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Search of human proteins with 239757282
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239757282 PREDICTED: similar to Fc fragment of IgG binding
protein [Homo sapiens]
(1403 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239757282 PREDICTED: similar to Fc fragment of IgG binding pr... 3034 0.0
gi|239751787 PREDICTED: hypothetical protein XP_002348012 [Homo ... 2930 0.0
gi|154146262 Fc fragment of IgG binding protein [Homo sapiens] 2930 0.0
gi|239757286 PREDICTED: similar to Fc fragment of IgG binding pr... 753 0.0
gi|134268640 tectorin alpha precursor [Homo sapiens] 731 0.0
gi|16554449 zonadhesin isoform 3 [Homo sapiens] 686 0.0
gi|27881494 zonadhesin isoform 6 [Homo sapiens] 686 0.0
gi|239757284 PREDICTED: similar to Fc fragment of IgG binding pr... 546 e-155
gi|169202626 PREDICTED: similar to mucin 5, partial [Homo sapiens] 362 2e-99
gi|134031945 SCO-spondin [Homo sapiens] 357 4e-98
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens] 355 1e-97
gi|161019170 mucin 5AC [Homo sapiens] 346 8e-95
gi|89191868 von Willebrand factor preproprotein [Homo sapiens] 308 2e-83
gi|116284392 mucin 2 precursor [Homo sapiens] 304 3e-82
gi|239755901 PREDICTED: chromosome 12 open reading frame 64 [Hom... 303 6e-82
gi|239750386 PREDICTED: chromosome 12 open reading frame 64 [Hom... 303 6e-82
gi|239744688 PREDICTED: hypothetical protein LOC283310 [Homo sap... 303 6e-82
gi|239755545 PREDICTED: otogelin isoform 1 [Homo sapiens] 297 4e-80
gi|239755543 PREDICTED: otogelin isoform 2 [Homo sapiens] 297 4e-80
gi|239749989 PREDICTED: otogelin isoform 2 [Homo sapiens] 297 4e-80
gi|239749987 PREDICTED: otogelin isoform 1 [Homo sapiens] 297 4e-80
gi|239744300 PREDICTED: otogelin isoform 2 [Homo sapiens] 297 4e-80
gi|239744298 PREDICTED: otogelin isoform 1 [Homo sapiens] 297 4e-80
gi|151301154 mucin 6, gastric [Homo sapiens] 281 3e-75
gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens] 208 3e-53
gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens] 205 3e-52
gi|37693519 BMP-binding endothelial regulator precursor protein ... 185 3e-46
gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo ... 144 6e-34
gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo ... 144 6e-34
gi|239755776 PREDICTED: similar to Mucin-19 [Homo sapiens] 134 8e-31
>gi|239757282 PREDICTED: similar to Fc fragment of IgG binding protein
[Homo sapiens]
Length = 1403
Score = 3034 bits (7867), Expect = 0.0
Identities = 1403/1403 (100%), Positives = 1403/1403 (100%)
Query: 1 MRTLECGLACSNPQIPGTDWVDMEGAAMLYNGQPLKVLLPLLSPDPCHGVTCRPQETCKE 60
MRTLECGLACSNPQIPGTDWVDMEGAAMLYNGQPLKVLLPLLSPDPCHGVTCRPQETCKE
Sbjct: 1 MRTLECGLACSNPQIPGTDWVDMEGAAMLYNGQPLKVLLPLLSPDPCHGVTCRPQETCKE 60
Query: 61 QGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLTPFTVT 120
QGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLTPFTVT
Sbjct: 61 QGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLTPFTVT 120
Query: 121 TKNENRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGA 180
TKNENRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGA
Sbjct: 121 TKNENRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGA 180
Query: 181 SKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIP 240
SKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIP
Sbjct: 181 SKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIP 240
Query: 241 IWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPP 300
IWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPP
Sbjct: 241 IWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPP 300
Query: 301 ESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEV 360
ESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEV
Sbjct: 301 ESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEV 360
Query: 361 CGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEA 420
CGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEA
Sbjct: 361 CGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEA 420
Query: 421 GSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDP 480
GSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDP
Sbjct: 421 GSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDP 480
Query: 481 HYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYN 540
HYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYN
Sbjct: 481 HYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYN 540
Query: 541 HSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLR 600
HSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLR
Sbjct: 541 HSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLR 600
Query: 601 VPAAYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQE 660
VPAAYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQE
Sbjct: 601 VPAAYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQE 660
Query: 661 SFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQ 720
SFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQ
Sbjct: 661 SFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQ 720
Query: 721 AAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFV 780
AAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFV
Sbjct: 721 AAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFV 780
Query: 781 LSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECR 840
LSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECR
Sbjct: 781 LSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECR 840
Query: 841 LEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLE 900
LEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLE
Sbjct: 841 LEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLE 900
Query: 901 KNAAGDLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGL 960
KNAAGDLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGL
Sbjct: 901 KNAAGDLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGL 960
Query: 961 RLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGS 1020
RLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGS
Sbjct: 961 RLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGS 1020
Query: 1021 SKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDL 1080
SKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDL
Sbjct: 1021 SKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDL 1080
Query: 1081 CAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAA 1140
CAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAA
Sbjct: 1081 CAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAA 1140
Query: 1141 LSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSC 1200
LSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSC
Sbjct: 1141 LSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSC 1200
Query: 1201 SSSSGLTCQAAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYE 1260
SSSSGLTCQAAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYE
Sbjct: 1201 SSSSGLTCQAAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYE 1260
Query: 1261 LSSRCPGLQNTIPWYRVVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDL 1320
LSSRCPGLQNTIPWYRVVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDL
Sbjct: 1261 LSSRCPGLQNTIPWYRVVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDL 1320
Query: 1321 PAEKLASVSVSRTPDGSLLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQT 1380
PAEKLASVSVSRTPDGSLLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQT
Sbjct: 1321 PAEKLASVSVSRTPDGSLLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQT 1380
Query: 1381 NDWHDSQEKPAMEKWRAQDFSPW 1403
NDWHDSQEKPAMEKWRAQDFSPW
Sbjct: 1381 NDWHDSQEKPAMEKWRAQDFSPW 1403
>gi|239751787 PREDICTED: hypothetical protein XP_002348012 [Homo
sapiens]
Length = 3003
Score = 2930 bits (7596), Expect = 0.0
Identities = 1357/1373 (98%), Positives = 1361/1373 (99%), Gaps = 2/1373 (0%)
Query: 33 QPLKVLLPLLSPDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFD 92
QP +L ++ DPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFD
Sbjct: 1631 QPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFD 1690
Query: 93 FQGTCNYVLATTGCLGVSTQGLTPFTVTTKNENRGNPAVSYVRVVTVAALGTNISIHKDE 152
FQGTCNYVLATTGC GVSTQGLTPFTVTTKN+NRGNPAVSYVRVVTVAALGTNISIHKDE
Sbjct: 1691 FQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDE 1750
Query: 153 IGKVRV--NGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYH 210
IGKVRV NGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYH
Sbjct: 1751 IGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYH 1810
Query: 211 GAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDR 270
GAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDR
Sbjct: 1811 GAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDR 1870
Query: 271 LEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVA 330
LEQYEGPGFCGPLA GTGGPFTTCHAHVPPESFFKGCVLDVCMGGGD DILCKALASYVA
Sbjct: 1871 LEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVA 1930
Query: 331 ACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQ 390
ACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQ
Sbjct: 1931 ACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQ 1990
Query: 391 CDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASC 450
CDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASC
Sbjct: 1991 CDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASC 2050
Query: 451 GLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLG 510
GLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLG
Sbjct: 2051 GLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLG 2110
Query: 511 AENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLL 570
AENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLL
Sbjct: 2111 AENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLL 2170
Query: 571 HAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGK 630
HAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGK
Sbjct: 2171 HAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGK 2230
Query: 631 PAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQY 690
PAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQY
Sbjct: 2231 PAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQY 2290
Query: 691 FQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGD 750
FQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGD
Sbjct: 2291 FQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGD 2350
Query: 751 SCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPG 810
SCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPG
Sbjct: 2351 SCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPG 2410
Query: 811 PECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGR 870
PECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGR
Sbjct: 2411 PECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGR 2470
Query: 871 VYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVSLAQGQQVTVD 930
VYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVSLAQGQQVTVD
Sbjct: 2471 VYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVSLAQGQQVTVD 2530
Query: 931 GEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFN 990
GEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFN
Sbjct: 2531 GEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFN 2590
Query: 991 GNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEGCGPQGCPVCLAEETAPYESNEAC 1050
GNWSDDFVLPNGSAASSVETFGAAWR PGSSKGCGEGCGPQGCPVCLAEETAPYESNEAC
Sbjct: 2591 GNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEAC 2650
Query: 1051 GQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKP 1110
GQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKP
Sbjct: 2651 GQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKP 2710
Query: 1111 WRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIP 1170
WRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIP
Sbjct: 2711 WRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIP 2770
Query: 1171 VQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWA 1230
VQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWA
Sbjct: 2771 VQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWA 2830
Query: 1231 TRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEA 1290
TRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEA
Sbjct: 2831 TRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEA 2890
Query: 1291 VGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQVWL 1350
VGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQVWL
Sbjct: 2891 VGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQVWL 2950
Query: 1351 GANGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHDSQEKPAMEKWRAQDFSPW 1403
GANGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHDSQEKPAMEKWRAQDFSPW
Sbjct: 2951 GANGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHDSQEKPAMEKWRAQDFSPW 3003
Score = 1024 bits (2648), Expect = 0.0
Identities = 554/1435 (38%), Positives = 776/1435 (54%), Gaps = 90/1435 (6%)
Query: 41 LLSP--DPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCN 98
+LSP C G+ C + C+ GG+ C+ A C GDPHY +FDGR++D GTC+
Sbjct: 436 VLSPVEPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCS 495
Query: 99 YVLATTGCLGVSTQGLTPFTVTTKNENRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRV 158
Y + L L F+V KNE+RG+ VSYV +VTV A ++S+ + E+G V V
Sbjct: 496 YTMVE---LCSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLV 552
Query: 159 NGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCG 218
+ + LPVS+++GR+ V Q +A++ FGL V+YDW+ ++ ++LP+ + VCGLCG
Sbjct: 553 DNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCG 612
Query: 219 NMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPG 278
N + +P +D + P+G LAP + SW+ D LC D C+ +CP C + + YEG
Sbjct: 613 NYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDR 672
Query: 279 FCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVV 338
CG L GPF CH + P F + CV D+C+ GG+ LC+ L++Y AC G+
Sbjct: 673 LCGMLTK-LDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGIS 731
Query: 339 IEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEG-PCVEGCQCDAGFVL 397
+ DWR+ C ++CP NS YE+CGP CP SC A P+ C G PCVEGC C GFV
Sbjct: 732 VGDWRSPANCPLSCPANSRYELCGPACPTSCNGAA---APSNCSGRPCVEGCVCLPGFVA 788
Query: 398 SADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPA-SCGLGEVC 456
S CVP ++ CGC G G E WAD C + C C + C SC GE C
Sbjct: 789 SGGACVPASS-CGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERC 847
Query: 457 GLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTV 516
+ +G GC P CQ GDPHYV+ DG RFDF GTC YLL C G F V
Sbjct: 848 SV-QNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSC-GQNAALPAFRV 905
Query: 517 TVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQL-DSLLHAHLS 575
V NEHRGSQ VSYTR+V ++ + + +P ++ VD V LPFQ D +
Sbjct: 906 LVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQ 965
Query: 576 GADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAG-- 633
G D VV T GL++ +D ++ V +VP++YA +LCGLCGN+N DPADDL GG A
Sbjct: 966 GRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANA 1025
Query: 634 ------WQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPP 687
WQ GCG CP + Q+ + CG+++ GP CH + P
Sbjct: 1026 LAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQ-LQSKNECGILADPKGPFRECHSKLDP 1084
Query: 688 AQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYEL 747
+ C+ D C + G G LC A+ATY AACQAAGA + WR + CPL CP HSHYE
Sbjct: 1085 QGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEA 1144
Query: 748 CGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVF 807
C CP+SC L P GC S C EGCVCD GF LSG++C+P+ CGC+H G Y+P G+ F
Sbjct: 1145 CSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTF 1204
Query: 808 YPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITL 867
YPGP C+ C C GG V+C E ++CGPHE C+ G C A G C A+G HY T
Sbjct: 1205 YPGPGCDSLCHCQEGGLVSC-ESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTF 1263
Query: 868 DGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGD-----LQRLLVTVAGQVVSLA 922
DGR +D G+C YVLAQ C +PG F+++ E A G+ + + V VA + L
Sbjct: 1264 DGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLE 1323
Query: 923 QGQ-QVTVDGEAVALPV--AVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFR 979
Q Q +VTV+G + LPV A G++R + G ++V++T GLR+ +D ++ +++P +
Sbjct: 1324 QRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYY 1383
Query: 980 GRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWR--VPGSSKGCGEGCGPQGCPVCL 1037
++CGLCGN+NG+ DDF PNGS A + FG +W VP S C P G C+
Sbjct: 1384 QQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPC-PPGSEDCI 1442
Query: 1038 AEETAP------YESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLC 1091
P Y+ E CG L +P GP ++C ++ P + C++DLC G+ + LC
Sbjct: 1443 PSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILC 1502
Query: 1092 RSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRC 1151
++ AY +ACQAAG V+PWRT++FCP+ CP +SHY +C TC C+ALS C C
Sbjct: 1503 SNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGC 1562
Query: 1152 FEGCECDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAA 1211
EGC+CD FL + C+P+Q CGC HNG Y ++L +C ++C+C + G+ CQ
Sbjct: 1563 AEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEH 1622
Query: 1212 GCPPGRVCEVKAEARNC-------------------WATRGLCVLSVGA--------NLT 1244
C PG+VC+ +C +G+C+ + A +
Sbjct: 1623 SCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYH 1682
Query: 1245 TFDGARGATTSPGVYELSSR-CPGL--QNTIPWYRVVAEVQICHGKTEAVGQVHIFFQDG 1301
+FDG + Y L++ CPG+ Q P + V + Q + AV V +
Sbjct: 1683 SFDGRKFDFQGTCNYVLATTGCPGVSTQGLTP-FTVTTKNQ--NRGNPAVSYVRVVTVAA 1739
Query: 1302 MVT-LTPNKG------VWVNGLRVDLPAEKL-ASVSVSRTPDGSLLVRQKAGVQVWLGAN 1353
+ T ++ +K V VNG+ LP +SV++ +LLV G+QV N
Sbjct: 1740 LGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVAD-FGLQVSYDWN 1798
Query: 1354 GKVAVIVSNDHAGKLCGACGNFDGDQTND--WHDSQEKPAME----KWRAQDFSP 1402
+V V + + + G +CG CGN D + ND + + P++ WRA + P
Sbjct: 1799 WRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDP 1853
Score = 892 bits (2306), Expect = 0.0
Identities = 520/1420 (36%), Positives = 726/1420 (51%), Gaps = 129/1420 (9%)
Query: 47 CHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGC 106
C +C P E C+ GG C+ +TC GDPHY +FDGR+FDF GTC YVLA T C
Sbjct: 1224 CESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQT-C 1282
Query: 107 LGVSTQGLTPFTVTTKNENRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALP 166
+ GL F V +N GN VS RV+TV + + + + KV VNGV LP
Sbjct: 1283 --GTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQ-WKVTVNGVDMKLP 1339
Query: 167 VSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNN 226
V +A+G+I +Q S ++ DFGL+V+YD + V VT+P +Y+ +CGLCGN + +P +
Sbjct: 1340 VVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKD 1399
Query: 227 DQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPT----------CPEDRLEQYEG 276
D PNG+ A + +G SW D C CP CP + ++Y+
Sbjct: 1400 DFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPT--PCPPGSEDCIPSHKCPPELEKKYQK 1457
Query: 277 PGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAG 336
FCG L+ TG P ++CH V P+ K C+ D+C+GGG+ ILC + +YV+ACQAAG
Sbjct: 1458 EEFCGLLSSPTG-PLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAG 1516
Query: 337 VVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFV 396
+E WR + C + CP NSHYE+C C C + L+ P C+ C EGCQCD+GF+
Sbjct: 1517 GHVEPWRTETFCPMECPPNSHYELCADTCSLGCSA---LSAPPQCQDGCAEGCQCDSGFL 1573
Query: 397 LSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCG------------------- 437
+ CVP+ CGC+ NG Y+E D C Q C C
Sbjct: 1574 YNGQACVPIQQ-CGCYHNGVYYEPEQTVLIDN-CRQQCTCHAGKGMVCQEHSCKPGQVCQ 1631
Query: 438 PGGGSLVCTP------ASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFD 491
P GG L C +C E C GQ C P A C WGDPHY + DG +FD
Sbjct: 1632 PSGGILSCVTKDPCHGVTCRPQETC-KEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFD 1690
Query: 492 FQGTCEYLLSAP-CHG-PPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARW 549
FQGTC Y+L+ C G G FTVT N++RG+ AVSY R VT+ ++++
Sbjct: 1691 FQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDE 1750
Query: 550 PRKLQ--VDGVFVALPFQL-DSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYA 606
K++ V+GV ALP + D + + ++ GL +++D + V + +P++Y
Sbjct: 1751 IGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYH 1810
Query: 607 ASLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQG-CGECVSKPCPSPCTPE 657
++CGLCGN +++P +D G A W+ G C + CP+ C +
Sbjct: 1811 GAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPT-CPED 1869
Query: 658 QQESFGGPDACG-VISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYV 716
+ E + GP CG + S T GP CH VPP +F+GC+LD C G LC A+A+YV
Sbjct: 1870 RLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYV 1929
Query: 717 AACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPS---LSAPEGCESACREGC 773
AACQAAG + +WR C + CP +SHYE+CG CP SCPS L+ P CE C EGC
Sbjct: 1930 AACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGC 1989
Query: 774 VCDAGFVLSGDTCVPVGQ-CGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAA 832
CDAGFVLS D CVP+ CGC +G Y+ G F+ C + C CGPGG A+
Sbjct: 1990 QCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPAS 2049
Query: 833 CGPHEEC-RLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKP- 890
CG E C L G C C A G HY+TLDG +D G+C Y+L+ CH P
Sbjct: 2050 CGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPL 2109
Query: 891 GDEDFSIVLEKNAAGDLQ-------RLLVTVAGQVVSLAQGQQVTVDGEAVALPVAV-GR 942
G E+F++ + G L + +S +++ VDG VALP +
Sbjct: 2110 GAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSL 2169
Query: 943 VRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNG 1002
+ G ++V+ TT GL L FDGD+ + + +P+ + LCGLCGN+N + +DD G
Sbjct: 2170 LHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGG 2229
Query: 1003 SAASSVETFGAAWRVPGSSKGCGEGCGPQGCP-VCLAEETAPYESNEACGQLRNPQGPFA 1061
A W+V G ++GCGE C + CP C E+ + +ACG + GP A
Sbjct: 2230 KP--------AGWQV-GGAQGCGE-CVSKPCPSPCTPEQQESFGGPDACGVISATDGPLA 2279
Query: 1062 TCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHC 1121
C ++ P++YF+ C+ D C +G LC ++A Y AACQAAG + WR FCPL C
Sbjct: 2280 PCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQC 2339
Query: 1122 PAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQDCGCTHNGR 1181
PAHSHY +C +C SC +LS GC + C EGC CD F+LS C+PV CGC H+GR
Sbjct: 2340 PAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGR 2399
Query: 1182 YLPVNSSLLTS-DCSERCSCSSSSGLTCQ-AAGCPPGRVCEVKAEARNCWATR-GLCVLS 1238
Y P+ +C RC C +TCQ A C P C ++ + C AT G C+ +
Sbjct: 2400 YYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLAN 2459
Query: 1239 VGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGK----------- 1287
G + T DG VY+L C Q+CH K
Sbjct: 2460 GGIHYITLDGR--------VYDLHGSCS-----------YVLAQVCHPKPGDEDFSIVLE 2500
Query: 1288 TEAVGQVH---IFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKA 1344
A G + + +V+L + V V+G V LP +A V T +G +V Q
Sbjct: 2501 KNAAGDLQRLLVTVAGQVVSLAQGQQVTVDGEAVALP---VAVGRVRVTAEGRNMVLQTT 2557
Query: 1345 -GVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTNDW 1383
G+++ + + + + + G+LCG CGNF+G+ ++D+
Sbjct: 2558 KGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDF 2597
>gi|154146262 Fc fragment of IgG binding protein [Homo sapiens]
Length = 5405
Score = 2930 bits (7595), Expect = 0.0
Identities = 1355/1370 (98%), Positives = 1360/1370 (99%)
Query: 33 QPLKVLLPLLSPDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFD 92
QP +L ++ DPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFD
Sbjct: 4033 QPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFD 4092
Query: 93 FQGTCNYVLATTGCLGVSTQGLTPFTVTTKNENRGNPAVSYVRVVTVAALGTNISIHKDE 152
FQGTCNYVLATTGC GVSTQGLTPFTVTTKN+NRGNPAVSYVRVVTVAALGTNISIHKDE
Sbjct: 4093 FQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDE 4152
Query: 153 IGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGA 212
IGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGA
Sbjct: 4153 IGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGA 4212
Query: 213 VCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLE 272
VCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLE
Sbjct: 4213 VCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLE 4272
Query: 273 QYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAAC 332
QYEGPGFCGPL+ GTGGPFTTCHAHVPPESFFKGCVLDVCMGGGD DILCKALASYVAAC
Sbjct: 4273 QYEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAAC 4332
Query: 333 QAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCD 392
QAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCD
Sbjct: 4333 QAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCD 4392
Query: 393 AGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGL 452
AGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGL
Sbjct: 4393 AGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGL 4452
Query: 453 GEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAE 512
GEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAE
Sbjct: 4453 GEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAE 4512
Query: 513 NFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHA 572
NFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHA
Sbjct: 4513 NFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHA 4572
Query: 573 HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA 632
HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA
Sbjct: 4573 HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA 4632
Query: 633 GWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQ 692
GWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQ
Sbjct: 4633 GWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQ 4692
Query: 693 GCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSC 752
GCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSC
Sbjct: 4693 GCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSC 4752
Query: 753 PVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPE 812
PVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPE
Sbjct: 4753 PVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPE 4812
Query: 813 CERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVY 872
CERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVY
Sbjct: 4813 CERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVY 4872
Query: 873 DLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVSLAQGQQVTVDGE 932
DLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVSLAQGQQVTVDGE
Sbjct: 4873 DLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVSLAQGQQVTVDGE 4932
Query: 933 AVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGN 992
AVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGN
Sbjct: 4933 AVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGN 4992
Query: 993 WSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQ 1052
WSDDFVLPNGSAASSVETFGAAWR PGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQ
Sbjct: 4993 WSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQ 5052
Query: 1053 LRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWR 1112
LRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWR
Sbjct: 5053 LRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWR 5112
Query: 1113 TDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQ 1172
TDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQ
Sbjct: 5113 TDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQ 5172
Query: 1173 DCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATR 1232
DCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATR
Sbjct: 5173 DCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATR 5232
Query: 1233 GLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVG 1292
GLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVG
Sbjct: 5233 GLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVG 5292
Query: 1293 QVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQVWLGA 1352
QVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQVWLGA
Sbjct: 5293 QVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQVWLGA 5352
Query: 1353 NGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHDSQEKPAMEKWRAQDFSP 1402
NGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHDSQEKPAMEKWRAQDFSP
Sbjct: 5353 NGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHDSQEKPAMEKWRAQDFSP 5402
Score = 2019 bits (5231), Expect = 0.0
Identities = 977/1428 (68%), Positives = 1092/1428 (76%), Gaps = 64/1428 (4%)
Query: 33 QPLKVLLPLLSPDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFD 92
QP +L ++ DPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFD
Sbjct: 2832 QPSGGILSCVNKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFD 2891
Query: 93 FQGTCNYVLATTGCLGVSTQGLTPFTVTTKNENRGNPAVSYVRVVTVAALGTNISIHKDE 152
FQGTCNYVLATTGC GVSTQGLTPFTVTTKN+NRGNPAVSYVRVVTVAALGTNISIHKDE
Sbjct: 2892 FQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDE 2951
Query: 153 IGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGA 212
IGKVRVNGVLTALPVSVADGRISV QGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGA
Sbjct: 2952 IGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGA 3011
Query: 213 VCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLE 272
VCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLE
Sbjct: 3012 VCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLE 3071
Query: 273 QYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAAC 332
QYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGD DILCKALASYVAAC
Sbjct: 3072 QYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAAC 3131
Query: 333 QAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCD 392
QAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCD
Sbjct: 3132 QAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCD 3191
Query: 393 AGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGL 452
AGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGL
Sbjct: 3192 AGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGL 3251
Query: 453 GEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAE 512
GEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAE
Sbjct: 3252 GEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAE 3311
Query: 513 NFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHA 572
NFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFV LPFQLDSLLHA
Sbjct: 3312 NFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHA 3371
Query: 573 HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA 632
HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYA SLCGLCGNYNQDPADDLKAVGGKPA
Sbjct: 3372 HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPA 3431
Query: 633 GWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQ 692
GWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQ
Sbjct: 3432 GWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQ 3491
Query: 693 GCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSC 752
GCLLDACQVQGHPGGLCPAVATYVAACQAAGAQL EWRRPDFCP QCPAHSHYELCGDSC
Sbjct: 3492 GCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSC 3551
Query: 753 PVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPE 812
P SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHD RYYPLG+ FYPGP
Sbjct: 3552 PGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPG 3611
Query: 813 CERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVY 872
C+ C C GG V+C E ++CGPHE CR G C A G C A+G HY T DG +
Sbjct: 3612 CDSLCRCREGGEVSC-EPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGHRF 3670
Query: 873 DLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGD-----LQRLLVTVAGQVVSLAQGQ-Q 926
D G+C YVLAQ C +PG F+++ E A G+ + + V VA + L Q Q +
Sbjct: 3671 DFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWK 3730
Query: 927 VTVDGEAVALPV--AVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCG 984
VTV+G + LPV A G++R + G ++V++T GLR+ +D ++ +++P + +CG
Sbjct: 3731 VTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCG 3790
Query: 985 LCGNFNGNWSDDFVLPNGSAASSVETFGAAWR--VPGSSKGCGEGCGPQGCPVCLAEETA 1042
LCGN+NG+ DDF PNGS A + FG +W VP S C P G C+ +
Sbjct: 3791 LCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTC-PPGSAGCIPSDKC 3849
Query: 1043 P------YESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAA 1096
P Y+ E CG L +P GP ++C ++ P + C++DLC G+ + LC ++ A
Sbjct: 3850 PPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHA 3909
Query: 1097 YTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCE 1156
Y +ACQAAG V+PWR ++FCP+ CP +SHY +C TC C+ALS C C EGC+
Sbjct: 3910 YVSACQAAGGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQ 3969
Query: 1157 CDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPG 1216
CD FL + C+P+Q CGC HNG Y ++L +C ++C+C + CQ C PG
Sbjct: 3970 CDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPG 4029
Query: 1217 RVCEVKAEARNC-------------------WATRGLCVLSVGA--------NLTTFDGA 1249
+VC+ +C +G+C+ + A + +FDG
Sbjct: 4030 QVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGR 4089
Query: 1250 RGATTSPGVYELSSR-CPGL--QNTIPWYRVVAEVQICHGKTEAVGQVHIFFQDGMVT-L 1305
+ Y L++ CPG+ Q P + V + Q + AV V + + T +
Sbjct: 4090 KFDFQGTCNYVLATTGCPGVSTQGLTP-FTVTTKNQ--NRGNPAVSYVRVVTVAALGTNI 4146
Query: 1306 TPNKG----VWVNGLRVDLPAEKL-ASVSVSRTPDGSLLVRQKAGVQVWLGANGKVAVIV 1360
+ +K V VNG+ LP +SV++ +LLV G+QV N +V V +
Sbjct: 4147 SIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVAD-FGLQVSYDWNWRVDVTL 4205
Query: 1361 SNDHAGKLCGACGNFDGDQTND--WHDSQEKPAME----KWRAQDFSP 1402
+ + G +CG CGN D + ND + + P++ WRA + P
Sbjct: 4206 PSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDP 4253
Score = 2018 bits (5229), Expect = 0.0
Identities = 976/1428 (68%), Positives = 1092/1428 (76%), Gaps = 64/1428 (4%)
Query: 33 QPLKVLLPLLSPDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFD 92
QP +L ++ DPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFD
Sbjct: 1631 QPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFD 1690
Query: 93 FQGTCNYVLATTGCLGVSTQGLTPFTVTTKNENRGNPAVSYVRVVTVAALGTNISIHKDE 152
FQGTCNYVLATTGC GVSTQGLTPFTVTTKN+NRGNPAVSYVRVVTVAALGTNISIHKDE
Sbjct: 1691 FQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDE 1750
Query: 153 IGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGA 212
IGKVRVNGVLTALPVSVADGRISV QGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGA
Sbjct: 1751 IGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGA 1810
Query: 213 VCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLE 272
VCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLE
Sbjct: 1811 VCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLE 1870
Query: 273 QYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAAC 332
QYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGD DILCKALASYVAAC
Sbjct: 1871 QYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAAC 1930
Query: 333 QAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCD 392
QAAGVVIEDWRAQVGCEITCPENSHYEVCG PCPASCPSPAPLTTPAVCEGPCVEGCQCD
Sbjct: 1931 QAAGVVIEDWRAQVGCEITCPENSHYEVCGSPCPASCPSPAPLTTPAVCEGPCVEGCQCD 1990
Query: 393 AGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGL 452
AGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGL
Sbjct: 1991 AGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGL 2050
Query: 453 GEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAE 512
GEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRF+FQGTCEYLLSAPCHGPPLGAE
Sbjct: 2051 GEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAE 2110
Query: 513 NFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHA 572
NFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFV LPFQLDSLLHA
Sbjct: 2111 NFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHA 2170
Query: 573 HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA 632
HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYA SLCGLCGNYNQDPADDLKAVGGKPA
Sbjct: 2171 HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPA 2230
Query: 633 GWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQ 692
GWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQ
Sbjct: 2231 GWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQ 2290
Query: 693 GCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSC 752
GCLLDACQVQGHPGGLCPAVATYVAACQAAGAQL EWRRPDFCP QCPAHSHYELCGDSC
Sbjct: 2291 GCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSC 2350
Query: 753 PVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPE 812
P SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHD RYYPLG+ FYPGP
Sbjct: 2351 PGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPG 2410
Query: 813 CERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVY 872
C+ C C GG V+C E ++CGPHE CR G C A G C A+G HY T DGR +
Sbjct: 2411 CDSLCRCREGGEVSC-EPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGRRF 2469
Query: 873 DLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGD-----LQRLLVTVAGQVVSLAQGQ-Q 926
D G+C YVLAQ C +PG F+++ E A G+ + + V VA + L Q Q +
Sbjct: 2470 DFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWK 2529
Query: 927 VTVDGEAVALPVAV--GRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCG 984
VTV+G + LPV + G++R + G ++V++T GLR+ +D ++ +++P + +CG
Sbjct: 2530 VTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCG 2589
Query: 985 LCGNFNGNWSDDFVLPNGSAASSVETFGAAWR--VPGSSKGCGEGCGPQGCPVCLAEETA 1042
LCGN+NG+ DDF PNGS A + FG +W VP S C P G C+ E
Sbjct: 2590 LCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTC-PPGSEGCIPSEEC 2648
Query: 1043 P------YESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAA 1096
P Y+ E CG L +P GP ++C ++ P + C++DLC G+ + LC ++ A
Sbjct: 2649 PPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHA 2708
Query: 1097 YTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCE 1156
Y +ACQAAG V+PWR ++FCP+ CP +SHY +C TC C+ALS C C EGC+
Sbjct: 2709 YVSACQAAGGQVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQ 2768
Query: 1157 CDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPG 1216
CD FL + C+P+Q CGC HNG Y ++L +C ++C+C + CQ C PG
Sbjct: 2769 CDSGFLYNGQACVPIQQCGCYHNGAYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPG 2828
Query: 1217 RVCEVKAEARNC-------------------WATRGLCVLSVGA--------NLTTFDGA 1249
+VC+ +C +G+C+ + A + +FDG
Sbjct: 2829 QVCQPSGGILSCVNKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGR 2888
Query: 1250 RGATTSPGVYELSSR-CPGL--QNTIPWYRVVAEVQICHGKTEAVGQVHIFFQDGMVT-L 1305
+ Y L++ CPG+ Q P + V + Q + AV V + + T +
Sbjct: 2889 KFDFQGTCNYVLATTGCPGVSTQGLTP-FTVTTKNQ--NRGNPAVSYVRVVTVAALGTNI 2945
Query: 1306 TPNKG----VWVNGLRVDLPAEKL-ASVSVSRTPDGSLLVRQKAGVQVWLGANGKVAVIV 1360
+ +K V VNG+ LP +SV++ +LLV G+QV N +V V +
Sbjct: 2946 SIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVAD-FGLQVSYDWNWRVDVTL 3004
Query: 1361 SNDHAGKLCGACGNFDGDQTND--WHDSQEKPAME----KWRAQDFSP 1402
+ + G +CG CGN D + ND + + P++ WRA + P
Sbjct: 3005 PSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDP 3052
Score = 1025 bits (2649), Expect = 0.0
Identities = 553/1433 (38%), Positives = 776/1433 (54%), Gaps = 88/1433 (6%)
Query: 41 LLSP--DPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCN 98
+LSP C G+ C + C+ GG+ C+ A C GDPHY +FDGR++D GTC+
Sbjct: 436 VLSPVEPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCS 495
Query: 99 YVLATTGCLGVSTQGLTPFTVTTKNENRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRV 158
Y + L L F+V KNE+RG+ VSYV +VTV A ++S+ + E+G V V
Sbjct: 496 YTMVE---LCSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLV 552
Query: 159 NGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCG 218
+ + LPVS+++GR+ V Q +A++ FGL V+YDW+ ++ ++LP+ + VCGLCG
Sbjct: 553 DNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCG 612
Query: 219 NMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPG 278
N + +P +D + P+G LAP + SW+ D LC D C+ +CP C + + YEG
Sbjct: 613 NYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDR 672
Query: 279 FCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVV 338
CG L GPF CH + P F + CV D+C+ GG+ LC+ L++Y AC G+
Sbjct: 673 LCGMLTK-LDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGIS 731
Query: 339 IEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEG-PCVEGCQCDAGFVL 397
+ DWR+ C ++CP NS YE+CGP CP SC A P+ C G PCVEGC C GFV
Sbjct: 732 VGDWRSPANCPLSCPANSRYELCGPACPTSCNGAA---APSNCSGRPCVEGCVCLPGFVA 788
Query: 398 SADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPA-SCGLGEVC 456
S CVP ++ CGC G G E WAD C + C C + C SC GE C
Sbjct: 789 SGGACVPASS-CGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERC 847
Query: 457 GLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTV 516
+ +G GC P CQ GDPHYV+ DG RFDF GTC YLL C G F V
Sbjct: 848 SV-QNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSC-GQNAALPAFRV 905
Query: 517 TVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQL-DSLLHAHLS 575
V NEHRGSQ VSYTR+V ++ + + +P ++ VD V LPFQ D +
Sbjct: 906 LVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQ 965
Query: 576 GADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAG-- 633
G D VV T GL++ +D ++ V +VP++YA +LCGLCGN+N DPADDL GG A
Sbjct: 966 GRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANA 1025
Query: 634 ------WQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPP 687
WQ GCG CP + Q+ + CG+++ GP CH + P
Sbjct: 1026 LAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQ-LQSKNECGILADPKGPFRECHSKLDP 1084
Query: 688 AQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYEL 747
+ C+ D C + G G LC A+ATY AACQAAGA + WR + CPL CP HSHYE
Sbjct: 1085 QGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEA 1144
Query: 748 CGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVF 807
C CP+SC L P GC S C EGCVCD GF LSG++C+P+ CGC+H G Y+P G+ F
Sbjct: 1145 CSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTF 1204
Query: 808 YPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITL 867
YPGP C+ C C GG V+C E ++CGPHE C+ G C A G C A+G HY T
Sbjct: 1205 YPGPGCDSLCHCQEGGLVSC-ESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTF 1263
Query: 868 DGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGD-----LQRLLVTVAGQVVSLA 922
DGR +D G+C YVLAQ C +PG F+++ E A G+ + + V VA + L
Sbjct: 1264 DGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLE 1323
Query: 923 QGQ-QVTVDGEAVALPVAV--GRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFR 979
Q Q +VTV+G + LPV + G++R + G ++V++T GLR+ +D ++ +++P +
Sbjct: 1324 QRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYY 1383
Query: 980 GRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWR--VPGSSKGCGEGCGPQGCPVCL 1037
++CGLCGN+NG+ DDF PNGS A + FG +W VP S C P G C+
Sbjct: 1384 QQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPC-PPGSEDCI 1442
Query: 1038 AEETAP------YESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLC 1091
P Y+ E CG L +P GP ++C ++ P + C++DLC G+ + LC
Sbjct: 1443 PSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILC 1502
Query: 1092 RSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRC 1151
++ AY +ACQAAG V+PWRT++FCP+ CP +SHY +C TC C+ALS C C
Sbjct: 1503 SNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGC 1562
Query: 1152 FEGCECDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAA 1211
EGC+CD FL + C+P+Q CGC HNG Y ++L +C ++C+C + G+ CQ
Sbjct: 1563 AEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEH 1622
Query: 1212 GCPPGRVCEVKAEARNCWAT-------------------RGLCVLSVGA--------NLT 1244
C PG+VC+ +C +G+C+ + A +
Sbjct: 1623 SCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYH 1682
Query: 1245 TFDGARGATTSPGVYELSSR-CPGL--QNTIPWYRVVAEVQICHGKTEAVGQVHIFFQDG 1301
+FDG + Y L++ CPG+ Q P + V + Q + AV V +
Sbjct: 1683 SFDGRKFDFQGTCNYVLATTGCPGVSTQGLTP-FTVTTKNQ--NRGNPAVSYVRVVTVAA 1739
Query: 1302 MVT-LTPNKG----VWVNGLRVDLPAEKL-ASVSVSRTPDGSLLVRQKAGVQVWLGANGK 1355
+ T ++ +K V VNG+ LP +SV++ +LLV G+QV N +
Sbjct: 1740 LGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVAD-FGLQVSYDWNWR 1798
Query: 1356 VAVIVSNDHAGKLCGACGNFDGDQTND--WHDSQEKPAME----KWRAQDFSP 1402
V V + + + G +CG CGN D + ND + + P++ WRA + P
Sbjct: 1799 VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDP 1851
Score = 904 bits (2336), Expect = 0.0
Identities = 520/1407 (36%), Positives = 725/1407 (51%), Gaps = 98/1407 (6%)
Query: 47 CHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGC 106
C +C P ETC+ GG C+ TC GDPHY +FDGR+FDF GTC YVLA T C
Sbjct: 2425 CEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGRRFDFMGTCVYVLAQT-C 2483
Query: 107 LGVSTQGLTPFTVTTKNENRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALP 166
+ GL F V +N GN VS RV+TV + + + + KV VNGV LP
Sbjct: 2484 --GTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQ-WKVTVNGVDMKLP 2540
Query: 167 VSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNN 226
V +A+G+I +Q S ++ DFGL+V+YD + V VT+P +Y+ +CGLCGN + +P +
Sbjct: 2541 VVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGNYNGDPKD 2600
Query: 227 DQVFPNGTLAPSIPIWGGSWRAPGWD------PLCWDECRGSCPT--CPEDRLEQYEGPG 278
D PNG+ A + +G SW D P C G P+ CP + ++Y+
Sbjct: 2601 DFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSEGCIPSEECPPELEKKYQKEE 2660
Query: 279 FCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVV 338
FCG L+ TG P ++CH V P+ K C+ D+C+GGG+ ILC + +YV+ACQAAG
Sbjct: 2661 FCGLLSSPTG-PLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGQ 2719
Query: 339 IEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLS 398
+E WR + C + CP+NSHYE+C C C + L+ P C C EGCQCD+GF+ +
Sbjct: 2720 VEPWRNETFCPMECPQNSHYELCADTCSLGCSA---LSAPLQCPDGCAEGCQCDSGFLYN 2776
Query: 399 ADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVC-- 456
CVP+ CGC+ NG Y+E D C Q C C G +VC SC G+VC
Sbjct: 2777 GQACVPIQQ-CGCYHNGAYYEPEQTVLIDN-CRQQCTCHVGK-VVVCQEHSCKPGQVCQP 2833
Query: 457 --GLLP---------------------SGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQ 493
G+L GQ C P A C WGDPHY + DG +FDFQ
Sbjct: 2834 SGGILSCVNKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQ 2893
Query: 494 GTCEYLLSAP-CHGPPL-GAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPR 551
GTC Y+L+ C G G FTVT N++RG+ AVSY R VT+ ++++
Sbjct: 2894 GTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIG 2953
Query: 552 KLQVDGVFVALPFQL-DSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLC 610
K++V+GV ALP + D + + ++ GL +++D + V + +P++Y ++C
Sbjct: 2954 KVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVC 3013
Query: 611 GLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQG-CGECVSKPCPSPCTPEQQES 661
GLCGN +++P +D G A W+ G C + CP+ C ++ E
Sbjct: 3014 GLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPT-CPEDRLEQ 3072
Query: 662 FGGPDACGVIS-ATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQ 720
+ GP CG ++ T GP CH VPP +F+GC+LD C G LC A+A+YVAACQ
Sbjct: 3073 YEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQ 3132
Query: 721 AAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPS---LSAPEGCESACREGCVCDA 777
AAG + +WR C + CP +SHYE+CG CP SCPS L+ P CE C EGC CDA
Sbjct: 3133 AAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDA 3192
Query: 778 GFVLSGDTCVPVGQ-CGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPH 836
GFVLS D CVP+ CGC +G Y+ G F+ C + C CGPGG A+CG
Sbjct: 3193 GFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLG 3252
Query: 837 EECRL-EDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKP-GDED 894
E C L G C C A G HY+TLDG +D G+C Y+L+ CH P G E+
Sbjct: 3253 EVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAEN 3312
Query: 895 FSIVLEKNAAGDLQ-------RLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRV-RVT 946
F++ + G L + +S +++ VDG V LP + +
Sbjct: 3313 FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAH 3372
Query: 947 AEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAAS 1006
G ++V+ TT GL L FDGD+ + + +P+ + G LCGLCGN+N + +DD G A
Sbjct: 3373 LSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPAG 3432
Query: 1007 SVETFGAAWRVPGSSKGCGEGCGPQGCPV-CLAEETAPYESNEACGQLRNPQGPFATCQA 1065
W+V G ++GCGE C + CP C E+ + +ACG + GP A C
Sbjct: 3433 --------WQV-GGAQGCGE-CVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHG 3482
Query: 1066 VLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHS 1125
++ P++YF+ C+ D C +G LC ++A Y AACQAAG ++ WR FCP CPAHS
Sbjct: 3483 LVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHS 3542
Query: 1126 HYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQDCGCTHNGRYLPV 1185
HY +C +C GSC +LS GC + C EGC CD F+LS C+PV CGC H+ RY P+
Sbjct: 3543 HYELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPL 3602
Query: 1186 NSSLLTSD-CSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATRGL-CVLSVGANL 1243
+ C C C ++C+ + C P C + C A C S +
Sbjct: 3603 GQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHY 3662
Query: 1244 TTFDGARGATTSPGVYELSSRC---PGLQNTIPWYRVVAEVQICHGKTEAVGQVHIFFQD 1300
TTFDG R VY L+ C PGL V + + G I Q
Sbjct: 3663 TTFDGHRFDFMGTCVYVLAQTCGTRPGLHRF-----AVLQENVAWGNGRVSVTRVITVQV 3717
Query: 1301 GMVTLTPNKGVW---VNGLRVDLPAEKLASVSVSRTPDGS-LLVRQKAGVQVWLGANGKV 1356
TL + W VNG+ + LP LA+ + + GS +++ G++V V
Sbjct: 3718 ANFTLRLEQRQWKVTVNGVDMKLPVV-LANGQIRASQHGSDVVIETDFGLRVAYDLVYYV 3776
Query: 1357 AVIVSNDHAGKLCGACGNFDGDQTNDW 1383
V V ++ +CG CGN++GD +D+
Sbjct: 3777 RVTVPGNYYQLMCGLCGNYNGDPKDDF 3803
Score = 889 bits (2296), Expect = 0.0
Identities = 530/1425 (37%), Positives = 729/1425 (51%), Gaps = 106/1425 (7%)
Query: 48 HGVTCRPQ------ETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVL 101
H VTCR + E C Q G C P+ TC GDPHY SFDGR+FDF GTC Y+L
Sbjct: 831 HQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLL 890
Query: 102 ATTGCLGVSTQGLTPFTVTTKNENRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGV 161
G G + L F V +NE+RG+ VSY R V V A G +++ ++ G+V V+ V
Sbjct: 891 V--GSCGQNA-ALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDV 947
Query: 162 LTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMD 221
L LP ADG++ V + A++ DFGL V+YDWN RV +PSSY A+CGLCGN +
Sbjct: 948 LQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFN 1007
Query: 222 RNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCG 281
+P +D G A + +G SW+ P C G CP +Q + CG
Sbjct: 1008 GDPADDLALRGGGQAANALAFGNSWQEET-RPGCGATEPGDCPKLDSLVAQQLQSKNECG 1066
Query: 282 PLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVVIED 341
LA G PF CH+ + P+ + CV D C+ G LC ALA+Y AACQAAG +
Sbjct: 1067 ILADPKG-PFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHP 1125
Query: 342 WRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADR 401
WR++ C ++CP +SHYE C CP SC L P C C EGC CD GF LS +
Sbjct: 1126 WRSEELCPLSCPPHSHYEACSYGCPLSC---GDLPVPGGCGSECHEGCVCDEGFALSGES 1182
Query: 402 CVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPS 461
C+PL + CGC GTYH G F+ C C C GG + C +SCG E C PS
Sbjct: 1183 CLPLAS-CGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGG-LVSCESSSCGPHEACQ--PS 1238
Query: 462 GQH-GCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVAN 520
G GC V ++ CQA GDPHY T DG RFDF GTC Y+L+ C P G F V N
Sbjct: 1239 GGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRP-GLHRFAVLQEN 1297
Query: 521 EHRGSQAVSYTRSVTLQIYNHSLTLSAR-WPRKLQVDGVFVALPFQL-DSLLHAHLSGAD 578
G+ VS TR +T+Q+ N +L L R W K+ V+GV + LP L + + A G+D
Sbjct: 1298 VAWGNGRVSVTRVITVQVANFTLRLEQRQW--KVTVNGVDMKLPVVLANGQIRASQHGSD 1355
Query: 579 VVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGG 638
VV+ T GL +A+D +VR+ VP Y +CGLCGNYN DP DD + KP G Q G
Sbjct: 1356 VVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQ----KPNGSQAGN 1411
Query: 639 AQGCGECVSK-----------PCPS---------PCTPEQQESFGGPDACGVISATDGPL 678
A G + PCP C PE ++ + + CG++S+ GPL
Sbjct: 1412 ANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPL 1471
Query: 679 APCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQ 738
+ CH LV P + C+ D C G+ LC + YV+ACQAAG + WR FCP++
Sbjct: 1472 SSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPME 1531
Query: 739 CPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDG 798
CP +SHYELC D+C + C +LSAP C+ C EGC CD+GF+ +G CVP+ QCGC H+G
Sbjct: 1532 CPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNG 1591
Query: 799 RYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQAC------HATG 852
YY + C ++C C G + CQE + C P + C+ G+ +C H
Sbjct: 1592 VYYEPEQTVLID-NCRQQCTCHAGKGMVCQEHS-CKPGQVCQPSGGILSCVTKDPCHGVT 1649
Query: 853 C------------GRCLAN--------GGIHYITLDGRVYDLHGSCSYVLAQVCHP---K 889
C G CL N G HY + DGR +D G+C+YVLA P
Sbjct: 1650 CRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVST 1709
Query: 890 PGDEDFSIVLEKNAAGD-----LQRLLVTVAGQVVSLAQGQ--QVTVDGEAVALPVAV-- 940
G F++ + G+ ++ + V G +S+ + + +V V+G ALPV+V
Sbjct: 1710 QGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVAD 1769
Query: 941 GRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLP 1000
GR+ VT +L GL++ +D + + +++PS + G +CGLCGN + N ++D V P
Sbjct: 1770 GRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFP 1829
Query: 1001 NGSAASSVETFGAAWRVPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLR-NPQGP 1059
NG+ A S+ +G +WR PG C + C CP C + YE CG L GP
Sbjct: 1830 NGTLAPSIPIWGGSWRAPGWDPLCWDECRGS-CPTCPEDRLEQYEGPGFCGPLAPGTGGP 1888
Query: 1060 FATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPL 1119
F TC A + P +F+ CV D+C GD+ LC++LA+Y AACQAAGV ++ WR C +
Sbjct: 1889 FTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEI 1948
Query: 1120 HCPAHSHYSICTRTCQGSCAALSGLTG---CTTRCFEGCECDDRFLLSQGVCIPVQD-CG 1175
CP +SHY +C C SC + + LT C C EGC+CD F+LS C+P+ + CG
Sbjct: 1949 TCPENSHYEVCGSPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCG 2008
Query: 1176 CTHNGRYLPVNSSLLTSD-CSERCSCSSSSG-LTCQAAGCPPGRVCEVKAEARN-CW-AT 1231
C NG Y S CS+ C C G L C A C G VC + ++ C +
Sbjct: 2009 CWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVS 2068
Query: 1232 RGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAV 1291
C + T DG R Y LS+ C G + V + H ++AV
Sbjct: 2069 TAECQAWGDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANE--HRGSQAV 2126
Query: 1292 G---QVHIFFQDGMVTLTPN--KGVWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGV 1346
V + + +TL+ + + V+G+ V LP + L S+ + ++V +G+
Sbjct: 2127 SYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQ-LDSLLHAHLSGADVVVTTTSGL 2185
Query: 1347 QVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHDSQEKPA 1391
+ + V + V +AG LCG CGN++ D +D KPA
Sbjct: 2186 SLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPA 2230
Score = 869 bits (2246), Expect = 0.0
Identities = 523/1422 (36%), Positives = 729/1422 (51%), Gaps = 110/1422 (7%)
Query: 47 CHGVTCRPQETCKE-QGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTG 105
C +C E C GQ C P A C WGDPHY + DG +F+FQGTC Y+L+
Sbjct: 2043 CTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFNFQGTCEYLLSAP- 2101
Query: 106 CLGVSTQGLTPFTVTTKNENRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTAL 165
C G G FTVT NE+RG+ AVSY R VT+ ++++ K++V+GV L
Sbjct: 2102 CHGPPL-GAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTL 2160
Query: 166 PVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPN 225
P + D + + ++ GL +++D + V + +P++Y G++CGLCGN +++P
Sbjct: 2161 PFQL-DSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPA 2219
Query: 226 NDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPT-CPEDRLEQYEGPGFCGPLA 284
+D G A W+ G C + CP+ C ++ E + GP CG ++
Sbjct: 2220 DDLKAVGGKPA--------GWQVGGAQG-CGECVSKPCPSPCTPEQQESFGGPDACGVIS 2270
Query: 285 PGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVVIEDWRA 344
T GP CH VPP +F+GC+LD C G LC A+A+YVAACQAAG + +WR
Sbjct: 2271 -ATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRR 2329
Query: 345 QVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVP 404
C CP +SHYE+CG CP SCPS L+ P CE C EGC CDAGFVLS D CVP
Sbjct: 2330 PDFCPFQCPAHSHYELCGDSCPGSCPS---LSAPEGCESACREGCVCDAGFVLSGDTCVP 2386
Query: 405 LNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQH 464
+ CGC + Y+ G F+ C CRC GG + C P+SCG E C PSG
Sbjct: 2387 VGQ-CGCLHDDRYYPLGQTFYPGPGCDSLCRCREGG-EVSCEPSSCGPHETCR--PSGGS 2442
Query: 465 -GCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHR 523
GC V + CQA GDPHY T DG RFDF GTC Y+L+ C P G F V N
Sbjct: 2443 LGCVAVGSTTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRP-GLHRFAVLQENVAW 2501
Query: 524 GSQAVSYTRSVTLQIYNHSLTLSAR-WPRKLQVDGVFVALPFQL-DSLLHAHLSGADVVV 581
G+ VS TR +T+Q+ N +L L R W K+ V+GV + LP L + + A G+DVV+
Sbjct: 2502 GNGRVSVTRVITVQVANFTLRLEQRQW--KVTVNGVDMKLPVVLANGQIRASQHGSDVVI 2559
Query: 582 TTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQG 641
T GL +A+D +VR+ VP Y +CGLCGNYN DP DD + KP G Q G A
Sbjct: 2560 ETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQ----KPNGSQAGNANE 2615
Query: 642 CGE----------CVSKP-CP---------SPCTPEQQESFGGPDACGVISATDGPLAPC 681
G C+ P CP C PE ++ + + CG++S+ GPL+ C
Sbjct: 2616 FGNSWEEVVPDSPCLPPPTCPPGSEGCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSC 2675
Query: 682 HGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPA 741
H LV P + C+ D C G+ LC + YV+ACQAAG Q+ WR FCP++CP
Sbjct: 2676 HKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGQVEPWRNETFCPMECPQ 2735
Query: 742 HSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYY 801
+SHYELC D+C + C +LSAP C C EGC CD+GF+ +G CVP+ QCGC H+G YY
Sbjct: 2736 NSHYELCADTCSLGCSALSAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGAYY 2795
Query: 802 PLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQAC------HATGC-- 853
+ C ++C C G V CQE + C P + C+ G+ +C H C
Sbjct: 2796 EPEQTVLID-NCRQQCTCHVGKVVVCQEHS-CKPGQVCQPSGGILSCVNKDPCHGVTCRP 2853
Query: 854 ----------GRCLAN--------GGIHYITLDGRVYDLHGSCSYVLAQVCHP---KPGD 892
G CL N G HY + DGR +D G+C+YVLA P G
Sbjct: 2854 QETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGL 2913
Query: 893 EDFSIVLEKNAAGD-----LQRLLVTVAGQVVSLAQGQ--QVTVDGEAVALPVAV--GRV 943
F++ + G+ ++ + V G +S+ + + +V V+G ALPV+V GR+
Sbjct: 2914 TPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRI 2973
Query: 944 RVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGS 1003
VT +L GL++ +D + + +++PS + G +CGLCGN + N ++D V PNG+
Sbjct: 2974 SVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGT 3033
Query: 1004 AASSVETFGAAWRVPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLR-NPQGPFAT 1062
A S+ +G +WR PG C + C CP C + YE CG L GPF T
Sbjct: 3034 LAPSIPIWGGSWRAPGWDPLCWDECRGS-CPTCPEDRLEQYEGPGFCGPLAPGTGGPFTT 3092
Query: 1063 CQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCP 1122
C A + P +F+ CV D+C GD+ LC++LA+Y AACQAAGV ++ WR C + CP
Sbjct: 3093 CHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCP 3152
Query: 1123 AHSHYSICTRTCQGSCAALSGLTG---CTTRCFEGCECDDRFLLSQGVCIPVQD-CGCTH 1178
+SHY +C C SC + + LT C C EGC+CD F+LS C+P+ + CGC
Sbjct: 3153 ENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWA 3212
Query: 1179 NGRYLPVNSSLLTSD-CSERCSCSSSSG-LTCQAAGCPPGRVCEVKAEARN-CW-ATRGL 1234
NG Y S CS+ C C G L C A C G VC + ++ C +
Sbjct: 3213 NGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAE 3272
Query: 1235 CVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVG-- 1292
C + T DG R Y LS+ C G + V + H ++AV
Sbjct: 3273 CQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANE--HRGSQAVSYT 3330
Query: 1293 -QVHIFFQDGMVTLTPN--KGVWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQVW 1349
V + + +TL+ + + V+G+ V LP + L S+ + ++V +G+ +
Sbjct: 3331 RSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQ-LDSLLHAHLSGADVVVTTTSGLSLA 3389
Query: 1350 LGANGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHDSQEKPA 1391
+ V + V +AG LCG CGN++ D +D KPA
Sbjct: 3390 FDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPA 3431
>gi|239757286 PREDICTED: similar to Fc fragment of IgG binding protein
[Homo sapiens]
Length = 1472
Score = 753 bits (1945), Expect = 0.0
Identities = 390/922 (42%), Positives = 518/922 (56%), Gaps = 33/922 (3%)
Query: 41 LLSP--DPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCN 98
+LSP C G+ C + C+ GG+ C+ A C GDPHY +FDGR++D GTC+
Sbjct: 497 VLSPVEPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCS 556
Query: 99 YVLATTGCLGVSTQGLTPFTVTTKNENRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRV 158
Y + L L F+V KNE+RG+ VSYV +VTV A ++S+ + E+G V V
Sbjct: 557 YTMVE---LCSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLV 613
Query: 159 NGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCG 218
+ + LPVS+++GR+ V Q +A++ FGL V+YDW+ ++ ++LP+ + VCGLCG
Sbjct: 614 DNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCG 673
Query: 219 NMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPG 278
N + +P +D + P+G LAP + SW+ D LC D C+ +CP C + + YEG
Sbjct: 674 NYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDR 733
Query: 279 FCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVV 338
CG L GPF CH + P F + CV D+C+ GG+ LC+ L++Y AC G+
Sbjct: 734 LCGMLTK-LDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGIS 792
Query: 339 IEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEG-PCVEGCQCDAGFVL 397
+ DWR+ C ++CP NS YE+CGP CP SC A P+ C G PCVEGC C GFV
Sbjct: 793 VGDWRSPANCPLSCPANSRYELCGPACPTSCNGAA---APSNCSGRPCVEGCVCLPGFVA 849
Query: 398 SADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPA-SCGLGEVC 456
S CVP ++ CGC G G E WAD C + C C + C SC GE C
Sbjct: 850 SGGACVPASS-CGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERC 908
Query: 457 GLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTV 516
+ +G GC P CQ GDPHYV+ DG RFDF GTC YLL C G F V
Sbjct: 909 SV-QNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSC-GQNAALPAFRV 966
Query: 517 TVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQL-DSLLHAHLS 575
V NEHRGSQ VSYTR+V ++ + + +P ++ VD V LPFQ D +
Sbjct: 967 LVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQ 1026
Query: 576 GADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAG-- 633
G D VV T GL++ +D ++ V +VP++YA +LCGLCGN+N DPADDL GG A
Sbjct: 1027 GRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANA 1086
Query: 634 ------WQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPP 687
WQ GCG CP + Q+ + CG+++ GP CH + P
Sbjct: 1087 LAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQ-LQSKNECGILADPKGPFRECHSKLDP 1145
Query: 688 AQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYEL 747
+ C+ D C + G G LC A+ATY AACQAAGA + WR + CPL CP HSHYE
Sbjct: 1146 QGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEA 1205
Query: 748 CGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVF 807
C CP+SC L P GC S C EGCVCD GF LSG++C+P+ CGC+H G Y+P G+ F
Sbjct: 1206 CSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTF 1265
Query: 808 YPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITL 867
YPGP C+ C C GG V+C E ++CGPHE C+ G C A G C A+G HY T
Sbjct: 1266 YPGPGCDSLCHCQEGGLVSC-ESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTF 1324
Query: 868 DGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGD-----LQRLLVTVAGQVVSLA 922
DGR +D G+C YVLAQ C +PG F+++ E A G+ + + V VA + L
Sbjct: 1325 DGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLE 1384
Query: 923 QGQ-QVTV--DGEAVALPVAVG 941
Q Q +VTV DGE A + VG
Sbjct: 1385 QRQWKVTVRADGEQGARGLWVG 1406
Score = 585 bits (1507), Expect = e-166
Identities = 320/862 (37%), Positives = 433/862 (50%), Gaps = 37/862 (4%)
Query: 445 CTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPC 504
C C G+ C ++ G+ GC STA C+A GDPHY T DG R+D GTC Y + C
Sbjct: 505 CEGMQCAAGQRCQVV-GGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELC 563
Query: 505 HGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPF 564
F+V NEHRGS+ VSY VT++ Y+HS++L+ + VD LP
Sbjct: 564 SEDDT-LPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPV 622
Query: 565 QL-DSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADD 623
L + L + SG VV GL + +D D + L +PA + +CGLCGNYN DPADD
Sbjct: 623 SLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADD 682
Query: 624 LKAVGGKPA--------GWQVG-GAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISAT 674
G A W++ G C + CP+ CTP Q + + G CG+++
Sbjct: 683 FLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPA-CTPGQAQHYEGDRLCGMLTKL 741
Query: 675 DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDF 734
DGP A CH + P + + C+ D C V G LC ++ Y AC G +G+WR P
Sbjct: 742 DGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPAN 801
Query: 735 CPLQCPAHSHYELCGDSCPVSCPSLSAPEGCESA-CREGCVCDAGFVLSGDTCVPVGQCG 793
CPL CPA+S YELCG +CP SC +AP C C EGCVC GFV SG CVP CG
Sbjct: 802 CPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCG 861
Query: 794 CLHDGRYYPLGEVFYPGPECERRCECGPGGH-VTCQEGAACGPHEECRLEDGVQACHATG 852
C G G+ + C+RRC C H VTC++ +C E C +++G+ C+
Sbjct: 862 CTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDR 921
Query: 853 CGRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGD-----L 907
G C +G HY++ DGR +D G+C+Y+L C F +++E G
Sbjct: 922 FGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYT 981
Query: 908 QRLLVTVAGQVVSLAQGQ--QVTVDGEAVALP--VAVGRVRVTAEGRNMVLQTTKGLRLL 963
+ + V G V++ + QV VD LP A G+V+V +GR+ V++T GL +
Sbjct: 982 RAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVT 1041
Query: 964 FDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKG 1023
+D +A + +PS + LCGLCGNFNG+ +DD L G A++ FG +W+ + G
Sbjct: 1042 YDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEE-TRPG 1100
Query: 1024 CGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQ 1083
CG P CP + +S CG L +P+GPF C + L P R CVYD C
Sbjct: 1101 CG-ATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLL 1159
Query: 1084 KGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSG 1143
G LC +LA Y AACQAAG V PWR++ CPL CP HSHY C+ C SC L
Sbjct: 1160 PGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPV 1219
Query: 1144 LTGCTTRCFEGCECDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTS-DCSERCSCSS 1202
GC + C EGC CD+ F LS C+P+ CGC H G Y P + C C C
Sbjct: 1220 PGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQE 1279
Query: 1203 SSGLTCQAAGCPPGRVCEVKAEARNCWAT-RGLCVLSVGANLTTFDGARGATTSPGVYEL 1261
++C+++ C P C+ + C A C S + TTFDG R VY L
Sbjct: 1280 GGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVL 1339
Query: 1262 SSRC---PG------LQNTIPW 1274
+ C PG LQ + W
Sbjct: 1340 AQTCGTRPGLHRFAVLQENVAW 1361
Score = 323 bits (827), Expect = 9e-88
Identities = 195/581 (33%), Positives = 282/581 (48%), Gaps = 39/581 (6%)
Query: 829 EGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHP 888
EG C + C++ G C A C A G HY T DGR YD+ G+CSY + ++C
Sbjct: 506 EGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSE 565
Query: 889 KPGDEDFSIVLEKNAAGDLQRL---LVTVAG--QVVSLAQGQQ--VTVDGEAVALPVAV- 940
FS+ + G + LVTV VSL +G+ V VD + LPV++
Sbjct: 566 DDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLS 625
Query: 941 -GRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVL 999
GR+RV G V++ GL + +D D L +S+P+ F+ ++CGLCGN+NG+ +DDF+
Sbjct: 626 EGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLT 685
Query: 1000 PNGSAASSVETFGAAWRVPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGP 1059
P+G+ A F ++W++ C +GC CP C + YE + CG L GP
Sbjct: 686 PDGALAPDAVEFASSWKLDDGDYLCEDGC-QNNCPACTPGQAQHYEGDRLCGMLTKLDGP 744
Query: 1060 FATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPL 1119
FA C L P + QCVYDLC G++ LCR L+AY AC G++V WR+ + CPL
Sbjct: 745 FAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPL 804
Query: 1120 HCPAHSHYSICTRTCQGSCAALSGLTGCTTR-CFEGCECDDRFLLSQGVCIPVQDCGCTH 1178
CPA+S Y +C C SC + + C+ R C EGC C F+ S G C+P CGCT
Sbjct: 805 SCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGCTF 864
Query: 1179 NGRYLPVNSSLLTSD-CSERCSCSSSSG-LTCQ-AAGCPPGRVCEVKAEARNCWATR-GL 1234
G L + + C RC+C+ ++ +TC+ CP G C V+ C+ R G
Sbjct: 865 QGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGT 924
Query: 1235 CVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVGQV 1294
C S + +FDG R Y L C G +P +RV+ E + H ++ V
Sbjct: 925 CQGSGDPHYVSFDGRRFDFMGTCTYLLVGSC-GQNAALPAFRVLVENE--HRGSQTVSYT 981
Query: 1295 HIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTP----DGSL---------LVR 1341
+ +GV V +R + P + L + P DG + +VR
Sbjct: 982 RAVRVEA-------RGVKV-AVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVR 1033
Query: 1342 QKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTND 1382
G+ V N +V V + +A LCG CGNF+GD +D
Sbjct: 1034 TDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADD 1074
Score = 42.7 bits (99), Expect = 0.002
Identities = 49/190 (25%), Positives = 82/190 (43%), Gaps = 23/190 (12%)
Query: 1207 TCQAAGCPPGRVCEVKAEARNCWA-TRGLCVLSVGANLTTFDGARGATTSPGVYELSSRC 1265
+C+ C G+ C+V C A + +C + TTFDG R Y + C
Sbjct: 504 SCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELC 563
Query: 1266 PGLQNTIPWYRVVAEVQICHGKTEA-VGQVHIFFQDGMVTLTPNKG--VWVNGLRVDLPA 1322
+T+P + V A+ + + + VG V + V+LT + V V+ R LP
Sbjct: 564 SE-DDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLP- 621
Query: 1323 EKLASVSVSRTPDGSLLVRQKA---------GVQVWLGANGKVAVIVSNDHAGKLCGACG 1373
VS+S +G L V Q G+ V + ++A+ + ++CG CG
Sbjct: 622 -----VSLS---EGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCG 673
Query: 1374 NFDGDQTNDW 1383
N++GD +D+
Sbjct: 674 NYNGDPADDF 683
>gi|134268640 tectorin alpha precursor [Homo sapiens]
Length = 2155
Score = 731 bits (1888), Expect = 0.0
Identities = 434/1374 (31%), Positives = 667/1374 (48%), Gaps = 53/1374 (3%)
Query: 47 CHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGC 106
C +C P E C+ +G C +TC ++G+PHYH+FDG F FQG+C Y+LA C
Sbjct: 294 CQEASCSPYEVCEPKGKFFYCSAVETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQ-C 352
Query: 107 LGVSTQGLTPFTVTTKNENRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALP 166
L T L F+V KNE+R AVS+V+ ++V G I I K G+V+VN ++T+LP
Sbjct: 353 L--QTSSLPFFSVEAKNEHRRGSAVSWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLP 410
Query: 167 VSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNN 226
V++ G + + Q + DFGL V++D +++P SY + CGLCGN ++NP +
Sbjct: 411 VTLDLGTVKIYQSGISTAVETDFGLLVTFDGQHYASISVPGSYINSTCGLCGNYNKNPLD 470
Query: 227 DQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPG 286
D + P+G A S+ G SWR D C C +C C Y G +CG L
Sbjct: 471 DFLRPDGRPAMSVLDLGESWRVYHADWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNK- 529
Query: 287 TGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVVIEDWRAQV 346
T GP C V P +F CV D+C + +LC+A+ +Y CQA G+ I DWR Q
Sbjct: 530 TDGPLWECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQT 589
Query: 347 GCEIT--CPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVP 404
GC T CP SHY VC CP +C + LT C PC EGC+C+ GFVLS +CVP
Sbjct: 590 GCVSTVQCPSFSHYSVCTSSCPDTC---SDLTASRNCATPCTEGCECNQGFVLSTSQCVP 646
Query: 405 LNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQH 464
L+ CGC +G Y+ G FWA C+ C C GG + C +CG GEVC + G
Sbjct: 647 LHK-CGCDFDGHYYTMGEFFWATANCTVQCLCEEGG-DVYCFNKTCGSGEVCAV-EDGYQ 703
Query: 465 GCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG 524
GC P C + T DG + F Y L C P E + + N+ +
Sbjct: 704 GCFPKRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERP---EYLEIDI-NKKKP 759
Query: 525 SQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDS-LLHAHLSGADVVVTT 583
++ R + + + + + + +++++G V LPF S L + + V +
Sbjct: 760 DAGPAWLRGLRILVADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVES 819
Query: 584 TSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA--------GWQ 635
+++ + + +R+ Y GLCG YN + +D+ GK W
Sbjct: 820 KGVVTVQYSDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWT 879
Query: 636 VGGAQGCGEC--VSKPCPSPCTPEQQESFGGPDACGVIS-ATDGPLAPCHGLVPPAQYFQ 692
GEC + K C + E + + CG+I+ ++ CHG+V Y++
Sbjct: 880 TFEEICNGECGDLLKACNNDS--ELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYYR 937
Query: 693 GCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSC 752
CL CQ G+ LC +VA Y +AC+ A ++G WR DFCPL+CP +SH+E C +C
Sbjct: 938 TCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEEC-ITC 996
Query: 753 PVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPE 812
+C +L+ C +C EGC CD G+ L G CV +CGC +G E F+ +
Sbjct: 997 TETCETLTLGPICVDSCSEGCQCDEGYALLGSQCVTRSECGCNFEGHQLATNETFWVDLD 1056
Query: 813 CERRCEC-GPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRV 871
C+ C C G V C E C E C E G+ C A C+ +G HY+T DG
Sbjct: 1057 CQIFCYCSGTDNRVHC-ETIPCKDDEYCMEEGGLYYCQARTDASCIVSGYGHYLTFDGFP 1115
Query: 872 YDLHGSCSYVLAQVCHPKPGDEDFS--IVLEKNAAGD------LQRLLVTVAGQ--VVSL 921
+D SC +L +P + F +V KN D ++++ VTV G V+
Sbjct: 1116 FDFQTSCPLILCTT-GSRPSSDSFPKFVVTAKNEDRDPSLALWVKQVDVTVFGYSIVIHR 1174
Query: 922 AQGQQVTVDGEAVALPVAVG--RVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFR 979
A V V+ E + LP+ +G ++ + + G ++V++T GL++++D L +++P +
Sbjct: 1175 AYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYDWKTFLSITVPRSMQ 1234
Query: 980 GRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEGCGPQGCPVCLAE 1039
GLCG +NGN DD +P G ASSV FG +W + C GCG + CP C
Sbjct: 1235 NSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKRDTF--CQVGCGDR-CPSCAKV 1291
Query: 1040 ETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTA 1099
E + + C + N F+ C + ++P+ +++ C++D C G C L Y +
Sbjct: 1292 EGFS-KVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGAVQTACSWLQNYAS 1350
Query: 1100 ACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDD 1159
CQ G+ V WR + C + CP +SHY C CQ CAA+ + C+ C EGC CD
Sbjct: 1351 TCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCAAIRLKSDCSHYCVEGCHCDA 1410
Query: 1160 RFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVC 1219
++L+ CI CGC +G+Y SDC+ RC C + + C C C
Sbjct: 1411 GYVLNGKSCILPHSCGCYSDGKYYEPKQLFWNSDCTRRCRCFRRNVIQCDPRQCKSDEEC 1470
Query: 1220 EVKAEARNCWATR-GLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYRVV 1278
++ R C++T+ C+ + G TFDGA + + LS+ C L + I + ++
Sbjct: 1471 ALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANCAFVLSTICQKLPD-ISFQLII 1529
Query: 1279 AEVQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDGSL 1338
+ + V+ + + + + V VNG +V++P + + + +G L
Sbjct: 1530 NFDKWSAPNLTIISPVYFYINEEQILINDRNTVKVNGTQVNVPFITGLATKI-YSSEGFL 1588
Query: 1339 LVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHDSQEKPAM 1392
++ +Q++ + + +S K+CG CGNF+GD T+D+ + KP +
Sbjct: 1589 VIDTSPDIQIYYNGFNVIKISISERLQNKVCGLCGNFNGDLTDDYVTLRGKPVV 1642
Score = 496 bits (1276), Expect = e-140
Identities = 294/865 (33%), Positives = 420/865 (48%), Gaps = 36/865 (4%)
Query: 410 GCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQ-HGCQP 468
GC + G + G FW D C+ CRC + C ASC EVC P G+ C
Sbjct: 259 GCTSRGQFLRRGEVFWDDLNCTVKCRCLDFNNEIYCQEASCSPYEVCE--PKGKFFYCSA 316
Query: 469 VSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAV 528
V T+ C +G+PHY T DG F FQG+C YLL+ C F+V NEHR AV
Sbjct: 317 VETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCL-QTSSLPFFSVEAKNEHRRGSAV 375
Query: 529 SYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLD-SLLHAHLSGADVVVTTTSGL 587
S+ + +++++ + + + +++V+ + +LP LD + + SG V T GL
Sbjct: 376 SWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQSGISTAVETDFGL 435
Query: 588 SLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGA 639
+ FDG + + VP +Y S CGLCGNYN++P DD G+PA W+V A
Sbjct: 436 LVTFDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHA 495
Query: 640 Q-GCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDA 698
C C + C + + G D CG ++ TDGPL C +V P + C+ D
Sbjct: 496 DWKCDSGCVDNC-TQCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDL 554
Query: 699 CQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFC--PLQCPAHSHYELCGDSCPVSC 756
C V+ + LC A+ Y CQA G +G+WR C +QCP+ SHY +C SCP +C
Sbjct: 555 CSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSSCPDTC 614
Query: 757 PSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERR 816
L+A C + C EGC C+ GFVLS CVP+ +CGC DG YY +GE F+ C +
Sbjct: 615 SDLTASRNCATPCTEGCECNQGFVLSTSQCVPLHKCGCDFDGHYYTMGEFFWATANCTVQ 674
Query: 817 CECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHG 876
C C GG V C CG E C +EDG Q C CL + T DG Y
Sbjct: 675 CLCEEGGDVYC-FNKTCGSGEVCAVEDGYQGCFPKRETVCLLSQNQVLHTFDGASYAFPS 733
Query: 877 SCSYVLAQVCHPKPGDEDFSIVLEKNAAGD--LQRLLVTVAGQVVSLA--QGQQVTVDGE 932
SY L + C +P + I +K AG L+ L + VA Q V + +V ++G+
Sbjct: 734 EFSYTLLKTCPERPEYLEIDINKKKPDAGPAWLRGLRILVADQEVKIGGIGASEVKLNGQ 793
Query: 933 AVALPV--AVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLL-MSIPSPFRGRLCGLCGNF 989
V LP G++ + +N +KG+ + D LL + + + + GLCG +
Sbjct: 794 EVELPFFHPSGKLEI-YRNKNSTTVESKGVVTVQYSDIGLLYIRLSTTYFNCTGGLCGFY 852
Query: 990 NGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEGCGP--QGCPVCLAEETAPYESN 1047
N N SD+F LPNG ++ F +W + C CG + C +E Y S
Sbjct: 853 NANASDEFCLPNGKCTDNLAVFLESWTT--FEEICNGECGDLLKACNND-SELLKFYRSR 909
Query: 1048 EACGQLRNP-QGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGV 1106
CG + +P F C V++ + Y+R C++ LC G+++ LC S+A Y +AC+ A V
Sbjct: 910 SRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRLCQSGGNESELCDSVARYASACKNADV 969
Query: 1107 AVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQG 1166
V PWRT FCPL CP +SH+ C TC +C L+ C C EGC+CD+ + L
Sbjct: 970 EVGPWRTYDFCPLECPENSHFEECI-TCTETCETLTLGPICVDSCSEGCQCDEGYALLGS 1028
Query: 1167 VCIPVQDCGCTHNGRYLPVNSSL-LTSDCSERCSCSSSSG-LTCQAAGCPPGRVCEVKAE 1224
C+ +CGC G L N + + DC C CS + + C+ C C +
Sbjct: 1029 QCVTRSECGCNFEGHQLATNETFWVDLDCQIFCYCSGTDNRVHCETIPCKDDEYCMEEGG 1088
Query: 1225 ARNCWA-TRGLCVLSVGANLTTFDG 1248
C A T C++S + TFDG
Sbjct: 1089 LYYCQARTDASCIVSGYGHYLTFDG 1113
Score = 487 bits (1253), Expect = e-137
Identities = 307/1097 (27%), Positives = 484/1097 (44%), Gaps = 50/1097 (4%)
Query: 47 CHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGC 106
C TC E C + G C P E C L + H+FDG + F +Y L T
Sbjct: 685 CFNKTCGSGEVCAVEDGYQGCFPKRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKT-- 742
Query: 107 LGVSTQGLTPFTVTTKNENRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALP 166
+ N+ + + +++R + + + I +V++NG LP
Sbjct: 743 ----CPERPEYLEIDINKKKPDAGPAWLRGLRILVADQEVKIGGIGASEVKLNGQEVELP 798
Query: 167 VSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNN 226
G++ + + + + + + V Y + + L ++Y GLCG + N ++
Sbjct: 799 FFHPSGKLEIYRNKNSTTVESKGVVTVQYSDIGLLYIRLSTTYFNCTGGLCGFYNANASD 858
Query: 227 DQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDR--LEQYEGPGFCGPLA 284
+ PNG ++ ++ SW ++ +C EC C D L+ Y CG +
Sbjct: 859 EFCLPNGKCTDNLAVFLESWTT--FEEICNGECGDLLKACNNDSELLKFYRSRSRCGIIN 916
Query: 285 PGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVVIEDWRA 344
+ F CH V ++++ C+ +C GG+ LC ++A Y +AC+ A V + WR
Sbjct: 917 DPSNSSFLECHGVVNVTAYYRTCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRT 976
Query: 345 QVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVP 404
C + CPENSH+E C C +C + LT +C C EGCQCD G+ L +CV
Sbjct: 977 YDFCPLECPENSHFEEC-ITCTETCET---LTLGPICVDSCSEGCQCDEGYALLGSQCVT 1032
Query: 405 LNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQH 464
+ CGC G FW D C +C C + C C E C + G +
Sbjct: 1033 RSE-CGCNFEGHQLATNETFWVDLDCQIFCYCSGTDNRVHCETIPCKDDEYC-MEEGGLY 1090
Query: 465 GCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGA-ENFTVTVANEHR 523
CQ + A C G HY+T DG FDFQ +C +L P + F VT NE R
Sbjct: 1091 YCQARTDASCIVSGYGHYLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNEDR 1150
Query: 524 GSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQL-DSLLHAHLSGADVVVT 582
+ + V + ++ +S+ + + + V+ + LP +L ++ G VVV
Sbjct: 1151 DPSLALWVKQVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVE 1210
Query: 583 TTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQ-- 640
T GL + +D +F+ + VP + S GLCG YN +P DDL+ G A Q
Sbjct: 1211 TDFGLKVVYDWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSW 1270
Query: 641 ---------GCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYF 691
GCG+ CPS E C +I + + CH V P ++
Sbjct: 1271 VKRDTFCQVGCGD----RCPSCAKVEGFSKV--QQLCSLIPNQNAAFSKCHSKVNPTFFY 1324
Query: 692 QGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDS 751
+ CL D+C G C + Y + CQ G + WR C + CP +SHYE C
Sbjct: 1325 KNCLFDSCIDGGAVQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSV 1384
Query: 752 CPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGP 811
C C ++ C C EGC CDAG+VL+G +C+ CGC DG+YY ++F+
Sbjct: 1385 CQPRCAAIRLKSDCSHYCVEGCHCDAGYVLNGKSCILPHSCGCYSDGKYYEPKQLFW-NS 1443
Query: 812 ECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRV 871
+C RRC C + C + C EEC L +GV+ C +T CLA GG + T DG
Sbjct: 1444 DCTRRCRCFRRNVIQC-DPRQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAF 1502
Query: 872 YDLHGSCSYVLAQVCHPKPGDEDFSIVL--EKNAAGDL---QRLLVTVAGQVVSLAQGQQ 926
+C++VL+ +C P D F +++ +K +A +L + + + + +
Sbjct: 1503 LRFPANCAFVLSTICQKLP-DISFQLIINFDKWSAPNLTIISPVYFYINEEQILINDRNT 1561
Query: 927 VTVDGEAVALPVAVG-RVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGL 985
V V+G V +P G ++ + +V+ T+ +++ ++G + +SI + ++CGL
Sbjct: 1562 VKVNGTQVNVPFITGLATKIYSSEGFLVIDTSPDIQIYYNGFNVIKISISERLQNKVCGL 1621
Query: 986 CGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSK-----GCGEGCGPQGCPVCLAEE 1040
CGNFNG+ +DD+V G S +W+ G K C E Q +C
Sbjct: 1622 CGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKTNGMQKRPLAPSCNELQFSQYAAMCDNVH 1681
Query: 1041 TAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAA 1100
+ + C +L + +G F C +L P ++ C D C K LC SLAAY A
Sbjct: 1682 IQKMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYLDGC-YSHKKFQLCGSLAAYGEA 1740
Query: 1101 CQAAGVAVKPWRTDSFC 1117
C++ G+ W C
Sbjct: 1741 CRSFGILSTEWIEKENC 1757
Score = 307 bits (787), Expect = 4e-83
Identities = 193/611 (31%), Positives = 290/611 (47%), Gaps = 29/611 (4%)
Query: 793 GCLHDGRYYPLGEVFYPGPECERRCECGP-GGHVTCQEGAACGPHEECRLEDGVQACHAT 851
GC G++ GEVF+ C +C C + CQE A+C P+E C + C A
Sbjct: 259 GCTSRGQFLRRGEVFWDDLNCTVKCRCLDFNNEIYCQE-ASCSPYEVCEPKGKFFYCSAV 317
Query: 852 GCGRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEK-----NAAGD 906
C+ G HY T DG ++ GSC+Y+LA+ C FS+ + +A
Sbjct: 318 ETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHRRGSAVSW 377
Query: 907 LQRLLVTVAGQVVSLAQGQ--QVTVDGEAVALPVA--VGRVRVTAEGRNMVLQTTKGLRL 962
++ L V V G + + +G +V V+ +LPV +G V++ G + ++T GL +
Sbjct: 378 VKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQSGISTAVETDFGLLV 437
Query: 963 LFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSK 1022
FDG + +S+P + CGLCGN+N N DDF+ P+G A SV G +WRV +
Sbjct: 438 TFDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHADW 497
Query: 1023 GCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCA 1082
C GC C C A A Y ++ CG L GP C V+ P+ + CVYDLC+
Sbjct: 498 KCDSGC-VDNCTQCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLCS 556
Query: 1083 QKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFC--PLHCPAHSHYSICTRTCQGSCAA 1140
+ + LC+++ AY CQA G+ + WRT + C + CP+ SHYS+CT +C +C+
Sbjct: 557 VRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSSCPDTCSD 616
Query: 1141 LSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSL-LTSDCSERCS 1199
L+ C T C EGCEC+ F+LS C+P+ CGC +G Y + T++C+ +C
Sbjct: 617 LTASRNCATPCTEGCECNQGFVLSTSQCVPLHKCGCDFDGHYYTMGEFFWATANCTVQCL 676
Query: 1200 CSSSSGLTCQAAGCPPGRVCEVKAEARNCWATR-GLCVLSVGANLTTFDGARGATTSPGV 1258
C + C C G VC V+ + C+ R +C+LS L TFDGA A S
Sbjct: 677 CEEGGDVYCFNKTCGSGEVCAVEDGYQGCFPKRETVCLLSQNQVLHTFDGASYAFPSEFS 736
Query: 1259 YELSSRCPGLQNTIPWYRVVAEVQICHGKTEA----VGQVHIFFQDGMVTL--TPNKGVW 1312
Y L CP P Y E+ I K +A + + I D V + V
Sbjct: 737 YTLLKTCP----ERPEY---LEIDINKKKPDAGPAWLRGLRILVADQEVKIGGIGASEVK 789
Query: 1313 VNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGAC 1372
+NG V+LP + S V K V V G + + +S + G C
Sbjct: 790 LNGQEVELPFFHPSGKLEIYRNKNSTTVESKGVVTVQYSDIGLLYIRLSTTYFNCTGGLC 849
Query: 1373 GNFDGDQTNDW 1383
G ++ + ++++
Sbjct: 850 GFYNANASDEF 860
>gi|16554449 zonadhesin isoform 3 [Homo sapiens]
Length = 2812
Score = 686 bits (1769), Expect = 0.0
Identities = 449/1392 (32%), Positives = 655/1392 (47%), Gaps = 96/1392 (6%)
Query: 47 CHGVTCRPQETCKEQGGQGVCLPNY-EATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTG 105
C C C+ + GQ C P ATC ++GDPHY +FDGR F F G C Y+LA
Sbjct: 1127 CQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQP- 1185
Query: 106 CLGVSTQGLTPFTVTTKNENRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTAL 165
G ST F VT KNE +G VS + V V + +++ K + V G L
Sbjct: 1186 -CGNSTDPF--FRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGR--RTLVGGQQVTL 1240
Query: 166 PVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPN 225
P + G A G L +FGL+V +D + ++ VT+ S+Y G +CGLCGN D N +
Sbjct: 1241 PAIPSKGVFLGASGRFVELQT-EFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSD 1299
Query: 226 NDQVFPNGTLAPSIPIWGGSWRAP-GWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLA 284
ND + +G+ A G SW+ D C + P+C GPGFCG L
Sbjct: 1300 NDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLV 1359
Query: 285 PGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVVIEDWRA 344
T GPF TC HV SFF C+LD+C G +LC +++ CQ AG ++ WR
Sbjct: 1360 D-THGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWRE 1418
Query: 345 QVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVP 404
C + CP NS Y +C PCP +C S + C CVE C+C+ GFVLS C+P
Sbjct: 1419 PHFCPMACPPNSKYSLCAKPCPDTCHSG---FSGMFCSDRCVEACECNPGFVLSGLECIP 1475
Query: 405 LNNGCGC-WANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQ 463
+ CGC G+Y + G ++ G C + C C + C P C E CG G
Sbjct: 1476 -RSQCGCLHPAGSYFKVGERWYKPG-CKELCVC-ESNNRIRCQPWRCRAQEFCG-QQDGI 1531
Query: 464 HGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHR 523
+GC A C A GDPHY+T DG F GTC Y+L+ PC + F V+ NE+R
Sbjct: 1532 YGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDS-YFVVSATNENR 1590
Query: 524 GS-QAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQL-DSLLHAHLSGADVVV 581
G VSY ++V + +++ S++L K+ ++G VALP L + LS V++
Sbjct: 1591 GGILEVSYIKAVHVTVFDLSISLLRGC--KVMLNGHRVALPVWLAQGRVTIRLSSNLVLL 1648
Query: 582 TTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAG--WQVGGA 639
T GL + +DG V + VP++Y LCGLCGNYN + DD K AG Q+G A
Sbjct: 1649 YTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAA 1708
Query: 640 QGCGECVSKPC------PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQG 693
E C PS C E + C ++ GP + CH +VPP F
Sbjct: 1709 WKLPESSEPGCFLVGGKPSSC-QENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFAS 1767
Query: 694 CLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCP 753
C+ C +G LC ++ Y + C AG Q WR FCP++CP S Y C CP
Sbjct: 1768 CVHGQCGTKGDTTALCRSLQAYASLCAQAG-QAPAWRNRTFCPMRCPPGSSYSPCSSPCP 1826
Query: 754 VSCPSLSAPEGCESA--CREGCVCDAGFVLSGDTCVPVGQCGCLHD-GRYYPLGEVFYPG 810
+C S++ P C A C E C C G +LSG +CVP+GQCGC G Y+P+GE +Y
Sbjct: 1827 DTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTE 1886
Query: 811 PECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGR 870
C R C C ++TC + + C P++ C DG+ C A+G G C G HY++ DG
Sbjct: 1887 NTCTRLCTCSVHNNITCFQ-STCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGS 1945
Query: 871 VYDLHGSCSYVLAQVCHPKPGDEDFSIVL--EKNAAGD----LQRLLVTVAGQVVSLAQG 924
+ + +C+ VL +VCHP F I EK G L + + + V+L +G
Sbjct: 1946 NHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQKG 2005
Query: 925 QQVTVDGEAVALPV--AVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRL 982
+V ++ + V LP + V V + ++ G+++ FDG+ L + IP+ + G++
Sbjct: 2006 HRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKV 2065
Query: 983 CGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEGCGPQGCPVCLAEETA 1042
CG+CGNFN D+ ++P+ A+S F +W+ C + + E+
Sbjct: 2066 CGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQS--------LLVDEQQI 2117
Query: 1043 PYE----------------SNEAC-GQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKG 1085
P E + E C LR P +A C + + + + C LC G
Sbjct: 2118 PAEQQENPSGNCRAADLRRAREKCEAALRAP--VWAQCASRIDLTPFLVDCANTLCEFGG 2175
Query: 1086 DKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGL- 1144
LC++L A+ A CQ+ G+ WR SFCPL CPA+S Y+ C +C SC L G
Sbjct: 2176 LYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRC 2235
Query: 1145 --TGCTTRCFEGCECDDRFLLSQGVCIPVQDCGCTH-NGRYLPVNSSLLTSDCSERCSCS 1201
+ C EGC C ++LS+ C+P CGC +G +P+ S ++S C+E+C C+
Sbjct: 2236 EGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCT 2295
Query: 1202 SSSGLTCQAAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYEL 1261
+ + C CP G C++ ++ N CV + + R T Y L
Sbjct: 2296 GGA-IQCGDFRCPSGSHCQLTSDNSN-----SNCVSDKSEQCSVYGDPRYLTFDGFSYRL 2349
Query: 1262 SSRCP-GLQNTIPWYRVVAEVQICHGKTEA-VGQVHIFFQDGMVTLTPNKGVWVNGLRVD 1319
R L T+ E + G+ + + IF Q+ + T+ K GL +
Sbjct: 2350 QGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELV 2409
Query: 1320 LPAEKLASVSVSRTPDGSLLVR---------QKAGVQVWLGANGKVAVIVSNDHAGKLCG 1370
+ +K+A V P+ L V + V G + + + + G + G
Sbjct: 2410 VNNQKMA---VPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSG 2466
Query: 1371 ACGNFDGDQTND 1382
CGN+D ++ ND
Sbjct: 2467 LCGNYDKNRKND 2478
Score = 647 bits (1669), Expect = 0.0
Identities = 392/1088 (36%), Positives = 550/1088 (50%), Gaps = 63/1088 (5%)
Query: 352 CPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGC 411
CP N+ YE C CPASC SP P P C EGC C+ GF+ S + C+ ++ C C
Sbjct: 1044 CPPNARYESCA--CPASCKSPRPSCGPL-----CREGCVCNPGFLFSDNHCIQASS-CNC 1095
Query: 412 WANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVS- 470
+ N Y+E G+E W C++ CRC PG + C + CG VC L +GQ+GC P +
Sbjct: 1096 FYNNDYYEPGAE-WFSPNCTEHCRCWPGS-RVECQISQCGTHTVCQL-KNGQYGCHPYAG 1152
Query: 471 TAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSY 530
TA C +GDPHYVT DG F F G C Y+L+ PC F VT NE +G + VS
Sbjct: 1153 TATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNST--DPFFRVTAKNEEQGQEGVSC 1210
Query: 531 TRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLA 590
V + + ++TL R+ V G V LP + SG V + T GL +
Sbjct: 1211 LSKVYVTLPESTVTLLKG--RRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVR 1268
Query: 591 FDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAG--------WQVGGA--Q 640
+DGD + + V + Y+ LCGLCGNY+ + +D + G PAG WQ Q
Sbjct: 1269 WDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQ 1328
Query: 641 GCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQ 700
C + PS C Q S GP CG + T GP C V A +F C+LD C
Sbjct: 1329 ECQKYQVVNSPS-CDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCG 1387
Query: 701 VQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLS 760
QG LC ++T CQ AG + WR P FCP+ CP +S Y LC CP +C S
Sbjct: 1388 FQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSGF 1447
Query: 761 APEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHD-GRYYPLGEVFYPGPECERRCEC 819
+ C C E C C+ GFVLSG C+P QCGCLH G Y+ +GE +Y P C+ C C
Sbjct: 1448 SGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYK-PGCKELCVC 1506
Query: 820 GPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCS 879
+ CQ C E C +DG+ CHA G C A+G HY+T DG ++ G+C+
Sbjct: 1507 ESNNRIRCQPW-RCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCT 1565
Query: 880 YVLAQVCHPKPGDEDFSI-VLEKNAAGDLQ-----RLLVTVAGQVVSLAQGQQVTVDGEA 933
YVL + C + D F + +N G L+ + VTV +SL +G +V ++G
Sbjct: 1566 YVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHR 1625
Query: 934 VALPV--AVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNG 991
VALPV A GRV + ++L T GL++ +DG + +++PS + G+LCGLCGN+N
Sbjct: 1626 VALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNN 1685
Query: 992 NWSDDFVLPNGSAASSVETFGAAWRVPGSSK-GCG-EGCGPQGCPVCLAEETAPYESNEA 1049
N DD + P+ A GAAW++P SS+ GC G P C E + N+
Sbjct: 1686 NSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSC----QENSMADAWNKN 1741
Query: 1050 CGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVK 1109
C L NPQGPF+ C V+ P F CV+ C KGD LCRSL AY + C AG A
Sbjct: 1742 CAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQA-P 1800
Query: 1110 PWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGC--TTRCFEGCECDDRFLLSQGV 1167
WR +FCP+ CP S YS C+ C +C++++ C C E CEC +LS
Sbjct: 1801 AWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTS 1860
Query: 1168 CIPVQDCGCTH-NGRYLPVNSSLLTSD-CSERCSCSSSSGLTCQAAGCPPGRVCEVKAEA 1225
C+P+ CGCT G Y PV T + C+ C+CS + +TC + C P ++C
Sbjct: 1861 CVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGL 1920
Query: 1226 RNCWATR-GLCVLSVGANLTTFDGARGATTSPGVYELSSRC-PGLQNTIPWYRVVAEVQI 1283
C A+ G+C L ++ +FDG+ + L C P + +P++++ A+ +
Sbjct: 1921 LRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAM--ALPFFKISAKHEK 1978
Query: 1284 CHGKTEA--VGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPA-EKLASVSVSRTPDGSLLV 1340
G TEA + +V+I D VTL V +N +V LPA ++ VSV + S +V
Sbjct: 1979 EEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYS-IV 2037
Query: 1341 RQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHDSQEKPA------MEK 1394
K GVQV N + + + + GK+CG CGNF+ ++ ++ ++ A +
Sbjct: 2038 NIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNS 2097
Query: 1395 WRAQDFSP 1402
W+ +D P
Sbjct: 2098 WKDKDIDP 2105
Score = 561 bits (1446), Expect = e-159
Identities = 391/1243 (31%), Positives = 573/1243 (46%), Gaps = 109/1243 (8%)
Query: 47 CHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGC 106
C CR QE C +Q G C ATC GDPHY +FDG F GTC YVL T C
Sbjct: 1514 CQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVL-TRPC 1572
Query: 107 LGVSTQGLTPFTVTTKNENRGNPA-VSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTAL 165
S F V+ NENRG VSY++ V V +IS+ + KV +NG AL
Sbjct: 1573 WSRSQDSY--FVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRG--CKVMLNGHRVAL 1628
Query: 166 PVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPN 225
PV +A GR+++ ++ LL +FGLQV YD + V+VT+PSSY G +CGLCGN + N
Sbjct: 1629 PVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSL 1688
Query: 226 NDQVFPNGTLAPSIPIWGGSWRAP-GWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLA 284
+D + P+ LA G +W+ P +P C+ G +C E+ + +
Sbjct: 1689 DDNLRPDRKLAGDSMQLGAAWKLPESSEPGCF-LVGGKPSSCQENSMADAWNKNCAILIN 1747
Query: 285 PGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVVIEDWRA 344
P GPF+ CH VPP+S F CV C GD LC++L +Y + C AG WR
Sbjct: 1748 PQ--GPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQA-PAWRN 1804
Query: 345 QVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEG--PCVEGCQCDAGFVLSADRC 402
+ C + CP S Y C PCP +C S + P C PC E C+C G +LS C
Sbjct: 1805 RTFCPMRCPPGSSYSPCSSPCPDTCSS---INNPRDCPKALPCAESCECQKGHILSGTSC 1861
Query: 403 VPLNNGCGCW-ANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPS 461
VPL CGC G+YH G ++ + TC++ C C ++ C ++C ++C L
Sbjct: 1862 VPLGQ-CGCTDPAGSYHPVGERWYTENTCTRLCTCSVHN-NITCFQSTCKPNQICWAL-D 1918
Query: 462 GQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANE 521
G C+ CQ G+ HYV+ DG C +L CH P + F ++ +E
Sbjct: 1919 GLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCH-PAMALPFFKISAKHE 1977
Query: 522 -HRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADV- 579
G V + IY+ +TL ++ ++ V LP + + + + +
Sbjct: 1978 KEEGGTEAFRLHEVYIDIYDAQVTLQKG--HRVLINSKQVTLP-AISQIPGVSVKSSSIY 2034
Query: 580 -VVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGG 638
+V G+ + FDG+ + + +P Y +CG+CGN+N + D+L + A
Sbjct: 2035 SIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVAN---SD 2091
Query: 639 AQGCGECVSKPCPSPCTP----------EQQESFGGPDACGVI--------SATDGPL-A 679
++ K C EQQE+ G + +A P+ A
Sbjct: 2092 SEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWA 2151
Query: 680 PCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQC 739
C + + C C+ G LC A+ + A CQ+ G + WR FCPL+C
Sbjct: 2152 QCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLEC 2211
Query: 740 PAHSHYELCGDSCPVSCPSLSAP-EGCE--SACREGCVCDAGFVLSGDTCVPVGQCGCLH 796
PA+S Y C SC SC L EG + SAC EGC+C G+VLS D CVP QCGC
Sbjct: 2212 PAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKD 2271
Query: 797 -DGRYYPLGEVFYPGPECERRCECGPGGHVTCQE-GAACGPHEECRLEDGVQACHATGCG 854
G PLG+ + C +C C GG + C + G H + ++ C +
Sbjct: 2272 AHGGSIPLGKSWVSSG-CTEKCVC-TGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSE 2329
Query: 855 RCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGD------LQ 908
+C G Y+T DG Y L G +YVL + P + +V +N LQ
Sbjct: 2330 QCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQ 2389
Query: 909 RLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGR-VRVTAEGRNMVLQTTKGLRLLFDGD 967
++ TV G V L G ++ V+ + +A+P +RVT G+ + L T L + F G
Sbjct: 2390 EVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGR 2449
Query: 968 AHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRV---------- 1017
+ ++S+PS + G + GLCGN++ N +D +LP+G+ ++ TFG +W V
Sbjct: 2450 KNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFP 2509
Query: 1018 ---PGSSKGCGEGCGPQ-GCPV--CLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSE 1071
P +G G G + G V C E+ A S +AC L +PQGPFA C ++P
Sbjct: 2510 RAIPAEEEGQGAELGLRTGLQVSECSPEQLAS-NSTQACRVLADPQGPFAACHQTVAPEP 2568
Query: 1072 YFRQCVYDLCA---QKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYS 1128
+ CV DLC+ + + C+ L+ + GV+ + + + + +
Sbjct: 2569 FQEHCVLDLCSAQDPREQEELRCQVLSGH-------GVSSR----------YHISELYDT 2611
Query: 1129 ICTRTCQ-GSCAALSG-LTGCTTRCFEGCECDDRFLLSQGVCIPVQDCGCTHNGRYLPVN 1186
+ + CQ G L G L G + R L P+ DCGCT NG Y +
Sbjct: 2612 LPSILCQPGRPRGLRGPLRGRLRQ-------HPRLCLQWHPEPPLADCGCTSNGIYYQLG 2664
Query: 1187 SSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCW 1229
SS LT DCS+RC+C+SS L C+ C G VC + + C+
Sbjct: 2665 SSFLTEDCSQRCTCASSRILLCEPFSCRAGEVCTLGNHTQGCF 2707
Score = 376 bits (965), Expect = e-104
Identities = 221/659 (33%), Positives = 316/659 (47%), Gaps = 25/659 (3%)
Query: 738 QCPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHD 797
+CP ++ YE C +CP SC S C CREGCVC+ GF+ S + C+ C C ++
Sbjct: 1043 RCPPNARYESC--ACPASCK--SPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYN 1098
Query: 798 GRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHA-TGCGRC 856
YY G ++ P C C C PG V CQ + CG H C+L++G CH G C
Sbjct: 1099 NDYYEPGAEWF-SPNCTEHCRCWPGSRVECQI-SQCGTHTVCQLKNGQYGCHPYAGTATC 1156
Query: 857 LANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGD-----LQRLL 911
L G HY+T DGR + G C+Y+LAQ C D F + + G L ++
Sbjct: 1157 LVYGDPHYVTFDGRHFGFMGKCTYILAQPC-GNSTDPFFRVTAKNEEQGQEGVSCLSKVY 1215
Query: 912 VTVAGQVVSLAQGQQVTVDGEAVALPVAVGR-VRVTAEGRNMVLQTTKGLRLLFDGDAHL 970
VT+ V+L +G++ V G+ V LP + V + A GR + LQT GLR+ +DGD L
Sbjct: 1216 VTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQL 1275
Query: 971 LMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEGCGP 1030
+++ S + G+LCGLCGN++GN +D + +GS A E G +W+ +
Sbjct: 1276 YVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQV 1335
Query: 1031 QGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFL 1090
P C + + CG+L + GPF TC + + +F C+ D+C +G + L
Sbjct: 1336 VNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLL 1395
Query: 1091 CRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTG--CT 1148
C ++ T CQ AG AVKPWR FCP+ CP +S YS+C + C +C SG +G C+
Sbjct: 1396 CTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCH--SGFSGMFCS 1453
Query: 1149 TRCFEGCECDDRFLLSQGVCIPVQDCGCTH-NGRYLPVNSSLLTSDCSERCSCSSSSGLT 1207
RC E CEC+ F+LS CIP CGC H G Y V C E C C S++ +
Sbjct: 1454 DRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRIR 1513
Query: 1208 CQAAGCPPGRVCEVKAEARNCWAT-RGLCVLSVGANLTTFDGARGATTSPGVYELSSRCP 1266
CQ C C + C A C S + TFDGA Y L+ C
Sbjct: 1514 CQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPC- 1572
Query: 1267 GLQNTIPWYRVVAEVQICHG---KTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAE 1323
+ Y VV+ G + + VH+ D ++L V +NG RV LP
Sbjct: 1573 -WSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVW 1631
Query: 1324 KLASVSVSRTPDGSLLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTND 1382
R +L+ G+QV + V V V + + G+LCG CGN++ + +D
Sbjct: 1632 LAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDD 1690
Score = 137 bits (345), Expect = 7e-32
Identities = 121/423 (28%), Positives = 170/423 (40%), Gaps = 54/423 (12%)
Query: 67 CLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLTPFTVTTKNENR 126
C+ + C ++GDP Y +FDG + QG YVL T + V +G+ P V +N+
Sbjct: 2323 CVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKT--VDVLPEGVEPLLVEGRNKMD 2380
Query: 127 GNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLV 186
+ +++ V G + + ++ VN A+P + + V + LV
Sbjct: 2381 PPRSSIFLQEVITTVYGYKVQLQAGL--ELVVNNQKMAVPYRPNE-HLRVTLWGQRLYLV 2437
Query: 187 ADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSW 246
DF L VS+ ++LPS Y G V GLCGN D+N ND + P+G L ++ +G SW
Sbjct: 2438 TDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSW 2497
Query: 247 RAPGWDPL--------CWDECRGS---------CPTCPEDRLEQYEGPGFCGPLAPGTGG 289
D L +E +G+ C ++L C LA G
Sbjct: 2498 EVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNSTQA-CRVLADPQG- 2555
Query: 290 PFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVVIEDWRAQVGCE 349
PF CH V PE F + CVLD+C + E+ R QV
Sbjct: 2556 PFAACHQTVAPEPFQEHCVLDLCSAQDPREQ-------------------EELRCQVLSG 2596
Query: 350 ITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGC 409
H P+ P P GP + L PL + C
Sbjct: 2597 HGVSSRYHISELYDTLPSILCQPG---RPRGLRGPLRGRLRQHPRLCLQWHPEPPLAD-C 2652
Query: 410 GCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQH--GCQ 467
GC +NG Y++ GS F + CSQ C C L+C P SC GEVC L G H GC
Sbjct: 2653 GCTSNGIYYQLGSSFLTE-DCSQRCTCA-SSRILLCEPFSCRAGEVCTL---GNHTQGCF 2707
Query: 468 PVS 470
P S
Sbjct: 2708 PES 2710
>gi|27881494 zonadhesin isoform 6 [Homo sapiens]
Length = 2721
Score = 686 bits (1769), Expect = 0.0
Identities = 449/1392 (32%), Positives = 655/1392 (47%), Gaps = 96/1392 (6%)
Query: 47 CHGVTCRPQETCKEQGGQGVCLPNY-EATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTG 105
C C C+ + GQ C P ATC ++GDPHY +FDGR F F G C Y+LA
Sbjct: 1127 CQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQP- 1185
Query: 106 CLGVSTQGLTPFTVTTKNENRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTAL 165
G ST F VT KNE +G VS + V V + +++ K + V G L
Sbjct: 1186 -CGNSTDPF--FRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGR--RTLVGGQQVTL 1240
Query: 166 PVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPN 225
P + G A G L +FGL+V +D + ++ VT+ S+Y G +CGLCGN D N +
Sbjct: 1241 PAIPSKGVFLGASGRFVELQT-EFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSD 1299
Query: 226 NDQVFPNGTLAPSIPIWGGSWRAP-GWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLA 284
ND + +G+ A G SW+ D C + P+C GPGFCG L
Sbjct: 1300 NDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLV 1359
Query: 285 PGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVVIEDWRA 344
T GPF TC HV SFF C+LD+C G +LC +++ CQ AG ++ WR
Sbjct: 1360 D-THGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWRE 1418
Query: 345 QVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVP 404
C + CP NS Y +C PCP +C S + C CVE C+C+ GFVLS C+P
Sbjct: 1419 PHFCPMACPPNSKYSLCAKPCPDTCHSG---FSGMFCSDRCVEACECNPGFVLSGLECIP 1475
Query: 405 LNNGCGC-WANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQ 463
+ CGC G+Y + G ++ G C + C C + C P C E CG G
Sbjct: 1476 -RSQCGCLHPAGSYFKVGERWYKPG-CKELCVC-ESNNRIRCQPWRCRAQEFCG-QQDGI 1531
Query: 464 HGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHR 523
+GC A C A GDPHY+T DG F GTC Y+L+ PC + F V+ NE+R
Sbjct: 1532 YGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDS-YFVVSATNENR 1590
Query: 524 GS-QAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQL-DSLLHAHLSGADVVV 581
G VSY ++V + +++ S++L K+ ++G VALP L + LS V++
Sbjct: 1591 GGILEVSYIKAVHVTVFDLSISLLRGC--KVMLNGHRVALPVWLAQGRVTIRLSSNLVLL 1648
Query: 582 TTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAG--WQVGGA 639
T GL + +DG V + VP++Y LCGLCGNYN + DD K AG Q+G A
Sbjct: 1649 YTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAA 1708
Query: 640 QGCGECVSKPC------PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQG 693
E C PS C E + C ++ GP + CH +VPP F
Sbjct: 1709 WKLPESSEPGCFLVGGKPSSC-QENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFAS 1767
Query: 694 CLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCP 753
C+ C +G LC ++ Y + C AG Q WR FCP++CP S Y C CP
Sbjct: 1768 CVHGQCGTKGDTTALCRSLQAYASLCAQAG-QAPAWRNRTFCPMRCPPGSSYSPCSSPCP 1826
Query: 754 VSCPSLSAPEGCESA--CREGCVCDAGFVLSGDTCVPVGQCGCLHD-GRYYPLGEVFYPG 810
+C S++ P C A C E C C G +LSG +CVP+GQCGC G Y+P+GE +Y
Sbjct: 1827 DTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTE 1886
Query: 811 PECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGR 870
C R C C ++TC + + C P++ C DG+ C A+G G C G HY++ DG
Sbjct: 1887 NTCTRLCTCSVHNNITCFQ-STCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGS 1945
Query: 871 VYDLHGSCSYVLAQVCHPKPGDEDFSIVL--EKNAAGD----LQRLLVTVAGQVVSLAQG 924
+ + +C+ VL +VCHP F I EK G L + + + V+L +G
Sbjct: 1946 NHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQKG 2005
Query: 925 QQVTVDGEAVALPV--AVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRL 982
+V ++ + V LP + V V + ++ G+++ FDG+ L + IP+ + G++
Sbjct: 2006 HRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKV 2065
Query: 983 CGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEGCGPQGCPVCLAEETA 1042
CG+CGNFN D+ ++P+ A+S F +W+ C + + E+
Sbjct: 2066 CGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQS--------LLVDEQQI 2117
Query: 1043 PYE----------------SNEAC-GQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKG 1085
P E + E C LR P +A C + + + + C LC G
Sbjct: 2118 PAEQQENPSGNCRAADLRRAREKCEAALRAP--VWAQCASRIDLTPFLVDCANTLCEFGG 2175
Query: 1086 DKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGL- 1144
LC++L A+ A CQ+ G+ WR SFCPL CPA+S Y+ C +C SC L G
Sbjct: 2176 LYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRC 2235
Query: 1145 --TGCTTRCFEGCECDDRFLLSQGVCIPVQDCGCTH-NGRYLPVNSSLLTSDCSERCSCS 1201
+ C EGC C ++LS+ C+P CGC +G +P+ S ++S C+E+C C+
Sbjct: 2236 EGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCT 2295
Query: 1202 SSSGLTCQAAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYEL 1261
+ + C CP G C++ ++ N CV + + R T Y L
Sbjct: 2296 GGA-IQCGDFRCPSGSHCQLTSDNSN-----SNCVSDKSEQCSVYGDPRYLTFDGFSYRL 2349
Query: 1262 SSRCP-GLQNTIPWYRVVAEVQICHGKTEA-VGQVHIFFQDGMVTLTPNKGVWVNGLRVD 1319
R L T+ E + G+ + + IF Q+ + T+ K GL +
Sbjct: 2350 QGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELV 2409
Query: 1320 LPAEKLASVSVSRTPDGSLLVR---------QKAGVQVWLGANGKVAVIVSNDHAGKLCG 1370
+ +K+A V P+ L V + V G + + + + G + G
Sbjct: 2410 VNNQKMA---VPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSG 2466
Query: 1371 ACGNFDGDQTND 1382
CGN+D ++ ND
Sbjct: 2467 LCGNYDKNRKND 2478
Score = 647 bits (1669), Expect = 0.0
Identities = 392/1088 (36%), Positives = 550/1088 (50%), Gaps = 63/1088 (5%)
Query: 352 CPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGC 411
CP N+ YE C CPASC SP P P C EGC C+ GF+ S + C+ ++ C C
Sbjct: 1044 CPPNARYESCA--CPASCKSPRPSCGPL-----CREGCVCNPGFLFSDNHCIQASS-CNC 1095
Query: 412 WANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVS- 470
+ N Y+E G+E W C++ CRC PG + C + CG VC L +GQ+GC P +
Sbjct: 1096 FYNNDYYEPGAE-WFSPNCTEHCRCWPGS-RVECQISQCGTHTVCQL-KNGQYGCHPYAG 1152
Query: 471 TAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSY 530
TA C +GDPHYVT DG F F G C Y+L+ PC F VT NE +G + VS
Sbjct: 1153 TATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNST--DPFFRVTAKNEEQGQEGVSC 1210
Query: 531 TRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLA 590
V + + ++TL R+ V G V LP + SG V + T GL +
Sbjct: 1211 LSKVYVTLPESTVTLLKG--RRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVR 1268
Query: 591 FDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAG--------WQVGGA--Q 640
+DGD + + V + Y+ LCGLCGNY+ + +D + G PAG WQ Q
Sbjct: 1269 WDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQ 1328
Query: 641 GCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQ 700
C + PS C Q S GP CG + T GP C V A +F C+LD C
Sbjct: 1329 ECQKYQVVNSPS-CDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCG 1387
Query: 701 VQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLS 760
QG LC ++T CQ AG + WR P FCP+ CP +S Y LC CP +C S
Sbjct: 1388 FQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSGF 1447
Query: 761 APEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHD-GRYYPLGEVFYPGPECERRCEC 819
+ C C E C C+ GFVLSG C+P QCGCLH G Y+ +GE +Y P C+ C C
Sbjct: 1448 SGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYK-PGCKELCVC 1506
Query: 820 GPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCS 879
+ CQ C E C +DG+ CHA G C A+G HY+T DG ++ G+C+
Sbjct: 1507 ESNNRIRCQPW-RCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCT 1565
Query: 880 YVLAQVCHPKPGDEDFSI-VLEKNAAGDLQ-----RLLVTVAGQVVSLAQGQQVTVDGEA 933
YVL + C + D F + +N G L+ + VTV +SL +G +V ++G
Sbjct: 1566 YVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHR 1625
Query: 934 VALPV--AVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNG 991
VALPV A GRV + ++L T GL++ +DG + +++PS + G+LCGLCGN+N
Sbjct: 1626 VALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNN 1685
Query: 992 NWSDDFVLPNGSAASSVETFGAAWRVPGSSK-GCG-EGCGPQGCPVCLAEETAPYESNEA 1049
N DD + P+ A GAAW++P SS+ GC G P C E + N+
Sbjct: 1686 NSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSC----QENSMADAWNKN 1741
Query: 1050 CGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVK 1109
C L NPQGPF+ C V+ P F CV+ C KGD LCRSL AY + C AG A
Sbjct: 1742 CAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQA-P 1800
Query: 1110 PWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGC--TTRCFEGCECDDRFLLSQGV 1167
WR +FCP+ CP S YS C+ C +C++++ C C E CEC +LS
Sbjct: 1801 AWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTS 1860
Query: 1168 CIPVQDCGCTH-NGRYLPVNSSLLTSD-CSERCSCSSSSGLTCQAAGCPPGRVCEVKAEA 1225
C+P+ CGCT G Y PV T + C+ C+CS + +TC + C P ++C
Sbjct: 1861 CVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGL 1920
Query: 1226 RNCWATR-GLCVLSVGANLTTFDGARGATTSPGVYELSSRC-PGLQNTIPWYRVVAEVQI 1283
C A+ G+C L ++ +FDG+ + L C P + +P++++ A+ +
Sbjct: 1921 LRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAM--ALPFFKISAKHEK 1978
Query: 1284 CHGKTEA--VGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPA-EKLASVSVSRTPDGSLLV 1340
G TEA + +V+I D VTL V +N +V LPA ++ VSV + S +V
Sbjct: 1979 EEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYS-IV 2037
Query: 1341 RQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHDSQEKPA------MEK 1394
K GVQV N + + + + GK+CG CGNF+ ++ ++ ++ A +
Sbjct: 2038 NIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNS 2097
Query: 1395 WRAQDFSP 1402
W+ +D P
Sbjct: 2098 WKDKDIDP 2105
Score = 541 bits (1393), Expect = e-153
Identities = 362/1133 (31%), Positives = 527/1133 (46%), Gaps = 83/1133 (7%)
Query: 47 CHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGC 106
C CR QE C +Q G C ATC GDPHY +FDG F GTC YVL T C
Sbjct: 1514 CQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVL-TRPC 1572
Query: 107 LGVSTQGLTPFTVTTKNENRGNPA-VSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTAL 165
S F V+ NENRG VSY++ V V +IS+ + KV +NG AL
Sbjct: 1573 WSRSQDSY--FVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRG--CKVMLNGHRVAL 1628
Query: 166 PVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPN 225
PV +A GR+++ ++ LL +FGLQV YD + V+VT+PSSY G +CGLCGN + N
Sbjct: 1629 PVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSL 1688
Query: 226 NDQVFPNGTLAPSIPIWGGSWRAP-GWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLA 284
+D + P+ LA G +W+ P +P C+ G +C E+ + +
Sbjct: 1689 DDNLRPDRKLAGDSMQLGAAWKLPESSEPGCF-LVGGKPSSCQENSMADAWNKNCAILIN 1747
Query: 285 PGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVVIEDWRA 344
P GPF+ CH VPP+S F CV C GD LC++L +Y + C AG WR
Sbjct: 1748 PQ--GPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQA-PAWRN 1804
Query: 345 QVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEG--PCVEGCQCDAGFVLSADRC 402
+ C + CP S Y C PCP +C S + P C PC E C+C G +LS C
Sbjct: 1805 RTFCPMRCPPGSSYSPCSSPCPDTCSS---INNPRDCPKALPCAESCECQKGHILSGTSC 1861
Query: 403 VPLNNGCGCW-ANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPS 461
VPL CGC G+YH G ++ + TC++ C C ++ C ++C ++C L
Sbjct: 1862 VPLGQ-CGCTDPAGSYHPVGERWYTENTCTRLCTCSVHN-NITCFQSTCKPNQICWAL-D 1918
Query: 462 GQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANE 521
G C+ CQ G+ HYV+ DG C +L CH P + F ++ +E
Sbjct: 1919 GLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCH-PAMALPFFKISAKHE 1977
Query: 522 -HRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADV- 579
G V + IY+ +TL ++ ++ V LP + + + + +
Sbjct: 1978 KEEGGTEAFRLHEVYIDIYDAQVTLQKG--HRVLINSKQVTLP-AISQIPGVSVKSSSIY 2034
Query: 580 -VVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGG 638
+V G+ + FDG+ + + +P Y +CG+CGN+N + D+L + A
Sbjct: 2035 SIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVAN---SD 2091
Query: 639 AQGCGECVSKPCPSPCTP----------EQQESFGGPDACGVI--------SATDGPL-A 679
++ K C EQQE+ G + +A P+ A
Sbjct: 2092 SEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWA 2151
Query: 680 PCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQC 739
C + + C C+ G LC A+ + A CQ+ G + WR FCPL+C
Sbjct: 2152 QCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLEC 2211
Query: 740 PAHSHYELCGDSCPVSCPSLSAP-EGCE--SACREGCVCDAGFVLSGDTCVPVGQCGCLH 796
PA+S Y C SC SC L EG + SAC EGC+C G+VLS D CVP QCGC
Sbjct: 2212 PAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKD 2271
Query: 797 -DGRYYPLGEVFYPGPECERRCECGPGGHVTCQE-GAACGPHEECRLEDGVQACHATGCG 854
G PLG+ + C +C C GG + C + G H + ++ C +
Sbjct: 2272 AHGGSIPLGKSWVSSG-CTEKCVC-TGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSE 2329
Query: 855 RCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGD------LQ 908
+C G Y+T DG Y L G +YVL + P + +V +N LQ
Sbjct: 2330 QCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQ 2389
Query: 909 RLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGR-VRVTAEGRNMVLQTTKGLRLLFDGD 967
++ TV G V L G ++ V+ + +A+P +RVT G+ + L T L + F G
Sbjct: 2390 EVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGR 2449
Query: 968 AHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRV---------- 1017
+ ++S+PS + G + GLCGN++ N +D +LP+G+ ++ TFG +W V
Sbjct: 2450 KNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFP 2509
Query: 1018 ---PGSSKGCGEGCGPQ-GCPV--CLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSE 1071
P +G G G + G V C E+ A S +AC L +PQGPFA C ++P
Sbjct: 2510 RAIPAEEEGQGAELGLRTGLQVSECSPEQLAS-NSTQACRVLADPQGPFAACHQTVAPEP 2568
Query: 1072 YFRQCVYDLCA---QKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHC 1121
+ CV DLC+ + + C+ L+ Y CQ AG A+ WR + C C
Sbjct: 2569 FQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCESPC 2621
Score = 376 bits (965), Expect = e-104
Identities = 221/659 (33%), Positives = 316/659 (47%), Gaps = 25/659 (3%)
Query: 738 QCPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHD 797
+CP ++ YE C +CP SC S C CREGCVC+ GF+ S + C+ C C ++
Sbjct: 1043 RCPPNARYESC--ACPASCK--SPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYN 1098
Query: 798 GRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHA-TGCGRC 856
YY G ++ P C C C PG V CQ + CG H C+L++G CH G C
Sbjct: 1099 NDYYEPGAEWF-SPNCTEHCRCWPGSRVECQI-SQCGTHTVCQLKNGQYGCHPYAGTATC 1156
Query: 857 LANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGD-----LQRLL 911
L G HY+T DGR + G C+Y+LAQ C D F + + G L ++
Sbjct: 1157 LVYGDPHYVTFDGRHFGFMGKCTYILAQPC-GNSTDPFFRVTAKNEEQGQEGVSCLSKVY 1215
Query: 912 VTVAGQVVSLAQGQQVTVDGEAVALPVAVGR-VRVTAEGRNMVLQTTKGLRLLFDGDAHL 970
VT+ V+L +G++ V G+ V LP + V + A GR + LQT GLR+ +DGD L
Sbjct: 1216 VTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQL 1275
Query: 971 LMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEGCGP 1030
+++ S + G+LCGLCGN++GN +D + +GS A E G +W+ +
Sbjct: 1276 YVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQV 1335
Query: 1031 QGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFL 1090
P C + + CG+L + GPF TC + + +F C+ D+C +G + L
Sbjct: 1336 VNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLL 1395
Query: 1091 CRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTG--CT 1148
C ++ T CQ AG AVKPWR FCP+ CP +S YS+C + C +C SG +G C+
Sbjct: 1396 CTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCH--SGFSGMFCS 1453
Query: 1149 TRCFEGCECDDRFLLSQGVCIPVQDCGCTH-NGRYLPVNSSLLTSDCSERCSCSSSSGLT 1207
RC E CEC+ F+LS CIP CGC H G Y V C E C C S++ +
Sbjct: 1454 DRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRIR 1513
Query: 1208 CQAAGCPPGRVCEVKAEARNCWAT-RGLCVLSVGANLTTFDGARGATTSPGVYELSSRCP 1266
CQ C C + C A C S + TFDGA Y L+ C
Sbjct: 1514 CQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPC- 1572
Query: 1267 GLQNTIPWYRVVAEVQICHG---KTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAE 1323
+ Y VV+ G + + VH+ D ++L V +NG RV LP
Sbjct: 1573 -WSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVW 1631
Query: 1324 KLASVSVSRTPDGSLLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTND 1382
R +L+ G+QV + V V V + + G+LCG CGN++ + +D
Sbjct: 1632 LAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDD 1690
Score = 133 bits (335), Expect = 1e-30
Identities = 91/309 (29%), Positives = 137/309 (44%), Gaps = 27/309 (8%)
Query: 67 CLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLTPFTVTTKNENR 126
C+ + C ++GDP Y +FDG + QG YVL T + V +G+ P V +N+
Sbjct: 2323 CVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKT--VDVLPEGVEPLLVEGRNKMD 2380
Query: 127 GNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLV 186
+ +++ V G + + ++ VN A+P + + V + LV
Sbjct: 2381 PPRSSIFLQEVITTVYGYKVQLQAGL--ELVVNNQKMAVPYRPNE-HLRVTLWGQRLYLV 2437
Query: 187 ADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSW 246
DF L VS+ ++LPS Y G V GLCGN D+N ND + P+G L ++ +G SW
Sbjct: 2438 TDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSW 2497
Query: 247 RAPGWDPL--------CWDECRGS---------CPTCPEDRLEQYEGPGFCGPLAPGTGG 289
D L +E +G+ C ++L C LA G
Sbjct: 2498 EVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLAS-NSTQACRVLA-DPQG 2555
Query: 290 PFTTCHAHVPPESFFKGCVLDVCMGGG---DHDILCKALASYVAACQAAGVVIEDWRAQV 346
PF CH V PE F + CVLD+C ++ C+ L+ Y CQ AG + WR +
Sbjct: 2556 PFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRT 2615
Query: 347 GCEITCPEN 355
CE C +N
Sbjct: 2616 LCESPCLQN 2624
>gi|239757284 PREDICTED: similar to Fc fragment of IgG binding
protein [Homo sapiens]
Length = 593
Score = 546 bits (1408), Expect = e-155
Identities = 251/256 (98%), Positives = 254/256 (99%)
Query: 21 VDMEGAAMLYNGQPLKVLLPLLSPDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGD 80
VD+EGAA+LYNGQPLKVLLPLLSPDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGD
Sbjct: 318 VDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGD 377
Query: 81 PHYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLTPFTVTTKNENRGNPAVSYVRVVTVA 140
PHYHSFDGRKFDFQGTCNYVLATTGC GVSTQGLTPFTVTTKN+NRGNPAVSYVRVVTVA
Sbjct: 378 PHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVA 437
Query: 141 ALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWR 200
ALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISV QGASKALLVADFGLQVSYDWNWR
Sbjct: 438 ALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWR 497
Query: 201 VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECR 260
VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECR
Sbjct: 498 VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECR 557
Query: 261 GSCPTCPEDRLEQYEG 276
GSCPTCPEDRLEQYEG
Sbjct: 558 GSCPTCPEDRLEQYEG 573
Score = 323 bits (827), Expect = 9e-88
Identities = 192/569 (33%), Positives = 273/569 (47%), Gaps = 101/569 (17%)
Query: 570 LHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGG 629
+ A G+DVV+ T GL +A+D +VR+ VP Y +CGLCGNYN DP DD +
Sbjct: 12 IRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQ---- 67
Query: 630 KPAGWQVGGAQGCGECVSK-----------PCPS---------PCTPEQQESFGGPDACG 669
KP G Q G A G + PCP C PE ++ + + CG
Sbjct: 68 KPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCG 127
Query: 670 VISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEW 729
++S+ GPL+ CH LV P + C+ D C G+ LC + YV+ACQAAG + W
Sbjct: 128 LLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPW 187
Query: 730 RRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPV 789
R FCP++CP +SHYELC D+C + C +LSAP C+ C EGC CD+GF+ +G CVP+
Sbjct: 188 RTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPI 247
Query: 790 GQCGCLHDGRYY-PLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGV--- 845
QCGC H+G YY P V C ++C C G V CQE +C P + C+ G+
Sbjct: 248 QQCGCYHNGVYYEPEQTVLI--DNCRQQCTCHAGKVVVCQE-HSCKPGQVCQPSGGILSC 304
Query: 846 -------------------------------------QACHATGC------------GRC 856
CH C G C
Sbjct: 305 VTKVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQETCKEQGGQGVC 364
Query: 857 LAN--------GGIHYITLDGRVYDLHGSCSYVLAQVCHP---KPGDEDFSIVLEKNAAG 905
L N G HY + DGR +D G+C+YVLA P G F++ + G
Sbjct: 365 LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRG 424
Query: 906 D-----LQRLLVTVAGQVVSLAQGQ--QVTVDGEAVALPVAV--GRVRVTAEGRNMVLQT 956
+ ++ + V G +S+ + + +V V+G ALPV+V GR+ VT +L
Sbjct: 425 NPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVA 484
Query: 957 TKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWR 1016
GL++ +D + + +++PS + G +CGLCGN + N ++D V PNG+ A S+ +G +WR
Sbjct: 485 DFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWR 544
Query: 1017 VPGSSKGCGEGCGPQGCPVCLAEETAPYE 1045
PG C + C CP C + YE
Sbjct: 545 APGWDPLCWDEC-RGSCPTCPEDRLEQYE 572
Score = 322 bits (826), Expect = 1e-87
Identities = 197/583 (33%), Positives = 289/583 (49%), Gaps = 91/583 (15%)
Query: 165 LPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNP 224
LPV +A+G+I +Q S ++ DFGL+V+YD + V VT+P +Y+ +CGLCGN + +P
Sbjct: 3 LPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDP 62
Query: 225 NNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPT----------CPEDRLEQY 274
+D PNG+ A + +G SW D C CP CP + ++Y
Sbjct: 63 KDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPT--PCPPGSEDCIPSHKCPPELEKKY 120
Query: 275 EGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQA 334
+ FCG L+ TG P ++CH V P+ K C+ D+C+GGG+ ILC + +YV+ACQA
Sbjct: 121 QKEEFCGLLSSPTG-PLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQA 179
Query: 335 AGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAG 394
AG +E WR + C + CP NSHYE+C C C + L+ P C+ C EGCQCD+G
Sbjct: 180 AGGHVEPWRTETFCPMECPPNSHYELCADTCSLGC---SALSAPPQCQDGCAEGCQCDSG 236
Query: 395 FVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGE 454
F+ + CVP+ CGC+ NG Y+E D C Q C C G +VC SC G+
Sbjct: 237 FLYNGQACVPIQQ-CGCYHNGVYYEPEQTVLID-NCRQQCTC-HAGKVVVCQEHSCKPGQ 293
Query: 455 VC----------------------------GLLPSGQ--------------HG--CQPVS 470
VC +L +GQ HG C+P
Sbjct: 294 VCQPSGGILSCVTKVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQE 353
Query: 471 T---------------AECQAWGDPHYVTLDGHRFDFQGTCEYLLSAP-CHG-PPLGAEN 513
T A C WGDPHY + DG +FDFQGTC Y+L+ C G G
Sbjct: 354 TCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTP 413
Query: 514 FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQL-DSLLHA 572
FTVT N++RG+ AVSY R VT+ ++++ K++V+GV ALP + D +
Sbjct: 414 FTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISV 473
Query: 573 HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA 632
+ ++ GL +++D + V + +P++Y ++CGLCGN +++P +D G A
Sbjct: 474 TQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLA 533
Query: 633 --------GWQVGGAQG-CGECVSKPCPSPCTPEQQESFGGPD 666
W+ G C + CP+ C ++ E + G D
Sbjct: 534 PSIPIWGGSWRAPGWDPLCWDECRGSCPT-CPEDRLEQYEGLD 575
Score = 255 bits (652), Expect = 2e-67
Identities = 116/303 (38%), Positives = 175/303 (57%), Gaps = 11/303 (3%)
Query: 936 LPVAV--GRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNW 993
LPV + G++R + G ++V++T GLR+ +D ++ +++P + ++CGLCGN+NG+
Sbjct: 3 LPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDP 62
Query: 994 SDDFVLPNGSAASSVETFGAAWR--VPGSSKGCGEGCGPQGCPVCLAEETAP------YE 1045
DDF PNGS A + FG +W VP S C P G C+ P Y+
Sbjct: 63 KDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPC-PPGSEDCIPSHKCPPELEKKYQ 121
Query: 1046 SNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAG 1105
E CG L +P GP ++C ++ P + C++DLC G+ + LC ++ AY +ACQAAG
Sbjct: 122 KEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAG 181
Query: 1106 VAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQ 1165
V+PWRT++FCP+ CP +SHY +C TC C+ALS C C EGC+CD FL +
Sbjct: 182 GHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNG 241
Query: 1166 GVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEA 1225
C+P+Q CGC HNG Y ++L +C ++C+C + + CQ C PG+VC+
Sbjct: 242 QACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSCKPGQVCQPSGGI 301
Query: 1226 RNC 1228
+C
Sbjct: 302 LSC 304
Score = 32.0 bits (71), Expect = 4.3
Identities = 17/60 (28%), Positives = 33/60 (55%), Gaps = 1/60 (1%)
Query: 1325 LASVSVSRTPDGS-LLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTNDW 1383
LA+ + + GS +++ G++V V V V ++ ++CG CGN++GD +D+
Sbjct: 7 LANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDF 66
>gi|169202626 PREDICTED: similar to mucin 5, partial [Homo sapiens]
Length = 2013
Score = 362 bits (928), Expect = 2e-99
Identities = 328/1207 (27%), Positives = 481/1207 (39%), Gaps = 207/1207 (17%)
Query: 75 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLTPFTVTTKNENRGNPAVSYV 134
C WG HY +FDG F F G CNYV + G + + +++ P +S V
Sbjct: 81 CSTWGSFHYKTFDGDVFRFPGLCNYVFSEH--CGAAYEDFN--IQLRRSQESAAPTLSRV 136
Query: 135 RVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVS 194
+ G I + K G V VNG LP S + + + Q +S + A GL +
Sbjct: 137 ---LMKVDGVVIQLTK---GSVLVNGHPVLLPFSQSG--VLIQQSSSYTKVEARLGLVLM 188
Query: 195 YDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPL 254
++ + + + L + Y CGLCG+ + P ++ + T P+ G+ + DP
Sbjct: 189 WNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLT--PMEFGNLQKMD-DPT 245
Query: 255 CWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMG 314
++C+ P P + G G C L G F+ C A V S+ + C D+C
Sbjct: 246 --EQCQDPVPEPPRNCST---GFGICEELLHGQ--LFSGCVALVDVGSYLEACRQDLCFC 298
Query: 315 GGDHDIL---CKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPS 371
D D+L C LA Y C AG + +DWR C CP N Y C PC +C +
Sbjct: 299 E-DTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSN 357
Query: 372 PAPLTTPAVCEGPCVEGCQCDAGFVLS---ADRCVPLNNGCGCWANGTYHEAGSEFWADG 428
CE CV GC C G VL CVP++ C C NG + G+ + D
Sbjct: 358 QEH---SRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSK-CACVYNGAAYAPGATYSTD- 412
Query: 429 TCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVST-AECQAWGDPHYVTLDG 487
CT +C G+ CQ V C G H+ T DG
Sbjct: 413 ----------------CTNCTCS---------GGRWSCQEVPCPGTCSVLGGAHFSTFDG 447
Query: 488 HRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTLQIYNHSLTLS 546
++ G C Y+L+ PC + FTV G + + + +SVTL + +
Sbjct: 448 KQYTVHGDCSYVLTKPCD-----SSAFTVLAELRRCGLTDSETCLKSVTLSLDGVQTVVV 502
Query: 547 ARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAA-- 604
+ ++ ++ ++ LP ++ S ++ T+ GL L ++L + A
Sbjct: 503 IKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPK 562
Query: 605 YAASLCGLCGNYNQDPADDLKAVGG-----KPAGWQVGGAQGCGECVSKPCPSPCTPEQQ 659
CGLCGN+N ADD + + G A + Q + PC+ +
Sbjct: 563 LRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKTQAACPNIRNSFEDPCSLSVE 622
Query: 660 ESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAAC 719
C ++ DGP CH V P Y+ C+ D C + LC A+++YV AC
Sbjct: 623 NEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNCERSEDCLCAALSSYVHAC 682
Query: 720 QAAGAQLGEWRRPDFCP---LQCPAHSHYELCGDSCPVSCPSLSAPEGCESACR------ 770
A G QLG WR C CP Y +C +C SLS EG + C
Sbjct: 683 AAKGVQLGGWR-DGVCTKPMTTCPKSMTYHYHVSTCQPTCRSLS--EG-DITCSVGFIPV 738
Query: 771 EGCVCDAGFVLSGDT--CVPVGQCGCLHDGRYYPLGE----------------------- 805
+GC+C G L DT CV C C H G P GE
Sbjct: 739 DGCICPKGTFLD-DTGKCVQASNCPCYHRGSMIPNGESVHDSGAICTCTHGKLSCIGGQA 797
Query: 806 ---------VFY------PG-------------------PECERRCEC-------GPGGH 824
VF+ PG P+C C C G GG
Sbjct: 798 PAPVCAAPMVFFDCRNATPGDTGAGCQKSCHTLDMTCYSPQCVPGCVCPDGLVADGEGGC 857
Query: 825 VTCQEGAACGPHEE--------------CRLEDGVQACHATGC-GRCLANGGIHYITLDG 869
+T ++ C +E C + + C C C G HY+T DG
Sbjct: 858 ITAED-CPCVHNEASYRAGQTIRVGCNTCTCDSRMWRCTDDPCLATCAVYGDGHYLTFDG 916
Query: 870 RVYDLHGSCSYVLAQV-CHPKPGDED-FSIVLEKNAAGDL-----QRLLVTVAGQVVSLA 922
+ Y +G C Y L Q C K +D F +V E G + + + + G + L+
Sbjct: 917 QSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTTGTTCSKAIKIFLGGFELKLS 976
Query: 923 QGQ-QVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGR 981
G+ +V E+ +P + ++ G +V+ T GL LL+D + +++ F+GR
Sbjct: 977 HGKVEVIGTDESQEVPYTIRQM-----GIYLVVDTDIGLVLLWDKKTSIFINLSPEFKGR 1031
Query: 982 LCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEGCGPQGCPVCLAEET 1041
+CGLCGNF+ +DF + S V FG +W++ S C + P+ C A
Sbjct: 1032 VCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWKL---SPSCPDALAPK--DPCTANPF 1086
Query: 1042 APYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCA--QKGDKAFLCRSLAAYTA 1099
+ + C L P FA C A + P+ Y+ CV D CA GD C ++AAY
Sbjct: 1087 RKSWAQKQCSILHGP--TFAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAAYAQ 1144
Query: 1100 ACQAAGVAVKPWRTDSFCPLHCPAHS-------HYS----ICTRTC---QGSCAA-LSGL 1144
AC G+ V WRT S CPL C ++ HY C RTC +G C + GL
Sbjct: 1145 ACHEVGLCVS-WRTPSICPLFCDYYNPEGQCEWHYQPCGVPCLRTCRNPRGDCLRDVWGL 1203
Query: 1145 TGCTTRC 1151
GC +C
Sbjct: 1204 EGCYPKC 1210
Score = 288 bits (736), Expect = 3e-77
Identities = 268/1037 (25%), Positives = 389/1037 (37%), Gaps = 197/1037 (18%)
Query: 474 CQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-----SQAV 528
C WG HY T DG F F G C Y+ S C E+F + + S+ +
Sbjct: 81 CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGA---AYEDFNIQLRRSQESAAPTLSRVL 137
Query: 529 SYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLS 588
V +Q+ S+ V+G V LPF +L S + V GL
Sbjct: 138 MKVDGVVIQLTKGSVL----------VNGHPVLLPFSQSGVL-IQQSSSYTKVEARLGLV 186
Query: 589 LAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPA-DDLKAVGGKPAGWQVGGAQGCGECVS 647
L ++ D + L + YA CGLCG++N P +L + K + G Q + +
Sbjct: 187 LMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTPMEFGNLQKMDD-PT 245
Query: 648 KPCPSPCTPEQQESFGGPDACGVISATDGPL-APCHGLVPPAQYFQGCLLDACQVQGHP- 705
+ C P + G C + G L + C LV Y + C D C +
Sbjct: 246 EQCQDPVPEPPRNCSTGFGICEEL--LHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDL 303
Query: 706 -GGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEG 764
+C +A Y C AG +WR PDFCP +CP + Y C C +C +
Sbjct: 304 LSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEHSRA 363
Query: 765 CESACREGCVCDAGFVLS--GDT-CVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGP 821
CE C GC C G VL G T CVPV +C C+++G Y G + +C C C
Sbjct: 364 CEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATY--STDCTN-CTCS- 419
Query: 822 GGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCSYV 881
GG +CQE C G C GG H+ T DG+ Y +HG CSYV
Sbjct: 420 GGRWSCQE-VPCP-------------------GTCSVLGGAHFSTFDGKQYTVHGDCSYV 459
Query: 882 LAQVCHPKPGDEDFSIVLEKNAAG--DLQRLLVTVA------GQVVSLAQGQQVTVDGEA 933
L + C F+++ E G D + L +V VV + +V ++
Sbjct: 460 LTKPCDSSA----FTVLAELRRCGLTDSETCLKSVTLSLDGVQTVVVIKASGEVFLNQIY 515
Query: 934 VALPVAVGRVRVTAEGRNMVL-QTTKGLRLLFD--GDAHLLMSIPSPFRGRLCGLCGNFN 990
LP++ V + ++ QT+ GL+L L M + RG+ CGLCGNFN
Sbjct: 516 TQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFN 575
Query: 991 GNWSDDFVLPNG----SAASSVETFGAAWRVPGSSKGCGEGCGPQGCPVCLAEETAPYES 1046
+DDF +G +AA+ TF P + C L+ E Y +
Sbjct: 576 SIQADDFRTLSGVVEATAAAFFNTFKTQAACPNIRNSFEDPCS-------LSVENEKY-A 627
Query: 1047 NEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGV 1106
C QL + GPF C A + P Y+ C++D C + + LC +L++Y AC A GV
Sbjct: 628 QHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNCERSEDCLCAALSSYVHACAAKGV 687
Query: 1107 AVKPWRTDSFCP---LHCPAHSHYSICTRTCQGSCAALS-GLTGCTTRCF--EGCECDD- 1159
+ WR D C CP Y TCQ +C +LS G C+ +GC C
Sbjct: 688 QLGGWR-DGVCTKPMTTCPKSMTYHYHVSTCQPTCRSLSEGDITCSVGFIPVDGCICPKG 746
Query: 1160 RFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTS--------------------------- 1192
FL G C+ +C C H G +P S+ S
Sbjct: 747 TFLDDTGKCVQASNCPCYHRGSMIPNGESVHDSGAICTCTHGKLSCIGGQAPAPVCAAPM 806
Query: 1193 ---DCSERCSCSSSSG---------LTCQAAGCPPGRVCE-----------VKAEARNC- 1228
DC + +G +TC + C PG VC + AE C
Sbjct: 807 VFFDCRNATPGDTGAGCQKSCHTLDMTCYSPQCVPGCVCPDGLVADGEGGCITAEDCPCV 866
Query: 1229 -------------------------WATR-----GLCVLSVGANLTTFDGARGATTSPGV 1258
W C + + TFDG +
Sbjct: 867 HNEASYRAGQTIRVGCNTCTCDSRMWRCTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCE 926
Query: 1259 YEL-SSRCPGLQNTIPWYRVVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKGV--WVNG 1315
Y L + C G +T +RVV E C G T +K + ++ G
Sbjct: 927 YTLVQNHCGGKDSTQDSFRVVTENVPC----------------GTTGTTCSKAIKIFLGG 970
Query: 1316 LRVDLPAEKLASVSVSRTPDGSLLVRQKA---------GVQVWLGANGKVAVIVSNDHAG 1366
+ L K+ + + + +RQ G+ + + + +S + G
Sbjct: 971 FELKLSHGKVEVIGTDESQEVPYTIRQMGIYLVVDTDIGLVLLWDKKTSIFINLSPEFKG 1030
Query: 1367 KLCGACGNFDGDQTNDW 1383
++CG CGNFD ND+
Sbjct: 1031 RVCGLCGNFDDIAVNDF 1047
Score = 226 bits (576), Expect = 1e-58
Identities = 248/996 (24%), Positives = 382/996 (38%), Gaps = 176/996 (17%)
Query: 6 CGLACSNPQ------IPGTDWVDMEGAAMLYNGQPLKVLLPLLSPDPCHGVTCRPQETCK 59
C C P+ I T V + A +YNG +P + C C
Sbjct: 368 CVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAY-------APGATYSTDCT---NCT 417
Query: 60 EQGGQGVCLP-NYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLTPFT 118
GG+ C TC + G H+ +FDG+++ G C+YVL T C + FT
Sbjct: 418 CSGGRWSCQEVPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVL-TKPC------DSSAFT 470
Query: 119 VTTKNENRG-NPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVA 177
V + G + + ++ VT++ G + G+V +N + T LP+S A+ +++
Sbjct: 471 VLAELRRCGLTDSETCLKSVTLSLDGVQTVVVIKASGEVFLNQIYTQLPISAAN--VTIF 528
Query: 178 QGASKALLV-ADFGLQVSYDW--NWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGT 234
+ ++ ++ GLQ++ ++ + L G CGLCGN + +D +G
Sbjct: 529 RPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGV 588
Query: 235 LAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTC 294
+ + + +++ P + C E+ E+Y +C L GPF C
Sbjct: 589 VEATAAAFFNTFKTQAACPNIRNSFEDPCSLSVEN--EKY-AQHWCSQLT-DADGPFGRC 644
Query: 295 HAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVVIEDWRAQVGCE--ITC 352
HA V P +++ C+ D C D LC AL+SYV AC A GV + WR V + TC
Sbjct: 645 HAAVKPGTYYSNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTC 704
Query: 353 PENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAG-FVLSADRCVPLNNGCGC 411
P++ Y C +C S + V+GC C G F+ +CV +N C C
Sbjct: 705 PKSMTYHYHVSTCQPTCRSLSEGDITCSVGFIPVDGCICPKGTFLDDTGKCVQASN-CPC 763
Query: 412 WANGTYHEAGSEFWADG---TCSQW----------------------CRCGPGGGS---- 442
+ G+ G G TC+ CR G +
Sbjct: 764 YHRGSMIPNGESVHDSGAICTCTHGKLSCIGGQAPAPVCAAPMVFFDCRNATPGDTGAGC 823
Query: 443 --------LVCTPASCGLGEVC--GLLPSGQHGC-------------------------- 466
+ C C G VC GL+ G+ GC
Sbjct: 824 QKSCHTLDMTCYSPQCVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRVGCN 883
Query: 467 ------------QPVSTAECQAWGDPHYVTLDGHRFDFQGTCEY-LLSAPCHGPPLGAEN 513
A C +GD HY+T DG + F G CEY L+ C G ++
Sbjct: 884 TCTCDSRMWRCTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDS 943
Query: 514 FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVA--LPFQLDSLLH 571
F V N G+ + ++++ + + L LS K++V G + +P+ + +
Sbjct: 944 FRVVTENVPCGTTGTTCSKAIKIFLGGFELKLS---HGKVEVIGTDESQEVPYTIRQM-- 998
Query: 572 AHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKP 631
G +VV T GL L +D + + + + + +CGLCGN++ +D
Sbjct: 999 ----GIYLVVDTDIGLVLLWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVNDFATRSRSV 1054
Query: 632 AG--------WQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGP-LAPCH 682
G W++ + C + ++ PCT C ++ GP A CH
Sbjct: 1055 VGDVLEFGNSWKL--SPSCPDALAP--KDPCTANPFRKSWAQKQCSIL---HGPTFAACH 1107
Query: 683 GLVPPAQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCP 740
V PA+Y++ C+ DAC G C AVA Y AC G + WR P CPL C
Sbjct: 1108 AHVEPARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCV-SWRTPSICPLFCD 1166
Query: 741 AHS-------HYELCGDSCPVSCPS--------LSAPEGCESAC-REGCVCDAGFVLSGD 784
++ HY+ CG C +C + + EGC C E + D +
Sbjct: 1167 YYNPEGQCEWHYQPCGVPCLRTCRNPRGDCLRDVWGLEGCYPKCPPEAPIFDEDKMQCVA 1226
Query: 785 TC-VPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAAC-GPHEECRLE 842
TC P C G+ Y G V C+ C C G + AC + R
Sbjct: 1227 TCPTPPLPPRCHVHGKSYRPGAVVPSDKNCQ-SCLCTERGVECTYKAEACVCTYNGQRFH 1285
Query: 843 DGVQACHAT----GC--GRCLANGGIHYITLDGRVY 872
G H T GC RC ANG T++ RVY
Sbjct: 1286 PGDVIYHTTDGTGGCISARCGANG-----TIERRVY 1316
Score = 186 bits (471), Expect = 2e-46
Identities = 153/557 (27%), Positives = 249/557 (44%), Gaps = 61/557 (10%)
Query: 845 VQACHATGCGR-CLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVL---E 900
V+A + GR C G HY T DG V+ G C+YV ++ C EDF+I L +
Sbjct: 69 VRASNPAHNGRVCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGA--AYEDFNIQLRRSQ 126
Query: 901 KNAAGDLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGL 960
++AA L R+L+ V G V+ L +G V V+G V LP + V + ++ GL
Sbjct: 127 ESAAPTLSRVLMKVDGVVIQLTKGS-VLVNGHPVLLPFSQSGVLIQQSSSYTKVEARLGL 185
Query: 961 RLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGS 1020
L+++ D LL+ + + + + CGLCG+FNG +L + + + +E FG ++
Sbjct: 186 VLMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTPME-FGNLQKMDDP 244
Query: 1021 SKGCGEGC--GPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVY 1078
++ C + P+ C C +L + Q F+ C A++ Y C
Sbjct: 245 TEQCQDPVPEPPRNCSTGFG----------ICEELLHGQ-LFSGCVALVDVGSYLEACRQ 293
Query: 1079 DLCAQKGDK--AFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQG 1136
DLC + + +C +LA Y+ C AG + WR FCP CP + Y C C
Sbjct: 294 DLCFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCAD 353
Query: 1137 SCAALSGLTGCTTRCFEGCECDDRFLL---SQGVCIPVQDCGCTHNG-RYLPVNSSLLTS 1192
+C+ C C GC C + +L Q C+PV C C +NG Y P + ++
Sbjct: 354 TCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAP--GATYST 411
Query: 1193 DCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGA 1252
DC+ C+CS +CQ CP G C + GA+ +TFDG +
Sbjct: 412 DCT-NCTCSGGR-WSCQEVPCP------------------GTCSVLGGAHFSTFDGKQYT 451
Query: 1253 TTSPGVYELSSRCPGLQNTIPWYRVVAEVQICH-GKTEAVGQVHIFFQDGMVTLTPNKG- 1310
Y L+ C + V+AE++ C +E + DG+ T+ K
Sbjct: 452 VHGDCSYVLTKPCDSSA-----FTVLAELRRCGLTDSETCLKSVTLSLDGVQTVVVIKAS 506
Query: 1311 --VWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQ--VWLGANGKVAVIVSNDHAG 1366
V++N + LP A+V++ R ++ + G+Q + L ++ + ++ G
Sbjct: 507 GEVFLNQIYTQLPI-SAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRG 565
Query: 1367 KLCGACGNFDGDQTNDW 1383
+ CG CGNF+ Q +D+
Sbjct: 566 QTCGLCGNFNSIQADDF 582
>gi|134031945 SCO-spondin [Homo sapiens]
Length = 5147
Score = 357 bits (916), Expect = 4e-98
Identities = 330/1237 (26%), Positives = 464/1237 (37%), Gaps = 183/1237 (14%)
Query: 73 ATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLTPFTVTTKNENRGNPAVS 132
ATC W HY +FDGR + F G C Y+LA + LTP P
Sbjct: 193 ATCASWSGFHYRTFDGRHYHFLGRCTYLLAGAADSTWAVH-LTP--------GDRCPQPG 243
Query: 133 YVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQ 192
+ + VT+ I + G V V G L S +S+ +L G+
Sbjct: 244 HCQRVTMGPEEVLI-----QAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVV 298
Query: 193 VSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWD 252
V D + +++ G GLCG + P +D + P G LA +G SWR PG +
Sbjct: 299 VRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSE 358
Query: 253 PLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGT-----GGPFTTCHAHVPPESFFKGC 307
C D + P ++ PG A GPF CHA V P + + C
Sbjct: 359 SGCLDAVEVAQGCDPLGLIDADVEPGHLRAEAQDVCHQLLEGPFGQCHAQVSPAEYHEAC 418
Query: 308 VLDVCMGG-------GDHDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEV 360
+ C G G +C ASYV AC + I WR CE CP Y
Sbjct: 419 LFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHIR-WRKPGFCERLCPGGQLYSD 477
Query: 361 CGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEA 420
C CP SC + + C CV GC+C G + CVP + C C+
Sbjct: 478 CVSLCPPSCEAVGQGEEES-CREECVSGCECPRGLFWNGTLCVPAAH-CPCY-------- 527
Query: 421 GSEFWADGTCSQWCRCGPGGG-SLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGD 479
C Q R PG +C P C G H Q + AEC GD
Sbjct: 528 --------YCRQ--RYVPGDTVRQLCNPCVCRDGR--------WHCAQALCPAECAVGGD 569
Query: 480 PHYVTLDGHRFDFQG--TCEYLLSAPCHGPPLGAENFT---VTVANEHRGSQAVSYTRSV 534
HY+T DG + F G C Y L +++ + + EH A S ++
Sbjct: 570 GHYLTFDGRSYSFWGGQGCRYSL----------VQDYVKGQLLILLEHGACDAGSCLHAI 619
Query: 535 TLQIYNHSLTLSARWPRKLQVDGVFVALPF-QLDSLLHAHLSGADVVVTTTSGLSLAFDG 593
++ + + + L R + V+G V LP+ + L S A +++ L
Sbjct: 620 SVSLEDTHIQL--RDSGAVLVNGQDVGLPWIGAEGLSVRRASSAFLLLRWPGAQVLWGLS 677
Query: 594 DSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGK--------PAGWQVGGAQGCGEC 645
D + + +A + GLCG + Q+ DD G + +QV G G C
Sbjct: 678 DPVAYITLDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAGK---GRC 734
Query: 646 VSKPCP--SPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQG 703
S+ SPCT Q AC ++ ++ CH LV ++ CL C
Sbjct: 735 PSEDSALLSPCTTHSQRHAFAEAACAILHSS--VFQECHRLVDKEPFYLRCLAAVCGCDP 792
Query: 704 HPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPE 763
LCP ++ Y C GA WR CP+ CP Y C +C C PE
Sbjct: 793 GSDCLCPVLSAYARRCAQEGAS-PPWRNQTLCPVMCPGGQEYRECAPACGQHC---GKPE 848
Query: 764 GCE--SACREGCVCDAGFVLSGD-TCVPVGQCGCLHDGRYYPLGE--------------- 805
C +C GC C G + + CVP C C R Y G
Sbjct: 849 DCGELGSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRYAPGSATMKECNRCICQERG 908
Query: 806 -------------------VFYPG--------PECERRCECGPGGHVTCQEGAA-----C 833
V+ PG P C G C G C
Sbjct: 909 LWNCTARHCPSQAFCPRELVYAPGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLLDERC 968
Query: 834 GPHEEC-------------RLEDGVQAC-------HATG---CGRCLANGGIHYITLDGR 870
P + C +++ C H TG GRC A+G HY+T DG
Sbjct: 969 VPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGL 1028
Query: 871 VYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVSLAQGQQVTVD 930
+ G+C Y+L + ++ + + L V + G VV + +G+ VTV+
Sbjct: 1029 AFTYPGACEYLLVREASGLFTVSAQNLPCGASGLTCTKALAVRLEGTVVHMLRGRAVTVN 1088
Query: 931 GEAVALP-VAVG-RVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGN 988
G +V P V G + + G ++L T GL LL+DG +L+ + FRGR+ GLCG+
Sbjct: 1089 GVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGD 1148
Query: 989 FNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEGCGPQGCPVCLAEETAPYESNE 1048
F+G+ S+D G + E +WR+ S C E G P + A + +
Sbjct: 1149 FDGDASNDLRSRQGVLEPTAELAAHSWRL---SPLCPEP-GDLPHPCTMNTHRAGW-ARA 1203
Query: 1049 ACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCA--QKGDKAFLCRSLAAYTAACQAAGV 1106
CG L P F C A + P +++ C+YD C GD LC ++A Y C G
Sbjct: 1204 RCGALLQPL--FTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADECARHGH 1261
Query: 1107 AVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGC---TTRCFEGCECDDRFLL 1163
V+ WR+ C L C Y C TC +C G C EGC C + LL
Sbjct: 1262 HVR-WRSQELCSLQCEGGQVYEACGPTCPPTCHEQHPEPGWHCQVVACVEGCFCPEGTLL 1320
Query: 1164 SQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSC 1200
G C+ C C P S+L DC C+C
Sbjct: 1321 HGGACLEPASCPCEWGRNSFP-PGSVLQKDCG-NCTC 1355
Score = 263 bits (673), Expect = 7e-70
Identities = 245/895 (27%), Positives = 342/895 (38%), Gaps = 152/895 (16%)
Query: 73 ATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLTPFTVTTKNENRGNPAVS 132
A C + GD HY +FDGR + F G GC Q + E+ A S
Sbjct: 562 AECAVGGDGHYLTFDGRSYSFWGG-------QGCRYSLVQDYVKGQLLILLEHGACDAGS 614
Query: 133 YVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQ 192
+ ++V+ T+I + + G V VNG LP A+G +SV + +S LL+ G Q
Sbjct: 615 CLHAISVSLEDTHIQLR--DSGAVLVNGQDVGLPWIGAEG-LSVRRASSAFLLLRWPGAQ 671
Query: 193 VSYDWNWRVD-VTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGW 251
V + + V +TL + V GLCG +N +D + P G + SI + ++ G
Sbjct: 672 VLWGLSDPVAYITLDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAG- 730
Query: 252 DPLCWDECRGSCPT--------CPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESF 303
+G CP+ C C L F CH V E F
Sbjct: 731 --------KGRCPSEDSALLSPCTTHSQRHAFAEAACAILHSSV---FQECHRLVDKEPF 779
Query: 304 FKGCVLDVCMGGGDHDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGP 363
+ C+ VC D LC L++Y C G WR Q C + CP Y C P
Sbjct: 780 YLRCLAAVCGCDPGSDCLCPVLSAYARRCAQEGAS-PPWRNQTLCPVMCPGGQEYRECAP 838
Query: 364 PCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSAD-RCVPLN---------------- 406
C C P G CV GC C G + + +CVP +
Sbjct: 839 ACGQHCGKPEDCGEL----GSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRYAPGSA 894
Query: 407 -----NGCGCWANGTY-----HEAGSEF------WADGTCSQWC-------RCGPGG-GS 442
N C C G + H F +A G C C C G
Sbjct: 895 TMKECNRCICQERGLWNCTARHCPSQAFCPRELVYAPGACLLTCDSPSANHSCPAGSTDG 954
Query: 443 LVCTPASCGLGEVC---GLLP---SGQ----------------------HGCQPVSTAEC 474
VC P + L E C L P SGQ H + C
Sbjct: 955 CVCPPGTVLLDERCVPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRC 1014
Query: 475 QAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSV 534
QA G PHYVT DG F + G CEYLL G FTV+ N G+ ++ T+++
Sbjct: 1015 QASGAPHYVTFDGLAFTYPGACEYLLVREASG------LFTVSAQNLPCGASGLTCTKAL 1068
Query: 535 TLQIYNHSLTLSARWPRKLQVDGVFVALP-FQLDSLLHAHLSGADVVVTTTSGLSLAFDG 593
+++ + R + V+GV V P L +G ++++T GL+L +DG
Sbjct: 1069 AVRL--EGTVVHMLRGRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDG 1126
Query: 594 DSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGG--KPAGWQVGGAQGCGECVSKP-- 649
+ V +++ + + GLCG+++ D ++DL++ G +P + +P
Sbjct: 1127 GTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLSPLCPEPGD 1186
Query: 650 CPSPCTPEQQESFGGPDACGVISATDGPL-APCHGLVPPAQYFQGCLLDACQVQ--GHPG 706
P PCT + CG + PL CH VPP Q+++ CL DAC G
Sbjct: 1187 LPHPCTMNTHRAGWARARCGALLQ---PLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCE 1243
Query: 707 GLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEG-- 764
LC A+ATY C G + WR + C LQC YE CG +CP +C G
Sbjct: 1244 CLCSAIATYADECARHGHHV-RWRSQELCSLQCEGGQVYEACGPTCPPTCHEQHPEPGWH 1302
Query: 765 CE-SACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFY--------------- 808
C+ AC EGC C G +L G C+ C C +P G V
Sbjct: 1303 CQVVACVEGCFCPEGTLLHGGACLEPASCPCEWGRNSFPPGSVLQKDCGNCTCQEGQWHC 1362
Query: 809 --PGPECERRCECGPGGHVTCQEGAACGPH-------EECRLEDGVQACHATGCG 854
G CE G CQE C PH ++C + C A GCG
Sbjct: 1363 GGDGGHCEELVPACAEGEALCQENGHCVPHGWLCDNQDDCGDGSDEEGCAAPGCG 1417
Score = 246 bits (628), Expect = 1e-64
Identities = 297/1212 (24%), Positives = 427/1212 (35%), Gaps = 225/1212 (18%)
Query: 341 DWRAQVGCEITCPENSHYEVCGPPCPASCPS-PAPLTTPAVCEG------PCVEGCQCDA 393
D +++G + P + + P P CP P T PA P G C
Sbjct: 46 DHYSRLGWRLDLPWSGRSGLTRSPAPGLCPIYKPPETRPAKWNRTVRTCCPGWGGAHCTE 105
Query: 394 GFVLSADR--CVPLNNGCGCWANGTYHEAGS----------EFWADGTCSQWCR-CG--- 437
++ C + C A AGS + W DG+ SQ CR C
Sbjct: 106 ALAKASPEGHCFAMWQ-CQLQAGSANASAGSLEECCARPWGQSWWDGS-SQACRSCSSRH 163
Query: 438 -PGGGS--LVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQG 494
PG S + P + +G++ QH +P +T C +W HY T DG + F G
Sbjct: 164 LPGSASSPALLQPLAGAVGQLWS-----QHQ-RPSAT--CASWSGFHYRTFDGRHYHFLG 215
Query: 495 TCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQ 554
C YLL+ + V + R Q + + VT+ P ++
Sbjct: 216 RCTYLLAGAAD------STWAVHLTPGDRCPQP-GHCQRVTM------------GPEEVL 256
Query: 555 VDGVFVALPFQL-----DSLLHA---HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYA 606
+ V++ QL LLH G +V++ G+ + D + + V
Sbjct: 257 IQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDRTGSISISVDHELW 316
Query: 607 ASLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQ-GCGEC--VSKPCPSPCT 655
GLCG YN P DD GG A W++ G++ GC + V++ C
Sbjct: 317 GQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSESGCLDAVEVAQGCDPLGL 376
Query: 656 PEQQESFG-----GPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQ-------VQG 703
+ G D C + +GP CH V PA+Y + CL C +G
Sbjct: 377 IDADVEPGHLRAEAQDVCHQL--LEGPFGQCHAQVSPAEYHEACLFAYCAGAMAGSGQEG 434
Query: 704 HPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSL--SA 761
+C A+YV AC + WR+P FC CP Y C CP SC ++
Sbjct: 435 RQQAVCATFASYVQACARRHIHI-RWRKPGFCERLCPGGQLYSDCVSLCPPSCEAVGQGE 493
Query: 762 PEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGP 821
E C C GC C G +G CVP C C Y + + PG + C
Sbjct: 494 EESCREECVSGCECPRGLFWNGTLCVPAAHCPC------YYCRQRYVPGDTVRQLC---- 543
Query: 822 GGHVTCQEGAACGPHEECRLEDGVQACHATGC-GRCLANGGIHYITLDGRVYDLHG--SC 878
C DG C C C G HY+T DGR Y G C
Sbjct: 544 ---------------NPCVCRDGRWHCAQALCPAECAVGGDGHYLTFDGRSYSFWGGQGC 588
Query: 879 SYVLAQVCHPKPGDEDFSIVLEKNA--AGD-LQRLLVTVAGQVVSLAQGQQVTVDGEAVA 935
Y L Q I+LE A AG L + V++ + L V V+G+ V
Sbjct: 589 RYSLVQ----DYVKGQLLILLEHGACDAGSCLHAISVSLEDTHIQLRDSGAVLVNGQDVG 644
Query: 936 LP-VAVGRVRVTAEGRNMVLQTTKGLRLLFD-GDAHLLMSIPSPFRGRLCGLCGNFNGNW 993
LP + + V +L G ++L+ D +++ ++ GLCG F N
Sbjct: 645 LPWIGAEGLSVRRASSAFLLLRWPGAQVLWGLSDPVAYITLDPRHAHQVQGLCGTFTQNQ 704
Query: 994 SDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQL 1053
DDF+ P G +S+ F + ++V G + E C + AC L
Sbjct: 705 QDDFLTPAGDVETSIAAFASKFQVAGKGRCPSEDSAL--LSPCTTHSQRHAFAEAACAIL 762
Query: 1054 RNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRT 1113
+ F C ++ ++ +C+ +C LC L+AY C G A PWR
Sbjct: 763 HS--SVFQECHRLVDKEPFYLRCLAAVCGCDPGSDCLCPVLSAYARRCAQEG-ASPPWRN 819
Query: 1114 DSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLS-QGVCIPVQ 1172
+ CP+ CP Y C C C G C GC C L +G C+P
Sbjct: 820 QTLCPVMCPGGQEYRECAPACGQHCGKPED-CGELGSCVAGCNCPLGLLWDPEGQCVPPS 878
Query: 1173 DCGCTHNG-RYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWAT 1231
C C RY P ++++ +C+ RC C C A CP C R
Sbjct: 879 LCPCQLGARRYAPGSATM--KECN-RCICQERGLWNCTARHCPSQAFC-----PRELVYA 930
Query: 1232 RGLCVL---SVGANLTTFDGAR-GATTSPGVYELSSRC--PGL---QNTIPWYRVVAEVQ 1282
G C+L S AN + G+ G PG L RC P L +++ WY A +Q
Sbjct: 931 PGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLLDERCVPPDLCPCRHSGQWYLPNATIQ 990
Query: 1283 ------ICH------------GKTEAVGQVHIFFQDGMVTLTP----------------- 1307
+C G+ +A G H DG+ P
Sbjct: 991 EDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREASGLFTV 1050
Query: 1308 -------------------------------NKGVWVNGLRVDLPAEKLASVSVSRTPDG 1336
+ V VNG+ V P R
Sbjct: 1051 SAQNLPCGASGLTCTKALAVRLEGTVVHMLRGRAVTVNGVSVTPPKVYTGPGLSLRRAGL 1110
Query: 1337 SLLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHDSQ------EKP 1390
LL+ G+ + +V V +S G++ G CG+FDGD +ND Q +
Sbjct: 1111 FLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAEL 1170
Query: 1391 AMEKWRAQDFSP 1402
A WR P
Sbjct: 1171 AAHSWRLSPLCP 1182
Score = 164 bits (414), Expect = 7e-40
Identities = 130/420 (30%), Positives = 177/420 (42%), Gaps = 40/420 (9%)
Query: 45 DPCHGVTCRPQET-CKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLAT 103
+ C+ CR ++ C Q G C + G PHY +FDG F + G C Y+L
Sbjct: 991 EDCNVCVCRGRQWHCTGQRRSGRCQAS--------GAPHYVTFDGLAFTYPGACEYLLVR 1042
Query: 104 TGCLGVSTQGLTPFTVTTKNENRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLT 163
GL FTV+ +N G ++ + + V GT + + + V VNGV
Sbjct: 1043 ------EASGL--FTVSAQNLPCGASGLTCTKALAVRLEGTVVHMLRGRA--VTVNGVSV 1092
Query: 164 ALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRN 223
P +S+ + LL GL + +D RV V L + G V GLCG+ D +
Sbjct: 1093 TPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGD 1152
Query: 224 PNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCP-TCPEDRLEQYEGPGFCGP 282
+ND G L P+ + SWR PLC + G P C + CG
Sbjct: 1153 ASNDLRSRQGVLEPTAELAAHSWRL---SPLCPEP--GDLPHPCTMNTHRAGWARARCGA 1207
Query: 283 LAPGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDHDILCKALASYVAACQAAGVVIE 340
L FT CHA VPP+ ++ C+ D C GGD + LC A+A+Y C G +
Sbjct: 1208 LLQPL---FTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADECARHGHHVR 1264
Query: 341 DWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSAD 400
WR+Q C + C YE CGP CP +C P CVEGC C G +L
Sbjct: 1265 -WRSQELCSLQCEGGQVYEACGPTCPPTCHEQHPEPGWHCQVVACVEGCFCPEGTLLHGG 1323
Query: 401 RCVPLNNGCGC-WANGTYHEAGSEFWAD-GTCS----QWCRCGPGGGSLVCTPASCGLGE 454
C+ C C W ++ GS D G C+ QW CG GG +C GE
Sbjct: 1324 ACLE-PASCPCEWGRNSF-PPGSVLQKDCGNCTCQEGQW-HCGGDGGHCEELVPACAEGE 1380
Score = 69.7 bits (169), Expect = 2e-11
Identities = 41/123 (33%), Positives = 48/123 (39%), Gaps = 13/123 (10%)
Query: 736 PLQCPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCL 795
P CP + C P SC LSAP G C GC C +G +L + CVP C C
Sbjct: 3087 PGMCPRDKQWLDCAQG-PASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCA 3145
Query: 796 HDGRYYPLGEVFYPGPECERRCECGPG-----GHVTCQEG----AACGPHEECRLEDGVQ 846
H+G YP G CE C C G C EG + P +C G
Sbjct: 3146 HEGHLYPPGSTVV--RPCE-NCSCVSGLIANCSSWPCAEGEPTWSPWTPWSQCSASCGPA 3202
Query: 847 ACH 849
CH
Sbjct: 3203 RCH 3205
Score = 67.0 bits (162), Expect = 1e-10
Identities = 35/99 (35%), Positives = 42/99 (42%), Gaps = 3/99 (3%)
Query: 1118 PLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQDCGCT 1177
P CP + C + SCA LS G C GC C LL VC+P QDC C
Sbjct: 3087 PGMCPRDKQWLDCAQG-PASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCA 3145
Query: 1178 HNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPG 1216
H G P S+++ E CSC S C + C G
Sbjct: 3146 HEGHLYPPGSTVVRP--CENCSCVSGLIANCSSWPCAEG 3182
Score = 63.5 bits (153), Expect = 1e-09
Identities = 65/212 (30%), Positives = 77/212 (36%), Gaps = 56/212 (26%)
Query: 244 GSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESF 303
G+W W+ W C SC + R P P GG A P S
Sbjct: 2556 GAWAM--WE--AWGPCSVSCGGGHQSRQRSCVDP------PPKNGG------APCPGASQ 2599
Query: 304 FKG-CVLDVCMGGGDHDILCKALASYVAA--CQAAGVVIEDWRAQVGCEITCPENSHYEV 360
+ C L C GG D C+ YV+A CQ V
Sbjct: 2600 ERAPCGLQPCSGGTD----CELGRVYVSADLCQKGLV----------------------- 2632
Query: 361 CGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEA 420
PPCP SC P + C G CVEGC+C G +L RC+PL+ C C
Sbjct: 2633 --PPCPPSCLDPKANRS---CSGHCVEGCRCPPGLLLHDTRCLPLSE-CPCLVGEELKWP 2686
Query: 421 GSEFWADGTCSQWCRCGPGGGSLVCTPASCGL 452
G F G CSQ C C G L+C P C L
Sbjct: 2687 GVSFLL-GNCSQ-CVCEK--GELLCQPGGCPL 2714
Score = 60.1 bits (144), Expect = 1e-08
Identities = 65/227 (28%), Positives = 83/227 (36%), Gaps = 40/227 (17%)
Query: 248 APGWDPLCWDECRGSCPT-----CPEDRLEQYE-GPGFCG-PLAPGTGGPFTTCHAHVPP 300
APG P W CP+ CP D ++ P C P G P++TC A
Sbjct: 2790 APGGGP-GWRSRSRLCPSPGDSSCPGDATQEEPCSPPVCPVPSIWGLWAPWSTCSAP--- 2845
Query: 301 ESFFKGCVLDVCMGG-GDHDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHY- 358
C GG C +LA C D Q C CPEN +
Sbjct: 2846 -----------CDGGIQTRGRSCSSLAPGDTTCPGPHSQTRDCNTQP-CTAQCPENMLFR 2893
Query: 359 --EVC---GPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWA 413
E C G PCP C + P C G C GC C G L C+P + C C
Sbjct: 2894 SAEQCHQEGGPCPRLCLTQGP---GIECTGFCAPGCTCPPGLFLHNASCLP-RSQCPCQL 2949
Query: 414 NGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLP 460
+G + +G+ D +C+ C C G + CT C + CG P
Sbjct: 2950 HGQLYASGAMARLD-SCNN-CTC--VSGKMACTSERCPV--ACGWSP 2990
Score = 55.8 bits (133), Expect = 3e-07
Identities = 66/241 (27%), Positives = 81/241 (33%), Gaps = 44/241 (18%)
Query: 242 WGGSWRAPGWDPLC-WDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVP- 299
W + P W P W +C SC R ++ P T P P
Sbjct: 3177 WPCAEGEPTWSPWTPWSQCSASCGPA---RCHRHRFCARSPSAVPSTVAPLPLPATPTPL 3233
Query: 300 ---PESFFKGCVLDVCMGGGDHDIL-----CK-----ALASYVAAC-----QAAGVVIED 341
PE+ + C+L C G C L S AC Q G E
Sbjct: 3234 CSGPEAEEEPCLLQGCDRAGGWGPWGPWSHCSRSCGGGLRSRTRACDQPPPQGLGDYCEG 3293
Query: 342 WRAQ--VGCEITCP-------ENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCD 392
RAQ V + CP E + Y CGPPCP SC C C GC C
Sbjct: 3294 PRAQGEVCQALPCPVTNCTAIEGAEYSPCGPPCPRSCDDLVH------CVWRCQPGCYCP 3347
Query: 393 AGFVLSADRCVPLNNG-CGC--WANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPAS 449
G VLS++ + + G C C G H G+ C+ C C G L CT
Sbjct: 3348 PGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGCNH-CTCLE--GRLNCTDLP 3404
Query: 450 C 450
C
Sbjct: 3405 C 3405
Score = 55.1 bits (131), Expect = 5e-07
Identities = 65/257 (25%), Positives = 90/257 (35%), Gaps = 33/257 (12%)
Query: 212 AVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWG---GSWRAPGWDPLCWDECRGSCPTCPE 268
A C + + P N P+ T P P G G+ W P W+ C SC +
Sbjct: 3913 ANCTMGDPLQERPCN---LPSCTELPVCPGPGCGAGNCSWTSWAP--WEPCSRSCGVGQQ 3967
Query: 269 DRLEQYEGPGFCGPLAPG-----TGGPFTTCHAHVPPESFFKGCVLDVC--MGGGDHDIL 321
RL Y PG G P F A P + + C GG +
Sbjct: 3968 RRLRAYRPPGPGGHWCPNILTAYQERRFCNLRACPVPGGWSRWSPWSWCDRSCGGGQSLR 4027
Query: 322 CKALASYVAACQAAGVVIEDWRAQ----VGCEITCPENSHYEVCGPPCPASCPSPAPLTT 377
++ +S + A E +A+ + CE CP C CP C + L
Sbjct: 4028 SRSCSSPPSKNGGAPCAGERHQARLCNPMPCEAGCPAGMEVVTCANRCPRRC---SDLQE 4084
Query: 378 PAVCEGP--CVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWC- 434
VC+ C +GC+C G + CVP+ + C C +A WA G+ Q
Sbjct: 4085 GIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGH-CDC------TDAQGHSWAPGSQHQDAC 4137
Query: 435 -RCGPGGGSLVCTPASC 450
C G L CT C
Sbjct: 4138 NNCSCQAGQLSCTAQPC 4154
Score = 54.7 bits (130), Expect = 6e-07
Identities = 68/233 (29%), Positives = 81/233 (34%), Gaps = 57/233 (24%)
Query: 645 CVSKPCP------SPCTPEQQESFG-GPDAC----------GVISATDGPL----APCHG 683
C S PC SP TP Q S GP C + +T PL P
Sbjct: 3174 CSSWPCAEGEPTWSPWTPWSQCSASCGPARCHRHRFCARSPSAVPSTVAPLPLPATPTPL 3233
Query: 684 LVPPAQYFQGCLLDACQVQGHPGGLCP----------AVATYVAACQAAGAQ-LGEW--- 729
P + CLL C G G P + + AC Q LG++
Sbjct: 3234 CSGPEAEEEPCLLQGCDRAGGWGPWGPWSHCSRSCGGGLRSRTRACDQPPPQGLGDYCEG 3293
Query: 730 --RRPDFCP-LQCPAHS-------HYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGF 779
+ + C L CP + Y CG CP SC L C C+ GC C G
Sbjct: 3294 PRAQGEVCQALPCPVTNCTAIEGAEYSPCGPPCPRSCDDLVH---CVWRCQPGCYCPPGQ 3350
Query: 780 VLS--GDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEG 830
VLS G CV G C CL G+ +PG R C H TC EG
Sbjct: 3351 VLSSNGAICVQPGHCSCLD----LLTGQRHHPGARLARPDGC---NHCTCLEG 3396
Score = 54.3 bits (129), Expect = 8e-07
Identities = 37/126 (29%), Positives = 47/126 (37%), Gaps = 9/126 (7%)
Query: 1117 CPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTR--CFEGCECDDRFLLSQGVCIPVQDC 1174
C CPA C C C+ L C C +GC C L G C+P+ C
Sbjct: 4058 CEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGHC 4117
Query: 1175 GCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATRGL 1234
CT + S C+ CSC + L+C A CPP C A + W+
Sbjct: 4118 DCTDAQGHSWAPGSQHQDACN-NCSCQAGQ-LSCTAQPCPPPTHC-----AWSHWSAWSP 4170
Query: 1235 CVLSVG 1240
C S G
Sbjct: 4171 CSHSCG 4176
Score = 53.9 bits (128), Expect = 1e-06
Identities = 61/243 (25%), Positives = 80/243 (32%), Gaps = 33/243 (13%)
Query: 626 AVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLV 685
A GG P GW+ ++ C CP T E+ S P C P+ GL
Sbjct: 2790 APGGGP-GWR-SRSRLCPSPGDSSCPGDATQEEPCS---PPVC--------PVPSIWGLW 2836
Query: 686 PPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHY 745
P Q +G C ++A C +Q + C QCP + +
Sbjct: 2837 APWSTCSAPCDGGIQTRGRS---CSSLAPGDTTCPGPHSQTRDCNTQP-CTAQCPENMLF 2892
Query: 746 ---ELC---GDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGR 799
E C G CP C + C C GC C G L +C+P QC C G+
Sbjct: 2893 RSAEQCHQEGGPCPRLCLTQGPGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQ 2952
Query: 800 YYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLAN 859
Y G + R C + TC G E C + G C N
Sbjct: 2953 LYASGAM-------ARLDSC---NNCTCVSGKMACTSERCPVACGWSPWTLWSLCSCSCN 3002
Query: 860 GGI 862
GI
Sbjct: 3003 VGI 3005
Score = 53.5 bits (127), Expect = 1e-06
Identities = 59/224 (26%), Positives = 77/224 (34%), Gaps = 40/224 (17%)
Query: 632 AGWQVGGAQGCG-ECVSKPC--PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPA 688
A W++ AQ +C + C S P Q+ GP SA APC G
Sbjct: 4732 ASWELAPAQAVQLDCQNCTCVNESLVCPHQECPVLGP-----WSAWSSCSAPCGG----- 4781
Query: 689 QYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELC 748
G + +G PG VA CQA + + CP +CP C
Sbjct: 4782 ----GTMERHRTCEGGPG---------VAPCQAQDTEQRQECNLQPCP-ECPPGQVLSAC 4827
Query: 749 GDSCPVSCPSLSAPEGC-ESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPL---- 803
SCP C L C + C+ GC C G +L TCVP C C + L
Sbjct: 4828 ATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTACPCTQHSLPWGLTLTL 4887
Query: 804 ---GEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDG 844
+ PG R C C GA +C++ G
Sbjct: 4888 EEQAQELPPGTVLTRNCT-----RCVCHGGAFSCSLVDCQVPPG 4926
Score = 52.8 bits (125), Expect = 2e-06
Identities = 27/81 (33%), Positives = 33/81 (40%), Gaps = 2/81 (2%)
Query: 1134 CQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSD 1193
C SC C+ C EGC C LL C+P+ +C C S L +
Sbjct: 2635 CPPSCLDPKANRSCSGHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLGN 2694
Query: 1194 CSERCSCSSSSGLTCQAAGCP 1214
CS+ C C L CQ GCP
Sbjct: 2695 CSQ-CVCEKGE-LLCQPGGCP 2713
Score = 52.8 bits (125), Expect = 2e-06
Identities = 58/233 (24%), Positives = 75/233 (32%), Gaps = 55/233 (23%)
Query: 652 SPCTPE--------QQESFGGPDACGVISATD--GPLAPCHGLVPPAQYFQGCLLDACQV 701
+PCT E Q+E+ C V A GP +PC + + + C
Sbjct: 3445 APCTGEAGEAGAQHQREACPSYATCPVDGAWGPWGPWSPCDMCLGQSHRSRACSRPPTPE 3504
Query: 702 QGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSA 761
G P CP T CQ Q + C CG CP SC LS
Sbjct: 3505 GGRP---CPGNHTQSRPCQENSTQCTD----------CGGGQSLHPCGQPCPRSCQDLSP 3551
Query: 762 PEGCESA---CREGCVCDAGFVLSGDTCVPVGQCGCLHD--------------GRYYPLG 804
C+ C+ C C G + CVP C C + G +
Sbjct: 3552 GSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRCQYQPGAMGIPENQSRSAGSRFSSW 3611
Query: 805 EVFYPGP----ECERRCECGPGGHVTCQEGAAC---------GPHEECRLEDG 844
E PG C+ C C G + CQE C GP E+C + G
Sbjct: 3612 ESLEPGEVVTGPCD-NCTC-VAGILQCQEVPDCPDPGVWSSWGPWEDCSVSCG 3662
Score = 51.6 bits (122), Expect = 5e-06
Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 12/110 (10%)
Query: 735 CPLQCPAHSHYELCGDSCPVSCPSLSAPEGCES--ACREGCVCDAGFVLSGDTCVPVGQC 792
C CPA C + CP C L C+ C++GC C G + CVP+G C
Sbjct: 4058 CEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGHC 4117
Query: 793 GCLHDGRYYPLGEVFYPGPECE---RRCECGPGGHVTCQEGAACGPHEEC 839
C G + PG + + C C G ++C C P C
Sbjct: 4118 DCTD-----AQGHSWAPGSQHQDACNNCSC-QAGQLSC-TAQPCPPPTHC 4160
Score = 50.4 bits (119), Expect = 1e-05
Identities = 41/133 (30%), Positives = 50/133 (37%), Gaps = 6/133 (4%)
Query: 365 CPASCPSPAPLTTPAVCEGPCVEGCQCDAG-FVLSADRCVPLNNGCGCWANGTYHEAGSE 423
C +C T + C GC C G F A CVP ++ C CW G H GSE
Sbjct: 4940 CEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDH-CECWHLGRPHLPGSE 4998
Query: 424 FWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYV 483
W + S C G + C+P +C GE L P C P E P
Sbjct: 4999 -WQEACESCLCLSGRPVCTQHCSPLTCAQGEEMVLEPG---SCCPSCRREAPEEQSPSCQ 5054
Query: 484 TLDGHRFDFQGTC 496
L R +GTC
Sbjct: 5055 LLTELRNFTKGTC 5067
Score = 48.5 bits (114), Expect = 4e-05
Identities = 27/77 (35%), Positives = 32/77 (41%), Gaps = 5/77 (6%)
Query: 752 CPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGP 811
CP SC A C C EGC C G +L C+P+ +C CL G F G
Sbjct: 2635 CPPSCLDPKANRSCSGHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLGN 2694
Query: 812 ECERRCE-----CGPGG 823
+ CE C PGG
Sbjct: 2695 CSQCVCEKGELLCQPGG 2711
Score = 47.4 bits (111), Expect = 1e-04
Identities = 34/130 (26%), Positives = 47/130 (36%), Gaps = 9/130 (6%)
Query: 1091 CRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQ--GSCAALSGLTG-- 1146
C SLA C + T C CP + + + Q G C L G
Sbjct: 2857 CSSLAPGDTTCPGPHSQTRDCNTQP-CTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPG 2915
Query: 1147 --CTTRCFEGCECDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSS 1204
CT C GC C L C+P C C +G+ L + ++ D C+C S
Sbjct: 2916 IECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQ-LYASGAMARLDSCNNCTCVSGK 2974
Query: 1205 GLTCQAAGCP 1214
+ C + CP
Sbjct: 2975 -MACTSERCP 2983
Score = 47.0 bits (110), Expect = 1e-04
Identities = 36/126 (28%), Positives = 48/126 (38%), Gaps = 13/126 (10%)
Query: 1099 AACQAAGVAVKPWRTDSF----CPLHCPAHSHYSI--CTRTCQGSCAALSGLTGCTTR-C 1151
A G +PW +S CP C A C C SCA L C C
Sbjct: 4642 AEALCGGGCREPWAQESCNGGPCP-ECEAQDTVFTLDCANQCPHSCADLWDRVQCLQGPC 4700
Query: 1152 FEGCECDDRFLLSQGVCIPVQDCGC---THNGRYLPVNSSLLTSDCSERCSCSSSSGLTC 1208
GC C L+ G C+P+ C C + N + + + DC + C+C + S L C
Sbjct: 4701 RPGCRCPPGQLVQDGRCVPISSCRCGLPSANASWELAPAQAVQLDC-QNCTCVNES-LVC 4758
Query: 1209 QAAGCP 1214
CP
Sbjct: 4759 PHQECP 4764
Score = 46.6 bits (109), Expect = 2e-04
Identities = 49/194 (25%), Positives = 65/194 (33%), Gaps = 31/194 (15%)
Query: 1099 AACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTR-CFEGCEC 1157
A CQA + CP CP S C +C C L C C GC C
Sbjct: 4797 APCQAQDTEQRQECNLQPCP-ECPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGC 4855
Query: 1158 DDRFLLSQGVCIPVQDCGCTHN-------------GRYLPVNSSLLTSDCSERCSCSSSS 1204
LL G C+P C CT + + LP ++LT +C+ RC C +
Sbjct: 4856 PGGQLLHNGTCVPPTACPCTQHSLPWGLTLTLEEQAQELP-PGTVLTRNCT-RCVCHGGA 4913
Query: 1205 GLTCQAAGC--PPGR-----------VCEVKAEARNCWATRGLCVLSVGANLTTFDGARG 1251
+C C PPG +CE N T+ C + + G
Sbjct: 4914 -FSCSLVDCQVPPGETWQQVAPGELGLCEQTCLEMNATKTQSNCSSARASGCVCQPGHFR 4972
Query: 1252 ATTSPGVYELSSRC 1265
+ P V E C
Sbjct: 4973 SQAGPCVPEDHCEC 4986
Score = 45.8 bits (107), Expect = 3e-04
Identities = 35/102 (34%), Positives = 41/102 (40%), Gaps = 15/102 (14%)
Query: 752 CPVSCPSLSAPE---GCESACREGCVCDAG-FVLSGDTCVPVGQCGCLHDGRYYPLGEVF 807
C +C ++A + C SA GCVC G F CVP C C H LG
Sbjct: 4940 CEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDHCECWH------LGRPH 4993
Query: 808 YPGPECERRCE---CGPGGHVTCQEGA--ACGPHEECRLEDG 844
PG E + CE C G V Q + C EE LE G
Sbjct: 4994 LPGSEWQEACESCLCLSGRPVCTQHCSPLTCAQGEEMVLEPG 5035
Score = 45.4 bits (106), Expect = 4e-04
Identities = 34/115 (29%), Positives = 44/115 (38%), Gaps = 13/115 (11%)
Query: 349 EITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEG--PCVEGCQCDAGFVLSADRCVPLN 406
E +C + CG PC C A + +C+ PC GC C G + A C+P
Sbjct: 4420 EDSCTPPFEFHACGSPCAGLC---ATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIPPE 4476
Query: 407 NGCGCWANGTYHEAGSEFWADGTCSQWCR-CGPGGGSLVCTPASCGLGEVCGLLP 460
C CW + + AG C+ C G L CT C GLLP
Sbjct: 4477 E-CNCW-HTSAAGAGMTLAPGDRLQLGCKECECRRGELHCTSQGCQ-----GLLP 4524
Score = 45.1 bits (105), Expect = 5e-04
Identities = 51/222 (22%), Positives = 68/222 (30%), Gaps = 73/222 (32%)
Query: 645 CVSKPCPSPCT---------------PEQQESFGGPDACGVISATDGPLAPCHGLVPPAQ 689
C S PCP C +Q+ GP + G + APC L
Sbjct: 4357 CYSGPCPEECVWSSWSSWTRCSCRVLVQQRYRHQGPASRGARAG-----APCTRL---DG 4408
Query: 690 YFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCG 749
+F+ CL+ C P + AG C H ++LC
Sbjct: 4409 HFRPCLISNCS----EDSCTPPFEFHACGSPCAGL--------------CATHLSHQLCQ 4450
Query: 750 DSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYP 809
D P C+ GC C G + C+P +C C H G P
Sbjct: 4451 DLPP---------------CQPGCYCPKGLLEQAGGCIPPEECNCWHTSA-AGAGMTLAP 4494
Query: 810 GPECE---RRCECGPGG-HVTCQ------------EGAACGP 835
G + + CEC G H T Q E + CGP
Sbjct: 4495 GDRLQLGCKECECRRGELHCTSQGCQGLLPLSEWSEWSPCGP 4536
Score = 45.1 bits (105), Expect = 5e-04
Identities = 42/152 (27%), Positives = 56/152 (36%), Gaps = 24/152 (15%)
Query: 329 VAACQAAGVVIEDWRAQVGCEIT----CPENSHYEVCGPPCPASCPSPAPLTTPAVC-EG 383
VA CQA +D + C + CP C CP C P A+C +
Sbjct: 4796 VAPCQA-----QDTEQRQECNLQPCPECPPGQVLSACATSCPCLCWHLQP---GAICVQE 4847
Query: 384 PCVEGCQCDAGFVLSADRCVPLNNGCGCWANG-------TYHEAGSEFWADGTCSQWC-R 435
PC GC C G +L CVP C C + T E E ++ C R
Sbjct: 4848 PCQPGCGCPGGQLLHNGTCVP-PTACPCTQHSLPWGLTLTLEEQAQELPPGTVLTRNCTR 4906
Query: 436 CGPGGGSLVCTPASCGL--GEVCGLLPSGQHG 465
C GG+ C+ C + GE + G+ G
Sbjct: 4907 CVCHGGAFSCSLVDCQVPPGETWQQVAPGELG 4938
Score = 44.7 bits (104), Expect = 6e-04
Identities = 27/96 (28%), Positives = 38/96 (39%), Gaps = 14/96 (14%)
Query: 748 CGDSCPVSCPSLSAPEGC-ESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEV 806
C + CP SC L C + CR GC C G ++ CVP+ C C P
Sbjct: 4678 CANQCPHSCADLWDRVQCLQGPCRPGCRCPPGQLVQDGRCVPISSCRC-----GLPSANA 4732
Query: 807 FY---PGPECERRCECGPGGHVTCQEGAACGPHEEC 839
+ P + C+ + TC + PH+EC
Sbjct: 4733 SWELAPAQAVQLDCQ-----NCTCVNESLVCPHQEC 4763
Score = 44.3 bits (103), Expect = 8e-04
Identities = 41/121 (33%), Positives = 53/121 (43%), Gaps = 19/121 (15%)
Query: 340 EDWRAQVGCEI-TCPENSHYEV-----CGPPCPASCPSPAPLTTPAVC-EGPCVEGCQCD 392
E W AQ C CPE + C CP SC A L C +GPC GC+C
Sbjct: 4652 EPW-AQESCNGGPCPECEAQDTVFTLDCANQCPHSC---ADLWDRVQCLQGPCRPGCRCP 4707
Query: 393 AGFVLSADRCVPLNNGCGCW---ANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPAS 449
G ++ RCVP+++ C C AN ++ A ++ A Q C C SLVC
Sbjct: 4708 PGQLVQDGRCVPISS-CRCGLPSANASWELAPAQ--AVQLDCQNCTC--VNESLVCPHQE 4762
Query: 450 C 450
C
Sbjct: 4763 C 4763
Score = 43.9 bits (102), Expect = 0.001
Identities = 147/647 (22%), Positives = 199/647 (30%), Gaps = 152/647 (23%)
Query: 645 CVSKPCPSP----CTPEQQ--ESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLL-- 696
C +PC P C ++Q + GP +C +SA G CH P G LL
Sbjct: 3077 CGLQPCAGPVPGMCPRDKQWLDCAQGPASCAELSAPRGTNQTCH---PGCHCPSGMLLLN 3133
Query: 697 --------DACQVQGH---PGGL-------CPAVATYVAACQAAGAQLGE-----WRRPD 733
C +GH PG C V+ +A C + GE W
Sbjct: 3134 NVCVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPCAEGEPTWSPWTPWS 3193
Query: 734 FCPLQC-PAHSH-YELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQ 791
C C PA H + C S P + PS AP + C +G + C+ G
Sbjct: 3194 QCSASCGPARCHRHRFCARS-PSAVPSTVAPLPLPATPTPLC---SGPEAEEEPCLLQG- 3248
Query: 792 CGCLHDGRYYPLGEVFYPGPECERRCECGPGGHV-TCQEGAACGPHEECRLEDGVQA--- 847
C G + P G P C R C G C + G + C +G +A
Sbjct: 3249 --CDRAGGWGPWG----PWSHCSRSCGGGLRSRTRACDQPPPQGLGDYC---EGPRAQGE 3299
Query: 848 -CHATGCG--RCLANGGIHYITLDG---RVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEK 901
C A C C A G Y R D C + C+ PG VL
Sbjct: 3300 VCQALPCPVTNCTAIEGAEYSPCGPPCPRSCDDLVHCVWRCQPGCYCPPGQ-----VLSS 3354
Query: 902 NAAGDLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLR 961
N A +Q + + L GQ+ G +A P EGR L T
Sbjct: 3355 NGAICVQPGHCSC----LDLLTGQRHH-PGARLARPDGCNHC-TCLEGR---LNCT---- 3401
Query: 962 LLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSS 1021
+P P G C WS+ + + + + A P
Sbjct: 3402 -----------DLPCPVPGGWCP--------WSE-WTMCSQPCRGQTRSRSRACACPTPQ 3441
Query: 1022 KGCGEGCGPQGCPVCLAEETAPYESNEACGQLRN--------PQGPFATCQAVLSPSEYF 1073
G G G E EAC P GP++ C L S
Sbjct: 3442 HGGAPCTGEAG-------EAGAQHQREACPSYATCPVDGAWGPWGPWSPCDMCLGQSHRS 3494
Query: 1074 RQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRT 1133
R C + G C +P + +S C C +
Sbjct: 3495 RACSRPPTPEGG-------------RPCPGNHTQSRPCQENSTQCTDCGGGQSLHPCGQP 3541
Query: 1134 CQGSCAALSGLTGC---TTRCFEGCECDDRFLLSQGVCIPVQDCGCTH--NGRYLPVNSS 1188
C SC LS + C + C C C L G+C+P C C + +P N S
Sbjct: 3542 CPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRCQYQPGAMGIPENQS 3601
Query: 1189 -----------------LLTSDCSERCSCSSSSGLTCQ-AAGCP-PG 1216
++T C + C+C + L CQ CP PG
Sbjct: 3602 RSAGSRFSSWESLEPGEVVTGPC-DNCTCVAGI-LQCQEVPDCPDPG 3646
Score = 42.7 bits (99), Expect = 0.002
Identities = 58/252 (23%), Positives = 84/252 (33%), Gaps = 63/252 (25%)
Query: 620 PADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLA 679
P + ++ G + + W+ + GE V+ PC + CT G++ + P
Sbjct: 3597 PENQSRSAGSRFSSWE---SLEPGEVVTGPCDN-CTC----------VAGILQCQEVPDC 3642
Query: 680 PCHGLVPPAQYFQGCLLDA----------CQVQGHPGGLCPAVATYVAACQAAGAQLGEW 729
P G+ ++ C + C PG + C+ AG
Sbjct: 3643 PDPGVWSSWGPWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCSTQVCREAG------ 3696
Query: 730 RRPDFCPLQCPAHSHYELC--GDSCPVSCPSLSAPEGCES-ACREGCVCDAGFVLSGDTC 786
CPA Y C G+ CP SC ++ GC S C EGC C G C
Sbjct: 3697 ---------CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLAC 3747
Query: 787 VPVGQC----------GCLHDGRYYPLGEVFYPGPECER----RCECGPGGHVTCQEGAA 832
V C G PLG PG E + R C G+ +C G
Sbjct: 3748 VQECPCVLTAWLLQELGATIGDPGQPLG----PGDELDSGQTLRTSC---GNCSCAHGKL 3800
Query: 833 CGPHEECRLEDG 844
++C DG
Sbjct: 3801 SCSLDDCFEADG 3812
Score = 41.6 bits (96), Expect = 0.005
Identities = 38/140 (27%), Positives = 53/140 (37%), Gaps = 28/140 (20%)
Query: 1123 AHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQ-GVCIPVQDCGCTHNGR 1181
A +C +TC A + C++ GC C SQ G C+P C C H GR
Sbjct: 4933 APGELGLCEQTCL-EMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDHCECWHLGR 4991
Query: 1182 -YLP-------VNSSLLTSD---CSERCS---CSSSSGLTCQAAGCPP----------GR 1217
+LP S L S C++ CS C+ + + C P
Sbjct: 4992 PHLPGSEWQEACESCLCLSGRPVCTQHCSPLTCAQGEEMVLEPGSCCPSCRREAPEEQSP 5051
Query: 1218 VCEVKAEARNCWATRGLCVL 1237
C++ E RN T+G C L
Sbjct: 5052 SCQLLTELRN--FTKGTCYL 5069
Score = 41.2 bits (95), Expect = 0.007
Identities = 37/132 (28%), Positives = 45/132 (34%), Gaps = 28/132 (21%)
Query: 352 CPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGC 411
CP + + C PASC A L+ P C GC C +G +L + CVP + C C
Sbjct: 3090 CPRDKQWLDCAQG-PASC---AELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQD-CPC 3144
Query: 412 WANGTYHEAGSEFWAD-----------GTCSQWCRCGPGGG-----------SLVCTPAS 449
G + GS CS W C G S C PA
Sbjct: 3145 AHEGHLYPPGSTVVRPCENCSCVSGLIANCSSW-PCAEGEPTWSPWTPWSQCSASCGPAR 3203
Query: 450 CGLGEVCGLLPS 461
C C PS
Sbjct: 3204 CHRHRFCARSPS 3215
Score = 41.2 bits (95), Expect = 0.007
Identities = 34/111 (30%), Positives = 43/111 (38%), Gaps = 12/111 (10%)
Query: 1117 CPL-HCPA--HSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQ--GVCIPV 1171
CP+ +C A + YS C C SC L C RC GC C +LS +C+
Sbjct: 3306 CPVTNCTAIEGAEYSPCGPPCPRSC---DDLVHCVWRCQPGCYCPPGQVLSSNGAICVQP 3362
Query: 1172 QDCGCTH--NGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCP-PGRVC 1219
C C G+ + L D C+C L C CP PG C
Sbjct: 3363 GHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGR-LNCTDLPCPVPGGWC 3412
Score = 40.0 bits (92), Expect = 0.016
Identities = 60/231 (25%), Positives = 79/231 (34%), Gaps = 52/231 (22%)
Query: 634 WQVGGAQGC---GECVSKPCPSPCTPEQQESFGGPDACGVIS--ATDGPLA----PCHGL 684
W G ++ C G V + CP P E Q AC V +T P + PC G
Sbjct: 1713 WGQGRSRRCSPLGLLVLQNCPGP---EHQSQACFTAACPVDGEWSTWSPWSVCSEPCRGT 1769
Query: 685 VPPAQYFQGCLLDACQVQGHPGGL--------CPAVATYVAACQAAGAQLGEWRRPDFCP 736
+ + PGGL CP A C +G + + P CP
Sbjct: 1770 MTRQRQCHSPQNGGRTCAALPGGLHSTRQTKPCPQDGCPNATC--SGELMFQPCAP--CP 1825
Query: 737 LQCPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGD-TCVPVGQCGCL 795
L C S C P P GC C G VL + CV QC CL
Sbjct: 1826 LTCDDISGQVTCPPDWPCGSP--------------GCWCPEGQVLGSEGWCVWPRQCPCL 1871
Query: 796 HDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEG--AACGPHEECRLEDG 844
DG Y +PG + C+ CQ+G C + +C ++ G
Sbjct: 1872 VDGARY------WPGQRIKADCQL-----CICQDGRPRRCRLNPDCAVDCG 1911
Score = 40.0 bits (92), Expect = 0.016
Identities = 30/100 (30%), Positives = 34/100 (34%), Gaps = 10/100 (10%)
Query: 1121 CPAHSHYSICTRTCQGSCAALSGLTGCTTR--CFEGCECDDRFLLSQGVCIPVQDCGCTH 1178
C + C C G CA C C GC C L G CIP ++C C H
Sbjct: 4423 CTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIPPEECNCWH 4482
Query: 1179 N-----GRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGC 1213
G L L C E C C L C + GC
Sbjct: 4483 TSAAGAGMTLAPGDRLQLG-CKE-CECRRGE-LHCTSQGC 4519
Score = 39.3 bits (90), Expect = 0.027
Identities = 65/269 (24%), Positives = 86/269 (31%), Gaps = 72/269 (26%)
Query: 259 CRGSCP-TCPEDR--LEQYEGPGFCGPLAPGTGGPFTTCH--AHVPPESFFKGCVL--DV 311
C G P CP D+ L+ +GP C L+ G TCH H P G +L +V
Sbjct: 3082 CAGPVPGMCPRDKQWLDCAQGPASCAELS-APRGTNQTCHPGCHCP-----SGMLLLNNV 3135
Query: 312 CMGGGDHDIL------------------CKALASYVAACQA-----AGVVIEDWRAQVGC 348
C+ D C ++ +A C + W C
Sbjct: 3136 CVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPCAEGEPTWSPWTPWSQC 3195
Query: 349 EITC-PENSHYEVCGPPCPASCPS-----PAPLTTPAVCEGPCVEGCQCDAGFVLSADRC 402
+C P H P++ PS P P T +C GP E C + DR
Sbjct: 3196 SASCGPARCHRHRFCARSPSAVPSTVAPLPLPATPTPLCSGPEAEEEPC---LLQGCDRA 3252
Query: 403 VPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCT-PASCGLG-------- 453
G G W ++ CS+ C G + C P GLG
Sbjct: 3253 ----GGWGPWGPWSH------------CSRSCGGGLRSRTRACDQPPPQGLGDYCEGPRA 3296
Query: 454 --EVCGLLPSGQHGCQPVSTAECQAWGDP 480
EVC LP C + AE G P
Sbjct: 3297 QGEVCQALPCPVTNCTAIEGAEYSPCGPP 3325
Score = 38.5 bits (88), Expect = 0.046
Identities = 34/117 (29%), Positives = 44/117 (37%), Gaps = 15/117 (12%)
Query: 345 QVGC-EITCPENSHYEVCGPPCPASCPS-PAPLTTPAVCEGPCVE-GCQCDAGFVLSADR 401
Q GC TC ++ C P CP +C +T P + PC GC C G VL ++
Sbjct: 1804 QDGCPNATCSGELMFQPCAP-CPLTCDDISGQVTCPP--DWPCGSPGCWCPEGQVLGSEG 1860
Query: 402 CVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGL 458
C C +G + G AD Q C C G P C L C +
Sbjct: 1861 WCVWPRQCPCLVDGARYWPGQRIKAD---CQLCICQDG------RPRRCRLNPDCAV 1908
Score = 37.4 bits (85), Expect = 0.10
Identities = 33/124 (26%), Positives = 44/124 (35%), Gaps = 27/124 (21%)
Query: 1058 GPFATCQAVLSPSEYFR--QCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDS 1115
GP+ C E R +C C ++ C T C+ AG
Sbjct: 3652 GPWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCS-----TQVCREAG---------- 3696
Query: 1116 FCPLHCPAHSHYSICT--RTCQGSCAALSGLTGCTTR-CFEGCECDDRFLLSQGVCIPVQ 1172
CPA Y C C SCA ++ GC + C EGC C + + C VQ
Sbjct: 3697 -----CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLAC--VQ 3749
Query: 1173 DCGC 1176
+C C
Sbjct: 3750 ECPC 3753
Score = 33.5 bits (75), Expect = 1.5
Identities = 36/148 (24%), Positives = 45/148 (30%), Gaps = 29/148 (19%)
Query: 260 RGSCP---TCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGG 316
R +CP TCP D G GP GP++ C + + C GG
Sbjct: 3460 REACPSYATCPVD--------GAWGPW-----GPWSPCDMCLGQSHRSRACSRPPTPEGG 3506
Query: 317 DHDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLT 376
C + CQ D C CG PCP SC +P +
Sbjct: 3507 RP---CPGNHTQSRPCQENSTQCTD----------CGGGQSLHPCGQPCPRSCQDLSPGS 3553
Query: 377 TPAVCEGPCVEGCQCDAGFVLSADRCVP 404
C C C G + CVP
Sbjct: 3554 VCQPGSVGCQPTCGCPLGQLSQDGLCVP 3581
Score = 32.3 bits (72), Expect = 3.3
Identities = 25/63 (39%), Positives = 26/63 (41%), Gaps = 8/63 (12%)
Query: 345 QVGCEITCPENSHYEVCGPP--CPASCPSPAPLTTPAVC--EGPCVEGCQCDAGFVLSAD 400
QV E CP Y C P CP SC A +T C EG C EGC C G
Sbjct: 3690 QVCREAGCPAGRLYRECQPGEGCPFSC---AHVTQQVGCFSEG-CEEGCHCPEGTFQHRL 3745
Query: 401 RCV 403
CV
Sbjct: 3746 ACV 3748
>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
Length = 5765
Score = 355 bits (912), Expect = 1e-97
Identities = 341/1316 (25%), Positives = 490/1316 (37%), Gaps = 218/1316 (16%)
Query: 75 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLTPFTVTTKNENRGNPAVSYV 134
C WGD HY +FDG F F G CNYV + F V + G+ V V
Sbjct: 77 CSTWGDFHYKTFDGDVFRFPGLCNYVFSEH-----CRAAYEDFNVQLRRGLVGSRPV--V 129
Query: 135 RVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVS 194
V + A G + G V +NG LP S R + S + L ++
Sbjct: 130 TRVVIKAQGLVLEASN---GSVLINGQREELPYS----RTGLLVEQSGDYIKVSIRLVLT 182
Query: 195 YDWNWRVD--VTLPSSYHGAVCGLCGNMDRNPNNDQVFP-NGTLAPSIPIWGGSWRAPGW 251
+ WN + L Y CGLCG+ + P ++ + N L P +G + G
Sbjct: 183 FLWNGEDSALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLTPLQ--FGNLQKLDGP 240
Query: 252 DPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV 311
C D C ++ G C G F CHA V ++ C D+
Sbjct: 241 TEQCPDPLPLPAGNCTDEE-------GICHRTLLGPA--FAECHALVDSTAYLAACAQDL 291
Query: 312 CMGGGDHDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPS 371
C C Y C AG +WR C TCP N ++ CG PC +C +
Sbjct: 292 CRCP---TCPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSN 348
Query: 372 PAPLTTPAVCEGPCVEGCQCDAGFV------LSADRCVPLNNGCGCWANGTYHEAGSEFW 425
P +CE CV+GC C G ++ C+PL C C G + G+ F
Sbjct: 349 P---QRAQLCEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQ-CPCTHGGRTYSPGTSF- 403
Query: 426 ADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTL 485
+ TCS C C GG C C C G H T
Sbjct: 404 -NTTCSS-CTC--SGGLWQCQDLPC--------------------PGTCSVQGGAHISTY 439
Query: 486 DGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTLQIYNHSLT 544
D +D G C Y+LS C +FTV G + + ++VTL +
Sbjct: 440 DEKLYDLHGDCSYVLSKKC-----ADSSFTVLAELRKCGLTDNENCLKAVTLSLDGGDTA 494
Query: 545 LSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVR--LRVP 602
+ + + ++ ++ LP ++ S +VV T GL L ++ +R+
Sbjct: 495 IRVQADGGVFLNSIYTQLPLSAANITLFTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLD 554
Query: 603 AAYAASLCGLCGNYNQDPADDLKAVGG-----KPAGWQVGGAQGCGECVSKPCPSPCTPE 657
A+ +CGLCGN+NQ+ ADD A+ G A AQ PC+
Sbjct: 555 PAHQGQMCGLCGNFNQNQADDFTALSGVVEATGAAFANTWKAQAACANARNSFEDPCSLS 614
Query: 658 QQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVA 717
+ C ++ + + CH ++ P + C+ D C + LC A+++YV
Sbjct: 615 VENENYARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNCERSEDCLCAALSSYVH 674
Query: 718 ACQAAGAQLGEWRRPDFCP---LQCPAHSHYELCGDSCPVSCPSLSAPEGCESAC---RE 771
AC A G QL +W R C CP Y D+C +C LS + S +
Sbjct: 675 ACAAKGVQLSDW-RDGVCTKYMQNCPKSQRYAYVVDACQPTCRGLSEADVTCSVSFVPVD 733
Query: 772 GCVCDAG-FVLSGDTCVPVGQCGCLHDGRYYPLGEVFY---------------------- 808
GC C AG F+ CVP +C C G GEV +
Sbjct: 734 GCTCPAGTFLNDAGACVPAQECPCYAHGTVLAPGEVVHDEGAVCSCTGGKLSCLGASLQK 793
Query: 809 --------------------PGPECERRCE----------------CGPG------GHVT 826
PG EC R C C PG G
Sbjct: 794 STGCAAPMVYLDCSNSSAGTPGAECLRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGCI 853
Query: 827 CQEGAAC-------GPHEECRLEDGVQAC--------HATGCGRCLANGGIHYITLDGRV 871
+E C P E R++ C H G C+A G H+IT DG
Sbjct: 854 AEEDCPCVHNEATYKPGETIRVDCNTCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDR 913
Query: 872 YDLHGSCSYVLAQ-VCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVSLAQGQQVTVD 930
Y GSC Y+LAQ C F IV E G T + + L +
Sbjct: 914 YSFEGSCEYILAQDYCGDNTTHGTFRIVTENIPCGTTG----TTCSKAIKLFVESYELIL 969
Query: 931 GEAVALPVAVG-----RVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGL 985
E VA G ++ G +V++ T G+ + +D + + + ++GR+CGL
Sbjct: 970 QEGTFKAVARGPGGDPPYKIRYMGIFLVIE-THGMAVSWDRKTSVFIRLHQDYKGRVCGL 1028
Query: 986 CGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEGCGPQGCPVCLAEETAPYE 1045
CGNF+ N +DF + S FG +W++ S C + P+ C A
Sbjct: 1029 CGNFDDNAINDFATRSRSVVGDALEFGNSWKL---SPSCPDALAPK--DPCTANPFRKSW 1083
Query: 1046 SNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCA--QKGDKAFLCRSLAAYTAACQA 1103
+ + C L P FA C++ + ++Y+ CV D CA GD C ++AAY AC
Sbjct: 1084 AQKQCSILHGP--TFAACRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACHD 1141
Query: 1104 AGVAVKPWRTDSFCPLHCPAHS-------HYSICTRTCQGSC--------AALSGLTGCT 1148
AG+ V WRT CPL C ++ HY C C +C L GL GC
Sbjct: 1142 AGLCVS-WRTPDTCPLFCDFYNPHGGCEWHYQPCGAPCLKTCRNPSGHCLVDLPGLEGCY 1200
Query: 1149 TRCFEGCECDDRFLLSQGVCIPVQDCGC-THNGRYLPVNSSLLTSDCSERCSCSSSSGLT 1207
+C F Q C V CGC +G Y V + + T++ + C+C + SG+
Sbjct: 1201 PKC---PPSQPFFNEDQMKC--VAQCGCYDKDGNYYDVGARVPTAENCQSCNC-TPSGIQ 1254
Query: 1208 C----QAAGCP-PGRVCEVKAEARNCWATRGLCVLSV-GANLTTFDGARGATTSPG 1257
C +A C R + N G C++++ G+N T R A PG
Sbjct: 1255 CAHSLEACTCTYEDRTYSYQDVIYNTTDGLGACLIAICGSNGTII---RKAVACPG 1307
Score = 305 bits (781), Expect = 2e-82
Identities = 282/1040 (27%), Positives = 397/1040 (38%), Gaps = 206/1040 (19%)
Query: 474 CQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRS 533
C WGD HY T DG F F G C Y+ S C E+F V + GS+ V TR
Sbjct: 77 CSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCRA---AYEDFNVQLRRGLVGSRPV-VTRV 132
Query: 534 VTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDG 593
V I L L A L ++G LP+ LL SG + V+ L+ ++G
Sbjct: 133 V---IKAQGLVLEASNGSVL-INGQREELPYSRTGLL-VEQSGDYIKVSIRLVLTFLWNG 187
Query: 594 DSFVRLRVPAAYAASLCGLCGNYNQDPA-DDLKAVGGKPAGWQVGGAQ---GCGECVSKP 649
+ L + YA CGLCG++N PA ++ A + Q G Q G E P
Sbjct: 188 EDSALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLTPLQFGNLQKLDGPTEQCPDP 247
Query: 650 CPSP---CTPEQQESFGGPDACGVISATD-GP-LAPCHGLVPPAQYFQGCLLDACQVQGH 704
P P CT E+ G+ T GP A CH LV Y C D C+
Sbjct: 248 LPLPAGNCTDEE----------GICHRTLLGPAFAECHALVDSTAYLAACAQDLCRCPTC 297
Query: 705 PGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEG 764
P C Y C AG Q WR P+ CP CP + ++ CG C +C + +
Sbjct: 298 P---CATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSNPQRAQL 354
Query: 765 CESACREGCVCDAG---FVLSGDT---CVPVGQCGCLHDGRYYPLGEVFYPGPECERRCE 818
CE C +GC C G VL T C+P+GQC C H GR Y G F
Sbjct: 355 CEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHGGRTYSPGTSF----------- 403
Query: 819 CGPGGHVTCQEGAACGPHEECRLEDGVQACHATGC-GRCLANGGIHYITLDGRVYDLHGS 877
+ TC C G+ C C G C GG H T D ++YDLHG
Sbjct: 404 -----NTTCSS---------CTCSGGLWQCQDLPCPGTCSVQGGAHISTYDEKLYDLHGD 449
Query: 878 CSYVLAQVCHPKPGDEDFSIVLEKNAAG--DLQRLLVTVAGQVVSLAQGQQVTVDGEA-- 933
CSYVL++ C D F+++ E G D + L V + +V DG
Sbjct: 450 CSYVLSKKC----ADSSFTVLAELRKCGLTDNENCLKAVTLSLDGGDTAIRVQADGGVFL 505
Query: 934 ----VALPVAVGRVRV-TAEGRNMVLQTTKGLRLLFD--GDAHLLMSIPSPFRGRLCGLC 986
LP++ + + T +V+QT GL+LL + + + +G++CGLC
Sbjct: 506 NSIYTQLPLSAANITLFTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLDPAHQGQMCGLC 565
Query: 987 GNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEGCGPQGCPVCLAEETAPYES 1046
GNFN N +DDF +G ++ F W+ + C P L+ E Y +
Sbjct: 566 GNFNQNQADDFTALSGVVEATGAAFANTWKAQAA---CANARNSFEDPCSLSVENENY-A 621
Query: 1047 NEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGV 1106
C +L +P F+ C ++++P + C++D C + + LC +L++Y AC A GV
Sbjct: 622 RHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNCERSEDCLCAALSSYVHACAAKGV 681
Query: 1107 AVKPWRTDSFCPLH---CPAHSHYSICTRTCQGSCAALSGLTGCTTRC------FEGCEC 1157
+ WR D C + CP Y+ CQ +C GL+ C +GC C
Sbjct: 682 QLSDWR-DGVCTKYMQNCPKSQRYAYVVDACQPTCR---GLSEADVTCSVSFVPVDGCTC 737
Query: 1158 D-DRFLLSQGVCIPVQD----------------------CGCTHNGRYLPVNSSLLTS-- 1192
FL G C+P Q+ C CT G+ + +SL S
Sbjct: 738 PAGTFLNDAGACVPAQECPCYAHGTVLAPGEVVHDEGAVCSCT-GGKLSCLGASLQKSTG 796
Query: 1193 --------DCSERCS--------------------------CSSSSGLTCQAAG------ 1212
DCS + C GL +G
Sbjct: 797 CAAPMVYLDCSNSSAGTPGAECLRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGCIAEE 856
Query: 1213 -CP---------PGRVCEVKAEARNCWATR---------GLCVLSVGANLTTFDGARGAT 1253
CP PG V C R G CV + TFDG R +
Sbjct: 857 DCPCVHNEATYKPGETIRVDCNTCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDRYSF 916
Query: 1254 TSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWV 1313
Y L+ G T +R+V E C G T +K + +
Sbjct: 917 EGSCEYILAQDYCGDNTTHGTFRIVTENIPC----------------GTTGTTCSKAIKL 960
Query: 1314 NGLRVDLPAEKLASVSVSRTPDGS----------LLVRQKAGVQVWLGANGKVAVIVSND 1363
+L ++ +V+R P G LV + G+ V V + + D
Sbjct: 961 FVESYELILQEGTFKAVARGPGGDPPYKIRYMGIFLVIETHGMAVSWDRKTSVFIRLHQD 1020
Query: 1364 HAGKLCGACGNFDGDQTNDW 1383
+ G++CG CGNFD + ND+
Sbjct: 1021 YKGRVCGLCGNFDDNAINDF 1040
Score = 236 bits (603), Expect = 9e-62
Identities = 250/958 (26%), Positives = 363/958 (37%), Gaps = 195/958 (20%)
Query: 43 SPDPCHGVTCRPQETCKEQGGQGVC--LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYV 100
SP TC +C GG C LP TC + G H ++D + +D G C+YV
Sbjct: 398 SPGTSFNTTC---SSCTCSGGLWQCQDLP-CPGTCSVQGGAHISTYDEKLYDLHGDCSYV 453
Query: 101 LATTGCLGVSTQGLTPFTVT--TKNENRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRV 158
L+ C S L T NEN ++ VT++ G + +I G V +
Sbjct: 454 LSKK-CADSSFTVLAELRKCGLTDNEN-------CLKAVTLSLDGGDTAIRVQADGGVFL 505
Query: 159 NGVLTALPVSVADGRISVAQGASKALLV-ADFGLQVSYDWN--WRVDVTLPSSYHGAVCG 215
N + T LP+S A+ I++ +S ++V GLQ+ +V V L ++ G +CG
Sbjct: 506 NSIYTQLPLSAAN--ITLFTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLDPAHQGQMCG 563
Query: 216 LCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYE 275
LCGN ++N +D +G + + + +W+A + C E+ E Y
Sbjct: 564 LCGNFNQNQADDFTALSGVVEATGAAFANTWKAQAACANARNSFEDPCSLSVEN--ENY- 620
Query: 276 GPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAA 335
+C L F+ CH+ + P+ F C+ D C D LC AL+SYV AC A
Sbjct: 621 ARHWCSRLTDPNSA-FSRCHSIINPKPFHSNCMFDTCNCERSEDCLCAALSSYVHACAAK 679
Query: 336 GVVIEDWRAQVGCEI--TCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDA 393
GV + DWR V + CP++ Y C +C + V+GC C A
Sbjct: 680 GVQLSDWRDGVCTKYMQNCPKSQRYAYVVDACQPTCRGLSEADVTCSVSFVPVDGCTCPA 739
Query: 394 G-FVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPAS--- 449
G F+ A CVP C C+A+GT G +G C GG L C AS
Sbjct: 740 GTFLNDAGACVPAQE-CPCYAHGTVLAPGEVVHDEGAV-----CSCTGGKLSCLGASLQK 793
Query: 450 ----------------------------------------CGLGEVC--GLLPSGQHGCQ 467
C G VC GL+ G GC
Sbjct: 794 STGCAAPMVYLDCSNSSAGTPGAECLRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGCI 853
Query: 468 PVSTAEC------------------------QAWGDPHYVTL--------------DGHR 489
C + W H + L DG R
Sbjct: 854 AEEDCPCVHNEATYKPGETIRVDCNTCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDR 913
Query: 490 FDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARW 549
+ F+G+CEY+L+ G F + N G+ + ++++ L + ++ L L
Sbjct: 914 YSFEGSCEYILAQDYCGDNTTHGTFRIVTENIPCGTTGTTCSKAIKLFVESYELILQ--- 970
Query: 550 PRKLQVDGVFVAL--------PFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRV 601
+G F A+ P+++ + +V T G+++++D + V +R+
Sbjct: 971 ------EGTFKAVARGPGGDPPYKIRYM-------GIFLVIETHGMAVSWDRKTSVFIRL 1017
Query: 602 PAAYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGEC--VSKPCP------SP 653
Y +CGLCGN++ + +D VG A G +S CP P
Sbjct: 1018 HQDYKGRVCGLCGNFDDNAINDFATRSRS----VVGDALEFGNSWKLSPSCPDALAPKDP 1073
Query: 654 CTPEQQESFGGPDACGVISATDGP-LAPCHGLVPPAQYFQGCLLDACQVQ--GHPGGLCP 710
CT C ++ GP A C V +Y++ C+ DAC G C
Sbjct: 1074 CTANPFRKSWAQKQCSIL---HGPTFAACRSQVDSTKYYEACVNDACACDSGGDCECFCT 1130
Query: 711 AVATYVAACQAAGAQLGEWRRPDFCPLQCPAHS-------HYELCGDSCPVSC--PS--- 758
AVA Y AC AG + WR PD CPL C ++ HY+ CG C +C PS
Sbjct: 1131 AVAAYAQACHDAGLCV-SWRTPDTCPLFCDFYNPHGGCEWHYQPCGAPCLKTCRNPSGHC 1189
Query: 759 ---LSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCL-HDGRYYPLGEVFYPGPECE 814
L EGC C + + D V QCGC DG YY +G C+
Sbjct: 1190 LVDLPGLEGCYPKCP-----PSQPFFNEDQMKCVAQCGCYDKDGNYYDVGARVPTAENCQ 1244
Query: 815 RRCECGPGGHVTCQEGAACGPHEECR----------LEDGVQACHATGCGRCLANGGI 862
C C P G AC E R DG+ AC CG +NG I
Sbjct: 1245 -SCNCTPSGIQCAHSLEACTCTYEDRTYSYQDVIYNTTDGLGACLIAICG---SNGTI 1298
Score = 126 bits (317), Expect = 1e-28
Identities = 127/461 (27%), Positives = 177/461 (38%), Gaps = 40/461 (8%)
Query: 41 LLSPDPCHGVTCRPQET-CKEQGGQGVCLPNYEATCW--LWGDPHYHSFDGRKFDFQGTC 97
LL P P VTC + K C +YE C +WG HY +FDG + F+G C
Sbjct: 5041 LLDPKPVANVTCVNKHLPIKVSDPSQPCDFHYECECICSMWGGSHYSTFDGTSYTFRGNC 5100
Query: 98 NYVL-----ATTGCLGVSTQGLTPFTVTTKNENRGNPAVSYVRVVTVAALGTNISIHKDE 152
YVL A G L + T R A+S + ++ + T +H E
Sbjct: 5101 TYVLMREIHARFGNLSLYLDNHYCTASATAAAARCPRALS-IHYKSMDIVLTVTMVHGKE 5159
Query: 153 IGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRV-DVTLP-SSYH 210
G + + + + S +SV + + + G+ V++ N +V LP S +H
Sbjct: 5160 EGLILFDQIPVSSGFSKNGVLVSVLGTTTMRVDIPALGVSVTF--NGQVFQARLPYSLFH 5217
Query: 211 GAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAP-GWDPLCWDECRGSCPTC-PE 268
G CG N +D + +GT A S +W P CW G+ PT P
Sbjct: 5218 NNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTWLVPDSRKDGCWAP-TGTPPTASPA 5276
Query: 269 DRLEQYEGPGFCGP---LAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKAL 325
+ P C P F CH VPP FF C+ D C G ++ C++L
Sbjct: 5277 APVSSTPTPTPCPPQPLCDLMLSQVFAECHNLVPPGPFFNACISDHCR--GRLEVPCQSL 5334
Query: 326 ASYVAACQAAGVVIEDWRAQVG--CEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEG 383
+Y C+A G V DWR G C++TCP Y+ CGP PA+C S EG
Sbjct: 5335 EAYAELCRARG-VCSDWRGATGGLCDLTCPPTKVYKPCGPIQPATCNS---RNQSPQLEG 5390
Query: 384 PCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSL 443
EGC C +L C C + + E W Q C C G S+
Sbjct: 5391 -MAEGCFCPEDQILFNAHMGICVQACPCVGPDGFPKFPGERWVSN--CQSCVCDEGSVSV 5447
Query: 444 VCTPASCGL----------GEVCGLLPSGQHGCQPVSTAEC 474
C P C G V P ++ C P + C
Sbjct: 5448 QCKPLPCDAQGQPPPCNRPGFVTVTRPRAENPCCPETVCVC 5488
Score = 112 bits (280), Expect = 2e-24
Identities = 136/554 (24%), Positives = 194/554 (35%), Gaps = 98/554 (17%)
Query: 739 CPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCG----- 793
C H + +CP S P +S+ + GC D +P+ Q
Sbjct: 4976 CNQHCDIDRFQGACPTSPPPVSSAPLSSPSPAPGC----------DNAIPLRQVNETWTL 5025
Query: 794 -------CLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQ 846
C+ D R L + P +VTC H ++ D Q
Sbjct: 5026 ENCTVARCVGDNRVVLL--------------DPKPVANVTC-----VNKHLPIKVSDPSQ 5066
Query: 847 ACHATGCGRCLAN--GGIHYITLDGRVYDLHGSCSYVLAQVCHPKPG------DEDFSIV 898
C C+ + GG HY T DG Y G+C+YVL + H + G D +
Sbjct: 5067 PCDFHYECECICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTA 5126
Query: 899 LEKNAAGDLQRLLVTVAGQV-----VSLAQGQQ---VTVDGEAVALPVAVGRVRVTAEGR 950
AA R L + V++ G++ + D V+ + V V+ G
Sbjct: 5127 SATAAAARCPRALSIHYKSMDIVLTVTMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGT 5186
Query: 951 NMVLQTTK--GLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSV 1008
+ G+ + F+G S F G CG N DD + +G+ A+S
Sbjct: 5187 TTMRVDIPALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASC 5246
Query: 1009 ETFGAAWRVPGSSK-GCGEGCG-----PQGCPVCLAEETAPYESNEACGQLRNPQGPFAT 1062
+ W VP S K GC G PV P C + + FA
Sbjct: 5247 KDMAKTWLVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQPLCDLMLSQ--VFAE 5304
Query: 1063 CQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWR--TDSFCPLH 1120
C ++ P +F C+ D C +G C+SL AY C+A GV WR T C L
Sbjct: 5305 CHNLVPPGPFFNACISDHC--RGRLEVPCQSLEAYAELCRARGVC-SDWRGATGGLCDLT 5361
Query: 1121 CPAHSHYSICTRTCQGSCAA------LSGLTGCTTRCFEGCEC-DDRFLLSQGVCIPVQD 1173
CP Y C +C + L G+ EGC C +D+ L + + I VQ
Sbjct: 5362 CPPTKVYKPCGPIQPATCNSRNQSPQLEGMA-------EGCFCPEDQILFNAHMGICVQA 5414
Query: 1174 CGCTHNGRYLPVNSSLLTSDCSERCSCSSSS------GLTCQAAGCP-----PGRVCEVK 1222
C C + S+C + C C S L C A G P PG V +
Sbjct: 5415 CPCVGPDGFPKFPGERWVSNC-QSCVCDEGSVSVQCKPLPCDAQGQPPPCNRPGFVTVTR 5473
Query: 1223 AEARNCWATRGLCV 1236
A N +CV
Sbjct: 5474 PRAENPCCPETVCV 5487
Score = 93.2 bits (230), Expect = 2e-18
Identities = 127/558 (22%), Positives = 203/558 (36%), Gaps = 109/558 (19%)
Query: 322 CKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEV--CGPPCPASCP--SPAPLTT 377
C+A + + G VI + + GC N H ++ CP S P S APL++
Sbjct: 4948 CRAFGQFFSP----GEVIYNKTDRAGCHFYAVCNQHCDIDRFQGACPTSPPPVSSAPLSS 5003
Query: 378 PAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCG 437
P+ G D +PL +E W C+ RC
Sbjct: 5004 PSPAPG---------------CDNAIPLRQV-------------NETWTLENCTV-ARCV 5034
Query: 438 PGGGSLVCTP-----ASCGLGEVCGLLPSGQHGCQPVSTAEC--QAWGDPHYVTLDGHRF 490
++ P +C + + C EC WG HY T DG +
Sbjct: 5035 GDNRVVLLDPKPVANVTCVNKHLPIKVSDPSQPCDFHYECECICSMWGGSHYSTFDGTSY 5094
Query: 491 DFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYT----RSVTLQIYNHSLTLS 546
F+G C Y+L H N ++ + N + + A + R++++ + + L+
Sbjct: 5095 TFRGNCTYVLMREIHA---RFGNLSLYLDNHYCTASATAAAARCPRALSIHYKSMDIVLT 5151
Query: 547 -----ARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTS-GLSLAFDGDSFVRLR 600
+ + D + V+ F + +L + L + V + G+S+ F+G F + R
Sbjct: 5152 VTMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMRVDIPALGVSVTFNGQVF-QAR 5210
Query: 601 VP-AAYAASLCGLCGNYNQDPADDLKAVGGKPAG--------WQVGGAQ--GC------- 642
+P + + + G CG + DD G A W V ++ GC
Sbjct: 5211 LPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTWLVPDSRKDGCWAPTGTP 5270
Query: 643 ------GECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLL 696
S P P+PC P+ C ++ + A CH LVPP +F C+
Sbjct: 5271 PTASPAAPVSSTPTPTPCPPQ--------PLCDLMLSQ--VFAECHNLVPPGPFFNACIS 5320
Query: 697 DACQVQGHPGGLCPAVATYVAACQAAGAQLGEWR--RPDFCPLQCPAHSHYELCGDSCPV 754
D C +G C ++ Y C+A G +WR C L CP Y+ CG P
Sbjct: 5321 DHC--RGRLEVPCQSLEAYAELCRARGV-CSDWRGATGGLCDLTCPPTKVYKPCGPIQPA 5377
Query: 755 SCPSLSAPEGCESACREGCVCDAGFVL-SGDTCVPVGQCGCLHDGRYYPLGEVFYPGPEC 813
+C S + E EGC C +L + + V C C+ P G +PG
Sbjct: 5378 TCNSRNQSPQLEGMA-EGCFCPEDQILFNAHMGICVQACPCVG-----PDGFPKFPGERW 5431
Query: 814 ERRCECGPGGHVTCQEGA 831
C+ C EG+
Sbjct: 5432 VSNCQ-----SCVCDEGS 5444
Score = 39.3 bits (90), Expect = 0.027
Identities = 53/213 (24%), Positives = 72/213 (33%), Gaps = 53/213 (24%)
Query: 602 PAAYAASLCGLCGNYNQDPA----DDLKAVGGKPAGWQVGGAQG--CGECVSKPCPSP-- 653
P A +C QDP +D P G++ G CGECV C +P
Sbjct: 5540 PGALPCHMCTCLSGDTQDPTVQCQEDACNNTTCPQGFEYKRVAGQCCGECVQTACLTPDG 5599
Query: 654 ----------------CTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLD 697
CT E+ GG A+ ++ C G + C D
Sbjct: 5600 QPVQLNETWVNSHVDNCTVYLCEAEGGVHLLTPQPASCPDVSSCRGSLRKTGCCYSCEED 5659
Query: 698 ACQVQ------GHPG-----------GLCPAVATYVAACQAAGAQLG--EWRR--PDFCP 736
+CQV+ H G G CP + Y A QA Q + RR + P
Sbjct: 5660 SCQVRINTTILWHQGCETEVNITFCEGSCPGASKYSAEAQAMQHQCTCCQERRVHEETVP 5719
Query: 737 LQCP-------AHSHYELCGDSCPVSCPSLSAP 762
L CP ++H + CG P P+ AP
Sbjct: 5720 LHCPNGSAILHTYTHVDECG-CTPFCVPAPMAP 5751
>gi|161019170 mucin 5AC [Homo sapiens]
Length = 6207
Score = 346 bits (888), Expect = 8e-95
Identities = 340/1345 (25%), Positives = 487/1345 (36%), Gaps = 242/1345 (17%)
Query: 75 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLTPFTVTTKNENRGNPAVSYV 134
C WGD HY +FDG F F G CNYV + F V + G+ V V
Sbjct: 733 CSTWGDFHYKTFDGDVFRFPGLCNYVFSEH-----CRAAYEDFNVQLRRGLVGSRPV--V 785
Query: 135 RVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVS 194
V + A G + G V +NG LP S R + S + L ++
Sbjct: 786 TRVVIKAQGLVLEASN---GSVLINGQREELPYS----RTGLLVEQSGDYIKVSIRLVLT 838
Query: 195 YDWNWRVD--VTLPSSYHGAVCGLCGNMDRNPNNDQVFP-NGTLAPSIPIWGGSWRAPGW 251
+ WN + L Y CGLCG+ + P ++ + N L P +G + G
Sbjct: 839 FLWNGEDSALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLTPLQ--FGNLQKLDGP 896
Query: 252 DPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV 311
C D C ++ G C G F CHA V ++ C D+
Sbjct: 897 TEQCPDPLPLPAGNCTDEE-------GICHRTLLGPA--FAECHALVDSTAYLAACAQDL 947
Query: 312 CMGGGDHDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPS 371
C C Y C AG +WR C TCP N ++ CG PC +C +
Sbjct: 948 CRCP---TCPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSN 1004
Query: 372 PAPLTTPAVCEGPCVEGCQCDAGFV------LSADRCVPLNNGCGCWANGTYHEAGSEFW 425
P +CE CV+GC C G ++ C+PL C C G + G+ F
Sbjct: 1005 P---QRAQLCEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQ-CPCTHGGRTYSPGTSF- 1059
Query: 426 ADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTL 485
+ TCS C C GG C C C G H T
Sbjct: 1060 -NTTCSS-CTC--SGGLWQCQDLPC--------------------PGTCSVQGGAHISTY 1095
Query: 486 DGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTLQIYNHSLT 544
D +D G C Y+LS C +FTV G + + ++VTL +
Sbjct: 1096 DEKLYDLHGDCSYVLSKKC-----ADSSFTVLAELRKCGLTDNENCLKAVTLSLDGGDTA 1150
Query: 545 LSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVR--LRVP 602
+ + + ++ ++ LP ++ S +VV T GL L ++ +R+
Sbjct: 1151 IRVQADGGVFLNSIYTQLPLSAANITLFTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLD 1210
Query: 603 AAYAASLCGLCGNYNQDPADDLKAVGG-----KPAGWQVGGAQGCGECVSKPCPSPCTPE 657
A+ +CGLCGN+NQ+ ADD A+ G A AQ PC+
Sbjct: 1211 PAHQGQMCGLCGNFNQNQADDFTALSGVVEATGAAFANTWKAQAACANARNSFEDPCSLS 1270
Query: 658 QQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVA 717
+ C ++ + + CH ++ P + C+ D C + LC A+++YV
Sbjct: 1271 VENENYARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNCERSEDCLCAALSSYVH 1330
Query: 718 ACQAAGAQLGEWRRPDFCP---LQCPAHSHYELCGDSCPVSCPSLSAPEGCESAC---RE 771
AC A G QL +W R C CP Y D+C +C LS + S +
Sbjct: 1331 ACAAKGVQLSDW-RDGVCTKYMQNCPKSQRYAYVVDACQPTCRGLSEADVTCSVSFVPVD 1389
Query: 772 GCVCDAG-FVLSGDTCVPVGQCGCLHDGRYYPLGEVFY---------------------- 808
GC C AG F+ CVP +C C G GEV +
Sbjct: 1390 GCTCPAGTFLNDAGACVPAQECPCYAHGTVLAPGEVVHDEGAVCSCTGGKLSCLGASLQK 1449
Query: 809 --------------------PGPECERRCE----------------CGPG------GHVT 826
PG EC R C C PG G
Sbjct: 1450 STGCAAPMVYLDCSNSSAGTPGAECLRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGCI 1509
Query: 827 CQEGAAC-------GPHEECRLEDGVQAC--------HATGCGRCLANGGIHYITLDGRV 871
+E C P E R++ C H G C+A G H+IT DG
Sbjct: 1510 AEEDCPCVHNEATYKPGETIRVDCNTCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDR 1569
Query: 872 YDLHGSCSYVLAQ-VCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVSLAQGQQVTVD 930
Y GSC Y+LAQ C F IV E G V + V+
Sbjct: 1570 YSFEGSCEYILAQDYCGDNTTHGTFRIVTENIPCGTTGTTCSKAIKLFVEVRTAPAVSTP 1629
Query: 931 GEAVALP----------------------VAVGRVRVTAEGRN------------MVLQT 956
A P + G + A G ++
Sbjct: 1630 DPAANEPAPREASVGFRQRLPPLQSYELILQEGTFKAVARGPGGDPPYKIRYMGIFLVIE 1689
Query: 957 TKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWR 1016
T G+ + +D + + + ++GR+CGLCGNF+ N +DF + S FG +W+
Sbjct: 1690 THGMAVSWDRKTSVFIRLHQDYKGRVCGLCGNFDDNAINDFATRSRSVVGDALEFGNSWK 1749
Query: 1017 VPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQC 1076
+ S C + P+ C A + + C L P FA C++ + ++Y+ C
Sbjct: 1750 L---SPSCPDALAPK--DPCTANPFRKSWAQKQCSILHGP--TFAACRSQVDSTKYYEAC 1802
Query: 1077 VYDLCA--QKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHS-------HY 1127
V D CA GD C ++AAY AC AG+ V WRT CPL C ++ HY
Sbjct: 1803 VNDACACDSGGDCECFCTAVAAYAQACHDAGLCVS-WRTPDTCPLFCDFYNPHGGCEWHY 1861
Query: 1128 SICTRTCQGSC--------AALSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQDCGC-TH 1178
C C +C L GL GC +C F Q C V CGC
Sbjct: 1862 QPCGAPCLKTCRNPSGHCLVDLPGLEGCYPKC---PPSQPFFNEDQMKC--VAQCGCYDK 1916
Query: 1179 NGRYLPVNSSLLTSDCSERCSCSSSSGLTC----QAAGCP-PGRVCEVKAEARNCWATRG 1233
+G Y V + + T++ + C+C + SG+ C +A C R + N G
Sbjct: 1917 DGNYYDVGARVPTAENCQSCNC-TPSGIQCAHSLEACTCTYEDRTYSYQDVIYNTTDGLG 1975
Query: 1234 LCVLSV-GANLTTFDGARGATTSPG 1257
C++++ G+N T R A PG
Sbjct: 1976 ACLIAICGSNGTII---RKAVACPG 1997
Score = 226 bits (577), Expect = 9e-59
Identities = 253/976 (25%), Positives = 361/976 (36%), Gaps = 197/976 (20%)
Query: 43 SPDPCHGVTCRPQETCKEQGGQGVC--LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYV 100
SP TC +C GG C LP TC + G H ++D + +D G C+YV
Sbjct: 1054 SPGTSFNTTC---SSCTCSGGLWQCQDLP-CPGTCSVQGGAHISTYDEKLYDLHGDCSYV 1109
Query: 101 LATTGCLGVSTQGLTPFTVT--TKNENRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRV 158
L+ C S L T NEN ++ VT++ G + +I G V +
Sbjct: 1110 LSKK-CADSSFTVLAELRKCGLTDNEN-------CLKAVTLSLDGGDTAIRVQADGGVFL 1161
Query: 159 NGVLTALPVSVADGRISVAQGASKALLV-ADFGLQVSYDWN--WRVDVTLPSSYHGAVCG 215
N + T LP+S A+ I++ +S ++V GLQ+ +V V L ++ G +CG
Sbjct: 1162 NSIYTQLPLSAAN--ITLFTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLDPAHQGQMCG 1219
Query: 216 LCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYE 275
LCGN ++N +D +G + + + +W+A + C E+ E Y
Sbjct: 1220 LCGNFNQNQADDFTALSGVVEATGAAFANTWKAQAACANARNSFEDPCSLSVEN--ENY- 1276
Query: 276 GPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAA 335
+C L F+ CH+ + P+ F C+ D C D LC AL+SYV AC A
Sbjct: 1277 ARHWCSRLTDPNSA-FSRCHSIINPKPFHSNCMFDTCNCERSEDCLCAALSSYVHACAAK 1335
Query: 336 GVVIEDWRAQVGCEI--TCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDA 393
GV + DWR V + CP++ Y C +C + V+GC C A
Sbjct: 1336 GVQLSDWRDGVCTKYMQNCPKSQRYAYVVDACQPTCRGLSEADVTCSVSFVPVDGCTCPA 1395
Query: 394 G-FVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPAS--- 449
G F+ A CVP C C+A+GT G +G C GG L C AS
Sbjct: 1396 GTFLNDAGACVPAQE-CPCYAHGTVLAPGEVVHDEGAV-----CSCTGGKLSCLGASLQK 1449
Query: 450 ----------------------------------------CGLGEVC--GLLPSGQHGCQ 467
C G VC GL+ G GC
Sbjct: 1450 STGCAAPMVYLDCSNSSAGTPGAECLRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGCI 1509
Query: 468 PVSTAEC------------------------QAWGDPHYVTL--------------DGHR 489
C + W H + L DG R
Sbjct: 1510 AEEDCPCVHNEATYKPGETIRVDCNTCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDR 1569
Query: 490 FDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTL--------QIYNH 541
+ F+G+CEY+L+ G F + N G+ + ++++ L +
Sbjct: 1570 YSFEGSCEYILAQDYCGDNTTHGTFRIVTENIPCGTTGTTCSKAIKLFVEVRTAPAVSTP 1629
Query: 542 SLTLSARWPRKLQVDGVFVALPFQLDSLL--------HAHLSGAD----------VVVTT 583
+ PR+ V P Q L+ A G D +V
Sbjct: 1630 DPAANEPAPREASVGFRQRLPPLQSYELILQEGTFKAVARGPGGDPPYKIRYMGIFLVIE 1689
Query: 584 TSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCG 643
T G+++++D + V +R+ Y +CGLCGN++ + +D VG A G
Sbjct: 1690 THGMAVSWDRKTSVFIRLHQDYKGRVCGLCGNFDDNAINDFATRSRS----VVGDALEFG 1745
Query: 644 EC--VSKPCP------SPCTPEQQESFGGPDACGVISATDGP-LAPCHGLVPPAQYFQGC 694
+S CP PCT C ++ GP A C V +Y++ C
Sbjct: 1746 NSWKLSPSCPDALAPKDPCTANPFRKSWAQKQCSIL---HGPTFAACRSQVDSTKYYEAC 1802
Query: 695 LLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHS-------HY 745
+ DAC G C AVA Y AC AG + WR PD CPL C ++ HY
Sbjct: 1803 VNDACACDSGGDCECFCTAVAAYAQACHDAGLCV-SWRTPDTCPLFCDFYNPHGGCEWHY 1861
Query: 746 ELCGDSCPVSC--PS------LSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCL-H 796
+ CG C +C PS L EGC C + + D V QCGC
Sbjct: 1862 QPCGAPCLKTCRNPSGHCLVDLPGLEGCYPKCP-----PSQPFFNEDQMKCVAQCGCYDK 1916
Query: 797 DGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECR----------LEDGVQ 846
DG YY +G C+ C C P G AC E R DG+
Sbjct: 1917 DGNYYDVGARVPTAENCQ-SCNCTPSGIQCAHSLEACTCTYEDRTYSYQDVIYNTTDGLG 1975
Query: 847 ACHATGCGRCLANGGI 862
AC CG +NG I
Sbjct: 1976 ACLIAICG---SNGTI 1988
Score = 202 bits (513), Expect = 2e-51
Identities = 170/597 (28%), Positives = 241/597 (40%), Gaps = 79/597 (13%)
Query: 474 CQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-----SQAV 528
C WG HY T DG F F G C Y+ S C E+F + + S+ +
Sbjct: 81 CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGA---AYEDFNIQLRRSQESAAPTLSRVL 137
Query: 529 SYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLS 588
V +Q+ S+ V+G V LPF +L S + V GL
Sbjct: 138 MKVDGVVIQLTKGSVL----------VNGHPVLLPFSQSGVL-IQQSSSYTKVEARLGLV 186
Query: 589 LAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPA-DDLKAVGGKPAGWQVGGAQGCGECVS 647
L ++ D + L + YA CGLCG++N P +L + K + G Q + +
Sbjct: 187 LMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTPMEFGNLQKMDD-PT 245
Query: 648 KPCPSPCTPEQQESFGGPDACGVISATDGPL-APCHGLVPPAQYFQGCLLDACQVQGHP- 705
+ C P + G C + G L + C LV Y + C D C +
Sbjct: 246 EQCQDPVPEPPRNCSTGFGICEEL--LHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDL 303
Query: 706 -GGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEG 764
+C +A Y C AG +WR PDFCP +CP + Y C C +C +
Sbjct: 304 LSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEHSRA 363
Query: 765 CESACREGCVCDAGFVLS--GDT-CVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGP 821
CE C GC C G VL G T CVPV +C C+++G Y G + +C C C
Sbjct: 364 CEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATY--STDC-TNCTCS- 419
Query: 822 GGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCSYV 881
GG +CQE C G C GG H+ T DG+ Y +HG CSYV
Sbjct: 420 GGRWSCQE-VPCP-------------------GTCSVLGGAHFSTFDGKQYTVHGDCSYV 459
Query: 882 LAQVCHPKPGDEDFSIVLEKNAAG--DLQRLLVTV------AGQVVSLAQGQQVTVDGEA 933
L + C F+++ E G D + L +V A VV + +V ++
Sbjct: 460 LTKPC----DSSAFTVLAELRRCGLTDSETCLKSVTLSLDGAQTVVVIKASGEVFLNQIY 515
Query: 934 VALPVAVGRVRVTAEGRNMVL-QTTKGLRLLFD--GDAHLLMSIPSPFRGRLCGLCGNFN 990
LP++ V + ++ QT+ GL+L L M + RG+ CGLCGNFN
Sbjct: 516 TQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFN 575
Query: 991 GNWSDDFVLPNG----SAASSVETFGAAWRVPGSSKGCGEGCGPQGCPVCLAEETAP 1043
+DDF +G +AA+ TF P + C L+ E AP
Sbjct: 576 SIQADDFRTLSGVVEATAAAFFNTFKTQAACPNIRNSFEDPCS-------LSVENAP 625
Score = 185 bits (469), Expect = 3e-46
Identities = 153/557 (27%), Positives = 248/557 (44%), Gaps = 61/557 (10%)
Query: 845 VQACHATGCGR-CLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVL---E 900
V+A + GR C G HY T DG V+ G C+YV ++ C EDF+I L +
Sbjct: 69 VRASNPAHNGRVCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGA--AYEDFNIQLRRSQ 126
Query: 901 KNAAGDLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGL 960
++AA L R+L+ V G V+ L +G V V+G V LP + V + ++ GL
Sbjct: 127 ESAAPTLSRVLMKVDGVVIQLTKGS-VLVNGHPVLLPFSQSGVLIQQSSSYTKVEARLGL 185
Query: 961 RLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGS 1020
L+++ D LL+ + + + + CGLCG+FNG +L + + + +E FG ++
Sbjct: 186 VLMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTPME-FGNLQKMDDP 244
Query: 1021 SKGCGEGC--GPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVY 1078
++ C + P+ C C +L + Q F+ C A++ Y C
Sbjct: 245 TEQCQDPVPEPPRNCSTGFG----------ICEELLHGQ-LFSGCVALVDVGSYLEACRQ 293
Query: 1079 DLCAQKGDK--AFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQG 1136
DLC + + +C +LA Y+ C AG + WR FCP CP + Y C C
Sbjct: 294 DLCFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCAD 353
Query: 1137 SCAALSGLTGCTTRCFEGCECDDRFLL---SQGVCIPVQDCGCTHNG-RYLPVNSSLLTS 1192
+C+ C C GC C + +L Q C+PV C C +NG Y P + ++
Sbjct: 354 TCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAP--GATYST 411
Query: 1193 DCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGA 1252
DC+ C+CS +CQ CP G C + GA+ +TFDG +
Sbjct: 412 DCT-NCTCSGGR-WSCQEVPCP------------------GTCSVLGGAHFSTFDGKQYT 451
Query: 1253 TTSPGVYELSSRCPGLQNTIPWYRVVAEVQICH-GKTEAVGQVHIFFQDGMVTLTPNKG- 1310
Y L+ C + V+AE++ C +E + DG T+ K
Sbjct: 452 VHGDCSYVLTKPCDSSA-----FTVLAELRRCGLTDSETCLKSVTLSLDGAQTVVVIKAS 506
Query: 1311 --VWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQ--VWLGANGKVAVIVSNDHAG 1366
V++N + LP A+V++ R ++ + G+Q + L ++ + ++ G
Sbjct: 507 GEVFLNQIYTQLPI-SAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRG 565
Query: 1367 KLCGACGNFDGDQTNDW 1383
+ CG CGNF+ Q +D+
Sbjct: 566 QTCGLCGNFNSIQADDF 582
Score = 172 bits (436), Expect = 2e-42
Identities = 170/647 (26%), Positives = 257/647 (39%), Gaps = 80/647 (12%)
Query: 75 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLTPFTVTTKNENRGNPAVSYV 134
C WG HY +FDG F F G CNYV + G + + +++ P +S V
Sbjct: 81 CSTWGSFHYKTFDGDVFRFPGLCNYVFSEH--CGAAYEDFN--IQLRRSQESAAPTLSRV 136
Query: 135 RVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVS 194
+ G I + K G V VNG LP S + + + Q +S + A GL +
Sbjct: 137 ---LMKVDGVVIQLTK---GSVLVNGHPVLLPFSQSG--VLIQQSSSYTKVEARLGLVLM 188
Query: 195 YDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPL 254
++ + + + L + Y CGLCG+ + P ++ + T P+ G+ + DP
Sbjct: 189 WNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLT--PMEFGNLQKMD-DPT 245
Query: 255 CWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMG 314
++C+ P P + G G C L G F+ C A V S+ + C D+C
Sbjct: 246 --EQCQDPVPEPPRNCST---GFGICEELLHGQ--LFSGCVALVDVGSYLEACRQDLCFC 298
Query: 315 GGDHDIL---CKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPS 371
D D+L C LA Y C AG + +DWR C CP N Y C PC +C +
Sbjct: 299 E-DTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSN 357
Query: 372 PAPLTTPAVCEGPCVEGCQCDAGFVL---SADRCVPLNNGCGCWANGTYHEAGSEFWADG 428
CE CV GC C G VL CVP++ C C NG + G+ + D
Sbjct: 358 Q---EHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSK-CACVYNGAAYAPGATYSTD- 412
Query: 429 TCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPV-STAECQAWGDPHYVTLDG 487
CT +C G+ CQ V C G H+ T DG
Sbjct: 413 ----------------CTNCTCS---------GGRWSCQEVPCPGTCSVLGGAHFSTFDG 447
Query: 488 HRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTLQIYNHSLTLS 546
++ G C Y+L+ PC + FTV G + + + +SVTL + +
Sbjct: 448 KQYTVHGDCSYVLTKPC-----DSSAFTVLAELRRCGLTDSETCLKSVTLSLDGAQTVVV 502
Query: 547 ARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAA-- 604
+ ++ ++ ++ LP ++ S ++ T+ GL L ++L + A
Sbjct: 503 IKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPK 562
Query: 605 YAASLCGLCGNYNQDPADDLKAVGG-----KPAGWQVGGAQGCGECVSKPCPSPC--TPE 657
CGLCGN+N ADD + + G A + Q + PC + E
Sbjct: 563 LRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKTQAACPNIRNSFEDPCSLSVE 622
Query: 658 QQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGH 704
G P AC + LA LV P QG + + + GH
Sbjct: 623 NAPRMGAPSACRTL-----VLALAAMLVVPQAETQGPVEPSWENAGH 664
Score = 171 bits (432), Expect = 6e-42
Identities = 143/549 (26%), Positives = 238/549 (43%), Gaps = 70/549 (12%)
Query: 856 CLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGD---LQRLLV 912
C G HY T DG V+ G C+YV ++ C + EDF++ L + G + R+++
Sbjct: 733 CSTWGDFHYKTFDGDVFRFPGLCNYVFSEHC--RAAYEDFNVQLRRGLVGSRPVVTRVVI 790
Query: 913 TVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLM 972
G V+ + G V ++G+ LP + + V G + + L L++G+ L+
Sbjct: 791 KAQGLVLEASNGS-VLINGQREELPYSRTGLLVEQSGDYIKVSIRLVLTFLWNGEDSALL 849
Query: 973 SIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEGCGPQG 1032
+ + + CGLCG+FNG + + + + + ++ FG ++ G ++ C + P
Sbjct: 850 ELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLTPLQ-FGNLQKLDGPTEQCPDPL-PLP 907
Query: 1033 CPVCLAEETAPYESNEACGQLRNPQGP-FATCQAVLSPSEYFRQCVYDLCAQKGDKAFLC 1091
C EE + R GP FA C A++ + Y C DLC C
Sbjct: 908 AGNCTDEEGICH---------RTLLGPAFAECHALVDSTAYLAACAQDLCRCP---TCPC 955
Query: 1092 RSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRC 1151
+ Y+ C AG + WR CP CP + + C C +C+ C C
Sbjct: 956 ATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSNPQRAQLCEDHC 1015
Query: 1152 FEGCEC---------DDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSS 1202
+GC C DD ++ C+P+ C CTH GR +S T+ CS SC+
Sbjct: 1016 VDGCFCPPGRSCTVLDD---ITHSGCLPLGQCPCTHGGRTYSPGTSFNTT-CS---SCTC 1068
Query: 1203 SSGL-TCQAAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYEL 1261
S GL CQ CP G C + GA+++T+D Y L
Sbjct: 1069 SGGLWQCQDLPCP------------------GTCSVQGGAHISTYDEKLYDLHGDCSYVL 1110
Query: 1262 SSRCPGLQNTIPWYRVVAEVQICHGKTE---AVGQVHIFFQDG--MVTLTPNKGVWVNGL 1316
S +C T V+AE++ C G T+ + V + G + + + GV++N +
Sbjct: 1111 SKKCADSSFT-----VLAELRKC-GLTDNENCLKAVTLSLDGGDTAIRVQADGGVFLNSI 1164
Query: 1317 RVDLPAEKLASVSVSRTPDGSLLVRQKAGVQVWLGANGKVAVIVSND--HAGKLCGACGN 1374
LP A++++ ++V+ G+Q+ + + V V D H G++CG CGN
Sbjct: 1165 YTQLPLSA-ANITLFTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLDPAHQGQMCGLCGN 1223
Query: 1375 FDGDQTNDW 1383
F+ +Q +D+
Sbjct: 1224 FNQNQADDF 1232
Score = 125 bits (314), Expect = 3e-28
Identities = 123/461 (26%), Positives = 176/461 (38%), Gaps = 39/461 (8%)
Query: 39 LPLLSPDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCN 98
LP+ DP + C+ GG+G+ P C +WG HY +FDG + F+G C
Sbjct: 5376 LPIKVSDPSQPCDFHYECECECVGGRGIT-PG-AGICSMWGGSHYSTFDGTSYTFRGNCT 5433
Query: 99 YVL-----ATTGCLGVSTQG-LTPFTVTTKNENRGNPAVSYVRVVTVAALGTNISIHKDE 152
YVL A G L + + T P + ++ + T +H E
Sbjct: 5434 YVLMREIHARFGNLSLYLDNHYCTASATAAAAAARCPRALSIHYKSMDIVLTVTMVHGKE 5493
Query: 153 IGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRV-DVTLP-SSYH 210
G + + + + S +SV + + + G+ V++ N +V LP S +H
Sbjct: 5494 EGLILFDQIPVSSGFSKNGVLVSVLGTTTMRVDIPALGVSVTF--NGQVFQARLPYSLFH 5551
Query: 211 GAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAP-GWDPLCWDECRGSCPTC-PE 268
G CG N +D + +GT A S +W P CW G+ PT P
Sbjct: 5552 NNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTWLVPDSRKDGCWAP-TGTPPTASPA 5610
Query: 269 DRLEQYEGPGFCGP---LAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKAL 325
+ P C P F CH VPP FF C+ D C G ++ C++L
Sbjct: 5611 APVSSTPTPTPCPPQPLCDLMLSQVFAECHNLVPPGPFFNACISDHCR--GRLEVPCQSL 5668
Query: 326 ASYVAACQAAGVVIEDWRAQVG--CEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEG 383
+Y C+A G V DWR G C++TCP Y+ CGP PA+C S EG
Sbjct: 5669 EAYAELCRARG-VCSDWRGATGGLCDLTCPPTKVYKPCGPIQPATCNS---RNQSPQLEG 5724
Query: 384 PCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSL 443
EGC C +L C C + + E W Q C C G S+
Sbjct: 5725 -MAEGCFCPEDQILFNAHMGICVQACPCVGPDGFPKFPGERWVSN--CQSCVCDEGSVSV 5781
Query: 444 VCTPASCGL----------GEVCGLLPSGQHGCQPVSTAEC 474
C P C G V P ++ C P + C
Sbjct: 5782 QCKPLPCDAQGQPPPCNRPGFVTVTRPRAENPCCPETVCVC 5822
Score = 116 bits (290), Expect = 2e-25
Identities = 138/557 (24%), Positives = 187/557 (33%), Gaps = 89/557 (15%)
Query: 739 CPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCG----- 793
C H + +CP S P +S+ + GC D +P+ Q
Sbjct: 5295 CNQHCDIDRFQGACPTSPPPVSSAPLSSPSPAPGC----------DNAIPLRQVNETWTL 5344
Query: 794 -------CLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQ 846
C+ D R L P P C C H EC E
Sbjct: 5345 ENCTVARCVGDNRVVLLD----PKPVANVTCVNKHLPIKVSDPSQPCDFHYECECECVGG 5400
Query: 847 ACHATGCGRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPG------DEDFSIVLE 900
G G C GG HY T DG Y G+C+YVL + H + G D +
Sbjct: 5401 RGITPGAGICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTASA 5460
Query: 901 KNAAG---------------DLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRV 945
AA D+ + V G+ L Q+ V V V +
Sbjct: 5461 TAAAAAARCPRALSIHYKSMDIVLTVTMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGT 5520
Query: 946 TAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAA 1005
T ++ G+ + F+G S F G CG N DD + +G+ A
Sbjct: 5521 TTMRVDI---PALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTA 5577
Query: 1006 SSVETFGAAWRVPGSSK-GCGEGCG-----PQGCPVCLAEETAPYESNEACGQLRNPQGP 1059
+S + W VP S K GC G PV P C + +
Sbjct: 5578 ASCKDMAKTWLVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQPLCDLMLSQ--V 5635
Query: 1060 FATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWR--TDSFC 1117
FA C ++ P +F C+ D C +G C+SL AY C+A GV WR T C
Sbjct: 5636 FAECHNLVPPGPFFNACISDHC--RGRLEVPCQSLEAYAELCRARGVC-SDWRGATGGLC 5692
Query: 1118 PLHCPAHSHYSICTRTCQGSCAA------LSGLTGCTTRCFEGCEC-DDRFLLSQGVCIP 1170
L CP Y C +C + L G+ EGC C +D+ L + + I
Sbjct: 5693 DLTCPPTKVYKPCGPIQPATCNSRNQSPQLEGMA-------EGCFCPEDQILFNAHMGIC 5745
Query: 1171 VQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSS------GLTCQAAGCP-----PGRVC 1219
VQ C C + S+C + C C S L C A G P PG V
Sbjct: 5746 VQACPCVGPDGFPKFPGERWVSNC-QSCVCDEGSVSVQCKPLPCDAQGQPPPCNRPGFVT 5804
Query: 1220 EVKAEARNCWATRGLCV 1236
+ A N +CV
Sbjct: 5805 VTRPRAENPCCPETVCV 5821
Score = 94.7 bits (234), Expect = 5e-19
Identities = 131/572 (22%), Positives = 201/572 (35%), Gaps = 122/572 (21%)
Query: 322 CKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEV--CGPPCPASCP--SPAPLTT 377
C+A + + G VI + + GC N H ++ CP S P S APL++
Sbjct: 5267 CRAFGQFFSP----GEVIYNKTDRAGCHFYAVCNQHCDIDRFQGACPTSPPPVSSAPLSS 5322
Query: 378 PAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCG 437
P+ G D +PL +E W C+ RC
Sbjct: 5323 PSPAPG---------------CDNAIPLRQV-------------NETWTLENCTV-ARCV 5353
Query: 438 PGGGSLVCTPAS---------------------CGLGEVCGLLPSGQHGCQPVSTAECQA 476
++ P C C G G P C
Sbjct: 5354 GDNRVVLLDPKPVANVTCVNKHLPIKVSDPSQPCDFHYECECECVGGRGITP-GAGICSM 5412
Query: 477 WGDPHYVTLDGHRFDFQGTCEYLLSAPCHGP----PLGAENFTVTVANEHRGSQAVSYTR 532
WG HY T DG + F+G C Y+L H L +N T A+ + A R
Sbjct: 5413 WGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCT-ASATAAAAAARCPR 5471
Query: 533 SVTLQIYNHSLTLS-----ARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTS-G 586
++++ + + L+ + + D + V+ F + +L + L + V + G
Sbjct: 5472 ALSIHYKSMDIVLTVTMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMRVDIPALG 5531
Query: 587 LSLAFDGDSFVRLRVP-AAYAASLCGLCGNYNQDPADDLKAVGGKPAG--------WQVG 637
+S+ F+G F + R+P + + + G CG + DD G A W V
Sbjct: 5532 VSVTFNGQVF-QARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTWLVP 5590
Query: 638 GAQ--GC-------------GECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCH 682
++ GC S P P+PC P+ C ++ + A CH
Sbjct: 5591 DSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQ--------PLCDLMLSQ--VFAECH 5640
Query: 683 GLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWR--RPDFCPLQCP 740
LVPP +F C+ D C +G C ++ Y C+A G +WR C L CP
Sbjct: 5641 NLVPPGPFFNACISDHC--RGRLEVPCQSLEAYAELCRARGV-CSDWRGATGGLCDLTCP 5697
Query: 741 AHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVL-SGDTCVPVGQCGCLHDGR 799
Y+ CG P +C S + E EGC C +L + + V C C+
Sbjct: 5698 PTKVYKPCGPIQPATCNSRNQSPQLEGMA-EGCFCPEDQILFNAHMGICVQACPCVG--- 5753
Query: 800 YYPLGEVFYPGPECERRCECGPGGHVTCQEGA 831
P G +PG C+ C EG+
Sbjct: 5754 --PDGFPKFPGERWVSNCQ-----SCVCDEGS 5778
Score = 57.0 bits (136), Expect = 1e-07
Identities = 56/227 (24%), Positives = 97/227 (42%), Gaps = 30/227 (13%)
Query: 6 CGLACSNPQ------IPGTDWVDMEGAAMLYNGQPLKVLLPLLSPDPCHGVTCRPQETCK 59
C C P+ I T V + A +YNG +P + C C
Sbjct: 368 CVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAY-------APGATYSTDCT---NCT 417
Query: 60 EQGGQGVCLP-NYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLTPFT 118
GG+ C TC + G H+ +FDG+++ G C+YVL T C + FT
Sbjct: 418 CSGGRWSCQEVPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVL-TKPC------DSSAFT 470
Query: 119 VTTKNENRG-NPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVA 177
V + G + + ++ VT++ G + G+V +N + T LP+S A+ +++
Sbjct: 471 VLAELRRCGLTDSETCLKSVTLSLDGAQTVVVIKASGEVFLNQIYTQLPISAAN--VTIF 528
Query: 178 QGASKALLV-ADFGLQVSYDW--NWRVDVTLPSSYHGAVCGLCGNMD 221
+ ++ ++ GLQ++ ++ + L G CGLCGN +
Sbjct: 529 RPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFN 575
Score = 56.2 bits (134), Expect = 2e-07
Identities = 70/281 (24%), Positives = 98/281 (34%), Gaps = 55/281 (19%)
Query: 1134 CQGSCAALSGLTGC-TTRCFEGCECDDRFLLS-QGVCIPVQDCGCTHN-GRYLPVNSSLL 1190
C SC L GC +T C GC C + G CI +DC C HN Y P +
Sbjct: 1474 CLRSCHTLD--VGCFSTHCVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKP--GETI 1529
Query: 1191 TSDCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGAR 1250
DC+ C+C + C C G CV + TFDG R
Sbjct: 1530 RVDCN-TCTCRNRR-WECSHRLC------------------LGTCVAYGDGHFITFDGDR 1569
Query: 1251 GATTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGK-TEAVGQVHIFFQDGMVTLTPNK 1309
+ Y L+ G T +R+V E C T + +F +
Sbjct: 1570 YSFEGSCEYILAQDYCGDNTTHGTFRIVTENIPCGTTGTTCSKAIKLFVEVRTAPAVSTP 1629
Query: 1310 GVWVN---------GLRVDLP--------AEKLASVSVSRTPDGS----------LLVRQ 1342
N G R LP ++ +V+R P G LV +
Sbjct: 1630 DPAANEPAPREASVGFRQRLPPLQSYELILQEGTFKAVARGPGGDPPYKIRYMGIFLVIE 1689
Query: 1343 KAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTNDW 1383
G+ V V + + D+ G++CG CGNFD + ND+
Sbjct: 1690 THGMAVSWDRKTSVFIRLHQDYKGRVCGLCGNFDDNAINDF 1730
Score = 35.8 bits (81), Expect = 0.30
Identities = 50/202 (24%), Positives = 66/202 (32%), Gaps = 54/202 (26%)
Query: 602 PAAYAASLCGLCGNYNQDPA----DDLKAVGGKPAGWQVGGAQG--CGECVSKPCPSP-- 653
P A +C QDP +D P G++ G CGECV C +P
Sbjct: 5874 PGALPCHMCTCLSGDTQDPTVQCQEDACNNTTCPQGFEYKRVAGQCCGECVQTACLTPDG 5933
Query: 654 ----------------CTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLD 697
CT E+ GG A+ ++ C G + C D
Sbjct: 5934 QPVQLNETWVNSHVDNCTVYLCEAEGGVHLLTPQPASCPDVSSCRGSLRKTGCCYSCEED 5993
Query: 698 ACQVQ------GHPG-----------GLCPAVATYVAACQAAGAQLG--EWRR--PDFCP 736
+CQV+ H G G CP + Y A QA Q + RR + P
Sbjct: 5994 SCQVRINTTILWHQGCETEVNITFCEGSCPGASKYSAEAQAMQHQCTCCQERRVHEETVP 6053
Query: 737 LQCP---------AHSHYELCG 749
L CP H+ LCG
Sbjct: 6054 LHCPNGSAILHTYTHAVQVLCG 6075
>gi|89191868 von Willebrand factor preproprotein [Homo sapiens]
Length = 2813
Score = 308 bits (790), Expect = 2e-83
Identities = 277/1047 (26%), Positives = 390/1047 (37%), Gaps = 205/1047 (19%)
Query: 470 STAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVS 529
STA C +G T DG + F G C YLL+ C +F++ + + G +
Sbjct: 31 STARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQ-----KRSFSI-IGDFQNGKR--- 81
Query: 530 YTRSVTLQIYNHSLTLSARWPRKLQVDGVF------VALPFQLDSLLHAHLSGADVVVTT 583
V+L +Y L + L V+G V++P+ L +G +
Sbjct: 82 ----VSLSVY-----LGEFFDIHLFVNGTVTQGDQRVSMPYASKGLYLETEAGYYKLSGE 132
Query: 584 TSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAG--------WQ 635
G DG ++ + Y CGLCGN+N DD G W
Sbjct: 133 AYGFVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWA 192
Query: 636 VGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCL 695
+ + E S P S + G + C ++ +T A CH LV P + C
Sbjct: 193 LSSGEQWCERASPPSSSCNISSGEMQKGLWEQCQLLKSTS-VFARCHPLVDPEPFVALCE 251
Query: 696 LDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVS 755
C+ G CPA+ Y C G L W C CPA Y C C +
Sbjct: 252 KTLCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCART 311
Query: 756 CPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECER 815
C SL E C+ C +GC C G +L CV +C C+H G+ YP PG R
Sbjct: 312 CQSLHINEMCQERCVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYP------PGTSLSR 365
Query: 816 RCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLH 875
C C+ +EEC G CL G H+ + D R +
Sbjct: 366 DCNT-----CICRNSQWICSNEECP-------------GECLVTGQSHFKSFDNRYFTFS 407
Query: 876 GSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRLLVT---------VAGQVVSLAQGQQ 926
G C Y+LA+ C D FSIV+E D + + T + +V L G
Sbjct: 408 GICQYLLARDCQ----DHSFSIVIETVQCADDRDAVCTRSVTVRLPGLHNSLVKLKHGAG 463
Query: 927 VTVDGEAVALPVAVGRVR----VTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRL 982
V +DG+ V LP+ G +R VTA R L + L++ +DG LL+ + + G+
Sbjct: 464 VAMDGQDVQLPLLKGDLRIQHTVTASVR---LSYGEDLQMDWDGRGRLLVKLSPVYAGKT 520
Query: 983 CGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEGCGPQGCPVCLAEETA 1042
CGLCGN+NGN DDF+ P+G A VE FG AW++ G + + Q C
Sbjct: 521 CGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLHGDCQDLQK----QHSDPCALNPRM 576
Query: 1043 PYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQ 1102
S EAC L +P F C +SP Y R C YD+C+ + LC +LA+Y AAC
Sbjct: 577 TRFSEEACAVLTSPT--FEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALASYAAACA 634
Query: 1103 AAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTG-CTTRCFEGCECDDRF 1161
GV V WR C L+CP Y C C +C +LS C C EGC C
Sbjct: 635 GRGVRVA-WREPGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECNEACLEGCFCPPGL 693
Query: 1162 LLSQ-GVCIPVQDCGCTHN--------------------------------GRYLPVNSS 1188
+ + G C+P C C ++ G LP +
Sbjct: 694 YMDERGDCVPKAQCPCYYDGEIFQPEDIFSDHHTMCYCEDGFMHCTMSGVPGSLLP--DA 751
Query: 1189 LLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWAT---RGLCVLSVGANLTT 1245
+L+S S R S S CP + +AE C T L +S+G
Sbjct: 752 VLSSPLSHRSKRSLSCRPPMVKLVCPADNL---RAEGLECTKTCQNYDLECMSMGC---- 804
Query: 1246 FDGARGATTSPGVYELSSRCPGLQNTIPWYRVVAEV------------------------ 1281
G PG+ +RC L+ P + E
Sbjct: 805 ---VSGCLCPPGMVRHENRCVALERC-PCFHQGKEYAPGETVKIGCNTCVCRDRKWNCTD 860
Query: 1282 QICHGKTEAVGQVHIFFQDGMVTLTP------------------------NKG------- 1310
+C +G H DG+ L P NKG
Sbjct: 861 HVCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRILVGNKGCSHPSVK 920
Query: 1311 ------VWVNGLRVDL---------PAEKLASVSVSRTPDGSLLVRQKAGVQVWLGANGK 1355
+ V G ++L P + V + +L+ KA VW +
Sbjct: 921 CKKRVTILVEGGEIELFDGEVNVKRPMKDETHFEVVESGRYIILLLGKALSVVW-DRHLS 979
Query: 1356 VAVIVSNDHAGKLCGACGNFDGDQTND 1382
++V++ + K+CG CGNFDG Q ND
Sbjct: 980 ISVVLKQTYQEKVCGLCGNFDGIQNND 1006
Score = 276 bits (706), Expect = 1e-73
Identities = 219/764 (28%), Positives = 302/764 (39%), Gaps = 76/764 (9%)
Query: 73 ATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLTPFTVTTKNENRGNPAVS 132
A C L+G ++FDG + F G C+Y+LA GC S F++ +N ++S
Sbjct: 33 ARCSLFGSDFVNTFDGSMYSFAGYCSYLLAG-GCQKRS------FSIIGDFQNGKRVSLS 85
Query: 133 YVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQ 192
LG IH G V ++P + + G K L +G
Sbjct: 86 VY-------LGEFFDIHLFVNGTVTQGDQRVSMPYASKGLYLETEAGYYK-LSGEAYGFV 137
Query: 193 VSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWD 252
D + V L Y CGLCGN + +D + GTL + SW +
Sbjct: 138 ARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGE 197
Query: 253 PLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVC 312
C + +C E +G L T F CH V PE F C +C
Sbjct: 198 QWC-ERASPPSSSCNISSGEMQKGLWEQCQLLKSTS-VFARCHPLVDPEPFVALCEKTLC 255
Query: 313 MGGGDHDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSP 372
G + C AL Y C G+V+ W C CP Y C PC +C S
Sbjct: 256 ECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQS- 314
Query: 373 APLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWAD-GTC- 430
L +C+ CV+GC C G +L CV + C C +G + G+ D TC
Sbjct: 315 --LHINEMCQERCVDGCSCPEGQLLDEGLCVE-STECPCVHSGKRYPPGTSLSRDCNTCI 371
Query: 431 ---SQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDG 487
SQW +C+ C EC G H+ + D
Sbjct: 372 CRNSQW----------ICSNEEC--------------------PGECLVTGQSHFKSFDN 401
Query: 488 HRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYN-HSLTLS 546
F F G C+YLL+ C TV A++ AV TRSVT+++ H+ +
Sbjct: 402 RYFTFSGICQYLLARDCQDHSFSIVIETVQCADDR---DAVC-TRSVTVRLPGLHNSLVK 457
Query: 547 ARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYA 606
+ + +DG V LP L H A V ++ L + +DG + +++ YA
Sbjct: 458 LKHGAGVAMDGQDVQLPLLKGDLRIQHTVTASVRLSYGEDLQMDWDGRGRLLVKLSPVYA 517
Query: 607 ASLCGLCGNYNQDPADDLKAVGG--KPAGWQVGGAQGC-GEC--VSKPCPSPCTPEQQES 661
CGLCGNYN + DD G +P G A G+C + K PC + +
Sbjct: 518 GKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLHGDCQDLQKQHSDPCALNPRMT 577
Query: 662 FGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQA 721
+AC V+ T CH V P Y + C D C LC A+A+Y AAC
Sbjct: 578 RFSEEACAVL--TSPTFEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALASYAAACAG 635
Query: 722 AGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAP-EGCESACREGCVCDAGFV 780
G ++ WR P C L CP Y CG C ++C SLS P E C AC EGC C G
Sbjct: 636 RGVRVA-WREPGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECNEACLEGCFCPPGLY 694
Query: 781 LS--GDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPG 822
+ GD CVP QC C +DG + ++F + C C G
Sbjct: 695 MDERGD-CVPKAQCPCYYDGEIFQPEDIF---SDHHTMCYCEDG 734
Score = 177 bits (449), Expect = 6e-44
Identities = 144/542 (26%), Positives = 217/542 (40%), Gaps = 53/542 (9%)
Query: 855 RCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQR----L 910
RC G T DG +Y G CSY+LA C + FSI+ GD Q
Sbjct: 34 RCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKR----SFSII------GDFQNGKRVS 83
Query: 911 LVTVAGQV--VSLAQGQQVTVDGEAVALPVAV-GRVRVTAEGRNMVLQTTKGLRLLFDGD 967
L G+ + L VT + V++P A G T G + G DG
Sbjct: 84 LSVYLGEFFDIHLFVNGTVTQGDQRVSMPYASKGLYLETEAGYYKLSGEAYGFVARIDGS 143
Query: 968 AHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEG 1027
+ + + + + CGLCGNFN DDF+ G+ S F +W + + C
Sbjct: 144 GNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQWCERA 203
Query: 1028 CGPQG-CPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGD 1086
P C + E E C QL FA C ++ P + C LC G
Sbjct: 204 SPPSSSCNISSGEMQKGLW--EQC-QLLKSTSVFARCHPLVDPEPFVALCEKTLCECAGG 260
Query: 1087 KAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTG 1146
C +L Y C G+ + W S C CPA Y C C +C +L
Sbjct: 261 LECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQSLHINEM 320
Query: 1147 CTTRCFEGCECDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGL 1206
C RC +GC C + LL +G+C+ +C C H+G+ P +S L+ DC+ C C +S +
Sbjct: 321 CQERCVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYPPGTS-LSRDCN-TCICRNSQWI 378
Query: 1207 TCQAAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCP 1266
C CP G C+++ ++ +FD + Y L+ C
Sbjct: 379 -CSNEECP------------------GECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQ 419
Query: 1267 GLQNTIPWYRVVAEVQICHGKTEAVGQVHIF-----FQDGMVTLTPNKGVWVNGLRVDLP 1321
+ +V E C +AV + + +V L GV ++G V LP
Sbjct: 420 DHS-----FSIVIETVQCADDRDAVCTRSVTVRLPGLHNSLVKLKHGAGVAMDGQDVQLP 474
Query: 1322 AEKLASVSVSRTPDGSLLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTN 1381
K + + T S+ + +Q+ G++ V +S +AGK CG CGN++G+Q +
Sbjct: 475 LLK-GDLRIQHTVTASVRLSYGEDLQMDWDGRGRLLVKLSPVYAGKTCGLCGNYNGNQGD 533
Query: 1382 DW 1383
D+
Sbjct: 534 DF 535
Score = 154 bits (390), Expect = 4e-37
Identities = 150/550 (27%), Positives = 211/550 (38%), Gaps = 73/550 (13%)
Query: 699 CQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPS 758
C + G PG L P + L RP L CPA + G C +C +
Sbjct: 738 CTMSGVPGSLLPDAVLSSPLSHRSKRSLS--CRPPMVKLVCPA-DNLRAEGLECTKTCQN 794
Query: 759 LSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCE 818
E C GC+C G V + CV + +C C H G+ Y GE G C C
Sbjct: 795 YDL-ECMSMGCVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGETVKIG--CNT-CV 850
Query: 819 CGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSC 878
C C H C AT C G HY+T DG Y G C
Sbjct: 851 CR-------DRKWNCTDH----------VCDAT----CSTIGMAHYLTFDGLKYLFPGEC 889
Query: 879 SYVLAQ-VCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVSLAQGQQVTV-DGEA-VA 935
YVL Q C PG F I++ V +V L +G ++ + DGE V
Sbjct: 890 QYVLVQDYCGSNPGT--FRILVGNKGCSHPS---VKCKKRVTILVEGGEIELFDGEVNVK 944
Query: 936 LPVA-VGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWS 994
P+ V GR ++L K L +++D + + + ++ ++CGLCGNF+G +
Sbjct: 945 RPMKDETHFEVVESGRYIILLLGKALSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQN 1004
Query: 995 DDFVLPNGSAASSVETFGAAWRVPGSSKGCGE------GCGPQGCPVCLAEETAPYESNE 1048
+D N FG +W+V S C + P C + ++T +
Sbjct: 1005 NDLTSSNLQVEEDPVDFGNSWKV---SSQCADTRKVPLDSSPATCHNNIMKQTM---VDS 1058
Query: 1049 ACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQK--GDKAFLCRSLAAYTAACQAAGV 1106
+C L + F C ++ P Y C+YD C+ + GD A C ++AAY C G
Sbjct: 1059 SCRILTS--DVFQDCNKLVDPEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVCAQHGK 1116
Query: 1107 AVKPWRTDSFCPLHCPAHS----------HYSICTRTCQGSCAALSGLTGCTTRCFEGC- 1155
V WRT + CP C + Y+ C CQ +C L C +C EGC
Sbjct: 1117 VV-TWRTATLCPQSCEERNLRENGYECEWRYNSCAPACQVTCQHPEPL-ACPVQCVEGCH 1174
Query: 1156 -ECDDRFLLSQ--GVCIPVQDCG-CTHNGRYLPVNSSL-LTSDCSERCSCSSSS--GLTC 1208
C +L + C+ +DC C GR + L E C LTC
Sbjct: 1175 AHCPPGKILDELLQTCVDPEDCPVCEVAGRRFASGKKVTLNPSDPEHCQICHCDVVNLTC 1234
Query: 1209 QAAGCPPGRV 1218
+A P G V
Sbjct: 1235 EACQEPGGLV 1244
Score = 134 bits (336), Expect = 8e-31
Identities = 119/462 (25%), Positives = 184/462 (39%), Gaps = 60/462 (12%)
Query: 797 DGRYYPLGEVFYPGPECERRCECGPGGH-------VTCQEGA--ACGPHEECRLEDGVQA 847
DG G+V+ +C C P G V C G +C + +
Sbjct: 1883 DGNEKRPGDVWTLPDQCHT-VTCQPDGQTLLKSHRVNCDRGLRPSCPNSQSPVKVEETCG 1941
Query: 848 CHATGCGRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAA--- 904
C T C + H +T DG+ + L GSCSYVL Q ++D ++L A
Sbjct: 1942 CRWTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQ-----NKEQDLEVILHNGACSPG 1996
Query: 905 ---GDLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLR 961
G ++ + V + V L +VTV+G V++P G + V G M L
Sbjct: 1997 ARQGCMKSIEVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLG 2056
Query: 962 LLF----DGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRV 1017
+F + L P F + GLCG + N ++DF+L +G+ + +T W V
Sbjct: 2057 HIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTV 2116
Query: 1018 PGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCV 1077
+ G+ C P + EE + C L P FA C VL+P+ ++ C
Sbjct: 2117 ----QRPGQTCQP------ILEEQCLVPDSSHCQVLLLPL--FAECHKVLAPATFYAICQ 2164
Query: 1078 YDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGS 1137
D C Q+ +C +A+Y C+ GV V WRT FC + CP Y+ C C
Sbjct: 2165 QDSCHQEQ----VCEVIASYAHLCRTNGVCV-DWRTPDFCAMSCPPSLVYNHCEHGCPRH 2219
Query: 1138 CAALSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQDC-------GCTHNGRYLPVNSSLL 1190
C ++ C EGC C ++ +G C+P + C G H + + +
Sbjct: 2220 CD--GNVSSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQF----LEAWVP 2273
Query: 1191 TSDCSERCSCSSSSGLTCQAAGCPPGR-----VCEVKAEARN 1227
+ C+C S + C CP + +CEV +N
Sbjct: 2274 DHQPCQICTCLSGRKVNCTTQPCPTAKAPTCGLCEVARLRQN 2315
Score = 128 bits (321), Expect = 4e-29
Identities = 115/416 (27%), Positives = 160/416 (38%), Gaps = 60/416 (14%)
Query: 47 CHGVTCRPQE-TCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTG 105
C+ CR ++ C + VC +ATC G HY +FDG K+ F G C YVL
Sbjct: 846 CNTCVCRDRKWNCTDH----VC----DATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDY 897
Query: 106 CLGVSTQGLTP--FTVTTKNENRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLT 163
C G P F + N+ +P+V + VT+ G I + E+ R
Sbjct: 898 C------GSNPGTFRILVGNKGCSHPSVKCKKRVTILVEGGEIELFDGEVNVKR------ 945
Query: 164 ALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRN 223
P+ + V + +L+ L V +D + + V L +Y VCGLCGN D
Sbjct: 946 --PMK-DETHFEVVESGRYIILLLGKALSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGI 1002
Query: 224 PNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECR----GSCPTCPEDRLEQYEGPGF 279
NND N + +G SW+ C D + S TC + ++Q
Sbjct: 1003 QNNDLTSSNLQVEEDPVDFGNSWKV---SSQCADTRKVPLDSSPATCHNNIMKQTMVDSS 1059
Query: 280 CGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCM--GGGDHDILCKALASYVAACQAAGV 337
C L T F C+ V PE + C+ D C GD C +A+Y C G
Sbjct: 1060 CRIL---TSDVFQDCNKLVDPEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVCAQHGK 1116
Query: 338 VIEDWRAQVGCEITCPENS----------HYEVCGPPCPASCPSPAPLTTPAVCEGPCVE 387
V+ WR C +C E + Y C P C +C P PL P CVE
Sbjct: 1117 VV-TWRTATLCPQSCEERNLRENGYECEWRYNSCAPACQVTCQHPEPLACPV----QCVE 1171
Query: 388 GC--QCDAGFVLS--ADRCVPLNNGCGCWANGTYHEAGSEFW---ADGTCSQWCRC 436
GC C G +L CV + C G +G + +D Q C C
Sbjct: 1172 GCHAHCPPGKILDELLQTCVDPEDCPVCEVAGRRFASGKKVTLNPSDPEHCQICHC 1227
Score = 115 bits (288), Expect = 3e-25
Identities = 124/500 (24%), Positives = 180/500 (36%), Gaps = 85/500 (17%)
Query: 361 CGPP-----CPASCPSPAPLTTPAVCEG--------PCVEGCQCDAGFVLSADRCVPLNN 407
C PP CPA L C+ CV GC C G V +RCV L
Sbjct: 767 CRPPMVKLVCPADNLRAEGLECTKTCQNYDLECMSMGCVSGCLCPPGMVRHENRCVALER 826
Query: 408 GCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQ 467
C C +H+ G E+ T C + VC + H C
Sbjct: 827 -CPC-----FHQ-GKEYAPGETVKIGCN------TCVCRDRKWNCTD---------HVCD 864
Query: 468 PVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQA 527
A C G HY+T DG ++ F G C+Y+L G G F + V N+ +
Sbjct: 865 ----ATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPG--TFRILVGNKGCSHPS 918
Query: 528 VSYTRSVTLQIYNHSLTLSARWPRKLQVDG-VFVALPFQLDSLLHAHLSGADVVVTTTSG 586
V + VT+ + + L DG V V P + ++ SG +++
Sbjct: 919 VKCKKRVTILVEGGEIEL---------FDGEVNVKRPMKDETHFEVVESGRYIILLLGKA 969
Query: 587 LSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKA----VGGKPA----GWQVGG 638
LS+ +D + + + Y +CGLCGN++ +DL + V P W+V
Sbjct: 970 LSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKV-- 1027
Query: 639 AQGCGECVSKP---CPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCL 695
+ C + P P+ C + +C ++ T C+ LV P Y C+
Sbjct: 1028 SSQCADTRKVPLDSSPATCHNNIMKQTMVDSSCRIL--TSDVFQDCNKLVDPEPYLDVCI 1085
Query: 696 LDACQVQ--GHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHS---------- 743
D C + G C +A Y C G ++ WR CP C +
Sbjct: 1086 YDTCSCESIGDCACFCDTIAAYAHVCAQHG-KVVTWRTATLCPQSCEERNLRENGYECEW 1144
Query: 744 HYELCGDSCPVSCPSLSAPEGCESACREGC--VCDAGFVLSG--DTCVPVGQCG-CLHDG 798
Y C +C V+C P C C EGC C G +L TCV C C G
Sbjct: 1145 RYNSCAPACQVTCQH-PEPLACPVQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCEVAG 1203
Query: 799 RYYPLGEVFYPGPECERRCE 818
R + G+ P C+
Sbjct: 1204 RRFASGKKVTLNPSDPEHCQ 1223
Score = 108 bits (271), Expect = 3e-23
Identities = 101/405 (24%), Positives = 162/405 (40%), Gaps = 47/405 (11%)
Query: 465 GCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG 524
GC+ C H VT DG F G+C Y+L E + +
Sbjct: 1941 GCRWTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQ-------NKEQDLEVILHNGAC 1993
Query: 525 SQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTT 584
S ++++ + +L++ ++ V+G V++P+ + + ++ GA +
Sbjct: 1994 SPGARQGCMKSIEVKHSALSVELHSDMEVTVNGRLVSVPY-VGGNMEVNVYGAIMHEVRF 2052
Query: 585 SGLSLAF----DGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGK-PAGWQVGGA 639
+ L F + F P +A+ GLCG +++ A+D G W+
Sbjct: 2053 NHLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQ 2112
Query: 640 QGCGECVSKPCPSPCTPEQQESFGGPDA--CGVISATDGPL-APCHGLVPPAQYFQGCLL 696
+ V +P + C P +E PD+ C V+ PL A CH ++ PA ++ C
Sbjct: 2113 EWT---VQRPGQT-CQPILEEQCLVPDSSHCQVLLL---PLFAECHKVLAPATFYAICQQ 2165
Query: 697 DACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSC 756
D+C H +C +A+Y C+ G + +WR PDFC + CP Y C CP C
Sbjct: 2166 DSC----HQEQVCEVIASYAHLCRTNGVCV-DWRTPDFCAMSCPPSLVYNHCEHGCPRHC 2220
Query: 757 PSLSAPEGCESAC----REGCVCDAGFVLSGDTCVPVGQC-GCL-HDGRYYPLGEVFYPG 810
+G S+C EGC C V+ +CVP C C+ DG + E + P
Sbjct: 2221 ------DGNVSSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPD 2274
Query: 811 PECERRCECGPGGHVTC-------QEGAACGPHEECRLEDGVQAC 848
+ + C C G V C + CG E RL C
Sbjct: 2275 HQPCQICTCLSGRKVNCTTQPCPTAKAPTCGLCEVARLRQNADQC 2319
Score = 93.6 bits (231), Expect = 1e-18
Identities = 115/469 (24%), Positives = 166/469 (35%), Gaps = 75/469 (15%)
Query: 44 PDPCHGVTCRP--QETCK------EQGGQGVCLPN------YEATCWL-WGDP------- 81
PD CH VTC+P Q K ++G + C PN E TC W P
Sbjct: 1896 PDQCHTVTCQPDGQTLLKSHRVNCDRGLRPSC-PNSQSPVKVEETCGCRWTCPCVCTGSS 1954
Query: 82 --HYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLTPFTVTTKNENRGNPAVSYVRVVTV 139
H +FDG+ F G+C+YVL Q L + ++ + V
Sbjct: 1955 TRHIVTFDGQNFKLTGSCSYVLFQN-----KEQDLE--VILHNGACSPGARQGCMKSIEV 2007
Query: 140 AALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSY-DWN 198
++ +H D +V VNG L ++P + ++V + G ++ N
Sbjct: 2008 KHSALSVELHSDM--EVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLGHIFTFTPQN 2065
Query: 199 WRVDVTL-PSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWD 257
+ L P ++ GLCG D N ND + +GT+ W C
Sbjct: 2066 NEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQRPGQTCQP 2125
Query: 258 ECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGD 317
C + P F CH + P +F+ C D C
Sbjct: 2126 ILEEQCLVPDSSHCQVLLLP------------LFAECHKVLAPATFYAICQQDSC----H 2169
Query: 318 HDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTT 377
+ +C+ +ASY C+ GV + DWR C ++CP + Y C CP C
Sbjct: 2170 QEQVCEVIASYAHLCRTNGVCV-DWRTPDFCAMSCPPSLVYNHCEHGCPRHCDG-----N 2223
Query: 378 PAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGC-WANGTYHEAGSEFWADGTCSQWCRC 436
+ C EGC C V+ CVP C +G H+ + D Q C C
Sbjct: 2224 VSSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPDHQPCQICTC 2283
Query: 437 GPGGGSLVCT--------PASCGLGEVCGL-------LPSGQHGCQPVS 470
G + CT +CGL EV L P + C PVS
Sbjct: 2284 -LSGRKVNCTTQPCPTAKAPTCGLCEVARLRQNADQCCPEYECVCDPVS 2331
Score = 32.0 bits (71), Expect = 4.3
Identities = 49/178 (27%), Positives = 62/178 (34%), Gaps = 40/178 (22%)
Query: 694 CLLDACQV-QGHPGGLCPAVATYVAACQAAGAQLGEWRRPDF-CPLQCPAHSHYELCGDS 751
CL AC+V G P G ++ ++ G+Q W P+ C + E+
Sbjct: 2494 CLPSACEVVTGSPRG------DSQSSWKSVGSQ---WASPENPCLINECVRVKEEVFIQQ 2544
Query: 752 CPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGP 811
VSCP L P VC +GF LS T C C G V PG
Sbjct: 2545 RNVSCPQLEVP-----------VCPSGFQLSCKTSACCPSCRCERMEACMLNGTVIGPGK 2593
Query: 812 ----ECERRCECGPGGHVTCQEGAACGPHEECRLED------GVQACHATG--CGRCL 857
+ C C Q G G ECR G + + TG CGRCL
Sbjct: 2594 TVMIDVCTTCRC------MVQVGVISGFKLECRKTTCNPCPLGYKEENNTGECCGRCL 2645
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 304 bits (779), Expect = 3e-82
Identities = 310/1265 (24%), Positives = 480/1265 (37%), Gaps = 209/1265 (16%)
Query: 75 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLTPFTVTTKNENRGNPAVSYV 134
C WG+ HY +FDG F F G C+Y A+ C G + F V K A + V
Sbjct: 37 CSTWGNFHYKTFDGDVFRFPGLCDYNFASD-CRGSYKE----FAVHLKRGPGQAEAPAGV 91
Query: 135 RVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVA--DGRISVAQGASKALLVADFGLQ 192
+ ++I D I R VL VS + + + + + + GL
Sbjct: 92 ESIL-------LTIKDDTIYLTRHLAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLT 144
Query: 193 VSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWD 252
+ ++ + + L + + CGLCG+ + + + +G L + +G + D
Sbjct: 145 LMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLE-FGNMQKINQPD 203
Query: 253 PLCWDECRGSCP-TCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV 311
+C D P +C E R E C L T F C VP E + + C D
Sbjct: 204 VVCEDPEEEVAPASCSEHRAE-------CERLL--TAEAFADCQDLVPLEPYLRACQQDR 254
Query: 312 CMGGGDHDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPS 371
C G +C +A + C AG +WR C TCP N Y G PC +C
Sbjct: 255 CRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATLCPKTCPGNLVYLESGSPCMDTC-- 312
Query: 372 PAPLTTPAVCEGPCVEGCQCDAGFV---LSADRCVPLNNGCGCWANGTYHEAGSEFWADG 428
+ L ++CE ++GC C G V + CVP++ C C +G + G E D
Sbjct: 313 -SHLEVSSLCEEHRMDGCFCPEGTVYDDIGDSGCVPVSQ-CHCRLHGHLYTPGQEITND- 369
Query: 429 TCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGH 488
C Q C C G VC C C G H T DG
Sbjct: 370 -CEQ-CVC--NAGRWVCKDLPC--------------------PGTCALEGGSHITTFDGK 405
Query: 489 RFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGS-QAVSYTRSVTLQIYNHSLTLSA 547
+ F G C Y+L+ H +++ + GS + ++V L +
Sbjct: 406 TYTFHGDCYYVLAKGDHN-----DSYALLGELAPCGSTDKQTCLKTVVLLADKKKNVVVF 460
Query: 548 RWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAA 607
+ + ++ + V LP S S ++V+ G+ L ++L V A+
Sbjct: 461 KSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQAS 520
Query: 608 --SLCGLCGNYNQDPADDLKAVGGKPAGWQVGGA---QGCGECVSKP--CPSPCTPEQQE 660
+ GLCGN+N DD K G G A + C K PC+ +
Sbjct: 521 QGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKLDWLDDPCSLNIES 580
Query: 661 SFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQ 720
+ C ++ T+ P CH V PA+Y++ C D C Q + LC A+++Y AC
Sbjct: 581 ANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACT 640
Query: 721 AAGAQLGEWRRPDFCPL---QCPAHSHYELCGDSCPVSCPSLSAPEGCESACRE------ 771
A G L WR C CP + +C +C SLS +S C E
Sbjct: 641 AKGVMLWGWRE-HVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSE---ADSHCLEGFAPVD 696
Query: 772 GCVC-DAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPG-------- 822
GC C D F+ CVP+ +C C H G Y G+V E RC C G
Sbjct: 697 GCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVV---RQEERCVCRDGRLHCRQIR 753
Query: 823 --------------------------GHVTCQEGAACGPHEEC---------RLEDGVQA 847
++CQ AA H EC ++DG
Sbjct: 754 LIGQSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDGLMDDGRGG 813
Query: 848 C--------------HATG------CGRCLANGGI------------------HYITLDG 869
C +++G C C G HYIT DG
Sbjct: 814 CVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYGSGHYITFDG 873
Query: 870 RVYDLHGSCSYVLAQ-VCHPKPGDEDFSIVLEKNAAGDL-----QRLLVTVAGQVVSLAQ 923
+ YD G CSYV Q C FSI+ E G + + + + + L
Sbjct: 874 KYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKLED 933
Query: 924 GQQVTV---DGEAVALPVAVGRVRVTAE-GRNMVLQTTKGLRLLFDGDAHLLMSIPSPFR 979
+V + +G VA T E G+ +V++++ G+ +++D + + + ++
Sbjct: 934 KHRVVIQRDEGHHVAY--------TTREVGQYLVVESSTGIIVIWDKRTTVFIKLAPSYK 985
Query: 980 GRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEGCGPQGCPVCLAE 1039
G +CGLCGNF+ ++DF + SS FG +W+ + P C
Sbjct: 986 GTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTCPDVSTNPEP-----CSLN 1040
Query: 1040 ETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCA--QKGDKAFLCRSLAAY 1097
+ + C L++ F+ C + + P ++ CV+D C+ GD C ++A+Y
Sbjct: 1041 PHRRSWAEKQCSILKS--SVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASY 1098
Query: 1098 TAACQAAGVAVKPWRTDSFCPLHC----PAHS---HYSICTRTCQGSCAALSGL-TGCTT 1149
C G V WRT CP+ C P H HY C +C ++G+ + +
Sbjct: 1099 AQECTKEGACVF-WRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNISV 1157
Query: 1150 RCFEGC--EC-DDRFLLSQGV--CIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSS 1204
EGC C DR + + + C+ CGC + P +S+ T + + C C++SS
Sbjct: 1158 SYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGASVPTEETCKSCVCTNSS 1217
Query: 1205 GLTCQ 1209
+ C+
Sbjct: 1218 QVVCR 1222
Score = 285 bits (730), Expect = 2e-76
Identities = 268/1033 (25%), Positives = 402/1033 (38%), Gaps = 189/1033 (18%)
Query: 474 CQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRS 533
C WG+ HY T DG F F G C+Y ++ C G + F V + ++A + S
Sbjct: 37 CSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRG---SYKEFAVHLKRGPGQAEAPAGVES 93
Query: 534 VTLQIYNHSLTLSARWPRKLQV-DGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFD 592
+ L I + ++ L+ R L V +G V+ P LL S A V + +GL+L ++
Sbjct: 94 ILLTIKDDTIYLT----RHLAVLNGAVVSTPHYSPGLL-IEKSDAYTKVYSRAGLTLMWN 148
Query: 593 GDSFVRLRVPAAYAASLCGLCGNYNQ-DPADDLKAVGGKPAGWQVGGAQG-------CGE 644
+ + L + + CGLCG+YN + + G + + G Q C +
Sbjct: 149 REDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLEFGNMQKINQPDVVCED 208
Query: 645 CVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGH 704
+ P+ C+ + E C + + A C LVP Y + C D C+ G
Sbjct: 209 PEEEVAPASCSEHRAE-------CERLLTAEA-FADCQDLVPLEPYLRACQQDRCRCPGG 260
Query: 705 PGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEG 764
+C VA + C AG + G WR CP CP + Y G C +C L
Sbjct: 261 DTCVCSTVAEFSRQCSHAGGRPGNWRTATLCPKTCPGNLVYLESGSPCMDTCSHLEVSSL 320
Query: 765 CESACREGCVCDAGFVLS--GDT-CVPVGQCGC-LHDGRYYPLGEVFYPGPECERRCECG 820
CE +GC C G V GD+ CVPV QC C LH G ++ PG E C
Sbjct: 321 CEEHRMDGCFCPEGTVYDDIGDSGCVPVSQCHCRLH-------GHLYTPGQEITNDC--- 370
Query: 821 PGGHVTCQEGAACGPHEECRLEDGVQACHATGC-GRCLANGGIHYITLDGRVYDLHGSCS 879
E+C G C C G C GG H T DG+ Y HG C
Sbjct: 371 ----------------EQCVCNAGRWVCKDLPCPGTCALEGGSHITTFDGKTYTFHGDCY 414
Query: 880 YVLAQVCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVSLAQGQQVTV----DGEAVA 935
YVLA+ H ++ ++++ E G + T VV LA ++ V DG +
Sbjct: 415 YVLAKGDH----NDSYALLGELAPCGSTDK--QTCLKTVVLLADKKKNVVVFKSDGSVLL 468
Query: 936 LPVAVGRVRVTA-------EGRNMVLQTTKGLRLLFD--GDAHLLMSIPSPFRGRLCGLC 986
+ V VTA ++++ G+RL L +++ +G++ GLC
Sbjct: 469 NELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGLC 528
Query: 987 GNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEGCGPQGCPVCLAEETAPYES 1046
GNFNG DDF +G ++ F W+ S C + P L E+A Y +
Sbjct: 529 GNFNGLEGDDFKTASGLVEATGAGFANTWKAQSS---CHDKLDWLDDPCSLNIESANY-A 584
Query: 1047 NEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGV 1106
C L+ + PF C + + P+EY+++C YD C + ++ LC +L++Y AC A GV
Sbjct: 585 EHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGV 644
Query: 1107 AVKPWRTDSFCPL---HCPAHSHYSICTRTCQGSCAALSGLTGCTTRCF---EGCECDDR 1160
+ WR + C CP + TCQ +C +LS F +GC C D
Sbjct: 645 MLWGWR-EHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGCPDH 703
Query: 1161 -FLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSC------------------- 1200
FL +G C+P+ C C H G YL ++ + ERC C
Sbjct: 704 TFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQE--ERCVCRDGRLHCRQIRLIGQSCTA 761
Query: 1201 ---------------SSSSGLTCQ--AAG-----CPPGRVC------------------- 1219
S L+CQ AAG C G VC
Sbjct: 762 PKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDGLMDDGRGGCVVEKECP 821
Query: 1220 ------------EVKAEARNCWATRG--LCVLSVGANLTTFDGARGATTSPG-VYELSSR 1264
++K + C RG +C +V + G+ T G Y+
Sbjct: 822 CVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDFDGH 881
Query: 1265 CPGLQNTIPWYRVVAEVQICHGKTEAVGQVHIFFQD---GMVTLTPNKGVWVNGLRVDLP 1321
C VA C G+ ++G I ++ G +T +K + + R +L
Sbjct: 882 C----------SYVAVQDYC-GQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELK 930
Query: 1322 AEKLASVSVSRTPDGS-----------LLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCG 1370
E V + R L+V G+ V V + ++ + G +CG
Sbjct: 931 LEDKHRVVIQRDEGHHVAYTTREVGQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCG 990
Query: 1371 ACGNFDGDQTNDW 1383
CGNFD ND+
Sbjct: 991 LCGNFDHRSNNDF 1003
Score = 139 bits (350), Expect = 2e-32
Identities = 121/484 (25%), Positives = 191/484 (39%), Gaps = 76/484 (15%)
Query: 385 CVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLV 444
CV GC C G + + C C N + +G++ D C+ C C G V
Sbjct: 796 CVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVD--CNT-CTCKRG--RWV 850
Query: 445 CTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPC 504
CT A C HG C +G HY+T DG +DF G C Y+
Sbjct: 851 CTQAVC-------------HGT-------CSIYGSGHYITFDGKYYDFDGHCSYVAVQDY 890
Query: 505 HGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD-GVFVALP 563
G +F++ N G+ V+ ++++ + + L L + +Q D G VA
Sbjct: 891 CGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYT 950
Query: 564 FQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADD 623
G +VV +++G+ + +D + V +++ +Y ++CGLCGN++ +D
Sbjct: 951 --------TREVGQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNND 1002
Query: 624 LKAVGGKPAGWQVGGAQGCGECVSKP----CPSPCTPEQQESFGGPDACGVISATDGPLA 679
++ E + P P PC+ C ++ ++ +
Sbjct: 1003 FTTRDHMVVSSELDFGNSWKEAPTCPDVSTNPEPCSLNPHRRSWAEKQCSILKSS--VFS 1060
Query: 680 PCHGLVPPAQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPL 737
CH V P +++ C+ D+C G C AVA+Y C GA + WR PD CP+
Sbjct: 1061 ICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACV-FWRTPDLCPI 1119
Query: 738 QC----PAHS---HYELCGDSCPVSCP---------SLSAPEGCESAC-REGCVCDAGFV 780
C P H HYE CG+ +C S+S EGC C ++ + +
Sbjct: 1120 FCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDL- 1178
Query: 781 LSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTC-----------QE 829
CV +CGC + +YP G P E + C C V C Q+
Sbjct: 1179 ---KKCVTADKCGCYVEDTHYPPG-ASVPTEETCKSCVCTNSSQVVCRPEEGKILNQTQD 1234
Query: 830 GAAC 833
GA C
Sbjct: 1235 GAFC 1238
Score = 130 bits (326), Expect = 1e-29
Identities = 114/406 (28%), Positives = 169/406 (41%), Gaps = 38/406 (9%)
Query: 57 TCKEQGGQGVCLPNY-EATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLT 115
TC + G+ VC TC ++G HY +FDG+ +DF G C+YV C S+ G
Sbjct: 841 TCTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLG-- 898
Query: 116 PFTVTTKNENRGNPAVSYVRVVTVAALGTNISIH-KDEIGKVRVNGVLTALPVSVADGRI 174
F++ T+N G V+ + + + T + + K + R G A G+
Sbjct: 899 SFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYTTREV-GQY 957
Query: 175 SVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGT 234
V + ++ G+ V +D V + L SY G VCGLCGN D NND +
Sbjct: 958 LVVESST--------GIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHM 1009
Query: 235 LAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTC 294
+ S +G SW+ P C D P C + + C L F+ C
Sbjct: 1010 VVSSELDFGNSWKEA---PTCPDVSTNPEP-CSLNPHRRSWAEKQCSILKSSV---FSIC 1062
Query: 295 HAHVPPESFFKGCVLDVCM--GGGDHDILCKALASYVAACQAAGVVIEDWRAQVGCEITC 352
H+ V P+ F++ CV D C GGD + C A+ASY C G + WR C I C
Sbjct: 1063 HSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACV-FWRTPDLCPIFC 1121
Query: 353 PENS-------HYEVCGPPCPASCPSPAPL---TTPAVCEGPCVEGCQCDAG-FVLSADR 401
+ HYE CG +C + + + + EG C C D + +
Sbjct: 1122 DYYNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEG-CYPRCPKDRPIYEEDLKK 1180
Query: 402 CVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTP 447
CV + CGC+ T++ G+ + TC C C +VC P
Sbjct: 1181 CVTADK-CGCYVEDTHYPPGASVPTEETCKS-CVC-TNSSQVVCRP 1223
Score = 127 bits (319), Expect = 8e-29
Identities = 122/451 (27%), Positives = 172/451 (38%), Gaps = 56/451 (12%)
Query: 54 PQETCKEQGGQGVCLPNYEATCWLW---------GDPHYHSFDGRKFDFQGTCNYVLATT 104
P TC G Q V + + + CW W GDPHY +FDG + +QG C YVL
Sbjct: 4452 PMPTCSN-GLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEE 4510
Query: 105 GCLGVSTQGLTPFTV-TTKNENRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLT 163
V G+ N+ P VR T L + + ++ +V+VN
Sbjct: 4511 ISPSVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQV-QVQVNRQAV 4569
Query: 164 ALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYH---GAVCGLCGNM 220
ALP G G + + + + G+ VSY+ V LP YH G CG
Sbjct: 4570 ALPYK-KYGLEVYQSGINYVVDIPELGVLVSYN-GLSFSVRLP--YHRFGNNTKGQCGTC 4625
Query: 221 DRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCP---TCPEDRLEQYEGP 277
++D + P+G + + W L D + CP + + G
Sbjct: 4626 TNTTSDDCILPSGEIVSNCEAAADQW-------LVNDPSKPHCPHSSSTTKRPAVTVPGG 4678
Query: 278 GFCGPLAPGTGGP---------FTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASY 328
G P T P F CHA VPP+ ++ CV D C G + C +L +Y
Sbjct: 4679 GKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSCFMPGS-SLECASLQAY 4737
Query: 329 VAACQAAGVVIEDWRAQV--GCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCV 386
A C + + DWR C + CP + Y+ CGP +C S + V V
Sbjct: 4738 AALCAQQNICL-DWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQNNTV----LV 4792
Query: 387 EGCQCDAG---FVLSADRCVPLNNGCGC-WANGTYHEAGSEFWADGTCSQWCRCGPGGGS 442
EGC C G + D CV CGC + E G F D C C C GG
Sbjct: 4793 EGCFCPEGTMNYAPGFDVCV---KTCGCVGPDNVPREFGEHFEFD--CKN-CVCLEGGSG 4846
Query: 443 LVCTPASCGLGEVCGLLPSGQHGCQPVSTAE 473
++C P C V + G + V+ A+
Sbjct: 4847 IICQPKRCSQKPVTHCVEDGTYLATEVNPAD 4877
Score = 127 bits (318), Expect = 1e-28
Identities = 114/425 (26%), Positives = 167/425 (39%), Gaps = 42/425 (9%)
Query: 816 RCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCG-RCLANGGIHYITLDGRVYDL 874
+ EC P TC G + R+ED C C C G HY+T DG Y
Sbjct: 4445 KVECEPPPMPTCSNGL-----QPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSY 4499
Query: 875 HGSCSYVLAQVCHPKPGDEDFSIVLEK-----NAAGDLQRLLV-------TVAGQVVSLA 922
G+C+YVL + P ++F + ++ N R L+ + V +
Sbjct: 4500 QGNCTYVLVE--EISPSVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMP 4557
Query: 923 QGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTK-GLRLLFDGDAHLLMSIPSP---F 978
QV V+ +AVALP + V G N V+ + G+ + ++G L S+ P F
Sbjct: 4558 MQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVLVSYNG---LSFSVRLPYHRF 4614
Query: 979 RGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSK-GCGEGCGPQGCPVCL 1037
G CG SDD +LP+G S+ E W V SK C P
Sbjct: 4615 GNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVT 4674
Query: 1038 AE---ETAPYES---NEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLC 1091
+T P++ + C +++ FA C A++ P Y+ CV+D C G + C
Sbjct: 4675 VPGGGKTTPHKDCTPSPLCQLIKD--SLFAQCHALVPPQHYYDACVFDSCFMPG-SSLEC 4731
Query: 1092 RSLAAYTAACQAAGVAVKPWR--TDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTT 1149
SL AY A C + + WR T C + CP+H Y C + +C + S T
Sbjct: 4732 ASLQAYAALCAQQNICL-DWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQN-NT 4789
Query: 1150 RCFEGCECDDRFL-LSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTC 1208
EGC C + + + G + V+ CGC DC SG+ C
Sbjct: 4790 VLVEGCFCPEGTMNYAPGFDVCVKTCGCVGPDNVPREFGEHFEFDCKNCVCLEGGSGIIC 4849
Query: 1209 QAAGC 1213
Q C
Sbjct: 4850 QPKRC 4854
Score = 122 bits (307), Expect = 2e-27
Identities = 137/480 (28%), Positives = 190/480 (39%), Gaps = 59/480 (12%)
Query: 56 ETCKEQGGQGVC--LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLA------TTGCL 107
E C G+ VC LP TC L G H +FDG+ + F G C YVLA + L
Sbjct: 371 EQCVCNAGRWVCKDLP-CPGTCALEGGSHITTFDGKTYTFHGDCYYVLAKGDHNDSYALL 429
Query: 108 GVSTQGLTPFTVTTKNENRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPV 167
G L P T K VV +A N+ + K + G V +N + LP
Sbjct: 430 GE----LAPCGSTDKQ-------TCLKTVVLLADKKKNVVVFKSD-GSVLLNELQVNLPH 477
Query: 168 SVADGRISVAQGASKALLVA---DFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNP 224
A SV + +S ++V+ LQV ++ VTL + G V GLCGN +
Sbjct: 478 VTAS--FSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGLCGNFNGLE 535
Query: 225 NNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLA 284
+D +G + + + +W+A C D+ C + +C L
Sbjct: 536 GDDFKTASGLVEATGAGFANTWKAQS---SCHDKLDWLDDPCSLNIESANYAEHWCS-LL 591
Query: 285 PGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVVIEDWRA 344
T PF CH+ V P ++K C D C + D LC AL+SY AC A GV++ WR
Sbjct: 592 KKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGVMLWGWRE 651
Query: 345 QVGCEI---TCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQC-DAGFVLSAD 400
V C +CP + + C +C S + + + V+GC C D F+
Sbjct: 652 HV-CNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGCPDHTFLDEKG 710
Query: 401 RCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLP 460
RCVPL C C+ G Y EAG D Q RC G L C +G+ C P
Sbjct: 711 RCVPLAK-CSCYHRGLYLEAG-----DVVVRQEERCVCRDGRLHCRQIRL-IGQSC-TAP 762
Query: 461 SGQHGCQPVS--------TAECQAWGDPHY--------VTLDGHRFDFQGTCEYLLSAPC 504
C ++ CQ +Y V DG D +G C PC
Sbjct: 763 KIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDGLMDDGRGGCVVEKECPC 822
Score = 117 bits (294), Expect = 6e-26
Identities = 119/428 (27%), Positives = 183/428 (42%), Gaps = 56/428 (13%)
Query: 459 LPSGQHGCQPVSTAE-------------CQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCH 505
+P+ +G QPV + C WGDPHYVT DG + +QG C Y+L
Sbjct: 4453 MPTCSNGLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEIS 4512
Query: 506 GPPLGAENFTVTVANEH-RGSQAVSYTRSVTLQIYNHSLTLSA----RWPRKLQVDGVFV 560
+NF V + N H + VS R++ ++ + + ++QV+ V
Sbjct: 4513 P---SVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAV 4569
Query: 561 ALPFQLDSLLHAHLSGADVVVTTTS-GLSLAFDGDSFVRLRVP-AAYAASLCGLCGNYNQ 618
ALP++ L + SG + VV G+ ++++G SF +R+P + + G CG
Sbjct: 4570 ALPYKKYG-LEVYQSGINYVVDIPELGVLVSYNGLSF-SVRLPYHRFGNNTKGQCGTCTN 4627
Query: 619 DPADDLKAVGGK-PAGWQVGGAQGCGECVSKP-CPSPCTPEQQESF---GGPDACGVISA 673
+DD G+ + + Q SKP CP + ++ + GG
Sbjct: 4628 TTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDC 4687
Query: 674 TDGPL---------APCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGA 724
T PL A CH LVPP Y+ C+ D+C + G C ++ Y A C
Sbjct: 4688 TPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSCFMPG-SSLECASLQAYAALCAQQNI 4746
Query: 725 QLGEWRRPDF--CPLQCPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAG---F 779
L +WR C ++CP+H Y+ CG + +C S S+ + + EGC C G +
Sbjct: 4747 CL-DWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQN-NTVLVEGCFCPEGTMNY 4804
Query: 780 VLSGDTCVPVGQCGCL-HDGRYYPLGEVFYPGPECERRCECGPGGH-VTCQ-EGAACGPH 836
D CV CGC+ D GE F +C + C C GG + CQ + + P
Sbjct: 4805 APGFDVCVKT--CGCVGPDNVPREFGEHF--EFDC-KNCVCLEGGSGIICQPKRCSQKPV 4859
Query: 837 EECRLEDG 844
C +EDG
Sbjct: 4860 THC-VEDG 4866
>gi|239755901 PREDICTED: chromosome 12 open reading frame 64 [Homo
sapiens]
Length = 2250
Score = 303 bits (777), Expect = 6e-82
Identities = 304/1177 (25%), Positives = 458/1177 (38%), Gaps = 196/1177 (16%)
Query: 48 HGVTCRPQETCKEQ-----GGQGVCLPNY----EATCWLWGDPHYHSFDGRKFDFQGTCN 98
+G C TC Q G + +PN + C WG H+ +FDG + F G C+
Sbjct: 28 NGAFCSKTGTCDCQIFQALGTRCQIIPNMGNGRDGICKTWGQYHFETFDGIYYYFPGNCS 87
Query: 99 YVLATTGCLGVSTQGLTPFTVTTKNENR--GNPAVSYVRVVTVAALGTNISIHKDEIGKV 156
Y+ A C + + +TV N + G+ Y + + I I+ EI K
Sbjct: 88 YIFAKD-CGDLEPR----YTVWVHNSPKCLGSVYSCYRSISLFFSNQEEIRIYGHEIKK- 141
Query: 157 RVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGL 216
NG+ LP ++ G+I + + A L+ FG +++D + + L + G CGL
Sbjct: 142 --NGISLTLPQTI--GQIFIEKLADYILVKTTFGFSLAWDGISGIYLKLSEDHKGKSCGL 197
Query: 217 CGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEG 276
CGN + ++D + I ++ SW D P + +E
Sbjct: 198 CGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVLTPSDFPNPCSSGMPAFEA 257
Query: 277 PGF-CGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAA 335
F C L PF +CH ++ P + CV D+C D + C+A Y AC A
Sbjct: 258 IFFKCQILLQF---PFLSCHEYIDPYLYIASCVNDLCKTDDD-ETYCRAATEYARACSHA 313
Query: 336 GVVIEDWRAQV-GCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGP---CVEGCQC 391
G I+DWR C C ++ + C CP +C T C G C++GC C
Sbjct: 314 GYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTC------TFEKQCLGSNLHCLDGCYC 367
Query: 392 DAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCG 451
G V+ C+ L N C C +G + GS+ + C++ C C GG CT C
Sbjct: 368 PDGLVMDNGTCISLEN-CPCGFHGLAYSVGSKI--EQECTE-CVCV--GGVWNCTEQDC- 420
Query: 452 LGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGA 511
PV +C GD H+ T DG + F G C+Y+L G
Sbjct: 421 ----------------PV---QCSVVGDSHFTTFDGRHYSFIGMCQYILVKGT-----GK 456
Query: 512 ENFTVTVANEH-RGSQAVSYTRSVTLQI---YNHSLTLSARWPRKLQVDGVFVALP---F 564
+ FT+T+ + + +S+TL + +N +TL G + P F
Sbjct: 457 DKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGR--------GGQILTSPNQGF 508
Query: 565 QLDSLLHAH-LSGADVVVTTTSGLSLAF--DGDSFVRLRVPAAYAASLCGLCGNYNQDPA 621
L+ ++ LS +++ TT GL + F DG+ + +++ +A+ GLCG +N +
Sbjct: 509 NLNGIVEIQTLSSLFILLKTTFGLKILFAIDGER-IYIQLTSAWKRRTLGLCGTFNGNIR 567
Query: 622 DDLKAVGGKPAG--------WQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISA 673
DD + G G W+V C V P PC QQ + G C VI
Sbjct: 568 DDFLSPSGMIEGTPQLHANAWRVSST--CFAPVHVPVVDPCNINQQ-NIGYAAHCDVIHQ 624
Query: 674 TDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPD 733
APCH + P Y+Q C DAC+ LC A+A Y C G + +
Sbjct: 625 E--LFAPCHIYISPGLYYQLCRHDACKCGS--SCLCNALAHYAYLCGQHGVPIDFRTQIS 680
Query: 734 FCPLQCPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAG--FVLSGDTCVPVGQ 791
FC + C Y C C SC SLS+PE C C EGC C G + + + CVP+
Sbjct: 681 FCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEGKFYEDTLNFCVPIFH 740
Query: 792 CGCLHDGRYYPLGEVF--------------------------------------YPGPE- 812
C C + G Y GE+ +P PE
Sbjct: 741 CRCHYRGSVYQPGELIPTPSGLCQCSNGTVKCDELATPSAVHICPEGKEYFDCRFPDPEL 800
Query: 813 ------CERRC-------ECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGC-GRCLA 858
CE C C P C G C P CR G+ C C C
Sbjct: 801 PAGGVNCETTCANLAMNFTCTPSS--PCISGCVCAP-GVCR--RGMFNCTYYPCPAVCTI 855
Query: 859 NGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQV 918
G HY + DG YD C L + D D S++ + D +V +
Sbjct: 856 YGDRHYYSFDGLEYDYISDCQVFLIK----SADDSDISVIAQNKKCFDND--IVCSKSVL 909
Query: 919 VSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRN-----------MVLQTTKGLRLLFDGD 967
+S+ + D P + E ++ +V K + +L+D
Sbjct: 910 ISVGDTEIYLND-----TPYKQKQSGFFLENKSTYQLWKAGYYIVVYFPEKDITILWDRK 964
Query: 968 AHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEG 1027
+ + + ++ +L GLCGNF+ S+D N + FG +W + G + E
Sbjct: 965 TTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSWAL-GQCESPDET 1023
Query: 1028 CGPQGCPVCLAEETA-PYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQK-- 1084
P C A + PY E C L + FA+C+ V+ + + + C D C
Sbjct: 1024 IKP-----CEAHQNKFPYAKKE-CSILYS--DIFASCRNVIDVTSFAKNCHEDTCNCNLG 1075
Query: 1085 GDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHC 1121
GD LC S+AAY C G+++ WR+ + C L C
Sbjct: 1076 GDCECLCTSIAAYAYKCCQEGISIH-WRSSTVCSLDC 1111
Score = 255 bits (652), Expect = 2e-67
Identities = 227/841 (26%), Positives = 343/841 (40%), Gaps = 99/841 (11%)
Query: 424 FWADGTCSQWCRCGPGGGSLVCTPASC------GLGEVCGLLPSGQHGCQPVSTAECQAW 477
F G+C C G+ +C LG C ++P+ +G + C+ W
Sbjct: 16 FSPSGSCPYECL----NGAFCSKTGTCDCQIFQALGTRCQIIPNMGNGRDGI----CKTW 67
Query: 478 GDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAV-SYTRSVTL 536
G H+ T DG + F G C Y+ + C +TV V N + +V S RS++L
Sbjct: 68 GQYHFETFDGIYYYFPGNCSYIFAKDCGDLE---PRYTVWVHNSPKCLGSVYSCYRSISL 124
Query: 537 QIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSF 596
N + +++ +G+ + LP + + L+ ++V TT G SLA+DG S
Sbjct: 125 FFSNQEEIRI--YGHEIKKNGISLTLPQTIGQIFIEKLADY-ILVKTTFGFSLAWDGISG 181
Query: 597 VRLRVPAAYAASLCGLCGNYNQDPADDL--------KAVGGKPAGWQVGGAQGCGECVSK 648
+ L++ + CGLCGNYN +DD + + W V +CV
Sbjct: 182 IYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDT-KCVLT 240
Query: 649 PC--PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPG 706
P P+PC+ C ++ P CH + P Y C+ D C+
Sbjct: 241 PSDFPNPCSSGMPAFEAIFFKCQIL--LQFPFLSCHEYIDPYLYIASCVNDLCKTDDDET 298
Query: 707 GLCPAVATYVAACQAAGAQLGEWRRPDF--CPLQCPAHSHYELCGDSCPVSCPSLSAPEG 764
C A Y AC AG + +WR DF C +C + C CP +C G
Sbjct: 299 -YCRAATEYARACSHAGYPIQDWR-DDFPACTDKCDDSFVHRDCISCCPPTCTFEKQCLG 356
Query: 765 CESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGH 824
C +GC C G V+ TC+ + C C G Y +G + E+ C
Sbjct: 357 SNLHCLDGCYCPDGLVMDNGTCISLENCPCGFHGLAYSVGS------KIEQECT------ 404
Query: 825 VTCQEGAACGPHEECRLEDGVQACHATGCG-RCLANGGIHYITLDGRVYDLHGSCSYVLA 883
EC GV C C +C G H+ T DGR Y G C Y+L
Sbjct: 405 -------------ECVCVGGVWNCTEQDCPVQCSVVGDSHFTTFDGRHYSFIGMCQYILV 451
Query: 884 QVCHPKPGDEDFSIVLEKNAAGD------LQRLLVTVA---GQVVSLAQGQQV-TVDGEA 933
+ G + F+I L+K LQ + + + + V+L +G Q+ T +
Sbjct: 452 K----GTGKDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGRGGQILTSPNQG 507
Query: 934 VALPVAVGRVRV-TAEGRNMVLQTTKGLRLLF--DGDAHLLMSIPSPFRGRLCGLCGNFN 990
L G V + T ++L+TT GL++LF DG+ + + + S ++ R GLCG FN
Sbjct: 508 FNLN---GIVEIQTLSSLFILLKTTFGLKILFAIDGE-RIYIQLTSAWKRRTLGLCGTFN 563
Query: 991 GNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEGCGPQGCPVCLAEETAPYESNEAC 1050
GN DDF+ P+G + + AWRV SS P P + ++ Y ++ C
Sbjct: 564 GNIRDDFLSPSGMIEGTPQLHANAWRV--SSTCFAPVHVPVVDPCNINQQNIGYAAH--C 619
Query: 1051 GQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKP 1110
+ Q FA C +SP Y++ C +D C K + LC +LA Y C GV +
Sbjct: 620 DVIH--QELFAPCHIYISPGLYYQLCRHDAC--KCGSSCLCNALAHYAYLCGQHGVPIDF 675
Query: 1111 WRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQ--GVC 1168
SFC + C Y C+ C SC +LS C+ C EGC C + C
Sbjct: 676 RTQISFCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEGKFYEDTLNFC 735
Query: 1169 IPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPG-RVCEVKAEARN 1227
+P+ C C + G + T S C CS+ + + C P +C E +
Sbjct: 736 VPIFHCRCHYRGSVYQPGELIPTP--SGLCQCSNGT-VKCDELATPSAVHICPEGKEYFD 792
Query: 1228 C 1228
C
Sbjct: 793 C 793
Score = 80.1 bits (196), Expect = 1e-14
Identities = 100/440 (22%), Positives = 166/440 (37%), Gaps = 73/440 (16%)
Query: 818 ECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGS 877
+CG G C P EC RC + IT DG L+
Sbjct: 1416 DCGFRGRPVQVNSDICCPEWECPC-------------RCSMLSELSIITFDGNNAALYSM 1462
Query: 878 CSYVLAQVCHPKPGDEDFSIV----LEKNAAGDLQRL------LVTVAGQVVSLAQGQQV 927
SY+L ++ PG+ + + + + +G + L + T +++ ++V
Sbjct: 1463 ASYILVRI----PGEIIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLARKV 1518
Query: 928 TVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHL--LMSIPSPFRGRLC-- 983
VD V LP + + + G V+ T GL + + +HL ++ I FR L
Sbjct: 1519 EVDSIVVPLPFSSQELSIEDSGSMYVITTPAGLIIKW---SHLTGIIDIHFGFRFNLSSY 1575
Query: 984 --GLCGNFNGNWSDDFVLPNGSAASSVETFGA---AWRVPGS----SKGCGEGCGPQGCP 1034
GLCG N + DD + NG+ +++E G +W + S + C C
Sbjct: 1576 TEGLCGICNEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTMRRPVRNCTEHDCS 1635
Query: 1035 VCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSL 1094
C+ L N + F C +SP ++ + + + C +L
Sbjct: 1636 QCI--------------DLLNRR-IFIPCHDKVSPEDFCEKMWINYTYFWN---YECDAL 1677
Query: 1095 AAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTT--RCF 1152
+AY A C + ++ WRT +C L CP Y C R C+ G T+
Sbjct: 1678 SAYVALCNKFDICIQ-WRTPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSCLNLR 1736
Query: 1153 EGCECDDRFLLSQ---GVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCS---CSSSSGL 1206
E C C +L + CIP ++C CT + P + + + + C+ C + +
Sbjct: 1737 EDCVCKVGTVLHRPHSAQCIPEKECACT-DSEDQPRTAGEIWNGGIDECTLYKCLENGSI 1795
Query: 1207 TCQAAGC--PPGRVCEVKAE 1224
C P VCE +AE
Sbjct: 1796 IPIEPDCDEEPTPVCEREAE 1815
Score = 78.2 bits (191), Expect = 5e-14
Identities = 88/345 (25%), Positives = 130/345 (37%), Gaps = 46/345 (13%)
Query: 474 CQAWGDPHYVTLDGHRFDFQGTCEYLL-SAPCHGPPLGAENFTVTVANEHRGSQAVSYTR 532
C + +T DG+ Y+L P E ++ A R S
Sbjct: 1441 CSMLSELSIITFDGNNAALYSMASYILVRIPGEIIVAHIEKCSMNQAPSGRISGLCFKKL 1500
Query: 533 SVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFD 592
+VT I H + ++ R RK++VD + V LPF L SG+ V+TT +GL + +
Sbjct: 1501 NVTTPI--HKIIVN-RLARKVEVDSIVVPLPFSSQEL-SIEDSGSMYVITTPAGLIIKWS 1556
Query: 593 G-----DSFVRLRVP-AAYAASLCGLCGNYNQDPADDLKAVGGKPA-----------GWQ 635
D R ++Y LCG+C N+DP DDL+ G W+
Sbjct: 1557 HLTGIIDIHFGFRFNLSSYTEGLCGIC---NEDPDDDLRMQNGTIITNMEDIGLFIESWE 1613
Query: 636 VGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPL-APCHGLVPPAQYFQGC 694
+ + E + CT D I + + PCH V P + +
Sbjct: 1614 I---EKSFEVTMRRPVRNCTEH--------DCSQCIDLLNRRIFIPCHDKVSPEDFCEKM 1662
Query: 695 LLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPV 754
++ + C A++ YVA C + +WR PD+C L CP Y+ C C
Sbjct: 1663 WINYTYFWNYE---CDALSAYVALCNKFDICI-QWRTPDYCSLSCPEGKEYQPCVRPCEA 1718
Query: 755 SCPSLSAPEGCESA--CREGCVCDAGFVL---SGDTCVPVGQCGC 794
G S RE CVC G VL C+P +C C
Sbjct: 1719 RTCLNQWFYGHTSCLNLREDCVCKVGTVLHRPHSAQCIPEKECAC 1763
Score = 65.1 bits (157), Expect = 5e-10
Identities = 89/389 (22%), Positives = 139/389 (35%), Gaps = 54/389 (13%)
Query: 61 QGGQGVCLPNYEATCW--LWGDPHYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLTPFT 118
Q +C P +E C + + +FDG +Y+L V G
Sbjct: 1425 QVNSDICCPEWECPCRCSMLSELSIITFDGNNAALYSMASYIL-------VRIPGEIIVA 1477
Query: 119 VTTKNENRGNPAVSYVRVVTVAALGTNISIHKDEIG----KVRVNGVLTALPVSVADGRI 174
K P+ + + L IHK + KV V+ ++ LP S + +
Sbjct: 1478 HIEKCSMNQAPS-GRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQE--L 1534
Query: 175 SVAQGASKALLVADFGLQVSYD---------WNWRVDVTLPSSYHGAVCGLCGNMDRNPN 225
S+ S ++ GL + + + +R ++ SSY +CG+C + +P+
Sbjct: 1535 SIEDSGSMYVITTPAGLIIKWSHLTGIIDIHFGFRFNL---SSYTEGLCGIC---NEDPD 1588
Query: 226 NDQVFPNGTLAPS---IPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGP 282
+D NGT+ + I ++ SW + R C E Q C
Sbjct: 1589 DDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTM---RRPVRNCTEHDCSQ------CID 1639
Query: 283 LAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVVIEDW 342
L F CH V PE F + ++ C AL++YVA C + I+ W
Sbjct: 1640 LL--NRRIFIPCHDKVSPEDFCEKMWINYTYFWNYE---CDALSAYVALCNKFDICIQ-W 1693
Query: 343 RAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVL---SA 399
R C ++CPE Y+ C PC A C E C C G VL +
Sbjct: 1694 RTPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSCLN-LREDCVCKVGTVLHRPHS 1752
Query: 400 DRCVPLNNGCGCWANGTYHEAGSEFWADG 428
+C+P C C + E W G
Sbjct: 1753 AQCIP-EKECACTDSEDQPRTAGEIWNGG 1780
Score = 47.0 bits (110), Expect = 1e-04
Identities = 50/204 (24%), Positives = 83/204 (40%), Gaps = 22/204 (10%)
Query: 1193 DCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGA 1252
+C CS + CQ G C++ N G+C + TFDG
Sbjct: 25 ECLNGAFCSKTGTCDCQIFQAL-GTRCQIIPNMGN--GRDGICKTWGQYHFETFDGIYYY 81
Query: 1253 TTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVGQVH-------IFFQDGMVTL 1305
Y + C L+ P Y V H + +G V+ +FF +
Sbjct: 82 FPGNCSYIFAKDCGDLE---PRYTVWV-----HNSPKCLGSVYSCYRSISLFFSNQEEIR 133
Query: 1306 TPNKGVWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQV-WLGANGKVAVIVSNDH 1364
+ NG+ + LP + + + + + D +LV+ G + W G +G + + +S DH
Sbjct: 134 IYGHEIKKNGISLTLP-QTIGQIFIEKLAD-YILVKTTFGFSLAWDGISG-IYLKLSEDH 190
Query: 1365 AGKLCGACGNFDGDQTNDWHDSQE 1388
GK CG CGN++ Q++D+ QE
Sbjct: 191 KGKSCGLCGNYNDIQSDDFIILQE 214
>gi|239750386 PREDICTED: chromosome 12 open reading frame 64 [Homo
sapiens]
Length = 2250
Score = 303 bits (777), Expect = 6e-82
Identities = 304/1177 (25%), Positives = 458/1177 (38%), Gaps = 196/1177 (16%)
Query: 48 HGVTCRPQETCKEQ-----GGQGVCLPNY----EATCWLWGDPHYHSFDGRKFDFQGTCN 98
+G C TC Q G + +PN + C WG H+ +FDG + F G C+
Sbjct: 28 NGAFCSKTGTCDCQIFQALGTRCQIIPNMGNGRDGICKTWGQYHFETFDGIYYYFPGNCS 87
Query: 99 YVLATTGCLGVSTQGLTPFTVTTKNENR--GNPAVSYVRVVTVAALGTNISIHKDEIGKV 156
Y+ A C + + +TV N + G+ Y + + I I+ EI K
Sbjct: 88 YIFAKD-CGDLEPR----YTVWVHNSPKCLGSVYSCYRSISLFFSNQEEIRIYGHEIKK- 141
Query: 157 RVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGL 216
NG+ LP ++ G+I + + A L+ FG +++D + + L + G CGL
Sbjct: 142 --NGISLTLPQTI--GQIFIEKLADYILVKTTFGFSLAWDGISGIYLKLSEDHKGKSCGL 197
Query: 217 CGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEG 276
CGN + ++D + I ++ SW D P + +E
Sbjct: 198 CGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVLTPSDFPNPCSSGMPAFEA 257
Query: 277 PGF-CGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAA 335
F C L PF +CH ++ P + CV D+C D + C+A Y AC A
Sbjct: 258 IFFKCQILLQF---PFLSCHEYIDPYLYIASCVNDLCKTDDD-ETYCRAATEYARACSHA 313
Query: 336 GVVIEDWRAQV-GCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGP---CVEGCQC 391
G I+DWR C C ++ + C CP +C T C G C++GC C
Sbjct: 314 GYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTC------TFEKQCLGSNLHCLDGCYC 367
Query: 392 DAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCG 451
G V+ C+ L N C C +G + GS+ + C++ C C GG CT C
Sbjct: 368 PDGLVMDNGTCISLEN-CPCGFHGLAYSVGSKI--EQECTE-CVCV--GGVWNCTEQDC- 420
Query: 452 LGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGA 511
PV +C GD H+ T DG + F G C+Y+L G
Sbjct: 421 ----------------PV---QCSVVGDSHFTTFDGRHYSFIGMCQYILVKGT-----GK 456
Query: 512 ENFTVTVANEH-RGSQAVSYTRSVTLQI---YNHSLTLSARWPRKLQVDGVFVALP---F 564
+ FT+T+ + + +S+TL + +N +TL G + P F
Sbjct: 457 DKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGR--------GGQILTSPNQGF 508
Query: 565 QLDSLLHAH-LSGADVVVTTTSGLSLAF--DGDSFVRLRVPAAYAASLCGLCGNYNQDPA 621
L+ ++ LS +++ TT GL + F DG+ + +++ +A+ GLCG +N +
Sbjct: 509 NLNGIVEIQTLSSLFILLKTTFGLKILFAIDGER-IYIQLTSAWKRRTLGLCGTFNGNIR 567
Query: 622 DDLKAVGGKPAG--------WQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISA 673
DD + G G W+V C V P PC QQ + G C VI
Sbjct: 568 DDFLSPSGMIEGTPQLHANAWRVSST--CFAPVHVPVVDPCNINQQ-NIGYAAHCDVIHQ 624
Query: 674 TDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPD 733
APCH + P Y+Q C DAC+ LC A+A Y C G + +
Sbjct: 625 E--LFAPCHIYISPGLYYQLCRHDACKCGS--SCLCNALAHYAYLCGQHGVPIDFRTQIS 680
Query: 734 FCPLQCPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAG--FVLSGDTCVPVGQ 791
FC + C Y C C SC SLS+PE C C EGC C G + + + CVP+
Sbjct: 681 FCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEGKFYEDTLNFCVPIFH 740
Query: 792 CGCLHDGRYYPLGEVF--------------------------------------YPGPE- 812
C C + G Y GE+ +P PE
Sbjct: 741 CRCHYRGSVYQPGELIPTPSGLCQCSNGTVKCDELATPSAVHICPEGKEYFDCRFPDPEL 800
Query: 813 ------CERRC-------ECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGC-GRCLA 858
CE C C P C G C P CR G+ C C C
Sbjct: 801 PAGGVNCETTCANLAMNFTCTPSS--PCISGCVCAP-GVCR--RGMFNCTYYPCPAVCTI 855
Query: 859 NGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQV 918
G HY + DG YD C L + D D S++ + D +V +
Sbjct: 856 YGDRHYYSFDGLEYDYISDCQVFLIK----SADDSDISVIAQNKKCFDND--IVCSKSVL 909
Query: 919 VSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRN-----------MVLQTTKGLRLLFDGD 967
+S+ + D P + E ++ +V K + +L+D
Sbjct: 910 ISVGDTEIYLND-----TPYKQKQSGFFLENKSTYQLWKAGYYIVVYFPEKDITILWDRK 964
Query: 968 AHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEG 1027
+ + + ++ +L GLCGNF+ S+D N + FG +W + G + E
Sbjct: 965 TTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSWAL-GQCESPDET 1023
Query: 1028 CGPQGCPVCLAEETA-PYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQK-- 1084
P C A + PY E C L + FA+C+ V+ + + + C D C
Sbjct: 1024 IKP-----CEAHQNKFPYAKKE-CSILYS--DIFASCRNVIDVTSFAKNCHEDTCNCNLG 1075
Query: 1085 GDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHC 1121
GD LC S+AAY C G+++ WR+ + C L C
Sbjct: 1076 GDCECLCTSIAAYAYKCCQEGISIH-WRSSTVCSLDC 1111
Score = 255 bits (652), Expect = 2e-67
Identities = 227/841 (26%), Positives = 343/841 (40%), Gaps = 99/841 (11%)
Query: 424 FWADGTCSQWCRCGPGGGSLVCTPASC------GLGEVCGLLPSGQHGCQPVSTAECQAW 477
F G+C C G+ +C LG C ++P+ +G + C+ W
Sbjct: 16 FSPSGSCPYECL----NGAFCSKTGTCDCQIFQALGTRCQIIPNMGNGRDGI----CKTW 67
Query: 478 GDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAV-SYTRSVTL 536
G H+ T DG + F G C Y+ + C +TV V N + +V S RS++L
Sbjct: 68 GQYHFETFDGIYYYFPGNCSYIFAKDCGDLE---PRYTVWVHNSPKCLGSVYSCYRSISL 124
Query: 537 QIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSF 596
N + +++ +G+ + LP + + L+ ++V TT G SLA+DG S
Sbjct: 125 FFSNQEEIRI--YGHEIKKNGISLTLPQTIGQIFIEKLADY-ILVKTTFGFSLAWDGISG 181
Query: 597 VRLRVPAAYAASLCGLCGNYNQDPADDL--------KAVGGKPAGWQVGGAQGCGECVSK 648
+ L++ + CGLCGNYN +DD + + W V +CV
Sbjct: 182 IYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDT-KCVLT 240
Query: 649 PC--PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPG 706
P P+PC+ C ++ P CH + P Y C+ D C+
Sbjct: 241 PSDFPNPCSSGMPAFEAIFFKCQIL--LQFPFLSCHEYIDPYLYIASCVNDLCKTDDDET 298
Query: 707 GLCPAVATYVAACQAAGAQLGEWRRPDF--CPLQCPAHSHYELCGDSCPVSCPSLSAPEG 764
C A Y AC AG + +WR DF C +C + C CP +C G
Sbjct: 299 -YCRAATEYARACSHAGYPIQDWR-DDFPACTDKCDDSFVHRDCISCCPPTCTFEKQCLG 356
Query: 765 CESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGH 824
C +GC C G V+ TC+ + C C G Y +G + E+ C
Sbjct: 357 SNLHCLDGCYCPDGLVMDNGTCISLENCPCGFHGLAYSVGS------KIEQECT------ 404
Query: 825 VTCQEGAACGPHEECRLEDGVQACHATGCG-RCLANGGIHYITLDGRVYDLHGSCSYVLA 883
EC GV C C +C G H+ T DGR Y G C Y+L
Sbjct: 405 -------------ECVCVGGVWNCTEQDCPVQCSVVGDSHFTTFDGRHYSFIGMCQYILV 451
Query: 884 QVCHPKPGDEDFSIVLEKNAAGD------LQRLLVTVA---GQVVSLAQGQQV-TVDGEA 933
+ G + F+I L+K LQ + + + + V+L +G Q+ T +
Sbjct: 452 K----GTGKDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGRGGQILTSPNQG 507
Query: 934 VALPVAVGRVRV-TAEGRNMVLQTTKGLRLLF--DGDAHLLMSIPSPFRGRLCGLCGNFN 990
L G V + T ++L+TT GL++LF DG+ + + + S ++ R GLCG FN
Sbjct: 508 FNLN---GIVEIQTLSSLFILLKTTFGLKILFAIDGE-RIYIQLTSAWKRRTLGLCGTFN 563
Query: 991 GNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEGCGPQGCPVCLAEETAPYESNEAC 1050
GN DDF+ P+G + + AWRV SS P P + ++ Y ++ C
Sbjct: 564 GNIRDDFLSPSGMIEGTPQLHANAWRV--SSTCFAPVHVPVVDPCNINQQNIGYAAH--C 619
Query: 1051 GQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKP 1110
+ Q FA C +SP Y++ C +D C K + LC +LA Y C GV +
Sbjct: 620 DVIH--QELFAPCHIYISPGLYYQLCRHDAC--KCGSSCLCNALAHYAYLCGQHGVPIDF 675
Query: 1111 WRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQ--GVC 1168
SFC + C Y C+ C SC +LS C+ C EGC C + C
Sbjct: 676 RTQISFCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEGKFYEDTLNFC 735
Query: 1169 IPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPG-RVCEVKAEARN 1227
+P+ C C + G + T S C CS+ + + C P +C E +
Sbjct: 736 VPIFHCRCHYRGSVYQPGELIPTP--SGLCQCSNGT-VKCDELATPSAVHICPEGKEYFD 792
Query: 1228 C 1228
C
Sbjct: 793 C 793
Score = 80.5 bits (197), Expect = 1e-14
Identities = 100/440 (22%), Positives = 166/440 (37%), Gaps = 73/440 (16%)
Query: 818 ECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGS 877
+CG G C P EC RC + IT DG L+
Sbjct: 1416 DCGFRGRPVQVNSDICCPEWECPC-------------RCSMLSELSIITFDGNNAALYSM 1462
Query: 878 CSYVLAQVCHPKPGDEDFSIV----LEKNAAGDLQRL------LVTVAGQVVSLAQGQQV 927
SY+L ++ PG+ + + + + +G + L + T +++ ++V
Sbjct: 1463 ASYILVRI----PGEIIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLARKV 1518
Query: 928 TVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHL--LMSIPSPFRGRLC-- 983
VD V LP + + + G V+ T GL + + +HL ++ I FR L
Sbjct: 1519 EVDSIVVPLPFSSQELSIEDSGSMYVITTPAGLIIKW---SHLTGIIDIHFGFRFNLSSY 1575
Query: 984 --GLCGNFNGNWSDDFVLPNGSAASSVETFGA---AWRVPGS----SKGCGEGCGPQGCP 1034
GLCG N + DD + NG+ +++E G +W + S + C C
Sbjct: 1576 TEGLCGICNEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTMRRPVRNCTEHDCS 1635
Query: 1035 VCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSL 1094
C+ L N + F C +SP ++ + + + C +L
Sbjct: 1636 QCI--------------DLLNRR-IFIPCHDKVSPEDFCEKMWINYTYFWN---YECDAL 1677
Query: 1095 AAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTT--RCF 1152
+AY A C + ++ WRT +C L CP Y C R C+ G T+
Sbjct: 1678 SAYVALCNKFDICIQ-WRTPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSCLNLR 1736
Query: 1153 EGCECDDRFLLSQ---GVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCS---CSSSSGL 1206
E C C +L + CIP ++C CT + P + + + + C+ C + +
Sbjct: 1737 EDCVCKVGTILHRPHSAQCIPEKECACT-DSEDQPRTAGEIWNGGIDECTLYKCLENGSI 1795
Query: 1207 TCQAAGC--PPGRVCEVKAE 1224
C P VCE +AE
Sbjct: 1796 IPIEPDCDEEPTPVCEREAE 1815
Score = 77.8 bits (190), Expect = 7e-14
Identities = 87/345 (25%), Positives = 130/345 (37%), Gaps = 46/345 (13%)
Query: 474 CQAWGDPHYVTLDGHRFDFQGTCEYLL-SAPCHGPPLGAENFTVTVANEHRGSQAVSYTR 532
C + +T DG+ Y+L P E ++ A R S
Sbjct: 1441 CSMLSELSIITFDGNNAALYSMASYILVRIPGEIIVAHIEKCSMNQAPSGRISGLCFKKL 1500
Query: 533 SVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFD 592
+VT I H + ++ R RK++VD + V LPF L SG+ V+TT +GL + +
Sbjct: 1501 NVTTPI--HKIIVN-RLARKVEVDSIVVPLPFSSQEL-SIEDSGSMYVITTPAGLIIKWS 1556
Query: 593 G-----DSFVRLRVP-AAYAASLCGLCGNYNQDPADDLKAVGGKPA-----------GWQ 635
D R ++Y LCG+C N+DP DDL+ G W+
Sbjct: 1557 HLTGIIDIHFGFRFNLSSYTEGLCGIC---NEDPDDDLRMQNGTIITNMEDIGLFIESWE 1613
Query: 636 VGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPL-APCHGLVPPAQYFQGC 694
+ + E + CT D I + + PCH V P + +
Sbjct: 1614 I---EKSFEVTMRRPVRNCTEH--------DCSQCIDLLNRRIFIPCHDKVSPEDFCEKM 1662
Query: 695 LLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPV 754
++ + C A++ YVA C + +WR PD+C L CP Y+ C C
Sbjct: 1663 WINYTYFWNYE---CDALSAYVALCNKFDICI-QWRTPDYCSLSCPEGKEYQPCVRPCEA 1718
Query: 755 SCPSLSAPEGCESA--CREGCVCDAGFVL---SGDTCVPVGQCGC 794
G S RE CVC G +L C+P +C C
Sbjct: 1719 RTCLNQWFYGHTSCLNLREDCVCKVGTILHRPHSAQCIPEKECAC 1763
Score = 64.7 bits (156), Expect = 6e-10
Identities = 88/389 (22%), Positives = 139/389 (35%), Gaps = 54/389 (13%)
Query: 61 QGGQGVCLPNYEATCW--LWGDPHYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLTPFT 118
Q +C P +E C + + +FDG +Y+L V G
Sbjct: 1425 QVNSDICCPEWECPCRCSMLSELSIITFDGNNAALYSMASYIL-------VRIPGEIIVA 1477
Query: 119 VTTKNENRGNPAVSYVRVVTVAALGTNISIHKDEIG----KVRVNGVLTALPVSVADGRI 174
K P+ + + L IHK + KV V+ ++ LP S + +
Sbjct: 1478 HIEKCSMNQAPS-GRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQE--L 1534
Query: 175 SVAQGASKALLVADFGLQVSYD---------WNWRVDVTLPSSYHGAVCGLCGNMDRNPN 225
S+ S ++ GL + + + +R ++ SSY +CG+C + +P+
Sbjct: 1535 SIEDSGSMYVITTPAGLIIKWSHLTGIIDIHFGFRFNL---SSYTEGLCGIC---NEDPD 1588
Query: 226 NDQVFPNGTLAPS---IPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGP 282
+D NGT+ + I ++ SW + R C E Q C
Sbjct: 1589 DDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTM---RRPVRNCTEHDCSQ------CID 1639
Query: 283 LAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVVIEDW 342
L F CH V PE F + ++ C AL++YVA C + I+ W
Sbjct: 1640 LL--NRRIFIPCHDKVSPEDFCEKMWINYTYFWNYE---CDALSAYVALCNKFDICIQ-W 1693
Query: 343 RAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVL---SA 399
R C ++CPE Y+ C PC A C E C C G +L +
Sbjct: 1694 RTPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSCLN-LREDCVCKVGTILHRPHS 1752
Query: 400 DRCVPLNNGCGCWANGTYHEAGSEFWADG 428
+C+P C C + E W G
Sbjct: 1753 AQCIP-EKECACTDSEDQPRTAGEIWNGG 1780
Score = 47.0 bits (110), Expect = 1e-04
Identities = 50/204 (24%), Positives = 83/204 (40%), Gaps = 22/204 (10%)
Query: 1193 DCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGA 1252
+C CS + CQ G C++ N G+C + TFDG
Sbjct: 25 ECLNGAFCSKTGTCDCQIFQAL-GTRCQIIPNMGN--GRDGICKTWGQYHFETFDGIYYY 81
Query: 1253 TTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVGQVH-------IFFQDGMVTL 1305
Y + C L+ P Y V H + +G V+ +FF +
Sbjct: 82 FPGNCSYIFAKDCGDLE---PRYTVWV-----HNSPKCLGSVYSCYRSISLFFSNQEEIR 133
Query: 1306 TPNKGVWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQV-WLGANGKVAVIVSNDH 1364
+ NG+ + LP + + + + + D +LV+ G + W G +G + + +S DH
Sbjct: 134 IYGHEIKKNGISLTLP-QTIGQIFIEKLAD-YILVKTTFGFSLAWDGISG-IYLKLSEDH 190
Query: 1365 AGKLCGACGNFDGDQTNDWHDSQE 1388
GK CG CGN++ Q++D+ QE
Sbjct: 191 KGKSCGLCGNYNDIQSDDFIILQE 214
>gi|239744688 PREDICTED: hypothetical protein LOC283310 [Homo sapiens]
Length = 2250
Score = 303 bits (777), Expect = 6e-82
Identities = 304/1177 (25%), Positives = 458/1177 (38%), Gaps = 196/1177 (16%)
Query: 48 HGVTCRPQETCKEQ-----GGQGVCLPNY----EATCWLWGDPHYHSFDGRKFDFQGTCN 98
+G C TC Q G + +PN + C WG H+ +FDG + F G C+
Sbjct: 28 NGAFCSKTGTCDCQIFQALGTRCQIIPNMGNGRDGICKTWGQYHFETFDGIYYYFPGNCS 87
Query: 99 YVLATTGCLGVSTQGLTPFTVTTKNENR--GNPAVSYVRVVTVAALGTNISIHKDEIGKV 156
Y+ A C + + +TV N + G+ Y + + I I+ EI K
Sbjct: 88 YIFAKD-CGDLEPR----YTVWVHNSPKCLGSVYSCYRSISLFFSNQEEIRIYGHEIKK- 141
Query: 157 RVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGL 216
NG+ LP ++ G+I + + A L+ FG +++D + + L + G CGL
Sbjct: 142 --NGISLTLPQTI--GQIFIEKLADYILVKTTFGFSLAWDGISGIYLKLSEDHKGKSCGL 197
Query: 217 CGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEG 276
CGN + ++D + I ++ SW D P + +E
Sbjct: 198 CGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVLTPSDFPNPCSSGMPAFEA 257
Query: 277 PGF-CGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAA 335
F C L PF +CH ++ P + CV D+C D + C+A Y AC A
Sbjct: 258 IFFKCQILLQF---PFLSCHEYIDPYLYIASCVNDLCKTDDD-ETYCRAATEYARACSHA 313
Query: 336 GVVIEDWRAQV-GCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGP---CVEGCQC 391
G I+DWR C C ++ + C CP +C T C G C++GC C
Sbjct: 314 GYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTC------TFEKQCLGSNLHCLDGCYC 367
Query: 392 DAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCG 451
G V+ C+ L N C C +G + GS+ + C++ C C GG CT C
Sbjct: 368 PDGLVMDNGTCISLEN-CPCGFHGLAYSVGSKI--EQECTE-CVCV--GGVWNCTEQDC- 420
Query: 452 LGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGA 511
PV +C GD H+ T DG + F G C+Y+L G
Sbjct: 421 ----------------PV---QCSVVGDSHFTTFDGRHYSFIGMCQYILVKGT-----GK 456
Query: 512 ENFTVTVANEH-RGSQAVSYTRSVTLQI---YNHSLTLSARWPRKLQVDGVFVALP---F 564
+ FT+T+ + + +S+TL + +N +TL G + P F
Sbjct: 457 DKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGR--------GGQILTSPNQGF 508
Query: 565 QLDSLLHAH-LSGADVVVTTTSGLSLAF--DGDSFVRLRVPAAYAASLCGLCGNYNQDPA 621
L+ ++ LS +++ TT GL + F DG+ + +++ +A+ GLCG +N +
Sbjct: 509 NLNGIVEIQTLSSLFILLKTTFGLKILFAIDGER-IYIQLTSAWKRRTLGLCGTFNGNIR 567
Query: 622 DDLKAVGGKPAG--------WQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISA 673
DD + G G W+V C V P PC QQ + G C VI
Sbjct: 568 DDFLSPSGMIEGTPQLHANAWRVSST--CFAPVHVPVVDPCNINQQ-NIGYAAHCDVIHQ 624
Query: 674 TDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPD 733
APCH + P Y+Q C DAC+ LC A+A Y C G + +
Sbjct: 625 E--LFAPCHIYISPGLYYQLCRHDACKCGS--SCLCNALAHYAYLCGQHGVPIDFRTQIS 680
Query: 734 FCPLQCPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAG--FVLSGDTCVPVGQ 791
FC + C Y C C SC SLS+PE C C EGC C G + + + CVP+
Sbjct: 681 FCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEGKFYEDTLNFCVPIFH 740
Query: 792 CGCLHDGRYYPLGEVF--------------------------------------YPGPE- 812
C C + G Y GE+ +P PE
Sbjct: 741 CRCHYRGSVYQPGELIPTPSGLCQCSNGTVKCDELATPSAVHICPEGKEYFDCRFPDPEL 800
Query: 813 ------CERRC-------ECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGC-GRCLA 858
CE C C P C G C P CR G+ C C C
Sbjct: 801 PAGGVNCETTCANLAMNFTCTPSS--PCISGCVCAP-GVCR--RGMFNCTYYPCPAVCTI 855
Query: 859 NGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQV 918
G HY + DG YD C L + D D S++ + D +V +
Sbjct: 856 YGDRHYYSFDGLEYDYISDCQVFLIK----SADDSDISVIAQNKKCFDND--IVCSKSVL 909
Query: 919 VSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRN-----------MVLQTTKGLRLLFDGD 967
+S+ + D P + E ++ +V K + +L+D
Sbjct: 910 ISVGDTEIYLND-----TPYKQKQSGFFLENKSTYQLWKAGYYIVVYFPEKDITILWDRK 964
Query: 968 AHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEG 1027
+ + + ++ +L GLCGNF+ S+D N + FG +W + G + E
Sbjct: 965 TTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSWAL-GQCESPDET 1023
Query: 1028 CGPQGCPVCLAEETA-PYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQK-- 1084
P C A + PY E C L + FA+C+ V+ + + + C D C
Sbjct: 1024 IKP-----CEAHQNKFPYAKKE-CSILYS--DIFASCRNVIDVTSFAKNCHEDTCNCNLG 1075
Query: 1085 GDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHC 1121
GD LC S+AAY C G+++ WR+ + C L C
Sbjct: 1076 GDCECLCTSIAAYAYKCCQEGISIH-WRSSTVCSLDC 1111
Score = 255 bits (652), Expect = 2e-67
Identities = 227/841 (26%), Positives = 343/841 (40%), Gaps = 99/841 (11%)
Query: 424 FWADGTCSQWCRCGPGGGSLVCTPASC------GLGEVCGLLPSGQHGCQPVSTAECQAW 477
F G+C C G+ +C LG C ++P+ +G + C+ W
Sbjct: 16 FSPSGSCPYECL----NGAFCSKTGTCDCQIFQALGTRCQIIPNMGNGRDGI----CKTW 67
Query: 478 GDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAV-SYTRSVTL 536
G H+ T DG + F G C Y+ + C +TV V N + +V S RS++L
Sbjct: 68 GQYHFETFDGIYYYFPGNCSYIFAKDCGDLE---PRYTVWVHNSPKCLGSVYSCYRSISL 124
Query: 537 QIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSF 596
N + +++ +G+ + LP + + L+ ++V TT G SLA+DG S
Sbjct: 125 FFSNQEEIRI--YGHEIKKNGISLTLPQTIGQIFIEKLADY-ILVKTTFGFSLAWDGISG 181
Query: 597 VRLRVPAAYAASLCGLCGNYNQDPADDL--------KAVGGKPAGWQVGGAQGCGECVSK 648
+ L++ + CGLCGNYN +DD + + W V +CV
Sbjct: 182 IYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDT-KCVLT 240
Query: 649 PC--PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPG 706
P P+PC+ C ++ P CH + P Y C+ D C+
Sbjct: 241 PSDFPNPCSSGMPAFEAIFFKCQIL--LQFPFLSCHEYIDPYLYIASCVNDLCKTDDDET 298
Query: 707 GLCPAVATYVAACQAAGAQLGEWRRPDF--CPLQCPAHSHYELCGDSCPVSCPSLSAPEG 764
C A Y AC AG + +WR DF C +C + C CP +C G
Sbjct: 299 -YCRAATEYARACSHAGYPIQDWR-DDFPACTDKCDDSFVHRDCISCCPPTCTFEKQCLG 356
Query: 765 CESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGH 824
C +GC C G V+ TC+ + C C G Y +G + E+ C
Sbjct: 357 SNLHCLDGCYCPDGLVMDNGTCISLENCPCGFHGLAYSVGS------KIEQECT------ 404
Query: 825 VTCQEGAACGPHEECRLEDGVQACHATGCG-RCLANGGIHYITLDGRVYDLHGSCSYVLA 883
EC GV C C +C G H+ T DGR Y G C Y+L
Sbjct: 405 -------------ECVCVGGVWNCTEQDCPVQCSVVGDSHFTTFDGRHYSFIGMCQYILV 451
Query: 884 QVCHPKPGDEDFSIVLEKNAAGD------LQRLLVTVA---GQVVSLAQGQQV-TVDGEA 933
+ G + F+I L+K LQ + + + + V+L +G Q+ T +
Sbjct: 452 K----GTGKDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGRGGQILTSPNQG 507
Query: 934 VALPVAVGRVRV-TAEGRNMVLQTTKGLRLLF--DGDAHLLMSIPSPFRGRLCGLCGNFN 990
L G V + T ++L+TT GL++LF DG+ + + + S ++ R GLCG FN
Sbjct: 508 FNLN---GIVEIQTLSSLFILLKTTFGLKILFAIDGE-RIYIQLTSAWKRRTLGLCGTFN 563
Query: 991 GNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEGCGPQGCPVCLAEETAPYESNEAC 1050
GN DDF+ P+G + + AWRV SS P P + ++ Y ++ C
Sbjct: 564 GNIRDDFLSPSGMIEGTPQLHANAWRV--SSTCFAPVHVPVVDPCNINQQNIGYAAH--C 619
Query: 1051 GQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKP 1110
+ Q FA C +SP Y++ C +D C K + LC +LA Y C GV +
Sbjct: 620 DVIH--QELFAPCHIYISPGLYYQLCRHDAC--KCGSSCLCNALAHYAYLCGQHGVPIDF 675
Query: 1111 WRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQ--GVC 1168
SFC + C Y C+ C SC +LS C+ C EGC C + C
Sbjct: 676 RTQISFCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEGKFYEDTLNFC 735
Query: 1169 IPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPG-RVCEVKAEARN 1227
+P+ C C + G + T S C CS+ + + C P +C E +
Sbjct: 736 VPIFHCRCHYRGSVYQPGELIPTP--SGLCQCSNGT-VKCDELATPSAVHICPEGKEYFD 792
Query: 1228 C 1228
C
Sbjct: 793 C 793
Score = 80.5 bits (197), Expect = 1e-14
Identities = 100/440 (22%), Positives = 166/440 (37%), Gaps = 73/440 (16%)
Query: 818 ECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGS 877
+CG G C P EC RC + IT DG L+
Sbjct: 1416 DCGFRGRPVQVNSDICCPEWECPC-------------RCSMLSELSIITFDGNNAALYSM 1462
Query: 878 CSYVLAQVCHPKPGDEDFSIV----LEKNAAGDLQRL------LVTVAGQVVSLAQGQQV 927
SY+L ++ PG+ + + + + +G + L + T +++ ++V
Sbjct: 1463 ASYILVRI----PGEIIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLARKV 1518
Query: 928 TVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHL--LMSIPSPFRGRLC-- 983
VD V LP + + + G V+ T GL + + +HL ++ I FR L
Sbjct: 1519 EVDSIVVPLPFSSQELSIEDSGSMYVITTPAGLIIKW---SHLTGIIDIHFGFRFNLSSY 1575
Query: 984 --GLCGNFNGNWSDDFVLPNGSAASSVETFGA---AWRVPGS----SKGCGEGCGPQGCP 1034
GLCG N + DD + NG+ +++E G +W + S + C C
Sbjct: 1576 TEGLCGICNEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTMRRPVRNCTEHDCS 1635
Query: 1035 VCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSL 1094
C+ L N + F C +SP ++ + + + C +L
Sbjct: 1636 QCI--------------DLLNRR-IFIPCHDKVSPEDFCEKMWINYTYFWN---YECDAL 1677
Query: 1095 AAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTT--RCF 1152
+AY A C + ++ WRT +C L CP Y C R C+ G T+
Sbjct: 1678 SAYVALCNKFDICIQ-WRTPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSCLNLR 1736
Query: 1153 EGCECDDRFLLSQ---GVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCS---CSSSSGL 1206
E C C +L + CIP ++C CT + P + + + + C+ C + +
Sbjct: 1737 EDCVCKVGTILHRPHSAQCIPEKECACT-DSEDQPRTAGEIWNGGIDECTLYKCLENGSI 1795
Query: 1207 TCQAAGC--PPGRVCEVKAE 1224
C P VCE +AE
Sbjct: 1796 IPIEPDCDEEPTPVCEREAE 1815
Score = 77.8 bits (190), Expect = 7e-14
Identities = 87/345 (25%), Positives = 130/345 (37%), Gaps = 46/345 (13%)
Query: 474 CQAWGDPHYVTLDGHRFDFQGTCEYLL-SAPCHGPPLGAENFTVTVANEHRGSQAVSYTR 532
C + +T DG+ Y+L P E ++ A R S
Sbjct: 1441 CSMLSELSIITFDGNNAALYSMASYILVRIPGEIIVAHIEKCSMNQAPSGRISGLCFKKL 1500
Query: 533 SVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFD 592
+VT I H + ++ R RK++VD + V LPF L SG+ V+TT +GL + +
Sbjct: 1501 NVTTPI--HKIIVN-RLARKVEVDSIVVPLPFSSQEL-SIEDSGSMYVITTPAGLIIKWS 1556
Query: 593 G-----DSFVRLRVP-AAYAASLCGLCGNYNQDPADDLKAVGGKPA-----------GWQ 635
D R ++Y LCG+C N+DP DDL+ G W+
Sbjct: 1557 HLTGIIDIHFGFRFNLSSYTEGLCGIC---NEDPDDDLRMQNGTIITNMEDIGLFIESWE 1613
Query: 636 VGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPL-APCHGLVPPAQYFQGC 694
+ + E + CT D I + + PCH V P + +
Sbjct: 1614 I---EKSFEVTMRRPVRNCTEH--------DCSQCIDLLNRRIFIPCHDKVSPEDFCEKM 1662
Query: 695 LLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPV 754
++ + C A++ YVA C + +WR PD+C L CP Y+ C C
Sbjct: 1663 WINYTYFWNYE---CDALSAYVALCNKFDICI-QWRTPDYCSLSCPEGKEYQPCVRPCEA 1718
Query: 755 SCPSLSAPEGCESA--CREGCVCDAGFVL---SGDTCVPVGQCGC 794
G S RE CVC G +L C+P +C C
Sbjct: 1719 RTCLNQWFYGHTSCLNLREDCVCKVGTILHRPHSAQCIPEKECAC 1763
Score = 64.7 bits (156), Expect = 6e-10
Identities = 88/389 (22%), Positives = 139/389 (35%), Gaps = 54/389 (13%)
Query: 61 QGGQGVCLPNYEATCW--LWGDPHYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLTPFT 118
Q +C P +E C + + +FDG +Y+L V G
Sbjct: 1425 QVNSDICCPEWECPCRCSMLSELSIITFDGNNAALYSMASYIL-------VRIPGEIIVA 1477
Query: 119 VTTKNENRGNPAVSYVRVVTVAALGTNISIHKDEIG----KVRVNGVLTALPVSVADGRI 174
K P+ + + L IHK + KV V+ ++ LP S + +
Sbjct: 1478 HIEKCSMNQAPS-GRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQE--L 1534
Query: 175 SVAQGASKALLVADFGLQVSYD---------WNWRVDVTLPSSYHGAVCGLCGNMDRNPN 225
S+ S ++ GL + + + +R ++ SSY +CG+C + +P+
Sbjct: 1535 SIEDSGSMYVITTPAGLIIKWSHLTGIIDIHFGFRFNL---SSYTEGLCGIC---NEDPD 1588
Query: 226 NDQVFPNGTLAPS---IPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGP 282
+D NGT+ + I ++ SW + R C E Q C
Sbjct: 1589 DDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTM---RRPVRNCTEHDCSQ------CID 1639
Query: 283 LAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVVIEDW 342
L F CH V PE F + ++ C AL++YVA C + I+ W
Sbjct: 1640 LL--NRRIFIPCHDKVSPEDFCEKMWINYTYFWNYE---CDALSAYVALCNKFDICIQ-W 1693
Query: 343 RAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVL---SA 399
R C ++CPE Y+ C PC A C E C C G +L +
Sbjct: 1694 RTPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSCLN-LREDCVCKVGTILHRPHS 1752
Query: 400 DRCVPLNNGCGCWANGTYHEAGSEFWADG 428
+C+P C C + E W G
Sbjct: 1753 AQCIP-EKECACTDSEDQPRTAGEIWNGG 1780
Score = 47.0 bits (110), Expect = 1e-04
Identities = 50/204 (24%), Positives = 83/204 (40%), Gaps = 22/204 (10%)
Query: 1193 DCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGA 1252
+C CS + CQ G C++ N G+C + TFDG
Sbjct: 25 ECLNGAFCSKTGTCDCQIFQAL-GTRCQIIPNMGN--GRDGICKTWGQYHFETFDGIYYY 81
Query: 1253 TTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVGQVH-------IFFQDGMVTL 1305
Y + C L+ P Y V H + +G V+ +FF +
Sbjct: 82 FPGNCSYIFAKDCGDLE---PRYTVWV-----HNSPKCLGSVYSCYRSISLFFSNQEEIR 133
Query: 1306 TPNKGVWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQV-WLGANGKVAVIVSNDH 1364
+ NG+ + LP + + + + + D +LV+ G + W G +G + + +S DH
Sbjct: 134 IYGHEIKKNGISLTLP-QTIGQIFIEKLAD-YILVKTTFGFSLAWDGISG-IYLKLSEDH 190
Query: 1365 AGKLCGACGNFDGDQTNDWHDSQE 1388
GK CG CGN++ Q++D+ QE
Sbjct: 191 KGKSCGLCGNYNDIQSDDFIILQE 214
>gi|239755545 PREDICTED: otogelin isoform 1 [Homo sapiens]
Length = 2852
Score = 297 bits (761), Expect = 4e-80
Identities = 305/1178 (25%), Positives = 452/1178 (38%), Gaps = 205/1178 (17%)
Query: 69 PNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLTPFTVTTKNENR-G 127
P ++ C WG H +FDG + G +Y L +G F++ N+ + G
Sbjct: 73 PERDSICRAWGQHHVETFDGLYYYLSGKGSYTL-----VGRHEPEGQSFSIQVHNDPQCG 127
Query: 128 NPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVA 187
+ + R V++ +G IH + +V G+ LP + R+ Q A ++
Sbjct: 128 SSPYTCSRAVSLFFVGEQ-EIHLAK--EVTHGGMRVQLPHVMGSARLQ--QLAGYVIVRH 182
Query: 188 DFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWR 247
+++D V + + G GLCGN + +P +D V +G L + + SW+
Sbjct: 183 QSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ 242
Query: 248 --APGWDP------LCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVP 299
AP P L C P + EQ E L P PF CHA+V
Sbjct: 243 EQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEAL-----LRP----PFDACHAYVS 293
Query: 300 PESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVVIEDWRAQV-GCEITCPENSH- 357
P F C D+C GD C+ALA Y AC AG ++ WR Q+ C + C E +
Sbjct: 294 PLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFT 353
Query: 358 YEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTY 417
Y C CPASC P + E CV+GC C G + CV C C +GT
Sbjct: 354 YNECIACCPASC---HPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE-CPCEFHGTL 409
Query: 418 HEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAW 477
+ GS D C+ C C G C+ A C AEC
Sbjct: 410 YPPGSVVKED--CNT-CTC--TSGKWECSTAVC--------------------PAECSVT 444
Query: 478 GDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTL 536
GD H+ T DG R+ F TC+Y+L+ + FTVT+ N G +Q + +SV++
Sbjct: 445 GDIHFTTFDGRRYTFPATCQYILA-----KSRSSGTFTVTLQNAPCGLNQDGACVQSVSV 499
Query: 537 QIY---NHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDG 593
++ +TL+ L D + P+ D+ LS + V T G+ + +D
Sbjct: 500 ILHQDPRRQVTLTQAGD-VLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDR 558
Query: 594 DSF-VRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQGCGE 644
+ + L+V + GLCG +N + DD + G P W+ A C
Sbjct: 559 EGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA--CSP 616
Query: 645 CVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGH 704
VS PC Q + AC V+ T APC + P YF+ C DAC+ G
Sbjct: 617 LVSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDACRC-GQ 673
Query: 705 PGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEG 764
P LC +A Y C+ G + R C L C A Y C C +C L++PE
Sbjct: 674 P-CLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEA 732
Query: 765 C---------ESACREGCVC--DAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPG--- 810
C C EGC C D D CVP QC C G YP G+ P
Sbjct: 733 CGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGH 792
Query: 811 -------PECERRCECG--PGGHV-----------------TCQE--------------- 829
C+ R P G V TC++
Sbjct: 793 CHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLS 852
Query: 830 -----------GAACGPHEECRL----------EDGVQACHATGCGR------------- 855
G AC EEC + + CH C R
Sbjct: 853 GCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPCAST 912
Query: 856 CLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEK---NAAGDLQRLLV 912
C A G HY T DG +D G+C L + D FS+++E ++G + R
Sbjct: 913 CTAYGDRHYRTFDGLPFDFVGACKVHLVK----STSDVSFSVIVENVNCYSSGMICR--- 965
Query: 913 TVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGR-------NMVLQTTKGLRLLFD 965
+ +S+ G + V + P + E +V + + LL+D
Sbjct: 966 ----KFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWD 1021
Query: 966 GDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCG 1025
+ + ++G+L GLCGNF+ ++ P ++ + FG++W ++ C
Sbjct: 1022 QRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSW----AAVECP 1077
Query: 1026 EGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDL--CAQ 1083
+ P+ +C+ + + C L + F C V+ + ++ C+ D C+Q
Sbjct: 1078 DTLDPR--DMCVLNPLREPFAKKECSILLSE--VFEICHPVVDVTWFYSNCLTDTCGCSQ 1133
Query: 1084 KGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHC 1121
GD C S++AY C GVAV WRT CP C
Sbjct: 1134 GGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1170
Score = 254 bits (649), Expect = 4e-67
Identities = 233/821 (28%), Positives = 317/821 (38%), Gaps = 90/821 (10%)
Query: 440 GGSLVCTPASCGLGEVCGLLPSGQ--HGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCE 497
GG V PA C P Q + P + C+AWG H T DG + G
Sbjct: 44 GGECV-HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGS 102
Query: 498 YLLSAPCHGPPLGAENFTVTVANEHR-GSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD 556
Y L H P ++F++ V N+ + GS + +R+V+L +++
Sbjct: 103 YTLVGR-HEPE--GQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQ---EIHLAKEVTHG 156
Query: 557 GVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNY 616
G+ V LP + S L+G V+V S +LA+DG S V +++ GLCGN
Sbjct: 157 GMRVQLPHVMGSARLQQLAGY-VIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNN 215
Query: 617 NQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCT------PEQQESFGGPDACGV 670
N DP DDL GK V E P P T P Q++ G GV
Sbjct: 216 NADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQ--GV 273
Query: 671 ISATDGPLAP----CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQL 726
+ L P CH V P + C D CQ G C A+A Y AC AG L
Sbjct: 274 YEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 333
Query: 727 GEWRRP-DFCPLQCPAHSH-YELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGD 784
WR C + C + Y C CP SC ++ E AC +GC C G +
Sbjct: 334 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDG 393
Query: 785 TCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDG 844
CV +C C G YP PG + C C G
Sbjct: 394 GCVAPAECPCEFHGTLYP------PGSVVKEDCNT-------------------CTCTSG 428
Query: 845 VQACHATGC-GRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNA 903
C C C G IH+ T DGR Y +C Y+LA+ F++ L+
Sbjct: 429 KWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAK----SRSSGTFTVTLQNAP 484
Query: 904 AG---------DLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVL 954
G + +L + V+L Q V + + +P ++ L
Sbjct: 485 CGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFL 544
Query: 955 Q--TTKGLRLLFDGDA-HLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETF 1011
+ T G+R+L+D + L + + + GLCG FNGN DDF+ P G S+ + F
Sbjct: 545 RVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLF 604
Query: 1012 GAAWRVPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSE 1071
G +W+ + G C V L + A Y S +AC L FA C A LSP
Sbjct: 605 GNSWKTLSACSPLVSGSPLDPCDVHL--QAASY-SVQACSVLTGEM--FAPCSAFLSPVP 659
Query: 1072 YFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICT 1131
YF QC D C + + LC +LA Y C+ G+ V C L C A YS C
Sbjct: 660 YFEQCRRDAC--RCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCV 717
Query: 1132 RTCQGSCAALSGLTGC---------TTRCFEGCEC-DDRFLLSQG-VCIPVQDCGCTHNG 1180
C +C L+ C C EGC C D +L +Q +C+P C C G
Sbjct: 718 APCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQG 777
Query: 1181 RYLPVNSSLLTSDCSERCSCSS---SSGLTCQAAGCPPGRV 1218
P S + S C C S AA CP G+V
Sbjct: 778 VDYPPGDSDIPS--LGHCHCKDGVMSCDSRAPAAACPAGQV 816
Score = 161 bits (407), Expect = 5e-39
Identities = 154/588 (26%), Positives = 227/588 (38%), Gaps = 47/588 (7%)
Query: 816 RCECGPGGHVTCQEGAACGPHE--ECRLEDGV----QACHATGCGR---CLANGGIHYIT 866
R +C P +C G C +CR + Q + G R C A G H T
Sbjct: 30 RAKCAPSYLFSCFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVET 89
Query: 867 LDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRL-------LVTVAGQVV 919
DG Y L G SY L V +P + FSI + + L V Q +
Sbjct: 90 FDGLYYYLSGKGSYTL--VGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEI 147
Query: 920 SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFR 979
LA+ +VT G V LP +G R+ ++++ L +DG + + + +
Sbjct: 148 HLAK--EVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELL 205
Query: 980 GRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEGCGPQGCPVCLAE 1039
G GLCGN N + DD V +G V F +W+ ++ G P CL +
Sbjct: 206 GWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQ 265
Query: 1040 ETAPYES-NEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYT 1098
+ E C L P PF C A +SP + C DLC GD A CR+LA Y
Sbjct: 266 NPGTMQGVYEQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYA 323
Query: 1099 AACQAAGVAVKPWRTD-SFCPLHCPAHSH-YSICTRTCQGSCAALSGLTGCTTRCFEGCE 1156
AC AG ++ WRT C +HC + Y+ C C SC + C +GC
Sbjct: 324 RACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCY 383
Query: 1157 CDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPG 1216
C + + G C+ +C C +G P S++ DC+ C+C+S C A CP
Sbjct: 384 CPNGLIFEDGGCVAPAECPCEFHGTLYP-PGSVVKEDCN-TCTCTSGK-WECSTAVCP-- 438
Query: 1217 RVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYR 1276
AE C ++ + TTFDG R + Y L+ T+
Sbjct: 439 ------AE----------CSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQN 482
Query: 1277 VVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDG 1336
+ ++V + VTLT V + +P + + R
Sbjct: 483 APCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSV 542
Query: 1337 SLLVRQKAGVQVWLGANG-KVAVIVSNDHAGKLCGACGNFDGDQTNDW 1383
L VR GV+V G ++ + V G CG F+G+ +D+
Sbjct: 543 FLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDF 590
Score = 94.0 bits (232), Expect = 9e-19
Identities = 118/502 (23%), Positives = 190/502 (37%), Gaps = 87/502 (17%)
Query: 755 SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLH----DGRYYPLGEVFYPG 810
S P+LS EG A + + TCVP+ + C+ +G+ + + +
Sbjct: 1953 SAPALSIVEGLAEALATTTEAN-----TSTTCVPIAEQDCVRHICLEGQLIRVNQSQHC- 2006
Query: 811 PECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGR 870
P+ CG G G C P EC AC RC + ++T DG
Sbjct: 2007 PQGAAPPRCGILGLAVRVGGDRCCPLWEC-------AC------RCSIFPDLSFVTFDGS 2053
Query: 871 VYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRL-----------LVTVAGQVV 919
L Y+L+Q DE ++ + + +L L + +A QV
Sbjct: 2054 HVALFKEAIYILSQ-----SPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVT 2108
Query: 920 SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLM---SIPS 976
++VTVD + V PV+ R+ G ++ T +++ + + L++ S S
Sbjct: 2109 IDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTS 2168
Query: 977 PFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVET---FGAAWRVPGSSKGCGE------G 1027
+G GLCG +G+ ++D L +GS E F +W+VP S G+
Sbjct: 2169 KAQGH--GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDS 2226
Query: 1028 CGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDK 1087
C C CL + AC + P+ + C+ + ++Y +Q
Sbjct: 2227 CATTDCSPCL--RMVSNRTFSACHRFVPPE---SFCELWIRDTKYVQQP----------- 2270
Query: 1088 AFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTG- 1146
C +L Y A C V ++ WR +CP C + S Y C C+ G+ G
Sbjct: 2271 ---CVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGP 2326
Query: 1147 -----CTTRCFEGCECDDRFLLSQ---GVCIPVQDCGCTHN---GRYLPVNSSLLTSDCS 1195
C EGC C + +L + +CIP C CT + R L + S C
Sbjct: 2327 LDPEHCQV-LGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCC 2385
Query: 1196 ERCSCSSSSGLTCQAAGCPPGR 1217
+ C + + GCP R
Sbjct: 2386 QH-QCQAPDTIVPVDLGCPSPR 2406
Score = 84.7 bits (208), Expect = 6e-16
Identities = 105/415 (25%), Positives = 157/415 (37%), Gaps = 79/415 (19%)
Query: 447 PASCGLGEVCGL-LPSGQHGCQPV--STAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAP 503
P CG + GL + G C P+ C + D +VT DG Y+LS
Sbjct: 2012 PPRCG---ILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS 2068
Query: 504 -----------CHGPPLGAEN---FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSAR- 548
C LG N F + + N VT+ +N +T+ +
Sbjct: 2069 PDEMLTVHVLDCKSANLGHLNWPPFCLVMLN------MTHLAHQVTIDRFNRKVTVDLQP 2122
Query: 549 -WPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRL----RVPA 603
WP + F+++ H ++ + T S + + + S + + +
Sbjct: 2123 VWPPVSRYG-------FRIEDTGHMYM------ILTPSDIQIQWLHSSGLMIVEASKTSK 2169
Query: 604 AYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECV-SKPCPSPCTPEQQESF 662
A LCG+C D A+DL G VGGA+ + S PS T Q F
Sbjct: 2170 AQGHGLCGICDG---DAANDLTLKDGSV----VGGAEDPAPFLDSWQVPSSLTSVGQTRF 2222
Query: 663 GGPDACGVISAT-------DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATY 715
PD+C + + + CH VPP + + + D VQ C A+ Y
Sbjct: 2223 R-PDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVY 2277
Query: 716 VAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSC--PVSCP----SLSAPEGCESAC 769
VA C + EWRR D+CP C + S Y+ C +C P +C PE C+
Sbjct: 2278 VAMCHKFHVCI-EWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQ-VL 2335
Query: 770 REGCVCDAGFVL---SGDTCVPVGQCGCLHD-GRYYPLGEVFYPGPE--CERRCE 818
EGCVC G +L C+P +C C G LGE + C+ +C+
Sbjct: 2336 GEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQ 2390
Score = 80.9 bits (198), Expect = 8e-15
Identities = 77/315 (24%), Positives = 117/315 (37%), Gaps = 43/315 (13%)
Query: 46 PCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTG 105
PCH C ++G L +TC +GD HY +FDG FDF G C L
Sbjct: 891 PCHTCVC-------QRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHL---- 939
Query: 106 CLGVSTQGLTPFTVTTKNENRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTAL 165
V + F+V +N N + + + +++ +G ++ + D+ G
Sbjct: 940 ---VKSTSDVSFSVIVENVNCYSSGMICRKFISI-NVGNSLIVFDDDSG--------NPS 987
Query: 166 PVSVADGRISVAQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDR 222
P S D + V + F + + +D V V + G + GLCGN D
Sbjct: 988 PESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDL 1047
Query: 223 NPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSC---PTCPEDRLEQYEGPGF 279
N+ P + +G SW A EC + C + L +
Sbjct: 1048 KTINEMRTPENLELTNPQEFGSSWAAV--------ECPDTLDPRDMCVLNPLREPFAKKE 1099
Query: 280 CGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDHDILCKALASYVAACQAAGV 337
C L F CH V F+ C+ D C GGD + C ++++Y C GV
Sbjct: 1100 CSILLSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGV 1156
Query: 338 VIEDWRAQVGCEITC 352
+ DWR C C
Sbjct: 1157 AV-DWRTPRLCPYDC 1170
Score = 64.3 bits (155), Expect = 8e-10
Identities = 112/432 (25%), Positives = 157/432 (36%), Gaps = 65/432 (15%)
Query: 67 CLPNYEATCW--LWGDPHYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLTPFTVTTKNE 124
C P +E C ++ D + +FDG Y+L+ + + LT + K+
Sbjct: 2029 CCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS-----PDEMLTVHVLDCKSA 2083
Query: 125 NRGN---PAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGAS 181
N G+ P V ++ + L ++I + KV V+ PVS RI
Sbjct: 2084 NLGHLNWPPFCLV-MLNMTHLAHQVTIDRFN-RKVTVDLQPVWPPVSRYGFRIEDTGHMY 2141
Query: 182 KALLVADFGLQVSYDWNWR-VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTL----- 235
L +D +Q + V+ + S G GLCG D + ND +G++
Sbjct: 2142 MILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLKDGSVVGGAE 2199
Query: 236 --APSIPIWG--GSWRAPGWDPLCWDECRGS-CPTCPEDRLEQYEGPGFCGPLAPGTGGP 290
AP + W S + G D C + C C L +
Sbjct: 2200 DPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPC----------------LRMVSNRT 2243
Query: 291 FTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVVIEDWRAQVGCEI 350
F+ CH VPPESF + + D C AL YVA C V IE WR C
Sbjct: 2244 FSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCIE-WRRSDYCPF 2298
Query: 351 TCPENSHYEVCGPPC--PASCPSP--APLTTPAVCEGPCVEGCQCDAGFVL---SADRCV 403
C +S Y+ C C P +C PL P C+ EGC C G +L + C+
Sbjct: 2299 LCSSDSTYQACVTACEPPKTCQDGILGPL-DPEHCQ-VLGEGCVCSEGTILHRRHSALCI 2356
Query: 404 PLNNGCGCWANGTYHEAGSEFW---ADGTCSQWCRCGP-----GGGSLVCTPASC-GLGE 454
P C C + A E W G C C+ G P SC GE
Sbjct: 2357 P-EAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGE 2415
Query: 455 VCGLLPSGQHGC 466
V LLP+ C
Sbjct: 2416 VALLLPTKDPCC 2427
Score = 32.7 bits (73), Expect = 2.5
Identities = 26/96 (27%), Positives = 33/96 (34%), Gaps = 17/96 (17%)
Query: 1121 CPAHSHYSICT-----------RTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCI 1169
CPA + C+ RTC+ LS C GC C L C
Sbjct: 811 CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLS--VSARGPCLSGCACPQGLLRHGDACF 868
Query: 1170 PVQDCGCTHNGR-YLPVNSSLLTSDCSERCSCSSSS 1204
++C CT G+ Y P + S C C C S
Sbjct: 869 LPEECPCTWKGKEYFP--GDQVMSPC-HTCVCQRGS 901
>gi|239755543 PREDICTED: otogelin isoform 2 [Homo sapiens]
Length = 2924
Score = 297 bits (761), Expect = 4e-80
Identities = 305/1178 (25%), Positives = 452/1178 (38%), Gaps = 205/1178 (17%)
Query: 69 PNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLTPFTVTTKNENR-G 127
P ++ C WG H +FDG + G +Y L +G F++ N+ + G
Sbjct: 145 PERDSICRAWGQHHVETFDGLYYYLSGKGSYTL-----VGRHEPEGQSFSIQVHNDPQCG 199
Query: 128 NPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVA 187
+ + R V++ +G IH + +V G+ LP + R+ Q A ++
Sbjct: 200 SSPYTCSRAVSLFFVGEQ-EIHLAK--EVTHGGMRVQLPHVMGSARLQ--QLAGYVIVRH 254
Query: 188 DFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWR 247
+++D V + + G GLCGN + +P +D V +G L + + SW+
Sbjct: 255 QSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ 314
Query: 248 --APGWDP------LCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVP 299
AP P L C P + EQ E L P PF CHA+V
Sbjct: 315 EQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEAL-----LRP----PFDACHAYVS 365
Query: 300 PESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVVIEDWRAQV-GCEITCPENSH- 357
P F C D+C GD C+ALA Y AC AG ++ WR Q+ C + C E +
Sbjct: 366 PLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFT 425
Query: 358 YEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTY 417
Y C CPASC P + E CV+GC C G + CV C C +GT
Sbjct: 426 YNECIACCPASC---HPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE-CPCEFHGTL 481
Query: 418 HEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAW 477
+ GS D C+ C C G C+ A C AEC
Sbjct: 482 YPPGSVVKED--CNT-CTC--TSGKWECSTAVC--------------------PAECSVT 516
Query: 478 GDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTL 536
GD H+ T DG R+ F TC+Y+L+ + FTVT+ N G +Q + +SV++
Sbjct: 517 GDIHFTTFDGRRYTFPATCQYILA-----KSRSSGTFTVTLQNAPCGLNQDGACVQSVSV 571
Query: 537 QIY---NHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDG 593
++ +TL+ L D + P+ D+ LS + V T G+ + +D
Sbjct: 572 ILHQDPRRQVTLTQAGD-VLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDR 630
Query: 594 DSF-VRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQGCGE 644
+ + L+V + GLCG +N + DD + G P W+ A C
Sbjct: 631 EGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA--CSP 688
Query: 645 CVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGH 704
VS PC Q + AC V+ T APC + P YF+ C DAC+ G
Sbjct: 689 LVSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDACRC-GQ 745
Query: 705 PGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEG 764
P LC +A Y C+ G + R C L C A Y C C +C L++PE
Sbjct: 746 P-CLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEA 804
Query: 765 C---------ESACREGCVC--DAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPG--- 810
C C EGC C D D CVP QC C G YP G+ P
Sbjct: 805 CGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGH 864
Query: 811 -------PECERRCECG--PGGHV-----------------TCQE--------------- 829
C+ R P G V TC++
Sbjct: 865 CHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLS 924
Query: 830 -----------GAACGPHEECRL----------EDGVQACHATGCGR------------- 855
G AC EEC + + CH C R
Sbjct: 925 GCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPCAST 984
Query: 856 CLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEK---NAAGDLQRLLV 912
C A G HY T DG +D G+C L + D FS+++E ++G + R
Sbjct: 985 CTAYGDRHYRTFDGLPFDFVGACKVHLVK----STSDVSFSVIVENVNCYSSGMICR--- 1037
Query: 913 TVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGR-------NMVLQTTKGLRLLFD 965
+ +S+ G + V + P + E +V + + LL+D
Sbjct: 1038 ----KFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWD 1093
Query: 966 GDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCG 1025
+ + ++G+L GLCGNF+ ++ P ++ + FG++W ++ C
Sbjct: 1094 QRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSW----AAVECP 1149
Query: 1026 EGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDL--CAQ 1083
+ P+ +C+ + + C L + F C V+ + ++ C+ D C+Q
Sbjct: 1150 DTLDPR--DMCVLNPLREPFAKKECSILLSE--VFEICHPVVDVTWFYSNCLTDTCGCSQ 1205
Query: 1084 KGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHC 1121
GD C S++AY C GVAV WRT CP C
Sbjct: 1206 GGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1242
Score = 254 bits (649), Expect = 4e-67
Identities = 233/821 (28%), Positives = 317/821 (38%), Gaps = 90/821 (10%)
Query: 440 GGSLVCTPASCGLGEVCGLLPSGQ--HGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCE 497
GG V PA C P Q + P + C+AWG H T DG + G
Sbjct: 116 GGECV-HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGS 174
Query: 498 YLLSAPCHGPPLGAENFTVTVANEHR-GSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD 556
Y L H P ++F++ V N+ + GS + +R+V+L +++
Sbjct: 175 YTLVGR-HEPE--GQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQ---EIHLAKEVTHG 228
Query: 557 GVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNY 616
G+ V LP + S L+G V+V S +LA+DG S V +++ GLCGN
Sbjct: 229 GMRVQLPHVMGSARLQQLAGY-VIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNN 287
Query: 617 NQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCT------PEQQESFGGPDACGV 670
N DP DDL GK V E P P T P Q++ G GV
Sbjct: 288 NADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQ--GV 345
Query: 671 ISATDGPLAP----CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQL 726
+ L P CH V P + C D CQ G C A+A Y AC AG L
Sbjct: 346 YEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 405
Query: 727 GEWRRP-DFCPLQCPAHSH-YELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGD 784
WR C + C + Y C CP SC ++ E AC +GC C G +
Sbjct: 406 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDG 465
Query: 785 TCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDG 844
CV +C C G YP PG + C C G
Sbjct: 466 GCVAPAECPCEFHGTLYP------PGSVVKEDCNT-------------------CTCTSG 500
Query: 845 VQACHATGC-GRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNA 903
C C C G IH+ T DGR Y +C Y+LA+ F++ L+
Sbjct: 501 KWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAK----SRSSGTFTVTLQNAP 556
Query: 904 AG---------DLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVL 954
G + +L + V+L Q V + + +P ++ L
Sbjct: 557 CGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFL 616
Query: 955 Q--TTKGLRLLFDGDA-HLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETF 1011
+ T G+R+L+D + L + + + GLCG FNGN DDF+ P G S+ + F
Sbjct: 617 RVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLF 676
Query: 1012 GAAWRVPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSE 1071
G +W+ + G C V L + A Y S +AC L FA C A LSP
Sbjct: 677 GNSWKTLSACSPLVSGSPLDPCDVHL--QAASY-SVQACSVLTGEM--FAPCSAFLSPVP 731
Query: 1072 YFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICT 1131
YF QC D C + + LC +LA Y C+ G+ V C L C A YS C
Sbjct: 732 YFEQCRRDAC--RCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCV 789
Query: 1132 RTCQGSCAALSGLTGC---------TTRCFEGCEC-DDRFLLSQG-VCIPVQDCGCTHNG 1180
C +C L+ C C EGC C D +L +Q +C+P C C G
Sbjct: 790 APCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQG 849
Query: 1181 RYLPVNSSLLTSDCSERCSCSS---SSGLTCQAAGCPPGRV 1218
P S + S C C S AA CP G+V
Sbjct: 850 VDYPPGDSDIPS--LGHCHCKDGVMSCDSRAPAAACPAGQV 888
Score = 161 bits (407), Expect = 5e-39
Identities = 154/588 (26%), Positives = 227/588 (38%), Gaps = 47/588 (7%)
Query: 816 RCECGPGGHVTCQEGAACGPHE--ECRLEDGV----QACHATGCGR---CLANGGIHYIT 866
R +C P +C G C +CR + Q + G R C A G H T
Sbjct: 102 RAKCAPSYLFSCFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVET 161
Query: 867 LDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRL-------LVTVAGQVV 919
DG Y L G SY L V +P + FSI + + L V Q +
Sbjct: 162 FDGLYYYLSGKGSYTL--VGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEI 219
Query: 920 SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFR 979
LA+ +VT G V LP +G R+ ++++ L +DG + + + +
Sbjct: 220 HLAK--EVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELL 277
Query: 980 GRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEGCGPQGCPVCLAE 1039
G GLCGN N + DD V +G V F +W+ ++ G P CL +
Sbjct: 278 GWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQ 337
Query: 1040 ETAPYES-NEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYT 1098
+ E C L P PF C A +SP + C DLC GD A CR+LA Y
Sbjct: 338 NPGTMQGVYEQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYA 395
Query: 1099 AACQAAGVAVKPWRTD-SFCPLHCPAHSH-YSICTRTCQGSCAALSGLTGCTTRCFEGCE 1156
AC AG ++ WRT C +HC + Y+ C C SC + C +GC
Sbjct: 396 RACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCY 455
Query: 1157 CDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPG 1216
C + + G C+ +C C +G P S++ DC+ C+C+S C A CP
Sbjct: 456 CPNGLIFEDGGCVAPAECPCEFHGTLYP-PGSVVKEDCN-TCTCTSGK-WECSTAVCP-- 510
Query: 1217 RVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYR 1276
AE C ++ + TTFDG R + Y L+ T+
Sbjct: 511 ------AE----------CSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQN 554
Query: 1277 VVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDG 1336
+ ++V + VTLT V + +P + + R
Sbjct: 555 APCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSV 614
Query: 1337 SLLVRQKAGVQVWLGANG-KVAVIVSNDHAGKLCGACGNFDGDQTNDW 1383
L VR GV+V G ++ + V G CG F+G+ +D+
Sbjct: 615 FLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDF 662
Score = 94.0 bits (232), Expect = 9e-19
Identities = 118/502 (23%), Positives = 190/502 (37%), Gaps = 87/502 (17%)
Query: 755 SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLH----DGRYYPLGEVFYPG 810
S P+LS EG A + + TCVP+ + C+ +G+ + + +
Sbjct: 2025 SAPALSIVEGLAEALATTTEAN-----TSTTCVPIAEQDCVRHICLEGQLIRVNQSQHC- 2078
Query: 811 PECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGR 870
P+ CG G G C P EC AC RC + ++T DG
Sbjct: 2079 PQGAAPPRCGILGLAVRVGGDRCCPLWEC-------AC------RCSIFPDLSFVTFDGS 2125
Query: 871 VYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRL-----------LVTVAGQVV 919
L Y+L+Q DE ++ + + +L L + +A QV
Sbjct: 2126 HVALFKEAIYILSQ-----SPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVT 2180
Query: 920 SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLM---SIPS 976
++VTVD + V PV+ R+ G ++ T +++ + + L++ S S
Sbjct: 2181 IDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTS 2240
Query: 977 PFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVET---FGAAWRVPGSSKGCGE------G 1027
+G GLCG +G+ ++D L +GS E F +W+VP S G+
Sbjct: 2241 KAQGH--GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDS 2298
Query: 1028 CGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDK 1087
C C CL + AC + P+ + C+ + ++Y +Q
Sbjct: 2299 CATTDCSPCL--RMVSNRTFSACHRFVPPE---SFCELWIRDTKYVQQP----------- 2342
Query: 1088 AFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTG- 1146
C +L Y A C V ++ WR +CP C + S Y C C+ G+ G
Sbjct: 2343 ---CVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGP 2398
Query: 1147 -----CTTRCFEGCECDDRFLLSQ---GVCIPVQDCGCTHN---GRYLPVNSSLLTSDCS 1195
C EGC C + +L + +CIP C CT + R L + S C
Sbjct: 2399 LDPEHCQV-LGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCC 2457
Query: 1196 ERCSCSSSSGLTCQAAGCPPGR 1217
+ C + + GCP R
Sbjct: 2458 QH-QCQAPDTIVPVDLGCPSPR 2478
Score = 84.7 bits (208), Expect = 6e-16
Identities = 105/415 (25%), Positives = 157/415 (37%), Gaps = 79/415 (19%)
Query: 447 PASCGLGEVCGL-LPSGQHGCQPV--STAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAP 503
P CG + GL + G C P+ C + D +VT DG Y+LS
Sbjct: 2084 PPRCG---ILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS 2140
Query: 504 -----------CHGPPLGAEN---FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSAR- 548
C LG N F + + N VT+ +N +T+ +
Sbjct: 2141 PDEMLTVHVLDCKSANLGHLNWPPFCLVMLN------MTHLAHQVTIDRFNRKVTVDLQP 2194
Query: 549 -WPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRL----RVPA 603
WP + F+++ H ++ + T S + + + S + + +
Sbjct: 2195 VWPPVSRYG-------FRIEDTGHMYM------ILTPSDIQIQWLHSSGLMIVEASKTSK 2241
Query: 604 AYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECV-SKPCPSPCTPEQQESF 662
A LCG+C D A+DL G VGGA+ + S PS T Q F
Sbjct: 2242 AQGHGLCGICDG---DAANDLTLKDGSV----VGGAEDPAPFLDSWQVPSSLTSVGQTRF 2294
Query: 663 GGPDACGVISAT-------DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATY 715
PD+C + + + CH VPP + + + D VQ C A+ Y
Sbjct: 2295 R-PDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVY 2349
Query: 716 VAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSC--PVSCP----SLSAPEGCESAC 769
VA C + EWRR D+CP C + S Y+ C +C P +C PE C+
Sbjct: 2350 VAMCHKFHVCI-EWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQ-VL 2407
Query: 770 REGCVCDAGFVL---SGDTCVPVGQCGCLHD-GRYYPLGEVFYPGPE--CERRCE 818
EGCVC G +L C+P +C C G LGE + C+ +C+
Sbjct: 2408 GEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQ 2462
Score = 80.9 bits (198), Expect = 8e-15
Identities = 77/315 (24%), Positives = 117/315 (37%), Gaps = 43/315 (13%)
Query: 46 PCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTG 105
PCH C ++G L +TC +GD HY +FDG FDF G C L
Sbjct: 963 PCHTCVC-------QRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHL---- 1011
Query: 106 CLGVSTQGLTPFTVTTKNENRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTAL 165
V + F+V +N N + + + +++ +G ++ + D+ G
Sbjct: 1012 ---VKSTSDVSFSVIVENVNCYSSGMICRKFISI-NVGNSLIVFDDDSG--------NPS 1059
Query: 166 PVSVADGRISVAQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDR 222
P S D + V + F + + +D V V + G + GLCGN D
Sbjct: 1060 PESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDL 1119
Query: 223 NPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSC---PTCPEDRLEQYEGPGF 279
N+ P + +G SW A EC + C + L +
Sbjct: 1120 KTINEMRTPENLELTNPQEFGSSWAAV--------ECPDTLDPRDMCVLNPLREPFAKKE 1171
Query: 280 CGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDHDILCKALASYVAACQAAGV 337
C L F CH V F+ C+ D C GGD + C ++++Y C GV
Sbjct: 1172 CSILLSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGV 1228
Query: 338 VIEDWRAQVGCEITC 352
+ DWR C C
Sbjct: 1229 AV-DWRTPRLCPYDC 1242
Score = 64.3 bits (155), Expect = 8e-10
Identities = 112/432 (25%), Positives = 157/432 (36%), Gaps = 65/432 (15%)
Query: 67 CLPNYEATCW--LWGDPHYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLTPFTVTTKNE 124
C P +E C ++ D + +FDG Y+L+ + + LT + K+
Sbjct: 2101 CCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS-----PDEMLTVHVLDCKSA 2155
Query: 125 NRGN---PAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGAS 181
N G+ P V ++ + L ++I + KV V+ PVS RI
Sbjct: 2156 NLGHLNWPPFCLV-MLNMTHLAHQVTIDRFN-RKVTVDLQPVWPPVSRYGFRIEDTGHMY 2213
Query: 182 KALLVADFGLQVSYDWNWR-VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTL----- 235
L +D +Q + V+ + S G GLCG D + ND +G++
Sbjct: 2214 MILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLKDGSVVGGAE 2271
Query: 236 --APSIPIWG--GSWRAPGWDPLCWDECRGS-CPTCPEDRLEQYEGPGFCGPLAPGTGGP 290
AP + W S + G D C + C C L +
Sbjct: 2272 DPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPC----------------LRMVSNRT 2315
Query: 291 FTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVVIEDWRAQVGCEI 350
F+ CH VPPESF + + D C AL YVA C V IE WR C
Sbjct: 2316 FSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCIE-WRRSDYCPF 2370
Query: 351 TCPENSHYEVCGPPC--PASCPSP--APLTTPAVCEGPCVEGCQCDAGFVL---SADRCV 403
C +S Y+ C C P +C PL P C+ EGC C G +L + C+
Sbjct: 2371 LCSSDSTYQACVTACEPPKTCQDGILGPL-DPEHCQ-VLGEGCVCSEGTILHRRHSALCI 2428
Query: 404 PLNNGCGCWANGTYHEAGSEFW---ADGTCSQWCRCGP-----GGGSLVCTPASC-GLGE 454
P C C + A E W G C C+ G P SC GE
Sbjct: 2429 P-EAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGE 2487
Query: 455 VCGLLPSGQHGC 466
V LLP+ C
Sbjct: 2488 VALLLPTKDPCC 2499
Score = 32.7 bits (73), Expect = 2.5
Identities = 26/96 (27%), Positives = 33/96 (34%), Gaps = 17/96 (17%)
Query: 1121 CPAHSHYSICT-----------RTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCI 1169
CPA + C+ RTC+ LS C GC C L C
Sbjct: 883 CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLS--VSARGPCLSGCACPQGLLRHGDACF 940
Query: 1170 PVQDCGCTHNGR-YLPVNSSLLTSDCSERCSCSSSS 1204
++C CT G+ Y P + S C C C S
Sbjct: 941 LPEECPCTWKGKEYFP--GDQVMSPC-HTCVCQRGS 973
>gi|239749989 PREDICTED: otogelin isoform 2 [Homo sapiens]
Length = 2852
Score = 297 bits (761), Expect = 4e-80
Identities = 305/1178 (25%), Positives = 452/1178 (38%), Gaps = 205/1178 (17%)
Query: 69 PNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLTPFTVTTKNENR-G 127
P ++ C WG H +FDG + G +Y L +G F++ N+ + G
Sbjct: 73 PERDSICRAWGQHHVETFDGLYYYLSGKGSYTL-----VGRHEPEGQSFSIQVHNDPQCG 127
Query: 128 NPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVA 187
+ + R V++ +G IH + +V G+ LP + R+ Q A ++
Sbjct: 128 SSPYTCSRAVSLFFVGEQ-EIHLAK--EVTHGGMRVQLPHVMGSARLQ--QLAGYVIVRH 182
Query: 188 DFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWR 247
+++D V + + G GLCGN + +P +D V +G L + + SW+
Sbjct: 183 QSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ 242
Query: 248 --APGWDP------LCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVP 299
AP P L C P + EQ E L P PF CHA+V
Sbjct: 243 EQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEAL-----LRP----PFDACHAYVS 293
Query: 300 PESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVVIEDWRAQV-GCEITCPENSH- 357
P F C D+C GD C+ALA Y AC AG ++ WR Q+ C + C E +
Sbjct: 294 PLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFT 353
Query: 358 YEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTY 417
Y C CPASC P + E CV+GC C G + CV C C +GT
Sbjct: 354 YNECIACCPASC---HPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE-CPCEFHGTL 409
Query: 418 HEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAW 477
+ GS D C+ C C G C+ A C AEC
Sbjct: 410 YPPGSVVKED--CNT-CTC--TSGKWECSTAVC--------------------PAECSVT 444
Query: 478 GDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTL 536
GD H+ T DG R+ F TC+Y+L+ + FTVT+ N G +Q + +SV++
Sbjct: 445 GDIHFTTFDGRRYTFPATCQYILA-----KSRSSGTFTVTLQNAPCGLNQDGACVQSVSV 499
Query: 537 QIY---NHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDG 593
++ +TL+ L D + P+ D+ LS + V T G+ + +D
Sbjct: 500 ILHQDPRRQVTLTQAGD-VLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDR 558
Query: 594 DSF-VRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQGCGE 644
+ + L+V + GLCG +N + DD + G P W+ A C
Sbjct: 559 EGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA--CSP 616
Query: 645 CVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGH 704
VS PC Q + AC V+ T APC + P YF+ C DAC+ G
Sbjct: 617 LVSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDACRC-GQ 673
Query: 705 PGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEG 764
P LC +A Y C+ G + R C L C A Y C C +C L++PE
Sbjct: 674 P-CLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEA 732
Query: 765 C---------ESACREGCVC--DAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPG--- 810
C C EGC C D D CVP QC C G YP G+ P
Sbjct: 733 CGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGH 792
Query: 811 -------PECERRCECG--PGGHV-----------------TCQE--------------- 829
C+ R P G V TC++
Sbjct: 793 CHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLS 852
Query: 830 -----------GAACGPHEECRL----------EDGVQACHATGCGR------------- 855
G AC EEC + + CH C R
Sbjct: 853 GCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPCAST 912
Query: 856 CLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEK---NAAGDLQRLLV 912
C A G HY T DG +D G+C L + D FS+++E ++G + R
Sbjct: 913 CTAYGDRHYRTFDGLPFDFVGACKVHLVK----STSDVSFSVIVENVNCYSSGMICR--- 965
Query: 913 TVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGR-------NMVLQTTKGLRLLFD 965
+ +S+ G + V + P + E +V + + LL+D
Sbjct: 966 ----KFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWD 1021
Query: 966 GDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCG 1025
+ + ++G+L GLCGNF+ ++ P ++ + FG++W ++ C
Sbjct: 1022 QRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSW----AAVECP 1077
Query: 1026 EGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDL--CAQ 1083
+ P+ +C+ + + C L + F C V+ + ++ C+ D C+Q
Sbjct: 1078 DTLDPR--DMCVLNPLREPFAKKECSILLSE--VFEICHPVVDVTWFYSNCLTDTCGCSQ 1133
Query: 1084 KGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHC 1121
GD C S++AY C GVAV WRT CP C
Sbjct: 1134 GGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1170
Score = 254 bits (649), Expect = 4e-67
Identities = 233/821 (28%), Positives = 317/821 (38%), Gaps = 90/821 (10%)
Query: 440 GGSLVCTPASCGLGEVCGLLPSGQ--HGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCE 497
GG V PA C P Q + P + C+AWG H T DG + G
Sbjct: 44 GGECV-HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGS 102
Query: 498 YLLSAPCHGPPLGAENFTVTVANEHR-GSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD 556
Y L H P ++F++ V N+ + GS + +R+V+L +++
Sbjct: 103 YTLVGR-HEPE--GQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQ---EIHLAKEVTHG 156
Query: 557 GVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNY 616
G+ V LP + S L+G V+V S +LA+DG S V +++ GLCGN
Sbjct: 157 GMRVQLPHVMGSARLQQLAGY-VIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNN 215
Query: 617 NQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCT------PEQQESFGGPDACGV 670
N DP DDL GK V E P P T P Q++ G GV
Sbjct: 216 NADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQ--GV 273
Query: 671 ISATDGPLAP----CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQL 726
+ L P CH V P + C D CQ G C A+A Y AC AG L
Sbjct: 274 YEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 333
Query: 727 GEWRRP-DFCPLQCPAHSH-YELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGD 784
WR C + C + Y C CP SC ++ E AC +GC C G +
Sbjct: 334 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDG 393
Query: 785 TCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDG 844
CV +C C G YP PG + C C G
Sbjct: 394 GCVAPAECPCEFHGTLYP------PGSVVKEDCNT-------------------CTCTSG 428
Query: 845 VQACHATGC-GRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNA 903
C C C G IH+ T DGR Y +C Y+LA+ F++ L+
Sbjct: 429 KWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAK----SRSSGTFTVTLQNAP 484
Query: 904 AG---------DLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVL 954
G + +L + V+L Q V + + +P ++ L
Sbjct: 485 CGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFL 544
Query: 955 Q--TTKGLRLLFDGDA-HLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETF 1011
+ T G+R+L+D + L + + + GLCG FNGN DDF+ P G S+ + F
Sbjct: 545 RVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLF 604
Query: 1012 GAAWRVPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSE 1071
G +W+ + G C V L + A Y S +AC L FA C A LSP
Sbjct: 605 GNSWKTLSACSPLVSGSPLDPCDVHL--QAASY-SVQACSVLTGEM--FAPCSAFLSPVP 659
Query: 1072 YFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICT 1131
YF QC D C + + LC +LA Y C+ G+ V C L C A YS C
Sbjct: 660 YFEQCRRDAC--RCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCV 717
Query: 1132 RTCQGSCAALSGLTGC---------TTRCFEGCEC-DDRFLLSQG-VCIPVQDCGCTHNG 1180
C +C L+ C C EGC C D +L +Q +C+P C C G
Sbjct: 718 APCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQG 777
Query: 1181 RYLPVNSSLLTSDCSERCSCSS---SSGLTCQAAGCPPGRV 1218
P S + S C C S AA CP G+V
Sbjct: 778 VDYPPGDSDIPS--LGHCHCKDGVMSCDSRAPAAACPAGQV 816
Score = 161 bits (407), Expect = 5e-39
Identities = 154/588 (26%), Positives = 227/588 (38%), Gaps = 47/588 (7%)
Query: 816 RCECGPGGHVTCQEGAACGPHE--ECRLEDGV----QACHATGCGR---CLANGGIHYIT 866
R +C P +C G C +CR + Q + G R C A G H T
Sbjct: 30 RAKCAPSYLFSCFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVET 89
Query: 867 LDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRL-------LVTVAGQVV 919
DG Y L G SY L V +P + FSI + + L V Q +
Sbjct: 90 FDGLYYYLSGKGSYTL--VGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEI 147
Query: 920 SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFR 979
LA+ +VT G V LP +G R+ ++++ L +DG + + + +
Sbjct: 148 HLAK--EVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELL 205
Query: 980 GRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEGCGPQGCPVCLAE 1039
G GLCGN N + DD V +G V F +W+ ++ G P CL +
Sbjct: 206 GWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQ 265
Query: 1040 ETAPYES-NEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYT 1098
+ E C L P PF C A +SP + C DLC GD A CR+LA Y
Sbjct: 266 NPGTMQGVYEQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYA 323
Query: 1099 AACQAAGVAVKPWRTD-SFCPLHCPAHSH-YSICTRTCQGSCAALSGLTGCTTRCFEGCE 1156
AC AG ++ WRT C +HC + Y+ C C SC + C +GC
Sbjct: 324 RACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCY 383
Query: 1157 CDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPG 1216
C + + G C+ +C C +G P S++ DC+ C+C+S C A CP
Sbjct: 384 CPNGLIFEDGGCVAPAECPCEFHGTLYP-PGSVVKEDCN-TCTCTSGK-WECSTAVCP-- 438
Query: 1217 RVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYR 1276
AE C ++ + TTFDG R + Y L+ T+
Sbjct: 439 ------AE----------CSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQN 482
Query: 1277 VVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDG 1336
+ ++V + VTLT V + +P + + R
Sbjct: 483 APCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSV 542
Query: 1337 SLLVRQKAGVQVWLGANG-KVAVIVSNDHAGKLCGACGNFDGDQTNDW 1383
L VR GV+V G ++ + V G CG F+G+ +D+
Sbjct: 543 FLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDF 590
Score = 94.0 bits (232), Expect = 9e-19
Identities = 118/502 (23%), Positives = 190/502 (37%), Gaps = 87/502 (17%)
Query: 755 SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLH----DGRYYPLGEVFYPG 810
S P+LS EG A + + TCVP+ + C+ +G+ + + +
Sbjct: 1953 SAPALSIVEGLAEALATTTEAN-----TSTTCVPIAEQDCVRHICLEGQLIRVNQSQHC- 2006
Query: 811 PECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGR 870
P+ CG G G C P EC AC RC + ++T DG
Sbjct: 2007 PQGAAPPRCGILGLAVRVGGDRCCPLWEC-------AC------RCSIFPDLSFVTFDGS 2053
Query: 871 VYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRL-----------LVTVAGQVV 919
L Y+L+Q DE ++ + + +L L + +A QV
Sbjct: 2054 HVALFKEAIYILSQ-----SPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVT 2108
Query: 920 SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLM---SIPS 976
++VTVD + V PV+ R+ G ++ T +++ + + L++ S S
Sbjct: 2109 IDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTS 2168
Query: 977 PFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVET---FGAAWRVPGSSKGCGE------G 1027
+G GLCG +G+ ++D L +GS E F +W+VP S G+
Sbjct: 2169 KAQGH--GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDS 2226
Query: 1028 CGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDK 1087
C C CL + AC + P+ + C+ + ++Y +Q
Sbjct: 2227 CATTDCSPCL--RMVSNRTFSACHRFVPPE---SFCELWIRDTKYVQQP----------- 2270
Query: 1088 AFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTG- 1146
C +L Y A C V ++ WR +CP C + S Y C C+ G+ G
Sbjct: 2271 ---CVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGP 2326
Query: 1147 -----CTTRCFEGCECDDRFLLSQ---GVCIPVQDCGCTHN---GRYLPVNSSLLTSDCS 1195
C EGC C + +L + +CIP C CT + R L + S C
Sbjct: 2327 LDPEHCQV-LGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCC 2385
Query: 1196 ERCSCSSSSGLTCQAAGCPPGR 1217
+ C + + GCP R
Sbjct: 2386 QH-QCQAPDTIVPVDLGCPSPR 2406
Score = 84.7 bits (208), Expect = 6e-16
Identities = 105/415 (25%), Positives = 157/415 (37%), Gaps = 79/415 (19%)
Query: 447 PASCGLGEVCGL-LPSGQHGCQPV--STAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAP 503
P CG + GL + G C P+ C + D +VT DG Y+LS
Sbjct: 2012 PPRCG---ILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS 2068
Query: 504 -----------CHGPPLGAEN---FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSAR- 548
C LG N F + + N VT+ +N +T+ +
Sbjct: 2069 PDEMLTVHVLDCKSANLGHLNWPPFCLVMLN------MTHLAHQVTIDRFNRKVTVDLQP 2122
Query: 549 -WPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRL----RVPA 603
WP + F+++ H ++ + T S + + + S + + +
Sbjct: 2123 VWPPVSRYG-------FRIEDTGHMYM------ILTPSDIQIQWLHSSGLMIVEASKTSK 2169
Query: 604 AYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECV-SKPCPSPCTPEQQESF 662
A LCG+C D A+DL G VGGA+ + S PS T Q F
Sbjct: 2170 AQGHGLCGICDG---DAANDLTLKDGSV----VGGAEDPAPFLDSWQVPSSLTSVGQTRF 2222
Query: 663 GGPDACGVISAT-------DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATY 715
PD+C + + + CH VPP + + + D VQ C A+ Y
Sbjct: 2223 R-PDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVY 2277
Query: 716 VAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSC--PVSCP----SLSAPEGCESAC 769
VA C + EWRR D+CP C + S Y+ C +C P +C PE C+
Sbjct: 2278 VAMCHKFHVCI-EWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQ-VL 2335
Query: 770 REGCVCDAGFVL---SGDTCVPVGQCGCLHD-GRYYPLGEVFYPGPE--CERRCE 818
EGCVC G +L C+P +C C G LGE + C+ +C+
Sbjct: 2336 GEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQ 2390
Score = 80.9 bits (198), Expect = 8e-15
Identities = 77/315 (24%), Positives = 117/315 (37%), Gaps = 43/315 (13%)
Query: 46 PCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTG 105
PCH C ++G L +TC +GD HY +FDG FDF G C L
Sbjct: 891 PCHTCVC-------QRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHL---- 939
Query: 106 CLGVSTQGLTPFTVTTKNENRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTAL 165
V + F+V +N N + + + +++ +G ++ + D+ G
Sbjct: 940 ---VKSTSDVSFSVIVENVNCYSSGMICRKFISI-NVGNSLIVFDDDSG--------NPS 987
Query: 166 PVSVADGRISVAQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDR 222
P S D + V + F + + +D V V + G + GLCGN D
Sbjct: 988 PESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDL 1047
Query: 223 NPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSC---PTCPEDRLEQYEGPGF 279
N+ P + +G SW A EC + C + L +
Sbjct: 1048 KTINEMRTPENLELTNPQEFGSSWAAV--------ECPDTLDPRDMCVLNPLREPFAKKE 1099
Query: 280 CGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDHDILCKALASYVAACQAAGV 337
C L F CH V F+ C+ D C GGD + C ++++Y C GV
Sbjct: 1100 CSILLSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGV 1156
Query: 338 VIEDWRAQVGCEITC 352
+ DWR C C
Sbjct: 1157 AV-DWRTPRLCPYDC 1170
Score = 64.3 bits (155), Expect = 8e-10
Identities = 112/432 (25%), Positives = 157/432 (36%), Gaps = 65/432 (15%)
Query: 67 CLPNYEATCW--LWGDPHYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLTPFTVTTKNE 124
C P +E C ++ D + +FDG Y+L+ + + LT + K+
Sbjct: 2029 CCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS-----PDEMLTVHVLDCKSA 2083
Query: 125 NRGN---PAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGAS 181
N G+ P V ++ + L ++I + KV V+ PVS RI
Sbjct: 2084 NLGHLNWPPFCLV-MLNMTHLAHQVTIDRFN-RKVTVDLQPVWPPVSRYGFRIEDTGHMY 2141
Query: 182 KALLVADFGLQVSYDWNWR-VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTL----- 235
L +D +Q + V+ + S G GLCG D + ND +G++
Sbjct: 2142 MILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLKDGSVVGGAE 2199
Query: 236 --APSIPIWG--GSWRAPGWDPLCWDECRGS-CPTCPEDRLEQYEGPGFCGPLAPGTGGP 290
AP + W S + G D C + C C L +
Sbjct: 2200 DPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPC----------------LRMVSNRT 2243
Query: 291 FTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVVIEDWRAQVGCEI 350
F+ CH VPPESF + + D C AL YVA C V IE WR C
Sbjct: 2244 FSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCIE-WRRSDYCPF 2298
Query: 351 TCPENSHYEVCGPPC--PASCPSP--APLTTPAVCEGPCVEGCQCDAGFVL---SADRCV 403
C +S Y+ C C P +C PL P C+ EGC C G +L + C+
Sbjct: 2299 LCSSDSTYQACVTACEPPKTCQDGILGPL-DPEHCQ-VLGEGCVCSEGTILHRRHSALCI 2356
Query: 404 PLNNGCGCWANGTYHEAGSEFW---ADGTCSQWCRCGP-----GGGSLVCTPASC-GLGE 454
P C C + A E W G C C+ G P SC GE
Sbjct: 2357 P-EAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGE 2415
Query: 455 VCGLLPSGQHGC 466
V LLP+ C
Sbjct: 2416 VALLLPTKDPCC 2427
Score = 32.7 bits (73), Expect = 2.5
Identities = 26/96 (27%), Positives = 33/96 (34%), Gaps = 17/96 (17%)
Query: 1121 CPAHSHYSICT-----------RTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCI 1169
CPA + C+ RTC+ LS C GC C L C
Sbjct: 811 CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLS--VSARGPCLSGCACPQGLLRHGDACF 868
Query: 1170 PVQDCGCTHNGR-YLPVNSSLLTSDCSERCSCSSSS 1204
++C CT G+ Y P + S C C C S
Sbjct: 869 LPEECPCTWKGKEYFP--GDQVMSPC-HTCVCQRGS 901
>gi|239749987 PREDICTED: otogelin isoform 1 [Homo sapiens]
Length = 2924
Score = 297 bits (761), Expect = 4e-80
Identities = 305/1178 (25%), Positives = 452/1178 (38%), Gaps = 205/1178 (17%)
Query: 69 PNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLTPFTVTTKNENR-G 127
P ++ C WG H +FDG + G +Y L +G F++ N+ + G
Sbjct: 145 PERDSICRAWGQHHVETFDGLYYYLSGKGSYTL-----VGRHEPEGQSFSIQVHNDPQCG 199
Query: 128 NPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVA 187
+ + R V++ +G IH + +V G+ LP + R+ Q A ++
Sbjct: 200 SSPYTCSRAVSLFFVGEQ-EIHLAK--EVTHGGMRVQLPHVMGSARLQ--QLAGYVIVRH 254
Query: 188 DFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWR 247
+++D V + + G GLCGN + +P +D V +G L + + SW+
Sbjct: 255 QSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ 314
Query: 248 --APGWDP------LCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVP 299
AP P L C P + EQ E L P PF CHA+V
Sbjct: 315 EQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEAL-----LRP----PFDACHAYVS 365
Query: 300 PESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVVIEDWRAQV-GCEITCPENSH- 357
P F C D+C GD C+ALA Y AC AG ++ WR Q+ C + C E +
Sbjct: 366 PLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFT 425
Query: 358 YEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTY 417
Y C CPASC P + E CV+GC C G + CV C C +GT
Sbjct: 426 YNECIACCPASC---HPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE-CPCEFHGTL 481
Query: 418 HEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAW 477
+ GS D C+ C C G C+ A C AEC
Sbjct: 482 YPPGSVVKED--CNT-CTC--TSGKWECSTAVC--------------------PAECSVT 516
Query: 478 GDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTL 536
GD H+ T DG R+ F TC+Y+L+ + FTVT+ N G +Q + +SV++
Sbjct: 517 GDIHFTTFDGRRYTFPATCQYILA-----KSRSSGTFTVTLQNAPCGLNQDGACVQSVSV 571
Query: 537 QIY---NHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDG 593
++ +TL+ L D + P+ D+ LS + V T G+ + +D
Sbjct: 572 ILHQDPRRQVTLTQAGD-VLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDR 630
Query: 594 DSF-VRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQGCGE 644
+ + L+V + GLCG +N + DD + G P W+ A C
Sbjct: 631 EGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA--CSP 688
Query: 645 CVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGH 704
VS PC Q + AC V+ T APC + P YF+ C DAC+ G
Sbjct: 689 LVSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDACRC-GQ 745
Query: 705 PGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEG 764
P LC +A Y C+ G + R C L C A Y C C +C L++PE
Sbjct: 746 P-CLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEA 804
Query: 765 C---------ESACREGCVC--DAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPG--- 810
C C EGC C D D CVP QC C G YP G+ P
Sbjct: 805 CGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGH 864
Query: 811 -------PECERRCECG--PGGHV-----------------TCQE--------------- 829
C+ R P G V TC++
Sbjct: 865 CHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLS 924
Query: 830 -----------GAACGPHEECRL----------EDGVQACHATGCGR------------- 855
G AC EEC + + CH C R
Sbjct: 925 GCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPCAST 984
Query: 856 CLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEK---NAAGDLQRLLV 912
C A G HY T DG +D G+C L + D FS+++E ++G + R
Sbjct: 985 CTAYGDRHYRTFDGLPFDFVGACKVHLVK----STSDVSFSVIVENVNCYSSGMICR--- 1037
Query: 913 TVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGR-------NMVLQTTKGLRLLFD 965
+ +S+ G + V + P + E +V + + LL+D
Sbjct: 1038 ----KFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWD 1093
Query: 966 GDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCG 1025
+ + ++G+L GLCGNF+ ++ P ++ + FG++W ++ C
Sbjct: 1094 QRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSW----AAVECP 1149
Query: 1026 EGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDL--CAQ 1083
+ P+ +C+ + + C L + F C V+ + ++ C+ D C+Q
Sbjct: 1150 DTLDPR--DMCVLNPLREPFAKKECSILLSE--VFEICHPVVDVTWFYSNCLTDTCGCSQ 1205
Query: 1084 KGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHC 1121
GD C S++AY C GVAV WRT CP C
Sbjct: 1206 GGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1242
Score = 254 bits (649), Expect = 4e-67
Identities = 233/821 (28%), Positives = 317/821 (38%), Gaps = 90/821 (10%)
Query: 440 GGSLVCTPASCGLGEVCGLLPSGQ--HGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCE 497
GG V PA C P Q + P + C+AWG H T DG + G
Sbjct: 116 GGECV-HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGS 174
Query: 498 YLLSAPCHGPPLGAENFTVTVANEHR-GSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD 556
Y L H P ++F++ V N+ + GS + +R+V+L +++
Sbjct: 175 YTLVGR-HEPE--GQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQ---EIHLAKEVTHG 228
Query: 557 GVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNY 616
G+ V LP + S L+G V+V S +LA+DG S V +++ GLCGN
Sbjct: 229 GMRVQLPHVMGSARLQQLAGY-VIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNN 287
Query: 617 NQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCT------PEQQESFGGPDACGV 670
N DP DDL GK V E P P T P Q++ G GV
Sbjct: 288 NADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQ--GV 345
Query: 671 ISATDGPLAP----CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQL 726
+ L P CH V P + C D CQ G C A+A Y AC AG L
Sbjct: 346 YEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 405
Query: 727 GEWRRP-DFCPLQCPAHSH-YELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGD 784
WR C + C + Y C CP SC ++ E AC +GC C G +
Sbjct: 406 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDG 465
Query: 785 TCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDG 844
CV +C C G YP PG + C C G
Sbjct: 466 GCVAPAECPCEFHGTLYP------PGSVVKEDCNT-------------------CTCTSG 500
Query: 845 VQACHATGC-GRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNA 903
C C C G IH+ T DGR Y +C Y+LA+ F++ L+
Sbjct: 501 KWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAK----SRSSGTFTVTLQNAP 556
Query: 904 AG---------DLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVL 954
G + +L + V+L Q V + + +P ++ L
Sbjct: 557 CGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFL 616
Query: 955 Q--TTKGLRLLFDGDA-HLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETF 1011
+ T G+R+L+D + L + + + GLCG FNGN DDF+ P G S+ + F
Sbjct: 617 RVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLF 676
Query: 1012 GAAWRVPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSE 1071
G +W+ + G C V L + A Y S +AC L FA C A LSP
Sbjct: 677 GNSWKTLSACSPLVSGSPLDPCDVHL--QAASY-SVQACSVLTGEM--FAPCSAFLSPVP 731
Query: 1072 YFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICT 1131
YF QC D C + + LC +LA Y C+ G+ V C L C A YS C
Sbjct: 732 YFEQCRRDAC--RCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCV 789
Query: 1132 RTCQGSCAALSGLTGC---------TTRCFEGCEC-DDRFLLSQG-VCIPVQDCGCTHNG 1180
C +C L+ C C EGC C D +L +Q +C+P C C G
Sbjct: 790 APCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQG 849
Query: 1181 RYLPVNSSLLTSDCSERCSCSS---SSGLTCQAAGCPPGRV 1218
P S + S C C S AA CP G+V
Sbjct: 850 VDYPPGDSDIPS--LGHCHCKDGVMSCDSRAPAAACPAGQV 888
Score = 161 bits (407), Expect = 5e-39
Identities = 154/588 (26%), Positives = 227/588 (38%), Gaps = 47/588 (7%)
Query: 816 RCECGPGGHVTCQEGAACGPHE--ECRLEDGV----QACHATGCGR---CLANGGIHYIT 866
R +C P +C G C +CR + Q + G R C A G H T
Sbjct: 102 RAKCAPSYLFSCFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVET 161
Query: 867 LDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRL-------LVTVAGQVV 919
DG Y L G SY L V +P + FSI + + L V Q +
Sbjct: 162 FDGLYYYLSGKGSYTL--VGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEI 219
Query: 920 SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFR 979
LA+ +VT G V LP +G R+ ++++ L +DG + + + +
Sbjct: 220 HLAK--EVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELL 277
Query: 980 GRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEGCGPQGCPVCLAE 1039
G GLCGN N + DD V +G V F +W+ ++ G P CL +
Sbjct: 278 GWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQ 337
Query: 1040 ETAPYES-NEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYT 1098
+ E C L P PF C A +SP + C DLC GD A CR+LA Y
Sbjct: 338 NPGTMQGVYEQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYA 395
Query: 1099 AACQAAGVAVKPWRTD-SFCPLHCPAHSH-YSICTRTCQGSCAALSGLTGCTTRCFEGCE 1156
AC AG ++ WRT C +HC + Y+ C C SC + C +GC
Sbjct: 396 RACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCY 455
Query: 1157 CDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPG 1216
C + + G C+ +C C +G P S++ DC+ C+C+S C A CP
Sbjct: 456 CPNGLIFEDGGCVAPAECPCEFHGTLYP-PGSVVKEDCN-TCTCTSGK-WECSTAVCP-- 510
Query: 1217 RVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYR 1276
AE C ++ + TTFDG R + Y L+ T+
Sbjct: 511 ------AE----------CSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQN 554
Query: 1277 VVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDG 1336
+ ++V + VTLT V + +P + + R
Sbjct: 555 APCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSV 614
Query: 1337 SLLVRQKAGVQVWLGANG-KVAVIVSNDHAGKLCGACGNFDGDQTNDW 1383
L VR GV+V G ++ + V G CG F+G+ +D+
Sbjct: 615 FLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDF 662
Score = 94.0 bits (232), Expect = 9e-19
Identities = 118/502 (23%), Positives = 190/502 (37%), Gaps = 87/502 (17%)
Query: 755 SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLH----DGRYYPLGEVFYPG 810
S P+LS EG A + + TCVP+ + C+ +G+ + + +
Sbjct: 2025 SAPALSIVEGLAEALATTTEAN-----TSTTCVPIAEQDCVRHICLEGQLIRVNQSQHC- 2078
Query: 811 PECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGR 870
P+ CG G G C P EC AC RC + ++T DG
Sbjct: 2079 PQGAAPPRCGILGLAVRVGGDRCCPLWEC-------AC------RCSIFPDLSFVTFDGS 2125
Query: 871 VYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRL-----------LVTVAGQVV 919
L Y+L+Q DE ++ + + +L L + +A QV
Sbjct: 2126 HVALFKEAIYILSQ-----SPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVT 2180
Query: 920 SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLM---SIPS 976
++VTVD + V PV+ R+ G ++ T +++ + + L++ S S
Sbjct: 2181 IDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTS 2240
Query: 977 PFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVET---FGAAWRVPGSSKGCGE------G 1027
+G GLCG +G+ ++D L +GS E F +W+VP S G+
Sbjct: 2241 KAQGH--GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDS 2298
Query: 1028 CGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDK 1087
C C CL + AC + P+ + C+ + ++Y +Q
Sbjct: 2299 CATTDCSPCL--RMVSNRTFSACHRFVPPE---SFCELWIRDTKYVQQP----------- 2342
Query: 1088 AFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTG- 1146
C +L Y A C V ++ WR +CP C + S Y C C+ G+ G
Sbjct: 2343 ---CVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGP 2398
Query: 1147 -----CTTRCFEGCECDDRFLLSQ---GVCIPVQDCGCTHN---GRYLPVNSSLLTSDCS 1195
C EGC C + +L + +CIP C CT + R L + S C
Sbjct: 2399 LDPEHCQV-LGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCC 2457
Query: 1196 ERCSCSSSSGLTCQAAGCPPGR 1217
+ C + + GCP R
Sbjct: 2458 QH-QCQAPDTIVPVDLGCPSPR 2478
Score = 84.7 bits (208), Expect = 6e-16
Identities = 105/415 (25%), Positives = 157/415 (37%), Gaps = 79/415 (19%)
Query: 447 PASCGLGEVCGL-LPSGQHGCQPV--STAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAP 503
P CG + GL + G C P+ C + D +VT DG Y+LS
Sbjct: 2084 PPRCG---ILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS 2140
Query: 504 -----------CHGPPLGAEN---FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSAR- 548
C LG N F + + N VT+ +N +T+ +
Sbjct: 2141 PDEMLTVHVLDCKSANLGHLNWPPFCLVMLN------MTHLAHQVTIDRFNRKVTVDLQP 2194
Query: 549 -WPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRL----RVPA 603
WP + F+++ H ++ + T S + + + S + + +
Sbjct: 2195 VWPPVSRYG-------FRIEDTGHMYM------ILTPSDIQIQWLHSSGLMIVEASKTSK 2241
Query: 604 AYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECV-SKPCPSPCTPEQQESF 662
A LCG+C D A+DL G VGGA+ + S PS T Q F
Sbjct: 2242 AQGHGLCGICDG---DAANDLTLKDGSV----VGGAEDPAPFLDSWQVPSSLTSVGQTRF 2294
Query: 663 GGPDACGVISAT-------DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATY 715
PD+C + + + CH VPP + + + D VQ C A+ Y
Sbjct: 2295 R-PDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVY 2349
Query: 716 VAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSC--PVSCP----SLSAPEGCESAC 769
VA C + EWRR D+CP C + S Y+ C +C P +C PE C+
Sbjct: 2350 VAMCHKFHVCI-EWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQ-VL 2407
Query: 770 REGCVCDAGFVL---SGDTCVPVGQCGCLHD-GRYYPLGEVFYPGPE--CERRCE 818
EGCVC G +L C+P +C C G LGE + C+ +C+
Sbjct: 2408 GEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQ 2462
Score = 80.9 bits (198), Expect = 8e-15
Identities = 77/315 (24%), Positives = 117/315 (37%), Gaps = 43/315 (13%)
Query: 46 PCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTG 105
PCH C ++G L +TC +GD HY +FDG FDF G C L
Sbjct: 963 PCHTCVC-------QRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHL---- 1011
Query: 106 CLGVSTQGLTPFTVTTKNENRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTAL 165
V + F+V +N N + + + +++ +G ++ + D+ G
Sbjct: 1012 ---VKSTSDVSFSVIVENVNCYSSGMICRKFISI-NVGNSLIVFDDDSG--------NPS 1059
Query: 166 PVSVADGRISVAQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDR 222
P S D + V + F + + +D V V + G + GLCGN D
Sbjct: 1060 PESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDL 1119
Query: 223 NPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSC---PTCPEDRLEQYEGPGF 279
N+ P + +G SW A EC + C + L +
Sbjct: 1120 KTINEMRTPENLELTNPQEFGSSWAAV--------ECPDTLDPRDMCVLNPLREPFAKKE 1171
Query: 280 CGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDHDILCKALASYVAACQAAGV 337
C L F CH V F+ C+ D C GGD + C ++++Y C GV
Sbjct: 1172 CSILLSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGV 1228
Query: 338 VIEDWRAQVGCEITC 352
+ DWR C C
Sbjct: 1229 AV-DWRTPRLCPYDC 1242
Score = 64.3 bits (155), Expect = 8e-10
Identities = 112/432 (25%), Positives = 157/432 (36%), Gaps = 65/432 (15%)
Query: 67 CLPNYEATCW--LWGDPHYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLTPFTVTTKNE 124
C P +E C ++ D + +FDG Y+L+ + + LT + K+
Sbjct: 2101 CCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS-----PDEMLTVHVLDCKSA 2155
Query: 125 NRGN---PAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGAS 181
N G+ P V ++ + L ++I + KV V+ PVS RI
Sbjct: 2156 NLGHLNWPPFCLV-MLNMTHLAHQVTIDRFN-RKVTVDLQPVWPPVSRYGFRIEDTGHMY 2213
Query: 182 KALLVADFGLQVSYDWNWR-VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTL----- 235
L +D +Q + V+ + S G GLCG D + ND +G++
Sbjct: 2214 MILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLKDGSVVGGAE 2271
Query: 236 --APSIPIWG--GSWRAPGWDPLCWDECRGS-CPTCPEDRLEQYEGPGFCGPLAPGTGGP 290
AP + W S + G D C + C C L +
Sbjct: 2272 DPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPC----------------LRMVSNRT 2315
Query: 291 FTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVVIEDWRAQVGCEI 350
F+ CH VPPESF + + D C AL YVA C V IE WR C
Sbjct: 2316 FSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCIE-WRRSDYCPF 2370
Query: 351 TCPENSHYEVCGPPC--PASCPSP--APLTTPAVCEGPCVEGCQCDAGFVL---SADRCV 403
C +S Y+ C C P +C PL P C+ EGC C G +L + C+
Sbjct: 2371 LCSSDSTYQACVTACEPPKTCQDGILGPL-DPEHCQ-VLGEGCVCSEGTILHRRHSALCI 2428
Query: 404 PLNNGCGCWANGTYHEAGSEFW---ADGTCSQWCRCGP-----GGGSLVCTPASC-GLGE 454
P C C + A E W G C C+ G P SC GE
Sbjct: 2429 P-EAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGE 2487
Query: 455 VCGLLPSGQHGC 466
V LLP+ C
Sbjct: 2488 VALLLPTKDPCC 2499
Score = 32.7 bits (73), Expect = 2.5
Identities = 26/96 (27%), Positives = 33/96 (34%), Gaps = 17/96 (17%)
Query: 1121 CPAHSHYSICT-----------RTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCI 1169
CPA + C+ RTC+ LS C GC C L C
Sbjct: 883 CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLS--VSARGPCLSGCACPQGLLRHGDACF 940
Query: 1170 PVQDCGCTHNGR-YLPVNSSLLTSDCSERCSCSSSS 1204
++C CT G+ Y P + S C C C S
Sbjct: 941 LPEECPCTWKGKEYFP--GDQVMSPC-HTCVCQRGS 973
>gi|239744300 PREDICTED: otogelin isoform 2 [Homo sapiens]
Length = 2852
Score = 297 bits (761), Expect = 4e-80
Identities = 305/1178 (25%), Positives = 452/1178 (38%), Gaps = 205/1178 (17%)
Query: 69 PNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLTPFTVTTKNENR-G 127
P ++ C WG H +FDG + G +Y L +G F++ N+ + G
Sbjct: 73 PERDSICRAWGQHHVETFDGLYYYLSGKGSYTL-----VGRHEPEGQSFSIQVHNDPQCG 127
Query: 128 NPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVA 187
+ + R V++ +G IH + +V G+ LP + R+ Q A ++
Sbjct: 128 SSPYTCSRAVSLFFVGEQ-EIHLAK--EVTHGGMRVQLPHVMGSARLQ--QLAGYVIVRH 182
Query: 188 DFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWR 247
+++D V + + G GLCGN + +P +D V +G L + + SW+
Sbjct: 183 QSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ 242
Query: 248 --APGWDP------LCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVP 299
AP P L C P + EQ E L P PF CHA+V
Sbjct: 243 EQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEAL-----LRP----PFDACHAYVS 293
Query: 300 PESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVVIEDWRAQV-GCEITCPENSH- 357
P F C D+C GD C+ALA Y AC AG ++ WR Q+ C + C E +
Sbjct: 294 PLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFT 353
Query: 358 YEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTY 417
Y C CPASC P + E CV+GC C G + CV C C +GT
Sbjct: 354 YNECIACCPASC---HPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE-CPCEFHGTL 409
Query: 418 HEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAW 477
+ GS D C+ C C G C+ A C AEC
Sbjct: 410 YPPGSVVKED--CNT-CTC--TSGKWECSTAVC--------------------PAECSVT 444
Query: 478 GDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTL 536
GD H+ T DG R+ F TC+Y+L+ + FTVT+ N G +Q + +SV++
Sbjct: 445 GDIHFTTFDGRRYTFPATCQYILA-----KSRSSGTFTVTLQNAPCGLNQDGACVQSVSV 499
Query: 537 QIY---NHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDG 593
++ +TL+ L D + P+ D+ LS + V T G+ + +D
Sbjct: 500 ILHQDPRRQVTLTQAGD-VLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDR 558
Query: 594 DSF-VRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQGCGE 644
+ + L+V + GLCG +N + DD + G P W+ A C
Sbjct: 559 EGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA--CSP 616
Query: 645 CVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGH 704
VS PC Q + AC V+ T APC + P YF+ C DAC+ G
Sbjct: 617 LVSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDACRC-GQ 673
Query: 705 PGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEG 764
P LC +A Y C+ G + R C L C A Y C C +C L++PE
Sbjct: 674 P-CLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEA 732
Query: 765 C---------ESACREGCVC--DAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPG--- 810
C C EGC C D D CVP QC C G YP G+ P
Sbjct: 733 CGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGH 792
Query: 811 -------PECERRCECG--PGGHV-----------------TCQE--------------- 829
C+ R P G V TC++
Sbjct: 793 CHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLS 852
Query: 830 -----------GAACGPHEECRL----------EDGVQACHATGCGR------------- 855
G AC EEC + + CH C R
Sbjct: 853 GCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPCAST 912
Query: 856 CLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEK---NAAGDLQRLLV 912
C A G HY T DG +D G+C L + D FS+++E ++G + R
Sbjct: 913 CTAYGDRHYRTFDGLPFDFVGACKVHLVK----STSDVSFSVIVENVNCYSSGMICR--- 965
Query: 913 TVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGR-------NMVLQTTKGLRLLFD 965
+ +S+ G + V + P + E +V + + LL+D
Sbjct: 966 ----KFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWD 1021
Query: 966 GDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCG 1025
+ + ++G+L GLCGNF+ ++ P ++ + FG++W ++ C
Sbjct: 1022 QRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSW----AAVECP 1077
Query: 1026 EGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDL--CAQ 1083
+ P+ +C+ + + C L + F C V+ + ++ C+ D C+Q
Sbjct: 1078 DTLDPR--DMCVLNPLREPFAKKECSILLSE--VFEICHPVVDVTWFYSNCLTDTCGCSQ 1133
Query: 1084 KGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHC 1121
GD C S++AY C GVAV WRT CP C
Sbjct: 1134 GGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1170
Score = 254 bits (649), Expect = 4e-67
Identities = 233/821 (28%), Positives = 317/821 (38%), Gaps = 90/821 (10%)
Query: 440 GGSLVCTPASCGLGEVCGLLPSGQ--HGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCE 497
GG V PA C P Q + P + C+AWG H T DG + G
Sbjct: 44 GGECV-HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGS 102
Query: 498 YLLSAPCHGPPLGAENFTVTVANEHR-GSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD 556
Y L H P ++F++ V N+ + GS + +R+V+L +++
Sbjct: 103 YTLVGR-HEPE--GQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQ---EIHLAKEVTHG 156
Query: 557 GVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNY 616
G+ V LP + S L+G V+V S +LA+DG S V +++ GLCGN
Sbjct: 157 GMRVQLPHVMGSARLQQLAGY-VIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNN 215
Query: 617 NQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCT------PEQQESFGGPDACGV 670
N DP DDL GK V E P P T P Q++ G GV
Sbjct: 216 NADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQ--GV 273
Query: 671 ISATDGPLAP----CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQL 726
+ L P CH V P + C D CQ G C A+A Y AC AG L
Sbjct: 274 YEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 333
Query: 727 GEWRRP-DFCPLQCPAHSH-YELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGD 784
WR C + C + Y C CP SC ++ E AC +GC C G +
Sbjct: 334 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDG 393
Query: 785 TCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDG 844
CV +C C G YP PG + C C G
Sbjct: 394 GCVAPAECPCEFHGTLYP------PGSVVKEDCNT-------------------CTCTSG 428
Query: 845 VQACHATGC-GRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNA 903
C C C G IH+ T DGR Y +C Y+LA+ F++ L+
Sbjct: 429 KWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAK----SRSSGTFTVTLQNAP 484
Query: 904 AG---------DLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVL 954
G + +L + V+L Q V + + +P ++ L
Sbjct: 485 CGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFL 544
Query: 955 Q--TTKGLRLLFDGDA-HLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETF 1011
+ T G+R+L+D + L + + + GLCG FNGN DDF+ P G S+ + F
Sbjct: 545 RVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLF 604
Query: 1012 GAAWRVPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSE 1071
G +W+ + G C V L + A Y S +AC L FA C A LSP
Sbjct: 605 GNSWKTLSACSPLVSGSPLDPCDVHL--QAASY-SVQACSVLTGEM--FAPCSAFLSPVP 659
Query: 1072 YFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICT 1131
YF QC D C + + LC +LA Y C+ G+ V C L C A YS C
Sbjct: 660 YFEQCRRDAC--RCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCV 717
Query: 1132 RTCQGSCAALSGLTGC---------TTRCFEGCEC-DDRFLLSQG-VCIPVQDCGCTHNG 1180
C +C L+ C C EGC C D +L +Q +C+P C C G
Sbjct: 718 APCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQG 777
Query: 1181 RYLPVNSSLLTSDCSERCSCSS---SSGLTCQAAGCPPGRV 1218
P S + S C C S AA CP G+V
Sbjct: 778 VDYPPGDSDIPS--LGHCHCKDGVMSCDSRAPAAACPAGQV 816
Score = 161 bits (407), Expect = 5e-39
Identities = 154/588 (26%), Positives = 227/588 (38%), Gaps = 47/588 (7%)
Query: 816 RCECGPGGHVTCQEGAACGPHE--ECRLEDGV----QACHATGCGR---CLANGGIHYIT 866
R +C P +C G C +CR + Q + G R C A G H T
Sbjct: 30 RAKCAPSYLFSCFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVET 89
Query: 867 LDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRL-------LVTVAGQVV 919
DG Y L G SY L V +P + FSI + + L V Q +
Sbjct: 90 FDGLYYYLSGKGSYTL--VGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEI 147
Query: 920 SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFR 979
LA+ +VT G V LP +G R+ ++++ L +DG + + + +
Sbjct: 148 HLAK--EVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELL 205
Query: 980 GRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEGCGPQGCPVCLAE 1039
G GLCGN N + DD V +G V F +W+ ++ G P CL +
Sbjct: 206 GWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQ 265
Query: 1040 ETAPYES-NEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYT 1098
+ E C L P PF C A +SP + C DLC GD A CR+LA Y
Sbjct: 266 NPGTMQGVYEQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYA 323
Query: 1099 AACQAAGVAVKPWRTD-SFCPLHCPAHSH-YSICTRTCQGSCAALSGLTGCTTRCFEGCE 1156
AC AG ++ WRT C +HC + Y+ C C SC + C +GC
Sbjct: 324 RACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCY 383
Query: 1157 CDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPG 1216
C + + G C+ +C C +G P S++ DC+ C+C+S C A CP
Sbjct: 384 CPNGLIFEDGGCVAPAECPCEFHGTLYP-PGSVVKEDCN-TCTCTSGK-WECSTAVCP-- 438
Query: 1217 RVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYR 1276
AE C ++ + TTFDG R + Y L+ T+
Sbjct: 439 ------AE----------CSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQN 482
Query: 1277 VVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDG 1336
+ ++V + VTLT V + +P + + R
Sbjct: 483 APCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSV 542
Query: 1337 SLLVRQKAGVQVWLGANG-KVAVIVSNDHAGKLCGACGNFDGDQTNDW 1383
L VR GV+V G ++ + V G CG F+G+ +D+
Sbjct: 543 FLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDF 590
Score = 94.0 bits (232), Expect = 9e-19
Identities = 118/502 (23%), Positives = 190/502 (37%), Gaps = 87/502 (17%)
Query: 755 SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLH----DGRYYPLGEVFYPG 810
S P+LS EG A + + TCVP+ + C+ +G+ + + +
Sbjct: 1953 SAPALSIVEGLAEALATTTEAN-----TSTTCVPIAEQDCVRHICLEGQLIRVNQSQHC- 2006
Query: 811 PECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGR 870
P+ CG G G C P EC AC RC + ++T DG
Sbjct: 2007 PQGAAPPRCGILGLAVRVGGDRCCPLWEC-------AC------RCSIFPDLSFVTFDGS 2053
Query: 871 VYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRL-----------LVTVAGQVV 919
L Y+L+Q DE ++ + + +L L + +A QV
Sbjct: 2054 HVALFKEAIYILSQ-----SPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVT 2108
Query: 920 SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLM---SIPS 976
++VTVD + V PV+ R+ G ++ T +++ + + L++ S S
Sbjct: 2109 IDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTS 2168
Query: 977 PFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVET---FGAAWRVPGSSKGCGE------G 1027
+G GLCG +G+ ++D L +GS E F +W+VP S G+
Sbjct: 2169 KAQGH--GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDS 2226
Query: 1028 CGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDK 1087
C C CL + AC + P+ + C+ + ++Y +Q
Sbjct: 2227 CATTDCSPCL--RMVSNRTFSACHRFVPPE---SFCELWIRDTKYVQQP----------- 2270
Query: 1088 AFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTG- 1146
C +L Y A C V ++ WR +CP C + S Y C C+ G+ G
Sbjct: 2271 ---CVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGP 2326
Query: 1147 -----CTTRCFEGCECDDRFLLSQ---GVCIPVQDCGCTHN---GRYLPVNSSLLTSDCS 1195
C EGC C + +L + +CIP C CT + R L + S C
Sbjct: 2327 LDPEHCQV-LGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCC 2385
Query: 1196 ERCSCSSSSGLTCQAAGCPPGR 1217
+ C + + GCP R
Sbjct: 2386 QH-QCQAPDTIVPVDLGCPSPR 2406
Score = 84.7 bits (208), Expect = 6e-16
Identities = 105/415 (25%), Positives = 157/415 (37%), Gaps = 79/415 (19%)
Query: 447 PASCGLGEVCGL-LPSGQHGCQPV--STAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAP 503
P CG + GL + G C P+ C + D +VT DG Y+LS
Sbjct: 2012 PPRCG---ILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS 2068
Query: 504 -----------CHGPPLGAEN---FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSAR- 548
C LG N F + + N VT+ +N +T+ +
Sbjct: 2069 PDEMLTVHVLDCKSANLGHLNWPPFCLVMLN------MTHLAHQVTIDRFNRKVTVDLQP 2122
Query: 549 -WPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRL----RVPA 603
WP + F+++ H ++ + T S + + + S + + +
Sbjct: 2123 VWPPVSRYG-------FRIEDTGHMYM------ILTPSDIQIQWLHSSGLMIVEASKTSK 2169
Query: 604 AYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECV-SKPCPSPCTPEQQESF 662
A LCG+C D A+DL G VGGA+ + S PS T Q F
Sbjct: 2170 AQGHGLCGICDG---DAANDLTLKDGSV----VGGAEDPAPFLDSWQVPSSLTSVGQTRF 2222
Query: 663 GGPDACGVISAT-------DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATY 715
PD+C + + + CH VPP + + + D VQ C A+ Y
Sbjct: 2223 R-PDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVY 2277
Query: 716 VAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSC--PVSCP----SLSAPEGCESAC 769
VA C + EWRR D+CP C + S Y+ C +C P +C PE C+
Sbjct: 2278 VAMCHKFHVCI-EWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQ-VL 2335
Query: 770 REGCVCDAGFVL---SGDTCVPVGQCGCLHD-GRYYPLGEVFYPGPE--CERRCE 818
EGCVC G +L C+P +C C G LGE + C+ +C+
Sbjct: 2336 GEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQ 2390
Score = 80.9 bits (198), Expect = 8e-15
Identities = 77/315 (24%), Positives = 117/315 (37%), Gaps = 43/315 (13%)
Query: 46 PCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTG 105
PCH C ++G L +TC +GD HY +FDG FDF G C L
Sbjct: 891 PCHTCVC-------QRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHL---- 939
Query: 106 CLGVSTQGLTPFTVTTKNENRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTAL 165
V + F+V +N N + + + +++ +G ++ + D+ G
Sbjct: 940 ---VKSTSDVSFSVIVENVNCYSSGMICRKFISI-NVGNSLIVFDDDSG--------NPS 987
Query: 166 PVSVADGRISVAQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDR 222
P S D + V + F + + +D V V + G + GLCGN D
Sbjct: 988 PESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDL 1047
Query: 223 NPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSC---PTCPEDRLEQYEGPGF 279
N+ P + +G SW A EC + C + L +
Sbjct: 1048 KTINEMRTPENLELTNPQEFGSSWAAV--------ECPDTLDPRDMCVLNPLREPFAKKE 1099
Query: 280 CGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDHDILCKALASYVAACQAAGV 337
C L F CH V F+ C+ D C GGD + C ++++Y C GV
Sbjct: 1100 CSILLSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGV 1156
Query: 338 VIEDWRAQVGCEITC 352
+ DWR C C
Sbjct: 1157 AV-DWRTPRLCPYDC 1170
Score = 64.3 bits (155), Expect = 8e-10
Identities = 112/432 (25%), Positives = 157/432 (36%), Gaps = 65/432 (15%)
Query: 67 CLPNYEATCW--LWGDPHYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLTPFTVTTKNE 124
C P +E C ++ D + +FDG Y+L+ + + LT + K+
Sbjct: 2029 CCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS-----PDEMLTVHVLDCKSA 2083
Query: 125 NRGN---PAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGAS 181
N G+ P V ++ + L ++I + KV V+ PVS RI
Sbjct: 2084 NLGHLNWPPFCLV-MLNMTHLAHQVTIDRFN-RKVTVDLQPVWPPVSRYGFRIEDTGHMY 2141
Query: 182 KALLVADFGLQVSYDWNWR-VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTL----- 235
L +D +Q + V+ + S G GLCG D + ND +G++
Sbjct: 2142 MILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLKDGSVVGGAE 2199
Query: 236 --APSIPIWG--GSWRAPGWDPLCWDECRGS-CPTCPEDRLEQYEGPGFCGPLAPGTGGP 290
AP + W S + G D C + C C L +
Sbjct: 2200 DPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPC----------------LRMVSNRT 2243
Query: 291 FTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVVIEDWRAQVGCEI 350
F+ CH VPPESF + + D C AL YVA C V IE WR C
Sbjct: 2244 FSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCIE-WRRSDYCPF 2298
Query: 351 TCPENSHYEVCGPPC--PASCPSP--APLTTPAVCEGPCVEGCQCDAGFVL---SADRCV 403
C +S Y+ C C P +C PL P C+ EGC C G +L + C+
Sbjct: 2299 LCSSDSTYQACVTACEPPKTCQDGILGPL-DPEHCQ-VLGEGCVCSEGTILHRRHSALCI 2356
Query: 404 PLNNGCGCWANGTYHEAGSEFW---ADGTCSQWCRCGP-----GGGSLVCTPASC-GLGE 454
P C C + A E W G C C+ G P SC GE
Sbjct: 2357 P-EAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGE 2415
Query: 455 VCGLLPSGQHGC 466
V LLP+ C
Sbjct: 2416 VALLLPTKDPCC 2427
Score = 32.7 bits (73), Expect = 2.5
Identities = 26/96 (27%), Positives = 33/96 (34%), Gaps = 17/96 (17%)
Query: 1121 CPAHSHYSICT-----------RTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCI 1169
CPA + C+ RTC+ LS C GC C L C
Sbjct: 811 CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLS--VSARGPCLSGCACPQGLLRHGDACF 868
Query: 1170 PVQDCGCTHNGR-YLPVNSSLLTSDCSERCSCSSSS 1204
++C CT G+ Y P + S C C C S
Sbjct: 869 LPEECPCTWKGKEYFP--GDQVMSPC-HTCVCQRGS 901
>gi|239744298 PREDICTED: otogelin isoform 1 [Homo sapiens]
Length = 2924
Score = 297 bits (761), Expect = 4e-80
Identities = 305/1178 (25%), Positives = 452/1178 (38%), Gaps = 205/1178 (17%)
Query: 69 PNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLTPFTVTTKNENR-G 127
P ++ C WG H +FDG + G +Y L +G F++ N+ + G
Sbjct: 145 PERDSICRAWGQHHVETFDGLYYYLSGKGSYTL-----VGRHEPEGQSFSIQVHNDPQCG 199
Query: 128 NPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVA 187
+ + R V++ +G IH + +V G+ LP + R+ Q A ++
Sbjct: 200 SSPYTCSRAVSLFFVGEQ-EIHLAK--EVTHGGMRVQLPHVMGSARLQ--QLAGYVIVRH 254
Query: 188 DFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWR 247
+++D V + + G GLCGN + +P +D V +G L + + SW+
Sbjct: 255 QSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ 314
Query: 248 --APGWDP------LCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVP 299
AP P L C P + EQ E L P PF CHA+V
Sbjct: 315 EQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEAL-----LRP----PFDACHAYVS 365
Query: 300 PESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVVIEDWRAQV-GCEITCPENSH- 357
P F C D+C GD C+ALA Y AC AG ++ WR Q+ C + C E +
Sbjct: 366 PLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFT 425
Query: 358 YEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTY 417
Y C CPASC P + E CV+GC C G + CV C C +GT
Sbjct: 426 YNECIACCPASC---HPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE-CPCEFHGTL 481
Query: 418 HEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAW 477
+ GS D C+ C C G C+ A C AEC
Sbjct: 482 YPPGSVVKED--CNT-CTC--TSGKWECSTAVC--------------------PAECSVT 516
Query: 478 GDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTL 536
GD H+ T DG R+ F TC+Y+L+ + FTVT+ N G +Q + +SV++
Sbjct: 517 GDIHFTTFDGRRYTFPATCQYILA-----KSRSSGTFTVTLQNAPCGLNQDGACVQSVSV 571
Query: 537 QIY---NHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDG 593
++ +TL+ L D + P+ D+ LS + V T G+ + +D
Sbjct: 572 ILHQDPRRQVTLTQAGD-VLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDR 630
Query: 594 DSF-VRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQGCGE 644
+ + L+V + GLCG +N + DD + G P W+ A C
Sbjct: 631 EGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA--CSP 688
Query: 645 CVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGH 704
VS PC Q + AC V+ T APC + P YF+ C DAC+ G
Sbjct: 689 LVSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDACRC-GQ 745
Query: 705 PGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEG 764
P LC +A Y C+ G + R C L C A Y C C +C L++PE
Sbjct: 746 P-CLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEA 804
Query: 765 C---------ESACREGCVC--DAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPG--- 810
C C EGC C D D CVP QC C G YP G+ P
Sbjct: 805 CGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGH 864
Query: 811 -------PECERRCECG--PGGHV-----------------TCQE--------------- 829
C+ R P G V TC++
Sbjct: 865 CHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLS 924
Query: 830 -----------GAACGPHEECRL----------EDGVQACHATGCGR------------- 855
G AC EEC + + CH C R
Sbjct: 925 GCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPCAST 984
Query: 856 CLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEK---NAAGDLQRLLV 912
C A G HY T DG +D G+C L + D FS+++E ++G + R
Sbjct: 985 CTAYGDRHYRTFDGLPFDFVGACKVHLVK----STSDVSFSVIVENVNCYSSGMICR--- 1037
Query: 913 TVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGR-------NMVLQTTKGLRLLFD 965
+ +S+ G + V + P + E +V + + LL+D
Sbjct: 1038 ----KFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWD 1093
Query: 966 GDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCG 1025
+ + ++G+L GLCGNF+ ++ P ++ + FG++W ++ C
Sbjct: 1094 QRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSW----AAVECP 1149
Query: 1026 EGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDL--CAQ 1083
+ P+ +C+ + + C L + F C V+ + ++ C+ D C+Q
Sbjct: 1150 DTLDPR--DMCVLNPLREPFAKKECSILLSE--VFEICHPVVDVTWFYSNCLTDTCGCSQ 1205
Query: 1084 KGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHC 1121
GD C S++AY C GVAV WRT CP C
Sbjct: 1206 GGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1242
Score = 254 bits (649), Expect = 4e-67
Identities = 233/821 (28%), Positives = 317/821 (38%), Gaps = 90/821 (10%)
Query: 440 GGSLVCTPASCGLGEVCGLLPSGQ--HGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCE 497
GG V PA C P Q + P + C+AWG H T DG + G
Sbjct: 116 GGECV-HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGS 174
Query: 498 YLLSAPCHGPPLGAENFTVTVANEHR-GSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD 556
Y L H P ++F++ V N+ + GS + +R+V+L +++
Sbjct: 175 YTLVGR-HEPE--GQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQ---EIHLAKEVTHG 228
Query: 557 GVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNY 616
G+ V LP + S L+G V+V S +LA+DG S V +++ GLCGN
Sbjct: 229 GMRVQLPHVMGSARLQQLAGY-VIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNN 287
Query: 617 NQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCT------PEQQESFGGPDACGV 670
N DP DDL GK V E P P T P Q++ G GV
Sbjct: 288 NADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQ--GV 345
Query: 671 ISATDGPLAP----CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQL 726
+ L P CH V P + C D CQ G C A+A Y AC AG L
Sbjct: 346 YEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 405
Query: 727 GEWRRP-DFCPLQCPAHSH-YELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGD 784
WR C + C + Y C CP SC ++ E AC +GC C G +
Sbjct: 406 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDG 465
Query: 785 TCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDG 844
CV +C C G YP PG + C C G
Sbjct: 466 GCVAPAECPCEFHGTLYP------PGSVVKEDCNT-------------------CTCTSG 500
Query: 845 VQACHATGC-GRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNA 903
C C C G IH+ T DGR Y +C Y+LA+ F++ L+
Sbjct: 501 KWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAK----SRSSGTFTVTLQNAP 556
Query: 904 AG---------DLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVL 954
G + +L + V+L Q V + + +P ++ L
Sbjct: 557 CGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFL 616
Query: 955 Q--TTKGLRLLFDGDA-HLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETF 1011
+ T G+R+L+D + L + + + GLCG FNGN DDF+ P G S+ + F
Sbjct: 617 RVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLF 676
Query: 1012 GAAWRVPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSE 1071
G +W+ + G C V L + A Y S +AC L FA C A LSP
Sbjct: 677 GNSWKTLSACSPLVSGSPLDPCDVHL--QAASY-SVQACSVLTGEM--FAPCSAFLSPVP 731
Query: 1072 YFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICT 1131
YF QC D C + + LC +LA Y C+ G+ V C L C A YS C
Sbjct: 732 YFEQCRRDAC--RCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCV 789
Query: 1132 RTCQGSCAALSGLTGC---------TTRCFEGCEC-DDRFLLSQG-VCIPVQDCGCTHNG 1180
C +C L+ C C EGC C D +L +Q +C+P C C G
Sbjct: 790 APCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQG 849
Query: 1181 RYLPVNSSLLTSDCSERCSCSS---SSGLTCQAAGCPPGRV 1218
P S + S C C S AA CP G+V
Sbjct: 850 VDYPPGDSDIPS--LGHCHCKDGVMSCDSRAPAAACPAGQV 888
Score = 161 bits (407), Expect = 5e-39
Identities = 154/588 (26%), Positives = 227/588 (38%), Gaps = 47/588 (7%)
Query: 816 RCECGPGGHVTCQEGAACGPHE--ECRLEDGV----QACHATGCGR---CLANGGIHYIT 866
R +C P +C G C +CR + Q + G R C A G H T
Sbjct: 102 RAKCAPSYLFSCFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVET 161
Query: 867 LDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRL-------LVTVAGQVV 919
DG Y L G SY L V +P + FSI + + L V Q +
Sbjct: 162 FDGLYYYLSGKGSYTL--VGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEI 219
Query: 920 SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFR 979
LA+ +VT G V LP +G R+ ++++ L +DG + + + +
Sbjct: 220 HLAK--EVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELL 277
Query: 980 GRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEGCGPQGCPVCLAE 1039
G GLCGN N + DD V +G V F +W+ ++ G P CL +
Sbjct: 278 GWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQ 337
Query: 1040 ETAPYES-NEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYT 1098
+ E C L P PF C A +SP + C DLC GD A CR+LA Y
Sbjct: 338 NPGTMQGVYEQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYA 395
Query: 1099 AACQAAGVAVKPWRTD-SFCPLHCPAHSH-YSICTRTCQGSCAALSGLTGCTTRCFEGCE 1156
AC AG ++ WRT C +HC + Y+ C C SC + C +GC
Sbjct: 396 RACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCY 455
Query: 1157 CDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPG 1216
C + + G C+ +C C +G P S++ DC+ C+C+S C A CP
Sbjct: 456 CPNGLIFEDGGCVAPAECPCEFHGTLYP-PGSVVKEDCN-TCTCTSGK-WECSTAVCP-- 510
Query: 1217 RVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYR 1276
AE C ++ + TTFDG R + Y L+ T+
Sbjct: 511 ------AE----------CSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQN 554
Query: 1277 VVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDG 1336
+ ++V + VTLT V + +P + + R
Sbjct: 555 APCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSV 614
Query: 1337 SLLVRQKAGVQVWLGANG-KVAVIVSNDHAGKLCGACGNFDGDQTNDW 1383
L VR GV+V G ++ + V G CG F+G+ +D+
Sbjct: 615 FLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDF 662
Score = 94.0 bits (232), Expect = 9e-19
Identities = 118/502 (23%), Positives = 190/502 (37%), Gaps = 87/502 (17%)
Query: 755 SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLH----DGRYYPLGEVFYPG 810
S P+LS EG A + + TCVP+ + C+ +G+ + + +
Sbjct: 2025 SAPALSIVEGLAEALATTTEAN-----TSTTCVPIAEQDCVRHICLEGQLIRVNQSQHC- 2078
Query: 811 PECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGR 870
P+ CG G G C P EC AC RC + ++T DG
Sbjct: 2079 PQGAAPPRCGILGLAVRVGGDRCCPLWEC-------AC------RCSIFPDLSFVTFDGS 2125
Query: 871 VYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRL-----------LVTVAGQVV 919
L Y+L+Q DE ++ + + +L L + +A QV
Sbjct: 2126 HVALFKEAIYILSQ-----SPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVT 2180
Query: 920 SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLM---SIPS 976
++VTVD + V PV+ R+ G ++ T +++ + + L++ S S
Sbjct: 2181 IDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTS 2240
Query: 977 PFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVET---FGAAWRVPGSSKGCGE------G 1027
+G GLCG +G+ ++D L +GS E F +W+VP S G+
Sbjct: 2241 KAQGH--GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDS 2298
Query: 1028 CGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDK 1087
C C CL + AC + P+ + C+ + ++Y +Q
Sbjct: 2299 CATTDCSPCL--RMVSNRTFSACHRFVPPE---SFCELWIRDTKYVQQP----------- 2342
Query: 1088 AFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTG- 1146
C +L Y A C V ++ WR +CP C + S Y C C+ G+ G
Sbjct: 2343 ---CVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGP 2398
Query: 1147 -----CTTRCFEGCECDDRFLLSQ---GVCIPVQDCGCTHN---GRYLPVNSSLLTSDCS 1195
C EGC C + +L + +CIP C CT + R L + S C
Sbjct: 2399 LDPEHCQV-LGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCC 2457
Query: 1196 ERCSCSSSSGLTCQAAGCPPGR 1217
+ C + + GCP R
Sbjct: 2458 QH-QCQAPDTIVPVDLGCPSPR 2478
Score = 84.7 bits (208), Expect = 6e-16
Identities = 105/415 (25%), Positives = 157/415 (37%), Gaps = 79/415 (19%)
Query: 447 PASCGLGEVCGL-LPSGQHGCQPV--STAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAP 503
P CG + GL + G C P+ C + D +VT DG Y+LS
Sbjct: 2084 PPRCG---ILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS 2140
Query: 504 -----------CHGPPLGAEN---FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSAR- 548
C LG N F + + N VT+ +N +T+ +
Sbjct: 2141 PDEMLTVHVLDCKSANLGHLNWPPFCLVMLN------MTHLAHQVTIDRFNRKVTVDLQP 2194
Query: 549 -WPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRL----RVPA 603
WP + F+++ H ++ + T S + + + S + + +
Sbjct: 2195 VWPPVSRYG-------FRIEDTGHMYM------ILTPSDIQIQWLHSSGLMIVEASKTSK 2241
Query: 604 AYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECV-SKPCPSPCTPEQQESF 662
A LCG+C D A+DL G VGGA+ + S PS T Q F
Sbjct: 2242 AQGHGLCGICDG---DAANDLTLKDGSV----VGGAEDPAPFLDSWQVPSSLTSVGQTRF 2294
Query: 663 GGPDACGVISAT-------DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATY 715
PD+C + + + CH VPP + + + D VQ C A+ Y
Sbjct: 2295 R-PDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVY 2349
Query: 716 VAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSC--PVSCP----SLSAPEGCESAC 769
VA C + EWRR D+CP C + S Y+ C +C P +C PE C+
Sbjct: 2350 VAMCHKFHVCI-EWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQ-VL 2407
Query: 770 REGCVCDAGFVL---SGDTCVPVGQCGCLHD-GRYYPLGEVFYPGPE--CERRCE 818
EGCVC G +L C+P +C C G LGE + C+ +C+
Sbjct: 2408 GEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQ 2462
Score = 80.9 bits (198), Expect = 8e-15
Identities = 77/315 (24%), Positives = 117/315 (37%), Gaps = 43/315 (13%)
Query: 46 PCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTG 105
PCH C ++G L +TC +GD HY +FDG FDF G C L
Sbjct: 963 PCHTCVC-------QRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHL---- 1011
Query: 106 CLGVSTQGLTPFTVTTKNENRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTAL 165
V + F+V +N N + + + +++ +G ++ + D+ G
Sbjct: 1012 ---VKSTSDVSFSVIVENVNCYSSGMICRKFISI-NVGNSLIVFDDDSG--------NPS 1059
Query: 166 PVSVADGRISVAQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDR 222
P S D + V + F + + +D V V + G + GLCGN D
Sbjct: 1060 PESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDL 1119
Query: 223 NPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSC---PTCPEDRLEQYEGPGF 279
N+ P + +G SW A EC + C + L +
Sbjct: 1120 KTINEMRTPENLELTNPQEFGSSWAAV--------ECPDTLDPRDMCVLNPLREPFAKKE 1171
Query: 280 CGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDHDILCKALASYVAACQAAGV 337
C L F CH V F+ C+ D C GGD + C ++++Y C GV
Sbjct: 1172 CSILLSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGV 1228
Query: 338 VIEDWRAQVGCEITC 352
+ DWR C C
Sbjct: 1229 AV-DWRTPRLCPYDC 1242
Score = 64.3 bits (155), Expect = 8e-10
Identities = 112/432 (25%), Positives = 157/432 (36%), Gaps = 65/432 (15%)
Query: 67 CLPNYEATCW--LWGDPHYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLTPFTVTTKNE 124
C P +E C ++ D + +FDG Y+L+ + + LT + K+
Sbjct: 2101 CCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS-----PDEMLTVHVLDCKSA 2155
Query: 125 NRGN---PAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGAS 181
N G+ P V ++ + L ++I + KV V+ PVS RI
Sbjct: 2156 NLGHLNWPPFCLV-MLNMTHLAHQVTIDRFN-RKVTVDLQPVWPPVSRYGFRIEDTGHMY 2213
Query: 182 KALLVADFGLQVSYDWNWR-VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTL----- 235
L +D +Q + V+ + S G GLCG D + ND +G++
Sbjct: 2214 MILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLKDGSVVGGAE 2271
Query: 236 --APSIPIWG--GSWRAPGWDPLCWDECRGS-CPTCPEDRLEQYEGPGFCGPLAPGTGGP 290
AP + W S + G D C + C C L +
Sbjct: 2272 DPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPC----------------LRMVSNRT 2315
Query: 291 FTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVVIEDWRAQVGCEI 350
F+ CH VPPESF + + D C AL YVA C V IE WR C
Sbjct: 2316 FSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCIE-WRRSDYCPF 2370
Query: 351 TCPENSHYEVCGPPC--PASCPSP--APLTTPAVCEGPCVEGCQCDAGFVL---SADRCV 403
C +S Y+ C C P +C PL P C+ EGC C G +L + C+
Sbjct: 2371 LCSSDSTYQACVTACEPPKTCQDGILGPL-DPEHCQ-VLGEGCVCSEGTILHRRHSALCI 2428
Query: 404 PLNNGCGCWANGTYHEAGSEFW---ADGTCSQWCRCGP-----GGGSLVCTPASC-GLGE 454
P C C + A E W G C C+ G P SC GE
Sbjct: 2429 P-EAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGE 2487
Query: 455 VCGLLPSGQHGC 466
V LLP+ C
Sbjct: 2488 VALLLPTKDPCC 2499
Score = 32.7 bits (73), Expect = 2.5
Identities = 26/96 (27%), Positives = 33/96 (34%), Gaps = 17/96 (17%)
Query: 1121 CPAHSHYSICT-----------RTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCI 1169
CPA + C+ RTC+ LS C GC C L C
Sbjct: 883 CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLS--VSARGPCLSGCACPQGLLRHGDACF 940
Query: 1170 PVQDCGCTHNGR-YLPVNSSLLTSDCSERCSCSSSS 1204
++C CT G+ Y P + S C C C S
Sbjct: 941 LPEECPCTWKGKEYFP--GDQVMSPC-HTCVCQRGS 973
>gi|151301154 mucin 6, gastric [Homo sapiens]
Length = 2439
Score = 281 bits (719), Expect = 3e-75
Identities = 309/1235 (25%), Positives = 442/1235 (35%), Gaps = 223/1235 (18%)
Query: 75 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLTPFTVTTKNENRGNPAVSYV 134
C WG H+ +FD +DF GTCNY+ A T F+V + R P S
Sbjct: 45 CSTWGAGHFSTFDHHVYDFSGTCNYIFAAT-----CKDAFPTFSV----QLRRGPDGSIS 95
Query: 135 RVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVS 194
R++ LG ++ + I V+ GV++ LP + ++G G S L+ L++
Sbjct: 96 RIIV--ELGASVVTVSEAIISVKDIGVIS-LPYT-SNGLQITPFGQSVRLVAKQLELELE 151
Query: 195 YDW--NWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGT-LAPSIPIWGGSWRAPGW 251
W + + V + Y G +CGLCGN D N+ V G L P PG
Sbjct: 152 VVWGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEPHKFAALQKLDDPG- 210
Query: 252 DPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV 311
+C + P + Q + C L V E F C DV
Sbjct: 211 -EIC------TFQDIPSTHVRQAQHARICTQLLT-----LVAPECSVSKEPFVLSCQADV 258
Query: 312 CMGG--GDHDILCKALASYVAACQAAGVVIEDWRAQVGCEI-TCPENSHYEVCGPPCPAS 368
G + C L+ Y C G + WR+ C + CP N Y+ CG C +
Sbjct: 259 AAAPQPGPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSACVKT 318
Query: 369 CPSPAPLTTPAVCEGPCVEGCQCDAGFVLSA----DRCVPLNNGCGCWANGTYHEAGSEF 424
C +P C C GC C G VL+ CVP+ C C +G + G
Sbjct: 319 CSNPQHS-----CSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQ-CPCVLHGAMYAPGEVT 372
Query: 425 WADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVT 484
A Q CRC G VCT C C G T
Sbjct: 373 IA---ACQTCRCTLG--RWVCTERPC--------------------PGHCSLEGGSFVTT 407
Query: 485 LDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLT 544
D + F GTC Y+L P L + + V ++ S + + +V +
Sbjct: 408 FDARPYRFHGTCTYIL---LQSPQLPEDGALMAVYDKSGVSHSETSLVAVVYLSRQDKIV 464
Query: 545 LSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAA 604
+S + +G LP++ ++ + + + T+ GL L + V
Sbjct: 465 ISQ--DEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVTVG 522
Query: 605 --YAASLCGLCGNYNQDPADDLKAVGGKPAG--------WQVGGAQGCGECVSKPCPSPC 654
+ GLCGN+N D DD G G W+ G E + PC
Sbjct: 523 PQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWRAGNCPAALERET----DPC 578
Query: 655 TPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVAT 714
+ Q C ++ T CH V PA +++ C+ AC + +C A+
Sbjct: 579 SMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQACNYEETFPHICAALGD 638
Query: 715 YVAACQAAGAQLGEWRRP-DFCPLQCPAHSHYELCGDSCPVSCPSLS--APEGCESACR- 770
YV AC G L WR D C + C ++ + +C +C SLS A E SA
Sbjct: 639 YVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLSLSDRATECHHSAVPV 698
Query: 771 EGCVC-DAGFVLSGDTCVPVGQCGCLHDGRYYPL----------------GEVFYP---- 809
+GC C D ++ CV QC C+ +G + L G + P
Sbjct: 699 DGCNCPDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVINGITCHCINGRLSCPQRPQ 758
Query: 810 -----------------------GPECERRCE------------CGPGGHVTCQEG---- 830
G C C+ C PG C EG
Sbjct: 759 MFLASCQAPKTFKSCSQSSENKFGAACAPTCQMLATGVACVPTKCEPG--CVCAEGLYEN 816
Query: 831 --AACGPHEECRLE-DGVQ---------ACHATGCGR--------------CLANGGIHY 864
C P EEC E GV C C R C G H
Sbjct: 817 ADGQCVPPEECPCEFSGVSYPGGAELHTDCRTCSCSRGRWACQQGTHCPSTCTLYGEGHV 876
Query: 865 ITLDGRVYDLHGSCSYVLA-QVCHPKPGDEDFSIVLEK----NAAGDLQRLLVTVAGQVV 919
IT DG+ + G+C Y+LA VC F I+ E N+ R + G +
Sbjct: 877 ITFDGQRFVFDGNCEYILATDVCGVNDSQPTFKILTENVICGNSGVTCSRAIKIFLGGLS 936
Query: 920 SLAQGQQVTVDGEA--VALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSP 977
+ + TV GE V L V G + + + + + L L+++ +L+ I
Sbjct: 937 VVLADRNYTVTGEEPHVQLGVTPGALSLVVD---ISIPGRYNLTLIWNRHMTILIRIARA 993
Query: 978 FRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEGCGPQGCPVCL 1037
+ LCGLCGNFNGN DDF + ASS +W+ S CG+ C
Sbjct: 994 SQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSWK---ESPLCGDVSFV--TDPCS 1048
Query: 1038 AEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCA--QKGDKAFLCRSLA 1095
+ C + + FATC + + Y+ CV D C GD LC ++A
Sbjct: 1049 LNAFRRSWAERKCSVINSQ--TFATCHSKVYHLPYYEACVRDACGCDSGGDCECLCDAVA 1106
Query: 1096 AYTAACQAAGVAVKPWRTDSFCPLHCPAHS--------------------HYSICTRTCQ 1135
AY AC GV V WRT +FCP++C ++ HY C Q
Sbjct: 1107 AYAQACLDKGVCV-DWRTPAFCPIYCGFYNTHTQDGHGEYQYTQEANCTWHYQPCLCPSQ 1165
Query: 1136 GSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIP 1170
S + GC C D+ F +GVC+P
Sbjct: 1166 PQSVPGSNIEGC-----YNCSQDEYFDHEEGVCVP 1195
Score = 261 bits (668), Expect = 3e-69
Identities = 257/1054 (24%), Positives = 403/1054 (38%), Gaps = 195/1054 (18%)
Query: 473 ECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTR 532
+C WG H+ T D H +DF GTC Y+ +A C F+V + GS +
Sbjct: 44 QCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKD---AFPTFSVQLRRGPDGSIS----- 95
Query: 533 SVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSL--A 590
+ +++ +T+S + GV ++LP+ + L + +V L L
Sbjct: 96 RIIVELGASVVTVSEAIISVKDI-GV-ISLPYTSNGLQITPFGQSVRLVAKQLELELEVV 153
Query: 591 FDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGA----QGCGE-C 645
+ DS + + V Y +CGLCGN++ ++ + GK A GE C
Sbjct: 154 WGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEPHKFAALQKLDDPGEIC 213
Query: 646 VSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLD--ACQVQG 703
+ PS + Q + C + P V + C D A G
Sbjct: 214 TFQDIPSTHVRQAQHA----RICTQLLTLVAPECS----VSKEPFVLSCQADVAAAPQPG 265
Query: 704 HPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPL-QCPAHSHYELCGDSCPVSCPSLSAP 762
C ++ Y C G + WR P C + QCPA+ Y+ CG +C +C +
Sbjct: 266 PQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSACVKTCSN--PQ 323
Query: 763 EGCESACREGCVCDAGFVLS----GDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCE 818
C S+C GC C G VL+ TCVPV QC C+ G Y GEV
Sbjct: 324 HSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTI---------- 373
Query: 819 CGPGGHVTCQEGAACGPHEECRLEDGVQACHATGC-GRCLANGGIHYITLDGRVYDLHGS 877
AAC + CR G C C G C GG T D R Y HG+
Sbjct: 374 ------------AAC---QTCRCTLGRWVCTERPCPGHCSLEGGSFVTTFDARPYRFHGT 418
Query: 878 CSYVLAQVCHPK-PGDEDFSIVLEKNAAGDLQRLLVTVA----GQVVSLAQGQQVTVDGE 932
C+Y+L Q P+ P D V +K+ + LV V + ++Q + VT +GE
Sbjct: 419 CTYILLQ--SPQLPEDGALMAVYDKSGVSHSETSLVAVVYLSRQDKIVISQDEVVTNNGE 476
Query: 933 AVALPVAVGRVRVTAE-GRNMVLQTTKGLRLLFDGDA--HLLMSIPSPFRGRLCGLCGNF 989
A LP + V + ++ + T+ GL L+ +++ FRG+ GLCGNF
Sbjct: 477 AKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNF 536
Query: 990 NGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEGCGPQGCPVCLAEETAPYESNEA 1049
NG+ +DDF G A + F +WR CP L ET P ++
Sbjct: 537 NGDTTDDFTTSMGIAEGTASLFVDSWRAGN-------------CPAALERETDPCSMSQL 583
Query: 1050 --------CGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAAC 1101
C L F C A ++P+ ++++CVY C + +C +L Y AC
Sbjct: 584 NKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQACNYEETFPHICAALGDYVHAC 643
Query: 1102 QAAGVAVKPWRTD-SFCPLHCPAHSHYSICTRTCQGSCAALSG-LTGC--TTRCFEGCEC 1157
GV + WR+ C + C ++ +S ++ C+ +C +LS T C + +GC C
Sbjct: 644 SLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLSLSDRATECHHSAVPVDGCNC 703
Query: 1158 DDRFLLSQ-GVCIPVQDCGCTHNG-RYLPVNSSLLTSDCSERC----------------- 1198
D L+Q G C+ C C G +++ S + + + C
Sbjct: 704 PDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVINGITCHCINGRLSCPQRPQMFLAS 763
Query: 1199 --------SCSSSS-----------------GLTCQAAGCPPGRVC-------------- 1219
SCS SS G+ C C PG VC
Sbjct: 764 CQAPKTFKSCSQSSENKFGAACAPTCQMLATGVACVPTKCEPGCVCAEGLYENADGQCVP 823
Query: 1220 -----------------EVKAEARNCWATRG------------LCVLSVGANLTTFDGAR 1250
E+ + R C +RG C L ++ TFDG R
Sbjct: 824 PEECPCEFSGVSYPGGAELHTDCRTCSCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQR 883
Query: 1251 GATTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKG 1310
Y L++ G+ ++ P ++++ E IC + F G+ + ++
Sbjct: 884 FVFDGNCEYILATDVCGVNDSQPTFKILTENVICGNSGVTCSRAIKIFLGGLSVVLADRN 943
Query: 1311 VWVNGLRVDLPAEKLASV--SVSRTPDGSLLVRQKAGVQVWLGANGKVAVIVSNDHAGKL 1368
V G + P +L ++S D S+ R + +W + + + ++ L
Sbjct: 944 YTVTG---EEPHVQLGVTPGALSLVVDISIPGRYNLTL-IW-NRHMTILIRIARASQDPL 998
Query: 1369 CGACGNFDGDQTNDWHD------SQEKPAMEKWR 1396
CG CGNF+G+ +D+ S E + W+
Sbjct: 999 CGLCGNFNGNMKDDFETRSRYVASSELELVNSWK 1032
Score = 187 bits (475), Expect = 6e-47
Identities = 217/861 (25%), Positives = 316/861 (36%), Gaps = 158/861 (18%)
Query: 50 VTCRPQETCKEQGGQGVCLPN-YEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCLG 108
VT +TC+ G+ VC C L G +FD R + F GTC Y+L + L
Sbjct: 371 VTIAACQTCRCTLGRWVCTERPCPGHCSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLP 430
Query: 109 VSTQGLTPFTVTTKNENRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVS 168
+ + + + + S V VV ++ I I +DE+ V NG LP
Sbjct: 431 EDGALMAVYDKSGVSHSE----TSLVAVVYLSRQD-KIVISQDEV--VTNNGEAKWLPYK 483
Query: 169 VADGRISVAQGASKALLVA-DFGLQVSYDWN--WRVDVTLPSSYHGAVCGLCGNMDRNPN 225
+ I+V + S L +A FGL++ ++ VT+ + G GLCGN + +
Sbjct: 484 TRN--ITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTT 541
Query: 226 NDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPT--------CPEDRLEQYEGP 277
+D G + ++ SWRA G+CP C +L +
Sbjct: 542 DDFTTSMGIAEGTASLFVDSWRA------------GNCPAALERETDPCSMSQLNKVCAE 589
Query: 278 GFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGV 337
C L TG F CHA V P F+K CV C +C AL YV AC GV
Sbjct: 590 THCSMLLR-TGTVFERCHATVNPAPFYKRCVYQACNYEETFPHICAALGDYVHACSLRGV 648
Query: 338 VIEDWRAQV-GCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFV 396
++ WR+ V C I C N+ + C +C S + T V+GC C G
Sbjct: 649 LLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLSLSDRATECHHSAVPVDGCNCPDGTY 708
Query: 397 LS----------------------ADRCVPLN-------NG------------CGCWANG 415
L+ A++ +N NG C A
Sbjct: 709 LNQKGECVRKAQCPCILEGYKFILAEQSTVINGITCHCINGRLSCPQRPQMFLASCQAPK 768
Query: 416 TYHEA--GSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVC--GLLPSGQHGCQPVST 471
T+ SE C+ C+ G + C P C G VC GL + C P
Sbjct: 769 TFKSCSQSSENKFGAACAPTCQMLATG--VACVPTKCEPGCVCAEGLYENADGQCVPPEE 826
Query: 472 AECQ---------------------------------------AWGDPHYVTLDGHRFDF 492
C+ +G+ H +T DG RF F
Sbjct: 827 CPCEFSGVSYPGGAELHTDCRTCSCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQRFVF 886
Query: 493 QGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRK 552
G CEY+L+ G F + N G+ V+ +R++ + + S+ L+ R
Sbjct: 887 DGNCEYILATDVCGVNDSQPTFKILTENVICGNSGVTCSRAIKIFLGGLSVVLA---DRN 943
Query: 553 LQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGL 612
V G + QL A D+ + L+L ++ + +R+ A LCGL
Sbjct: 944 YTVTGEEPHV--QLGVTPGALSLVVDISIPGRYNLTLIWNRHMTILIRIARASQDPLCGL 1001
Query: 613 CGNYNQDPADDLKAVGGKPAGWQVGGAQG------CGECVSKPCPSPCTPEQQESFGGPD 666
CGN+N + DD + A ++ CG+ PC+
Sbjct: 1002 CGNFNGNMKDDFETRSRYVASSELELVNSWKESPLCGDV--SFVTDPCSLNAFRRSWAER 1059
Query: 667 ACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGA 724
C VI++ A CH V Y++ C+ DAC G LC AVA Y AC G
Sbjct: 1060 KCSVINSQ--TFATCHSKVYHLPYYEACVRDACGCDSGGDCECLCDAVAAYAQACLDKGV 1117
Query: 725 QLGEWRRPDFCPLQC--------PAHSHYELCGD-SC-----PVSCPSLSAPEGCESACR 770
+ +WR P FCP+ C H Y+ + +C P CP S P+ +
Sbjct: 1118 CV-DWRTPAFCPIYCGFYNTHTQDGHGEYQYTQEANCTWHYQPCLCP--SQPQSVPGSNI 1174
Query: 771 EGCV-C--DAGFVLSGDTCVP 788
EGC C D F CVP
Sbjct: 1175 EGCYNCSQDEYFDHEEGVCVP 1195
Score = 170 bits (431), Expect = 8e-42
Identities = 157/578 (27%), Positives = 248/578 (42%), Gaps = 64/578 (11%)
Query: 840 RLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVL 899
RL+D Q A G+C G H+ T D VYD G+C+Y+ A C K FS+ L
Sbjct: 31 RLKDSPQT--APDKGQCSTWGAGHFSTFDHHVYDFSGTCNYIFAATC--KDAFPTFSVQL 86
Query: 900 EKNAAGDLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVL---QT 956
+ G + R++V + VV++++ D ++LP +++T G+++ L Q
Sbjct: 87 RRGPDGSISRIIVELGASVVTVSEAIISVKDIGVISLPYTSNGLQITPFGQSVRLVAKQL 146
Query: 957 TKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWR 1016
L +++ D+HL++ + + G++CGLCGNF+G +++FV G F A +
Sbjct: 147 ELELEVVWGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEP-HKFAALQK 205
Query: 1017 VPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQC 1076
+ GE C Q P + + C QL P + +S + C
Sbjct: 206 LDDP----GEICTFQDIP---STHVRQAQHARICTQLLTLVAP----ECSVSKEPFVLSC 254
Query: 1077 VYDLCA--QKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPL-HCPAHSHYSICTRT 1133
D+ A Q G + C +L+ Y+ C G V+ WR+ C + CPA+ Y C
Sbjct: 255 QADVAAAPQPGPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSA 314
Query: 1134 CQGSCAALSGLTGCTTRCFEGCECDDRFLL----SQGVCIPVQDCGCT-HNGRYLPVNSS 1188
C +C+ + C++ C GC C + +L + C+PV C C H Y P +
Sbjct: 315 CVKTCS--NPQHSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVT 372
Query: 1189 LLTSDCSERCSCSSSSGLTCQAAGCPPGR-VCEVKAEARNCWATRGLCVLSVGANLTTFD 1247
+ CQ C GR VC R C G C L G+ +TTFD
Sbjct: 373 I----------------AACQTCRCTLGRWVC----TERPC---PGHCSLEGGSFVTTFD 409
Query: 1248 GARGATTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVGQVHIFFQDGMVTLTP 1307
Y L + P L V + + H +T V V++ QD +V ++
Sbjct: 410 ARPYRFHGTCTYIL-LQSPQLPEDGALMAVYDKSGVSHSETSLVAVVYLSRQDKIV-ISQ 467
Query: 1308 NKGVWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQ--VWLGANGKVAVIVSNDHA 1365
++ V NG LP K +++V R L + G++ V L + V V
Sbjct: 468 DEVVTNNGEAKWLP-YKTRNITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVTVGPQFR 526
Query: 1366 GKLCGACGNFDGDQTNDWHDSQ---EKPA---MEKWRA 1397
G+ G CGNF+GD T+D+ S E A ++ WRA
Sbjct: 527 GQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWRA 564
>gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens]
Length = 1503
Score = 208 bits (529), Expect = 3e-53
Identities = 184/560 (32%), Positives = 237/560 (42%), Gaps = 85/560 (15%)
Query: 657 EQQESFG-GPDACGVISATDGPLAP----CHGLVPPAQYFQGCLLDACQVQGHPGGLCPA 711
E ESF G D C V P P CH P+ GC G P CP
Sbjct: 962 EPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPS--LVGCPPSQLLPPG-PQHCCPT 1018
Query: 712 VATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELC-GDSCP-VSCPSL---SAPEGCE 766
A ++ C + G E PD C C LC +CP +SCP + P C
Sbjct: 1019 CAEALSNC-SEGLLGSELAPPDPC-YTCQCQDLTWLCIHQACPELSCPLSERHTPPGSCC 1076
Query: 767 SACR---EGCVCDAGFVLSG-----DTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCE 818
CR + CV V SG DTC C C+ G V C+ +
Sbjct: 1077 PVCRAPTQSCVHQGREVASGERWTVDTCT---SCSCM-------AGTV-----RCQSQ-R 1120
Query: 819 CGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCL-------ANGGIHYITLDGRV 871
C P +CGP + L G +C C RCL A G HY T DGR+
Sbjct: 1121 CSP---------LSCGPDKAPALSPG--SC----CPRCLPRPASCMAFGDPHYRTFDGRL 1165
Query: 872 YDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGD-----LQRLLVTVAGQVVSLAQGQQ 926
GSCSYVLA+ CH DFS+ + + G Q + V + V L Q
Sbjct: 1166 LHFQGSCSYVLAKDCH----SGDFSVHVTNDDRGRSGVAWTQEVAVLLGDMAVRLLQDGA 1221
Query: 927 VTVDGEAVALP-VAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGL 985
VTVDG VALP + + V G ++L GL++L+DG + + +S+P ++GR CGL
Sbjct: 1222 VTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGL 1281
Query: 986 CGNFNGNWSDDFVLPNGSAASSVETFGAAWRV-PGSSKGCGEGCGPQGCPVCLAEETAPY 1044
CGNFNG DD P G S FG +W+V G G G + P A A
Sbjct: 1282 CGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPCRAAGYRARR 1341
Query: 1045 ESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCA---QKGDKAFLCRSLAAYTAAC 1101
E+N CG L++ PF+ C AV+ P +F CVYDLCA A LC +L AY + C
Sbjct: 1342 EANARCGVLKS--SPFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDALEAYASHC 1399
Query: 1102 QAAGVAVKPWRTDSFCPLHCPAHSHYSI------CTRTCQGSCAALSGLTG-CTTRCFEG 1154
+ AGV WR + C + CP + C RTC L L C C G
Sbjct: 1400 RQAGV-TPTWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLGELAAHCVRPCVPG 1458
Query: 1155 CECDDRFLLSQGVCIPVQDC 1174
C+C + + CIP + C
Sbjct: 1459 CQCPAGLVEHEAHCIPPEAC 1478
Score = 195 bits (495), Expect = 3e-49
Identities = 132/369 (35%), Positives = 174/369 (47%), Gaps = 26/369 (7%)
Query: 47 CHGVTCRPQETCKEQGGQGV--CLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATT 104
C ++C P + G CLP A+C +GDPHY +FDGR FQG+C+YVLA
Sbjct: 1121 CSPLSCGPDKAPALSPGSCCPRCLPR-PASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKD 1179
Query: 105 GCLGVSTQGLTPFTVTTKNENRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTA 164
G F+V N++RG V++ + V V + + +D G V V+G A
Sbjct: 1180 CHSG-------DFSVHVTNDDRGRSGVAWTQEVAVLLGDMAVRLLQD--GAVTVDGHPVA 1230
Query: 165 LPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNP 224
LP + + + V +L A GLQV +D +V+V++P SY G CGLCGN +
Sbjct: 1231 LPF-LQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNGFA 1289
Query: 225 NNDQVFPNGTLAPSIPIWGGSWRAPG--WDPLCWDECRGSCPTCPEDRLEQYEGPGFCGP 282
+D P G L PS +G SW+ W R P + E CG
Sbjct: 1290 QDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPCRAAGYRARREANARCGV 1349
Query: 283 LAPGTGGPFTTCHAHVPPESFFKGCVLDVCM---GGGDHDILCKALASYVAACQAAGVVI 339
L PF+ CHA VPPE FF CV D+C G LC AL +Y + C+ AGV
Sbjct: 1350 L---KSSPFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDALEAYASHCRQAGVT- 1405
Query: 340 EDWRAQVGCEITCP--ENSHYEVCGPPCPASC-PSPAPL-TTPAVCEGPCVEGCQCDAGF 395
WR C + CP ++ CGPPCP +C PL A C PCV GCQC AG
Sbjct: 1406 PTWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLGELAAHCVRPCVPGCQCPAGL 1465
Query: 396 VLSADRCVP 404
V C+P
Sbjct: 1466 VEHEAHCIP 1474
Score = 194 bits (494), Expect = 4e-49
Identities = 169/577 (29%), Positives = 235/577 (40%), Gaps = 86/577 (14%)
Query: 258 ECRGSCPTCPEDRLEQYEGPGF-----------CGPLAPGTGGPFTTCHAHVPPESFFKG 306
+C C C + + G F C P G P CH P G
Sbjct: 946 DCCPQCSDCEHEGRKYEPGESFQPGADPCEVCICEPQPEGP--PSLRCHRRQCPS--LVG 1001
Query: 307 CVLDVCMGGGDHDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCP 366
C + G C A ++ C + G++ + C ++ + CP
Sbjct: 1002 CPPSQLLPPGPQHC-CPTCAEALSNC-SEGLLGSELAPPDPCYTCQCQDLTWLCIHQACP 1059
Query: 367 A-SCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFW 425
SCP T P G C C+ + R V A E W
Sbjct: 1060 ELSCPLSERHTPP----GSCCPVCRAPTQSCVHQGREV----------------ASGERW 1099
Query: 426 ADGTCSQWCRCGPGG---GSLVCTPASCGLGEVCGLLP-SGQHGCQPVSTAECQAWGDPH 481
TC+ C C G S C+P SCG + L P S C P A C A+GDPH
Sbjct: 1100 TVDTCTS-CSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLP-RPASCMAFGDPH 1157
Query: 482 YVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNH 541
Y T DG FQG+C Y+L+ CH + +F+V V N+ RG V++T+ V + + +
Sbjct: 1158 YRTFDGRLLHFQGSCSYVLAKDCH-----SGDFSVHVTNDDRGRSGVAWTQEVAVLLGDM 1212
Query: 542 SLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRV 601
++ L + VDG VALPF + LL+ L G V++ GL + +DG S V + V
Sbjct: 1213 AVRLLQ--DGAVTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSV 1270
Query: 602 PAAYAASLCGLCGNYNQDPADDLKAVGG--KPA------GWQVGGAQGCGECVSKPCPS- 652
P +Y CGLCGN+N DDL+ G P+ WQV G +PC +
Sbjct: 1271 PGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSE----GLWPGRPCSAG 1326
Query: 653 ----PCTPEQQESFGGPDA-CGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGG 707
PC + +A CGV+ ++ P + CH +VPP +F C+ D C PG
Sbjct: 1327 REVDPCRAAGYRARREANARCGVLKSS--PFSRCHAVVPPEPFFAACVYDLCAC--GPGS 1382
Query: 708 -----LCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSH--YELCGDSCPVSCPSLS 760
LC A+ Y + C+ AG WR P C + CP ++ CG CP +C +
Sbjct: 1383 SADACLCDALEAYASHCRQAGV-TPTWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQH 1441
Query: 761 APEG-----CESACREGCVCDAGFVLSGDTCVPVGQC 792
P G C C GC C AG V C+P C
Sbjct: 1442 IPLGELAAHCVRPCVPGCQCPAGLVEHEAHCIPPEAC 1478
Score = 50.8 bits (120), Expect = 9e-06
Identities = 57/229 (24%), Positives = 85/229 (37%), Gaps = 21/229 (9%)
Query: 1166 GVCIPVQDC---GCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVK 1222
G C PV C H GR + C+ CSC + + + CQ+ C P K
Sbjct: 1073 GSCCPVCRAPTQSCVHQGREVASGERWTVDTCTS-CSCMAGT-VRCQSQRCSPLSCGPDK 1130
Query: 1223 AEARN-------CWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWY 1275
A A + C C+ + TFDG Y L+ C ++
Sbjct: 1131 APALSPGSCCPRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKDCHSGDFSVH-- 1188
Query: 1276 RVVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLP--AEKLASVSVSRT 1333
V +V + D V L + V V+G V LP E L V +
Sbjct: 1189 --VTNDDRGRSGVAWTQEVAVLLGDMAVRLLQDGAVTVDGHPVALPFLQEPLLYVELR-- 1244
Query: 1334 PDGSLLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTND 1382
++++ + G+QV +V V V + G+ CG CGNF+G +D
Sbjct: 1245 -GHTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDD 1292
Score = 46.6 bits (109), Expect = 2e-04
Identities = 67/243 (27%), Positives = 82/243 (33%), Gaps = 46/243 (18%)
Query: 640 QGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDAC 699
+G C KPCP P GP C V CH + + Q D
Sbjct: 806 EGSMRCQKKPCPPALCPHPSP---GPCFCPV----------CHSCLSQGREHQ----DGE 848
Query: 700 QVQGHPGGLCP-------AVATYVAACQAAGAQLGEWRRPDFCPL--QCPAHSHYELCGD 750
+ +G P G C V+ C +L R CP C AH G
Sbjct: 849 EFEG-PAGSCEWCRCQAGQVSCVRLQCPPLPCKLQVTERGSCCPRCRGCLAHGEEHPEGS 907
Query: 751 SC---PVSCPSLSAPEGCESACREGCVCDAGFVLSGD-TCVPVGQCG-CLHDGRYYPLGE 805
+C S EG + R C+ G C P QC C H+GR Y GE
Sbjct: 908 RWVPPDSACSSCVCHEGVVTCARIQCISSCAQPRQGPHDCCP--QCSDCEHEGRKYEPGE 965
Query: 806 VFYPGPE-CE-RRCECGPGGHVT-------CQEGAACGPHEECRLEDGVQACHATGCGRC 856
F PG + CE CE P G + C C P + L G Q C T C
Sbjct: 966 SFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQ--LLPPGPQHCCPT-CAEA 1022
Query: 857 LAN 859
L+N
Sbjct: 1023 LSN 1025
Score = 42.0 bits (97), Expect = 0.004
Identities = 69/258 (26%), Positives = 85/258 (32%), Gaps = 54/258 (20%)
Query: 214 CGLCGNMDRNPNNDQVFPNGTLAPSIPI-WGGSWR------APGWDPL-----CWDECRG 261
C C + + + FP+ T A + + W GS AP P C +C G
Sbjct: 659 CDGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAPALCPFPARGDCCPDCDG 718
Query: 262 SCPTCPEDRLEQYEGPGFCGP--LAPGTGGPFTTCHAHV--PPESFFKGCVLDVCMGGGD 317
C E L E P P L GG F TC PP GC + G
Sbjct: 719 -CEYLGESYLSNQEFPDPREPCNLCTCLGG-FVTCGRRPCEPP-----GCSHPLIPSG-- 769
Query: 318 HDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTT 377
H Y A+G + D TC E S P PA CP P+P
Sbjct: 770 HCCPTCQGCRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPCPPALCPHPSP--- 826
Query: 378 PAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCG 437
GPC C ++ C + G H+ G EF +WCRC
Sbjct: 827 -----GPCF---------------CPVCHS---CLSQGREHQDGEEFEGPAGSCEWCRCQ 863
Query: 438 PGGGSLV---CTPASCGL 452
G S V C P C L
Sbjct: 864 AGQVSCVRLQCPPLPCKL 881
Score = 41.2 bits (95), Expect = 0.007
Identities = 38/124 (30%), Positives = 46/124 (37%), Gaps = 31/124 (25%)
Query: 351 TCPENSHYEVCGPP---CPASCPSPAP-------LTTPAVCEGPCVEGCQCDAGFVLSAD 400
+C E + E C PP CP C TTP PC C+C G +
Sbjct: 172 SCSELNCLESCTPPGECCPICCTEGGSHWEHGQEWTTPG---DPC-RICRCLEGHIQCRQ 227
Query: 401 R-CV--------PLNNGC-----GCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCT 446
R C PL C GC+ NG H +G + CS CRC GS+ C
Sbjct: 228 RECASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSGDPCSH-CRC--ANGSVQCE 284
Query: 447 PASC 450
P C
Sbjct: 285 PLPC 288
Score = 37.7 bits (86), Expect = 0.078
Identities = 65/243 (26%), Positives = 82/243 (33%), Gaps = 62/243 (25%)
Query: 641 GCGECVSKPCPSPCTPEQQ-----ESFGGP-DACGVISATDG---------PLAPCHGLV 685
G G+C + CP C E++ ESF P D C +G P APC +
Sbjct: 473 GPGQCCPR-CPD-CILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPL 530
Query: 686 PPAQYFQGCLLDACQVQGHPGGLC---PAVATYVAACQAAGAQLGEWRRPDFCPLQCPAH 742
P C A + +P G P+ + C + Q R PL CP
Sbjct: 531 PGTCCPNDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARR---CVPLPCP-- 585
Query: 743 SHYELCGDSCPVSCPSLSAPEGCE-----------------SACREGCVCDAGFVLSGDT 785
L G+ CP CP AP GC CR C+C G V
Sbjct: 586 EPVLLPGECCP-QCP---APAGCPRPGAAHARHQEYFSPPGDPCRR-CLCLDGSVSCQRL 640
Query: 786 CVPVGQC-------------GCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAA 832
P C GCL+ G+ + GE F C C G V+C E A
Sbjct: 641 PCPPAPCAHPRQGPCCPSCDGCLYQGKEFASGERFPSPTAACHLCLCWEGS-VSC-EPKA 698
Query: 833 CGP 835
C P
Sbjct: 699 CAP 701
Score = 36.2 bits (82), Expect = 0.23
Identities = 34/108 (31%), Positives = 42/108 (38%), Gaps = 16/108 (14%)
Query: 762 PEGCE---SACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCE 818
PEG AC CVC G G GC +G+ Y GE F P+ C
Sbjct: 104 PEGARWEPDACT-ACVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNGETF--SPDACTTCR 160
Query: 819 CGPGGHVTCQEGAACGPHEECRLEDGVQACHATG--CGRCLANGGIHY 864
C G V CQ GP C + +++C G C C GG H+
Sbjct: 161 CLTGA-VQCQ-----GP--SCSELNCLESCTPPGECCPICCTEGGSHW 200
Score = 35.8 bits (81), Expect = 0.30
Identities = 118/496 (23%), Positives = 154/496 (31%), Gaps = 95/496 (19%)
Query: 389 CQCDAGFVLSADRCVP---LNNGCGCWANGTYHEAGSEFWADGTCSQWCRC--------G 437
C C G A C P L + GC NG + G F D + CRC G
Sbjct: 117 CVCQDG----AAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTT--CRCLTGAVQCQG 170
Query: 438 PGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVT--LDGHRFDFQGT 495
P L C + GE C + + + G E GDP + L+GH Q
Sbjct: 171 PSCSELNCLESCTPPGECCPICCT-EGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRE 229
Query: 496 CEYLLSAPCHGPP---LGAENFTVTVANEHRGSQAV------SYTRSVTLQIYNHSLT-- 544
C L P P + EHR + V S+ R + L
Sbjct: 230 CASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPCP 289
Query: 545 -LSARWPRKLQ------VDGV-FVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSF 596
+ R P K+ DG + +Q G V + +G + +
Sbjct: 290 PVPCRHPGKIPGQCCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQECP 349
Query: 597 VRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCTP 656
V P A AS LC D + + V +P G + C CV +
Sbjct: 350 V---TPCALPASGRQLCPACELDGEEFAEGVQWEPDG------RPCTACVCQD------- 393
Query: 657 EQQESFGGPDACGVISATDGPLAPC-HGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATY 715
G CG + P APC H PP C D+C
Sbjct: 394 -------GVPKCGAVLC---PPAPCQHPTQPPGACCPSC--DSCTYHSQVYANGQNFTDA 441
Query: 716 VAACQAAGAQLGE------------WRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAP- 762
+ C A Q G RP P QC + + V S S P
Sbjct: 442 DSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPRCPDCILEEEVFVDGESFSHPR 501
Query: 763 EGC-ESACREGCV---------CDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVF-YPGP 811
+ C E C+EG L G TC P GC G+ YP G F +P
Sbjct: 502 DPCQECRCQEGHAHCQPRPCPRAPCAHPLPG-TCCPNDCSGCAFGGKEYPSGADFPHPSD 560
Query: 812 ECERRCECGPGGHVTC 827
C R C C G+V C
Sbjct: 561 PC-RLCRC-LSGNVQC 574
Score = 33.5 bits (75), Expect = 1.5
Identities = 23/87 (26%), Positives = 32/87 (36%), Gaps = 11/87 (12%)
Query: 366 PASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCG--CWANGTYHEAGSE 423
P +C + LT C+GP C + C P C C G++ E G E
Sbjct: 153 PDACTTCRCLTGAVQCQGPSCSELNC-------LESCTPPGECCPICCTEGGSHWEHGQE 205
Query: 424 FWADGTCSQWCRCGPGGGSLVCTPASC 450
+ G + CRC G + C C
Sbjct: 206 WTTPGDPCRICRCLE--GHIQCRQREC 230
>gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]
Length = 2639
Score = 205 bits (521), Expect = 3e-52
Identities = 181/720 (25%), Positives = 278/720 (38%), Gaps = 144/720 (20%)
Query: 611 GLCGNYNQDPADDLKAVGGKPAGWQVGGA---QGCGECVSKP--CPSPCTPEQQESFGGP 665
GLCGN+N DD K G G A + C K PC+ + +
Sbjct: 427 GLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKLDWLDDPCSLNIESANYAE 486
Query: 666 DACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQ 725
C ++ T+ P CH V PA+Y++ C D C Q + LC A+++Y AC A G
Sbjct: 487 HWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGVM 546
Query: 726 LGEWRRPDFCPL---QCPAHSHYELCGDSCPVSCPSLSAPEGCESACRE------GCVC- 775
L WR C CP + +C +C SLS +S C E GC C
Sbjct: 547 LWGWRE-HVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSE---ADSHCLEGFAPVDGCGCP 602
Query: 776 DAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPG------------- 822
D F+ CVP+ +C C H G Y G+V E RC C G
Sbjct: 603 DHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVV---RQEERCVCRDGRLHCRQIRLIGQS 659
Query: 823 ---------------------GHVTCQEGAACGPHEEC---------RLEDGVQAC---- 848
++CQ AA H EC ++DG C
Sbjct: 660 CTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDGLMDDGRGGCVVEK 719
Query: 849 ----------HATG------CGRCLANGGI------------------HYITLDGRVYDL 874
+++G C C G HYIT DG+ YD
Sbjct: 720 ECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDF 779
Query: 875 HGSCSYVLAQ-VCHPKPGDEDFSIVLEKNAAGDL-----QRLLVTVAGQVVSLAQGQQVT 928
G CSYV Q C FSI+ E G + + + + + L +V
Sbjct: 780 DGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVV 839
Query: 929 V---DGEAVALPVAVGRVRVTAE-GRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCG 984
+ +G VA T E G+ +V++++ G+ +++D + + + ++G +CG
Sbjct: 840 IQRDEGHHVAY--------TTREVGQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCG 891
Query: 985 LCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEGCGPQGCPVCLAEETAPY 1044
LCGNF+ ++DF + SS FG +W+ + P C
Sbjct: 892 LCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTCPDVSTNPEP-----CSLNPHRRS 946
Query: 1045 ESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCA--QKGDKAFLCRSLAAYTAACQ 1102
+ + C L++ F+ C + + P ++ CV+D C+ GD C ++A+Y C
Sbjct: 947 WAEKQCSILKS--SVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECT 1004
Query: 1103 AAGVAVKPWRTDSFCPLHC----PAHS---HYSICTRTCQGSCAALSGL-TGCTTRCFEG 1154
G V WRT CP+ C P H HY C +C ++G+ + + EG
Sbjct: 1005 KEGACVF-WRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEG 1063
Query: 1155 C--EC-DDRFLLSQGV--CIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQ 1209
C C DR + + + C+ CGC + P +S+ T + + C C++SS + C+
Sbjct: 1064 CYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGASVPTEETCKSCVCTNSSQVVCR 1123
Score = 139 bits (350), Expect = 2e-32
Identities = 121/484 (25%), Positives = 191/484 (39%), Gaps = 76/484 (15%)
Query: 385 CVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLV 444
CV GC C G + + C C N + +G++ D C+ C C G V
Sbjct: 697 CVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVD--CNT-CTCKRG--RWV 751
Query: 445 CTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPC 504
CT A C HG C +G HY+T DG +DF G C Y+
Sbjct: 752 CTQAVC-------------HGT-------CSIYGSGHYITFDGKYYDFDGHCSYVAVQDY 791
Query: 505 HGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD-GVFVALP 563
G +F++ N G+ V+ ++++ + + L L + +Q D G VA
Sbjct: 792 CGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYT 851
Query: 564 FQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADD 623
G +VV +++G+ + +D + V +++ +Y ++CGLCGN++ +D
Sbjct: 852 --------TREVGQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNND 903
Query: 624 LKAVGGKPAGWQVGGAQGCGECVSKP----CPSPCTPEQQESFGGPDACGVISATDGPLA 679
++ E + P P PC+ C ++ ++ +
Sbjct: 904 FTTRDHMVVSSELDFGNSWKEAPTCPDVSTNPEPCSLNPHRRSWAEKQCSILKSS--VFS 961
Query: 680 PCHGLVPPAQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPL 737
CH V P +++ C+ D+C G C AVA+Y C GA + WR PD CP+
Sbjct: 962 ICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACV-FWRTPDLCPI 1020
Query: 738 QC----PAHS---HYELCGDSCPVSCP---------SLSAPEGCESAC-REGCVCDAGFV 780
C P H HYE CG+ +C S+S EGC C ++ + +
Sbjct: 1021 FCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDL- 1079
Query: 781 LSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTC-----------QE 829
CV +CGC + +YP G P E + C C V C Q+
Sbjct: 1080 ---KKCVTADKCGCYVEDTHYPPG-ASVPTEETCKSCVCTNSSQVVCRPEEGKILNQTQD 1135
Query: 830 GAAC 833
GA C
Sbjct: 1136 GAFC 1139
Score = 133 bits (335), Expect = 1e-30
Identities = 126/510 (24%), Positives = 193/510 (37%), Gaps = 114/510 (22%)
Query: 970 LLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEGCG 1029
L +++ +G++ GLCGNFNG DDF +G ++ F W+ S C +
Sbjct: 413 LFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSS---CHDKLD 469
Query: 1030 PQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAF 1089
P L E+A Y + C L+ + PF C + + P+EY+++C YD C + ++
Sbjct: 470 WLDDPCSLNIESANY-AEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDC 528
Query: 1090 LCRSLAAYTAACQAAGVAVKPWRTDSFCPL---HCPAHSHYSICTRTCQGSCAALSGLTG 1146
LC +L++Y AC A GV + WR + C CP + TCQ +C +LS
Sbjct: 529 LCAALSSYARACTAKGVMLWGWR-EHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADS 587
Query: 1147 CTTRCF---EGCECDDR-FLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSC-- 1200
F +GC C D FL +G C+P+ C C H G YL ++ + ERC C
Sbjct: 588 HCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQE--ERCVCRD 645
Query: 1201 --------------------------------SSSSGLTCQ--AAG-----CPPGRVC-- 1219
S L+CQ AAG C G VC
Sbjct: 646 GRLHCRQIRLIGQSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPD 705
Query: 1220 -----------------------------EVKAEARNCWATRG--LCVLSVGANLTTFDG 1248
++K + C RG +C +V + G
Sbjct: 706 GLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYG 765
Query: 1249 ARGATTSPG-VYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVGQVHIFFQD---GMVT 1304
+ T G Y+ C VA C G+ ++G I ++ G
Sbjct: 766 SGHYITFDGKYYDFDGHC----------SYVAVQDYC-GQNSSLGSFSIITENVPCGTTG 814
Query: 1305 LTPNKGVWVNGLRVDLPAEKLASVSVSRTPDGS-----------LLVRQKAGVQVWLGAN 1353
+T +K + + R +L E V + R L+V G+ V
Sbjct: 815 VTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYTTREVGQYLVVESSTGIIVIWDKR 874
Query: 1354 GKVAVIVSNDHAGKLCGACGNFDGDQTNDW 1383
V + ++ + G +CG CGNFD ND+
Sbjct: 875 TTVFIKLAPSYKGTVCGLCGNFDHRSNNDF 904
Score = 130 bits (326), Expect = 1e-29
Identities = 114/406 (28%), Positives = 169/406 (41%), Gaps = 38/406 (9%)
Query: 57 TCKEQGGQGVCLPNY-EATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLT 115
TC + G+ VC TC ++G HY +FDG+ +DF G C+YV C S+ G
Sbjct: 742 TCTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLG-- 799
Query: 116 PFTVTTKNENRGNPAVSYVRVVTVAALGTNISIH-KDEIGKVRVNGVLTALPVSVADGRI 174
F++ T+N G V+ + + + T + + K + R G A G+
Sbjct: 800 SFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYTTREV-GQY 858
Query: 175 SVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGT 234
V + ++ G+ V +D V + L SY G VCGLCGN D NND +
Sbjct: 859 LVVESST--------GIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHM 910
Query: 235 LAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTC 294
+ S +G SW+ P C D P C + + C L F+ C
Sbjct: 911 VVSSELDFGNSWKEA---PTCPDVSTNPEP-CSLNPHRRSWAEKQCSILKSSV---FSIC 963
Query: 295 HAHVPPESFFKGCVLDVCM--GGGDHDILCKALASYVAACQAAGVVIEDWRAQVGCEITC 352
H+ V P+ F++ CV D C GGD + C A+ASY C G + WR C I C
Sbjct: 964 HSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACV-FWRTPDLCPIFC 1022
Query: 353 PENS-------HYEVCGPPCPASCPSPAPL---TTPAVCEGPCVEGCQCDAG-FVLSADR 401
+ HYE CG +C + + + + EG C C D + +
Sbjct: 1023 DYYNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEG-CYPRCPKDRPIYEEDLKK 1081
Query: 402 CVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTP 447
CV + CGC+ T++ G+ + TC C C +VC P
Sbjct: 1082 CVTADK-CGCYVEDTHYPPGASVPTEETCKS-CVC-TNSSQVVCRP 1124
Score = 127 bits (319), Expect = 8e-29
Identities = 122/451 (27%), Positives = 172/451 (38%), Gaps = 56/451 (12%)
Query: 54 PQETCKEQGGQGVCLPNYEATCWLW---------GDPHYHSFDGRKFDFQGTCNYVLATT 104
P TC G Q V + + + CW W GDPHY +FDG + +QG C YVL
Sbjct: 1912 PMPTCSN-GLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEE 1970
Query: 105 GCLGVSTQGLTPFTV-TTKNENRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLT 163
V G+ N+ P VR T L + + ++ +V+VN
Sbjct: 1971 ISPSVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQV-QVQVNRQAV 2029
Query: 164 ALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYH---GAVCGLCGNM 220
ALP G G + + + + G+ VSY+ V LP YH G CG
Sbjct: 2030 ALPYK-KYGLEVYQSGINYVVDIPELGVLVSYN-GLSFSVRLP--YHRFGNNTKGQCGTC 2085
Query: 221 DRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCP---TCPEDRLEQYEGP 277
++D + P+G + + W L D + CP + + G
Sbjct: 2086 TNTTSDDCILPSGEIVSNCEAAADQW-------LVNDPSKPHCPHSSSTTKRPAVTVPGG 2138
Query: 278 GFCGPLAPGTGGP---------FTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASY 328
G P T P F CHA VPP+ ++ CV D C G + C +L +Y
Sbjct: 2139 GKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSCFMPGS-SLECASLQAY 2197
Query: 329 VAACQAAGVVIEDWRAQV--GCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCV 386
A C + + DWR C + CP + Y+ CGP +C S + V V
Sbjct: 2198 AALCAQQNICL-DWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQNNTV----LV 2252
Query: 387 EGCQCDAG---FVLSADRCVPLNNGCGC-WANGTYHEAGSEFWADGTCSQWCRCGPGGGS 442
EGC C G + D CV CGC + E G F D C C C GG
Sbjct: 2253 EGCFCPEGTMNYAPGFDVCV---KTCGCVGPDNVPREFGEHFEFD--CKN-CVCLEGGSG 2306
Query: 443 LVCTPASCGLGEVCGLLPSGQHGCQPVSTAE 473
++C P C V + G + V+ A+
Sbjct: 2307 IICQPKRCSQKPVTHCVEDGTYLATEVNPAD 2337
Score = 127 bits (318), Expect = 1e-28
Identities = 114/425 (26%), Positives = 167/425 (39%), Gaps = 42/425 (9%)
Query: 816 RCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCG-RCLANGGIHYITLDGRVYDL 874
+ EC P TC G + R+ED C C C G HY+T DG Y
Sbjct: 1905 KVECEPPPMPTCSNGL-----QPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSY 1959
Query: 875 HGSCSYVLAQVCHPKPGDEDFSIVLEK-----NAAGDLQRLLV-------TVAGQVVSLA 922
G+C+YVL + P ++F + ++ N R L+ + V +
Sbjct: 1960 QGNCTYVLVE--EISPSVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMP 2017
Query: 923 QGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTK-GLRLLFDGDAHLLMSIPSP---F 978
QV V+ +AVALP + V G N V+ + G+ + ++G L S+ P F
Sbjct: 2018 MQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVLVSYNG---LSFSVRLPYHRF 2074
Query: 979 RGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSK-GCGEGCGPQGCPVCL 1037
G CG SDD +LP+G S+ E W V SK C P
Sbjct: 2075 GNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVT 2134
Query: 1038 AE---ETAPYES---NEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLC 1091
+T P++ + C +++ FA C A++ P Y+ CV+D C G + C
Sbjct: 2135 VPGGGKTTPHKDCTPSPLCQLIKD--SLFAQCHALVPPQHYYDACVFDSCFMPG-SSLEC 2191
Query: 1092 RSLAAYTAACQAAGVAVKPWR--TDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTT 1149
SL AY A C + + WR T C + CP+H Y C + +C + S T
Sbjct: 2192 ASLQAYAALCAQQNICL-DWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQN-NT 2249
Query: 1150 RCFEGCECDDRFL-LSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTC 1208
EGC C + + + G + V+ CGC DC SG+ C
Sbjct: 2250 VLVEGCFCPEGTMNYAPGFDVCVKTCGCVGPDNVPREFGEHFEFDCKNCVCLEGGSGIIC 2309
Query: 1209 QAAGC 1213
Q C
Sbjct: 2310 QPKRC 2314
Score = 117 bits (294), Expect = 6e-26
Identities = 119/428 (27%), Positives = 183/428 (42%), Gaps = 56/428 (13%)
Query: 459 LPSGQHGCQPVSTAE-------------CQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCH 505
+P+ +G QPV + C WGDPHYVT DG + +QG C Y+L
Sbjct: 1913 MPTCSNGLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEIS 1972
Query: 506 GPPLGAENFTVTVANEH-RGSQAVSYTRSVTLQIYNHSLTLSA----RWPRKLQVDGVFV 560
+NF V + N H + VS R++ ++ + + ++QV+ V
Sbjct: 1973 P---SVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAV 2029
Query: 561 ALPFQLDSLLHAHLSGADVVVTTTS-GLSLAFDGDSFVRLRVP-AAYAASLCGLCGNYNQ 618
ALP++ L + SG + VV G+ ++++G SF +R+P + + G CG
Sbjct: 2030 ALPYKKYG-LEVYQSGINYVVDIPELGVLVSYNGLSF-SVRLPYHRFGNNTKGQCGTCTN 2087
Query: 619 DPADDLKAVGGK-PAGWQVGGAQGCGECVSKP-CPSPCTPEQQESF---GGPDACGVISA 673
+DD G+ + + Q SKP CP + ++ + GG
Sbjct: 2088 TTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDC 2147
Query: 674 TDGPL---------APCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGA 724
T PL A CH LVPP Y+ C+ D+C + G C ++ Y A C
Sbjct: 2148 TPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSCFMPG-SSLECASLQAYAALCAQQNI 2206
Query: 725 QLGEWRRPDF--CPLQCPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAG---F 779
L +WR C ++CP+H Y+ CG + +C S S+ + + EGC C G +
Sbjct: 2207 CL-DWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQN-NTVLVEGCFCPEGTMNY 2264
Query: 780 VLSGDTCVPVGQCGCL-HDGRYYPLGEVFYPGPECERRCECGPGGH-VTCQ-EGAACGPH 836
D CV CGC+ D GE F +C + C C GG + CQ + + P
Sbjct: 2265 APGFDVCVKT--CGCVGPDNVPREFGEHF--EFDC-KNCVCLEGGSGIICQPKRCSQKPV 2319
Query: 837 EECRLEDG 844
C +EDG
Sbjct: 2320 THC-VEDG 2326
Score = 104 bits (259), Expect = 7e-22
Identities = 84/319 (26%), Positives = 129/319 (40%), Gaps = 30/319 (9%)
Query: 474 CQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRS 533
C WG+ HY T DG F F G C+Y ++ C G + F V + ++A + S
Sbjct: 37 CSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRG---SYKEFAVHLKRGPGQAEAPAGVES 93
Query: 534 VTLQIYNHSLTLSARWPRKLQV-DGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFD 592
+ L I + ++ L+ R L V +G V+ P LL S A V + +GL+L ++
Sbjct: 94 ILLTIKDDTIYLT----RHLAVLNGAVVSTPHYSPGLL-IEKSDAYTKVYSRAGLTLMWN 148
Query: 593 GDSFVRLRVPAAYAASLCGLCGNYNQ-DPADDLKAVGGKPAGWQVGGAQG-------CGE 644
+ + L + + CGLCG+YN + + G + + G Q C +
Sbjct: 149 REDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLEFGNMQKINQPDVVCED 208
Query: 645 CVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGH 704
+ P+ C+ + E C + + A C LVP Y + C D C+ G
Sbjct: 209 PEEEVAPASCSEHRAE-------CERLLTAEA-FADCQDLVPLEPYLRACQQDRCRCPGG 260
Query: 705 PGGLCPAVATYVAACQAAGAQLGEWRRPDF-----CPLQCPAHSHYELCGDSCPVSCPSL 759
+C VA + C AG + G WR CP + Y G C +C L
Sbjct: 261 DTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTCSHL 320
Query: 760 SAPEGCESACREGCVCDAG 778
CE +GC C G
Sbjct: 321 EVSSLCEEHRMDGCFCPEG 339
Score = 102 bits (254), Expect = 3e-21
Identities = 109/392 (27%), Positives = 157/392 (40%), Gaps = 39/392 (9%)
Query: 136 VVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVA---DFGLQ 192
VV +A N+ + K + G V +N + LP A SV + +S ++V+ LQ
Sbjct: 348 VVLLADKKKNVVVFKSD-GSVLLNELQVNLPHVTAS--FSVFRPSSYHIMVSMAIGVRLQ 404
Query: 193 VSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWD 252
V ++ VTL + G V GLCGN + +D +G + + + +W+A
Sbjct: 405 VQLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQS-- 462
Query: 253 PLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVC 312
C D+ C + +C L T PF CH+ V P ++K C D C
Sbjct: 463 -SCHDKLDWLDDPCSLNIESANYAEHWCS-LLKKTETPFGRCHSAVDPAEYYKRCKYDTC 520
Query: 313 MGGGDHDILCKALASYVAACQAAGVVIEDWRAQVGCEI---TCPENSHYEVCGPPCPASC 369
+ D LC AL+SY AC A GV++ WR V C +CP + + C +C
Sbjct: 521 NCQNNEDCLCAALSSYARACTAKGVMLWGWREHV-CNKDVGSCPNSQVFLYNLTTCQQTC 579
Query: 370 PSPAPLTTPAVCEGPCVEGCQC-DAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADG 428
S + + + V+GC C D F+ RCVPL C C+ G Y EAG D
Sbjct: 580 RSLSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAK-CSCYHRGLYLEAG-----DV 633
Query: 429 TCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVS--------TAECQAWGDP 480
Q RC G L C +G+ C P C ++ CQ
Sbjct: 634 VVRQEERCVCRDGRLHCRQIRL-IGQSC-TAPKIHMDCSNLTALATSKPRALSCQTLAAG 691
Query: 481 HY--------VTLDGHRFDFQGTCEYLLSAPC 504
+Y V DG D +G C PC
Sbjct: 692 YYHTECVSGCVCPDGLMDDGRGGCVVEKECPC 723
Score = 99.8 bits (247), Expect = 2e-20
Identities = 80/317 (25%), Positives = 135/317 (42%), Gaps = 28/317 (8%)
Query: 856 CLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKN-----AAGDLQRL 910
C G HY T DG V+ G C Y A C + ++F++ L++ A ++ +
Sbjct: 37 CSTWGNFHYKTFDGDVFRFPGLCDYNFASDC--RGSYKEFAVHLKRGPGQAEAPAGVESI 94
Query: 911 LVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHL 970
L+T+ + L + V ++G V+ P + + + + GL L+++ + L
Sbjct: 95 LLTIKDDTIYLTRHLAV-LNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLTLMWNREDAL 153
Query: 971 LMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEGCGP 1030
++ + + FR CGLCG++NG S L +G S +E FG ++ C + P
Sbjct: 154 MLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLE-FGNMQKINQPDVVCED---P 209
Query: 1031 QGCPVCLAEETAPYESNE---ACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDK 1087
+ EE AP +E C +L + FA CQ ++ Y R C D C G
Sbjct: 210 E-------EEVAPASCSEHRAECERLLTAEA-FADCQDLVPLEPYLRACQQDRCRCPGGD 261
Query: 1088 AFLCRSLAAYTAACQAAGVAVKPWRTDSF-----CPLHCPAHSHYSICTRTCQGSCAALS 1142
+C ++A ++ C AG WRT + CP + Y C +C+ L
Sbjct: 262 TCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTCSHLE 321
Query: 1143 GLTGCTTRCFEGCECDD 1159
+ C +GC C +
Sbjct: 322 VSSLCEEHRMDGCFCPE 338
Score = 87.0 bits (214), Expect = 1e-16
Identities = 84/328 (25%), Positives = 127/328 (38%), Gaps = 33/328 (10%)
Query: 75 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLTPFTVTTKNENRGNPAVSYV 134
C WG+ HY +FDG F F G C+Y A + C G F V K A + V
Sbjct: 37 CSTWGNFHYKTFDGDVFRFPGLCDYNFA-SDCRG----SYKEFAVHLKRGPGQAEAPAGV 91
Query: 135 RVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVA--DGRISVAQGASKALLVADFGLQ 192
+ ++I D I R VL VS + + + + + + GL
Sbjct: 92 ESIL-------LTIKDDTIYLTRHLAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLT 144
Query: 193 VSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWD 252
+ ++ + + L + + CGLCG+ + + + +G L + +G + D
Sbjct: 145 LMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLE-FGNMQKINQPD 203
Query: 253 PLCWDECRGSCP-TCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV 311
+C D P +C E R E C L T F C VP E + + C D
Sbjct: 204 VVCEDPEEEVAPASCSEHRAE-------CERLL--TAEAFADCQDLVPLEPYLRACQQDR 254
Query: 312 CMGGGDHDILCKALASYVAACQAAGVVIEDWRAQV-----GCEITCPENSHYEVCGPPCP 366
C G +C +A + C AG +WR G TCP N Y G PC
Sbjct: 255 CRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCM 314
Query: 367 ASCPSPAPLTTPAVCEGPCVEGCQCDAG 394
+C + L ++CE ++GC C G
Sbjct: 315 DTC---SHLEVSSLCEEHRMDGCFCPEG 339
Score = 36.6 bits (83), Expect = 0.17
Identities = 30/92 (32%), Positives = 47/92 (51%), Gaps = 11/92 (11%)
Query: 1294 VHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQVWLGAN 1353
V +F DG V L N L+V+LP AS SV R ++V GV++ +
Sbjct: 358 VVVFKSDGSVLL--------NELQVNLP-HVTASFSVFRPSSYHIMVSMAIGVRLQVQLA 408
Query: 1354 GKVAVIVSNDHA--GKLCGACGNFDGDQTNDW 1383
+ + V+ D A G++ G CGNF+G + +D+
Sbjct: 409 PVMQLFVTLDQASQGQVQGLCGNFNGLEGDDF 440
>gi|37693519 BMP-binding endothelial regulator precursor protein
[Homo sapiens]
Length = 685
Score = 185 bits (469), Expect = 3e-46
Identities = 132/448 (29%), Positives = 191/448 (42%), Gaps = 43/448 (9%)
Query: 368 SCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRC---VPLNNGCGCWANGTYHEAGSEF 424
+C + + VC+ C CD G + C VP + C + G E
Sbjct: 255 NCTACTCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVPPEDIKVCKFGNKIFQDG-EM 313
Query: 425 WADGTCSQWCRCGPGGGSL---VCTP-ASCGLGEVCGLLPSGQHGCQPVSTAE---CQAW 477
W+ C+ C C G C P +SC G++ + GC P+ T + C +
Sbjct: 314 WSSINCTI-CACVKGRTECRNKQCIPISSCPQGKILN-----RKGCCPICTEKPGVCTVF 367
Query: 478 GDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQ 537
GDPHY T DG F+FQGTC+Y+L+ C P A F V V N+ R +++ S+T+SV L
Sbjct: 368 GDPHYNTFDGRTFNFQGTCQYVLTKDCSSP---ASPFQVLVKNDARRTRSFSWTKSVELV 424
Query: 538 IYNHSLTL----SARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDG 593
+ ++L + RW +G +ALP + H L G + VTT +GL +++DG
Sbjct: 425 LGESRVSLQQHLTVRW------NGSRIALPCRAPHF-HIDLDGYLLKVTTKAGLEISWDG 477
Query: 594 DSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGK--------PAGWQVGGAQGCGEC 645
DSFV + LCGLCGNYN DDL G W+V + C
Sbjct: 478 DSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCNRP 537
Query: 646 VSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHP 705
KP P C + C + + + CH V A +++ C+ D C+ H
Sbjct: 538 QRKPVPELCQGTVKVKLRAHRECQKLKSWE--FQTCHSTVDYATFYRSCVTDMCECPVHK 595
Query: 706 GGLCPAVATYVAACQAAGAQLGEWRRPDFCPL-QCPAHSHYELCGDSCPVSCPSLSAPEG 764
C + Y ACQ G ++ W C QC + Y+ CG C +C + +
Sbjct: 596 NCYCESFLAYTRACQREGIKV-HWEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGP 654
Query: 765 CESACREGCVCDAGFVLSGDTCVPVGQC 792
C C GC C A VL C+ C
Sbjct: 655 CNKPCVAGCHCPANLVLHKGRCIKPVLC 682
Score = 157 bits (396), Expect = 9e-38
Identities = 109/364 (29%), Positives = 163/364 (44%), Gaps = 24/364 (6%)
Query: 47 CHGVTCRPQETC---KEQGGQGVC--LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVL 101
C C P +C K +G C C ++GDPHY++FDGR F+FQGTC YVL
Sbjct: 331 CRNKQCIPISSCPQGKILNRKGCCPICTEKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVL 390
Query: 102 ATTGCLGVSTQGLTPFTVTTKNENRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGV 161
T C + +PF V KN+ R + S+ + V + + +S+ + VR NG
Sbjct: 391 -TKDC----SSPASPFQVLVKNDARRTRSFSWTKSVELVLGESRVSLQQHLT--VRWNGS 443
Query: 162 LTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMD 221
ALP I + K A GL++S+D + V+V G +CGLCGN +
Sbjct: 444 RIALPCRAPHFHIDLDGYLLKVTTKA--GLEISWDGDSFVEVMAAPHLKGKLCGLCGNYN 501
Query: 222 RNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLE-QYEGPGFC 280
+ +D + +G + + SWR + C R P + ++ + C
Sbjct: 502 GHKRDDLIGGDGNFKFDVDDFAESWRVES-NEFCNRPQRKPVPELCQGTVKVKLRAHREC 560
Query: 281 GPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVVIE 340
L F TCH+ V +F++ CV D+C + C++ +Y ACQ G+ +
Sbjct: 561 QKLK---SWEFQTCHSTVDYATFYRSCVTDMCECPVHKNCYCESFLAYTRACQREGIKVH 617
Query: 341 DWRAQVGCEIT-CPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSA 399
W Q C T C + Y+ CGP C +C + + C PCV GC C A VL
Sbjct: 618 -WEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEI---GPCNKPCVAGCHCPANLVLHK 673
Query: 400 DRCV 403
RC+
Sbjct: 674 GRCI 677
Score = 155 bits (391), Expect = 3e-37
Identities = 125/440 (28%), Positives = 186/440 (42%), Gaps = 41/440 (9%)
Query: 748 CGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVF 807
C DS V S P GC+ +EGC C+ + + V C + + GE+
Sbjct: 261 CRDSTVVCKRKCSHPGGCDQG-QEGC-CEECLLRVPPEDIKV----CKFGNKIFQDGEM- 313
Query: 808 YPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGC--------GRCLAN 859
+ C C C G C+ C P C + + GC G C
Sbjct: 314 WSSINCTI-CACVKG-RTECRN-KQCIPISSCPQG---KILNRKGCCPICTEKPGVCTVF 367
Query: 860 GGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVV 919
G HY T DGR ++ G+C YVL + C VL KN A + T + ++V
Sbjct: 368 GDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQ---VLVKNDARRTRSFSWTKSVELV 424
Query: 920 ------SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMS 973
SL Q V +G +ALP + +G + + T GL + +DGD+ + +
Sbjct: 425 LGESRVSLQQHLTVRWNGSRIALPCRAPHFHIDLDGYLLKVTTKAGLEISWDGDSFVEVM 484
Query: 974 IPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEGCGPQGC 1033
+G+LCGLCGN+NG+ DD + +G+ V+ F +WRV S++ C PQ
Sbjct: 485 AAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVE-SNEFCNR---PQRK 540
Query: 1034 PV---CLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFL 1090
PV C ++ C +L++ + F TC + + + ++R CV D+C K
Sbjct: 541 PVPELCQGTVKVKLRAHRECQKLKSWE--FQTCHSTVDYATFYRSCVTDMCECPVHKNCY 598
Query: 1091 CRSLAAYTAACQAAGVAVKPWRTDSFC-PLHCPAHSHYSICTRTCQGSCAALSGLTGCTT 1149
C S AYT ACQ G+ V W C C + Y C C +C + + C
Sbjct: 599 CESFLAYTRACQREGIKVH-WEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGPCNK 657
Query: 1150 RCFEGCECDDRFLLSQGVCI 1169
C GC C +L +G CI
Sbjct: 658 PCVAGCHCPANLVLHKGRCI 677
Score = 56.6 bits (135), Expect = 2e-07
Identities = 60/268 (22%), Positives = 96/268 (35%), Gaps = 25/268 (9%)
Query: 1121 CPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQDCGCTHNG 1180
C +C R C G GC C + +P +D G
Sbjct: 259 CTCRDSTVVCKRKCSHPGGCDQGQEGCCEECL--------------LRVPPEDIKVCKFG 304
Query: 1181 RYLPVNSSLLTSDCSERCSC----SSSSGLTC-QAAGCPPGRVCEVKAEARNCWATRGLC 1235
+ + + +S C+C + C + CP G++ K C G+C
Sbjct: 305 NKIFQDGEMWSSINCTICACVKGRTECRNKQCIPISSCPQGKILNRKGCCPICTEKPGVC 364
Query: 1236 VLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVGQVH 1295
+ + TFDG Y L+ C + P+ +V V
Sbjct: 365 TVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPAS--PFQVLVKNDARRTRSFSWTKSVE 422
Query: 1296 IFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDGSLL-VRQKAGVQVWLGANG 1354
+ + V+L + V NG R+ LP + DG LL V KAG+++ +
Sbjct: 423 LVLGESRVSLQQHLTVRWNGSRIALPCR---APHFHIDLDGYLLKVTTKAGLEISWDGDS 479
Query: 1355 KVAVIVSNDHAGKLCGACGNFDGDQTND 1382
V V+ + GKLCG CGN++G + +D
Sbjct: 480 FVEVMAAPHLKGKLCGLCGNYNGHKRDD 507
Score = 31.6 bits (70), Expect = 5.6
Identities = 32/94 (34%), Positives = 40/94 (42%), Gaps = 22/94 (23%)
Query: 384 PCVEGCQCDAGFVL-SADRCV-----PLNN------GC-GCWANGTYHEAGSEFWADGTC 430
PCV QC G V S RCV PL + C GC G ++ G EF +G
Sbjct: 127 PCVLR-QCQEGVVTESGVRCVVHCKNPLEHLGMCCPTCPGCVFEGVQYQEGEEFQPEG-- 183
Query: 431 SQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQH 464
S+ +C GG C + EVC +L QH
Sbjct: 184 SKCTKCSCTGGRTQC------VREVCPILSCPQH 211
Score = 31.6 bits (70), Expect = 5.6
Identities = 23/68 (33%), Positives = 32/68 (47%), Gaps = 11/68 (16%)
Query: 769 CREGCVCDAGF---VLSGDTCVPVGQC-----GCLHDGRYYPLGEVFYP-GPECERRCEC 819
C+EG V ++G V + +G C GC+ +G Y GE F P G +C +C C
Sbjct: 133 CQEGVVTESGVRCVVHCKNPLEHLGMCCPTCPGCVFEGVQYQEGEEFQPEGSKC-TKCSC 191
Query: 820 GPGGHVTC 827
GG C
Sbjct: 192 -TGGRTQC 198
>gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo
sapiens]
Length = 2134
Score = 144 bits (363), Expect = 6e-34
Identities = 139/532 (26%), Positives = 207/532 (38%), Gaps = 89/532 (16%)
Query: 769 CREGCVCDAGFVL-SGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTC 827
C+ GC C G V S CV C C GR Y G V G C EC TC
Sbjct: 1253 CKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYDEGSVTSVG--CN---EC------TC 1301
Query: 828 QEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCSY-VLAQVC 886
+G+ EC+ CH G G H T DG+ Y G C Y L C
Sbjct: 1302 IKGSWSCTQNECQT-----ICHIYGEG--------HVRTFDGKSYSFDGLCQYSFLEDYC 1348
Query: 887 HPKPGDEDFSIVLE-----KNAAGDLQRLLVTVAGQVVSLAQGQQVTVDG-EAVALPVAV 940
+ G F I+ E ++ ++++V Q + L G+ V E+ +
Sbjct: 1349 GHENGT--FRILTESVPCCEDGLTCSRKIIVAFQDQNIVLQDGKVTAVKSTESKKCELNA 1406
Query: 941 GRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLP 1000
+ G ++L+ G+ +++D + L + + + G++CGLCGN NG+ DDF
Sbjct: 1407 NAYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTR 1466
Query: 1001 NGSAASSVETFGAAWRVPGSSKGCGEGCGPQGCPVCLAEETAPYESN--------EACGQ 1052
S AS FG +W+ +S+ C + +T P +SN C
Sbjct: 1467 YSSVASGALEFGNSWK---TSQECSD----------TVAQTFPCDSNPYCKAWAVRKCEI 1513
Query: 1053 LRNPQGPFATCQAVLSPSEYFRQCVYDLCA--QKGDKAFLCRSLAAYTAACQAAGVAVKP 1110
LR+ F C + PS Y C+ + CA +G C ++A Y AC A GV V
Sbjct: 1514 LRD--STFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCVS- 1570
Query: 1111 WRTDSFCPLHCPAHS-------HYSIC----TRTCQGSCAA---LSGLTGCTTRCFEGCE 1156
WR + CP++C ++ HY C +TC+ S L GC +C +
Sbjct: 1571 WRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQKFSSLLEGCYAKCPDSAP 1630
Query: 1157 CDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPG 1216
D + C+ + +C C +N +P ++ +C C C + L C P
Sbjct: 1631 YLDENTMK---CVSLSECSCFYND-VIPA-GGVIEDNCGRTCYCIAGQ-LECSET-APTN 1683
Query: 1217 RVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTS-PGVYELSSRCPG 1267
V T +LS GA +T G S P + SS G
Sbjct: 1684 STFAVS-------TTTATTILSTGAAITLVTGGPSTAASIPAITTSSSETTG 1728
Score = 135 bits (340), Expect = 3e-31
Identities = 153/599 (25%), Positives = 222/599 (37%), Gaps = 102/599 (17%)
Query: 261 GSCPTCPEDRLEQYE-GPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHD 319
G CP E E G C + G F C + +K +D D
Sbjct: 669 GDCPNAVGKSYEVCEDGIQHCNKII---GTYFEKCGKVAALSNDYKMICIDEYCQTRDKT 725
Query: 320 ILCKALASYVAACQAAGV-VIEDWRAQ--VGCEIT-CPENSHYEVCGPPCPASCPSPAPL 375
C + C + G E WR+ V CE CPE Y+ CGP PA+C + AP
Sbjct: 726 STCDTYSELSRLCASDGPGTFESWRSDSDVVCETQRCPEQHIYKECGPSNPATCSNVAPF 785
Query: 376 TTPAVCEGPCVEGCQCDAGFVLS----ADRCVPLNNGCGCWANGTYHEAGSEFWADGTCS 431
+ CV GC C G++L +CV L C C ++GT ++ G +G C
Sbjct: 786 Q-----DSECVSGCTCPEGYLLDDIGEKGKCV-LKAECPCESSGTVYQPGEV--REGPCG 837
Query: 432 QWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFD 491
C C S CT A C C+ G T DG +++
Sbjct: 838 SQCTCQDAKWS--CTEALC--------------------PGRCKVEGSS-LTTFDGVKYN 874
Query: 492 FQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGS-QAVSYTRSVTL----------QIYN 540
F G C +L + E+++++V S Q + SVTL ++N
Sbjct: 875 FPGNCHFLA--------VHNEDWSISVELRPCPSGQTGTCLNSVTLLLNSSVPVDKYVFN 926
Query: 541 HSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLR 600
T++ K++ G + + Q+ + ++L V T + L ++L
Sbjct: 927 SDGTVTND---KIRNQGYYYSDKIQIFNASSSYLQ-----VETYFHVKLQIQIVPVMQLY 978
Query: 601 V--PAAYAASLCGLCGNYNQDPADDL--------KAVGGKPAGWQVGGAQGCGECVSKPC 650
V P GLCG+YN DD K W++ C K
Sbjct: 979 VSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEM---MSC----PKGN 1031
Query: 651 PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCP 710
PS C ++E F CG++ + GPLA CH +V P Y + C C + LC
Sbjct: 1032 PSSCISIEKEKFAERH-CGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCT 1090
Query: 711 AVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPE---GCES 767
+ YV AC + W R C CP+ ++ +C SC SLS + E
Sbjct: 1091 ILGNYVKACAEKETYIVGW-RTGLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVED 1149
Query: 768 ACREGCVC-DAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPEC---ERRCECGPG 822
+GC C DA + + CV QC C Y EV PG + +C C G
Sbjct: 1150 VPVDGCTCPDAMYQNNEGNCVLKSQCDC------YINDEVMQPGKLIHIDDNKCVCRDG 1202
Score = 127 bits (319), Expect = 8e-29
Identities = 124/482 (25%), Positives = 191/482 (39%), Gaps = 87/482 (18%)
Query: 384 PCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSL 443
PC GC C G V ++ N C C G ++ GS C++ C C G S
Sbjct: 1252 PCKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYDEGSV--TSVGCNE-CTCIKGSWS- 1307
Query: 444 VCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEY-LLSA 502
CT Q+ CQ + C +G+ H T DG + F G C+Y L
Sbjct: 1308 -CT----------------QNECQTI----CHIYGEGHVRTFDGKSYSFDGLCQYSFLED 1346
Query: 503 PCHGPPLGAENFTVTVANEHRG--SQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFV 560
C G EN T + E ++ +R + + + ++ L DG
Sbjct: 1347 YC-----GHENGTFRILTESVPCCEDGLTCSRKIIVAFQDQNIVLQ---------DGKVT 1392
Query: 561 ALPF------QLDSLLHA-HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLC 613
A+ +L++ ++ H G +++ +G+ + +D ++ + + + + +CGLC
Sbjct: 1393 AVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLC 1452
Query: 614 GNYNQDPADDLK------AVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDA 667
GN N D DD A G G +Q C + V++ PC
Sbjct: 1453 GNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQ--TFPCDSNPYCKAWAVRK 1510
Query: 668 CGVISATDGPLAPCHGLVPPAQYFQGCLLD--ACQVQGHPGGLCPAVATYVAACQAAGAQ 725
C ++ D CH V P+ Y C+ + AC ++G G C AVA Y AC A G
Sbjct: 1511 CEIL--RDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVC 1568
Query: 726 LGEWRRPDFCPLQCPAHS-------HYELCGDSCPVSCPS-------LSAPEGCESACRE 771
+ WR+P+ CP+ C ++ HYE CG +C S EGC + C
Sbjct: 1569 V-SWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQKFSSLLEGCYAKCP- 1626
Query: 772 GCVCDAGFVLSGDT--CVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQE 829
D+ L +T CV + +C C ++ P G V C R C C G + C E
Sbjct: 1627 ----DSAPYLDENTMKCVSLSECSCFYND-VIPAGGVI--EDNCGRTCYC-IAGQLECSE 1678
Query: 830 GA 831
A
Sbjct: 1679 TA 1680
Score = 127 bits (318), Expect = 1e-28
Identities = 131/545 (24%), Positives = 194/545 (35%), Gaps = 80/545 (14%)
Query: 694 CLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPD---FCPLQ-CPAHSHYELCG 749
C+ + CQ + C + C + G E R D C Q CP Y+ CG
Sbjct: 714 CIDEYCQTRDKTS-TCDTYSELSRLCASDGPGTFESWRSDSDVVCETQRCPEQHIYKECG 772
Query: 750 DSCPVSCPSLSAPEGCESACREGCVCDAGFVLSG----DTCVPVGQCGCLHDGRYYPLGE 805
S P +C +++ + +S C GC C G++L CV +C C G Y GE
Sbjct: 773 PSNPATCSNVAPFQ--DSECVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGE 830
Query: 806 VFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGC-GRCLANGGIHY 864
V R CG +C +D +C C GRC G
Sbjct: 831 V--------REGPCG----------------SQCTCQDAKWSCTEALCPGRCKVEGS-SL 865
Query: 865 ITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVSLAQG 924
T DG Y+ G+C ++ +ED+SI +E Q V+L
Sbjct: 866 TTFDGVKYNFPGNCHFLAVH-------NEDWSISVELRPCPSGQ---TGTCLNSVTLLLN 915
Query: 925 QQVTVDGEAVALPVAVGRVRVTAEG------------RNMVLQTTK----GLRLLFDGDA 968
V VD V ++ +G + LQ L++
Sbjct: 916 SSVPVDKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASSSYLQVETYFHVKLQIQIVPVM 975
Query: 969 HLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEGC 1028
L +S+P GLCG++N DDF+ + + F +W + KG
Sbjct: 976 QLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMSCPKG----- 1030
Query: 1029 GPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKA 1088
P C E+ A CG L + GP A+C +++P Y +C C + +
Sbjct: 1031 NPSSCISIEKEKFA----ERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQD 1086
Query: 1089 FLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGL-TGC 1147
LC L Y AC + WRT C CP+ + + C SC +LS C
Sbjct: 1087 CLCTILGNYVKACAEKETYIVGWRT-GLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSC 1145
Query: 1148 TTR--CFEGCECDD-RFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSS 1204
+GC C D + ++G C+ C C N + + D +C C
Sbjct: 1146 DVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDD--NKCVCRDGI 1203
Query: 1205 GLTCQ 1209
L CQ
Sbjct: 1204 -LLCQ 1207
Score = 96.3 bits (238), Expect = 2e-19
Identities = 96/389 (24%), Positives = 151/389 (38%), Gaps = 32/389 (8%)
Query: 63 GQGVCLPNY-EATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLTPFTVTT 121
G C N + C ++G+ H +FDG+ + F G C Y C + F + T
Sbjct: 1304 GSWSCTQNECQTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHENGT----FRILT 1359
Query: 122 KNENRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGAS 181
++ ++ R + VA NI + GKV + + S+
Sbjct: 1360 ESVPCCEDGLTCSRKIIVAFQDQNIVLQD---GKVTAVKSTESKKCELNANAYSIHTVGL 1416
Query: 182 KALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPI 241
+L G+ V +D N R+ V L +++G VCGLCGN + + +D ++A
Sbjct: 1417 YLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALE 1476
Query: 242 WGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPE 301
+G SW+ C D + P C + + C L T F CH V P
Sbjct: 1477 FGNSWKT---SQECSDTVAQTFP-CDSNPYCKAWAVRKCEILRDST---FRDCHNKVDPS 1529
Query: 302 SFFKGCVLDVCMGG--GDHDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENS--- 356
++ C+ + C G + C A+A Y AC A GV + WR C + C +
Sbjct: 1530 AYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCV-SWRKPNLCPVYCDYYNAPG 1588
Query: 357 ----HYEVCGPPCPASCPSP-APLTTPAVCEGPCVEGCQCDAGFV-LSADRCVPLNNGCG 410
HYE CG +C ++ EG C C A ++ + +CV L+ C
Sbjct: 1589 ECRWHYEPCGTVTAKTCKDQLVGQKFSSLLEG-CYAKCPDSAPYLDENTMKCVSLSE-CS 1646
Query: 411 CWANGTYHEAGSEFWADGTCSQWCRCGPG 439
C+ N G + C + C C G
Sbjct: 1647 CFYNDVIPAGGV---IEDNCGRTCYCIAG 1672
Score = 85.5 bits (210), Expect = 3e-16
Identities = 105/457 (22%), Positives = 172/457 (37%), Gaps = 55/457 (12%)
Query: 5 ECGLACSNPQIPGTDWVDMEGAAMLYNGQPLKVLLPLLSPDPCHGVTCRPQETCKEQGG- 63
EC C+ P+ D + +G +L P + + P C Q TC++
Sbjct: 789 ECVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGEVREGPCGSQCTCQDAKWS 848
Query: 64 --QGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLTPF---- 117
+ +C C + G +FDG K++F G C+++ +S + L P
Sbjct: 849 CTEALC----PGRCKVEGSS-LTTFDGVKYNFPGNCHFLAVHNEDWSISVE-LRPCPSGQ 902
Query: 118 TVTTKNE-----NRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADG 172
T T N N P YV ++ ++ D K+R G +
Sbjct: 903 TGTCLNSVTLLLNSSVPVDKYV-------FNSDGTVTND---KIRNQGYYYS-------D 945
Query: 173 RISVAQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQV 229
+I + +S L V + LQ+ ++ V++P + GLCG+ + +D +
Sbjct: 946 KIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFM 1005
Query: 230 FPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGG 289
L + + SW C SC + +++ + CG L + G
Sbjct: 1006 SSQNILEKTSQAFANSWEMMS----CPKGNPSSCISIEKEKFAERH----CGILL-DSSG 1056
Query: 290 PFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVVIEDWRAQVGCE 349
P +CH V P+ + + C C D LC L +YV AC I WR + CE
Sbjct: 1057 PLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGL-CE 1115
Query: 350 ITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQC-DAGFVLSADRCVPLNNG 408
+CP ++ C +SC S + E V+GC C DA + + CV L +
Sbjct: 1116 HSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCV-LKSQ 1174
Query: 409 CGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVC 445
C C+ N + G D +C G L+C
Sbjct: 1175 CDCYINDEVMQPGKLIHIDDN-----KCVCRDGILLC 1206
Score = 61.6 bits (148), Expect = 5e-09
Identities = 52/200 (26%), Positives = 83/200 (41%), Gaps = 33/200 (16%)
Query: 1060 FATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAV-KPWRTDS--F 1116
F C V + S ++ D Q DK C + + + C + G + WR+DS
Sbjct: 697 FEKCGKVAALSNDYKMICIDEYCQTRDKTSTCDTYSELSRLCASDGPGTFESWRSDSDVV 756
Query: 1117 CPLH-CPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLL----SQGVCIPV 1171
C CP Y C + +C+ ++ + C GC C + +LL +G C+
Sbjct: 757 CETQRCPEQHIYKECGPSNPATCSNVAPFQD--SECVSGCTCPEGYLLDDIGEKGKCVLK 814
Query: 1172 QDCGCTHNGR-YLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWA 1230
+C C +G Y P + C +C+C + +C A C PGR C+V+
Sbjct: 815 AECPCESSGTVYQP--GEVREGPCGSQCTCQDAK-WSCTEALC-PGR-CKVE-------- 861
Query: 1231 TRGLCVLSVGANLTTFDGAR 1250
G++LTTFDG +
Sbjct: 862 ---------GSSLTTFDGVK 872
Score = 60.1 bits (144), Expect = 1e-08
Identities = 58/235 (24%), Positives = 97/235 (41%), Gaps = 26/235 (11%)
Query: 1151 CFEGCECDDRFLL-SQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQ 1209
C GC C + + S+G+C+ DC C+ GR S+ + C+E C+C S +C
Sbjct: 1253 CKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYD-EGSVTSVGCNE-CTCIKGSW-SCT 1309
Query: 1210 AAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQ 1269
C +C + E ++ TFDG + Y G +
Sbjct: 1310 QNECQT--ICHIYGEG----------------HVRTFDGKSYSFDGLCQYSFLEDYCGHE 1351
Query: 1270 NTIPWYRVVAE-VQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASV 1328
N +R++ E V C ++ + FQD + L K V E A+
Sbjct: 1352 NGT--FRILTESVPCCEDGLTCSRKIIVAFQDQNIVLQDGKVTAVKSTE-SKKCELNANA 1408
Query: 1329 SVSRTPDGSLLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTNDW 1383
T L+++ + G+ V N +++VI+ + GK+CG CGN +GD +D+
Sbjct: 1409 YSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDF 1463
>gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo
sapiens]
Length = 2134
Score = 144 bits (363), Expect = 6e-34
Identities = 139/532 (26%), Positives = 207/532 (38%), Gaps = 89/532 (16%)
Query: 769 CREGCVCDAGFVL-SGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTC 827
C+ GC C G V S CV C C GR Y G V G C EC TC
Sbjct: 1253 CKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYDEGSVTSVG--CN---EC------TC 1301
Query: 828 QEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCSY-VLAQVC 886
+G+ EC+ CH G G H T DG+ Y G C Y L C
Sbjct: 1302 IKGSWSCTQNECQT-----ICHIYGEG--------HVRTFDGKSYSFDGLCQYSFLEDYC 1348
Query: 887 HPKPGDEDFSIVLE-----KNAAGDLQRLLVTVAGQVVSLAQGQQVTVDG-EAVALPVAV 940
+ G F I+ E ++ ++++V Q + L G+ V E+ +
Sbjct: 1349 GHENGT--FRILTESVPCCEDGLTCSRKIIVAFQDQNIVLQDGKVTAVKSTESKKCELNA 1406
Query: 941 GRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLP 1000
+ G ++L+ G+ +++D + L + + + G++CGLCGN NG+ DDF
Sbjct: 1407 NAYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTR 1466
Query: 1001 NGSAASSVETFGAAWRVPGSSKGCGEGCGPQGCPVCLAEETAPYESN--------EACGQ 1052
S AS FG +W+ +S+ C + +T P +SN C
Sbjct: 1467 YSSVASGALEFGNSWK---TSQECSD----------TVAQTFPCDSNPYCKAWAVRKCEI 1513
Query: 1053 LRNPQGPFATCQAVLSPSEYFRQCVYDLCA--QKGDKAFLCRSLAAYTAACQAAGVAVKP 1110
LR+ F C + PS Y C+ + CA +G C ++A Y AC A GV V
Sbjct: 1514 LRD--STFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCVS- 1570
Query: 1111 WRTDSFCPLHCPAHS-------HYSIC----TRTCQGSCAA---LSGLTGCTTRCFEGCE 1156
WR + CP++C ++ HY C +TC+ S L GC +C +
Sbjct: 1571 WRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQKFSSLLEGCYAKCPDSAP 1630
Query: 1157 CDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPG 1216
D + C+ + +C C +N +P ++ +C C C + L C P
Sbjct: 1631 YLDENTMK---CVSLSECSCFYND-VIPA-GGVIEDNCGRTCYCIAGQ-LECSET-APTN 1683
Query: 1217 RVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTS-PGVYELSSRCPG 1267
V T +LS GA +T G S P + SS G
Sbjct: 1684 STFAVS-------TTTATTILSTGAAITLVTGGPSTAASIPAITTSSSETTG 1728
Score = 132 bits (333), Expect = 2e-30
Identities = 152/599 (25%), Positives = 221/599 (36%), Gaps = 102/599 (17%)
Query: 261 GSCPTCPEDRLEQYE-GPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHD 319
G CP E E G C + G F C + +K +D D
Sbjct: 669 GDCPNAVGKSYEVCEDGIQHCNKII---GTYFEKCGKVAALSNDYKMICIDEYCQTRDKT 725
Query: 320 ILCKALASYVAACQAAGV-VIEDWRAQ--VGCEIT-CPENSHYEVCGPPCPASCPSPAPL 375
C + C + G E WR+ V C CPE Y+ CGP PA+C + AP
Sbjct: 726 STCDTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECGPSNPATCSNVAPF 785
Query: 376 TTPAVCEGPCVEGCQCDAGFVLS----ADRCVPLNNGCGCWANGTYHEAGSEFWADGTCS 431
+ CV GC C G++L +CV L C C ++GT ++ G +G C
Sbjct: 786 Q-----DSECVSGCTCPEGYLLDDIGEKGKCV-LKAECPCESSGTVYQPGEV--REGPCG 837
Query: 432 QWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFD 491
C C S CT A C C+ G T DG +++
Sbjct: 838 SQCTCQDAKWS--CTEALC--------------------PGRCKVEGSS-LTTFDGVKYN 874
Query: 492 FQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGS-QAVSYTRSVTL----------QIYN 540
F G C +L + E+++++V S Q + SVTL ++N
Sbjct: 875 FPGNCHFLA--------VHNEDWSISVELRPCPSGQTGTCLNSVTLLLNSSVPVDKYVFN 926
Query: 541 HSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLR 600
T++ K++ G + + Q+ + ++L V T + L ++L
Sbjct: 927 SDGTVTND---KIRNQGYYYSDKIQIFNASSSYLQ-----VETYFHVKLQIQIVPVMQLY 978
Query: 601 V--PAAYAASLCGLCGNYNQDPADDL--------KAVGGKPAGWQVGGAQGCGECVSKPC 650
V P GLCG+YN DD K W++ C K
Sbjct: 979 VSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEM---MSC----PKGN 1031
Query: 651 PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCP 710
PS C ++E F CG++ + GPLA CH +V P Y + C C + LC
Sbjct: 1032 PSSCISIEKEKFAERH-CGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCT 1090
Query: 711 AVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPE---GCES 767
+ YV AC + W R C CP+ ++ +C SC SLS + E
Sbjct: 1091 ILGNYVKACAEKETYIVGW-RTGLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVED 1149
Query: 768 ACREGCVC-DAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPEC---ERRCECGPG 822
+GC C DA + + CV QC C Y EV PG + +C C G
Sbjct: 1150 VPVDGCTCPDAMYQNNEGNCVLKSQCDC------YINDEVMQPGKLIHIDDNKCVCRDG 1202
Score = 127 bits (319), Expect = 8e-29
Identities = 124/482 (25%), Positives = 191/482 (39%), Gaps = 87/482 (18%)
Query: 384 PCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSL 443
PC GC C G V ++ N C C G ++ GS C++ C C G S
Sbjct: 1252 PCKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYDEGSV--TSVGCNE-CTCIKGSWS- 1307
Query: 444 VCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEY-LLSA 502
CT Q+ CQ + C +G+ H T DG + F G C+Y L
Sbjct: 1308 -CT----------------QNECQTI----CHIYGEGHVRTFDGKSYSFDGLCQYSFLED 1346
Query: 503 PCHGPPLGAENFTVTVANEHRG--SQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFV 560
C G EN T + E ++ +R + + + ++ L DG
Sbjct: 1347 YC-----GHENGTFRILTESVPCCEDGLTCSRKIIVAFQDQNIVLQ---------DGKVT 1392
Query: 561 ALPF------QLDSLLHA-HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLC 613
A+ +L++ ++ H G +++ +G+ + +D ++ + + + + +CGLC
Sbjct: 1393 AVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLC 1452
Query: 614 GNYNQDPADDLK------AVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDA 667
GN N D DD A G G +Q C + V++ PC
Sbjct: 1453 GNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQ--TFPCDSNPYCKAWAVRK 1510
Query: 668 CGVISATDGPLAPCHGLVPPAQYFQGCLLD--ACQVQGHPGGLCPAVATYVAACQAAGAQ 725
C ++ D CH V P+ Y C+ + AC ++G G C AVA Y AC A G
Sbjct: 1511 CEIL--RDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVC 1568
Query: 726 LGEWRRPDFCPLQCPAHS-------HYELCGDSCPVSCPS-------LSAPEGCESACRE 771
+ WR+P+ CP+ C ++ HYE CG +C S EGC + C
Sbjct: 1569 V-SWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQKFSSLLEGCYAKCP- 1626
Query: 772 GCVCDAGFVLSGDT--CVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQE 829
D+ L +T CV + +C C ++ P G V C R C C G + C E
Sbjct: 1627 ----DSAPYLDENTMKCVSLSECSCFYND-VIPAGGVI--EDNCGRTCYC-IAGQLECSE 1678
Query: 830 GA 831
A
Sbjct: 1679 TA 1680
Score = 126 bits (317), Expect = 1e-28
Identities = 131/545 (24%), Positives = 194/545 (35%), Gaps = 80/545 (14%)
Query: 694 CLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPD---FCPLQ-CPAHSHYELCG 749
C+ + CQ + C + C + G E R D C Q CP Y+ CG
Sbjct: 714 CIDEYCQTRDKTS-TCDTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECG 772
Query: 750 DSCPVSCPSLSAPEGCESACREGCVCDAGFVLSG----DTCVPVGQCGCLHDGRYYPLGE 805
S P +C +++ + +S C GC C G++L CV +C C G Y GE
Sbjct: 773 PSNPATCSNVAPFQ--DSECVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGE 830
Query: 806 VFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGC-GRCLANGGIHY 864
V R CG +C +D +C C GRC G
Sbjct: 831 V--------REGPCG----------------SQCTCQDAKWSCTEALCPGRCKVEGS-SL 865
Query: 865 ITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVSLAQG 924
T DG Y+ G+C ++ +ED+SI +E Q V+L
Sbjct: 866 TTFDGVKYNFPGNCHFLAVH-------NEDWSISVELRPCPSGQ---TGTCLNSVTLLLN 915
Query: 925 QQVTVDGEAVALPVAVGRVRVTAEG------------RNMVLQTTK----GLRLLFDGDA 968
V VD V ++ +G + LQ L++
Sbjct: 916 SSVPVDKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASSSYLQVETYFHVKLQIQIVPVM 975
Query: 969 HLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEGC 1028
L +S+P GLCG++N DDF+ + + F +W + KG
Sbjct: 976 QLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMSCPKG----- 1030
Query: 1029 GPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKA 1088
P C E+ A CG L + GP A+C +++P Y +C C + +
Sbjct: 1031 NPSSCISIEKEKFA----ERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQD 1086
Query: 1089 FLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGL-TGC 1147
LC L Y AC + WRT C CP+ + + C SC +LS C
Sbjct: 1087 CLCTILGNYVKACAEKETYIVGWRT-GLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSC 1145
Query: 1148 TTR--CFEGCECDD-RFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSS 1204
+GC C D + ++G C+ C C N + + D +C C
Sbjct: 1146 DVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDD--NKCVCRDGI 1203
Query: 1205 GLTCQ 1209
L CQ
Sbjct: 1204 -LLCQ 1207
Score = 96.3 bits (238), Expect = 2e-19
Identities = 96/389 (24%), Positives = 151/389 (38%), Gaps = 32/389 (8%)
Query: 63 GQGVCLPNY-EATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLTPFTVTT 121
G C N + C ++G+ H +FDG+ + F G C Y C + F + T
Sbjct: 1304 GSWSCTQNECQTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHENGT----FRILT 1359
Query: 122 KNENRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGAS 181
++ ++ R + VA NI + GKV + + S+
Sbjct: 1360 ESVPCCEDGLTCSRKIIVAFQDQNIVLQD---GKVTAVKSTESKKCELNANAYSIHTVGL 1416
Query: 182 KALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPI 241
+L G+ V +D N R+ V L +++G VCGLCGN + + +D ++A
Sbjct: 1417 YLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALE 1476
Query: 242 WGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPE 301
+G SW+ C D + P C + + C L T F CH V P
Sbjct: 1477 FGNSWKT---SQECSDTVAQTFP-CDSNPYCKAWAVRKCEILRDST---FRDCHNKVDPS 1529
Query: 302 SFFKGCVLDVCMGG--GDHDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENS--- 356
++ C+ + C G + C A+A Y AC A GV + WR C + C +
Sbjct: 1530 AYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCV-SWRKPNLCPVYCDYYNAPG 1588
Query: 357 ----HYEVCGPPCPASCPSP-APLTTPAVCEGPCVEGCQCDAGFV-LSADRCVPLNNGCG 410
HYE CG +C ++ EG C C A ++ + +CV L+ C
Sbjct: 1589 ECRWHYEPCGTVTAKTCKDQLVGQKFSSLLEG-CYAKCPDSAPYLDENTMKCVSLSE-CS 1646
Query: 411 CWANGTYHEAGSEFWADGTCSQWCRCGPG 439
C+ N G + C + C C G
Sbjct: 1647 CFYNDVIPAGGV---IEDNCGRTCYCIAG 1672
Score = 85.5 bits (210), Expect = 3e-16
Identities = 105/457 (22%), Positives = 172/457 (37%), Gaps = 55/457 (12%)
Query: 5 ECGLACSNPQIPGTDWVDMEGAAMLYNGQPLKVLLPLLSPDPCHGVTCRPQETCKEQGG- 63
EC C+ P+ D + +G +L P + + P C Q TC++
Sbjct: 789 ECVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGEVREGPCGSQCTCQDAKWS 848
Query: 64 --QGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLTPF---- 117
+ +C C + G +FDG K++F G C+++ +S + L P
Sbjct: 849 CTEALC----PGRCKVEGSS-LTTFDGVKYNFPGNCHFLAVHNEDWSISVE-LRPCPSGQ 902
Query: 118 TVTTKNE-----NRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADG 172
T T N N P YV ++ ++ D K+R G +
Sbjct: 903 TGTCLNSVTLLLNSSVPVDKYV-------FNSDGTVTND---KIRNQGYYYS-------D 945
Query: 173 RISVAQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQV 229
+I + +S L V + LQ+ ++ V++P + GLCG+ + +D +
Sbjct: 946 KIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFM 1005
Query: 230 FPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGG 289
L + + SW C SC + +++ + CG L + G
Sbjct: 1006 SSQNILEKTSQAFANSWEMMS----CPKGNPSSCISIEKEKFAERH----CGILL-DSSG 1056
Query: 290 PFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVVIEDWRAQVGCE 349
P +CH V P+ + + C C D LC L +YV AC I WR + CE
Sbjct: 1057 PLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGL-CE 1115
Query: 350 ITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQC-DAGFVLSADRCVPLNNG 408
+CP ++ C +SC S + E V+GC C DA + + CV L +
Sbjct: 1116 HSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCV-LKSQ 1174
Query: 409 CGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVC 445
C C+ N + G D +C G L+C
Sbjct: 1175 CDCYINDEVMQPGKLIHIDDN-----KCVCRDGILLC 1206
Score = 61.2 bits (147), Expect = 7e-09
Identities = 52/200 (26%), Positives = 83/200 (41%), Gaps = 33/200 (16%)
Query: 1060 FATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAV-KPWRTDS--F 1116
F C V + S ++ D Q DK C + + + C + G + WR+DS
Sbjct: 697 FEKCGKVAALSNDYKMICIDEYCQTRDKTSTCDTYSELSRLCASDGPGTFESWRSDSDVV 756
Query: 1117 CPLH-CPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLL----SQGVCIPV 1171
C CP Y C + +C+ ++ + C GC C + +LL +G C+
Sbjct: 757 CGTQRCPEQHIYKECGPSNPATCSNVAPFQD--SECVSGCTCPEGYLLDDIGEKGKCVLK 814
Query: 1172 QDCGCTHNGR-YLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWA 1230
+C C +G Y P + C +C+C + +C A C PGR C+V+
Sbjct: 815 AECPCESSGTVYQP--GEVREGPCGSQCTCQDAK-WSCTEALC-PGR-CKVE-------- 861
Query: 1231 TRGLCVLSVGANLTTFDGAR 1250
G++LTTFDG +
Sbjct: 862 ---------GSSLTTFDGVK 872
Score = 60.1 bits (144), Expect = 1e-08
Identities = 58/235 (24%), Positives = 97/235 (41%), Gaps = 26/235 (11%)
Query: 1151 CFEGCECDDRFLL-SQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQ 1209
C GC C + + S+G+C+ DC C+ GR S+ + C+E C+C S +C
Sbjct: 1253 CKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYD-EGSVTSVGCNE-CTCIKGSW-SCT 1309
Query: 1210 AAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQ 1269
C +C + E ++ TFDG + Y G +
Sbjct: 1310 QNECQT--ICHIYGEG----------------HVRTFDGKSYSFDGLCQYSFLEDYCGHE 1351
Query: 1270 NTIPWYRVVAE-VQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASV 1328
N +R++ E V C ++ + FQD + L K V E A+
Sbjct: 1352 NGT--FRILTESVPCCEDGLTCSRKIIVAFQDQNIVLQDGKVTAVKSTE-SKKCELNANA 1408
Query: 1329 SVSRTPDGSLLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTNDW 1383
T L+++ + G+ V N +++VI+ + GK+CG CGN +GD +D+
Sbjct: 1409 YSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDF 1463
>gi|239755776 PREDICTED: similar to Mucin-19 [Homo sapiens]
Length = 1950
Score = 134 bits (336), Expect = 8e-31
Identities = 143/552 (25%), Positives = 210/552 (38%), Gaps = 99/552 (17%)
Query: 307 CVLDVCMGGGDHDILCKALASYVAACQAAGV-VIEDWRAQ--VGCEIT-CPENSHYEVCG 362
C+ + C D C + C + G E WR+ V CE CPE Y+ CG
Sbjct: 692 CIDEYCQTR-DKTSTCDTYSELSRLCASDGPGTFESWRSDSDVVCETQRCPEQHIYKECG 750
Query: 363 PPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLS----ADRCVPLNNGCGCWANGTYH 418
P PA+C + AP + CV GC C G++L +CV L C C ++GT +
Sbjct: 751 PSNPATCSNVAPFQ-----DSECVSGCTCPEGYLLDDIGEKGKCV-LKAECPCESSGTVY 804
Query: 419 EAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWG 478
+ G +G C C C S CT A C C+ G
Sbjct: 805 QPGEV--REGPCGSQCTCQDAKWS--CTEALC--------------------PGRCKVEG 840
Query: 479 DPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGS-QAVSYTRSVTL- 536
T DG +++F G C +L + E+++++V S Q + SVTL
Sbjct: 841 SS-LTTFDGVKYNFPGNCHFLA--------VHNEDWSISVELRPCPSGQTGTCLNSVTLL 891
Query: 537 ---------QIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGL 587
++N T++ K++ G + + Q+ + ++L V T +
Sbjct: 892 LNSSVPVDKYVFNSDGTVTND---KIRNQGYYYSDKIQIFNASSSYLQ-----VETYFHV 943
Query: 588 SLAFDGDSFVRLRV--PAAYAASLCGLCGNYNQDPADDL--------KAVGGKPAGWQVG 637
L ++L V P GLCG+YN DD K W++
Sbjct: 944 KLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEM- 1002
Query: 638 GAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLD 697
C K PS C ++E F CG++ + GPLA CH +V P Y + C
Sbjct: 1003 --MSC----PKGNPSSCISIEKEKFAERH-CGILLDSSGPLASCHPIVNPKPYHEECKKY 1055
Query: 698 ACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCP 757
C + LC + YV AC + W R C CP+ ++ +C SC
Sbjct: 1056 TCTCENSQDCLCTILGNYVKACAEKETYIVGW-RTGLCEHSCPSGLVFKYNVKACNSSCR 1114
Query: 758 SLSAPE---GCESACREGCVC-DAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGP-- 811
SLS + E +GC C DA + + CV QC C Y EV PG
Sbjct: 1115 SLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDC------YINDEVMQPGKLI 1168
Query: 812 -ECERRCECGPG 822
+ +C C G
Sbjct: 1169 HTDDNKCVCRDG 1180
Score = 131 bits (329), Expect = 5e-30
Identities = 139/589 (23%), Positives = 206/589 (34%), Gaps = 92/589 (15%)
Query: 650 CPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLC 709
CP+ + G CG ++A Y C+ + CQ + C
Sbjct: 660 CPNAVGKSYEVCEDGIQKCGKVAALSN------------DYKMICIDEYCQTRDKTS-TC 706
Query: 710 PAVATYVAACQAAGAQLGEWRRPD---FCPLQ-CPAHSHYELCGDSCPVSCPSLSAPEGC 765
+ C + G E R D C Q CP Y+ CG S P +C +++ +
Sbjct: 707 DTYSELSRLCASDGPGTFESWRSDSDVVCETQRCPEQHIYKECGPSNPATCSNVAPFQ-- 764
Query: 766 ESACREGCVCDAGFVLSG----DTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGP 821
+S C GC C G++L CV +C C G Y GEV R CG
Sbjct: 765 DSECVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGEV--------REGPCG- 815
Query: 822 GGHVTCQEGAACGPHEECRLEDGVQACHATGC-GRCLANGGIHYITLDGRVYDLHGSCSY 880
+C +D +C C GRC G T DG Y+ G+C +
Sbjct: 816 ---------------SQCTCQDAKWSCTEALCPGRCKVEGS-SLTTFDGVKYNFPGNCHF 859
Query: 881 VLAQVCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAV 940
+ +ED+SI +E Q V+L V VD V
Sbjct: 860 LAVH-------NEDWSISVELRPCPSGQ---TGTCLNSVTLLLNSSVPVDKYVFNSDGTV 909
Query: 941 GRVRVTAEG------------RNMVLQTTK----GLRLLFDGDAHLLMSIPSPFRGRLCG 984
++ +G + LQ L++ L +S+P G
Sbjct: 910 TNDKIRNQGYYYSDKIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVG 969
Query: 985 LCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEGCGPQGCPVCLAEETAPY 1044
LCG++N DDF+ + + F +W + KG P C E+ A
Sbjct: 970 LCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMSCPKG-----NPSSCISIEKEKFA-- 1022
Query: 1045 ESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAA 1104
CG L + GP A+C +++P Y +C C + + LC L Y AC
Sbjct: 1023 --ERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEK 1080
Query: 1105 GVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGL-TGCTTR--CFEGCECDD-R 1160
+ WRT C CP+ + + C SC +LS C +GC C D
Sbjct: 1081 ETYIVGWRT-GLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAM 1139
Query: 1161 FLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQ 1209
+ ++G C+ C C N + + T D +C C L CQ
Sbjct: 1140 YQNNEGNCVLKSQCDCYINDEVMQPGKLIHTDD--NKCVCRDGI-LLCQ 1185
Score = 103 bits (258), Expect = 9e-22
Identities = 86/315 (27%), Positives = 126/315 (40%), Gaps = 55/315 (17%)
Query: 978 FRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEGCGPQGCPVCL 1037
F+G++CGLCGN NG+ DDF S AS FG +W+ +S+ C +
Sbjct: 1260 FQGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWK---TSQECSD----------T 1306
Query: 1038 AEETAPYESN--------EACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCA--QKGDK 1087
+T P +SN C LR+ F C + PS Y C+ + CA +G
Sbjct: 1307 VAQTFPCDSNPYCKAWAVRKCEILRD--STFRDCHNKVDPSAYHDVCIEEACACDMEGKY 1364
Query: 1088 AFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHS-------HYSIC----TRTCQG 1136
C ++A Y AC A GV V WR + CP++C ++ HY C +TC+
Sbjct: 1365 LGFCTAVAMYAEACSAVGVCVS-WRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKD 1423
Query: 1137 SCAA---LSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSD 1193
S L GC +C + D + C+ + +C C +N +P ++ +
Sbjct: 1424 QLVGQKFSSLLEGCYAKCPDSAPYLDENTMK---CVSLSECSCFYND-VIPA-GGVIEDN 1478
Query: 1194 CSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGAT 1253
C C C + L C P V T +LS GA +T G
Sbjct: 1479 CGRTCYCIAGQ-LECSET-APTNSTFAVS-------TTTATTILSTGAAITLVTGGPSTA 1529
Query: 1254 TS-PGVYELSSRCPG 1267
S P + SS G
Sbjct: 1530 ASIPAITTSSSETTG 1544
Score = 94.7 bits (234), Expect = 5e-19
Identities = 75/256 (29%), Positives = 106/256 (41%), Gaps = 38/256 (14%)
Query: 600 RVPAAYAASLCGLCGNYNQDPADDLK------AVGGKPAGWQVGGAQGCGECVSKPCPSP 653
++ A+ +CGLCGN N D DD A G G +Q C + V++ P
Sbjct: 1255 KIIVAFQGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQTFPCD 1314
Query: 654 CTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDAC--QVQGHPGGLCPA 711
P + C ++ D CH V P+ Y C+ +AC ++G G C A
Sbjct: 1315 SNPYCKA--WAVRKCEILR--DSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTA 1370
Query: 712 VATYVAACQAAGAQLGEWRRPDFCPLQCPAHS-------HYELCGDSCPVSCPS------ 758
VA Y AC A G + WR+P+ CP+ C ++ HYE CG +C
Sbjct: 1371 VAMYAEACSAVGVCV-SWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQK 1429
Query: 759 -LSAPEGCESACREGCVCDAGFVLSGDT--CVPVGQCGCLHDGRYYPLGEVFYPGPECER 815
S EGC + C D+ L +T CV + +C C ++ P G V C R
Sbjct: 1430 FSSLLEGCYAKCP-----DSAPYLDENTMKCVSLSECSCFYND-VIPAGGVI--EDNCGR 1481
Query: 816 RCECGPGGHVTCQEGA 831
C C G + C E A
Sbjct: 1482 TCYC-IAGQLECSETA 1496
Score = 85.9 bits (211), Expect = 3e-16
Identities = 105/457 (22%), Positives = 172/457 (37%), Gaps = 55/457 (12%)
Query: 5 ECGLACSNPQIPGTDWVDMEGAAMLYNGQPLKVLLPLLSPDPCHGVTCRPQETCKEQGG- 63
EC C+ P+ D + +G +L P + + P C Q TC++
Sbjct: 767 ECVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGEVREGPCGSQCTCQDAKWS 826
Query: 64 --QGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLTPF---- 117
+ +C C + G +FDG K++F G C+++ +S + L P
Sbjct: 827 CTEALC----PGRCKVEGSS-LTTFDGVKYNFPGNCHFLAVHNEDWSISVE-LRPCPSGQ 880
Query: 118 TVTTKNE-----NRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADG 172
T T N N P YV ++ ++ D K+R G +
Sbjct: 881 TGTCLNSVTLLLNSSVPVDKYV-------FNSDGTVTND---KIRNQGYYYS-------D 923
Query: 173 RISVAQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQV 229
+I + +S L V + LQ+ ++ V++P + GLCG+ + +D +
Sbjct: 924 KIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFM 983
Query: 230 FPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGG 289
L + + SW C SC + +++ + CG L +G
Sbjct: 984 SSQNILEKTSQAFANSWEMMS----CPKGNPSSCISIEKEKFAERH----CGILLDSSG- 1034
Query: 290 PFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVVIEDWRAQVGCE 349
P +CH V P+ + + C C D LC L +YV AC I WR + CE
Sbjct: 1035 PLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGL-CE 1093
Query: 350 ITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQC-DAGFVLSADRCVPLNNG 408
+CP ++ C +SC S + E V+GC C DA + + CV L +
Sbjct: 1094 HSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCV-LKSQ 1152
Query: 409 CGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVC 445
C C+ N + G D +C G L+C
Sbjct: 1153 CDCYINDEVMQPGKLIHTDDN-----KCVCRDGILLC 1184
Score = 67.4 bits (163), Expect = 9e-11
Identities = 63/243 (25%), Positives = 95/243 (39%), Gaps = 24/243 (9%)
Query: 208 SYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCP 267
++ G VCGLCGN + + +D ++A +G SW+ C D + P C
Sbjct: 1259 AFQGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKT---SQECSDTVAQTFP-CD 1314
Query: 268 EDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGG--GDHDILCKAL 325
+ + C L T F CH V P ++ C+ + C G + C A+
Sbjct: 1315 SNPYCKAWAVRKCEILRDST---FRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAV 1371
Query: 326 ASYVAACQAAGVVIEDWRAQVGCEITCPENS-------HYEVCGPPCPASCPSP-APLTT 377
A Y AC A GV + WR C + C + HYE CG +C
Sbjct: 1372 AMYAEACSAVGVCV-SWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQKF 1430
Query: 378 PAVCEGPCVEGCQCDAGFV-LSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRC 436
++ EG C C A ++ + +CV L+ C C+ N G + C + C C
Sbjct: 1431 SSLLEG-CYAKCPDSAPYLDENTMKCVSLSE-CSCFYNDVIPAGGV---IEDNCGRTCYC 1485
Query: 437 GPG 439
G
Sbjct: 1486 IAG 1488
Score = 60.1 bits (144), Expect = 1e-08
Identities = 51/197 (25%), Positives = 82/197 (41%), Gaps = 33/197 (16%)
Query: 1063 CQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAV-KPWRTDS--FCPL 1119
C V + S ++ D Q DK C + + + C + G + WR+DS C
Sbjct: 678 CGKVAALSNDYKMICIDEYCQTRDKTSTCDTYSELSRLCASDGPGTFESWRSDSDVVCET 737
Query: 1120 H-CPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLL----SQGVCIPVQDC 1174
CP Y C + +C+ ++ + C GC C + +LL +G C+ +C
Sbjct: 738 QRCPEQHIYKECGPSNPATCSNVAPFQD--SECVSGCTCPEGYLLDDIGEKGKCVLKAEC 795
Query: 1175 GCTHNGR-YLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATRG 1233
C +G Y P + C +C+C + +C A C PGR C+V+
Sbjct: 796 PCESSGTVYQP--GEVREGPCGSQCTCQDAK-WSCTEALC-PGR-CKVE----------- 839
Query: 1234 LCVLSVGANLTTFDGAR 1250
G++LTTFDG +
Sbjct: 840 ------GSSLTTFDGVK 850
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.138 0.470
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 68,133,893
Number of Sequences: 37866
Number of extensions: 3825689
Number of successful extensions: 13954
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 47
Number of HSP's successfully gapped in prelim test: 249
Number of HSP's that attempted gapping in prelim test: 10279
Number of HSP's gapped (non-prelim): 2088
length of query: 1403
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1288
effective length of database: 13,892,928
effective search space: 17894091264
effective search space used: 17894091264
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.