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Search of human proteins with 239757286
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239757286 PREDICTED: similar to Fc fragment of IgG binding
protein [Homo sapiens]
(1472 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239757286 PREDICTED: similar to Fc fragment of IgG binding pr... 3055 0.0
gi|239751787 PREDICTED: hypothetical protein XP_002348012 [Homo ... 2726 0.0
gi|154146262 Fc fragment of IgG binding protein [Homo sapiens] 2726 0.0
gi|239757282 PREDICTED: similar to Fc fragment of IgG binding pr... 753 0.0
gi|134268640 tectorin alpha precursor [Homo sapiens] 560 e-159
gi|16554449 zonadhesin isoform 3 [Homo sapiens] 555 e-157
gi|27881494 zonadhesin isoform 6 [Homo sapiens] 555 e-157
gi|239757284 PREDICTED: similar to Fc fragment of IgG binding pr... 331 4e-90
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens] 318 3e-86
gi|169202626 PREDICTED: similar to mucin 5, partial [Homo sapiens] 316 9e-86
gi|89191868 von Willebrand factor preproprotein [Homo sapiens] 314 3e-85
gi|161019170 mucin 5AC [Homo sapiens] 308 2e-83
gi|134031945 SCO-spondin [Homo sapiens] 300 9e-81
gi|239755545 PREDICTED: otogelin isoform 1 [Homo sapiens] 280 7e-75
gi|239755543 PREDICTED: otogelin isoform 2 [Homo sapiens] 280 7e-75
gi|239749989 PREDICTED: otogelin isoform 2 [Homo sapiens] 280 7e-75
gi|239749987 PREDICTED: otogelin isoform 1 [Homo sapiens] 280 7e-75
gi|239744300 PREDICTED: otogelin isoform 2 [Homo sapiens] 280 7e-75
gi|239744298 PREDICTED: otogelin isoform 1 [Homo sapiens] 280 7e-75
gi|239755901 PREDICTED: chromosome 12 open reading frame 64 [Hom... 268 4e-71
gi|239750386 PREDICTED: chromosome 12 open reading frame 64 [Hom... 268 4e-71
gi|239744688 PREDICTED: hypothetical protein LOC283310 [Homo sap... 268 4e-71
gi|151301154 mucin 6, gastric [Homo sapiens] 250 6e-66
gi|116284392 mucin 2 precursor [Homo sapiens] 246 2e-64
gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo ... 221 4e-57
gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo ... 221 4e-57
gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens] 199 1e-50
gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens] 180 1e-44
gi|37693519 BMP-binding endothelial regulator precursor protein ... 172 2e-42
gi|239755776 PREDICTED: similar to Mucin-19 [Homo sapiens] 130 9e-30
>gi|239757286 PREDICTED: similar to Fc fragment of IgG binding protein
[Homo sapiens]
Length = 1472
Score = 3055 bits (7921), Expect = 0.0
Identities = 1472/1472 (100%), Positives = 1472/1472 (100%)
Query: 1 MRMAASSRKLASSAWHVAQGVAQKLHYIALPQGWPCSSRDLQPWVPYGAGGYSGLEQPSC 60
MRMAASSRKLASSAWHVAQGVAQKLHYIALPQGWPCSSRDLQPWVPYGAGGYSGLEQPSC
Sbjct: 1 MRMAASSRKLASSAWHVAQGVAQKLHYIALPQGWPCSSRDLQPWVPYGAGGYSGLEQPSC 60
Query: 61 GSKSGEDWISGPTTVFSQPGLTQEASVDLKNTGREEFLTAFLQNYQLAYSKAYPRLLISS 120
GSKSGEDWISGPTTVFSQPGLTQEASVDLKNTGREEFLTAFLQNYQLAYSKAYPRLLISS
Sbjct: 61 GSKSGEDWISGPTTVFSQPGLTQEASVDLKNTGREEFLTAFLQNYQLAYSKAYPRLLISS 120
Query: 121 LSESPASVSILSQADNTSKKVTVRPGESVMVNISAKAEMIGSKIFQHAVVIHSDYAISVQ 180
LSESPASVSILSQADNTSKKVTVRPGESVMVNISAKAEMIGSKIFQHAVVIHSDYAISVQ
Sbjct: 121 LSESPASVSILSQADNTSKKVTVRPGESVMVNISAKAEMIGSKIFQHAVVIHSDYAISVQ 180
Query: 181 ALNAKPDTAELTLLRPIQALGTEYFVLTPPGTSARNVKEFAVVAGAAGASVSVTLKGSVT 240
ALNAKPDTAELTLLRPIQALGTEYFVLTPPGTSARNVKEFAVVAGAAGASVSVTLKGSVT
Sbjct: 181 ALNAKPDTAELTLLRPIQALGTEYFVLTPPGTSARNVKEFAVVAGAAGASVSVTLKGSVT 240
Query: 241 FNGKFYPAGDVLRVTLQPYNVAQLQSSVDLSGSKVTASSPVAVLSGHSCAQKHTTCNHVV 300
FNGKFYPAGDVLRVTLQPYNVAQLQSSVDLSGSKVTASSPVAVLSGHSCAQKHTTCNHVV
Sbjct: 241 FNGKFYPAGDVLRVTLQPYNVAQLQSSVDLSGSKVTASSPVAVLSGHSCAQKHTTCNHVV 300
Query: 301 EQLLPTSAWGTHYVVPTLASQSRYDLAFVVASQATKLTYNHGGITGSRGLQAGDVVEFEV 360
EQLLPTSAWGTHYVVPTLASQSRYDLAFVVASQATKLTYNHGGITGSRGLQAGDVVEFEV
Sbjct: 301 EQLLPTSAWGTHYVVPTLASQSRYDLAFVVASQATKLTYNHGGITGSRGLQAGDVVEFEV 360
Query: 361 RPSWPLYLSANVGIQVLLFGTGAIRNEVTYDPYLVLIPDVAAYCPAYVVKSVPGCEGVAL 420
RPSWPLYLSANVGIQVLLFGTGAIRNEVTYDPYLVLIPDVAAYCPAYVVKSVPGCEGVAL
Sbjct: 361 RPSWPLYLSANVGIQVLLFGTGAIRNEVTYDPYLVLIPDVAAYCPAYVVKSVPGCEGVAL 420
Query: 421 VVAQTKAISGLTIDGHAVGAKLTWEAVPGSEFSYAEVELGTADMIHTAEATTNLGLLTFG 480
VVAQTKAISGLTIDGHAVGAKLTWEAVPGSEFSYAEVELGTADMIHTAEATTNLGLLTFG
Sbjct: 421 VVAQTKAISGLTIDGHAVGAKLTWEAVPGSEFSYAEVELGTADMIHTAEATTNLGLLTFG 480
Query: 481 LAKAIGYATAADCGRTVLSPVEPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPH 540
LAKAIGYATAADCGRTVLSPVEPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPH
Sbjct: 481 LAKAIGYATAADCGRTVLSPVEPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPH 540
Query: 541 YTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHS 600
YTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHS
Sbjct: 541 YTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHS 600
Query: 601 VSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSL 660
VSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSL
Sbjct: 601 VSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSL 660
Query: 661 PARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPA 720
PARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPA
Sbjct: 661 PARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPA 720
Query: 721 CTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLS 780
CTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLS
Sbjct: 721 CTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLS 780
Query: 781 AYAQACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEG 840
AYAQACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEG
Sbjct: 781 AYAQACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEG 840
Query: 841 CVCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQ 900
CVCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQ
Sbjct: 841 CVCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQ 900
Query: 901 SCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAA 960
SCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAA
Sbjct: 901 SCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAA 960
Query: 961 LPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQ 1020
LPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQ
Sbjct: 961 LPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQ 1020
Query: 1021 VQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGG 1080
VQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGG
Sbjct: 1021 VQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGG 1080
Query: 1081 GQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECH 1140
GQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECH
Sbjct: 1081 GQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECH 1140
Query: 1141 SKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPH 1200
SKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPH
Sbjct: 1141 SKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPH 1200
Query: 1201 SHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHP 1260
SHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHP
Sbjct: 1201 SHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHP 1260
Query: 1261 PGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPH 1320
PGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPH
Sbjct: 1261 PGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPH 1320
Query: 1321 YTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFT 1380
YTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFT
Sbjct: 1321 YTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFT 1380
Query: 1381 LRLEQRQWKVTVRADGEQGARGLWVGGTQAALSPGVGGTEMRVHVRGLGSLRTEDASQNP 1440
LRLEQRQWKVTVRADGEQGARGLWVGGTQAALSPGVGGTEMRVHVRGLGSLRTEDASQNP
Sbjct: 1381 LRLEQRQWKVTVRADGEQGARGLWVGGTQAALSPGVGGTEMRVHVRGLGSLRTEDASQNP 1440
Query: 1441 EWEANEGGVIRDLGAAPPSLSLSLHPLFTSMH 1472
EWEANEGGVIRDLGAAPPSLSLSLHPLFTSMH
Sbjct: 1441 EWEANEGGVIRDLGAAPPSLSLSLHPLFTSMH 1472
>gi|239751787 PREDICTED: hypothetical protein XP_002348012 [Homo
sapiens]
Length = 3003
Score = 2726 bits (7067), Expect = 0.0
Identities = 1313/1313 (100%), Positives = 1313/1313 (100%)
Query: 80 GLTQEASVDLKNTGREEFLTAFLQNYQLAYSKAYPRLLISSLSESPASVSILSQADNTSK 139
GLTQEASVDLKNTGREEFLTAFLQNYQLAYSKAYPRLLISSLSESPASVSILSQADNTSK
Sbjct: 19 GLTQEASVDLKNTGREEFLTAFLQNYQLAYSKAYPRLLISSLSESPASVSILSQADNTSK 78
Query: 140 KVTVRPGESVMVNISAKAEMIGSKIFQHAVVIHSDYAISVQALNAKPDTAELTLLRPIQA 199
KVTVRPGESVMVNISAKAEMIGSKIFQHAVVIHSDYAISVQALNAKPDTAELTLLRPIQA
Sbjct: 79 KVTVRPGESVMVNISAKAEMIGSKIFQHAVVIHSDYAISVQALNAKPDTAELTLLRPIQA 138
Query: 200 LGTEYFVLTPPGTSARNVKEFAVVAGAAGASVSVTLKGSVTFNGKFYPAGDVLRVTLQPY 259
LGTEYFVLTPPGTSARNVKEFAVVAGAAGASVSVTLKGSVTFNGKFYPAGDVLRVTLQPY
Sbjct: 139 LGTEYFVLTPPGTSARNVKEFAVVAGAAGASVSVTLKGSVTFNGKFYPAGDVLRVTLQPY 198
Query: 260 NVAQLQSSVDLSGSKVTASSPVAVLSGHSCAQKHTTCNHVVEQLLPTSAWGTHYVVPTLA 319
NVAQLQSSVDLSGSKVTASSPVAVLSGHSCAQKHTTCNHVVEQLLPTSAWGTHYVVPTLA
Sbjct: 199 NVAQLQSSVDLSGSKVTASSPVAVLSGHSCAQKHTTCNHVVEQLLPTSAWGTHYVVPTLA 258
Query: 320 SQSRYDLAFVVASQATKLTYNHGGITGSRGLQAGDVVEFEVRPSWPLYLSANVGIQVLLF 379
SQSRYDLAFVVASQATKLTYNHGGITGSRGLQAGDVVEFEVRPSWPLYLSANVGIQVLLF
Sbjct: 259 SQSRYDLAFVVASQATKLTYNHGGITGSRGLQAGDVVEFEVRPSWPLYLSANVGIQVLLF 318
Query: 380 GTGAIRNEVTYDPYLVLIPDVAAYCPAYVVKSVPGCEGVALVVAQTKAISGLTIDGHAVG 439
GTGAIRNEVTYDPYLVLIPDVAAYCPAYVVKSVPGCEGVALVVAQTKAISGLTIDGHAVG
Sbjct: 319 GTGAIRNEVTYDPYLVLIPDVAAYCPAYVVKSVPGCEGVALVVAQTKAISGLTIDGHAVG 378
Query: 440 AKLTWEAVPGSEFSYAEVELGTADMIHTAEATTNLGLLTFGLAKAIGYATAADCGRTVLS 499
AKLTWEAVPGSEFSYAEVELGTADMIHTAEATTNLGLLTFGLAKAIGYATAADCGRTVLS
Sbjct: 379 AKLTWEAVPGSEFSYAEVELGTADMIHTAEATTNLGLLTFGLAKAIGYATAADCGRTVLS 438
Query: 500 PVEPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTM 559
PVEPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTM
Sbjct: 439 PVEPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTM 498
Query: 560 VELCSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSR 619
VELCSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSR
Sbjct: 499 VELCSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSR 558
Query: 620 LPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDP 679
LPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDP
Sbjct: 559 LPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDP 618
Query: 680 ADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLT 739
ADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLT
Sbjct: 619 ADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLT 678
Query: 740 KLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSP 799
KLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSP
Sbjct: 679 KLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSP 738
Query: 800 ANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASS 859
ANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASS
Sbjct: 739 ANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASS 798
Query: 860 CGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYP 919
CGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYP
Sbjct: 799 CGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYP 858
Query: 920 DRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVS 979
DRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVS
Sbjct: 859 DRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVS 918
Query: 980 YTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLT 1039
YTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLT
Sbjct: 919 YTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLT 978
Query: 1040 VTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRP 1099
VTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRP
Sbjct: 979 VTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRP 1038
Query: 1100 GCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLL 1159
GCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLL
Sbjct: 1039 GCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLL 1098
Query: 1160 PGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPV 1219
PGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPV
Sbjct: 1099 PGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPV 1158
Query: 1220 PGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQE 1279
PGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQE
Sbjct: 1159 PGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQE 1218
Query: 1280 GGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVL 1339
GGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVL
Sbjct: 1219 GGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVL 1278
Query: 1340 AQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTV 1392
AQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTV
Sbjct: 1279 AQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTV 1331
Score = 749 bits (1935), Expect = 0.0
Identities = 388/916 (42%), Positives = 516/916 (56%), Gaps = 33/916 (3%)
Query: 505 CEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVEL-C 563
C G+ C + C+ GG+ C+ A C GDPHY +FDGR++D GTC+Y + C
Sbjct: 1645 CHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGC 1704
Query: 564 SEDDT--LPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFV--LVDNQRSR 619
T L F+V KN++RG+ VSYV +VTV A ++S+ + E+G V V+ +
Sbjct: 1705 PGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGVLTA 1764
Query: 620 LPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDP 679
LPVS+++GR+ V Q +A++ FGL V+YDW+ ++ ++LP+ + VCGLCGN + +P
Sbjct: 1765 LPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNP 1824
Query: 680 ADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLT 739
+D + P+G LAP + SW+ D LC D C+ +CP C + + YEG CG L
Sbjct: 1825 NNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLA 1884
Query: 740 K-LDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRS 798
GPF CH + P F + CV D+C+ GG+R LC+ L++Y AC G+ + DWR+
Sbjct: 1885 SGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRA 1944
Query: 799 PANCPLSCPANSRYELCGPACPTSCNGAA---APSNCSGRPCVEGCVCLPGFVASGGACV 855
C ++CP NS YE+CGP CP SC A P+ C G PCVEGC C GFV S CV
Sbjct: 1945 QVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEG-PCVEGCQCDAGFVLSADRCV 2003
Query: 856 PASS-CGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSV-QNG 913
P ++ CGC G G E WAD C + C C + C SC GE C + +G
Sbjct: 2004 PLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPA-SCGLGEVCGLLPSG 2062
Query: 914 LLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSC-GQNAALPAFRVLVENEH 972
GC P CQ GDPHYV+ DG RFDF GTC YLL C G F V V NEH
Sbjct: 2063 QHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEH 2122
Query: 973 RGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVV 1032
RGSQ VSYTR+V ++ + + +P ++ VD V LPFQ D + G D VV
Sbjct: 2123 RGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQL-DSLLHAHLSGADVVV 2181
Query: 1033 RTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNS 1092
T GL++ +D ++ V +VP++YA +LCGLCGN+N DPADDL GG A
Sbjct: 2182 TTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAG-------- 2233
Query: 1093 WQEETRPGCGATEPGDCPKLDSLVAQQ-LQSKNECGILADPKGPFRECHSKLDPQGAVRD 1151
WQ GCG CP + Q+ + CG+++ GP CH + P +
Sbjct: 2234 WQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQG 2293
Query: 1152 CVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCP 1211
C+ D C + G G LC A+ATY AACQAAGA + WR + CPL CP HSHYE C CP
Sbjct: 2294 CLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCP 2353
Query: 1212 LSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGC 1271
+SC L P GC S C EGCVCD GF LSG++C+P+ CGC+H G Y+P G+ FYPGP C
Sbjct: 2354 VSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPEC 2413
Query: 1272 DSLCHCQEGGLVSC-ESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFD 1330
+ C C GG V+C E ++CGPHE C+ G C A G C A+G HY T DGR +D
Sbjct: 2414 ERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYD 2473
Query: 1331 FMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKV 1390
G+C YVLAQ C +PG F+++ E A G+ + + V VA + L Q Q +V
Sbjct: 2474 LHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGD-----LQRLLVTVAGQVVSLAQGQ-QV 2527
Query: 1391 TVRADGEQGARGLWVG 1406
TV DGE A + VG
Sbjct: 2528 TV--DGEAVALPVAVG 2541
Score = 749 bits (1933), Expect = 0.0
Identities = 394/957 (41%), Positives = 509/957 (53%), Gaps = 56/957 (5%)
Query: 504 SCEGMQ-CAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVEL 562
+C Q C AG+RC V G GC + C+ GDPHY +FDGRR+D MGTC+Y +V
Sbjct: 834 TCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGS 893
Query: 563 CSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPV 622
C ++ LPAF V +NEHRGS+ VSY V V A V++ R G VLVD+ LP
Sbjct: 894 CGQNAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPF 953
Query: 623 SLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADD 682
++G+++V++ G AVV FGL VTYDW+ ++ +P+ + + +CGLCGN+NGDPADD
Sbjct: 954 QAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADD 1013
Query: 683 FLTPDGALAPDAVEFASSWKLDDGDYLCEDGC----QNNCPACTPGQAQHYEGDRLCGML 738
G A +A+ F +SW+ + GC +CP AQ + CG+L
Sbjct: 1014 LALRGGGQAANALAFGNSWQEET-----RPGCGATEPGDCPKLDSLVAQQLQSKNECGIL 1068
Query: 739 TKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRS 798
GPF CH LDP+ + CVYD C++ G+ LC L+ YA AC G +V WRS
Sbjct: 1069 ADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRS 1128
Query: 799 PANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPAS 858
CPLSCP +S YE C CP SC P C G C EGCVC GF SG +C+P +
Sbjct: 1129 EELCPLSCPPHSHYEACSYGCPLSCGDLPVPGGC-GSECHEGCVCDEGFALSGESCLPLA 1187
Query: 859 SCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCY 918
SCGC QG PGQ + C C C V+C + SC E C G LGC
Sbjct: 1188 SCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGG-LVSC-ESSSCGPHEACQPSGGSLGCV 1245
Query: 919 PDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTV 978
TCQ SGDPHY +FDGRRFDFMGTC Y+L +CG L F VL EN G+ V
Sbjct: 1246 AVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRV 1305
Query: 979 SYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGL 1038
S TR + V+ + + + +V V+ V LP A+GQ++ + G D V+ TDFGL
Sbjct: 1306 SVTRVITVQVANFTLRLEQRQ-WKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGL 1364
Query: 1039 TVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETR 1098
V YD V VP +Y + +CGLCGN+NGDP DD G QA NA FGNSW EE
Sbjct: 1365 RVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSW-EEVV 1423
Query: 1099 PGCGATEPGDCP----------KLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGA 1148
P P CP K + ++ Q + CG+L+ P GP CH +DPQG
Sbjct: 1424 PDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGP 1483
Query: 1149 VRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSY 1208
++DC++D CL G LC + Y +ACQAAG V PWR+E CP+ CPP+SHYE C+
Sbjct: 1484 LKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCAD 1543
Query: 1209 GCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPG 1268
C L C L P C C EGC CD GF +G++C+P+ CGC H G Y+ P QT
Sbjct: 1544 TCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLI- 1602
Query: 1269 PGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVG------------------- 1309
C C C G + C+ SC P + CQPSGG L CV
Sbjct: 1603 DNCRQQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQ 1662
Query: 1310 -------SSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQT-CG--TRPGLHRFAVLQENV 1359
+TC GDPHY +FDGR+FDF GTC YVLA T C + GL F V +N
Sbjct: 1663 GVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQ 1722
Query: 1360 AWGNGRVSVTRVITVQVANFTLRLEQRQ-WKVTVRADGEQGARGLWVGGTQAALSPG 1415
GN VS RV+TV + + + + KV V +G A + V + +++ G
Sbjct: 1723 NRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQG 1779
Score = 585 bits (1508), Expect = e-166
Identities = 320/862 (37%), Positives = 433/862 (50%), Gaps = 37/862 (4%)
Query: 505 CEGMQCAAGQRCQVV-GGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELC 563
C C G+ C ++ G+ GC STA C+A GDPHY T DG R+D GTC Y + C
Sbjct: 2045 CTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPC 2104
Query: 564 SEDDT-LPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPV 622
F+V NEHRGS+ VSY VT++ Y+HS++L+ + VD LP
Sbjct: 2105 HGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPF 2164
Query: 623 SLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADD 682
L + L + SG VV GL + +D D + L +PA + +CGLCGNYN DPADD
Sbjct: 2165 QL-DSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADD 2223
Query: 683 FLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPA-CTPGQAQHYEGDRLCGMLTKL 741
G A W++ G C + CP+ CTP Q + + G CG+++
Sbjct: 2224 LKAVGGKPA--------GWQVG-GAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISAT 2274
Query: 742 DGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPAN 801
DGP A CH + P + + C+ D C V G LC ++ Y AC G +G+WR P
Sbjct: 2275 DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDF 2334
Query: 802 CPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCG 861
CPL CPA+S YELCG +CP SC +AP C C EGCVC GFV SG CVP CG
Sbjct: 2335 CPLQCPAHSHYELCGDSCPVSCPSLSAPEGCESA-CREGCVCDAGFVLSGDTCVPVGQCG 2393
Query: 862 CTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDR 921
C G G+ + C+RRC C H VTC++ +C E C +++G+ C+
Sbjct: 2394 CLHDGRYYPLGEVFYPGPECERRCECGPGGH-VTCQEGAACGPHEECRLEDGVQACHATG 2452
Query: 922 FGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYT 981
G C +G HY++ DGR +D G+C+Y+L C F +++E G
Sbjct: 2453 CGRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGD-----L 2507
Query: 982 RAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVT 1041
+ + V G V++ + QV VD LP A G+V+V +GR+ V++T GL +
Sbjct: 2508 QRLLVTVAGQVVSLAQGQ--QVTVDGEAVALP--VAVGRVRVTAEGRNMVLQTTKGLRLL 2563
Query: 1042 YDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEE-TRPG 1100
+D +A + +PS + LCGLCGNFNG+ +DD L G A++ FG +W+ + G
Sbjct: 2564 FDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKG 2623
Query: 1101 CG-ATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLL 1159
CG P CP + +S CG L +P+GPF C + L P R CVYD C
Sbjct: 2624 CGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQ 2683
Query: 1160 PGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPV 1219
G LC +LA Y AACQAAG V PWR++ CPL CP HSHY C+ C SC L
Sbjct: 2684 KGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSG 2743
Query: 1220 PGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQE 1279
GC + C EGC CD+ F LS C+P+ CGC H G Y P + C C C
Sbjct: 2744 LTGCTTRCFEGCECDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTS-DCSERCSCSS 2802
Query: 1280 GGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVL 1339
++C+++ C P C+ + C A C S + TTFDG R VY L
Sbjct: 2803 SSGLTCQAAGCPPGRVCEVKAEARNCWAT-RGLCVLSVGANLTTFDGARGATTSPGVYEL 2861
Query: 1340 AQTCGTRPGLHRFAVLQENVAW 1361
+ C PG LQ + W
Sbjct: 2862 SSRC---PG------LQNTIPW 2874
Score = 322 bits (825), Expect = 2e-87
Identities = 195/581 (33%), Positives = 281/581 (48%), Gaps = 39/581 (6%)
Query: 506 EGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSE 565
EG C + C++ G C A C A G HY T DGR YD+ G+CSY + ++C
Sbjct: 2429 EGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHP 2488
Query: 566 DDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLS 625
FS+ + G + LVTV VSL +G+ V VD + LPV++
Sbjct: 2489 KPGDEDFSIVLEKNAAGDLQRL---LVTVAG--QVVSLAQGQQ--VTVDGEAVALPVAV- 2540
Query: 626 EGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLT 685
GR+RV G V++ GL + +D D L +S+P+ F+ ++CGLCGN+NG+ +DDF+
Sbjct: 2541 -GRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVL 2599
Query: 686 PDGALAPDAVEFASSWKLDDGDYLCEDGC-QNNCPACTPGQAQHYEGDRLCGMLTKLDGP 744
P+G+ A F ++W+ C +GC CP C + YE + CG L GP
Sbjct: 2600 PNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGP 2659
Query: 745 FAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPL 804
FA C L P + QCVYDLC G++ LCR L+AY AC G++V WR+ + CPL
Sbjct: 2660 FATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPL 2719
Query: 805 SCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGCTF 864
CPA+S Y +C C SC + + C+ R C EGC C F+ S G C+P CGCT
Sbjct: 2720 HCPAHSHYSICTRTCQGSCAALSGLTGCTTR-CFEGCECDDRFLLSQGVCIPVQDCGCTH 2778
Query: 865 QGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGT 924
G L + + C RC+C+ ++ +TC+ CP G C V+ C+ R G
Sbjct: 2779 NGRYLPVNSSLLTSD-CSERCSCSSSSG-LTCQ-AAGCPPGRVCEVKAEARNCWATR-GL 2834
Query: 925 CQGSGDPHYVSFDGRRFDFMGTCTYLLVGSC-GQNAALPAFRVLVENE--HRGSQTVSYT 981
C S + +FDG R Y L C G +P +RV+ E + H ++ V
Sbjct: 2835 CVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVGQV 2894
Query: 982 RAVRVEA-------RGVKV-AVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVR 1033
+ +GV V +R + P + L + P DG + +VR
Sbjct: 2895 HIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTP----DGSL---------LVR 2941
Query: 1034 TDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADD 1074
G+ V N +V V + +A LCG CGNF+GD +D
Sbjct: 2942 QKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTND 2982
Score = 42.7 bits (99), Expect = 0.003
Identities = 49/190 (25%), Positives = 82/190 (43%), Gaps = 23/190 (12%)
Query: 504 SCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELC 563
+C+ C G+ C+V C A + +C + TTFDG R Y + C
Sbjct: 2807 TCQAAGCPPGRVCEVKAEARNCWA-TRGLCVLSVGANLTTFDGARGATTSPGVYELSSRC 2865
Query: 564 SE-DDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLP- 621
+T+P + V A+ + + + VG V + V+LT + V V+ R LP
Sbjct: 2866 PGLQNTIPWYRVVAEVQICHGKTEA-VGQVHIFFQDGMVTLTPNKG--VWVNGLRVDLPA 2922
Query: 622 -----VSLS---EGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCG 673
VS+S +G L V Q G+ V + ++A+ + ++CG CG
Sbjct: 2923 EKLASVSVSRTPDGSLLVRQKA---------GVQVWLGANGKVAVIVSNDHAGKLCGACG 2973
Query: 674 NYNGDPADDF 683
N++GD +D+
Sbjct: 2974 NFDGDQTNDW 2983
>gi|154146262 Fc fragment of IgG binding protein [Homo sapiens]
Length = 5405
Score = 2726 bits (7067), Expect = 0.0
Identities = 1313/1313 (100%), Positives = 1313/1313 (100%)
Query: 80 GLTQEASVDLKNTGREEFLTAFLQNYQLAYSKAYPRLLISSLSESPASVSILSQADNTSK 139
GLTQEASVDLKNTGREEFLTAFLQNYQLAYSKAYPRLLISSLSESPASVSILSQADNTSK
Sbjct: 19 GLTQEASVDLKNTGREEFLTAFLQNYQLAYSKAYPRLLISSLSESPASVSILSQADNTSK 78
Query: 140 KVTVRPGESVMVNISAKAEMIGSKIFQHAVVIHSDYAISVQALNAKPDTAELTLLRPIQA 199
KVTVRPGESVMVNISAKAEMIGSKIFQHAVVIHSDYAISVQALNAKPDTAELTLLRPIQA
Sbjct: 79 KVTVRPGESVMVNISAKAEMIGSKIFQHAVVIHSDYAISVQALNAKPDTAELTLLRPIQA 138
Query: 200 LGTEYFVLTPPGTSARNVKEFAVVAGAAGASVSVTLKGSVTFNGKFYPAGDVLRVTLQPY 259
LGTEYFVLTPPGTSARNVKEFAVVAGAAGASVSVTLKGSVTFNGKFYPAGDVLRVTLQPY
Sbjct: 139 LGTEYFVLTPPGTSARNVKEFAVVAGAAGASVSVTLKGSVTFNGKFYPAGDVLRVTLQPY 198
Query: 260 NVAQLQSSVDLSGSKVTASSPVAVLSGHSCAQKHTTCNHVVEQLLPTSAWGTHYVVPTLA 319
NVAQLQSSVDLSGSKVTASSPVAVLSGHSCAQKHTTCNHVVEQLLPTSAWGTHYVVPTLA
Sbjct: 199 NVAQLQSSVDLSGSKVTASSPVAVLSGHSCAQKHTTCNHVVEQLLPTSAWGTHYVVPTLA 258
Query: 320 SQSRYDLAFVVASQATKLTYNHGGITGSRGLQAGDVVEFEVRPSWPLYLSANVGIQVLLF 379
SQSRYDLAFVVASQATKLTYNHGGITGSRGLQAGDVVEFEVRPSWPLYLSANVGIQVLLF
Sbjct: 259 SQSRYDLAFVVASQATKLTYNHGGITGSRGLQAGDVVEFEVRPSWPLYLSANVGIQVLLF 318
Query: 380 GTGAIRNEVTYDPYLVLIPDVAAYCPAYVVKSVPGCEGVALVVAQTKAISGLTIDGHAVG 439
GTGAIRNEVTYDPYLVLIPDVAAYCPAYVVKSVPGCEGVALVVAQTKAISGLTIDGHAVG
Sbjct: 319 GTGAIRNEVTYDPYLVLIPDVAAYCPAYVVKSVPGCEGVALVVAQTKAISGLTIDGHAVG 378
Query: 440 AKLTWEAVPGSEFSYAEVELGTADMIHTAEATTNLGLLTFGLAKAIGYATAADCGRTVLS 499
AKLTWEAVPGSEFSYAEVELGTADMIHTAEATTNLGLLTFGLAKAIGYATAADCGRTVLS
Sbjct: 379 AKLTWEAVPGSEFSYAEVELGTADMIHTAEATTNLGLLTFGLAKAIGYATAADCGRTVLS 438
Query: 500 PVEPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTM 559
PVEPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTM
Sbjct: 439 PVEPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTM 498
Query: 560 VELCSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSR 619
VELCSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSR
Sbjct: 499 VELCSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSR 558
Query: 620 LPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDP 679
LPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDP
Sbjct: 559 LPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDP 618
Query: 680 ADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLT 739
ADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLT
Sbjct: 619 ADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLT 678
Query: 740 KLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSP 799
KLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSP
Sbjct: 679 KLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSP 738
Query: 800 ANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASS 859
ANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASS
Sbjct: 739 ANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASS 798
Query: 860 CGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYP 919
CGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYP
Sbjct: 799 CGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYP 858
Query: 920 DRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVS 979
DRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVS
Sbjct: 859 DRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVS 918
Query: 980 YTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLT 1039
YTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLT
Sbjct: 919 YTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLT 978
Query: 1040 VTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRP 1099
VTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRP
Sbjct: 979 VTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRP 1038
Query: 1100 GCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLL 1159
GCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLL
Sbjct: 1039 GCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLL 1098
Query: 1160 PGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPV 1219
PGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPV
Sbjct: 1099 PGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPV 1158
Query: 1220 PGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQE 1279
PGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQE
Sbjct: 1159 PGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQE 1218
Query: 1280 GGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVL 1339
GGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVL
Sbjct: 1219 GGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVL 1278
Query: 1340 AQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTV 1392
AQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTV
Sbjct: 1279 AQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTV 1331
Score = 907 bits (2344), Expect = 0.0
Identities = 446/899 (49%), Positives = 557/899 (61%), Gaps = 22/899 (2%)
Query: 505 CEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVEL-C 563
C G+ C + C+ GG+ C+ A C GDPHY +FDGR++D GTC+Y + C
Sbjct: 2846 CHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGC 2905
Query: 564 SEDDT--LPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLP 621
T L F+V KN++RG+ VSYV +VTV A ++S+ + E+G V V+ + LP
Sbjct: 2906 PGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALP 2965
Query: 622 VSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPAD 681
VS+++GR+ V Q +A++ FGL V+YDW+ ++ ++LP+ + VCGLCGN + +P +
Sbjct: 2966 VSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNN 3025
Query: 682 DFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTK- 740
D + P+G LAP + SW+ D LC D C+ +CP C + + YEG CG L
Sbjct: 3026 DQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPG 3085
Query: 741 LDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPA 800
GPF CH + P F + CV D+C+ GG+R LC+ L++Y AC G+ + DWR+
Sbjct: 3086 TGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV 3145
Query: 801 NCPLSCPANSRYELCGPACPTSCNGAA---APSNCSGRPCVEGCVCLPGFVASGGACVPA 857
C ++CP NS YE+CGP CP SC A P+ C G PCVEGC C GFV S CVP
Sbjct: 3146 GCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEG-PCVEGCQCDAGFVLSADRCVPL 3204
Query: 858 SS-CGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSV-QNGLL 915
++ CGC G G E WAD C + C C + C SC GE C + +G
Sbjct: 3205 NNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPA-SCGLGEVCGLLPSGQH 3263
Query: 916 GCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSC-GQNAALPAFRVLVENEHRG 974
GC P CQ GDPHYV+ DG RFDF GTC YLL C G F V V NEHRG
Sbjct: 3264 GCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG 3323
Query: 975 SQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRT 1034
SQ VSYTR+V ++ + + +P ++ VD V LPFQ D + G D VV T
Sbjct: 3324 SQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQL-DSLLHAHLSGADVVVTT 3382
Query: 1035 DFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQ 1094
GL++ +D ++ V +VP++YA +LCGLCGN+N DPADDL GG A WQ
Sbjct: 3383 TSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPAG--------WQ 3434
Query: 1095 EETRPGCGATEPGDCPKLDSLVAQQ-LQSKNECGILADPKGPFRECHSKLDPQGAVRDCV 1153
GCG CP + Q+ + CG+++ GP CH + P + C+
Sbjct: 3435 VGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCL 3494
Query: 1154 YDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLS 1213
D C + G G LC A+ATY AACQAAGA + WR + CP CP HSHYE C CP S
Sbjct: 3495 LDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGS 3554
Query: 1214 CGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDS 1273
C L P GC S C EGCVCD GF LSG++C+P+ CGC+H Y+P GQTFYPGPGCDS
Sbjct: 3555 CPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDS 3614
Query: 1274 LCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMG 1333
LC C+EGG VSCE SSCGPHE C+PSGGSLGCVAVGS+TCQASGDPHYTTFDG RFDFMG
Sbjct: 3615 LCRCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGHRFDFMG 3674
Query: 1334 TCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTV 1392
TCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTV
Sbjct: 3675 TCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTV 3733
Score = 904 bits (2336), Expect = 0.0
Identities = 445/899 (49%), Positives = 557/899 (61%), Gaps = 22/899 (2%)
Query: 505 CEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVEL-C 563
C G+ C + C+ GG+ C+ A C GDPHY +FDGR++D GTC+Y + C
Sbjct: 1645 CHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGC 1704
Query: 564 SEDDT--LPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLP 621
T L F+V KN++RG+ VSYV +VTV A ++S+ + E+G V V+ + LP
Sbjct: 1705 PGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALP 1764
Query: 622 VSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPAD 681
VS+++GR+ V Q +A++ FGL V+YDW+ ++ ++LP+ + VCGLCGN + +P +
Sbjct: 1765 VSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNN 1824
Query: 682 DFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTK- 740
D + P+G LAP + SW+ D LC D C+ +CP C + + YEG CG L
Sbjct: 1825 DQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPG 1884
Query: 741 LDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPA 800
GPF CH + P F + CV D+C+ GG+R LC+ L++Y AC G+ + DWR+
Sbjct: 1885 TGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV 1944
Query: 801 NCPLSCPANSRYELCGPACPTSCNGAA---APSNCSGRPCVEGCVCLPGFVASGGACVPA 857
C ++CP NS YE+CG CP SC A P+ C G PCVEGC C GFV S CVP
Sbjct: 1945 GCEITCPENSHYEVCGSPCPASCPSPAPLTTPAVCEG-PCVEGCQCDAGFVLSADRCVPL 2003
Query: 858 SS-CGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSV-QNGLL 915
++ CGC G G E WAD C + C C + C SC GE C + +G
Sbjct: 2004 NNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPA-SCGLGEVCGLLPSGQH 2062
Query: 916 GCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSC-GQNAALPAFRVLVENEHRG 974
GC P CQ GDPHYV+ DG RF+F GTC YLL C G F V V NEHRG
Sbjct: 2063 GCQPVSTAECQAWGDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG 2122
Query: 975 SQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRT 1034
SQ VSYTR+V ++ + + +P ++ VD V LPFQ D + G D VV T
Sbjct: 2123 SQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQL-DSLLHAHLSGADVVVTT 2181
Query: 1035 DFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQ 1094
GL++ +D ++ V +VP++YA +LCGLCGN+N DPADDL GG A WQ
Sbjct: 2182 TSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPAG--------WQ 2233
Query: 1095 EETRPGCGATEPGDCPKLDSLVAQQ-LQSKNECGILADPKGPFRECHSKLDPQGAVRDCV 1153
GCG CP + Q+ + CG+++ GP CH + P + C+
Sbjct: 2234 VGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCL 2293
Query: 1154 YDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLS 1213
D C + G G LC A+ATY AACQAAGA + WR + CP CP HSHYE C CP S
Sbjct: 2294 LDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGS 2353
Query: 1214 CGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDS 1273
C L P GC S C EGCVCD GF LSG++C+P+ CGC+H Y+P GQTFYPGPGCDS
Sbjct: 2354 CPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDS 2413
Query: 1274 LCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMG 1333
LC C+EGG VSCE SSCGPHE C+PSGGSLGCVAVGS+TCQASGDPHYTTFDGRRFDFMG
Sbjct: 2414 LCRCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGRRFDFMG 2473
Query: 1334 TCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTV 1392
TCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTV
Sbjct: 2474 TCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTV 2532
Score = 754 bits (1948), Expect = 0.0
Identities = 388/914 (42%), Positives = 517/914 (56%), Gaps = 31/914 (3%)
Query: 505 CEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVEL-C 563
C G+ C + C+ GG+ C+ A C GDPHY +FDGR++D GTC+Y + C
Sbjct: 4047 CHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGC 4106
Query: 564 SEDDT--LPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLP 621
T L F+V KN++RG+ VSYV +VTV A ++S+ + E+G V V+ + LP
Sbjct: 4107 PGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALP 4166
Query: 622 VSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPAD 681
VS+++GR+ V Q +A++ FGL V+YDW+ ++ ++LP+ + VCGLCGN + +P +
Sbjct: 4167 VSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNN 4226
Query: 682 DFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTK- 740
D + P+G LAP + SW+ D LC D C+ +CP C + + YEG CG L+
Sbjct: 4227 DQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLSSG 4286
Query: 741 LDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPA 800
GPF CH + P F + CV D+C+ GG+R LC+ L++Y AC G+ + DWR+
Sbjct: 4287 TGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV 4346
Query: 801 NCPLSCPANSRYELCGPACPTSCNGAA---APSNCSGRPCVEGCVCLPGFVASGGACVPA 857
C ++CP NS YE+CGP CP SC A P+ C G PCVEGC C GFV S CVP
Sbjct: 4347 GCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEG-PCVEGCQCDAGFVLSADRCVPL 4405
Query: 858 SS-CGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSV-QNGLL 915
++ CGC G G E WAD C + C C + C SC GE C + +G
Sbjct: 4406 NNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPA-SCGLGEVCGLLPSGQH 4464
Query: 916 GCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSC-GQNAALPAFRVLVENEHRG 974
GC P CQ GDPHYV+ DG RFDF GTC YLL C G F V V NEHRG
Sbjct: 4465 GCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG 4524
Query: 975 SQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRT 1034
SQ VSYTR+V ++ + + +P ++ VD V LPFQ D + G D VV T
Sbjct: 4525 SQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQL-DSLLHAHLSGADVVVTT 4583
Query: 1035 DFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQ 1094
GL++ +D ++ V +VP++YA +LCGLCGN+N DPADDL GG A WQ
Sbjct: 4584 TSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAG--------WQ 4635
Query: 1095 EETRPGCGATEPGDCPKLDSLVAQQ-LQSKNECGILADPKGPFRECHSKLDPQGAVRDCV 1153
GCG CP + Q+ + CG+++ GP CH + P + C+
Sbjct: 4636 VGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCL 4695
Query: 1154 YDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLS 1213
D C + G G LC A+ATY AACQAAGA + WR + CPL CP HSHYE C CP+S
Sbjct: 4696 LDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVS 4755
Query: 1214 CGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDS 1273
C L P GC S C EGCVCD GF LSG++C+P+ CGC+H G Y+P G+ FYPGP C+
Sbjct: 4756 CPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECER 4815
Query: 1274 LCHCQEGGLVSC-ESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFM 1332
C C GG V+C E ++CGPHE C+ G C A G C A+G HY T DGR +D
Sbjct: 4816 RCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLH 4875
Query: 1333 GTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTV 1392
G+C YVLAQ C +PG F+++ E A G+ + + V VA + L Q Q +VTV
Sbjct: 4876 GSCSYVLAQVCHPKPGDEDFSIVLEKNAAGD-----LQRLLVTVAGQVVSLAQGQ-QVTV 4929
Query: 1393 RADGEQGARGLWVG 1406
DGE A + VG
Sbjct: 4930 --DGEAVALPVAVG 4941
Score = 748 bits (1930), Expect = 0.0
Identities = 387/915 (42%), Positives = 492/915 (53%), Gaps = 55/915 (6%)
Query: 504 SCEGMQ-CAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVEL 562
+C Q C AG+RC V G GC + C+ GDPHY +FDGRR+D MGTC+Y +V
Sbjct: 834 TCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGS 893
Query: 563 CSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPV 622
C ++ LPAF V +NEHRGS+ VSY V V A V++ R G VLVD+ LP
Sbjct: 894 CGQNAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPF 953
Query: 623 SLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADD 682
++G+++V++ G AVV FGL VTYDW+ ++ +P+ + + +CGLCGN+NGDPADD
Sbjct: 954 QAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADD 1013
Query: 683 FLTPDGALAPDAVEFASSWKLDDGDYLCEDGC----QNNCPACTPGQAQHYEGDRLCGML 738
G A +A+ F +SW+ + GC +CP AQ + CG+L
Sbjct: 1014 LALRGGGQAANALAFGNSWQEET-----RPGCGATEPGDCPKLDSLVAQQLQSKNECGIL 1068
Query: 739 TKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRS 798
GPF CH LDP+ + CVYD C++ G+ LC L+ YA AC G +V WRS
Sbjct: 1069 ADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRS 1128
Query: 799 PANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPAS 858
CPLSCP +S YE C CP SC P C G C EGCVC GF SG +C+P +
Sbjct: 1129 EELCPLSCPPHSHYEACSYGCPLSCGDLPVPGGC-GSECHEGCVCDEGFALSGESCLPLA 1187
Query: 859 SCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCY 918
SCGC QG PGQ + C C C V+C + SC E C G LGC
Sbjct: 1188 SCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGG-LVSC-ESSSCGPHEACQPSGGSLGCV 1245
Query: 919 PDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTV 978
TCQ SGDPHY +FDGRRFDFMGTC Y+L +CG L F VL EN G+ V
Sbjct: 1246 AVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRV 1305
Query: 979 SYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGL 1038
S TR + V+ + + + +V V+ V LP A+GQ++ + G D V+ TDFGL
Sbjct: 1306 SVTRVITVQVANFTLRLEQRQ-WKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGL 1364
Query: 1039 TVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETR 1098
V YD V VP +Y + +CGLCGN+NGDP DD G QA NA FGNSW EE
Sbjct: 1365 RVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSW-EEVV 1423
Query: 1099 PGCGATEPGDCP----------KLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGA 1148
P P CP K + ++ Q + CG+L+ P GP CH +DPQG
Sbjct: 1424 PDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGP 1483
Query: 1149 VRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSY 1208
++DC++D CL G LC + Y +ACQAAG V PWR+E CP+ CPP+SHYE C+
Sbjct: 1484 LKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCAD 1543
Query: 1209 GCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPG 1268
C L C L P C C EGC CD GF +G++C+P+ CGC H G Y+ P QT
Sbjct: 1544 TCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLI- 1602
Query: 1269 PGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVG------------------- 1309
C C C G + C+ SC P + CQPSGG L CV
Sbjct: 1603 DNCRQQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQ 1662
Query: 1310 -------SSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQT-CG--TRPGLHRFAVLQENV 1359
+TC GDPHY +FDGR+FDF GTC YVLA T C + GL F V +N
Sbjct: 1663 GVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQ 1722
Query: 1360 AWGNGRVSVTRVITV 1374
GN VS RV+TV
Sbjct: 1723 NRGNPAVSYVRVVTV 1737
Score = 685 bits (1767), Expect = 0.0
Identities = 369/912 (40%), Positives = 469/912 (51%), Gaps = 58/912 (6%)
Query: 505 CEGMQCAAGQRCQVV-GGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELC 563
C C G+ C ++ G+ GC STA C+A GDPHY T DG R+D GTC Y + C
Sbjct: 3244 CTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPC 3303
Query: 564 SEDDT-LPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPV 622
F+V NEHRGS+ VSY VT++ Y+HS++L+ + VD LP
Sbjct: 3304 HGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPF 3363
Query: 623 SLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADD 682
L + L + SG VV GL + +D D + L +PA + +CGLCGNYN DPADD
Sbjct: 3364 QL-DSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADD 3422
Query: 683 FLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPA-CTPGQAQHYEGDRLCGMLTKL 741
G A W++ G C + CP+ CTP Q + + G CG+++
Sbjct: 3423 LKAVGGKPA--------GWQVG-GAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISAT 3473
Query: 742 DGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPAN 801
DGP A CH + P + + C+ D C V G LC ++ Y AC G + +WR P
Sbjct: 3474 DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDF 3533
Query: 802 CPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCG 861
CP CPA+S YELCG +CP SC +AP C C EGCVC GFV SG CVP CG
Sbjct: 3534 CPFQCPAHSHYELCGDSCPGSCPSLSAPEGCESA-CREGCVCDAGFVLSGDTCVPVGQCG 3592
Query: 862 CTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDR 921
C GQ + C C C +V+C + SC E C G LGC
Sbjct: 3593 CLHDDRYYPLGQTFYPGPGCDSLCRCREGG-EVSC-EPSSCGPHETCRPSGGSLGCVAVG 3650
Query: 922 FGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYT 981
TCQ SGDPHY +FDG RFDFMGTC Y+L +CG L F VL EN G+ VS T
Sbjct: 3651 STTCQASGDPHYTTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVT 3710
Query: 982 RAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVT 1041
R + V+ + + + +V V+ V LP A+GQ++ + G D V+ TDFGL V
Sbjct: 3711 RVITVQVANFTLRLEQRQ-WKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVA 3769
Query: 1042 YDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGC 1101
YD V VP +Y + +CGLCGN+NGDP DD G QA NA FGNSW EE P
Sbjct: 3770 YDLVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSW-EEVVPDS 3828
Query: 1102 GATEPGDCP----------KLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRD 1151
P CP K + ++ Q + CG+L+ P GP CH +DPQG ++D
Sbjct: 3829 PCLPPPTCPPGSAGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKD 3888
Query: 1152 CVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCP 1211
C++D CL G LC + Y +ACQAAG V PWR+E CP+ CP +SHYE C+ C
Sbjct: 3889 CIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRNETFCPMECPQNSHYELCADTCS 3948
Query: 1212 LSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGC 1271
L C L P C C EGC CD GF +G++C+P+ CGC H G Y+ P QT C
Sbjct: 3949 LGCSALSAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLI-DNC 4007
Query: 1272 DSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVG---------------------- 1309
C C G +V C+ SC P + CQPSGG L CV
Sbjct: 4008 RQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVC 4067
Query: 1310 ----SSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQT-CG--TRPGLHRFAVLQENVAWG 1362
+TC GDPHY +FDGR+FDF GTC YVLA T C + GL F V +N G
Sbjct: 4068 LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRG 4127
Query: 1363 NGRVSVTRVITV 1374
N VS RV+TV
Sbjct: 4128 NPAVSYVRVVTV 4139
Score = 683 bits (1762), Expect = 0.0
Identities = 368/912 (40%), Positives = 470/912 (51%), Gaps = 58/912 (6%)
Query: 505 CEGMQCAAGQRCQVV-GGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELC 563
C C G+ C ++ G+ GC STA C+A GDPHY T DG R++ GTC Y + C
Sbjct: 2043 CTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFNFQGTCEYLLSAPC 2102
Query: 564 SEDDT-LPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPV 622
F+V NEHRGS+ VSY VT++ Y+HS++L+ + VD LP
Sbjct: 2103 HGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPF 2162
Query: 623 SLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADD 682
L + L + SG VV GL + +D D + L +PA + +CGLCGNYN DPADD
Sbjct: 2163 QL-DSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADD 2221
Query: 683 FLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPA-CTPGQAQHYEGDRLCGMLTKL 741
G A W++ G C + CP+ CTP Q + + G CG+++
Sbjct: 2222 LKAVGGKPA--------GWQVG-GAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISAT 2272
Query: 742 DGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPAN 801
DGP A CH + P + + C+ D C V G LC ++ Y AC G + +WR P
Sbjct: 2273 DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDF 2332
Query: 802 CPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCG 861
CP CPA+S YELCG +CP SC +AP C C EGCVC GFV SG CVP CG
Sbjct: 2333 CPFQCPAHSHYELCGDSCPGSCPSLSAPEGCESA-CREGCVCDAGFVLSGDTCVPVGQCG 2391
Query: 862 CTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDR 921
C GQ + C C C +V+C + SC E C G LGC
Sbjct: 2392 CLHDDRYYPLGQTFYPGPGCDSLCRCREGG-EVSC-EPSSCGPHETCRPSGGSLGCVAVG 2449
Query: 922 FGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYT 981
TCQ SGDPHY +FDGRRFDFMGTC Y+L +CG L F VL EN G+ VS T
Sbjct: 2450 STTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVT 2509
Query: 982 RAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVT 1041
R + V+ + + + +V V+ V LP A+GQ++ + G D V+ TDFGL V
Sbjct: 2510 RVITVQVANFTLRLEQRQ-WKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVA 2568
Query: 1042 YDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGC 1101
YD V VP +Y + +CGLCGN+NGDP DD G QA NA FGNSW EE P
Sbjct: 2569 YDLVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSW-EEVVPDS 2627
Query: 1102 GATEPGDCP----------KLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRD 1151
P CP + + ++ Q + CG+L+ P GP CH +DPQG ++D
Sbjct: 2628 PCLPPPTCPPGSEGCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKD 2687
Query: 1152 CVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCP 1211
C++D CL G LC + Y +ACQAAG V PWR+E CP+ CP +SHYE C+ C
Sbjct: 2688 CIFDLCLGGGNLSILCSNIHAYVSACQAAGGQVEPWRNETFCPMECPQNSHYELCADTCS 2747
Query: 1212 LSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGC 1271
L C L P C C EGC CD GF +G++C+P+ CGC H G Y+ P QT C
Sbjct: 2748 LGCSALSAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGAYYEPEQTVLI-DNC 2806
Query: 1272 DSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVG---------------------- 1309
C C G +V C+ SC P + CQPSGG L CV
Sbjct: 2807 RQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSCVNKDPCHGVTCRPQETCKEQGGQGVC 2866
Query: 1310 ----SSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQT-CG--TRPGLHRFAVLQENVAWG 1362
+TC GDPHY +FDGR+FDF GTC YVLA T C + GL F V +N G
Sbjct: 2867 LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRG 2926
Query: 1363 NGRVSVTRVITV 1374
N VS RV+TV
Sbjct: 2927 NPAVSYVRVVTV 2938
Score = 682 bits (1760), Expect = 0.0
Identities = 376/940 (40%), Positives = 500/940 (53%), Gaps = 50/940 (5%)
Query: 502 EPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVE 561
E SCE C + C+ GG GCVA + C+A GDPHYTTFDGRR+D MGTC Y + +
Sbjct: 2422 EVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGRRFDFMGTCVYVLAQ 2481
Query: 562 LCSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLP 621
C L F+V +N G+ RVS ++TV+ + ++ L + + V V+ +LP
Sbjct: 2482 TCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQ-WKVTVNGVDMKLP 2540
Query: 622 VSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPAD 681
V L+ G++R Q G V+E FGL V YD + +++P + +CGLCGNYNGDP D
Sbjct: 2541 VVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGNYNGDPKD 2600
Query: 682 DFLTPDGALAPDAVEFASSWK--LDDGDYL----CEDGCQNNCPA--CTPGQAQHYEGDR 733
DF P+G+ A +A EF +SW+ + D L C G + P+ C P + Y+ +
Sbjct: 2601 DFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSEGCIPSEECPPELEKKYQKEE 2660
Query: 734 LCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISV 793
CG+L+ GP + CH +DP+ L+ C++DLC+ GG LC + AY AC G V
Sbjct: 2661 FCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGQV 2720
Query: 794 GDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGA 853
WR+ CP+ CP NS YELC C C+ +AP C C EGC C GF+ +G A
Sbjct: 2721 EPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPD-GCAEGCQCDSGFLYNGQA 2779
Query: 854 CVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCN----GATHQVTCRDKQSC-PAG--- 905
CVP CGC G P Q V D C+++CTC+ + +C+ Q C P+G
Sbjct: 2780 CVPIQQCGCYHNGAYYEPEQTVLIDN-CRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGIL 2838
Query: 906 ----------------ERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTY 949
E C Q G C P+ TC GDPHY SFDGR+FDF GTC Y
Sbjct: 2839 SCVNKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNY 2898
Query: 950 LL--VGSCG-QNAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVD 1006
+L G G L F V +N++RG+ VSY R V V A G +++ ++ G+V V+
Sbjct: 2899 VLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVN 2958
Query: 1007 DVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGN 1066
VL LP ADG++ V + A++ DFGL V+YDWN RV +PSSY A+CGLCGN
Sbjct: 2959 GVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGN 3018
Query: 1067 FNGDPADDLALRGGGQAANALAFGNSWQEE-TRPGCGATEPGDCPKLDSLVAQQLQSKNE 1125
+ +P +D G A + +G SW+ P C G CP +Q +
Sbjct: 3019 MDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGF 3078
Query: 1126 CGILA-DPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATV 1184
CG LA GPF CH+ + P+ + CV D C+ G LC ALA+Y AACQAAG +
Sbjct: 3079 CGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVI 3138
Query: 1185 HPWRSEELCPLSCPPHSHYEACSYGCPLSC---GDLPVPGGCGSECHEGCVCDEGFALSG 1241
WR++ C ++CP +SHYE C CP SC L P C C EGC CD GF LS
Sbjct: 3139 EDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSA 3198
Query: 1242 ESCLPLAS-CGCVHQGTYHPPGQTFYPGPGCDSLCHC-QEGGLVSCESSSCGPHEAC--Q 1297
+ C+PL + CGC GTYH G F+ C C C GG + C +SCG E C
Sbjct: 3199 DRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLL 3258
Query: 1298 PSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRP-GLHRFAVLQ 1356
PS G GC V ++ CQA GDPHY T DG RFDF GTC Y+L+ C P G F V
Sbjct: 3259 PS-GQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTV 3317
Query: 1357 ENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVRADG 1396
N G+ VS TR +T+Q+ N +L L R W ++ DG
Sbjct: 3318 ANEHRGSQAVSYTRSVTLQIYNHSLTLSAR-WPRKLQVDG 3356
Score = 679 bits (1751), Expect = 0.0
Identities = 374/940 (39%), Positives = 499/940 (53%), Gaps = 50/940 (5%)
Query: 502 EPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVE 561
E SCE C + C+ GG GCVA + C+A GDPHYTTFDG R+D MGTC Y + +
Sbjct: 3623 EVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGHRFDFMGTCVYVLAQ 3682
Query: 562 LCSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLP 621
C L F+V +N G+ RVS ++TV+ + ++ L + + V V+ +LP
Sbjct: 3683 TCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQ-WKVTVNGVDMKLP 3741
Query: 622 VSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPAD 681
V L+ G++R Q G V+E FGL V YD + +++P + +CGLCGNYNGDP D
Sbjct: 3742 VVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGNYNGDPKD 3801
Query: 682 DFLTPDGALAPDAVEFASSWK--LDDGDYL----CEDGCQNNCPA--CTPGQAQHYEGDR 733
DF P+G+ A +A EF +SW+ + D L C G P+ C P + Y+ +
Sbjct: 3802 DFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSAGCIPSDKCPPELEKKYQKEE 3861
Query: 734 LCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISV 793
CG+L+ GP + CH +DP+ L+ C++DLC+ GG LC + AY AC G V
Sbjct: 3862 FCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHV 3921
Query: 794 GDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGA 853
WR+ CP+ CP NS YELC C C+ +AP C C EGC C GF+ +G A
Sbjct: 3922 EPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPD-GCAEGCQCDSGFLYNGQA 3980
Query: 854 CVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCN----GATHQVTCRDKQSC-PAG--- 905
CVP CGC G+ P Q V D C+++CTC+ + +C+ Q C P+G
Sbjct: 3981 CVPIQQCGCYHNGVYYEPEQTVLIDN-CRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGIL 4039
Query: 906 ----------------ERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTY 949
E C Q G C P+ TC GDPHY SFDGR+FDF GTC Y
Sbjct: 4040 SCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNY 4099
Query: 950 LL--VGSCG-QNAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVD 1006
+L G G L F V +N++RG+ VSY R V V A G +++ ++ G+V V+
Sbjct: 4100 VLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVN 4159
Query: 1007 DVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGN 1066
VL LP ADG++ V + A++ DFGL V+YDWN RV +PSSY A+CGLCGN
Sbjct: 4160 GVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGN 4219
Query: 1067 FNGDPADDLALRGGGQAANALAFGNSWQEE-TRPGCGATEPGDCPKLDSLVAQQLQSKNE 1125
+ +P +D G A + +G SW+ P C G CP +Q +
Sbjct: 4220 MDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGF 4279
Query: 1126 CGILAD-PKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATV 1184
CG L+ GPF CH+ + P+ + CV D C+ G LC ALA+Y AACQAAG +
Sbjct: 4280 CGPLSSGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVI 4339
Query: 1185 HPWRSEELCPLSCPPHSHYEACSYGCPLSC---GDLPVPGGCGSECHEGCVCDEGFALSG 1241
WR++ C ++CP +SHYE C CP SC L P C C EGC CD GF LS
Sbjct: 4340 EDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSA 4399
Query: 1242 ESCLPLAS-CGCVHQGTYHPPGQTFYPGPGCDSLCHC-QEGGLVSCESSSCGPHEAC--Q 1297
+ C+PL + CGC GTYH G F+ C C C GG + C +SCG E C
Sbjct: 4400 DRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLL 4459
Query: 1298 PSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRP-GLHRFAVLQ 1356
PS G GC V ++ CQA GDPHY T DG RFDF GTC Y+L+ C P G F V
Sbjct: 4460 PS-GQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTV 4518
Query: 1357 ENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVRADG 1396
N G+ VS TR +T+Q+ N +L L R W ++ DG
Sbjct: 4519 ANEHRGSQAVSYTRSVTLQIYNHSLTLSAR-WPRKLQVDG 4557
Score = 585 bits (1508), Expect = e-166
Identities = 320/862 (37%), Positives = 433/862 (50%), Gaps = 37/862 (4%)
Query: 505 CEGMQCAAGQRCQVV-GGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELC 563
C C G+ C ++ G+ GC STA C+A GDPHY T DG R+D GTC Y + C
Sbjct: 4445 CTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPC 4504
Query: 564 SEDDT-LPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPV 622
F+V NEHRGS+ VSY VT++ Y+HS++L+ + VD LP
Sbjct: 4505 HGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPF 4564
Query: 623 SLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADD 682
L + L + SG VV GL + +D D + L +PA + +CGLCGNYN DPADD
Sbjct: 4565 QL-DSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADD 4623
Query: 683 FLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPA-CTPGQAQHYEGDRLCGMLTKL 741
G A W++ G C + CP+ CTP Q + + G CG+++
Sbjct: 4624 LKAVGGKPA--------GWQVG-GAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISAT 4674
Query: 742 DGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPAN 801
DGP A CH + P + + C+ D C V G LC ++ Y AC G +G+WR P
Sbjct: 4675 DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDF 4734
Query: 802 CPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCG 861
CPL CPA+S YELCG +CP SC +AP C C EGCVC GFV SG CVP CG
Sbjct: 4735 CPLQCPAHSHYELCGDSCPVSCPSLSAPEGCESA-CREGCVCDAGFVLSGDTCVPVGQCG 4793
Query: 862 CTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDR 921
C G G+ + C+RRC C H VTC++ +C E C +++G+ C+
Sbjct: 4794 CLHDGRYYPLGEVFYPGPECERRCECGPGGH-VTCQEGAACGPHEECRLEDGVQACHATG 4852
Query: 922 FGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYT 981
G C +G HY++ DGR +D G+C+Y+L C F +++E G
Sbjct: 4853 CGRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGD-----L 4907
Query: 982 RAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVT 1041
+ + V G V++ + QV VD LP A G+V+V +GR+ V++T GL +
Sbjct: 4908 QRLLVTVAGQVVSLAQGQ--QVTVDGEAVALP--VAVGRVRVTAEGRNMVLQTTKGLRLL 4963
Query: 1042 YDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEE-TRPG 1100
+D +A + +PS + LCGLCGNFNG+ +DD L G A++ FG +W+ + G
Sbjct: 4964 FDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKG 5023
Query: 1101 CG-ATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLL 1159
CG P CP + +S CG L +P+GPF C + L P R CVYD C
Sbjct: 5024 CGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQ 5083
Query: 1160 PGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPV 1219
G LC +LA Y AACQAAG V PWR++ CPL CP HSHY C+ C SC L
Sbjct: 5084 KGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSG 5143
Query: 1220 PGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQE 1279
GC + C EGC CD+ F LS C+P+ CGC H G Y P + C C C
Sbjct: 5144 LTGCTTRCFEGCECDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTS-DCSERCSCSS 5202
Query: 1280 GGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVL 1339
++C+++ C P C+ + C A C S + TTFDG R VY L
Sbjct: 5203 SSGLTCQAAGCPPGRVCEVKAEARNCWAT-RGLCVLSVGANLTTFDGARGATTSPGVYEL 5261
Query: 1340 AQTCGTRPGLHRFAVLQENVAW 1361
+ C PG LQ + W
Sbjct: 5262 SSRC---PG------LQNTIPW 5274
Score = 322 bits (825), Expect = 2e-87
Identities = 195/581 (33%), Positives = 281/581 (48%), Gaps = 39/581 (6%)
Query: 506 EGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSE 565
EG C + C++ G C A C A G HY T DGR YD+ G+CSY + ++C
Sbjct: 4829 EGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHP 4888
Query: 566 DDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLS 625
FS+ + G + LVTV VSL +G+ V VD + LPV++
Sbjct: 4889 KPGDEDFSIVLEKNAAGDLQRL---LVTVAG--QVVSLAQGQQ--VTVDGEAVALPVAV- 4940
Query: 626 EGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLT 685
GR+RV G V++ GL + +D D L +S+P+ F+ ++CGLCGN+NG+ +DDF+
Sbjct: 4941 -GRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVL 4999
Query: 686 PDGALAPDAVEFASSWKLDDGDYLCEDGC-QNNCPACTPGQAQHYEGDRLCGMLTKLDGP 744
P+G+ A F ++W+ C +GC CP C + YE + CG L GP
Sbjct: 5000 PNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGP 5059
Query: 745 FAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPL 804
FA C L P + QCVYDLC G++ LCR L+AY AC G++V WR+ + CPL
Sbjct: 5060 FATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPL 5119
Query: 805 SCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGCTF 864
CPA+S Y +C C SC + + C+ R C EGC C F+ S G C+P CGCT
Sbjct: 5120 HCPAHSHYSICTRTCQGSCAALSGLTGCTTR-CFEGCECDDRFLLSQGVCIPVQDCGCTH 5178
Query: 865 QGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGT 924
G L + + C RC+C+ ++ +TC+ CP G C V+ C+ R G
Sbjct: 5179 NGRYLPVNSSLLTSD-CSERCSCSSSSG-LTCQ-AAGCPPGRVCEVKAEARNCWATR-GL 5234
Query: 925 CQGSGDPHYVSFDGRRFDFMGTCTYLLVGSC-GQNAALPAFRVLVENE--HRGSQTVSYT 981
C S + +FDG R Y L C G +P +RV+ E + H ++ V
Sbjct: 5235 CVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVGQV 5294
Query: 982 RAVRVEA-------RGVKV-AVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVR 1033
+ +GV V +R + P + L + P DG + +VR
Sbjct: 5295 HIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTP----DGSL---------LVR 5341
Query: 1034 TDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADD 1074
G+ V N +V V + +A LCG CGNF+GD +D
Sbjct: 5342 QKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTND 5382
Score = 42.7 bits (99), Expect = 0.003
Identities = 49/190 (25%), Positives = 82/190 (43%), Gaps = 23/190 (12%)
Query: 504 SCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELC 563
+C+ C G+ C+V C A + +C + TTFDG R Y + C
Sbjct: 5207 TCQAAGCPPGRVCEVKAEARNCWA-TRGLCVLSVGANLTTFDGARGATTSPGVYELSSRC 5265
Query: 564 SE-DDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLP- 621
+T+P + V A+ + + + VG V + V+LT + V V+ R LP
Sbjct: 5266 PGLQNTIPWYRVVAEVQICHGKTEA-VGQVHIFFQDGMVTLTPNKG--VWVNGLRVDLPA 5322
Query: 622 -----VSLS---EGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCG 673
VS+S +G L V Q G+ V + ++A+ + ++CG CG
Sbjct: 5323 EKLASVSVSRTPDGSLLVRQKA---------GVQVWLGANGKVAVIVSNDHAGKLCGACG 5373
Query: 674 NYNGDPADDF 683
N++GD +D+
Sbjct: 5374 NFDGDQTNDW 5383
>gi|239757282 PREDICTED: similar to Fc fragment of IgG binding protein
[Homo sapiens]
Length = 1403
Score = 753 bits (1945), Expect = 0.0
Identities = 390/922 (42%), Positives = 518/922 (56%), Gaps = 33/922 (3%)
Query: 497 VLSPVEPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCS 556
+LSP C G+ C + C+ GG+ C+ A C GDPHY +FDGR++D GTC+
Sbjct: 41 LLSP--DPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCN 98
Query: 557 YTMVE---LCSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLV 613
Y + L L F+V KNE+RG+ VSYV +VTV A ++S+ + E+G V V
Sbjct: 99 YVLATTGCLGVSTQGLTPFTVTTKNENRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRV 158
Query: 614 DNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCG 673
+ + LPVS+++GR+ V Q +A++ FGL V+YDW+ ++ ++LP+ + VCGLCG
Sbjct: 159 NGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCG 218
Query: 674 NYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDR 733
N + +P +D + P+G LAP + SW+ D LC D C+ +CP C + + YEG
Sbjct: 219 NMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPG 278
Query: 734 LCGMLTK-LDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGIS 792
CG L GPF CH + P F + CV D+C+ GG+ LC+ L++Y AC G+
Sbjct: 279 FCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVV 338
Query: 793 VGDWRSPANCPLSCPANSRYELCGPACPTSCNGAA---APSNCSGRPCVEGCVCLPGFVA 849
+ DWR+ C ++CP NS YE+CGP CP SC A P+ C G PCVEGC C GFV
Sbjct: 339 IEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEG-PCVEGCQCDAGFVL 397
Query: 850 SGGACVPASS-CGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERC 908
S CVP ++ CGC G G E WAD C + C C + C SC GE C
Sbjct: 398 SADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPA-SCGLGEVC 456
Query: 909 SV-QNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSC-GQNAALPAFRV 966
+ +G GC P CQ GDPHYV+ DG RFDF GTC YLL C G F V
Sbjct: 457 GLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTV 516
Query: 967 LVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQ 1026
V NEHRGSQ VSYTR+V ++ + + +P ++ VD V LPFQ D +
Sbjct: 517 TVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQL-DSLLHAHLS 575
Query: 1027 GRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANA 1086
G D VV T GL++ +D ++ V +VP++YA +LCGLCGN+N DPADDL GG A
Sbjct: 576 GADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAG-- 633
Query: 1087 LAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQ-LQSKNECGILADPKGPFRECHSKLDP 1145
WQ GCG CP + Q+ + CG+++ GP CH + P
Sbjct: 634 ------WQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPP 687
Query: 1146 QGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEA 1205
+ C+ D C + G G LC A+ATY AACQAAGA + WR + CPL CP HSHYE
Sbjct: 688 AQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYEL 747
Query: 1206 CSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTF 1265
C CP+SC L P GC S C EGCVCD GF LSG++C+P+ CGC+H G Y+P G+ F
Sbjct: 748 CGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVF 807
Query: 1266 YPGPGCDSLCHCQEGGLVSC-ESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTF 1324
YPGP C+ C C GG V+C E ++CGPHE C+ G C A G C A+G HY T
Sbjct: 808 YPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITL 867
Query: 1325 DGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLE 1384
DGR +D G+C YVLAQ C +PG F+++ E A G+ + + V VA + L
Sbjct: 868 DGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGD-----LQRLLVTVAGQVVSLA 922
Query: 1385 QRQWKVTVRADGEQGARGLWVG 1406
Q Q +VTV DGE A + VG
Sbjct: 923 QGQ-QVTV--DGEAVALPVAVG 941
Score = 585 bits (1507), Expect = e-166
Identities = 320/862 (37%), Positives = 433/862 (50%), Gaps = 37/862 (4%)
Query: 505 CEGMQCAAGQRCQVV-GGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELC 563
C C G+ C ++ G+ GC STA C+A GDPHY T DG R+D GTC Y + C
Sbjct: 445 CTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPC 504
Query: 564 SEDDT-LPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPV 622
F+V NEHRGS+ VSY VT++ Y+HS++L+ + VD LP
Sbjct: 505 HGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPF 564
Query: 623 SLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADD 682
L + L + SG VV GL + +D D + L +PA + +CGLCGNYN DPADD
Sbjct: 565 QL-DSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADD 623
Query: 683 FLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPA-CTPGQAQHYEGDRLCGMLTKL 741
G A W++ G C + CP+ CTP Q + + G CG+++
Sbjct: 624 LKAVGGKPA--------GWQVG-GAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISAT 674
Query: 742 DGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPAN 801
DGP A CH + P + + C+ D C V G LC ++ Y AC G +G+WR P
Sbjct: 675 DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDF 734
Query: 802 CPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCG 861
CPL CPA+S YELCG +CP SC +AP C C EGCVC GFV SG CVP CG
Sbjct: 735 CPLQCPAHSHYELCGDSCPVSCPSLSAPEGCESA-CREGCVCDAGFVLSGDTCVPVGQCG 793
Query: 862 CTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDR 921
C G G+ + C+RRC C H VTC++ +C E C +++G+ C+
Sbjct: 794 CLHDGRYYPLGEVFYPGPECERRCECGPGGH-VTCQEGAACGPHEECRLEDGVQACHATG 852
Query: 922 FGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYT 981
G C +G HY++ DGR +D G+C+Y+L C F +++E G
Sbjct: 853 CGRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGD-----L 907
Query: 982 RAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVT 1041
+ + V G V++ + QV VD LP A G+V+V +GR+ V++T GL +
Sbjct: 908 QRLLVTVAGQVVSLAQGQ--QVTVDGEAVALP--VAVGRVRVTAEGRNMVLQTTKGLRLL 963
Query: 1042 YDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEE-TRPG 1100
+D +A + +PS + LCGLCGNFNG+ +DD L G A++ FG +W+ + G
Sbjct: 964 FDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKG 1023
Query: 1101 CG-ATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLL 1159
CG P CP + +S CG L +P+GPF C + L P R CVYD C
Sbjct: 1024 CGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQ 1083
Query: 1160 PGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPV 1219
G LC +LA Y AACQAAG V PWR++ CPL CP HSHY C+ C SC L
Sbjct: 1084 KGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSG 1143
Query: 1220 PGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQE 1279
GC + C EGC CD+ F LS C+P+ CGC H G Y P + C C C
Sbjct: 1144 LTGCTTRCFEGCECDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTS-DCSERCSCSS 1202
Query: 1280 GGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVL 1339
++C+++ C P C+ + C A C S + TTFDG R VY L
Sbjct: 1203 SSGLTCQAAGCPPGRVCEVKAEARNCWAT-RGLCVLSVGANLTTFDGARGATTSPGVYEL 1261
Query: 1340 AQTCGTRPGLHRFAVLQENVAW 1361
+ C PG LQ + W
Sbjct: 1262 SSRC---PG------LQNTIPW 1274
Score = 323 bits (827), Expect = 1e-87
Identities = 195/581 (33%), Positives = 282/581 (48%), Gaps = 39/581 (6%)
Query: 506 EGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSE 565
EG C + C++ G C A C A G HY T DGR YD+ G+CSY + ++C
Sbjct: 829 EGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHP 888
Query: 566 DDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLS 625
FS+ + G + LVTV VSL +G+ V VD + LPV++
Sbjct: 889 KPGDEDFSIVLEKNAAGDLQRL---LVTVAG--QVVSLAQGQQ--VTVDGEAVALPVAV- 940
Query: 626 EGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLT 685
GR+RV G V++ GL + +D D L +S+P+ F+ ++CGLCGN+NG+ +DDF+
Sbjct: 941 -GRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVL 999
Query: 686 PDGALAPDAVEFASSWKLDDGDYLCEDGC-QNNCPACTPGQAQHYEGDRLCGMLTKLDGP 744
P+G+ A F ++W++ C +GC CP C + YE + CG L GP
Sbjct: 1000 PNGSAASSVETFGAAWRVPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGP 1059
Query: 745 FAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPL 804
FA C L P + QCVYDLC G++ LCR L+AY AC G++V WR+ + CPL
Sbjct: 1060 FATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPL 1119
Query: 805 SCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGCTF 864
CPA+S Y +C C SC + + C+ R C EGC C F+ S G C+P CGCT
Sbjct: 1120 HCPAHSHYSICTRTCQGSCAALSGLTGCTTR-CFEGCECDDRFLLSQGVCIPVQDCGCTH 1178
Query: 865 QGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGT 924
G L + + C RC+C+ ++ +TC+ CP G C V+ C+ R G
Sbjct: 1179 NGRYLPVNSSLLTSD-CSERCSCSSSSG-LTCQ-AAGCPPGRVCEVKAEARNCWATR-GL 1234
Query: 925 CQGSGDPHYVSFDGRRFDFMGTCTYLLVGSC-GQNAALPAFRVLVENE--HRGSQTVSYT 981
C S + +FDG R Y L C G +P +RV+ E + H ++ V
Sbjct: 1235 CVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVGQV 1294
Query: 982 RAVRVEA-------RGVKV-AVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVR 1033
+ +GV V +R + P + L + P DG + +VR
Sbjct: 1295 HIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTP----DGSL---------LVR 1341
Query: 1034 TDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADD 1074
G+ V N +V V + +A LCG CGNF+GD +D
Sbjct: 1342 QKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTND 1382
Score = 42.7 bits (99), Expect = 0.003
Identities = 49/190 (25%), Positives = 82/190 (43%), Gaps = 23/190 (12%)
Query: 504 SCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELC 563
+C+ C G+ C+V C A + +C + TTFDG R Y + C
Sbjct: 1207 TCQAAGCPPGRVCEVKAEARNCWA-TRGLCVLSVGANLTTFDGARGATTSPGVYELSSRC 1265
Query: 564 SE-DDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLP- 621
+T+P + V A+ + + + VG V + V+LT + V V+ R LP
Sbjct: 1266 PGLQNTIPWYRVVAEVQICHGKTEA-VGQVHIFFQDGMVTLTPNKG--VWVNGLRVDLPA 1322
Query: 622 -----VSLS---EGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCG 673
VS+S +G L V Q G+ V + ++A+ + ++CG CG
Sbjct: 1323 EKLASVSVSRTPDGSLLVRQKA---------GVQVWLGANGKVAVIVSNDHAGKLCGACG 1373
Query: 674 NYNGDPADDF 683
N++GD +D+
Sbjct: 1374 NFDGDQTNDW 1383
>gi|134268640 tectorin alpha precursor [Homo sapiens]
Length = 2155
Score = 560 bits (1444), Expect = e-159
Identities = 312/906 (34%), Positives = 455/906 (50%), Gaps = 25/906 (2%)
Query: 505 CEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCS 564
C+ C+ + C+ G C A T+ C G+PHY TFDG + G+C+Y + C
Sbjct: 294 CQEASCSPYEVCEPKGKFFYCSAVETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCL 353
Query: 565 EDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSL 624
+ +LP FSVEAKNEHR VS+V ++V + + + +G G V V++ + LPV+L
Sbjct: 354 QTSSLPFFSVEAKNEHRRGSAVSWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTL 413
Query: 625 SEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFL 684
G +++YQSG VE FGL+VT+D ++S+P + + CGLCGNYN +P DDFL
Sbjct: 414 DLGTVKIYQSGISTAVETDFGLLVTFDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFL 473
Query: 685 TPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGP 744
PDG A ++ SW++ D+ C+ GC +NC C Y G CG L K DGP
Sbjct: 474 RPDGRPAMSVLDLGESWRVYHADWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGP 533
Query: 745 FAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANC-- 802
C +DP F+ CVYDLC V LC+ + AYA C LGI +GDWR+ C
Sbjct: 534 LWECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVS 593
Query: 803 PLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGC 862
+ CP+ S Y +C +CP +C+ A NC+ PC EGC C GFV S CVP CGC
Sbjct: 594 TVQCPSFSHYSVCTSSCPDTCSDLTASRNCA-TPCTEGCECNQGFVLSTSQCVPLHKCGC 652
Query: 863 TFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRF 922
F G G+ WA C +C C V C +K +C +GE C+V++G GC+P R
Sbjct: 653 DFDGHYYTMGEFFWATANCTVQCLCEEG-GDVYCFNK-TCGSGEVCAVEDGYQGCFPKRE 710
Query: 923 GTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTR 982
C S + +FDG + F +Y L+ +C + P + + N+ + ++ R
Sbjct: 711 TVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPER---PEYLEIDINKKKPDAGPAWLR 767
Query: 983 AVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTY 1042
+R+ +V + +V ++ LPF G+++++R V + +TV Y
Sbjct: 768 GLRILVADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVESKGVVTVQY 827
Query: 1043 DWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQ--EETRPG 1100
+ ++ ++Y GLCG +N + +D+ L G N F SW EE G
Sbjct: 828 SDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTFEEICNG 887
Query: 1101 CGATEPGDCPKL---DSLVAQQLQSKNECGILADP-KGPFRECHSKLDPQGAVRDCVYDR 1156
E GD K DS + + +S++ CGI+ DP F ECH ++ R C++
Sbjct: 888 ----ECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRL 943
Query: 1157 CLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGD 1216
C G LCD++A YA+AC+ A V PWR+ + CPL CP +SH+E C C +C
Sbjct: 944 CQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEEC-ITCTETCET 1002
Query: 1217 LPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCH 1276
L + C C EGC CDEG+AL G C+ + CGC +G +TF+ C C+
Sbjct: 1003 LTLGPICVDSCSEGCQCDEGYALLGSQCVTRSECGCNFEGHQLATNETFWVDLDCQIFCY 1062
Query: 1277 CQ-EGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTC 1335
C V CE+ C E C GG C A ++C SG HY TFDG FDF +C
Sbjct: 1063 CSGTDNRVHCETIPCKDDEYCMEEGGLYYCQARTDASCIVSGYGHYLTFDGFPFDFQTSC 1122
Query: 1336 VYVLAQTCGTRP---GLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTV 1392
+L T G+RP +F V +N + + V V +++ + R +K TV
Sbjct: 1123 PLILC-TTGSRPSSDSFPKFVVTAKNEDRDPSLALWVKQVDVTVFGYSIVI-HRAYKHTV 1180
Query: 1393 RADGEQ 1398
+ E+
Sbjct: 1181 LVNSER 1186
Score = 474 bits (1220), Expect = e-133
Identities = 278/903 (30%), Positives = 408/903 (45%), Gaps = 28/903 (3%)
Query: 505 CEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCS 564
C C +G+ C V G GC + VC + TFDG Y SYT+++ C
Sbjct: 685 CFNKTCGSGEVCAVEDGYQGCFPKRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCP 744
Query: 565 EDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSL 624
E + K G +++ + + V + V ++ Q LP
Sbjct: 745 ERPEYLEIDINKKKPDAGP---AWLRGLRILVADQEVKIGGIGASEVKLNGQEVELPFFH 801
Query: 625 SEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFL 684
G+L +Y++ VE + V Y L + L + + GLCG YN + +D+F
Sbjct: 802 PSGKLEIYRNKNSTTVESKGVVTVQYSDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFC 861
Query: 685 TPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQA--QHYEGDRLCGMLTK-L 741
P+G + F SW + +C C + AC + Y CG++
Sbjct: 862 LPNGKCTDNLAVFLESWTTFEE--ICNGECGDLLKACNNDSELLKFYRSRSRCGIINDPS 919
Query: 742 DGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPAN 801
+ F CH ++ + C++ LC GG LC ++ YA AC + VG WR+
Sbjct: 920 NSSFLECHGVVNVTAYYRTCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDF 979
Query: 802 CPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCG 861
CPL CP NS +E C C +C C C EGC C G+ G CV S CG
Sbjct: 980 CPLECPENSHFEEC-ITCTETCETLTLGPICVDS-CSEGCQCDEGYALLGSQCVTRSECG 1037
Query: 862 CTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDR 921
C F+G QLA + W D CQ C C+G ++V C + C E C + GL C
Sbjct: 1038 CNFEGHQLATNETFWVDLDCQIFCYCSGTDNRVHC-ETIPCKDDEYCMEEGGLYYCQART 1096
Query: 922 FGTCQGSGDPHYVSFDGRRFDFMGTCTYLL--VGSCGQNAALPAFRVLVENEHRGSQTVS 979
+C SG HY++FDG FDF +C +L GS + + P F V +NE R
Sbjct: 1097 DASCIVSGYGHYLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNEDRDPSLAL 1156
Query: 980 YTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLT 1039
+ + V V G + + R Y VLV+ YLP + G++ +F G VV TDFGL
Sbjct: 1157 WVKQVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLK 1216
Query: 1040 VTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEET-- 1097
V YDW ++ VP S + GLCG +NG+P DDL + G A++ FG SW +
Sbjct: 1217 VVYDWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKRDTF 1276
Query: 1098 -RPGCGATEPGDCPKLDSLV-AQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYD 1155
+ GCG P C K++ QQL C ++ + F +CHSK++P ++C++D
Sbjct: 1277 CQVGCGDRCPS-CAKVEGFSKVQQL-----CSLIPNQNAAFSKCHSKVNPTFFYKNCLFD 1330
Query: 1156 RCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCG 1215
C+ G C L YA+ CQ G TV WR+ C ++CPP+SHYE+C C C
Sbjct: 1331 SCIDGGAVQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCA 1390
Query: 1216 DLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLC 1275
+ + C C EGC CD G+ L+G+SC+ SCGC G Y+ P Q F+ C C
Sbjct: 1391 AIRLKSDCSHYCVEGCHCDAGYVLNGKSCILPHSCGCYSDGKYYEPKQLFW-NSDCTRRC 1449
Query: 1276 HCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTC 1335
C ++ C+ C E C G GC + +S C A+G + TFDG F C
Sbjct: 1450 RCFRRNVIQCDPRQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANC 1509
Query: 1336 VYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVRAD 1395
+VL+ C P + F ++ W +++ + + + + R TV+ +
Sbjct: 1510 AFVLSTICQKLPDI-SFQLIINFDKWSAPNLTIISPVYFYINEEQILINDRN---TVKVN 1565
Query: 1396 GEQ 1398
G Q
Sbjct: 1566 GTQ 1568
Score = 355 bits (911), Expect = 2e-97
Identities = 211/698 (30%), Positives = 322/698 (46%), Gaps = 21/698 (3%)
Query: 505 CEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCS 564
CE + C + C GG C A + A C G HY TFDG +D +C + S
Sbjct: 1072 CETIPCKDDEYCMEEGGLYYCQARTDASCIVSGYGHYLTFDGFPFDFQTSCPLILCTTGS 1131
Query: 565 E--DDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPV 622
D+ P F V AKNE R +V V V + +S+ + R VLV+++R LP+
Sbjct: 1132 RPSSDSFPKFVVTAKNEDRDPSLALWVKQVDVTVFGYSIVIHRAYKHTVLVNSERLYLPL 1191
Query: 623 SLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADD 682
L +G++ ++ G VVE FGL V YDW L++++P Q+ GLCG YNG+P DD
Sbjct: 1192 KLGQGKINIFSFGFHVVVETDFGLKVVYDWKTFLSITVPRSMQNSTYGLCGRYNGNPDDD 1251
Query: 683 FLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLD 742
P G LA EF SW D C+ GC + CP+C + + +LC ++ +
Sbjct: 1252 LEMPMGLLASSVNEFGQSWV--KRDTFCQVGCGDRCPSCAKVEG-FSKVQQLCSLIPNQN 1308
Query: 743 GPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANC 802
F+ CH ++P F + C++D C+ GG + C L YA C GI+V WR+ +C
Sbjct: 1309 AAFSKCHSKVNPTFFYKNCLFDSCIDGGAVQTACSWLQNYASTCQTQGITVTGWRNYTSC 1368
Query: 803 PLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGC 862
++CP NS YE C C C S+CS CVEGC C G+V +G +C+ SCGC
Sbjct: 1369 TVTCPPNSHYESCVSVCQPRCAAIRLKSDCS-HYCVEGCHCDAGYVLNGKSCILPHSCGC 1427
Query: 863 TFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRF 922
G P Q W + C RRC C + + C D + C + E C+++NG+ GC+ +
Sbjct: 1428 YSDGKYYEPKQLFWNSD-CTRRCRCF-RRNVIQC-DPRQCKSDEECALRNGVRGCFSTKT 1484
Query: 923 GTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTR 982
C +G + +FDG F C ++L C Q +F++++ + + ++
Sbjct: 1485 SYCLAAGGGVFRTFDGAFLRFPANCAFVLSTIC-QKLPDISFQLIINFDKWSAPNLTIIS 1543
Query: 983 AVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTY 1042
V ++ + V V+ +PF +++ V+ T + + Y
Sbjct: 1544 PVYFYINEEQILINDR--NTVKVNGTQVNVPFITGLA-TKIYSSEGFLVIDTSPDIQIYY 1600
Query: 1043 DWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSW------QEE 1096
+ + + +CGLCGNFNGD DD G +++ SW +
Sbjct: 1601 NGFNVIKISISERLQNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKTNGMQKRP 1660
Query: 1097 TRPGCGATEPGDCPKL-DSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYD 1155
P C + + D++ Q++Q C L D KG F+ C+ LDP C D
Sbjct: 1661 LAPSCNELQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYLD 1720
Query: 1156 RCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELC 1193
C + LC +LA Y AC++ G W +E C
Sbjct: 1721 GC-YSHKKFQLCGSLAAYGEACRSFGILSTEWIEKENC 1757
Score = 342 bits (878), Expect = 1e-93
Identities = 183/512 (35%), Positives = 250/512 (48%), Gaps = 9/512 (1%)
Query: 842 VCLPG---FVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRD 898
V +PG F G PA+ GCT +G L G+ W D C +C C +++ C++
Sbjct: 239 VNVPGRWAFKVDGKEIDPAN--GCTSRGQFLRRGEVFWDDLNCTVKCRCLDFNNEIYCQE 296
Query: 899 KQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQN 958
SC E C + C TC G+PHY +FDG F F G+C YLL C Q
Sbjct: 297 -ASCSPYEVCEPKGKFFYCSAVETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQT 355
Query: 959 AALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAAD 1018
++LP F V +NEHR VS+ + + VE G K+ + + G+V V+D++ LP
Sbjct: 356 SSLPFFSVEAKNEHRRGSAVSWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDL 415
Query: 1019 GQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALR 1078
G V++++ G V TDFGL VT+D + VP SY + CGLCGN+N +P DD
Sbjct: 416 GTVKIYQSGISTAVETDFGLLVTFDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRP 475
Query: 1079 GGGQAANALAFGNSWQ-EETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFR 1137
G A + L G SW+ C + +C + D+ + CG L GP
Sbjct: 476 DGRPAMSVLDLGESWRVYHADWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGPLW 535
Query: 1138 ECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELC--PL 1195
EC + +DP V CVYD C + LC A+ YA CQA G + WR++ C +
Sbjct: 536 ECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTV 595
Query: 1196 SCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQ 1255
CP SHY C+ CP +C DL C + C EGC C++GF LS C+PL CGC
Sbjct: 596 QCPSFSHYSVCTSSCPDTCSDLTASRNCATPCTEGCECNQGFVLSTSQCVPLHKCGCDFD 655
Query: 1256 GTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQA 1315
G Y+ G+ F+ C C C+EGG V C + +CG E C G GC + C
Sbjct: 656 GHYYTMGEFFWATANCTVQCLCEEGGDVYCFNKTCGSGEVCAVEDGYQGCFPKRETVCLL 715
Query: 1316 SGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRP 1347
S + TFDG + F Y L +TC RP
Sbjct: 716 SQNQVLHTFDGASYAFPSEFSYTLLKTCPERP 747
Score = 129 bits (324), Expect = 2e-29
Identities = 91/340 (26%), Positives = 142/340 (41%), Gaps = 41/340 (12%)
Query: 505 CEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCS 564
C+ QC + + C + G GC + T+ C A G + TFDG C++ + +C
Sbjct: 1459 CDPRQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANCAFVLSTICQ 1518
Query: 565 EDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSL 624
+ LP S + + + V Y + + + V V+ + +P +
Sbjct: 1519 K---LPDISFQLIINFDKWSAPNLTIISPVYFYINEEQILINDRNTVKVNGTQVNVPF-I 1574
Query: 625 SEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFL 684
+ ++Y S V++ + + Y+ + +S+ R Q++VCGLCGN+NGD DD++
Sbjct: 1575 TGLATKIYSSEGFLVIDTSPDIQIYYNGFNVIKISISERLQNKVCGLCGNFNGDLTDDYV 1634
Query: 685 TPDGALAPDAVEFASSWKLDDGDYLCEDGCQNN--CPACTPGQAQHY------------E 730
T G +V A SWK +G Q P+C Q Y +
Sbjct: 1635 TLRGKPVVSSVVLAQSWK--------TNGMQKRPLAPSCNELQFSQYAAMCDNVHIQKMQ 1686
Query: 731 GDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELG 790
GD C LT + G F C+ LDP PF E C D C ++ LC L+AY +AC G
Sbjct: 1687 GDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYLDGC-YSHKKFQLCGSLAAYGEACRSFG 1745
Query: 791 ISVGDWRSPANCP--------------LSCPANSRYELCG 816
I +W NC +C + ELCG
Sbjct: 1746 ILSTEWIEKENCSGVVEDPCVGADCPNRTCELGNGRELCG 1785
Score = 94.4 bits (233), Expect = 7e-19
Identities = 46/132 (34%), Positives = 69/132 (52%), Gaps = 1/132 (0%)
Query: 1251 GCVHQGTYHPPGQTFYPGPGCDSLCHCQE-GGLVSCESSSCGPHEACQPSGGSLGCVAVG 1309
GC +G + G+ F+ C C C + + C+ +SC P+E C+P G C AV
Sbjct: 259 GCTSRGQFLRRGEVFWDDLNCTVKCRCLDFNNEIYCQEASCSPYEVCEPKGKFFYCSAVE 318
Query: 1310 SSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVT 1369
+STC G+PHY TFDG F F G+C Y+LA+ C L F+V +N VS
Sbjct: 319 TSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHRRGSAVSWV 378
Query: 1370 RVITVQVANFTL 1381
+ ++V+V + +
Sbjct: 379 KELSVEVNGYKI 390
>gi|16554449 zonadhesin isoform 3 [Homo sapiens]
Length = 2812
Score = 555 bits (1429), Expect = e-157
Identities = 313/860 (36%), Positives = 433/860 (50%), Gaps = 24/860 (2%)
Query: 505 CEGMQCAAGQRCQVVGGKAGCVAES-TAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELC 563
C+ QC CQ+ G+ GC + TA C GDPHY TFDGR + MG C+Y + + C
Sbjct: 1127 CQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPC 1186
Query: 564 SEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVS 623
+ T P F V AKNE +G VS + V V +V+L +G LV Q+ LP
Sbjct: 1187 G-NSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGRR--TLVGGQQVTLPAI 1243
Query: 624 LSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDF 683
S+G + + SG ++ FGL V +D D QL +++ + + ++CGLCGNY+G+ +D
Sbjct: 1244 PSKG-VFLGASGRFVELQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDH 1302
Query: 684 LTPDGALAPDAVEFASSWKLD-DGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLD 742
L DG+ A D E +SW+ D D D C+ N P+C G CG L
Sbjct: 1303 LKLDGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTH 1362
Query: 743 GPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANC 802
GPF C + F + C+ D+C G + LC +S C + G +V WR P C
Sbjct: 1363 GPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFC 1422
Query: 803 PLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGC 862
P++CP NS+Y LC CP +C+ + CS R CVE C C PGFV SG C+P S CGC
Sbjct: 1423 PMACPPNSKYSLCAKPCPDTCHSGFSGMFCSDR-CVEACECNPGFVLSGLECIPRSQCGC 1481
Query: 863 TFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRF 922
E W C+ C C + +++ C+ + C A E C Q+G+ GC+
Sbjct: 1482 LHPAGSYFKVGERWYKPGCKELCVCE-SNNRIRCQPWR-CRAQEFCGQQDGIYGCHAQGA 1539
Query: 923 GTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGS-QTVSYT 981
TC SGDPHY++FDG FMGTCTY+L C + F V NE+RG VSY
Sbjct: 1540 ATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYI 1599
Query: 982 RAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVT 1041
+AV V + +++ R +V+++ LP A G+V + ++ T+FGL V
Sbjct: 1600 KAVHVTVFDLSISLLRGC--KVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVR 1657
Query: 1042 YDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQ--EETRP 1099
YD + V VPSSY LCGLCGN+N + DD A +++ G +W+ E + P
Sbjct: 1658 YDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEP 1717
Query: 1100 GCGAT--EPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRC 1157
GC +P C + A +KN C IL +P+GPF +CH + PQ + CV+ +C
Sbjct: 1718 GCFLVGGKPSSCQENSMADA---WNKN-CAILINPQGPFSQCHQVVPPQSSFASCVHGQC 1773
Query: 1158 LLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDL 1217
G + LC +L YA+ C AG WR+ CP+ CPP S Y CS CP +C +
Sbjct: 1774 GTKGDTTALCRSLQAYASLCAQAG-QAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSI 1832
Query: 1218 PVPGGC--GSECHEGCVCDEGFALSGESCLPLASCGCVH-QGTYHPPGQTFYPGPGCDSL 1274
P C C E C C +G LSG SC+PL CGC G+YHP G+ +Y C L
Sbjct: 1833 NNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRL 1892
Query: 1275 CHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGT 1334
C C ++C S+C P++ C G L C A G CQ G+ HY +FDG
Sbjct: 1893 CTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDA 1952
Query: 1335 CVYVLAQTCGTRPGLHRFAV 1354
C VL + C L F +
Sbjct: 1953 CTLVLVKVCHPAMALPFFKI 1972
Score = 475 bits (1223), Expect = e-133
Identities = 287/869 (33%), Positives = 416/869 (47%), Gaps = 43/869 (4%)
Query: 505 CEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCS 564
C+ +C A + C G GC A+ A C A GDPHY TFDG + MGTC+Y + C
Sbjct: 1514 CQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCW 1573
Query: 565 EDDTLPAFSVEAKNEHRGS-RRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVS 623
F V A NE+RG VSY+ V V + S+SL RG V+++ R LPV
Sbjct: 1574 SRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCK--VMLNGHRVALPVW 1631
Query: 624 LSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDF 683
L++GR+ + S ++ FGL V YD + +++P+ + Q+CGLCGNYN + DD
Sbjct: 1632 LAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDN 1691
Query: 684 LTPDGALAPDAVEFASSWKLDDGDYLCEDGC--QNNCPACTPGQAQHYEGDRLCGMLTKL 741
L PD LA D+++ ++WKL + E GC P+ + ++ C +L
Sbjct: 1692 LRPDRKLAGDSMQLGAAWKLPESS---EPGCFLVGGKPSSCQENSMADAWNKNCAILINP 1748
Query: 742 DGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPAN 801
GPF+ CH + P+ CV+ C G+ +LCR L AYA C + G + WR+
Sbjct: 1749 QGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQAPA-WRNRTF 1807
Query: 802 CPLSCPANSRYELCGPACPTSCNGAAAPSNC-SGRPCVEGCVCLPGFVASGGACVPASSC 860
CP+ CP S Y C CP +C+ P +C PC E C C G + SG +CVP C
Sbjct: 1808 CPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQC 1867
Query: 861 GCTFQGLQLAPGQEVWADE-LCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYP 919
GCT P E W E C R CTC+ + +TC + +C + C +GLL C
Sbjct: 1868 GCTDPAGSYHPVGERWYTENTCTRLCTCS-VHNNITCF-QSTCKPNQICWALDGLLRCRA 1925
Query: 920 DRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVS 979
G CQ G+ HYVSFDG CT +LV C ALP F++ ++E T +
Sbjct: 1926 SGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEA 1985
Query: 980 YT-RAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGL 1038
+ V ++ +V +++ + +VL++ LP + V V ++V G+
Sbjct: 1986 FRLHEVYIDIYDAQVTLQKGH--RVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGV 2043
Query: 1039 TVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQE-ET 1097
V +D N + ++P++Y +CG+CGNFN + D+L + A + F NSW++ +
Sbjct: 2044 QVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDI 2103
Query: 1098 RPGCGA---------TEPGDCPKLDSLVAQQLQSKNECGILADPKGP-FRECHSKLDPQG 1147
P C + E + P + A +++ +C A + P + +C S++D
Sbjct: 2104 DPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCE--AALRAPVWAQCASRIDLTP 2161
Query: 1148 AVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACS 1207
+ DC C G LC AL + A CQ+ G WR+ CPL CP +S Y C
Sbjct: 2162 FLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCL 2221
Query: 1208 YGCPLSCGDLPVPGGC-----GSECHEGCVCDEGFALSGESCLPLASCGC--VHQGTYHP 1260
C SC DL G C S C EGC+C G+ LS + C+P + CGC H G+ P
Sbjct: 2222 PSCSPSCWDL--DGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSI-P 2278
Query: 1261 PGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQ--PSGGSLGCVAVGSSTCQASGD 1318
G++ + GC C C GG + C C CQ + CV+ S C GD
Sbjct: 2279 LGKS-WVSSGCTEKCVC-TGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGD 2336
Query: 1319 PHYTTFDGRRFDFMGTCVYVLAQTCGTRP 1347
P Y TFDG + G YVL +T P
Sbjct: 2337 PRYLTFDGFSYRLQGRMTYVLIKTVDVLP 2365
Score = 384 bits (986), Expect = e-106
Identities = 228/631 (36%), Positives = 309/631 (48%), Gaps = 19/631 (3%)
Query: 779 LSAYAQACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCV 838
+S +A + + +G + + CP N+RYE C ACP SC +P G C
Sbjct: 1017 MSPHAPSTPMTSVILGTTTTSRSSTERCPPNARYESC--ACPASCK---SPRPSCGPLCR 1071
Query: 839 EGCVCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRD 898
EGCVC PGF+ S C+ ASSC C + PG E W C C C + +V C+
Sbjct: 1072 EGCVCNPGFLFSDNHCIQASSCNCFYNNDYYEPGAE-WFSPNCTEHCRCWPGS-RVECQI 1129
Query: 899 KQSCPAGERCSVQNGLLGCYPDR-FGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQ 957
Q C C ++NG GC+P TC GDPHYV+FDGR F FMG CTY+L CG
Sbjct: 1130 SQ-CGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCG- 1187
Query: 958 NAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAA 1017
N+ P FRV +NE +G + VS V V V + + + LV LP +
Sbjct: 1188 NSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGR--RTLVGGQQVTLPAIPS 1245
Query: 1018 DGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLAL 1077
G V + GR ++T+FGL V +D + ++ V S+Y+ LCGLCGN++G+ +D
Sbjct: 1246 KG-VFLGASGRFVELQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLK 1304
Query: 1078 RGGGQAANALAFGNSWQ--EETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGP 1135
G A + GNSWQ ++ C + + P DS + + CG L D GP
Sbjct: 1305 LDGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGP 1364
Query: 1136 FRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPL 1195
F C + C+ D C G LC ++T CQ AG V PWR CP+
Sbjct: 1365 FETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPM 1424
Query: 1196 SCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQ 1255
+CPP+S Y C+ CP +C C C E C C+ GF LSG C+P + CGC+H
Sbjct: 1425 ACPPNSKYSLCAKPCPDTCHSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHP 1484
Query: 1256 -GTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQ 1314
G+Y G+ +Y PGC LC C+ + C+ C E C G GC A G++TC
Sbjct: 1485 AGSYFKVGERWYK-PGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCT 1543
Query: 1315 ASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITV 1374
ASGDPHY TFDG FMGTC YVL + C +R F V N G G + V+ + V
Sbjct: 1544 ASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRG-GILEVSYIKAV 1602
Query: 1375 QVANFTLRLEQRQWKVTVRADGEQGARGLWV 1405
V F L + + V +G + A +W+
Sbjct: 1603 HVTVFDLSISLLR-GCKVMLNGHRVALPVWL 1632
Score = 323 bits (829), Expect = 6e-88
Identities = 235/847 (27%), Positives = 357/847 (42%), Gaps = 87/847 (10%)
Query: 504 SCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELC 563
+C C Q C + G C A VC+ G+ HY +FDG + + C+ +V++C
Sbjct: 1902 TCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVC 1961
Query: 564 SEDDTLPAFSVEAKNE-HRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPV 622
LP F + AK+E G + V + Y V+L +G VL+++++ LP
Sbjct: 1962 HPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQKGHR--VLINSKQVTLPA 2019
Query: 623 SLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADD 682
+ V S ++V + G+ V +D + L + +P + +VCG+CGN+N + D+
Sbjct: 2020 ISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDE 2079
Query: 683 FLTPDGALAPDAVEFASSWKLDDGDYLCEDGC--QNNCPACTPGQAQHYEGDRLCGMLTK 740
+ P +A EF +SWK D D C+ + PA Q ++ G+ L +
Sbjct: 2080 LMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPA---EQQENPSGNCRAADLRR 2136
Query: 741 --------LDGP-FAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGI 791
L P +A C +D PFL C LC GG +LC+ L A+ C G+
Sbjct: 2137 AREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGL 2196
Query: 792 SVGDWRSPANCPLSCPANSRYELCGPACPTS-------CNGAAAPSNCSGRPCVEGCVCL 844
WR+ + CPL CPA S Y C P+C S C GA PS C EGC+C
Sbjct: 2197 KPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPS-----ACAEGCICQ 2251
Query: 845 PGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPA 904
PG+V S CVP S CGC P + W C +C C G + C D + CP+
Sbjct: 2252 PGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGA--IQCGDFR-CPS 2308
Query: 905 GERCSV--QNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALP 962
G C + N C D+ C GDP Y++FDG + G TY+L+ + LP
Sbjct: 2309 GSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVD---VLP 2365
Query: 963 --AFRVLVENEHRGSQTVS--YTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAAD 1018
+LVE ++ S + + V G KV ++ +++V++ +P++ +
Sbjct: 2366 EGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGL--ELVVNNQKMAVPYRPNE 2423
Query: 1019 GQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALR 1078
++V G+ + TDF L V++ +PS Y + GLCGN++ + +D+ L
Sbjct: 2424 -HLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLP 2482
Query: 1079 GGGQAANALAFGNSWQEETRP-------GCGATEPGDCPKLDSLVAQQL----------Q 1121
G N FGNSW+ +T A E G +L Q+
Sbjct: 2483 SGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASN 2542
Query: 1122 SKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLL--PGQSGPL-CDALATYAAACQ 1178
S C +LADP+GPF CH + P+ CV D C P + L C L+ + + +
Sbjct: 2543 STQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGHGVSSR 2602
Query: 1179 AAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFA 1238
+ ++ + L + C P P G
Sbjct: 2603 YHISELY----DTLPSILCQPGR------------------PRGLRGPLRGRLRQHPRLC 2640
Query: 1239 LSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQP 1298
L PLA CGC G Y+ G +F C C C ++ CE SC E C
Sbjct: 2641 LQWHPEPPLADCGCTSNGIYYQLGSSFLT-EDCSQRCTCASSRILLCEPFSCRAGEVCTL 2699
Query: 1299 SGGSLGC 1305
+ GC
Sbjct: 2700 GNHTQGC 2706
Score = 160 bits (404), Expect = 1e-38
Identities = 131/454 (28%), Positives = 191/454 (42%), Gaps = 62/454 (13%)
Query: 505 CEGMQCAAGQRCQVVG--GKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVEL 562
C +C +G CQ+ + CV++ + C GDP Y TFDG Y + G +Y +++
Sbjct: 2301 CGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKT 2360
Query: 563 CSEDDTLPA----FSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRS 618
D LP VE +N+ R ++ V Y + V L G ++V+NQ+
Sbjct: 2361 V---DVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLE--LVVNNQKM 2415
Query: 619 RLPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGD 678
+P +E LRV G R + F LVV++ +SLP+ ++ V GLCGNY+ +
Sbjct: 2416 AVPYRPNE-HLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKN 2474
Query: 679 PADDFLTPDGALAPDAVEFASSWKLDDGDYL---------------CEDGCQNNCPA--C 721
+D + P GAL + F +SW++ D L E G + C
Sbjct: 2475 RKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSEC 2534
Query: 722 TPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLS---LCRG 778
+P Q + C +L GPFA CH T+ P PF E CV DLC R C+
Sbjct: 2535 SPEQLAS-NSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQV 2593
Query: 779 LSAYAQACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCV 838
LS + G+S S L LC P P G GR
Sbjct: 2594 LSGH-------GVSSRYHISELYDTLPSI------LCQPGRPRGLRGPLR-----GRLRQ 2635
Query: 839 EGCVCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRD 898
+CL P + CGCT G+ G ++ C +RCTC A+ ++ +
Sbjct: 2636 HPRLCLQWHPEP-----PLADCGCTSNGIYYQLGSSFLTED-CSQRCTC--ASSRILLCE 2687
Query: 899 KQSCPAGERCSVQNGLLGCYPDR---FGTCQGSG 929
SC AGE C++ N GC+P+ CQ G
Sbjct: 2688 PFSCRAGEVCTLGNHTQGCFPESPCLQNPCQNDG 2721
>gi|27881494 zonadhesin isoform 6 [Homo sapiens]
Length = 2721
Score = 555 bits (1429), Expect = e-157
Identities = 313/860 (36%), Positives = 433/860 (50%), Gaps = 24/860 (2%)
Query: 505 CEGMQCAAGQRCQVVGGKAGCVAES-TAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELC 563
C+ QC CQ+ G+ GC + TA C GDPHY TFDGR + MG C+Y + + C
Sbjct: 1127 CQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPC 1186
Query: 564 SEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVS 623
+ T P F V AKNE +G VS + V V +V+L +G LV Q+ LP
Sbjct: 1187 G-NSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGRR--TLVGGQQVTLPAI 1243
Query: 624 LSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDF 683
S+G + + SG ++ FGL V +D D QL +++ + + ++CGLCGNY+G+ +D
Sbjct: 1244 PSKG-VFLGASGRFVELQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDH 1302
Query: 684 LTPDGALAPDAVEFASSWKLD-DGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLD 742
L DG+ A D E +SW+ D D D C+ N P+C G CG L
Sbjct: 1303 LKLDGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTH 1362
Query: 743 GPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANC 802
GPF C + F + C+ D+C G + LC +S C + G +V WR P C
Sbjct: 1363 GPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFC 1422
Query: 803 PLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGC 862
P++CP NS+Y LC CP +C+ + CS R CVE C C PGFV SG C+P S CGC
Sbjct: 1423 PMACPPNSKYSLCAKPCPDTCHSGFSGMFCSDR-CVEACECNPGFVLSGLECIPRSQCGC 1481
Query: 863 TFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRF 922
E W C+ C C + +++ C+ + C A E C Q+G+ GC+
Sbjct: 1482 LHPAGSYFKVGERWYKPGCKELCVCE-SNNRIRCQPWR-CRAQEFCGQQDGIYGCHAQGA 1539
Query: 923 GTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGS-QTVSYT 981
TC SGDPHY++FDG FMGTCTY+L C + F V NE+RG VSY
Sbjct: 1540 ATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYI 1599
Query: 982 RAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVT 1041
+AV V + +++ R +V+++ LP A G+V + ++ T+FGL V
Sbjct: 1600 KAVHVTVFDLSISLLRGC--KVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVR 1657
Query: 1042 YDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQ--EETRP 1099
YD + V VPSSY LCGLCGN+N + DD A +++ G +W+ E + P
Sbjct: 1658 YDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEP 1717
Query: 1100 GCGAT--EPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRC 1157
GC +P C + A +KN C IL +P+GPF +CH + PQ + CV+ +C
Sbjct: 1718 GCFLVGGKPSSCQENSMADA---WNKN-CAILINPQGPFSQCHQVVPPQSSFASCVHGQC 1773
Query: 1158 LLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDL 1217
G + LC +L YA+ C AG WR+ CP+ CPP S Y CS CP +C +
Sbjct: 1774 GTKGDTTALCRSLQAYASLCAQAG-QAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSI 1832
Query: 1218 PVPGGC--GSECHEGCVCDEGFALSGESCLPLASCGCVH-QGTYHPPGQTFYPGPGCDSL 1274
P C C E C C +G LSG SC+PL CGC G+YHP G+ +Y C L
Sbjct: 1833 NNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRL 1892
Query: 1275 CHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGT 1334
C C ++C S+C P++ C G L C A G CQ G+ HY +FDG
Sbjct: 1893 CTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDA 1952
Query: 1335 CVYVLAQTCGTRPGLHRFAV 1354
C VL + C L F +
Sbjct: 1953 CTLVLVKVCHPAMALPFFKI 1972
Score = 475 bits (1223), Expect = e-133
Identities = 287/869 (33%), Positives = 416/869 (47%), Gaps = 43/869 (4%)
Query: 505 CEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCS 564
C+ +C A + C G GC A+ A C A GDPHY TFDG + MGTC+Y + C
Sbjct: 1514 CQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCW 1573
Query: 565 EDDTLPAFSVEAKNEHRGS-RRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVS 623
F V A NE+RG VSY+ V V + S+SL RG V+++ R LPV
Sbjct: 1574 SRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCK--VMLNGHRVALPVW 1631
Query: 624 LSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDF 683
L++GR+ + S ++ FGL V YD + +++P+ + Q+CGLCGNYN + DD
Sbjct: 1632 LAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDN 1691
Query: 684 LTPDGALAPDAVEFASSWKLDDGDYLCEDGC--QNNCPACTPGQAQHYEGDRLCGMLTKL 741
L PD LA D+++ ++WKL + E GC P+ + ++ C +L
Sbjct: 1692 LRPDRKLAGDSMQLGAAWKLPESS---EPGCFLVGGKPSSCQENSMADAWNKNCAILINP 1748
Query: 742 DGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPAN 801
GPF+ CH + P+ CV+ C G+ +LCR L AYA C + G + WR+
Sbjct: 1749 QGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQAPA-WRNRTF 1807
Query: 802 CPLSCPANSRYELCGPACPTSCNGAAAPSNC-SGRPCVEGCVCLPGFVASGGACVPASSC 860
CP+ CP S Y C CP +C+ P +C PC E C C G + SG +CVP C
Sbjct: 1808 CPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQC 1867
Query: 861 GCTFQGLQLAPGQEVWADE-LCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYP 919
GCT P E W E C R CTC+ + +TC + +C + C +GLL C
Sbjct: 1868 GCTDPAGSYHPVGERWYTENTCTRLCTCS-VHNNITCF-QSTCKPNQICWALDGLLRCRA 1925
Query: 920 DRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVS 979
G CQ G+ HYVSFDG CT +LV C ALP F++ ++E T +
Sbjct: 1926 SGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEA 1985
Query: 980 YT-RAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGL 1038
+ V ++ +V +++ + +VL++ LP + V V ++V G+
Sbjct: 1986 FRLHEVYIDIYDAQVTLQKGH--RVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGV 2043
Query: 1039 TVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQE-ET 1097
V +D N + ++P++Y +CG+CGNFN + D+L + A + F NSW++ +
Sbjct: 2044 QVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDI 2103
Query: 1098 RPGCGA---------TEPGDCPKLDSLVAQQLQSKNECGILADPKGP-FRECHSKLDPQG 1147
P C + E + P + A +++ +C A + P + +C S++D
Sbjct: 2104 DPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCE--AALRAPVWAQCASRIDLTP 2161
Query: 1148 AVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACS 1207
+ DC C G LC AL + A CQ+ G WR+ CPL CP +S Y C
Sbjct: 2162 FLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCL 2221
Query: 1208 YGCPLSCGDLPVPGGC-----GSECHEGCVCDEGFALSGESCLPLASCGC--VHQGTYHP 1260
C SC DL G C S C EGC+C G+ LS + C+P + CGC H G+ P
Sbjct: 2222 PSCSPSCWDL--DGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSI-P 2278
Query: 1261 PGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQ--PSGGSLGCVAVGSSTCQASGD 1318
G++ + GC C C GG + C C CQ + CV+ S C GD
Sbjct: 2279 LGKS-WVSSGCTEKCVC-TGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGD 2336
Query: 1319 PHYTTFDGRRFDFMGTCVYVLAQTCGTRP 1347
P Y TFDG + G YVL +T P
Sbjct: 2337 PRYLTFDGFSYRLQGRMTYVLIKTVDVLP 2365
Score = 384 bits (986), Expect = e-106
Identities = 228/631 (36%), Positives = 309/631 (48%), Gaps = 19/631 (3%)
Query: 779 LSAYAQACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCV 838
+S +A + + +G + + CP N+RYE C ACP SC +P G C
Sbjct: 1017 MSPHAPSTPMTSVILGTTTTSRSSTERCPPNARYESC--ACPASCK---SPRPSCGPLCR 1071
Query: 839 EGCVCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRD 898
EGCVC PGF+ S C+ ASSC C + PG E W C C C + +V C+
Sbjct: 1072 EGCVCNPGFLFSDNHCIQASSCNCFYNNDYYEPGAE-WFSPNCTEHCRCWPGS-RVECQI 1129
Query: 899 KQSCPAGERCSVQNGLLGCYPDR-FGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQ 957
Q C C ++NG GC+P TC GDPHYV+FDGR F FMG CTY+L CG
Sbjct: 1130 SQ-CGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCG- 1187
Query: 958 NAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAA 1017
N+ P FRV +NE +G + VS V V V + + + LV LP +
Sbjct: 1188 NSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGR--RTLVGGQQVTLPAIPS 1245
Query: 1018 DGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLAL 1077
G V + GR ++T+FGL V +D + ++ V S+Y+ LCGLCGN++G+ +D
Sbjct: 1246 KG-VFLGASGRFVELQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLK 1304
Query: 1078 RGGGQAANALAFGNSWQ--EETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGP 1135
G A + GNSWQ ++ C + + P DS + + CG L D GP
Sbjct: 1305 LDGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGP 1364
Query: 1136 FRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPL 1195
F C + C+ D C G LC ++T CQ AG V PWR CP+
Sbjct: 1365 FETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPM 1424
Query: 1196 SCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQ 1255
+CPP+S Y C+ CP +C C C E C C+ GF LSG C+P + CGC+H
Sbjct: 1425 ACPPNSKYSLCAKPCPDTCHSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHP 1484
Query: 1256 -GTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQ 1314
G+Y G+ +Y PGC LC C+ + C+ C E C G GC A G++TC
Sbjct: 1485 AGSYFKVGERWYK-PGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCT 1543
Query: 1315 ASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITV 1374
ASGDPHY TFDG FMGTC YVL + C +R F V N G G + V+ + V
Sbjct: 1544 ASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRG-GILEVSYIKAV 1602
Query: 1375 QVANFTLRLEQRQWKVTVRADGEQGARGLWV 1405
V F L + + V +G + A +W+
Sbjct: 1603 HVTVFDLSISLLR-GCKVMLNGHRVALPVWL 1632
Score = 326 bits (836), Expect = 9e-89
Identities = 220/739 (29%), Positives = 330/739 (44%), Gaps = 64/739 (8%)
Query: 504 SCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELC 563
+C C Q C + G C A VC+ G+ HY +FDG + + C+ +V++C
Sbjct: 1902 TCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVC 1961
Query: 564 SEDDTLPAFSVEAKNE-HRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPV 622
LP F + AK+E G + V + Y V+L +G VL+++++ LP
Sbjct: 1962 HPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQKGHR--VLINSKQVTLPA 2019
Query: 623 SLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADD 682
+ V S ++V + G+ V +D + L + +P + +VCG+CGN+N + D+
Sbjct: 2020 ISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDE 2079
Query: 683 FLTPDGALAPDAVEFASSWKLDDGDYLCEDGC--QNNCPACTPGQAQHYEGDRLCGMLTK 740
+ P +A EF +SWK D D C+ + PA Q ++ G+ L +
Sbjct: 2080 LMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPA---EQQENPSGNCRAADLRR 2136
Query: 741 --------LDGP-FAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGI 791
L P +A C +D PFL C LC GG +LC+ L A+ C G+
Sbjct: 2137 AREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGL 2196
Query: 792 SVGDWRSPANCPLSCPANSRYELCGPACPTS-------CNGAAAPSNCSGRPCVEGCVCL 844
WR+ + CPL CPA S Y C P+C S C GA PS C EGC+C
Sbjct: 2197 KPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPS-----ACAEGCICQ 2251
Query: 845 PGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPA 904
PG+V S CVP S CGC P + W C +C C G + C D + CP+
Sbjct: 2252 PGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGA--IQCGDFR-CPS 2308
Query: 905 GERCSV--QNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALP 962
G C + N C D+ C GDP Y++FDG + G TY+L+ + LP
Sbjct: 2309 GSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVD---VLP 2365
Query: 963 --AFRVLVENEHRGSQTVS--YTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAAD 1018
+LVE ++ S + + V G KV ++ +++V++ +P++ +
Sbjct: 2366 EGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGL--ELVVNNQKMAVPYRPNE 2423
Query: 1019 GQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALR 1078
++V G+ + TDF L V++ +PS Y + GLCGN++ + +D+ L
Sbjct: 2424 -HLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLP 2482
Query: 1079 GGGQAANALAFGNSWQEETRP-------GCGATEPGDCPKLDSLVAQQL----------Q 1121
G N FGNSW+ +T A E G +L Q+
Sbjct: 2483 SGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASN 2542
Query: 1122 SKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLL--PGQSGPL-CDALATYAAACQ 1178
S C +LADP+GPF CH + P+ CV D C P + L C L+ YA CQ
Sbjct: 2543 STQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQ 2602
Query: 1179 AAGATVHPWRSEELCPLSC 1197
AGA + WR LC C
Sbjct: 2603 EAGAALAGWRDRTLCESPC 2621
Score = 150 bits (380), Expect = 7e-36
Identities = 111/377 (29%), Positives = 161/377 (42%), Gaps = 50/377 (13%)
Query: 505 CEGMQCAAGQRCQVVG--GKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVEL 562
C +C +G CQ+ + CV++ + C GDP Y TFDG Y + G +Y +++
Sbjct: 2301 CGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKT 2360
Query: 563 CSEDDTLPA----FSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRS 618
D LP VE +N+ R ++ V Y + V L G ++V+NQ+
Sbjct: 2361 V---DVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLE--LVVNNQKM 2415
Query: 619 RLPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGD 678
+P +E LRV G R + F LVV++ +SLP+ ++ V GLCGNY+ +
Sbjct: 2416 AVPYRPNE-HLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKN 2474
Query: 679 PADDFLTPDGALAPDAVEFASSWKLDDGDYL---------------CEDGCQNNCPA--C 721
+D + P GAL + F +SW++ D L E G + C
Sbjct: 2475 RKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSEC 2534
Query: 722 TPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLS---LCRG 778
+P Q + C +L GPFA CH T+ P PF E CV DLC R C+
Sbjct: 2535 SPEQLAS-NSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQV 2593
Query: 779 LSAYAQACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCV 838
LS YA C E G ++ WR C C N P +G C +
Sbjct: 2594 LSGYAILCQEAGAALAGWRDRTLCESPCLQN----------PCQNDG-----QCREQGAT 2638
Query: 839 EGCVCLPGFVASGGACV 855
C C G+ GG C+
Sbjct: 2639 FTCECEVGY--GGGLCM 2653
>gi|239757284 PREDICTED: similar to Fc fragment of IgG binding protein
[Homo sapiens]
Length = 593
Score = 331 bits (848), Expect = 4e-90
Identities = 209/598 (34%), Positives = 286/598 (47%), Gaps = 83/598 (13%)
Query: 619 RLPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGD 678
+LPV L+ G++R Q G V+E FGL V YD + +++P + Q+CGLCGNYNGD
Sbjct: 2 KLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGD 61
Query: 679 PADDFLTPDGALAPDAVEFASSWK--LDDGDYL----CEDGCQNNCPA--CTPGQAQHYE 730
P DDF P+G+ A +A EF +SW+ + D L C G ++ P+ C P + Y+
Sbjct: 62 PKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQ 121
Query: 731 GDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELG 790
+ CG+L+ GP + CH +DP+ L+ C++DLC+ GG LC + AY AC G
Sbjct: 122 KEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAG 181
Query: 791 ISVGDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGC--------- 841
V WR+ CP+ CP NS YELC C C+ +AP C C EGC
Sbjct: 182 GHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDG-CAEGCQCDSGFLYN 240
Query: 842 --VCLP----GFVASGGACVPASS---------CGC------TFQGLQLAPGQ------- 873
C+P G +G P + C C Q PGQ
Sbjct: 241 GQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSCKPGQVCQPSGG 300
Query: 874 ------EVWADELCQRRCTCNGAT--------------------HQVTCRDKQSCPAGER 907
+V L Q GA H VTCR + E
Sbjct: 301 ILSCVTKVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQ------ET 354
Query: 908 CSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLV--GSCGQNA-ALPAF 964
C Q G C P+ TC GDPHY SFDGR+FDF GTC Y+L G G + L F
Sbjct: 355 CKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPF 414
Query: 965 RVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVF 1024
V +N++RG+ VSY R V V A G +++ ++ G+V V+ VL LP ADG++ V
Sbjct: 415 TVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVT 474
Query: 1025 RQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAA 1084
+ A++ DFGL V+YDWN RV +PSSY A+CGLCGN + +P +D G A
Sbjct: 475 QGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAP 534
Query: 1085 NALAFGNSWQEE-TRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHS 1141
+ +G SW+ P C G CP +Q + +E G L+D K C++
Sbjct: 535 SIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGLDE-GSLSDHKDKIFMCYT 591
Score = 313 bits (801), Expect = 1e-84
Identities = 170/436 (38%), Positives = 212/436 (48%), Gaps = 75/436 (17%)
Query: 1012 LPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDP 1071
LP A+GQ++ + G D V+ TDFGL V YD V VP +Y + +CGLCGN+NGDP
Sbjct: 3 LPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDP 62
Query: 1072 ADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCP----------KLDSLVAQQLQ 1121
DD G QA NA FGNSW EE P P CP K + ++ Q
Sbjct: 63 KDDFQKPNGSQAGNANEFGNSW-EEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQ 121
Query: 1122 SKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAG 1181
+ CG+L+ P GP CH +DPQG ++DC++D CL G LC + Y +ACQAAG
Sbjct: 122 KEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAG 181
Query: 1182 ATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSG 1241
V PWR+E CP+ CPP+SHYE C+ C L C L P C C EGC CD GF +G
Sbjct: 182 GHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNG 241
Query: 1242 ESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGG 1301
++C+P+ CGC H G Y+ P QT C C C G +V C+ SC P + CQPSGG
Sbjct: 242 QACVPIQQCGCYHNGVYYEPEQTVLI-DNCRQQCTCHAGKVVVCQEHSCKPGQVCQPSGG 300
Query: 1302 SLGCVAV-------------------------------------------GSSTCQASGD 1318
L CV TC+ G
Sbjct: 301 ILSCVTKVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQETCKEQGG 360
Query: 1319 -----PHYT------------TFDGRRFDFMGTCVYVLAQT-CG--TRPGLHRFAVLQEN 1358
P+Y +FDGR+FDF GTC YVLA T C + GL F V +N
Sbjct: 361 QGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKN 420
Query: 1359 VAWGNGRVSVTRVITV 1374
GN VS RV+TV
Sbjct: 421 QNRGNPAVSYVRVVTV 436
Score = 187 bits (474), Expect = 8e-47
Identities = 93/238 (39%), Positives = 142/238 (59%), Gaps = 5/238 (2%)
Query: 497 VLSPVEPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCS 556
+LSP C G+ C + C+ GG+ C+ A C GDPHY +FDGR++D GTC+
Sbjct: 338 LLSP--DPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCN 395
Query: 557 YTMVEL-CSEDDT--LPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLV 613
Y + C T L F+V KN++RG+ VSYV +VTV A ++S+ + E+G V V
Sbjct: 396 YVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRV 455
Query: 614 DNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCG 673
+ + LPVS+++GR+ V Q +A++ FGL V+YDW+ ++ ++LP+ + VCGLCG
Sbjct: 456 NGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCG 515
Query: 674 NYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEG 731
N + +P +D + P+G LAP + SW+ D LC D C+ +CP C + + YEG
Sbjct: 516 NMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEG 573
>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
Length = 5765
Score = 318 bits (814), Expect = 3e-86
Identities = 266/974 (27%), Positives = 393/974 (40%), Gaps = 166/974 (17%)
Query: 527 AESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRGSRRV 586
A + VC GD HY TFDG + G C+Y E C F+V+ + GSR V
Sbjct: 71 AHNGRVCSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCRA--AYEDFNVQLRRGLVGSRPV 128
Query: 587 SYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGL 646
V V ++A + + G V L++ QR LP S + L V QSG +++ L
Sbjct: 129 --VTRVVIKAQGLVLEASNGSV---LINGQREELPYSRTG--LLVEQSGD--YIKVSIRL 179
Query: 647 VVTYDWDCQ--LALSLPARFQDQVCGLCGNYNGDPA-DDFLTPDGALAPDAVEFASSWKL 703
V+T+ W+ + L L ++ +Q CGLCG++NG PA ++F + L P ++F + KL
Sbjct: 180 VLTFLWNGEDSALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLTP--LQFGNLQKL 237
Query: 704 DDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVY 763
D C D CT + + +C T L FA CH +D +L C
Sbjct: 238 DGPTEQCPDPLPLPAGNCT-------DEEGICHR-TLLGPAFAECHALVDSTAYLAACAQ 289
Query: 764 DLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSC 823
DLC C Y++ C G +WR P CP +CP N +++ CG C +C
Sbjct: 290 DLCRCP---TCPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTC 346
Query: 824 NGAAAPSNCSGRPCVEGCVCLPGFVAS------GGACVPASSCGCTFQGLQLAPGQEVWA 877
+ C CV+GC C PG + C+P C CT G +PG
Sbjct: 347 SNPQRAQLCEDH-CVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHGGRTYSPGTSF-- 403
Query: 878 DELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFD 937
+ C CTC+G Q C+D CP GTC G H ++D
Sbjct: 404 NTTCSS-CTCSGGLWQ--CQDLP-CP-------------------GTCSVQGGAHISTYD 440
Query: 938 GRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRG-SQTVSYTRAVRVEARGVKVAVR 996
+ +D G C+Y+L C ++ F VL E G + + +AV + G A+R
Sbjct: 441 EKLYDLHGDCSYVLSKKCADSS----FTVLAELRKCGLTDNENCLKAVTLSLDGGDTAIR 496
Query: 997 REYPGQVLVDDVLQYLPFQAADGQVQVFRQGRD-AVVRTDFGLTVTYDWNA--RVTAKVP 1053
+ G V ++ + LP AA+ + +F VV+T GL + +V ++
Sbjct: 497 VQADGGVFLNSIYTQLPLSAAN--ITLFTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLD 554
Query: 1054 SSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPKLD 1113
++ +CGLCGNFN + ADD G A AF N+W+ + C
Sbjct: 555 PAHQGQMCGLCGNFNQNQADDFTALSGVVEATGAAFANTWKAQA--ACANARNSFEDPCS 612
Query: 1114 SLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATY 1173
V + +++ C L DP F CHS ++P+ +C++D C LC AL++Y
Sbjct: 613 LSVENENYARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNCERSEDCLCAALSSY 672
Query: 1174 AAACQAAGATVHPWRSEELCP---LSCPPHSHYEACSYGCPLSC---GDLPVPGGCGSEC 1227
AC A G + WR + +C +CP Y C +C + V
Sbjct: 673 VHACAAKGVQLSDWR-DGVCTKYMQNCPKSQRYAYVVDACQPTCRGLSEADVTCSVSFVP 731
Query: 1228 HEGCVCDEG-FALSGESCLPLASCGCVHQGTYHPPGQTFY-------------------- 1266
+GC C G F +C+P C C GT PG+ +
Sbjct: 732 VDGCTCPAGTFLNDAGACVPAQECPCYAHGTVLAPGEVVHDEGAVCSCTGGKLSCLGASL 791
Query: 1267 ----------------------PGPGCDSLCHCQEGGLVSCESSSCGPHEACQP---SGG 1301
PG C CH + V C S+ C C P S G
Sbjct: 792 QKSTGCAAPMVYLDCSNSSAGTPGAECLRSCHTLD---VGCFSTHCVSGCVCPPGLVSDG 848
Query: 1302 SLGCVA--------------------VGSSTCQ------------------ASGDPHYTT 1323
S GC+A V +TC A GD H+ T
Sbjct: 849 SGGCIAEEDCPCVHNEATYKPGETIRVDCNTCTCRNRRWECSHRLCLGTCVAYGDGHFIT 908
Query: 1324 FDGRRFDFMGTCVYVLAQT-CGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLR 1382
FDG R+ F G+C Y+LAQ CG F ++ EN+ G + ++ I + V ++ L
Sbjct: 909 FDGDRYSFEGSCEYILAQDYCGDNTTHGTFRIVTENIPCGTTGTTCSKAIKLFVESYELI 968
Query: 1383 LEQRQWKVTVRADG 1396
L++ +K R G
Sbjct: 969 LQEGTFKAVARGPG 982
Score = 251 bits (640), Expect = 5e-66
Identities = 246/946 (26%), Positives = 369/946 (39%), Gaps = 174/946 (18%)
Query: 516 CQVVGGKAGCV-AESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSV 574
C GG C C QG H +T+D + YD+ G CSY + + C++ +F+V
Sbjct: 410 CTCSGGLWQCQDLPCPGTCSVQGGAHISTYDEKLYDLHGDCSYVLSKKCADS----SFTV 465
Query: 575 EAKNEHRG-SRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQ 633
A+ G + + + VT+ ++ G V +++ ++LP+S + L
Sbjct: 466 LAELRKCGLTDNENCLKAVTLSLDGGDTAIRVQADGGVFLNSIYTQLPLSAANITLFT-P 524
Query: 634 SGPRAVVELVFGLVVTYDWD--CQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALA 691
S VV+ GL + Q+ + L Q Q+CGLCGN+N + ADDF G +
Sbjct: 525 SSFFIVVQTGLGLQLLVQLVPLMQVFVRLDPAHQGQMCGLCGNFNQNQADDFTALSGVVE 584
Query: 692 PDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQ--AQHYEGDRLCGMLTKLDGPFAVCH 749
FA++WK + ++ C + A+H+ C LT + F+ CH
Sbjct: 585 ATGAAFANTWKAQAACANARNSFEDPCSLSVENENYARHW-----CSRLTDPNSAFSRCH 639
Query: 750 DTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSP--ANCPLSCP 807
++P+PF C++D C LC LS+Y AC G+ + DWR +CP
Sbjct: 640 SIINPKPFHSNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLSDWRDGVCTKYMQNCP 699
Query: 808 ANSRYELCGPACPTSCNG-AAAPSNCS-GRPCVEGCVCLPG-FVASGGACVPASSCGCTF 864
+ RY AC +C G + A CS V+GC C G F+ GACVPA C C
Sbjct: 700 KSQRYAYVVDACQPTCRGLSEADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQECPCYA 759
Query: 865 QGLQLAPGQEVWADELCQRRCT-----CNGATHQ-----------VTCRDKQSCPAGERC 908
G LAPG EV DE CT C GA+ Q + C + + G C
Sbjct: 760 HGTVLAPG-EVVHDEGAVCSCTGGKLSCLGASLQKSTGCAAPMVYLDCSNSSAGTPGAEC 818
Query: 909 -------------------------SVQNGLLGCYPDRFGTCQGSG-----------DPH 932
V +G GC + C + D +
Sbjct: 819 LRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKPGETIRVDCN 878
Query: 933 YVSFDGRRFD-----FMGTCT--------------YLLVGS---------CGQNAALPAF 964
+ RR++ +GTC Y GS CG N F
Sbjct: 879 TCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNTTHGTF 938
Query: 965 RVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQA------AD 1018
R++ EN G+ + ++A+++ ++ +LQ F+A D
Sbjct: 939 RIVTENIPCGTTGTTCSKAIKLFVESYEL--------------ILQEGTFKAVARGPGGD 984
Query: 1019 GQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALR 1078
++ G V+ T G+ V++D V ++ Y +CGLCGNF+ + +D A R
Sbjct: 985 PPYKIRYMGIFLVIET-HGMAVSWDRKTSVFIRLHQDYKGRVCGLCGNFDDNAINDFATR 1043
Query: 1079 GGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQ---SKNECGILADPKGP 1135
+AL FGNSW + P C P D A + ++ +C IL P
Sbjct: 1044 SRSVVGDALEFGNSW--KLSPSC----PDALAPKDPCTANPFRKSWAQKQCSILHGP--T 1095
Query: 1136 FRECHSKLDPQGAVRDCVYDRCLLP--GQSGPLCDALATYAAACQAAGATVHPWRSEELC 1193
F C S++D CV D C G C A+A YA AC AG V WR+ + C
Sbjct: 1096 FAACRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACHDAGLCV-SWRTPDTC 1154
Query: 1194 PLSCP---PHS----HYEACSYGCPLSCGD------LPVPGGCGSECHEGCVCDEGFALS 1240
PL C PH HY+ C C +C + + +PG G C+ C + F +
Sbjct: 1155 PLFCDFYNPHGGCEWHYQPCGAPCLKTCRNPSGHCLVDLPGLEG--CYPKCPPSQPF-FN 1211
Query: 1241 GESCLPLASCGCVHQ-GTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPS 1299
+ +A CGC + G Y+ G C S C+C G+ S
Sbjct: 1212 EDQMKCVAQCGCYDKDGNYYDVGARVPTAENCQS-CNCTPSGIQCAHSLE---------- 1260
Query: 1300 GGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGT 1345
C + D Y T DG +G C+ + + GT
Sbjct: 1261 ----ACTCTYEDRTYSYQDVIYNTTDG-----LGACLIAICGSNGT 1297
Score = 145 bits (366), Expect = 3e-34
Identities = 171/644 (26%), Positives = 253/644 (39%), Gaps = 138/644 (21%)
Query: 406 AYVVKSV-PGCEGVALVVAQTKAISGLTIDGHAVGAKL----TWEAVPGSE---FSYAEV 457
AYVV + P C G++ T ++S + +DG A VP E +++ V
Sbjct: 705 AYVVDACQPTCRGLSEADV-TCSVSFVPVDGCTCPAGTFLNDAGACVPAQECPCYAHGTV 763
Query: 458 ELGTADMIHTAEATTN-----LGLLTFGLAKAIGYAT---------------AADCGRTV 497
L +++H A + L L L K+ G A A+C R+
Sbjct: 764 -LAPGEVVHDEGAVCSCTGGKLSCLGASLQKSTGCAAPMVYLDCSNSSAGTPGAECLRSC 822
Query: 498 LSPVEPSCEGMQCAAGQRCQ---VVGGKAGCVAE----------------------STAV 532
+ ++ C C +G C V G GC+AE +T
Sbjct: 823 HT-LDVGCFSTHCVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKPGETIRVDCNTCT 881
Query: 533 CR----------------AQGDPHYTTFDGRRYDMMGTCSYTMVE-LCSEDDTLPAFSVE 575
CR A GD H+ TFDG RY G+C Y + + C ++ T F +
Sbjct: 882 CRNRRWECSHRLCLGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNTTHGTFRIV 941
Query: 576 AKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSG 635
+N G+ + + + S+ + L G V +R P ++R G
Sbjct: 942 TENIPCGTTGTTCSKAIKLFVESYELILQEGTFKAV------ARGPGGDPPYKIRYM--G 993
Query: 636 PRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAV 695
V+E G+ V++D + + L ++ +VCGLCGN++ + +DF T ++ DA+
Sbjct: 994 IFLVIE-THGMAVSWDRKTSVFIRLHQDYKGRVCGLCGNFDDNAINDFATRSRSVVGDAL 1052
Query: 696 EFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGP-FAVCHDTLDP 754
EF +SWKL C D P CT + + C + L GP FA C +D
Sbjct: 1053 EFGNSWKLSPS---CPDALAPKDP-CTANPFRKSWAQKQCSI---LHGPTFAACRSQVDS 1105
Query: 755 RPFLEQCVYDLCVV--GGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSCP----- 807
+ E CV D C GG+ C ++AYAQAC + G+ V WR+P CPL C
Sbjct: 1106 TKYYEACVNDACACDSGGDCECFCTAVAAYAQACHDAGLCV-SWRTPDTCPLFCDFYNPH 1164
Query: 808 --ANSRYELCGPACPTSCNGAAAPSNC-SGRPCVEGCV--CLPG---FVASGGACVPASS 859
Y+ CG C +C + +C P +EGC C P F CV +
Sbjct: 1165 GGCEWHYQPCGAPCLKTCRNPS--GHCLVDLPGLEGCYPKCPPSQPFFNEDQMKCV--AQ 1220
Query: 860 CGC-TFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGC- 917
CGC G G V E CQ C C P+G +C+ C
Sbjct: 1221 CGCYDKDGNYYDVGARVPTAENCQ-SCNCT--------------PSGIQCAHSLEACTCT 1265
Query: 918 YPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL 961
Y DR + Q D Y + DG +G C L+ CG N +
Sbjct: 1266 YEDRTYSYQ---DVIYNTTDG-----LGAC---LIAICGSNGTI 1298
Score = 115 bits (288), Expect = 3e-25
Identities = 113/405 (27%), Positives = 161/405 (39%), Gaps = 62/405 (15%)
Query: 528 ESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTM----------VELCSEDDTLPAFSVEAK 577
E +C G HY+TFDG Y G C+Y + + L ++ A + A
Sbjct: 5073 ECECICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTASATAAA 5132
Query: 578 NEHRGSRRVSYVGLVTVRAYSHSVSLTRG-EVGFVLVDNQRSRLPVS--LSEGRLRVYQS 634
+ + Y + V +V++ G E G +L D ++PVS S+ + V
Sbjct: 5133 ARCPRALSIHYKSMDIVL----TVTMVHGKEEGLILFD----QIPVSSGFSKNGVLVSVL 5184
Query: 635 GPRAV-VEL-VFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAP 692
G + V++ G+ VT++ A + F + G CG + DD L DG A
Sbjct: 5185 GTTTMRVDIPALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAA 5244
Query: 693 DAVEFASSWKLDDGDYLCEDGC---------------QNNCPACTPGQAQHYEGDRLCGM 737
+ A +W + D +DGC ++ P TP Q LC +
Sbjct: 5245 SCKDMAKTWLVPDSR---KDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQ-----PLCDL 5296
Query: 738 LTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWR 797
+ L FA CH+ + P PF C+ D C G C+ L AYA+ C G+ DWR
Sbjct: 5297 M--LSQVFAECHNLVPPGPFFNACISDHC--RGRLEVPCQSLEAYAELCRARGV-CSDWR 5351
Query: 798 SPAN--CPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPG---FVASGG 852
C L+CP Y+ CGP P +CN G EGC C F A G
Sbjct: 5352 GATGGLCDLTCPPTKVYKPCGPIQPATCNSRNQSPQLEG--MAEGCFCPEDQILFNAHMG 5409
Query: 853 ACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCR 897
CV A C G PG E W CQ C C+ + V C+
Sbjct: 5410 ICVQACPC-VGPDGFPKFPG-ERWVSN-CQ-SCVCDEGSVSVQCK 5450
Score = 93.6 bits (231), Expect = 1e-18
Identities = 126/500 (25%), Positives = 176/500 (35%), Gaps = 84/500 (16%)
Query: 841 CVCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQ-RRCTCNGAT-------- 891
C P V+S P+ + GC + L E W E C RC +
Sbjct: 4989 CPTSPPPVSSAPLSSPSPAPGCD-NAIPLRQVNETWTLENCTVARCVGDNRVVLLDPKPV 5047
Query: 892 HQVTCRDK----------QSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRF 941
VTC +K Q C C C G HY +FDG +
Sbjct: 5048 ANVTCVNKHLPIKVSDPSQPCDFHYECEC-------------ICSMWGGSHYSTFDGTSY 5094
Query: 942 DFMGTCTYLLVGSCGQNAALPAFRVLVENEH-RGSQTVSYTRAVRVEARGVK-------- 992
F G CTY+L+ +A + ++N + S T + R R + K
Sbjct: 5095 TFRGNCTYVLMREI--HARFGNLSLYLDNHYCTASATAAAARCPRALSIHYKSMDIVLTV 5152
Query: 993 VAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYD---WNARVT 1049
V + G +L D + F V V V G++VT++ + AR+
Sbjct: 5153 TMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMRVDIPALGVSVTFNGQVFQARLP 5212
Query: 1050 AKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSW--QEETRPGCGATEPG 1107
+ + E CG C N + DD R G AA+ +W + + GC A P
Sbjct: 5213 YSLFHNNTEGQCGTCTN---NQRDDCLQRDGTTAASCKDMAKTWLVPDSRKDGCWA--PT 5267
Query: 1108 DCPKLDSLVAQQLQSKNECGILADP------KGPFRECHSKLDPQGAVRDCVYDRCLLPG 1161
P S A + P F ECH+ + P C+ D C G
Sbjct: 5268 GTPPTASPAAPVSSTPTPTPCPPQPLCDLMLSQVFAECHNLVPPGPFFNACISDHC--RG 5325
Query: 1162 QSGPLCDALATYAAACQAAGATVHPWRSEE--LCPLSCPPHSHYEACSYGCPLSC---GD 1216
+ C +L YA C+A G WR LC L+CPP Y+ C P +C
Sbjct: 5326 RLEVPCQSLEAYAELCRARG-VCSDWRGATGGLCDLTCPPTKVYKPCGPIQPATCNSRNQ 5384
Query: 1217 LPVPGGCGSECHEGCVCDEGFAL-SGESCLPLASCGCVHQGTYHPPGQTFYPG----PGC 1271
P G EGC C E L + + + +C CV P G +PG C
Sbjct: 5385 SPQLEGMA----EGCFCPEDQILFNAHMGICVQACPCV-----GPDGFPKFPGERWVSNC 5435
Query: 1272 DSLCHCQEGGL-VSCESSSC 1290
S C C EG + V C+ C
Sbjct: 5436 QS-CVCDEGSVSVQCKPLPC 5454
Score = 40.0 bits (92), Expect = 0.017
Identities = 40/134 (29%), Positives = 51/134 (38%), Gaps = 12/134 (8%)
Query: 1269 PGCDSLCHCQEGGLVSCESS---SCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFD 1325
P ++ H +GG + + S P PS L A C GD HY TFD
Sbjct: 31 PSWENAGHTMDGGAPTSSPTRRVSFVPPVTVFPSLSPLN-PAHNGRVCSTWGDFHYKTFD 89
Query: 1326 GRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVIT-VQVANFTLRLE 1384
G F F G C YV ++ C R A NV G V V+T V + L LE
Sbjct: 90 GDVFRFPGLCNYVFSEHC-------RAAYEDFNVQLRRGLVGSRPVVTRVVIKAQGLVLE 142
Query: 1385 QRQWKVTVRADGEQ 1398
V + E+
Sbjct: 143 ASNGSVLINGQREE 156
Score = 39.3 bits (90), Expect = 0.028
Identities = 23/66 (34%), Positives = 28/66 (42%), Gaps = 13/66 (19%)
Query: 1283 VSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQT 1342
VS S C H C+ C+ C G HY+TFDG + F G C YVL +
Sbjct: 5061 VSDPSQPCDFHYECE-------CI------CSMWGGSHYSTFDGTSYTFRGNCTYVLMRE 5107
Query: 1343 CGTRPG 1348
R G
Sbjct: 5108 IHARFG 5113
>gi|169202626 PREDICTED: similar to mucin 5, partial [Homo sapiens]
Length = 2013
Score = 316 bits (810), Expect = 9e-86
Identities = 263/968 (27%), Positives = 391/968 (40%), Gaps = 154/968 (15%)
Query: 522 KAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHR 581
+A A + VC G HY TFDG + G C+Y E C F+++ +
Sbjct: 70 RASNPAHNGRVCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGA--AYEDFNIQLRRSQE 127
Query: 582 GSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVE 641
+ + V ++ + LT+G V LV+ LP S+ + + QS VE
Sbjct: 128 SAAPT--LSRVLMKVDGVVIQLTKGSV---LVNGHPVLLP--FSQSGVLIQQSSSYTKVE 180
Query: 642 LVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPA-DDFLTPDGALAPDAVEFASS 700
GLV+ ++ D L L L ++ ++ CGLCG++NG P + L+ + L P +EF +
Sbjct: 181 ARLGLVLMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTP--MEFGNL 238
Query: 701 WKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQ 760
K+DD C+D C+ G E L G L F+ C +D +LE
Sbjct: 239 QKMDDPTEQCQDPVPEPPRNCSTGFGICEE--LLHGQL------FSGCVALVDVGSYLEA 290
Query: 761 CVYDLCVVGGERL--SLCRGLSAYAQACLELGISVGDWRSPANCPLSCPANSRYELCGPA 818
C DLC L +C L+ Y++ C G DWR P CP CP N +Y C
Sbjct: 291 CRQDLCFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSP 350
Query: 819 CPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASG---GACVPASSCGCTFQGLQLAPGQEV 875
C +C+ C CV GC C G V CVP S C C + G APG
Sbjct: 351 CADTCSNQEHSRACEDH-CVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATY 409
Query: 876 WADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVS 935
D C CTC+G + +C++ CP GTC G H+ +
Sbjct: 410 STD--CTN-CTCSGG--RWSCQEVP-CP-------------------GTCSVLGGAHFST 444
Query: 936 FDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRG-SQTVSYTRAVRVEARGVKVA 994
FDG+++ G C+Y+L C +A F VL E G + + + ++V + GV+
Sbjct: 445 FDGKQYTVHGDCSYVLTKPCDSSA----FTVLAELRRCGLTDSETCLKSVTLSLDGVQTV 500
Query: 995 VRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVV-RTDFGLTVTYDW--NARVTAK 1051
V + G+V ++ + LP AA+ V +FR ++ +T GL + ++ +
Sbjct: 501 VVIKASGEVFLNQIYTQLPISAAN--VTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQ 558
Query: 1052 VPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPK 1111
+ CGLCGNFN ADD G A A AF N+++ T+ C
Sbjct: 559 LAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFK--TQAACPNIRNSFEDP 616
Query: 1112 LDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALA 1171
V + +++ C L D GPF CH+ + P +C++D C LC AL+
Sbjct: 617 CSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNCERSEDCLCAALS 676
Query: 1172 TYAAACQAAGATVHPWRS------EELCPLSCPPHSHYEACSYGC-PLSCGDLPVPGGCG 1224
+Y AC A G + WR CP S H H C C LS GD+ G
Sbjct: 677 SYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVSTCQPTCRSLSEGDITC--SVG 734
Query: 1225 SECHEGCVCDEGFALSGE-SCLPLASCGCVHQGTYHPPGQTFY----------------- 1266
+GC+C +G L C+ ++C C H+G+ P G++ +
Sbjct: 735 FIPVDGCICPKGTFLDDTGKCVQASNCPCYHRGSMIPNGESVHDSGAICTCTHGKLSCIG 794
Query: 1267 ------------------------PGPGCDSLCHC-----------------------QE 1279
G GC CH E
Sbjct: 795 GQAPAPVCAAPMVFFDCRNATPGDTGAGCQKSCHTLDMTCYSPQCVPGCVCPDGLVADGE 854
Query: 1280 GGLVSCESSSCGPHEACQPSGGSL--GCVAVGS-------------STCQASGDPHYTTF 1324
GG ++ E C +EA +G ++ GC +TC GD HY TF
Sbjct: 855 GGCITAEDCPCVHNEASYRAGQTIRVGCNTCTCDSRMWRCTDDPCLATCAVYGDGHYLTF 914
Query: 1325 DGRRFDFMGTCVYVLAQT-CGTRPGLH-RFAVLQENVAWGNGRVSVTRVITVQVANFTLR 1382
DG+ + F G C Y L Q CG + F V+ ENV G + ++ I + + F L+
Sbjct: 915 DGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTTGTTCSKAIKIFLGGFELK 974
Query: 1383 LEQRQWKV 1390
L + +V
Sbjct: 975 LSHGKVEV 982
Score = 169 bits (427), Expect = 2e-41
Identities = 153/544 (28%), Positives = 219/544 (40%), Gaps = 96/544 (17%)
Query: 816 GPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASG-GACVPASSCGCTFQGLQLAPGQE 874
G C SC+ C CV GCVC G VA G G C+ A C C GQ
Sbjct: 820 GAGCQKSCH--TLDMTCYSPQCVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQT 877
Query: 875 VWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDR-FGTCQGSGDPHY 933
+ R CN C+ + + C D TC GD HY
Sbjct: 878 I--------RVGCN------------------TCTCDSRMWRCTDDPCLATCAVYGDGHY 911
Query: 934 VSFDGRRFDFMGTCTYLLVGS-CG-QNAALPAFRVLVENEHRGSQTVSYTRAVRVEARGV 991
++FDG+ + F G C Y LV + CG +++ +FRV+ EN G+ + ++A+++ G
Sbjct: 912 LTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTTGTTCSKAIKIFLGGF 971
Query: 992 KVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAK 1051
++ + +V+ D Q +P+ + + G VV TD GL + +D +
Sbjct: 972 ELKLSHGKV-EVIGTDESQEVPYT-------IRQMGIYLVVDTDIGLVLLWDKKTSIFIN 1023
Query: 1052 VPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPK 1111
+ + +CGLCGNF+ +D A R + L FGNSW + P C P
Sbjct: 1024 LSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSW--KLSPSC----PDALAP 1077
Query: 1112 LDSLVAQQLQ---SKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLP--GQSGPL 1166
D A + ++ +C IL P F CH+ ++P CV D C G
Sbjct: 1078 KDPCTANPFRKSWAQKQCSILHGP--TFAACHAHVEPARYYEACVNDACACDSGGDCECF 1135
Query: 1167 CDALATYAAACQAAGATVHPWRSEELCPLSCPPHS-------HYEACSYGCPLSC----G 1215
C A+A YA AC G V WR+ +CPL C ++ HY+ C C +C G
Sbjct: 1136 CTAVAAYAQACHEVGLCV-SWRTPSICPLFCDYYNPEGQCEWHYQPCGVPCLRTCRNPRG 1194
Query: 1216 DL--PVPG--GCGSEC-HEGCVCDEGFALSGESC-LPLASCGCVHQGTYHPPGQTFYPGP 1269
D V G GC +C E + DE +C P C G + PG
Sbjct: 1195 DCLRDVWGLEGCYPKCPPEAPIFDEDKMQCVATCPTPPLPPRCHVHGKSYRPGAVVPSDK 1254
Query: 1270 GCDSLCHCQEGGLVSCESSSCGPHEAC----------------QPSGGSLGCVAVGSSTC 1313
C S C C E G V C + EAC + G+ GC+ S+ C
Sbjct: 1255 NCQS-CLCTERG-VECTYKA----EACVCTYNGQRFHPGDVIYHTTDGTGGCI---SARC 1305
Query: 1314 QASG 1317
A+G
Sbjct: 1306 GANG 1309
Score = 155 bits (391), Expect = 4e-37
Identities = 132/479 (27%), Positives = 193/479 (40%), Gaps = 57/479 (11%)
Query: 925 CQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRV-LVENEHRGSQTVSYTRA 983
C G HY +FDG F F G C Y+ CG AA F + L ++ + T+S
Sbjct: 81 CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCG--AAYEDFNIQLRRSQESAAPTLS---R 135
Query: 984 VRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYD 1043
V ++ GV + + + G VLV+ LPF + +Q + V GL + ++
Sbjct: 136 VLMKVDGVVIQLTK---GSVLVNGHPVLLPFSQSGVLIQ--QSSSYTKVEARLGLVLMWN 190
Query: 1044 WNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGA 1103
+ + ++ + YA CGLCG+FNG P L + FGN Q+ P
Sbjct: 191 HDDSLLLELDTKYANKTCGLCGDFNGMPVVS-ELLSHNTKLTPMEFGNL-QKMDDPTEQC 248
Query: 1104 TEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQS 1163
+P P + + + G L F C + +D + C D C
Sbjct: 249 QDPVPEPPRNCSTGFGICEELLHGQL------FSGCVALVDVGSYLEACRQDLCFCEDTD 302
Query: 1164 --GPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPVPG 1221
+C LA Y+ C AG WR + CP CP + Y C C +C +
Sbjct: 303 LLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEHSR 362
Query: 1222 GCGSECHEGCVCDEGFALSG---ESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQ 1278
C C GC C EG L C+P++ C CV+ G + PG T+ C + C C
Sbjct: 363 ACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATY--STDCTN-CTC- 418
Query: 1279 EGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYV 1338
GG SC+ C TC G H++TFDG+++ G C YV
Sbjct: 419 SGGRWSCQEVPC-------------------PGTCSVLGGAHFSTFDGKQYTVHGDCSYV 459
Query: 1339 LAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVRADGE 1397
L + C + F VL E R +T T + + TL L+ Q V ++A GE
Sbjct: 460 LTKPCDS----SAFTVLAE-----LRRCGLTDSETC-LKSVTLSLDGVQTVVVIKASGE 508
Score = 155 bits (391), Expect = 4e-37
Identities = 118/381 (30%), Positives = 167/381 (43%), Gaps = 44/381 (11%)
Query: 531 AVCRAQGDPHYTTFDGRRYDMMGTCSYTMVE--LCSEDDTLPAFSVEAKNEHRGSRRVSY 588
A C GD HY TFDG+ Y G C YT+V+ +D T +F V +N G+ +
Sbjct: 901 ATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTTGTTC 960
Query: 589 VGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVV 648
+ + + L+ G+V + D + E + Q G VV+ GLV+
Sbjct: 961 SKAIKIFLGGFELKLSHGKVEVIGTDESQ--------EVPYTIRQMGIYLVVDTDIGLVL 1012
Query: 649 TYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDY 708
+D + ++L F+ +VCGLCGN++ +DF T ++ D +EF +SWKL
Sbjct: 1013 LWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWKLSPS-- 1070
Query: 709 LCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGP-FAVCHDTLDPRPFLEQCVYDLCV 767
C D P CT + + C + L GP FA CH ++P + E CV D C
Sbjct: 1071 -CPDALAPKDP-CTANPFRKSWAQKQCSI---LHGPTFAACHAHVEPARYYEACVNDACA 1125
Query: 768 V--GGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSC-------PANSRYELCGPA 818
GG+ C ++AYAQAC E+G+ V WR+P+ CPL C Y+ CG
Sbjct: 1126 CDSGGDCECFCTAVAAYAQACHEVGLCV-SWRTPSICPLFCDYYNPEGQCEWHYQPCGVP 1184
Query: 819 CPTSCNGAAAPSNCSGRPC--VEGCV--C---LPGFVASGGACV-----PASSCGCTFQG 866
C +C P R +EGC C P F CV P C G
Sbjct: 1185 CLRTCRN---PRGDCLRDVWGLEGCYPKCPPEAPIFDEDKMQCVATCPTPPLPPRCHVHG 1241
Query: 867 LQLAPGQEVWADELCQRRCTC 887
PG V +D+ CQ C C
Sbjct: 1242 KSYRPGAVVPSDKNCQ-SCLC 1261
Score = 151 bits (381), Expect = 5e-36
Identities = 128/453 (28%), Positives = 186/453 (41%), Gaps = 82/453 (18%)
Query: 480 GLAKAIGYATAADCGRTVLSPVEPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDP 539
G A A G + DC S SC+ + C C V+GG
Sbjct: 400 GAAYAPGATYSTDCTNCTCSGGRWSCQEVPCPG--TCSVLGGA----------------- 440
Query: 540 HYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRG---------SRRVSYVG 590
H++TFDG++Y + G CSY + + C AF+V A+ G S +S G
Sbjct: 441 HFSTFDGKQYTVHGDCSYVLTKPCDSS----AFTVLAELRRCGLTDSETCLKSVTLSLDG 496
Query: 591 LVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVV-------ELV 643
+ TV S G V ++ ++LP+S + + +++ ++ +L
Sbjct: 497 VQTVVVIKAS--------GEVFLNQIYTQLPISAAN--VTIFRPSTFFIIAQTSLGLQLN 546
Query: 644 FGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKL 703
LV T QL + L + + Q CGLCGN+N ADDF T G + A F +++K
Sbjct: 547 LQLVPTM----QLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKT 602
Query: 704 DDGDYLCEDGCQNNCPACTPGQ--AQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQC 761
+ ++ C + AQH+ C LT DGPF CH + P + C
Sbjct: 603 QAACPNIRNSFEDPCSLSVENEKYAQHW-----CSQLTDADGPFGRCHAAVKPGTYYSNC 657
Query: 762 VYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRS------PANCPLSCPANSRYELC 815
++D C LC LS+Y AC G+ +G WR CP S + C
Sbjct: 658 MFDTCNCERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVSTC 717
Query: 816 GPACPTSCNGAAAPSNCS-GRPCVEGCVCLPG-FVASGGACVPASSCGCTFQGLQLAPGQ 873
P C + G CS G V+GC+C G F+ G CV AS+C C +G + G+
Sbjct: 718 QPTCRSLSEG---DITCSVGFIPVDGCICPKGTFLDDTGKCVQASNCPCYHRGSMIPNGE 774
Query: 874 EVWADELCQRRCTCNGATHQVTCRDKQSCPAGE 906
V CTC TH K SC G+
Sbjct: 775 SVHDSGAI---CTC---TH-----GKLSCIGGQ 796
>gi|89191868 von Willebrand factor preproprotein [Homo sapiens]
Length = 2813
Score = 314 bits (805), Expect = 3e-85
Identities = 231/790 (29%), Positives = 325/790 (41%), Gaps = 90/790 (11%)
Query: 507 GMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSED 566
G CA G R + STA C G TFDG Y G CSY + C +
Sbjct: 19 GTLCAEGTRGR----------SSTARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKR 68
Query: 567 DTLPAFSV--EAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSL 624
+FS+ + +N R S V + + + ++T+G+ QR +P +
Sbjct: 69 ----SFSIIGDFQNGKRVSLSVYLGEFFDIHLFVNG-TVTQGD--------QRVSMPYA- 114
Query: 625 SEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFL 684
S+G ++G + +G V D + L R+ ++ CGLCGN+N DDF+
Sbjct: 115 SKGLYLETEAGYYKLSGEAYGFVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFM 174
Query: 685 TPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGP 744
T +G L D +FA+SW L G+ CE + +C + +G L K
Sbjct: 175 TQEGTLTSDPYDFANSWALSSGEQWCERASPPSS-SCNISSGEMQKGLWEQCQLLKSTSV 233
Query: 745 FAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPL 804
FA CH +DP PF+ C LC G C L YA+ C + G+ + W + C
Sbjct: 234 FARCHPLVDPEPFVALCEKTLCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSP 293
Query: 805 SCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGCTF 864
CPA Y C C +C C R CV+GC C G + G CV ++ C C
Sbjct: 294 VCPAGMEYRQCVSPCARTCQSLHINEMCQER-CVDGCSCPEGQLLDEGLCVESTECPCVH 352
Query: 865 QGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGT 924
G + PG + D CN CR+ Q + E C G
Sbjct: 353 SGKRYPPGTSLSRD--------CN----TCICRNSQWICSNEECP-------------GE 387
Query: 925 CQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVEN-EHRGSQTVSYTRA 983
C +G H+ SFD R F F G C YLL C + +F +++E + + TR+
Sbjct: 388 CLVTGQSHFKSFDNRYFTFSGICQYLLARDCQDH----SFSIVIETVQCADDRDAVCTRS 443
Query: 984 VRVEARGV-KVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTY 1042
V V G+ V+ ++ V +D LP D ++Q A VR +G +
Sbjct: 444 VTVRLPGLHNSLVKLKHGAGVAMDGQDVQLPLLKGDLRIQ---HTVTASVRLSYGEDLQM 500
Query: 1043 DWN--ARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPG 1100
DW+ R+ K+ YA CGLCGN+NG+ DD G FGN+W+
Sbjct: 501 DWDGRGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLH---- 556
Query: 1101 CGATEPGDCPKLDSLVAQQLQ--------SKNECGILADPKGPFRECHSKLDPQGAVRDC 1152
GDC L + S+ C +L P F CH + P +R+C
Sbjct: 557 ------GDCQDLQKQHSDPCALNPRMTRFSEEACAVLTSP--TFEACHRAVSPLPYLRNC 608
Query: 1153 VYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPL 1212
YD C LC ALA+YAAAC G V WR C L+CP Y C C L
Sbjct: 609 RYDVCSCSDGRECLCGALASYAAACAGRGVRV-AWREPGRCELNCPKGQVYLQCGTPCNL 667
Query: 1213 SCGDLPVPG-GCGSECHEGCVCDEGFALSGE-SCLPLASCGCVHQGTYHPPGQTFYPGPG 1270
+C L P C C EGC C G + C+P A C C + G P F
Sbjct: 668 TCRSLSYPDEECNEACLEGCFCPPGLYMDERGDCVPKAQCPCYYDGEIFQPEDIF---SD 724
Query: 1271 CDSLCHCQEG 1280
++C+C++G
Sbjct: 725 HHTMCYCEDG 734
Score = 178 bits (451), Expect = 4e-44
Identities = 151/530 (28%), Positives = 218/530 (41%), Gaps = 83/530 (15%)
Query: 799 PANCPLSCPA-NSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPA 857
P L CPA N R E G C +C C CV GC+C PG V CV
Sbjct: 769 PPMVKLVCPADNLRAE--GLECTKTCQNYDL--ECMSMGCVSGCLCPPGMVRHENRCVAL 824
Query: 858 SSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGC 917
C C QG + APG+ V + CN CRD++ C
Sbjct: 825 ERCPCFHQGKEYAPGETV--------KIGCNTCV----CRDRKWNCTDHVCDA------- 865
Query: 918 YPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGS-CGQNAALPAFRVLVENEHRGSQ 976
TC G HY++FDG ++ F G C Y+LV CG N FR+LV N+
Sbjct: 866 ------TCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPG--TFRILVGNKGCSHP 917
Query: 977 TVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDF 1036
+V + V + G ++ + + G+V V ++ + +V GR ++
Sbjct: 918 SVKCKKRVTILVEGGEIEL---FDGEVNVKRPMK------DETHFEVVESGRYIILLLGK 968
Query: 1037 GLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQ-- 1094
L+V +D + ++ + +Y E +CGLCGNF+G +DL + + FGNSW+
Sbjct: 969 ALSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKVS 1028
Query: 1095 ---EETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRD 1151
+TR + P C + + +Q + C IL F++C+ +DP+ +
Sbjct: 1029 SQCADTRKVPLDSSPATC---HNNIMKQTMVDSSCRILT--SDVFQDCNKLVDPEPYLDV 1083
Query: 1152 CVYDRCLLP--GQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHS-------- 1201
C+YD C G CD +A YA C G V WR+ LCP SC +
Sbjct: 1084 CIYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVV-TWRTATLCPQSCEERNLRENGYEC 1142
Query: 1202 --HYEACSYGCPLSCGDLPVPGGCGSECHEGC--VCDEGFALSG--ESCLPLASCG-CVH 1254
Y +C+ C ++C P P C +C EGC C G L ++C+ C C
Sbjct: 1143 EWRYNSCAPACQVTC-QHPEPLACPVQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCEV 1201
Query: 1255 QGTYHPPGQ--TFYPG-PGCDSLCHCQEGGLVSCESSSCGPHEACQPSGG 1301
G G+ T P P +CHC L EACQ GG
Sbjct: 1202 AGRRFASGKKVTLNPSDPEHCQICHCDVVNLTC---------EACQEPGG 1242
Score = 157 bits (397), Expect = 7e-38
Identities = 125/475 (26%), Positives = 182/475 (38%), Gaps = 42/475 (8%)
Query: 925 CQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAV 984
C G +FDG + F G C+YLL G C + + F ++ + + + VS + +
Sbjct: 35 CSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRS----FSII--GDFQNGKRVSLSVYL 88
Query: 985 RVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDW 1044
G + G V D +P+ A+ G G + +G D
Sbjct: 89 -----GEFFDIHLFVNGTVTQGDQRVSMPY-ASKGLYLETEAGYYKLSGEAYGFVARIDG 142
Query: 1045 NARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEET-RPGCGA 1103
+ + Y CGLCGNFN DD + G ++ F NSW + C
Sbjct: 143 SGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQWCER 202
Query: 1104 TEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQS 1163
P S Q +C +L F CH +DP+ V C C G
Sbjct: 203 ASPPSSSCNISSGEMQKGLWEQCQLLKSTS-VFARCHPLVDPEPFVALCEKTLCECAGGL 261
Query: 1164 GPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPVPGGC 1223
C AL YA C G ++ W C CP Y C C +C L + C
Sbjct: 262 ECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQSLHINEMC 321
Query: 1224 GSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLV 1283
C +GC C EG L C+ C CVH G +PPG + C++ C C+ +
Sbjct: 322 QERCVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYPPGTSL--SRDCNT-CICRNSQWI 378
Query: 1284 SCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTC 1343
C + C P E C +G H+ +FD R F F G C Y+LA+ C
Sbjct: 379 -CSNEEC-PGE------------------CLVTGQSHFKSFDNRYFTFSGICQYLLARDC 418
Query: 1344 GTRPGLHRFAVLQENVAWGNGRVSV-TRVITVQVANFTLRLEQRQWKVTVRADGE 1397
H F+++ E V + R +V TR +TV++ L + + V DG+
Sbjct: 419 QD----HSFSIVIETVQCADDRDAVCTRSVTVRLPGLHNSLVKLKHGAGVAMDGQ 469
Score = 135 bits (340), Expect = 3e-31
Identities = 115/398 (28%), Positives = 169/398 (42%), Gaps = 43/398 (10%)
Query: 531 AVCRAQGDPHYTTFDGRRYDMMGTCSYTMVE-LCSEDDTLPAFSVEAKNEHRGSRRVSYV 589
A C G HY TFDG +Y G C Y +V+ C + F + N+ V
Sbjct: 865 ATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPG--TFRILVGNKGCSHPSVKCK 922
Query: 590 GLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVT 649
VT+ + L GEV + P+ E V +SG ++ L L V
Sbjct: 923 KRVTILVEGGEIELFDGEVNV--------KRPMK-DETHFEVVESGRYIILLLGKALSVV 973
Query: 650 YDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYL 709
+D +++ L +Q++VCGLCGN++G +D + + + D V+F +SWK+
Sbjct: 974 WDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKVSS---Q 1030
Query: 710 CEDGCQ---NNCPA-CTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDL 765
C D + ++ PA C + D C +LT F C+ +DP P+L+ C+YD
Sbjct: 1031 CADTRKVPLDSSPATCHNNIMKQTMVDSSCRILT--SDVFQDCNKLVDPEPYLDVCIYDT 1088
Query: 766 CVVG--GERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSCPANS----------RYE 813
C G+ C ++AYA C + G V WR+ CP SC + RY
Sbjct: 1089 CSCESIGDCACFCDTIAAYAHVCAQHG-KVVTWRTATLCPQSCEERNLRENGYECEWRYN 1147
Query: 814 LCGPACPTSCNGAAAPSNCSGRPCVEGC--VCLPGFVASG--GACVPASSCG-CTFQGLQ 868
C PAC +C P C + CVEGC C PG + CV C C G +
Sbjct: 1148 SCAPACQVTCQ-HPEPLACPVQ-CVEGCHAHCPPGKILDELLQTCVDPEDCPVCEVAGRR 1205
Query: 869 LAPGQEVWADELCQRRC-TCNGATHQVTCRDKQSCPAG 905
A G++V + C C+ +TC Q P G
Sbjct: 1206 FASGKKVTLNPSDPEHCQICHCDVVNLTCEACQE-PGG 1242
Score = 129 bits (324), Expect = 2e-29
Identities = 117/440 (26%), Positives = 176/440 (40%), Gaps = 42/440 (9%)
Query: 866 GLQLAPGQEVWA--DELCQRRCTCNGAT----HQVTCRD--KQSCPAGERCSVQNGLLGC 917
G + PG +VW D+ C +G T H+V C + SCP + GC
Sbjct: 1884 GNEKRPG-DVWTLPDQCHTVTCQPDGQTLLKSHRVNCDRGLRPSCPNSQSPVKVEETCGC 1942
Query: 918 YPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQT 977
C GS H V+FDG+ F G+C+Y+L + Q+ + +L
Sbjct: 1943 RWTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQDLEV----ILHNGACSPGAR 1998
Query: 978 VSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFG 1037
+++ V+ + V + + +V V+ L +P+ + +V V+ V G
Sbjct: 1999 QGCMKSIEVKHSALSVELHSDM--EVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLG 2056
Query: 1038 --LTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQE 1095
T T N P ++A GLCG + + A+D LR G + W
Sbjct: 2057 HIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTV 2116
Query: 1096 ETRPG--CGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCV 1153
+ RPG C C DS + C +L P F ECH L P C
Sbjct: 2117 Q-RPGQTCQPILEEQCLVPDS---------SHCQVLLLPL--FAECHKVLAPATFYAICQ 2164
Query: 1154 YDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLS 1213
D C +C+ +A+YA C+ G V WR+ + C +SCPP Y C +GCP
Sbjct: 2165 QDSC----HQEQVCEVIASYAHLCRTNGVCVD-WRTPDFCAMSCPPSLVYNHCEHGCPRH 2219
Query: 1214 C-GDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASC-GCV-HQGTYHPPGQTFYPGPG 1270
C G++ CG EGC C + SC+P +C C+ G H + + P
Sbjct: 2220 CDGNV---SSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPDHQ 2276
Query: 1271 CDSLCHCQEGGLVSCESSSC 1290
+C C G V+C + C
Sbjct: 2277 PCQICTCLSGRKVNCTTQPC 2296
Score = 120 bits (302), Expect = 7e-27
Identities = 115/425 (27%), Positives = 170/425 (40%), Gaps = 44/425 (10%)
Query: 494 GRTVLSPVEPSCE-GMQ--CAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYD 550
G+T+L +C+ G++ C Q V GC VC H TFDG+ +
Sbjct: 1908 GQTLLKSHRVNCDRGLRPSCPNSQSPVKVEETCGCRWTCPCVCTGSSTRHIVTFDGQNFK 1967
Query: 551 MMGTCSYTMVELCSEDDTLPAFSVEAKNEHRGS----RRVSYVGLVTVRAYSHSVSLTRG 606
+ G+CSY + + +D + H G+ R + + V+ + SV L
Sbjct: 1968 LTGSCSYVLFQNKEQDLEVIL--------HNGACSPGARQGCMKSIEVKHSALSVELHSD 2019
Query: 607 EVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVTY---DWDCQLALSLPAR 663
V V+ + +P + VY + V G + T+ + + QL LS P
Sbjct: 2020 ME--VTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLGHIFTFTPQNNEFQLQLS-PKT 2076
Query: 664 FQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTP 723
F + GLCG + + A+DF+ DG + D W + C+ + C
Sbjct: 2077 FASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQRPGQTCQPILEEQCLVPDS 2136
Query: 724 GQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYA 783
Q +L L FA CH L P F C D C + +C +++YA
Sbjct: 2137 SHCQV--------LLLPL---FAECHKVLAPATFYAICQQDSC----HQEQVCEVIASYA 2181
Query: 784 QACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVC 843
C G+ V DWR+P C +SCP + Y C CP C+G S+C P EGC C
Sbjct: 2182 HLCRTNGVCV-DWRTPDFCAMSCPPSLVYNHCEHGCPRHCDGNV--SSCGDHPS-EGCFC 2237
Query: 844 LPGFVASGGACVPASSC-GCTFQGLQLAPGQEVWA-DELCQRRCTCNGATHQVTCRDKQS 901
P V G+CVP +C C + E W D + CTC +V C Q
Sbjct: 2238 PPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPDHQPCQICTCLSG-RKVNC-TTQP 2295
Query: 902 CPAGE 906
CP +
Sbjct: 2296 CPTAK 2300
Score = 73.6 bits (179), Expect = 1e-12
Identities = 49/158 (31%), Positives = 68/158 (43%), Gaps = 26/158 (16%)
Query: 1227 CHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCE 1286
C GC+C G C+ L C C HQG + PG+T G C++ C C++
Sbjct: 804 CVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGETVKIG--CNT-CVCRD------R 854
Query: 1287 SSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQT-CGT 1345
+C H V +TC G HY TFDG ++ F G C YVL Q CG+
Sbjct: 855 KWNCTDH--------------VCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGS 900
Query: 1346 RPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRL 1383
PG F +L N + V + +T+ V + L
Sbjct: 901 NPG--TFRILVGNKGCSHPSVKCKKRVTILVEGGEIEL 936
Score = 40.8 bits (94), Expect = 0.010
Identities = 32/96 (33%), Positives = 37/96 (38%), Gaps = 25/96 (26%)
Query: 1254 HQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESS--------SCGPHEACQPSGGSLGC 1305
H T P GQT +C G SC +S +CG C C
Sbjct: 1900 HTVTCQPDGQTLLKS----HRVNCDRGLRPSCPNSQSPVKVEETCGCRWTCP-------C 1948
Query: 1306 VAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQ 1341
V GSST H TFDG+ F G+C YVL Q
Sbjct: 1949 VCTGSST------RHIVTFDGQNFKLTGSCSYVLFQ 1978
Score = 35.4 bits (80), Expect = 0.41
Identities = 34/121 (28%), Positives = 50/121 (41%), Gaps = 23/121 (19%)
Query: 1190 EELCPLSCPPHS-----HYEACS-YGCPLSCGDLPVP---GGCGSECHEGCVCDEGFALS 1240
+ + P SCPPH + C Y C +C + V G S C C +
Sbjct: 2368 KRVSPPSCPPHRLPTLRKTQCCDEYECACNCVNSTVSCPLGYLASTATNDCGC------T 2421
Query: 1241 GESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHC--QEGGLVSCESSSCGPHEACQP 1298
+CLP CVH+ T +P GQ + GCD +C C E ++ + C + C+
Sbjct: 2422 TTTCLP--DKVCVHRSTIYPVGQ--FWEEGCD-VCTCTDMEDAVMGLRVAQCS-QKPCED 2475
Query: 1299 S 1299
S
Sbjct: 2476 S 2476
Score = 32.7 bits (73), Expect = 2.7
Identities = 14/37 (37%), Positives = 18/37 (48%)
Query: 1310 SSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTR 1346
++ C G TFDG + F G C Y+LA C R
Sbjct: 32 TARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKR 68
Score = 31.2 bits (69), Expect = 7.7
Identities = 26/91 (28%), Positives = 34/91 (37%), Gaps = 21/91 (23%)
Query: 1212 LSCGDLPVPGGCGSECHEGCVCDEGFALS--GESCLPLASC----GCVHQGTYHPPGQTF 1265
+SC L VP VC GF LS +C P C C+ GT PG+T
Sbjct: 2547 VSCPQLEVP-----------VCPSGFQLSCKTSACCPSCRCERMEACMLNGTVIGPGKTV 2595
Query: 1266 YPGPGCDSLCHCQEGGL----VSCESSSCGP 1292
C Q G + + C ++C P
Sbjct: 2596 MIDVCTTCRCMVQVGVISGFKLECRKTTCNP 2626
>gi|161019170 mucin 5AC [Homo sapiens]
Length = 6207
Score = 308 bits (790), Expect = 2e-83
Identities = 261/954 (27%), Positives = 383/954 (40%), Gaps = 166/954 (17%)
Query: 527 AESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRGSRRV 586
A + VC GD HY TFDG + G C+Y E C F+V+ + GSR V
Sbjct: 727 AHNGRVCSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCRA--AYEDFNVQLRRGLVGSRPV 784
Query: 587 SYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGL 646
V V ++A + + G V L++ QR LP S + L V QSG +++ L
Sbjct: 785 --VTRVVIKAQGLVLEASNGSV---LINGQREELPYSRTG--LLVEQSGD--YIKVSIRL 835
Query: 647 VVTYDWDCQ--LALSLPARFQDQVCGLCGNYNGDPA-DDFLTPDGALAPDAVEFASSWKL 703
V+T+ W+ + L L ++ +Q CGLCG++NG PA ++F + L P ++F + KL
Sbjct: 836 VLTFLWNGEDSALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLTP--LQFGNLQKL 893
Query: 704 DDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVY 763
D C D CT + + +C T L FA CH +D +L C
Sbjct: 894 DGPTEQCPDPLPLPAGNCT-------DEEGICHR-TLLGPAFAECHALVDSTAYLAACAQ 945
Query: 764 DLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSC 823
DLC C Y++ C G +WR P CP +CP N +++ CG C +C
Sbjct: 946 DLCRCP---TCPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTC 1002
Query: 824 NGAAAPSNCSGRPCVEGCVCLPGFVAS------GGACVPASSCGCTFQGLQLAPGQEVWA 877
+ C CV+GC C PG + C+P C CT G +PG
Sbjct: 1003 SNPQRAQLCEDH-CVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHGGRTYSPGTSF-- 1059
Query: 878 DELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFD 937
+ C CTC+G Q C+D CP GTC G H ++D
Sbjct: 1060 NTTCSS-CTCSGGLWQ--CQDLP-CP-------------------GTCSVQGGAHISTYD 1096
Query: 938 GRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRG-SQTVSYTRAVRVEARGVKVAVR 996
+ +D G C+Y+L C ++ F VL E G + + +AV + G A+R
Sbjct: 1097 EKLYDLHGDCSYVLSKKCADSS----FTVLAELRKCGLTDNENCLKAVTLSLDGGDTAIR 1152
Query: 997 REYPGQVLVDDVLQYLPFQAADGQVQVFRQGRD-AVVRTDFGLTVTYDWNA--RVTAKVP 1053
+ G V ++ + LP AA+ + +F VV+T GL + +V ++
Sbjct: 1153 VQADGGVFLNSIYTQLPLSAAN--ITLFTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLD 1210
Query: 1054 SSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPKLD 1113
++ +CGLCGNFN + ADD G A AF N+W+ + C
Sbjct: 1211 PAHQGQMCGLCGNFNQNQADDFTALSGVVEATGAAFANTWKAQA--ACANARNSFEDPCS 1268
Query: 1114 SLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATY 1173
V + +++ C L DP F CHS ++P+ +C++D C LC AL++Y
Sbjct: 1269 LSVENENYARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNCERSEDCLCAALSSY 1328
Query: 1174 AAACQAAGATVHPWRSEELCP---LSCPPHSHYEACSYGCPLSC---GDLPVPGGCGSEC 1227
AC A G + WR + +C +CP Y C +C + V
Sbjct: 1329 VHACAAKGVQLSDWR-DGVCTKYMQNCPKSQRYAYVVDACQPTCRGLSEADVTCSVSFVP 1387
Query: 1228 HEGCVCDEG-FALSGESCLPLASCGCVHQGTYHPPGQTFY-------------------- 1266
+GC C G F +C+P C C GT PG+ +
Sbjct: 1388 VDGCTCPAGTFLNDAGACVPAQECPCYAHGTVLAPGEVVHDEGAVCSCTGGKLSCLGASL 1447
Query: 1267 ----------------------PGPGCDSLCHCQEGGLVSCESSSCGPHEACQP---SGG 1301
PG C CH + V C S+ C C P S G
Sbjct: 1448 QKSTGCAAPMVYLDCSNSSAGTPGAECLRSCHTLD---VGCFSTHCVSGCVCPPGLVSDG 1504
Query: 1302 SLGCVA--------------------VGSSTCQ------------------ASGDPHYTT 1323
S GC+A V +TC A GD H+ T
Sbjct: 1505 SGGCIAEEDCPCVHNEATYKPGETIRVDCNTCTCRNRRWECSHRLCLGTCVAYGDGHFIT 1564
Query: 1324 FDGRRFDFMGTCVYVLAQT-CGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQV 1376
FDG R+ F G+C Y+LAQ CG F ++ EN+ G + ++ I + V
Sbjct: 1565 FDGDRYSFEGSCEYILAQDYCGDNTTHGTFRIVTENIPCGTTGTTCSKAIKLFV 1618
Score = 251 bits (641), Expect = 4e-66
Identities = 250/966 (25%), Positives = 373/966 (38%), Gaps = 180/966 (18%)
Query: 516 CQVVGGKAGCV-AESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSV 574
C GG C C QG H +T+D + YD+ G CSY + + C++ +F+V
Sbjct: 1066 CTCSGGLWQCQDLPCPGTCSVQGGAHISTYDEKLYDLHGDCSYVLSKKCADS----SFTV 1121
Query: 575 EAKNEHRG-SRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQ 633
A+ G + + + VT+ ++ G V +++ ++LP+S + L
Sbjct: 1122 LAELRKCGLTDNENCLKAVTLSLDGGDTAIRVQADGGVFLNSIYTQLPLSAANITLFT-P 1180
Query: 634 SGPRAVVELVFGLVVTYDWD--CQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALA 691
S VV+ GL + Q+ + L Q Q+CGLCGN+N + ADDF G +
Sbjct: 1181 SSFFIVVQTGLGLQLLVQLVPLMQVFVRLDPAHQGQMCGLCGNFNQNQADDFTALSGVVE 1240
Query: 692 PDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQ--AQHYEGDRLCGMLTKLDGPFAVCH 749
FA++WK + ++ C + A+H+ C LT + F+ CH
Sbjct: 1241 ATGAAFANTWKAQAACANARNSFEDPCSLSVENENYARHW-----CSRLTDPNSAFSRCH 1295
Query: 750 DTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSP--ANCPLSCP 807
++P+PF C++D C LC LS+Y AC G+ + DWR +CP
Sbjct: 1296 SIINPKPFHSNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLSDWRDGVCTKYMQNCP 1355
Query: 808 ANSRYELCGPACPTSCNG-AAAPSNCS-GRPCVEGCVCLPG-FVASGGACVPASSCGCTF 864
+ RY AC +C G + A CS V+GC C G F+ GACVPA C C
Sbjct: 1356 KSQRYAYVVDACQPTCRGLSEADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQECPCYA 1415
Query: 865 QGLQLAPGQEVWADELCQRRCT-----CNGATHQ-----------VTCRDKQSCPAGERC 908
G LAPG EV DE CT C GA+ Q + C + + G C
Sbjct: 1416 HGTVLAPG-EVVHDEGAVCSCTGGKLSCLGASLQKSTGCAAPMVYLDCSNSSAGTPGAEC 1474
Query: 909 -------------------------SVQNGLLGCYPDRFGTCQGSG-----------DPH 932
V +G GC + C + D +
Sbjct: 1475 LRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKPGETIRVDCN 1534
Query: 933 YVSFDGRRFD-----FMGTCT--------------YLLVGS---------CGQNAALPAF 964
+ RR++ +GTC Y GS CG N F
Sbjct: 1535 TCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNTTHGTF 1594
Query: 965 RVLVENEHRGSQTVSYTRAVRV--------------------EARGVKVAVRREYPGQVL 1004
R++ EN G+ + ++A+++ R V R+ P
Sbjct: 1595 RIVTENIPCGTTGTTCSKAIKLFVEVRTAPAVSTPDPAANEPAPREASVGFRQRLPPLQS 1654
Query: 1005 VDDVLQYLPFQA------ADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAE 1058
+ +LQ F+A D ++ G V+ T G+ V++D V ++ Y
Sbjct: 1655 YELILQEGTFKAVARGPGGDPPYKIRYMGIFLVIET-HGMAVSWDRKTSVFIRLHQDYKG 1713
Query: 1059 ALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQ 1118
+CGLCGNF+ + +D A R +AL FGNSW + P C P D A
Sbjct: 1714 RVCGLCGNFDDNAINDFATRSRSVVGDALEFGNSW--KLSPSC----PDALAPKDPCTAN 1767
Query: 1119 QLQ---SKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLP--GQSGPLCDALATY 1173
+ ++ +C IL P F C S++D CV D C G C A+A Y
Sbjct: 1768 PFRKSWAQKQCSILHGP--TFAACRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAAY 1825
Query: 1174 AAACQAAGATVHPWRSEELCPLSCP---PHS----HYEACSYGCPLSCGD------LPVP 1220
A AC AG V WR+ + CPL C PH HY+ C C +C + + +P
Sbjct: 1826 AQACHDAGLCV-SWRTPDTCPLFCDFYNPHGGCEWHYQPCGAPCLKTCRNPSGHCLVDLP 1884
Query: 1221 GGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQ-GTYHPPGQTFYPGPGCDSLCHCQE 1279
G G C+ C + F + + +A CGC + G Y+ G C S C+C
Sbjct: 1885 GLEG--CYPKCPPSQPF-FNEDQMKCVAQCGCYDKDGNYYDVGARVPTAENCQS-CNCTP 1940
Query: 1280 GGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVL 1339
G+ S C + D Y T DG +G C+ +
Sbjct: 1941 SGIQCAHSLE--------------ACTCTYEDRTYSYQDVIYNTTDG-----LGACLIAI 1981
Query: 1340 AQTCGT 1345
+ GT
Sbjct: 1982 CGSNGT 1987
Score = 213 bits (542), Expect = 1e-54
Identities = 168/585 (28%), Positives = 253/585 (43%), Gaps = 61/585 (10%)
Query: 522 KAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHR 581
+A A + VC G HY TFDG + G C+Y E C F+++ +
Sbjct: 70 RASNPAHNGRVCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGA--AYEDFNIQLRRSQE 127
Query: 582 GSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVE 641
+ + V ++ + LT+G V LV+ LP S+ + + QS VE
Sbjct: 128 SAAPT--LSRVLMKVDGVVIQLTKGSV---LVNGHPVLLP--FSQSGVLIQQSSSYTKVE 180
Query: 642 LVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPA-DDFLTPDGALAPDAVEFASS 700
GLV+ ++ D L L L ++ ++ CGLCG++NG P + L+ + L P +EF +
Sbjct: 181 ARLGLVLMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTP--MEFGNL 238
Query: 701 WKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQ 760
K+DD C+D C+ G E L G L F+ C +D +LE
Sbjct: 239 QKMDDPTEQCQDPVPEPPRNCSTGFGICEE--LLHGQL------FSGCVALVDVGSYLEA 290
Query: 761 CVYDLCVVGGERL--SLCRGLSAYAQACLELGISVGDWRSPANCPLSCPANSRYELCGPA 818
C DLC L +C L+ Y++ C G DWR P CP CP N +Y C
Sbjct: 291 CRQDLCFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSP 350
Query: 819 CPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASG---GACVPASSCGCTFQGLQLAPGQEV 875
C +C+ C CV GC C G V CVP S C C + G APG
Sbjct: 351 CADTCSNQEHSRACEDH-CVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATY 409
Query: 876 WADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVS 935
D C CTC+G + +C++ CP GTC G H+ +
Sbjct: 410 STD--C-TNCTCSGG--RWSCQE-VPCP-------------------GTCSVLGGAHFST 444
Query: 936 FDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRG-SQTVSYTRAVRVEARGVKVA 994
FDG+++ G C+Y+L C + AF VL E G + + + ++V + G +
Sbjct: 445 FDGKQYTVHGDCSYVLTKPCDSS----AFTVLAELRRCGLTDSETCLKSVTLSLDGAQTV 500
Query: 995 VRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVV-RTDFGLTVTYDW--NARVTAK 1051
V + G+V ++ + LP AA+ V +FR ++ +T GL + ++ +
Sbjct: 501 VVIKASGEVFLNQIYTQLPISAAN--VTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQ 558
Query: 1052 VPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEE 1096
+ CGLCGNFN ADD G A A AF N+++ +
Sbjct: 559 LAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKTQ 603
Score = 155 bits (393), Expect = 2e-37
Identities = 132/479 (27%), Positives = 193/479 (40%), Gaps = 57/479 (11%)
Query: 925 CQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRV-LVENEHRGSQTVSYTRA 983
C G HY +FDG F F G C Y+ CG AA F + L ++ + T+S
Sbjct: 81 CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCG--AAYEDFNIQLRRSQESAAPTLS---R 135
Query: 984 VRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYD 1043
V ++ GV + + + G VLV+ LPF + +Q + V GL + ++
Sbjct: 136 VLMKVDGVVIQLTK---GSVLVNGHPVLLPFSQSGVLIQ--QSSSYTKVEARLGLVLMWN 190
Query: 1044 WNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGA 1103
+ + ++ + YA CGLCG+FNG P L + FGN Q+ P
Sbjct: 191 HDDSLLLELDTKYANKTCGLCGDFNGMPVVS-ELLSHNTKLTPMEFGNL-QKMDDPTEQC 248
Query: 1104 TEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQS 1163
+P P + + + G L F C + +D + C D C
Sbjct: 249 QDPVPEPPRNCSTGFGICEELLHGQL------FSGCVALVDVGSYLEACRQDLCFCEDTD 302
Query: 1164 --GPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPVPG 1221
+C LA Y+ C AG WR + CP CP + Y C C +C +
Sbjct: 303 LLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEHSR 362
Query: 1222 GCGSECHEGCVCDEGFALSG---ESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQ 1278
C C GC C EG L C+P++ C CV+ G + PG T+ C + C C
Sbjct: 363 ACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATY--STDCTN-CTC- 418
Query: 1279 EGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYV 1338
GG SC+ C TC G H++TFDG+++ G C YV
Sbjct: 419 SGGRWSCQEVPC-------------------PGTCSVLGGAHFSTFDGKQYTVHGDCSYV 459
Query: 1339 LAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVRADGE 1397
L + C + F VL E R +T T + + TL L+ Q V ++A GE
Sbjct: 460 LTKPCDS----SAFTVLAE-----LRRCGLTDSETC-LKSVTLSLDGAQTVVVIKASGE 508
Score = 145 bits (366), Expect = 3e-34
Identities = 179/676 (26%), Positives = 260/676 (38%), Gaps = 168/676 (24%)
Query: 406 AYVVKSV-PGCEGVALVVAQTKAISGLTIDGHAVGAKL----TWEAVPGSE---FSYAEV 457
AYVV + P C G++ T ++S + +DG A VP E +++ V
Sbjct: 1361 AYVVDACQPTCRGLSEADV-TCSVSFVPVDGCTCPAGTFLNDAGACVPAQECPCYAHGTV 1419
Query: 458 ELGTADMIHTAEATTN-----LGLLTFGLAKAIGYAT---------------AADCGRTV 497
L +++H A + L L L K+ G A A+C R+
Sbjct: 1420 -LAPGEVVHDEGAVCSCTGGKLSCLGASLQKSTGCAAPMVYLDCSNSSAGTPGAECLRSC 1478
Query: 498 LSPVEPSCEGMQCAAGQRCQ---VVGGKAGCVAE----------------------STAV 532
+ ++ C C +G C V G GC+AE +T
Sbjct: 1479 HT-LDVGCFSTHCVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKPGETIRVDCNTCT 1537
Query: 533 CR----------------AQGDPHYTTFDGRRYDMMGTCSYTMVE-LCSEDDTLPAFSVE 575
CR A GD H+ TFDG RY G+C Y + + C ++ T F +
Sbjct: 1538 CRNRRWECSHRLCLGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNTTHGTFRIV 1597
Query: 576 AKNEHRGSRRVS-------YVGLVTVRAYS------HSVSLTRGEVGFVLVDNQRSRLP- 621
+N G+ + +V + T A S + + VGF R RLP
Sbjct: 1598 TENIPCGTTGTTCSKAIKLFVEVRTAPAVSTPDPAANEPAPREASVGF------RQRLPP 1651
Query: 622 -----VSLSEGRLRVYQSGPRA-------------VVELVFGLVVTYDWDCQLALSLPAR 663
+ L EG + GP V+E G+ V++D + + L
Sbjct: 1652 LQSYELILQEGTFKAVARGPGGDPPYKIRYMGIFLVIE-THGMAVSWDRKTSVFIRLHQD 1710
Query: 664 FQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTP 723
++ +VCGLCGN++ + +DF T ++ DA+EF +SWKL C D P CT
Sbjct: 1711 YKGRVCGLCGNFDDNAINDFATRSRSVVGDALEFGNSWKLSPS---CPDALAPKDP-CTA 1766
Query: 724 GQAQHYEGDRLCGMLTKLDGP-FAVCHDTLDPRPFLEQCVYDLCVV--GGERLSLCRGLS 780
+ + C + L GP FA C +D + E CV D C GG+ C ++
Sbjct: 1767 NPFRKSWAQKQCSI---LHGPTFAACRSQVDSTKYYEACVNDACACDSGGDCECFCTAVA 1823
Query: 781 AYAQACLELGISVGDWRSPANCPLSCP-------ANSRYELCGPACPTSCNGAAAPSNC- 832
AYAQAC + G+ V WR+P CPL C Y+ CG C +C + +C
Sbjct: 1824 AYAQACHDAGLCV-SWRTPDTCPLFCDFYNPHGGCEWHYQPCGAPCLKTCRNPS--GHCL 1880
Query: 833 SGRPCVEGCV--CLPG---FVASGGACVPASSCGC-TFQGLQLAPGQEVWADELCQRRCT 886
P +EGC C P F CV + CGC G G V E CQ C
Sbjct: 1881 VDLPGLEGCYPKCPPSQPFFNEDQMKCV--AQCGCYDKDGNYYDVGARVPTAENCQ-SCN 1937
Query: 887 CNGATHQVTCRDKQSCPAGERCSVQNGLLGC-YPDRFGTCQGSGDPHYVSFDGRRFDFMG 945
C P+G +C+ C Y DR + Q D Y + DG +G
Sbjct: 1938 CT--------------PSGIQCAHSLEACTCTYEDRTYSYQ---DVIYNTTDG-----LG 1975
Query: 946 TCTYLLVGSCGQNAAL 961
C L+ CG N +
Sbjct: 1976 AC---LIAICGSNGTI 1988
Score = 122 bits (305), Expect = 3e-27
Identities = 123/438 (28%), Positives = 175/438 (39%), Gaps = 70/438 (15%)
Query: 497 VLSPVEPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCS 556
V P +P +C C+ VGG+ + +C G HY+TFDG Y G C+
Sbjct: 5380 VSDPSQPCDFHYEC----ECECVGGRG--ITPGAGICSMWGGSHYSTFDGTSYTFRGNCT 5433
Query: 557 YTM----------VELCSEDDTLPAFSVEAKNEHRGSRRVS--YVGLVTVRAYSHSVSLT 604
Y + + L ++ A + A R R +S Y + V +V++
Sbjct: 5434 YVLMREIHARFGNLSLYLDNHYCTASATAAAAAARCPRALSIHYKSMDIVL----TVTMV 5489
Query: 605 RG-EVGFVLVDNQRSRLPVS--LSEGRLRVYQSGPRAV-VEL-VFGLVVTYDWDCQLALS 659
G E G +L D ++PVS S+ + V G + V++ G+ VT++ A
Sbjct: 5490 HGKEEGLILFD----QIPVSSGFSKNGVLVSVLGTTTMRVDIPALGVSVTFNGQVFQARL 5545
Query: 660 LPARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGC----- 714
+ F + G CG + DD L DG A + A +W + D +DGC
Sbjct: 5546 PYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTWLVPDSR---KDGCWAPTG 5602
Query: 715 ----------QNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYD 764
++ P TP Q LC ++ L FA CH+ + P PF C+ D
Sbjct: 5603 TPPTASPAAPVSSTPTPTPCPPQ-----PLCDLM--LSQVFAECHNLVPPGPFFNACISD 5655
Query: 765 LCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPAN--CPLSCPANSRYELCGPACPTS 822
C G C+ L AYA+ C G+ DWR C L+CP Y+ CGP P +
Sbjct: 5656 HC--RGRLEVPCQSLEAYAELCRARGV-CSDWRGATGGLCDLTCPPTKVYKPCGPIQPAT 5712
Query: 823 CNGAAAPSNCSGRPCVEGCVCLPG---FVASGGACVPASSCGCTFQGLQLAPGQEVWADE 879
CN G EGC C F A G CV A C G PG E W
Sbjct: 5713 CNSRNQSPQLEG--MAEGCFCPEDQILFNAHMGICVQACPC-VGPDGFPKFPG-ERWVSN 5768
Query: 880 LCQRRCTCNGATHQVTCR 897
CQ C C+ + V C+
Sbjct: 5769 -CQ-SCVCDEGSVSVQCK 5784
Score = 97.8 bits (242), Expect = 7e-20
Identities = 127/503 (25%), Positives = 182/503 (36%), Gaps = 75/503 (14%)
Query: 841 CVCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQ-RRCTCNGAT-------- 891
C P V+S P+ + GC + L E W E C RC +
Sbjct: 5308 CPTSPPPVSSAPLSSPSPAPGCD-NAIPLRQVNETWTLENCTVARCVGDNRVVLLDPKPV 5366
Query: 892 HQVTCRDK----------QSCPAGERCSVQN-GLLGCYPDRFGTCQGSGDPHYVSFDGRR 940
VTC +K Q C C + G G P G C G HY +FDG
Sbjct: 5367 ANVTCVNKHLPIKVSDPSQPCDFHYECECECVGGRGITPGA-GICSMWGGSHYSTFDGTS 5425
Query: 941 FDFMGTCTYLLVGSCGQNAALPAFRVLVENEH------RGSQTVSYTRAVRVEARGVKVA 994
+ F G CTY+L+ +A + ++N + + RA+ + + + +
Sbjct: 5426 YTFRGNCTYVLMREI--HARFGNLSLYLDNHYCTASATAAAAAARCPRALSIHYKSMDIV 5483
Query: 995 -----VRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYD---WNA 1046
V + G +L D + F V V V G++VT++ + A
Sbjct: 5484 LTVTMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMRVDIPALGVSVTFNGQVFQA 5543
Query: 1047 RVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSW--QEETRPGCGAT 1104
R+ + + E CG C N + DD R G AA+ +W + + GC A
Sbjct: 5544 RLPYSLFHNNTEGQCGTCTN---NQRDDCLQRDGTTAASCKDMAKTWLVPDSRKDGCWA- 5599
Query: 1105 EPGDCPKLDSLVAQQLQSKNECGILADP------KGPFRECHSKLDPQGAVRDCVYDRCL 1158
P P S A + P F ECH+ + P C+ D C
Sbjct: 5600 -PTGTPPTASPAAPVSSTPTPTPCPPQPLCDLMLSQVFAECHNLVPPGPFFNACISDHC- 5657
Query: 1159 LPGQSGPLCDALATYAAACQAAGATVHPWRSEE--LCPLSCPPHSHYEACSYGCPLSC-- 1214
G+ C +L YA C+A G WR LC L+CPP Y+ C P +C
Sbjct: 5658 -RGRLEVPCQSLEAYAELCRARG-VCSDWRGATGGLCDLTCPPTKVYKPCGPIQPATCNS 5715
Query: 1215 -GDLPVPGGCGSECHEGCVCDEGFAL-SGESCLPLASCGCVHQGTYHPPGQTFYPG---- 1268
P G EGC C E L + + + +C CV P G +PG
Sbjct: 5716 RNQSPQLEGMA----EGCFCPEDQILFNAHMGICVQACPCV-----GPDGFPKFPGERWV 5766
Query: 1269 PGCDSLCHCQEGGL-VSCESSSC 1290
C S C C EG + V C+ C
Sbjct: 5767 SNCQS-CVCDEGSVSVQCKPLPC 5788
Score = 44.7 bits (104), Expect = 7e-04
Identities = 30/103 (29%), Positives = 42/103 (40%), Gaps = 22/103 (21%)
Query: 1246 PLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGC 1305
P+A+ CV++ H P + P CD C+ C+ GG
Sbjct: 5365 PVANVTCVNK---HLPIKVSDPSQPCDFHYECE-----------------CECVGGR--G 5402
Query: 1306 VAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPG 1348
+ G+ C G HY+TFDG + F G C YVL + R G
Sbjct: 5403 ITPGAGICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFG 5445
Score = 39.3 bits (90), Expect = 0.028
Identities = 30/87 (34%), Positives = 36/87 (41%), Gaps = 8/87 (9%)
Query: 1313 CQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVI 1372
C GD HY TFDG F F G C YV ++ C R A NV G V V+
Sbjct: 733 CSTWGDFHYKTFDGDVFRFPGLCNYVFSEHC-------RAAYEDFNVQLRRGLVGSRPVV 785
Query: 1373 T-VQVANFTLRLEQRQWKVTVRADGEQ 1398
T V + L LE V + E+
Sbjct: 786 TRVVIKAQGLVLEASNGSVLINGQREE 812
>gi|134031945 SCO-spondin [Homo sapiens]
Length = 5147
Score = 300 bits (767), Expect = 9e-81
Identities = 270/901 (29%), Positives = 363/901 (40%), Gaps = 138/901 (15%)
Query: 516 CQVVGGKAGCV-AESTAVCRAQGDPHYTTFDGRRYDMMGT--CSYTMVELCSEDDTLPAF 572
C G+ C A A C GD HY TFDGR Y G C Y++V+ + L
Sbjct: 546 CVCRDGRWHCAQALCPAECAVGGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVKGQLLILL 605
Query: 573 SVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVY 632
EH S + ++V + L + G VLV+ Q LP +EG L V
Sbjct: 606 ------EHGACDAGSCLHAISVSLEDTHIQLR--DSGAVLVNGQDVGLPWIGAEG-LSVR 656
Query: 633 QSGPRAVVELVFGLVVTYDWDCQLA-LSLPARFQDQVCGLCGNYNGDPADDFLTPDGALA 691
++ ++ G V + +A ++L R QV GLCG + + DDFLTP G +
Sbjct: 657 RASSAFLLLRWPGAQVLWGLSDPVAYITLDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVE 716
Query: 692 PDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDT 751
FAS +++ G C CT +H + C +L F CH
Sbjct: 717 TSIAAFASKFQVA-GKGRCPSEDSALLSPCTTHSQRHAFAEAACAILHS--SVFQECHRL 773
Query: 752 LDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSCPANSR 811
+D PF +C+ +C LC LSAYA+ C + G S WR+ CP+ CP
Sbjct: 774 VDKEPFYLRCLAAVCGCDPGSDCLCPVLSAYARRCAQEGASP-PWRNQTLCPVMCPGGQE 832
Query: 812 YELCGPACPTSCNGAAAPSNCSGR-PCVEGCVCLPGFVASG-GACVPASSCGCTFQGLQL 869
Y C PAC C P +C CV GC C G + G CVP S C C +
Sbjct: 833 YRECAPACGQHCG---KPEDCGELGSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRY 889
Query: 870 APGQEVWADE---LCQRR----CTCNGATHQVTCRDK------------------QSCPA 904
APG + +CQ R CT Q C + SCPA
Sbjct: 890 APGSATMKECNRCICQERGLWNCTARHCPSQAFCPRELVYAPGACLLTCDSPSANHSCPA 949
Query: 905 G---------------ERC-------------------SVQNGLLGCY----------PD 920
G ERC ++Q C
Sbjct: 950 GSTDGCVCPPGTVLLDERCVPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQR 1009
Query: 921 RFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSY 980
R G CQ SG PHYV+FDG F + G C YLLV A F V +N G+ ++
Sbjct: 1010 RSGRCQASGAPHYVTFDGLAFTYPGACEYLLV-----REASGLFTVSAQNLPCGASGLTC 1064
Query: 981 TRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQ-VQVFRQGRDAVVRTDFGLT 1039
T+A+ V G V + R G+ + + + P + G + + R G ++ T GLT
Sbjct: 1065 TKALAVRLEGTVVHMLR---GRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLT 1121
Query: 1040 VTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRP 1099
+ +D RV ++ + + GLCG+F+GD ++DL R G A +SW+ P
Sbjct: 1122 LLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWR--LSP 1179
Query: 1100 GCGATEPGDCPKLDSLVAQQL-QSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCL 1158
C EPGD P ++ + ++ CG L P F CH+++ PQ C+YD C
Sbjct: 1180 LC--PEPGDLPHPCTMNTHRAGWARARCGALLQPL--FTLCHAEVPPQQHYEWCLYDACG 1235
Query: 1159 LP--GQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGD 1216
G LC A+ATYA C G V WRS+ELC L C YEAC CP +C +
Sbjct: 1236 CDSGGDCECLCSAIATYADECARHGHHVR-WRSQELCSLQCEGGQVYEACGPTCPPTCHE 1294
Query: 1217 L-PVPG-GCG-SECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFY------- 1266
P PG C C EGC C EG L G +CL ASC C PPG
Sbjct: 1295 QHPEPGWHCQVVACVEGCFCPEGTLLHGGACLEPASCPCEWGRNSFPPGSVLQKDCGNCT 1354
Query: 1267 ----------PGPGCDSLC-HCQEGGLVSCESSSCGPH-------EACQPSGGSLGCVAV 1308
G C+ L C EG + E+ C PH + C GC A
Sbjct: 1355 CQEGQWHCGGDGGHCEELVPACAEGEALCQENGHCVPHGWLCDNQDDCGDGSDEEGCAAP 1414
Query: 1309 G 1309
G
Sbjct: 1415 G 1415
Score = 265 bits (677), Expect = 2e-70
Identities = 255/953 (26%), Positives = 363/953 (38%), Gaps = 178/953 (18%)
Query: 530 TAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRGSRRVSYV 589
+A C + HY TFDGR Y +G C+Y + + + + +RV+ +
Sbjct: 192 SATCASWSGFHYRTFDGRHYHFLGRCTYLLAGAADSTWAVHLTPGDRCPQPGHCQRVT-M 250
Query: 590 GLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVT 649
G V + +VS+ +G+ LV +S L LS L G V+ G+VV
Sbjct: 251 GPEEVLIQAGNVSV-KGQ----LVPEGQSWLLHGLSLQWL-----GDWLVLSGGLGVVVR 300
Query: 650 YDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYL 709
D +++S+ Q GLCG YNG P DDF+ P G LA A F +SW+L +
Sbjct: 301 LDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSESG 360
Query: 710 CEDGCQ--NNCPA-------CTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQ 760
C D + C PG + E +C L L+GPF CH + P + E
Sbjct: 361 CLDAVEVAQGCDPLGLIDADVEPGHLR-AEAQDVCHQL--LEGPFGQCHAQVSPAEYHEA 417
Query: 761 CVYDLCVVG-------GERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSCPANSRYE 813
C++ C G + ++C ++Y QAC I + WR P C CP Y
Sbjct: 418 CLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHI-RWRKPGFCERLCPGGQLYS 476
Query: 814 LCGPACPTSCN--GAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGCTFQGLQLAP 871
C CP SC G +C CV GC C G +G CVPA+ C C + + P
Sbjct: 477 DCVSLCPPSCEAVGQGEEESCR-EECVSGCECPRGLFWNGTLCVPAAHCPCYYCRQRYVP 535
Query: 872 GQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDP 931
G V R CN CRD + A C + C GD
Sbjct: 536 GDTV--------RQLCN----PCVCRDGRWHCAQALCPAE-------------CAVGGDG 570
Query: 932 HYVSFDGRRFDFMG--TCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAVRVEAR 989
HY++FDGR + F G C Y LV + ++L+ EH S A+ V
Sbjct: 571 HYLTFDGRSYSFWGGQGCRYSLVQDYVKG------QLLILLEHGACDAGSCLHAISVSLE 624
Query: 990 GVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVT 1049
+ +R G VLV+ LP+ A+G + V R ++ G V + + V
Sbjct: 625 DTHIQLRDS--GAVLVNGQDVGLPWIGAEG-LSVRRASSAFLLLRWPGAQVLWGLSDPVA 681
Query: 1050 -AKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGD 1108
+ +A + GLCG F + DD G + AF + +Q G
Sbjct: 682 YITLDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQ--------VAGKGR 733
Query: 1109 CPKLDSLVAQQLQSKNE--------CGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLP 1160
CP DS + + ++ C IL F+ECH +D + C+ C
Sbjct: 734 CPSEDSALLSPCTTHSQRHAFAEAACAIL--HSSVFQECHRLVDKEPFYLRCLAAVCGCD 791
Query: 1161 GQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPVP 1220
S LC L+ YA C GA+ PWR++ LCP+ CP Y C+ C CG P
Sbjct: 792 PGSDCLCPVLSAYARRCAQEGAS-PPWRNQTLCPVMCPGGQEYRECAPACGQHCGK---P 847
Query: 1221 GGCG--SECHEGCVCDEGFALSGE-SCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHC 1277
CG C GC C G E C+P + C C + PG C+ C C
Sbjct: 848 EDCGELGSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRYAPGSATM--KECNR-CIC 904
Query: 1278 QEGGLVSCESSSCGPHEACQ-----------------------PSGGSLGCVAVGSST-- 1312
QE GL +C + C C P+G + GCV +
Sbjct: 905 QERGLWNCTARHCPSQAFCPRELVYAPGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLL 964
Query: 1313 -----------CQASGD--------------------------------------PHYTT 1323
C+ SG PHY T
Sbjct: 965 DERCVPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVT 1024
Query: 1324 FDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQV 1376
FDG F + G C Y+L + GL F V +N+ G ++ T+ + V++
Sbjct: 1025 FDGLAFTYPGACEYLLVREAS---GL--FTVSAQNLPCGASGLTCTKALAVRL 1072
Score = 75.1 bits (183), Expect = 5e-13
Identities = 129/543 (23%), Positives = 175/543 (32%), Gaps = 127/543 (23%)
Query: 798 SPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSG-RPCVEGCVCLPGFVASGGACVP 856
+P C CPA C CP C+ C + C +GC C G + G CVP
Sbjct: 4054 NPMPCEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVP 4113
Query: 857 ASSCGCT-FQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLL 915
C CT QG APG + HQ C + CS Q G L
Sbjct: 4114 IGHCDCTDAQGHSWAPGSQ-----------------HQDACNN---------CSCQAGQL 4147
Query: 916 GCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGS 975
C T Q P + ++ + C++ SCG FR S
Sbjct: 4148 SC------TAQPCPPPTHCAWS--HWSAWSPCSH----SCGPRGQQSRFR--------SS 4187
Query: 976 QTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTD 1035
+ S+ R E + + P L + L G+ Q + V+ D
Sbjct: 4188 TSGSWAPECREEQSQSQPCPQPSCPPLCLQGTRSRTLGDSWLQGECQRCSCTPEGVICED 4247
Query: 1036 FGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGG---QAANALAFGNS 1092
V W + SS+++ CG G+ A R ++ L
Sbjct: 4248 TECAVPEAWT------LWSSWSDCPVS-CGG--GNQVRTRACRAAAPHHRSPPCLGPDTQ 4298
Query: 1093 WQEETRPG----------------CG---ATEPGDCPKLDSLVAQQLQSKNECGILADPK 1133
+++ PG CG A+ G CP L+A+ + N + D +
Sbjct: 4299 TRQQPCPGLLEACSWGPWGPCSRSCGPGLASRSGSCP---CLMAKADPTCNSTFLHLDTQ 4355
Query: 1134 GPFRECHSKLDPQGAVRDCVYD------RC---LLPGQ----SGPLCDALATYAAACQAA 1180
G C+S P+ +CV+ RC +L Q GP A A C
Sbjct: 4356 G----CYSGPCPE----ECVWSSWSSWTRCSCRVLVQQRYRHQGPASRG-ARAGAPCTRL 4406
Query: 1181 GATVHPWRSEELCPLSCPPHSHYEACSYGCP------LS---CGDLPVPGGCGSECHEGC 1231
P SC P + AC C LS C DLP C GC
Sbjct: 4407 DGHFRPCLISNCSEDSCTPPFEFHACGSPCAGLCATHLSHQLCQDLP-------PCQPGC 4459
Query: 1232 VCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGP----GCDSLCHCQEGGLVSCES 1287
C +G C+P C C H G T PG GC C C+ G L C S
Sbjct: 4460 YCPKGLLEQAGGCIPPEECNCWHTSA-AGAGMTLAPGDRLQLGCKE-CECRRGEL-HCTS 4516
Query: 1288 SSC 1290
C
Sbjct: 4517 QGC 4519
Score = 74.7 bits (182), Expect = 6e-13
Identities = 40/122 (32%), Positives = 50/122 (40%), Gaps = 14/122 (11%)
Query: 1194 PLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCV 1253
P CP + C+ G P SC +L P G CH GC C G L C+P C C
Sbjct: 3087 PGMCPRDKQWLDCAQG-PASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCA 3145
Query: 1254 HQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCG----------PHEACQPSGGSL 1303
H+G +PPG T C++ C C G + +C S C P C S G
Sbjct: 3146 HEGHLYPPGSTVV--RPCEN-CSCVSGLIANCSSWPCAEGEPTWSPWTPWSQCSASCGPA 3202
Query: 1304 GC 1305
C
Sbjct: 3203 RC 3204
Score = 61.2 bits (147), Expect = 7e-09
Identities = 45/123 (36%), Positives = 50/123 (40%), Gaps = 18/123 (14%)
Query: 815 CGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGCTFQGL----QLA 870
C CP SC C PC GC C PG + G CVP SSC C +LA
Sbjct: 4678 CANQCPHSCADLWDRVQCLQGPCRPGCRCPPGQLVQDGRCVPISSCRCGLPSANASWELA 4737
Query: 871 PGQEVWADELCQRRCTCNGATHQVTCRDKQSCP------AGERCSVQNGLLGCYPDRFGT 924
P Q V D CQ CTC + C Q CP A CS G G +R T
Sbjct: 4738 PAQAVQLD--CQ-NCTC--VNESLVC-PHQECPVLGPWSAWSSCSAPCG--GGTMERHRT 4789
Query: 925 CQG 927
C+G
Sbjct: 4790 CEG 4792
Score = 59.3 bits (142), Expect = 3e-08
Identities = 44/141 (31%), Positives = 51/141 (36%), Gaps = 30/141 (21%)
Query: 1181 GATVHPWRSEELCPLSCPPHSHYEACSYG----------------CPLSCGDLPVPGGCG 1224
G P S+E P P S C G CP SC D C
Sbjct: 2590 GGAPCPGASQERAPCGLQPCSGGTDCELGRVYVSADLCQKGLVPPCPPSCLDPKANRSCS 2649
Query: 1225 SECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVS 1284
C EGC C G L CLPL+ C C+ PG +F G C S C C++G L+
Sbjct: 2650 GHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLG-NC-SQCVCEKGELL- 2706
Query: 1285 CESSSCGPHEACQPSGGSLGC 1305
CQP G L C
Sbjct: 2707 -----------CQPGGCPLPC 2716
Score = 58.2 bits (139), Expect = 6e-08
Identities = 73/259 (28%), Positives = 89/259 (34%), Gaps = 63/259 (24%)
Query: 1082 QAANALAFGNSWQEETRPGCGATEPGD-CPKLDSLVAQQLQSKNECGILADPK-----GP 1135
Q+ +A + +SW E PG T P D C + ++ Q Q +C DP GP
Sbjct: 3600 QSRSAGSRFSSW-ESLEPGEVVTGPCDNCTCVAGIL--QCQEVPDC---PDPGVWSSWGP 3653
Query: 1136 FRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPL 1195
+ +C +R RC P GP + C+ AG
Sbjct: 3654 WEDCSVSCGGGEQLRS---RRCARPPCPGPARQSRTCSTQVCREAG-------------- 3696
Query: 1196 SCPPHSHYEACS--YGCPLSCGDLPVPGGCGSE-CHEGCVCDEGFALSGESCLPLASCGC 1252
CP Y C GCP SC + GC SE C EGC C EG +C + C C
Sbjct: 3697 -CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLAC--VQECPC 3753
Query: 1253 VHQ--------GTYHPPGQTFYPGPGCDS---------LCHCQEGGLVSCESSSC----- 1290
V T PGQ PG DS C C G L SC C
Sbjct: 3754 VLTAWLLQELGATIGDPGQPLGPGDELDSGQTLRTSCGNCSCAHGKL-SCSLDDCFEADG 3812
Query: 1291 -----GPHEACQPSGGSLG 1304
P C S G LG
Sbjct: 3813 GFGPWSPWGPCSRSCGGLG 3831
Score = 56.2 bits (134), Expect = 2e-07
Identities = 34/107 (31%), Positives = 43/107 (40%), Gaps = 7/107 (6%)
Query: 1193 CPLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSE--CHEGCVCDEGFALSGESCLPLASC 1250
C CP C+ CP C DL C + C +GC C +G C+P+ C
Sbjct: 4058 CEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGHC 4117
Query: 1251 GCVH-QGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEAC 1296
C QG PG C++ C CQ G L SC + C P C
Sbjct: 4118 DCTDAQGHSWAPGSQHQ--DACNN-CSCQAGQL-SCTAQPCPPPTHC 4160
Score = 54.7 bits (130), Expect = 7e-07
Identities = 38/128 (29%), Positives = 48/128 (37%), Gaps = 17/128 (13%)
Query: 802 CPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCG 861
CP CP C +CP C + C PC GC C G + G CVP ++C
Sbjct: 4815 CP-ECPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTACP 4873
Query: 862 CTFQGL-------------QLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERC 908
CT L +L PG + + C RC C+G + D Q P
Sbjct: 4874 CTQHSLPWGLTLTLEEQAQELPPGTVLTRN--C-TRCVCHGGAFSCSLVDCQVPPGETWQ 4930
Query: 909 SVQNGLLG 916
V G LG
Sbjct: 4931 QVAPGELG 4938
Score = 52.8 bits (125), Expect = 2e-06
Identities = 35/118 (29%), Positives = 44/118 (37%), Gaps = 18/118 (15%)
Query: 802 CPLSCPANSRY---ELC---GPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACV 855
C CP N + E C G CP C C+G C GC C PG +C+
Sbjct: 2882 CTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPGIECTGF-CAPGCTCPPGLFLHNASCL 2940
Query: 856 PASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNG 913
P S C C G +++A R +CN TC + ERC V G
Sbjct: 2941 PRSQCPCQLHG-------QLYASGAMARLDSCNNC----TCVSGKMACTSERCPVACG 2987
Score = 52.4 bits (124), Expect = 3e-06
Identities = 64/241 (26%), Positives = 85/241 (35%), Gaps = 35/241 (14%)
Query: 1101 CGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLP 1160
CG +L A QL +N + P +EC L P A + C P
Sbjct: 4725 CGLPSANASWELAPAQAVQLDCQNCTCVNESLVCPHQEC-PVLGPWSA-----WSSCSAP 4778
Query: 1161 GQSGPL-----CDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCG 1215
G + C+ A CQA + + CP CPP AC+ CP C
Sbjct: 4779 CGGGTMERHRTCEG-GPGVAPCQAQDTEQRQECNLQPCP-ECPPGQVLSACATSCPCLCW 4836
Query: 1216 DLPVPGGCGSE-CHEGCVCDEGFALSGESCLPLASCGCVHQG-------TYHPPGQTFYP 1267
L C E C GC C G L +C+P +C C T Q P
Sbjct: 4837 HLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTACPCTQHSLPWGLTLTLEEQAQELPP 4896
Query: 1268 GP----GCDSLCHCQEGGLVSCESSSC--GPHEACQP-SGGSLG-----CVAVGSSTCQA 1315
G C + C C GG SC C P E Q + G LG C+ + ++ Q+
Sbjct: 4897 GTVLTRNC-TRCVC-HGGAFSCSLVDCQVPPGETWQQVAPGELGLCEQTCLEMNATKTQS 4954
Query: 1316 S 1316
+
Sbjct: 4955 N 4955
Score = 52.0 bits (123), Expect = 4e-06
Identities = 42/140 (30%), Positives = 48/140 (34%), Gaps = 27/140 (19%)
Query: 1155 DRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSC 1214
D C P G +C AL C A + Y C CP SC
Sbjct: 3289 DYCEGPRAQGEVCQALPCPVTNCTAIEG------------------AEYSPCGPPCPRSC 3330
Query: 1215 GDLPVPGGCGSECHEGCVCDEGFALS--GESCLPLASCGCVH--QGTYHPPGQTFYPGPG 1270
DL C C GC C G LS G C+ C C+ G H PG G
Sbjct: 3331 DDLV---HCVWRCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDG 3387
Query: 1271 CDSLCHCQEGGLVSCESSSC 1290
C+ C C EG L +C C
Sbjct: 3388 CNH-CTCLEGRL-NCTDLPC 3405
Score = 50.8 bits (120), Expect = 9e-06
Identities = 46/170 (27%), Positives = 67/170 (39%), Gaps = 21/170 (12%)
Query: 1192 LCPLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCV--CDEGFALSGESCL---- 1245
LCP+ PP + + C PG G+ C E EG + C
Sbjct: 73 LCPIYKPPETRPAKWNRTVRTCC-----PGWGGAHCTEALAKASPEGHCFAMWQCQLQAG 127
Query: 1246 -PLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLG 1304
AS G + + P GQ+++ G + C L SS QP G++G
Sbjct: 128 SANASAGSLEECCARPWGQSWWDGSS-QACRSCSSRHLPGSASSPA----LLQPLAGAVG 182
Query: 1305 CV----AVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLH 1350
+ S+TC + HY TFDGR + F+G C Y+LA + +H
Sbjct: 183 QLWSQHQRPSATCASWSGFHYRTFDGRHYHFLGRCTYLLAGAADSTWAVH 232
Score = 50.8 bits (120), Expect = 9e-06
Identities = 38/116 (32%), Positives = 46/116 (39%), Gaps = 17/116 (14%)
Query: 776 CRGLSAYAQACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGR 835
C G A + C L V NC + + Y CGP CP SC+ +C R
Sbjct: 3291 CEGPRAQGEVCQALPCPV------TNC--TAIEGAEYSPCGPPCPRSCDDLV---HCVWR 3339
Query: 836 PCVEGCVCLPGFVAS--GGACVPASSCGC--TFQGLQLAPGQEVWADELCQRRCTC 887
C GC C PG V S G CV C C G + PG + + C CTC
Sbjct: 3340 -CQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGC-NHCTC 3393
Score = 49.7 bits (117), Expect = 2e-05
Identities = 22/46 (47%), Positives = 25/46 (54%), Gaps = 1/46 (2%)
Query: 817 PACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGC 862
P CP SC A +CSG CVEGC C PG + C+P S C C
Sbjct: 2633 PPCPPSCLDPKANRSCSGH-CVEGCRCPPGLLLHDTRCLPLSECPC 2677
Score = 47.4 bits (111), Expect = 1e-04
Identities = 38/144 (26%), Positives = 52/144 (36%), Gaps = 19/144 (13%)
Query: 803 PLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGC 862
P CP + ++ C P SC +AP + + C GC C G + CVP C C
Sbjct: 3087 PGMCPRDKQWLDCAQG-PASCAELSAPRG-TNQTCHPGCHCPSGMLLLNNVCVPTQDCPC 3144
Query: 863 TFQGLQLAPGQEVWADELCQRRC-TCNGATHQVTCRDKQSCPAGE----------RCSVQ 911
+G PG V R C C+ + + C GE +CS
Sbjct: 3145 AHEGHLYPPGSTV------VRPCENCSCVSGLIANCSSWPCAEGEPTWSPWTPWSQCSAS 3198
Query: 912 NGLLGCYPDRFGTCQGSGDPHYVS 935
G C+ RF S P V+
Sbjct: 3199 CGPARCHRHRFCARSPSAVPSTVA 3222
Score = 47.0 bits (110), Expect = 1e-04
Identities = 60/230 (26%), Positives = 82/230 (35%), Gaps = 37/230 (16%)
Query: 701 WKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPF--- 757
W L G ++ CQ C C GQ H + C P C T P+
Sbjct: 4836 WHLQPGAICVQEPCQPGC-GCPGGQLLH---NGTCV-------PPTACPCTQHSLPWGLT 4884
Query: 758 --LEQCVYDL----CVVGGERLSLCRGLSAYAQACLELGISVGD-WRSPANCPLSCPANS 810
LE+ +L + +C G A++ + ++ + G+ W+ A L
Sbjct: 4885 LTLEEQAQELPPGTVLTRNCTRCVCHG-GAFSCSLVDCQVPPGETWQQVAPGELG----- 4938
Query: 811 RYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPG-FVASGGACVPASSCGCTFQGLQL 869
LC C N SNCS GCVC PG F + G CVP C C G
Sbjct: 4939 ---LCEQTC-LEMNATKTQSNCSSARA-SGCVCQPGHFRSQAGPCVPEDHCECWHLGRPH 4993
Query: 870 APGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYP 919
PG E W E C+ +G +C GE ++ G C P
Sbjct: 4994 LPGSE-W-QEACESCLCLSGRPVCTQHCSPLTCAQGEEMVLEPG--SCCP 5039
Score = 45.4 bits (106), Expect = 4e-04
Identities = 34/98 (34%), Positives = 43/98 (43%), Gaps = 12/98 (12%)
Query: 802 CP-LSCPANSRYELCGPACPTSCNGAAAPSNCSGR-PCVE-GCVCLPGFV-ASGGACVPA 857
CP +C ++ C P CP +C+ + C PC GC C G V S G CV
Sbjct: 1807 CPNATCSGELMFQPCAP-CPLTCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSEGWCVWP 1865
Query: 858 SSCGCTFQGLQLAPGQEVWAD-ELC------QRRCTCN 888
C C G + PGQ + AD +LC RRC N
Sbjct: 1866 RQCPCLVDGARYWPGQRIKADCQLCICQDGRPRRCRLN 1903
Score = 45.1 bits (105), Expect = 5e-04
Identities = 32/106 (30%), Positives = 40/106 (37%), Gaps = 15/106 (14%)
Query: 806 CPANSRYELCGPA--CPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSC--- 860
CPA Y C P CP SC C C EGC C G ACV C
Sbjct: 3697 CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLACVQECPCVLT 3756
Query: 861 -------GCTF--QGLQLAPGQEVWADELCQRRC-TCNGATHQVTC 896
G T G L PG E+ + + + C C+ A +++C
Sbjct: 3757 AWLLQELGATIGDPGQPLGPGDELDSGQTLRTSCGNCSCAHGKLSC 3802
Score = 43.1 bits (100), Expect = 0.002
Identities = 33/133 (24%), Positives = 46/133 (34%), Gaps = 10/133 (7%)
Query: 1164 GPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSY------GCPLSCGDL 1217
G C +LA C + ++ C CP + + + CP C
Sbjct: 2854 GRSCSSLAPGDTTCPGPHSQTRDCNTQP-CTAQCPENMLFRSAEQCHQEGGPCPRLCLTQ 2912
Query: 1218 PVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHC 1277
C C GC C G L SCLP + C C G + G C++ C C
Sbjct: 2913 GPGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYASG-AMARLDSCNN-CTC 2970
Query: 1278 QEGGLVSCESSSC 1290
G + +C S C
Sbjct: 2971 VSGKM-ACTSERC 2982
Score = 42.7 bits (99), Expect = 0.003
Identities = 29/105 (27%), Positives = 37/105 (35%), Gaps = 14/105 (13%)
Query: 775 LCRGLSAYAQACLELGISVGDWRSPANCPLS------------CPANSRYELCGPACPTS 822
+C G S ++AC G P N S C CG CP S
Sbjct: 3486 MCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTDCGGGQSLHPCGQPCPRS 3545
Query: 823 CNGAAAPSNCSGRP--CVEGCVCLPGFVASGGACVPASSCGCTFQ 865
C + S C C C C G ++ G CVP + C C +Q
Sbjct: 3546 CQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRCQYQ 3590
Score = 42.0 bits (97), Expect = 0.004
Identities = 25/84 (29%), Positives = 31/84 (36%), Gaps = 6/84 (7%)
Query: 1175 AACQAAGATVHPWRSEELCPLSCPPHSHYEA-----CSYGCPLSCGDLPVPGGC-GSECH 1228
A G PW E CP + C+ CP SC DL C C
Sbjct: 4642 AEALCGGGCREPWAQESCNGGPCPECEAQDTVFTLDCANQCPHSCADLWDRVQCLQGPCR 4701
Query: 1229 EGCVCDEGFALSGESCLPLASCGC 1252
GC C G + C+P++SC C
Sbjct: 4702 PGCRCPPGQLVQDGRCVPISSCRC 4725
Score = 41.6 bits (96), Expect = 0.006
Identities = 73/320 (22%), Positives = 95/320 (29%), Gaps = 94/320 (29%)
Query: 1079 GGGQAANALAFGNSWQEETRPG---CGATEPGDCPKLDSLVAQQLQSKNECGILADPKGP 1135
GGG S E + G C PG CP+ D Q C L+ P+G
Sbjct: 3057 GGGYRNRTRGSSRSLMEFSTCGLQPCAGPVPGMCPR-DKQWLDCAQGPASCAELSAPRGT 3115
Query: 1136 FRECHSKLD-PQGAVR-----------DCVYDRCLLPGQSGPL-----CDALATYAAACQ 1178
+ CH P G + C ++ L P S + C ++ A C
Sbjct: 3116 NQTCHPGCHCPSGMLLLNNVCVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCS 3175
Query: 1179 A-----AGATVHPWRSEELCPLSCPP-----HSHYEACSYGCPLSCGDLPVP-------- 1220
+ T PW C SC P H P + LP+P
Sbjct: 3176 SWPCAEGEPTWSPWTPWSQCSASCGPARCHRHRFCARSPSAVPSTVAPLPLPATPTPLCS 3235
Query: 1221 -----------------GGCG-----SECHEGC---------VCD-----------EGFA 1238
GG G S C C CD EG
Sbjct: 3236 GPEAEEEPCLLQGCDRAGGWGPWGPWSHCSRSCGGGLRSRTRACDQPPPQGLGDYCEGPR 3295
Query: 1239 LSGESC----LPLASCGCVHQGTYHPPGQTFYPGP-GCDSLCHCQEGGLVSCESSSCGPH 1293
GE C P+ +C + Y P G P P CD L HC + C+ P
Sbjct: 3296 AQGEVCQALPCPVTNCTAIEGAEYSPCGP---PCPRSCDDLVHC----VWRCQPGCYCPP 3348
Query: 1294 EACQPSGGSLGCVAVGSSTC 1313
S G++ CV G +C
Sbjct: 3349 GQVLSSNGAI-CVQPGHCSC 3367
Score = 40.4 bits (93), Expect = 0.013
Identities = 53/203 (26%), Positives = 66/203 (32%), Gaps = 50/203 (24%)
Query: 1132 PKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEE 1191
P GP+ C L R C R P + G C T + CQ +
Sbjct: 3477 PWGPWSPCDMCLGQSHRSRAC--SRPPTP-EGGRPCPGNHTQSRPCQ---------ENST 3524
Query: 1192 LCPLSCPPHSHYEACSYGCPLSCGDLPV-----PGGCGSECHEGCVCDEGFALSGESCLP 1246
C C C CP SC DL PG G C C C G C+P
Sbjct: 3525 QCT-DCGGGQSLHPCGQPCPRSCQDLSPGSVCQPGSVG--CQPTCGCPLGQLSQDGLCVP 3581
Query: 1247 LASCGCVHQ--------------GTYHPPGQTFYPGP----GCDSLCHCQEGGLVSCES- 1287
A C C +Q G+ ++ PG CD+ C C G++ C+
Sbjct: 3582 PAHCRCQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDN-CTC-VAGILQCQEV 3639
Query: 1288 ---------SSCGPHEACQPSGG 1301
SS GP E C S G
Sbjct: 3640 PDCPDPGVWSSWGPWEDCSVSCG 3662
Score = 38.9 bits (89), Expect = 0.037
Identities = 29/101 (28%), Positives = 33/101 (32%), Gaps = 15/101 (14%)
Query: 1206 CSYGCPLSCGDLPVPGGCGSECHEGCVCDEG-FALSGESCLPLASCGCVHQGTYHPPGQT 1264
C C L C S GCVC G F C+P C C H G H PG
Sbjct: 4940 CEQTC-LEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDHCECWHLGRPHLPGSE 4998
Query: 1265 FYPG----------PGCDSLCH---CQEGGLVSCESSSCGP 1292
+ P C C C +G + E SC P
Sbjct: 4999 WQEACESCLCLSGRPVCTQHCSPLTCAQGEEMVLEPGSCCP 5039
Score = 32.3 bits (72), Expect = 3.5
Identities = 30/99 (30%), Positives = 37/99 (37%), Gaps = 13/99 (13%)
Query: 1218 PVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHC 1277
P P G G +C G C GC HQG H G+ ++ GP C +C C
Sbjct: 1940 PRPSGRGRQCR-------GIHRKARRCQTEPCEGCEHQGQVHRVGERWHGGP-C-RVCQC 1990
Query: 1278 QEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQAS 1316
C S C P +C P G L G S C +
Sbjct: 1991 LHNLTAHC-SPYC-PLGSC-PQGWVL-VEGTGESCCHCA 2025
Score = 31.2 bits (69), Expect = 7.7
Identities = 34/129 (26%), Positives = 46/129 (35%), Gaps = 33/129 (25%)
Query: 796 WRSPANCPLSCPANS--RYELCGPACP----TSCNGAAAPSNCSGRPC---VEGC----- 841
W S ++CP+SC + R C A P C G + +PC +E C
Sbjct: 4259 WSSWSDCPVSCGGGNQVRTRACRAAAPHHRSPPCLG--PDTQTRQQPCPGLLEACSWGPW 4316
Query: 842 -----VCLPGFVASGGAC-----VPASSCGCTF-----QGLQLAPGQE--VWADELCQRR 884
C PG + G+C +C TF QG P E VW+ R
Sbjct: 4317 GPCSRSCGPGLASRSGSCPCLMAKADPTCNSTFLHLDTQGCYSGPCPEECVWSSWSSWTR 4376
Query: 885 CTCNGATHQ 893
C+C Q
Sbjct: 4377 CSCRVLVQQ 4385
>gi|239755545 PREDICTED: otogelin isoform 1 [Homo sapiens]
Length = 2852
Score = 280 bits (716), Expect = 7e-75
Identities = 247/825 (29%), Positives = 336/825 (40%), Gaps = 105/825 (12%)
Query: 511 AAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLP 570
A G RCQ+V E ++CRA G H TFDG Y + G SYT+V +
Sbjct: 60 ATGPRCQMVYNAG---PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQ-- 114
Query: 571 AFSVEAKNE-------HRGSRRVS--YVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLP 621
+FS++ N+ + SR VS +VG + + +T G R +LP
Sbjct: 115 SFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHL---AKEVTHG--------GMRVQLP 163
Query: 622 VSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPAD 681
+ RL+ Q +V + +D + + + GLCGN N DP D
Sbjct: 164 HVMGSARLQ--QLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKD 221
Query: 682 DFLTPDGALAPDAVEFASSWKLDDGDY--------LCEDGCQNNCPACTPGQAQHYEGDR 733
D +T G L D VEF SW+ + L C P G + E
Sbjct: 222 DLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEA-- 279
Query: 734 LCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISV 793
L PF CH + P PF C DLC G+ + CR L+ YA+AC + G +
Sbjct: 280 ------LLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 333
Query: 794 GDWRSP-ANCPLSCPANS-RYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASG 851
WR+ C + C + Y C CP SC+ A+ + S CV+GC C G +
Sbjct: 334 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVD-SEIACVDGCYCPNGLIFED 392
Query: 852 GACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQ 911
G CV + C C F G PG V D C CTC + + CPA CSV
Sbjct: 393 GGCVAPAECPCEFHGTLYPPGSVVKED--C-NTCTCTSGKWECS---TAVCPA--ECSV- 443
Query: 912 NGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENE 971
+GD H+ +FDGRR+ F TC Y+L S F V ++N
Sbjct: 444 ----------------TGDIHFTTFDGRRYTFPATCQYILAKSRSSG----TFTVTLQNA 483
Query: 972 HRG-SQTVSYTRAVRVEA-RGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRD 1029
G +Q + ++V V + + V G VL+ D + +P D ++ R
Sbjct: 484 PCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIP-PYTDDAFEIRRLSSV 542
Query: 1030 AV-VRTDFGLTVTYDWNA-RVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANAL 1087
+ VRT+ G+ V YD R+ +V + E GLCG FNG+ DD G +
Sbjct: 543 FLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQ 602
Query: 1088 AFGNSWQEETRPGCGATEPGD-CPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQ 1146
FGNSW +T C G D + S C +L F C + L P
Sbjct: 603 LFGNSW--KTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEM--FAPCSAFLSPV 658
Query: 1147 GAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEAC 1206
C D C GQ LC LA YA C+ G V C LSC Y C
Sbjct: 659 PYFEQCRRDACRC-GQP-CLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPC 716
Query: 1207 SYGCPLSCGDLPVPGGCG---------SECHEGCVC--DEGFALSGESCLPLASCGCVHQ 1255
C +C DL P CG EC EGC C D + C+P C C Q
Sbjct: 717 VAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQ 776
Query: 1256 GTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSG 1300
G +PPG + P G CHC++ G++SC+S + P AC P+G
Sbjct: 777 GVDYPPGDSDIPSLG---HCHCKD-GVMSCDSRA--PAAAC-PAG 814
Score = 162 bits (409), Expect = 3e-39
Identities = 130/461 (28%), Positives = 184/461 (39%), Gaps = 49/461 (10%)
Query: 892 HQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLL 951
H C ++ G RC + + P+R C+ G H +FDG + G +Y L
Sbjct: 49 HPAFCDCRRFNATGPRCQM---VYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTL 105
Query: 952 VGSCGQNAALPAFRVLVENEHR-GSQTVSYTRAVR---VEARGVKVAVRREYPG-QVLVD 1006
VG +F + V N+ + GS + +RAV V + + +A + G +V +
Sbjct: 106 VGRHEPEGQ--SFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLP 163
Query: 1007 DVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGN 1066
V+ Q G V +VR T+ +D + V K+ GLCGN
Sbjct: 164 HVMGSARLQQLAGYV---------IVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGN 214
Query: 1067 FNGDPADDLALRGGGQAANALAFGNSWQEETR---PGCGATEPGDCPKLDSLVAQQLQSK 1123
N DP DDL G + + F +SWQE+ PG + P L
Sbjct: 215 NNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVY 274
Query: 1124 NECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGAT 1183
+C L P PF CH+ + P C D C G C ALA YA AC AG
Sbjct: 275 EQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRP 332
Query: 1184 VHPWRSE-ELCPLSCPPHSH-YEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSG 1241
+ WR++ C + C + Y C CP SC C +GC C G
Sbjct: 333 LQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFED 392
Query: 1242 ESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGG 1301
C+ A C C GT +PPG C++ C C G C ++ C
Sbjct: 393 GGCVAPAECPCEFHGTLYPPGSVVKED--CNT-CTCTSGKW-ECSTAVC----------- 437
Query: 1302 SLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQT 1342
+ C +GD H+TTFDGRR+ F TC Y+LA++
Sbjct: 438 --------PAECSVTGDIHFTTFDGRRYTFPATCQYILAKS 470
Score = 115 bits (287), Expect = 4e-25
Identities = 111/421 (26%), Positives = 162/421 (38%), Gaps = 61/421 (14%)
Query: 790 GISVGDWRSPANCPLSCPANSRYELCGP-------ACPTSCNGAAAPSNCSGR-PCVEGC 841
G+ D R+PA +CPA + C + +C + S R PC+ GC
Sbjct: 798 GVMSCDSRAPA---AACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGC 854
Query: 842 VCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQS 901
C G + G AC C CT++G + PG +V + C C C + Q T S
Sbjct: 855 ACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSP--C-HTCVCQRGSFQCTLHPCAS 911
Query: 902 CPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL 961
TC GD HY +FDG FDF+G C LV S
Sbjct: 912 ----------------------TCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD---- 945
Query: 962 PAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADG-- 1019
+F V+VEN + S + + + + + V DD P D
Sbjct: 946 VSFSVIVENVNCYSSGMICRKFISINVGNSLI---------VFDDDSGNPSPESFLDDKQ 996
Query: 1020 QVQVFRQGRDAVVR-TDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALR 1078
+V +R G +V +T+ +D V + + L GLCGNF+ +++
Sbjct: 997 EVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTP 1056
Query: 1079 GGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRE 1138
+ N FG+SW P +P D L+ L ++ +K EC IL F
Sbjct: 1057 ENLELTNPQEFGSSWAAVECP--DTLDPRDMCVLNPL--REPFAKKECSILLSE--VFEI 1110
Query: 1139 CHSKLDPQGAVRDCVYDR--CLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLS 1196
CH +D +C+ D C G C +++ YA C G V WR+ LCP
Sbjct: 1111 CHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYD 1169
Query: 1197 C 1197
C
Sbjct: 1170 C 1170
Score = 98.6 bits (244), Expect = 4e-20
Identities = 82/297 (27%), Positives = 126/297 (42%), Gaps = 27/297 (9%)
Query: 516 CQVVGGKAGCVAESTA-VCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSV 574
C G C A C A GD HY TFDG +D +G C +V+ S+ +FSV
Sbjct: 895 CVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD----VSFSV 950
Query: 575 EAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQS 634
+N + Y + R + +S+ G V D+ + P S + + V+
Sbjct: 951 IVENVN------CYSSGMICRKF---ISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTW 1001
Query: 635 GPRAVVELVFGLV-VTYDWDCQLALSLPA--RFQDQVCGLCGNYNGDPADDFLTPDGALA 691
+ F +T WD + + + A ++Q Q+ GLCGN++ ++ TP+
Sbjct: 1002 RVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLEL 1061
Query: 692 PDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDT 751
+ EF SSW + C D C + + C +L L F +CH
Sbjct: 1062 TNPQEFGSSWAAVE----CPDTLDPR-DMCVLNPLREPFAKKECSIL--LSEVFEICHPV 1114
Query: 752 LDPRPFLEQCVYDL--CVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSC 806
+D F C+ D C GG+ C +SAYA C + G++V DWR+P CP C
Sbjct: 1115 VDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1170
Score = 91.3 bits (225), Expect = 6e-18
Identities = 115/456 (25%), Positives = 171/456 (37%), Gaps = 78/456 (17%)
Query: 480 GLAKAIGYATAADCGRTVLSPVEPSCEGMQCAAGQ-----------------RCQV---- 518
GLA+A+ T A+ T + E C C GQ RC +
Sbjct: 1962 GLAEALATTTEANTSTTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLA 2021
Query: 519 --VGGKAGC-VAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVE 575
VGG C + E C D + TFDG + Y + + S D+ L ++
Sbjct: 2022 VRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQ--SPDEMLTVHVLD 2079
Query: 576 AKNEHRGSRRVSYVGLVTVRA--YSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQ 633
K+ + G LV + +H V++ R V VD Q PVS R+
Sbjct: 2080 CKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRK-VTVDLQPVWPPVS--RYGFRIED 2136
Query: 634 SGPRAVVELVFGLVVTYDWDCQLALSLPARFQD-QVCGLCGNYNGDPADDFLTPDGAL-- 690
+G ++ + + + L + ++ Q GLCG +GD A+D DG++
Sbjct: 2137 TGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVG 2196
Query: 691 -APDAVEFASSWKLDDG------DYLCEDGCQN-NCPACTPGQAQHYEGDRLCGMLTKLD 742
A D F SW++ D C +C C R+ T
Sbjct: 2197 GAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCL----------RMVSNRT--- 2243
Query: 743 GPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANC 802
F+ CH + P F E + D V C L+ Y C + + + +WR C
Sbjct: 2244 --FSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCI-EWRRSDYC 2296
Query: 803 PLSCPANSRYELCGPAC--PTSCN----GAAAPSNCSGRPCVEGCVCLPGFV---ASGGA 853
P C ++S Y+ C AC P +C G P +C + EGCVC G +
Sbjct: 2297 PFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHC--QVLGEGCVCSEGTILHRRHSAL 2354
Query: 854 CVPASSCGCT-FQGLQLAPGQEVWADEL---CQRRC 885
C+P + C CT G+ A G E W L CQ +C
Sbjct: 2355 CIPEAKCACTDSMGVPRALG-ETWNSSLSGCCQHQC 2389
Score = 78.6 bits (192), Expect = 4e-14
Identities = 119/493 (24%), Positives = 165/493 (33%), Gaps = 111/493 (22%)
Query: 877 ADELCQRRCTCNGATHQVTCRDKQSCPAGE---RCSVQNGLLG---------CYPDRFGT 924
A++ C R G +V Q CP G RC G+LG C P
Sbjct: 1983 AEQDCVRHICLEGQLIRVN--QSQHCPQGAAPPRC----GILGLAVRVGGDRCCPLWECA 2036
Query: 925 CQGS--GDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL----------------PAFRV 966
C+ S D +V+FDG Y+L S + + P V
Sbjct: 2037 CRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLV 2096
Query: 967 LVENEHRGSQTV--SYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVF 1024
++ H Q + R V V+ + V V R G + D Y+ +D Q+Q
Sbjct: 2097 MLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRY--GFRIEDTGHMYMILTPSDIQIQWL 2154
Query: 1025 RQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGG---G 1081
+V +K + LCG+C +GD A+DL L+ G G
Sbjct: 2155 HSSGLMIVEA---------------SKTSKAQGHGLCGIC---DGDAANDLTLKDGSVVG 2196
Query: 1082 QAANALAFGNSWQEE---TRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRE 1138
A + F +SWQ T G P C D ++ S F
Sbjct: 2197 GAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRT----------FSA 2246
Query: 1139 CHSKLDPQGA----VRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCP 1194
CH + P+ +RD Y + C AL Y A C + WR + CP
Sbjct: 2247 CHRFVPPESFCELWIRDTKYVQ--------QPCVALTVYVAMCHKFHVCIE-WRRSDYCP 2297
Query: 1195 LSCPPHSHYEACSYGC--PLSCGDLPVPGGCGSECH---EGCVCDEGFAL---SGESCLP 1246
C S Y+AC C P +C D + C EGCVC EG L C+P
Sbjct: 2298 FLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIP 2357
Query: 1247 LASCGCV-HQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGC 1305
A C C G G+T+ L C C + P LGC
Sbjct: 2358 EAKCACTDSMGVPRALGETW-------------NSSLSGCCQHQCQAPDTIVPV--DLGC 2402
Query: 1306 VAVGSSTCQASGD 1318
+ +C G+
Sbjct: 2403 PSPRPESCLRFGE 2415
Score = 68.9 bits (167), Expect = 3e-11
Identities = 47/156 (30%), Positives = 66/156 (42%), Gaps = 35/156 (22%)
Query: 1227 CHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCH---CQEGGLV 1283
C GC C +G G++C C C +G + ++PG S CH CQ G
Sbjct: 850 CLSGCACPQGLLRHGDACFLPEECPCTWKG------KEYFPGDQVMSPCHTCVCQRGSF- 902
Query: 1284 SCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTC-VYVLAQT 1342
C C +STC A GD HY TFDG FDF+G C V+++ T
Sbjct: 903 QCTLHPC-------------------ASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKST 943
Query: 1343 CGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVAN 1378
F+V+ ENV + + + I++ V N
Sbjct: 944 SDV-----SFSVIVENVNCYSSGMICRKFISINVGN 974
Score = 32.7 bits (73), Expect = 2.7
Identities = 22/77 (28%), Positives = 30/77 (38%), Gaps = 11/77 (14%)
Query: 1277 CQEGGLVSCESSSCGPHEACQPSGGSLG---------CVAVGSSTCQAS--GDPHYTTFD 1325
C EG L+ S P A P G LG C + C+ S D + TFD
Sbjct: 1992 CLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFD 2051
Query: 1326 GRRFDFMGTCVYVLAQT 1342
G +Y+L+Q+
Sbjct: 2052 GSHVALFKEAIYILSQS 2068
>gi|239755543 PREDICTED: otogelin isoform 2 [Homo sapiens]
Length = 2924
Score = 280 bits (716), Expect = 7e-75
Identities = 247/825 (29%), Positives = 336/825 (40%), Gaps = 105/825 (12%)
Query: 511 AAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLP 570
A G RCQ+V E ++CRA G H TFDG Y + G SYT+V +
Sbjct: 132 ATGPRCQMVYNAG---PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQ-- 186
Query: 571 AFSVEAKNE-------HRGSRRVS--YVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLP 621
+FS++ N+ + SR VS +VG + + +T G R +LP
Sbjct: 187 SFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHL---AKEVTHG--------GMRVQLP 235
Query: 622 VSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPAD 681
+ RL+ Q +V + +D + + + GLCGN N DP D
Sbjct: 236 HVMGSARLQ--QLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKD 293
Query: 682 DFLTPDGALAPDAVEFASSWKLDDGDY--------LCEDGCQNNCPACTPGQAQHYEGDR 733
D +T G L D VEF SW+ + L C P G + E
Sbjct: 294 DLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEA-- 351
Query: 734 LCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISV 793
L PF CH + P PF C DLC G+ + CR L+ YA+AC + G +
Sbjct: 352 ------LLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 405
Query: 794 GDWRSP-ANCPLSCPANS-RYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASG 851
WR+ C + C + Y C CP SC+ A+ + S CV+GC C G +
Sbjct: 406 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVD-SEIACVDGCYCPNGLIFED 464
Query: 852 GACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQ 911
G CV + C C F G PG V D C CTC + + CPA CSV
Sbjct: 465 GGCVAPAECPCEFHGTLYPPGSVVKED--C-NTCTCTSGKWECS---TAVCPA--ECSV- 515
Query: 912 NGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENE 971
+GD H+ +FDGRR+ F TC Y+L S F V ++N
Sbjct: 516 ----------------TGDIHFTTFDGRRYTFPATCQYILAKSRSSG----TFTVTLQNA 555
Query: 972 HRG-SQTVSYTRAVRVEA-RGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRD 1029
G +Q + ++V V + + V G VL+ D + +P D ++ R
Sbjct: 556 PCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIP-PYTDDAFEIRRLSSV 614
Query: 1030 AV-VRTDFGLTVTYDWNA-RVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANAL 1087
+ VRT+ G+ V YD R+ +V + E GLCG FNG+ DD G +
Sbjct: 615 FLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQ 674
Query: 1088 AFGNSWQEETRPGCGATEPGD-CPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQ 1146
FGNSW +T C G D + S C +L F C + L P
Sbjct: 675 LFGNSW--KTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEM--FAPCSAFLSPV 730
Query: 1147 GAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEAC 1206
C D C GQ LC LA YA C+ G V C LSC Y C
Sbjct: 731 PYFEQCRRDACRC-GQP-CLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPC 788
Query: 1207 SYGCPLSCGDLPVPGGCG---------SECHEGCVC--DEGFALSGESCLPLASCGCVHQ 1255
C +C DL P CG EC EGC C D + C+P C C Q
Sbjct: 789 VAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQ 848
Query: 1256 GTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSG 1300
G +PPG + P G CHC++ G++SC+S + P AC P+G
Sbjct: 849 GVDYPPGDSDIPSLG---HCHCKD-GVMSCDSRA--PAAAC-PAG 886
Score = 162 bits (409), Expect = 3e-39
Identities = 130/461 (28%), Positives = 184/461 (39%), Gaps = 49/461 (10%)
Query: 892 HQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLL 951
H C ++ G RC + + P+R C+ G H +FDG + G +Y L
Sbjct: 121 HPAFCDCRRFNATGPRCQM---VYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTL 177
Query: 952 VGSCGQNAALPAFRVLVENEHR-GSQTVSYTRAVR---VEARGVKVAVRREYPG-QVLVD 1006
VG +F + V N+ + GS + +RAV V + + +A + G +V +
Sbjct: 178 VGRHEPEGQ--SFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLP 235
Query: 1007 DVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGN 1066
V+ Q G V +VR T+ +D + V K+ GLCGN
Sbjct: 236 HVMGSARLQQLAGYV---------IVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGN 286
Query: 1067 FNGDPADDLALRGGGQAANALAFGNSWQEETR---PGCGATEPGDCPKLDSLVAQQLQSK 1123
N DP DDL G + + F +SWQE+ PG + P L
Sbjct: 287 NNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVY 346
Query: 1124 NECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGAT 1183
+C L P PF CH+ + P C D C G C ALA YA AC AG
Sbjct: 347 EQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRP 404
Query: 1184 VHPWRSE-ELCPLSCPPHSH-YEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSG 1241
+ WR++ C + C + Y C CP SC C +GC C G
Sbjct: 405 LQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFED 464
Query: 1242 ESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGG 1301
C+ A C C GT +PPG C++ C C G C ++ C
Sbjct: 465 GGCVAPAECPCEFHGTLYPPGSVVKED--CNT-CTCTSGKW-ECSTAVC----------- 509
Query: 1302 SLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQT 1342
+ C +GD H+TTFDGRR+ F TC Y+LA++
Sbjct: 510 --------PAECSVTGDIHFTTFDGRRYTFPATCQYILAKS 542
Score = 115 bits (287), Expect = 4e-25
Identities = 111/421 (26%), Positives = 162/421 (38%), Gaps = 61/421 (14%)
Query: 790 GISVGDWRSPANCPLSCPANSRYELCGP-------ACPTSCNGAAAPSNCSGR-PCVEGC 841
G+ D R+PA +CPA + C + +C + S R PC+ GC
Sbjct: 870 GVMSCDSRAPA---AACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGC 926
Query: 842 VCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQS 901
C G + G AC C CT++G + PG +V + C C C + Q T S
Sbjct: 927 ACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSP--C-HTCVCQRGSFQCTLHPCAS 983
Query: 902 CPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL 961
TC GD HY +FDG FDF+G C LV S
Sbjct: 984 ----------------------TCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD---- 1017
Query: 962 PAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADG-- 1019
+F V+VEN + S + + + + + V DD P D
Sbjct: 1018 VSFSVIVENVNCYSSGMICRKFISINVGNSLI---------VFDDDSGNPSPESFLDDKQ 1068
Query: 1020 QVQVFRQGRDAVVR-TDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALR 1078
+V +R G +V +T+ +D V + + L GLCGNF+ +++
Sbjct: 1069 EVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTP 1128
Query: 1079 GGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRE 1138
+ N FG+SW P +P D L+ L ++ +K EC IL F
Sbjct: 1129 ENLELTNPQEFGSSWAAVECP--DTLDPRDMCVLNPL--REPFAKKECSILLSE--VFEI 1182
Query: 1139 CHSKLDPQGAVRDCVYDR--CLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLS 1196
CH +D +C+ D C G C +++ YA C G V WR+ LCP
Sbjct: 1183 CHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYD 1241
Query: 1197 C 1197
C
Sbjct: 1242 C 1242
Score = 98.6 bits (244), Expect = 4e-20
Identities = 82/297 (27%), Positives = 126/297 (42%), Gaps = 27/297 (9%)
Query: 516 CQVVGGKAGCVAESTA-VCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSV 574
C G C A C A GD HY TFDG +D +G C +V+ S+ +FSV
Sbjct: 967 CVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD----VSFSV 1022
Query: 575 EAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQS 634
+N + Y + R + +S+ G V D+ + P S + + V+
Sbjct: 1023 IVENVN------CYSSGMICRKF---ISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTW 1073
Query: 635 GPRAVVELVFGLV-VTYDWDCQLALSLPA--RFQDQVCGLCGNYNGDPADDFLTPDGALA 691
+ F +T WD + + + A ++Q Q+ GLCGN++ ++ TP+
Sbjct: 1074 RVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLEL 1133
Query: 692 PDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDT 751
+ EF SSW + C D C + + C +L L F +CH
Sbjct: 1134 TNPQEFGSSWAAVE----CPDTLDPR-DMCVLNPLREPFAKKECSIL--LSEVFEICHPV 1186
Query: 752 LDPRPFLEQCVYDL--CVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSC 806
+D F C+ D C GG+ C +SAYA C + G++V DWR+P CP C
Sbjct: 1187 VDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1242
Score = 91.3 bits (225), Expect = 6e-18
Identities = 115/456 (25%), Positives = 171/456 (37%), Gaps = 78/456 (17%)
Query: 480 GLAKAIGYATAADCGRTVLSPVEPSCEGMQCAAGQ-----------------RCQV---- 518
GLA+A+ T A+ T + E C C GQ RC +
Sbjct: 2034 GLAEALATTTEANTSTTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLA 2093
Query: 519 --VGGKAGC-VAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVE 575
VGG C + E C D + TFDG + Y + + S D+ L ++
Sbjct: 2094 VRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQ--SPDEMLTVHVLD 2151
Query: 576 AKNEHRGSRRVSYVGLVTVRA--YSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQ 633
K+ + G LV + +H V++ R V VD Q PVS R+
Sbjct: 2152 CKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRK-VTVDLQPVWPPVS--RYGFRIED 2208
Query: 634 SGPRAVVELVFGLVVTYDWDCQLALSLPARFQD-QVCGLCGNYNGDPADDFLTPDGAL-- 690
+G ++ + + + L + ++ Q GLCG +GD A+D DG++
Sbjct: 2209 TGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVG 2268
Query: 691 -APDAVEFASSWKLDDG------DYLCEDGCQN-NCPACTPGQAQHYEGDRLCGMLTKLD 742
A D F SW++ D C +C C R+ T
Sbjct: 2269 GAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCL----------RMVSNRT--- 2315
Query: 743 GPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANC 802
F+ CH + P F E + D V C L+ Y C + + + +WR C
Sbjct: 2316 --FSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCI-EWRRSDYC 2368
Query: 803 PLSCPANSRYELCGPAC--PTSCN----GAAAPSNCSGRPCVEGCVCLPGFV---ASGGA 853
P C ++S Y+ C AC P +C G P +C + EGCVC G +
Sbjct: 2369 PFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHC--QVLGEGCVCSEGTILHRRHSAL 2426
Query: 854 CVPASSCGCT-FQGLQLAPGQEVWADEL---CQRRC 885
C+P + C CT G+ A G E W L CQ +C
Sbjct: 2427 CIPEAKCACTDSMGVPRALG-ETWNSSLSGCCQHQC 2461
Score = 78.6 bits (192), Expect = 4e-14
Identities = 119/493 (24%), Positives = 165/493 (33%), Gaps = 111/493 (22%)
Query: 877 ADELCQRRCTCNGATHQVTCRDKQSCPAGE---RCSVQNGLLG---------CYPDRFGT 924
A++ C R G +V Q CP G RC G+LG C P
Sbjct: 2055 AEQDCVRHICLEGQLIRVN--QSQHCPQGAAPPRC----GILGLAVRVGGDRCCPLWECA 2108
Query: 925 CQGS--GDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL----------------PAFRV 966
C+ S D +V+FDG Y+L S + + P V
Sbjct: 2109 CRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLV 2168
Query: 967 LVENEHRGSQTV--SYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVF 1024
++ H Q + R V V+ + V V R G + D Y+ +D Q+Q
Sbjct: 2169 MLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRY--GFRIEDTGHMYMILTPSDIQIQWL 2226
Query: 1025 RQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGG---G 1081
+V +K + LCG+C +GD A+DL L+ G G
Sbjct: 2227 HSSGLMIVEA---------------SKTSKAQGHGLCGIC---DGDAANDLTLKDGSVVG 2268
Query: 1082 QAANALAFGNSWQEE---TRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRE 1138
A + F +SWQ T G P C D ++ S F
Sbjct: 2269 GAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRT----------FSA 2318
Query: 1139 CHSKLDPQGA----VRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCP 1194
CH + P+ +RD Y + C AL Y A C + WR + CP
Sbjct: 2319 CHRFVPPESFCELWIRDTKYVQ--------QPCVALTVYVAMCHKFHVCIE-WRRSDYCP 2369
Query: 1195 LSCPPHSHYEACSYGC--PLSCGDLPVPGGCGSECH---EGCVCDEGFAL---SGESCLP 1246
C S Y+AC C P +C D + C EGCVC EG L C+P
Sbjct: 2370 FLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIP 2429
Query: 1247 LASCGCV-HQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGC 1305
A C C G G+T+ L C C + P LGC
Sbjct: 2430 EAKCACTDSMGVPRALGETW-------------NSSLSGCCQHQCQAPDTIVPV--DLGC 2474
Query: 1306 VAVGSSTCQASGD 1318
+ +C G+
Sbjct: 2475 PSPRPESCLRFGE 2487
Score = 68.9 bits (167), Expect = 3e-11
Identities = 47/156 (30%), Positives = 66/156 (42%), Gaps = 35/156 (22%)
Query: 1227 CHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCH---CQEGGLV 1283
C GC C +G G++C C C +G + ++PG S CH CQ G
Sbjct: 922 CLSGCACPQGLLRHGDACFLPEECPCTWKG------KEYFPGDQVMSPCHTCVCQRGSF- 974
Query: 1284 SCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTC-VYVLAQT 1342
C C +STC A GD HY TFDG FDF+G C V+++ T
Sbjct: 975 QCTLHPC-------------------ASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKST 1015
Query: 1343 CGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVAN 1378
F+V+ ENV + + + I++ V N
Sbjct: 1016 SDV-----SFSVIVENVNCYSSGMICRKFISINVGN 1046
Score = 32.7 bits (73), Expect = 2.7
Identities = 22/77 (28%), Positives = 30/77 (38%), Gaps = 11/77 (14%)
Query: 1277 CQEGGLVSCESSSCGPHEACQPSGGSLG---------CVAVGSSTCQAS--GDPHYTTFD 1325
C EG L+ S P A P G LG C + C+ S D + TFD
Sbjct: 2064 CLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFD 2123
Query: 1326 GRRFDFMGTCVYVLAQT 1342
G +Y+L+Q+
Sbjct: 2124 GSHVALFKEAIYILSQS 2140
>gi|239749989 PREDICTED: otogelin isoform 2 [Homo sapiens]
Length = 2852
Score = 280 bits (716), Expect = 7e-75
Identities = 247/825 (29%), Positives = 336/825 (40%), Gaps = 105/825 (12%)
Query: 511 AAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLP 570
A G RCQ+V E ++CRA G H TFDG Y + G SYT+V +
Sbjct: 60 ATGPRCQMVYNAG---PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQ-- 114
Query: 571 AFSVEAKNE-------HRGSRRVS--YVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLP 621
+FS++ N+ + SR VS +VG + + +T G R +LP
Sbjct: 115 SFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHL---AKEVTHG--------GMRVQLP 163
Query: 622 VSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPAD 681
+ RL+ Q +V + +D + + + GLCGN N DP D
Sbjct: 164 HVMGSARLQ--QLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKD 221
Query: 682 DFLTPDGALAPDAVEFASSWKLDDGDY--------LCEDGCQNNCPACTPGQAQHYEGDR 733
D +T G L D VEF SW+ + L C P G + E
Sbjct: 222 DLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEA-- 279
Query: 734 LCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISV 793
L PF CH + P PF C DLC G+ + CR L+ YA+AC + G +
Sbjct: 280 ------LLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 333
Query: 794 GDWRSP-ANCPLSCPANS-RYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASG 851
WR+ C + C + Y C CP SC+ A+ + S CV+GC C G +
Sbjct: 334 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVD-SEIACVDGCYCPNGLIFED 392
Query: 852 GACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQ 911
G CV + C C F G PG V D C CTC + + CPA CSV
Sbjct: 393 GGCVAPAECPCEFHGTLYPPGSVVKED--C-NTCTCTSGKWECS---TAVCPA--ECSV- 443
Query: 912 NGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENE 971
+GD H+ +FDGRR+ F TC Y+L S F V ++N
Sbjct: 444 ----------------TGDIHFTTFDGRRYTFPATCQYILAKSRSSG----TFTVTLQNA 483
Query: 972 HRG-SQTVSYTRAVRVEA-RGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRD 1029
G +Q + ++V V + + V G VL+ D + +P D ++ R
Sbjct: 484 PCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIP-PYTDDAFEIRRLSSV 542
Query: 1030 AV-VRTDFGLTVTYDWNA-RVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANAL 1087
+ VRT+ G+ V YD R+ +V + E GLCG FNG+ DD G +
Sbjct: 543 FLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQ 602
Query: 1088 AFGNSWQEETRPGCGATEPGD-CPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQ 1146
FGNSW +T C G D + S C +L F C + L P
Sbjct: 603 LFGNSW--KTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEM--FAPCSAFLSPV 658
Query: 1147 GAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEAC 1206
C D C GQ LC LA YA C+ G V C LSC Y C
Sbjct: 659 PYFEQCRRDACRC-GQP-CLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPC 716
Query: 1207 SYGCPLSCGDLPVPGGCG---------SECHEGCVC--DEGFALSGESCLPLASCGCVHQ 1255
C +C DL P CG EC EGC C D + C+P C C Q
Sbjct: 717 VAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQ 776
Query: 1256 GTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSG 1300
G +PPG + P G CHC++ G++SC+S + P AC P+G
Sbjct: 777 GVDYPPGDSDIPSLG---HCHCKD-GVMSCDSRA--PAAAC-PAG 814
Score = 162 bits (409), Expect = 3e-39
Identities = 130/461 (28%), Positives = 184/461 (39%), Gaps = 49/461 (10%)
Query: 892 HQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLL 951
H C ++ G RC + + P+R C+ G H +FDG + G +Y L
Sbjct: 49 HPAFCDCRRFNATGPRCQM---VYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTL 105
Query: 952 VGSCGQNAALPAFRVLVENEHR-GSQTVSYTRAVR---VEARGVKVAVRREYPG-QVLVD 1006
VG +F + V N+ + GS + +RAV V + + +A + G +V +
Sbjct: 106 VGRHEPEGQ--SFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLP 163
Query: 1007 DVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGN 1066
V+ Q G V +VR T+ +D + V K+ GLCGN
Sbjct: 164 HVMGSARLQQLAGYV---------IVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGN 214
Query: 1067 FNGDPADDLALRGGGQAANALAFGNSWQEETR---PGCGATEPGDCPKLDSLVAQQLQSK 1123
N DP DDL G + + F +SWQE+ PG + P L
Sbjct: 215 NNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVY 274
Query: 1124 NECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGAT 1183
+C L P PF CH+ + P C D C G C ALA YA AC AG
Sbjct: 275 EQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRP 332
Query: 1184 VHPWRSE-ELCPLSCPPHSH-YEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSG 1241
+ WR++ C + C + Y C CP SC C +GC C G
Sbjct: 333 LQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFED 392
Query: 1242 ESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGG 1301
C+ A C C GT +PPG C++ C C G C ++ C
Sbjct: 393 GGCVAPAECPCEFHGTLYPPGSVVKED--CNT-CTCTSGKW-ECSTAVC----------- 437
Query: 1302 SLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQT 1342
+ C +GD H+TTFDGRR+ F TC Y+LA++
Sbjct: 438 --------PAECSVTGDIHFTTFDGRRYTFPATCQYILAKS 470
Score = 115 bits (287), Expect = 4e-25
Identities = 111/421 (26%), Positives = 162/421 (38%), Gaps = 61/421 (14%)
Query: 790 GISVGDWRSPANCPLSCPANSRYELCGP-------ACPTSCNGAAAPSNCSGR-PCVEGC 841
G+ D R+PA +CPA + C + +C + S R PC+ GC
Sbjct: 798 GVMSCDSRAPA---AACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGC 854
Query: 842 VCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQS 901
C G + G AC C CT++G + PG +V + C C C + Q T S
Sbjct: 855 ACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSP--C-HTCVCQRGSFQCTLHPCAS 911
Query: 902 CPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL 961
TC GD HY +FDG FDF+G C LV S
Sbjct: 912 ----------------------TCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD---- 945
Query: 962 PAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADG-- 1019
+F V+VEN + S + + + + + V DD P D
Sbjct: 946 VSFSVIVENVNCYSSGMICRKFISINVGNSLI---------VFDDDSGNPSPESFLDDKQ 996
Query: 1020 QVQVFRQGRDAVVR-TDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALR 1078
+V +R G +V +T+ +D V + + L GLCGNF+ +++
Sbjct: 997 EVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTP 1056
Query: 1079 GGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRE 1138
+ N FG+SW P +P D L+ L ++ +K EC IL F
Sbjct: 1057 ENLELTNPQEFGSSWAAVECP--DTLDPRDMCVLNPL--REPFAKKECSILLSE--VFEI 1110
Query: 1139 CHSKLDPQGAVRDCVYDR--CLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLS 1196
CH +D +C+ D C G C +++ YA C G V WR+ LCP
Sbjct: 1111 CHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYD 1169
Query: 1197 C 1197
C
Sbjct: 1170 C 1170
Score = 98.6 bits (244), Expect = 4e-20
Identities = 82/297 (27%), Positives = 126/297 (42%), Gaps = 27/297 (9%)
Query: 516 CQVVGGKAGCVAESTA-VCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSV 574
C G C A C A GD HY TFDG +D +G C +V+ S+ +FSV
Sbjct: 895 CVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD----VSFSV 950
Query: 575 EAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQS 634
+N + Y + R + +S+ G V D+ + P S + + V+
Sbjct: 951 IVENVN------CYSSGMICRKF---ISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTW 1001
Query: 635 GPRAVVELVFGLV-VTYDWDCQLALSLPA--RFQDQVCGLCGNYNGDPADDFLTPDGALA 691
+ F +T WD + + + A ++Q Q+ GLCGN++ ++ TP+
Sbjct: 1002 RVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLEL 1061
Query: 692 PDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDT 751
+ EF SSW + C D C + + C +L L F +CH
Sbjct: 1062 TNPQEFGSSWAAVE----CPDTLDPR-DMCVLNPLREPFAKKECSIL--LSEVFEICHPV 1114
Query: 752 LDPRPFLEQCVYDL--CVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSC 806
+D F C+ D C GG+ C +SAYA C + G++V DWR+P CP C
Sbjct: 1115 VDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1170
Score = 91.3 bits (225), Expect = 6e-18
Identities = 115/456 (25%), Positives = 171/456 (37%), Gaps = 78/456 (17%)
Query: 480 GLAKAIGYATAADCGRTVLSPVEPSCEGMQCAAGQ-----------------RCQV---- 518
GLA+A+ T A+ T + E C C GQ RC +
Sbjct: 1962 GLAEALATTTEANTSTTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLA 2021
Query: 519 --VGGKAGC-VAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVE 575
VGG C + E C D + TFDG + Y + + S D+ L ++
Sbjct: 2022 VRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQ--SPDEMLTVHVLD 2079
Query: 576 AKNEHRGSRRVSYVGLVTVRA--YSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQ 633
K+ + G LV + +H V++ R V VD Q PVS R+
Sbjct: 2080 CKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRK-VTVDLQPVWPPVS--RYGFRIED 2136
Query: 634 SGPRAVVELVFGLVVTYDWDCQLALSLPARFQD-QVCGLCGNYNGDPADDFLTPDGAL-- 690
+G ++ + + + L + ++ Q GLCG +GD A+D DG++
Sbjct: 2137 TGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVG 2196
Query: 691 -APDAVEFASSWKLDDG------DYLCEDGCQN-NCPACTPGQAQHYEGDRLCGMLTKLD 742
A D F SW++ D C +C C R+ T
Sbjct: 2197 GAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCL----------RMVSNRT--- 2243
Query: 743 GPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANC 802
F+ CH + P F E + D V C L+ Y C + + + +WR C
Sbjct: 2244 --FSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCI-EWRRSDYC 2296
Query: 803 PLSCPANSRYELCGPAC--PTSCN----GAAAPSNCSGRPCVEGCVCLPGFV---ASGGA 853
P C ++S Y+ C AC P +C G P +C + EGCVC G +
Sbjct: 2297 PFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHC--QVLGEGCVCSEGTILHRRHSAL 2354
Query: 854 CVPASSCGCT-FQGLQLAPGQEVWADEL---CQRRC 885
C+P + C CT G+ A G E W L CQ +C
Sbjct: 2355 CIPEAKCACTDSMGVPRALG-ETWNSSLSGCCQHQC 2389
Score = 78.6 bits (192), Expect = 4e-14
Identities = 119/493 (24%), Positives = 165/493 (33%), Gaps = 111/493 (22%)
Query: 877 ADELCQRRCTCNGATHQVTCRDKQSCPAGE---RCSVQNGLLG---------CYPDRFGT 924
A++ C R G +V Q CP G RC G+LG C P
Sbjct: 1983 AEQDCVRHICLEGQLIRVN--QSQHCPQGAAPPRC----GILGLAVRVGGDRCCPLWECA 2036
Query: 925 CQGS--GDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL----------------PAFRV 966
C+ S D +V+FDG Y+L S + + P V
Sbjct: 2037 CRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLV 2096
Query: 967 LVENEHRGSQTV--SYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVF 1024
++ H Q + R V V+ + V V R G + D Y+ +D Q+Q
Sbjct: 2097 MLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRY--GFRIEDTGHMYMILTPSDIQIQWL 2154
Query: 1025 RQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGG---G 1081
+V +K + LCG+C +GD A+DL L+ G G
Sbjct: 2155 HSSGLMIVEA---------------SKTSKAQGHGLCGIC---DGDAANDLTLKDGSVVG 2196
Query: 1082 QAANALAFGNSWQEE---TRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRE 1138
A + F +SWQ T G P C D ++ S F
Sbjct: 2197 GAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRT----------FSA 2246
Query: 1139 CHSKLDPQGA----VRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCP 1194
CH + P+ +RD Y + C AL Y A C + WR + CP
Sbjct: 2247 CHRFVPPESFCELWIRDTKYVQ--------QPCVALTVYVAMCHKFHVCIE-WRRSDYCP 2297
Query: 1195 LSCPPHSHYEACSYGC--PLSCGDLPVPGGCGSECH---EGCVCDEGFAL---SGESCLP 1246
C S Y+AC C P +C D + C EGCVC EG L C+P
Sbjct: 2298 FLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIP 2357
Query: 1247 LASCGCV-HQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGC 1305
A C C G G+T+ L C C + P LGC
Sbjct: 2358 EAKCACTDSMGVPRALGETW-------------NSSLSGCCQHQCQAPDTIVPV--DLGC 2402
Query: 1306 VAVGSSTCQASGD 1318
+ +C G+
Sbjct: 2403 PSPRPESCLRFGE 2415
Score = 68.9 bits (167), Expect = 3e-11
Identities = 47/156 (30%), Positives = 66/156 (42%), Gaps = 35/156 (22%)
Query: 1227 CHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCH---CQEGGLV 1283
C GC C +G G++C C C +G + ++PG S CH CQ G
Sbjct: 850 CLSGCACPQGLLRHGDACFLPEECPCTWKG------KEYFPGDQVMSPCHTCVCQRGSF- 902
Query: 1284 SCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTC-VYVLAQT 1342
C C +STC A GD HY TFDG FDF+G C V+++ T
Sbjct: 903 QCTLHPC-------------------ASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKST 943
Query: 1343 CGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVAN 1378
F+V+ ENV + + + I++ V N
Sbjct: 944 SDV-----SFSVIVENVNCYSSGMICRKFISINVGN 974
Score = 32.7 bits (73), Expect = 2.7
Identities = 22/77 (28%), Positives = 30/77 (38%), Gaps = 11/77 (14%)
Query: 1277 CQEGGLVSCESSSCGPHEACQPSGGSLG---------CVAVGSSTCQAS--GDPHYTTFD 1325
C EG L+ S P A P G LG C + C+ S D + TFD
Sbjct: 1992 CLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFD 2051
Query: 1326 GRRFDFMGTCVYVLAQT 1342
G +Y+L+Q+
Sbjct: 2052 GSHVALFKEAIYILSQS 2068
>gi|239749987 PREDICTED: otogelin isoform 1 [Homo sapiens]
Length = 2924
Score = 280 bits (716), Expect = 7e-75
Identities = 247/825 (29%), Positives = 336/825 (40%), Gaps = 105/825 (12%)
Query: 511 AAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLP 570
A G RCQ+V E ++CRA G H TFDG Y + G SYT+V +
Sbjct: 132 ATGPRCQMVYNAG---PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQ-- 186
Query: 571 AFSVEAKNE-------HRGSRRVS--YVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLP 621
+FS++ N+ + SR VS +VG + + +T G R +LP
Sbjct: 187 SFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHL---AKEVTHG--------GMRVQLP 235
Query: 622 VSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPAD 681
+ RL+ Q +V + +D + + + GLCGN N DP D
Sbjct: 236 HVMGSARLQ--QLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKD 293
Query: 682 DFLTPDGALAPDAVEFASSWKLDDGDY--------LCEDGCQNNCPACTPGQAQHYEGDR 733
D +T G L D VEF SW+ + L C P G + E
Sbjct: 294 DLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEA-- 351
Query: 734 LCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISV 793
L PF CH + P PF C DLC G+ + CR L+ YA+AC + G +
Sbjct: 352 ------LLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 405
Query: 794 GDWRSP-ANCPLSCPANS-RYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASG 851
WR+ C + C + Y C CP SC+ A+ + S CV+GC C G +
Sbjct: 406 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVD-SEIACVDGCYCPNGLIFED 464
Query: 852 GACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQ 911
G CV + C C F G PG V D C CTC + + CPA CSV
Sbjct: 465 GGCVAPAECPCEFHGTLYPPGSVVKED--C-NTCTCTSGKWECS---TAVCPA--ECSV- 515
Query: 912 NGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENE 971
+GD H+ +FDGRR+ F TC Y+L S F V ++N
Sbjct: 516 ----------------TGDIHFTTFDGRRYTFPATCQYILAKSRSSG----TFTVTLQNA 555
Query: 972 HRG-SQTVSYTRAVRVEA-RGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRD 1029
G +Q + ++V V + + V G VL+ D + +P D ++ R
Sbjct: 556 PCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIP-PYTDDAFEIRRLSSV 614
Query: 1030 AV-VRTDFGLTVTYDWNA-RVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANAL 1087
+ VRT+ G+ V YD R+ +V + E GLCG FNG+ DD G +
Sbjct: 615 FLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQ 674
Query: 1088 AFGNSWQEETRPGCGATEPGD-CPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQ 1146
FGNSW +T C G D + S C +L F C + L P
Sbjct: 675 LFGNSW--KTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEM--FAPCSAFLSPV 730
Query: 1147 GAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEAC 1206
C D C GQ LC LA YA C+ G V C LSC Y C
Sbjct: 731 PYFEQCRRDACRC-GQP-CLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPC 788
Query: 1207 SYGCPLSCGDLPVPGGCG---------SECHEGCVC--DEGFALSGESCLPLASCGCVHQ 1255
C +C DL P CG EC EGC C D + C+P C C Q
Sbjct: 789 VAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQ 848
Query: 1256 GTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSG 1300
G +PPG + P G CHC++ G++SC+S + P AC P+G
Sbjct: 849 GVDYPPGDSDIPSLG---HCHCKD-GVMSCDSRA--PAAAC-PAG 886
Score = 162 bits (409), Expect = 3e-39
Identities = 130/461 (28%), Positives = 184/461 (39%), Gaps = 49/461 (10%)
Query: 892 HQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLL 951
H C ++ G RC + + P+R C+ G H +FDG + G +Y L
Sbjct: 121 HPAFCDCRRFNATGPRCQM---VYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTL 177
Query: 952 VGSCGQNAALPAFRVLVENEHR-GSQTVSYTRAVR---VEARGVKVAVRREYPG-QVLVD 1006
VG +F + V N+ + GS + +RAV V + + +A + G +V +
Sbjct: 178 VGRHEPEGQ--SFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLP 235
Query: 1007 DVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGN 1066
V+ Q G V +VR T+ +D + V K+ GLCGN
Sbjct: 236 HVMGSARLQQLAGYV---------IVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGN 286
Query: 1067 FNGDPADDLALRGGGQAANALAFGNSWQEETR---PGCGATEPGDCPKLDSLVAQQLQSK 1123
N DP DDL G + + F +SWQE+ PG + P L
Sbjct: 287 NNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVY 346
Query: 1124 NECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGAT 1183
+C L P PF CH+ + P C D C G C ALA YA AC AG
Sbjct: 347 EQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRP 404
Query: 1184 VHPWRSE-ELCPLSCPPHSH-YEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSG 1241
+ WR++ C + C + Y C CP SC C +GC C G
Sbjct: 405 LQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFED 464
Query: 1242 ESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGG 1301
C+ A C C GT +PPG C++ C C G C ++ C
Sbjct: 465 GGCVAPAECPCEFHGTLYPPGSVVKED--CNT-CTCTSGKW-ECSTAVC----------- 509
Query: 1302 SLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQT 1342
+ C +GD H+TTFDGRR+ F TC Y+LA++
Sbjct: 510 --------PAECSVTGDIHFTTFDGRRYTFPATCQYILAKS 542
Score = 115 bits (287), Expect = 4e-25
Identities = 111/421 (26%), Positives = 162/421 (38%), Gaps = 61/421 (14%)
Query: 790 GISVGDWRSPANCPLSCPANSRYELCGP-------ACPTSCNGAAAPSNCSGR-PCVEGC 841
G+ D R+PA +CPA + C + +C + S R PC+ GC
Sbjct: 870 GVMSCDSRAPA---AACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGC 926
Query: 842 VCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQS 901
C G + G AC C CT++G + PG +V + C C C + Q T S
Sbjct: 927 ACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSP--C-HTCVCQRGSFQCTLHPCAS 983
Query: 902 CPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL 961
TC GD HY +FDG FDF+G C LV S
Sbjct: 984 ----------------------TCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD---- 1017
Query: 962 PAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADG-- 1019
+F V+VEN + S + + + + + V DD P D
Sbjct: 1018 VSFSVIVENVNCYSSGMICRKFISINVGNSLI---------VFDDDSGNPSPESFLDDKQ 1068
Query: 1020 QVQVFRQGRDAVVR-TDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALR 1078
+V +R G +V +T+ +D V + + L GLCGNF+ +++
Sbjct: 1069 EVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTP 1128
Query: 1079 GGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRE 1138
+ N FG+SW P +P D L+ L ++ +K EC IL F
Sbjct: 1129 ENLELTNPQEFGSSWAAVECP--DTLDPRDMCVLNPL--REPFAKKECSILLSE--VFEI 1182
Query: 1139 CHSKLDPQGAVRDCVYDR--CLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLS 1196
CH +D +C+ D C G C +++ YA C G V WR+ LCP
Sbjct: 1183 CHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYD 1241
Query: 1197 C 1197
C
Sbjct: 1242 C 1242
Score = 98.6 bits (244), Expect = 4e-20
Identities = 82/297 (27%), Positives = 126/297 (42%), Gaps = 27/297 (9%)
Query: 516 CQVVGGKAGCVAESTA-VCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSV 574
C G C A C A GD HY TFDG +D +G C +V+ S+ +FSV
Sbjct: 967 CVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD----VSFSV 1022
Query: 575 EAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQS 634
+N + Y + R + +S+ G V D+ + P S + + V+
Sbjct: 1023 IVENVN------CYSSGMICRKF---ISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTW 1073
Query: 635 GPRAVVELVFGLV-VTYDWDCQLALSLPA--RFQDQVCGLCGNYNGDPADDFLTPDGALA 691
+ F +T WD + + + A ++Q Q+ GLCGN++ ++ TP+
Sbjct: 1074 RVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLEL 1133
Query: 692 PDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDT 751
+ EF SSW + C D C + + C +L L F +CH
Sbjct: 1134 TNPQEFGSSWAAVE----CPDTLDPR-DMCVLNPLREPFAKKECSIL--LSEVFEICHPV 1186
Query: 752 LDPRPFLEQCVYDL--CVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSC 806
+D F C+ D C GG+ C +SAYA C + G++V DWR+P CP C
Sbjct: 1187 VDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1242
Score = 91.3 bits (225), Expect = 6e-18
Identities = 115/456 (25%), Positives = 171/456 (37%), Gaps = 78/456 (17%)
Query: 480 GLAKAIGYATAADCGRTVLSPVEPSCEGMQCAAGQ-----------------RCQV---- 518
GLA+A+ T A+ T + E C C GQ RC +
Sbjct: 2034 GLAEALATTTEANTSTTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLA 2093
Query: 519 --VGGKAGC-VAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVE 575
VGG C + E C D + TFDG + Y + + S D+ L ++
Sbjct: 2094 VRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQ--SPDEMLTVHVLD 2151
Query: 576 AKNEHRGSRRVSYVGLVTVRA--YSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQ 633
K+ + G LV + +H V++ R V VD Q PVS R+
Sbjct: 2152 CKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRK-VTVDLQPVWPPVS--RYGFRIED 2208
Query: 634 SGPRAVVELVFGLVVTYDWDCQLALSLPARFQD-QVCGLCGNYNGDPADDFLTPDGAL-- 690
+G ++ + + + L + ++ Q GLCG +GD A+D DG++
Sbjct: 2209 TGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVG 2268
Query: 691 -APDAVEFASSWKLDDG------DYLCEDGCQN-NCPACTPGQAQHYEGDRLCGMLTKLD 742
A D F SW++ D C +C C R+ T
Sbjct: 2269 GAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCL----------RMVSNRT--- 2315
Query: 743 GPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANC 802
F+ CH + P F E + D V C L+ Y C + + + +WR C
Sbjct: 2316 --FSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCI-EWRRSDYC 2368
Query: 803 PLSCPANSRYELCGPAC--PTSCN----GAAAPSNCSGRPCVEGCVCLPGFV---ASGGA 853
P C ++S Y+ C AC P +C G P +C + EGCVC G +
Sbjct: 2369 PFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHC--QVLGEGCVCSEGTILHRRHSAL 2426
Query: 854 CVPASSCGCT-FQGLQLAPGQEVWADEL---CQRRC 885
C+P + C CT G+ A G E W L CQ +C
Sbjct: 2427 CIPEAKCACTDSMGVPRALG-ETWNSSLSGCCQHQC 2461
Score = 78.6 bits (192), Expect = 4e-14
Identities = 119/493 (24%), Positives = 165/493 (33%), Gaps = 111/493 (22%)
Query: 877 ADELCQRRCTCNGATHQVTCRDKQSCPAGE---RCSVQNGLLG---------CYPDRFGT 924
A++ C R G +V Q CP G RC G+LG C P
Sbjct: 2055 AEQDCVRHICLEGQLIRVN--QSQHCPQGAAPPRC----GILGLAVRVGGDRCCPLWECA 2108
Query: 925 CQGS--GDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL----------------PAFRV 966
C+ S D +V+FDG Y+L S + + P V
Sbjct: 2109 CRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLV 2168
Query: 967 LVENEHRGSQTV--SYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVF 1024
++ H Q + R V V+ + V V R G + D Y+ +D Q+Q
Sbjct: 2169 MLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRY--GFRIEDTGHMYMILTPSDIQIQWL 2226
Query: 1025 RQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGG---G 1081
+V +K + LCG+C +GD A+DL L+ G G
Sbjct: 2227 HSSGLMIVEA---------------SKTSKAQGHGLCGIC---DGDAANDLTLKDGSVVG 2268
Query: 1082 QAANALAFGNSWQEE---TRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRE 1138
A + F +SWQ T G P C D ++ S F
Sbjct: 2269 GAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRT----------FSA 2318
Query: 1139 CHSKLDPQGA----VRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCP 1194
CH + P+ +RD Y + C AL Y A C + WR + CP
Sbjct: 2319 CHRFVPPESFCELWIRDTKYVQ--------QPCVALTVYVAMCHKFHVCIE-WRRSDYCP 2369
Query: 1195 LSCPPHSHYEACSYGC--PLSCGDLPVPGGCGSECH---EGCVCDEGFAL---SGESCLP 1246
C S Y+AC C P +C D + C EGCVC EG L C+P
Sbjct: 2370 FLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIP 2429
Query: 1247 LASCGCV-HQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGC 1305
A C C G G+T+ L C C + P LGC
Sbjct: 2430 EAKCACTDSMGVPRALGETW-------------NSSLSGCCQHQCQAPDTIVPV--DLGC 2474
Query: 1306 VAVGSSTCQASGD 1318
+ +C G+
Sbjct: 2475 PSPRPESCLRFGE 2487
Score = 68.9 bits (167), Expect = 3e-11
Identities = 47/156 (30%), Positives = 66/156 (42%), Gaps = 35/156 (22%)
Query: 1227 CHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCH---CQEGGLV 1283
C GC C +G G++C C C +G + ++PG S CH CQ G
Sbjct: 922 CLSGCACPQGLLRHGDACFLPEECPCTWKG------KEYFPGDQVMSPCHTCVCQRGSF- 974
Query: 1284 SCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTC-VYVLAQT 1342
C C +STC A GD HY TFDG FDF+G C V+++ T
Sbjct: 975 QCTLHPC-------------------ASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKST 1015
Query: 1343 CGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVAN 1378
F+V+ ENV + + + I++ V N
Sbjct: 1016 SDV-----SFSVIVENVNCYSSGMICRKFISINVGN 1046
Score = 32.7 bits (73), Expect = 2.7
Identities = 22/77 (28%), Positives = 30/77 (38%), Gaps = 11/77 (14%)
Query: 1277 CQEGGLVSCESSSCGPHEACQPSGGSLG---------CVAVGSSTCQAS--GDPHYTTFD 1325
C EG L+ S P A P G LG C + C+ S D + TFD
Sbjct: 2064 CLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFD 2123
Query: 1326 GRRFDFMGTCVYVLAQT 1342
G +Y+L+Q+
Sbjct: 2124 GSHVALFKEAIYILSQS 2140
>gi|239744300 PREDICTED: otogelin isoform 2 [Homo sapiens]
Length = 2852
Score = 280 bits (716), Expect = 7e-75
Identities = 247/825 (29%), Positives = 336/825 (40%), Gaps = 105/825 (12%)
Query: 511 AAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLP 570
A G RCQ+V E ++CRA G H TFDG Y + G SYT+V +
Sbjct: 60 ATGPRCQMVYNAG---PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQ-- 114
Query: 571 AFSVEAKNE-------HRGSRRVS--YVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLP 621
+FS++ N+ + SR VS +VG + + +T G R +LP
Sbjct: 115 SFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHL---AKEVTHG--------GMRVQLP 163
Query: 622 VSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPAD 681
+ RL+ Q +V + +D + + + GLCGN N DP D
Sbjct: 164 HVMGSARLQ--QLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKD 221
Query: 682 DFLTPDGALAPDAVEFASSWKLDDGDY--------LCEDGCQNNCPACTPGQAQHYEGDR 733
D +T G L D VEF SW+ + L C P G + E
Sbjct: 222 DLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEA-- 279
Query: 734 LCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISV 793
L PF CH + P PF C DLC G+ + CR L+ YA+AC + G +
Sbjct: 280 ------LLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 333
Query: 794 GDWRSP-ANCPLSCPANS-RYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASG 851
WR+ C + C + Y C CP SC+ A+ + S CV+GC C G +
Sbjct: 334 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVD-SEIACVDGCYCPNGLIFED 392
Query: 852 GACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQ 911
G CV + C C F G PG V D C CTC + + CPA CSV
Sbjct: 393 GGCVAPAECPCEFHGTLYPPGSVVKED--C-NTCTCTSGKWECS---TAVCPA--ECSV- 443
Query: 912 NGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENE 971
+GD H+ +FDGRR+ F TC Y+L S F V ++N
Sbjct: 444 ----------------TGDIHFTTFDGRRYTFPATCQYILAKSRSSG----TFTVTLQNA 483
Query: 972 HRG-SQTVSYTRAVRVEA-RGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRD 1029
G +Q + ++V V + + V G VL+ D + +P D ++ R
Sbjct: 484 PCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIP-PYTDDAFEIRRLSSV 542
Query: 1030 AV-VRTDFGLTVTYDWNA-RVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANAL 1087
+ VRT+ G+ V YD R+ +V + E GLCG FNG+ DD G +
Sbjct: 543 FLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQ 602
Query: 1088 AFGNSWQEETRPGCGATEPGD-CPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQ 1146
FGNSW +T C G D + S C +L F C + L P
Sbjct: 603 LFGNSW--KTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEM--FAPCSAFLSPV 658
Query: 1147 GAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEAC 1206
C D C GQ LC LA YA C+ G V C LSC Y C
Sbjct: 659 PYFEQCRRDACRC-GQP-CLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPC 716
Query: 1207 SYGCPLSCGDLPVPGGCG---------SECHEGCVC--DEGFALSGESCLPLASCGCVHQ 1255
C +C DL P CG EC EGC C D + C+P C C Q
Sbjct: 717 VAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQ 776
Query: 1256 GTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSG 1300
G +PPG + P G CHC++ G++SC+S + P AC P+G
Sbjct: 777 GVDYPPGDSDIPSLG---HCHCKD-GVMSCDSRA--PAAAC-PAG 814
Score = 162 bits (409), Expect = 3e-39
Identities = 130/461 (28%), Positives = 184/461 (39%), Gaps = 49/461 (10%)
Query: 892 HQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLL 951
H C ++ G RC + + P+R C+ G H +FDG + G +Y L
Sbjct: 49 HPAFCDCRRFNATGPRCQM---VYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTL 105
Query: 952 VGSCGQNAALPAFRVLVENEHR-GSQTVSYTRAVR---VEARGVKVAVRREYPG-QVLVD 1006
VG +F + V N+ + GS + +RAV V + + +A + G +V +
Sbjct: 106 VGRHEPEGQ--SFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLP 163
Query: 1007 DVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGN 1066
V+ Q G V +VR T+ +D + V K+ GLCGN
Sbjct: 164 HVMGSARLQQLAGYV---------IVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGN 214
Query: 1067 FNGDPADDLALRGGGQAANALAFGNSWQEETR---PGCGATEPGDCPKLDSLVAQQLQSK 1123
N DP DDL G + + F +SWQE+ PG + P L
Sbjct: 215 NNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVY 274
Query: 1124 NECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGAT 1183
+C L P PF CH+ + P C D C G C ALA YA AC AG
Sbjct: 275 EQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRP 332
Query: 1184 VHPWRSE-ELCPLSCPPHSH-YEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSG 1241
+ WR++ C + C + Y C CP SC C +GC C G
Sbjct: 333 LQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFED 392
Query: 1242 ESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGG 1301
C+ A C C GT +PPG C++ C C G C ++ C
Sbjct: 393 GGCVAPAECPCEFHGTLYPPGSVVKED--CNT-CTCTSGKW-ECSTAVC----------- 437
Query: 1302 SLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQT 1342
+ C +GD H+TTFDGRR+ F TC Y+LA++
Sbjct: 438 --------PAECSVTGDIHFTTFDGRRYTFPATCQYILAKS 470
Score = 115 bits (287), Expect = 4e-25
Identities = 111/421 (26%), Positives = 162/421 (38%), Gaps = 61/421 (14%)
Query: 790 GISVGDWRSPANCPLSCPANSRYELCGP-------ACPTSCNGAAAPSNCSGR-PCVEGC 841
G+ D R+PA +CPA + C + +C + S R PC+ GC
Sbjct: 798 GVMSCDSRAPA---AACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGC 854
Query: 842 VCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQS 901
C G + G AC C CT++G + PG +V + C C C + Q T S
Sbjct: 855 ACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSP--C-HTCVCQRGSFQCTLHPCAS 911
Query: 902 CPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL 961
TC GD HY +FDG FDF+G C LV S
Sbjct: 912 ----------------------TCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD---- 945
Query: 962 PAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADG-- 1019
+F V+VEN + S + + + + + V DD P D
Sbjct: 946 VSFSVIVENVNCYSSGMICRKFISINVGNSLI---------VFDDDSGNPSPESFLDDKQ 996
Query: 1020 QVQVFRQGRDAVVR-TDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALR 1078
+V +R G +V +T+ +D V + + L GLCGNF+ +++
Sbjct: 997 EVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTP 1056
Query: 1079 GGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRE 1138
+ N FG+SW P +P D L+ L ++ +K EC IL F
Sbjct: 1057 ENLELTNPQEFGSSWAAVECP--DTLDPRDMCVLNPL--REPFAKKECSILLSE--VFEI 1110
Query: 1139 CHSKLDPQGAVRDCVYDR--CLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLS 1196
CH +D +C+ D C G C +++ YA C G V WR+ LCP
Sbjct: 1111 CHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYD 1169
Query: 1197 C 1197
C
Sbjct: 1170 C 1170
Score = 98.6 bits (244), Expect = 4e-20
Identities = 82/297 (27%), Positives = 126/297 (42%), Gaps = 27/297 (9%)
Query: 516 CQVVGGKAGCVAESTA-VCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSV 574
C G C A C A GD HY TFDG +D +G C +V+ S+ +FSV
Sbjct: 895 CVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD----VSFSV 950
Query: 575 EAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQS 634
+N + Y + R + +S+ G V D+ + P S + + V+
Sbjct: 951 IVENVN------CYSSGMICRKF---ISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTW 1001
Query: 635 GPRAVVELVFGLV-VTYDWDCQLALSLPA--RFQDQVCGLCGNYNGDPADDFLTPDGALA 691
+ F +T WD + + + A ++Q Q+ GLCGN++ ++ TP+
Sbjct: 1002 RVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLEL 1061
Query: 692 PDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDT 751
+ EF SSW + C D C + + C +L L F +CH
Sbjct: 1062 TNPQEFGSSWAAVE----CPDTLDPR-DMCVLNPLREPFAKKECSIL--LSEVFEICHPV 1114
Query: 752 LDPRPFLEQCVYDL--CVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSC 806
+D F C+ D C GG+ C +SAYA C + G++V DWR+P CP C
Sbjct: 1115 VDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1170
Score = 91.3 bits (225), Expect = 6e-18
Identities = 115/456 (25%), Positives = 171/456 (37%), Gaps = 78/456 (17%)
Query: 480 GLAKAIGYATAADCGRTVLSPVEPSCEGMQCAAGQ-----------------RCQV---- 518
GLA+A+ T A+ T + E C C GQ RC +
Sbjct: 1962 GLAEALATTTEANTSTTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLA 2021
Query: 519 --VGGKAGC-VAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVE 575
VGG C + E C D + TFDG + Y + + S D+ L ++
Sbjct: 2022 VRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQ--SPDEMLTVHVLD 2079
Query: 576 AKNEHRGSRRVSYVGLVTVRA--YSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQ 633
K+ + G LV + +H V++ R V VD Q PVS R+
Sbjct: 2080 CKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRK-VTVDLQPVWPPVS--RYGFRIED 2136
Query: 634 SGPRAVVELVFGLVVTYDWDCQLALSLPARFQD-QVCGLCGNYNGDPADDFLTPDGAL-- 690
+G ++ + + + L + ++ Q GLCG +GD A+D DG++
Sbjct: 2137 TGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVG 2196
Query: 691 -APDAVEFASSWKLDDG------DYLCEDGCQN-NCPACTPGQAQHYEGDRLCGMLTKLD 742
A D F SW++ D C +C C R+ T
Sbjct: 2197 GAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCL----------RMVSNRT--- 2243
Query: 743 GPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANC 802
F+ CH + P F E + D V C L+ Y C + + + +WR C
Sbjct: 2244 --FSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCI-EWRRSDYC 2296
Query: 803 PLSCPANSRYELCGPAC--PTSCN----GAAAPSNCSGRPCVEGCVCLPGFV---ASGGA 853
P C ++S Y+ C AC P +C G P +C + EGCVC G +
Sbjct: 2297 PFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHC--QVLGEGCVCSEGTILHRRHSAL 2354
Query: 854 CVPASSCGCT-FQGLQLAPGQEVWADEL---CQRRC 885
C+P + C CT G+ A G E W L CQ +C
Sbjct: 2355 CIPEAKCACTDSMGVPRALG-ETWNSSLSGCCQHQC 2389
Score = 78.6 bits (192), Expect = 4e-14
Identities = 119/493 (24%), Positives = 165/493 (33%), Gaps = 111/493 (22%)
Query: 877 ADELCQRRCTCNGATHQVTCRDKQSCPAGE---RCSVQNGLLG---------CYPDRFGT 924
A++ C R G +V Q CP G RC G+LG C P
Sbjct: 1983 AEQDCVRHICLEGQLIRVN--QSQHCPQGAAPPRC----GILGLAVRVGGDRCCPLWECA 2036
Query: 925 CQGS--GDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL----------------PAFRV 966
C+ S D +V+FDG Y+L S + + P V
Sbjct: 2037 CRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLV 2096
Query: 967 LVENEHRGSQTV--SYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVF 1024
++ H Q + R V V+ + V V R G + D Y+ +D Q+Q
Sbjct: 2097 MLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRY--GFRIEDTGHMYMILTPSDIQIQWL 2154
Query: 1025 RQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGG---G 1081
+V +K + LCG+C +GD A+DL L+ G G
Sbjct: 2155 HSSGLMIVEA---------------SKTSKAQGHGLCGIC---DGDAANDLTLKDGSVVG 2196
Query: 1082 QAANALAFGNSWQEE---TRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRE 1138
A + F +SWQ T G P C D ++ S F
Sbjct: 2197 GAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRT----------FSA 2246
Query: 1139 CHSKLDPQGA----VRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCP 1194
CH + P+ +RD Y + C AL Y A C + WR + CP
Sbjct: 2247 CHRFVPPESFCELWIRDTKYVQ--------QPCVALTVYVAMCHKFHVCIE-WRRSDYCP 2297
Query: 1195 LSCPPHSHYEACSYGC--PLSCGDLPVPGGCGSECH---EGCVCDEGFAL---SGESCLP 1246
C S Y+AC C P +C D + C EGCVC EG L C+P
Sbjct: 2298 FLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIP 2357
Query: 1247 LASCGCV-HQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGC 1305
A C C G G+T+ L C C + P LGC
Sbjct: 2358 EAKCACTDSMGVPRALGETW-------------NSSLSGCCQHQCQAPDTIVPV--DLGC 2402
Query: 1306 VAVGSSTCQASGD 1318
+ +C G+
Sbjct: 2403 PSPRPESCLRFGE 2415
Score = 68.9 bits (167), Expect = 3e-11
Identities = 47/156 (30%), Positives = 66/156 (42%), Gaps = 35/156 (22%)
Query: 1227 CHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCH---CQEGGLV 1283
C GC C +G G++C C C +G + ++PG S CH CQ G
Sbjct: 850 CLSGCACPQGLLRHGDACFLPEECPCTWKG------KEYFPGDQVMSPCHTCVCQRGSF- 902
Query: 1284 SCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTC-VYVLAQT 1342
C C +STC A GD HY TFDG FDF+G C V+++ T
Sbjct: 903 QCTLHPC-------------------ASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKST 943
Query: 1343 CGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVAN 1378
F+V+ ENV + + + I++ V N
Sbjct: 944 SDV-----SFSVIVENVNCYSSGMICRKFISINVGN 974
Score = 32.7 bits (73), Expect = 2.7
Identities = 22/77 (28%), Positives = 30/77 (38%), Gaps = 11/77 (14%)
Query: 1277 CQEGGLVSCESSSCGPHEACQPSGGSLG---------CVAVGSSTCQAS--GDPHYTTFD 1325
C EG L+ S P A P G LG C + C+ S D + TFD
Sbjct: 1992 CLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFD 2051
Query: 1326 GRRFDFMGTCVYVLAQT 1342
G +Y+L+Q+
Sbjct: 2052 GSHVALFKEAIYILSQS 2068
>gi|239744298 PREDICTED: otogelin isoform 1 [Homo sapiens]
Length = 2924
Score = 280 bits (716), Expect = 7e-75
Identities = 247/825 (29%), Positives = 336/825 (40%), Gaps = 105/825 (12%)
Query: 511 AAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLP 570
A G RCQ+V E ++CRA G H TFDG Y + G SYT+V +
Sbjct: 132 ATGPRCQMVYNAG---PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQ-- 186
Query: 571 AFSVEAKNE-------HRGSRRVS--YVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLP 621
+FS++ N+ + SR VS +VG + + +T G R +LP
Sbjct: 187 SFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHL---AKEVTHG--------GMRVQLP 235
Query: 622 VSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPAD 681
+ RL+ Q +V + +D + + + GLCGN N DP D
Sbjct: 236 HVMGSARLQ--QLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKD 293
Query: 682 DFLTPDGALAPDAVEFASSWKLDDGDY--------LCEDGCQNNCPACTPGQAQHYEGDR 733
D +T G L D VEF SW+ + L C P G + E
Sbjct: 294 DLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEA-- 351
Query: 734 LCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISV 793
L PF CH + P PF C DLC G+ + CR L+ YA+AC + G +
Sbjct: 352 ------LLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 405
Query: 794 GDWRSP-ANCPLSCPANS-RYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASG 851
WR+ C + C + Y C CP SC+ A+ + S CV+GC C G +
Sbjct: 406 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVD-SEIACVDGCYCPNGLIFED 464
Query: 852 GACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQ 911
G CV + C C F G PG V D C CTC + + CPA CSV
Sbjct: 465 GGCVAPAECPCEFHGTLYPPGSVVKED--C-NTCTCTSGKWECS---TAVCPA--ECSV- 515
Query: 912 NGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENE 971
+GD H+ +FDGRR+ F TC Y+L S F V ++N
Sbjct: 516 ----------------TGDIHFTTFDGRRYTFPATCQYILAKSRSSG----TFTVTLQNA 555
Query: 972 HRG-SQTVSYTRAVRVEA-RGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRD 1029
G +Q + ++V V + + V G VL+ D + +P D ++ R
Sbjct: 556 PCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIP-PYTDDAFEIRRLSSV 614
Query: 1030 AV-VRTDFGLTVTYDWNA-RVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANAL 1087
+ VRT+ G+ V YD R+ +V + E GLCG FNG+ DD G +
Sbjct: 615 FLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQ 674
Query: 1088 AFGNSWQEETRPGCGATEPGD-CPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQ 1146
FGNSW +T C G D + S C +L F C + L P
Sbjct: 675 LFGNSW--KTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEM--FAPCSAFLSPV 730
Query: 1147 GAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEAC 1206
C D C GQ LC LA YA C+ G V C LSC Y C
Sbjct: 731 PYFEQCRRDACRC-GQP-CLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPC 788
Query: 1207 SYGCPLSCGDLPVPGGCG---------SECHEGCVC--DEGFALSGESCLPLASCGCVHQ 1255
C +C DL P CG EC EGC C D + C+P C C Q
Sbjct: 789 VAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQ 848
Query: 1256 GTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSG 1300
G +PPG + P G CHC++ G++SC+S + P AC P+G
Sbjct: 849 GVDYPPGDSDIPSLG---HCHCKD-GVMSCDSRA--PAAAC-PAG 886
Score = 162 bits (409), Expect = 3e-39
Identities = 130/461 (28%), Positives = 184/461 (39%), Gaps = 49/461 (10%)
Query: 892 HQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLL 951
H C ++ G RC + + P+R C+ G H +FDG + G +Y L
Sbjct: 121 HPAFCDCRRFNATGPRCQM---VYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTL 177
Query: 952 VGSCGQNAALPAFRVLVENEHR-GSQTVSYTRAVR---VEARGVKVAVRREYPG-QVLVD 1006
VG +F + V N+ + GS + +RAV V + + +A + G +V +
Sbjct: 178 VGRHEPEGQ--SFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLP 235
Query: 1007 DVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGN 1066
V+ Q G V +VR T+ +D + V K+ GLCGN
Sbjct: 236 HVMGSARLQQLAGYV---------IVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGN 286
Query: 1067 FNGDPADDLALRGGGQAANALAFGNSWQEETR---PGCGATEPGDCPKLDSLVAQQLQSK 1123
N DP DDL G + + F +SWQE+ PG + P L
Sbjct: 287 NNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVY 346
Query: 1124 NECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGAT 1183
+C L P PF CH+ + P C D C G C ALA YA AC AG
Sbjct: 347 EQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRP 404
Query: 1184 VHPWRSE-ELCPLSCPPHSH-YEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSG 1241
+ WR++ C + C + Y C CP SC C +GC C G
Sbjct: 405 LQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFED 464
Query: 1242 ESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGG 1301
C+ A C C GT +PPG C++ C C G C ++ C
Sbjct: 465 GGCVAPAECPCEFHGTLYPPGSVVKED--CNT-CTCTSGKW-ECSTAVC----------- 509
Query: 1302 SLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQT 1342
+ C +GD H+TTFDGRR+ F TC Y+LA++
Sbjct: 510 --------PAECSVTGDIHFTTFDGRRYTFPATCQYILAKS 542
Score = 115 bits (287), Expect = 4e-25
Identities = 111/421 (26%), Positives = 162/421 (38%), Gaps = 61/421 (14%)
Query: 790 GISVGDWRSPANCPLSCPANSRYELCGP-------ACPTSCNGAAAPSNCSGR-PCVEGC 841
G+ D R+PA +CPA + C + +C + S R PC+ GC
Sbjct: 870 GVMSCDSRAPA---AACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGC 926
Query: 842 VCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQS 901
C G + G AC C CT++G + PG +V + C C C + Q T S
Sbjct: 927 ACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSP--C-HTCVCQRGSFQCTLHPCAS 983
Query: 902 CPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL 961
TC GD HY +FDG FDF+G C LV S
Sbjct: 984 ----------------------TCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD---- 1017
Query: 962 PAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADG-- 1019
+F V+VEN + S + + + + + V DD P D
Sbjct: 1018 VSFSVIVENVNCYSSGMICRKFISINVGNSLI---------VFDDDSGNPSPESFLDDKQ 1068
Query: 1020 QVQVFRQGRDAVVR-TDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALR 1078
+V +R G +V +T+ +D V + + L GLCGNF+ +++
Sbjct: 1069 EVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTP 1128
Query: 1079 GGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRE 1138
+ N FG+SW P +P D L+ L ++ +K EC IL F
Sbjct: 1129 ENLELTNPQEFGSSWAAVECP--DTLDPRDMCVLNPL--REPFAKKECSILLSE--VFEI 1182
Query: 1139 CHSKLDPQGAVRDCVYDR--CLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLS 1196
CH +D +C+ D C G C +++ YA C G V WR+ LCP
Sbjct: 1183 CHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYD 1241
Query: 1197 C 1197
C
Sbjct: 1242 C 1242
Score = 98.6 bits (244), Expect = 4e-20
Identities = 82/297 (27%), Positives = 126/297 (42%), Gaps = 27/297 (9%)
Query: 516 CQVVGGKAGCVAESTA-VCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSV 574
C G C A C A GD HY TFDG +D +G C +V+ S+ +FSV
Sbjct: 967 CVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD----VSFSV 1022
Query: 575 EAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQS 634
+N + Y + R + +S+ G V D+ + P S + + V+
Sbjct: 1023 IVENVN------CYSSGMICRKF---ISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTW 1073
Query: 635 GPRAVVELVFGLV-VTYDWDCQLALSLPA--RFQDQVCGLCGNYNGDPADDFLTPDGALA 691
+ F +T WD + + + A ++Q Q+ GLCGN++ ++ TP+
Sbjct: 1074 RVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLEL 1133
Query: 692 PDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDT 751
+ EF SSW + C D C + + C +L L F +CH
Sbjct: 1134 TNPQEFGSSWAAVE----CPDTLDPR-DMCVLNPLREPFAKKECSIL--LSEVFEICHPV 1186
Query: 752 LDPRPFLEQCVYDL--CVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSC 806
+D F C+ D C GG+ C +SAYA C + G++V DWR+P CP C
Sbjct: 1187 VDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1242
Score = 91.3 bits (225), Expect = 6e-18
Identities = 115/456 (25%), Positives = 171/456 (37%), Gaps = 78/456 (17%)
Query: 480 GLAKAIGYATAADCGRTVLSPVEPSCEGMQCAAGQ-----------------RCQV---- 518
GLA+A+ T A+ T + E C C GQ RC +
Sbjct: 2034 GLAEALATTTEANTSTTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLA 2093
Query: 519 --VGGKAGC-VAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVE 575
VGG C + E C D + TFDG + Y + + S D+ L ++
Sbjct: 2094 VRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQ--SPDEMLTVHVLD 2151
Query: 576 AKNEHRGSRRVSYVGLVTVRA--YSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQ 633
K+ + G LV + +H V++ R V VD Q PVS R+
Sbjct: 2152 CKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRK-VTVDLQPVWPPVS--RYGFRIED 2208
Query: 634 SGPRAVVELVFGLVVTYDWDCQLALSLPARFQD-QVCGLCGNYNGDPADDFLTPDGAL-- 690
+G ++ + + + L + ++ Q GLCG +GD A+D DG++
Sbjct: 2209 TGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVG 2268
Query: 691 -APDAVEFASSWKLDDG------DYLCEDGCQN-NCPACTPGQAQHYEGDRLCGMLTKLD 742
A D F SW++ D C +C C R+ T
Sbjct: 2269 GAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCL----------RMVSNRT--- 2315
Query: 743 GPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANC 802
F+ CH + P F E + D V C L+ Y C + + + +WR C
Sbjct: 2316 --FSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCI-EWRRSDYC 2368
Query: 803 PLSCPANSRYELCGPAC--PTSCN----GAAAPSNCSGRPCVEGCVCLPGFV---ASGGA 853
P C ++S Y+ C AC P +C G P +C + EGCVC G +
Sbjct: 2369 PFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHC--QVLGEGCVCSEGTILHRRHSAL 2426
Query: 854 CVPASSCGCT-FQGLQLAPGQEVWADEL---CQRRC 885
C+P + C CT G+ A G E W L CQ +C
Sbjct: 2427 CIPEAKCACTDSMGVPRALG-ETWNSSLSGCCQHQC 2461
Score = 78.6 bits (192), Expect = 4e-14
Identities = 119/493 (24%), Positives = 165/493 (33%), Gaps = 111/493 (22%)
Query: 877 ADELCQRRCTCNGATHQVTCRDKQSCPAGE---RCSVQNGLLG---------CYPDRFGT 924
A++ C R G +V Q CP G RC G+LG C P
Sbjct: 2055 AEQDCVRHICLEGQLIRVN--QSQHCPQGAAPPRC----GILGLAVRVGGDRCCPLWECA 2108
Query: 925 CQGS--GDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL----------------PAFRV 966
C+ S D +V+FDG Y+L S + + P V
Sbjct: 2109 CRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLV 2168
Query: 967 LVENEHRGSQTV--SYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVF 1024
++ H Q + R V V+ + V V R G + D Y+ +D Q+Q
Sbjct: 2169 MLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRY--GFRIEDTGHMYMILTPSDIQIQWL 2226
Query: 1025 RQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGG---G 1081
+V +K + LCG+C +GD A+DL L+ G G
Sbjct: 2227 HSSGLMIVEA---------------SKTSKAQGHGLCGIC---DGDAANDLTLKDGSVVG 2268
Query: 1082 QAANALAFGNSWQEE---TRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRE 1138
A + F +SWQ T G P C D ++ S F
Sbjct: 2269 GAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRT----------FSA 2318
Query: 1139 CHSKLDPQGA----VRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCP 1194
CH + P+ +RD Y + C AL Y A C + WR + CP
Sbjct: 2319 CHRFVPPESFCELWIRDTKYVQ--------QPCVALTVYVAMCHKFHVCIE-WRRSDYCP 2369
Query: 1195 LSCPPHSHYEACSYGC--PLSCGDLPVPGGCGSECH---EGCVCDEGFAL---SGESCLP 1246
C S Y+AC C P +C D + C EGCVC EG L C+P
Sbjct: 2370 FLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIP 2429
Query: 1247 LASCGCV-HQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGC 1305
A C C G G+T+ L C C + P LGC
Sbjct: 2430 EAKCACTDSMGVPRALGETW-------------NSSLSGCCQHQCQAPDTIVPV--DLGC 2474
Query: 1306 VAVGSSTCQASGD 1318
+ +C G+
Sbjct: 2475 PSPRPESCLRFGE 2487
Score = 68.9 bits (167), Expect = 3e-11
Identities = 47/156 (30%), Positives = 66/156 (42%), Gaps = 35/156 (22%)
Query: 1227 CHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCH---CQEGGLV 1283
C GC C +G G++C C C +G + ++PG S CH CQ G
Sbjct: 922 CLSGCACPQGLLRHGDACFLPEECPCTWKG------KEYFPGDQVMSPCHTCVCQRGSF- 974
Query: 1284 SCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTC-VYVLAQT 1342
C C +STC A GD HY TFDG FDF+G C V+++ T
Sbjct: 975 QCTLHPC-------------------ASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKST 1015
Query: 1343 CGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVAN 1378
F+V+ ENV + + + I++ V N
Sbjct: 1016 SDV-----SFSVIVENVNCYSSGMICRKFISINVGN 1046
Score = 32.7 bits (73), Expect = 2.7
Identities = 22/77 (28%), Positives = 30/77 (38%), Gaps = 11/77 (14%)
Query: 1277 CQEGGLVSCESSSCGPHEACQPSGGSLG---------CVAVGSSTCQAS--GDPHYTTFD 1325
C EG L+ S P A P G LG C + C+ S D + TFD
Sbjct: 2064 CLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFD 2123
Query: 1326 GRRFDFMGTCVYVLAQT 1342
G +Y+L+Q+
Sbjct: 2124 GSHVALFKEAIYILSQS 2140
>gi|239755901 PREDICTED: chromosome 12 open reading frame 64 [Homo
sapiens]
Length = 2250
Score = 268 bits (684), Expect = 4e-71
Identities = 239/953 (25%), Positives = 385/953 (40%), Gaps = 146/953 (15%)
Query: 511 AAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLP 570
A G RCQ++ +C+ G H+ TFDG Y G CSY + C D P
Sbjct: 45 ALGTRCQIIPNMGN---GRDGICKTWGQYHFETFDGIYYYFPGNCSYIFAKDCG--DLEP 99
Query: 571 AFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSL---TRGEVGFVLVDNQRSRLPVSLSE- 626
++V N + L +V + S+SL + E+ + +++ + ++L +
Sbjct: 100 RYTVWVHNSPKC--------LGSVYSCYRSISLFFSNQEEIRIYGHEIKKNGISLTLPQT 151
Query: 627 -GRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLT 685
G++ + + +V+ FG + +D + L L + + CGLCGNYN +DDF+
Sbjct: 152 IGQIFIEKLADYILVKTTFGFSLAWDGISGIYLKLSEDHKGKSCGLCGNYNDIQSDDFII 211
Query: 686 PDGALAPDAVEFASSWKLDDGD----YLCEDGCQNNCPACTPG-QAQHYEGDRLCGMLTK 740
D FA+SW + D L N C + P +A ++ C +L
Sbjct: 212 LQEDYTEDIAMFANSWSVQTPDDTKCVLTPSDFPNPCSSGMPAFEAIFFK----CQIL-- 265
Query: 741 LDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRS-- 798
L PF CH+ +DP ++ CV DLC + + CR + YA+AC G + DWR
Sbjct: 266 LQFPFLSCHEYIDPYLYIASCVNDLCKTDDDE-TYCRAATEYARACSHAGYPIQDWRDDF 324
Query: 799 PANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGR--PCVEGCVCLPGFVASGGACVP 856
PA C C + + C CP +C C G C++GC C G V G C+
Sbjct: 325 PA-CTDKCDDSFVHRDCISCCPPTC---TFEKQCLGSNLHCLDGCYCPDGLVMDNGTCIS 380
Query: 857 ASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLG 916
+C C F GL + G ++ ++ C C C G T +Q CP +CSV
Sbjct: 381 LENCPCGFHGLAYSVGSKI--EQEC-TECVCVGGVWNCT---EQDCPV--QCSV------ 426
Query: 917 CYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQ 976
GD H+ +FDGR + F+G C Y+LV G++ + ++ G
Sbjct: 427 -----------VGDSHFTTFDGRHYSFIGMCQYILVKGTGKDKFTITLQKAPCEQNLGLV 475
Query: 977 TVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQA--ADGQVQV-FRQGRDAVVR 1033
+ + + +V + R GQ+L P Q +G V++ +++
Sbjct: 476 CLQSITLILEDDFNKQVTLGR--GGQILTS------PNQGFNLNGIVEIQTLSSLFILLK 527
Query: 1034 TDFGLTVTYDWNA-RVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNS 1092
T FGL + + + R+ ++ S++ GLCG FNG+ DD G N+
Sbjct: 528 TTFGLKILFAIDGERIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEGTPQLHANA 587
Query: 1093 WQEETRPGCGATEPGDCPKLD--SLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVR 1150
W+ + C A P P +D ++ Q + C ++ F CH + P +
Sbjct: 588 WRVSST--CFA--PVHVPVVDPCNINQQNIGYAAHCDVIHQEL--FAPCHIYISPGLYYQ 641
Query: 1151 DCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGC 1210
C +D C S LC+ALA YA C G + C + C Y CS C
Sbjct: 642 LCRHDACKC--GSSCLCNALAHYAYLCGQHGVPIDFRTQISFCAVVCQKGMLYHHCSSFC 699
Query: 1211 PLSCGDLPVPGGCGSECHEGCVCDEG--FALSGESCLPLASCGCVHQGTYHPPGQTFYPG 1268
SC L P C +C EGC C EG + + C+P+ C C ++G+ + PG+
Sbjct: 700 LHSCISLSSPEQCSDDCAEGCNCPEGKFYEDTLNFCVPIFHCRCHYRGSVYQPGELI--- 756
Query: 1269 PGCDSLCHCQEG----------------------------------GLVSCES--SSCGP 1292
P LC C G G V+CE+ ++
Sbjct: 757 PTPSGLCQCSNGTVKCDELATPSAVHICPEGKEYFDCRFPDPELPAGGVNCETTCANLAM 816
Query: 1293 HEACQPSGGSL-GCVAVGS---------------STCQASGDPHYTTFDGRRFDFMGTCV 1336
+ C PS + GCV + C GD HY +FDG +D++ C
Sbjct: 817 NFTCTPSSPCISGCVCAPGVCRRGMFNCTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQ 876
Query: 1337 YVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWK 1389
L ++ +V+ +N + + ++ + + V + + L +K
Sbjct: 877 VFLIKSADDSD----ISVIAQNKKCFDNDIVCSKSVLISVGDTEIYLNDTPYK 925
Score = 201 bits (512), Expect = 3e-51
Identities = 195/769 (25%), Positives = 303/769 (39%), Gaps = 120/769 (15%)
Query: 516 CQVVGGKAGCVAESTAV-CRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSV 574
C VGG C + V C GD H+TTFDGR Y +G C Y +V+ +D
Sbjct: 406 CVCVGGVWNCTEQDCPVQCSVVGDSHFTTFDGRHYSFIGMCQYILVKGTGKDKFTITLQK 465
Query: 575 EAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVD-NQRSRLPVSLSEGRLRVYQ 633
++ G + + L+ ++ V+L RG G +L NQ L + L
Sbjct: 466 APCEQNLGLVCLQSITLILEDDFNKQVTLGRG--GQILTSPNQGFNLNGIVEIQTL---- 519
Query: 634 SGPRAVVELVFGLVVTYDWDCQ-LALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAP 692
S +++ FGL + + D + + + L + ++ + GLCG +NG+ DDFL+P G +
Sbjct: 520 SSLFILLKTTFGLKILFAIDGERIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEG 579
Query: 693 DAVEFASSWKLDDGDYL-----CEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAV 747
A++W++ + D C N G A H C ++ + FA
Sbjct: 580 TPQLHANAWRVSSTCFAPVHVPVVDPCNINQQNI--GYAAH------CDVIHQ--ELFAP 629
Query: 748 CHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPAN-CPLSC 806
CH + P + + C +D C G LC L+ YA C + G+ + D+R+ + C + C
Sbjct: 630 CHIYISPGLYYQLCRHDACKCGSS--CLCNALAHYAYLCGQHGVPI-DFRTQISFCAVVC 686
Query: 807 PANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPG--FVASGGACVPASSCGCTF 864
Y C C SC ++P CS C EGC C G + + CVP C C +
Sbjct: 687 QKGMLYHHCSSFCLHSCISLSSPEQCSD-DCAEGCNCPEGKFYEDTLNFCVPIFHCRCHY 745
Query: 865 QGLQLAPGQ--------------EVWADELCQRRC------------------------- 885
+G PG+ V DEL
Sbjct: 746 RGSVYQPGELIPTPSGLCQCSNGTVKCDELATPSAVHICPEGKEYFDCRFPDPELPAGGV 805
Query: 886 ----TCNGATHQVTCRDKQSCPAGERCS---VQNGLLGC--YPDRFGTCQGSGDPHYVSF 936
TC TC C +G C+ + G+ C YP C GD HY SF
Sbjct: 806 NCETTCANLAMNFTCTPSSPCISGCVCAPGVCRRGMFNCTYYPCP-AVCTIYGDRHYYSF 864
Query: 937 DGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVR 996
DG +D++ C L+ S + V+ +N+ + +++V + ++ +
Sbjct: 865 DGLEYDYISDCQVFLIKSADDSD----ISVIAQNKKCFDNDIVCSKSVLISVGDTEIYLN 920
Query: 997 REYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVR-TDFGLTVTYDWNARVTAKVPSS 1055
Q Q F Q+++ G VV + +T+ +D + KV
Sbjct: 921 DTPYKQK------QSGFFLENKSTYQLWKAGYYIVVYFPEKDITILWDRKTTIHIKVGPQ 974
Query: 1056 YAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSL 1115
+ L GLCGNF+ ++D+ + NA FG+SW G C D
Sbjct: 975 WKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSW-----------ALGQCESPDET 1023
Query: 1116 V----AQQLQ---SKNECGILADPKGPFRECHSKLDPQGAVRDCVYD--RCLLPGQSGPL 1166
+ A Q + +K EC IL F C + +D ++C D C L G L
Sbjct: 1024 IKPCEAHQNKFPYAKKECSILY--SDIFASCRNVIDVTSFAKNCHEDTCNCNLGGDCECL 1081
Query: 1167 CDALATYAAACQAAGATVHPWRSEELCPLSCPPHSH------YEACSYG 1209
C ++A YA C G ++H WRS +C L C ++ Y SYG
Sbjct: 1082 CTSIAAYAYKCCQEGISIH-WRSSTVCSLDCEYYNEGLGEGPYMLASYG 1129
Score = 153 bits (386), Expect = 1e-36
Identities = 126/472 (26%), Positives = 187/472 (39%), Gaps = 46/472 (9%)
Query: 881 CQRRCTCNGA--THQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDG 938
C C NGA + TC + G RC + + R G C+ G H+ +FDG
Sbjct: 22 CPYECL-NGAFCSKTGTCDCQIFQALGTRCQIIPNMGN---GRDGICKTWGQYHFETFDG 77
Query: 939 RRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHR--GSQTVSYTRAVRVEARGVKVAVR 996
+ F G C+Y+ CG P + V V N + GS Y + ++ +
Sbjct: 78 IYYYFPGNCSYIFAKDCGDLE--PRYTVWVHNSPKCLGSVYSCYRSISLFFSNQEEIRI- 134
Query: 997 REYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSY 1056
Y ++ + + LP GQ+ + + +V+T FG ++ +D + + K+ +
Sbjct: 135 --YGHEIKKNGISLTLP--QTIGQIFIEKLADYILVKTTFGFSLAWDGISGIYLKLSEDH 190
Query: 1057 AEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPG--CGATEPGDCPKLDS 1114
CGLCGN+N +DD + + F NSW +T C T P D P S
Sbjct: 191 KGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVLT-PSDFPNPCS 249
Query: 1115 LVAQQLQS-KNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATY 1173
++ +C IL + PF CH +DP + CV D C C A Y
Sbjct: 250 SGMPAFEAIFFKCQILL--QFPFLSCHEYIDPYLYIASCVNDLCKTDDDE-TYCRAATEY 306
Query: 1174 AAACQAAGATVHPWRSE-ELCPLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCV 1232
A AC AG + WR + C C + C CP +C G C +GC
Sbjct: 307 ARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTCTFEKQCLGSNLHCLDGCY 366
Query: 1233 CDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGP 1292
C +G + +C+ L +C C G + G C C C GG+ +C C
Sbjct: 367 CPDGLVMDNGTCISLENCPCGFHGLAYSVGSKI--EQECTE-CVC-VGGVWNCTEQDC-- 420
Query: 1293 HEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCG 1344
C GD H+TTFDGR + F+G C Y+L + G
Sbjct: 421 -----------------PVQCSVVGDSHFTTFDGRHYSFIGMCQYILVKGTG 455
Score = 85.9 bits (211), Expect = 3e-16
Identities = 98/406 (24%), Positives = 143/406 (35%), Gaps = 47/406 (11%)
Query: 525 CVAESTAVCRAQ--GDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRG 582
C E CR + TFDG + SY +V + E + A +
Sbjct: 1431 CCPEWECPCRCSMLSELSIITFDGNNAALYSMASYILVRIPGE--IIVAHIEKCSMNQAP 1488
Query: 583 SRRVSYVGL--VTVRAYSHSVSLTR----GEVGFVLVDNQRSRLPVSLSEGRLRVYQSGP 636
S R+S + + V H + + R EV ++V P+ S L + SG
Sbjct: 1489 SGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVV-------PLPFSSQELSIEDSGS 1541
Query: 637 RAVVELVFGLVVTYDW---DCQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAPD 693
V+ GL++ + + GLCG N DP DD +G + +
Sbjct: 1542 MYVITTPAGLIIKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTIITN 1601
Query: 694 AVE---FASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHD 750
+ F SW+++ + NC Q R+ F CHD
Sbjct: 1602 MEDIGLFIESWEIEKSFEVTMRRPVRNCTEHDCSQCIDLLNRRI----------FIPCHD 1651
Query: 751 TLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSCPANS 810
+ P F E+ + C LSAY C + I + WR+P C LSCP
Sbjct: 1652 KVSPEDFCEKMWINYTYFWNYE---CDALSAYVALCNKFDICI-QWRTPDYCSLSCPEGK 1707
Query: 811 RYELCGPACPT-SCNGAAAPSNCSGRPCVEGCVCLPGFV---ASGGACVPASSCGCTFQG 866
Y+ C C +C + S E CVC G V C+P C CT
Sbjct: 1708 EYQPCVRPCEARTCLNQWFYGHTSCLNLREDCVCKVGTVLHRPHSAQCIPEKECACTDSE 1767
Query: 867 LQLAPGQEVW---ADELCQRRCTCNGATHQV--TCRDKQSCPAGER 907
Q E+W DE +C NG+ + C D++ P ER
Sbjct: 1768 DQPRTAGEIWNGGIDECTLYKCLENGSIIPIEPDC-DEEPTPVCER 1812
Score = 79.0 bits (193), Expect = 3e-14
Identities = 95/400 (23%), Positives = 146/400 (36%), Gaps = 56/400 (14%)
Query: 925 CQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAV 984
C + ++FDG +Y+LV G+ + + G + + +
Sbjct: 1441 CSMLSELSIITFDGNNAALYSMASYILVRIPGEIIVAHIEKCSMNQAPSGRISGLCFKKL 1500
Query: 985 RVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDW 1044
V K+ V R +V VD ++ LPF + + ++ G V+ T GL + +
Sbjct: 1501 NVTTPIHKIIVNR-LARKVEVDSIVVPLPFSSQELSIE--DSGSMYVITTPAGLIIKW-- 1555
Query: 1045 NARVTAKVP---------SSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFG---NS 1092
+ +T + SSY E LCG+C N DP DDL ++ G N G S
Sbjct: 1556 -SHLTGIIDIHFGFRFNLSSYTEGLCGIC---NEDPDDDLRMQNGTIITNMEDIGLFIES 1611
Query: 1093 WQEET-------RPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDP 1145
W+ E RP TE DC + L+ +++ F CH K+ P
Sbjct: 1612 WEIEKSFEVTMRRPVRNCTEH-DCSQCIDLLNRRI---------------FIPCHDKVSP 1655
Query: 1146 QGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEA 1205
+ + CDAL+ Y A C + WR+ + C LSCP Y+
Sbjct: 1656 EDFCEKMWINYTYFWNYE---CDALSAYVALCNKFDICIQ-WRTPDYCSLSCPEGKEYQP 1711
Query: 1206 CSYGCPL-SCGDLPVPGGCGS-ECHEGCVCDEGFAL---SGESCLPLASCGCV-HQGTYH 1259
C C +C + G E CVC G L C+P C C +
Sbjct: 1712 CVRPCEARTCLNQWFYGHTSCLNLREDCVCKVGTVLHRPHSAQCIPEKECACTDSEDQPR 1771
Query: 1260 PPGQTFYPGPGCDSLCHCQEGGLVSCESSSCG--PHEACQ 1297
G+ + G +L C E G + C P C+
Sbjct: 1772 TAGEIWNGGIDECTLYKCLENGSIIPIEPDCDEEPTPVCE 1811
>gi|239750386 PREDICTED: chromosome 12 open reading frame 64 [Homo
sapiens]
Length = 2250
Score = 268 bits (684), Expect = 4e-71
Identities = 239/953 (25%), Positives = 385/953 (40%), Gaps = 146/953 (15%)
Query: 511 AAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLP 570
A G RCQ++ +C+ G H+ TFDG Y G CSY + C D P
Sbjct: 45 ALGTRCQIIPNMGN---GRDGICKTWGQYHFETFDGIYYYFPGNCSYIFAKDCG--DLEP 99
Query: 571 AFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSL---TRGEVGFVLVDNQRSRLPVSLSE- 626
++V N + L +V + S+SL + E+ + +++ + ++L +
Sbjct: 100 RYTVWVHNSPKC--------LGSVYSCYRSISLFFSNQEEIRIYGHEIKKNGISLTLPQT 151
Query: 627 -GRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLT 685
G++ + + +V+ FG + +D + L L + + CGLCGNYN +DDF+
Sbjct: 152 IGQIFIEKLADYILVKTTFGFSLAWDGISGIYLKLSEDHKGKSCGLCGNYNDIQSDDFII 211
Query: 686 PDGALAPDAVEFASSWKLDDGD----YLCEDGCQNNCPACTPG-QAQHYEGDRLCGMLTK 740
D FA+SW + D L N C + P +A ++ C +L
Sbjct: 212 LQEDYTEDIAMFANSWSVQTPDDTKCVLTPSDFPNPCSSGMPAFEAIFFK----CQIL-- 265
Query: 741 LDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRS-- 798
L PF CH+ +DP ++ CV DLC + + CR + YA+AC G + DWR
Sbjct: 266 LQFPFLSCHEYIDPYLYIASCVNDLCKTDDDE-TYCRAATEYARACSHAGYPIQDWRDDF 324
Query: 799 PANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGR--PCVEGCVCLPGFVASGGACVP 856
PA C C + + C CP +C C G C++GC C G V G C+
Sbjct: 325 PA-CTDKCDDSFVHRDCISCCPPTC---TFEKQCLGSNLHCLDGCYCPDGLVMDNGTCIS 380
Query: 857 ASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLG 916
+C C F GL + G ++ ++ C C C G T +Q CP +CSV
Sbjct: 381 LENCPCGFHGLAYSVGSKI--EQEC-TECVCVGGVWNCT---EQDCPV--QCSV------ 426
Query: 917 CYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQ 976
GD H+ +FDGR + F+G C Y+LV G++ + ++ G
Sbjct: 427 -----------VGDSHFTTFDGRHYSFIGMCQYILVKGTGKDKFTITLQKAPCEQNLGLV 475
Query: 977 TVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQA--ADGQVQV-FRQGRDAVVR 1033
+ + + +V + R GQ+L P Q +G V++ +++
Sbjct: 476 CLQSITLILEDDFNKQVTLGR--GGQILTS------PNQGFNLNGIVEIQTLSSLFILLK 527
Query: 1034 TDFGLTVTYDWNA-RVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNS 1092
T FGL + + + R+ ++ S++ GLCG FNG+ DD G N+
Sbjct: 528 TTFGLKILFAIDGERIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEGTPQLHANA 587
Query: 1093 WQEETRPGCGATEPGDCPKLD--SLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVR 1150
W+ + C A P P +D ++ Q + C ++ F CH + P +
Sbjct: 588 WRVSST--CFA--PVHVPVVDPCNINQQNIGYAAHCDVIHQEL--FAPCHIYISPGLYYQ 641
Query: 1151 DCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGC 1210
C +D C S LC+ALA YA C G + C + C Y CS C
Sbjct: 642 LCRHDACKC--GSSCLCNALAHYAYLCGQHGVPIDFRTQISFCAVVCQKGMLYHHCSSFC 699
Query: 1211 PLSCGDLPVPGGCGSECHEGCVCDEG--FALSGESCLPLASCGCVHQGTYHPPGQTFYPG 1268
SC L P C +C EGC C EG + + C+P+ C C ++G+ + PG+
Sbjct: 700 LHSCISLSSPEQCSDDCAEGCNCPEGKFYEDTLNFCVPIFHCRCHYRGSVYQPGELI--- 756
Query: 1269 PGCDSLCHCQEG----------------------------------GLVSCES--SSCGP 1292
P LC C G G V+CE+ ++
Sbjct: 757 PTPSGLCQCSNGTVKCDELATPSAVHICPEGKEYFDCRFPDPELPAGGVNCETTCANLAM 816
Query: 1293 HEACQPSGGSL-GCVAVGS---------------STCQASGDPHYTTFDGRRFDFMGTCV 1336
+ C PS + GCV + C GD HY +FDG +D++ C
Sbjct: 817 NFTCTPSSPCISGCVCAPGVCRRGMFNCTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQ 876
Query: 1337 YVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWK 1389
L ++ +V+ +N + + ++ + + V + + L +K
Sbjct: 877 VFLIKSADDSD----ISVIAQNKKCFDNDIVCSKSVLISVGDTEIYLNDTPYK 925
Score = 201 bits (512), Expect = 3e-51
Identities = 195/769 (25%), Positives = 303/769 (39%), Gaps = 120/769 (15%)
Query: 516 CQVVGGKAGCVAESTAV-CRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSV 574
C VGG C + V C GD H+TTFDGR Y +G C Y +V+ +D
Sbjct: 406 CVCVGGVWNCTEQDCPVQCSVVGDSHFTTFDGRHYSFIGMCQYILVKGTGKDKFTITLQK 465
Query: 575 EAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVD-NQRSRLPVSLSEGRLRVYQ 633
++ G + + L+ ++ V+L RG G +L NQ L + L
Sbjct: 466 APCEQNLGLVCLQSITLILEDDFNKQVTLGRG--GQILTSPNQGFNLNGIVEIQTL---- 519
Query: 634 SGPRAVVELVFGLVVTYDWDCQ-LALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAP 692
S +++ FGL + + D + + + L + ++ + GLCG +NG+ DDFL+P G +
Sbjct: 520 SSLFILLKTTFGLKILFAIDGERIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEG 579
Query: 693 DAVEFASSWKLDDGDYL-----CEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAV 747
A++W++ + D C N G A H C ++ + FA
Sbjct: 580 TPQLHANAWRVSSTCFAPVHVPVVDPCNINQQNI--GYAAH------CDVIHQ--ELFAP 629
Query: 748 CHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPAN-CPLSC 806
CH + P + + C +D C G LC L+ YA C + G+ + D+R+ + C + C
Sbjct: 630 CHIYISPGLYYQLCRHDACKCGSS--CLCNALAHYAYLCGQHGVPI-DFRTQISFCAVVC 686
Query: 807 PANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPG--FVASGGACVPASSCGCTF 864
Y C C SC ++P CS C EGC C G + + CVP C C +
Sbjct: 687 QKGMLYHHCSSFCLHSCISLSSPEQCSD-DCAEGCNCPEGKFYEDTLNFCVPIFHCRCHY 745
Query: 865 QGLQLAPGQ--------------EVWADELCQRRC------------------------- 885
+G PG+ V DEL
Sbjct: 746 RGSVYQPGELIPTPSGLCQCSNGTVKCDELATPSAVHICPEGKEYFDCRFPDPELPAGGV 805
Query: 886 ----TCNGATHQVTCRDKQSCPAGERCS---VQNGLLGC--YPDRFGTCQGSGDPHYVSF 936
TC TC C +G C+ + G+ C YP C GD HY SF
Sbjct: 806 NCETTCANLAMNFTCTPSSPCISGCVCAPGVCRRGMFNCTYYPCP-AVCTIYGDRHYYSF 864
Query: 937 DGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVR 996
DG +D++ C L+ S + V+ +N+ + +++V + ++ +
Sbjct: 865 DGLEYDYISDCQVFLIKSADDSD----ISVIAQNKKCFDNDIVCSKSVLISVGDTEIYLN 920
Query: 997 REYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVR-TDFGLTVTYDWNARVTAKVPSS 1055
Q Q F Q+++ G VV + +T+ +D + KV
Sbjct: 921 DTPYKQK------QSGFFLENKSTYQLWKAGYYIVVYFPEKDITILWDRKTTIHIKVGPQ 974
Query: 1056 YAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSL 1115
+ L GLCGNF+ ++D+ + NA FG+SW G C D
Sbjct: 975 WKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSW-----------ALGQCESPDET 1023
Query: 1116 V----AQQLQ---SKNECGILADPKGPFRECHSKLDPQGAVRDCVYD--RCLLPGQSGPL 1166
+ A Q + +K EC IL F C + +D ++C D C L G L
Sbjct: 1024 IKPCEAHQNKFPYAKKECSILY--SDIFASCRNVIDVTSFAKNCHEDTCNCNLGGDCECL 1081
Query: 1167 CDALATYAAACQAAGATVHPWRSEELCPLSCPPHSH------YEACSYG 1209
C ++A YA C G ++H WRS +C L C ++ Y SYG
Sbjct: 1082 CTSIAAYAYKCCQEGISIH-WRSSTVCSLDCEYYNEGLGEGPYMLASYG 1129
Score = 153 bits (386), Expect = 1e-36
Identities = 126/472 (26%), Positives = 187/472 (39%), Gaps = 46/472 (9%)
Query: 881 CQRRCTCNGA--THQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDG 938
C C NGA + TC + G RC + + R G C+ G H+ +FDG
Sbjct: 22 CPYECL-NGAFCSKTGTCDCQIFQALGTRCQIIPNMGN---GRDGICKTWGQYHFETFDG 77
Query: 939 RRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHR--GSQTVSYTRAVRVEARGVKVAVR 996
+ F G C+Y+ CG P + V V N + GS Y + ++ +
Sbjct: 78 IYYYFPGNCSYIFAKDCGDLE--PRYTVWVHNSPKCLGSVYSCYRSISLFFSNQEEIRI- 134
Query: 997 REYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSY 1056
Y ++ + + LP GQ+ + + +V+T FG ++ +D + + K+ +
Sbjct: 135 --YGHEIKKNGISLTLP--QTIGQIFIEKLADYILVKTTFGFSLAWDGISGIYLKLSEDH 190
Query: 1057 AEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPG--CGATEPGDCPKLDS 1114
CGLCGN+N +DD + + F NSW +T C T P D P S
Sbjct: 191 KGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVLT-PSDFPNPCS 249
Query: 1115 LVAQQLQS-KNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATY 1173
++ +C IL + PF CH +DP + CV D C C A Y
Sbjct: 250 SGMPAFEAIFFKCQILL--QFPFLSCHEYIDPYLYIASCVNDLCKTDDDE-TYCRAATEY 306
Query: 1174 AAACQAAGATVHPWRSE-ELCPLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCV 1232
A AC AG + WR + C C + C CP +C G C +GC
Sbjct: 307 ARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTCTFEKQCLGSNLHCLDGCY 366
Query: 1233 CDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGP 1292
C +G + +C+ L +C C G + G C C C GG+ +C C
Sbjct: 367 CPDGLVMDNGTCISLENCPCGFHGLAYSVGSKI--EQECTE-CVC-VGGVWNCTEQDC-- 420
Query: 1293 HEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCG 1344
C GD H+TTFDGR + F+G C Y+L + G
Sbjct: 421 -----------------PVQCSVVGDSHFTTFDGRHYSFIGMCQYILVKGTG 455
Score = 85.5 bits (210), Expect = 3e-16
Identities = 97/406 (23%), Positives = 143/406 (35%), Gaps = 47/406 (11%)
Query: 525 CVAESTAVCRAQ--GDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRG 582
C E CR + TFDG + SY +V + E + A +
Sbjct: 1431 CCPEWECPCRCSMLSELSIITFDGNNAALYSMASYILVRIPGE--IIVAHIEKCSMNQAP 1488
Query: 583 SRRVSYVGL--VTVRAYSHSVSLTR----GEVGFVLVDNQRSRLPVSLSEGRLRVYQSGP 636
S R+S + + V H + + R EV ++V P+ S L + SG
Sbjct: 1489 SGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVV-------PLPFSSQELSIEDSGS 1541
Query: 637 RAVVELVFGLVVTYDW---DCQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAPD 693
V+ GL++ + + GLCG N DP DD +G + +
Sbjct: 1542 MYVITTPAGLIIKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTIITN 1601
Query: 694 AVE---FASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHD 750
+ F SW+++ + NC Q R+ F CHD
Sbjct: 1602 MEDIGLFIESWEIEKSFEVTMRRPVRNCTEHDCSQCIDLLNRRI----------FIPCHD 1651
Query: 751 TLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSCPANS 810
+ P F E+ + C LSAY C + I + WR+P C LSCP
Sbjct: 1652 KVSPEDFCEKMWINYTYFWNYE---CDALSAYVALCNKFDICI-QWRTPDYCSLSCPEGK 1707
Query: 811 RYELCGPACPT-SCNGAAAPSNCSGRPCVEGCVCLPGFV---ASGGACVPASSCGCTFQG 866
Y+ C C +C + S E CVC G + C+P C CT
Sbjct: 1708 EYQPCVRPCEARTCLNQWFYGHTSCLNLREDCVCKVGTILHRPHSAQCIPEKECACTDSE 1767
Query: 867 LQLAPGQEVW---ADELCQRRCTCNGATHQV--TCRDKQSCPAGER 907
Q E+W DE +C NG+ + C D++ P ER
Sbjct: 1768 DQPRTAGEIWNGGIDECTLYKCLENGSIIPIEPDC-DEEPTPVCER 1812
Score = 78.6 bits (192), Expect = 4e-14
Identities = 95/400 (23%), Positives = 146/400 (36%), Gaps = 56/400 (14%)
Query: 925 CQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAV 984
C + ++FDG +Y+LV G+ + + G + + +
Sbjct: 1441 CSMLSELSIITFDGNNAALYSMASYILVRIPGEIIVAHIEKCSMNQAPSGRISGLCFKKL 1500
Query: 985 RVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDW 1044
V K+ V R +V VD ++ LPF + + ++ G V+ T GL + +
Sbjct: 1501 NVTTPIHKIIVNR-LARKVEVDSIVVPLPFSSQELSIE--DSGSMYVITTPAGLIIKW-- 1555
Query: 1045 NARVTAKVP---------SSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFG---NS 1092
+ +T + SSY E LCG+C N DP DDL ++ G N G S
Sbjct: 1556 -SHLTGIIDIHFGFRFNLSSYTEGLCGIC---NEDPDDDLRMQNGTIITNMEDIGLFIES 1611
Query: 1093 WQEET-------RPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDP 1145
W+ E RP TE DC + L+ +++ F CH K+ P
Sbjct: 1612 WEIEKSFEVTMRRPVRNCTEH-DCSQCIDLLNRRI---------------FIPCHDKVSP 1655
Query: 1146 QGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEA 1205
+ + CDAL+ Y A C + WR+ + C LSCP Y+
Sbjct: 1656 EDFCEKMWINYTYFWNYE---CDALSAYVALCNKFDICIQ-WRTPDYCSLSCPEGKEYQP 1711
Query: 1206 CSYGCPL-SCGDLPVPGGCGS-ECHEGCVCDEGFAL---SGESCLPLASCGCV-HQGTYH 1259
C C +C + G E CVC G L C+P C C +
Sbjct: 1712 CVRPCEARTCLNQWFYGHTSCLNLREDCVCKVGTILHRPHSAQCIPEKECACTDSEDQPR 1771
Query: 1260 PPGQTFYPGPGCDSLCHCQEGGLVSCESSSCG--PHEACQ 1297
G+ + G +L C E G + C P C+
Sbjct: 1772 TAGEIWNGGIDECTLYKCLENGSIIPIEPDCDEEPTPVCE 1811
>gi|239744688 PREDICTED: hypothetical protein LOC283310 [Homo sapiens]
Length = 2250
Score = 268 bits (684), Expect = 4e-71
Identities = 239/953 (25%), Positives = 385/953 (40%), Gaps = 146/953 (15%)
Query: 511 AAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLP 570
A G RCQ++ +C+ G H+ TFDG Y G CSY + C D P
Sbjct: 45 ALGTRCQIIPNMGN---GRDGICKTWGQYHFETFDGIYYYFPGNCSYIFAKDCG--DLEP 99
Query: 571 AFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSL---TRGEVGFVLVDNQRSRLPVSLSE- 626
++V N + L +V + S+SL + E+ + +++ + ++L +
Sbjct: 100 RYTVWVHNSPKC--------LGSVYSCYRSISLFFSNQEEIRIYGHEIKKNGISLTLPQT 151
Query: 627 -GRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLT 685
G++ + + +V+ FG + +D + L L + + CGLCGNYN +DDF+
Sbjct: 152 IGQIFIEKLADYILVKTTFGFSLAWDGISGIYLKLSEDHKGKSCGLCGNYNDIQSDDFII 211
Query: 686 PDGALAPDAVEFASSWKLDDGD----YLCEDGCQNNCPACTPG-QAQHYEGDRLCGMLTK 740
D FA+SW + D L N C + P +A ++ C +L
Sbjct: 212 LQEDYTEDIAMFANSWSVQTPDDTKCVLTPSDFPNPCSSGMPAFEAIFFK----CQIL-- 265
Query: 741 LDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRS-- 798
L PF CH+ +DP ++ CV DLC + + CR + YA+AC G + DWR
Sbjct: 266 LQFPFLSCHEYIDPYLYIASCVNDLCKTDDDE-TYCRAATEYARACSHAGYPIQDWRDDF 324
Query: 799 PANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGR--PCVEGCVCLPGFVASGGACVP 856
PA C C + + C CP +C C G C++GC C G V G C+
Sbjct: 325 PA-CTDKCDDSFVHRDCISCCPPTC---TFEKQCLGSNLHCLDGCYCPDGLVMDNGTCIS 380
Query: 857 ASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLG 916
+C C F GL + G ++ ++ C C C G T +Q CP +CSV
Sbjct: 381 LENCPCGFHGLAYSVGSKI--EQEC-TECVCVGGVWNCT---EQDCPV--QCSV------ 426
Query: 917 CYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQ 976
GD H+ +FDGR + F+G C Y+LV G++ + ++ G
Sbjct: 427 -----------VGDSHFTTFDGRHYSFIGMCQYILVKGTGKDKFTITLQKAPCEQNLGLV 475
Query: 977 TVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQA--ADGQVQV-FRQGRDAVVR 1033
+ + + +V + R GQ+L P Q +G V++ +++
Sbjct: 476 CLQSITLILEDDFNKQVTLGR--GGQILTS------PNQGFNLNGIVEIQTLSSLFILLK 527
Query: 1034 TDFGLTVTYDWNA-RVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNS 1092
T FGL + + + R+ ++ S++ GLCG FNG+ DD G N+
Sbjct: 528 TTFGLKILFAIDGERIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEGTPQLHANA 587
Query: 1093 WQEETRPGCGATEPGDCPKLD--SLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVR 1150
W+ + C A P P +D ++ Q + C ++ F CH + P +
Sbjct: 588 WRVSST--CFA--PVHVPVVDPCNINQQNIGYAAHCDVIHQEL--FAPCHIYISPGLYYQ 641
Query: 1151 DCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGC 1210
C +D C S LC+ALA YA C G + C + C Y CS C
Sbjct: 642 LCRHDACKC--GSSCLCNALAHYAYLCGQHGVPIDFRTQISFCAVVCQKGMLYHHCSSFC 699
Query: 1211 PLSCGDLPVPGGCGSECHEGCVCDEG--FALSGESCLPLASCGCVHQGTYHPPGQTFYPG 1268
SC L P C +C EGC C EG + + C+P+ C C ++G+ + PG+
Sbjct: 700 LHSCISLSSPEQCSDDCAEGCNCPEGKFYEDTLNFCVPIFHCRCHYRGSVYQPGELI--- 756
Query: 1269 PGCDSLCHCQEG----------------------------------GLVSCES--SSCGP 1292
P LC C G G V+CE+ ++
Sbjct: 757 PTPSGLCQCSNGTVKCDELATPSAVHICPEGKEYFDCRFPDPELPAGGVNCETTCANLAM 816
Query: 1293 HEACQPSGGSL-GCVAVGS---------------STCQASGDPHYTTFDGRRFDFMGTCV 1336
+ C PS + GCV + C GD HY +FDG +D++ C
Sbjct: 817 NFTCTPSSPCISGCVCAPGVCRRGMFNCTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQ 876
Query: 1337 YVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWK 1389
L ++ +V+ +N + + ++ + + V + + L +K
Sbjct: 877 VFLIKSADDSD----ISVIAQNKKCFDNDIVCSKSVLISVGDTEIYLNDTPYK 925
Score = 201 bits (512), Expect = 3e-51
Identities = 195/769 (25%), Positives = 303/769 (39%), Gaps = 120/769 (15%)
Query: 516 CQVVGGKAGCVAESTAV-CRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSV 574
C VGG C + V C GD H+TTFDGR Y +G C Y +V+ +D
Sbjct: 406 CVCVGGVWNCTEQDCPVQCSVVGDSHFTTFDGRHYSFIGMCQYILVKGTGKDKFTITLQK 465
Query: 575 EAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVD-NQRSRLPVSLSEGRLRVYQ 633
++ G + + L+ ++ V+L RG G +L NQ L + L
Sbjct: 466 APCEQNLGLVCLQSITLILEDDFNKQVTLGRG--GQILTSPNQGFNLNGIVEIQTL---- 519
Query: 634 SGPRAVVELVFGLVVTYDWDCQ-LALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAP 692
S +++ FGL + + D + + + L + ++ + GLCG +NG+ DDFL+P G +
Sbjct: 520 SSLFILLKTTFGLKILFAIDGERIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEG 579
Query: 693 DAVEFASSWKLDDGDYL-----CEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAV 747
A++W++ + D C N G A H C ++ + FA
Sbjct: 580 TPQLHANAWRVSSTCFAPVHVPVVDPCNINQQNI--GYAAH------CDVIHQ--ELFAP 629
Query: 748 CHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPAN-CPLSC 806
CH + P + + C +D C G LC L+ YA C + G+ + D+R+ + C + C
Sbjct: 630 CHIYISPGLYYQLCRHDACKCGSS--CLCNALAHYAYLCGQHGVPI-DFRTQISFCAVVC 686
Query: 807 PANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPG--FVASGGACVPASSCGCTF 864
Y C C SC ++P CS C EGC C G + + CVP C C +
Sbjct: 687 QKGMLYHHCSSFCLHSCISLSSPEQCSD-DCAEGCNCPEGKFYEDTLNFCVPIFHCRCHY 745
Query: 865 QGLQLAPGQ--------------EVWADELCQRRC------------------------- 885
+G PG+ V DEL
Sbjct: 746 RGSVYQPGELIPTPSGLCQCSNGTVKCDELATPSAVHICPEGKEYFDCRFPDPELPAGGV 805
Query: 886 ----TCNGATHQVTCRDKQSCPAGERCS---VQNGLLGC--YPDRFGTCQGSGDPHYVSF 936
TC TC C +G C+ + G+ C YP C GD HY SF
Sbjct: 806 NCETTCANLAMNFTCTPSSPCISGCVCAPGVCRRGMFNCTYYPCP-AVCTIYGDRHYYSF 864
Query: 937 DGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVR 996
DG +D++ C L+ S + V+ +N+ + +++V + ++ +
Sbjct: 865 DGLEYDYISDCQVFLIKSADDSD----ISVIAQNKKCFDNDIVCSKSVLISVGDTEIYLN 920
Query: 997 REYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVR-TDFGLTVTYDWNARVTAKVPSS 1055
Q Q F Q+++ G VV + +T+ +D + KV
Sbjct: 921 DTPYKQK------QSGFFLENKSTYQLWKAGYYIVVYFPEKDITILWDRKTTIHIKVGPQ 974
Query: 1056 YAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSL 1115
+ L GLCGNF+ ++D+ + NA FG+SW G C D
Sbjct: 975 WKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSW-----------ALGQCESPDET 1023
Query: 1116 V----AQQLQ---SKNECGILADPKGPFRECHSKLDPQGAVRDCVYD--RCLLPGQSGPL 1166
+ A Q + +K EC IL F C + +D ++C D C L G L
Sbjct: 1024 IKPCEAHQNKFPYAKKECSILY--SDIFASCRNVIDVTSFAKNCHEDTCNCNLGGDCECL 1081
Query: 1167 CDALATYAAACQAAGATVHPWRSEELCPLSCPPHSH------YEACSYG 1209
C ++A YA C G ++H WRS +C L C ++ Y SYG
Sbjct: 1082 CTSIAAYAYKCCQEGISIH-WRSSTVCSLDCEYYNEGLGEGPYMLASYG 1129
Score = 153 bits (386), Expect = 1e-36
Identities = 126/472 (26%), Positives = 187/472 (39%), Gaps = 46/472 (9%)
Query: 881 CQRRCTCNGA--THQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDG 938
C C NGA + TC + G RC + + R G C+ G H+ +FDG
Sbjct: 22 CPYECL-NGAFCSKTGTCDCQIFQALGTRCQIIPNMGN---GRDGICKTWGQYHFETFDG 77
Query: 939 RRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHR--GSQTVSYTRAVRVEARGVKVAVR 996
+ F G C+Y+ CG P + V V N + GS Y + ++ +
Sbjct: 78 IYYYFPGNCSYIFAKDCGDLE--PRYTVWVHNSPKCLGSVYSCYRSISLFFSNQEEIRI- 134
Query: 997 REYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSY 1056
Y ++ + + LP GQ+ + + +V+T FG ++ +D + + K+ +
Sbjct: 135 --YGHEIKKNGISLTLP--QTIGQIFIEKLADYILVKTTFGFSLAWDGISGIYLKLSEDH 190
Query: 1057 AEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPG--CGATEPGDCPKLDS 1114
CGLCGN+N +DD + + F NSW +T C T P D P S
Sbjct: 191 KGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVLT-PSDFPNPCS 249
Query: 1115 LVAQQLQS-KNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATY 1173
++ +C IL + PF CH +DP + CV D C C A Y
Sbjct: 250 SGMPAFEAIFFKCQILL--QFPFLSCHEYIDPYLYIASCVNDLCKTDDDE-TYCRAATEY 306
Query: 1174 AAACQAAGATVHPWRSE-ELCPLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCV 1232
A AC AG + WR + C C + C CP +C G C +GC
Sbjct: 307 ARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTCTFEKQCLGSNLHCLDGCY 366
Query: 1233 CDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGP 1292
C +G + +C+ L +C C G + G C C C GG+ +C C
Sbjct: 367 CPDGLVMDNGTCISLENCPCGFHGLAYSVGSKI--EQECTE-CVC-VGGVWNCTEQDC-- 420
Query: 1293 HEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCG 1344
C GD H+TTFDGR + F+G C Y+L + G
Sbjct: 421 -----------------PVQCSVVGDSHFTTFDGRHYSFIGMCQYILVKGTG 455
Score = 85.5 bits (210), Expect = 3e-16
Identities = 97/406 (23%), Positives = 143/406 (35%), Gaps = 47/406 (11%)
Query: 525 CVAESTAVCRAQ--GDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRG 582
C E CR + TFDG + SY +V + E + A +
Sbjct: 1431 CCPEWECPCRCSMLSELSIITFDGNNAALYSMASYILVRIPGE--IIVAHIEKCSMNQAP 1488
Query: 583 SRRVSYVGL--VTVRAYSHSVSLTR----GEVGFVLVDNQRSRLPVSLSEGRLRVYQSGP 636
S R+S + + V H + + R EV ++V P+ S L + SG
Sbjct: 1489 SGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVV-------PLPFSSQELSIEDSGS 1541
Query: 637 RAVVELVFGLVVTYDW---DCQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAPD 693
V+ GL++ + + GLCG N DP DD +G + +
Sbjct: 1542 MYVITTPAGLIIKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTIITN 1601
Query: 694 AVE---FASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHD 750
+ F SW+++ + NC Q R+ F CHD
Sbjct: 1602 MEDIGLFIESWEIEKSFEVTMRRPVRNCTEHDCSQCIDLLNRRI----------FIPCHD 1651
Query: 751 TLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSCPANS 810
+ P F E+ + C LSAY C + I + WR+P C LSCP
Sbjct: 1652 KVSPEDFCEKMWINYTYFWNYE---CDALSAYVALCNKFDICI-QWRTPDYCSLSCPEGK 1707
Query: 811 RYELCGPACPT-SCNGAAAPSNCSGRPCVEGCVCLPGFV---ASGGACVPASSCGCTFQG 866
Y+ C C +C + S E CVC G + C+P C CT
Sbjct: 1708 EYQPCVRPCEARTCLNQWFYGHTSCLNLREDCVCKVGTILHRPHSAQCIPEKECACTDSE 1767
Query: 867 LQLAPGQEVW---ADELCQRRCTCNGATHQV--TCRDKQSCPAGER 907
Q E+W DE +C NG+ + C D++ P ER
Sbjct: 1768 DQPRTAGEIWNGGIDECTLYKCLENGSIIPIEPDC-DEEPTPVCER 1812
Score = 78.6 bits (192), Expect = 4e-14
Identities = 95/400 (23%), Positives = 146/400 (36%), Gaps = 56/400 (14%)
Query: 925 CQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAV 984
C + ++FDG +Y+LV G+ + + G + + +
Sbjct: 1441 CSMLSELSIITFDGNNAALYSMASYILVRIPGEIIVAHIEKCSMNQAPSGRISGLCFKKL 1500
Query: 985 RVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDW 1044
V K+ V R +V VD ++ LPF + + ++ G V+ T GL + +
Sbjct: 1501 NVTTPIHKIIVNR-LARKVEVDSIVVPLPFSSQELSIE--DSGSMYVITTPAGLIIKW-- 1555
Query: 1045 NARVTAKVP---------SSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFG---NS 1092
+ +T + SSY E LCG+C N DP DDL ++ G N G S
Sbjct: 1556 -SHLTGIIDIHFGFRFNLSSYTEGLCGIC---NEDPDDDLRMQNGTIITNMEDIGLFIES 1611
Query: 1093 WQEET-------RPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDP 1145
W+ E RP TE DC + L+ +++ F CH K+ P
Sbjct: 1612 WEIEKSFEVTMRRPVRNCTEH-DCSQCIDLLNRRI---------------FIPCHDKVSP 1655
Query: 1146 QGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEA 1205
+ + CDAL+ Y A C + WR+ + C LSCP Y+
Sbjct: 1656 EDFCEKMWINYTYFWNYE---CDALSAYVALCNKFDICIQ-WRTPDYCSLSCPEGKEYQP 1711
Query: 1206 CSYGCPL-SCGDLPVPGGCGS-ECHEGCVCDEGFAL---SGESCLPLASCGCV-HQGTYH 1259
C C +C + G E CVC G L C+P C C +
Sbjct: 1712 CVRPCEARTCLNQWFYGHTSCLNLREDCVCKVGTILHRPHSAQCIPEKECACTDSEDQPR 1771
Query: 1260 PPGQTFYPGPGCDSLCHCQEGGLVSCESSSCG--PHEACQ 1297
G+ + G +L C E G + C P C+
Sbjct: 1772 TAGEIWNGGIDECTLYKCLENGSIIPIEPDCDEEPTPVCE 1811
>gi|151301154 mucin 6, gastric [Homo sapiens]
Length = 2439
Score = 250 bits (639), Expect = 6e-66
Identities = 217/779 (27%), Positives = 331/779 (42%), Gaps = 96/779 (12%)
Query: 533 CRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRGS--RRVSYVG 590
C G H++TFD YD GTC+Y C D P FSV+ + GS R + +G
Sbjct: 45 CSTWGAGHFSTFDHHVYDFSGTCNYIFAATCK--DAFPTFSVQLRRGPDGSISRIIVELG 102
Query: 591 LVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVTY 650
V +S+ ++G + + + L ++ +R+ +E+V+G
Sbjct: 103 ASVVTVSEAIISVK--DIGVISLPYTSNGLQITPFGQSVRLVAKQLELELEVVWGP---- 156
Query: 651 DWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLC 710
D L + + ++ Q+CGLCGN++G ++F++ +G + +FA+ KLDD +C
Sbjct: 157 --DSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFL-EPHKFAALQKLDDPGEIC 213
Query: 711 EDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVG- 769
+ P+ QAQH R+C L L P ++ PF+ C D+
Sbjct: 214 TF---QDIPSTHVRQAQHA---RICTQLLTLVAPEC----SVSKEPFVLSCQADVAAAPQ 263
Query: 770 -GERLSLCRGLSAYAQACLELGISVGDWRSPANCPLS-CPANSRYELCGPACPTSCNGAA 827
G + S C LS Y++ C +G V WRSP C + CPAN Y+ CG AC +C+
Sbjct: 264 PGPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSACVKTCSN-- 321
Query: 828 APSNCSGRPCVEGCVCLPGFV----ASGGACVPASSCGCTFQGLQLAPGQEVWADELCQR 883
P + C GC C G V ++ CVP + C C G APG+ A CQ
Sbjct: 322 -PQHSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTIA--ACQ- 377
Query: 884 RCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDF 943
TC + C ++ CP G C G +FD R + F
Sbjct: 378 --TCRCTLGRWVCTERP-CP-------------------GHCSLEGGSFVTTFDARPYRF 415
Query: 944 MGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAVRVE--ARGVKVAVRREYPG 1001
GTCTY+L+ Q+ LP L+ + + S T V V +R K+ + ++
Sbjct: 416 HGTCTYILL----QSPQLPEDGALMAVYDKSGVSHSETSLVAVVYLSRQDKIVISQDEV- 470
Query: 1002 QVLVDDVLQYLPFQAADGQVQVFRQGRDAV-VRTDFGLTVTYD----WNARVTAKVPSSY 1056
V + ++LP++ + + VFRQ + + T FGL + + A VT V +
Sbjct: 471 -VTNNGEAKWLPYKTRN--ITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVT--VGPQF 525
Query: 1057 AEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGC--GATEPGDCPKLDS 1114
GLCGNFNGD DD G A F +SW+ P T+P +L+
Sbjct: 526 RGQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWRAGNCPAALERETDPCSMSQLNK 585
Query: 1115 LVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYA 1174
+ A+ C +L F CH+ ++P + CVY C +C AL Y
Sbjct: 586 VCAE-----THCSMLLRTGTVFERCHATVNPAPFYKRCVYQACNYEETFPHICAALGDYV 640
Query: 1175 AACQAAGATVHPWRSE-ELCPLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSECH----- 1228
AC G + WRS + C + C ++ + S C +C L +ECH
Sbjct: 641 HACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLSL---SDRATECHHSAVP 697
Query: 1229 -EGCVCDEGFALSGE-SCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSC 1285
+GC C +G L+ + C+ A C C+ +G + G CHC G L SC
Sbjct: 698 VDGCNCPDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVINGI--TCHCINGRL-SC 753
Score = 168 bits (426), Expect = 3e-41
Identities = 146/500 (29%), Positives = 210/500 (42%), Gaps = 82/500 (16%)
Query: 805 SCPANSRYELC--------GPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASG-GACV 855
SC A ++ C G AC +C A C C GCVC G + G CV
Sbjct: 763 SCQAPKTFKSCSQSSENKFGAACAPTCQMLATGVACVPTKCEPGCVCAEGLYENADGQCV 822
Query: 856 PASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLL 915
P C C F G+ G E+ D C R C+C+ R + +C G C
Sbjct: 823 PPEECPCEFSGVSYPGGAELHTD--C-RTCSCS--------RGRWACQQGTHCP------ 865
Query: 916 GCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGS-CGQNAALPAFRVLVENEHRG 974
TC G+ H ++FDG+RF F G C Y+L CG N + P F++L EN G
Sbjct: 866 -------STCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPTFKILTENVICG 918
Query: 975 SQTVSYTRAVRVEARGVKVAVR-REYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVR 1033
+ V+ +RA+++ G+ V + R Y V ++ G + + D +
Sbjct: 919 NSGVTCSRAIKIFLGGLSVVLADRNYT----VTGEEPHVQLGVTPGALSLVV---DISIP 971
Query: 1034 TDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSW 1093
+ LT+ ++ + + ++ + + LCGLCGNFNG+ DD R A++ L NSW
Sbjct: 972 GRYNLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSW 1031
Query: 1094 QEETRPGCG----ATEPGDCPKLDSLVA-QQLQSKNECGILADPKGPFRECHSKLDPQGA 1148
+E P CG T+P C SL A ++ ++ +C ++ F CHSK+
Sbjct: 1032 KES--PLCGDVSFVTDP--C----SLNAFRRSWAERKCSVINSQ--TFATCHSKVYHLPY 1081
Query: 1149 VRDCVYDRCLLP--GQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEAC 1206
CV D C G LCDA+A YA AC G V WR+ CP+ C ++ +
Sbjct: 1082 YEACVRDACGCDSGGDCECLCDAVAAYAQACLDKGVCV-DWRTPAFCPIYCGFYNTHTQD 1140
Query: 1207 SYG---------C-----PLSCGDLP--VPGGCGSECHEGCVCDEGFALSGESCLPLASC 1250
+G C P C P VPG C+ C DE F C+P
Sbjct: 1141 GHGEYQYTQEANCTWHYQPCLCPSQPQSVPGSNIEGCY-NCSQDEYFDHEEGVCVP---- 1195
Query: 1251 GCVHQGTYHPPGQTFYPGPG 1270
C+ T PP P G
Sbjct: 1196 -CMPPTTPQPPTTPQLPTTG 1214
Score = 135 bits (340), Expect = 3e-31
Identities = 119/435 (27%), Positives = 177/435 (40%), Gaps = 45/435 (10%)
Query: 511 AAGQRCQVVGGKAGCVAEST-AVCRAQGDPHYTTFDGRRYDMMGTCSYTMVEL--CSEDD 567
AA Q C+ G+ C C +G TTFD R Y GTC+Y +++ ED
Sbjct: 374 AACQTCRCTLGRWVCTERPCPGHCSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDG 433
Query: 568 TLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEG 627
L A ++ H + V+ V L + + +++ EV V N +
Sbjct: 434 ALMAVYDKSGVSHSETSLVAVVYL----SRQDKIVISQDEV----VTNNGEAKWLPYKTR 485
Query: 628 RLRVY-QSGPRAVVELVFGL--VVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFL 684
+ V+ Q+ + FGL VV Q +++ +F+ Q GLCGN+NGD DDF
Sbjct: 486 NITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFT 545
Query: 685 TPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGP 744
T G A F SW+ + C + C+ Q + C ML +
Sbjct: 546 TSMGIAEGTASLFVDSWRAGN----CPAALERETDPCSMSQLNKVCAETHCSMLLRTGTV 601
Query: 745 FAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPA-NCP 803
F CH T++P PF ++CVY C +C L Y AC G+ + WRS NC
Sbjct: 602 FERCHATVNPAPFYKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCT 661
Query: 804 LSCPANSRYELCGPACPTSC---NGAAAPSNCSGRPCVEGCVCLPG-FVASGGACVPASS 859
+ C N+ + AC +C + A + S P V+GC C G ++ G CV +
Sbjct: 662 IPCTGNTTFSYNSQACERTCLSLSDRATECHHSAVP-VDGCNCPDGTYLNQKGECVRKAQ 720
Query: 860 CGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTC---RDKQSCPAGERCSVQNGLLG 916
C C +G + L ++ NG +TC + SCP Q L
Sbjct: 721 CPCILEGYKFI---------LAEQSTVING----ITCHCINGRLSCPQ----RPQMFLAS 763
Query: 917 CY-PDRFGTCQGSGD 930
C P F +C S +
Sbjct: 764 CQAPKTFKSCSQSSE 778
Score = 134 bits (338), Expect = 5e-31
Identities = 121/433 (27%), Positives = 169/433 (39%), Gaps = 55/433 (12%)
Query: 919 PDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTV 978
PD+ G C G H+ +FD +DF GTC Y+ +C A P F V + GS
Sbjct: 40 PDK-GQCSTWGAGHFSTFDHHVYDFSGTCNYIFAATC--KDAFPTFSVQLRRGPDGS--- 93
Query: 979 SYTRAVRVEARGVKVAVRREYPGQVLVDDV-LQYLPFQAADGQVQVFRQG-RDAVVRTDF 1036
+ VE V V + V D+ + LP+ + Q+ F Q R + +
Sbjct: 94 --ISRIIVELGASVVTVSEAI---ISVKDIGVISLPYTSNGLQITPFGQSVRLVAKQLEL 148
Query: 1037 GLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEE 1096
L V + ++ + V Y +CGLCGNF+G ++ + G+ F + Q+
Sbjct: 149 ELEVVWGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEF-VSEEGKFLEPHKFA-ALQKL 206
Query: 1097 TRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDR 1156
PG E + S +Q Q C L P EC +P V C D
Sbjct: 207 DDPG----EICTFQDIPSTHVRQAQHARICTQLLTLVAP--ECSVSKEP--FVLSCQADV 258
Query: 1157 CLL--PGQSGPLCDALATYAAACQAAGATVHPWRSEELCPL-SCPPHSHYEACSYGCPLS 1213
PG C L+ Y+ C G V WRS LC + CP + Y+ C C +
Sbjct: 259 AAAPQPGPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSACVKT 318
Query: 1214 CGDLPVPGGCGSECHEGCVCDEGFAL----SGESCLPLASCGCVHQGTYHPPGQTFYPGP 1269
C + C S C GC C EG L + +C+P+ C CV G + PG+
Sbjct: 319 CSN--PQHSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTI--A 374
Query: 1270 GCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRF 1329
C + C C G V C C H C G TTFD R +
Sbjct: 375 ACQT-CRCTLGRWV-CTERPCPGH-------------------CSLEGGSFVTTFDARPY 413
Query: 1330 DFMGTCVYVLAQT 1342
F GTC Y+L Q+
Sbjct: 414 RFHGTCTYILLQS 426
Score = 127 bits (320), Expect = 6e-29
Identities = 108/383 (28%), Positives = 166/383 (43%), Gaps = 64/383 (16%)
Query: 505 CEGMQCAAGQ-RCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMV-EL 562
C C+ G+ CQ G ST C G+ H TFDG+R+ G C Y + ++
Sbjct: 846 CRTCSCSRGRWACQ-----QGTHCPST--CTLYGEGHVITFDGQRFVFDGNCEYILATDV 898
Query: 563 CSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDN------Q 616
C +D+ P F + +N G+ V+ S ++ + G + VL D +
Sbjct: 899 CGVNDSQPTFKILTENVICGNSGVTC---------SRAIKIFLGGLSVVLADRNYTVTGE 949
Query: 617 RSRLPVSLSEGRLRVYQSGPRAVVELV----FGLVVTYDWDCQLALSLPARFQDQVCGLC 672
+ + ++ G L + VV++ + L + ++ + + + QD +CGLC
Sbjct: 950 EPHVQLGVTPGALSL-------VVDISIPGRYNLTLIWNRHMTILIRIARASQDPLCGLC 1002
Query: 673 GNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGD 732
GN+NG+ DDF T +A +E +SWK LC D P C+ + +
Sbjct: 1003 GNFNGNMKDDFETRSRYVASSELELVNSWKESP---LCGDVSFVTDP-CSLNAFRRSWAE 1058
Query: 733 RLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVV--GGERLSLCRGLSAYAQACLELG 790
R C ++ FA CH + P+ E CV D C GG+ LC ++AYAQACL+ G
Sbjct: 1059 RKCSVIN--SQTFATCHSKVYHLPYYEACVRDACGCDSGGDCECLCDAVAAYAQACLDKG 1116
Query: 791 ISVGDWRSPANCPLSC--------PANSRYELCGPACPTSCNGAAAPSNCSGRP------ 836
+ V DWR+PA CP+ C + Y+ A +C P C +P
Sbjct: 1117 VCV-DWRTPAFCPIYCGFYNTHTQDGHGEYQYTQEA---NCTWHYQPCLCPSQPQSVPGS 1172
Query: 837 CVEGCV-CLPG--FVASGGACVP 856
+EGC C F G CVP
Sbjct: 1173 NIEGCYNCSQDEYFDHEEGVCVP 1195
Score = 87.8 bits (216), Expect = 7e-17
Identities = 65/229 (28%), Positives = 90/229 (39%), Gaps = 40/229 (17%)
Query: 1181 GATVHPWRSEELCP-------LSCPPHSHYEACSYG--------CPLSCGDLPVPGGC-G 1224
G T H CP SC +++CS C +C L C
Sbjct: 741 GITCHCINGRLSCPQRPQMFLASCQAPKTFKSCSQSSENKFGAACAPTCQMLATGVACVP 800
Query: 1225 SECHEGCVCDEGFALSGES-CLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLV 1283
++C GCVC EG + + C+P C C G +P G + C + C C G
Sbjct: 801 TKCEPGCVCAEGLYENADGQCVPPEECPCEFSGVSYPGGAELHTD--CRT-CSCSRGRWA 857
Query: 1284 SCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLA-QT 1342
+ + C STC G+ H TFDG+RF F G C Y+LA
Sbjct: 858 CQQGTHC-------------------PSTCTLYGEGHVITFDGQRFVFDGNCEYILATDV 898
Query: 1343 CGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVT 1391
CG F +L ENV GN V+ +R I + + ++ L R + VT
Sbjct: 899 CGVNDSQPTFKILTENVICGNSGVTCSRAIKIFLGGLSVVLADRNYTVT 947
Score = 39.3 bits (90), Expect = 0.028
Identities = 15/31 (48%), Positives = 19/31 (61%)
Query: 1313 CQASGDPHYTTFDGRRFDFMGTCVYVLAQTC 1343
C G H++TFD +DF GTC Y+ A TC
Sbjct: 45 CSTWGAGHFSTFDHHVYDFSGTCNYIFAATC 75
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 246 bits (627), Expect = 2e-64
Identities = 219/803 (27%), Positives = 314/803 (39%), Gaps = 92/803 (11%)
Query: 505 CEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCS 564
C + A G Q G VC G+ HY TFDG + G C Y C
Sbjct: 12 CLALSLAGGSELQTEGRTRN---HGHNVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCR 68
Query: 565 EDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEV----GFVLVDNQRSRL 620
+ F+V K + + V + + ++ LTR V + L
Sbjct: 69 --GSYKEFAVHLKRGPGQAEAPAGVESILLTIKDDTIYLTRHLAVLNGAVVSTPHYSPGL 126
Query: 621 PVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPA 680
+ S+ +VY GL + ++ + L L L +F++ CGLCG+YNG +
Sbjct: 127 LIEKSDAYTKVYSRA---------GLTLMWNREDALMLELDTKFRNHTCGLCGDYNGLQS 177
Query: 681 DDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPA-CTPGQAQHYEGDRLCGMLT 739
DG L +EF + K++ D +CED + PA C+ +A+ C L
Sbjct: 178 YSEFLSDGVLF-SPLEFGNMQKINQPDVVCEDPEEEVAPASCSEHRAE-------CERLL 229
Query: 740 KLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSP 799
+ FA C D + P+L C D C G +C ++ +++ C G G+WR+
Sbjct: 230 TAEA-FADCQDLVPLEPYLRACQQDRCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTA 288
Query: 800 ANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFV---ASGGACVP 856
CP +CP N Y G C +C+ S C ++GC C G V CVP
Sbjct: 289 TLCPKTCPGNLVYLESGSPCMDTCSHLEVSSLCEEHR-MDGCFCPEGTVYDDIGDSGCVP 347
Query: 857 ASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLG 916
S C C G PGQE+ D C+ +C CN + C+D CP
Sbjct: 348 VSQCHCRLHGHLYTPGQEITND--CE-QCVCNAG--RWVCKD-LPCP------------- 388
Query: 917 CYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQ 976
GTC G H +FDG+ + F G C Y+L N + L Q
Sbjct: 389 ------GTCALEGGSHITTFDGKTYTFHGDCYYVLAKG-DHNDSYALLGELAPCGSTDKQ 441
Query: 977 TVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFR-QGRDAVVRTD 1035
T T + + + V + + G VL++++ LP A VFR +V
Sbjct: 442 TCLKTVVLLADKKKNVVVFKSD--GSVLLNELQVNLPHVTA--SFSVFRPSSYHIMVSMA 497
Query: 1036 FGLTVTYDWNARVTAKVPSSYAE--ALCGLCGNFNGDPADDLALRGGGQAANALAFGNSW 1093
G+ + + V A + GLCGNFNG DD G A F N+W
Sbjct: 498 IGVRLQVQLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTW 557
Query: 1094 QEETRPGCGATEPGDCPKLDSLVAQQLQSKNE----CGILADPKGPFRECHSKLDPQGAV 1149
+ ++ C LD + ++S N C +L + PF CHS +DP
Sbjct: 558 KAQS--SC----HDKLDWLDDPCSLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYY 611
Query: 1150 RDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPL---SCPPHSHYEAC 1206
+ C YD C LC AL++YA AC A G + WR E +C SCP +
Sbjct: 612 KRCKYDTCNCQNNEDCLCAALSSYARACTAKGVMLWGWR-EHVCNKDVGSCPNSQVFLYN 670
Query: 1207 SYGCPLSCGDLPVPGGCGSECHE------GCVC-DEGFALSGESCLPLASCGCVHQGTYH 1259
C +C L S C E GC C D F C+PLA C C H+G Y
Sbjct: 671 LTTCQQTCRSL---SEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYL 727
Query: 1260 PPGQTFYPGPGCDSLCHCQEGGL 1282
G + C C++G L
Sbjct: 728 EAGDVVVRQ---EERCVCRDGRL 747
Score = 180 bits (456), Expect = 1e-44
Identities = 137/466 (29%), Positives = 206/466 (44%), Gaps = 57/466 (12%)
Query: 837 CVEGCVCLPGFVASG-GACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVT 895
CV GCVC G + G G CV C C + G ++ D CN T
Sbjct: 796 CVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVD--------CN------T 841
Query: 896 CRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGS- 954
C +C G Q C+ GTC G HY++FDG+ +DF G C+Y+ V
Sbjct: 842 C----TCKRGRWVCTQ---AVCH----GTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDY 890
Query: 955 CGQNAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPF 1014
CGQN++L +F ++ EN G+ V+ ++A+++ ++ + ++ V+ D ++ +
Sbjct: 891 CGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHR-VVIQRDEGHHVAY 949
Query: 1015 QAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADD 1074
+ G+ VV + G+ V +D V K+ SY +CGLCGNF+ +D
Sbjct: 950 TTRE-------VGQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNND 1002
Query: 1075 LALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKG 1134
R ++ L FGNSW+E +T P C ++ ++ +C IL
Sbjct: 1003 FTTRDHMVVSSELDFGNSWKEAPTCPDVSTNPEPCSLNPH---RRSWAEKQCSIL--KSS 1057
Query: 1135 PFRECHSKLDPQGAVRDCVYDRCLLP--GQSGPLCDALATYAAACQAAGATVHPWRSEEL 1192
F CHSK+DP+ CV+D C G C A+A+YA C GA V WR+ +L
Sbjct: 1058 VFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACVF-WRTPDL 1116
Query: 1193 CPLSC----PPHS---HYEACSYGCPLSCGDL-PVPGGCGSECHEGCV--CDEGFALSGE 1242
CP+ C PPH HYE C +C + + EGC C + + E
Sbjct: 1117 CPIFCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEE 1176
Query: 1243 ---SCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSC 1285
C+ CGC + T++PPG + C S C C V C
Sbjct: 1177 DLKKCVTADKCGCYVEDTHYPPGASVPTEETCKS-CVCTNSSQVVC 1221
Score = 160 bits (404), Expect = 1e-38
Identities = 118/404 (29%), Positives = 178/404 (44%), Gaps = 39/404 (9%)
Query: 516 CQVVGGKAGCV-AESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVE-LCSEDDTLPAFS 573
C G+ C A C G HY TFDG+ YD G CSY V+ C ++ +L +FS
Sbjct: 842 CTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFS 901
Query: 574 VEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQ 633
+ +N G+ V+ S ++ + G L D + R+ + EG Y
Sbjct: 902 IITENVPCGTTGVTC---------SKAIKIFMGRTELKLED--KHRVVIQRDEGHHVAYT 950
Query: 634 S---GPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGAL 690
+ G VVE G++V +D + + L ++ VCGLCGN++ +DF T D +
Sbjct: 951 TREVGQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMV 1010
Query: 691 APDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHD 750
++F +SWK C D N P C+ + ++ C +L F++CH
Sbjct: 1011 VSSELDFGNSWKEAP---TCPDVSTNPEP-CSLNPHRRSWAEKQCSILK--SSVFSICHS 1064
Query: 751 TLDPRPFLEQCVYDLCV--VGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSC-- 806
+DP+PF E CV+D C GG+ C +++YAQ C + G V WR+P CP+ C
Sbjct: 1065 KVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACV-FWRTPDLCPIFCDY 1123
Query: 807 -----PANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCV--C---LPGFVASGGACVP 856
YE CG +C + +EGC C P + CV
Sbjct: 1124 YNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVT 1183
Query: 857 ASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQ 900
A CGC + PG V +E C + C C ++ QV CR ++
Sbjct: 1184 ADKCGCYVEDTHYPPGASVPTEETC-KSCVCTNSS-QVVCRPEE 1225
Score = 141 bits (356), Expect = 4e-33
Identities = 122/393 (31%), Positives = 177/393 (45%), Gaps = 43/393 (10%)
Query: 533 CRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRGS--RRVSYVG 590
C +G H TTFDG+ Y G C Y + ++ D ++++ + GS ++
Sbjct: 391 CALEGGSHITTFDGKTYTFHGDCYYVL----AKGDHNDSYALLGELAPCGSTDKQTCLKT 446
Query: 591 LVTVRAYSHSVSLTRGEVGFVLVDNQRSRLP-VSLSEGRLRVYQSGPRAVVELVFG--LV 647
+V + +V + + + G VL++ + LP V+ S R S +V + G L
Sbjct: 447 VVLLADKKKNVVVFKSD-GSVLLNELQVNLPHVTASFSVFR--PSSYHIMVSMAIGVRLQ 503
Query: 648 VTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKL---- 703
V QL ++L Q QV GLCGN+NG DDF T G + FA++WK
Sbjct: 504 VQLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSC 563
Query: 704 -DDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCV 762
D D+L +D C N + A+H+ C +L K + PF CH +DP + ++C
Sbjct: 564 HDKLDWL-DDPCSLNIESAN--YAEHW-----CSLLKKTETPFGRCHSAVDPAEYYKRCK 615
Query: 763 YDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPL---SCPANSRYELCGPAC 819
YD C LC LS+YA+AC G+ + WR C SCP + + C
Sbjct: 616 YDTCNCQNNEDCLCAALSSYARACTAKGVMLWGWREHV-CNKDVGSCPNSQVFLYNLTTC 674
Query: 820 PTSCNG-AAAPSNC-SGRPCVEGCVCLP-GFVASGGACVPASSCGCTFQGLQLAPGQEVW 876
+C + A S+C G V+GC C F+ G CVP + C C +GL L G V
Sbjct: 675 QQTCRSLSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVV 734
Query: 877 ADELCQRRCTC-NGATHQVTCRD----KQSCPA 904
E RC C +G H CR QSC A
Sbjct: 735 RQE---ERCVCRDGRLH---CRQIRLIGQSCTA 761
Score = 138 bits (348), Expect = 3e-32
Identities = 126/429 (29%), Positives = 188/429 (43%), Gaps = 37/429 (8%)
Query: 510 CAAGQRCQVVGGKAGCVA--ESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDD 567
C+ G + V GC E C GDPHY TFDG Y G C+Y +VE S
Sbjct: 4456 CSNGLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEIS--P 4513
Query: 568 TLPAFSVEAKNEH-RGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSE 626
++ F V N H + +VS + VR + V + + + V Q +R V+L
Sbjct: 4514 SVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPY 4573
Query: 627 GR--LRVYQSGPRAVVEL-VFGLVVTYDWDCQLALSLP-ARFQDQVCGLCGNYNGDPADD 682
+ L VYQSG VV++ G++V+Y+ ++ LP RF + G CG +DD
Sbjct: 4574 KKYGLEVYQSGINYVVDIPELGVLVSYN-GLSFSVRLPYHRFGNNTKGQCGTCTNTTSDD 4632
Query: 683 FLTPDGALAPDAVEFASSWKLDDGD--YLCEDGCQNNCPACT-PGQAQ---HYE--GDRL 734
+ P G + + A W ++D + PA T PG + H + L
Sbjct: 4633 CILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPL 4692
Query: 735 CGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVG 794
C ++ D FA CH + P+ + + CV+D C + G L C L AYA C + I +
Sbjct: 4693 CQLIK--DSLFAQCHALVPPQHYYDACVFDSCFMPGSSLE-CASLQAYAALCAQQNICL- 4748
Query: 795 DWRSPAN--CPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFV-ASG 851
DWR+ + C + CP++ Y+ CGPA +C +++ N VEGC C G + +
Sbjct: 4749 DWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQN--NTVLVEGCFCPEGTMNYAP 4806
Query: 852 GACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQ 911
G V +CGC G P + E + C C + C+ K RCS Q
Sbjct: 4807 GFDVCVKTCGCV--GPDNVPREFGEHFEFDCKNCVCLEGGSGIICQPK-------RCS-Q 4856
Query: 912 NGLLGCYPD 920
+ C D
Sbjct: 4857 KPVTHCVED 4865
Score = 132 bits (333), Expect = 2e-30
Identities = 109/426 (25%), Positives = 172/426 (40%), Gaps = 52/426 (12%)
Query: 925 CQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAV 984
C G+ HY +FDG F F G C Y C + F V ++ ++ + ++
Sbjct: 37 CSTWGNFHYKTFDGDVFRFPGLCDYNFASDC--RGSYKEFAVHLKRGPGQAEAPAGVESI 94
Query: 985 RVEARGVKVAVRREYPGQVLVDDVLQ---YLP---FQAADGQVQVFRQGRDAVVRTDFGL 1038
+ + + + R VL V+ Y P + +D +V+ + GL
Sbjct: 95 LLTIKDDTIYLTRHLA--VLNGAVVSTPHYSPGLLIEKSDAYTKVYSRA---------GL 143
Query: 1039 TVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETR 1098
T+ ++ + ++ + + CGLCG++NG + L G + L FGN Q+ +
Sbjct: 144 TLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFL-SDGVLFSPLEFGNM-QKINQ 201
Query: 1099 PGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCL 1158
P +P + + A + + EC L + F +C + + +R C DRC
Sbjct: 202 PDVVCEDPEE----EVAPASCSEHRAECERLLTAEA-FADCQDLVPLEPYLRACQQDRCR 256
Query: 1159 LPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLP 1218
PG +C +A ++ C AG WR+ LCP +CP + Y C +C L
Sbjct: 257 CPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATLCPKTCPGNLVYLESGSPCMDTCSHLE 316
Query: 1219 VPGGCGSECHEGCVCDEGFA---LSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLC 1275
V C +GC C EG + C+P++ C C G + PGQ C+ C
Sbjct: 317 VSSLCEEHRMDGCFCPEGTVYDDIGDSGCVPVSQCHCRLHGHLYTPGQEI--TNDCEQ-C 373
Query: 1276 HCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTC 1335
C G V C+ C TC G H TTFDG+ + F G C
Sbjct: 374 VCNAGRWV-CKDLPC-------------------PGTCALEGGSHITTFDGKTYTFHGDC 413
Query: 1336 VYVLAQ 1341
YVLA+
Sbjct: 414 YYVLAK 419
Score = 119 bits (297), Expect = 3e-26
Identities = 121/456 (26%), Positives = 178/456 (39%), Gaps = 59/456 (12%)
Query: 886 TCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMG 945
TC+ V D C C CY C G GDPHYV+FDG + + G
Sbjct: 4455 TCSNGLQPVRVEDPDGCCWHWECD-------CY------CTGWGDPHYVTFDGLYYSYQG 4501
Query: 946 TCTYLLVGSCGQNAALPAFRVLVENEH---RGSQTVSYTRAVRVEARGVKVAVRREYPGQ 1002
CTY+LV + ++ F V ++N H + T VR E + V + P Q
Sbjct: 4502 NCTYVLVEEI--SPSVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQ 4559
Query: 1003 VLVDDVLQYLPFQAADGQVQVFRQGRDAVVR-TDFGLTVTYDWNARVTAKVP-SSYAEAL 1060
V V Q + ++V++ G + VV + G+ V+Y+ + ++P +
Sbjct: 4560 VQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVLVSYN-GLSFSVRLPYHRFGNNT 4618
Query: 1061 CGLCGNFNGDPADDLALRGGGQAANALAFGNSW--QEETRPGC----------GATEPG- 1107
G CG +DD L G +N A + W + ++P C T PG
Sbjct: 4619 KGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGG 4678
Query: 1108 --DCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGP 1165
P D + C ++ D F +CH+ + PQ CV+D C +PG S
Sbjct: 4679 GKTTPHKDCTPSPL------CQLIKD--SLFAQCHALVPPQHYYDACVFDSCFMPGSSLE 4730
Query: 1166 LCDALATYAAACQAAGATVHPWRSEE--LCPLSCPPHSHYEACSYGCPLSCGDLPVPGGC 1223
C +L YAA C + WR+ C + CP H Y+AC +C
Sbjct: 4731 -CASLQAYAALCAQQNICL-DWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQN- 4787
Query: 1224 GSECHEGCVCDEG---FALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEG 1280
+ EGC C EG +A + C + +CGCV G + P + C C EG
Sbjct: 4788 NTVLVEGCFCPEGTMNYAPGFDVC--VKTCGCV--GPDNVPREFGEHFEFDCKNCVCLEG 4843
Query: 1281 GL-VSCESSSCG--PHEACQPSGGSLGCVAVGSSTC 1313
G + C+ C P C G L + TC
Sbjct: 4844 GSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTC 4879
Score = 82.0 bits (201), Expect = 4e-15
Identities = 76/271 (28%), Positives = 102/271 (37%), Gaps = 35/271 (12%)
Query: 1140 HSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCP- 1198
H+ LD +G C G D + C +H R L SC
Sbjct: 703 HTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEERCVCRDGRLH-CRQIRLIGQSCTA 761
Query: 1199 PHSHYE-------ACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGES-CLPLASC 1250
P H + A S LSC L G +EC GCVC +G G C+ C
Sbjct: 762 PKIHMDCSNLTALATSKPRALSCQTLAA-GYYHTECVSGCVCPDGLMDDGRGGCVVEKEC 820
Query: 1251 GCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGS 1310
CVH + G C++ C C+ G V + AV
Sbjct: 821 PCVHNNDLYSSGAKIKVD--CNT-CTCKRGRWVCTQ--------------------AVCH 857
Query: 1311 STCQASGDPHYTTFDGRRFDFMGTCVYVLAQT-CGTRPGLHRFAVLQENVAWGNGRVSVT 1369
TC G HY TFDG+ +DF G C YV Q CG L F+++ ENV G V+ +
Sbjct: 858 GTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVTCS 917
Query: 1370 RVITVQVANFTLRLEQRQWKVTVRADGEQGA 1400
+ I + + L+LE + V R +G A
Sbjct: 918 KAIKIFMGRTELKLEDKHRVVIQRDEGHHVA 948
Score = 46.2 bits (108), Expect = 2e-04
Identities = 24/64 (37%), Positives = 32/64 (50%), Gaps = 3/64 (4%)
Query: 1313 CQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWG-NGRVSVTRV 1371
C GDPHY TFDG + + G C YVL + P + F V +N N +VS R
Sbjct: 4481 CTGWGDPHYVTFDGLYYSYQGNCTYVLVEEIS--PSVDNFGVYIDNYHCDPNDKVSCPRT 4538
Query: 1372 ITVQ 1375
+ V+
Sbjct: 4539 LIVR 4542
Score = 37.0 bits (84), Expect = 0.14
Identities = 20/46 (43%), Positives = 22/46 (47%), Gaps = 2/46 (4%)
Query: 1309 GSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAV 1354
G + C G+ HY TFDG F F G C Y A C R FAV
Sbjct: 33 GHNVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDC--RGSYKEFAV 76
>gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo
sapiens]
Length = 2134
Score = 221 bits (563), Expect = 4e-57
Identities = 224/883 (25%), Positives = 339/883 (38%), Gaps = 146/883 (16%)
Query: 513 GQRCQVVGGKAGCV-AESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPA 571
G +C K C A C+ +G TTFDG +Y+ G C + V +ED ++
Sbjct: 837 GSQCTCQDAKWSCTEALCPGRCKVEGSS-LTTFDGVKYNFPGNCHFLAVH--NEDWSISV 893
Query: 572 FSVEAKNEHRGSRRVSYVGL----VTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEG 627
+ G+ S L V V Y + T V N + R
Sbjct: 894 ELRPCPSGQTGTCLNSVTLLLNSSVPVDKYVFNSDGT--------VTNDKIRNQGYYYSD 945
Query: 628 RLRVYQSGPRAV-VELVFG--LVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFL 684
+++++ + + VE F L + QL +S+P GLCG+YN DDF+
Sbjct: 946 KIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFM 1005
Query: 685 TPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGP 744
+ L + FA+SW++ C G N +C + + + +R CG+L GP
Sbjct: 1006 SSQNILEKTSQAFANSWEMMS----CPKG---NPSSCISIEKEKF-AERHCGILLDSSGP 1057
Query: 745 FAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPL 804
A CH ++P+P+ E+C C + LC L Y +AC E + WR+ C
Sbjct: 1058 LASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGL-CEH 1116
Query: 805 SCPANSRYELCGPACPTSCNGAAAPSNCSGRPC------VEGCVCLPGFVASG-GACVPA 857
SCP+ ++ AC +SC + R C V+GC C + G CV
Sbjct: 1117 SCPSGLVFKYNVKACNSSCRSLSERD----RSCDVEDVPVDGCTCPDAMYQNNEGNCVLK 1172
Query: 858 SSCGCTFQGLQLAPGQEVWADE----------LCQRRC-----TCNGATHQVTCRDKQS- 901
S C C + PG+ + D+ LCQ C+G V C D ++
Sbjct: 1173 SQCDCYINDEVMQPGKLIHIDDNKCVCRDGILLCQIPIDLTLQNCSGGAEYVDCSDPKAQ 1232
Query: 902 --------------------------CPAG------------------------------ 905
CP G
Sbjct: 1233 RRTNRTCSTRNIPVFDENLPCKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYDEGSVT 1292
Query: 906 ----ERCSVQNGLLGCYPDRFGT-CQGSGDPHYVSFDGRRFDFMGTCTY-LLVGSCGQNA 959
C+ G C + T C G+ H +FDG+ + F G C Y L CG
Sbjct: 1293 SVGCNECTCIKGSWSCTQNECQTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHEN 1352
Query: 960 ALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADG 1019
FR+L E+ ++ +R + V + + ++ G+V + +
Sbjct: 1353 G--TFRILTESVPCCEDGLTCSRKIIVAFQDQNIVLQ---DGKVTAVKSTESKKCELNAN 1407
Query: 1020 QVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRG 1079
+ G +++ G+ V +D N R++ + ++ +CGLCGN NGD DD R
Sbjct: 1408 AYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRY 1467
Query: 1080 GGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFREC 1139
A+ AL FGNSW +T C T P DS + + +C IL D FR+C
Sbjct: 1468 SSVASGALEFGNSW--KTSQECSDTVAQTFP-CDSNPYCKAWAVRKCEILRD--STFRDC 1522
Query: 1140 HSKLDPQGAVRDCVYDRCL--LPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSC 1197
H+K+DP C+ + C + G+ C A+A YA AC A G V WR LCP+ C
Sbjct: 1523 HNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCV-SWRKPNLCPVYC 1581
Query: 1198 PPHS-------HYEACSYGCPLSCGDLPVPGGCGSECHEGCV--CDEGFALSGES---CL 1245
++ HYE C +C D V G S EGC C + E+ C+
Sbjct: 1582 DYYNAPGECRWHYEPCGTVTAKTCKDQLV-GQKFSSLLEGCYAKCPDSAPYLDENTMKCV 1640
Query: 1246 PLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESS 1288
L+ C C + P G C C+C G L E++
Sbjct: 1641 SLSECSCFYNDVI-PAGGVI--EDNCGRTCYCIAGQLECSETA 1680
Score = 139 bits (349), Expect = 3e-32
Identities = 107/399 (26%), Positives = 167/399 (41%), Gaps = 34/399 (8%)
Query: 506 EGMQCAAG-QRCQVVGGKAGCVA-ESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVE-L 562
EG + G C + G C E +C G+ H TFDG+ Y G C Y+ +E
Sbjct: 1288 EGSVTSVGCNECTCIKGSWSCTQNECQTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDY 1347
Query: 563 CSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPV 622
C ++ F + ++ ++ + V ++ L G+V V +
Sbjct: 1348 CGHENG--TFRILTESVPCCEDGLTCSRKIIVAFQDQNIVLQDGKVTAVKSTESKK---C 1402
Query: 623 SLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADD 682
L+ ++ G +++ G++V +D + +L++ L + +VCGLCGN NGD DD
Sbjct: 1403 ELNANAYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDD 1462
Query: 683 FLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLD 742
F T ++A A+EF +SWK C D P C R C +L D
Sbjct: 1463 FTTRYSSVASGALEFGNSWKTSQE---CSDTVAQTFP-CDSNPYCKAWAVRKCEILR--D 1516
Query: 743 GPFAVCHDTLDPRPFLEQCVYDLCV--VGGERLSLCRGLSAYAQACLELGISVGDWRSPA 800
F CH+ +DP + + C+ + C + G+ L C ++ YA+AC +G+ V WR P
Sbjct: 1517 STFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCV-SWRKPN 1575
Query: 801 NCPLSC-----PANSR--YELCGPACPTSCNGAAAPSNCSGRPCVEGCVC-----LPGFV 848
CP+ C P R YE CG +C S +EGC P
Sbjct: 1576 LCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQKFSS--LLEGCYAKCPDSAPYLD 1633
Query: 849 ASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTC 887
+ CV S C C + + A G ++ C R C C
Sbjct: 1634 ENTMKCVSLSECSCFYNDVIPAGGV---IEDNCGRTCYC 1669
Score = 131 bits (330), Expect = 4e-30
Identities = 136/590 (23%), Positives = 224/590 (37%), Gaps = 80/590 (13%)
Query: 709 LCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVV 768
+CEDG Q+ C ++E CG + L + + C+ + C
Sbjct: 681 VCEDGIQH----CNKIIGTYFEK---CGKVAALSNDYKMI------------CIDEYCQT 721
Query: 769 GGERLSLCRGLSAYAQACLELGISVGD-WRSPANCPLS---CPANSRYELCGPACPTSCN 824
++ S C S ++ C G + WRS ++ CP Y+ CGP+ P +C+
Sbjct: 722 R-DKTSTCDTYSELSRLCASDGPGTFESWRSDSDVVCETQRCPEQHIYKECGPSNPATCS 780
Query: 825 GAAAPSNCSGRPCVEGCVCLPGF----VASGGACVPASSCGCTFQGLQLAPGQEVWADEL 880
A + CV GC C G+ + G CV + C C G PG+ +
Sbjct: 781 NVAPFQDSE---CVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGEV--REGP 835
Query: 881 CQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRR 940
C +CTC A T + CP RC V+ L +FDG +
Sbjct: 836 CGSQCTCQDAKWSCT---EALCPG--RCKVEGSSL------------------TTFDGVK 872
Query: 941 FDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYP 1000
++F G C +L V + ++ ++ + G+ S T + K +
Sbjct: 873 YNFPGNCHFLAVHN--EDWSISVELRPCPSGQTGTCLNSVTLLLNSSVPVDKYVFNSD-- 928
Query: 1001 GQVLVDDVLQYLPFQAADGQVQVFRQGRDAV-VRTDF--GLTVTYDWNARVTAKVPSSYA 1057
+ +D ++ + +D ++Q+F + V T F L + ++ +P +
Sbjct: 929 -GTVTNDKIRNQGYYYSD-KIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQF 986
Query: 1058 EALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVA 1117
GLCG++N DD + AF NSW+ C P C ++
Sbjct: 987 TDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWE---MMSCPKGNPSSCISIE---- 1039
Query: 1118 QQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAAC 1177
++ ++ CGIL D GP CH ++P+ +C C LC L Y AC
Sbjct: 1040 KEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKAC 1099
Query: 1178 QAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPV-PGGCGSE--CHEGCVCD 1234
+ WR+ LC SCP ++ C SC L C E +GC C
Sbjct: 1100 AEKETYIVGWRT-GLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCP 1158
Query: 1235 EGFALSGE-SCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLV 1283
+ + E +C+ + C C PG+ + D+ C C++G L+
Sbjct: 1159 DAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHID---DNKCVCRDGILL 1205
Score = 73.6 bits (179), Expect = 1e-12
Identities = 59/195 (30%), Positives = 83/195 (42%), Gaps = 34/195 (17%)
Query: 1152 CVYDRCLLPGQSGPLCDALATYAAACQAAG-ATVHPWRSEE--LCPLS-CPPHSHYEACS 1207
C+ + C ++ CD + + C + G T WRS+ +C CP Y+ C
Sbjct: 714 CIDEYCQTRDKTST-CDTYSELSRLCASDGPGTFESWRSDSDVVCETQRCPEQHIYKECG 772
Query: 1208 YGCPLSCGDLPVPGGCGSECHEGCVCDEGFALS--GE--SCLPLASCGCVHQGTYHPPGQ 1263
P +C + V SEC GC C EG+ L GE C+ A C C GT + PG+
Sbjct: 773 PSNPATCSN--VAPFQDSECVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGE 830
Query: 1264 TFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTT 1323
GP C S C CQ+ SC + C C+ G SL TT
Sbjct: 831 V-REGP-CGSQCTCQDAKW-SCTEALCPGR--CKVEGSSL------------------TT 867
Query: 1324 FDGRRFDFMGTCVYV 1338
FDG +++F G C ++
Sbjct: 868 FDGVKYNFPGNCHFL 882
Score = 50.1 bits (118), Expect = 2e-05
Identities = 41/150 (27%), Positives = 57/150 (38%), Gaps = 27/150 (18%)
Query: 1227 CHEGCVCDEGFALSGES-CLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSC 1285
C GC C EG + + C+ C C G + G GC+ C C +G SC
Sbjct: 1253 CKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYDEGSV--TSVGCNE-CTCIKGSW-SC 1308
Query: 1286 ESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVY-VLAQTCG 1344
+ C + C G+ H TFDG+ + F G C Y L CG
Sbjct: 1309 TQNEC-------------------QTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCG 1349
Query: 1345 TRPGLHRFAVLQENVAWGNGRVSVTRVITV 1374
G F +L E+V ++ +R I V
Sbjct: 1350 HENG--TFRILTESVPCCEDGLTCSRKIIV 1377
>gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo
sapiens]
Length = 2134
Score = 221 bits (563), Expect = 4e-57
Identities = 224/883 (25%), Positives = 339/883 (38%), Gaps = 146/883 (16%)
Query: 513 GQRCQVVGGKAGCV-AESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPA 571
G +C K C A C+ +G TTFDG +Y+ G C + V +ED ++
Sbjct: 837 GSQCTCQDAKWSCTEALCPGRCKVEGSS-LTTFDGVKYNFPGNCHFLAVH--NEDWSISV 893
Query: 572 FSVEAKNEHRGSRRVSYVGL----VTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEG 627
+ G+ S L V V Y + T V N + R
Sbjct: 894 ELRPCPSGQTGTCLNSVTLLLNSSVPVDKYVFNSDGT--------VTNDKIRNQGYYYSD 945
Query: 628 RLRVYQSGPRAV-VELVFG--LVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFL 684
+++++ + + VE F L + QL +S+P GLCG+YN DDF+
Sbjct: 946 KIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFM 1005
Query: 685 TPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGP 744
+ L + FA+SW++ C G N +C + + + +R CG+L GP
Sbjct: 1006 SSQNILEKTSQAFANSWEMMS----CPKG---NPSSCISIEKEKF-AERHCGILLDSSGP 1057
Query: 745 FAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPL 804
A CH ++P+P+ E+C C + LC L Y +AC E + WR+ C
Sbjct: 1058 LASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGL-CEH 1116
Query: 805 SCPANSRYELCGPACPTSCNGAAAPSNCSGRPC------VEGCVCLPGFVASG-GACVPA 857
SCP+ ++ AC +SC + R C V+GC C + G CV
Sbjct: 1117 SCPSGLVFKYNVKACNSSCRSLSERD----RSCDVEDVPVDGCTCPDAMYQNNEGNCVLK 1172
Query: 858 SSCGCTFQGLQLAPGQEVWADE----------LCQRRC-----TCNGATHQVTCRDKQS- 901
S C C + PG+ + D+ LCQ C+G V C D ++
Sbjct: 1173 SQCDCYINDEVMQPGKLIHIDDNKCVCRDGILLCQIPIDLTLQNCSGGAEYVDCSDPKAQ 1232
Query: 902 --------------------------CPAG------------------------------ 905
CP G
Sbjct: 1233 RRTNRTCSTRNIPVFDENLPCKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYDEGSVT 1292
Query: 906 ----ERCSVQNGLLGCYPDRFGT-CQGSGDPHYVSFDGRRFDFMGTCTY-LLVGSCGQNA 959
C+ G C + T C G+ H +FDG+ + F G C Y L CG
Sbjct: 1293 SVGCNECTCIKGSWSCTQNECQTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHEN 1352
Query: 960 ALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADG 1019
FR+L E+ ++ +R + V + + ++ G+V + +
Sbjct: 1353 G--TFRILTESVPCCEDGLTCSRKIIVAFQDQNIVLQ---DGKVTAVKSTESKKCELNAN 1407
Query: 1020 QVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRG 1079
+ G +++ G+ V +D N R++ + ++ +CGLCGN NGD DD R
Sbjct: 1408 AYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRY 1467
Query: 1080 GGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFREC 1139
A+ AL FGNSW +T C T P DS + + +C IL D FR+C
Sbjct: 1468 SSVASGALEFGNSW--KTSQECSDTVAQTFP-CDSNPYCKAWAVRKCEILRD--STFRDC 1522
Query: 1140 HSKLDPQGAVRDCVYDRCL--LPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSC 1197
H+K+DP C+ + C + G+ C A+A YA AC A G V WR LCP+ C
Sbjct: 1523 HNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCV-SWRKPNLCPVYC 1581
Query: 1198 PPHS-------HYEACSYGCPLSCGDLPVPGGCGSECHEGCV--CDEGFALSGES---CL 1245
++ HYE C +C D V G S EGC C + E+ C+
Sbjct: 1582 DYYNAPGECRWHYEPCGTVTAKTCKDQLV-GQKFSSLLEGCYAKCPDSAPYLDENTMKCV 1640
Query: 1246 PLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESS 1288
L+ C C + P G C C+C G L E++
Sbjct: 1641 SLSECSCFYNDVI-PAGGVI--EDNCGRTCYCIAGQLECSETA 1680
Score = 139 bits (349), Expect = 3e-32
Identities = 107/399 (26%), Positives = 167/399 (41%), Gaps = 34/399 (8%)
Query: 506 EGMQCAAG-QRCQVVGGKAGCVA-ESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVE-L 562
EG + G C + G C E +C G+ H TFDG+ Y G C Y+ +E
Sbjct: 1288 EGSVTSVGCNECTCIKGSWSCTQNECQTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDY 1347
Query: 563 CSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPV 622
C ++ F + ++ ++ + V ++ L G+V V +
Sbjct: 1348 CGHENG--TFRILTESVPCCEDGLTCSRKIIVAFQDQNIVLQDGKVTAVKSTESKK---C 1402
Query: 623 SLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADD 682
L+ ++ G +++ G++V +D + +L++ L + +VCGLCGN NGD DD
Sbjct: 1403 ELNANAYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDD 1462
Query: 683 FLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLD 742
F T ++A A+EF +SWK C D P C R C +L D
Sbjct: 1463 FTTRYSSVASGALEFGNSWKTSQE---CSDTVAQTFP-CDSNPYCKAWAVRKCEILR--D 1516
Query: 743 GPFAVCHDTLDPRPFLEQCVYDLCV--VGGERLSLCRGLSAYAQACLELGISVGDWRSPA 800
F CH+ +DP + + C+ + C + G+ L C ++ YA+AC +G+ V WR P
Sbjct: 1517 STFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCV-SWRKPN 1575
Query: 801 NCPLSC-----PANSR--YELCGPACPTSCNGAAAPSNCSGRPCVEGCVC-----LPGFV 848
CP+ C P R YE CG +C S +EGC P
Sbjct: 1576 LCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQKFSS--LLEGCYAKCPDSAPYLD 1633
Query: 849 ASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTC 887
+ CV S C C + + A G ++ C R C C
Sbjct: 1634 ENTMKCVSLSECSCFYNDVIPAGGV---IEDNCGRTCYC 1669
Score = 131 bits (330), Expect = 4e-30
Identities = 136/590 (23%), Positives = 224/590 (37%), Gaps = 80/590 (13%)
Query: 709 LCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVV 768
+CEDG Q+ C ++E CG + L + + C+ + C
Sbjct: 681 VCEDGIQH----CNKIIGTYFEK---CGKVAALSNDYKMI------------CIDEYCQT 721
Query: 769 GGERLSLCRGLSAYAQACLELGISVGD-WRSPANCPLS---CPANSRYELCGPACPTSCN 824
++ S C S ++ C G + WRS ++ CP Y+ CGP+ P +C+
Sbjct: 722 R-DKTSTCDTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECGPSNPATCS 780
Query: 825 GAAAPSNCSGRPCVEGCVCLPGF----VASGGACVPASSCGCTFQGLQLAPGQEVWADEL 880
A + CV GC C G+ + G CV + C C G PG+ +
Sbjct: 781 NVAPFQDSE---CVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGEV--REGP 835
Query: 881 CQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRR 940
C +CTC A T + CP RC V+ L +FDG +
Sbjct: 836 CGSQCTCQDAKWSCT---EALCPG--RCKVEGSSL------------------TTFDGVK 872
Query: 941 FDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYP 1000
++F G C +L V + ++ ++ + G+ S T + K +
Sbjct: 873 YNFPGNCHFLAVHN--EDWSISVELRPCPSGQTGTCLNSVTLLLNSSVPVDKYVFNSD-- 928
Query: 1001 GQVLVDDVLQYLPFQAADGQVQVFRQGRDAV-VRTDF--GLTVTYDWNARVTAKVPSSYA 1057
+ +D ++ + +D ++Q+F + V T F L + ++ +P +
Sbjct: 929 -GTVTNDKIRNQGYYYSD-KIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQF 986
Query: 1058 EALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVA 1117
GLCG++N DD + AF NSW+ C P C ++
Sbjct: 987 TDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWE---MMSCPKGNPSSCISIE---- 1039
Query: 1118 QQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAAC 1177
++ ++ CGIL D GP CH ++P+ +C C LC L Y AC
Sbjct: 1040 KEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKAC 1099
Query: 1178 QAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPV-PGGCGSE--CHEGCVCD 1234
+ WR+ LC SCP ++ C SC L C E +GC C
Sbjct: 1100 AEKETYIVGWRT-GLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCP 1158
Query: 1235 EGFALSGE-SCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLV 1283
+ + E +C+ + C C PG+ + D+ C C++G L+
Sbjct: 1159 DAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHID---DNKCVCRDGILL 1205
Score = 73.2 bits (178), Expect = 2e-12
Identities = 59/195 (30%), Positives = 83/195 (42%), Gaps = 34/195 (17%)
Query: 1152 CVYDRCLLPGQSGPLCDALATYAAACQAAG-ATVHPWRSEE--LCPLS-CPPHSHYEACS 1207
C+ + C ++ CD + + C + G T WRS+ +C CP Y+ C
Sbjct: 714 CIDEYCQTRDKTST-CDTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECG 772
Query: 1208 YGCPLSCGDLPVPGGCGSECHEGCVCDEGFALS--GE--SCLPLASCGCVHQGTYHPPGQ 1263
P +C + V SEC GC C EG+ L GE C+ A C C GT + PG+
Sbjct: 773 PSNPATCSN--VAPFQDSECVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGE 830
Query: 1264 TFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTT 1323
GP C S C CQ+ SC + C C+ G SL TT
Sbjct: 831 V-REGP-CGSQCTCQDAKW-SCTEALCPGR--CKVEGSSL------------------TT 867
Query: 1324 FDGRRFDFMGTCVYV 1338
FDG +++F G C ++
Sbjct: 868 FDGVKYNFPGNCHFL 882
Score = 50.1 bits (118), Expect = 2e-05
Identities = 41/150 (27%), Positives = 57/150 (38%), Gaps = 27/150 (18%)
Query: 1227 CHEGCVCDEGFALSGES-CLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSC 1285
C GC C EG + + C+ C C G + G GC+ C C +G SC
Sbjct: 1253 CKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYDEGSV--TSVGCNE-CTCIKGSW-SC 1308
Query: 1286 ESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVY-VLAQTCG 1344
+ C + C G+ H TFDG+ + F G C Y L CG
Sbjct: 1309 TQNEC-------------------QTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCG 1349
Query: 1345 TRPGLHRFAVLQENVAWGNGRVSVTRVITV 1374
G F +L E+V ++ +R I V
Sbjct: 1350 HENG--TFRILTESVPCCEDGLTCSRKIIV 1377
>gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens]
Length = 1503
Score = 199 bits (507), Expect = 1e-50
Identities = 132/388 (34%), Positives = 177/388 (45%), Gaps = 43/388 (11%)
Query: 504 SCEGMQCAAG------QRCQVVG---GKAGCVAEST---------AVCRAQGDPHYTTFD 545
+C C AG QRC + KA ++ + A C A GDPHY TFD
Sbjct: 1103 TCTSCSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPASCMAFGDPHYRTFD 1162
Query: 546 GRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTR 605
GR G+CSY + + C D FSV N+ RG V++ V V +V L +
Sbjct: 1163 GRLLHFQGSCSYVLAKDCHSGD----FSVHVTNDDRGRSGVAWTQEVAVLLGDMAVRLLQ 1218
Query: 606 GEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQ 665
G V VD LP L E L V G ++ GL V +D Q+ +S+P +Q
Sbjct: 1219 D--GAVTVDGHPVALPF-LQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSYQ 1275
Query: 666 DQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDY---LCEDGCQNNCPACT 722
+ CGLCGN+NG DD P+G L P F +SW++ +G + C G + + P
Sbjct: 1276 GRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVD-PCRA 1334
Query: 723 PGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVG---GERLSLCRGL 779
G E + CG+L PF+ CH + P PF CVYDLC G LC L
Sbjct: 1335 AGYRARREANARCGVLK--SSPFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDAL 1392
Query: 780 SAYAQACLELGISVGDWRSPANCPLSCPANSR--YELCGPACPTSCNGAAAP-----SNC 832
AYA C + G++ WR P C + CP ++ CGP CP +C P ++C
Sbjct: 1393 EAYASHCRQAGVT-PTWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLGELAAHC 1451
Query: 833 SGRPCVEGCVCLPGFVASGGACVPASSC 860
RPCV GC C G V C+P +C
Sbjct: 1452 V-RPCVPGCQCPAGLVEHEAHCIPPEAC 1478
Score = 192 bits (488), Expect = 2e-48
Identities = 144/423 (34%), Positives = 195/423 (46%), Gaps = 41/423 (9%)
Query: 852 GACVP---ASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQ----SCPA 904
G+C P A + C QG ++A G+ W + C C+C T V C+ ++ SC
Sbjct: 1073 GSCCPVCRAPTQSCVHQGREVASGER-WTVDTCTS-CSCMAGT--VRCQSQRCSPLSCGP 1128
Query: 905 GERCSVQNGLLGCYP---DRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL 961
+ ++ G C P R +C GDPHY +FDGR F G+C+Y+L C
Sbjct: 1129 DKAPALSPG--SCCPRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKDCHSGD-- 1184
Query: 962 PAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQV 1021
F V V N+ RG V++T+ V V + AVR G V VD LPF + +
Sbjct: 1185 --FSVHVTNDDRGRSGVAWTQEVAVLLGDM--AVRLLQDGAVTVDGHPVALPF-LQEPLL 1239
Query: 1022 QVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGG 1081
V +G ++ GL V +D ++V VP SY CGLCGNFNG DDL G
Sbjct: 1240 YVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGL 1299
Query: 1082 QAANALAFGNSWQ--EETRPG--CGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFR 1137
+ AFGNSWQ E PG C A D + A++ ++ CG+L PF
Sbjct: 1300 LLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPCRAAGYRARR-EANARCGVL--KSSPFS 1356
Query: 1138 ECHSKLDPQGAVRDCVYDRCLL-PGQSGP--LCDALATYAAACQAAGATVHPWRSEELCP 1194
CH+ + P+ CVYD C PG S LCDAL YA+ C+ AG T WR LC
Sbjct: 1357 RCHAVVPPEPFFAACVYDLCACGPGSSADACLCDALEAYASHCRQAGVT-PTWRGPTLCV 1415
Query: 1195 LSCPPHSH--YEACSYGCPLSCGDLPVPGG-----CGSECHEGCVCDEGFALSGESCLPL 1247
+ CP ++ C CP +C + +P G C C GC C G C+P
Sbjct: 1416 VGCPLERGFVFDECGPPCPRTCFNQHIPLGELAAHCVRPCVPGCQCPAGLVEHEAHCIPP 1475
Query: 1248 ASC 1250
+C
Sbjct: 1476 EAC 1478
Score = 73.9 bits (180), Expect = 1e-12
Identities = 67/191 (35%), Positives = 85/191 (44%), Gaps = 35/191 (18%)
Query: 1203 YEAC-SYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPP 1261
++AC CPLS P PG C C P SC VHQG
Sbjct: 1055 HQACPELSCPLSERHTP-PGSCCPVCRA----------------PTQSC--VHQGREVAS 1095
Query: 1262 GQTFYPGPGCDSLCHCQEGGLVSCESS-----SCGPHEACQPSGGSL--GCVAVGSSTCQ 1314
G+ + C S C C G V C+S SCGP +A S GS C+ +S C
Sbjct: 1096 GERWTVDT-CTS-CSCM-AGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPAS-CM 1151
Query: 1315 ASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITV 1374
A GDPHY TFDGR F G+C YVLA+ C + F+V N G V+ T+ + V
Sbjct: 1152 AFGDPHYRTFDGRLLHFQGSCSYVLAKDCHSGD----FSVHVTNDDRGRSGVAWTQEVAV 1207
Query: 1375 QVANFTLRLEQ 1385
+ + +RL Q
Sbjct: 1208 LLGDMAVRLLQ 1218
Score = 51.2 bits (121), Expect = 7e-06
Identities = 68/227 (29%), Positives = 81/227 (35%), Gaps = 40/227 (17%)
Query: 1132 PKGPFRECHSKL-DPQGAVRDCVYDRC----LLPGQSGPLCDALATYAAACQAAGATVHP 1186
P P R C + Q R CV C LLPG+ P C A A C GA H
Sbjct: 558 PSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECCPQCPA----PAGCPRPGAA-HA 612
Query: 1187 WRSEELCPLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLP 1246
E P P C G +SC LP P + +G C
Sbjct: 613 RHQEYFSPPGDPCRRCL--CLDGS-VSCQRLPCPPAPCAHPRQGPCCP------------ 657
Query: 1247 LASC-GCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSL-- 1303
SC GC++QG G+ F LC C EG VSCE +C P P+ G
Sbjct: 658 --SCDGCLYQGKEFASGERFPSPTAACHLCLCWEGS-VSCEPKACAPALCPFPARGDCCP 714
Query: 1304 ---GCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRP 1347
GC +G S P D R + TC+ TCG RP
Sbjct: 715 DCDGCEYLGESYLSNQEFP-----DPREPCNLCTCLGGFV-TCGRRP 755
Score = 47.4 bits (111), Expect = 1e-04
Identities = 49/191 (25%), Positives = 66/191 (34%), Gaps = 56/191 (29%)
Query: 1159 LPGQSGPLCDALATYAAACQAAGATVHPWRSEE--------LCPLSCPPHSHYEACS-YG 1209
+PGQ P+CD C+ G H ++S+E LC + C + +C
Sbjct: 299 IPGQCCPVCDG-------CEYQG---HQYQSQETFRLQERGLC-VRCSCQAGEVSCEEQE 347
Query: 1210 CPLSCGDLPVPG-----GC---GSECHEG------------CVCDEGFALSGESCLPLAS 1249
CP++ LP G C G E EG CVC +G G P A
Sbjct: 348 CPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAP 407
Query: 1250 C---------------GCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHE 1294
C C + + GQ F CHCQ+ G V+C C P
Sbjct: 408 CQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADSPCHACHCQD-GTVTCSLVDCPPTT 466
Query: 1295 ACQPSGGSLGC 1305
+P G C
Sbjct: 467 CARPQSGPGQC 477
Score = 42.7 bits (99), Expect = 0.003
Identities = 60/218 (27%), Positives = 75/218 (34%), Gaps = 45/218 (20%)
Query: 1155 DRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELC------PLSCPPHSHYEACSY 1208
D CL G+ + + AAC W C P CP + + C
Sbjct: 660 DGCLYQGKEFASGERFPSPTAACHLCLC----WEGSVSCEPKACAPALCPFPARGDCCPD 715
Query: 1209 --GCP------LSCGDLPVP----------GG---CGSECHEGCVCDEGFALSGESCLPL 1247
GC LS + P P GG CG E C SG C
Sbjct: 716 CDGCEYLGESYLSNQEFPDPREPCNLCTCLGGFVTCGRRPCEPPGCSHPLIPSGHCC--- 772
Query: 1248 ASC-GCVHQGTYHPPGQTFYP--GPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLG 1304
+C GC + G G+T P C SLC CQEG + C+ C P PS G
Sbjct: 773 PTCQGCRYHGVTTASGETLPDPLDPTC-SLCTCQEGSM-RCQKKPCPPALCPHPSPGPCF 830
Query: 1305 CVAVGSSTCQASGDPHYTTFDGRRFDF-MGTCVYVLAQ 1341
C S C + G H DG F+ G+C + Q
Sbjct: 831 CPVCHS--CLSQGREHQ---DGEEFEGPAGSCEWCRCQ 863
Score = 40.0 bits (92), Expect = 0.017
Identities = 65/256 (25%), Positives = 77/256 (30%), Gaps = 71/256 (27%)
Query: 1101 CGATEPGDC-PKLDSL--VAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRC 1157
C GDC P D + + S E DP+ P C G C C
Sbjct: 704 CPFPARGDCCPDCDGCEYLGESYLSNQE---FPDPREPCNLCTCL----GGFVTCGRRPC 756
Query: 1158 LLPGQSGPLCDA--LATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYG------ 1209
PG S PL + C+ G T S E P P C G
Sbjct: 757 EPPGCSHPLIPSGHCCPTCQGCRYHGVTT---ASGETLPDPLDPTCSLCTCQEGSMRCQK 813
Query: 1210 --CPLSCGDLPVPGGCGSE-CH----------------------EGCVCDEG-FALSGES 1243
CP + P PG C CH E C C G +
Sbjct: 814 KPCPPALCPHPSPGPCFCPVCHSCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQ 873
Query: 1244 CLPL---------ASC-----GCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSS 1289
C PL SC GC+ G HP G + P S C C E G+V+C
Sbjct: 874 CPPLPCKLQVTERGSCCPRCRGCLAHGEEHPEGSRWVPPDSACSSCVCHE-GVVTCARIQ 932
Query: 1290 C---------GPHEAC 1296
C GPH+ C
Sbjct: 933 CISSCAQPRQGPHDCC 948
Score = 38.1 bits (87), Expect = 0.063
Identities = 30/97 (30%), Positives = 39/97 (40%), Gaps = 15/97 (15%)
Query: 1217 LPVPGGCGS-ECHEGCV-CDEGFALSG--------ESCLPLASCGCVHQGTYHPPGQTFY 1266
+P C S CHEG V C +S C P S C H+G + PG++F
Sbjct: 910 VPPDSACSSCVCHEGVVTCARIQCISSCAQPRQGPHDCCPQCS-DCEHEGRKYEPGESFQ 968
Query: 1267 PGPGCDSLCHCQ---EG-GLVSCESSSCGPHEACQPS 1299
PG +C C+ EG + C C C PS
Sbjct: 969 PGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPS 1005
Score = 37.0 bits (84), Expect = 0.14
Identities = 55/194 (28%), Positives = 70/194 (36%), Gaps = 38/194 (19%)
Query: 1132 PKGPFREC-----HSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHP 1186
P P R C H + + C Y LPG P+CD C G
Sbjct: 209 PGDPCRICRCLEGHIQCRQRECASLCPYPARPLPGTCCPVCDG-------CFLNG---RE 258
Query: 1187 WRSEELCPL-SCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCL 1245
RS E P+ S P SH C+ G + C LP P C + G+ C
Sbjct: 259 HRSGE--PVGSGDPCSHCR-CANGS-VQCEPLPCPP---------VPCRHPGKIPGQCC- 304
Query: 1246 PLASCGCVHQGTYHPPGQTF-YPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLG 1304
P+ GC +QG + +TF G C CQ G VSCE C P+ G
Sbjct: 305 PVCD-GCEYQGHQYQSQETFRLQERGLCVRCSCQAGE-VSCEEQECPVTPCALPASGRQL 362
Query: 1305 CVAVGSSTCQASGD 1318
C A C+ G+
Sbjct: 363 CPA-----CELDGE 371
Score = 35.4 bits (80), Expect = 0.41
Identities = 63/240 (26%), Positives = 79/240 (32%), Gaps = 55/240 (22%)
Query: 1088 AFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQG 1147
A G W+ + RP PK CG + P P C P G
Sbjct: 374 AEGVQWEPDGRPCTACVCQDGVPK--------------CGAVLCPPAP---CQHPTQPPG 416
Query: 1148 AV----RDCVY-DRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCP-PHS 1201
A C Y + GQ+ D+ +A CQ T + P +C P S
Sbjct: 417 ACCPSCDSCTYHSQVYANGQNFTDADS-PCHACHCQDGTVTCS---LVDCPPTTCARPQS 472
Query: 1202 HYEACSYGCPLSC---GDLPVPGGCGSE----CHEGCVCDEGFA---------------L 1239
C CP C ++ V G S C E C C EG A L
Sbjct: 473 GPGQCCPRCP-DCILEEEVFVDGESFSHPRDPCQE-CRCQEGHAHCQPRPCPRAPCAHPL 530
Query: 1240 SGESCLPLASCGCVHQGTYHPPGQTF-YPGPGCDSLCHCQEGGLVSCESSSCGPHEACQP 1298
G +C P GC G +P G F +P C LC C G V C + C P +P
Sbjct: 531 PG-TCCPNDCSGCAFGGKEYPSGADFPHPSDPC-RLCRCLSGN-VQCLARRCVPLPCPEP 587
Score = 34.7 bits (78), Expect = 0.70
Identities = 39/152 (25%), Positives = 52/152 (34%), Gaps = 35/152 (23%)
Query: 775 LCRGLSAYAQACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSCN----GAAAPS 830
LCR LS Q + + P P+ P C P CP GAA
Sbjct: 564 LCRCLSGNVQCLARRCVPL-----PCPEPVLLPGE-----CCPQCPAPAGCPRPGAAHAR 613
Query: 831 NCS-----GRPCVEGCVCLPGFVASGGACVPASSC-------------GCTFQGLQLAPG 872
+ G PC C+CL G V+ P + C GC +QG + A G
Sbjct: 614 HQEYFSPPGDPC-RRCLCLDGSVSCQRLPCPPAPCAHPRQGPCCPSCDGCLYQGKEFASG 672
Query: 873 QEVWADELCQRRCTCNGATHQVTCRDKQSCPA 904
+ + C C + V+C K PA
Sbjct: 673 ERFPSPTAACHLCLCWEGS--VSCEPKACAPA 702
Score = 33.9 bits (76), Expect = 1.2
Identities = 49/184 (26%), Positives = 67/184 (36%), Gaps = 42/184 (22%)
Query: 796 WRSPANC-PLSC-PANSRYELCGPACPTSCNGAA--APSNCSGR-------PCVEGCVCL 844
W +C P +C PA + G CP C+G S S + PC C CL
Sbjct: 688 WEGSVSCEPKACAPALCPFPARGDCCP-DCDGCEYLGESYLSNQEFPDPREPC-NLCTCL 745
Query: 845 PGFVASG----------------GACVPASSCGCTFQGLQLAPGQEV--WADELCQRRCT 886
GFV G G C P GC + G+ A G+ + D C CT
Sbjct: 746 GGFVTCGRRPCEPPGCSHPLIPSGHCCPTCQ-GCRYHGVTTASGETLPDPLDPTCS-LCT 803
Query: 887 CNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDF-MG 945
C + + C+ K+ CP G C+ +C G H DG F+ G
Sbjct: 804 CQEGS--MRCQ-KKPCPPALCPHPSPG--PCFCPVCHSCLSQGREHQ---DGEEFEGPAG 855
Query: 946 TCTY 949
+C +
Sbjct: 856 SCEW 859
>gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]
Length = 2639
Score = 180 bits (456), Expect = 1e-44
Identities = 137/466 (29%), Positives = 206/466 (44%), Gaps = 57/466 (12%)
Query: 837 CVEGCVCLPGFVASG-GACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVT 895
CV GCVC G + G G CV C C + G ++ D CN T
Sbjct: 697 CVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVD--------CN------T 742
Query: 896 CRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGS- 954
C +C G Q C+ GTC G HY++FDG+ +DF G C+Y+ V
Sbjct: 743 C----TCKRGRWVCTQ---AVCH----GTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDY 791
Query: 955 CGQNAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPF 1014
CGQN++L +F ++ EN G+ V+ ++A+++ ++ + ++ V+ D ++ +
Sbjct: 792 CGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHR-VVIQRDEGHHVAY 850
Query: 1015 QAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADD 1074
+ G+ VV + G+ V +D V K+ SY +CGLCGNF+ +D
Sbjct: 851 TTRE-------VGQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNND 903
Query: 1075 LALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKG 1134
R ++ L FGNSW+E +T P C ++ ++ +C IL
Sbjct: 904 FTTRDHMVVSSELDFGNSWKEAPTCPDVSTNPEPCSLNPH---RRSWAEKQCSIL--KSS 958
Query: 1135 PFRECHSKLDPQGAVRDCVYDRCLLP--GQSGPLCDALATYAAACQAAGATVHPWRSEEL 1192
F CHSK+DP+ CV+D C G C A+A+YA C GA V WR+ +L
Sbjct: 959 VFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACVF-WRTPDL 1017
Query: 1193 CPLSC----PPHS---HYEACSYGCPLSCGDL-PVPGGCGSECHEGCV--CDEGFALSGE 1242
CP+ C PPH HYE C +C + + EGC C + + E
Sbjct: 1018 CPIFCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEE 1077
Query: 1243 ---SCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSC 1285
C+ CGC + T++PPG + C S C C V C
Sbjct: 1078 DLKKCVTADKCGCYVEDTHYPPGASVPTEETCKS-CVCTNSSQVVC 1122
Score = 160 bits (404), Expect = 1e-38
Identities = 118/404 (29%), Positives = 178/404 (44%), Gaps = 39/404 (9%)
Query: 516 CQVVGGKAGCV-AESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVE-LCSEDDTLPAFS 573
C G+ C A C G HY TFDG+ YD G CSY V+ C ++ +L +FS
Sbjct: 743 CTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFS 802
Query: 574 VEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQ 633
+ +N G+ V+ S ++ + G L D + R+ + EG Y
Sbjct: 803 IITENVPCGTTGVTC---------SKAIKIFMGRTELKLED--KHRVVIQRDEGHHVAYT 851
Query: 634 S---GPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGAL 690
+ G VVE G++V +D + + L ++ VCGLCGN++ +DF T D +
Sbjct: 852 TREVGQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMV 911
Query: 691 APDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHD 750
++F +SWK C D N P C+ + ++ C +L F++CH
Sbjct: 912 VSSELDFGNSWKEAP---TCPDVSTNPEP-CSLNPHRRSWAEKQCSILK--SSVFSICHS 965
Query: 751 TLDPRPFLEQCVYDLCV--VGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSC-- 806
+DP+PF E CV+D C GG+ C +++YAQ C + G V WR+P CP+ C
Sbjct: 966 KVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACV-FWRTPDLCPIFCDY 1024
Query: 807 -----PANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCV--C---LPGFVASGGACVP 856
YE CG +C + +EGC C P + CV
Sbjct: 1025 YNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVT 1084
Query: 857 ASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQ 900
A CGC + PG V +E C + C C ++ QV CR ++
Sbjct: 1085 ADKCGCYVEDTHYPPGASVPTEETC-KSCVCTNSS-QVVCRPEE 1126
Score = 138 bits (348), Expect = 3e-32
Identities = 126/429 (29%), Positives = 188/429 (43%), Gaps = 37/429 (8%)
Query: 510 CAAGQRCQVVGGKAGCVA--ESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDD 567
C+ G + V GC E C GDPHY TFDG Y G C+Y +VE S
Sbjct: 1916 CSNGLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEIS--P 1973
Query: 568 TLPAFSVEAKNEH-RGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSE 626
++ F V N H + +VS + VR + V + + + V Q +R V+L
Sbjct: 1974 SVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPY 2033
Query: 627 GR--LRVYQSGPRAVVEL-VFGLVVTYDWDCQLALSLP-ARFQDQVCGLCGNYNGDPADD 682
+ L VYQSG VV++ G++V+Y+ ++ LP RF + G CG +DD
Sbjct: 2034 KKYGLEVYQSGINYVVDIPELGVLVSYN-GLSFSVRLPYHRFGNNTKGQCGTCTNTTSDD 2092
Query: 683 FLTPDGALAPDAVEFASSWKLDDGD--YLCEDGCQNNCPACT-PGQAQ---HYE--GDRL 734
+ P G + + A W ++D + PA T PG + H + L
Sbjct: 2093 CILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPL 2152
Query: 735 CGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVG 794
C ++ D FA CH + P+ + + CV+D C + G L C L AYA C + I +
Sbjct: 2153 CQLIK--DSLFAQCHALVPPQHYYDACVFDSCFMPGSSLE-CASLQAYAALCAQQNICL- 2208
Query: 795 DWRSPAN--CPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFV-ASG 851
DWR+ + C + CP++ Y+ CGPA +C +++ N VEGC C G + +
Sbjct: 2209 DWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQN--NTVLVEGCFCPEGTMNYAP 2266
Query: 852 GACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQ 911
G V +CGC G P + E + C C + C+ K RCS Q
Sbjct: 2267 GFDVCVKTCGCV--GPDNVPREFGEHFEFDCKNCVCLEGGSGIICQPK-------RCS-Q 2316
Query: 912 NGLLGCYPD 920
+ C D
Sbjct: 2317 KPVTHCVED 2325
Score = 126 bits (317), Expect = 1e-28
Identities = 92/266 (34%), Positives = 123/266 (46%), Gaps = 31/266 (11%)
Query: 655 QLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKL-----DDGDYL 709
QL ++L Q QV GLCGN+NG DDF T G + FA++WK D D+L
Sbjct: 412 QLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKLDWL 471
Query: 710 CEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVG 769
+D C N + A+H+ C +L K + PF CH +DP + ++C YD C
Sbjct: 472 -DDPCSLNIESAN--YAEHW-----CSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQ 523
Query: 770 GERLSLCRGLSAYAQACLELGISVGDWRSPANCPL---SCPANSRYELCGPACPTSCNG- 825
LC LS+YA+AC G+ + WR C SCP + + C +C
Sbjct: 524 NNEDCLCAALSSYARACTAKGVMLWGWREHV-CNKDVGSCPNSQVFLYNLTTCQQTCRSL 582
Query: 826 AAAPSNC-SGRPCVEGCVCLP-GFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQR 883
+ A S+C G V+GC C F+ G CVP + C C +GL L G V E
Sbjct: 583 SEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQE---E 639
Query: 884 RCTC-NGATHQVTCRD----KQSCPA 904
RC C +G H CR QSC A
Sbjct: 640 RCVCRDGRLH---CRQIRLIGQSCTA 662
Score = 119 bits (297), Expect = 3e-26
Identities = 121/456 (26%), Positives = 178/456 (39%), Gaps = 59/456 (12%)
Query: 886 TCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMG 945
TC+ V D C C CY C G GDPHYV+FDG + + G
Sbjct: 1915 TCSNGLQPVRVEDPDGCCWHWECD-------CY------CTGWGDPHYVTFDGLYYSYQG 1961
Query: 946 TCTYLLVGSCGQNAALPAFRVLVENEH---RGSQTVSYTRAVRVEARGVKVAVRREYPGQ 1002
CTY+LV + ++ F V ++N H + T VR E + V + P Q
Sbjct: 1962 NCTYVLVEEI--SPSVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQ 2019
Query: 1003 VLVDDVLQYLPFQAADGQVQVFRQGRDAVVR-TDFGLTVTYDWNARVTAKVP-SSYAEAL 1060
V V Q + ++V++ G + VV + G+ V+Y+ + ++P +
Sbjct: 2020 VQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVLVSYN-GLSFSVRLPYHRFGNNT 2078
Query: 1061 CGLCGNFNGDPADDLALRGGGQAANALAFGNSW--QEETRPGC----------GATEPG- 1107
G CG +DD L G +N A + W + ++P C T PG
Sbjct: 2079 KGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGG 2138
Query: 1108 --DCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGP 1165
P D + C ++ D F +CH+ + PQ CV+D C +PG S
Sbjct: 2139 GKTTPHKDCTPSPL------CQLIKD--SLFAQCHALVPPQHYYDACVFDSCFMPGSSLE 2190
Query: 1166 LCDALATYAAACQAAGATVHPWRSEE--LCPLSCPPHSHYEACSYGCPLSCGDLPVPGGC 1223
C +L YAA C + WR+ C + CP H Y+AC +C
Sbjct: 2191 -CASLQAYAALCAQQNICL-DWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQN- 2247
Query: 1224 GSECHEGCVCDEG---FALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEG 1280
+ EGC C EG +A + C + +CGCV G + P + C C EG
Sbjct: 2248 NTVLVEGCFCPEGTMNYAPGFDVC--VKTCGCV--GPDNVPREFGEHFEFDCKNCVCLEG 2303
Query: 1281 GL-VSCESSSCG--PHEACQPSGGSLGCVAVGSSTC 1313
G + C+ C P C G L + TC
Sbjct: 2304 GSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTC 2339
Score = 107 bits (266), Expect = 1e-22
Identities = 89/352 (25%), Positives = 139/352 (39%), Gaps = 34/352 (9%)
Query: 505 CEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCS 564
C + A G Q G VC G+ HY TFDG + G C Y C
Sbjct: 12 CLALSLAGGSELQTEGRTRN---HGHNVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCR 68
Query: 565 EDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEV----GFVLVDNQRSRL 620
+ F+V K + + V + + ++ LTR V + L
Sbjct: 69 --GSYKEFAVHLKRGPGQAEAPAGVESILLTIKDDTIYLTRHLAVLNGAVVSTPHYSPGL 126
Query: 621 PVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPA 680
+ S+ +VY GL + ++ + L L L +F++ CGLCG+YNG +
Sbjct: 127 LIEKSDAYTKVYSRA---------GLTLMWNREDALMLELDTKFRNHTCGLCGDYNGLQS 177
Query: 681 DDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPA-CTPGQAQHYEGDRLCGMLT 739
DG L +EF + K++ D +CED + PA C+ +A+ C L
Sbjct: 178 YSEFLSDGVLF-SPLEFGNMQKINQPDVVCEDPEEEVAPASCSEHRAE-------CERLL 229
Query: 740 KLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSP 799
+ FA C D + P+L C D C G +C ++ +++ C G G+WR+
Sbjct: 230 TAEA-FADCQDLVPLEPYLRACQQDRCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTA 288
Query: 800 AN-----CPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPG 846
+ +CP N Y G C +C+ S C ++GC C G
Sbjct: 289 TSAVSPGASKTCPGNLVYLESGSPCMDTCSHLEVSSLCEEHR-MDGCFCPEG 339
Score = 102 bits (254), Expect = 3e-21
Identities = 75/235 (31%), Positives = 97/235 (41%), Gaps = 27/235 (11%)
Query: 1062 GLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQ 1121
GLCGNFNG DD G A F N+W+ ++ C LD + ++
Sbjct: 427 GLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQS--SCH----DKLDWLDDPCSLNIE 480
Query: 1122 SKNE----CGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAAC 1177
S N C +L + PF CHS +DP + C YD C LC AL++YA AC
Sbjct: 481 SANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARAC 540
Query: 1178 QAAGATVHPWRSEELCPL---SCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHE----- 1229
A G + WR E +C SCP + C +C L S C E
Sbjct: 541 TAKGVMLWGWR-EHVCNKDVGSCPNSQVFLYNLTTCQQTCRSL---SEADSHCLEGFAPV 596
Query: 1230 -GCVC-DEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGL 1282
GC C D F C+PLA C C H+G Y G + C C++G L
Sbjct: 597 DGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQ---EERCVCRDGRL 648
Score = 82.0 bits (201), Expect = 4e-15
Identities = 76/271 (28%), Positives = 102/271 (37%), Gaps = 35/271 (12%)
Query: 1140 HSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCP- 1198
H+ LD +G C G D + C +H R L SC
Sbjct: 604 HTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEERCVCRDGRLH-CRQIRLIGQSCTA 662
Query: 1199 PHSHYE-------ACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGES-CLPLASC 1250
P H + A S LSC L G +EC GCVC +G G C+ C
Sbjct: 663 PKIHMDCSNLTALATSKPRALSCQTLAA-GYYHTECVSGCVCPDGLMDDGRGGCVVEKEC 721
Query: 1251 GCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGS 1310
CVH + G C++ C C+ G V + AV
Sbjct: 722 PCVHNNDLYSSGAKIKVD--CNT-CTCKRGRWVCTQ--------------------AVCH 758
Query: 1311 STCQASGDPHYTTFDGRRFDFMGTCVYVLAQT-CGTRPGLHRFAVLQENVAWGNGRVSVT 1369
TC G HY TFDG+ +DF G C YV Q CG L F+++ ENV G V+ +
Sbjct: 759 GTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVTCS 818
Query: 1370 RVITVQVANFTLRLEQRQWKVTVRADGEQGA 1400
+ I + + L+LE + V R +G A
Sbjct: 819 KAIKIFMGRTELKLEDKHRVVIQRDEGHHVA 849
Score = 79.3 bits (194), Expect = 2e-14
Identities = 75/323 (23%), Positives = 128/323 (39%), Gaps = 31/323 (9%)
Query: 925 CQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAV 984
C G+ HY +FDG F F G C Y C + F V ++ ++ + ++
Sbjct: 37 CSTWGNFHYKTFDGDVFRFPGLCDYNFASDC--RGSYKEFAVHLKRGPGQAEAPAGVESI 94
Query: 985 RVEARGVKVAVRREYPGQVLVDDVLQ---YLP---FQAADGQVQVFRQGRDAVVRTDFGL 1038
+ + + + R VL V+ Y P + +D +V+ + GL
Sbjct: 95 LLTIKDDTIYLTRHLA--VLNGAVVSTPHYSPGLLIEKSDAYTKVYSRA---------GL 143
Query: 1039 TVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETR 1098
T+ ++ + ++ + + CGLCG++NG + L G + L FGN Q+ +
Sbjct: 144 TLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFL-SDGVLFSPLEFGNM-QKINQ 201
Query: 1099 PGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCL 1158
P +P + + A + + EC L + F +C + + +R C DRC
Sbjct: 202 PDVVCEDPEE----EVAPASCSEHRAECERLLTAEA-FADCQDLVPLEPYLRACQQDRCR 256
Query: 1159 LPGQSGPLCDALATYAAACQAAGATVHPWRSEEL-----CPLSCPPHSHYEACSYGCPLS 1213
PG +C +A ++ C AG WR+ +CP + Y C +
Sbjct: 257 CPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDT 316
Query: 1214 CGDLPVPGGCGSECHEGCVCDEG 1236
C L V C +GC C EG
Sbjct: 317 CSHLEVSSLCEEHRMDGCFCPEG 339
Score = 46.2 bits (108), Expect = 2e-04
Identities = 24/64 (37%), Positives = 32/64 (50%), Gaps = 3/64 (4%)
Query: 1313 CQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWG-NGRVSVTRV 1371
C GDPHY TFDG + + G C YVL + P + F V +N N +VS R
Sbjct: 1941 CTGWGDPHYVTFDGLYYSYQGNCTYVLVEEIS--PSVDNFGVYIDNYHCDPNDKVSCPRT 1998
Query: 1372 ITVQ 1375
+ V+
Sbjct: 1999 LIVR 2002
Score = 37.0 bits (84), Expect = 0.14
Identities = 20/46 (43%), Positives = 22/46 (47%), Gaps = 2/46 (4%)
Query: 1309 GSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAV 1354
G + C G+ HY TFDG F F G C Y A C R FAV
Sbjct: 33 GHNVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDC--RGSYKEFAV 76
>gi|37693519 BMP-binding endothelial regulator precursor protein [Homo
sapiens]
Length = 685
Score = 172 bits (436), Expect = 2e-42
Identities = 141/497 (28%), Positives = 208/497 (41%), Gaps = 65/497 (13%)
Query: 802 CP-LSCPANSRYELCGPACPT-------------SC--------NGAA-APSNCSGRPCV 838
CP LSCP + + G CP SC NG++ NC+ C
Sbjct: 203 CPILSCPQHLSHIPPGQCCPKCLGQRKVFDLPFGSCLFRSDVYDNGSSFLYDNCTACTCR 262
Query: 839 EGCVCLPGFVASGGACVPASSCGCTFQGLQLAPGQ---------------EVWADELCQR 883
+ V + G C GC + L P + E+W+ C
Sbjct: 263 DSTVVCKRKCSHPGGCDQGQE-GCCEECLLRVPPEDIKVCKFGNKIFQDGEMWSSINCTI 321
Query: 884 RCTCNGATHQVTCRDKQ-----SCPAGERCSVQNGLLGCYP---DRFGTCQGSGDPHYVS 935
G T CR+KQ SCP G+ + + GC P ++ G C GDPHY +
Sbjct: 322 CACVKGRTE---CRNKQCIPISSCPQGKILNRK----GCCPICTEKPGVCTVFGDPHYNT 374
Query: 936 FDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAV 995
FDGR F+F GTC Y+L C A+ F+VLV+N+ R +++ S+T++V + +V++
Sbjct: 375 FDGRTFNFQGTCQYVLTKDCSSPAS--PFQVLVKNDARRTRSFSWTKSVELVLGESRVSL 432
Query: 996 RREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSS 1055
++ V + LP +A + + G V T GL +++D ++ V
Sbjct: 433 QQHLT--VRWNGSRIALPCRAPHFHIDL--DGYLLKVTTKAGLEISWDGDSFVEVMAAPH 488
Query: 1056 YAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPKL-DS 1114
LCGLCGN+NG DDL G + F SW+ E+ C + P+L
Sbjct: 489 LKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCNRPQRKPVPELCQG 548
Query: 1115 LVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYA 1174
V +L++ EC L + F+ CHS +D R CV D C P C++ Y
Sbjct: 549 TVKVKLRAHRECQKLKSWE--FQTCHSTVDYATFYRSCVTDMCECPVHKNCYCESFLAYT 606
Query: 1175 AACQAAGATVHPWRSEELCPLS-CPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVC 1233
ACQ G VH W ++ C + C + Y+ C GC +C + G C C GC C
Sbjct: 607 RACQREGIKVH-WEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGPCNKPCVAGCHC 665
Query: 1234 DEGFALSGESCLPLASC 1250
L C+ C
Sbjct: 666 PANLVLHKGRCIKPVLC 682
Score = 165 bits (418), Expect = 3e-40
Identities = 108/363 (29%), Positives = 155/363 (42%), Gaps = 18/363 (4%)
Query: 505 CEGMQCAAGQRC---QVVGGKAGC--VAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTM 559
C QC C +++ K C E VC GDPHY TFDGR ++ GTC Y +
Sbjct: 331 CRNKQCIPISSCPQGKILNRKGCCPICTEKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVL 390
Query: 560 VELCSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSR 619
+ CS + F V KN+ R +R S+ V + VSL + + V SR
Sbjct: 391 TKDCSSPAS--PFQVLVKNDARRTRSFSWTKSVELVLGESRVSLQQ----HLTVRWNGSR 444
Query: 620 LPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDP 679
+ + + G V GL +++D D + + + ++CGLCGNYNG
Sbjct: 445 IALPCRAPHFHIDLDGYLLKVTTKAGLEISWDGDSFVEVMAAPHLKGKLCGLCGNYNGHK 504
Query: 680 ADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQ-HYEGDRLCGML 738
DD + DG D +FA SW+++ ++ C + P G + R C L
Sbjct: 505 RDDLIGGDGNFKFDVDDFAESWRVESNEF-CNRPQRKPVPELCQGTVKVKLRAHRECQKL 563
Query: 739 TKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRS 798
+ F CH T+D F CV D+C + C AY +AC GI V W
Sbjct: 564 KSWE--FQTCHSTVDYATFYRSCVTDMCECPVHKNCYCESFLAYTRACQREGIKV-HWEP 620
Query: 799 PANCPLS-CPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPA 857
NC + C + Y+ CGP C +C+ C+ +PCV GC C V G C+
Sbjct: 621 QQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGPCN-KPCVAGCHCPANLVLHKGRCIKP 679
Query: 858 SSC 860
C
Sbjct: 680 VLC 682
Score = 74.3 bits (181), Expect = 8e-13
Identities = 72/252 (28%), Positives = 100/252 (39%), Gaps = 52/252 (20%)
Query: 1191 ELCP-LSCPPHSHYEACSYGCPLSCG-----DLPVPGGC--GSECHEG-----------C 1231
E+CP LSCP H + CP G DLP G C S+ ++ C
Sbjct: 201 EVCPILSCPQHLSHIPPGQCCPKCLGQRKVFDLPF-GSCLFRSDVYDNGSSFLYDNCTAC 259
Query: 1232 VCDEGFALSGESCLPLASC-----GCVHQGTYHPP----------GQTFYPGPGCDSL-- 1274
C + + C C GC + P + F G S+
Sbjct: 260 TCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVPPEDIKVCKFGNKIFQDGEMWSSINC 319
Query: 1275 --CHCQEGGLVSCESSSCGPHEACQPSGGSL---GCVAVGSS---TCQASGDPHYTTFDG 1326
C C +G C + C P +C P G L GC + + C GDPHY TFDG
Sbjct: 320 TICACVKGR-TECRNKQCIPISSC-PQGKILNRKGCCPICTEKPGVCTVFGDPHYNTFDG 377
Query: 1327 RRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQR 1386
R F+F GTC YVL + C + F VL +N A S T+ + + + + L+Q
Sbjct: 378 RTFNFQGTCQYVLTKDCSSPAS--PFQVLVKNDARRTRSFSWTKSVELVLGESRVSLQQH 435
Query: 1387 QWKVTVRADGEQ 1398
+TVR +G +
Sbjct: 436 ---LTVRWNGSR 444
Score = 34.7 bits (78), Expect = 0.70
Identities = 35/140 (25%), Positives = 47/140 (33%), Gaps = 33/140 (23%)
Query: 818 ACPTSCNGAAAPSN--------------CSGRPCVEGCVCLPGF---------VASGGAC 854
AC C G N C R C EG V G + G C
Sbjct: 100 ACCEQCKGCTYEGNTYNSSFKWQSPAEPCVLRQCQEGVVTESGVRCVVHCKNPLEHLGMC 159
Query: 855 VPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQ--------VTCRDKQS-CPAG 905
P GC F+G+Q G+E + +C+C G Q ++C S P G
Sbjct: 160 CPTCP-GCVFEGVQYQEGEEFQPEGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPG 218
Query: 906 ERCSVQNGLLGCYPDRFGTC 925
+ C G + FG+C
Sbjct: 219 QCCPKCLGQRKVFDLPFGSC 238
>gi|239755776 PREDICTED: similar to Mucin-19 [Homo sapiens]
Length = 1950
Score = 130 bits (327), Expect = 9e-30
Identities = 134/596 (22%), Positives = 225/596 (37%), Gaps = 74/596 (12%)
Query: 704 DDGDYLCEDGCQNNCPACTPGQAQHYE-GDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCV 762
D +++ +CP + E G + CG + L + + C+
Sbjct: 646 DINEHIANSKIPGDCPNAVGKSYEVCEDGIQKCGKVAALSNDYKMI------------CI 693
Query: 763 YDLCVVGGERLSLCRGLSAYAQACLELGISVGD-WRSPANCPLS---CPANSRYELCGPA 818
+ C ++ S C S ++ C G + WRS ++ CP Y+ CGP+
Sbjct: 694 DEYCQTR-DKTSTCDTYSELSRLCASDGPGTFESWRSDSDVVCETQRCPEQHIYKECGPS 752
Query: 819 CPTSCNGAAAPSNCSGRPCVEGCVCLPGF----VASGGACVPASSCGCTFQGLQLAPGQE 874
P +C+ A + CV GC C G+ + G CV + C C G PG+
Sbjct: 753 NPATCSNVAPFQDSE---CVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGEV 809
Query: 875 VWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYV 934
+ C +CTC A T + CP RC V+ L
Sbjct: 810 --REGPCGSQCTCQDAKWSCT---EALCPG--RCKVEGSSL------------------T 844
Query: 935 SFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVA 994
+FDG +++F G C +L V + ++ ++ + G+ S T + K
Sbjct: 845 TFDGVKYNFPGNCHFLAVHN--EDWSISVELRPCPSGQTGTCLNSVTLLLNSSVPVDKYV 902
Query: 995 VRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAV-VRTDFG--LTVTYDWNARVTAK 1051
+ + +D ++ + +D ++Q+F + V T F L + ++
Sbjct: 903 FNSD---GTVTNDKIRNQGYYYSD-KIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVS 958
Query: 1052 VPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPK 1111
+P + GLCG++N DD + AF NSW+ + C P C
Sbjct: 959 MPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMS---CPKGNPSSCIS 1015
Query: 1112 LDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALA 1171
++ ++ ++ CGIL D GP CH ++P+ +C C LC L
Sbjct: 1016 IE----KEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILG 1071
Query: 1172 TYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPV-PGGCGSE--CH 1228
Y AC + WR+ LC SCP ++ C SC L C E
Sbjct: 1072 NYVKACAEKETYIVGWRT-GLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPV 1130
Query: 1229 EGCVCDEGFALSGE-SCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLV 1283
+GC C + + E +C+ + C C PG+ + D+ C C++G L+
Sbjct: 1131 DGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHTD---DNKCVCRDGILL 1183
Score = 115 bits (287), Expect = 4e-25
Identities = 112/431 (25%), Positives = 170/431 (39%), Gaps = 55/431 (12%)
Query: 513 GQRCQVVGGKAGCV-AESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPA 571
G +C K C A C+ +G TTFDG +Y+ G C + V +ED ++
Sbjct: 815 GSQCTCQDAKWSCTEALCPGRCKVEGSS-LTTFDGVKYNFPGNCHFLAVH--NEDWSISV 871
Query: 572 FSVEAKNEHRGSRRVSYVGL----VTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEG 627
+ G+ S L V V Y + T V N + R
Sbjct: 872 ELRPCPSGQTGTCLNSVTLLLNSSVPVDKYVFNSDGT--------VTNDKIRNQGYYYSD 923
Query: 628 RLRVYQSGPRAV-VELVFG--LVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFL 684
+++++ + + VE F L + QL +S+P GLCG+YN DDF+
Sbjct: 924 KIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFM 983
Query: 685 TPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGP 744
+ L + FA+SW++ C G N +C + + + +R CG+L GP
Sbjct: 984 SSQNILEKTSQAFANSWEMMS----CPKG---NPSSCISIEKEKF-AERHCGILLDSSGP 1035
Query: 745 FAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPL 804
A CH ++P+P+ E+C C + LC L Y +AC E + WR+ C
Sbjct: 1036 LASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRT-GLCEH 1094
Query: 805 SCPANSRYELCGPACPTSCNGAAAPSNCSGRPC------VEGCVCLPGFVASG-GACVPA 857
SCP+ ++ AC +SC + R C V+GC C + G CV
Sbjct: 1095 SCPSGLVFKYNVKACNSSCRSLSE----RDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLK 1150
Query: 858 SSCGCTFQGLQLAPGQEVWADE----------LCQ-----RRCTCNGATHQVTCRD-KQS 901
S C C + PG+ + D+ LCQ C+G V C D K
Sbjct: 1151 SQCDCYINDEVMQPGKLIHTDDNKCVCRDGILLCQIPIDLTLQNCSGGAEYVDCSDPKAQ 1210
Query: 902 CPAGERCSVQN 912
CS +N
Sbjct: 1211 RRTNRTCSTRN 1221
Score = 110 bits (276), Expect = 8e-24
Identities = 83/252 (32%), Positives = 112/252 (44%), Gaps = 24/252 (9%)
Query: 1051 KVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCP 1110
K+ ++ +CGLCGN NGD DD R A+ AL FGNSW +T C T P
Sbjct: 1255 KIIVAFQGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSW--KTSQECSDTVAQTFP 1312
Query: 1111 KLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCL--LPGQSGPLCD 1168
DS + + +C IL D FR+CH+K+DP C+ + C + G+ C
Sbjct: 1313 -CDSNPYCKAWAVRKCEILRD--STFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCT 1369
Query: 1169 ALATYAAACQAAGATVHPWRSEELCPLSCPPHS-------HYEACSYGCPLSCGDLPVPG 1221
A+A YA AC A G V WR LCP+ C ++ HYE C +C D V G
Sbjct: 1370 AVAMYAEACSAVGVCV-SWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLV-G 1427
Query: 1222 GCGSECHEGCV--CDEGFALSGES---CLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCH 1276
S EGC C + E+ C+ L+ C C + P G C C+
Sbjct: 1428 QKFSSLLEGCYAKCPDSAPYLDENTMKCVSLSECSCFYNDVI-PAGGVI--EDNCGRTCY 1484
Query: 1277 CQEGGLVSCESS 1288
C G L E++
Sbjct: 1485 CIAGQLECSETA 1496
Score = 108 bits (271), Expect = 3e-23
Identities = 76/238 (31%), Positives = 103/238 (43%), Gaps = 26/238 (10%)
Query: 664 FQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTP 723
FQ +VCGLCGN NGD DDF T ++A A+EF +SWK C D P C
Sbjct: 1260 FQGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQE---CSDTVAQTFP-CDS 1315
Query: 724 GQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCV--VGGERLSLCRGLSA 781
R C +L D F CH+ +DP + + C+ + C + G+ L C ++
Sbjct: 1316 NPYCKAWAVRKCEILR--DSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAM 1373
Query: 782 YAQACLELGISVGDWRSPANCPLSC-----PANSR--YELCGPACPTSCNGAAAPSNCSG 834
YA+AC +G+ V WR P CP+ C P R YE CG +C S
Sbjct: 1374 YAEACSAVGVCV-SWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQKFSS 1432
Query: 835 RPCVEGCVC-----LPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTC 887
+EGC P + CV S C C + + A G ++ C R C C
Sbjct: 1433 --LLEGCYAKCPDSAPYLDENTMKCVSLSECSCFYNDVIPAGGV---IEDNCGRTCYC 1485
Score = 75.5 bits (184), Expect = 4e-13
Identities = 71/271 (26%), Positives = 105/271 (38%), Gaps = 47/271 (17%)
Query: 1077 LRGGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSK-NECGILADPKGP 1135
+ GG + N Q+ + PGDCP + + +CG +A
Sbjct: 628 IESGGDFNIEIKRNNDRQDINEHIANSKIPGDCPNAVGKSYEVCEDGIQKCGKVAALSND 687
Query: 1136 FRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAG-ATVHPWRSEE--L 1192
++ C+ + C ++ CD + + C + G T WRS+ +
Sbjct: 688 YKMI------------CIDEYCQTRDKTST-CDTYSELSRLCASDGPGTFESWRSDSDVV 734
Query: 1193 CPLS-CPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALS--GE--SCLPL 1247
C CP Y+ C P +C + V SEC GC C EG+ L GE C+
Sbjct: 735 CETQRCPEQHIYKECGPSNPATCSN--VAPFQDSECVSGCTCPEGYLLDDIGEKGKCVLK 792
Query: 1248 ASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVA 1307
A C C GT + PG+ GP C S C CQ+ SC + C C+ G SL
Sbjct: 793 AECPCESSGTVYQPGEV-REGP-CGSQCTCQDAKW-SCTEALCPGR--CKVEGSSL---- 843
Query: 1308 VGSSTCQASGDPHYTTFDGRRFDFMGTCVYV 1338
TTFDG +++F G C ++
Sbjct: 844 --------------TTFDGVKYNFPGNCHFL 860
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.428
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 63,631,425
Number of Sequences: 37866
Number of extensions: 3284580
Number of successful extensions: 10488
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 48
Number of HSP's successfully gapped in prelim test: 209
Number of HSP's that attempted gapping in prelim test: 7696
Number of HSP's gapped (non-prelim): 1606
length of query: 1472
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1357
effective length of database: 13,892,928
effective search space: 18852703296
effective search space used: 18852703296
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.