BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|239756039 PREDICTED: hypothetical protein LOC643677 [Homo sapiens] (6929 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|239756039 PREDICTED: hypothetical protein LOC643677 [Homo sap... 1.375e+04 0.0 gi|239750569 PREDICTED: hypothetical protein LOC643677 [Homo sap... 1.374e+04 0.0 gi|239744870 PREDICTED: hypothetical protein LOC643677 [Homo sap... 1.372e+04 0.0 gi|226246554 hypothetical protein LOC643677 [Homo sapiens] 1.341e+04 0.0 gi|71061468 centromere protein E [Homo sapiens] 68 3e-10 gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 64 7e-09 gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 60 8e-08 gi|13540523 nucleosomal binding protein 1 [Homo sapiens] 59 1e-07 gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 58 3e-07 gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 57 6e-07 gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 57 6e-07 gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 56 1e-06 gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 55 2e-06 gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 55 3e-06 gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 55 3e-06 gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 55 3e-06 gi|221219020 NYD-SP11 protein [Homo sapiens] 54 4e-06 gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 54 4e-06 gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 54 5e-06 gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 54 7e-06 gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 54 7e-06 gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 53 9e-06 gi|4503257 death-domain associated protein isoform a [Homo sapiens] 53 1e-05 gi|215422388 death-domain associated protein isoform a [Homo sap... 53 1e-05 gi|215422366 death-domain associated protein isoform b [Homo sap... 53 1e-05 gi|34878904 synaptonemal complex protein 1 [Homo sapiens] 52 2e-05 gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 52 3e-05 gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 52 3e-05 gi|38569484 kinesin family member 21A [Homo sapiens] 51 4e-05 gi|41322923 plectin 1 isoform 11 [Homo sapiens] 51 4e-05 >gi|239756039 PREDICTED: hypothetical protein LOC643677 [Homo sapiens] Length = 6929 Score = 1.375e+04 bits (35696), Expect = 0.0 Identities = 6929/6929 (100%), Positives = 6929/6929 (100%) Query: 1 MKACASFWKKPTLPEKGSSDVQELQRIGQLLIHLQEKEKRITSSLTSEEKECNFEDRILF 60 MKACASFWKKPTLPEKGSSDVQELQRIGQLLIHLQEKEKRITSSLTSEEKECNFEDRILF Sbjct: 1 MKACASFWKKPTLPEKGSSDVQELQRIGQLLIHLQEKEKRITSSLTSEEKECNFEDRILF 60 Query: 61 SREILWSGTSESEDQVSPSSESHVPSSNGISSSLPLFYSEVEETCLSHTEHPDREYETIQ 120 SREILWSGTSESEDQVSPSSESHVPSSNGISSSLPLFYSEVEETCLSHTEHPDREYETIQ Sbjct: 61 SREILWSGTSESEDQVSPSSESHVPSSNGISSSLPLFYSEVEETCLSHTEHPDREYETIQ 120 Query: 121 FSSKKLFSMMKTNKNKNSGFSSDLSFSASRFTVENEDLDVAPCPLAHLFLSRDQVRLLEE 180 FSSKKLFSMMKTNKNKNSGFSSDLSFSASRFTVENEDLDVAPCPLAHLFLSRDQVRLLEE Sbjct: 121 FSSKKLFSMMKTNKNKNSGFSSDLSFSASRFTVENEDLDVAPCPLAHLFLSRDQVRLLEE 180 Query: 181 NVRNQIPSKPKTKLGSRTTYQCSRSQESLNQNQPSVGMVISVQAQDSFPGQNAFQNQGLY 240 NVRNQIPSKPKTKLGSRTTYQCSRSQESLNQNQPSVGMVISVQAQDSFPGQNAFQNQGLY Sbjct: 181 NVRNQIPSKPKTKLGSRTTYQCSRSQESLNQNQPSVGMVISVQAQDSFPGQNAFQNQGLY 240 Query: 241 EVQFTSQAQYINHNQESIKSQPESKASNFAQPEDVMKKPFSSSTQDSFQSQDLDRNQHFV 300 EVQFTSQAQYINHNQESIKSQPESKASNFAQPEDVMKKPFSSSTQDSFQSQDLDRNQHFV Sbjct: 241 EVQFTSQAQYINHNQESIKSQPESKASNFAQPEDVMKKPFSSSTQDSFQSQDLDRNQHFV 300 Query: 301 EVPSIVEAKYSVKGLESDEHLGEDQHCVWFIDSNKVKYSIKGQDTIFKNAEFLVLTLNPN 360 EVPSIVEAKYSVKGLESDEHLGEDQHCVWFIDSNKVKYSIKGQDTIFKNAEFLVLTLNPN Sbjct: 301 EVPSIVEAKYSVKGLESDEHLGEDQHCVWFIDSNKVKYSIKGQDTIFKNAEFLVLTLNPN 360 Query: 361 LVTEDMPQLRSVKAQGQQQIVSSELNQDSVYSSVPLLSTIKGQKNRRKTPDSKSKLSLNV 420 LVTEDMPQLRSVKAQGQQQIVSSELNQDSVYSSVPLLSTIKGQKNRRKTPDSKSKLSLNV Sbjct: 361 LVTEDMPQLRSVKAQGQQQIVSSELNQDSVYSSVPLLSTIKGQKNRRKTPDSKSKLSLNV 420 Query: 421 PSLKAKKTPTSQVFQITVCHTLKNRNELGCKNNTEKKELHERKDISDIALHLISVSKLIL 480 PSLKAKKTPTSQVFQITVCHTLKNRNELGCKNNTEKKELHERKDISDIALHLISVSKLIL Sbjct: 421 PSLKAKKTPTSQVFQITVCHTLKNRNELGCKNNTEKKELHERKDISDIALHLISVSKLIL 480 Query: 481 PYVKNYSRKQLVKVMPGLIKCGHFLQKQNKSPDTEKINYAGPLEETGISDITKKEKEYDK 540 PYVKNYSRKQLVKVMPGLIKCGHFLQKQNKSPDTEKINYAGPLEETGISDITKKEKEYDK Sbjct: 481 PYVKNYSRKQLVKVMPGLIKCGHFLQKQNKSPDTEKINYAGPLEETGISDITKKEKEYDK 540 Query: 541 ENKRLKNISPKMLPQLEQSFMVNTVQLKAPCLLVETNGKSKESLKDSITQAKGIGITEFH 600 ENKRLKNISPKMLPQLEQSFMVNTVQLKAPCLLVETNGKSKESLKDSITQAKGIGITEFH Sbjct: 541 ENKRLKNISPKMLPQLEQSFMVNTVQLKAPCLLVETNGKSKESLKDSITQAKGIGITEFH 600 Query: 601 VLNSKKPFDLHIPKHKTSLEEAISKPMQKLVSSPEMESNNRMKIQEDLQSSENSHLQLSN 660 VLNSKKPFDLHIPKHKTSLEEAISKPMQKLVSSPEMESNNRMKIQEDLQSSENSHLQLSN Sbjct: 601 VLNSKKPFDLHIPKHKTSLEEAISKPMQKLVSSPEMESNNRMKIQEDLQSSENSHLQLSN 660 Query: 661 GEELPTSTPKTQRCFPRENTQKQKDFLELVLELSNVGLLISLGSKMHKSSEELEAIKIQV 720 GEELPTSTPKTQRCFPRENTQKQKDFLELVLELSNVGLLISLGSKMHKSSEELEAIKIQV Sbjct: 661 GEELPTSTPKTQRCFPRENTQKQKDFLELVLELSNVGLLISLGSKMHKSSEELEAIKIQV 720 Query: 721 NTESVNLKESKPLILNVTEDSDLRESEELECNTGSNITNMHQDKETSDAFHSATYTTISQ 780 NTESVNLKESKPLILNVTEDSDLRESEELECNTGSNITNMHQDKETSDAFHSATYTTISQ Sbjct: 721 NTESVNLKESKPLILNVTEDSDLRESEELECNTGSNITNMHQDKETSDAFHSATYTTISQ 780 Query: 781 LPDTETHSISKAKADTLRIIRLSHSASKQEKLPDEKETQNAEYIDKSCTFKKPQQCDRKE 840 LPDTETHSISKAKADTLRIIRLSHSASKQEKLPDEKETQNAEYIDKSCTFKKPQQCDRKE Sbjct: 781 LPDTETHSISKAKADTLRIIRLSHSASKQEKLPDEKETQNAEYIDKSCTFKKPQQCDRKE 840 Query: 841 QEKEANSELTQGFRFSIHLKQKPKYVKFQMEQISSGSSKAPNKEQEVQPQTLSTQTILEN 900 QEKEANSELTQGFRFSIHLKQKPKYVKFQMEQISSGSSKAPNKEQEVQPQTLSTQTILEN Sbjct: 841 QEKEANSELTQGFRFSIHLKQKPKYVKFQMEQISSGSSKAPNKEQEVQPQTLSTQTILEN 900 Query: 901 SPCPMMDPFQVEKVKQSTDRPTDRESAGDPKNPLTMPENLPVGELLIETTEYSVPFGGNL 960 SPCPMMDPFQVEKVKQSTDRPTDRESAGDPKNPLTMPENLPVGELLIETTEYSVPFGGNL Sbjct: 901 SPCPMMDPFQVEKVKQSTDRPTDRESAGDPKNPLTMPENLPVGELLIETTEYSVPFGGNL 960 Query: 961 QKTTDSHIAEEKEDVKRYLPAVALGSFNNHLLTLPYFKRQEIKKKLSETKSVLSVKYVIM 1020 QKTTDSHIAEEKEDVKRYLPAVALGSFNNHLLTLPYFKRQEIKKKLSETKSVLSVKYVIM Sbjct: 961 QKTTDSHIAEEKEDVKRYLPAVALGSFNNHLLTLPYFKRQEIKKKLSETKSVLSVKYVIM 1020 Query: 1021 KVKKPAISLMPYINICGTSNHRKKMGGNFEIIIKQILQDKIAAGMLLNVIYPPMSILPNT 1080 KVKKPAISLMPYINICGTSNHRKKMGGNFEIIIKQILQDKIAAGMLLNVIYPPMSILPNT Sbjct: 1021 KVKKPAISLMPYINICGTSNHRKKMGGNFEIIIKQILQDKIAAGMLLNVIYPPMSILPNT 1080 Query: 1081 RMYSRLNAENHSHIKLVQEESQIEREEKYPYFINEGNESQNTLDAKLQDEVKGVKETLPK 1140 RMYSRLNAENHSHIKLVQEESQIEREEKYPYFINEGNESQNTLDAKLQDEVKGVKETLPK Sbjct: 1081 RMYSRLNAENHSHIKLVQEESQIEREEKYPYFINEGNESQNTLDAKLQDEVKGVKETLPK 1140 Query: 1141 AVLHDSCNLGLDAHLEKEIKTEKEMHQPIPFTETIIESVVSPIMELSHAENVKSTQKTQT 1200 AVLHDSCNLGLDAHLEKEIKTEKEMHQPIPFTETIIESVVSPIMELSHAENVKSTQKTQT Sbjct: 1141 AVLHDSCNLGLDAHLEKEIKTEKEMHQPIPFTETIIESVVSPIMELSHAENVKSTQKTQT 1200 Query: 1201 DCKCTADSETPSPISGKSLIGDPLNQTRESYIPSNGSDTREMGYCFAEEKTEIPKDLPAT 1260 DCKCTADSETPSPISGKSLIGDPLNQTRESYIPSNGSDTREMGYCFAEEKTEIPKDLPAT Sbjct: 1201 DCKCTADSETPSPISGKSLIGDPLNQTRESYIPSNGSDTREMGYCFAEEKTEIPKDLPAT 1260 Query: 1261 SPETFNYCTPVLSCSKVMKKRVTFALTTSTAKPKCVNTKAVKPSISETVSVTSHRKKSEL 1320 SPETFNYCTPVLSCSKVMKKRVTFALTTSTAKPKCVNTKAVKPSISETVSVTSHRKKSEL Sbjct: 1261 SPETFNYCTPVLSCSKVMKKRVTFALTTSTAKPKCVNTKAVKPSISETVSVTSHRKKSEL 1320 Query: 1321 DFKTKFKKINQTKGLVPECLNTLCSPMHSRLQREFCLPASQLKQGETADKTYTDVFAKNS 1380 DFKTKFKKINQTKGLVPECLNTLCSPMHSRLQREFCLPASQLKQGETADKTYTDVFAKNS Sbjct: 1321 DFKTKFKKINQTKGLVPECLNTLCSPMHSRLQREFCLPASQLKQGETADKTYTDVFAKNS 1380 Query: 1381 ISHDREEKLQDGKEEEHKVLLEAAPQLSQHLGSEAGQMKEIHLESDPVLNCLTLELHING 1440 ISHDREEKLQDGKEEEHKVLLEAAPQLSQHLGSEAGQMKEIHLESDPVLNCLTLELHING Sbjct: 1381 ISHDREEKLQDGKEEEHKVLLEAAPQLSQHLGSEAGQMKEIHLESDPVLNCLTLELHING 1440 Query: 1441 QRLQHQTGFEQTTLETSLQMGPLEAEELQKANETENDIKVLGGPKIPPPKALQALENSDG 1500 QRLQHQTGFEQTTLETSLQMGPLEAEELQKANETENDIKVLGGPKIPPPKALQALENSDG Sbjct: 1441 QRLQHQTGFEQTTLETSLQMGPLEAEELQKANETENDIKVLGGPKIPPPKALQALENSDG 1500 Query: 1501 LILNAYQKDNELVKSDEELNQPGSTNIQVQPQTHFTQTILKSTSCPTLDQFPFEKVESHV 1560 LILNAYQKDNELVKSDEELNQPGSTNIQVQPQTHFTQTILKSTSCPTLDQFPFEKVESHV Sbjct: 1501 LILNAYQKDNELVKSDEELNQPGSTNIQVQPQTHFTQTILKSTSCPTLDQFPFEKVESHV 1560 Query: 1561 RFSPLKSGEAKVDEIIFYAREGGISSDSSHQKEQAGGTEKKETAIFGSCMPALSTPKTTR 1620 RFSPLKSGEAKVDEIIFYAREGGISSDSSHQKEQAGGTEKKETAIFGSCMPALSTPKTTR Sbjct: 1561 RFSPLKSGEAKVDEIIFYAREGGISSDSSHQKEQAGGTEKKETAIFGSCMPALSTPKTTR 1620 Query: 1621 NLKQFSDMKTLVNPKCGIIKAKKPSISYMLNIRAGAGPKRRKELSCNLTTKMKELHQGKK 1680 NLKQFSDMKTLVNPKCGIIKAKKPSISYMLNIRAGAGPKRRKELSCNLTTKMKELHQGKK Sbjct: 1621 NLKQFSDMKTLVNPKCGIIKAKKPSISYMLNIRAGAGPKRRKELSCNLTTKMKELHQGKK 1680 Query: 1681 GVDETYAFLTMTPDINKYSKVETEKDTLREKRLSSTQVKQDTSPHEDSITSRDIKETLLQ 1740 GVDETYAFLTMTPDINKYSKVETEKDTLREKRLSSTQVKQDTSPHEDSITSRDIKETLLQ Sbjct: 1681 GVDETYAFLTMTPDINKYSKVETEKDTLREKRLSSTQVKQDTSPHEDSITSRDIKETLLQ 1740 Query: 1741 DEEQEERKQEPLLKVIPQHLQHFMFRSGQGKDLDFHKLENQGSRKILFVTKQDVPQQLQP 1800 DEEQEERKQEPLLKVIPQHLQHFMFRSGQGKDLDFHKLENQGSRKILFVTKQDVPQQLQP Sbjct: 1741 DEEQEERKQEPLLKVIPQHLQHFMFRSGQGKDLDFHKLENQGSRKILFVTKQDVPQQLQP 1800 Query: 1801 AEPIQREETKKCLQTQNGTICTVNSKLLPLKSEDSVNGEVLTGAIKRGVPTDRKCMGEQH 1860 AEPIQREETKKCLQTQNGTICTVNSKLLPLKSEDSVNGEVLTGAIKRGVPTDRKCMGEQH Sbjct: 1801 AEPIQREETKKCLQTQNGTICTVNSKLLPLKSEDSVNGEVLTGAIKRGVPTDRKCMGEQH 1860 Query: 1861 NSGKGEKAEFNKDLQATVLELQKSPHGGEAQKANLTDMESGSSNAMNMNVQHEREDKNIQ 1920 NSGKGEKAEFNKDLQATVLELQKSPHGGEAQKANLTDMESGSSNAMNMNVQHEREDKNIQ Sbjct: 1861 NSGKGEKAEFNKDLQATVLELQKSPHGGEAQKANLTDMESGSSNAMNMNVQHEREDKNIQ 1920 Query: 1921 KMLTESVPCYSQHLRFSTHQMKDPDPCKSGSEPKSPEGRSWNLSHIVQKTKQETHFRETV 1980 KMLTESVPCYSQHLRFSTHQMKDPDPCKSGSEPKSPEGRSWNLSHIVQKTKQETHFRETV Sbjct: 1921 KMLTESVPCYSQHLRFSTHQMKDPDPCKSGSEPKSPEGRSWNLSHIVQKTKQETHFRETV 1980 Query: 1981 LEPISGYMMKQSPHMQEGIKCMEGLKTSFPKTGKSKIGSIPRDTPWDENPRRKWDSSISQ 2040 LEPISGYMMKQSPHMQEGIKCMEGLKTSFPKTGKSKIGSIPRDTPWDENPRRKWDSSISQ Sbjct: 1981 LEPISGYMMKQSPHMQEGIKCMEGLKTSFPKTGKSKIGSIPRDTPWDENPRRKWDSSISQ 2040 Query: 2041 KTAWNQKNLQTVLKPLDFSSLMSSEYESRSYTLEFIGKKSMSPKCVTLKAKQLRILQLFN 2100 KTAWNQKNLQTVLKPLDFSSLMSSEYESRSYTLEFIGKKSMSPKCVTLKAKQLRILQLFN Sbjct: 2041 KTAWNQKNLQTVLKPLDFSSLMSSEYESRSYTLEFIGKKSMSPKCVTLKAKQLRILQLFN 2100 Query: 2101 IIRYSTENHRKKKQHRFKYKMKGKQWYTSIGEALLSATEYAKSTTSKSMIDKLLYNTAAR 2160 IIRYSTENHRKKKQHRFKYKMKGKQWYTSIGEALLSATEYAKSTTSKSMIDKLLYNTAAR Sbjct: 2101 IIRYSTENHRKKKQHRFKYKMKGKQWYTSIGEALLSATEYAKSTTSKSMIDKLLYNTAAR 2160 Query: 2161 CILSNRTRRQNLDGHITEEKEEVQENVAAIFLGLLDFFMPVLSDSKNQRNTAQLSEKEII 2220 CILSNRTRRQNLDGHITEEKEEVQENVAAIFLGLLDFFMPVLSDSKNQRNTAQLSEKEII Sbjct: 2161 CILSNRTRRQNLDGHITEEKEEVQENVAAIFLGLLDFFMPVLSDSKNQRNTAQLSEKEII 2220 Query: 2221 FNAKCLTMKEKKSSISQIHKINRESTRKHRKKCKSYLKTVSNRKCQENHGHITEEEEEVQ 2280 FNAKCLTMKEKKSSISQIHKINRESTRKHRKKCKSYLKTVSNRKCQENHGHITEEEEEVQ Sbjct: 2221 FNAKCLTMKEKKSSISQIHKINRESTRKHRKKCKSYLKTVSNRKCQENHGHITEEEEEVQ 2280 Query: 2281 ENSPATFLGPLDFFMPVLSDSKNQINTIQLSERKIILNPKCLTMKEKKPPISQIHKISRQ 2340 ENSPATFLGPLDFFMPVLSDSKNQINTIQLSERKIILNPKCLTMKEKKPPISQIHKISRQ Sbjct: 2281 ENSPATFLGPLDFFMPVLSDSKNQINTIQLSERKIILNPKCLTMKEKKPPISQIHKISRQ 2340 Query: 2341 FTTKHRKKLESNLKTKLKAMWQGENVADTFPNTTSFTPDSSDIKRQSGFQTEIDMRISGL 2400 FTTKHRKKLESNLKTKLKAMWQGENVADTFPNTTSFTPDSSDIKRQSGFQTEIDMRISGL Sbjct: 2341 FTTKHRKKLESNLKTKLKAMWQGENVADTFPNTTSFTPDSSDIKRQSGFQTEIDMRISGL 2400 Query: 2401 SHTQPTQIESLAEGIARYSDPIDKRRTSNLVKGAKLHDRESGEEKQEHLTEMDPFYAENF 2460 SHTQPTQIESLAEGIARYSDPIDKRRTSNLVKGAKLHDRESGEEKQEHLTEMDPFYAENF Sbjct: 2401 SHTQPTQIESLAEGIARYSDPIDKRRTSNLVKGAKLHDRESGEEKQEHLTEMDPFYAENF 2460 Query: 2461 MANTYLRKDRHLGKSEDVLLGETFFSKSQIYKGNSEKNVKIEKNKNGKESLKVGLARMEK 2520 MANTYLRKDRHLGKSEDVLLGETFFSKSQIYKGNSEKNVKIEKNKNGKESLKVGLARMEK Sbjct: 2461 MANTYLRKDRHLGKSEDVLLGETFFSKSQIYKGNSEKNVKIEKNKNGKESLKVGLARMEK 2520 Query: 2521 SDNCAELSEATDDAISNKYDKQNIGHSVLKENAFCNLAAIVPDSVGRHSPASEEMKRQNG 2580 SDNCAELSEATDDAISNKYDKQNIGHSVLKENAFCNLAAIVPDSVGRHSPASEEMKRQNG Sbjct: 2521 SDNCAELSEATDDAISNKYDKQNIGHSVLKENAFCNLAAIVPDSVGRHSPASEEMKRQNG 2580 Query: 2581 RLKMADRSSPQGRPLQAKQSAVSQSPDTAGYAVVSNNKEQKQNFKAQKTEAEVDLIDQEA 2640 RLKMADRSSPQGRPLQAKQSAVSQSPDTAGYAVVSNNKEQKQNFKAQKTEAEVDLIDQEA Sbjct: 2581 RLKMADRSSPQGRPLQAKQSAVSQSPDTAGYAVVSNNKEQKQNFKAQKTEAEVDLIDQEA 2640 Query: 2641 KINVAEEFNPESVFFSKIHPLQIENKKEFKTADWKTRADPKTFALPKKQQELCVSGTIWS 2700 KINVAEEFNPESVFFSKIHPLQIENKKEFKTADWKTRADPKTFALPKKQQELCVSGTIWS Sbjct: 2641 KINVAEEFNPESVFFSKIHPLQIENKKEFKTADWKTRADPKTFALPKKQQELCVSGTIWS 2700 Query: 2701 YPNPYTSISPKIIRHKDKAKTADVESTMHTKQIKLKAKRIPVSQLLEYGTASNKKELRGN 2760 YPNPYTSISPKIIRHKDKAKTADVESTMHTKQIKLKAKRIPVSQLLEYGTASNKKELRGN Sbjct: 2701 YPNPYTSISPKIIRHKDKAKTADVESTMHTKQIKLKAKRIPVSQLLEYGTASNKKELRGN 2760 Query: 2761 IQQQKSFQLSKNAVHRVLKAVYDSGYCVSSIKKLTEVKMEKDKPKDRTCILPQPKLEKPL 2820 IQQQKSFQLSKNAVHRVLKAVYDSGYCVSSIKKLTEVKMEKDKPKDRTCILPQPKLEKPL Sbjct: 2761 IQQQKSFQLSKNAVHRVLKAVYDSGYCVSSIKKLTEVKMEKDKPKDRTCILPQPKLEKPL 2820 Query: 2821 KEMQRSLSGCTDMSSILRKQEQDIREKEQKHQSISEDISQYYIGPLRISSQQINYSSFDA 2880 KEMQRSLSGCTDMSSILRKQEQDIREKEQKHQSISEDISQYYIGPLRISSQQINYSSFDA Sbjct: 2821 KEMQRSLSGCTDMSSILRKQEQDIREKEQKHQSISEDISQYYIGPLRISSQQINYSSFDA 2880 Query: 2881 PRIRTDEELEFLIAQRAKEKDVGIAKHSVSIPWEREGSKRLDIPLNSKGQNIFFTELDTS 2940 PRIRTDEELEFLIAQRAKEKDVGIAKHSVSIPWEREGSKRLDIPLNSKGQNIFFTELDTS Sbjct: 2881 PRIRTDEELEFLIAQRAKEKDVGIAKHSVSIPWEREGSKRLDIPLNSKGQNIFFTELDTS 2940 Query: 2941 QQKICQEQELLKQEDISMTNLGSMACPIMEPLHLENTGKVTEEEDVYINRKISSHVLGKE 3000 QQKICQEQELLKQEDISMTNLGSMACPIMEPLHLENTGKVTEEEDVYINRKISSHVLGKE Sbjct: 2941 QQKICQEQELLKQEDISMTNLGSMACPIMEPLHLENTGKVTEEEDVYINRKISSHVLGKE 3000 Query: 3001 GLKETDIFVGSKGQKFLCTNSEVQHKVPAEQKEQVNPDHVPESILDSESFLSKDPLHLKQ 3060 GLKETDIFVGSKGQKFLCTNSEVQHKVPAEQKEQVNPDHVPESILDSESFLSKDPLHLKQ Sbjct: 3001 GLKETDIFVGSKGQKFLCTNSEVQHKVPAEQKEQVNPDHVPESILDSESFLSKDPLHLKQ 3060 Query: 3061 AVNTARKENVTISESFNENLWGKEQSKLDITLKSNRQKMDFSKKLRMKHLSNYYQNKENI 3120 AVNTARKENVTISESFNENLWGKEQSKLDITLKSNRQKMDFSKKLRMKHLSNYYQNKENI Sbjct: 3061 AVNTARKENVTISESFNENLWGKEQSKLDITLKSNRQKMDFSKKLRMKHLSNYYQNKENI 3120 Query: 3121 LESVLPCILHQLYIENPKKEGSAEEIMSSKVLSPMVEKASHEVGIPVDQPPCSEGIHLNI 3180 LESVLPCILHQLYIENPKKEGSAEEIMSSKVLSPMVEKASHEVGIPVDQPPCSEGIHLNI Sbjct: 3121 LESVLPCILHQLYIENPKKEGSAEEIMSSKVLSPMVEKASHEVGIPVDQPPCSEGIHLNI 3180 Query: 3181 KGRKEHPQESTHEAFPASVSHSLMDVLQIKSPKVKKALKAINSLGYLTSNTKGIGLLFPR 3240 KGRKEHPQESTHEAFPASVSHSLMDVLQIKSPKVKKALKAINSLGYLTSNTKGIGLLFPR Sbjct: 3181 KGRKEHPQESTHEAFPASVSHSLMDVLQIKSPKVKKALKAINSLGYLTSNTKGIGLLFPR 3240 Query: 3241 QAEKEEKYTYKALPKPASHSKTDLFQFNASMQQEKLDAMDIPHYDYLTSQTREAVKQMDV 3300 QAEKEEKYTYKALPKPASHSKTDLFQFNASMQQEKLDAMDIPHYDYLTSQTREAVKQMDV Sbjct: 3241 QAEKEEKYTYKALPKPASHSKTDLFQFNASMQQEKLDAMDIPHYDYLTSQTREAVKQMDV 3300 Query: 3301 IVGYTQNSKKRQDLLKTGQKWQYLPISYENFWEHISCPQKYPCLLQHLMPQEKEALSEGG 3360 IVGYTQNSKKRQDLLKTGQKWQYLPISYENFWEHISCPQKYPCLLQHLMPQEKEALSEGG Sbjct: 3301 IVGYTQNSKKRQDLLKTGQKWQYLPISYENFWEHISCPQKYPCLLQHLMPQEKEALSEGG 3360 Query: 3361 NLSSRTPGLDLFSADQLSTITKNRLEWIVPLISPRQMKKQDSMLPLGSYHKTIKYASLLF 3420 NLSSRTPGLDLFSADQLSTITKNRLEWIVPLISPRQMKKQDSMLPLGSYHKTIKYASLLF Sbjct: 3361 NLSSRTPGLDLFSADQLSTITKNRLEWIVPLISPRQMKKQDSMLPLGSYHKTIKYASLLF 3420 Query: 3421 PKGMKSSDGVQVFDLISNNSSPKLRLGKKIETQKANEKVQKEVCLPITLHSLSASMPILQ 3480 PKGMKSSDGVQVFDLISNNSSPKLRLGKKIETQKANEKVQKEVCLPITLHSLSASMPILQ Sbjct: 3421 PKGMKSSDGVQVFDLISNNSSPKLRLGKKIETQKANEKVQKEVCLPITLHSLSASMPILQ 3480 Query: 3481 ESKGQKDSVEQVIRKGVICHKRRTSKWKKSVFSHILNTSDCGASSNRLEMQWNMTDKMVN 3540 ESKGQKDSVEQVIRKGVICHKRRTSKWKKSVFSHILNTSDCGASSNRLEMQWNMTDKMVN Sbjct: 3481 ESKGQKDSVEQVIRKGVICHKRRTSKWKKSVFSHILNTSDCGASSNRLEMQWNMTDKMVN 3540 Query: 3541 VKHRMSEIDLVAAKICESILSLPHFKLNKETIDGVISSNVKSTKQHISQGKNDRVKAMDM 3600 VKHRMSEIDLVAAKICESILSLPHFKLNKETIDGVISSNVKSTKQHISQGKNDRVKAMDM Sbjct: 3541 VKHRMSEIDLVAAKICESILSLPHFKLNKETIDGVISSNVKSTKQHISQGKNDRVKAMDM 3600 Query: 3601 KRIKSPNIILKPRKSSLSHILSIKEFPLLLDIIKQEGKMQEGKGKSSMKLTNLCTSLPSL 3660 KRIKSPNIILKPRKSSLSHILSIKEFPLLLDIIKQEGKMQEGKGKSSMKLTNLCTSLPSL Sbjct: 3601 KRIKSPNIILKPRKSSLSHILSIKEFPLLLDIIKQEGKMQEGKGKSSMKLTNLCTSLPSL 3660 Query: 3661 SHSNSNSRTKAGKDKSGTLKGCLPPLKLQASSNARRVSSAESINRDSLSNVIESKCFPQK 3720 SHSNSNSRTKAGKDKSGTLKGCLPPLKLQASSNARRVSSAESINRDSLSNVIESKCFPQK Sbjct: 3661 SHSNSNSRTKAGKDKSGTLKGCLPPLKLQASSNARRVSSAESINRDSLSNVIESKCFPQK 3720 Query: 3721 KKEDRENIVDVKDIMGLKCITLKGKKSLFRHLLHGKEPQRSNKKLEKMTQEDESNLNVVQ 3780 KKEDRENIVDVKDIMGLKCITLKGKKSLFRHLLHGKEPQRSNKKLEKMTQEDESNLNVVQ Sbjct: 3721 KKEDRENIVDVKDIMGLKCITLKGKKSLFRHLLHGKEPQRSNKKLEKMTQEDESNLNVVQ 3780 Query: 3781 NKLCASILSPPHLEWNPRIKEVYMRGITRFCLSSSTQQELSDTMEKCEQPIDDSLSSIEK 3840 NKLCASILSPPHLEWNPRIKEVYMRGITRFCLSSSTQQELSDTMEKCEQPIDDSLSSIEK Sbjct: 3781 NKLCASILSPPHLEWNPRIKEVYMRGITRFCLSSSTQQELSDTMEKCEQPIDDSLSSIEK 3840 Query: 3841 AKHMPQKDKDRVEKALEKIMHSKRIALEVKQPSIFQELELNIKEKGGKIQEDKEVEIWSK 3900 AKHMPQKDKDRVEKALEKIMHSKRIALEVKQPSIFQELELNIKEKGGKIQEDKEVEIWSK Sbjct: 3841 AKHMPQKDKDRVEKALEKIMHSKRIALEVKQPSIFQELELNIKEKGGKIQEDKEVEIWSK 3900 Query: 3901 PFASISFLPYSKVGTIEGEEAMRIKMRSSFSQPNLQESSDTEKTAYEKCISDNISNSVKK 3960 PFASISFLPYSKVGTIEGEEAMRIKMRSSFSQPNLQESSDTEKTAYEKCISDNISNSVKK Sbjct: 3901 PFASISFLPYSKVGTIEGEEAMRIKMRSSFSQPNLQESSDTEKTAYEKCISDNISNSVKK 3960 Query: 3961 ALESILQKEQRQKMEKIRALKKMKSSISQGIQLDIKEQEKRIEHIKGEPSVLLTNACASI 4020 ALESILQKEQRQKMEKIRALKKMKSSISQGIQLDIKEQEKRIEHIKGEPSVLLTNACASI Sbjct: 3961 ALESILQKEQRQKMEKIRALKKMKSSISQGIQLDIKEQEKRIEHIKGEPSVLLTNACASI 4020 Query: 4021 PSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEAGEKADGVASKGDITIKVQKAKDY 4080 PSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEAGEKADGVASKGDITIKVQKAKDY Sbjct: 4021 PSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEAGEKADGVASKGDITIKVQKAKDY 4080 Query: 4081 MQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPLNTKEPGKMDQEAQEQGKEDREGE 4140 MQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPLNTKEPGKMDQEAQEQGKEDREGE Sbjct: 4081 MQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPLNTKEPGKMDQEAQEQGKEDREGE 4140 Query: 4141 EQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADGVGIEQGKMDGDKNEQERVLFLYL 4200 EQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADGVGIEQGKMDGDKNEQERVLFLYL Sbjct: 4141 EQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADGVGIEQGKMDGDKNEQERVLFLYL 4200 Query: 4201 PSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSSETGKKANGVPSEGDSASEVQKA 4260 PSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSSETGKKANGVPSEGDSASEVQKA Sbjct: 4201 PSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSSETGKKANGVPSEGDSASEVQKA 4260 Query: 4261 KDYMQQKEEDESKQETVLFLHLPSESSLTCYELNTRKEGEEDLQGIIKSATLQLRQQKSF 4320 KDYMQQKEEDESKQETVLFLHLPSESSLTCYELNTRKEGEEDLQGIIKSATLQLRQQKSF Sbjct: 4261 KDYMQQKEEDESKQETVLFLHLPSESSLTCYELNTRKEGEEDLQGIIKSATLQLRQQKSF 4320 Query: 4321 DAGKIAHTKSFGVDSSNDVKTVQEYKPQKEVDRGKTVSVDYIMQPEGTIFEAEQLSLPHT 4380 DAGKIAHTKSFGVDSSNDVKTVQEYKPQKEVDRGKTVSVDYIMQPEGTIFEAEQLSLPHT Sbjct: 4321 DAGKIAHTKSFGVDSSNDVKTVQEYKPQKEVDRGKTVSVDYIMQPEGTIFEAEQLSLPHT 4380 Query: 4381 LNIPGSSGSKTREVLTNIKEKLRHVQERKSELDVFLTIPSLSHCKLDKRTAGKKEEQGVT 4440 LNIPGSSGSKTREVLTNIKEKLRHVQERKSELDVFLTIPSLSHCKLDKRTAGKKEEQGVT Sbjct: 4381 LNIPGSSGSKTREVLTNIKEKLRHVQERKSELDVFLTIPSLSHCKLDKRTAGKKEEQGVT 4440 Query: 4441 RSFLPPSWHMESSDTGKLKYTLSYLNDITGDSNRTKYMAQIQKDKANISEKSVMHPEYIA 4500 RSFLPPSWHMESSDTGKLKYTLSYLNDITGDSNRTKYMAQIQKDKANISEKSVMHPEYIA Sbjct: 4441 RSFLPPSWHMESSDTGKLKYTLSYLNDITGDSNRTKYMAQIQKDKANISEKSVMHPEYIA 4500 Query: 4501 VKAEKSPLSHILKTKELQVNISQQGEKAQEGEVEIVVLLSKTCPFVTSSAFLELDSIKEE 4560 VKAEKSPLSHILKTKELQVNISQQGEKAQEGEVEIVVLLSKTCPFVTSSAFLELDSIKEE Sbjct: 4501 VKAEKSPLSHILKTKELQVNISQQGEKAQEGEVEIVVLLSKTCPFVTSSAFLELDSIKEE 4560 Query: 4561 EGEPRITRSFMPHLEIQESLPSRQTAPTKPTESLVKKEKQLLPQKEDRVQTVSMHGLMHP 4620 EGEPRITRSFMPHLEIQESLPSRQTAPTKPTESLVKKEKQLLPQKEDRVQTVSMHGLMHP Sbjct: 4561 EGEPRITRSFMPHLEIQESLPSRQTAPTKPTESLVKKEKQLLPQKEDRVQTVSMHGLMHP 4620 Query: 4621 NGAVFKAKTSAPPQVFSITEHSPLSKRKEPQWGMKERAGQKQDRTGRPHVILTKTHPFMP 4680 NGAVFKAKTSAPPQVFSITEHSPLSKRKEPQWGMKERAGQKQDRTGRPHVILTKTHPFMP Sbjct: 4621 NGAVFKAKTSAPPQVFSITEHSPLSKRKEPQWGMKERAGQKQDRTGRPHVILTKTHPFMP 4680 Query: 4681 SLSHHRFSPSQPKLPISSGAGKSRLANSNEGISSHKVILKANQQMPYKEAKDRVKIEGRE 4740 SLSHHRFSPSQPKLPISSGAGKSRLANSNEGISSHKVILKANQQMPYKEAKDRVKIEGRE Sbjct: 4681 SLSHHRFSPSQPKLPISSGAGKSRLANSNEGISSHKVILKANQQMPYKEAKDRVKIEGRE 4740 Query: 4741 GRILPKRIHLRAEALPLALLCNGKNYSLHIEEQGEGVQESKKEPGVVPRKPASFPPPPFY 4800 GRILPKRIHLRAEALPLALLCNGKNYSLHIEEQGEGVQESKKEPGVVPRKPASFPPPPFY Sbjct: 4741 GRILPKRIHLRAEALPLALLCNGKNYSLHIEEQGEGVQESKKEPGVVPRKPASFPPPPFY 4800 Query: 4801 LNCDTRRNEKEGTLGKTQFSFPPLKIQDSSDSGKKAYTESLHGYTLSNSKGPVQPTAQGE 4860 LNCDTRRNEKEGTLGKTQFSFPPLKIQDSSDSGKKAYTESLHGYTLSNSKGPVQPTAQGE Sbjct: 4801 LNCDTRRNEKEGTLGKTQFSFPPLKIQDSSDSGKKAYTESLHGYTLSNSKGPVQPTAQGE 4860 Query: 4861 EKGGLRIDMEDKMLPKCTDLKAKQLLLSDILNTKKLQWKSKEQKRKIQEDKNKQVKGLPS 4920 EKGGLRIDMEDKMLPKCTDLKAKQLLLSDILNTKKLQWKSKEQKRKIQEDKNKQVKGLPS Sbjct: 4861 EKGGLRIDMEDKMLPKCTDLKAKQLLLSDILNTKKLQWKSKEQKRKIQEDKNKQVKGLPS 4920 Query: 4921 INTSLLTPPYLKFDTTEGQENVIRIAKVSLPQSRSKESSDAGRIACPEATHGELSSDVKQ 4980 INTSLLTPPYLKFDTTEGQENVIRIAKVSLPQSRSKESSDAGRIACPEATHGELSSDVKQ Sbjct: 4921 INTSLLTPPYLKFDTTEGQENVIRIAKVSLPQSRSKESSDAGRIACPEATHGELSSDVKQ 4980 Query: 4981 LKAHLLQKEEKDREKVADMTSVLDPNKMYLKAKKSPVLHTHSFSDLQWKTREQEEEKVQK 5040 LKAHLLQKEEKDREKVADMTSVLDPNKMYLKAKKSPVLHTHSFSDLQWKTREQEEEKVQK Sbjct: 4981 LKAHLLQKEEKDREKVADMTSVLDPNKMYLKAKKSPVLHTHSFSDLQWKTREQEEEKVQK 5040 Query: 5041 VKSGPGVMLSKSPSRSSPLHLNVNTGFQEESIPILTRPSFPLVKLQVSPDTEGGTCIRPI 5100 VKSGPGVMLSKSPSRSSPLHLNVNTGFQEESIPILTRPSFPLVKLQVSPDTEGGTCIRPI Sbjct: 5041 VKSGPGVMLSKSPSRSSPLHLNVNTGFQEESIPILTRPSFPLVKLQVSPDTEGGTCIRPI 5100 Query: 5101 AGDILIYLQKGKHVSQNKEEDDVQIVSILIFPKHQEEKVQECEGEPGVVLTKSTSLPSLS 5160 AGDILIYLQKGKHVSQNKEEDDVQIVSILIFPKHQEEKVQECEGEPGVVLTKSTSLPSLS Sbjct: 5101 AGDILIYLQKGKHVSQNKEEDDVQIVSILIFPKHQEEKVQECEGEPGVVLTKSTSLPSLS 5160 Query: 5161 QLELDKETHLGNEMLRLKRPILRRISHIGETVHRESVVGDIPKDVKNEKQHIPQKEERNQ 5220 QLELDKETHLGNEMLRLKRPILRRISHIGETVHRESVVGDIPKDVKNEKQHIPQKEERNQ Sbjct: 5161 QLELDKETHLGNEMLRLKRPILRRISHIGETVHRESVVGDIPKDVKNEKQHIPQKEERNQ 5220 Query: 5221 KKIIDMRGTDITLKSKKSPRSCMLHRTELHVNIGGQGRKEHEGQDKPPGMIQRKMCILFS 5280 KKIIDMRGTDITLKSKKSPRSCMLHRTELHVNIGGQGRKEHEGQDKPPGMIQRKMCILFS Sbjct: 5221 KKIIDMRGTDITLKSKKSPRSCMLHRTELHVNIGGQGRKEHEGQDKPPGMIQRKMCILFS 5280 Query: 5281 KPLPSNLKLERATHADEERLGGKTSFVLPLMPSALPDTEKTADAEARSGDVRKGKPHRSQ 5340 KPLPSNLKLERATHADEERLGGKTSFVLPLMPSALPDTEKTADAEARSGDVRKGKPHRSQ Sbjct: 5281 KPLPSNLKLERATHADEERLGGKTSFVLPLMPSALPDTEKTADAEARSGDVRKGKPHRSQ 5340 Query: 5341 KENRHEVKTIDMRFRIHCQEARISPMSHILNAKELVLNINKLEKKVHKDKDEACVVLSRT 5400 KENRHEVKTIDMRFRIHCQEARISPMSHILNAKELVLNINKLEKKVHKDKDEACVVLSRT Sbjct: 5341 KENRHEVKTIDMRFRIHCQEARISPMSHILNAKELVLNINKLEKKVHKDKDEACVVLSRT 5400 Query: 5401 FLSIPSAPPLYLDSGNKTDKDTPGITGSSCPQRTLHVPSNTQKITNRDSVEGVDKNVVKQ 5460 FLSIPSAPPLYLDSGNKTDKDTPGITGSSCPQRTLHVPSNTQKITNRDSVEGVDKNVVKQ Sbjct: 5401 FLSIPSAPPLYLDSGNKTDKDTPGITGSSCPQRTLHVPSNTQKITNRDSVEGVDKNVVKQ 5460 Query: 5461 AEQYVPRPEAEQQLTSNFMISVQQRNQPSRVTSEEDLNQLVLNSRDEDIYFTGFGTIRSG 5520 AEQYVPRPEAEQQLTSNFMISVQQRNQPSRVTSEEDLNQLVLNSRDEDIYFTGFGTIRSG Sbjct: 5461 AEQYVPRPEAEQQLTSNFMISVQQRNQPSRVTSEEDLNQLVLNSRDEDIYFTGFGTIRSG 5520 Query: 5521 KRPEWLFTGKKAQPVKYKTETLTAFLSYPTMDATKMGGLEEDTEIMDNLNHKISPKASVS 5580 KRPEWLFTGKKAQPVKYKTETLTAFLSYPTMDATKMGGLEEDTEIMDNLNHKISPKASVS Sbjct: 5521 KRPEWLFTGKKAQPVKYKTETLTAFLSYPTMDATKMGGLEEDTEIMDNLNHKISPKASVS 5580 Query: 5581 LIRKISKELYVTLGTPASSKGFSVSERYAHQQETSSKVSPELAGSCKFDKPKEDGQSNDR 5640 LIRKISKELYVTLGTPASSKGFSVSERYAHQQETSSKVSPELAGSCKFDKPKEDGQSNDR Sbjct: 5581 LIRKISKELYVTLGTPASSKGFSVSERYAHQQETSSKVSPELAGSCKFDKPKEDGQSNDR 5640 Query: 5641 ISKMFSPKVLAPQTKGSLKKISIVTNWNAPQNIEEQDIVMKKQVIRRCEHGHKTRTNTIL 5700 ISKMFSPKVLAPQTKGSLKKISIVTNWNAPQNIEEQDIVMKKQVIRRCEHGHKTRTNTIL Sbjct: 5641 ISKMFSPKVLAPQTKGSLKKISIVTNWNAPQNIEEQDIVMKKQVIRRCEHGHKTRTNTIL 5700 Query: 5701 SKFPLQSGKQKTPSETDVDKKTTAHLSLQMLPGIHMDMTEIDPAKGGRKQALLISEQEEG 5760 SKFPLQSGKQKTPSETDVDKKTTAHLSLQMLPGIHMDMTEIDPAKGGRKQALLISEQEEG Sbjct: 5701 SKFPLQSGKQKTPSETDVDKKTTAHLSLQMLPGIHMDMTEIDPAKGGRKQALLISEQEEG 5760 Query: 5761 VLELLPKSLFPPWTFQFQSGDLEEKHQTDANTNINLEQKKLEMDNDSTVNQKEGKLKIGT 5820 VLELLPKSLFPPWTFQFQSGDLEEKHQTDANTNINLEQKKLEMDNDSTVNQKEGKLKIGT Sbjct: 5761 VLELLPKSLFPPWTFQFQSGDLEEKHQTDANTNINLEQKKLEMDNDSTVNQKEGKLKIGT 5820 Query: 5821 NRALHLQEEKTEMHKARTANLEKERGRMDTSSSAHPHLPSLKAEESQMKTQVITHRENSR 5880 NRALHLQEEKTEMHKARTANLEKERGRMDTSSSAHPHLPSLKAEESQMKTQVITHRENSR Sbjct: 5821 NRALHLQEEKTEMHKARTANLEKERGRMDTSSSAHPHLPSLKAEESQMKTQVITHRENSR 5880 Query: 5881 LIMQKQKKELEASNAKQSIQLQKLFQRNVLDSFYSYVPLSPKCKDQKGRLTIRDLKRELS 5940 LIMQKQKKELEASNAKQSIQLQKLFQRNVLDSFYSYVPLSPKCKDQKGRLTIRDLKRELS Sbjct: 5881 LIMQKQKKELEASNAKQSIQLQKLFQRNVLDSFYSYVPLSPKCKDQKGRLTIRDLKRELS 5940 Query: 5941 TKYLTMKIQNHPIPQMLNITGRGTPSNRKKLEYDVKLKNIASWSKDVSGIFIRSLSISIM 6000 TKYLTMKIQNHPIPQMLNITGRGTPSNRKKLEYDVKLKNIASWSKDVSGIFIRSLSISIM Sbjct: 5941 TKYLTMKIQNHPIPQMLNITGRGTPSNRKKLEYDVKLKNIASWSKDVSGIFIRSLSISIM 6000 Query: 6001 RSPHTDPKTNLEREKRICLPKFQEKSPNTSEMSKRDTLTIVKGEQNFTNTVPQDPQPFAV 6060 RSPHTDPKTNLEREKRICLPKFQEKSPNTSEMSKRDTLTIVKGEQNFTNTVPQDPQPFAV Sbjct: 6001 RSPHTDPKTNLEREKRICLPKFQEKSPNTSEMSKRDTLTIVKGEQNFTNTVPQDPQPFAV 6060 Query: 6061 DKQQMQKLPNVKSEANLRSEMNKKYLKAQTKERIVPEHDVSRIIKKPDLRIIEQEEKILK 6120 DKQQMQKLPNVKSEANLRSEMNKKYLKAQTKERIVPEHDVSRIIKKPDLRIIEQEEKILK Sbjct: 6061 DKQQMQKLPNVKSEANLRSEMNKKYLKAQTKERIVPEHDVSRIIKKPDLRIIEQEEKILK 6120 Query: 6121 RILTPTECPSMLEDPKLPKQRDQSEPVWDMTTQKVQQQKAFPGTVPIPPQVKSSEVKIVA 6180 RILTPTECPSMLEDPKLPKQRDQSEPVWDMTTQKVQQQKAFPGTVPIPPQVKSSEVKIVA Sbjct: 6121 RILTPTECPSMLEDPKLPKQRDQSEPVWDMTTQKVQQQKAFPGTVPIPPQVKSSEVKIVA 6180 Query: 6181 DSTNAEHLLPICEATKAISESQVKNMIQDKVSSDKLDNIQAYKPDDLKSPPFPEGPDTIS 6240 DSTNAEHLLPICEATKAISESQVKNMIQDKVSSDKLDNIQAYKPDDLKSPPFPEGPDTIS Sbjct: 6181 DSTNAEHLLPICEATKAISESQVKNMIQDKVSSDKLDNIQAYKPDDLKSPPFPEGPDTIS 6240 Query: 6241 TAIYPKTQHKSLLEQFTPKEKNKLTSHLESKALEIQLNLIPEMARKSLQMFNFYPKGTIS 6300 TAIYPKTQHKSLLEQFTPKEKNKLTSHLESKALEIQLNLIPEMARKSLQMFNFYPKGTIS Sbjct: 6241 TAIYPKTQHKSLLEQFTPKEKNKLTSHLESKALEIQLNLIPEMARKSLQMFNFYPKGTIS 6300 Query: 6301 KDNSWRFYSRHKTMNFMSLEGTDTIEPNSKHKHQKDSPLASNMKTLIVDVSSDSEETITK 6360 KDNSWRFYSRHKTMNFMSLEGTDTIEPNSKHKHQKDSPLASNMKTLIVDVSSDSEETITK Sbjct: 6301 KDNSWRFYSRHKTMNFMSLEGTDTIEPNSKHKHQKDSPLASNMKTLIVDVSSDSEETITK 6360 Query: 6361 LQSINKLENGTSAVTSASEMLLPHTLQNHSVKEKGKLLMHFSVKTLEIQMKAFPRIVRES 6420 LQSINKLENGTSAVTSASEMLLPHTLQNHSVKEKGKLLMHFSVKTLEIQMKAFPRIVRES Sbjct: 6361 LQSINKLENGTSAVTSASEMLLPHTLQNHSVKEKGKLLMHFSVKTLEIQMKAFPRIVRES 6420 Query: 6421 YAMTSAHERKKPLSNCIHPGFTGPKRQNRILLLSEEKSLHQIDLDLQYKYLRFLLGLPVG 6480 YAMTSAHERKKPLSNCIHPGFTGPKRQNRILLLSEEKSLHQIDLDLQYKYLRFLLGLPVG Sbjct: 6421 YAMTSAHERKKPLSNCIHPGFTGPKRQNRILLLSEEKSLHQIDLDLQYKYLRFLLGLPVG 6480 Query: 6481 STFPKPNVLPKHSKLNTIAVCKNVNAGGQSGSLSIDTELLEQHISFKKQSPHENSSLIRK 6540 STFPKPNVLPKHSKLNTIAVCKNVNAGGQSGSLSIDTELLEQHISFKKQSPHENSSLIRK Sbjct: 6481 STFPKPNVLPKHSKLNTIAVCKNVNAGGQSGSLSIDTELLEQHISFKKQSPHENSSLIRK 6540 Query: 6541 FPQPTLVCASDRDLHSPRKKDTQVLSESEFHVTPEKNKQYHVWFQERNTCESVDLRTQRN 6600 FPQPTLVCASDRDLHSPRKKDTQVLSESEFHVTPEKNKQYHVWFQERNTCESVDLRTQRN Sbjct: 6541 FPQPTLVCASDRDLHSPRKKDTQVLSESEFHVTPEKNKQYHVWFQERNTCESVDLRTQRN 6600 Query: 6601 ATGSAVSCETQISEDFVDIQTDIESPADLDECSCLEVSESEECVFLEANSYLSQESENIL 6660 ATGSAVSCETQISEDFVDIQTDIESPADLDECSCLEVSESEECVFLEANSYLSQESENIL Sbjct: 6601 ATGSAVSCETQISEDFVDIQTDIESPADLDECSCLEVSESEECVFLEANSYLSQESENIL 6660 Query: 6661 FELQTGIPLENVYKITTDLKSFYSEDSGSHCTRECRKETLIITPPSCKSHKSRKYRSSSK 6720 FELQTGIPLENVYKITTDLKSFYSEDSGSHCTRECRKETLIITPPSCKSHKSRKYRSSSK Sbjct: 6661 FELQTGIPLENVYKITTDLKSFYSEDSGSHCTRECRKETLIITPPSCKSHKSRKYRSSSK 6720 Query: 6721 MKSPDWLCHSSSNTAEIQSRSSSVSFSEEKISWTTKSRTSYSSAPLTESNIKSHLAKNQG 6780 MKSPDWLCHSSSNTAEIQSRSSSVSFSEEKISWTTKSRTSYSSAPLTESNIKSHLAKNQG Sbjct: 6721 MKSPDWLCHSSSNTAEIQSRSSSVSFSEEKISWTTKSRTSYSSAPLTESNIKSHLAKNQG 6780 Query: 6781 KSHRHPESQERKKARSDLFRKNSSHWDHDYSCTHSKGKRDRKKRVYDYESERLDCFQSKH 6840 KSHRHPESQERKKARSDLFRKNSSHWDHDYSCTHSKGKRDRKKRVYDYESERLDCFQSKH Sbjct: 6781 KSHRHPESQERKKARSDLFRKNSSHWDHDYSCTHSKGKRDRKKRVYDYESERLDCFQSKH 6840 Query: 6841 KSASKPHHDDINFYSERKQNRPFFFACVPADSLEVIPKTIRWTIPPETLRKRNFRIPLVA 6900 KSASKPHHDDINFYSERKQNRPFFFACVPADSLEVIPKTIRWTIPPETLRKRNFRIPLVA Sbjct: 6841 KSASKPHHDDINFYSERKQNRPFFFACVPADSLEVIPKTIRWTIPPETLRKRNFRIPLVA 6900 Query: 6901 KISSSWNIWSSSKKLLGSLSGSLTTVFHS 6929 KISSSWNIWSSSKKLLGSLSGSLTTVFHS Sbjct: 6901 KISSSWNIWSSSKKLLGSLSGSLTTVFHS 6929 >gi|239750569 PREDICTED: hypothetical protein LOC643677 [Homo sapiens] Length = 6929 Score = 1.374e+04 bits (35659), Expect = 0.0 Identities = 6924/6929 (99%), Positives = 6925/6929 (99%) Query: 1 MKACASFWKKPTLPEKGSSDVQELQRIGQLLIHLQEKEKRITSSLTSEEKECNFEDRILF 60 MKACASFWKKPTLPEKGSSDVQELQRIGQLLIHLQEKEKRITSSLTSEEKECNFEDRILF Sbjct: 1 MKACASFWKKPTLPEKGSSDVQELQRIGQLLIHLQEKEKRITSSLTSEEKECNFEDRILF 60 Query: 61 SREILWSGTSESEDQVSPSSESHVPSSNGISSSLPLFYSEVEETCLSHTEHPDREYETIQ 120 SREILWSGTSESEDQVSPSSESHVPSSNGISSSLPLFYSEVEETCLSHTEHPDREYETIQ Sbjct: 61 SREILWSGTSESEDQVSPSSESHVPSSNGISSSLPLFYSEVEETCLSHTEHPDREYETIQ 120 Query: 121 FSSKKLFSMMKTNKNKNSGFSSDLSFSASRFTVENEDLDVAPCPLAHLFLSRDQVRLLEE 180 FSSKKLFSMMKTNKNKNSGFSSDLSFSASRFTVENEDLDVAPCPLAHLFLSRDQVRLLEE Sbjct: 121 FSSKKLFSMMKTNKNKNSGFSSDLSFSASRFTVENEDLDVAPCPLAHLFLSRDQVRLLEE 180 Query: 181 NVRNQIPSKPKTKLGSRTTYQCSRSQESLNQNQPSVGMVISVQAQDSFPGQNAFQNQGLY 240 NVRNQIPSKPKTKLGSRTTYQCSRSQESLNQNQPSVGMVISVQAQDSFPGQNAFQNQGLY Sbjct: 181 NVRNQIPSKPKTKLGSRTTYQCSRSQESLNQNQPSVGMVISVQAQDSFPGQNAFQNQGLY 240 Query: 241 EVQFTSQAQYINHNQESIKSQPESKASNFAQPEDVMKKPFSSSTQDSFQSQDLDRNQHFV 300 EVQFTSQAQYINHNQESIKSQPESKASNFAQPEDVMKKPFSSSTQDSFQSQDLDRNQHFV Sbjct: 241 EVQFTSQAQYINHNQESIKSQPESKASNFAQPEDVMKKPFSSSTQDSFQSQDLDRNQHFV 300 Query: 301 EVPSIVEAKYSVKGLESDEHLGEDQHCVWFIDSNKVKYSIKGQDTIFKNAEFLVLTLNPN 360 EVPSIVEAKYSVKGLESDEHLGEDQHCVWFIDSNKVKYSIKGQDTIFKNAEFLVLTLNPN Sbjct: 301 EVPSIVEAKYSVKGLESDEHLGEDQHCVWFIDSNKVKYSIKGQDTIFKNAEFLVLTLNPN 360 Query: 361 LVTEDMPQLRSVKAQGQQQIVSSELNQDSVYSSVPLLSTIKGQKNRRKTPDSKSKLSLNV 420 LVTEDMPQLRSVKAQGQQQIVSSELNQDSVYSSVPLLSTIKGQKNRRKTPDSKSKLSLNV Sbjct: 361 LVTEDMPQLRSVKAQGQQQIVSSELNQDSVYSSVPLLSTIKGQKNRRKTPDSKSKLSLNV 420 Query: 421 PSLKAKKTPTSQVFQITVCHTLKNRNELGCKNNTEKKELHERKDISDIALHLISVSKLIL 480 PSLKAKKTPTSQVFQITVCHTLKNRNELGCKNNTEKKELHERKDISDIALHLISVSKLIL Sbjct: 421 PSLKAKKTPTSQVFQITVCHTLKNRNELGCKNNTEKKELHERKDISDIALHLISVSKLIL 480 Query: 481 PYVKNYSRKQLVKVMPGLIKCGHFLQKQNKSPDTEKINYAGPLEETGISDITKKEKEYDK 540 PYVKNYSRKQLVKVMPGLIKCGHFLQKQNKSPDTEKINYAGPLEETGISDITKKEKEYDK Sbjct: 481 PYVKNYSRKQLVKVMPGLIKCGHFLQKQNKSPDTEKINYAGPLEETGISDITKKEKEYDK 540 Query: 541 ENKRLKNISPKMLPQLEQSFMVNTVQLKAPCLLVETNGKSKESLKDSITQAKGIGITEFH 600 ENKRLKNISPKMLPQLEQSFMVNTVQLKAPCLLVETNGKSKESLKDSITQAKGIGITEFH Sbjct: 541 ENKRLKNISPKMLPQLEQSFMVNTVQLKAPCLLVETNGKSKESLKDSITQAKGIGITEFH 600 Query: 601 VLNSKKPFDLHIPKHKTSLEEAISKPMQKLVSSPEMESNNRMKIQEDLQSSENSHLQLSN 660 VLNSKKPFDLHIPKHKTSLEEAISKPMQKLVSSPEMESNNRMKIQEDLQSSENSHLQLSN Sbjct: 601 VLNSKKPFDLHIPKHKTSLEEAISKPMQKLVSSPEMESNNRMKIQEDLQSSENSHLQLSN 660 Query: 661 GEELPTSTPKTQRCFPRENTQKQKDFLELVLELSNVGLLISLGSKMHKSSEELEAIKIQV 720 GEELPTSTPKTQRCFPRENTQKQKDFLELVLELSNVGLLISLGSKMHKSSEELEAIKIQV Sbjct: 661 GEELPTSTPKTQRCFPRENTQKQKDFLELVLELSNVGLLISLGSKMHKSSEELEAIKIQV 720 Query: 721 NTESVNLKESKPLILNVTEDSDLRESEELECNTGSNITNMHQDKETSDAFHSATYTTISQ 780 NTESVNLKESKPLILNVTEDSDLRESEELECNTGSNITNMHQDKETSDAFHSATYTTISQ Sbjct: 721 NTESVNLKESKPLILNVTEDSDLRESEELECNTGSNITNMHQDKETSDAFHSATYTTISQ 780 Query: 781 LPDTETHSISKAKADTLRIIRLSHSASKQEKLPDEKETQNAEYIDKSCTFKKPQQCDRKE 840 LPDTETHSISKAKADTLRIIRLSHSASKQEKLPDEKETQNAEYIDKSCTFKKPQQCDRKE Sbjct: 781 LPDTETHSISKAKADTLRIIRLSHSASKQEKLPDEKETQNAEYIDKSCTFKKPQQCDRKE 840 Query: 841 QEKEANSELTQGFRFSIHLKQKPKYVKFQMEQISSGSSKAPNKEQEVQPQTLSTQTILEN 900 QEKEANSELTQGFRFSIHLKQKPKYVKFQMEQISSGSSKAPNKEQEVQPQTLSTQTILEN Sbjct: 841 QEKEANSELTQGFRFSIHLKQKPKYVKFQMEQISSGSSKAPNKEQEVQPQTLSTQTILEN 900 Query: 901 SPCPMMDPFQVEKVKQSTDRPTDRESAGDPKNPLTMPENLPVGELLIETTEYSVPFGGNL 960 SPCPMMDPFQVEKVKQSTDRPTDRESAGDPKNPLTMPENLPVGELLIETTEYSVPFGGNL Sbjct: 901 SPCPMMDPFQVEKVKQSTDRPTDRESAGDPKNPLTMPENLPVGELLIETTEYSVPFGGNL 960 Query: 961 QKTTDSHIAEEKEDVKRYLPAVALGSFNNHLLTLPYFKRQEIKKKLSETKSVLSVKYVIM 1020 QKTTDSHIAEEKEDVKRYLPAVALGSFNNHLLTLPYFKRQEIKKKLSETKSVLSVKYVIM Sbjct: 961 QKTTDSHIAEEKEDVKRYLPAVALGSFNNHLLTLPYFKRQEIKKKLSETKSVLSVKYVIM 1020 Query: 1021 KVKKPAISLMPYINICGTSNHRKKMGGNFEIIIKQILQDKIAAGMLLNVIYPPMSILPNT 1080 KVKKPAISLMPYINICGTSNHRKKMGGNFEIIIKQILQDKIAAGMLLNVIYPPMSILPNT Sbjct: 1021 KVKKPAISLMPYINICGTSNHRKKMGGNFEIIIKQILQDKIAAGMLLNVIYPPMSILPNT 1080 Query: 1081 RMYSRLNAENHSHIKLVQEESQIEREEKYPYFINEGNESQNTLDAKLQDEVKGVKETLPK 1140 RMYSRLNAENHSHIKLVQEESQIEREEKYPYFINEGNESQNTLDAKLQDEVKGVKETLPK Sbjct: 1081 RMYSRLNAENHSHIKLVQEESQIEREEKYPYFINEGNESQNTLDAKLQDEVKGVKETLPK 1140 Query: 1141 AVLHDSCNLGLDAHLEKEIKTEKEMHQPIPFTETIIESVVSPIMELSHAENVKSTQKTQT 1200 AVLHDSCNLGLDAHLEKEIKTEKEMHQPIPFTETIIESVVSPIMELSHAENVKSTQKTQT Sbjct: 1141 AVLHDSCNLGLDAHLEKEIKTEKEMHQPIPFTETIIESVVSPIMELSHAENVKSTQKTQT 1200 Query: 1201 DCKCTADSETPSPISGKSLIGDPLNQTRESYIPSNGSDTREMGYCFAEEKTEIPKDLPAT 1260 DCKCTADSETPSPISGKSLIGDPLNQTRESYIPSNGSDTREMGYCFAEEKTEIPKDLPAT Sbjct: 1201 DCKCTADSETPSPISGKSLIGDPLNQTRESYIPSNGSDTREMGYCFAEEKTEIPKDLPAT 1260 Query: 1261 SPETFNYCTPVLSCSKVMKKRVTFALTTSTAKPKCVNTKAVKPSISETVSVTSHRKKSEL 1320 SPETFNYCTPVLSCSKVMKKRVTFALTTSTAKPKCVNTKAVKPSISETVSVTSHRKKSEL Sbjct: 1261 SPETFNYCTPVLSCSKVMKKRVTFALTTSTAKPKCVNTKAVKPSISETVSVTSHRKKSEL 1320 Query: 1321 DFKTKFKKINQTKGLVPECLNTLCSPMHSRLQREFCLPASQLKQGETADKTYTDVFAKNS 1380 DFKTKFKKINQTKGLVPECLNTLCSPMHSRLQREFCLPASQLKQGETADKTYTDVFAKNS Sbjct: 1321 DFKTKFKKINQTKGLVPECLNTLCSPMHSRLQREFCLPASQLKQGETADKTYTDVFAKNS 1380 Query: 1381 ISHDREEKLQDGKEEEHKVLLEAAPQLSQHLGSEAGQMKEIHLESDPVLNCLTLELHING 1440 ISHDREEKLQDGKEEEHKVLLEAAPQLSQHLGSEAGQMKEIHLESDPVLNCLTLELHING Sbjct: 1381 ISHDREEKLQDGKEEEHKVLLEAAPQLSQHLGSEAGQMKEIHLESDPVLNCLTLELHING 1440 Query: 1441 QRLQHQTGFEQTTLETSLQMGPLEAEELQKANETENDIKVLGGPKIPPPKALQALENSDG 1500 QRLQHQTGFEQTTLETSLQMGPLEAEELQKANETENDIKVLGGPKIPPPKALQALENSDG Sbjct: 1441 QRLQHQTGFEQTTLETSLQMGPLEAEELQKANETENDIKVLGGPKIPPPKALQALENSDG 1500 Query: 1501 LILNAYQKDNELVKSDEELNQPGSTNIQVQPQTHFTQTILKSTSCPTLDQFPFEKVESHV 1560 LILNAYQKDNELVKSDEELNQPGSTNIQVQPQTHFTQTILKSTSCPTLDQFPFEKVESHV Sbjct: 1501 LILNAYQKDNELVKSDEELNQPGSTNIQVQPQTHFTQTILKSTSCPTLDQFPFEKVESHV 1560 Query: 1561 RFSPLKSGEAKVDEIIFYAREGGISSDSSHQKEQAGGTEKKETAIFGSCMPALSTPKTTR 1620 RFSPLKSGEAKVDEIIFYAREGGISSDSSHQKEQAGGTEKKETAIFGSCMPALSTPKTTR Sbjct: 1561 RFSPLKSGEAKVDEIIFYAREGGISSDSSHQKEQAGGTEKKETAIFGSCMPALSTPKTTR 1620 Query: 1621 NLKQFSDMKTLVNPKCGIIKAKKPSISYMLNIRAGAGPKRRKELSCNLTTKMKELHQGKK 1680 NLKQFSDMKTLVNPKCGIIKAKKPSISYMLNIRAGAGPKRRKELSCNLTTKMKELHQGKK Sbjct: 1621 NLKQFSDMKTLVNPKCGIIKAKKPSISYMLNIRAGAGPKRRKELSCNLTTKMKELHQGKK 1680 Query: 1681 GVDETYAFLTMTPDINKYSKVETEKDTLREKRLSSTQVKQDTSPHEDSITSRDIKETLLQ 1740 GVDETYAFLTMTPDINKYSKVETEKDTLREKRLSSTQVKQDTSPHEDSITSRDIKETLLQ Sbjct: 1681 GVDETYAFLTMTPDINKYSKVETEKDTLREKRLSSTQVKQDTSPHEDSITSRDIKETLLQ 1740 Query: 1741 DEEQEERKQEPLLKVIPQHLQHFMFRSGQGKDLDFHKLENQGSRKILFVTKQDVPQQLQP 1800 DEEQEERKQEPLLKVIPQHLQHFMFRSGQGKDLDFHKLENQGSRKILFVTKQDVPQQLQP Sbjct: 1741 DEEQEERKQEPLLKVIPQHLQHFMFRSGQGKDLDFHKLENQGSRKILFVTKQDVPQQLQP 1800 Query: 1801 AEPIQREETKKCLQTQNGTICTVNSKLLPLKSEDSVNGEVLTGAIKRGVPTDRKCMGEQH 1860 AEPIQREETKKCLQTQNGTICTVNSKLLPLKSEDSVNGEVLTGAIKRGVPTDRKCMGEQH Sbjct: 1801 AEPIQREETKKCLQTQNGTICTVNSKLLPLKSEDSVNGEVLTGAIKRGVPTDRKCMGEQH 1860 Query: 1861 NSGKGEKAEFNKDLQATVLELQKSPHGGEAQKANLTDMESGSSNAMNMNVQHEREDKNIQ 1920 NSGKGEKAEFNKDLQATVLELQKSPHGGEAQKANLTDMESGSSNAMNMNVQHEREDKNIQ Sbjct: 1861 NSGKGEKAEFNKDLQATVLELQKSPHGGEAQKANLTDMESGSSNAMNMNVQHEREDKNIQ 1920 Query: 1921 KMLTESVPCYSQHLRFSTHQMKDPDPCKSGSEPKSPEGRSWNLSHIVQKTKQETHFRETV 1980 KMLTESVPCYSQHLRFSTHQMKDPDPCKSGSEPKSPEGRSWNLSHIVQKTKQETHFRETV Sbjct: 1921 KMLTESVPCYSQHLRFSTHQMKDPDPCKSGSEPKSPEGRSWNLSHIVQKTKQETHFRETV 1980 Query: 1981 LEPISGYMMKQSPHMQEGIKCMEGLKTSFPKTGKSKIGSIPRDTPWDENPRRKWDSSISQ 2040 LEPISGYMMKQSPHMQEGIKCMEGLKTSFPKTGKSKIGSIPRDTPWDENPRRKWDSSIS+ Sbjct: 1981 LEPISGYMMKQSPHMQEGIKCMEGLKTSFPKTGKSKIGSIPRDTPWDENPRRKWDSSISE 2040 Query: 2041 KTAWNQKNLQTVLKPLDFSSLMSSEYESRSYTLEFIGKKSMSPKCVTLKAKQLRILQLFN 2100 KTAWNQKNLQTVLKPLDFSSLMSSEYESRSYTLEFIGKKSMSPKCVTLKAKQLRILQLFN Sbjct: 2041 KTAWNQKNLQTVLKPLDFSSLMSSEYESRSYTLEFIGKKSMSPKCVTLKAKQLRILQLFN 2100 Query: 2101 IIRYSTENHRKKKQHRFKYKMKGKQWYTSIGEALLSATEYAKSTTSKSMIDKLLYNTAAR 2160 IIRYSTENHRKKKQHRFKYKMKGKQWYTSIGEALLSATEYAKSTTSKSMIDKLLYNTAAR Sbjct: 2101 IIRYSTENHRKKKQHRFKYKMKGKQWYTSIGEALLSATEYAKSTTSKSMIDKLLYNTAAR 2160 Query: 2161 CILSNRTRRQNLDGHITEEKEEVQENVAAIFLGLLDFFMPVLSDSKNQRNTAQLSEKEII 2220 CILSNRTRRQNLDGHITEEKEEVQENVAAIFLGLLDFFMPVLSDSKNQRNTAQLSEKEII Sbjct: 2161 CILSNRTRRQNLDGHITEEKEEVQENVAAIFLGLLDFFMPVLSDSKNQRNTAQLSEKEII 2220 Query: 2221 FNAKCLTMKEKKSSISQIHKINRESTRKHRKKCKSYLKTVSNRKCQENHGHITEEEEEVQ 2280 FNAKCLTMKEKKSSISQIHKINRESTRKHRKKCKSYLKTVSNRKCQENHGHITEEEEEVQ Sbjct: 2221 FNAKCLTMKEKKSSISQIHKINRESTRKHRKKCKSYLKTVSNRKCQENHGHITEEEEEVQ 2280 Query: 2281 ENSPATFLGPLDFFMPVLSDSKNQINTIQLSERKIILNPKCLTMKEKKPPISQIHKISRQ 2340 ENSPATFLGPLDFFMPVLSDSKNQINTIQLSERKIILNPKCLTMKEKKPPISQIHKISRQ Sbjct: 2281 ENSPATFLGPLDFFMPVLSDSKNQINTIQLSERKIILNPKCLTMKEKKPPISQIHKISRQ 2340 Query: 2341 FTTKHRKKLESNLKTKLKAMWQGENVADTFPNTTSFTPDSSDIKRQSGFQTEIDMRISGL 2400 FTTKHRKKLESNLKTKLKAMWQGENVADTFPNTTSFTPDSSDIKRQSGFQTEIDMRISGL Sbjct: 2341 FTTKHRKKLESNLKTKLKAMWQGENVADTFPNTTSFTPDSSDIKRQSGFQTEIDMRISGL 2400 Query: 2401 SHTQPTQIESLAEGIARYSDPIDKRRTSNLVKGAKLHDRESGEEKQEHLTEMDPFYAENF 2460 SHTQPTQIESLAEGIARYSDPIDKRRTSNLVKGAKLHDRESGEEKQEHLTEMDPFYAENF Sbjct: 2401 SHTQPTQIESLAEGIARYSDPIDKRRTSNLVKGAKLHDRESGEEKQEHLTEMDPFYAENF 2460 Query: 2461 MANTYLRKDRHLGKSEDVLLGETFFSKSQIYKGNSEKNVKIEKNKNGKESLKVGLARMEK 2520 MANTYLRKDRHLGKSEDVLLGETFFSKSQIYKGNSEKNVKIEKNKNGKESLKVGLARMEK Sbjct: 2461 MANTYLRKDRHLGKSEDVLLGETFFSKSQIYKGNSEKNVKIEKNKNGKESLKVGLARMEK 2520 Query: 2521 SDNCAELSEATDDAISNKYDKQNIGHSVLKENAFCNLAAIVPDSVGRHSPASEEMKRQNG 2580 SDNCAELSEATDDAISNKYDKQNIGHSVLKENAFCNLAAIVPDSVGRHSPASEEMKRQNG Sbjct: 2521 SDNCAELSEATDDAISNKYDKQNIGHSVLKENAFCNLAAIVPDSVGRHSPASEEMKRQNG 2580 Query: 2581 RLKMADRSSPQGRPLQAKQSAVSQSPDTAGYAVVSNNKEQKQNFKAQKTEAEVDLIDQEA 2640 RLKMADRSSPQGRPLQAKQSAVSQSPDTAGYAVVSNNKEQKQNFKAQKTEAEVDLIDQEA Sbjct: 2581 RLKMADRSSPQGRPLQAKQSAVSQSPDTAGYAVVSNNKEQKQNFKAQKTEAEVDLIDQEA 2640 Query: 2641 KINVAEEFNPESVFFSKIHPLQIENKKEFKTADWKTRADPKTFALPKKQQELCVSGTIWS 2700 KINVAEEFNPESVFFSKIHPLQIENKKEFKTADWKTRADPKTFALPKKQQELCVSGTIWS Sbjct: 2641 KINVAEEFNPESVFFSKIHPLQIENKKEFKTADWKTRADPKTFALPKKQQELCVSGTIWS 2700 Query: 2701 YPNPYTSISPKIIRHKDKAKTADVESTMHTKQIKLKAKRIPVSQLLEYGTASNKKELRGN 2760 YPNPYTSISPKIIRHKDKAKTADVESTMHTKQIKLKAKRI VSQLLEYGTASNKKELRGN Sbjct: 2701 YPNPYTSISPKIIRHKDKAKTADVESTMHTKQIKLKAKRITVSQLLEYGTASNKKELRGN 2760 Query: 2761 IQQQKSFQLSKNAVHRVLKAVYDSGYCVSSIKKLTEVKMEKDKPKDRTCILPQPKLEKPL 2820 IQQQKSFQLSKNAVHRVLKAVYDSGYCVSSIKKLTEVKMEKDKPKDRTCILPQPKLEKPL Sbjct: 2761 IQQQKSFQLSKNAVHRVLKAVYDSGYCVSSIKKLTEVKMEKDKPKDRTCILPQPKLEKPL 2820 Query: 2821 KEMQRSLSGCTDMSSILRKQEQDIREKEQKHQSISEDISQYYIGPLRISSQQINYSSFDA 2880 KEMQRSLSGCTDMSSILRKQEQDIREKEQKHQSISEDISQYYIGPLRISSQQINYSSFDA Sbjct: 2821 KEMQRSLSGCTDMSSILRKQEQDIREKEQKHQSISEDISQYYIGPLRISSQQINYSSFDA 2880 Query: 2881 PRIRTDEELEFLIAQRAKEKDVGIAKHSVSIPWEREGSKRLDIPLNSKGQNIFFTELDTS 2940 PRIRTDEELEFLIAQRAKEKDVGIAKHSVSIPWEREGSKRLDIPLNSKGQNIFFTELDTS Sbjct: 2881 PRIRTDEELEFLIAQRAKEKDVGIAKHSVSIPWEREGSKRLDIPLNSKGQNIFFTELDTS 2940 Query: 2941 QQKICQEQELLKQEDISMTNLGSMACPIMEPLHLENTGKVTEEEDVYINRKISSHVLGKE 3000 QQKICQEQELLKQEDISMTNLGSMACPIMEPLHLENTGKVTEEEDVYINRKISSHVLGKE Sbjct: 2941 QQKICQEQELLKQEDISMTNLGSMACPIMEPLHLENTGKVTEEEDVYINRKISSHVLGKE 3000 Query: 3001 GLKETDIFVGSKGQKFLCTNSEVQHKVPAEQKEQVNPDHVPESILDSESFLSKDPLHLKQ 3060 GLKETDIFVGSKGQKFLCTNSEVQHKVPAEQKEQVNPDHVPESILDSESFLSKDPLHLKQ Sbjct: 3001 GLKETDIFVGSKGQKFLCTNSEVQHKVPAEQKEQVNPDHVPESILDSESFLSKDPLHLKQ 3060 Query: 3061 AVNTARKENVTISESFNENLWGKEQSKLDITLKSNRQKMDFSKKLRMKHLSNYYQNKENI 3120 AVNTARKENVTISESFNENLWGKEQSKLDITLKSNRQKMDFSKKLRMKHLSNYYQNKENI Sbjct: 3061 AVNTARKENVTISESFNENLWGKEQSKLDITLKSNRQKMDFSKKLRMKHLSNYYQNKENI 3120 Query: 3121 LESVLPCILHQLYIENPKKEGSAEEIMSSKVLSPMVEKASHEVGIPVDQPPCSEGIHLNI 3180 LESVLPCILHQLYIENPKKEGSAEEIMSSKVLSPMVEKASHEVGIPVDQPPCSEGIHLNI Sbjct: 3121 LESVLPCILHQLYIENPKKEGSAEEIMSSKVLSPMVEKASHEVGIPVDQPPCSEGIHLNI 3180 Query: 3181 KGRKEHPQESTHEAFPASVSHSLMDVLQIKSPKVKKALKAINSLGYLTSNTKGIGLLFPR 3240 KGRKEHPQESTHEAFPASVSHSLMDVLQIKSPKVKKALKAINSLGYLTSNTKGIGLLFPR Sbjct: 3181 KGRKEHPQESTHEAFPASVSHSLMDVLQIKSPKVKKALKAINSLGYLTSNTKGIGLLFPR 3240 Query: 3241 QAEKEEKYTYKALPKPASHSKTDLFQFNASMQQEKLDAMDIPHYDYLTSQTREAVKQMDV 3300 QAEKEEKYTYKALPKPASHSKTDLFQFNASMQQEKLDAMDIPHYDYLTSQTREAVKQMDV Sbjct: 3241 QAEKEEKYTYKALPKPASHSKTDLFQFNASMQQEKLDAMDIPHYDYLTSQTREAVKQMDV 3300 Query: 3301 IVGYTQNSKKRQDLLKTGQKWQYLPISYENFWEHISCPQKYPCLLQHLMPQEKEALSEGG 3360 IVGYTQNSKKRQDLLKTGQKWQYLPISYENFWEHISCPQKYPCLLQHLMPQEKEALSEGG Sbjct: 3301 IVGYTQNSKKRQDLLKTGQKWQYLPISYENFWEHISCPQKYPCLLQHLMPQEKEALSEGG 3360 Query: 3361 NLSSRTPGLDLFSADQLSTITKNRLEWIVPLISPRQMKKQDSMLPLGSYHKTIKYASLLF 3420 NLSSRTPGLDLFSADQLSTITKNRLEWIVPLISPRQMKKQDSMLPLGSYHKTIKYASLLF Sbjct: 3361 NLSSRTPGLDLFSADQLSTITKNRLEWIVPLISPRQMKKQDSMLPLGSYHKTIKYASLLF 3420 Query: 3421 PKGMKSSDGVQVFDLISNNSSPKLRLGKKIETQKANEKVQKEVCLPITLHSLSASMPILQ 3480 PKGMKSSDGVQVFDLISNNSSPKLRLGKKIETQKANEKVQKEVCLPITLHSLSASMPILQ Sbjct: 3421 PKGMKSSDGVQVFDLISNNSSPKLRLGKKIETQKANEKVQKEVCLPITLHSLSASMPILQ 3480 Query: 3481 ESKGQKDSVEQVIRKGVICHKRRTSKWKKSVFSHILNTSDCGASSNRLEMQWNMTDKMVN 3540 ESKGQKDSVEQVIRKGVICHKRRTSKWKKSVFSHILNTSDCGASSNRLEMQWNMTDKMVN Sbjct: 3481 ESKGQKDSVEQVIRKGVICHKRRTSKWKKSVFSHILNTSDCGASSNRLEMQWNMTDKMVN 3540 Query: 3541 VKHRMSEIDLVAAKICESILSLPHFKLNKETIDGVISSNVKSTKQHISQGKNDRVKAMDM 3600 VKHRMSEIDLVAAKICESILSLPHFKLNKETIDGVISSNVKSTKQHISQGKNDRVKAMDM Sbjct: 3541 VKHRMSEIDLVAAKICESILSLPHFKLNKETIDGVISSNVKSTKQHISQGKNDRVKAMDM 3600 Query: 3601 KRIKSPNIILKPRKSSLSHILSIKEFPLLLDIIKQEGKMQEGKGKSSMKLTNLCTSLPSL 3660 KRIKSPNIILKPRKSSLSHILSIKEFPLLLDIIKQEGKMQEGKGKSSMKLTNLCTSLPSL Sbjct: 3601 KRIKSPNIILKPRKSSLSHILSIKEFPLLLDIIKQEGKMQEGKGKSSMKLTNLCTSLPSL 3660 Query: 3661 SHSNSNSRTKAGKDKSGTLKGCLPPLKLQASSNARRVSSAESINRDSLSNVIESKCFPQK 3720 SHSNSNSRTKAGKDKSGTLKGCLPPLKLQASSNARRVSSAESINRDSLSNVIESKCFPQK Sbjct: 3661 SHSNSNSRTKAGKDKSGTLKGCLPPLKLQASSNARRVSSAESINRDSLSNVIESKCFPQK 3720 Query: 3721 KKEDRENIVDVKDIMGLKCITLKGKKSLFRHLLHGKEPQRSNKKLEKMTQEDESNLNVVQ 3780 KKEDRENIVDVKDIMGLKCITLKGKKSLFRHLLHGKEPQRSNKKLEKMTQEDESNLNVVQ Sbjct: 3721 KKEDRENIVDVKDIMGLKCITLKGKKSLFRHLLHGKEPQRSNKKLEKMTQEDESNLNVVQ 3780 Query: 3781 NKLCASILSPPHLEWNPRIKEVYMRGITRFCLSSSTQQELSDTMEKCEQPIDDSLSSIEK 3840 NKLCASILSPPHLEWNPRIKEVYMRGITRFCLSSSTQQELSDTMEKCEQPIDDSLSSIEK Sbjct: 3781 NKLCASILSPPHLEWNPRIKEVYMRGITRFCLSSSTQQELSDTMEKCEQPIDDSLSSIEK 3840 Query: 3841 AKHMPQKDKDRVEKALEKIMHSKRIALEVKQPSIFQELELNIKEKGGKIQEDKEVEIWSK 3900 AKHMPQKDKDRVEKALEKIMHSKRIALEVKQPSIFQELELNIKEKGGKIQEDKEVEIWSK Sbjct: 3841 AKHMPQKDKDRVEKALEKIMHSKRIALEVKQPSIFQELELNIKEKGGKIQEDKEVEIWSK 3900 Query: 3901 PFASISFLPYSKVGTIEGEEAMRIKMRSSFSQPNLQESSDTEKTAYEKCISDNISNSVKK 3960 PFASISFLPYSKVGTIEGEEAMRIKMRSSFSQPNLQESSDTEKTAYEKCISDNISNSVKK Sbjct: 3901 PFASISFLPYSKVGTIEGEEAMRIKMRSSFSQPNLQESSDTEKTAYEKCISDNISNSVKK 3960 Query: 3961 ALESILQKEQRQKMEKIRALKKMKSSISQGIQLDIKEQEKRIEHIKGEPSVLLTNACASI 4020 ALESILQKEQRQKMEKIRALKKMKSSISQGIQLDIKEQEKRIEHIKGEPSVLLTNACASI Sbjct: 3961 ALESILQKEQRQKMEKIRALKKMKSSISQGIQLDIKEQEKRIEHIKGEPSVLLTNACASI 4020 Query: 4021 PSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEAGEKADGVASKGDITIKVQKAKDY 4080 PSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEAGEKADGVASKGDITIKVQKAKDY Sbjct: 4021 PSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEAGEKADGVASKGDITIKVQKAKDY 4080 Query: 4081 MQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPLNTKEPGKMDQEAQEQGKEDREGE 4140 MQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPLNTKEPGKMDQEAQEQGKEDREGE Sbjct: 4081 MQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPLNTKEPGKMDQEAQEQGKEDREGE 4140 Query: 4141 EQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADGVGIEQGKMDGDKNEQERVLFLYL 4200 EQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADGVGIEQGKMDGDKNEQERVLFLYL Sbjct: 4141 EQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADGVGIEQGKMDGDKNEQERVLFLYL 4200 Query: 4201 PSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSSETGKKANGVPSEGDSASEVQKA 4260 PSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSSETGKKANGVPSEGDSASEVQKA Sbjct: 4201 PSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSSETGKKANGVPSEGDSASEVQKA 4260 Query: 4261 KDYMQQKEEDESKQETVLFLHLPSESSLTCYELNTRKEGEEDLQGIIKSATLQLRQQKSF 4320 KDYMQQKEEDESKQETVLFLHLPSESSLTCYELNTRKEGEEDLQGIIKSATLQLRQQKSF Sbjct: 4261 KDYMQQKEEDESKQETVLFLHLPSESSLTCYELNTRKEGEEDLQGIIKSATLQLRQQKSF 4320 Query: 4321 DAGKIAHTKSFGVDSSNDVKTVQEYKPQKEVDRGKTVSVDYIMQPEGTIFEAEQLSLPHT 4380 DAGKIAHTKSFGVDSSNDVKTVQEYKPQKEVDRGKTVSVDYIMQPEGTIFEAEQLSLPHT Sbjct: 4321 DAGKIAHTKSFGVDSSNDVKTVQEYKPQKEVDRGKTVSVDYIMQPEGTIFEAEQLSLPHT 4380 Query: 4381 LNIPGSSGSKTREVLTNIKEKLRHVQERKSELDVFLTIPSLSHCKLDKRTAGKKEEQGVT 4440 LNIPGSSGSKTREVLTNIKEKLRHVQERKSELDVFLTIPSLSHCKLDKRTAGKKEEQGVT Sbjct: 4381 LNIPGSSGSKTREVLTNIKEKLRHVQERKSELDVFLTIPSLSHCKLDKRTAGKKEEQGVT 4440 Query: 4441 RSFLPPSWHMESSDTGKLKYTLSYLNDITGDSNRTKYMAQIQKDKANISEKSVMHPEYIA 4500 RSFLPPSWHMESSDTGKLKYTLSYLNDITGDSNRTKYMAQIQKDKANISEKSVMHPEYIA Sbjct: 4441 RSFLPPSWHMESSDTGKLKYTLSYLNDITGDSNRTKYMAQIQKDKANISEKSVMHPEYIA 4500 Query: 4501 VKAEKSPLSHILKTKELQVNISQQGEKAQEGEVEIVVLLSKTCPFVTSSAFLELDSIKEE 4560 VKAEKSPLSHILKTKELQVNISQQGEKAQEGEVEIVVLLSKTCPFVTSSAFLELDSIKEE Sbjct: 4501 VKAEKSPLSHILKTKELQVNISQQGEKAQEGEVEIVVLLSKTCPFVTSSAFLELDSIKEE 4560 Query: 4561 EGEPRITRSFMPHLEIQESLPSRQTAPTKPTESLVKKEKQLLPQKEDRVQTVSMHGLMHP 4620 EGEPRITRSFMPHLEIQESLPSRQTAPTKPTESLVKKEKQLLPQKEDRVQTVSMHGLMHP Sbjct: 4561 EGEPRITRSFMPHLEIQESLPSRQTAPTKPTESLVKKEKQLLPQKEDRVQTVSMHGLMHP 4620 Query: 4621 NGAVFKAKTSAPPQVFSITEHSPLSKRKEPQWGMKERAGQKQDRTGRPHVILTKTHPFMP 4680 NGAVFKAKTSAPPQVFSITEHSPLSKRKEPQWGMKERAGQKQDRTGRPHVILTKTHPFMP Sbjct: 4621 NGAVFKAKTSAPPQVFSITEHSPLSKRKEPQWGMKERAGQKQDRTGRPHVILTKTHPFMP 4680 Query: 4681 SLSHHRFSPSQPKLPISSGAGKSRLANSNEGISSHKVILKANQQMPYKEAKDRVKIEGRE 4740 SLSHHRFSPSQPKLPISSGAGKSRLANSNEGISSHKVILKANQQMPYKEAKDRVKIEGRE Sbjct: 4681 SLSHHRFSPSQPKLPISSGAGKSRLANSNEGISSHKVILKANQQMPYKEAKDRVKIEGRE 4740 Query: 4741 GRILPKRIHLRAEALPLALLCNGKNYSLHIEEQGEGVQESKKEPGVVPRKPASFPPPPFY 4800 GRILPKRIHLRAEALPLALLCNGKNYSLHIEEQGEGVQESKKEPGVVPRKPASFPPPPFY Sbjct: 4741 GRILPKRIHLRAEALPLALLCNGKNYSLHIEEQGEGVQESKKEPGVVPRKPASFPPPPFY 4800 Query: 4801 LNCDTRRNEKEGTLGKTQFSFPPLKIQDSSDSGKKAYTESLHGYTLSNSKGPVQPTAQGE 4860 LNCDTRRNEKEGTLGKTQFSFPPLKIQDSSDSGKKAYTESLHGYTLSNSKGPVQPTAQGE Sbjct: 4801 LNCDTRRNEKEGTLGKTQFSFPPLKIQDSSDSGKKAYTESLHGYTLSNSKGPVQPTAQGE 4860 Query: 4861 EKGGLRIDMEDKMLPKCTDLKAKQLLLSDILNTKKLQWKSKEQKRKIQEDKNKQVKGLPS 4920 EKGGLRIDMEDKMLPKCTDLKAKQLLLSDILNTKKLQWKSKEQKRKIQEDKNKQVKGLPS Sbjct: 4861 EKGGLRIDMEDKMLPKCTDLKAKQLLLSDILNTKKLQWKSKEQKRKIQEDKNKQVKGLPS 4920 Query: 4921 INTSLLTPPYLKFDTTEGQENVIRIAKVSLPQSRSKESSDAGRIACPEATHGELSSDVKQ 4980 INTSLLTPPYLKFDTTEGQENVIRIAKVSLPQSRSKESSDAGRIACPEATHGELSSDVKQ Sbjct: 4921 INTSLLTPPYLKFDTTEGQENVIRIAKVSLPQSRSKESSDAGRIACPEATHGELSSDVKQ 4980 Query: 4981 LKAHLLQKEEKDREKVADMTSVLDPNKMYLKAKKSPVLHTHSFSDLQWKTREQEEEKVQK 5040 LKAHLLQKEEKDREKVADMTSVLDPNKMYLKAKKSPVLHTHSFSDLQWKTREQEEEKVQK Sbjct: 4981 LKAHLLQKEEKDREKVADMTSVLDPNKMYLKAKKSPVLHTHSFSDLQWKTREQEEEKVQK 5040 Query: 5041 VKSGPGVMLSKSPSRSSPLHLNVNTGFQEESIPILTRPSFPLVKLQVSPDTEGGTCIRPI 5100 VKSGPGVMLSKSPSRSSPLHLNVNTGFQEESIPILTRPSFPLVKLQVSPDTEGGTCIRPI Sbjct: 5041 VKSGPGVMLSKSPSRSSPLHLNVNTGFQEESIPILTRPSFPLVKLQVSPDTEGGTCIRPI 5100 Query: 5101 AGDILIYLQKGKHVSQNKEEDDVQIVSILIFPKHQEEKVQECEGEPGVVLTKSTSLPSLS 5160 AGDILIYLQKGKHVSQNKEEDDVQIVSILIFPKHQEEKVQECEGEPGVVLTKSTSLPSLS Sbjct: 5101 AGDILIYLQKGKHVSQNKEEDDVQIVSILIFPKHQEEKVQECEGEPGVVLTKSTSLPSLS 5160 Query: 5161 QLELDKETHLGNEMLRLKRPILRRISHIGETVHRESVVGDIPKDVKNEKQHIPQKEERNQ 5220 QLELDKETHLGNEMLRLKRPILRRISHIGETVHRESVVGDIPKDVKNEKQHIPQKEERNQ Sbjct: 5161 QLELDKETHLGNEMLRLKRPILRRISHIGETVHRESVVGDIPKDVKNEKQHIPQKEERNQ 5220 Query: 5221 KKIIDMRGTDITLKSKKSPRSCMLHRTELHVNIGGQGRKEHEGQDKPPGMIQRKMCILFS 5280 KKIIDMRGTDITLKSKKSPRSCMLHRTELHVNIGGQGRKEHEGQDKPPGMIQRKMCILFS Sbjct: 5221 KKIIDMRGTDITLKSKKSPRSCMLHRTELHVNIGGQGRKEHEGQDKPPGMIQRKMCILFS 5280 Query: 5281 KPLPSNLKLERATHADEERLGGKTSFVLPLMPSALPDTEKTADAEARSGDVRKGKPHRSQ 5340 KPLPSNLKLERATHADEERLGGKTSFVLPLMPSALPDTEKTADAEARSGDVRKGKPHRSQ Sbjct: 5281 KPLPSNLKLERATHADEERLGGKTSFVLPLMPSALPDTEKTADAEARSGDVRKGKPHRSQ 5340 Query: 5341 KENRHEVKTIDMRFRIHCQEARISPMSHILNAKELVLNINKLEKKVHKDKDEACVVLSRT 5400 KENRHEVKTIDMRFRIHCQEARISPMSHILNAKELVLNINKLEKKVHKDKDEACVVLSRT Sbjct: 5341 KENRHEVKTIDMRFRIHCQEARISPMSHILNAKELVLNINKLEKKVHKDKDEACVVLSRT 5400 Query: 5401 FLSIPSAPPLYLDSGNKTDKDTPGITGSSCPQRTLHVPSNTQKITNRDSVEGVDKNVVKQ 5460 FLSIPSAPPLYLDSGNKTDKDTPGITGSSCPQRTLHVPSNTQKITNRDSVEGVDKNVVKQ Sbjct: 5401 FLSIPSAPPLYLDSGNKTDKDTPGITGSSCPQRTLHVPSNTQKITNRDSVEGVDKNVVKQ 5460 Query: 5461 AEQYVPRPEAEQQLTSNFMISVQQRNQPSRVTSEEDLNQLVLNSRDEDIYFTGFGTIRSG 5520 AEQYVPRPEAEQQLTSNFMISVQQRNQPSRVTSEEDLNQLVLNSRDEDIYFTGFGTIRSG Sbjct: 5461 AEQYVPRPEAEQQLTSNFMISVQQRNQPSRVTSEEDLNQLVLNSRDEDIYFTGFGTIRSG 5520 Query: 5521 KRPEWLFTGKKAQPVKYKTETLTAFLSYPTMDATKMGGLEEDTEIMDNLNHKISPKASVS 5580 KRPEWLFTGKKAQPVKYKTETLTAFLSYPTMDATKMGGLEEDTEIMDNLNHKISPKASVS Sbjct: 5521 KRPEWLFTGKKAQPVKYKTETLTAFLSYPTMDATKMGGLEEDTEIMDNLNHKISPKASVS 5580 Query: 5581 LIRKISKELYVTLGTPASSKGFSVSERYAHQQETSSKVSPELAGSCKFDKPKEDGQSNDR 5640 LIRKISKELYVTLGTPASSKGFSVSERYAHQQETSSKVSPELAGSCKFDKPKEDGQSNDR Sbjct: 5581 LIRKISKELYVTLGTPASSKGFSVSERYAHQQETSSKVSPELAGSCKFDKPKEDGQSNDR 5640 Query: 5641 ISKMFSPKVLAPQTKGSLKKISIVTNWNAPQNIEEQDIVMKKQVIRRCEHGHKTRTNTIL 5700 ISKMFSPKVLAPQTKGSLKKISIVTNWNAPQNIEEQDIVMKKQVIRRCEHGHKTRTNTIL Sbjct: 5641 ISKMFSPKVLAPQTKGSLKKISIVTNWNAPQNIEEQDIVMKKQVIRRCEHGHKTRTNTIL 5700 Query: 5701 SKFPLQSGKQKTPSETDVDKKTTAHLSLQMLPGIHMDMTEIDPAKGGRKQALLISEQEEG 5760 SKFPLQSGKQKTPSETDVDKKTTAHLSLQMLPGIHMDMTEIDPAKGGRKQALLISEQEEG Sbjct: 5701 SKFPLQSGKQKTPSETDVDKKTTAHLSLQMLPGIHMDMTEIDPAKGGRKQALLISEQEEG 5760 Query: 5761 VLELLPKSLFPPWTFQFQSGDLEEKHQTDANTNINLEQKKLEMDNDSTVNQKEGKLKIGT 5820 VLE LPKSLFPPWTFQFQSGDLEEKHQTDANTNINLEQKKLEMDNDSTVNQKEGKLKIGT Sbjct: 5761 VLEFLPKSLFPPWTFQFQSGDLEEKHQTDANTNINLEQKKLEMDNDSTVNQKEGKLKIGT 5820 Query: 5821 NRALHLQEEKTEMHKARTANLEKERGRMDTSSSAHPHLPSLKAEESQMKTQVITHRENSR 5880 NRALHLQEEKTEMHKARTANLEKERGRMDTSSSAHPHL SLKAEESQMKTQVITHRENSR Sbjct: 5821 NRALHLQEEKTEMHKARTANLEKERGRMDTSSSAHPHLLSLKAEESQMKTQVITHRENSR 5880 Query: 5881 LIMQKQKKELEASNAKQSIQLQKLFQRNVLDSFYSYVPLSPKCKDQKGRLTIRDLKRELS 5940 LIMQKQKKELEASNAKQSIQLQKLFQRNVLDSFYSYVPLSPK KDQKGRLTIRDLKRELS Sbjct: 5881 LIMQKQKKELEASNAKQSIQLQKLFQRNVLDSFYSYVPLSPKRKDQKGRLTIRDLKRELS 5940 Query: 5941 TKYLTMKIQNHPIPQMLNITGRGTPSNRKKLEYDVKLKNIASWSKDVSGIFIRSLSISIM 6000 TKYLTMKIQNHPIPQMLNITGRGTPSNRKKLEYDVKLKNIASWSKDVSGIFIRSLSISIM Sbjct: 5941 TKYLTMKIQNHPIPQMLNITGRGTPSNRKKLEYDVKLKNIASWSKDVSGIFIRSLSISIM 6000 Query: 6001 RSPHTDPKTNLEREKRICLPKFQEKSPNTSEMSKRDTLTIVKGEQNFTNTVPQDPQPFAV 6060 RSPHTDPKTNLEREKRICLPKFQEKSPNTSEMSKRDTLTIVKGEQNFTNTVPQDPQPFAV Sbjct: 6001 RSPHTDPKTNLEREKRICLPKFQEKSPNTSEMSKRDTLTIVKGEQNFTNTVPQDPQPFAV 6060 Query: 6061 DKQQMQKLPNVKSEANLRSEMNKKYLKAQTKERIVPEHDVSRIIKKPDLRIIEQEEKILK 6120 DKQQMQKLPNVKSEANLRSEMNKKYLKAQTKERIVPEHDVSRIIKKPDLRIIEQEEKILK Sbjct: 6061 DKQQMQKLPNVKSEANLRSEMNKKYLKAQTKERIVPEHDVSRIIKKPDLRIIEQEEKILK 6120 Query: 6121 RILTPTECPSMLEDPKLPKQRDQSEPVWDMTTQKVQQQKAFPGTVPIPPQVKSSEVKIVA 6180 RILTPTECPSMLEDPKLPKQRDQSEPVWDMTTQKVQQQKAFPGTVPIPPQVKSSEVKIVA Sbjct: 6121 RILTPTECPSMLEDPKLPKQRDQSEPVWDMTTQKVQQQKAFPGTVPIPPQVKSSEVKIVA 6180 Query: 6181 DSTNAEHLLPICEATKAISESQVKNMIQDKVSSDKLDNIQAYKPDDLKSPPFPEGPDTIS 6240 DSTNAEHLLPICEATKAISESQVKNMIQDKVSSDKLDNIQAYKPDDLKSPPFPEGPDTIS Sbjct: 6181 DSTNAEHLLPICEATKAISESQVKNMIQDKVSSDKLDNIQAYKPDDLKSPPFPEGPDTIS 6240 Query: 6241 TAIYPKTQHKSLLEQFTPKEKNKLTSHLESKALEIQLNLIPEMARKSLQMFNFYPKGTIS 6300 TAIYPKTQHKSLLEQFTPKEKNKLTSHLESKALEIQLNLIPEMARKSLQMFNFYPKGTIS Sbjct: 6241 TAIYPKTQHKSLLEQFTPKEKNKLTSHLESKALEIQLNLIPEMARKSLQMFNFYPKGTIS 6300 Query: 6301 KDNSWRFYSRHKTMNFMSLEGTDTIEPNSKHKHQKDSPLASNMKTLIVDVSSDSEETITK 6360 KDNSWRFYSRHKTMNFMSLEGTDTIEPNSKHKHQKDSPLASNMKTLIVDVSSDSEETITK Sbjct: 6301 KDNSWRFYSRHKTMNFMSLEGTDTIEPNSKHKHQKDSPLASNMKTLIVDVSSDSEETITK 6360 Query: 6361 LQSINKLENGTSAVTSASEMLLPHTLQNHSVKEKGKLLMHFSVKTLEIQMKAFPRIVRES 6420 LQSINKLENGTSAVTSASEMLLPHTLQNHSVKEKGKLLMHFSVKTLEIQMKAFPRIVRES Sbjct: 6361 LQSINKLENGTSAVTSASEMLLPHTLQNHSVKEKGKLLMHFSVKTLEIQMKAFPRIVRES 6420 Query: 6421 YAMTSAHERKKPLSNCIHPGFTGPKRQNRILLLSEEKSLHQIDLDLQYKYLRFLLGLPVG 6480 YAMTSAHERKKPLSNCIHPGFTGPKRQNRILLLSEEKSLHQIDLDLQYKYLRFLLGLPVG Sbjct: 6421 YAMTSAHERKKPLSNCIHPGFTGPKRQNRILLLSEEKSLHQIDLDLQYKYLRFLLGLPVG 6480 Query: 6481 STFPKPNVLPKHSKLNTIAVCKNVNAGGQSGSLSIDTELLEQHISFKKQSPHENSSLIRK 6540 STFPKPNVLPKHSKLNTIAVCKNVNAGGQSGSLSIDTELLEQHISFKKQSPHENSSLIRK Sbjct: 6481 STFPKPNVLPKHSKLNTIAVCKNVNAGGQSGSLSIDTELLEQHISFKKQSPHENSSLIRK 6540 Query: 6541 FPQPTLVCASDRDLHSPRKKDTQVLSESEFHVTPEKNKQYHVWFQERNTCESVDLRTQRN 6600 FPQPTLVCASDRDLHSPRKKDTQVLSESEFHVTPEKNKQYHVWFQERNTCESVDLRTQRN Sbjct: 6541 FPQPTLVCASDRDLHSPRKKDTQVLSESEFHVTPEKNKQYHVWFQERNTCESVDLRTQRN 6600 Query: 6601 ATGSAVSCETQISEDFVDIQTDIESPADLDECSCLEVSESEECVFLEANSYLSQESENIL 6660 ATGSAVSCETQISEDFVDIQTDIESPADLDECSCLEVSESEECVFLEANSYLSQESENIL Sbjct: 6601 ATGSAVSCETQISEDFVDIQTDIESPADLDECSCLEVSESEECVFLEANSYLSQESENIL 6660 Query: 6661 FELQTGIPLENVYKITTDLKSFYSEDSGSHCTRECRKETLIITPPSCKSHKSRKYRSSSK 6720 FELQTGIPLENVYKITTDLKSFYSEDSGSHCTRECRKETLIITPPSCKSHKSRKYRSSSK Sbjct: 6661 FELQTGIPLENVYKITTDLKSFYSEDSGSHCTRECRKETLIITPPSCKSHKSRKYRSSSK 6720 Query: 6721 MKSPDWLCHSSSNTAEIQSRSSSVSFSEEKISWTTKSRTSYSSAPLTESNIKSHLAKNQG 6780 MKSPDWLCHSSSNTAEIQSRSSSVSFSEEKISWTTKSRTSYSSAPLTESNIKSHLAKNQG Sbjct: 6721 MKSPDWLCHSSSNTAEIQSRSSSVSFSEEKISWTTKSRTSYSSAPLTESNIKSHLAKNQG 6780 Query: 6781 KSHRHPESQERKKARSDLFRKNSSHWDHDYSCTHSKGKRDRKKRVYDYESERLDCFQSKH 6840 KSHRHPESQERKKARSDLFRKNSSHWDHDYSCTHSKGKRDRKKRVYDYESERLDCFQSKH Sbjct: 6781 KSHRHPESQERKKARSDLFRKNSSHWDHDYSCTHSKGKRDRKKRVYDYESERLDCFQSKH 6840 Query: 6841 KSASKPHHDDINFYSERKQNRPFFFACVPADSLEVIPKTIRWTIPPETLRKRNFRIPLVA 6900 KSASKPHHDDINFYSERKQNRPFFFACVPADSLEVIPKTIRWTIPPETLRKRNFRIPLVA Sbjct: 6841 KSASKPHHDDINFYSERKQNRPFFFACVPADSLEVIPKTIRWTIPPETLRKRNFRIPLVA 6900 Query: 6901 KISSSWNIWSSSKKLLGSLSGSLTTVFHS 6929 KISSSWNIWSSSKKLLGSLSGSLTTVFHS Sbjct: 6901 KISSSWNIWSSSKKLLGSLSGSLTTVFHS 6929 >gi|239744870 PREDICTED: hypothetical protein LOC643677 [Homo sapiens] Length = 6929 Score = 1.372e+04 bits (35614), Expect = 0.0 Identities = 6916/6929 (99%), Positives = 6919/6929 (99%) Query: 1 MKACASFWKKPTLPEKGSSDVQELQRIGQLLIHLQEKEKRITSSLTSEEKECNFEDRILF 60 MKACASFWKKPTLPEKGSSDVQELQRIGQLLIHLQEKEKRITSSLTSEEKECNFEDRILF Sbjct: 1 MKACASFWKKPTLPEKGSSDVQELQRIGQLLIHLQEKEKRITSSLTSEEKECNFEDRILF 60 Query: 61 SREILWSGTSESEDQVSPSSESHVPSSNGISSSLPLFYSEVEETCLSHTEHPDREYETIQ 120 SREILWSGTSESEDQVSPSSESHVPSSNGISSSLPLFYSEVEETCLSHTEHPDREYETIQ Sbjct: 61 SREILWSGTSESEDQVSPSSESHVPSSNGISSSLPLFYSEVEETCLSHTEHPDREYETIQ 120 Query: 121 FSSKKLFSMMKTNKNKNSGFSSDLSFSASRFTVENEDLDVAPCPLAHLFLSRDQVRLLEE 180 FSSKKLFSMMKTNKNKNSGFSSDLSFSASRFTVENEDLDVAPCPLAHLFLSRDQVRLLEE Sbjct: 121 FSSKKLFSMMKTNKNKNSGFSSDLSFSASRFTVENEDLDVAPCPLAHLFLSRDQVRLLEE 180 Query: 181 NVRNQIPSKPKTKLGSRTTYQCSRSQESLNQNQPSVGMVISVQAQDSFPGQNAFQNQGLY 240 NVRNQIPSKPKTKLGSRTTYQCSRSQESLNQNQPSVGMVISVQAQDSFPGQNAFQNQGLY Sbjct: 181 NVRNQIPSKPKTKLGSRTTYQCSRSQESLNQNQPSVGMVISVQAQDSFPGQNAFQNQGLY 240 Query: 241 EVQFTSQAQYINHNQESIKSQPESKASNFAQPEDVMKKPFSSSTQDSFQSQDLDRNQHFV 300 EVQFTSQAQYINHNQESIKSQPESKASNFAQPEDVMKKPFSSSTQDSFQSQDLDRNQHFV Sbjct: 241 EVQFTSQAQYINHNQESIKSQPESKASNFAQPEDVMKKPFSSSTQDSFQSQDLDRNQHFV 300 Query: 301 EVPSIVEAKYSVKGLESDEHLGEDQHCVWFIDSNKVKYSIKGQDTIFKNAEFLVLTLNPN 360 EVPSIVEAKYSVKGLESDEHLGEDQHCVWFIDSNKVKYSIKGQDTIFKNAEFLVLTLNPN Sbjct: 301 EVPSIVEAKYSVKGLESDEHLGEDQHCVWFIDSNKVKYSIKGQDTIFKNAEFLVLTLNPN 360 Query: 361 LVTEDMPQLRSVKAQGQQQIVSSELNQDSVYSSVPLLSTIKGQKNRRKTPDSKSKLSLNV 420 LVTEDMPQLRSVKAQGQQQIVSSELNQDSVYSSVPLLSTIKGQKNRRKTPDSKSKLSLNV Sbjct: 361 LVTEDMPQLRSVKAQGQQQIVSSELNQDSVYSSVPLLSTIKGQKNRRKTPDSKSKLSLNV 420 Query: 421 PSLKAKKTPTSQVFQITVCHTLKNRNELGCKNNTEKKELHERKDISDIALHLISVSKLIL 480 PSLKAKKTPTSQVFQITVCHTLKNRNELGCKNNTEKKELHERKDISDIALHLISVSKLIL Sbjct: 421 PSLKAKKTPTSQVFQITVCHTLKNRNELGCKNNTEKKELHERKDISDIALHLISVSKLIL 480 Query: 481 PYVKNYSRKQLVKVMPGLIKCGHFLQKQNKSPDTEKINYAGPLEETGISDITKKEKEYDK 540 PYVKNYSRKQLVKVMPGLIKCGHFLQKQNKSPDTEKINYAGPLEETGISDITKKEKEYDK Sbjct: 481 PYVKNYSRKQLVKVMPGLIKCGHFLQKQNKSPDTEKINYAGPLEETGISDITKKEKEYDK 540 Query: 541 ENKRLKNISPKMLPQLEQSFMVNTVQLKAPCLLVETNGKSKESLKDSITQAKGIGITEFH 600 ENKRLKNISPKMLPQLEQSFMVNTVQLKAPCLLVETNGKSKESLKDSITQAKGIGITEFH Sbjct: 541 ENKRLKNISPKMLPQLEQSFMVNTVQLKAPCLLVETNGKSKESLKDSITQAKGIGITEFH 600 Query: 601 VLNSKKPFDLHIPKHKTSLEEAISKPMQKLVSSPEMESNNRMKIQEDLQSSENSHLQLSN 660 VLNSKKPFDLHIPKHKTSLEEAISKPMQKLVSSPEMESNNRMKIQEDLQSSENSHLQLSN Sbjct: 601 VLNSKKPFDLHIPKHKTSLEEAISKPMQKLVSSPEMESNNRMKIQEDLQSSENSHLQLSN 660 Query: 661 GEELPTSTPKTQRCFPRENTQKQKDFLELVLELSNVGLLISLGSKMHKSSEELEAIKIQV 720 GEELPTSTPKTQRCFPRENTQKQKDFLELVLELSNVGLLIS GSKMHKSSEELEAIKIQV Sbjct: 661 GEELPTSTPKTQRCFPRENTQKQKDFLELVLELSNVGLLISPGSKMHKSSEELEAIKIQV 720 Query: 721 NTESVNLKESKPLILNVTEDSDLRESEELECNTGSNITNMHQDKETSDAFHSATYTTISQ 780 NTESVNLKESKPLILNVTEDSDLRESEELECNTGSNITNMHQDKETSDAFHSATYTTISQ Sbjct: 721 NTESVNLKESKPLILNVTEDSDLRESEELECNTGSNITNMHQDKETSDAFHSATYTTISQ 780 Query: 781 LPDTETHSISKAKADTLRIIRLSHSASKQEKLPDEKETQNAEYIDKSCTFKKPQQCDRKE 840 LPDTETHSISKAKADTLRIIRLSHSASKQEKLPDEKETQNAEYIDKSCTFKKPQQCDRKE Sbjct: 781 LPDTETHSISKAKADTLRIIRLSHSASKQEKLPDEKETQNAEYIDKSCTFKKPQQCDRKE 840 Query: 841 QEKEANSELTQGFRFSIHLKQKPKYVKFQMEQISSGSSKAPNKEQEVQPQTLSTQTILEN 900 QEKEANSELTQGFRFSIHLKQKPKYVKFQMEQISSGSSKAPNKEQEVQPQTLSTQTILEN Sbjct: 841 QEKEANSELTQGFRFSIHLKQKPKYVKFQMEQISSGSSKAPNKEQEVQPQTLSTQTILEN 900 Query: 901 SPCPMMDPFQVEKVKQSTDRPTDRESAGDPKNPLTMPENLPVGELLIETTEYSVPFGGNL 960 SPCPMMDPFQVEKVKQSTDRPTDRESAGDPKNPLTMPENLPVGELLIETTEYSVPFGGNL Sbjct: 901 SPCPMMDPFQVEKVKQSTDRPTDRESAGDPKNPLTMPENLPVGELLIETTEYSVPFGGNL 960 Query: 961 QKTTDSHIAEEKEDVKRYLPAVALGSFNNHLLTLPYFKRQEIKKKLSETKSVLSVKYVIM 1020 QKTTDSHIAEEKEDVKRYLPAVALGSFNNHLLTLPYFKRQEIKKKLSETKSVLSVKYVIM Sbjct: 961 QKTTDSHIAEEKEDVKRYLPAVALGSFNNHLLTLPYFKRQEIKKKLSETKSVLSVKYVIM 1020 Query: 1021 KVKKPAISLMPYINICGTSNHRKKMGGNFEIIIKQILQDKIAAGMLLNVIYPPMSILPNT 1080 KVKKPAISLMPYINICGTSNHRKKMGGNFEIIIKQILQDKIAAGMLLNVIYPPMSILPNT Sbjct: 1021 KVKKPAISLMPYINICGTSNHRKKMGGNFEIIIKQILQDKIAAGMLLNVIYPPMSILPNT 1080 Query: 1081 RMYSRLNAENHSHIKLVQEESQIEREEKYPYFINEGNESQNTLDAKLQDEVKGVKETLPK 1140 RMYSRLNAENHSHIKLVQEESQIEREEKYPYFINEGNESQNTLDAKLQDEVKGVKETLPK Sbjct: 1081 RMYSRLNAENHSHIKLVQEESQIEREEKYPYFINEGNESQNTLDAKLQDEVKGVKETLPK 1140 Query: 1141 AVLHDSCNLGLDAHLEKEIKTEKEMHQPIPFTETIIESVVSPIMELSHAENVKSTQKTQT 1200 AVLHDSCNLGLDAHLEKEIKTEKEMHQPIPFTETIIESVVSPIMELSHAENVKSTQKTQT Sbjct: 1141 AVLHDSCNLGLDAHLEKEIKTEKEMHQPIPFTETIIESVVSPIMELSHAENVKSTQKTQT 1200 Query: 1201 DCKCTADSETPSPISGKSLIGDPLNQTRESYIPSNGSDTREMGYCFAEEKTEIPKDLPAT 1260 DCKCTADSETPSPISGKSLIGDPLNQTRESYIPSNGSDTREMGYCFAEEKTEIPKDLPAT Sbjct: 1201 DCKCTADSETPSPISGKSLIGDPLNQTRESYIPSNGSDTREMGYCFAEEKTEIPKDLPAT 1260 Query: 1261 SPETFNYCTPVLSCSKVMKKRVTFALTTSTAKPKCVNTKAVKPSISETVSVTSHRKKSEL 1320 SPETFNYCTPVLSCSKVMKKRVTFALTTSTAKPKCVNTKAVKPSISETVSVTSHRKKSEL Sbjct: 1261 SPETFNYCTPVLSCSKVMKKRVTFALTTSTAKPKCVNTKAVKPSISETVSVTSHRKKSEL 1320 Query: 1321 DFKTKFKKINQTKGLVPECLNTLCSPMHSRLQREFCLPASQLKQGETADKTYTDVFAKNS 1380 DFKTKFKKINQTKGLVPECLNTLCSPMHSRLQREFCLPASQLKQGETADKTYTDVFAKNS Sbjct: 1321 DFKTKFKKINQTKGLVPECLNTLCSPMHSRLQREFCLPASQLKQGETADKTYTDVFAKNS 1380 Query: 1381 ISHDREEKLQDGKEEEHKVLLEAAPQLSQHLGSEAGQMKEIHLESDPVLNCLTLELHING 1440 ISHDREEKLQDGKEEEHKVLLEAAPQLSQHLGSEAGQMKEIHLESDPVLNCLTLELHING Sbjct: 1381 ISHDREEKLQDGKEEEHKVLLEAAPQLSQHLGSEAGQMKEIHLESDPVLNCLTLELHING 1440 Query: 1441 QRLQHQTGFEQTTLETSLQMGPLEAEELQKANETENDIKVLGGPKIPPPKALQALENSDG 1500 QRLQHQTGFEQTTLETSLQMGPLEAEELQKANETENDIKVLGGPKIPPPKALQALENSDG Sbjct: 1441 QRLQHQTGFEQTTLETSLQMGPLEAEELQKANETENDIKVLGGPKIPPPKALQALENSDG 1500 Query: 1501 LILNAYQKDNELVKSDEELNQPGSTNIQVQPQTHFTQTILKSTSCPTLDQFPFEKVESHV 1560 LILNAYQKDNELVKSDEELNQPGSTNIQVQPQTHFTQTILKSTSCPTLDQFPFEKVESHV Sbjct: 1501 LILNAYQKDNELVKSDEELNQPGSTNIQVQPQTHFTQTILKSTSCPTLDQFPFEKVESHV 1560 Query: 1561 RFSPLKSGEAKVDEIIFYAREGGISSDSSHQKEQAGGTEKKETAIFGSCMPALSTPKTTR 1620 RFSPLKSGEAKVDEIIFYAREGGISSDSSHQKEQAGGTEKKETAIFGSCMPALSTPKTTR Sbjct: 1561 RFSPLKSGEAKVDEIIFYAREGGISSDSSHQKEQAGGTEKKETAIFGSCMPALSTPKTTR 1620 Query: 1621 NLKQFSDMKTLVNPKCGIIKAKKPSISYMLNIRAGAGPKRRKELSCNLTTKMKELHQGKK 1680 NLKQFSDMKTLVNPKCGIIKAKKPSISYMLNIRAGAGPKRRKELSCNLTTKMKELHQGKK Sbjct: 1621 NLKQFSDMKTLVNPKCGIIKAKKPSISYMLNIRAGAGPKRRKELSCNLTTKMKELHQGKK 1680 Query: 1681 GVDETYAFLTMTPDINKYSKVETEKDTLREKRLSSTQVKQDTSPHEDSITSRDIKETLLQ 1740 GVDETYAFLTMTPDINKYSKVETEKDTLREKRLSSTQVKQDTSPHEDSITSRDIKETLLQ Sbjct: 1681 GVDETYAFLTMTPDINKYSKVETEKDTLREKRLSSTQVKQDTSPHEDSITSRDIKETLLQ 1740 Query: 1741 DEEQEERKQEPLLKVIPQHLQHFMFRSGQGKDLDFHKLENQGSRKILFVTKQDVPQQLQP 1800 DEEQEERKQE LLKVIPQHLQHFMFRSGQGKDLDFHKLENQGSRKILFVTKQDVPQQLQP Sbjct: 1741 DEEQEERKQEALLKVIPQHLQHFMFRSGQGKDLDFHKLENQGSRKILFVTKQDVPQQLQP 1800 Query: 1801 AEPIQREETKKCLQTQNGTICTVNSKLLPLKSEDSVNGEVLTGAIKRGVPTDRKCMGEQH 1860 AEPIQREETKKCLQTQNGTICTVNSKLLPLKSEDSVNGEVLTGAIKRGVPTDRKCMGEQH Sbjct: 1801 AEPIQREETKKCLQTQNGTICTVNSKLLPLKSEDSVNGEVLTGAIKRGVPTDRKCMGEQH 1860 Query: 1861 NSGKGEKAEFNKDLQATVLELQKSPHGGEAQKANLTDMESGSSNAMNMNVQHEREDKNIQ 1920 NSGKGEKAEFNKDLQATVLELQKSPHGGEAQKANLTDMESGSSNAMNMNVQHEREDKNIQ Sbjct: 1861 NSGKGEKAEFNKDLQATVLELQKSPHGGEAQKANLTDMESGSSNAMNMNVQHEREDKNIQ 1920 Query: 1921 KMLTESVPCYSQHLRFSTHQMKDPDPCKSGSEPKSPEGRSWNLSHIVQKTKQETHFRETV 1980 KMLTESVPCYSQHLRFSTHQMKDPDPCKSGSEPKSPEGRSWNLSHIVQKTKQETHFRETV Sbjct: 1921 KMLTESVPCYSQHLRFSTHQMKDPDPCKSGSEPKSPEGRSWNLSHIVQKTKQETHFRETV 1980 Query: 1981 LEPISGYMMKQSPHMQEGIKCMEGLKTSFPKTGKSKIGSIPRDTPWDENPRRKWDSSISQ 2040 LEPISGYMMKQSPHMQEGIKCMEGLKTSFPKTGKSKIGSIPRDTPWDENPRRKWDSSIS+ Sbjct: 1981 LEPISGYMMKQSPHMQEGIKCMEGLKTSFPKTGKSKIGSIPRDTPWDENPRRKWDSSISE 2040 Query: 2041 KTAWNQKNLQTVLKPLDFSSLMSSEYESRSYTLEFIGKKSMSPKCVTLKAKQLRILQLFN 2100 KTAWNQKNLQTVLKPLDFSSLMSSEYESRSYTLEFIGKKSMSPKCVTLKAKQLRILQLFN Sbjct: 2041 KTAWNQKNLQTVLKPLDFSSLMSSEYESRSYTLEFIGKKSMSPKCVTLKAKQLRILQLFN 2100 Query: 2101 IIRYSTENHRKKKQHRFKYKMKGKQWYTSIGEALLSATEYAKSTTSKSMIDKLLYNTAAR 2160 IIRYSTENHRKKKQHRFKYKMKGKQWYTSIGEALLSATEYAKSTTSKSMIDKLLYNTAAR Sbjct: 2101 IIRYSTENHRKKKQHRFKYKMKGKQWYTSIGEALLSATEYAKSTTSKSMIDKLLYNTAAR 2160 Query: 2161 CILSNRTRRQNLDGHITEEKEEVQENVAAIFLGLLDFFMPVLSDSKNQRNTAQLSEKEII 2220 CILSNRTRRQNLDGHITEEKEEVQENVAAIFLGLLDFFMPVLSDSKNQRNTAQLSEKEII Sbjct: 2161 CILSNRTRRQNLDGHITEEKEEVQENVAAIFLGLLDFFMPVLSDSKNQRNTAQLSEKEII 2220 Query: 2221 FNAKCLTMKEKKSSISQIHKINRESTRKHRKKCKSYLKTVSNRKCQENHGHITEEEEEVQ 2280 FNAKCLTMKEKKSSISQIHKINRESTRKHRKKCKSYLKTVSNRKCQENHGHITEEEEEVQ Sbjct: 2221 FNAKCLTMKEKKSSISQIHKINRESTRKHRKKCKSYLKTVSNRKCQENHGHITEEEEEVQ 2280 Query: 2281 ENSPATFLGPLDFFMPVLSDSKNQINTIQLSERKIILNPKCLTMKEKKPPISQIHKISRQ 2340 ENSPATFLGPLDFFMPVLSDSKNQINTIQLSERKIILNPKCLTMKEKKPPISQIHKIS Q Sbjct: 2281 ENSPATFLGPLDFFMPVLSDSKNQINTIQLSERKIILNPKCLTMKEKKPPISQIHKISGQ 2340 Query: 2341 FTTKHRKKLESNLKTKLKAMWQGENVADTFPNTTSFTPDSSDIKRQSGFQTEIDMRISGL 2400 FTTKHRKKLESNLKTKLKAMWQGENVADTFPNTTSFTPDSSDIKRQSGFQTEIDMRISGL Sbjct: 2341 FTTKHRKKLESNLKTKLKAMWQGENVADTFPNTTSFTPDSSDIKRQSGFQTEIDMRISGL 2400 Query: 2401 SHTQPTQIESLAEGIARYSDPIDKRRTSNLVKGAKLHDRESGEEKQEHLTEMDPFYAENF 2460 SHTQPTQIESLAEGIARYSDPIDKRRTSNLVKGAKLHDRESGEEKQEHLTEMDPFYAENF Sbjct: 2401 SHTQPTQIESLAEGIARYSDPIDKRRTSNLVKGAKLHDRESGEEKQEHLTEMDPFYAENF 2460 Query: 2461 MANTYLRKDRHLGKSEDVLLGETFFSKSQIYKGNSEKNVKIEKNKNGKESLKVGLARMEK 2520 MANTYLRKDRHLGKSEDVLLGETFFSKSQIYKGNSEKNVKIEKNKNGKESLKVGLARMEK Sbjct: 2461 MANTYLRKDRHLGKSEDVLLGETFFSKSQIYKGNSEKNVKIEKNKNGKESLKVGLARMEK 2520 Query: 2521 SDNCAELSEATDDAISNKYDKQNIGHSVLKENAFCNLAAIVPDSVGRHSPASEEMKRQNG 2580 SDNCAELSEATDDAISNKYDKQNIGHSVLKENAFCNLAAIVPDSVGRHSPASEEMKRQNG Sbjct: 2521 SDNCAELSEATDDAISNKYDKQNIGHSVLKENAFCNLAAIVPDSVGRHSPASEEMKRQNG 2580 Query: 2581 RLKMADRSSPQGRPLQAKQSAVSQSPDTAGYAVVSNNKEQKQNFKAQKTEAEVDLIDQEA 2640 RLKMADRSSPQGRPLQAKQSAVSQSPDTAGYAVVSNNKEQKQNFKAQKTEAEVDLIDQEA Sbjct: 2581 RLKMADRSSPQGRPLQAKQSAVSQSPDTAGYAVVSNNKEQKQNFKAQKTEAEVDLIDQEA 2640 Query: 2641 KINVAEEFNPESVFFSKIHPLQIENKKEFKTADWKTRADPKTFALPKKQQELCVSGTIWS 2700 KINVAEEFNPESVFFSKIHPLQIENKKEFKTADWKTRADPKTFALPKKQQELCVSGTIWS Sbjct: 2641 KINVAEEFNPESVFFSKIHPLQIENKKEFKTADWKTRADPKTFALPKKQQELCVSGTIWS 2700 Query: 2701 YPNPYTSISPKIIRHKDKAKTADVESTMHTKQIKLKAKRIPVSQLLEYGTASNKKELRGN 2760 YPNPYTSISPKIIRHKDKAKTADVESTMHTKQIKLKAKRI VSQLLEYGTASNKKELRGN Sbjct: 2701 YPNPYTSISPKIIRHKDKAKTADVESTMHTKQIKLKAKRITVSQLLEYGTASNKKELRGN 2760 Query: 2761 IQQQKSFQLSKNAVHRVLKAVYDSGYCVSSIKKLTEVKMEKDKPKDRTCILPQPKLEKPL 2820 IQQQKSFQLSKNAVHRVLKAVYDSGYCVSSIKKLTEVKMEKDKPKDRTCILPQPKLEKPL Sbjct: 2761 IQQQKSFQLSKNAVHRVLKAVYDSGYCVSSIKKLTEVKMEKDKPKDRTCILPQPKLEKPL 2820 Query: 2821 KEMQRSLSGCTDMSSILRKQEQDIREKEQKHQSISEDISQYYIGPLRISSQQINYSSFDA 2880 KEMQRSLSGCTDMSSILRKQEQDIREKEQKHQSISEDISQYYIGPLRISSQQINYSSFDA Sbjct: 2821 KEMQRSLSGCTDMSSILRKQEQDIREKEQKHQSISEDISQYYIGPLRISSQQINYSSFDA 2880 Query: 2881 PRIRTDEELEFLIAQRAKEKDVGIAKHSVSIPWEREGSKRLDIPLNSKGQNIFFTELDTS 2940 PRIRTDEELEFLIAQRAKEKDVGIAKHSVSIPWEREGSKRLDIPLNSKGQNIFFTELDTS Sbjct: 2881 PRIRTDEELEFLIAQRAKEKDVGIAKHSVSIPWEREGSKRLDIPLNSKGQNIFFTELDTS 2940 Query: 2941 QQKICQEQELLKQEDISMTNLGSMACPIMEPLHLENTGKVTEEEDVYINRKISSHVLGKE 3000 QQK CQEQELLKQEDISMTNLGSMACPIMEPLHLENTGKVTEEEDVYINRKISSHVLGKE Sbjct: 2941 QQKTCQEQELLKQEDISMTNLGSMACPIMEPLHLENTGKVTEEEDVYINRKISSHVLGKE 3000 Query: 3001 GLKETDIFVGSKGQKFLCTNSEVQHKVPAEQKEQVNPDHVPESILDSESFLSKDPLHLKQ 3060 GLKETDIFVGSKGQKFLCTNSEVQHKVPAEQKEQVNPDHVPESILDSESFLSKDPLHLKQ Sbjct: 3001 GLKETDIFVGSKGQKFLCTNSEVQHKVPAEQKEQVNPDHVPESILDSESFLSKDPLHLKQ 3060 Query: 3061 AVNTARKENVTISESFNENLWGKEQSKLDITLKSNRQKMDFSKKLRMKHLSNYYQNKENI 3120 AVNTARKENVTISESFNENLWGKEQSKLDITLKSNRQKMDFSKKLRMKHLSNYYQNKENI Sbjct: 3061 AVNTARKENVTISESFNENLWGKEQSKLDITLKSNRQKMDFSKKLRMKHLSNYYQNKENI 3120 Query: 3121 LESVLPCILHQLYIENPKKEGSAEEIMSSKVLSPMVEKASHEVGIPVDQPPCSEGIHLNI 3180 LESVLPCILHQLYIENPKKEGSAEEIMSSKVLSPMVEKASHEVGIPVDQPPCSEGIHLNI Sbjct: 3121 LESVLPCILHQLYIENPKKEGSAEEIMSSKVLSPMVEKASHEVGIPVDQPPCSEGIHLNI 3180 Query: 3181 KGRKEHPQESTHEAFPASVSHSLMDVLQIKSPKVKKALKAINSLGYLTSNTKGIGLLFPR 3240 KGRKEHPQESTHEAFPASVSHSLMDVLQIKSPKVKKALKAINSLGYLTSNTKGIGLLFPR Sbjct: 3181 KGRKEHPQESTHEAFPASVSHSLMDVLQIKSPKVKKALKAINSLGYLTSNTKGIGLLFPR 3240 Query: 3241 QAEKEEKYTYKALPKPASHSKTDLFQFNASMQQEKLDAMDIPHYDYLTSQTREAVKQMDV 3300 QAEKEEKYTYKALPKPASHSKTDLFQFNASMQQEKLDAMDIPHYDYLTSQTREAVKQMDV Sbjct: 3241 QAEKEEKYTYKALPKPASHSKTDLFQFNASMQQEKLDAMDIPHYDYLTSQTREAVKQMDV 3300 Query: 3301 IVGYTQNSKKRQDLLKTGQKWQYLPISYENFWEHISCPQKYPCLLQHLMPQEKEALSEGG 3360 IVGYTQNSKKRQDLLKTGQKWQYLPISYENFWEHISCPQKYPCLLQHLMPQEKEALSEGG Sbjct: 3301 IVGYTQNSKKRQDLLKTGQKWQYLPISYENFWEHISCPQKYPCLLQHLMPQEKEALSEGG 3360 Query: 3361 NLSSRTPGLDLFSADQLSTITKNRLEWIVPLISPRQMKKQDSMLPLGSYHKTIKYASLLF 3420 NLSSRTPGLDLFSADQLSTITKNRLEWIVPLISPRQMKKQDSMLPLGSYHKTIKYASLLF Sbjct: 3361 NLSSRTPGLDLFSADQLSTITKNRLEWIVPLISPRQMKKQDSMLPLGSYHKTIKYASLLF 3420 Query: 3421 PKGMKSSDGVQVFDLISNNSSPKLRLGKKIETQKANEKVQKEVCLPITLHSLSASMPILQ 3480 PKGMKSSDGVQVFDLISNNSSPKLRLGKKIETQKANEKVQKEVCLPITLHSLSASMPILQ Sbjct: 3421 PKGMKSSDGVQVFDLISNNSSPKLRLGKKIETQKANEKVQKEVCLPITLHSLSASMPILQ 3480 Query: 3481 ESKGQKDSVEQVIRKGVICHKRRTSKWKKSVFSHILNTSDCGASSNRLEMQWNMTDKMVN 3540 ESKGQKDSVEQVIRKGVICHKRRTSKWKKSVFSHILNTSDCGASSNRLEMQWNMTDKMVN Sbjct: 3481 ESKGQKDSVEQVIRKGVICHKRRTSKWKKSVFSHILNTSDCGASSNRLEMQWNMTDKMVN 3540 Query: 3541 VKHRMSEIDLVAAKICESILSLPHFKLNKETIDGVISSNVKSTKQHISQGKNDRVKAMDM 3600 VKHRMSEIDLVAAKICESILSLPHFKLNKETIDGVISSNVKSTKQHISQGKNDRVKAMDM Sbjct: 3541 VKHRMSEIDLVAAKICESILSLPHFKLNKETIDGVISSNVKSTKQHISQGKNDRVKAMDM 3600 Query: 3601 KRIKSPNIILKPRKSSLSHILSIKEFPLLLDIIKQEGKMQEGKGKSSMKLTNLCTSLPSL 3660 KRIKSPNIILKPRKSSLSHILSIKEFPLLLDIIKQEGKMQEGKGKSSMKLTNLCTSLPSL Sbjct: 3601 KRIKSPNIILKPRKSSLSHILSIKEFPLLLDIIKQEGKMQEGKGKSSMKLTNLCTSLPSL 3660 Query: 3661 SHSNSNSRTKAGKDKSGTLKGCLPPLKLQASSNARRVSSAESINRDSLSNVIESKCFPQK 3720 SHSNSNSRTKAGKDKSGTLKGCLPPLKLQASSNARRVSSAESINRDSLSNVIESKCFPQK Sbjct: 3661 SHSNSNSRTKAGKDKSGTLKGCLPPLKLQASSNARRVSSAESINRDSLSNVIESKCFPQK 3720 Query: 3721 KKEDRENIVDVKDIMGLKCITLKGKKSLFRHLLHGKEPQRSNKKLEKMTQEDESNLNVVQ 3780 KKEDRENIVDVKD+MGLKCITLKGKKSLFRHLLHGKEPQRSNKKLEKMTQEDESNLNVVQ Sbjct: 3721 KKEDRENIVDVKDVMGLKCITLKGKKSLFRHLLHGKEPQRSNKKLEKMTQEDESNLNVVQ 3780 Query: 3781 NKLCASILSPPHLEWNPRIKEVYMRGITRFCLSSSTQQELSDTMEKCEQPIDDSLSSIEK 3840 NKLCASILSPPHLEWNPRIKEVYMRGITRFCLSSSTQQELSDTMEKCEQPIDDSLSSIEK Sbjct: 3781 NKLCASILSPPHLEWNPRIKEVYMRGITRFCLSSSTQQELSDTMEKCEQPIDDSLSSIEK 3840 Query: 3841 AKHMPQKDKDRVEKALEKIMHSKRIALEVKQPSIFQELELNIKEKGGKIQEDKEVEIWSK 3900 AKHMPQKDKDRVEKALEKIMHSKRIALEVKQPSIFQELELNIKEKGGKIQEDKEVEIWSK Sbjct: 3841 AKHMPQKDKDRVEKALEKIMHSKRIALEVKQPSIFQELELNIKEKGGKIQEDKEVEIWSK 3900 Query: 3901 PFASISFLPYSKVGTIEGEEAMRIKMRSSFSQPNLQESSDTEKTAYEKCISDNISNSVKK 3960 PFASISFLPYSKVGTIEGEEAMRIKMRSSFSQPNLQESSDTEKTAYEKCISDNISNSVKK Sbjct: 3901 PFASISFLPYSKVGTIEGEEAMRIKMRSSFSQPNLQESSDTEKTAYEKCISDNISNSVKK 3960 Query: 3961 ALESILQKEQRQKMEKIRALKKMKSSISQGIQLDIKEQEKRIEHIKGEPSVLLTNACASI 4020 ALESILQKEQRQKMEKIRALKKMKSSISQGIQLDIKEQEKRIEHIKGEPSVLLTNACASI Sbjct: 3961 ALESILQKEQRQKMEKIRALKKMKSSISQGIQLDIKEQEKRIEHIKGEPSVLLTNACASI 4020 Query: 4021 PSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEAGEKADGVASKGDITIKVQKAKDY 4080 PSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEAGEKADGVASKGDITIKVQKAKDY Sbjct: 4021 PSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEAGEKADGVASKGDITIKVQKAKDY 4080 Query: 4081 MQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPLNTKEPGKMDQEAQEQGKEDREGE 4140 MQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPLNTKEPGKMDQEAQEQGKEDREGE Sbjct: 4081 MQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPLNTKEPGKMDQEAQEQGKEDREGE 4140 Query: 4141 EQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADGVGIEQGKMDGDKNEQERVLFLYL 4200 EQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADGVGIEQGKMDGDKNEQERVLFLYL Sbjct: 4141 EQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADGVGIEQGKMDGDKNEQERVLFLYL 4200 Query: 4201 PSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSSETGKKANGVPSEGDSASEVQKA 4260 PSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSSETGKKANGVPSEGDSASEVQKA Sbjct: 4201 PSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSSETGKKANGVPSEGDSASEVQKA 4260 Query: 4261 KDYMQQKEEDESKQETVLFLHLPSESSLTCYELNTRKEGEEDLQGIIKSATLQLRQQKSF 4320 KDYMQQKEEDESKQETVLFLHLPSESSLTCYELNTRKEGEEDLQGIIKSATLQLRQQKSF Sbjct: 4261 KDYMQQKEEDESKQETVLFLHLPSESSLTCYELNTRKEGEEDLQGIIKSATLQLRQQKSF 4320 Query: 4321 DAGKIAHTKSFGVDSSNDVKTVQEYKPQKEVDRGKTVSVDYIMQPEGTIFEAEQLSLPHT 4380 DAGKIAHTKSFGVDSSNDVKTVQEYKPQKEVDRGKTVSVDYIMQPEGTIFEAEQLSLPHT Sbjct: 4321 DAGKIAHTKSFGVDSSNDVKTVQEYKPQKEVDRGKTVSVDYIMQPEGTIFEAEQLSLPHT 4380 Query: 4381 LNIPGSSGSKTREVLTNIKEKLRHVQERKSELDVFLTIPSLSHCKLDKRTAGKKEEQGVT 4440 LNIPGSSGSKTREVLTNIKEKLRHVQERKSELDVFLTIPSLSHCKLDKRTAGKKEEQGVT Sbjct: 4381 LNIPGSSGSKTREVLTNIKEKLRHVQERKSELDVFLTIPSLSHCKLDKRTAGKKEEQGVT 4440 Query: 4441 RSFLPPSWHMESSDTGKLKYTLSYLNDITGDSNRTKYMAQIQKDKANISEKSVMHPEYIA 4500 RSFLPPSWHMESSDTGKLKYTLSYLNDITGDSNRTKYMAQIQKDKANISEKSVMHPEYIA Sbjct: 4441 RSFLPPSWHMESSDTGKLKYTLSYLNDITGDSNRTKYMAQIQKDKANISEKSVMHPEYIA 4500 Query: 4501 VKAEKSPLSHILKTKELQVNISQQGEKAQEGEVEIVVLLSKTCPFVTSSAFLELDSIKEE 4560 VKAEKSPLSHILKTKELQVNISQQGEKAQEGEVEIVVLLSKTCPFVTSSAFLELDSIKEE Sbjct: 4501 VKAEKSPLSHILKTKELQVNISQQGEKAQEGEVEIVVLLSKTCPFVTSSAFLELDSIKEE 4560 Query: 4561 EGEPRITRSFMPHLEIQESLPSRQTAPTKPTESLVKKEKQLLPQKEDRVQTVSMHGLMHP 4620 EGEPRITRSFMPHLEIQESLPSRQTAPTKPTESLVKKEKQLLPQKEDRVQTVSMHGLMHP Sbjct: 4561 EGEPRITRSFMPHLEIQESLPSRQTAPTKPTESLVKKEKQLLPQKEDRVQTVSMHGLMHP 4620 Query: 4621 NGAVFKAKTSAPPQVFSITEHSPLSKRKEPQWGMKERAGQKQDRTGRPHVILTKTHPFMP 4680 NGAVFKAKTSAPPQVFSITEHSPLSKRKEPQWGMKERAGQKQDRTGRPHVILTKTHPFMP Sbjct: 4621 NGAVFKAKTSAPPQVFSITEHSPLSKRKEPQWGMKERAGQKQDRTGRPHVILTKTHPFMP 4680 Query: 4681 SLSHHRFSPSQPKLPISSGAGKSRLANSNEGISSHKVILKANQQMPYKEAKDRVKIEGRE 4740 SLSHHRFSPSQPKLPISSGAGKSRLANSNEGISSHKVILKANQQMPYKEAKDRVKIEGRE Sbjct: 4681 SLSHHRFSPSQPKLPISSGAGKSRLANSNEGISSHKVILKANQQMPYKEAKDRVKIEGRE 4740 Query: 4741 GRILPKRIHLRAEALPLALLCNGKNYSLHIEEQGEGVQESKKEPGVVPRKPASFPPPPFY 4800 GRILPKRIHLRAEALPLALLCNGKNYSLHIEEQGEGVQESKKEPGVVPRK ASFPPPPFY Sbjct: 4741 GRILPKRIHLRAEALPLALLCNGKNYSLHIEEQGEGVQESKKEPGVVPRKSASFPPPPFY 4800 Query: 4801 LNCDTRRNEKEGTLGKTQFSFPPLKIQDSSDSGKKAYTESLHGYTLSNSKGPVQPTAQGE 4860 LNCDTRRNEKEGTLGKTQFSFPPLKIQDSSDSGKKAYTESLHGYTLSNSKGPVQPTAQGE Sbjct: 4801 LNCDTRRNEKEGTLGKTQFSFPPLKIQDSSDSGKKAYTESLHGYTLSNSKGPVQPTAQGE 4860 Query: 4861 EKGGLRIDMEDKMLPKCTDLKAKQLLLSDILNTKKLQWKSKEQKRKIQEDKNKQVKGLPS 4920 EKGGLRIDMEDKMLPKCTDLKAKQLLLSDILNTKKLQWKSKEQKRKIQEDKNKQVKGLPS Sbjct: 4861 EKGGLRIDMEDKMLPKCTDLKAKQLLLSDILNTKKLQWKSKEQKRKIQEDKNKQVKGLPS 4920 Query: 4921 INTSLLTPPYLKFDTTEGQENVIRIAKVSLPQSRSKESSDAGRIACPEATHGELSSDVKQ 4980 INTSLLTPPYLKFDTTEGQENVIRIAKVSLPQSRSKESSDAGRIACPEATHGELSSDVKQ Sbjct: 4921 INTSLLTPPYLKFDTTEGQENVIRIAKVSLPQSRSKESSDAGRIACPEATHGELSSDVKQ 4980 Query: 4981 LKAHLLQKEEKDREKVADMTSVLDPNKMYLKAKKSPVLHTHSFSDLQWKTREQEEEKVQK 5040 LKAHLLQKEEKDREKVADMTSVLDPNKMYLKAKKSPVLHTHSFSDLQWKTREQEEEKVQK Sbjct: 4981 LKAHLLQKEEKDREKVADMTSVLDPNKMYLKAKKSPVLHTHSFSDLQWKTREQEEEKVQK 5040 Query: 5041 VKSGPGVMLSKSPSRSSPLHLNVNTGFQEESIPILTRPSFPLVKLQVSPDTEGGTCIRPI 5100 VKSGPGVMLSKSPSRSSPLHLNVNTGFQEESIPILTRPSFPLVKLQVSPDTEGGTCIRPI Sbjct: 5041 VKSGPGVMLSKSPSRSSPLHLNVNTGFQEESIPILTRPSFPLVKLQVSPDTEGGTCIRPI 5100 Query: 5101 AGDILIYLQKGKHVSQNKEEDDVQIVSILIFPKHQEEKVQECEGEPGVVLTKSTSLPSLS 5160 AGDILIYLQKGKHVSQNKEEDDVQIVSILIFPKHQEEKVQECEGEPGVVLTKSTSLPSLS Sbjct: 5101 AGDILIYLQKGKHVSQNKEEDDVQIVSILIFPKHQEEKVQECEGEPGVVLTKSTSLPSLS 5160 Query: 5161 QLELDKETHLGNEMLRLKRPILRRISHIGETVHRESVVGDIPKDVKNEKQHIPQKEERNQ 5220 QLELDKETHLGNEMLRLKRPILRRISHIGETVHRESVVGDIPKDVKNEKQHIPQKEERNQ Sbjct: 5161 QLELDKETHLGNEMLRLKRPILRRISHIGETVHRESVVGDIPKDVKNEKQHIPQKEERNQ 5220 Query: 5221 KKIIDMRGTDITLKSKKSPRSCMLHRTELHVNIGGQGRKEHEGQDKPPGMIQRKMCILFS 5280 KKIIDMRGTDITLKSKKSPRSCMLHRTELHVNIGGQGRKEHEGQDKPPGMIQRKMCILFS Sbjct: 5221 KKIIDMRGTDITLKSKKSPRSCMLHRTELHVNIGGQGRKEHEGQDKPPGMIQRKMCILFS 5280 Query: 5281 KPLPSNLKLERATHADEERLGGKTSFVLPLMPSALPDTEKTADAEARSGDVRKGKPHRSQ 5340 KPLPSNLKLERATHADEERLGGKTSFVLPLMPSALPDTEKTADAEARSGDVRKGKPHRSQ Sbjct: 5281 KPLPSNLKLERATHADEERLGGKTSFVLPLMPSALPDTEKTADAEARSGDVRKGKPHRSQ 5340 Query: 5341 KENRHEVKTIDMRFRIHCQEARISPMSHILNAKELVLNINKLEKKVHKDKDEACVVLSRT 5400 KENRHEVKTIDMRFRIHCQEARISPMSHILNAKELVLNINKLEKKVHKDKDEACVVLSRT Sbjct: 5341 KENRHEVKTIDMRFRIHCQEARISPMSHILNAKELVLNINKLEKKVHKDKDEACVVLSRT 5400 Query: 5401 FLSIPSAPPLYLDSGNKTDKDTPGITGSSCPQRTLHVPSNTQKITNRDSVEGVDKNVVKQ 5460 FLSIPSAPPLYLDSGNKTDKDTPGITGSSCPQRTLHVPSNTQKITNRDSVEGVDKNVVKQ Sbjct: 5401 FLSIPSAPPLYLDSGNKTDKDTPGITGSSCPQRTLHVPSNTQKITNRDSVEGVDKNVVKQ 5460 Query: 5461 AEQYVPRPEAEQQLTSNFMISVQQRNQPSRVTSEEDLNQLVLNSRDEDIYFTGFGTIRSG 5520 AEQYVPRPEAEQQLTSNFMISVQQRNQPSRV SEEDLNQLVLNSRDEDIYFTGFGTIRSG Sbjct: 5461 AEQYVPRPEAEQQLTSNFMISVQQRNQPSRVRSEEDLNQLVLNSRDEDIYFTGFGTIRSG 5520 Query: 5521 KRPEWLFTGKKAQPVKYKTETLTAFLSYPTMDATKMGGLEEDTEIMDNLNHKISPKASVS 5580 KRPEWLFTGKKAQPVKYKTETLTAFLSYPTMDATKMGGLEEDTEIMDNLNHKISPKASVS Sbjct: 5521 KRPEWLFTGKKAQPVKYKTETLTAFLSYPTMDATKMGGLEEDTEIMDNLNHKISPKASVS 5580 Query: 5581 LIRKISKELYVTLGTPASSKGFSVSERYAHQQETSSKVSPELAGSCKFDKPKEDGQSNDR 5640 LIRKISKELYVTLGTPA+SKGFSVSERYAHQQETSSKVSPELAGSCKFDKPKEDGQSNDR Sbjct: 5581 LIRKISKELYVTLGTPANSKGFSVSERYAHQQETSSKVSPELAGSCKFDKPKEDGQSNDR 5640 Query: 5641 ISKMFSPKVLAPQTKGSLKKISIVTNWNAPQNIEEQDIVMKKQVIRRCEHGHKTRTNTIL 5700 ISKMFSPKVLAPQTKGSLKKISIVTNWNAPQNIEEQDIVMKKQVIRRCEHGHKTRTNTIL Sbjct: 5641 ISKMFSPKVLAPQTKGSLKKISIVTNWNAPQNIEEQDIVMKKQVIRRCEHGHKTRTNTIL 5700 Query: 5701 SKFPLQSGKQKTPSETDVDKKTTAHLSLQMLPGIHMDMTEIDPAKGGRKQALLISEQEEG 5760 SKFPLQSGKQKTPSETDVDKKTTAHLSLQMLPGIHMDMTEIDPAKGGRKQALLISEQEEG Sbjct: 5701 SKFPLQSGKQKTPSETDVDKKTTAHLSLQMLPGIHMDMTEIDPAKGGRKQALLISEQEEG 5760 Query: 5761 VLELLPKSLFPPWTFQFQSGDLEEKHQTDANTNINLEQKKLEMDNDSTVNQKEGKLKIGT 5820 VLE LPKSLFPPWTFQFQSGDLEEKHQTDANTNINLEQKKLEMDNDSTVNQKEGKLKIGT Sbjct: 5761 VLEFLPKSLFPPWTFQFQSGDLEEKHQTDANTNINLEQKKLEMDNDSTVNQKEGKLKIGT 5820 Query: 5821 NRALHLQEEKTEMHKARTANLEKERGRMDTSSSAHPHLPSLKAEESQMKTQVITHRENSR 5880 NRALHLQEEKTEMHKARTANLEKERGRMDTSSSAHPHL SLKAEESQMKTQVITHRENSR Sbjct: 5821 NRALHLQEEKTEMHKARTANLEKERGRMDTSSSAHPHLLSLKAEESQMKTQVITHRENSR 5880 Query: 5881 LIMQKQKKELEASNAKQSIQLQKLFQRNVLDSFYSYVPLSPKCKDQKGRLTIRDLKRELS 5940 LIMQKQKKELEASNAKQSIQLQKLFQRNVLDSFYSYVPLSPK KDQKGRLTIRDLKRELS Sbjct: 5881 LIMQKQKKELEASNAKQSIQLQKLFQRNVLDSFYSYVPLSPKRKDQKGRLTIRDLKRELS 5940 Query: 5941 TKYLTMKIQNHPIPQMLNITGRGTPSNRKKLEYDVKLKNIASWSKDVSGIFIRSLSISIM 6000 TKYLTMKIQNHPIPQMLNITGRGTPSNRKKLEYDVKLKNIASWSKDVSGIFIRSLSISIM Sbjct: 5941 TKYLTMKIQNHPIPQMLNITGRGTPSNRKKLEYDVKLKNIASWSKDVSGIFIRSLSISIM 6000 Query: 6001 RSPHTDPKTNLEREKRICLPKFQEKSPNTSEMSKRDTLTIVKGEQNFTNTVPQDPQPFAV 6060 RSPHTDPKTNLEREKRICLPKFQEKSPNTSEMSKRDTLTIVKGEQNFTNTVPQDPQPFAV Sbjct: 6001 RSPHTDPKTNLEREKRICLPKFQEKSPNTSEMSKRDTLTIVKGEQNFTNTVPQDPQPFAV 6060 Query: 6061 DKQQMQKLPNVKSEANLRSEMNKKYLKAQTKERIVPEHDVSRIIKKPDLRIIEQEEKILK 6120 DKQQMQKLPNVKSEANLRSEMNKKYLKAQTKERIVPEHDVSRIIKKPDLRIIEQEEKILK Sbjct: 6061 DKQQMQKLPNVKSEANLRSEMNKKYLKAQTKERIVPEHDVSRIIKKPDLRIIEQEEKILK 6120 Query: 6121 RILTPTECPSMLEDPKLPKQRDQSEPVWDMTTQKVQQQKAFPGTVPIPPQVKSSEVKIVA 6180 RILTPTECPSMLEDPKLPKQRDQSEPVWDMTTQKVQQQKAFPGTVPIPPQVKSSEVKIVA Sbjct: 6121 RILTPTECPSMLEDPKLPKQRDQSEPVWDMTTQKVQQQKAFPGTVPIPPQVKSSEVKIVA 6180 Query: 6181 DSTNAEHLLPICEATKAISESQVKNMIQDKVSSDKLDNIQAYKPDDLKSPPFPEGPDTIS 6240 DSTNAEHLLPICEATKAISESQVKNMIQDKVSSDKLDNIQAYKPDDLKSPPFPEGPDTIS Sbjct: 6181 DSTNAEHLLPICEATKAISESQVKNMIQDKVSSDKLDNIQAYKPDDLKSPPFPEGPDTIS 6240 Query: 6241 TAIYPKTQHKSLLEQFTPKEKNKLTSHLESKALEIQLNLIPEMARKSLQMFNFYPKGTIS 6300 TAIYPKTQHKSLLEQFTPKEKNKLTSHLESKALEIQLNLIPEMARKSLQMFNFYPKGTIS Sbjct: 6241 TAIYPKTQHKSLLEQFTPKEKNKLTSHLESKALEIQLNLIPEMARKSLQMFNFYPKGTIS 6300 Query: 6301 KDNSWRFYSRHKTMNFMSLEGTDTIEPNSKHKHQKDSPLASNMKTLIVDVSSDSEETITK 6360 KDNSWRFYSRHKTMNFMSLEGTDTIEPNSKHKHQKDSPLASNMKTLIVDVSSDSEETITK Sbjct: 6301 KDNSWRFYSRHKTMNFMSLEGTDTIEPNSKHKHQKDSPLASNMKTLIVDVSSDSEETITK 6360 Query: 6361 LQSINKLENGTSAVTSASEMLLPHTLQNHSVKEKGKLLMHFSVKTLEIQMKAFPRIVRES 6420 LQSINKLENGTSAVTSASEMLLPHTLQNHSVKEKGKLLMHFSVKTLEIQMKAFPRIVRES Sbjct: 6361 LQSINKLENGTSAVTSASEMLLPHTLQNHSVKEKGKLLMHFSVKTLEIQMKAFPRIVRES 6420 Query: 6421 YAMTSAHERKKPLSNCIHPGFTGPKRQNRILLLSEEKSLHQIDLDLQYKYLRFLLGLPVG 6480 YAMTSAHERKKPLSNCIHPGFTGPKRQNRILLLSEEKSLHQIDLDLQYKYLRFLLGLPVG Sbjct: 6421 YAMTSAHERKKPLSNCIHPGFTGPKRQNRILLLSEEKSLHQIDLDLQYKYLRFLLGLPVG 6480 Query: 6481 STFPKPNVLPKHSKLNTIAVCKNVNAGGQSGSLSIDTELLEQHISFKKQSPHENSSLIRK 6540 STFPKPNVLPKHSKLNTIAVCKNVNAGGQSGSLSIDTELLEQHISFKKQSPHENSSLIRK Sbjct: 6481 STFPKPNVLPKHSKLNTIAVCKNVNAGGQSGSLSIDTELLEQHISFKKQSPHENSSLIRK 6540 Query: 6541 FPQPTLVCASDRDLHSPRKKDTQVLSESEFHVTPEKNKQYHVWFQERNTCESVDLRTQRN 6600 FPQPTLVCASDRDLHSPRKKDTQVLSESEFHVTPEKNKQYHVWFQERNTCESVDLRTQRN Sbjct: 6541 FPQPTLVCASDRDLHSPRKKDTQVLSESEFHVTPEKNKQYHVWFQERNTCESVDLRTQRN 6600 Query: 6601 ATGSAVSCETQISEDFVDIQTDIESPADLDECSCLEVSESEECVFLEANSYLSQESENIL 6660 ATGSAVSCETQISEDFVDIQTDIESPADLDECSCLEVSESEECVFLEANSYLSQESENIL Sbjct: 6601 ATGSAVSCETQISEDFVDIQTDIESPADLDECSCLEVSESEECVFLEANSYLSQESENIL 6660 Query: 6661 FELQTGIPLENVYKITTDLKSFYSEDSGSHCTRECRKETLIITPPSCKSHKSRKYRSSSK 6720 FELQTGIPLENVYKITTDLKSFYSEDSGSHCTRECRKETLIITPPSCKSHKSRKYRSSSK Sbjct: 6661 FELQTGIPLENVYKITTDLKSFYSEDSGSHCTRECRKETLIITPPSCKSHKSRKYRSSSK 6720 Query: 6721 MKSPDWLCHSSSNTAEIQSRSSSVSFSEEKISWTTKSRTSYSSAPLTESNIKSHLAKNQG 6780 MKSPDWLCHSSSNTAEIQSRSSSVSFSEEKISWTTKSRTSYSSAPLTESNIKSHLAKNQG Sbjct: 6721 MKSPDWLCHSSSNTAEIQSRSSSVSFSEEKISWTTKSRTSYSSAPLTESNIKSHLAKNQG 6780 Query: 6781 KSHRHPESQERKKARSDLFRKNSSHWDHDYSCTHSKGKRDRKKRVYDYESERLDCFQSKH 6840 KSHRHPESQERKKARSDLFRKNSSHWDHDYSCTHSKGKRDRKKRVYDYESERLDCFQSKH Sbjct: 6781 KSHRHPESQERKKARSDLFRKNSSHWDHDYSCTHSKGKRDRKKRVYDYESERLDCFQSKH 6840 Query: 6841 KSASKPHHDDINFYSERKQNRPFFFACVPADSLEVIPKTIRWTIPPETLRKRNFRIPLVA 6900 KSASKPHHDDINFYSERKQNRPFFFACVPADSLEVIPKTIRWTIPPETLRKRNFRIPLVA Sbjct: 6841 KSASKPHHDDINFYSERKQNRPFFFACVPADSLEVIPKTIRWTIPPETLRKRNFRIPLVA 6900 Query: 6901 KISSSWNIWSSSKKLLGSLSGSLTTVFHS 6929 KISSSWNIWSSSKKLLGSLSGSLTTVFHS Sbjct: 6901 KISSSWNIWSSSKKLLGSLSGSLTTVFHS 6929 >gi|226246554 hypothetical protein LOC643677 [Homo sapiens] Length = 7081 Score = 1.341e+04 bits (34798), Expect = 0.0 Identities = 6811/7034 (96%), Positives = 6843/7034 (97%), Gaps = 112/7034 (1%) Query: 1 MKACASFWKKPTLPEKGSSDVQELQ-----------------------RIGQLLIHLQEK 37 MKACASFWKKPTLPEKGSSDVQE + R+G L Sbjct: 55 MKACASFWKKPTLPEKGSSDVQETEDSCPKSRKLAPENWSVINSSSGERVGTFL------ 108 Query: 38 EKRITSSLTSEEKECNFEDRILFSREILWSGTSESEDQVSPSSESHVPSSNGISSSLPLF 97 EKRITSSLTSEEKECNFEDRILFSREILWSGTSESEDQVSPSSESHVPSSNGISSSLPLF Sbjct: 109 EKRITSSLTSEEKECNFEDRILFSREILWSGTSESEDQVSPSSESHVPSSNGISSSLPLF 168 Query: 98 YSEVEETCLSHTEHPDREYETIQFSSKKLFSMMKTNKNKNSGFSSDLSFSASRFTVENED 157 YSEVEETCLSHTEHPDREYETIQFSSKKLFSMMKTNKNKNSGFSSDLSFSASRFTVENED Sbjct: 169 YSEVEETCLSHTEHPDREYETIQFSSKKLFSMMKTNKNKNSGFSSDLSFSASRFTVENED 228 Query: 158 LDVAPCPLAHLFLSRDQVRLLEENVRNQIPSKPKTKLGSRTTYQCSRSQESLNQNQPSVG 217 LDVAPCPLAHLFLSRDQVRLLEENVRNQIPSKPKTKLGSRTTYQCSRSQESLNQNQPSVG Sbjct: 229 LDVAPCPLAHLFLSRDQVRLLEENVRNQIPSKPKTKLGSRTTYQCSRSQESLNQNQPSVG 288 Query: 218 MVISVQAQDSFPGQNAFQNQGLYEVQFTSQAQYINHNQESIKSQPESKASNFAQPEDVMK 277 MVISVQAQDSFPGQNAFQNQGLYEVQFTSQAQYINHNQESIKSQPESKASNFAQPEDVMK Sbjct: 289 MVISVQAQDSFPGQNAFQNQGLYEVQFTSQAQYINHNQESIKSQPESKASNFAQPEDVMK 348 Query: 278 KPFSSSTQDSFQSQDLDRNQHFVEVPSIVEAKYSVKGLESDEHLGEDQHCVWFIDSNKVK 337 KPFSSSTQDSFQSQDLDRNQHFVEVPSIVEAKYSVKGLESDEHLGEDQHCVWFIDSNKVK Sbjct: 349 KPFSSSTQDSFQSQDLDRNQHFVEVPSIVEAKYSVKGLESDEHLGEDQHCVWFIDSNKVK 408 Query: 338 YSIKGQDTIFKNAEFLVLTLNPNLVTEDMPQLRSVKAQGQQQIVSSELNQDSVYSSVPLL 397 YSIKGQDTIFKNAEFLVLTLNPNLVTEDMPQLRSVKAQGQQQIVSSELNQDSVYSSVPLL Sbjct: 409 YSIKGQDTIFKNAEFLVLTLNPNLVTEDMPQLRSVKAQGQQQIVSSELNQDSVYSSVPLL 468 Query: 398 STIKGQKNRRKTPDSKSKLSLNVPSLKAKKTPTSQVFQITVCHTLKNRNELGCKNNTEKK 457 STIKGQKNRRKTPDSKSKLSLNVPSLKAKKTPTSQVFQITVCHTLKNRNELGCKNNTEKK Sbjct: 469 STIKGQKNRRKTPDSKSKLSLNVPSLKAKKTPTSQVFQITVCHTLKNRNELGCKNNTEKK 528 Query: 458 ELHERKDISDIALHLISVSKLILPYVKNYSRKQLVKVMPGLIKCGHFLQKQNKSPDTEKI 517 ELHERKDISDIALHLISVSKLILPYVKNYSRKQLVKVMPGLIKCGHFLQKQNKSPDTEKI Sbjct: 529 ELHERKDISDIALHLISVSKLILPYVKNYSRKQLVKVMPGLIKCGHFLQKQNKSPDTEKI 588 Query: 518 NYAGPLEETGISDITKKEKEYDKENKRLKNISPKMLPQLEQSFMVNTVQLKAPCLLVETN 577 NYAGPLEETGISDITKKEKEYDKENKRLKNISPKMLPQLEQSFMVNTVQLKAPCLLVETN Sbjct: 589 NYAGPLEETGISDITKKEKEYDKENKRLKNISPKMLPQLEQSFMVNTVQLKAPCLLVETN 648 Query: 578 GKSKESLKDSITQAKGIGITEFHVLNSKKPFDLHIPKHKTSLEEAISKPMQKLVSSPEME 637 GKSKESLKDSITQAKGIGITEFHVLNSKKPFDLHIPKHKTSLEEAISKPMQKLVSSPEME Sbjct: 649 GKSKESLKDSITQAKGIGITEFHVLNSKKPFDLHIPKHKTSLEEAISKPMQKLVSSPEME 708 Query: 638 SNNRMKIQEDLQSSENSHLQLSNGEELPTSTPKTQRCFPRENTQKQKDFLELVLELSNVG 697 SNNRMKIQEDLQSSENSHLQLSNGEELPTSTPKTQRCFPRENTQKQKDFLELVLELSNVG Sbjct: 709 SNNRMKIQEDLQSSENSHLQLSNGEELPTSTPKTQRCFPRENTQKQKDFLELVLELSNVG 768 Query: 698 LLISLGSKMHKSSEELEAIKIQVNTESVNLKESKPLILNVTEDSDLRESEELECNTGSNI 757 LLIS GSKMHKSSEELEAIKIQVNTESVNLKESKPLILNVTEDSDLRESEELECNTGSNI Sbjct: 769 LLISPGSKMHKSSEELEAIKIQVNTESVNLKESKPLILNVTEDSDLRESEELECNTGSNI 828 Query: 758 TNMHQDKETSDAFHSATYTTISQLPDTETHSISKAKADTLRIIRLSHSASKQEKLPDEKE 817 TNMHQDKETSDAFHSATYTTISQLPDTETHSISKAKADTLRIIRLSHSASKQEKLPDEKE Sbjct: 829 TNMHQDKETSDAFHSATYTTISQLPDTETHSISKAKADTLRIIRLSHSASKQEKLPDEKE 888 Query: 818 TQNAEYIDKSCTFKKPQQCDRKEQEKEANSELTQGFRFSIHLKQKPKYVKFQMEQISSGS 877 TQNAEYIDKSCTFKKPQQCDRKEQEKEANSELTQGFRFSIHLKQKPKYVKFQMEQISSGS Sbjct: 889 TQNAEYIDKSCTFKKPQQCDRKEQEKEANSELTQGFRFSIHLKQKPKYVKFQMEQISSGS 948 Query: 878 SKAPNKEQEVQPQTLSTQTILENSPCPMMDPFQVEKVKQSTDRPTDRESAGDPKNPLTMP 937 SKAPNKEQEVQPQTLSTQTILENSPCPMMDPFQVEKVKQSTDRPTDRESAGDPKNPLTMP Sbjct: 949 SKAPNKEQEVQPQTLSTQTILENSPCPMMDPFQVEKVKQSTDRPTDRESAGDPKNPLTMP 1008 Query: 938 ENLPVGELLIETTEYSVPFGGNLQKTTDSHIAEEKEDVKRYLPAVALGSFNNHLLTLPYF 997 ENLPVGELLIETTEYSVPFGGNLQKTTDSHIAEEKEDVKRYLPAVALGSFNNHLLTLPYF Sbjct: 1009 ENLPVGELLIETTEYSVPFGGNLQKTTDSHIAEEKEDVKRYLPAVALGSFNNHLLTLPYF 1068 Query: 998 KRQEIKKKLSETKSVLSVKYVIMKVKKPAISLMPYINICGTSNHRKKMGGNFEIIIKQIL 1057 KRQEIKKKLSETKSVLSVKYVIMKVKKPAISLMPYINICGTSNHRKKMGGNFEIIIKQIL Sbjct: 1069 KRQEIKKKLSETKSVLSVKYVIMKVKKPAISLMPYINICGTSNHRKKMGGNFEIIIKQIL 1128 Query: 1058 QDKIAAGMLLNVIYPPMSILPNTRMYSRLNAENHSHIKLVQEESQIEREEKYPYFINEGN 1117 QDKIAAGMLLNVIYPPMSILPNTRMYSRLNAENHSHIKLVQEESQIEREEKYPYFINEGN Sbjct: 1129 QDKIAAGMLLNVIYPPMSILPNTRMYSRLNAENHSHIKLVQEESQIEREEKYPYFINEGN 1188 Query: 1118 ESQNTLDAKLQDEVKGVKETLPKAVLHDSCNLGLDAHLEKEIKTEKEMHQPIPFTETIIE 1177 ESQNTLDAKLQDEVKGVKETLPKAVLHDSCNLGLDAHLEKEIKTEKEMHQPIPFTETIIE Sbjct: 1189 ESQNTLDAKLQDEVKGVKETLPKAVLHDSCNLGLDAHLEKEIKTEKEMHQPIPFTETIIE 1248 Query: 1178 SVVSPIMELSHAENVKSTQKTQTDCKCTADSETPSPISGKSLIGDPLNQTRESYIPSNGS 1237 SVVSPIMELSHAENVKSTQKTQTDCKCTADSETPSPISGKSLIGDPLNQTRESYIPSNGS Sbjct: 1249 SVVSPIMELSHAENVKSTQKTQTDCKCTADSETPSPISGKSLIGDPLNQTRESYIPSNGS 1308 Query: 1238 DTREMGYCFAEEKTEIPKDLPATSPETFNYCTPVLSCSKVMKKRVTFALTTSTAKPKCVN 1297 DTREMGYCFAEEKTEIPKDLPATSPETFNYCTPVLSCSKVMKKRVTFALTTSTAKPKCVN Sbjct: 1309 DTREMGYCFAEEKTEIPKDLPATSPETFNYCTPVLSCSKVMKKRVTFALTTSTAKPKCVN 1368 Query: 1298 TKAVKPSISETVSVTSHRKKSELDFKTKFKKINQTKGLVPECLNTLCSPMHSRLQREFCL 1357 TKAVKPSISETVSVTSHRKKSELDFKTKFKKINQTKGLVPECLNTLCSPMHSRLQREFCL Sbjct: 1369 TKAVKPSISETVSVTSHRKKSELDFKTKFKKINQTKGLVPECLNTLCSPMHSRLQREFCL 1428 Query: 1358 PASQLKQGETADKTYTDVFAKNSISHDREEKLQDGKEEEHKVLLEAAPQLSQHLGSEAGQ 1417 PASQLKQGETADKTYTDVFAKNSISHDREEKLQDGKEEEHKVLLEAAPQLSQHLGSEAGQ Sbjct: 1429 PASQLKQGETADKTYTDVFAKNSISHDREEKLQDGKEEEHKVLLEAAPQLSQHLGSEAGQ 1488 Query: 1418 MKEIHLESDPVLNCLTLELHINGQRLQHQTGFEQTTLETSLQMGPLEAEELQKANETEND 1477 MKEIHLESDPVLNCLTLELHINGQRLQHQTGFEQTTLETSLQMGPLEAEELQKANETEND Sbjct: 1489 MKEIHLESDPVLNCLTLELHINGQRLQHQTGFEQTTLETSLQMGPLEAEELQKANETEND 1548 Query: 1478 IKVLGGPKIPPPKALQALENSDGLILNAYQKDNELVKSDEELNQPGSTNIQVQPQTHFTQ 1537 IKVLGGPKIPPPKALQALENSDGLILNAYQKDNELVKSDEELNQPGSTNIQVQPQTHFTQ Sbjct: 1549 IKVLGGPKIPPPKALQALENSDGLILNAYQKDNELVKSDEELNQPGSTNIQVQPQTHFTQ 1608 Query: 1538 TILKSTSCPTLDQFPFEKVESHVRFSPLKSGEAKVDEIIFYAREGGISSDSSHQKEQAGG 1597 TILKSTSCPTLDQFPFEKVESHVRFSPLKSGEAKVDEIIFYAREGGISSDSSHQKEQAGG Sbjct: 1609 TILKSTSCPTLDQFPFEKVESHVRFSPLKSGEAKVDEIIFYAREGGISSDSSHQKEQAGG 1668 Query: 1598 TEKKETAIFGSCMPALSTPKTTRNLKQFSDMKTLVNPKCGIIKAKKPSISYMLNIRAGAG 1657 TEKKETAIFGSCMPALSTPKTTRNLKQFSDMKTLVNPKCGIIKAKKPSISYMLNIRAGAG Sbjct: 1669 TEKKETAIFGSCMPALSTPKTTRNLKQFSDMKTLVNPKCGIIKAKKPSISYMLNIRAGAG 1728 Query: 1658 PKRRKELSCNLTTKMKELHQGKKGVDETYAFLTMTPDINKYSKVETEKDTLREKRLSSTQ 1717 PKRRKELSCNLTTKMKELHQGKKGVDETYAFLTMTPDINKYSKVETEKDTLREKRLSSTQ Sbjct: 1729 PKRRKELSCNLTTKMKELHQGKKGVDETYAFLTMTPDINKYSKVETEKDTLREKRLSSTQ 1788 Query: 1718 VKQDTSPHEDSITSRDIKETLLQDEEQEERKQEPLLKVIPQHLQHFMFRSGQGKDLDFHK 1777 VKQDTSPHEDSITSRDIKETLLQDEEQEERKQE LLKVIPQHLQHFMFRSGQGKDLDFHK Sbjct: 1789 VKQDTSPHEDSITSRDIKETLLQDEEQEERKQEALLKVIPQHLQHFMFRSGQGKDLDFHK 1848 Query: 1778 LENQGSRKILFVTKQDVPQQLQPAEPIQREETKKCLQTQNGTICTVNSKLLPLKSEDSVN 1837 LENQGSRKILFVTKQDVPQQLQPAEPIQREETKKCLQTQNGTICTVNSKLLPLKSEDSVN Sbjct: 1849 LENQGSRKILFVTKQDVPQQLQPAEPIQREETKKCLQTQNGTICTVNSKLLPLKSEDSVN 1908 Query: 1838 GEVLTGAIKRGVPTDRKCMGEQHNSGKGEKAEFNKDLQATVLELQKSPHGGEAQKANLTD 1897 GEVLTGAIKRGVPTDRKCMGEQHNSGKGEKAEFNKDLQATVLELQKSPHGGEAQKANLTD Sbjct: 1909 GEVLTGAIKRGVPTDRKCMGEQHNSGKGEKAEFNKDLQATVLELQKSPHGGEAQKANLTD 1968 Query: 1898 MESGSSNAMNMNVQHEREDKNIQKMLTESVPCYSQHLRFSTHQMKDPDPCKSGSEPKSPE 1957 MESGSSNAMNMNVQHEREDKNIQKMLTESVPCYSQHLRFSTHQMKDPDPCKSGSEPKSPE Sbjct: 1969 MESGSSNAMNMNVQHEREDKNIQKMLTESVPCYSQHLRFSTHQMKDPDPCKSGSEPKSPE 2028 Query: 1958 GRSWNLSHIVQKTKQETHFRETVLEPISGYMMKQSPHMQEGIKCMEGLKTSFPKTGKSKI 2017 GRSWNLSHIVQKTKQETHFRETVLEPISGYMMKQSPHMQEGIKCMEGLKTSFPKTGKSKI Sbjct: 2029 GRSWNLSHIVQKTKQETHFRETVLEPISGYMMKQSPHMQEGIKCMEGLKTSFPKTGKSKI 2088 Query: 2018 GSIPRDTPWDENPRRKWDSSISQKTAWNQKNLQTVLKPLDFSSLMSSEYESRSYTLEFIG 2077 GSIPRDTPWDENPRRKWDSSIS+KTAWNQKNLQTVLKPLDFSSLMSSEYESRSYTLEFIG Sbjct: 2089 GSIPRDTPWDENPRRKWDSSISEKTAWNQKNLQTVLKPLDFSSLMSSEYESRSYTLEFIG 2148 Query: 2078 KKSMSPKCVTLKAKQLRILQLFNIIRYSTENHRKKKQHRFKYKMKGKQWYTSIGEALLSA 2137 KKSMSPKCVTLKAKQLRILQLFNIIRYSTENHRKKKQHRFKYKMKGKQWYTSIGEALLSA Sbjct: 2149 KKSMSPKCVTLKAKQLRILQLFNIIRYSTENHRKKKQHRFKYKMKGKQWYTSIGEALLSA 2208 Query: 2138 TEYAKSTTSKSMIDKLLYNTAARCILSNRTRRQNLDGHITEEKEEVQENVAAIFLGLLDF 2197 TEYAKSTTSKSMIDKLLYNTAARCILSNRTRRQNLDGHITEEKEEVQENVAAIFLGLLDF Sbjct: 2209 TEYAKSTTSKSMIDKLLYNTAARCILSNRTRRQNLDGHITEEKEEVQENVAAIFLGLLDF 2268 Query: 2198 FMPVLSDSKNQRNTAQLSEKEIIFNAKCLTMKEKKSSISQIHKINRESTRKHRKKCKSYL 2257 FMPVLSDSKNQRNTAQLSEKEIIFNAKCLTMKEKKSSISQIHKINRESTRKHRKKCKSYL Sbjct: 2269 FMPVLSDSKNQRNTAQLSEKEIIFNAKCLTMKEKKSSISQIHKINRESTRKHRKKCKSYL 2328 Query: 2258 KTVSNRKCQENHGHITEEEEEVQENSPATFLGPLDFFMPVLSDSKNQINTIQLSERKIIL 2317 KTVSNRKCQENHGHITEEEEEVQENSPATFLGPLDFFMPVLSDSKNQINTIQLSERKIIL Sbjct: 2329 KTVSNRKCQENHGHITEEEEEVQENSPATFLGPLDFFMPVLSDSKNQINTIQLSERKIIL 2388 Query: 2318 NPKCLTMKEKKPPISQIHKISRQFTTKHRKKLESNLKTKLKAMWQGENVADTFPNTTSFT 2377 NPKCLTMKEKKPPISQIHKIS QFTTKHRKKLESNLKTKLKAMWQGENVADTFPNTTSFT Sbjct: 2389 NPKCLTMKEKKPPISQIHKISGQFTTKHRKKLESNLKTKLKAMWQGENVADTFPNTTSFT 2448 Query: 2378 PDSSDIKRQSGFQTEIDMRISGLSHTQPTQIESLAEGIARYSDPIDKRRTSNLVKGAKLH 2437 PDSSDIKRQSGFQTEIDMRISGLSHTQPTQIESLAEGIARYSDPIDKRRTSNLVKGAKLH Sbjct: 2449 PDSSDIKRQSGFQTEIDMRISGLSHTQPTQIESLAEGIARYSDPIDKRRTSNLVKGAKLH 2508 Query: 2438 DRESGEEKQEHLTEMDPFYAENFMANTYLRKDRHLGKSEDVLLGETFFSKSQIYKGNSEK 2497 DRESGEEKQEHLTEMDPFYAENFMANTYLRKDRHLGKSEDVLLGETFFSKSQIYKGNSEK Sbjct: 2509 DRESGEEKQEHLTEMDPFYAENFMANTYLRKDRHLGKSEDVLLGETFFSKSQIYKGNSEK 2568 Query: 2498 NVKIEKNKNGKESLKVGLARMEKSDNCAELSEATDDAISNKYDKQNIGHSVLKENAFCNL 2557 NVKIEKNKNGKESLKVGLARMEKSDNCAELSEATDDAISNKYDKQNIGHSVLKENAFCNL Sbjct: 2569 NVKIEKNKNGKESLKVGLARMEKSDNCAELSEATDDAISNKYDKQNIGHSVLKENAFCNL 2628 Query: 2558 AAIVPDSVGRHSPASEEMKRQNGRLKMADRSSPQGRPLQAKQSAVSQSPDTAGYAVVSNN 2617 AAIVPDSVGRHSPASEEMKRQNGRLKMADRSSPQGRPLQAKQSAVSQSPDTAGYAVVSNN Sbjct: 2629 AAIVPDSVGRHSPASEEMKRQNGRLKMADRSSPQGRPLQAKQSAVSQSPDTAGYAVVSNN 2688 Query: 2618 KEQKQNFKAQKTEAEVDLIDQEAKINVAEEFNPESVFFSKIHPLQIENKKEFKTADWKTR 2677 KEQKQNFKAQKTEAEVDLIDQEAKINVAEEFNPESVFFSKIHPLQIENKKEFKTADWKTR Sbjct: 2689 KEQKQNFKAQKTEAEVDLIDQEAKINVAEEFNPESVFFSKIHPLQIENKKEFKTADWKTR 2748 Query: 2678 ADPKTFALPKKQQELCVSGTIWSYPNPYTSISPKIIRHKDKAKTADVESTMHTKQIKLKA 2737 ADPKTFALPKKQQELCVSGTIWSYPNPYTSISPKIIRHKDKAKTADVESTMHTKQIKLKA Sbjct: 2749 ADPKTFALPKKQQELCVSGTIWSYPNPYTSISPKIIRHKDKAKTADVESTMHTKQIKLKA 2808 Query: 2738 KRIPVSQLLEYGTASNKKELRGNIQQQKSFQLSKNAVHRVLKAVYDSGYCVSSIKKLTEV 2797 KRI VSQLLEYGTASNKKELRGNIQQQKSFQLSKNAVHRVLKAVYDSGYCVSSIKKLTEV Sbjct: 2809 KRITVSQLLEYGTASNKKELRGNIQQQKSFQLSKNAVHRVLKAVYDSGYCVSSIKKLTEV 2868 Query: 2798 KMEKDKPKDRTCILPQPKLEKPLKEMQRSLSGCTDMSSILRKQEQDIREKEQKHQSISED 2857 KMEKDKPKDRTCILPQPKLEKPLKEMQRSLSGCTDMSSILRKQEQDIREKEQKHQSISED Sbjct: 2869 KMEKDKPKDRTCILPQPKLEKPLKEMQRSLSGCTDMSSILRKQEQDIREKEQKHQSISED 2928 Query: 2858 ISQYYIGPLRISSQQINYSSFDAPRIRTDEELEFLIAQRAKEKDVGIAKHSVSIPWEREG 2917 ISQYYIGPLRISSQQINYSSFDAPRIRTDEELEFLIAQRAKEKDVGIAKHSVSIPWEREG Sbjct: 2929 ISQYYIGPLRISSQQINYSSFDAPRIRTDEELEFLIAQRAKEKDVGIAKHSVSIPWEREG 2988 Query: 2918 SKRLDIPLNSKGQNIFFTELDTSQQKICQEQELLKQEDISMTNLGSMACPIMEPLHLENT 2977 SKRLDIPLNSKGQNIFFTELDTSQQK CQEQELLKQEDISMTNLGSMACPIMEPLHLENT Sbjct: 2989 SKRLDIPLNSKGQNIFFTELDTSQQKTCQEQELLKQEDISMTNLGSMACPIMEPLHLENT 3048 Query: 2978 GKVTEEEDVYINRKISSHVLGKEGLKETDIFVGSKGQKFLCTNSEVQHKVPAEQKEQVNP 3037 GKVTEEEDVYINRKISSHVLGKEGLKETDIFVGSKGQKFLCTNSEVQHKVPAEQKEQVNP Sbjct: 3049 GKVTEEEDVYINRKISSHVLGKEGLKETDIFVGSKGQKFLCTNSEVQHKVPAEQKEQVNP 3108 Query: 3038 DHVPESILDSESFLSKDPLHLKQAVNTARKENVTISESFNENLWGKEQSKLDITLKSNRQ 3097 DHVPESILDSESFLSKDPLHLKQAVNTARKENVTISESFNENLWGKEQSKLDITLKSNRQ Sbjct: 3109 DHVPESILDSESFLSKDPLHLKQAVNTARKENVTISESFNENLWGKEQSKLDITLKSNRQ 3168 Query: 3098 KMDFSKKLRMKHLSNYYQNKENILESVLPCILHQLYIENPKKEGSAEEIMSSKVLSPMVE 3157 KMDFSKKLRMKHLSNYYQNKENILESVLPCILHQLYIENPKKEGSAEEIMSSKVLSPMVE Sbjct: 3169 KMDFSKKLRMKHLSNYYQNKENILESVLPCILHQLYIENPKKEGSAEEIMSSKVLSPMVE 3228 Query: 3158 KASHEVGIPVDQPPCSEGIHLNIKGRKEHPQESTHEAFPASVSHSLMDVLQIKSPKVKKA 3217 KASHEVGIPVDQPPCSEGIHLNIKGRKEHPQESTHEAFPASVSHSLMDVLQIKSPKVKKA Sbjct: 3229 KASHEVGIPVDQPPCSEGIHLNIKGRKEHPQESTHEAFPASVSHSLMDVLQIKSPKVKKA 3288 Query: 3218 LKAINSLGYLTSNTKGIGLLFPRQAEKEEKYTYKALPKPASHSKTDLFQFNASMQQEKLD 3277 LKAINSLGYLTSNTKGIGLLFPRQAEKEEKYTYKALPKPASHSKTDLFQFNASMQQEKLD Sbjct: 3289 LKAINSLGYLTSNTKGIGLLFPRQAEKEEKYTYKALPKPASHSKTDLFQFNASMQQEKLD 3348 Query: 3278 AMDIPHYDYLTSQTREAVKQMDVIVGYTQNSKKRQDLLKTGQKWQYLPISYENFWEHISC 3337 AMDIPHYDYLTSQTREAVKQMDVIVGYTQNSKKRQDLLKTGQKWQYLPISYENFWEHISC Sbjct: 3349 AMDIPHYDYLTSQTREAVKQMDVIVGYTQNSKKRQDLLKTGQKWQYLPISYENFWEHISC 3408 Query: 3338 PQKYPCLLQHLMPQEKEALSEGGNLSSRTPGLDLFSADQLSTITKNRLEWIVPLISPRQM 3397 PQKYPCLLQHLMPQEKEALSEGGNLSSRTPGLDLFSADQLSTITKNRLEWIVPLISPRQM Sbjct: 3409 PQKYPCLLQHLMPQEKEALSEGGNLSSRTPGLDLFSADQLSTITKNRLEWIVPLISPRQM 3468 Query: 3398 KKQDSMLPLGSYHKTIKYASLLFPKGMKSSDGVQVFDLISNNSSPKLRLGKKIETQKANE 3457 KKQDSMLPLGSYHKTIKYASLLFPKGMKSSDGVQVFDLISNNSSPKLRLGKKIETQKANE Sbjct: 3469 KKQDSMLPLGSYHKTIKYASLLFPKGMKSSDGVQVFDLISNNSSPKLRLGKKIETQKANE 3528 Query: 3458 KVQKEVCLPITLHSLSASMPILQESKGQKDSVEQVIRKGVICHKRRTSKWKKSVFSHILN 3517 KVQKEVCLPITLHSLSASMPILQESKGQKDSVEQVIRKGVICHKRRTSKWKKSVFSHILN Sbjct: 3529 KVQKEVCLPITLHSLSASMPILQESKGQKDSVEQVIRKGVICHKRRTSKWKKSVFSHILN 3588 Query: 3518 TSDCGASSNRLEMQWNMTDKMVNVKHRMSEIDLVAAKICESILSLPHFKLNKETIDGVIS 3577 TSDCGASSNRLEMQWNMTDKMVNVKHRMSEIDLVAAKICESILSLPHFKLNKETIDGVIS Sbjct: 3589 TSDCGASSNRLEMQWNMTDKMVNVKHRMSEIDLVAAKICESILSLPHFKLNKETIDGVIS 3648 Query: 3578 SNVKSTKQHISQGKNDRVKAMDMKRIKSPNIILKPRKSSLSHILSIKEFPLLLDIIKQEG 3637 SNVKSTKQHISQGKNDRVKAMDMKRIKSPNIILKPRKSSLSHILSIKEFPLLLDIIKQEG Sbjct: 3649 SNVKSTKQHISQGKNDRVKAMDMKRIKSPNIILKPRKSSLSHILSIKEFPLLLDIIKQEG 3708 Query: 3638 KMQEGKGKSSMKLTNLCTSLPSLSHSNSNSRTKAGKDKSGTLKGCLPPLKLQASSNARRV 3697 KMQEGKGKSSMKLTNLCTSLPSLSHSNSNSRTKAGKDKSGTLKGCLPPLKLQASSNARRV Sbjct: 3709 KMQEGKGKSSMKLTNLCTSLPSLSHSNSNSRTKAGKDKSGTLKGCLPPLKLQASSNARRV 3768 Query: 3698 SSAESINRDSLSNVIESKCFPQKKKEDRENIVDVKDIMGLKCITLKGKKSLFRHLLHGKE 3757 SSAESINRDSLSNVIESKCFPQKKKEDRENIVDVKD+MGLKCITLKGKKSLFRHLLHGKE Sbjct: 3769 SSAESINRDSLSNVIESKCFPQKKKEDRENIVDVKDVMGLKCITLKGKKSLFRHLLHGKE 3828 Query: 3758 PQRSNKKLEKMTQEDESNLNVVQNKLCASILSPPHLEWNPRIKEVYMRGITRFCLSSSTQ 3817 PQRSNKKLEKMTQEDESNLNVVQNKLCASILSPPHLEWNPRIKEVYMRGITRFCLSSSTQ Sbjct: 3829 PQRSNKKLEKMTQEDESNLNVVQNKLCASILSPPHLEWNPRIKEVYMRGITRFCLSSSTQ 3888 Query: 3818 QELSDTMEKCEQPIDDSLSSIEKAKHMPQKDKDRVEKALEKIMHSKRIALEVKQPSIFQE 3877 QELSDTMEKCEQPIDDSLSSIEKAKHMPQKDKDRVEKALEKIMHSKRIALEVKQPSIFQE Sbjct: 3889 QELSDTMEKCEQPIDDSLSSIEKAKHMPQKDKDRVEKALEKIMHSKRIALEVKQPSIFQE 3948 Query: 3878 LELNIKEKGGKIQEDKEVEIWSKPFASISFLPYSKVGTIEGEEAMRIKMRSSFSQPNLQE 3937 LELNIKEKGGKIQEDKEVEIWSKPFASISFLPYSKVGTIEGEEAMRIKMRSSFSQPNLQE Sbjct: 3949 LELNIKEKGGKIQEDKEVEIWSKPFASISFLPYSKVGTIEGEEAMRIKMRSSFSQPNLQE 4008 Query: 3938 SSDTEKTAYEKCISDNISNSVKKALESILQKEQRQKMEKIRALKKMKSSISQGIQLDIKE 3997 SSDTEKTAYEKCISDNISNSVKKALESILQKEQRQKMEKIRALKKMKSSISQGIQLDIKE Sbjct: 4009 SSDTEKTAYEKCISDNISNSVKKALESILQKEQRQKMEKIRALKKMKSSISQGIQLDIKE 4068 Query: 3998 QEKRIEHIKGEPSVLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEA 4057 QEKRIEHIKGEPSVLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEA Sbjct: 4069 QEKRIEHIKGEPSVLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEA 4128 Query: 4058 GEKADGVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPL 4117 GEKADGVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPL Sbjct: 4129 GEKADGVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPL 4188 Query: 4118 NTKEPGKMDQEAQEQGKEDREG------------------------------EEQGKEDR 4147 NTKEPGKMDQEAQEQGKEDREG EEQ K D Sbjct: 4189 NTKEPGKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADG 4248 Query: 4148 RGAGQEKVDREDKEQGK----------------MDHEVEEQQKADGV---GI-------- 4180 G Q K+D + EQ + +D +E ++ G+ GI Sbjct: 4249 VGIEQGKMDGDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKS 4308 Query: 4181 -EQGKM------DGDKNEQERVLFLYLP----------SNSSLTHYILDTRIEGEE--DQ 4221 E GK +GD + + Y+ + L H D ++G++ Q Sbjct: 4309 SETGKKANGVPSEGDSASEVQKAKDYMQQKEEDEVKISAEKDLMHPE-DKDLKGKKALSQ 4367 Query: 4222 QGIIRPGILQPRHQKSSETGKKANGVPSEG--DSASEVQKAKDYMQQKEED----ESKQE 4275 + P R + E GK+ +G D +E Q+ D + ++E +SKQE Sbjct: 4368 NLPLNPKEPGKRDGEGQEQGKEDGEGEEQGNRDGETEEQQQADGVGTEQEKRDGHKSKQE 4427 Query: 4276 TVLFLHLPSESSLTCYELNTRKEGEEDLQGIIKSATLQLRQQKSFDAGKIAHTKSFGVDS 4335 TVLFLHLPSESSLTCYELNTRKEGEEDLQGIIKSATLQLRQQKSFDAGKIAHTKSFGVDS Sbjct: 4428 TVLFLHLPSESSLTCYELNTRKEGEEDLQGIIKSATLQLRQQKSFDAGKIAHTKSFGVDS 4487 Query: 4336 SNDVKTVQEYKPQKEVDRGKTVSVDYIMQPEGTIFEAEQLSLPHTLNIPGSSGSKTREVL 4395 SNDVKTVQEYKPQKEVDRGKTVSVDYIMQPEGTIFEAEQLSLPHTLNIPGSSGSKTREVL Sbjct: 4488 SNDVKTVQEYKPQKEVDRGKTVSVDYIMQPEGTIFEAEQLSLPHTLNIPGSSGSKTREVL 4547 Query: 4396 TNIKEKLRHVQERKSELDVFLTIPSLSHCKLDKRTAGKKEEQGVTRSFLPPSWHMESSDT 4455 TNIKEKLRHVQERKSELDVFLTIPSLSHCKLDKRTAGKKEEQGVTRSFLPPSWHMESSDT Sbjct: 4548 TNIKEKLRHVQERKSELDVFLTIPSLSHCKLDKRTAGKKEEQGVTRSFLPPSWHMESSDT 4607 Query: 4456 GKLKYTLSYLNDITGDSNRTKYMAQIQKDKANISEKSVMHPEYIAVKAEKSPLSHILKTK 4515 GKLKYTLSYLNDITGDSNRTKYMAQIQKDKANISEKSVMHPEYIAVKAEKSPLSHILKTK Sbjct: 4608 GKLKYTLSYLNDITGDSNRTKYMAQIQKDKANISEKSVMHPEYIAVKAEKSPLSHILKTK 4667 Query: 4516 ELQVNISQQGEKAQEGEVEIVVLLSKTCPFVTSSAFLELDSIKEEEGEPRITRSFMPHLE 4575 ELQVNISQQGEKAQEGEVEIVVLLSKTCPFVTSSAFLELDSIKEEEGEPRITRSFMPHLE Sbjct: 4668 ELQVNISQQGEKAQEGEVEIVVLLSKTCPFVTSSAFLELDSIKEEEGEPRITRSFMPHLE 4727 Query: 4576 IQESLPSRQTAPTKPTESLVKKEKQLLPQKEDRVQTVSMHGLMHPNGAVFKAKTSAPPQV 4635 IQESLPSRQTAPTKPTESLVKKEKQLLPQKEDRVQTVSMHGLMHPNGAVFKAKTSAPPQV Sbjct: 4728 IQESLPSRQTAPTKPTESLVKKEKQLLPQKEDRVQTVSMHGLMHPNGAVFKAKTSAPPQV 4787 Query: 4636 FSITEHSPLSKRKEPQWGMKERAGQKQDRTGRPHVILTKTHPFMPSLSHHRFSPSQPKLP 4695 FSITEHSPLSKRKEPQWGMKERAGQKQDRTGRPHVILTKTHPFMPSLSHHRFSPSQPKLP Sbjct: 4788 FSITEHSPLSKRKEPQWGMKERAGQKQDRTGRPHVILTKTHPFMPSLSHHRFSPSQPKLP 4847 Query: 4696 ISSGAGKSRLANSNEGISSHKVILKANQQMPYKEAKDRVKIEGREGRILPKRIHLRAEAL 4755 ISSGAGKSRLANSNEGISSHKVILKANQQMPYKEAKDRVKIEGREGRILPKRIHLRAEAL Sbjct: 4848 ISSGAGKSRLANSNEGISSHKVILKANQQMPYKEAKDRVKIEGREGRILPKRIHLRAEAL 4907 Query: 4756 PLALLCNGKNYSLHIEEQGEGVQESKKEPGVVPRKPASFPPPPFYLNCDTRRNEKEGTLG 4815 PLALLCNGKNYSLHIEEQGEGVQESKKEPGVVPRK ASFPPPPFYLNCDTRRNEKEGTLG Sbjct: 4908 PLALLCNGKNYSLHIEEQGEGVQESKKEPGVVPRKSASFPPPPFYLNCDTRRNEKEGTLG 4967 Query: 4816 KTQFSFPPLKIQDSSDSGKKAYTESLHGYTLSNSKGPVQPTAQGEEKGGLRIDMEDKMLP 4875 KTQFSFPPLKIQDSSDSGKKAYTESLHGYTLSNSKGPVQPTAQGEEKGGLRIDMEDKMLP Sbjct: 4968 KTQFSFPPLKIQDSSDSGKKAYTESLHGYTLSNSKGPVQPTAQGEEKGGLRIDMEDKMLP 5027 Query: 4876 KCTDLKAKQLLLSDILNTKKLQWKSKEQKRKIQEDKNKQVKGLPSINTSLLTPPYLKFDT 4935 KCTDLKAKQLLLSDILNTKKLQWKSKEQKRKIQEDKNKQVKGLPSINTSLLTPPYLKFDT Sbjct: 5028 KCTDLKAKQLLLSDILNTKKLQWKSKEQKRKIQEDKNKQVKGLPSINTSLLTPPYLKFDT 5087 Query: 4936 TEGQENVIRIAKVSLPQSRSKESSDAGRIACPEATHGELSSDVKQLKAHLLQKEEKDREK 4995 TEGQENVIRIAKVSLPQSRSKESSDAGRIACPEATHGELSSDVKQLKAHLLQKEEKDREK Sbjct: 5088 TEGQENVIRIAKVSLPQSRSKESSDAGRIACPEATHGELSSDVKQLKAHLLQKEEKDREK 5147 Query: 4996 VADMTSVLDPNKMYLKAKKSPVLHTHSFSDLQWKTREQEEEKVQKVKSGPGVMLSKSPSR 5055 VADMTSVLDPNKMYLKAKKSPVLHTHSFSDLQWKTREQEEEKVQKVKSGPGVMLSKSPSR Sbjct: 5148 VADMTSVLDPNKMYLKAKKSPVLHTHSFSDLQWKTREQEEEKVQKVKSGPGVMLSKSPSR 5207 Query: 5056 SSPLHLNVNTGFQEESIPILTRPSFPLVKLQVSPDTEGGTCIRPIAGDILIYLQKGKHVS 5115 SSPLHLNVNTGFQEESIPILTRPSFPLVKLQVSPDTEGGTCIRPIAGDILIYLQKGKHVS Sbjct: 5208 SSPLHLNVNTGFQEESIPILTRPSFPLVKLQVSPDTEGGTCIRPIAGDILIYLQKGKHVS 5267 Query: 5116 QNKEEDDVQIVSILIFPKHQEEKVQECEGEPGVVLTKSTSLPSLSQLELDKETHLGNEML 5175 QNKEEDDVQIVSILIFPKHQEEKVQECEGEPGVVLTKSTSLPSLSQLELDKETHLGNEML Sbjct: 5268 QNKEEDDVQIVSILIFPKHQEEKVQECEGEPGVVLTKSTSLPSLSQLELDKETHLGNEML 5327 Query: 5176 RLKRPILRRISHIGETVHRESVVGDIPKDVKNEKQHIPQKEERNQKKIIDMRGTDITLKS 5235 RLKRPILRRISHIGETVHRESVVGDIPKDVKNEKQHIPQKEERNQKKIIDMRGTDITLKS Sbjct: 5328 RLKRPILRRISHIGETVHRESVVGDIPKDVKNEKQHIPQKEERNQKKIIDMRGTDITLKS 5387 Query: 5236 KKSPRSCMLHRTELHVNIGGQGRKEHEGQDKPPGMIQRKMCILFSKPLPSNLKLERATHA 5295 KKSPRSCMLHRTELHVNIGGQGRKEHEGQDKPPGMIQRKMCILFSKPLPSNLKLERATHA Sbjct: 5388 KKSPRSCMLHRTELHVNIGGQGRKEHEGQDKPPGMIQRKMCILFSKPLPSNLKLERATHA 5447 Query: 5296 DEERLGGKTSFVLPLMPSALPDTEKTADAEARSGDVRKGKPHRSQKENRHEVKTIDMRFR 5355 DEERLGGKTSFVLPLMPSALPDTEKTADAEARSGDVRKGKPHRSQKENRHEVKTIDMRFR Sbjct: 5448 DEERLGGKTSFVLPLMPSALPDTEKTADAEARSGDVRKGKPHRSQKENRHEVKTIDMRFR 5507 Query: 5356 IHCQEARISPMSHILNAKELVLNINKLEKKVHKDKDEACVVLSRTFLSIPSAPPLYLDSG 5415 IHCQEARISPMSHILNAKELVLNINKLEKKVHKDKDEACVVLSRTFLSIPSAPPLYLDSG Sbjct: 5508 IHCQEARISPMSHILNAKELVLNINKLEKKVHKDKDEACVVLSRTFLSIPSAPPLYLDSG 5567 Query: 5416 NKTDKDTPGITGSSCPQRTLHVPSNTQKITNRDSVEGVDKNVVKQAEQYVPRPEAEQQLT 5475 NKTDKDTPGITGSSCPQRTLHVPSNTQKITNRDSVEGVDKNVVKQAEQYVPRPEAEQQLT Sbjct: 5568 NKTDKDTPGITGSSCPQRTLHVPSNTQKITNRDSVEGVDKNVVKQAEQYVPRPEAEQQLT 5627 Query: 5476 SNFMISVQQRNQPSRVTSEEDLNQLVLNSRDEDIYFTGFGTIRSGKRPEWLFTGKKAQPV 5535 SNFMISVQQRNQPSRV SEEDLNQLVLNSRDEDIYFTGFGTIRSGKRPEWLFTGKKAQPV Sbjct: 5628 SNFMISVQQRNQPSRVRSEEDLNQLVLNSRDEDIYFTGFGTIRSGKRPEWLFTGKKAQPV 5687 Query: 5536 KYKTETLTAFLSYPTMDATKMGGLEEDTEIMDNLNHKISPKASVSLIRKISKELYVTLGT 5595 KYKTETLTAFLSYPTMDATKMGGLEEDTEIMDNLNHKISPKASVSLIRKISKELYVTLGT Sbjct: 5688 KYKTETLTAFLSYPTMDATKMGGLEEDTEIMDNLNHKISPKASVSLIRKISKELYVTLGT 5747 Query: 5596 PASSKGFSVSERYAHQQETSSKVSPELAGSCKFDKPKEDGQSNDRISKMFSPKVLAPQTK 5655 PA+SKGFSVSERYAHQQETSSKVSPELAGSCKFDKPKEDGQSNDRISKMFSPKVLAPQTK Sbjct: 5748 PANSKGFSVSERYAHQQETSSKVSPELAGSCKFDKPKEDGQSNDRISKMFSPKVLAPQTK 5807 Query: 5656 GSLKKISIVTNWNAPQNIEEQDIVMKKQVIRRCEHGHKTRTNTILSKFPLQSGKQKTPSE 5715 GSLKKISIVTNWNAPQNIEEQDIVMKKQVIRRCEHGHKTRTNTILSKFPLQSGKQKTPSE Sbjct: 5808 GSLKKISIVTNWNAPQNIEEQDIVMKKQVIRRCEHGHKTRTNTILSKFPLQSGKQKTPSE 5867 Query: 5716 TDVDKKTTAHLSLQMLPGIHMDMTEIDPAKGGRKQALLISEQEEGVLELLPKSLFPPWTF 5775 TDVDKKTTAHLSLQMLPGIHMDMTEIDPAKGGRKQALLISEQEEGVLE LPKSLFPPWTF Sbjct: 5868 TDVDKKTTAHLSLQMLPGIHMDMTEIDPAKGGRKQALLISEQEEGVLEFLPKSLFPPWTF 5927 Query: 5776 QFQSGDLEEKHQTDANTNINLEQKKLEMDNDSTVNQKEGKLKIGTNRALHLQEEKTEMHK 5835 QFQSGDLEEKHQTDANTNINLEQKKLEMDNDSTVNQKEGKLKIGTNRALHLQEEKTEMHK Sbjct: 5928 QFQSGDLEEKHQTDANTNINLEQKKLEMDNDSTVNQKEGKLKIGTNRALHLQEEKTEMHK 5987 Query: 5836 ARTANLEKERGRMDTSSSAHPHLPSLKAEESQMKTQVITHRENSRLIMQKQKKELEASNA 5895 ARTANLEKERGRMDTSSSAHPHL SLKAEESQMKTQVITHRENSRLIMQKQKKELEASNA Sbjct: 5988 ARTANLEKERGRMDTSSSAHPHLLSLKAEESQMKTQVITHRENSRLIMQKQKKELEASNA 6047 Query: 5896 KQSIQLQKLFQRNVLDSFYSYVPLSPKCKDQKGRLTIRDLKRELSTKYLTMKIQNHPIPQ 5955 KQSIQLQKLFQRNVLDSFYSYVPLSPK KDQKGRLTIRDLKRELSTKYLTMKIQNHPIPQ Sbjct: 6048 KQSIQLQKLFQRNVLDSFYSYVPLSPKRKDQKGRLTIRDLKRELSTKYLTMKIQNHPIPQ 6107 Query: 5956 MLNITGRGTPSNRKKLEYDVKLKNIASWSKDVSGIFIRSLSISIMRSPHTDPKTNLEREK 6015 MLNITGRGTPSNRKKLEYDVKLKNIASWSKDVSGIFIRSLSISIMRSPHTDPKTNLEREK Sbjct: 6108 MLNITGRGTPSNRKKLEYDVKLKNIASWSKDVSGIFIRSLSISIMRSPHTDPKTNLEREK 6167 Query: 6016 RICLPKFQEKSPNTSEMSKRDTLTIVKGEQNFTNTVPQDPQPFAVDKQQMQKLPNVKSEA 6075 RICLPKFQEKSPNTSEMSKRDTLTIVKGEQNFTNTVPQDPQPFAVDKQQMQKLPNVKSEA Sbjct: 6168 RICLPKFQEKSPNTSEMSKRDTLTIVKGEQNFTNTVPQDPQPFAVDKQQMQKLPNVKSEA 6227 Query: 6076 NLRSEMNKKYLKAQTKERIVPEHDVSRIIKKPDLRIIEQEEKILKRILTPTECPSMLEDP 6135 NLRSEMNKKYLKAQTKERIVPEHDVSRIIKKPDLRIIEQEEKILKRILTPTECPSMLEDP Sbjct: 6228 NLRSEMNKKYLKAQTKERIVPEHDVSRIIKKPDLRIIEQEEKILKRILTPTECPSMLEDP 6287 Query: 6136 KLPKQRDQSEPVWDMTTQKVQQQKAFPGTVPIPPQVKSSEVKIVADSTNAEHLLPICEAT 6195 KLPKQRDQSEPVWDMTTQKVQQQKAFPGTVPIPPQVKSSEVKIVADSTNAEHLLPICEAT Sbjct: 6288 KLPKQRDQSEPVWDMTTQKVQQQKAFPGTVPIPPQVKSSEVKIVADSTNAEHLLPICEAT 6347 Query: 6196 KAISESQVKNMIQDKVSSDKLDNIQAYKPDDLKSPPFPEGPDTISTAIYPKTQHKSLLEQ 6255 KAISESQVKNMIQDKVSSDKLDNIQAYKPDDLKSPPFPEGPDTISTAIYPKTQHKSLLEQ Sbjct: 6348 KAISESQVKNMIQDKVSSDKLDNIQAYKPDDLKSPPFPEGPDTISTAIYPKTQHKSLLEQ 6407 Query: 6256 FTPKEKNKLTSHLESKALEIQLNLIPEMARKSLQMFNFYPKGTISKDNSWRFYSRHKTMN 6315 FTPKEKNKLTSHLESKALEIQLNLIPEMARKSLQMFNFYPKGTISKDNSWRFYSRHKTMN Sbjct: 6408 FTPKEKNKLTSHLESKALEIQLNLIPEMARKSLQMFNFYPKGTISKDNSWRFYSRHKTMN 6467 Query: 6316 FMSLEGTDTIEPNSKHKHQKDSPLASNMKTLIVDVSSDSEETITKLQSINKLENGTSAVT 6375 FMSLEGTDTIEPNSKHKHQKDSPLASNMKTLIVDVSSDSEETITKLQSINKLENGTSAVT Sbjct: 6468 FMSLEGTDTIEPNSKHKHQKDSPLASNMKTLIVDVSSDSEETITKLQSINKLENGTSAVT 6527 Query: 6376 SASEMLLPHTLQNHSVKEKGKLLMHFSVKTLEIQMKAFPRIVRESYAMTSAHERKKPLSN 6435 SASEMLLPHTLQNHSVKEKGKLLMHFSVKTLEIQMKAFPRIVRESYAMTSAHERKKPLSN Sbjct: 6528 SASEMLLPHTLQNHSVKEKGKLLMHFSVKTLEIQMKAFPRIVRESYAMTSAHERKKPLSN 6587 Query: 6436 CIHPGFTGPKRQNRILLLSEEKSLHQIDLDLQYKYLRFLLGLPVGSTFPKPNVLPKHSKL 6495 CIHPGFTGPKRQNRILLLSEEKSLHQIDLDLQYKYLRFLLGLPVGSTFPKPNVLPKHSKL Sbjct: 6588 CIHPGFTGPKRQNRILLLSEEKSLHQIDLDLQYKYLRFLLGLPVGSTFPKPNVLPKHSKL 6647 Query: 6496 NTIAVCKNVNAGGQSGSLSIDTELLEQHISFKKQSPHENSSLIRKFPQPTLVCASDRDLH 6555 NTIAVCKNVNAGGQSGSLSIDTELLEQHISFKKQSPHENSSLIRKFPQPTLVCASDRDLH Sbjct: 6648 NTIAVCKNVNAGGQSGSLSIDTELLEQHISFKKQSPHENSSLIRKFPQPTLVCASDRDLH 6707 Query: 6556 SPRKKDTQVLSESEFHVTPEKNKQYHVWFQERNTCESVDLRTQRNATGSAVSCETQISED 6615 SPRKKDTQVLSESEFHVTPEKNKQYHVWFQERNTCESVDLRTQRNATGSAVSCETQISED Sbjct: 6708 SPRKKDTQVLSESEFHVTPEKNKQYHVWFQERNTCESVDLRTQRNATGSAVSCETQISED 6767 Query: 6616 FVDIQTDIESPADLDECSCLEVSESEECVFLEANSYLSQESENILFELQTGIPLENVYKI 6675 FVDIQTDIESPADLDECSCLEVSESEECVFLEANSYLSQESENILFELQTGIPLENVYKI Sbjct: 6768 FVDIQTDIESPADLDECSCLEVSESEECVFLEANSYLSQESENILFELQTGIPLENVYKI 6827 Query: 6676 TTDLKSFYSEDSGSHCTRECRKETLIITPPSCKSHKSRKYRSSSKMKSPDWLCHSSSNTA 6735 TTDLKSFYSEDSGSHCTRECRKETLIITPPSCKSHKSRKYRSSSKMKSPDWLCHSSSNTA Sbjct: 6828 TTDLKSFYSEDSGSHCTRECRKETLIITPPSCKSHKSRKYRSSSKMKSPDWLCHSSSNTA 6887 Query: 6736 EIQSRSSSVSFSEEKISWTTKSRTSYSSAPLTESNIKSHLAKNQGKSHRHPESQERKKAR 6795 EIQSRSSSVSFSEEKISWTTKSRTSYSSAPLTESNIKSHLAKNQGKSHRHPESQERKKAR Sbjct: 6888 EIQSRSSSVSFSEEKISWTTKSRTSYSSAPLTESNIKSHLAKNQGKSHRHPESQERKKAR 6947 Query: 6796 SDLFRKNSSHWDHDYSCTHSKGKRDRKKRVYDYESERLDCFQSKHKSASKPHHDDINFYS 6855 SDLFRKNSSHWDHDYSCTHSKGKRDRKKRVYDYESERLDCFQSKHKSASKPHHDDINFYS Sbjct: 6948 SDLFRKNSSHWDHDYSCTHSKGKRDRKKRVYDYESERLDCFQSKHKSASKPHHDDINFYS 7007 Query: 6856 ERKQNRPFFFACVPADSLEVIPKTIRWTIPPETLRKRNFRIPLVAKISSSWNIWSSSKKL 6915 ERKQNRPFFFACVPADSLEVIPKTIRWTIPPETLRKRNFRIPLVAKISSSWNIWSSSKKL Sbjct: 7008 ERKQNRPFFFACVPADSLEVIPKTIRWTIPPETLRKRNFRIPLVAKISSSWNIWSSSKKL 7067 Query: 6916 LGSLSGSLTTVFHS 6929 LGSLSGSLTTVFHS Sbjct: 7068 LGSLSGSLTTVFHS 7081 >gi|71061468 centromere protein E [Homo sapiens] Length = 2701 Score = 68.2 bits (165), Expect = 3e-10 Identities = 349/1865 (18%), Positives = 696/1865 (37%), Gaps = 331/1865 (17%) Query: 3528 LEMQWNMTDKMVNVKHRMSEIDLVAAKICESILSLPHFKLNK-ETIDGVISSNVKSTKQH 3586 ++ Q + + + ++K I+ + +KI E + H + N ET D V K+ Sbjct: 960 IDTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQ 1019 Query: 3587 ISQGKNDRVKAMDMKRIKSPNIILKPRKSSLSHILSIKEFPLLLDIIKQEGKMQEGKGKS 3646 + KN + D+K N I++ ++ S I E +L+ + E + + K Sbjct: 1020 DLEAKNTQTLTADVK----DNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKE 1075 Query: 3647 SMKLTN--------LCTSLPSLSHSNSNSRTKAGKDKSGTLKGCLPPLKLQASSNARRVS 3698 ++++T L L + + A K K G L L + + S Sbjct: 1076 NIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIK-KEGELSRTCDRLA-EVEEKLKEKS 1133 Query: 3699 SAESINRDSLSNVIESKCFPQKKKEDRENIVDVKDIMGLKCITLKGKKS----LFRHLLH 3754 + L NV E QKK + EN+ K+ + K +TL+ ++ L + L Sbjct: 1134 QQLQEKQQQLLNVQEEMSEMQKKINEIENL---KNELKNKELTLEHMETERLELAQKLNE 1190 Query: 3755 GKEPQRSNKKLEKMTQEDESNLNVVQNKLCASILSPPHLEWNPRIKEVYMRGITRFCLSS 3814 E +S K K+ +E + + ++ L I+E+ G+ Sbjct: 1191 NYEEVKSITKERKVLKELQKSFETERDHL------------RGYIREIEATGL------- 1231 Query: 3815 STQQELSDT---MEKCEQPIDDSLSSIEKAKHMPQKDKDRVEKALEKIMHSKRIALEVKQ 3871 T++EL +++ ++ ID+ S+ + +D LEK H+K L+ + Sbjct: 1232 QTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQD-----LEK-SHTK---LQEEI 1282 Query: 3872 PSIFQELEL--NIKEKGGKIQEDKEVEIWSKPFASISFLPYSKVGTIEGEEAMRIKMRSS 3929 P + +E EL N+KE + E+E+ ++ + +++ E R+++ Sbjct: 1283 PVLHEEQELLPNVKEVSETQETMNELELLTEQSTTKDSTTLARI------EMERLRLNEK 1336 Query: 3930 FSQPNLQESSDTEKTAYEKCISDNISNSVKKALESILQKEQRQKMEKIRALKKMKSSISQ 3989 F QES + K+ ++ DN+ ++K+ALE + + E + +++ +S Q Sbjct: 1337 F-----QESQEEIKSLTKE--RDNLK-TIKEALEVKHDQLKEHIRETLAKIQESQSKQEQ 1388 Query: 3990 GIQLDIKEQE-----KRIEHIKGEPSVLLTNACASIPSPSHLQL--DTRREKAEYVTEIT 4042 + + K+ E +E K + S LL + LQ D + A+ ++ Sbjct: 1389 SLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQ 1448 Query: 4043 RYYLPELSHQKSSEAGEKADGVASKGDITIKVQKAKDYMQQKEDD-----EVKISAKKDI 4097 R L E+ +S + E + +K T + K +++++ V +S K+ Sbjct: 1449 R--LQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKETE 1506 Query: 4098 MHPEDKGLKA---------KKALSQDLPLNTKEPGKMDQEAQE--QGKEDREGEEQGKED 4146 + K L+A ++ ++ N K+ ++ ++ E Q KE R+ ++ + Sbjct: 1507 ISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSALQS 1566 Query: 4147 RRGAGQEKVDREDKEQGKMDHEVEEQQKADGVGIE-QGKMDGDKNEQERVLFLYLPSNSS 4205 E +R + Q ++ ++E+++ V Q + D K + ++ S Sbjct: 1567 IESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKENTKEIVAKMKESQEK 1626 Query: 4206 LTHYILDTRIEGEEDQQGIIRPGILQPRHQKSS----------------ETGKKANGVPS 4249 ++ T + +++ I Q QK + E ++ V Sbjct: 1627 EYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIETENIRLTQILHENLEEMRSVTK 1686 Query: 4250 EGDSASEVQKAKDYMQQKEEDESKQETVLFLHLPSESSLTCYELNTRKEGEEDLQGIIKS 4309 E D V++ + + ++ ++ L E + L +E + L+GI+ Sbjct: 1687 ERDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSE 1746 Query: 4310 ATLQLRQQKSFDAGKIAHTKSFGVDSSNDVKTVQEYKPQKEVDRGKTVSVDYIMQPEGTI 4369 T ++ + ++ SND Q+ K Q+E+ ++ ++ + + TI Sbjct: 1747 KTNEISNMQK------------DLEHSNDALKAQDLKIQEEL----RIAHMHLKEQQETI 1790 Query: 4370 FEAEQLSLPHTLNIPGSSGSKTREVLTNIKEKLRHVQERKSELDVFLTIPSLSHCKLDKR 4429 K R +++ +KL ++Q+ S+ KL ++ Sbjct: 1791 -------------------DKLRGIVSEKTDKLSNMQKDLEN----------SNAKLQEK 1821 Query: 4430 TAGKK--EEQGVTRSFLPPSWHMESSDTGKLKYTLSYLNDITGDSNRTKYMAQIQKDKAN 4487 K E Q +T + ++T K + L D + T +++++ + N Sbjct: 1822 IQELKANEHQLITLK-------KDVNETQKKVSEMEQLKKQIKDQSLT--LSKLEIENLN 1872 Query: 4488 ISEKSVMHPEYI-AVKAEKSPLSHILKTKEL---QVNISQQGEKAQEGEVEIVVLLSKTC 4543 +++K + E + +V E+ L + +T +L Q+ S Q KA++ E++ + KT Sbjct: 1873 LAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQEL---KTA 1929 Query: 4544 PFVTSSAFLELDSIKEEEGEPRITRSFMPHLEIQESLPSRQTAPTKPTESLVKKEKQLLP 4603 ++ +D ++E+ E I S +IQ+ L + K + L KKE QLL Sbjct: 1930 RMLSKEHKETVDKLREKISEKTIQIS-----DIQKDLDKSKDELQKKIQELQKKELQLLR 1984 Query: 4604 QKEDRVQTVSMHGLMHPNGAVFKAKTSAPPQV----FSITE--HSPL------SKRKEPQ 4651 KED + M F+A+ + V F +T+ H L +K ++ Sbjct: 1985 VKEDVNMSHKKINEMEQLKKQFEAQNLSMQSVRMDNFQLTKKLHESLEEIRIVAKERDEL 2044 Query: 4652 WGMKERAGQKQDRTGRPHVILTKTHPFMPSLSHHRFSPSQPKLPISSGAGKSRLANS-NE 4710 +KE ++D+ I T +H+ P + L G+ L S E Sbjct: 2045 RRIKESLKMERDQ-----FIATLREMIARDRQNHQVKPEKRLL----SDGQQHLTESLRE 2095 Query: 4711 GISSHKVILKANQQM-PYKEAKDRVKIEGREGRILPKRIHLRAEA---LPL-------AL 4759 S K +LK +M + E +R+ ++ + K + +R +A LP L Sbjct: 2096 KCSRIKELLKRYSEMDDHYECLNRLSLDLEKEIEFQKELSMRVKANLSLPYLQTKHIEKL 2155 Query: 4760 LCNGKNYSLHI------------------EEQGEGVQESKKE--PGVVPRKPASFPPPPF 4799 + S+ EEQ E + + + + V +K Sbjct: 2156 FTANQRCSMEFHRIMKKLKYVLSYVTKIKEEQHESINKFEMDFIDEVEKQKELLIKIQHL 2215 Query: 4800 YLNCDTRRNE--------------KEGTLGKTQFSFPPLKIQ-DSSDSGKKAYTESLHGY 4844 +CD E +E ++ FP +K + S +K T+ L + Sbjct: 2216 QQDCDVPSRELRDLKLNQNMDLHIEEILKDFSESEFPSIKTEFQQVLSNRKEMTQFLEEW 2275 Query: 4845 TLSNSKGPVQPTAQGEEKGGLRIDMEDK--------MLPKCTDLKAKQLLLSDILNTKKL 4896 N++ ++ G +K RI + ++ + T+ + + +S Sbjct: 2276 L--NTRFDIEKLKNGIQKENDRICQVNNFFNNRIIAIMNESTEFEERSATIS-------- 2325 Query: 4897 QWKSKEQKRKIQEDKNKQV-KGLPSINTSLLTPPYLKFDTTEGQENVIRIAKVSLPQSRS 4955 K EQ K ++KN+++ K ++ TSL + + T + + + L + Sbjct: 2326 --KEWEQDLKSLKEKNEKLFKNYQTLKTSLASGAQVNPTTQDNKNPHVTSRATQLTTEKI 2383 Query: 4956 KESSDAGRIACPEATHG-----------ELSSDVKQLKAHLLQKEEKDREKVADMTSVLD 5004 +E ++ A A H E+++D+ + + K EK + VL Sbjct: 2384 RELENSLHEAKESAMHKESKIIKMQKELEVTNDIIAKLQAKVHESNKCLEKTKETIQVLQ 2443 Query: 5005 PNKMYLKAKKSPVLHTHSFSDLQWKTREQEEEKVQKVK------SGPGVMLSKSPSRSSP 5058 +K+ L AK + DL+ K + + EK++ K S + Sbjct: 2444 -DKVALGAKP----YKEEIEDLKMKLVKIDLEKMKNAKEFEKEISATKATVEYQKEVIRL 2498 Query: 5059 LHLNVNTGFQEESIPILTRPSFPLVKLQVSPDTEGGTCIRPIAGDILIYLQKGKHVSQNK 5118 L N+ Q + +++ + P + P T GG I + + K +H+ K Sbjct: 2499 LRENLRRSQQAQDTSVISEHTDP--QPSNKPLTCGGG--SGIVQNTKALILKSEHIRLEK 2554 Query: 5119 EEDDVQIVSILIFPKHQEEKVQECEGEPGVVLTKSTSLPSLSQLELDKETHLGNEMLRLK 5178 E + K Q E++ + + E L HL NE+ K Sbjct: 2555 EISKL---------KQQNEQLIKQKNE-----------------LLSNNQHLSNEVKTWK 2588 Query: 5179 RPILRRISHIGETVHRESVVGDIPKDVKNEKQHIP-QKEERNQKKIIDMRGTDITLKSKK 5237 L+R +H T + +KQ P Q +ERN + + K+ Sbjct: 2589 ERTLKREAHKQVTCENSPKSPKVTGTASKKKQITPSQCKERNLQDPV----------PKE 2638 Query: 5238 SPRSC 5242 SP+SC Sbjct: 2639 SPKSC 2643 Score = 45.1 bits (105), Expect = 0.003 Identities = 201/1052 (19%), Positives = 404/1052 (38%), Gaps = 155/1052 (14%) Query: 3597 AMDMKR----IKSPNIILKPRKSSLSHILSIKEFPLLL--DIIKQEGKMQEGKGKSSMKL 3650 A+D KR ++S N+ LK + L+ E + L ++ + KMQ K Sbjct: 634 ALDAKRESAFLRSENLELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSA 693 Query: 3651 TNLCTSLPSLSHSNSNSRTKAGKDKSGTLKGCLPPLKLQASSNARRVSSAESINRDSLSN 3710 N T L SL + G + L + N E++ R+ + Sbjct: 694 FNEITKLTSLIDGKVPKDLLCNLELEGKITDLQKELNKEVEEN-------EAL-REEVIL 745 Query: 3711 VIESKCFPQKKKEDRENIVDVKDIMGLKCITLKGKKSLFRHLLHGKEPQRSNKKLEKM-- 3768 + E K P + + R+ I D + + I K LF ++H + R LE++ Sbjct: 746 LSELKSLPSEVERLRKEIQDKSEELH---IITSEKDKLFSEVVH--KESRVQGLLEEIGK 800 Query: 3769 TQED----ESNLNVVQNKLCASILSPPHLEWNPRIKEVYMRGITRFCLSSSTQQELSDTM 3824 T++D +SN + H+++ + K V + QE+ + + Sbjct: 801 TKDDLATTQSNYKSTDQEF--QNFKTLHMDFEQKYKMVLEE-------NERMNQEIVN-L 850 Query: 3825 EKCEQPIDDSLSSIE-----KAKHMPQKDKDRVEK----------------ALEKIMHSK 3863 K Q D SL +++ K + + +K ++ E+ L+ + K Sbjct: 851 SKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREK 910 Query: 3864 RIALEVKQPSIFQELELNIKEKGGKIQEDKEVEIWSKPFASISFLPYSKVGTIEGEEAMR 3923 + E Q ++ +E++ +EK Q + ++I S + I+ +E +R Sbjct: 911 TLITEKLQQTL-EEVKTLTQEKDDLKQLQESLQIERDQLKSDIHDTVNM--NIDTQEQLR 967 Query: 3924 IKMRSSFSQPNLQESSDTEKTAYEKCISDNISNSVKKALESILQKEQ-RQKMEKIRALKK 3982 + S L++ +T T K IS+ +S ++ + K++ +QKM I + Sbjct: 968 NALES------LKQHQETINTLKSK-ISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQD 1020 Query: 3983 MKSSISQGIQLDIK-----EQEKRIEHIKGEPSVLLTNACASIPSPSHLQLDTRR--EKA 4035 +++ +Q + D+K EQ+++I + E + L + I L+ D + E Sbjct: 1021 LEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMT 1080 Query: 4036 EYVTEITRYYLPELSHQKSSEAGEKADGVASKGDITIKV-------QKAKDYMQQKEDDE 4088 E R EL Q+ A EK + +G+++ +K K+ QQ ++ + Sbjct: 1081 IENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQ 1140 Query: 4089 VKISAKKDIMHPEDKGLKAKKALSQDLPLNTKEPGKMDQEAQEQGKEDREGEEQGKEDRR 4148 ++ ++ M K + + L +L M+ E E ++ E E+ K + Sbjct: 1141 QQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITK 1200 Query: 4149 GAGQEKVDREDKE--QGKMDHEVEEQQKADGVGIEQGKMDGDKNEQERVLFLYLPSNSSL 4206 + KV +E ++ + + DH ++ + G++ E+ ++ ++L + Sbjct: 1201 ---ERKVLKELQKSFETERDHLRGYIREIEATGLQ-------TKEELKIAHIHLKEHQET 1250 Query: 4207 THYILDTRIEGEEDQQGIIRPGILQPRHQKSSETGKKANGVPSEGDSASEVQKAKDYMQQ 4266 I + R E II L+ H K E + + EV + ++ M + Sbjct: 1251 ---IDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKEVSETQETMNE 1307 Query: 4267 ----KEEDESKQETVLF------LHLPSESSLTCYELNTRKEGEEDLQGIIKSATL---Q 4313 E+ +K T L L L + + E+ + + ++L+ I ++ + Q Sbjct: 1308 LELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQ 1367 Query: 4314 LRQQKSFDAGKIAHTKSFGVDSSNDVKTVQEYKPQKEVDRGKTVSVDYIMQPEGTI---F 4370 L++ KI ++S S N +K+ + K VS +P+ + Sbjct: 1368 LKEHIRETLAKIQESQSKQEQSLN--------MKEKDNETTKIVSEMEQFKPKDSALLRI 1419 Query: 4371 EAEQLSLPHTL------------------NIPGSSGSKTREVLTNIKEKLRHVQERKSEL 4412 E E L L L + S++ ++ NIKE + E + EL Sbjct: 1420 EIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEEL 1479 Query: 4413 DVFLTIPSLSHCKLDKRTAGKKEEQGVTRSFLPPSWHMESSDTGKLKYTLSYLNDITGDS 4472 V +HC L +EQ T + L + + ++ ++ L +ND + Sbjct: 1480 KV-------AHCCL--------KEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNK 1524 Query: 4473 NRTKYMAQIQKDKANISEKSVMHPEYIAVKAEKSPLSHILKTKELQ-VNISQQGEKAQEG 4531 + Y + Q + ISE E K + L++ E + + ++ + +++QE Sbjct: 1525 IQEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQE- 1583 Query: 4532 EVEIVVLLSKTCPFVTSSAFLELDSIKEEEGE 4563 E++I++ + V + +E D +KE E Sbjct: 1584 EIQIMIKEKEEMKRVQEALQIERDQLKENTKE 1615 Score = 43.9 bits (102), Expect = 0.006 Identities = 135/676 (19%), Positives = 265/676 (39%), Gaps = 100/676 (14%) Query: 5780 GDLEEKHQTD---ANTNINLEQKKLEMDNDSTVNQK-EGKLKIGTNRALHLQEEKTEMHK 5835 G LEE +T A T N + E N T++ E K K+ + EE M++ Sbjct: 793 GLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKM-------VLEENERMNQ 845 Query: 5836 ARTANLEKERGRMDTSSSAHPHLPSLKAEESQMKTQVITHRENSRLIMQKQKKELE-ASN 5894 NL KE + D+S A S K +E Q KT+ + R N M++ K++LE + Sbjct: 846 -EIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNE---MEQLKEQLENRDS 901 Query: 5895 AKQSIQLQKLFQRNVLDSFYSYVPLSPKCKDQKGRLTIRDLKRELSTKYLTMKIQNHPIP 5954 Q+++ +K L V + KD ++ L+ L + +K H Sbjct: 902 TLQTVEREKTLITEKLQQTLEEVKTLTQEKDD-----LKQLQESLQIERDQLKSDIHDTV 956 Query: 5955 QMLNITGRGTPSNRKKLEYDVKLKNIASWSKDVSGIFIRSLSISIMRSPHTDPKTNLERE 6014 M NI + N L+++ + ++ + + +S + R+ H + T ++ Sbjct: 957 NM-NIDTQEQLRN--------ALESLKQHQETINTLKSK-ISEEVSRNLHMEENTGETKD 1006 Query: 6015 KRICLPKFQEKSPNTSEMSKRDTLTIVKGEQNFTNTVPQDPQPFAVDKQQMQKLPNVKSE 6074 +FQ+K + K+D E T T+ D + + +QQ +K+ ++ E Sbjct: 1007 ------EFQQKMVGIDK--KQDL------EAKNTQTLTADVKDNEIIEQQ-RKIFSLIQE 1051 Query: 6075 ANLRSEM------NKKYLKAQTKERIVPEHDVSRIIKKPDLRIIEQEEKILKRILTPTEC 6128 N +M K+ LK KE I I + +LR++ E K + I+ + Sbjct: 1052 KNELQQMLESVIAEKEQLKTDLKENI-----EMTIENQEELRLLGDELKKQQEIVAQEKN 1106 Query: 6129 PSMLEDPKLPKQRDQSEPVWDMTTQKVQQQKAFPGTVPIPPQVKSSEVKIVADSTNAEHL 6188 ++ ++ +L + D+ V + +K QQ Q K ++ V + +E Sbjct: 1107 HAIKKEGELSRTCDRLAEVEEKLKEKSQQL-----------QEKQQQLLNVQEEM-SEMQ 1154 Query: 6189 LPICEATKAISESQVKNMIQDKVSSDKLDNIQAYKPDDLKSPPFPEGPDTISTAIYPKTQ 6248 I E +E + K + + + +++L+ Q E + + + + Sbjct: 1155 KKINEIENLKNELKNKELTLEHMETERLELAQKLN----------ENYEEVKSITKERKV 1204 Query: 6249 HKSLLEQFTPKEKNKLTSHLESKALEIQLNLIPEMARKSLQMFNFYPKGTISKDNSWRFY 6308 K L + F + HL EI+ + ++ L++ + + K + R Sbjct: 1205 LKELQKSFETER-----DHLRGYIREIEATGL--QTKEELKIAHIHLKEHQETIDELRRS 1257 Query: 6309 SRHKTMNFMSLEGTDTIEPNSKHKHQKDSPLASNMKTLIVDVS--SDSEETITKLQSINK 6366 KT ++ + + S K Q++ P+ + L+ +V S+++ET+ +L+ + + Sbjct: 1258 VSEKTAQIINTQDLE----KSHTKLQEEIPVLHEEQELLPNVKEVSETQETMNELELLTE 1313 Query: 6367 LENGTSAVTSA----SEMLLPHTLQNHSVKEKGKLLMHFSVKT----LEIQMKAFPRIVR 6418 + T A + L Q + K ++KT LE++ +R Sbjct: 1314 QSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIR 1373 Query: 6419 ESYAMTSAHERKKPLS 6434 E+ A + K+ S Sbjct: 1374 ETLAKIQESQSKQEQS 1389 Score = 41.2 bits (95), Expect = 0.036 Identities = 134/658 (20%), Positives = 247/658 (37%), Gaps = 134/658 (20%) Query: 3909 PYSKVGTIEGEEAMRIKMRSSFSQPNLQESSDTEKTAYEKCISDNISNSVKKALESILQK 3968 PY V + +EA+ + R Q + +T + D ++ +++ + +LQK Sbjct: 333 PY--VNEVSTDEALLKRYRKEIMDLKKQLEEVSLETRAQAMEKDQLAQLLEE--KDLLQK 388 Query: 3969 EQRQKMEKIRALKKMKSSISQGIQLDIKEQEKR--------IEHIKGEPSVLLTNACASI 4020 Q +K+E + + SS++ +Q ++K + KR I +K N +I Sbjct: 389 VQNEKIENLTRMLVTSSSLT--LQQELKAKRKRRVTWCLGKINKMKNSNYADQFNIPTNI 446 Query: 4021 PSPSH-LQLDTRREKAEYVTEITRYYLPELSHQKSSEAGEKADGVASKGDITIKVQKAK- 4078 + +H L ++ RE E V + + L E A + ++ +I ++ + Sbjct: 447 TTKTHKLSINLLREIDESVCSESDVFSNTLDTLSEIE-WNPATKLLNQENIESELNSLRA 505 Query: 4079 -------DYMQ---QKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPLNTKEPGKMDQE 4128 DY Q +KE+ E+K+ K D+ E K KK L + + Sbjct: 506 DYDNLVLDYEQLRTEKEEMELKLKEKNDLDEFEALERKTKKDQEMQLIHEISNLKNLVKH 565 Query: 4129 AQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADGVGIEQGKMDGD 4188 A E +D E E K + + RE ++Q K E + QK + + KMD Sbjct: 566 A-EVYNQDLENELSSKVE--------LLREKEDQIKKLQEYIDSQKLENI-----KMD-- 609 Query: 4189 KNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSSETGKKANGVP 4248 L +E ED P+ K + + + Sbjct: 610 ----------------------LSYSLESIED-----------PKQMKQTLFDAETVALD 636 Query: 4249 SEGDSA---SEVQKAKDYMQQKEEDESKQETVLFLHLPSESSLTCYELNTRKEGEEDLQG 4305 ++ +SA SE + K+ M K+ + + ++ L +L +K+ + DL+ Sbjct: 637 AKRESAFLRSENLELKEKM--------KELATTYKQMENDIQLYQSQLEAKKKMQVDLEK 688 Query: 4306 IIKSATLQLRQQKSFDAGKIAHTKSFGVDSSNDVKTVQEYKPQKEVDRGKTVSVDYIMQP 4365 ++SA ++ + S GK+ ++ + +Q+ + KEV+ + + Sbjct: 689 ELQSAFNEITKLTSLIDGKVPKDLLCNLELEGKITDLQK-ELNKEVEENEALR------- 740 Query: 4366 EGTIFEAEQLSLPHTLNIPGSSGSKTREVLTNIKEKLRHVQERKSELDVFLTIPSLSHCK 4425 E I +E SLP S + R+ + + E+L + K +L + H Sbjct: 741 EEVILLSELKSLP-------SEVERLRKEIQDKSEELHIITSEKDKL-----FSEVVH-- 786 Query: 4426 LDKRTAGKKEEQGVTRSFLPPSWHMESSDTGKLKYTLSYLNDITGDSNRTKYMAQIQKDK 4485 + R G EE G T+ L + S D + +T +M QK K Sbjct: 787 KESRVQGLLEEIGKTKDDLATTQSNYKS------------TDQEFQNFKTLHMDFEQKYK 834 Query: 4486 ANISEKSVMHPEYIAVKAE-----------KSPLSHILKTKELQVNISQQGEKAQEGE 4532 + E M+ E + + E K+ LS+ KT+ELQ + E+ E E Sbjct: 835 MVLEENERMNQEIVNLSKEAQKFDSSLGALKTELSY--KTQELQEKTREVQERLNEME 890 Score = 37.4 bits (85), Expect = 0.52 Identities = 160/862 (18%), Positives = 327/862 (37%), Gaps = 115/862 (13%) Query: 2166 RTRRQNLDGHITEEKEEVQENVAAIFLGLLDFFMPVLSDSKNQRNTAQLSEKEIIFNAKC 2225 +T ++ L+ + KE ++E +A I + K+ T +SE E Sbjct: 1355 KTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEME------- 1407 Query: 2226 LTMKEKKSSISQIHKINRESTRKHRKKCKSYLKTVSNRK--CQENHGHITEEEEEVQENS 2283 K K S++ +I +I K ++ +K+V+ K Q + E ++++EN Sbjct: 1408 -QFKPKDSALLRI-EIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENI 1465 Query: 2284 PATFLGPLDFFMPVLSDSKNQINTIQLSERKIILNPKCLTMKEKKPPISQIHKISRQFTT 2343 L+ ++ + ++ L E++ +N + + EK+ IS I K Sbjct: 1466 KEIVAKHLE------TEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQLEAIND 1519 Query: 2344 KHRKKLES--------NLK---------TKLKAMWQGENVADT-FPNTTSFTPDSSDIKR 2385 K + K++ N+K +LK + D+ + S + ++ + Sbjct: 1520 KLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQ 1579 Query: 2386 QSGFQTEIDMRISGLSHTQPTQIESLAEGIARYSDPIDKRRTSNLVKGAKLHDRESGEEK 2445 +S Q EI + I + +++ + E + D + K T +V AK+ + + E + Sbjct: 1580 ES--QEEIQIMIK-----EKEEMKRVQEALQIERDQL-KENTKEIV--AKMKESQEKEYQ 1629 Query: 2446 QEHLTEMDPFYAENFMANTYLRKDRHLGKSEDVLLGETFFSKSQIYKGNSEKNVKIEKNK 2505 +T ++ E +L++ K + +QI N E+ + K + Sbjct: 1630 FLKMTAVNETQ-EKMCEIEHLKEQFETQKLNLENIETENIRLTQILHENLEEMRSVTKER 1688 Query: 2506 NGKESLKVGLARMEKSDNCAELSEATDDAISNKYDKQN---IGHSVLKEN--AFCNLAAI 2560 + S++ L ++E+ +L E + I+ +KQ I H LKE+ L I Sbjct: 1689 DDLRSVEETL-KVERD----QLKENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGI 1743 Query: 2561 VPDSVGRHSPASEEMKRQNGRLKMADRSSPQGRPLQAKQSAVSQSPDTAGYAVVSNNKEQ 2620 V + S ++++ N LK D + + Q +VS ++ Sbjct: 1744 VSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDK 1803 Query: 2621 KQNFKAQKTEAEVDLIDQEAKINVAEEFNPESVFFSKIHPLQIENKKEFKTADWKTRADP 2680 N + DL + AK+ E + K + Q+ K+ K ++ Sbjct: 1804 LSNMQK-------DLENSNAKLQ-------EKIQELKANEHQLITLKKDVNETQKKVSEM 1849 Query: 2681 KTFALPKKQQELCVSGTIWSYPNPYTSISPKIIRHKDKAKTADVESTMHTKQIKLKAKRI 2740 + K Q L +S N + + K K D + + LK +R Sbjct: 1850 EQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERD---NLRRVEETLKLERD 1906 Query: 2741 PVSQLLEYGTASNKKELRGNIQQQKSFQLS-KNAVHRVLKAVYDSGYCVSSIKKLTEVKM 2799 + + L+ T + E++ ++ + K V ++ + + + +S I+K Sbjct: 1907 QLKESLQE-TKARDLEIQQELKTARMLSKEHKETVDKLREKISEKTIQISDIQK------ 1959 Query: 2800 EKDKPKDRTCILPQPKLEKPLKEMQRSLSGCTDMSSILRKQEQDIREKEQ-KHQSISEDI 2858 + DK KD +L+K ++E+Q+ + + + I E EQ K Q ++++ Sbjct: 1960 DLDKSKD--------ELQKKIQELQKKELQLLRVKEDVNMSHKKINEMEQLKKQFEAQNL 2011 Query: 2859 SQYYIGPLRISSQQINYSSFDAPRIRTDE--ELEFLIAQRAKEKDVGIAKHSVSIPWERE 2916 S + + + S + RI E EL + E+D IA I +R+ Sbjct: 2012 SMQSVRMDNFQLTKKLHESLEEIRIVAKERDELRRIKESLKMERDQFIATLREMIARDRQ 2071 Query: 2917 -------------GSKRLDIPLNSKGQNIF-----FTELDTSQQKICQ-----EQELLKQ 2953 G + L L K I ++E+D + + + E+E+ Q Sbjct: 2072 NHQVKPEKRLLSDGQQHLTESLREKCSRIKELLKRYSEMDDHYECLNRLSLDLEKEIEFQ 2131 Query: 2954 EDISMTNLGSMACPIMEPLHLE 2975 +++SM +++ P ++ H+E Sbjct: 2132 KELSMRVKANLSLPYLQTKHIE 2153 Score = 36.2 bits (82), Expect = 1.2 Identities = 240/1309 (18%), Positives = 506/1309 (38%), Gaps = 179/1309 (13%) Query: 4902 EQKRKIQEDKNKQVKGLPSINTSLLTPPYLKFDTTEGQENVIRIAKVSLPQSRSKESSDA 4961 EQK K+ ++N+++ +N L+ KFD++ G K Q +++E + Sbjct: 830 EQKYKMVLEENERMNQ-EIVN---LSKEAQKFDSSLGALKTELSYKTQELQEKTREVQE- 884 Query: 4962 GRIACPEATHGELSS------DVKQLKAHLLQKEEKDREKVADMTSVLDPNKMYLKAK-- 5013 R+ E +L + V++ K + +K ++ E+V +T D K ++ Sbjct: 885 -RLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQI 943 Query: 5014 -----KSPVLHTHSFS-DLQWKTR------EQEEEKVQKVKSGPGVMLSKSPSRSSPLHL 5061 KS + T + + D Q + R +Q +E + +KS +S+ SR+ LH+ Sbjct: 944 ERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKS----KISEEVSRN--LHM 997 Query: 5062 NVNTG-----FQEESIPILTRPSFPLVKLQ-VSPDTEGGTCIRPIAGDILIYLQKGKHVS 5115 NTG FQ++ + I + Q ++ D + I Q+ K S Sbjct: 998 EENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIE----------QQRKIFS 1047 Query: 5116 QNKEEDDVQIVSILIFPKHQEEKVQECEGEPGVVLTKSTSLPSLSQLELDKETHLGNEML 5175 +E++++Q + + + ++ K L ++ + +Q EL LG+E+ Sbjct: 1048 LIQEKNELQQMLESVIAEKEQLKTD---------LKENIEMTIENQEELRL---LGDELK 1095 Query: 5176 RLKRPILRRISHI----GETVHRESVVGDIPKDVKNEKQHIPQKEER----------NQK 5221 + + + + +H GE + ++ + +K + Q + +K+++ QK Sbjct: 1096 KQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQK 1155 Query: 5222 KIIDMRGTDITLKSKKSPRSCM-LHRTELHVNIGGQGRKEHEGQDKPPGMI-QRKMCILF 5279 KI ++ LK+K+ M R EL +K +E ++ + +RK+ Sbjct: 1156 KINEIENLKNELKNKELTLEHMETERLEL-------AQKLNENYEEVKSITKERKVLKEL 1208 Query: 5280 SKPLPSNLKLERATHADEERLGGKTSFVLPLMPSALPDTEKTADAEARSGDVRKGKPHRS 5339 K + R + E G +T L + L + ++T D RS + + + Sbjct: 1209 QKSFETERDHLRGYIREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINT 1268 Query: 5340 QKENRHEVKTIDMRFRIHCQEARISPMSHILNAKELVLNINKLEKKVHKDKDEACVVLSR 5399 Q + K + +H ++ + + + +E +N+LE + + L+R Sbjct: 1269 QDLEKSHTKLQEEIPVLHEEQELLPNVKEVSETQE---TMNELELLTEQSTTKDSTTLAR 1325 Query: 5400 TFLSIPSAPPLYLDSGNKTDKDTPGITGSSCPQRTLHVPSNTQKITNRDSVEGVDKNVVK 5459 + + +S + T + L V + K R+++ + ++ K Sbjct: 1326 IEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSK 1385 Query: 5460 QAEQYVPRPEAEQQLTSNFMISVQQRNQPSRVTSEEDLNQLVLNSRDEDIYFTGFGTIRS 5519 Q EQ + E + + T+ + ++Q ++ L L+ R ++ + + Sbjct: 1386 Q-EQSLNMKEKDNE-TTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKE 1443 Query: 5520 G---KRPEWLFTGKKAQPVKYKTETLTAFLSYPTMDATKMGG--LEEDTEIMDNLNHKIS 5574 +R + + + Q + E + L T + K+ L+E E ++ L +S Sbjct: 1444 KDDLQRLQEVLQSESDQLKENIKEIVAKHLE--TEEELKVAHCCLKEQEETINELRVNLS 1501 Query: 5575 PKASVSLIRKISKELYVTLGTPASSKGFSVSERYAHQQETSSKVSPELAGSCKFDKP-KE 5633 K + I I K+L + +K + E Y +++ + K E+ K KE Sbjct: 1502 EKETE--ISTIQKQLEA-INDKLQNK---IQEIYEKEEQFNIKQISEVQEKVNELKQFKE 1555 Query: 5634 DGQSNDRISKMFSPKVLAPQTKGSLKKISIVTNWNAPQNIEEQDIVMKKQVIRRCEHGHK 5693 ++ D + K+L +TN E Q ++ +K+ ++R + + Sbjct: 1556 HRKAKDSALQSIESKMLE------------LTNRLQESQEEIQIMIKEKEEMKRVQEALQ 1603 Query: 5694 TRTNTILSKFPLQSGKQKTPSETDVDKKTTAHLSLQMLPGIHMDMTEIDPAKGGRKQALL 5753 + + K K E K L + + M EI+ K + L Sbjct: 1604 IERDQLKENTKEIVAKMKESQE-----KEYQFLKMTAVNETQEKMCEIEHLKEQFETQKL 1658 Query: 5754 ISEQEEG----VLELLPKSLFPPWTFQFQSGDLEEKHQTDANTNINLEQKKLEMDNDSTV 5809 E E + ++L ++L + + DL +T + +E+ +L+ + T+ Sbjct: 1659 NLENIETENIRLTQILHENLEEMRSVTKERDDLRSVEET-----LKVERDQLKENLRETI 1713 Query: 5810 N---QKEGKLKIGTNRALHLQEEKTEMHKARTANLEKERGRMDTSSSAHPHLPSLKAEES 5866 +K+ +LKI +HL+E + + K R EK + +LKA++ Sbjct: 1714 TRDLEKQEELKIVH---MHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDL 1770 Query: 5867 QMKTQV-ITH---RENSRLI-------------MQKQKKELEASNAKQSIQLQKLFQRNV 5909 +++ ++ I H +E I + +K+LE SNAK ++Q+L Sbjct: 1771 KIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANE- 1829 Query: 5910 LDSFYSYVPLSPKCKD-QKGRLTIRDLKRELSTKYLT---MKIQNHPIPQMLNITGRGTP 5965 + + L + QK + LK+++ + LT ++I+N + Q L+ Sbjct: 1830 ----HQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMK 1885 Query: 5966 SNRKKLEYDVKLKNIASWSKDVSGIFIRSLSISIMRSPHTDPKTNLE-REKRICLPKFQE 6024 S K+ + +++ +D L S+ + D + E + R+ + +E Sbjct: 1886 SVMKERDNLRRVEETLKLERD-------QLKESLQETKARDLEIQQELKTARMLSKEHKE 1938 Query: 6025 KSPNTSEMSKRDTLTIVKGEQNFTNTVPQDPQPFAVDKQQMQKLPNVKSEANL------R 6078 E T+ I +++ + + + +++ +L VK + N+ Sbjct: 1939 TVDKLREKISEKTIQISDIQKDLDKSKDELQKKIQELQKKELQLLRVKEDVNMSHKKINE 1998 Query: 6079 SEMNKKYLKAQTKERIVPEHDVSRIIKK-----PDLRIIEQEEKILKRI 6122 E KK +AQ D ++ KK ++RI+ +E L+RI Sbjct: 1999 MEQLKKQFEAQNLSMQSVRMDNFQLTKKLHESLEEIRIVAKERDELRRI 2047 Score = 36.2 bits (82), Expect = 1.2 Identities = 149/830 (17%), Positives = 313/830 (37%), Gaps = 117/830 (14%) Query: 247 QAQYINHNQESIKSQPESKASNFAQPEDVMKKPFSSSTQDSFQSQDLDR----NQHFVEV 302 Q Q +N +E S+ + K + ++ +K T + +++ L+ N+++ EV Sbjct: 1140 QQQLLNVQEEM--SEMQKKINEIENLKNELKN--KELTLEHMETERLELAQKLNENYEEV 1195 Query: 303 PSIVEAKYSVKGLESDEHLGEDQHCVWFIDSNKVKYSIKGQDTIFKNAEFLVLTLNPNLV 362 SI + + +K L+ D H +I + G T E + ++ Sbjct: 1196 KSITKERKVLKELQKSFETERD-HLRGYIR----EIEATGLQT---KEELKIAHIHLKEH 1247 Query: 363 TEDMPQLRSVKAQGQQQIVSS---ELNQDSVYSSVPLL----STIKGQKNRRKTPDSKSK 415 E + +LR ++ QI+++ E + + +P+L + K +T ++ ++ Sbjct: 1248 QETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKEVSETQETMNE 1307 Query: 416 LSLNVPSLKAKKTPTSQVFQITVCHTLKNRNELGCKNNTEKKELHERKDISDIALHLISV 475 L L K + T ++ NE ++ E K L + +D + V Sbjct: 1308 LELLTEQSTTKDSTTLARIEMERLRL----NEKFQESQEEIKSLTKERDNLKTIKEALEV 1363 Query: 476 SKLILPYVKNYSRKQLVKVMPGLIKCGHFLQKQNKSPDTEKINYAGPLEETGISDITKKE 535 +K + R+ L K+ K L + K +T KI + S + + E Sbjct: 1364 KH---DQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIE 1420 Query: 536 KEYDKENKRLKNISPKM---------LPQLEQSFMVNTVQLKAPCL-LVETNGKSKESLK 585 E +KRL+ +M L +L++ + QLK +V + +++E LK Sbjct: 1421 IEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELK 1480 Query: 586 DS--ITQAKGIGITEFHVLNSKKPFDLHIPKHKTSLEEAISKPMQKLVSSPEMESNNRMK 643 + + + I E V S+K + I + LE K K+ E E +K Sbjct: 1481 VAHCCLKEQEETINELRVNLSEK--ETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIK 1538 Query: 644 IQEDLQSSENSHLQLSNGEELPTSTPKTQRCFPRENTQKQKDFLELVLELSNVGLLISLG 703 ++Q N Q + S ++ E T + ++ E + Sbjct: 1539 QISEVQEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEI------------- 1585 Query: 704 SKMHKSSEELEAIKIQVNTESVNLKESKPLILNVTEDSDLRESEELECNTGS-------N 756 M K EE++ ++ + E LKE+ I+ ++S +E + L+ + Sbjct: 1586 QIMIKEKEEMKRVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCE 1645 Query: 757 ITNMHQDKETSD------AFHSATYTTISQLPDTETHSISKAKAD------TLRIIR--- 801 I ++ + ET + T I E S++K + D TL++ R Sbjct: 1646 IEHLKEQFETQKLNLENIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQL 1705 Query: 802 -------LSHSASKQE--KLPDEKETQNAEYIDK--SCTFKKPQQCDRKEQEKEANSELT 850 ++ KQE K+ ++ E IDK +K + +++ E +++ Sbjct: 1706 KENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDAL 1765 Query: 851 QGFRFSI---------HLKQKPKYVKFQMEQISSGSSKAPNKEQEVQPQTLSTQTILENS 901 + I HLK++ + + +S + K N +++++ Q ++ Sbjct: 1766 KAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQEL 1825 Query: 902 PCPMMDPFQVEKVKQSTDRPTDRESAGDPKNPLTMPENLPVGELLIETTEYSVPFGGNLQ 961 + Q+ +K+ + + S + ++L + +L IE + NL+ Sbjct: 1826 KA---NEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLE 1882 Query: 962 KTTDSHIAEEKEDVKRYLPAVALGSFNNHLLTLPYFKRQEIKKKLSETKS 1011 + + +E+++++R + L +R ++K+ L ETK+ Sbjct: 1883 EM--KSVMKERDNLRRVEETLKL-------------ERDQLKESLQETKA 1917 >gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] Length = 1411 Score = 63.5 bits (153), Expect = 7e-09 Identities = 175/869 (20%), Positives = 337/869 (38%), Gaps = 149/869 (17%) Query: 2142 KSTTSKSMIDKLLYNTAARCILSNRTRRQNLDGHITEEKEEVQENVAAIFLGLLDFFMPV 2201 +STT+K + R I + QNL+ + + KE N++ + D + + Sbjct: 498 QSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKE----NISLLEKEREDLYAKI 553 Query: 2202 LSDSKNQRNTAQLSEKEIIFNAKCLTMKEKKSSISQIHKINRESTRKHRKKCKSYLKTVS 2261 + QL EK + + EK + S+ HK +E+ ++ K++L+ Sbjct: 554 QAGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQ 613 Query: 2262 NR------KCQENHGHITEEEEEVQE--------------------NSPATFLGPLDFFM 2295 +R E + + E +E+V + A LD Sbjct: 614 DRVLSLETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQ 673 Query: 2296 PVLSDSKNQINTIQLSERKIILNPKCLTMKEKKPPISQIHKISRQFTTKH------RKKL 2349 L D + ++N I L+ +++K+ SQ+ +++ K+ ++L Sbjct: 674 NALQDKQQELNKITTQ-----LDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEEL 728 Query: 2350 ESNLKTKLKAMWQGENVADTFPNTTSFTPDSSDIKRQSGFQTEIDMRISGLSHTQPTQIE 2409 E +K KL+A D+ S D+++Q T++++R + LS Q+E Sbjct: 729 EGQIK-KLEA--------DSLEVKASKEQALQDLQQQRQLNTDLELRATELSK----QLE 775 Query: 2410 SLAEGIARYSDPIDKRRTSNLVKGAKLHDRESGEEKQ------EHLTEMDPFYAE--NFM 2461 E ++ S +D ++ S ++ K + EEKQ E L++ E N Sbjct: 776 MEKEIVS--STRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNR 833 Query: 2462 ANTYLRKDRHLGKSEDVLLGETFFSKSQIYK-GNSEKNVKIEKNKNGKESLKVGLARMEK 2520 T + + + + ++ L+ E K ++ K +S KN K E K ++ K + +EK Sbjct: 834 IQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKG-KAAILDLEK 892 Query: 2521 SDNCAELSEATDDAISNKYDKQN-IGHSVLKENAFCNLAAIVPDSVGRHSPASEEMKRQN 2579 + C EL + N +Q + S+ KE + + +S+ ++ +QN Sbjct: 893 T--CKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQN 950 Query: 2580 GRLKMADRSSPQGRPLQAKQSAVSQSPDTAGYA-----VVSNNKEQKQNFKAQKTEAEVD 2634 + + QG + KQS+ + V E + + Q T+A + Sbjct: 951 EK----EEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQE 1006 Query: 2635 LIDQEAKINVAEE-FNPESVFFSKIHPLQIENKKEFKTADWKTRADPKTFA--LPKKQQE 2691 L ++ KI+V + + F ++ + E TR D K+ L Q++ Sbjct: 1007 LAAEKEKISVLQNNYEKSQETFKQLQSDFYGRESELLA----TRQDLKSVEEKLSLAQED 1062 Query: 2692 LCVSGTIWSYPNPYTSISPKIIRHKDKAK-TADVESTMHTKQIKLKAKR---IPVSQLLE 2747 L + N K+I+ AK T + +S +Q++ + K I + L+ Sbjct: 1063 LISNRNQIGNQN-------KLIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSLK 1115 Query: 2748 YGTASNKKELRGNIQQQKSFQLSK-NAVHRVLKAVYDSGYCVSSIKKLTEVKMEKDKPKD 2806 N+K I++ K Q + ++ LK+ + + SIK++T +K K Sbjct: 1116 EKELVNEKSKLAEIEEIKCRQEKEITKLNEELKS-----HKLESIKEITNLKDAKQ---- 1166 Query: 2807 RTCILPQPKLEKPLKEMQRSLSGCTDMSSILRKQEQDIREKEQKHQSISEDISQYYIGPL 2866 +L Q KLE L+ SL + ++ +Q ++++ +K + E++ + +I Sbjct: 1167 ---LLIQQKLE--LQGKADSLKAAVEQE---KRNQQILKDQVKKEE---EELKKEFI--- 1212 Query: 2867 RISSQQINYSSFDAPRIRTDEELEFLIAQRAKEKDVGIAKHSVSIPWEREGSKRLDIPLN 2926 E E + KEK+VG+ KH E E + I Sbjct: 1213 ---------------------EKEAKLHSEIKEKEVGMKKHE-----ENEAKLTMQITAL 1246 Query: 2927 SKGQNIFFTELDTSQQKICQEQELLKQED 2955 ++ E +SQ+++ EL KQ D Sbjct: 1247 NENLGTVKKEWQSSQRRV---SELEKQTD 1272 Score = 48.1 bits (113), Expect = 3e-04 Identities = 120/613 (19%), Positives = 241/613 (39%), Gaps = 58/613 (9%) Query: 3819 ELSDTMEKCEQPIDDSLSSIEKAKHMPQKDKD------RVEKALEKIMHSKRIALE--VK 3870 +L D E C Q EK + QK ++ ++E ++ SK AL+ + Sbjct: 696 KLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQ 755 Query: 3871 QPSIFQELELNIKEKGGKIQEDKEVEIWSKPFASISFLPYSKVGTIEGEEAMRIKMRSSF 3930 Q + +LEL E +++ +KE+ S + L K E E+++ K+ Sbjct: 756 QRQLNTDLELRATELSKQLEMEKEI-------VSSTRLDLQKKS--EALESIKQKLTKQE 806 Query: 3931 SQPNLQESSDTEKTAYEKCISDNISNSVKKALESI--LQKEQRQKMEKIRALKKMKSSIS 3988 + + + + K + ++N ++ + + ++ E+ M ++ +K S +S Sbjct: 807 EEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVS 866 Query: 3989 QGIQLDIKEQEKRIEHIKGEPSVL-LTNACASIPSPSHLQLD-TRREKAEYVTEITRYYL 4046 ++ E EK E+ KG+ ++L L C + +Q++ T +E+ E + + Sbjct: 867 DSLKNSKSEFEK--ENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKE-- 922 Query: 4047 PELSHQKSSEAGEKADGVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLK 4106 E SHQ E + + + T+K + ++ Q +E+K S+++ E + Sbjct: 923 KEASHQLKLELNSMQEQLIQAQN-TLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQGE 981 Query: 4107 AKKALSQDLPLNTKEPGKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMD 4166 K A+ Q L K ++ Q AQE E +EK+ K Sbjct: 982 LKIAVLQKTELENKLQQQLTQAAQELAAE----------------KEKISVLQNNYEK-S 1024 Query: 4167 HEVEEQQKADGVGIEQGKMDGDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIR 4226 E +Q ++D G E + ++ + L L +++ + Q + Sbjct: 1025 QETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISN-------RNQIGNQNKLI 1077 Query: 4227 PGILQPRHQKSSETGKKANGVPSEGDSASEVQKAKDYMQQKE--EDESKQETVLFLHLPS 4284 + + ++ KK + + ++QK K +++KE ++SK + + Sbjct: 1078 QELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKS-LKEKELVNEKSKLAEIEEIKCRQ 1136 Query: 4285 ESSLTCYELNTRKEGEEDLQGI--IKSATLQLRQQKSFDAGKIAHTKSFGVDSSNDVKTV 4342 E +T + E ++ I +K A L QQK GK K+ V+ + + Sbjct: 1137 EKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKA-AVEQEKRNQQI 1195 Query: 4343 QEYKPQKEVDRGKTVSVDYIMQPEGTIFEAEQLSLPHTLNIPGSSGSKT--REVLTNIKE 4400 + + +KE + K ++ + I E E H N + T E L +K+ Sbjct: 1196 LKDQVKKEEEELKKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITALNENLGTVKK 1255 Query: 4401 KLRHVQERKSELD 4413 + + Q R SEL+ Sbjct: 1256 EWQSSQRRVSELE 1268 Score = 48.1 bits (113), Expect = 3e-04 Identities = 88/384 (22%), Positives = 163/384 (42%), Gaps = 61/384 (15%) Query: 377 QQQIVSSELNQDSVYSSVPLLSTIKGQKNRRKTPDS--KSKLSLNVPSLKAKKTPTSQVF 434 + +I ELN + + ++V L +K +K T S K KLS SLK K+ + Sbjct: 822 ETKIQHEELN-NRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKEN 880 Query: 435 QI---------TVCHTLKNRNELGCKNNT-EKKELHERKDISDIALHLISVSKLILPYVK 484 Q C LK++ ++ +N E+KEL + + A H + + Sbjct: 881 QKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLEL------- 933 Query: 485 NYSRKQLVKVMPGLIKCGHFLQKQNKSPDTEKINYAGPLEETGISDITKKEKEYDKENKR 544 N ++QL++ L KQN+ + + L+++ +K+K+ + Sbjct: 934 NSMQEQLIQAQNTL--------KQNEKEEQQLQGNINELKQSS----EQKKKQIEALQGE 981 Query: 545 LK-------NISPKMLPQLEQSFMVNTVQLKAPCLLVETNGKSKESLKDSITQAKGIGIT 597 LK + K+ QL Q+ + + +L KS+E+ K + G Sbjct: 982 LKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQSDFYG---R 1038 Query: 598 EFHVLNSKKPFDLHIPKHKTSLEEAISKPMQKLVSSPEMESNNRMKIQEDLQSSENSHLQ 657 E +L +++ S+EE +S + L+S+ N IQE L++++ + Q Sbjct: 1039 ESELLATRQDLK--------SVEEKLSLAQEDLISNRNQIGNQNKLIQE-LKTAKATLEQ 1089 Query: 658 LSNGEELPTSTPKTQRCFPRENTQKQKDFLE--LVLELSNVGLLISLGSKMHKS----SE 711 S +E +RC ++ QK+K E LV E S + + + + K +E Sbjct: 1090 DSAKKEQQLQ----ERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNE 1145 Query: 712 ELEAIKIQVNTESVNLKESKPLIL 735 EL++ K++ E NLK++K L++ Sbjct: 1146 ELKSHKLESIKEITNLKDAKQLLI 1169 Score = 43.5 bits (101), Expect = 0.007 Identities = 121/607 (19%), Positives = 230/607 (37%), Gaps = 122/607 (20%) Query: 3687 KLQASSNARRVSSAESIN----RDSLSNVIESKCFPQKKKEDRENIVDVKDIMGLKCITL 3742 KL+A S + S +++ + L+ +E + K+ + E K+I+ + L Sbjct: 734 KLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEME-----KEIVSSTRLDL 788 Query: 3743 KGKKSLFRHLLHGKEPQRSNKKLEKMTQEDESNLNVVQNKLCASILSPPHLEWNPRIKEV 3802 + K + Q K++ K E S +Q H E N RI+ Sbjct: 789 QKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQ-----------HEELNNRIQTT 837 Query: 3803 YMRGITRFCLSSSTQQELSDTMEKCEQPIDDSLSSIEKAKHMPQKDKDRV---EKALEKI 3859 + ELS +K + D +S + + QK K + EK +++ Sbjct: 838 VTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKEL 897 Query: 3860 MHSKRIALEVKQPSIFQELELNIKEKGGKIQEDKEVEIWSKPFASISFLPYSKVGTIEGE 3919 H ++ +E ++E KE++ K E E Sbjct: 898 KHQLQVQME------------------NTLKEQKELK---------------KSLEKEKE 924 Query: 3920 EAMRIKMRSSFSQPNLQESSDTEKT--AYEKCISDNISNSVKKALESILQKEQRQKMEKI 3977 + ++K+ + Q L ++ +T K E+ + NI+ + + + Q E Q KI Sbjct: 925 ASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQGELKI 984 Query: 3978 RALKKMKSSISQGIQLDIKEQEKRIEHIKGEPSVLLTNACASIPSPSHLQLDTRREKAEY 4037 L+K + + +Q + + + + K + SVL N S + LQ D ++E Sbjct: 985 AVLQK--TELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQSDFYGRESEL 1042 Query: 4038 VTEITRYYLPELSHQKSSEAGEKADGVASKGDI-----------TIKVQKAKDYMQQKED 4086 + TR L + +K S A E D ++++ I T K +D ++++ Sbjct: 1043 LA--TRQDLKSVE-EKLSLAQE--DLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQ 1097 Query: 4087 DEVKISAKKDIMHPEDKGLKAKKALSQDLPLNTKEPGKMDQEAQEQGKEDREGEEQGKED 4146 + + A +DI ++K LK K+ +++ L E K QE KE + E+ K Sbjct: 1098 LQERCKALQDIQ--KEKSLKEKELVNEKSKLAEIEEIKCRQE-----KEITKLNEELKSH 1150 Query: 4147 RRGAGQEKVDREDKEQGKMDHEVEEQQKADGVGIEQGKMDGDKNEQERVLFLYLPSNSSL 4206 + + +E + +D +Q + ++E Q KAD Sbjct: 1151 KLESIKEITNLKDAKQLLIQQKLELQGKADS----------------------------- 1181 Query: 4207 THYILDTRIEGEEDQQGIIRPGILQPRHQKSSETGKKANGVPSEGDSASEVQKAKDYMQQ 4266 L +E E+ Q I++ + K E K + E SE+++ + M++ Sbjct: 1182 ----LKAAVEQEKRNQQILKDQV------KKEEEELKKEFIEKEAKLHSEIKEKEVGMKK 1231 Query: 4267 KEEDESK 4273 EE+E+K Sbjct: 1232 HEENEAK 1238 Score = 38.5 bits (88), Expect = 0.23 Identities = 183/906 (20%), Positives = 344/906 (37%), Gaps = 147/906 (16%) Query: 1092 SHIKLVQEESQIEREEKYPYFINEGNESQNTLDAKLQDEVKGVKETLPKAVLHDSCNLGL 1151 S +L E Q+E + + I + + A+L E+ +K +D Sbjct: 133 SSAELQSLEQQLEEAQTENFNIKQMKDLFEQKAAQLATEIADIKSK------YDEERSLR 186 Query: 1152 DAHLEKEIKTEKEMHQPIPFTETIIESVVSPIMELSHAENVKSTQKTQTDCKCTADSETP 1211 +A +K + +E+++ T+I+ + + +++ E+V +K + D+ T Sbjct: 187 EAAEQKVTRLTEELNKEA----TVIQDLKTELLQRPGIEDVAVLKKELVQVQTLMDNMTL 242 Query: 1212 SPISGKSLIGDPLNQTRESYIPSNGSDTREMGYCFAEEKTEIPKDLPATSPETFNYCTPV 1271 + D + + Y S + ++ E + P+++ E + V Sbjct: 243 ERERESEKLKDECKKLQSQYASSEATISQ-----LRSELAKGPQEVAVYVQELQKLKSSV 297 Query: 1272 LSCSKVMKKRVTFALTTSTAKPKCVNTKAVKPSISETVS-----VTSHRKKSELDFKTKF 1326 +++ +K T LT + K + TK + E+VS T H+K +LD + Sbjct: 298 ---NELTQKNQT--LTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQK--DLDCQQLQ 350 Query: 1327 KKINQTKGLVPECLNTLCSPMHSRLQREFCLPASQLKQGETADKTYTDVFAK-NSISHDR 1385 +++ ++ T +H L + ++ + Y + A+ + R Sbjct: 351 SRLSASE--------TSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQR 402 Query: 1386 EEKLQDGKEEE------HKVLLEAAPQLSQHLGSEAGQMKEIH-LESDPVLNC--LTLEL 1436 EEK Q G + + H LLE QL G G++KE L S+ +++ +L Sbjct: 403 EEKEQHGLQLQSEINQLHSKLLETERQL----GEAHGRLKEQRQLSSEKLMDKEQQVADL 458 Query: 1437 HINGQRLQHQTGFEQTTLETSLQMGPLEAEELQKANETENDIKVLGGPKIPPPKALQALE 1496 + RL+ Q E+ T T LQ +L K + + QAL+ Sbjct: 459 QLKLSRLEEQLK-EKVTNSTELQ------HQLDKTKQQHQE--------------QQALQ 497 Query: 1497 NSDGLILNAYQKDNELVKSDEELNQPGSTNIQVQPQTHFTQTILKSTSCPTLDQFP-FEK 1555 S L Q D E V L Q G + ++Q Q ++ S ++ + K Sbjct: 498 QSTTAKLREAQNDLEQV-----LRQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYAK 552 Query: 1556 VESH----VRFSPLKSGEAKVDEIIFYAREGGISSDSSHQKEQAG---GTEKKETAIFGS 1608 +++ + L+ + E + E + SH++ Q ++++ + + Sbjct: 553 IQAGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAA 612 Query: 1609 CMPALSTPKTTRNLK-QFSDMKTLVNPKCGIIKAKKPSISYMLNIRAGAGPKRRKELSCN 1667 LS + L Q ++ K V+ IKAK + +L A +R +L + Sbjct: 613 QDRVLSLETSVNELNSQLNESKEKVSQLDIQIKAK----TELLLSAEAAKTAQRADLQNH 668 Query: 1668 LTT-------KMKELHQGKKGVDETYAFLTMTPDINKYSKVETEKDTLREKRLSSTQVKQ 1720 L T K +EL++ +D+ A L + S++E+ +EK LS Q + Sbjct: 669 LDTAQNALQDKQQELNKITTQLDQVTAKLQDKQE--HCSQLESHLKEYKEKYLSLEQKTE 726 Query: 1721 DTSPH-----EDSITSRDIKETLLQDEEQEERKQEPL-LKVIPQHLQHFMFRS-GQGKDL 1773 + DS+ + KE LQD +Q+ + L L+ Q M + L Sbjct: 727 ELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRL 786 Query: 1774 DFHKLENQGSRKILFVTKQDVPQQL--QPAEPIQREETKKCLQTQNGTICTVNSKLLPLK 1831 D K +TKQ+ +Q+ Q E + +ETK + N I T ++L +K Sbjct: 787 DLQKKSEALESIKQKLTKQEEEKQILKQDFETLS-QETKIQHEELNNRIQTTVTELQKVK 845 Query: 1832 SEDSVNGEVLTGAIKRGVPTDRKCMGEQHNSGKGEKAEFNKDLQ---ATVLELQKS---- 1884 E A+ + T + + + +S K K+EF K+ Q A +L+L+K+ Sbjct: 846 MEKE--------ALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKEL 897 Query: 1885 PHGGEAQKAN-------------------------LTDMESGSSNAMNMNVQHEREDKNI 1919 H + Q N L M+ A N Q+E+E++ + Sbjct: 898 KHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQL 957 Query: 1920 QKMLTE 1925 Q + E Sbjct: 958 QGNINE 963 Score = 37.7 bits (86), Expect = 0.40 Identities = 148/815 (18%), Positives = 306/815 (37%), Gaps = 130/815 (15%) Query: 14 PEKGSSDVQELQRIGQLLIHLQEKEKRITSSLTSEEK-----ECNFEDRILFSREILWSG 68 P++ + VQELQ++ + L +K + +T +L +E+ E + + + I Sbjct: 280 PQEVAVYVQELQKLKSSVNELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNI--QA 337 Query: 69 TSESEDQVSPSSESHVPSSNGISSSLPLFYSEVEETCLSHTEH---PDREYETIQFSSKK 125 T +D +S + +S + + SE E E + +Y+ ++ K+ Sbjct: 338 TLHQKDLDCQQLQSRLSASETSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQ 397 Query: 126 LFSMMKTNKNKNSGFSSDLSFSASRFTVENEDLDVAPCPLAHLFLSRDQVRLLEENVRNQ 185 L + + S+++ S+ L A L ++Q +L E + ++ Sbjct: 398 LQQQREEKEQHGLQLQSEINQLHSKLLETERQLGEAHGRL------KEQRQLSSEKLMDK 451 Query: 186 IPSKPKTKLGSRTTYQCSRSQESLNQNQPSVGMVISVQAQDSFPGQNAFQNQGLYEVQFT 245 +L + SR +E L + V +Q Q Q + Q L + T Sbjct: 452 EQQVADLQL------KLSRLEEQLKEK---VTNSTELQHQLDKTKQQHQEQQALQQ-STT 501 Query: 246 SQAQYINHNQESIKSQPESKASNFAQPEDVMKKPFSSSTQDSFQSQDLDRNQHFVEVPSI 305 ++ + ++ E + Q K E +++K ++++ + +R + ++ + Sbjct: 502 AKLREAQNDLEQVLRQIGDKDQKIQNLEALLQK-----SKENISLLEKEREDLYAKIQAG 556 Query: 306 VEAKYSVKGLESDEHLGEDQHCVWFIDSNKVKYSIKGQDTIFKNAEFLVLTLNPNLVTED 365 + L+ H ++Q ++ +K Q K A+ Sbjct: 557 EGETAVLNQLQEKNHTLQEQ-------VTQLTEKLKNQSESHKQAQ-------------- 595 Query: 366 MPQLRSVKAQGQQQIVSSELNQDSVYSSVPLLSTIKGQKNRRKTPDS--------KSKLS 417 ++ Q Q+Q QD V S ++ + Q N K S K++L Sbjct: 596 ----ENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQIKAKTELL 651 Query: 418 LNVPSLKAKKTPTSQVFQITVCHTLKNRNELGCKNNTEKKELHERKDISDIALHLISVSK 477 L+ + K + Q T + L+++ + K T+ ++ + + D H + Sbjct: 652 LSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKITTQLDQVTAK--LQDKQEHCSQLES 709 Query: 478 LILPYVKNY-SRKQLVKVMPGLIK---CGHFLQKQNKSPDTE------KINYAGPLEETG 527 + Y + Y S +Q + + G IK K +K + ++N L T Sbjct: 710 HLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATE 769 Query: 528 ISDITKKEKEY--------DKENKRLKNISPKMLPQLEQSFMVN----TVQLKAPCLLVE 575 +S + EKE K+++ L++I K+ Q E+ ++ T+ + E Sbjct: 770 LSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEE 829 Query: 576 TNGK-------------SKESLKDSITQAKG-IGITEFHVLNSKKPFDLHIPKHKTSLEE 621 N + KE+L ++ K + + NSK F+ K K ++ + Sbjct: 830 LNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILD 889 Query: 622 AISKPMQKLVSSPEMESNNRMKIQEDLQSS-----ENSH---LQLSNGEELPTSTPKTQR 673 + K ++L +++ N +K Q++L+ S E SH L+L++ +E T + Sbjct: 890 -LEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLK 948 Query: 674 CFPRENTQKQKDFLEL-------------------VLELSNVGLLISLGSKMHKSSEELE 714 +E Q Q + EL + L L L ++ ++++EL Sbjct: 949 QNEKEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELA 1008 Query: 715 AIKIQVNTESVNLKESKPLILNVTEDSDLRESEEL 749 A K +++ N ++S+ + D RESE L Sbjct: 1009 AEKEKISVLQNNYEKSQETFKQLQSDFYGRESELL 1043 Score = 36.2 bits (82), Expect = 1.2 Identities = 106/523 (20%), Positives = 204/523 (39%), Gaps = 54/523 (10%) Query: 365 DMPQLRSVKAQGQQQIVSS-ELNQDSVYSSVPLLSTIKGQKNR-RKTPDSKSKLSLNVPS 422 D ++++ K Q Q + +LN D + L ++ +K T K S + S Sbjct: 738 DSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALES 797 Query: 423 LKAKKTPTSQVFQITVCHTLKNRNE-LGCKNNTEKKELHERKDISDIALHLISVSKLILP 481 +K K T + QI LK E L + + +EL+ R + L + + K L Sbjct: 798 IKQKLTKQEEEKQI-----LKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALM 852 Query: 482 YVKNYSRKQLVKVMPGLIKCGHFLQKQNKSPDTEKINYAGPLEE------TGISDITKKE 535 + + +L KV L +K+N+ ++ +E + + K++ Sbjct: 853 TELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQ 912 Query: 536 KEYDKENKRLKNISPKMLPQLEQSFMVNTVQLKAPCLLVETNGKSKESLKDSITQAKGIG 595 KE K ++ K S ++ +L S +Q + ++ N K ++ L+ +I + K Sbjct: 913 KELKKSLEKEKEASHQLKLELN-SMQEQLIQAQNT---LKQNEKEEQQLQGNINELK--- 965 Query: 596 ITEFHVLNSKKPFDLHIPKHKTSLEEAISKPMQKLVSSPEMESNNRMKIQEDLQSSENSH 655 + K EA+ + K+ + E N+++ Q+ Q+++ Sbjct: 966 ---------------QSSEQKKKQIEALQGEL-KIAVLQKTELENKLQ-QQLTQAAQELA 1008 Query: 656 LQLSNGEELPTSTPKTQRCFPRENTQKQKDFLELVLELSNVGL-LISLGSKMHKSSEELE 714 + L + K+Q F Q Q DF EL L S+ K+ + E+L Sbjct: 1009 AEKEKISVLQNNYEKSQETFK----QLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLI 1064 Query: 715 AIKIQVNTESVNLKESKPLILNVTEDSDLRESEELE-CNTGSNITNMHQDKETSDAFHSA 773 + + Q+ ++ ++E K + +DS +E + E C +I KE + Sbjct: 1065 SNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKS 1124 Query: 774 TYTTISQLPDTETHSISK----AKADTLRIIR--LSHSASKQEKLPDEKETQ-NAEYIDK 826 I ++ + I+K K+ L I+ + +KQ + + E Q A+ + Sbjct: 1125 KLAEIEEIKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKA 1184 Query: 827 SCTFKKPQQCDRKEQEKEANSELTQGF---RFSIHLKQKPKYV 866 + +K Q K+Q K+ EL + F +H + K K V Sbjct: 1185 AVEQEKRNQQILKDQVKKEEEELKKEFIEKEAKLHSEIKEKEV 1227 Score = 36.2 bits (82), Expect = 1.2 Identities = 96/490 (19%), Positives = 197/490 (40%), Gaps = 72/490 (14%) Query: 3554 KICESILSLPHFKLNKETIDGVISSNVKSTKQHISQGKNDRVKAMDMKRIKSPNIILKPR 3613 +I ++ L K+ KE + +S+ VK +S + + + K IL Sbjct: 833 RIQTTVTELQKVKMEKEALMTELST-VKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLE 891 Query: 3614 KS--SLSHILSIKEFPLLLDIIKQEGKMQEGKGKSSMKLTNLCTSLPSLSHS--NSNSRT 3669 K+ L H L ++ + + +K++ ++++ K L L S+ + + Sbjct: 892 KTCKELKHQLQVQ----MENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTL 947 Query: 3670 KAGKDKSGTLKGCLPPLKLQASSNARRVSSAES------INRDSLSNVIESKCFP--QKK 3721 K + + L+G + LK + +++ + + + + L N ++ + Q+ Sbjct: 948 KQNEKEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQEL 1007 Query: 3722 KEDRENIVDVKDIMGLKCITLKGKKSLF----RHLLHGKEPQRSNKKLEKMTQEDE-SNL 3776 ++E I +++ T K +S F LL ++ +S ++ + QED SN Sbjct: 1008 AAEKEKISVLQNNYEKSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNR 1067 Query: 3777 NVVQNKLCASILSPPHLEWNPRIKEVYMRGITRFCLSSSTQQELSDTMEKCEQPIDDSLS 3836 N + N+ N I+E+ T S+ +Q+L E+C+ +L Sbjct: 1068 NQIGNQ-------------NKLIQELKTAKATLEQDSAKKEQQLQ---ERCK-----ALQ 1106 Query: 3837 SIEKAKHMPQKDKDRVEKALEKIMHSKRIALEVKQPSIFQELE---LNIKEKGGKIQEDK 3893 I+K K + +K+ +++ K E+++ QE E LN + K K++ K Sbjct: 1107 DIQKEKSLKEKE----------LVNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLESIK 1156 Query: 3894 EVEIWSKPFASISFLPYSKVGTIEGEEAMRIKMRSSFSQPNLQESSDTEKTAYEKCISDN 3953 E+ L + ++G+ A +K + N Q D K E+ + Sbjct: 1157 EIT----NLKDAKQLLIQQKLELQGK-ADSLKAAVEQEKRNQQILKDQVKKEEEELKKEF 1211 Query: 3954 ISNSVK-----KALESILQKEQRQKME---KIRALKKMKSSIS---QGIQLDIKEQEKRI 4002 I K K E ++K + + + +I AL + ++ Q Q + E EK+ Sbjct: 1212 IEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITALNENLGTVKKEWQSSQRRVSELEKQT 1271 Query: 4003 EHIKGEPSVL 4012 + ++GE +VL Sbjct: 1272 DDLRGEIAVL 1281 >gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo sapiens] Length = 1152 Score = 60.1 bits (144), Expect = 8e-08 Identities = 77/345 (22%), Positives = 147/345 (42%), Gaps = 68/345 (19%) Query: 3969 EQRQKMEKIRALKKMKSSISQGI---------------QLDIKEQEKRIEHIKG----EP 4009 ++ ++M +++ K K +SQGI +++I E+++ E KG E Sbjct: 545 DEYEEMSEMKEGKACKQHVSQGIFMTQPATTIEAFSDEEVEIPEEKEGAEDSKGNGIEEQ 604 Query: 4010 SVLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEAGEKADGVASKGD 4069 V + R+EK E +++ E+S K+ GE DG +GD Sbjct: 605 EVEANEENVKVHGG-------RKEKTEILSDDLTDKA-EVSEGKAKSVGEAEDGPEGRGD 656 Query: 4070 ITIKV-QKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKA-------KKALSQDLPLNTKE 4121 T + ++ Q +E ++ + + M +G K KK ++ +E Sbjct: 657 GTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKERE 716 Query: 4122 PG---KMDQEAQEQGKEDR------EGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQ 4172 G + +QE +E G+E+ EG+ + +E++ G G+E+ + E+ E G+ + E E+ Sbjct: 717 QGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVE-GEREKEEGER 775 Query: 4173 QKADGVGIEQ-GKMDGDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQ-GIIRPGIL 4230 +K + G E+ G+ +GD+ E E +T GEE ++ G + G + Sbjct: 776 KKEERAGKEEKGEEEGDQGEGEEE----------------ETEGRGEEKEEGGEVEGGEV 819 Query: 4231 QPRHQKSSETGKKANGVPSEGDSASEVQKAKDYMQQKEEDESKQE 4275 + + E ++ G EG+ E + ++EE E K E Sbjct: 820 EEGKGEREEEEEEGEGEEEEGEGEEEEGEG-----EEEEGEGKGE 859 Score = 54.7 bits (130), Expect = 3e-06 Identities = 37/156 (23%), Positives = 74/156 (47%), Gaps = 23/156 (14%) Query: 4123 GKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGK---MDHEVEEQQKADGVG 4179 G+ ++E E E+ EGE +G+E+ G G+E ++E+G+ + E EE+ + +G G Sbjct: 946 GEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEG 1005 Query: 4180 IEQGKMDGDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSSE 4239 E+G+ +G++ E+ V + +EGEE + G + ++ E Sbjct: 1006 EEEGEGEGEEEEEGEV----------------EGEVEGEEGE----GEGEEEEGEEEGEE 1045 Query: 4240 TGKKANGVPSEGDSASEVQKAKDYMQQKEEDESKQE 4275 K+ G + + E ++ Y + EE+ +Q+ Sbjct: 1046 REKEGEGEENRRNREEEEEEEGKYQETGEEENERQD 1081 Score = 49.3 bits (116), Expect = 1e-04 Identities = 48/217 (22%), Positives = 92/217 (42%), Gaps = 29/217 (13%) Query: 4059 EKADGVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPLN 4118 EK +G K + K +K ++ Q E +E + + + E+ G + + Sbjct: 769 EKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGE--EKEEGGEVEGGEVEEGKGER 826 Query: 4119 TKEPGKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADGV 4178 +E + + E +E E+ EGE + +E +E + E +E+G+ E+++ +G Sbjct: 827 EEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGE 886 Query: 4179 GIEQGKMDGDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSS 4238 G E+G+ +G++ E E EGEE+ +G G + K Sbjct: 887 GEEEGEGEGEEEEGEG---------------------EGEEEGEG---EGEEEEGEGKGE 922 Query: 4239 ETGKKANGVPSEGDSASEVQKAKDYMQQKEEDESKQE 4275 E G++ G EG+ + +D + EE+E + E Sbjct: 923 EEGEEGEG---EGEEEEGEGEGEDGEGEGEEEEGEWE 956 Score = 47.8 bits (112), Expect = 4e-04 Identities = 92/455 (20%), Positives = 183/455 (40%), Gaps = 56/455 (12%) Query: 3917 EGEEAMRIKMRSSFSQPNLQESSDTEKTAYEKCISDNISNSVKKALESILQKEQRQKMEK 3976 E E+ + K R +P E EK ++K + +K E QKE+ Q+ME+ Sbjct: 673 EREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEE---QEQKEREQGHQKERNQEMEE 729 Query: 3977 IRALKKMKSSISQGIQLDIKE------QEKRIEHIKGEPSVLLTNACASIPSPSHLQLDT 4030 + + +G + + +E +E E ++GE + + + Sbjct: 730 GGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEE 789 Query: 4031 RREKAEYVTEITRYYLPELSHQKSSEAGEKADGVASKGDITIKVQKAKDYMQQKEDDEVK 4090 ++ E E T E E GE +G KG+ + ++ + ++ E +E + Sbjct: 790 EGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEG---KGEREEEEEEGEGEEEEGEGEEEE 846 Query: 4091 ISAKKDIMHP--EDKGLKAKKALSQDLPLNTKEPGKMDQEAQEQGK---EDREGEEQGKE 4145 +++ E++G + + + E + + E +E+G+ E+ EGE +G+E Sbjct: 847 GEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEE 906 Query: 4146 DRRGAGQE-----KVDREDKE-QGKMDHEVEEQQKADGVGI---EQGKMDGDKNEQERVL 4196 + G G+E K + E +E +G+ + E E + DG G E+G+ +G++ E E Sbjct: 907 EGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEG-- 964 Query: 4197 FLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSSETGKKANGVPSEGDSASE 4256 EGEE+ +G G + ++ G++ G EG+ E Sbjct: 965 -------------------EGEEEGEGEGEEGEGEGEEEEGEGEGEEEEG-EEEGEEEGE 1004 Query: 4257 VQKAKDYMQQKEEDESKQETVLFLHLPSESSLTCYELNTRKEGEEDLQGIIKSATLQLRQ 4316 ++ + ++EE+ + V E E +EGEE + + R+ Sbjct: 1005 GEEEGEGEGEEEEEGEVEGEVEGEEGEGEGE----EEEGEEEGEEREKEGEGEENRRNRE 1060 Query: 4317 QKSFDAGKIAHTKSFGVDSSNDVKTVQEYKPQKEV 4351 ++ + GK T + N+ + +EYK ++ Sbjct: 1061 EEEEEEGKYQETG----EEENERQDGEEYKKVSKI 1091 Score = 47.8 bits (112), Expect = 4e-04 Identities = 36/155 (23%), Positives = 76/155 (49%), Gaps = 25/155 (16%) Query: 4123 GKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADGVGIEQ 4182 G+ ++E E E+ EGEE+G+E+ G + + + E++E+G+++ EVE ++ E+ Sbjct: 979 GEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEE 1038 Query: 4183 GKMDGDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSSETGK 4242 G+ +G++ E+E EGEE+++ + K ETG+ Sbjct: 1039 GEEEGEEREKEG---------------------EGEENRRNREEE---EEEEGKYQETGE 1074 Query: 4243 KANGVPSEGDSASEVQKAKDYMQQKEEDESKQETV 4277 + N +G+ +V K K ++ + ++++V Sbjct: 1075 EEN-ERQDGEEYKKVSKIKGSVKYGKHKTYQKKSV 1108 Score = 39.3 bits (90), Expect = 0.14 Identities = 34/131 (25%), Positives = 67/131 (51%), Gaps = 15/131 (11%) Query: 4120 KEPGKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADGVG 4179 +E G+ + E +E+G+ + E EE+G+ + G+E ++E+G + E EE++K +G G Sbjct: 996 EEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEG--EEEGEEREK-EGEG 1052 Query: 4180 IEQGKMDGDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQ-GIIRPGILQPRH---Q 4235 E+ + + ++ E+E + + R +GEE ++ I+ + +H Q Sbjct: 1053 -EENRRNREEEEEEEGKYQETGEEE-------NERQDGEEYKKVSKIKGSVKYGKHKTYQ 1104 Query: 4236 KSSETGKKANG 4246 K S T + NG Sbjct: 1105 KKSVTNTQGNG 1115 >gi|13540523 nucleosomal binding protein 1 [Homo sapiens] Length = 282 Score = 59.3 bits (142), Expect = 1e-07 Identities = 63/217 (29%), Positives = 101/217 (46%), Gaps = 57/217 (26%) Query: 4083 QKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPLNTKEPGKMDQEAQ-----EQGKEDR 4137 +KE EVK +++I +KG + K+A++ ++ N +E K D+E Q E GKED+ Sbjct: 94 EKEIVEVK---EENIEDATEKGGEKKEAVAAEVK-NEEEDQKEDEEDQNEEKGEAGKEDK 149 Query: 4138 E--GEEQGKEDRRG--AGQEKVDRED--------------KEQGKMDHEVEEQQKA-DGV 4178 + GEE GKED+ G G++ ++ED KE+G+ + E E++++ DG Sbjct: 150 DEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGK 209 Query: 4179 GIEQGKMDGDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSS 4238 E GK GDK E + V R +G+ED+ G Sbjct: 210 ENEDGKEKGDKKEGKDVKVKEDEKE----------REDGKEDEGG------------NEE 247 Query: 4239 ETGKKANGVPSEGDSASEVQKAKDYMQQKEEDESKQE 4275 E GK E + E ++ K+ + KE+D K+E Sbjct: 248 EAGK-------EKEDLKEEEEGKEEDEIKEDDGKKEE 277 Score = 48.5 bits (114), Expect = 2e-04 Identities = 50/222 (22%), Positives = 93/222 (41%), Gaps = 59/222 (26%) Query: 4054 SSEAGEKADGVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQ 4113 + + GEK + VA++ K+ + +++DE + +K EDK K ++ + Sbjct: 109 TEKGGEKKEAVAAE---------VKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKE 159 Query: 4114 DLPLNTKEPGKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQ 4173 D N K ++E ++G++ + E GKE G+++ + ED+ ++ Sbjct: 160 DKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKE----KGEDEKEEEDR-----------KE 204 Query: 4174 KADGVGIEQGKMDGDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQPR 4233 DG E GK GDK E + D +++ +E Sbjct: 205 TGDGKENEDGKEKGDKKEGK------------------DVKVKEDE-------------- 232 Query: 4234 HQKSSETGKKANGVPSEGDSASEVQKAKDYMQQKEEDESKQE 4275 K E GK+ G +E ++ E + K+ + KEEDE K++ Sbjct: 233 --KEREDGKEDEG-GNEEEAGKEKEDLKEEEEGKEEDEIKED 271 Score = 47.0 bits (110), Expect = 7e-04 Identities = 42/149 (28%), Positives = 71/149 (47%), Gaps = 33/149 (22%) Query: 4051 HQKSSEAGEKADGVAS---KGDITIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKA 4107 ++K +A EK DG KG+ +K +D +KE+++ K + D ED K Sbjct: 164 NEKGEDAKEKEDGKKGEDGKGNGEDGKEKGED---EKEEEDRKETG--DGKENEDGKEKG 218 Query: 4108 KKALSQDLPLNTKEPGKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDH 4167 K +D+ + K D++ +E GKED G E+ AG+EK D +++E+GK + Sbjct: 219 DKKEGKDVKV------KEDEKEREDGKEDEGGNEEE------AGKEKEDLKEEEEGKEED 266 Query: 4168 EVEEQQKADGVGIEQGKMDGDKNEQERVL 4196 E++E DG K E + ++ Sbjct: 267 EIKED-------------DGKKEEPQSIV 282 Score = 35.0 bits (79), Expect = 2.6 Identities = 56/260 (21%), Positives = 102/260 (39%), Gaps = 48/260 (18%) Query: 4073 KVQKAKDYMQQKEDDEVKISA--KKDIMHPEDKGLKAK--KALSQDLPLNTKEPGKMDQE 4128 K++ D M++ D + A K++ + ED AK +A + P + KE E Sbjct: 44 KMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEI----VE 99 Query: 4129 AQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEE----QQKADGVGIEQGK 4184 +E+ ED E+ G++ A + K + ED+++ + D E+ ++ D G E GK Sbjct: 100 VKEENIEDAT-EKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGK 158 Query: 4185 MDGDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSSETGKKA 4244 D + NE+ + E E+ ++G G + E GK+ Sbjct: 159 EDKNGNEKG------------------EDAKEKEDGKKGEDGKG--------NGEDGKEK 192 Query: 4245 NGVPSEGDSASEVQKAKDYMQQKEEDESKQETVLFLHLPSESSLTCYELNTRKEGEEDLQ 4304 E + E K+ KE+ + K+ + + R++G+ED Sbjct: 193 GEDEKEEEDRKETGDGKENEDGKEKGDKKE---------GKDVKVKEDEKEREDGKEDEG 243 Query: 4305 GIIKSATLQLRQQKSFDAGK 4324 G + A + K + GK Sbjct: 244 GNEEEAGKEKEDLKEEEEGK 263 >gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] Length = 1020 Score = 58.2 bits (139), Expect = 3e-07 Identities = 139/765 (18%), Positives = 298/765 (38%), Gaps = 61/765 (7%) Query: 3443 KLRLGKKIETQKANEKVQKEVCLPITLH--SLSASMPILQESKGQKDSVEQVIRKGVICH 3500 ++RL + E K N + IT + L A L+ K KDS+E+ + H Sbjct: 294 RVRLDRLSEAAKVNTDAMRSAQEEITEYRRQLQARTTELEALKSTKDSLERQRSELEDRH 353 Query: 3501 KRRTSKWKKSVFSHILNTSDCGASSNRLEMQWNMTD--KMVNVKHRMSEIDLVAAKICES 3558 + + +++++ D + + EM + + ++NVK + +I++ A + Sbjct: 354 QADIASYQEAI-----QQLDAELRNTKWEMAAQLREYQDLLNVKMAL-DIEIAAYR---K 404 Query: 3559 ILSLPHFKLNKETIDGVISSN---VKSTKQHISQGKNDRVKAMDMKRIKSPNIILKPRKS 3615 +L ++ I + + S HI +++K ++ ++ + + ++ Sbjct: 405 LLEGEECRIGFGPIPFSLPEGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEET 464 Query: 3616 SLSHILSIKEFPLLLDIIKQEGKMQEGKGKSSMKLTNLCTSLPSLSHSNSNSRTKAG--K 3673 ++ ++ +E + ++EGK +EG + + T P + S + K Sbjct: 465 QVTEEVTEEEEK---EAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVK 521 Query: 3674 DKSGTLKGCLPPLKLQASSNARRVSSAESINRDSLSNVIESKCFPQKKKEDRENIVDVKD 3733 +++ + P K +A S A V S E + E+K P+ K ++E + Sbjct: 522 EEAKSPAEAKSPEKEEAKSPAE-VKSPEKAKSPAKE---EAKSPPEAKSPEKEEAKSPAE 577 Query: 3734 IMGLKCITLKGKKSLFRHLLHGKEPQRSNKKLEKMTQEDESNLNVVQNKLCASILSPPHL 3793 + + + KS + +S +K + +E+ + ++ + SP + Sbjct: 578 VK-----SPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEV 632 Query: 3794 EWNPRIKEVYMRGITRFCLSSSTQQELSDTMEKCEQPIDDSLSSIEKAKHMPQKDKDRVE 3853 + + K + S ++E + + EK + P+ S EKAK + + E Sbjct: 633 KSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPE 692 Query: 3854 KALEKIMHSKRIALEVKQPSIFQELELNIKEKGGKIQEDKEVEIWSKPFASISFLPYSKV 3913 KA + + + K P + +E + K K +E K E P + P Sbjct: 693 KAKSPVKEEAKSPEKAKSP-VKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAK 751 Query: 3914 GTIEGEEAMRIKMRSSFSQPNLQESSDTEKTAYEKCISDNISNSVK--KALESILQKEQR 3971 E+A + ++S ++ +E + + + + + VK + +S L+++ + Sbjct: 752 SP---EKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAK 808 Query: 3972 QKMEKIRALKKMKSSISQGIQLDIKEQEKRIEHIKGEPSVLLTNACASIPSPSHLQLDTR 4031 ++I +++KS + KE+EK E EP A + + D++ Sbjct: 809 APEKEIPKKEEVKSPV--------KEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSK 860 Query: 4032 REKAEYVT----EITRYYLPELSHQKSSEAGEKADGVASKGDITIKVQKAKDYMQQKEDD 4087 +E+A ++ P + K S+ K + K + ++A ++ KED Sbjct: 861 KEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDA 920 Query: 4088 EVKISAKKDIMHPEDKGLKAKKALSQDLPLNTKE--PGKMD--QEAQEQGKEDREGEEQG 4143 + K + P+D KA P KE P K D +E ++ +E + E + Sbjct: 921 KPKEKTEVAKKEPDD-----AKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKA 975 Query: 4144 KEDRRGAGQE----KVDREDKEQGKMDHEVEEQQKADGVGIEQGK 4184 KED + +E K ++ +K + + +KA +GK Sbjct: 976 KEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATEDKAAKGK 1020 Score = 42.4 bits (98), Expect = 0.016 Identities = 102/497 (20%), Positives = 188/497 (37%), Gaps = 64/497 (12%) Query: 3835 LSSIEKAKHMPQKDKDRVEKALEKIMHSKRIALEVKQPSIFQELELNIKEKGGKIQEDKE 3894 + S EK K + + +K+ V +E+ ++ EV + + E KE+ G +E+ E Sbjct: 438 VKSEEKIKVVEKSEKETV--IVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAE 495 Query: 3895 --VEIWSKPFASISFLPYSKVGTIEGEEAMRIKMRSSFSQPNLQES-SDTEKTAYEKCIS 3951 E P A + P + + EEA K + P +E+ S E + EK S Sbjct: 496 GGEEETKSPPAEEAASPEKEAKSPVKEEA---KSPAEAKSPEKEEAKSPAEVKSPEKAKS 552 Query: 3952 DNISNSVKKALESILQKEQRQKMEKIRALKKMKSSISQGIQ--LDIKEQEKRIEHIKGEP 4009 + +KE+ + ++++ +K KS + + + K EK +K E Sbjct: 553 PAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEA 612 Query: 4010 SVLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEAGEKADGVASKGD 4069 + A A P + + E T+ KS E E +K Sbjct: 613 K---SPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSP 669 Query: 4070 ITIKV---QKAKDYM--QQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDL--PLNTKEP 4122 + + +KAK + + K ++ K K++ PE KAK + ++ P K P Sbjct: 670 VKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPE----KAKSPVKEEAKSPEKAKSP 725 Query: 4123 ----GKMDQEAQEQGKEDREGEEQGK-------------EDRRGAGQEKVDREDKEQGKM 4165 K ++A+ KE+ + E+ K E + A +E DK K Sbjct: 726 VKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKA 785 Query: 4166 DHEVEEQQKADGVGIEQGKMDGDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQGII 4225 V+E+ K+ K D E+E +P + + E E+ Q+ + Sbjct: 786 KSPVKEEVKSPEKAKSPLKEDAKAPEKE------IPKKEEVKSPVK----EEEKPQEVKV 835 Query: 4226 RPGILQPRHQKSSETGKKANGVPSEGDSASEVQKAKDYMQQKEEDESKQETVLFLHLPSE 4285 + + +K+ T K S+ + A + + K +++K+E ++ P E Sbjct: 836 KEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEK--------PKE 887 Query: 4286 SSLTCYELNTRKEGEED 4302 S ++ +KE ED Sbjct: 888 S-----KVEAKKEEAED 899 Score = 38.5 bits (88), Expect = 0.23 Identities = 48/252 (19%), Positives = 103/252 (40%), Gaps = 21/252 (8%) Query: 3957 SVKKALESILQKEQRQKMEKIRALKKMKSSISQGIQLDIKEQEKRIEHIKGEPSVL---- 4012 S ++A++ + + + K E L++ + ++ + LDI+ R + ++GE + Sbjct: 359 SYQEAIQQLDAELRNTKWEMAAQLREYQDLLNVKMALDIEIAAYR-KLLEGEECRIGFGP 417 Query: 4013 ----LTNACASIPSPS-HLQLDTRR-----EKAEYVTEITRYYLPELSHQKSSEAGEKAD 4062 L IPS S H+++ + EK+E T I E + E+ + Sbjct: 418 IPFSLPEGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKE 477 Query: 4063 GVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPLNTKEP 4122 +G + + ++ + ++E K ++ PE + K ++ P K P Sbjct: 478 AKEEEGK---EEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKS-PAEAKSP 533 Query: 4123 GKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADGVGIEQ 4182 K + ++ + K + + KE+ + + K +KE+ K EV+ +KA E+ Sbjct: 534 EKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAK--SPEKEEAKSPAEVKSPEKAKSPAKEE 591 Query: 4183 GKMDGDKNEQER 4194 K + E+ Sbjct: 592 AKSPAEAKSPEK 603 Score = 38.5 bits (88), Expect = 0.23 Identities = 48/223 (21%), Positives = 96/223 (43%), Gaps = 12/223 (5%) Query: 6055 PQPFAVDKQQMQKLPNVKSEANLRSEMNKKYLKAQTKERIVPEHDVSRIIKKPDLRIIEQ 6114 P PF++ + + K+P+V + ++SE K ++ KE ++ E + + E+ Sbjct: 417 PIPFSLP-EGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEE--TQVTEEVTEE 473 Query: 6115 EEKILKRILTPTECPSMLEDPKLPKQRDQSEPVWDMTTQKVQQQKAFPGTVPIPPQVKS- 6173 EEK K E E+ + ++ +S P + + + + + P + KS Sbjct: 474 EEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSP 533 Query: 6174 --SEVKIVADSTNAEHL-LPICEATKAISESQVKNMIQDKVSSDKLDNIQAYKP--DDLK 6228 E K A+ + E P E K+ E++ + K ++ +A P ++ K Sbjct: 534 EKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAK 593 Query: 6229 SPPFPEGPDTISTAIYPKTQHKSLLEQFTP-KEKNKLTSHLES 6270 SP + P+ + + K + KS E +P KE+ K + ++S Sbjct: 594 SPAEAKSPEKAKSPV--KEEAKSPAEAKSPVKEEAKSPAEVKS 634 >gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] Length = 2230 Score = 57.0 bits (136), Expect = 6e-07 Identities = 107/552 (19%), Positives = 221/552 (40%), Gaps = 83/552 (15%) Query: 3818 QELSDTMEKCE----QPIDDSLSSIEKAKHMPQKDKDRVE---KALEKIMHSKRIALEVK 3870 +EL + EK E + ++ +LS+ +K + +K K ++ K +EK +RI+L+ + Sbjct: 399 EELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQE 458 Query: 3871 QPSIFQELELNIKEKGGKIQEDKEVEIWSKPFASISFLPYSKVGTIEGE--EAMRIKMRS 3928 + QE+ +++ +K + Q K ++ K A K+ T E E E M++ + Sbjct: 459 LSRVKQEV-VDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEK 517 Query: 3929 SFSQ--PNLQESSDTEKTAYE------KCISDNISNSVK-----------------KALE 3963 S S+ QE E A E K I N ++ +LE Sbjct: 518 SQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLE 577 Query: 3964 SILQKEQRQKMEKIRALKKMKSSISQGIQLDIKEQEKRIEHIKGEPSVLLTNACASIPSP 4023 LQ+ + Q + L+ K+ ++ I + +++ + +E +K + L T + Sbjct: 578 KSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQ 637 Query: 4024 SHLQLDTRREKAEYVTEITRYYLPELSHQKSSEAGEKADGVASKGDITIKVQKAKDYMQQ 4083 +++ REK E + E K + + I +K + + Sbjct: 638 YQTEMEKLREKCE----------------QEKETLLKDKEIIFQAHIEEMNEKTLEKLDV 681 Query: 4084 KEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPLNTKEPGKMDQEAQEQGKEDREGEEQG 4143 K+ + +S++ + LKA+ L ++L + + KM QE + + E + +Q Sbjct: 682 KQTELESLSSELSEV------LKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQ 735 Query: 4144 KEDRRGAGQEKVDREDKE------------QGKMDHEVEEQQKADGVGIEQGKMDGDKNE 4191 + + + R +K + + H E Q + + + + +G+ + Sbjct: 736 VDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQ 795 Query: 4192 QERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSSETGKKANGVPSEG 4251 L ++ S S TH + + E+Q ++ +L ++ T + A + Sbjct: 796 ASAKLDVF-QSYQSATH----EQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKK 850 Query: 4252 DSASEVQ----KAKDYMQQKEEDESKQE-TVLFLHLPSESSLTCYELNTRKEGEEDLQGI 4306 D +E+ + +D MQQ E+ S+ E V L ES L + KE E+ Q + Sbjct: 851 DVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLE----DGNKEQEQTKQIL 906 Query: 4307 IKSATLQLRQQK 4318 ++ + L+ ++ Sbjct: 907 VEKENMILQMRE 918 Score = 53.5 bits (127), Expect = 7e-06 Identities = 191/978 (19%), Positives = 380/978 (38%), Gaps = 143/978 (14%) Query: 2227 TMKEKKSSISQIHKINRESTRKHRKKCKSYLKTVSNRKCQENHGHITEEEEEVQENSPAT 2286 T++++ + K +E+ + H+++C L T QE +E E++++ Sbjct: 283 TLQQRVKRQENLLKRCKETIQSHKEQCT--LLTSEKEALQEQLDERLQELEKIKD----L 336 Query: 2287 FLGPLDFFMPVLSDSKNQINTIQLSERKIILNPKCL---TMKEKKPPISQIHKISRQFTT 2343 + + L D+KN I ++ + +I K T++ K+ I+Q+ +Q TT Sbjct: 337 HMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTT 396 Query: 2344 KHRKKLESNLKTKLKAMWQGENVADTFPNTTSFTPDSSDIKRQSGFQTEIDMRISGLSHT 2403 + + E K++ A + E T T + +R+ + E+D +I + T Sbjct: 397 QGEELREQKEKSERAAFEELEKALSTAQKT-------EEARRK--LKAEMDEQIKTIEKT 447 Query: 2404 QPTQIESLAEGIARYS----DPIDKRRTSNLVKGAKLHDRESGEEKQE---HLTEMDPFY 2456 + SL + ++R D + K + K KLH++E ++QE L + + Sbjct: 448 SEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREF 507 Query: 2457 AENFMA------NTYLRKDRHLGKSEDVLLGETFFSKSQIYKGNSEKNVKIEKNKNGKES 2510 E + YL+ + + E + L E K I +E K+ + E+ Sbjct: 508 QEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAIL---TESENKLRDLQQEAET 564 Query: 2511 LKVGLARMEKSDNCAELSEATDDAISNKYDKQNIGHSVLKENAFCNLAAIVPDSVGRHSP 2570 + + +E S L ++ + NK +++ + E N V V +H Sbjct: 565 YRTRILELESS-----LEKSLQE---NKNQSKDLAVHLEAEKNKHNKEITV--MVEKHKT 614 Query: 2571 ASEEMKRQNGRL-----------KMADRSSPQGRPLQAKQSAVSQSPDTAGYAVVSNNKE 2619 E +K Q L + + + Q K++ + + N++ Sbjct: 615 ELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEK 674 Query: 2620 QKQNFKAQKTEAEVDLIDQEAKINVAEEFNPESVFFSKIHPLQIENKKEFKTADWKTRAD 2679 + ++TE E L + +++ A E + K +++ + E K + K Sbjct: 675 TLEKLDVKQTELE-SLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQ 733 Query: 2680 PKTFALPKKQQELCVSGTIWSYPNPYTSISPKIIRHKDK------AKTADVESTMHTKQI 2733 + ++ K+ E+ + T + + + +++ +DK A ++E+ + + Sbjct: 734 QQVDSI-IKEHEVSIQRTEKALKDQINQLE-LLLKERDKHLKEHQAHVENLEADIKRSEG 791 Query: 2734 KLKAKRIPVSQLLEYGTASNKKELRGNIQ----QQKSFQLSKNAVHRVLKAVYDSGYCVS 2789 +L+ + Y +A++++ Q QQK L + + K V + V Sbjct: 792 ELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERI-LLTKQVAE----VE 846 Query: 2790 SIKKLTEVKMEKDKPKDRTCILPQPKLEKPLKEMQRSLSGCTDMSSILRKQEQDIREKEQ 2849 + KK +V E D K + L Q +LEK EM++ + T + K E +E+EQ Sbjct: 847 AQKK--DVCTELDAHKIQVQDLMQ-QLEKQNSEMEQKVKSLTQVYE--SKLEDGNKEQEQ 901 Query: 2850 KHQSISED---ISQYYIG---PLRISSQQINYSSFDAPRIRTDEELEF--------LIAQ 2895 Q + E I Q G + I +Q+++ + + E +F + Q Sbjct: 902 TKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQ 961 Query: 2896 RAKEKDVGIAKH-----------------SVSIPWEREGSKRLDI-PLNSKGQNIFFTEL 2937 +AKE + K +S ++ +K L++ NS G + + L Sbjct: 962 KAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRL 1021 Query: 2938 DTSQQKICQ------EQELLKQEDISMTNLGSMACPIMEPLHLENTGKVTEEEDVYINRK 2991 +T+Q++ + +EL I L A + E ++ K E+E + +K Sbjct: 1022 ETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEK--EQEVAELKQK 1079 Query: 2992 ISSHVLGKEGLKETDIFVGSKGQKFLCTNSEVQHKVPAEQKEQVNPDHVPESILDSESFL 3051 I KE + + ++ +G K T +E+Q ++ +QK HV S+ E+ L Sbjct: 1080 ILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQL--KQKSA----HV-NSLAQDETKL 1132 Query: 3052 SKDPLHLKQAVNTARKENVTISESFNENLWGKEQSKLDI---------------TLKSNR 3096 L+ +N + KEN + E E E+ K + +LKS+ Sbjct: 1133 KAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSH 1192 Query: 3097 QKMDFS---KKLRMKHLS 3111 +K + S K L K LS Sbjct: 1193 EKSNKSLEDKSLEFKKLS 1210 Score = 52.4 bits (124), Expect = 2e-05 Identities = 317/1658 (19%), Positives = 618/1658 (37%), Gaps = 274/1658 (16%) Query: 1599 EKKETAIFGSCMPALSTPKTT----RNLKQFSDMKTLVNPKCGIIKAKKPSISYMLNIRA 1654 EK E A F ALST + T R LK D + K + ++ S+ L+ Sbjct: 406 EKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTS--EEERISLQQELSRVK 463 Query: 1655 GAGPKRRKELSCNLTTKMKELHQ---GKKGVDETYAFLTMTPDINKYSKVETEKDTLREK 1711 K+ S K+++LH+ +K + T T + + KV EK Sbjct: 464 QEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYL 523 Query: 1712 RLSSTQVKQDTSPHEDSITSRDI----KETLLQDEEQEERKQEPLLKVIPQHLQHFMFRS 1767 ++S + +Q++ E+ + E L+D +QE + + L+ + + Sbjct: 524 KISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQEN 583 Query: 1768 -GQGKDLDFHKLENQGSRKILFVTKQDVPQQLQPAEPIQREETK-KCLQTQNGTICTVNS 1825 Q KDL H LE + ++ +T +++ +T+ + L+ Q + T Sbjct: 584 KNQSKDLAVH-LEAEKNKHNKEITVM-----------VEKHKTELESLKHQQDALWT--E 629 Query: 1826 KLLPLKSEDSVNGEVLTGAIKRGVPTDRKCMGEQHNSGKGEKAEFNKDLQATVLELQKSP 1885 KL LK + E L KC E+ K ++ F QA + E+ + Sbjct: 630 KLQVLKQQYQTEMEKLR----------EKCEQEKETLLKDKEIIF----QAHIEEMNEKT 675 Query: 1886 HGGEAQKANLTDMESGSSNAMN-MNVQHEREDKNIQKMLTESVPCYSQHLRFSTHQMKDP 1944 E T++ES SS + +H+ E++ +L + Q L + K+ Sbjct: 676 L--EKLDVKQTELESLSSELSEVLKARHKLEEE--LSVLKDQTDKMKQELEAKMDEQKNH 731 Query: 1945 DPCKSGSEPKSPEGRSWNLSHIVQKTKQETHFRETVLEPISGYMMKQSPHMQEGIKCMEG 2004 + S K E +Q+T++ + LE + + ++ H++E +E Sbjct: 732 HQQQVDSIIKEHEVS-------IQRTEKALKDQINQLELL---LKERDKHLKEHQAHVEN 781 Query: 2005 LKTSFPKT-GKSKIGSIPRDTPWDENPRRKWDSSISQKT-AWNQKNLQTVLKPLDFSSLM 2062 L+ ++ G+ + S D + + S+ ++T A+ ++ Q K LD + Sbjct: 782 LEADIKRSEGELQQASAKLDV------FQSYQSATHEQTKAYEEQLAQLQQKLLDLET-- 833 Query: 2063 SSEYESRSYTLEFIGKKSMSPK--CVTLKAKQLRILQLFNII-RYSTENHRKKKQHRFKY 2119 R + + + K C L A ++++ L + + ++E +K K Y Sbjct: 834 -----ERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVY 888 Query: 2120 KMK----------GKQWYTSIGEALLSATEYAKSTTSKSMIDKLLYNTAARCILSNR--T 2167 + K KQ +L E K + + KL + IL+ T Sbjct: 889 ESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEI-EILTQKLSAKEDSIHILNEEYET 947 Query: 2168 RRQNLDGHITEEKEEVQENVAAIFLGLLDFFMPVLSDSKNQRNTA-QLSEKEIIFNAKCL 2226 + +N + + + K++ +E + LLD + K NTA +LS+KE FNAK L Sbjct: 948 KFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKL---KKELENTALELSQKEKQFNAKML 1004 Query: 2227 TMKEKKSS-----ISQIHKINRES----TRKHRKKCKSYLKTVSNRKCQENHGHITEEEE 2277 M + S+ +S++ +E T HR++ + + + ++ E Sbjct: 1005 EMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKK--------LNQQAE 1056 Query: 2278 EVQENSPATFLGPLDFFMPVLSDSKNQINTIQLSERKIILNPKCLTMKEKKPPISQIHKI 2337 E+QE I+ IQL E++ + E K I Sbjct: 1057 ELQE-----------------------IHEIQLQEKE-------QEVAELKQKILLFGCE 1086 Query: 2338 SRQFTTKHRKKLESNLKTKLKAMWQGENVADTFPNTTSFTPDSSDIKRQSGFQTEIDMRI 2397 + + E +K E + + S D + +K + E+D+ Sbjct: 1087 KEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLE-KLEVDLNK 1145 Query: 2398 SGLSHT----QPTQIESLAEGIARYSDPIDKRRTSNLVKGAKLHDRE-----SGEEKQEH 2448 S +T Q +++ LAE DKR+ S L K D E S EK Sbjct: 1146 SLKENTFLQEQLVELKMLAEE--------DKRKVSELTSKLKTTDEEFQSLKSSHEKSNK 1197 Query: 2449 LTEMDPFYAENFMANTYLRKDRHLGKSEDVLLGETFFSKSQIYKGNSEKNVKI------- 2501 E + ++ D K+E +L +T +++ +S K I Sbjct: 1198 SLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKT----NELINISSSKTNAILSRISHC 1253 Query: 2502 -EKNKNGKESLKVGLARMEKSDNCAELSEATDDAISNKYDKQNIGHSV-LKENAFCNLAA 2559 + KE+L + + + + A+L + T++ + Q H + KEN ++ A Sbjct: 1254 QHRTTKVKEALLIKTCTVSELE--AQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKA 1311 Query: 2560 IVPDSVGRHSPASEEMKRQNGRLKMADRSSPQGRPLQAKQSAVSQSPD--TAGYAVVSNN 2617 + V E ++++ G Q + K+S ++Q + V+ Sbjct: 1312 DIESLV----TEKEALQKEGGN---------QQQAASEKESCITQLKKELSENINAVTLM 1358 Query: 2618 KEQKQNFKAQKTEAEVDLIDQEAKINVAEEFNPESVFFSKIHPLQIENKKEFKTADWKTR 2677 KE+ + K + + L D ++ + + + S + E K E D Sbjct: 1359 KEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCEL--LDQVQD 1416 Query: 2678 ADPKTFALPKKQQELCVSGTIWS--YPNPYTSISPKIIRHKDKAKTADVESTMHTKQIKL 2735 K L K++ WS + + +H++ K ++ + +K+ Sbjct: 1417 LSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYE 1476 Query: 2736 KAKRIPVSQLLEYGTASNKKE--LRGNIQQQKSFQLSKNA---------VHRVLKAVYDS 2784 K ++I + L E NK+ L+G ++ KS K + R+++ Sbjct: 1477 KDEQI--NLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHI 1534 Query: 2785 GYCVSSIKKLTEVKMEKDKPKDRTCILPQPKLEKPLKEMQRSLSGCTDMSSILRKQEQDI 2844 I+ L EV ++ KD + +L + L+ Q +E+D Sbjct: 1535 TQKTIEIESLNEVLKNYNQQKD----IEHKELVQKLQHFQE------------LGEEKDN 1578 Query: 2845 REKEQKHQSISEDISQYYIGPLRISSQQINYSSFDAPRIRTDEELEFL------------ 2892 R KE + + ++ + +Q Y + +++ + +EEL+ L Sbjct: 1579 RVKEAEEKILTLE-NQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKL 1637 Query: 2893 --IAQRAKEKDVGIAKHSVSIPWEREGSKRLDIPLNSKGQNIFFTELDTSQQKICQEQEL 2950 + ++A++K I K +S E+E + KG +EL+T Q+ +E + Sbjct: 1638 AELKRKAEQKIAAIKKQLLSQMEEKEEQYK-------KGTESHLSELNTKLQEREREVHI 1690 Query: 2951 LKQEDISMTNLGSMACPIMEPLHLENTGKVTEEEDV--------YINRKIS---SHVLGK 2999 L+++ S+ + S + ++ P +N TE+E+ KIS ++ K Sbjct: 1691 LEEKLKSVES--SQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEK 1748 Query: 3000 EGLKETDIFVGSKGQKFLCTNSEVQHKVPAEQKEQVNPDHVPESILDSESFLSKDPLHLK 3059 E L + VG + ++ + ++ E++ + Q+ + +H + +S + HL+ Sbjct: 1749 EKLLQR---VGQEKEETVSSHFEMRCQY---QERLIKLEHAEAKQHEDQSMIG----HLQ 1798 Query: 3060 QAVNTARKENVTISESFNENLWGKEQSKLDITLKSNRQKM--DFSKKLRMKHLSNYYQNK 3117 + + K+ I E KE K +I K N + + D K L+ K L+ Q Sbjct: 1799 EELEEKNKKYSLIVAQHVE----KEGGKNNIQAKQNLENVFDDVQKTLQEKELT--CQIL 1852 Query: 3118 ENILESVLPCILHQLYIENPKKEGSAEEIMSSKVLSPM 3155 E ++ + C++ Q + + E + + L M Sbjct: 1853 EQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQM 1890 Score = 49.3 bits (116), Expect = 1e-04 Identities = 336/1890 (17%), Positives = 689/1890 (36%), Gaps = 300/1890 (15%) Query: 2487 KSQIYKGNSEKNVKIEKNKNGKESLKVGLARMEKSDNCAELSEATDDAISNKYDKQNIGH 2546 K +G + K + + E L+ L+ +K++ +A D +K + Sbjct: 392 KQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEE 451 Query: 2547 SVLKENAFCNLAAIVPDSVGRHSPASEEMKRQNGRLKMADRSSPQGRPLQAK------QS 2600 + + + V D + + S ++ ++A + + LQ + Q Sbjct: 452 RISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQM 511 Query: 2601 AVSQSPDTAGYAVVSNNKEQKQNFKAQKTEAEVDLIDQEAKINVAEEFNPESVFFSKIHP 2660 V+ + Y +S KEQ+++ ++ E + I E++ + + + ++I Sbjct: 512 KVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRI-- 569 Query: 2661 LQIENKKEFKTADWKTRADPKTFALPKKQQELCVSGTIWSYPNPYTSISPKIIRHKDKAK 2720 L++E+ E + K ++ L ++ + I+ + +HK Sbjct: 570 LELESSLEKSLQENKNQSKDLAVHLEAEKNK------------HNKEITVMVEKHK---- 613 Query: 2721 TADVESTMHTKQIKLKAKRIPVSQLLEYGTASNKKELRGNIQQQKSFQLSKNAVHRVLKA 2780 ++ES H +Q L +++ Q+L+ + ++LR +Q+K L + + +A Sbjct: 614 -TELESLKH-QQDALWTEKL---QVLKQQYQTEMEKLREKCEQEKETLLKDKEI--IFQA 666 Query: 2781 VYDSGYCVSSIKKLTEVKMEKDKPKDRTCILPQPKLEKPLK---EMQRSLSGCTDMSSIL 2837 I+++ E +EK K +L + LK +++ LS D + + Sbjct: 667 ---------HIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKM 717 Query: 2838 RKQEQDIREKEQKH---QSISEDISQYYIGPLRISS---QQINYSSFDAPRIRTDEELEF 2891 KQE + + EQK+ Q + I ++ + R QIN +LE Sbjct: 718 -KQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQIN-------------QLEL 763 Query: 2892 LIAQRAKEKDVGIAKHSVSIPWEREGSKRLDIPLNSKGQNIFFTELDTSQQKICQEQELL 2951 L+ KE+D + +H + KR + L + ++ S Q EQ Sbjct: 764 LL----KERDKHLKEHQAHVENLEADIKRSEGELQQASAKL---DVFQSYQSATHEQTKA 816 Query: 2952 KQEDISMTNLGSMACPIMEPLHLENTGKVTEEEDVYINRKISSHVLGKEGLKETDIFVGS 3011 +E ++ + L + +V ++ + + ++ +++ + Sbjct: 817 YEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSE 876 Query: 3012 KGQKFLCTNSEVQHKVPAEQKEQVNPDHVPESILDSESFL------SKDPLHLKQAVNTA 3065 QK + K+ KEQ + + +++ E+ + K + + +A Sbjct: 877 MEQKVKSLTQVYESKLEDGNKEQ---EQTKQILVEKENMILQMREGQKKEIEILTQKLSA 933 Query: 3066 RKENVTISESFNENLWGKEQSKLDITLKSNRQKMDFSKKLRMKHLSNYYQNKENILESVL 3125 +++++ I E + ++ K++ K ++ + + L+ K L + K+ + Sbjct: 934 KEDSIHILNEEYETKFKNQEKKME---KVKQKAKEMQETLKKKLLDQEAKLKKEL----- 985 Query: 3126 PCILHQLYIENPKKEGSAEEIMSSKVLSPMVEKASHEVGIPVDQPPCSEGIHLNIKGRKE 3185 EN E S +E + + M + S + V R E Sbjct: 986 ---------ENTALELSQKEKQFNAKMLEMAQANSAGISDAVS--------------RLE 1022 Query: 3186 HPQESTHEAFPASVSHSLMDVLQIKSPKVKKALKAINSLGYLTSNTKGIGLLFPRQ---- 3241 Q+ E+ L DV+ I K+ + + + + + K + +Q Sbjct: 1023 TNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILL 1082 Query: 3242 --AEKEE---KYTYKALPKPASHSKTDLFQFNASMQQEKLDAMDIP--------HYDYLT 3288 EKEE + T+ L + T L + ++Q+ + H + L Sbjct: 1083 FGCEKEEMNKEITW--LKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLE 1140 Query: 3289 SQTREAVKQMDVIVGYTQNSKK--RQDLLKTGQKWQYLPISYENFWEHISCPQKYPCLLQ 3346 +++K+ + K +D K + L + E F S +K L+ Sbjct: 1141 VDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLE 1200 Query: 3347 HLMPQEKEALSEGGNLS-----SRTPGLDLFSADQLSTITKNRLEWIVPLISPRQMKKQD 3401 + K+ LSE + +T L ++L I+ ++ I+ IS Q Sbjct: 1201 DKSLEFKK-LSEELAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQ----- 1254 Query: 3402 SMLPLGSYHKTIKYASLLFPKGMKSSD-GVQVFDLISNNSSPKLRLGKKIETQKANEKVQ 3460 H+T K L K S+ Q+ L ++ L + + T + EK Sbjct: 1255 --------HRTTKVKEALLIKTCTVSELEAQLRQLTEEQNT--LNISFQQATHQLEEKEN 1304 Query: 3461 KEVCLPITLHSLSASMPILQESKG-------QKDSVEQVIRKGVICHKRRTSKWKKSVFS 3513 + + + SL LQ+ G +K+S ++K + + + K+ + Sbjct: 1305 QIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKE 1364 Query: 3514 HILNTSDCGASSNRLEMQW----NMTDKMVNVKHRMSEIDLVAAKICESI--LSLPHFKL 3567 + S L +Q ++++K + + D ++ + + LS L Sbjct: 1365 KKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTL 1424 Query: 3568 NKETIDGV---------ISSNVKSTKQHISQGKNDRVKAMDMKRIKSPNIILKPRKSSLS 3618 +KE I + S K + +Q +N + +KS K + +L Sbjct: 1425 SKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLL 1484 Query: 3619 HILSIKEFPLLLDIIKQEGKMQEGKGKSSMKLTNLCTSLPSLS------HSNSNSRTKAG 3672 + + D +K G+M++ K K K +NL T L S + + +T Sbjct: 1485 KE-ELDQQNKRFDCLK--GEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEI 1541 Query: 3673 KDKSGTLKGCLPPLKLQASSNARRVSSAESINRDSLSNVIESKCFPQKKKEDRENIVDVK 3732 + + LK ++ +++ + + + + V KE E I+ ++ Sbjct: 1542 ESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRV----------KEAEEKILTLE 1591 Query: 3733 DIMGLKCITLKGKKSLFRHL-------------LHGKEPQRSNKKLEKMTQEDESNLNVV 3779 + + L+ KK H+ L + S KL ++ ++ E + + Sbjct: 1592 NQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAI 1651 Query: 3780 QNKLCA--------------SILSPPHLEWNPRIKEVYMRGITRFCLSSSTQQEL----- 3820 + +L + S LS + + R +EV++ + SS + L Sbjct: 1652 KKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRS 1711 Query: 3821 -SDTMEKCEQPIDDSLSSIEKAKH----MPQKDKDRVEKALEKIMHSKR--IALEVKQPS 3873 + EQ DS ++K + Q++ EK L+++ K ++ + Sbjct: 1712 AKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRC 1771 Query: 3874 IFQELELNIKEKGGKIQED--------KEVEIWSKPFASISFLPYSKVGTIEGEEAMRIK 3925 +QE + ++ K ED +E+E +K ++ I K G G+ ++ K Sbjct: 1772 QYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEG---GKNNIQAK 1828 Query: 3926 MRSSFSQPNLQE-SSDTEKTAYEKCISDNISNSVKKALESIL----------QKEQRQKM 3974 NL+ D +KT EK ++ I K L+S L +E K Sbjct: 1829 Q-------NLENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKY 1881 Query: 3975 EKIRALKKMKSSISQGIQLDIKEQEKRIEHIKGEPSVLLTNACASIPSPSHLQLDTRREK 4034 EK++AL++M L+ +EK H+ +P LL+N A REK Sbjct: 1882 EKLQALQQMDGRNKPTELLEENTEEKSKSHLV-QPK-LLSNMEAQHNDLEFKLAGAEREK 1939 Query: 4035 AEYVTEITRYY----LPELSHQKSSEAGEKADGVASKGDITIKVQKAKDYMQQKEDDEVK 4090 + EI R + HQ+ E +K ++ + Q++ED E+K Sbjct: 1940 QKLGKEIVRLQKDLRMLRKEHQQELEILKK----------EYDQEREEKIKQEQEDLELK 1989 Query: 4091 -ISAKKDIMHPEDKGLKAKKALSQDLPLNTKEPGKMDQEAQEQGKEDREGE--------- 4140 S K +M + L K+ Q+L + KE QE + + E + E Sbjct: 1990 HNSTLKQLMREFNTQLAQKE---QELEMTIKETINKAQEVEAELLESHQEETNQLLKKIA 2046 Query: 4141 EQGKEDRRGAG--QEKVDREDKEQ----GKMDHEVEEQQKADGVGIEQGKMDGDKNEQER 4194 E+ + +R A +E +D ++E + ++EE QK +EQ + G+ N Sbjct: 2047 EKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNVTIM 2106 Query: 4195 VLFLYLPSNSSLTHYILDTRIEGEEDQQGI 4224 L L ++L I D++++ +E ++ I Sbjct: 2107 ELQTQLAQKTTL---ISDSKLKEQEFREQI 2133 Score = 46.6 bits (109), Expect = 9e-04 Identities = 201/1097 (18%), Positives = 406/1097 (37%), Gaps = 178/1097 (16%) Query: 3522 GASSNRLEMQWNMTDKMVNVKHRMSEIDLVAAKICESILSLPHFKLNKETIDGVISSNVK 3581 G S LE + N+ R E + C + S + +E +D + K Sbjct: 275 GTSVKTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTS--EKEALQEQLDERLQELEK 332 Query: 3582 STKQHISQGKNDRVKAMDMKRI-----KSPNIILKPRKSSLSHILSIKEFPL------LL 3630 H+++ + D K + + +++ K + L +KE + + Sbjct: 333 IKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIK 392 Query: 3631 DIIKQEGKMQEGKGKSSMKLTNLCTSLPSLSHSNSNSRTKAGKDKSGTLKGCLPPLKLQA 3690 + Q +++E K KS S + +R K + +K ++ Sbjct: 393 QMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIK------TIEK 446 Query: 3691 SSNARRVSSAESINRDSLSNVIESKCFPQKKKEDRENIVDVKDIMGLKCITLKGKKSLFR 3750 +S R+S + ++R ++ + KK E I ++ + + L K+ Sbjct: 447 TSEEERISLQQELSR------VKQEVVDVMKKSSEEQIAKLQKLHEKE---LARKEQELT 497 Query: 3751 HLLHGKEPQRSNKKLEKMTQEDESNLNVVQNKLCASILSPPHLEWNPRI----KEVYMRG 3806 L +E + + + + L + Q K L+ LE + E +R Sbjct: 498 KKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRD 557 Query: 3807 ITRFCLSSSTQ-QELSDTMEKCEQPIDDSLSSI------EKAKHMPQ----KDKDRVEKA 3855 + + + T+ EL ++EK Q + + EK KH + +K + E Sbjct: 558 LQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTE-- 615 Query: 3856 LEKIMHSKRIALEVKQPSIFQELELNIKEKGGKIQEDKEVEIWSKPFASISFLPYSKVGT 3915 LE + H + K + Q+ + +++ K +++KE + K + + T Sbjct: 616 LESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKT 675 Query: 3916 IEGEEAMRIKMRSSFSQPNLQESSDTEKTAYEKCISDNISNSVKKALESILQKEQRQKME 3975 +E + + ++ S S+ + + K E + + ++ +K+ LE+ + +++ + Sbjct: 676 LEKLDVKQTELESLSSELS-EVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQ 734 Query: 3976 KI------------RALKKMKSSISQGIQLDIKEQEKRIEHIKGEPSVL----------L 4013 ++ R K +K I+Q ++L +KE++K ++ + L L Sbjct: 735 QVDSIIKEHEVSIQRTEKALKDQINQ-LELLLKERDKHLKEHQAHVENLEADIKRSEGEL 793 Query: 4014 TNACASIPSPSHLQLDTRREKAEYVTEITRYY--LPELSHQKSSEAGEKADGVASKGDIT 4071 A A + Q T + Y ++ + L +L ++ + A+ A K D+ Sbjct: 794 QQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVC 853 Query: 4072 IKVQKAK----DYMQQ--KEDDEVKISAKKDIMHPEDK---GLKAKKALSQ------DLP 4116 ++ K D MQQ K++ E++ K E K G K ++ Q ++ Sbjct: 854 TELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMI 913 Query: 4117 LNTKEPGKMDQEAQEQ---GKEDR----EGEEQGKEDRRGAGQEKVDREDKEQGK----- 4164 L +E K + E Q KED E + K + EKV ++ KE + Sbjct: 914 LQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKK 973 Query: 4165 -MDHEVEEQQKADGVGIEQGKMDGDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQG 4223 +D E + +++ + +E + + K ++L + +++ ++ + +R+E + +Q Sbjct: 974 LLDQEAKLKKELENTALELSQKE--KQFNAKMLEMAQANSAGISDAV--SRLETNQKEQ- 1028 Query: 4224 IIRPGILQPRHQKS-----SETGKKANGVPSEGDSASEVQKAKDYMQQKEED--ESKQET 4276 L H++ S KK N E E+Q +Q+KE++ E KQ+ Sbjct: 1029 ---IESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQ-----LQEKEQEVAELKQKI 1080 Query: 4277 VLFLHLPSESSLTCYELNTRKEGEEDLQGIIKSATLQLRQQKSFDAGKIAHTKSFGVDSS 4336 +LF E E+ KE +G+ + TL Q++ K AH S D + Sbjct: 1081 LLF---GCEKEEMNKEITWLKE-----EGVKQDTTLNELQEQLKQ--KSAHVNSLAQDET 1130 Query: 4337 NDVKTVQEYKPQKEVDRGKTVSVDYIMQPEGTIFEAEQLSLPHTLNIPGSSGSKTREVLT 4396 ++ + + EVD K++ + +Q + + E + L+ K E+ + Sbjct: 1131 K----LKAHLEKLEVDLNKSLKENTFLQEQ--LVELKMLA--------EEDKRKVSELTS 1176 Query: 4397 NIKEKLRHVQERKSELDVFLTIPSLSHCKLDKRTAGKKEEQGVTRSFLPPSWHMESSDTG 4456 +K Q KS SH K +K K S + Sbjct: 1177 KLKTTDEEFQSLKS-----------SHEKSNKSLEDK------------------SLEFK 1207 Query: 4457 KLKYTLSYLNDITGDSN------RTKYMAQIQKDKANISEKSVMHPEYIAVKAEKSPLSH 4510 KL L+ DI +T + I K N + H ++ K +++ L Sbjct: 1208 KLSEELAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALLIK 1267 Query: 4511 ILKTKELQVNISQQGEK 4527 EL+ + Q E+ Sbjct: 1268 TCTVSELEAQLRQLTEE 1284 Score = 36.2 bits (82), Expect = 1.2 Identities = 70/301 (23%), Positives = 124/301 (41%), Gaps = 46/301 (15%) Query: 5671 QNIEEQD-IVMKKQVIRRCEHGHKTRTNTILSKFPLQSGKQKTPS--ETDVDKKTTAHLS 5727 Q I+E D +++++ + R E T L G+ K E + ++K+ +HL Sbjct: 1854 QKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLV 1913 Query: 5728 ----LQMLPGIHMDMTEIDPAKGGRKQALLISE--QEEGVLELLPKSLFPPWTFQFQSGD 5781 L + H D+ E A R++ L E + + L +L K Q + Sbjct: 1914 QPKLLSNMEAQHNDL-EFKLAGAEREKQKLGKEIVRLQKDLRMLRKE------HQQELEI 1966 Query: 5782 LEEKHQTDANTNINLEQKKLEMDNDSTVN-----------QKEGKL----KIGTNRALHL 5826 L++++ + I EQ+ LE+ ++ST+ QKE +L K N+A + Sbjct: 1967 LKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEV 2026 Query: 5827 QEEKTEMHKARTANLEKERGRM--DTSSSAHPHLPSLKAEESQMKTQVITHRENSRLIMQ 5884 + E E H+ T L K+ D +A + L A E +M +V + + + Sbjct: 2027 EAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQK 2086 Query: 5885 K--QKKELEASNAKQSIQLQ----KLFQRNVLDSFYSYVPLSPKCKDQKGRLTIRDLKRE 5938 K QK E E + ++ + +L Q+ L S K K+Q+ R I +L+ Sbjct: 2087 KYQQKLEQEENPGNDNVTIMELQTQLAQKTTLIS-------DSKLKEQEFREQIHNLEDR 2139 Query: 5939 L 5939 L Sbjct: 2140 L 2140 Score = 35.8 bits (81), Expect = 1.5 Identities = 102/487 (20%), Positives = 193/487 (39%), Gaps = 85/487 (17%) Query: 5783 EEKHQTDANTNINLEQKKLEMDNDSTVNQKEGKLKIGTNRALHLQEEKTEMHKARTANLE 5842 ++K A T + + LEM + + Q ++K T + L+E+K + +A LE Sbjct: 360 QDKGMVIAETKRQMHET-LEMKEEE-IAQLRSRIKQMTTQGEELREQKEKSERAAFEELE 417 Query: 5843 KERGRMDTSSSAHPHLPSLKAEESQMKTQVITHRENSRLIMQKQ----KKE----LEASN 5894 K + T+ LKAE + + E R+ +Q++ K+E ++ S+ Sbjct: 418 K---ALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSS 474 Query: 5895 AKQSIQLQKLFQRNVLDSFYSYVPLSPKCKDQKGRLTIRDLKRELSTKYLTMKIQNHPIP 5954 +Q +LQKL ++ L+ K ++ +L R+ + + K K Q+ Sbjct: 475 EEQIAKLQKLHEKE----------LARKEQELTKKLQTREREFQEQMKVALEKSQS---- 520 Query: 5955 QMLNITGRGTPSNRKKLEYDVKLKNIASWSKDVSGIFIRSLSISIMRSPHTDPKTNLERE 6014 + L I S K+ + + L+ + K + L+ S + + R Sbjct: 521 EYLKI------SQEKEQQESLALEELELQKKAI-------LTESENKLRDLQQEAETYRT 567 Query: 6015 KRICLPKFQEKSPNTSEMSKRDTLTIVKGEQNFTN---TVPQDPQPFAVD--KQQMQKLP 6069 + + L EKS ++ +D ++ E+N N TV + ++ K Q L Sbjct: 568 RILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALW 627 Query: 6070 NVKSEANLRSEMNKKYLKAQTKERIVPEHDVSRIIKKPDL----RIIEQEEKILKRI-LT 6124 K + + ++Y K R E + ++K ++ I E EK L+++ + Sbjct: 628 TEKLQV-----LKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVK 682 Query: 6125 PTECPSMLE------------DPKLPKQRDQSEPVWDMTTQKVQQQKAFPGTVPIPPQVK 6172 TE S+ + +L +DQ++ + K+ +QK + +K Sbjct: 683 QTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNH-HQQQVDSIIK 741 Query: 6173 SSEV------KIVADSTNAEHLLPICEATKAISESQ--VKNMIQD--------KVSSDKL 6216 EV K + D N LL + E K + E Q V+N+ D + +S KL Sbjct: 742 EHEVSIQRTEKALKDQINQLELL-LKERDKHLKEHQAHVENLEADIKRSEGELQQASAKL 800 Query: 6217 DNIQAYK 6223 D Q+Y+ Sbjct: 801 DVFQSYQ 807 >gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo sapiens] Length = 1937 Score = 57.0 bits (136), Expect = 6e-07 Identities = 105/622 (16%), Positives = 255/622 (40%), Gaps = 69/622 (11%) Query: 3815 STQQELSDTMEKCEQPIDDSLSSIEKAKHMPQKDKDRVEKALEKIMHSKRIALEVKQ-PS 3873 S L+D E+CEQ I + + K K + ++ ++ E E +++ E + Sbjct: 896 SEADSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKK 955 Query: 3874 IFQELELNI-KEKGGKIQEDKEVEIWSKPFA----SISFLPYSKVGTIEGEEAMRIKMRS 3928 +LEL + K + K + +V+ ++ A +I+ L K E + +++ Sbjct: 956 DIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQA 1015 Query: 3929 SFSQPNLQESSDTEKTAYEKCISDNISNSVKKALESILQKEQRQKMEKIRALKKMKS--S 3986 + N+ + KT E+ + D LE L++E++ +M+ RA +K++ Sbjct: 1016 EEDKVNILTKA---KTKLEQQVDD---------LEGSLEQEKKLRMDLERAKRKLEGDLK 1063 Query: 3987 ISQGIQLDIKEQEKRIEHIKGEPSVLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYL 4046 ++Q +D++ +++++ + ++N + I +++ +++ E I Sbjct: 1064 LAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARI----- 1118 Query: 4047 PELSHQKSSEAGEKADGVASKGDITIKVQKAKDYMQQ---KEDDEVKISAKKDIMHPEDK 4103 EL + +E +A + D++ ++++ + +++ +V+++ K++ Sbjct: 1119 EELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEF---- 1174 Query: 4104 GLKAKKALSQDLPLNTKEPGKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQG 4163 + L +DL E + EA + + + E++D + + Sbjct: 1175 -----QKLRRDL-----EEATLQHEAMVAALRKKHADSMAELG------EQIDNLQRVKQ 1218 Query: 4164 KMDHEVEE-QQKADGVGIEQGKMDGDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQ 4222 K++ E E + + D + + K E++ SL + + + + EE+QQ Sbjct: 1219 KLEKEKSELKMETDDLSSNAEAISKAKGNLEKMC-------RSLEDQVSELKTK-EEEQQ 1270 Query: 4223 GIIRPGILQPRHQKSSETGKKANGVPSEGDSASEVQKAK-------DYMQQKEEDESKQE 4275 +I + R + +E G+ + + + S++ ++K + ++ + E+E+K + Sbjct: 1271 RLIN-DLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAK 1329 Query: 4276 TVLFLHLPS---ESSLTCYELNTRKEGEEDLQGIIKSATLQLRQQKS-FDAGKIAHTKSF 4331 L L S + L + +EG+ +LQ + A ++ Q ++ ++ I T+ Sbjct: 1330 NALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEEL 1389 Query: 4332 GVDSSNDVKTVQEYKPQKEVDRGKTVSVDYIMQPEGTIFEAEQLSLPHTLNIPGSSGSKT 4391 + +QE + E K S++ Q E L + + + K Sbjct: 1390 EEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQ 1449 Query: 4392 REVLTNIKEKLRHVQERKSELD 4413 R + E + +E ++EL+ Sbjct: 1450 RNFDKVLSEWKQKYEETQAELE 1471 Score = 43.9 bits (102), Expect = 0.006 Identities = 108/565 (19%), Positives = 226/565 (40%), Gaps = 91/565 (16%) Query: 3663 SNSNSRTKAGKDKSGTLKGCLPPLKLQASSNARRVSSAESINRDSLSNVIESKCFPQKKK 3722 + S ++ K ++K TL L+LQ S A ++ AE + N I+ + ++ Sbjct: 867 AKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQLEAKIKEVT 926 Query: 3723 EDRENIVDVKDIMGLKCITLKGKKSLFRHLLHGKEPQRSNKKLEKMTQEDE-SNLNVVQN 3781 E E ++ + K L+ + S + + E + + EK E++ NL Sbjct: 927 ERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMA 986 Query: 3782 KLCASILSPPHLEWNPRIKEVYMRGITRFCLSSSTQQELSDTMEKCEQPIDDSLSSIEKA 3841 L +I + ++E + + + L+ K EQ +DD S+E+ Sbjct: 987 GLDETIAKLS--KEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQE 1044 Query: 3842 KHMP------------------------QKDKDRVEKALEK------IMHSK---RIALE 3868 K + + DK ++++ LEK + SK A+E Sbjct: 1045 KKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVE 1104 Query: 3869 VKQPSIFQELELNIKEKGGKIQED---------------KEVEIWSKPFASISFLPYSKV 3913 ++ +EL+ I+E G +I+ + +E+E S+ ++V Sbjct: 1105 IQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQV 1164 Query: 3914 GTIEGEEAMRIKMRSSFSQPNLQESSDTEKTAYEKCISDNISNSVKKALESILQKEQRQK 3973 + EA K+R + LQ + A K +D+++ + + ++++ + +QK Sbjct: 1165 ELNKKREAEFQKLRRDLEEATLQH--EAMVAALRKKHADSMA-ELGEQIDNL--QRVKQK 1219 Query: 3974 MEKIRALKKMKSSISQGIQLDIKEQEKRIEHIKGEPSVLLTNACASIPSPSHLQLDTRRE 4033 +EK ++ KM++ D+ + I KG L C S+ +L T+ E Sbjct: 1220 LEKEKSELKMETD-------DLSSNAEAISKAKGN----LEKMCRSLEDQVS-ELKTKEE 1267 Query: 4034 KAEYVTEITRYYLPELSHQKS---SEAGEKADGVASKGDITIKVQKAKDYMQQKEDDEVK 4090 + + + + +L+ Q++ +EAGE + + K + ++ ++K Q+ + Sbjct: 1268 EQQRL-------INDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIE---- 1316 Query: 4091 ISAKKDIMHPEDKGLKAKKALSQDLPLNTKEPGKMDQEAQEQGKEDREGEEQGKEDRRGA 4150 ++ H ++ KAK AL+ L + + + +EQ +E++EG+ + + A Sbjct: 1317 -----ELKHQLEEETKAKNALAHALQSSRHDCDLL----REQYEEEQEGKAELQRALSKA 1367 Query: 4151 GQEKVDREDKEQGKMDHEVEEQQKA 4175 E K + EE ++A Sbjct: 1368 NSEVAQWRTKYETDAIQRTEELEEA 1392 Score = 39.7 bits (91), Expect = 0.11 Identities = 101/567 (17%), Positives = 224/567 (39%), Gaps = 86/567 (15%) Query: 3756 KEPQRSNKKLEKMTQEDESNLNVVQNKLCASILSPPHLEWNPRIKEVYM---RGITRFCL 3812 +E + + KKL + QE E ++ V K CAS+ N ++++ + R Sbjct: 1387 EELEEAKKKLAQRLQEAEEHVEAVNAK-CASLEKTKQRLQN-EVEDLMLDVERSNAACAA 1444 Query: 3813 SSSTQQELSDTMEKCEQPIDDSLSSIEKAKHMPQ-------KDKDRVEKALEKIMHSKRI 3865 Q+ + + +Q +++ + +E ++ + K K+ E++L+++ +R Sbjct: 1445 LDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRE 1504 Query: 3866 ALEVKQPSIFQELELNIKEKGGKIQE----DKEVEIWSKPFASISFLPYSKVGTIEGEEA 3921 ++Q +L I E G +I E K+VE + I ++E EE Sbjct: 1505 NKNLQQE--ISDLTEQIAEGGKQIHELEKIKKQVE---QEKCEIQAALEEAEASLEHEEG 1559 Query: 3922 MRIKMRSSFSQPNLQESSDTEKTAYEKCISDNISNS---VKKALESILQKEQRQKMEKIR 3978 ++++ +Q +S K A + D + + V + ++S L E R + + +R Sbjct: 1560 KILRIQLELNQV---KSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALR 1616 Query: 3979 ALKKMKSSISQGIQLDIKEQEKRIEHIKGEPSVLLTNA--CASIPSPSHLQLDTRREKAE 4036 KKM+ D+ E E ++ H + L N I + L LD E Sbjct: 1617 VKKKMEG--------DLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQE 1668 Query: 4037 YVTE----------ITRYYLPEL-------------SHQKSSEAGEKADGVASKGDITIK 4073 + E + + + EL + Q+ +A E+ + ++ I Sbjct: 1669 DLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLIN 1728 Query: 4074 VQKA--KDYMQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPLNTKEPG---KMDQE 4128 +K D Q + + E I ++ K + ++++L +M + Sbjct: 1729 TKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN 1788 Query: 4129 AQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADGVGIEQGKMDGD 4188 ++ K+ + ++ ++ G++++ + + +++ EVE +QK + ++ G Sbjct: 1789 LEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVK-----GL 1843 Query: 4189 KNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSSETGKKANGVP 4248 + + RV LT+ + EED++ ++R L + Q ++ K+ Sbjct: 1844 RKHERRV--------KELTY-------QTEEDRKNVLRLQDLVDKLQAKVKSYKR-QAEE 1887 Query: 4249 SEGDSASEVQKAKDYMQQKEEDESKQE 4275 +E S + + K + + EE E + + Sbjct: 1888 AEEQSNANLSKFRKLQHELEEAEERAD 1914 >gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo sapiens] Length = 1935 Score = 55.8 bits (133), Expect = 1e-06 Identities = 184/973 (18%), Positives = 376/973 (38%), Gaps = 151/973 (15%) Query: 3665 SNSRTKAGKDKSGTLKGCLPPLKLQASSNARRVSSAESINRDSLSNVIESKCFPQKKKED 3724 S +R K ++K +L L+LQ + ++ AE + N I+ + ++ E Sbjct: 866 SEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNER 925 Query: 3725 RENIVDVKDIMGLKCITLKGKKSLFRHLLHGKEPQRSNKKLEKMTQEDESNLNVVQNKLC 3784 E+ ++ + K L+ + S + + E + + EK E++ N+ + Sbjct: 926 LEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVK-NLTEEMAG 984 Query: 3785 ASILSPPHLEWNPRIKEVYMRGITRFCLSSSTQQELSDTMEKCEQPIDDSLSSIEKAKHM 3844 + + ++E + + + L+ K EQ +DD S+E+ K + Sbjct: 985 LDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKV 1044 Query: 3845 PQKDKDRVEKALEKIMHSKRIALEVKQPSIFQELELNIKEKGGKIQEDKEVEIWSKPFAS 3904 + D +R ++ LE L++ Q SI +LE N K++ + + K+ E+ Sbjct: 1045 -RMDLERAKRKLEG-------DLKLTQESI-MDLE-NDKQQLDERLKKKDFEL------- 1087 Query: 3905 ISFLPYSKVGTIEGEEAMRIKMRSSFSQ-----PNLQESSDTEKTAYEKCISDNISNSVK 3959 + IE E+A+ +++ + L+E + E+TA Sbjct: 1088 -----NALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTA-------------- 1128 Query: 3960 KALESILQKEQRQKMEKIRALKKMKSSISQGIQLDIKEQEKRIEHIKGEPSVLLTNACAS 4019 R K+EK+R+ + +++E +R+E G SV Sbjct: 1129 -----------RAKVEKLRS----------DLSRELEEISERLEEAGGATSV-------- 1159 Query: 4020 IPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEAGEK--ADGVASKGDITIKVQKA 4077 ++++ +RE AE+ L H+ ++ A K AD VA G+ +Q+ Sbjct: 1160 -----QIEMNKKRE-AEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRV 1213 Query: 4078 KDYMQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPLNTKEPGKMDQEAQEQGKEDR 4137 K + +KE E K+ D+ ++ +KAK L KM + ++Q E R Sbjct: 1214 KQKL-EKEKSEFKLEL-DDVTSNMEQIIKAKANLE-----------KMCRTLEDQMNEHR 1260 Query: 4138 EGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADGVGIEQGKMDGDK--NEQERV 4195 E+ + ++ + E G++ +++E++ + +GK+ + + +R Sbjct: 1261 SKAEETQRSVNDLTSQRA-KLQTENGELSRQLDEKEALIS-QLTRGKLTYTQQLEDLKRQ 1318 Query: 4196 LFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSSETGKKANGVPSEGDSAS 4255 L + + ++L H + R + + +L+ ++++ +E + V S+ +S Sbjct: 1319 LEEEVKAKNALAHALQSARHDCD----------LLREQYEEETEAKAELQRVLSKANSEV 1368 Query: 4256 EVQKAK---DYMQQKEE-DESKQETVLFLHLPSES----SLTCYELNTRKEGEEDLQGII 4307 + K D +Q+ EE +E+K++ L E+ + C L K LQ I Sbjct: 1369 AQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTK---HRLQNEI 1425 Query: 4308 KSATLQLRQQKSFDAGKIAHTKSFGVDSSNDVKTVQEYKPQKEVDRGKTVSVDYIMQPEG 4367 + + + + + A ++F K + E+K + E + + S Q E Sbjct: 1426 EDLMVDVERSNAAAAALDKKQRNFD-------KILAEWKQKYEESQSELES----SQKEA 1474 Query: 4368 TIFEAEQLSLPHTLNIPGSSGSKTREVLTNIKEKLRHVQERKSELDVFLTIPSLSHCKLD 4427 E L + ++ E L K + +++QE S+L L + +L+ Sbjct: 1475 RSLSTELFKLKNAY-------EESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELE 1527 Query: 4428 KRTAGKKEEQGVTRSFLPPSWHMESSDTGKLKYTLSYLNDITGDSNRTKYMAQIQKDKAN 4487 K + E+ +S L + + GK+ N I + R + ++A Sbjct: 1528 KVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAK 1587 Query: 4488 ISEKSVMHPEYIAVKAEKSPLSHILKTK--------ELQVNISQQGEKAQEGEVEIVVL- 4538 + V+ ++ AE + L+ K E+++ +S A E + ++ L Sbjct: 1588 RNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQ 1647 Query: 4539 -LSKTCPFVTSSAFLELDSIKEEEGEPRITRSFMPHLEIQESLPSRQTAPTKPTESLVKK 4597 L K A D +KE R+ + E++E A + TE K Sbjct: 1648 SLLKDTQIQLDDAVRANDDLKENIAIVE-RRNNLLQAELEE-----LRAVVEQTERSRKL 1701 Query: 4598 EKQLLPQKEDRVQ 4610 +Q L + +RVQ Sbjct: 1702 AEQELIETSERVQ 1714 >gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] Length = 1960 Score = 55.5 bits (132), Expect = 2e-06 Identities = 131/661 (19%), Positives = 276/661 (41%), Gaps = 97/661 (14%) Query: 3576 ISSNVKSTKQHISQGKNDRVKAM--------DMKRIKSPNIILKPRKSSLSHILSIKEFP 3627 + N++ ++ + + ++ R K +K+++ IIL+ + L+ KE Sbjct: 941 MQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLA-----KEKK 995 Query: 3628 LLLDIIKQ---EGKMQEGKGKSSMKLTN----LCTSLPSLSHSNSNSRTKAGKDKSGTLK 3680 LL D I + +E K KS KL N + T L R + K + Sbjct: 996 LLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRR---- 1051 Query: 3681 GCLPPLKLQASSNARRVSSAESINRDSLSNVIESKCFPQKKKEDREN-IVDVKDIMGLKC 3739 KL+ S AE + + E K KK+E+ + + V++ K Sbjct: 1052 ------KLEGDSTDLSDQIAEL-----QAQIAELKMQLAKKEEELQAALARVEEEAAQKN 1100 Query: 3740 ITLKGKKSL---FRHLLHGKEPQRSNK-KLEKMTQEDESNLNVVQNKLCASILSPPHLEW 3795 + LK + L L E +R+++ K EK ++ L ++ +L ++ S + Sbjct: 1101 MALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQE 1160 Query: 3796 --NPRIKEVYMRGITRFCLSSSTQQELSDTMEKCEQPIDDSLSSIEKAKHMPQKDKDRVE 3853 + R +EV + T + + + ++ + +K Q +++ +E+ K RV+ Sbjct: 1161 LRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTK--------RVK 1212 Query: 3854 KALEKIMHSKRIALEVKQPSIFQELELNIKEKGGKIQEDKEVEIWSKPFASISFLPYSKV 3913 LEK + LE ++ + E+++ ++ KG + K+VE + + F +V Sbjct: 1213 ANLEKAKQT----LENERGELANEVKVLLQGKGDSEHKRKKVEAQLQEL-QVKFNEGERV 1267 Query: 3914 GTIEGEEAMRIKMRSSFSQPNLQESSDTEKTAYEKCISDNISNSVKKALESILQKEQRQK 3973 T ++ ++++ + L SD++ + K S S + + +LQ+E RQK Sbjct: 1268 RTELADKVTKLQVELD-NVTGLLSQSDSKSSKLTKDFS--ALESQLQDTQELLQEENRQK 1324 Query: 3974 MEKIRALKKMKSSISQGIQLDIKEQEKRIEHIKGEPSVLLTNACASIPSPSHLQLDTRRE 4033 + LK+++ + ++E+E+ +++ + + L H Q+ ++ Sbjct: 1325 LSLSTKLKQVEDE-KNSFREQLEEEEEAKHNLEKQIATL------------HAQVADMKK 1371 Query: 4034 KAEYVTEITRYYLPELSHQKSSEAGEKADGVASKGDITI----KVQKAKDYMQQKEDDEV 4089 K E E + + + + +G++ + + + K++K K +QQ+ DD + Sbjct: 1372 KMEDSVGCL-----ETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLL 1426 Query: 4090 --KISAKKDIMHPEDKGLKAKKALSQDLPLNTKEPGKMDQ-EAQEQGKEDR--------- 4137 ++ + E K K + L+++ ++ K + D+ EA+ + KE + Sbjct: 1427 VDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALE 1486 Query: 4138 EGEEQGKEDRRGAGQEKVDRED-----KEQGKMDHEVEEQQKADGVGIEQGKMDGDKNEQ 4192 E EQ E R Q + + ED + GK HE+E+ ++A +E+ K ++ E Sbjct: 1487 EAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELED 1546 Query: 4193 E 4193 E Sbjct: 1547 E 1547 Score = 37.0 bits (84), Expect = 0.68 Identities = 105/628 (16%), Positives = 240/628 (38%), Gaps = 98/628 (15%) Query: 3919 EEAMRIKMRSSFSQPNLQESSDTEKTAYEKCISDNISNSVKKALESILQKEQRQKMEKIR 3978 EE ++++ + ++ L E +T + +++ + + E+ L E + ++ Sbjct: 852 EELVKVREKQLAAENRLTEM----ETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLT 907 Query: 3979 ALKKMKSSISQGIQLDIKEQEKRIEHIKGEPSVLLTNACASIPSPSHLQLDTRREKAEYV 4038 A K+ I ++ ++E+E+R +H++ E + N Sbjct: 908 AKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQN----------------------- 944 Query: 4039 TEITRYYLPELSHQKSSEAGEKADGVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDIM 4098 + EL Q E + K K++K ++ ED K++ +K ++ Sbjct: 945 -------IQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLL 997 Query: 4099 HPEDK------GLKAKKALSQDLPLNTKEPGKMDQEAQEQGKEDREGEEQGKEDRRGAGQ 4152 ED+ L ++ S+ L + M + +E+ + + + ++ ++ RR Sbjct: 998 --EDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEG 1055 Query: 4153 EKVDREDKEQGKMDHEVEEQQKADGVGIEQGKMDGDKNEQERVLFLYLPSNSSLTHYILD 4212 + D D ++ E Q I + KM K E+E L Sbjct: 1056 DSTDLSD--------QIAELQ----AQIAELKMQLAKKEEELQAAL-------------- 1089 Query: 4213 TRIEGEEDQQGIIRPGILQPRHQKSSETGKKANGVPSEGDSASEVQKAK-DYMQQKEEDE 4271 R+E E Q+ + L+ + S+ + + SE S ++ +K K D ++ E + Sbjct: 1090 ARVEEEAAQKNM----ALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALK 1145 Query: 4272 SKQETVLFLHLPSESSLTCYELNTRKEGE-----EDLQGIIKSATLQLRQQKSFDAGKIA 4326 ++ E L +S+ EL +++E E + L+ K+ Q+++ + + + Sbjct: 1146 TELEDTL------DSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVE 1199 Query: 4327 HTKSFGVDSSNDVKTVQEYKPQKEVDRGKTVS-VDYIMQPEGTIFEAEQLSLPHTLNIPG 4385 + +++ K E +RG+ + V ++Q +G E ++ + L Sbjct: 1200 ELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGD-SEHKRKKVEAQLQELQ 1258 Query: 4386 SSGSKTREVLTNIKEKLRHVQERKSELDVFLTIPSLSHCKLDKRTAGKKEEQGVTRSFLP 4445 ++ V T + +K+ +Q + L+ KL K + + + T+ L Sbjct: 1259 VKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQ 1318 Query: 4446 PSWHMESSDTGKLKYTLSYLNDITGDSNRTKYMAQIQKDKANISEKSV--MHPEYIAVKA 4503 + S + KLK + + N + + +++ + EK + +H + +K Sbjct: 1319 EENRQKLSLSTKLK-------QVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKK 1371 Query: 4504 EKSPLSHILKTKELQVNISQQGEKAQEG 4531 + L+T E + ++ +K EG Sbjct: 1372 KMEDSVGCLETAE---EVKRKLQKDLEG 1396 Score = 33.1 bits (74), Expect = 9.9 Identities = 73/381 (19%), Positives = 154/381 (40%), Gaps = 37/381 (9%) Query: 5781 DLEEKHQTDANTNINLEQKKLEMDNDST-VNQKEGKLKIGTNRALHLQEEKTEMHKARTA 5839 DLEE+ + + LE+ + +++ DST ++ + +L+ +K E +A A Sbjct: 1031 DLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALA 1090 Query: 5840 NLEKERGRMDTSSSAHPHLPSLKAEESQMKTQVITHRENSRLIMQKQKKELEASNAKQSI 5899 +E+E + + A + L+++ S+++ + + R SR +KQK++L + + Sbjct: 1091 RVEEEAAQ---KNMALKKIRELESQISELQEDLESERA-SRNKAEKQKRDL-----GEEL 1141 Query: 5900 QLQKLFQRNVLDSFYSYVPLSPKCKDQKGRLTIRDLKRELSTKYLTMKIQNHPIPQMLNI 5959 + K + LDS + L K + + + LK+ L + T + Q I +M Sbjct: 1142 EALKTELEDTLDSTAAQQELRSKREQE-----VNILKKTLEEEAKTHEAQ---IQEMRQK 1193 Query: 5960 TGRGTPSNRKKLEYDVKLKNIASWSKDV----SGIFIRSLSISIMRSPHTDPK-TNLERE 6014 + ++LE ++K +K G + + + ++ K +E + Sbjct: 1194 HSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQ 1253 Query: 6015 KRICLPKFQEKSPNTSEMSKRDTLTIVKGEQNFTNTVPQ-DPQPFAVDKQQMQKLPNVKS 6073 + KF E +E++ + T V+ + N T + Q D + + K ++ Sbjct: 1254 LQELQVKFNEGERVRTELADKVTKLQVELD-NVTGLLSQSDSKSSKLTKDFSALESQLQD 1312 Query: 6074 EANLRSEMNKKYLKAQTK------------ERIVPEHDVSRIIKKPDLRIIEQEEKILKR 6121 L E N++ L TK E++ E + ++K + Q + K+ Sbjct: 1313 TQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKK 1372 Query: 6122 ILTPTECPSMLEDPKLPKQRD 6142 + C E+ K Q+D Sbjct: 1373 MEDSVGCLETAEEVKRKLQKD 1393 >gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 750 Score = 54.7 bits (130), Expect = 3e-06 Identities = 93/482 (19%), Positives = 203/482 (42%), Gaps = 61/482 (12%) Query: 3719 QKKKEDR--ENIVDVKDIMGLKCITLKGKKSLFRHLLHGKEPQRSNKKLEKMTQEDES-- 3774 QKKK DR E + +D + L+ L+R+ + +E + N KL++ Q ES Sbjct: 187 QKKKADRYIEELTKERDALSLE---------LYRNTITDEELKEKNAKLQEKLQLVESEK 237 Query: 3775 -----NLNVVQNKLCASILSPPHLEWNPR----------IKEVYMRGITRFCLSSSTQQE 3819 N+ ++ KL + L P + + + L + Q+ Sbjct: 238 SEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQ 297 Query: 3820 LSDTMEKCEQPIDDSLSSIEKAKHMPQKDKDRVEKALEKIMHSKRIALEVKQPSIFQELE 3879 + M + E+ I + I++ + ++ ++++ + EK+ + + E ++ QE Sbjct: 298 QEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEM 357 Query: 3880 LNIKEKGGKIQEDKEVEIWSKPFASISFLPYSKVGTIEGEEAMRIKMRSSFSQPNLQESS 3939 + KE+ + QE+ +W K + + E EE +R Q ++E Sbjct: 358 MWEKEEKMRRQEEM---MWEKE----EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQE 410 Query: 3940 DTEKTAYEKCISDNISNSVKKALESILQKEQRQKMEKIRALKKMKSSISQGI--QLDIKE 3997 EK E+ I + ++A +++ R++ EKIR +K + I Q I+E Sbjct: 411 --EKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIRE 468 Query: 3998 QEKRIEHIKGEPSVLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEA 4057 +EKR E Q + E+ E + + + E +K E Sbjct: 469 EEKRQEQ-----------------EEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEK 511 Query: 4058 GEKADGVASKGDITIKVQKAKDYMQ-QKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLP 4116 + + + + I+ Q+ K + Q +K ++ ++ +++ MH ++K + +K Q+ Sbjct: 512 VWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDK 571 Query: 4117 LNTKEPGKMDQE----AQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQ 4172 + +E +QE QE+ ++E + Q +E++ +EK+ ++++ + + ++ EQ Sbjct: 572 MWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQ 631 Query: 4173 QK 4174 ++ Sbjct: 632 EE 633 Score = 38.1 bits (87), Expect = 0.31 Identities = 65/364 (17%), Positives = 166/364 (45%), Gaps = 30/364 (8%) Query: 3832 DDSLSSIEKAKHMPQKDKDRVEKALEKIMHSKRIALEVKQPSIFQELELNIKEKGGKIQE 3891 ++ + +E+ H +K +++ EK E+ ++ + ++ ++++ E I+E+ KI+E Sbjct: 390 EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEE-KIREQEEKIRE 448 Query: 3892 DKEVEIWSKPFASISFLPYSKVGTIEG--EEAMRIKMRSSFSQPNLQESSDTEKTAYEKC 3949 +E ++W + K+ E EE R + + Q ++ + E+ +K Sbjct: 449 -QEKKMWRQE---------EKIHEQEKIREEEKRQEQEEMWRQE--EKIHEQEEIWRQKE 496 Query: 3950 ISDNISNSVKKALESILQKEQ--RQKMEKIRALKKMKSSISQGIQLDIKEQEKRIEHIKG 4007 ++K E + ++E+ R++ EKIR ++ + I+ + +E + E + Sbjct: 497 KMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIR-EQEEMWREEEKMHE 555 Query: 4008 EPSVLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEAGEKADGVASK 4067 + + Q + RE+ E V + E ++ E ++ + K Sbjct: 556 QEKIWEEEKRQEQEDKMWRQEEKIREQEEKV------WRQEEKIREQEEKRQEQEEKMWK 609 Query: 4068 GDITIKVQKAKDYMQQKE--DDEVKISAKKDIMHPEDK--GLKAKKALSQDLPLNTKEPG 4123 + I+ Q+ K Q+++ + E KI ++++ +++ G + +K Q+ + +E Sbjct: 610 QEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEET 669 Query: 4124 --KMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADGVGIE 4181 + +++ +EQ K+ RE EE+ +E +++ ++E+ + E + Q++ + + + Sbjct: 670 MWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQ 729 Query: 4182 QGKM 4185 + KM Sbjct: 730 EEKM 733 Score = 34.3 bits (77), Expect = 4.4 Identities = 64/383 (16%), Positives = 168/383 (43%), Gaps = 44/383 (11%) Query: 3817 QQELSDTMEKCEQPIDDSLSSIEKAKHMPQKDKDRVEKALEKIMHSKRIALEVKQPSIFQ 3876 Q+E+ E+ + +++ + EK + +K ++ EK E+ ++ A +Q + Sbjct: 382 QEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEE-EKIREQEKRQEQEAKMWRQEEKIR 440 Query: 3877 ELELNIKEKGGKI--------QEDKEVEIWSKPFASISFLPYSKVGTIEGEEAMRIKMRS 3928 E E I+E+ K+ +++K E + + K+ E EE R K + Sbjct: 441 EQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIH--EQEEIWRQKEKM 498 Query: 3929 SFSQPNLQESSDTEKTAYEKCISDNISNSVKKALESILQKEQR--QKMEKIRALKKM--- 3983 + +++ + EK +++ E I ++E++ ++ EKIR ++M Sbjct: 499 HEQEEKIRKQEEKVWRQEEK---------IREQEEKIREQEEKMWRQEEKIREQEEMWRE 549 Query: 3984 --KSSISQGIQLDIKEQEKRIEHIKGEPSVLLTNACASIPSPSHLQLDTRREKAEYVTEI 4041 K + I + K QE+ + + E + + + +R++ E Sbjct: 550 EEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEE---- 605 Query: 4042 TRYYLPELSHQKSSEAGEKADGVASKGDITIKVQKAKDYMQQKED----DEVKISAKKDI 4097 + E ++ + E+ + + + + K+++ ++ Q++E+ E K+ +++ Sbjct: 606 KMWKQEEKIREQEEKIQEQEEKIREQEE---KIREQEEMTQEQEEKMGEQEEKMCEQEEK 662 Query: 4098 MHPEDKGL--KAKKALSQDLPLNTKEPGKMDQEAQEQGKEDREGEEQGK----EDRRGAG 4151 M +++ + + +K Q+ + +E +QE Q +E++ E++ K E++ Sbjct: 663 MQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQ 722 Query: 4152 QEKVDREDKEQGKMDHEVEEQQK 4174 +EK+ R++++ + + + +Q++ Sbjct: 723 EEKMRRQEEKMWEQEVRLRQQEE 745 Score = 33.5 bits (75), Expect = 7.6 Identities = 35/201 (17%), Positives = 87/201 (43%), Gaps = 10/201 (4%) Query: 2791 IKKLTEVKMEKDKPKDRTCILPQPKLEKPLKEMQRSLSGCTDMSSILRKQEQDIREKEQK 2850 I++ E+ E++K ++ I + K ++ +M R + + +QE+ IRE+E+K Sbjct: 540 IREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEK 599 Query: 2851 HQSISEDISQYYIGPLRISSQQINYSS----FDAPRIRTDEELEFLIAQRAKEKDVGIAK 2906 Q E + + +R ++I +IR EE+ ++ E++ + + Sbjct: 600 RQEQEEKMWKQE-EKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCE 658 Query: 2907 HSVSIPWEREGSKRLDIPLNSKGQNIFFTELDTSQQKICQEQELLKQEDISMTNLGSMAC 2966 + + E R + + + + I ++KI +++E++++++ M C Sbjct: 659 QEEKMQEQEETMWRQEEKIREQEKKI-----REQEEKIREQEEMMQEQEEKMWEQEEKMC 713 Query: 2967 PIMEPLHLENTGKVTEEEDVY 2987 E + + +EE ++ Sbjct: 714 EQEEKMQEQEEKMRRQEEKMW 734 >gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 [Homo sapiens] Length = 916 Score = 54.7 bits (130), Expect = 3e-06 Identities = 87/443 (19%), Positives = 180/443 (40%), Gaps = 52/443 (11%) Query: 3785 ASILSPPHLEWNPRIKEVYMRGITRFCLSSSTQQELSDTMEKCEQPIDDSLSSIEKAKHM 3844 +S + P +E P++K V + + + + E S+ E ++ S+++ K Sbjct: 433 SSKIQKPKVE-APKLK-VQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKE 490 Query: 3845 PQKDKDRVEKALEKIMHSKRIALEVKQPSIFQELELNIKEKGGKIQEDKEVEIWSKPFAS 3904 ++K+ +A E+ + +K+ ++ P + +E E +E+ G+ +E++E E Sbjct: 491 AAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEE-EGEKEEEEGQEEEEEEDE-------- 541 Query: 3905 ISFLPYSKVGTIEGEEAMRIKMRSSFSQPNLQESSDTEKTAYEKCISDNISNSVKKALES 3964 + + EE K SS + QE +TE A + V++ E Sbjct: 542 -------GAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEE 594 Query: 3965 ILQKEQRQKMEKIRALKKMKSSISQGIQLDIKEQEKR------IEHIKGEP---SVLLTN 4015 + KE+ K+ +K KS + + ++E+ K +E P S + Sbjct: 595 VATKEELVADAKVEKPEKAKSPVPKS---PVEEKGKSPVPKSPVEEKGKSPVPKSPVEEK 651 Query: 4016 ACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEAGEKADGVASKGDIT-IKV 4074 + +P + V E + +P+ +++ E G + + +K Sbjct: 652 GKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKE 711 Query: 4075 QKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAK-----KALSQDLPLNTKEPGK---MD 4126 ++ +++KE+ + KK P + A+ K++ L TKE GK + Sbjct: 712 APKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQE 771 Query: 4127 QEAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADGVGIEQG--- 4183 +E ++ G E EE + +G+ +E + + +GK + E E ++K G E+G Sbjct: 772 KEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEKGVVT 831 Query: 4184 ----------KMDGDKNEQERVL 4196 K GDK+E++ V+ Sbjct: 832 NGLDLSPADEKKGGDKSEEKVVV 854 Score = 50.4 bits (119), Expect = 6e-05 Identities = 134/746 (17%), Positives = 309/746 (41%), Gaps = 111/746 (14%) Query: 3815 STQQELSDTMEKCEQPIDDSLSSIEKAKHMPQKDKDRVEKALEKIMHSKRIALEVKQPSI 3874 S Q E++ E+ + D L+ I+ A H+ + KD ++ + + R LE Sbjct: 226 SLQDEVAFLRSNHEEEVADLLAQIQ-ASHITVERKDYLKTDISTALKEIRSQLESHSDQN 284 Query: 3875 FQELELNIKEKGGKIQEDKEVEIWSKPFASISFLPYSKVGTIEGEEAMRIKMRSSFSQPN 3934 + E K + K+ E E + + +K E ++ K S Sbjct: 285 MHQAEEWFKCRYAKLTEAAE--------QNKEAIRSAKEEIAEYRRQLQSKSIELESVRG 336 Query: 3935 LQESSDTEKTAYEKCISDNISNSVKKALESILQKEQRQKMEKIRALKKMKSSISQGIQLD 3994 +ES + + + E+ + ++S S + ++ + + + K E R L++ + ++ + LD Sbjct: 337 TKESLERQLSDIEERHNHDLS-SYQDTIQQLENELRGTKWEMARHLREYQDLLNVKMALD 395 Query: 3995 IKEQEKRIEHIKGEPSVLLTNACASIPSPSH-----LQLDTRREKAEYVT---EITRYYL 4046 I+ R + ++GE + T A SI P + + + ++ +K + ++ ++ Sbjct: 396 IEIAAYR-KLLEGEETRFSTFA-GSITGPLYTHRPPITISSKIQKPKVEAPKLKVQHKFV 453 Query: 4047 PELSHQ-----KSSEAGEKADGVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDIMHPE 4101 E+ + + SE E + + +++K +K + +++E+ E E Sbjct: 454 EEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEA-----------E 502 Query: 4102 DKGLKAKKALSQDLPLNTKEPGKMDQEAQEQGKEDREGEEQGKEDRRGA--------GQE 4153 ++ + AKK+ P+ P ++E + KE+ EG+E+ +E+ GA G E Sbjct: 503 EEEVAAKKS-----PVKATAPEVKEEEGE---KEEEEGQEEEEEEDEGAKSDQAEEGGSE 554 Query: 4154 KVDREDKEQGKMDHEVEEQQKADGVGIEQGKMDGDKNEQERVLFLYLPSNSSLTHYILDT 4213 K +KE+G+ + E E + +A+G E+ + +K +E+ ++ + D Sbjct: 555 KEGSSEKEEGEQE-EGETEAEAEG---EEAEAKEEKKVEEK-----SEEVATKEELVADA 605 Query: 4214 RIEGEEDQQGIIRPGILQPRHQ----KSSETGKKANGVPS---EGDSASEV------QKA 4260 ++E E + + ++ + + KS K + VP E S V +K Sbjct: 606 KVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKG 665 Query: 4261 KDYMQQKEEDESKQETVLFLHLPSESSLTCYEL---NTRKEGEEDLQGIIKSATLQLRQQ 4317 K + + +E + V P E + + E+ ++E E++++ K ++ +++ Sbjct: 666 KSPVSKSPVEEKAKSPV--PKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEE 723 Query: 4318 KSFDAGKIAHTKSFGVDSS-----NDVKTVQEYKPQKEVDRGKTVSVDYIMQPEGTIFEA 4372 K D + +S + + K+V+ + ++ + GK + + + G + Sbjct: 724 KPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGS 783 Query: 4373 EQLSLPHTLNIPGSSGSKTREVLTNIKEKLRHVQERKSELDVFLTIPSLSHCKLDKRTAG 4432 E+ + G+ GS+ ++ N + + + E++++ ++ +G Sbjct: 784 EEEG-----SDKGAKGSRKEDIAVNGEVEGKEEVEQETK----------------EKGSG 822 Query: 4433 KKEEQGVTRS--FLPPSWHMESSDTGKLKYTLS-YLNDIT--GDSNRTKYMAQIQKDKAN 4487 ++EE+GV + L P+ + D + K ++ + IT G TKY+ + Sbjct: 823 REEEKGVVTNGLDLSPADEKKGGDKSEEKVVVTKTVEKITSEGGDGATKYITKSVTVTQK 882 Query: 4488 ISE-KSVMHPEYIAVKAEKSPLSHIL 4512 + E + + ++ K + SH + Sbjct: 883 VEEHEETFEEKLVSTKKVEKVTSHAI 908 Score = 40.4 bits (93), Expect = 0.062 Identities = 93/569 (16%), Positives = 225/569 (39%), Gaps = 99/569 (17%) Query: 3752 LLHGKEPQRSNKKLEKMTQEDESNLNVVQNKLCASILSPPHLEWNPRIKEVYMRGITRFC 3811 LL+G + KL + ++++ L + ++ I +LE + E ++ + + Sbjct: 83 LLNGGSGPGGDYKLSRSNEKEQ--LQGLNDRFAGYIEKVHYLEQQNKEIEAEIQALRQ-- 138 Query: 3812 LSSSTQQELSDTMEKCEQPIDDSLSSIEKAKHMPQKDKDRVEKALEKIMH--SKRIALEV 3869 ++ +L D ++ + + +L + K Q D D +E+ + ++ + L Sbjct: 139 -KQASHAQLGDAYDQEIRELRATLEMVNHEKAQVQLDSDHLEEDIHRLKERFEEEARLRD 197 Query: 3870 KQPSIFQELELNIKEKG-GKIQEDKEVEIWSKPFASISFLPYSKVG-----------TIE 3917 + + L +I+E K++ DK+V+ A + +V T+E Sbjct: 198 DTEAAIRALRKDIEEASLVKVELDKKVQSLQDEVAFLRSNHEEEVADLLAQIQASHITVE 257 Query: 3918 GEEAMRIKMRSSFSQPNLQESSDTEKTAYE-----KCISDNISNSVKKALESILQKEQRQ 3972 ++ ++ + ++ + Q S +++ ++ KC ++ + ++ E+I + ++ Sbjct: 258 RKDYLKTDISTALKEIRSQLESHSDQNMHQAEEWFKCRYAKLTEAAEQNKEAI--RSAKE 315 Query: 3973 KMEKIRALKKMKSSISQGIQLDIKEQEKRIEHIKGEPSVLLTNACASIPSPSHLQLDTRR 4032 ++ + R + KS + ++ + E+++ I+ + L++ +I + T+ Sbjct: 316 EIAEYRRQLQSKSIELESVRGTKESLERQLSDIEERHNHDLSSYQDTIQQLENELRGTKW 375 Query: 4033 EKAEYVTE------ITRYYLPELSHQKSSEAGEKADGVASKGDIT--------------- 4071 E A ++ E + E++ + GE+ G IT Sbjct: 376 EMARHLREYQDLLNVKMALDIEIAAYRKLLEGEETRFSTFAGSITGPLYTHRPPITISSK 435 Query: 4072 ---IKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPLNTKEPGKMDQE 4128 KV+ K +Q K +E+ K + E + +A A++++L ++ KE K E Sbjct: 436 IQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEME--EALTAITEELAVSMKEEKKEAAE 493 Query: 4129 AQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADGVGIEQGKMDGD 4188 +E+ E E E K+ A +V E+ E+ + + + EE+++ +G +Q + Sbjct: 494 EKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAE---- 549 Query: 4189 KNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSSETGKKANGVP 4248 EG +++G + +K G Sbjct: 550 ---------------------------EGGSEKEG----------------SSEKEEGEQ 566 Query: 4249 SEGDSASEVQKAKDYMQQKEEDESKQETV 4277 EG++ +E + + +++++ E K E V Sbjct: 567 EEGETEAEAEGEEAEAKEEKKVEEKSEEV 595 Score = 38.1 bits (87), Expect = 0.31 Identities = 103/543 (18%), Positives = 217/543 (39%), Gaps = 82/543 (15%) Query: 2640 AKINVAEEFNPESVFFSKIHPLQIENKKEFKTADWKTRADPKTFALPKKQQELCVSGTIW 2699 AK+ A E N E++ +K + + + K+ + ++ K + E +S Sbjct: 297 AKLTEAAEQNKEAIRSAKEEIAEYRRQLQSKSIELESVRGTK------ESLERQLSDIEE 350 Query: 2700 SYPNPYTSISPKIIRHKDKAKTADVESTMHTKQIKLKAKRIPVSQLLEYGTASNKKELRG 2759 + + +S I + +++ + E H ++ + + V L+ A+ +K L G Sbjct: 351 RHNHDLSSYQDTIQQLENELRGTKWEMARHLREYQ---DLLNVKMALDIEIAAYRKLLEG 407 Query: 2760 NIQQQKSFQLSKNAVHRVLKAVYDSGYCVSSIKKLTEVKMEKDKPKDRTC----ILPQPK 2815 + +F S + +Y ++ K+ + K+E K K + I+ + K Sbjct: 408 EETRFSTFAGS------ITGPLYTHRPPITISSKIQKPKVEAPKLKVQHKFVEEIIEETK 461 Query: 2816 LEKPLKEMQRSLSGCTDMSSILRKQE--QDIREKEQKHQSISEDISQYYIGPLRISSQQI 2873 +E EM+ +L+ T+ ++ K+E + EKE++ ++ E+++ P++ ++ ++ Sbjct: 462 VEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKK-SPVKATAPEV 520 Query: 2874 NYSSFDAPRIRTDEELEFLIAQRAKEKDVGIAKHSVSIPWEREGSKRLDIPLNSKGQNIF 2933 + EE E E+D G E GS++ +G+ Sbjct: 521 KEEEGEKEEEEGQEEEE--------EEDEGAKSDQA----EEGGSEKEGSSEKEEGEQ-- 566 Query: 2934 FTELDTSQQKICQEQELLKQEDISMTNLGSMACPIMEPLHLENTGKVTEEEDVYINRKIS 2993 E +T + +E E +++ + E + +V +E++ + K+ Sbjct: 567 -EEGETEAEAEGEEAEAKEEKKVE-----------------EKSEEVATKEELVADAKVE 608 Query: 2994 SHVLGKEGLKETDIFVGSKGQKFLCTNSEVQHK----VPAEQKEQVNPDHVPESILD--S 3047 K + ++ V KG K S V+ K VP E+ VP+S ++ Sbjct: 609 KPEKAKSPVPKSP--VEEKG-KSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKG 665 Query: 3048 ESFLSKDPLHLKQAVNTARKENVTISESFNENLWGKEQSKLDITLKSNRQKMDFSKKLRM 3107 +S +SK P+ ++A + K V E++K + QK + K+++ Sbjct: 666 KSPVSKSPVE-EKAKSPVPKSPV-------------EEAKSKAEVGKGEQKEEEEKEVKE 711 Query: 3108 KHLSNYYQNKENILESVLPCILHQLYIENP-KKEGSAEEIMSSKVLSPMVEKASHEVGIP 3166 + KE + V + E+P K+E AE + +K + +EK + E G P Sbjct: 712 APKEEKVEKKEEKPKDV----PEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKP 767 Query: 3167 VDQ 3169 + Q Sbjct: 768 LQQ 770 >gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 [Homo sapiens] Length = 540 Score = 54.7 bits (130), Expect = 3e-06 Identities = 87/443 (19%), Positives = 180/443 (40%), Gaps = 52/443 (11%) Query: 3785 ASILSPPHLEWNPRIKEVYMRGITRFCLSSSTQQELSDTMEKCEQPIDDSLSSIEKAKHM 3844 +S + P +E P++K V + + + + E S+ E ++ S+++ K Sbjct: 57 SSKIQKPKVE-APKLK-VQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKE 114 Query: 3845 PQKDKDRVEKALEKIMHSKRIALEVKQPSIFQELELNIKEKGGKIQEDKEVEIWSKPFAS 3904 ++K+ +A E+ + +K+ ++ P + +E E +E+ G+ +E++E E Sbjct: 115 AAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEE-EGEKEEEEGQEEEEEEDE-------- 165 Query: 3905 ISFLPYSKVGTIEGEEAMRIKMRSSFSQPNLQESSDTEKTAYEKCISDNISNSVKKALES 3964 + + EE K SS + QE +TE A + V++ E Sbjct: 166 -------GAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEE 218 Query: 3965 ILQKEQRQKMEKIRALKKMKSSISQGIQLDIKEQEKR------IEHIKGEP---SVLLTN 4015 + KE+ K+ +K KS + + ++E+ K +E P S + Sbjct: 219 VATKEELVADAKVEKPEKAKSPVPKS---PVEEKGKSPVPKSPVEEKGKSPVPKSPVEEK 275 Query: 4016 ACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEAGEKADGVASKGDIT-IKV 4074 + +P + V E + +P+ +++ E G + + +K Sbjct: 276 GKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKE 335 Query: 4075 QKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAK-----KALSQDLPLNTKEPGK---MD 4126 ++ +++KE+ + KK P + A+ K++ L TKE GK + Sbjct: 336 APKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQE 395 Query: 4127 QEAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADGVGIEQG--- 4183 +E ++ G E EE + +G+ +E + + +GK + E E ++K G E+G Sbjct: 396 KEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEKGVVT 455 Query: 4184 ----------KMDGDKNEQERVL 4196 K GDK+E++ V+ Sbjct: 456 NGLDLSPADEKKGGDKSEEKVVV 478 Score = 37.7 bits (86), Expect = 0.40 Identities = 88/441 (19%), Positives = 177/441 (40%), Gaps = 73/441 (16%) Query: 2742 VSQLLEYGTASNKKELRGNIQQQKSFQLSKNAVHRVLKAVYDSGYCVSSIKKLTEVKMEK 2801 V L+ A+ +K L G + +F S + +Y ++ K+ + K+E Sbjct: 14 VKMALDIEIAAYRKLLEGEETRFSTFAGS------ITGPLYTHRPPITISSKIQKPKVEA 67 Query: 2802 DKPKDRTC----ILPQPKLEKPLKEMQRSLSGCTDMSSILRKQE--QDIREKEQKHQSIS 2855 K K + I+ + K+E EM+ +L+ T+ ++ K+E + EKE++ ++ Sbjct: 68 PKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEE 127 Query: 2856 EDISQYYIGPLRISSQQINYSSFDAPRIRTDEELEFLIAQRAKEKDVGIAKHSVSIPWER 2915 E+++ P++ ++ ++ + EE E E+D G E Sbjct: 128 EEVAAKK-SPVKATAPEVKEEEGEKEEEEGQEEEE--------EEDEGAKSDQA----EE 174 Query: 2916 EGSKRLDIPLNSKGQNIFFTELDTSQQKICQEQELLKQEDISMTNLGSMACPIMEPLHLE 2975 GS++ +G+ E +T + +E E +++ + E Sbjct: 175 GGSEKEGSSEKEEGEQ---EEGETEAEAEGEEAEAKEEKKVE-----------------E 214 Query: 2976 NTGKVTEEEDVYINRKISSHVLGKEGLKETDIFVGSKGQKFLCTNSEVQHK----VPAEQ 3031 + +V +E++ + K+ K + ++ V KG K S V+ K VP Sbjct: 215 KSEEVATKEELVADAKVEKPEKAKSPVPKSP--VEEKG-KSPVPKSPVEEKGKSPVPKSP 271 Query: 3032 KEQVNPDHVPESILD--SESFLSKDPLHLKQAVNTARKENVTISESFNENLWGKEQSKLD 3089 E+ VP+S ++ +S +SK P+ ++A + K V E++K Sbjct: 272 VEEKGKSPVPKSPVEEKGKSPVSKSPVE-EKAKSPVPKSPV-------------EEAKSK 317 Query: 3090 ITLKSNRQKMDFSKKLRMKHLSNYYQNKENILESVLPCILHQLYIENP-KKEGSAEEIMS 3148 + QK + K+++ + KE + V + E+P K+E AE + Sbjct: 318 AEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDV----PEKKKAESPVKEEAVAEVVTI 373 Query: 3149 SKVLSPMVEKASHEVGIPVDQ 3169 +K + +EK + E G P+ Q Sbjct: 374 TKSVKVHLEKETKEEGKPLQQ 394 >gi|221219020 NYD-SP11 protein [Homo sapiens] Length = 2873 Score = 54.3 bits (129), Expect = 4e-06 Identities = 90/434 (20%), Positives = 188/434 (43%), Gaps = 68/434 (15%) Query: 3817 QQELSDTMEKCEQPIDDSLSSIEKAKHMPQKDKDRVEKALEKIMHSKRIALEVKQPSIFQ 3876 +++L++T +K Q ++DSL+ ++ K +K K +EKA+ + R L++ + Sbjct: 1906 KEKLAETEKKLVQ-VEDSLAK-KQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKAL 1963 Query: 3877 ELELN-IKEKGGKIQEDKEV--------------------EIWSKPFASIS--FLPYSKV 3913 LE+ + E+ ++ E KE E++ + + L ++ Sbjct: 1964 NLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKILLHEDRI 2023 Query: 3914 GTIEGEEAMRIKMRSSFSQPNLQESSDTEKTAYEKCISDNIS--------NSVKKALESI 3965 +E E + K+ + Q + A K I S N + KAL+ + Sbjct: 2024 LAMEESEIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLNKILKALQKL 2083 Query: 3966 LQKEQRQKMEKIRA--------LKKMKSSISQGIQLDIKE---QEKRIEHIKGEPSVLLT 4014 + E++ E+I+ +K+ + SI Q +LDIKE EKR E K E L Sbjct: 2084 TRDERKLTQEEIKMTKMKRALFVKERRLSIEQS-KLDIKEWDFSEKRSELTKDEKK--LA 2140 Query: 4015 NACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEAGEKADGVASKGDITIKV 4074 + + ++ + E +++ R H + E+ G+ + I Sbjct: 2141 RKQRKLANKMRRMINKEEKMTEEESKLAR------KHSEVILDDEEEGGIEEEEVIPFLK 2194 Query: 4075 QKAKDYMQQKEDDEVK--ISAKKDIMHPEDKGLKAKKALSQDLP----LNTKEPGKMDQE 4128 ++ + + K D+ K S++ D + E+ + ++L +L L+++E + ++E Sbjct: 2195 RRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEE 2254 Query: 4129 AQEQGKEDREGEEQGKEDRRG----AGQEKVDREDKEQGKMDHEVEE-----QQKADGVG 4179 + + +E RE EE+ KE+ G +E+ +++ K++ K EV+E ++K + + Sbjct: 2255 EEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMS 2314 Query: 4180 IEQGKMDGDKNEQE 4193 E+ + D+ E+E Sbjct: 2315 EEETESLSDEEEEE 2328 Score = 45.1 bits (105), Expect = 0.003 Identities = 124/666 (18%), Positives = 260/666 (39%), Gaps = 98/666 (14%) Query: 3710 NVIESKCFPQKKK--EDRENIVDVKDIMGLKCITLKGKKSLFRHLLHGKEPQRSNKKLEK 3767 N E K +KKK E+ E + ++ + + L ++ L L+ KE +K EK Sbjct: 1736 NQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEEL---LIQEKEKLAQHK--EK 1790 Query: 3768 MTQEDE----SNLNVVQNKLCASILSPPHLEWNPRIKEVYMRGITRFCLSSSTQQE--LS 3821 M +E+E +++ K+ L+ W ++E+ + + + Q++ L+ Sbjct: 1791 MPEEEERLGRKREQLIEKKMK---LAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLA 1847 Query: 3822 DTMEKCEQPIDDSLSSIEKAKHMPQK------------------------DKDRVEKALE 3857 EK Q ++ L + E+ H ++ +K+ V K E Sbjct: 1848 QEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKE 1907 Query: 3858 KIMHSKRIALEVKQPSIFQELELNIKEKGGKIQEDKEVEIWSKPFASISFLPYSKVGTIE 3917 K+ +++ ++V+ S+ ++ E +EK E V+ + + K +E Sbjct: 1908 KLAETEKKLVQVED-SLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKALNLE 1966 Query: 3918 GEEAMRIKMRSSFSQPNLQESSDTEKTAYEKCISDNISNSVKKALESILQKEQRQKMEKI 3977 + KMR + L + E + K ++ ++ E L E++ + + Sbjct: 1967 MKRLAEEKMRLVEGKETLSKGETPETSRQRK-----MTQVEQELFERKLSLEEKILLHED 2021 Query: 3978 RALKKMKSSISQGIQLDIKEQEKRIEHIKGEPSVLLTNACASIPSPSHLQLDTRREKAEY 4037 R L +S I++G ++E +G+ + + S + R ++ Sbjct: 2022 RILAMEESEIAKG----------KLEFTRGQR--IFVQGQRKLAKASRKLIKKRESLSKE 2069 Query: 4038 VTEITRYY--LPELSHQKSSEAGEKADGVASKGDITIKVQKAKDYMQQKEDDEVKISAKK 4095 ++ + L +L+ + E+ K + +K ++ + + E S K+ Sbjct: 2070 PAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKR 2129 Query: 4096 DIMHPEDKGLKAK-KALSQDLPLNTKEPGKMDQEAQEQGKEDRE-----GEEQGKED--- 4146 + ++K L K + L+ + + KM +E + ++ E EE G E+ Sbjct: 2130 SELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEV 2189 Query: 4147 -----RRGAGQEKVDREDKEQGKMDHEVEEQQKADGVGIEQGKMDGDKNEQERVLFLYLP 4201 RR +++ R DK + K +V+E + + E + + +QE Sbjct: 2190 IPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQE-------- 2241 Query: 4202 SNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSSETGKKANGVPSEGDSAS------ 4255 SL+ + R E EE ++ +R + +K E G++ E + Sbjct: 2242 ---SLSSEEEEEREEEEEREEEEVRE---EEEERKEEEEGEEKQVEKEEEEKKKKKKEKK 2295 Query: 4256 --EVQKAKDYMQQKEEDESKQETVLFLHLPSESSLTCYELNTRKEGEEDLQGIIKSATLQ 4313 EVQ+ ++ ++KEE S++ET L E +C L + E+++ K LQ Sbjct: 2296 KEEVQEKEEVFEEKEEIMSEEETE-SLSDEEEEEESC-SLEEEVDREKEILKKEKQFKLQ 2353 Query: 4314 LRQQKS 4319 +++KS Sbjct: 2354 EQRRKS 2359 Score = 34.7 bits (78), Expect = 3.4 Identities = 81/436 (18%), Positives = 167/436 (38%), Gaps = 39/436 (8%) Query: 487 SRKQLVKVMPGLIKCGHFLQKQNKSPDTEKINYAGPLEETGISDITKKEKEYDKENKRLK 546 + K+LV+V L K L ++ EK G G DI K+EK + E KRL Sbjct: 1912 TEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKALNLEMKRLA 1971 Query: 547 NISPKMLPQLEQSFMVNTVQLKAPCLLVETNG---KSKESLKDSIT--QAKGIGITEFHV 601 +++ E T + + + + K SL++ I + + + + E + Sbjct: 1972 EEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKILLHEDRILAMEESEI 2031 Query: 602 LNSKKPFDLHIPKHKTSLEEAISKPMQKLVSSPE---MESNNRMKIQEDLQSSENSHLQL 658 K F + + ++K +KL+ E E KI + LQ +L Sbjct: 2032 AKGKLEF-TRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLNKILKALQKLTRDERKL 2090 Query: 659 SNGEELPTSTPKT----QRCFPRENTQ---KQKDFLELVLELSNVGLLIS-----LGSKM 706 + E T + +R E ++ K+ DF E EL+ ++ L +KM Sbjct: 2091 TQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQRKLANKM 2150 Query: 707 HKSSEELEAIKIQVNTESVNLKESKPLILNVTEDSDLRESEEL-----------ECNTG- 754 + + E + ES ++ +IL+ E+ + E E + E G Sbjct: 2151 RRMINKEEKM---TEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGD 2207 Query: 755 ---SNITNMHQDKETSDAFHSATYTTISQLPDTETHSISKAKADTLRIIRLSHSASKQEK 811 ++ + E+ + F + + +L E+ S + + R ++E+ Sbjct: 2208 KPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEE 2267 Query: 812 LPDEKETQNAEYIDKSCTFKKPQQCDRKEQEKEANSELTQGFRFSIHLKQKPKYVKFQME 871 E+E + ++K KK ++ ++K++E + E+ + + ++ + E Sbjct: 2268 ERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEE 2327 Query: 872 QISSGSSKAPNKEQEV 887 + S + ++E+E+ Sbjct: 2328 EESCSLEEEVDREKEI 2343 Score = 33.5 bits (75), Expect = 7.6 Identities = 22/63 (34%), Positives = 34/63 (53%), Gaps = 8/63 (12%) Query: 5178 KRPILRRISHIGETVHRESVVGDIPKDVKNEKQHIPQKEERNQKKIIDMRG---TDITLK 5234 K+PI I E RE ++ + ++V K+ +P++EE+ QKK DM G T + LK Sbjct: 1314 KKPIF-----IQEGAIREDMIQGVTQEVIRHKEVMPREEEQAQKKARDMLGLEETQVILK 1368 Query: 5235 SKK 5237 K Sbjct: 1369 KGK 1371 >gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo sapiens] Length = 1938 Score = 54.3 bits (129), Expect = 4e-06 Identities = 117/587 (19%), Positives = 239/587 (40%), Gaps = 75/587 (12%) Query: 3756 KEPQRSNKKLEKMTQEDESNLNVVQNKLCASILSPPHLEWNPRIKEVYMRGITRFCLSSS 3815 +E + + KKL + QE E N +K CAS L ++++ MR + R + + Sbjct: 1388 EELEEAKKKLAQRLQEAEENTETANSK-CAS-LEKTKQRLQGEVEDL-MRDLERSHTACA 1444 Query: 3816 T----QQELSDTMEKCEQPIDDSLSSIEKAKHMPQ-------KDKDRVEKALEKIMHSKR 3864 T Q+ + + +Q +D+S + +E A+ + K ++ E+ ++++ +R Sbjct: 1445 TLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRR 1504 Query: 3865 IALEVKQPSIFQELELNIKEKGGKIQE-DKEVEIWSKPFASISFLPYSKVGTIEGEEAMR 3923 +++ +L I E G +QE +K ++ + + + G++E EE+ Sbjct: 1505 ENKNLQEE--ISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKI 1562 Query: 3924 IKMRSSFSQPNLQ-ESSDTEKTAYEKCISDNISNSVKKALESILQKEQRQKMEKIRALKK 3982 ++++ SQ + + EK + + N S +AL+S+L E R + + +R KK Sbjct: 1563 LRVQLELSQVKSELDRKVIEKDEEIEQLKRN-SQRAAEALQSVLDAEIRSRNDALRLKKK 1621 Query: 3983 MKSSISQ-GIQL-----DIKEQEKRIEHIKGEPSVLLTNACASIPSPSHLQLDTRREKAE 4036 M+ +++ IQL + E +K + ++G+ + ++ S L +E+ Sbjct: 1622 MEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDL-----KEQLA 1676 Query: 4037 YVTEITRYYLPELSHQKSSEAGEKADGVASKGDITIKVQKAKDYMQQKEDDEVKISAKKD 4096 V L EL K + +++ + + E + + S + Sbjct: 1677 IVERRNGLLLEELEEMK------------------VALEQTERTRRLSEQELLDASDRVQ 1718 Query: 4097 IMHPEDKGL-KAKKALSQDLPLNTKEPGKMDQE---AQEQGKE-----DREGEEQGKEDR 4147 ++H ++ L KK L D+ E QE A+E+ K+ EE KE Sbjct: 1719 LLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQD 1778 Query: 4148 RGAGQEKVDREDKEQGK-MDHEVEE-QQKADGVGIEQ-GKMDGDKNEQERVLFL------ 4198 A E++ + ++ K + H ++E +Q A G +Q K++ E E L + Sbjct: 1779 TSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLENRVRELENELDVEQKRGA 1838 Query: 4199 -YLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSSETGKKANGVPSEGDSASEV 4257 L + + + EED + I+R LQ K K E + + Sbjct: 1839 EALKGAHKYERKVKEMTYQAEEDHKNILR---LQDLVDKLQAKVKSYKRQAEEAEEQANT 1895 Query: 4258 QKAKDYMQQKEEDESKQETVLFLHLPSESSLTCYELNTRKEGEEDLQ 4304 Q ++ Q E +E+ + + +ES + +R G + ++ Sbjct: 1896 QLSRCRRVQHELEEAAERADI-----AESQVNKLRAKSRDVGSQKME 1937 Score = 44.7 bits (104), Expect = 0.003 Identities = 106/600 (17%), Positives = 246/600 (41%), Gaps = 90/600 (15%) Query: 3835 LSSIEKAKHMPQKDKDRVEKALEKIMHS--KRIALEVKQPSIFQE---LELNIKEKGGKI 3889 L S E K M +D E+ E++ S +R LE K S+ QE L+L ++ + + Sbjct: 844 LKSAEAEKEMATMKED-FERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENL 902 Query: 3890 QEDKEVEIWSKPFASISFLPYSKVGTIEGEEAMRIKMRSSFSQPNLQESSDTEKTAYEKC 3949 + +E G I+ + + K++ + +E ++E A ++ Sbjct: 903 MDAEE----------------RCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRN 946 Query: 3950 ISDNISNSVKKALESI------LQKEQRQKMEKIRALKKMKSSISQGIQLDIKEQEKRIE 4003 + D S S+K+ ++ + ++KE+ K++ L + +++ + I KE++ E Sbjct: 947 LEDKCS-SLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQE 1005 Query: 4004 -HIKGEPSVLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEAGEKAD 4062 H + + + + + +L+ + + E E + +L K G+ Sbjct: 1006 AHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKM 1065 Query: 4063 GVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDI-------MHPEDKGLKAK-KALSQD 4114 S D+ Q+ ++ +++KE + ++ AK D + K L+A+ + L ++ Sbjct: 1066 SQESIMDLENDKQQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEE 1125 Query: 4115 LPLNTKEPGKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVD------------REDKEQ 4162 + K++++ + +E E E+ E+ GA +++ R D E+ Sbjct: 1126 IEAEHTLRAKIEKQRSDLARELEEISER-LEEASGATSAQIEMNKKREAEFQKMRRDLEE 1184 Query: 4163 GKMDHEVE----EQQKADGVGIEQG-----------KMDGDKNEQERVL---------FL 4198 + HE +++AD V E G K++ +K+E + + Sbjct: 1185 ATLQHEATAATLRKKQADSVA-ELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALS 1243 Query: 4199 YLPSNSSLTHYILD---TRIEGEEDQQGIIRPGILQPRHQKSSETGKKANGVPSEGDSAS 4255 SN T ++ + I+ +++QQ + + + + ++ G+ ++ V + S Sbjct: 1244 KSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLIS 1303 Query: 4256 EVQKAK-------DYMQQKEEDESKQETVLFLHLPS---ESSLTCYELNTRKEGEEDLQG 4305 ++ K+K + ++++ E+E+K + + L S + L + +E + +LQ Sbjct: 1304 QLTKSKQALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQR 1363 Query: 4306 IIKSATLQLRQQKS-FDAGKIAHTKSFGVDSSNDVKTVQEYKPQKEVDRGKTVSVDYIMQ 4364 + A ++ Q ++ ++ I T+ + +QE + E K S++ Q Sbjct: 1364 ALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQ 1423 Score = 40.8 bits (94), Expect = 0.047 Identities = 79/382 (20%), Positives = 159/382 (41%), Gaps = 61/382 (15%) Query: 531 ITKKEKEYDKENKRLKNISPKMLPQLEQSFMVNTVQLKAPCLLVETNGKSKESLKDSITQ 590 +TK EKE ++KN+S +M LE++ T + K+ L E + ++ + L+ + + Sbjct: 965 LTKVEKEKHATENKVKNLSEEMTA-LEENISKLTKEKKS---LQEAHQQTLDDLQ--VEE 1018 Query: 591 AKGIGITEFHVLNSKKPFDLHIPKHKTSLEEAISKPMQKLVSSPEMESNNRMKIQEDLQS 650 K G+ + + ++ DL + SLE+ +KL + E + K++ DL+ Sbjct: 1019 DKVNGLIKINAKLEQQTDDL-----EGSLEQE-----KKLRADLERA---KRKLEGDLKM 1065 Query: 651 SENSHLQLSNGEELPTSTPKTQRCFPRENTQKQKDFLELVLELSNVGLLISLGSKMHKSS 710 S+ S + L N ++ K + F Q + D E V L + L +++ + Sbjct: 1066 SQESIMDLENDKQQIEEKLKKKE-FELSQLQAKIDD-EQVHSLQFQKKIKELQARIEELE 1123 Query: 711 EELEA---IKIQVNTESVNLKESKPLILNVTEDSDLRESEELECNTG--SNITNMHQDKE 765 EE+EA ++ ++ + +L I E++ S ++E N + M +D E Sbjct: 1124 EEIEAEHTLRAKIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLE 1183 Query: 766 TSDAFHSATYTTIS---------------------------------QLPDTETH--SIS 790 + H AT T+ ++ D ++ ++S Sbjct: 1184 EATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALS 1243 Query: 791 KAKADTLRIIRLSHSASKQEKLPDEKETQNAEYIDKSCTFKKPQQCDRKEQEKEANSELT 850 K+K++ R R + K DE++TQ ++ + Q + + +E S ++ Sbjct: 1244 KSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLIS 1303 Query: 851 QGFRFSIHLKQKPKYVKFQMEQ 872 Q + L Q+ + +K QME+ Sbjct: 1304 QLTKSKQALTQQLEELKRQMEE 1325 Score = 33.1 bits (74), Expect = 9.9 Identities = 26/109 (23%), Positives = 48/109 (44%), Gaps = 18/109 (16%) Query: 2752 SNKKELRGNIQQ-----QKSFQLSKNAVHRVLKAVYDSGYCVSSIKKLTEVKMEKDKPKD 2806 + KK+L +I Q + S Q S+NA + KA+ D+ +KK + ++ K Sbjct: 1729 NTKKKLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMK- 1787 Query: 2807 RTCILPQPKLEKPLKEMQRSLSGCTDMS-----SILRKQEQDIREKEQK 2850 LE+ +K++Q L ++ ++K E +RE E + Sbjct: 1788 -------KNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLENRVRELENE 1829 >gi|84043963 eukaryotic translation initiation factor 5B [Homo sapiens] Length = 1220 Score = 53.9 bits (128), Expect = 5e-06 Identities = 81/396 (20%), Positives = 172/396 (43%), Gaps = 56/396 (14%) Query: 3840 KAKHMPQKDKDRVEKALEKIMHSKRIALEVKQPSIFQELELNIKEKGGKIQEDKEVE--- 3896 K K + QK ++ E+ +K K ++K+ +ELE K++ + + ++ E Sbjct: 224 KIKTVAQKKAEKKERERKKRDEEKAKLRKLKEK---EELETGKKDQSKQKESQRKFEEET 280 Query: 3897 IWSKPFASISFLPYSKVGT-----IEGEEAMRIKMRSSFSQPNLQESSDTEKTAYEKCIS 3951 + SK +P S+ E + K + + +E + EK +K S Sbjct: 281 VKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEK---KKGPS 337 Query: 3952 DNISNSVKKALESILQKEQRQKMEKIRALKKMKSSISQGIQLDIKEQEKRI--------- 4002 ++++AL + ++E+RQK E+ +K+++ ++ + + EQEKR Sbjct: 338 KATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKER 397 Query: 4003 -EHIKGEPSVLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLP------ELSHQKSS 4055 E +K E +L + + + + + +A+ V ++ LP E +K Sbjct: 398 KERLKKEGKLLTKS---QREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKI 454 Query: 4056 EAGEKADGVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQD- 4114 ++ V+ ++ V+ + + +KE+ + +++ ED GL +A++ D Sbjct: 455 PQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEE-EDTEDAGLDDWEAMASDE 513 Query: 4115 ---------LPLNTKEPGKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDRED------ 4159 + + KE + ++E +E+ +ED E EE+ +E+ G E D ED Sbjct: 514 ETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEG-DEEDEKVSDE 572 Query: 4160 KEQGK-MDHEVEEQQKADGVGIEQGKMDGDKNEQER 4194 K+ GK +D + ++ +D + D D+ ++ER Sbjct: 573 KDSGKTLDKKPSKEMSSD----SEYDSDDDRTKEER 604 Score = 49.7 bits (117), Expect = 1e-04 Identities = 83/405 (20%), Positives = 171/405 (42%), Gaps = 53/405 (13%) Query: 3817 QQELSDTMEKCEQPIDDSLSSIEKA----KHMPQKDKDRVEKALEKIMHSKRIALEVKQP 3872 Q+ S+ K + +D + IE A + PQK K + +K +K + + Sbjct: 5 QKNKSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKK--------QDFDED 56 Query: 3873 SIFQELE-LNIKEKGGKIQEDKEVEIWSKPFASISFLPYSKVGTIEGEEAMRIKMRSSFS 3931 I +ELE L+++ +G I+ D+E + KP + SK +G++ + + S Sbjct: 57 DILKELEELSLEAQG--IKADRET-VAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDS 113 Query: 3932 QPNLQESSDTEKTA------YEKCISDNISNSVKKALESILQK---------EQRQKMEK 3976 + + S ++KTA Y D+ N + K + QK E +K Sbjct: 114 EELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKK 173 Query: 3977 IRALKKMKSSISQGIQLD----IKEQEKRIEHIKGEPSVLLTNACASIPSPSHLQLDTRR 4032 I+ ++ SS G + D ++ +K+ + K P++ N + ++ T Sbjct: 174 IKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNE----DDDASFKIKTVA 229 Query: 4033 EKAEYVTEITRYYLPELSHQKSSEAGEKADGVASKGDI-TIKVQKAKDYMQQKEDDEVKI 4091 +K E R +K E K + K ++ T K ++K Q++ +E + Sbjct: 230 QKKAEKKERER--------KKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETV 281 Query: 4092 SAKKDIMHPEDKGLKAKKALSQDLPLNTKEPGKMDQEAQEQGKEDREGEEQGKEDRRGAG 4151 +K + D G+ + P ++ + D++ +++ K+ E EE+ KE ++G Sbjct: 282 KSKVTV----DTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPS 337 Query: 4152 QEKVDREDKEQGKMDHEVEEQQKADGVGIEQ-GKMDGDKNEQERV 4195 + V + K+ E E Q++ + I++ +++ + E+ER+ Sbjct: 338 KATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERL 382 Score = 41.2 bits (95), Expect = 0.036 Identities = 75/385 (19%), Positives = 147/385 (38%), Gaps = 43/385 (11%) Query: 3920 EAMRIKMRSSFSQPNLQESSDTEKTAYEKCISDNISNSVKKALESILQKEQRQKMEKIRA 3979 +A+ ++ + + + K EK D + + K LE + + Q K ++ Sbjct: 20 DALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKELEELSLEAQGIKADRETV 79 Query: 3980 LKKMKSSISQGIQLDIKEQEKRIEHIKGEPSVLLTNACASIPSPSHLQLDTRREKAEYVT 4039 K + + + ++K+ + KG+ N + T + K E Sbjct: 80 AVKPTENNEE----EFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEM-- 133 Query: 4040 EITRYYLPELSHQKSSEAGEKADGVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDIMH 4099 Y ++ +KA G A K + K D ++ ED+ KI + I Sbjct: 134 -----YSGSDDDDDFNKLPKKAKGKAQKSN------KKWDGSEEDEDNSKKIKERSRINS 182 Query: 4100 PEDKGLKAKKALSQDLPLNTKEPGKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDRED 4159 + G ++ + L + K E G ED + + K Q+K ++++ Sbjct: 183 SGESGDESDEFLQSRKGQKKNQKNKPGPNI-ESGNEDDDASFKIKT----VAQKKAEKKE 237 Query: 4160 KEQGKMDHEVEEQQKA-DGVGIEQGKMDGDKNEQERVLFLYLPSNSSLTHYILDTRIEGE 4218 +E+ K D E + +K + +E GK D K ++ + F S +T +DT Sbjct: 238 RERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVT---VDT----- 289 Query: 4219 EDQQGIIRPGILQPRHQKSSETGKKANGVPSEGDSAS-EVQKAKDYMQQKEEDESKQETV 4277 G+I P ++ +ET A +EGD + +K K ++KE+++ K + Sbjct: 290 ----GVI------PASEEKAETPTAAED-DNEGDKKKKDKKKKKGEKEEKEKEKKKGPSK 338 Query: 4278 LFLHLPSESSLTCYELNTRKEGEED 4302 + E+ E R++ EE+ Sbjct: 339 ATVKAMQEALAKLKEEEERQKREEE 363 Score = 37.4 bits (85), Expect = 0.52 Identities = 100/525 (19%), Positives = 187/525 (35%), Gaps = 70/525 (13%) Query: 368 QLRSVKAQGQQQIVSSELNQDSVYSSVPLLSTIKGQKNRRKTPDSKSKLSLNVPSLKAKK 427 + + +KA + V N + ++S KGQK ++++ D L K+KK Sbjct: 68 EAQGIKADRETVAVKPTENNEEEFTSKDKKK--KGQKGKKQSFDDNDSEELEDKDSKSKK 125 Query: 428 TPTSQVFQITVCHTLKNRNELGCKNNTEKKELHERKDISDIALHLISVSKLILPYVKNYS 487 T +V + + N+L K + ++ +++ D S+ ++ Sbjct: 126 TAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSE----------------EDED 169 Query: 488 RKQLVKVMPGLIKCGH-------FLQKQNKSPDTEKINYAGPLEETGISD---------- 530 + +K + G FLQ + +K N GP E+G D Sbjct: 170 NSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQK-NKPGPNIESGNEDDDASFKIKTV 228 Query: 531 ----ITKKEKEY---DKENKRLKNISPKMLPQLEQSFMVNTVQLKAPCLLVETNGKSKES 583 KKE+E D+E +L+ + K +LE + Q ++ E KSK + Sbjct: 229 AQKKAEKKERERKKRDEEKAKLRKLKEK--EELETGKKDQSKQKESQRKFEEETVKSKVT 286 Query: 584 LKDSIT-----QAKGIGITEFHVLNSKKPFDLHIPK-HKTSLEEAISKPMQKLVSSPEME 637 + + +A+ E KK D K K E+ K K E Sbjct: 287 VDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQE 346 Query: 638 SNNRMKIQEDLQSSENSHLQLSNGEELPTSTPKTQRCFPRENTQKQKDFLELVLELSNVG 697 + ++K +E+ Q E ++ EEL + +R + +K++ E L G Sbjct: 347 ALAKLKEEEERQKREEEE-RIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEG 405 Query: 698 LLISLGSKMHKSSEELEAIKIQVNTESVNLKESKPLILNVTEDSDLRE-SEELECNTGSN 756 L++ + ++ E +Q V K+S P + ED ++ ++LE S Sbjct: 406 KLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSE 465 Query: 757 ITNMHQDKETSDAFHSATYTTISQLPDTETHSISKAKADTLRIIRLSHSASKQE------ 810 + E + T + E A D + K E Sbjct: 466 SMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHI 525 Query: 811 ---KLPDEKETQNAEYIDKSCTFKKPQQCDRKEQEKEANSELTQG 852 + P+E+E + E ++ + +E+E+E SE ++G Sbjct: 526 EVKENPEEEEEEEEE--------EEEDEESEEEEEEEGESEGSEG 562 Score = 36.2 bits (82), Expect = 1.2 Identities = 59/363 (16%), Positives = 156/363 (42%), Gaps = 34/363 (9%) Query: 3933 PNLQESSDTEKTAYE-KCISDNISNSVKKALESILQKEQRQKMEKIRALKKMKSSISQGI 3991 PN++ ++ + +++ K ++ + KK E + E++ K+ K++ +++++ Sbjct: 210 PNIESGNEDDDASFKIKTVAQK--KAEKKERERKKRDEEKAKLRKLKEKEELETGKKD-- 265 Query: 3992 QLDIKEQEKRIEH--IKGEPSV---LLTNACASIPSPSHLQLDTRREKAEYVTEITRYYL 4046 Q KE +++ E +K + +V ++ + +P+ + D +K + + + Sbjct: 266 QSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEK 325 Query: 4047 PELSHQKSSEAGEKADGVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLK 4106 E +K + G V + + K+++ ++ +++E++ +K + + E++ L+ Sbjct: 326 EE--KEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLE 383 Query: 4107 A-----KKALSQDLPLNTKEPGKMDQEAQEQGKEDREG-----EEQGKE--DRRGAGQEK 4154 KK ++ K+ GK+ ++Q + + E + QG E + +++ Sbjct: 384 QEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKR 443 Query: 4155 VDREDKEQGKMDHEVEEQQKADGVGIEQGK--MDGDKNEQERVLFLYLPSNSSLTHYILD 4212 EDK++ K+ ++E ++ ++ + + M+ E+E P D Sbjct: 444 PIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEE------D 497 Query: 4213 TRIEGEEDQQGIIRPGILQPRHQKSSETGKKANGVPSEGDSASEVQKAKDYMQQKEEDES 4272 T G +D + + + K N P E + E ++ + +++EE+E Sbjct: 498 TEDAGLDDWEAMASDEETEKVEGNKVHIEVKEN--PEEEEEEEEEEEEDEESEEEEEEEG 555 Query: 4273 KQE 4275 + E Sbjct: 556 ESE 558 >gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 899 Score = 53.5 bits (127), Expect = 7e-06 Identities = 94/493 (19%), Positives = 208/493 (42%), Gaps = 68/493 (13%) Query: 3721 KKEDR--ENIVDVKDIMGLKCITLKGKKSLFRHLLHGKEPQRSNKKLEKM-----TQEDE 3773 KK DR E + +D + L+ L+R+ + +E ++ N +L++ +++ E Sbjct: 193 KKADRYIEELTKERDALSLE---------LYRNTITNEELKKKNAELQEKLPLAESEKSE 243 Query: 3774 SNLNV--VQNKLCASILSPPHLEWNPRIKEVYMRGITRFCLSSSTQQELSDTMEKCEQPI 3831 LNV ++ KL + P ++ N +E++ + ++EL + +K + Sbjct: 244 IQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQ-----------EEELREQEKKIRKQE 292 Query: 3832 DDSLSSIEKAKHMPQKDKDRVEKAL--EKIMHSKRIALEVKQPSIFQELELNIKEKGGKI 3889 + E+ + K +++ EK EK + + L ++ + ++ EL +E+ + Sbjct: 293 EKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQE 352 Query: 3890 QEDKEVEIWSKPFASISFLPYSKVGTIEGEEAMRIKMRSSFSQPNLQESSDTEKTAYEKC 3949 QE+K +W E EE MR + + Q + + E+ Sbjct: 353 QEEK---MW------------------EQEEKMREQEEKMWRQEERLWEQEKQMREQEQK 391 Query: 3950 ISDNISNSVKKALESILQKEQR--------QKMEKIRALKKMKSSISQGIQLDIKEQEKR 4001 + D ++ E + +KE+R +++EK+R KKM+ + + K QE+ Sbjct: 392 MRDQEERMWEQD-ERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEE- 449 Query: 4002 IEHIKGEPSVLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEAGEKA 4061 E I+ + +Q ++E+ + E + L QK + E+ Sbjct: 450 -ERIREREKKMREEEETMREQEEKMQ---KQEENMWEQEEKEWQQQRLPEQKE-KLWEQE 504 Query: 4062 DGVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPLNTKE 4121 + I + +K +D ++ E K+ ++ + ED+ + ++ + + Sbjct: 505 KMQEQEEKIWEQEEKIRD-QEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQ 563 Query: 4122 PGKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADGVGIE 4181 +M+++ QEQ K+ + EE+ +E+ R +EK RE++E + E ++Q+ E Sbjct: 564 EERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQE 623 Query: 4182 QGKMDGDKNEQER 4194 + + ++ QE+ Sbjct: 624 EKMWEQEEKMQEQ 636 Score = 42.0 bits (97), Expect = 0.021 Identities = 73/379 (19%), Positives = 166/379 (43%), Gaps = 60/379 (15%) Query: 3819 ELSDTMEKCEQPIDDSLSSIEK-AKHMPQKDKDRVEKALEKIMHSKRIALEVKQPSIFQE 3877 E + M EQ + D +EK + +K D+ EK E+ +R ++ + +E Sbjct: 548 EQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMRE 607 Query: 3878 LELNIKEKGGKIQEDKEVEIWSKPFASISFLPYSKVGTIEGEEAMRIKMRSSFSQPNLQE 3937 E ++E+ K+QE +E ++W E EE M+ + + Q ++ Sbjct: 608 QEEKMQEQEEKMQEQEE-KMW------------------EQEEKMQEQEEKMWEQE--EK 646 Query: 3938 SSDTEKTAYEKCISDNISNSVKKALESILQKEQRQKMEKIRALKKMKSSISQGIQLDIKE 3997 + E+ +E+ + + E + + E+ Q+ EK++ ++ K + ++ +E Sbjct: 647 MWEQEEKMWEQ-------QRLPEQKEKLWEHEKMQEQEKMQEQEE-KIWEQEKMEKKTQE 698 Query: 3998 QEKRI---EHIKGEPSVLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKS 4054 QEK+ E ++ E S+ + + RE+ E + E E ++ Sbjct: 699 QEKKTWDQEKMREEESM------REREKKMREEEEMMREQEEKMQE-----QEEKMQEQE 747 Query: 4055 SEAGEKADGVASKGDIT-----IKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAK- 4108 E E+ + + + + + QK K + +K ++ KI +++ M +++ ++ + Sbjct: 748 EEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQE 807 Query: 4109 -KALSQDLPLNTKEPGKMDQEAQEQGKEDRE--------GEEQGKEDRRGAGQEKV-DRE 4158 K Q+ + +E QE + G+E++ G+E+ E++ +EK+ ++E Sbjct: 808 EKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQE 867 Query: 4159 DKEQGKMDHEVEEQQKADG 4177 +K +G+ + E+++K G Sbjct: 868 EKMRGQEEKMREQEEKMRG 886 Score = 35.8 bits (81), Expect = 1.5 Identities = 72/359 (20%), Positives = 152/359 (42%), Gaps = 38/359 (10%) Query: 3828 EQPIDDSLSSIEKAKHMPQKDKDRVEKALEKIMHSKRIALEVK---QPSIFQELELNIKE 3884 E+ + + ++ + + QK ++ + + EK +R+ + + + QE E I E Sbjct: 456 EKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWE 515 Query: 3885 KGGKIQEDKEVEIWSKPFASISFLPYSKVGTIEGEEAMRIKMRSSFSQPNLQESSDTEKT 3944 + KI++ +E+ K + + E EE MR + + + Q E E+ Sbjct: 516 QEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQ- 574 Query: 3945 AYEKCISDNISNSVKKALESILQKEQRQKMEKIRALKKMKSSISQGIQLDIKEQEKRI-- 4002 EK D +K E +E+ +KM + + + + Q + ++EQE+++ Sbjct: 575 --EKKTWDQ----EEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWE 628 Query: 4003 --EHIKGEPSVLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLPELS-----HQKSS 4055 E ++ + + Q + E+ E + E R LPE H+K Sbjct: 629 QEEKMQEQEEKMWE------------QEEKMWEQEEKMWEQQR--LPEQKEKLWEHEKMQ 674 Query: 4056 EAGEKADGVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDL 4115 E EK K K++K ++K D+ K+ +++ M +K ++ ++ + ++ Sbjct: 675 EQ-EKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMR-EEESMREREKKMREEEEMMREQ 732 Query: 4116 PLNTKEPGKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQK 4174 +E +++ QEQ +E E EE+ E +++ E KE+ +++EQ+K Sbjct: 733 EEKMQE---QEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEK 788 Score = 33.9 bits (76), Expect = 5.8 Identities = 92/503 (18%), Positives = 216/503 (42%), Gaps = 57/503 (11%) Query: 3713 ESKCFPQKK--KEDRENIVDVKDIMGLKCITLKGKKSLFRHLLHGKEPQRSNKKLEKMTQ 3770 E + + Q+K +E + + D ++ M + L+ K+ R E ++ +++EKM + Sbjct: 375 EERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMR------EQEKMWEQVEKMRE 428 Query: 3771 EDESNLNVVQNKLCASILSPPHLEWNPRIKEVYMRGITRFCLSSSTQQELSDTMEKCEQP 3830 E + Q K E R +E MR T +E + M+K E+ Sbjct: 429 EKKMQ---EQEKKTRDQEEKMQEEERIREREKKMRE------EEETMREQEEKMQKQEEN 479 Query: 3831 IDDSLSSIEKAKHMPQK-----DKDRVEKALEKIMHSKRIALEVKQ----------PSIF 3875 + + + + +P++ +++++++ EKI + + ++ Sbjct: 480 MWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKM 539 Query: 3876 QELELNIKEKGGKIQEDKEVEIWSKPFASISFLPYSKVGTIEGEEAMRIKMRSSFSQPNL 3935 +E E + E+ K++ D+E ++W + + T + EE MR + R + + Sbjct: 540 REQEDQMWEQEEKMR-DQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKM 598 Query: 3936 QESSDTEKTAYEKCIS--DNISNSVKKALESI--LQKEQRQKMEKIRALKKMKSSISQGI 3991 +E + + EK + + +K E +Q+++ + E+ + + + + + Sbjct: 599 REEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQ 658 Query: 3992 QLDIKEQEKRIEHIKGEPSVLLTNACASIPSPSHLQLDTR-REKAEYVTEITRYYLPELS 4050 +L +++EK EH K + + I ++ T+ +EK + E R E Sbjct: 659 RLP-EQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMRE--EESM 715 Query: 4051 HQKSSEAGEKADGVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAKKA 4110 ++ + E+ + + + + K+Q+ ++ MQ++E++ + K + E+K + ++ Sbjct: 716 REREKKMREEEEMMREQEE---KMQEQEEKMQEQEEEMWEQEEK--MWEQEEKMWEQQRL 770 Query: 4111 LSQDLPLNTKEPGKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDR--EDKEQGKMDHE 4168 Q KE ++ QEQ K + E+ ++ + GQE+ R E+K +G+ + Sbjct: 771 PEQ------KEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKM 824 Query: 4169 VEEQQKADGVGIEQGKMDGDKNE 4191 +++K G ++ KM G + + Sbjct: 825 WGQEEKMWG---QEEKMWGQEEK 844 >gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] Length = 793 Score = 53.5 bits (127), Expect = 7e-06 Identities = 116/610 (19%), Positives = 244/610 (40%), Gaps = 110/610 (18%) Query: 3813 SSSTQQELSDTMEKCEQPIDDSLSSIEKAKHMPQKDKDRVEKALEKIMHSKRIALEVKQP 3872 +S +E T + DD + +E+ ++ + R+++ALE+ Sbjct: 72 NSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALER-------------- 117 Query: 3873 SIFQELELNIKEKGGKIQEDKEVEIWSKPFASISFLPYSKVGTIEGEEAMRIKMRSSFSQ 3932 +E + I + AS+S LP ++ E K S S+ Sbjct: 118 --QKEFDPTITD------------------ASLS-LPSRRMQNDTAENETTEKEEKSESR 156 Query: 3933 PNLQESSDTEKT--AYEKCISDNISNSVKKALESILQKEQRQKMEKIRALKKMKSSISQG 3990 E +TE +Y+K N + A E+ +KE ++K E+ K + SI + Sbjct: 157 QERYEIEETETVTKSYQK-------NDWRDAEEN--KKEDKEKEEE-EEEKPKRGSIGEN 206 Query: 3991 IQLDIKEQEKRIEHIKGEPSVLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLPELS 4050 Q+++ +EK E E +V+++ I S Q + R + ++ E+S Sbjct: 207 -QVEVMVEEKTTE--SQEETVVMSLKNGQISSEEPKQEEEREQGSD-----------EIS 252 Query: 4051 HQKSSEAGEKADGVASKGDITIKVQKAKDYMQQKE--DDEVKISAKKDIMHPEDKGLKAK 4108 H + E +K A + + + ++ Q K+ D+ +I A++ E + +A+ Sbjct: 253 HHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAE 312 Query: 4109 KALSQDLPLNTKEPGKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHE 4168 + + + K + Q +E+ K E ++ KE+ + A +E+ +++E+ Sbjct: 313 E--RERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEK----RA 366 Query: 4169 VEEQQKADGVGIEQGKMDGDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPG 4228 EE+Q+A E+ K++ K ++ H + +T+I+GE+ +Q I Sbjct: 367 AEERQRARAEEEEKAKVEEQKRNKQL---------EEKKHAMQETKIKGEKVEQKIEGKW 417 Query: 4229 ILQPRHQKSSETGKKANGVPSEG-DSASEVQKAKDYMQQKEEDESKQETVLFLHLPSESS 4287 + +K+ E + + +G + ++VQ ++ +Q+ + K+E Sbjct: 418 V---NEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEE------------ 462 Query: 4288 LTCYELNTRKEGEEDLQGII---KSATLQLRQQKSFDAGKIAHTK-SFGVDSSNDVKTVQ 4343 + ++ KE +E+++ + K T Q F K+ HT+ +F + Sbjct: 463 IKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTK 522 Query: 4344 EYKPQKEVDRGKTVSVDYIMQPEGTIFEAEQLSLPHTLNIPGSSGSKTREVLTNIKEKLR 4403 E + +V+ GK + + E E E+L K +E ++E + Sbjct: 523 EAEGAPQVEAGKRLEELRRRRGETESEEFEKLK------------QKQQEAALELEELKK 570 Query: 4404 HVQERKSELD 4413 +ER+ L+ Sbjct: 571 KREERRKVLE 580 Score = 49.7 bits (117), Expect = 1e-04 Identities = 83/407 (20%), Positives = 170/407 (41%), Gaps = 42/407 (10%) Query: 3825 EKCEQPIDDSLSSIEKAKHMPQKDKDRVEKALEKIMHSKRIALEVKQPSIFQELELNIKE 3884 EK E+ D + E+A+ + ++++R++ +K + +R +E ++ + QE E E Sbjct: 255 EKMEEE-DKERAEAERAR-LEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAE 312 Query: 3885 KGGKIQEDKEVEIWSKPFASISFLPYSKVGTIEGEEAMRIKMRSSFSQPNLQESSDTEKT 3944 + +++E+++ A+ + EE RIK + Q + EK Sbjct: 313 ERERMREEEKR-------AAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKR 365 Query: 3945 AYEKCISDNISNSVKKALESILQKEQRQKMEKIRALKKMKSSISQGIQLDIKEQEKRIEH 4004 A E+ K +E QK +Q EK A+++ K +G +++ K + K + Sbjct: 366 AAEERQRARAEEEEKAKVEE--QKRNKQLEEKKHAMQETKI---KGEKVEQKIEGKWVNE 420 Query: 4005 IKGEPSVLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEAGEKADGV 4064 K + L T ++ +REK + + + E+ +K + E + V Sbjct: 421 KKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQ--EDKPTFKKEEIKDEKIKKDKEPKEEV 478 Query: 4065 AS-----KGDITIKVQKAKDYMQQKEDDEVKIS-----AKKDIMHPE-----DKGLKAKK 4109 S KG +K Q + + + E S A D E + G + ++ Sbjct: 479 KSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEE 538 Query: 4110 ALSQDLPLNTKEPGKMDQEAQEQGKE----DREGEEQGK---EDRRGAGQEKVDR---ED 4159 + ++E K+ Q+ QE E ++ EE+ K E+ + QE+ DR E+ Sbjct: 539 LRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREE 598 Query: 4160 KEQGKMDHEVEEQQKADGVGIEQGKMDGDKNEQERVLFLYLPSNSSL 4206 +E+ ++ E+ E+++A+ Q + ++ ++ + P SSL Sbjct: 599 EEKRRLKEEI-ERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSL 644 Score = 41.6 bits (96), Expect = 0.028 Identities = 92/501 (18%), Positives = 189/501 (37%), Gaps = 63/501 (12%) Query: 3940 DTEKTAYEKCISDNISNSVKKALESILQKEQRQKMEKIRALKKMKSSISQGIQLDIKEQE 3999 + E+ AY++ D+ + ++ Q+ RQK E+ +L ++ + Q + ++E Sbjct: 21 EAERIAYQRN-DDDEEEAARERRRRARQERLRQKQEE-ESLGQVTDQVEVNAQNSVPDEE 78 Query: 4000 KRIE----HIKGEPSVLLTNACASIPSPSHLQLDTRREKA-EYVTEIT--------RYYL 4046 + ++G+ A +L E+ E+ IT R Sbjct: 79 AKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQ 138 Query: 4047 PELSHQKSSEAGEKADGVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLK 4106 + + +++E EK++ + +I K Y Q+ + + + + K+D E++ K Sbjct: 139 NDTAENETTEKEEKSESRQERYEIEETETVTKSY-QKNDWRDAEENKKEDKEKEEEEEEK 197 Query: 4107 AKKALSQDLPLNTKEPGKMDQEAQE-------QGKEDREGEEQGKEDRRGAGQ----EKV 4155 K+ + + K + +E G+ E +Q +E +G+ + EK+ Sbjct: 198 PKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKM 257 Query: 4156 DREDKEQGKMDHEVEEQQKADGVGIEQGKMDGDKNEQERVLFLYLPSNSSLTHYILDTRI 4215 + EDKE+ + + E ++ + + EQ K D+ RI Sbjct: 258 EEEDKERAEAERARLEAEERERIKAEQDKKIADER----------------------ARI 295 Query: 4216 EGEEDQQGIIRPGILQPRHQKSSETGKKANGVPSEGDSASEVQKAKDYMQQKEEDESKQE 4275 E EE R ++ E K+A E E +K +Q+ ++E K+ Sbjct: 296 EAEEKAAAQERERREAEERERMREEEKRA---AEERQRIKEEEKRAAEERQRIKEEEKRA 352 Query: 4276 TVLFLHLPSESSLTCYELNTRKEGEEDLQGIIKSATLQLRQQKSFDAGKIAHTKSFGVDS 4335 + E E R EE+ + ++ + ++ A + K V+ Sbjct: 353 AEERQRIKEEEKRAAEE-RQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQ 411 Query: 4336 SNDVKTVQEYKPQKEVDRGKTVSVDYIMQPEGTIFEAEQLSLPHTLNIPGSSGSKTREVL 4395 + K V E K Q+ D+ +T + + +GT +A++ L K E+ Sbjct: 412 KIEGKWVNEKKAQE--DKLQTAVLKKQGEEKGTKVQAKREKLQE-----DKPTFKKEEIK 464 Query: 4396 TNIKEKLRHVQERKSELDVFL 4416 EK++ +E K E+ F+ Sbjct: 465 ---DEKIKKDKEPKEEVKSFM 482 >gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 668 Score = 53.1 bits (126), Expect = 9e-06 Identities = 91/463 (19%), Positives = 200/463 (43%), Gaps = 71/463 (15%) Query: 3719 QKKKEDR--ENIVDVKDIMGLKCITLKGKKSLFRHLLHGKEPQRSNKKLEKMTQEDESNL 3776 QKKK DR E + +D + L+ L+R+ + +E + N KL++ Q ES Sbjct: 187 QKKKADRYIEELTKERDALSLE---------LYRNTITDEELKEKNAKLQEKLQLVESEK 237 Query: 3777 NVVQNKLCASILSPPHLEWNPRIKEVYMRGITRFCLSSSTQQELSDTMEKCEQPIDDSLS 3836 + +Q L+ L+ ++ + + +EL K + ++++ Sbjct: 238 SEIQ-------LNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEEN-- 288 Query: 3837 SIEKAKHMPQKDKDRVEKALEKIMHSKRIALEVKQPSIFQELELNIKEKGGKIQEDKEVE 3896 E + Q+ ++++ + EKI + E Q +E E I+E+ K++ +E+ Sbjct: 289 --ELWNRLNQQQEEKMWRQEEKIQEWEEKIQE--QEEKIREQEEKIREQEEKMRRQEEM- 343 Query: 3897 IWSKPFASISFLPYSKVGTIEGEEAMRIKMRSSFSQPNLQESSDTEKTAYEKCISDNISN 3956 +W K EE MR + + + ++ E+ +EK + I Sbjct: 344 MWEK------------------EEKMRRQEEMMWEKE--EKMRRLEEMMWEK--EEKIRE 381 Query: 3957 SVKKALESIL---QKEQRQKMEKIRALKKMKSSISQGIQLD--IKEQEKRIEHIKGEPSV 4011 +K E Q+E+RQ+ EKIR +K + ++ + + I+EQE++I E Sbjct: 382 LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR----EQEK 437 Query: 4012 LLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEAGEKADGVASKGDIT 4071 + I ++ + +R++ E + + E ++ E + + + + I Sbjct: 438 KMWRQEEKIHEQEKIREEEKRQEQEEM------WRQEEKIREQEEIWRQKEKMHEQEKIR 491 Query: 4072 IKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPLNTKEPGKMDQEAQE 4131 + +K ++ D E KI +++ M +++ ++ Q+ + +E +QE Sbjct: 492 KQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIR-----EQEEKIREQEEKIREQEEMM 546 Query: 4132 QGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQK 4174 Q +E++ GE++ K QEK+ R++++ + + ++ EQ++ Sbjct: 547 QEQEEKMGEQEEKMQE----QEKMRRQEEKIREQEEKIREQKE 585 Score = 40.8 bits (94), Expect = 0.047 Identities = 80/432 (18%), Positives = 186/432 (43%), Gaps = 52/432 (12%) Query: 3755 GKEPQRSNKKLEKMTQEDE--SNLNVVQNKLCASILSPPHLEWNPRIKEVYMRGITRFCL 3812 GKE Q + KL+ +E+E + LN Q + EW +I+E + Sbjct: 271 GKELQSVSAKLQAQVEENELWNRLNQQQEEKMWR-QEEKIQEWEEKIQEQE----EKIRE 325 Query: 3813 SSSTQQELSDTMEKCEQPIDDSLSSIEKAKHMPQKDKDRVEKALEKIMHSKRIALEVKQP 3872 +E + M + E+ + + + + + M + ++++ + E + + E+++ Sbjct: 326 QEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEK 385 Query: 3873 SIFQELELNIKEKGGKIQEDKEVEIWSKPFASISFLPYSKVGTIEGEEAMRIKMRSSFSQ 3932 QE I+E+ K QE++++ K + + + E EE +R + + + Q Sbjct: 386 MHEQE---KIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQ 442 Query: 3933 PNL---QESSDTEKTAYEKCISDNISNSVKKALESILQKEQRQKMEKIRALKKM---KSS 3986 QE E+ E+ +++ E QKE+ + EKIR ++ + Sbjct: 443 EEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEE 502 Query: 3987 ISQGIQLDIKEQEKRIEHIKGEPSVLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYL 4046 + I+EQE+++ + E + Q + RE+ E + E Sbjct: 503 KMHDQEEKIREQEEKMW--RQEEKI-------------REQEEKIREQEEKIRE-----Q 542 Query: 4047 PELSHQKSSEAGEKADGVASKGDITIKVQKAKDYMQQKE---DDEVKISAKKD-IMHPED 4102 E+ ++ + GE+ + K+Q+ + +Q+E + E KI +K+ I E+ Sbjct: 543 EEMMQEQEEKMGEQEE----------KMQEQEKMRRQEEKIREQEEKIREQKEKIREQEE 592 Query: 4103 KGLKAKKALSQDLPLNTKEPGKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQ 4162 K + ++ + + + ++ KM ++ ++ +++ + +EQ ++ RR +EK+ ++ Sbjct: 593 KIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRR--QEEKMWEQEVRL 650 Query: 4163 GKMDHEVEEQQK 4174 + + +++E Q+ Sbjct: 651 RQQEEKMQEHQE 662 Score = 34.3 bits (77), Expect = 4.4 Identities = 86/471 (18%), Positives = 184/471 (39%), Gaps = 69/471 (14%) Query: 2503 KNKNGKESLKVGLARMEKSD---NCAELSEATDDAI------SNKYDKQNIGHSVLKENA 2553 K KN K K+ L EKS+ N EL + A + + ++G + +A Sbjct: 220 KEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSA 279 Query: 2554 FCNLAAIVPDSVGRHSPASEE-MKRQNGRLK-MADRSSPQGRPLQAKQSAVSQSPDTAGY 2611 + R + EE M RQ +++ ++ Q ++ ++ + + + Sbjct: 280 KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKM-- 337 Query: 2612 AVVSNNKEQKQNFKAQKTEAEVDLI-DQEAKINVAEEFNPESVFFSKIHPLQ--IENKKE 2668 +E+ K +K + +++ ++E K+ EE E KI L+ + +++ Sbjct: 338 ----RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKE--EKIRELEEKMHEQEK 391 Query: 2669 FKTADWKTRADPKTFALPKKQQELCVSGTIWSYPNPYTSISPKIIRHKDKAKTADVESTM 2728 + + K + + K K+Q++ +W KI R ++K E Sbjct: 392 IREQEEKRQEEEKIREQEKRQEQ---EAKMWRQEEKIREQEEKI-REQEKKMWRQEEKIH 447 Query: 2729 HTKQIKLKAKRIPVSQLLEYGTASNKKELRGNIQQQKSFQLSKNAVHRVLKAVYDSGYCV 2788 ++I+ + KR ++ I++Q+ K +H K Sbjct: 448 EQEKIREEEKRQEQEEMWRQ---------EEKIREQEEIWRQKEKMHEQEK--------- 489 Query: 2789 SSIKKLTE-VKMEKDKPKDRTCILPQPKLEKPLKEMQRSLSGCTDMSSILRKQEQDIREK 2847 I+K E V +++K D+ + K+ + ++M R + +R+QE+ IRE+ Sbjct: 490 --IRKQEEKVWRQEEKMHDQ-----EEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQ 542 Query: 2848 EQKHQSISEDISQYYIGPLRISSQQINYSSFDAPRIRTDEELEFLIAQRAKEKDVGIAKH 2907 E+ Q E +G Q+ +IR EE + +E+ I + Sbjct: 543 EEMMQEQEEK-----MGEQEEKMQEQEKMRRQEEKIREQEE-------KIREQKEKIREQ 590 Query: 2908 SVSIPWEREGSKRLDIPLNSKGQNIFFTELDTSQQKICQEQELLKQEDISM 2958 I WE+E R + + + + + ++K+C+++E +++++ M Sbjct: 591 EEKI-WEQEEKIREQEEMMQEQEEKMWEQ----EEKMCEQEEKMQEQEEKM 636 >gi|4503257 death-domain associated protein isoform a [Homo sapiens] Length = 740 Score = 52.8 bits (125), Expect = 1e-05 Identities = 62/280 (22%), Positives = 116/280 (41%), Gaps = 26/280 (9%) Query: 4052 QKSSEAGEKADGVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDIMHPE---DKGLKAK 4108 + S A + D V SK + K+++ ++K ++ ++ PE D G Sbjct: 363 ENRSLAMSRLDEVISK--YAMLQDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPS 420 Query: 4109 KALSQDLPLNTKEPGKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHE 4168 SQ P ++ + D E E+ E+ E EE+ +E+ +E+ D E ++G+ D E Sbjct: 421 GMASQGCPSASR--AETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDE 478 Query: 4169 VEEQQKADGVGIEQGKMDGDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQG-IIRP 4227 E++++ G DGDK+ L + + +L +R GE+ +G I+ P Sbjct: 479 EEDEEEEAAAG-----KDGDKSPMSS---LQISNEKNLEPGKQISRSSGEQQNKGRIVSP 530 Query: 4228 GILQPRHQKSSETGKKANGVPSEGDSASEVQKAKDYMQQKEEDESKQETVLFLHLPSESS 4287 +L S ++NG E + E + + E L L + SS Sbjct: 531 SLLSEEPLAPSSIDAESNGEQPEELTLEEESPVSQLFELEIE---------ALPLDTPSS 581 Query: 4288 LTCYELNTRKEGEEDLQGIIKSATLQLRQQKSFDAGKIAH 4327 + ++RK+ EE ++++ + SF+ G H Sbjct: 582 VETDISSSRKQSEEPFTTVLENGA-GMVSSTSFNGGVSPH 620 Score = 34.7 bits (78), Expect = 3.4 Identities = 33/144 (22%), Positives = 59/144 (40%), Gaps = 21/144 (14%) Query: 803 SHSASKQEKLPDEKETQNAEYIDKSCTFKKPQQCDRKEQEKEANSELTQGFRFSIHLKQK 862 S ++E+ +E+E ++E + ++ Q+ D +E E+E + G + + Q Sbjct: 443 SDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQI 502 Query: 863 PKYVKFQM-EQISSGSSKAPNKEQEVQPQTLSTQTILENSPCPMMDPFQVEKVKQSTDRP 921 + +QIS S + NK + V P LS + + +S Sbjct: 503 SNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPSS-------------------- 542 Query: 922 TDRESAGDPKNPLTMPENLPVGEL 945 D ES G+ LT+ E PV +L Sbjct: 543 IDAESNGEQPEELTLEEESPVSQL 566 >gi|215422388 death-domain associated protein isoform a [Homo sapiens] Length = 740 Score = 52.8 bits (125), Expect = 1e-05 Identities = 62/280 (22%), Positives = 116/280 (41%), Gaps = 26/280 (9%) Query: 4052 QKSSEAGEKADGVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDIMHPE---DKGLKAK 4108 + S A + D V SK + K+++ ++K ++ ++ PE D G Sbjct: 363 ENRSLAMSRLDEVISK--YAMLQDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPS 420 Query: 4109 KALSQDLPLNTKEPGKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHE 4168 SQ P ++ + D E E+ E+ E EE+ +E+ +E+ D E ++G+ D E Sbjct: 421 GMASQGCPSASR--AETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDE 478 Query: 4169 VEEQQKADGVGIEQGKMDGDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQG-IIRP 4227 E++++ G DGDK+ L + + +L +R GE+ +G I+ P Sbjct: 479 EEDEEEEAAAG-----KDGDKSPMSS---LQISNEKNLEPGKQISRSSGEQQNKGRIVSP 530 Query: 4228 GILQPRHQKSSETGKKANGVPSEGDSASEVQKAKDYMQQKEEDESKQETVLFLHLPSESS 4287 +L S ++NG E + E + + E L L + SS Sbjct: 531 SLLSEEPLAPSSIDAESNGEQPEELTLEEESPVSQLFELEIE---------ALPLDTPSS 581 Query: 4288 LTCYELNTRKEGEEDLQGIIKSATLQLRQQKSFDAGKIAH 4327 + ++RK+ EE ++++ + SF+ G H Sbjct: 582 VETDISSSRKQSEEPFTTVLENGA-GMVSSTSFNGGVSPH 620 Score = 34.7 bits (78), Expect = 3.4 Identities = 33/144 (22%), Positives = 59/144 (40%), Gaps = 21/144 (14%) Query: 803 SHSASKQEKLPDEKETQNAEYIDKSCTFKKPQQCDRKEQEKEANSELTQGFRFSIHLKQK 862 S ++E+ +E+E ++E + ++ Q+ D +E E+E + G + + Q Sbjct: 443 SDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQI 502 Query: 863 PKYVKFQM-EQISSGSSKAPNKEQEVQPQTLSTQTILENSPCPMMDPFQVEKVKQSTDRP 921 + +QIS S + NK + V P LS + + +S Sbjct: 503 SNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPSS-------------------- 542 Query: 922 TDRESAGDPKNPLTMPENLPVGEL 945 D ES G+ LT+ E PV +L Sbjct: 543 IDAESNGEQPEELTLEEESPVSQL 566 >gi|215422366 death-domain associated protein isoform b [Homo sapiens] Length = 752 Score = 52.8 bits (125), Expect = 1e-05 Identities = 62/280 (22%), Positives = 116/280 (41%), Gaps = 26/280 (9%) Query: 4052 QKSSEAGEKADGVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDIMHPE---DKGLKAK 4108 + S A + D V SK + K+++ ++K ++ ++ PE D G Sbjct: 375 ENRSLAMSRLDEVISK--YAMLQDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPS 432 Query: 4109 KALSQDLPLNTKEPGKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHE 4168 SQ P ++ + D E E+ E+ E EE+ +E+ +E+ D E ++G+ D E Sbjct: 433 GMASQGCPSASR--AETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDE 490 Query: 4169 VEEQQKADGVGIEQGKMDGDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQG-IIRP 4227 E++++ G DGDK+ L + + +L +R GE+ +G I+ P Sbjct: 491 EEDEEEEAAAG-----KDGDKSPMSS---LQISNEKNLEPGKQISRSSGEQQNKGRIVSP 542 Query: 4228 GILQPRHQKSSETGKKANGVPSEGDSASEVQKAKDYMQQKEEDESKQETVLFLHLPSESS 4287 +L S ++NG E + E + + E L L + SS Sbjct: 543 SLLSEEPLAPSSIDAESNGEQPEELTLEEESPVSQLFELEIE---------ALPLDTPSS 593 Query: 4288 LTCYELNTRKEGEEDLQGIIKSATLQLRQQKSFDAGKIAH 4327 + ++RK+ EE ++++ + SF+ G H Sbjct: 594 VETDISSSRKQSEEPFTTVLENGA-GMVSSTSFNGGVSPH 632 Score = 34.7 bits (78), Expect = 3.4 Identities = 33/144 (22%), Positives = 59/144 (40%), Gaps = 21/144 (14%) Query: 803 SHSASKQEKLPDEKETQNAEYIDKSCTFKKPQQCDRKEQEKEANSELTQGFRFSIHLKQK 862 S ++E+ +E+E ++E + ++ Q+ D +E E+E + G + + Q Sbjct: 455 SDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQI 514 Query: 863 PKYVKFQM-EQISSGSSKAPNKEQEVQPQTLSTQTILENSPCPMMDPFQVEKVKQSTDRP 921 + +QIS S + NK + V P LS + + +S Sbjct: 515 SNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPSS-------------------- 554 Query: 922 TDRESAGDPKNPLTMPENLPVGEL 945 D ES G+ LT+ E PV +L Sbjct: 555 IDAESNGEQPEELTLEEESPVSQL 578 >gi|34878904 synaptonemal complex protein 1 [Homo sapiens] Length = 976 Score = 52.0 bits (123), Expect = 2e-05 Identities = 90/463 (19%), Positives = 202/463 (43%), Gaps = 66/463 (14%) Query: 2761 IQQQKSFQLSKN----AVHRVLKAVYDSGYCVSSIKKLTEVKMEK-DKPKDRTCILPQPK 2815 + ++K Q+ ++ A H + +++ C S+++L + ++ +K +D+ IL Sbjct: 355 LTEEKETQMEESNKARAAHSFVVTEFETTVC--SLEELLRTEQQRLEKNEDQLKILTM-- 410 Query: 2816 LEKPLKEMQRSLSGCTDMSSILRKQEQDIREKEQKHQSISEDISQYYIGPLRISSQQINY 2875 E+Q+ S +M+ + +E ++ E ++ + E + Y + + Sbjct: 411 ------ELQKKSSELEEMTKLTNNKEVELEELKKV---LGEKETLLY--------ENKQF 453 Query: 2876 SSFDAPRIRTDEELEFLIAQRAKE-KDVGIAKHSVSIPWEREGSKRLDIPLNSKGQNIFF 2934 T++EL L+ R KE D+ I +++ + + D+ + + + Sbjct: 454 EKIAEELKGTEQELIGLLQAREKEVHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLKN 513 Query: 2935 TELDTSQQKICQEQELLKQEDISMTNLGSMACPIMEPLHLENTGKVTEEEDVYINRKISS 2994 TEL + K+ E + L QE MT L L+N ++ED+ N+K Sbjct: 514 TELTSHCNKLSLENKELTQETSDMT------------LELKN-----QQEDINNNKKQEE 556 Query: 2995 HVLGK-EGLKETDIFVGSK----GQKFLCTNSEVQHKVPAEQKEQVNPDHVPESILDSES 3049 +L + E L+ET+ + ++ ++ EV+ K+ K + N +++ + + + Sbjct: 557 RMLKQIENLQETETQLRNELEYVREELKQKRDEVKCKL---DKSEENCNNLRKQVENKNK 613 Query: 3050 FLSKDPLHLKQAVNTARKENVTISESFNENLWGKEQSKLDITLKSNRQKMDFSKKLRMKH 3109 ++ + Q N A K+ T +ES N++ + +KL++ L+S +QK K Sbjct: 614 YIEE-----LQQENKALKKKGT-AESKQLNVYEIKVNKLELELESAKQKFGEITDTYQKE 667 Query: 3110 LSNYYQNKENILESVLPCILHQLYIENPKKEGSAEEIMSSKV--LSPMVEKASHEVGIPV 3167 + + ++EN+LE V + + E K + ++ K+ + ++EK H+ + Sbjct: 668 IEDKKISEENLLEEVEKAKV--IADEAVKLQKEIDKRCQHKIAEMVALMEKHKHQYDKII 725 Query: 3168 DQPPCSEGIHLNIKGRKEHPQESTHEAFPASVSHSLMDVLQIK 3210 ++ G++ + KE Q S + +S+ ++L +K Sbjct: 726 EERDSELGLYKS----KEQEQSSLRASLEIELSNLKAELLSVK 764 Score = 38.9 bits (89), Expect = 0.18 Identities = 56/288 (19%), Positives = 125/288 (43%), Gaps = 47/288 (16%) Query: 3866 ALEVKQPSIFQELELNIKEKGGKIQEDKEV-EIWSKPFASISFLPYSKVGTIEGEEAMRI 3924 A ++K+ + E EL KE K+QE++++ E K + F G E + + Sbjct: 113 AEKIKKWKVSTEAELRQKES--KLQENRKIIEAQRKAIQELQF----------GNEKVSL 160 Query: 3925 KMRSSFSQPN--LQESSDTEKTAYEKCISDNISNSVKKALESILQKEQRQK--MEKIRAL 3980 K+ + ++E++ T + + + S +K + ++E+ ++ M+ + Sbjct: 161 KLEEGIQENKDLIKENNATRHLC--NLLKETCARSAEKTKKYEYEREETRQVYMDLNNNI 218 Query: 3981 KKMKSSISQ----------GIQLDIKEQEKRIEHIKGEPSVLLTNACASIPSPSHLQLDT 4030 +KM ++ + + +KE ++I+H++ E + + + L L Sbjct: 219 EKMITAFEELRVQAENSRLEMHFKLKEDYEKIQHLEQEYKKEINDKEKQVS----LLLIQ 274 Query: 4031 RREKAEYVTEITRYYLPELSHQKSSEAGEKADGVASKGDITIKVQKAKDYMQQKEDDEVK 4090 EK + ++T +L E S K ++ EK + +K K + KE +++K Sbjct: 275 ITEKENKMKDLT--FLLEESRDKVNQLEEKTKLQSEN----LKQSIEKQHHLTKELEDIK 328 Query: 4091 ISAKKDIMHPEDKGLKAKKALSQDLPLNTKEPGKMDQEAQEQGKEDRE 4138 +S ++ + +KAL +DL + TK ++ +E + Q +E + Sbjct: 329 VSLQRSV--------STQKALEEDLQIATKTICQLTEEKETQMEESNK 368 Score = 38.5 bits (88), Expect = 0.23 Identities = 148/736 (20%), Positives = 277/736 (37%), Gaps = 143/736 (19%) Query: 509 NKSPDTEKINYAGPLEETGISDITKKE--KEYDKENKR-LKNISPKMLPQLEQSFMVNTV 565 + P +K+N+ LE+ G SD +E K+ D EN L + K+ + E+ + Sbjct: 63 DSDPALQKVNFLPVLEQVGNSDCHYQEGLKDSDLENSEGLSRVYSKLYKEAEK---IKKW 119 Query: 566 QLKAPCLLVETNGKSKESLKDSITQAKGIGITEFHVLNSKKPFDLH--IPKHK------- 616 ++ L + K +E+ K I +A+ I E N K L I ++K Sbjct: 120 KVSTEAELRQKESKLQENRK--IIEAQRKAIQELQFGNEKVSLKLEEGIQENKDLIKENN 177 Query: 617 ------TSLEEAISKPMQKLVSSPEMESNNRMKIQEDLQS---------------SENSH 655 L+E ++ +K E E ++ DL + +ENS Sbjct: 178 ATRHLCNLLKETCARSAEK-TKKYEYEREETRQVYMDLNNNIEKMITAFEELRVQAENSR 236 Query: 656 LQLSNGEELPTSTPKTQRC---FPRENTQKQKDFLELVLELS-NVGLLISLGSKMHKSSE 711 L++ +L K Q + +E K+K L+++++ + L + +S + Sbjct: 237 LEMH--FKLKEDYEKIQHLEQEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRD 294 Query: 712 ELEAIKIQVNTESVNLKESKPLILNVTED-SDLRES------------EELECNTGSNIT 758 ++ ++ + +S NLK+S ++T++ D++ S E+L+ T I Sbjct: 295 KVNQLEEKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIAT-KTIC 353 Query: 759 NMHQDKET-------SDAFHS-------ATYTTISQLPDTETHSISK----AKADTLRII 800 + ++KET + A HS T ++ +L TE + K K T+ + Sbjct: 354 QLTEEKETQMEESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKILTMELQ 413 Query: 801 RLSHSASKQEKLPDEKETQNAEYIDKSCTFKKPQQCDRKEQEKEANSELTQGFRFSIHLK 860 + S + KL + KE + E + K K+ + K+ EK A EL + I L Sbjct: 414 KKSSELEEMTKLTNNKEVE-LEELKKVLGEKETLLYENKQFEKIA-EELKGTEQELIGLL 471 Query: 861 QKPKYVKFQMEQISSGSSKAPNKEQEVQPQTLSTQTILEN---------SPCPMMDPFQV 911 Q + ++ + + EQ + +T LEN S C + Sbjct: 472 QAREK---EVHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLKNTELTSHCNKLSLENK 528 Query: 912 EKVKQSTDRPTDRESAGDPKNPLTMPENLPVGELLIETTEYSVPFGGNLQKTTDSHIAEE 971 E ++++D + ++ + N N E +++ E NLQ+ T++ + E Sbjct: 529 ELTQETSDMTLELKNQQEDIN-----NNKKQEERMLKQIE-------NLQE-TETQLRNE 575 Query: 972 KEDVKRYLPAVALGSFNNHLLTLPYFKRQEIKKKLSETKSVLSVKYVIMKVKKPAISLMP 1031 E V+ L KR E+K KL +++ + ++K + Sbjct: 576 LEYVREELKQ----------------KRDEVKCKLDKSEENCN------NLRKQVENKNK 613 Query: 1032 YINICGTSNHRKKMGGNFEIIIKQILQDKIAAGMLLNVIYPPMSILPNTRMYSRLNAENH 1091 YI N K G E KQ+ +I L + + + + + Sbjct: 614 YIEELQQENKALKKKGTAE--SKQLNVYEIKVNKL------ELELESAKQKFGEITDTYQ 665 Query: 1092 SHI--KLVQEESQIEREEKYPYFINEGNESQNTLDAKLQDEVKGV-------KETLPKAV 1142 I K + EE+ +E EK +E + Q +D + Q ++ + K K + Sbjct: 666 KEIEDKKISEENLLEEVEKAKVIADEAVKLQKEIDKRCQHKIAEMVALMEKHKHQYDKII 725 Query: 1143 LHDSCNLGLDAHLEKE 1158 LGL E+E Sbjct: 726 EERDSELGLYKSKEQE 741 Score = 33.9 bits (76), Expect = 5.8 Identities = 44/164 (26%), Positives = 78/164 (47%), Gaps = 23/164 (14%) Query: 4457 KLKYTLSYLNDITGDSNRTK---YMAQIQKDKAN-ISEKSVMHPEYIAVKAEKSPLSHIL 4512 K K L IT N+ K ++ + +DK N + EK+ + E + EK H L Sbjct: 264 KEKQVSLLLIQITEKENKMKDLTFLLEESRDKVNQLEEKTKLQSENLKQSIEKQ---HHL 320 Query: 4513 KTKELQ-VNIS-QQGEKAQEGEVEIVVLLSKTCPFVTSSAFLELDSIKEEEGEPRITRSF 4570 TKEL+ + +S Q+ Q+ E + + +KT +T E ++ EE + R SF Sbjct: 321 -TKELEDIKVSLQRSVSTQKALEEDLQIATKTICQLTE----EKETQMEESNKARAAHSF 375 Query: 4571 MPHLEIQESLPSRQTAPTKPTESLVKKEKQLLPQKEDRVQTVSM 4614 + E + ++ S E L++ E+Q L + ED+++ ++M Sbjct: 376 VV-TEFETTVCS--------LEELLRTEQQRLEKNEDQLKILTM 410 Score = 33.5 bits (75), Expect = 7.6 Identities = 76/416 (18%), Positives = 174/416 (41%), Gaps = 54/416 (12%) Query: 3763 KKLEKMTQEDESNLNVVQNKLCASILSPPHLEWNPRIKEVYMRGITRFCLSSSTQQELSD 3822 +K++ + QE + +N + ++ ++ KE M+ +T F L S + +++ Sbjct: 248 EKIQHLEQEYKKEINDKEKQVSLLLIQITE-------KENKMKDLT-FLLEES-RDKVNQ 298 Query: 3823 TMEKCEQPIDDSLSSIEKAKHMPQKDKDRVEKALEKIMHSKRIA---LEVKQPSIFQELE 3879 EK + ++ SIEK H+ ++ +D ++ +L++ + +++ L++ +I Q E Sbjct: 299 LEEKTKLQSENLKQSIEKQHHLTKELED-IKVSLQRSVSTQKALEEDLQIATKTICQLTE 357 Query: 3880 LNIKEKGGKIQEDKEVEIWSKPFASISFLPYSKVGTIEG-EEAMRIKMRSSFSQPNLQES 3938 +++ ++E +K A+ SF+ T+ EE +R + Q L+++ Sbjct: 358 ----------EKETQMEESNKARAAHSFVVTEFETTVCSLEELLRTE------QQRLEKN 401 Query: 3939 SDTEKTAYEKCISDNISNSVKKALESILQKEQRQKMEKIRALKKMKSSISQGIQLDIKEQ 3998 D K + LE + + +++E + LKK+ + + + K+ Sbjct: 402 EDQLKILTMEL------QKKSSELEEMTKLTNNKEVE-LEELKKVLGE-KETLLYENKQF 453 Query: 3999 EKRIEHIKGEPSVLLTNACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEAG 4058 EK E +KG L+ A L++ +T +YY E+ K+ Sbjct: 454 EKIAEELKGTEQELIGLLQAREKEVHDLEIQLTA-----ITTSEQYYSKEVKDLKTELEN 508 Query: 4059 EKADGVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPLN 4118 EK + K+ Q+ D +++ +++ ++ K + ++ L Q L Sbjct: 509 EKLKNTELTSHCNKLSLENKELTQETSDMTLELKNQQEDINNNKK--QEERMLKQIENL- 565 Query: 4119 TKEPGKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQK 4174 QE + Q + + E + + +R + K+D+ ++ + +VE + K Sbjct: 566 --------QETETQLRNELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNK 613 Score = 33.1 bits (74), Expect = 9.9 Identities = 59/275 (21%), Positives = 103/275 (37%), Gaps = 31/275 (11%) Query: 602 LNSKKPFDLHIPKHKTSLEEAISKPMQKLVSSPEMESNNRMKIQEDLQSSENSHLQLSNG 661 + +KPF L +P +S + + KP S +S N K ED + LS Sbjct: 1 MEKQKPFALFVPPRSSSSQVSAVKPQTLGGDSTFFKSFN--KCTEDDFEFPFAKTNLSKN 58 Query: 662 EELPTSTPKTQRCFPRENTQKQKDFLELVLELSNVGLLISLGSKMH--KSSEELEAIKIQ 719 E S P Q+ +FL ++ ++ N G K ++SE L + + Sbjct: 59 GENIDSDPALQKV----------NFLPVLEQVGNSDCHYQEGLKDSDLENSEGLSRVYSK 108 Query: 720 VNTESVNLKESKPLILNVTEDSDLRESEELECNTGSNITNMHQDKETSDAFHSATYTTIS 779 + E+ +K+ K V+ +++LR+ E + I + F + + Sbjct: 109 LYKEAEKIKKWK-----VSTEAELRQKES-KLQENRKIIEAQRKAIQELQFGNEKVSLKL 162 Query: 780 QLPDTETHSISKAKADTLRIIRL-----SHSASKQEKLPDEKETQNAEYIDKSCTFKKPQ 834 + E + K T + L + SA K +K E+E Y+D + +K Sbjct: 163 EEGIQENKDLIKENNATRHLCNLLKETCARSAEKTKKYEYEREETRQVYMDLNNNIEKMI 222 Query: 835 QCDRKEQEKEANSELTQGFRFSIHLKQKPKYVKFQ 869 + + + NS R +H K K Y K Q Sbjct: 223 TAFEELRVQAENS------RLEMHFKLKEDYEKIQ 251 >gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo sapiens] Length = 1940 Score = 51.6 bits (122), Expect = 3e-05 Identities = 99/457 (21%), Positives = 198/457 (43%), Gaps = 70/457 (15%) Query: 3756 KEPQRSNKKLEKMTQE----DESNLNVVQNKLCASILSPPHLEWNPRIKEVYMRGITRFC 3811 KE + K++ +T+E DE+ + + K ++E + + + Sbjct: 967 KEKHATENKVKNLTEELSGLDETIAKLTREKKA--------------LQEAHQQALDDLQ 1012 Query: 3812 LSSSTQQELSDTMEKCEQPIDDSLSSIEKAKHMPQKDKDRVEKALE---KIMHSKRIALE 3868 L+ T K EQ ++D SS+E+ K + + D +R ++ LE K+ + LE Sbjct: 1013 AEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKL-RVDLERNKRKLEGDLKLAQESILDLE 1071 Query: 3869 VKQPSIFQELELNIKEKG-------GKIQEDKEVEI-WSKPFASISFLPYSKVGTIEGEE 3920 + Q+L+ +K+K K+++++ + + + K + IE E Sbjct: 1072 NDK----QQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAER 1127 Query: 3921 AMRI---KMRSSFSQPNLQESSDTEKTAYEKCISDNISNSVKKA----LESILQKEQRQK 3973 A R K RS +++ L+E S+ + A + N ++A L L++ Q Sbjct: 1128 ATRAKTEKQRSDYAR-ELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQH 1186 Query: 3974 MEKIRAL-KKMKSSISQ-GIQLD-IKEQEKRIEHIKGEPSVLLTNACASIPSPSHLQ--- 4027 + AL KK S+++ G Q+D ++ ++++E K E + + + +S+ S S + Sbjct: 1187 EAMVAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANL 1246 Query: 4028 ------LDTRREKAEYVTEITRYYLPELSHQKS---SEAGEKADGVASKGDITIKVQKAK 4078 L+ + +A E + L EL+ QKS +EAGE + + K I ++ ++K Sbjct: 1247 EKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSK 1306 Query: 4079 DYMQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPLNTKEPGKMDQEAQEQGKEDRE 4138 Q + +E+K +++ KAK AL+ L + + + +EQ +E++E Sbjct: 1307 QAFTQ-QTEELKRQLEEE--------NKAKNALAHALQSSRHDCDLL----REQYEEEQE 1353 Query: 4139 GEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKA 4175 G+ + + A E K + EE ++A Sbjct: 1354 GKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEA 1390 Score = 35.4 bits (80), Expect = 2.0 Identities = 89/465 (19%), Positives = 181/465 (38%), Gaps = 67/465 (14%) Query: 423 LKAKKTPTSQVFQITVCHTLKNRNELGCKNNTEKKELHE-----RKDISDIALHLISVSK 477 +KAK +++ ++T ++ E+ + +K++L + +KDI D+ L L V K Sbjct: 910 IKAKFQLEAKIKEVT--ERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEK 967 Query: 478 LILPYVKNYSRKQLVKVMPGLIKCGHFLQKQNKSPDTEKINYAGPLEETGISDITKKEKE 537 + K L + + GL + L ++ K+ L+E + + E Sbjct: 968 E--KHATENKVKNLTEELSGLDETIAKLTREKKA-----------LQEAHQQALDDLQAE 1014 Query: 538 YDKENK--RLKNISPKMLPQLEQSFMVNTVQLKAPCLLVETNGKSKESLKDSITQAKGIG 595 DK N + K+ + + LE S +E K + L+ + + +G Sbjct: 1015 EDKVNSLNKTKSKLEQQVEDLESS--------------LEQEKKLRVDLERNKRKLEGD- 1059 Query: 596 ITEFHVLNSKKPFDLHIPKHKTSLEEAISKP---MQKLVSSPEMESNNRMKIQEDLQSSE 652 L + L + K L+E + K +L S E E ++ Q+ ++ + Sbjct: 1060 ------LKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQ 1113 Query: 653 NSHLQLSNGEELPTSTPKTQRCFPRENTQKQK-----DFLELVLELSNVGLLISLGSKMH 707 +L E +T R T+KQ+ + EL L G + S +++ Sbjct: 1114 ARIEELEEEIEAERAT--------RAKTEKQRSDYARELEELSERLEEAGGVTSTQIELN 1165 Query: 708 KSSEELEAIKIQVNTESVNLKESKPLILNVTEDSDLRESEELECNTGSNITNMHQDKETS 767 K E E +K++ + E L+ + + +D G I N+ + K+ Sbjct: 1166 KK-REAEFLKLRRDLEEATLQHEAMVAALRKKHADS------VAELGEQIDNLQRVKQKL 1218 Query: 768 DAFHSATYTTISQLPDTETHSISKAKADTLRIIRLSHSASKQEKLPDEKETQNAEYIDKS 827 + S I L + S+SK+KA+ +I R + + +E+ ++ + Sbjct: 1219 EKEKSEFKLEIDDL-SSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQ 1277 Query: 828 CTFKKPQQCDRKEQEKEANSELTQGFRFSIHLKQKPKYVKFQMEQ 872 + + + + Q +E S ++Q R Q+ + +K Q+E+ Sbjct: 1278 KSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEE 1322 >gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] Length = 1976 Score = 51.6 bits (122), Expect = 3e-05 Identities = 114/556 (20%), Positives = 235/556 (42%), Gaps = 94/556 (16%) Query: 3812 LSSSTQQELSDTMEKCEQPIDDSLSSIEKAKHMPQKDKDRVEKALEKIMHSKRIALEVKQ 3871 L + +QE+++ + E+ + + I+ M Q+ +E+ E++ +KR +++ Sbjct: 1168 LRTKREQEVAELKKALEEETKNHEAQIQD---MRQRHATALEELSEQLEQAKRFKANLEK 1224 Query: 3872 PSIFQELELNIKEKGGKIQEDKEVEIWS-----KPFASISFLPYSKVGTIEGEEAMRIKM 3926 Q LE + KE +++ ++V+ S K A + L ++KV E R+++ Sbjct: 1225 NK--QGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQEL-HAKVS-----EGDRLRV 1276 Query: 3927 RSSFSQPNLQESSDTEKTAYEKCISDNISNSVKKA-LES-------ILQKEQRQKM---E 3975 + LQ D T E+ I + A LES +LQ+E RQK+ Sbjct: 1277 ELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSS 1336 Query: 3976 KIRALKKMKSSISQGIQLDIKEQEKRIEHIKGEPSVLLTNACASIPSPSHLQLDTRREKA 4035 +IR L++ K+S +Q +E+E+ ++++ + L + DT+++ Sbjct: 1337 RIRQLEEEKNS----LQEQQEEEEEARKNLEKQVLALQSQLA-----------DTKKKVD 1381 Query: 4036 EYVTEITRYYLPELSHQKSSEAGEKADGVASKGDITIKVQKAKDYMQQKEDD-EVKISAK 4094 + + I L E + +A + + K K++K K+ +QQ+ DD V + + Sbjct: 1382 DDLGTIES--LEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQ 1439 Query: 4095 KDI-MHPEDKGLKAKKALSQDLPLNTKEPGKMDQ-EAQEQGKEDR---------EGEEQG 4143 + + + E K K + L+++ ++ + + D+ EA+ + KE + E E Sbjct: 1440 RQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAK 1499 Query: 4144 KEDRRGAGQEKVDRED-----KEQGKMDHEVEEQQKADGVGIEQGKMDGDKNEQERV--- 4195 +E R Q + D ED + GK HE+E+ ++A +E+ + ++ E E Sbjct: 1500 EEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATE 1559 Query: 4196 -----LFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSSETGKKANGVPSE 4250 L + + + + L TR E E+++ ++ + + + E ++A V S+ Sbjct: 1560 DAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASK 1619 Query: 4251 -------GDSASEVQKA------------------KDYMQQKEEDESKQETVLFLHLPSE 4285 D ++++ A KDY ++ EE + ++ + SE Sbjct: 1620 KKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESE 1679 Query: 4286 SSLTCYELNTRKEGEE 4301 L E + EE Sbjct: 1680 KKLKSLEAEILQLQEE 1695 Score = 41.2 bits (95), Expect = 0.036 Identities = 72/333 (21%), Positives = 134/333 (40%), Gaps = 41/333 (12%) Query: 539 DKENKRLKNISPKMLPQLEQSFMVNTVQLKAPCLLVETNGKSKESLKDSITQAKGIGITE 598 D++N+ K + K + +LE + K L V + K + LKD Q + Sbjct: 1584 DEQNEEKKRLLIKQVRELEAEL---EDERKQRALAVASKKKMEIDLKDLEAQIEAANKAR 1640 Query: 599 FHVLNSKKPFDLHIPKHKTSLEEAISKPMQKLVSSPEMESNNRMKIQEDLQSSENSHLQL 658 V+ + + ++ LEEA + + S E E + L+S E LQL Sbjct: 1641 DEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESE--------KKLKSLEAEILQL 1692 Query: 659 SNGEELPTSTPKTQRCFPRENTQKQKDFL--ELVLELSNVGLLIS----LGSKMHKSSEE 712 EEL +S R + ++++D L E+ S L+ L +++ + EE Sbjct: 1693 Q--EELASSER------ARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEE 1744 Query: 713 LEAIKIQVNTESVNLKESKPLILNVTEDSDL---RESEELECNTGSNITNMHQD-----K 764 LE + Q N E +N + K + T +++L R + + N + +++ + Sbjct: 1745 LE--EEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQ 1802 Query: 765 ETSDAFHSATYTTISQLP------DTETHSISKAKADTLRIIRLSHSASKQEKLPDEKET 818 E A S TIS L + + +K +A +++R + K+ + E E Sbjct: 1803 ELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDER 1862 Query: 819 QNAEYIDKSCTFKKPQQCDRKEQEKEANSELTQ 851 ++A+ + + K Q +EA E T+ Sbjct: 1863 RHADQYKEQMEKANARMKQLKRQLEEAEEEATR 1895 Score = 35.4 bits (80), Expect = 2.0 Identities = 99/594 (16%), Positives = 223/594 (37%), Gaps = 69/594 (11%) Query: 4072 IKVQKAKDYMQQKEDDEVKISAKKDIMHPE--------DKGLKAKKALSQDLPLNTKEPG 4123 ++V + ++ +Q K+++ +K+ K+ + E + L+ K L++ L T+ Sbjct: 845 LQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFA 904 Query: 4124 KMDQEAQEQGKEDREGEE--QGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADGVGIE 4181 + ++ + +E EE E R +E+ E+ KM +++ ++ Sbjct: 905 EAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEE------- 957 Query: 4182 QGKMDGDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSSETG 4241 ++D ++ ++++ + + + + + + +++ + I +++ R +E Sbjct: 958 --QLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDR---IAECS 1012 Query: 4242 KKANGVPSEGDSASEVQKAKDYMQQKEEDESKQETVLFLHLPSESSLTCYELNTRKEGEE 4301 + + + ++++ ++ M E+ K+E L E ++ Sbjct: 1013 SQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIA 1072 Query: 4302 DLQGIIKSATLQLRQQKSFDAGKIAHTKSFGVDSSNDVKTVQEYKPQ----------KEV 4351 +LQ I LQL +++ G +A + +N +K V+E + Q ++ Sbjct: 1073 ELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKA 1132 Query: 4352 DRGKTVSVDYIMQPEGTIFEAEQLSLPHTLNIPGSSGSKTREVLTNIKEKLRHVQERKSE 4411 R K + E EA + L TL+ + + + E + ++E Sbjct: 1133 SRNKAEKQKRDLSEE---LEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKN 1189 Query: 4412 LDVFLTIPSLSHCKLDKRTAGKKEEQGVTRSFLPPSWHMESSDTGKLKYTLSYLNDITGD 4471 + + H + + + E+ ++ L + +D +L + L + + Sbjct: 1190 HEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAE 1249 Query: 4472 S--NRTKYMAQIQKDKANISEKSVMHPEY----------------IAVKAEKSPLSHILK 4513 S R K AQ+Q+ A +SE + E + +AEK + Sbjct: 1250 SEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKD 1309 Query: 4514 TKELQVNISQQGEKAQEGEVEIVVLLSKTCPFVTSSAFLELDSIKEEEGEPRITRSFMPH 4573 L+ + E QE + + L S+ E +S++E++ E R + Sbjct: 1310 AASLESQLQDTQELLQEETRQKLNLSSRIRQLEE-----EKNSLQEQQEEEEEARK---N 1361 Query: 4574 LEIQESLPSRQTAPTK--------PTESLVKKEKQLLPQKEDRVQTVSMHGLMH 4619 LE Q Q A TK ESL + +K+LL E Q + L + Sbjct: 1362 LEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAY 1415 Score = 33.5 bits (75), Expect = 7.6 Identities = 72/398 (18%), Positives = 154/398 (38%), Gaps = 66/398 (16%) Query: 529 SDITKKEKEYDKENKRLKNISPKMLPQLEQSFMV----NTVQLKAPCLLVET-------- 576 S++ KK+K++D+ K+IS + + +++ T L L E Sbjct: 1444 SNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFE 1503 Query: 577 --NGKSKESLKDSITQAKGIGITEFHVLNSKKPFDLHIPKHKTSLEEAISKPMQKLVSSP 634 N + + ++D ++ +G + SK+ + + + +T LEE Sbjct: 1504 RQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEE------------- 1550 Query: 635 EMESNNRMKIQEDLQSSENSHLQLS-NGEELPTSTPKTQRCFPRENTQKQKDFLELVLEL 693 ++++LQ++E++ L+L N + + + + +N +K++ ++ V EL Sbjct: 1551 ---------LEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVREL 1601 Query: 694 --------SNVGLLISLGSKMHKSSEELEA-IKIQVNTESVNLKESKPLILNVTEDSDLR 744 L ++ KM ++LEA I+ +K+ + L + + Sbjct: 1602 EAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKD----- 1656 Query: 745 ESEELECNTGSNITNMHQDKETSDAFHSATYTTISQLPDTETHSISKAKADTLR---IIR 801 ELE S Q KE+ S + + + ++ A+ R Sbjct: 1657 YQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADE 1716 Query: 802 LSHSASKQEKLPDEKETQNAEYIDKSCTFKKPQQCDRKEQEKEANSELTQGFRFSIHLKQ 861 +++SAS + L DEK A + Q + + +E+++N EL L+ Sbjct: 1717 ITNSASGKSALLDEKRRLEA----------RIAQLEEELEEEQSNMELLNDRFRKTTLQV 1766 Query: 862 KPKYVKFQMEQISSGSSKAPNKEQEVQPQTLSTQTILE 899 + E+ S + K+ N Q+++ Q + L+ Sbjct: 1767 DTLNAELAAER--SAAQKSDNARQQLERQNKELKAKLQ 1802 >gi|38569484 kinesin family member 21A [Homo sapiens] Length = 1661 Score = 51.2 bits (121), Expect = 4e-05 Identities = 69/324 (21%), Positives = 138/324 (42%), Gaps = 20/324 (6%) Query: 3964 SILQKEQRQKMEKIRALKKMKSSISQGIQLDIKEQEKRIEHIKGEPSVLLTNACASIPSP 4023 ++LQ E +I+A+++ ++ I + +Q + GE + ++N S Sbjct: 426 AMLQTENNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGEGNEEISNMIHSYIKE 485 Query: 4024 SHLQLDTRREKAEYVTEITRYYLPELSHQKSSEAGEK--ADGVASKGDITIKV----QKA 4077 L + ++E V E R L + + +G + + S TI++ +K Sbjct: 486 IE-DLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEIIDLAKKD 544 Query: 4078 KDYMQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPLNTKEPGKMD-QEAQE-QGKE 4135 + +++KE + K A K+ D+ K +K +S+ +E +++ +E+QE E Sbjct: 545 LEKLKRKEKRKKKSVAGKEDNTDTDQEKKEEKGVSE------RENNELEVEESQEVSDHE 598 Query: 4136 DREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADGVGIEQGKMDGDKNEQERV 4195 D E EE+ +ED G+ + + + K +++ + + I+Q +D +N Q+R+ Sbjct: 599 DEEEEEEEEEDDIDGGESSDESDSESDEKANYQADLANITCEIAIKQKLIDELENSQKRL 658 Query: 4196 LFL---YLPSNSSLTHYILDTRIEGEEDQQ--GIIRPGILQPRHQKSSETGKKANGVPSE 4250 L Y L H I DT++E ++ Q G + + + SE KK + E Sbjct: 659 QTLKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEYEKKLQAMNKE 718 Query: 4251 GDSASEVQKAKDYMQQKEEDESKQ 4274 QK + + + KQ Sbjct: 719 LQRLQAAQKEHARLLKNQSQYEKQ 742 >gi|41322923 plectin 1 isoform 11 [Homo sapiens] Length = 4547 Score = 51.2 bits (121), Expect = 4e-05 Identities = 93/531 (17%), Positives = 204/531 (38%), Gaps = 73/531 (13%) Query: 3817 QQELSDTMEKCEQPIDDSLSSIEKAKHMPQKDKDRVEKALEKIMHS------KRIALEVK 3870 Q++L++ + + L + ++ + +E+ L ++ KR LE + Sbjct: 1697 QRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAE 1756 Query: 3871 QPSIFQELELNIKEKGGKIQEDKEVEIWSKPFASISFLPYSKVGTIEGEEAMRIK----- 3925 + E+E+ + K +E + SK + ++ EEA R++ Sbjct: 1757 LAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELA----EEAARLRALAEE 1812 Query: 3926 ---MRSSFSQPNLQESSDTEKTAYEKCISDNISNSVKKALESILQKEQRQKMEKIRALKK 3982 R + ++ ++ E+ EK + + +K E L KE+ + E++R L + Sbjct: 1813 AKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIAL-KEKEAENERLRRLAE 1871 Query: 3983 MKSSISQGIQLDIKEQEKRIEHIKGEPSVLLTNACASIPSPSHLQLDTRREKAEYVTEIT 4042 D Q +R+E + + A + S +L+ ++ E Sbjct: 1872 -----------DEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQR 1920 Query: 4043 RYYLPELSHQKSSEAGEKADGVASKGDITIKVQK----AKDYMQQKEDDEVKISAKKDIM 4098 R E+ K+S EKA A K ++ +++ + A+D ++ KE E++ + ++ + Sbjct: 1921 RQVEEEILALKASF--EKA--AAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLA 1976 Query: 4099 HPEDKGLKAKKALSQDLPLNTKEPGKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDRE 4158 E++ + + Q +E + + A E+ + + E+ + R A QE + Sbjct: 1977 AEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQL 2036 Query: 4159 DKEQGKMDHEVEEQQKADGVGIEQGKMDGDKNEQERVLFLYLPSNSSLTHYILDTRIEGE 4218 Q ++ ++KA ++Q + + + Q+ +LD ++ GE Sbjct: 2037 QLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQE-------------QSVLD-QLRGE 2082 Query: 4219 EDQQGIIRPGILQPRHQKSSETGKKANGVPSEGDSASEVQKAKDYMQQKEEDESKQETVL 4278 +E ++A E +E + A+ Q +E + KQ Sbjct: 2083 -------------------AEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEE 2123 Query: 4279 FLHLPSESSLTCYELNTRKEGEEDLQGIIKSATLQLRQQKSFDAGKIAHTK 4329 +++ +L RKE E++ ++ LRQ+++ DA H K Sbjct: 2124 QAQARAQAQAAAEKL--RKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK 2172 Score = 46.2 bits (108), Expect = 0.001 Identities = 90/464 (19%), Positives = 177/464 (38%), Gaps = 54/464 (11%) Query: 3840 KAKHMPQKDKDRV----EKALEKIMHSKRIALEVKQPSIFQELELNIKEKGGKIQEDKEV 3895 +AK + Q+ ++ V E A++ + I E++Q E E+ K + + E + Sbjct: 1389 EAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRL 1448 Query: 3896 EIWSKPFASISFLPYSKV--GTIEGE-EAMRIKMRSSFSQPNLQESSDTEKTAYEKCISD 3952 I + L ++ G EGE +A+R + + +Q Q + E+ + Sbjct: 1449 RIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKR-QAQEEAERLRRQVQDES 1507 Query: 3953 NISNSVKKALESILQKEQRQKMEKIRALKKMKSSISQGIQLDIKEQEKRIEHIKGEPSVL 4012 + L S ++ E EK RAL+ ++ ++L +E E+R+ + E + Sbjct: 1508 QRKRQAEVELASRVKAEAEAAREKQRALQALEE-----LRLQAEEAERRLRQAEVERARQ 1562 Query: 4013 LTNACASIPSPSHLQLDTRREKAEYVTEITRYYLPELSHQKSSEAGEKADGVASKGDITI 4072 + A L+T + AE + R E + Q E+ VA + Sbjct: 1563 VQVA-----------LETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQ-----L 1606 Query: 4073 KVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAKKAL---------SQDLPLNTKEPG 4123 + + + QQ E + + A++++ E LKA +AL +Q L E Sbjct: 1607 REEAERRAQQQAEAERAREEAEREL---ERWQLKANEALRLRLQAEEVAQQKSLAQAEAE 1663 Query: 4124 KMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADGV--GIE 4181 K +EA+ + + + EEQ R A QE + +G + +Q+ + E Sbjct: 1664 KQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETE 1723 Query: 4182 QGKMDGDKNEQERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSSETG 4241 QG+ E+E + ++ L+ + + ++ + + S + Sbjct: 1724 QGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSE 1783 Query: 4242 KKANGVPSEGDSASEV-----------QKAKDYMQQKEEDESKQ 4274 K + +E E+ ++AK Q EED ++Q Sbjct: 1784 KSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQ 1827 Score = 38.1 bits (87), Expect = 0.31 Identities = 75/372 (20%), Positives = 161/372 (43%), Gaps = 36/372 (9%) Query: 3815 STQQELSDTMEKCEQPIDD----SLSSIEKAKHMPQKDKDRV------EKALEKIMHSKR 3864 +TQ+ L + EK +Q ++ S+++ E A+ ++D EK L++ M + + Sbjct: 2261 NTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQ 2320 Query: 3865 IALEVK-QPSIFQELELNIKEKGGKIQEDKEVEIWSKPFASISFLPYSKVGTIEGEEAMR 3923 A +K + + Q+ + +E+ ++QEDKE + F T+E E + Sbjct: 2321 EATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQR-----TLEAERQRQ 2375 Query: 3924 IKMRSSFSQPNLQESSDTEKTAYEKCISDNISNSVKKALESILQKEQRQKMEKIRALKKM 3983 ++M + + L+ + + A ++ + +K E I +K R ++ + Sbjct: 2376 LEMSAEAERLKLRVAEMSRAQAR----AEEDAQRFRKQAEEIGEKLHRTELAT-----QE 2426 Query: 3984 KSSISQGIQLDIKEQEKRIEHIKGEPSVLLTNACASIPSPSHLQLDTRREKAEYVTEITR 4043 K ++ Q +++ ++ + E ++ E L + + L L + E+ + V + Sbjct: 2427 KVTLVQTLEIQRQQSDHDAERLR-EAIAELEREKEKLQQEAKL-LQLKSEEMQTVQQ--E 2482 Query: 4044 YYLPELSHQKSSEAGEKADGVASKGDITIKVQKAKDYMQQKEDDEVKISAKKDIMHPEDK 4103 L E + S EK D + + + I+ +KAK ++Q DEV AK + E + Sbjct: 2483 QLLQETQALQQSFLSEK-DSLLQR-ERFIEQEKAK--LEQLFQDEV---AKAQQLREEQQ 2535 Query: 4104 GLKAKKALSQDLPLNTKEPGKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKVDREDKEQG 4163 + + + + + E + Q E+G ++ E Q E +R +E + E++ Sbjct: 2536 RQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLR 2595 Query: 4164 KMDHEVEEQQKA 4175 + +EEQ +A Sbjct: 2596 EQLQLLEEQHRA 2607 Score = 36.6 bits (83), Expect = 0.89 Identities = 87/488 (17%), Positives = 188/488 (38%), Gaps = 97/488 (19%) Query: 3856 LEKIMHSKRIALEVKQPSIFQELELNIKEKGGKIQEDKEVEIWSKPFASISFLPYSKVGT 3915 LE+ + + +A+ + + + + + + + ++E+E W Sbjct: 1592 LERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQ---------------- 1635 Query: 3916 IEGEEAMRIKMRS-------SFSQPNLQ-ESSDTEKTAYEKCISDNISNSVKKALESILQ 3967 ++ EA+R+++++ S +Q + + + E+ A + ++ + ++ E L+ Sbjct: 1636 LKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELE 1695 Query: 3968 KEQR-------QKMEKIRALKKMKSSISQGIQLDIKEQEKRIEHIKGEPSVLLTNACASI 4020 K+++ Q++ + L ++++ QG EQ++++ ++ E + L A A+ Sbjct: 1696 KQRQLAEGTAQQRLAAEQELIRLRAETEQG------EQQRQL--LEEELARLQREAAAAT 1747 Query: 4021 PSPSHLQLDTRREKAEY---------VTEITRYYLPELSHQKSSEAGEKADGVASKGDIT 4071 L+ + + +AE E +R + + +EAG + + Sbjct: 1748 QKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLR 1807 Query: 4072 IKVQKAKDYMQQKEDDEVKISAKKDIMHPEDKGLKAKKALSQDLPLNTKEPGKMDQEAQE 4131 ++AK Q E+D + A+ A++ L++ L E ++ EA+ Sbjct: 1808 ALAEEAKRQRQLAEEDAARQRAE------------AERVLAEKLAA-IGEATRLKTEAEI 1854 Query: 4132 QGKEDREGEEQGKEDRRGAGQEKVDREDKEQGKMDHEVEEQQKADGVGIEQGKMDGDKNE 4191 KE E + + RR A E R E+ H KAD Sbjct: 1855 ALKEK---EAENERLRRLAEDEAFQRRRLEEQAAQH------KAD--------------I 1891 Query: 4192 QERVLFLYLPSNSSLTHYILDTRIEGEEDQQGIIRPGILQPRHQKSSETGKKANGVPSEG 4251 +ER+ L S+S L E Q+G++ + Q R + KA+ + Sbjct: 1892 EERLAQLRKASDSEL------------ERQKGLVEDTLRQRRQVEEEILALKASFEKAAA 1939 Query: 4252 DSASEVQKAKDYMQQKEEDESKQETVLFLHLPSESSLTCYELNTRKEGEEDLQGIIKSAT 4311 A E++ ++ ED + + L + L E R+E EE +Q + + Sbjct: 1940 GKA-ELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEE 1998 Query: 4312 LQLRQQKS 4319 RQ+K+ Sbjct: 1999 EAARQRKA 2006 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.311 0.127 0.355 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 267,564,723 Number of Sequences: 37866 Number of extensions: 12801483 Number of successful extensions: 45953 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 75 Number of HSP's successfully gapped in prelim test: 685 Number of HSP's that attempted gapping in prelim test: 36334 Number of HSP's gapped (non-prelim): 7478 length of query: 6929 length of database: 18,247,518 effective HSP length: 126 effective length of query: 6803 effective length of database: 13,476,402 effective search space: 91679962806 effective search space used: 91679962806 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 74 (33.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.