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Search of human proteins with 119703749
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|119703749 hydrocephalus inducing isoform a [Homo sapiens]
(5120 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|119703749 hydrocephalus inducing isoform a [Homo sapiens] 1.029e+04 0.0
gi|46361983 hydrocephalus inducing isoform b [Homo sapiens] 2055 0.0
gi|90669228 deleted in lung and esophageal cancer 1 isoform DLEC... 118 1e-25
gi|90669194 deleted in lung and esophageal cancer 1 isoform DLEC... 118 1e-25
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 80 5e-14
gi|148746195 trichohyalin [Homo sapiens] 80 5e-14
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 75 2e-12
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 74 4e-12
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 74 4e-12
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 72 1e-11
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 71 3e-11
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 70 5e-11
gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 70 7e-11
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 66 1e-09
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 66 1e-09
gi|15149465 caldesmon 1 isoform 5 [Homo sapiens] 65 1e-09
gi|4826657 caldesmon 1 isoform 2 [Homo sapiens] 65 1e-09
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 65 2e-09
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 65 2e-09
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 65 2e-09
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 64 3e-09
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 63 7e-09
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 63 7e-09
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 63 7e-09
gi|22758136 MAP7 domain containing 2 [Homo sapiens] 62 1e-08
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 62 2e-08
gi|83035129 coiled-coil domain containing 108 isoform 1 [Homo sa... 61 3e-08
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 60 4e-08
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 60 4e-08
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 60 4e-08
>gi|119703749 hydrocephalus inducing isoform a [Homo sapiens]
Length = 5120
Score = 1.029e+04 bits (26703), Expect = 0.0
Identities = 5120/5120 (100%), Positives = 5120/5120 (100%)
Query: 1 MTSRRLEESMGAVQMGLVNMFKGFQSKVLPPLSPKVVTEEEVNRMLTPSEFLKEMSLTTE 60
MTSRRLEESMGAVQMGLVNMFKGFQSKVLPPLSPKVVTEEEVNRMLTPSEFLKEMSLTTE
Sbjct: 1 MTSRRLEESMGAVQMGLVNMFKGFQSKVLPPLSPKVVTEEEVNRMLTPSEFLKEMSLTTE 60
Query: 61 QRLAKTRLMCRPQIIELLDMGETTHQKFSGIDLDQALFQPFPSEIIFQNYTPCEVYEVPL 120
QRLAKTRLMCRPQIIELLDMGETTHQKFSGIDLDQALFQPFPSEIIFQNYTPCEVYEVPL
Sbjct: 61 QRLAKTRLMCRPQIIELLDMGETTHQKFSGIDLDQALFQPFPSEIIFQNYTPCEVYEVPL 120
Query: 121 ILRNNDKIPRLVKVVEESSPYFKVISPKDIGHKVAPGVPSIFRILFTPEENKDYAHTLTC 180
ILRNNDKIPRLVKVVEESSPYFKVISPKDIGHKVAPGVPSIFRILFTPEENKDYAHTLTC
Sbjct: 121 ILRNNDKIPRLVKVVEESSPYFKVISPKDIGHKVAPGVPSIFRILFTPEENKDYAHTLTC 180
Query: 181 VTEREKFIVPIKARGARAILDFPDKLNFSTCPVKYSTQKILLVRNIGNKNAVFHIKTCRP 240
VTEREKFIVPIKARGARAILDFPDKLNFSTCPVKYSTQKILLVRNIGNKNAVFHIKTCRP
Sbjct: 181 VTEREKFIVPIKARGARAILDFPDKLNFSTCPVKYSTQKILLVRNIGNKNAVFHIKTCRP 240
Query: 241 FSIEPAIGTLNVGESMQLEVEFEPQSVGDHSGRLIVCYDTGEKVFVSLYGAAIDMNIRLD 300
FSIEPAIGTLNVGESMQLEVEFEPQSVGDHSGRLIVCYDTGEKVFVSLYGAAIDMNIRLD
Sbjct: 241 FSIEPAIGTLNVGESMQLEVEFEPQSVGDHSGRLIVCYDTGEKVFVSLYGAAIDMNIRLD 300
Query: 301 KNSLTIEKTYISLANQRTITIHNRSNIIAHFLWKVFATQQEEDREKYRACDDLIKEEKDE 360
KNSLTIEKTYISLANQRTITIHNRSNIIAHFLWKVFATQQEEDREKYRACDDLIKEEKDE
Sbjct: 301 KNSLTIEKTYISLANQRTITIHNRSNIIAHFLWKVFATQQEEDREKYRACDDLIKEEKDE 360
Query: 361 TDEFFEECITDPLLREHLSVLSRTFANQRRLVQGDSKLFFNNVFTVEPLEGDVWPNSSAE 420
TDEFFEECITDPLLREHLSVLSRTFANQRRLVQGDSKLFFNNVFTVEPLEGDVWPNSSAE
Sbjct: 361 TDEFFEECITDPLLREHLSVLSRTFANQRRLVQGDSKLFFNNVFTVEPLEGDVWPNSSAE 420
Query: 421 ITVYFNPLEAKLYQQTIYCDILGREIRLPLRIKGEGMGPKIHFNFELLDIGKVFTGSAHC 480
ITVYFNPLEAKLYQQTIYCDILGREIRLPLRIKGEGMGPKIHFNFELLDIGKVFTGSAHC
Sbjct: 421 ITVYFNPLEAKLYQQTIYCDILGREIRLPLRIKGEGMGPKIHFNFELLDIGKVFTGSAHC 480
Query: 481 YEAILYNKGSIDALFNMTPPTSALGACFVFSPKEGIIEPSGVQAIQISFSSTILGNFEEE 540
YEAILYNKGSIDALFNMTPPTSALGACFVFSPKEGIIEPSGVQAIQISFSSTILGNFEEE
Sbjct: 481 YEAILYNKGSIDALFNMTPPTSALGACFVFSPKEGIIEPSGVQAIQISFSSTILGNFEEE 540
Query: 541 FLVNVNGSPEPVKLTIRGCVIGPTFHFNVPALHFGDVSFGFPHTLICSLNNTSLIPMTYK 600
FLVNVNGSPEPVKLTIRGCVIGPTFHFNVPALHFGDVSFGFPHTLICSLNNTSLIPMTYK
Sbjct: 541 FLVNVNGSPEPVKLTIRGCVIGPTFHFNVPALHFGDVSFGFPHTLICSLNNTSLIPMTYK 600
Query: 601 LRIPGDGLGHKSISYCEQHVDYKRPSWTKEEISSMKPKEFTISPDCGTIRPQGFAAIRVT 660
LRIPGDGLGHKSISYCEQHVDYKRPSWTKEEISSMKPKEFTISPDCGTIRPQGFAAIRVT
Sbjct: 601 LRIPGDGLGHKSISYCEQHVDYKRPSWTKEEISSMKPKEFTISPDCGTIRPQGFAAIRVT 660
Query: 661 LCSNTVQKYELALVVDVEGIGEEVLALLITARCVVPALHLVNTEVDFGHCFLKYPYEKTL 720
LCSNTVQKYELALVVDVEGIGEEVLALLITARCVVPALHLVNTEVDFGHCFLKYPYEKTL
Sbjct: 661 LCSNTVQKYELALVVDVEGIGEEVLALLITARCVVPALHLVNTEVDFGHCFLKYPYEKTL 720
Query: 721 QLANQDDLPGFYEVQPQVCEEVPTVLFSSPTPSGVISPSSTIHIPLVLETQVTGEHRSTV 780
QLANQDDLPGFYEVQPQVCEEVPTVLFSSPTPSGVISPSSTIHIPLVLETQVTGEHRSTV
Sbjct: 721 QLANQDDLPGFYEVQPQVCEEVPTVLFSSPTPSGVISPSSTIHIPLVLETQVTGEHRSTV 780
Query: 781 YISIFGSQDPPLVCHLKSAGEGPVIYVHPNQVDFGNIYVLKDSSRILNLCNQSFIPAFFQ 840
YISIFGSQDPPLVCHLKSAGEGPVIYVHPNQVDFGNIYVLKDSSRILNLCNQSFIPAFFQ
Sbjct: 781 YISIFGSQDPPLVCHLKSAGEGPVIYVHPNQVDFGNIYVLKDSSRILNLCNQSFIPAFFQ 840
Query: 841 AHMAHKKSLWTIEPNEGMVPPETDVQLALTANLNDTLTFKDCVILDIENSSTYRIPVQAS 900
AHMAHKKSLWTIEPNEGMVPPETDVQLALTANLNDTLTFKDCVILDIENSSTYRIPVQAS
Sbjct: 841 AHMAHKKSLWTIEPNEGMVPPETDVQLALTANLNDTLTFKDCVILDIENSSTYRIPVQAS 900
Query: 901 GTGSTIVSDKPFAPELNLGAHFSLDTHYYHFKLINKGRRIQQLFWMNDSFRPQAKLSKKG 960
GTGSTIVSDKPFAPELNLGAHFSLDTHYYHFKLINKGRRIQQLFWMNDSFRPQAKLSKKG
Sbjct: 901 GTGSTIVSDKPFAPELNLGAHFSLDTHYYHFKLINKGRRIQQLFWMNDSFRPQAKLSKKG 960
Query: 961 RVKKGHAHVQPQPSGSQEPRDPQSPVFHLHPASMELYPGQAIDVILEGYSATPRIVKEKL 1020
RVKKGHAHVQPQPSGSQEPRDPQSPVFHLHPASMELYPGQAIDVILEGYSATPRIVKEKL
Sbjct: 961 RVKKGHAHVQPQPSGSQEPRDPQSPVFHLHPASMELYPGQAIDVILEGYSATPRIVKEKL 1020
Query: 1021 VCHAIIGAQKGKSLVMAVNITCEFVAPLIQLSTKQLIYRLEKKPNSILKPDYQPLAIKNI 1080
VCHAIIGAQKGKSLVMAVNITCEFVAPLIQLSTKQLIYRLEKKPNSILKPDYQPLAIKNI
Sbjct: 1021 VCHAIIGAQKGKSLVMAVNITCEFVAPLIQLSTKQLIYRLEKKPNSILKPDYQPLAIKNI 1080
Query: 1081 STLPVNLLLSTSGPFFICETDKSLLPATPEPIKLEIDEEKNLLIKFDPSYRNDLNNWVAE 1140
STLPVNLLLSTSGPFFICETDKSLLPATPEPIKLEIDEEKNLLIKFDPSYRNDLNNWVAE
Sbjct: 1081 STLPVNLLLSTSGPFFICETDKSLLPATPEPIKLEIDEEKNLLIKFDPSYRNDLNNWVAE 1140
Query: 1141 EILAIKYVEHPQIDSLDLRGEVHYPNLSFETKELDFGCILNDTELIRYVTITNCSPLVVK 1200
EILAIKYVEHPQIDSLDLRGEVHYPNLSFETKELDFGCILNDTELIRYVTITNCSPLVVK
Sbjct: 1141 EILAIKYVEHPQIDSLDLRGEVHYPNLSFETKELDFGCILNDTELIRYVTITNCSPLVVK 1200
Query: 1201 FRWFFLVNDEENQIRFVTLPKKPYSAPVSQMESIPATSEAASPPAILVTVESPEMDLNDF 1260
FRWFFLVNDEENQIRFVTLPKKPYSAPVSQMESIPATSEAASPPAILVTVESPEMDLNDF
Sbjct: 1201 FRWFFLVNDEENQIRFVTLPKKPYSAPVSQMESIPATSEAASPPAILVTVESPEMDLNDF 1260
Query: 1261 VKTVLVDEDARPEEKELRKTKASSVISDVRCPFHGEERIYSSQSQVEDQESLQTCEQNEM 1320
VKTVLVDEDARPEEKELRKTKASSVISDVRCPFHGEERIYSSQSQVEDQESLQTCEQNEM
Sbjct: 1261 VKTVLVDEDARPEEKELRKTKASSVISDVRCPFHGEERIYSSQSQVEDQESLQTCEQNEM 1320
Query: 1321 LSIGIEEVFDILPLFGVLQPHSSHQISFTFYGHANIIAQAKALCEVEEGPTYEITLKGEA 1380
LSIGIEEVFDILPLFGVLQPHSSHQISFTFYGHANIIAQAKALCEVEEGPTYEITLKGEA
Sbjct: 1321 LSIGIEEVFDILPLFGVLQPHSSHQISFTFYGHANIIAQAKALCEVEEGPTYEITLKGEA 1380
Query: 1381 SLVNYSFDTKDIHYGLQLFDHVTEREITLTNMGKVGFEFKVLTDHQSSPDNLLPGVPLIL 1440
SLVNYSFDTKDIHYGLQLFDHVTEREITLTNMGKVGFEFKVLTDHQSSPDNLLPGVPLIL
Sbjct: 1381 SLVNYSFDTKDIHYGLQLFDHVTEREITLTNMGKVGFEFKVLTDHQSSPDNLLPGVPLIL 1440
Query: 1441 PVSGFISSHQEQVLKVYYLPGVPEVFKRSFQIQIAHLDPENITLSGEGIFPQICLDLPRN 1500
PVSGFISSHQEQVLKVYYLPGVPEVFKRSFQIQIAHLDPENITLSGEGIFPQICLDLPRN
Sbjct: 1441 PVSGFISSHQEQVLKVYYLPGVPEVFKRSFQIQIAHLDPENITLSGEGIFPQICLDLPRN 1500
Query: 1501 LTANEKYEMFLNQARKNTDKEYNKCEMLDHFDIITEEVPEDEPAEVSAHLQMEVERLIVQ 1560
LTANEKYEMFLNQARKNTDKEYNKCEMLDHFDIITEEVPEDEPAEVSAHLQMEVERLIVQ
Sbjct: 1501 LTANEKYEMFLNQARKNTDKEYNKCEMLDHFDIITEEVPEDEPAEVSAHLQMEVERLIVQ 1560
Query: 1561 SYVLEHQKTTTPDPMDDPCFSHRSRRKLAKIQLPEYILDFGYIILGEVRTHIIKIINTSH 1620
SYVLEHQKTTTPDPMDDPCFSHRSRRKLAKIQLPEYILDFGYIILGEVRTHIIKIINTSH
Sbjct: 1561 SYVLEHQKTTTPDPMDDPCFSHRSRRKLAKIQLPEYILDFGYIILGEVRTHIIKIINTSH 1620
Query: 1621 FPVSFHADKRVLHETGFSTELDRVKNLPHCETEIFEVRFDPQGANLPVGSKEVILPIKVV 1680
FPVSFHADKRVLHETGFSTELDRVKNLPHCETEIFEVRFDPQGANLPVGSKEVILPIKVV
Sbjct: 1621 FPVSFHADKRVLHETGFSTELDRVKNLPHCETEIFEVRFDPQGANLPVGSKEVILPIKVV 1680
Query: 1681 GGPTVHICLQAKVTIPTMTLSRGKVDFATIQCGQCLVETIQLSNHLQVPCEWFVQSQKPV 1740
GGPTVHICLQAKVTIPTMTLSRGKVDFATIQCGQCLVETIQLSNHLQVPCEWFVQSQKPV
Sbjct: 1681 GGPTVHICLQAKVTIPTMTLSRGKVDFATIQCGQCLVETIQLSNHLQVPCEWFVQSQKPV 1740
Query: 1741 DKLEKHMPKYLRQKLRAELKPKTRIFEIQPISGVLDPGEKSNVQVKFMPKEEKFYSQTLV 1800
DKLEKHMPKYLRQKLRAELKPKTRIFEIQPISGVLDPGEKSNVQVKFMPKEEKFYSQTLV
Sbjct: 1741 DKLEKHMPKYLRQKLRAELKPKTRIFEIQPISGVLDPGEKSNVQVKFMPKEEKFYSQTLV 1800
Query: 1801 FQIAQSAQKLTLLARGQGLEPRLEFSPSVLDLGPLLLCAPGDEAEVIVKNPCNFPIEFYS 1860
FQIAQSAQKLTLLARGQGLEPRLEFSPSVLDLGPLLLCAPGDEAEVIVKNPCNFPIEFYS
Sbjct: 1801 FQIAQSAQKLTLLARGQGLEPRLEFSPSVLDLGPLLLCAPGDEAEVIVKNPCNFPIEFYS 1860
Query: 1861 LEFDQQYLIEEKILRKLKGYDSYNTLLLPPRNPGEKLPPELYEYFKEIKKSKEEQMRAKY 1920
LEFDQQYLIEEKILRKLKGYDSYNTLLLPPRNPGEKLPPELYEYFKEIKKSKEEQMRAKY
Sbjct: 1861 LEFDQQYLIEEKILRKLKGYDSYNTLLLPPRNPGEKLPPELYEYFKEIKKSKEEQMRAKY 1920
Query: 1921 LENLAQENEEEDITSSDQGTSNSTKRTSLSRGISVTSNLEEWHALLVESKTYLEEEEDEE 1980
LENLAQENEEEDITSSDQGTSNSTKRTSLSRGISVTSNLEEWHALLVESKTYLEEEEDEE
Sbjct: 1921 LENLAQENEEEDITSSDQGTSNSTKRTSLSRGISVTSNLEEWHALLVESKTYLEEEEDEE 1980
Query: 1981 SLEKIIFQTDKLQSIDSHSMEEVGEVENNPVSKAIARHLGIDISAEGRLAKNRKGIAIII 2040
SLEKIIFQTDKLQSIDSHSMEEVGEVENNPVSKAIARHLGIDISAEGRLAKNRKGIAIII
Sbjct: 1981 SLEKIIFQTDKLQSIDSHSMEEVGEVENNPVSKAIARHLGIDISAEGRLAKNRKGIAIII 2040
Query: 2041 HGTPLSGKSANAVSVAKYYNAACLSIDSIVLEAVANSNNIPGIRARELCIRAAIEQSVKE 2100
HGTPLSGKSANAVSVAKYYNAACLSIDSIVLEAVANSNNIPGIRARELCIRAAIEQSVKE
Sbjct: 2041 HGTPLSGKSANAVSVAKYYNAACLSIDSIVLEAVANSNNIPGIRARELCIRAAIEQSVKE 2100
Query: 2101 GEEAAQEAAVGQNVIGQGRLSTDTLGKLASEMTLVAPEIKPGKSVRGSVVITKSKADSHG 2160
GEEAAQEAAVGQNVIGQGRLSTDTLGKLASEMTLVAPEIKPGKSVRGSVVITKSKADSHG
Sbjct: 2101 GEEAAQEAAVGQNVIGQGRLSTDTLGKLASEMTLVAPEIKPGKSVRGSVVITKSKADSHG 2160
Query: 2161 SGSQKQHHSHQSETPQISSSPLPPGPIHRWLSVSPSVGGETGLMSCVLPDELLVQILAER 2220
SGSQKQHHSHQSETPQISSSPLPPGPIHRWLSVSPSVGGETGLMSCVLPDELLVQILAER
Sbjct: 2161 SGSQKQHHSHQSETPQISSSPLPPGPIHRWLSVSPSVGGETGLMSCVLPDELLVQILAER 2220
Query: 2221 IQLSDCYRGVVFDGLDTLFAQNAAAALLCLLKAIGSREHIYILNMAQDYAAMKAQEKAKK 2280
IQLSDCYRGVVFDGLDTLFAQNAAAALLCLLKAIGSREHIYILNMAQDYAAMKAQEKAKK
Sbjct: 2221 IQLSDCYRGVVFDGLDTLFAQNAAAALLCLLKAIGSREHIYILNMAQDYAAMKAQEKAKK 2280
Query: 2281 EQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKREQERLAKEM 2340
EQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKREQERLAKEM
Sbjct: 2281 EQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKREQERLAKEM 2340
Query: 2341 QEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKVDVKMETIE 2400
QEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKVDVKMETIE
Sbjct: 2341 QEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKVDVKMETIE 2400
Query: 2401 RKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQLAPKFKTYE 2460
RKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQLAPKFKTYE
Sbjct: 2401 RKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQLAPKFKTYE 2460
Query: 2461 LTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRERERLEKERT 2520
LTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRERERLEKERT
Sbjct: 2461 LTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRERERLEKERT 2520
Query: 2521 EKERLEREKAERERLEKLRALEERSDWEGEGEEDHEGKKEKDLGVPFLDIQTPDFEGLSW 2580
EKERLEREKAERERLEKLRALEERSDWEGEGEEDHEGKKEKDLGVPFLDIQTPDFEGLSW
Sbjct: 2521 EKERLEREKAERERLEKLRALEERSDWEGEGEEDHEGKKEKDLGVPFLDIQTPDFEGLSW 2580
Query: 2581 KQALESDKLPKGEQILDILGLGASGPPIPPPALFSIVSYPVKRPPLTMTDDLEHFVFVIP 2640
KQALESDKLPKGEQILDILGLGASGPPIPPPALFSIVSYPVKRPPLTMTDDLEHFVFVIP
Sbjct: 2581 KQALESDKLPKGEQILDILGLGASGPPIPPPALFSIVSYPVKRPPLTMTDDLEHFVFVIP 2640
Query: 2641 PSEDISLDEKKEMEIESDFLATTNTTKAQEEQTSSSKGGKQKMKEKIDQVFEIQKDKRHM 2700
PSEDISLDEKKEMEIESDFLATTNTTKAQEEQTSSSKGGKQKMKEKIDQVFEIQKDKRHM
Sbjct: 2641 PSEDISLDEKKEMEIESDFLATTNTTKAQEEQTSSSKGGKQKMKEKIDQVFEIQKDKRHM 2700
Query: 2701 ALNRKVLSGEPAGTISQLSDTDLDNFNGQHSQEKFTRLNHFRWIVPANGEVTLQVHFSSD 2760
ALNRKVLSGEPAGTISQLSDTDLDNFNGQHSQEKFTRLNHFRWIVPANGEVTLQVHFSSD
Sbjct: 2701 ALNRKVLSGEPAGTISQLSDTDLDNFNGQHSQEKFTRLNHFRWIVPANGEVTLQVHFSSD 2760
Query: 2761 EFGNFDQTFNFEILGTCCQYQLYCRGICTYPYICQDPKVVFPQRKMDMKTNEVIFKKYVM 2820
EFGNFDQTFNFEILGTCCQYQLYCRGICTYPYICQDPKVVFPQRKMDMKTNEVIFKKYVM
Sbjct: 2761 EFGNFDQTFNFEILGTCCQYQLYCRGICTYPYICQDPKVVFPQRKMDMKTNEVIFKKYVM 2820
Query: 2821 STETYYFGPLLCGKSRDKYKSSLFPGNMETLTILNTSLMVVEASFYFQNDVKANTYFLEP 2880
STETYYFGPLLCGKSRDKYKSSLFPGNMETLTILNTSLMVVEASFYFQNDVKANTYFLEP
Sbjct: 2821 STETYYFGPLLCGKSRDKYKSSLFPGNMETLTILNTSLMVVEASFYFQNDVKANTYFLEP 2880
Query: 2881 NTMVLKPNEKQILNVWAYPTSVGVFEDSIVCCINDNPEPAIFQLSCQGIRPELELEPRQL 2940
NTMVLKPNEKQILNVWAYPTSVGVFEDSIVCCINDNPEPAIFQLSCQGIRPELELEPRQL
Sbjct: 2881 NTMVLKPNEKQILNVWAYPTSVGVFEDSIVCCINDNPEPAIFQLSCQGIRPELELEPRQL 2940
Query: 2941 HFDRLLLHRQESRVVLLRNVTLLPVAWRITSLEHLGDDFTVSLMQGTIPPEAEYGLHLYF 3000
HFDRLLLHRQESRVVLLRNVTLLPVAWRITSLEHLGDDFTVSLMQGTIPPEAEYGLHLYF
Sbjct: 2941 HFDRLLLHRQESRVVLLRNVTLLPVAWRITSLEHLGDDFTVSLMQGTIPPEAEYGLHLYF 3000
Query: 3001 QPTKPVNIKKAIRLEVLDAENLLGVVQIENIMVFAEAYDIALDITFPKGAEGGLDFGIVR 3060
QPTKPVNIKKAIRLEVLDAENLLGVVQIENIMVFAEAYDIALDITFPKGAEGGLDFGIVR
Sbjct: 3001 QPTKPVNIKKAIRLEVLDAENLLGVVQIENIMVFAEAYDIALDITFPKGAEGGLDFGIVR 3060
Query: 3061 VTEEAKQPLQLKNRGKYEIAFSFSVDSVGISTPNINSMISVQPKKGSLTPTEKPTNVQVF 3120
VTEEAKQPLQLKNRGKYEIAFSFSVDSVGISTPNINSMISVQPKKGSLTPTEKPTNVQVF
Sbjct: 3061 VTEEAKQPLQLKNRGKYEIAFSFSVDSVGISTPNINSMISVQPKKGSLTPTEKPTNVQVF 3120
Query: 3121 FHAKKEVKIEHQPVLRCQIIEPNISEGGEIIASIPIKFSANAVYSKYNITPSSVINFGAL 3180
FHAKKEVKIEHQPVLRCQIIEPNISEGGEIIASIPIKFSANAVYSKYNITPSSVINFGAL
Sbjct: 3121 FHAKKEVKIEHQPVLRCQIIEPNISEGGEIIASIPIKFSANAVYSKYNITPSSVINFGAL 3180
Query: 3181 ICGTRKSTTFTIENQGVTDFKFALYKLTGESPIHQKKAASHVRHARSRESESFYKTGSSR 3240
ICGTRKSTTFTIENQGVTDFKFALYKLTGESPIHQKKAASHVRHARSRESESFYKTGSSR
Sbjct: 3181 ICGTRKSTTFTIENQGVTDFKFALYKLTGESPIHQKKAASHVRHARSRESESFYKTGSSR 3240
Query: 3241 AAKFSDTIQKEVTTTGQARFAHGMFTVYPGFGSIPSGGQQVINVDCVADAMGKCEEFIAI 3300
AAKFSDTIQKEVTTTGQARFAHGMFTVYPGFGSIPSGGQQVINVDCVADAMGKCEEFIAI
Sbjct: 3241 AAKFSDTIQKEVTTTGQARFAHGMFTVYPGFGSIPSGGQQVINVDCVADAMGKCEEFIAI 3300
Query: 3301 DISGRDPAVHPAGILYTLLAEACLPAFVTENNALIFEEHQICTSANLHHILQTIESGGLF 3360
DISGRDPAVHPAGILYTLLAEACLPAFVTENNALIFEEHQICTSANLHHILQTIESGGLF
Sbjct: 3301 DISGRDPAVHPAGILYTLLAEACLPAFVTENNALIFEEHQICTSANLHHILQTIESGGLF 3360
Query: 3361 VEDENKFIFCNVLVGRQAKARFKISNVGKITCDVNIVVRPISNKPFARIVDIFEVEPSKM 3420
VEDENKFIFCNVLVGRQAKARFKISNVGKITCDVNIVVRPISNKPFARIVDIFEVEPSKM
Sbjct: 3361 VEDENKFIFCNVLVGRQAKARFKISNVGKITCDVNIVVRPISNKPFARIVDIFEVEPSKM 3420
Query: 3421 CIASHSHAFATVSFTPQIMQNYQCIFEATLDGLPSTLAKSRGLVFDIAGEGNLPRVTVVR 3480
CIASHSHAFATVSFTPQIMQNYQCIFEATLDGLPSTLAKSRGLVFDIAGEGNLPRVTVVR
Sbjct: 3421 CIASHSHAFATVSFTPQIMQNYQCIFEATLDGLPSTLAKSRGLVFDIAGEGNLPRVTVVR 3480
Query: 3481 PVLHNQYGNPLLLFKRLLLGHSEKLPLILKNNGVLPAQLHVDLQDELGVFSLKGRPTTAY 3540
PVLHNQYGNPLLLFKRLLLGHSEKLPLILKNNGVLPAQLHVDLQDELGVFSLKGRPTTAY
Sbjct: 3481 PVLHNQYGNPLLLFKRLLLGHSEKLPLILKNNGVLPAQLHVDLQDELGVFSLKGRPTTAY 3540
Query: 3541 IYITEENKPHVKAKKAHTASLVVSPGDTAEFDVVFHSQKVGRMRGIIHLSVINNQYEETS 3600
IYITEENKPHVKAKKAHTASLVVSPGDTAEFDVVFHSQKVGRMRGIIHLSVINNQYEETS
Sbjct: 3541 IYITEENKPHVKAKKAHTASLVVSPGDTAEFDVVFHSQKVGRMRGIIHLSVINNQYEETS 3600
Query: 3601 IHMVGEGYEDDITLDNIHGLVAPTSQEDISISEFTEIIEDNDMEDLVAAALVDHIQFGDC 3660
IHMVGEGYEDDITLDNIHGLVAPTSQEDISISEFTEIIEDNDMEDLVAAALVDHIQFGDC
Sbjct: 3601 IHMVGEGYEDDITLDNIHGLVAPTSQEDISISEFTEIIEDNDMEDLVAAALVDHIQFGDC 3660
Query: 3661 HIGHSYNASFTVTNHSQVNLIRFEWPVSATIAFSPQMGHLHPGCAKDIVVTMKSDVPINL 3720
HIGHSYNASFTVTNHSQVNLIRFEWPVSATIAFSPQMGHLHPGCAKDIVVTMKSDVPINL
Sbjct: 3661 HIGHSYNASFTVTNHSQVNLIRFEWPVSATIAFSPQMGHLHPGCAKDIVVTMKSDVPINL 3720
Query: 3721 KNMRIRCKLSRIMFQLPADQVPDWDDRMHTVKWVDVPRNMPGTFTTKRKVIETDPEPAHS 3780
KNMRIRCKLSRIMFQLPADQVPDWDDRMHTVKWVDVPRNMPGTFTTKRKVIETDPEPAHS
Sbjct: 3721 KNMRIRCKLSRIMFQLPADQVPDWDDRMHTVKWVDVPRNMPGTFTTKRKVIETDPEPAHS 3780
Query: 3781 VLEENYQELQLQISANVDFASYHCQARDVRFKETLVYQTRVFEFDVINSGRVQLEFSWVS 3840
VLEENYQELQLQISANVDFASYHCQARDVRFKETLVYQTRVFEFDVINSGRVQLEFSWVS
Sbjct: 3781 VLEENYQELQLQISANVDFASYHCQARDVRFKETLVYQTRVFEFDVINSGRVQLEFSWVS 3840
Query: 3841 EDTSKAVSFAKPDHQGSAQKDQLSQGTMHTGSTLDSTMDHWAEGSPQPFSVEPSSGIVPV 3900
EDTSKAVSFAKPDHQGSAQKDQLSQGTMHTGSTLDSTMDHWAEGSPQPFSVEPSSGIVPV
Sbjct: 3841 EDTSKAVSFAKPDHQGSAQKDQLSQGTMHTGSTLDSTMDHWAEGSPQPFSVEPSSGIVPV 3900
Query: 3901 GKIQKFKVKFSPLDIGDFESNLFCQIPNLPPGEQGPVLVAKGRSTLPICHFDLKDSDYIS 3960
GKIQKFKVKFSPLDIGDFESNLFCQIPNLPPGEQGPVLVAKGRSTLPICHFDLKDSDYIS
Sbjct: 3901 GKIQKFKVKFSPLDIGDFESNLFCQIPNLPPGEQGPVLVAKGRSTLPICHFDLKDSDYIS 3960
Query: 3961 GHQRNPELRGSSGGALDPNTRVIEFTTVGIGGKNLRTFTILNPTNSTYSFCWISEEIESL 4020
GHQRNPELRGSSGGALDPNTRVIEFTTVGIGGKNLRTFTILNPTNSTYSFCWISEEIESL
Sbjct: 3961 GHQRNPELRGSSGGALDPNTRVIEFTTVGIGGKNLRTFTILNPTNSTYSFCWISEEIESL 4020
Query: 4021 QNPAAFTCLTEKGFIHPEKKAEIVFQFTPFHLGITESSWTFLIPEHNITVPFLLVGKTTE 4080
QNPAAFTCLTEKGFIHPEKKAEIVFQFTPFHLGITESSWTFLIPEHNITVPFLLVGKTTE
Sbjct: 4021 QNPAAFTCLTEKGFIHPEKKAEIVFQFTPFHLGITESSWTFLIPEHNITVPFLLVGKTTE 4080
Query: 4081 PLISLNKSHLNFSSLLIGREARETVQIINKEEQGFDFSFQDNSRYSEGFSNSLLVCPMEG 4140
PLISLNKSHLNFSSLLIGREARETVQIINKEEQGFDFSFQDNSRYSEGFSNSLLVCPMEG
Sbjct: 4081 PLISLNKSHLNFSSLLIGREARETVQIINKEEQGFDFSFQDNSRYSEGFSNSLLVCPMEG 4140
Query: 4141 WIPPLSRFPIDIFFTPKQEGDVNFNLICNVEKKVHPVTLNVKAEGYTMNVEIKCKDRTGS 4200
WIPPLSRFPIDIFFTPKQEGDVNFNLICNVEKKVHPVTLNVKAEGYTMNVEIKCKDRTGS
Sbjct: 4141 WIPPLSRFPIDIFFTPKQEGDVNFNLICNVEKKVHPVTLNVKAEGYTMNVEIKCKDRTGS 4200
Query: 4201 ITLLTPNQTNIINFYEVELNECVQCEFNFINTGKFTFSFQAQLCGSKTLLQYLEFSPIDS 4260
ITLLTPNQTNIINFYEVELNECVQCEFNFINTGKFTFSFQAQLCGSKTLLQYLEFSPIDS
Sbjct: 4201 ITLLTPNQTNIINFYEVELNECVQCEFNFINTGKFTFSFQAQLCGSKTLLQYLEFSPIDS 4260
Query: 4261 TVDVGQSVHATLSFQPLKKCVLTDLELIIKISHGPTFMCNISGCAVSPAIHFSFTSYNFG 4320
TVDVGQSVHATLSFQPLKKCVLTDLELIIKISHGPTFMCNISGCAVSPAIHFSFTSYNFG
Sbjct: 4261 TVDVGQSVHATLSFQPLKKCVLTDLELIIKISHGPTFMCNISGCAVSPAIHFSFTSYNFG 4320
Query: 4321 TCFIYQAGMPPYKQTLVITNKEETPMSIDCLYTNTTHLEVNSRVDVVKPGNTLEIPITFY 4380
TCFIYQAGMPPYKQTLVITNKEETPMSIDCLYTNTTHLEVNSRVDVVKPGNTLEIPITFY
Sbjct: 4321 TCFIYQAGMPPYKQTLVITNKEETPMSIDCLYTNTTHLEVNSRVDVVKPGNTLEIPITFY 4380
Query: 4381 PRESINYQELIPFEINGLSQQTVEIKGKGTKMKILVLDPANRIVKLGAVLPGQVVKRTVS 4440
PRESINYQELIPFEINGLSQQTVEIKGKGTKMKILVLDPANRIVKLGAVLPGQVVKRTVS
Sbjct: 4381 PRESINYQELIPFEINGLSQQTVEIKGKGTKMKILVLDPANRIVKLGAVLPGQVVKRTVS 4440
Query: 4441 IMNNSLAQLTFNQSILFTIPELQEPKVLTLAPFHNITLKPKEVCKLEVIFAPKKRVPPFS 4500
IMNNSLAQLTFNQSILFTIPELQEPKVLTLAPFHNITLKPKEVCKLEVIFAPKKRVPPFS
Sbjct: 4441 IMNNSLAQLTFNQSILFTIPELQEPKVLTLAPFHNITLKPKEVCKLEVIFAPKKRVPPFS 4500
Query: 4501 EEVFMECMGLLRPLFLLSGCCQALEISLDQEHIPFGPVVYQTQATRRILMMNTGDVGARF 4560
EEVFMECMGLLRPLFLLSGCCQALEISLDQEHIPFGPVVYQTQATRRILMMNTGDVGARF
Sbjct: 4501 EEVFMECMGLLRPLFLLSGCCQALEISLDQEHIPFGPVVYQTQATRRILMMNTGDVGARF 4560
Query: 4561 KWDIKKFEPHFSISPEEGYITSGMEVSFEVTYHPTEVGKESLCKNILCYIQGGSPLSLTL 4620
KWDIKKFEPHFSISPEEGYITSGMEVSFEVTYHPTEVGKESLCKNILCYIQGGSPLSLTL
Sbjct: 4561 KWDIKKFEPHFSISPEEGYITSGMEVSFEVTYHPTEVGKESLCKNILCYIQGGSPLSLTL 4620
Query: 4621 SGVCVGPPAVKEVVNFTCQVRSKHTQTILLSNRTNQTWNLHPIFEGEHWEGPEFITLEAH 4680
SGVCVGPPAVKEVVNFTCQVRSKHTQTILLSNRTNQTWNLHPIFEGEHWEGPEFITLEAH
Sbjct: 4621 SGVCVGPPAVKEVVNFTCQVRSKHTQTILLSNRTNQTWNLHPIFEGEHWEGPEFITLEAH 4680
Query: 4681 QQNKPYEITYRPRTMNLENRKHQGTLFFPLPDGTGWLYALHGTSELPKAVANIYREVPCK 4740
QQNKPYEITYRPRTMNLENRKHQGTLFFPLPDGTGWLYALHGTSELPKAVANIYREVPCK
Sbjct: 4681 QQNKPYEITYRPRTMNLENRKHQGTLFFPLPDGTGWLYALHGTSELPKAVANIYREVPCK 4740
Query: 4741 TPYTELLPITNWLNKPQRFRVIVEILKPEKPDLSITMKGLDYIDVLSGSKKDYKLNFFSH 4800
TPYTELLPITNWLNKPQRFRVIVEILKPEKPDLSITMKGLDYIDVLSGSKKDYKLNFFSH
Sbjct: 4741 TPYTELLPITNWLNKPQRFRVIVEILKPEKPDLSITMKGLDYIDVLSGSKKDYKLNFFSH 4800
Query: 4801 KEGTYAAKVIFRNEVTNEFLYYNVSFRVIPSGIIKTIEMVTPVRQVASASIKLENPLPYS 4860
KEGTYAAKVIFRNEVTNEFLYYNVSFRVIPSGIIKTIEMVTPVRQVASASIKLENPLPYS
Sbjct: 4801 KEGTYAAKVIFRNEVTNEFLYYNVSFRVIPSGIIKTIEMVTPVRQVASASIKLENPLPYS 4860
Query: 4861 VTFSTECRMPDIALPSQFVVPANSEGTFSFEFQPLKAGETFGRLTLHNTDLGYYQYELYL 4920
VTFSTECRMPDIALPSQFVVPANSEGTFSFEFQPLKAGETFGRLTLHNTDLGYYQYELYL
Sbjct: 4861 VTFSTECRMPDIALPSQFVVPANSEGTFSFEFQPLKAGETFGRLTLHNTDLGYYQYELYL 4920
Query: 4921 KATPALPEKPVHFQTVLGSSQIILVKFINYTRQRTEYYCRTDCTDFHAEKLINAAPGGQG 4980
KATPALPEKPVHFQTVLGSSQIILVKFINYTRQRTEYYCRTDCTDFHAEKLINAAPGGQG
Sbjct: 4921 KATPALPEKPVHFQTVLGSSQIILVKFINYTRQRTEYYCRTDCTDFHAEKLINAAPGGQG 4980
Query: 4981 GTEASVEVLFEPSHLGETKGILILSSLAGGEYIIPLFGMALPPKPQGPFSIRAGYSIIIP 5040
GTEASVEVLFEPSHLGETKGILILSSLAGGEYIIPLFGMALPPKPQGPFSIRAGYSIIIP
Sbjct: 4981 GTEASVEVLFEPSHLGETKGILILSSLAGGEYIIPLFGMALPPKPQGPFSIRAGYSIIIP 5040
Query: 5041 FKNVFYHMVTFSIIVDNPAFTIRAGESVRPKKINNITVSFEGNPSGSKTPITTKLTVSCP 5100
FKNVFYHMVTFSIIVDNPAFTIRAGESVRPKKINNITVSFEGNPSGSKTPITTKLTVSCP
Sbjct: 5041 FKNVFYHMVTFSIIVDNPAFTIRAGESVRPKKINNITVSFEGNPSGSKTPITTKLTVSCP 5100
Query: 5101 PGEGSETGVKWVYYLKGITL 5120
PGEGSETGVKWVYYLKGITL
Sbjct: 5101 PGEGSETGVKWVYYLKGITL 5120
>gi|46361983 hydrocephalus inducing isoform b [Homo sapiens]
Length = 1017
Score = 2055 bits (5324), Expect = 0.0
Identities = 1014/1015 (99%), Positives = 1015/1015 (100%)
Query: 1 MTSRRLEESMGAVQMGLVNMFKGFQSKVLPPLSPKVVTEEEVNRMLTPSEFLKEMSLTTE 60
MTSRRLEESMGAVQMGLVNMFKGFQSKVLPPLSPKVVTEEEVNRMLTPSEFLKEMSLTTE
Sbjct: 1 MTSRRLEESMGAVQMGLVNMFKGFQSKVLPPLSPKVVTEEEVNRMLTPSEFLKEMSLTTE 60
Query: 61 QRLAKTRLMCRPQIIELLDMGETTHQKFSGIDLDQALFQPFPSEIIFQNYTPCEVYEVPL 120
QRLAKTRLMCRPQIIELLDMGETTHQKFSGIDLDQALFQPFPSEIIFQNYTPCEVYEVPL
Sbjct: 61 QRLAKTRLMCRPQIIELLDMGETTHQKFSGIDLDQALFQPFPSEIIFQNYTPCEVYEVPL 120
Query: 121 ILRNNDKIPRLVKVVEESSPYFKVISPKDIGHKVAPGVPSIFRILFTPEENKDYAHTLTC 180
ILRNNDKIPRLVKVVEESSPYFKVISPKDIGHKVAPGVPSIFRILFTPEENKDYAHTLTC
Sbjct: 121 ILRNNDKIPRLVKVVEESSPYFKVISPKDIGHKVAPGVPSIFRILFTPEENKDYAHTLTC 180
Query: 181 VTEREKFIVPIKARGARAILDFPDKLNFSTCPVKYSTQKILLVRNIGNKNAVFHIKTCRP 240
VTEREKFIVPIKARGARAILDFPDKLNFSTCPVKYSTQKILLVRNIGNKNAVFHIKTCRP
Sbjct: 181 VTEREKFIVPIKARGARAILDFPDKLNFSTCPVKYSTQKILLVRNIGNKNAVFHIKTCRP 240
Query: 241 FSIEPAIGTLNVGESMQLEVEFEPQSVGDHSGRLIVCYDTGEKVFVSLYGAAIDMNIRLD 300
FSIEPAIGTLNVGESMQLEVEFEPQSVGDHSGRLIVCYDTGEKVFVSLYGAAIDMNIRLD
Sbjct: 241 FSIEPAIGTLNVGESMQLEVEFEPQSVGDHSGRLIVCYDTGEKVFVSLYGAAIDMNIRLD 300
Query: 301 KNSLTIEKTYISLANQRTITIHNRSNIIAHFLWKVFATQQEEDREKYRACDDLIKEEKDE 360
KNSLTIEKTYISLANQRTITIHNRSNIIAHFLWKVFATQQEEDREKYRACDDLIKEEKDE
Sbjct: 301 KNSLTIEKTYISLANQRTITIHNRSNIIAHFLWKVFATQQEEDREKYRACDDLIKEEKDE 360
Query: 361 TDEFFEECITDPLLREHLSVLSRTFANQRRLVQGDSKLFFNNVFTVEPLEGDVWPNSSAE 420
TDEFFEECITDPLLREHLSVLSRTFANQRRLVQGDSKLFFNNVFTVEPLEGDVWPNSSAE
Sbjct: 361 TDEFFEECITDPLLREHLSVLSRTFANQRRLVQGDSKLFFNNVFTVEPLEGDVWPNSSAE 420
Query: 421 ITVYFNPLEAKLYQQTIYCDILGREIRLPLRIKGEGMGPKIHFNFELLDIGKVFTGSAHC 480
ITVYFNPLEAKLYQQTIYCDILGREIRLPLRIKGEGMGPKIHFNFELLDIGKVFTGSAHC
Sbjct: 421 ITVYFNPLEAKLYQQTIYCDILGREIRLPLRIKGEGMGPKIHFNFELLDIGKVFTGSAHC 480
Query: 481 YEAILYNKGSIDALFNMTPPTSALGACFVFSPKEGIIEPSGVQAIQISFSSTILGNFEEE 540
YEAILYNKGSIDALFNMTPPTSALGACFVFSPKEGIIEPSGVQAIQISFSSTILGNFEEE
Sbjct: 481 YEAILYNKGSIDALFNMTPPTSALGACFVFSPKEGIIEPSGVQAIQISFSSTILGNFEEE 540
Query: 541 FLVNVNGSPEPVKLTIRGCVIGPTFHFNVPALHFGDVSFGFPHTLICSLNNTSLIPMTYK 600
FLVNVNGSPEPVKLTIRGCVIGPTFHFNVPALHFGDVSFGFPHTLICSLNNTSLIPMTYK
Sbjct: 541 FLVNVNGSPEPVKLTIRGCVIGPTFHFNVPALHFGDVSFGFPHTLICSLNNTSLIPMTYK 600
Query: 601 LRIPGDGLGHKSISYCEQHVDYKRPSWTKEEISSMKPKEFTISPDCGTIRPQGFAAIRVT 660
LRIPGDGLGHKSISYCEQHVDYKRPSWTKEEISSMKPKEFTISPDCGTIRPQGFAAIRVT
Sbjct: 601 LRIPGDGLGHKSISYCEQHVDYKRPSWTKEEISSMKPKEFTISPDCGTIRPQGFAAIRVT 660
Query: 661 LCSNTVQKYELALVVDVEGIGEEVLALLITARCVVPALHLVNTEVDFGHCFLKYPYEKTL 720
LCSNTVQKYELALVVDVEGIGEEVLALLITARCVVPALHLVNTEVDFGHCFLKYPYEKTL
Sbjct: 661 LCSNTVQKYELALVVDVEGIGEEVLALLITARCVVPALHLVNTEVDFGHCFLKYPYEKTL 720
Query: 721 QLANQDDLPGFYEVQPQVCEEVPTVLFSSPTPSGVISPSSTIHIPLVLETQVTGEHRSTV 780
QLANQDDLPGFYEVQPQVCEEVPTVLFSSPTPSGVISPSSTIHIPLVLETQVTGEHRSTV
Sbjct: 721 QLANQDDLPGFYEVQPQVCEEVPTVLFSSPTPSGVISPSSTIHIPLVLETQVTGEHRSTV 780
Query: 781 YISIFGSQDPPLVCHLKSAGEGPVIYVHPNQVDFGNIYVLKDSSRILNLCNQSFIPAFFQ 840
YISIFGSQDPPLVCHLKSAGEGPVIYVHPNQVDFGNIYVLKDSSRILNLCNQSFIPAFFQ
Sbjct: 781 YISIFGSQDPPLVCHLKSAGEGPVIYVHPNQVDFGNIYVLKDSSRILNLCNQSFIPAFFQ 840
Query: 841 AHMAHKKSLWTIEPNEGMVPPETDVQLALTANLNDTLTFKDCVILDIENSSTYRIPVQAS 900
AHMAHKKSLWTIEPNEGMVPPETDVQLALTANLNDTLTFKDCVILDIENSSTYRIPVQAS
Sbjct: 841 AHMAHKKSLWTIEPNEGMVPPETDVQLALTANLNDTLTFKDCVILDIENSSTYRIPVQAS 900
Query: 901 GTGSTIVSDKPFAPELNLGAHFSLDTHYYHFKLINKGRRIQQLFWMNDSFRPQAKLSKKG 960
GTGSTIVSDKPFAPELNLGAHFSLDTHYYHFKLINKGRRIQQLFWMNDSFRPQAKLSKKG
Sbjct: 901 GTGSTIVSDKPFAPELNLGAHFSLDTHYYHFKLINKGRRIQQLFWMNDSFRPQAKLSKKG 960
Query: 961 RVKKGHAHVQPQPSGSQEPRDPQSPVFHLHPASMELYPGQAIDVILEGYSATPRI 1015
RVKKGHAHVQPQPSGSQEPRDPQSPVFHLHPASMELYPGQAIDVILEGYSATPR+
Sbjct: 961 RVKKGHAHVQPQPSGSQEPRDPQSPVFHLHPASMELYPGQAIDVILEGYSATPRV 1015
Score = 50.4 bits (119), Expect = 4e-05
Identities = 22/69 (31%), Positives = 39/69 (56%)
Query: 1765 IFEIQPISGVLDPGEKSNVQVKFMPKEEKFYSQTLVFQIAQSAQKLTLLARGQGLEPRLE 1824
+F ++P+ G + P + + V F P E K Y QT+ I +L L +G+G+ P++
Sbjct: 403 VFTVEPLEGDVWPNSSAEITVYFNPLEAKLYQQTIYCDILGREIRLPLRIKGEGMGPKIH 462
Query: 1825 FSPSVLDLG 1833
F+ +LD+G
Sbjct: 463 FNFELLDIG 471
Score = 50.1 bits (118), Expect = 6e-05
Identities = 88/425 (20%), Positives = 161/425 (37%), Gaps = 71/425 (16%)
Query: 3889 FSVEPSSGIVPVGKIQKFKVKFSPLDIGDFESNLFCQIPNLPPGEQGPV-LVAKGRSTLP 3947
F P GI+ +Q ++ FS +G+FE + P PV L +G P
Sbjct: 508 FVFSPKEGIIEPSGVQAIQISFSSTILGNFEEEFLVNVNGSPE----PVKLTIRGCVIGP 563
Query: 3948 ICHFDLK-----DSDYISGHQRNPELRGSSGGALDPNTRVIEFTTVGIGGKNLRTFTILN 4002
HF++ D + H L +S L P T + G+G K++
Sbjct: 564 TFHFNVPALHFGDVSFGFPHTLICSLNNTS---LIPMTYKLRIPGDGLGHKSI------- 613
Query: 4003 PTNSTYSFC----------WISEEIESLQNPAAFTCLTEKGFIHPEKKAEIVFQFTPFHL 4052
S+C W EEI S++ P FT + G I P+ A I + T
Sbjct: 614 ------SYCEQHVDYKRPSWTKEEISSMK-PKEFTISPDCGTIRPQGFAAI--RVTLCSN 664
Query: 4053 GITESSWTFLIPEHNI---TVPFLLVGKTTEPLISLNKSHLNFSSLLIGREARETVQIIN 4109
+ + ++ I + L+ + P + L + ++F + +T+Q+ N
Sbjct: 665 TVQKYELALVVDVEGIGEEVLALLITARCVVPALHLVNTEVDFGHCFLKYPYEKTLQLAN 724
Query: 4110 KEE-QGFDFSFQDNSRYSEGFSNSLLVCPM-EGWIPPLSRFPIDIFFTPKQEGDVNFNLI 4167
+++ GF ++ + E L P G I P S I + + G+ +
Sbjct: 725 QDDLPGF---YEVQPQVCEEVPTVLFSSPTPSGVISPSSTIHIPLVLETQVTGEHRSTVY 781
Query: 4168 CNV-EKKVHPVTLNVKAEGYTMNVEIKCKDRTGSITLLTPNQTNIINFYEVELNECVQCE 4226
++ + P+ ++K+ G G + + PNQ + N Y ++ + +
Sbjct: 782 ISIFGSQDPPLVCHLKSAG------------EGPVIYVHPNQVDFGNIYVLKDSSRI--- 826
Query: 4227 FNFINTGKFTFSFQAQLCGSKTLL-----QYLEFSPIDSTVDVGQSVHATLSFQPLKKCV 4281
N N FQA + K+L + + D + + +++ TL+F K CV
Sbjct: 827 LNLCNQSFIPAFFQAHMAHKKSLWTIEPNEGMVPPETDVQLALTANLNDTLTF---KDCV 883
Query: 4282 LTDLE 4286
+ D+E
Sbjct: 884 ILDIE 888
Score = 47.0 bits (110), Expect = 5e-04
Identities = 129/739 (17%), Positives = 250/739 (33%), Gaps = 141/739 (19%)
Query: 3887 QPFSVEPSSGIVPVGKIQKFKVKFSPLDIGDFESNLFCQIPNLPPGEQGPVLVAKGRSTL 3946
+PFS+EP+ G + VG+ + +V+F P +GD L
Sbjct: 239 RPFSIEPAIGTLNVGESMQLEVEFEPQSVGDHSGRLI----------------------- 275
Query: 3947 PICHFDLKDSDYIS--GHQRNPELRGSSGGALDPNTRVIEFTTVGIGGKNLRTFTILNPT 4004
+C +D + ++S G + +R LD N+ IE T + + N RT TI N +
Sbjct: 276 -VC-YDTGEKVFVSLYGAAIDMNIR------LDKNSLTIEKTYISLA--NQRTITIHNRS 325
Query: 4005 NSTYSFCWISEEIESLQNPAAFTCLTEKGFIHPEKKAEIVFQFTPFHLGITESSWTFLIP 4064
N F W + ++ + + + E+K E F
Sbjct: 326 NIIAHFLWKVFATQQEEDREKYRACDD---LIKEEKDETDEFF----------------- 365
Query: 4065 EHNITVPFLLVGKTTEPLISLNKSHLNFSSLLIGREARETVQIINKEEQGFDFSFQDNSR 4124
E IT P L + HL+ S + R ++ + + F
Sbjct: 366 EECITDPLL-------------REHLSVLSRTFANQRR----LVQGDSKLF--------- 399
Query: 4125 YSEGFSNSLLVCPMEGWIPPLSRFPIDIFFTPKQEGDVNFNLICNVEKKVHPVTLNVKAE 4184
F+N V P+EG + P S I ++F P + + C++ + + L +K E
Sbjct: 400 ----FNNVFTVEPLEGDVWPNSSAEITVYFNPLEAKLYQQTIYCDILGREIRLPLRIKGE 455
Query: 4185 GYTMNVEIKCKDRTGSITLLTPNQTNIINFYEVELNECVQCEFNFINTGKFTFSFQAQLC 4244
G + + +++ +V E N G F
Sbjct: 456 GMGPKIHFNFE---------------LLDIGKVFTGSAHCYEAILYNKGSIDALFN-MTP 499
Query: 4245 GSKTLLQYLEFSPIDSTVDVGQSVHATLSFQPLKKCVLTDL--ELIIKISHGP-TFMCNI 4301
+ L FSP + ++ +SF +L + E ++ ++ P I
Sbjct: 500 PTSALGACFVFSPKEGIIEPSGVQAIQISF---SSTILGNFEEEFLVNVNGSPEPVKLTI 556
Query: 4302 SGCAVSPAIHFSFTSYNFG----------TCFIYQAGMPPYKQTLVITNK-------EET 4344
GC + P HF+ + +FG C + + P L I
Sbjct: 557 RGCVIGPTFHFNVPALHFGDVSFGFPHTLICSLNNTSLIPMTYKLRIPGDGLGHKSISYC 616
Query: 4345 PMSIDCLYTNTTHLEVNSR----------VDVVKPGNTLEIPITFYPRESINYQELIPFE 4394
+D + T E++S ++P I +T Y+ + +
Sbjct: 617 EQHVDYKRPSWTKEEISSMKPKEFTISPDCGTIRPQGFAAIRVTLCSNTVQKYELALVVD 676
Query: 4395 INGLSQQTVEIKGKGTKMKILVLDPANRIVKLGAVLPGQVVKRTVSIMNNSLAQLTFNQS 4454
+ G+ ++ + + + + L N V G ++T+ + N L
Sbjct: 677 VEGIGEEVLALL-ITARCVVPALHLVNTEVDFGHCFLKYPYEKTLQLANQD--DLPGFYE 733
Query: 4455 ILFTIPELQEPKVLTLAPFHNITLKPKEVCKLEVIFAPKKRVPPFSEEVFMECMGLLRPL 4514
+ + E + P VL +P + + P + ++ + V++ G P
Sbjct: 734 VQPQVCE-EVPTVLFSSPTPSGVISPSSTIHIPLVLETQV-TGEHRSTVYISIFGSQDPP 791
Query: 4515 FL--LSGCCQALEISLDQEHIPFGPVVYQTQATRRILMMNTGDVGARFKWDIKKFEPHFS 4572
+ L + I + + FG + ++R + + N + A F+ + + ++
Sbjct: 792 LVCHLKSAGEGPVIYVHPNQVDFGNIYVLKDSSRILNLCNQSFIPAFFQAHMAHKKSLWT 851
Query: 4573 ISPEEGYITSGMEVSFEVT 4591
I P EG + +V +T
Sbjct: 852 IEPNEGMVPPETDVQLALT 870
Score = 40.4 bits (93), Expect = 0.046
Identities = 25/103 (24%), Positives = 47/103 (45%), Gaps = 4/103 (3%)
Query: 2919 PAIFQLSCQGIRPELELEPRQLHFDRLLLHRQESRVVLLRNVTLLPVAWRITSLEHLGDD 2978
P + L G P + + P Q+ F + + + SR++ L N + +P ++ + H
Sbjct: 791 PLVCHLKSAGEGPVIYVHPNQVDFGNIYVLKDSSRILNLCNQSFIPAFFQ-AHMAHKKSL 849
Query: 2979 FTVSLMQGTIPPEAEYGLHLYFQPTKPVNIKKAIRLEVLDAEN 3021
+T+ +G +PPE + L L + K + +LD EN
Sbjct: 850 WTIEPNEGMVPPETDVQLALTANLNDTLTFKDCV---ILDIEN 889
Score = 39.3 bits (90), Expect = 0.10
Identities = 20/94 (21%), Positives = 42/94 (44%)
Query: 2876 YFLEPNTMVLKPNEKQILNVWAYPTSVGVFEDSIVCCINDNPEPAIFQLSCQGIRPELEL 2935
+ P +++P+ Q + + T +G FE+ + +N +PEP + I P
Sbjct: 508 FVFSPKEGIIEPSGVQAIQISFSSTILGNFEEEFLVNVNGSPEPVKLTIRGCVIGPTFHF 567
Query: 2936 EPRQLHFDRLLLHRQESRVVLLRNVTLLPVAWRI 2969
LHF + + + L N +L+P+ +++
Sbjct: 568 NVPALHFGDVSFGFPHTLICSLNNTSLIPMTYKL 601
Score = 33.9 bits (76), Expect = 4.3
Identities = 60/287 (20%), Positives = 112/287 (39%), Gaps = 32/287 (11%)
Query: 4286 ELIIKISHGPTFMCNISGCAVSPAIHFSFTS----YNFGTCFIYQAGMPPYKQTLVITNK 4341
++I + G T SG + A+ F S N+ C +Y+ L++ N
Sbjct: 73 QIIELLDMGETTHQKFSGIDLDQALFQPFPSEIIFQNYTPCEVYEV-------PLILRNN 125
Query: 4342 EETPMSIDCLYTNTTHLEVNSRVDV---VKPGNTLEIPITFYPRESINYQELIPFEINGL 4398
++ P + + ++ + +V S D+ V PG I F P E+ +Y + +
Sbjct: 126 DKIPRLVKVVEESSPYFKVISPKDIGHKVAPGVPSIFRILFTPEENKDYAHTLTC-VTER 184
Query: 4399 SQQTVEIKGKGTKMKILVLDPANRIVKLGAVLPGQVVKRTVSIMNNSLAQLTFNQSILFT 4458
+ V IK +G + + D N + P + + + ++ N N++ +F
Sbjct: 185 EKFIVPIKARGARAILDFPDKLNF-----STCPVKYSTQKILLVRN-----IGNKNAVFH 234
Query: 4459 IPELQEPKVLTLAPFHNITLKPKEVCKLEVIFAPKKRVPPFSEEVFMECMGLLRPLFL-L 4517
I + ++ P TL E +LEV F P+ V S + + C +F+ L
Sbjct: 235 IKTCRP---FSIEPAIG-TLNVGESMQLEVEFEPQS-VGDHSGRLIV-CYDTGEKVFVSL 288
Query: 4518 SGCCQALEISLDQEHIPFGPVVYQTQATRRILMMNTGDVGARFKWDI 4564
G + I LD+ + R I + N ++ A F W +
Sbjct: 289 YGAAIDMNIRLDKNSLTIEKTYISLANQRTITIHNRSNIIAHFLWKV 335
Score = 32.7 bits (73), Expect = 9.5
Identities = 26/92 (28%), Positives = 43/92 (46%), Gaps = 10/92 (10%)
Query: 4930 PVHFQTVLGSSQIILVKFINYTRQRTEYYCRTDCTDFHAEKLINAAPGGQGGTEASVEVL 4989
PV + T +I+LV+ N + ++ +T C F E I G+ +EV
Sbjct: 212 PVKYST----QKILLVR--NIGNKNAVFHIKT-CRPFSIEPAIGTLNVGES---MQLEVE 261
Query: 4990 FEPSHLGETKGILILSSLAGGEYIIPLFGMAL 5021
FEP +G+ G LI+ G + + L+G A+
Sbjct: 262 FEPQSVGDHSGRLIVCYDTGEKVFVSLYGAAI 293
>gi|90669228 deleted in lung and esophageal cancer 1 isoform DLEC1-S3
[Homo sapiens]
Length = 1778
Score = 118 bits (296), Expect = 1e-25
Identities = 172/809 (21%), Positives = 307/809 (37%), Gaps = 111/809 (13%)
Query: 94 DQALFQPFPSEIIFQNYTPCEVYEVPLILRNNDKIPRLVKVVEESSPYFKV---ISPKDI 150
D +F P F +Y VYE+ + L+N R ++V+ S+PYF + + P
Sbjct: 368 DTPVFLAKPPIGFFTDYEIGPVYEMVIALQNTTTTSRYLRVLPPSTPYFALGLGMFPGK- 426
Query: 151 GHKVAPGVPSIFRILFTPEENKDYAHTLTCVTE-REKFIVPIKARGARAILDFPDKLNFS 209
G VAPG+ + + F P+ D+ + T+ ++P++AR +L L+
Sbjct: 427 GGMVAPGMTCQYIVQFFPDCLGDFDDFILVETQSAHTLLIPLQARRPPPVLTLSPVLDCG 486
Query: 210 TCPVKYSTQKILLVRNIGNKNAVFHI--KTC-----------------RPFSIEPAIGTL 250
C + + +N+G F I KT PF I P++ L
Sbjct: 487 YCLIGGVKMTRFICKNVGFSVGRFCIMPKTSWPPLSFKAIATVGFVEQPPFGILPSVFEL 546
Query: 251 NVGESMQLEVEFEPQSVGDHSGRLIVCYDTGEKVFVSLYGAAIDMNIRLDKNSLTIEKTY 310
G ++ +EV F P+S+G I+ D + L I I LD ++ EK+
Sbjct: 547 APGHAILVEVLFSPKSLGKAEQTFIIMCDNCQ--IKELVTIGIGQLIALDLIYISGEKSQ 604
Query: 311 ISLANQRTITIHNRSNIIAHFLWKVFATQQEEDREKYRACDDLIKEEKDETDEFFEECIT 370
+T HF+ + E + + A LI + F I
Sbjct: 605 PDPGELTDLTAQ-------HFI------RFEPENLRSTARKQLIIRNATHVELAFYWQIM 651
Query: 371 DPLLREHLSVLSRTFANQRRLVQGDSKLFFNNVFTVEPLEGDVWPNSSAEITVYFNPLEA 430
P L+ + TF+ D + F++ P +G + P++ E + F+P E
Sbjct: 652 KPNLQPLMP--GETFSMDSIKCYPDKE----TAFSIMPRKGVLSPHTDHEFILSFSPHEL 705
Query: 431 KLYQQTIYCDILGREIRLPLRIKGEGMGPKIHFNFELLDIGKVFTGSAHCYEAIL----- 485
+ + + ++ E+ P+ + E +G + +++ + GS ++ +L
Sbjct: 706 RDFHSVL--QMVLEEVPEPVSSEAESLGHSSYSVDDVIVLEIEVKGSVEPFQVLLEPYAL 763
Query: 486 ------YNKGSIDALFNMTPPTSA--------LGACFVF--SPKEGIIEPSGVQAIQISF 529
Y ++ F M + + + C + P G+IEPS V +++F
Sbjct: 764 IIPGENYIGINVKKAFKMWNNSKSPIRYLWGKISDCHIIEVEPGTGVIEPSEVGDFELNF 823
Query: 530 SSTILGNFEEEFLVNVNGSPEPVKLTIRGCVIGPTFHFNVPALHFGDVSFGFPHTLICSL 589
+ + G ++ L + SP PV L I GP NV AL FG + G T +
Sbjct: 824 TGGVPGPTSQDLLCEIEDSPSPVVLHIEAVFKGPALIINVSALQFGLLRLGQKATNSIQI 883
Query: 590 NNTSLIPMTYKLRIPGDGLGHKSISYCEQHVDYKRPSWTKEEISSMKPKEFTISPDCGTI 649
N S +P T++++ + P +E + P F I P G +
Sbjct: 884 RNVSQLPATWRMK--------------------ESPVSLQERPEDVSP--FDIEPSSGQL 921
Query: 650 RPQGFAAIRVTLCSNTVQKYELALVVDVEGIGEEVLALLITARCVVPALHLVNTEVDFGH 709
G + +TL + Q E L ++VE L + A P ++L +++V+ +
Sbjct: 922 HSLGECRVDITLEALHCQHLETVLELEVENGAWSYLP--VYAEVQKPHVYLQSSQVEVRN 979
Query: 710 CFLKYPYEKTLQLANQDDLPGFYEVQPQVCEEVPTVLFSSPTPSGVISPSSTIHIPLVLE 769
+L P + T+ L N LP + + + + + G++ PS + L L
Sbjct: 980 LYLGVPTKTTITLINGTLLPTQFHWGKLLGHQAEFCMVTVSPKHGLLGPSEECQLKLELT 1039
Query: 770 TQVTGEHRSTVYISIFGSQDPPLVCHLKSAGEGPVIYV----------------HPNQ-- 811
E PLV + +G + + HP +
Sbjct: 1040 AHTQEELTHLALPCHVSGMKKPLVLGISGKPQGLQVAITISKESSDCSTEQWPGHPKELR 1099
Query: 812 VDFGNIYVLKDS-SRILNLCNQSFIPAFF 839
+DFG+ L+ +R L L N+S I F
Sbjct: 1100 LDFGSAVPLRTRVTRQLILTNRSPIRTRF 1128
Score = 45.8 bits (107), Expect = 0.001
Identities = 34/146 (23%), Positives = 63/146 (43%), Gaps = 7/146 (4%)
Query: 2878 LEPNTMVLKPNEKQILNVWAYPTSVGVFEDSIVCCINDNPEPAIFQLSCQGIRPELELEP 2937
+EP T V++P+E + G ++C I D+P P + + P L +
Sbjct: 804 VEPGTGVIEPSEVGDFELNFTGGVPGPTSQDLLCEIEDSPSPVVLHIEAVFKGPALIINV 863
Query: 2938 RQLHFDRLLLHRQESRVVLLRNVTLLPVAWRI----TSLEHLGDD---FTVSLMQGTIPP 2990
L F L L ++ + + +RNV+ LP WR+ SL+ +D F + G +
Sbjct: 864 SALQFGLLRLGQKATNSIQIRNVSQLPATWRMKESPVSLQERPEDVSPFDIEPSSGQLHS 923
Query: 2991 EAEYGLHLYFQPTKPVNIKKAIRLEV 3016
E + + + +++ + LEV
Sbjct: 924 LGECRVDITLEALHCQHLETVLELEV 949
Score = 39.3 bits (90), Expect = 0.10
Identities = 33/155 (21%), Positives = 69/155 (44%), Gaps = 9/155 (5%)
Query: 753 SGVISPSSTIHIPLVLETQVTGEHRSTVYISIFGSQDPPLVCHLKSAGEGPVIYVHPNQV 812
+GVI PS L V G + I S P +V H+++ +GP + ++ + +
Sbjct: 808 TGVIEPSEVGDFELNFTGGVPGPTSQDLLCEIEDSPSP-VVLHIEAVFKGPALIINVSAL 866
Query: 813 DFGNIYVLKDSSRILNLCNQSFIPAFFQAHMA--------HKKSLWTIEPNEGMVPPETD 864
FG + + + ++ + + N S +PA ++ + S + IEP+ G + +
Sbjct: 867 QFGLLRLGQKATNSIQIRNVSQLPATWRMKESPVSLQERPEDVSPFDIEPSSGQLHSLGE 926
Query: 865 VQLALTANLNDTLTFKDCVILDIENSSTYRIPVQA 899
++ +T + + L++EN + +PV A
Sbjct: 927 CRVDITLEALHCQHLETVLELEVENGAWSYLPVYA 961
Score = 38.5 bits (88), Expect = 0.17
Identities = 91/407 (22%), Positives = 157/407 (38%), Gaps = 52/407 (12%)
Query: 1271 RPEEKELRKTKASSVISDVRCPFHGEERIYSSQSQVEDQESLQTCEQNEMLSIGI----E 1326
R E + LR T +I +R H E Y Q + + L E M SI E
Sbjct: 620 RFEPENLRSTARKQLI--IRNATHVELAFYW-QIMKPNLQPLMPGETFSMDSIKCYPDKE 676
Query: 1327 EVFDILPLFGVLQPHSSHQISFTFYGHA----NIIAQAKALCEVEEGPTYEITLKGEASL 1382
F I+P GVL PH+ H+ +F H + + Q L EV E + E G +S
Sbjct: 677 TAFSIMPRKGVLSPHTDHEFILSFSPHELRDFHSVLQ-MVLEEVPEPVSSEAESLGHSS- 734
Query: 1383 VNYSFDTK-----DIHYGLQLFDHVTE-REITLTNMGKVGFEFK---VLTDHQSSPDNLL 1433
YS D ++ ++ F + E + + +G K + ++ SP L
Sbjct: 735 --YSVDDVIVLEIEVKGSVEPFQVLLEPYALIIPGENYIGINVKKAFKMWNNSKSPIRYL 792
Query: 1434 PG------VPLILPVSGFISSHQEQVLKVYYLPGVPEVFKRSFQIQIAHLDPENITLSGE 1487
G + + P +G I + ++ + GVP + +I P + L E
Sbjct: 793 WGKISDCHIIEVEPGTGVIEPSEVGDFELNFTGGVPGPTSQDLLCEIED-SPSPVVLHIE 851
Query: 1488 GIFPQICLDLPRNLTANEKYEMFLNQARKNTDKEYNKCEM-----LDHFDIITEEVPED- 1541
+F L + N++A + + L Q N+ + N ++ + + +E PED
Sbjct: 852 AVFKGPALII--NVSALQFGLLRLGQKATNSIQIRNVSQLPATWRMKESPVSLQERPEDV 909
Query: 1542 -----EPAEVSAHLQMEVE-RLIVQSYVLEHQKTTTPDPMDDPCFSHRSRRKLAKIQLPE 1595
EP+ H E + +++ +H +T +++ +S+ A++Q P
Sbjct: 910 SPFDIEPSSGQLHSLGECRVDITLEALHCQHLETVLELEVENGAWSYLP--VYAEVQKPH 967
Query: 1596 YILDFGYI-----ILGEVRTHIIKIINTSHFPVSFHADKRVLHETGF 1637
L + LG I +IN + P FH K + H+ F
Sbjct: 968 VYLQSSQVEVRNLYLGVPTKTTITLINGTLLPTQFHWGKLLGHQAEF 1014
Score = 36.6 bits (83), Expect = 0.66
Identities = 49/227 (21%), Positives = 88/227 (38%), Gaps = 26/227 (11%)
Query: 3889 FSVEPSSGIVPVGKIQKFKVKFSPLDIGDFESNLFCQIPNLPPGEQGPVLVAKGRSTLPI 3948
FS+ P G++ +F + FSP ++ DF S L + E+ P V+ +L
Sbjct: 679 FSIMPRKGVLSPHTDHEFILSFSPHELRDFHSVLQMVL------EEVPEPVSSEAESLGH 732
Query: 3949 CHFDLKDSDYISGHQRNPELRGSSGGALDPNTRVIEFTTVGIGGKNL------RTFTILN 4002
+ + D + E++GS ++P ++E + I G+N + F + N
Sbjct: 733 SSYSVDDVIVL-----EIEVKGS----VEPFQVLLEPYALIIPGENYIGINVKKAFKMWN 783
Query: 4003 PTNSTYSFCWISEEIESLQNPAAFTCLTEKGFIHPEKKAEIVFQFTPFHLGITESSWTFL 4062
+ S + W + + G I P + + FT G T
Sbjct: 784 NSKSPIRYLW-----GKISDCHIIEVEPGTGVIEPSEVGDFELNFTGGVPGPTSQDLLCE 838
Query: 4063 IPEHNITVPFLLVGKTTEPLISLNKSHLNFSSLLIGREARETVQIIN 4109
I + V + P + +N S L F L +G++A ++QI N
Sbjct: 839 IEDSPSPVVLHIEAVFKGPALIINVSALQFGLLRLGQKATNSIQIRN 885
Score = 35.8 bits (81), Expect = 1.1
Identities = 86/480 (17%), Positives = 185/480 (38%), Gaps = 57/480 (11%)
Query: 4135 VCPMEGWIPPLSRFPIDIFFTPKQEGDVNFNLICNVEKKVHPVTLNVKAEGYT------- 4187
+ P +G + P + + F+P + D + L +E+ PV+ ++ G++
Sbjct: 681 IMPRKGVLSPHTDHEFILSFSPHELRDFHSVLQMVLEEVPEPVSSEAESLGHSSYSVDDV 740
Query: 4188 --MNVEIKCKDRTGSI----TLLTPNQTNIINFYEVELNECVQCEFNFINTGKFTFSFQA 4241
+ +E+K GS+ LL P I + +N V+ F N K +
Sbjct: 741 IVLEIEVK-----GSVEPFQVLLEPYALIIPGENYIGIN--VKKAFKMWNNSKSPIRY-- 791
Query: 4242 QLCGSKTLLQYLEFSPIDSTVDVGQSVHATLSFQPLKKCVLTDLELIIKISHGPT-FMCN 4300
L G + +E P ++ + L+F T +L+ +I P+ + +
Sbjct: 792 -LWGKISDCHIIEVEPGTGVIEPSEVGDFELNFTGGVPGP-TSQDLLCEIEDSPSPVVLH 849
Query: 4301 ISGCAVSPAIHFSFTSYNFGTCFIYQAGMPPYK-----QTLVITNKEETPMSIDCLYTNT 4355
I PA+ + ++ FG + Q + Q +E+P+S+ +
Sbjct: 850 IEAVFKGPALIINVSALQFGLLRLGQKATNSIQIRNVSQLPATWRMKESPVSLQERPEDV 909
Query: 4356 THLEVNSRVDVVKPGNTLEIPITFYPRESINYQELIPFEINGLSQQTVEIKGKGTKMKIL 4415
+ ++ + + IT + + ++ E+ + + + + K +
Sbjct: 910 SPFDIEPSSGQLHSLGECRVDITLEALHCQHLETVLELEVENGAWSYLPVYAEVQKPHVY 969
Query: 4416 VLDPANRIVKLGAVLPGQVVKRTVSIMNNSLAQLTFNQSILFTIPELQEPKVLTLAPFHN 4475
+ + L +P K T++++N +L F+ L + E ++T++P H
Sbjct: 970 LQSSQVEVRNLYLGVP---TKTTITLINGTLLPTQFHWGKL--LGHQAEFCMVTVSPKHG 1024
Query: 4476 ITLKPKEVCKLEVIFAPKKRVPPFSEEVFMECMGLLRPLFL-LSGCCQALEISLD----- 4529
+ L P E C+L++ + + G+ +PL L +SG Q L++++
Sbjct: 1025 L-LGPSEECQLKLELTAHTQEELTHLALPCHVSGMKKPLVLGISGKPQGLQVAITISKES 1083
Query: 4530 -------------QEHIPFGPVV-YQTQATRRILMMNTGDVGARFKWDIKKF-EPHFSIS 4574
+ + FG V +T+ TR++++ N + RF + F P S+S
Sbjct: 1084 SDCSTEQWPGHPKELRLDFGSAVPLRTRVTRQLILTNRSPIRTRFSLKFEYFGSPQNSLS 1143
>gi|90669194 deleted in lung and esophageal cancer 1 isoform DLEC1-N1
[Homo sapiens]
Length = 1755
Score = 118 bits (296), Expect = 1e-25
Identities = 172/809 (21%), Positives = 307/809 (37%), Gaps = 111/809 (13%)
Query: 94 DQALFQPFPSEIIFQNYTPCEVYEVPLILRNNDKIPRLVKVVEESSPYFKV---ISPKDI 150
D +F P F +Y VYE+ + L+N R ++V+ S+PYF + + P
Sbjct: 368 DTPVFLAKPPIGFFTDYEIGPVYEMVIALQNTTTTSRYLRVLPPSTPYFALGLGMFPGK- 426
Query: 151 GHKVAPGVPSIFRILFTPEENKDYAHTLTCVTE-REKFIVPIKARGARAILDFPDKLNFS 209
G VAPG+ + + F P+ D+ + T+ ++P++AR +L L+
Sbjct: 427 GGMVAPGMTCQYIVQFFPDCLGDFDDFILVETQSAHTLLIPLQARRPPPVLTLSPVLDCG 486
Query: 210 TCPVKYSTQKILLVRNIGNKNAVFHI--KTC-----------------RPFSIEPAIGTL 250
C + + +N+G F I KT PF I P++ L
Sbjct: 487 YCLIGGVKMTRFICKNVGFSVGRFCIMPKTSWPPLSFKAIATVGFVEQPPFGILPSVFEL 546
Query: 251 NVGESMQLEVEFEPQSVGDHSGRLIVCYDTGEKVFVSLYGAAIDMNIRLDKNSLTIEKTY 310
G ++ +EV F P+S+G I+ D + L I I LD ++ EK+
Sbjct: 547 APGHAILVEVLFSPKSLGKAEQTFIIMCDNCQ--IKELVTIGIGQLIALDLIYISGEKSQ 604
Query: 311 ISLANQRTITIHNRSNIIAHFLWKVFATQQEEDREKYRACDDLIKEEKDETDEFFEECIT 370
+T HF+ + E + + A LI + F I
Sbjct: 605 PDPGELTDLTAQ-------HFI------RFEPENLRSTARKQLIIRNATHVELAFYWQIM 651
Query: 371 DPLLREHLSVLSRTFANQRRLVQGDSKLFFNNVFTVEPLEGDVWPNSSAEITVYFNPLEA 430
P L+ + TF+ D + F++ P +G + P++ E + F+P E
Sbjct: 652 KPNLQPLMP--GETFSMDSIKCYPDKE----TAFSIMPRKGVLSPHTDHEFILSFSPHEL 705
Query: 431 KLYQQTIYCDILGREIRLPLRIKGEGMGPKIHFNFELLDIGKVFTGSAHCYEAIL----- 485
+ + + ++ E+ P+ + E +G + +++ + GS ++ +L
Sbjct: 706 RDFHSVL--QMVLEEVPEPVSSEAESLGHSSYSVDDVIVLEIEVKGSVEPFQVLLEPYAL 763
Query: 486 ------YNKGSIDALFNMTPPTSA--------LGACFVF--SPKEGIIEPSGVQAIQISF 529
Y ++ F M + + + C + P G+IEPS V +++F
Sbjct: 764 IIPGENYIGINVKKAFKMWNNSKSPIRYLWGKISDCHIIEVEPGTGVIEPSEVGDFELNF 823
Query: 530 SSTILGNFEEEFLVNVNGSPEPVKLTIRGCVIGPTFHFNVPALHFGDVSFGFPHTLICSL 589
+ + G ++ L + SP PV L I GP NV AL FG + G T +
Sbjct: 824 TGGVPGPTSQDLLCEIEDSPSPVVLHIEAVFKGPALIINVSALQFGLLRLGQKATNSIQI 883
Query: 590 NNTSLIPMTYKLRIPGDGLGHKSISYCEQHVDYKRPSWTKEEISSMKPKEFTISPDCGTI 649
N S +P T++++ + P +E + P F I P G +
Sbjct: 884 RNVSQLPATWRMK--------------------ESPVSLQERPEDVSP--FDIEPSSGQL 921
Query: 650 RPQGFAAIRVTLCSNTVQKYELALVVDVEGIGEEVLALLITARCVVPALHLVNTEVDFGH 709
G + +TL + Q E L ++VE L + A P ++L +++V+ +
Sbjct: 922 HSLGECRVDITLEALHCQHLETVLELEVENGAWSYLP--VYAEVQKPHVYLQSSQVEVRN 979
Query: 710 CFLKYPYEKTLQLANQDDLPGFYEVQPQVCEEVPTVLFSSPTPSGVISPSSTIHIPLVLE 769
+L P + T+ L N LP + + + + + G++ PS + L L
Sbjct: 980 LYLGVPTKTTITLINGTLLPTQFHWGKLLGHQAEFCMVTVSPKHGLLGPSEECQLKLELT 1039
Query: 770 TQVTGEHRSTVYISIFGSQDPPLVCHLKSAGEGPVIYV----------------HPNQ-- 811
E PLV + +G + + HP +
Sbjct: 1040 AHTQEELTHLALPCHVSGMKKPLVLGISGKPQGLQVAITISKESSDCSTEQWPGHPKELR 1099
Query: 812 VDFGNIYVLKDS-SRILNLCNQSFIPAFF 839
+DFG+ L+ +R L L N+S I F
Sbjct: 1100 LDFGSAVPLRTRVTRQLILTNRSPIRTRF 1128
Score = 45.8 bits (107), Expect = 0.001
Identities = 34/146 (23%), Positives = 63/146 (43%), Gaps = 7/146 (4%)
Query: 2878 LEPNTMVLKPNEKQILNVWAYPTSVGVFEDSIVCCINDNPEPAIFQLSCQGIRPELELEP 2937
+EP T V++P+E + G ++C I D+P P + + P L +
Sbjct: 804 VEPGTGVIEPSEVGDFELNFTGGVPGPTSQDLLCEIEDSPSPVVLHIEAVFKGPALIINV 863
Query: 2938 RQLHFDRLLLHRQESRVVLLRNVTLLPVAWRI----TSLEHLGDD---FTVSLMQGTIPP 2990
L F L L ++ + + +RNV+ LP WR+ SL+ +D F + G +
Sbjct: 864 SALQFGLLRLGQKATNSIQIRNVSQLPATWRMKESPVSLQERPEDVSPFDIEPSSGQLHS 923
Query: 2991 EAEYGLHLYFQPTKPVNIKKAIRLEV 3016
E + + + +++ + LEV
Sbjct: 924 LGECRVDITLEALHCQHLETVLELEV 949
Score = 39.3 bits (90), Expect = 0.10
Identities = 33/155 (21%), Positives = 69/155 (44%), Gaps = 9/155 (5%)
Query: 753 SGVISPSSTIHIPLVLETQVTGEHRSTVYISIFGSQDPPLVCHLKSAGEGPVIYVHPNQV 812
+GVI PS L V G + I S P +V H+++ +GP + ++ + +
Sbjct: 808 TGVIEPSEVGDFELNFTGGVPGPTSQDLLCEIEDSPSP-VVLHIEAVFKGPALIINVSAL 866
Query: 813 DFGNIYVLKDSSRILNLCNQSFIPAFFQAHMA--------HKKSLWTIEPNEGMVPPETD 864
FG + + + ++ + + N S +PA ++ + S + IEP+ G + +
Sbjct: 867 QFGLLRLGQKATNSIQIRNVSQLPATWRMKESPVSLQERPEDVSPFDIEPSSGQLHSLGE 926
Query: 865 VQLALTANLNDTLTFKDCVILDIENSSTYRIPVQA 899
++ +T + + L++EN + +PV A
Sbjct: 927 CRVDITLEALHCQHLETVLELEVENGAWSYLPVYA 961
Score = 38.5 bits (88), Expect = 0.17
Identities = 91/407 (22%), Positives = 157/407 (38%), Gaps = 52/407 (12%)
Query: 1271 RPEEKELRKTKASSVISDVRCPFHGEERIYSSQSQVEDQESLQTCEQNEMLSIGI----E 1326
R E + LR T +I +R H E Y Q + + L E M SI E
Sbjct: 620 RFEPENLRSTARKQLI--IRNATHVELAFYW-QIMKPNLQPLMPGETFSMDSIKCYPDKE 676
Query: 1327 EVFDILPLFGVLQPHSSHQISFTFYGHA----NIIAQAKALCEVEEGPTYEITLKGEASL 1382
F I+P GVL PH+ H+ +F H + + Q L EV E + E G +S
Sbjct: 677 TAFSIMPRKGVLSPHTDHEFILSFSPHELRDFHSVLQ-MVLEEVPEPVSSEAESLGHSS- 734
Query: 1383 VNYSFDTK-----DIHYGLQLFDHVTE-REITLTNMGKVGFEFK---VLTDHQSSPDNLL 1433
YS D ++ ++ F + E + + +G K + ++ SP L
Sbjct: 735 --YSVDDVIVLEIEVKGSVEPFQVLLEPYALIIPGENYIGINVKKAFKMWNNSKSPIRYL 792
Query: 1434 PG------VPLILPVSGFISSHQEQVLKVYYLPGVPEVFKRSFQIQIAHLDPENITLSGE 1487
G + + P +G I + ++ + GVP + +I P + L E
Sbjct: 793 WGKISDCHIIEVEPGTGVIEPSEVGDFELNFTGGVPGPTSQDLLCEIED-SPSPVVLHIE 851
Query: 1488 GIFPQICLDLPRNLTANEKYEMFLNQARKNTDKEYNKCEM-----LDHFDIITEEVPED- 1541
+F L + N++A + + L Q N+ + N ++ + + +E PED
Sbjct: 852 AVFKGPALII--NVSALQFGLLRLGQKATNSIQIRNVSQLPATWRMKESPVSLQERPEDV 909
Query: 1542 -----EPAEVSAHLQMEVE-RLIVQSYVLEHQKTTTPDPMDDPCFSHRSRRKLAKIQLPE 1595
EP+ H E + +++ +H +T +++ +S+ A++Q P
Sbjct: 910 SPFDIEPSSGQLHSLGECRVDITLEALHCQHLETVLELEVENGAWSYLP--VYAEVQKPH 967
Query: 1596 YILDFGYI-----ILGEVRTHIIKIINTSHFPVSFHADKRVLHETGF 1637
L + LG I +IN + P FH K + H+ F
Sbjct: 968 VYLQSSQVEVRNLYLGVPTKTTITLINGTLLPTQFHWGKLLGHQAEF 1014
Score = 36.6 bits (83), Expect = 0.66
Identities = 49/227 (21%), Positives = 88/227 (38%), Gaps = 26/227 (11%)
Query: 3889 FSVEPSSGIVPVGKIQKFKVKFSPLDIGDFESNLFCQIPNLPPGEQGPVLVAKGRSTLPI 3948
FS+ P G++ +F + FSP ++ DF S L + E+ P V+ +L
Sbjct: 679 FSIMPRKGVLSPHTDHEFILSFSPHELRDFHSVLQMVL------EEVPEPVSSEAESLGH 732
Query: 3949 CHFDLKDSDYISGHQRNPELRGSSGGALDPNTRVIEFTTVGIGGKNL------RTFTILN 4002
+ + D + E++GS ++P ++E + I G+N + F + N
Sbjct: 733 SSYSVDDVIVL-----EIEVKGS----VEPFQVLLEPYALIIPGENYIGINVKKAFKMWN 783
Query: 4003 PTNSTYSFCWISEEIESLQNPAAFTCLTEKGFIHPEKKAEIVFQFTPFHLGITESSWTFL 4062
+ S + W + + G I P + + FT G T
Sbjct: 784 NSKSPIRYLW-----GKISDCHIIEVEPGTGVIEPSEVGDFELNFTGGVPGPTSQDLLCE 838
Query: 4063 IPEHNITVPFLLVGKTTEPLISLNKSHLNFSSLLIGREARETVQIIN 4109
I + V + P + +N S L F L +G++A ++QI N
Sbjct: 839 IEDSPSPVVLHIEAVFKGPALIINVSALQFGLLRLGQKATNSIQIRN 885
Score = 35.8 bits (81), Expect = 1.1
Identities = 86/480 (17%), Positives = 185/480 (38%), Gaps = 57/480 (11%)
Query: 4135 VCPMEGWIPPLSRFPIDIFFTPKQEGDVNFNLICNVEKKVHPVTLNVKAEGYT------- 4187
+ P +G + P + + F+P + D + L +E+ PV+ ++ G++
Sbjct: 681 IMPRKGVLSPHTDHEFILSFSPHELRDFHSVLQMVLEEVPEPVSSEAESLGHSSYSVDDV 740
Query: 4188 --MNVEIKCKDRTGSI----TLLTPNQTNIINFYEVELNECVQCEFNFINTGKFTFSFQA 4241
+ +E+K GS+ LL P I + +N V+ F N K +
Sbjct: 741 IVLEIEVK-----GSVEPFQVLLEPYALIIPGENYIGIN--VKKAFKMWNNSKSPIRY-- 791
Query: 4242 QLCGSKTLLQYLEFSPIDSTVDVGQSVHATLSFQPLKKCVLTDLELIIKISHGPT-FMCN 4300
L G + +E P ++ + L+F T +L+ +I P+ + +
Sbjct: 792 -LWGKISDCHIIEVEPGTGVIEPSEVGDFELNFTGGVPGP-TSQDLLCEIEDSPSPVVLH 849
Query: 4301 ISGCAVSPAIHFSFTSYNFGTCFIYQAGMPPYK-----QTLVITNKEETPMSIDCLYTNT 4355
I PA+ + ++ FG + Q + Q +E+P+S+ +
Sbjct: 850 IEAVFKGPALIINVSALQFGLLRLGQKATNSIQIRNVSQLPATWRMKESPVSLQERPEDV 909
Query: 4356 THLEVNSRVDVVKPGNTLEIPITFYPRESINYQELIPFEINGLSQQTVEIKGKGTKMKIL 4415
+ ++ + + IT + + ++ E+ + + + + K +
Sbjct: 910 SPFDIEPSSGQLHSLGECRVDITLEALHCQHLETVLELEVENGAWSYLPVYAEVQKPHVY 969
Query: 4416 VLDPANRIVKLGAVLPGQVVKRTVSIMNNSLAQLTFNQSILFTIPELQEPKVLTLAPFHN 4475
+ + L +P K T++++N +L F+ L + E ++T++P H
Sbjct: 970 LQSSQVEVRNLYLGVP---TKTTITLINGTLLPTQFHWGKL--LGHQAEFCMVTVSPKHG 1024
Query: 4476 ITLKPKEVCKLEVIFAPKKRVPPFSEEVFMECMGLLRPLFL-LSGCCQALEISLD----- 4529
+ L P E C+L++ + + G+ +PL L +SG Q L++++
Sbjct: 1025 L-LGPSEECQLKLELTAHTQEELTHLALPCHVSGMKKPLVLGISGKPQGLQVAITISKES 1083
Query: 4530 -------------QEHIPFGPVV-YQTQATRRILMMNTGDVGARFKWDIKKF-EPHFSIS 4574
+ + FG V +T+ TR++++ N + RF + F P S+S
Sbjct: 1084 SDCSTEQWPGHPKELRLDFGSAVPLRTRVTRQLILTNRSPIRTRFSLKFEYFGSPQNSLS 1143
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 80.1 bits (196), Expect = 5e-14
Identities = 74/327 (22%), Positives = 165/327 (50%), Gaps = 43/327 (13%)
Query: 2272 MKAQEKAKKEQEE-RKHKGALEKEKERLQNMDE---EEYDALTEEEKLTFDRGIQQALRE 2327
++ QEK +EQ+E R+ + +++++E++ +E E+ + + +E+ +++ Q +E
Sbjct: 330 LREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQE 389
Query: 2328 RKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVP 2387
+K R+QE E Q+++L+++ ER +E++++ +V+K ++EE M++ + +
Sbjct: 390 QKMRDQEERMWE-QDERLREKEERMREQEKMWEQVEK-----MREEKKMQEQEKKTRDQE 443
Query: 2388 PLTKVDVKMETIERKISVREQTMSEKEE-LNKKKRNMGDVSMHGLPLVQDQEDSEGDNSK 2446
+ + ++ E+K+ E+TM E+EE + K++ NM + QE+ E +
Sbjct: 444 EKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWE-----------QEEKEWQQQR 492
Query: 2447 DPDKQLAPKFKTYELTLKDVQNILMYWDRKQGV--------QLPPAGMEEAPHEPDDQRQ 2498
P++ K K +E Q + W++++ + Q +E E +DQ
Sbjct: 493 LPEQ----KEKLWEQEKMQEQEEKI-WEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMW 547
Query: 2499 VPLGGRRGRKDRERERL---EKERTEKERLEREKAERERLEKLRALEERSDWEGEGEEDH 2555
+ K R++E+ ++ER EK+ E+EK ++ EK+R E + E + E+
Sbjct: 548 -----EQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEE 602
Query: 2556 EGKKEKDLGVPFLDIQTPDFEGLSWKQ 2582
E +E++ + + + + E W+Q
Sbjct: 603 EMMREQEEKMQEQEEKMQEQEEKMWEQ 629
Score = 73.9 bits (180), Expect = 4e-12
Identities = 78/319 (24%), Positives = 142/319 (44%), Gaps = 27/319 (8%)
Query: 2265 MAQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQA 2324
M + M QEK +EQE+ + EKE + + E+E +EEK+ +
Sbjct: 309 MREQEEKMWRQEKRLREQEKELREQ--EKELREQKELREQEEQMQEQEEKMWEQEEKMRE 366
Query: 2325 LRERKKREQERL---AKEM--QEKKLQQELERQKEEDE--------LKRRVKKGKQ-GPI 2370
E+ R++ERL K+M QE+K++ + ER E+DE ++ + K +Q +
Sbjct: 367 QEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKM 426
Query: 2371 KEEPPMKKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEE-LNKKKRNMGDVSMH 2429
+EE M++ + + + + ++ E+K+ E+TM E+EE + K++ NM +
Sbjct: 427 REEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEK 486
Query: 2430 GLPLVQDQEDSEGDNSKDPDKQLAPKFKTYELTLKDVQNI-----LMYWDRKQGVQLPPA 2484
+ E E ++ ++ K E ++D + + M+ K Q
Sbjct: 487 EWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQM 546
Query: 2485 GMEEAPHEPDDQRQVPLGGRRGRKDRERERL-----EKERTEKERLEREKAERERLEKLR 2539
+E +Q+ R +K +E+E+ EK R E+ EREK RE E +R
Sbjct: 547 WEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMR 606
Query: 2540 ALEERSDWEGEGEEDHEGK 2558
EE+ + E ++ E K
Sbjct: 607 EQEEKMQEQEEKMQEQEEK 625
Score = 73.2 bits (178), Expect = 6e-12
Identities = 72/307 (23%), Positives = 141/307 (45%), Gaps = 26/307 (8%)
Query: 2265 MAQDYAAMKAQEKAKKEQEERK-HKGALEKEKERL---QNMDEEEYDALTEEEKLTFDRG 2320
M + M+ QE+ EQEE++ + L ++KE+L + M E+E +EEK+
Sbjct: 466 MREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEE 525
Query: 2321 I----QQALRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPM 2376
+ ++ R+ K REQE E +EK QE + +E+ ++++ ++ ++ +E M
Sbjct: 526 MWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKM 585
Query: 2377 KKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQD 2436
++ + ++ + + + M E K+ +E+ M E+EE ++ +Q+
Sbjct: 586 REEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEK----------MQE 635
Query: 2437 QEDSEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQ 2496
QE+ + +K + K +E Q ++ K Q EE E +
Sbjct: 636 QEEKMWEQE---EKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKM 692
Query: 2497 RQVPLGGRRGRKDRERERLEKERTEKERLEREKAE--RERLEKLRALEERSDWEGEGEED 2554
+ + D+E+ R E+ E+E+ RE+ E RE+ EK++ EE+ E EE+
Sbjct: 693 EKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQ---EQEEE 749
Query: 2555 HEGKKEK 2561
++EK
Sbjct: 750 MWEQEEK 756
Score = 71.6 bits (174), Expect = 2e-11
Identities = 65/297 (21%), Positives = 148/297 (49%), Gaps = 15/297 (5%)
Query: 2272 MKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKR 2331
M+ QEK ++QEE+ + E+ +ER + M EEE +EEK+ +E K+
Sbjct: 432 MQEQEKKTRDQEEKMQEE--ERIREREKKMREEEETMREQEEKMQKQEENMWE-QEEKEW 488
Query: 2332 EQERLAKEMQEKKLQQELERQKE---EDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPP 2388
+Q+RL ++ ++ Q++++ Q+E E E K R ++ G +E M + + +Q
Sbjct: 489 QQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWG---QEKKMWRQEKMREQEDQ 545
Query: 2389 LTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDP 2448
+ + + KM E+K+ +E+ M +K + +KK + M ++++E + +
Sbjct: 546 MWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMM 605
Query: 2449 DKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRK 2508
+Q K + E +++ + + W++++ +Q M E + +Q + +R +
Sbjct: 606 REQ-EEKMQEQEEKMQEQEEKM--WEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPE 662
Query: 2509 DRERERLEKERTEKERLEREKA---ERERLEKLRALEERSDWEGEGEEDHEGKKEKD 2562
+E+ ++ E+E+++ ++ E+E++EK +E+ W+ E + E +E++
Sbjct: 663 QKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMRERE 719
Score = 68.2 bits (165), Expect = 2e-10
Identities = 69/308 (22%), Positives = 149/308 (48%), Gaps = 43/308 (13%)
Query: 2265 MAQDYAAMKAQEKAKKEQEER--KHKGALEKEKERLQNMDE------------------- 2303
M ++ M+ QE+ +EQEE+ + + + +++E++Q +E
Sbjct: 598 MREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQ 657
Query: 2304 ----EEYDALTEEEKLTFDRGIQQALRERKKREQERLAKEMQE-KKLQQELERQKEEDEL 2358
E+ + L E EK+ +Q+ +E K EQE++ K+ QE +K + E+ +EE+ +
Sbjct: 658 QRLPEQKEKLWEHEKMQEQEKMQE--QEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESM 715
Query: 2359 KRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNK 2418
+ R KK ++ +EE ++ + +Q + + + +M E K+ +E+ M E++ L +
Sbjct: 716 REREKKMRE---EEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPE 772
Query: 2419 KKRNMGD-VSMHGLPLVQDQEDSEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQ 2477
+K + + M + +QE+ D + Q K + E ++ + + + K
Sbjct: 773 QKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQ-EEKMRGQEEKMRGQEEKMWGQEEKM 831
Query: 2478 -GVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRERERLEKERTEKERLEREKAERERLE 2536
G + G EE +++ + + +G++++ RE+ EK R ++E++ RE+ E
Sbjct: 832 WGQEEKMWGQEEKMWGQEEKMEEKM---QGQEEKMREQEEKMRGQEEKM------REQEE 882
Query: 2537 KLRALEER 2544
K+R EE+
Sbjct: 883 KMRGQEEK 890
Score = 65.9 bits (159), Expect = 1e-09
Identities = 61/314 (19%), Positives = 149/314 (47%), Gaps = 31/314 (9%)
Query: 2287 HKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKREQERLAKEMQEKKLQ 2346
++ + E+ + +N + +E L E EK +++ +RK + L ++Q LQ
Sbjct: 214 YRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKEL--KRKLERAKFLLPQVQTNTLQ 271
Query: 2347 QELERQKEE-DELKRRVKKGKQGPIKEEPPMKKSQAA-NKQVPPLTKVDVKMETIERKIS 2404
+E+ RQ+EE E +++++K ++ ++E +++ + +Q + + + ++ E+++
Sbjct: 272 EEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELR 331
Query: 2405 VREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQLAPKFKTYELTLK 2464
+E+ + E++EL +++ M Q+QE+ + + +Q ++ E
Sbjct: 332 EQEKELREQKELREQEEQM-----------QEQEEKMWEQEEKMREQEEKMWRQEE---- 376
Query: 2465 DVQNILMYWDRKQGVQLPPAGMEEAPHE--PDDQRQVPLGGRRGRKDRERERLEKERTEK 2522
W++++ ++ M + D+R R +++ E++EK R EK
Sbjct: 377 ------RLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEK 430
Query: 2523 ERLEREKAERERLEKLRALEERSDWEGEGEEDHEGKKEKDLGVPFLDIQTPDFEGLSWKQ 2582
+ E+EK R++ EK++ E + E + E+ E +E++ + + + E W+Q
Sbjct: 431 KMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQ 490
Query: 2583 ALESDKLPKGEQIL 2596
+LP+ ++ L
Sbjct: 491 ----QRLPEQKEKL 500
Score = 65.5 bits (158), Expect = 1e-09
Identities = 63/313 (20%), Positives = 161/313 (51%), Gaps = 36/313 (11%)
Query: 2273 KAQEKAKKEQEE----RKHKGALEKEKERLQNMDE---EEYDALTEEEKLTFDRGIQQAL 2325
+ +E+ KK +EE R+ + +++++E++Q +E E+ + + E+E+ +++ +
Sbjct: 590 RMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWE 649
Query: 2326 RERKKREQERLAKEMQE----KKLQQELERQKEEDELKRRVKKGKQGPIKE-----EPPM 2376
+E K EQ+RL ++ ++ +K+Q++ + Q++E+++ + K K+ +E + M
Sbjct: 650 QEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKM 709
Query: 2377 KKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEE---LNKKKRNMGDVSMHGLPL 2433
++ ++ ++ + + + M E K+ +E+ M E+EE ++K + M
Sbjct: 710 REEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQR 769
Query: 2434 VQDQEDSEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEP 2493
+ +Q++ ++ K +++ K E ++D + ++ +G + G EE
Sbjct: 770 LPEQKEKLWEHEKMQEQE---KIWEQEEKMRDQE------EKMRGQEEKMRGQEEKMRGQ 820
Query: 2494 DDQ---RQVPLGGRRGRKDRERERL--EKERTEKERLEREKAERERLEKLRALEERSDWE 2548
+++ ++ + G+ + + E++ ++E+ E++ +E+ RE+ EK+R EE+
Sbjct: 821 EEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKM--- 877
Query: 2549 GEGEEDHEGKKEK 2561
E EE G++EK
Sbjct: 878 REQEEKMRGQEEK 890
Score = 63.9 bits (154), Expect = 4e-09
Identities = 77/325 (23%), Positives = 166/325 (51%), Gaps = 31/325 (9%)
Query: 2272 MKAQEKAKKEQEE--RKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERK 2329
M QE+ +EQE+ RK + + +++ERL+ E+E +EEK+ ++ LRE++
Sbjct: 274 MWRQEEELREQEKKIRKQEEKMWRQEERLR---EQEGKMREQEEKMWRQ---EKRLREQE 327
Query: 2330 K--REQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVP 2387
K REQE+ +E +E + Q+E + Q++E+++ + +K ++ +EE ++ + +Q
Sbjct: 328 KELREQEKELREQKELREQEE-QMQEQEEKMWEQEEKMRE---QEEKMWRQEERLWEQEK 383
Query: 2388 PLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGD--VSMHGLPLVQDQEDSEGDNS 2445
+ + + KM E ++ +++ + EKEE +++ M + M +Q+QE D
Sbjct: 384 QMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRD-- 441
Query: 2446 KDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVP----- 2500
++ Q + + E +++ + + ++++ +Q M E + Q+++P
Sbjct: 442 QEEKMQEEERIREREKKMREEEETMR--EQEEKMQKQEENMWEQEEKEWQQQRLPEQKEK 499
Query: 2501 LGGRRGRKDRER---ERLEKERTEKERLEREKAERERLEKLRALEERSDWEGEGEEDHEG 2557
L + +++E E+ EK R ++E +EK + R EK+R E++ WE E + +
Sbjct: 500 LWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEK-KMWRQEKMREQEDQM-WEQEEKMRDQE 557
Query: 2558 KKEKDLGVPFLDIQTPDFEGLSWKQ 2582
+K D ++ +T + E +W Q
Sbjct: 558 QKMWD-QEERMEKKTQEQEKKTWDQ 581
Score = 58.2 bits (139), Expect = 2e-07
Identities = 62/272 (22%), Positives = 127/272 (46%), Gaps = 47/272 (17%)
Query: 2257 REHIYILNMAQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLT 2316
+E ++ Q+ M+ QE+ EQ EK +++ Q +++ +D +EK+
Sbjct: 664 KEKLWEHEKMQEQEKMQEQEEKIWEQ---------EKMEKKTQEQEKKTWD----QEKMR 710
Query: 2317 FDRGIQQALRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPM 2376
+ +++ RE+K RE+E + +E +EK +QE + Q++E+E+ + +K ++E M
Sbjct: 711 EEESMRE--REKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEK----MWEQEEKM 764
Query: 2377 KKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQD 2436
+ Q +Q L + + E + KI +E+ M ++EE K + M G
Sbjct: 765 WEQQRLPEQKEKLWEHEKMQE--QEKIWEQEEKMRDQEE----KMRGQEEKMRG-----Q 813
Query: 2437 QEDSEGDNSK---DPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEP 2493
+E G K +K + K + K W +++ ++ G EE E
Sbjct: 814 EEKMRGQEEKMWGQEEKMWGQEEKMWGQEEK-------MWGQEEKMEEKMQGQEEKMREQ 866
Query: 2494 DDQRQVPLGGRRGRKDRERERLEKERTEKERL 2525
+++ RG++++ RE+ EK R ++E++
Sbjct: 867 EEK-------MRGQEEKMREQEEKMRGQEEKI 891
Score = 57.0 bits (136), Expect = 5e-07
Identities = 69/299 (23%), Positives = 138/299 (46%), Gaps = 54/299 (18%)
Query: 2267 QDYAAMKAQEKAKKEQEERKHKGALEKEKERL-----QNMDEEEY---DALTEEEKLTFD 2318
Q+ + EK++ + ++ K LE+ K L + EE + + L E+EK
Sbjct: 231 QEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRK 290
Query: 2319 RGIQQALRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKK 2378
+ + +E + REQE +E +EK +QE +++E EL+ ++E +++
Sbjct: 291 QEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELR-----------EQEKELRE 339
Query: 2379 SQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEE-LNKKKRNMGDVSMHGLPLVQDQ 2437
+ +Q + + + KM E K+ +E+ M +EE L ++++ M + ++DQ
Sbjct: 340 QKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQK----MRDQ 395
Query: 2438 ED---SEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPD 2494
E+ + + ++ ++++ + K +E K M ++K M+E +
Sbjct: 396 EERMWEQDERLREKEERMREQEKMWEQVEK------MREEKK---------MQEQEKKTR 440
Query: 2495 DQRQVPLGGRRGRKDRERERLEKERTEKERLEREKAERERLEKLRALEERSDWEGEGEE 2553
DQ + K +E ER+ + EK+ E E+ RE+ EK++ EE WE E +E
Sbjct: 441 DQEE---------KMQEEERIRER--EKKMREEEETMREQEEKMQKQEENM-WEQEEKE 487
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 80.1 bits (196), Expect = 5e-14
Identities = 76/308 (24%), Positives = 147/308 (47%), Gaps = 42/308 (13%)
Query: 2275 QEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKK--RE 2332
+E+ E+ E + + LE++ + + + +EE L EE + + ++ RE ++ +E
Sbjct: 1060 EEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQE 1119
Query: 2333 QERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKV 2392
+E+L +E +EK+ +QELERQ E+E V++ ++ ++EEP ++ Q +Q ++
Sbjct: 1120 EEQLLREEREKRRRQELERQYREEE---EVQQEEEQLLREEPEKRRRQELERQYREEEEL 1176
Query: 2393 DVKMETI-----ERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKD 2447
+ E + E++ RE+ E+EEL ++KR Q + D D
Sbjct: 1177 QQEEEQLLREEQEKRRQERERQYREEEELQRQKRK--------------QRYRDEDQRSD 1222
Query: 2448 PDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGR 2507
Q P+ E ++D + + +Q QL + + + + D Q L G +
Sbjct: 1223 LKWQWEPE---KENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQH---LLGEQQE 1276
Query: 2508 KDRERERL-----EKERTEKERLEREKAE-------RERLEKLRALEERSDWEGEGEEDH 2555
+DRE+ER ++ E+E+LERE+ + + + EK EER + E D
Sbjct: 1277 RDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDR 1336
Query: 2556 EGKKEKDL 2563
+ ++E+ L
Sbjct: 1337 KFREEEQL 1344
Score = 74.7 bits (182), Expect = 2e-12
Identities = 75/340 (22%), Positives = 159/340 (46%), Gaps = 35/340 (10%)
Query: 2257 REHIYILNMAQDYAAMKAQEKAKKEQEERKHKGA--LEKEKERLQNMDEEEYDALTEEEK 2314
R+ +L ++ + +EK +++++ER+++ L++E+E+L + E+ E +
Sbjct: 900 RKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQ 959
Query: 2315 LTFDRGIQQALRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEP 2374
D+ +QQ + E E+ ++ +EKK ++E E Q+EE++L R ++ ++ E
Sbjct: 960 YRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQ 1019
Query: 2375 PMKKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEE-----LNKKKRNMGDVSMH 2429
KK + ++ L + K ER+ RE+ ++EE ++ R ++
Sbjct: 1020 YRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQ 1079
Query: 2430 GLPLVQDQEDSEGDNSKDPDKQLAPKFKTY-----ELTLKDVQNILMYWDRKQGVQLPPA 2484
+ Q++ E ++P+K+ + + EL ++ Q + ++++ +L
Sbjct: 1080 YRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQ 1139
Query: 2485 GMEEAPHEPDDQ---RQVPLGGRRGRKDR----------ERERLEKERTEKERLEREKAE 2531
EE + +++ R+ P RR +R E E+L +E EK R ERE+
Sbjct: 1140 YREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQY 1199
Query: 2532 RE--------RLEKLRALEERSD--WEGEGEEDHEGKKEK 2561
RE R ++ R ++RSD W+ E E+++ + K
Sbjct: 1200 REEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNK 1239
Score = 73.2 bits (178), Expect = 6e-12
Identities = 60/305 (19%), Positives = 151/305 (49%), Gaps = 26/305 (8%)
Query: 2272 MKAQEKAKKEQEERKHKGALEKEKERLQNMDEE------EYDALTEEEKLTFDRGIQQAL 2325
++ QE ++ QEE + + L +E++ + +EE E E + +R QQ
Sbjct: 281 LERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLR 340
Query: 2326 RERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQ 2385
RE+++R +++L +E +E++ +Q+L R++EE+ ++++++ +Q ++ E +++ Q ++
Sbjct: 341 REQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQ--LRREQQLRREQQLRRE 398
Query: 2386 VPPLTKVDVKME-TIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDN 2444
+ ++ E + R+ +R + +E+ ++ + L ++QE+
Sbjct: 399 QQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWL 458
Query: 2445 SKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGR 2504
++ + + + + + +D + R++ ++L EE E ++R+ L R
Sbjct: 459 KREEETERHEQERRKQQLKRDQEE----ERRERWLKLE----EEERREQQERREQQL--R 508
Query: 2505 RGRKDRERERLEKERTEKERLEREKAER-------ERLEKLRALEERSDWEGEGEEDHEG 2557
R +++R +RL+++ E+ +R ++E+ ER E+L EE E E E
Sbjct: 509 REQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLK 568
Query: 2558 KKEKD 2562
+++++
Sbjct: 569 REQEE 573
Score = 72.8 bits (177), Expect = 8e-12
Identities = 79/304 (25%), Positives = 147/304 (48%), Gaps = 36/304 (11%)
Query: 2269 YAAMKAQEKAKKEQ----EERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQA 2324
YA QE+ +KEQ EE + E+EK R Q + + EEE+L + +Q
Sbjct: 890 YAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQ----YREEEQLQQEE--EQL 943
Query: 2325 LRER--KKREQERLAKEMQEKKLQQELER-QKEEDELKRRVKKGKQGPIKEEPPMKKSQA 2381
LRE K+R QER + ++KKLQQ+ E+ EE E +RR ++ K+ +EE ++ Q
Sbjct: 944 LREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQL 1003
Query: 2382 ANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSE 2441
++ + + + ER+ +++ E+E+L +++R + ++++ E
Sbjct: 1004 LREE-----REKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQ------ERERQYRE 1052
Query: 2442 GDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPL 2501
+ + ++QL + E + Q + + +++ +Q + EP+ +R+
Sbjct: 1053 EEELQQEEEQLLGE----ERETRRRQELERQYRKEEELQQEEEQL--LREEPEKRRR--- 1103
Query: 2502 GGRRGRKDRERERLEKERTEKERLEREKAERERLEKLRALEERSDWEGEG--EEDHEGKK 2559
R R+ RE E L++E + R EREK R+ LE+ EE E E E+ E ++
Sbjct: 1104 -QERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRR 1162
Query: 2560 EKDL 2563
++L
Sbjct: 1163 RQEL 1166
Score = 72.4 bits (176), Expect = 1e-11
Identities = 71/291 (24%), Positives = 144/291 (49%), Gaps = 41/291 (14%)
Query: 2279 KKEQEERKHKGALEKEKERLQNMDEEE----YDALTEEEKLTFDRGIQQALRERKKREQE 2334
K+E+E +H+ E+ K++L+ EEE + L EEE+ RE+++R ++
Sbjct: 459 KREEETERHE--QERRKQQLKRDQEEERRERWLKLEEEER-----------REQQERREQ 505
Query: 2335 RLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKVDV 2394
+L +E QE++ +Q L+RQ+EE+ L++R++ +Q ++ E ++ Q ++ + +
Sbjct: 506 QLRRE-QEERREQRLKRQEEEERLQQRLRSEQQ--LRREQEERREQLLKREEEKRLEQER 562
Query: 2395 KMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQLAP 2454
+ + ++R+ R + ++EE +++R L ++QE+ K + +
Sbjct: 563 REQRLKREQEERRDQLLKREEERRQQR-----------LKREQEERLEQRLKREEVERLE 611
Query: 2455 KFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRERER 2514
+ + E LK + +R+Q + L EE + + Q +R +++ E ER
Sbjct: 612 QEERREQRLKREE---PEEERRQQL-LKSEEQEERRQQQLRREQQERREQRLKREEEEER 667
Query: 2515 LE---KERTEKERLEREKAERER---LEKLRALEERSDWEGEGEEDHEGKK 2559
LE K E+ER E+E AE E+ E++++ + W+ E E D K
Sbjct: 668 LEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSK 718
Score = 70.9 bits (172), Expect = 3e-11
Identities = 63/300 (21%), Positives = 147/300 (49%), Gaps = 34/300 (11%)
Query: 2273 KAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDR-GIQQALR---ER 2328
K +EK ++E+ +R+ + L++E+E+L+ ++ +E +EE+ R +Q LR E
Sbjct: 255 KEEEKLQEEEPQRQRE--LQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEE 312
Query: 2329 KKREQERLAKEMQEKKLQQELERQ----KEEDELKRRVKKGKQGPIKEEPPMKKSQAANK 2384
++REQ+ +E QE++ QQE R+ +E++E + + + +Q + E +++ Q +
Sbjct: 313 ERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEER 372
Query: 2385 QVPPLTKVDV--KMETIERKISV-REQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSE 2441
+ L + + + + R+ + REQ + +++L ++++ + + ++ +++ E
Sbjct: 373 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEE 432
Query: 2442 GDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPL 2501
K ++ + K + +D W +++ EE ++R+ L
Sbjct: 433 RHEQKHEQERREQRLKREQEERRD-------WLKRE---------EETERHEQERRKQQL 476
Query: 2502 GGRRGRKDRERERLEKERTEKERLEREKAERERLEKLRALEERSDWEGEGEEDHEGKKEK 2561
++D+E ER E+ +E RE+ ER + R EER + + +E+ E +++
Sbjct: 477 -----KRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQR 531
Score = 68.6 bits (166), Expect = 2e-10
Identities = 64/291 (21%), Positives = 144/291 (49%), Gaps = 26/291 (8%)
Query: 2279 KKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKRE--QERL 2336
++E+E RK + L KE+E+LQ + + L EEE+ Q+ RER++ E Q+RL
Sbjct: 241 EEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRL 300
Query: 2337 AKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKVDVKM 2396
+E Q ++ Q+E ER+++++E + + ++ +Q + E +++ Q ++ + + +
Sbjct: 301 RREQQLRRKQEE-ERREQQEERREQQERREQQEERREQQLRREQEERRE--QQLRREQEE 357
Query: 2397 ETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQLAPKF 2456
E E+++ ++ +++L ++++ + + ++ ++ + ++QL
Sbjct: 358 ERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQL---- 413
Query: 2457 KTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKD-----RE 2511
E L+ Q + + ++ E HE + + Q + R+D E
Sbjct: 414 -RREQQLRREQQLRREQEEER---------HEQKHEQERREQRLKREQEERRDWLKREEE 463
Query: 2512 RERLEKERTEKERLEREKAERERLEKLRALEERSDWEGEGEEDHEGKKEKD 2562
ER E+ER K++L+R++ E ER E+ LEE E + + + ++E++
Sbjct: 464 TERHEQER-RKQQLKRDQ-EEERRERWLKLEEEERREQQERREQQLRREQE 512
Score = 66.6 bits (161), Expect = 6e-10
Identities = 71/316 (22%), Positives = 147/316 (46%), Gaps = 47/316 (14%)
Query: 2273 KAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKRE 2332
+ +++ K+EQEER+ + +E+ R Q + E+ + L + K R + L + ++RE
Sbjct: 562 RREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLK----REEVERLEQEERRE 617
Query: 2333 QERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKV 2392
Q +E +E++ QQ L+ +++E+ ++++++ +Q + E +K+ + + L +
Sbjct: 618 QRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQE--RREQRLKREEEEERLEQRLKR- 674
Query: 2393 DVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKD----- 2447
E + REQ ++E+E+ ++R + P Q Q +SE D +
Sbjct: 675 -------EHEEERREQELAEEEQEQARERIKSRI-----PKWQWQLESEADARQSKVYSR 722
Query: 2448 PDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGME-----------EAPHEPDDQ 2496
P KQ + + + + + + W ++ E E E Q
Sbjct: 723 PRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQ 782
Query: 2497 R---QVPLGGRRGRKDRERERLEKER----TEKERLEREKAERERLEKLRALEE-----R 2544
R + PL +R R+ R ER ++E+ E+E+ +R + RER ++L+ LEE R
Sbjct: 783 RLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQR 842
Query: 2545 SDWEGEGEEDHEGKKE 2560
+ + +E+ +G +E
Sbjct: 843 RERAQQLQEEEDGLQE 858
Score = 66.2 bits (160), Expect = 8e-10
Identities = 70/329 (21%), Positives = 148/329 (44%), Gaps = 33/329 (10%)
Query: 2273 KAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALT--EEEKLTFDRGIQQALRERKK 2330
+ +++ K+++EE + + L E++ + +E L EE++L +R Q+ RE+++
Sbjct: 514 RREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEE 573
Query: 2331 REQERLAKEMQEKKLQQELERQKE---EDELKRRVKKGKQGPIKEEPPMKKSQAANKQVP 2387
R + L +E E++ QQ L+R++E E LKR + + + E +K+ + ++
Sbjct: 574 RRDQLLKRE--EERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQ 631
Query: 2388 PLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKD 2447
L K + + E ++++ REQ E+ E K+ + L ++E E + +++
Sbjct: 632 QLLKSEEQEERRQQQLR-REQ--QERREQRLKREEEEERLEQRLKREHEEERREQELAEE 688
Query: 2448 PDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGR 2507
+Q + K+ + W + + + P + + QR R
Sbjct: 689 EQEQARERIKS--------RIPKWQWQLESEADARQSKVYSRPRKQEGQR---------R 731
Query: 2508 KDRERERLEKERTEKERLEREKAERERLEKLRALEERSD--WEGEGEEDHEGKKEKDLGV 2565
+ + E+ + +E + E E+A R++ E+ E+R D W+ + EE E +++
Sbjct: 732 RQEQEEKRRRRESELQWQEEERAHRQQQEE----EQRRDFTWQWQAEEKSERGRQRLSAR 787
Query: 2566 PFLDIQTPDFEGLSWKQALESDKLPKGEQ 2594
P L Q +Q E LP+ E+
Sbjct: 788 PPLREQRERQLRAEERQQREQRFLPEEEE 816
Score = 66.2 bits (160), Expect = 8e-10
Identities = 72/308 (23%), Positives = 156/308 (50%), Gaps = 30/308 (9%)
Query: 2267 QDYAAMKAQEKAKKEQEE--RKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQA 2324
Q + Q++ ++E++ R+ + L++ +E+ + E + L EE +L QQ
Sbjct: 1602 QQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQL 1661
Query: 2325 L--RERKKREQERLAKEMQEKKLQ-QELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQA 2381
R+RK RE+E+L +E +E++L+ QE +R+ E+E + R ++ ++ ++EE +++ +
Sbjct: 1662 RHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQEL 1721
Query: 2382 ANK-----QVPPLTKVD-VKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQ 2435
K Q+ T+ + ++ + RKI EQ E+EE +++ L Q
Sbjct: 1722 ERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQ 1781
Query: 2436 DQEDSEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDD 2495
++E+ + S++ D+ KF+ E ++ ++ QL P + ++
Sbjct: 1782 EREEQQ-LRSQESDR----KFREEEQLRQE----------REEQQLRPQQRDGKYRWEEE 1826
Query: 2496 QRQVPLGGRRGRKDRERE-RLEKERTEKERLEREKAERERLEKLRALEERSDWEGEGEED 2554
Q Q+ +R R++R+R+ R E++ +E+ RE+ E + E+ + +ER E + E+
Sbjct: 1827 QLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQER---ERKLREE 1883
Query: 2555 HEGKKEKD 2562
H +++K+
Sbjct: 1884 HIRRQQKE 1891
Score = 64.7 bits (156), Expect = 2e-09
Identities = 63/292 (21%), Positives = 137/292 (46%), Gaps = 33/292 (11%)
Query: 2275 QEKAKKEQEERKHKGALEKEKERLQNMD---EEEYDALTEEEKLTFDRGIQQALRERKKR 2331
++ ++E E + KG EK+++R + D +EE + + + + ++ E +R
Sbjct: 208 EQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQR 267
Query: 2332 EQERLAKEMQEKKLQ-QELERQKEEDELK-RRVKKGKQGPIKEEPPMKKSQAANKQVPPL 2389
++E +E Q +KL+ QEL R+++E+E + +R+++ +Q K+E ++ Q ++
Sbjct: 268 QRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERRE---- 323
Query: 2390 TKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPD 2449
+ E E++ REQ + ++E ++++ L Q++E E ++ +
Sbjct: 324 -----QQERREQQEERREQQLRREQEERREQQ---------LRREQEEERREQQLRREQE 369
Query: 2450 KQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKD 2509
++ + E L+ Q + ++ QL E +R+ L RR ++
Sbjct: 370 EERREQQLRREQQLRREQQLRREQQLRREQQL--------RREQQLRREQQL--RREQQL 419
Query: 2510 RERERLEKERTEKERLEREKAERERLEKLRALEERSDWEGEGEEDHEGKKEK 2561
R ++L +E+ E+ ++ + ER R EER DW EE ++E+
Sbjct: 420 RREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQER 471
Score = 63.9 bits (154), Expect = 4e-09
Identities = 76/310 (24%), Positives = 146/310 (47%), Gaps = 45/310 (14%)
Query: 2272 MKAQEKAKKEQEERKHKGALEKEKERL---QNMDEEEYDALTEEEKLTFDRGIQQALRER 2328
+ QE+ +K +EE + E+E++ L Q + +E + EEE+L +R QQ R+
Sbjct: 1423 LSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQE 1482
Query: 2329 KKR----EQERLAKEMQEKKL-QQELERQK-------EEDELKRRVKKGKQGPIKEEPPM 2376
+ R E+++L ++ +++K +QEL Q+ EE +L R+ ++ K ++EE +
Sbjct: 1483 RDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKF--LQEEQQL 1540
Query: 2377 KKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEE--LNKKKRNMGDVSMHGLPLV 2434
++ + + + + +RK EQ E+EE L++++R+
Sbjct: 1541 RRQERGQQ----------RRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRR 1590
Query: 2435 QDQ-----EDSEGDNSKDPDKQLAP----KFKTYELTLKDVQNILMYWDRKQGVQLPPAG 2485
Q+Q ED + ++ +QL KF+ E L++ + ++ + L
Sbjct: 1591 QEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFL---- 1646
Query: 2486 MEEAPHEPDDQRQVPLGGRRGRKDRERERLEKERTEKE--RLEREKAERERLEKLRALEE 2543
EE P +R+ L R RK RE E+L +E E++ R ER++ RE ++LR E
Sbjct: 1647 -EEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQER 1705
Query: 2544 RSDWEGEGEE 2553
+ E ++
Sbjct: 1706 ERKFLQEEQQ 1715
Score = 63.2 bits (152), Expect = 7e-09
Identities = 70/349 (20%), Positives = 150/349 (42%), Gaps = 58/349 (16%)
Query: 2263 LNMAQDYAAMKAQEKAKKEQEERKHKG-------------------ALEKEKERLQNMDE 2303
L Q+ + QE+ +++QE R+ + E+E+ER +
Sbjct: 306 LRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLR 365
Query: 2304 EEYDALTEEEKLTFDRGI---------------------------QQALRERKKREQERL 2336
E + E++L ++ + QQ RE++ R +++L
Sbjct: 366 REQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQL 425
Query: 2337 AKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKVDVKM 2396
+E +E++ +Q+ E+++ E LKR ++ + +EE + Q KQ K D +
Sbjct: 426 RREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQ---QLKRDQEE 482
Query: 2397 ETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQL--AP 2454
E ER + + E+ E++E +++ L + +E+ ++QL
Sbjct: 483 ERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQ 542
Query: 2455 KFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRERER 2514
+ + +L ++ + L R+Q ++ + + +++R+ ++ K + ER
Sbjct: 543 EERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERR-----QQRLKREQEER 597
Query: 2515 LEK--ERTEKERLEREKAERERLEKLRALEERSDWEGEGEEDHEGKKEK 2561
LE+ +R E ERLE+E+ +RL++ EER + EE E ++++
Sbjct: 598 LEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQ 646
Score = 60.5 bits (145), Expect = 4e-08
Identities = 67/293 (22%), Positives = 136/293 (46%), Gaps = 18/293 (6%)
Query: 2273 KAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKRE 2332
+ QE+ ++ E R + E + R Q E+E + EE+ ++Q R+R+ E
Sbjct: 113 RRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEE 172
Query: 2333 QERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKV 2392
R +E QE++ ER+ EE++L + +G EE P + Q +++ L +
Sbjct: 173 LWRQRQEWQERE-----ERRAEEEQL-----QSCKGHETEEFP-DEEQLRRRELLELRRK 221
Query: 2393 DVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQL 2452
+ E +++ +++ E+EE +KR V +Q++E ++ ++QL
Sbjct: 222 G-REEKQQQRRERQDRVFQEEEEKEWRKRE--TVLRKEEEKLQEEEPQRQRELQEEEEQL 278
Query: 2453 APKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRER 2512
K + EL ++ Q R + Q EE E ++R+ R +++R
Sbjct: 279 R-KLERQELR-RERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERRE 336
Query: 2513 ERLEKERTEK--ERLEREKAERERLEKLRALEERSDWEGEGEEDHEGKKEKDL 2563
++L +E+ E+ ++L RE+ E R ++LR +E E + + + ++E+ L
Sbjct: 337 QQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQL 389
Score = 60.5 bits (145), Expect = 4e-08
Identities = 74/307 (24%), Positives = 140/307 (45%), Gaps = 29/307 (9%)
Query: 2272 MKAQEKAKKEQEERKHKGALEKEKERLQNMD-EEEYDALTEEEKLTFDRGIQQALRERKK 2330
++A+E+ ++EQ + EKE+ R Q + E+E L EEE+L Q+ R ++
Sbjct: 798 LRAEERQQREQRFLPEEE--EKEQRRRQRREREKELQFLEEEEQL------QRRERAQQL 849
Query: 2331 REQERLAKEMQEKKLQQELERQKE-----EDELKRRVKKGKQGPIKEEPPMKKSQAANKQ 2385
+E+E +E QE++ QE R ++ E+E KRR P +E K+ Q ++
Sbjct: 850 QEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEE 909
Query: 2386 VPPLTKVD---VKMETIERKISVREQTMSEKEEL---NKKKRNMGDVSMH---GLPLVQD 2436
L + + + + ER+ EQ E+E+L ++KR + L Q
Sbjct: 910 EEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQK 969
Query: 2437 QEDSEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQ 2496
+E G+ + +Q K E L+ + L+ +R++ + E +
Sbjct: 970 EEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQE 1029
Query: 2497 RQVPLGGRRGRKDRERERL-EKERTEKERLEREKAERERLEKLRALEERSDWEGEGEEDH 2555
+ L R++RE+ RL E+ER +E E ++ E + L + R R + E + ++
Sbjct: 1030 EEQLL-----REEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEE 1084
Query: 2556 EGKKEKD 2562
E ++E++
Sbjct: 1085 ELQQEEE 1091
Score = 58.9 bits (141), Expect = 1e-07
Identities = 72/317 (22%), Positives = 149/317 (47%), Gaps = 41/317 (12%)
Query: 2273 KAQEKAKKEQEERKHKGALEKEKERLQNMDE---EEYDALTEEEKLTFDRGIQ-QALRER 2328
+A+ + +K QEE++ +EK R Q D EE L E E+ R + + RE
Sbjct: 1306 EAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREE 1365
Query: 2329 KKREQERLAKEMQEKKLQQELERQ----KEEDELK-----RRVKKGKQGPIKEEPPMKKS 2379
+ R QE+ K ++E++ + ER+ KEE +L+ +++++ + +EE
Sbjct: 1366 ELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSR 1425
Query: 2380 QAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQED 2439
Q +++ + V+ + ERK EQ + ++E ++K R L+Q++E+
Sbjct: 1426 QERDRKFRE-EEQQVRRQERERKFLEEEQQL--RQERHRKFREEEQ-------LLQEREE 1475
Query: 2440 SEGDNSK------DPDKQLA-----PKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEE 2488
+ + + ++QL KF+ EL ++ + + ++ QL +
Sbjct: 1476 QQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFL----EEEQQLHRQQRQR 1531
Query: 2489 APHEPDDQRQVPLGGRRGRKDRERERLEKERTEKERLEREKAERERLEKLRALEE---RS 2545
+ + Q + G++ R+DR+R+ E+E+ +ER E++ + +ER K R E+ R
Sbjct: 1532 KFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQ 1591
Query: 2546 DWEGEGEEDHEGKKEKD 2562
+ E + ED + + ++
Sbjct: 1592 EQERKFMEDEQQLRRQE 1608
Score = 58.5 bits (140), Expect = 2e-07
Identities = 66/328 (20%), Positives = 143/328 (43%), Gaps = 39/328 (11%)
Query: 2266 AQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQAL 2325
+++ + Q+ +++QE R+ + E+E+ERL+ + E++ E++L + Q+
Sbjct: 636 SEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEE--QEQA 693
Query: 2326 RERKK-----------REQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEP 2374
RER K E + ++ + +QE +R+++E E KRR ++ + +EE
Sbjct: 694 RERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRR-RRESELQWQEEE 752
Query: 2375 PMKKSQAANKQVPPLT---KVDVKMETIERKISVREQTMSEKE-ELNKKKRNMGDVSMHG 2430
+ Q +Q T + + K E +++S R ++E +L ++R +
Sbjct: 753 RAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQR--- 809
Query: 2431 LPLVQDQEDSEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAP 2490
+ ++E+ E + +++ +F E L+ + + + G+Q
Sbjct: 810 --FLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQE 867
Query: 2491 HEPDDQRQVPLGGRRGRK--------------DRERERLEKERTEKERLEREKAERERLE 2536
D + + L R R+ +E++ L++E E +R EREK R+ E
Sbjct: 868 QRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQE 927
Query: 2537 KLRALEERSDWEGEG--EEDHEGKKEKD 2562
+ EE+ E E E+ E ++ ++
Sbjct: 928 RQYREEEQLQQEEEQLLREEREKRRRQE 955
Score = 58.5 bits (140), Expect = 2e-07
Identities = 72/304 (23%), Positives = 130/304 (42%), Gaps = 51/304 (16%)
Query: 2267 QDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEE---EYDALTEEEKLTFDRGIQQ 2323
+D ++ +E+ + ++ER K E+ + R Q +++ + D EE+ G +Q
Sbjct: 1623 EDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQ 1682
Query: 2324 ALR-----------ERKKREQERLAKEMQEKK--LQQELERQKEEDELKRRVKKGKQGPI 2370
LR E++ R QER K +QE++ +QELER+ E+E R ++ +Q +
Sbjct: 1683 QLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLR--QETEQEQL 1740
Query: 2371 KEEPPMKKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHG 2430
+ + +K + P + ++ + +RK EQ E+EE
Sbjct: 1741 RRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREE--------------- 1785
Query: 2431 LPLVQDQEDSEGDNSKDPDKQLAPKFKTYELTLKDVQNILMY-WDRKQGVQLPPAGMEEA 2489
Q E D ++QL + + E L+ Q Y W+ +Q +QL
Sbjct: 1786 ----QQLRSQESDRKFREEEQL--RQEREEQQLRPQQRDGKYRWEEEQ-LQL-------- 1830
Query: 2490 PHEPDDQRQVPLGGRRGRKDRERERLEKERTEKERLEREKAERERLEKLRALEERSDWEG 2549
E +QR R+ R + + EK R E++ L +E+ ++ R E+ R L E
Sbjct: 1831 --EEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQ 1888
Query: 2550 EGEE 2553
+ EE
Sbjct: 1889 QKEE 1892
Score = 56.6 bits (135), Expect = 6e-07
Identities = 70/317 (22%), Positives = 145/317 (45%), Gaps = 47/317 (14%)
Query: 2272 MKAQEKAKKEQEERKHKGALEK---EKERLQNMDEEEYDALTEEEKLTF-DRGIQQAL-R 2326
++ QE+ +K +E+ E+ E+E+ + + + L EE++L +RG Q+ R
Sbjct: 1494 LRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDR 1553
Query: 2327 ERKKREQERLAKEMQEKKL-QQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQ 2385
+RK RE+E+L +E +E++L +QE +R+ +E K R ++ ++ +++E +++ + +
Sbjct: 1554 DRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQ- 1612
Query: 2386 VPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDS----- 2440
++ E +RK EQ + E+EE ++ + P ++ QE
Sbjct: 1613 --------LRQER-DRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRH 1663
Query: 2441 --------------EGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGM 2486
EG+ + ++ KF+ E L+ + + +Q QL +
Sbjct: 1664 DRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQ--QLRRQEL 1721
Query: 2487 EEAPHEPDDQRQVPLGGRRGRKDRERERLEKERTEKERLEREKAERERLEKLRALEERSD 2546
E E + RQ + E+E+L ++ ++ LE E+ ER E+ +ER
Sbjct: 1722 ERKFREEEQLRQ----------ETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDR 1771
Query: 2547 WEGEGEEDHEGKKEKDL 2563
E E+ + ++E+ L
Sbjct: 1772 KFREEEQLRQEREEQQL 1788
Score = 53.9 bits (128), Expect = 4e-06
Identities = 68/299 (22%), Positives = 126/299 (42%), Gaps = 44/299 (14%)
Query: 2275 QEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQAL------RER 2328
Q K Q E + + A+ K + + E++ L E+ DR QQ L ++
Sbjct: 1219 QRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQL--EDSQLRDRQSQQDLQHLLGEQQE 1276
Query: 2329 KKREQERLAKEMQEKKLQQELERQKEED-ELKRRVKKGKQGPIKEEPPMKKSQAANKQVP 2387
+ REQER + +++ +E + ++EE E KRR +K +EE + + + K+
Sbjct: 1277 RDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKS-----QEEKQLLREEREEKR-- 1329
Query: 2388 PLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKD 2447
+ + +RK EQ + E+EE PL + + D + +
Sbjct: 1330 -------RRQETDRKFREEEQLLQEREE---------------QPLRRQERDRKFREEEL 1367
Query: 2448 PDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGR 2507
++ KF E L+ + + +Q QL E+ + D++ + R
Sbjct: 1368 RHQEQGRKFLEEEQRLRRQERERKFLKEEQ--QLRCQEREQQLRQDRDRKFREEEQQLSR 1425
Query: 2508 KDRERERLEKE----RTEKERLEREKAERERLEKLRALEERSDWEGEGEEDHEGKKEKD 2562
++R+R+ E+E R E+ER E+ ++ R E+ R E E EE ++E+D
Sbjct: 1426 QERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERD 1484
Score = 52.8 bits (125), Expect = 9e-06
Identities = 42/195 (21%), Positives = 94/195 (48%), Gaps = 39/195 (20%)
Query: 2267 QDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALR 2326
Q+ ++ QE +K +EE + L +E E+ Q +E Y + EEE+L +R QQ R
Sbjct: 1711 QEEQQLRRQELERKFREEEQ----LRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRR 1766
Query: 2327 E---RKKREQERLAKEMQEKKL-----------QQELERQKEEDELK------------- 2359
+ RK RE+E+L +E +E++L +++L +++EE +L+
Sbjct: 1767 QERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEE 1826
Query: 2360 --------RRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKVDVKMETIERKISVREQTMS 2411
+R+++ + + E + + ++ L + + + ER+ +RE+ +
Sbjct: 1827 QLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIR 1886
Query: 2412 EKEELNKKKRNMGDV 2426
+++ ++ R +G++
Sbjct: 1887 RQQKEEQRHRQVGEI 1901
Score = 51.2 bits (121), Expect = 3e-05
Identities = 75/355 (21%), Positives = 156/355 (43%), Gaps = 52/355 (14%)
Query: 2257 REHIYILNMAQDYAAMKAQEKAKKEQEERKHKGALEK--EKERLQNMDEEEYDALTEEEK 2314
RE +L ++ + + K +EE +H+ K E+E+ E E L EE++
Sbjct: 1339 REEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQ 1398
Query: 2315 LTFDRGIQQALRERKKR---EQERLAKEMQEKKLQ--------QELERQKEEDELKRRVK 2363
L QQ ++R ++ E+++L+++ +++K + QE ER+ E+E + R +
Sbjct: 1399 LRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQE 1458
Query: 2364 KGKQGPIKEEPPM---KKSQAANKQV--PPLTKVDVKMETIERKISVREQT--------- 2409
+ ++ +EE + ++ Q ++Q + + ++ ER REQ
Sbjct: 1459 RHRK--FREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERK 1516
Query: 2410 -MSEKEELNKKKRNMGDVSMHGLPLVQD---QEDSEGDNSKDPDKQLAPKFKTYELTLKD 2465
+ E+++L++++R + Q+ Q + D ++QL + + +L+ ++
Sbjct: 1517 FLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQE 1576
Query: 2466 VQNILMYWDRK-QGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRERERLEKERTEKER 2524
++K + + ME+ + Q L R RK RE E+L +ER E+++
Sbjct: 1577 RDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQER-EEQQ 1635
Query: 2525 LEREKAERERLE-----------------KLRALEERSDWEGEGEEDHEGKKEKD 2562
L R++ +R+ LE + R E EGEE ++E+D
Sbjct: 1636 LHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERD 1690
Score = 50.1 bits (118), Expect = 6e-05
Identities = 64/319 (20%), Positives = 143/319 (44%), Gaps = 55/319 (17%)
Query: 2267 QDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALR 2326
++ + ++ ++E E+R+ + LE++ + + +EE L EE+
Sbjct: 1143 EEEVQQEEEQLLREEPEKRRRQ-ELERQYREEEELQQEEEQLLREEQ------------- 1188
Query: 2327 ERKKREQERLAKEMQEKKLQQELERQKEED---ELKRRVKKGKQGPIKEEPPMKKSQAAN 2383
E++++E+ER +E +E + Q+ +R ++ED +LK + + K+ +++ K + N
Sbjct: 1189 EKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGR-EN 1247
Query: 2384 KQVPPLTKVDVK----METIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQED 2439
+Q L ++ + ++ + +++ E+E ++R+ L + +E
Sbjct: 1248 EQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEA 1307
Query: 2440 SEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRK--QGVQLPPAGMEEAPHEPDDQR 2497
D +KQL + + + ++ DRK + QL ++E +P ++
Sbjct: 1308 KRRDRKSQEEKQLLREEREEKRRRQET-------DRKFREEEQL----LQEREEQPLRRQ 1356
Query: 2498 QVPLGGRRGRKDRERERLEKER-----TEKERLEREKAERERL---------EKLRALEE 2543
+ R RK RE E +E+ E++RL R++ ER+ L E+ + L +
Sbjct: 1357 E------RDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQ 1410
Query: 2544 RSDWEGEGEEDHEGKKEKD 2562
D + EE ++E+D
Sbjct: 1411 DRDRKFREEEQQLSRQERD 1429
Score = 45.4 bits (106), Expect = 0.001
Identities = 34/127 (26%), Positives = 69/127 (54%), Gaps = 17/127 (13%)
Query: 2263 LNMAQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMD------EEEYDALTEEEKLT 2316
L ++ +++QE +K +EE + + E+++ R Q D EE+ +E++L
Sbjct: 1779 LRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLR 1838
Query: 2317 FDRGIQQ------ALRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQ--- 2367
+R Q A +E+ +RE++ L +E +E+K +QE ER+ E+ ++R+ K+ ++
Sbjct: 1839 QERDRQYRAEEQFATQEKSRREEQELWQE-EEQKRRQERERKLREEHIRRQQKEEQRHRQ 1897
Query: 2368 -GPIKEE 2373
G IK +
Sbjct: 1898 VGEIKSQ 1904
Score = 39.7 bits (91), Expect = 0.078
Identities = 22/102 (21%), Positives = 58/102 (56%), Gaps = 9/102 (8%)
Query: 2273 KAQEKAKKEQEERKHKGA-----LEKEKERLQNMDEEEYDA----LTEEEKLTFDRGIQQ 2323
+ +++ + +Q + K++ LE++++RL+ + +Y A T+E+ ++ + Q
Sbjct: 1807 REEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQ 1866
Query: 2324 ALRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKG 2365
+++++E+ER +E ++ Q+E +R ++ E+K + KG
Sbjct: 1867 EEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQEGKG 1908
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 75.1 bits (183), Expect = 2e-12
Identities = 68/284 (23%), Positives = 143/284 (50%), Gaps = 46/284 (16%)
Query: 2273 KAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKRE 2332
K +E+ K++++E K EK +E+ + + E+E +EEK+ I++ E K++E
Sbjct: 404 KIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIRE---EEKRQE 460
Query: 2333 QERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKV 2392
QE + ++ ++ + Q+E+ RQKE+ + +++K +EE ++ + + Q + +
Sbjct: 461 QEEMWRQEEKIREQEEIWRQKEKMHEQEKIRK------QEEKVWRQEEKMHDQEEKIREQ 514
Query: 2393 DVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQL 2452
+ KM E KI +E+ + E+EE +++ M +Q+QE+ G+ + +Q
Sbjct: 515 EEKMWRQEEKIREQEEKIREQEEKIREQEEM----------MQEQEEKMGEQEEKMQEQ- 563
Query: 2453 APKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRER 2512
K + E +++ + + ++K+ ++ EE E ++ K RE+
Sbjct: 564 -EKMRRQEEKIREQEEKIR--EQKEKIR----EQEEKIWEQEE------------KIREQ 604
Query: 2513 ERLEKERTEK------ERLEREKAERERLEKLRALEERSDWEGE 2550
E + +E+ EK + E+E+ +E+ EK+R EE+ WE E
Sbjct: 605 EEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKM-WEQE 647
Score = 70.9 bits (172), Expect = 3e-11
Identities = 68/295 (23%), Positives = 147/295 (49%), Gaps = 51/295 (17%)
Query: 2272 MKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKR 2331
M QEK ++++E+R+ + + ++++R E+E +EEK+ R ++ +RE++K+
Sbjct: 386 MHEQEKIREQEEKRQEEEKIREQEKR----QEQEAKMWRQEEKI---REQEEKIREQEKK 438
Query: 2332 EQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPI-KEEPPMKKSQAANKQVPPLT 2390
+ K +++K+++E +RQ++E+ ++ K +Q I +++ M + + KQ +
Sbjct: 439 MWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVW 498
Query: 2391 KVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDK 2450
+ + KM E KI +E+ M +EE +++QE+
Sbjct: 499 RQEEKMHDQEEKIREQEEKMWRQEEK-----------------IREQEE----------- 530
Query: 2451 QLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDR 2510
K + E +++ + ++ + K G Q EE E + R+ R ++++
Sbjct: 531 ----KIREQEEKIREQEEMMQEQEEKMGEQ------EEKMQEQEKMRRQEEKIRE-QEEK 579
Query: 2511 ERERLEKERTEKERL-EREKAERERLEKLRALEERSDWEGEGE--EDHEGKKEKD 2562
RE+ EK R ++E++ E+E+ RE+ E ++ EE+ WE E + E E +E++
Sbjct: 580 IREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKM-WEQEEKMCEQEEKMQEQE 633
Score = 63.5 bits (153), Expect = 5e-09
Identities = 61/320 (19%), Positives = 156/320 (48%), Gaps = 21/320 (6%)
Query: 2263 LNMAQDYAAMKAQEKAKK------EQEE--RKHKGALEKEKERLQNMDE---EEYDALTE 2311
LN Q+ + +EK ++ EQEE R+ + + +++E+++ +E E+ + +
Sbjct: 294 LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRR 353
Query: 2312 EEKLTFDRGIQQALRERKKREQERLAKEMQEKKLQQE-LERQKEEDELKRRVKKGKQGPI 2370
+E++ +++ + E E+E +E++EK +QE + Q+E+ + + ++++ ++
Sbjct: 354 QEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQE 413
Query: 2371 KEEPPMKKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHG 2430
+E ++ + +Q + + + KM E KI +E+ E++ +++ + +
Sbjct: 414 QEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIRE 473
Query: 2431 LPLVQDQEDSEGDNS---KDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGME 2487
+ Q++ + K +K + K ++ K + W +++ ++ +
Sbjct: 474 QEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIR 533
Query: 2488 EAPHEPDDQRQV--PLGGRRGRKDRERERLEKERTEKERL-EREKAERERLEKLRALEER 2544
E + +Q ++ + G ++ + + EK R ++E++ E+E+ RE+ EK+R EE+
Sbjct: 534 EQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEK 593
Query: 2545 SDWEGEGE--EDHEGKKEKD 2562
WE E + E E +E++
Sbjct: 594 I-WEQEEKIREQEEMMQEQE 612
Score = 60.8 bits (146), Expect = 3e-08
Identities = 57/283 (20%), Positives = 133/283 (46%), Gaps = 24/283 (8%)
Query: 2283 EERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKREQERLAKEMQE 2342
EE K K A +EK +L ++ E +E K +R +++ + E + L KE+Q
Sbjct: 217 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 276
Query: 2343 KKLQQELERQKEEDELKRRVKKGKQGPI--KEEPPMKKSQAANKQVPPLTKVDVKMETIE 2400
+ +L+ Q EE+EL R+ + ++ + +EE + + +Q + + + K+ E
Sbjct: 277 --VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQE 334
Query: 2401 RKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQLAPKFKTYE 2460
K+ +E+ M EKEE +++ M +++ + ++ + K + E
Sbjct: 335 EKMRRQEEMMWEKEEKMRRQEEM-----------MWEKEEKMRRLEEMMWEKEEKIRELE 383
Query: 2461 LTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRERERLEKERT 2520
+ + + I +++Q EE ++RQ ++++ RE+ EK R
Sbjct: 384 EKMHEQEKIREQEEKRQ---------EEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE 434
Query: 2521 EKERLEREKAERERLEKLRALEERSDWEGEGEEDHEGKKEKDL 2563
+++++ R++ + EK+R E+R + E ++ + ++++++
Sbjct: 435 QEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEI 477
Score = 54.3 bits (129), Expect = 3e-06
Identities = 44/165 (26%), Positives = 83/165 (50%), Gaps = 25/165 (15%)
Query: 2272 MKAQEKAKKEQE-----ERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALR 2326
M QEK +K++E E K EK +E+ + M +E +EEK+ +
Sbjct: 484 MHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIRE--------Q 535
Query: 2327 ERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIK-----------EEPP 2375
E K REQE + +E +EK +QE E+ +E+++++R+ +K ++ K EE
Sbjct: 536 EEKIREQEEMMQEQEEKMGEQE-EKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKI 594
Query: 2376 MKKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKK 2420
++ + +Q + + + KM E K+ +E+ M E+EE +++
Sbjct: 595 WEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQ 639
Score = 49.7 bits (117), Expect = 8e-05
Identities = 35/164 (21%), Positives = 95/164 (57%), Gaps = 10/164 (6%)
Query: 2272 MKAQEKAKKEQEER--KHKGALEKEKERLQNMDE---EEYDALTEEEKLTFDRGIQQALR 2326
M QE+ +EQEE+ + + + +++E+++ +E E+ + + E+E+ ++ + +
Sbjct: 504 MHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQ 563
Query: 2327 ERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQV 2386
E+ +R++E++ +E +EK +Q+ + +++E+++ + +K ++ +EE ++ + +Q
Sbjct: 564 EKMRRQEEKI-REQEEKIREQKEKIREQEEKIWEQEEKIRE---QEEMMQEQEEKMWEQE 619
Query: 2387 PPLTKVDVKMETIERKISVREQTMSEKE-ELNKKKRNMGDVSMH 2429
+ + + KM+ E K+ +E+ M E+E L +++ M + H
Sbjct: 620 EKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEH 663
Score = 48.5 bits (114), Expect = 2e-04
Identities = 25/98 (25%), Positives = 59/98 (60%), Gaps = 5/98 (5%)
Query: 2267 QDYAAMKAQEKAKKEQEE--RKHKGALEKEKERLQNMDE---EEYDALTEEEKLTFDRGI 2321
Q+ M+ QE+ +EQEE R+ K + +++E++ +E E+ + + E+E+ +++
Sbjct: 561 QEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEE 620
Query: 2322 QQALRERKKREQERLAKEMQEKKLQQELERQKEEDELK 2359
+ +E K +EQE + +EK +QE+ +++E++++
Sbjct: 621 KMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 658
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 73.9 bits (180), Expect = 4e-12
Identities = 86/367 (23%), Positives = 160/367 (43%), Gaps = 38/367 (10%)
Query: 2265 MAQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQA 2324
M + M+ QEK +EQE+ + EKE + + E+E +EEK+ +
Sbjct: 271 MREQEEKMRRQEKRLREQEKELREQ--EKELREQKKLREQEEQMQEQEEKMWEQEEKMRE 328
Query: 2325 LRERKKREQERL---AKEM--QEKKLQQELERQKEEDELKRRVKKGKQGPIK---EEPPM 2376
E+ R++ERL K+M QE+K++ + ER E+DE R ++ + K +E M
Sbjct: 329 QEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKM 388
Query: 2377 KKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEEL----------------NKKK 2420
++ + ++ + + + M E K+ +E+ M E+EE +K
Sbjct: 389 QEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKM 448
Query: 2421 RNMGDVSMHGLPLVQDQEDSEGDNSK--DPDKQLAPKFKTYELTLKDVQNILMYWDRKQG 2478
+ + ++DQE+ G K +K + + +E K WD+++
Sbjct: 449 QEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEER 508
Query: 2479 VQLPPAGMEEAPHEPDDQR---QVPLGGRRGRKDRERERL-----EKERTEKERLEREKA 2530
+ + E +Q+ Q R +K +E+E+ EK R E+ EREK
Sbjct: 509 MWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKK 568
Query: 2531 ERERLEKLRALEERSDWEGEGEEDHEGKK-EKDLGVPFLDIQTPDFEGLSWKQALESDKL 2589
RE E +R EE+ + E + E K E++ + + + + E W+Q E DK+
Sbjct: 569 MREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE-EEDKM 627
Query: 2590 PKGEQIL 2596
+ E+++
Sbjct: 628 QEQEEMM 634
Score = 68.2 bits (165), Expect = 2e-10
Identities = 75/304 (24%), Positives = 156/304 (51%), Gaps = 32/304 (10%)
Query: 2272 MKAQEKAKKEQEE--RKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERK 2329
M QE+ +EQE+ RK + + +++ERL+ E+E +EEK+ R ++ LRE++
Sbjct: 236 MWRQEEELREQEKKIRKQEEKMWRQEERLR---EQEGKMREQEEKM---RRQEKRLREQE 289
Query: 2330 K--REQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVP 2387
K REQE+ +E Q+K +QE + Q++E+++ + +K ++ +EE ++ + +Q
Sbjct: 290 KELREQEKELRE-QKKLREQEEQMQEQEEKMWEQEEKMRE---QEEKMWRQEERLWEQEK 345
Query: 2388 PLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKD 2447
+ + + KM E ++ +++ + EKEE +++ M + Q+++ E + ++
Sbjct: 346 QMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWE---------QEEKMQEEERIRE 396
Query: 2448 PDKQLAPKFKTY----ELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGG 2503
+K++ + +T E K +N+ +++ Q P E+ + Q Q
Sbjct: 397 REKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIW 456
Query: 2504 RRGRKDRERERL---EKERTEKERL-EREKAERERLEKLRALEERS-DWEGEGEEDHEGK 2558
+ K R++E + EK+ +E++ E+E E+ EK+R E++ D E E E
Sbjct: 457 EQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERL 516
Query: 2559 KEKD 2562
+EK+
Sbjct: 517 REKE 520
Score = 67.0 bits (162), Expect = 5e-10
Identities = 75/318 (23%), Positives = 145/318 (45%), Gaps = 37/318 (11%)
Query: 2265 MAQDYAAMKAQEKAKKEQEERK-HKGALEKEKERL---QNMDEEEYDALTEEEKLTFDRG 2320
M + M+ QE+ EQEE++ + L ++KE+L + M E+E +EEK+
Sbjct: 408 MREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEE 467
Query: 2321 I----QQALRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPM 2376
+ ++ R+ K REQE E +EK QE + +E+ + + ++ ++E+
Sbjct: 468 MWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDER-----LREKEER 522
Query: 2377 KKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQD 2436
+ Q Q + + K + E+K +E+ M E+E + ++++ M + ++++
Sbjct: 523 MREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEE----EMMRE 578
Query: 2437 QEDSEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQ 2496
QE+ + +K + K +E K + W++++ M E E Q
Sbjct: 579 QEEKMQEQE---EKMREQEEKMWEQEEKMQEQEEKMWEQEEK-------MWEQEEEDKMQ 628
Query: 2497 RQVPLGGRRGRKDRERERLEKERTEKERLEREKA--ERERL----EKLRALEERSDWE-- 2548
Q + + K +E+E E+ EK R + EK + E++ EK+R EE+ +
Sbjct: 629 EQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEE 688
Query: 2549 --GEGEEDHEGKKEKDLG 2564
E EE G++EK G
Sbjct: 689 KMREQEEKMRGQEEKMWG 706
Score = 66.2 bits (160), Expect = 8e-10
Identities = 61/293 (20%), Positives = 146/293 (49%), Gaps = 33/293 (11%)
Query: 2267 QDYAAMKAQEKAKKEQEE-RKHKGALEKEKERLQNMDEEEYDA----LTEEEKLTFDRGI 2321
+D M QEK QE+ R+ + + +++E++++ +++ +D ++E+L R
Sbjct: 463 RDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERL---REK 519
Query: 2322 QQALRERKK--REQERLAKEM----QEKKLQQELERQKEEDELKRRVKKGKQGPI----K 2371
++ +RE+KK +++E++ +E QEKK + E+ +EE+ ++ R KK ++ +
Sbjct: 520 EERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQ 579
Query: 2372 EEPPMKKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGL 2431
EE ++ + +Q + + + KM+ E K+ +E+ M E+EE +K
Sbjct: 580 EEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDK------------- 626
Query: 2432 PLVQDQEDSEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPH 2491
+Q+QE+ + + +Q ++ E + + + ++ QG + EE
Sbjct: 627 --MQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQ 684
Query: 2492 EPDDQRQVPLGGRRGRKDRERERLEKERTEKERLEREKAERERLEKLRALEER 2544
+++ + RG++++ + EK ++E++ ++ RE+ E++R +E+
Sbjct: 685 GQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEK 737
Score = 65.9 bits (159), Expect = 1e-09
Identities = 66/302 (21%), Positives = 143/302 (47%), Gaps = 31/302 (10%)
Query: 2272 MKAQEKAKKEQEER----KHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRE 2327
M+ QE+ EQEE+ + EK+ R + M E+E +EEK+ E
Sbjct: 448 MQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEE 507
Query: 2328 RKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVP 2387
R + ERL ++ + + Q+++ +Q+E+ +++ ++ ++ +E M++ + ++
Sbjct: 508 RMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREK 567
Query: 2388 PLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKD 2447
+ + + M E K+ +E+ M E+EE ++ +Q+QE+ + +
Sbjct: 568 KMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEK----------MQEQEEKMWEQEE- 616
Query: 2448 PDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGM---EEAPHEPDDQRQVPLGGR 2504
K E K + M W++++ +Q M EE E +++ +
Sbjct: 617 -------KMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKM 669
Query: 2505 RGRKDRERERLEKERTEKERL-EREKAERERLEKLRALEERSDWEGE----GEEDHEGKK 2559
+G++++ RE+ EK + ++E++ E+E+ R + EK+ EE+ W E G+E+ K+
Sbjct: 670 QGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKM-WGQEEKMWGQEEMREKE 728
Query: 2560 EK 2561
E+
Sbjct: 729 ER 730
Score = 60.5 bits (145), Expect = 4e-08
Identities = 45/197 (22%), Positives = 99/197 (50%), Gaps = 21/197 (10%)
Query: 2265 MAQDYAAMKAQEKAKKEQEER--KHKGALEKEKERLQNMDE-----EEYDALTEEEKLTF 2317
M + M+ QE+ +EQEE+ + + +++++E++ +E EE D + E+E++ +
Sbjct: 576 MREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMW 635
Query: 2318 DRGIQQALRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKK--GKQGPIKEEPP 2375
++ + +E K EQE +E +EK +QE + Q +E++++ + +K G++ ++E+
Sbjct: 636 EQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEE 695
Query: 2376 MKKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQ 2435
+ Q + KM E K+ +E+ M +EE+ +K+ + D +
Sbjct: 696 KMRGQ------------EEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLP 743
Query: 2436 DQEDSEGDNSKDPDKQL 2452
+ E+ + P K L
Sbjct: 744 EHEERCSEPCLPPSKVL 760
Score = 54.7 bits (130), Expect = 2e-06
Identities = 68/295 (23%), Positives = 135/295 (45%), Gaps = 52/295 (17%)
Query: 2283 EERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRG------IQ-QALRERKKREQER 2335
EE K K A +EK RL ++ E +E K +R +Q L+E R++E
Sbjct: 183 EELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEE 242
Query: 2336 LAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKVDVK 2395
L + QEKK++++ E+ ++E R ++G ++E+ + Q + +
Sbjct: 243 LRE--QEKKIRKQEEKMWRQEERLRE----QEGKMREQEEKMRRQ------------EKR 284
Query: 2396 METIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQLAPK 2455
+ E+++ +E+ + E+++L +++ M Q+QE+ + + +Q K
Sbjct: 285 LREQEKELREQEKELREQKKLREQEEQM-----------QEQEEKMWEQEEKMREQ-EEK 332
Query: 2456 FKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRERERL 2515
E L + + + ++K Q EE E D++ + + + RE+E++
Sbjct: 333 MWRQEERLWEQEKQMREQEQKMRDQ------EERMWEQDERLR-----EKEERMREQEKM 381
Query: 2516 ---EKERTEKERL-EREKAERERLEKLRALEERSDWEGEGEEDHEGKKEKDLGVP 2566
E++ E+ER+ EREK RE E +R EE+ + E + E K+ + +P
Sbjct: 382 WEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLP 436
Score = 51.2 bits (121), Expect = 3e-05
Identities = 52/237 (21%), Positives = 107/237 (45%), Gaps = 15/237 (6%)
Query: 2265 MAQDYAAMKAQEKAKKEQE-----ERKHKGALEKEKERLQNMDEEEYDALTEEEKL-TFD 2318
M ++ + ++K ++E+E E K + EK +E+ + M E+E +EEK+ +
Sbjct: 556 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 615
Query: 2319 RGIQQALRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKK 2378
+ + E K +EQE + E +EK +QE + ++E++++ + +K ++ +EE +
Sbjct: 616 EKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMRE---QEEKMQGQ 672
Query: 2379 SQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQE 2438
+ +Q + + KM E K+ +E+ M +EE K + M G ++++E
Sbjct: 673 EEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEE----KMWGQEEKMWGQEEMREKE 728
Query: 2439 DSEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDD 2495
+ D + ++L + +L V+ PAG E P D
Sbjct: 729 ERIRDQKEKMQERLPEHEERCSEPCLPPSKVLCNMSHTGSVE--PAGGEAGEGSPQD 783
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 73.9 bits (180), Expect = 4e-12
Identities = 83/366 (22%), Positives = 156/366 (42%), Gaps = 67/366 (18%)
Query: 2265 MAQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQA 2324
+A + A ++A+EKA ++ ER+ E E + M EEE A E +++ +
Sbjct: 288 IADERARIEAEEKAAAQERERR-------EAEERERMREEEKRAAEERQRIKEEEKRAAE 340
Query: 2325 LRERKKREQERLAKEMQ-----EKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKS 2379
R+R K E++R A+E Q EK+ +E +R + E+E K +V++ K+ EE K
Sbjct: 341 ERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEE----KK 396
Query: 2380 QAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQED 2439
A + + +K E +E+KI E + +N+KK + L +++
Sbjct: 397 HA-------MQETKIKGEKVEQKI--------EGKWVNEKKAQEDKLQTAVLKKQGEEKG 441
Query: 2440 SEGDNSKDPDKQLAPKFKTYELTLKDV-------QNILMYWDRKQGVQ------------ 2480
++ ++ ++ P FK E+ + + + + + DRK+G
Sbjct: 442 TKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTH 501
Query: 2481 ---------LPPAGM--------EEAPHEPDDQRQVPLGGRRGRKDRERERLEKERTEKE 2523
P G E AP +R L RRG + E K++ ++
Sbjct: 502 KLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEA 561
Query: 2524 RLEREKAERERLEKLRALEERSDWEGEGEEDHEGKKEKDLGVPFLDIQTPDFEGLSWKQA 2583
LE E+ +++R E+ + LEE + E D + ++E++ +I+ E +Q
Sbjct: 562 ALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQK 621
Query: 2584 LESDKL 2589
+ D L
Sbjct: 622 MPEDGL 627
Score = 60.1 bits (144), Expect = 6e-08
Identities = 72/312 (23%), Positives = 139/312 (44%), Gaps = 33/312 (10%)
Query: 2275 QEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKREQE 2334
QE+ +++QEE ++ + QN +E +A T + + A ER R +E
Sbjct: 47 QERLRQKQEEESLGQVTDQVEVNAQNSVPDE-EAKTTTTNTQVEGDDEAAFLERLARREE 105
Query: 2335 RLAKEMQEKKLQQELERQKEED------ELKRRVKKGKQGPIKEEPPMKKSQAANKQ--- 2385
R ++K+LQ+ LERQKE D L ++ + + E K+ ++ ++Q
Sbjct: 106 R-----RQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERY 160
Query: 2386 ----VPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSE 2441
+TK K + + + + +E E+EE K KR G + + + ++ +++ +E
Sbjct: 161 EIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKR--GSIGENQVEVMVEEKTTE 218
Query: 2442 GDNS----KDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQR 2497
+ Q++ + E + + + + ++ + A E A E +++
Sbjct: 219 SQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERE 278
Query: 2498 QVPLGGRRGRKDRERERLEKER----TEKERLEREKAERERLEKLRALEER---SDWEGE 2550
++ + D ER R+E E E+ER E E+ ER R E+ RA EER + E
Sbjct: 279 RIKAEQDKKIAD-ERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKR 337
Query: 2551 GEEDHEGKKEKD 2562
E+ + KE++
Sbjct: 338 AAEERQRIKEEE 349
Score = 58.2 bits (139), Expect = 2e-07
Identities = 75/358 (20%), Positives = 149/358 (41%), Gaps = 75/358 (20%)
Query: 2268 DYAAMKAQEKAKKEQEERKHKGALEKEKE---------------RLQNMDEEEYDALTEE 2312
D AA + ++E+ +++ + ALE++KE R+QN D E + +E
Sbjct: 92 DEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQN-DTAENETTEKE 150
Query: 2313 EKLTFDRGIQQALRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKE 2372
EK ++ +ER + E+ + +K ++ E K+ED+ K +E
Sbjct: 151 EK-------SESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEE---------EE 194
Query: 2373 EPPMKKSQAANKQVPPLTK---VDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMH 2429
E K+ QV + + + + ET+ + + + E ++ ++++ ++S H
Sbjct: 195 EEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHH 254
Query: 2430 GLPLVQDQEDSEGDNSK-----------DPDKQLAPKFKTYELTLKDVQNILMYWDRKQG 2478
+D+E +E + ++ + DK++A + E K
Sbjct: 255 EKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEK-------------- 300
Query: 2479 VQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRERERLEKERTEKERL------EREKAER 2532
A E E +++ ++ +R ++R+R + E++R +ER +R ER
Sbjct: 301 ----AAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEER 356
Query: 2533 ERL--EKLRALEERSDWEGEGEED---HEGKKEKDLGVPFLDIQTPDFEGLSWKQALE 2585
+R+ E+ RA EER E EE E K+ K L +Q +G +Q +E
Sbjct: 357 QRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIE 414
Score = 50.8 bits (120), Expect = 3e-05
Identities = 62/298 (20%), Positives = 122/298 (40%), Gaps = 53/298 (17%)
Query: 2261 YILNMAQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRG 2320
Y N +D K ++K K+E+EE K K E + ++E+ ++ E ++ G
Sbjct: 172 YQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNG 231
Query: 2321 IQQALRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQ 2380
Q E K+E+ER E+ + +K E+E K R + + EE K++
Sbjct: 232 --QISSEEPKQEEER------EQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAE 283
Query: 2381 AANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDS 2440
K +++ E K + +E+ E EE + + + +
Sbjct: 284 QDKKIADERARIEA-----EEKAAAQERERREAEERERMREE------------EKRAAE 326
Query: 2441 EGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVP 2500
E K+ +K+ A + +Q ++ EE ++++++
Sbjct: 327 ERQRIKEEEKRAA--------------------EERQRIK------EEEKRAAEERQRIK 360
Query: 2501 LGGRRGRKDRERERLEKERTEKERLEREKAERERLEKLRALEERSDWEGEGEEDHEGK 2558
+R ++R+R R E+E EK ++E +K ++ EK A++E + E+ EGK
Sbjct: 361 EEEKRAAEERQRARAEEE--EKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGK 416
Score = 49.3 bits (116), Expect = 1e-04
Identities = 51/215 (23%), Positives = 93/215 (43%), Gaps = 24/215 (11%)
Query: 2276 EKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRG-----IQQALRERKK 2330
E K+ +E R+ +G E E E + + +++ +A E E+L R +++ + RK+
Sbjct: 531 EAGKRLEELRRRRG--ETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQ 588
Query: 2331 REQERLAKEMQEK-KLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPL 2389
E +R +E +EK +L++E+ER++ E KR+ K + G ++ P K +
Sbjct: 589 EEADRKLREEEEKRRLKEEIERRRAEAAEKRQ-KMPEDGLSDDKKPFKCFTPKGSSL--- 644
Query: 2390 TKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPD 2449
K++ + E + + + +K K VS L Q EG S P
Sbjct: 645 -KIEERAEFLNKSV--------QKSSGVKSTHQAAIVSKIDSRLEQYTSAIEGTKSAKPT 695
Query: 2450 KQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPA 2484
K P + + V+NI W++ P A
Sbjct: 696 K---PAASDLPVPAEGVRNIKSMWEKGNVFSSPTA 727
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sapiens]
Length = 570
Score = 72.4 bits (176), Expect = 1e-11
Identities = 66/285 (23%), Positives = 135/285 (47%), Gaps = 24/285 (8%)
Query: 2281 EQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKREQERLAKEM 2340
+Q+E K EK +ER + + E+E +EEK+ R QE + E
Sbjct: 284 QQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKM---------------RRQEEMMWEK 328
Query: 2341 QEK-KLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKVDVKMETI 2399
+EK + Q+E+ +KEE + K +Q I+E+ ++ + ++ + + KM
Sbjct: 329 EEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ 388
Query: 2400 ERKISVREQTMSEKEE-LNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDK--QLAPKF 2456
E KI +E+ + E+EE + +++ MG+ ++ ++ E + +K + K
Sbjct: 389 EEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKI 448
Query: 2457 KTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRERERLE 2516
+ E +++ + ++ + K G Q +EA + +++ R+ K RE+E+
Sbjct: 449 REQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKM----RRQEEKIREQEKKI 504
Query: 2517 KERTEKERLEREKAERERLEKLRALEERSDWEGEGEEDHEGKKEK 2561
+E+ EK R E+E+ +E+ EK+ EE+ + E ++ E K +
Sbjct: 505 REQEEKIR-EQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRR 548
Score = 68.6 bits (166), Expect = 2e-10
Identities = 67/290 (23%), Positives = 145/290 (50%), Gaps = 43/290 (14%)
Query: 2272 MKAQEKAKKEQEE--RKHKGALEKEKERLQNMDEE--EYDALTEEEKLTFDRGIQQALRE 2327
M+ QE+ E+EE R+ + + +++E+++ ++E+ E + + E+E+ R ++ +RE
Sbjct: 318 MRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEE---KRQEEEKIRE 374
Query: 2328 RKKREQERLAKEMQEKKLQQELERQKEEDEL--KRRVKKGKQGPIKEEPPMKKSQAANKQ 2385
++KR+++ QE+K++++ E+ +E++E+ ++ K G+Q EE ++ + +Q
Sbjct: 375 QEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQ----EEKMWEQEEEMQEQ 430
Query: 2386 VPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNS 2445
+ + + K+ E+KI +E+ + E+EE+ +Q+QE+ G+
Sbjct: 431 EEKMRRQEEKIREQEKKIREQEEKIREQEEM-----------------MQEQEEKMGEQE 473
Query: 2446 KDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRR 2505
+Q A K + E ++ + + ++K Q EE E ++ Q +
Sbjct: 474 GKMCEQEA-KMQEQEEKMRRQEEKIREQEKKIREQ------EEKIREQEEMMQ-----EQ 521
Query: 2506 GRKDRERERLEKERTEKERLEREKAERERLEKLRALEERSDWEGEGEEDH 2555
K E+E E+ EK + + EK R+ EK+R E R + E ++H
Sbjct: 522 EEKMWEQEEKMCEQEEKMQEQEEKMRRQE-EKMREQEVRLRQQEEKMQEH 570
Score = 65.9 bits (159), Expect = 1e-09
Identities = 67/289 (23%), Positives = 133/289 (46%), Gaps = 26/289 (8%)
Query: 2283 EERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKREQERLAKEMQE 2342
EE K K A +EK +L ++ E +E K +R +++ + E + L KE+Q
Sbjct: 205 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 264
Query: 2343 KKLQQELERQKEEDELKRRVKKGKQGPI--KEEPPMKKSQAANKQVPPLTKVDVKMETIE 2400
+ +L+ Q EE+EL R+ + ++ + +EE ++ + +Q + + + KM E
Sbjct: 265 --VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQE 322
Query: 2401 RKISVREQTMSEKEEL---NKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQLAPKFK 2457
+ +E+ M +EE+ ++K + MH +++QE+ + K +++
Sbjct: 323 EMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE------ 376
Query: 2458 TYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDD--QRQVPLGGRRGRKDRERERL 2515
K + W +++ ++ EE E ++ Q Q G + K E+E
Sbjct: 377 ------KRQEQEAKMWRQEEKIR----EQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEE 426
Query: 2516 EKERTEKERLEREKAERERLEKLRALEERSDWEGEGEEDHEGKKEKDLG 2564
+E+ EK R + EK RE+ +K+R EE+ + E ++ E K + G
Sbjct: 427 MQEQEEKMRRQEEKI-REQEKKIREQEEKIREQEEMMQEQEEKMGEQEG 474
Score = 48.5 bits (114), Expect = 2e-04
Identities = 35/145 (24%), Positives = 77/145 (53%), Gaps = 10/145 (6%)
Query: 2265 MAQDYAAMKAQEKAKKEQEE--RKHKGALEKEKERLQNMDE---EEYDALTEEEKLTFDR 2319
M + M+ QE+ +EQE+ R+ + + +++E +Q +E E+ + E+E ++
Sbjct: 427 MQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQ 486
Query: 2320 GIQQALRERKKREQERLAKEMQEK-KLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKK 2378
+ +E K REQE+ +E +EK + Q+E+ +++EE ++ K +Q EE ++
Sbjct: 487 EEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQ----EEKMQEQ 542
Query: 2379 SQAANKQVPPLTKVDVKMETIERKI 2403
+ +Q + + +V++ E K+
Sbjct: 543 EEKMRRQEEKMREQEVRLRQQEEKM 567
Score = 45.1 bits (105), Expect = 0.002
Identities = 23/97 (23%), Positives = 57/97 (58%), Gaps = 6/97 (6%)
Query: 2265 MAQDYAAMKAQEKAKKEQEE--RKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQ 2322
M + A M+ QE+ + QEE R+ + + +++E+++ +E + E+E+ +++ +
Sbjct: 476 MCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEE----MMQEQEEKMWEQEEK 531
Query: 2323 QALRERKKREQERLAKEMQEKKLQQELERQKEEDELK 2359
+E K +EQE + +EK +QE+ +++E++++
Sbjct: 532 MCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQ 568
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 70.9 bits (172), Expect = 3e-11
Identities = 69/299 (23%), Positives = 146/299 (48%), Gaps = 32/299 (10%)
Query: 2265 MAQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQA 2324
M + M +E+ +E EE+ H E+EK R Q +E + + E+EK ++ +
Sbjct: 426 MRRQEEMMWEKEEKIRELEEKMH----EQEKIREQEEKRQEEEKIREQEKRQ-EQEAKMW 480
Query: 2325 LRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPI-KEEPPMKKSQAAN 2383
+E K REQE +E +EK +QE E+ E+++++ K+ +Q + ++E +++ +
Sbjct: 481 RQEEKIREQEEKIREQEEKMWRQE-EKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIW 539
Query: 2384 KQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGD 2443
+Q + + + K+ E K+ +E+ M ++EE K R + +++QE+
Sbjct: 540 RQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEE---KIREQEEKVWRQEEKIREQEE---- 592
Query: 2444 NSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGG 2503
K + E +++ + + + K G Q EE E +++ Q
Sbjct: 593 -----------KIREQEEKIREQEEMTQEQEEKMGEQ------EEKMCEQEEKMQEQEEK 635
Query: 2504 RRGRKDRERERLEKERTEKERL-EREKAERERLEKLRALEERSDWEGEGEEDHEGKKEK 2561
R ++++ RE+ +K R ++E++ E+E+ +E+ EK+ EE+ + E ++ E K +
Sbjct: 636 MRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRR 694
Score = 66.6 bits (161), Expect = 6e-10
Identities = 62/292 (21%), Positives = 138/292 (47%), Gaps = 10/292 (3%)
Query: 2272 MKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKR 2331
+ Q++ K ++E K + EK +E+ + + E+E +EEK+ + E+ +R
Sbjct: 355 LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRR 414
Query: 2332 EQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTK 2391
++E + ++ ++ + Q+E+ +KEE + K +Q I+E+ ++ + ++ +
Sbjct: 415 QEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQE 474
Query: 2392 VDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQ 2451
+ KM E KI +E+ + E+EE K + +H ++++E + ++
Sbjct: 475 QEAKMWRQEEKIREQEEKIREQEE----KMWRQEEKIHEQEKIREEEKRQEQEEMWRQEE 530
Query: 2452 LAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDD--QRQVPLGGRRGRKD 2509
K + E + + I ++ + + EE H+ ++ + Q R+ K
Sbjct: 531 ---KIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKI 587
Query: 2510 RERERLEKERTEKERLEREKAERERLEKLRALEERSDWEGEGEEDHEGKKEK 2561
RE+E +E+ EK R E+E+ +E+ EK+ EE+ + E ++ E K +
Sbjct: 588 REQEEKIREQEEKIR-EQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRR 638
Score = 64.3 bits (155), Expect = 3e-09
Identities = 61/283 (21%), Positives = 133/283 (46%), Gaps = 24/283 (8%)
Query: 2283 EERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKREQERLAKEMQE 2342
EE K K A +EK +L ++ E +E K +R +++ + E + L KE+Q
Sbjct: 278 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 337
Query: 2343 KKLQQELERQKEEDELKRRVKKGKQGPI--KEEPPMKKSQAANKQVPPLTKVDVKMETIE 2400
+ +L+ Q EE+EL R+ + ++ + +EE + + +Q + + + K+ E
Sbjct: 338 --VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQE 395
Query: 2401 RKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQLAPKFKTYE 2460
K+ +E+ M EKEE K R ++ ++ QE+ + + K + E
Sbjct: 396 EKMRRQEEMMWEKEE---KMRRQEEMMWEKEEKMRRQEEMMWEKEE--------KIRELE 444
Query: 2461 LTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRERERLEKERT 2520
+ + + I +++Q EE ++RQ ++++ RE+ EK R
Sbjct: 445 EKMHEQEKIREQEEKRQ---------EEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE 495
Query: 2521 EKERLEREKAERERLEKLRALEERSDWEGEGEEDHEGKKEKDL 2563
++E++ R++ + EK+R E+R + E ++ + ++++++
Sbjct: 496 QEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEI 538
Score = 61.6 bits (148), Expect = 2e-08
Identities = 63/317 (19%), Positives = 148/317 (46%), Gaps = 22/317 (6%)
Query: 2263 LNMAQDYAAMKAQEKAKK------EQEE--RKHKGALEKEKERLQNMDE---EEYDALTE 2311
LN Q+ + +EK ++ EQEE R+ + + +++E+++ +E E+ + +
Sbjct: 355 LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRR 414
Query: 2312 EEKLTFDRGIQQALRERKKREQERLAKEMQEKKLQQE-LERQKEEDELKRRVKKGKQGPI 2370
+E++ +++ + +E E+E +E++EK +QE + Q+E+ + + ++++ ++
Sbjct: 415 QEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQE 474
Query: 2371 KEEPPMKKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHG 2430
+E ++ + +Q + + + KM E KI +E+ E++ +++ + +
Sbjct: 475 QEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIRE 534
Query: 2431 LPLVQDQE----DSEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGM 2486
+ Q+ + E K +K + K ++ K + W +++ ++ +
Sbjct: 535 QEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKI 594
Query: 2487 EE-----APHEPDDQRQVPLGGRRGRKDRERERLEKERTEKERLEREKAERERLEKLRAL 2541
E E Q Q G + K E+E +E+ EK R + EK RE+ +K+R
Sbjct: 595 REQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKI-REQEKKIREQ 653
Query: 2542 EERSDWEGEGEEDHEGK 2558
EE+ + E ++ E K
Sbjct: 654 EEKIREQEEMMQEQEEK 670
Score = 55.8 bits (133), Expect = 1e-06
Identities = 39/151 (25%), Positives = 86/151 (56%), Gaps = 9/151 (5%)
Query: 2272 MKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKK- 2330
++ QE+ QEE+ H EK +E+ + + +E +EEK+ R ++ +RE+++
Sbjct: 552 IRKQEEKMWRQEEKMHDQE-EKIREQEEKVWRQEEKIREQEEKI---REQEEKIREQEEM 607
Query: 2331 -REQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPL 2389
+EQE E +EK +QE + Q++E++++R+ +K ++ +E+ ++ + +Q +
Sbjct: 608 TQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIRE---QEKKIREQEEKIREQEEMM 664
Query: 2390 TKVDVKMETIERKISVREQTMSEKEELNKKK 2420
+ + KM E K+ +E+ M E+EE +++
Sbjct: 665 QEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQ 695
Score = 52.0 bits (123), Expect = 2e-05
Identities = 45/186 (24%), Positives = 93/186 (50%), Gaps = 23/186 (12%)
Query: 2254 IGSREHIYILNMAQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEE 2313
I +E I Q+ M QE+ +EQEE + ++KE++ E+E +EE
Sbjct: 507 IHEQEKIREEEKRQEQEEMWRQEEKIREQEE------IWRQKEKIH---EQEEKIRKQEE 557
Query: 2314 KLTFDRGIQQALRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEE 2373
K+ +E K +QE +E +EK +QE + +++E++++ + +K ++ +EE
Sbjct: 558 KMW--------RQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIRE---QEE 606
Query: 2374 PPMKKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPL 2433
++ + +Q + + + KM+ E K+ +E+ + E+E KK R + +
Sbjct: 607 MTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQE---KKIREQEEKIREQEEM 663
Query: 2434 VQDQED 2439
+Q+QE+
Sbjct: 664 MQEQEE 669
Score = 51.2 bits (121), Expect = 3e-05
Identities = 36/141 (25%), Positives = 77/141 (54%), Gaps = 5/141 (3%)
Query: 2275 QEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKREQE 2334
QE+ +EQEE K + EK +E+ + E+E +EEK+ Q E+ +R++E
Sbjct: 583 QEEKIREQEE-KIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEE 641
Query: 2335 RLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKVDV 2394
++ + QEKK++++ E+ +E++E+ + ++ +EE ++ + +Q + + +
Sbjct: 642 KIRE--QEKKIREQEEKIREQEEMMQEQEEKMWE--QEEKMCEQEEKMQEQEEKMRRQEE 697
Query: 2395 KMETIERKISVREQTMSEKEE 2415
KM E ++ +E+ M E +E
Sbjct: 698 KMWEQEVRLRQQEEKMQEHQE 718
Score = 50.1 bits (118), Expect = 6e-05
Identities = 35/164 (21%), Positives = 90/164 (54%), Gaps = 14/164 (8%)
Query: 2267 QDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALR 2326
Q+ + +EK +++E+ + +++E+++ +E+ + E+E++T ++ + +
Sbjct: 569 QEEKIREQEEKVWRQEEK------IREQEEKIREQEEK----IREQEEMTQEQEEKMGEQ 618
Query: 2327 ERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQV 2386
E K EQE +E +EK +QE + +++E +++ + +K ++ +EE ++ + +Q
Sbjct: 619 EEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIRE---QEEMMQEQEEKMWEQE 675
Query: 2387 PPLTKVDVKMETIERKISVREQTMSEKE-ELNKKKRNMGDVSMH 2429
+ + + KM+ E K+ +E+ M E+E L +++ M + H
Sbjct: 676 EKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEH 719
Score = 45.1 bits (105), Expect = 0.002
Identities = 23/100 (23%), Positives = 59/100 (59%), Gaps = 5/100 (5%)
Query: 2265 MAQDYAAMKAQEKAKKEQEE--RKHKGALEKEKERLQNMDE---EEYDALTEEEKLTFDR 2319
M + M QE+ +EQEE R+ + + +++++++ +E E+ + + E+E+ +++
Sbjct: 615 MGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQ 674
Query: 2320 GIQQALRERKKREQERLAKEMQEKKLQQELERQKEEDELK 2359
+ +E K +EQE + +EK +QE+ +++E++++
Sbjct: 675 EEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 714
Score = 43.9 bits (102), Expect = 0.004
Identities = 28/93 (30%), Positives = 52/93 (55%), Gaps = 3/93 (3%)
Query: 2265 MAQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQA 2324
M + M+ QE+ +EQE +K + EK +E+ + M E+E +EEK+ Q
Sbjct: 629 MQEQEEKMRRQEEKIREQE-KKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 687
Query: 2325 LRERKKREQERLAKEMQEKKLQQELERQKEEDE 2357
E+ +R++E++ + QE +L+Q+ E+ +E E
Sbjct: 688 QEEKMRRQEEKMWE--QEVRLRQQEEKMQEHQE 718
Score = 41.2 bits (95), Expect = 0.027
Identities = 28/118 (23%), Positives = 59/118 (50%), Gaps = 1/118 (0%)
Query: 2265 MAQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQA 2324
M Q+ +++ K ++E K + EK + + + + E+E +EEK+ + Q
Sbjct: 607 MTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQE 666
Query: 2325 LRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAA 2382
+E K EQE E +EK +QE + +++E+++ + + +Q K + + +AA
Sbjct: 667 -QEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAA 723
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 70.1 bits (170), Expect = 5e-11
Identities = 67/297 (22%), Positives = 135/297 (45%), Gaps = 33/297 (11%)
Query: 2271 AMKAQEKAKKEQEERKHKGALEKEKERLQNMDEE-EYDALTEEEKLTFDRGIQQALRERK 2329
A K +E+ + +R+ + +KE+ER +N E E + E+E T DR ++ +
Sbjct: 155 AEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERG----R 210
Query: 2330 KREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPL 2389
+RE+ER + E+K Q + ER ++ + R K+ ++ E + + ++
Sbjct: 211 ERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDR 270
Query: 2390 TKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPD 2449
+ D + + ER+ + Q +E++ ++KR + Q + E + ++
Sbjct: 271 DR-DRRQKERERQTDRKRQRRTERDRETERKR-------------ERQRERERERERNRK 316
Query: 2450 KQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKD 2509
++ + + ++ + DR++ + E E + Q GR GR+
Sbjct: 317 RERERERERERERQRETER-----DREKERERKRKRQTEMDRERNRQT-----GREGRRQ 366
Query: 2510 RERER-LEKERTEKERLEREKAERER---LEKLRALEERSDWEGEGEEDHEGKKEKD 2562
ERER E+ER + ERE+ ER+R +K R + D +G+ E + + ++EKD
Sbjct: 367 AERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKD 423
Score = 67.4 bits (163), Expect = 3e-10
Identities = 72/292 (24%), Positives = 130/292 (44%), Gaps = 50/292 (17%)
Query: 2275 QEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKREQE 2334
+EK ++ Q +R+ EKE+ R + + E TE E +RG + +++RE++
Sbjct: 101 REKERERQTDRERDRQREKERNRQKERERE-----TEREG---ERGRDRQTDGQRERERQ 152
Query: 2335 RLAKEMQEKKLQQELERQKEEDELKRRVK-KGKQGPIKEEPPMKKSQAANKQVPPLTKVD 2393
R A++ +E++ +E +RQ E + K R + K +Q + E +K + +
Sbjct: 153 RDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRER 212
Query: 2394 VKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQE-DSEGDNSKDPDKQL 2452
+ E + + QT E++ K +R + ++ E D E + +D D+
Sbjct: 213 ERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDR 272
Query: 2453 APKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRER 2512
DR+Q +E + D +RQ RR +DRE
Sbjct: 273 ---------------------DRRQ---------KERERQTDRKRQ-----RRTERDRET 297
Query: 2513 ERLEKERTEKERLERE---KAERERLEKLRALEERSDWEGEGEEDHEGKKEK 2561
ER + + E+ER ERE K ERER E+ R E + + E + E++ E K+++
Sbjct: 298 ERKRERQRERER-ERERNRKRERER-ERERERERQRETERDREKERERKRKR 347
Score = 64.3 bits (155), Expect = 3e-09
Identities = 66/303 (21%), Positives = 137/303 (45%), Gaps = 27/303 (8%)
Query: 2273 KAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRER-KKR 2331
+A + A + ER + E+ +E+ Q E + EK + + R+R +++
Sbjct: 44 QAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREK 103
Query: 2332 EQERLAKEMQEKKLQQELERQKE-EDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLT 2390
E+ER ++++ ++E RQKE E E +R ++G+ + ++ + A K+ T
Sbjct: 104 ERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQT 163
Query: 2391 KVDVKMETIERKISVREQTMSEKE----ELNKKKRNMGD--VSMHGLPLVQDQE-DSEGD 2443
+ + +T + RE+ + +E E ++K N + S G +++E ++E +
Sbjct: 164 DRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETE 223
Query: 2444 NSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGG 2503
+ D++ + KT +R++ + A E + + +R+
Sbjct: 224 RKRQTDRERDRQRKTER-------------EREKQAERERASERETERDKERERERDRDR 270
Query: 2504 RRGRKDRERE----RLEKERTEKERLEREKAERERLEKLRALEERSDWEGEGEEDHEGKK 2559
R R+ +ERE R + RTE++R K ER+R E+ R E E E E + E ++
Sbjct: 271 DRDRRQKERERQTDRKRQRRTERDRETERKRERQR-ERERERERNRKRERERERERERER 329
Query: 2560 EKD 2562
+++
Sbjct: 330 QRE 332
Score = 47.4 bits (111), Expect = 4e-04
Identities = 63/298 (21%), Positives = 126/298 (42%), Gaps = 28/298 (9%)
Query: 2273 KAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDAL----TEEEKLTFDRGIQQALRER 2328
+A E+ + +ER+ + +++++R Q E + D TE ++ T + +Q RER
Sbjct: 250 RASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERER 309
Query: 2329 KKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPP 2388
+ RE+ R + +E++ ++E +R+ E D K R +K K+ + E ++++ ++
Sbjct: 310 E-RERNRKRERERERERERERQRETERDREKERERKRKR---QTEMDRERNRQTGREGRR 365
Query: 2389 LTKVDVKMETIERKISVREQTMSEKE---ELNKKKRNMGDVSMHGLPLVQDQEDSEGDNS 2445
+ + + E + S RE+ E++ + K++ + G + Q + E D
Sbjct: 366 QAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRE 425
Query: 2446 KDPDKQLAPKFKTYELTLKDVQNILMYWDRKQG---------VQLPPAGMEEAPHEPDDQ 2496
+ ++ + + + +D + DR+ G V PP + D
Sbjct: 426 SERGRERGREREKQKGRERDRER---QTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDPN 482
Query: 2497 RQVPLGGRRGRKDRERERLEKERTEKERLEREKAERERLEKLRALEER-SDWEGEGEE 2553
R P G R + E + R R KA R R+ R E R + G+G E
Sbjct: 483 R--PTRGIRWKSSPEDPKAASTRFPWGR--PAKASRGRVAGRRRWEPRLGEKRGQGGE 536
Score = 42.7 bits (99), Expect = 0.009
Identities = 30/119 (25%), Positives = 64/119 (53%), Gaps = 12/119 (10%)
Query: 2264 NMAQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQ 2323
N ++ + +E+ ++ + ER + E++++R MD E + T G +Q
Sbjct: 314 NRKRERERERERERERQRETERDREKERERKRKRQTEMDR-------ERNRQTGREGRRQ 366
Query: 2324 ALRER-KKREQER-LAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQ 2380
A RER ++RE++R A+E +E++ ++ +RQKE + R+ +K + G + E ++ +
Sbjct: 367 AERERERERERDRQSAREREERERDRDRDRQKERE---RQTEKDRDGQRETEKQREREK 422
Score = 39.3 bits (90), Expect = 0.10
Identities = 36/184 (19%), Positives = 80/184 (43%), Gaps = 14/184 (7%)
Query: 2268 DYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRE 2327
D + E+ ++ + +R+ + E+E+ER + + E E + +R ++ RE
Sbjct: 284 DRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERD-REKERE 342
Query: 2328 RKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVP 2387
RK++ Q + +E + ++ +E RQ E + + R + + +EE + + K+
Sbjct: 343 RKRKRQTEMDRE-RNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERE 401
Query: 2388 PLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKD 2447
T+ D + + +Q EK+ +++ R G + Q+ E D +
Sbjct: 402 RQTEKD-----RDGQRETEKQREREKDRESERGRERGRER-------EKQKGRERDRERQ 449
Query: 2448 PDKQ 2451
D+Q
Sbjct: 450 TDRQ 453
>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
theta, 150/170kDa [Homo sapiens]
Length = 1382
Score = 69.7 bits (169), Expect = 7e-11
Identities = 76/313 (24%), Positives = 137/313 (43%), Gaps = 39/313 (12%)
Query: 2258 EHIYILNMAQDYAAMKAQEKAKKEQEERKHKGALEKEK--ERLQNMDEEEYDALTEEEKL 2315
E I ++ A + +K + ++++EER LE+EK E M D +L
Sbjct: 705 EEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRL 764
Query: 2316 TFDRGIQQALRERKKREQERLAKE----MQEKKLQQELER------QKEEDELKRRVKKG 2365
R Q E+ K+ +ERLA+E ++E+K Q++ ER +KEE+E +R
Sbjct: 765 KAAR--QSVYEEKLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRR----A 818
Query: 2366 KQGPIKEEPPMKKSQAANKQ--VPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNM 2423
++ +KE ++++ A ++ + + K+E +ERK RE + E+E +++R +
Sbjct: 819 EEQMLKEREERERAERAKREEELREYQERVKKLEEVERKKRQRELEIEERERRREEERRL 878
Query: 2424 GDVSMHGLPLVQDQEDSEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPP 2483
GD S+ DSEG K P+ + E W R +G
Sbjct: 879 GDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPE----------KEWRRGEGRD--- 925
Query: 2484 AGMEEAPHEPDDQRQVPLGGRRGRKDRER---ERLEKERTEKERLEREKAERERLEKLRA 2540
E+ H D++R LG R+ R +R+ + + +R R E +R + A
Sbjct: 926 ---EDRSHRRDEERPRRLGDDEDREPSLRPDDDRVPRRGMDDDRGPRRGPEEDRFSRRGA 982
Query: 2541 LEERSDWEGEGEE 2553
++R W ++
Sbjct: 983 DDDRPSWRNTDDD 995
Score = 63.5 bits (153), Expect = 5e-09
Identities = 73/321 (22%), Positives = 148/321 (46%), Gaps = 28/321 (8%)
Query: 2261 YILNMAQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRG 2320
Y+ N +++ + A+ + +E++ER +++EKE L+ + E EE
Sbjct: 557 YLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQKVRKAEE------- 609
Query: 2321 IQQALRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQ 2380
++ +E K+RE+ER+ +E ++ K + ER ++ + + K K I++ +
Sbjct: 610 -ERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDF 668
Query: 2381 AANKQVPPLTK----VDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQD 2436
KQV L K + +++ E+KI E+ EE+ K + + + L +
Sbjct: 669 IMAKQVEQLEKEKKELQERLKNQEKKIDYFERA-KRLEEIPLIKSAYEEQRIKDMDLWEQ 727
Query: 2437 QEDS-------EGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEA 2489
QE+ E + + + +++ + +L + ++ ++ Q EE
Sbjct: 728 QEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEER 787
Query: 2490 PHEPDDQRQVPLGGRRGRKDRERERLEKERTE----KERLEREKAER-ERLEKLRALEER 2544
+ +++++ RR RE+E E+ R E KER ERE+AER +R E+LR +ER
Sbjct: 788 HNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQER 847
Query: 2545 SDWEGEGEEDHEGKKEKDLGV 2565
+ EE K++++L +
Sbjct: 848 VK---KLEEVERKKRQRELEI 865
Score = 59.7 bits (143), Expect = 7e-08
Identities = 79/355 (22%), Positives = 161/355 (45%), Gaps = 51/355 (14%)
Query: 2257 REHIYILNMAQDYAAMKAQE----KAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEE 2312
+E + LN+ ++ ++ +E K +K +EER + A E+EKER+ + E+ T
Sbjct: 579 KERLESLNIQREKEELEQREAELQKVRKAEEERLRQEAKEREKERILQ-EHEQIKKKTVR 637
Query: 2313 EKLTFDRGIQ---QALRERKKREQERLAKEMQEKKLQQELERQKEE--DELKRRVKK--- 2364
E+L + + +A ++ + E L + K ++LE++K+E + LK + KK
Sbjct: 638 ERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDY 697
Query: 2365 GKQGPIKEEPPMKKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMG 2424
++ EE P+ KS +++ + + + E ER +++ + E N+ R +
Sbjct: 698 FERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEE--ERITTMQLEREKALEHKNRMSRMLE 755
Query: 2425 DVSMHGLPLVQDQEDSEGDNSKDPDKQLAP----KFKTYELTLKDVQNILMYWDRKQGVQ 2480
D + + L ++ + K +++LA + + + K+ + I Y ++++ Q
Sbjct: 756 DRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQ 815
Query: 2481 LPPAGMEEAPHEPDDQRQVPLGGRRGRKDRERERLEKERTEKERLEREKAE-RERLEKLR 2539
RR + +ER E+ER E+ + E E E +ER++KL
Sbjct: 816 -----------------------RRAEEQMLKEREERERAERAKREEELREYQERVKKLE 852
Query: 2540 ALEERSDWEGEGEEDHEGKKEKD--LGVPFLDIQTP-----DFEGLSWKQALESD 2587
+E + E+ E ++E++ LG L + D EG +W++ E+D
Sbjct: 853 EVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWGDRDSEG-TWRKGPEAD 906
Score = 38.5 bits (88), Expect = 0.17
Identities = 58/269 (21%), Positives = 106/269 (39%), Gaps = 71/269 (26%)
Query: 2286 KHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKREQERLAKEMQEKKL 2345
K G EKEK R ++ +EE + +DR K+R+++ +E +K
Sbjct: 1174 KPGGWREKEKAREESWGPPRESRPSEERE--WDR--------EKERDRDNQDREENDKDP 1223
Query: 2346 QQELERQKE---EDELKRRVKKG--KQGPIKEEPPMKKSQAANKQVPPLTKVDVKMETIE 2400
++E +R+++ ED +R +G ++GP +E + S + +
Sbjct: 1224 ERERDRERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRD----------------D 1267
Query: 2401 RKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQLAPKFKTYE 2460
R R + ++ +L +++ D G PL ++E+ D
Sbjct: 1268 RDRDDRRRERDDRRDLRERRDLRDDRDRRGPPLRSEREEVSSWRRAD------------- 1314
Query: 2461 LTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRERERLEKERT 2520
DRK ++ E D R+VP +DRER+R +
Sbjct: 1315 -------------DRK----------DDRVEERDPPRRVPPPAL--SRDRERDRDREREG 1349
Query: 2521 EKERLEREKAERERLEKLRALEERSDWEG 2549
EKE+ +AE++R E LR + +D +G
Sbjct: 1350 EKEKAS-WRAEKDR-ESLRRTKNETDEDG 1376
Score = 33.5 bits (75), Expect = 5.6
Identities = 48/221 (21%), Positives = 80/221 (36%), Gaps = 50/221 (22%)
Query: 2349 LERQKEEDELKRRVKKGKQGP----IKEEPPMKKSQAANKQVPPLTKVDVKMETIERKIS 2404
L R+ ++D RR + GP +K +K +A + P
Sbjct: 1148 LSRRADDDRFPRRGDDSRPGPWRPLVKPGGWREKEKAREESWGP---------------- 1191
Query: 2405 VREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQLAPKFKTYELTLK 2464
RE SE+ E +++K D QD+E+++ D ++ D++ +
Sbjct: 1192 PRESRPSEEREWDREKERDRDN--------QDREENDKDPERERDRE------------R 1231
Query: 2465 DVQNILMYWDRKQGVQLP--PAGMEEAPHEPDDQ-RQVPLGGRRGRKDRERERLEKERTE 2521
DV DR+ + P G P E R R R DR RER ++
Sbjct: 1232 DV-------DREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLR 1284
Query: 2522 KERLEREKAERERLEKLRALEERSDWEGEGEEDHEGKKEKD 2562
+ R R+ +R EE S W + + +E+D
Sbjct: 1285 ERRDLRDDRDRRGPPLRSEREEVSSWRRADDRKDDRVEERD 1325
Score = 33.1 bits (74), Expect = 7.3
Identities = 31/107 (28%), Positives = 49/107 (45%), Gaps = 19/107 (17%)
Query: 2495 DQRQVPLGGRRGRKDRERERLEKERTEKERLERE------KAERERLEKLRALEERSDWE 2548
+QR+ L R + + ER R E + EKER+ +E K RERLE+++ E +
Sbjct: 595 EQREAELQKVR-KAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGA--- 650
Query: 2549 GEGEEDHEGKKEKDLGVPFLDIQTPDFEGLSWKQALESDKLPKGEQI 2595
K KD+ + L+ PDF + LE +K E++
Sbjct: 651 ---------KAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQERL 688
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 65.9 bits (159), Expect = 1e-09
Identities = 57/217 (26%), Positives = 109/217 (50%), Gaps = 21/217 (9%)
Query: 2276 EKAKKEQ--EERKHKGALEKEKERLQNMDEEEYDA-----LTEEEKLTFDRGIQQALRER 2328
EKAK+E+ EE+ K A K+ E ++ ++E +A L +EE+ +R Q+ L+++
Sbjct: 611 EKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEE---ERRHQELLQKK 667
Query: 2329 KKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPP 2388
K+ EQERL K + K+L ++ E+++ E E + + ++ ++ +E ++ A ++
Sbjct: 668 KEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRRE 727
Query: 2389 LTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDP 2448
++ + E ER+ ++R Q + EL +KK+ + L ++QE
Sbjct: 728 QERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKA------- 780
Query: 2449 DKQLAPKFKTYELTLKDVQN--ILMYWDRKQGVQLPP 2483
K+ A K +T+ DVQ+ Y QG + PP
Sbjct: 781 -KEAAGASKALNVTV-DVQSPACTSYQMTPQGHRAPP 815
Score = 64.3 bits (155), Expect = 3e-09
Identities = 65/298 (21%), Positives = 135/298 (45%), Gaps = 48/298 (16%)
Query: 2291 LEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKREQERLAKEMQEKKLQQELE 2350
+EKE++RL+N+ +E +K+ D+ ++ L E K + +ERL K +Q ++ ++++
Sbjct: 535 VEKERQRLENLRRKEEAEQLRRQKVEEDK--RRRLEEVKLKREERLRKVLQARERVEQMK 592
Query: 2351 RQKEED------ELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKVDVKMETIERKIS 2404
+K++ ++ + +K K+ + EE KK+ A + + + R +
Sbjct: 593 EEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQ 652
Query: 2405 VREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQLAPKFKTYELTLK 2464
E+ +E L KKK +E+ E K+LA + +
Sbjct: 653 QEEEERRHQELLQKKK----------------EEEQERLRKAAEAKRLAEQREQ------ 690
Query: 2465 DVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQV-PLGGRRGRKDRERERLEKERTEKE 2523
+R++ + E+ E + + Q L + R+++ER + E+E E+E
Sbjct: 691 ---------ERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQERE 741
Query: 2524 ---RLEREKAERERLEKLRALEERSDWEGEGEEDHEGKKEKDLGVP-----FLDIQTP 2573
RL++E+ +RE EK + E++ E + +E+ E K ++ G +D+Q+P
Sbjct: 742 KALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKALNVTVDVQSP 799
Score = 55.1 bits (131), Expect = 2e-06
Identities = 44/172 (25%), Positives = 87/172 (50%), Gaps = 25/172 (14%)
Query: 2265 MAQDYAAMKAQEKAKK------EQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFD 2318
M + A K +E+A++ E+EER+H+ L+K+KE E+E+L
Sbjct: 632 MEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEE-------------EQERL--- 675
Query: 2319 RGIQQALRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKK 2378
R +A R ++REQER +E +E++ +++ R++E E +R++ + ++ +E ++
Sbjct: 676 RKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAER 735
Query: 2379 SQAANKQVPPLTKVDVKMETIERKISVREQTMSEK---EELNKKKRNMGDVS 2427
++ L K ++ E E+K +Q ++E+ EE KK + S
Sbjct: 736 ELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGAS 787
Score = 46.2 bits (108), Expect = 8e-04
Identities = 37/126 (29%), Positives = 67/126 (53%), Gaps = 10/126 (7%)
Query: 2271 AMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKK 2330
A + E+ ++E+ E++ + +E+ER + E+ L E+E+ +Q A RE ++
Sbjct: 681 AKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQ-AERELQE 739
Query: 2331 REQE-RLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPL 2389
RE+ RL KE LQ+ELE +K+++E +R ++ ++EE K +AA
Sbjct: 740 REKALRLQKEQ----LQRELEEKKKKEEQQRLAER----QLQEEQEKKAKEAAGASKALN 791
Query: 2390 TKVDVK 2395
VDV+
Sbjct: 792 VTVDVQ 797
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 65.9 bits (159), Expect = 1e-09
Identities = 57/217 (26%), Positives = 109/217 (50%), Gaps = 21/217 (9%)
Query: 2276 EKAKKEQ--EERKHKGALEKEKERLQNMDEEEYDA-----LTEEEKLTFDRGIQQALRER 2328
EKAK+E+ EE+ K A K+ E ++ ++E +A L +EE+ +R Q+ L+++
Sbjct: 607 EKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEE---ERRHQELLQKK 663
Query: 2329 KKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPP 2388
K+ EQERL K + K+L ++ E+++ E E + + ++ ++ +E ++ A ++
Sbjct: 664 KEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRRE 723
Query: 2389 LTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDP 2448
++ + E ER+ ++R Q + EL +KK+ + L ++QE
Sbjct: 724 QERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKA------- 776
Query: 2449 DKQLAPKFKTYELTLKDVQN--ILMYWDRKQGVQLPP 2483
K+ A K +T+ DVQ+ Y QG + PP
Sbjct: 777 -KEAAGASKALNVTV-DVQSPACTSYQMTPQGHRAPP 811
Score = 63.9 bits (154), Expect = 4e-09
Identities = 65/297 (21%), Positives = 134/297 (45%), Gaps = 48/297 (16%)
Query: 2292 EKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKREQERLAKEMQEKKLQQELER 2351
EKE++RL+N+ +E +K+ D+ ++ L E K + +ERL K +Q ++ ++++
Sbjct: 532 EKERQRLENLRRKEEAEQLRRQKVEEDK--RRRLEEVKLKREERLRKVLQARERVEQMKE 589
Query: 2352 QKEED------ELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKVDVKMETIERKISV 2405
+K++ ++ + +K K+ + EE KK+ A + + + R +
Sbjct: 590 EKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQ 649
Query: 2406 REQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQLAPKFKTYELTLKD 2465
E+ +E L KKK +E+ E K+LA + +
Sbjct: 650 EEEERRHQELLQKKK----------------EEEQERLRKAAEAKRLAEQREQ------- 686
Query: 2466 VQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQV-PLGGRRGRKDRERERLEKERTEKE- 2523
+R++ + E+ E + + Q L + R+++ER + E+E E+E
Sbjct: 687 --------ERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREK 738
Query: 2524 --RLEREKAERERLEKLRALEERSDWEGEGEEDHEGKKEKDLGVP-----FLDIQTP 2573
RL++E+ +RE EK + E++ E + +E+ E K ++ G +D+Q+P
Sbjct: 739 ALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKALNVTVDVQSP 795
Score = 60.5 bits (145), Expect = 4e-08
Identities = 56/218 (25%), Positives = 110/218 (50%), Gaps = 32/218 (14%)
Query: 2329 KKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPP 2388
K++E++RL + ++ K+ ++L RQK E++ +RR+++ K +K E ++K A ++V
Sbjct: 531 KEKERQRL-ENLRRKEEAEQLRRQKVEEDKRRRLEEVK---LKREERLRKVLQARERVEQ 586
Query: 2389 LTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDP 2448
+ + K + IE+K + + EK E K++R L ++ K
Sbjct: 587 MK--EEKKKQIEQKFA----QIDEKTEKAKEER-----------LAEE---------KAK 620
Query: 2449 DKQLAPKFKTYELTLKDVQNI--LMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRG 2506
K A K + E K + L + +++ + +++ E ++ + +R
Sbjct: 621 KKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRL 680
Query: 2507 RKDRERERLEKERTEKERLEREKAERERLEKLRALEER 2544
+ RE+ER E+ER E+ER E+E+ E+ER E+ R L E+
Sbjct: 681 AEQREQERREQERREQERREQERREQERREQERQLAEQ 718
Score = 55.1 bits (131), Expect = 2e-06
Identities = 44/172 (25%), Positives = 87/172 (50%), Gaps = 25/172 (14%)
Query: 2265 MAQDYAAMKAQEKAKK------EQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFD 2318
M + A K +E+A++ E+EER+H+ L+K+KE E+E+L
Sbjct: 628 MEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEE-------------EQERL--- 671
Query: 2319 RGIQQALRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKK 2378
R +A R ++REQER +E +E++ +++ R++E E +R++ + ++ +E ++
Sbjct: 672 RKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAER 731
Query: 2379 SQAANKQVPPLTKVDVKMETIERKISVREQTMSEK---EELNKKKRNMGDVS 2427
++ L K ++ E E+K +Q ++E+ EE KK + S
Sbjct: 732 ELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGAS 783
Score = 46.2 bits (108), Expect = 8e-04
Identities = 37/126 (29%), Positives = 67/126 (53%), Gaps = 10/126 (7%)
Query: 2271 AMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKK 2330
A + E+ ++E+ E++ + +E+ER + E+ L E+E+ +Q A RE ++
Sbjct: 677 AKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQ-AERELQE 735
Query: 2331 REQE-RLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPL 2389
RE+ RL KE LQ+ELE +K+++E +R ++ ++EE K +AA
Sbjct: 736 REKALRLQKEQ----LQRELEEKKKKEEQQRLAER----QLQEEQEKKAKEAAGASKALN 787
Query: 2390 TKVDVK 2395
VDV+
Sbjct: 788 VTVDVQ 793
Score = 32.7 bits (73), Expect = 9.5
Identities = 27/113 (23%), Positives = 49/113 (43%), Gaps = 7/113 (6%)
Query: 2436 DQEDSEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDD 2495
D+E D P + P + ++ ++ + + P + +
Sbjct: 461 DEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFI 520
Query: 2496 QRQVPLGGRRGRKDRERERLE--KERTEKERLEREKAE---RERLEKLRALEE 2543
+R PL R K++ER+RLE + + E E+L R+K E R RLE+++ E
Sbjct: 521 KRNTPL--RMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKRE 571
>gi|15149465 caldesmon 1 isoform 5 [Homo sapiens]
Length = 532
Score = 65.5 bits (158), Expect = 1e-09
Identities = 80/336 (23%), Positives = 146/336 (43%), Gaps = 31/336 (9%)
Query: 2275 QEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKREQE 2334
QE+ +++QEE ++ + QN +E +A T + + A ER R +E
Sbjct: 41 QERLRQKQEEESLGQVTDQVEVNAQNSVPDE-EAKTTTTNTQVEGDDEAAFLERLARREE 99
Query: 2335 RLAKEMQEKKLQQELERQKEED------ELKRRVKKGKQGPIKEEPPMKKSQAANKQ--- 2385
R ++K+LQ+ LERQKE D L ++ + + E K+ ++ ++Q
Sbjct: 100 R-----RQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERY 154
Query: 2386 ----VPPLTKVDVKMETIERKISVREQTMSEKEELNKKKR-NMGDVSMHGLPLVQDQEDS 2440
+TK K + + + + +E E+EE K KR ++G+ + + +D+E
Sbjct: 155 EIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQIKDEKIKKDKEPK 214
Query: 2441 EGDNS-KDPDKQLAP------KFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEP 2493
E S D K +F T++L K +N + V A E AP
Sbjct: 215 EEVKSFMDRKKGFTEVKSQNGEFMTHKL--KHTENTFSRPGGRASVDTKEA--EGAPQVE 270
Query: 2494 DDQRQVPLGGRRGRKDRERERLEKERTEKERLEREKAERERLEKLRALEERSDWEGEGEE 2553
+R L RRG + E K++ ++ LE E+ +++R E+ + LEE + E
Sbjct: 271 AGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEA 330
Query: 2554 DHEGKKEKDLGVPFLDIQTPDFEGLSWKQALESDKL 2589
D + ++E++ +I+ E +Q + D L
Sbjct: 331 DRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGL 366
Score = 56.2 bits (134), Expect = 8e-07
Identities = 74/305 (24%), Positives = 132/305 (43%), Gaps = 40/305 (13%)
Query: 2268 DYAAMKAQEKAKKEQEERKHKGALEKEKE---------------RLQNMDEEEYDALTEE 2312
D AA + ++E+ +++ + ALE++KE R+QN D E + +E
Sbjct: 86 DEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQN-DTAENETTEKE 144
Query: 2313 EKLTFDRGIQQALRERKKREQERLAKEMQEKKLQQELERQKEEDELK--RRVKKGKQGPI 2370
EK ++ +ER + E+ + +K ++ E K+ED+ K +K K+G I
Sbjct: 145 EK-------SESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSI 197
Query: 2371 KEEPPMKKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHG 2430
E K + K P K +VK +K ++ + + +K K S G
Sbjct: 198 GEN--QIKDEKIKKDKEP--KEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPG 253
Query: 2431 LPLVQDQEDSEGDNSKDPDKQLAP-KFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEA 2489
D +++EG + K+L + + E ++ + + KQ Q +EE
Sbjct: 254 GRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKL------KQKQQEAALELEEL 307
Query: 2490 PHEPDDQRQVPLGGRRGRKDRERERLEKERTEKERLEREKAERERLEKLRALEERSDWEG 2549
+ +++R+V + RK E +R +E EK RL +E+ ER R E A E+R
Sbjct: 308 KKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRL-KEEIERRRAE---AAEKRQKMPE 363
Query: 2550 EGEED 2554
+G D
Sbjct: 364 DGLSD 368
Score = 49.3 bits (116), Expect = 1e-04
Identities = 51/215 (23%), Positives = 93/215 (43%), Gaps = 24/215 (11%)
Query: 2276 EKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRG-----IQQALRERKK 2330
E K+ +E R+ +G E E E + + +++ +A E E+L R +++ + RK+
Sbjct: 270 EAGKRLEELRRRRG--ETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQ 327
Query: 2331 REQERLAKEMQEK-KLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPL 2389
E +R +E +EK +L++E+ER++ E KR+ K + G ++ P K +
Sbjct: 328 EEADRKLREEEEKRRLKEEIERRRAEAAEKRQ-KMPEDGLSDDKKPFKCFTPKGSSL--- 383
Query: 2390 TKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPD 2449
K++ + E + + + +K K VS L Q EG S P
Sbjct: 384 -KIEERAEFLNKSV--------QKSSGVKSTHQAAIVSKIDSRLEQYTSAIEGTKSAKPT 434
Query: 2450 KQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPA 2484
K P + + V+NI W++ P A
Sbjct: 435 K---PAASDLPVPAEGVRNIKSMWEKGNVFSSPTA 466
Score = 44.7 bits (104), Expect = 0.002
Identities = 63/301 (20%), Positives = 134/301 (44%), Gaps = 37/301 (12%)
Query: 2321 IQQALRERKKREQERLAKEMQEKKLQQELERQKEEDELKR---RVKKGKQGPIKEEPPMK 2377
+ Q +R ++E A+E + + Q+ L +++EE+ L + +V+ Q + +E
Sbjct: 16 LSQIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEE--A 73
Query: 2378 KSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKK-KRNMGDVSMHGLPLVQD 2436
K+ N QV + +E + R+ R++ + E E K+ + D S+ LP +
Sbjct: 74 KTTTTNTQVEGDDEA-AFLERLARREERRQKRLQEALERQKEFDPTITDASL-SLPSRRM 131
Query: 2437 QEDSEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQ 2496
Q D+ + + + +++ + + YE +++ + + + +K + +E + +++
Sbjct: 132 QNDTAENETTEKEEKSESRQERYE--IEETETVTKSY-QKNDWRDAEENKKEDKEKEEEE 188
Query: 2497 RQVPLGGRRGRKDRERERLEKERTEKER----LEREKAERE--------RLEKLRALEER 2544
+ P G G + E+++K++ KE ++R+K E KL+ E
Sbjct: 189 EEKPKRGSIGENQIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENT 248
Query: 2545 ----------SDWEGEGEEDHE-GKKEKDLGVPFLDIQTPDFEGLSWKQ---ALESDKLP 2590
E EG E GK+ ++L + ++ +FE L KQ ALE ++L
Sbjct: 249 FSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELK 308
Query: 2591 K 2591
K
Sbjct: 309 K 309
Score = 41.2 bits (95), Expect = 0.027
Identities = 52/224 (23%), Positives = 93/224 (41%), Gaps = 39/224 (17%)
Query: 2261 YILNMAQDYAAMKAQEKAKKEQEERKHK------GALEKEKERLQNMDEEEYDALTEEEK 2314
Y N +D K ++K K+E+EE K K ++ EK + +EE + + +K
Sbjct: 166 YQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQIKDEKIKKDKEPKEEVKSFMDRKK 225
Query: 2315 ---------------------LTFDRGIQQALRERKKREQERLAKEMQEKKLQQELERQK 2353
TF R +A + K+ E A +++ K +EL R++
Sbjct: 226 GFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEG---APQVEAGKRLEELRRRR 282
Query: 2354 EEDELK--RRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKVDVKMETIERKISVREQTMS 2411
E E + ++K+ +Q E +KK + ++V + K E +RK+ E+
Sbjct: 283 GETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRR 342
Query: 2412 EKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQLAPK 2455
KEE+ +++ + +P ED D+ K P K PK
Sbjct: 343 LKEEIERRRAEAAE-KRQKMP-----EDGLSDDKK-PFKCFTPK 379
>gi|4826657 caldesmon 1 isoform 2 [Homo sapiens]
Length = 538
Score = 65.5 bits (158), Expect = 1e-09
Identities = 80/336 (23%), Positives = 146/336 (43%), Gaps = 31/336 (9%)
Query: 2275 QEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKREQE 2334
QE+ +++QEE ++ + QN +E +A T + + A ER R +E
Sbjct: 47 QERLRQKQEEESLGQVTDQVEVNAQNSVPDE-EAKTTTTNTQVEGDDEAAFLERLARREE 105
Query: 2335 RLAKEMQEKKLQQELERQKEED------ELKRRVKKGKQGPIKEEPPMKKSQAANKQ--- 2385
R ++K+LQ+ LERQKE D L ++ + + E K+ ++ ++Q
Sbjct: 106 R-----RQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERY 160
Query: 2386 ----VPPLTKVDVKMETIERKISVREQTMSEKEELNKKKR-NMGDVSMHGLPLVQDQEDS 2440
+TK K + + + + +E E+EE K KR ++G+ + + +D+E
Sbjct: 161 EIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQIKDEKIKKDKEPK 220
Query: 2441 EGDNS-KDPDKQLAP------KFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEP 2493
E S D K +F T++L K +N + V A E AP
Sbjct: 221 EEVKSFMDRKKGFTEVKSQNGEFMTHKL--KHTENTFSRPGGRASVDTKEA--EGAPQVE 276
Query: 2494 DDQRQVPLGGRRGRKDRERERLEKERTEKERLEREKAERERLEKLRALEERSDWEGEGEE 2553
+R L RRG + E K++ ++ LE E+ +++R E+ + LEE + E
Sbjct: 277 AGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEA 336
Query: 2554 DHEGKKEKDLGVPFLDIQTPDFEGLSWKQALESDKL 2589
D + ++E++ +I+ E +Q + D L
Sbjct: 337 DRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGL 372
Score = 56.2 bits (134), Expect = 8e-07
Identities = 74/305 (24%), Positives = 132/305 (43%), Gaps = 40/305 (13%)
Query: 2268 DYAAMKAQEKAKKEQEERKHKGALEKEKE---------------RLQNMDEEEYDALTEE 2312
D AA + ++E+ +++ + ALE++KE R+QN D E + +E
Sbjct: 92 DEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQN-DTAENETTEKE 150
Query: 2313 EKLTFDRGIQQALRERKKREQERLAKEMQEKKLQQELERQKEEDELK--RRVKKGKQGPI 2370
EK ++ +ER + E+ + +K ++ E K+ED+ K +K K+G I
Sbjct: 151 EK-------SESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSI 203
Query: 2371 KEEPPMKKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHG 2430
E K + K P K +VK +K ++ + + +K K S G
Sbjct: 204 GEN--QIKDEKIKKDKEP--KEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPG 259
Query: 2431 LPLVQDQEDSEGDNSKDPDKQLAP-KFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEA 2489
D +++EG + K+L + + E ++ + + KQ Q +EE
Sbjct: 260 GRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKL------KQKQQEAALELEEL 313
Query: 2490 PHEPDDQRQVPLGGRRGRKDRERERLEKERTEKERLEREKAERERLEKLRALEERSDWEG 2549
+ +++R+V + RK E +R +E EK RL +E+ ER R E A E+R
Sbjct: 314 KKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRL-KEEIERRRAE---AAEKRQKMPE 369
Query: 2550 EGEED 2554
+G D
Sbjct: 370 DGLSD 374
Score = 49.3 bits (116), Expect = 1e-04
Identities = 51/215 (23%), Positives = 93/215 (43%), Gaps = 24/215 (11%)
Query: 2276 EKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRG-----IQQALRERKK 2330
E K+ +E R+ +G E E E + + +++ +A E E+L R +++ + RK+
Sbjct: 276 EAGKRLEELRRRRG--ETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQ 333
Query: 2331 REQERLAKEMQEK-KLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPL 2389
E +R +E +EK +L++E+ER++ E KR+ K + G ++ P K +
Sbjct: 334 EEADRKLREEEEKRRLKEEIERRRAEAAEKRQ-KMPEDGLSDDKKPFKCFTPKGSSL--- 389
Query: 2390 TKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPD 2449
K++ + E + + + +K K VS L Q EG S P
Sbjct: 390 -KIEERAEFLNKSV--------QKSSGVKSTHQAAIVSKIDSRLEQYTSAIEGTKSAKPT 440
Query: 2450 KQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPA 2484
K P + + V+NI W++ P A
Sbjct: 441 K---PAASDLPVPAEGVRNIKSMWEKGNVFSSPTA 472
Score = 41.2 bits (95), Expect = 0.027
Identities = 52/224 (23%), Positives = 93/224 (41%), Gaps = 39/224 (17%)
Query: 2261 YILNMAQDYAAMKAQEKAKKEQEERKHK------GALEKEKERLQNMDEEEYDALTEEEK 2314
Y N +D K ++K K+E+EE K K ++ EK + +EE + + +K
Sbjct: 172 YQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQIKDEKIKKDKEPKEEVKSFMDRKK 231
Query: 2315 ---------------------LTFDRGIQQALRERKKREQERLAKEMQEKKLQQELERQK 2353
TF R +A + K+ E A +++ K +EL R++
Sbjct: 232 GFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEG---APQVEAGKRLEELRRRR 288
Query: 2354 EEDELK--RRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKVDVKMETIERKISVREQTMS 2411
E E + ++K+ +Q E +KK + ++V + K E +RK+ E+
Sbjct: 289 GETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRR 348
Query: 2412 EKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQLAPK 2455
KEE+ +++ + +P ED D+ K P K PK
Sbjct: 349 LKEEIERRRAEAAE-KRQKMP-----EDGLSDDKK-PFKCFTPK 385
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 65.1 bits (157), Expect = 2e-09
Identities = 37/148 (25%), Positives = 79/148 (53%), Gaps = 10/148 (6%)
Query: 2273 KAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKRE 2332
+ +EK K++++E+K +G KE + + +E + + E E+ +R ++ +ERKKRE
Sbjct: 108 EGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRE 167
Query: 2333 QERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKV 2392
++++ ++ +E+K ++ ER+K E K R K+ ++ +E +K + K
Sbjct: 168 RKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERK-------- 219
Query: 2393 DVKMETIERKISVREQTMSEKEELNKKK 2420
K +R+ + RE+ ++E +KK
Sbjct: 220 --KERQKDRQTNWREKERGKRERKERKK 245
Score = 64.3 bits (155), Expect = 3e-09
Identities = 70/251 (27%), Positives = 115/251 (45%), Gaps = 70/251 (27%)
Query: 2320 GIQQALRERKK----REQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPP 2375
G Q +RER++ R++ + +E + KK ++E E++K E E +R+ ++GK KE+
Sbjct: 33 GWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGK----KEK-- 86
Query: 2376 MKKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQ 2435
K + K E ERK RE+ E EE K+K+
Sbjct: 87 ---------------KGERKKEERERKKRRREKENKEGEEKEKRKKK------------- 118
Query: 2436 DQEDSEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDD 2495
++ G SK+ ++ + + E +RK+ E E +
Sbjct: 119 -EKKERGRTSKEGKERERKEERKRE-------------ERKE--------RERKKEEREK 156
Query: 2496 QRQVPLGGRRGRKDRERERL---EKERTEKERLEREKAERERLE--KLRALEERSDWEGE 2550
+R+ R+ RK RER+++ E+ER EKER ER+K ER R E K R +ER + + E
Sbjct: 157 ERE-----RKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKE 211
Query: 2551 GEEDHEGKKEK 2561
++ E KKE+
Sbjct: 212 RKKKEERKKER 222
Score = 63.2 bits (152), Expect = 7e-09
Identities = 56/257 (21%), Positives = 115/257 (44%), Gaps = 46/257 (17%)
Query: 2273 KAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKRE 2332
+++ + ++ + E + +G E+E ER + E E E++ +RG ++ ERKK E
Sbjct: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE 94
Query: 2333 QERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKV 2392
+ER + +++ + E + ++++ E K R + K+G +E +K + ++
Sbjct: 95 RERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKER------- 147
Query: 2393 DVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQL 2452
ERK RE+ KE ++++ +G+ +++E E + + ++
Sbjct: 148 -------ERKKEEREKERERKERKKRERKQVGE---------KEEERKEKERKERKKRER 191
Query: 2453 APKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRER 2512
K + E K+ + +RK+ + E +RQ KDR+
Sbjct: 192 NRKERKKERERKERR------ERKK--------ERKKKEERKKERQ---------KDRQT 228
Query: 2513 ERLEKERTEKERLEREK 2529
EKER ++ER ER+K
Sbjct: 229 NWREKERGKRERKERKK 245
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 65.1 bits (157), Expect = 2e-09
Identities = 43/190 (22%), Positives = 98/190 (51%), Gaps = 10/190 (5%)
Query: 2265 MAQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQA 2324
M ++ A +A+ +A++E E R+ + E+E ++EE + L ++++ R ++A
Sbjct: 631 MREEQLAREAEARAEREAEARRRE---EQEAREKAQAEQEEQERLQKQKEEAEARSREEA 687
Query: 2325 LRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANK 2384
R+R +RE K Q+++ Q+ ER+K +E+ +R +K + K++ K++ A
Sbjct: 688 ERQRLERE-----KHFQQQE-QERQERRKRLEEIMKRTRKSEVSETKQKQDSKEANANGS 741
Query: 2385 QVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGL-PLVQDQEDSEGD 2443
P+ V+ + ++++ +E+ + ++ + + + + ++GL PL QE+
Sbjct: 742 SPEPVKAVEARSPGLQKEAVQKEEPIPQEPQWSLPSKELPASLVNGLQPLPAHQENGFST 801
Query: 2444 NSKDPDKQLA 2453
N DK L+
Sbjct: 802 NGPSGDKSLS 811
Score = 41.6 bits (96), Expect = 0.020
Identities = 35/105 (33%), Positives = 61/105 (58%), Gaps = 13/105 (12%)
Query: 2271 AMKAQEKAKKEQEERK----HKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALR 2326
A+ A + +QE +K HK A E+ +ER + + ++ L +EEK R ++ L+
Sbjct: 119 AVPASDSPPTKQEVKKAGERHKLAKERREERAKYLAAKKAVWLEKEEKAKALR--EKQLQ 176
Query: 2327 ERKKR-EQERLAKEMQ----EKKLQQELERQKE--EDELKRRVKK 2364
ER++R E++RL E + E++ +Q+LE+ KE E ++R VKK
Sbjct: 177 ERRRRLEEQRLKAEQRRAALEERQRQKLEKNKERYEAAIQRSVKK 221
Score = 39.7 bits (91), Expect = 0.078
Identities = 30/151 (19%), Positives = 71/151 (47%), Gaps = 14/151 (9%)
Query: 2302 DEEEYDALTEEEKLTFDRGIQQALRERKKREQERLA-----KEMQEKKLQQELE--RQKE 2354
D EE L E++ +QA +R++ EQER K M+E++L +E E ++E
Sbjct: 595 DREEATRLLAEKR-------RQAREQREREEQERRLQAERDKRMREEQLAREAEARAERE 647
Query: 2355 EDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKE 2414
+ +R ++ ++ E+ ++ Q ++ ++ + + + +ER+ ++Q +E
Sbjct: 648 AEARRREEQEAREKAQAEQEEQERLQKQKEEAEARSREEAERQRLEREKHFQQQEQERQE 707
Query: 2415 ELNKKKRNMGDVSMHGLPLVQDQEDSEGDNS 2445
+ + M + + ++DS+ N+
Sbjct: 708 RRKRLEEIMKRTRKSEVSETKQKQDSKEANA 738
Score = 36.6 bits (83), Expect = 0.66
Identities = 18/75 (24%), Positives = 39/75 (52%)
Query: 2487 EEAPHEPDDQRQVPLGGRRGRKDRERERLEKERTEKERLEREKAERERLEKLRALEERSD 2546
E+ E + + + RR + RE+ + E+ E+ERL+++K E E + A +R +
Sbjct: 634 EQLAREAEARAEREAEARRREEQEAREKAQAEQEEQERLQKQKEEAEARSREEAERQRLE 693
Query: 2547 WEGEGEEDHEGKKEK 2561
E ++ + ++E+
Sbjct: 694 REKHFQQQEQERQER 708
Score = 35.8 bits (81), Expect = 1.1
Identities = 47/236 (19%), Positives = 94/236 (39%), Gaps = 31/236 (13%)
Query: 2369 PIKEEPPMKKSQAAN------KQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRN 2422
P KE+PP + A PP+T T +R+ + R ++EK +++R
Sbjct: 558 PQKEQPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTTDREEATR--LLAEKRRQAREQR- 614
Query: 2423 MGDVSMHGLPLVQDQEDSEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLP 2482
++E+ E + DK++ + E + + R++ +
Sbjct: 615 -------------EREEQERRLQAERDKRMREEQLAREAEARAEREAEAR--RREEQEAR 659
Query: 2483 PAGMEEAPHEPDDQRQVPLGGRRGRKDRERERLEKER----TEKERLEREKAERERLEKL 2538
E + Q+Q R R++ ER+RLE+E+ E+ER ER K E +++
Sbjct: 660 EKAQAEQEEQERLQKQKEEAEARSREEAERQRLEREKHFQQQEQERQERRKRLEEIMKRT 719
Query: 2539 RALEERSDWEGEGEEDHEGKKEKDLGVPFLDIQTPDFEGLSWKQALESDKLPKGEQ 2594
R E + + ++ V ++ ++P GL + + + +P+ Q
Sbjct: 720 RKSEVSETKQKQDSKEANANGSSPEPVKAVEARSP---GLQKEAVQKEEPIPQEPQ 772
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 64.7 bits (156), Expect = 2e-09
Identities = 65/301 (21%), Positives = 145/301 (48%), Gaps = 29/301 (9%)
Query: 2272 MKAQEKAKKEQEERKHKGALEKEKERLQNMDE--EEYDALTEEEKLTFDRGIQQALRERK 2329
++ QEK QEE+ H+ +E+E+ Q +E + + + E+E++ + E+
Sbjct: 446 IREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKI 505
Query: 2330 KREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPI-KEEPPMK------KSQAA 2382
++++E++ ++ ++ + Q+E R++EE ++ K +Q + +EE M + +
Sbjct: 506 RKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKR 565
Query: 2383 NKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEG 2442
+Q + + + K+ E K+ +E+ + E+EE K++ + +++QE+
Sbjct: 566 QEQEDKMWRQEEKIREQEEKVWRQEEKIREQEE---KRQEQEEKMWKQEEKIREQEEKIQ 622
Query: 2443 DNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDD--QRQVP 2500
+ + K + E +++ + + + K G Q EE E ++ Q Q
Sbjct: 623 EQEE--------KIREQEEKIREQEEMTQEQEEKMGEQ------EEKMCEQEEKMQEQEE 668
Query: 2501 LGGRRGRKDRERERLEKERTEKERLEREKAERERLEKLRALEERSDWEGEGEEDHEGKKE 2560
R+ K RE+E+ +E+ EK R E+E+ +E+ EK+ EE+ + E ++ E K
Sbjct: 669 TMWRQEEKIREQEKKIREQEEKIR-EQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMR 727
Query: 2561 K 2561
+
Sbjct: 728 R 728
Score = 63.9 bits (154), Expect = 4e-09
Identities = 67/306 (21%), Positives = 139/306 (45%), Gaps = 38/306 (12%)
Query: 2263 LNMAQDYAAMKAQEKAKK-----EQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTF 2317
LN Q+ + +EK ++ +++E K + EK +E+ + M +E +EEK+
Sbjct: 294 LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRR 353
Query: 2318 DRGIQQALRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMK 2377
+ E+ +R++E + ++ ++ + Q+E+ +KEE + K +Q I+E+ +
Sbjct: 354 QEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKR 413
Query: 2378 KSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQ 2437
+ + ++ + + KM E KI +E+ + E+E KK + +H ++++
Sbjct: 414 QEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQE----KKMWRQEEKIHEQEKIREE 469
Query: 2438 EDSEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDD-- 2495
E +Q + E + + + I W +K E HE ++
Sbjct: 470 E----------KRQEQEEMWRQEEKIHEQEEI---WRQK-----------EKMHEQEEKI 505
Query: 2496 QRQVPLGGRRGRKDRERERLEKERTEKERLEREK-AERERL--EKLRALEERSDWEGEGE 2552
++Q R+ K RE+E +E+ EK + EK E+E + E+ + E+ WE E
Sbjct: 506 RKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKR 565
Query: 2553 EDHEGK 2558
++ E K
Sbjct: 566 QEQEDK 571
Score = 63.2 bits (152), Expect = 7e-09
Identities = 69/316 (21%), Positives = 150/316 (47%), Gaps = 57/316 (18%)
Query: 2254 IGSREHIYILNMAQDYAAMKAQEKAKKEQEER-KHKGALEKEKERLQNMDEEEY---DAL 2309
I +E I Q+ M QE+ EQEE + K + +++E+++ +E+ + + +
Sbjct: 460 IHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKI 519
Query: 2310 TEEEKLTFDRGIQQALRERKKREQERLAKEMQ----EKKLQQELERQKEEDELKRRVKKG 2365
E+E+ ++ + +E K REQE + +E + ++K+ +E +RQ++ED++ R+ +K
Sbjct: 520 REQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKI 579
Query: 2366 KQGPIK-----------EEPPMKKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKE 2414
++ K EE ++ + KQ + + + K++ E KI +E+ + E+E
Sbjct: 580 REQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQE 639
Query: 2415 ELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWD 2474
E + Q+QE+ G+ + +Q K + E T+ W
Sbjct: 640 E-----------------MTQEQEEKMGEQEEKMCEQ-EEKMQEQEETM---------WR 672
Query: 2475 RKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRERERLEKERTEKERLEREKAERER 2534
+++ ++ + E + +Q ++ +++E + E+ E++ E+E+ +E+
Sbjct: 673 QEEKIREQEKKIREQEEKIREQEEM-------MQEQEEKMWEQ---EEKMCEQEEKMQEQ 722
Query: 2535 LEKLRALEERSDWEGE 2550
EK+R EE+ WE E
Sbjct: 723 EEKMRRQEEKM-WEQE 737
Score = 62.0 bits (149), Expect = 1e-08
Identities = 58/286 (20%), Positives = 135/286 (47%), Gaps = 16/286 (5%)
Query: 2283 EERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKREQERLAKEMQE 2342
EE K K A +EK +L ++ E +E K +R +++ + E + L KE+Q
Sbjct: 217 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 276
Query: 2343 KKLQQELERQKEEDELKRRVKKGKQGPI--KEEPPMKKSQAANKQVPPLTKVDVKMETIE 2400
+ +L+ Q EE+EL R+ + ++ + +EE + + +Q + + + K+ E
Sbjct: 277 --VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQE 334
Query: 2401 RKISVREQTMSEKEELNKKKRNM---GDVSMHGLPLVQDQEDSEGDNSKDPDKQLAPKFK 2457
K+ +E+ M EKEE +++ M + M + +++ + ++ + K +
Sbjct: 335 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIR 394
Query: 2458 TYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRERERLEK 2517
E + + + I +++Q EE ++RQ ++++ RE+ EK
Sbjct: 395 ELEEKMHEQEKIREQEEKRQ---------EEEKIREQEKRQEQEAKMWRQEEKIREQEEK 445
Query: 2518 ERTEKERLEREKAERERLEKLRALEERSDWEGEGEEDHEGKKEKDL 2563
R +++++ R++ + EK+R E+R + E ++ + +++++
Sbjct: 446 IREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEI 491
Score = 41.6 bits (96), Expect = 0.020
Identities = 22/97 (22%), Positives = 56/97 (57%), Gaps = 6/97 (6%)
Query: 2265 MAQDYAAMKAQEKAKKEQEE--RKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQ 2322
M + M+ QE+ QEE R+ + + +++E+++ E+ + + E+E+ +++ +
Sbjct: 656 MCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIR----EQEEMMQEQEEKMWEQEEK 711
Query: 2323 QALRERKKREQERLAKEMQEKKLQQELERQKEEDELK 2359
+E K +EQE + +EK +QE+ +++E++++
Sbjct: 712 MCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 748
Score = 37.0 bits (84), Expect = 0.50
Identities = 30/90 (33%), Positives = 47/90 (52%), Gaps = 3/90 (3%)
Query: 2265 MAQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQA 2324
M + M QE+ +EQE +K + EK +E+ + M E+E +EEK+ Q
Sbjct: 663 MQEQEETMWRQEEKIREQE-KKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 721
Query: 2325 LRERKKREQERLAKEMQEKKLQQELERQKE 2354
+E K R QE E QE +L+Q+ E+ +E
Sbjct: 722 -QEEKMRRQEEKMWE-QEVRLRQQEEKMQE 749
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 64.3 bits (155), Expect = 3e-09
Identities = 82/310 (26%), Positives = 129/310 (41%), Gaps = 72/310 (23%)
Query: 2273 KAQEKAKKEQEERK--HKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKK 2330
K EK +KE+E++K K ++ +E L + EEE EEE +R + E K+
Sbjct: 321 KKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEE----ERIKRLEELEAKR 376
Query: 2331 REQERLAKEMQEKKLQQELERQ---KEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVP 2387
+E+ERL +E +E+K Q+E ER+ K+E +L K ++ + E +K QA +VP
Sbjct: 377 KEEERLEQEKRERKKQKEKERKERLKKEGKL--LTKSQREARARAEATLKLLQAQGVEVP 434
Query: 2388 PLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKD 2447
K+ L KK+ P+ +D++ K
Sbjct: 435 ------------------------SKDSLPKKR-----------PIYEDKK------RKK 453
Query: 2448 PDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGG---- 2503
+QL K + + L ++ +QGV P P EP+++ G
Sbjct: 454 IPQQLESKEVSESMELCAAVEVM-----EQGV--PEKEETPPPVEPEEEEDTEDAGLDDW 506
Query: 2504 RRGRKDRERERLEKERTE---KERLEREKAERERLEKLRALEERSDWEGEG------EED 2554
D E E++E + KE E E+ E E E+ EE + EGE EED
Sbjct: 507 EAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEED 566
Query: 2555 HEGKKEKDLG 2564
+ EKD G
Sbjct: 567 EKVSDEKDSG 576
Score = 62.4 bits (150), Expect = 1e-08
Identities = 73/324 (22%), Positives = 146/324 (45%), Gaps = 33/324 (10%)
Query: 2267 QDYAAMKAQEKAKKE--QEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQA 2324
++ A+K E ++E +++K KG K K+ + D EE + + K T ++
Sbjct: 76 RETVAVKPTENNEEEFTSKDKKKKGQKGK-KQSFDDNDSEELEDKDSKSKKTAKPKVEMY 134
Query: 2325 LRERKKREQERLAKEMQEK--KLQQELERQKEEDELKRRVKK-------GKQGPIKEE-P 2374
+ +L K+ + K K ++ + +E+++ +++K+ G+ G +E
Sbjct: 135 SGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFL 194
Query: 2375 PMKKSQAANKQVPPLTKVDVKMETIER--KISVREQTMSEKEELNKKKRNMGDVSMHGLP 2432
+K Q N++ P ++ E + KI Q +EK+E +KKR+ + L
Sbjct: 195 QSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLK 254
Query: 2433 LVQDQEDSEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHE 2492
++ E + D SK + Q KF+ + K + + ++ + P A ++ +
Sbjct: 255 EKEELETGKKDQSKQKESQ--RKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGD 312
Query: 2493 PDDQRQVPLGGRRGRKDRER-------------ERLEKERTEKERLEREKAER-ERLEKL 2538
+ + G + K++E+ E L K + E+ER +RE+ ER +RLE+L
Sbjct: 313 KKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEEL 372
Query: 2539 RALEERSDWEGEGEEDHEGKKEKD 2562
A +R + E +E E KK+K+
Sbjct: 373 EA--KRKEEERLEQEKRERKKQKE 394
Score = 36.2 bits (82), Expect = 0.86
Identities = 30/111 (27%), Positives = 53/111 (47%), Gaps = 14/111 (12%)
Query: 2268 DYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGI-QQALR 2326
D+ AM + E+ +K + + H E +E + +EEE D +EEE+ +
Sbjct: 505 DWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDE 564
Query: 2327 ERKKREQERLAKEMQEKKLQQEL----------ERQKEE---DELKRRVKK 2364
E +K E+ + + +KK +E+ +R KEE D+ KRR++K
Sbjct: 565 EDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEERAYDKAKRRIEK 615
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapiens]
Length = 436
Score = 63.2 bits (152), Expect = 7e-09
Identities = 64/302 (21%), Positives = 143/302 (47%), Gaps = 21/302 (6%)
Query: 2272 MKAQEKAKKEQEE--RKHKGALEKEKERLQNMD---EEEYDALTEEEKLTFDRGIQQALR 2326
++ QE +EQE R+ +G + +++ +++ + E+ + E+E ++ Q +
Sbjct: 131 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 190
Query: 2327 ERKKREQERLAKEMQEKKLQQELERQKEEDEL----KRRVKKGKQGPIKEEPPMKKSQAA 2382
E + EQE E +E+ +QE + QK+E+++ ++ K+ +Q +EE K+ +
Sbjct: 191 EGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQV 250
Query: 2383 NKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEG 2442
KQ + K + +M E ++ +E+ M +++E +++ G+ +++QE+
Sbjct: 251 QKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQ----MREQEEQMR 306
Query: 2443 DNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGM---EEAPHEPDDQRQV 2499
+ + +Q + E K + + W++K+ + M EE E ++Q Q
Sbjct: 307 EQEEQMREQEEQMREQEEQMGKQEEQM---WEQKEQMWEQKEQMWKQEEQMGEQEEQMQK 363
Query: 2500 PLGGRRGRKDRERERLEKERTEKERLEREKAERERLEKLRALEERSDWEGEGEEDHEGKK 2559
+ RK E+ R ++E+ K+ + K E + E+ + E+ + E EE +K
Sbjct: 364 Q--EEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQK 421
Query: 2560 EK 2561
E+
Sbjct: 422 EQ 423
Score = 60.5 bits (145), Expect = 4e-08
Identities = 60/268 (22%), Positives = 126/268 (47%), Gaps = 29/268 (10%)
Query: 2265 MAQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQA 2324
M + M QE+ EQEE+ ++K++E+ M E+E +EE++ Q
Sbjct: 194 MGEQEGQMGEQEEQMGEQEEQ-----MQKQEEQ---MGEQEEQMRKQEEQMGEQEEQVQK 245
Query: 2325 LRERKKREQERLAKEMQEKKLQQELERQKEEDELKRR--VKKGKQGPIKEEPPMKKSQAA 2382
E+ ++++E++ K+ ++ + Q+E R++EE LK++ ++ +Q +EE ++ +
Sbjct: 246 QEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQM 305
Query: 2383 NKQVPPLTKVDVKMETIERKISVREQTM-SEKEELNKKKRNMGDVSMHGLPLVQDQEDSE 2441
+Q + + + +M E ++ +E+ M +KE++ ++K M QE+
Sbjct: 306 REQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQM-----------WKQEEQM 354
Query: 2442 GDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPL 2501
G+ + KQ K E K + + RKQ Q+ EE E +Q
Sbjct: 355 GEQEEQMQKQEEQVRKQEEQMRKQEEQM-----RKQEEQM--RKQEEQMGEQKEQMGEQK 407
Query: 2502 GGRRGRKDRERERLEKERTEKERLEREK 2529
R ++++ E+ E+ R ++E + +K
Sbjct: 408 EQMREQEEQMGEQKEQMRKQEEHMGEQK 435
Score = 58.5 bits (140), Expect = 2e-07
Identities = 66/305 (21%), Positives = 147/305 (48%), Gaps = 38/305 (12%)
Query: 2272 MKAQEKAKKEQEE--RKHKGALEKEKERLQNMD---EEEYDALTEEEKLTFDRGIQQALR 2326
++ QE +EQE R+ +G + +++ +++ + E+ + E+E ++ Q +
Sbjct: 54 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 113
Query: 2327 ERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQ--AANK 2384
E + REQE +E + + +QE + +++E +++ ++G ++E+ + Q +
Sbjct: 114 EGQVREQEGQVREQEGQVREQEGQVREQEGQVRE-----QEGQVREQEGQVREQEGQVRE 168
Query: 2385 QVPPLTKVDVKMETIERKISVREQTMSEKE-ELNKKKRNMGDVSMHGLPLVQDQEDSEGD 2443
Q + + + ++ E ++ +E M E+E ++ +++ MG+ +Q QE+ G+
Sbjct: 169 QEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQ----MQKQEEQMGE 224
Query: 2444 NSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGG 2503
+ KQ + E K + + +KQ Q+ EE E ++Q
Sbjct: 225 QEEQMRKQEEQMGEQEEQVQKQEEQV-----QKQEEQM--RKQEEQMREQEEQM------ 271
Query: 2504 RRGRKDRERERLEKERTEKERL--EREKAERERLEKLRALEERSDWEGE---GEEDHEGK 2558
R+ E+ +KE+TE+E E+E+ RE+ E++R EE+ + E +E+ GK
Sbjct: 272 ---REQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGK 328
Query: 2559 KEKDL 2563
+E+ +
Sbjct: 329 QEEQM 333
Score = 56.6 bits (135), Expect = 6e-07
Identities = 55/278 (19%), Positives = 134/278 (48%), Gaps = 27/278 (9%)
Query: 2272 MKAQEKAKKEQEE--RKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERK 2329
++ QE +EQE R+ +G + +++ ++ +E+ + E+E+ + Q +E +
Sbjct: 173 VREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQ----MGEQEEQMQKQEEQMGEQEEQ 228
Query: 2330 KREQERLAKEMQEKKLQQELERQKEEDELKRR---VKKGKQGPIKEEPPMKKSQAANKQV 2386
R+QE E +E+ +QE + QK+E++++++ +++ ++ ++E M K + +Q
Sbjct: 229 MRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQE 288
Query: 2387 PPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSK 2446
+ + +M E ++ +E+ M E+EE +++QE+ G +
Sbjct: 289 EQTGEQEEQMREQEEQMREQEEQMREQEE-----------------QMREQEEQMGKQEE 331
Query: 2447 DPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRG 2506
+Q ++ E K + + ++ Q + EE + ++Q + R
Sbjct: 332 QMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRK 391
Query: 2507 RKDRERERLEKERTEKERL-EREKAERERLEKLRALEE 2543
++++ E+ E+ +KE++ E+E+ E+ E++R EE
Sbjct: 392 QEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEE 429
Score = 49.7 bits (117), Expect = 8e-05
Identities = 57/292 (19%), Positives = 132/292 (45%), Gaps = 27/292 (9%)
Query: 2280 KEQEERKHKGALEKEKERLQNMD---EEEYDALTEEEKLTFDRGIQQALRERKKREQERL 2336
+E + R+ +G + +++ +++ + E+ + E+E ++ Q +E + REQE
Sbjct: 50 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 109
Query: 2337 AKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKVDVKM 2396
+E + + +QE + +++E +++ + +G ++E+ + Q + + +
Sbjct: 110 VREQEGQVREQEGQVREQEGQVREQ-----EGQVREQEGQVREQEGQVREQEGQVREQEG 164
Query: 2397 ETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQLAPKF 2456
+ E++ VREQ +E+ + + G + +QE G+ + +Q
Sbjct: 165 QVREQEGQVREQEGQVREQEGQVREQEGQMG--------EQEGQMGEQEEQMGEQEEQMQ 216
Query: 2457 KTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRERERLE 2516
K E + + + RKQ Q+ + E Q+Q ++ + RE+E
Sbjct: 217 KQEEQMGEQEEQM-----RKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQM 271
Query: 2517 KERTE-----KERLEREKAERERLEKLRALEER-SDWEGEGEEDHEGKKEKD 2562
+E+ E KE+ E+E+ E+ E++R EE+ + E + E E +E++
Sbjct: 272 REQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQE 323
Score = 48.9 bits (115), Expect = 1e-04
Identities = 66/331 (19%), Positives = 141/331 (42%), Gaps = 24/331 (7%)
Query: 2275 QEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKREQE 2334
+E +K E ++ +E EK +Q + +E E +K+ + Q +E + REQE
Sbjct: 7 EELKEKNAELQEELQLVETEKSEIQ-LHIKELKRKLETDKIPLPQEGQVREQEGQVREQE 65
Query: 2335 RLAKEMQEKKLQQ-----ELERQKEEDELKRRVKKG----KQGPIKEEPPMKKSQAANKQ 2385
+E + + +Q E E Q E E + R ++G ++G ++E+ + Q +
Sbjct: 66 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 125
Query: 2386 VPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPL------------ 2433
+ + + E++ VREQ +E+ + + G V +
Sbjct: 126 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 185
Query: 2434 -VQDQEDSEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHE 2492
V++QE G+ +Q + E K + + ++ + + EE +
Sbjct: 186 QVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQK 245
Query: 2493 PDDQRQVPLGGRRGRKDRERERLEKERTEKERLEREKAERERLEKLRALEER-SDWEGEG 2551
++Q Q R ++++ RE+ E+ R ++E++ ++K + E+ E+ EE+ + E +
Sbjct: 246 QEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQM 305
Query: 2552 EEDHEGKKEKDLGVPFLDIQTPDFEGLSWKQ 2582
E E +E++ + + Q E W+Q
Sbjct: 306 REQEEQMREQEEQMREQEEQMGKQEEQMWEQ 336
Score = 48.1 bits (113), Expect = 2e-04
Identities = 30/144 (20%), Positives = 85/144 (59%), Gaps = 5/144 (3%)
Query: 2272 MKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKR 2331
M+ QE+ +EQEE+ + E+ +E+ + M ++E + + E+++ +++ Q +E +
Sbjct: 298 MREQEEQMREQEEQMREQE-EQMREQEEQMGKQE-EQMWEQKEQMWEQKEQMWKQEEQMG 355
Query: 2332 EQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTK 2391
EQE ++ +E+ +QE + +K+E++++++ ++ ++ +EE ++ + +Q + +
Sbjct: 356 EQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRK---QEEQMGEQKEQMGEQKEQMRE 412
Query: 2392 VDVKMETIERKISVREQTMSEKEE 2415
+ +M + ++ +E+ M E++E
Sbjct: 413 QEEQMGEQKEQMRKQEEHMGEQKE 436
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A member
6-like protein 6 [Homo sapiens]
Length = 655
Score = 63.2 bits (152), Expect = 7e-09
Identities = 74/312 (23%), Positives = 142/312 (45%), Gaps = 29/312 (9%)
Query: 2283 EERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKREQERLAKEMQE 2342
EE K K A +EK RL ++ E ++ K +R +++ + E +RL KE+Q
Sbjct: 214 EELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQ- 272
Query: 2343 KKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKVDVKMETIERK 2402
+ +L+ Q EE+EL + + +EE ++ + +Q + + ++K+ E K
Sbjct: 273 -SVSAKLQAQVEENELWNLLNQQ-----QEEKMWRQEEKIQEQEEKMCEQELKIREQEEK 326
Query: 2403 ISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQLAPKFKTYELT 2462
+ +E+ M E+EE K R D +++QE+ + +K + K E
Sbjct: 327 MWRQEEKMHEQEE---KIREQEDKMWRQEEKIREQEEKIREQE---EKMWRQEEKIREQD 380
Query: 2463 LKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRERERLEKERTEK 2522
K + W +++ ++ +E + RQ + K RE+E E R E+
Sbjct: 381 EKIQEQEEEMWRQEEKIR-----EQEEKRQEKMWRQEKKMREQDEKIREQEE-EMWRQEE 434
Query: 2523 ERLEREKAERERLEKLRALEERSDWEGEGEEDHEGKKEKDLGVPFLDIQTPDFEGLSWKQ 2582
+ E E+ +++ EKLR +EE+ E E ++ E K ++ + + + E +W+Q
Sbjct: 435 KIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQ------EEKIQEQEEKTWRQ 488
Query: 2583 ALESDKLPKGEQ 2594
+KL K E+
Sbjct: 489 ----EKLLKQEE 496
Score = 61.2 bits (147), Expect = 2e-08
Identities = 78/332 (23%), Positives = 155/332 (46%), Gaps = 28/332 (8%)
Query: 2262 ILNMAQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGI 2321
+LN Q+ + +EK + EQEE+ + L K +E+ + M +E +EEK+ ++
Sbjct: 290 LLNQQQEEKMWRQEEKIQ-EQEEKMCEQEL-KIREQEEKMWRQEEKMHEQEEKIR-EQED 346
Query: 2322 QQALRERKKREQERLAKEMQEKKLQQELE--------RQKEEDELKRRVKKGKQGPIKEE 2373
+ +E K REQE +E +EK +QE + +++EE+ ++ K +Q ++E
Sbjct: 347 KMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQE 406
Query: 2374 PPMKKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPL 2433
++ + +Q + + + +M E KI E+ M ++EE K R + +
Sbjct: 407 KMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEE---KLREVEEKMQEEEEK 463
Query: 2434 VQDQEDSEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGM---EEAP 2490
+Q+QE+ + ++ ++ K E LK + I W++++ + M EE
Sbjct: 464 MQEQEE-KIQRQEEKIQEQEEKTWRQEKLLKQEEKI---WEQEEKMWRQEEKMWEQEEKM 519
Query: 2491 HEPDDQRQVPLGGRRGRKDRERERLEKERTEKERLEREKAERERLEKLRALEERSDWEGE 2550
E +++ Q R+ K RE+E + + E++ E+E +E E+L L ++++ G
Sbjct: 520 QEQEEKMQ-----RQEEKMREQE-VRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLG- 572
Query: 2551 GEEDHEGKKEKDLGVPFLDIQTPDFEGLSWKQ 2582
G G + P L ++ E S +Q
Sbjct: 573 GAGRESGSQRLPTLTPILQVELKSQEAQSLQQ 604
Score = 57.4 bits (137), Expect = 4e-07
Identities = 55/283 (19%), Positives = 135/283 (47%), Gaps = 4/283 (1%)
Query: 2263 LNMAQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQ 2322
L + Q ++A K+ Q A +E E +++++ + + +E+ ++ +
Sbjct: 253 LLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEK 312
Query: 2323 QALRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAA 2382
+E K REQE +EK +QE + +++ED++ R+ +K ++ +EE ++ +
Sbjct: 313 MCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIRE---QEEKIREQEEKM 369
Query: 2383 NKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEG 2442
+Q + + D K++ E ++ +E+ + E+EE ++K + M +++ E
Sbjct: 370 WRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEM 429
Query: 2443 DNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLG 2502
++ ++L + E L++V+ + + K Q +E + +++
Sbjct: 430 WRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQE 489
Query: 2503 GRRGRKDRERERLEKE-RTEKERLEREKAERERLEKLRALEER 2544
++++ E+ EK R E++ E+E+ +E+ EK++ EE+
Sbjct: 490 KLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEK 532
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A member
6-like protein 6 [Homo sapiens]
Length = 655
Score = 63.2 bits (152), Expect = 7e-09
Identities = 74/312 (23%), Positives = 142/312 (45%), Gaps = 29/312 (9%)
Query: 2283 EERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKREQERLAKEMQE 2342
EE K K A +EK RL ++ E ++ K +R +++ + E +RL KE+Q
Sbjct: 214 EELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQ- 272
Query: 2343 KKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKVDVKMETIERK 2402
+ +L+ Q EE+EL + + +EE ++ + +Q + + ++K+ E K
Sbjct: 273 -SVSAKLQAQVEENELWNLLNQQ-----QEEKMWRQEEKIQEQEEKMCEQELKIREQEEK 326
Query: 2403 ISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQLAPKFKTYELT 2462
+ +E+ M E+EE K R D +++QE+ + +K + K E
Sbjct: 327 MWRQEEKMHEQEE---KIREQEDKMWRQEEKIREQEEKIREQE---EKMWRQEEKIREQD 380
Query: 2463 LKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRERERLEKERTEK 2522
K + W +++ ++ +E + RQ + K RE+E E R E+
Sbjct: 381 EKIQEQEEEMWRQEEKIR-----EQEEKRQEKMWRQEKKMREQDEKIREQEE-EMWRQEE 434
Query: 2523 ERLEREKAERERLEKLRALEERSDWEGEGEEDHEGKKEKDLGVPFLDIQTPDFEGLSWKQ 2582
+ E E+ +++ EKLR +EE+ E E ++ E K ++ + + + E +W+Q
Sbjct: 435 KIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQ------EEKIQEQEEKTWRQ 488
Query: 2583 ALESDKLPKGEQ 2594
+KL K E+
Sbjct: 489 ----EKLLKQEE 496
Score = 61.2 bits (147), Expect = 2e-08
Identities = 78/332 (23%), Positives = 155/332 (46%), Gaps = 28/332 (8%)
Query: 2262 ILNMAQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGI 2321
+LN Q+ + +EK + EQEE+ + L K +E+ + M +E +EEK+ ++
Sbjct: 290 LLNQQQEEKMWRQEEKIQ-EQEEKMCEQEL-KIREQEEKMWRQEEKMHEQEEKIR-EQED 346
Query: 2322 QQALRERKKREQERLAKEMQEKKLQQELE--------RQKEEDELKRRVKKGKQGPIKEE 2373
+ +E K REQE +E +EK +QE + +++EE+ ++ K +Q ++E
Sbjct: 347 KMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQE 406
Query: 2374 PPMKKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPL 2433
++ + +Q + + + +M E KI E+ M ++EE K R + +
Sbjct: 407 KMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEE---KLREVEEKMQEEEEK 463
Query: 2434 VQDQEDSEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGM---EEAP 2490
+Q+QE+ + ++ ++ K E LK + I W++++ + M EE
Sbjct: 464 MQEQEE-KIQRQEEKIQEQEEKTWRQEKLLKQEEKI---WEQEEKMWRQEEKMWEQEEKM 519
Query: 2491 HEPDDQRQVPLGGRRGRKDRERERLEKERTEKERLEREKAERERLEKLRALEERSDWEGE 2550
E +++ Q R+ K RE+E + + E++ E+E +E E+L L ++++ G
Sbjct: 520 QEQEEKMQ-----RQEEKMREQE-VRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLG- 572
Query: 2551 GEEDHEGKKEKDLGVPFLDIQTPDFEGLSWKQ 2582
G G + P L ++ E S +Q
Sbjct: 573 GAGRESGSQRLPTLTPILQVELKSQEAQSLQQ 604
Score = 57.4 bits (137), Expect = 4e-07
Identities = 55/283 (19%), Positives = 135/283 (47%), Gaps = 4/283 (1%)
Query: 2263 LNMAQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQ 2322
L + Q ++A K+ Q A +E E +++++ + + +E+ ++ +
Sbjct: 253 LLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEK 312
Query: 2323 QALRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAA 2382
+E K REQE +EK +QE + +++ED++ R+ +K ++ +EE ++ +
Sbjct: 313 MCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIRE---QEEKIREQEEKM 369
Query: 2383 NKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEG 2442
+Q + + D K++ E ++ +E+ + E+EE ++K + M +++ E
Sbjct: 370 WRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEM 429
Query: 2443 DNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLG 2502
++ ++L + E L++V+ + + K Q +E + +++
Sbjct: 430 WRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQE 489
Query: 2503 GRRGRKDRERERLEKE-RTEKERLEREKAERERLEKLRALEER 2544
++++ E+ EK R E++ E+E+ +E+ EK++ EE+
Sbjct: 490 KLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEK 532
>gi|22758136 MAP7 domain containing 2 [Homo sapiens]
Length = 732
Score = 62.4 bits (150), Expect = 1e-08
Identities = 51/160 (31%), Positives = 81/160 (50%), Gaps = 21/160 (13%)
Query: 2266 AQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQAL 2325
A+ A + Q + +KEQEE++ EKE ++ EE EEE+L + ++
Sbjct: 401 AKILAEKRRQARLQKEQEEQERV-----EKEEQDRLEREELKRKAEEERLRLEEEARKQE 455
Query: 2326 RERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPM--KKSQAAN 2383
ERK++E+E+ +E +EK+ E ++K E+EL + K KQ K+E M K+ +AA
Sbjct: 456 EERKRQEEEKKKQEGEEKRKAGEEAKRKAEEEL---LLKEKQEQEKQEKAMIEKQKEAAE 512
Query: 2384 KQVPPLTKVDVKMETIERKISVREQTM--SEKEELNKKKR 2421
+ E E+ REQ M E+E L +KKR
Sbjct: 513 TKA---------REVAEQMRLEREQIMLQIEQERLERKKR 543
Score = 42.7 bits (99), Expect = 0.009
Identities = 38/128 (29%), Positives = 63/128 (49%), Gaps = 21/128 (16%)
Query: 2273 KAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKRE 2332
KA E+AK++ EE L KEK+ E++ A+ E++K + + R+ E
Sbjct: 475 KAGEEAKRKAEEE----LLLKEKQEQ----EKQEKAMIEKQKEAAE------TKAREVAE 520
Query: 2333 QERLAKEMQEKKLQQE-LERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTK 2391
Q RL +E +++QE LER+K DE+ +R +K + PP K + V P
Sbjct: 521 QMRLEREQIMLQIEQERLERKKRIDEIMKRTRK------SDVPPQVKKEDPKVGVQPAVC 574
Query: 2392 VDVKMETI 2399
V+ K + +
Sbjct: 575 VEKKTKLV 582
Score = 42.0 bits (97), Expect = 0.016
Identities = 55/277 (19%), Positives = 115/277 (41%), Gaps = 67/277 (24%)
Query: 2275 QEKAKKEQEERKHKGALEKEKERLQN---MDEEEYDALTEEEKLTFDRGIQQALRERKK- 2330
+ KA+KE+ ++ +G L ++ Q +++ D E+ G + K
Sbjct: 331 KRKAEKEKSNKEREGTLAQQAAGPQGEEALEKHVVDKHASEKHAAAAGGKAENSAALGKP 390
Query: 2331 ----REQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQV 2386
+ AK + EK+ Q L++++EE E RV+K +Q ++ E +K++
Sbjct: 391 TAGTTDAGEAAKILAEKRRQARLQKEQEEQE---RVEKEEQDRLEREELKRKAE------ 441
Query: 2387 PPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSK 2446
E ++ + E+ ++EE +++ ++++ EG+ +
Sbjct: 442 -------------EERLRLEEEARKQEEERKRQE--------------EEKKKQEGEEKR 474
Query: 2447 DPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRG 2506
++ K + EL LK+ Q +E + ++Q +
Sbjct: 475 KAGEEAKRKAEE-ELLLKEKQE------------------QEKQEKAMIEKQKEAAETKA 515
Query: 2507 RKDRERERLEKE----RTEKERLEREKAERERLEKLR 2539
R+ E+ RLE+E + E+ERLER+K E +++ R
Sbjct: 516 REVAEQMRLEREQIMLQIEQERLERKKRIDEIMKRTR 552
Score = 40.4 bits (93), Expect = 0.046
Identities = 31/90 (34%), Positives = 47/90 (52%), Gaps = 9/90 (10%)
Query: 2482 PPAGMEEAPHEPDDQRQVPLGGRRGRKDRERERLEKERTEKERLERE----KAERERL-- 2535
P AG +A + R ++ E+ER+EKE E++RLERE KAE ERL
Sbjct: 390 PTAGTTDAGEAAKILAEKRRQARLQKEQEEQERVEKE--EQDRLEREELKRKAEEERLRL 447
Query: 2536 -EKLRALEERSDWEGEGEEDHEGKKEKDLG 2564
E+ R EE + E ++ EG++++ G
Sbjct: 448 EEEARKQEEERKRQEEEKKKQEGEEKRKAG 477
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 61.6 bits (148), Expect = 2e-08
Identities = 62/296 (20%), Positives = 134/296 (45%), Gaps = 28/296 (9%)
Query: 2273 KAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKRE 2332
+ +EK K+ + ER+ ++ KER ++ D E D + E+ + DR ++ K R+
Sbjct: 333 REREKEKERERERERDRDRDRTKERDRDRDRER-DRDRDRERSS-DRNKDRSRSREKSRD 390
Query: 2333 QERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKV 2392
+ER + +E++ ++E ER++E + + R ++ ++ K+ + + A ++ K+
Sbjct: 391 REREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKL 450
Query: 2393 DVKMETIERKIS---VREQTMS-----EKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDN 2444
K + ++ +RE+ + E E +++R M + ++D +D D
Sbjct: 451 REKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDD- 509
Query: 2445 SKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGR 2504
PK+ K ++ DR++ ++ + E ++ RQ L
Sbjct: 510 ---------PKYYRGSALQKRLR------DREKEMEADERDRKREKEELEEIRQRLLAEG 554
Query: 2505 RGRKDRERERLEK--ERTEKERLEREKAERERLEKLRALEERSDWEGEGEEDHEGK 2558
D E +R+E+ ER + ++++E E E+ + EE+ + E EE+ E K
Sbjct: 555 HPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQK 610
Score = 58.5 bits (140), Expect = 2e-07
Identities = 77/366 (21%), Positives = 153/366 (41%), Gaps = 64/366 (17%)
Query: 2256 SREHIYILNMAQDYAAMKAQEKAK-----KEQEERKHKGALEKEKERLQNMDEEEYDALT 2310
++E I + M +D + ++E +K K+ EE K K KEKER Q +++E +
Sbjct: 260 TKEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGK----KEKER-QEIEKERRERER 314
Query: 2311 EEEKLTFDRGIQQALRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPI 2370
E E RER++RE+ER + +E++ ++E ER++E D + R K+ +
Sbjct: 315 ERE------------RERERREREREREREREREKEKERERERERDRDRDRTKERDRDRD 362
Query: 2371 KEEPPMKKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHG 2430
+E + + ++ + ++ K ER+ + E+E +++R
Sbjct: 363 RERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERERERERE 422
Query: 2431 LPLVQDQEDSEGDNSKDP------DKQLAPKFKTYELTLKDVQ------------NILMY 2472
+D++ ++ +D +++L K Y+ LK+ +
Sbjct: 423 REREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAERE 482
Query: 2473 WDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGR-----RGRKDRERERLEKERTEKERLER 2527
+R++ + ++E + DD R P R + +DRE+E ER K E
Sbjct: 483 EERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEE 542
Query: 2528 EKAERERL-------------------EKLRALEERSDWEGEGEEDHEGKKEKDLGVPFL 2568
+ R+RL E+ R + + + E E EE+ + +KE+ P
Sbjct: 543 LEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPME 602
Query: 2569 DIQTPD 2574
+ + P+
Sbjct: 603 EEEEPE 608
Score = 53.5 bits (127), Expect = 5e-06
Identities = 47/189 (24%), Positives = 88/189 (46%), Gaps = 17/189 (8%)
Query: 2378 KSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEEL----NKKKRNMGDVSMHGLPL 2433
K +A+N P T + E ++ + R+Q + E+ + N P
Sbjct: 175 KKKASNGNARPETVTNDDEEALDEETKRRDQMIKGAIEVLIREYSSELNAPSQESDSHPR 234
Query: 2434 VQDQEDSEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEP 2493
+ +E E + P +AP +T +D+ I M D++ + + + +
Sbjct: 235 KKKKEKKEDIFRRFP---VAPLIPYPLITKEDINAIEMEEDKRDLISREISKFRDTHKKL 291
Query: 2494 DDQRQVPLGGRRGRKDRERERLEKERTEKERLEREKAERERLEKLRALEERSDWEGEGEE 2553
++++ G+K++ER+ +EKER E+ER ERE+ ERER E+ R E + E E E
Sbjct: 292 EEEK--------GKKEKERQEIEKERRERER-ERER-ERERREREREREREREREKEKER 341
Query: 2554 DHEGKKEKD 2562
+ E ++++D
Sbjct: 342 ERERERDRD 350
Score = 52.4 bits (124), Expect = 1e-05
Identities = 63/310 (20%), Positives = 129/310 (41%), Gaps = 21/310 (6%)
Query: 2260 IYILNMAQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDR 2319
++ L + + +K K K + +E K K R + + ++ +AL EE K D+
Sbjct: 147 LHDLQIGEKKLLVKVDAKTKAQLDEWKAKKKASNGNARPETVTNDDEEALDEETKRR-DQ 205
Query: 2320 GIQQALRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKS 2379
I+ A+ + L QE +++++++++ RR P+ P + K
Sbjct: 206 MIKGAIEVLIREYSSELNAPSQESDSHPRKKKKEKKEDIFRRFPVA---PLIPYPLITK- 261
Query: 2380 QAANKQVPPLTKVDVKMETIERKISVREQTMSE-KEELNKKKRNMGDVSMHGLPLVQDQE 2438
+ + + + K + I R+IS T + +EE KK++ ++ +++E
Sbjct: 262 ----EDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERE 317
Query: 2439 DSEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQ 2498
++ +++ + + + ++ + DR + + E + D +R
Sbjct: 318 RERERREREREREREREREKEKERERERERDR---DRDRTKERDRDRDRERDRDRDRERS 374
Query: 2499 VPLGGRRGR-------KDRERERLEKERTEKERLEREKAERERLEKLRALEERSDWEGEG 2551
R R ++RERER + E+ER + ERER E+ R E D + +
Sbjct: 375 SDRNKDRSRSREKSRDRERERERERERERERERERERERERER-EREREREREKDKKRDR 433
Query: 2552 EEDHEGKKEK 2561
EED E E+
Sbjct: 434 EEDEEDAYER 443
Score = 51.2 bits (121), Expect = 3e-05
Identities = 56/300 (18%), Positives = 131/300 (43%), Gaps = 57/300 (19%)
Query: 2273 KAQEKAKKEQEERKHKGA-------LEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQAL 2325
+ ++K KKE R+ A + KE M+E++ D ++ E ++ R + L
Sbjct: 234 RKKKKEKKEDIFRRFPVAPLIPYPLITKEDINAIEMEEDKRDLISRE--ISKFRDTHKKL 291
Query: 2326 RE---RKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAA 2382
E +K++E++ + KE +E++ ++E ER++ E E +R ++ ++ + E ++ +
Sbjct: 292 EEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRDR 351
Query: 2383 NKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEG 2442
++ TK + ER R++ + NK + + S + + + E
Sbjct: 352 DR-----TKERDRDRDRERD---RDRDRERSSDRNKDRSRSREKSRDRERERERERERER 403
Query: 2443 DNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLG 2502
+ ++ +++ E E + +R+
Sbjct: 404 ERERERERE-----------------------------------REREREREREREREKD 428
Query: 2503 GRRGRKDRERERLEKERTEKERLEREKAERERLE--KLRALEERSDWEGEGEEDHEGKKE 2560
+R R++ E + E+ + E++ E+E A +ERL+ ++R ++ ++E E E + E ++E
Sbjct: 429 KKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRRE 488
Score = 42.0 bits (97), Expect = 0.016
Identities = 33/152 (21%), Positives = 73/152 (48%), Gaps = 35/152 (23%)
Query: 2273 KAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKK-- 2330
K +E K+ + E + + + KE +RL+ E+YD ++ K +Q+ LR+R+K
Sbjct: 471 KTREYEKEAEREEERRREMAKEAKRLKEF-LEDYDDDRDDPKYYRGSALQKRLRDREKEM 529
Query: 2331 ----REQERLAKEMQE-----------------KKLQQELERQK-----------EEDEL 2358
R+++R +E++E ++++QE ER++ EE+E
Sbjct: 530 EADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEE 589
Query: 2359 KRRVKKGKQGPIKEEPPMKKSQAANKQVPPLT 2390
K+ ++ ++ P++EE ++ + P++
Sbjct: 590 KQEKEEKREEPMEEEEEPEQKPCLKPTLRPIS 621
Score = 37.4 bits (85), Expect = 0.39
Identities = 27/115 (23%), Positives = 56/115 (48%), Gaps = 4/115 (3%)
Query: 2273 KAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKRE 2332
+ +E E++ ++ K LE+ ++RL + DA + + +R Q +++ + E
Sbjct: 525 REKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESE 584
Query: 2333 QERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVP 2387
+E +E QEK+ ++E ++EE+ ++ K PI P + S A+ P
Sbjct: 585 EEE--EEKQEKEEKREEPMEEEEEPEQKPCLKPTLRPISSAPSV--SSASGNATP 635
>gi|83035129 coiled-coil domain containing 108 isoform 1 [Homo
sapiens]
Length = 1925
Score = 60.8 bits (146), Expect = 3e-08
Identities = 53/242 (21%), Positives = 99/242 (40%), Gaps = 19/242 (7%)
Query: 120 LILRNNDKIPRLVKVVEESSPYFKVISPKDIGHKVAPGVPSIFRILFTPEENKDYAHTLT 179
L+L+N + +K + +F + P+ I ++PG+ I+F P E K+Y L
Sbjct: 166 LVLKNRSLKLQKMKYRPPKTKFFFTVIPQPIF--LSPGITLTLPIVFRPLEAKEYMDQLW 223
Query: 180 CVTEREKFIVPIKAR-GARAILDFPDKLNFSTCPVKYSTQKILLVRNIGNKNAVFHIKTC 238
F V ++A ++ P L C V +T+ + N+G+ F +
Sbjct: 224 FEKAEGMFCVGLRATLPCHRLICRPPSLQLPMCAVGDTTEAFFCLDNVGDLPTFFTWEFS 283
Query: 239 RPFSIEPAIGTLNVGESMQLEVEFEPQSVGDHSGRLIVCYDTGEKVFVSLYGAAI----- 293
PF + PA G L G++ Q++V F+P + + + Y G + S+ A+
Sbjct: 284 SPFQMLPATGLLEPGQASQIKVTFQPLTAVIYEVQATCWYGAGSRQRSSIQLQAVAKCAQ 343
Query: 294 -----------DMNIRLDKNSLTIEKTYISLANQRTITIHNRSNIIAHFLWKVFATQQEE 342
D + + L + ++R I +HN S + A F ++ + E
Sbjct: 344 LLVSIKHKCPEDQDAEGFQKLLYFGSVAVGCTSERQIRLHNPSAVNAPFRIEISPDELAE 403
Query: 343 DR 344
D+
Sbjct: 404 DQ 405
Score = 57.8 bits (138), Expect = 3e-07
Identities = 59/276 (21%), Positives = 111/276 (40%), Gaps = 25/276 (9%)
Query: 4366 VVKPGNTLEIPITFYPRESINY--QELIPFEINGLSQQTVEIKGKGTKMKILV------- 4416
+++PG +I +TF P ++ Y Q + + +++++ ++LV
Sbjct: 294 LLEPGQASQIKVTFQPLTAVIYEVQATCWYGAGSRQRSSIQLQAVAKCAQLLVSIKHKCP 353
Query: 4417 ----LDPANRIVKLGAVLPGQVVKRTVSIMNNSLAQLTFNQSILFTIPELQEPKVLTLAP 4472
+ +++ G+V G +R + + N S F I + EL E + +
Sbjct: 354 EDQDAEGFQKLLYFGSVAVGCTSERQIRLHNPSAVNAPFRIEI--SPDELAEDQAFSCPT 411
Query: 4473 FHNITLKPKEVCKLEVIFAPKK---RVPPFSEEVFMECMGLLRPLFLLSGCCQALEISLD 4529
H I L ++ C + V F PK R + + C + L + G C+ +SL
Sbjct: 412 AHGIVLPGEKKC-VSVFFHPKTLDTRTVDYCSIMPSGCAS--KTLLKVVGFCRGPAVSLQ 468
Query: 4530 QEHIPFGPVVYQTQATRRILMMNTGDVGARFKWDIKKFEPHFSISPEEGYITSGMEVSFE 4589
+ F V ++ + + + N D A F++ I E F+I P G + ++
Sbjct: 469 HYCVNFSWVNLGERSEQPLWIENQSDCTAHFQFAIDCLESVFTIRPAFGTLVGKARMTLH 528
Query: 4590 VTYHPTEVGKESLC-KNILCYIQGGSPLSLTLSGVC 4624
+ PT +C + + C I PL L L G C
Sbjct: 529 CAFQPTH---PIICFRRVACLIHHQDPLFLDLMGTC 561
Score = 48.9 bits (115), Expect = 1e-04
Identities = 56/234 (23%), Positives = 98/234 (41%), Gaps = 19/234 (8%)
Query: 3888 PFSVEPSSGIVPVGKIQKFKVKFSPLDIGDFESNLFCQIPNLPPGEQGPVLVAKGRSTLP 3947
PF + P++G++ G+ + KV F PL +E C ++ RS++
Sbjct: 285 PFQMLPATGLLEPGQASQIKVTFQPLTAVIYEVQATCWYG----------AGSRQRSSIQ 334
Query: 3948 ICHFDLKDSDYISGHQRNPELRGSSGGALDPNTRVIEFTTVGIGGKNLRTFTILNPTNST 4007
+ +S + PE + + G +++ F +V +G + R + NP+
Sbjct: 335 LQAVAKCAQLLVSIKHKCPEDQDAEGFQ-----KLLYFGSVAVGCTSERQIRLHNPSAVN 389
Query: 4008 YSFCWISEEIESLQNPAAFTCLTEKGFIHP-EKKAEIVFQFTPFHLGITESSWTFLIPEH 4066
F I + L AF+C T G + P EKK VF F P L + ++P
Sbjct: 390 APFR-IEISPDELAEDQAFSCPTAHGIVLPGEKKCVSVF-FHPKTLDTRTVDYCSIMPSG 447
Query: 4067 NITVPFL-LVGKTTEPLISLNKSHLNFSSLLIGREARETVQIINKEEQGFDFSF 4119
+ L +VG P +SL +NFS + +G + + + I N+ + F F
Sbjct: 448 CASKTLLKVVGFCRGPAVSLQHYCVNFSWVNLGERSEQPLWIENQSDCTAHFQF 501
Score = 39.7 bits (91), Expect = 0.078
Identities = 40/169 (23%), Positives = 73/169 (43%), Gaps = 20/169 (11%)
Query: 4256 SPIDSTVDVGQSVHATLSFQPLKKCVLTD-LELIIKISHGPTFMCNISGCAVSPA---IH 4311
SP ++ GQ L + L + TD L ++ K+SHG + N G V P +H
Sbjct: 1241 SPKAGSLSPGQEQMVELKYSHL--FIGTDHLPVLFKVSHGREILLNFIGVTVKPEQKYVH 1298
Query: 4312 FSFTSYNFGTCFIYQAGMPPYKQTLVITNKEETPMSIDCLYTNTTHLE-----------V 4360
F+ T++ F I +PP +Q + N P++ + + ++ +
Sbjct: 1299 FTSTTHQFIPIPIGDT-LPP-RQIYELYNGGSVPVTYEVQTDVLSQVQEKNFDHPIFCCL 1356
Query: 4361 NSRVDVVKPGNTLEIPITFYPRESINYQELIPFEINGLSQQTVEIKGKG 4409
N + ++ +PG+T + F P E+ Y +P I G + + +G G
Sbjct: 1357 NPKGEI-QPGSTARVLWIFSPIEAKTYTVDVPIHILGWNSALIHFQGVG 1404
Score = 39.3 bits (90), Expect = 0.10
Identities = 32/130 (24%), Positives = 59/130 (45%), Gaps = 20/130 (15%)
Query: 2252 KAIGSREHIYILNMAQDYAAMKAQEKAKKEQEER-KHKGALEKEKERLQNMDEEEYDALT 2310
K + + +Y++ + ++ K K+ +E+R +H L K++E + EEE + L
Sbjct: 1717 KFMDQKNSLYLMPILPVPSSSWEDGKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELE 1776
Query: 2311 EEEKLTFDRGIQQALRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPI 2370
EEE+ E ++ E+E L KE E E+++E DE + +V GP
Sbjct: 1777 EEEE------------EEEETEEEELGKEEIE-------EKEEERDEKEEKVSWAGIGPT 1817
Query: 2371 KEEPPMKKSQ 2380
+ + Q
Sbjct: 1818 PQPESQESMQ 1827
Score = 36.6 bits (83), Expect = 0.66
Identities = 33/149 (22%), Positives = 64/149 (42%), Gaps = 21/149 (14%)
Query: 1329 FDILPLFGVLQPHSSHQISFTFYGHANIIAQAKALCEVEEGPTYEITLKGEA-------- 1380
F +LP G+L+P + QI TF +I + +A C G +++ +A
Sbjct: 286 FQMLPATGLLEPGQASQIKVTFQPLTAVIYEVQATCWYGAGSRQRSSIQLQAVAKCAQLL 345
Query: 1381 -SLVNYSFDTKD-------IHYGLQLFDHVTEREITLTNMGKVGFEFKVLTDHQSSPDNL 1432
S+ + + +D +++G +ER+I L N V F++ + SPD L
Sbjct: 346 VSIKHKCPEDQDAEGFQKLLYFGSVAVGCTSERQIRLHNPSAVNAPFRI----EISPDEL 401
Query: 1433 LPGVPLILPVS-GFISSHQEQVLKVYYLP 1460
P + G + +++ + V++ P
Sbjct: 402 AEDQAFSCPTAHGIVLPGEKKCVSVFFHP 430
Score = 35.4 bits (80), Expect = 1.5
Identities = 42/199 (21%), Positives = 78/199 (39%), Gaps = 18/199 (9%)
Query: 400 FNNVFTVEPLEGDVWPNSSAEITVYFNPLEAKLYQ--------------QTIYCDILGRE 445
F++ F + P G + P +++I V F PL A +Y+ +I + +
Sbjct: 282 FSSPFQMLPATGLLEPGQASQIKVTFQPLTAVIYEVQATCWYGAGSRQRSSIQLQAVAKC 341
Query: 446 IRLPLRIKGEGMGPKIHFNFE-LLDIGKVFTGSAHCYEAILYNKGSIDALF--NMTPPTS 502
+L + IK + + F+ LL G V G + L+N +++A F ++P
Sbjct: 342 AQLLVSIKHKCPEDQDAEGFQKLLYFGSVAVGCTSERQIRLHNPSAVNAPFRIEISPDEL 401
Query: 503 ALGACFVFSPKEGIIEPSGVQAIQISFSSTILGNFEEEFL-VNVNGSPEPVKLTIRGCVI 561
A F GI+ P + + + F L ++ + +G L + G
Sbjct: 402 AEDQAFSCPTAHGIVLPGEKKCVSVFFHPKTLDTRTVDYCSIMPSGCASKTLLKVVGFCR 461
Query: 562 GPTFHFNVPALHFGDVSFG 580
GP ++F V+ G
Sbjct: 462 GPAVSLQHYCVNFSWVNLG 480
Score = 35.4 bits (80), Expect = 1.5
Identities = 55/235 (23%), Positives = 93/235 (39%), Gaps = 20/235 (8%)
Query: 640 FTISPDCGTIRPQGFAAIRVTLCSNTVQKYELALVVDVEGIGE------EVLALLITARC 693
F + P G + P + I+VT T YE+ G G ++ A+ A+
Sbjct: 286 FQMLPATGLLEPGQASQIKVTFQPLTAVIYEVQATCWY-GAGSRQRSSIQLQAVAKCAQL 344
Query: 694 VVPALHLVNTEVD---------FGHCFLKYPYEKTLQLANQDDLPGFYEVQPQVCEEVPT 744
+V H + D FG + E+ ++L N + + ++ E
Sbjct: 345 LVSIKHKCPEDQDAEGFQKLLYFGSVAVGCTSERQIRLHNPSAVNAPFRIEISPDELAED 404
Query: 745 VLFSSPTPSGVISPSSTIHIPLVLETQVTGEHRSTVYISIFGSQDPPLVCHLKSAG--EG 802
FS PT G++ P + + + T + R+ Y SI S LK G G
Sbjct: 405 QAFSCPTAHGIVLPGEKKCVSVFFHPK-TLDTRTVDYCSIMPSGCASKTL-LKVVGFCRG 462
Query: 803 PVIYVHPNQVDFGNIYVLKDSSRILNLCNQSFIPAFFQAHMAHKKSLWTIEPNEG 857
P + + V+F + + + S + L + NQS A FQ + +S++TI P G
Sbjct: 463 PAVSLQHYCVNFSWVNLGERSEQPLWIENQSDCTAHFQFAIDCLESVFTIRPAFG 517
Score = 35.4 bits (80), Expect = 1.5
Identities = 22/69 (31%), Positives = 34/69 (49%), Gaps = 1/69 (1%)
Query: 391 LVQGDSKLFFNNVFTVEPLEGDVWPNSSAEITVYFNPLEAKLYQQTIYCDILGREIRLPL 450
L Q K F + +F +G++ P S+A + F+P+EAK Y + ILG L +
Sbjct: 1340 LSQVQEKNFDHPIFCCLNPKGEIQPGSTARVLWIFSPIEAKTYTVDVPIHILGWNSAL-I 1398
Query: 451 RIKGEGMGP 459
+G G P
Sbjct: 1399 HFQGVGYNP 1407
Score = 34.3 bits (77), Expect = 3.3
Identities = 34/141 (24%), Positives = 55/141 (39%), Gaps = 28/141 (19%)
Query: 2472 YWDRKQGVQLPPA----------GMEEAPHEPDDQRQVPLG----GRRGRKDRERERLEK 2517
+ D+K + L P G + P E + LG G + + E E LE+
Sbjct: 1718 FMDQKNSLYLMPILPVPSSSWEDGKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEE 1777
Query: 2518 ERTEKERLEREKAERERLEKLRALEERSDWEGEGEEDHEGKKEKDLGVPFLDIQTPDF-E 2576
E E+E E E+ +E +E E EE+ + K+EK P+ E
Sbjct: 1778 EEEEEEETEEEELGKEEIE-------------EKEEERDEKEEKVSWAGIGPTPQPESQE 1824
Query: 2577 GLSWKQALESDKLPKGEQILD 2597
+ W+ + + + K EQ D
Sbjct: 1825 SMQWQWQQQLNVMVKEEQEQD 1845
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sapiens]
Length = 1293
Score = 60.5 bits (145), Expect = 4e-08
Identities = 63/272 (23%), Positives = 127/272 (46%), Gaps = 36/272 (13%)
Query: 2273 KAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKRE 2332
+A+ +AK+E+EERK + L +++E + +EE EEE+L R ++ALR ++RE
Sbjct: 737 EAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELA-RRKQEEALR--RQRE 793
Query: 2333 QERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKV 2392
QE + +E++ ERQ++E+ L+R ++ ++ EE K+ + KQ K
Sbjct: 794 QEIALRRQREEE-----ERQQQEEALRRLEERRRE----EEERRKQEELLRKQEEEAAKW 844
Query: 2393 DVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQL 2452
+ E +R++ E + +EE + + +++E + K+L
Sbjct: 845 AREEEEAQRRL--EENRLRMEEEAARLRH-------------EEEERKRKELEVQRQKEL 889
Query: 2453 APKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRER 2512
+ + + L+ +Q ++Q QL + + + E
Sbjct: 890 MRQRQQQQEALRRLQ------QQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEI 943
Query: 2513 ERLEKERTEKERLEREKAERERLEKLRALEER 2544
++LE+ER ER RE+ R++ E ++AL+++
Sbjct: 944 QKLEEER---ERQLREEQRRQQRELMKALQQQ 972
Score = 45.8 bits (107), Expect = 0.001
Identities = 38/176 (21%), Positives = 81/176 (46%), Gaps = 14/176 (7%)
Query: 2257 REHIYILNMAQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLT 2316
RE L ++ + QE+A + EER+ + +++E L EEE EE+
Sbjct: 792 REQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEA 851
Query: 2317 FDRGIQQALRERKK------REQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQG-- 2368
R + LR ++ E+ER KE++ ++ ++ + +++++ E RR+++ +Q
Sbjct: 852 QRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQ 911
Query: 2369 ------PIKEEPPMKKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNK 2418
P + + A + L+ +++ ER+ +RE+ ++ EL K
Sbjct: 912 LAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMK 967
Score = 45.4 bits (106), Expect = 0.001
Identities = 48/279 (17%), Positives = 119/279 (42%), Gaps = 22/279 (7%)
Query: 2257 REHIYILNMAQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLT 2316
+E I ++ + +E A+++QEE + ++E+E EE + +EE L
Sbjct: 759 QEEILRRQQEEERKRREEEELARRKQEEALRR---QREQEIALRRQREEEERQQQEEAL- 814
Query: 2317 FDRGIQQALRERKKREQERLAKEMQEKKLQQELER-QKEEDELKRRVKKGKQGPIKEEPP 2375
+ L ER++ E+ER +E +K ++E + +EE+E +RR+++ + +E
Sbjct: 815 ------RRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAAR 868
Query: 2376 MKKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQ 2435
++ + K+ K ++R+ + Q ++E L + ++ + + L
Sbjct: 869 LRHEEEERKR---------KELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPS 919
Query: 2436 DQEDSEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDD 2495
+ N+ Q + ++ + L R+Q +L A ++ +
Sbjct: 920 SSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQ--QQQQQ 977
Query: 2496 QRQVPLGGRRGRKDRERERLEKERTEKERLEREKAERER 2534
Q+ G + LE ++ E ++++++ ++++
Sbjct: 978 QKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQ 1016
Score = 38.9 bits (89), Expect = 0.13
Identities = 64/291 (21%), Positives = 124/291 (42%), Gaps = 39/291 (13%)
Query: 2287 HKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGI-----QQALRERKK-----REQERL 2336
H G L++E+ Q +E AL + + L + + + Q L +++K ++Q++L
Sbjct: 595 HMGELDQERLTRQ----QELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQL 650
Query: 2337 AKEMQE-KKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKV-DV 2394
A +Q+ + L+ + Q + R V G I E P A+ V V D+
Sbjct: 651 ALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPT----ASQPTVWEGGSVWDL 706
Query: 2395 KMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQLAP 2454
++T ++ + EK + K ++ + M +++E + + +++
Sbjct: 707 PLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKR--EEEERKRQEELRRQQEEILR 764
Query: 2455 KFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRERER 2514
+ + E ++ + + RKQ EEA QR+ + RR R++ ER++
Sbjct: 765 RQQEEERKRREEEELAR---RKQ---------EEALRR---QREQEIALRRQREEEERQQ 809
Query: 2515 LEKERTEKERLEREKAERERLEKL--RALEERSDWEGEGEEDHEGKKEKDL 2563
E+ E RE+ ER + E+L + EE + W E EE +E L
Sbjct: 810 QEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRL 860
Score = 36.6 bits (83), Expect = 0.66
Identities = 47/276 (17%), Positives = 108/276 (39%), Gaps = 17/276 (6%)
Query: 2267 QDYAAMKAQEKAKKEQEERKHKGALEKEKER-----LQNMDEEEYDALTEEEKLTFDRGI 2321
Q A + E K E+E + ++ ++R LQ +++ L+ ++ G
Sbjct: 933 QSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGT 992
Query: 2322 QQALRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQ--GPIKEEPPMKKS 2379
++L E ++ E ++ K+ Q+++ Q+ R + G G I PP +
Sbjct: 993 TKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPP---N 1049
Query: 2380 QAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQED 2439
Q A+ V + +T + + + E N +N + S+ V ++++
Sbjct: 1050 QWASDLVSSIWS---NADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQN 1106
Query: 2440 SEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPP----AGMEEAPHEPDD 2495
+ + + K K + + + +L + + +P E+P+E D
Sbjct: 1107 KKVEEEEKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHD 1166
Query: 2496 QRQVPLGGRRGRKDRERERLEKERTEKERLEREKAE 2531
+ LG K+ ++ LE+ +K +R++ +
Sbjct: 1167 YIRAYLGDTSEAKEFAKQFLERRAKQKANQQRQQQQ 1202
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sapiens]
Length = 1320
Score = 60.5 bits (145), Expect = 4e-08
Identities = 63/272 (23%), Positives = 127/272 (46%), Gaps = 36/272 (13%)
Query: 2273 KAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKRE 2332
+A+ +AK+E+EERK + L +++E + +EE EEE+L R ++ALR ++RE
Sbjct: 764 EAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELA-RRKQEEALR--RQRE 820
Query: 2333 QERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKV 2392
QE + +E++ ERQ++E+ L+R ++ ++ EE K+ + KQ K
Sbjct: 821 QEIALRRQREEE-----ERQQQEEALRRLEERRRE----EEERRKQEELLRKQEEEAAKW 871
Query: 2393 DVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQL 2452
+ E +R++ E + +EE + + +++E + K+L
Sbjct: 872 AREEEEAQRRL--EENRLRMEEEAARLRH-------------EEEERKRKELEVQRQKEL 916
Query: 2453 APKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRER 2512
+ + + L+ +Q ++Q QL + + + E
Sbjct: 917 MRQRQQQQEALRRLQ------QQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEI 970
Query: 2513 ERLEKERTEKERLEREKAERERLEKLRALEER 2544
++LE+ER ER RE+ R++ E ++AL+++
Sbjct: 971 QKLEEER---ERQLREEQRRQQRELMKALQQQ 999
Score = 45.8 bits (107), Expect = 0.001
Identities = 38/176 (21%), Positives = 81/176 (46%), Gaps = 14/176 (7%)
Query: 2257 REHIYILNMAQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLT 2316
RE L ++ + QE+A + EER+ + +++E L EEE EE+
Sbjct: 819 REQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEA 878
Query: 2317 FDRGIQQALRERKK------REQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQG-- 2368
R + LR ++ E+ER KE++ ++ ++ + +++++ E RR+++ +Q
Sbjct: 879 QRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQ 938
Query: 2369 ------PIKEEPPMKKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNK 2418
P + + A + L+ +++ ER+ +RE+ ++ EL K
Sbjct: 939 LAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMK 994
Score = 45.4 bits (106), Expect = 0.001
Identities = 48/279 (17%), Positives = 119/279 (42%), Gaps = 22/279 (7%)
Query: 2257 REHIYILNMAQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLT 2316
+E I ++ + +E A+++QEE + ++E+E EE + +EE L
Sbjct: 786 QEEILRRQQEEERKRREEEELARRKQEEALRR---QREQEIALRRQREEEERQQQEEAL- 841
Query: 2317 FDRGIQQALRERKKREQERLAKEMQEKKLQQELER-QKEEDELKRRVKKGKQGPIKEEPP 2375
+ L ER++ E+ER +E +K ++E + +EE+E +RR+++ + +E
Sbjct: 842 ------RRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAAR 895
Query: 2376 MKKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQ 2435
++ + K+ K ++R+ + Q ++E L + ++ + + L
Sbjct: 896 LRHEEEERKR---------KELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPS 946
Query: 2436 DQEDSEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDD 2495
+ N+ Q + ++ + L R+Q +L A ++ +
Sbjct: 947 SSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQ--QQQQQ 1004
Query: 2496 QRQVPLGGRRGRKDRERERLEKERTEKERLEREKAERER 2534
Q+ G + LE ++ E ++++++ ++++
Sbjct: 1005 QKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQ 1043
Score = 38.9 bits (89), Expect = 0.13
Identities = 64/291 (21%), Positives = 124/291 (42%), Gaps = 39/291 (13%)
Query: 2287 HKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGI-----QQALRERKK-----REQERL 2336
H G L++E+ Q +E AL + + L + + + Q L +++K ++Q++L
Sbjct: 622 HMGELDQERLTRQ----QELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQL 677
Query: 2337 AKEMQE-KKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKV-DV 2394
A +Q+ + L+ + Q + R V G I E P A+ V V D+
Sbjct: 678 ALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPT----ASQPTVWEGGSVWDL 733
Query: 2395 KMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQLAP 2454
++T ++ + EK + K ++ + M +++E + + +++
Sbjct: 734 PLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKR--EEEERKRQEELRRQQEEILR 791
Query: 2455 KFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRERER 2514
+ + E ++ + + RKQ EEA QR+ + RR R++ ER++
Sbjct: 792 RQQEEERKRREEEELAR---RKQ---------EEALRR---QREQEIALRRQREEEERQQ 836
Query: 2515 LEKERTEKERLEREKAERERLEKL--RALEERSDWEGEGEEDHEGKKEKDL 2563
E+ E RE+ ER + E+L + EE + W E EE +E L
Sbjct: 837 QEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRL 887
Score = 36.6 bits (83), Expect = 0.66
Identities = 47/276 (17%), Positives = 108/276 (39%), Gaps = 17/276 (6%)
Query: 2267 QDYAAMKAQEKAKKEQEERKHKGALEKEKER-----LQNMDEEEYDALTEEEKLTFDRGI 2321
Q A + E K E+E + ++ ++R LQ +++ L+ ++ G
Sbjct: 960 QSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGT 1019
Query: 2322 QQALRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQ--GPIKEEPPMKKS 2379
++L E ++ E ++ K+ Q+++ Q+ R + G G I PP +
Sbjct: 1020 TKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPP---N 1076
Query: 2380 QAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQED 2439
Q A+ V + +T + + + E N +N + S+ V ++++
Sbjct: 1077 QWASDLVSSIWS---NADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQN 1133
Query: 2440 SEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPP----AGMEEAPHEPDD 2495
+ + + K K + + + +L + + +P E+P+E D
Sbjct: 1134 KKVEEEEKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHD 1193
Query: 2496 QRQVPLGGRRGRKDRERERLEKERTEKERLEREKAE 2531
+ LG K+ ++ LE+ +K +R++ +
Sbjct: 1194 YIRAYLGDTSEAKEFAKQFLERRAKQKANQQRQQQQ 1229
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sapiens]
Length = 1299
Score = 60.5 bits (145), Expect = 4e-08
Identities = 63/272 (23%), Positives = 127/272 (46%), Gaps = 36/272 (13%)
Query: 2273 KAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKRE 2332
+A+ +AK+E+EERK + L +++E + +EE EEE+L R ++ALR ++RE
Sbjct: 743 EAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELA-RRKQEEALR--RQRE 799
Query: 2333 QERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKV 2392
QE + +E++ ERQ++E+ L+R ++ ++ EE K+ + KQ K
Sbjct: 800 QEIALRRQREEE-----ERQQQEEALRRLEERRRE----EEERRKQEELLRKQEEEAAKW 850
Query: 2393 DVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQL 2452
+ E +R++ E + +EE + + +++E + K+L
Sbjct: 851 AREEEEAQRRL--EENRLRMEEEAARLRH-------------EEEERKRKELEVQRQKEL 895
Query: 2453 APKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRER 2512
+ + + L+ +Q ++Q QL + + + E
Sbjct: 896 MRQRQQQQEALRRLQ------QQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEI 949
Query: 2513 ERLEKERTEKERLEREKAERERLEKLRALEER 2544
++LE+ER ER RE+ R++ E ++AL+++
Sbjct: 950 QKLEEER---ERQLREEQRRQQRELMKALQQQ 978
Score = 45.8 bits (107), Expect = 0.001
Identities = 38/176 (21%), Positives = 81/176 (46%), Gaps = 14/176 (7%)
Query: 2257 REHIYILNMAQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLT 2316
RE L ++ + QE+A + EER+ + +++E L EEE EE+
Sbjct: 798 REQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEA 857
Query: 2317 FDRGIQQALRERKK------REQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQG-- 2368
R + LR ++ E+ER KE++ ++ ++ + +++++ E RR+++ +Q
Sbjct: 858 QRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQ 917
Query: 2369 ------PIKEEPPMKKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNK 2418
P + + A + L+ +++ ER+ +RE+ ++ EL K
Sbjct: 918 LAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMK 973
Score = 45.4 bits (106), Expect = 0.001
Identities = 48/279 (17%), Positives = 119/279 (42%), Gaps = 22/279 (7%)
Query: 2257 REHIYILNMAQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLT 2316
+E I ++ + +E A+++QEE + ++E+E EE + +EE L
Sbjct: 765 QEEILRRQQEEERKRREEEELARRKQEEALRR---QREQEIALRRQREEEERQQQEEAL- 820
Query: 2317 FDRGIQQALRERKKREQERLAKEMQEKKLQQELER-QKEEDELKRRVKKGKQGPIKEEPP 2375
+ L ER++ E+ER +E +K ++E + +EE+E +RR+++ + +E
Sbjct: 821 ------RRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAAR 874
Query: 2376 MKKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQ 2435
++ + K+ K ++R+ + Q ++E L + ++ + + L
Sbjct: 875 LRHEEEERKR---------KELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPS 925
Query: 2436 DQEDSEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDD 2495
+ N+ Q + ++ + L R+Q +L A ++ +
Sbjct: 926 SSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQ--QQQQQ 983
Query: 2496 QRQVPLGGRRGRKDRERERLEKERTEKERLEREKAERER 2534
Q+ G + LE ++ E ++++++ ++++
Sbjct: 984 QKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQ 1022
Score = 38.9 bits (89), Expect = 0.13
Identities = 64/291 (21%), Positives = 124/291 (42%), Gaps = 39/291 (13%)
Query: 2287 HKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGI-----QQALRERKK-----REQERL 2336
H G L++E+ Q +E AL + + L + + + Q L +++K ++Q++L
Sbjct: 601 HMGELDQERLTRQ----QELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQL 656
Query: 2337 AKEMQE-KKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKV-DV 2394
A +Q+ + L+ + Q + R V G I E P A+ V V D+
Sbjct: 657 ALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPT----ASQPTVWEGGSVWDL 712
Query: 2395 KMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQLAP 2454
++T ++ + EK + K ++ + M +++E + + +++
Sbjct: 713 PLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKR--EEEERKRQEELRRQQEEILR 770
Query: 2455 KFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRERER 2514
+ + E ++ + + RKQ EEA QR+ + RR R++ ER++
Sbjct: 771 RQQEEERKRREEEELAR---RKQ---------EEALRR---QREQEIALRRQREEEERQQ 815
Query: 2515 LEKERTEKERLEREKAERERLEKL--RALEERSDWEGEGEEDHEGKKEKDL 2563
E+ E RE+ ER + E+L + EE + W E EE +E L
Sbjct: 816 QEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRL 866
Score = 36.6 bits (83), Expect = 0.66
Identities = 47/276 (17%), Positives = 108/276 (39%), Gaps = 17/276 (6%)
Query: 2267 QDYAAMKAQEKAKKEQEERKHKGALEKEKER-----LQNMDEEEYDALTEEEKLTFDRGI 2321
Q A + E K E+E + ++ ++R LQ +++ L+ ++ G
Sbjct: 939 QSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGT 998
Query: 2322 QQALRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQ--GPIKEEPPMKKS 2379
++L E ++ E ++ K+ Q+++ Q+ R + G G I PP +
Sbjct: 999 TKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPP---N 1055
Query: 2380 QAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQED 2439
Q A+ V + +T + + + E N +N + S+ V ++++
Sbjct: 1056 QWASDLVSSIWS---NADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQN 1112
Query: 2440 SEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPP----AGMEEAPHEPDD 2495
+ + + K K + + + +L + + +P E+P+E D
Sbjct: 1113 KKVEEEEKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHD 1172
Query: 2496 QRQVPLGGRRGRKDRERERLEKERTEKERLEREKAE 2531
+ LG K+ ++ LE+ +K +R++ +
Sbjct: 1173 YIRAYLGDTSEAKEFAKQFLERRAKQKANQQRQQQQ 1208
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.135 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 202,986,823
Number of Sequences: 37866
Number of extensions: 9893038
Number of successful extensions: 58079
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 270
Number of HSP's successfully gapped in prelim test: 931
Number of HSP's that attempted gapping in prelim test: 32972
Number of HSP's gapped (non-prelim): 12719
length of query: 5120
length of database: 18,247,518
effective HSP length: 124
effective length of query: 4996
effective length of database: 13,552,134
effective search space: 67706461464
effective search space used: 67706461464
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 73 (32.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.