Guide to the Human Genome
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Search of human proteins with 11968009

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|11968009 SIL1 protein precursor [Homo sapiens]
         (461 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|11968009 SIL1 protein precursor [Homo sapiens]                     898   0.0  
gi|83641896 SIL1 protein precursor [Homo sapiens]                     898   0.0  
gi|194294548 hsp70-interacting protein [Homo sapiens]                  54   3e-07
gi|112363070 hsp70-interacting protein [Homo sapiens]                  54   3e-07
gi|19924131 RAD50 homolog isoform 2 [Homo sapiens]                     42   0.002
gi|19924129 RAD50 homolog isoform 1 [Homo sapiens]                     42   0.002
gi|226958575 RAS protein activator like 2 isoform 2 [Homo sapiens]     40   0.003
gi|4758808 RAS protein activator like 2 isoform 1 [Homo sapiens]       40   0.003
gi|6912678 sperm associated antigen 6 isoform 1 [Homo sapiens]         40   0.004
gi|27262641 sperm associated antigen 6 isoform 2 [Homo sapiens]        40   0.004
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]                37   0.038
gi|4758648 kinesin family member 5B [Homo sapiens]                     37   0.049
gi|170650672 Leber congenital amaurosis 5 [Homo sapiens]               37   0.049
gi|170650670 Leber congenital amaurosis 5 [Homo sapiens]               37   0.049
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H...    36   0.064
gi|7705415 hook homolog 1 [Homo sapiens]                               36   0.084
gi|29540566 armadillo repeat containing, X-linked 3 [Homo sapiens]     35   0.11 
gi|29540564 armadillo repeat containing, X-linked 3 [Homo sapiens]     35   0.11 
gi|7705274 armadillo repeat containing, X-linked 3 [Homo sapiens]      35   0.11 
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo...    35   0.19 
gi|118600973 RNA binding motif protein, X-linked 2 [Homo sapiens]      35   0.19 
gi|68299795 chromodomain helicase DNA binding protein 1 [Homo sa...    35   0.19 
gi|29294627 PTPRF interacting protein binding protein 1 isoform ...    34   0.24 
gi|4758650 kinesin family member 5C [Homo sapiens]                     34   0.32 
gi|41281683 disabled homolog 2 interacting protein isoform 2 [Ho...    34   0.32 
gi|211059433 coiled-coil domain containing 79 [Homo sapiens]           34   0.32 
gi|148839339 nexilin (F actin binding protein) [Homo sapiens]          34   0.32 
gi|37588869 ring finger protein 123 [Homo sapiens]                     33   0.42 
gi|150170718 zinc finger protein 292 [Homo sapiens]                    33   0.42 
gi|7662162 ALEX2 protein [Homo sapiens]                                33   0.42 

>gi|11968009 SIL1 protein precursor [Homo sapiens]
          Length = 461

 Score =  898 bits (2321), Expect = 0.0
 Identities = 461/461 (100%), Positives = 461/461 (100%)

Query: 1   MAPQSLPSSRMAPLGMLLGLLMAACFTFCLSHQNLKEFALTNPEKSSTKETERKETKAEE 60
           MAPQSLPSSRMAPLGMLLGLLMAACFTFCLSHQNLKEFALTNPEKSSTKETERKETKAEE
Sbjct: 1   MAPQSLPSSRMAPLGMLLGLLMAACFTFCLSHQNLKEFALTNPEKSSTKETERKETKAEE 60

Query: 61  ELDAEVLEVFHPTHEWQALQPGQAVPAGSHVRLNLQTGEREAKLQYEDKFRNNLKGKRLD 120
           ELDAEVLEVFHPTHEWQALQPGQAVPAGSHVRLNLQTGEREAKLQYEDKFRNNLKGKRLD
Sbjct: 61  ELDAEVLEVFHPTHEWQALQPGQAVPAGSHVRLNLQTGEREAKLQYEDKFRNNLKGKRLD 120

Query: 121 INTNTYTSQDLKSALAKFKEGAEMESSKEDKARQAEVKRLFRPIEELKKDFDELNVVIET 180
           INTNTYTSQDLKSALAKFKEGAEMESSKEDKARQAEVKRLFRPIEELKKDFDELNVVIET
Sbjct: 121 INTNTYTSQDLKSALAKFKEGAEMESSKEDKARQAEVKRLFRPIEELKKDFDELNVVIET 180

Query: 181 DMQIMVRLINKFNSSSSSLEEKIAALFDLEYYVHQMDNAQDLLSFGGLQVVINGLNSTEP 240
           DMQIMVRLINKFNSSSSSLEEKIAALFDLEYYVHQMDNAQDLLSFGGLQVVINGLNSTEP
Sbjct: 181 DMQIMVRLINKFNSSSSSLEEKIAALFDLEYYVHQMDNAQDLLSFGGLQVVINGLNSTEP 240

Query: 241 LVKEYAAFVLGAAFSSNPKVQVEAIEGGALQKLLVILATEQPLTAKKKVLFALCSLLRHF 300
           LVKEYAAFVLGAAFSSNPKVQVEAIEGGALQKLLVILATEQPLTAKKKVLFALCSLLRHF
Sbjct: 241 LVKEYAAFVLGAAFSSNPKVQVEAIEGGALQKLLVILATEQPLTAKKKVLFALCSLLRHF 300

Query: 301 PYAQRQFLKLGGLQVLRTLVQEKGTEVLAVRVVTLLYDLVTEKMFAEEEAELTQEMSPEK 360
           PYAQRQFLKLGGLQVLRTLVQEKGTEVLAVRVVTLLYDLVTEKMFAEEEAELTQEMSPEK
Sbjct: 301 PYAQRQFLKLGGLQVLRTLVQEKGTEVLAVRVVTLLYDLVTEKMFAEEEAELTQEMSPEK 360

Query: 361 LQQYRQVHLLPGLWEQGWCEITAHLLALPEHDAREKVLQTLGVLLTTCRDRYRQDPQLGR 420
           LQQYRQVHLLPGLWEQGWCEITAHLLALPEHDAREKVLQTLGVLLTTCRDRYRQDPQLGR
Sbjct: 361 LQQYRQVHLLPGLWEQGWCEITAHLLALPEHDAREKVLQTLGVLLTTCRDRYRQDPQLGR 420

Query: 421 TLASLQAEYQVLASLELQDGEDEGYFQELLGSVNSLLKELR 461
           TLASLQAEYQVLASLELQDGEDEGYFQELLGSVNSLLKELR
Sbjct: 421 TLASLQAEYQVLASLELQDGEDEGYFQELLGSVNSLLKELR 461


>gi|83641896 SIL1 protein precursor [Homo sapiens]
          Length = 461

 Score =  898 bits (2321), Expect = 0.0
 Identities = 461/461 (100%), Positives = 461/461 (100%)

Query: 1   MAPQSLPSSRMAPLGMLLGLLMAACFTFCLSHQNLKEFALTNPEKSSTKETERKETKAEE 60
           MAPQSLPSSRMAPLGMLLGLLMAACFTFCLSHQNLKEFALTNPEKSSTKETERKETKAEE
Sbjct: 1   MAPQSLPSSRMAPLGMLLGLLMAACFTFCLSHQNLKEFALTNPEKSSTKETERKETKAEE 60

Query: 61  ELDAEVLEVFHPTHEWQALQPGQAVPAGSHVRLNLQTGEREAKLQYEDKFRNNLKGKRLD 120
           ELDAEVLEVFHPTHEWQALQPGQAVPAGSHVRLNLQTGEREAKLQYEDKFRNNLKGKRLD
Sbjct: 61  ELDAEVLEVFHPTHEWQALQPGQAVPAGSHVRLNLQTGEREAKLQYEDKFRNNLKGKRLD 120

Query: 121 INTNTYTSQDLKSALAKFKEGAEMESSKEDKARQAEVKRLFRPIEELKKDFDELNVVIET 180
           INTNTYTSQDLKSALAKFKEGAEMESSKEDKARQAEVKRLFRPIEELKKDFDELNVVIET
Sbjct: 121 INTNTYTSQDLKSALAKFKEGAEMESSKEDKARQAEVKRLFRPIEELKKDFDELNVVIET 180

Query: 181 DMQIMVRLINKFNSSSSSLEEKIAALFDLEYYVHQMDNAQDLLSFGGLQVVINGLNSTEP 240
           DMQIMVRLINKFNSSSSSLEEKIAALFDLEYYVHQMDNAQDLLSFGGLQVVINGLNSTEP
Sbjct: 181 DMQIMVRLINKFNSSSSSLEEKIAALFDLEYYVHQMDNAQDLLSFGGLQVVINGLNSTEP 240

Query: 241 LVKEYAAFVLGAAFSSNPKVQVEAIEGGALQKLLVILATEQPLTAKKKVLFALCSLLRHF 300
           LVKEYAAFVLGAAFSSNPKVQVEAIEGGALQKLLVILATEQPLTAKKKVLFALCSLLRHF
Sbjct: 241 LVKEYAAFVLGAAFSSNPKVQVEAIEGGALQKLLVILATEQPLTAKKKVLFALCSLLRHF 300

Query: 301 PYAQRQFLKLGGLQVLRTLVQEKGTEVLAVRVVTLLYDLVTEKMFAEEEAELTQEMSPEK 360
           PYAQRQFLKLGGLQVLRTLVQEKGTEVLAVRVVTLLYDLVTEKMFAEEEAELTQEMSPEK
Sbjct: 301 PYAQRQFLKLGGLQVLRTLVQEKGTEVLAVRVVTLLYDLVTEKMFAEEEAELTQEMSPEK 360

Query: 361 LQQYRQVHLLPGLWEQGWCEITAHLLALPEHDAREKVLQTLGVLLTTCRDRYRQDPQLGR 420
           LQQYRQVHLLPGLWEQGWCEITAHLLALPEHDAREKVLQTLGVLLTTCRDRYRQDPQLGR
Sbjct: 361 LQQYRQVHLLPGLWEQGWCEITAHLLALPEHDAREKVLQTLGVLLTTCRDRYRQDPQLGR 420

Query: 421 TLASLQAEYQVLASLELQDGEDEGYFQELLGSVNSLLKELR 461
           TLASLQAEYQVLASLELQDGEDEGYFQELLGSVNSLLKELR
Sbjct: 421 TLASLQAEYQVLASLELQDGEDEGYFQELLGSVNSLLKELR 461


>gi|194294548 hsp70-interacting protein [Homo sapiens]
          Length = 359

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 42/142 (29%), Positives = 71/142 (50%), Gaps = 2/142 (1%)

Query: 200 EEKIAALFDLEYYVHQMDNAQDLLSFGGLQVVING-LNSTEPLVKEYAAFVLGAAFSSNP 258
           +E+  AL  L      MDNA D     G+ +++   L +    ++  AA ++G    +  
Sbjct: 118 QEREGALELLADLCENMDNAADFCQLSGMHLLVGRYLEAGAAGLRWRAAQLIGTCSQNVA 177

Query: 259 KVQVEAIEGGALQKLLVILATEQPLTAKKKVLFALCSLLRHFPYAQRQFLKLGGLQVLRT 318
            +Q + +  GAL+KLL +L  +   T + K LFA+  L+R       QFL+L G  VL  
Sbjct: 178 AIQEQVLGLGALRKLLRLLDRDACDTVRVKALFAISCLVREQEAGLLQFLRLDGFSVLMR 237

Query: 319 LVQEKGTEVLAVRVVTLLYDLV 340
            +Q++  + L V+   LL +L+
Sbjct: 238 AMQQQ-VQKLKVKSAFLLQNLL 258



 Score = 37.4 bits (85), Expect = 0.029
 Identities = 27/106 (25%), Positives = 49/106 (46%), Gaps = 2/106 (1%)

Query: 202 KIAALFDLEYYVHQMD-NAQDLLSFGGLQVVINGLNSTEPLVKEYAAFVLGAAFSSNPKV 260
           ++ ALF +   V + +      L   G  V++  +      +K  +AF+L      +P+ 
Sbjct: 205 RVKALFAISCLVREQEAGLLQFLRLDGFSVLMRAMQQQVQKLKVKSAFLLQNLLVGHPEH 264

Query: 261 QVEAIEGGALQKLLVILATEQPLTAKKKVLFALCSLLRHFPYAQRQ 306
           +      G +Q+L+ ++ TE      + VL ALCSL+  FP   R+
Sbjct: 265 KGTLCSMGMVQQLVALVRTEHS-PFHEHVLGALCSLVTDFPQGVRE 309


>gi|112363070 hsp70-interacting protein [Homo sapiens]
          Length = 359

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 42/142 (29%), Positives = 71/142 (50%), Gaps = 2/142 (1%)

Query: 200 EEKIAALFDLEYYVHQMDNAQDLLSFGGLQVVING-LNSTEPLVKEYAAFVLGAAFSSNP 258
           +E+  AL  L      MDNA D     G+ +++   L +    ++  AA ++G    +  
Sbjct: 118 QEREGALELLADLCENMDNAADFCQLSGMHLLVGRYLEAGAAGLRWRAAQLIGTCSQNVA 177

Query: 259 KVQVEAIEGGALQKLLVILATEQPLTAKKKVLFALCSLLRHFPYAQRQFLKLGGLQVLRT 318
            +Q + +  GAL+KLL +L  +   T + K LFA+  L+R       QFL+L G  VL  
Sbjct: 178 AIQEQVLGLGALRKLLRLLDRDACDTVRVKALFAISCLVREQEAGLLQFLRLDGFSVLMR 237

Query: 319 LVQEKGTEVLAVRVVTLLYDLV 340
            +Q++  + L V+   LL +L+
Sbjct: 238 AMQQQ-VQKLKVKSAFLLQNLL 258



 Score = 37.4 bits (85), Expect = 0.029
 Identities = 27/106 (25%), Positives = 49/106 (46%), Gaps = 2/106 (1%)

Query: 202 KIAALFDLEYYVHQMD-NAQDLLSFGGLQVVINGLNSTEPLVKEYAAFVLGAAFSSNPKV 260
           ++ ALF +   V + +      L   G  V++  +      +K  +AF+L      +P+ 
Sbjct: 205 RVKALFAISCLVREQEAGLLQFLRLDGFSVLMRAMQQQVQKLKVKSAFLLQNLLVGHPEH 264

Query: 261 QVEAIEGGALQKLLVILATEQPLTAKKKVLFALCSLLRHFPYAQRQ 306
           +      G +Q+L+ ++ TE      + VL ALCSL+  FP   R+
Sbjct: 265 KGTLCSMGMVQQLVALVRTEHS-PFHEHVLGALCSLVTDFPQGVRE 309


>gi|19924131 RAD50 homolog isoform 2 [Homo sapiens]
          Length = 1173

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 26/105 (24%), Positives = 48/105 (45%), Gaps = 15/105 (14%)

Query: 99  EREAKLQYEDKFRNNLKGKRLDINTNTYTSQDLKSALAKFKEGAEMESSKEDKARQAEVK 158
           +++ ++Q+     N LK ++L I+TN    Q L+    +                  EV+
Sbjct: 716 DQQEQIQHLKSTTNELKSEKLQISTNLQRRQQLEEQTVELS---------------TEVQ 760

Query: 159 RLFRPIEELKKDFDELNVVIETDMQIMVRLINKFNSSSSSLEEKI 203
            L+R I++ K+    L   +E   Q    LINK N+S+   ++K+
Sbjct: 761 SLYREIKDAKEQVSPLETTLEKFQQEKEELINKKNTSNKIAQDKL 805


>gi|19924129 RAD50 homolog isoform 1 [Homo sapiens]
          Length = 1312

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 26/105 (24%), Positives = 48/105 (45%), Gaps = 15/105 (14%)

Query: 99  EREAKLQYEDKFRNNLKGKRLDINTNTYTSQDLKSALAKFKEGAEMESSKEDKARQAEVK 158
           +++ ++Q+     N LK ++L I+TN    Q L+    +                  EV+
Sbjct: 855 DQQEQIQHLKSTTNELKSEKLQISTNLQRRQQLEEQTVELS---------------TEVQ 899

Query: 159 RLFRPIEELKKDFDELNVVIETDMQIMVRLINKFNSSSSSLEEKI 203
            L+R I++ K+    L   +E   Q    LINK N+S+   ++K+
Sbjct: 900 SLYREIKDAKEQVSPLETTLEKFQQEKEELINKKNTSNKIAQDKL 944


>gi|226958575 RAS protein activator like 2 isoform 2 [Homo sapiens]
          Length = 1280

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 60/255 (23%), Positives = 102/255 (40%), Gaps = 28/255 (10%)

Query: 2    APQSLPSSRMAPLGMLLGLLMAACFTFCLSHQNLKEFALTNPEKSSTKET--------ER 53
            AP SLP S        + ++ AA     L  + ++  + +  + SS++E+        +R
Sbjct: 1025 APPSLPHSASLRSTGSMSVVSAA-----LVAEPVQNGSRSRQQSSSSRESPVPKVRAIQR 1079

Query: 54   KETK-AEEELDAEVLEVFHPTHEWQALQPGQAVPAGSHVRLNLQTGEREAKLQYED---K 109
            ++T+  +  +D+  +     T  W  L  GQ          NL   +   K + E    K
Sbjct: 1080 QQTQQVQSPVDSATMSPVERTAAW-VLNNGQYEEDVEETEQNLDEAKHAEKYEQEITKLK 1138

Query: 110  FRNNLKGKRLDINTNTYTSQDLKSALAKFKEGAEMESSKEDKARQAEVK---------RL 160
             R  +  +RL+        Q+ +      +  A +E S+E   RQ E K         RL
Sbjct: 1139 ERLRVSSRRLEEYERRLLVQEQQMQKLLLEYKARLEDSEERLRRQQEEKDSQMKSIISRL 1198

Query: 161  FRPIEELKKDFDELNVVIETDMQIMVRLINKFNSSSSSLEEKIAALFDL-EYYVHQMDNA 219
                EELKKD  E+  VI+   +I+     +  S  S+    ++AL  + E Y  Q+ N 
Sbjct: 1199 MAVEEELKKDHAEMQAVIDAKQKIIDAQEKRIVSLDSANTRLMSALTQVKERYSMQVRNG 1258

Query: 220  QDLLSFGGLQVVING 234
                +   L +  NG
Sbjct: 1259 ISPTNPTKLSITENG 1273


>gi|4758808 RAS protein activator like 2 isoform 1 [Homo sapiens]
          Length = 1139

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 60/255 (23%), Positives = 102/255 (40%), Gaps = 28/255 (10%)

Query: 2    APQSLPSSRMAPLGMLLGLLMAACFTFCLSHQNLKEFALTNPEKSSTKET--------ER 53
            AP SLP S        + ++ AA     L  + ++  + +  + SS++E+        +R
Sbjct: 884  APPSLPHSASLRSTGSMSVVSAA-----LVAEPVQNGSRSRQQSSSSRESPVPKVRAIQR 938

Query: 54   KETK-AEEELDAEVLEVFHPTHEWQALQPGQAVPAGSHVRLNLQTGEREAKLQYED---K 109
            ++T+  +  +D+  +     T  W  L  GQ          NL   +   K + E    K
Sbjct: 939  QQTQQVQSPVDSATMSPVERTAAW-VLNNGQYEEDVEETEQNLDEAKHAEKYEQEITKLK 997

Query: 110  FRNNLKGKRLDINTNTYTSQDLKSALAKFKEGAEMESSKEDKARQAEVK---------RL 160
             R  +  +RL+        Q+ +      +  A +E S+E   RQ E K         RL
Sbjct: 998  ERLRVSSRRLEEYERRLLVQEQQMQKLLLEYKARLEDSEERLRRQQEEKDSQMKSIISRL 1057

Query: 161  FRPIEELKKDFDELNVVIETDMQIMVRLINKFNSSSSSLEEKIAALFDL-EYYVHQMDNA 219
                EELKKD  E+  VI+   +I+     +  S  S+    ++AL  + E Y  Q+ N 
Sbjct: 1058 MAVEEELKKDHAEMQAVIDAKQKIIDAQEKRIVSLDSANTRLMSALTQVKERYSMQVRNG 1117

Query: 220  QDLLSFGGLQVVING 234
                +   L +  NG
Sbjct: 1118 ISPTNPTKLSITENG 1132


>gi|6912678 sperm associated antigen 6 isoform 1 [Homo sapiens]
          Length = 509

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 27/107 (25%), Positives = 48/107 (44%), Gaps = 1/107 (0%)

Query: 214 HQMDNAQDLLSFGGLQVVINGLNSTEPLVKEYAAFVLGAAFSSNPKVQVEAIEGGALQKL 273
           H    AQ ++  G L  ++  L   +P VKE AA+ L      N ++    ++ GA+  L
Sbjct: 113 HSPQLAQAIVDCGALDTLVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAV-PL 171

Query: 274 LVILATEQPLTAKKKVLFALCSLLRHFPYAQRQFLKLGGLQVLRTLV 320
           LV+   E  +  K+    AL  + +H P   +  +  G +  L  ++
Sbjct: 172 LVLCIQEPEIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMI 218



 Score = 34.7 bits (78), Expect = 0.19
 Identities = 27/106 (25%), Positives = 48/106 (45%), Gaps = 1/106 (0%)

Query: 217 DNAQDLLSFGGLQVVINGLNSTEPLVKEYAAFVLGAAFSSNPKVQVEAIEGGALQKLLVI 276
           D A+ ++    L  ++  L       K+ AAFVL A    +P++    ++ GAL  L++ 
Sbjct: 74  DLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQAIVDCGALDTLVIC 133

Query: 277 LATEQPLTAKKKVLFALCSLLRHFPYAQRQFLKLGGLQVLRTLVQE 322
           L    P   K+   +AL  + RH     +  +  G + +L   +QE
Sbjct: 134 LEDFDP-GVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQE 178



 Score = 30.4 bits (67), Expect = 3.5
 Identities = 37/165 (22%), Positives = 69/165 (41%), Gaps = 4/165 (2%)

Query: 168 KKDFDELNVVIETDMQIMVRLINKFNSSSSSLEEKIAALFDLEYYVHQMDNAQDLLSFGG 227
           K   D   +V+E ++  +V    K         +K A+    E   H  + +Q +++ GG
Sbjct: 238 KHSVDLAEMVVEAEIFPVVLTCLK---DKDEYVKKNASTLIREIAKHTPELSQLVVNAGG 294

Query: 228 LQVVINGLNSTEPLVKEYAAFVLGAAFSSNPKVQVEAIEGGALQKLLVILATEQPLTAKK 287
           +  VI+ + S +   +     +LG   + +  + +  I    + +L V L+ E     K 
Sbjct: 295 VAAVIDCIGSCKGNTRLPGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPEDHIKA 354

Query: 288 KVLFALCSLLRHFPYAQRQFLKLGGLQVLRTL-VQEKGTEVLAVR 331
              +AL  + RH P   R       L VL +L +  + +E L V+
Sbjct: 355 AAAWALGQIGRHTPEHARAVAVTNTLPVLLSLYMSTESSEDLQVK 399


>gi|27262641 sperm associated antigen 6 isoform 2 [Homo sapiens]
          Length = 458

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 27/107 (25%), Positives = 48/107 (44%), Gaps = 1/107 (0%)

Query: 214 HQMDNAQDLLSFGGLQVVINGLNSTEPLVKEYAAFVLGAAFSSNPKVQVEAIEGGALQKL 273
           H    AQ ++  G L  ++  L   +P VKE AA+ L      N ++    ++ GA+  L
Sbjct: 113 HSPQLAQAIVDCGALDTLVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAV-PL 171

Query: 274 LVILATEQPLTAKKKVLFALCSLLRHFPYAQRQFLKLGGLQVLRTLV 320
           LV+   E  +  K+    AL  + +H P   +  +  G +  L  ++
Sbjct: 172 LVLCIQEPEIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMI 218



 Score = 34.7 bits (78), Expect = 0.19
 Identities = 27/106 (25%), Positives = 48/106 (45%), Gaps = 1/106 (0%)

Query: 217 DNAQDLLSFGGLQVVINGLNSTEPLVKEYAAFVLGAAFSSNPKVQVEAIEGGALQKLLVI 276
           D A+ ++    L  ++  L       K+ AAFVL A    +P++    ++ GAL  L++ 
Sbjct: 74  DLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQAIVDCGALDTLVIC 133

Query: 277 LATEQPLTAKKKVLFALCSLLRHFPYAQRQFLKLGGLQVLRTLVQE 322
           L    P   K+   +AL  + RH     +  +  G + +L   +QE
Sbjct: 134 LEDFDP-GVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQE 178



 Score = 30.4 bits (67), Expect = 3.5
 Identities = 37/165 (22%), Positives = 69/165 (41%), Gaps = 4/165 (2%)

Query: 168 KKDFDELNVVIETDMQIMVRLINKFNSSSSSLEEKIAALFDLEYYVHQMDNAQDLLSFGG 227
           K   D   +V+E ++  +V    K         +K A+    E   H  + +Q +++ GG
Sbjct: 238 KHSVDLAEMVVEAEIFPVVLTCLK---DKDEYVKKNASTLIREIAKHTPELSQLVVNAGG 294

Query: 228 LQVVINGLNSTEPLVKEYAAFVLGAAFSSNPKVQVEAIEGGALQKLLVILATEQPLTAKK 287
           +  VI+ + S +   +     +LG   + +  + +  I    + +L V L+ E     K 
Sbjct: 295 VAAVIDCIGSCKGNTRLPGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPEDHIKA 354

Query: 288 KVLFALCSLLRHFPYAQRQFLKLGGLQVLRTL-VQEKGTEVLAVR 331
              +AL  + RH P   R       L VL +L +  + +E L V+
Sbjct: 355 AAAWALGQIGRHTPEHARAVAVTNTLPVLLSLYMSTESSEDLQVK 399


>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
          Length = 2017

 Score = 37.0 bits (84), Expect = 0.038
 Identities = 89/448 (19%), Positives = 171/448 (38%), Gaps = 48/448 (10%)

Query: 31   SHQNLKEF----ALTNPEKSSTKETERKETKAEEELDAEVLEVFHPTHEWQALQPGQAVP 86
            SH+ L++     ++   E    +E   + T   + L AE  EV     + +A   G+   
Sbjct: 664  SHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEA---GRVEL 720

Query: 87   AGSHVRLNLQTGEREAKLQYEDKFRNNLKGKRLDINTNTYTSQDLKSALAKFKEGAEMES 146
              S  +L  +    +  L        +L   +LD+N      ++ KSAL   +  AE E+
Sbjct: 721  ELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEA 780

Query: 147  SKEDKARQAEVKRLFRPIEELKKDFDELNVVIETDMQIMVRLINKFNSSSSSLEEKIAAL 206
            +   +  Q  ++ L    E  ++  +    V E   + + + +       S L+E++A L
Sbjct: 781  TVA-REEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQL 839

Query: 207  F-DLEYYVHQMDNAQDLLSFGGLQVVINGLNSTEPLVKEYAAFVL--------GAAFSSN 257
               L     +++ A+       ++ +       E L KE+A   +        G   S  
Sbjct: 840  SRQLSGREQELEQARREAQ-RQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEE 898

Query: 258  P---KVQVEAIEGGALQ---KLLVILATEQPLTAKKKVLFALCSLLRHFPYAQRQFLKLG 311
                +++ EA+EG   +   +L  + A  + L A+ + L      L           +L 
Sbjct: 899  ATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTG---------ELA 949

Query: 312  GLQVLRTLVQEKGTEVLAVRVVTLLYDLVTEKMFAEEEAELTQEMSPEKLQQYRQVHLLP 371
            GL+      QEK          +L  +L+ +K+  + E E    +  ++      +  L 
Sbjct: 950  GLRQQIIATQEK---------ASLDKELMAQKL-VQAEREAQASLREQRAAHEEDLQRLQ 999

Query: 372  GLWEQGWCEITAHLLALPEHDAREKVLQTLGVLLTTCRDRYRQD---PQLGRTLASLQAE 428
               E  W E+ A    L     RE+  + L   L   ++   ++    Q  R    L AE
Sbjct: 1000 REKEAAWRELEAERAQLQSQLQREQ--EELLARLEAEKEELSEEIAALQQERDEGLLLAE 1057

Query: 429  YQVLASLELQDGEDEGYFQELLGSVNSL 456
             +   +L L++ E     ++L+G+ +SL
Sbjct: 1058 SEKQQALSLKESEKTALSEKLMGTRHSL 1085


>gi|4758648 kinesin family member 5B [Homo sapiens]
          Length = 963

 Score = 36.6 bits (83), Expect = 0.049
 Identities = 55/298 (18%), Positives = 125/298 (41%), Gaps = 33/298 (11%)

Query: 92  RLNLQTGEREAKLQYEDKFRNNLKGKRLDINTNTYTSQDLKSALAKFKEGAEMESSK--- 148
           +L  Q  +++ ++  + +    LK + LD        ++L ++  + ++  + E ++   
Sbjct: 427 KLYKQLDDKDEEINQQSQLVEKLKTQMLD-------QEELLASTRRDQDNMQAELNRLQA 479

Query: 149 EDKARQAEVKRLFRPIEELKKDFDELNVVIETDMQIMVRLINKFNSSSSSLEEKIAALFD 208
           E+ A + EVK + + +EEL  ++D+ +  +E   +    L ++ N  S++L    A L  
Sbjct: 480 ENDASKEEVKEVLQALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSATLASIDAELQK 539

Query: 209 L-EYYVHQMDNAQDL-------LSFGGLQVVINGLNSTEPLVKEYAAFVLGAAFSSNPKV 260
           L E   HQ   A ++       L+  G+ V  N +   E        F +   + S  K 
Sbjct: 540 LKEMTNHQKKRAAEMMASLLKDLAEIGIAVGNNDVKQPEGTGMIDEEFTVARLYISKMKS 599

Query: 261 QVEAIEGGALQKLLVILATEQPLTAKKKVLFALCSLLRHFPYAQRQFLKLGGLQVLRTLV 320
           +V+ +     Q       + + +   +K L A C L      +Q +       + L+ + 
Sbjct: 600 EVKTMVKRCKQLESTQTESNKKMEENEKEL-AACQL----RISQHEAKIKSLTEYLQNVE 654

Query: 321 QEK----------GTEVLAVRVVTLLYDLVTEKMFAEEEAELTQEMSPEKLQQYRQVH 368
           Q+K            E++ +R    ++++  E +   + A   ++   +++Q +R+ H
Sbjct: 655 QKKRQLEESVDALSEELVQLRAQEKVHEMEKEHLNKVQTANEVKQAVEQQIQSHRETH 712


>gi|170650672 Leber congenital amaurosis 5 [Homo sapiens]
          Length = 697

 Score = 36.6 bits (83), Expect = 0.049
 Identities = 30/130 (23%), Positives = 63/130 (48%), Gaps = 11/130 (8%)

Query: 48  TKETERKETKAEEELDAEVLEVFHPTHEWQALQPGQAVPAGSHVRLNLQTGEREAKLQYE 107
           ++E ER   K  ++ ++E+        + + +   + +P    +   L + E    L+ +
Sbjct: 178 SQEKERATEKRVKDTESELFRTKFSLQKLKEISEARHLPERDDLAKKLVSAE----LKLD 233

Query: 108 DKFRNNLK-GKRLDINTNTYTSQDLKSALAKFKEGAEMESSKEDKARQAEVKRLFRPIEE 166
           D  R   +  K L+++TN++  Q     LA+ K     E+  E+K  Q EV+RL+  ++E
Sbjct: 234 DTERRIKELSKNLELSTNSFQRQ----LLAERKRA--YEAHDENKVLQKEVQRLYHKLKE 287

Query: 167 LKKDFDELNV 176
            +++ D  N+
Sbjct: 288 KERELDIKNI 297


>gi|170650670 Leber congenital amaurosis 5 [Homo sapiens]
          Length = 697

 Score = 36.6 bits (83), Expect = 0.049
 Identities = 30/130 (23%), Positives = 63/130 (48%), Gaps = 11/130 (8%)

Query: 48  TKETERKETKAEEELDAEVLEVFHPTHEWQALQPGQAVPAGSHVRLNLQTGEREAKLQYE 107
           ++E ER   K  ++ ++E+        + + +   + +P    +   L + E    L+ +
Sbjct: 178 SQEKERATEKRVKDTESELFRTKFSLQKLKEISEARHLPERDDLAKKLVSAE----LKLD 233

Query: 108 DKFRNNLK-GKRLDINTNTYTSQDLKSALAKFKEGAEMESSKEDKARQAEVKRLFRPIEE 166
           D  R   +  K L+++TN++  Q     LA+ K     E+  E+K  Q EV+RL+  ++E
Sbjct: 234 DTERRIKELSKNLELSTNSFQRQ----LLAERKRA--YEAHDENKVLQKEVQRLYHKLKE 287

Query: 167 LKKDFDELNV 176
            +++ D  N+
Sbjct: 288 KERELDIKNI 297


>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
            sapiens]
          Length = 1940

 Score = 36.2 bits (82), Expect = 0.064
 Identities = 99/447 (22%), Positives = 166/447 (37%), Gaps = 67/447 (14%)

Query: 31   SHQNLKEFALTNPEKSSTKETERKETKAEEELDAEVLEVFHPTHEWQALQPGQAVPAGSH 90
            S +  KE A    E   TK+   K     +EL+ +++ +    ++ Q       V A S 
Sbjct: 843  SAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQL-----QVQAESE 897

Query: 91   VRLNLQTGEREAKLQYEDKFRNNLKGKRLDINTNTYTSQDLKSALAKFKEGAEMESSKED 150
               NL   E       + KF+  L+ K  ++       +++ + L   K   E E S   
Sbjct: 898  ---NLLDAEERCDQLIKAKFQ--LEAKIKEVTERAEDEEEINAELTAKKRKLEDECS--- 949

Query: 151  KARQAEVKRLFRPIEELKKDFDELNVV---IETDMQIMVRLINKFNSSSSSLEEKIAALF 207
                           ELKKD D+L +    +E +       +       S L+E IA L 
Sbjct: 950  ---------------ELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKL- 993

Query: 208  DLEYYVHQMDNAQDLLSFGGLQVVINGLNSTEPLVKEYAAFVLGAAFSSNPKVQVE---- 263
              E    Q  + Q L      +  +N LN T+  +++     L ++     K++V+    
Sbjct: 994  TREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVE-DLESSLEQEKKLRVDLERN 1052

Query: 264  --AIEGG---ALQKLLVILATEQPLTAK-KKVLFALCSLLRHFPYAQR---QFLKLGGLQ 314
               +EG    A + +L +   +Q L  + KK  F  C L       Q    QF K   ++
Sbjct: 1053 KRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQK--KIK 1110

Query: 315  VLRTLVQEKGTEVLAVRVVTLLYDLVTEKM---FAEEEAELTQEMSPEKLQQYRQVHLLP 371
             L+  ++E   E+ A R         TEK    +A E  EL++ +         Q+ L  
Sbjct: 1111 ELQARIEELEEEIEAERATR----AKTEKQRSDYARELEELSERLEEAGGVTSTQIELNK 1166

Query: 372  GLWEQGWCEITAHLLALPEHDAREKVLQTLGVLLTTCRDRYRQDPQLGRTLASLQAEYQV 431
                    +  A  L L   D  E  LQ   ++    +       +LG  + +LQ   +V
Sbjct: 1167 --------KREAEFLKL-RRDLEEATLQHEAMVAALRKKHADSVAELGEQIDNLQ---RV 1214

Query: 432  LASLELQDGEDEGYFQELLGSVNSLLK 458
               LE +  E +    +L  S+ S+ K
Sbjct: 1215 KQKLEKEKSEFKLEIDDLSSSMESVSK 1241


>gi|7705415 hook homolog 1 [Homo sapiens]
          Length = 728

 Score = 35.8 bits (81), Expect = 0.084
 Identities = 45/195 (23%), Positives = 91/195 (46%), Gaps = 12/195 (6%)

Query: 36  KEFALTNPEKSSTKETERKETKAEEELDAEVL-----EVF-HPTHEWQALQPGQAVPAGS 89
           +E   +  ++    +T+   TK+ E L AE++     EVF    HE + L+  Q      
Sbjct: 428 EELRCSQVQQDHLNQTDASATKSYENLAAEIMPVEYREVFIRLQHENKMLRLQQEGSENE 487

Query: 90  HVRLNLQTGEREAKLQYEDKFRNNLKGKRLDINTNTYTSQDLKSALAKFKEGAEMESSKE 149
            +    +  E++ +   E +    L  +R  I       +DL+ +L +    +E ESS +
Sbjct: 488 RIEELQEQLEQKHRKMNELETEQRLSKER--IRELQQQIEDLQKSLQEQGSKSEGESSSK 545

Query: 150 DKAR-QAEVKRLFRPIEELKKDFDELNVVIETDMQIMVRLINKFNSSSSSLEEKIAALFD 208
            K + +A +++L    EEL+K   EL   ++ D+   V+ IN+  ++    +E + A+  
Sbjct: 546 LKQKLEAHMEKLTEVHEELQKK-QELIEDLQPDINQNVQKINELEAALQKKDEDMKAM-- 602

Query: 209 LEYYVHQMDNAQDLL 223
            E Y   ++ A++++
Sbjct: 603 EERYKMYLEKARNVI 617


>gi|29540566 armadillo repeat containing, X-linked 3 [Homo sapiens]
          Length = 379

 Score = 35.4 bits (80), Expect = 0.11
 Identities = 31/110 (28%), Positives = 52/110 (47%), Gaps = 5/110 (4%)

Query: 141 GAEMESSKEDKARQAEVKRLFRPIEELKKDFDELNVVIETDMQIMVRLINKFNSSSSSLE 200
           G E  +    +AR A   R  R +++      +  V+   ++Q ++ L+ + +     LE
Sbjct: 83  GTEAGTRARARAR-ARATRARRAVQKRASPNSDDTVLSPQELQKVLCLV-EMSEKPYILE 140

Query: 201 EKIAALFDLEYYVHQMDNAQDLLSFGGLQVVINGLNSTEPLVKEYAAFVL 250
             + AL +   Y    D  +DL   GGL +V   LN+ +P+VKE A  VL
Sbjct: 141 AALIALGNNAAYAFNRDIIRDL---GGLPIVAKILNTRDPIVKEKALIVL 187


>gi|29540564 armadillo repeat containing, X-linked 3 [Homo sapiens]
          Length = 379

 Score = 35.4 bits (80), Expect = 0.11
 Identities = 31/110 (28%), Positives = 52/110 (47%), Gaps = 5/110 (4%)

Query: 141 GAEMESSKEDKARQAEVKRLFRPIEELKKDFDELNVVIETDMQIMVRLINKFNSSSSSLE 200
           G E  +    +AR A   R  R +++      +  V+   ++Q ++ L+ + +     LE
Sbjct: 83  GTEAGTRARARAR-ARATRARRAVQKRASPNSDDTVLSPQELQKVLCLV-EMSEKPYILE 140

Query: 201 EKIAALFDLEYYVHQMDNAQDLLSFGGLQVVINGLNSTEPLVKEYAAFVL 250
             + AL +   Y    D  +DL   GGL +V   LN+ +P+VKE A  VL
Sbjct: 141 AALIALGNNAAYAFNRDIIRDL---GGLPIVAKILNTRDPIVKEKALIVL 187


>gi|7705274 armadillo repeat containing, X-linked 3 [Homo sapiens]
          Length = 379

 Score = 35.4 bits (80), Expect = 0.11
 Identities = 31/110 (28%), Positives = 52/110 (47%), Gaps = 5/110 (4%)

Query: 141 GAEMESSKEDKARQAEVKRLFRPIEELKKDFDELNVVIETDMQIMVRLINKFNSSSSSLE 200
           G E  +    +AR A   R  R +++      +  V+   ++Q ++ L+ + +     LE
Sbjct: 83  GTEAGTRARARAR-ARATRARRAVQKRASPNSDDTVLSPQELQKVLCLV-EMSEKPYILE 140

Query: 201 EKIAALFDLEYYVHQMDNAQDLLSFGGLQVVINGLNSTEPLVKEYAAFVL 250
             + AL +   Y    D  +DL   GGL +V   LN+ +P+VKE A  VL
Sbjct: 141 AALIALGNNAAYAFNRDIIRDL---GGLPIVAKILNTRDPIVKEKALIVL 187


>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
            sapiens]
          Length = 1938

 Score = 34.7 bits (78), Expect = 0.19
 Identities = 43/189 (22%), Positives = 73/189 (38%), Gaps = 25/189 (13%)

Query: 37   EFALTNPEKSSTKETERKETKAEEELDAEVLEVFHPTHEWQALQPGQAVPAGS------- 89
            E  LT  EK     TE K     EE+ A    +   T E ++LQ                
Sbjct: 962  ELTLTKVEKEK-HATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDK 1020

Query: 90   -------HVRLNLQTGEREAKLQYEDKFRNNLKGKRLDINTNTYTSQDLKSALAKFKEGA 142
                   + +L  QT + E  L+ E K R +L+  +  +  +   SQ+    L   K+  
Sbjct: 1021 VNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQI 1080

Query: 143  EME-SSKEDKARQAEVK---------RLFRPIEELKKDFDELNVVIETDMQIMVRLINKF 192
            E +   KE +  Q + K         +  + I+EL+   +EL   IE +  +  ++  + 
Sbjct: 1081 EEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQR 1140

Query: 193  NSSSSSLEE 201
            +  +  LEE
Sbjct: 1141 SDLARELEE 1149


>gi|118600973 RNA binding motif protein, X-linked 2 [Homo sapiens]
          Length = 322

 Score = 34.7 bits (78), Expect = 0.19
 Identities = 29/120 (24%), Positives = 57/120 (47%), Gaps = 12/120 (10%)

Query: 43  PEKSSTKETERKETKAEEELDAEVLEVFHPTHEWQALQPGQAVPAGSHVRLNLQTGEREA 102
           P K   K+ + K+ K +E+  A+         E QA QP  + P    V+    TG ++ 
Sbjct: 154 PTKKHKKDKKEKKKKKKEKEKAD--------REVQAEQPSSSSPRRKTVKEKDDTGPKKH 205

Query: 103 KLQYEDKFRNN--LKGKRLDINTNTYT--SQDLKSALAKFKEGAEMESSKEDKARQAEVK 158
             +  ++ + +   +G++L  +   Y+  ++DL+  L K K   E +SS   +AR+ + +
Sbjct: 206 SSKNSERAQKSEPREGQKLPKSRTAYSGGAEDLERELKKEKPKHEHKSSSRREAREEKTR 265


>gi|68299795 chromodomain helicase DNA binding protein 1 [Homo
           sapiens]
          Length = 1710

 Score = 34.7 bits (78), Expect = 0.19
 Identities = 31/147 (21%), Positives = 60/147 (40%), Gaps = 12/147 (8%)

Query: 46  SSTKETERKETKAEEELDAEVLEVFHPTHEWQALQPGQAVPAGSHVRLNLQTGER---EA 102
           +S  E +   ++  ++  +EV    H   +WQ    G    +GS      +  +    E 
Sbjct: 119 NSGSEEDSSSSEDSDDSSSEVKRKKHKDEDWQMSGSGSPSQSGSDSESEEEREKSSCDET 178

Query: 103 KLQYEDKFRNNLKGKRLDINTNTYTSQDLKSALAKFKEGAEMESSKED-------KARQA 155
           +  YE K  N +K ++    + +   + +     +  + +E +  +ED         RQA
Sbjct: 179 ESDYEPK--NKVKSRKPQNRSKSKNGKKILGQKKRQIDSSEEDDDEEDYDNDKRSSRRQA 236

Query: 156 EVKRLFRPIEELKKDFDELNVVIETDM 182
            V   ++  EE+K D D+L  V   D+
Sbjct: 237 TVNVSYKEDEEMKTDSDDLLEVCGEDV 263


>gi|29294627 PTPRF interacting protein binding protein 1 isoform 1
           [Homo sapiens]
          Length = 1005

 Score = 34.3 bits (77), Expect = 0.24
 Identities = 46/196 (23%), Positives = 86/196 (43%), Gaps = 39/196 (19%)

Query: 49  KETERKETKAEEELDAEVLEVFHPTHEWQALQPGQAVPAGSHVRLNLQTGEREAKLQYED 108
           +E   K    EE L  E+L     + E Q L     +   S+++L L   E++ +L YED
Sbjct: 142 EEHREKVNATEEMLQQELLS--RTSLETQKLDLMAEI---SNLKLKLTAVEKD-RLDYED 195

Query: 109 KFRNNLKGKRLDINTNTYTSQDLKSALAKFKEGAEMESSKEDKA--------RQAEVKRL 160
           KFR+  +G   +IN       ++ S   ++++  +++S+K++ A        +++EVKRL
Sbjct: 196 KFRDT-EGLIQEINDLRLKVSEMDSERLQYEK--KLKSTKDELASLKEQLEEKESEVKRL 252

Query: 161 FRPI---------------EELKKDFDELNVVIETDMQIMVRLINKFNSSSSSLEEKIAA 205
              +               E  KK   E N+ ++       ++     S  ++ EEK   
Sbjct: 253 QEKLVCKMKGEGVEIVDRDENFKKKLKEKNIEVQ-------KMKKAVESLMAANEEKDRK 305

Query: 206 LFDLEYYVHQMDNAQD 221
           + DL   +++    QD
Sbjct: 306 IEDLRQCLNRYKKMQD 321


>gi|4758650 kinesin family member 5C [Homo sapiens]
          Length = 957

 Score = 33.9 bits (76), Expect = 0.32
 Identities = 43/215 (20%), Positives = 95/215 (44%), Gaps = 22/215 (10%)

Query: 96  QTGEREAKLQYEDKFRNNLKGKRLDINTNTYTSQDLKSALAKFKEGAEMESSK---EDKA 152
           Q  +++ ++  + +    LK + LD         +L ++  +  E  + E ++   E++A
Sbjct: 427 QLDDKDDEINQQSQLAEKLKQQMLD-------QDELLASTRRDYEKIQEELTRLQIENEA 479

Query: 153 RQAEVKRLFRPIEELKKDFDELNVVIETDMQIMVRLINKFNSSSSSLEEKIAALFDL-EY 211
            + EVK + + +EEL  ++D+ +  +E   +   +L ++    +++L      L  L E 
Sbjct: 480 AKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQLQEL 539

Query: 212 YVHQMDNAQDLLS-----FGGLQVVINGLNSTEPLVKEYAA----FVLGAAFSSNPKVQV 262
             HQ   A ++L+      G +  +I G N  + L          F +   + S  K +V
Sbjct: 540 SNHQKKRATEILNLLLKDLGEIGGII-GTNDVKTLADVNGVIEEEFTMARLYISKMKSEV 598

Query: 263 EAIEGGALQKLLVILATEQPLTAKKKVLFALCSLL 297
           +++   + Q     + + + + A ++ L A C LL
Sbjct: 599 KSLVNRSKQLESAQMDSNRKMNASEREL-AACQLL 632



 Score = 33.9 bits (76), Expect = 0.32
 Identities = 42/171 (24%), Positives = 74/171 (43%), Gaps = 18/171 (10%)

Query: 45  KSSTKETERKETKAEEELDAEVLEVFHPTHEWQALQPGQAVPAGSHVRLNLQTG-----E 99
           +S+  ++ RK   +E EL A   ++    HE +       +      R  L+       E
Sbjct: 609 ESAQMDSNRKMNASERELAA--CQLLISQHEAKIKSLTDYMQNMEQKRRQLEESQDSLSE 666

Query: 100 REAKLQYEDKFRN-NLKGKRLDINTNTYTSQDLKSALAKFKEGAEMESSKEDKARQAEVK 158
             AKL+ ++K    + + K  +  T    ++++K AL +     +MES +E  A Q ++ 
Sbjct: 667 ELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQ-----QMESHRE--AHQKQLS 719

Query: 159 RLFRPIEELKKDFDE---LNVVIETDMQIMVRLINKFNSSSSSLEEKIAAL 206
           RL   IEE +K  DE   LN  ++ + + +    NK        E K+  L
Sbjct: 720 RLRDEIEEKQKIIDEIRDLNQKLQLEQEKLSSDYNKLKIEDQEREMKLEKL 770


>gi|41281683 disabled homolog 2 interacting protein isoform 2 [Homo
            sapiens]
          Length = 1065

 Score = 33.9 bits (76), Expect = 0.32
 Identities = 30/103 (29%), Positives = 49/103 (47%), Gaps = 4/103 (3%)

Query: 136  AKFKEGAE-MESSKEDKARQAE--VKRLFRPIEELKKDFDELNVVIETDMQIMVRLINKF 192
            A+ +EG E +   +EDK  Q +  + RL    EELKKD  E+   +++  +I+     + 
Sbjct: 955  ARLEEGEERLRRQQEDKDIQMKGIISRLMSVEEELKKDHAEMQAAVDSKQKIIDAQEKRI 1014

Query: 193  NSSSSSLEEKIAALFDL-EYYVHQMDNAQDLLSFGGLQVVING 234
             S  ++    ++AL  L E Y  Q  N     +   LQ+  NG
Sbjct: 1015 ASLDAANARLMSALTQLKERYSMQARNGISPTNPTKLQITENG 1057


>gi|211059433 coiled-coil domain containing 79 [Homo sapiens]
          Length = 727

 Score = 33.9 bits (76), Expect = 0.32
 Identities = 34/144 (23%), Positives = 60/144 (41%), Gaps = 5/144 (3%)

Query: 178 IETDMQIMVRLINKFNSSSSSLEEKIAALFDLEYYVHQMDNAQDLL-SFGGLQVVINGLN 236
           ++TD+ +++  +     ++ S +E   AL  +     Q  NA       GGL  V N   
Sbjct: 12  MKTDLNLLLECLKYQMDNAFSQKE---ALVTIHSICQQNSNASVYFREIGGLMFVKNLAK 68

Query: 237 STE-PLVKEYAAFVLGAAFSSNPKVQVEAIEGGALQKLLVILATEQPLTAKKKVLFALCS 295
           S+E  +VKE A + LGA    N   Q         + L   L+ +  +  K+  ++ +  
Sbjct: 69  SSEHSMVKEAALYTLGAIAEKNVYCQQTLCTSELFEDLTWFLSNDSNINLKRMSVYVILV 128

Query: 296 LLRHFPYAQRQFLKLGGLQVLRTL 319
           L+ +    Q    + G + VL  L
Sbjct: 129 LVSNNRTGQTLVRETGCITVLSRL 152


>gi|148839339 nexilin (F actin binding protein) [Homo sapiens]
          Length = 675

 Score = 33.9 bits (76), Expect = 0.32
 Identities = 42/171 (24%), Positives = 77/171 (45%), Gaps = 24/171 (14%)

Query: 44  EKSSTKETERKETKAEEELDAEVLEVFHPTHEWQALQPGQAVPAGSHVRLNLQTG----- 98
           ++ S KE +      ++E+++E  +        ++L PG+       +    Q       
Sbjct: 215 QRPSLKEAKCLSLVMDDEIESEAKK--------ESLSPGKLKLTFEELERQRQENRKKQA 266

Query: 99  EREAKLQYEDKFRNNLKGKRLDINTNTYTSQDLKSALAKFKEGA------EMESSK-EDK 151
           E EA+ + E++ R   + +R  +N +   +QD       ++ G       EME  + ED+
Sbjct: 267 EEEARKRLEEEKRAFEEARRQMVNEDE-ENQDTAKIFKGYRPGKLKLSFEEMERQRREDE 325

Query: 152 ARQAEVKRLFRPIEELKKDFDEL--NVVIETDMQIMVRLINKFNSSSSSLE 200
            R+AE +   R IEE KK F E   N+V++ D   M + I++   +   LE
Sbjct: 326 KRKAE-EEARRRIEEEKKAFAEARRNMVVDDDSPEMYKTISQEFLTPGKLE 375


>gi|37588869 ring finger protein 123 [Homo sapiens]
          Length = 1314

 Score = 33.5 bits (75), Expect = 0.42
 Identities = 36/141 (25%), Positives = 63/141 (44%), Gaps = 9/141 (6%)

Query: 260 VQVEAIEGGALQKLLVILATEQPLTAKKKVLFALCSLLRHF-PYAQRQFLKLGGLQVLRT 318
           V+++ +EG  L K     +++  L  +  VL  L  +  HF P  ++ +L    L     
Sbjct: 288 VELDPVEGRLLDKE----SSKWRLRGQPTVLLTLAHIFHHFAPLLRKVYLVEAVLMSFLL 343

Query: 319 LVQEKGTEVLAVRVVTLLYDLVTEKMFAEEEAELTQEMSPEKLQQYRQVHLLPGLWEQ-G 377
            + EKGT   A  VV  + DL+   M   E  +  +++    L+ YR   ++P L  Q  
Sbjct: 344 GIVEKGTPTQAQSVVHQVLDLLWLFMEDYEVQDCLKQLMMSLLRLYRFSPIVPDLGLQIH 403

Query: 378 WCEITAHLLALPEHDAREKVL 398
           +  +T   +A+  H+   K L
Sbjct: 404 YLRLT---IAILRHEKSRKFL 421


>gi|150170718 zinc finger protein 292 [Homo sapiens]
          Length = 2723

 Score = 33.5 bits (75), Expect = 0.42
 Identities = 32/176 (18%), Positives = 71/176 (40%), Gaps = 10/176 (5%)

Query: 39   ALTNPEKSSTKETERKETKAEEELDAEVLEVFHPTHEWQALQPGQAVPAGSHVRLNLQTG 98
            ALTN +    K    K+ K E++    V +       +   +P + V  G      +Q  
Sbjct: 2071 ALTNTQTKGRKIRRHKKEKEEKKRKKPVSQSLEFPTRYSPYRPYRCVHQGCFAAFTIQ-- 2128

Query: 99   EREAKLQYEDKFRNNLKGKRLDINTNTYTSQDLKSALAKFKEGAEMESSKEDKARQAEVK 158
             +   L Y+   +++L     ++   +   ++ +    K       ++ KE + + ++  
Sbjct: 2129 -QNLILHYQAVHKSDLPAFSAEVEEESEAGKESEETETK-------QTLKEFRCQVSDCS 2180

Query: 159  RLFRPIEELKKDFDELNVVIETDMQIMVRLINKFNSSSSSLEEKIAALFDLEYYVH 214
            R+F+ I  L + + +L+ +   +++ M   ++        LE K +    L Y VH
Sbjct: 2181 RIFQAITGLIQHYMKLHEMTPEEIESMTASVDVGKFPCDQLECKSSFTTYLNYVVH 2236


>gi|7662162 ALEX2 protein [Homo sapiens]
          Length = 632

 Score = 33.5 bits (75), Expect = 0.42
 Identities = 26/110 (23%), Positives = 52/110 (47%), Gaps = 6/110 (5%)

Query: 143 EMESSKEDKARQAEVKRLFRPIEELKKDFD-ELNVVIET-DMQIMVRLINKFNSSSSSLE 200
           + ES  + +       R  RP+   K+ F  E++ ++   D++ ++ L+ K  S    ++
Sbjct: 347 DTESDSDSEPETQRRGRGRRPVAMQKRPFPYEIDEILGVRDLRKVLALLQK--SDDPFIQ 404

Query: 201 EKIAALFDLEYYVHQMDNAQDLLSFGGLQVVINGLNSTEPLVKEYAAFVL 250
           +   AL  L    +   N + +   GGL ++ N +N T+P +KE A   +
Sbjct: 405 Q--VALLTLSNNANYSCNQETIRKLGGLPIIANMINKTDPHIKEKALMAM 452


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.132    0.365 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,791,319
Number of Sequences: 37866
Number of extensions: 658114
Number of successful extensions: 3123
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 92
Number of HSP's that attempted gapping in prelim test: 3014
Number of HSP's gapped (non-prelim): 210
length of query: 461
length of database: 18,247,518
effective HSP length: 106
effective length of query: 355
effective length of database: 14,233,722
effective search space: 5052971310
effective search space used: 5052971310
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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