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Search of human proteins with 11968009
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|11968009 SIL1 protein precursor [Homo sapiens]
(461 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|11968009 SIL1 protein precursor [Homo sapiens] 898 0.0
gi|83641896 SIL1 protein precursor [Homo sapiens] 898 0.0
gi|194294548 hsp70-interacting protein [Homo sapiens] 54 3e-07
gi|112363070 hsp70-interacting protein [Homo sapiens] 54 3e-07
gi|19924131 RAD50 homolog isoform 2 [Homo sapiens] 42 0.002
gi|19924129 RAD50 homolog isoform 1 [Homo sapiens] 42 0.002
gi|226958575 RAS protein activator like 2 isoform 2 [Homo sapiens] 40 0.003
gi|4758808 RAS protein activator like 2 isoform 1 [Homo sapiens] 40 0.003
gi|6912678 sperm associated antigen 6 isoform 1 [Homo sapiens] 40 0.004
gi|27262641 sperm associated antigen 6 isoform 2 [Homo sapiens] 40 0.004
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 37 0.038
gi|4758648 kinesin family member 5B [Homo sapiens] 37 0.049
gi|170650672 Leber congenital amaurosis 5 [Homo sapiens] 37 0.049
gi|170650670 Leber congenital amaurosis 5 [Homo sapiens] 37 0.049
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 36 0.064
gi|7705415 hook homolog 1 [Homo sapiens] 36 0.084
gi|29540566 armadillo repeat containing, X-linked 3 [Homo sapiens] 35 0.11
gi|29540564 armadillo repeat containing, X-linked 3 [Homo sapiens] 35 0.11
gi|7705274 armadillo repeat containing, X-linked 3 [Homo sapiens] 35 0.11
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 35 0.19
gi|118600973 RNA binding motif protein, X-linked 2 [Homo sapiens] 35 0.19
gi|68299795 chromodomain helicase DNA binding protein 1 [Homo sa... 35 0.19
gi|29294627 PTPRF interacting protein binding protein 1 isoform ... 34 0.24
gi|4758650 kinesin family member 5C [Homo sapiens] 34 0.32
gi|41281683 disabled homolog 2 interacting protein isoform 2 [Ho... 34 0.32
gi|211059433 coiled-coil domain containing 79 [Homo sapiens] 34 0.32
gi|148839339 nexilin (F actin binding protein) [Homo sapiens] 34 0.32
gi|37588869 ring finger protein 123 [Homo sapiens] 33 0.42
gi|150170718 zinc finger protein 292 [Homo sapiens] 33 0.42
gi|7662162 ALEX2 protein [Homo sapiens] 33 0.42
>gi|11968009 SIL1 protein precursor [Homo sapiens]
Length = 461
Score = 898 bits (2321), Expect = 0.0
Identities = 461/461 (100%), Positives = 461/461 (100%)
Query: 1 MAPQSLPSSRMAPLGMLLGLLMAACFTFCLSHQNLKEFALTNPEKSSTKETERKETKAEE 60
MAPQSLPSSRMAPLGMLLGLLMAACFTFCLSHQNLKEFALTNPEKSSTKETERKETKAEE
Sbjct: 1 MAPQSLPSSRMAPLGMLLGLLMAACFTFCLSHQNLKEFALTNPEKSSTKETERKETKAEE 60
Query: 61 ELDAEVLEVFHPTHEWQALQPGQAVPAGSHVRLNLQTGEREAKLQYEDKFRNNLKGKRLD 120
ELDAEVLEVFHPTHEWQALQPGQAVPAGSHVRLNLQTGEREAKLQYEDKFRNNLKGKRLD
Sbjct: 61 ELDAEVLEVFHPTHEWQALQPGQAVPAGSHVRLNLQTGEREAKLQYEDKFRNNLKGKRLD 120
Query: 121 INTNTYTSQDLKSALAKFKEGAEMESSKEDKARQAEVKRLFRPIEELKKDFDELNVVIET 180
INTNTYTSQDLKSALAKFKEGAEMESSKEDKARQAEVKRLFRPIEELKKDFDELNVVIET
Sbjct: 121 INTNTYTSQDLKSALAKFKEGAEMESSKEDKARQAEVKRLFRPIEELKKDFDELNVVIET 180
Query: 181 DMQIMVRLINKFNSSSSSLEEKIAALFDLEYYVHQMDNAQDLLSFGGLQVVINGLNSTEP 240
DMQIMVRLINKFNSSSSSLEEKIAALFDLEYYVHQMDNAQDLLSFGGLQVVINGLNSTEP
Sbjct: 181 DMQIMVRLINKFNSSSSSLEEKIAALFDLEYYVHQMDNAQDLLSFGGLQVVINGLNSTEP 240
Query: 241 LVKEYAAFVLGAAFSSNPKVQVEAIEGGALQKLLVILATEQPLTAKKKVLFALCSLLRHF 300
LVKEYAAFVLGAAFSSNPKVQVEAIEGGALQKLLVILATEQPLTAKKKVLFALCSLLRHF
Sbjct: 241 LVKEYAAFVLGAAFSSNPKVQVEAIEGGALQKLLVILATEQPLTAKKKVLFALCSLLRHF 300
Query: 301 PYAQRQFLKLGGLQVLRTLVQEKGTEVLAVRVVTLLYDLVTEKMFAEEEAELTQEMSPEK 360
PYAQRQFLKLGGLQVLRTLVQEKGTEVLAVRVVTLLYDLVTEKMFAEEEAELTQEMSPEK
Sbjct: 301 PYAQRQFLKLGGLQVLRTLVQEKGTEVLAVRVVTLLYDLVTEKMFAEEEAELTQEMSPEK 360
Query: 361 LQQYRQVHLLPGLWEQGWCEITAHLLALPEHDAREKVLQTLGVLLTTCRDRYRQDPQLGR 420
LQQYRQVHLLPGLWEQGWCEITAHLLALPEHDAREKVLQTLGVLLTTCRDRYRQDPQLGR
Sbjct: 361 LQQYRQVHLLPGLWEQGWCEITAHLLALPEHDAREKVLQTLGVLLTTCRDRYRQDPQLGR 420
Query: 421 TLASLQAEYQVLASLELQDGEDEGYFQELLGSVNSLLKELR 461
TLASLQAEYQVLASLELQDGEDEGYFQELLGSVNSLLKELR
Sbjct: 421 TLASLQAEYQVLASLELQDGEDEGYFQELLGSVNSLLKELR 461
>gi|83641896 SIL1 protein precursor [Homo sapiens]
Length = 461
Score = 898 bits (2321), Expect = 0.0
Identities = 461/461 (100%), Positives = 461/461 (100%)
Query: 1 MAPQSLPSSRMAPLGMLLGLLMAACFTFCLSHQNLKEFALTNPEKSSTKETERKETKAEE 60
MAPQSLPSSRMAPLGMLLGLLMAACFTFCLSHQNLKEFALTNPEKSSTKETERKETKAEE
Sbjct: 1 MAPQSLPSSRMAPLGMLLGLLMAACFTFCLSHQNLKEFALTNPEKSSTKETERKETKAEE 60
Query: 61 ELDAEVLEVFHPTHEWQALQPGQAVPAGSHVRLNLQTGEREAKLQYEDKFRNNLKGKRLD 120
ELDAEVLEVFHPTHEWQALQPGQAVPAGSHVRLNLQTGEREAKLQYEDKFRNNLKGKRLD
Sbjct: 61 ELDAEVLEVFHPTHEWQALQPGQAVPAGSHVRLNLQTGEREAKLQYEDKFRNNLKGKRLD 120
Query: 121 INTNTYTSQDLKSALAKFKEGAEMESSKEDKARQAEVKRLFRPIEELKKDFDELNVVIET 180
INTNTYTSQDLKSALAKFKEGAEMESSKEDKARQAEVKRLFRPIEELKKDFDELNVVIET
Sbjct: 121 INTNTYTSQDLKSALAKFKEGAEMESSKEDKARQAEVKRLFRPIEELKKDFDELNVVIET 180
Query: 181 DMQIMVRLINKFNSSSSSLEEKIAALFDLEYYVHQMDNAQDLLSFGGLQVVINGLNSTEP 240
DMQIMVRLINKFNSSSSSLEEKIAALFDLEYYVHQMDNAQDLLSFGGLQVVINGLNSTEP
Sbjct: 181 DMQIMVRLINKFNSSSSSLEEKIAALFDLEYYVHQMDNAQDLLSFGGLQVVINGLNSTEP 240
Query: 241 LVKEYAAFVLGAAFSSNPKVQVEAIEGGALQKLLVILATEQPLTAKKKVLFALCSLLRHF 300
LVKEYAAFVLGAAFSSNPKVQVEAIEGGALQKLLVILATEQPLTAKKKVLFALCSLLRHF
Sbjct: 241 LVKEYAAFVLGAAFSSNPKVQVEAIEGGALQKLLVILATEQPLTAKKKVLFALCSLLRHF 300
Query: 301 PYAQRQFLKLGGLQVLRTLVQEKGTEVLAVRVVTLLYDLVTEKMFAEEEAELTQEMSPEK 360
PYAQRQFLKLGGLQVLRTLVQEKGTEVLAVRVVTLLYDLVTEKMFAEEEAELTQEMSPEK
Sbjct: 301 PYAQRQFLKLGGLQVLRTLVQEKGTEVLAVRVVTLLYDLVTEKMFAEEEAELTQEMSPEK 360
Query: 361 LQQYRQVHLLPGLWEQGWCEITAHLLALPEHDAREKVLQTLGVLLTTCRDRYRQDPQLGR 420
LQQYRQVHLLPGLWEQGWCEITAHLLALPEHDAREKVLQTLGVLLTTCRDRYRQDPQLGR
Sbjct: 361 LQQYRQVHLLPGLWEQGWCEITAHLLALPEHDAREKVLQTLGVLLTTCRDRYRQDPQLGR 420
Query: 421 TLASLQAEYQVLASLELQDGEDEGYFQELLGSVNSLLKELR 461
TLASLQAEYQVLASLELQDGEDEGYFQELLGSVNSLLKELR
Sbjct: 421 TLASLQAEYQVLASLELQDGEDEGYFQELLGSVNSLLKELR 461
>gi|194294548 hsp70-interacting protein [Homo sapiens]
Length = 359
Score = 53.9 bits (128), Expect = 3e-07
Identities = 42/142 (29%), Positives = 71/142 (50%), Gaps = 2/142 (1%)
Query: 200 EEKIAALFDLEYYVHQMDNAQDLLSFGGLQVVING-LNSTEPLVKEYAAFVLGAAFSSNP 258
+E+ AL L MDNA D G+ +++ L + ++ AA ++G +
Sbjct: 118 QEREGALELLADLCENMDNAADFCQLSGMHLLVGRYLEAGAAGLRWRAAQLIGTCSQNVA 177
Query: 259 KVQVEAIEGGALQKLLVILATEQPLTAKKKVLFALCSLLRHFPYAQRQFLKLGGLQVLRT 318
+Q + + GAL+KLL +L + T + K LFA+ L+R QFL+L G VL
Sbjct: 178 AIQEQVLGLGALRKLLRLLDRDACDTVRVKALFAISCLVREQEAGLLQFLRLDGFSVLMR 237
Query: 319 LVQEKGTEVLAVRVVTLLYDLV 340
+Q++ + L V+ LL +L+
Sbjct: 238 AMQQQ-VQKLKVKSAFLLQNLL 258
Score = 37.4 bits (85), Expect = 0.029
Identities = 27/106 (25%), Positives = 49/106 (46%), Gaps = 2/106 (1%)
Query: 202 KIAALFDLEYYVHQMD-NAQDLLSFGGLQVVINGLNSTEPLVKEYAAFVLGAAFSSNPKV 260
++ ALF + V + + L G V++ + +K +AF+L +P+
Sbjct: 205 RVKALFAISCLVREQEAGLLQFLRLDGFSVLMRAMQQQVQKLKVKSAFLLQNLLVGHPEH 264
Query: 261 QVEAIEGGALQKLLVILATEQPLTAKKKVLFALCSLLRHFPYAQRQ 306
+ G +Q+L+ ++ TE + VL ALCSL+ FP R+
Sbjct: 265 KGTLCSMGMVQQLVALVRTEHS-PFHEHVLGALCSLVTDFPQGVRE 309
>gi|112363070 hsp70-interacting protein [Homo sapiens]
Length = 359
Score = 53.9 bits (128), Expect = 3e-07
Identities = 42/142 (29%), Positives = 71/142 (50%), Gaps = 2/142 (1%)
Query: 200 EEKIAALFDLEYYVHQMDNAQDLLSFGGLQVVING-LNSTEPLVKEYAAFVLGAAFSSNP 258
+E+ AL L MDNA D G+ +++ L + ++ AA ++G +
Sbjct: 118 QEREGALELLADLCENMDNAADFCQLSGMHLLVGRYLEAGAAGLRWRAAQLIGTCSQNVA 177
Query: 259 KVQVEAIEGGALQKLLVILATEQPLTAKKKVLFALCSLLRHFPYAQRQFLKLGGLQVLRT 318
+Q + + GAL+KLL +L + T + K LFA+ L+R QFL+L G VL
Sbjct: 178 AIQEQVLGLGALRKLLRLLDRDACDTVRVKALFAISCLVREQEAGLLQFLRLDGFSVLMR 237
Query: 319 LVQEKGTEVLAVRVVTLLYDLV 340
+Q++ + L V+ LL +L+
Sbjct: 238 AMQQQ-VQKLKVKSAFLLQNLL 258
Score = 37.4 bits (85), Expect = 0.029
Identities = 27/106 (25%), Positives = 49/106 (46%), Gaps = 2/106 (1%)
Query: 202 KIAALFDLEYYVHQMD-NAQDLLSFGGLQVVINGLNSTEPLVKEYAAFVLGAAFSSNPKV 260
++ ALF + V + + L G V++ + +K +AF+L +P+
Sbjct: 205 RVKALFAISCLVREQEAGLLQFLRLDGFSVLMRAMQQQVQKLKVKSAFLLQNLLVGHPEH 264
Query: 261 QVEAIEGGALQKLLVILATEQPLTAKKKVLFALCSLLRHFPYAQRQ 306
+ G +Q+L+ ++ TE + VL ALCSL+ FP R+
Sbjct: 265 KGTLCSMGMVQQLVALVRTEHS-PFHEHVLGALCSLVTDFPQGVRE 309
>gi|19924131 RAD50 homolog isoform 2 [Homo sapiens]
Length = 1173
Score = 41.6 bits (96), Expect = 0.002
Identities = 26/105 (24%), Positives = 48/105 (45%), Gaps = 15/105 (14%)
Query: 99 EREAKLQYEDKFRNNLKGKRLDINTNTYTSQDLKSALAKFKEGAEMESSKEDKARQAEVK 158
+++ ++Q+ N LK ++L I+TN Q L+ + EV+
Sbjct: 716 DQQEQIQHLKSTTNELKSEKLQISTNLQRRQQLEEQTVELS---------------TEVQ 760
Query: 159 RLFRPIEELKKDFDELNVVIETDMQIMVRLINKFNSSSSSLEEKI 203
L+R I++ K+ L +E Q LINK N+S+ ++K+
Sbjct: 761 SLYREIKDAKEQVSPLETTLEKFQQEKEELINKKNTSNKIAQDKL 805
>gi|19924129 RAD50 homolog isoform 1 [Homo sapiens]
Length = 1312
Score = 41.6 bits (96), Expect = 0.002
Identities = 26/105 (24%), Positives = 48/105 (45%), Gaps = 15/105 (14%)
Query: 99 EREAKLQYEDKFRNNLKGKRLDINTNTYTSQDLKSALAKFKEGAEMESSKEDKARQAEVK 158
+++ ++Q+ N LK ++L I+TN Q L+ + EV+
Sbjct: 855 DQQEQIQHLKSTTNELKSEKLQISTNLQRRQQLEEQTVELS---------------TEVQ 899
Query: 159 RLFRPIEELKKDFDELNVVIETDMQIMVRLINKFNSSSSSLEEKI 203
L+R I++ K+ L +E Q LINK N+S+ ++K+
Sbjct: 900 SLYREIKDAKEQVSPLETTLEKFQQEKEELINKKNTSNKIAQDKL 944
>gi|226958575 RAS protein activator like 2 isoform 2 [Homo sapiens]
Length = 1280
Score = 40.4 bits (93), Expect = 0.003
Identities = 60/255 (23%), Positives = 102/255 (40%), Gaps = 28/255 (10%)
Query: 2 APQSLPSSRMAPLGMLLGLLMAACFTFCLSHQNLKEFALTNPEKSSTKET--------ER 53
AP SLP S + ++ AA L + ++ + + + SS++E+ +R
Sbjct: 1025 APPSLPHSASLRSTGSMSVVSAA-----LVAEPVQNGSRSRQQSSSSRESPVPKVRAIQR 1079
Query: 54 KETK-AEEELDAEVLEVFHPTHEWQALQPGQAVPAGSHVRLNLQTGEREAKLQYED---K 109
++T+ + +D+ + T W L GQ NL + K + E K
Sbjct: 1080 QQTQQVQSPVDSATMSPVERTAAW-VLNNGQYEEDVEETEQNLDEAKHAEKYEQEITKLK 1138
Query: 110 FRNNLKGKRLDINTNTYTSQDLKSALAKFKEGAEMESSKEDKARQAEVK---------RL 160
R + +RL+ Q+ + + A +E S+E RQ E K RL
Sbjct: 1139 ERLRVSSRRLEEYERRLLVQEQQMQKLLLEYKARLEDSEERLRRQQEEKDSQMKSIISRL 1198
Query: 161 FRPIEELKKDFDELNVVIETDMQIMVRLINKFNSSSSSLEEKIAALFDL-EYYVHQMDNA 219
EELKKD E+ VI+ +I+ + S S+ ++AL + E Y Q+ N
Sbjct: 1199 MAVEEELKKDHAEMQAVIDAKQKIIDAQEKRIVSLDSANTRLMSALTQVKERYSMQVRNG 1258
Query: 220 QDLLSFGGLQVVING 234
+ L + NG
Sbjct: 1259 ISPTNPTKLSITENG 1273
>gi|4758808 RAS protein activator like 2 isoform 1 [Homo sapiens]
Length = 1139
Score = 40.4 bits (93), Expect = 0.003
Identities = 60/255 (23%), Positives = 102/255 (40%), Gaps = 28/255 (10%)
Query: 2 APQSLPSSRMAPLGMLLGLLMAACFTFCLSHQNLKEFALTNPEKSSTKET--------ER 53
AP SLP S + ++ AA L + ++ + + + SS++E+ +R
Sbjct: 884 APPSLPHSASLRSTGSMSVVSAA-----LVAEPVQNGSRSRQQSSSSRESPVPKVRAIQR 938
Query: 54 KETK-AEEELDAEVLEVFHPTHEWQALQPGQAVPAGSHVRLNLQTGEREAKLQYED---K 109
++T+ + +D+ + T W L GQ NL + K + E K
Sbjct: 939 QQTQQVQSPVDSATMSPVERTAAW-VLNNGQYEEDVEETEQNLDEAKHAEKYEQEITKLK 997
Query: 110 FRNNLKGKRLDINTNTYTSQDLKSALAKFKEGAEMESSKEDKARQAEVK---------RL 160
R + +RL+ Q+ + + A +E S+E RQ E K RL
Sbjct: 998 ERLRVSSRRLEEYERRLLVQEQQMQKLLLEYKARLEDSEERLRRQQEEKDSQMKSIISRL 1057
Query: 161 FRPIEELKKDFDELNVVIETDMQIMVRLINKFNSSSSSLEEKIAALFDL-EYYVHQMDNA 219
EELKKD E+ VI+ +I+ + S S+ ++AL + E Y Q+ N
Sbjct: 1058 MAVEEELKKDHAEMQAVIDAKQKIIDAQEKRIVSLDSANTRLMSALTQVKERYSMQVRNG 1117
Query: 220 QDLLSFGGLQVVING 234
+ L + NG
Sbjct: 1118 ISPTNPTKLSITENG 1132
>gi|6912678 sperm associated antigen 6 isoform 1 [Homo sapiens]
Length = 509
Score = 40.0 bits (92), Expect = 0.004
Identities = 27/107 (25%), Positives = 48/107 (44%), Gaps = 1/107 (0%)
Query: 214 HQMDNAQDLLSFGGLQVVINGLNSTEPLVKEYAAFVLGAAFSSNPKVQVEAIEGGALQKL 273
H AQ ++ G L ++ L +P VKE AA+ L N ++ ++ GA+ L
Sbjct: 113 HSPQLAQAIVDCGALDTLVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAV-PL 171
Query: 274 LVILATEQPLTAKKKVLFALCSLLRHFPYAQRQFLKLGGLQVLRTLV 320
LV+ E + K+ AL + +H P + + G + L ++
Sbjct: 172 LVLCIQEPEIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMI 218
Score = 34.7 bits (78), Expect = 0.19
Identities = 27/106 (25%), Positives = 48/106 (45%), Gaps = 1/106 (0%)
Query: 217 DNAQDLLSFGGLQVVINGLNSTEPLVKEYAAFVLGAAFSSNPKVQVEAIEGGALQKLLVI 276
D A+ ++ L ++ L K+ AAFVL A +P++ ++ GAL L++
Sbjct: 74 DLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQAIVDCGALDTLVIC 133
Query: 277 LATEQPLTAKKKVLFALCSLLRHFPYAQRQFLKLGGLQVLRTLVQE 322
L P K+ +AL + RH + + G + +L +QE
Sbjct: 134 LEDFDP-GVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQE 178
Score = 30.4 bits (67), Expect = 3.5
Identities = 37/165 (22%), Positives = 69/165 (41%), Gaps = 4/165 (2%)
Query: 168 KKDFDELNVVIETDMQIMVRLINKFNSSSSSLEEKIAALFDLEYYVHQMDNAQDLLSFGG 227
K D +V+E ++ +V K +K A+ E H + +Q +++ GG
Sbjct: 238 KHSVDLAEMVVEAEIFPVVLTCLK---DKDEYVKKNASTLIREIAKHTPELSQLVVNAGG 294
Query: 228 LQVVINGLNSTEPLVKEYAAFVLGAAFSSNPKVQVEAIEGGALQKLLVILATEQPLTAKK 287
+ VI+ + S + + +LG + + + + I + +L V L+ E K
Sbjct: 295 VAAVIDCIGSCKGNTRLPGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPEDHIKA 354
Query: 288 KVLFALCSLLRHFPYAQRQFLKLGGLQVLRTL-VQEKGTEVLAVR 331
+AL + RH P R L VL +L + + +E L V+
Sbjct: 355 AAAWALGQIGRHTPEHARAVAVTNTLPVLLSLYMSTESSEDLQVK 399
>gi|27262641 sperm associated antigen 6 isoform 2 [Homo sapiens]
Length = 458
Score = 40.0 bits (92), Expect = 0.004
Identities = 27/107 (25%), Positives = 48/107 (44%), Gaps = 1/107 (0%)
Query: 214 HQMDNAQDLLSFGGLQVVINGLNSTEPLVKEYAAFVLGAAFSSNPKVQVEAIEGGALQKL 273
H AQ ++ G L ++ L +P VKE AA+ L N ++ ++ GA+ L
Sbjct: 113 HSPQLAQAIVDCGALDTLVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAV-PL 171
Query: 274 LVILATEQPLTAKKKVLFALCSLLRHFPYAQRQFLKLGGLQVLRTLV 320
LV+ E + K+ AL + +H P + + G + L ++
Sbjct: 172 LVLCIQEPEIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMI 218
Score = 34.7 bits (78), Expect = 0.19
Identities = 27/106 (25%), Positives = 48/106 (45%), Gaps = 1/106 (0%)
Query: 217 DNAQDLLSFGGLQVVINGLNSTEPLVKEYAAFVLGAAFSSNPKVQVEAIEGGALQKLLVI 276
D A+ ++ L ++ L K+ AAFVL A +P++ ++ GAL L++
Sbjct: 74 DLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQAIVDCGALDTLVIC 133
Query: 277 LATEQPLTAKKKVLFALCSLLRHFPYAQRQFLKLGGLQVLRTLVQE 322
L P K+ +AL + RH + + G + +L +QE
Sbjct: 134 LEDFDP-GVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQE 178
Score = 30.4 bits (67), Expect = 3.5
Identities = 37/165 (22%), Positives = 69/165 (41%), Gaps = 4/165 (2%)
Query: 168 KKDFDELNVVIETDMQIMVRLINKFNSSSSSLEEKIAALFDLEYYVHQMDNAQDLLSFGG 227
K D +V+E ++ +V K +K A+ E H + +Q +++ GG
Sbjct: 238 KHSVDLAEMVVEAEIFPVVLTCLK---DKDEYVKKNASTLIREIAKHTPELSQLVVNAGG 294
Query: 228 LQVVINGLNSTEPLVKEYAAFVLGAAFSSNPKVQVEAIEGGALQKLLVILATEQPLTAKK 287
+ VI+ + S + + +LG + + + + I + +L V L+ E K
Sbjct: 295 VAAVIDCIGSCKGNTRLPGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPEDHIKA 354
Query: 288 KVLFALCSLLRHFPYAQRQFLKLGGLQVLRTL-VQEKGTEVLAVR 331
+AL + RH P R L VL +L + + +E L V+
Sbjct: 355 AAAWALGQIGRHTPEHARAVAVTNTLPVLLSLYMSTESSEDLQVK 399
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 37.0 bits (84), Expect = 0.038
Identities = 89/448 (19%), Positives = 171/448 (38%), Gaps = 48/448 (10%)
Query: 31 SHQNLKEF----ALTNPEKSSTKETERKETKAEEELDAEVLEVFHPTHEWQALQPGQAVP 86
SH+ L++ ++ E +E + T + L AE EV + +A G+
Sbjct: 664 SHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEA---GRVEL 720
Query: 87 AGSHVRLNLQTGEREAKLQYEDKFRNNLKGKRLDINTNTYTSQDLKSALAKFKEGAEMES 146
S +L + + L +L +LD+N ++ KSAL + AE E+
Sbjct: 721 ELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEA 780
Query: 147 SKEDKARQAEVKRLFRPIEELKKDFDELNVVIETDMQIMVRLINKFNSSSSSLEEKIAAL 206
+ + Q ++ L E ++ + V E + + + + S L+E++A L
Sbjct: 781 TVA-REEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQL 839
Query: 207 F-DLEYYVHQMDNAQDLLSFGGLQVVINGLNSTEPLVKEYAAFVL--------GAAFSSN 257
L +++ A+ ++ + E L KE+A + G S
Sbjct: 840 SRQLSGREQELEQARREAQ-RQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEE 898
Query: 258 P---KVQVEAIEGGALQ---KLLVILATEQPLTAKKKVLFALCSLLRHFPYAQRQFLKLG 311
+++ EA+EG + +L + A + L A+ + L L +L
Sbjct: 899 ATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTG---------ELA 949
Query: 312 GLQVLRTLVQEKGTEVLAVRVVTLLYDLVTEKMFAEEEAELTQEMSPEKLQQYRQVHLLP 371
GL+ QEK +L +L+ +K+ + E E + ++ + L
Sbjct: 950 GLRQQIIATQEK---------ASLDKELMAQKL-VQAEREAQASLREQRAAHEEDLQRLQ 999
Query: 372 GLWEQGWCEITAHLLALPEHDAREKVLQTLGVLLTTCRDRYRQD---PQLGRTLASLQAE 428
E W E+ A L RE+ + L L ++ ++ Q R L AE
Sbjct: 1000 REKEAAWRELEAERAQLQSQLQREQ--EELLARLEAEKEELSEEIAALQQERDEGLLLAE 1057
Query: 429 YQVLASLELQDGEDEGYFQELLGSVNSL 456
+ +L L++ E ++L+G+ +SL
Sbjct: 1058 SEKQQALSLKESEKTALSEKLMGTRHSL 1085
>gi|4758648 kinesin family member 5B [Homo sapiens]
Length = 963
Score = 36.6 bits (83), Expect = 0.049
Identities = 55/298 (18%), Positives = 125/298 (41%), Gaps = 33/298 (11%)
Query: 92 RLNLQTGEREAKLQYEDKFRNNLKGKRLDINTNTYTSQDLKSALAKFKEGAEMESSK--- 148
+L Q +++ ++ + + LK + LD ++L ++ + ++ + E ++
Sbjct: 427 KLYKQLDDKDEEINQQSQLVEKLKTQMLD-------QEELLASTRRDQDNMQAELNRLQA 479
Query: 149 EDKARQAEVKRLFRPIEELKKDFDELNVVIETDMQIMVRLINKFNSSSSSLEEKIAALFD 208
E+ A + EVK + + +EEL ++D+ + +E + L ++ N S++L A L
Sbjct: 480 ENDASKEEVKEVLQALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSATLASIDAELQK 539
Query: 209 L-EYYVHQMDNAQDL-------LSFGGLQVVINGLNSTEPLVKEYAAFVLGAAFSSNPKV 260
L E HQ A ++ L+ G+ V N + E F + + S K
Sbjct: 540 LKEMTNHQKKRAAEMMASLLKDLAEIGIAVGNNDVKQPEGTGMIDEEFTVARLYISKMKS 599
Query: 261 QVEAIEGGALQKLLVILATEQPLTAKKKVLFALCSLLRHFPYAQRQFLKLGGLQVLRTLV 320
+V+ + Q + + + +K L A C L +Q + + L+ +
Sbjct: 600 EVKTMVKRCKQLESTQTESNKKMEENEKEL-AACQL----RISQHEAKIKSLTEYLQNVE 654
Query: 321 QEK----------GTEVLAVRVVTLLYDLVTEKMFAEEEAELTQEMSPEKLQQYRQVH 368
Q+K E++ +R ++++ E + + A ++ +++Q +R+ H
Sbjct: 655 QKKRQLEESVDALSEELVQLRAQEKVHEMEKEHLNKVQTANEVKQAVEQQIQSHRETH 712
>gi|170650672 Leber congenital amaurosis 5 [Homo sapiens]
Length = 697
Score = 36.6 bits (83), Expect = 0.049
Identities = 30/130 (23%), Positives = 63/130 (48%), Gaps = 11/130 (8%)
Query: 48 TKETERKETKAEEELDAEVLEVFHPTHEWQALQPGQAVPAGSHVRLNLQTGEREAKLQYE 107
++E ER K ++ ++E+ + + + + +P + L + E L+ +
Sbjct: 178 SQEKERATEKRVKDTESELFRTKFSLQKLKEISEARHLPERDDLAKKLVSAE----LKLD 233
Query: 108 DKFRNNLK-GKRLDINTNTYTSQDLKSALAKFKEGAEMESSKEDKARQAEVKRLFRPIEE 166
D R + K L+++TN++ Q LA+ K E+ E+K Q EV+RL+ ++E
Sbjct: 234 DTERRIKELSKNLELSTNSFQRQ----LLAERKRA--YEAHDENKVLQKEVQRLYHKLKE 287
Query: 167 LKKDFDELNV 176
+++ D N+
Sbjct: 288 KERELDIKNI 297
>gi|170650670 Leber congenital amaurosis 5 [Homo sapiens]
Length = 697
Score = 36.6 bits (83), Expect = 0.049
Identities = 30/130 (23%), Positives = 63/130 (48%), Gaps = 11/130 (8%)
Query: 48 TKETERKETKAEEELDAEVLEVFHPTHEWQALQPGQAVPAGSHVRLNLQTGEREAKLQYE 107
++E ER K ++ ++E+ + + + + +P + L + E L+ +
Sbjct: 178 SQEKERATEKRVKDTESELFRTKFSLQKLKEISEARHLPERDDLAKKLVSAE----LKLD 233
Query: 108 DKFRNNLK-GKRLDINTNTYTSQDLKSALAKFKEGAEMESSKEDKARQAEVKRLFRPIEE 166
D R + K L+++TN++ Q LA+ K E+ E+K Q EV+RL+ ++E
Sbjct: 234 DTERRIKELSKNLELSTNSFQRQ----LLAERKRA--YEAHDENKVLQKEVQRLYHKLKE 287
Query: 167 LKKDFDELNV 176
+++ D N+
Sbjct: 288 KERELDIKNI 297
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 36.2 bits (82), Expect = 0.064
Identities = 99/447 (22%), Positives = 166/447 (37%), Gaps = 67/447 (14%)
Query: 31 SHQNLKEFALTNPEKSSTKETERKETKAEEELDAEVLEVFHPTHEWQALQPGQAVPAGSH 90
S + KE A E TK+ K +EL+ +++ + ++ Q V A S
Sbjct: 843 SAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQL-----QVQAESE 897
Query: 91 VRLNLQTGEREAKLQYEDKFRNNLKGKRLDINTNTYTSQDLKSALAKFKEGAEMESSKED 150
NL E + KF+ L+ K ++ +++ + L K E E S
Sbjct: 898 ---NLLDAEERCDQLIKAKFQ--LEAKIKEVTERAEDEEEINAELTAKKRKLEDECS--- 949
Query: 151 KARQAEVKRLFRPIEELKKDFDELNVV---IETDMQIMVRLINKFNSSSSSLEEKIAALF 207
ELKKD D+L + +E + + S L+E IA L
Sbjct: 950 ---------------ELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKL- 993
Query: 208 DLEYYVHQMDNAQDLLSFGGLQVVINGLNSTEPLVKEYAAFVLGAAFSSNPKVQVE---- 263
E Q + Q L + +N LN T+ +++ L ++ K++V+
Sbjct: 994 TREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVE-DLESSLEQEKKLRVDLERN 1052
Query: 264 --AIEGG---ALQKLLVILATEQPLTAK-KKVLFALCSLLRHFPYAQR---QFLKLGGLQ 314
+EG A + +L + +Q L + KK F C L Q QF K ++
Sbjct: 1053 KRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQK--KIK 1110
Query: 315 VLRTLVQEKGTEVLAVRVVTLLYDLVTEKM---FAEEEAELTQEMSPEKLQQYRQVHLLP 371
L+ ++E E+ A R TEK +A E EL++ + Q+ L
Sbjct: 1111 ELQARIEELEEEIEAERATR----AKTEKQRSDYARELEELSERLEEAGGVTSTQIELNK 1166
Query: 372 GLWEQGWCEITAHLLALPEHDAREKVLQTLGVLLTTCRDRYRQDPQLGRTLASLQAEYQV 431
+ A L L D E LQ ++ + +LG + +LQ +V
Sbjct: 1167 --------KREAEFLKL-RRDLEEATLQHEAMVAALRKKHADSVAELGEQIDNLQ---RV 1214
Query: 432 LASLELQDGEDEGYFQELLGSVNSLLK 458
LE + E + +L S+ S+ K
Sbjct: 1215 KQKLEKEKSEFKLEIDDLSSSMESVSK 1241
>gi|7705415 hook homolog 1 [Homo sapiens]
Length = 728
Score = 35.8 bits (81), Expect = 0.084
Identities = 45/195 (23%), Positives = 91/195 (46%), Gaps = 12/195 (6%)
Query: 36 KEFALTNPEKSSTKETERKETKAEEELDAEVL-----EVF-HPTHEWQALQPGQAVPAGS 89
+E + ++ +T+ TK+ E L AE++ EVF HE + L+ Q
Sbjct: 428 EELRCSQVQQDHLNQTDASATKSYENLAAEIMPVEYREVFIRLQHENKMLRLQQEGSENE 487
Query: 90 HVRLNLQTGEREAKLQYEDKFRNNLKGKRLDINTNTYTSQDLKSALAKFKEGAEMESSKE 149
+ + E++ + E + L +R I +DL+ +L + +E ESS +
Sbjct: 488 RIEELQEQLEQKHRKMNELETEQRLSKER--IRELQQQIEDLQKSLQEQGSKSEGESSSK 545
Query: 150 DKAR-QAEVKRLFRPIEELKKDFDELNVVIETDMQIMVRLINKFNSSSSSLEEKIAALFD 208
K + +A +++L EEL+K EL ++ D+ V+ IN+ ++ +E + A+
Sbjct: 546 LKQKLEAHMEKLTEVHEELQKK-QELIEDLQPDINQNVQKINELEAALQKKDEDMKAM-- 602
Query: 209 LEYYVHQMDNAQDLL 223
E Y ++ A++++
Sbjct: 603 EERYKMYLEKARNVI 617
>gi|29540566 armadillo repeat containing, X-linked 3 [Homo sapiens]
Length = 379
Score = 35.4 bits (80), Expect = 0.11
Identities = 31/110 (28%), Positives = 52/110 (47%), Gaps = 5/110 (4%)
Query: 141 GAEMESSKEDKARQAEVKRLFRPIEELKKDFDELNVVIETDMQIMVRLINKFNSSSSSLE 200
G E + +AR A R R +++ + V+ ++Q ++ L+ + + LE
Sbjct: 83 GTEAGTRARARAR-ARATRARRAVQKRASPNSDDTVLSPQELQKVLCLV-EMSEKPYILE 140
Query: 201 EKIAALFDLEYYVHQMDNAQDLLSFGGLQVVINGLNSTEPLVKEYAAFVL 250
+ AL + Y D +DL GGL +V LN+ +P+VKE A VL
Sbjct: 141 AALIALGNNAAYAFNRDIIRDL---GGLPIVAKILNTRDPIVKEKALIVL 187
>gi|29540564 armadillo repeat containing, X-linked 3 [Homo sapiens]
Length = 379
Score = 35.4 bits (80), Expect = 0.11
Identities = 31/110 (28%), Positives = 52/110 (47%), Gaps = 5/110 (4%)
Query: 141 GAEMESSKEDKARQAEVKRLFRPIEELKKDFDELNVVIETDMQIMVRLINKFNSSSSSLE 200
G E + +AR A R R +++ + V+ ++Q ++ L+ + + LE
Sbjct: 83 GTEAGTRARARAR-ARATRARRAVQKRASPNSDDTVLSPQELQKVLCLV-EMSEKPYILE 140
Query: 201 EKIAALFDLEYYVHQMDNAQDLLSFGGLQVVINGLNSTEPLVKEYAAFVL 250
+ AL + Y D +DL GGL +V LN+ +P+VKE A VL
Sbjct: 141 AALIALGNNAAYAFNRDIIRDL---GGLPIVAKILNTRDPIVKEKALIVL 187
>gi|7705274 armadillo repeat containing, X-linked 3 [Homo sapiens]
Length = 379
Score = 35.4 bits (80), Expect = 0.11
Identities = 31/110 (28%), Positives = 52/110 (47%), Gaps = 5/110 (4%)
Query: 141 GAEMESSKEDKARQAEVKRLFRPIEELKKDFDELNVVIETDMQIMVRLINKFNSSSSSLE 200
G E + +AR A R R +++ + V+ ++Q ++ L+ + + LE
Sbjct: 83 GTEAGTRARARAR-ARATRARRAVQKRASPNSDDTVLSPQELQKVLCLV-EMSEKPYILE 140
Query: 201 EKIAALFDLEYYVHQMDNAQDLLSFGGLQVVINGLNSTEPLVKEYAAFVL 250
+ AL + Y D +DL GGL +V LN+ +P+VKE A VL
Sbjct: 141 AALIALGNNAAYAFNRDIIRDL---GGLPIVAKILNTRDPIVKEKALIVL 187
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 34.7 bits (78), Expect = 0.19
Identities = 43/189 (22%), Positives = 73/189 (38%), Gaps = 25/189 (13%)
Query: 37 EFALTNPEKSSTKETERKETKAEEELDAEVLEVFHPTHEWQALQPGQAVPAGS------- 89
E LT EK TE K EE+ A + T E ++LQ
Sbjct: 962 ELTLTKVEKEK-HATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDK 1020
Query: 90 -------HVRLNLQTGEREAKLQYEDKFRNNLKGKRLDINTNTYTSQDLKSALAKFKEGA 142
+ +L QT + E L+ E K R +L+ + + + SQ+ L K+
Sbjct: 1021 VNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQI 1080
Query: 143 EME-SSKEDKARQAEVK---------RLFRPIEELKKDFDELNVVIETDMQIMVRLINKF 192
E + KE + Q + K + + I+EL+ +EL IE + + ++ +
Sbjct: 1081 EEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQR 1140
Query: 193 NSSSSSLEE 201
+ + LEE
Sbjct: 1141 SDLARELEE 1149
>gi|118600973 RNA binding motif protein, X-linked 2 [Homo sapiens]
Length = 322
Score = 34.7 bits (78), Expect = 0.19
Identities = 29/120 (24%), Positives = 57/120 (47%), Gaps = 12/120 (10%)
Query: 43 PEKSSTKETERKETKAEEELDAEVLEVFHPTHEWQALQPGQAVPAGSHVRLNLQTGEREA 102
P K K+ + K+ K +E+ A+ E QA QP + P V+ TG ++
Sbjct: 154 PTKKHKKDKKEKKKKKKEKEKAD--------REVQAEQPSSSSPRRKTVKEKDDTGPKKH 205
Query: 103 KLQYEDKFRNN--LKGKRLDINTNTYT--SQDLKSALAKFKEGAEMESSKEDKARQAEVK 158
+ ++ + + +G++L + Y+ ++DL+ L K K E +SS +AR+ + +
Sbjct: 206 SSKNSERAQKSEPREGQKLPKSRTAYSGGAEDLERELKKEKPKHEHKSSSRREAREEKTR 265
>gi|68299795 chromodomain helicase DNA binding protein 1 [Homo
sapiens]
Length = 1710
Score = 34.7 bits (78), Expect = 0.19
Identities = 31/147 (21%), Positives = 60/147 (40%), Gaps = 12/147 (8%)
Query: 46 SSTKETERKETKAEEELDAEVLEVFHPTHEWQALQPGQAVPAGSHVRLNLQTGER---EA 102
+S E + ++ ++ +EV H +WQ G +GS + + E
Sbjct: 119 NSGSEEDSSSSEDSDDSSSEVKRKKHKDEDWQMSGSGSPSQSGSDSESEEEREKSSCDET 178
Query: 103 KLQYEDKFRNNLKGKRLDINTNTYTSQDLKSALAKFKEGAEMESSKED-------KARQA 155
+ YE K N +K ++ + + + + + + +E + +ED RQA
Sbjct: 179 ESDYEPK--NKVKSRKPQNRSKSKNGKKILGQKKRQIDSSEEDDDEEDYDNDKRSSRRQA 236
Query: 156 EVKRLFRPIEELKKDFDELNVVIETDM 182
V ++ EE+K D D+L V D+
Sbjct: 237 TVNVSYKEDEEMKTDSDDLLEVCGEDV 263
>gi|29294627 PTPRF interacting protein binding protein 1 isoform 1
[Homo sapiens]
Length = 1005
Score = 34.3 bits (77), Expect = 0.24
Identities = 46/196 (23%), Positives = 86/196 (43%), Gaps = 39/196 (19%)
Query: 49 KETERKETKAEEELDAEVLEVFHPTHEWQALQPGQAVPAGSHVRLNLQTGEREAKLQYED 108
+E K EE L E+L + E Q L + S+++L L E++ +L YED
Sbjct: 142 EEHREKVNATEEMLQQELLS--RTSLETQKLDLMAEI---SNLKLKLTAVEKD-RLDYED 195
Query: 109 KFRNNLKGKRLDINTNTYTSQDLKSALAKFKEGAEMESSKEDKA--------RQAEVKRL 160
KFR+ +G +IN ++ S ++++ +++S+K++ A +++EVKRL
Sbjct: 196 KFRDT-EGLIQEINDLRLKVSEMDSERLQYEK--KLKSTKDELASLKEQLEEKESEVKRL 252
Query: 161 FRPI---------------EELKKDFDELNVVIETDMQIMVRLINKFNSSSSSLEEKIAA 205
+ E KK E N+ ++ ++ S ++ EEK
Sbjct: 253 QEKLVCKMKGEGVEIVDRDENFKKKLKEKNIEVQ-------KMKKAVESLMAANEEKDRK 305
Query: 206 LFDLEYYVHQMDNAQD 221
+ DL +++ QD
Sbjct: 306 IEDLRQCLNRYKKMQD 321
>gi|4758650 kinesin family member 5C [Homo sapiens]
Length = 957
Score = 33.9 bits (76), Expect = 0.32
Identities = 43/215 (20%), Positives = 95/215 (44%), Gaps = 22/215 (10%)
Query: 96 QTGEREAKLQYEDKFRNNLKGKRLDINTNTYTSQDLKSALAKFKEGAEMESSK---EDKA 152
Q +++ ++ + + LK + LD +L ++ + E + E ++ E++A
Sbjct: 427 QLDDKDDEINQQSQLAEKLKQQMLD-------QDELLASTRRDYEKIQEELTRLQIENEA 479
Query: 153 RQAEVKRLFRPIEELKKDFDELNVVIETDMQIMVRLINKFNSSSSSLEEKIAALFDL-EY 211
+ EVK + + +EEL ++D+ + +E + +L ++ +++L L L E
Sbjct: 480 AKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQLQEL 539
Query: 212 YVHQMDNAQDLLS-----FGGLQVVINGLNSTEPLVKEYAA----FVLGAAFSSNPKVQV 262
HQ A ++L+ G + +I G N + L F + + S K +V
Sbjct: 540 SNHQKKRATEILNLLLKDLGEIGGII-GTNDVKTLADVNGVIEEEFTMARLYISKMKSEV 598
Query: 263 EAIEGGALQKLLVILATEQPLTAKKKVLFALCSLL 297
+++ + Q + + + + A ++ L A C LL
Sbjct: 599 KSLVNRSKQLESAQMDSNRKMNASEREL-AACQLL 632
Score = 33.9 bits (76), Expect = 0.32
Identities = 42/171 (24%), Positives = 74/171 (43%), Gaps = 18/171 (10%)
Query: 45 KSSTKETERKETKAEEELDAEVLEVFHPTHEWQALQPGQAVPAGSHVRLNLQTG-----E 99
+S+ ++ RK +E EL A ++ HE + + R L+ E
Sbjct: 609 ESAQMDSNRKMNASERELAA--CQLLISQHEAKIKSLTDYMQNMEQKRRQLEESQDSLSE 666
Query: 100 REAKLQYEDKFRN-NLKGKRLDINTNTYTSQDLKSALAKFKEGAEMESSKEDKARQAEVK 158
AKL+ ++K + + K + T ++++K AL + +MES +E A Q ++
Sbjct: 667 ELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQ-----QMESHRE--AHQKQLS 719
Query: 159 RLFRPIEELKKDFDE---LNVVIETDMQIMVRLINKFNSSSSSLEEKIAAL 206
RL IEE +K DE LN ++ + + + NK E K+ L
Sbjct: 720 RLRDEIEEKQKIIDEIRDLNQKLQLEQEKLSSDYNKLKIEDQEREMKLEKL 770
>gi|41281683 disabled homolog 2 interacting protein isoform 2 [Homo
sapiens]
Length = 1065
Score = 33.9 bits (76), Expect = 0.32
Identities = 30/103 (29%), Positives = 49/103 (47%), Gaps = 4/103 (3%)
Query: 136 AKFKEGAE-MESSKEDKARQAE--VKRLFRPIEELKKDFDELNVVIETDMQIMVRLINKF 192
A+ +EG E + +EDK Q + + RL EELKKD E+ +++ +I+ +
Sbjct: 955 ARLEEGEERLRRQQEDKDIQMKGIISRLMSVEEELKKDHAEMQAAVDSKQKIIDAQEKRI 1014
Query: 193 NSSSSSLEEKIAALFDL-EYYVHQMDNAQDLLSFGGLQVVING 234
S ++ ++AL L E Y Q N + LQ+ NG
Sbjct: 1015 ASLDAANARLMSALTQLKERYSMQARNGISPTNPTKLQITENG 1057
>gi|211059433 coiled-coil domain containing 79 [Homo sapiens]
Length = 727
Score = 33.9 bits (76), Expect = 0.32
Identities = 34/144 (23%), Positives = 60/144 (41%), Gaps = 5/144 (3%)
Query: 178 IETDMQIMVRLINKFNSSSSSLEEKIAALFDLEYYVHQMDNAQDLL-SFGGLQVVINGLN 236
++TD+ +++ + ++ S +E AL + Q NA GGL V N
Sbjct: 12 MKTDLNLLLECLKYQMDNAFSQKE---ALVTIHSICQQNSNASVYFREIGGLMFVKNLAK 68
Query: 237 STE-PLVKEYAAFVLGAAFSSNPKVQVEAIEGGALQKLLVILATEQPLTAKKKVLFALCS 295
S+E +VKE A + LGA N Q + L L+ + + K+ ++ +
Sbjct: 69 SSEHSMVKEAALYTLGAIAEKNVYCQQTLCTSELFEDLTWFLSNDSNINLKRMSVYVILV 128
Query: 296 LLRHFPYAQRQFLKLGGLQVLRTL 319
L+ + Q + G + VL L
Sbjct: 129 LVSNNRTGQTLVRETGCITVLSRL 152
>gi|148839339 nexilin (F actin binding protein) [Homo sapiens]
Length = 675
Score = 33.9 bits (76), Expect = 0.32
Identities = 42/171 (24%), Positives = 77/171 (45%), Gaps = 24/171 (14%)
Query: 44 EKSSTKETERKETKAEEELDAEVLEVFHPTHEWQALQPGQAVPAGSHVRLNLQTG----- 98
++ S KE + ++E+++E + ++L PG+ + Q
Sbjct: 215 QRPSLKEAKCLSLVMDDEIESEAKK--------ESLSPGKLKLTFEELERQRQENRKKQA 266
Query: 99 EREAKLQYEDKFRNNLKGKRLDINTNTYTSQDLKSALAKFKEGA------EMESSK-EDK 151
E EA+ + E++ R + +R +N + +QD ++ G EME + ED+
Sbjct: 267 EEEARKRLEEEKRAFEEARRQMVNEDE-ENQDTAKIFKGYRPGKLKLSFEEMERQRREDE 325
Query: 152 ARQAEVKRLFRPIEELKKDFDEL--NVVIETDMQIMVRLINKFNSSSSSLE 200
R+AE + R IEE KK F E N+V++ D M + I++ + LE
Sbjct: 326 KRKAE-EEARRRIEEEKKAFAEARRNMVVDDDSPEMYKTISQEFLTPGKLE 375
>gi|37588869 ring finger protein 123 [Homo sapiens]
Length = 1314
Score = 33.5 bits (75), Expect = 0.42
Identities = 36/141 (25%), Positives = 63/141 (44%), Gaps = 9/141 (6%)
Query: 260 VQVEAIEGGALQKLLVILATEQPLTAKKKVLFALCSLLRHF-PYAQRQFLKLGGLQVLRT 318
V+++ +EG L K +++ L + VL L + HF P ++ +L L
Sbjct: 288 VELDPVEGRLLDKE----SSKWRLRGQPTVLLTLAHIFHHFAPLLRKVYLVEAVLMSFLL 343
Query: 319 LVQEKGTEVLAVRVVTLLYDLVTEKMFAEEEAELTQEMSPEKLQQYRQVHLLPGLWEQ-G 377
+ EKGT A VV + DL+ M E + +++ L+ YR ++P L Q
Sbjct: 344 GIVEKGTPTQAQSVVHQVLDLLWLFMEDYEVQDCLKQLMMSLLRLYRFSPIVPDLGLQIH 403
Query: 378 WCEITAHLLALPEHDAREKVL 398
+ +T +A+ H+ K L
Sbjct: 404 YLRLT---IAILRHEKSRKFL 421
>gi|150170718 zinc finger protein 292 [Homo sapiens]
Length = 2723
Score = 33.5 bits (75), Expect = 0.42
Identities = 32/176 (18%), Positives = 71/176 (40%), Gaps = 10/176 (5%)
Query: 39 ALTNPEKSSTKETERKETKAEEELDAEVLEVFHPTHEWQALQPGQAVPAGSHVRLNLQTG 98
ALTN + K K+ K E++ V + + +P + V G +Q
Sbjct: 2071 ALTNTQTKGRKIRRHKKEKEEKKRKKPVSQSLEFPTRYSPYRPYRCVHQGCFAAFTIQ-- 2128
Query: 99 EREAKLQYEDKFRNNLKGKRLDINTNTYTSQDLKSALAKFKEGAEMESSKEDKARQAEVK 158
+ L Y+ +++L ++ + ++ + K ++ KE + + ++
Sbjct: 2129 -QNLILHYQAVHKSDLPAFSAEVEEESEAGKESEETETK-------QTLKEFRCQVSDCS 2180
Query: 159 RLFRPIEELKKDFDELNVVIETDMQIMVRLINKFNSSSSSLEEKIAALFDLEYYVH 214
R+F+ I L + + +L+ + +++ M ++ LE K + L Y VH
Sbjct: 2181 RIFQAITGLIQHYMKLHEMTPEEIESMTASVDVGKFPCDQLECKSSFTTYLNYVVH 2236
>gi|7662162 ALEX2 protein [Homo sapiens]
Length = 632
Score = 33.5 bits (75), Expect = 0.42
Identities = 26/110 (23%), Positives = 52/110 (47%), Gaps = 6/110 (5%)
Query: 143 EMESSKEDKARQAEVKRLFRPIEELKKDFD-ELNVVIET-DMQIMVRLINKFNSSSSSLE 200
+ ES + + R RP+ K+ F E++ ++ D++ ++ L+ K S ++
Sbjct: 347 DTESDSDSEPETQRRGRGRRPVAMQKRPFPYEIDEILGVRDLRKVLALLQK--SDDPFIQ 404
Query: 201 EKIAALFDLEYYVHQMDNAQDLLSFGGLQVVINGLNSTEPLVKEYAAFVL 250
+ AL L + N + + GGL ++ N +N T+P +KE A +
Sbjct: 405 Q--VALLTLSNNANYSCNQETIRKLGGLPIIANMINKTDPHIKEKALMAM 452
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.132 0.365
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,791,319
Number of Sequences: 37866
Number of extensions: 658114
Number of successful extensions: 3123
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 92
Number of HSP's that attempted gapping in prelim test: 3014
Number of HSP's gapped (non-prelim): 210
length of query: 461
length of database: 18,247,518
effective HSP length: 106
effective length of query: 355
effective length of database: 14,233,722
effective search space: 5052971310
effective search space used: 5052971310
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.