Guide to the Human Genome
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Search of human proteins with 11995472

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|11995472 Ras-related GTP binding C [Homo sapiens]
         (399 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|11995472 Ras-related GTP binding C [Homo sapiens]                  802   0.0  
gi|11034847 Ras-related GTP binding D [Homo sapiens]                  600   e-172
gi|46249395 Ras-related GTP binding B short isoform [Homo sapiens]     80   3e-15
gi|5729999 Ras-related GTP binding A [Homo sapiens]                    79   7e-15
gi|46249397 Ras-related GTP binding B long isoform [Homo sapiens]      72   7e-13
gi|106507164 RAB12, member RAS oncogene family [Homo sapiens]          37   0.031
gi|4757774 ADP-ribosylation factor-like 3 [Homo sapiens]               36   0.054
gi|41393614 RAB5C, member RAS oncogene family isoform a [Homo sa...    35   0.092
gi|41393545 RAB5C, member RAS oncogene family isoform b [Homo sa...    35   0.092
gi|4502211 ADP-ribosylation factor 6 [Homo sapiens]                    35   0.12 
gi|73427806 v-maf musculoaponeurotic fibrosarcoma oncogene homol...    35   0.12 
gi|5453736 v-maf musculoaponeurotic fibrosarcoma oncogene homolo...    35   0.12 
gi|19923979 ADP-ribosylation factor-like 11 [Homo sapiens]             35   0.16 
gi|28376635 RAB37, member RAS oncogene family isoform 3 [Homo sa...    35   0.16 
gi|7710121 engrailed homeobox 2 [Homo sapiens]                         35   0.16 
gi|13994190 frizzled 8 [Homo sapiens]                                  35   0.16 
gi|8922601 ADP-ribosylation factor-like 10C [Homo sapiens]             35   0.16 
gi|229577180 MPN domain containing isoform 2 [Homo sapiens]            34   0.20 
gi|31542699 MPN domain containing isoform 1 [Homo sapiens]             34   0.20 
gi|19923262 RAB5A, member RAS oncogene family [Homo sapiens]           34   0.20 
gi|66879664 ADP-ribosylation factor 1 [Homo sapiens]                   34   0.20 
gi|66879662 ADP-ribosylation factor 1 [Homo sapiens]                   34   0.20 
gi|66879660 ADP-ribosylation factor 1 [Homo sapiens]                   34   0.20 
gi|4502201 ADP-ribosylation factor 1 [Homo sapiens]                    34   0.20 
gi|4502203 ADP-ribosylation factor 3 [Homo sapiens]                    34   0.20 
gi|5174607 NGFI-A binding protein 2 [Homo sapiens]                     34   0.20 
gi|38787935 BMP-2 inducible kinase isoform a [Homo sapiens]            34   0.27 
gi|38787904 BMP-2 inducible kinase isoform b [Homo sapiens]            34   0.27 
gi|51702521 POU domain, class 3, transcription factor 2 [Homo sa...    34   0.27 
gi|34486092 adenylate cyclase 5 [Homo sapiens]                         34   0.27 

>gi|11995472 Ras-related GTP binding C [Homo sapiens]
          Length = 399

 Score =  802 bits (2072), Expect = 0.0
 Identities = 399/399 (100%), Positives = 399/399 (100%)

Query: 1   MSLQYGAEETPLAGSYGAADSFPKDFGYGVEEEEEEAAAAGGGVGAGAGGGCGPGGADSS 60
           MSLQYGAEETPLAGSYGAADSFPKDFGYGVEEEEEEAAAAGGGVGAGAGGGCGPGGADSS
Sbjct: 1   MSLQYGAEETPLAGSYGAADSFPKDFGYGVEEEEEEAAAAGGGVGAGAGGGCGPGGADSS 60

Query: 61  KPRILLMGLRRSGKSSIQKVVFHKMSPNETLFLESTNKIYKDDISNSSFVNFQIWDFPGQ 120
           KPRILLMGLRRSGKSSIQKVVFHKMSPNETLFLESTNKIYKDDISNSSFVNFQIWDFPGQ
Sbjct: 61  KPRILLMGLRRSGKSSIQKVVFHKMSPNETLFLESTNKIYKDDISNSSFVNFQIWDFPGQ 120

Query: 121 MDFFDPTFDYEMIFRGTGALIYVIDAQDDYMEALTRLHITVSKAYKVNPDMNFEVFIHKV 180
           MDFFDPTFDYEMIFRGTGALIYVIDAQDDYMEALTRLHITVSKAYKVNPDMNFEVFIHKV
Sbjct: 121 MDFFDPTFDYEMIFRGTGALIYVIDAQDDYMEALTRLHITVSKAYKVNPDMNFEVFIHKV 180

Query: 181 DGLSDDHKIETQRDIHQRANDDLADAGLEKLHLSFYLTSIYDHSIFEAFSKVVQKLIPQL 240
           DGLSDDHKIETQRDIHQRANDDLADAGLEKLHLSFYLTSIYDHSIFEAFSKVVQKLIPQL
Sbjct: 181 DGLSDDHKIETQRDIHQRANDDLADAGLEKLHLSFYLTSIYDHSIFEAFSKVVQKLIPQL 240

Query: 241 PTLENLLNIFISNSGIEKAFLFDVVSKIYIATDSSPVDMQSYELCCDMIDVVIDVSCIYG 300
           PTLENLLNIFISNSGIEKAFLFDVVSKIYIATDSSPVDMQSYELCCDMIDVVIDVSCIYG
Sbjct: 241 PTLENLLNIFISNSGIEKAFLFDVVSKIYIATDSSPVDMQSYELCCDMIDVVIDVSCIYG 300

Query: 301 LKEDGSGSAYDKESMAIIKLNNTTVLYLKEVTKFLALVCILREESFERKGLIDYNFHCFR 360
           LKEDGSGSAYDKESMAIIKLNNTTVLYLKEVTKFLALVCILREESFERKGLIDYNFHCFR
Sbjct: 301 LKEDGSGSAYDKESMAIIKLNNTTVLYLKEVTKFLALVCILREESFERKGLIDYNFHCFR 360

Query: 361 KAIHEVFEVGVTSHRSCGHQTSASSLKALTHNGTPRNAI 399
           KAIHEVFEVGVTSHRSCGHQTSASSLKALTHNGTPRNAI
Sbjct: 361 KAIHEVFEVGVTSHRSCGHQTSASSLKALTHNGTPRNAI 399


>gi|11034847 Ras-related GTP binding D [Homo sapiens]
          Length = 400

 Score =  600 bits (1546), Expect = e-172
 Identities = 308/388 (79%), Positives = 329/388 (84%), Gaps = 14/388 (3%)

Query: 23  PKDFGYGVEEEEEEAAAAGGGVGAGAGG-------GCGPGGADSS-------KPRILLMG 68
           P+D     EEEEE+        G G          G   G  D S       KPRILLMG
Sbjct: 10  PQDEDDAEEEEEEDELVGLADYGDGPDSSDADPDSGTEEGVLDFSDPFSTEVKPRILLMG 69

Query: 69  LRRSGKSSIQKVVFHKMSPNETLFLESTNKIYKDDISNSSFVNFQIWDFPGQMDFFDPTF 128
           LRRSGKSSIQKVVFHKMSPNETLFLESTNKI ++D+SNSSFVNFQIWDFPGQ+DFFDPTF
Sbjct: 70  LRRSGKSSIQKVVFHKMSPNETLFLESTNKICREDVSNSSFVNFQIWDFPGQIDFFDPTF 129

Query: 129 DYEMIFRGTGALIYVIDAQDDYMEALTRLHITVSKAYKVNPDMNFEVFIHKVDGLSDDHK 188
           DYEMIFRGTGALI+VID+QDDYMEAL RLH+TV++AYKVN D+NFEVFIHKVDGLSDDHK
Sbjct: 130 DYEMIFRGTGALIFVIDSQDDYMEALARLHLTVTRAYKVNTDINFEVFIHKVDGLSDDHK 189

Query: 189 IETQRDIHQRANDDLADAGLEKLHLSFYLTSIYDHSIFEAFSKVVQKLIPQLPTLENLLN 248
           IETQRDIHQRANDDLADAGLEK+HLSFYLTSIYDHSIFEAFSKVVQKLIPQLPTLENLLN
Sbjct: 190 IETQRDIHQRANDDLADAGLEKIHLSFYLTSIYDHSIFEAFSKVVQKLIPQLPTLENLLN 249

Query: 249 IFISNSGIEKAFLFDVVSKIYIATDSSPVDMQSYELCCDMIDVVIDVSCIYGLKEDGSGS 308
           IFISNSGIEKAFLFDVVSKIYIATDS+PVDMQ+YELCCDMIDVVID+SCIYGLKEDG+G+
Sbjct: 250 IFISNSGIEKAFLFDVVSKIYIATDSTPVDMQTYELCCDMIDVVIDISCIYGLKEDGAGT 309

Query: 309 AYDKESMAIIKLNNTTVLYLKEVTKFLALVCILREESFERKGLIDYNFHCFRKAIHEVFE 368
            YDKES AIIKLNNTTVLYLKEVTKFLALVC +REESFERKGLIDYNFHCFRKAIHEVFE
Sbjct: 310 PYDKESTAIIKLNNTTVLYLKEVTKFLALVCFVREESFERKGLIDYNFHCFRKAIHEVFE 369

Query: 369 VGVTSHRSCGHQTSASSLKALTHNGTPR 396
           V +   +S   Q      K  T NGTPR
Sbjct: 370 VRMKVVKSRKVQNRLQKKKRATPNGTPR 397


>gi|46249395 Ras-related GTP binding B short isoform [Homo sapiens]
          Length = 346

 Score = 80.1 bits (196), Expect = 3e-15
 Identities = 58/214 (27%), Positives = 102/214 (47%), Gaps = 8/214 (3%)

Query: 61  KPRILLMGLRRSGKSSIQKVVFHKMSPNETLFLESTNKIYKDDISNSSFVNFQIWDFPGQ 120
           K ++LLMG   SGK+S++ ++F      +T  L +T  +    +     +   +WD  GQ
Sbjct: 40  KKKVLLMGKSGSGKTSMRSIIFANYIARDTRRLGATIDVEHSHVRFLGNLVLNLWDCGGQ 99

Query: 121 MDFFDPTFDYEM--IFRGTGALIYVIDAQDDYMEALTRLHITVSKAYKVN-PDMNFEVFI 177
             F +  F  +   IFR    LIYV D +   +E     + +  +A   N PD      +
Sbjct: 100 DTFMENYFTSQRDNIFRNVEVLIYVFDVESRELEKDMHYYQSCLEAILQNSPDAKIFCLV 159

Query: 178 HKVDGLSDDHKIETQRDIHQRANDDLADAGLEKLHLSFYLTSIYDHSIFEAFSKVVQKLI 237
           HK+D + +D     QRD+  +  ++        L  S + TSI+D ++++A+S +V +LI
Sbjct: 160 HKMDLVQED-----QRDLIFKEREEDLRRLSRPLECSCFRTSIWDETLYKAWSSIVYQLI 214

Query: 238 PQLPTLENLLNIFISNSGIEKAFLFDVVSKIYIA 271
           P +  LE  L  F      ++  LF+  + + I+
Sbjct: 215 PNVQQLEMNLRNFAEIIEADEVLLFERATFLVIS 248


>gi|5729999 Ras-related GTP binding A [Homo sapiens]
          Length = 313

 Score = 79.0 bits (193), Expect = 7e-15
 Identities = 57/214 (26%), Positives = 102/214 (47%), Gaps = 8/214 (3%)

Query: 61  KPRILLMGLRRSGKSSIQKVVFHKMSPNETLFLESTNKIYKDDISNSSFVNFQIWDFPGQ 120
           K ++LLMG   SGK+S++ ++F      +T  L +T  +    +     +   +WD  GQ
Sbjct: 7   KKKVLLMGKSGSGKTSMRSIIFANYIARDTRRLGATIDVEHSHVRFLGNLVLNLWDCGGQ 66

Query: 121 MDFFDPTF--DYEMIFRGTGALIYVIDAQDDYMEALTRLHITVSKAYKVN-PDMNFEVFI 177
             F +  F    + IFR    LIYV D +   +E     + +  +A   N PD      +
Sbjct: 67  DTFMENYFTSQRDNIFRNVEVLIYVFDVESRELEKDMHYYQSCLEAILQNSPDAKIFCLV 126

Query: 178 HKVDGLSDDHKIETQRDIHQRANDDLADAGLEKLHLSFYLTSIYDHSIFEAFSKVVQKLI 237
           HK+D + +D     QRD+  +  ++        L  + + TSI+D ++++A+S +V +LI
Sbjct: 127 HKMDLVQED-----QRDLIFKEREEDLRRLSRPLECACFRTSIWDETLYKAWSSIVYQLI 181

Query: 238 PQLPTLENLLNIFISNSGIEKAFLFDVVSKIYIA 271
           P +  LE  L  F      ++  LF+  + + I+
Sbjct: 182 PNVQQLEMNLRNFAQIIEADEVLLFERATFLVIS 215


>gi|46249397 Ras-related GTP binding B long isoform [Homo sapiens]
          Length = 374

 Score = 72.4 bits (176), Expect = 7e-13
 Identities = 64/242 (26%), Positives = 110/242 (45%), Gaps = 36/242 (14%)

Query: 61  KPRILLMGLRRSGKSSIQKVVFHKMSPNETLFLEST--NKIYKDDISNS----------- 107
           K ++LLMG   SGK+S++ ++F      +T  L +T  ++I+   I++S           
Sbjct: 40  KKKVLLMGKSGSGKTSMRSIIFANYIARDTRRLGATILDRIHSLQINSSLSTYSLVDSVG 99

Query: 108 ---------SFVNF------QIWDFPGQMDFFDPTFDYEM--IFRGTGALIYVIDAQDDY 150
                    S V F       +WD  GQ  F +  F  +   IFR    LIYV D +   
Sbjct: 100 NTKTFDVEHSHVRFLGNLVLNLWDCGGQDTFMENYFTSQRDNIFRNVEVLIYVFDVESRE 159

Query: 151 MEALTRLHITVSKAYKVN-PDMNFEVFIHKVDGLSDDHKIETQRDIHQRANDDLADAGLE 209
           +E     + +  +A   N PD      +HK+D + +D     QRD+  +  ++       
Sbjct: 160 LEKDMHYYQSCLEAILQNSPDAKIFCLVHKMDLVQED-----QRDLIFKEREEDLRRLSR 214

Query: 210 KLHLSFYLTSIYDHSIFEAFSKVVQKLIPQLPTLENLLNIFISNSGIEKAFLFDVVSKIY 269
            L  S + TSI+D ++++A+S +V +LIP +  LE  L  F      ++  LF+  + + 
Sbjct: 215 PLECSCFRTSIWDETLYKAWSSIVYQLIPNVQQLEMNLRNFAEIIEADEVLLFERATFLV 274

Query: 270 IA 271
           I+
Sbjct: 275 IS 276


>gi|106507164 RAB12, member RAS oncogene family [Homo sapiens]
          Length = 244

 Score = 37.0 bits (84), Expect = 0.031
 Identities = 53/236 (22%), Positives = 96/236 (40%), Gaps = 39/236 (16%)

Query: 35  EEAAAAGGGVGAGAGGGCGPGGADSSKP--------RILLMGLRRSGKSSIQKVVFHKMS 86
           +  A  GGG+GAG+    G  G    +P        +++++G R  GK+S+ +       
Sbjct: 8   QRRAGGGGGLGAGSPALSGGQGRRRKQPPRPADFKLQVIIIGSRGVGKTSLMERF----- 62

Query: 87  PNETLFLESTNKIYKDDIS------NSSFVNFQIWDFPGQMDFFDPTFDYEMIFRGTGAL 140
             +  F E+       D            +  QIWD  GQ  F   T  Y   +R    +
Sbjct: 63  -TDDTFCEACKSTVGVDFKIKTVELRGKKIRLQIWDTAGQERFNSITSAY---YRSAKGI 118

Query: 141 IYVID-AQDDYMEALTRLHITVSKAYKVNPDMNFEVFIHKVDGLSDDHKIETQRDIHQRA 199
           I V D  + +  + L +    + K    + D    +  +K+D        ET R+I ++ 
Sbjct: 119 ILVYDITKKETFDDLPKWMKMIDK--YASEDAELLLVGNKLD-------CETDREITRQQ 169

Query: 200 NDDLADAGLEKLHLSFYLTSIYDH-SIFEAFSKVVQKLIPQLPTLENLLNIFISNS 254
            +  A    +   + F   S  D+ ++ E F K+V  ++ ++P   ++L   +SNS
Sbjct: 170 GEKFAQ---QITGMRFCEASAKDNFNVDEIFLKLVDDILKKMPL--DILRNELSNS 220


>gi|4757774 ADP-ribosylation factor-like 3 [Homo sapiens]
          Length = 182

 Score = 36.2 bits (82), Expect = 0.054
 Identities = 26/92 (28%), Positives = 42/92 (45%), Gaps = 8/92 (8%)

Query: 57  ADSSKPRILLMGLRRSGKSSIQKVVFHKMSPNETLFLESTNKIYKDDISNSSFVNFQIWD 116
           A   + RILL+GL  +GK+++ K    +++  +   +  T       + +  F    +WD
Sbjct: 13  APDQEVRILLLGLDNAGKTTLLK----QLASEDISHITPTQGFNIKSVQSQGF-KLNVWD 67

Query: 117 FPGQMDFFDPTFDYEMIFRGTGALIYVIDAQD 148
             GQ        +Y   F  T  LIYVID+ D
Sbjct: 68  IGGQRKIRPYWKNY---FENTDILIYVIDSAD 96


>gi|41393614 RAB5C, member RAS oncogene family isoform a [Homo
           sapiens]
          Length = 216

 Score = 35.4 bits (80), Expect = 0.092
 Identities = 32/108 (29%), Positives = 45/108 (41%), Gaps = 15/108 (13%)

Query: 46  AGAGGGCGPGGADSSKP----RILLMGLRRSGKSSIQ----KVVFHKMSPNETLFLESTN 97
           AG GG   P G  +       +++L+G    GKSS+     K  FH+   +       T 
Sbjct: 2   AGRGGAARPNGPAAGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQ 61

Query: 98  KIYKDDISNSSFVNFQIWDFPGQMDFFDPTFDYEMIFRGTGALIYVID 145
            +  DD +    V F+IWD  GQ  +        M +RG  A I V D
Sbjct: 62  TVCLDDTT----VKFEIWDTAGQERYHSLA---PMYYRGAQAAIVVYD 102


>gi|41393545 RAB5C, member RAS oncogene family isoform b [Homo
           sapiens]
          Length = 216

 Score = 35.4 bits (80), Expect = 0.092
 Identities = 32/108 (29%), Positives = 45/108 (41%), Gaps = 15/108 (13%)

Query: 46  AGAGGGCGPGGADSSKP----RILLMGLRRSGKSSIQ----KVVFHKMSPNETLFLESTN 97
           AG GG   P G  +       +++L+G    GKSS+     K  FH+   +       T 
Sbjct: 2   AGRGGAARPNGPAAGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQ 61

Query: 98  KIYKDDISNSSFVNFQIWDFPGQMDFFDPTFDYEMIFRGTGALIYVID 145
            +  DD +    V F+IWD  GQ  +        M +RG  A I V D
Sbjct: 62  TVCLDDTT----VKFEIWDTAGQERYHSLA---PMYYRGAQAAIVVYD 102


>gi|4502211 ADP-ribosylation factor 6 [Homo sapiens]
          Length = 175

 Score = 35.0 bits (79), Expect = 0.12
 Identities = 29/98 (29%), Positives = 50/98 (51%), Gaps = 10/98 (10%)

Query: 63  RILLMGLRRSGKSSIQKVVFHKMSPNETLFLESTNKIYKDDISNSSFVNFQIWDFPGQMD 122
           RIL++GL  +GK++I     +K+   +++    T     + ++  + V F +WD  GQ D
Sbjct: 15  RILMLGLDAAGKTTI----LYKLKLGQSVTTIPTVGFNVETVTYKN-VKFNVWDVGGQ-D 68

Query: 123 FFDPTFDYEMIFRGTGALIYVIDA--QDDYMEALTRLH 158
              P + +   + GT  LI+V+D   +D   EA   LH
Sbjct: 69  KIRPLWRH--YYTGTQGLIFVVDCADRDRIDEARQELH 104


>gi|73427806 v-maf musculoaponeurotic fibrosarcoma oncogene homolog
           isoform b [Homo sapiens]
          Length = 373

 Score = 35.0 bits (79), Expect = 0.12
 Identities = 28/78 (35%), Positives = 35/78 (44%), Gaps = 2/78 (2%)

Query: 6   GAEETPLAGSYGAADSFPKDFG-YGVEEEEEEAAAAGGGVGAGAGGGCGPGGADSS-KPR 63
           G    P AG+ GAA S     G  G       A+A GGG G G GGG G  GA  +  P 
Sbjct: 190 GHHHHPTAGAPGAAGSAAASAGGAGGAGGGGPASAGGGGGGGGGGGGGGAAGAGGALHPH 249

Query: 64  ILLMGLRRSGKSSIQKVV 81
               GL    + S +++V
Sbjct: 250 HAAGGLHFDDRFSDEQLV 267


>gi|5453736 v-maf musculoaponeurotic fibrosarcoma oncogene homolog
           isoform a [Homo sapiens]
          Length = 403

 Score = 35.0 bits (79), Expect = 0.12
 Identities = 28/78 (35%), Positives = 35/78 (44%), Gaps = 2/78 (2%)

Query: 6   GAEETPLAGSYGAADSFPKDFG-YGVEEEEEEAAAAGGGVGAGAGGGCGPGGADSS-KPR 63
           G    P AG+ GAA S     G  G       A+A GGG G G GGG G  GA  +  P 
Sbjct: 190 GHHHHPTAGAPGAAGSAAASAGGAGGAGGGGPASAGGGGGGGGGGGGGGAAGAGGALHPH 249

Query: 64  ILLMGLRRSGKSSIQKVV 81
               GL    + S +++V
Sbjct: 250 HAAGGLHFDDRFSDEQLV 267


>gi|19923979 ADP-ribosylation factor-like 11 [Homo sapiens]
          Length = 196

 Score = 34.7 bits (78), Expect = 0.16
 Identities = 21/90 (23%), Positives = 44/90 (48%), Gaps = 7/90 (7%)

Query: 60  SKPRILLMGLRRSGKSSIQKVVFHKMSPNETLFLESTNKIYKDDISNSSFVNFQIWDFPG 119
           ++ ++++MGL  +GK+++     +K+  ++ +    T     + +     V+  +WD  G
Sbjct: 11  AEAQVVMMGLDSAGKTTL----LYKLKGHQLVETLPTVGFNVEPLKAPGHVSLTLWDVGG 66

Query: 120 QMDFFDPTFDYEMIFRGTGALIYVIDAQDD 149
           Q        DY     GT  L+YV+D+ D+
Sbjct: 67  QAPLRASWKDY---LEGTDILVYVLDSTDE 93


>gi|28376635 RAB37, member RAS oncogene family isoform 3 [Homo
           sapiens]
          Length = 216

 Score = 34.7 bits (78), Expect = 0.16
 Identities = 41/147 (27%), Positives = 60/147 (40%), Gaps = 20/147 (13%)

Query: 50  GGCGPGGADSSKPRILLMGLRRSGKSSI----QKVVFHKMSPNETLFLESTNKIYKDDIS 105
           GG GP   D    + +L+G    GK+S+     +  F   S + T+ +  TNK+   D  
Sbjct: 11  GGAGPDFNDHVLHKTILVGDSGVGKTSLLVQFDQGKFIPGSFSATVGIGFTNKVVTVD-- 68

Query: 106 NSSFVNFQIWDFPGQMDFFDPTFDYEMIFRGTGALIYVID-----AQDDYMEALTRLHIT 160
               V  QIWD  GQ  F   T  Y   +R   AL+ + D     + D+    LT +H  
Sbjct: 69  -GVRVKLQIWDTAGQERFRSVTHAY---YRDAQALLLLYDITNKSSFDNIRAWLTEIHEY 124

Query: 161 VSKAYKV-----NPDMNFEVFIHKVDG 182
             +   +       DM+ E  I   DG
Sbjct: 125 AQRDVVIMLLGNKADMSSERVIRSEDG 151


>gi|7710121 engrailed homeobox 2 [Homo sapiens]
          Length = 333

 Score = 34.7 bits (78), Expect = 0.16
 Identities = 17/48 (35%), Positives = 27/48 (56%), Gaps = 2/48 (4%)

Query: 20 DSFPKDFGYGVEEEEEEAAAAGGGVGAGAGGGCGPGGADSSKPRILLM 67
          D  P +    VE + +  ++ GGG  +G GGG  PG AD+ + R L++
Sbjct: 5  DPKPGEAAAAVEGQRQPESSPGGG--SGGGGGSSPGEADTGRRRALML 50



 Score = 28.9 bits (63), Expect = 8.6
 Identities = 13/21 (61%), Positives = 14/21 (66%)

Query: 38  AAAGGGVGAGAGGGCGPGGAD 58
           A AGGG G GAGG  G  GA+
Sbjct: 90  AGAGGGRGGGAGGEGGASGAE 110


>gi|13994190 frizzled 8 [Homo sapiens]
          Length = 694

 Score = 34.7 bits (78), Expect = 0.16
 Identities = 15/20 (75%), Positives = 15/20 (75%)

Query: 37  AAAAGGGVGAGAGGGCGPGG 56
           A AAGGG G G GGG GPGG
Sbjct: 635 ATAAGGGGGPGGGGGGGPGG 654



 Score = 33.5 bits (75), Expect = 0.35
 Identities = 22/48 (45%), Positives = 25/48 (52%), Gaps = 3/48 (6%)

Query: 41  GGGVGAGAGGGCGPGGADSSKPRILLMGLR-RSGKSSIQKVVFHKMSP 87
           GGG G G GGG GPGG   S    +  GL  RSG +S   V + K  P
Sbjct: 645 GGGGGGGPGGGGGPGGGGGSLYSDVSTGLTWRSGTAS--SVSYPKQMP 690



 Score = 32.7 bits (73), Expect = 0.59
 Identities = 16/28 (57%), Positives = 17/28 (60%), Gaps = 1/28 (3%)

Query: 36  EAAAAGGGVGA-GAGGGCGPGGADSSKP 62
           + AA GGG GA  AGGG GPGG     P
Sbjct: 625 KGAAVGGGAGATAAGGGGGPGGGGGGGP 652


>gi|8922601 ADP-ribosylation factor-like 10C [Homo sapiens]
          Length = 186

 Score = 34.7 bits (78), Expect = 0.16
 Identities = 25/87 (28%), Positives = 42/87 (48%), Gaps = 11/87 (12%)

Query: 64  ILLMGLRRSGKSSIQKVVFHKMSPNETLFLESTN--KIYKDDISNSSFVNFQIWDFPGQM 121
           + L+GL+ SGK++   V+       + +     N  K+ K +++       +IWD  GQ 
Sbjct: 23  LTLVGLQYSGKTTFVNVIASGQFSEDMIPTVGFNMRKVTKGNVT------IKIWDIGGQP 76

Query: 122 DFFDPTFDYEMIFRGTGALIYVIDAQD 148
            F      +E   RG  A++Y+IDA D
Sbjct: 77  RFRSM---WERYCRGVNAIVYMIDAAD 100


>gi|229577180 MPN domain containing isoform 2 [Homo sapiens]
          Length = 451

 Score = 34.3 bits (77), Expect = 0.20
 Identities = 23/68 (33%), Positives = 30/68 (44%), Gaps = 17/68 (25%)

Query: 7  AEETPLAGSYGAADSFPKDFGYGVEEEEEE-----------------AAAAGGGVGAGAG 49
          A   PL+ + GA +  P++     E E+ E                  +  GGG GAGAG
Sbjct: 2  AAPEPLSPAGGAGEEAPEEDEDEAEAEDPERPNAGAGGGRSGGGGSSVSGGGGGGGAGAG 61

Query: 50 GGCGPGGA 57
          G  GPGGA
Sbjct: 62 GCGGPGGA 69


>gi|31542699 MPN domain containing isoform 1 [Homo sapiens]
          Length = 471

 Score = 34.3 bits (77), Expect = 0.20
 Identities = 23/68 (33%), Positives = 30/68 (44%), Gaps = 17/68 (25%)

Query: 7  AEETPLAGSYGAADSFPKDFGYGVEEEEEE-----------------AAAAGGGVGAGAG 49
          A   PL+ + GA +  P++     E E+ E                  +  GGG GAGAG
Sbjct: 2  AAPEPLSPAGGAGEEAPEEDEDEAEAEDPERPNAGAGGGRSGGGGSSVSGGGGGGGAGAG 61

Query: 50 GGCGPGGA 57
          G  GPGGA
Sbjct: 62 GCGGPGGA 69


>gi|19923262 RAB5A, member RAS oncogene family [Homo sapiens]
          Length = 215

 Score = 34.3 bits (77), Expect = 0.20
 Identities = 48/201 (23%), Positives = 81/201 (40%), Gaps = 25/201 (12%)

Query: 50  GGCGPGGADSSKP----RILLMGLRRSGKSSIQ----KVVFHKMSPNETLFLESTNKIYK 101
           G   P G ++       +++L+G    GKSS+     K  FH+   +       T  +  
Sbjct: 5   GATRPNGPNTGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCL 64

Query: 102 DDISNSSFVNFQIWDFPGQMDFFDPTFDYEMIFRGTGALIYVIDAQDDYMEALTRLHITV 161
           DD +    V F+IWD  GQ  +        M +RG  A I V D  ++  E+  R    V
Sbjct: 65  DDTT----VKFEIWDTAGQERYHSLA---PMYYRGAQAAIVVYDITNE--ESFARAKNWV 115

Query: 162 SKAYK-VNPDMNFEVFIHKVDGLSDDHKIETQRDIHQRANDDLADAGLEKLHLSFYLTSI 220
            +  +  +P++   +  +K D       +  +R +  +     AD        +   TS+
Sbjct: 116 KELQRQASPNIVIALSGNKAD-------LANKRAVDFQEAQSYADDNSLLFMETSAKTSM 168

Query: 221 YDHSIFEAFSKVVQKLIPQLP 241
             + IF A +K + K  PQ P
Sbjct: 169 NVNEIFMAIAKKLPKNEPQNP 189


>gi|66879664 ADP-ribosylation factor 1 [Homo sapiens]
          Length = 181

 Score = 34.3 bits (77), Expect = 0.20
 Identities = 25/86 (29%), Positives = 45/86 (52%), Gaps = 8/86 (9%)

Query: 63  RILLMGLRRSGKSSIQKVVFHKMSPNETLFLESTNKIYKDDISNSSFVNFQIWDFPGQMD 122
           RIL++GL  +GK++I     +K+   E +    T     + +   + ++F +WD  GQ D
Sbjct: 19  RILMVGLDAAGKTTI----LYKLKLGEIVTTIPTIGFNVETVEYKN-ISFTVWDVGGQ-D 72

Query: 123 FFDPTFDYEMIFRGTGALIYVIDAQD 148
              P + +   F+ T  LI+V+D+ D
Sbjct: 73  KIRPLWRH--YFQNTQGLIFVVDSND 96


>gi|66879662 ADP-ribosylation factor 1 [Homo sapiens]
          Length = 181

 Score = 34.3 bits (77), Expect = 0.20
 Identities = 25/86 (29%), Positives = 45/86 (52%), Gaps = 8/86 (9%)

Query: 63  RILLMGLRRSGKSSIQKVVFHKMSPNETLFLESTNKIYKDDISNSSFVNFQIWDFPGQMD 122
           RIL++GL  +GK++I     +K+   E +    T     + +   + ++F +WD  GQ D
Sbjct: 19  RILMVGLDAAGKTTI----LYKLKLGEIVTTIPTIGFNVETVEYKN-ISFTVWDVGGQ-D 72

Query: 123 FFDPTFDYEMIFRGTGALIYVIDAQD 148
              P + +   F+ T  LI+V+D+ D
Sbjct: 73  KIRPLWRH--YFQNTQGLIFVVDSND 96


>gi|66879660 ADP-ribosylation factor 1 [Homo sapiens]
          Length = 181

 Score = 34.3 bits (77), Expect = 0.20
 Identities = 25/86 (29%), Positives = 45/86 (52%), Gaps = 8/86 (9%)

Query: 63  RILLMGLRRSGKSSIQKVVFHKMSPNETLFLESTNKIYKDDISNSSFVNFQIWDFPGQMD 122
           RIL++GL  +GK++I     +K+   E +    T     + +   + ++F +WD  GQ D
Sbjct: 19  RILMVGLDAAGKTTI----LYKLKLGEIVTTIPTIGFNVETVEYKN-ISFTVWDVGGQ-D 72

Query: 123 FFDPTFDYEMIFRGTGALIYVIDAQD 148
              P + +   F+ T  LI+V+D+ D
Sbjct: 73  KIRPLWRH--YFQNTQGLIFVVDSND 96


>gi|4502201 ADP-ribosylation factor 1 [Homo sapiens]
          Length = 181

 Score = 34.3 bits (77), Expect = 0.20
 Identities = 25/86 (29%), Positives = 45/86 (52%), Gaps = 8/86 (9%)

Query: 63  RILLMGLRRSGKSSIQKVVFHKMSPNETLFLESTNKIYKDDISNSSFVNFQIWDFPGQMD 122
           RIL++GL  +GK++I     +K+   E +    T     + +   + ++F +WD  GQ D
Sbjct: 19  RILMVGLDAAGKTTI----LYKLKLGEIVTTIPTIGFNVETVEYKN-ISFTVWDVGGQ-D 72

Query: 123 FFDPTFDYEMIFRGTGALIYVIDAQD 148
              P + +   F+ T  LI+V+D+ D
Sbjct: 73  KIRPLWRH--YFQNTQGLIFVVDSND 96


>gi|4502203 ADP-ribosylation factor 3 [Homo sapiens]
          Length = 181

 Score = 34.3 bits (77), Expect = 0.20
 Identities = 25/86 (29%), Positives = 45/86 (52%), Gaps = 8/86 (9%)

Query: 63  RILLMGLRRSGKSSIQKVVFHKMSPNETLFLESTNKIYKDDISNSSFVNFQIWDFPGQMD 122
           RIL++GL  +GK++I     +K+   E +    T     + +   + ++F +WD  GQ D
Sbjct: 19  RILMVGLDAAGKTTI----LYKLKLGEIVTTIPTIGFNVETVEYKN-ISFTVWDVGGQ-D 72

Query: 123 FFDPTFDYEMIFRGTGALIYVIDAQD 148
              P + +   F+ T  LI+V+D+ D
Sbjct: 73  KIRPLWRH--YFQNTQGLIFVVDSND 96


>gi|5174607 NGFI-A binding protein 2 [Homo sapiens]
          Length = 525

 Score = 34.3 bits (77), Expect = 0.20
 Identities = 31/82 (37%), Positives = 39/82 (47%), Gaps = 18/82 (21%)

Query: 3   LQYGAEETPLAGSYGAAD-------SFPK-DFGYGVEEEEEE---AAAAGGGVGAGAG-- 49
           L+ G + +PL G  GA D       S P+ D G G EEE      +  AGGGV  G G  
Sbjct: 164 LELGEKLSPLPGGPGAGDPRIWPGRSTPESDVGAGGEEEAGSPPFSPPAGGGVPEGTGAG 223

Query: 50  ----GGCGPGGADSSKPRILLM 67
               GG G GG D  +P ++ M
Sbjct: 224 GLAAGGTG-GGPDRLEPEMVRM 244


>gi|38787935 BMP-2 inducible kinase isoform a [Homo sapiens]
          Length = 1161

 Score = 33.9 bits (76), Expect = 0.27
 Identities = 14/20 (70%), Positives = 15/20 (75%)

Query: 38 AAAGGGVGAGAGGGCGPGGA 57
          AA GG  GAGAG GCG GG+
Sbjct: 18 AAGGGAGGAGAGAGCGSGGS 37


>gi|38787904 BMP-2 inducible kinase isoform b [Homo sapiens]
          Length = 662

 Score = 33.9 bits (76), Expect = 0.27
 Identities = 14/20 (70%), Positives = 15/20 (75%)

Query: 38 AAAGGGVGAGAGGGCGPGGA 57
          AA GG  GAGAG GCG GG+
Sbjct: 18 AAGGGAGGAGAGAGCGSGGS 37


>gi|51702521 POU domain, class 3, transcription factor 2 [Homo
          sapiens]
          Length = 443

 Score = 33.9 bits (76), Expect = 0.27
 Identities = 20/58 (34%), Positives = 24/58 (41%), Gaps = 2/58 (3%)

Query: 5  YGAEETPLAGSYGAADS--FPKDFGYGVEEEEEEAAAAGGGVGAGAGGGCGPGGADSS 60
          Y   ++ + G YGA  S   P    +            GGG G G GGG G GG D S
Sbjct: 34 YREAQSLVQGDYGALQSNGHPLSHAHQWITALSHGGGGGGGGGGGGGGGGGGGGGDGS 91


>gi|34486092 adenylate cyclase 5 [Homo sapiens]
          Length = 1261

 Score = 33.9 bits (76), Expect = 0.27
 Identities = 21/71 (29%), Positives = 30/71 (42%), Gaps = 8/71 (11%)

Query: 6   GAEETPLAGSYGAADSFPKDFGYGVEE--------EEEEAAAAGGGVGAGAGGGCGPGGA 57
           G      A S G  +  P+    G+EE        +E EA A  GG G+G GG     G+
Sbjct: 136 GGGSAAAAASAGGTEVRPRSVEVGLEERRGKGRAADELEAGAVEGGEGSGDGGSSADSGS 195

Query: 58  DSSKPRILLMG 68
            +    +L +G
Sbjct: 196 GAGPGAVLSLG 206


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.137    0.398 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,975,132
Number of Sequences: 37866
Number of extensions: 695584
Number of successful extensions: 7307
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 109
Number of HSP's successfully gapped in prelim test: 97
Number of HSP's that attempted gapping in prelim test: 5535
Number of HSP's gapped (non-prelim): 1272
length of query: 399
length of database: 18,247,518
effective HSP length: 104
effective length of query: 295
effective length of database: 14,309,454
effective search space: 4221288930
effective search space used: 4221288930
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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