BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|239756385 PREDICTED: similar to hCG1991431 [Homo sapiens] (232 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|239756385 PREDICTED: similar to hCG1991431 [Homo sapiens] 495 e-140 gi|38683827 ADAM metallopeptidase with thrombospondin type 1 mot... 370 e-103 gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens] 50 2e-06 gi|116284392 mucin 2 precursor [Homo sapiens] 49 4e-06 gi|160707881 formin 2 [Homo sapiens] 47 1e-05 gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens] 45 4e-05 gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom... 45 4e-05 gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom... 45 4e-05 gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap... 45 4e-05 gi|153792074 proline rich 12 [Homo sapiens] 45 4e-05 gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 45 7e-05 gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 45 7e-05 gi|18079216 CASK interacting protein 1 [Homo sapiens] 44 9e-05 gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 44 2e-04 gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 44 2e-04 gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 44 2e-04 gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 43 2e-04 gi|56118221 amyloid beta (A4) precursor protein-binding, family ... 43 2e-04 gi|14602439 Williams Beuren syndrome chromosome region 14 isofor... 43 3e-04 gi|14602437 Williams Beuren syndrome chromosome region 14 isofor... 43 3e-04 gi|14602435 Williams Beuren syndrome chromosome region 14 isofor... 43 3e-04 gi|14602433 Williams Beuren syndrome chromosome region 14 isofor... 43 3e-04 gi|55750053 atrophin-1 [Homo sapiens] 42 4e-04 gi|55750041 atrophin-1 [Homo sapiens] 42 4e-04 gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] 42 4e-04 gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] 42 4e-04 gi|41281612 zinc finger protein 828 [Homo sapiens] 42 6e-04 gi|31324577 molecule interacting with Rab13 [Homo sapiens] 42 6e-04 gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 41 8e-04 gi|24308227 zinc finger protein 687 [Homo sapiens] 41 8e-04 >gi|239756385 PREDICTED: similar to hCG1991431 [Homo sapiens] Length = 232 Score = 495 bits (1275), Expect = e-140 Identities = 232/232 (100%), Positives = 232/232 (100%) Query: 1 MACRCLPPLRAKMISQLARTARASCPLHGRTGPMRFSNDEEPEGCGAPHLPPRPSPTLPT 60 MACRCLPPLRAKMISQLARTARASCPLHGRTGPMRFSNDEEPEGCGAPHLPPRPSPTLPT Sbjct: 1 MACRCLPPLRAKMISQLARTARASCPLHGRTGPMRFSNDEEPEGCGAPHLPPRPSPTLPT 60 Query: 61 LYPVSSTHSSPSPDVAELWTGGTVAWESALEGGLGPVDSELWPTVGVASLPPPPIAPLPE 120 LYPVSSTHSSPSPDVAELWTGGTVAWESALEGGLGPVDSELWPTVGVASLPPPPIAPLPE Sbjct: 61 LYPVSSTHSSPSPDVAELWTGGTVAWESALEGGLGPVDSELWPTVGVASLPPPPIAPLPE 120 Query: 121 MKGNDSPLQPGTPTFPTPGPGLWDLQTVAVWGTFLPTTLTDLGHTPEPALNPGPKGQPES 180 MKGNDSPLQPGTPTFPTPGPGLWDLQTVAVWGTFLPTTLTDLGHTPEPALNPGPKGQPES Sbjct: 121 MKGNDSPLQPGTPTFPTPGPGLWDLQTVAVWGTFLPTTLTDLGHTPEPALNPGPKGQPES 180 Query: 181 LSPEVPLSSRLLSMPAWDSPANSHRAPETQPLPPSLAEAGPPTDPLVVRNAG 232 LSPEVPLSSRLLSMPAWDSPANSHRAPETQPLPPSLAEAGPPTDPLVVRNAG Sbjct: 181 LSPEVPLSSRLLSMPAWDSPANSHRAPETQPLPPSLAEAGPPTDPLVVRNAG 232 >gi|38683827 ADAM metallopeptidase with thrombospondin type 1 motif, 7 preproprotein [Homo sapiens] Length = 1686 Score = 370 bits (950), Expect = e-103 Identities = 178/207 (85%), Positives = 183/207 (88%), Gaps = 1/207 (0%) Query: 26 PLHGRTGPMRFSNDEEPEGCGAPHLPPRPSPTLPTLYPVSSTHSSPSPDVAELWTGGTVA 85 P RT + F +DEEP+G GAPHLPPRPS TLP L PV STHSSPSPDVAELWTGGTVA Sbjct: 1209 PWRDRTNEV-FKDDEEPKGRGAPHLPPRPSSTLPPLSPVGSTHSSPSPDVAELWTGGTVA 1267 Query: 86 WESALEGGLGPVDSELWPTVGVASLPPPPIAPLPEMKGNDSPLQPGTPTFPTPGPGLWDL 145 WE ALEGGLGPVDSELWPTVGVASL PPPIAPLPEMK DS L+PGTP+FPTPGPG WDL Sbjct: 1268 WEPALEGGLGPVDSELWPTVGVASLLPPPIAPLPEMKVRDSSLEPGTPSFPTPGPGSWDL 1327 Query: 146 QTVAVWGTFLPTTLTDLGHTPEPALNPGPKGQPESLSPEVPLSSRLLSMPAWDSPANSHR 205 QTVAVWGTFLPTTLT LGH PEPALNPGPKGQPESLSPEVPLSSRLLS PAWDSPANSHR Sbjct: 1328 QTVAVWGTFLPTTLTGLGHMPEPALNPGPKGQPESLSPEVPLSSRLLSTPAWDSPANSHR 1387 Query: 206 APETQPLPPSLAEAGPPTDPLVVRNAG 232 PETQPL PSLAEAGPP DPLVVRNAG Sbjct: 1388 VPETQPLAPSLAEAGPPADPLVVRNAG 1414 Score = 34.3 bits (77), Expect = 0.093 Identities = 54/198 (27%), Positives = 69/198 (34%), Gaps = 32/198 (16%) Query: 34 MRFSNDEEPE----GCGAPHLPPRPSPTLP-TLYPVSSTHSSPSPDVAELWTGGTVAWES 88 + + EEP+ G G PP P P T PV +T + + Sbjct: 1076 LSYGPSEEPDLDLAGTGDRTPPPHSHPAAPSTGSPVPATEPPAAKE-------------- 1121 Query: 89 ALEGGLGPVDSELWPTVGVASLPPPPIAPLPEMKGNDSPLQPGTPTFPTPGPGLWDLQTV 148 EG LGP WP+ S PPPP P GN PL P TP G DL Sbjct: 1122 --EGVLGPWSPSPWPSQAGRS-PPPPSEQTP---GN--PLINFLPEEDTP-IGAPDLGLP 1172 Query: 149 AVWGTFLPTTLTDLGHTPEPALNPGPKGQPESLSPEVPLSSRLLSMPAWDSPANSHRAPE 208 ++ + T TPE + N P G+ P R + D AP Sbjct: 1173 SLSWPRVSTDGLQTPATPE-SQNDFPVGKDSQSQLPPPWRDRTNEVFKDDEEPKGRGAPH 1231 Query: 209 TQPLPPSLAEAGPPTDPL 226 LPP + PP P+ Sbjct: 1232 ---LPPRPSSTLPPLSPV 1246 >gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens] Length = 1711 Score = 50.1 bits (118), Expect = 2e-06 Identities = 55/200 (27%), Positives = 75/200 (37%), Gaps = 25/200 (12%) Query: 48 PHLPPRPSPTLPTLY----PVSSTHSSPSPDVAELWTGGTVAWESALEGGLG-------- 95 P L P P P++PTL P+S + S P A G V + L Sbjct: 256 PALAPAP-PSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPAPAPLSVPVSAPPL 314 Query: 96 -----PVDSELWPTVGVASLPPPPIAPLPEMKGNDSPLQPGTPTFPTPGPGLWDLQTVAV 150 PV PT+ +A +P P +AP+P +P P P PTP P T + Sbjct: 315 ALIQAPVPPSA-PTLVLAPVPTPVLAPMPASTPPAAPAPPSVP-MPTPTPSSGPPSTPTL 372 Query: 151 WGTFLPTTLTDLGHTPEPALNPGPKGQPESLSPEVPLSSRL---LSMPAWDSPANSHRAP 207 F PT + TP P P P P + +P S+ + S+ PA A Sbjct: 373 IPAFAPTPVP--APTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQAPAM 430 Query: 208 ETQPLPPSLAEAGPPTDPLV 227 + PL P+ PLV Sbjct: 431 QKVPLSFQPGTVLTPSQPLV 450 Score = 41.2 bits (95), Expect = 8e-04 Identities = 39/135 (28%), Positives = 54/135 (40%), Gaps = 26/135 (19%) Query: 111 PPPPIAPLPEMKGNDSPLQPGTPTFPTPGPGLWDLQTVAVWGTFLPTTLTDLGHTPEPAL 170 P PP+AP+P + +P P PT + L +V V +P + G P A Sbjct: 248 PSPPLAPVPAL----APAPPSVPTLISDSNPLSVSASVLVP---VPASAPPSGPVPLSAP 300 Query: 171 NPGPKGQPESLSP------EVPLSSRLL-----------SMPAWDSPANSHRAPETQPLP 213 P P P S P VP S+ L MPA PA AP + P+P Sbjct: 301 APAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAP--APPSVPMP 358 Query: 214 PSLAEAGPPTDPLVV 228 +GPP+ P ++ Sbjct: 359 TPTPSSGPPSTPTLI 373 >gi|116284392 mucin 2 precursor [Homo sapiens] Length = 5179 Score = 48.9 bits (115), Expect = 4e-06 Identities = 48/197 (24%), Positives = 65/197 (32%), Gaps = 7/197 (3%) Query: 31 TGPMRFSNDEEPEGCGAPHLPPRPSPTLPTLYPVSSTHSS-PSPDVAELWTGGTVAWESA 89 T P + P LPP +P+ PT + ++ PSP + T S Sbjct: 1397 TTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSP 1456 Query: 90 LEGGLGPVDSELWPTVGVASLPPPPIAPLPEMKGNDSPLQPGTPTFPTPGPGLWDLQTVA 149 P+ + PP P P +P TP+ PT P T Sbjct: 1457 PISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTT 1516 Query: 150 VWGTFLPTTLTDLGHTPEPALNPGPKGQPESLSPEVPLSSRLLSMPAWDSP---ANSHRA 206 + T P+ T TP P P P P + P S+ L SP + Sbjct: 1517 LPPTTTPSPPTTTTTTPPPTTTPSP---PTTTPITPPTSTTTLPPTTTPSPPPTTTTTPP 1573 Query: 207 PETQPLPPSLAEAGPPT 223 P T P PP+ PPT Sbjct: 1574 PTTTPSPPTTTTPSPPT 1590 Score = 45.1 bits (105), Expect = 5e-05 Identities = 44/180 (24%), Positives = 59/180 (32%), Gaps = 25/180 (13%) Query: 48 PHLPPRPSPTLPTLYPVSSTH----SSPSPDVAELWTGGTVAWESALEGGLGPVDSELWP 103 P P P T P P S+T ++PSP T S P + P Sbjct: 1535 PTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSP------PTTTTPSP 1588 Query: 104 TVGVASLPPPPIAPLPEMKGNDSPLQPGTPTFPTPGPGLWDLQTVAVWGTFLPTTLTDLG 163 + PPP P P +P TP+ PT P T + T P+ Sbjct: 1589 PTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTT 1648 Query: 164 HTPEPALNPGPKGQPESLSPEVPLSSRLLSMPAWDSPANSHRAPETQPLPPSLAEAGPPT 223 TP P P P P + +P P+++ + P T P P PPT Sbjct: 1649 TTPPPTTTPSP---PTTTTPSPPITT------------TTTPPPTTTPSSPITTTPSPPT 1693 Score = 40.4 bits (93), Expect = 0.001 Identities = 41/159 (25%), Positives = 62/159 (38%), Gaps = 27/159 (16%) Query: 52 PRPSPT---LPTLYPVSSTHS-SPSPDVAELWTGGTVAWESALEGGLGPVDSELWPTVGV 107 P P+PT PT P+++T + +P+P TG P + P + Sbjct: 4163 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGP-------------PTHTSTAPIAEL 4209 Query: 108 ASLPPPPIAPLPEM-KGNDSPLQPGTPTFPTPGPGLWDLQTVAVWGTFLPTTLTDLGHT- 165 + PPP + P+ + SPL T T P + ++ + A T T T GHT Sbjct: 4210 TTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAI-EMTSTAPPSTPTAPTTTSGGHTL 4268 Query: 166 -PEPALNPGPKGQPE------SLSPEVPLSSRLLSMPAW 197 P P+ P G P S S P + + + AW Sbjct: 4269 SPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAW 4307 Score = 40.0 bits (92), Expect = 0.002 Identities = 45/181 (24%), Positives = 58/181 (32%), Gaps = 53/181 (29%) Query: 48 PHLPPRPSPTL-----PTLYPVSSTHSSPSPDVAELWTGGTVAWESALEGGLGPVDSELW 102 P P P PT PT P T ++PSP + T S+ P+ + Sbjct: 1637 PTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSS------PITTTPS 1690 Query: 103 PTVGVASLPPPPIAPLPEMKGNDSPLQPGTPTFPTPGPGLWDLQTVAVWGTFLPTTLTDL 162 P + P P P + +P TP+ P PTT+T Sbjct: 1691 PPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPP-------------------PTTMT-- 1729 Query: 163 GHTPEPALNPGPKGQPESLSPEVPLSSRLLSMPAWDSPANSHRAPETQPLPPSLAEAGPP 222 TP P P P + P SS L T PLPPS+ PP Sbjct: 1730 --TPSPTTTPSPPTTTMTTLPPTTTSSPL----------------TTTPLPPSIT---PP 1768 Query: 223 T 223 T Sbjct: 1769 T 1769 Score = 32.3 bits (72), Expect = 0.35 Identities = 32/128 (25%), Positives = 40/128 (31%), Gaps = 12/128 (9%) Query: 102 WPTVGVASLPPPPIAPLPEMKGNDSPLQPGTPTFP---TPGPGLWDLQTVAVWGTFLPTT 158 WP + P PP SP T T P TP P T T P Sbjct: 1390 WPMDKCITTPSPPTT-------TPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPI 1442 Query: 159 LTDLGHTPEPALNPGPKGQPESLSPEVPLSSRLLSMPAWDSPANSHRAPETQPLPPSLAE 218 T TP P P P + P S + P+ + S T PP+ Sbjct: 1443 TTTT--TPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTP 1500 Query: 219 AGPPTDPL 226 + P T P+ Sbjct: 1501 SPPTTTPI 1508 >gi|160707881 formin 2 [Homo sapiens] Length = 1722 Score = 47.0 bits (110), Expect = 1e-05 Identities = 59/200 (29%), Positives = 73/200 (36%), Gaps = 26/200 (13%) Query: 44 GCGAPHLPPRPSPTLPTLYPVSSTHSSPSPDVAELWTGGTVAWESALEG-GLGPVDSELW 102 G G P PP P +P P+ P P + G + L G G+ P Sbjct: 1060 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP----GAGIPPPPPLPGVGIPPP----- 1110 Query: 103 PTVGVASLPPPP------IAPLPEMKGNDSPLQPGTPTF------PTPGPGLWDLQTVAV 150 P + A +PPPP I P P + G P P P P PG G+ + Sbjct: 1111 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPG 1170 Query: 151 WGTFLPTTLTDLGHTPEPALNPGPKGQPESLSP--EVPLSSRLLSMPAWDSPANSHRAPE 208 G P L +G P P L PG P P +P L M +PA P Sbjct: 1171 AGIPPPPPLPGVGIPPPPPL-PGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPG 1229 Query: 209 TQ-PLPPSLAEAGPPTDPLV 227 T P PP L +GPP P V Sbjct: 1230 TGIPPPPLLPVSGPPLLPQV 1249 Score = 43.5 bits (101), Expect = 2e-04 Identities = 58/199 (29%), Positives = 68/199 (34%), Gaps = 29/199 (14%) Query: 44 GCGAPHLPPRPSPTLPTLYPVSSTHSSPSPDVAELWTGGTVAWESALEGGLGPVDSELWP 103 G G P PP P + L P+ P P + G + L G P L P Sbjct: 917 GAGIPPPPPLPGAGILPLPPLPGAGIPPPPPL----PGAAIPPPPPLPGAGIP----LPP 968 Query: 104 TVGVASLPPPPIAPLPEMKGNDSPLQPGT---PTFPTPGPGLWDLQTVAVWGTFLPTTLT 160 + A +PPPP PLP P PG P P PG G+ + G P L Sbjct: 969 PLPGAGIPPPP--PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1026 Query: 161 DLGHTPEPAL-----NPGPKGQPESLSPEVPLSSRLLSMPAWDSPANSHRAPETQPL--- 212 G P P L P P + P PL + P P P PL Sbjct: 1027 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP---PPLPGAGIPPPPPLPGA 1083 Query: 213 ----PPSLAEAG-PPTDPL 226 PP L AG PP PL Sbjct: 1084 GIPPPPPLPGAGIPPPPPL 1102 Score = 42.7 bits (99), Expect = 3e-04 Identities = 61/211 (28%), Positives = 73/211 (34%), Gaps = 43/211 (20%) Query: 44 GCGAPHLPPRPSPTLPTL--------YPVSSTHSSPSPDVAELWTGGTVAWESALEG-GL 94 G P PP P T+PTL P+ T P P G + L G G+ Sbjct: 874 GMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPP--LPGAGIPPPPPLPGAGI 931 Query: 95 GPVDSELWPTVGVASLPPPP------IAPLPEMKGNDSPLQPGTPTFPTPGPGLWDLQTV 148 P+ P + A +PPPP I P P + G PL P P PG G+ + Sbjct: 932 LPL-----PPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPP-----PLPGAGIPPPPPL 981 Query: 149 AVWGTFLPTTLTDLGHTPEPAL-----NPGPKGQPESLSPEVPLSSRLLSMPAWDSPANS 203 G P L G P P L P P + P PL + P P Sbjct: 982 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP---PPLPG 1038 Query: 204 HRAPETQPL-------PPSLAEAG-PPTDPL 226 P PL PP L AG PP PL Sbjct: 1039 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1069 Score = 42.4 bits (98), Expect = 3e-04 Identities = 56/192 (29%), Positives = 67/192 (34%), Gaps = 26/192 (13%) Query: 44 GCGAPHLPPRPSPTLPTLYPVSSTHSSPSPDVAELWTGGTVAWESALEG-GLGPVDSELW 102 G G P PP P +P P+ P P + G + L G G+ P Sbjct: 961 GAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPL----PGAGIPPPPPLPGAGIPPP----- 1011 Query: 103 PTVGVASLPPPPIAPLPEMKGNDSPLQPGT---PTFPTPGPGLWDLQTVAVWGTFLPTTL 159 P + A +PPPP PLP P PG P P PG G+ + G P L Sbjct: 1012 PPLPGAGIPPPP--PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1069 Query: 160 TDLGHTPEPALN----PGPKGQPESLSPEVPLSSRLLSMPAWDSPANSHRAPETQPLPPS 215 G P P L P P P + P P +P P P PP Sbjct: 1070 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP------PLPGVGIPPPPPLPGAGIPPPPP 1123 Query: 216 LAEAG-PPTDPL 226 L AG PP PL Sbjct: 1124 LPGAGIPPPPPL 1135 Score = 42.4 bits (98), Expect = 3e-04 Identities = 56/188 (29%), Positives = 67/188 (35%), Gaps = 18/188 (9%) Query: 44 GCGAPHLPPRPSPTLPTLYPVSSTHSSPSPDVAELWTGGTVAWESALEG-GLGPVDSELW 102 G G P PP P +P P+ P P + G + L G G+ P Sbjct: 972 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL----PGAGIPPPPPLPGAGIPPP----- 1022 Query: 103 PTVGVASLPPPPIAPLPEMKGNDSPLQPGT---PTFPTPGPGLWDLQTVAVWGTFLPTTL 159 P + A +PPPP PLP P PG P P PG G+ + G P L Sbjct: 1023 PPLPGAGIPPPP--PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1080 Query: 160 TDLGHTPEPALNPGPKGQPESLSPEVPLSSRLLSMPAWDSPANSHRAPETQPLPPSLAEA 219 G P P L PG P P V + +P P P PP L A Sbjct: 1081 PGAGIPPPPPL-PGAGIPPPPPLPGVGIPPP-PPLPGAGIPPPPPLPGAGIPPPPPLPGA 1138 Query: 220 G-PPTDPL 226 G PP PL Sbjct: 1139 GIPPPPPL 1146 Score = 35.8 bits (81), Expect = 0.032 Identities = 39/139 (28%), Positives = 50/139 (35%), Gaps = 23/139 (16%) Query: 44 GCGAPHLPPRPSPTLPTLYPVSSTHSSPSPDVAELWTGGTVAWESALEGGLGPVDSELWP 103 G G P PP P +P P+ P P + G + L G P L P Sbjct: 1126 GAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPL----PGAGIPPPPPLPGAGIPPPPPL-P 1180 Query: 104 TVGV--------ASLPPPP------IAPLPEMKGNDSPLQPGTPTFPTPGPGLWDLQTVA 149 VG+ +PPPP I P P + G P P P P PG G+ + Sbjct: 1181 GVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAP-APPLPPPGTGIPPPPLLP 1239 Query: 150 VWGTFLPTTLTDLGHTPEP 168 V G P L +G + P Sbjct: 1240 VSG---PPLLPQVGSSTLP 1255 Score = 35.4 bits (80), Expect = 0.042 Identities = 43/155 (27%), Positives = 58/155 (37%), Gaps = 28/155 (18%) Query: 44 GCGAPHLPPRPSPTLPTLYPVSSTHSSPSPDVAEL-------WTGGTVAWESALEG-GLG 95 G G P PP P +P P+ P P + + G + L G G+ Sbjct: 1159 GAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIP 1218 Query: 96 PVDSELWPTVGVASLPPPPIAPLPEMKGNDSPLQP--GTPTFPTPGPGLWDLQTVAVWGT 153 P + P G +PPPP+ P+ + PL P G+ T PTP Q Sbjct: 1219 PAPAPPLPPPG-TGIPPPPLLPV-----SGPPLLPQVGSSTLPTP-------QVCGFLPP 1265 Query: 154 FLPTTLTDLGHTPEPALNPGPKGQP-ESLSPEVPL 187 LP+ L LG + G + QP E P PL Sbjct: 1266 PLPSGLFGLGMNQD----KGSRKQPIEPCRPMKPL 1296 Score = 28.9 bits (63), Expect = 3.9 Identities = 36/134 (26%), Positives = 50/134 (37%), Gaps = 36/134 (26%) Query: 120 EMKGNDSPLQPGTPTFPTPG-------------------PGLWDLQTVAVWGTFLPTTLT 160 +++G + P P T P PG PG D + + LP +L Sbjct: 225 QLQGAEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLA 284 Query: 161 DLGHTPEPALNPGPKGQPESLSPEVPLSSRLLSMPAWDSPANSHRAPETQPLPPSLAEAG 220 EP P P G P S +P +P + A DSP+++ P P EAG Sbjct: 285 --AEPREPQQPPSPGGLPVSEAPSLPAA----QPAAKDSPSST-----AFPFP----EAG 329 Query: 221 PPTDP--LVVRNAG 232 P + VR AG Sbjct: 330 PGEEAAGAPVRGAG 343 >gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens] Length = 2089 Score = 45.4 bits (106), Expect = 4e-05 Identities = 53/198 (26%), Positives = 75/198 (37%), Gaps = 26/198 (13%) Query: 38 NDEEPEGCGAPHLPPRPSPTLPTLYPVSSTHSSPSPDVAELW-----TGGTVAWESALEG 92 + E P+ C P +P P+P L S H +P P ++ L T + + E Sbjct: 1030 DQESPDACLPPTVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRKTRQDGSQEA 1089 Query: 93 GLGPVDSELWPTVGVASLPPPPIAPLPEMKGNDSPLQ---PGTPTFPTPGPGLWDLQTVA 149 P+ SEL P P P+++ S P T P P P Q V Sbjct: 1090 PEAPLSSEL-----------EPFHPKPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVT 1138 Query: 150 VWGTFLPT---TLTDLGHTPEPALNPGPKGQPESLSPEVPLSSRLLSMPAWDSPANSH-R 205 T T T TPEP + P+ QP S S + P++S S + S + Sbjct: 1139 PKPTSQATRSRTNRSSVKTPEPVVPTAPELQP-STSTDQPVTSEPTSQVTRGRKSRSSVK 1197 Query: 206 APETQPLPPSLAEAGPPT 223 PET + P+ E P T Sbjct: 1198 TPET--VVPTALELQPST 1213 >gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo sapiens] Length = 1188 Score = 45.4 bits (106), Expect = 4e-05 Identities = 56/194 (28%), Positives = 71/194 (36%), Gaps = 25/194 (12%) Query: 41 EPEGCGAPHLPPRPSPTLPTLY---PVSSTHSSPSPDVAELWTGGTVAWESALEGGLGPV 97 EP G PP +P P L P + + P P V E ++ L P Sbjct: 156 EPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLE-----ALSPPHTLSSPSIPT 210 Query: 98 DSELWPTVGVASL--PPPPIAPLPEMKGNDSPLQPGTPTFPTPGPGLWDLQTVAVWGTFL 155 + P + PPPP P P SP GT FP G W VA+ G Sbjct: 211 PPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWK-SDVALNGRQA 269 Query: 156 PTTLTDLGHTP-EP---ALNPGPKGQ---PESLSPEVPLSSRLLSMP---AWDSPAN--- 202 T +P EP AL P P+ P S P R S+P A ++P Sbjct: 270 EATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEG 329 Query: 203 -SHRAPETQPLPPS 215 + +AP PLPPS Sbjct: 330 ATKKAPSRLPLPPS 343 Score = 39.7 bits (91), Expect = 0.002 Identities = 55/208 (26%), Positives = 75/208 (36%), Gaps = 43/208 (20%) Query: 32 GPMRFSNDEEPEGCGAPHLPPRPSPTLPTLYPVSSTHSS----PSPDVAELWTGGTVAWE 87 G RF+ E G PR P L T P+++ + P+P V + + V Sbjct: 54 GDNRFNTVSE-SGTATLKARPRVRPLL-TFLPLNAQENHGLAVPTPSVPDDFADKEVTGT 111 Query: 88 SALEGGLGPVDSELWPTVGVAS---------LPPPPIAPLPEMKGNDSPLQPGTPTFPTP 138 S+L G + L+ +VG +PPPP P P D PG P+P Sbjct: 112 SSLVNG----NLRLYSSVGDLRPGQYGQDLLIPPPPPGPAPGPP-QDISEPPGGSPLPSP 166 Query: 139 GPGLWDLQTVAVWGTFLPTTLTDLGHTPEPALNPGPKGQPESLSPEVPLSSRLLSMPAWD 198 T P L P P++ P P E+LSP LSS + P Sbjct: 167 P------------STAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTP--- 211 Query: 199 SPANSHRAPETQPLPPSLAEAGPPTDPL 226 P+ P P LA PP P+ Sbjct: 212 --------PDFIPPAPPLAFLAPPPPPV 231 Score = 35.8 bits (81), Expect = 0.032 Identities = 45/180 (25%), Positives = 65/180 (36%), Gaps = 23/180 (12%) Query: 22 RASCPLHGRTGPMRFSNDEEP-EGCGAPHLPPRPSPTLPTLYPVSSTHSSPSPDVAELWT 80 +A+ P R G + DE AP LPP P+P LP P + P P Sbjct: 367 KATAPASPRLGQSQSQADERAGTPPPAPPLPP-PAPPLPPPAPPLPPAAPPLP------- 418 Query: 81 GGTVAWESALEGGLGPVDSELWPTVGVASLPPPPIAPLPEMKGNDSPLQPGTPTFPTPGP 140 A + P P +L P P P PE + +P+ P+ Sbjct: 419 -------CAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEK-- 469 Query: 141 GLWDLQTVAVWGTFLPTTLTDLGHTPEPALNPGPKGQPESLSPEVPLSSRLLSMPAWDSP 200 L + + G+ L H P P + P+ + P +P LLS+PA D+P Sbjct: 470 -LRNELAAYLCGSRREDRF--LSHRPGPTV--APQSKEGKKGPRLPEKETLLSLPAKDTP 524 >gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo sapiens] Length = 1188 Score = 45.4 bits (106), Expect = 4e-05 Identities = 56/194 (28%), Positives = 71/194 (36%), Gaps = 25/194 (12%) Query: 41 EPEGCGAPHLPPRPSPTLPTLY---PVSSTHSSPSPDVAELWTGGTVAWESALEGGLGPV 97 EP G PP +P P L P + + P P V E ++ L P Sbjct: 156 EPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLE-----ALSPPHTLSSPSIPT 210 Query: 98 DSELWPTVGVASL--PPPPIAPLPEMKGNDSPLQPGTPTFPTPGPGLWDLQTVAVWGTFL 155 + P + PPPP P P SP GT FP G W VA+ G Sbjct: 211 PPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWK-SDVALNGRQA 269 Query: 156 PTTLTDLGHTP-EP---ALNPGPKGQ---PESLSPEVPLSSRLLSMP---AWDSPAN--- 202 T +P EP AL P P+ P S P R S+P A ++P Sbjct: 270 EATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEG 329 Query: 203 -SHRAPETQPLPPS 215 + +AP PLPPS Sbjct: 330 ATKKAPSRLPLPPS 343 Score = 39.7 bits (91), Expect = 0.002 Identities = 55/208 (26%), Positives = 75/208 (36%), Gaps = 43/208 (20%) Query: 32 GPMRFSNDEEPEGCGAPHLPPRPSPTLPTLYPVSSTHSS----PSPDVAELWTGGTVAWE 87 G RF+ E G PR P L T P+++ + P+P V + + V Sbjct: 54 GDNRFNTVSE-SGTATLKARPRVRPLL-TFLPLNAQENHGLAVPTPSVPDDFADKEVTGT 111 Query: 88 SALEGGLGPVDSELWPTVGVAS---------LPPPPIAPLPEMKGNDSPLQPGTPTFPTP 138 S+L G + L+ +VG +PPPP P P D PG P+P Sbjct: 112 SSLVNG----NLRLYSSVGDLRPGQYGQDLLIPPPPPGPAPGPP-QDISEPPGGSPLPSP 166 Query: 139 GPGLWDLQTVAVWGTFLPTTLTDLGHTPEPALNPGPKGQPESLSPEVPLSSRLLSMPAWD 198 T P L P P++ P P E+LSP LSS + P Sbjct: 167 P------------STAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTP--- 211 Query: 199 SPANSHRAPETQPLPPSLAEAGPPTDPL 226 P+ P P LA PP P+ Sbjct: 212 --------PDFIPPAPPLAFLAPPPPPV 231 Score = 35.8 bits (81), Expect = 0.032 Identities = 45/180 (25%), Positives = 65/180 (36%), Gaps = 23/180 (12%) Query: 22 RASCPLHGRTGPMRFSNDEEP-EGCGAPHLPPRPSPTLPTLYPVSSTHSSPSPDVAELWT 80 +A+ P R G + DE AP LPP P+P LP P + P P Sbjct: 367 KATAPASPRLGQSQSQADERAGTPPPAPPLPP-PAPPLPPPAPPLPPAAPPLP------- 418 Query: 81 GGTVAWESALEGGLGPVDSELWPTVGVASLPPPPIAPLPEMKGNDSPLQPGTPTFPTPGP 140 A + P P +L P P P PE + +P+ P+ Sbjct: 419 -------CAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEK-- 469 Query: 141 GLWDLQTVAVWGTFLPTTLTDLGHTPEPALNPGPKGQPESLSPEVPLSSRLLSMPAWDSP 200 L + + G+ L H P P + P+ + P +P LLS+PA D+P Sbjct: 470 -LRNELAAYLCGSRREDRF--LSHRPGPTV--APQSKEGKKGPRLPEKETLLSLPAKDTP 524 >gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sapiens] Length = 1188 Score = 45.4 bits (106), Expect = 4e-05 Identities = 56/194 (28%), Positives = 71/194 (36%), Gaps = 25/194 (12%) Query: 41 EPEGCGAPHLPPRPSPTLPTLY---PVSSTHSSPSPDVAELWTGGTVAWESALEGGLGPV 97 EP G PP +P P L P + + P P V E ++ L P Sbjct: 156 EPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLE-----ALSPPHTLSSPSIPT 210 Query: 98 DSELWPTVGVASL--PPPPIAPLPEMKGNDSPLQPGTPTFPTPGPGLWDLQTVAVWGTFL 155 + P + PPPP P P SP GT FP G W VA+ G Sbjct: 211 PPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWK-SDVALNGRQA 269 Query: 156 PTTLTDLGHTP-EP---ALNPGPKGQ---PESLSPEVPLSSRLLSMP---AWDSPAN--- 202 T +P EP AL P P+ P S P R S+P A ++P Sbjct: 270 EATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEG 329 Query: 203 -SHRAPETQPLPPS 215 + +AP PLPPS Sbjct: 330 ATKKAPSRLPLPPS 343 Score = 39.7 bits (91), Expect = 0.002 Identities = 55/208 (26%), Positives = 75/208 (36%), Gaps = 43/208 (20%) Query: 32 GPMRFSNDEEPEGCGAPHLPPRPSPTLPTLYPVSSTHSS----PSPDVAELWTGGTVAWE 87 G RF+ E G PR P L T P+++ + P+P V + + V Sbjct: 54 GDNRFNTVSE-SGTATLKARPRVRPLL-TFLPLNAQENHGLAVPTPSVPDDFADKEVTGT 111 Query: 88 SALEGGLGPVDSELWPTVGVAS---------LPPPPIAPLPEMKGNDSPLQPGTPTFPTP 138 S+L G + L+ +VG +PPPP P P D PG P+P Sbjct: 112 SSLVNG----NLRLYSSVGDLRPGQYGQDLLIPPPPPGPAPGPP-QDISEPPGGSPLPSP 166 Query: 139 GPGLWDLQTVAVWGTFLPTTLTDLGHTPEPALNPGPKGQPESLSPEVPLSSRLLSMPAWD 198 T P L P P++ P P E+LSP LSS + P Sbjct: 167 P------------STAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTP--- 211 Query: 199 SPANSHRAPETQPLPPSLAEAGPPTDPL 226 P+ P P LA PP P+ Sbjct: 212 --------PDFIPPAPPLAFLAPPPPPV 231 Score = 35.8 bits (81), Expect = 0.032 Identities = 45/180 (25%), Positives = 65/180 (36%), Gaps = 23/180 (12%) Query: 22 RASCPLHGRTGPMRFSNDEEP-EGCGAPHLPPRPSPTLPTLYPVSSTHSSPSPDVAELWT 80 +A+ P R G + DE AP LPP P+P LP P + P P Sbjct: 367 KATAPASPRLGQSQSQADERAGTPPPAPPLPP-PAPPLPPPAPPLPPAAPPLP------- 418 Query: 81 GGTVAWESALEGGLGPVDSELWPTVGVASLPPPPIAPLPEMKGNDSPLQPGTPTFPTPGP 140 A + P P +L P P P PE + +P+ P+ Sbjct: 419 -------CAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEK-- 469 Query: 141 GLWDLQTVAVWGTFLPTTLTDLGHTPEPALNPGPKGQPESLSPEVPLSSRLLSMPAWDSP 200 L + + G+ L H P P + P+ + P +P LLS+PA D+P Sbjct: 470 -LRNELAAYLCGSRREDRF--LSHRPGPTV--APQSKEGKKGPRLPEKETLLSLPAKDTP 524 >gi|153792074 proline rich 12 [Homo sapiens] Length = 2036 Score = 45.4 bits (106), Expect = 4e-05 Identities = 38/120 (31%), Positives = 47/120 (39%), Gaps = 6/120 (5%) Query: 107 VASLPPPPIAPLPEMKGNDSPLQPGTPTFPTPGPG-LWDLQTVAVWGTFLPTTLTDLGHT 165 +++L PP+A + D P P P PGP L L + GT P L + Sbjct: 1402 ISALDDPPLAGPKDTSTPDGP--PLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEE---K 1456 Query: 166 PEPALNPGPKGQPESLSPEVPLSSRLLSMPAWDSPANSHRAPETQPLPPSLAEAGPPTDP 225 P P P P QP+ P P L S P +P S P P PP A PP P Sbjct: 1457 PPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPP 1516 Score = 33.5 bits (75), Expect = 0.16 Identities = 49/185 (26%), Positives = 66/185 (35%), Gaps = 26/185 (14%) Query: 36 FSNDEEPEGCGAPHLPPRPSPTLPTLY--PVSSTHSSPSPDVAELWTGGTVAWESALEGG 93 FS+DEE L S + L P++ + +PD L V L G Sbjct: 1380 FSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPG- 1438 Query: 94 LGPVDSELWPTVGVASLPPPPI---APLPEMKGNDSPLQPGTPTFPTPGPGLWDLQTVAV 150 L +S P + PPP AP P+ + P P P P+P P Sbjct: 1439 LPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPP-PPPQPALPSPPP---------- 1487 Query: 151 WGTFLPTTLTDLGHTPEPALNPGPKGQPESLSPEVPLSSRLLSMPAWDSPANSHRAPE-- 208 PT + P P L P P S P P ++ L+ P + A S PE Sbjct: 1488 --LVAPTPSSP----PPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELP 1541 Query: 209 -TQPL 212 T+PL Sbjct: 1542 DTRPL 1546 Score = 31.6 bits (70), Expect = 0.60 Identities = 39/140 (27%), Positives = 47/140 (33%), Gaps = 19/140 (13%) Query: 42 PEGCGAPHLPP-RPSPTLPTLYPVSSTHSSPSPDVAELWTG-GTVAWESALEGGLGPVDS 99 P G G PP RP P P P L T +A SA Sbjct: 216 PAGLGPAQTPPYRPGPP------------DPPPPPRHLPTQFNLLASSSAAAAAAEQSSP 263 Query: 100 ELWPTVGVASLPPPPIAPLPEMKGNDSPLQ-PGTPTFPTPGPGLWDLQTVAVWGTFLPTT 158 +L+ G A PPPP LP Q P + P P P LQ G P+ Sbjct: 264 QLYNFSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPS- 322 Query: 159 LTDLGHTPEPALNPGPKGQP 178 +GH A +P G+P Sbjct: 323 ---MGHRANLACSPLGGGEP 339 >gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] Length = 1263 Score = 44.7 bits (104), Expect = 7e-05 Identities = 53/174 (30%), Positives = 62/174 (35%), Gaps = 19/174 (10%) Query: 50 LPPRPSPTLPTLYPVSSTHSSPSPDVAELWTGGTVAWESALEGGLGPVDSELWPTVGVAS 109 +PP P+P T P P P + G ++ +L GG S P G A+ Sbjct: 587 IPPPPAPGDSTTPPPPPPPPPPPPPLPG---GVCISSPPSLPGGTAI--SPPPPLSGDAT 641 Query: 110 LPPPPIAPLPEMKGNDSPLQ-PGTPTFPTPGPGLWDLQTVAVWGTFLPTTLTDLGHTPEP 168 +PPPP PLPE G SP PG P P P L A P G P P Sbjct: 642 IPPPP--PLPEGVGIPSPSSLPGGTAIPPPPP----LPGSARIPPPPPPLPGSAGIPPPP 695 Query: 169 ALNPGPKGQPESLSPEVPLSSRLLSMPAWDSPANSHRAPETQPLPPSLAEAGPP 222 PG G P P PL P P P P PP + PP Sbjct: 696 PPLPGEAGMP---PPPPPLPGG----PGIPPPPPFPGGPGIPPPPPGMGMPPPP 742 Score = 33.9 bits (76), Expect = 0.12 Identities = 34/118 (28%), Positives = 44/118 (37%), Gaps = 6/118 (5%) Query: 111 PPPPIAPLPEMKGN--DSPLQPGTPTFPTPGPGLWDLQTVAVWGTFLPTTLTDLGHTPEP 168 P PP PLP G P PG T P P P G + + + G T Sbjct: 572 PVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGT--- 628 Query: 169 ALNPGPKGQPESLSPEVPLSSRLLSMPAWDSPANSHRAPETQPLPPSLAEAGPPTDPL 226 A++P P ++ P P + +P+ S P PLP S A PP PL Sbjct: 629 AISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGS-ARIPPPPPPL 685 >gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] Length = 1272 Score = 44.7 bits (104), Expect = 7e-05 Identities = 53/174 (30%), Positives = 62/174 (35%), Gaps = 19/174 (10%) Query: 50 LPPRPSPTLPTLYPVSSTHSSPSPDVAELWTGGTVAWESALEGGLGPVDSELWPTVGVAS 109 +PP P+P T P P P + G ++ +L GG S P G A+ Sbjct: 596 IPPPPAPGDSTTPPPPPPPPPPPPPLPG---GVCISSPPSLPGGTAI--SPPPPLSGDAT 650 Query: 110 LPPPPIAPLPEMKGNDSPLQ-PGTPTFPTPGPGLWDLQTVAVWGTFLPTTLTDLGHTPEP 168 +PPPP PLPE G SP PG P P P L A P G P P Sbjct: 651 IPPPP--PLPEGVGIPSPSSLPGGTAIPPPPP----LPGSARIPPPPPPLPGSAGIPPPP 704 Query: 169 ALNPGPKGQPESLSPEVPLSSRLLSMPAWDSPANSHRAPETQPLPPSLAEAGPP 222 PG G P P PL P P P P PP + PP Sbjct: 705 PPLPGEAGMP---PPPPPLPGG----PGIPPPPPFPGGPGIPPPPPGMGMPPPP 751 Score = 33.9 bits (76), Expect = 0.12 Identities = 34/118 (28%), Positives = 44/118 (37%), Gaps = 6/118 (5%) Query: 111 PPPPIAPLPEMKGN--DSPLQPGTPTFPTPGPGLWDLQTVAVWGTFLPTTLTDLGHTPEP 168 P PP PLP G P PG T P P P G + + + G T Sbjct: 581 PVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGT--- 637 Query: 169 ALNPGPKGQPESLSPEVPLSSRLLSMPAWDSPANSHRAPETQPLPPSLAEAGPPTDPL 226 A++P P ++ P P + +P+ S P PLP S A PP PL Sbjct: 638 AISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGS-ARIPPPPPPL 694 >gi|18079216 CASK interacting protein 1 [Homo sapiens] Length = 1431 Score = 44.3 bits (103), Expect = 9e-05 Identities = 62/209 (29%), Positives = 71/209 (33%), Gaps = 30/209 (14%) Query: 28 HGRTGPMRFSNDEEPEGCGAPHLPPRPSPTLPTLYPVSSTHSSPSP---DVAELWTGGTV 84 H TG +R E G P LPP P P P P H P P A V Sbjct: 1171 HNGTGTVR--RRPASEQAGPPELPPPPPPAEPP--PTDLAHLPPLPPPEGEARKPAKPPV 1226 Query: 85 AWESALEGGLGPVDSELWPTVGVASLPPPPIAPLPEMKGNDSPLQPGTPTFPT-PGPGLW 143 + + L + + PT LP P + G P+ P P PT P P Sbjct: 1227 SPKPVLTQPVPKLQGSPTPTSKKVPLPGPGSPEVKRAHGTPPPVSPKPPPPPTAPKP--- 1283 Query: 144 DLQTVAVWGTFLPTTLTDLGHTPEPALNP-----GPKGQPESL--SPEVPLSSRLLSMPA 196 AV G LP+ P PA P P G P SL SP P S PA Sbjct: 1284 ---VKAVAG--LPSGSAGPSPAPSPARQPPAALAKPPGTPPSLGASPAKPPSP---GAPA 1335 Query: 197 WDSPANSHRAPETQPLPPSLAEAGPPTDP 225 PA RA + A A PP P Sbjct: 1336 LHVPAKPPRAAAA----AAAAAAAPPAPP 1360 >gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] Length = 1012 Score = 43.5 bits (101), Expect = 2e-04 Identities = 52/189 (27%), Positives = 66/189 (34%), Gaps = 17/189 (8%) Query: 46 GAPHLP-PRPSPTLPTLYPVSSTHSSPSPDVAELWTGGTVAWESALEGGLGPVDSELWPT 104 G P LP P P+P+ + P S +S +P+ + T L P P Sbjct: 203 GTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPS-PH 261 Query: 105 VGVASLPPPPIAPLPEMKGNDSPLQPGTPTFPTPGP-GLWDLQTVAVWGTFL--PTTLTD 161 P PP+ PL G S P GP G LQ G L P Sbjct: 262 PPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQA----GPLLQHPGPPQP 317 Query: 162 LGHTPEPALNPGPKGQPESLSPEVPLSSRLLSMPAWDSPANSHRAPETQPLPPSLAE--- 218 G P+ + P G SP L +PA S S + P QPLPP+ Sbjct: 318 FGLPPQASQGQAPLGT----SPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPH 373 Query: 219 -AGPPTDPL 226 PPT P+ Sbjct: 374 IKPPPTTPI 382 Score = 42.0 bits (97), Expect = 4e-04 Identities = 66/228 (28%), Positives = 87/228 (38%), Gaps = 39/228 (17%) Query: 7 PPLRAKMIS--QLARTARASCPLHGRTGPMRFSNDEEPEGCGAPHLPPRPSPTLPT-LYP 63 PPL+ S Q + + A PLHG+ P P A L P P P L P Sbjct: 270 PPLQPLTGSAGQPSAPSHAQPPLHGQGPP-------GPHSLQAGPLLQHPGPPQPFGLPP 322 Query: 64 VSSTHSSP---SPDVAELWTGGTV-AWESALEGGLGPVDSELWPT-VGVASLPPPPIAPL 118 +S +P SP A T + A +SAL+ P + L P + + + PPP P+ Sbjct: 323 QASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPI 382 Query: 119 PEMKGNDSPLQPGTPTFPTPGPGLWDLQTVAVWGTFLPTTLTDLGHTPEPALNPGPK--- 175 P++ + P P P P + LP P PAL P Sbjct: 383 PQLPAPQAHKHP--PHLSGPSPFSMNAN--------LP---------PPPALKPLSSLST 423 Query: 176 GQPESLSPEVPLSSRLLSMPAWDSPANSHRAPETQPLPPSLAEAGPPT 223 P S P PL S P SPA ++Q LPP A + PPT Sbjct: 424 HHPPSAHPP-PLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPA-SHPPT 469 Score = 37.4 bits (85), Expect = 0.011 Identities = 60/201 (29%), Positives = 76/201 (37%), Gaps = 23/201 (11%) Query: 42 PEGCGAPHLPPRPSPTLPTLYPVSSTHSSPS-PDVAE--LWTGGTVAWESALEGGL---- 94 P+ +PH PP PSP P L P++ + PS P A+ L G S G L Sbjct: 254 PQRPPSPHPPPHPSPH-PPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHP 312 Query: 95 GPVDSELWP---TVGVASLPPPPIAPLP----EMKGNDSPLQPGTP--TFPTPGPGLWDL 145 GP P + G A L P A P ++ + S LQ P P P L Sbjct: 313 GPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMP 372 Query: 146 QTVAVWGTFLPTTLTDLGHTPEPALN-PGPKGQPESLSPE---VPLSSRLLSMPAWDSPA 201 T +P H P L+ P P +L P PLSS P P Sbjct: 373 HIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPP 432 Query: 202 NSHRAPETQPLPPSLAEAGPP 222 P++QPLP S A+ PP Sbjct: 433 PLQLMPQSQPLPSSPAQ--PP 451 Score = 33.1 bits (74), Expect = 0.21 Identities = 32/119 (26%), Positives = 43/119 (36%), Gaps = 28/119 (23%) Query: 112 PPPIAPLPEMKGNDSPLQPGTPTFPTPGPGLWDLQTVAVWGTFLPTTLTDLGHTPEPALN 171 P + P P S PGTP PTPGP + T + P + Sbjct: 190 PTGVTPAP------SSAPPGTPQLPTPGP---------------TPSATAVPPQGSPTAS 228 Query: 172 PGPKGQPESLSPEVPLSSRLLSMPAW--DSPANSHRAPETQPLP---PSLAEAGPPTDP 225 P QP++ + VP + + PA P + H P P P P AG P+ P Sbjct: 229 QAP-NQPQAPTAPVP-HTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAP 285 Score = 31.6 bits (70), Expect = 0.60 Identities = 28/98 (28%), Positives = 38/98 (38%), Gaps = 15/98 (15%) Query: 41 EPEGCGAPHLPPRPSPTLPTLYPVSSTHSSPSPDVAELWTGGTVAWESALEGGLGPVDSE 100 +P P +P P P P P +ST + A+ G A ++ GG S Sbjct: 477 QPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGG----SSC 532 Query: 101 LWPTVGVA-----------SLPPPPIAPLPEMKGNDSP 127 PTV + S PPPP +P PE D+P Sbjct: 533 PLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTP 570 Score = 28.5 bits (62), Expect = 5.1 Identities = 32/100 (32%), Positives = 41/100 (41%), Gaps = 14/100 (14%) Query: 56 PTLPTLYPVSS--THSSPS---PDVAELWTGGTVAWESALEGGLG-----PVDSELWPTV 105 P P L P+SS TH PS P + + + A GL P P Sbjct: 410 PPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPT 469 Query: 106 GVASLPP-PPIAPLPEMKGNDSPLQPGT-PTFPTP--GPG 141 G+ + P PP A P + G P+ P T P+ TP GPG Sbjct: 470 GLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPG 509 >gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 43.5 bits (101), Expect = 2e-04 Identities = 52/189 (27%), Positives = 66/189 (34%), Gaps = 17/189 (8%) Query: 46 GAPHLP-PRPSPTLPTLYPVSSTHSSPSPDVAELWTGGTVAWESALEGGLGPVDSELWPT 104 G P LP P P+P+ + P S +S +P+ + T L P P Sbjct: 757 GTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPS-PH 815 Query: 105 VGVASLPPPPIAPLPEMKGNDSPLQPGTPTFPTPGP-GLWDLQTVAVWGTFL--PTTLTD 161 P PP+ PL G S P GP G LQ G L P Sbjct: 816 PPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQA----GPLLQHPGPPQP 871 Query: 162 LGHTPEPALNPGPKGQPESLSPEVPLSSRLLSMPAWDSPANSHRAPETQPLPPSLAE--- 218 G P+ + P G SP L +PA S S + P QPLPP+ Sbjct: 872 FGLPPQASQGQAPLGT----SPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPH 927 Query: 219 -AGPPTDPL 226 PPT P+ Sbjct: 928 IKPPPTTPI 936 Score = 42.0 bits (97), Expect = 4e-04 Identities = 66/228 (28%), Positives = 87/228 (38%), Gaps = 39/228 (17%) Query: 7 PPLRAKMIS--QLARTARASCPLHGRTGPMRFSNDEEPEGCGAPHLPPRPSPTLPT-LYP 63 PPL+ S Q + + A PLHG+ P P A L P P P L P Sbjct: 824 PPLQPLTGSAGQPSAPSHAQPPLHGQGPP-------GPHSLQAGPLLQHPGPPQPFGLPP 876 Query: 64 VSSTHSSP---SPDVAELWTGGTV-AWESALEGGLGPVDSELWPT-VGVASLPPPPIAPL 118 +S +P SP A T + A +SAL+ P + L P + + + PPP P+ Sbjct: 877 QASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPI 936 Query: 119 PEMKGNDSPLQPGTPTFPTPGPGLWDLQTVAVWGTFLPTTLTDLGHTPEPALNPGPK--- 175 P++ + P P P P + LP P PAL P Sbjct: 937 PQLPAPQAHKHP--PHLSGPSPFSMNAN--------LP---------PPPALKPLSSLST 977 Query: 176 GQPESLSPEVPLSSRLLSMPAWDSPANSHRAPETQPLPPSLAEAGPPT 223 P S P PL S P SPA ++Q LPP A + PPT Sbjct: 978 HHPPSAHPP-PLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPA-SHPPT 1023 Score = 37.4 bits (85), Expect = 0.011 Identities = 60/201 (29%), Positives = 76/201 (37%), Gaps = 23/201 (11%) Query: 42 PEGCGAPHLPPRPSPTLPTLYPVSSTHSSPS-PDVAE--LWTGGTVAWESALEGGL---- 94 P+ +PH PP PSP P L P++ + PS P A+ L G S G L Sbjct: 808 PQRPPSPHPPPHPSPH-PPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHP 866 Query: 95 GPVDSELWP---TVGVASLPPPPIAPLP----EMKGNDSPLQPGTP--TFPTPGPGLWDL 145 GP P + G A L P A P ++ + S LQ P P P L Sbjct: 867 GPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMP 926 Query: 146 QTVAVWGTFLPTTLTDLGHTPEPALN-PGPKGQPESLSPE---VPLSSRLLSMPAWDSPA 201 T +P H P L+ P P +L P PLSS P P Sbjct: 927 HIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPP 986 Query: 202 NSHRAPETQPLPPSLAEAGPP 222 P++QPLP S A+ PP Sbjct: 987 PLQLMPQSQPLPSSPAQ--PP 1005 Score = 33.1 bits (74), Expect = 0.21 Identities = 32/119 (26%), Positives = 43/119 (36%), Gaps = 28/119 (23%) Query: 112 PPPIAPLPEMKGNDSPLQPGTPTFPTPGPGLWDLQTVAVWGTFLPTTLTDLGHTPEPALN 171 P + P P S PGTP PTPGP + T + P + Sbjct: 744 PTGVTPAP------SSAPPGTPQLPTPGP---------------TPSATAVPPQGSPTAS 782 Query: 172 PGPKGQPESLSPEVPLSSRLLSMPAW--DSPANSHRAPETQPLP---PSLAEAGPPTDP 225 P QP++ + VP + + PA P + H P P P P AG P+ P Sbjct: 783 QAP-NQPQAPTAPVP-HTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAP 839 Score = 31.6 bits (70), Expect = 0.60 Identities = 28/98 (28%), Positives = 38/98 (38%), Gaps = 15/98 (15%) Query: 41 EPEGCGAPHLPPRPSPTLPTLYPVSSTHSSPSPDVAELWTGGTVAWESALEGGLGPVDSE 100 +P P +P P P P P +ST + A+ G A ++ GG S Sbjct: 1031 QPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGG----SSC 1086 Query: 101 LWPTVGVA-----------SLPPPPIAPLPEMKGNDSP 127 PTV + S PPPP +P PE D+P Sbjct: 1087 PLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTP 1124 Score = 28.5 bits (62), Expect = 5.1 Identities = 32/100 (32%), Positives = 41/100 (41%), Gaps = 14/100 (14%) Query: 56 PTLPTLYPVSS--THSSPS---PDVAELWTGGTVAWESALEGGLG-----PVDSELWPTV 105 P P L P+SS TH PS P + + + A GL P P Sbjct: 964 PPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPT 1023 Query: 106 GVASLPP-PPIAPLPEMKGNDSPLQPGT-PTFPTP--GPG 141 G+ + P PP A P + G P+ P T P+ TP GPG Sbjct: 1024 GLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPG 1063 >gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 43.5 bits (101), Expect = 2e-04 Identities = 52/189 (27%), Positives = 66/189 (34%), Gaps = 17/189 (8%) Query: 46 GAPHLP-PRPSPTLPTLYPVSSTHSSPSPDVAELWTGGTVAWESALEGGLGPVDSELWPT 104 G P LP P P+P+ + P S +S +P+ + T L P P Sbjct: 757 GTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPS-PH 815 Query: 105 VGVASLPPPPIAPLPEMKGNDSPLQPGTPTFPTPGP-GLWDLQTVAVWGTFL--PTTLTD 161 P PP+ PL G S P GP G LQ G L P Sbjct: 816 PPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQA----GPLLQHPGPPQP 871 Query: 162 LGHTPEPALNPGPKGQPESLSPEVPLSSRLLSMPAWDSPANSHRAPETQPLPPSLAE--- 218 G P+ + P G SP L +PA S S + P QPLPP+ Sbjct: 872 FGLPPQASQGQAPLGT----SPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPH 927 Query: 219 -AGPPTDPL 226 PPT P+ Sbjct: 928 IKPPPTTPI 936 Score = 42.0 bits (97), Expect = 4e-04 Identities = 66/228 (28%), Positives = 87/228 (38%), Gaps = 39/228 (17%) Query: 7 PPLRAKMIS--QLARTARASCPLHGRTGPMRFSNDEEPEGCGAPHLPPRPSPTLPT-LYP 63 PPL+ S Q + + A PLHG+ P P A L P P P L P Sbjct: 824 PPLQPLTGSAGQPSAPSHAQPPLHGQGPP-------GPHSLQAGPLLQHPGPPQPFGLPP 876 Query: 64 VSSTHSSP---SPDVAELWTGGTV-AWESALEGGLGPVDSELWPT-VGVASLPPPPIAPL 118 +S +P SP A T + A +SAL+ P + L P + + + PPP P+ Sbjct: 877 QASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPI 936 Query: 119 PEMKGNDSPLQPGTPTFPTPGPGLWDLQTVAVWGTFLPTTLTDLGHTPEPALNPGPK--- 175 P++ + P P P P + LP P PAL P Sbjct: 937 PQLPAPQAHKHP--PHLSGPSPFSMNAN--------LP---------PPPALKPLSSLST 977 Query: 176 GQPESLSPEVPLSSRLLSMPAWDSPANSHRAPETQPLPPSLAEAGPPT 223 P S P PL S P SPA ++Q LPP A + PPT Sbjct: 978 HHPPSAHPP-PLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPA-SHPPT 1023 Score = 37.4 bits (85), Expect = 0.011 Identities = 60/201 (29%), Positives = 76/201 (37%), Gaps = 23/201 (11%) Query: 42 PEGCGAPHLPPRPSPTLPTLYPVSSTHSSPS-PDVAE--LWTGGTVAWESALEGGL---- 94 P+ +PH PP PSP P L P++ + PS P A+ L G S G L Sbjct: 808 PQRPPSPHPPPHPSPH-PPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHP 866 Query: 95 GPVDSELWP---TVGVASLPPPPIAPLP----EMKGNDSPLQPGTP--TFPTPGPGLWDL 145 GP P + G A L P A P ++ + S LQ P P P L Sbjct: 867 GPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMP 926 Query: 146 QTVAVWGTFLPTTLTDLGHTPEPALN-PGPKGQPESLSPE---VPLSSRLLSMPAWDSPA 201 T +P H P L+ P P +L P PLSS P P Sbjct: 927 HIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPP 986 Query: 202 NSHRAPETQPLPPSLAEAGPP 222 P++QPLP S A+ PP Sbjct: 987 PLQLMPQSQPLPSSPAQ--PP 1005 Score = 33.1 bits (74), Expect = 0.21 Identities = 32/119 (26%), Positives = 43/119 (36%), Gaps = 28/119 (23%) Query: 112 PPPIAPLPEMKGNDSPLQPGTPTFPTPGPGLWDLQTVAVWGTFLPTTLTDLGHTPEPALN 171 P + P P S PGTP PTPGP + T + P + Sbjct: 744 PTGVTPAP------SSAPPGTPQLPTPGP---------------TPSATAVPPQGSPTAS 782 Query: 172 PGPKGQPESLSPEVPLSSRLLSMPAW--DSPANSHRAPETQPLP---PSLAEAGPPTDP 225 P QP++ + VP + + PA P + H P P P P AG P+ P Sbjct: 783 QAP-NQPQAPTAPVP-HTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAP 839 Score = 31.6 bits (70), Expect = 0.60 Identities = 28/98 (28%), Positives = 38/98 (38%), Gaps = 15/98 (15%) Query: 41 EPEGCGAPHLPPRPSPTLPTLYPVSSTHSSPSPDVAELWTGGTVAWESALEGGLGPVDSE 100 +P P +P P P P P +ST + A+ G A ++ GG S Sbjct: 1031 QPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGG----SSC 1086 Query: 101 LWPTVGVA-----------SLPPPPIAPLPEMKGNDSP 127 PTV + S PPPP +P PE D+P Sbjct: 1087 PLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTP 1124 Score = 28.5 bits (62), Expect = 5.1 Identities = 32/100 (32%), Positives = 41/100 (41%), Gaps = 14/100 (14%) Query: 56 PTLPTLYPVSS--THSSPS---PDVAELWTGGTVAWESALEGGLG-----PVDSELWPTV 105 P P L P+SS TH PS P + + + A GL P P Sbjct: 964 PPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPT 1023 Query: 106 GVASLPP-PPIAPLPEMKGNDSPLQPGT-PTFPTP--GPG 141 G+ + P PP A P + G P+ P T P+ TP GPG Sbjct: 1024 GLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPG 1063 >gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo sapiens] Length = 5537 Score = 43.1 bits (100), Expect = 2e-04 Identities = 52/178 (29%), Positives = 67/178 (37%), Gaps = 37/178 (20%) Query: 51 PPRPSPTLPTLYPVSSTHSSPSPDVAELWTGGTVAWESALEGGLGPVDSELWPTVGVASL 110 PP SP P P + SP P+ + L+ +S L P + L Sbjct: 575 PPEESPMSP---PPEESPMSPPPEASRLFPPFE--------------ESPLSPPPEESPL 617 Query: 111 PPPPIAPLPEMKGNDSPLQPGTPTFP-TPGPGLWDLQTVAVWGTFLPTTLTDLGHTPEPA 169 PPP A DSP+ P P +P P + L + V P E Sbjct: 618 SPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPP-------PEESP 670 Query: 170 LNPGPKGQPESLSPEVPLSSRLLSMPAWDSPANSHRAPETQPLPPSLAEAGPPTDPLV 227 L+P P+ P S PE +SR LS P DSP + PE P P PP D L+ Sbjct: 671 LSPPPEESPTSPPPE---ASR-LSPPPEDSPTSP--PPEDSPASP------PPEDSLM 716 Score = 43.1 bits (100), Expect = 2e-04 Identities = 34/100 (34%), Positives = 47/100 (47%), Gaps = 8/100 (8%) Query: 29 GRTGPMRFSNDEEPEGCGAPHL-PPRPSPTLPTLYPVSSTHSSPSPDVAELW-TGGTVAW 86 G PMRF+ P+ G P L PP P P LP + ++S H P P + + T TVA Sbjct: 2529 GTPSPMRFTF---PQAVGEPSLKPPVPQPGLPPPHGINS-HFGPGPTLGKPQSTNYTVAT 2584 Query: 87 ESALEGG--LGPVDSELWPTVGVASLPPPPIAPLPEMKGN 124 + G LGP + G++ L PP + P P G+ Sbjct: 2585 GNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGS 2624 Score = 42.7 bits (99), Expect = 3e-04 Identities = 47/157 (29%), Positives = 62/157 (39%), Gaps = 40/157 (25%) Query: 96 PVDSELWPTVGVASLPP------------PPIAPLPEMKGNDSPLQPG---------TPT 134 P + L+P G SL P PP++PLPE + PL P P Sbjct: 877 PEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPE----ELPLSPSGEPSLSPQLMPP 932 Query: 135 FPTPGPGLWDLQTVAVWGTFLPTTLTDLGHTPEPALNPGPKGQPESLSPEVPLSSRLLSM 194 P P P L + T A P L+ LG P G KG + PE PL++ +L Sbjct: 933 DPLPPP-LSPIITAAA-----PPALSPLGELEYPF---GAKGDSD---PESPLAAPILET 980 Query: 195 PAWDSPANSHRAPETQP---LPPSLAEAGPPTDPLVV 228 P P + PE P LPPS P P+++ Sbjct: 981 PISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILM 1017 Score = 38.1 bits (87), Expect = 0.006 Identities = 63/215 (29%), Positives = 74/215 (34%), Gaps = 37/215 (17%) Query: 40 EEPEGCG---APHLPPRPS-------PTLPTLYP-VSSTHSSPSPDVAELWTGGTVAWES 88 EEP+ C PHL PRP P P L P H SP P+ L S Sbjct: 730 EEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLS 789 Query: 89 ALEGG--LGPVDSELW--PTVGVASLPPPPIAPLPEMKGNDSPLQPGTPTFPTPGPGLWD 144 G L P EL P L P P P + +S L P + P P + Sbjct: 790 PQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEE-PCLSPRPEE 848 Query: 145 LQTVAVWGTFLPTTLTDLGHTPEPALNPGPKGQ---PESLS----PEVPLSSRLLSMPAW 197 + L L +P P P GQ PE L P P S LL PA Sbjct: 849 --------SHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPAL 900 Query: 198 DSPANSHRAPETQPLP------PSLAEAGPPTDPL 226 P +P + LP PSL+ P DPL Sbjct: 901 SEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPL 935 Score = 35.8 bits (81), Expect = 0.032 Identities = 42/147 (28%), Positives = 55/147 (37%), Gaps = 18/147 (12%) Query: 94 LGPVDSELWPTVGVASLPPPPIAPLPEMKGNDSPLQPG---TPTFPTPGPGLWDLQTVAV 150 LG +L P + P+ P PE +SPL P +PT P P + Sbjct: 419 LGKAGVQLEPQLEAPLNEEMPLLPPPE----ESPLSPPPEESPTSPPPEASRLSPPPEEL 474 Query: 151 WGTFLPTTLTDLGHTPEPALNPGPKGQPES----LSPEVPLSSRLLSMPAWDSPANSHRA 206 + LP L E L+P P+ P S SP PL LS P P+ + Sbjct: 475 PASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALET 534 Query: 207 -----PETQPLPPSLAEA--GPPTDPL 226 PE PL P E+ PP + L Sbjct: 535 PLSPPPEASPLSPPFEESPLSPPPEEL 561 Score = 35.4 bits (80), Expect = 0.042 Identities = 54/179 (30%), Positives = 74/179 (41%), Gaps = 26/179 (14%) Query: 51 PPRPSPTLPTLYPVSSTHSSPSPDVAELWTGGTVAWESALEGGLG---PVD-SELWPTVG 106 PP SP P P + +SP P+ + L S L L P++ S L P Sbjct: 443 PPEESPLSP---PPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPE 499 Query: 107 VASLPPPPIAPLPEMKGNDSPLQPGTPTFPTPGPGLWDLQTVAVWGTFLPTTLTDLGHT- 165 + L PPP + P +SPL P + P+P L+T P + L Sbjct: 500 ESPLSPPPESS-PFSPLEESPLSPPEESPPSPA-----LETPLS----PPPEASPLSPPF 549 Query: 166 PEPALNPGPKGQPESLSPEVPLSSRLLSMPAWDSPANSHRAPETQPL--PPSLAEAGPP 222 E L+P P+ P S PE +SRL S P +SP + PE P+ PP + PP Sbjct: 550 EESPLSPPPEELPTSPPPE---ASRL-SPPPEESPMSP--PPEESPMSPPPEASRLFPP 602 Score = 32.7 bits (73), Expect = 0.27 Identities = 38/156 (24%), Positives = 54/156 (34%), Gaps = 48/156 (30%) Query: 51 PPRPSPTLPTLYPVSSTHSSPSPDVAELWTGGTVAWESALEGGLGPVDSELWPTVGVASL 110 PP SP P P ++ SP P+ + + P +S + P V+ L Sbjct: 611 PPEESPLSP---PPEASRLSPPPEDSPM--------------SPPPEESPMSPPPEVSRL 653 Query: 111 PPPPIAPLPEMKGNDSPLQPGTPTFPTPGPGLWDLQTVAVWGTFLPTTLTDLGHTPEPA- 169 P P+ +SPL P PT P PE + Sbjct: 654 SPLPVVSRLSPPPEESPLSPPPEESPTSPP-------------------------PEASR 688 Query: 170 LNPGPKGQPESLSPE-----VPLSSRLLSMPAWDSP 200 L+P P+ P S PE P L+S+P +SP Sbjct: 689 LSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESP 724 Score = 29.6 bits (65), Expect = 2.3 Identities = 35/152 (23%), Positives = 52/152 (34%), Gaps = 31/152 (20%) Query: 46 GAPHLPPR---PSPTLPTLYPVSSTHSSPSPDVAELWTGGTVAWESALEGGLGPVDSELW 102 G P L P+ P P P L P+ + + P+ L G + + +G P Sbjct: 921 GEPSLSPQLMPPDPLPPPLSPIITAAAPPA-----LSPLGELEYPFGAKGDSDPESPLAA 975 Query: 103 PTVGVASLPPP--------PIAPLPEMKGNDSPLQPGTPTFPTPGPGLWDLQTVAVWGTF 154 P + PPP P+ P+ SP+ P +P P P Sbjct: 976 PILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLP-------------- 1021 Query: 155 LPTTLTDLGHTPEPALNPGPKGQPESLSPEVP 186 P L H+ P +P + P +L VP Sbjct: 1022 -PQCSPLLQHSLVPQNSPPSQCSPPALPLSVP 1052 Score = 29.3 bits (64), Expect = 3.0 Identities = 32/118 (27%), Positives = 45/118 (38%), Gaps = 5/118 (4%) Query: 111 PPPPIAPLPEMKGNDSPLQPGTPTFPTPGPGLWDLQTVAVWGTFLPTTLTDLGHTPEPAL 170 PPP A P + +PG+ T P P L + L P + Sbjct: 2352 PPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRV 2411 Query: 171 NPGPKGQPESLSPEVPLSSRLLSMPAW-DSPANSH-RAPETQPLPPSLAEAGPPTDPL 226 P+ Q S S PL+ R LS A+ SP ++P+ PPS ++ P PL Sbjct: 2412 PASPQSQSSSQS---PLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPL 2466 Score = 29.3 bits (64), Expect = 3.0 Identities = 32/93 (34%), Positives = 38/93 (40%), Gaps = 9/93 (9%) Query: 136 PTPGPGLWDLQTVAVW-GTFLPTTLTDLGHTPEPALNPGPKGQPESLSPEVPLSSRLLSM 194 P GP W Q AV G L + L L + + P P Q L R LS Sbjct: 4850 PDTGPD-WLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSA 4908 Query: 195 PAWDSPANSHRAPETQPLPPSLAEAGPPTDPLV 227 P + P+ P PL PS A PPT+PLV Sbjct: 4909 PPPEEPS-----PPPSPLAPS--PASPPTEPLV 4934 Score = 28.5 bits (62), Expect = 5.1 Identities = 47/174 (27%), Positives = 61/174 (35%), Gaps = 45/174 (25%) Query: 49 HLPPRPSPTLPTLYPVSSTHSSPSPDVAELWTGGTVAWESALEGGLGPVDSELWPTVGVA 108 H PPRP P P+VA + G++A S GG A Sbjct: 2467 HKPPRPQP----------------PEVA--FKAGSLAHTSLGAGGF------------PA 2496 Query: 109 SLPPPPIAPLPEMKGNDSPLQPGTPTF-PTPGPGLWDLQTVAVWGTFLPTTLTDLGHTPE 167 +LP P L + P P F +PG G A GT P T E Sbjct: 2497 ALPAGPAGELHAKVPSGQP-----PNFVRSPGTG-------AFVGTPSPMRFTFPQAVGE 2544 Query: 168 PALNPGPKGQPESLSPEVPLSSRLLSMPAWDSPANSHRAPETQPLPPSLAEAGP 221 P+L P P QP L P ++S P P +++ T PS + GP Sbjct: 2545 PSLKP-PVPQP-GLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGP 2596 >gi|56118221 amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein [Homo sapiens] Length = 666 Score = 43.1 bits (100), Expect = 2e-04 Identities = 42/153 (27%), Positives = 54/153 (35%), Gaps = 25/153 (16%) Query: 38 NDEEPEGCGAPHLPPRPSPTLPTLYPVSSTHSSPSPDVAELWTGGTVAWESALEGGLGPV 97 N +P APH P P P + S T SP+ + TGG GGL Sbjct: 499 NHHDPAVPRAPHAPKSSLPPPPPVRRSSDTSGSPATPLKAKGTGG---------GGLPAP 549 Query: 98 DSELWPTVGVASLPPPPIAPLPEMKGNDSPLQPGTPTFPTPGPGLWDLQTVAVWGTFLPT 157 + P PPPP PL +D L P P F P P + G Sbjct: 550 PDDFLP-------PPPPPPPL-----DDPELPPPPPDFMEPPPDFVPPPPPSYAG----I 593 Query: 158 TLTDLGHTPEPALNPGPKGQPESLSPEVPLSSR 190 ++L P P P P P+S P ++ R Sbjct: 594 AGSELPPPPPPPPAPAPAPVPDSARPPPAVAKR 626 >gi|14602439 Williams Beuren syndrome chromosome region 14 isoform delta [Homo sapiens] Length = 831 Score = 42.7 bits (99), Expect = 3e-04 Identities = 40/125 (32%), Positives = 48/125 (38%), Gaps = 18/125 (14%) Query: 106 GVASLPPPPIAPL--PEMKGNDSPLQPGTPTFPT--PGPGLWDLQTVAVWGTFLPTTLTD 161 G+ PPPP P+ P + PL FPT P PG+ L A F PT Sbjct: 406 GLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAA---FPPT---- 458 Query: 162 LGHTPEPALNPGPKGQPESLSP---EVPLSSRLLSMPAWDSPANSHRAPETQPLPPSLAE 218 P+ +P P P L P P SMP PA S R + P + A Sbjct: 459 ----PQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPAT 514 Query: 219 AGPPT 223 A PPT Sbjct: 515 ASPPT 519 >gi|14602437 Williams Beuren syndrome chromosome region 14 isoform gamma [Homo sapiens] Length = 850 Score = 42.7 bits (99), Expect = 3e-04 Identities = 40/125 (32%), Positives = 48/125 (38%), Gaps = 18/125 (14%) Query: 106 GVASLPPPPIAPL--PEMKGNDSPLQPGTPTFPT--PGPGLWDLQTVAVWGTFLPTTLTD 161 G+ PPPP P+ P + PL FPT P PG+ L A F PT Sbjct: 406 GLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAA---FPPT---- 458 Query: 162 LGHTPEPALNPGPKGQPESLSP---EVPLSSRLLSMPAWDSPANSHRAPETQPLPPSLAE 218 P+ +P P P L P P SMP PA S R + P + A Sbjct: 459 ----PQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPAT 514 Query: 219 AGPPT 223 A PPT Sbjct: 515 ASPPT 519 >gi|14602435 Williams Beuren syndrome chromosome region 14 isoform beta [Homo sapiens] Length = 833 Score = 42.7 bits (99), Expect = 3e-04 Identities = 40/125 (32%), Positives = 48/125 (38%), Gaps = 18/125 (14%) Query: 106 GVASLPPPPIAPL--PEMKGNDSPLQPGTPTFPT--PGPGLWDLQTVAVWGTFLPTTLTD 161 G+ PPPP P+ P + PL FPT P PG+ L A F PT Sbjct: 406 GLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAA---FPPT---- 458 Query: 162 LGHTPEPALNPGPKGQPESLSP---EVPLSSRLLSMPAWDSPANSHRAPETQPLPPSLAE 218 P+ +P P P L P P SMP PA S R + P + A Sbjct: 459 ----PQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPAT 514 Query: 219 AGPPT 223 A PPT Sbjct: 515 ASPPT 519 >gi|14602433 Williams Beuren syndrome chromosome region 14 isoform alpha [Homo sapiens] Length = 852 Score = 42.7 bits (99), Expect = 3e-04 Identities = 40/125 (32%), Positives = 48/125 (38%), Gaps = 18/125 (14%) Query: 106 GVASLPPPPIAPL--PEMKGNDSPLQPGTPTFPT--PGPGLWDLQTVAVWGTFLPTTLTD 161 G+ PPPP P+ P + PL FPT P PG+ L A F PT Sbjct: 406 GLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAA---FPPT---- 458 Query: 162 LGHTPEPALNPGPKGQPESLSP---EVPLSSRLLSMPAWDSPANSHRAPETQPLPPSLAE 218 P+ +P P P L P P SMP PA S R + P + A Sbjct: 459 ----PQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPAT 514 Query: 219 AGPPT 223 A PPT Sbjct: 515 ASPPT 519 >gi|55750053 atrophin-1 [Homo sapiens] Length = 1190 Score = 42.0 bits (97), Expect = 4e-04 Identities = 52/183 (28%), Positives = 70/183 (38%), Gaps = 21/183 (11%) Query: 42 PEGCGAPHLPPRPSPTLPTLYPVSSTHSSPSPDVAELWTGGTVAWESALEGGLGPVDSEL 101 P P P P P +PT+ S+T S+ VA G +++A G P Sbjct: 588 PSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAG----YKTASPPGPPPYGKRA 643 Query: 102 WPTVGVASLPPPPIAPLPEMKGNDSPLQPGTPTFPTPGPGLWDLQTVAVWGTFLPTTLTD 161 + PP P G+ + GTP PG A GTF P + T Sbjct: 644 PSPGAYKTATPPGYKP-----GSPPSFRTGTP------PGYRGTSPPAGPGTFKPGSPT- 691 Query: 162 LGHTPEPALNPGPKGQPE-SLSPEVPLSSRLLS-MPAWDSPANSHRAPETQPLPPSLAEA 219 +G P P GP G P P P S LS PA + PE+ P+PP+ + + Sbjct: 692 VG--PGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPES-PVPPARSPS 748 Query: 220 GPP 222 PP Sbjct: 749 PPP 751 Score = 37.0 bits (84), Expect = 0.014 Identities = 66/249 (26%), Positives = 81/249 (32%), Gaps = 40/249 (16%) Query: 19 RTARASCPLHGRTGPMRFSNDEEPEGCGAPHLPPRPSPTLPTLYPVSSTHSSPSPDVAEL 78 R AS H P + EP PP P P LYP + P + Sbjct: 177 RQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPK 236 Query: 79 WTGGTVAWESALEGGL--GPVDSELWPTVGVASLPPPPIAPLPEMKGNDSPLQPGTPTFP 136 GG + GG P + + + AS PP P + G + P P FP Sbjct: 237 -GGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFP 295 Query: 137 ------TPGPGLWDLQTVAVWGTFLPTTLTDLGHTPEP--------ALNPGP-KG----- 176 P P L L + L GH P P L PGP KG Sbjct: 296 HVTPNLPPPPALRPLNNASASPPGLGAQPLP-GHLPSPHAMGQGMGGLPPGPEKGPTLAP 354 Query: 177 QPESLSP----------EVPLSSRLLSMPAWDSPANSHRA-----PETQPLPPSLAEAGP 221 P SL P P SS S A S ++S + P +Q L PS + P Sbjct: 355 SPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQAL-PSYPHSFP 413 Query: 222 PTDPLVVRN 230 P L V N Sbjct: 414 PPTSLSVSN 422 Score = 32.3 bits (72), Expect = 0.35 Identities = 52/229 (22%), Positives = 73/229 (31%), Gaps = 15/229 (6%) Query: 10 RAKMISQLARTARASCPLHGRTGPMRFSNDEEPEGCGAP-------HLPPRPSPTLPTLY 62 +++ ++ AR AS P + G ++ E E AP LP SP+ Sbjct: 49 KSRQTAKKARVEEASTPKVNKQGRSEEISESESEETNAPKKTKTEQELPRPQSPSDLDSL 108 Query: 63 PVSSTHSSPSPDVAELWTGGTVAWESALEGGLGPVDSELWPTVGVASLP-----PPPIAP 117 S + S D ++ S G DS+ + G++ P PPP+ P Sbjct: 109 DGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSD--SSSGLSQGPARPYHPPPLFP 166 Query: 118 LPEMKGNDSPLQPGTPTFPTPGPGLWDLQTVAVWGTFLPTTLTDLGHTPEPALNPGPKGQ 177 + +P QP P P T P P L PG G Sbjct: 167 PSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGG 226 Query: 178 PESLSPEVPLSSRLLSMPAWDSPANSHRAPETQ-PLPPSLAEAGPPTDP 225 S P P S + H P T + S A PPT P Sbjct: 227 VLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKP 275 >gi|55750041 atrophin-1 [Homo sapiens] Length = 1190 Score = 42.0 bits (97), Expect = 4e-04 Identities = 52/183 (28%), Positives = 70/183 (38%), Gaps = 21/183 (11%) Query: 42 PEGCGAPHLPPRPSPTLPTLYPVSSTHSSPSPDVAELWTGGTVAWESALEGGLGPVDSEL 101 P P P P P +PT+ S+T S+ VA G +++A G P Sbjct: 588 PSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAG----YKTASPPGPPPYGKRA 643 Query: 102 WPTVGVASLPPPPIAPLPEMKGNDSPLQPGTPTFPTPGPGLWDLQTVAVWGTFLPTTLTD 161 + PP P G+ + GTP PG A GTF P + T Sbjct: 644 PSPGAYKTATPPGYKP-----GSPPSFRTGTP------PGYRGTSPPAGPGTFKPGSPT- 691 Query: 162 LGHTPEPALNPGPKGQPE-SLSPEVPLSSRLLS-MPAWDSPANSHRAPETQPLPPSLAEA 219 +G P P GP G P P P S LS PA + PE+ P+PP+ + + Sbjct: 692 VG--PGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPES-PVPPARSPS 748 Query: 220 GPP 222 PP Sbjct: 749 PPP 751 Score = 37.0 bits (84), Expect = 0.014 Identities = 66/249 (26%), Positives = 81/249 (32%), Gaps = 40/249 (16%) Query: 19 RTARASCPLHGRTGPMRFSNDEEPEGCGAPHLPPRPSPTLPTLYPVSSTHSSPSPDVAEL 78 R AS H P + EP PP P P LYP + P + Sbjct: 177 RQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPK 236 Query: 79 WTGGTVAWESALEGGL--GPVDSELWPTVGVASLPPPPIAPLPEMKGNDSPLQPGTPTFP 136 GG + GG P + + + AS PP P + G + P P FP Sbjct: 237 -GGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFP 295 Query: 137 ------TPGPGLWDLQTVAVWGTFLPTTLTDLGHTPEP--------ALNPGP-KG----- 176 P P L L + L GH P P L PGP KG Sbjct: 296 HVTPNLPPPPALRPLNNASASPPGLGAQPLP-GHLPSPHAMGQGMGGLPPGPEKGPTLAP 354 Query: 177 QPESLSP----------EVPLSSRLLSMPAWDSPANSHRA-----PETQPLPPSLAEAGP 221 P SL P P SS S A S ++S + P +Q L PS + P Sbjct: 355 SPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQAL-PSYPHSFP 413 Query: 222 PTDPLVVRN 230 P L V N Sbjct: 414 PPTSLSVSN 422 Score = 32.3 bits (72), Expect = 0.35 Identities = 52/229 (22%), Positives = 73/229 (31%), Gaps = 15/229 (6%) Query: 10 RAKMISQLARTARASCPLHGRTGPMRFSNDEEPEGCGAP-------HLPPRPSPTLPTLY 62 +++ ++ AR AS P + G ++ E E AP LP SP+ Sbjct: 49 KSRQTAKKARVEEASTPKVNKQGRSEEISESESEETNAPKKTKTEQELPRPQSPSDLDSL 108 Query: 63 PVSSTHSSPSPDVAELWTGGTVAWESALEGGLGPVDSELWPTVGVASLP-----PPPIAP 117 S + S D ++ S G DS+ + G++ P PPP+ P Sbjct: 109 DGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSD--SSSGLSQGPARPYHPPPLFP 166 Query: 118 LPEMKGNDSPLQPGTPTFPTPGPGLWDLQTVAVWGTFLPTTLTDLGHTPEPALNPGPKGQ 177 + +P QP P P T P P L PG G Sbjct: 167 PSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGG 226 Query: 178 PESLSPEVPLSSRLLSMPAWDSPANSHRAPETQ-PLPPSLAEAGPPTDP 225 S P P S + H P T + S A PPT P Sbjct: 227 VLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKP 275 >gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] Length = 2426 Score = 42.0 bits (97), Expect = 4e-04 Identities = 36/115 (31%), Positives = 48/115 (41%), Gaps = 20/115 (17%) Query: 110 LPPPPIAPLPEMKGNDSPLQPGTPTFPTPGPGLWDLQTVAVWGTFLPTTLTDLGHTPEPA 169 LP PP +PE++G P TP PGP + LP L+ TP P Sbjct: 383 LPGPPATSMPELQG-----PPVTPVLELPGPSATPVPE-------LPGPLS----TPVPE 426 Query: 170 LNPGPKGQ--PESLSPEV-PLSSRLLSMPAWDSPANSHRAPETQPLPPSLAEAGP 221 L PGP PE P V P+ +P +P+ P+ P PP +A+ P Sbjct: 427 L-PGPPATAVPELPGPSVTPVPQLSQELPGLPAPSMGLEPPQEVPEPPVMAQELP 480 Score = 28.9 bits (63), Expect = 3.9 Identities = 22/79 (27%), Positives = 29/79 (36%), Gaps = 1/79 (1%) Query: 39 DEEPEGCGAPHLPPRPSPTLPTLYPVSSTHSSPSPDVAELWTGGTVAWESALEG-GLGPV 97 D E P LPP PT+P L P + P P +SAL P Sbjct: 1138 DTYTEAYMVPPLPPEEPPTMPPLPPEEPPMTPPLPPEEPPEGPALPTEQSALTAENTWPT 1197 Query: 98 DSELWPTVGVASLPPPPIA 116 + P+ S P PP++ Sbjct: 1198 EVPSSPSEESVSQPEPPVS 1216 >gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] Length = 2303 Score = 42.0 bits (97), Expect = 4e-04 Identities = 36/115 (31%), Positives = 48/115 (41%), Gaps = 20/115 (17%) Query: 110 LPPPPIAPLPEMKGNDSPLQPGTPTFPTPGPGLWDLQTVAVWGTFLPTTLTDLGHTPEPA 169 LP PP +PE++G P TP PGP + LP L+ TP P Sbjct: 383 LPGPPATSMPELQG-----PPVTPVLELPGPSATPVPE-------LPGPLS----TPVPE 426 Query: 170 LNPGPKGQ--PESLSPEV-PLSSRLLSMPAWDSPANSHRAPETQPLPPSLAEAGP 221 L PGP PE P V P+ +P +P+ P+ P PP +A+ P Sbjct: 427 L-PGPPATAVPELPGPSVTPVPQLSQELPGLPAPSMGLEPPQEVPEPPVMAQELP 480 Score = 28.9 bits (63), Expect = 3.9 Identities = 22/79 (27%), Positives = 29/79 (36%), Gaps = 1/79 (1%) Query: 39 DEEPEGCGAPHLPPRPSPTLPTLYPVSSTHSSPSPDVAELWTGGTVAWESALEG-GLGPV 97 D E P LPP PT+P L P + P P +SAL P Sbjct: 1138 DTYTEAYMVPPLPPEEPPTMPPLPPEEPPMTPPLPPEEPPEGPALPTEQSALTAENTWPT 1197 Query: 98 DSELWPTVGVASLPPPPIA 116 + P+ S P PP++ Sbjct: 1198 EVPSSPSEESVSQPEPPVS 1216 >gi|41281612 zinc finger protein 828 [Homo sapiens] Length = 812 Score = 41.6 bits (96), Expect = 6e-04 Identities = 53/211 (25%), Positives = 73/211 (34%), Gaps = 23/211 (10%) Query: 32 GPMRFSNDEEPEGCGAPHLPPRPSPTLPTLYPVSSTHSSPSPDVAELWTGGTVAWESALE 91 GP S+ E P +P P PSP S+ +SP P + W+ Sbjct: 238 GPPSASSPESPVLAASPE-PWGPSPAASPESRKSARTTSPEPRKPSP-SESPEPWKPF-- 293 Query: 92 GGLGPVDSELWPTVGVASLPP-PPIAPLPEMKGNDSPLQPGTPTFPTPG--PGLWDLQTV 148 + P P V S P PP +P P + P P P P PG W Sbjct: 294 PAVSPEPRRPAPAVSPGSWKPGPPGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKPIPS 353 Query: 149 AVWGTFLPTTLTDLGHTPEPALNPG----PKGQPESLS---PEVPLSSRLLSMPAWDSPA 201 G + PT +++P P PES PE+ ++ LS W + Sbjct: 354 VSPGPWKPTPSVSSASWKSSSVSPSSWKSPPASPESWKSGPPELRKTAPTLSPEHWKA-- 411 Query: 202 NSHRAPETQPLPPSLAEAGPPTDPLVVRNAG 232 P+ P L + GPP P + AG Sbjct: 412 -------VPPVSPELRKPGPPLSPEIRSPAG 435 >gi|31324577 molecule interacting with Rab13 [Homo sapiens] Length = 863 Score = 41.6 bits (96), Expect = 6e-04 Identities = 64/261 (24%), Positives = 89/261 (34%), Gaps = 65/261 (24%) Query: 13 MISQLARTARASCPLHGRTGPMRFSNDEEPEGCGAPHLPPRPSPTL--------PTLYPV 64 ++ Q ++ + LH P + EG AP P P TL P P Sbjct: 330 LVEQAGSSSLVNGRLHELPVPKPRGTPKPSEGTPAPRKDP-PWITLVQAEPKKKPAPLPP 388 Query: 65 SSTHSSPSPDVAELWTGGT--VAWESALEGGLGPVDSELWPTVGVASLPPPPIAPLPEMK 122 SS+ PS D ++ GGT VA S PT + S P P E K Sbjct: 389 SSSPGPPSQDSRQVENGGTEEVAQPS--------------PTASLESKPYNPFEEEEEDK 434 Query: 123 GNDSPLQPGTPTFPTPGPGLWDLQTVAVWGTFLPTT---------------------LTD 161 ++P P T P G +++ W PT+ + Sbjct: 435 EEEAPAAPSLATSPALGHPESTPKSLHPWYGITPTSSPKTKKRPAPRAPSASPLALHASR 494 Query: 162 LGHTPEPALNPGPKGQPESLS---------------PEVPLSSRLLSMPAWDSPANSHRA 206 L H+ P+ P P ESLS P VP SS ++ A +P N Sbjct: 495 LSHSEPPSATPSPALSVESLSSESASQTAGAELLEPPAVPKSSSEPAVHAPGTPGN---- 550 Query: 207 PETQPLPPSLAEAGPPTDPLV 227 P + SLA +G +P V Sbjct: 551 PVSLSTNSSLASSGELVEPRV 571 Score = 29.6 bits (65), Expect = 2.3 Identities = 33/121 (27%), Positives = 46/121 (38%), Gaps = 10/121 (8%) Query: 112 PPPIAPLPEMKGNDSPLQPGTPTFPTPGPGLWDLQTVAVWGTFLPTTLTDLGHTPEPALN 171 PP P P + P PT P P L V G+ ++L + G E + Sbjct: 296 PPAGRPTPAPRKASESTTPAPPT-PRPRSSLQQENLVEQAGS---SSLVN-GRLHELPV- 349 Query: 172 PGPKGQPESLSPEVPLSSRLLSMPAWDSPANSHRAPETQPLPPSLAEAGPPTDPLVVRNA 231 P P+G P+ S P + P W + + + PLPPS + P D V N Sbjct: 350 PKPRGTPKP-SEGTPAPRK---DPPWITLVQAEPKKKPAPLPPSSSPGPPSQDSRQVENG 405 Query: 232 G 232 G Sbjct: 406 G 406 >gi|146219843 Snf2-related CBP activator protein [Homo sapiens] Length = 3230 Score = 41.2 bits (95), Expect = 8e-04 Identities = 52/212 (24%), Positives = 77/212 (36%), Gaps = 38/212 (17%) Query: 52 PRPSPTLPTLYPVSSTHSSPSPDVAELWTGGTVAWESALEG-GLGPVDSELWPTVGVASL 110 P P PT ++ P S+ ++P+P L + + G+ + P G+ + Sbjct: 1265 PTPGPTPVSVLPSSTPSTTPAPTGLSLPLAANQVPPTMVNNTGVVKIVVRQAPRDGLTPV 1324 Query: 111 PP------PPIAPLPEMKGNDSPLQPGTPTFPTPGPGLWDLQTVAVWGTFLPTTLTDLGH 164 PP PP + LP + L PG PT G + T L L L H Sbjct: 1325 PPLAPAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPT-----LVRPLLKLVH 1379 Query: 165 TPEPALN---------------------PGPKGQPESLSPEVPLSSRL---LSMPAWDSP 200 +P P ++ PGP P + PL+S + +S+P S Sbjct: 1380 SPSPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSL 1439 Query: 201 ANSHRAPETQPLPPSLAEAGPPTDPLVVRNAG 232 S P T P P S P + PL V +G Sbjct: 1440 PIS--VPTTLPAPASAPLTIPISAPLTVSASG 1469 Score = 32.7 bits (73), Expect = 0.27 Identities = 61/224 (27%), Positives = 85/224 (37%), Gaps = 50/224 (22%) Query: 42 PEGCGAPHLPPRPSPTL-PTLYPVSSTHS------SPSPDVAELWTGGTVAWESALEGGL 94 P P L +P P L P S+ S +P+P A L + A AL L Sbjct: 1529 PTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSA-SQALATPL 1587 Query: 95 GPVDSELWPTVGVASLPPPPIAPL----------PEMKGNDSPL-------QPGT----- 132 P+ + T +A P PP+APL P + + +P+ PGT Sbjct: 1588 APMAAP--QTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASA 1645 Query: 133 PTFPTPGPGLWDLQTVAVWGTFLPTTLTDLGHTPEPALNP------GPKGQPESLS---- 182 P P P L T + +P+ L T AL P G ++LS Sbjct: 1646 SPVPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTG 1705 Query: 183 -PEVPLSSRLLSMPAWDSPANSHRAPETQPLPPSLAEAGPPTDP 225 P+ P ++ LS+ +PA+S Q L SLA GPP P Sbjct: 1706 NPQGPFPTQTLSL----TPASSLVPTPAQTL--SLA-PGPPLGP 1742 Score = 30.4 bits (67), Expect = 1.3 Identities = 55/235 (23%), Positives = 82/235 (34%), Gaps = 47/235 (20%) Query: 8 PLRAKMISQLARTARASCPLHGRTGPMRFSNDEEPEGCGAPHLPPRPSPTLPTLYPVSST 67 PL + +Q A A P G + P + + G G P P P+ TL +L P SS Sbjct: 1671 PLPSPASTQTLALAPALAPTLGGSSPSQTLS----LGTGNPQ-GPFPTQTL-SLTPASSL 1724 Query: 68 HSSPSPDVAELWTGGTVAWESALEGGLGPVDSELWPTVGVASLPPPPIAPLPEMKGNDSP 127 +P+ L GP L PT ++ P PP+A Sbjct: 1725 VPTPA---------------QTLSLAPGP---PLGPTQTLSLAPAPPLA----------- 1755 Query: 128 LQPGTPTFPTPGPGLWDLQTVAVWGTFLPTTLTDLGHTPEPALNPGPKG------QPESL 181 P +P P P L + P ++ L +P P GP P S Sbjct: 1756 --PASPVGPAPAHTLTLAPASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLALAPAST 1813 Query: 182 SPEVPLSSRLLSMPAWDSP---ANSHRAPETQPLPPSLA-EAGPPTDPLVVRNAG 232 +S L+ + +P R P ++ P +L +GPP+ P + G Sbjct: 1814 QSPASQASSLVVSASGAAPLPVTMVSRLPVSKDEPDTLTLRSGPPSPPSTATSFG 1868 Score = 28.9 bits (63), Expect = 3.9 Identities = 44/168 (26%), Positives = 55/168 (32%), Gaps = 23/168 (13%) Query: 48 PHLPPRPSPTLPTLYPVSSTHSSPSPDVAELWTGGTVAWESALEGGLGPVDSELWPTV-- 105 P P P P P P S +P P V ++ + S L P P + Sbjct: 1015 PRAPLGPVPVRPPPGPELSAQPTPGP-VPQVLPASLMVSASPAGPPLIPASRPPGPVLLP 1073 Query: 106 ----GVASLPPPPIAPLPEMKGNDSP------LQPGTPT----FPTPGPGLWDL---QTV 148 SLP +PL + G P L+P P P P PG L TV Sbjct: 1074 PLQPNSGSLPQVLPSPLGVLSGTSRPPTPTLSLKPTPPAPVRLSPAPPPGSSSLLKPLTV 1133 Query: 149 AVWGTFLPTTLTDLGHTPEPALN---PGPKGQPESLSPEVPLSSRLLS 193 TF P T T A P P P+ L + +RL S Sbjct: 1134 PPGYTFPPAAATTTSTTTATATTTAVPAPTPAPQRLILSPDMQARLPS 1181 >gi|24308227 zinc finger protein 687 [Homo sapiens] Length = 1237 Score = 41.2 bits (95), Expect = 8e-04 Identities = 56/211 (26%), Positives = 78/211 (36%), Gaps = 51/211 (24%) Query: 29 GRTGPMRFSNDEEPEGCGAPHLPPRPSPTLPTLYPVSSTHSSPSPDVAELWTGGTVAWES 88 G GP R N G G+P P+LP T SP+P +GGT W+ Sbjct: 116 GPVGPHRMQN-----GFGSPE------PSLP------GTPHSPAPP-----SGGT--WKE 151 Query: 89 ALEGGLGPVD--SELWPTVGVASLPPPPIAPLPEMKGNDSPLQPGTPTFPTP-------G 139 G P+D + P G S P PP AP P +G +P P FP+ G Sbjct: 152 KGMEGKTPLDLFAHFGPEPGDHSDPLPPSAPSPTREGALTP-----PPFPSSFELAQENG 206 Query: 140 PGLWDLQTVAVWGTFLPTTLTDLGHTPEPALNPGPKGQPESLSPEVPLSSR--------- 190 PG+ + G + + H P+ G P++ ++P S+ Sbjct: 207 PGMQPPVSSPPLGALKQESCSP--HHPQVLAQQGSGSSPKAT--DIPASASPPPVAGVPF 262 Query: 191 LLSMPAWDSPANSHRAPETQPLPPSLAEAGP 221 P SP S + P QPL + GP Sbjct: 263 FKQSPGHQSPLASPKVPVCQPLKEEDDDEGP 293 Score = 30.4 bits (67), Expect = 1.3 Identities = 49/195 (25%), Positives = 67/195 (34%), Gaps = 36/195 (18%) Query: 37 SNDEEPEGCGAPHLPPRPSPTL---------------PTLYPVSSTHSSPSPDVA--ELW 79 S EE EG G P +P P + P + +S H P PD++ + Sbjct: 29 SGPEENEGPGGPG---KPEPGVGSESEDTAAASAGDGPGVPAQASDHGLPPPDISVVSVI 85 Query: 80 TGGTVAWES--ALEGGLGPVDSELWPTVGVASLPPPPIAPLPEMKGNDSPLQPGTPTFPT 137 TV E AL GG ++ GV P + G+ P PGTP P Sbjct: 86 VKNTVCPEQSEALAGGSAGDGAQ---AAGVTKEGPVGPHRMQNGFGSPEPSLPGTPHSPA 142 Query: 138 -PGPGLWDLQTVAVWGTFLPTTLTDLGHTPEPALNPGPKGQPESLSPEVPLSSRLLSMPA 196 P G W + G T L H P P + L P P +R ++ Sbjct: 143 PPSGGTWKEK-----GMEGKTPLDLFAH-----FGPEPGDHSDPLPPSAPSPTREGALTP 192 Query: 197 WDSPANSHRAPETQP 211 P++ A E P Sbjct: 193 PPFPSSFELAQENGP 207 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.312 0.134 0.437 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 14,465,985 Number of Sequences: 37866 Number of extensions: 1017771 Number of successful extensions: 7134 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 126 Number of HSP's successfully gapped in prelim test: 653 Number of HSP's that attempted gapping in prelim test: 5108 Number of HSP's gapped (non-prelim): 2095 length of query: 232 length of database: 18,247,518 effective HSP length: 99 effective length of query: 133 effective length of database: 14,498,784 effective search space: 1928338272 effective search space used: 1928338272 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.