Guide to the Human Genome
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Name: CHRNA3 Sequence: fasta or formatted (505aa) NCBI GI: 19923122
Description:

cholinergic receptor, nicotinic, alpha 3

Referenced in:

Acetylcholine

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.3         27           1
 C cysteine            2.6         13           2
 D aspartate           4.6         23           2
 E glutamate           5.5         28           2
 F phenylalanine       4.6         23           1
 G glycine             4.0         20           2
 H histidine           1.4          7           2
 I isoleucine          7.9         40           2
 K lysine              5.7         29           1
 L leucine            12.3         62           7
 M methionine          2.8         14           1
 N asparagine          4.4         22           2
 P proline             5.7         29           2
 Q glutamine           2.4         12           1
 R arginine            3.6         18           2
 S serine              7.9         40           4
 T threonine           5.3         27           2
 V valine              7.3         37           1
 W tryptophan          2.2         11           1
 Y tyrosine            4.6         23           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   cholinergic receptor, nicotinic, alpha 3 
CHRNA6                0.635   cholinergic receptor, nicotinic, alpha 6 
CHRNA2                0.524   cholinergic receptor, nicotinic, alpha polypeptide ...
CHRNA4                0.463   cholinergic receptor, nicotinic, alpha 4 subunit prec...
CHRNB4                0.422   cholinergic receptor, nicotinic, beta 4 
CHRNA1                0.421   nicotinic cholinergic receptor alpha 1 isoform b prec...
CHRNB2                0.419   neuronal nicotinic acetylcholine receptor beta 2 prec...
CHRNA1                0.407   nicotinic cholinergic receptor alpha 1 isoform a pre...
CHRNB3                0.391   cholinergic receptor, nicotinic, beta polypeptide 3 [...
CHRNA5                0.368   cholinergic receptor, nicotinic, alpha 5 
CHRNA7                0.333   cholinergic receptor, nicotinic, alpha 7 precursor [H...
CHRNB1                0.318   nicotinic acetylcholine receptor beta 1 subunit prec...
CHRND                 0.314   nicotinic acetylcholine receptor delta polypeptide pr...
CHRNA9                0.291   cholinergic receptor, nicotinic, alpha 9 precursor [...
CHRNA10               0.280   cholinergic receptor, nicotinic, alpha 10 
CHRNE                 0.276   nicotinic acetylcholine receptor epsilon polypeptide ...
CHRNG                 0.253   cholinergic receptor, nicotinic, gamma polypeptide p...
CHRFAM7A              0.224   CHRNA7-FAM7A fusion isoform 1 
HTR3A                 0.177   5-hydroxytryptamine (serotonin) receptor 3A isoform...
HTR3A                 0.173   5-hydroxytryptamine (serotonin) receptor 3A isoform...
CHRFAM7A              0.166   CHRNA7-FAM7A fusion isoform 2 
HTR3A                 0.161   5-hydroxytryptamine (serotonin) receptor 3A isoform...
HTR3E                 0.134   5-hydroxytryptamine receptor 3 subunit E 
HTR3C                 0.129   5-hydroxytryptamine receptor 3 subunit C 
HTR3B                 0.122   5-hydroxytryptamine (serotonin) receptor 3B precursor...
GLRB                  0.064   glycine receptor, beta 
GABRG2                0.058   gamma-aminobutyric acid A receptor, gamma 2 isoform ...
GABRG2                0.058   gamma-aminobutyric acid A receptor, gamma 2 isoform ...
GABRB1                0.055   gamma-aminobutyric acid (GABA) A receptor, beta 1 p...
GABRG3                0.054   gamma-aminobutyric acid (GABA) A receptor, gamma 3 ...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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