Guide to the Human Genome
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Search of human proteins with 239757128

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239757128 PREDICTED: similar to mCG141871 [Homo sapiens]
         (306 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239757128 PREDICTED: similar to mCG141871 [Homo sapiens]           633   0.0  
gi|113428072 PREDICTED: similar to mCG141871 [Homo sapiens]           633   0.0  
gi|113428456 PREDICTED: similar to mCG141871 [Homo sapiens]           626   e-180
gi|56682966 transforming growth factor, beta receptor III [Homo ...    93   3e-19
gi|47132519 Ras association and pleckstrin homology domains 1 is...    57   2e-08
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    56   3e-08
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    56   5e-08
gi|18079216 CASK interacting protein 1 [Homo sapiens]                  55   6e-08
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    54   1e-07
gi|160707881 formin 2 [Homo sapiens]                                   54   2e-07
gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s...    53   3e-07
gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s...    53   3e-07
gi|85815829 SH3-domain binding protein 1 [Homo sapiens]                53   3e-07
gi|40353727 synaptopodin isoform A [Homo sapiens]                      53   4e-07
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    52   5e-07
gi|14602439 Williams Beuren syndrome chromosome region 14 isofor...    52   7e-07
gi|14602437 Williams Beuren syndrome chromosome region 14 isofor...    52   7e-07
gi|14602435 Williams Beuren syndrome chromosome region 14 isofor...    52   7e-07
gi|14602433 Williams Beuren syndrome chromosome region 14 isofor...    52   7e-07
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]     52   7e-07
gi|60460889 Myb protein P42POP [Homo sapiens]                          52   9e-07
gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Ho...    51   1e-06
gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Ho...    51   1e-06
gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Ho...    51   1e-06
gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Hom...    51   1e-06
gi|66932986 filamin-binding LIM protein-1 isoform b [Homo sapiens]     50   2e-06
gi|66932982 filamin-binding LIM protein-1 isoform a [Homo sapiens]     50   2e-06
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    50   2e-06
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    50   2e-06
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo...    50   3e-06

>gi|239757128 PREDICTED: similar to mCG141871 [Homo sapiens]
          Length = 306

 Score =  633 bits (1633), Expect = 0.0
 Identities = 306/306 (100%), Positives = 306/306 (100%)

Query: 1   MGESAAATASLFQRRRRGRGGRVTFPGGLKGSARFLSFGPPFPAPPAPPFPAAPGPWLRR 60
           MGESAAATASLFQRRRRGRGGRVTFPGGLKGSARFLSFGPPFPAPPAPPFPAAPGPWLRR
Sbjct: 1   MGESAAATASLFQRRRRGRGGRVTFPGGLKGSARFLSFGPPFPAPPAPPFPAAPGPWLRR 60

Query: 61  PLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPSPRWGLALHRCSVTPSSRPAPG 120
           PLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPSPRWGLALHRCSVTPSSRPAPG
Sbjct: 61  PLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPSPRWGLALHRCSVTPSSRPAPG 120

Query: 121 PALALLREGCPADTSVAFPPPPPPSPGAARPARFSFRLRPVFNASVQFLHCQLSRCRRLR 180
           PALALLREGCPADTSVAFPPPPPPSPGAARPARFSFRLRPVFNASVQFLHCQLSRCRRLR
Sbjct: 121 PALALLREGCPADTSVAFPPPPPPSPGAARPARFSFRLRPVFNASVQFLHCQLSRCRRLR 180

Query: 181 GVRRAPAPLTPPPPPPPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPP 240
           GVRRAPAPLTPPPPPPPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPP
Sbjct: 181 GVRRAPAPLTPPPPPPPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPP 240

Query: 241 PRPPKSVPGRAVRPEPPAPAPAALEPAPVVALVLAAFVLGAALAAGLGLVCAHSGTDDLR 300
           PRPPKSVPGRAVRPEPPAPAPAALEPAPVVALVLAAFVLGAALAAGLGLVCAHSGTDDLR
Sbjct: 241 PRPPKSVPGRAVRPEPPAPAPAALEPAPVVALVLAAFVLGAALAAGLGLVCAHSGTDDLR 300

Query: 301 QAGPPV 306
           QAGPPV
Sbjct: 301 QAGPPV 306


>gi|113428072 PREDICTED: similar to mCG141871 [Homo sapiens]
          Length = 358

 Score =  633 bits (1633), Expect = 0.0
 Identities = 306/306 (100%), Positives = 306/306 (100%)

Query: 1   MGESAAATASLFQRRRRGRGGRVTFPGGLKGSARFLSFGPPFPAPPAPPFPAAPGPWLRR 60
           MGESAAATASLFQRRRRGRGGRVTFPGGLKGSARFLSFGPPFPAPPAPPFPAAPGPWLRR
Sbjct: 53  MGESAAATASLFQRRRRGRGGRVTFPGGLKGSARFLSFGPPFPAPPAPPFPAAPGPWLRR 112

Query: 61  PLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPSPRWGLALHRCSVTPSSRPAPG 120
           PLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPSPRWGLALHRCSVTPSSRPAPG
Sbjct: 113 PLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPSPRWGLALHRCSVTPSSRPAPG 172

Query: 121 PALALLREGCPADTSVAFPPPPPPSPGAARPARFSFRLRPVFNASVQFLHCQLSRCRRLR 180
           PALALLREGCPADTSVAFPPPPPPSPGAARPARFSFRLRPVFNASVQFLHCQLSRCRRLR
Sbjct: 173 PALALLREGCPADTSVAFPPPPPPSPGAARPARFSFRLRPVFNASVQFLHCQLSRCRRLR 232

Query: 181 GVRRAPAPLTPPPPPPPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPP 240
           GVRRAPAPLTPPPPPPPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPP
Sbjct: 233 GVRRAPAPLTPPPPPPPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPP 292

Query: 241 PRPPKSVPGRAVRPEPPAPAPAALEPAPVVALVLAAFVLGAALAAGLGLVCAHSGTDDLR 300
           PRPPKSVPGRAVRPEPPAPAPAALEPAPVVALVLAAFVLGAALAAGLGLVCAHSGTDDLR
Sbjct: 293 PRPPKSVPGRAVRPEPPAPAPAALEPAPVVALVLAAFVLGAALAAGLGLVCAHSGTDDLR 352

Query: 301 QAGPPV 306
           QAGPPV
Sbjct: 353 QAGPPV 358


>gi|113428456 PREDICTED: similar to mCG141871 [Homo sapiens]
          Length = 358

 Score =  626 bits (1614), Expect = e-180
 Identities = 304/306 (99%), Positives = 304/306 (99%)

Query: 1   MGESAAATASLFQRRRRGRGGRVTFPGGLKGSARFLSFGPPFPAPPAPPFPAAPGPWLRR 60
           MGESAAATASLFQRRRRGRGGRVTFPGGLKGSARFLSFGPPFPAPPAPPFPAAPGPWLRR
Sbjct: 53  MGESAAATASLFQRRRRGRGGRVTFPGGLKGSARFLSFGPPFPAPPAPPFPAAPGPWLRR 112

Query: 61  PLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPSPRWGLALHRCSVTPSSRPAPG 120
           PLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPSPRWGLALHRCSVTPSSRPAPG
Sbjct: 113 PLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPSPRWGLALHRCSVTPSSRPAPG 172

Query: 121 PALALLREGCPADTSVAFPPPPPPSPGAARPARFSFRLRPVFNASVQFLHCQLSRCRRLR 180
           PALALLREGCPADTSVAFPPPPPPSPGAARPARFSFRLRPVFNASVQFLHCQLSRCRRLR
Sbjct: 173 PALALLREGCPADTSVAFPPPPPPSPGAARPARFSFRLRPVFNASVQFLHCQLSRCRRLR 232

Query: 181 GVRRAPAPLTPPPPPPPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPP 240
           GVRRAPA LTPPPPP PSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPP
Sbjct: 233 GVRRAPAHLTPPPPPLPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPP 292

Query: 241 PRPPKSVPGRAVRPEPPAPAPAALEPAPVVALVLAAFVLGAALAAGLGLVCAHSGTDDLR 300
           PRPPKSVPGRAVRPEPPAPAPAALEPAPVVALVLAAFVLGAALAAGLGLVCAHSGTDDLR
Sbjct: 293 PRPPKSVPGRAVRPEPPAPAPAALEPAPVVALVLAAFVLGAALAAGLGLVCAHSGTDDLR 352

Query: 301 QAGPPV 306
           QAGPPV
Sbjct: 353 QAGPPV 358


>gi|56682966 transforming growth factor, beta receptor III [Homo
           sapiens]
          Length = 851

 Score = 92.8 bits (229), Expect = 3e-19
 Identities = 71/246 (28%), Positives = 108/246 (43%), Gaps = 20/246 (8%)

Query: 63  FSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPSPRWGLALHRCSVTPSSRPAPGPA 122
           F+++L +T+       G   VP +  V+V+ ++ +     G A+  C ++P S P     
Sbjct: 593 FNMELYNTDLFLVPSQGVFSVPENGHVYVEVSVTKAEQELGFAIQTCFISPYSNPDRMSH 652

Query: 123 LALLREGCPADTSVAFPPPPP---PSPGA-ARPARFSFRLRPVFNASVQFLHCQLSRCRR 178
             ++   CP D SV F  P     P P A     RFSF  +PVFN S+ FL C+L+ C +
Sbjct: 653 YTIIENICPKDESVKFYSPKRVHFPIPQADMDKKRFSFVFKPVFNTSLLFLQCELTLCTK 712

Query: 179 LRGVRRAPAPLTPPPPPPPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPR 238
           +              P    +C+P DEAC    S  A  + A   +  T T+P+ V +  
Sbjct: 713 ME-----------KHPQKLPKCVPPDEACT---SLDASIIWAMMQNKKTFTKPLAV-IHH 757

Query: 239 PPPRPPKSVPGRAVRPEPPAPAPAALEPAPVVALVLAAFVLGAALAAGLGLVCAHSGTDD 298
                 K    +   P  P P    L+   V+ +  AAFV+GA L   L  + +H+G   
Sbjct: 758 EAESKEKGPSMKEPNPISP-PIFHGLDTLTVMGIAFAAFVIGALLTGALWYIYSHTGETA 816

Query: 299 LRQAGP 304
            RQ  P
Sbjct: 817 GRQQVP 822


>gi|47132519 Ras association and pleckstrin homology domains 1
           isoform 1 [Homo sapiens]
          Length = 1250

 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 68/252 (26%), Positives = 93/252 (36%), Gaps = 38/252 (15%)

Query: 40  PPFPAPPAP--------PFPAAPG-PWLRRPLFSLKLSDTEDVF------PRRAGPLEVP 84
           PP P PP P        P P AP  P    P   LK+   + +       P    P+  P
Sbjct: 713 PPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAP 772

Query: 85  ADSRVFVQAALARPSPRWGLALHRCSVTPSSRPAPGPAL--ALLREGCPADTSVAFPPPP 142
              +   +  +  P+P     +    VT ++ P P P +  A  +   PA      PP P
Sbjct: 773 LPPQAPPKPLVTIPAPTSTKTVAPV-VTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTP 831

Query: 143 P-PSPGAARPARFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAPAPLTPPPPPPPSRCL 201
           P P P    P + SF  +P  +         LS    +  V++  +   PPP PP     
Sbjct: 832 PVPVPPPTLPKQQSFCAKPPPSP--------LSPVPSV--VKQIASQFPPPPTPPAMESQ 881

Query: 202 PQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRP--PPRPPKSVPGRAVRPEPPAP 259
           P     A+    S   + A         QP  + VP P  PP PP+S       P PP+P
Sbjct: 882 PLKPVPANVAPQSPPAVKAKPKW-----QPSSIPVPSPDFPPPPPES--SLVFPPPPPSP 934

Query: 260 APAALEPAPVVA 271
            PA   P P  A
Sbjct: 935 VPAPPPPPPPTA 946



 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 66/242 (27%), Positives = 91/242 (37%), Gaps = 50/242 (20%)

Query: 40  PPFPAPPAPPFPAAPGPWL----------RRPLFSLKLSDTE-DVFPRRAGPLEVPADSR 88
           PP P PP PP P  P P L            P+F    + T      + +G L  P    
Sbjct: 631 PPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPP 690

Query: 89  VFVQAALARPSPRWGLALHRCSVTPSSRPAPGPALALLREGCPADTSVAFPPPPPPSPGA 148
           V +Q+   +P         +  V P+    P P                 PPPPPP+PG+
Sbjct: 691 V-MQSQSVKP---------QILVPPNGVVPPPP-----------------PPPPPPTPGS 723

Query: 149 A----RPARFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAPAPLTPPPPPPPSRCLPQD 204
           A    +PA  +  L P F+A    L  ++ + + +  V    AP TPPPPPP    LP  
Sbjct: 724 AMAQLKPAPCAPSL-PQFSAPPPPL--KIHQVQHITQV----APPTPPPPPPIPAPLPPQ 776

Query: 205 EACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPPPRPPKSVPGRAVRPEPPAPAPAAL 264
                  +  A         + T   P   T P PP +   + P   + P PP P P  +
Sbjct: 777 APPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTP-PVPV 835

Query: 265 EP 266
            P
Sbjct: 836 PP 837



 Score = 49.3 bits (116), Expect = 4e-06
 Identities = 55/191 (28%), Positives = 69/191 (36%), Gaps = 23/191 (12%)

Query: 111 VTPSSRPAPGPALALLREGCPADTSVAFPPPPP------PSPGAARPARFSF----RLRP 160
           VTP +   P P L       P       PPPPP      PS G+A P    +    RL+ 
Sbjct: 616 VTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQN 675

Query: 161 VFNASVQFLHCQLSRCRRLRGVRRA----PAPLTPPPPPPPSRCLPQDEACADTGSGSAE 216
               S            + + V+      P  + PPPPPPP    P         +  A 
Sbjct: 676 ASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAP 735

Query: 217 GL---AADGPHL--HTLTQPIVVTVPRPPPRPPKSVPGRAVRPEPPAPAPAALEPAPVVA 271
            L   +A  P L  H +     V  P PPP PP   P   + P+ P P P    PAP   
Sbjct: 736 SLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAP---LPPQAP-PKPLVTIPAPTST 791

Query: 272 LVLAAFVLGAA 282
             +A  V  AA
Sbjct: 792 KTVAPVVTQAA 802



 Score = 38.5 bits (88), Expect = 0.008
 Identities = 54/219 (24%), Positives = 76/219 (34%), Gaps = 19/219 (8%)

Query: 41   PFPAPPAPPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPSP 100
            P PAPP PP P A     +      K S T     ++  P     +S +   +    P P
Sbjct: 934  PVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTP-QRNSSIKSSSGAEHPEP 992

Query: 101  RWGLALHRCSVTPSSRPAPGPALALLREGCPADTSVAFPPPPPPSPGAARPARFSFRLRP 160
            +      R SV         PA      G P+  ++  PP  PP PG    +     L  
Sbjct: 993  K------RPSVDSLVSKFTPPA----ESGSPSKETLP-PPAAPPKPGKLNLS--GVNLPG 1039

Query: 161  VFNASVQFLHCQLSRCRRLRGVRRAPAPLT----PPPPPPPSRCLPQDEACADTGSGSAE 216
            V           +   R    V   P+P +    PPPPP     LP  E  A     ++ 
Sbjct: 1040 VLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSP 1099

Query: 217  GLAADGPHLHTLTQPIVVTVPRPPPRPPKSVPGRAVRPE 255
             +A   P     ++  V   P PP RP ++   R  + E
Sbjct: 1100 KVAVVNPQPQQWSKMSVKKAP-PPTRPKRNDSTRLTQAE 1137



 Score = 37.4 bits (85), Expect = 0.017
 Identities = 73/288 (25%), Positives = 94/288 (32%), Gaps = 66/288 (22%)

Query: 43   PAPPAPPFPAAPGPWLRRPLFSLK-----LSDTEDV-------FPRRAGPLEVPADSRVF 90
            P+PP PP P  P    ++  F  K     LS    V       FP    P  + +     
Sbjct: 826  PSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKP 885

Query: 91   VQAALARPSPRWGLALHRCSVTPSSRPAPGPAL------ALLREGCPADTSVAFPPPPPP 144
            V A +A  SP    A  +    PSS P P P        + L    P  + V  PPPPPP
Sbjct: 886  VPANVAPQSPPAVKAKPKWQ--PSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPP 943

Query: 145  ---------------------SPGAARPARFSFRLRPVFNASVQFLHCQLSRCRRLRGVR 183
                                 SPG  +P        P  N+S++          +   V 
Sbjct: 944  PTASPTPDKSGSPGKKTSKTSSPGGKKPPP-----TPQRNSSIKSSSGAEHPEPKRPSVD 998

Query: 184  RAPAPLTPPPP--PPPSRCLPQDEACADTGSGSAEG-----------LAADGPHLHTLTQ 230
               +  TPP     P    LP   A    G  +  G           ++A  P L    +
Sbjct: 999  SLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGK 1058

Query: 231  PIVVTVPRPPPR---PPKSVPGRAVRPEPPAPAPAAL--EPAPVVALV 273
              VV  P PP     PP   P     P PP   PA      +P VA+V
Sbjct: 1059 DSVVEFPSPPSDSDFPPP--PPETELPLPPIEIPAVFSGNTSPKVAVV 1104



 Score = 32.3 bits (72), Expect = 0.54
 Identities = 16/51 (31%), Positives = 19/51 (37%)

Query: 228 LTQPIVVTVPRPPPRPPKSVPGRAVRPEPPAPAPAALEPAPVVALVLAAFV 278
           +  P   + P PP  PP   P     P PP P P   + AP        FV
Sbjct: 615 IVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFV 665



 Score = 31.2 bits (69), Expect = 1.2
 Identities = 14/44 (31%), Positives = 20/44 (45%)

Query: 225 LHTLTQPIVVTVPRPPPRPPKSVPGRAVRPEPPAPAPAALEPAP 268
           + ++ +P    VP   P+P    P  A +P PP P P    P P
Sbjct: 595 MESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPP 638



 Score = 29.3 bits (64), Expect = 4.6
 Identities = 24/91 (26%), Positives = 29/91 (31%), Gaps = 34/91 (37%)

Query: 178 RLRGVRRAPAPLTPPPPPPPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVP 237
           R+  + R    L PP  P P    P                       +T +QP   + P
Sbjct: 594 RMESMNRPYTSLVPPLSPQPKIVTP-----------------------YTASQP---SPP 627

Query: 238 RPPPRPPKSVPGRAVRPEPPAPAPAALEPAP 268
            PPP PP         P PP P P    P P
Sbjct: 628 LPPPPPPP--------PPPPPPPPPPPPPLP 650


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 56.2 bits (134), Expect = 3e-08
 Identities = 80/282 (28%), Positives = 100/282 (35%), Gaps = 71/282 (25%)

Query: 39  GPPFPAPPAPPFPAAPGP---------------------------WLRRPLF-SLKLSDT 70
           G P PAP A P P   GP                            L+RP   SL  S T
Sbjct: 179 GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSAT 238

Query: 71  EDVFPRRAGPLEVPADSRVFVQAALARPSPRWGLALHRCSVTPSSRPAPGPALALLREGC 130
               P R+GP    A       A  ++P P+   AL    VTP  + A  PAL  L    
Sbjct: 239 PLSSPARSGP---SARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDA-APALGPLSSSP 294

Query: 131 PADTSVAFPPPPP--------PSPGAARPARFSFRL-RPVFNASVQFLHCQLSRCRRLRG 181
            A  S + PP P         PSP A  P++ +  L  P   A+  FL            
Sbjct: 295 LATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFL------------ 342

Query: 182 VRRAPAP-----LTPPPPPPPSRCLPQDEA-CADTGSGSAEGLAADGPHLHTLTQPIVVT 235
               P+P      TPPP  PP+  LP  +A  +   S     LA   P         ++ 
Sbjct: 343 ----PSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ 398

Query: 236 VP-RPPPRPPKSVP-----GRAVRPE--PPAPAPAALEPAPV 269
            P  PPP PP   P        V P   PP+ AP +L   P+
Sbjct: 399 APFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPL 440



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 87/312 (27%), Positives = 111/312 (35%), Gaps = 66/312 (21%)

Query: 3   ESAAATASLFQRRRRGRGGRVTFPGG--LKGSARFLSF----GPPFPAPP-APPFPAAPG 55
           E +    S   RRR   GG +  P    L  SA  LS     GP     P AP  P+ P 
Sbjct: 205 EHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPK 264

Query: 56  PW----LRRPLFSLKLSDTEDVF-PRRAGPLEVPADSRVFVQAALARPSPRWGLALHRCS 110
           P     LR P  +    D      P  + PL  P+ S        A PSP    +L    
Sbjct: 265 PKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPS--------APPSPSAPPSLQTLP 316

Query: 111 VTPSSRPA------------------PGPALALLREGCP-ADTSVAFPP-PPPPSPGAAR 150
             P++ P+                  P P L+ L    P A  ++A PP   PPSP A+ 
Sbjct: 317 SPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASP 376

Query: 151 PARFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAPAPLTPPPPPPPSRCLPQDEACADT 210
           P      L P+   S Q              V    AP +PPP PP     P     +  
Sbjct: 377 P------LSPLATPSPQ--------APNALAVHLLQAPFSPPPSPPVQA--PFSPPASPP 420

Query: 211 GSGSAEGLAADGPHLHTLTQPIVVTVPRPPPR------PPKSVPGRAVRP----EPPAPA 260
            S SA   +   P L      +  + P  PP       PP++ P  A  P    +PP  A
Sbjct: 421 VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQA 480

Query: 261 PAALEPAPVVAL 272
           P AL   P+ AL
Sbjct: 481 PPALATPPLQAL 492



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 81/321 (25%), Positives = 100/321 (31%), Gaps = 92/321 (28%)

Query: 41  PFPAPPAPPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPSP 100
           PF  PP+PP  A   P    P+       ++      A PL+VP             PSP
Sbjct: 400 PFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP-------------PSP 446

Query: 101 RWGLALHRCSVTPSSRPAP--GPALALLREGCPADTSVAFPPPPP-PSPGAARPARFSF- 156
                +   +  P   P P   P L L +    A  ++A PP    PSP A+ P +  F 
Sbjct: 447 PASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFS 506

Query: 157 ---------------RLRPVFNASVQFLHCQLSRCRRLRGVRRAPAP------------- 188
                          +  PV  A +  +         L+  RR P P             
Sbjct: 507 PSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTL 566

Query: 189 -LTPPPPPPPSR-----------------CLPQDEACADTGSGSAEGLAADGP---HLHT 227
            L P PPPPPSR                      E      SG   G AA  P    L  
Sbjct: 567 ALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAA 626

Query: 228 LTQPIVVTVPRPP-----------PRPPKSVPGRA---------VRPEPPAPAPAALEPA 267
                    P PP           P PP + PG A           PE   PAP AL+P 
Sbjct: 627 CHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPG 686

Query: 268 PVVALVLAAFVLGAALAAGLG 288
           P      +    G   AAG G
Sbjct: 687 P------SPGTSGGKAAAGAG 701


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 55.8 bits (133), Expect = 5e-08
 Identities = 77/266 (28%), Positives = 107/266 (40%), Gaps = 38/266 (14%)

Query: 39  GPPFPAPPAPPFPAAPGPWLRRPLFSLKLSDTEDVFP--RR----AGPLEVPADSRVFVQ 92
           G P PAP A P P   GP  R+ + S     T +  P  RR     G L+ PA SR    
Sbjct: 188 GLPRPAPSARPRPPTEGP--RKSVSSASEHSTTEPSPAARRRPSAGGGLQRPA-SRSLSS 244

Query: 93  AALARPSP-RWGLALHRCSVTPS--SRPAPGPALAL--------LREGCPADTSVAFPPP 141
           +A    SP R G +       P+  S+P P    AL         ++  PA   ++  P 
Sbjct: 245 SATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPL 304

Query: 142 PPPSPGAARPARFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAPAPLTPPPP--PPPSR 199
             PSP AA  ++    L    ++S   L CQL+           P PL PP P  PP  +
Sbjct: 305 ATPSPSAALQSQAPPTLPATPHSS--SLTCQLA----------TPLPLAPPSPSAPPSLQ 352

Query: 200 CLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPPPRPPK--SVPGRAVRPEPP 257
            LP   A   + + ++ G          L  P +  +  PPP+ P   ++P     P PP
Sbjct: 353 TLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPP 412

Query: 258 APAPAA--LEPAPVVALVLAAFVLGA 281
           A  P +    P+P     LA  +L A
Sbjct: 413 ASPPLSPLATPSPQAPNALAVHLLQA 438



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 89/323 (27%), Positives = 111/323 (34%), Gaps = 58/323 (17%)

Query: 3   ESAAATASLFQRRRRGRGGRVTFPGG--LKGSARFLSF----GPPFPAPP-APPFPAAPG 55
           E +    S   RRR   GG +  P    L  SA  LS     GP     P AP  P+ P 
Sbjct: 214 EHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPK 273

Query: 56  PW----LRRPLFSLKLSDTEDVF-PRRAGPLEVPADSRVFVQAA---------------- 94
           P     LR P  +    D      P  + PL  P+ S      A                
Sbjct: 274 PKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQ 333

Query: 95  LARPSPRWGLALHRCSVTPS-----SRPAPGPALALLREGCPA-DTSVAFPPPPPPSPGA 148
           LA P P   LA    S  PS     S PA  P+ A    G P    + +F P PP SP A
Sbjct: 334 LATPLP---LAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLA 390

Query: 149 ARPARFSFRLR---------PVFNASVQFLHCQLSRCRRLRGVRRAPAPLTPPPPPPPSR 199
             P +    L          P  +  +  L     +      V    AP +PPP PP   
Sbjct: 391 TPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA 450

Query: 200 CLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPPPR------PPKSVPGRAVR 253
             P     +   S SA   +   P L      +  + P  PP       PP++ P  A  
Sbjct: 451 --PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP 508

Query: 254 P----EPPAPAPAALEPAPVVAL 272
           P    +PP  AP AL   P+ AL
Sbjct: 509 PLQLAKPPPQAPPALATPPLQAL 531



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 81/321 (25%), Positives = 100/321 (31%), Gaps = 92/321 (28%)

Query: 41  PFPAPPAPPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPSP 100
           PF  PP+PP  A   P    P+       ++      A PL+VP             PSP
Sbjct: 439 PFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP-------------PSP 485

Query: 101 RWGLALHRCSVTPSSRPAP--GPALALLREGCPADTSVAFPPPPP-PSPGAARPARFSF- 156
                +   +  P   P P   P L L +    A  ++A PP    PSP A+ P +  F 
Sbjct: 486 PASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFS 545

Query: 157 ---------------RLRPVFNASVQFLHCQLSRCRRLRGVRRAPAP------------- 188
                          +  PV  A +  +         L+  RR P P             
Sbjct: 546 PSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTL 605

Query: 189 -LTPPPPPPPSR-----------------CLPQDEACADTGSGSAEGLAADGP---HLHT 227
            L P PPPPPSR                      E      SG   G AA  P    L  
Sbjct: 606 ALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAA 665

Query: 228 LTQPIVVTVPRPP-----------PRPPKSVPGRA---------VRPEPPAPAPAALEPA 267
                    P PP           P PP + PG A           PE   PAP AL+P 
Sbjct: 666 CHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPG 725

Query: 268 PVVALVLAAFVLGAALAAGLG 288
           P      +    G   AAG G
Sbjct: 726 P------SPGTSGGKAAAGAG 740


>gi|18079216 CASK interacting protein 1 [Homo sapiens]
          Length = 1431

 Score = 55.5 bits (132), Expect = 6e-08
 Identities = 59/175 (33%), Positives = 71/175 (40%), Gaps = 23/175 (13%)

Query: 113  PSSRPAPGPALALLREGCPADTSVAFPPPPPPSPGAARPARFSFRLRPVFNASVQFLH-- 170
            P   P P PA     E  P D +   PP PPP   A +PA+     +PV    V  L   
Sbjct: 1189 PELPPPPPPA-----EPPPTDLA-HLPPLPPPEGEARKPAKPPVSPKPVLTQPVPKLQGS 1242

Query: 171  -CQLSRCRRLRG-----VRRA---PAPLTPPPPPPPSRCLPQDEACADTGSGSAEGLAAD 221
                S+   L G     V+RA   P P++P PPPPP+   P  +A A   SGSA    A 
Sbjct: 1243 PTPTSKKVPLPGPGSPEVKRAHGTPPPVSPKPPPPPTAPKPV-KAVAGLPSGSAGPSPAP 1301

Query: 222  GPHLHTLTQPIVVTVPRPPPRPPKSVPGRAVRPEPPAPAPAALEPAPVVALVLAA 276
             P      QP    + +PP  PP      A  P P APA       P  A   AA
Sbjct: 1302 SP----ARQP-PAALAKPPGTPPSLGASPAKPPSPGAPALHVPAKPPRAAAAAAA 1351



 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 63/244 (25%), Positives = 85/244 (34%), Gaps = 54/244 (22%)

Query: 39   GPPFPAPPAPPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARP 98
            GPP   PP PP    P      P             P   G    PA   V  +  L +P
Sbjct: 1187 GPPELPPPPPPAEPPPTDLAHLP-----------PLPPPEGEARKPAKPPVSPKPVLTQP 1235

Query: 99   SPRWGLALHRCSVTPSSR--PAPGPALALLREGCPADTSVAFPPPPPPSPGAARPARFSF 156
             P+      + S TP+S+  P PGP    ++        V+  PPPPP+  A +P +   
Sbjct: 1236 VPKL-----QGSPTPTSKKVPLPGPGSPEVKRAHGTPPPVSPKPPPPPT--APKPVKAVA 1288

Query: 157  RLRPVFNASVQFLHCQLSRCRRLRGVRRAPAPLTPPPPPPPSRCLPQDEACADTGSGSAE 216
             L P  +A                  R+ PA L  PP  PPS            G+  A+
Sbjct: 1289 GL-PSGSAGPS---------PAPSPARQPPAALAKPPGTPPS-----------LGASPAK 1327

Query: 217  GLAADGPHLHTLTQPIVVTVPRPPPRPPKSVPGRAVRPEPP----APAPAALEPAPVVAL 272
              +   P LH         VP  PPR   +    A  P  P    +P  +A +     + 
Sbjct: 1328 PPSPGAPALH---------VPAKPPRAAAAAAAAAAAPPAPPEGASPGDSARQKLEETSA 1378

Query: 273  VLAA 276
             LAA
Sbjct: 1379 CLAA 1382



 Score = 35.8 bits (81), Expect = 0.049
 Identities = 51/210 (24%), Positives = 70/210 (33%), Gaps = 37/210 (17%)

Query: 79  GPLEVPADSRVFVQAALARPSPRWGLALHRCSVTPSSRPAPGPALALLREGCPADT-SVA 137
           GPL   A   + V A  + P P            P+      P +   ++   +D    A
Sbjct: 616 GPLRRKAPQSLEVMAIESPPPPE-----------PTPADCQSPKMTTFQDSELSDELQAA 664

Query: 138 FPPPPPPSPGAARPARFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAPAPLTPPPPPPP 197
              P    P   +P   S  L P   A+ +       R R +   +       P P  P 
Sbjct: 665 MTGPAEVGPTTEKP---SSHLPPTPRATTRQDSSLGGRARHMSSSQELLGDGPPGPSSPM 721

Query: 198 SRCLPQDEACADTGS--GSAEGLAADGPHLHTLTQPIVVTVP--------------RPPP 241
           SR     E   D G   G+    A  G H H++ +  V  VP               PP 
Sbjct: 722 SR---SQEYLLDEGPAPGTPPREARPGRHGHSIKRASVPPVPGKPRQVLPPGTSHFTPPQ 778

Query: 242 RPPKSVPGRAVR---PEPPAPAPAALEPAP 268
            P K+ PG       P  PAPA A ++P P
Sbjct: 779 TPTKTRPGSPQALGGPHGPAPATAKVKPTP 808



 Score = 32.7 bits (73), Expect = 0.41
 Identities = 43/152 (28%), Positives = 48/152 (31%), Gaps = 39/152 (25%)

Query: 137  AFPPPPPPSPGAARPARFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAPAPLTPPPPPP 196
            A P PPPP                     +   H      RR     +A  P  PPPPPP
Sbjct: 1159 AGPEPPPP---------------------LSVYHNGTGTVRRRPASEQAGPPELPPPPPP 1197

Query: 197  -----------PSRCLPQDEA--CADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPPPRP 243
                       P    P+ EA   A         L    P L     P    VP P P  
Sbjct: 1198 AEPPPTDLAHLPPLPPPEGEARKPAKPPVSPKPVLTQPVPKLQGSPTPTSKKVPLPGPGS 1257

Query: 244  P--KSVPGR--AVRPEPPAPAPAALEPAPVVA 271
            P  K   G    V P+PP P P A +P   VA
Sbjct: 1258 PEVKRAHGTPPPVSPKPP-PPPTAPKPVKAVA 1288


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 76/284 (26%), Positives = 89/284 (31%), Gaps = 55/284 (19%)

Query: 31  GSARFLSFGPPFPAPPAPPFPAAP-GPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRV 89
           G AR    GP  P PP+P  P  P GP    P  + KL    +       P+   A    
Sbjct: 93  GRARPGGGGPQRPGPPSPRRPLVPAGP--APP--AAKLRPPPEGSAGSCAPVPAAAAVAA 148

Query: 90  FVQAALARPSPRWGLALHRCSVTPSSRPAPGPALALLREGCPADTSVAFPPPPPPSPGAA 149
             + A A P+   G A       P   P PGP         P        P  P  PGAA
Sbjct: 149 GPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPG------PG-------PGKPAGPGAA 195

Query: 150 RPARFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAPAPLTPPPPPPPSRCLPQDEACAD 209
           +            N S   L+   +    +  V   PA L P P P              
Sbjct: 196 Q----------TLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKP-------------- 231

Query: 210 TGSGSAEGLAADGPHLHTLTQPIVVTVPRPPPRPPKSVPGRAVRPEPPAPAPAALEP--- 266
               +A G     P       P     P PP  P  + P  A  P PPAPA  A  P   
Sbjct: 232 ----AAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHP 287

Query: 267 ------APVVALVLAAFVLGAALAAGLGLVCAHSGTDDLRQAGP 304
                 AP V    AA   G+A AA      A        Q GP
Sbjct: 288 AGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGP 331



 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 58/211 (27%), Positives = 79/211 (37%), Gaps = 26/211 (12%)

Query: 40  PPFPAPPAPPFPAAPGPWLRRPL---FSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALA 96
           P  P+PPA P PAAP      P     +L         P  A P   P  +     +A A
Sbjct: 252 PAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGA 311

Query: 97  RPSPRWGLALHRCSVTPSSRPAPGPALALLREGCPADTS---VAFPPPPPPSPGAARPAR 153
            P+P             S +P PG A A    G  A++    V   PP   +  A+ PA 
Sbjct: 312 APAPAPAAG---GPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPAS 368

Query: 154 FSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAPAPLTPPPPPPPSRCLPQDEACADTGSG 213
            +  +  V   ++Q             G   +PA + PPP P     LP+  A A T S 
Sbjct: 369 TAASM--VIGPTMQ-------------GALPSPAAV-PPPAPGTPTGLPKGAAGAVTQSL 412

Query: 214 SAEGLAADGPHLHTLTQPIVV-TVPRPPPRP 243
           S    A       TLT  ++   +P+PP  P
Sbjct: 413 SRTPTATTSGIRATLTPTVLAPRLPQPPQNP 443



 Score = 35.4 bits (80), Expect = 0.064
 Identities = 51/222 (22%), Positives = 61/222 (27%), Gaps = 74/222 (33%)

Query: 40  PPFPAPPAPPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPS 99
           PPF    APP PAAP P                           PA       AA   P 
Sbjct: 241 PPFVGAAAPPAPAAPSP---------------------------PAAPAPAAPAAAPPPP 273

Query: 100 PRWGLALHRCSVTPSSRPAPGPAL---ALLREGCPADTSVAFPPPPPPSPGAARPARFSF 156
           P     L R    P+  P   PA+   A  + G  A  +      P P+P A  PA    
Sbjct: 274 PPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAA------PAPAPAAGGPA---- 323

Query: 157 RLRPVFNASVQFLHCQLSRCRRLRGVRRAPAPLTPPPPPPPSRCLPQDEACADTGSGSAE 216
                                   GV   P P      P P       +        +A+
Sbjct: 324 ------------------------GVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQ 359

Query: 217 GLAADGPHLHTLTQ----------PIVVTVPRPPPRPPKSVP 248
            LAA GP     +           P    VP P P  P  +P
Sbjct: 360 TLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLP 401


>gi|160707881 formin 2 [Homo sapiens]
          Length = 1722

 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 65/254 (25%), Positives = 78/254 (30%), Gaps = 82/254 (32%)

Query: 26   PGGLKGSARFLSFGPPFPAPPAPPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPA 85
            P  L+G+       PP P    PP P  PG                      AG L +P 
Sbjct: 899  PPPLQGTEMLPPPPPPLPGAGIPPPPPLPG----------------------AGILPLPP 936

Query: 86   DSRVFVQAALARPSPRWGLALHRCSVTPSSRPAPGPALALLREGCPADTSVAFPPPPPPS 145
                   A +  P P  G A+      P   P PG  + L     P     A  PPPPP 
Sbjct: 937  ----LPGAGIPPPPPLPGAAI------PPPPPLPGAGIPL-----PPPLPGAGIPPPPPL 981

Query: 146  PGAARPARFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAPAPL----TPPPPPPPSRCL 201
            PGA  P        P+  A +                   P PL     PPPPP P   +
Sbjct: 982  PGAGIPPP-----PPLPGAGIP-----------------PPPPLPGAGIPPPPPLPGAGI 1019

Query: 202  PQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPPP------RPPKSVPGRAVRPE 255
            P        G      L   G             +P PPP       PP  +PG  + P 
Sbjct: 1020 PPPPPLPGAGIPPPPPLPGAG-------------IPPPPPLPGAGIPPPPPLPGAGIPPP 1066

Query: 256  PPAPAPAALEPAPV 269
            PP P      P P+
Sbjct: 1067 PPLPGAGIPPPPPL 1080



 Score = 51.6 bits (122), Expect = 9e-07
 Identities = 63/241 (26%), Positives = 75/241 (31%), Gaps = 51/241 (21%)

Query: 40   PPFPAPPAPPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPS 99
            PP P    PP P  PG  +  P             P    P   P        A +  P 
Sbjct: 990  PPLPGAGIPPPPPLPGAGIPPP----------PPLPGAGIPPPPPLPG-----AGIPPPP 1034

Query: 100  PRWGLALHRCSVTPSSRPAPGPALALLREGCPADTSVAFPPPPPPSPGAARPARFSFRLR 159
            P  G  +      P +   P P L       P     A  PPPPP PGA  P        
Sbjct: 1035 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP-----P 1089

Query: 160  PVFNASVQFLHCQLSRCRRLRGVRRAPAPLT----PPPPPPPSRCLPQDEACADTGSGSA 215
            P+  A +                   P PL     PPPPP P   +P        G    
Sbjct: 1090 PLPGAGIP-----------------PPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPP 1132

Query: 216  EGLAADG-PHLHTLTQPIVVTVPRPPPRP------PKSVPGRAVRPEPPAPAPAALEPAP 268
              L   G P    L +   V +P PPP P      P  +PG  + P PP P      P P
Sbjct: 1133 PPLPGAGIPPPPPLPR---VGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPP 1189

Query: 269  V 269
            +
Sbjct: 1190 L 1190



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 45/170 (26%), Positives = 54/170 (31%), Gaps = 42/170 (24%)

Query: 111  VTPSSRPAPGPALALLREGC-----PADTSVAFPPPPPPSPGAARPARFSFRLRPVFNAS 165
            V P   P PG  +  L         P   +   PPPPPP PGA  P        P+  A 
Sbjct: 876  VPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPP-----PPLPGAG 930

Query: 166  VQFLHCQLSRCRRLRGVRRAPAPLTPPPPPPPSRCLPQDEACADTGSGSAEGLAADGPHL 225
            +  L                P    PPPPP P   +P        G      L   G   
Sbjct: 931  ILPL-------------PPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAG--- 974

Query: 226  HTLTQPIVVTVPRPPP------RPPKSVPGRAVRPEPPAPAPAALEPAPV 269
                      +P PPP       PP  +PG  + P PP P      P P+
Sbjct: 975  ----------IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1014



 Score = 48.1 bits (113), Expect = 9e-06
 Identities = 64/242 (26%), Positives = 75/242 (30%), Gaps = 53/242 (21%)

Query: 40   PPFPAPPAPPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPS 99
            PP P    PP P  PG  +  P             P    P   P        A +  P 
Sbjct: 1034 PPLPGAGIPPPPPLPGAGIPPP----------PPLPGAGIPPPPPLPG-----AGIPPPP 1078

Query: 100  PRWGLALHRCSVTPSSRPAPGPALALLREGCPADTSVAFPPPPPPSPGAARPARFSFRLR 159
            P  G  +      P +   P P L  +    P     A  PPPPP PGA  P        
Sbjct: 1079 PLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPP-----P 1133

Query: 160  PVFNASVQFLHCQLSRCRRLRGVRRAPAPLT----PPPPPPPSRCLPQDEACADTGSGSA 215
            P+  A +                   P PL     PPPPP P   +P        G    
Sbjct: 1134 PLPGAGIP-----------------PPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPP 1176

Query: 216  EGLAADG-PHLHTLTQPIVVTVPRPPPRP------PKSVPGRAV--RPEPPAPAPAALEP 266
              L   G P    L     V +P PPP P      P  +PG  +   P PP P P    P
Sbjct: 1177 PPLPGVGIPPPPPLPG---VGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIP 1233

Query: 267  AP 268
             P
Sbjct: 1234 PP 1235



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 46/182 (25%), Positives = 57/182 (31%), Gaps = 46/182 (25%)

Query: 98   PSPRWGLALHRCSVTPSSRPAPGPALALLREGCPADTSVAFPPPPPPSPGAARPARFSFR 157
            P P  G+ +     T   +P P     +L    P        PPPPP PGA         
Sbjct: 880  PPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGI-PPPPPLPGAG-----ILP 933

Query: 158  LRPVFNASVQFLHCQLSRCRRLRGVRRAPAPL----TPPPPPPPSRCLPQDEACADTGSG 213
            L P+  A +                   P PL     PPPPP P   +P        G  
Sbjct: 934  LPPLPGAGIP-----------------PPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIP 976

Query: 214  SAEGLAADGPHLHTLTQPIVVTVPRPPP------RPPKSVPGRAVRPEPPAPAPAALEPA 267
                L   G             +P PPP       PP  +PG  + P PP P      P 
Sbjct: 977  PPPPLPGAG-------------IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1023

Query: 268  PV 269
            P+
Sbjct: 1024 PL 1025



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 38/137 (27%), Positives = 52/137 (37%), Gaps = 22/137 (16%)

Query: 135 SVAFPPPPPP---SPGAARPARFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAPAPLTP 191
           S++ PPPPP    S G  +P       +P  + S +F   Q S    +    +    +  
Sbjct: 806 SISQPPPPPSLLWSAGQGQPGS-----QPPHSISTEF---QTSHEHSVSSAFKNSCNIPS 857

Query: 192 PPPPPPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPPPRPPKSVPGRA 251
           PPP P          C ++ S S  GL    P    L    V T+P      P  + G  
Sbjct: 858 PPPLP----------CTESSS-SMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTE 906

Query: 252 VRPEPPAPAPAALEPAP 268
           + P PP P P A  P P
Sbjct: 907 MLPPPPPPLPGAGIPPP 923


>gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
            sapiens]
          Length = 1858

 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 67/228 (29%), Positives = 83/228 (36%), Gaps = 42/228 (18%)

Query: 45   PPAPPFPAAPGPWL-RRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAA---LARPSP 100
            PP PP P APGP L ++P    + S    V P  A    V   S +  Q A   L  P P
Sbjct: 1627 PPPPPPPPAPGPHLVQQPNSHQQHSVAHVVGPVHA----VTPGSHIHSQTAGHHLPPPPP 1682

Query: 101  RWGLALHRCSVTPSSRPAPGPALALLREGCPAD----TSVAFPPPPPPSPGAARPARFSF 156
              G A       P   P P P+  L  +G  A      + A PPPPPP P +   +    
Sbjct: 1683 PPGPA-------PHHHPPPHPSTGL--QGLQAQHQHVVNSAPPPPPPPPPSSVLASGH-- 1731

Query: 157  RLRPVFNASVQFLHCQLSRCRRLRGVRRAPAPLTPPPPPPPSRCLPQDEACADTGSGSAE 216
                    S Q LH         +G    P+   P  PP PS+           G G   
Sbjct: 1732 -----HTTSAQALHHPPH-----QGPPLFPSSAHPTVPPYPSQATHH----TTLGPGPQH 1777

Query: 217  GLAADGPHLHTLTQPIVVTVPRPPPRPPKSVPGRAVRPEPPAPAPAAL 264
              +  GPH      P+ VT P   P+ P S+P        P P   AL
Sbjct: 1778 QPSGTGPHC-----PLPVTGPHLQPQGPNSIPTPTASGFCPHPGSVAL 1820



 Score = 34.3 bits (77), Expect = 0.14
 Identities = 28/108 (25%), Positives = 39/108 (36%), Gaps = 31/108 (28%)

Query: 185  APAPLTPPPPPPPSRCLPQDEACADTGSGSAEGLA---------ADGPHLHTLTQPIVVT 235
            A A + PPPPPPP+   P         S     +A           G H+H+ T    + 
Sbjct: 1622 AAAVVPPPPPPPPA---PGPHLVQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLP 1678

Query: 236  VPRPPPRP-----PKSVPGRAVR--------------PEPPAPAPAAL 264
             P PPP P     P   P   ++              P PP P P+++
Sbjct: 1679 PPPPPPGPAPHHHPPPHPSTGLQGLQAQHQHVVNSAPPPPPPPPPSSV 1726



 Score = 33.5 bits (75), Expect = 0.24
 Identities = 28/93 (30%), Positives = 35/93 (37%), Gaps = 17/93 (18%)

Query: 187  APLTPPPPPPPSRCLPQDEACAD-------TGSGSAEGLAADGPHLHTLTQPIVVTVPRP 239
            AP  PPPPPP S      +  A+        GS S + +   GP+          TVP  
Sbjct: 1543 APPPPPPPPPSSSYYQNQQPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQTVPGH 1602

Query: 240  PPRPPKSVPGR----------AVRPEPPAPAPA 262
               P   +P +          AV P PP P PA
Sbjct: 1603 HVTPGHFLPSQNPTIHHQTAAAVVPPPPPPPPA 1635


>gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
            sapiens]
          Length = 1858

 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 67/228 (29%), Positives = 83/228 (36%), Gaps = 42/228 (18%)

Query: 45   PPAPPFPAAPGPWL-RRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAA---LARPSP 100
            PP PP P APGP L ++P    + S    V P  A    V   S +  Q A   L  P P
Sbjct: 1627 PPPPPPPPAPGPHLVQQPNSHQQHSVAHVVGPVHA----VTPGSHIHSQTAGHHLPPPPP 1682

Query: 101  RWGLALHRCSVTPSSRPAPGPALALLREGCPAD----TSVAFPPPPPPSPGAARPARFSF 156
              G A       P   P P P+  L  +G  A      + A PPPPPP P +   +    
Sbjct: 1683 PPGPA-------PHHHPPPHPSTGL--QGLQAQHQHVVNSAPPPPPPPPPSSVLASGH-- 1731

Query: 157  RLRPVFNASVQFLHCQLSRCRRLRGVRRAPAPLTPPPPPPPSRCLPQDEACADTGSGSAE 216
                    S Q LH         +G    P+   P  PP PS+           G G   
Sbjct: 1732 -----HTTSAQALHHPPH-----QGPPLFPSSAHPTVPPYPSQATHH----TTLGPGPQH 1777

Query: 217  GLAADGPHLHTLTQPIVVTVPRPPPRPPKSVPGRAVRPEPPAPAPAAL 264
              +  GPH      P+ VT P   P+ P S+P        P P   AL
Sbjct: 1778 QPSGTGPHC-----PLPVTGPHLQPQGPNSIPTPTASGFCPHPGSVAL 1820



 Score = 34.3 bits (77), Expect = 0.14
 Identities = 28/108 (25%), Positives = 39/108 (36%), Gaps = 31/108 (28%)

Query: 185  APAPLTPPPPPPPSRCLPQDEACADTGSGSAEGLA---------ADGPHLHTLTQPIVVT 235
            A A + PPPPPPP+   P         S     +A           G H+H+ T    + 
Sbjct: 1622 AAAVVPPPPPPPPA---PGPHLVQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLP 1678

Query: 236  VPRPPPRP-----PKSVPGRAVR--------------PEPPAPAPAAL 264
             P PPP P     P   P   ++              P PP P P+++
Sbjct: 1679 PPPPPPGPAPHHHPPPHPSTGLQGLQAQHQHVVNSAPPPPPPPPPSSV 1726



 Score = 33.5 bits (75), Expect = 0.24
 Identities = 28/93 (30%), Positives = 35/93 (37%), Gaps = 17/93 (18%)

Query: 187  APLTPPPPPPPSRCLPQDEACAD-------TGSGSAEGLAADGPHLHTLTQPIVVTVPRP 239
            AP  PPPPPP S      +  A+        GS S + +   GP+          TVP  
Sbjct: 1543 APPPPPPPPPSSSYYQNQQPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQTVPGH 1602

Query: 240  PPRPPKSVPGR----------AVRPEPPAPAPA 262
               P   +P +          AV P PP P PA
Sbjct: 1603 HVTPGHFLPSQNPTIHHQTAAAVVPPPPPPPPA 1635


>gi|85815829 SH3-domain binding protein 1 [Homo sapiens]
          Length = 701

 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 56/187 (29%), Positives = 71/187 (37%), Gaps = 32/187 (17%)

Query: 112 TPSSRPAPGPALA-----LLREGCPADTSVAFPPPPPPSPGAARPARFSFRLRPVFNASV 166
           TP++ PAP PA A      L      + + +  PP P SP   R         P   A V
Sbjct: 506 TPATTPAPAPAPAPAPAPALASAATKERTESEVPPRPASPKVTRSP-------PETAAPV 558

Query: 167 QFLHCQLSRCRRLRGVRRAPAPLTPPPP-------PPPSRCLPQDEACADTGSGSAEGLA 219
           +         RR +  R APA  T PPP        PP+  LP       T       L 
Sbjct: 559 E------DMARRTK--RPAPARPTMPPPQVSGSRSSPPAPPLPPGSGSPGTPQALPRRLV 610

Query: 220 ADGPHLHTLTQPIVVTVPRPPPRPPKSVPGRAVRPEPPAPAPAALEPAPVVALVLAAFVL 279
                  T+  P+  T P+P  R  +  P     P P +P PA+  P+PV     A   L
Sbjct: 611 GSSLRAPTVPPPLPPTPPQPARRQSRRSP---ASPSPASPGPAS--PSPVSLSNPAQVDL 665

Query: 280 GAALAAG 286
           GAA A G
Sbjct: 666 GAATAEG 672



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 64/227 (28%), Positives = 84/227 (37%), Gaps = 57/227 (25%)

Query: 41  PFPAPPAPPFPA-APGPWLRRPLFSLKLSDTEDVFPRRAGP--LEVPADSRVFVQ---AA 94
           P PA    P PA AP P       + K     +V PR A P     P ++   V+     
Sbjct: 505 PTPATTPAPAPAPAPAPAPALASAATKERTESEVPPRPASPKVTRSPPETAAPVEDMARR 564

Query: 95  LARPSP-RWGLALHRCSVTPSSRPAP---------GPALALLREGCPADTSV-AFPPPPP 143
             RP+P R  +   + S + SS PAP         G   AL R    +       PPP P
Sbjct: 565 TKRPAPARPTMPPPQVSGSRSSPPAPPLPPGSGSPGTPQALPRRLVGSSLRAPTVPPPLP 624

Query: 144 PSPGAARPARFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAPAPLTPPPPPP--PSRCL 201
           P+P   +PAR                          R  RR+PA  +P  P P  PS   
Sbjct: 625 PTP--PQPAR--------------------------RQSRRSPASPSPASPGPASPSPVS 656

Query: 202 PQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPPPRPPKSVP 248
             + A  D G+ +AEG A +           +  VP PP  PP+  P
Sbjct: 657 LSNPAQVDLGAATAEGGAPEA----------ISGVPTPPAIPPQPRP 693



 Score = 32.3 bits (72), Expect = 0.54
 Identities = 45/196 (22%), Positives = 59/196 (30%), Gaps = 56/196 (28%)

Query: 3   ESAAATASLFQRRRRGRGGRVTFPGGLKGSARFLSFGPPFPAPPAPPFPAAPGPWLRRPL 62
           E+AA    + +R +R    R T P      +R        PAPP PP   +PG       
Sbjct: 553 ETAAPVEDMARRTKRPAPARPTMPPPQVSGSRSSP-----PAPPLPPGSGSPG------- 600

Query: 63  FSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPSPRWGLALHRCSVTPSSRPAPGPA 122
                  T    PRR             V ++L  P           +V P   P P   
Sbjct: 601 -------TPQALPRR------------LVGSSLRAP-----------TVPPPLPPTPPQP 630

Query: 123 LALLREGCPADTSVAFPPPPPPSP-GAARPARFSFRLRPVFNASVQFLHCQLSRCRRLRG 181
                   PA  S A P P  PSP   + PA+           + +              
Sbjct: 631 ARRQSRRSPASPSPASPGPASPSPVSLSNPAQVDLGAATAEGGAPE-------------A 677

Query: 182 VRRAPAPLTPPPPPPP 197
           +   P P   PP P P
Sbjct: 678 ISGVPTPPAIPPQPRP 693


>gi|40353727 synaptopodin isoform A [Homo sapiens]
          Length = 903

 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 71/259 (27%), Positives = 84/259 (32%), Gaps = 56/259 (21%)

Query: 36  LSFGPPFPAPPAPPFPAAPGPWLRRPLFSLKLSDTED------VFPRRAGPLEVPADSRV 89
           L   P  P    PP PA P P    P   L  S  +D      V P   G +   + SR 
Sbjct: 596 LDLVPNLPKGALPPSPALPRPSRSSP--GLYTSPGQDSLQPTAVSPPYGGDISPVSPSRA 653

Query: 90  FVQAALARPSPRWGL------ALHRCSVTPSSRP----------------APGPALALLR 127
           +   A   P P +        A  R    P+S P                +PGP      
Sbjct: 654 WSPRAKQAPRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRPPSSLDGWVSPGPWEP--G 711

Query: 128 EGCPADTSVAFPPPPPPSPG----AARPARFSFRLRPVFNASVQFLHCQLSRCRRLRGVR 183
            G    +    PPPPP SP     +  P R     RP        L   +    R +   
Sbjct: 712 RGSSMSSPPPLPPPPPMSPSWSERSVSPLRPETEARPPSRQLQALLARNIINAARRKSAS 771

Query: 184 ---------------RAPAPLTPPPPPPPSRCLPQDEACADTGSGSAEGLA-ADGPHLHT 227
                          RAP P  PPPPPPP    PQ    A  GS +  G A A  P    
Sbjct: 772 PRSAGAENPRPFSPPRAPPPPPPPPPPPPRMRSPQP---ARPGSAAVPGAAFAPIPRSPL 828

Query: 228 LTQPIVVTVPRPP-PRPPK 245
              P   T PR P P PP+
Sbjct: 829 PAGPSSCTSPRSPLPAPPR 847



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 36/123 (29%), Positives = 41/123 (33%), Gaps = 24/123 (19%)

Query: 38  FGPPFPAPPAPPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALAR 97
           F PP  APP PP P  P P +R P             P R G   VP         A   
Sbjct: 783 FSPP-RAPPPPPPPPPPPPRMRSPQ------------PARPGSAAVPG--------AAFA 821

Query: 98  PSPRWGLALHRCSVTPSSRPAPGPALALLREGCPADTSVAFPPPPPPSPGAARPARFSFR 157
           P PR  L     S T    P P P    L    P D+ V+         GA  P    + 
Sbjct: 822 PIPRSPLPAGPSSCTSPRSPLPAPPRPFLYRRSPTDSDVSL---DSEDSGAKSPGILGYN 878

Query: 158 LRP 160
           + P
Sbjct: 879 ICP 881


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 1124

 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 86/325 (26%), Positives = 103/325 (31%), Gaps = 82/325 (25%)

Query: 40   PPFPAPP---APPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFV-QAAL 95
            PP  APP   APP    P P    P+        +   P  A PL+VP         +  
Sbjct: 691  PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPS 750

Query: 96   ARPSPRWGLALHRCSV-TPSSRPAPGPALALLREGCPADTSVAFPPPPP-PSPGAARPAR 153
            A P PR    L    +  P S PA  P   L +    A  ++A PP    PSP A+ P +
Sbjct: 751  ATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQ 810

Query: 154  FSF----------------RLRPVFNASVQFLHCQLSRCRRLRGVRRAPAP--------- 188
              F                +  PV  A +  +         L+  RR P P         
Sbjct: 811  APFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGP 870

Query: 189  -----LTPPPPPPPSR-----------------CLPQDEACADTGSGSAEGLAADGP--- 223
                 L P PPPPPSR                      E      SG   G AA  P   
Sbjct: 871  RLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDA 930

Query: 224  HLHTLTQPIVVTVPRPP-----------PRPPKSVPGRA---------VRPEPPAPAPAA 263
             L           P PP           P PP + PG A           PE   PAP A
Sbjct: 931  ELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGA 990

Query: 264  LEPAPVVALVLAAFVLGAALAAGLG 288
            L+P P      +    G   AAG G
Sbjct: 991  LDPGP------SPGTSGGKAAAGAG 1009



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 65/240 (27%), Positives = 85/240 (35%), Gaps = 36/240 (15%)

Query: 40  PPFPAPPA---PPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAA-L 95
           PP  APPA   PP    P P    PL  L     +        PL+ P         + L
Sbjct: 590 PPPQAPPALASPPLQGLPSP----PLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPL 645

Query: 96  ARPSPRW--GLALHRCSVTPSSRPAPGPALALLREGCPADTSVAFPPPPPPSPGAARPAR 153
           A PSP+    LA+H      S  P+P           P  +  A PP   P   AA P  
Sbjct: 646 ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPP-- 703

Query: 154 FSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAPAPLTPPPPPPPSRCLPQDEACADTGSG 213
              ++ P   AS                   +P+   PP  PPP    P     +   S 
Sbjct: 704 --LQVPPSPPASPPM----------------SPSATPPPQAPPPLAAPPLQVPPSPPASP 745

Query: 214 SAEGLAADGPHLHTLTQPIVVTVP-RPPPRPPKSVPGRAVRPEPPAPAPAALEPAPVVAL 272
                A   P +     P++   P + PP PP S+P  +   +PP  AP AL   P+ AL
Sbjct: 746 PMSPSATPPPRV----PPLLAAPPLQVPPSPPASLP-MSPLAKPPPQAPPALATPPLQAL 800



 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 66/228 (28%), Positives = 81/228 (35%), Gaps = 58/228 (25%)

Query: 43  PAPPAPPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPSPRW 102
           P+P A   P+A G   R    SL  S T    P R+GP    A       A  ++P P+ 
Sbjct: 220 PSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGP---SARGTPRAPAHPSQPKPKG 276

Query: 103 GLALHRCSVTPSSRPAPGPALALLREGCPADTSVAFPPPPPPSPGAARPARFSFRLRPVF 162
             AL    VTP  + A  PAL  L    P  T       P PS   ARP      + P  
Sbjct: 277 LQALRPPQVTPPRKDA-APALGPLSSS-PLAT-------PSPSGTKARP------VPPPD 321

Query: 163 NASVQFLHCQLSRCRRLRGVRRAPAPLTPPPPPPPSRCLPQDEACADTGSGSAEGLAADG 222
           NA+                    P P T PP PP +  LP               LA   
Sbjct: 322 NAAT-------------------PLPATLPPSPPLATPLP---------------LAPPS 347

Query: 223 PHLHTLTQPIVVTVPRPPPRPPKSVPGRAVRPEPPAPAPAALEPAPVV 270
           P       P + T+P PP  PP   P       PP  AP +L+  P +
Sbjct: 348 PS----APPSLQTLPSPPATPPSQAPPSMT--TPPMQAPPSLQTIPPI 389



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 68/247 (27%), Positives = 87/247 (35%), Gaps = 35/247 (14%)

Query: 43  PAPPAPPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPSPRW 102
           P+   PP   A  P L  P                  PL  P        +++A P P+ 
Sbjct: 539 PSLAPPPLQTASAP-LTTPHLETPPCPAPCPLQAPPSPLTTPPPE---TPSSIATPPPQA 594

Query: 103 GLALHRCSVTPSSRPAPGPALALLREGCP-ADTSVAFPP-PPPPSPGAARPARFSFRLRP 160
             AL     +P  +  P P L+ L    P A   +A PP   PPSP A+ P      L P
Sbjct: 595 PPAL----ASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPP------LSP 644

Query: 161 VFNASVQFLHCQLSRCRRLRGVRRAPAPLTPPPPPPPSR-----CLPQDEACADTGSGSA 215
           +   S Q              V    AP +PPP PP          P     A   S + 
Sbjct: 645 LATPSPQ--------APNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAP 696

Query: 216 EGLAADG---PHLHTLTQPIVVTVPRPPPRPPK-SVPGRAVRPEPPA--PAPAALEPAPV 269
             LAA     P     + P+  +   PP  PP  + P   V P PPA  P   +  P P 
Sbjct: 697 PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPR 756

Query: 270 VALVLAA 276
           V  +LAA
Sbjct: 757 VPPLLAA 763



 Score = 34.7 bits (78), Expect = 0.11
 Identities = 58/240 (24%), Positives = 79/240 (32%), Gaps = 36/240 (15%)

Query: 40  PPFPAPPA----PPFP---AAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQ 92
           PP  APP+    PP     +   P L+ P   L LS  +      +  L+          
Sbjct: 375 PPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATH------- 427

Query: 93  AALARPSPRWGLALHRCSVTPSSRPAPGPALALLREGCPADTSVAFPPPPPPSPG---AA 149
            +    SPR   A    S+T  SRPA  P      +  P    ++ P  PP       A 
Sbjct: 428 -SFLTMSPRQTQA----SLTSPSRPASTPP-----DSPPLQAPLSLPASPPLQTSLSPAV 477

Query: 150 RPARFSFRLRPVFNASVQFLHC-QLSRCRRLRGVRRAPAPLTPPP--PPPPSRCLPQDEA 206
            P      + P+   S    H  Q      +       + L PP    PP S   P  E 
Sbjct: 478 SPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLEN 537

Query: 207 CADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPPPRPPKSVPGRAVRPEPPAPAPAALEP 266
                    +  +A       LT P + T P P P P ++ P     P P  P+  A  P
Sbjct: 538 LPSLAPPPLQTASAP------LTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPP 591


>gi|14602439 Williams Beuren syndrome chromosome region 14 isoform
           delta [Homo sapiens]
          Length = 831

 Score = 52.0 bits (123), Expect = 7e-07
 Identities = 78/259 (30%), Positives = 95/259 (36%), Gaps = 47/259 (18%)

Query: 22  RVTFPGGLKGSARFLSFGPPFPAPPAP--PFPAAPGPWLRRPLFSLKLSDTEDV----FP 75
           R + PG L  SA FLS     P  P P  P P  P P L  P    K+   E      FP
Sbjct: 359 RNSCPGPLDSSA-FLSSDFLLPEDPKPRLPPPPVPPPLLHYPP-PAKVPGLEPCPPPPFP 416

Query: 76  RRAGPLEVPADSRVFVQAALARPSPRWGLALHRCSVTPSSRPAPGPALALLREGCPADTS 135
             A P  +  +  +F        SPR+          P+  PAPG +        P    
Sbjct: 417 PMAPPTALLQEEPLF--------SPRFPF--------PTVPPAPGVS--------PLPAP 452

Query: 136 VAFPPPPPPSPGAARPARFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAPAPLTPPPPP 195
            AFPP P   P  A P  F   L P+  +   F  C        RG   AP+P      P
Sbjct: 453 AAFPPTPQSVPSPA-PTPFPIELLPLGYSEPAFGPC----FSMPRGKPPAPSPRGQKASP 507

Query: 196 PPSRCLPQDEACADTGSGS-----AEGLAADGPHLHTLTQPIVV-TVPRPPPRPPKSVPG 249
           P    L    A   T +GS      + L A  P    L  P+V  T+ R P  P ++VP 
Sbjct: 508 PT---LAPATASPPTTAGSNNPCLTQLLTAAKPE-QALEPPLVSSTLLRSPGSPQETVPE 563

Query: 250 RAVRPEPPAPAPAALEPAP 268
                 PP PAP    P P
Sbjct: 564 FPCTFLPPTPAPTPPRPPP 582



 Score = 37.4 bits (85), Expect = 0.017
 Identities = 57/233 (24%), Positives = 74/233 (31%), Gaps = 36/233 (15%)

Query: 41  PFPAPPAPPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPSP 100
           P P PP PP           PLFS +             PL  PA    F     + PSP
Sbjct: 409 PCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPA---AFPPTPQSVPSP 465

Query: 101 RWGLALHRCSVTPSSRPAPGPALALLREGCPADTSVAFPPPPPP-SPGAARPARFSFRLR 159
                         S PA GP  ++ R   PA +       PP  +P  A P   +    
Sbjct: 466 APTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNN 525

Query: 160 PVFNASV------QFLHCQLSRCRRLRG---------------VRRAPAPLTPPPPPPPS 198
           P     +      Q L   L     LR                +   PAP  P PPP P+
Sbjct: 526 PCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPA 585

Query: 199 RCLPQ--------DEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPPPRP 243
              P         +       SGS   L+ D   L ++  P  ++V   PP+P
Sbjct: 586 TLAPSRPLLVPKAERLSPPAPSGSERRLSGD---LSSMPGPGTLSVRVSPPQP 635


>gi|14602437 Williams Beuren syndrome chromosome region 14 isoform
           gamma [Homo sapiens]
          Length = 850

 Score = 52.0 bits (123), Expect = 7e-07
 Identities = 78/259 (30%), Positives = 95/259 (36%), Gaps = 47/259 (18%)

Query: 22  RVTFPGGLKGSARFLSFGPPFPAPPAP--PFPAAPGPWLRRPLFSLKLSDTEDV----FP 75
           R + PG L  SA FLS     P  P P  P P  P P L  P    K+   E      FP
Sbjct: 359 RNSCPGPLDSSA-FLSSDFLLPEDPKPRLPPPPVPPPLLHYPP-PAKVPGLEPCPPPPFP 416

Query: 76  RRAGPLEVPADSRVFVQAALARPSPRWGLALHRCSVTPSSRPAPGPALALLREGCPADTS 135
             A P  +  +  +F        SPR+          P+  PAPG +        P    
Sbjct: 417 PMAPPTALLQEEPLF--------SPRFPF--------PTVPPAPGVS--------PLPAP 452

Query: 136 VAFPPPPPPSPGAARPARFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAPAPLTPPPPP 195
            AFPP P   P  A P  F   L P+  +   F  C        RG   AP+P      P
Sbjct: 453 AAFPPTPQSVPSPA-PTPFPIELLPLGYSEPAFGPC----FSMPRGKPPAPSPRGQKASP 507

Query: 196 PPSRCLPQDEACADTGSGS-----AEGLAADGPHLHTLTQPIVV-TVPRPPPRPPKSVPG 249
           P    L    A   T +GS      + L A  P    L  P+V  T+ R P  P ++VP 
Sbjct: 508 PT---LAPATASPPTTAGSNNPCLTQLLTAAKPE-QALEPPLVSSTLLRSPGSPQETVPE 563

Query: 250 RAVRPEPPAPAPAALEPAP 268
                 PP PAP    P P
Sbjct: 564 FPCTFLPPTPAPTPPRPPP 582



 Score = 37.4 bits (85), Expect = 0.017
 Identities = 57/233 (24%), Positives = 74/233 (31%), Gaps = 36/233 (15%)

Query: 41  PFPAPPAPPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPSP 100
           P P PP PP           PLFS +             PL  PA    F     + PSP
Sbjct: 409 PCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPA---AFPPTPQSVPSP 465

Query: 101 RWGLALHRCSVTPSSRPAPGPALALLREGCPADTSVAFPPPPPP-SPGAARPARFSFRLR 159
                         S PA GP  ++ R   PA +       PP  +P  A P   +    
Sbjct: 466 APTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNN 525

Query: 160 PVFNASV------QFLHCQLSRCRRLRG---------------VRRAPAPLTPPPPPPPS 198
           P     +      Q L   L     LR                +   PAP  P PPP P+
Sbjct: 526 PCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPA 585

Query: 199 RCLPQ--------DEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPPPRP 243
              P         +       SGS   L+ D   L ++  P  ++V   PP+P
Sbjct: 586 TLAPSRPLLVPKAERLSPPAPSGSERRLSGD---LSSMPGPGTLSVRVSPPQP 635


>gi|14602435 Williams Beuren syndrome chromosome region 14 isoform
           beta [Homo sapiens]
          Length = 833

 Score = 52.0 bits (123), Expect = 7e-07
 Identities = 78/259 (30%), Positives = 95/259 (36%), Gaps = 47/259 (18%)

Query: 22  RVTFPGGLKGSARFLSFGPPFPAPPAP--PFPAAPGPWLRRPLFSLKLSDTEDV----FP 75
           R + PG L  SA FLS     P  P P  P P  P P L  P    K+   E      FP
Sbjct: 359 RNSCPGPLDSSA-FLSSDFLLPEDPKPRLPPPPVPPPLLHYPP-PAKVPGLEPCPPPPFP 416

Query: 76  RRAGPLEVPADSRVFVQAALARPSPRWGLALHRCSVTPSSRPAPGPALALLREGCPADTS 135
             A P  +  +  +F        SPR+          P+  PAPG +        P    
Sbjct: 417 PMAPPTALLQEEPLF--------SPRFPF--------PTVPPAPGVS--------PLPAP 452

Query: 136 VAFPPPPPPSPGAARPARFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAPAPLTPPPPP 195
            AFPP P   P  A P  F   L P+  +   F  C        RG   AP+P      P
Sbjct: 453 AAFPPTPQSVPSPA-PTPFPIELLPLGYSEPAFGPC----FSMPRGKPPAPSPRGQKASP 507

Query: 196 PPSRCLPQDEACADTGSGS-----AEGLAADGPHLHTLTQPIVV-TVPRPPPRPPKSVPG 249
           P    L    A   T +GS      + L A  P    L  P+V  T+ R P  P ++VP 
Sbjct: 508 PT---LAPATASPPTTAGSNNPCLTQLLTAAKPE-QALEPPLVSSTLLRSPGSPQETVPE 563

Query: 250 RAVRPEPPAPAPAALEPAP 268
                 PP PAP    P P
Sbjct: 564 FPCTFLPPTPAPTPPRPPP 582



 Score = 37.4 bits (85), Expect = 0.017
 Identities = 57/233 (24%), Positives = 74/233 (31%), Gaps = 36/233 (15%)

Query: 41  PFPAPPAPPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPSP 100
           P P PP PP           PLFS +             PL  PA    F     + PSP
Sbjct: 409 PCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPA---AFPPTPQSVPSP 465

Query: 101 RWGLALHRCSVTPSSRPAPGPALALLREGCPADTSVAFPPPPPP-SPGAARPARFSFRLR 159
                         S PA GP  ++ R   PA +       PP  +P  A P   +    
Sbjct: 466 APTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNN 525

Query: 160 PVFNASV------QFLHCQLSRCRRLRG---------------VRRAPAPLTPPPPPPPS 198
           P     +      Q L   L     LR                +   PAP  P PPP P+
Sbjct: 526 PCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPA 585

Query: 199 RCLPQ--------DEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPPPRP 243
              P         +       SGS   L+ D   L ++  P  ++V   PP+P
Sbjct: 586 TLAPSRPLLVPKAERLSPPAPSGSERRLSGD---LSSMPGPGTLSVRVSPPQP 635


>gi|14602433 Williams Beuren syndrome chromosome region 14 isoform
           alpha [Homo sapiens]
          Length = 852

 Score = 52.0 bits (123), Expect = 7e-07
 Identities = 78/259 (30%), Positives = 95/259 (36%), Gaps = 47/259 (18%)

Query: 22  RVTFPGGLKGSARFLSFGPPFPAPPAP--PFPAAPGPWLRRPLFSLKLSDTEDV----FP 75
           R + PG L  SA FLS     P  P P  P P  P P L  P    K+   E      FP
Sbjct: 359 RNSCPGPLDSSA-FLSSDFLLPEDPKPRLPPPPVPPPLLHYPP-PAKVPGLEPCPPPPFP 416

Query: 76  RRAGPLEVPADSRVFVQAALARPSPRWGLALHRCSVTPSSRPAPGPALALLREGCPADTS 135
             A P  +  +  +F        SPR+          P+  PAPG +        P    
Sbjct: 417 PMAPPTALLQEEPLF--------SPRFPF--------PTVPPAPGVS--------PLPAP 452

Query: 136 VAFPPPPPPSPGAARPARFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAPAPLTPPPPP 195
            AFPP P   P  A P  F   L P+  +   F  C        RG   AP+P      P
Sbjct: 453 AAFPPTPQSVPSPA-PTPFPIELLPLGYSEPAFGPC----FSMPRGKPPAPSPRGQKASP 507

Query: 196 PPSRCLPQDEACADTGSGS-----AEGLAADGPHLHTLTQPIVV-TVPRPPPRPPKSVPG 249
           P    L    A   T +GS      + L A  P    L  P+V  T+ R P  P ++VP 
Sbjct: 508 PT---LAPATASPPTTAGSNNPCLTQLLTAAKPE-QALEPPLVSSTLLRSPGSPQETVPE 563

Query: 250 RAVRPEPPAPAPAALEPAP 268
                 PP PAP    P P
Sbjct: 564 FPCTFLPPTPAPTPPRPPP 582



 Score = 37.4 bits (85), Expect = 0.017
 Identities = 57/233 (24%), Positives = 74/233 (31%), Gaps = 36/233 (15%)

Query: 41  PFPAPPAPPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPSP 100
           P P PP PP           PLFS +             PL  PA    F     + PSP
Sbjct: 409 PCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPA---AFPPTPQSVPSP 465

Query: 101 RWGLALHRCSVTPSSRPAPGPALALLREGCPADTSVAFPPPPPP-SPGAARPARFSFRLR 159
                         S PA GP  ++ R   PA +       PP  +P  A P   +    
Sbjct: 466 APTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNN 525

Query: 160 PVFNASV------QFLHCQLSRCRRLRG---------------VRRAPAPLTPPPPPPPS 198
           P     +      Q L   L     LR                +   PAP  P PPP P+
Sbjct: 526 PCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPA 585

Query: 199 RCLPQ--------DEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPPPRP 243
              P         +       SGS   L+ D   L ++  P  ++V   PP+P
Sbjct: 586 TLAPSRPLLVPKAERLSPPAPSGSERRLSGD---LSSMPGPGTLSVRVSPPQP 635


>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
          Length = 538

 Score = 52.0 bits (123), Expect = 7e-07
 Identities = 60/218 (27%), Positives = 78/218 (35%), Gaps = 43/218 (19%)

Query: 88  RVFVQAALARPSPRWGLALHRCS-VTPSSRPAPGPALALLREGCPADTSVAFPPP----- 141
           ++  Q A+ R S +  ++    + V P  R A  PA      G PA  + A PPP     
Sbjct: 75  KLIQQRAVLRVSYKGSISYRNAARVQPPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPP 134

Query: 142 PPPSP-GAARPARFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAPAPLTPPPPPPPSRC 200
           PPP+P  AA PA                           R  R A A  T PP P P++ 
Sbjct: 135 PPPAPVAAAAPA---------------------------RAPRAAAAAATAPPSPGPAQP 167

Query: 201 LPQDEACADTGS---GSAEGLAADGPHLHTLTQPIVVTVPRPPPRPPKSVPGRAVRPEPP 257
            P+ +  A   +     A   A   P       P  V    PP  PP   P    + +PP
Sbjct: 168 GPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPP 227

Query: 258 APAPAALEPAPVVALVLAAFVLGAALAAGLGLVCAHSG 295
            P P   +P P    V A    GAA    L  V  + G
Sbjct: 228 PPQP---QPPPEGGAVRAG---GAARPVSLREVVRYLG 259



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 35/109 (32%), Positives = 41/109 (37%), Gaps = 17/109 (15%)

Query: 40  PPFPAPPAPPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPS 99
           PP PAPP PP P A     R P    + +      P   GP +     R    A LA P 
Sbjct: 128 PPTPAPPPPPAPVAAAAPARAP----RAAAAAATAPPSPGPAQ--PGPRAQRAAPLAAPP 181

Query: 100 PRWGLALHRCSVTPSSRPAPGPALALLREGCPADTSVAFPPPPPPSPGA 148
           P            P++ PA  P     R   PA  +   P PPPP P A
Sbjct: 182 P-----------APAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPA 219


>gi|60460889 Myb protein P42POP [Homo sapiens]
          Length = 399

 Score = 51.6 bits (122), Expect = 9e-07
 Identities = 74/263 (28%), Positives = 89/263 (33%), Gaps = 68/263 (25%)

Query: 45  PPAPPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPSPRWGL 104
           PPA P    P P      + L     ED   RRA       D+    +A  + P P W  
Sbjct: 136 PPAAPSSQPPPPSACPQRYVLSEDRRED---RRA-------DTSAHSKAGSSSPEP-WA- 183

Query: 105 ALHRCSVTPSSRPAPGPALALLREGCPADT--SVAFP----PPPPPSPGAARPARFSFRL 158
              R S TP     P P     RE  P      V  P     PPPP+P    P   +   
Sbjct: 184 ---RPSCTPQEGGCPRPKE---RESPPPSALQPVQLPRLALSPPPPAPPLPPPPPLA--- 234

Query: 159 RPVFNASVQFLHCQLSRCRRLRGVRRAPAPLTPPPPPPPSRCLPQDEACADTGSGSAEGL 218
                                   + AP+P +PPPPP P   L   +   D      E  
Sbjct: 235 ------------------------QVAPSPPSPPPPPRPPPTLSASDPSLDFLRAQQETA 270

Query: 219 AADGPHLHTLTQ-------------PIVVTVP---RPPPRPPKSVPGRAVRPEPPAPAPA 262
            A      TL Q             P++   P    PPP PP   P    RP  P PAP 
Sbjct: 271 NAIRELAGTLRQGLAKLSEALSALLPLLPGTPVDSLPPPLPPPPPPPPPPRPVLPPPAP- 329

Query: 263 ALEPAPVVALVLAAFVLGAALAA 285
            +E  P    V+AA V GA +AA
Sbjct: 330 KVEITPEPVSVVAAVVDGAVVAA 352



 Score = 41.6 bits (96), Expect = 9e-04
 Identities = 44/181 (24%), Positives = 60/181 (33%), Gaps = 48/181 (26%)

Query: 98  PSPRWGLALHRCSVTPSSRPAPGPALALLREGCPADTSVAFPPPPPPSPGAARPARFSFR 157
           PS    + L R +++P     P P    L +  P+  S   PP PPP+  A+ P      
Sbjct: 205 PSALQPVQLPRLALSPPPPAPPLPPPPPLAQVAPSPPSPPPPPRPPPTLSASDP------ 258

Query: 158 LRPVFNASVQFLHCQ---LSRCRRLRGVRR--------------------------APAP 188
                  S+ FL  Q    +  R L G  R                           P P
Sbjct: 259 -------SLDFLRAQQETANAIRELAGTLRQGLAKLSEALSALLPLLPGTPVDSLPPPLP 311

Query: 189 LTPPPPPPPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVVT------VPRPPPR 242
             PPPPPPP   LP      +        +AA         + +++        PRPPP 
Sbjct: 312 PPPPPPPPPRPVLPPPAPKVEITPEPVSVVAAVVDGAVVAARGVIIAPRSEEGAPRPPPA 371

Query: 243 P 243
           P
Sbjct: 372 P 372



 Score = 38.5 bits (88), Expect = 0.008
 Identities = 40/153 (26%), Positives = 52/153 (33%), Gaps = 19/153 (12%)

Query: 120 GPALALLREGCPADTSVAFPPPPPPSPGAARPARFSFRLRPVFNASVQFLHCQLSRCRRL 179
           GP +A    G  A+   A P   PP P A  P R+              L       RR 
Sbjct: 121 GPGVAAPGAGAGAEEPPAAPSSQPPPPSAC-PQRY-------------VLSEDRREDRRA 166

Query: 180 RGVRRAPAPLTPPPPPPPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRP 239
                + A  + P P     C PQ+  C       +   +A    L  +  P +   P P
Sbjct: 167 DTSAHSKAGSSSPEPWARPSCTPQEGGCPRPKERESPPPSA----LQPVQLPRLALSPPP 222

Query: 240 PPRP-PKSVPGRAVRPEPPAPAPAALEPAPVVA 271
           P  P P   P   V P PP+P P    P  + A
Sbjct: 223 PAPPLPPPPPLAQVAPSPPSPPPPPRPPPTLSA 255



 Score = 37.0 bits (84), Expect = 0.022
 Identities = 51/177 (28%), Positives = 63/177 (35%), Gaps = 23/177 (12%)

Query: 36  LSFGPPFPAPPAPPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGP-LEVPADSRVFVQAA 94
           L+  PP PAPP PP P         PL  +  S      P R  P L     S  F++A 
Sbjct: 216 LALSPPPPAPPLPPPP---------PLAQVAPSPPSPPPPPRPPPTLSASDPSLDFLRAQ 266

Query: 95  LARPSPRWGLA-LHRCSVTPSSRPAPGPALALLREGCPADTSVAFPPPPPPSPGAARPA- 152
               +    LA   R  +   S      AL  L  G P D+     PPPPP P   RP  
Sbjct: 267 QETANAIRELAGTLRQGLAKLSEAL--SALLPLLPGTPVDSLPPPLPPPPPPPPPPRPVL 324

Query: 153 -----RFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAPAPLTPPPPPPPSRCLPQD 204
                +      PV   +       ++     RGV  AP      P PPP+   P D
Sbjct: 325 PPPAPKVEITPEPVSVVAAVVDGAVVA----ARGVIIAPRSEEGAPRPPPAPLPPHD 377


>gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 48/170 (28%), Positives = 60/170 (35%), Gaps = 36/170 (21%)

Query: 111 VTPSSRPAPGPALALLREGCPADTSVAFPPPPPPSPGAARPARFSFRLRPVFNASVQFLH 170
           V+P+  P P P  + L       +  + PPPP P P             P   A +Q   
Sbjct: 320 VSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAP 379

Query: 171 CQLSRCRRLRGVRRAPAPLTPP---PPPPPSRCLPQDEACADTGSGSAEGLAADGPHLHT 227
             L           AP P+ PP   P PP +R  P  E                   +H 
Sbjct: 380 GVL---------HPAPPPIAPPLVQPSPPVARAAPVCETVP----------------VHP 414

Query: 228 LTQPIVVTVPRPPPRPPKSVPGRAVRPEPP------APAPAALEPAPVVA 271
           L Q  V  +P PPP PP   PG  +RP  P      A  P+ L P P  A
Sbjct: 415 LPQGEVQGLPPPPPPPPLPPPG--IRPSSPVTVTALAHPPSGLHPTPSTA 462



 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 44/138 (31%), Positives = 55/138 (39%), Gaps = 19/138 (13%)

Query: 139 PPPPPPSPGA--ARPARFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAP---APLTPPP 193
           PPPPPP  GA  A+P        P   +S   L   +    +     R P   +P  PPP
Sbjct: 278 PPPPPPMHGAGDAKPI-------PTCISSATGL---IENRPQSPATGRTPVFVSPTPPPP 327

Query: 194 PPPPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPPPRPPKSVPGRAVR 253
           PPP    L      A   S     +    P   T  Q   V    PPP P +  PG  + 
Sbjct: 328 PPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVP---PPPAPLQIAPG-VLH 383

Query: 254 PEPPAPAPAALEPAPVVA 271
           P PP  AP  ++P+P VA
Sbjct: 384 PAPPPIAPPLVQPSPPVA 401



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 48/167 (28%), Positives = 60/167 (35%), Gaps = 34/167 (20%)

Query: 40  PPFPAPPAPPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPS 99
           PP P PP PP  A   P +  P   L+++      P    P   P      +   L +PS
Sbjct: 350 PPVPPPPPPPATALQAPAVPPPPAPLQIA------PGVLHPAPPP------IAPPLVQPS 397

Query: 100 PRWGLALHRCSVTPSSRPAPGPALALLREGCPADTSVAFPPPPPPSPGAARPARFSFRLR 159
           P    A   C   P   P P   +    +G P       PPPPPP P           +R
Sbjct: 398 PPVARAAPVCETVP-VHPLPQGEV----QGLPP------PPPPPPLPPPG--------IR 438

Query: 160 PVFNASVQFLHCQLSRCRRLRGVRRAPAPLTP-PPPPPPSRCLPQDE 205
           P    +V  L    S          AP P  P  PP PPS+ +P  E
Sbjct: 439 PSSPVTVTALAHPPSGLHPTPST--APGPHVPLMPPSPPSQVIPASE 483



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 38/113 (33%), Positives = 41/113 (36%), Gaps = 20/113 (17%)

Query: 188 PLTPPPPPPPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPPPRPP--- 244
           P  PPPPPP       D     T   SA GL  + P      +  V   P PPP PP   
Sbjct: 275 PHEPPPPPPMHGA--GDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLP 332

Query: 245 ------------KSVPGRAVRPEPPAPAPAALEPA---PVVALVLAAFVLGAA 282
                        S P   V P PP PA A   PA   P   L +A  VL  A
Sbjct: 333 SALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPA 385


>gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 48/170 (28%), Positives = 60/170 (35%), Gaps = 36/170 (21%)

Query: 111 VTPSSRPAPGPALALLREGCPADTSVAFPPPPPPSPGAARPARFSFRLRPVFNASVQFLH 170
           V+P+  P P P  + L       +  + PPPP P P             P   A +Q   
Sbjct: 320 VSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAP 379

Query: 171 CQLSRCRRLRGVRRAPAPLTPP---PPPPPSRCLPQDEACADTGSGSAEGLAADGPHLHT 227
             L           AP P+ PP   P PP +R  P  E                   +H 
Sbjct: 380 GVL---------HPAPPPIAPPLVQPSPPVARAAPVCETVP----------------VHP 414

Query: 228 LTQPIVVTVPRPPPRPPKSVPGRAVRPEPP------APAPAALEPAPVVA 271
           L Q  V  +P PPP PP   PG  +RP  P      A  P+ L P P  A
Sbjct: 415 LPQGEVQGLPPPPPPPPLPPPG--IRPSSPVTVTALAHPPSGLHPTPSTA 462



 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 44/138 (31%), Positives = 55/138 (39%), Gaps = 19/138 (13%)

Query: 139 PPPPPPSPGA--ARPARFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAP---APLTPPP 193
           PPPPPP  GA  A+P        P   +S   L   +    +     R P   +P  PPP
Sbjct: 278 PPPPPPMHGAGDAKPI-------PTCISSATGL---IENRPQSPATGRTPVFVSPTPPPP 327

Query: 194 PPPPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPPPRPPKSVPGRAVR 253
           PPP    L      A   S     +    P   T  Q   V    PPP P +  PG  + 
Sbjct: 328 PPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVP---PPPAPLQIAPG-VLH 383

Query: 254 PEPPAPAPAALEPAPVVA 271
           P PP  AP  ++P+P VA
Sbjct: 384 PAPPPIAPPLVQPSPPVA 401



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 48/167 (28%), Positives = 60/167 (35%), Gaps = 34/167 (20%)

Query: 40  PPFPAPPAPPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPS 99
           PP P PP PP  A   P +  P   L+++      P    P   P      +   L +PS
Sbjct: 350 PPVPPPPPPPATALQAPAVPPPPAPLQIA------PGVLHPAPPP------IAPPLVQPS 397

Query: 100 PRWGLALHRCSVTPSSRPAPGPALALLREGCPADTSVAFPPPPPPSPGAARPARFSFRLR 159
           P    A   C   P   P P   +    +G P       PPPPPP P           +R
Sbjct: 398 PPVARAAPVCETVP-VHPLPQGEV----QGLPP------PPPPPPLPPPG--------IR 438

Query: 160 PVFNASVQFLHCQLSRCRRLRGVRRAPAPLTP-PPPPPPSRCLPQDE 205
           P    +V  L    S          AP P  P  PP PPS+ +P  E
Sbjct: 439 PSSPVTVTALAHPPSGLHPTPST--APGPHVPLMPPSPPSQVIPASE 483



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 38/113 (33%), Positives = 41/113 (36%), Gaps = 20/113 (17%)

Query: 188 PLTPPPPPPPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPPPRPP--- 244
           P  PPPPPP       D     T   SA GL  + P      +  V   P PPP PP   
Sbjct: 275 PHEPPPPPPMHGA--GDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLP 332

Query: 245 ------------KSVPGRAVRPEPPAPAPAALEPA---PVVALVLAAFVLGAA 282
                        S P   V P PP PA A   PA   P   L +A  VL  A
Sbjct: 333 SALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPA 385


>gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 48/170 (28%), Positives = 60/170 (35%), Gaps = 36/170 (21%)

Query: 111 VTPSSRPAPGPALALLREGCPADTSVAFPPPPPPSPGAARPARFSFRLRPVFNASVQFLH 170
           V+P+  P P P  + L       +  + PPPP P P             P   A +Q   
Sbjct: 320 VSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAP 379

Query: 171 CQLSRCRRLRGVRRAPAPLTPP---PPPPPSRCLPQDEACADTGSGSAEGLAADGPHLHT 227
             L           AP P+ PP   P PP +R  P  E                   +H 
Sbjct: 380 GVL---------HPAPPPIAPPLVQPSPPVARAAPVCETVP----------------VHP 414

Query: 228 LTQPIVVTVPRPPPRPPKSVPGRAVRPEPP------APAPAALEPAPVVA 271
           L Q  V  +P PPP PP   PG  +RP  P      A  P+ L P P  A
Sbjct: 415 LPQGEVQGLPPPPPPPPLPPPG--IRPSSPVTVTALAHPPSGLHPTPSTA 462



 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 44/138 (31%), Positives = 55/138 (39%), Gaps = 19/138 (13%)

Query: 139 PPPPPPSPGA--ARPARFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAP---APLTPPP 193
           PPPPPP  GA  A+P        P   +S   L   +    +     R P   +P  PPP
Sbjct: 278 PPPPPPMHGAGDAKPI-------PTCISSATGL---IENRPQSPATGRTPVFVSPTPPPP 327

Query: 194 PPPPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPPPRPPKSVPGRAVR 253
           PPP    L      A   S     +    P   T  Q   V    PPP P +  PG  + 
Sbjct: 328 PPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVP---PPPAPLQIAPG-VLH 383

Query: 254 PEPPAPAPAALEPAPVVA 271
           P PP  AP  ++P+P VA
Sbjct: 384 PAPPPIAPPLVQPSPPVA 401



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 48/167 (28%), Positives = 60/167 (35%), Gaps = 34/167 (20%)

Query: 40  PPFPAPPAPPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPS 99
           PP P PP PP  A   P +  P   L+++      P    P   P      +   L +PS
Sbjct: 350 PPVPPPPPPPATALQAPAVPPPPAPLQIA------PGVLHPAPPP------IAPPLVQPS 397

Query: 100 PRWGLALHRCSVTPSSRPAPGPALALLREGCPADTSVAFPPPPPPSPGAARPARFSFRLR 159
           P    A   C   P   P P   +    +G P       PPPPPP P           +R
Sbjct: 398 PPVARAAPVCETVP-VHPLPQGEV----QGLPP------PPPPPPLPPPG--------IR 438

Query: 160 PVFNASVQFLHCQLSRCRRLRGVRRAPAPLTP-PPPPPPSRCLPQDE 205
           P    +V  L    S          AP P  P  PP PPS+ +P  E
Sbjct: 439 PSSPVTVTALAHPPSGLHPTPST--APGPHVPLMPPSPPSQVIPASE 483



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 38/113 (33%), Positives = 41/113 (36%), Gaps = 20/113 (17%)

Query: 188 PLTPPPPPPPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPPPRPP--- 244
           P  PPPPPP       D     T   SA GL  + P      +  V   P PPP PP   
Sbjct: 275 PHEPPPPPPMHGA--GDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLP 332

Query: 245 ------------KSVPGRAVRPEPPAPAPAALEPA---PVVALVLAAFVLGAA 282
                        S P   V P PP PA A   PA   P   L +A  VL  A
Sbjct: 333 SALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPA 385


>gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 48/170 (28%), Positives = 60/170 (35%), Gaps = 36/170 (21%)

Query: 111 VTPSSRPAPGPALALLREGCPADTSVAFPPPPPPSPGAARPARFSFRLRPVFNASVQFLH 170
           V+P+  P P P  + L       +  + PPPP P P             P   A +Q   
Sbjct: 320 VSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAP 379

Query: 171 CQLSRCRRLRGVRRAPAPLTPP---PPPPPSRCLPQDEACADTGSGSAEGLAADGPHLHT 227
             L           AP P+ PP   P PP +R  P  E                   +H 
Sbjct: 380 GVL---------HPAPPPIAPPLVQPSPPVARAAPVCETVP----------------VHP 414

Query: 228 LTQPIVVTVPRPPPRPPKSVPGRAVRPEPP------APAPAALEPAPVVA 271
           L Q  V  +P PPP PP   PG  +RP  P      A  P+ L P P  A
Sbjct: 415 LPQGEVQGLPPPPPPPPLPPPG--IRPSSPVTVTALAHPPSGLHPTPSTA 462



 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 44/138 (31%), Positives = 55/138 (39%), Gaps = 19/138 (13%)

Query: 139 PPPPPPSPGA--ARPARFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAP---APLTPPP 193
           PPPPPP  GA  A+P        P   +S   L   +    +     R P   +P  PPP
Sbjct: 278 PPPPPPMHGAGDAKPI-------PTCISSATGL---IENRPQSPATGRTPVFVSPTPPPP 327

Query: 194 PPPPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPPPRPPKSVPGRAVR 253
           PPP    L      A   S     +    P   T  Q   V    PPP P +  PG  + 
Sbjct: 328 PPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVP---PPPAPLQIAPG-VLH 383

Query: 254 PEPPAPAPAALEPAPVVA 271
           P PP  AP  ++P+P VA
Sbjct: 384 PAPPPIAPPLVQPSPPVA 401



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 48/167 (28%), Positives = 60/167 (35%), Gaps = 34/167 (20%)

Query: 40  PPFPAPPAPPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPS 99
           PP P PP PP  A   P +  P   L+++      P    P   P      +   L +PS
Sbjct: 350 PPVPPPPPPPATALQAPAVPPPPAPLQIA------PGVLHPAPPP------IAPPLVQPS 397

Query: 100 PRWGLALHRCSVTPSSRPAPGPALALLREGCPADTSVAFPPPPPPSPGAARPARFSFRLR 159
           P    A   C   P   P P   +    +G P       PPPPPP P           +R
Sbjct: 398 PPVARAAPVCETVP-VHPLPQGEV----QGLPP------PPPPPPLPPPG--------IR 438

Query: 160 PVFNASVQFLHCQLSRCRRLRGVRRAPAPLTP-PPPPPPSRCLPQDE 205
           P    +V  L    S          AP P  P  PP PPS+ +P  E
Sbjct: 439 PSSPVTVTALAHPPSGLHPTPST--APGPHVPLMPPSPPSQVIPASE 483



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 38/113 (33%), Positives = 41/113 (36%), Gaps = 20/113 (17%)

Query: 188 PLTPPPPPPPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPPPRPP--- 244
           P  PPPPPP       D     T   SA GL  + P      +  V   P PPP PP   
Sbjct: 275 PHEPPPPPPMHGA--GDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLP 332

Query: 245 ------------KSVPGRAVRPEPPAPAPAALEPA---PVVALVLAAFVLGAA 282
                        S P   V P PP PA A   PA   P   L +A  VL  A
Sbjct: 333 SALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPA 385


>gi|66932986 filamin-binding LIM protein-1 isoform b [Homo sapiens]
          Length = 374

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 58/196 (29%), Positives = 70/196 (35%), Gaps = 66/196 (33%)

Query: 76  RRAGPLEVPADSRVFVQAALARPSPRWGLALHRCSVTPSSRPAPGPA--LALLREGCPAD 133
           RR  P E PA  +        RPSP W         TP    A  PA  + L   GCP  
Sbjct: 38  RRGRPWEAPAPMKTPEAGLAGRPSP-W--------TTPGRAAATVPAAPMQLFNGGCP-- 86

Query: 134 TSVAFPPPPPPSPGAARPARFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAPAPLTPPP 193
                 PPPP   G          + P  +                         L PPP
Sbjct: 87  ------PPPPVLDGED--------VLPDLD-------------------------LLPPP 107

Query: 194 PPPPSRCLP-QDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPPPRPPKSVPGRAV 252
           PPPP   LP ++EA A  G+     L AD   LH       ++ P PPP+ P    G +V
Sbjct: 108 PPPPPVLLPSEEEAPAPMGA----SLIADLEQLH-------LSPPPPPPQAP--AEGPSV 154

Query: 253 RPEPPAPAPAALEPAP 268
           +P P  P    L P P
Sbjct: 155 QPGPLRPMEEELPPPP 170


>gi|66932982 filamin-binding LIM protein-1 isoform a [Homo sapiens]
          Length = 373

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 58/196 (29%), Positives = 70/196 (35%), Gaps = 66/196 (33%)

Query: 76  RRAGPLEVPADSRVFVQAALARPSPRWGLALHRCSVTPSSRPAPGPA--LALLREGCPAD 133
           RR  P E PA  +        RPSP W         TP    A  PA  + L   GCP  
Sbjct: 38  RRGRPWEAPAPMKTPEAGLAGRPSP-W--------TTPGRAAATVPAAPMQLFNGGCP-- 86

Query: 134 TSVAFPPPPPPSPGAARPARFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAPAPLTPPP 193
                 PPPP   G          + P  +                         L PPP
Sbjct: 87  ------PPPPVLDGED--------VLPDLD-------------------------LLPPP 107

Query: 194 PPPPSRCLP-QDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPPPRPPKSVPGRAV 252
           PPPP   LP ++EA A  G+     L AD   LH       ++ P PPP+ P    G +V
Sbjct: 108 PPPPPVLLPSEEEAPAPMGA----SLIADLEQLH-------LSPPPPPPQAP--AEGPSV 154

Query: 253 RPEPPAPAPAALEPAP 268
           +P P  P    L P P
Sbjct: 155 QPGPLRPMEEELPPPP 170


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 69/233 (29%), Positives = 84/233 (36%), Gaps = 22/233 (9%)

Query: 41  PFPAPPAPPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPSP 100
           P P P  PPFP   G  L     S++ S      P    P   P  SR         P P
Sbjct: 213 PSPGPTPPPFPGNRGTALGGG--SIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPP 270

Query: 101 RWGL-ALHRCSVTPSSRPAPGPALALLREGCPADTSVAFPPPPPPSPGAARPARFSF--- 156
                ++HR +V P       P +       P+ +S A PPPPPPS     P   S    
Sbjct: 271 VGNRPSIHREAVPPPPPQNNKPPVPSTPR--PSASSQAPPPPPPPSRPGPPPLPPSSSGN 328

Query: 157 ----RLRPVFNASVQFLHCQLSRCRRLRGVRRAPAPLTPPPPP---PPSRCLPQDEACAD 209
               RL P  N S+      L    R   +   P P   PPPP   PP R  P       
Sbjct: 329 DETPRL-PQRNLSLSSSTPPLPSPGRSGPL--PPPPSERPPPPVRDPPGRSGPLPPPPPV 385

Query: 210 TGSGSAEGLAADGPHLHTLTQPIVVTVPRPPPRPPKSVPGRAVRPEPPAPAPA 262
           + +GS        P L + +    V  PR  PRPP   P R     PP P P+
Sbjct: 386 SRNGSTSRALPATPQLPSRSG---VDSPRSGPRPPLP-PDRPSAGAPPPPPPS 434



 Score = 48.1 bits (113), Expect = 9e-06
 Identities = 73/269 (27%), Positives = 94/269 (34%), Gaps = 50/269 (18%)

Query: 26  PGGLKGSARFLSFGPP-----FPAPPAPPFPAAPGPWLRR-PLFSLKLSDTEDVFPRRAG 79
           PGG   SA+   F PP     FP P        P P   R P     +    D  P    
Sbjct: 131 PGGRSTSAK--PFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPP--- 185

Query: 80  PLEVPADSRVFVQAALARPSPRWGLALHRCSVTPSSRPAPGPALALLREGC----PADTS 135
              VP+  R    +   R SP       + S  P+  P PG     L  G     P  +S
Sbjct: 186 --PVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSS 243

Query: 136 VAFP----------------PPPPPSPGAARPARFSFRLRPVFNASVQFLHCQLSRCRRL 179
             F                 PPPPP P   RP+        +   +V     Q ++    
Sbjct: 244 SPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPS--------IHREAVPPPPPQNNKPPVP 295

Query: 180 RGVRRAPAPLTPPPPPPPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVV---TV 236
              R + +   PPPPPPPSR  P     + +G+     L      L + T P+     + 
Sbjct: 296 STPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSG 355

Query: 237 PRPPP---RPPKSV---PGRAVRPEPPAP 259
           P PPP   RPP  V   PGR+    PP P
Sbjct: 356 PLPPPPSERPPPPVRDPPGRSGPLPPPPP 384



 Score = 37.4 bits (85), Expect = 0.017
 Identities = 56/194 (28%), Positives = 71/194 (36%), Gaps = 34/194 (17%)

Query: 44  APPAPPFPAAPGP------------WLRRPLFSLKLSDTEDVFPR--RAGPLEVPADSRV 89
           APP PP P+ PGP              R P  +L LS +    P   R+GPL  P   R 
Sbjct: 306 APPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERP 365

Query: 90  FVQAALARPSPRWGLALHRCSVT---PSSRPAPGPALALLREGCPADTSVAFPPPPPPSP 146
                +  P  R G       V+    +SR  P       R G  +  S   PP PP  P
Sbjct: 366 --PPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRP 423

Query: 147 --GAARPARFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAPAPLTPPPPPPP----SRC 200
             GA  P   S  +R  F         Q S C      R    P++  PPP P    ++ 
Sbjct: 424 SAGAPPPPPPSTSIRNGF---------QDSPCEDEWESRFYFHPISDLPPPEPYVQTTKS 474

Query: 201 LPQDEACADTGSGS 214
            P   A  ++ SGS
Sbjct: 475 YPSKLARNESRSGS 488


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 69/233 (29%), Positives = 84/233 (36%), Gaps = 22/233 (9%)

Query: 41  PFPAPPAPPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPSP 100
           P P P  PPFP   G  L     S++ S      P    P   P  SR         P P
Sbjct: 213 PSPGPTPPPFPGNRGTALGGG--SIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPP 270

Query: 101 RWGL-ALHRCSVTPSSRPAPGPALALLREGCPADTSVAFPPPPPPSPGAARPARFSF--- 156
                ++HR +V P       P +       P+ +S A PPPPPPS     P   S    
Sbjct: 271 VGNRPSIHREAVPPPPPQNNKPPVPSTPR--PSASSQAPPPPPPPSRPGPPPLPPSSSGN 328

Query: 157 ----RLRPVFNASVQFLHCQLSRCRRLRGVRRAPAPLTPPPPP---PPSRCLPQDEACAD 209
               RL P  N S+      L    R   +   P P   PPPP   PP R  P       
Sbjct: 329 DETPRL-PQRNLSLSSSTPPLPSPGRSGPL--PPPPSERPPPPVRDPPGRSGPLPPPPPV 385

Query: 210 TGSGSAEGLAADGPHLHTLTQPIVVTVPRPPPRPPKSVPGRAVRPEPPAPAPA 262
           + +GS        P L + +    V  PR  PRPP   P R     PP P P+
Sbjct: 386 SRNGSTSRALPATPQLPSRSG---VDSPRSGPRPPLP-PDRPSAGAPPPPPPS 434



 Score = 48.1 bits (113), Expect = 9e-06
 Identities = 73/269 (27%), Positives = 94/269 (34%), Gaps = 50/269 (18%)

Query: 26  PGGLKGSARFLSFGPP-----FPAPPAPPFPAAPGPWLRR-PLFSLKLSDTEDVFPRRAG 79
           PGG   SA+   F PP     FP P        P P   R P     +    D  P    
Sbjct: 131 PGGRSTSAK--PFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPP--- 185

Query: 80  PLEVPADSRVFVQAALARPSPRWGLALHRCSVTPSSRPAPGPALALLREGC----PADTS 135
              VP+  R    +   R SP       + S  P+  P PG     L  G     P  +S
Sbjct: 186 --PVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSS 243

Query: 136 VAFP----------------PPPPPSPGAARPARFSFRLRPVFNASVQFLHCQLSRCRRL 179
             F                 PPPPP P   RP+        +   +V     Q ++    
Sbjct: 244 SPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPS--------IHREAVPPPPPQNNKPPVP 295

Query: 180 RGVRRAPAPLTPPPPPPPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVV---TV 236
              R + +   PPPPPPPSR  P     + +G+     L      L + T P+     + 
Sbjct: 296 STPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSG 355

Query: 237 PRPPP---RPPKSV---PGRAVRPEPPAP 259
           P PPP   RPP  V   PGR+    PP P
Sbjct: 356 PLPPPPSERPPPPVRDPPGRSGPLPPPPP 384



 Score = 37.4 bits (85), Expect = 0.017
 Identities = 56/194 (28%), Positives = 71/194 (36%), Gaps = 34/194 (17%)

Query: 44  APPAPPFPAAPGP------------WLRRPLFSLKLSDTEDVFPR--RAGPLEVPADSRV 89
           APP PP P+ PGP              R P  +L LS +    P   R+GPL  P   R 
Sbjct: 306 APPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERP 365

Query: 90  FVQAALARPSPRWGLALHRCSVT---PSSRPAPGPALALLREGCPADTSVAFPPPPPPSP 146
                +  P  R G       V+    +SR  P       R G  +  S   PP PP  P
Sbjct: 366 --PPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRP 423

Query: 147 --GAARPARFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAPAPLTPPPPPPP----SRC 200
             GA  P   S  +R  F         Q S C      R    P++  PPP P    ++ 
Sbjct: 424 SAGAPPPPPPSTSIRNGF---------QDSPCEDEWESRFYFHPISDLPPPEPYVQTTKS 474

Query: 201 LPQDEACADTGSGS 214
            P   A  ++ SGS
Sbjct: 475 YPSKLARNESRSGS 488


>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
           sapiens]
          Length = 483

 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 68/240 (28%), Positives = 81/240 (33%), Gaps = 53/240 (22%)

Query: 31  GSARFLSFGPPFPAPPAPPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVF 90
           G+AR     P  PAPP PP P  P P L  PL S     T  V P   GPL       V 
Sbjct: 160 GAARTAPPRPNVPAPP-PPTPPPPPPPLPPPLPSSSPIKTPLVSP--PGPLTKGNLPVVA 216

Query: 91  VQAALARPSPRWGLALHRCSVTPSSRPAPGPALALLREGC--PADTSVAFPPPPPPSPGA 148
                A P P            P   P P P  ++L +    P    +  PP PPP P  
Sbjct: 217 PPVPCAPPPP---------PPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLL 267

Query: 149 ARPARFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAPAPLTPPPPPPPSRCLPQDEACA 208
                   +  P   A               +  +  PAP  PPP PP + C P+    A
Sbjct: 268 PPCGYPGLKAEPASPA---------------QDAQEPPAP--PPPLPPYASCSPRASLPA 310

Query: 209 DTGSGSAEGLAADGPHLHTLTQPIVVTVPRPPPRPPKSVPGRAVRPEPPAPAPAALEPAP 268
               G                  +  +   PPP PPKS   +A    PP  A A   PAP
Sbjct: 311 PPLPG------------------VNSSSETPPPLPPKSPSFQA----PPQKAGAQALPAP 348



 Score = 32.0 bits (71), Expect = 0.70
 Identities = 32/116 (27%), Positives = 41/116 (35%), Gaps = 33/116 (28%)

Query: 40  PPFPAPPAPPF---------PAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVF 90
           PP P PP PP+         PA P P +         S+T    P ++   + P   +  
Sbjct: 289 PPAPPPPLPPYASCSPRASLPAPPLPGVNSS------SETPPPLPPKSPSFQAPPQ-KAG 341

Query: 91  VQAALARPSPRWGLALHRCSVTPSSRPAPGPALALLREGCP-ADTSVAFPPPPPPS 145
            QA  A P+P                P   P L   R G P A      PPP PP+
Sbjct: 342 AQALPAPPAP----------------PGSQPFLQKKRHGRPGAGGGKLNPPPAPPA 381



 Score = 30.0 bits (66), Expect = 2.7
 Identities = 29/96 (30%), Positives = 34/96 (35%), Gaps = 16/96 (16%)

Query: 184 RAPAPLTP------PPPPPPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVP 237
           RAP+P  P      P  PP S  L          +  A G A   P    +  P   T P
Sbjct: 129 RAPSPRLPNKTISGPLIPPASPRLGN--------TSEAHGAARTAPPRPNVPAPPPPTPP 180

Query: 238 RPPPRPPKSVPGRAVRPEP--PAPAPAALEPAPVVA 271
            PPP  P  +P  +    P    P P      PVVA
Sbjct: 181 PPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVA 216



 Score = 29.3 bits (64), Expect = 4.6
 Identities = 13/32 (40%), Positives = 16/32 (50%)

Query: 234 VTVPRPPPRPPKSVPGRAVRPEPPAPAPAALE 265
           V  P PPP PP   P  A  P PP+  P + +
Sbjct: 3   VPPPPPPPLPPPPPPLGAPPPPPPSAPPVSTD 34


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.139    0.449 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,913,110
Number of Sequences: 37866
Number of extensions: 1521594
Number of successful extensions: 35863
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 471
Number of HSP's successfully gapped in prelim test: 1249
Number of HSP's that attempted gapping in prelim test: 14793
Number of HSP's gapped (non-prelim): 13218
length of query: 306
length of database: 18,247,518
effective HSP length: 102
effective length of query: 204
effective length of database: 14,385,186
effective search space: 2934577944
effective search space used: 2934577944
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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