Guide to the Human Genome
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Search of human proteins with 239757732

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239757732 PREDICTED: similar to KIAA1654 protein [Homo
sapiens]
         (110 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239757732 PREDICTED: similar to KIAA1654 protein [Homo sapiens]    219   5e-58
gi|219521907 carboxylesterase 7 isoform 1 [Homo sapiens]               33   0.049
gi|21450749 carboxylesterase 7 isoform 2 [Homo sapiens]                33   0.049
gi|4504211 guanylate cyclase 1, soluble, alpha 2 [Homo sapiens]        29   0.71 
gi|19923122 cholinergic receptor, nicotinic, alpha 3 [Homo sapiens]    29   0.93 
gi|231571356 nitric oxide synthase 3 isoform 4 [Homo sapiens]          28   1.2  
gi|231571329 nitric oxide synthase 3 isoform 3 [Homo sapiens]          28   1.2  
gi|231571314 nitric oxide synthase 3 isoform 2 [Homo sapiens]          28   1.2  
gi|40254422 nitric oxide synthase 3 isoform 1 [Homo sapiens]           28   1.2  
gi|169215908 PREDICTED: family with sequence similarity 108, mem...    28   1.2  
gi|169215726 PREDICTED: family with sequence similarity 108, mem...    28   1.2  
gi|239746656 PREDICTED: hypothetical protein LOC729495 [Homo sap...    28   1.2  
gi|66346723 mitochondrial phosphoenolpyruvate carboxykinase 2 is...    28   1.2  
gi|190194360 protocadherin 20 [Homo sapiens]                           28   1.2  
gi|239754641 PREDICTED: hypothetical protein [Homo sapiens]            28   1.6  
gi|239749183 PREDICTED: hypothetical protein XP_002346949 [Homo ...    28   1.6  
gi|239743263 PREDICTED: hypothetical protein XP_002342813 [Homo ...    28   1.6  
gi|239508944 PREDICTED: hypothetical protein [Homo sapiens]            28   1.6  
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         28   1.6  
gi|118402590 myosin XV [Homo sapiens]                                  27   2.7  
gi|169167066 PREDICTED: hypothetical protein [Homo sapiens]            27   2.7  
gi|113416187 PREDICTED: hypothetical protein [Homo sapiens]            27   2.7  
gi|113415691 PREDICTED: hypothetical protein [Homo sapiens]            27   2.7  
gi|239740773 PREDICTED: similar to diffuse panbronchiolitis crit...    27   2.7  
gi|157909822 pragmin [Homo sapiens]                                    27   2.7  
gi|31542509 ADP-dependent glucokinase [Homo sapiens]                   27   2.7  
gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]         27   2.7  
gi|239756961 PREDICTED: hypothetical protein [Homo sapiens]            27   3.5  
gi|133892686 hypothetical protein LOC727830 [Homo sapiens]             27   4.6  
gi|12669911 E2F transcription factor 1 [Homo sapiens]                  26   6.0  

>gi|239757732 PREDICTED: similar to KIAA1654 protein [Homo sapiens]
          Length = 110

 Score =  219 bits (557), Expect = 5e-58
 Identities = 110/110 (100%), Positives = 110/110 (100%)

Query: 1   MTMTVARKSNGLVQSPALAAGLKAQICMGKVWSQGAEGGEPAQEGPCSSDLLLWSLLATP 60
           MTMTVARKSNGLVQSPALAAGLKAQICMGKVWSQGAEGGEPAQEGPCSSDLLLWSLLATP
Sbjct: 1   MTMTVARKSNGLVQSPALAAGLKAQICMGKVWSQGAEGGEPAQEGPCSSDLLLWSLLATP 60

Query: 61  PAQGRPSPVSSYLAPALNALLVSSLQWSSLQPNLKVAASTLTLSLLCSAP 110
           PAQGRPSPVSSYLAPALNALLVSSLQWSSLQPNLKVAASTLTLSLLCSAP
Sbjct: 61  PAQGRPSPVSSYLAPALNALLVSSLQWSSLQPNLKVAASTLTLSLLCSAP 110


>gi|219521907 carboxylesterase 7 isoform 1 [Homo sapiens]
          Length = 575

 Score = 33.1 bits (74), Expect = 0.049
 Identities = 27/86 (31%), Positives = 38/86 (44%), Gaps = 5/86 (5%)

Query: 25  QICMGKVWSQGAEGGEPAQEGPCSSDLLLWSLLATPPAQGRPSPVSSYL-----APALNA 79
           QI +  +W   A    P+ EGP  +  L W         G P PV+ +L     AP L +
Sbjct: 10  QILIWAIWVLAAPTKGPSAEGPQRNTRLGWIQGKQVTVLGSPVPVNVFLGVPFAAPPLGS 69

Query: 80  LLVSSLQWSSLQPNLKVAASTLTLSL 105
           L  ++ Q +S   NL+ A S   L L
Sbjct: 70  LRFTNPQPASPWDNLREATSYPNLCL 95


>gi|21450749 carboxylesterase 7 isoform 2 [Homo sapiens]
          Length = 525

 Score = 33.1 bits (74), Expect = 0.049
 Identities = 27/86 (31%), Positives = 38/86 (44%), Gaps = 5/86 (5%)

Query: 25  QICMGKVWSQGAEGGEPAQEGPCSSDLLLWSLLATPPAQGRPSPVSSYL-----APALNA 79
           QI +  +W   A    P+ EGP  +  L W         G P PV+ +L     AP L +
Sbjct: 10  QILIWAIWVLAAPTKGPSAEGPQRNTRLGWIQGKQVTVLGSPVPVNVFLGVPFAAPPLGS 69

Query: 80  LLVSSLQWSSLQPNLKVAASTLTLSL 105
           L  ++ Q +S   NL+ A S   L L
Sbjct: 70  LRFTNPQPASPWDNLREATSYPNLCL 95


>gi|4504211 guanylate cyclase 1, soluble, alpha 2 [Homo sapiens]
          Length = 732

 Score = 29.3 bits (64), Expect = 0.71
 Identities = 13/36 (36%), Positives = 18/36 (50%)

Query: 41 PAQEGPCSSDLLLWSLLATPPAQGRPSPVSSYLAPA 76
          P +EG C    L W+   +PP    PSP ++  A A
Sbjct: 23 PEEEGECPLSRLCWNGSRSPPGPLEPSPAAAAAAAA 58


>gi|19923122 cholinergic receptor, nicotinic, alpha 3 [Homo sapiens]
          Length = 505

 Score = 28.9 bits (63), Expect = 0.93
 Identities = 14/47 (29%), Positives = 20/47 (42%)

Query: 1   MTMTVARKSNGLVQSPALAAGLKAQICMGKVWSQGAEGGEPAQEGPC 47
           MT   + + N     P   A L    C  +  S+G + G P Q+G C
Sbjct: 356 MTRPTSNEGNAQKPRPLYGAELSNLNCFSRAESKGCKEGYPCQDGMC 402


>gi|231571356 nitric oxide synthase 3 isoform 4 [Homo sapiens]
          Length = 629

 Score = 28.5 bits (62), Expect = 1.2
 Identities = 13/26 (50%), Positives = 16/26 (61%)

Query: 43  QEGPCSSDLLLWSLLATPPAQGRPSP 68
           Q+GPC+    L SL+     QGRPSP
Sbjct: 90  QDGPCTPRRCLGSLVFPRKLQGRPSP 115


>gi|231571329 nitric oxide synthase 3 isoform 3 [Homo sapiens]
          Length = 614

 Score = 28.5 bits (62), Expect = 1.2
 Identities = 13/26 (50%), Positives = 16/26 (61%)

Query: 43  QEGPCSSDLLLWSLLATPPAQGRPSP 68
           Q+GPC+    L SL+     QGRPSP
Sbjct: 90  QDGPCTPRRCLGSLVFPRKLQGRPSP 115


>gi|231571314 nitric oxide synthase 3 isoform 2 [Homo sapiens]
          Length = 596

 Score = 28.5 bits (62), Expect = 1.2
 Identities = 13/26 (50%), Positives = 16/26 (61%)

Query: 43  QEGPCSSDLLLWSLLATPPAQGRPSP 68
           Q+GPC+    L SL+     QGRPSP
Sbjct: 90  QDGPCTPRRCLGSLVFPRKLQGRPSP 115


>gi|40254422 nitric oxide synthase 3 isoform 1 [Homo sapiens]
          Length = 1203

 Score = 28.5 bits (62), Expect = 1.2
 Identities = 13/26 (50%), Positives = 16/26 (61%)

Query: 43  QEGPCSSDLLLWSLLATPPAQGRPSP 68
           Q+GPC+    L SL+     QGRPSP
Sbjct: 90  QDGPCTPRRCLGSLVFPRKLQGRPSP 115


>gi|169215908 PREDICTED: family with sequence similarity 108, member
           A5 [Homo sapiens]
          Length = 403

 Score = 28.5 bits (62), Expect = 1.2
 Identities = 18/51 (35%), Positives = 23/51 (45%), Gaps = 3/51 (5%)

Query: 35  GAEGGEPAQEGPCSSDLL---LWSLLATPPAQGRPSPVSSYLAPALNALLV 82
           G  GG PA+E P  + L    L  L   PP  GR +   ++L P     LV
Sbjct: 83  GGPGGGPAREAPAMNGLSLSELCCLFCYPPCPGRIAAKLAFLPPEATYSLV 133


>gi|169215726 PREDICTED: family with sequence similarity 108, member
           A5 [Homo sapiens]
          Length = 403

 Score = 28.5 bits (62), Expect = 1.2
 Identities = 18/51 (35%), Positives = 23/51 (45%), Gaps = 3/51 (5%)

Query: 35  GAEGGEPAQEGPCSSDLL---LWSLLATPPAQGRPSPVSSYLAPALNALLV 82
           G  GG PA+E P  + L    L  L   PP  GR +   ++L P     LV
Sbjct: 83  GGPGGGPAREAPAMNGLSLSELCCLFCYPPCPGRIAAKLAFLPPEATYSLV 133


>gi|239746656 PREDICTED: hypothetical protein LOC729495 [Homo
           sapiens]
          Length = 403

 Score = 28.5 bits (62), Expect = 1.2
 Identities = 18/51 (35%), Positives = 23/51 (45%), Gaps = 3/51 (5%)

Query: 35  GAEGGEPAQEGPCSSDLL---LWSLLATPPAQGRPSPVSSYLAPALNALLV 82
           G  GG PA+E P  + L    L  L   PP  GR +   ++L P     LV
Sbjct: 83  GGPGGGPAREAPAMNGLSLSELCCLFCYPPCPGRIAAKLAFLPPEATYSLV 133


>gi|66346723 mitochondrial phosphoenolpyruvate carboxykinase 2
           isoform 2 precursor [Homo sapiens]
          Length = 441

 Score = 28.5 bits (62), Expect = 1.2
 Identities = 15/44 (34%), Positives = 20/44 (45%)

Query: 18  LAAGLKAQICMGKVWSQGAEGGEPAQEGPCSSDLLLWSLLATPP 61
           L  G+     +GK W  G  GGE   + P  S L++  L   PP
Sbjct: 395 LPPGVTVTSWLGKPWKPGMCGGEGVAQPPGLSTLMVEKLSPQPP 438


>gi|190194360 protocadherin 20 [Homo sapiens]
          Length = 951

 Score = 28.5 bits (62), Expect = 1.2
 Identities = 14/43 (32%), Positives = 19/43 (44%)

Query: 31  VWSQGAEGGEPAQEGPCSSDLLLWSLLATPPAQGRPSPVSSYL 73
           +W +  +GGEPA        +LL  +   PP    P    SYL
Sbjct: 710 LWVEAVDGGEPALSSTAKITILLLDINDNPPLVLFPQSNMSYL 752


>gi|239754641 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 229

 Score = 28.1 bits (61), Expect = 1.6
 Identities = 13/41 (31%), Positives = 20/41 (48%), Gaps = 1/41 (2%)

Query: 27  CMGKVWSQGAEGGEPAQEGPCSSDLLLWSLLATPPAQGRPS 67
           C+   W+ G     PA+  P  ++   W  +A PP  GRP+
Sbjct: 110 CIRCRWASGPAAWWPARAAPAGAETREWRTVARPP-PGRPA 149


>gi|239749183 PREDICTED: hypothetical protein XP_002346949 [Homo
           sapiens]
          Length = 229

 Score = 28.1 bits (61), Expect = 1.6
 Identities = 13/41 (31%), Positives = 20/41 (48%), Gaps = 1/41 (2%)

Query: 27  CMGKVWSQGAEGGEPAQEGPCSSDLLLWSLLATPPAQGRPS 67
           C+   W+ G     PA+  P  ++   W  +A PP  GRP+
Sbjct: 110 CIRCRWASGPAAWWPARAAPAGAETREWRTVARPP-PGRPA 149


>gi|239743263 PREDICTED: hypothetical protein XP_002342813 [Homo
           sapiens]
          Length = 229

 Score = 28.1 bits (61), Expect = 1.6
 Identities = 13/41 (31%), Positives = 20/41 (48%), Gaps = 1/41 (2%)

Query: 27  CMGKVWSQGAEGGEPAQEGPCSSDLLLWSLLATPPAQGRPS 67
           C+   W+ G     PA+  P  ++   W  +A PP  GRP+
Sbjct: 110 CIRCRWASGPAAWWPARAAPAGAETREWRTVARPP-PGRPA 149


>gi|239508944 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 229

 Score = 28.1 bits (61), Expect = 1.6
 Identities = 13/41 (31%), Positives = 20/41 (48%), Gaps = 1/41 (2%)

Query: 27  CMGKVWSQGAEGGEPAQEGPCSSDLLLWSLLATPPAQGRPS 67
           C+   W+ G     PA+  P  ++   W  +A PP  GRP+
Sbjct: 110 CIRCRWASGPAAWWPARAAPAGAETREWRTVARPP-PGRPA 149


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 28.1 bits (61), Expect = 1.6
 Identities = 19/65 (29%), Positives = 27/65 (41%), Gaps = 7/65 (10%)

Query: 41   PAQEGPCSSDLLLWSLLATPPAQGRPSPVSSYLAPALNALLVSSLQWSSLQPNLKVAAST 100
            P+Q  PCSS         TPP    P P  + L    + LL+         P++ ++AS 
Sbjct: 2488 PSQIPPCSSPACTPPPACTPPPAHTPPPAQTCLVTPSSPLLLG-------PPSVPISASV 2540

Query: 101  LTLSL 105
              L L
Sbjct: 2541 TNLPL 2545


>gi|118402590 myosin XV [Homo sapiens]
          Length = 3530

 Score = 27.3 bits (59), Expect = 2.7
 Identities = 18/55 (32%), Positives = 25/55 (45%), Gaps = 4/55 (7%)

Query: 41  PAQEGPCSSDLLLWSLLATPPAQGRP----SPVSSYLAPALNALLVSSLQWSSLQ 91
           P    P    L  WS L +PP   RP     P +  L+PAL+ L   +  + SL+
Sbjct: 644 PPAPQPAPRTLSHWSALLSPPVPPRPPSSGPPPAPPLSPALSGLPRPASPYGSLR 698



 Score = 26.2 bits (56), Expect = 6.0
 Identities = 20/59 (33%), Positives = 25/59 (42%), Gaps = 1/59 (1%)

Query: 34  QGAEGGEPAQEGPCSSDLLLWSLLATPPAQGRPSPVSSYLAPALNALLVSSLQWSSLQP 92
           +GA  G P    P +S    WS LA+P    R SP   Y +P        SL+    QP
Sbjct: 751 RGAAFGFPGAS-PRASRRRAWSPLASPQPSLRSSPGLGYCSPLAPPSPQLSLRTGPFQP 808


>gi|169167066 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 262

 Score = 27.3 bits (59), Expect = 2.7
 Identities = 14/42 (33%), Positives = 21/42 (50%), Gaps = 1/42 (2%)

Query: 28 MGKVWSQGAEGGEP-AQEGPCSSDLLLWSLLATPPAQGRPSP 68
          MGK   +G E G P + + P S+D +  +    PP    P+P
Sbjct: 1  MGKAGGEGGEAGPPMSAQPPSSADTVPGTTYPPPPPPPPPTP 42


>gi|113416187 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 262

 Score = 27.3 bits (59), Expect = 2.7
 Identities = 14/42 (33%), Positives = 21/42 (50%), Gaps = 1/42 (2%)

Query: 28 MGKVWSQGAEGGEP-AQEGPCSSDLLLWSLLATPPAQGRPSP 68
          MGK   +G E G P + + P S+D +  +    PP    P+P
Sbjct: 1  MGKAGGEGGEAGPPMSAQPPSSADTVPGTTYPPPPPPPPPTP 42


>gi|113415691 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 262

 Score = 27.3 bits (59), Expect = 2.7
 Identities = 14/42 (33%), Positives = 21/42 (50%), Gaps = 1/42 (2%)

Query: 28 MGKVWSQGAEGGEP-AQEGPCSSDLLLWSLLATPPAQGRPSP 68
          MGK   +G E G P + + P S+D +  +    PP    P+P
Sbjct: 1  MGKAGGEGGEAGPPMSAQPPSSADTVPGTTYPPPPPPPPPTP 42


>gi|239740773 PREDICTED: similar to diffuse panbronchiolitis critical
            region 1 [Homo sapiens]
          Length = 1400

 Score = 27.3 bits (59), Expect = 2.7
 Identities = 22/107 (20%), Positives = 44/107 (41%)

Query: 4    TVARKSNGLVQSPALAAGLKAQICMGKVWSQGAEGGEPAQEGPCSSDLLLWSLLATPPAQ 63
            T +  S G   + A  +  +    M    + G+E    + + P ++    +S     PA+
Sbjct: 1259 TASESSTGSETTRASTSATEVTTAMTTAMTTGSETAVVSTKAPVTTTQSGFSTATVMPAK 1318

Query: 64   GRPSPVSSYLAPALNALLVSSLQWSSLQPNLKVAASTLTLSLLCSAP 110
               + VS+  +  L    + S+  S    +  +A+ + TLS + S P
Sbjct: 1319 TTTASVSTTASTTLYQNTIDSVAKSVPTMDSTIASKSTTLSKIVSVP 1365


>gi|157909822 pragmin [Homo sapiens]
          Length = 1402

 Score = 27.3 bits (59), Expect = 2.7
 Identities = 13/35 (37%), Positives = 18/35 (51%), Gaps = 1/35 (2%)

Query: 5   VARKSNGLVQSPALAAGLKAQICMGKVWSQGAEGG 39
           V  KS   ++  A A G + Q+C G  W+Q A  G
Sbjct: 423 VPSKSQAKIEHAAAAQG-QGQVCTGNAWAQKAASG 456


>gi|31542509 ADP-dependent glucokinase [Homo sapiens]
          Length = 496

 Score = 27.3 bits (59), Expect = 2.7
 Identities = 19/41 (46%), Positives = 22/41 (53%), Gaps = 2/41 (4%)

Query: 44 EGPCSSDLLLWSLLATPPAQGRPSPVS--SYLAPALNALLV 82
          E P S+   LWS L   PA   P PVS    LA A +AL+V
Sbjct: 26 ELPGSALRSLWSSLCLGPAPAPPGPVSPEGRLAAAWDALIV 66


>gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]
          Length = 1003

 Score = 27.3 bits (59), Expect = 2.7
 Identities = 29/86 (33%), Positives = 38/86 (44%), Gaps = 13/86 (15%)

Query: 14  QSPALAAGLKAQICMGKVWSQGAEGGEPAQEGPCSSDLLLWSLL-ATPPAQGRPSPVSSY 72
           Q P  +A +   + +G +      GG P  EGP +   L  SLL A   AQ  P P  S 
Sbjct: 287 QPPVSSATMHLPLVLGPL------GGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPST 340

Query: 73  L------APALNALLVSSLQWSSLQP 92
           L      A A +A   SSL+ S  +P
Sbjct: 341 LQGRRPRAQAPSASHSSSLRPSQRRP 366


>gi|239756961 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 105

 Score = 26.9 bits (58), Expect = 3.5
 Identities = 22/65 (33%), Positives = 30/65 (46%), Gaps = 14/65 (21%)

Query: 12  LVQSPALAAGLKAQICMGKVWSQGAEGGEPAQEGPCSSDLLL------WS--LLATP-PA 62
           L+ S     G + ++C G      A+G  PA  G CS  LLL      W+  +L +P P 
Sbjct: 45  LICSGGFIPGTRPRLCSGH-----ADGNIPAGPGLCSPQLLLPGGQLFWAPEVLRSPFPG 99

Query: 63  QGRPS 67
            G PS
Sbjct: 100 PGTPS 104


>gi|133892686 hypothetical protein LOC727830 [Homo sapiens]
          Length = 1347

 Score = 26.6 bits (57), Expect = 4.6
 Identities = 20/65 (30%), Positives = 31/65 (47%), Gaps = 3/65 (4%)

Query: 29  GKVWSQGAEGGEPAQEGPCSSDLLLWSLLATPPAQGR-PSPVSSYLAPALNALLVSSLQW 87
           G+V  +  +G   +   P      + SLLA+P  Q + P  ++S  +P      VSSL  
Sbjct: 124 GEVGERAPDGASQSSHEPMEDAAPILSLLASPDPQAKHPQDLASTPSPGPMTTSVSSL-- 181

Query: 88  SSLQP 92
           S+ QP
Sbjct: 182 SASQP 186


>gi|12669911 E2F transcription factor 1 [Homo sapiens]
          Length = 437

 Score = 26.2 bits (56), Expect = 6.0
 Identities = 17/33 (51%), Positives = 18/33 (54%), Gaps = 6/33 (18%)

Query: 45 GPCSSDLLLWSLLATPPAQGRPSPVSSYLAPAL 77
          GPC  DLLL+   ATP A   P P  S   PAL
Sbjct: 57 GPCDPDLLLF---ATPQA---PRPTPSAPRPAL 83


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.125    0.373 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,785,442
Number of Sequences: 37866
Number of extensions: 234188
Number of successful extensions: 681
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 24
Number of HSP's that attempted gapping in prelim test: 656
Number of HSP's gapped (non-prelim): 49
length of query: 110
length of database: 18,247,518
effective HSP length: 80
effective length of query: 30
effective length of database: 15,218,238
effective search space: 456547140
effective search space used: 456547140
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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