BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|11968009 SIL1 protein precursor [Homo sapiens] (461 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|11968009 SIL1 protein precursor [Homo sapiens] 898 0.0 gi|83641896 SIL1 protein precursor [Homo sapiens] 898 0.0 gi|194294548 hsp70-interacting protein [Homo sapiens] 54 3e-07 gi|112363070 hsp70-interacting protein [Homo sapiens] 54 3e-07 gi|19924131 RAD50 homolog isoform 2 [Homo sapiens] 42 0.002 gi|19924129 RAD50 homolog isoform 1 [Homo sapiens] 42 0.002 gi|226958575 RAS protein activator like 2 isoform 2 [Homo sapiens] 40 0.003 gi|4758808 RAS protein activator like 2 isoform 1 [Homo sapiens] 40 0.003 gi|6912678 sperm associated antigen 6 isoform 1 [Homo sapiens] 40 0.004 gi|27262641 sperm associated antigen 6 isoform 2 [Homo sapiens] 40 0.004 gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 37 0.038 gi|4758648 kinesin family member 5B [Homo sapiens] 37 0.049 gi|170650672 Leber congenital amaurosis 5 [Homo sapiens] 37 0.049 gi|170650670 Leber congenital amaurosis 5 [Homo sapiens] 37 0.049 gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 36 0.064 gi|7705415 hook homolog 1 [Homo sapiens] 36 0.084 gi|29540566 armadillo repeat containing, X-linked 3 [Homo sapiens] 35 0.11 gi|29540564 armadillo repeat containing, X-linked 3 [Homo sapiens] 35 0.11 gi|7705274 armadillo repeat containing, X-linked 3 [Homo sapiens] 35 0.11 gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 35 0.19 gi|118600973 RNA binding motif protein, X-linked 2 [Homo sapiens] 35 0.19 gi|68299795 chromodomain helicase DNA binding protein 1 [Homo sa... 35 0.19 gi|29294627 PTPRF interacting protein binding protein 1 isoform ... 34 0.24 gi|4758650 kinesin family member 5C [Homo sapiens] 34 0.32 gi|41281683 disabled homolog 2 interacting protein isoform 2 [Ho... 34 0.32 gi|211059433 coiled-coil domain containing 79 [Homo sapiens] 34 0.32 gi|148839339 nexilin (F actin binding protein) [Homo sapiens] 34 0.32 gi|37588869 ring finger protein 123 [Homo sapiens] 33 0.42 gi|150170718 zinc finger protein 292 [Homo sapiens] 33 0.42 gi|7662162 ALEX2 protein [Homo sapiens] 33 0.42 >gi|11968009 SIL1 protein precursor [Homo sapiens] Length = 461 Score = 898 bits (2321), Expect = 0.0 Identities = 461/461 (100%), Positives = 461/461 (100%) Query: 1 MAPQSLPSSRMAPLGMLLGLLMAACFTFCLSHQNLKEFALTNPEKSSTKETERKETKAEE 60 MAPQSLPSSRMAPLGMLLGLLMAACFTFCLSHQNLKEFALTNPEKSSTKETERKETKAEE Sbjct: 1 MAPQSLPSSRMAPLGMLLGLLMAACFTFCLSHQNLKEFALTNPEKSSTKETERKETKAEE 60 Query: 61 ELDAEVLEVFHPTHEWQALQPGQAVPAGSHVRLNLQTGEREAKLQYEDKFRNNLKGKRLD 120 ELDAEVLEVFHPTHEWQALQPGQAVPAGSHVRLNLQTGEREAKLQYEDKFRNNLKGKRLD Sbjct: 61 ELDAEVLEVFHPTHEWQALQPGQAVPAGSHVRLNLQTGEREAKLQYEDKFRNNLKGKRLD 120 Query: 121 INTNTYTSQDLKSALAKFKEGAEMESSKEDKARQAEVKRLFRPIEELKKDFDELNVVIET 180 INTNTYTSQDLKSALAKFKEGAEMESSKEDKARQAEVKRLFRPIEELKKDFDELNVVIET Sbjct: 121 INTNTYTSQDLKSALAKFKEGAEMESSKEDKARQAEVKRLFRPIEELKKDFDELNVVIET 180 Query: 181 DMQIMVRLINKFNSSSSSLEEKIAALFDLEYYVHQMDNAQDLLSFGGLQVVINGLNSTEP 240 DMQIMVRLINKFNSSSSSLEEKIAALFDLEYYVHQMDNAQDLLSFGGLQVVINGLNSTEP Sbjct: 181 DMQIMVRLINKFNSSSSSLEEKIAALFDLEYYVHQMDNAQDLLSFGGLQVVINGLNSTEP 240 Query: 241 LVKEYAAFVLGAAFSSNPKVQVEAIEGGALQKLLVILATEQPLTAKKKVLFALCSLLRHF 300 LVKEYAAFVLGAAFSSNPKVQVEAIEGGALQKLLVILATEQPLTAKKKVLFALCSLLRHF Sbjct: 241 LVKEYAAFVLGAAFSSNPKVQVEAIEGGALQKLLVILATEQPLTAKKKVLFALCSLLRHF 300 Query: 301 PYAQRQFLKLGGLQVLRTLVQEKGTEVLAVRVVTLLYDLVTEKMFAEEEAELTQEMSPEK 360 PYAQRQFLKLGGLQVLRTLVQEKGTEVLAVRVVTLLYDLVTEKMFAEEEAELTQEMSPEK Sbjct: 301 PYAQRQFLKLGGLQVLRTLVQEKGTEVLAVRVVTLLYDLVTEKMFAEEEAELTQEMSPEK 360 Query: 361 LQQYRQVHLLPGLWEQGWCEITAHLLALPEHDAREKVLQTLGVLLTTCRDRYRQDPQLGR 420 LQQYRQVHLLPGLWEQGWCEITAHLLALPEHDAREKVLQTLGVLLTTCRDRYRQDPQLGR Sbjct: 361 LQQYRQVHLLPGLWEQGWCEITAHLLALPEHDAREKVLQTLGVLLTTCRDRYRQDPQLGR 420 Query: 421 TLASLQAEYQVLASLELQDGEDEGYFQELLGSVNSLLKELR 461 TLASLQAEYQVLASLELQDGEDEGYFQELLGSVNSLLKELR Sbjct: 421 TLASLQAEYQVLASLELQDGEDEGYFQELLGSVNSLLKELR 461 >gi|83641896 SIL1 protein precursor [Homo sapiens] Length = 461 Score = 898 bits (2321), Expect = 0.0 Identities = 461/461 (100%), Positives = 461/461 (100%) Query: 1 MAPQSLPSSRMAPLGMLLGLLMAACFTFCLSHQNLKEFALTNPEKSSTKETERKETKAEE 60 MAPQSLPSSRMAPLGMLLGLLMAACFTFCLSHQNLKEFALTNPEKSSTKETERKETKAEE Sbjct: 1 MAPQSLPSSRMAPLGMLLGLLMAACFTFCLSHQNLKEFALTNPEKSSTKETERKETKAEE 60 Query: 61 ELDAEVLEVFHPTHEWQALQPGQAVPAGSHVRLNLQTGEREAKLQYEDKFRNNLKGKRLD 120 ELDAEVLEVFHPTHEWQALQPGQAVPAGSHVRLNLQTGEREAKLQYEDKFRNNLKGKRLD Sbjct: 61 ELDAEVLEVFHPTHEWQALQPGQAVPAGSHVRLNLQTGEREAKLQYEDKFRNNLKGKRLD 120 Query: 121 INTNTYTSQDLKSALAKFKEGAEMESSKEDKARQAEVKRLFRPIEELKKDFDELNVVIET 180 INTNTYTSQDLKSALAKFKEGAEMESSKEDKARQAEVKRLFRPIEELKKDFDELNVVIET Sbjct: 121 INTNTYTSQDLKSALAKFKEGAEMESSKEDKARQAEVKRLFRPIEELKKDFDELNVVIET 180 Query: 181 DMQIMVRLINKFNSSSSSLEEKIAALFDLEYYVHQMDNAQDLLSFGGLQVVINGLNSTEP 240 DMQIMVRLINKFNSSSSSLEEKIAALFDLEYYVHQMDNAQDLLSFGGLQVVINGLNSTEP Sbjct: 181 DMQIMVRLINKFNSSSSSLEEKIAALFDLEYYVHQMDNAQDLLSFGGLQVVINGLNSTEP 240 Query: 241 LVKEYAAFVLGAAFSSNPKVQVEAIEGGALQKLLVILATEQPLTAKKKVLFALCSLLRHF 300 LVKEYAAFVLGAAFSSNPKVQVEAIEGGALQKLLVILATEQPLTAKKKVLFALCSLLRHF Sbjct: 241 LVKEYAAFVLGAAFSSNPKVQVEAIEGGALQKLLVILATEQPLTAKKKVLFALCSLLRHF 300 Query: 301 PYAQRQFLKLGGLQVLRTLVQEKGTEVLAVRVVTLLYDLVTEKMFAEEEAELTQEMSPEK 360 PYAQRQFLKLGGLQVLRTLVQEKGTEVLAVRVVTLLYDLVTEKMFAEEEAELTQEMSPEK Sbjct: 301 PYAQRQFLKLGGLQVLRTLVQEKGTEVLAVRVVTLLYDLVTEKMFAEEEAELTQEMSPEK 360 Query: 361 LQQYRQVHLLPGLWEQGWCEITAHLLALPEHDAREKVLQTLGVLLTTCRDRYRQDPQLGR 420 LQQYRQVHLLPGLWEQGWCEITAHLLALPEHDAREKVLQTLGVLLTTCRDRYRQDPQLGR Sbjct: 361 LQQYRQVHLLPGLWEQGWCEITAHLLALPEHDAREKVLQTLGVLLTTCRDRYRQDPQLGR 420 Query: 421 TLASLQAEYQVLASLELQDGEDEGYFQELLGSVNSLLKELR 461 TLASLQAEYQVLASLELQDGEDEGYFQELLGSVNSLLKELR Sbjct: 421 TLASLQAEYQVLASLELQDGEDEGYFQELLGSVNSLLKELR 461 >gi|194294548 hsp70-interacting protein [Homo sapiens] Length = 359 Score = 53.9 bits (128), Expect = 3e-07 Identities = 42/142 (29%), Positives = 71/142 (50%), Gaps = 2/142 (1%) Query: 200 EEKIAALFDLEYYVHQMDNAQDLLSFGGLQVVING-LNSTEPLVKEYAAFVLGAAFSSNP 258 +E+ AL L MDNA D G+ +++ L + ++ AA ++G + Sbjct: 118 QEREGALELLADLCENMDNAADFCQLSGMHLLVGRYLEAGAAGLRWRAAQLIGTCSQNVA 177 Query: 259 KVQVEAIEGGALQKLLVILATEQPLTAKKKVLFALCSLLRHFPYAQRQFLKLGGLQVLRT 318 +Q + + GAL+KLL +L + T + K LFA+ L+R QFL+L G VL Sbjct: 178 AIQEQVLGLGALRKLLRLLDRDACDTVRVKALFAISCLVREQEAGLLQFLRLDGFSVLMR 237 Query: 319 LVQEKGTEVLAVRVVTLLYDLV 340 +Q++ + L V+ LL +L+ Sbjct: 238 AMQQQ-VQKLKVKSAFLLQNLL 258 Score = 37.4 bits (85), Expect = 0.029 Identities = 27/106 (25%), Positives = 49/106 (46%), Gaps = 2/106 (1%) Query: 202 KIAALFDLEYYVHQMD-NAQDLLSFGGLQVVINGLNSTEPLVKEYAAFVLGAAFSSNPKV 260 ++ ALF + V + + L G V++ + +K +AF+L +P+ Sbjct: 205 RVKALFAISCLVREQEAGLLQFLRLDGFSVLMRAMQQQVQKLKVKSAFLLQNLLVGHPEH 264 Query: 261 QVEAIEGGALQKLLVILATEQPLTAKKKVLFALCSLLRHFPYAQRQ 306 + G +Q+L+ ++ TE + VL ALCSL+ FP R+ Sbjct: 265 KGTLCSMGMVQQLVALVRTEHS-PFHEHVLGALCSLVTDFPQGVRE 309 >gi|112363070 hsp70-interacting protein [Homo sapiens] Length = 359 Score = 53.9 bits (128), Expect = 3e-07 Identities = 42/142 (29%), Positives = 71/142 (50%), Gaps = 2/142 (1%) Query: 200 EEKIAALFDLEYYVHQMDNAQDLLSFGGLQVVING-LNSTEPLVKEYAAFVLGAAFSSNP 258 +E+ AL L MDNA D G+ +++ L + ++ AA ++G + Sbjct: 118 QEREGALELLADLCENMDNAADFCQLSGMHLLVGRYLEAGAAGLRWRAAQLIGTCSQNVA 177 Query: 259 KVQVEAIEGGALQKLLVILATEQPLTAKKKVLFALCSLLRHFPYAQRQFLKLGGLQVLRT 318 +Q + + GAL+KLL +L + T + K LFA+ L+R QFL+L G VL Sbjct: 178 AIQEQVLGLGALRKLLRLLDRDACDTVRVKALFAISCLVREQEAGLLQFLRLDGFSVLMR 237 Query: 319 LVQEKGTEVLAVRVVTLLYDLV 340 +Q++ + L V+ LL +L+ Sbjct: 238 AMQQQ-VQKLKVKSAFLLQNLL 258 Score = 37.4 bits (85), Expect = 0.029 Identities = 27/106 (25%), Positives = 49/106 (46%), Gaps = 2/106 (1%) Query: 202 KIAALFDLEYYVHQMD-NAQDLLSFGGLQVVINGLNSTEPLVKEYAAFVLGAAFSSNPKV 260 ++ ALF + V + + L G V++ + +K +AF+L +P+ Sbjct: 205 RVKALFAISCLVREQEAGLLQFLRLDGFSVLMRAMQQQVQKLKVKSAFLLQNLLVGHPEH 264 Query: 261 QVEAIEGGALQKLLVILATEQPLTAKKKVLFALCSLLRHFPYAQRQ 306 + G +Q+L+ ++ TE + VL ALCSL+ FP R+ Sbjct: 265 KGTLCSMGMVQQLVALVRTEHS-PFHEHVLGALCSLVTDFPQGVRE 309 >gi|19924131 RAD50 homolog isoform 2 [Homo sapiens] Length = 1173 Score = 41.6 bits (96), Expect = 0.002 Identities = 26/105 (24%), Positives = 48/105 (45%), Gaps = 15/105 (14%) Query: 99 EREAKLQYEDKFRNNLKGKRLDINTNTYTSQDLKSALAKFKEGAEMESSKEDKARQAEVK 158 +++ ++Q+ N LK ++L I+TN Q L+ + EV+ Sbjct: 716 DQQEQIQHLKSTTNELKSEKLQISTNLQRRQQLEEQTVELS---------------TEVQ 760 Query: 159 RLFRPIEELKKDFDELNVVIETDMQIMVRLINKFNSSSSSLEEKI 203 L+R I++ K+ L +E Q LINK N+S+ ++K+ Sbjct: 761 SLYREIKDAKEQVSPLETTLEKFQQEKEELINKKNTSNKIAQDKL 805 >gi|19924129 RAD50 homolog isoform 1 [Homo sapiens] Length = 1312 Score = 41.6 bits (96), Expect = 0.002 Identities = 26/105 (24%), Positives = 48/105 (45%), Gaps = 15/105 (14%) Query: 99 EREAKLQYEDKFRNNLKGKRLDINTNTYTSQDLKSALAKFKEGAEMESSKEDKARQAEVK 158 +++ ++Q+ N LK ++L I+TN Q L+ + EV+ Sbjct: 855 DQQEQIQHLKSTTNELKSEKLQISTNLQRRQQLEEQTVELS---------------TEVQ 899 Query: 159 RLFRPIEELKKDFDELNVVIETDMQIMVRLINKFNSSSSSLEEKI 203 L+R I++ K+ L +E Q LINK N+S+ ++K+ Sbjct: 900 SLYREIKDAKEQVSPLETTLEKFQQEKEELINKKNTSNKIAQDKL 944 >gi|226958575 RAS protein activator like 2 isoform 2 [Homo sapiens] Length = 1280 Score = 40.4 bits (93), Expect = 0.003 Identities = 60/255 (23%), Positives = 102/255 (40%), Gaps = 28/255 (10%) Query: 2 APQSLPSSRMAPLGMLLGLLMAACFTFCLSHQNLKEFALTNPEKSSTKET--------ER 53 AP SLP S + ++ AA L + ++ + + + SS++E+ +R Sbjct: 1025 APPSLPHSASLRSTGSMSVVSAA-----LVAEPVQNGSRSRQQSSSSRESPVPKVRAIQR 1079 Query: 54 KETK-AEEELDAEVLEVFHPTHEWQALQPGQAVPAGSHVRLNLQTGEREAKLQYED---K 109 ++T+ + +D+ + T W L GQ NL + K + E K Sbjct: 1080 QQTQQVQSPVDSATMSPVERTAAW-VLNNGQYEEDVEETEQNLDEAKHAEKYEQEITKLK 1138 Query: 110 FRNNLKGKRLDINTNTYTSQDLKSALAKFKEGAEMESSKEDKARQAEVK---------RL 160 R + +RL+ Q+ + + A +E S+E RQ E K RL Sbjct: 1139 ERLRVSSRRLEEYERRLLVQEQQMQKLLLEYKARLEDSEERLRRQQEEKDSQMKSIISRL 1198 Query: 161 FRPIEELKKDFDELNVVIETDMQIMVRLINKFNSSSSSLEEKIAALFDL-EYYVHQMDNA 219 EELKKD E+ VI+ +I+ + S S+ ++AL + E Y Q+ N Sbjct: 1199 MAVEEELKKDHAEMQAVIDAKQKIIDAQEKRIVSLDSANTRLMSALTQVKERYSMQVRNG 1258 Query: 220 QDLLSFGGLQVVING 234 + L + NG Sbjct: 1259 ISPTNPTKLSITENG 1273 >gi|4758808 RAS protein activator like 2 isoform 1 [Homo sapiens] Length = 1139 Score = 40.4 bits (93), Expect = 0.003 Identities = 60/255 (23%), Positives = 102/255 (40%), Gaps = 28/255 (10%) Query: 2 APQSLPSSRMAPLGMLLGLLMAACFTFCLSHQNLKEFALTNPEKSSTKET--------ER 53 AP SLP S + ++ AA L + ++ + + + SS++E+ +R Sbjct: 884 APPSLPHSASLRSTGSMSVVSAA-----LVAEPVQNGSRSRQQSSSSRESPVPKVRAIQR 938 Query: 54 KETK-AEEELDAEVLEVFHPTHEWQALQPGQAVPAGSHVRLNLQTGEREAKLQYED---K 109 ++T+ + +D+ + T W L GQ NL + K + E K Sbjct: 939 QQTQQVQSPVDSATMSPVERTAAW-VLNNGQYEEDVEETEQNLDEAKHAEKYEQEITKLK 997 Query: 110 FRNNLKGKRLDINTNTYTSQDLKSALAKFKEGAEMESSKEDKARQAEVK---------RL 160 R + +RL+ Q+ + + A +E S+E RQ E K RL Sbjct: 998 ERLRVSSRRLEEYERRLLVQEQQMQKLLLEYKARLEDSEERLRRQQEEKDSQMKSIISRL 1057 Query: 161 FRPIEELKKDFDELNVVIETDMQIMVRLINKFNSSSSSLEEKIAALFDL-EYYVHQMDNA 219 EELKKD E+ VI+ +I+ + S S+ ++AL + E Y Q+ N Sbjct: 1058 MAVEEELKKDHAEMQAVIDAKQKIIDAQEKRIVSLDSANTRLMSALTQVKERYSMQVRNG 1117 Query: 220 QDLLSFGGLQVVING 234 + L + NG Sbjct: 1118 ISPTNPTKLSITENG 1132 >gi|6912678 sperm associated antigen 6 isoform 1 [Homo sapiens] Length = 509 Score = 40.0 bits (92), Expect = 0.004 Identities = 27/107 (25%), Positives = 48/107 (44%), Gaps = 1/107 (0%) Query: 214 HQMDNAQDLLSFGGLQVVINGLNSTEPLVKEYAAFVLGAAFSSNPKVQVEAIEGGALQKL 273 H AQ ++ G L ++ L +P VKE AA+ L N ++ ++ GA+ L Sbjct: 113 HSPQLAQAIVDCGALDTLVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAV-PL 171 Query: 274 LVILATEQPLTAKKKVLFALCSLLRHFPYAQRQFLKLGGLQVLRTLV 320 LV+ E + K+ AL + +H P + + G + L ++ Sbjct: 172 LVLCIQEPEIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMI 218 Score = 34.7 bits (78), Expect = 0.19 Identities = 27/106 (25%), Positives = 48/106 (45%), Gaps = 1/106 (0%) Query: 217 DNAQDLLSFGGLQVVINGLNSTEPLVKEYAAFVLGAAFSSNPKVQVEAIEGGALQKLLVI 276 D A+ ++ L ++ L K+ AAFVL A +P++ ++ GAL L++ Sbjct: 74 DLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQAIVDCGALDTLVIC 133 Query: 277 LATEQPLTAKKKVLFALCSLLRHFPYAQRQFLKLGGLQVLRTLVQE 322 L P K+ +AL + RH + + G + +L +QE Sbjct: 134 LEDFDP-GVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQE 178 Score = 30.4 bits (67), Expect = 3.5 Identities = 37/165 (22%), Positives = 69/165 (41%), Gaps = 4/165 (2%) Query: 168 KKDFDELNVVIETDMQIMVRLINKFNSSSSSLEEKIAALFDLEYYVHQMDNAQDLLSFGG 227 K D +V+E ++ +V K +K A+ E H + +Q +++ GG Sbjct: 238 KHSVDLAEMVVEAEIFPVVLTCLK---DKDEYVKKNASTLIREIAKHTPELSQLVVNAGG 294 Query: 228 LQVVINGLNSTEPLVKEYAAFVLGAAFSSNPKVQVEAIEGGALQKLLVILATEQPLTAKK 287 + VI+ + S + + +LG + + + + I + +L V L+ E K Sbjct: 295 VAAVIDCIGSCKGNTRLPGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPEDHIKA 354 Query: 288 KVLFALCSLLRHFPYAQRQFLKLGGLQVLRTL-VQEKGTEVLAVR 331 +AL + RH P R L VL +L + + +E L V+ Sbjct: 355 AAAWALGQIGRHTPEHARAVAVTNTLPVLLSLYMSTESSEDLQVK 399 >gi|27262641 sperm associated antigen 6 isoform 2 [Homo sapiens] Length = 458 Score = 40.0 bits (92), Expect = 0.004 Identities = 27/107 (25%), Positives = 48/107 (44%), Gaps = 1/107 (0%) Query: 214 HQMDNAQDLLSFGGLQVVINGLNSTEPLVKEYAAFVLGAAFSSNPKVQVEAIEGGALQKL 273 H AQ ++ G L ++ L +P VKE AA+ L N ++ ++ GA+ L Sbjct: 113 HSPQLAQAIVDCGALDTLVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAV-PL 171 Query: 274 LVILATEQPLTAKKKVLFALCSLLRHFPYAQRQFLKLGGLQVLRTLV 320 LV+ E + K+ AL + +H P + + G + L ++ Sbjct: 172 LVLCIQEPEIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMI 218 Score = 34.7 bits (78), Expect = 0.19 Identities = 27/106 (25%), Positives = 48/106 (45%), Gaps = 1/106 (0%) Query: 217 DNAQDLLSFGGLQVVINGLNSTEPLVKEYAAFVLGAAFSSNPKVQVEAIEGGALQKLLVI 276 D A+ ++ L ++ L K+ AAFVL A +P++ ++ GAL L++ Sbjct: 74 DLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQAIVDCGALDTLVIC 133 Query: 277 LATEQPLTAKKKVLFALCSLLRHFPYAQRQFLKLGGLQVLRTLVQE 322 L P K+ +AL + RH + + G + +L +QE Sbjct: 134 LEDFDP-GVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQE 178 Score = 30.4 bits (67), Expect = 3.5 Identities = 37/165 (22%), Positives = 69/165 (41%), Gaps = 4/165 (2%) Query: 168 KKDFDELNVVIETDMQIMVRLINKFNSSSSSLEEKIAALFDLEYYVHQMDNAQDLLSFGG 227 K D +V+E ++ +V K +K A+ E H + +Q +++ GG Sbjct: 238 KHSVDLAEMVVEAEIFPVVLTCLK---DKDEYVKKNASTLIREIAKHTPELSQLVVNAGG 294 Query: 228 LQVVINGLNSTEPLVKEYAAFVLGAAFSSNPKVQVEAIEGGALQKLLVILATEQPLTAKK 287 + VI+ + S + + +LG + + + + I + +L V L+ E K Sbjct: 295 VAAVIDCIGSCKGNTRLPGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPEDHIKA 354 Query: 288 KVLFALCSLLRHFPYAQRQFLKLGGLQVLRTL-VQEKGTEVLAVR 331 +AL + RH P R L VL +L + + +E L V+ Sbjct: 355 AAAWALGQIGRHTPEHARAVAVTNTLPVLLSLYMSTESSEDLQVK 399 >gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] Length = 2017 Score = 37.0 bits (84), Expect = 0.038 Identities = 89/448 (19%), Positives = 171/448 (38%), Gaps = 48/448 (10%) Query: 31 SHQNLKEF----ALTNPEKSSTKETERKETKAEEELDAEVLEVFHPTHEWQALQPGQAVP 86 SH+ L++ ++ E +E + T + L AE EV + +A G+ Sbjct: 664 SHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEA---GRVEL 720 Query: 87 AGSHVRLNLQTGEREAKLQYEDKFRNNLKGKRLDINTNTYTSQDLKSALAKFKEGAEMES 146 S +L + + L +L +LD+N ++ KSAL + AE E+ Sbjct: 721 ELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEA 780 Query: 147 SKEDKARQAEVKRLFRPIEELKKDFDELNVVIETDMQIMVRLINKFNSSSSSLEEKIAAL 206 + + Q ++ L E ++ + V E + + + + S L+E++A L Sbjct: 781 TVA-REEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQL 839 Query: 207 F-DLEYYVHQMDNAQDLLSFGGLQVVINGLNSTEPLVKEYAAFVL--------GAAFSSN 257 L +++ A+ ++ + E L KE+A + G S Sbjct: 840 SRQLSGREQELEQARREAQ-RQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEE 898 Query: 258 P---KVQVEAIEGGALQ---KLLVILATEQPLTAKKKVLFALCSLLRHFPYAQRQFLKLG 311 +++ EA+EG + +L + A + L A+ + L L +L Sbjct: 899 ATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTG---------ELA 949 Query: 312 GLQVLRTLVQEKGTEVLAVRVVTLLYDLVTEKMFAEEEAELTQEMSPEKLQQYRQVHLLP 371 GL+ QEK +L +L+ +K+ + E E + ++ + L Sbjct: 950 GLRQQIIATQEK---------ASLDKELMAQKL-VQAEREAQASLREQRAAHEEDLQRLQ 999 Query: 372 GLWEQGWCEITAHLLALPEHDAREKVLQTLGVLLTTCRDRYRQD---PQLGRTLASLQAE 428 E W E+ A L RE+ + L L ++ ++ Q R L AE Sbjct: 1000 REKEAAWRELEAERAQLQSQLQREQ--EELLARLEAEKEELSEEIAALQQERDEGLLLAE 1057 Query: 429 YQVLASLELQDGEDEGYFQELLGSVNSL 456 + +L L++ E ++L+G+ +SL Sbjct: 1058 SEKQQALSLKESEKTALSEKLMGTRHSL 1085 >gi|4758648 kinesin family member 5B [Homo sapiens] Length = 963 Score = 36.6 bits (83), Expect = 0.049 Identities = 55/298 (18%), Positives = 125/298 (41%), Gaps = 33/298 (11%) Query: 92 RLNLQTGEREAKLQYEDKFRNNLKGKRLDINTNTYTSQDLKSALAKFKEGAEMESSK--- 148 +L Q +++ ++ + + LK + LD ++L ++ + ++ + E ++ Sbjct: 427 KLYKQLDDKDEEINQQSQLVEKLKTQMLD-------QEELLASTRRDQDNMQAELNRLQA 479 Query: 149 EDKARQAEVKRLFRPIEELKKDFDELNVVIETDMQIMVRLINKFNSSSSSLEEKIAALFD 208 E+ A + EVK + + +EEL ++D+ + +E + L ++ N S++L A L Sbjct: 480 ENDASKEEVKEVLQALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSATLASIDAELQK 539 Query: 209 L-EYYVHQMDNAQDL-------LSFGGLQVVINGLNSTEPLVKEYAAFVLGAAFSSNPKV 260 L E HQ A ++ L+ G+ V N + E F + + S K Sbjct: 540 LKEMTNHQKKRAAEMMASLLKDLAEIGIAVGNNDVKQPEGTGMIDEEFTVARLYISKMKS 599 Query: 261 QVEAIEGGALQKLLVILATEQPLTAKKKVLFALCSLLRHFPYAQRQFLKLGGLQVLRTLV 320 +V+ + Q + + + +K L A C L +Q + + L+ + Sbjct: 600 EVKTMVKRCKQLESTQTESNKKMEENEKEL-AACQL----RISQHEAKIKSLTEYLQNVE 654 Query: 321 QEK----------GTEVLAVRVVTLLYDLVTEKMFAEEEAELTQEMSPEKLQQYRQVH 368 Q+K E++ +R ++++ E + + A ++ +++Q +R+ H Sbjct: 655 QKKRQLEESVDALSEELVQLRAQEKVHEMEKEHLNKVQTANEVKQAVEQQIQSHRETH 712 >gi|170650672 Leber congenital amaurosis 5 [Homo sapiens] Length = 697 Score = 36.6 bits (83), Expect = 0.049 Identities = 30/130 (23%), Positives = 63/130 (48%), Gaps = 11/130 (8%) Query: 48 TKETERKETKAEEELDAEVLEVFHPTHEWQALQPGQAVPAGSHVRLNLQTGEREAKLQYE 107 ++E ER K ++ ++E+ + + + + +P + L + E L+ + Sbjct: 178 SQEKERATEKRVKDTESELFRTKFSLQKLKEISEARHLPERDDLAKKLVSAE----LKLD 233 Query: 108 DKFRNNLK-GKRLDINTNTYTSQDLKSALAKFKEGAEMESSKEDKARQAEVKRLFRPIEE 166 D R + K L+++TN++ Q LA+ K E+ E+K Q EV+RL+ ++E Sbjct: 234 DTERRIKELSKNLELSTNSFQRQ----LLAERKRA--YEAHDENKVLQKEVQRLYHKLKE 287 Query: 167 LKKDFDELNV 176 +++ D N+ Sbjct: 288 KERELDIKNI 297 >gi|170650670 Leber congenital amaurosis 5 [Homo sapiens] Length = 697 Score = 36.6 bits (83), Expect = 0.049 Identities = 30/130 (23%), Positives = 63/130 (48%), Gaps = 11/130 (8%) Query: 48 TKETERKETKAEEELDAEVLEVFHPTHEWQALQPGQAVPAGSHVRLNLQTGEREAKLQYE 107 ++E ER K ++ ++E+ + + + + +P + L + E L+ + Sbjct: 178 SQEKERATEKRVKDTESELFRTKFSLQKLKEISEARHLPERDDLAKKLVSAE----LKLD 233 Query: 108 DKFRNNLK-GKRLDINTNTYTSQDLKSALAKFKEGAEMESSKEDKARQAEVKRLFRPIEE 166 D R + K L+++TN++ Q LA+ K E+ E+K Q EV+RL+ ++E Sbjct: 234 DTERRIKELSKNLELSTNSFQRQ----LLAERKRA--YEAHDENKVLQKEVQRLYHKLKE 287 Query: 167 LKKDFDELNV 176 +++ D N+ Sbjct: 288 KERELDIKNI 297 >gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo sapiens] Length = 1940 Score = 36.2 bits (82), Expect = 0.064 Identities = 99/447 (22%), Positives = 166/447 (37%), Gaps = 67/447 (14%) Query: 31 SHQNLKEFALTNPEKSSTKETERKETKAEEELDAEVLEVFHPTHEWQALQPGQAVPAGSH 90 S + KE A E TK+ K +EL+ +++ + ++ Q V A S Sbjct: 843 SAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQL-----QVQAESE 897 Query: 91 VRLNLQTGEREAKLQYEDKFRNNLKGKRLDINTNTYTSQDLKSALAKFKEGAEMESSKED 150 NL E + KF+ L+ K ++ +++ + L K E E S Sbjct: 898 ---NLLDAEERCDQLIKAKFQ--LEAKIKEVTERAEDEEEINAELTAKKRKLEDECS--- 949 Query: 151 KARQAEVKRLFRPIEELKKDFDELNVV---IETDMQIMVRLINKFNSSSSSLEEKIAALF 207 ELKKD D+L + +E + + S L+E IA L Sbjct: 950 ---------------ELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKL- 993 Query: 208 DLEYYVHQMDNAQDLLSFGGLQVVINGLNSTEPLVKEYAAFVLGAAFSSNPKVQVE---- 263 E Q + Q L + +N LN T+ +++ L ++ K++V+ Sbjct: 994 TREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVE-DLESSLEQEKKLRVDLERN 1052 Query: 264 --AIEGG---ALQKLLVILATEQPLTAK-KKVLFALCSLLRHFPYAQR---QFLKLGGLQ 314 +EG A + +L + +Q L + KK F C L Q QF K ++ Sbjct: 1053 KRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQK--KIK 1110 Query: 315 VLRTLVQEKGTEVLAVRVVTLLYDLVTEKM---FAEEEAELTQEMSPEKLQQYRQVHLLP 371 L+ ++E E+ A R TEK +A E EL++ + Q+ L Sbjct: 1111 ELQARIEELEEEIEAERATR----AKTEKQRSDYARELEELSERLEEAGGVTSTQIELNK 1166 Query: 372 GLWEQGWCEITAHLLALPEHDAREKVLQTLGVLLTTCRDRYRQDPQLGRTLASLQAEYQV 431 + A L L D E LQ ++ + +LG + +LQ +V Sbjct: 1167 --------KREAEFLKL-RRDLEEATLQHEAMVAALRKKHADSVAELGEQIDNLQ---RV 1214 Query: 432 LASLELQDGEDEGYFQELLGSVNSLLK 458 LE + E + +L S+ S+ K Sbjct: 1215 KQKLEKEKSEFKLEIDDLSSSMESVSK 1241 >gi|7705415 hook homolog 1 [Homo sapiens] Length = 728 Score = 35.8 bits (81), Expect = 0.084 Identities = 45/195 (23%), Positives = 91/195 (46%), Gaps = 12/195 (6%) Query: 36 KEFALTNPEKSSTKETERKETKAEEELDAEVL-----EVF-HPTHEWQALQPGQAVPAGS 89 +E + ++ +T+ TK+ E L AE++ EVF HE + L+ Q Sbjct: 428 EELRCSQVQQDHLNQTDASATKSYENLAAEIMPVEYREVFIRLQHENKMLRLQQEGSENE 487 Query: 90 HVRLNLQTGEREAKLQYEDKFRNNLKGKRLDINTNTYTSQDLKSALAKFKEGAEMESSKE 149 + + E++ + E + L +R I +DL+ +L + +E ESS + Sbjct: 488 RIEELQEQLEQKHRKMNELETEQRLSKER--IRELQQQIEDLQKSLQEQGSKSEGESSSK 545 Query: 150 DKAR-QAEVKRLFRPIEELKKDFDELNVVIETDMQIMVRLINKFNSSSSSLEEKIAALFD 208 K + +A +++L EEL+K EL ++ D+ V+ IN+ ++ +E + A+ Sbjct: 546 LKQKLEAHMEKLTEVHEELQKK-QELIEDLQPDINQNVQKINELEAALQKKDEDMKAM-- 602 Query: 209 LEYYVHQMDNAQDLL 223 E Y ++ A++++ Sbjct: 603 EERYKMYLEKARNVI 617 >gi|29540566 armadillo repeat containing, X-linked 3 [Homo sapiens] Length = 379 Score = 35.4 bits (80), Expect = 0.11 Identities = 31/110 (28%), Positives = 52/110 (47%), Gaps = 5/110 (4%) Query: 141 GAEMESSKEDKARQAEVKRLFRPIEELKKDFDELNVVIETDMQIMVRLINKFNSSSSSLE 200 G E + +AR A R R +++ + V+ ++Q ++ L+ + + LE Sbjct: 83 GTEAGTRARARAR-ARATRARRAVQKRASPNSDDTVLSPQELQKVLCLV-EMSEKPYILE 140 Query: 201 EKIAALFDLEYYVHQMDNAQDLLSFGGLQVVINGLNSTEPLVKEYAAFVL 250 + AL + Y D +DL GGL +V LN+ +P+VKE A VL Sbjct: 141 AALIALGNNAAYAFNRDIIRDL---GGLPIVAKILNTRDPIVKEKALIVL 187 >gi|29540564 armadillo repeat containing, X-linked 3 [Homo sapiens] Length = 379 Score = 35.4 bits (80), Expect = 0.11 Identities = 31/110 (28%), Positives = 52/110 (47%), Gaps = 5/110 (4%) Query: 141 GAEMESSKEDKARQAEVKRLFRPIEELKKDFDELNVVIETDMQIMVRLINKFNSSSSSLE 200 G E + +AR A R R +++ + V+ ++Q ++ L+ + + LE Sbjct: 83 GTEAGTRARARAR-ARATRARRAVQKRASPNSDDTVLSPQELQKVLCLV-EMSEKPYILE 140 Query: 201 EKIAALFDLEYYVHQMDNAQDLLSFGGLQVVINGLNSTEPLVKEYAAFVL 250 + AL + Y D +DL GGL +V LN+ +P+VKE A VL Sbjct: 141 AALIALGNNAAYAFNRDIIRDL---GGLPIVAKILNTRDPIVKEKALIVL 187 >gi|7705274 armadillo repeat containing, X-linked 3 [Homo sapiens] Length = 379 Score = 35.4 bits (80), Expect = 0.11 Identities = 31/110 (28%), Positives = 52/110 (47%), Gaps = 5/110 (4%) Query: 141 GAEMESSKEDKARQAEVKRLFRPIEELKKDFDELNVVIETDMQIMVRLINKFNSSSSSLE 200 G E + +AR A R R +++ + V+ ++Q ++ L+ + + LE Sbjct: 83 GTEAGTRARARAR-ARATRARRAVQKRASPNSDDTVLSPQELQKVLCLV-EMSEKPYILE 140 Query: 201 EKIAALFDLEYYVHQMDNAQDLLSFGGLQVVINGLNSTEPLVKEYAAFVL 250 + AL + Y D +DL GGL +V LN+ +P+VKE A VL Sbjct: 141 AALIALGNNAAYAFNRDIIRDL---GGLPIVAKILNTRDPIVKEKALIVL 187 >gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo sapiens] Length = 1938 Score = 34.7 bits (78), Expect = 0.19 Identities = 43/189 (22%), Positives = 73/189 (38%), Gaps = 25/189 (13%) Query: 37 EFALTNPEKSSTKETERKETKAEEELDAEVLEVFHPTHEWQALQPGQAVPAGS------- 89 E LT EK TE K EE+ A + T E ++LQ Sbjct: 962 ELTLTKVEKEK-HATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDK 1020 Query: 90 -------HVRLNLQTGEREAKLQYEDKFRNNLKGKRLDINTNTYTSQDLKSALAKFKEGA 142 + +L QT + E L+ E K R +L+ + + + SQ+ L K+ Sbjct: 1021 VNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQI 1080 Query: 143 EME-SSKEDKARQAEVK---------RLFRPIEELKKDFDELNVVIETDMQIMVRLINKF 192 E + KE + Q + K + + I+EL+ +EL IE + + ++ + Sbjct: 1081 EEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQR 1140 Query: 193 NSSSSSLEE 201 + + LEE Sbjct: 1141 SDLARELEE 1149 >gi|118600973 RNA binding motif protein, X-linked 2 [Homo sapiens] Length = 322 Score = 34.7 bits (78), Expect = 0.19 Identities = 29/120 (24%), Positives = 57/120 (47%), Gaps = 12/120 (10%) Query: 43 PEKSSTKETERKETKAEEELDAEVLEVFHPTHEWQALQPGQAVPAGSHVRLNLQTGEREA 102 P K K+ + K+ K +E+ A+ E QA QP + P V+ TG ++ Sbjct: 154 PTKKHKKDKKEKKKKKKEKEKAD--------REVQAEQPSSSSPRRKTVKEKDDTGPKKH 205 Query: 103 KLQYEDKFRNN--LKGKRLDINTNTYT--SQDLKSALAKFKEGAEMESSKEDKARQAEVK 158 + ++ + + +G++L + Y+ ++DL+ L K K E +SS +AR+ + + Sbjct: 206 SSKNSERAQKSEPREGQKLPKSRTAYSGGAEDLERELKKEKPKHEHKSSSRREAREEKTR 265 >gi|68299795 chromodomain helicase DNA binding protein 1 [Homo sapiens] Length = 1710 Score = 34.7 bits (78), Expect = 0.19 Identities = 31/147 (21%), Positives = 60/147 (40%), Gaps = 12/147 (8%) Query: 46 SSTKETERKETKAEEELDAEVLEVFHPTHEWQALQPGQAVPAGSHVRLNLQTGER---EA 102 +S E + ++ ++ +EV H +WQ G +GS + + E Sbjct: 119 NSGSEEDSSSSEDSDDSSSEVKRKKHKDEDWQMSGSGSPSQSGSDSESEEEREKSSCDET 178 Query: 103 KLQYEDKFRNNLKGKRLDINTNTYTSQDLKSALAKFKEGAEMESSKED-------KARQA 155 + YE K N +K ++ + + + + + + +E + +ED RQA Sbjct: 179 ESDYEPK--NKVKSRKPQNRSKSKNGKKILGQKKRQIDSSEEDDDEEDYDNDKRSSRRQA 236 Query: 156 EVKRLFRPIEELKKDFDELNVVIETDM 182 V ++ EE+K D D+L V D+ Sbjct: 237 TVNVSYKEDEEMKTDSDDLLEVCGEDV 263 >gi|29294627 PTPRF interacting protein binding protein 1 isoform 1 [Homo sapiens] Length = 1005 Score = 34.3 bits (77), Expect = 0.24 Identities = 46/196 (23%), Positives = 86/196 (43%), Gaps = 39/196 (19%) Query: 49 KETERKETKAEEELDAEVLEVFHPTHEWQALQPGQAVPAGSHVRLNLQTGEREAKLQYED 108 +E K EE L E+L + E Q L + S+++L L E++ +L YED Sbjct: 142 EEHREKVNATEEMLQQELLS--RTSLETQKLDLMAEI---SNLKLKLTAVEKD-RLDYED 195 Query: 109 KFRNNLKGKRLDINTNTYTSQDLKSALAKFKEGAEMESSKEDKA--------RQAEVKRL 160 KFR+ +G +IN ++ S ++++ +++S+K++ A +++EVKRL Sbjct: 196 KFRDT-EGLIQEINDLRLKVSEMDSERLQYEK--KLKSTKDELASLKEQLEEKESEVKRL 252 Query: 161 FRPI---------------EELKKDFDELNVVIETDMQIMVRLINKFNSSSSSLEEKIAA 205 + E KK E N+ ++ ++ S ++ EEK Sbjct: 253 QEKLVCKMKGEGVEIVDRDENFKKKLKEKNIEVQ-------KMKKAVESLMAANEEKDRK 305 Query: 206 LFDLEYYVHQMDNAQD 221 + DL +++ QD Sbjct: 306 IEDLRQCLNRYKKMQD 321 >gi|4758650 kinesin family member 5C [Homo sapiens] Length = 957 Score = 33.9 bits (76), Expect = 0.32 Identities = 43/215 (20%), Positives = 95/215 (44%), Gaps = 22/215 (10%) Query: 96 QTGEREAKLQYEDKFRNNLKGKRLDINTNTYTSQDLKSALAKFKEGAEMESSK---EDKA 152 Q +++ ++ + + LK + LD +L ++ + E + E ++ E++A Sbjct: 427 QLDDKDDEINQQSQLAEKLKQQMLD-------QDELLASTRRDYEKIQEELTRLQIENEA 479 Query: 153 RQAEVKRLFRPIEELKKDFDELNVVIETDMQIMVRLINKFNSSSSSLEEKIAALFDL-EY 211 + EVK + + +EEL ++D+ + +E + +L ++ +++L L L E Sbjct: 480 AKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQLQEL 539 Query: 212 YVHQMDNAQDLLS-----FGGLQVVINGLNSTEPLVKEYAA----FVLGAAFSSNPKVQV 262 HQ A ++L+ G + +I G N + L F + + S K +V Sbjct: 540 SNHQKKRATEILNLLLKDLGEIGGII-GTNDVKTLADVNGVIEEEFTMARLYISKMKSEV 598 Query: 263 EAIEGGALQKLLVILATEQPLTAKKKVLFALCSLL 297 +++ + Q + + + + A ++ L A C LL Sbjct: 599 KSLVNRSKQLESAQMDSNRKMNASEREL-AACQLL 632 Score = 33.9 bits (76), Expect = 0.32 Identities = 42/171 (24%), Positives = 74/171 (43%), Gaps = 18/171 (10%) Query: 45 KSSTKETERKETKAEEELDAEVLEVFHPTHEWQALQPGQAVPAGSHVRLNLQTG-----E 99 +S+ ++ RK +E EL A ++ HE + + R L+ E Sbjct: 609 ESAQMDSNRKMNASERELAA--CQLLISQHEAKIKSLTDYMQNMEQKRRQLEESQDSLSE 666 Query: 100 REAKLQYEDKFRN-NLKGKRLDINTNTYTSQDLKSALAKFKEGAEMESSKEDKARQAEVK 158 AKL+ ++K + + K + T ++++K AL + +MES +E A Q ++ Sbjct: 667 ELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQ-----QMESHRE--AHQKQLS 719 Query: 159 RLFRPIEELKKDFDE---LNVVIETDMQIMVRLINKFNSSSSSLEEKIAAL 206 RL IEE +K DE LN ++ + + + NK E K+ L Sbjct: 720 RLRDEIEEKQKIIDEIRDLNQKLQLEQEKLSSDYNKLKIEDQEREMKLEKL 770 >gi|41281683 disabled homolog 2 interacting protein isoform 2 [Homo sapiens] Length = 1065 Score = 33.9 bits (76), Expect = 0.32 Identities = 30/103 (29%), Positives = 49/103 (47%), Gaps = 4/103 (3%) Query: 136 AKFKEGAE-MESSKEDKARQAE--VKRLFRPIEELKKDFDELNVVIETDMQIMVRLINKF 192 A+ +EG E + +EDK Q + + RL EELKKD E+ +++ +I+ + Sbjct: 955 ARLEEGEERLRRQQEDKDIQMKGIISRLMSVEEELKKDHAEMQAAVDSKQKIIDAQEKRI 1014 Query: 193 NSSSSSLEEKIAALFDL-EYYVHQMDNAQDLLSFGGLQVVING 234 S ++ ++AL L E Y Q N + LQ+ NG Sbjct: 1015 ASLDAANARLMSALTQLKERYSMQARNGISPTNPTKLQITENG 1057 >gi|211059433 coiled-coil domain containing 79 [Homo sapiens] Length = 727 Score = 33.9 bits (76), Expect = 0.32 Identities = 34/144 (23%), Positives = 60/144 (41%), Gaps = 5/144 (3%) Query: 178 IETDMQIMVRLINKFNSSSSSLEEKIAALFDLEYYVHQMDNAQDLL-SFGGLQVVINGLN 236 ++TD+ +++ + ++ S +E AL + Q NA GGL V N Sbjct: 12 MKTDLNLLLECLKYQMDNAFSQKE---ALVTIHSICQQNSNASVYFREIGGLMFVKNLAK 68 Query: 237 STE-PLVKEYAAFVLGAAFSSNPKVQVEAIEGGALQKLLVILATEQPLTAKKKVLFALCS 295 S+E +VKE A + LGA N Q + L L+ + + K+ ++ + Sbjct: 69 SSEHSMVKEAALYTLGAIAEKNVYCQQTLCTSELFEDLTWFLSNDSNINLKRMSVYVILV 128 Query: 296 LLRHFPYAQRQFLKLGGLQVLRTL 319 L+ + Q + G + VL L Sbjct: 129 LVSNNRTGQTLVRETGCITVLSRL 152 >gi|148839339 nexilin (F actin binding protein) [Homo sapiens] Length = 675 Score = 33.9 bits (76), Expect = 0.32 Identities = 42/171 (24%), Positives = 77/171 (45%), Gaps = 24/171 (14%) Query: 44 EKSSTKETERKETKAEEELDAEVLEVFHPTHEWQALQPGQAVPAGSHVRLNLQTG----- 98 ++ S KE + ++E+++E + ++L PG+ + Q Sbjct: 215 QRPSLKEAKCLSLVMDDEIESEAKK--------ESLSPGKLKLTFEELERQRQENRKKQA 266 Query: 99 EREAKLQYEDKFRNNLKGKRLDINTNTYTSQDLKSALAKFKEGA------EMESSK-EDK 151 E EA+ + E++ R + +R +N + +QD ++ G EME + ED+ Sbjct: 267 EEEARKRLEEEKRAFEEARRQMVNEDE-ENQDTAKIFKGYRPGKLKLSFEEMERQRREDE 325 Query: 152 ARQAEVKRLFRPIEELKKDFDEL--NVVIETDMQIMVRLINKFNSSSSSLE 200 R+AE + R IEE KK F E N+V++ D M + I++ + LE Sbjct: 326 KRKAE-EEARRRIEEEKKAFAEARRNMVVDDDSPEMYKTISQEFLTPGKLE 375 >gi|37588869 ring finger protein 123 [Homo sapiens] Length = 1314 Score = 33.5 bits (75), Expect = 0.42 Identities = 36/141 (25%), Positives = 63/141 (44%), Gaps = 9/141 (6%) Query: 260 VQVEAIEGGALQKLLVILATEQPLTAKKKVLFALCSLLRHF-PYAQRQFLKLGGLQVLRT 318 V+++ +EG L K +++ L + VL L + HF P ++ +L L Sbjct: 288 VELDPVEGRLLDKE----SSKWRLRGQPTVLLTLAHIFHHFAPLLRKVYLVEAVLMSFLL 343 Query: 319 LVQEKGTEVLAVRVVTLLYDLVTEKMFAEEEAELTQEMSPEKLQQYRQVHLLPGLWEQ-G 377 + EKGT A VV + DL+ M E + +++ L+ YR ++P L Q Sbjct: 344 GIVEKGTPTQAQSVVHQVLDLLWLFMEDYEVQDCLKQLMMSLLRLYRFSPIVPDLGLQIH 403 Query: 378 WCEITAHLLALPEHDAREKVL 398 + +T +A+ H+ K L Sbjct: 404 YLRLT---IAILRHEKSRKFL 421 >gi|150170718 zinc finger protein 292 [Homo sapiens] Length = 2723 Score = 33.5 bits (75), Expect = 0.42 Identities = 32/176 (18%), Positives = 71/176 (40%), Gaps = 10/176 (5%) Query: 39 ALTNPEKSSTKETERKETKAEEELDAEVLEVFHPTHEWQALQPGQAVPAGSHVRLNLQTG 98 ALTN + K K+ K E++ V + + +P + V G +Q Sbjct: 2071 ALTNTQTKGRKIRRHKKEKEEKKRKKPVSQSLEFPTRYSPYRPYRCVHQGCFAAFTIQ-- 2128 Query: 99 EREAKLQYEDKFRNNLKGKRLDINTNTYTSQDLKSALAKFKEGAEMESSKEDKARQAEVK 158 + L Y+ +++L ++ + ++ + K ++ KE + + ++ Sbjct: 2129 -QNLILHYQAVHKSDLPAFSAEVEEESEAGKESEETETK-------QTLKEFRCQVSDCS 2180 Query: 159 RLFRPIEELKKDFDELNVVIETDMQIMVRLINKFNSSSSSLEEKIAALFDLEYYVH 214 R+F+ I L + + +L+ + +++ M ++ LE K + L Y VH Sbjct: 2181 RIFQAITGLIQHYMKLHEMTPEEIESMTASVDVGKFPCDQLECKSSFTTYLNYVVH 2236 >gi|7662162 ALEX2 protein [Homo sapiens] Length = 632 Score = 33.5 bits (75), Expect = 0.42 Identities = 26/110 (23%), Positives = 52/110 (47%), Gaps = 6/110 (5%) Query: 143 EMESSKEDKARQAEVKRLFRPIEELKKDFD-ELNVVIET-DMQIMVRLINKFNSSSSSLE 200 + ES + + R RP+ K+ F E++ ++ D++ ++ L+ K S ++ Sbjct: 347 DTESDSDSEPETQRRGRGRRPVAMQKRPFPYEIDEILGVRDLRKVLALLQK--SDDPFIQ 404 Query: 201 EKIAALFDLEYYVHQMDNAQDLLSFGGLQVVINGLNSTEPLVKEYAAFVL 250 + AL L + N + + GGL ++ N +N T+P +KE A + Sbjct: 405 Q--VALLTLSNNANYSCNQETIRKLGGLPIIANMINKTDPHIKEKALMAM 452 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.316 0.132 0.365 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,791,319 Number of Sequences: 37866 Number of extensions: 658114 Number of successful extensions: 3123 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 25 Number of HSP's successfully gapped in prelim test: 92 Number of HSP's that attempted gapping in prelim test: 3014 Number of HSP's gapped (non-prelim): 210 length of query: 461 length of database: 18,247,518 effective HSP length: 106 effective length of query: 355 effective length of database: 14,233,722 effective search space: 5052971310 effective search space used: 5052971310 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.