Guide to the Human Genome
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Search of human proteins with 239755460

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239755460 PREDICTED: similar to mucin, partial [Homo
sapiens]
         (1064 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239755460 PREDICTED: similar to mucin, partial [Homo sapiens]     2298   0.0  
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]      578   e-165
gi|161019170 mucin 5AC [Homo sapiens]                                 546   e-155
gi|116284392 mucin 2 precursor [Homo sapiens]                         537   e-152
gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]             536   e-152
gi|169202626 PREDICTED: similar to mucin 5, partial [Homo sapiens]    277   3e-74
gi|89191868 von Willebrand factor preproprotein [Homo sapiens]        210   7e-54
gi|239755545 PREDICTED: otogelin isoform 1 [Homo sapiens]             165   2e-40
gi|239755543 PREDICTED: otogelin isoform 2 [Homo sapiens]             165   2e-40
gi|239749989 PREDICTED: otogelin isoform 2 [Homo sapiens]             165   2e-40
gi|239749987 PREDICTED: otogelin isoform 1 [Homo sapiens]             165   2e-40
gi|239744300 PREDICTED: otogelin isoform 2 [Homo sapiens]             165   2e-40
gi|239744298 PREDICTED: otogelin isoform 1 [Homo sapiens]             165   2e-40
gi|16554449 zonadhesin isoform 3 [Homo sapiens]                       129   1e-29
gi|27881494 zonadhesin isoform 6 [Homo sapiens]                       129   1e-29
gi|134031945 SCO-spondin [Homo sapiens]                               127   4e-29
gi|239755901 PREDICTED: chromosome 12 open reading frame 64 [Hom...   114   4e-25
gi|239750386 PREDICTED: chromosome 12 open reading frame 64 [Hom...   114   5e-25
gi|239744688 PREDICTED: hypothetical protein LOC283310 [Homo sap...   114   6e-25
gi|239757286 PREDICTED: similar to Fc fragment of IgG binding pr...   108   3e-23
gi|239751787 PREDICTED: hypothetical protein XP_002348012 [Homo ...   108   3e-23
gi|154146262 Fc fragment of IgG binding protein [Homo sapiens]        108   3e-23
gi|239757282 PREDICTED: similar to Fc fragment of IgG binding pr...   101   4e-21
gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens]   100   7e-21
gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo ...    90   1e-17
gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo ...    90   1e-17
gi|151301154 mucin 6, gastric [Homo sapiens]                           83   2e-15
gi|239755778 PREDICTED: mucin 19, oligomeric [Homo sapiens]            73   1e-12
gi|239750280 PREDICTED: mucin 19, oligomeric [Homo sapiens]            73   1e-12
gi|239744589 PREDICTED: mucin 19 [Homo sapiens]                        73   1e-12

>gi|239755460 PREDICTED: similar to mucin, partial [Homo sapiens]
          Length = 1064

 Score = 2298 bits (5954), Expect = 0.0
 Identities = 1064/1064 (100%), Positives = 1064/1064 (100%)

Query: 1    HNLCSYNQHNLWSWNYSQPCSHRQHNLCSYNQNNLCLYSQHNLCPVPTTSTTSAPTTSTT 60
            HNLCSYNQHNLWSWNYSQPCSHRQHNLCSYNQNNLCLYSQHNLCPVPTTSTTSAPTTSTT
Sbjct: 1    HNLCSYNQHNLWSWNYSQPCSHRQHNLCSYNQNNLCLYSQHNLCPVPTTSTTSAPTTSTT 60

Query: 61   SGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDCHPLCAWTKWFDVDFPSPGP 120
            SGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDCHPLCAWTKWFDVDFPSPGP
Sbjct: 61   SGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDCHPLCAWTKWFDVDFPSPGP 120

Query: 121  HGGDKETYNNIIRSGEKICRRPEEITRLQCRAESHPEVNIEHLGQVVQCSREEGLVCRNQ 180
            HGGDKETYNNIIRSGEKICRRPEEITRLQCRAESHPEVNIEHLGQVVQCSREEGLVCRNQ
Sbjct: 121  HGGDKETYNNIIRSGEKICRRPEEITRLQCRAESHPEVNIEHLGQVVQCSREEGLVCRNQ 180

Query: 181  DQQGPFKMCLNYEVRVLCCETPRGCPVTSVTPYGTSPTNALYPSLSTSMVSASVASTSVA 240
            DQQGPFKMCLNYEVRVLCCETPRGCPVTSVTPYGTSPTNALYPSLSTSMVSASVASTSVA
Sbjct: 181  DQQGPFKMCLNYEVRVLCCETPRGCPVTSVTPYGTSPTNALYPSLSTSMVSASVASTSVA 240

Query: 241  SSSVASSSVAYSTQTCFCNVADRLYPAGSTIYRHRDLAGHCYYALCSQDCQVVRGVDSDC 300
            SSSVASSSVAYSTQTCFCNVADRLYPAGSTIYRHRDLAGHCYYALCSQDCQVVRGVDSDC
Sbjct: 241  SSSVASSSVAYSTQTCFCNVADRLYPAGSTIYRHRDLAGHCYYALCSQDCQVVRGVDSDC 300

Query: 301  PSTTLPPAPATSPSISTSEPVTELGCPNAVPPRKKGETWATPNCSEATCEGNNVISLRPR 360
            PSTTLPPAPATSPSISTSEPVTELGCPNAVPPRKKGETWATPNCSEATCEGNNVISLRPR
Sbjct: 301  PSTTLPPAPATSPSISTSEPVTELGCPNAVPPRKKGETWATPNCSEATCEGNNVISLRPR 360

Query: 361  TCPRVEKPTCANGYPAVKVADQDGCCHHYQCQCVCSGWGDPHYITFDGTYYTFLDNCTYV 420
            TCPRVEKPTCANGYPAVKVADQDGCCHHYQCQCVCSGWGDPHYITFDGTYYTFLDNCTYV
Sbjct: 361  TCPRVEKPTCANGYPAVKVADQDGCCHHYQCQCVCSGWGDPHYITFDGTYYTFLDNCTYV 420

Query: 421  LVQQIVPVYGHFRVLVDNYFCGAEDGLSCPRSIILEYHQDRVVLTRKPVHGVMTNEIIFN 480
            LVQQIVPVYGHFRVLVDNYFCGAEDGLSCPRSIILEYHQDRVVLTRKPVHGVMTNEIIFN
Sbjct: 421  LVQQIVPVYGHFRVLVDNYFCGAEDGLSCPRSIILEYHQDRVVLTRKPVHGVMTNEIIFN 480

Query: 481  NKVVSPGFRKNGIVVSRIGVKMYATIPELGVQVMFSGLIFSVEVPFSKFANNTEGQCXXX 540
            NKVVSPGFRKNGIVVSRIGVKMYATIPELGVQVMFSGLIFSVEVPFSKFANNTEGQC   
Sbjct: 481  NKVVSPGFRKNGIVVSRIGVKMYATIPELGVQVMFSGLIFSVEVPFSKFANNTEGQCXXX 540

Query: 541  XXXXTTPPAPCLPSPICQLILSKVFEPCHTVIPPLLFYEGCVFDRCHMTDLDVVCSSLEL 600
                TTPPAPCLPSPICQLILSKVFEPCHTVIPPLLFYEGCVFDRCHMTDLDVVCSSLEL
Sbjct: 541  XXXXTTPPAPCLPSPICQLILSKVFEPCHTVIPPLLFYEGCVFDRCHMTDLDVVCSSLEL 600

Query: 601  YAALCASHDICIDWRGRTGHMCPFTCPADKVYQPCGPSNPSYCYGNDSASLGALPEAGPI 660
            YAALCASHDICIDWRGRTGHMCPFTCPADKVYQPCGPSNPSYCYGNDSASLGALPEAGPI
Sbjct: 601  YAALCASHDICIDWRGRTGHMCPFTCPADKVYQPCGPSNPSYCYGNDSASLGALPEAGPI 660

Query: 661  TEGCFCPEGMTLFSTSAQVCVPTGCPRCLGPHGEPVKVGHTVGMDCQECTCEAATWTLTC 720
            TEGCFCPEGMTLFSTSAQVCVPTGCPRCLGPHGEPVKVGHTVGMDCQECTCEAATWTLTC
Sbjct: 661  TEGCFCPEGMTLFSTSAQVCVPTGCPRCLGPHGEPVKVGHTVGMDCQECTCEAATWTLTC 720

Query: 721  RPKLCPLPPACPLPGFVPVPAAPQAGQCCPQYSCACNTSRCPKPVGCPEGARAIPTYQEG 780
            RPKLCPLPPACPLPGFVPVPAAPQAGQCCPQYSCACNTSRCPKPVGCPEGARAIPTYQEG
Sbjct: 721  RPKLCPLPPACPLPGFVPVPAAPQAGQCCPQYSCACNTSRCPKPVGCPEGARAIPTYQEG 780

Query: 781  ACCPVQNCSWTVCSINGTLYQPGAVVSSSLCETCRCELPGGPPSDAFVVSCETQICNTHC 840
            ACCPVQNCSWTVCSINGTLYQPGAVVSSSLCETCRCELPGGPPSDAFVVSCETQICNTHC
Sbjct: 781  ACCPVQNCSWTVCSINGTLYQPGAVVSSSLCETCRCELPGGPPSDAFVVSCETQICNTHC 840

Query: 841  PVGFEYQEQSGQCCGTCVQVACVTNTSKSPAHLFYPGETWSDAGNHCVTHQCEKHQDGLV 900
            PVGFEYQEQSGQCCGTCVQVACVTNTSKSPAHLFYPGETWSDAGNHCVTHQCEKHQDGLV
Sbjct: 841  PVGFEYQEQSGQCCGTCVQVACVTNTSKSPAHLFYPGETWSDAGNHCVTHQCEKHQDGLV 900

Query: 901  VVTTKKACPPLSCSLDEARMSKDGCCRFCPPPPPPYQNQSTCAVYHRSLIIQQQGCSSSE 960
            VVTTKKACPPLSCSLDEARMSKDGCCRFCPPPPPPYQNQSTCAVYHRSLIIQQQGCSSSE
Sbjct: 901  VVTTKKACPPLSCSLDEARMSKDGCCRFCPPPPPPYQNQSTCAVYHRSLIIQQQGCSSSE 960

Query: 961  PVRLAYCRGNCGDSSSMYSLEGNTVEHRCQCCQELRTSLRNVTLHCTDGSSRAFSYTEVE 1020
            PVRLAYCRGNCGDSSSMYSLEGNTVEHRCQCCQELRTSLRNVTLHCTDGSSRAFSYTEVE
Sbjct: 961  PVRLAYCRGNCGDSSSMYSLEGNTVEHRCQCCQELRTSLRNVTLHCTDGSSRAFSYTEVE 1020

Query: 1021 ECGCMGRRCPAPGDTQHSEEAEPEPSQEAESGSWERGVPVSPMH 1064
            ECGCMGRRCPAPGDTQHSEEAEPEPSQEAESGSWERGVPVSPMH
Sbjct: 1021 ECGCMGRRCPAPGDTQHSEEAEPEPSQEAESGSWERGVPVSPMH 1064


>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
          Length = 5765

 Score =  578 bits (1491), Expect = e-165
 Identities = 380/1126 (33%), Positives = 528/1126 (46%), Gaps = 163/1126 (14%)

Query: 42   NLCPVPTTSTTSAPTTSTTSGPGTTP-SPVPT-TSTTPVSKTS----------TSHLSVS 89
            +L    TT T +  TT+ +S PGTTP +PV T T+TTP + +S           + L V 
Sbjct: 4682 SLTTTATTITATGSTTNPSSTPGTTPITPVLTSTATTPAATSSKATSSSSPRTATTLPVL 4741

Query: 90   KTTHSQPVTSDCHPLCAWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEI---T 146
             +T ++   +   P+ + T W    +  P        T + I  S          +   T
Sbjct: 4742 TSTATKSTATSFTPIPSSTLW--TTWTVPAQTTTPMSTMSTIHTSSTPETTHTSTVLTTT 4799

Query: 147  RLQCRAESHPEVNIEHLG---------QVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVL 197
                RA +        LG              +   G         G     L     + 
Sbjct: 4800 ATMTRATNSTATPSSTLGTTRILTELTTTATTTAATGSTATLSSTPGT-TWILTEPSTIA 4858

Query: 198  CCETPRGCPVTSVTPYGTSPTNALYPSLST--SMVSASVASTSVA--------------- 240
                P G   T+ +  GT+ T  +  +++T  +  +++V S+S                 
Sbjct: 4859 TVMVPTGSTATASSTLGTAHTPKVVTTMATMPTATASTVPSSSTVGTTRTPAVLPSSLPT 4918

Query: 241  -SSSVASSSV-----------AYSTQTCFCNVADRLYPAGSTIYRHRDLAGHCYYALCSQ 288
             S S  SSSV           ++ +  CFC    + +  G  IY   D AG  +YA+C+Q
Sbjct: 4919 FSVSTVSSSVLTTLRPTGFPSSHFSTPCFCRAFGQFFSPGEVIYNKTDRAGCHFYAVCNQ 4978

Query: 289  DCQVVRGVDSDCPSTTLPPAPATSPSISTSEPVTELGCPNAVPPRKKGETWATPNCSEAT 348
             C + R     CP++   P P +S  +S+  P    GC NA+P R+  ETW   NC+ A 
Sbjct: 4979 HCDIDR-FQGACPTS---PPPVSSAPLSSPSPAP--GCDNAIPLRQVNETWTLENCTVAR 5032

Query: 349  CEGNN-VISLRPRTCPRVEKPTCANGYPAVKVAD-QDGCCHHYQCQCVCSGWGDPHYITF 406
            C G+N V+ L P+    V   TC N +  +KV+D    C  HY+C+C+CS WG  HY TF
Sbjct: 5033 CVGDNRVVLLDPKPVANV---TCVNKHLPIKVSDPSQPCDFHYECECICSMWGGSHYSTF 5089

Query: 407  DGTYYTFLDNCTYVLVQQIVPVYGHFRVLVDNYFCGAE---DGLSCPRSIILEYHQDRVV 463
            DGT YTF  NCTYVL+++I   +G+  + +DN++C A        CPR++ + Y    +V
Sbjct: 5090 DGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTASATAAAARCPRALSIHYKSMDIV 5149

Query: 464  LTRKPVHGVMTNEIIFNNKVVSPGFRKNGIVVSRIG-VKMYATIPELGVQVMFSGLIFSV 522
            LT   VHG     I+F+   VS GF KNG++VS +G   M   IP LGV V F+G +F  
Sbjct: 5150 LTVTMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMRVDIPALGVSVTFNGQVFQA 5209

Query: 523  EVPFSKFANNTEGQCXXXXXXXT------------------------------------T 546
             +P+S F NNTEGQC                                            T
Sbjct: 5210 RLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTWLVPDSRKDGCWAPTGT 5269

Query: 547  PP--------------APCLPSPICQLILSKVFEPCHTVIPPLLFYEGCVFDRCHMTDLD 592
            PP               PC P P+C L+LS+VF  CH ++PP  F+  C+ D C    L+
Sbjct: 5270 PPTASPAAPVSSTPTPTPCPPQPLCDLMLSQVFAECHNLVPPGPFFNACISDHCR-GRLE 5328

Query: 593  VVCSSLELYAALCASHDICIDWRGRTGHMCPFTCPADKVYQPCGPSNPSYCYGNDSASLG 652
            V C SLE YA LC +  +C DWRG TG +C  TCP  KVY+PCGP  P+ C   + +   
Sbjct: 5329 VPCQSLEAYAELCRARGVCSDWRGATGGLCDLTCPPTKVYKPCGPIQPATCNSRNQS--- 5385

Query: 653  ALPEAGPITEGCFCPEGMTLFSTSAQVCVPTGCPRCLGPHGEPVKVGHTVGMDCQECTCE 712
              P+   + EGCFCPE   LF+    +CV   CP C+GP G P   G     +CQ C C+
Sbjct: 5386 --PQLEGMAEGCFCPEDQILFNAHMGICV-QACP-CVGPDGFPKFPGERWVSNCQSCVCD 5441

Query: 713  AATWTLTCRPKLCPL---PPACPLPGFVPVPAAPQAGQCCPQYSCACNTSRCPK--PVGC 767
              + ++ C+P  C     PP C  PGFV V        CCP+  C CNT+ CP+  PV C
Sbjct: 5442 EGSVSVQCKPLPCDAQGQPPPCNRPGFVTVTRPRAENPCCPETVCVCNTTTCPQSLPV-C 5500

Query: 768  PEGARAIPTYQEGACCPVQNCSWTVCSINGTLYQPGAVVSSSL-CETCRCELPGGPPSDA 826
            P G  +I T +EG CCP   C   +CS NGT Y  GA    +L C  C C    G   D 
Sbjct: 5501 PPGQESICTQEEGDCCPTFRCRPQLCSYNGTFYGVGATFPGALPCHMCTC--LSGDTQDP 5558

Query: 827  FVVSCETQIC-NTHCPVGFEYQEQSGQCCGTCVQVACVTNTSKSPAHLFYPGETWSDAG- 884
              V C+   C NT CP GFEY+  +GQCCG CVQ AC+T   + P  L    ETW ++  
Sbjct: 5559 -TVQCQEDACNNTTCPQGFEYKRVAGQCCGECVQTACLTPDGQ-PVQL---NETWVNSHV 5613

Query: 885  NHCVTHQCEKHQDGLVVVTTKKA-CPPLSCSLDEARMSKDGCCRFCPPPPPPYQNQSTCA 943
            ++C  + CE  + G+ ++T + A CP +S      R  K GCC  C         + +C 
Sbjct: 5614 DNCTVYLCEA-EGGVHLLTPQPASCPDVSSCRGSLR--KTGCCYSC--------EEDSCQ 5662

Query: 944  VYHRSLIIQQQGCSSSEPVRLAYCRGNCGDSSSMYSLEGNTVEHRCQCCQELRTSLRNVT 1003
            V   + I+  QGC +   V + +C G+C   +S YS E   ++H+C CCQE R     V 
Sbjct: 5663 VRINTTILWHQGCETE--VNITFCEGSC-PGASKYSAEAQAMQHQCTCCQERRVHEETVP 5719

Query: 1004 LHCTDGSSRAFSYTEVEECGCMGRRCPAPGDTQHSEEAEPEPSQEA 1049
            LHC +GS+   +YT V+ECGC     PAP    H+      P+QEA
Sbjct: 5720 LHCPNGSAILHTYTHVDECGCTPFCVPAPMAPPHTRGF---PAQEA 5762



 Score =  167 bits (424), Expect = 4e-41
 Identities = 113/341 (33%), Positives = 158/341 (46%), Gaps = 46/341 (13%)

Query: 45   PVPTTSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQ---PVTSDC 101
            P P++ TT +P +  T+ PG T     TT+T   SKT TS L  S  T +     VT+ C
Sbjct: 3515 PHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPSKTRTSTLLPSSPTSAPITTVVTTGC 3574

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAESHPEVNIE 161
             P CAW++W D  +P PGP GGD +TY+NI  +G  +C +P     L+CRA++ P V + 
Sbjct: 3575 EPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQP---LGLECRAQAQPGVPLR 3631

Query: 162  HLGQVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCPVT-----SVTPYGTS 216
             LGQVV+CS + GLVCRN++Q G FKMC NYE+RV CC     CP T     + TP  T 
Sbjct: 3632 ELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGH-CPSTPATSSTATPSSTP 3690

Query: 217  PTNALYPSLSTSMVSA-SVASTSVASSSVASSSVAYSTQTCFCNVADRLYPAGSTIYRHR 275
             T  +   L+T+  +  S  ST+  SS+  ++ +     T     A    P GST     
Sbjct: 3691 GTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEPST----TATVTVPTGST----- 3741

Query: 276  DLAGHCYYALCSQDCQVVRGVDSDCPSTTLP------PAPATSPSISTSEPVTELGCP-- 327
                       +   Q   G      + T P        P +SP  +T+ P         
Sbjct: 3742 ---------ATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTP 3792

Query: 328  -----NAVPPRKKGETWATPNCSEATCEGNNVISLRPRTCP 363
                  A+P    G TW     S+ T     + +  P + P
Sbjct: 3793 TATSFTAIPSSSLGTTWT--RLSQTTTPTATMSTATPSSTP 3831



 Score =  167 bits (423), Expect = 5e-41
 Identities = 114/342 (33%), Positives = 159/342 (46%), Gaps = 48/342 (14%)

Query: 45   PVPTTSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTS----D 100
            P P++ TT +P +  T+ PG T +   TT+T   SKT TS L  S  T S P+T+     
Sbjct: 2258 PHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPT-SAPITTVVTMG 2316

Query: 101  CHPLCAWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAESHPEVNI 160
            C P CAW++W D  +P PGP GGD +TY+NI  +G  +C +P     L+CRA++ P V +
Sbjct: 2317 CEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQP---LGLECRAQAQPGVPL 2373

Query: 161  EHLGQVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCPVTSVT-----PYGT 215
              LGQVV+CS + GLVCRN++Q G FKMC NYE+RV CC     CP T  T     P  T
Sbjct: 2374 RELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGH-CPSTPATSSTAMPSST 2432

Query: 216  SPTNALYPSLSTSMVSA-SVASTSVASSSVASSSVAYSTQTCFCNVADRLYPAGSTIYRH 274
              T  +   L+T+  +  S  ST+  SS+  ++ +     T     A    P GST    
Sbjct: 2433 PGTTWILTELTTTATTTESTGSTATPSSTPGTTWILTEPST----TATVTVPTGST---- 2484

Query: 275  RDLAGHCYYALCSQDCQVVRGVDSDCPSTTLP------PAPATSPSISTSEPVTELGCP- 327
                        +   Q   G      + T P        P +SP  +T+ P        
Sbjct: 2485 ----------ATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATT 2534

Query: 328  ------NAVPPRKKGETWATPNCSEATCEGNNVISLRPRTCP 363
                   A+P    G TW     S+ T     + +  P + P
Sbjct: 2535 PTATSFTAIPSSSLGTTWT--RLSQTTTPTATMSTATPSSTP 2574



 Score =  164 bits (414), Expect = 5e-40
 Identities = 90/208 (43%), Positives = 122/208 (58%), Gaps = 13/208 (6%)

Query: 45   PVPTTSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQ---PVTSDC 101
            P P++ TT +P +  T+ PG T +   TT+T   SKT TS L  S  T +     VT+ C
Sbjct: 4072 PHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTTGC 4131

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAESHPEVNIE 161
             P CAW++W D  +P PGP GGD +TY+NI  +G  +C +P     L+CRA++ P V + 
Sbjct: 4132 EPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQP---LGLECRAQAQPGVPLG 4188

Query: 162  HLGQVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCPVTSVT-----PYGTS 216
             LGQVV+CS + GLVCRN++Q G FKMC NYE+RV CC     CP T  T     P  T 
Sbjct: 4189 ELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGH-CPSTPATSSTAMPSSTP 4247

Query: 217  PTNALYPSL-STSMVSASVASTSVASSS 243
             T  +   L +T+  +AS  ST+  SS+
Sbjct: 4248 GTTWILTELTTTATTTASTGSTATPSST 4275



 Score =  163 bits (413), Expect = 7e-40
 Identities = 85/209 (40%), Positives = 121/209 (57%), Gaps = 10/209 (4%)

Query: 45   PVPTTSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDCHPL 104
            P  T ST S    +T+  P  T     + + T   +T T+   ++ TT SQ  T  C P 
Sbjct: 1732 PTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPRTETTMSPLTNTTTSQGTTR-CQPK 1790

Query: 105  CAWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAESHPEVNIEHLG 164
            C WT+WFDVDFP+ G  GGD ET+ NI  +G K+C  P+ I   +CRAE++PEV+I+ +G
Sbjct: 1791 CEWTEWFDVDFPTSGVAGGDMETFENIRAAGGKMCWAPKSI---ECRAENYPEVSIDQVG 1847

Query: 165  QVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCPVTSVTPYGTSPTNA---- 220
            QV+ CS E GL C+N+DQ G F MC NY VRVLCC+    CP T  T    +P++     
Sbjct: 1848 QVLTCSLETGLTCKNEDQTGRFNMCFNYNVRVLCCDDYSHCPSTPATSSTATPSSTPGTT 1907

Query: 221  --LYPSLSTSMVSASVASTSVASSSVASS 247
              L    +T+  +AS  ST+  +S++ ++
Sbjct: 1908 WILTKPTTTATTTASTGSTATPTSTLRTA 1936



 Score =  163 bits (413), Expect = 7e-40
 Identities = 86/209 (41%), Positives = 125/209 (59%), Gaps = 10/209 (4%)

Query: 45   PVPTTSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTS----D 100
            P P++ TT +P +  T+ PG T +   TT+T   SKT TS L  S  T S P+T+     
Sbjct: 2815 PHPSSRTTESPPSPGTTTPGHTRATSRTTATATPSKTRTSTLLPSSPT-SAPITTVVTMG 2873

Query: 101  CHPLCAWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAESHPEVNI 160
            C P CAW++W D  +P PGP GGD +TY+NI  +G  +C +P     L+CRA++ P V +
Sbjct: 2874 CEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQP---LGLECRAQAQPGVPL 2930

Query: 161  EHLGQVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCPVTSVTPYGTSPTNA 220
              LGQVV+CS + GLVCRN++Q G FKMC NYE+RV CC     CP T  T    +P++ 
Sbjct: 2931 RELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGH-CPSTPATSSTATPSST 2989

Query: 221  LYPS-LSTSMVSASVASTSVASSSVASSS 248
               + + T   +A+  + +  S+++ SS+
Sbjct: 2990 PGTTWILTEQTTAATTTATTGSTAIPSST 3018



 Score =  140 bits (353), Expect = 6e-33
 Identities = 100/288 (34%), Positives = 142/288 (49%), Gaps = 42/288 (14%)

Query: 20   CSHRQHNLCSYNQNN--LCL-YSQHNLC-------PVPTTSTTSAPTTSTTSGPGTTPSP 69
            C   +  +C+ +Q +  LC  Y    LC       P P   T+  P+ S ++ P   P+P
Sbjct: 1402 CDRMRGLMCANSQQSPPLCHDYELRVLCCEYVPCGPSPAPGTSPQPSLSASTEPAV-PTP 1460

Query: 70   VPTTST-------TP--------VSKTSTSHLSVSKTTHSQPVTSDCHPLCAWTKWFDVD 114
              TT+T       TP         S+T +S   V+  T S P T+ C P C WT+WFD D
Sbjct: 1461 TQTTATEKTTLWVTPSIRSTAALTSQTGSSSGPVT-VTPSAPGTTTCQPRCQWTEWFDED 1519

Query: 115  FPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAESHPEVNIEHLGQVVQCSREEG 174
            +P     GGD E+Y+ I  +G  +C++P++I   +C+AES P   +  +GQ V C    G
Sbjct: 1520 YPKSEQLGGDVESYDKIRAAGGHLCQQPKDI---ECQAESFPNWTLAQVGQKVHCDVHFG 1576

Query: 175  LVCRNQDQQGPFKMCLNYEVRVLCCETP--RG-----CPVTSVTPYGTSPTNALY----P 223
            LVCRN +Q+G FKMC NY +RVLCC     RG      P T +    T+ T AL+    P
Sbjct: 1577 LVCRNWEQEGVFKMCYNYRIRVLCCSDDHCRGRATTPPPTTELETATTTTTQALFSTPQP 1636

Query: 224  SLSTSMVSASVAS-TSVASSSVASSSVAYSTQTCFCNVADRLYPAGST 270
            + S  +  A  AS T+V + S   +S  Y++            PAGST
Sbjct: 1637 TSSPGLTRAPPASTTAVPTLSEGLTSPRYTSTLGTATTGGPTTPAGST 1684



 Score =  109 bits (272), Expect = 2e-23
 Identities = 65/190 (34%), Positives = 100/190 (52%), Gaps = 19/190 (10%)

Query: 72   TTSTTPVSKTSTSHLSVSKTTHSQPVTSDC-HPLCAWTKWFDVDFPSPGPHGGDKETYNN 130
            T +TTP + T T+ +  S T+ + PV++ C   +C W+ W++   P PG  GGD ET+ N
Sbjct: 1308 TPATTPFTFT-TAWVPHSTTSPALPVSTVCVREVCRWSSWYNGHRPEPGLGGGDFETFEN 1366

Query: 131  IIRSGEKICRRPEEITRLQCRAESHPEVNIEHLGQVVQCSREEGLVCRNQDQQGPFKMCL 190
            + + G ++C     +  ++CRA   P++ +E LGQ V C R  GL+C N  Q  P  +C 
Sbjct: 1367 LRQRGYQVC---PVLADIECRAAQLPDMPLEELGQQVDCDRMRGLMCANSQQSPP--LCH 1421

Query: 191  NYEVRVLCCE------------TPRGCPVTSVTPYGTSPTNALYPSLSTSMVSASVASTS 238
            +YE+RVLCCE            +P+     S  P   +PT       +T  V+ S+ ST+
Sbjct: 1422 DYELRVLCCEYVPCGPSPAPGTSPQPSLSASTEPAVPTPTQTTATEKTTLWVTPSIRSTA 1481

Query: 239  VASSSVASSS 248
              +S   SSS
Sbjct: 1482 ALTSQTGSSS 1491



 Score = 94.7 bits (234), Expect = 4e-19
 Identities = 112/482 (23%), Positives = 171/482 (35%), Gaps = 69/482 (14%)

Query: 386 CHHYQCQCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVLVDNYFCGAED 445
           C    C   CS  G  H  T+D   Y    +C+YVL ++       F VL +   CG  D
Sbjct: 419 CQDLPCPGTCSVQGGAHISTYDEKLYDLHGDCSYVLSKKCAD--SSFTVLAELRKCGLTD 476

Query: 446 GLSCPRSIILEYHQDRVVLTRKPVHGVMTNEIIFNNKVVSPG---FRKNG---IVVSRIG 499
             +C +++ L        +  +   GV  N I     + +     F  +    +V + +G
Sbjct: 477 NENCLKAVTLSLDGGDTAIRVQADGGVFLNSIYTQLPLSAANITLFTPSSFFIVVQTGLG 536

Query: 500 VKMYATIPELGVQVM-------------------------FSGLIFSVEVPFSKFANNTE 534
           +++   +  L +QV                          F+ L   VE   + FAN  +
Sbjct: 537 LQLLVQLVPL-MQVFVRLDPAHQGQMCGLCGNFNQNQADDFTALSGVVEATGAAFANTWK 595

Query: 535 GQCXXXXXXXTTPPAPCLPSPI--------CQLIL--SKVFEPCHTVIPPLLFYEGCVFD 584
            Q        +    PC  S          C  +   +  F  CH++I P  F+  C+FD
Sbjct: 596 AQAACANARNSFED-PCSLSVENENYARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFD 654

Query: 585 RCHM-TDLDVVCSSLELYAALCASHDICI-DWRGRTGHMCPFTCPADKVYQPCGPSNPSY 642
            C+     D +C++L  Y   CA+  + + DWR          CP  + Y     +    
Sbjct: 655 TCNCERSEDCLCAALSSYVHACAAKGVQLSDWRDGVCTKYMQNCPKSQRYAYVVDACQPT 714

Query: 643 CYGNDSASLGALPEAGPITEGCFCPEGMTLFSTSAQVCVPT-GCPRCLGPHGEPVKVGHT 701
           C G   A +       P+ +GC CP G   F   A  CVP   CP C   HG  +  G  
Sbjct: 715 CRGLSEADVTCSVSFVPV-DGCTCPAG--TFLNDAGACVPAQECP-CYA-HGTVLAPGEV 769

Query: 702 VGMDCQECTCEAATWTLTCRPKLCPLPPACPLPGFVPVPAAPQAG-------QCCPQYSC 754
           V  +   C+C      L+C          C  P      +   AG       + C     
Sbjct: 770 VHDEGAVCSCTGG--KLSCLGASLQKSTGCAAPMVYLDCSNSSAGTPGAECLRSCHTLDV 827

Query: 755 ACNTSRCPKPVGCPEGARAIPTYQEGACCPVQNCSWTVCSINGTLYQPGAVVSSSLCETC 814
            C ++ C     CP G   + +   G C   ++C    C  N   Y+PG  +    C TC
Sbjct: 828 GCFSTHCVSGCVCPPG---LVSDGSGGCIAEEDCP---CVHNEATYKPGETIRVD-CNTC 880

Query: 815 RC 816
            C
Sbjct: 881 TC 882



 Score = 88.6 bits (218), Expect = 3e-17
 Identities = 90/373 (24%), Positives = 133/373 (35%), Gaps = 63/373 (16%)

Query: 394 VCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVLVDNYFCGAEDGLSCPRSI 453
           VCS WGD HY TFDG  + F   C YV  +       H R   +++      GL   R +
Sbjct: 76  VCSTWGDFHYKTFDGDVFRFPGLCNYVFSE-------HCRAAYEDFNVQLRRGLVGSRPV 128

Query: 454 ILEYHQDRVVLTRKPVHGVMTNEIIFNNKVVSPGFRKNGIVVSRIGVKMYATIPELGVQV 513
           +       V+  +  V       ++ N +     + + G++V + G  +  +I  L +  
Sbjct: 129 VTRV----VIKAQGLVLEASNGSVLINGQREELPYSRTGLLVEQSGDYIKVSI-RLVLTF 183

Query: 514 MFSGLIFSVEVPFSKFANNTEGQCXXXXXXXT-----------TP-----------PAPC 551
           +++G   ++     K+AN T G C                   TP           P   
Sbjct: 184 LWNGEDSALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLTPLQFGNLQKLDGPTEQ 243

Query: 552 LPSP-------------IC-QLILSKVFEPCHTVIPPLLFYEGCVFDRCHMTDLDVVCSS 597
            P P             IC + +L   F  CH ++    +   C  D C        C++
Sbjct: 244 CPDPLPLPAGNCTDEEGICHRTLLGPAFAECHALVDSTAYLAACAQDLCRCPTCP--CAT 301

Query: 598 LELYAALCASHDICIDWRGRTGHMCPFTCPADKVYQPCGPSNPSYCYGNDSASLGALPEA 657
              Y+  CA H        R   +CP TCP +  +Q CG      C     A L      
Sbjct: 302 FVEYSRQCA-HAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSNPQRAQLC----E 356

Query: 658 GPITEGCFCPEGMT---LFSTSAQVCVPTG-CPRCLGPHGEPVKVGHTVGMDCQECTCEA 713
               +GCFCP G +   L   +   C+P G CP   G  G     G +    C  CTC  
Sbjct: 357 DHCVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHG--GRTYSPGTSFNTTCSSCTCSG 414

Query: 714 ATWTLTCRPKLCP 726
             W   C+   CP
Sbjct: 415 GLW--QCQDLPCP 425



 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 52/187 (27%), Positives = 68/187 (36%), Gaps = 30/187 (16%)

Query: 547  PPAPCLPSPI--------CQLILSKVFEPCHTVIPPLLFYEGCVFDRCHMT---DLDVVC 595
            P  PC  +P         C ++    F  C + +    +YE CV D C      D +  C
Sbjct: 1070 PKDPCTANPFRKSWAQKQCSILHGPTFAACRSQVDSTKYYEACVNDACACDSGGDCECFC 1129

Query: 596  SSLELYAALCASHDICIDWRGRTGHMCPFTCP-------ADKVYQPCGPSNPSYCYGNDS 648
            +++  YA  C    +C+ W  RT   CP  C         +  YQPCG      C     
Sbjct: 1130 TAVAAYAQACHDAGLCVSW--RTPDTCPLFCDFYNPHGGCEWHYQPCGAPCLKTCRNPSG 1187

Query: 649  ASLGALPEAGPITEGCF--CPEGMTLFSTSAQVCVPTGCPRCLGPHGEPVKVGHTV--GM 704
              L  LP      EGC+  CP     F+     CV   C  C    G    VG  V    
Sbjct: 1188 HCLVDLPG----LEGCYPKCPPSQPFFNEDQMKCV-AQC-GCYDKDGNYYDVGARVPTAE 1241

Query: 705  DCQECTC 711
            +CQ C C
Sbjct: 1242 NCQSCNC 1248



 Score = 61.2 bits (147), Expect = 5e-09
 Identities = 74/312 (23%), Positives = 112/312 (35%), Gaps = 37/312 (11%)

Query: 167 VQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRG-------CPVTSVTPYGTSPTN 219
           VQ S     VC    Q  P      Y V   C  T RG       C V+ V   G +   
Sbjct: 681 VQLSDWRDGVCTKYMQNCPKSQRYAYVVDA-CQPTCRGLSEADVTCSVSFVPVDGCTCPA 739

Query: 220 ALYPSLSTSMVSASVASTSVASSSVASSSVAYSTQTCFCNVADRLYPAGSTIYRHRDLAG 279
             + + + + V A         + +A   V +           +L   G+++ +    A 
Sbjct: 740 GTFLNDAGACVPAQECPCYAHGTVLAPGEVVHDEGAVCSCTGGKLSCLGASLQKSTGCAA 799

Query: 280 HCYYALCSQDCQVVRGVDSDCPSTTLPPAPATSPSISTSEPVTELGCPNAVPPRKKGETW 339
              Y  CS       G +      TL     ++  +S         CP  +     G   
Sbjct: 800 PMVYLDCSNSSAGTPGAECLRSCHTLDVGCFSTHCVSGCV------CPPGLVSDGSGGCI 853

Query: 340 ATPNC----SEATCEGNNVISLRPRTCPRVEKPTCANGYPAVKVADQDGCCHHYQCQCVC 395
           A  +C    +EAT +    I +   TC      TC N         +   C H  C   C
Sbjct: 854 AEEDCPCVHNEATYKPGETIRVDCNTC------TCRN---------RRWECSHRLCLGTC 898

Query: 396 SGWGDPHYITFDGTYYTFLDNCTYVLVQQIV---PVYGHFRVLVDNYFCGAEDGLSCPRS 452
             +GD H+ITFDG  Y+F  +C Y+L Q        +G FR++ +N  CG   G +C ++
Sbjct: 899 VAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNTTHGTFRIVTENIPCGT-TGTTCSKA 957

Query: 453 IILEYHQDRVVL 464
           I L      ++L
Sbjct: 958 IKLFVESYELIL 969



 Score = 43.9 bits (102), Expect = 8e-04
 Identities = 26/59 (44%), Positives = 36/59 (61%), Gaps = 3/59 (5%)

Query: 42   NLCPVPTTSTTSAPTTSTTSGPGTTPSP--VPTTSTTPVSKTST-SHLSVSKTTHSQPV 97
            +L    TT T +  TT+ +S PGTTP P  + TT+TTP + +ST +  S   TTH+ PV
Sbjct: 2692 SLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPV 2750



 Score = 43.9 bits (102), Expect = 8e-04
 Identities = 26/59 (44%), Positives = 36/59 (61%), Gaps = 3/59 (5%)

Query: 42   NLCPVPTTSTTSAPTTSTTSGPGTTPSP--VPTTSTTPVSKTST-SHLSVSKTTHSQPV 97
            +L    TT T +  TT+ +S PGTTP P  + TT+TTP + +ST +  S   TTH+ PV
Sbjct: 3392 SLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPV 3450



 Score = 43.9 bits (102), Expect = 8e-04
 Identities = 26/59 (44%), Positives = 36/59 (61%), Gaps = 3/59 (5%)

Query: 42   NLCPVPTTSTTSAPTTSTTSGPGTTPSP--VPTTSTTPVSKTST-SHLSVSKTTHSQPV 97
            +L    TT T +  TT+ +S PGTTP P  + TT+TTP + +ST +  S   TTH+ PV
Sbjct: 3949 SLITTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPV 4007



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 25/59 (42%), Positives = 36/59 (61%), Gaps = 3/59 (5%)

Query: 42   NLCPVPTTSTTSAPTTSTTSGPGTTPSP--VPTTSTTPVSKTST-SHLSVSKTTHSQPV 97
            +L    TT T +  TT+ +S PGTTP P  + TT+TTP + ++T +  S   TTH+ PV
Sbjct: 2135 SLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSNTVTPSSALGTTHTPPV 2193



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 26/82 (31%), Positives = 36/82 (43%), Gaps = 6/82 (7%)

Query: 250  AYSTQTCFCNVADRLYPAGSTIYRHRDLAGHCYYALCSQDCQVVRGVDSDCPSTTLPPAP 309
            A+S + C C   DR Y     IY   D  G C  A+C  +  ++R   + CP T     P
Sbjct: 1256 AHSLEACTCTYEDRTYSYQDVIYNTTDGLGACLIAICGSNGTIIRKAVA-CPGT-----P 1309

Query: 310  ATSPSISTSEPVTELGCPNAVP 331
            AT+P   T+  V       A+P
Sbjct: 1310 ATTPFTFTTAWVPHSTTSPALP 1331



 Score = 38.9 bits (89), Expect = 0.026
 Identities = 25/65 (38%), Positives = 31/65 (47%), Gaps = 9/65 (13%)

Query: 663 GCFCPEGMTLFSTSAQVCVPT-GCPRCLGPHGEPV-KVGHTVGMDCQECTCEAATWTLTC 720
           GC CP G  L S  +  C+    CP C+  H E   K G T+ +DC  CTC    W   C
Sbjct: 837 GCVCPPG--LVSDGSGGCIAEEDCP-CV--HNEATYKPGETIRVDCNTCTCRNRRW--EC 889

Query: 721 RPKLC 725
             +LC
Sbjct: 890 SHRLC 894



 Score = 37.0 bits (84), Expect = 0.099
 Identities = 27/91 (29%), Positives = 40/91 (43%), Gaps = 18/91 (19%)

Query: 26   NLC-SYNQNNLCLYSQHNLCP-VPTTSTTSAP---------------TTSTTSGPGTTPS 68
            N+C +YN   LC    ++ CP  P TS+T+ P               T +TT+  G+T +
Sbjct: 1870 NMCFNYNVRVLCC-DDYSHCPSTPATSSTATPSSTPGTTWILTKPTTTATTTASTGSTAT 1928

Query: 69   PVPTTSTTPVSKTSTSHLSVSKTTHSQPVTS 99
            P  T  T P  K  T+  +    T S+   S
Sbjct: 1929 PTSTLRTAPPPKVLTTTATTPTVTSSKATPS 1959



 Score = 36.2 bits (82), Expect = 0.17
 Identities = 23/50 (46%), Positives = 29/50 (58%), Gaps = 1/50 (2%)

Query: 48   TTSTTSAPTTSTTSGPGTTPSP-VPTTSTTPVSKTSTSHLSVSKTTHSQP 96
            TT TTS  T + +S PGTT +P V TT+TT V+  S +  S S  T   P
Sbjct: 3898 TTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTP 3947



 Score = 36.2 bits (82), Expect = 0.17
 Identities = 26/70 (37%), Positives = 33/70 (47%), Gaps = 18/70 (25%)

Query: 48   TTSTTSAPTTSTTSGPGTTPSPVP---------TTST---------TPVSKTSTSHLSVS 89
            +T+TT   TT TTSG   TPS +P         TT+T         TP S T TS    S
Sbjct: 4623 STTTTPTTTTPTTSGSTVTPSSIPGTTHTARVLTTTTTTVATGSMATPSSSTQTSGTPPS 4682

Query: 90   KTTHSQPVTS 99
             TT +  +T+
Sbjct: 4683 LTTTATTITA 4692



 Score = 35.8 bits (81), Expect = 0.22
 Identities = 23/60 (38%), Positives = 31/60 (51%), Gaps = 10/60 (16%)

Query: 48   TTSTTSAPTTSTT-------SGPGTTPSP---VPTTSTTPVSKTSTSHLSVSKTTHSQPV 97
            T  TT  PTT+TT       S PGT  +P   + TT+T   S ++ +  SV  TTH+  V
Sbjct: 3862 TAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVPGTTHTPTV 3921



 Score = 35.4 bits (80), Expect = 0.29
 Identities = 29/113 (25%), Positives = 44/113 (38%), Gaps = 20/113 (17%)

Query: 758 TSRCPKPVGCPEGARAIPTYQEGACC-PVQNCSWTVCS--INGTLYQPGAVVSSSLCETC 814
           T +CP P+  P G     T +EG C   +   ++  C   ++ T Y          C TC
Sbjct: 241 TEQCPDPLPLPAGNC---TDEEGICHRTLLGPAFAECHALVDSTAYLAACAQDLCRCPTC 297

Query: 815 ----------RCELPGGPPSDAFVVSCETQICNTHCPVGFEYQEQSGQCCGTC 857
                     +C   GG P +     C  ++C   CP+  ++QE    C  TC
Sbjct: 298 PCATFVEYSRQCAHAGGQPRNW---RCP-ELCPRTCPLNMQHQECGSPCTDTC 346



 Score = 35.4 bits (80), Expect = 0.29
 Identities = 25/60 (41%), Positives = 33/60 (55%), Gaps = 10/60 (16%)

Query: 48   TTSTTSAPTTSTT-------SGPGT--TPSPVPTTSTTPVSKTST-SHLSVSKTTHSQPV 97
            T  TT  PTT+TT       S PGT  TP    +T+TTP ++ ST +  S+  TTH+  V
Sbjct: 2048 TAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATV 2107



 Score = 35.4 bits (80), Expect = 0.29
 Identities = 25/60 (41%), Positives = 33/60 (55%), Gaps = 10/60 (16%)

Query: 48   TTSTTSAPTTSTT-------SGPGT--TPSPVPTTSTTPVSKTST-SHLSVSKTTHSQPV 97
            T  TT  PTT+TT       S PGT  TP    +T+TTP ++ ST +  S+  TTH+  V
Sbjct: 3305 TAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATV 3364



 Score = 35.4 bits (80), Expect = 0.29
 Identities = 22/57 (38%), Positives = 31/57 (54%), Gaps = 4/57 (7%)

Query: 45   PVPTTSTTSAPTTSTTSGPGTT---PSPVPTTSTTPVSKTSTSH-LSVSKTTHSQPV 97
            PV T++ T +  TS T  P +T      +P  +TTPV+  ST H  S  +TTH+  V
Sbjct: 4312 PVLTSTATKSTATSVTPIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTV 4368



 Score = 35.0 bits (79), Expect = 0.38
 Identities = 23/62 (37%), Positives = 30/62 (48%), Gaps = 10/62 (16%)

Query: 48   TTSTTSAPTTSTTSGPGTTPSPVPTTST----------TPVSKTSTSHLSVSKTTHSQPV 97
            TT TT   T + +S PGTT +P   T+T          TP S T TS    S TT +  +
Sbjct: 2641 TTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTI 2700

Query: 98   TS 99
            T+
Sbjct: 2701 TA 2702



 Score = 34.7 bits (78), Expect = 0.49
 Identities = 24/66 (36%), Positives = 33/66 (50%), Gaps = 9/66 (13%)

Query: 45   PVPTTSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVT-SDCHP 103
            P+P   TT+A T + TS   T  S + TT T PV  T+        TTH + ++ S  H 
Sbjct: 2717 PIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTA-------TTHGRSLSPSSPHT 2769

Query: 104  L-CAWT 108
            +  AWT
Sbjct: 2770 VRTAWT 2775



 Score = 34.7 bits (78), Expect = 0.49
 Identities = 23/59 (38%), Positives = 27/59 (45%), Gaps = 20/59 (33%)

Query: 46   VPTTSTT--------------------SAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTS 84
            VPTT+TT                    S  TT TTSG   TPS VP T+ TP   T+T+
Sbjct: 3868 VPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVPGTTHTPTVLTTTT 3926



 Score = 34.7 bits (78), Expect = 0.49
 Identities = 24/66 (36%), Positives = 33/66 (50%), Gaps = 9/66 (13%)

Query: 45   PVPTTSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVT-SDCHP 103
            P+P   TT+A T + TS   T  S + TT T PV  T+        TTH + ++ S  H 
Sbjct: 3974 PIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTA-------TTHGRSLSPSSPHT 4026

Query: 104  L-CAWT 108
            +  AWT
Sbjct: 4027 VRTAWT 4032



 Score = 34.7 bits (78), Expect = 0.49
 Identities = 23/65 (35%), Positives = 31/65 (47%), Gaps = 15/65 (23%)

Query: 48   TTSTTSAPTTSTT-------SGPGTTPSP--------VPTTSTTPVSKTSTSHLSVSKTT 92
            T  TT  PTT+TT       S PGT  +P         PTT+T   S ++ +  S+  TT
Sbjct: 4590 TAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTTTPTTSGSTVTPSSIPGTT 4649

Query: 93   HSQPV 97
            H+  V
Sbjct: 4650 HTARV 4654



 Score = 34.3 bits (77), Expect = 0.64
 Identities = 22/60 (36%), Positives = 28/60 (46%), Gaps = 3/60 (5%)

Query: 49   TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDCHPLCAWT 108
            T  T+A TT+ T+G    PS  P T+  P   TST   + + T  S   TS   P  A T
Sbjct: 2997 TEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTST---ATTPTATSSKATSSSSPRTATT 3053



 Score = 33.9 bits (76), Expect = 0.84
 Identities = 18/61 (29%), Positives = 29/61 (47%)

Query: 48   TTSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDCHPLCAW 107
            TT+ T+  TT +T+ P +TP   P       + T+ +  S   T+ S P T+   P+   
Sbjct: 3000 TTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATTPTATSSKATSSSSPRTATTLPVLTS 3059

Query: 108  T 108
            T
Sbjct: 3060 T 3060



 Score = 33.5 bits (75), Expect = 1.1
 Identities = 73/343 (21%), Positives = 113/343 (32%), Gaps = 58/343 (16%)

Query: 43   LCPVPTTSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDCH 102
            L  + TT+TT+A T ST + P +TP   P         T+ +  S   T+ S P T+   
Sbjct: 4253 LTELTTTATTTASTGSTAT-PSSTPGTAPPPKVLTSPATTPTATSSKATSSSSPRTATTL 4311

Query: 103  PLCAWTKWFDVD---FPSPGPHGGDKETYNNIIRSGEKICRRPEEITR-LQCRAESHPEV 158
            P+   T          P P    G   T              PE+ T  +   +  HP  
Sbjct: 4312 PVLTSTATKSTATSVTPIPSSTLGTTGTL-------------PEQTTTPVATMSTIHPSS 4358

Query: 159  NIE--HLGQVV--QCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCPVTSVTPYG 214
              E  H   V+  + +        +     P    +  E+      T    P  + TP  
Sbjct: 4359 TPETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATGP--TATPSS 4416

Query: 215  TSPTNALYPSL-STSMVSASVASTSVASSSVASSSVAYSTQTCFCNVADRLYPAGSTIYR 273
            T  T  +   L +T+  +AS  ST+  SS+  ++ +     T     A    P GST   
Sbjct: 4417 TPGTTWILTELTTTATTTASTGSTATPSSTPGTTWILTEPST----TATVTVPTGST--- 4469

Query: 274  HRDLAGHCYYALCSQDCQVVRGVDSDCPSTTLP------PAPATSPSISTSEPVTELGCP 327
                         +   Q   G      + T P        P++SP  +T+ P       
Sbjct: 4470 -----------ATASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGTATALPALRSTAT 4518

Query: 328  -------NAVPPRKKGETWATPNCSEATCEGNNVISLRPRTCP 363
                    A+P    G TW     S+ T     + +  P + P
Sbjct: 4519 TPTATSFTAIPSSSLGTTWT--RLSQTTTPTATMSTATPSSTP 4559



 Score = 33.5 bits (75), Expect = 1.1
 Identities = 22/69 (31%), Positives = 32/69 (46%), Gaps = 6/69 (8%)

Query: 45   PVPTTSTTSAP-----TTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTS 99
            P  +T T+  P     T +T +  G+T +P  T  TTP++   TS  +    T S+  TS
Sbjct: 4670 PSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPITPVLTSTATTPAATSSK-ATS 4728

Query: 100  DCHPLCAWT 108
               P  A T
Sbjct: 4729 SSSPRTATT 4737



 Score = 32.7 bits (73), Expect = 1.9
 Identities = 23/58 (39%), Positives = 33/58 (56%), Gaps = 6/58 (10%)

Query: 45   PVPTTSTTSAPTTSTTSGP----GTTPSPVPTTSTTPVSKTSTSH-LSVSKTTHSQPV 97
            PV T++ T +  TS T  P    GTT + +P  +TTP++  ST H  S  +TTH+  V
Sbjct: 3055 PVLTSTATKSTATSFTPIPSFTLGTTGT-LPEQTTTPMATMSTIHPSSTPETTHTSTV 3111



 Score = 32.0 bits (71), Expect = 3.2
 Identities = 22/62 (35%), Positives = 33/62 (53%), Gaps = 11/62 (17%)

Query: 47   PTTSTTSAPTTSTTSGPGTTPSPVP----------TTSTTPVSKTST-SHLSVSKTTHSQ 95
            P T+ T+   T+TT+G   TPS  P          +T+TTP ++ ST +  S+  TTH+ 
Sbjct: 2603 PGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTPTTRGSTVTPSSIPGTTHTP 2662

Query: 96   PV 97
             V
Sbjct: 2663 TV 2664



 Score = 32.0 bits (71), Expect = 3.2
 Identities = 15/32 (46%), Positives = 19/32 (59%)

Query: 53   SAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTS 84
            S  TT TT G   TPS +P T+ TP   T+T+
Sbjct: 2638 STTTTPTTRGSTVTPSSIPGTTHTPTVLTTTT 2669



 Score = 31.6 bits (70), Expect = 4.2
 Identities = 34/117 (29%), Positives = 48/117 (41%), Gaps = 24/117 (20%)

Query: 13   SWNYSQPCSHRQH----NLC-SYNQNNLCLYSQHNLCP-VPTTSTTSAP----------- 55
            S ++   C +R+      +C +Y     C    H  CP  P TS+T+ P           
Sbjct: 4197 SLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGH--CPSTPATSSTAMPSSTPGTTWILT 4254

Query: 56   ---TT-STTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDCHPLCAWT 108
               TT +TT+  G+T +P  T  T P  K  TS  + + T  S   TS   P  A T
Sbjct: 4255 ELTTTATTTASTGSTATPSSTPGTAPPPKVLTSP-ATTPTATSSKATSSSSPRTATT 4310



 Score = 31.2 bits (69), Expect = 5.4
 Identities = 19/54 (35%), Positives = 26/54 (48%), Gaps = 10/54 (18%)

Query: 49   TSTTSAPTTSTTSGPGTTPSPVP----------TTSTTPVSKTSTSHLSVSKTT 92
            T  T+A TT+  +GP  TPS  P          TT+T  V   ST+  S ++ T
Sbjct: 3139 TELTTAATTTAATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRAT 3192



 Score = 31.2 bits (69), Expect = 5.4
 Identities = 28/82 (34%), Positives = 37/82 (45%), Gaps = 5/82 (6%)

Query: 43   LCPVPTTSTTSAPTTST---TSGPGTT--PSPVPTTSTTPVSKTSTSHLSVSKTTHSQPV 97
            L  + TT+TT+  T ST   +S PGTT   +   TT+T  V   ST+  S ++ T   P 
Sbjct: 3696 LTKLTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPH 3755

Query: 98   TSDCHPLCAWTKWFDVDFPSPG 119
             S        T      F SPG
Sbjct: 3756 VSTTATTPTVTSSKATPFSSPG 3777



 Score = 30.8 bits (68), Expect = 7.1
 Identities = 25/72 (34%), Positives = 33/72 (45%), Gaps = 15/72 (20%)

Query: 43   LCPVPTTSTTSAPTT-----STTSGPGTTPSPVPTTST----------TPVSKTSTSHLS 87
            L P    STT+ PTT     + +S PGTT +    T+T          TP S T TS   
Sbjct: 2074 LTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTP 2133

Query: 88   VSKTTHSQPVTS 99
             S TT +  +T+
Sbjct: 2134 PSLTTTATTITA 2145



 Score = 30.8 bits (68), Expect = 7.1
 Identities = 25/72 (34%), Positives = 33/72 (45%), Gaps = 15/72 (20%)

Query: 43   LCPVPTTSTTSAPTT-----STTSGPGTTPSPVPTTST----------TPVSKTSTSHLS 87
            L P    STT+ PTT     + +S PGTT +    T+T          TP S T TS   
Sbjct: 3331 LTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTP 3390

Query: 88   VSKTTHSQPVTS 99
             S TT +  +T+
Sbjct: 3391 PSLTTTATTITA 3402



 Score = 30.8 bits (68), Expect = 7.1
 Identities = 21/57 (36%), Positives = 27/57 (47%), Gaps = 2/57 (3%)

Query: 48   TTSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDCHPL 104
            T  TT+A TT  T    T  S   T  TT V  T+T+  +V  T  S P T+   P+
Sbjct: 3838 TVLTTTATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTV--TPSSSPGTARTPPV 3892



 Score = 30.4 bits (67), Expect = 9.3
 Identities = 27/81 (33%), Positives = 33/81 (40%), Gaps = 23/81 (28%)

Query: 46   VPTTSTT--------------------SAPTTSTTSGPGTTPSPVP-TTSTTPVSKTSTS 84
            VPTT+TT                    S  TT TT G   TPS +P TT T  V  T+T+
Sbjct: 2054 VPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTT 2113

Query: 85   HLSVSK--TTHSQPVTSDCHP 103
             ++     T  S   TS   P
Sbjct: 2114 TVATGSMATPSSSTQTSGTPP 2134



 Score = 30.4 bits (67), Expect = 9.3
 Identities = 17/44 (38%), Positives = 25/44 (56%), Gaps = 5/44 (11%)

Query: 46   VPTTSTTSAPTTSTTSGPGTTPS-----PVPTTSTTPVSKTSTS 84
            V TT+TT+   T + + P +TP       VPTT+TT  + T +S
Sbjct: 3282 VLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSS 3325



 Score = 30.4 bits (67), Expect = 9.3
 Identities = 27/81 (33%), Positives = 33/81 (40%), Gaps = 23/81 (28%)

Query: 46   VPTTSTT--------------------SAPTTSTTSGPGTTPSPVP-TTSTTPVSKTSTS 84
            VPTT+TT                    S  TT TT G   TPS +P TT T  V  T+T+
Sbjct: 3311 VPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTT 3370

Query: 85   HLSVSK--TTHSQPVTSDCHP 103
             ++     T  S   TS   P
Sbjct: 3371 TVATGSMATPSSSTQTSGTPP 3391



 Score = 30.4 bits (67), Expect = 9.3
 Identities = 21/65 (32%), Positives = 32/65 (49%), Gaps = 11/65 (16%)

Query: 46   VPTTSTTSAPTTSTTSGPGTTPS-----PVPTTSTTPVSKTSTSHLSVSKT------THS 94
            V TT+ T+   T + + P +TP       VPTT+TT  + T +S    ++T      T +
Sbjct: 3839 VLTTTATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTT 3898

Query: 95   QPVTS 99
             P TS
Sbjct: 3899 TPTTS 3903


>gi|161019170 mucin 5AC [Homo sapiens]
          Length = 6207

 Score =  546 bits (1408), Expect = e-155
 Identities = 327/938 (34%), Positives = 458/938 (48%), Gaps = 121/938 (12%)

Query: 201  TPRGCPVTSVTPYGTSPTNALYPSLSTSMVSASVASTSVASSSVASSSVAYSTQTCFCNV 260
            T     V S +  GT+ T A+ PS   +   ++V+S+ + +        ++ +  CFC  
Sbjct: 5210 TATASTVPSSSTVGTTRTPAVLPSSLPTFSVSTVSSSVLTTLRPTGFPSSHFSTPCFCRA 5269

Query: 261  ADRLYPAGSTIYRHRDLAGHCYYALCSQDCQVVRGVDSDCPSTTLPPAPATSPSISTSEP 320
              + +  G  IY   D AG  +YA+C+Q C + R     CP++   P P +S  +S+  P
Sbjct: 5270 FGQFFSPGEVIYNKTDRAGCHFYAVCNQHCDIDR-FQGACPTS---PPPVSSAPLSSPSP 5325

Query: 321  VTELGCPNAVPPRKKGETWATPNCSEATCEGNN-VISLRPRTCPRVEKPTCANGYPAVKV 379
                GC NA+P R+  ETW   NC+ A C G+N V+ L P+    V   TC N +  +KV
Sbjct: 5326 AP--GCDNAIPLRQVNETWTLENCTVARCVGDNRVVLLDPKPVANV---TCVNKHLPIKV 5380

Query: 380  AD-QDGCCHHYQCQC-------------VCSGWGDPHYITFDGTYYTFLDNCTYVLVQQI 425
            +D    C  HY+C+C             +CS WG  HY TFDGT YTF  NCTYVL+++I
Sbjct: 5381 SDPSQPCDFHYECECECVGGRGITPGAGICSMWGGSHYSTFDGTSYTFRGNCTYVLMREI 5440

Query: 426  VPVYGHFRVLVDNYFC-----GAEDGLSCPRSIILEYHQDRVVLTRKPVHGVMTNEIIFN 480
               +G+  + +DN++C      A     CPR++ + Y    +VLT   VHG     I+F+
Sbjct: 5441 HARFGNLSLYLDNHYCTASATAAAAAARCPRALSIHYKSMDIVLTVTMVHGKEEGLILFD 5500

Query: 481  NKVVSPGFRKNGIVVSRIGVK-MYATIPELGVQVMFSGLIFSVEVPFSKFANN------- 532
               VS GF KNG++VS +G   M   IP LGV V F+G +F   +P+S F NN       
Sbjct: 5501 QIPVSSGFSKNGVLVSVLGTTTMRVDIPALGVSVTFNGQVFQARLPYSLFHNNTEGQCGT 5560

Query: 533  ---------------TEGQCXXXXXXXTTP----------------------------PA 549
                           T   C         P                            P 
Sbjct: 5561 CTNNQRDDCLQRDGTTAASCKDMAKTWLVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPT 5620

Query: 550  PCLPSPICQLILSKVFEPCHTVIPPLLFYEGCVFDRCHMTDLDVVCSSLELYAALCASHD 609
            PC P P+C L+LS+VF  CH ++PP  F+  C+ D C    L+V C SLE YA LC +  
Sbjct: 5621 PCPPQPLCDLMLSQVFAECHNLVPPGPFFNACISDHCRGR-LEVPCQSLEAYAELCRARG 5679

Query: 610  ICIDWRGRTGHMCPFTCPADKVYQPCGPSNPSYCYGNDSASLGALPEAGPITEGCFCPEG 669
            +C DWRG TG +C  TCP  KVY+PCGP  P+ C   + +     P+   + EGCFCPE 
Sbjct: 5680 VCSDWRGATGGLCDLTCPPTKVYKPCGPIQPATCNSRNQS-----PQLEGMAEGCFCPED 5734

Query: 670  MTLFSTSAQVCVPTGCPRCLGPHGEPVKVGHTVGMDCQECTCEAATWTLTCRPKLCPL-- 727
              LF+    +CV   CP C+GP G P   G     +CQ C C+  + ++ C+P  C    
Sbjct: 5735 QILFNAHMGICV-QACP-CVGPDGFPKFPGERWVSNCQSCVCDEGSVSVQCKPLPCDAQG 5792

Query: 728  -PPACPLPGFVPVPAAPQAGQCCPQYSCACNTSRCPK--PVGCPEGARAIPTYQEGACCP 784
             PP C  PGFV V        CCP+  C CNT+ CP+  PV CP G  +I T +EG CCP
Sbjct: 5793 QPPPCNRPGFVTVTRPRAENPCCPETVCVCNTTTCPQSLPV-CPPGQESICTQEEGDCCP 5851

Query: 785  VQNCSWTVCSINGTLYQPGAVVSSSL-CETCRCELPGGPPSDAFVVSCETQIC-NTHCPV 842
               C   +CS NGT Y  GA    +L C  C C    G   D   V C+   C NT CP 
Sbjct: 5852 TFRCRPQLCSYNGTFYGVGATFPGALPCHMCTC--LSGDTQDP-TVQCQEDACNNTTCPQ 5908

Query: 843  GFEYQEQSGQCCGTCVQVACVTNTSKSPAHLFYPGETWSDAG-NHCVTHQCEKHQDGLVV 901
            GFEY+  +GQCCG CVQ AC+T   + P  L    ETW ++  ++C  + CE  + G+ +
Sbjct: 5909 GFEYKRVAGQCCGECVQTACLTPDGQ-PVQL---NETWVNSHVDNCTVYLCEA-EGGVHL 5963

Query: 902  VTTKKA-CPPLSCSLDEARMSKDGCCRFCPPPPPPYQNQSTCAVYHRSLIIQQQGCSSSE 960
            +T + A CP +S      R  K GCC  C         + +C V   + I+  QGC +  
Sbjct: 5964 LTPQPASCPDVSSCRGSLR--KTGCCYSC--------EEDSCQVRINTTILWHQGCETE- 6012

Query: 961  PVRLAYCRGNCGDSSSMYSLEGNTVEHRCQCCQELRTSLRNVTLHCTDGSSRAFSYTEVE 1020
             V + +C G+C   +S YS E   ++H+C CCQE R     V LHC +GS+   +YT   
Sbjct: 6013 -VNITFCEGSC-PGASKYSAEAQAMQHQCTCCQERRVHEETVPLHCPNGSAILHTYTHAV 6070

Query: 1021 E--CGCMGRRCPAPGDTQHSEEAEPEPSQEAESGSWER 1056
            +  CG +     A G  + + +   +P ++ E+    R
Sbjct: 6071 QVLCGLLAWGLQAGGHIRGAVQDPQQPLKDQEASGKAR 6108



 Score =  167 bits (424), Expect = 4e-41
 Identities = 113/341 (33%), Positives = 158/341 (46%), Gaps = 46/341 (13%)

Query: 45   PVPTTSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQ---PVTSDC 101
            P P++ TT +P +  T+ PG T     TT+T   SKT TS L  S  T +     VT+ C
Sbjct: 4040 PHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPSKTRTSTLLPSSPTSAPITTVVTTGC 4099

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAESHPEVNIE 161
             P CAW++W D  +P PGP GGD +TY+NI  +G  +C +P     L+CRA++ P V + 
Sbjct: 4100 EPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQP---LGLECRAQAQPGVPLR 4156

Query: 162  HLGQVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCPVT-----SVTPYGTS 216
             LGQVV+CS + GLVCRN++Q G FKMC NYE+RV CC     CP T     + TP  T 
Sbjct: 4157 ELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGH-CPSTPATSSTATPSSTP 4215

Query: 217  PTNALYPSLSTSMVSA-SVASTSVASSSVASSSVAYSTQTCFCNVADRLYPAGSTIYRHR 275
             T  +   L+T+  +  S  ST+  SS+  ++ +     T     A    P GST     
Sbjct: 4216 GTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEPST----TATVTVPTGST----- 4266

Query: 276  DLAGHCYYALCSQDCQVVRGVDSDCPSTTLP------PAPATSPSISTSEPVTELGCP-- 327
                       +   Q   G      + T P        P +SP  +T+ P         
Sbjct: 4267 ---------ATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTP 4317

Query: 328  -----NAVPPRKKGETWATPNCSEATCEGNNVISLRPRTCP 363
                  A+P    G TW     S+ T     + +  P + P
Sbjct: 4318 TATSFTAIPSSSLGTTWT--RLSQTTTPTATMSTATPSSTP 4356



 Score =  167 bits (423), Expect = 5e-41
 Identities = 114/342 (33%), Positives = 159/342 (46%), Gaps = 48/342 (14%)

Query: 45   PVPTTSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTS----D 100
            P P++ TT +P +  T+ PG T +   TT+T   SKT TS L  S  T S P+T+     
Sbjct: 2893 PHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPT-SAPITTVVTMG 2951

Query: 101  CHPLCAWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAESHPEVNI 160
            C P CAW++W D  +P PGP GGD +TY+NI  +G  +C +P     L+CRA++ P V +
Sbjct: 2952 CEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQP---LGLECRAQAQPGVPL 3008

Query: 161  EHLGQVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCPVTSVT-----PYGT 215
              LGQVV+CS + GLVCRN++Q G FKMC NYE+RV CC     CP T  T     P  T
Sbjct: 3009 RELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGH-CPSTPATSSTAMPSST 3067

Query: 216  SPTNALYPSLSTSMVSA-SVASTSVASSSVASSSVAYSTQTCFCNVADRLYPAGSTIYRH 274
              T  +   L+T+  +  S  ST+  SS+  ++ +     T     A    P GST    
Sbjct: 3068 PGTTWILTELTTTATTTESTGSTATPSSTPGTTWILTEPST----TATVTVPTGST---- 3119

Query: 275  RDLAGHCYYALCSQDCQVVRGVDSDCPSTTLP------PAPATSPSISTSEPVTELGCP- 327
                        +   Q   G      + T P        P +SP  +T+ P        
Sbjct: 3120 ----------ATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATT 3169

Query: 328  ------NAVPPRKKGETWATPNCSEATCEGNNVISLRPRTCP 363
                   A+P    G TW     S+ T     + +  P + P
Sbjct: 3170 PTATSFTAIPSSSLGTTWT--RLSQTTTPTATMSTATPSSTP 3209



 Score =  164 bits (414), Expect = 5e-40
 Identities = 90/208 (43%), Positives = 122/208 (58%), Gaps = 13/208 (6%)

Query: 45   PVPTTSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQ---PVTSDC 101
            P P++ TT +P +  T+ PG T +   TT+T   SKT TS L  S  T +     VT+ C
Sbjct: 4542 PHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTTGC 4601

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAESHPEVNIE 161
             P CAW++W D  +P PGP GGD +TY+NI  +G  +C +P     L+CRA++ P V + 
Sbjct: 4602 EPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQP---LGLECRAQAQPGVPLG 4658

Query: 162  HLGQVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCPVTSVT-----PYGTS 216
             LGQVV+CS + GLVCRN++Q G FKMC NYE+RV CC     CP T  T     P  T 
Sbjct: 4659 ELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGH-CPSTPATSSTAMPSSTP 4717

Query: 217  PTNALYPSL-STSMVSASVASTSVASSS 243
             T  +   L +T+  +AS  ST+  SS+
Sbjct: 4718 GTTWILTELTTTATTTASTGSTATPSST 4745



 Score =  163 bits (413), Expect = 7e-40
 Identities = 85/209 (40%), Positives = 121/209 (57%), Gaps = 10/209 (4%)

Query: 45   PVPTTSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDCHPL 104
            P  T ST S    +T+  P  T     + + T   +T T+   ++ TT SQ  T  C P 
Sbjct: 2422 PTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPRTETTMSPLTNTTTSQGTTR-CQPK 2480

Query: 105  CAWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAESHPEVNIEHLG 164
            C WT+WFDVDFP+ G  GGD ET+ NI  +G K+C  P+ I   +CRAE++PEV+I+ +G
Sbjct: 2481 CEWTEWFDVDFPTSGVAGGDMETFENIRAAGGKMCWAPKSI---ECRAENYPEVSIDQVG 2537

Query: 165  QVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCPVTSVTPYGTSPTNA---- 220
            QV+ CS E GL C+N+DQ G F MC NY VRVLCC+    CP T  T    +P++     
Sbjct: 2538 QVLTCSLETGLTCKNEDQTGRFNMCFNYNVRVLCCDDYSHCPSTPATSSTATPSSTPGTT 2597

Query: 221  --LYPSLSTSMVSASVASTSVASSSVASS 247
              L    +T+  +AS  ST+  +S++ ++
Sbjct: 2598 WILTKPTTTATTTASTGSTATPTSTLRTA 2626



 Score =  163 bits (413), Expect = 7e-40
 Identities = 86/209 (41%), Positives = 125/209 (59%), Gaps = 10/209 (4%)

Query: 45   PVPTTSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTS----D 100
            P P++ TT +P +  T+ PG T +   TT+T   SKT TS L  S  T S P+T+     
Sbjct: 3395 PHPSSRTTESPPSPGTTTPGHTRATSRTTATATPSKTRTSTLLPSSPT-SAPITTVVTMG 3453

Query: 101  CHPLCAWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAESHPEVNI 160
            C P CAW++W D  +P PGP GGD +TY+NI  +G  +C +P     L+CRA++ P V +
Sbjct: 3454 CEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQP---LGLECRAQAQPGVPL 3510

Query: 161  EHLGQVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCPVTSVTPYGTSPTNA 220
              LGQVV+CS + GLVCRN++Q G FKMC NYE+RV CC     CP T  T    +P++ 
Sbjct: 3511 RELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGH-CPSTPATSSTATPSST 3569

Query: 221  LYPS-LSTSMVSASVASTSVASSSVASSS 248
               + + T   +A+  + +  S+++ SS+
Sbjct: 3570 PGTTWILTEQTTAATTTATTGSTAIPSST 3598



 Score =  140 bits (353), Expect = 6e-33
 Identities = 100/288 (34%), Positives = 142/288 (49%), Gaps = 42/288 (14%)

Query: 20   CSHRQHNLCSYNQNN--LCL-YSQHNLC-------PVPTTSTTSAPTTSTTSGPGTTPSP 69
            C   +  +C+ +Q +  LC  Y    LC       P P   T+  P+ S ++ P   P+P
Sbjct: 2092 CDRMRGLMCANSQQSPPLCHDYELRVLCCEYVPCGPSPAPGTSPQPSLSASTEPAV-PTP 2150

Query: 70   VPTTST-------TP--------VSKTSTSHLSVSKTTHSQPVTSDCHPLCAWTKWFDVD 114
              TT+T       TP         S+T +S   V+  T S P T+ C P C WT+WFD D
Sbjct: 2151 TQTTATEKTTLWVTPSIRSTAALTSQTGSSSGPVT-VTPSAPGTTTCQPRCQWTEWFDED 2209

Query: 115  FPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAESHPEVNIEHLGQVVQCSREEG 174
            +P     GGD E+Y+ I  +G  +C++P++I   +C+AES P   +  +GQ V C    G
Sbjct: 2210 YPKSEQLGGDVESYDKIRAAGGHLCQQPKDI---ECQAESFPNWTLAQVGQKVHCDVHFG 2266

Query: 175  LVCRNQDQQGPFKMCLNYEVRVLCCETP--RG-----CPVTSVTPYGTSPTNALY----P 223
            LVCRN +Q+G FKMC NY +RVLCC     RG      P T +    T+ T AL+    P
Sbjct: 2267 LVCRNWEQEGVFKMCYNYRIRVLCCSDDHCRGRATTPPPTTELETATTTTTQALFSTPQP 2326

Query: 224  SLSTSMVSASVAS-TSVASSSVASSSVAYSTQTCFCNVADRLYPAGST 270
            + S  +  A  AS T+V + S   +S  Y++            PAGST
Sbjct: 2327 TSSPGLTRAPPASTTAVPTLSEGLTSPRYTSTLGTATTGGPTTPAGST 2374



 Score =  109 bits (272), Expect = 2e-23
 Identities = 65/190 (34%), Positives = 100/190 (52%), Gaps = 19/190 (10%)

Query: 72   TTSTTPVSKTSTSHLSVSKTTHSQPVTSDC-HPLCAWTKWFDVDFPSPGPHGGDKETYNN 130
            T +TTP + T T+ +  S T+ + PV++ C   +C W+ W++   P PG  GGD ET+ N
Sbjct: 1998 TPATTPFTFT-TAWVPHSTTSPALPVSTVCVREVCRWSSWYNGHRPEPGLGGGDFETFEN 2056

Query: 131  IIRSGEKICRRPEEITRLQCRAESHPEVNIEHLGQVVQCSREEGLVCRNQDQQGPFKMCL 190
            + + G ++C     +  ++CRA   P++ +E LGQ V C R  GL+C N  Q  P  +C 
Sbjct: 2057 LRQRGYQVC---PVLADIECRAAQLPDMPLEELGQQVDCDRMRGLMCANSQQSPP--LCH 2111

Query: 191  NYEVRVLCCE------------TPRGCPVTSVTPYGTSPTNALYPSLSTSMVSASVASTS 238
            +YE+RVLCCE            +P+     S  P   +PT       +T  V+ S+ ST+
Sbjct: 2112 DYELRVLCCEYVPCGPSPAPGTSPQPSLSASTEPAVPTPTQTTATEKTTLWVTPSIRSTA 2171

Query: 239  VASSSVASSS 248
              +S   SSS
Sbjct: 2172 ALTSQTGSSS 2181



 Score = 94.7 bits (234), Expect = 4e-19
 Identities = 112/482 (23%), Positives = 171/482 (35%), Gaps = 69/482 (14%)

Query: 386  CHHYQCQCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVLVDNYFCGAED 445
            C    C   CS  G  H  T+D   Y    +C+YVL ++       F VL +   CG  D
Sbjct: 1075 CQDLPCPGTCSVQGGAHISTYDEKLYDLHGDCSYVLSKKCAD--SSFTVLAELRKCGLTD 1132

Query: 446  GLSCPRSIILEYHQDRVVLTRKPVHGVMTNEIIFNNKVVSPG---FRKNG---IVVSRIG 499
              +C +++ L        +  +   GV  N I     + +     F  +    +V + +G
Sbjct: 1133 NENCLKAVTLSLDGGDTAIRVQADGGVFLNSIYTQLPLSAANITLFTPSSFFIVVQTGLG 1192

Query: 500  VKMYATIPELGVQVM-------------------------FSGLIFSVEVPFSKFANNTE 534
            +++   +  L +QV                          F+ L   VE   + FAN  +
Sbjct: 1193 LQLLVQLVPL-MQVFVRLDPAHQGQMCGLCGNFNQNQADDFTALSGVVEATGAAFANTWK 1251

Query: 535  GQCXXXXXXXTTPPAPCLPSPI--------CQLIL--SKVFEPCHTVIPPLLFYEGCVFD 584
             Q        +    PC  S          C  +   +  F  CH++I P  F+  C+FD
Sbjct: 1252 AQAACANARNSFED-PCSLSVENENYARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFD 1310

Query: 585  RCHM-TDLDVVCSSLELYAALCASHDICI-DWRGRTGHMCPFTCPADKVYQPCGPSNPSY 642
             C+     D +C++L  Y   CA+  + + DWR          CP  + Y     +    
Sbjct: 1311 TCNCERSEDCLCAALSSYVHACAAKGVQLSDWRDGVCTKYMQNCPKSQRYAYVVDACQPT 1370

Query: 643  CYGNDSASLGALPEAGPITEGCFCPEGMTLFSTSAQVCVPT-GCPRCLGPHGEPVKVGHT 701
            C G   A +       P+ +GC CP G   F   A  CVP   CP C   HG  +  G  
Sbjct: 1371 CRGLSEADVTCSVSFVPV-DGCTCPAG--TFLNDAGACVPAQECP-CYA-HGTVLAPGEV 1425

Query: 702  VGMDCQECTCEAATWTLTCRPKLCPLPPACPLPGFVPVPAAPQAG-------QCCPQYSC 754
            V  +   C+C      L+C          C  P      +   AG       + C     
Sbjct: 1426 VHDEGAVCSCTGG--KLSCLGASLQKSTGCAAPMVYLDCSNSSAGTPGAECLRSCHTLDV 1483

Query: 755  ACNTSRCPKPVGCPEGARAIPTYQEGACCPVQNCSWTVCSINGTLYQPGAVVSSSLCETC 814
             C ++ C     CP G   + +   G C   ++C    C  N   Y+PG  +    C TC
Sbjct: 1484 GCFSTHCVSGCVCPPG---LVSDGSGGCIAEEDCP---CVHNEATYKPGETIRVD-CNTC 1536

Query: 815  RC 816
             C
Sbjct: 1537 TC 1538



 Score = 92.8 bits (229), Expect = 2e-18
 Identities = 94/377 (24%), Positives = 140/377 (37%), Gaps = 69/377 (18%)

Query: 394 VCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVLVDNYFCGAEDGLSCPRSI 453
           VCS WG  HY TFDG  + F   C YV  +     Y  F + +      A   LS    +
Sbjct: 80  VCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQESAAPTLS---RV 136

Query: 454 ILEYHQDRVVLTRKPVHGVMTNEIIFNNKVVSPGFRKNGIVVSRIGVKMYATIP-ELGVQ 512
           +++     + LT+          ++ N   V   F ++G+++ +     Y  +   LG+ 
Sbjct: 137 LMKVDGVVIQLTK--------GSVLVNGHPVLLPFSQSGVLIQQSS--SYTKVEARLGLV 186

Query: 513 VMFS---GLIFSVEVPFSKFANNTEGQCXXXXXXXTT----------------------- 546
           +M++    L+  ++   +K+AN T G C                                
Sbjct: 187 LMWNHDDSLLLELD---TKYANKTCGLCGDFNGMPVVSELLSHNTKLTPMEFGNLQKMDD 243

Query: 547 PPAPC---LPSP---------ICQLIL-SKVFEPCHTVIPPLLFYEGCVFDRCHMTDLDV 593
           P   C   +P P         IC+ +L  ++F  C  ++    + E C  D C   D D+
Sbjct: 244 PTEQCQDPVPEPPRNCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDL 303

Query: 594 ---VCSSLELYAALCA-SHDICIDWRGRTGHMCPFTCPADKVYQPCGPSNPSYCYGNDSA 649
              VC +L  Y+  C  +  +  DWRG     CP  CP +  Y  C       C  N   
Sbjct: 304 LSCVCHTLAEYSRQCTHAGGLPQDWRGPD--FCPQKCPNNMQYHECRSPCADTC-SNQEH 360

Query: 650 SLGALPEAGPITEGCFCPEGMTLFSTSAQVCVPTGCPRCLGPHGEPVKVGHTVGMDCQEC 709
           S            GCFCPEG  L       CVP     C+  +G     G T   DC  C
Sbjct: 361 SRACEDHC---VAGCFCPEGTVLDDIGQTGCVPVSKCACV-YNGAAYAPGATYSTDCTNC 416

Query: 710 TCEAATWTLTCRPKLCP 726
           TC    W  +C+   CP
Sbjct: 417 TCSGGRW--SCQEVPCP 431



 Score = 88.6 bits (218), Expect = 3e-17
 Identities = 90/373 (24%), Positives = 133/373 (35%), Gaps = 63/373 (16%)

Query: 394  VCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVLVDNYFCGAEDGLSCPRSI 453
            VCS WGD HY TFDG  + F   C YV  +       H R   +++      GL   R +
Sbjct: 732  VCSTWGDFHYKTFDGDVFRFPGLCNYVFSE-------HCRAAYEDFNVQLRRGLVGSRPV 784

Query: 454  ILEYHQDRVVLTRKPVHGVMTNEIIFNNKVVSPGFRKNGIVVSRIGVKMYATIPELGVQV 513
            +       V+  +  V       ++ N +     + + G++V + G  +  +I  L +  
Sbjct: 785  VTRV----VIKAQGLVLEASNGSVLINGQREELPYSRTGLLVEQSGDYIKVSI-RLVLTF 839

Query: 514  MFSGLIFSVEVPFSKFANNTEGQCXXXXXXXT-----------TP-----------PAPC 551
            +++G   ++     K+AN T G C                   TP           P   
Sbjct: 840  LWNGEDSALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLTPLQFGNLQKLDGPTEQ 899

Query: 552  LPSP-------------IC-QLILSKVFEPCHTVIPPLLFYEGCVFDRCHMTDLDVVCSS 597
             P P             IC + +L   F  CH ++    +   C  D C        C++
Sbjct: 900  CPDPLPLPAGNCTDEEGICHRTLLGPAFAECHALVDSTAYLAACAQDLCRCPTCP--CAT 957

Query: 598  LELYAALCASHDICIDWRGRTGHMCPFTCPADKVYQPCGPSNPSYCYGNDSASLGALPEA 657
               Y+  CA H        R   +CP TCP +  +Q CG      C     A L      
Sbjct: 958  FVEYSRQCA-HAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSNPQRAQLC----E 1012

Query: 658  GPITEGCFCPEGMT---LFSTSAQVCVPTG-CPRCLGPHGEPVKVGHTVGMDCQECTCEA 713
                +GCFCP G +   L   +   C+P G CP   G  G     G +    C  CTC  
Sbjct: 1013 DHCVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHG--GRTYSPGTSFNTTCSSCTCSG 1070

Query: 714  ATWTLTCRPKLCP 726
              W   C+   CP
Sbjct: 1071 GLW--QCQDLPCP 1081



 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 52/187 (27%), Positives = 68/187 (36%), Gaps = 30/187 (16%)

Query: 547  PPAPCLPSPI--------CQLILSKVFEPCHTVIPPLLFYEGCVFDRCHMT---DLDVVC 595
            P  PC  +P         C ++    F  C + +    +YE CV D C      D +  C
Sbjct: 1760 PKDPCTANPFRKSWAQKQCSILHGPTFAACRSQVDSTKYYEACVNDACACDSGGDCECFC 1819

Query: 596  SSLELYAALCASHDICIDWRGRTGHMCPFTCP-------ADKVYQPCGPSNPSYCYGNDS 648
            +++  YA  C    +C+ W  RT   CP  C         +  YQPCG      C     
Sbjct: 1820 TAVAAYAQACHDAGLCVSW--RTPDTCPLFCDFYNPHGGCEWHYQPCGAPCLKTCRNPSG 1877

Query: 649  ASLGALPEAGPITEGCF--CPEGMTLFSTSAQVCVPTGCPRCLGPHGEPVKVGHTV--GM 704
              L  LP      EGC+  CP     F+     CV   C  C    G    VG  V    
Sbjct: 1878 HCLVDLPG----LEGCYPKCPPSQPFFNEDQMKCV-AQC-GCYDKDGNYYDVGARVPTAE 1931

Query: 705  DCQECTC 711
            +CQ C C
Sbjct: 1932 NCQSCNC 1938



 Score = 60.8 bits (146), Expect = 6e-09
 Identities = 73/303 (24%), Positives = 109/303 (35%), Gaps = 37/303 (12%)

Query: 167  VQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRG-------CPVTSVTPYGTSPTN 219
            VQ S     VC    Q  P      Y V   C  T RG       C V+ V   G +   
Sbjct: 1337 VQLSDWRDGVCTKYMQNCPKSQRYAYVVDA-CQPTCRGLSEADVTCSVSFVPVDGCTCPA 1395

Query: 220  ALYPSLSTSMVSASVASTSVASSSVASSSVAYSTQTCFCNVADRLYPAGSTIYRHRDLAG 279
              + + + + V A         + +A   V +           +L   G+++ +    A 
Sbjct: 1396 GTFLNDAGACVPAQECPCYAHGTVLAPGEVVHDEGAVCSCTGGKLSCLGASLQKSTGCAA 1455

Query: 280  HCYYALCSQDCQVVRGVDSDCPSTTLPPAPATSPSISTSEPVTELGCPNAVPPRKKGETW 339
               Y  CS       G +      TL     ++  +S         CP  +     G   
Sbjct: 1456 PMVYLDCSNSSAGTPGAECLRSCHTLDVGCFSTHCVSGCV------CPPGLVSDGSGGCI 1509

Query: 340  ATPNC----SEATCEGNNVISLRPRTCPRVEKPTCANGYPAVKVADQDGCCHHYQCQCVC 395
            A  +C    +EAT +    I +   TC      TC N         +   C H  C   C
Sbjct: 1510 AEEDCPCVHNEATYKPGETIRVDCNTC------TCRN---------RRWECSHRLCLGTC 1554

Query: 396  SGWGDPHYITFDGTYYTFLDNCTYVLVQQIV---PVYGHFRVLVDNYFCGAEDGLSCPRS 452
              +GD H+ITFDG  Y+F  +C Y+L Q        +G FR++ +N  CG   G +C ++
Sbjct: 1555 VAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNTTHGTFRIVTENIPCGT-TGTTCSKA 1613

Query: 453  IIL 455
            I L
Sbjct: 1614 IKL 1616



 Score = 50.4 bits (119), Expect = 9e-06
 Identities = 30/92 (32%), Positives = 41/92 (44%), Gaps = 2/92 (2%)

Query: 386 CHHYQCQCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVLVDNYFCGAED 445
           C    C   CS  G  H+ TFDG  YT   +C+YVL +        F VL +   CG  D
Sbjct: 425 CQEVPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDS--SAFTVLAELRRCGLTD 482

Query: 446 GLSCPRSIILEYHQDRVVLTRKPVHGVMTNEI 477
             +C +S+ L     + V+  K    V  N+I
Sbjct: 483 SETCLKSVTLSLDGAQTVVVIKASGEVFLNQI 514



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 46/146 (31%), Positives = 54/146 (36%), Gaps = 17/146 (11%)

Query: 698 VGHTVGMDCQECTCEAATWTLTCRPKLCPLPPACPLPGFVPVPAAPQAGQCCPQ-YSCAC 756
           V HT+    ++CT           P  CP    CP         +P A  C  Q +S AC
Sbjct: 307 VCHTLAEYSRQCTHAGGLPQDWRGPDFCP--QKCPNNMQYHECRSPCADTCSNQEHSRAC 364

Query: 757 NTSRCPKPVGCPEGARAIPTYQEGACCPVQNCSWTVCSINGTLYQPGAVVSSSLCETCRC 816
               C     CPEG       Q G C PV  C+   C  NG  Y PGA  S+  C  C C
Sbjct: 365 E-DHCVAGCFCPEGTVLDDIGQTG-CVPVSKCA---CVYNGAAYAPGATYSTD-CTNCTC 418

Query: 817 ELPGGPPSDAFVVSCETQICNTHCPV 842
              GG        SC+   C   C V
Sbjct: 419 S--GGR------WSCQEVPCPGTCSV 436



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 26/82 (31%), Positives = 36/82 (43%), Gaps = 6/82 (7%)

Query: 250  AYSTQTCFCNVADRLYPAGSTIYRHRDLAGHCYYALCSQDCQVVRGVDSDCPSTTLPPAP 309
            A+S + C C   DR Y     IY   D  G C  A+C  +  ++R   + CP T     P
Sbjct: 1946 AHSLEACTCTYEDRTYSYQDVIYNTTDGLGACLIAICGSNGTIIRKAVA-CPGT-----P 1999

Query: 310  ATSPSISTSEPVTELGCPNAVP 331
            AT+P   T+  V       A+P
Sbjct: 2000 ATTPFTFTTAWVPHSTTSPALP 2021



 Score = 38.9 bits (89), Expect = 0.026
 Identities = 25/65 (38%), Positives = 31/65 (47%), Gaps = 9/65 (13%)

Query: 663  GCFCPEGMTLFSTSAQVCVPT-GCPRCLGPHGEPV-KVGHTVGMDCQECTCEAATWTLTC 720
            GC CP G  L S  +  C+    CP C+  H E   K G T+ +DC  CTC    W   C
Sbjct: 1493 GCVCPPG--LVSDGSGGCIAEEDCP-CV--HNEATYKPGETIRVDCNTCTCRNRRW--EC 1545

Query: 721  RPKLC 725
              +LC
Sbjct: 1546 SHRLC 1550



 Score = 38.5 bits (88), Expect = 0.034
 Identities = 25/55 (45%), Positives = 32/55 (58%), Gaps = 5/55 (9%)

Query: 48   TTSTTSAPTTSTTSGPGTTPSP-VPTTSTTPVS----KTSTSHLSVSKTTHSQPV 97
            TT TT   T + +S PGTT +P V TT+TT V+     T +S    S TTH+ PV
Sbjct: 3276 TTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTTHTPPV 3330



 Score = 37.7 bits (86), Expect = 0.058
 Identities = 27/58 (46%), Positives = 34/58 (58%), Gaps = 10/58 (17%)

Query: 50   STTSAPTTS-----TTSGPGTTPSP-VPTTSTTPVS----KTSTSHLSVSKTTHSQPV 97
            STT+ PTTS      +S PGTT +P V TT+TT V+     T +S    S TTH+ PV
Sbjct: 4420 STTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTTHTPPV 4477



 Score = 37.7 bits (86), Expect = 0.058
 Identities = 26/53 (49%), Positives = 33/53 (62%), Gaps = 5/53 (9%)

Query: 46   VPTTSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHL-SVSKTTHSQPV 97
            VPTT+TT   T + +S PGT  +P PT  TTP+S  ST H  S  +TTH+  V
Sbjct: 5066 VPTTTTTGF-TATPSSSPGTALTP-PT--TTPMSTMSTIHTSSTPETTHTSTV 5114



 Score = 37.0 bits (84), Expect = 0.099
 Identities = 27/91 (29%), Positives = 40/91 (43%), Gaps = 18/91 (19%)

Query: 26   NLC-SYNQNNLCLYSQHNLCP-VPTTSTTSAP---------------TTSTTSGPGTTPS 68
            N+C +YN   LC    ++ CP  P TS+T+ P               T +TT+  G+T +
Sbjct: 2560 NMCFNYNVRVLCC-DDYSHCPSTPATSSTATPSSTPGTTWILTKPTTTATTTASTGSTAT 2618

Query: 69   PVPTTSTTPVSKTSTSHLSVSKTTHSQPVTS 99
            P  T  T P  K  T+  +    T S+   S
Sbjct: 2619 PTSTLRTAPPPKVLTTTATTPTVTSSKATPS 2649



 Score = 35.8 bits (81), Expect = 0.22
 Identities = 23/60 (38%), Positives = 31/60 (51%), Gaps = 10/60 (16%)

Query: 48   TTSTTSAPTTSTT-------SGPGTTPSP---VPTTSTTPVSKTSTSHLSVSKTTHSQPV 97
            T  TT  PTT+TT       S PGT  +P   + TT+T   S ++ +  SV  TTH+  V
Sbjct: 4387 TAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVPGTTHTPTV 4446



 Score = 35.4 bits (80), Expect = 0.29
 Identities = 29/113 (25%), Positives = 44/113 (38%), Gaps = 20/113 (17%)

Query: 758  TSRCPKPVGCPEGARAIPTYQEGACC-PVQNCSWTVCS--INGTLYQPGAVVSSSLCETC 814
            T +CP P+  P G     T +EG C   +   ++  C   ++ T Y          C TC
Sbjct: 897  TEQCPDPLPLPAGNC---TDEEGICHRTLLGPAFAECHALVDSTAYLAACAQDLCRCPTC 953

Query: 815  ----------RCELPGGPPSDAFVVSCETQICNTHCPVGFEYQEQSGQCCGTC 857
                      +C   GG P +     C  ++C   CP+  ++QE    C  TC
Sbjct: 954  PCATFVEYSRQCAHAGGQPRNW---RCP-ELCPRTCPLNMQHQECGSPCTDTC 1002



 Score = 35.4 bits (80), Expect = 0.29
 Identities = 25/60 (41%), Positives = 33/60 (55%), Gaps = 10/60 (16%)

Query: 48   TTSTTSAPTTSTT-------SGPGT--TPSPVPTTSTTPVSKTST-SHLSVSKTTHSQPV 97
            T  TT  PTT+TT       S PGT  TP    +T+TTP ++ ST +  S+  TTH+  V
Sbjct: 2738 TAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATV 2797



 Score = 35.4 bits (80), Expect = 0.29
 Identities = 25/60 (41%), Positives = 33/60 (55%), Gaps = 10/60 (16%)

Query: 48   TTSTTSAPTTSTT-------SGPGT--TPSPVPTTSTTPVSKTST-SHLSVSKTTHSQPV 97
            T  TT  PTT+TT       S PGT  TP    +T+TTP ++ ST +  S+  TTH+  V
Sbjct: 3885 TAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATV 3944



 Score = 35.4 bits (80), Expect = 0.29
 Identities = 22/57 (38%), Positives = 31/57 (54%), Gaps = 4/57 (7%)

Query: 45   PVPTTSTTSAPTTSTTSGPGTT---PSPVPTTSTTPVSKTSTSH-LSVSKTTHSQPV 97
            PV T++ T +  TS T  P +T      +P  +TTPV+  ST H  S  +TTH+  V
Sbjct: 4782 PVLTSTATKSTATSVTPIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTV 4838



 Score = 34.7 bits (78), Expect = 0.49
 Identities = 27/65 (41%), Positives = 35/65 (53%), Gaps = 10/65 (15%)

Query: 43   LCPVPTTSTTSAPTT-----STTSGPGTT-PSPVPTTSTTPVS----KTSTSHLSVSKTT 92
            L P    STT+ PTT     + +S PGTT  + V TT+TT V+     T +S    S TT
Sbjct: 2764 LTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTT 2823

Query: 93   HSQPV 97
            H+ PV
Sbjct: 2824 HTPPV 2828



 Score = 34.7 bits (78), Expect = 0.49
 Identities = 27/65 (41%), Positives = 35/65 (53%), Gaps = 10/65 (15%)

Query: 43   LCPVPTTSTTSAPTT-----STTSGPGTT-PSPVPTTSTTPVS----KTSTSHLSVSKTT 92
            L P    STT+ PTT     + +S PGTT  + V TT+TT V+     T +S    S TT
Sbjct: 3911 LTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTT 3970

Query: 93   HSQPV 97
            H+ PV
Sbjct: 3971 HTPPV 3975



 Score = 34.3 bits (77), Expect = 0.64
 Identities = 22/60 (36%), Positives = 28/60 (46%), Gaps = 3/60 (5%)

Query: 49   TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDCHPLCAWT 108
            T  T+A TT+ T+G    PS  P T+  P   TST   + + T  S   TS   P  A T
Sbjct: 3577 TEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTST---ATTPTATSSKATSSSSPRTATT 3633



 Score = 33.9 bits (76), Expect = 0.84
 Identities = 25/70 (35%), Positives = 36/70 (51%), Gaps = 15/70 (21%)

Query: 48   TTSTTSAPTTSTT-------SGPGTTPSP--VPTTSTTPVSKTSTSHLSVSKTTHSQPVT 98
            T  TT+A TT+TT       S PGT P P  + +T+TTP + +S +      T+ S P T
Sbjct: 3577 TEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATTPTATSSKA------TSSSSPRT 3630

Query: 99   SDCHPLCAWT 108
            +   P+   T
Sbjct: 3631 ATTLPVLTST 3640



 Score = 33.5 bits (75), Expect = 1.1
 Identities = 73/343 (21%), Positives = 113/343 (32%), Gaps = 58/343 (16%)

Query: 43   LCPVPTTSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDCH 102
            L  + TT+TT+A T ST + P +TP   P         T+ +  S   T+ S P T+   
Sbjct: 4723 LTELTTTATTTASTGSTAT-PSSTPGTAPPPKVLTSPATTPTATSSKATSSSSPRTATTL 4781

Query: 103  PLCAWTKWFDVD---FPSPGPHGGDKETYNNIIRSGEKICRRPEEITR-LQCRAESHPEV 158
            P+   T          P P    G   T              PE+ T  +   +  HP  
Sbjct: 4782 PVLTSTATKSTATSVTPIPSSTLGTTGTL-------------PEQTTTPVATMSTIHPSS 4828

Query: 159  NIE--HLGQVV--QCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCPVTSVTPYG 214
              E  H   V+  + +        +     P    +  E+      T    P  + TP  
Sbjct: 4829 TPETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATGP--TATPSS 4886

Query: 215  TSPTNALYPSL-STSMVSASVASTSVASSSVASSSVAYSTQTCFCNVADRLYPAGSTIYR 273
            T  T  +   L +T+  +AS  ST+  SS+  ++ +     T     A    P GST   
Sbjct: 4887 TPGTTWILTELTTTATTTASTGSTATPSSTPGTTWILTEPST----TATVTVPTGST--- 4939

Query: 274  HRDLAGHCYYALCSQDCQVVRGVDSDCPSTTLP------PAPATSPSISTSEPVTELGCP 327
                         +   Q   G      + T P        P++SP  +T+ P       
Sbjct: 4940 -----------ATASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGTATALPALRSTAT 4988

Query: 328  -------NAVPPRKKGETWATPNCSEATCEGNNVISLRPRTCP 363
                    A+P    G TW     S+ T     + +  P + P
Sbjct: 4989 TPTATSFTAIPSSSLGTTWT--RLSQTTTPTATMSTATPSSTP 5029



 Score = 32.7 bits (73), Expect = 1.9
 Identities = 23/58 (39%), Positives = 33/58 (56%), Gaps = 6/58 (10%)

Query: 45   PVPTTSTTSAPTTSTTSGP----GTTPSPVPTTSTTPVSKTSTSH-LSVSKTTHSQPV 97
            PV T++ T +  TS T  P    GTT + +P  +TTP++  ST H  S  +TTH+  V
Sbjct: 3635 PVLTSTATKSTATSFTPIPSFTLGTTGT-LPEQTTTPMATMSTIHPSSTPETTHTSTV 3691



 Score = 32.0 bits (71), Expect = 3.2
 Identities = 22/62 (35%), Positives = 33/62 (53%), Gaps = 11/62 (17%)

Query: 47   PTTSTTSAPTTSTTSGPGTTPSPVP----------TTSTTPVSKTST-SHLSVSKTTHSQ 95
            P T+ T+   T+TT+G   TPS  P          +T+TTP ++ ST +  S+  TTH+ 
Sbjct: 3238 PGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTPTTRGSTVTPSSIPGTTHTP 3297

Query: 96   PV 97
             V
Sbjct: 3298 TV 3299



 Score = 31.6 bits (70), Expect = 4.2
 Identities = 34/117 (29%), Positives = 48/117 (41%), Gaps = 24/117 (20%)

Query: 13   SWNYSQPCSHRQH----NLC-SYNQNNLCLYSQHNLCP-VPTTSTTSAP----------- 55
            S ++   C +R+      +C +Y     C    H  CP  P TS+T+ P           
Sbjct: 4667 SLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGH--CPSTPATSSTAMPSSTPGTTWILT 4724

Query: 56   ---TT-STTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDCHPLCAWT 108
               TT +TT+  G+T +P  T  T P  K  TS  + + T  S   TS   P  A T
Sbjct: 4725 ELTTTATTTASTGSTATPSSTPGTAPPPKVLTSP-ATTPTATSSKATSSSSPRTATT 4780



 Score = 31.2 bits (69), Expect = 5.4
 Identities = 19/54 (35%), Positives = 26/54 (48%), Gaps = 10/54 (18%)

Query: 49   TSTTSAPTTSTTSGPGTTPSPVP----------TTSTTPVSKTSTSHLSVSKTT 92
            T  T+A TT+  +GP  TPS  P          TT+T  V   ST+  S ++ T
Sbjct: 3719 TELTTAATTTAATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRAT 3772



 Score = 31.2 bits (69), Expect = 5.4
 Identities = 28/82 (34%), Positives = 37/82 (45%), Gaps = 5/82 (6%)

Query: 43   LCPVPTTSTTSAPTTST---TSGPGTT--PSPVPTTSTTPVSKTSTSHLSVSKTTHSQPV 97
            L  + TT+TT+  T ST   +S PGTT   +   TT+T  V   ST+  S ++ T   P 
Sbjct: 4221 LTKLTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPH 4280

Query: 98   TSDCHPLCAWTKWFDVDFPSPG 119
             S        T      F SPG
Sbjct: 4281 VSTTATTPTVTSSKATPFSSPG 4302



 Score = 30.8 bits (68), Expect = 7.1
 Identities = 21/57 (36%), Positives = 27/57 (47%), Gaps = 2/57 (3%)

Query: 48   TTSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDCHPL 104
            T  TT+A TT  T    T  S   T  TT V  T+T+  +V  T  S P T+   P+
Sbjct: 4363 TVLTTTATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTV--TPSSSPGTARTPPV 4417



 Score = 30.4 bits (67), Expect = 9.3
 Identities = 17/44 (38%), Positives = 25/44 (56%), Gaps = 5/44 (11%)

Query: 46   VPTTSTTSAPTTSTTSGPGTTPS-----PVPTTSTTPVSKTSTS 84
            V TT+TT+   T + + P +TP       VPTT+TT  + T +S
Sbjct: 3862 VLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSS 3905



 Score = 30.4 bits (67), Expect = 9.3
 Identities = 21/65 (32%), Positives = 32/65 (49%), Gaps = 11/65 (16%)

Query: 46   VPTTSTTSAPTTSTTSGPGTTPS-----PVPTTSTTPVSKTSTSHLSVSKT------THS 94
            V TT+ T+   T + + P +TP       VPTT+TT  + T +S    ++T      T +
Sbjct: 4364 VLTTTATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTT 4423

Query: 95   QPVTS 99
             P TS
Sbjct: 4424 TPTTS 4428


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score =  537 bits (1383), Expect = e-152
 Identities = 341/1075 (31%), Positives = 475/1075 (44%), Gaps = 96/1075 (8%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 4119 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 4176

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAESHPEVNIE 161
             P+   T       P+    G    T    I         PE  T    R+ S P     
Sbjct: 4177 -PITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTEST 4235

Query: 162  HLGQVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCET--PRGCPVTSVTPYGTS-PT 218
             L   +  + E            P      + +      T  P G P    T   +S PT
Sbjct: 4236 TLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPT 4295

Query: 219  NALYPSLSTSMVSASVASTSVASSSVASSSVAYSTQTCFCNVA-DRLYPAGSTIYRHRDL 277
             +   + +TS  + +    S  S    +    Y +    C V  D  Y  G  +Y +   
Sbjct: 4296 PSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVY-NGTY 4354

Query: 278  AGHCYYALCSQDCQVVRGVDSDCPSTTLP-PAPATS------PSISTSEPVTELG---CP 327
               CY+  CS  C  +   +  CPST  P P P+ S      PS + S+P        CP
Sbjct: 4355 GDTCYFVNCSLSC-TLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECP 4413

Query: 328  NAVPPRKKGETWATPNCSEATCEGNNVISLRPRTCPRVEKPTCANGYPAVKVADQDGCCH 387
            +  PPR++ ETW   +C  ATC+ NN + +    C     PTC+NG   V+V D DGCC 
Sbjct: 4414 DFDPPRQENETWWLCDCFMATCKYNNTVEIVKVECEPPPMPTCSNGLQPVRVEDPDGCCW 4473

Query: 388  HYQCQCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVLVDNYFCGAEDGL 447
            H++C C C+GWGDPHY+TFDG YY++  NCTYVLV++I P   +F V +DNY C   D +
Sbjct: 4474 HWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKV 4533

Query: 448  SCPRSIILEYHQDRVVLTRKPVHGV-MTNEIIFNNKVVSPGFRKNGIVVSRIGVKMYATI 506
            SCPR++I+ +    V++  K VH + M  ++  N + V+  ++K G+ V + G+     I
Sbjct: 4534 SCPRTLIVRHETQEVLI--KTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDI 4591

Query: 507  PELGVQVMFSGLIFSVEVPFSKFA-----------NNTEGQCXXXXXXX----------- 544
            PELGV V ++GL FSV +P+ +F            N T   C                  
Sbjct: 4592 PELGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQW 4651

Query: 545  -----------------------------TTPPAPCLPSPICQLILSKVFEPCHTVIPPL 575
                                         TTP   C PSP+CQLI   +F  CH ++PP 
Sbjct: 4652 LVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQ 4711

Query: 576  LFYEGCVFDRCHMTDLDVVCSSLELYAALCASHDICIDWRGRTGHMCPFTCPADKVYQPC 635
             +Y+ CVFD C M    + C+SL+ YAALCA  +IC+DWR  T   C   CP+ + YQ C
Sbjct: 4712 HYYDACVFDSCFMPGSSLECASLQAYAALCAQQNICLDWRNHTHGACLVECPSHREYQAC 4771

Query: 636  GPSNPSYCYGNDSASLGALPEAGPITEGCFCPEGMTLFSTSAQVCVPTGCPRCLGPHGEP 695
            GP+    C  + S     +     + EGCFCPEG   ++    VCV T C  C+GP   P
Sbjct: 4772 GPAEEPTCKSSSSQQNNTV-----LVEGCFCPEGTMNYAPGFDVCVKT-C-GCVGPDNVP 4824

Query: 696  VKVGHTVGMDCQECTCEAATWTLTCRPKLCPLPPA--CPLPGFVPVPAAPQAGQCCPQYS 753
             + G     DC+ C C      + C+PK C   P   C   G         A  CC    
Sbjct: 4825 REFGEHFEFDCKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTCCNITV 4884

Query: 754  CACNTSRC-PKPVGCPEGARAIPTYQEGACCPVQNC-SWTVCSINGTLYQPGAVVSSSLC 811
            C CNTS C  KP  CP G         G CCP   C S  VC      YQPG+ V SS C
Sbjct: 4885 CKCNTSLCKEKPSVCPLGFEVKSKMVPGRCCPFYWCESKGVCVHGNAEYQPGSPVYSSKC 4944

Query: 812  ETCRCELPGGPPSDAFVVSCETQICNTHCPVGFEYQEQSGQCCGTCVQVACVTNTSKSPA 871
            + C C       +   V++C    CNT C  GFE  E  G+CC  C Q  C+     +  
Sbjct: 4945 QDCVCTDKVDNNTLLNVIACTHVPCNTSCSPGFELMEAPGECCKKCEQTHCIIKRPDNQH 5004

Query: 872  HLFYPGETWSDAGNHCVTHQCEKHQDGLVVVTTKKACPPLSCSL---DEARMSKDGCCRF 928
             +  PG+  SD  N+C    C K  + L+   +   CP    S+          +GCC+ 
Sbjct: 5005 VILKPGDFKSDPKNNCTFFSCVKIHNQLISSVSNITCPNFDASICIPGSITFMPNGCCKT 5064

Query: 929  CPPPPPPYQNQSTCAVYHRSLIIQQQGCSSSEPVRLAYCRGNCGDSSSMYSLEGNTVEHR 988
            C    P  + +  C+    +  +   GC+ +  V + +C G+CG +  MYS +   ++H 
Sbjct: 5065 C---TPRNETRVPCSTVPVTTEVSYAGCTKT--VLMNHCSGSCG-TFVMYSAKAQALDHS 5118

Query: 989  CQCCQELRTSLRNVTLHCTDGSSRAFSYTEVEECGCMGRRCPAPGDTQHSEEAEP 1043
            C CC+E +TS R V L C +G S   +YT +E C C    C  P  T       P
Sbjct: 5119 CSCCKEEKTSQREVVLSCPNGGSLTHTYTHIESCQCQDTVCGLPTGTSRRARRSP 5173



 Score =  117 bits (292), Expect = 8e-26
 Identities = 77/242 (31%), Positives = 107/242 (44%), Gaps = 43/242 (17%)

Query: 45   PVPTTSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKT-----STSHLSVSKTTHSQPV-- 97
            P PTT+ +S  TT+TT    TTPSP PTT TTP   T     +T+  ++  TT S P+  
Sbjct: 1699 PSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTT 1758

Query: 98   --------------------TSDCHPLCAWTKWFDVDFPSPGPHGGDKETYNNIIRSGEK 137
                                T+ C PLC WT W D   P+    GGD E   ++      
Sbjct: 1759 TPLPPSITPPTFSPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGGDTELIGDVC----- 1813

Query: 138  ICRRPEEITRLQCRAESHPEVNIEHLGQVVQCSREEGLVCRNQDQQG----PFKMCLNYE 193
                P     + CRA  +P+V I  LGQ V C    GL+C+N+DQ+     P   CLNYE
Sbjct: 1814 ---GPGWAANISCRATMYPDVPIGQLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYE 1870

Query: 194  VRVLCCETPRGCPVTSVTPYGTSPTNALYPSLSTSMVSASVASTSVASSSVASSSVAYST 253
            + V CCE    C     T   T+  N   P+ +    + +V  T   + +   ++   +T
Sbjct: 1871 INVQCCE----CVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 1926

Query: 254  QT 255
             T
Sbjct: 1927 TT 1928



 Score =  115 bits (288), Expect = 2e-25
 Identities = 95/345 (27%), Positives = 146/345 (42%), Gaps = 52/345 (15%)

Query: 42   NLCPVPTTSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            N+C + T  +T   TT TT    TTP+   TT+TT    +ST   +  K           
Sbjct: 1254 NICSITTRPSTL--TTFTTITLPTTPTTFTTTTTTTTPTSSTVLSTTPKLC--------- 1302

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAESHPEVNIE 161
               C W+ W + D PS G   GD+ET++ +       C  PE+I   +CR+   P +++E
Sbjct: 1303 ---CLWSDWINEDHPSSGSDDGDRETFDGV-------CGAPEDI---ECRSVKDPHLSLE 1349

Query: 162  HLGQVVQCSREEGLVCRNQDQ--QGPFKMCLNYEVRVLCCETPRGC------PVTSVTPY 213
             LGQ VQC    G +C+N+DQ   GPF +C +Y++RV CC     C      P T+ +P 
Sbjct: 1350 QLGQKVQCDVSVGFICKNEDQFGNGPFGLCYDYKIRVNCCWPMDKCITTPSPPTTTPSPP 1409

Query: 214  GTSPTNALYPSLSTSMVSASVAS---TSVASSSVASSSVAYSTQTCFCNVADRLYPAGST 270
             TS T  L P+ + S  + +  +   T+  S  + +++    T T    ++    P  +T
Sbjct: 1410 PTS-TTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTT 1468

Query: 271  IYRHRDLAGHCYYALCSQDCQVVRGVDSDCPSTTLPPAPATSPSISTSEPVTELGCPNAV 330
                         +  +          S   +TT  P P T+PS  T+ P+T       +
Sbjct: 1469 T-----------PSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTL 1517

Query: 331  PPRKKGETWATPNCSEATCEGNNVISLRPRTCPRVEKPTCANGYP 375
            PP     T  +P  +  T          P T P +  PT     P
Sbjct: 1518 PP----TTTPSPPTTTTTTPPPTTTPSPPTTTP-ITPPTSTTTLP 1557



 Score =  110 bits (276), Expect = 5e-24
 Identities = 126/536 (23%), Positives = 194/536 (36%), Gaps = 97/536 (18%)

Query: 256  CFCNVADRLYPAGSTIYRHRDLAGHCYYALCSQDCQVVRGVDSDCPSTTLPPAPATSPSI 315
            C C        AG  + R  +    C        C+ +R +   C +  +    +   ++
Sbjct: 718  CSCYHRGLYLEAGDVVVRQEE---RCVCRDGRLHCRQIRLIGQSCTAPKIHMDCSNLTAL 774

Query: 316  STSEPVTELGCPNAVPPRKKGETWATPNCSEATCEGNNVISLRPRTCPRVEKPTCANGYP 375
            +TS+P   L C          E  +   C +   +      +  + CP V      +   
Sbjct: 775  ATSKP-RALSCQTLAAGYYHTECVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGA 833

Query: 376  AVKVADQDGC--------CHHYQCQCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIV- 426
             +KV D + C        C    C   CS +G  HYITFDG YY F  +C+YV VQ    
Sbjct: 834  KIKV-DCNTCTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCG 892

Query: 427  --PVYGHFRVLVDNYFCGAEDGLSCPRSIILEY--------HQDRVVLTRKPVHGVM-TN 475
                 G F ++ +N  CG   G++C ++I +           + RVV+ R   H V  T 
Sbjct: 893  QNSSLGSFSIITENVPCGTT-GVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYTT 951

Query: 476  EIIFNNKVVSPGFRKNGIVVSRIGVKMYATIPELGVQVMFSGLIFSVEVPFSKFANN--- 532
              +    VV       GI+V    +    T   + +   + G +  +   F   +NN   
Sbjct: 952  REVGQYLVVESS---TGIIV----IWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFT 1004

Query: 533  --------------TEGQCXXXXXXXTTPPAPCLPSPI--------CQLILSKVFEPCHT 570
                             +        +T P PC  +P         C ++ S VF  CH+
Sbjct: 1005 TRDHMVVSSELDFGNSWKEAPTCPDVSTNPEPCSLNPHRRSWAEKQCSILKSSVFSICHS 1064

Query: 571  VIPPLLFYEGCVFDRCHMT---DLDVVCSSLELYAALCASHDICIDWRGRTGHMCPFTC- 626
             + P  FYE CV D C      D +  CS++  YA  C     C+ W  RT  +CP  C 
Sbjct: 1065 KVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACVFW--RTPDLCPIFCD 1122

Query: 627  ------PADKVYQPCGPSNPSYC------YGNDSASLGALPEAGPITEGCF--CPEGMTL 672
                    +  Y+PCG  +   C      + N S S           EGC+  CP+   +
Sbjct: 1123 YYNPPHECEWHYEPCGNRSFETCRTINGIHSNISVS---------YLEGCYPRCPKDRPI 1173

Query: 673  FSTSAQVCVPTGCPRCL-----GPHGEPVKVGHTVGMDCQECTCEAATWTLTCRPK 723
            +    + CV      C       P G  V    T    C+ C C  ++  + CRP+
Sbjct: 1174 YEEDLKKCVTADKCGCYVEDTHYPPGASVPTEET----CKSCVCTNSS-QVVCRPE 1224



 Score =  100 bits (248), Expect = 1e-20
 Identities = 100/375 (26%), Positives = 139/375 (37%), Gaps = 48/375 (12%)

Query: 394 VCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVLVDNYFCGAEDGLSCPRSI 453
           VCS WG+ HY TFDG  + F   C Y         Y  F V +     G  +  +   SI
Sbjct: 36  VCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRG-PGQAEAPAGVESI 94

Query: 454 ILEYHQDRVVLTRKPVHGVMTNEIIFNNKVVSPGF--RKNGI---VVSRIGVKMY----- 503
           +L    D + LTR   H  + N  + +    SPG    K+     V SR G+ +      
Sbjct: 95  LLTIKDDTIYLTR---HLAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLTLMWNRED 151

Query: 504 ATIPELGV--------------------QVMFSGLIFSVEVPFSKFANNTEGQCXXXXXX 543
           A + EL                      + +  G++FS  + F       +         
Sbjct: 152 ALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFS-PLEFGNMQKINQPDVVCEDPE 210

Query: 544 XTTPPAPCLPSPI-CQ-LILSKVFEPCHTVIPPLLFYEGCVFDRCHMTDLDV-VCSSLEL 600
               PA C      C+ L+ ++ F  C  ++P   +   C  DRC     D  VCS++  
Sbjct: 211 EEVAPASCSEHRAECERLLTAEAFADCQDLVPLEPYLRACQQDRCRCPGGDTCVCSTVAE 270

Query: 601 YAALCASHDICIDWRGRTGHMCPFTCPADKVYQPCGPSNPSYCYGNDSASLGALPEAGPI 660
           ++  C SH        RT  +CP TCP + VY   G      C   + +SL         
Sbjct: 271 FSRQC-SHAGGRPGNWRTATLCPKTCPGNLVYLESGSPCMDTCSHLEVSSLCEEHRM--- 326

Query: 661 TEGCFCPEGMTLFSTSAQVCVPTGCPRCLGPHGEPVKVGHTVGMDCQECTCEAATWTLTC 720
            +GCFCPEG          CVP     C   HG     G  +  DC++C C A  W    
Sbjct: 327 -DGCFCPEGTVYDDIGDSGCVPVSQCHC-RLHGHLYTPGQEITNDCEQCVCNAGRWVC-- 382

Query: 721 RPKLCPLPPACPLPG 735
             K  P P  C L G
Sbjct: 383 --KDLPCPGTCALEG 395



 Score = 93.6 bits (231), Expect = 9e-19
 Identities = 123/539 (22%), Positives = 197/539 (36%), Gaps = 81/539 (15%)

Query: 386 CHHYQCQCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVLVDNYFCGAED 445
           C    C   C+  G  H  TFDG  YTF  +C YVL +        + +L +   CG+ D
Sbjct: 382 CKDLPCPGTCALEGGSHITTFDGKTYTFHGDCYYVLAKG--DHNDSYALLGELAPCGSTD 439

Query: 446 GLSCPRSIILEYHQDRVVLTRKPVHGVMTNEIIFNNKVVSPGFR-----KNGIVVSR-IG 499
             +C ++++L   + + V+  K    V+ NE+  N   V+  F         I+VS  IG
Sbjct: 440 KQTCLKTVVLLADKKKNVVVFKSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVSMAIG 499

Query: 500 VKMYATIPEL----------------GVQVMFSGLIFS--------VEVPFSKFANNTEG 535
           V++   +  +                G+   F+GL           VE   + FAN  + 
Sbjct: 500 VRLQVQLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKA 559

Query: 536 Q--CXXXXXXXTTPPAPCLPSPI-----CQLI--LSKVFEPCHTVIPPLLFYEGCVFDRC 586
           Q  C         P +  + S       C L+      F  CH+ + P  +Y+ C +D C
Sbjct: 560 QSSCHDKLDWLDDPCSLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTC 619

Query: 587 H-MTDLDVVCSSLELYAALCASHDICI-DWRGRTGHMCPFTCPADKVYQPCGPSNPSYCY 644
           +   + D +C++L  YA  C +  + +  WR    +    +CP  +V+     +    C 
Sbjct: 620 NCQNNEDCLCAALSSYARACTAKGVMLWGWREHVCNKDVGSCPNSQVFLYNLTTCQQTCR 679

Query: 645 GNDSASLGALPEAGPITEGCFCPEGMTLFSTSAQVCVPTGCPRCLGPHGEPVKVGHTVGM 704
               A    L    P+ +GC CP+    F      CVP     C    G  ++ G  V  
Sbjct: 680 SLSEADSHCLEGFAPV-DGCGCPD--HTFLDEKGRCVPLAKCSCY-HRGLYLEAGDVVVR 735

Query: 705 DCQECTCEAATWTLTCRPKLCPLPPACPLP-------GFVPVPAAPQAGQCCPQYSCACN 757
             + C C      L CR ++  +  +C  P           +  +      C   +    
Sbjct: 736 QEERCVCRDG--RLHCR-QIRLIGQSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYY 792

Query: 758 TSRCPKPVGCPEGARAIPTYQEGACCPVQNCSWTVCSINGTLYQPGAVVSSSLCETCRCE 817
            + C     CP+G   +     G C   + C    C  N  LY  GA +    C TC C+
Sbjct: 793 HTECVSGCVCPDG---LMDDGRGGCVVEKECP---CVHNNDLYSSGAKIKVD-CNTCTCK 845

Query: 818 LPGGPPSDAFVVSCETQICNTHCPV---------GFEYQEQSGQCCGTCVQVACVTNTS 867
                    +V  C   +C+  C +           +Y +  G C    VQ  C  N+S
Sbjct: 846 ------RGRWV--CTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSS 896



 Score = 51.2 bits (121), Expect = 5e-06
 Identities = 27/57 (47%), Positives = 36/57 (63%), Gaps = 2/57 (3%)

Query: 47   PTTSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDCHP 103
            PTT+  + PT++TT  P TTPSP PTT+TTP   T+ S    + TT S P+T+   P
Sbjct: 1621 PTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPS--PPTTTTPSPPITTTTTP 1675



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 31/82 (37%), Positives = 39/82 (47%), Gaps = 6/82 (7%)

Query: 45   PVPTTSTTSAPTTSTTSGPGTTPSP------VPTTSTTPVSKTSTSHLSVSKTTHSQPVT 98
            P PTT+TT  PTT+ +    TTPSP       P  +TTP   T+T+      TT S P T
Sbjct: 1564 PPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTT 1623

Query: 99   SDCHPLCAWTKWFDVDFPSPGP 120
            +   P  + T       PSP P
Sbjct: 1624 TPITPPTSTTTLPPTTTPSPPP 1645



 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 30/79 (37%), Positives = 39/79 (49%), Gaps = 7/79 (8%)

Query: 47   PTTSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVS-------KTTHSQPVTS 99
            PTT+  + PT++TT  P TTPSP PTT+TTP   T+ S  + +        TT   P T+
Sbjct: 1542 PTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTT 1601

Query: 100  DCHPLCAWTKWFDVDFPSP 118
               P    T       PSP
Sbjct: 1602 PSPPTTTTTTPPPTTTPSP 1620



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 34/90 (37%), Positives = 42/90 (46%), Gaps = 14/90 (15%)

Query: 45   PVPTTSTTSAPTTSTTS-GPGTTPSPVPTT-------------STTPVSKTSTSHLSVSK 90
            P P T+T S PTT+TT+  P TTPSP  TT             +TTP   T+T+      
Sbjct: 1477 PSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPT 1536

Query: 91   TTHSQPVTSDCHPLCAWTKWFDVDFPSPGP 120
            TT S P T+   P  + T       PSP P
Sbjct: 1537 TTPSPPTTTPITPPTSTTTLPPTTTPSPPP 1566



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 30/83 (36%), Positives = 38/83 (45%), Gaps = 7/83 (8%)

Query: 45   PVPTTSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSK-------TSTSHLSVSKTTHSQPV 97
            P PTT+TT  PTT+ +    TTPSP  TT+TTP          T+T     +  T   P 
Sbjct: 1643 PPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPT 1702

Query: 98   TSDCHPLCAWTKWFDVDFPSPGP 120
            T+   P+   T       PSP P
Sbjct: 1703 TTPSSPITTTTTPSSTTTPSPPP 1725



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 25/57 (43%), Positives = 33/57 (57%), Gaps = 2/57 (3%)

Query: 47   PTTSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDCHP 103
            PTT+ +  PTT+TT  P TTPSP   T+TTP    +T+      TT S P+T+   P
Sbjct: 1637 PTTTPSPPPTTTTTPPPTTTPSP--PTTTTPSPPITTTTTPPPTTTPSSPITTTPSP 1691



 Score = 43.9 bits (102), Expect = 8e-04
 Identities = 26/74 (35%), Positives = 33/74 (44%)

Query: 45   PVPTTSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDCHPL 104
            P P T TT+ P  +TT  P TT +  P  +TTP   T+T     + TT   P T+   P 
Sbjct: 1586 PSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPP 1645

Query: 105  CAWTKWFDVDFPSP 118
               T       PSP
Sbjct: 1646 TTTTTPPPTTTPSP 1659



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 23/59 (38%), Positives = 30/59 (50%)

Query: 45   PVPTTSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDCHP 103
            P P T+TT+ P  +TT  P TT    P TSTT +  T+T     + TT   P T+   P
Sbjct: 1523 PSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPP 1581



 Score = 40.0 bits (92), Expect = 0.012
 Identities = 75/333 (22%), Positives = 120/333 (36%), Gaps = 55/333 (16%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 3981 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 4038

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAESHPEVNIE 161
             P+   T       P+P P G    T   I  +           T      ++     I 
Sbjct: 4039 -PITTTT----TVTPTPTPTGTQTPTTTPITTT------TTVTPTPTPTGTQTPTTTPIT 4087

Query: 162  HLGQVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCPVTSVTPYGT------ 215
                V       G        Q P    +     V    TP G    + TP  T      
Sbjct: 4088 TTTTVTPTPTPTG-------TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 4140

Query: 216  --SPTNALYPSLSTSMVSASVASTSVASSSVASSSVAYSTQTCFCNVADRLYPAGSTIYR 273
              +PT    P+ +    + +V  T   + +   ++   +T T    V     P G+    
Sbjct: 4141 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT---TVTPTPTPTGTQ--- 4194

Query: 274  HRDLAGHCYYALCSQDCQVVRGVDSDCPSTTLPPAPATSP--SISTSEPVTE-LGCPNAV 330
                 G   +   +   ++         +T+ PP  +++P  S STS P+TE     + +
Sbjct: 4195 ----TGPPTHTSTAPIAEL---------TTSNPPPESSTPQTSRSTSSPLTESTTLLSTL 4241

Query: 331  PPRKKGETWATPNCSEA--TCEGNNVISLRPRT 361
            PP  +  + A P+   A  T  G + +S  P T
Sbjct: 4242 PPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPST 4274



 Score = 39.7 bits (91), Expect = 0.015
 Identities = 28/65 (43%), Positives = 34/65 (52%), Gaps = 8/65 (12%)

Query: 45   PVPTTS----TTSAP--TTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVT 98
            P  TT+    TT +P  TT+TT  P TTPSP  TT  TP   TST+ L  + T    P T
Sbjct: 1511 PASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITP--PTSTTTLPPTTTPSPPPTT 1568

Query: 99   SDCHP 103
            +   P
Sbjct: 1569 TTTPP 1573



 Score = 39.7 bits (91), Expect = 0.015
 Identities = 27/81 (33%), Positives = 39/81 (48%), Gaps = 7/81 (8%)

Query: 47   PTTSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDCHPLCA 106
            PT  TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+   P+  
Sbjct: 1893 PTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITT 1949

Query: 107  WTKWFDVDFPSPGPHGGDKET 127
             T       P+P P G    T
Sbjct: 1950 TT----TVTPTPTPTGTQTPT 1966



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 26/72 (36%), Positives = 33/72 (45%), Gaps = 1/72 (1%)

Query: 47   PTTSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDCHPLCA 106
            P  STT+ P T+T S P TT +  P  +TTP   T+T     + TT   P T+   P   
Sbjct: 1510 PPASTTTLPPTTTPS-PPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTT 1568

Query: 107  WTKWFDVDFPSP 118
             T       PSP
Sbjct: 1569 TTTPPPTTTPSP 1580



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 1911 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 1968

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 1969 -PITTTT----TVTPTPTPTGTQTPT 1989



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 1934 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 1991

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 1992 -PITTTT----TVTPTPTPTGTQTPT 2012



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 1957 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 2014

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 2015 -PITTTT----TVTPTPTPTGTQTPT 2035



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 1980 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 2037

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 2038 -PITTTT----TVTPTPTPTGTQTPT 2058



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 2003 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 2060

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 2061 -PITTTT----TVTPTPTPTGTQTPT 2081



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 2026 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 2083

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 2084 -PITTTT----TVTPTPTPTGTQTPT 2104



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 2049 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 2106

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 2107 -PITTTT----TVTPTPTPTGTQTPT 2127



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 2072 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 2129

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 2130 -PITTTT----TVTPTPTPTGTQTPT 2150



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 2095 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 2152

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 2153 -PITTTT----TVTPTPTPTGTQTPT 2173



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 2118 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 2175

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 2176 -PITTTT----TVTPTPTPTGTQTPT 2196



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 2141 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 2198

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 2199 -PITTTT----TVTPTPTPTGTQTPT 2219



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 2164 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 2221

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 2222 -PITTTT----TVTPTPTPTGTQTPT 2242



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 2187 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 2244

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 2245 -PITTTT----TVTPTPTPTGTQTPT 2265



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 2210 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 2267

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 2268 -PITTTT----TVTPTPTPTGTQTPT 2288



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 2233 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 2290

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 2291 -PITTTT----TVTPTPTPTGTQTPT 2311



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 2256 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 2313

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 2314 -PITTTT----TVTPTPTPTGTQTPT 2334



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 2279 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 2336

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 2337 -PITTTT----TVTPTPTPTGTQTPT 2357



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 2302 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 2359

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 2360 -PITTTT----TVTPTPTPTGTQTPT 2380



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 2325 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 2382

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 2383 -PITTTT----TVTPTPTPTGTQTPT 2403



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 2348 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 2405

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 2406 -PITTTT----TVTPTPTPTGTQTPT 2426



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 2371 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 2428

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 2429 -PITTTT----TVTPTPTPTGTQTPT 2449



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 2394 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 2451

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 2452 -PITTTT----TVTPTPTPTGTQTPT 2472



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 2417 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 2474

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 2475 -PITTTT----TVTPTPTPTGTQTPT 2495



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 2440 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 2497

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 2498 -PITTTT----TVTPTPTPTGTQTPT 2518



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 2463 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 2520

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 2521 -PITTTT----TVTPTPTPTGTQTPT 2541



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 2486 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 2543

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 2544 -PITTTT----TVTPTPTPTGTQTPT 2564



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 2509 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 2566

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 2567 -PITTTT----TVTPTPTPTGTQTPT 2587



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 2532 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 2589

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 2590 -PITTTT----TVTPTPTPTGTQTPT 2610



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 2555 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 2612

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 2613 -PITTTT----TVTPTPTPTGTQTPT 2633



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 2578 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 2635

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 2636 -PITTTT----TVTPTPTPTGTQTPT 2656



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 2601 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 2658

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 2659 -PITTTT----TVTPTPTPTGTQTPT 2679



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 2624 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 2681

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 2682 -PITTTT----TVTPTPTPTGTQTPT 2702



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 2647 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 2704

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 2705 -PITTTT----TVTPTPTPTGTQTPT 2725



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 2670 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 2727

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 2728 -PITTTT----TVTPTPTPTGTQTPT 2748



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 2693 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 2750

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 2751 -PITTTT----TVTPTPTPTGTQTPT 2771



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 2716 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 2773

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 2774 -PITTTT----TVTPTPTPTGTQTPT 2794



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 2739 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 2796

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 2797 -PITTTT----TVTPTPTPTGTQTPT 2817



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 2762 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 2819

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 2820 -PITTTT----TVTPTPTPTGTQTPT 2840



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 2785 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 2842

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 2843 -PITTTT----TVTPTPTPTGTQTPT 2863



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 2808 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 2865

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 2866 -PITTTT----TVTPTPTPTGTQTPT 2886



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 2831 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 2888

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 2889 -PITTTT----TVTPTPTPTGTQTPT 2909



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 2854 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 2911

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 2912 -PITTTT----TVTPTPTPTGTQTPT 2932



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 2877 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 2934

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 2935 -PITTTT----TVTPTPTPTGTQTPT 2955



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 2900 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 2957

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 2958 -PITTTT----TVTPTPTPTGTQTPT 2978



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 2923 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 2980

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 2981 -PITTTT----TVTPTPTPTGTQTPT 3001



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 2946 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 3003

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 3004 -PITTTT----TVTPTPTPTGTQTPT 3024



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 2969 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 3026

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 3027 -PITTTT----TVTPTPTPTGTQTPT 3047



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 2992 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 3049

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 3050 -PITTTT----TVTPTPTPTGTQTPT 3070



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 3015 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 3072

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 3073 -PITTTT----TVTPTPTPTGTQTPT 3093



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 3038 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 3095

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 3096 -PITTTT----TVTPTPTPTGTQTPT 3116



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 3061 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 3118

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 3119 -PITTTT----TVTPTPTPTGTQTPT 3139



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 3084 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 3141

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 3142 -PITTTT----TVTPTPTPTGTQTPT 3162



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 3107 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 3164

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 3165 -PITTTT----TVTPTPTPTGTQTPT 3185



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 3130 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 3187

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 3188 -PITTTT----TVTPTPTPTGTQTPT 3208



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 3153 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 3210

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 3211 -PITTTT----TVTPTPTPTGTQTPT 3231



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 3176 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 3233

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 3234 -PITTTT----TVTPTPTPTGTQTPT 3254



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 3199 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 3256

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 3257 -PITTTT----TVTPTPTPTGTQTPT 3277



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 3222 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 3279

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 3280 -PITTTT----TVTPTPTPTGTQTPT 3300



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 3245 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 3302

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 3303 -PITTTT----TVTPTPTPTGTQTPT 3323



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 3268 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 3325

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 3326 -PITTTT----TVTPTPTPTGTQTPT 3346



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 3291 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 3348

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 3349 -PITTTT----TVTPTPTPTGTQTPT 3369



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 3314 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 3371

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 3372 -PITTTT----TVTPTPTPTGTQTPT 3392



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 3337 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 3394

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 3395 -PITTTT----TVTPTPTPTGTQTPT 3415



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 3360 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 3417

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 3418 -PITTTT----TVTPTPTPTGTQTPT 3438



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 3383 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 3440

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 3441 -PITTTT----TVTPTPTPTGTQTPT 3461



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 3406 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 3463

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 3464 -PITTTT----TVTPTPTPTGTQTPT 3484



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 3429 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 3486

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 3487 -PITTTT----TVTPTPTPTGTQTPT 3507



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 3452 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 3509

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 3510 -PITTTT----TVTPTPTPTGTQTPT 3530



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 3475 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 3532

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 3533 -PITTTT----TVTPTPTPTGTQTPT 3553



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 3498 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 3555

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 3556 -PITTTT----TVTPTPTPTGTQTPT 3576



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 3521 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 3578

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 3579 -PITTTT----TVTPTPTPTGTQTPT 3599



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 3544 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 3601

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 3602 -PITTTT----TVTPTPTPTGTQTPT 3622



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 3567 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 3624

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 3625 -PITTTT----TVTPTPTPTGTQTPT 3645



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 3590 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 3647

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 3648 -PITTTT----TVTPTPTPTGTQTPT 3668



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 3613 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 3670

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 3671 -PITTTT----TVTPTPTPTGTQTPT 3691



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 3636 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 3693

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 3694 -PITTTT----TVTPTPTPTGTQTPT 3714



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 3659 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 3716

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 3717 -PITTTT----TVTPTPTPTGTQTPT 3737



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 3682 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 3739

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 3740 -PITTTT----TVTPTPTPTGTQTPT 3760



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 3705 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 3762

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 3763 -PITTTT----TVTPTPTPTGTQTPT 3783



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 3728 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 3785

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 3786 -PITTTT----TVTPTPTPTGTQTPT 3806



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 3751 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 3808

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 3809 -PITTTT----TVTPTPTPTGTQTPT 3829



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 3774 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 3831

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 3832 -PITTTT----TVTPTPTPTGTQTPT 3852



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 3797 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 3854

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 3855 -PITTTT----TVTPTPTPTGTQTPT 3875



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 3820 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 3877

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 3878 -PITTTT----TVTPTPTPTGTQTPT 3898



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 3843 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 3900

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 3901 -PITTTT----TVTPTPTPTGTQTPT 3921



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 3866 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 3923

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 3924 -PITTTT----TVTPTPTPTGTQTPT 3944



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 3889 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 3946

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 3947 -PITTTT----TVTPTPTPTGTQTPT 3967



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 3912 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 3969

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 3970 -PITTTT----TVTPTPTPTGTQTPT 3990



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 3935 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 3992

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 3993 -PITTTT----TVTPTPTPTGTQTPT 4013



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+  
Sbjct: 3958 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-- 4015

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 4016 -PITTTT----TVTPTPTPTGTQTPT 4036



 Score = 38.5 bits (88), Expect = 0.034
 Identities = 27/71 (38%), Positives = 38/71 (53%), Gaps = 6/71 (8%)

Query: 41   HNLCPVPTTSTT--SAPTTSTTSGPGT--TPSPVPTTSTTPVSKTST--SHLSVSKTTHS 94
            H L P P+T+T+    PT  TT+G  +  TPS V TT+T+  + T T  S  S+ +TT  
Sbjct: 4266 HTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGL 4325

Query: 95   QPVTSDCHPLC 105
            +P  S     C
Sbjct: 4326 RPYPSSVLICC 4336



 Score = 32.0 bits (71), Expect = 3.2
 Identities = 24/66 (36%), Positives = 36/66 (54%), Gaps = 7/66 (10%)

Query: 36   CLYSQHNL--CPVPTTSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTH 93
            CL  + N+  C   T  TT   TT+TT  P T P+  P T+TT V+ T T   + ++T  
Sbjct: 1866 CLNYEINVQCCECVTQPTTM--TTTTTENP-TPPTTTPITTTTTVTPTPTP--TGTQTPT 1920

Query: 94   SQPVTS 99
            + P+T+
Sbjct: 1921 TTPITT 1926


>gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]
          Length = 2639

 Score =  536 bits (1381), Expect = e-152
 Identities = 340/1075 (31%), Positives = 473/1075 (44%), Gaps = 96/1075 (8%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT   TT+TT  P  TP+   +T+ TP++ T+T   + + T    P     
Sbjct: 1579 PTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMI-- 1636

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAESHPEVNIE 161
             P+   T       P+ G  G    T    I         PE  T    R+ S P     
Sbjct: 1637 -PISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTEST 1695

Query: 162  HLGQVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCET--PRGCPVTSVTPYGTS-PT 218
             L   +  + E            P      + +      T  P G P    T   +S PT
Sbjct: 1696 TLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPT 1755

Query: 219  NALYPSLSTSMVSASVASTSVASSSVASSSVAYSTQTCFCNVA-DRLYPAGSTIYRHRDL 277
             +   + +TS  + +    S  S    +    Y +    C V  D  Y  G  +Y +   
Sbjct: 1756 PSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVY-NGTY 1814

Query: 278  AGHCYYALCSQDCQVVRGVDSDCPSTTLP-PAPATS------PSISTSEPVTELG---CP 327
               CY+  CS  C  +   +  CPST  P P P+ S      PS + S+P        CP
Sbjct: 1815 GDTCYFVNCSLSC-TLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECP 1873

Query: 328  NAVPPRKKGETWATPNCSEATCEGNNVISLRPRTCPRVEKPTCANGYPAVKVADQDGCCH 387
            +  PPR++ ETW   +C  ATC+ NN + +    C     PTC+NG   V+V D DGCC 
Sbjct: 1874 DFDPPRQENETWWLCDCFMATCKYNNTVEIVKVECEPPPMPTCSNGLQPVRVEDPDGCCW 1933

Query: 388  HYQCQCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVLVDNYFCGAEDGL 447
            H++C C C+GWGDPHY+TFDG YY++  NCTYVLV++I P   +F V +DNY C   D +
Sbjct: 1934 HWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKV 1993

Query: 448  SCPRSIILEYHQDRVVLTRKPVHGV-MTNEIIFNNKVVSPGFRKNGIVVSRIGVKMYATI 506
            SCPR++I+ +    V++  K VH + M  ++  N + V+  ++K G+ V + G+     I
Sbjct: 1994 SCPRTLIVRHETQEVLI--KTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDI 2051

Query: 507  PELGVQVMFSGLIFSVEVPFSKFA-----------NNTEGQCXXXXXXX----------- 544
            PELGV V ++GL FSV +P+ +F            N T   C                  
Sbjct: 2052 PELGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQW 2111

Query: 545  -----------------------------TTPPAPCLPSPICQLILSKVFEPCHTVIPPL 575
                                         TTP   C PSP+CQLI   +F  CH ++PP 
Sbjct: 2112 LVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQ 2171

Query: 576  LFYEGCVFDRCHMTDLDVVCSSLELYAALCASHDICIDWRGRTGHMCPFTCPADKVYQPC 635
             +Y+ CVFD C M    + C+SL+ YAALCA  +IC+DWR  T   C   CP+ + YQ C
Sbjct: 2172 HYYDACVFDSCFMPGSSLECASLQAYAALCAQQNICLDWRNHTHGACLVECPSHREYQAC 2231

Query: 636  GPSNPSYCYGNDSASLGALPEAGPITEGCFCPEGMTLFSTSAQVCVPTGCPRCLGPHGEP 695
            GP+    C  + S     +     + EGCFCPEG   ++    VCV T C  C+GP   P
Sbjct: 2232 GPAEEPTCKSSSSQQNNTV-----LVEGCFCPEGTMNYAPGFDVCVKT-C-GCVGPDNVP 2284

Query: 696  VKVGHTVGMDCQECTCEAATWTLTCRPKLCPLPPA--CPLPGFVPVPAAPQAGQCCPQYS 753
             + G     DC+ C C      + C+PK C   P   C   G         A  CC    
Sbjct: 2285 REFGEHFEFDCKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTCCNITV 2344

Query: 754  CACNTSRC-PKPVGCPEGARAIPTYQEGACCPVQNC-SWTVCSINGTLYQPGAVVSSSLC 811
            C CNTS C  KP  CP G         G CCP   C S  VC      YQPG+ V SS C
Sbjct: 2345 CKCNTSLCKEKPSVCPLGFEVKSKMVPGRCCPFYWCESKGVCVHGNAEYQPGSPVYSSKC 2404

Query: 812  ETCRCELPGGPPSDAFVVSCETQICNTHCPVGFEYQEQSGQCCGTCVQVACVTNTSKSPA 871
            + C C       +   V++C    CNT C  GFE  E  G+CC  C Q  C+     +  
Sbjct: 2405 QDCVCTDKVDNNTLLNVIACTHVPCNTSCSPGFELMEAPGECCKKCEQTHCIIKRPDNQH 2464

Query: 872  HLFYPGETWSDAGNHCVTHQCEKHQDGLVVVTTKKACPPLSCSL---DEARMSKDGCCRF 928
             +  PG+  SD  N+C    C K  + L+   +   CP    S+          +GCC+ 
Sbjct: 2465 VILKPGDFKSDPKNNCTFFSCVKIHNQLISSVSNITCPNFDASICIPGSITFMPNGCCKT 2524

Query: 929  CPPPPPPYQNQSTCAVYHRSLIIQQQGCSSSEPVRLAYCRGNCGDSSSMYSLEGNTVEHR 988
            C    P  + +  C+    +  +   GC+ +  V + +C G+CG +  MYS +   ++H 
Sbjct: 2525 C---TPRNETRVPCSTVPVTTEVSYAGCTKT--VLMNHCSGSCG-TFVMYSAKAQALDHS 2578

Query: 989  CQCCQELRTSLRNVTLHCTDGSSRAFSYTEVEECGCMGRRCPAPGDTQHSEEAEP 1043
            C CC+E +TS R V L C +G S   +YT +E C C    C  P  T       P
Sbjct: 2579 CSCCKEEKTSQREVVLSCPNGGSLTHTYTHIESCQCQDTVCGLPTGTSRRARRSP 2633



 Score =  110 bits (276), Expect = 5e-24
 Identities = 126/536 (23%), Positives = 194/536 (36%), Gaps = 97/536 (18%)

Query: 256  CFCNVADRLYPAGSTIYRHRDLAGHCYYALCSQDCQVVRGVDSDCPSTTLPPAPATSPSI 315
            C C        AG  + R  +    C        C+ +R +   C +  +    +   ++
Sbjct: 619  CSCYHRGLYLEAGDVVVRQEE---RCVCRDGRLHCRQIRLIGQSCTAPKIHMDCSNLTAL 675

Query: 316  STSEPVTELGCPNAVPPRKKGETWATPNCSEATCEGNNVISLRPRTCPRVEKPTCANGYP 375
            +TS+P   L C          E  +   C +   +      +  + CP V      +   
Sbjct: 676  ATSKP-RALSCQTLAAGYYHTECVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGA 734

Query: 376  AVKVADQDGC--------CHHYQCQCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIV- 426
             +KV D + C        C    C   CS +G  HYITFDG YY F  +C+YV VQ    
Sbjct: 735  KIKV-DCNTCTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCG 793

Query: 427  --PVYGHFRVLVDNYFCGAEDGLSCPRSIILEY--------HQDRVVLTRKPVHGVM-TN 475
                 G F ++ +N  CG   G++C ++I +           + RVV+ R   H V  T 
Sbjct: 794  QNSSLGSFSIITENVPCGTT-GVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYTT 852

Query: 476  EIIFNNKVVSPGFRKNGIVVSRIGVKMYATIPELGVQVMFSGLIFSVEVPFSKFANN--- 532
              +    VV       GI+V    +    T   + +   + G +  +   F   +NN   
Sbjct: 853  REVGQYLVVESS---TGIIV----IWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFT 905

Query: 533  --------------TEGQCXXXXXXXTTPPAPCLPSPI--------CQLILSKVFEPCHT 570
                             +        +T P PC  +P         C ++ S VF  CH+
Sbjct: 906  TRDHMVVSSELDFGNSWKEAPTCPDVSTNPEPCSLNPHRRSWAEKQCSILKSSVFSICHS 965

Query: 571  VIPPLLFYEGCVFDRCHMT---DLDVVCSSLELYAALCASHDICIDWRGRTGHMCPFTC- 626
             + P  FYE CV D C      D +  CS++  YA  C     C+ W  RT  +CP  C 
Sbjct: 966  KVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACVFW--RTPDLCPIFCD 1023

Query: 627  ------PADKVYQPCGPSNPSYC------YGNDSASLGALPEAGPITEGCF--CPEGMTL 672
                    +  Y+PCG  +   C      + N S S           EGC+  CP+   +
Sbjct: 1024 YYNPPHECEWHYEPCGNRSFETCRTINGIHSNISVS---------YLEGCYPRCPKDRPI 1074

Query: 673  FSTSAQVCVPTGCPRCL-----GPHGEPVKVGHTVGMDCQECTCEAATWTLTCRPK 723
            +    + CV      C       P G  V    T    C+ C C  ++  + CRP+
Sbjct: 1075 YEEDLKKCVTADKCGCYVEDTHYPPGASVPTEET----CKSCVCTNSS-QVVCRPE 1125



 Score =  104 bits (259), Expect = 5e-22
 Identities = 69/218 (31%), Positives = 103/218 (47%), Gaps = 35/218 (16%)

Query: 42   NLCPVPTTSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            N+C + T  +T   TT TT    TTP+   TT+TT    +ST   +  K           
Sbjct: 1155 NICSITTRPSTL--TTFTTITLPTTPTTFTTTTTTTTPTSSTVLSTTPKLC--------- 1203

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAESHPEVNIE 161
               C W+ W + D PS G   GD+ET++        +C  PE+I   +CR+   P +++E
Sbjct: 1204 ---CLWSDWINEDHPSSGSDDGDRETFDG-------VCGAPEDI---ECRSVKDPHLSLE 1250

Query: 162  HLGQVVQ--CSREEGLVCRNQDQQG----PFKMCLNYEVRVLCCETPRGCPVTSVTPYGT 215
             LGQ VQ  C    GL+C+N+DQ+     P   CLNYE+ V CCE      VT  T   T
Sbjct: 1251 QLGQKVQLVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCEC-----VTQPTTMTT 1305

Query: 216  SPTNALYPSLSTSMVSASVASTSVASSSVASSSVAYST 253
            + T    P+  T+  + +   T  ++ S   + +  +T
Sbjct: 1306 TTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTT 1343



 Score = 70.9 bits (172), Expect = 6e-12
 Identities = 109/511 (21%), Positives = 182/511 (35%), Gaps = 84/511 (16%)

Query: 414 LDNCTYVLVQQIVPVYGHFRVLVDNYFCGAEDGLSCPRSIILEYHQDRVVLTRKPVHGVM 473
           +D C+++ V  +   +      +D  FC        P++++L   + + V+  K    V+
Sbjct: 314 MDTCSHLEVSSLCEEHR-----MDGCFCPEGAQADLPKTVVLLADKKKNVVVFKSDGSVL 368

Query: 474 TNEIIFNNKVVSPGFR-----KNGIVVSR-IGVKMYATIPEL----------------GV 511
            NE+  N   V+  F         I+VS  IGV++   +  +                G+
Sbjct: 369 LNELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGL 428

Query: 512 QVMFSGLIFS--------VEVPFSKFANNTEGQ--CXXXXXXXTTPPAPCLPSPI----- 556
              F+GL           VE   + FAN  + Q  C         P +  + S       
Sbjct: 429 CGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKLDWLDDPCSLNIESANYAEHW 488

Query: 557 CQLI--LSKVFEPCHTVIPPLLFYEGCVFDRCH-MTDLDVVCSSLELYAALCASHDICI- 612
           C L+      F  CH+ + P  +Y+ C +D C+   + D +C++L  YA  C +  + + 
Sbjct: 489 CSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGVMLW 548

Query: 613 DWRGRTGHMCPFTCPADKVYQPCGPSNPSYCYGNDSASLGALPEAGPITEGCFCPEGMTL 672
            WR    +    +CP  +V+     +    C     A    L    P+ +GC CP+    
Sbjct: 549 GWREHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPV-DGCGCPD--HT 605

Query: 673 FSTSAQVCVPTGCPRCLGPHGEPVKVGHTVGMDCQECTCEAATWTLTCRPKLCPLPPACP 732
           F      CVP     C    G  ++ G  V    + C C      L CR ++  +  +C 
Sbjct: 606 FLDEKGRCVPLAKCSCY-HRGLYLEAGDVVVRQEERCVCRDG--RLHCR-QIRLIGQSCT 661

Query: 733 LP-------GFVPVPAAPQAGQCCPQYSCACNTSRCPKPVGCPEGARAIPTYQEGACCPV 785
            P           +  +      C   +     + C     CP+G   +     G C   
Sbjct: 662 APKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDG---LMDDGRGGCVVE 718

Query: 786 QNCSWTVCSINGTLYQPGAVVSSSLCETCRCELPGGPPSDAFVVSCETQICNTHCPV--- 842
           + C    C  N  LY  GA +    C TC C+         +V  C   +C+  C +   
Sbjct: 719 KECP---CVHNNDLYSSGAKIKVD-CNTCTCK------RGRWV--CTQAVCHGTCSIYGS 766

Query: 843 ------GFEYQEQSGQCCGTCVQVACVTNTS 867
                   +Y +  G C    VQ  C  N+S
Sbjct: 767 GHYITFDGKYYDFDGHCSYVAVQDYCGQNSS 797



 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 78/313 (24%), Positives = 118/313 (37%), Gaps = 46/313 (14%)

Query: 394 VCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVLVDNYFCGAEDGLSCPRSI 453
           VCS WG+ HY TFDG  + F   C Y         Y  F V +     G  +  +   SI
Sbjct: 36  VCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKR-GPGQAEAPAGVESI 94

Query: 454 ILEYHQDRVVLTRKPVHGVMTNEIIFNNKVVSPG--FRKNGI---VVSRIGVKMY----- 503
           +L    D + LTR   H  + N  + +    SPG    K+     V SR G+ +      
Sbjct: 95  LLTIKDDTIYLTR---HLAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLTLMWNRED 151

Query: 504 ATIPELGV--------------------QVMFSGLIFSVEVPFSKFANNTEGQCXXXXXX 543
           A + EL                      + +  G++FS  + F       +         
Sbjct: 152 ALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFS-PLEFGNMQKINQPDVVCEDPE 210

Query: 544 XTTPPAPCLP--SPICQLILSKVFEPCHTVIPPLLFYEGCVFDRCHMTDLDV-VCSSLEL 600
               PA C    +   +L+ ++ F  C  ++P   +   C  DRC     D  VCS++  
Sbjct: 211 EEVAPASCSEHRAECERLLTAEAFADCQDLVPLEPYLRACQQDRCRCPGGDTCVCSTVAE 270

Query: 601 YAALCA-SHDICIDWRGRTGHMCP---FTCPADKVYQPCGPSNPSYCYGNDSASLGALPE 656
           ++  C+ +     +WR  T  + P    TCP + VY   G      C   + +SL     
Sbjct: 271 FSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTCSHLEVSSLCEEHR 330

Query: 657 AGPITEGCFCPEG 669
                +GCFCPEG
Sbjct: 331 ----MDGCFCPEG 339



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 24/73 (32%), Positives = 37/73 (50%), Gaps = 5/73 (6%)

Query: 28   CSYNQNNLCLYSQHNLCPVP-TTSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHL 86
            C      +   +  N  P P TT+TT  PT + TS   TTP+P+ TT+T   + T T   
Sbjct: 1296 CVTQPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTG-- 1353

Query: 87   SVSKTTHSQPVTS 99
              ++T  + P+T+
Sbjct: 1354 --TQTPTTTPITT 1364



 Score = 40.0 bits (92), Expect = 0.012
 Identities = 29/84 (34%), Positives = 40/84 (47%), Gaps = 8/84 (9%)

Query: 45   PVPTTSTTSAP-TTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDCHP 103
            P  T STT  P TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+   P
Sbjct: 1328 PTSTQSTTPTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---P 1384

Query: 104  LCAWTKWFDVDFPSPGPHGGDKET 127
            +   T       P+P P G    T
Sbjct: 1385 ITTTT----TVTPTPTPTGTQTPT 1404



 Score = 38.5 bits (88), Expect = 0.034
 Identities = 87/402 (21%), Positives = 137/402 (34%), Gaps = 45/402 (11%)

Query: 45   PVPTTSTTSAPT-TSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDCHP 103
            P PT + T APT T+ T+    TP+P PT + TP +   T+  +V+ T    P  +    
Sbjct: 1439 PTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTGTQTPT 1496

Query: 104  LCAWTKWFDVDFPSPGPHGGDKETYNNIIR----------SGEKICRRPEEITRLQCRAE 153
              A T    V  P+P P G    T   I            +G +        T       
Sbjct: 1497 PTAITTTTTVT-PTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPT 1555

Query: 154  SHPEVNIEHLGQVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCPVTSVTPY 213
              P          +  +            Q P  + +     +    TP     T+VTP 
Sbjct: 1556 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPI 1615

Query: 214  GTSPTNALYP----SLSTSMVSASVASTSVASSSVASSSVAYSTQTCFCNVADRLY---- 265
             T+ T    P    + + +M+  S  +T   + +  + S    T T    +A+       
Sbjct: 1616 TTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPP 1675

Query: 266  PAGSTIYRHRDLAGHCYYA--LCSQDCQVVRGVDSDCPSTTLPPAPATSPSIST-SEPVT 322
            P  ST    R  +     +  L S     +    +  PST  P AP T+    T S P +
Sbjct: 1676 PESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPST--PTAPTTTSGGHTLSPPPS 1733

Query: 323  ELGCPNAVPPR--KKGETWA-TPNCSEATCEGNNVISLRPRTCPRVEKPTCANGYPAVKV 379
                P   P R    G + A TP+  + T       +  P + P + + T    YP+  +
Sbjct: 1734 TTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVL 1793

Query: 380  ADQDGCCHHYQCQCVCSGWGDPHYITFDGTYY-TFLDNCTYV 420
                          +C    D +Y   +  Y  T+ D C +V
Sbjct: 1794 --------------ICCVLNDTYYAPGEEVYNGTYGDTCYFV 1821



 Score = 38.5 bits (88), Expect = 0.034
 Identities = 27/71 (38%), Positives = 38/71 (53%), Gaps = 6/71 (8%)

Query: 41   HNLCPVPTTSTT--SAPTTSTTSGPGT--TPSPVPTTSTTPVSKTST--SHLSVSKTTHS 94
            H L P P+T+T+    PT  TT+G  +  TPS V TT+T+  + T T  S  S+ +TT  
Sbjct: 1726 HTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGL 1785

Query: 95   QPVTSDCHPLC 105
            +P  S     C
Sbjct: 1786 RPYPSSVLICC 1796



 Score = 37.7 bits (86), Expect = 0.058
 Identities = 28/86 (32%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P ++  
Sbjct: 1349 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTST-- 1406

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 1407 -PITTTT----TVTPTPTPTGTQTPT 1427



 Score = 37.7 bits (86), Expect = 0.058
 Identities = 28/86 (32%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            P PT   T TT+  TT+TT  P  TP+   T ++TP++ T+T   + + T    P T+  
Sbjct: 1372 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTTT-- 1429

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127
             P+   T       P+P P G    T
Sbjct: 1430 -PITTTT----TVTPTPTPTGTQAPT 1450



 Score = 36.2 bits (82), Expect = 0.17
 Identities = 29/87 (33%), Positives = 43/87 (49%), Gaps = 10/87 (11%)

Query: 45   PVPTTSTTSAPTT---STTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKT-THSQPVTSD 100
            P PT + T  PTT   +TT+    TP+P  T + TP + T+TS ++ + T T +Q  T+ 
Sbjct: 1416 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTTT 1475

Query: 101  CHPLCAWTKWFDVDFPSPGPHGGDKET 127
              P+   T       P+P P G    T
Sbjct: 1476 --PITTTT----TVTPTPTPTGTQTPT 1496



 Score = 35.8 bits (81), Expect = 0.22
 Identities = 21/61 (34%), Positives = 34/61 (55%), Gaps = 3/61 (4%)

Query: 39   SQHNLCPVPTTSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVT 98
            S  +  P P T+TT+   T T +G   TP+  P T+TT V+ T T   + ++T  + P+T
Sbjct: 1330 STQSTTPTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTP--TGTQTPTTTPIT 1386

Query: 99   S 99
            +
Sbjct: 1387 T 1387



 Score = 34.7 bits (78), Expect = 0.49
 Identities = 26/68 (38%), Positives = 35/68 (51%), Gaps = 11/68 (16%)

Query: 36   CLYSQHNL--CPVPTTSTTSAPTTSTTSGPGTTPSPVPTTST-----TPVSKTSTSHLSV 88
            CL  + N+  C   T  TT   TT+TT  P  TP+P+ TT+T     TP S  ST+   +
Sbjct: 1284 CLNYEINVQCCECVTQPTTM--TTTTTENP--TPTPITTTTTVTPTPTPTSTQSTTPTPI 1339

Query: 89   SKTTHSQP 96
            + TT   P
Sbjct: 1340 TTTTTVTP 1347



 Score = 34.7 bits (78), Expect = 0.49
 Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 12/85 (14%)

Query: 48   TTSTTSAPT-TSTTSGPGTTPSPVPT----TSTTPVSKTSTSHLSVSKTTHSQPVTSDCH 102
            TT+TT  PT T  T+    TP+P PT    T+ TP++ T+T   + + T    P T+   
Sbjct: 1304 TTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQTPTTT--- 1360

Query: 103  PLCAWTKWFDVDFPSPGPHGGDKET 127
            P+   T       P+P P G    T
Sbjct: 1361 PITTTT----TVTPTPTPTGTQTPT 1381



 Score = 32.3 bits (72), Expect = 2.4
 Identities = 21/60 (35%), Positives = 29/60 (48%), Gaps = 1/60 (1%)

Query: 45   PVPTTSTTSAPTTSTTSGPGT-TPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDCHP 103
            P  T  TT+   T T +  GT TP+  P T+TT V+ T T   + + T  +   TS   P
Sbjct: 1403 PTSTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTP 1462


>gi|169202626 PREDICTED: similar to mucin 5, partial [Homo sapiens]
          Length = 2013

 Score =  277 bits (709), Expect = 3e-74
 Identities = 141/217 (64%), Positives = 160/217 (73%), Gaps = 7/217 (3%)

Query: 46   VPTTSTTSAPTTSTTSGPGTTPSPVPTTST-TPVSKTSTSHLSVSKTTHSQPVTSDCHPL 104
            V TT  T  PT + T    TT  P  +T   T  S+   +  SV++ TH+ PVT +CHP 
Sbjct: 1687 VATTRPTPHPTGAQTQTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPVTRNCHPR 1746

Query: 105  CAWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAESHPEVNIEHLG 164
            C WTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRA+SHPEV+IEHLG
Sbjct: 1747 CTWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLG 1806

Query: 165  QVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCPVTS--VTPYGTSPTNALY 222
            QVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCPVTS  VT   T    A+ 
Sbjct: 1807 QVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCPVTSTPVTAPSTPSGRAIS 1866

Query: 223  PSLSTSMVSAS----VASTSVASSSVASSSVAYSTQT 255
            P+ STS    S    + +TS  S+   S++ A++T T
Sbjct: 1867 PTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTST 1903



 Score =  141 bits (355), Expect = 4e-33
 Identities = 93/234 (39%), Positives = 121/234 (51%), Gaps = 29/234 (12%)

Query: 45   PVPTTSTTSAPTTSTTSGPGT-----------TPSPVPTTSTTPVSKTS--TSHLSVSKT 91
            P  T  T S  T  TT  PGT           +P PVP TST+ +S T+  TS +S SK 
Sbjct: 1509 PSSTPGTVSLSTARTTPAPGTATSVKKTFSTPSPPPVPATSTSSMSTTTPGTSVVS-SKP 1567

Query: 92   THSQPVTSDC-HPLCAWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQC 150
            T ++P TS C   LC WT+W D  +P+PG +GGD +T+ N+   G   C  P  +   QC
Sbjct: 1568 TLTEPSTSSCLQELCTWTEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSV---QC 1624

Query: 151  RAESHPEVNIEHLGQVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGC----- 205
            RAES P   +  LGQ V CS  EGL+C N++Q  P  +C NYE+R+ CCET   C     
Sbjct: 1625 RAESFPNTPLADLGQDVICSHTEGLICLNKNQLPP--ICYNYEIRIQCCETVNVCRDITR 1682

Query: 206  -PVTSVTPYGT-SPTNA-LYPSLSTSMVSASVAS-TSVASSSVASSSVAYSTQT 255
             P T  T   T  PT A    + +T M SAS    T+ +     ++SV   T T
Sbjct: 1683 PPKTVATTRPTPHPTGAQTQTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHT 1736



 Score =  112 bits (281), Expect = 1e-24
 Identities = 74/222 (33%), Positives = 102/222 (45%), Gaps = 23/222 (10%)

Query: 47   PTTSTTSAP--TTSTTSGPGTTPSPV---PTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101
            PTT + S P    S+T  P   PS     P +S  P +  ++    +   + S P    C
Sbjct: 1326 PTTFSFSTPPLVVSSTHTPSNGPSSAHTGPPSSAWPTTAGTSPRTRLPTASASLPPV--C 1383

Query: 102  HPLCAWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAESHPEVNIE 161
               C W+ W DV  P  G   GD +T  N+   G ++C  P  +   +CRAE  P V + 
Sbjct: 1384 GEKCLWSPWMDVSRPGRGTDSGDFDTLENLRAHGYRVCESPRSV---ECRAEDAPGVPLR 1440

Query: 162  HLGQVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCPVTSVTPYGTSPT--- 218
             LGQ VQCS + GL CRN++Q     +C NY++RV CC TP  C  +S     T PT   
Sbjct: 1441 ALGQRVQCSPDVGLTCRNREQAS--GLCYNYQIRVQCC-TPLACSTSSSPAQTTPPTTSK 1497

Query: 219  -------NALYPSLSTSMVSASVASTSVASSSVASSSVAYST 253
                    +  PS +   VS S A T+ A  +  S    +ST
Sbjct: 1498 TTETRASGSSAPSSTPGTVSLSTARTTPAPGTATSVKKTFST 1539



 Score =  108 bits (269), Expect = 3e-23
 Identities = 139/611 (22%), Positives = 212/611 (34%), Gaps = 113/611 (18%)

Query: 197  LCCETPRGCPVTSVTPYGTSPTNALYPSLSTSMVSASVASTSVASSSVASSSVAYSTQTC 256
            +C +    CP +    Y  S       SLS   ++ SV    V        +    T  C
Sbjct: 696  VCTKPMTTCPKSMTYHYHVSTCQPTCRSLSEGDITCSVGFIPVDGCICPKGTFLDDTGKC 755

Query: 257  FCNVADRLYPAGSTIYRHRDLAGHCYYALCSQDCQVVRGVDSDCPSTTLPPAPATSPSIS 316
                    Y  GS I     +  H   A+C+            C    L      +P+  
Sbjct: 756  VQASNCPCYHRGSMIPNGESV--HDSGAICT------------CTHGKLSCIGGQAPAPV 801

Query: 317  TSEPVTELGCPNAVPPRKKGETWA--------------TPNCSEATCEGNNVISLRPRTC 362
             + P+    C NA P    G+T A              +P C       + +++     C
Sbjct: 802  CAAPMVFFDCRNATP----GDTGAGCQKSCHTLDMTCYSPQCVPGCVCPDGLVADGEGGC 857

Query: 363  PRVEKPTCANGYPAVKVAD--QDGC-----------CHHYQCQCVCSGWGDPHYITFDGT 409
               E   C +   + +     + GC           C    C   C+ +GD HY+TFDG 
Sbjct: 858  ITAEDCPCVHNEASYRAGQTIRVGCNTCTCDSRMWRCTDDPCLATCAVYGDGHYLTFDGQ 917

Query: 410  YYTFLDNCTYVLVQQIV----PVYGHFRVLVDNYFCGAEDGLSCPRSIILEYHQDRVVLT 465
             Y+F  +C Y LVQ            FRV+ +N  CG   G +C ++I +      + L+
Sbjct: 918  SYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTT-GTTCSKAIKIFLGGFELKLS 976

Query: 466  RKPVHGVMTNEIIFNNKVVSPGFRKNGI---VVSRIGVKMY---ATIPELGVQVMFSGLI 519
               V  + T+E    ++ V    R+ GI   V + IG+ +     T   + +   F G +
Sbjct: 977  HGKVEVIGTDE----SQEVPYTIRQMGIYLVVDTDIGLVLLWDKKTSIFINLSPEFKGRV 1032

Query: 520  FSV-----EVPFSKFANNTEG------------QCXXXXXXXTTPPAPCLPSPI------ 556
              +     ++  + FA  +              +          P  PC  +P       
Sbjct: 1033 CGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWKLSPSCPDALAPKDPCTANPFRKSWAQ 1092

Query: 557  --CQLILSKVFEPCHTVIPPLLFYEGCVFDRCHMT---DLDVVCSSLELYAALCASHDIC 611
              C ++    F  CH  + P  +YE CV D C      D +  C+++  YA  C    +C
Sbjct: 1093 KQCSILHGPTFAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLC 1152

Query: 612  IDWRGRTGHMCPFTC-------PADKVYQPCGPSNPSYCYGNDSASLGALPEAGPITEGC 664
            + W  RT  +CP  C         +  YQPCG      C       L  +       EGC
Sbjct: 1153 VSW--RTPSICPLFCDYYNPEGQCEWHYQPCGVPCLRTCRNPRGDCLRDVWG----LEGC 1206

Query: 665  F--CPEGMTLFSTSAQVCVPTGC------PRCLGPHGEPVKVGHTVGMD--CQECTCEAA 714
            +  CP    +F      CV T C      PRC   HG+  + G  V  D  CQ C C   
Sbjct: 1207 YPKCPPEAPIFDEDKMQCVAT-CPTPPLPPRC-HVHGKSYRPGAVVPSDKNCQSCLCTER 1264

Query: 715  TWTLTCRPKLC 725
                T + + C
Sbjct: 1265 GVECTYKAEAC 1275



 Score =  106 bits (265), Expect = 1e-22
 Identities = 135/538 (25%), Positives = 199/538 (36%), Gaps = 89/538 (16%)

Query: 386 CHHYQCQCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVLVDNYFCGAED 445
           C    C   CS  G  H+ TFDG  YT   +C+YVL +        F VL +   CG  D
Sbjct: 425 CQEVPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDS--SAFTVLAELRRCGLTD 482

Query: 446 GLSCPRSIILEYHQDRVVLTRKPVHGVMTNEIIFNNKVVSPG---FRKNGIVV---SRIG 499
             +C +S+ L     + V+  K    V  N+I     + +     FR +   +   + +G
Sbjct: 483 SETCLKSVTLSLDGVQTVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLG 542

Query: 500 VKMYATI-----------PELGVQVM-------------FSGLIFSVEVPFSKFANN--T 533
           +++   +           P+L  Q               F  L   VE   + F N   T
Sbjct: 543 LQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKT 602

Query: 534 EGQCXXXXXXXTTPPAPCLPSP-ICQLILSKV------FEPCHTVIPPLLFYEGCVFDRC 586
           +  C         P +  + +    Q   S++      F  CH  + P  +Y  C+FD C
Sbjct: 603 QAACPNIRNSFEDPCSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTC 662

Query: 587 HM-TDLDVVCSSLELYAALCASHDICI-DWRGRTGHMCPFTCPADKVY----QPCGPSNP 640
           +     D +C++L  Y   CA+  + +  WR         TCP    Y      C P+  
Sbjct: 663 NCERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVSTCQPTCR 722

Query: 641 SYCYGNDSASLGALPEAGPITEGCFCPEGMTLFSTSAQVCVPTGCPRCLGPHGEPVKVGH 700
           S   G+ + S+G +P      +GC CP+G T    + +    + CP C    G  +  G 
Sbjct: 723 SLSEGDITCSVGFIP-----VDGCICPKG-TFLDDTGKCVQASNCP-CY-HRGSMIPNGE 774

Query: 701 TVGMDCQECTCEAATWTLTCRPKLCPLPP-ACPLPGFVPVPAAP-QAGQCCPQYSC---- 754
           +V      CTC      L+C     P P  A P+  F    A P   G  C Q SC    
Sbjct: 775 SVHDSGAICTCTHG--KLSCIGGQAPAPVCAAPMVFFDCRNATPGDTGAGC-QKSCHTLD 831

Query: 755 -ACNTSRCPKPVGCPEGARAIPTYQEGACCPVQNCSWTVCSINGTLYQPGAVVSSSLCET 813
             C + +C     CP+G   +    EG C   ++C    C  N   Y+ G  +    C T
Sbjct: 832 MTCYSPQCVPGCVCPDG---LVADGEGGCITAEDCP---CVHNEASYRAGQTIRVG-CNT 884

Query: 814 CRCELPGGPPSDAFVVSCETQICNTHCPV-------GFEYQEQS--GQCCGTCVQVAC 862
           C C        D+ +  C    C   C V        F+ Q  S  G C  T VQ  C
Sbjct: 885 CTC--------DSRMWRCTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHC 934



 Score = 92.8 bits (229), Expect = 2e-18
 Identities = 94/377 (24%), Positives = 140/377 (37%), Gaps = 69/377 (18%)

Query: 394 VCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVLVDNYFCGAEDGLSCPRSI 453
           VCS WG  HY TFDG  + F   C YV  +     Y  F + +      A   LS    +
Sbjct: 80  VCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQESAAPTLS---RV 136

Query: 454 ILEYHQDRVVLTRKPVHGVMTNEIIFNNKVVSPGFRKNGIVVSRIGVKMYATIP-ELGVQ 512
           +++     + LT+          ++ N   V   F ++G+++ +     Y  +   LG+ 
Sbjct: 137 LMKVDGVVIQLTK--------GSVLVNGHPVLLPFSQSGVLIQQSS--SYTKVEARLGLV 186

Query: 513 VMFS---GLIFSVEVPFSKFANNTEGQCXXXXXXXTT----------------------- 546
           +M++    L+  ++   +K+AN T G C                                
Sbjct: 187 LMWNHDDSLLLELD---TKYANKTCGLCGDFNGMPVVSELLSHNTKLTPMEFGNLQKMDD 243

Query: 547 PPAPC---LPSP---------ICQLIL-SKVFEPCHTVIPPLLFYEGCVFDRCHMTDLDV 593
           P   C   +P P         IC+ +L  ++F  C  ++    + E C  D C   D D+
Sbjct: 244 PTEQCQDPVPEPPRNCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDL 303

Query: 594 ---VCSSLELYAALCA-SHDICIDWRGRTGHMCPFTCPADKVYQPCGPSNPSYCYGNDSA 649
              VC +L  Y+  C  +  +  DWRG     CP  CP +  Y  C       C  N   
Sbjct: 304 LSCVCHTLAEYSRQCTHAGGLPQDWRGPD--FCPQKCPNNMQYHECRSPCADTC-SNQEH 360

Query: 650 SLGALPEAGPITEGCFCPEGMTLFSTSAQVCVPTGCPRCLGPHGEPVKVGHTVGMDCQEC 709
           S            GCFCPEG  L       CVP     C+  +G     G T   DC  C
Sbjct: 361 SRACEDHC---VAGCFCPEGTVLDDIGQTGCVPVSKCACV-YNGAAYAPGATYSTDCTNC 416

Query: 710 TCEAATWTLTCRPKLCP 726
           TC    W  +C+   CP
Sbjct: 417 TCSGGRW--SCQEVPCP 431



 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 35/76 (46%), Positives = 42/76 (55%), Gaps = 1/76 (1%)

Query: 45   PVPTTSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDCHPL 104
            PVPTTST SAPTTS TS P T+ +  PT+STT    TST+    S TT S   ++   P 
Sbjct: 1937 PVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPT 1996

Query: 105  CAWTKWFDVDFPSPGP 120
             + T       PSP P
Sbjct: 1997 TSTTSGPGTT-PSPVP 2011



 Score = 57.8 bits (138), Expect = 5e-08
 Identities = 31/53 (58%), Positives = 34/53 (64%), Gaps = 1/53 (1%)

Query: 47   PTTSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTS 99
            PTT TTSA   STTSGPG TPSPVPTTST     TS +    + TT S P +S
Sbjct: 1915 PTTRTTSASPASTTSGPGNTPSPVPTTSTISAPTTSITSAPTTSTT-SAPTSS 1966



 Score = 57.0 bits (136), Expect = 9e-08
 Identities = 26/27 (96%), Positives = 26/27 (96%)

Query: 47   PTTSTTSAPTTSTTSGPGTTPSPVPTT 73
            P TSTTSAPTTSTTSGPGTTPSPVPTT
Sbjct: 1987 PQTSTTSAPTTSTTSGPGTTPSPVPTT 2013



 Score = 54.3 bits (129), Expect = 6e-07
 Identities = 27/57 (47%), Positives = 36/57 (63%)

Query: 42   NLCPVPTTSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVT 98
            ++   PTTSTTSAPT+STTS P T+ +  PT+STT   +TST+    + TT     T
Sbjct: 1950 SITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPGTT 2006



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 46/146 (31%), Positives = 54/146 (36%), Gaps = 17/146 (11%)

Query: 698 VGHTVGMDCQECTCEAATWTLTCRPKLCPLPPACPLPGFVPVPAAPQAGQCCPQ-YSCAC 756
           V HT+    ++CT           P  CP    CP         +P A  C  Q +S AC
Sbjct: 307 VCHTLAEYSRQCTHAGGLPQDWRGPDFCP--QKCPNNMQYHECRSPCADTCSNQEHSRAC 364

Query: 757 NTSRCPKPVGCPEGARAIPTYQEGACCPVQNCSWTVCSINGTLYQPGAVVSSSLCETCRC 816
               C     CPEG       Q G C PV  C+   C  NG  Y PGA  S+  C  C C
Sbjct: 365 E-DHCVAGCFCPEGTVLDDIGQTG-CVPVSKCA---CVYNGAAYAPGATYSTD-CTNCTC 418

Query: 817 ELPGGPPSDAFVVSCETQICNTHCPV 842
              GG        SC+   C   C V
Sbjct: 419 S--GGR------WSCQEVPCPGTCSV 436



 Score = 40.0 bits (92), Expect = 0.012
 Identities = 30/129 (23%), Positives = 43/129 (33%), Gaps = 18/129 (13%)

Query: 251  YSTQTCFCNVADRLYPAGSTIYRHRDLAGHCYYALCSQDCQVVRGVDSDCPSTTLPPA-- 308
            Y  + C C    + +  G  IY   D  G C  A C  +  + R V    P+T +PP   
Sbjct: 1270 YKAEACVCTYNGQRFHPGDVIYHTTDGTGGCISARCGANGTIERRVYPCSPTTPVPPTTF 1329

Query: 309  PATSPSISTSEPVTELGCPNAVPPRKKGETWATPNCSEATCEGNNVISLRPRTCPRVEKP 368
              ++P +  S   T    P++         W T                   T PR   P
Sbjct: 1330 SFSTPPLVVSSTHTPSNGPSSAHTGPPSSAWPT----------------TAGTSPRTRLP 1373

Query: 369  TCANGYPAV 377
            T +   P V
Sbjct: 1374 TASASLPPV 1382



 Score = 38.5 bits (88), Expect = 0.034
 Identities = 20/53 (37%), Positives = 29/53 (54%)

Query: 51   TTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDCHP 103
            TT+  TTSTTS P T+ +   TTSTT      T+    ++TT + P ++   P
Sbjct: 1879 TTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931



 Score = 36.2 bits (82), Expect = 0.17
 Identities = 27/74 (36%), Positives = 36/74 (48%), Gaps = 1/74 (1%)

Query: 47   PTTSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDCHPLCA 106
            PT ST+S   + TT+   T+ +  P TSTT    TST+    ++TT S P T       A
Sbjct: 1867 PTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTT-SAPTTRTTSASPA 1925

Query: 107  WTKWFDVDFPSPGP 120
             T     + PSP P
Sbjct: 1926 STTSGPGNTPSPVP 1939



 Score = 35.0 bits (79), Expect = 0.38
 Identities = 62/297 (20%), Positives = 98/297 (32%), Gaps = 82/297 (27%)

Query: 761  CPKPVGCPEGARAIP---TYQEGACCPVQNCSWTVCSINGTLYQPGAVVSSSLCETCRCE 817
            CP  +   +   A P   ++ +  C  +   ++  C  +    +P     + + + C C+
Sbjct: 1071 CPDALAPKDPCTANPFRKSWAQKQCSILHGPTFAACHAH---VEPARYYEACVNDACACD 1127

Query: 818  LPGGPPSDAFVVSCETQICN-----------THCPVGFEYQEQSGQC------CGTCVQV 860
              G        V+   Q C+           + CP+  +Y    GQC      CG    V
Sbjct: 1128 SGGDCECFCTAVAAYAQACHEVGLCVSWRTPSICPLFCDYYNPEGQCEWHYQPCG----V 1183

Query: 861  ACVTNTSKSPAHLFYPGETWSDAGNHCVTHQCEKHQDGLVVVTTKKACPPLSCSLDEARM 920
             C+  T ++P                     C +   GL     K  CPP +   DE +M
Sbjct: 1184 PCL-RTCRNPRG------------------DCLRDVWGLEGCYPK--CPPEAPIFDEDKM 1222

Query: 921  SKDGCCRFCPPPPPPYQNQSTCAVYHRSLIIQQQGCSSSEPVRLAYCRGNCGDSSSMYSL 980
                C   CP PP P      C V+ +S            P  +     NC   S + + 
Sbjct: 1223 Q---CVATCPTPPLP----PRCHVHGKSY----------RPGAVVPSDKNC--QSCLCTE 1263

Query: 981  EGNTVEHRCQCCQELRTSLR----NVTLHCTDGSSRAFSYTEVEECGCMGRRCPAPG 1033
             G    ++ + C       R    +V  H TDG+            GC+  RC A G
Sbjct: 1264 RGVECTYKAEACVCTYNGQRFHPGDVIYHTTDGTG-----------GCISARCGANG 1309



 Score = 32.0 bits (71), Expect = 3.2
 Identities = 42/138 (30%), Positives = 52/138 (37%), Gaps = 29/138 (21%)

Query: 703  GMDCQECTCEA-ATWTLTCRPK-LCP---LPPACPLPGFVPVPAAPQAGQCCPQY----- 752
            G DC EC C A A +   C    LC     P  CPL      P     GQC   Y     
Sbjct: 1129 GGDC-ECFCTAVAAYAQACHEVGLCVSWRTPSICPLFCDYYNPE----GQCEWHYQPCGV 1183

Query: 753  ----SCACNTSRCPKPV----GC-PEGARAIPTYQEGACCPVQNCSWTV----CSINGTL 799
                +C      C + V    GC P+     P + E     V  C        C ++G  
Sbjct: 1184 PCLRTCRNPRGDCLRDVWGLEGCYPKCPPEAPIFDEDKMQCVATCPTPPLPPRCHVHGKS 1243

Query: 800  YQPGAVV-SSSLCETCRC 816
            Y+PGAVV S   C++C C
Sbjct: 1244 YRPGAVVPSDKNCQSCLC 1261


>gi|89191868 von Willebrand factor preproprotein [Homo sapiens]
          Length = 2813

 Score =  210 bits (534), Expect = 7e-54
 Identities = 184/720 (25%), Positives = 267/720 (37%), Gaps = 155/720 (21%)

Query: 333  RKKGETWATPN-CSEATCE--GNNVISLRPRTCPRVEKPTCANGYPAVKVADQDGCCHHY 389
            ++ G+ W  P+ C   TC+  G  ++      C R  +P+C N    VKV +  GC   +
Sbjct: 1887 KRPGDVWTLPDQCHTVTCQPDGQTLLKSHRVNCDRGLRPSCPNSQSPVKVEETCGC--RW 1944

Query: 390  QCQCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVLVDNYFCGAEDGLSC 449
             C CVC+G    H +TFDG  +    +C+YVL Q          V++ N  C       C
Sbjct: 1945 TCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQ---DLEVILHNGACSPGARQGC 2001

Query: 450  PRSIILEYHQDRVVLTRKPVHGVMTNEIIFNNKVVSPGFRKNGIVVSRIGVKMYAT-IPE 508
             +SI +++    V L     H  M  E+  N ++VS  +    + V+  G  M+      
Sbjct: 2002 MKSIEVKHSALSVEL-----HSDM--EVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNH 2054

Query: 509  LGVQVMFS--GLIFSVEVPFSKFANNTEGQCXXXXXXXTT-------------------- 546
            LG    F+     F +++    FA+ T G C                             
Sbjct: 2055 LGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEW 2114

Query: 547  ----PPAPCLP----------SPICQLILSKVFEPCHTVIPPLLFYEGCVFDRCHMTDLD 592
                P   C P          S  CQ++L  +F  CH V+ P  FY  C  D CH    +
Sbjct: 2115 TVQRPGQTCQPILEEQCLVPDSSHCQVLLLPLFAECHKVLAPATFYAICQQDSCHQ---E 2171

Query: 593  VVCSSLELYAALCASHDICIDWRGRTGHMCPFTCPADKVYQPCGPSNPSYCYGNDSASLG 652
             VC  +  YA LC ++ +C+DW  RT   C  +CP   VY  C    P +C GN S S G
Sbjct: 2172 QVCEVIASYAHLCRTNGVCVDW--RTPDFCAMSCPPSLVYNHCEHGCPRHCDGNVS-SCG 2228

Query: 653  ALPEAGPITEGCFCPEGMTLFSTSAQVCVP-TGCPRCLG-------------PHGEPVKV 698
              P     +EGCFCP    +   S   CVP   C +C+G             P  +P ++
Sbjct: 2229 DHP-----SEGCFCPPDKVMLEGS---CVPEEACTQCIGEDGVQHQFLEAWVPDHQPCQI 2280

Query: 699  -----GHTVGMDCQEC---------TCEAA-----------TWTLTCRPKLCPLPPA--C 731
                 G  V    Q C          CE A            +   C P  C LPP   C
Sbjct: 2281 CTCLSGRKVNCTTQPCPTAKAPTCGLCEVARLRQNADQCCPEYECVCDPVSCDLPPVPHC 2340

Query: 732  PLPGFVPVPAAPQAGQCCPQYSCACNTSRCPK--PVGCPEGARAIPTYQEGACCPVQNCS 789
               G  P    P  G+C P ++CAC    C +  P  CP     +PT ++  CC    C+
Sbjct: 2341 E-RGLQPTLTNP--GECRPNFTCACRKEECKRVSPPSCP--PHRLPTLRKTQCCDEYECA 2395

Query: 790  WT--------------------------------VCSINGTLYQPGAVVSSSLCETCRCE 817
                                              VC    T+Y  G       C+ C C 
Sbjct: 2396 CNCVNSTVSCPLGYLASTATNDCGCTTTTCLPDKVCVHRSTIYPVGQFWEEG-CDVCTCT 2454

Query: 818  LPGGPPSDAFVVSCETQICNTHCPVGFEYQEQSGQCCGTCVQVAC--VTNTSKSPAHLFY 875
                      V  C  + C   C  GF Y    G+CCG C+  AC  VT + +  +   +
Sbjct: 2455 DMEDAVMGLRVAQCSQKPCEDSCRSGFTYVLHEGECCGRCLPSACEVVTGSPRGDSQSSW 2514

Query: 876  P--GETWSDAGNHCVTHQCEKHQDGLVVVTTKKACP----PLSCSLDEARMSKDGCCRFC 929
               G  W+   N C+ ++C + ++ + +     +CP    P+  S  +       CC  C
Sbjct: 2515 KSVGSQWASPENPCLINECVRVKEEVFIQQRNVSCPQLEVPVCPSGFQLSCKTSACCPSC 2574



 Score =  138 bits (348), Expect = 2e-32
 Identities = 89/279 (31%), Positives = 125/279 (44%), Gaps = 26/279 (9%)

Query: 761  CPK---PVGCPEGARAIPTYQEGACCPVQNCS-WTVCSINGTLYQPGAVVSSSLCETCRC 816
            CP+   PV CP G +   + +  ACCP   C     C +NGT+  PG  V   +C TCRC
Sbjct: 2549 CPQLEVPV-CPSGFQL--SCKTSACCPSCRCERMEACMLNGTVIGPGKTVMIDVCTTCRC 2605

Query: 817  ELPGGPPSDAFVVSCETQICNTHCPVGFEYQEQSGQCCGTCVQVACVTNTSKSPAHLFYP 876
             +  G  S  F + C    CN  CP+G++ +  +G+CCG C+  AC              
Sbjct: 2606 MVQVGVIS-GFKLECRKTTCNP-CPLGYKEENNTGECCGRCLPTACTIQLRGGQIMTLKR 2663

Query: 877  GETWSDAGNHCVTHQCEKHQDGLVVVTTK-KACPPLS---CSLDEARMSK--DGCCRFCP 930
             ET  D    C TH C+ ++ G      +   CPP     C  +  ++ K    CC  C 
Sbjct: 2664 DETLQDG---CDTHFCKVNERGEYFWEKRVTGCPPFDEHKCLAEGGKIMKIPGTCCDTCE 2720

Query: 931  PPPPPYQNQSTCAVYHRSLIIQQQGCSSSEPVRLAYCRGNCGDSSSMYSLEGNTVEHRCQ 990
             P     N  T  + +    ++   C S   V + YC+G C  S +MYS++ N V+ +C 
Sbjct: 2721 EPEC---NDITARLQY----VKVGSCKSEVEVDIHYCQGKCA-SKAMYSIDINDVQDQCS 2772

Query: 991  CCQELRTSLRNVTLHCTDGSSRAFSYTEVEECGCMGRRC 1029
            CC   RT    V LHCT+GS          EC C  R+C
Sbjct: 2773 CCSPTRTEPMQVALHCTNGSVVYHEVLNAMECKCSPRKC 2811



 Score =  102 bits (253), Expect = 3e-21
 Identities = 136/544 (25%), Positives = 204/544 (37%), Gaps = 107/544 (19%)

Query: 282  YYALCSQDCQVVRGVDSDCPSTTLPPAPATSP-------SISTSEPVTELGCPNAVPPRK 334
            ++ +C  +   +    S  P + LP A  +SP       S+S   P+ +L CP A   R 
Sbjct: 725  HHTMCYCEDGFMHCTMSGVPGSLLPDAVLSSPLSHRSKRSLSCRPPMVKLVCP-ADNLRA 783

Query: 335  KG-ETWATPNCSEATCEGNNVIS---------LRPRTCPRVEKPTCAN------------ 372
            +G E   T    +  C     +S              C  +E+  C +            
Sbjct: 784  EGLECTKTCQNYDLECMSMGCVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGETVK 843

Query: 373  -GYPAVKVADQDGCCHHYQCQCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVY-G 430
             G       D+   C  + C   CS  G  HY+TFDG  Y F   C YVLVQ       G
Sbjct: 844  IGCNTCVCRDRKWNCTDHVCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPG 903

Query: 431  HFRVLVDNYFCGAEDGLSCPR--SIILEYHQ----DRVVLTRKPVHGVMTNEIIFNNKVV 484
             FR+LV N  C +   + C +  +I++E  +    D  V  ++P+      E++ + + +
Sbjct: 904  TFRILVGNKGC-SHPSVKCKKRVTILVEGGEIELFDGEVNVKRPMKDETHFEVVESGRYI 962

Query: 485  SPGFRKNGIVV----SRIGVKMYATIPE--LGVQVMFSGLI--------FSVEVPFSKFA 530
                 K   VV      I V +  T  E   G+   F G+           VE     F 
Sbjct: 963  ILLLGKALSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFG 1022

Query: 531  NN--TEGQCXXXXXXXT-TPPAPC--------LPSPICQLILSKVFEPCHTVIPPLLFYE 579
            N+     QC         + PA C        +    C+++ S VF+ C+ ++ P  + +
Sbjct: 1023 NSWKVSSQCADTRKVPLDSSPATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVDPEPYLD 1082

Query: 580  GCVFDRC---HMTDLDVVCSSLELYAALCASHDICIDWRGRTGHMCPFTCPADKV----- 631
             C++D C    + D    C ++  YA +CA H   + W  RT  +CP +C    +     
Sbjct: 1083 VCIYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVVTW--RTATLCPQSCEERNLRENGY 1140

Query: 632  -----YQPCGPSNPSYCYGNDSASLGALPEAGPI--TEGC--FCPEGMTLFSTSAQVCV- 681
                 Y  C P+    C   +       P A P+   EGC   CP G  L     Q CV 
Sbjct: 1141 ECEWRYNSCAPACQVTCQHPE-------PLACPVQCVEGCHAHCPPGKIL-DELLQTCVD 1192

Query: 682  PTGCPRC-----LGPHGEPVKVGHTVGMDCQECTCEAATWTLTCRPKLCPLPPACPLPGF 736
            P  CP C         G+ V +  +    CQ C C+     LTC         AC  PG 
Sbjct: 1193 PEDCPVCEVAGRRFASGKKVTLNPSDPEHCQICHCDVV--NLTCE--------ACQEPGG 1242

Query: 737  VPVP 740
            + VP
Sbjct: 1243 LVVP 1246



 Score = 89.0 bits (219), Expect = 2e-17
 Identities = 80/293 (27%), Positives = 109/293 (37%), Gaps = 58/293 (19%)

Query: 557 CQLILSKVFEPCHTVIPPLLFYEGCVFDRCHMTD-LDVVCSSLELYAALCASHDICIDWR 615
           C ++ S  FE CH  + PL +   C +D C  +D  + +C +L  YAA CA   + + WR
Sbjct: 584 CAVLTSPTFEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALASYAAACAGRGVRVAWR 643

Query: 616 --GRTGHMCPFTCPADKVYQPCG-PSN---PSYCYGNDSASLGALPEAGPITEGCFCPEG 669
             GR    C   CP  +VY  CG P N    S  Y ++  +   L       EGCFCP G
Sbjct: 644 EPGR----CELNCPKGQVYLQCGTPCNLTCRSLSYPDEECNEACL-------EGCFCPPG 692

Query: 670 MTLFSTSAQVCVPTGCPRCL--GPHGEPVKV--GHTVGMDCQE----CTCEA-------- 713
             L+      CVP     C   G   +P  +   H     C++    CT           
Sbjct: 693 --LYMDERGDCVPKAQCPCYYDGEIFQPEDIFSDHHTMCYCEDGFMHCTMSGVPGSLLPD 750

Query: 714 ----------ATWTLTCRPKLCPLPPACPLPGFVPVPAAPQAGQCCPQYSCACNTSRCPK 763
                     +  +L+CRP +  L   CP           +  + C  Y   C +  C  
Sbjct: 751 AVLSSPLSHRSKRSLSCRPPMVKL--VCPADNL--RAEGLECTKTCQNYDLECMSMGCVS 806

Query: 764 PVGCPEGARAIPTYQEGACCPVQNCSWTVCSINGTLYQPGAVVSSSLCETCRC 816
              CP G        E  C  ++ C    C   G  Y PG  V    C TC C
Sbjct: 807 GCLCPPGM----VRHENRCVALERCP---CFHQGKEYAPGETVKIG-CNTCVC 851



 Score = 60.8 bits (146), Expect = 6e-09
 Identities = 53/174 (30%), Positives = 73/174 (41%), Gaps = 17/174 (9%)

Query: 557 CQLILS-KVFEPCHTVIPPLLFYEGCVFDRCHMTD-LDVVCSSLELYAALCASHDICIDW 614
           CQL+ S  VF  CH ++ P  F   C    C     L+  C +L  YA  CA   + +  
Sbjct: 225 CQLLKSTSVFARCHPLVDPEPFVALCEKTLCECAGGLECACPALLEYARTCAQEGMVL-- 282

Query: 615 RGRTGHM-CPFTCPADKVYQPCGPSNPSYCYGNDSASLGALPEAGPITEGCFCPEGMTLF 673
            G T H  C   CPA   Y+ C       C    S  +  + +   + +GC CPEG  L 
Sbjct: 283 YGWTDHSACSPVCPAGMEYRQCVSPCARTC---QSLHINEMCQERCV-DGCSCPEGQLL- 337

Query: 674 STSAQVCVP-TGCPRCLGPHGEPVKVGHTVGMDCQECTCEAATWTLTCRPKLCP 726
                +CV  T CP C+   G+    G ++  DC  C C  + W   C  + CP
Sbjct: 338 --DEGLCVESTECP-CVHS-GKRYPPGTSLSRDCNTCICRNSQW--ICSNEECP 385



 Score = 38.5 bits (88), Expect = 0.034
 Identities = 18/68 (26%), Positives = 31/68 (45%), Gaps = 2/68 (2%)

Query: 386 CHHYQCQCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVLVDNYFCGAED 445
           C + +C   C   G  H+ +FD  Y+TF   C Y+L +        F ++++   C  + 
Sbjct: 379 CSNEECPGECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQD--HSFSIVIETVQCADDR 436

Query: 446 GLSCPRSI 453
              C RS+
Sbjct: 437 DAVCTRSV 444



 Score = 34.3 bits (77), Expect = 0.64
 Identities = 32/125 (25%), Positives = 44/125 (35%), Gaps = 22/125 (17%)

Query: 288  QDCQVVRGVDSDCPSTTLPPAPATSPSISTSE------------PVTELGCPNA---VPP 332
            Q C  + G   +C  TT P   A +P+    E            P  E  C      +PP
Sbjct: 2279 QICTCLSGRKVNC--TTQPCPTAKAPTCGLCEVARLRQNADQCCPEYECVCDPVSCDLPP 2336

Query: 333  RKKGETWATPNCSE-ATCEGNNVISLRPRTCPRVEKPTCA-NGYPAVKVADQDGCCHHYQ 390
                E    P  +    C  N   + R   C RV  P+C  +  P ++      CC  Y+
Sbjct: 2337 VPHCERGLQPTLTNPGECRPNFTCACRKEECKRVSPPSCPPHRLPTLRKTQ---CCDEYE 2393

Query: 391  CQCVC 395
            C C C
Sbjct: 2394 CACNC 2398



 Score = 31.2 bits (69), Expect = 5.4
 Identities = 33/145 (22%), Positives = 47/145 (32%), Gaps = 28/145 (19%)

Query: 809 SLCETCRCELPGG-----PPSDAFVVSCETQ-----------ICNTHCPVGFEYQEQSGQ 852
           +LCE   CE  GG     P    +  +C  +            C+  CP G EY++    
Sbjct: 248 ALCEKTLCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSP 307

Query: 853 CCGTC--------VQVACVTNTSKSPAHLFYPGETWSDAGNHCVTHQCEKHQDGLVVVTT 904
           C  TC         Q  CV   S     L   G         CV H  +++  G    + 
Sbjct: 308 CARTCQSLHINEMCQERCVDGCSCPEGQLLDEGLCVESTECPCV-HSGKRYPPG---TSL 363

Query: 905 KKACPPLSCSLDEARMSKDGCCRFC 929
            + C    C   +   S + C   C
Sbjct: 364 SRDCNTCICRNSQWICSNEECPGEC 388


>gi|239755545 PREDICTED: otogelin isoform 1 [Homo sapiens]
          Length = 2852

 Score =  165 bits (417), Expect = 2e-40
 Identities = 156/644 (24%), Positives = 235/644 (36%), Gaps = 187/644 (29%)

Query: 545  TTPPAPCLPSPICQLILSKVFEPCHTVIPPLLFYEGCVFDRCHMTDLDVVCSSLELYAAL 604
            TT  +PCL     +++ ++ F  CH  +PP  F E  + D  ++      C +L +Y A+
Sbjct: 2229 TTDCSPCL-----RMVSNRTFSACHRFVPPESFCELWIRDTKYVQQ---PCVALTVYVAM 2280

Query: 605  CASHDICIDWRGRTGHMCPFTCPADKVYQPC---------------GPSNPSY------- 642
            C    +CI+WR      CPF C +D  YQ C               GP +P +       
Sbjct: 2281 CHKFHVCIEWR--RSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEG 2338

Query: 643  CYGNDSASLG------ALPEAG------------------------------------PI 660
            C  ++   L        +PEA                                     P+
Sbjct: 2339 CVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPV 2398

Query: 661  TEGCFCP--EGMTLFSTSAQVCVPTGCPRCLGPH-----------GEPVKVGHTVGMDCQ 707
              GC  P  E    F   A + +PT  P CLG                 + GH +    Q
Sbjct: 2399 DLGCPSPRPESCLRFGEVA-LLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQ 2457

Query: 708  ECTCEAATWTLTCRPKLCP--LPPAC------------------------PLPGFVPVPA 741
            E +C   +++  C P LC   L P+C                          P  +P   
Sbjct: 2458 EDSC-CPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQ 2516

Query: 742  APQA--------GQCCPQYSCACNTSRCPKPVGCPEGARAIPTYQEGACCPVQNCS---- 789
              +A          CCP Y C C   RCP+ V C  G   +  +    CCP ++C     
Sbjct: 2517 EGEALTVHRNTTELCCPLYQCVCENFRCPQ-VQCGLGTALVEVWSPDRCCPYKSCECDCD 2575

Query: 790  ---------W--------------TVC--------------SINGTLYQPGAVV----SS 808
                     W               VC              S    + QPG  V    + 
Sbjct: 2576 TIPVPRCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSAD 2635

Query: 809  SLCETCRCELPGGPPSDAFVVSCETQICNTHCPVGFEYQEQS--GQCCGTCVQVACVTNT 866
             +C T RC     P ++ + ++  + +C+ HC    EY+       CCG+C  V+C+   
Sbjct: 2636 GVCHTSRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTF 2695

Query: 867  SKSPAHLFYPGETWSDAGNHCVTHQCEKHQDGLVVVTTKKACPPLS---CSLDEARM--S 921
                  LF PG +W      C  H C     G V+V +  +CPPL+   C+     +  S
Sbjct: 2696 PNGTTSLFLPGASWI---ADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPS 2752

Query: 922  KDGCCRFCPPPPPPYQNQSTCAVYHRSLIIQQQGCSSSEPVRLAYCRGNCGDSSSMYSLE 981
             +GCCR C       ++  +C      + I++  C SS PV L  C G C  S+S+Y+  
Sbjct: 2753 LEGCCRTCK------EDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRC-PSASIYNYN 2805

Query: 982  GNTVEHRCQCCQELRTSLRNVTLHC-TDGSSRAFSYTEVEECGC 1024
             NT    C+CC+E+    R+V L C T+ +   ++  E  +C C
Sbjct: 2806 INTYARFCKCCREVGLQRRSVQLFCATNATWVPYTVQEPTDCAC 2849



 Score =  108 bits (269), Expect = 3e-23
 Identities = 121/490 (24%), Positives = 178/490 (36%), Gaps = 81/490 (16%)

Query: 386 CHHYQCQCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVLVDNYFCGAED 445
           C    C   CS  GD H+ TFDG  YTF   C Y+L +      G F V + N  CG   
Sbjct: 432 CSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSS--GTFTVTLQNAPCGLNQ 489

Query: 446 GLSCPRSIILEYHQD---RVVLTRKPVHGVMTNEIIFNNKVVSPGFRKNGIVVSRIGVKM 502
             +C +S+ +  HQD   +V LT+        + ++F+   + P +  +   + R+    
Sbjct: 490 DGACVQSVSVILHQDPRRQVTLTQAG------DVLLFDQYKIIPPYTDDAFEIRRLSSVF 543

Query: 503 YATIPELGVQVMFS--GLIFSVEVPFSKFANNTEGQCXXXXXXX------------TTPP 548
                 +GV+V++   GL   ++V   ++  +T G C                   +TP 
Sbjct: 544 LRVRTNVGVRVLYDREGLRLYLQVD-QRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQ 602

Query: 549 ---------APCLP----SPI----------------CQLILSKVFEPCHTVIPPLLFYE 579
                    + C P    SP+                C ++  ++F PC   + P+ ++E
Sbjct: 603 LFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFE 662

Query: 580 GCVFDRCHMTDLDVVCSSLELYAALCASHDICIDWRGRTGHMCPFTCPADKVYQPCGPSN 639
            C  D C       +C++L  YA LC  H + +D+R R    C  +C A K Y PC    
Sbjct: 663 QCRRDACRCGQ-PCLCATLAHYAHLCRRHGLPVDFRARL-PACALSCEASKEYSPCVAPC 720

Query: 640 PSYCYGNDSASLGALPEAG-------PITEGCFCPEGMTLFSTSAQVCVPTGCPRCLGPH 692
              C   D AS  A    G          EGC CP   T   T A +CVP     C    
Sbjct: 721 GRTC--QDLASPEACGVDGGDDLSRDECVEGCACPPD-TYLDTQADLCVPRNQCSC-HFQ 776

Query: 693 GEPVKVGHTVGMDCQECTCEAATWTLTCR--PKLCPLPPACPLPGFVPVPAAPQAGQCCP 750
           G     G +       C C+    +   R     CP          +         + C 
Sbjct: 777 GVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCE 836

Query: 751 QYSCACNTSR---CPKPVGCPEGARAIPTYQEGACCPVQNCSWTVCSINGTLYQPGAVVS 807
           Q     + S    C     CP+G          AC   + C    C+  G  Y PG  V 
Sbjct: 837 QQLLNLSVSARGPCLSGCACPQGL----LRHGDACFLPEECP---CTWKGKEYFPGDQVM 889

Query: 808 SSLCETCRCE 817
           S  C TC C+
Sbjct: 890 SP-CHTCVCQ 898



 Score =  105 bits (263), Expect = 2e-22
 Identities = 187/773 (24%), Positives = 267/773 (34%), Gaps = 160/773 (20%)

Query: 304  TLPPAPATSPSISTSEPVTELGCPNAVPPRKKGETWATP----NCSEATC-EGNNVISLR 358
            T  P+  ++P++S  E + E     A        T   P    +C    C EG  +   +
Sbjct: 1946 TTEPSGRSAPALSIVEGLAEA---LATTTEANTSTTCVPIAEQDCVRHICLEGQLIRVNQ 2002

Query: 359  PRTCPR-VEKPTCANGYPAVKVADQDGCCHHYQCQCVCSGWGDPHYITFDGTYYTFLDNC 417
             + CP+    P C     AV+V   D CC  ++C C CS + D  ++TFDG++       
Sbjct: 2003 SQHCPQGAAPPRCGILGLAVRVGG-DRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEA 2061

Query: 418  TYVLVQQIVPVYGHFRVLVDNYFCGAEDGLSCPRSIILEYHQDRVVLTRKPVHGVMTNEI 477
             Y+L Q    +     V V +        L+ P   ++  +   +       H V  +  
Sbjct: 2062 IYILSQSPDEM---LTVHVLDCKSANLGHLNWPPFCLVMLNMTHL------AHQVTIDR- 2111

Query: 478  IFNNKV------VSPGFRKNGIVVSRIG-VKMYATIPELGVQVMFSGLIFSVEVPFSKFA 530
             FN KV      V P   + G  +   G + M  T  ++ +Q + S  +  VE   +  A
Sbjct: 2112 -FNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKA 2170

Query: 531  --NNTEGQCXXXXXXXTT-----------PPAPCLPSPICQLILSKV----FEP--CHTV 571
              +   G C        T            PAP L S      L+ V    F P  C T 
Sbjct: 2171 QGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATT 2230

Query: 572  --IPPLLFYEGCVFDRCH------------MTDLDVV---CSSLELYAALCASHDICIDW 614
               P L       F  CH            + D   V   C +L +Y A+C    +CI+W
Sbjct: 2231 DCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAMCHKFHVCIEW 2290

Query: 615  RGRTGHMCPFTCPADKVYQPC--GPSNPSYCYGNDSASLGAL-PE-AGPITEGCFCPEGM 670
              R    CPF C +D  YQ C      P  C       LG L PE    + EGC C EG 
Sbjct: 2291 --RRSDYCPFLCSSDSTYQACVTACEPPKTC---QDGILGPLDPEHCQVLGEGCVCSEGT 2345

Query: 671  TLFSTSAQVCVPTGCPRCLGPHGEPVKVGHTVGMDCQEC---TCEAATWTLTCRPKLC-- 725
             L    + +C+P     C    G P  +G T       C    C+A   T+      C  
Sbjct: 2346 ILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPD-TIVPVDLGCPS 2404

Query: 726  PLPPACPLPGFVPVPAAPQAGQCCPQYSCACNTSRCP-KPVGCPEGARAIPTYQEGACCP 784
            P P +C   G V +   P    CC    C CN + C      C  G R +  +QE +CCP
Sbjct: 2405 PRPESCLRFGEVAL-LLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCP 2463

Query: 785  VQNCSWTVCSINGTLYQPGAVVSSSLCETCRCELPGGPPSDAFVVSC-ETQICNTHCPVG 843
              +C                      C+   CE          V SC + QI  T     
Sbjct: 2464 SYSCE---------------------CDPDLCEA-------ELVPSCRQDQILIT----- 2490

Query: 844  FEYQEQSGQCCGTCVQVACVTNTSKSPAHLFYPGETWSDAGNH----CVTHQCEKHQDGL 899
                 + G  C T    AC       P      GE  +   N     C  +QC       
Sbjct: 2491 ----GRLGDSCCTSYFCACGDCPDSIPE--CQEGEALTVHRNTTELCCPLYQC------- 2537

Query: 900  VVVTTKKACPPLSCSLDEARM---SKDGCCRF------CPPPPPPYQNQSTCAVYHRSLI 950
              V     CP + C L  A +   S D CC +      C   P P      C ++ +S +
Sbjct: 2538 --VCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVP-----RCHLWEKSQL 2590

Query: 951  IQQ--------QGCSSSEPVRLAYC----RGNCGDSSSMYSLEGNTVEHRCQC 991
             ++         GC+  E V+   C     G      ++  L  + V H  +C
Sbjct: 2591 DEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHTSRC 2643



 Score = 82.8 bits (203), Expect = 2e-15
 Identities = 96/378 (25%), Positives = 137/378 (36%), Gaps = 62/378 (16%)

Query: 394 VCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVLVDNYFCGAEDGLSCPRSI 453
           +C  WG  H  TFDG YY      +Y LV +  P    F + V N         +C R++
Sbjct: 78  ICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAV 137

Query: 454 ILEY-HQDRVVLTRKPVHGVMTNEI-----------IFNNKVV--SPGFRKNGIVVSRIG 499
            L +  +  + L ++  HG M  ++           +    +V     F       S + 
Sbjct: 138 SLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAVY 197

Query: 500 VKMYATIPEL----------------GVQVMFSGLIFSVEVPFSKFANNTEGQCXXXXXX 543
           +KM    PEL                   V  SG +    V   +F ++ + Q       
Sbjct: 198 IKMS---PELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVV---EFVHSWQEQAPNQPPG 251

Query: 544 XTT---PPAPCL---PSPI------CQLILSKVFEPCHTVIPPLLFYEGCVFDRCH-MTD 590
            TT   P  PCL   P  +      C+ +L   F+ CH  + PL F   C  D C  M D
Sbjct: 252 PTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGD 311

Query: 591 LDVVCSSLELYAALCASHDICID-WRGRTGHMCPFTCPADK-VYQPCGPSNPSYCYGNDS 648
           +   C +L  YA  CA     +  WR +    C   C      Y  C    P+ C+   S
Sbjct: 312 VATWCRALAEYARACAQAGRPLQGWRTQL-RQCTVHCKEKAFTYNECIACCPASCHPRAS 370

Query: 649 ASLGALPEAGPITEGCFCPEGMTLFSTSAQVCVPTGCPRCLGPHGEPVKVGHTVGMDCQE 708
                +       +GC+CP G+ +F     V  P  CP     HG     G  V  DC  
Sbjct: 371 ----CVDSEIACVDGCYCPNGL-IFEDGGCV-APAECP--CEFHGTLYPPGSVVKEDCNT 422

Query: 709 CTCEAATWTLTCRPKLCP 726
           CTC +  W   C   +CP
Sbjct: 423 CTCTSGKW--ECSTAVCP 438



 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 28/73 (38%), Positives = 41/73 (56%), Gaps = 5/73 (6%)

Query: 557  CQLILSKVFEPCHTVIPPLLFYEGCVFDRCHMT---DLDVVCSSLELYAALCASHDICID 613
            C ++LS+VFE CH V+    FY  C+ D C  +   D +  C+S+  YA  C  H + +D
Sbjct: 1100 CSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVD 1159

Query: 614  WRGRTGHMCPFTC 626
            W  RT  +CP+ C
Sbjct: 1160 W--RTPRLCPYDC 1170



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 29/95 (30%), Positives = 38/95 (40%), Gaps = 16/95 (16%)

Query: 748 CCPQYSCACNTSRCPKPVGCPEGARAIPTYQEGACCPVQNCSWTVCSINGTLYQPGAVVS 807
           C P+ SC  +   C     CP G      +++G C     C    C  +GTLY PG+VV 
Sbjct: 365 CHPRASCVDSEIACVDGCYCPNGL----IFEDGGCVAPAECP---CEFHGTLYPPGSVVK 417

Query: 808 SSLCETCRCELPGGPPSDAFVVSCETQICNTHCPV 842
              C TC C         +    C T +C   C V
Sbjct: 418 ED-CNTCTC--------TSGKWECSTAVCPAECSV 443



 Score = 44.3 bits (103), Expect = 6e-04
 Identities = 25/78 (32%), Positives = 37/78 (47%), Gaps = 3/78 (3%)

Query: 386 CHHYQCQCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVLVDNYFCGAED 445
           C  + C   C+ +GD HY TFDG  + F+  C   LV+    V   F V+V+N  C    
Sbjct: 904 CTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDV--SFSVIVENVNC-YSS 960

Query: 446 GLSCPRSIILEYHQDRVV 463
           G+ C + I +      +V
Sbjct: 961 GMICRKFISINVGNSLIV 978



 Score = 33.9 bits (76), Expect = 0.84
 Identities = 25/102 (24%), Positives = 37/102 (36%), Gaps = 9/102 (8%)

Query: 626 CPADKVYQPCGPSNPSYCYGNDSASLGAL-----PEAGPITEGCFCPEGMTLFSTSAQVC 680
           CPA +V+  C   +       +      L        GP   GC CP+G+     +    
Sbjct: 811 CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDAC--F 868

Query: 681 VPTGCPRCLGPHGEPVKVGHTVGMDCQECTCEAATWTLTCRP 722
           +P  CP C    G+    G  V   C  C C+  ++  T  P
Sbjct: 869 LPEECP-CTW-KGKEYFPGDQVMSPCHTCVCQRGSFQCTLHP 908


>gi|239755543 PREDICTED: otogelin isoform 2 [Homo sapiens]
          Length = 2924

 Score =  165 bits (417), Expect = 2e-40
 Identities = 156/644 (24%), Positives = 235/644 (36%), Gaps = 187/644 (29%)

Query: 545  TTPPAPCLPSPICQLILSKVFEPCHTVIPPLLFYEGCVFDRCHMTDLDVVCSSLELYAAL 604
            TT  +PCL     +++ ++ F  CH  +PP  F E  + D  ++      C +L +Y A+
Sbjct: 2301 TTDCSPCL-----RMVSNRTFSACHRFVPPESFCELWIRDTKYVQQ---PCVALTVYVAM 2352

Query: 605  CASHDICIDWRGRTGHMCPFTCPADKVYQPC---------------GPSNPSY------- 642
            C    +CI+WR      CPF C +D  YQ C               GP +P +       
Sbjct: 2353 CHKFHVCIEWR--RSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEG 2410

Query: 643  CYGNDSASLG------ALPEAG------------------------------------PI 660
            C  ++   L        +PEA                                     P+
Sbjct: 2411 CVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPV 2470

Query: 661  TEGCFCP--EGMTLFSTSAQVCVPTGCPRCLGPH-----------GEPVKVGHTVGMDCQ 707
              GC  P  E    F   A + +PT  P CLG                 + GH +    Q
Sbjct: 2471 DLGCPSPRPESCLRFGEVA-LLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQ 2529

Query: 708  ECTCEAATWTLTCRPKLCP--LPPAC------------------------PLPGFVPVPA 741
            E +C   +++  C P LC   L P+C                          P  +P   
Sbjct: 2530 EDSC-CPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQ 2588

Query: 742  APQA--------GQCCPQYSCACNTSRCPKPVGCPEGARAIPTYQEGACCPVQNCS---- 789
              +A          CCP Y C C   RCP+ V C  G   +  +    CCP ++C     
Sbjct: 2589 EGEALTVHRNTTELCCPLYQCVCENFRCPQ-VQCGLGTALVEVWSPDRCCPYKSCECDCD 2647

Query: 790  ---------W--------------TVC--------------SINGTLYQPGAVV----SS 808
                     W               VC              S    + QPG  V    + 
Sbjct: 2648 TIPVPRCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSAD 2707

Query: 809  SLCETCRCELPGGPPSDAFVVSCETQICNTHCPVGFEYQEQS--GQCCGTCVQVACVTNT 866
             +C T RC     P ++ + ++  + +C+ HC    EY+       CCG+C  V+C+   
Sbjct: 2708 GVCHTSRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTF 2767

Query: 867  SKSPAHLFYPGETWSDAGNHCVTHQCEKHQDGLVVVTTKKACPPLS---CSLDEARM--S 921
                  LF PG +W      C  H C     G V+V +  +CPPL+   C+     +  S
Sbjct: 2768 PNGTTSLFLPGASWI---ADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPS 2824

Query: 922  KDGCCRFCPPPPPPYQNQSTCAVYHRSLIIQQQGCSSSEPVRLAYCRGNCGDSSSMYSLE 981
             +GCCR C       ++  +C      + I++  C SS PV L  C G C  S+S+Y+  
Sbjct: 2825 LEGCCRTCK------EDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRC-PSASIYNYN 2877

Query: 982  GNTVEHRCQCCQELRTSLRNVTLHC-TDGSSRAFSYTEVEECGC 1024
             NT    C+CC+E+    R+V L C T+ +   ++  E  +C C
Sbjct: 2878 INTYARFCKCCREVGLQRRSVQLFCATNATWVPYTVQEPTDCAC 2921



 Score =  108 bits (269), Expect = 3e-23
 Identities = 121/490 (24%), Positives = 178/490 (36%), Gaps = 81/490 (16%)

Query: 386 CHHYQCQCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVLVDNYFCGAED 445
           C    C   CS  GD H+ TFDG  YTF   C Y+L +      G F V + N  CG   
Sbjct: 504 CSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSS--GTFTVTLQNAPCGLNQ 561

Query: 446 GLSCPRSIILEYHQD---RVVLTRKPVHGVMTNEIIFNNKVVSPGFRKNGIVVSRIGVKM 502
             +C +S+ +  HQD   +V LT+        + ++F+   + P +  +   + R+    
Sbjct: 562 DGACVQSVSVILHQDPRRQVTLTQAG------DVLLFDQYKIIPPYTDDAFEIRRLSSVF 615

Query: 503 YATIPELGVQVMFS--GLIFSVEVPFSKFANNTEGQCXXXXXXX------------TTPP 548
                 +GV+V++   GL   ++V   ++  +T G C                   +TP 
Sbjct: 616 LRVRTNVGVRVLYDREGLRLYLQVD-QRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQ 674

Query: 549 ---------APCLP----SPI----------------CQLILSKVFEPCHTVIPPLLFYE 579
                    + C P    SP+                C ++  ++F PC   + P+ ++E
Sbjct: 675 LFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFE 734

Query: 580 GCVFDRCHMTDLDVVCSSLELYAALCASHDICIDWRGRTGHMCPFTCPADKVYQPCGPSN 639
            C  D C       +C++L  YA LC  H + +D+R R    C  +C A K Y PC    
Sbjct: 735 QCRRDACRCGQ-PCLCATLAHYAHLCRRHGLPVDFRARL-PACALSCEASKEYSPCVAPC 792

Query: 640 PSYCYGNDSASLGALPEAG-------PITEGCFCPEGMTLFSTSAQVCVPTGCPRCLGPH 692
              C   D AS  A    G          EGC CP   T   T A +CVP     C    
Sbjct: 793 GRTC--QDLASPEACGVDGGDDLSRDECVEGCACPPD-TYLDTQADLCVPRNQCSC-HFQ 848

Query: 693 GEPVKVGHTVGMDCQECTCEAATWTLTCR--PKLCPLPPACPLPGFVPVPAAPQAGQCCP 750
           G     G +       C C+    +   R     CP          +         + C 
Sbjct: 849 GVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCE 908

Query: 751 QYSCACNTSR---CPKPVGCPEGARAIPTYQEGACCPVQNCSWTVCSINGTLYQPGAVVS 807
           Q     + S    C     CP+G          AC   + C    C+  G  Y PG  V 
Sbjct: 909 QQLLNLSVSARGPCLSGCACPQGL----LRHGDACFLPEECP---CTWKGKEYFPGDQVM 961

Query: 808 SSLCETCRCE 817
           S  C TC C+
Sbjct: 962 SP-CHTCVCQ 970



 Score =  105 bits (263), Expect = 2e-22
 Identities = 187/773 (24%), Positives = 267/773 (34%), Gaps = 160/773 (20%)

Query: 304  TLPPAPATSPSISTSEPVTELGCPNAVPPRKKGETWATP----NCSEATC-EGNNVISLR 358
            T  P+  ++P++S  E + E     A        T   P    +C    C EG  +   +
Sbjct: 2018 TTEPSGRSAPALSIVEGLAEA---LATTTEANTSTTCVPIAEQDCVRHICLEGQLIRVNQ 2074

Query: 359  PRTCPR-VEKPTCANGYPAVKVADQDGCCHHYQCQCVCSGWGDPHYITFDGTYYTFLDNC 417
             + CP+    P C     AV+V   D CC  ++C C CS + D  ++TFDG++       
Sbjct: 2075 SQHCPQGAAPPRCGILGLAVRVGG-DRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEA 2133

Query: 418  TYVLVQQIVPVYGHFRVLVDNYFCGAEDGLSCPRSIILEYHQDRVVLTRKPVHGVMTNEI 477
             Y+L Q    +     V V +        L+ P   ++  +   +       H V  +  
Sbjct: 2134 IYILSQSPDEM---LTVHVLDCKSANLGHLNWPPFCLVMLNMTHL------AHQVTIDR- 2183

Query: 478  IFNNKV------VSPGFRKNGIVVSRIG-VKMYATIPELGVQVMFSGLIFSVEVPFSKFA 530
             FN KV      V P   + G  +   G + M  T  ++ +Q + S  +  VE   +  A
Sbjct: 2184 -FNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKA 2242

Query: 531  --NNTEGQCXXXXXXXTT-----------PPAPCLPSPICQLILSKV----FEP--CHTV 571
              +   G C        T            PAP L S      L+ V    F P  C T 
Sbjct: 2243 QGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATT 2302

Query: 572  --IPPLLFYEGCVFDRCH------------MTDLDVV---CSSLELYAALCASHDICIDW 614
               P L       F  CH            + D   V   C +L +Y A+C    +CI+W
Sbjct: 2303 DCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAMCHKFHVCIEW 2362

Query: 615  RGRTGHMCPFTCPADKVYQPC--GPSNPSYCYGNDSASLGAL-PE-AGPITEGCFCPEGM 670
              R    CPF C +D  YQ C      P  C       LG L PE    + EGC C EG 
Sbjct: 2363 --RRSDYCPFLCSSDSTYQACVTACEPPKTC---QDGILGPLDPEHCQVLGEGCVCSEGT 2417

Query: 671  TLFSTSAQVCVPTGCPRCLGPHGEPVKVGHTVGMDCQEC---TCEAATWTLTCRPKLC-- 725
             L    + +C+P     C    G P  +G T       C    C+A   T+      C  
Sbjct: 2418 ILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPD-TIVPVDLGCPS 2476

Query: 726  PLPPACPLPGFVPVPAAPQAGQCCPQYSCACNTSRCP-KPVGCPEGARAIPTYQEGACCP 784
            P P +C   G V +   P    CC    C CN + C      C  G R +  +QE +CCP
Sbjct: 2477 PRPESCLRFGEVAL-LLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCP 2535

Query: 785  VQNCSWTVCSINGTLYQPGAVVSSSLCETCRCELPGGPPSDAFVVSC-ETQICNTHCPVG 843
              +C                      C+   CE          V SC + QI  T     
Sbjct: 2536 SYSCE---------------------CDPDLCEA-------ELVPSCRQDQILIT----- 2562

Query: 844  FEYQEQSGQCCGTCVQVACVTNTSKSPAHLFYPGETWSDAGNH----CVTHQCEKHQDGL 899
                 + G  C T    AC       P      GE  +   N     C  +QC       
Sbjct: 2563 ----GRLGDSCCTSYFCACGDCPDSIPE--CQEGEALTVHRNTTELCCPLYQC------- 2609

Query: 900  VVVTTKKACPPLSCSLDEARM---SKDGCCRF------CPPPPPPYQNQSTCAVYHRSLI 950
              V     CP + C L  A +   S D CC +      C   P P      C ++ +S +
Sbjct: 2610 --VCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVP-----RCHLWEKSQL 2662

Query: 951  IQQ--------QGCSSSEPVRLAYC----RGNCGDSSSMYSLEGNTVEHRCQC 991
             ++         GC+  E V+   C     G      ++  L  + V H  +C
Sbjct: 2663 DEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHTSRC 2715



 Score = 82.8 bits (203), Expect = 2e-15
 Identities = 96/378 (25%), Positives = 137/378 (36%), Gaps = 62/378 (16%)

Query: 394 VCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVLVDNYFCGAEDGLSCPRSI 453
           +C  WG  H  TFDG YY      +Y LV +  P    F + V N         +C R++
Sbjct: 150 ICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAV 209

Query: 454 ILEY-HQDRVVLTRKPVHGVMTNEI-----------IFNNKVV--SPGFRKNGIVVSRIG 499
            L +  +  + L ++  HG M  ++           +    +V     F       S + 
Sbjct: 210 SLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAVY 269

Query: 500 VKMYATIPEL----------------GVQVMFSGLIFSVEVPFSKFANNTEGQCXXXXXX 543
           +KM    PEL                   V  SG +    V   +F ++ + Q       
Sbjct: 270 IKMS---PELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVV---EFVHSWQEQAPNQPPG 323

Query: 544 XTT---PPAPCL---PSPI------CQLILSKVFEPCHTVIPPLLFYEGCVFDRCH-MTD 590
            TT   P  PCL   P  +      C+ +L   F+ CH  + PL F   C  D C  M D
Sbjct: 324 PTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGD 383

Query: 591 LDVVCSSLELYAALCASHDICID-WRGRTGHMCPFTCPADK-VYQPCGPSNPSYCYGNDS 648
           +   C +L  YA  CA     +  WR +    C   C      Y  C    P+ C+   S
Sbjct: 384 VATWCRALAEYARACAQAGRPLQGWRTQL-RQCTVHCKEKAFTYNECIACCPASCHPRAS 442

Query: 649 ASLGALPEAGPITEGCFCPEGMTLFSTSAQVCVPTGCPRCLGPHGEPVKVGHTVGMDCQE 708
                +       +GC+CP G+ +F     V  P  CP     HG     G  V  DC  
Sbjct: 443 ----CVDSEIACVDGCYCPNGL-IFEDGGCV-APAECP--CEFHGTLYPPGSVVKEDCNT 494

Query: 709 CTCEAATWTLTCRPKLCP 726
           CTC +  W   C   +CP
Sbjct: 495 CTCTSGKW--ECSTAVCP 510



 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 28/73 (38%), Positives = 41/73 (56%), Gaps = 5/73 (6%)

Query: 557  CQLILSKVFEPCHTVIPPLLFYEGCVFDRCHMT---DLDVVCSSLELYAALCASHDICID 613
            C ++LS+VFE CH V+    FY  C+ D C  +   D +  C+S+  YA  C  H + +D
Sbjct: 1172 CSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVD 1231

Query: 614  WRGRTGHMCPFTC 626
            W  RT  +CP+ C
Sbjct: 1232 W--RTPRLCPYDC 1242



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 29/95 (30%), Positives = 38/95 (40%), Gaps = 16/95 (16%)

Query: 748 CCPQYSCACNTSRCPKPVGCPEGARAIPTYQEGACCPVQNCSWTVCSINGTLYQPGAVVS 807
           C P+ SC  +   C     CP G      +++G C     C    C  +GTLY PG+VV 
Sbjct: 437 CHPRASCVDSEIACVDGCYCPNGL----IFEDGGCVAPAECP---CEFHGTLYPPGSVVK 489

Query: 808 SSLCETCRCELPGGPPSDAFVVSCETQICNTHCPV 842
              C TC C         +    C T +C   C V
Sbjct: 490 ED-CNTCTC--------TSGKWECSTAVCPAECSV 515



 Score = 44.3 bits (103), Expect = 6e-04
 Identities = 25/78 (32%), Positives = 37/78 (47%), Gaps = 3/78 (3%)

Query: 386  CHHYQCQCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVLVDNYFCGAED 445
            C  + C   C+ +GD HY TFDG  + F+  C   LV+    V   F V+V+N  C    
Sbjct: 976  CTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDV--SFSVIVENVNC-YSS 1032

Query: 446  GLSCPRSIILEYHQDRVV 463
            G+ C + I +      +V
Sbjct: 1033 GMICRKFISINVGNSLIV 1050



 Score = 33.9 bits (76), Expect = 0.84
 Identities = 25/102 (24%), Positives = 37/102 (36%), Gaps = 9/102 (8%)

Query: 626 CPADKVYQPCGPSNPSYCYGNDSASLGAL-----PEAGPITEGCFCPEGMTLFSTSAQVC 680
           CPA +V+  C   +       +      L        GP   GC CP+G+     +    
Sbjct: 883 CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDAC--F 940

Query: 681 VPTGCPRCLGPHGEPVKVGHTVGMDCQECTCEAATWTLTCRP 722
           +P  CP C    G+    G  V   C  C C+  ++  T  P
Sbjct: 941 LPEECP-CTW-KGKEYFPGDQVMSPCHTCVCQRGSFQCTLHP 980


>gi|239749989 PREDICTED: otogelin isoform 2 [Homo sapiens]
          Length = 2852

 Score =  165 bits (417), Expect = 2e-40
 Identities = 156/644 (24%), Positives = 235/644 (36%), Gaps = 187/644 (29%)

Query: 545  TTPPAPCLPSPICQLILSKVFEPCHTVIPPLLFYEGCVFDRCHMTDLDVVCSSLELYAAL 604
            TT  +PCL     +++ ++ F  CH  +PP  F E  + D  ++      C +L +Y A+
Sbjct: 2229 TTDCSPCL-----RMVSNRTFSACHRFVPPESFCELWIRDTKYVQQ---PCVALTVYVAM 2280

Query: 605  CASHDICIDWRGRTGHMCPFTCPADKVYQPC---------------GPSNPSY------- 642
            C    +CI+WR      CPF C +D  YQ C               GP +P +       
Sbjct: 2281 CHKFHVCIEWR--RSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEG 2338

Query: 643  CYGNDSASLG------ALPEAG------------------------------------PI 660
            C  ++   L        +PEA                                     P+
Sbjct: 2339 CVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPV 2398

Query: 661  TEGCFCP--EGMTLFSTSAQVCVPTGCPRCLGPH-----------GEPVKVGHTVGMDCQ 707
              GC  P  E    F   A + +PT  P CLG                 + GH +    Q
Sbjct: 2399 DLGCPSPRPESCLRFGEVA-LLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQ 2457

Query: 708  ECTCEAATWTLTCRPKLCP--LPPAC------------------------PLPGFVPVPA 741
            E +C   +++  C P LC   L P+C                          P  +P   
Sbjct: 2458 EDSC-CPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQ 2516

Query: 742  APQA--------GQCCPQYSCACNTSRCPKPVGCPEGARAIPTYQEGACCPVQNCS---- 789
              +A          CCP Y C C   RCP+ V C  G   +  +    CCP ++C     
Sbjct: 2517 EGEALTVHRNTTELCCPLYQCVCENFRCPQ-VQCGLGTALVEVWSPDRCCPYKSCECDCD 2575

Query: 790  ---------W--------------TVC--------------SINGTLYQPGAVV----SS 808
                     W               VC              S    + QPG  V    + 
Sbjct: 2576 TIPVPRCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSAD 2635

Query: 809  SLCETCRCELPGGPPSDAFVVSCETQICNTHCPVGFEYQEQS--GQCCGTCVQVACVTNT 866
             +C T RC     P ++ + ++  + +C+ HC    EY+       CCG+C  V+C+   
Sbjct: 2636 GVCHTSRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTF 2695

Query: 867  SKSPAHLFYPGETWSDAGNHCVTHQCEKHQDGLVVVTTKKACPPLS---CSLDEARM--S 921
                  LF PG +W      C  H C     G V+V +  +CPPL+   C+     +  S
Sbjct: 2696 PNGTTSLFLPGASWI---ADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPS 2752

Query: 922  KDGCCRFCPPPPPPYQNQSTCAVYHRSLIIQQQGCSSSEPVRLAYCRGNCGDSSSMYSLE 981
             +GCCR C       ++  +C      + I++  C SS PV L  C G C  S+S+Y+  
Sbjct: 2753 LEGCCRTCK------EDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRC-PSASIYNYN 2805

Query: 982  GNTVEHRCQCCQELRTSLRNVTLHC-TDGSSRAFSYTEVEECGC 1024
             NT    C+CC+E+    R+V L C T+ +   ++  E  +C C
Sbjct: 2806 INTYARFCKCCREVGLQRRSVQLFCATNATWVPYTVQEPTDCAC 2849



 Score =  108 bits (269), Expect = 3e-23
 Identities = 121/490 (24%), Positives = 178/490 (36%), Gaps = 81/490 (16%)

Query: 386 CHHYQCQCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVLVDNYFCGAED 445
           C    C   CS  GD H+ TFDG  YTF   C Y+L +      G F V + N  CG   
Sbjct: 432 CSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSS--GTFTVTLQNAPCGLNQ 489

Query: 446 GLSCPRSIILEYHQD---RVVLTRKPVHGVMTNEIIFNNKVVSPGFRKNGIVVSRIGVKM 502
             +C +S+ +  HQD   +V LT+        + ++F+   + P +  +   + R+    
Sbjct: 490 DGACVQSVSVILHQDPRRQVTLTQAG------DVLLFDQYKIIPPYTDDAFEIRRLSSVF 543

Query: 503 YATIPELGVQVMFS--GLIFSVEVPFSKFANNTEGQCXXXXXXX------------TTPP 548
                 +GV+V++   GL   ++V   ++  +T G C                   +TP 
Sbjct: 544 LRVRTNVGVRVLYDREGLRLYLQVD-QRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQ 602

Query: 549 ---------APCLP----SPI----------------CQLILSKVFEPCHTVIPPLLFYE 579
                    + C P    SP+                C ++  ++F PC   + P+ ++E
Sbjct: 603 LFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFE 662

Query: 580 GCVFDRCHMTDLDVVCSSLELYAALCASHDICIDWRGRTGHMCPFTCPADKVYQPCGPSN 639
            C  D C       +C++L  YA LC  H + +D+R R    C  +C A K Y PC    
Sbjct: 663 QCRRDACRCGQ-PCLCATLAHYAHLCRRHGLPVDFRARL-PACALSCEASKEYSPCVAPC 720

Query: 640 PSYCYGNDSASLGALPEAG-------PITEGCFCPEGMTLFSTSAQVCVPTGCPRCLGPH 692
              C   D AS  A    G          EGC CP   T   T A +CVP     C    
Sbjct: 721 GRTC--QDLASPEACGVDGGDDLSRDECVEGCACPPD-TYLDTQADLCVPRNQCSC-HFQ 776

Query: 693 GEPVKVGHTVGMDCQECTCEAATWTLTCR--PKLCPLPPACPLPGFVPVPAAPQAGQCCP 750
           G     G +       C C+    +   R     CP          +         + C 
Sbjct: 777 GVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCE 836

Query: 751 QYSCACNTSR---CPKPVGCPEGARAIPTYQEGACCPVQNCSWTVCSINGTLYQPGAVVS 807
           Q     + S    C     CP+G          AC   + C    C+  G  Y PG  V 
Sbjct: 837 QQLLNLSVSARGPCLSGCACPQGL----LRHGDACFLPEECP---CTWKGKEYFPGDQVM 889

Query: 808 SSLCETCRCE 817
           S  C TC C+
Sbjct: 890 SP-CHTCVCQ 898



 Score =  105 bits (263), Expect = 2e-22
 Identities = 187/773 (24%), Positives = 267/773 (34%), Gaps = 160/773 (20%)

Query: 304  TLPPAPATSPSISTSEPVTELGCPNAVPPRKKGETWATP----NCSEATC-EGNNVISLR 358
            T  P+  ++P++S  E + E     A        T   P    +C    C EG  +   +
Sbjct: 1946 TTEPSGRSAPALSIVEGLAEA---LATTTEANTSTTCVPIAEQDCVRHICLEGQLIRVNQ 2002

Query: 359  PRTCPR-VEKPTCANGYPAVKVADQDGCCHHYQCQCVCSGWGDPHYITFDGTYYTFLDNC 417
             + CP+    P C     AV+V   D CC  ++C C CS + D  ++TFDG++       
Sbjct: 2003 SQHCPQGAAPPRCGILGLAVRVGG-DRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEA 2061

Query: 418  TYVLVQQIVPVYGHFRVLVDNYFCGAEDGLSCPRSIILEYHQDRVVLTRKPVHGVMTNEI 477
             Y+L Q    +     V V +        L+ P   ++  +   +       H V  +  
Sbjct: 2062 IYILSQSPDEM---LTVHVLDCKSANLGHLNWPPFCLVMLNMTHL------AHQVTIDR- 2111

Query: 478  IFNNKV------VSPGFRKNGIVVSRIG-VKMYATIPELGVQVMFSGLIFSVEVPFSKFA 530
             FN KV      V P   + G  +   G + M  T  ++ +Q + S  +  VE   +  A
Sbjct: 2112 -FNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKA 2170

Query: 531  --NNTEGQCXXXXXXXTT-----------PPAPCLPSPICQLILSKV----FEP--CHTV 571
              +   G C        T            PAP L S      L+ V    F P  C T 
Sbjct: 2171 QGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATT 2230

Query: 572  --IPPLLFYEGCVFDRCH------------MTDLDVV---CSSLELYAALCASHDICIDW 614
               P L       F  CH            + D   V   C +L +Y A+C    +CI+W
Sbjct: 2231 DCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAMCHKFHVCIEW 2290

Query: 615  RGRTGHMCPFTCPADKVYQPC--GPSNPSYCYGNDSASLGAL-PE-AGPITEGCFCPEGM 670
              R    CPF C +D  YQ C      P  C       LG L PE    + EGC C EG 
Sbjct: 2291 --RRSDYCPFLCSSDSTYQACVTACEPPKTC---QDGILGPLDPEHCQVLGEGCVCSEGT 2345

Query: 671  TLFSTSAQVCVPTGCPRCLGPHGEPVKVGHTVGMDCQEC---TCEAATWTLTCRPKLC-- 725
             L    + +C+P     C    G P  +G T       C    C+A   T+      C  
Sbjct: 2346 ILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPD-TIVPVDLGCPS 2404

Query: 726  PLPPACPLPGFVPVPAAPQAGQCCPQYSCACNTSRCP-KPVGCPEGARAIPTYQEGACCP 784
            P P +C   G V +   P    CC    C CN + C      C  G R +  +QE +CCP
Sbjct: 2405 PRPESCLRFGEVAL-LLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCP 2463

Query: 785  VQNCSWTVCSINGTLYQPGAVVSSSLCETCRCELPGGPPSDAFVVSC-ETQICNTHCPVG 843
              +C                      C+   CE          V SC + QI  T     
Sbjct: 2464 SYSCE---------------------CDPDLCEA-------ELVPSCRQDQILIT----- 2490

Query: 844  FEYQEQSGQCCGTCVQVACVTNTSKSPAHLFYPGETWSDAGNH----CVTHQCEKHQDGL 899
                 + G  C T    AC       P      GE  +   N     C  +QC       
Sbjct: 2491 ----GRLGDSCCTSYFCACGDCPDSIPE--CQEGEALTVHRNTTELCCPLYQC------- 2537

Query: 900  VVVTTKKACPPLSCSLDEARM---SKDGCCRF------CPPPPPPYQNQSTCAVYHRSLI 950
              V     CP + C L  A +   S D CC +      C   P P      C ++ +S +
Sbjct: 2538 --VCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVP-----RCHLWEKSQL 2590

Query: 951  IQQ--------QGCSSSEPVRLAYC----RGNCGDSSSMYSLEGNTVEHRCQC 991
             ++         GC+  E V+   C     G      ++  L  + V H  +C
Sbjct: 2591 DEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHTSRC 2643



 Score = 82.8 bits (203), Expect = 2e-15
 Identities = 96/378 (25%), Positives = 137/378 (36%), Gaps = 62/378 (16%)

Query: 394 VCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVLVDNYFCGAEDGLSCPRSI 453
           +C  WG  H  TFDG YY      +Y LV +  P    F + V N         +C R++
Sbjct: 78  ICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAV 137

Query: 454 ILEY-HQDRVVLTRKPVHGVMTNEI-----------IFNNKVV--SPGFRKNGIVVSRIG 499
            L +  +  + L ++  HG M  ++           +    +V     F       S + 
Sbjct: 138 SLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAVY 197

Query: 500 VKMYATIPEL----------------GVQVMFSGLIFSVEVPFSKFANNTEGQCXXXXXX 543
           +KM    PEL                   V  SG +    V   +F ++ + Q       
Sbjct: 198 IKMS---PELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVV---EFVHSWQEQAPNQPPG 251

Query: 544 XTT---PPAPCL---PSPI------CQLILSKVFEPCHTVIPPLLFYEGCVFDRCH-MTD 590
            TT   P  PCL   P  +      C+ +L   F+ CH  + PL F   C  D C  M D
Sbjct: 252 PTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGD 311

Query: 591 LDVVCSSLELYAALCASHDICID-WRGRTGHMCPFTCPADK-VYQPCGPSNPSYCYGNDS 648
           +   C +L  YA  CA     +  WR +    C   C      Y  C    P+ C+   S
Sbjct: 312 VATWCRALAEYARACAQAGRPLQGWRTQL-RQCTVHCKEKAFTYNECIACCPASCHPRAS 370

Query: 649 ASLGALPEAGPITEGCFCPEGMTLFSTSAQVCVPTGCPRCLGPHGEPVKVGHTVGMDCQE 708
                +       +GC+CP G+ +F     V  P  CP     HG     G  V  DC  
Sbjct: 371 ----CVDSEIACVDGCYCPNGL-IFEDGGCV-APAECP--CEFHGTLYPPGSVVKEDCNT 422

Query: 709 CTCEAATWTLTCRPKLCP 726
           CTC +  W   C   +CP
Sbjct: 423 CTCTSGKW--ECSTAVCP 438



 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 28/73 (38%), Positives = 41/73 (56%), Gaps = 5/73 (6%)

Query: 557  CQLILSKVFEPCHTVIPPLLFYEGCVFDRCHMT---DLDVVCSSLELYAALCASHDICID 613
            C ++LS+VFE CH V+    FY  C+ D C  +   D +  C+S+  YA  C  H + +D
Sbjct: 1100 CSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVD 1159

Query: 614  WRGRTGHMCPFTC 626
            W  RT  +CP+ C
Sbjct: 1160 W--RTPRLCPYDC 1170



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 29/95 (30%), Positives = 38/95 (40%), Gaps = 16/95 (16%)

Query: 748 CCPQYSCACNTSRCPKPVGCPEGARAIPTYQEGACCPVQNCSWTVCSINGTLYQPGAVVS 807
           C P+ SC  +   C     CP G      +++G C     C    C  +GTLY PG+VV 
Sbjct: 365 CHPRASCVDSEIACVDGCYCPNGL----IFEDGGCVAPAECP---CEFHGTLYPPGSVVK 417

Query: 808 SSLCETCRCELPGGPPSDAFVVSCETQICNTHCPV 842
              C TC C         +    C T +C   C V
Sbjct: 418 ED-CNTCTC--------TSGKWECSTAVCPAECSV 443



 Score = 44.3 bits (103), Expect = 6e-04
 Identities = 25/78 (32%), Positives = 37/78 (47%), Gaps = 3/78 (3%)

Query: 386 CHHYQCQCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVLVDNYFCGAED 445
           C  + C   C+ +GD HY TFDG  + F+  C   LV+    V   F V+V+N  C    
Sbjct: 904 CTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDV--SFSVIVENVNC-YSS 960

Query: 446 GLSCPRSIILEYHQDRVV 463
           G+ C + I +      +V
Sbjct: 961 GMICRKFISINVGNSLIV 978



 Score = 33.9 bits (76), Expect = 0.84
 Identities = 25/102 (24%), Positives = 37/102 (36%), Gaps = 9/102 (8%)

Query: 626 CPADKVYQPCGPSNPSYCYGNDSASLGAL-----PEAGPITEGCFCPEGMTLFSTSAQVC 680
           CPA +V+  C   +       +      L        GP   GC CP+G+     +    
Sbjct: 811 CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDAC--F 868

Query: 681 VPTGCPRCLGPHGEPVKVGHTVGMDCQECTCEAATWTLTCRP 722
           +P  CP C    G+    G  V   C  C C+  ++  T  P
Sbjct: 869 LPEECP-CTW-KGKEYFPGDQVMSPCHTCVCQRGSFQCTLHP 908


>gi|239749987 PREDICTED: otogelin isoform 1 [Homo sapiens]
          Length = 2924

 Score =  165 bits (417), Expect = 2e-40
 Identities = 156/644 (24%), Positives = 235/644 (36%), Gaps = 187/644 (29%)

Query: 545  TTPPAPCLPSPICQLILSKVFEPCHTVIPPLLFYEGCVFDRCHMTDLDVVCSSLELYAAL 604
            TT  +PCL     +++ ++ F  CH  +PP  F E  + D  ++      C +L +Y A+
Sbjct: 2301 TTDCSPCL-----RMVSNRTFSACHRFVPPESFCELWIRDTKYVQQ---PCVALTVYVAM 2352

Query: 605  CASHDICIDWRGRTGHMCPFTCPADKVYQPC---------------GPSNPSY------- 642
            C    +CI+WR      CPF C +D  YQ C               GP +P +       
Sbjct: 2353 CHKFHVCIEWR--RSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEG 2410

Query: 643  CYGNDSASLG------ALPEAG------------------------------------PI 660
            C  ++   L        +PEA                                     P+
Sbjct: 2411 CVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPV 2470

Query: 661  TEGCFCP--EGMTLFSTSAQVCVPTGCPRCLGPH-----------GEPVKVGHTVGMDCQ 707
              GC  P  E    F   A + +PT  P CLG                 + GH +    Q
Sbjct: 2471 DLGCPSPRPESCLRFGEVA-LLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQ 2529

Query: 708  ECTCEAATWTLTCRPKLCP--LPPAC------------------------PLPGFVPVPA 741
            E +C   +++  C P LC   L P+C                          P  +P   
Sbjct: 2530 EDSC-CPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQ 2588

Query: 742  APQA--------GQCCPQYSCACNTSRCPKPVGCPEGARAIPTYQEGACCPVQNCS---- 789
              +A          CCP Y C C   RCP+ V C  G   +  +    CCP ++C     
Sbjct: 2589 EGEALTVHRNTTELCCPLYQCVCENFRCPQ-VQCGLGTALVEVWSPDRCCPYKSCECDCD 2647

Query: 790  ---------W--------------TVC--------------SINGTLYQPGAVV----SS 808
                     W               VC              S    + QPG  V    + 
Sbjct: 2648 TIPVPRCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSAD 2707

Query: 809  SLCETCRCELPGGPPSDAFVVSCETQICNTHCPVGFEYQEQS--GQCCGTCVQVACVTNT 866
             +C T RC     P ++ + ++  + +C+ HC    EY+       CCG+C  V+C+   
Sbjct: 2708 GVCHTSRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTF 2767

Query: 867  SKSPAHLFYPGETWSDAGNHCVTHQCEKHQDGLVVVTTKKACPPLS---CSLDEARM--S 921
                  LF PG +W      C  H C     G V+V +  +CPPL+   C+     +  S
Sbjct: 2768 PNGTTSLFLPGASWI---ADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPS 2824

Query: 922  KDGCCRFCPPPPPPYQNQSTCAVYHRSLIIQQQGCSSSEPVRLAYCRGNCGDSSSMYSLE 981
             +GCCR C       ++  +C      + I++  C SS PV L  C G C  S+S+Y+  
Sbjct: 2825 LEGCCRTCK------EDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRC-PSASIYNYN 2877

Query: 982  GNTVEHRCQCCQELRTSLRNVTLHC-TDGSSRAFSYTEVEECGC 1024
             NT    C+CC+E+    R+V L C T+ +   ++  E  +C C
Sbjct: 2878 INTYARFCKCCREVGLQRRSVQLFCATNATWVPYTVQEPTDCAC 2921



 Score =  108 bits (269), Expect = 3e-23
 Identities = 121/490 (24%), Positives = 178/490 (36%), Gaps = 81/490 (16%)

Query: 386 CHHYQCQCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVLVDNYFCGAED 445
           C    C   CS  GD H+ TFDG  YTF   C Y+L +      G F V + N  CG   
Sbjct: 504 CSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSS--GTFTVTLQNAPCGLNQ 561

Query: 446 GLSCPRSIILEYHQD---RVVLTRKPVHGVMTNEIIFNNKVVSPGFRKNGIVVSRIGVKM 502
             +C +S+ +  HQD   +V LT+        + ++F+   + P +  +   + R+    
Sbjct: 562 DGACVQSVSVILHQDPRRQVTLTQAG------DVLLFDQYKIIPPYTDDAFEIRRLSSVF 615

Query: 503 YATIPELGVQVMFS--GLIFSVEVPFSKFANNTEGQCXXXXXXX------------TTPP 548
                 +GV+V++   GL   ++V   ++  +T G C                   +TP 
Sbjct: 616 LRVRTNVGVRVLYDREGLRLYLQVD-QRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQ 674

Query: 549 ---------APCLP----SPI----------------CQLILSKVFEPCHTVIPPLLFYE 579
                    + C P    SP+                C ++  ++F PC   + P+ ++E
Sbjct: 675 LFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFE 734

Query: 580 GCVFDRCHMTDLDVVCSSLELYAALCASHDICIDWRGRTGHMCPFTCPADKVYQPCGPSN 639
            C  D C       +C++L  YA LC  H + +D+R R    C  +C A K Y PC    
Sbjct: 735 QCRRDACRCGQ-PCLCATLAHYAHLCRRHGLPVDFRARL-PACALSCEASKEYSPCVAPC 792

Query: 640 PSYCYGNDSASLGALPEAG-------PITEGCFCPEGMTLFSTSAQVCVPTGCPRCLGPH 692
              C   D AS  A    G          EGC CP   T   T A +CVP     C    
Sbjct: 793 GRTC--QDLASPEACGVDGGDDLSRDECVEGCACPPD-TYLDTQADLCVPRNQCSC-HFQ 848

Query: 693 GEPVKVGHTVGMDCQECTCEAATWTLTCR--PKLCPLPPACPLPGFVPVPAAPQAGQCCP 750
           G     G +       C C+    +   R     CP          +         + C 
Sbjct: 849 GVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCE 908

Query: 751 QYSCACNTSR---CPKPVGCPEGARAIPTYQEGACCPVQNCSWTVCSINGTLYQPGAVVS 807
           Q     + S    C     CP+G          AC   + C    C+  G  Y PG  V 
Sbjct: 909 QQLLNLSVSARGPCLSGCACPQGL----LRHGDACFLPEECP---CTWKGKEYFPGDQVM 961

Query: 808 SSLCETCRCE 817
           S  C TC C+
Sbjct: 962 SP-CHTCVCQ 970



 Score =  105 bits (263), Expect = 2e-22
 Identities = 187/773 (24%), Positives = 267/773 (34%), Gaps = 160/773 (20%)

Query: 304  TLPPAPATSPSISTSEPVTELGCPNAVPPRKKGETWATP----NCSEATC-EGNNVISLR 358
            T  P+  ++P++S  E + E     A        T   P    +C    C EG  +   +
Sbjct: 2018 TTEPSGRSAPALSIVEGLAEA---LATTTEANTSTTCVPIAEQDCVRHICLEGQLIRVNQ 2074

Query: 359  PRTCPR-VEKPTCANGYPAVKVADQDGCCHHYQCQCVCSGWGDPHYITFDGTYYTFLDNC 417
             + CP+    P C     AV+V   D CC  ++C C CS + D  ++TFDG++       
Sbjct: 2075 SQHCPQGAAPPRCGILGLAVRVGG-DRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEA 2133

Query: 418  TYVLVQQIVPVYGHFRVLVDNYFCGAEDGLSCPRSIILEYHQDRVVLTRKPVHGVMTNEI 477
             Y+L Q    +     V V +        L+ P   ++  +   +       H V  +  
Sbjct: 2134 IYILSQSPDEM---LTVHVLDCKSANLGHLNWPPFCLVMLNMTHL------AHQVTIDR- 2183

Query: 478  IFNNKV------VSPGFRKNGIVVSRIG-VKMYATIPELGVQVMFSGLIFSVEVPFSKFA 530
             FN KV      V P   + G  +   G + M  T  ++ +Q + S  +  VE   +  A
Sbjct: 2184 -FNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKA 2242

Query: 531  --NNTEGQCXXXXXXXTT-----------PPAPCLPSPICQLILSKV----FEP--CHTV 571
              +   G C        T            PAP L S      L+ V    F P  C T 
Sbjct: 2243 QGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATT 2302

Query: 572  --IPPLLFYEGCVFDRCH------------MTDLDVV---CSSLELYAALCASHDICIDW 614
               P L       F  CH            + D   V   C +L +Y A+C    +CI+W
Sbjct: 2303 DCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAMCHKFHVCIEW 2362

Query: 615  RGRTGHMCPFTCPADKVYQPC--GPSNPSYCYGNDSASLGAL-PE-AGPITEGCFCPEGM 670
              R    CPF C +D  YQ C      P  C       LG L PE    + EGC C EG 
Sbjct: 2363 --RRSDYCPFLCSSDSTYQACVTACEPPKTC---QDGILGPLDPEHCQVLGEGCVCSEGT 2417

Query: 671  TLFSTSAQVCVPTGCPRCLGPHGEPVKVGHTVGMDCQEC---TCEAATWTLTCRPKLC-- 725
             L    + +C+P     C    G P  +G T       C    C+A   T+      C  
Sbjct: 2418 ILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPD-TIVPVDLGCPS 2476

Query: 726  PLPPACPLPGFVPVPAAPQAGQCCPQYSCACNTSRCP-KPVGCPEGARAIPTYQEGACCP 784
            P P +C   G V +   P    CC    C CN + C      C  G R +  +QE +CCP
Sbjct: 2477 PRPESCLRFGEVAL-LLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCP 2535

Query: 785  VQNCSWTVCSINGTLYQPGAVVSSSLCETCRCELPGGPPSDAFVVSC-ETQICNTHCPVG 843
              +C                      C+   CE          V SC + QI  T     
Sbjct: 2536 SYSCE---------------------CDPDLCEA-------ELVPSCRQDQILIT----- 2562

Query: 844  FEYQEQSGQCCGTCVQVACVTNTSKSPAHLFYPGETWSDAGNH----CVTHQCEKHQDGL 899
                 + G  C T    AC       P      GE  +   N     C  +QC       
Sbjct: 2563 ----GRLGDSCCTSYFCACGDCPDSIPE--CQEGEALTVHRNTTELCCPLYQC------- 2609

Query: 900  VVVTTKKACPPLSCSLDEARM---SKDGCCRF------CPPPPPPYQNQSTCAVYHRSLI 950
              V     CP + C L  A +   S D CC +      C   P P      C ++ +S +
Sbjct: 2610 --VCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVP-----RCHLWEKSQL 2662

Query: 951  IQQ--------QGCSSSEPVRLAYC----RGNCGDSSSMYSLEGNTVEHRCQC 991
             ++         GC+  E V+   C     G      ++  L  + V H  +C
Sbjct: 2663 DEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHTSRC 2715



 Score = 82.8 bits (203), Expect = 2e-15
 Identities = 96/378 (25%), Positives = 137/378 (36%), Gaps = 62/378 (16%)

Query: 394 VCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVLVDNYFCGAEDGLSCPRSI 453
           +C  WG  H  TFDG YY      +Y LV +  P    F + V N         +C R++
Sbjct: 150 ICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAV 209

Query: 454 ILEY-HQDRVVLTRKPVHGVMTNEI-----------IFNNKVV--SPGFRKNGIVVSRIG 499
            L +  +  + L ++  HG M  ++           +    +V     F       S + 
Sbjct: 210 SLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAVY 269

Query: 500 VKMYATIPEL----------------GVQVMFSGLIFSVEVPFSKFANNTEGQCXXXXXX 543
           +KM    PEL                   V  SG +    V   +F ++ + Q       
Sbjct: 270 IKMS---PELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVV---EFVHSWQEQAPNQPPG 323

Query: 544 XTT---PPAPCL---PSPI------CQLILSKVFEPCHTVIPPLLFYEGCVFDRCH-MTD 590
            TT   P  PCL   P  +      C+ +L   F+ CH  + PL F   C  D C  M D
Sbjct: 324 PTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGD 383

Query: 591 LDVVCSSLELYAALCASHDICID-WRGRTGHMCPFTCPADK-VYQPCGPSNPSYCYGNDS 648
           +   C +L  YA  CA     +  WR +    C   C      Y  C    P+ C+   S
Sbjct: 384 VATWCRALAEYARACAQAGRPLQGWRTQL-RQCTVHCKEKAFTYNECIACCPASCHPRAS 442

Query: 649 ASLGALPEAGPITEGCFCPEGMTLFSTSAQVCVPTGCPRCLGPHGEPVKVGHTVGMDCQE 708
                +       +GC+CP G+ +F     V  P  CP     HG     G  V  DC  
Sbjct: 443 ----CVDSEIACVDGCYCPNGL-IFEDGGCV-APAECP--CEFHGTLYPPGSVVKEDCNT 494

Query: 709 CTCEAATWTLTCRPKLCP 726
           CTC +  W   C   +CP
Sbjct: 495 CTCTSGKW--ECSTAVCP 510



 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 28/73 (38%), Positives = 41/73 (56%), Gaps = 5/73 (6%)

Query: 557  CQLILSKVFEPCHTVIPPLLFYEGCVFDRCHMT---DLDVVCSSLELYAALCASHDICID 613
            C ++LS+VFE CH V+    FY  C+ D C  +   D +  C+S+  YA  C  H + +D
Sbjct: 1172 CSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVD 1231

Query: 614  WRGRTGHMCPFTC 626
            W  RT  +CP+ C
Sbjct: 1232 W--RTPRLCPYDC 1242



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 29/95 (30%), Positives = 38/95 (40%), Gaps = 16/95 (16%)

Query: 748 CCPQYSCACNTSRCPKPVGCPEGARAIPTYQEGACCPVQNCSWTVCSINGTLYQPGAVVS 807
           C P+ SC  +   C     CP G      +++G C     C    C  +GTLY PG+VV 
Sbjct: 437 CHPRASCVDSEIACVDGCYCPNGL----IFEDGGCVAPAECP---CEFHGTLYPPGSVVK 489

Query: 808 SSLCETCRCELPGGPPSDAFVVSCETQICNTHCPV 842
              C TC C         +    C T +C   C V
Sbjct: 490 ED-CNTCTC--------TSGKWECSTAVCPAECSV 515



 Score = 44.3 bits (103), Expect = 6e-04
 Identities = 25/78 (32%), Positives = 37/78 (47%), Gaps = 3/78 (3%)

Query: 386  CHHYQCQCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVLVDNYFCGAED 445
            C  + C   C+ +GD HY TFDG  + F+  C   LV+    V   F V+V+N  C    
Sbjct: 976  CTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDV--SFSVIVENVNC-YSS 1032

Query: 446  GLSCPRSIILEYHQDRVV 463
            G+ C + I +      +V
Sbjct: 1033 GMICRKFISINVGNSLIV 1050



 Score = 33.9 bits (76), Expect = 0.84
 Identities = 25/102 (24%), Positives = 37/102 (36%), Gaps = 9/102 (8%)

Query: 626 CPADKVYQPCGPSNPSYCYGNDSASLGAL-----PEAGPITEGCFCPEGMTLFSTSAQVC 680
           CPA +V+  C   +       +      L        GP   GC CP+G+     +    
Sbjct: 883 CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDAC--F 940

Query: 681 VPTGCPRCLGPHGEPVKVGHTVGMDCQECTCEAATWTLTCRP 722
           +P  CP C    G+    G  V   C  C C+  ++  T  P
Sbjct: 941 LPEECP-CTW-KGKEYFPGDQVMSPCHTCVCQRGSFQCTLHP 980


>gi|239744300 PREDICTED: otogelin isoform 2 [Homo sapiens]
          Length = 2852

 Score =  165 bits (417), Expect = 2e-40
 Identities = 156/644 (24%), Positives = 235/644 (36%), Gaps = 187/644 (29%)

Query: 545  TTPPAPCLPSPICQLILSKVFEPCHTVIPPLLFYEGCVFDRCHMTDLDVVCSSLELYAAL 604
            TT  +PCL     +++ ++ F  CH  +PP  F E  + D  ++      C +L +Y A+
Sbjct: 2229 TTDCSPCL-----RMVSNRTFSACHRFVPPESFCELWIRDTKYVQQ---PCVALTVYVAM 2280

Query: 605  CASHDICIDWRGRTGHMCPFTCPADKVYQPC---------------GPSNPSY------- 642
            C    +CI+WR      CPF C +D  YQ C               GP +P +       
Sbjct: 2281 CHKFHVCIEWR--RSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEG 2338

Query: 643  CYGNDSASLG------ALPEAG------------------------------------PI 660
            C  ++   L        +PEA                                     P+
Sbjct: 2339 CVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPV 2398

Query: 661  TEGCFCP--EGMTLFSTSAQVCVPTGCPRCLGPH-----------GEPVKVGHTVGMDCQ 707
              GC  P  E    F   A + +PT  P CLG                 + GH +    Q
Sbjct: 2399 DLGCPSPRPESCLRFGEVA-LLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQ 2457

Query: 708  ECTCEAATWTLTCRPKLCP--LPPAC------------------------PLPGFVPVPA 741
            E +C   +++  C P LC   L P+C                          P  +P   
Sbjct: 2458 EDSC-CPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQ 2516

Query: 742  APQA--------GQCCPQYSCACNTSRCPKPVGCPEGARAIPTYQEGACCPVQNCS---- 789
              +A          CCP Y C C   RCP+ V C  G   +  +    CCP ++C     
Sbjct: 2517 EGEALTVHRNTTELCCPLYQCVCENFRCPQ-VQCGLGTALVEVWSPDRCCPYKSCECDCD 2575

Query: 790  ---------W--------------TVC--------------SINGTLYQPGAVV----SS 808
                     W               VC              S    + QPG  V    + 
Sbjct: 2576 TIPVPRCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSAD 2635

Query: 809  SLCETCRCELPGGPPSDAFVVSCETQICNTHCPVGFEYQEQS--GQCCGTCVQVACVTNT 866
             +C T RC     P ++ + ++  + +C+ HC    EY+       CCG+C  V+C+   
Sbjct: 2636 GVCHTSRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTF 2695

Query: 867  SKSPAHLFYPGETWSDAGNHCVTHQCEKHQDGLVVVTTKKACPPLS---CSLDEARM--S 921
                  LF PG +W      C  H C     G V+V +  +CPPL+   C+     +  S
Sbjct: 2696 PNGTTSLFLPGASWI---ADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPS 2752

Query: 922  KDGCCRFCPPPPPPYQNQSTCAVYHRSLIIQQQGCSSSEPVRLAYCRGNCGDSSSMYSLE 981
             +GCCR C       ++  +C      + I++  C SS PV L  C G C  S+S+Y+  
Sbjct: 2753 LEGCCRTCK------EDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRC-PSASIYNYN 2805

Query: 982  GNTVEHRCQCCQELRTSLRNVTLHC-TDGSSRAFSYTEVEECGC 1024
             NT    C+CC+E+    R+V L C T+ +   ++  E  +C C
Sbjct: 2806 INTYARFCKCCREVGLQRRSVQLFCATNATWVPYTVQEPTDCAC 2849



 Score =  108 bits (269), Expect = 3e-23
 Identities = 121/490 (24%), Positives = 178/490 (36%), Gaps = 81/490 (16%)

Query: 386 CHHYQCQCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVLVDNYFCGAED 445
           C    C   CS  GD H+ TFDG  YTF   C Y+L +      G F V + N  CG   
Sbjct: 432 CSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSS--GTFTVTLQNAPCGLNQ 489

Query: 446 GLSCPRSIILEYHQD---RVVLTRKPVHGVMTNEIIFNNKVVSPGFRKNGIVVSRIGVKM 502
             +C +S+ +  HQD   +V LT+        + ++F+   + P +  +   + R+    
Sbjct: 490 DGACVQSVSVILHQDPRRQVTLTQAG------DVLLFDQYKIIPPYTDDAFEIRRLSSVF 543

Query: 503 YATIPELGVQVMFS--GLIFSVEVPFSKFANNTEGQCXXXXXXX------------TTPP 548
                 +GV+V++   GL   ++V   ++  +T G C                   +TP 
Sbjct: 544 LRVRTNVGVRVLYDREGLRLYLQVD-QRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQ 602

Query: 549 ---------APCLP----SPI----------------CQLILSKVFEPCHTVIPPLLFYE 579
                    + C P    SP+                C ++  ++F PC   + P+ ++E
Sbjct: 603 LFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFE 662

Query: 580 GCVFDRCHMTDLDVVCSSLELYAALCASHDICIDWRGRTGHMCPFTCPADKVYQPCGPSN 639
            C  D C       +C++L  YA LC  H + +D+R R    C  +C A K Y PC    
Sbjct: 663 QCRRDACRCGQ-PCLCATLAHYAHLCRRHGLPVDFRARL-PACALSCEASKEYSPCVAPC 720

Query: 640 PSYCYGNDSASLGALPEAG-------PITEGCFCPEGMTLFSTSAQVCVPTGCPRCLGPH 692
              C   D AS  A    G          EGC CP   T   T A +CVP     C    
Sbjct: 721 GRTC--QDLASPEACGVDGGDDLSRDECVEGCACPPD-TYLDTQADLCVPRNQCSC-HFQ 776

Query: 693 GEPVKVGHTVGMDCQECTCEAATWTLTCR--PKLCPLPPACPLPGFVPVPAAPQAGQCCP 750
           G     G +       C C+    +   R     CP          +         + C 
Sbjct: 777 GVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCE 836

Query: 751 QYSCACNTSR---CPKPVGCPEGARAIPTYQEGACCPVQNCSWTVCSINGTLYQPGAVVS 807
           Q     + S    C     CP+G          AC   + C    C+  G  Y PG  V 
Sbjct: 837 QQLLNLSVSARGPCLSGCACPQGL----LRHGDACFLPEECP---CTWKGKEYFPGDQVM 889

Query: 808 SSLCETCRCE 817
           S  C TC C+
Sbjct: 890 SP-CHTCVCQ 898



 Score =  105 bits (263), Expect = 2e-22
 Identities = 187/773 (24%), Positives = 267/773 (34%), Gaps = 160/773 (20%)

Query: 304  TLPPAPATSPSISTSEPVTELGCPNAVPPRKKGETWATP----NCSEATC-EGNNVISLR 358
            T  P+  ++P++S  E + E     A        T   P    +C    C EG  +   +
Sbjct: 1946 TTEPSGRSAPALSIVEGLAEA---LATTTEANTSTTCVPIAEQDCVRHICLEGQLIRVNQ 2002

Query: 359  PRTCPR-VEKPTCANGYPAVKVADQDGCCHHYQCQCVCSGWGDPHYITFDGTYYTFLDNC 417
             + CP+    P C     AV+V   D CC  ++C C CS + D  ++TFDG++       
Sbjct: 2003 SQHCPQGAAPPRCGILGLAVRVGG-DRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEA 2061

Query: 418  TYVLVQQIVPVYGHFRVLVDNYFCGAEDGLSCPRSIILEYHQDRVVLTRKPVHGVMTNEI 477
             Y+L Q    +     V V +        L+ P   ++  +   +       H V  +  
Sbjct: 2062 IYILSQSPDEM---LTVHVLDCKSANLGHLNWPPFCLVMLNMTHL------AHQVTIDR- 2111

Query: 478  IFNNKV------VSPGFRKNGIVVSRIG-VKMYATIPELGVQVMFSGLIFSVEVPFSKFA 530
             FN KV      V P   + G  +   G + M  T  ++ +Q + S  +  VE   +  A
Sbjct: 2112 -FNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKA 2170

Query: 531  --NNTEGQCXXXXXXXTT-----------PPAPCLPSPICQLILSKV----FEP--CHTV 571
              +   G C        T            PAP L S      L+ V    F P  C T 
Sbjct: 2171 QGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATT 2230

Query: 572  --IPPLLFYEGCVFDRCH------------MTDLDVV---CSSLELYAALCASHDICIDW 614
               P L       F  CH            + D   V   C +L +Y A+C    +CI+W
Sbjct: 2231 DCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAMCHKFHVCIEW 2290

Query: 615  RGRTGHMCPFTCPADKVYQPC--GPSNPSYCYGNDSASLGAL-PE-AGPITEGCFCPEGM 670
              R    CPF C +D  YQ C      P  C       LG L PE    + EGC C EG 
Sbjct: 2291 --RRSDYCPFLCSSDSTYQACVTACEPPKTC---QDGILGPLDPEHCQVLGEGCVCSEGT 2345

Query: 671  TLFSTSAQVCVPTGCPRCLGPHGEPVKVGHTVGMDCQEC---TCEAATWTLTCRPKLC-- 725
             L    + +C+P     C    G P  +G T       C    C+A   T+      C  
Sbjct: 2346 ILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPD-TIVPVDLGCPS 2404

Query: 726  PLPPACPLPGFVPVPAAPQAGQCCPQYSCACNTSRCP-KPVGCPEGARAIPTYQEGACCP 784
            P P +C   G V +   P    CC    C CN + C      C  G R +  +QE +CCP
Sbjct: 2405 PRPESCLRFGEVAL-LLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCP 2463

Query: 785  VQNCSWTVCSINGTLYQPGAVVSSSLCETCRCELPGGPPSDAFVVSC-ETQICNTHCPVG 843
              +C                      C+   CE          V SC + QI  T     
Sbjct: 2464 SYSCE---------------------CDPDLCEA-------ELVPSCRQDQILIT----- 2490

Query: 844  FEYQEQSGQCCGTCVQVACVTNTSKSPAHLFYPGETWSDAGNH----CVTHQCEKHQDGL 899
                 + G  C T    AC       P      GE  +   N     C  +QC       
Sbjct: 2491 ----GRLGDSCCTSYFCACGDCPDSIPE--CQEGEALTVHRNTTELCCPLYQC------- 2537

Query: 900  VVVTTKKACPPLSCSLDEARM---SKDGCCRF------CPPPPPPYQNQSTCAVYHRSLI 950
              V     CP + C L  A +   S D CC +      C   P P      C ++ +S +
Sbjct: 2538 --VCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVP-----RCHLWEKSQL 2590

Query: 951  IQQ--------QGCSSSEPVRLAYC----RGNCGDSSSMYSLEGNTVEHRCQC 991
             ++         GC+  E V+   C     G      ++  L  + V H  +C
Sbjct: 2591 DEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHTSRC 2643



 Score = 82.8 bits (203), Expect = 2e-15
 Identities = 96/378 (25%), Positives = 137/378 (36%), Gaps = 62/378 (16%)

Query: 394 VCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVLVDNYFCGAEDGLSCPRSI 453
           +C  WG  H  TFDG YY      +Y LV +  P    F + V N         +C R++
Sbjct: 78  ICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAV 137

Query: 454 ILEY-HQDRVVLTRKPVHGVMTNEI-----------IFNNKVV--SPGFRKNGIVVSRIG 499
            L +  +  + L ++  HG M  ++           +    +V     F       S + 
Sbjct: 138 SLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAVY 197

Query: 500 VKMYATIPEL----------------GVQVMFSGLIFSVEVPFSKFANNTEGQCXXXXXX 543
           +KM    PEL                   V  SG +    V   +F ++ + Q       
Sbjct: 198 IKMS---PELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVV---EFVHSWQEQAPNQPPG 251

Query: 544 XTT---PPAPCL---PSPI------CQLILSKVFEPCHTVIPPLLFYEGCVFDRCH-MTD 590
            TT   P  PCL   P  +      C+ +L   F+ CH  + PL F   C  D C  M D
Sbjct: 252 PTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGD 311

Query: 591 LDVVCSSLELYAALCASHDICID-WRGRTGHMCPFTCPADK-VYQPCGPSNPSYCYGNDS 648
           +   C +L  YA  CA     +  WR +    C   C      Y  C    P+ C+   S
Sbjct: 312 VATWCRALAEYARACAQAGRPLQGWRTQL-RQCTVHCKEKAFTYNECIACCPASCHPRAS 370

Query: 649 ASLGALPEAGPITEGCFCPEGMTLFSTSAQVCVPTGCPRCLGPHGEPVKVGHTVGMDCQE 708
                +       +GC+CP G+ +F     V  P  CP     HG     G  V  DC  
Sbjct: 371 ----CVDSEIACVDGCYCPNGL-IFEDGGCV-APAECP--CEFHGTLYPPGSVVKEDCNT 422

Query: 709 CTCEAATWTLTCRPKLCP 726
           CTC +  W   C   +CP
Sbjct: 423 CTCTSGKW--ECSTAVCP 438



 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 28/73 (38%), Positives = 41/73 (56%), Gaps = 5/73 (6%)

Query: 557  CQLILSKVFEPCHTVIPPLLFYEGCVFDRCHMT---DLDVVCSSLELYAALCASHDICID 613
            C ++LS+VFE CH V+    FY  C+ D C  +   D +  C+S+  YA  C  H + +D
Sbjct: 1100 CSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVD 1159

Query: 614  WRGRTGHMCPFTC 626
            W  RT  +CP+ C
Sbjct: 1160 W--RTPRLCPYDC 1170



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 29/95 (30%), Positives = 38/95 (40%), Gaps = 16/95 (16%)

Query: 748 CCPQYSCACNTSRCPKPVGCPEGARAIPTYQEGACCPVQNCSWTVCSINGTLYQPGAVVS 807
           C P+ SC  +   C     CP G      +++G C     C    C  +GTLY PG+VV 
Sbjct: 365 CHPRASCVDSEIACVDGCYCPNGL----IFEDGGCVAPAECP---CEFHGTLYPPGSVVK 417

Query: 808 SSLCETCRCELPGGPPSDAFVVSCETQICNTHCPV 842
              C TC C         +    C T +C   C V
Sbjct: 418 ED-CNTCTC--------TSGKWECSTAVCPAECSV 443



 Score = 44.3 bits (103), Expect = 6e-04
 Identities = 25/78 (32%), Positives = 37/78 (47%), Gaps = 3/78 (3%)

Query: 386 CHHYQCQCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVLVDNYFCGAED 445
           C  + C   C+ +GD HY TFDG  + F+  C   LV+    V   F V+V+N  C    
Sbjct: 904 CTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDV--SFSVIVENVNC-YSS 960

Query: 446 GLSCPRSIILEYHQDRVV 463
           G+ C + I +      +V
Sbjct: 961 GMICRKFISINVGNSLIV 978



 Score = 33.9 bits (76), Expect = 0.84
 Identities = 25/102 (24%), Positives = 37/102 (36%), Gaps = 9/102 (8%)

Query: 626 CPADKVYQPCGPSNPSYCYGNDSASLGAL-----PEAGPITEGCFCPEGMTLFSTSAQVC 680
           CPA +V+  C   +       +      L        GP   GC CP+G+     +    
Sbjct: 811 CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDAC--F 868

Query: 681 VPTGCPRCLGPHGEPVKVGHTVGMDCQECTCEAATWTLTCRP 722
           +P  CP C    G+    G  V   C  C C+  ++  T  P
Sbjct: 869 LPEECP-CTW-KGKEYFPGDQVMSPCHTCVCQRGSFQCTLHP 908


>gi|239744298 PREDICTED: otogelin isoform 1 [Homo sapiens]
          Length = 2924

 Score =  165 bits (417), Expect = 2e-40
 Identities = 156/644 (24%), Positives = 235/644 (36%), Gaps = 187/644 (29%)

Query: 545  TTPPAPCLPSPICQLILSKVFEPCHTVIPPLLFYEGCVFDRCHMTDLDVVCSSLELYAAL 604
            TT  +PCL     +++ ++ F  CH  +PP  F E  + D  ++      C +L +Y A+
Sbjct: 2301 TTDCSPCL-----RMVSNRTFSACHRFVPPESFCELWIRDTKYVQQ---PCVALTVYVAM 2352

Query: 605  CASHDICIDWRGRTGHMCPFTCPADKVYQPC---------------GPSNPSY------- 642
            C    +CI+WR      CPF C +D  YQ C               GP +P +       
Sbjct: 2353 CHKFHVCIEWR--RSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEG 2410

Query: 643  CYGNDSASLG------ALPEAG------------------------------------PI 660
            C  ++   L        +PEA                                     P+
Sbjct: 2411 CVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPV 2470

Query: 661  TEGCFCP--EGMTLFSTSAQVCVPTGCPRCLGPH-----------GEPVKVGHTVGMDCQ 707
              GC  P  E    F   A + +PT  P CLG                 + GH +    Q
Sbjct: 2471 DLGCPSPRPESCLRFGEVA-LLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQ 2529

Query: 708  ECTCEAATWTLTCRPKLCP--LPPAC------------------------PLPGFVPVPA 741
            E +C   +++  C P LC   L P+C                          P  +P   
Sbjct: 2530 EDSC-CPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQ 2588

Query: 742  APQA--------GQCCPQYSCACNTSRCPKPVGCPEGARAIPTYQEGACCPVQNCS---- 789
              +A          CCP Y C C   RCP+ V C  G   +  +    CCP ++C     
Sbjct: 2589 EGEALTVHRNTTELCCPLYQCVCENFRCPQ-VQCGLGTALVEVWSPDRCCPYKSCECDCD 2647

Query: 790  ---------W--------------TVC--------------SINGTLYQPGAVV----SS 808
                     W               VC              S    + QPG  V    + 
Sbjct: 2648 TIPVPRCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSAD 2707

Query: 809  SLCETCRCELPGGPPSDAFVVSCETQICNTHCPVGFEYQEQS--GQCCGTCVQVACVTNT 866
             +C T RC     P ++ + ++  + +C+ HC    EY+       CCG+C  V+C+   
Sbjct: 2708 GVCHTSRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTF 2767

Query: 867  SKSPAHLFYPGETWSDAGNHCVTHQCEKHQDGLVVVTTKKACPPLS---CSLDEARM--S 921
                  LF PG +W      C  H C     G V+V +  +CPPL+   C+     +  S
Sbjct: 2768 PNGTTSLFLPGASWI---ADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPS 2824

Query: 922  KDGCCRFCPPPPPPYQNQSTCAVYHRSLIIQQQGCSSSEPVRLAYCRGNCGDSSSMYSLE 981
             +GCCR C       ++  +C      + I++  C SS PV L  C G C  S+S+Y+  
Sbjct: 2825 LEGCCRTCK------EDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRC-PSASIYNYN 2877

Query: 982  GNTVEHRCQCCQELRTSLRNVTLHC-TDGSSRAFSYTEVEECGC 1024
             NT    C+CC+E+    R+V L C T+ +   ++  E  +C C
Sbjct: 2878 INTYARFCKCCREVGLQRRSVQLFCATNATWVPYTVQEPTDCAC 2921



 Score =  108 bits (269), Expect = 3e-23
 Identities = 121/490 (24%), Positives = 178/490 (36%), Gaps = 81/490 (16%)

Query: 386 CHHYQCQCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVLVDNYFCGAED 445
           C    C   CS  GD H+ TFDG  YTF   C Y+L +      G F V + N  CG   
Sbjct: 504 CSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSS--GTFTVTLQNAPCGLNQ 561

Query: 446 GLSCPRSIILEYHQD---RVVLTRKPVHGVMTNEIIFNNKVVSPGFRKNGIVVSRIGVKM 502
             +C +S+ +  HQD   +V LT+        + ++F+   + P +  +   + R+    
Sbjct: 562 DGACVQSVSVILHQDPRRQVTLTQAG------DVLLFDQYKIIPPYTDDAFEIRRLSSVF 615

Query: 503 YATIPELGVQVMFS--GLIFSVEVPFSKFANNTEGQCXXXXXXX------------TTPP 548
                 +GV+V++   GL   ++V   ++  +T G C                   +TP 
Sbjct: 616 LRVRTNVGVRVLYDREGLRLYLQVD-QRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQ 674

Query: 549 ---------APCLP----SPI----------------CQLILSKVFEPCHTVIPPLLFYE 579
                    + C P    SP+                C ++  ++F PC   + P+ ++E
Sbjct: 675 LFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFE 734

Query: 580 GCVFDRCHMTDLDVVCSSLELYAALCASHDICIDWRGRTGHMCPFTCPADKVYQPCGPSN 639
            C  D C       +C++L  YA LC  H + +D+R R    C  +C A K Y PC    
Sbjct: 735 QCRRDACRCGQ-PCLCATLAHYAHLCRRHGLPVDFRARL-PACALSCEASKEYSPCVAPC 792

Query: 640 PSYCYGNDSASLGALPEAG-------PITEGCFCPEGMTLFSTSAQVCVPTGCPRCLGPH 692
              C   D AS  A    G          EGC CP   T   T A +CVP     C    
Sbjct: 793 GRTC--QDLASPEACGVDGGDDLSRDECVEGCACPPD-TYLDTQADLCVPRNQCSC-HFQ 848

Query: 693 GEPVKVGHTVGMDCQECTCEAATWTLTCR--PKLCPLPPACPLPGFVPVPAAPQAGQCCP 750
           G     G +       C C+    +   R     CP          +         + C 
Sbjct: 849 GVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCE 908

Query: 751 QYSCACNTSR---CPKPVGCPEGARAIPTYQEGACCPVQNCSWTVCSINGTLYQPGAVVS 807
           Q     + S    C     CP+G          AC   + C    C+  G  Y PG  V 
Sbjct: 909 QQLLNLSVSARGPCLSGCACPQGL----LRHGDACFLPEECP---CTWKGKEYFPGDQVM 961

Query: 808 SSLCETCRCE 817
           S  C TC C+
Sbjct: 962 SP-CHTCVCQ 970



 Score =  105 bits (263), Expect = 2e-22
 Identities = 187/773 (24%), Positives = 267/773 (34%), Gaps = 160/773 (20%)

Query: 304  TLPPAPATSPSISTSEPVTELGCPNAVPPRKKGETWATP----NCSEATC-EGNNVISLR 358
            T  P+  ++P++S  E + E     A        T   P    +C    C EG  +   +
Sbjct: 2018 TTEPSGRSAPALSIVEGLAEA---LATTTEANTSTTCVPIAEQDCVRHICLEGQLIRVNQ 2074

Query: 359  PRTCPR-VEKPTCANGYPAVKVADQDGCCHHYQCQCVCSGWGDPHYITFDGTYYTFLDNC 417
             + CP+    P C     AV+V   D CC  ++C C CS + D  ++TFDG++       
Sbjct: 2075 SQHCPQGAAPPRCGILGLAVRVGG-DRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEA 2133

Query: 418  TYVLVQQIVPVYGHFRVLVDNYFCGAEDGLSCPRSIILEYHQDRVVLTRKPVHGVMTNEI 477
             Y+L Q    +     V V +        L+ P   ++  +   +       H V  +  
Sbjct: 2134 IYILSQSPDEM---LTVHVLDCKSANLGHLNWPPFCLVMLNMTHL------AHQVTIDR- 2183

Query: 478  IFNNKV------VSPGFRKNGIVVSRIG-VKMYATIPELGVQVMFSGLIFSVEVPFSKFA 530
             FN KV      V P   + G  +   G + M  T  ++ +Q + S  +  VE   +  A
Sbjct: 2184 -FNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKA 2242

Query: 531  --NNTEGQCXXXXXXXTT-----------PPAPCLPSPICQLILSKV----FEP--CHTV 571
              +   G C        T            PAP L S      L+ V    F P  C T 
Sbjct: 2243 QGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATT 2302

Query: 572  --IPPLLFYEGCVFDRCH------------MTDLDVV---CSSLELYAALCASHDICIDW 614
               P L       F  CH            + D   V   C +L +Y A+C    +CI+W
Sbjct: 2303 DCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAMCHKFHVCIEW 2362

Query: 615  RGRTGHMCPFTCPADKVYQPC--GPSNPSYCYGNDSASLGAL-PE-AGPITEGCFCPEGM 670
              R    CPF C +D  YQ C      P  C       LG L PE    + EGC C EG 
Sbjct: 2363 --RRSDYCPFLCSSDSTYQACVTACEPPKTC---QDGILGPLDPEHCQVLGEGCVCSEGT 2417

Query: 671  TLFSTSAQVCVPTGCPRCLGPHGEPVKVGHTVGMDCQEC---TCEAATWTLTCRPKLC-- 725
             L    + +C+P     C    G P  +G T       C    C+A   T+      C  
Sbjct: 2418 ILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPD-TIVPVDLGCPS 2476

Query: 726  PLPPACPLPGFVPVPAAPQAGQCCPQYSCACNTSRCP-KPVGCPEGARAIPTYQEGACCP 784
            P P +C   G V +   P    CC    C CN + C      C  G R +  +QE +CCP
Sbjct: 2477 PRPESCLRFGEVAL-LLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCP 2535

Query: 785  VQNCSWTVCSINGTLYQPGAVVSSSLCETCRCELPGGPPSDAFVVSC-ETQICNTHCPVG 843
              +C                      C+   CE          V SC + QI  T     
Sbjct: 2536 SYSCE---------------------CDPDLCEA-------ELVPSCRQDQILIT----- 2562

Query: 844  FEYQEQSGQCCGTCVQVACVTNTSKSPAHLFYPGETWSDAGNH----CVTHQCEKHQDGL 899
                 + G  C T    AC       P      GE  +   N     C  +QC       
Sbjct: 2563 ----GRLGDSCCTSYFCACGDCPDSIPE--CQEGEALTVHRNTTELCCPLYQC------- 2609

Query: 900  VVVTTKKACPPLSCSLDEARM---SKDGCCRF------CPPPPPPYQNQSTCAVYHRSLI 950
              V     CP + C L  A +   S D CC +      C   P P      C ++ +S +
Sbjct: 2610 --VCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVP-----RCHLWEKSQL 2662

Query: 951  IQQ--------QGCSSSEPVRLAYC----RGNCGDSSSMYSLEGNTVEHRCQC 991
             ++         GC+  E V+   C     G      ++  L  + V H  +C
Sbjct: 2663 DEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHTSRC 2715



 Score = 82.8 bits (203), Expect = 2e-15
 Identities = 96/378 (25%), Positives = 137/378 (36%), Gaps = 62/378 (16%)

Query: 394 VCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVLVDNYFCGAEDGLSCPRSI 453
           +C  WG  H  TFDG YY      +Y LV +  P    F + V N         +C R++
Sbjct: 150 ICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAV 209

Query: 454 ILEY-HQDRVVLTRKPVHGVMTNEI-----------IFNNKVV--SPGFRKNGIVVSRIG 499
            L +  +  + L ++  HG M  ++           +    +V     F       S + 
Sbjct: 210 SLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAVY 269

Query: 500 VKMYATIPEL----------------GVQVMFSGLIFSVEVPFSKFANNTEGQCXXXXXX 543
           +KM    PEL                   V  SG +    V   +F ++ + Q       
Sbjct: 270 IKMS---PELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVV---EFVHSWQEQAPNQPPG 323

Query: 544 XTT---PPAPCL---PSPI------CQLILSKVFEPCHTVIPPLLFYEGCVFDRCH-MTD 590
            TT   P  PCL   P  +      C+ +L   F+ CH  + PL F   C  D C  M D
Sbjct: 324 PTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGD 383

Query: 591 LDVVCSSLELYAALCASHDICID-WRGRTGHMCPFTCPADK-VYQPCGPSNPSYCYGNDS 648
           +   C +L  YA  CA     +  WR +    C   C      Y  C    P+ C+   S
Sbjct: 384 VATWCRALAEYARACAQAGRPLQGWRTQL-RQCTVHCKEKAFTYNECIACCPASCHPRAS 442

Query: 649 ASLGALPEAGPITEGCFCPEGMTLFSTSAQVCVPTGCPRCLGPHGEPVKVGHTVGMDCQE 708
                +       +GC+CP G+ +F     V  P  CP     HG     G  V  DC  
Sbjct: 443 ----CVDSEIACVDGCYCPNGL-IFEDGGCV-APAECP--CEFHGTLYPPGSVVKEDCNT 494

Query: 709 CTCEAATWTLTCRPKLCP 726
           CTC +  W   C   +CP
Sbjct: 495 CTCTSGKW--ECSTAVCP 510



 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 28/73 (38%), Positives = 41/73 (56%), Gaps = 5/73 (6%)

Query: 557  CQLILSKVFEPCHTVIPPLLFYEGCVFDRCHMT---DLDVVCSSLELYAALCASHDICID 613
            C ++LS+VFE CH V+    FY  C+ D C  +   D +  C+S+  YA  C  H + +D
Sbjct: 1172 CSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVD 1231

Query: 614  WRGRTGHMCPFTC 626
            W  RT  +CP+ C
Sbjct: 1232 W--RTPRLCPYDC 1242



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 29/95 (30%), Positives = 38/95 (40%), Gaps = 16/95 (16%)

Query: 748 CCPQYSCACNTSRCPKPVGCPEGARAIPTYQEGACCPVQNCSWTVCSINGTLYQPGAVVS 807
           C P+ SC  +   C     CP G      +++G C     C    C  +GTLY PG+VV 
Sbjct: 437 CHPRASCVDSEIACVDGCYCPNGL----IFEDGGCVAPAECP---CEFHGTLYPPGSVVK 489

Query: 808 SSLCETCRCELPGGPPSDAFVVSCETQICNTHCPV 842
              C TC C         +    C T +C   C V
Sbjct: 490 ED-CNTCTC--------TSGKWECSTAVCPAECSV 515



 Score = 44.3 bits (103), Expect = 6e-04
 Identities = 25/78 (32%), Positives = 37/78 (47%), Gaps = 3/78 (3%)

Query: 386  CHHYQCQCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVLVDNYFCGAED 445
            C  + C   C+ +GD HY TFDG  + F+  C   LV+    V   F V+V+N  C    
Sbjct: 976  CTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDV--SFSVIVENVNC-YSS 1032

Query: 446  GLSCPRSIILEYHQDRVV 463
            G+ C + I +      +V
Sbjct: 1033 GMICRKFISINVGNSLIV 1050



 Score = 33.9 bits (76), Expect = 0.84
 Identities = 25/102 (24%), Positives = 37/102 (36%), Gaps = 9/102 (8%)

Query: 626 CPADKVYQPCGPSNPSYCYGNDSASLGAL-----PEAGPITEGCFCPEGMTLFSTSAQVC 680
           CPA +V+  C   +       +      L        GP   GC CP+G+     +    
Sbjct: 883 CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDAC--F 940

Query: 681 VPTGCPRCLGPHGEPVKVGHTVGMDCQECTCEAATWTLTCRP 722
           +P  CP C    G+    G  V   C  C C+  ++  T  P
Sbjct: 941 LPEECP-CTW-KGKEYFPGDQVMSPCHTCVCQRGSFQCTLHP 980


>gi|16554449 zonadhesin isoform 3 [Homo sapiens]
          Length = 2812

 Score =  129 bits (325), Expect = 1e-29
 Identities = 131/470 (27%), Positives = 179/470 (38%), Gaps = 88/470 (18%)

Query: 320  PVTELGCPNAVPPR-KKGETWATPNCSE-ATCEGNNVISLRPRTCPRVEKPTCANGYPAV 377
            P ++ GC +      K GE W  P C E   CE NN I  +P  C   E     +G    
Sbjct: 1475 PRSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIY-- 1532

Query: 378  KVADQDGCCHHYQCQCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVLVD 437
                  GC  H Q    C+  GDPHY+TFDG  + F+  CTYVL +   P +   +   D
Sbjct: 1533 ------GC--HAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTR---PCWSRSQ---D 1578

Query: 438  NYFCGAEDGLSCPRSIILEYHQDRVV------LTRKPVHG--VMTNEIIFNNKVVSPGFR 489
            +YF  +    +  R  ILE    + V      L+   + G  VM N     ++V  P + 
Sbjct: 1579 SYFVVSATNEN--RGGILEVSYIKAVHVTVFDLSISLLRGCKVMLN----GHRVALPVWL 1632

Query: 490  KNGIVVSRIGVKMYATIPELGVQVMFSGL-IFSVEVPFS----------KFANNT----- 533
              G V  R+   +       G+QV + G  +  V VP S           + NN+     
Sbjct: 1633 AQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNL 1692

Query: 534  ------EGQCXXXXXXXTTP-------------PAPCLPSPI-------CQLILSKV--F 565
                   G           P             P+ C  + +       C ++++    F
Sbjct: 1693 RPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGPF 1752

Query: 566  EPCHTVIPPLLFYEGCVFDRCHMT-DLDVVCSSLELYAALCASHDICIDWRGRTGHMCPF 624
              CH V+PP   +  CV  +C    D   +C SL+ YA+LCA       WR RT   CP 
Sbjct: 1753 SQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQAPAWRNRT--FCPM 1810

Query: 625  TCPADKVYQPCGPSNPSYCYGNDSASLGALPEAGPITEGCFCPEGMTLFSTSAQVCVPTG 684
             CP    Y PC    P  C   ++      P+A P  E C C +G  L  TS   CVP G
Sbjct: 1811 RCPPGSSYSPCSSPCPDTCSSINNPR--DCPKALPCAESCECQKGHILSGTS---CVPLG 1865

Query: 685  CPRCLGPHGEPVKVG---HTVGMDCQECTCEAATWTLTCRPKLCPLPPAC 731
               C  P G    VG   +T     + CTC      +TC    C     C
Sbjct: 1866 QCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHN-NITCFQSTCKPNQIC 1914



 Score = 99.8 bits (247), Expect = 1e-20
 Identities = 108/449 (24%), Positives = 156/449 (34%), Gaps = 81/449 (18%)

Query: 336  GETWATPNCSE-ATCEGNNVISLRPRTCPRVEKPTCANGYPAVKVADQDGCCHHYQCQCV 394
            G  W +PNC+E   C   + +  +   C         NG        Q GC H Y     
Sbjct: 1105 GAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNG--------QYGC-HPYAGTAT 1155

Query: 395  CSGWGDPHYITFDGTYYTFLDNCTYVLVQQI-VPVYGHFRVLVDNYFCGAEDGLSCPRSI 453
            C  +GDPHY+TFDG ++ F+  CTY+L Q         FRV   N   G ++G+SC   +
Sbjct: 1156 CLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQG-QEGVSCLSKV 1214

Query: 454  ILEYHQDRVVLTRKPVHGVMTNEIIFNNKVVSPGFRKNGIVVSRIGVKMYATIPELGVQV 513
             +   +  V L +          ++   +V  P     G+ +   G +      E G++V
Sbjct: 1215 YVTLPESTVTLLKG------RRTLVGGQQVTLPAIPSKGVFLGASG-RFVELQTEFGLRV 1267

Query: 514  MFSG---LIFSVEVPFS----KFANNTEGQCXXXXXXXTTPPA----------------- 549
             + G   L  +V   +S        N +G            PA                 
Sbjct: 1268 RWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDED 1327

Query: 550  ------PCLPSPICQLILSK----------------VFEPCHTVIPPLLFYEGCVFDRCH 587
                    + SP C   L                   FE C   +    F++ C+ D C 
Sbjct: 1328 QECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCG 1387

Query: 588  MTDLD-VVCSSLELYAALC--ASHDICIDWRGRTGHMCPFTCPADKVYQPCGPSNPSYCY 644
               L  ++C+ +      C  A H +   W  R  H CP  CP +  Y  C    P  C+
Sbjct: 1388 FQGLQHLLCTHMSTMTTTCQDAGHAV-KPW--REPHFCPMACPPNSKYSLCAKPCPDTCH 1444

Query: 645  GNDSASLGALPEAGPITEGCFCPEGMTLFSTSAQVCVPTGCPRCLGPHGEPVKVGHT-VG 703
               S        +    E C C  G  L   S   C+P     CL P G   KVG     
Sbjct: 1445 SGFSGMFC----SDRCVEACECNPGFVL---SGLECIPRSQCGCLHPAGSYFKVGERWYK 1497

Query: 704  MDCQE-CTCEAATWTLTCRPKLCPLPPAC 731
              C+E C CE+    + C+P  C     C
Sbjct: 1498 PGCKELCVCESNN-RIRCQPWRCRAQEFC 1525



 Score = 79.7 bits (195), Expect = 1e-14
 Identities = 127/526 (24%), Positives = 189/526 (35%), Gaps = 104/526 (19%)

Query: 283  YALCSQDC-QVVRGVDS--DCPSTTLPPAPATSP------SISTSEPVTELGCPN-AVPP 332
            Y+ CS  C      +++  DCP   LP A +         S ++  P+ + GC + A   
Sbjct: 1818 YSPCSSPCPDTCSSINNPRDCPKA-LPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSY 1876

Query: 333  RKKGETWATPN-CSE-ATCEGNNVISLRPRTCPRVEKPTCANGYPAVKVADQDGCCHHYQ 390
               GE W T N C+   TC  +N I+    TC   +     +G    + +          
Sbjct: 1877 HPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVG------- 1929

Query: 391  CQCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVLVDNYFCGAEDGLSCP 450
               VC   G+ HY++FDG+ ++  D CT VLV+   P        +       E G    
Sbjct: 1930 ---VCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAF 1986

Query: 451  R--SIILEYHQDRVVLTRKPVHGVMTNEIIFNNKVVS--PGFR-KNGIVVSRIGVKMYAT 505
            R   + ++ +  +V L +   H V+ N        +S  PG   K+  + S + +K    
Sbjct: 1987 RLHEVYIDIYDAQVTLQKG--HRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIK---- 2040

Query: 506  IPELGVQVMFSGL-IFSVEVPF--------------------------------SKFANN 532
               +GVQV F G  +  +E+P                                 S+F N+
Sbjct: 2041 ---IGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNS 2097

Query: 533  TEGQ-----CXXXXXXXTTPPAPCLPSPI--------------CQLIL-SKVFEPCHTVI 572
             + +     C          PA    +P               C+  L + V+  C + I
Sbjct: 2098 WKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRI 2157

Query: 573  PPLLFYEGCVFDRCHMTDL-DVVCSSLELYAALCASHDICID-WRGRTGHMCPFTCPADK 630
                F   C    C    L   +C +L+ + A C S  +    WR  +   CP  CPA  
Sbjct: 2158 DLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSS--FCPLECPAYS 2215

Query: 631  VYQPCGPSNPSYCYGNDSASLGA-LPEAGPITEGCFCPEGMTLFSTSAQVCVPTGCPRCL 689
             Y  C PS    C+  D    GA +P A    EGC C  G  L   S   CVP     C 
Sbjct: 2216 SYTNCLPSCSPSCWDLDGRCEGAKVPSA--CAEGCICQPGYVL---SEDKCVPRSQCGCK 2270

Query: 690  GPHGEPVKVGHT-VGMDCQE-CTCEAATWTLTCRPKLCPLPPACPL 733
              HG  + +G + V   C E C C      + C    CP    C L
Sbjct: 2271 DAHGGSIPLGKSWVSSGCTEKCVCTGG--AIQCGDFRCPSGSHCQL 2314



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 63/251 (25%), Positives = 99/251 (39%), Gaps = 45/251 (17%)

Query: 286  CSQDCQVVRGVDSDCPSTTLPPAPATS----PSISTSE----PVTELGCPNA----VPPR 333
            CS  C     +D  C    +P A A      P    SE    P ++ GC +A    +P  
Sbjct: 2224 CSPSCW---DLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIP-- 2278

Query: 334  KKGETWATPNCSEATCEGNNVISLRPRTCPRVEKPTCANGYPAVKVADQDGCCHHYQCQC 393
              G++W +  C+E        I      CP        +G      +D            
Sbjct: 2279 -LGKSWVSSGCTEKCVCTGGAIQCGDFRCP--------SGSHCQLTSDNSNSNCVSDKSE 2329

Query: 394  VCSGWGDPHYITFDGTYYTFLDNCTYVLVQQI-VPVYGHFRVLVDNYFCGAEDGLSCPRS 452
             CS +GDP Y+TFDG  Y      TYVL++ + V   G   +LV+       + +  PRS
Sbjct: 2330 QCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVE-----GRNKMDPPRS 2384

Query: 453  IILEYHQDRVVLTRKPVHGVMTN-----EIIFNNKVVSPGFRKN-GIVVSRIGVKMYATI 506
             I       V+ T   V+G         E++ NN+ ++  +R N  + V+  G ++Y  +
Sbjct: 2385 SIF---LQEVITT---VYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLY-LV 2437

Query: 507  PELGVQVMFSG 517
             +  + V F G
Sbjct: 2438 TDFELVVSFGG 2448


>gi|27881494 zonadhesin isoform 6 [Homo sapiens]
          Length = 2721

 Score =  129 bits (325), Expect = 1e-29
 Identities = 131/470 (27%), Positives = 179/470 (38%), Gaps = 88/470 (18%)

Query: 320  PVTELGCPNAVPPR-KKGETWATPNCSE-ATCEGNNVISLRPRTCPRVEKPTCANGYPAV 377
            P ++ GC +      K GE W  P C E   CE NN I  +P  C   E     +G    
Sbjct: 1475 PRSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIY-- 1532

Query: 378  KVADQDGCCHHYQCQCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVLVD 437
                  GC  H Q    C+  GDPHY+TFDG  + F+  CTYVL +   P +   +   D
Sbjct: 1533 ------GC--HAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTR---PCWSRSQ---D 1578

Query: 438  NYFCGAEDGLSCPRSIILEYHQDRVV------LTRKPVHG--VMTNEIIFNNKVVSPGFR 489
            +YF  +    +  R  ILE    + V      L+   + G  VM N     ++V  P + 
Sbjct: 1579 SYFVVSATNEN--RGGILEVSYIKAVHVTVFDLSISLLRGCKVMLN----GHRVALPVWL 1632

Query: 490  KNGIVVSRIGVKMYATIPELGVQVMFSGL-IFSVEVPFS----------KFANNT----- 533
              G V  R+   +       G+QV + G  +  V VP S           + NN+     
Sbjct: 1633 AQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNL 1692

Query: 534  ------EGQCXXXXXXXTTP-------------PAPCLPSPI-------CQLILSKV--F 565
                   G           P             P+ C  + +       C ++++    F
Sbjct: 1693 RPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGPF 1752

Query: 566  EPCHTVIPPLLFYEGCVFDRCHMT-DLDVVCSSLELYAALCASHDICIDWRGRTGHMCPF 624
              CH V+PP   +  CV  +C    D   +C SL+ YA+LCA       WR RT   CP 
Sbjct: 1753 SQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQAPAWRNRT--FCPM 1810

Query: 625  TCPADKVYQPCGPSNPSYCYGNDSASLGALPEAGPITEGCFCPEGMTLFSTSAQVCVPTG 684
             CP    Y PC    P  C   ++      P+A P  E C C +G  L  TS   CVP G
Sbjct: 1811 RCPPGSSYSPCSSPCPDTCSSINNPR--DCPKALPCAESCECQKGHILSGTS---CVPLG 1865

Query: 685  CPRCLGPHGEPVKVG---HTVGMDCQECTCEAATWTLTCRPKLCPLPPAC 731
               C  P G    VG   +T     + CTC      +TC    C     C
Sbjct: 1866 QCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHN-NITCFQSTCKPNQIC 1914



 Score = 99.8 bits (247), Expect = 1e-20
 Identities = 108/449 (24%), Positives = 156/449 (34%), Gaps = 81/449 (18%)

Query: 336  GETWATPNCSE-ATCEGNNVISLRPRTCPRVEKPTCANGYPAVKVADQDGCCHHYQCQCV 394
            G  W +PNC+E   C   + +  +   C         NG        Q GC H Y     
Sbjct: 1105 GAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNG--------QYGC-HPYAGTAT 1155

Query: 395  CSGWGDPHYITFDGTYYTFLDNCTYVLVQQI-VPVYGHFRVLVDNYFCGAEDGLSCPRSI 453
            C  +GDPHY+TFDG ++ F+  CTY+L Q         FRV   N   G ++G+SC   +
Sbjct: 1156 CLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQG-QEGVSCLSKV 1214

Query: 454  ILEYHQDRVVLTRKPVHGVMTNEIIFNNKVVSPGFRKNGIVVSRIGVKMYATIPELGVQV 513
             +   +  V L +          ++   +V  P     G+ +   G +      E G++V
Sbjct: 1215 YVTLPESTVTLLKG------RRTLVGGQQVTLPAIPSKGVFLGASG-RFVELQTEFGLRV 1267

Query: 514  MFSG---LIFSVEVPFS----KFANNTEGQCXXXXXXXTTPPA----------------- 549
             + G   L  +V   +S        N +G            PA                 
Sbjct: 1268 RWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDED 1327

Query: 550  ------PCLPSPICQLILSK----------------VFEPCHTVIPPLLFYEGCVFDRCH 587
                    + SP C   L                   FE C   +    F++ C+ D C 
Sbjct: 1328 QECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCG 1387

Query: 588  MTDLD-VVCSSLELYAALC--ASHDICIDWRGRTGHMCPFTCPADKVYQPCGPSNPSYCY 644
               L  ++C+ +      C  A H +   W  R  H CP  CP +  Y  C    P  C+
Sbjct: 1388 FQGLQHLLCTHMSTMTTTCQDAGHAV-KPW--REPHFCPMACPPNSKYSLCAKPCPDTCH 1444

Query: 645  GNDSASLGALPEAGPITEGCFCPEGMTLFSTSAQVCVPTGCPRCLGPHGEPVKVGHT-VG 703
               S        +    E C C  G  L   S   C+P     CL P G   KVG     
Sbjct: 1445 SGFSGMFC----SDRCVEACECNPGFVL---SGLECIPRSQCGCLHPAGSYFKVGERWYK 1497

Query: 704  MDCQE-CTCEAATWTLTCRPKLCPLPPAC 731
              C+E C CE+    + C+P  C     C
Sbjct: 1498 PGCKELCVCESNN-RIRCQPWRCRAQEFC 1525



 Score = 79.7 bits (195), Expect = 1e-14
 Identities = 127/526 (24%), Positives = 189/526 (35%), Gaps = 104/526 (19%)

Query: 283  YALCSQDC-QVVRGVDS--DCPSTTLPPAPATSP------SISTSEPVTELGCPN-AVPP 332
            Y+ CS  C      +++  DCP   LP A +         S ++  P+ + GC + A   
Sbjct: 1818 YSPCSSPCPDTCSSINNPRDCPKA-LPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSY 1876

Query: 333  RKKGETWATPN-CSE-ATCEGNNVISLRPRTCPRVEKPTCANGYPAVKVADQDGCCHHYQ 390
               GE W T N C+   TC  +N I+    TC   +     +G    + +          
Sbjct: 1877 HPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVG------- 1929

Query: 391  CQCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVLVDNYFCGAEDGLSCP 450
               VC   G+ HY++FDG+ ++  D CT VLV+   P        +       E G    
Sbjct: 1930 ---VCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAF 1986

Query: 451  R--SIILEYHQDRVVLTRKPVHGVMTNEIIFNNKVVS--PGFR-KNGIVVSRIGVKMYAT 505
            R   + ++ +  +V L +   H V+ N        +S  PG   K+  + S + +K    
Sbjct: 1987 RLHEVYIDIYDAQVTLQKG--HRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIK---- 2040

Query: 506  IPELGVQVMFSGL-IFSVEVPF--------------------------------SKFANN 532
               +GVQV F G  +  +E+P                                 S+F N+
Sbjct: 2041 ---IGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNS 2097

Query: 533  TEGQ-----CXXXXXXXTTPPAPCLPSPI--------------CQLIL-SKVFEPCHTVI 572
             + +     C          PA    +P               C+  L + V+  C + I
Sbjct: 2098 WKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRI 2157

Query: 573  PPLLFYEGCVFDRCHMTDL-DVVCSSLELYAALCASHDICID-WRGRTGHMCPFTCPADK 630
                F   C    C    L   +C +L+ + A C S  +    WR  +   CP  CPA  
Sbjct: 2158 DLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSS--FCPLECPAYS 2215

Query: 631  VYQPCGPSNPSYCYGNDSASLGA-LPEAGPITEGCFCPEGMTLFSTSAQVCVPTGCPRCL 689
             Y  C PS    C+  D    GA +P A    EGC C  G  L   S   CVP     C 
Sbjct: 2216 SYTNCLPSCSPSCWDLDGRCEGAKVPSA--CAEGCICQPGYVL---SEDKCVPRSQCGCK 2270

Query: 690  GPHGEPVKVGHT-VGMDCQE-CTCEAATWTLTCRPKLCPLPPACPL 733
              HG  + +G + V   C E C C      + C    CP    C L
Sbjct: 2271 DAHGGSIPLGKSWVSSGCTEKCVCTGG--AIQCGDFRCPSGSHCQL 2314



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 100/434 (23%), Positives = 148/434 (34%), Gaps = 115/434 (26%)

Query: 286  CSQDCQVVRGVDSDCPSTTLPPAPATS----PSISTSE----PVTELGCPNA----VPPR 333
            CS  C     +D  C    +P A A      P    SE    P ++ GC +A    +P  
Sbjct: 2224 CSPSCW---DLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIP-- 2278

Query: 334  KKGETWATPNCSEATCEGNNVISLRPRTCPRVEKPTCANGYPAVKVADQDGCCHHYQCQC 393
              G++W +  C+E        I      CP        +G      +D            
Sbjct: 2279 -LGKSWVSSGCTEKCVCTGGAIQCGDFRCP--------SGSHCQLTSDNSNSNCVSDKSE 2329

Query: 394  VCSGWGDPHYITFDGTYYTFLDNCTYVLVQQI-VPVYGHFRVLVDNYFCGAEDGLSCPRS 452
             CS +GDP Y+TFDG  Y      TYVL++ + V   G   +LV+       + +  PRS
Sbjct: 2330 QCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEG-----RNKMDPPRS 2384

Query: 453  IILEYHQDRVVLTRKPVHGVMTN-----EIIFNNKVVSPGFRKNG-IVVSRIGVKMY-AT 505
             I       V+ T   V+G         E++ NN+ ++  +R N  + V+  G ++Y  T
Sbjct: 2385 SIF---LQEVITT---VYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVT 2438

Query: 506  IPELGVQV------------MFSGLIFSVEVPFSKFANNT-------------------- 533
              EL V              M+ GL+  +   + K   N                     
Sbjct: 2439 DFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWE 2498

Query: 534  ------------------EGQCXXXXXXXTTPPAPCLPSPI-------CQLILSKV--FE 566
                              EGQ            + C P  +       C+++      F 
Sbjct: 2499 VKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFA 2558

Query: 567  PCHTVIPPLLFYEGCVFDRCHMTD----LDVVCSSLELYAALCASHDICI-DWRGRTGHM 621
             CH  + P  F E CV D C   D     ++ C  L  YA LC      +  WR RT  +
Sbjct: 2559 ACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRT--L 2616

Query: 622  CPFTCPADKVYQPC 635
            C   C    +  PC
Sbjct: 2617 CESPC----LQNPC 2626


>gi|134031945 SCO-spondin [Homo sapiens]
          Length = 5147

 Score =  127 bits (320), Expect = 4e-29
 Identities = 152/607 (25%), Positives = 210/607 (34%), Gaps = 132/607 (21%)

Query: 256  CFCNVADRLYPAGST--------IYRHRDL----AGHC-YYALCSQDCQVVRG---VDSD 299
            C C +  R Y  GS         I + R L    A HC   A C ++     G   +  D
Sbjct: 880  CPCQLGARRYAPGSATMKECNRCICQERGLWNCTARHCPSQAFCPRELVYAPGACLLTCD 939

Query: 300  CPSTTLPPAPATSPSISTSEPVTELGCPNAVPP-----RKKGETWATPN------CSEAT 348
             PS      PA S       P T L     VPP     R  G+ W  PN      C+   
Sbjct: 940  SPSAN-HSCPAGSTDGCVCPPGTVLLDERCVPPDLCPCRHSGQ-WYLPNATIQEDCNVCV 997

Query: 349  CEGNNVISLRPRTCPRVEKPTCANGYPAVKVADQDGCCHHYQCQCVCSGWGDPHYITFDG 408
            C G        R   R                              C   G PHY+TFDG
Sbjct: 998  CRGRQWHCTGQRRSGR------------------------------CQASGAPHYVTFDG 1027

Query: 409  TYYTFLDNCTYVLVQQIVPVYGHFRVLVDNYFCGAEDGLSCPRSIILEYHQDRVVLTRKP 468
              +T+   C Y+LV++     G F V   N  CGA  GL+C +++ +        L    
Sbjct: 1028 LAFTYPGACEYLLVRE---ASGLFTVSAQNLPCGAS-GLTCTKALAVR-------LEGTV 1076

Query: 469  VHGVMTNEIIFNNKVVSPG--FRKNGIVVSRIGVKMYATIPELGVQVMFSGLIFSVEVPF 526
            VH +    +  N   V+P   +   G+ + R G+ +  +   LG+ +++ G    +    
Sbjct: 1077 VHMLRGRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLST-HLGLTLLWDGGTRVLVQLS 1135

Query: 527  SKFANNTEGQCXXXXXXXTT--------------------------PPAPCLPSPI---- 556
             +F     G C       +                           P    LP P     
Sbjct: 1136 PQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLSPLCPEPGDLPHPCTMNT 1195

Query: 557  ---------CQLILSKVFEPCHTVIPPLLFYEGCVFDRCHMT---DLDVVCSSLELYAAL 604
                     C  +L  +F  CH  +PP   YE C++D C      D + +CS++  YA  
Sbjct: 1196 HRAGWARARCGALLQPLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADE 1255

Query: 605  CASHDICIDWRGRTGHMCPFTCPADKVYQPCGPSNPSYCYGNDSASLGALPEAGPITEGC 664
            CA H   + WR +   +C   C   +VY+ CGP+ P  C+       G   +     EGC
Sbjct: 1256 CARHGHHVRWRSQ--ELCSLQCEGGQVYEACGPTCPPTCH-EQHPEPGWHCQVVACVEGC 1312

Query: 665  FCPEGMTLFSTSAQVCVPTGCPRCLGPHGEPVKVGHTVGMDCQECTCEAATWTLTCRPKL 724
            FCPEG  L   +     P  CP   G +  P   G  +  DC  CTC+   W        
Sbjct: 1313 FCPEGTLLHGGAC--LEPASCPCEWGRNSFP--PGSVLQKDCGNCTCQEGQWHCGGDGGH 1368

Query: 725  C-PLPPACPLPGFVPVP---AAPQAGQCCPQYSCACNTSR--CPKPVGCPEGARAIPTYQ 778
            C  L PAC     +        P    C  Q  C   +    C  P GC EG     T  
Sbjct: 1369 CEELVPACAEGEALCQENGHCVPHGWLCDNQDDCGDGSDEEGCAAP-GCGEGQM---TCS 1424

Query: 779  EGACCPV 785
             G C P+
Sbjct: 1425 SGHCLPL 1431



 Score =  112 bits (280), Expect = 2e-24
 Identities = 123/485 (25%), Positives = 173/485 (35%), Gaps = 95/485 (19%)

Query: 386 CHHYQCQCVCSGWGDPHYITFDGTYYTFL--DNCTYVLVQQIVPVYGHFRVLVDNYFCGA 443
           C    C   C+  GD HY+TFDG  Y+F     C Y LVQ  V   G   +L+++   GA
Sbjct: 555 CAQALCPAECAVGGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVK--GQLLILLEH---GA 609

Query: 444 EDGLSCPRSIILEYHQDRVVLTRKPVHGVMTNEIIFNNKVVS-PGFRKNGIVVSRIGVKM 502
            D  SC  +I +      + L         +  ++ N + V  P     G+ V R     
Sbjct: 610 CDAGSCLHAISVSLEDTHIQLRD-------SGAVLVNGQDVGLPWIGAEGLSVRRAS-SA 661

Query: 503 YATIPELGVQVMFS-------------------GLIFS---------------VEVPFSK 528
           +  +   G QV++                    GL  +               VE   + 
Sbjct: 662 FLLLRWPGAQVLWGLSDPVAYITLDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVETSIAA 721

Query: 529 FANNTE----GQCXXXXXXXTTPPAP-----CLPSPICQLILSKVFEPCHTVIPPLLFYE 579
           FA+  +    G+C        +P              C ++ S VF+ CH ++    FY 
Sbjct: 722 FASKFQVAGKGRCPSEDSALLSPCTTHSQRHAFAEAACAILHSSVFQECHRLVDKEPFYL 781

Query: 580 GCVFDRCHMTD-LDVVCSSLELYAALCASHDICIDWRGRTGHMCPFTCPADKVYQPCGPS 638
            C+   C      D +C  L  YA  CA       WR +T  +CP  CP  + Y+ C P+
Sbjct: 782 RCLAAVCGCDPGSDCLCPVLSAYARRCAQEGASPPWRNQT--LCPVMCPGGQEYRECAPA 839

Query: 639 NPSYCYGNDSASLGALPEAGPITEGCFCPEGMTLFSTSAQVCVPTGCPRCLGPHGEPVKV 698
              +C   +        E G    GC CP G+ L+    Q   P+ CP  LG        
Sbjct: 840 CGQHCGKPEDCG-----ELGSCVAGCNCPLGL-LWDPEGQCVPPSLCPCQLG--ARRYAP 891

Query: 699 GHTVGMDCQECTC-EAATWTLTCRPKLCPLPPACP-----LPGFVPVPA-APQAGQCCPQ 751
           G     +C  C C E   W  T R   CP    CP      PG   +   +P A   CP 
Sbjct: 892 GSATMKECNRCICQERGLWNCTARH--CPSQAFCPRELVYAPGACLLTCDSPSANHSCP- 948

Query: 752 YSCACNTSRCPKPVGCPEGARAIPTYQEGACCPVQNCSWTVCSINGTLYQPGAVVSSSLC 811
              A +T  C     CP G   +    +  C P   C    C  +G  Y P A +    C
Sbjct: 949 ---AGSTDGCV----CPPGTVLL----DERCVPPDLCP---CRHSGQWYLPNATIQED-C 993

Query: 812 ETCRC 816
             C C
Sbjct: 994 NVCVC 998



 Score = 77.4 bits (189), Expect = 7e-14
 Identities = 108/452 (23%), Positives = 152/452 (33%), Gaps = 98/452 (21%)

Query: 658  GPITEGCFCPEGMTLFSTSAQVCVPTGCPRCLGPHGEP---VKVGHTVGMDCQECTCEAA 714
            GP   GC CP G  +       CVP    RC  P       +     V +DCQ CTC   
Sbjct: 4698 GPCRPGCRCPPGQLVQDGR---CVPISSCRCGLPSANASWELAPAQAVQLDCQNCTC--V 4752

Query: 715  TWTLTCRPKLCP-LPP-----ACPLP-------GFVPVPAAPQAGQCCPQYS---CACNT 758
              +L C  + CP L P     +C  P               P    C  Q +     CN 
Sbjct: 4753 NESLVCPHQECPVLGPWSAWSSCSAPCGGGTMERHRTCEGGPGVAPCQAQDTEQRQECNL 4812

Query: 759  SRCPKPVGCPEG------ARAIPTY----QEGACCPVQNCSWTVCSINGTLYQPGAVVSS 808
              CP+   CP G      A + P      Q GA C  + C        G L   G  V  
Sbjct: 4813 QPCPE---CPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPP 4869

Query: 809  SLCETCRCELPGG------------PPSDAFVVSCETQIC----------NTHCPVGFEY 846
            + C   +  LP G            PP      +C   +C          +   P G  +
Sbjct: 4870 TACPCTQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQVPPGETW 4929

Query: 847  QEQSGQCCGTCVQVACVTNTSKSPAH---------LFYPGETWSDAG-----NHCV---- 888
            Q+ +    G C Q     N +K+ ++         +  PG   S AG     +HC     
Sbjct: 4930 QQVAPGELGLCEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDHCECWHL 4989

Query: 889  ----------THQCEK--HQDGLVVVTTKKACPPLSCSLDEARMSKDG-CCRFCPPPPPP 935
                         CE      G  V T  + C PL+C+  E  + + G CC  C    P 
Sbjct: 4990 GRPHLPGSEWQEACESCLCLSGRPVCT--QHCSPLTCAQGEEMVLEPGSCCPSCRREAP- 5046

Query: 936  YQNQSTCAVYHRSLIIQQQGCSSSEPVRLAYCRGNCGDSSSMYSLEGNTVEHRCQCCQ-- 993
             + QS        L    +G    + V ++YC G C  SS+    E   ++ +C CC   
Sbjct: 5047 -EEQSPSCQLLTELRNFTKGTCYLDQVEVSYCSGYC-PSSTHVMPEEPYLQSQCDCCSYR 5104

Query: 994  -ELRTSLRNVTLHCTDGSSRAFSYTEVEECGC 1024
             +  + +R + L C  G +       +  C C
Sbjct: 5105 LDPESPVRILNLRCLGGHTEPVVLPVIHSCQC 5136



 Score = 67.0 bits (162), Expect = 9e-11
 Identities = 69/242 (28%), Positives = 95/242 (39%), Gaps = 30/242 (12%)

Query: 622  CP-FTCPADKVYQPCGPSNPSYCYGNDSASLGALPEAGPI-TEGCFCPEGMTLFSTSAQV 679
            CP  TC  + ++QPC P  P  C  +D +     P   P  + GC+CPEG  L S     
Sbjct: 1807 CPNATCSGELMFQPCAPC-PLTC--DDISGQVTCPPDWPCGSPGCWCPEGQVLGSEG--W 1861

Query: 680  CV-PTGCPRCLGPHGEPVKVGHTVGMDCQECTCEAATWTLTCRPKLCPLPPACPLP-GFV 737
            CV P  CP CL   G     G  +  DCQ C C+        RP+ C L P C +  G+ 
Sbjct: 1862 CVWPRQCP-CL-VDGARYWPGQRIKADCQLCICQDG------RPRRCRLNPDCAVDCGWS 1913

Query: 738  P-VPAAPQAGQCCPQ-YSCACNTSRCPKPVGCPEGARAIPTYQEGACCPVQNCSWTVCSI 795
               P A   G C  Q    +  +S  P+P G     R I  +++   C  + C    C  
Sbjct: 1914 SWSPWAKCLGPCGSQSIQWSFRSSNNPRPSGRGRQCRGI--HRKARRCQTEPCEG--CEH 1969

Query: 796  NGTLYQPGAVVSSSLCETCRCELPGGPPSDAFVVSCETQICNTHCPVGFEYQEQSGQCCG 855
             G +++ G       C  C+C              C        CP G+   E +G+ C 
Sbjct: 1970 QGQVHRVGERWHGGPCRVCQC-------LHNLTAHCSPYCPLGSCPQGWVLVEGTGESCC 2022

Query: 856  TC 857
             C
Sbjct: 2023 HC 2024



 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 50/179 (27%), Positives = 64/179 (35%), Gaps = 18/179 (10%)

Query: 556 ICQLILSKVFEPCHTVIPPLLFYEGCVFDRC--------HMTDLDVVCSSLELYAALCAS 607
           +C  +L   F  CH  + P  ++E C+F  C               VC++   Y   CA 
Sbjct: 393 VCHQLLEGPFGQCHAQVSPAEYHEACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACAR 452

Query: 608 HDICIDWRGRTGHMCPFTCPADKVYQPCGPSNPSYCYGNDSASLGALPEAGPITEGCFCP 667
             I I WR + G  C   CP  ++Y  C    P  C         +  E      GC CP
Sbjct: 453 RHIHIRWR-KPG-FCERLCPGGQLYSDCVSLCPPSCEAVGQGEEESCRE--ECVSGCECP 508

Query: 668 EGMTLFSTSAQVCVPTGCPRCLGPHGEPVKVGHTVGMDCQECTCEAATWTLTCRPKLCP 726
            G+    T   +CVP     C       V  G TV   C  C C    W   C   LCP
Sbjct: 509 RGLFWNGT---LCVPAAHCPCYYCRQRYVP-GDTVRQLCNPCVCRDGRW--HCAQALCP 561



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 83/322 (25%), Positives = 111/322 (34%), Gaps = 65/322 (20%)

Query: 622  CPFT-CPADK--VYQPCGPSNPSYCYGNDSASLGALPEAGPITEGCFCPEGMTLFSTSAQ 678
            CP T C A +   Y PCGP  P  C           P       GC+CP G  L S  A 
Sbjct: 3306 CPVTNCTAIEGAEYSPCGPPCPRSCDDLVHCVWRCQP-------GCYCPPGQVLSSNGA- 3357

Query: 679  VCVPTGCPRCLG-----PHGEPVKVGHTVGMDCQECTCEAATWTLTCRPKLCPLPPA-CP 732
            +CV  G   CL       H    ++    G  C  CTC      L C    CP+P   CP
Sbjct: 3358 ICVQPGHCSCLDLLTGQRHHPGARLARPDG--CNHCTC--LEGRLNCTDLPCPVPGGWCP 3413

Query: 733  LPGFVPVPAAPQAGQC-CPQYSCACNTSRCPKPVGCP---EGARAIPTYQEGACCPVQNC 788
               +  + + P  GQ      +CAC T   P+  G P   E   A   +Q  AC      
Sbjct: 3414 WSEWT-MCSQPCRGQTRSRSRACACPT---PQHGGAPCTGEAGEAGAQHQREAC-----P 3464

Query: 789  SWTVCSINGTL--YQPGAVVSSSLCETCRCELPGGPPSDAFVVSCETQICNTHCPVGFEY 846
            S+  C ++G    + P +     L ++ R      PP+      C      +        
Sbjct: 3465 SYATCPVDGAWGPWGPWSPCDMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSR-----PC 3519

Query: 847  QEQSGQC--CGTCVQVACVTNTSKSPAHLFYPGETWSDAGNHCVTHQCEKHQDGLVVVTT 904
            QE S QC  CG                     G++    G  C    C+    G V    
Sbjct: 3520 QENSTQCTDCG--------------------GGQSLHPCGQPC-PRSCQDLSPGSVCQPG 3558

Query: 905  KKACPPLSCSLDEARMSKDGCC 926
               C P +C     ++S+DG C
Sbjct: 3559 SVGCQP-TCGCPLGQLSQDGLC 3579



 Score = 50.4 bits (119), Expect = 9e-06
 Identities = 107/409 (26%), Positives = 141/409 (34%), Gaps = 84/409 (20%)

Query: 623  PFTCPADKVYQPCGPSNPSYCYGNDSASLGALPEAGPITEGCFCPEGMTLFSTSAQVCVP 682
            P  CP DK +  C    P+ C    SA  G      P   GC CP GM L +    VCVP
Sbjct: 3087 PGMCPRDKQWLDCA-QGPASC-AELSAPRGTNQTCHP---GCHCPSGMLLLN---NVCVP 3138

Query: 683  T-GCPRCLGPHGEPVKVGHTVGMDCQECTCEAATWTLTCRPKLCP--LPPACPLPGFVPV 739
            T  CP     H  P   G TV   C+ C+C +      C    C    P   P   +   
Sbjct: 3139 TQDCPCAHEGHLYP--PGSTVVRPCENCSCVSGL-IANCSSWPCAEGEPTWSPWTPWSQC 3195

Query: 740  PAAPQAGQCCPQYSCACNTSRCPKPVGCPEGARAIPT------YQEGACCPVQNCS---- 789
             A+    +C     CA + S  P  V  P    A PT        E   C +Q C     
Sbjct: 3196 SASCGPARCHRHRFCARSPSAVPSTV-APLPLPATPTPLCSGPEAEEEPCLLQGCDRAGG 3254

Query: 790  ------WTVC--SINGTLY-------QPGAVVSSSLCETCRCELPGGPPSDAFVVSCETQ 834
                  W+ C  S  G L        QP        CE        GP +   V  C+  
Sbjct: 3255 WGPWGPWSHCSRSCGGGLRSRTRACDQPPPQGLGDYCE--------GPRAQGEV--CQAL 3304

Query: 835  ICN-THCPV--GFEYQEQSGQCCGTCVQ-VACVTNTSKSPAHLFYPGETWSDAGNHCVTH 890
             C  T+C    G EY      C  +C   V CV      P     PG+  S  G  CV  
Sbjct: 3305 PCPVTNCTAIEGAEYSPCGPPCPRSCDDLVHCVWRC--QPGCYCPPGQVLSSNGAICVQ- 3361

Query: 891  QCEKHQDGLVVVTTKKACPPLSCSLDEARMSK-DGC-----------CRFCPPPPP---- 934
                H   L ++T ++  P        AR+++ DGC           C   P P P    
Sbjct: 3362 --PGHCSCLDLLTGQRHHP-------GARLARPDGCNHCTCLEGRLNCTDLPCPVPGGWC 3412

Query: 935  PYQNQSTCAVYHRSLI-IQQQGCSSSEPVR-LAYCRGNCGDSSSMYSLE 981
            P+   + C+   R     + + C+   P    A C G  G++ + +  E
Sbjct: 3413 PWSEWTMCSQPCRGQTRSRSRACACPTPQHGGAPCTGEAGEAGAQHQRE 3461



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 70/275 (25%), Positives = 94/275 (34%), Gaps = 79/275 (28%)

Query: 657  AGPITEGCFCPEGMTLFSTSAQVCVP-TGCPRCLGPHGEPVKVGHTVGMDCQECTCEAAT 715
            +G   EGC CP G+ L  T    C+P + CP  +G   +   V   +G +C +C CE   
Sbjct: 2649 SGHCVEGCRCPPGLLLHDTR---CLPLSECPCLVGEELKWPGVSFLLG-NCSQCVCEKG- 2703

Query: 716  WTLTCRPKLCPLP--------------------------PACPLP--GFVPVPAAPQAGQ 747
              L C+P  CPLP                          P+ P    G  P     Q  Q
Sbjct: 2704 -ELLCQPGGCPLPCGWSAWSSWAPCDRSCGSGVRARFRSPSNPPAAWGGAPCEGDRQELQ 2762

Query: 748  CC------------PQYSCACNTSRCPKPVGCP---EGARAIPTYQEGAC---------- 782
             C            P  S +  +  C  P G P     +R  P+  + +C          
Sbjct: 2763 GCHTVCGTEVFGWTPWTSWSSCSQSCLAPGGGPGWRSRSRLCPSPGDSSCPGDATQEEPC 2822

Query: 783  ----CPVQN-----CSWTVCS--INGTLYQPGAVVSSSLCETCRCELPGGPPSDAFVVSC 831
                CPV +       W+ CS   +G +   G   SS       C  P     D     C
Sbjct: 2823 SPPVCPVPSIWGLWAPWSTCSAPCDGGIQTRGRSCSSLAPGDTTCPGPHSQTRD-----C 2877

Query: 832  ETQICNTHCPVG--FEYQEQSGQCCGTCVQVACVT 864
             TQ C   CP    F   EQ  Q  G C ++ C+T
Sbjct: 2878 NTQPCTAQCPENMLFRSAEQCHQEGGPCPRL-CLT 2911



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 16/34 (47%), Positives = 20/34 (58%)

Query: 388 HYQCQCVCSGWGDPHYITFDGTYYTFLDNCTYVL 421
           H +    C+ W   HY TFDG +Y FL  CTY+L
Sbjct: 188 HQRPSATCASWSGFHYRTFDGRHYHFLGRCTYLL 221



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 63/255 (24%), Positives = 86/255 (33%), Gaps = 56/255 (21%)

Query: 614  WRGRTGHMCPF----TCPADKVYQPCGPSNPSYCYGNDSASLGALPEAGPITEGCFCPEG 669
            WR R+  +CP     +CP D   +   P +P  C       L A P +   T    C  G
Sbjct: 2797 WRSRS-RLCPSPGDSSCPGDATQEE--PCSPPVCPVPSIWGLWA-PWS---TCSAPCDGG 2849

Query: 670  MTLFSTSAQVCVPTGCPRCLGPHGEPVKVGHTVGMDCQECTCEAATWTLTCRPKLC---- 725
            +     S     P G   C GPH +      T   + Q CT +     L    + C    
Sbjct: 2850 IQTRGRSCSSLAP-GDTTCPGPHSQ------TRDCNTQPCTAQCPENMLFRSAEQCHQEG 2902

Query: 726  -PLPPACPLPGFVPVPAAPQAGQCCPQYSCACNTSRCPKPVGCPEGARAIPTYQEGACCP 784
             P P  C   G    P     G C P     C          CP G          +C P
Sbjct: 2903 GPCPRLCLTQG----PGIECTGFCAP----GCT---------CPPGL----FLHNASCLP 2941

Query: 785  VQNCSWTVCSINGTLYQPGAVVSSSLCETCRCELPG--GPPSDAFVVSCE------TQIC 836
               C    C ++G LY  GA+     C  C C + G     S+   V+C         +C
Sbjct: 2942 RSQCP---CQLHGQLYASGAMARLDSCNNCTC-VSGKMACTSERCPVACGWSPWTLWSLC 2997

Query: 837  NTHCPVGFEYQEQSG 851
            +  C VG   + ++G
Sbjct: 2998 SCSCNVGIRRRFRAG 3012



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 85/338 (25%), Positives = 112/338 (33%), Gaps = 97/338 (28%)

Query: 626  CPADKVYQPCGPSNPSYCYGNDSASLGALPEAGPI--TEGCFCPEGMTLFSTSAQVCVPT 683
            C   +   PCG   P  C      S G++ + G +     C CP G     +   +CVP 
Sbjct: 3529 CGGGQSLHPCGQPCPRSC---QDLSPGSVCQPGSVGCQPTCGCPLGQL---SQDGLCVPP 3582

Query: 684  GCPRCLGPHG-------------------EPVKVGHTVGMDCQECTCEAATWTLTCRPKL 724
               RC    G                   E ++ G  V   C  CTC A           
Sbjct: 3583 AHCRCQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQ------- 3635

Query: 725  CPLPPACPLPGFVPVPAAPQAGQCCPQYSCA----CNTSRCPKPVGCPEGARAIPTYQEG 780
            C   P CP PG   V ++    + C   SC       + RC +P  CP  AR      + 
Sbjct: 3636 CQEVPDCPDPG---VWSSWGPWEDC-SVSCGGGEQLRSRRCARP-PCPGPAR------QS 3684

Query: 781  ACCPVQNCSWTVCSINGTLY---QPGAVVSSSLCETCRCELPGGPPSDAFV---VSCETQ 834
              C  Q C    C   G LY   QPG                G P S A V   V C ++
Sbjct: 3685 RTCSTQVCREAGCPA-GRLYRECQPG---------------EGCPFSCAHVTQQVGCFSE 3728

Query: 835  IC--NTHCPVG-FEYQEQSGQCCGTCVQVACVTN----TSKSPAHLFYPGETWSDAGNHC 887
             C    HCP G F+++    Q C  CV  A +      T   P     PG+   D+G   
Sbjct: 3729 GCEEGCHCPEGTFQHRLACVQEC-PCVLTAWLLQELGATIGDPGQPLGPGDE-LDSGQ-- 3784

Query: 888  VTHQCEKHQDGLVVVTTKKACPPLSCSLDEARMSKDGC 925
                           T + +C   SC+  +   S D C
Sbjct: 3785 ---------------TLRTSCGNCSCAHGKLSCSLDDC 3807



 Score = 40.4 bits (93), Expect = 0.009
 Identities = 49/214 (22%), Positives = 66/214 (30%), Gaps = 34/214 (15%)

Query: 622  CPFTCPADKVYQPCGPSNPSYCYGNDSASLGALPEAGPITEGCFCPEGMTLFSTSAQVCV 681
            C   CPA      C    P  C  +D        +     +GC CP+G          CV
Sbjct: 4058 CEAGCPAGMEVVTCANRCPRRC--SDLQEGIVCQDDQVCQKGCRCPKGSLEQDGG---CV 4112

Query: 682  PTGCPRCLGPHGEPVKVGHTVGMDCQECTCEAATWTLTCRPKLCPLPPACPLPGFVP-VP 740
            P G   C    G     G      C  C+C+A   + T +P  CP P  C    +    P
Sbjct: 4113 PIGHCDCTDAQGHSWAPGSQHQDACNNCSCQAGQLSCTAQP--CPPPTHCAWSHWSAWSP 4170

Query: 741  AAPQAGQCCPQYSCACNTS---------------RCPKPVGCPEGARAIPTYQEGACCPV 785
             +   G    Q     +TS                CP+P  CP      P   +G     
Sbjct: 4171 CSHSCGPRGQQSRFRSSTSGSWAPECREEQSQSQPCPQP-SCP------PLCLQGTRSRT 4223

Query: 786  QNCSWTVCSINGTLYQPGAVVSSSLCETCRCELP 819
               SW    + G   +        +CE   C +P
Sbjct: 4224 LGDSW----LQGECQRCSCTPEGVICEDTECAVP 4253



 Score = 38.9 bits (89), Expect = 0.026
 Identities = 78/350 (22%), Positives = 107/350 (30%), Gaps = 65/350 (18%)

Query: 608  HDICID-WRGRTGHMCPFTCPADKVYQPCGPSNPSYCYGNDSASLGALPEAGPITEGCFC 666
            H +C+D   GR     P  C A    Q   P +P  C  +   SL        +     C
Sbjct: 4577 HRLCLDPATGRPWTGAPHLCTAPLSQQRLCP-DPGACPDSCQWSLWGPWSPCQVP----C 4631

Query: 667  PEGMTLFSTSAQVCVPTGCPRCLGPHGEPVKVGHTVGMDCQECTCEAATWTLTCRPKLCP 726
              G  L    A+     GC        EP       G  C EC  +   +TL C      
Sbjct: 4632 SGGFRLRWREAEALCGGGCR-------EPWAQESCNGGPCPECEAQDTVFTLDC------ 4678

Query: 727  LPPACPLPGFVPVPAAPQAGQCCPQYSCA-------CNTSRCPKPVGCPEGARAIPTYQE 779
                              A QC   +SCA       C    C     CP G       Q+
Sbjct: 4679 ------------------ANQC--PHSCADLWDRVQCLQGPCRPGCRCPPGQLV----QD 4714

Query: 780  GACCPVQNCSWTVCSINGTLYQPGAVVSSSLCETCRC--ELPGGPPSDAFVVSCETQICN 837
            G C P+ +C   + S N +     A      C+ C C  E    P  +  V+   +   +
Sbjct: 4715 GRCVPISSCRCGLPSANASWELAPAQAVQLDCQNCTCVNESLVCPHQECPVLGPWSAWSS 4774

Query: 838  THCPVGFEYQEQSGQCCGTCVQVACVTNTSK-------SPAHLFYPGETWSDAGNHCVTH 890
               P G    E+   C G      C    ++        P     PG+  S     C   
Sbjct: 4775 CSAPCGGGTMERHRTCEGGPGVAPCQAQDTEQRQECNLQPCPECPPGQVLSACATSCPC- 4833

Query: 891  QCEKHQDGLVVVTTKKACPPLSCSLDEARMSKDGCCRFCPPPPPPYQNQS 940
             C   Q G + V  ++ C P  C     ++  +G C   PP   P    S
Sbjct: 4834 LCWHLQPGAICV--QEPCQP-GCGCPGGQLLHNGTC--VPPTACPCTQHS 4878



 Score = 37.7 bits (86), Expect = 0.058
 Identities = 63/247 (25%), Positives = 88/247 (35%), Gaps = 42/247 (17%)

Query: 626  CPADKVYQPCGPSN--PSYCYGNDSASLGALPEAGPITEGCFCPEGM---TLFSTSAQVC 680
            CPA ++Y+ C P    P  C  + +  +G   E     EGC CPEG     L       C
Sbjct: 3697 CPAGRLYRECQPGEGCPFSC-AHVTQQVGCFSEG--CEEGCHCPEGTFQHRLACVQECPC 3753

Query: 681  VPT-----------GCP-RCLGPHGEPVKVGHTVGMDCQECTCEAATWTLTCRPKLCPLP 728
            V T           G P + LGP G+ +  G T+   C  C+C  A   L+C    C   
Sbjct: 3754 VLTAWLLQELGATIGDPGQPLGP-GDELDSGQTLRTSCGNCSC--AHGKLSCSLDDCFEA 3810

Query: 729  PACPLPGFVPVPAAPQAGQCCPQYSCACNTSRC--PKPVGCPEGARAIPTYQEGACCPVQ 786
                  GF P        + C        + +C    P    +G R     ++   CP  
Sbjct: 3811 DG----GFGPWSPWGPCSRSCGGLGTRTRSRQCVLTMPTLSGQGCRG---PRQDLECPSP 3863

Query: 787  NC----SWTVCSINGTLYQPGAVVSSSLCETCRCELPGGPPSDAFVVSCETQICNTHCPV 842
            +C      TV  + G     G   S S C    C  P  P          T++C  +C +
Sbjct: 3864 DCPGAEGSTVEPVTGLPGGWGPWSSWSPCSR-SCTDPARP-----AWRSRTRLCLANCTM 3917

Query: 843  GFEYQEQ 849
            G   QE+
Sbjct: 3918 GDPLQER 3924



 Score = 35.4 bits (80), Expect = 0.29
 Identities = 98/458 (21%), Positives = 144/458 (31%), Gaps = 112/458 (24%)

Query: 625  TCPADKVYQPCGPSNPSYCYGNDSASLGALPEAGPITEGCFCPEGMTLFSTSAQVC---- 680
            +C  D  ++  G   P   +G  S S G L   G  T    C   +T+ + S Q C    
Sbjct: 3801 SCSLDDCFEADGGFGPWSPWGPCSRSCGGL---GTRTRSRQCV--LTMPTLSGQGCRGPR 3855

Query: 681  --VPTGCPRCLGPHGEPVK--VGHTVGMD-------CQECTCEAATWTLTCRPKLC---- 725
              +    P C G  G  V+   G   G         C     + A      R +LC    
Sbjct: 3856 QDLECPSPDCPGAEGSTVEPVTGLPGGWGPWSSWSPCSRSCTDPARPAWRSRTRLCLANC 3915

Query: 726  ----PLPPA-CPLPGFVPVPAAPQ----AGQC-----CPQYSCA--CNTS--------RC 761
                PL    C LP    +P  P     AG C      P   C+  C           R 
Sbjct: 3916 TMGDPLQERPCNLPSCTELPVCPGPGCGAGNCSWTSWAPWEPCSRSCGVGQQRRLRAYRP 3975

Query: 762  PKPVG--CPEGARAIPTYQEGACCPVQNC------------SWTVCSINGTLYQPGAVVS 807
            P P G  CP     +  YQE   C ++ C            SW   S  G     G  + 
Sbjct: 3976 PGPGGHWCPN---ILTAYQERRFCNLRACPVPGGWSRWSPWSWCDRSCGG-----GQSLR 4027

Query: 808  SSLCETCRCELPGGPPSDAFVVS--CETQICNTHCPVGFEYQEQSGQCCGTCVQV----- 860
            S  C +   +  G P +     +  C    C   CP G E    + +C   C  +     
Sbjct: 4028 SRSCSSPPSKNGGAPCAGERHQARLCNPMPCEAGCPAGMEVVTCANRCPRRCSDLQEGIV 4087

Query: 861  ----------------------ACV----TNTSKSPAHLFYPGETWSDAGNHCVTHQCEK 894
                                   CV     + + +  H + PG    DA N+C    C+ 
Sbjct: 4088 CQDDQVCQKGCRCPKGSLEQDGGCVPIGHCDCTDAQGHSWAPGSQHQDACNNC---SCQA 4144

Query: 895  HQDGLVVVTTKKACPPLSCSLDEARMSKDGCCRFCPPPPPPYQNQSTCAVYHRSLIIQQQ 954
             Q    +  T + CPP +        +   C   C P     + +S+ +        ++Q
Sbjct: 4145 GQ----LSCTAQPCPPPTHCAWSHWSAWSPCSHSCGPRGQQSRFRSSTSGSWAPECREEQ 4200

Query: 955  GCSSSEPVRLAYCRGNCGDSSSMYSLEGNTVEHRCQCC 992
              S S+P     C   C   +   +L  + ++  CQ C
Sbjct: 4201 --SQSQPCPQPSCPPLCLQGTRSRTLGDSWLQGECQRC 4236



 Score = 33.9 bits (76), Expect = 0.84
 Identities = 104/466 (22%), Positives = 144/466 (30%), Gaps = 104/466 (22%)

Query: 625  TCPADKVYQPCGPSNPSYCYGNDSASLGALPEAGPITEGCFCPEGMTLFSTSAQVCVPTG 684
            +C     +  CG      C  + S  L    +  P   GC+CP+G+      A  C+P  
Sbjct: 4422 SCTPPFEFHACGSPCAGLCATHLSHQL--CQDLPPCQPGCYCPKGLL---EQAGGCIPPE 4476

Query: 685  CPRC----LGPHGEPVKVGHTVGMDCQECTCEAATWTLTCRPKLCP-LPPACPLPGFVPV 739
               C        G  +  G  + + C+EC C      L C  + C  L P      + P 
Sbjct: 4477 ECNCWHTSAAGAGMTLAPGDRLQLGCKECECRRG--ELHCTSQGCQGLLPLSEWSEWSPC 4534

Query: 740  PAAPQAGQCCPQYSCACNTSRCPKPVG-CPEGARAIPTYQEG---ACCPVQNCSWTVCSI 795
                      P    A        P G  P  A  + + Q        P     WT    
Sbjct: 4535 GPCLPPSALAPASRTALEEHWLRDPTGLSPTLAPLLASEQHRHRLCLDPATGRPWT---- 4590

Query: 796  NGTLYQPGA--VVSSSLCETCRCELPGGPPSDAFVVSCETQI------CNTHCPVGF--E 845
                   GA  + ++ L +   C  PG  P      SC+  +      C   C  GF   
Sbjct: 4591 -------GAPHLCTAPLSQQRLCPDPGACPD-----SCQWSLWGPWSPCQVPCSGGFRLR 4638

Query: 846  YQEQSGQCCGTCVQVACVTNTSKSPAHLFYPGETWSDAGNHCVTHQCEKHQDGLVVVTTK 905
            ++E    C G C +                P    S  G  C   +CE  QD +  +   
Sbjct: 4639 WREAEALCGGGCRE----------------PWAQESCNGGPC--PECEA-QDTVFTLDCA 4679

Query: 906  KACPPLSCSLDEARMSKDGCCR---FCPPPPPPYQNQSTCAVYHRSLIIQQQGCSSSEPV 962
              CP     L +      G CR    CPP                  ++Q   C     V
Sbjct: 4680 NQCPHSCADLWDRVQCLQGPCRPGCRCPP----------------GQLVQDGRC-----V 4718

Query: 963  RLAYCRGNCGDSSSMYSLE---GNTVEHRCQCCQELRTSLRNVTLHC-TDGSSRAFSYTE 1018
             ++ CR  CG  S+  S E      V+  CQ C  +  SL      C   G   A+S   
Sbjct: 4719 PISSCR--CGLPSANASWELAPAQAVQLDCQNCTCVNESLVCPHQECPVLGPWSAWSSCS 4776

Query: 1019 VEECG---------CMGRRCPAP---GDTQHSEEAEPEPSQEAESG 1052
               CG         C G    AP    DT+  +E   +P  E   G
Sbjct: 4777 A-PCGGGTMERHRTCEGGPGVAPCQAQDTEQRQECNLQPCPECPPG 4821



 Score = 32.7 bits (73), Expect = 1.9
 Identities = 43/193 (22%), Positives = 64/193 (33%), Gaps = 47/193 (24%)

Query: 177  CRNQDQQGPFK-MCLNYEVRVLCCETPRGCPVTSVTPYGTSPTNALYPSLSTSMVSASVA 235
            C  Q   GP   MC   +  + C + P  C   S  P GT+ T   +P            
Sbjct: 3077 CGLQPCAGPVPGMCPRDKQWLDCAQGPASCAELSA-PRGTNQT--CHPGCHCP------- 3126

Query: 236  STSVASSSVASSSVAYSTQTCFCNVADRLYPAGSTIYRHRDLAGHCYYALCSQDCQVVRG 295
                 S  +  ++V   TQ C C     LYP GST+ R              ++C  V G
Sbjct: 3127 -----SGMLLLNNVCVPTQDCPCAHEGHLYPPGSTVVRP------------CENCSCVSG 3169

Query: 296  VDSDCPSTTLPPAPATSPSISTSEPVTELGCPNAVPPRKKGETWATPNCSEATCEGNNVI 355
            + ++C S    P     P+ S   P ++                 + +C  A C  +   
Sbjct: 3170 LIANCSSW---PCAEGEPTWSPWTPWSQ----------------CSASCGPARCHRHRFC 3210

Query: 356  SLRPRTCPRVEKP 368
            +  P   P    P
Sbjct: 3211 ARSPSAVPSTVAP 3223



 Score = 31.6 bits (70), Expect = 4.2
 Identities = 60/253 (23%), Positives = 81/253 (32%), Gaps = 54/253 (21%)

Query: 703  GMDCQECTCEAATWTLTCRPKLCPLPPACPLPGFVP---VPAAPQAGQCCPQYSCACNTS 759
            G D + C      W     P L  L  A  +P  +P   +P  P +   C     +C + 
Sbjct: 2419 GSDERHCARNLLMWL----PSLPALWAASTVPFMMPTMALPGLPASRALCSPSQLSCGSG 2474

Query: 760  -------RCPKPVGCPEGARAIPTYQEGACCPVQNCSWTVCSINGTLYQPGAVVSSSLCE 812
                   RC     C +G+       E  C       W+V S        G  ++    E
Sbjct: 2475 ECLSAERRCDLRPDCQDGS------DEDGCVDCVLAPWSVWS--SCSRSCGLGLTFQRQE 2526

Query: 813  TCRCELPGGP-PSDAFVVSCETQICNTH-CPVGFEYQ--EQSGQCCGTCV------QVAC 862
              R  LPGG  P D F     +Q C    CPV   +   E  G C  +C       Q +C
Sbjct: 2527 LLRPPLPGGSCPRDRF----RSQSCFVQACPVAGAWAMWEAWGPCSVSCGGGHQSRQRSC 2582

Query: 863  VTNTSKSPAHLFYPGETWSDAGNHCVTHQCEKHQDGLVVVTTKKACPPLSCSLDEARMSK 922
            V    K+              G  C     E+   GL     +       C L    +S 
Sbjct: 2583 VDPPPKN-------------GGAPCPGASQERAPCGL-----QPCSGGTDCELGRVYVSA 2624

Query: 923  DGCCRFCPPPPPP 935
            D C +   PP PP
Sbjct: 2625 DLCQKGLVPPCPP 2637


>gi|239755901 PREDICTED: chromosome 12 open reading frame 64 [Homo
            sapiens]
          Length = 2250

 Score =  114 bits (286), Expect = 4e-25
 Identities = 163/714 (22%), Positives = 233/714 (32%), Gaps = 167/714 (23%)

Query: 303  TTLPPAPATSPSISTSE--------------PVTELGCPNAVPPRKKGETWATPNCSEAT 348
            T +PPA  T P  +  E              P T L C     P+K    +   +CS+  
Sbjct: 1341 TLMPPAKPTVPMFTVWEMITPSDITVFDMLTPTTGLECE----PQKFDPVY---DCSQYI 1393

Query: 349  CEGNN-VISLRPRTCPR-VEKPTCANGYPAVKVADQDGCCHHYQCQCVCSGWGDPHYITF 406
            C      +      CP+ VE P C      V+V + D CC  ++C C CS   +   ITF
Sbjct: 1394 CLNMEWQLYNWSLNCPKDVEMPDCGFRGRPVQV-NSDICCPEWECPCRCSMLSELSIITF 1452

Query: 407  DGTYYTFLDNCTYVLVQQIVP---VYGHFRVLVDNYFCGAEDGLSCPRSIILEYHQDRVV 463
            DG         +Y+LV+  +P   +  H      N          C + + +     +++
Sbjct: 1453 DGNNAALYSMASYILVR--IPGEIIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKII 1510

Query: 464  LTRKPVHGVMTNEIIFNNKVVSPGFRKNGIVVSRIGVKMYATIPELGVQVMFSGLIFSVE 523
            + R      +  ++  ++ VV   F    + +   G  MY      G+ + +S L   ++
Sbjct: 1511 VNR------LARKVEVDSIVVPLPFSSQELSIEDSG-SMYVITTPAGLIIKWSHLTGIID 1563

Query: 524  VPFS---KFANNTEGQCXXXXXXXTT---------------------------------- 546
            + F      ++ TEG C                                           
Sbjct: 1564 IHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTMR 1623

Query: 547  -PPAPCLPSPICQ---LILSKVFEPCHTVIPPLLFYEGCVFDRCHMTDLDVVCSSLELYA 602
             P   C      Q   L+  ++F PCH  + P  F E    +  +  + +  C +L  Y 
Sbjct: 1624 RPVRNCTEHDCSQCIDLLNRRIFIPCHDKVSPEDFCEKMWINYTYFWNYE--CDALSAYV 1681

Query: 603  ALCASHDICIDWRGRTGHMCPFTCPADKVYQPC-GPSNPSYC-----YGNDSASLGALPE 656
            ALC   DICI W  RT   C  +CP  K YQPC  P     C     YG+ S        
Sbjct: 1682 ALCNKFDICIQW--RTPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSCL------ 1733

Query: 657  AGPITEGCFCPEGMTLFSTSAQVCVPTGCPRCLGPHGEPVKVGHTVGMDCQECT------ 710
               + E C C  G  L    +  C+P     C     +P   G        ECT      
Sbjct: 1734 --NLREDCVCKVGTVLHRPHSAQCIPEKECACTDSEDQPRTAGEIWNGGIDECTLYKCLE 1791

Query: 711  ------------------CEAAT---------WTLT------CRPKLCPLP-PACPLPGF 736
                              CE            WT        C   LC    P C     
Sbjct: 1792 NGSIIPIEPDCDEEPTPVCEREAEVVMGIIDKWTCCSKEVCGCDTTLCETSIPTCTNSQK 1851

Query: 737  VPVPAAPQAGQCCPQYSCACNTSRCP--KPVGCPEGARAIPTYQEGACCPVQNCSWTVCS 794
            + V  +P +  CCPQY C C+  +CP      C E    I   QE  CC    C    C+
Sbjct: 1852 LIVGHSPLS--CCPQYKCECDPLKCPSISTPECREDQFMIQVRQEEPCCFSPFCVCESCT 1909

Query: 795  INGTLYQPGAVVSSSLCETCRCELPGGPPSDAFVVSCETQIC-----NTHCPVGFEYQEQ 849
                L   G  ++  L  T  C          +   CE  +C     N    +    +  
Sbjct: 1910 KPVPLCHDGEFLTVDLNSTHFC-------CPQYYCVCEPNLCPMPLLNCAEDMNLVKENV 1962

Query: 850  SGQCCGT---------CVQVACVTNTSKSPAHLFYPGETWSDAGNHCVTHQCEK 894
            SGQCC T          V   C      +  H F      SD G  C+ + CEK
Sbjct: 1963 SGQCCPTWHCECNCENLVMPTCEVGEFTAIDHNFQ-----SDCG--CIQYLCEK 2009



 Score =  112 bits (280), Expect = 2e-24
 Identities = 74/327 (22%), Positives = 127/327 (38%), Gaps = 60/327 (18%)

Query: 748  CCPQYSCACNTSRCPKP-VGCPEGARAIPTYQEGACCPVQNCS-------WTVCSING-- 797
            CCPQY C C  + CP P + C E    +     G CCP  +C           C +    
Sbjct: 1931 CCPQYYCVCEPNLCPMPLLNCAEDMNLVKENVSGQCCPTWHCECNCENLVMPTCEVGEFT 1990

Query: 798  ----------------------------TLYQPG----AVVSSSLCETCRCELPGGPPSD 825
                                        ++  PG      +    C T  C       + 
Sbjct: 1991 AIDHNFQSDCGCIQYLCEKDDVCVFQEVSVLNPGQSMIKYLEEDFCYTIECLEEKDNHTG 2050

Query: 826  AFVVSCETQICNTHCPVGFEYQEQSGQ--CCGTCVQVACVTNTSKSPAHLFYPGETWSDA 883
               ++     C+  C V   Y        CCGTC  V+C  +     + ++  G TW   
Sbjct: 2051 FHTLNFTLVNCSKKCDVHQVYTPSPSDYGCCGTCKNVSCKFHMENGTSVVYAVGSTWH-- 2108

Query: 884  GNHCVTHQCEKHQDGLVVVTTKKACPPLS---CSLDE--ARMSKDGCCRFCPPPPPPYQN 938
              +C T++C K  +G +++     CPP +   C + E   ++  +GCC+ C       + 
Sbjct: 2109 -YNCTTYECVKTDEGAIILNYTMVCPPFNETECKMSEGIVKLYNEGCCKICK------RE 2161

Query: 939  QSTCAVYHRSLIIQQQGCSSSEPVRLAYCRGNCGDSSSMYSLEGNTVEHRCQCCQELRTS 998
            +  C       +I++Q C S  P+ +A C G C  S+++Y++   +    C+CC+E    
Sbjct: 2162 ERICQKVIIKSVIRKQDCMSQSPINVASCDGKC-PSATIYNINIESHLRFCKCCRENGVR 2220

Query: 999  LRNVTLHCT-DGSSRAFSYTEVEECGC 1024
              +V L+C+ +G+   ++  E  +C C
Sbjct: 2221 NLSVPLYCSGNGTEIMYTLQEPIDCTC 2247



 Score = 94.0 bits (232), Expect = 7e-19
 Identities = 93/372 (25%), Positives = 137/372 (36%), Gaps = 50/372 (13%)

Query: 394 VCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVLVDNYFCGAEDGLSCPRSI 453
           +C  WG  H+ TFDG YY F  NC+Y+  +    +   + V V N         SC RSI
Sbjct: 63  ICKTWGQYHFETFDGIYYYFPGNCSYIFAKDCGDLEPRYTVWVHNSPKCLGSVYSCYRSI 122

Query: 454 IL-------------EYHQDRVVLTRKPVHGVMTNEIIFNNKVVSPGFRKNGIVVSRIGV 500
            L             E  ++ + LT     G +  E + +  +V   F  +       G+
Sbjct: 123 SLFFSNQEEIRIYGHEIKKNGISLTLPQTIGQIFIEKLADYILVKTTFGFSLAWDGISGI 182

Query: 501 KMYATIPELGVQVMFSGLIFSVEVP------------FSKFANNTEGQCXXXXXXXTTP- 547
            +  +    G      G    ++               + FAN+   Q         TP 
Sbjct: 183 YLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVLTPS 242

Query: 548 --PAPCLPSPI--------CQLILSKVFEPCHTVIPPLLFYEGCVFDRCHMTDLDVVCSS 597
             P PC             CQ++L   F  CH  I P L+   CV D C   D +  C +
Sbjct: 243 DFPNPCSSGMPAFEAIFFKCQILLQFPFLSCHEYIDPYLYIASCVNDLCKTDDDETYCRA 302

Query: 598 LELYAALCASHDICI-DWRGRTGHMCPFTCPADKVYQPCGPSNPSYCYGNDSASLGALPE 656
              YA  C+     I DWR      C   C    V++ C    P  C   +   LG+   
Sbjct: 303 ATEYARACSHAGYPIQDWRD-DFPACTDKCDDSFVHRDCISCCPPTC-TFEKQCLGSNLH 360

Query: 657 AGPITEGCFCPEGMTLFSTSAQVCVP-TGCPRCLGPHGEPVKVGHTVGMDCQECTCEAAT 715
                +GC+CP+G+ + + +   C+    CP   G HG    VG  +  +C EC C    
Sbjct: 361 C---LDGCYCPDGLVMDNGT---CISLENCP--CGFHGLAYSVGSKIEQECTECVCVGGV 412

Query: 716 WTLTCRPKLCPL 727
           W   C  + CP+
Sbjct: 413 W--NCTEQDCPV 422



 Score = 92.0 bits (227), Expect = 3e-18
 Identities = 120/468 (25%), Positives = 167/468 (35%), Gaps = 79/468 (16%)

Query: 386 CHHYQCQCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVLVDNYFCGAED 445
           C    C   CS  GD H+ TFDG +Y+F+  C Y+LV+        F + +    C    
Sbjct: 415 CTEQDCPVQCSVVGDSHFTTFDGRHYSFIGMCQYILVKGTGK--DKFTITLQKAPCEQNL 472

Query: 446 GLSCPRSIILEYHQDRVVLTRKPVHGVMTNEIIFNNKVVSPGFRKNGIVV---------- 495
           GL C +SI L    D      K V      +I+ +    + GF  NGIV           
Sbjct: 473 GLVCLQSITLILEDD----FNKQVTLGRGGQILTSP---NQGFNLNGIVEIQTLSSLFIL 525

Query: 496 --SRIGVKMYATIP---------------ELGVQVMFSGLIFSVEVPFSKFANNT----- 533
             +  G+K+   I                 LG+   F+G I    +  S     T     
Sbjct: 526 LKTTFGLKILFAIDGERIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEGTPQLHA 585

Query: 534 -----EGQCXXXXXXXTTPPAPCLPSPI-----CQLILSKVFEPCHTVIPPLLFYEGCVF 583
                   C          P       I     C +I  ++F PCH  I P L+Y+ C  
Sbjct: 586 NAWRVSSTCFAPVHVPVVDPCNINQQNIGYAAHCDVIHQELFAPCHIYISPGLYYQLCRH 645

Query: 584 DRCHMTDLDVVCSSLELYAALCASHDICIDWRGRTGHMCPFTCPADKVYQPCGPSNPSYC 643
           D C       +C++L  YA LC  H + ID+R +    C   C    +Y  C     S+C
Sbjct: 646 DACKCGS-SCLCNALAHYAYLCGQHGVPIDFRTQIS-FCAVVCQKGMLYHHCS----SFC 699

Query: 644 YGNDSASLGALPE--AGPITEGCFCPEGMTLFSTSAQVCVPTGCPRCLGPHGEPVKVGHT 701
             +   SL + PE  +    EGC CPEG   +  +   CVP    RC    G   + G  
Sbjct: 700 L-HSCISLSS-PEQCSDDCAEGCNCPEG-KFYEDTLNFCVPIFHCRC-HYRGSVYQPGEL 755

Query: 702 VGMDCQECTCEAATWTLTCRPKLCP-LPPACP-----LPGFVPVPAAPQAGQCCPQYSCA 755
           +      C C  +  T+ C     P     CP          P P  P  G  C + +CA
Sbjct: 756 IPTPSGLCQC--SNGTVKCDELATPSAVHICPEGKEYFDCRFPDPELPAGGVNC-ETTCA 812

Query: 756 --CNTSRCPKPVGCPEGARAIPTYQEGAC-CPVQNCSWTVCSINGTLY 800
                  C     C  G    P    G C   + NC++  C    T+Y
Sbjct: 813 NLAMNFTCTPSSPCISGCVCAP----GVCRRGMFNCTYYPCPAVCTIY 856



 Score = 68.6 bits (166), Expect = 3e-11
 Identities = 71/312 (22%), Positives = 109/312 (34%), Gaps = 62/312 (19%)

Query: 386  CHHYQCQCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVLVDNYFCGAED 445
            C +Y C  VC+ +GD HY +FDG  Y ++ +C   L++          V+  N  C   D
Sbjct: 844  CTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLIKSADD--SDISVIAQNKKCFDND 901

Query: 446  GLSCPRSIILEYHQDRVVLTRKPVHGVMTNEIIFNNKVVSPGFRKNGIVVSRIGVKMYAT 505
             + C +S+++      + L   P     +   + N         K+   + + G  +   
Sbjct: 902  -IVCSKSVLISVGDTEIYLNDTPYKQKQSGFFLEN---------KSTYQLWKAGYYIVVY 951

Query: 506  IPELGVQVMF------------------SGLIFSVEVPFSK---FANNTE---------- 534
             PE  + +++                  SGL  + +   S     +NN E          
Sbjct: 952  FPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDS 1011

Query: 535  ---GQCXXXXXXXTTPPAPCLPSPI----CQLILSKVFEPCHTVIPPLLFYEGCVFDRCH 587
               GQC           A     P     C ++ S +F  C  VI    F + C  D C+
Sbjct: 1012 WALGQCESPDETIKPCEAHQNKFPYAKKECSILYSDIFASCRNVIDVTSFAKNCHEDTCN 1071

Query: 588  MT---DLDVVCSSLELYAALCASHDICIDWRGRTGHMCPFTCPADKVYQPCGPSNPSY-- 642
                 D + +C+S+  YA  C    I I WR  T       C  D  Y   G     Y  
Sbjct: 1072 CNLGGDCECLCTSIAAYAYKCCQEGISIHWRSST------VCSLDCEYYNEGLGEGPYML 1125

Query: 643  -CYGNDSASLGA 653
              YG     LGA
Sbjct: 1126 ASYGQSGLVLGA 1137



 Score = 32.7 bits (73), Expect = 1.9
 Identities = 25/86 (29%), Positives = 34/86 (39%), Gaps = 11/86 (12%)

Query: 761 CPKPVGCPEGARAIPTYQEGACCPVQNCSWTVCSINGTLYQPGAVVSSSLCETCRCELPG 820
           C +   CPEG     T     C P+ +C    C   G++YQPG ++ +     C+C   G
Sbjct: 716 CAEGCNCPEGKFYEDTLN--FCVPIFHCR---CHYRGSVYQPGELIPTP-SGLCQCS-NG 768

Query: 821 GPPSDAFVVSCETQICNTHCPVGFEY 846
               D         I    CP G EY
Sbjct: 769 TVKCDELATPSAVHI----CPEGKEY 790


>gi|239750386 PREDICTED: chromosome 12 open reading frame 64 [Homo
            sapiens]
          Length = 2250

 Score =  114 bits (285), Expect = 5e-25
 Identities = 163/714 (22%), Positives = 233/714 (32%), Gaps = 167/714 (23%)

Query: 303  TTLPPAPATSPSISTSE--------------PVTELGCPNAVPPRKKGETWATPNCSEAT 348
            T +PPA  T P  +  E              P T L C     P+K    +   +CS+  
Sbjct: 1341 TLMPPAKPTVPMFTVWEMITPSDITVFDMLTPTTGLECE----PQKFDPVY---DCSQYI 1393

Query: 349  CEGNN-VISLRPRTCPR-VEKPTCANGYPAVKVADQDGCCHHYQCQCVCSGWGDPHYITF 406
            C      +      CP+ VE P C      V+V + D CC  ++C C CS   +   ITF
Sbjct: 1394 CLNMEWQLYNWSLNCPKDVEMPDCGFRGRPVQV-NSDICCPEWECPCRCSMLSELSIITF 1452

Query: 407  DGTYYTFLDNCTYVLVQQIVP---VYGHFRVLVDNYFCGAEDGLSCPRSIILEYHQDRVV 463
            DG         +Y+LV+  +P   +  H      N          C + + +     +++
Sbjct: 1453 DGNNAALYSMASYILVR--IPGEIIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKII 1510

Query: 464  LTRKPVHGVMTNEIIFNNKVVSPGFRKNGIVVSRIGVKMYATIPELGVQVMFSGLIFSVE 523
            + R      +  ++  ++ VV   F    + +   G  MY      G+ + +S L   ++
Sbjct: 1511 VNR------LARKVEVDSIVVPLPFSSQELSIEDSG-SMYVITTPAGLIIKWSHLTGIID 1563

Query: 524  VPFS---KFANNTEGQCXXXXXXXTT---------------------------------- 546
            + F      ++ TEG C                                           
Sbjct: 1564 IHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTMR 1623

Query: 547  -PPAPCLPSPICQ---LILSKVFEPCHTVIPPLLFYEGCVFDRCHMTDLDVVCSSLELYA 602
             P   C      Q   L+  ++F PCH  + P  F E    +  +  + +  C +L  Y 
Sbjct: 1624 RPVRNCTEHDCSQCIDLLNRRIFIPCHDKVSPEDFCEKMWINYTYFWNYE--CDALSAYV 1681

Query: 603  ALCASHDICIDWRGRTGHMCPFTCPADKVYQPC-GPSNPSYC-----YGNDSASLGALPE 656
            ALC   DICI W  RT   C  +CP  K YQPC  P     C     YG+ S        
Sbjct: 1682 ALCNKFDICIQW--RTPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSCL------ 1733

Query: 657  AGPITEGCFCPEGMTLFSTSAQVCVPTGCPRCLGPHGEPVKVGHTVGMDCQECT------ 710
               + E C C  G  L    +  C+P     C     +P   G        ECT      
Sbjct: 1734 --NLREDCVCKVGTILHRPHSAQCIPEKECACTDSEDQPRTAGEIWNGGIDECTLYKCLE 1791

Query: 711  ------------------CEAAT---------WTLT------CRPKLCPLP-PACPLPGF 736
                              CE            WT        C   LC    P C     
Sbjct: 1792 NGSIIPIEPDCDEEPTPVCEREAEVVMGIIDKWTCCSKEVCGCDTTLCETSIPTCTNSQK 1851

Query: 737  VPVPAAPQAGQCCPQYSCACNTSRCP--KPVGCPEGARAIPTYQEGACCPVQNCSWTVCS 794
            + V  +P +  CCPQY C C+  +CP      C E    I   QE  CC    C    C+
Sbjct: 1852 LIVGHSPLS--CCPQYKCECDPLKCPSISTPECREDQFMIQVRQEEPCCFSPFCVCESCT 1909

Query: 795  INGTLYQPGAVVSSSLCETCRCELPGGPPSDAFVVSCETQIC-----NTHCPVGFEYQEQ 849
                L   G  ++  L  T  C          +   CE  +C     N    +    +  
Sbjct: 1910 KPVPLCHDGEFLTVDLNSTHFC-------CPQYYCVCEPNLCPMPLLNCAEDMNLVKENV 1962

Query: 850  SGQCCGT---------CVQVACVTNTSKSPAHLFYPGETWSDAGNHCVTHQCEK 894
            SGQCC T          V   C      +  H F      SD G  C+ + CEK
Sbjct: 1963 SGQCCPTWHCECNCENLVMPTCEVGEFTAIDHNFQ-----SDCG--CIQYLCEK 2009



 Score =  112 bits (281), Expect = 1e-24
 Identities = 74/327 (22%), Positives = 128/327 (39%), Gaps = 60/327 (18%)

Query: 748  CCPQYSCACNTSRCPKP-VGCPEGARAIPTYQEGACCPVQNCS-------WTVCSING-- 797
            CCPQY C C  + CP P + C E    +     G CCP  +C           C +    
Sbjct: 1931 CCPQYYCVCEPNLCPMPLLNCAEDMNLVKENVSGQCCPTWHCECNCENLVMPTCEVGEFT 1990

Query: 798  ----------------------------TLYQPG----AVVSSSLCETCRCELPGGPPSD 825
                                        ++  PG      +    C T  C       + 
Sbjct: 1991 AIDHNFQSDCGCIQYLCEKDDVCVFQEVSVLNPGQSMIKYLEEDFCYTIECLEEKDNHTG 2050

Query: 826  AFVVSCETQICNTHCPVGFEYQEQSGQ--CCGTCVQVACVTNTSKSPAHLFYPGETWSDA 883
               ++     C+  C V   Y        CCGTC  V+C  +     + ++  G TW   
Sbjct: 2051 FHTLNFTLVNCSKKCDVHQVYTPSPSDYGCCGTCKNVSCKFHMENGTSVVYAVGSTWH-- 2108

Query: 884  GNHCVTHQCEKHQDGLVVVTTKKACPPLS---CSLDE--ARMSKDGCCRFCPPPPPPYQN 938
              +C T++C K  +G +++     CPP +   C ++E   ++  +GCC+ C       + 
Sbjct: 2109 -YNCTTYECVKTDEGAIILNYTMVCPPFNETECKMNEGIVKLYNEGCCKICK------RE 2161

Query: 939  QSTCAVYHRSLIIQQQGCSSSEPVRLAYCRGNCGDSSSMYSLEGNTVEHRCQCCQELRTS 998
            +  C       +I++Q C S  P+ +A C G C  S+++Y++   +    C+CC+E    
Sbjct: 2162 ERICQKVIIKSVIRKQDCMSQSPINVASCDGKC-PSATIYNINIESHLRFCKCCRENGVR 2220

Query: 999  LRNVTLHCT-DGSSRAFSYTEVEECGC 1024
              +V L+C+ +G+   ++  E  +C C
Sbjct: 2221 NLSVPLYCSGNGTEIMYTLQEPIDCTC 2247



 Score = 94.0 bits (232), Expect = 7e-19
 Identities = 93/372 (25%), Positives = 137/372 (36%), Gaps = 50/372 (13%)

Query: 394 VCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVLVDNYFCGAEDGLSCPRSI 453
           +C  WG  H+ TFDG YY F  NC+Y+  +    +   + V V N         SC RSI
Sbjct: 63  ICKTWGQYHFETFDGIYYYFPGNCSYIFAKDCGDLEPRYTVWVHNSPKCLGSVYSCYRSI 122

Query: 454 IL-------------EYHQDRVVLTRKPVHGVMTNEIIFNNKVVSPGFRKNGIVVSRIGV 500
            L             E  ++ + LT     G +  E + +  +V   F  +       G+
Sbjct: 123 SLFFSNQEEIRIYGHEIKKNGISLTLPQTIGQIFIEKLADYILVKTTFGFSLAWDGISGI 182

Query: 501 KMYATIPELGVQVMFSGLIFSVEVP------------FSKFANNTEGQCXXXXXXXTTP- 547
            +  +    G      G    ++               + FAN+   Q         TP 
Sbjct: 183 YLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVLTPS 242

Query: 548 --PAPCLPSPI--------CQLILSKVFEPCHTVIPPLLFYEGCVFDRCHMTDLDVVCSS 597
             P PC             CQ++L   F  CH  I P L+   CV D C   D +  C +
Sbjct: 243 DFPNPCSSGMPAFEAIFFKCQILLQFPFLSCHEYIDPYLYIASCVNDLCKTDDDETYCRA 302

Query: 598 LELYAALCASHDICI-DWRGRTGHMCPFTCPADKVYQPCGPSNPSYCYGNDSASLGALPE 656
              YA  C+     I DWR      C   C    V++ C    P  C   +   LG+   
Sbjct: 303 ATEYARACSHAGYPIQDWRD-DFPACTDKCDDSFVHRDCISCCPPTC-TFEKQCLGSNLH 360

Query: 657 AGPITEGCFCPEGMTLFSTSAQVCVP-TGCPRCLGPHGEPVKVGHTVGMDCQECTCEAAT 715
                +GC+CP+G+ + + +   C+    CP   G HG    VG  +  +C EC C    
Sbjct: 361 C---LDGCYCPDGLVMDNGT---CISLENCP--CGFHGLAYSVGSKIEQECTECVCVGGV 412

Query: 716 WTLTCRPKLCPL 727
           W   C  + CP+
Sbjct: 413 W--NCTEQDCPV 422



 Score = 92.0 bits (227), Expect = 3e-18
 Identities = 120/468 (25%), Positives = 167/468 (35%), Gaps = 79/468 (16%)

Query: 386 CHHYQCQCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVLVDNYFCGAED 445
           C    C   CS  GD H+ TFDG +Y+F+  C Y+LV+        F + +    C    
Sbjct: 415 CTEQDCPVQCSVVGDSHFTTFDGRHYSFIGMCQYILVKGTGK--DKFTITLQKAPCEQNL 472

Query: 446 GLSCPRSIILEYHQDRVVLTRKPVHGVMTNEIIFNNKVVSPGFRKNGIVV---------- 495
           GL C +SI L    D      K V      +I+ +    + GF  NGIV           
Sbjct: 473 GLVCLQSITLILEDD----FNKQVTLGRGGQILTSP---NQGFNLNGIVEIQTLSSLFIL 525

Query: 496 --SRIGVKMYATIP---------------ELGVQVMFSGLIFSVEVPFSKFANNT----- 533
             +  G+K+   I                 LG+   F+G I    +  S     T     
Sbjct: 526 LKTTFGLKILFAIDGERIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEGTPQLHA 585

Query: 534 -----EGQCXXXXXXXTTPPAPCLPSPI-----CQLILSKVFEPCHTVIPPLLFYEGCVF 583
                   C          P       I     C +I  ++F PCH  I P L+Y+ C  
Sbjct: 586 NAWRVSSTCFAPVHVPVVDPCNINQQNIGYAAHCDVIHQELFAPCHIYISPGLYYQLCRH 645

Query: 584 DRCHMTDLDVVCSSLELYAALCASHDICIDWRGRTGHMCPFTCPADKVYQPCGPSNPSYC 643
           D C       +C++L  YA LC  H + ID+R +    C   C    +Y  C     S+C
Sbjct: 646 DACKCGS-SCLCNALAHYAYLCGQHGVPIDFRTQIS-FCAVVCQKGMLYHHCS----SFC 699

Query: 644 YGNDSASLGALPE--AGPITEGCFCPEGMTLFSTSAQVCVPTGCPRCLGPHGEPVKVGHT 701
             +   SL + PE  +    EGC CPEG   +  +   CVP    RC    G   + G  
Sbjct: 700 L-HSCISLSS-PEQCSDDCAEGCNCPEG-KFYEDTLNFCVPIFHCRC-HYRGSVYQPGEL 755

Query: 702 VGMDCQECTCEAATWTLTCRPKLCP-LPPACP-----LPGFVPVPAAPQAGQCCPQYSCA 755
           +      C C  +  T+ C     P     CP          P P  P  G  C + +CA
Sbjct: 756 IPTPSGLCQC--SNGTVKCDELATPSAVHICPEGKEYFDCRFPDPELPAGGVNC-ETTCA 812

Query: 756 --CNTSRCPKPVGCPEGARAIPTYQEGAC-CPVQNCSWTVCSINGTLY 800
                  C     C  G    P    G C   + NC++  C    T+Y
Sbjct: 813 NLAMNFTCTPSSPCISGCVCAP----GVCRRGMFNCTYYPCPAVCTIY 856



 Score = 68.6 bits (166), Expect = 3e-11
 Identities = 71/312 (22%), Positives = 109/312 (34%), Gaps = 62/312 (19%)

Query: 386  CHHYQCQCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVLVDNYFCGAED 445
            C +Y C  VC+ +GD HY +FDG  Y ++ +C   L++          V+  N  C   D
Sbjct: 844  CTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLIKSADD--SDISVIAQNKKCFDND 901

Query: 446  GLSCPRSIILEYHQDRVVLTRKPVHGVMTNEIIFNNKVVSPGFRKNGIVVSRIGVKMYAT 505
             + C +S+++      + L   P     +   + N         K+   + + G  +   
Sbjct: 902  -IVCSKSVLISVGDTEIYLNDTPYKQKQSGFFLEN---------KSTYQLWKAGYYIVVY 951

Query: 506  IPELGVQVMF------------------SGLIFSVEVPFSK---FANNTE---------- 534
             PE  + +++                  SGL  + +   S     +NN E          
Sbjct: 952  FPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDS 1011

Query: 535  ---GQCXXXXXXXTTPPAPCLPSPI----CQLILSKVFEPCHTVIPPLLFYEGCVFDRCH 587
               GQC           A     P     C ++ S +F  C  VI    F + C  D C+
Sbjct: 1012 WALGQCESPDETIKPCEAHQNKFPYAKKECSILYSDIFASCRNVIDVTSFAKNCHEDTCN 1071

Query: 588  MT---DLDVVCSSLELYAALCASHDICIDWRGRTGHMCPFTCPADKVYQPCGPSNPSY-- 642
                 D + +C+S+  YA  C    I I WR  T       C  D  Y   G     Y  
Sbjct: 1072 CNLGGDCECLCTSIAAYAYKCCQEGISIHWRSST------VCSLDCEYYNEGLGEGPYML 1125

Query: 643  -CYGNDSASLGA 653
              YG     LGA
Sbjct: 1126 ASYGQSGLVLGA 1137



 Score = 32.7 bits (73), Expect = 1.9
 Identities = 25/86 (29%), Positives = 34/86 (39%), Gaps = 11/86 (12%)

Query: 761 CPKPVGCPEGARAIPTYQEGACCPVQNCSWTVCSINGTLYQPGAVVSSSLCETCRCELPG 820
           C +   CPEG     T     C P+ +C    C   G++YQPG ++ +     C+C   G
Sbjct: 716 CAEGCNCPEGKFYEDTLN--FCVPIFHCR---CHYRGSVYQPGELIPTP-SGLCQCS-NG 768

Query: 821 GPPSDAFVVSCETQICNTHCPVGFEY 846
               D         I    CP G EY
Sbjct: 769 TVKCDELATPSAVHI----CPEGKEY 790


>gi|239744688 PREDICTED: hypothetical protein LOC283310 [Homo sapiens]
          Length = 2250

 Score =  114 bits (284), Expect = 6e-25
 Identities = 162/714 (22%), Positives = 233/714 (32%), Gaps = 167/714 (23%)

Query: 303  TTLPPAPATSPSISTSE--------------PVTELGCPNAVPPRKKGETWATPNCSEAT 348
            T +PPA  T P  +  E              P T L C     P+K    +   +CS+  
Sbjct: 1341 TLMPPAKPTVPMFTVWEMITPSDITVFDMLTPTTGLECE----PQKFDPVY---DCSQYI 1393

Query: 349  CEGNN-VISLRPRTCPR-VEKPTCANGYPAVKVADQDGCCHHYQCQCVCSGWGDPHYITF 406
            C      +      CP+ VE P C      V+V + D CC  ++C C CS   +   ITF
Sbjct: 1394 CLNMEWQLYNWSLNCPKDVEMPDCGFRGRPVQV-NSDICCPEWECPCRCSMLSELSIITF 1452

Query: 407  DGTYYTFLDNCTYVLVQQIVP---VYGHFRVLVDNYFCGAEDGLSCPRSIILEYHQDRVV 463
            DG         +Y+LV+  +P   +  H      N          C + + +     +++
Sbjct: 1453 DGNNAALYSMASYILVR--IPGEIIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKII 1510

Query: 464  LTRKPVHGVMTNEIIFNNKVVSPGFRKNGIVVSRIGVKMYATIPELGVQVMFSGLIFSVE 523
            + R      +  ++  ++ VV   F    + +   G  MY      G+ + +S L   ++
Sbjct: 1511 VNR------LARKVEVDSIVVPLPFSSQELSIEDSG-SMYVITTPAGLIIKWSHLTGIID 1563

Query: 524  VPFS---KFANNTEGQCXXXXXXXTT---------------------------------- 546
            + F      ++ TEG C                                           
Sbjct: 1564 IHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTMR 1623

Query: 547  -PPAPCLPSPICQ---LILSKVFEPCHTVIPPLLFYEGCVFDRCHMTDLDVVCSSLELYA 602
             P   C      Q   L+  ++F PCH  + P  F E    +  +  + +  C +L  Y 
Sbjct: 1624 RPVRNCTEHDCSQCIDLLNRRIFIPCHDKVSPEDFCEKMWINYTYFWNYE--CDALSAYV 1681

Query: 603  ALCASHDICIDWRGRTGHMCPFTCPADKVYQPC-GPSNPSYC-----YGNDSASLGALPE 656
            ALC   DICI W  RT   C  +CP  K YQPC  P     C     YG+ S        
Sbjct: 1682 ALCNKFDICIQW--RTPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSCL------ 1733

Query: 657  AGPITEGCFCPEGMTLFSTSAQVCVPTGCPRCLGPHGEPVKVGHTVGMDCQECT------ 710
               + E C C  G  L    +  C+P     C     +P   G        ECT      
Sbjct: 1734 --NLREDCVCKVGTILHRPHSAQCIPEKECACTDSEDQPRTAGEIWNGGIDECTLYKCLE 1791

Query: 711  ------------------CEAAT---------WTLT------CRPKLCPLP-PACPLPGF 736
                              CE            WT        C   LC    P C     
Sbjct: 1792 NGSIIPIEPDCDEEPTPVCEREAEVVMGIIDKWTCCSKEVCGCDTTLCETSIPTCTNSQK 1851

Query: 737  VPVPAAPQAGQCCPQYSCACNTSRCP--KPVGCPEGARAIPTYQEGACCPVQNCSWTVCS 794
            + V  +P +  CCPQY C C+  +CP      C E    I   QE  CC    C    C+
Sbjct: 1852 LIVGHSPLS--CCPQYKCECDPLKCPSISTPECREDQFMIQVRQEEPCCFSPFCVCESCT 1909

Query: 795  INGTLYQPGAVVSSSLCETCRCELPGGPPSDAFVVSCETQIC-----NTHCPVGFEYQEQ 849
                L   G  ++  L  T  C          +   CE  +C     N    +    +  
Sbjct: 1910 KPVPLCHDGEFLTVDLNSTHFC-------CPQYYCVCEPNLCPMPLLNCAEDMNLVKENV 1962

Query: 850  SGQCCGT---------CVQVACVTNTSKSPAHLFYPGETWSDAGNHCVTHQCEK 894
            SGQCC T          +   C      +  H F      SD G  C+ + CEK
Sbjct: 1963 SGQCCPTWHCECNCENLIMPTCEVGEFTAIDHNFQ-----SDCG--CIQYLCEK 2009



 Score =  111 bits (277), Expect = 4e-24
 Identities = 74/327 (22%), Positives = 129/327 (39%), Gaps = 60/327 (18%)

Query: 748  CCPQYSCACNTSRCPKPV-GCPEGARAIPTYQEGACCPVQNCSWTVCSINGTLYQPG--A 804
            CCPQY C C  + CP P+  C E    +     G CCP  +C     ++     + G   
Sbjct: 1931 CCPQYYCVCEPNLCPMPLLNCAEDMNLVKENVSGQCCPTWHCECNCENLIMPTCEVGEFT 1990

Query: 805  VVSSSLCETCRC--------------ELPGGPPSDAFVVSCETQIC-------------- 836
             +  +    C C              E+    P  + +   E   C              
Sbjct: 1991 AIDHNFQSDCGCIQYLCEKDDVCVFQEVSVLNPGQSMIKYLEEDFCYAIECLEEKDNHTG 2050

Query: 837  -----------NTHCPVGFEYQEQSGQ--CCGTCVQVACVTNTSKSPAHLFYPGETWSDA 883
                       +  C V   Y        CCGTC  V+C  +     + ++  G TW   
Sbjct: 2051 FHTLNFTLVNCSKKCDVHQVYTPSPSDYGCCGTCKNVSCKFHMENGTSVVYAVGSTWH-- 2108

Query: 884  GNHCVTHQCEKHQDGLVVVTTKKACPPLS---CSLDE--ARMSKDGCCRFCPPPPPPYQN 938
              +C T++C K  +G +++     CPP +   C ++E   ++  +GCC+ C       + 
Sbjct: 2109 -YNCTTYECVKTDEGAIILNYTMVCPPFNETECKMNEGIVKLYNEGCCKICK------RE 2161

Query: 939  QSTCAVYHRSLIIQQQGCSSSEPVRLAYCRGNCGDSSSMYSLEGNTVEHRCQCCQELRTS 998
            +  C       +I++Q C S  P+ +A C G C  S+++Y++   +    C+CC+E    
Sbjct: 2162 ERICQKVIIKSVIRKQDCMSQSPINVASCDGKC-PSATIYNINIESHLRFCKCCRENGVR 2220

Query: 999  LRNVTLHCT-DGSSRAFSYTEVEECGC 1024
              +V L+C+ +G+   ++  E  +C C
Sbjct: 2221 NLSVPLYCSGNGTEIMYTLQEPIDCTC 2247



 Score = 94.0 bits (232), Expect = 7e-19
 Identities = 93/372 (25%), Positives = 137/372 (36%), Gaps = 50/372 (13%)

Query: 394 VCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVLVDNYFCGAEDGLSCPRSI 453
           +C  WG  H+ TFDG YY F  NC+Y+  +    +   + V V N         SC RSI
Sbjct: 63  ICKTWGQYHFETFDGIYYYFPGNCSYIFAKDCGDLEPRYTVWVHNSPKCLGSVYSCYRSI 122

Query: 454 IL-------------EYHQDRVVLTRKPVHGVMTNEIIFNNKVVSPGFRKNGIVVSRIGV 500
            L             E  ++ + LT     G +  E + +  +V   F  +       G+
Sbjct: 123 SLFFSNQEEIRIYGHEIKKNGISLTLPQTIGQIFIEKLADYILVKTTFGFSLAWDGISGI 182

Query: 501 KMYATIPELGVQVMFSGLIFSVEVP------------FSKFANNTEGQCXXXXXXXTTP- 547
            +  +    G      G    ++               + FAN+   Q         TP 
Sbjct: 183 YLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVLTPS 242

Query: 548 --PAPCLPSPI--------CQLILSKVFEPCHTVIPPLLFYEGCVFDRCHMTDLDVVCSS 597
             P PC             CQ++L   F  CH  I P L+   CV D C   D +  C +
Sbjct: 243 DFPNPCSSGMPAFEAIFFKCQILLQFPFLSCHEYIDPYLYIASCVNDLCKTDDDETYCRA 302

Query: 598 LELYAALCASHDICI-DWRGRTGHMCPFTCPADKVYQPCGPSNPSYCYGNDSASLGALPE 656
              YA  C+     I DWR      C   C    V++ C    P  C   +   LG+   
Sbjct: 303 ATEYARACSHAGYPIQDWRD-DFPACTDKCDDSFVHRDCISCCPPTC-TFEKQCLGSNLH 360

Query: 657 AGPITEGCFCPEGMTLFSTSAQVCVP-TGCPRCLGPHGEPVKVGHTVGMDCQECTCEAAT 715
                +GC+CP+G+ + + +   C+    CP   G HG    VG  +  +C EC C    
Sbjct: 361 C---LDGCYCPDGLVMDNGT---CISLENCP--CGFHGLAYSVGSKIEQECTECVCVGGV 412

Query: 716 WTLTCRPKLCPL 727
           W   C  + CP+
Sbjct: 413 W--NCTEQDCPV 422



 Score = 92.0 bits (227), Expect = 3e-18
 Identities = 120/468 (25%), Positives = 167/468 (35%), Gaps = 79/468 (16%)

Query: 386 CHHYQCQCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVLVDNYFCGAED 445
           C    C   CS  GD H+ TFDG +Y+F+  C Y+LV+        F + +    C    
Sbjct: 415 CTEQDCPVQCSVVGDSHFTTFDGRHYSFIGMCQYILVKGTGK--DKFTITLQKAPCEQNL 472

Query: 446 GLSCPRSIILEYHQDRVVLTRKPVHGVMTNEIIFNNKVVSPGFRKNGIVV---------- 495
           GL C +SI L    D      K V      +I+ +    + GF  NGIV           
Sbjct: 473 GLVCLQSITLILEDD----FNKQVTLGRGGQILTSP---NQGFNLNGIVEIQTLSSLFIL 525

Query: 496 --SRIGVKMYATIP---------------ELGVQVMFSGLIFSVEVPFSKFANNT----- 533
             +  G+K+   I                 LG+   F+G I    +  S     T     
Sbjct: 526 LKTTFGLKILFAIDGERIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEGTPQLHA 585

Query: 534 -----EGQCXXXXXXXTTPPAPCLPSPI-----CQLILSKVFEPCHTVIPPLLFYEGCVF 583
                   C          P       I     C +I  ++F PCH  I P L+Y+ C  
Sbjct: 586 NAWRVSSTCFAPVHVPVVDPCNINQQNIGYAAHCDVIHQELFAPCHIYISPGLYYQLCRH 645

Query: 584 DRCHMTDLDVVCSSLELYAALCASHDICIDWRGRTGHMCPFTCPADKVYQPCGPSNPSYC 643
           D C       +C++L  YA LC  H + ID+R +    C   C    +Y  C     S+C
Sbjct: 646 DACKCGS-SCLCNALAHYAYLCGQHGVPIDFRTQIS-FCAVVCQKGMLYHHCS----SFC 699

Query: 644 YGNDSASLGALPE--AGPITEGCFCPEGMTLFSTSAQVCVPTGCPRCLGPHGEPVKVGHT 701
             +   SL + PE  +    EGC CPEG   +  +   CVP    RC    G   + G  
Sbjct: 700 L-HSCISLSS-PEQCSDDCAEGCNCPEG-KFYEDTLNFCVPIFHCRC-HYRGSVYQPGEL 755

Query: 702 VGMDCQECTCEAATWTLTCRPKLCP-LPPACP-----LPGFVPVPAAPQAGQCCPQYSCA 755
           +      C C  +  T+ C     P     CP          P P  P  G  C + +CA
Sbjct: 756 IPTPSGLCQC--SNGTVKCDELATPSAVHICPEGKEYFDCRFPDPELPAGGVNC-ETTCA 812

Query: 756 --CNTSRCPKPVGCPEGARAIPTYQEGAC-CPVQNCSWTVCSINGTLY 800
                  C     C  G    P    G C   + NC++  C    T+Y
Sbjct: 813 NLAMNFTCTPSSPCISGCVCAP----GVCRRGMFNCTYYPCPAVCTIY 856



 Score = 68.6 bits (166), Expect = 3e-11
 Identities = 71/312 (22%), Positives = 109/312 (34%), Gaps = 62/312 (19%)

Query: 386  CHHYQCQCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVLVDNYFCGAED 445
            C +Y C  VC+ +GD HY +FDG  Y ++ +C   L++          V+  N  C   D
Sbjct: 844  CTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLIKSADD--SDISVIAQNKKCFDND 901

Query: 446  GLSCPRSIILEYHQDRVVLTRKPVHGVMTNEIIFNNKVVSPGFRKNGIVVSRIGVKMYAT 505
             + C +S+++      + L   P     +   + N         K+   + + G  +   
Sbjct: 902  -IVCSKSVLISVGDTEIYLNDTPYKQKQSGFFLEN---------KSTYQLWKAGYYIVVY 951

Query: 506  IPELGVQVMF------------------SGLIFSVEVPFSK---FANNTE---------- 534
             PE  + +++                  SGL  + +   S     +NN E          
Sbjct: 952  FPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDS 1011

Query: 535  ---GQCXXXXXXXTTPPAPCLPSPI----CQLILSKVFEPCHTVIPPLLFYEGCVFDRCH 587
               GQC           A     P     C ++ S +F  C  VI    F + C  D C+
Sbjct: 1012 WALGQCESPDETIKPCEAHQNKFPYAKKECSILYSDIFASCRNVIDVTSFAKNCHEDTCN 1071

Query: 588  MT---DLDVVCSSLELYAALCASHDICIDWRGRTGHMCPFTCPADKVYQPCGPSNPSY-- 642
                 D + +C+S+  YA  C    I I WR  T       C  D  Y   G     Y  
Sbjct: 1072 CNLGGDCECLCTSIAAYAYKCCQEGISIHWRSST------VCSLDCEYYNEGLGEGPYML 1125

Query: 643  -CYGNDSASLGA 653
              YG     LGA
Sbjct: 1126 ASYGQSGLVLGA 1137



 Score = 32.7 bits (73), Expect = 1.9
 Identities = 25/86 (29%), Positives = 34/86 (39%), Gaps = 11/86 (12%)

Query: 761 CPKPVGCPEGARAIPTYQEGACCPVQNCSWTVCSINGTLYQPGAVVSSSLCETCRCELPG 820
           C +   CPEG     T     C P+ +C    C   G++YQPG ++ +     C+C   G
Sbjct: 716 CAEGCNCPEGKFYEDTLN--FCVPIFHCR---CHYRGSVYQPGELIPTP-SGLCQCS-NG 768

Query: 821 GPPSDAFVVSCETQICNTHCPVGFEY 846
               D         I    CP G EY
Sbjct: 769 TVKCDELATPSAVHI----CPEGKEY 790


>gi|239757286 PREDICTED: similar to Fc fragment of IgG binding
           protein [Homo sapiens]
          Length = 1472

 Score =  108 bits (270), Expect = 3e-23
 Identities = 130/485 (26%), Positives = 187/485 (38%), Gaps = 101/485 (20%)

Query: 311 TSPSISTSEPVTELGCPNAVPPRKKGETWATPNCSEATCEGNNVISLRPRTCPRVEKPTC 370
           T+  I T+E  T LG          G   A    + A C G  V+S    +C  ++   C
Sbjct: 461 TADMIHTAEATTNLGLLTF------GLAKAIGYATAADC-GRTVLSPVEPSCEGMQ---C 510

Query: 371 ANGYPAVKVADQDGCCHHYQCQCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQ-----QI 425
           A G     V  + GC    +   VC   GDPHY TFDG  Y  +  C+Y +V+       
Sbjct: 511 AAGQRCQVVGGKAGCVA--ESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDT 568

Query: 426 VPVYGHFRVLVDNYFCGAEDGLSCPRSIILEYHQDRVVLTRKPVHGVMTNEIIFNNKVVS 485
           +P    F V   N   G+   +S    + +  +   V LTR  V  V+ +    N +   
Sbjct: 569 LPA---FSVEAKNEHRGSR-RVSYVGLVTVRAYSHSVSLTRGEVGFVLVD----NQRSRL 620

Query: 486 PGFRKNGIVVSRIGVKMYATIPELGVQVMFSGLI--------FSVEVPFSKFANNTEGQC 537
           P      + +S   +++Y + P   V+++F GL+         ++ +P ++F +   G C
Sbjct: 621 P------VSLSEGRLRVYQSGPRAVVELVF-GLVVTYDWDCQLALSLP-ARFQDQVCGLC 672

Query: 538 XXXXXXXT----TPPAPCLPSPI------------------CQL---------------- 559
                       TP     P  +                  CQ                 
Sbjct: 673 GNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGD 732

Query: 560 ----ILSKVFEP---CHTVIPPLLFYEGCVFDRCHMTDLDV-VCSSLELYAALCASHDIC 611
               +L+K+  P   CH  + P  F E CV+D C +    + +C  L  YA  C    I 
Sbjct: 733 RLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGIS 792

Query: 612 I-DWRGRTGHMCPFTCPADKVYQPCGPSNPSYCYGNDSASLGALPEAGPITEGCFCPEGM 670
           + DWR      CP +CPA+  Y+ CGP+ P+ C G   A+  +     P  EGC C  G 
Sbjct: 793 VGDWRSPAN--CPLSCPANSRYELCGPACPTSCNG---AAAPSNCSGRPCVEGCVCLPG- 846

Query: 671 TLFSTSAQVCVPTGCPRCLGPHGEPVKVGHTVGMD--CQ-ECTCEAATWTLTCRPK-LCP 726
             F  S   CVP     C    G  +  G  V  D  CQ  CTC  AT  +TCR K  CP
Sbjct: 847 --FVASGGACVPASSCGCTF-QGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCP 903

Query: 727 LPPAC 731
               C
Sbjct: 904 AGERC 908



 Score = 96.3 bits (238), Expect = 1e-19
 Identities = 119/463 (25%), Positives = 180/463 (38%), Gaps = 100/463 (21%)

Query: 337  ETWATPNCSE-ATCEG--NNVISLRPRTCPRVEKPTCANG----YPAVKVADQDGCCHHY 389
            E WA   C    TC G  + V     ++CP  E+ +  NG    YP     D+ G     
Sbjct: 874  EVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYP-----DRFG----- 923

Query: 390  QCQCVCSGWGDPHYITFDGTYYTFLDNCTYVLV-----QQIVPVYGHFRVLVDNYFCGAE 444
                 C G GDPHY++FDG  + F+  CTY+LV        +P    FRVLV+N   G++
Sbjct: 924  ----TCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPA---FRVLVENEHRGSQ 976

Query: 445  DGLSCPRSIILEYHQDRVVLTRKPVHGVMTNEIIF-----------------NNKVVSPG 487
              +S  R++ +E    +V + R+    V+ ++++                   + VV   
Sbjct: 977  T-VSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTD 1035

Query: 488  FRKNGIVVS-----RIGVKMYATIPEL--GVQVMFSG------LIFSVEVPFSKFANNTE 534
            F   G+ V+     R+  K+ ++  E   G+   F+G       +       +  A    
Sbjct: 1036 F---GLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNS 1092

Query: 535  GQCXXXXXXXTTPPAPC--LPSPICQLILSK-----------VFEPCHTVIPPLLFYEGC 581
             Q         T P  C  L S + Q + SK            F  CH+ + P      C
Sbjct: 1093 WQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDC 1152

Query: 582  VFDRCHMTDLD-VVCSSLELYAALCASHDICID-WRGRTGHMCPFTCPADKVYQPCGPSN 639
            V+DRC +      +C +L  YAA C +    +  WR     +CP +CP    Y+ C    
Sbjct: 1153 VYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSE--ELCPLSCPPHSHYEACSYGC 1210

Query: 640  PSYCYGNDSASLGALPEAG----PITEGCFCPEGMTLFSTSAQVCVPTGCPRCL--GPHG 693
            P  C        G LP  G       EGC C EG   F+ S + C+P     C+  G + 
Sbjct: 1211 PLSC--------GDLPVPGGCGSECHEGCVCDEG---FALSGESCLPLASCGCVHQGTYH 1259

Query: 694  EPVKVGHTVGMDCQE-CTCEAATWTLTCRPKLCPLPPACPLPG 735
             P +  +  G  C   C C+     ++C    C    AC   G
Sbjct: 1260 PPGQTFYP-GPGCDSLCHCQEG-GLVSCESSSCGPHEACQPSG 1300



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 48/173 (27%), Positives = 63/173 (36%), Gaps = 20/173 (11%)

Query: 280  HCYYALCSQDCQVVRG---VDSDCPSTTLPPAPATSPSISTSE---PVTELGCPNAVPPR 333
            H +Y  CS  C +  G   V   C S              + E   P+   GC +     
Sbjct: 1200 HSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYH 1259

Query: 334  KKGET-WATPNC-SEATCEGNNVISLRPRTCPRVEKPTCANGYPAVKVADQDGCCHHYQC 391
              G+T +  P C S   C+   ++S    +C   E    + G          GC      
Sbjct: 1260 PPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGG--------SLGCVAVGSS 1311

Query: 392  QCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQQ--IVPVYGHFRVLVDNYFCG 442
             C  SG  DPHY TFDG  + F+  C YVL Q     P    F VL +N   G
Sbjct: 1312 TCQASG--DPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWG 1362



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 55/211 (26%), Positives = 75/211 (35%), Gaps = 39/211 (18%)

Query: 687  RCLGPHGEPVKVGHTVGMDCQECTCEAATWTLTCRPKLCPLPPACPLPGFVPVPAAPQAG 746
            RCL P G+   +   +      C    AT       +LCPL  +CP          P + 
Sbjct: 1156 RCLLP-GQSGPLCDALATYAAACQAAGATVHPWRSEELCPL--SCP----------PHSH 1202

Query: 747  QCCPQYSCACNTSRCPKPVGCPEGARAIPTYQEG------ACCPVQNCSWTVCSINGTLY 800
                 Y C  +    P P GC           EG      +C P+ +C    C   GT +
Sbjct: 1203 YEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCG---CVHQGTYH 1259

Query: 801  QPG-AVVSSSLCET-CRCELPGGPPSDAFVVSCETQICNTHCPVGFEYQEQSGQCCGTCV 858
             PG        C++ C C+  G       +VSCE+  C  H     E  + SG   G CV
Sbjct: 1260 PPGQTFYPGPGCDSLCHCQEGG-------LVSCESSSCGPH-----EACQPSGGSLG-CV 1306

Query: 859  QVACVT-NTSKSPAHLFYPGETWSDAGNHCV 888
             V   T   S  P +  + G  +   G  CV
Sbjct: 1307 AVGSSTCQASGDPHYTTFDGRRFDFMGT-CV 1336


>gi|239751787 PREDICTED: hypothetical protein XP_002348012 [Homo
           sapiens]
          Length = 3003

 Score =  108 bits (270), Expect = 3e-23
 Identities = 130/485 (26%), Positives = 187/485 (38%), Gaps = 101/485 (20%)

Query: 311 TSPSISTSEPVTELGCPNAVPPRKKGETWATPNCSEATCEGNNVISLRPRTCPRVEKPTC 370
           T+  I T+E  T LG          G   A    + A C G  V+S    +C  ++   C
Sbjct: 400 TADMIHTAEATTNLGLLTF------GLAKAIGYATAADC-GRTVLSPVEPSCEGMQ---C 449

Query: 371 ANGYPAVKVADQDGCCHHYQCQCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQ-----QI 425
           A G     V  + GC    +   VC   GDPHY TFDG  Y  +  C+Y +V+       
Sbjct: 450 AAGQRCQVVGGKAGCVA--ESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDT 507

Query: 426 VPVYGHFRVLVDNYFCGAEDGLSCPRSIILEYHQDRVVLTRKPVHGVMTNEIIFNNKVVS 485
           +P    F V   N   G+   +S    + +  +   V LTR  V  V+ +    N +   
Sbjct: 508 LPA---FSVEAKNEHRGSR-RVSYVGLVTVRAYSHSVSLTRGEVGFVLVD----NQRSRL 559

Query: 486 PGFRKNGIVVSRIGVKMYATIPELGVQVMFSGLI--------FSVEVPFSKFANNTEGQC 537
           P      + +S   +++Y + P   V+++F GL+         ++ +P ++F +   G C
Sbjct: 560 P------VSLSEGRLRVYQSGPRAVVELVF-GLVVTYDWDCQLALSLP-ARFQDQVCGLC 611

Query: 538 XXXXXXXT----TPPAPCLPSPI------------------CQL---------------- 559
                       TP     P  +                  CQ                 
Sbjct: 612 GNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGD 671

Query: 560 ----ILSKVFEP---CHTVIPPLLFYEGCVFDRCHMTDLDV-VCSSLELYAALCASHDIC 611
               +L+K+  P   CH  + P  F E CV+D C +    + +C  L  YA  C    I 
Sbjct: 672 RLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGIS 731

Query: 612 I-DWRGRTGHMCPFTCPADKVYQPCGPSNPSYCYGNDSASLGALPEAGPITEGCFCPEGM 670
           + DWR      CP +CPA+  Y+ CGP+ P+ C G   A+  +     P  EGC C  G 
Sbjct: 732 VGDWRSPAN--CPLSCPANSRYELCGPACPTSCNG---AAAPSNCSGRPCVEGCVCLPG- 785

Query: 671 TLFSTSAQVCVPTGCPRCLGPHGEPVKVGHTVGMD--CQ-ECTCEAATWTLTCRPK-LCP 726
             F  S   CVP     C    G  +  G  V  D  CQ  CTC  AT  +TCR K  CP
Sbjct: 786 --FVASGGACVPASSCGCTF-QGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCP 842

Query: 727 LPPAC 731
               C
Sbjct: 843 AGERC 847



 Score =  101 bits (251), Expect = 4e-21
 Identities = 124/527 (23%), Positives = 186/527 (35%), Gaps = 113/527 (21%)

Query: 300  CPSTTLPPAPATSPSISTSEPVTELGCP---------------------NAVPPRKKGET 338
            CP++   PAP T+P++     V    C                      N        E 
Sbjct: 1965 CPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEF 2024

Query: 339  WATPNCSE-ATC-EGNNVISLRPRTCPRVEK----PTCANGYPAVKVADQDGCCHHYQCQ 392
            WA   CS+   C  G   +   P +C   E     P+  +G   V  A+           
Sbjct: 2025 WADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAE----------- 2073

Query: 393  CVCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYG------HFRVLVDNYFCGAEDG 446
              C  WGDPHY+T DG  + F   C Y+L     P +G      +F V V N   G++  
Sbjct: 2074 --CQAWGDPHYVTLDGHRFDFQGTCEYLLS---APCHGPPLGAENFTVTVANEHRGSQ-A 2127

Query: 447  LSCPRSIILEYHQDRVVLTRKPVHGVMTNEIIFNNKVVSPGFRKNGIVVSRIGVKMYATI 506
            +S  RS+ L+ +   + L+ +    +  + +      V+  F+ + ++ + +        
Sbjct: 2128 VSYTRSVTLQIYNHSLTLSARWPRKLQVDGVF-----VALPFQLDSLLHAHLSGADVVVT 2182

Query: 507  PELGVQVMFSGLIF-SVEVPFSKFANNTEGQCXXXXXXXTTP------------------ 547
               G+ + F G  F  + VP + +A +  G C                            
Sbjct: 2183 TTSGLSLAFDGDSFVRLRVP-AAYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQG 2241

Query: 548  ---------PAPCLPSP--------ICQLILSK--VFEPCHTVIPPLLFYEGCVFDRCHM 588
                     P+PC P           C +I +      PCH ++PP  +++GC+ D C +
Sbjct: 2242 CGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQV 2301

Query: 589  T-DLDVVCSSLELYAALCASHDICI-DWRGRTGHMCPFTCPADKVYQPCGPSNPSYCYGN 646
                  +C ++  Y A C +    + +W  R    CP  CPA   Y+ CG S P  C   
Sbjct: 2302 QGHPGGLCPAVATYVAACQAAGAQLGEW--RRPDFCPLQCPAHSHYELCGDSCPVSC--- 2356

Query: 647  DSASLGALPEA--GPITEGCFCPEGMTLFSTSAQVCVPTGCPRCLGPHGEPVKVGHTV-- 702
               SL A PE       EGC C  G  L   S   CVP G   CL   G    +G     
Sbjct: 2357 --PSLSA-PEGCESACREGCVCDAGFVL---SGDTCVPVGQCGCL-HDGRYYPLGEVFYP 2409

Query: 703  GMDCQ-ECTCEAATWTLTCRPKLCPLPPACPLPGFVPVPAAPQAGQC 748
            G +C+  C C             C     C L   V    A   G+C
Sbjct: 2410 GPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRC 2456



 Score = 96.3 bits (238), Expect = 1e-19
 Identities = 119/463 (25%), Positives = 180/463 (38%), Gaps = 100/463 (21%)

Query: 337  ETWATPNCSE-ATCEG--NNVISLRPRTCPRVEKPTCANG----YPAVKVADQDGCCHHY 389
            E WA   C    TC G  + V     ++CP  E+ +  NG    YP     D+ G     
Sbjct: 813  EVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYP-----DRFG----- 862

Query: 390  QCQCVCSGWGDPHYITFDGTYYTFLDNCTYVLV-----QQIVPVYGHFRVLVDNYFCGAE 444
                 C G GDPHY++FDG  + F+  CTY+LV        +P    FRVLV+N   G++
Sbjct: 863  ----TCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPA---FRVLVENEHRGSQ 915

Query: 445  DGLSCPRSIILEYHQDRVVLTRKPVHGVMTNEIIF-----------------NNKVVSPG 487
              +S  R++ +E    +V + R+    V+ ++++                   + VV   
Sbjct: 916  T-VSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTD 974

Query: 488  FRKNGIVVS-----RIGVKMYATIPEL--GVQVMFSG------LIFSVEVPFSKFANNTE 534
            F   G+ V+     R+  K+ ++  E   G+   F+G       +       +  A    
Sbjct: 975  F---GLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNS 1031

Query: 535  GQCXXXXXXXTTPPAPC--LPSPICQLILSK-----------VFEPCHTVIPPLLFYEGC 581
             Q         T P  C  L S + Q + SK            F  CH+ + P      C
Sbjct: 1032 WQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDC 1091

Query: 582  VFDRCHMTDLD-VVCSSLELYAALCASHDICID-WRGRTGHMCPFTCPADKVYQPCGPSN 639
            V+DRC +      +C +L  YAA C +    +  WR     +CP +CP    Y+ C    
Sbjct: 1092 VYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSE--ELCPLSCPPHSHYEACSYGC 1149

Query: 640  PSYCYGNDSASLGALPEAG----PITEGCFCPEGMTLFSTSAQVCVPTGCPRCL--GPHG 693
            P  C        G LP  G       EGC C EG   F+ S + C+P     C+  G + 
Sbjct: 1150 PLSC--------GDLPVPGGCGSECHEGCVCDEG---FALSGESCLPLASCGCVHQGTYH 1198

Query: 694  EPVKVGHTVGMDCQE-CTCEAATWTLTCRPKLCPLPPACPLPG 735
             P +  +  G  C   C C+     ++C    C    AC   G
Sbjct: 1199 PPGQTFYP-GPGCDSLCHCQEG-GLVSCESSSCGPHEACQPSG 1239



 Score = 95.9 bits (237), Expect = 2e-19
 Identities = 63/174 (36%), Positives = 79/174 (45%), Gaps = 11/174 (6%)

Query: 565  FEPCHTVIPPLLFYEGCVFDRC-HMTDLDVVCSSLELYAALCASHDICI-DWRGRTGHMC 622
            F  CH  +PP  F++GCV D C    D D++C +L  Y A C +  + I DWR + G  C
Sbjct: 1891 FTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVG--C 1948

Query: 623  PFTCPADKVYQPCGPSNPSYCYGNDSASLGALPEAGPITEGCFCPEGMTLFSTSAQVCVP 682
              TCP +  Y+ CGP  P+ C      +  A+ E GP  EGC C  G  L   SA  CVP
Sbjct: 1949 EITCPENSHYEVCGPPCPASCPSPAPLTTPAVCE-GPCVEGCQCDAGFVL---SADRCVP 2004

Query: 683  --TGCP-RCLGPHGEPVKVGHTVGMDCQECTCEAATWTLTCRPKLCPLPPACPL 733
               GC     G + E        G   Q C C     +L C P  C L   C L
Sbjct: 2005 LNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGL 2058



 Score = 91.3 bits (225), Expect = 4e-18
 Identities = 134/543 (24%), Positives = 203/543 (37%), Gaps = 93/543 (17%)

Query: 280  HCYYALCSQDCQVVRG---VDSDCPSTTLPPAPATSPSISTSE---PVTELGCPNAVPPR 333
            H +Y  CS  C +  G   V   C S              + E   P+   GC +     
Sbjct: 1139 HSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYH 1198

Query: 334  KKGET-WATPNC-SEATCEGNNVISLRPRTCPRVEKPTCANGYPAVKVADQDGCCHHYQC 391
              G+T +  P C S   C+   ++S    +C   E    + G          GC      
Sbjct: 1199 PPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGG--------SLGCVAVGSS 1250

Query: 392  QCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIV--PVYGHFRVLVDNYFCGAEDGLSC 449
             C  SG  DPHY TFDG  + F+  C YVL Q     P    F VL +N   G    +S 
Sbjct: 1251 TCQASG--DPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWG-NGRVSV 1307

Query: 450  PRSIILEYHQDRVVLTRKP----VHGVMTN--EIIFNNKVVSPGFRKNGIVVSRIGVKMY 503
             R I ++     + L ++     V+GV      ++ N ++ +     + ++ +  G+++ 
Sbjct: 1308 TRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVA 1367

Query: 504  --------ATIPELGVQVM--------------FSGLIFSVEVPFSKFANNTEGQCXXXX 541
                     T+P    Q M              F     S     ++F N+ E       
Sbjct: 1368 YDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSP 1427

Query: 542  XXXTTPPAP----CLPSPICQLILSKVFEP----------------CHTVIPPLLFYEGC 581
                TP  P    C+PS  C   L K ++                 CH ++ P    + C
Sbjct: 1428 CLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDC 1487

Query: 582  VFDRC-HMTDLDVVCSSLELYAALCASHDICID-WRGRTGHMCPFTCPADKVYQPCGPSN 639
            +FD C    +L ++CS++  Y + C +    ++ WR  T   CP  CP +  Y+ C  + 
Sbjct: 1488 IFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTET--FCPMECPPNSHYELCADTC 1545

Query: 640  PSYCYGNDSASLGALPEA-GPITEGCFCPEGMTLFSTSAQVCVPTGCPRCL--GPHGEPV 696
               C     ++L A P+      EGC C  G   F  + Q CVP     C   G + EP 
Sbjct: 1546 SLGC-----SALSAPPQCQDGCAEGCQCDSG---FLYNGQACVPIQQCGCYHNGVYYEPE 1597

Query: 697  KVGHTVGMD-C-QECTCEAATWTLTCRPKLCPLPPACPLPGFV--PVPAAPQAGQCC-PQ 751
            +   TV +D C Q+CTC A    + C+   C     C   G +   V   P  G  C PQ
Sbjct: 1598 Q---TVLIDNCRQQCTCHAGK-GMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQ 1653

Query: 752  YSC 754
             +C
Sbjct: 1654 ETC 1656



 Score = 67.0 bits (162), Expect = 9e-11
 Identities = 53/174 (30%), Positives = 75/174 (43%), Gaps = 21/174 (12%)

Query: 565  FEPCHTVIPPLLFYEGCVFDRC-HMTDLDVVCSSLELYAALCASHDICI-DWRGRTGHMC 622
            F  C  V+ P  ++  CV+D C    D   +C SL  Y A C +  + +  W  RT   C
Sbjct: 2660 FATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPW--RTDSFC 2717

Query: 623  PFTCPADKVYQPCGPSNPSYCYGNDSASLGALPEAGPITEGCFCPEGMTLFSTSAQVCVP 682
            P  CPA   Y  C  +    C G+ +A  G         EGC C +    F  S  VC+P
Sbjct: 2718 PLHCPAHSHYSICTRT----CQGSCAALSGLTGCTTRCFEGCECDD---RFLLSQGVCIP 2770

Query: 683  T---GCPRCLGPHGEPVKVGHT-VGMDCQE-CTCEAATWTLTCRPKLCPLPPAC 731
                GC      +G  + V  + +  DC E C+C +++  LTC+   CP    C
Sbjct: 2771 VQDCGCTH----NGRYLPVNSSLLTSDCSERCSCSSSS-GLTCQAAGCPPGRVC 2819



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 48/168 (28%), Positives = 63/168 (37%), Gaps = 35/168 (20%)

Query: 280  HCYYALCSQDCQVVRGVDSDCPSTTLPPAPATSP------------SISTSEPVTELGCP 327
            H +Y LC   C V       CPS + P    ++             S  T  PV + GC 
Sbjct: 2342 HSHYELCGDSCPV------SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCL 2395

Query: 328  NAVPPRKKGET-WATPNCSEATCE---GNNVISLRPRTCPRVEKPTCANGYPAVKVADQD 383
            +       GE  +  P C E  CE   G +V       C   E+    +G  A       
Sbjct: 2396 HDGRYYPLGEVFYPGPEC-ERRCECGPGGHVTCQEGAACGPHEECRLEDGVQA------- 2447

Query: 384  GCCHHYQC-QCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYG 430
              CH   C +C+ +G    HYIT DG  Y    +C+YVL Q   P  G
Sbjct: 2448 --CHATGCGRCLANG--GIHYITLDGRVYDLHGSCSYVLAQVCHPKPG 2491



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 55/211 (26%), Positives = 75/211 (35%), Gaps = 39/211 (18%)

Query: 687  RCLGPHGEPVKVGHTVGMDCQECTCEAATWTLTCRPKLCPLPPACPLPGFVPVPAAPQAG 746
            RCL P G+   +   +      C    AT       +LCPL  +CP          P + 
Sbjct: 1095 RCLLP-GQSGPLCDALATYAAACQAAGATVHPWRSEELCPL--SCP----------PHSH 1141

Query: 747  QCCPQYSCACNTSRCPKPVGCPEGARAIPTYQEG------ACCPVQNCSWTVCSINGTLY 800
                 Y C  +    P P GC           EG      +C P+ +C    C   GT +
Sbjct: 1142 YEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCG---CVHQGTYH 1198

Query: 801  QPG-AVVSSSLCET-CRCELPGGPPSDAFVVSCETQICNTHCPVGFEYQEQSGQCCGTCV 858
             PG        C++ C C+  G       +VSCE+  C  H     E  + SG   G CV
Sbjct: 1199 PPGQTFYPGPGCDSLCHCQEGG-------LVSCESSSCGPH-----EACQPSGGSLG-CV 1245

Query: 859  QVACVT-NTSKSPAHLFYPGETWSDAGNHCV 888
             V   T   S  P +  + G  +   G  CV
Sbjct: 1246 AVGSSTCQASGDPHYTTFDGRRFDFMGT-CV 1275



 Score = 38.1 bits (87), Expect = 0.044
 Identities = 49/211 (23%), Positives = 66/211 (31%), Gaps = 64/211 (30%)

Query: 680  CVPTGCPRCLGPHGEPVKVGHTVGM----DCQECTCEA---------------------- 713
            C P GCP CL     P +     G          TC+A                      
Sbjct: 2628 CGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDK 2687

Query: 714  -------ATWTLTCRP-----------KLCPLPPACPLPGFVPVPAAPQAGQCCPQYSCA 755
                   A +T  C+              CPL   CP      +      G C       
Sbjct: 2688 AFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLH--CPAHSHYSICTRTCQGSCAALSGLT 2745

Query: 756  CNTSRCPKPVGCPEGARAIPTYQEGACCPVQNCSWTVCSINGTLYQP--GAVVSSSLCET 813
              T+RC +  GC    R +    +G C PVQ+C    C+ NG  Y P   ++++S   E 
Sbjct: 2746 GCTTRCFE--GCECDDRFL--LSQGVCIPVQDCG---CTHNGR-YLPVNSSLLTSDCSER 2797

Query: 814  C--------RCELPGGPPSDAFVVSCETQIC 836
            C         C+  G PP     V  E + C
Sbjct: 2798 CSCSSSSGLTCQAAGCPPGRVCEVKAEARNC 2828


>gi|154146262 Fc fragment of IgG binding protein [Homo sapiens]
          Length = 5405

 Score =  108 bits (270), Expect = 3e-23
 Identities = 130/485 (26%), Positives = 187/485 (38%), Gaps = 101/485 (20%)

Query: 311 TSPSISTSEPVTELGCPNAVPPRKKGETWATPNCSEATCEGNNVISLRPRTCPRVEKPTC 370
           T+  I T+E  T LG          G   A    + A C G  V+S    +C  ++   C
Sbjct: 400 TADMIHTAEATTNLGLLTF------GLAKAIGYATAADC-GRTVLSPVEPSCEGMQ---C 449

Query: 371 ANGYPAVKVADQDGCCHHYQCQCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQ-----QI 425
           A G     V  + GC    +   VC   GDPHY TFDG  Y  +  C+Y +V+       
Sbjct: 450 AAGQRCQVVGGKAGCVA--ESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDT 507

Query: 426 VPVYGHFRVLVDNYFCGAEDGLSCPRSIILEYHQDRVVLTRKPVHGVMTNEIIFNNKVVS 485
           +P    F V   N   G+   +S    + +  +   V LTR  V  V+ +    N +   
Sbjct: 508 LPA---FSVEAKNEHRGSR-RVSYVGLVTVRAYSHSVSLTRGEVGFVLVD----NQRSRL 559

Query: 486 PGFRKNGIVVSRIGVKMYATIPELGVQVMFSGLI--------FSVEVPFSKFANNTEGQC 537
           P      + +S   +++Y + P   V+++F GL+         ++ +P ++F +   G C
Sbjct: 560 P------VSLSEGRLRVYQSGPRAVVELVF-GLVVTYDWDCQLALSLP-ARFQDQVCGLC 611

Query: 538 XXXXXXXT----TPPAPCLPSPI------------------CQL---------------- 559
                       TP     P  +                  CQ                 
Sbjct: 612 GNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGD 671

Query: 560 ----ILSKVFEP---CHTVIPPLLFYEGCVFDRCHMTDLDV-VCSSLELYAALCASHDIC 611
               +L+K+  P   CH  + P  F E CV+D C +    + +C  L  YA  C    I 
Sbjct: 672 RLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGIS 731

Query: 612 I-DWRGRTGHMCPFTCPADKVYQPCGPSNPSYCYGNDSASLGALPEAGPITEGCFCPEGM 670
           + DWR      CP +CPA+  Y+ CGP+ P+ C G   A+  +     P  EGC C  G 
Sbjct: 732 VGDWRSPAN--CPLSCPANSRYELCGPACPTSCNG---AAAPSNCSGRPCVEGCVCLPG- 785

Query: 671 TLFSTSAQVCVPTGCPRCLGPHGEPVKVGHTVGMD--CQ-ECTCEAATWTLTCRPK-LCP 726
             F  S   CVP     C    G  +  G  V  D  CQ  CTC  AT  +TCR K  CP
Sbjct: 786 --FVASGGACVPASSCGCTF-QGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCP 842

Query: 727 LPPAC 731
               C
Sbjct: 843 AGERC 847



 Score =  106 bits (265), Expect = 1e-22
 Identities = 123/513 (23%), Positives = 185/513 (36%), Gaps = 116/513 (22%)

Query: 298  SDCPSTTLPPAPATSPSISTSEPVTELGCP---------------------NAVPPRKKG 336
            S CP++   PAP T+P++     V    C                      N        
Sbjct: 1961 SPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGS 2020

Query: 337  ETWATPNCSE-ATC-EGNNVISLRPRTCPRVEK----PTCANGYPAVKVADQDGCCHHYQ 390
            E WA   CS+   C  G   +   P +C   E     P+  +G   V  A+         
Sbjct: 2021 EFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAE--------- 2071

Query: 391  CQCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYG------HFRVLVDNYFCGAE 444
                C  WGDPHY+T DG  + F   C Y+L     P +G      +F V V N   G++
Sbjct: 2072 ----CQAWGDPHYVTLDGHRFNFQGTCEYLLS---APCHGPPLGAENFTVTVANEHRGSQ 2124

Query: 445  DGLSCPRSIILEYHQDRVVLTRKPVHGVMTNEIIFNNKVVSPGFRKNGIVVSRIGVKMYA 504
              +S  RS+ L+ +   + L+ +    +  + +      V+  F+ + ++ + +      
Sbjct: 2125 -AVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVF-----VTLPFQLDSLLHAHLSGADVV 2178

Query: 505  TIPELGVQVMFSGLIF-SVEVPFSKFANNTEGQCXXXXXXXTTP---------------- 547
                 G+ + F G  F  + VP + +A +  G C                          
Sbjct: 2179 VTTTSGLSLAFDGDSFVRLRVP-AAYAGSLCGLCGNYNQDPADDLKAVGGKPAGWQVGGA 2237

Query: 548  -----------PAPCLPSP--------ICQLILSK--VFEPCHTVIPPLLFYEGCVFDRC 586
                       P+PC P           C +I +      PCH ++PP  +++GC+ D C
Sbjct: 2238 QGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDAC 2297

Query: 587  HMT-DLDVVCSSLELYAALCASHDICI-DWRGRTGHMCPFTCPADKVYQPCGPSNPSYCY 644
             +      +C ++  Y A C +    + +W  R    CPF CPA   Y+ CG S P  C 
Sbjct: 2298 QVQGHPGGLCPAVATYVAACQAAGAQLREW--RRPDFCPFQCPAHSHYELCGDSCPGSC- 2354

Query: 645  GNDSASLGALPEA--GPITEGCFCPEGMTLFSTSAQVCVPTGCPRCLGPHGE---PVKVG 699
                 SL A PE       EGC C  G  L   S   CVP G   CL  H +   P+   
Sbjct: 2355 ----PSLSA-PEGCESACREGCVCDAGFVL---SGDTCVPVGQCGCL--HDDRYYPLGQT 2404

Query: 700  HTVGMDCQE-CTCEAATWTLTCRPKLCPLPPAC 731
               G  C   C C      ++C P  C     C
Sbjct: 2405 FYPGPGCDSLCRCREG-GEVSCEPSSCGPHETC 2436



 Score =  105 bits (261), Expect = 3e-22
 Identities = 122/511 (23%), Positives = 184/511 (36%), Gaps = 116/511 (22%)

Query: 300  CPSTTLPPAPATSPSISTSEPVTELGCP---------------------NAVPPRKKGET 338
            CP++   PAP T+P++     V    C                      N        E 
Sbjct: 3164 CPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEF 3223

Query: 339  WATPNCSE-ATC-EGNNVISLRPRTCPRVEK----PTCANGYPAVKVADQDGCCHHYQCQ 392
            WA   CS+   C  G   +   P +C   E     P+  +G   V  A+           
Sbjct: 3224 WADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAE----------- 3272

Query: 393  CVCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYG------HFRVLVDNYFCGAEDG 446
              C  WGDPHY+T DG  + F   C Y+L     P +G      +F V V N   G++  
Sbjct: 3273 --CQAWGDPHYVTLDGHRFDFQGTCEYLLS---APCHGPPLGAENFTVTVANEHRGSQ-A 3326

Query: 447  LSCPRSIILEYHQDRVVLTRKPVHGVMTNEIIFNNKVVSPGFRKNGIVVSRIGVKMYATI 506
            +S  RS+ L+ +   + L+ +    +  + +      V+  F+ + ++ + +        
Sbjct: 3327 VSYTRSVTLQIYNHSLTLSARWPRKLQVDGVF-----VTLPFQLDSLLHAHLSGADVVVT 3381

Query: 507  PELGVQVMFSGLIF-SVEVPFSKFANNTEGQCXXXXXXXTTP------------------ 547
               G+ + F G  F  + VP + +A +  G C                            
Sbjct: 3382 TTSGLSLAFDGDSFVRLRVP-AAYAGSLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQG 3440

Query: 548  ---------PAPCLPSP--------ICQLILSK--VFEPCHTVIPPLLFYEGCVFDRCHM 588
                     P+PC P           C +I +      PCH ++PP  +++GC+ D C +
Sbjct: 3441 CGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQV 3500

Query: 589  T-DLDVVCSSLELYAALCASHDICI-DWRGRTGHMCPFTCPADKVYQPCGPSNPSYCYGN 646
                  +C ++  Y A C +    + +W  R    CPF CPA   Y+ CG S P  C   
Sbjct: 3501 QGHPGGLCPAVATYVAACQAAGAQLREW--RRPDFCPFQCPAHSHYELCGDSCPGSC--- 3555

Query: 647  DSASLGALPEA--GPITEGCFCPEGMTLFSTSAQVCVPTGCPRCLGPHGE---PVKVGHT 701
               SL A PE       EGC C  G  L   S   CVP G   CL  H +   P+     
Sbjct: 3556 --PSLSA-PEGCESACREGCVCDAGFVL---SGDTCVPVGQCGCL--HDDRYYPLGQTFY 3607

Query: 702  VGMDCQE-CTCEAATWTLTCRPKLCPLPPAC 731
             G  C   C C      ++C P  C     C
Sbjct: 3608 PGPGCDSLCRCREG-GEVSCEPSSCGPHETC 3637



 Score =  101 bits (251), Expect = 4e-21
 Identities = 124/527 (23%), Positives = 186/527 (35%), Gaps = 113/527 (21%)

Query: 300  CPSTTLPPAPATSPSISTSEPVTELGCP---------------------NAVPPRKKGET 338
            CP++   PAP T+P++     V    C                      N        E 
Sbjct: 4365 CPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEF 4424

Query: 339  WATPNCSE-ATC-EGNNVISLRPRTCPRVEK----PTCANGYPAVKVADQDGCCHHYQCQ 392
            WA   CS+   C  G   +   P +C   E     P+  +G   V  A+           
Sbjct: 4425 WADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAE----------- 4473

Query: 393  CVCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYG------HFRVLVDNYFCGAEDG 446
              C  WGDPHY+T DG  + F   C Y+L     P +G      +F V V N   G++  
Sbjct: 4474 --CQAWGDPHYVTLDGHRFDFQGTCEYLLS---APCHGPPLGAENFTVTVANEHRGSQ-A 4527

Query: 447  LSCPRSIILEYHQDRVVLTRKPVHGVMTNEIIFNNKVVSPGFRKNGIVVSRIGVKMYATI 506
            +S  RS+ L+ +   + L+ +    +  + +      V+  F+ + ++ + +        
Sbjct: 4528 VSYTRSVTLQIYNHSLTLSARWPRKLQVDGVF-----VALPFQLDSLLHAHLSGADVVVT 4582

Query: 507  PELGVQVMFSGLIF-SVEVPFSKFANNTEGQCXXXXXXXTTP------------------ 547
               G+ + F G  F  + VP + +A +  G C                            
Sbjct: 4583 TTSGLSLAFDGDSFVRLRVP-AAYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQG 4641

Query: 548  ---------PAPCLPSP--------ICQLILSK--VFEPCHTVIPPLLFYEGCVFDRCHM 588
                     P+PC P           C +I +      PCH ++PP  +++GC+ D C +
Sbjct: 4642 CGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQV 4701

Query: 589  T-DLDVVCSSLELYAALCASHDICI-DWRGRTGHMCPFTCPADKVYQPCGPSNPSYCYGN 646
                  +C ++  Y A C +    + +W  R    CP  CPA   Y+ CG S P  C   
Sbjct: 4702 QGHPGGLCPAVATYVAACQAAGAQLGEW--RRPDFCPLQCPAHSHYELCGDSCPVSC--- 4756

Query: 647  DSASLGALPEA--GPITEGCFCPEGMTLFSTSAQVCVPTGCPRCLGPHGEPVKVGHTV-- 702
               SL A PE       EGC C  G  L   S   CVP G   CL   G    +G     
Sbjct: 4757 --PSLSA-PEGCESACREGCVCDAGFVL---SGDTCVPVGQCGCL-HDGRYYPLGEVFYP 4809

Query: 703  GMDCQ-ECTCEAATWTLTCRPKLCPLPPACPLPGFVPVPAAPQAGQC 748
            G +C+  C C             C     C L   V    A   G+C
Sbjct: 4810 GPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRC 4856



 Score = 97.8 bits (242), Expect = 5e-20
 Identities = 155/655 (23%), Positives = 226/655 (34%), Gaps = 143/655 (21%)

Query: 202  PRGCPVTSVTPYGTSPTNALYPSLSTSMVSASVASTSVASSSVASSSVAYSTQTCFCNVA 261
            P  C V S T    +P + L P          +               A +T    C  A
Sbjct: 2263 PDACGVISATDGPLAPCHGLVPP--AQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAA 2320

Query: 262  DRLYPAGSTIYRHRDLA-----GHCYYALCSQDCQVVRGVDSDCPSTTLPPAPATSP--- 313
                 A    +R  D        H +Y LC   C         CPS + P    ++    
Sbjct: 2321 G----AQLREWRRPDFCPFQCPAHSHYELCGDSCP------GSCPSLSAPEGCESACREG 2370

Query: 314  ---------SISTSEPVTELGCPNAVPPRKKGET-WATPNC-SEATCEGNNVISLRPRTC 362
                     S  T  PV + GC +       G+T +  P C S   C     +S  P +C
Sbjct: 2371 CVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSC 2430

Query: 363  PRVEKPTCANGYPAVKVADQDGCCHHYQCQCVCSGWGDPHYITFDGTYYTFLDNCTYVLV 422
               E  TC     ++      GC       C  SG  DPHY TFDG  + F+  C YVL 
Sbjct: 2431 GPHE--TCRPSGGSL------GCVAVGSTTCQASG--DPHYTTFDGRRFDFMGTCVYVLA 2480

Query: 423  QQIV--PVYGHFRVLVDNYFCGAEDGLSCPRSIILEYHQDRVVLTRKP----VHGVMTN- 475
            Q     P    F VL +N   G    +S  R I ++     + L ++     V+GV    
Sbjct: 2481 QTCGTRPGLHRFAVLQENVAWG-NGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKL 2539

Query: 476  -EIIFNNKVVSPGFRKNGIVVSRIGVKMY--------ATIPELGVQVMFSGLIFSVEV-P 525
              ++ N ++ +     + ++ +  G+++          T+P    Q+M  GL  +    P
Sbjct: 2540 PVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLM-CGLCGNYNGDP 2598

Query: 526  FSKFANNTEGQCXXXXXXXTT-----PPAPCLPSPICQL--------------------- 559
               F      Q         +     P +PCLP P C                       
Sbjct: 2599 KDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSEGCIPSEECPPELEKKYQK 2658

Query: 560  -----ILSKVFEP---CHTVIPPLLFYEGCVFDRC-HMTDLDVVCSSLELYAALCASHDI 610
                 +LS    P   CH ++ P    + C+FD C    +L ++CS++  Y + C +   
Sbjct: 2659 EEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGG 2718

Query: 611  CID-WRGRTGHMCPFTCPADKVYQPCGPSNPSYCYGNDSASLGALPEAGPI------TEG 663
             ++ WR  T   CP  CP +  Y+ C           D+ SLG    + P+       EG
Sbjct: 2719 QVEPWRNET--FCPMECPQNSHYELCA----------DTCSLGCSALSAPLQCPDGCAEG 2766

Query: 664  CFCPEGMTLFSTSAQVCVPTGCPRCL--GPHGEPVKVGHTVGMD-C-QECTCEAATWTLT 719
            C C  G   F  + Q CVP     C   G + EP +   TV +D C Q+CTC      + 
Sbjct: 2767 CQCDSG---FLYNGQACVPIQQCGCYHNGAYYEPEQ---TVLIDNCRQQCTCHVGK-VVV 2819

Query: 720  CRPKLCPLPPACPLPGFV----------PVPAAPQ--------AGQCCPQYSCAC 756
            C+   C     C   G +           V   PQ         G C P Y   C
Sbjct: 2820 CQEHSCKPGQVCQPSGGILSCVNKDPCHGVTCRPQETCKEQGGQGVCLPNYEATC 2874



 Score = 97.1 bits (240), Expect = 8e-20
 Identities = 154/638 (24%), Positives = 226/638 (35%), Gaps = 128/638 (20%)

Query: 202  PRGCPVTSVTPYGTSPTNALYPSLSTSMVSASVASTSVASSSVASSSVAYSTQTCFCNVA 261
            P  C V S T    +P + L P          +               A +T    C  A
Sbjct: 3464 PDACGVISATDGPLAPCHGLVPP--AQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAA 3521

Query: 262  DRLYPAGSTIYRHRDLA-----GHCYYALCSQDCQVVRGVDSDCPSTTLPPAPATSP--- 313
                 A    +R  D        H +Y LC   C         CPS + P    ++    
Sbjct: 3522 G----AQLREWRRPDFCPFQCPAHSHYELCGDSCP------GSCPSLSAPEGCESACREG 3571

Query: 314  ---------SISTSEPVTELGCPNAVPPRKKGET-WATPNC-SEATCEGNNVISLRPRTC 362
                     S  T  PV + GC +       G+T +  P C S   C     +S  P +C
Sbjct: 3572 CVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSC 3631

Query: 363  PRVEKPTCANGYPAVKVADQDGCCHHYQCQCVCSGWGDPHYITFDGTYYTFLDNCTYVLV 422
               E  TC     ++      GC       C  SG  DPHY TFDG  + F+  C YVL 
Sbjct: 3632 GPHE--TCRPSGGSL------GCVAVGSTTCQASG--DPHYTTFDGHRFDFMGTCVYVLA 3681

Query: 423  QQIV--PVYGHFRVLVDNYFCGAEDGLSCPRSIILEYHQDRVVLTRKP----VHGVMTN- 475
            Q     P    F VL +N   G    +S  R I ++     + L ++     V+GV    
Sbjct: 3682 QTCGTRPGLHRFAVLQENVAWG-NGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKL 3740

Query: 476  -EIIFNNKVVSPGFRKNGIVVSRIGVKMY--------ATIPELGVQVMFSGLIFSVEV-P 525
              ++ N ++ +     + ++ +  G+++          T+P    Q+M  GL  +    P
Sbjct: 3741 PVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLM-CGLCGNYNGDP 3799

Query: 526  FSKFANNTEGQCXXXXXXXTT-----PPAPCLPSPICQL--------------------- 559
               F      Q         +     P +PCLP P C                       
Sbjct: 3800 KDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSAGCIPSDKCPPELEKKYQK 3859

Query: 560  -----ILSKVFEP---CHTVIPPLLFYEGCVFDRC-HMTDLDVVCSSLELYAALCASHDI 610
                 +LS    P   CH ++ P    + C+FD C    +L ++CS++  Y + C +   
Sbjct: 3860 EEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGG 3919

Query: 611  CID-WRGRTGHMCPFTCPADKVYQPCGPSNPSYCYGNDSASLGALPEAGPI------TEG 663
             ++ WR  T   CP  CP +  Y+ C           D+ SLG    + P+       EG
Sbjct: 3920 HVEPWRNET--FCPMECPQNSHYELCA----------DTCSLGCSALSAPLQCPDGCAEG 3967

Query: 664  CFCPEGMTLFSTSAQVCVPTGCPRCL--GPHGEPVKVGHTVGMD-C-QECTCEAATWTLT 719
            C C  G   F  + Q CVP     C   G + EP +   TV +D C Q+CTC      + 
Sbjct: 3968 CQCDSG---FLYNGQACVPIQQCGCYHNGVYYEPEQ---TVLIDNCRQQCTCHVGK-VVV 4020

Query: 720  CRPKLCPLPPACPLPGFV--PVPAAPQAGQCC-PQYSC 754
            C+   C     C   G +   V   P  G  C PQ +C
Sbjct: 4021 CQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETC 4058



 Score = 96.3 bits (238), Expect = 1e-19
 Identities = 119/463 (25%), Positives = 180/463 (38%), Gaps = 100/463 (21%)

Query: 337  ETWATPNCSE-ATCEG--NNVISLRPRTCPRVEKPTCANG----YPAVKVADQDGCCHHY 389
            E WA   C    TC G  + V     ++CP  E+ +  NG    YP     D+ G     
Sbjct: 813  EVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYP-----DRFG----- 862

Query: 390  QCQCVCSGWGDPHYITFDGTYYTFLDNCTYVLV-----QQIVPVYGHFRVLVDNYFCGAE 444
                 C G GDPHY++FDG  + F+  CTY+LV        +P    FRVLV+N   G++
Sbjct: 863  ----TCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPA---FRVLVENEHRGSQ 915

Query: 445  DGLSCPRSIILEYHQDRVVLTRKPVHGVMTNEIIF-----------------NNKVVSPG 487
              +S  R++ +E    +V + R+    V+ ++++                   + VV   
Sbjct: 916  T-VSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTD 974

Query: 488  FRKNGIVVS-----RIGVKMYATIPEL--GVQVMFSG------LIFSVEVPFSKFANNTE 534
            F   G+ V+     R+  K+ ++  E   G+   F+G       +       +  A    
Sbjct: 975  F---GLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNS 1031

Query: 535  GQCXXXXXXXTTPPAPC--LPSPICQLILSK-----------VFEPCHTVIPPLLFYEGC 581
             Q         T P  C  L S + Q + SK            F  CH+ + P      C
Sbjct: 1032 WQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDC 1091

Query: 582  VFDRCHMTDLD-VVCSSLELYAALCASHDICID-WRGRTGHMCPFTCPADKVYQPCGPSN 639
            V+DRC +      +C +L  YAA C +    +  WR     +CP +CP    Y+ C    
Sbjct: 1092 VYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSE--ELCPLSCPPHSHYEACSYGC 1149

Query: 640  PSYCYGNDSASLGALPEAG----PITEGCFCPEGMTLFSTSAQVCVPTGCPRCL--GPHG 693
            P  C        G LP  G       EGC C EG   F+ S + C+P     C+  G + 
Sbjct: 1150 PLSC--------GDLPVPGGCGSECHEGCVCDEG---FALSGESCLPLASCGCVHQGTYH 1198

Query: 694  EPVKVGHTVGMDCQE-CTCEAATWTLTCRPKLCPLPPACPLPG 735
             P +  +  G  C   C C+     ++C    C    AC   G
Sbjct: 1199 PPGQTFYP-GPGCDSLCHCQEG-GLVSCESSSCGPHEACQPSG 1239



 Score = 95.9 bits (237), Expect = 2e-19
 Identities = 63/174 (36%), Positives = 79/174 (45%), Gaps = 11/174 (6%)

Query: 565  FEPCHTVIPPLLFYEGCVFDRC-HMTDLDVVCSSLELYAALCASHDICI-DWRGRTGHMC 622
            F  CH  +PP  F++GCV D C    D D++C +L  Y A C +  + I DWR + G  C
Sbjct: 3090 FTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVG--C 3147

Query: 623  PFTCPADKVYQPCGPSNPSYCYGNDSASLGALPEAGPITEGCFCPEGMTLFSTSAQVCVP 682
              TCP +  Y+ CGP  P+ C      +  A+ E GP  EGC C  G  L   SA  CVP
Sbjct: 3148 EITCPENSHYEVCGPPCPASCPSPAPLTTPAVCE-GPCVEGCQCDAGFVL---SADRCVP 3203

Query: 683  --TGCP-RCLGPHGEPVKVGHTVGMDCQECTCEAATWTLTCRPKLCPLPPACPL 733
               GC     G + E        G   Q C C     +L C P  C L   C L
Sbjct: 3204 LNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGL 3257



 Score = 95.9 bits (237), Expect = 2e-19
 Identities = 63/174 (36%), Positives = 79/174 (45%), Gaps = 11/174 (6%)

Query: 565  FEPCHTVIPPLLFYEGCVFDRC-HMTDLDVVCSSLELYAALCASHDICI-DWRGRTGHMC 622
            F  CH  +PP  F++GCV D C    D D++C +L  Y A C +  + I DWR + G  C
Sbjct: 4291 FTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVG--C 4348

Query: 623  PFTCPADKVYQPCGPSNPSYCYGNDSASLGALPEAGPITEGCFCPEGMTLFSTSAQVCVP 682
              TCP +  Y+ CGP  P+ C      +  A+ E GP  EGC C  G  L   SA  CVP
Sbjct: 4349 EITCPENSHYEVCGPPCPASCPSPAPLTTPAVCE-GPCVEGCQCDAGFVL---SADRCVP 4404

Query: 683  --TGCP-RCLGPHGEPVKVGHTVGMDCQECTCEAATWTLTCRPKLCPLPPACPL 733
               GC     G + E        G   Q C C     +L C P  C L   C L
Sbjct: 4405 LNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGL 4458



 Score = 92.8 bits (229), Expect = 2e-18
 Identities = 62/174 (35%), Positives = 78/174 (44%), Gaps = 11/174 (6%)

Query: 565  FEPCHTVIPPLLFYEGCVFDRC-HMTDLDVVCSSLELYAALCASHDICI-DWRGRTGHMC 622
            F  CH  +PP  F++GCV D C    D D++C +L  Y A C +  + I DWR + G  C
Sbjct: 1889 FTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVG--C 1946

Query: 623  PFTCPADKVYQPCGPSNPSYCYGNDSASLGALPEAGPITEGCFCPEGMTLFSTSAQVCVP 682
              TCP +  Y+ CG   P+ C      +  A+ E GP  EGC C  G  L   SA  CVP
Sbjct: 1947 EITCPENSHYEVCGSPCPASCPSPAPLTTPAVCE-GPCVEGCQCDAGFVL---SADRCVP 2002

Query: 683  --TGCP-RCLGPHGEPVKVGHTVGMDCQECTCEAATWTLTCRPKLCPLPPACPL 733
               GC     G + E        G   Q C C     +L C P  C L   C L
Sbjct: 2003 LNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGL 2056



 Score = 91.3 bits (225), Expect = 4e-18
 Identities = 134/543 (24%), Positives = 203/543 (37%), Gaps = 93/543 (17%)

Query: 280  HCYYALCSQDCQVVRG---VDSDCPSTTLPPAPATSPSISTSE---PVTELGCPNAVPPR 333
            H +Y  CS  C +  G   V   C S              + E   P+   GC +     
Sbjct: 1139 HSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYH 1198

Query: 334  KKGET-WATPNC-SEATCEGNNVISLRPRTCPRVEKPTCANGYPAVKVADQDGCCHHYQC 391
              G+T +  P C S   C+   ++S    +C   E    + G          GC      
Sbjct: 1199 PPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGG--------SLGCVAVGSS 1250

Query: 392  QCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIV--PVYGHFRVLVDNYFCGAEDGLSC 449
             C  SG  DPHY TFDG  + F+  C YVL Q     P    F VL +N   G    +S 
Sbjct: 1251 TCQASG--DPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWG-NGRVSV 1307

Query: 450  PRSIILEYHQDRVVLTRKP----VHGVMTN--EIIFNNKVVSPGFRKNGIVVSRIGVKMY 503
             R I ++     + L ++     V+GV      ++ N ++ +     + ++ +  G+++ 
Sbjct: 1308 TRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVA 1367

Query: 504  --------ATIPELGVQVM--------------FSGLIFSVEVPFSKFANNTEGQCXXXX 541
                     T+P    Q M              F     S     ++F N+ E       
Sbjct: 1368 YDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSP 1427

Query: 542  XXXTTPPAP----CLPSPICQLILSKVFEP----------------CHTVIPPLLFYEGC 581
                TP  P    C+PS  C   L K ++                 CH ++ P    + C
Sbjct: 1428 CLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDC 1487

Query: 582  VFDRC-HMTDLDVVCSSLELYAALCASHDICID-WRGRTGHMCPFTCPADKVYQPCGPSN 639
            +FD C    +L ++CS++  Y + C +    ++ WR  T   CP  CP +  Y+ C  + 
Sbjct: 1488 IFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTET--FCPMECPPNSHYELCADTC 1545

Query: 640  PSYCYGNDSASLGALPEA-GPITEGCFCPEGMTLFSTSAQVCVPTGCPRCL--GPHGEPV 696
               C     ++L A P+      EGC C  G   F  + Q CVP     C   G + EP 
Sbjct: 1546 SLGC-----SALSAPPQCQDGCAEGCQCDSG---FLYNGQACVPIQQCGCYHNGVYYEPE 1597

Query: 697  KVGHTVGMD-C-QECTCEAATWTLTCRPKLCPLPPACPLPGFV--PVPAAPQAGQCC-PQ 751
            +   TV +D C Q+CTC A    + C+   C     C   G +   V   P  G  C PQ
Sbjct: 1598 Q---TVLIDNCRQQCTCHAGK-GMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQ 1653

Query: 752  YSC 754
             +C
Sbjct: 1654 ETC 1656



 Score = 67.0 bits (162), Expect = 9e-11
 Identities = 53/174 (30%), Positives = 75/174 (43%), Gaps = 21/174 (12%)

Query: 565  FEPCHTVIPPLLFYEGCVFDRC-HMTDLDVVCSSLELYAALCASHDICI-DWRGRTGHMC 622
            F  C  V+ P  ++  CV+D C    D   +C SL  Y A C +  + +  W  RT   C
Sbjct: 5060 FATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPW--RTDSFC 5117

Query: 623  PFTCPADKVYQPCGPSNPSYCYGNDSASLGALPEAGPITEGCFCPEGMTLFSTSAQVCVP 682
            P  CPA   Y  C  +    C G+ +A  G         EGC C +    F  S  VC+P
Sbjct: 5118 PLHCPAHSHYSICTRT----CQGSCAALSGLTGCTTRCFEGCECDD---RFLLSQGVCIP 5170

Query: 683  T---GCPRCLGPHGEPVKVGHT-VGMDCQE-CTCEAATWTLTCRPKLCPLPPAC 731
                GC      +G  + V  + +  DC E C+C +++  LTC+   CP    C
Sbjct: 5171 VQDCGCTH----NGRYLPVNSSLLTSDCSERCSCSSSS-GLTCQAAGCPPGRVC 5219



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 42/165 (25%), Positives = 64/165 (38%), Gaps = 27/165 (16%)

Query: 282  YYALCSQDCQV---VRGVDSDCPSTTLPPAPATSPSISTSE---PVTELGCPNAVPPRKK 335
            +Y LC+  C +          CP          S  +   +   P+ + GC +     + 
Sbjct: 2738 HYELCADTCSLGCSALSAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGAYYEP 2797

Query: 336  GETWATPNC-SEATCEGNNVISLRPRTCP--RVEKPT-----CANGYPAVKVA------- 380
             +T    NC  + TC    V+  +  +C   +V +P+     C N  P   V        
Sbjct: 2798 EQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSCVNKDPCHGVTCRPQETC 2857

Query: 381  -DQDG---CCHHYQCQCVCSGWGDPHYITFDGTYYTFLDNCTYVL 421
             +Q G   C  +Y+  C    WGDPHY +FDG  + F   C YVL
Sbjct: 2858 KEQGGQGVCLPNYEATCWL--WGDPHYHSFDGRKFDFQGTCNYVL 2900



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 39/165 (23%), Positives = 60/165 (36%), Gaps = 27/165 (16%)

Query: 282  YYALCSQDCQV---VRGVDSDCPSTTLPPAPATSPSISTSE---PVTELGCPNAVPPRKK 335
            +Y LC+  C +          CP          S  +   +   P+ + GC +     + 
Sbjct: 3939 HYELCADTCSLGCSALSAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEP 3998

Query: 336  GETWATPNC-SEATCEGNNVISLRPRTCP--RVEKP----------------TCANGYPA 376
             +T    NC  + TC    V+  +  +C   +V +P                TC      
Sbjct: 3999 EQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETC 4058

Query: 377  VKVADQDGCCHHYQCQCVCSGWGDPHYITFDGTYYTFLDNCTYVL 421
             +   Q  C  +Y+  C    WGDPHY +FDG  + F   C YVL
Sbjct: 4059 KEQGGQGVCLPNYEATCWL--WGDPHYHSFDGRKFDFQGTCNYVL 4101



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 48/168 (28%), Positives = 63/168 (37%), Gaps = 35/168 (20%)

Query: 280  HCYYALCSQDCQVVRGVDSDCPSTTLPPAPATSP------------SISTSEPVTELGCP 327
            H +Y LC   C V       CPS + P    ++             S  T  PV + GC 
Sbjct: 4742 HSHYELCGDSCPV------SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCL 4795

Query: 328  NAVPPRKKGET-WATPNCSEATCE---GNNVISLRPRTCPRVEKPTCANGYPAVKVADQD 383
            +       GE  +  P C E  CE   G +V       C   E+    +G  A       
Sbjct: 4796 HDGRYYPLGEVFYPGPEC-ERRCECGPGGHVTCQEGAACGPHEECRLEDGVQA------- 4847

Query: 384  GCCHHYQC-QCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYG 430
              CH   C +C+ +G    HYIT DG  Y    +C+YVL Q   P  G
Sbjct: 4848 --CHATGCGRCLANG--GIHYITLDGRVYDLHGSCSYVLAQVCHPKPG 4891



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 27/83 (32%), Positives = 34/83 (40%), Gaps = 7/83 (8%)

Query: 344  CSEATCEGNNVISLRPRTCPRVEKPTC--ANGYPAVKVADQDG---CCHHYQCQCVCSGW 398
            C E +C+   V          V K  C      P     +Q G   C  +Y+  C    W
Sbjct: 1619 CQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWL--W 1676

Query: 399  GDPHYITFDGTYYTFLDNCTYVL 421
            GDPHY +FDG  + F   C YVL
Sbjct: 1677 GDPHYHSFDGRKFDFQGTCNYVL 1699



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 55/211 (26%), Positives = 75/211 (35%), Gaps = 39/211 (18%)

Query: 687  RCLGPHGEPVKVGHTVGMDCQECTCEAATWTLTCRPKLCPLPPACPLPGFVPVPAAPQAG 746
            RCL P G+   +   +      C    AT       +LCPL  +CP          P + 
Sbjct: 1095 RCLLP-GQSGPLCDALATYAAACQAAGATVHPWRSEELCPL--SCP----------PHSH 1141

Query: 747  QCCPQYSCACNTSRCPKPVGCPEGARAIPTYQEG------ACCPVQNCSWTVCSINGTLY 800
                 Y C  +    P P GC           EG      +C P+ +C    C   GT +
Sbjct: 1142 YEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCG---CVHQGTYH 1198

Query: 801  QPG-AVVSSSLCET-CRCELPGGPPSDAFVVSCETQICNTHCPVGFEYQEQSGQCCGTCV 858
             PG        C++ C C+  G       +VSCE+  C  H     E  + SG   G CV
Sbjct: 1199 PPGQTFYPGPGCDSLCHCQEGG-------LVSCESSSCGPH-----EACQPSGGSLG-CV 1245

Query: 859  QVACVT-NTSKSPAHLFYPGETWSDAGNHCV 888
             V   T   S  P +  + G  +   G  CV
Sbjct: 1246 AVGSSTCQASGDPHYTTFDGRRFDFMGT-CV 1275



 Score = 38.1 bits (87), Expect = 0.044
 Identities = 49/211 (23%), Positives = 66/211 (31%), Gaps = 64/211 (30%)

Query: 680  CVPTGCPRCLGPHGEPVKVGHTVGM----DCQECTCEA---------------------- 713
            C P GCP CL     P +     G          TC+A                      
Sbjct: 5028 CGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDK 5087

Query: 714  -------ATWTLTCRP-----------KLCPLPPACPLPGFVPVPAAPQAGQCCPQYSCA 755
                   A +T  C+              CPL   CP      +      G C       
Sbjct: 5088 AFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLH--CPAHSHYSICTRTCQGSCAALSGLT 5145

Query: 756  CNTSRCPKPVGCPEGARAIPTYQEGACCPVQNCSWTVCSINGTLYQP--GAVVSSSLCET 813
              T+RC +  GC    R +    +G C PVQ+C    C+ NG  Y P   ++++S   E 
Sbjct: 5146 GCTTRCFE--GCECDDRFL--LSQGVCIPVQDCG---CTHNGR-YLPVNSSLLTSDCSER 5197

Query: 814  C--------RCELPGGPPSDAFVVSCETQIC 836
            C         C+  G PP     V  E + C
Sbjct: 5198 CSCSSSSGLTCQAAGCPPGRVCEVKAEARNC 5228


>gi|239757282 PREDICTED: similar to Fc fragment of IgG binding
           protein [Homo sapiens]
          Length = 1403

 Score =  101 bits (251), Expect = 4e-21
 Identities = 124/527 (23%), Positives = 186/527 (35%), Gaps = 113/527 (21%)

Query: 300 CPSTTLPPAPATSPSISTSEPVTELGCP---------------------NAVPPRKKGET 338
           CP++   PAP T+P++     V    C                      N        E 
Sbjct: 365 CPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEF 424

Query: 339 WATPNCSE-ATC-EGNNVISLRPRTCPRVEK----PTCANGYPAVKVADQDGCCHHYQCQ 392
           WA   CS+   C  G   +   P +C   E     P+  +G   V  A+           
Sbjct: 425 WADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAE----------- 473

Query: 393 CVCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYG------HFRVLVDNYFCGAEDG 446
             C  WGDPHY+T DG  + F   C Y+L     P +G      +F V V N   G++  
Sbjct: 474 --CQAWGDPHYVTLDGHRFDFQGTCEYLLS---APCHGPPLGAENFTVTVANEHRGSQ-A 527

Query: 447 LSCPRSIILEYHQDRVVLTRKPVHGVMTNEIIFNNKVVSPGFRKNGIVVSRIGVKMYATI 506
           +S  RS+ L+ +   + L+ +    +  + +      V+  F+ + ++ + +        
Sbjct: 528 VSYTRSVTLQIYNHSLTLSARWPRKLQVDGVF-----VALPFQLDSLLHAHLSGADVVVT 582

Query: 507 PELGVQVMFSGLIF-SVEVPFSKFANNTEGQCXXXXXXXTTP------------------ 547
              G+ + F G  F  + VP + +A +  G C                            
Sbjct: 583 TTSGLSLAFDGDSFVRLRVP-AAYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQG 641

Query: 548 ---------PAPCLPSP--------ICQLILSK--VFEPCHTVIPPLLFYEGCVFDRCHM 588
                    P+PC P           C +I +      PCH ++PP  +++GC+ D C +
Sbjct: 642 CGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQV 701

Query: 589 T-DLDVVCSSLELYAALCASHDICI-DWRGRTGHMCPFTCPADKVYQPCGPSNPSYCYGN 646
                 +C ++  Y A C +    + +W  R    CP  CPA   Y+ CG S P  C   
Sbjct: 702 QGHPGGLCPAVATYVAACQAAGAQLGEW--RRPDFCPLQCPAHSHYELCGDSCPVSC--- 756

Query: 647 DSASLGALPEA--GPITEGCFCPEGMTLFSTSAQVCVPTGCPRCLGPHGEPVKVGHTV-- 702
              SL A PE       EGC C  G  L   S   CVP G   CL   G    +G     
Sbjct: 757 --PSLSA-PEGCESACREGCVCDAGFVL---SGDTCVPVGQCGCL-HDGRYYPLGEVFYP 809

Query: 703 GMDCQ-ECTCEAATWTLTCRPKLCPLPPACPLPGFVPVPAAPQAGQC 748
           G +C+  C C             C     C L   V    A   G+C
Sbjct: 810 GPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRC 856



 Score = 95.5 bits (236), Expect = 2e-19
 Identities = 63/174 (36%), Positives = 79/174 (45%), Gaps = 11/174 (6%)

Query: 565 FEPCHTVIPPLLFYEGCVFDRC-HMTDLDVVCSSLELYAALCASHDICI-DWRGRTGHMC 622
           F  CH  +PP  F++GCV D C    D D++C +L  Y A C +  + I DWR + G  C
Sbjct: 291 FTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVVIEDWRAQVG--C 348

Query: 623 PFTCPADKVYQPCGPSNPSYCYGNDSASLGALPEAGPITEGCFCPEGMTLFSTSAQVCVP 682
             TCP +  Y+ CGP  P+ C      +  A+ E GP  EGC C  G  L   SA  CVP
Sbjct: 349 EITCPENSHYEVCGPPCPASCPSPAPLTTPAVCE-GPCVEGCQCDAGFVL---SADRCVP 404

Query: 683 --TGCP-RCLGPHGEPVKVGHTVGMDCQECTCEAATWTLTCRPKLCPLPPACPL 733
              GC     G + E        G   Q C C     +L C P  C L   C L
Sbjct: 405 LNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGL 458



 Score = 67.0 bits (162), Expect = 9e-11
 Identities = 53/174 (30%), Positives = 75/174 (43%), Gaps = 21/174 (12%)

Query: 565  FEPCHTVIPPLLFYEGCVFDRC-HMTDLDVVCSSLELYAALCASHDICI-DWRGRTGHMC 622
            F  C  V+ P  ++  CV+D C    D   +C SL  Y A C +  + +  W  RT   C
Sbjct: 1060 FATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPW--RTDSFC 1117

Query: 623  PFTCPADKVYQPCGPSNPSYCYGNDSASLGALPEAGPITEGCFCPEGMTLFSTSAQVCVP 682
            P  CPA   Y  C  +    C G+ +A  G         EGC C +    F  S  VC+P
Sbjct: 1118 PLHCPAHSHYSICTRT----CQGSCAALSGLTGCTTRCFEGCECDD---RFLLSQGVCIP 1170

Query: 683  T---GCPRCLGPHGEPVKVGHT-VGMDCQE-CTCEAATWTLTCRPKLCPLPPAC 731
                GC      +G  + V  + +  DC E C+C +++  LTC+   CP    C
Sbjct: 1171 VQDCGCTH----NGRYLPVNSSLLTSDCSERCSCSSSS-GLTCQAAGCPPGRVC 1219



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 48/168 (28%), Positives = 63/168 (37%), Gaps = 35/168 (20%)

Query: 280 HCYYALCSQDCQVVRGVDSDCPSTTLPPAPATSP------------SISTSEPVTELGCP 327
           H +Y LC   C V       CPS + P    ++             S  T  PV + GC 
Sbjct: 742 HSHYELCGDSCPV------SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCL 795

Query: 328 NAVPPRKKGET-WATPNCSEATCE---GNNVISLRPRTCPRVEKPTCANGYPAVKVADQD 383
           +       GE  +  P C E  CE   G +V       C   E+    +G  A       
Sbjct: 796 HDGRYYPLGEVFYPGPEC-ERRCECGPGGHVTCQEGAACGPHEECRLEDGVQA------- 847

Query: 384 GCCHHYQC-QCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYG 430
             CH   C +C+ +G    HYIT DG  Y    +C+YVL Q   P  G
Sbjct: 848 --CHATGCGRCLANG--GIHYITLDGRVYDLHGSCSYVLAQVCHPKPG 891



 Score = 44.3 bits (103), Expect = 6e-04
 Identities = 30/99 (30%), Positives = 38/99 (38%), Gaps = 6/99 (6%)

Query: 324 LGCPNAVPPRKKGETWATPNCSEATCEGNNVISLRPRTCPR-VEKPTCANGYPAVKVADQ 382
           L C N   P+  G  W     +     G  +  L P   P      TC       +   Q
Sbjct: 8   LACSN---PQIPGTDWVDMEGAAMLYNGQPLKVLLPLLSPDPCHGVTCRPQETCKEQGGQ 64

Query: 383 DGCCHHYQCQCVCSGWGDPHYITFDGTYYTFLDNCTYVL 421
             C  +Y+  C    WGDPHY +FDG  + F   C YVL
Sbjct: 65  GVCLPNYEATCWL--WGDPHYHSFDGRKFDFQGTCNYVL 101



 Score = 38.1 bits (87), Expect = 0.044
 Identities = 49/211 (23%), Positives = 66/211 (31%), Gaps = 64/211 (30%)

Query: 680  CVPTGCPRCLGPHGEPVKVGHTVGM----DCQECTCEA---------------------- 713
            C P GCP CL     P +     G          TC+A                      
Sbjct: 1028 CGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDK 1087

Query: 714  -------ATWTLTCRP-----------KLCPLPPACPLPGFVPVPAAPQAGQCCPQYSCA 755
                   A +T  C+              CPL   CP      +      G C       
Sbjct: 1088 AFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLH--CPAHSHYSICTRTCQGSCAALSGLT 1145

Query: 756  CNTSRCPKPVGCPEGARAIPTYQEGACCPVQNCSWTVCSINGTLYQP--GAVVSSSLCET 813
              T+RC +  GC    R +    +G C PVQ+C    C+ NG  Y P   ++++S   E 
Sbjct: 1146 GCTTRCFE--GCECDDRFL--LSQGVCIPVQDCG---CTHNGR-YLPVNSSLLTSDCSER 1197

Query: 814  C--------RCELPGGPPSDAFVVSCETQIC 836
            C         C+  G PP     V  E + C
Sbjct: 1198 CSCSSSSGLTCQAAGCPPGRVCEVKAEARNC 1228


>gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens]
          Length = 1503

 Score =  100 bits (249), Expect = 7e-21
 Identities = 137/591 (23%), Positives = 199/591 (33%), Gaps = 119/591 (20%)

Query: 173  EGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCPVTSVTPYGTSPTNALYPSLSTSMVSA 232
            E  +C  Q +  P   C   +     C +  GCP + + P G            T   + 
Sbjct: 975  EVCICEPQPEGPPSLRCHRRQ-----CPSLVGCPPSQLLPPGPQHC------CPTCAEAL 1023

Query: 233  SVASTSVASSSVASSSVAYSTQTCFCNVADRLYPAGSTIYRHRDLAGHCYYALCSQDCQV 292
            S  S  +  S +A     Y   TC C                +DL   C +  C +    
Sbjct: 1024 SNCSEGLLGSELAPPDPCY---TCQC----------------QDLTWLCIHQACPE---- 1060

Query: 293  VRGVDSDCPSTTLPPAPATSPSISTSEPVTELGCPNAVPPRKKGETWATPNCSEATCEGN 352
                   CP +     P +   +  +   +   C +       GE W    C+  +C   
Sbjct: 1061 -----LSCPLSERHTPPGSCCPVCRAPTQS---CVHQGREVASGERWTVDTCTSCSCMAG 1112

Query: 353  NVISLRPRTCPRVEKPTCANGYPAVKVADQDGCCHHYQCQ-CVCSGWGDPHYITFDGTYY 411
             V     R  P    P  A   PA+       CC     +   C  +GDPHY TFDG   
Sbjct: 1113 TVRCQSQRCSPLSCGPDKA---PALSPGS---CCPRCLPRPASCMAFGDPHYRTFDGRLL 1166

Query: 412  TFLDNCTYVLVQQIVPVYGHFRVLVDNYFCGAEDGLSCPRSIILEYHQDRVVLTRKPVHG 471
             F  +C+YVL +      G F V V N   G        RS +    +  V+L    V  
Sbjct: 1167 HFQGSCSYVLAKDCHS--GDFSVHVTNDDRG--------RSGVAWTQEVAVLLGDMAVRL 1216

Query: 472  VMTNEIIFNNKVVSPGFRKNGIVVSRIGVKMYATIPELGVQVMFSGLI-FSVEVPFSKFA 530
            +    +  +   V+  F +  ++   +         + G+QV++ G     V VP S + 
Sbjct: 1217 LQDGAVTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGS-YQ 1275

Query: 531  NNTEGQCXXXXXXXTT----PPAPCLPSPI------------------------------ 556
              T G C             P    LPS                                
Sbjct: 1276 GRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPCRAA 1335

Query: 557  -----------CQLILSKVFEPCHTVIPPLLFYEGCVFDRCHM---TDLDV-VCSSLELY 601
                       C ++ S  F  CH V+PP  F+  CV+D C     +  D  +C +LE Y
Sbjct: 1336 GYRARREANARCGVLKSSPFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDALEAY 1395

Query: 602  AALCASHDICIDWRGRTGHMCPFTCPADK--VYQPCGPSNPSYCYGNDSASLGALPE--A 657
            A+ C    +   WRG T  +C   CP ++  V+  CGP  P  C+ N    LG L     
Sbjct: 1396 ASHCRQAGVTPTWRGPT--LCVVGCPLERGFVFDECGPPCPRTCF-NQHIPLGELAAHCV 1452

Query: 658  GPITEGCFCPEGMTLFSTSAQVCVPTGCPRCLGPHGEPVKVGHTVGMDCQE 708
             P   GC CP G  L    A    P  CP+ L    +P+    +   + QE
Sbjct: 1453 RPCVPGCQCPAG--LVEHEAHCIPPEACPQVLLTGDQPLGARPSPSREPQE 1501



 Score = 79.7 bits (195), Expect = 1e-14
 Identities = 112/443 (25%), Positives = 142/443 (32%), Gaps = 136/443 (30%)

Query: 596  SSLELYAALCASHDICIDWRGRTG--------HMCPFTCPADKVYQPCGPSNPSYCY-GN 646
            +S E + +  A+  +C+ W G            +CPF    D     C P      Y G 
Sbjct: 670  ASGERFPSPTAACHLCLCWEGSVSCEPKACAPALCPFPARGD-----CCPDCDGCEYLGE 724

Query: 647  DSASLGALPEAGPITEGCFCPEGMTLFSTSAQVCVPTGC-----------PRCLGP--HG 693
               S    P+       C C  G    +   + C P GC           P C G   HG
Sbjct: 725  SYLSNQEFPDPREPCNLCTCLGGFV--TCGRRPCEPPGCSHPLIPSGHCCPTCQGCRYHG 782

Query: 694  EPVKVGHTV----GMDCQECTCEAATWTLTCRPKLCPLPPACPLPG----FVPV------ 739
                 G T+       C  CTC+  +  + C+ K CP P  CP P     F PV      
Sbjct: 783  VTTASGETLPDPLDPTCSLCTCQEGS--MRCQKKPCP-PALCPHPSPGPCFCPVCHSCLS 839

Query: 740  -------------PAAP------QAGQC------CPQYSCACNTSR----CPKPVGC--- 767
                         PA        QAGQ       CP   C    +     CP+  GC   
Sbjct: 840  QGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQCPPLPCKLQVTERGSCCPRCRGCLAH 899

Query: 768  ----PEGARAIP--------TYQEGA---------------------CCPVQNCSWTVCS 794
                PEG+R +P           EG                      CCP   CS   C 
Sbjct: 900  GEEHPEGSRWVPPDSACSSCVCHEGVVTCARIQCISSCAQPRQGPHDCCP--QCS--DCE 955

Query: 795  INGTLYQPGAVVSSSL--CETCRCE-LPGGPPSDAFVVSCETQICNT--HCPVGFEYQEQ 849
              G  Y+PG         CE C CE  P GPPS    + C  + C +   CP        
Sbjct: 956  HEGRKYEPGESFQPGADPCEVCICEPQPEGPPS----LRCHRRQCPSLVGCPPSQLLPPG 1011

Query: 850  SGQCCGTCVQVACVTNTSKSPAHLFYPGETWSDAGNHCVTHQCEKHQDGLVVVTTKKACP 909
               CC TC +     +     + L  P        + C T QC+     L  +   +ACP
Sbjct: 1012 PQHCCPTCAEALSNCSEGLLGSELAPP--------DPCYTCQCQD----LTWLCIHQACP 1059

Query: 910  PLSCSLDEARMSKDGCCRFCPPP 932
             LSC L E       CC  C  P
Sbjct: 1060 ELSCPLSERHTPPGSCCPVCRAP 1082



 Score = 60.8 bits (146), Expect = 6e-09
 Identities = 91/375 (24%), Positives = 121/375 (32%), Gaps = 109/375 (29%)

Query: 636 GPSNPSYCYGN-DSASLGALPEAGPITEGCFCPEGMTLFSTSAQVCVPTG--CPRCL--- 689
           G S     YGN ++ S  A      +T    C           + C P G  CP C    
Sbjct: 137 GCSQNGQTYGNGETFSPDACTTCRCLTGAVQCQGPSCSELNCLESCTPPGECCPICCTEG 196

Query: 690 GPHGEPVKVGHTVGMDCQECTCEAATWTLTCRPKLCPLPPACPLPGFVPVPAAPQAGQCC 749
           G H E  +   T G  C+ C C      + CR + C            P PA P  G CC
Sbjct: 197 GSHWEHGQEWTTPGDPCRICRCLEGH--IQCRQRECA--------SLCPYPARPLPGTCC 246

Query: 750 P-------------------------QYSCACNTSRCPKPVGCPEGARAIPTYQEGACCP 784
           P                            CA  + +C +P+ CP      P    G CCP
Sbjct: 247 PVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQC-EPLPCPPVPCRHPGKIPGQCCP 305

Query: 785 VQNCSWTVCSINGTLYQPG---AVVSSSLCETCRCELPGGPPSDAFVVSCETQIC----- 836
           V  C    C   G  YQ      +    LC  C C+        A  VSCE Q C     
Sbjct: 306 V--CDG--CEYQGHQYQSQETFRLQERGLCVRCSCQ--------AGEVSCEEQECPVTPC 353

Query: 837 ------NTHCPV----GFEYQ-----EQSGQCCGTCV---------QVACVTNTSKSP-- 870
                    CP     G E+      E  G+ C  CV          V C     + P  
Sbjct: 354 ALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQ 413

Query: 871 ---------------AHLFYPGETWSDAGNHCVTHQCEKHQDGLVVVTTKKACPPLSCSL 915
                          + ++  G+ ++DA + C    C   QDG V  +    CPP +C+ 
Sbjct: 414 PPGACCPSCDSCTYHSQVYANGQNFTDADSPCHACHC---QDGTVTCSLVD-CPPTTCAR 469

Query: 916 DEARMSKDGCCRFCP 930
            ++   +  CC  CP
Sbjct: 470 PQSGPGQ--CCPRCP 482



 Score = 60.8 bits (146), Expect = 6e-09
 Identities = 104/463 (22%), Positives = 135/463 (29%), Gaps = 157/463 (33%)

Query: 545 TTPPAPCLPSPICQLILSKVF----------EPCHTVIPPLLFYEGCVFDRCHMTDLDVV 594
           T PP  C PS       S+V+           PCH                CH  D  V 
Sbjct: 412 TQPPGACCPSCDSCTYHSQVYANGQNFTDADSPCHA---------------CHCQDGTVT 456

Query: 595 CSSLELYAALCASHDICIDWRGRTGHMCPFTCPADKVYQPCGPSNPSYCYGNDSASLGAL 654
           CS ++     CA        +   G  CP  CP   + +       S+ +  D       
Sbjct: 457 CSLVDCPPTTCARP------QSGPGQCCP-RCPDCILEEEVFVDGESFSHPRDPC----- 504

Query: 655 PEAGPITEGCFCPEGMTLFSTSAQVCVPTGCPRCLGPHGEPVKVGHTVGMDCQECT---- 710
                  + C C EG          C P  CPR    H  P   G     DC  C     
Sbjct: 505 -------QECRCQEGHAH-------CQPRPCPRAPCAHPLP---GTCCPNDCSGCAFGGK 547

Query: 711 -----------------CEAATWTLTCRPKLC-PLPPACPLPGFVPVPAAPQAGQCCPQY 752
                            C   +  + C  + C PLP  CP P  +P       G+CCPQ 
Sbjct: 548 EYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLP--CPEPVLLP-------GECCPQ- 597

Query: 753 SCACNTSRCPKPVGCPEGARAIPTYQEGACCPVQNCSWTVCSINGTLYQPGAVVSSSLCE 812
                   CP P GCP    A   +QE    P   C   +C ++G+              
Sbjct: 598 --------CPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLC-LDGS-------------- 634

Query: 813 TCRCELPGGPPSDAFVVSCETQICNTHCPVGFEYQEQSGQCCGTCVQVACVTNTSKSPAH 872
                           VSC+       CP       + G CC +C    C+    +    
Sbjct: 635 ----------------VSCQ----RLPCPPAPCAHPRQGPCCPSC--DGCLYQGKE---- 668

Query: 873 LFYPGETWSDAGNHCVTHQCEKHQDGLVVVTTKKACPPLSCSLDEARMSKDGCCRFCPPP 932
            F  GE +      C  H C   +    V    KAC P  C       ++  CC  C   
Sbjct: 669 -FASGERFPSPTAAC--HLCLCWEGS--VSCEPKACAPALCPFP----ARGDCCPDC--- 716

Query: 933 PPPYQNQSTCAVYHRSLIIQQQGCSSSEPVRLAYCRG---NCG 972
                    C     S +  Q+     EP  L  C G    CG
Sbjct: 717 -------DGCEYLGESYLSNQEFPDPREPCNLCTCLGGFVTCG 752



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 77/285 (27%), Positives = 95/285 (33%), Gaps = 63/285 (22%)

Query: 685  CPRCLG--PHGEPVKVGHT-VGMD--CQECTCEAATWTLTCRPKLCPLPPACPLPGFVPV 739
            CPRC G   HGE    G   V  D  C  C C      +TC    C    A P  G  P 
Sbjct: 890  CPRCRGCLAHGEEHPEGSRWVPPDSACSSCVCHEGV--VTCARIQCISSCAQPRQG--PH 945

Query: 740  PAAPQAGQC-------------------CPQYSCA----------CNTSRCPKPVGCPEG 770
               PQ   C                   C    C           C+  +CP  VGCP  
Sbjct: 946  DCCPQCSDCEHEGRKYEPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPS 1005

Query: 771  ARAIPTYQEGACCPVQNCSWTVCSINGTLYQPGAVVSSSLCETCRCELPGGPPSDAFVVS 830
                P  Q   CCP    + + CS  G L     +     C TC+C+             
Sbjct: 1006 QLLPPGPQH--CCPTCAEALSNCS-EGLL--GSELAPPDPCYTCQCQ--------DLTWL 1052

Query: 831  CETQIC-NTHCPVGFEYQEQSGQCCGTCVQVACVTNTSKSPAHLFYPGETWSDAGNHCVT 889
            C  Q C    CP+  E     G CC  C      T +          GE W+   + C +
Sbjct: 1053 CIHQACPELSCPLS-ERHTPPGSCCPVC---RAPTQSCVHQGREVASGERWTV--DTCTS 1106

Query: 890  HQCEKHQDGLVVVTTKKACPPLSCSLDEA-RMSKDGCCRFCPPPP 933
              C     G V   +++ C PLSC  D+A  +S   CC  C P P
Sbjct: 1107 CSC---MAGTVRCQSQR-CSPLSCGPDKAPALSPGSCCPRCLPRP 1147



 Score = 53.9 bits (128), Expect = 8e-07
 Identities = 69/278 (24%), Positives = 92/278 (33%), Gaps = 57/278 (20%)

Query: 706 CQECTCEAATWTLTCRPKLCP------------LPPACPLPG--FVPVPAAPQAGQCCPQ 751
           C  C+C+A    ++C  + CP            L PAC L G  F         G+ C  
Sbjct: 331 CVRCSCQAGE--VSCEEQECPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTA 388

Query: 752 YSCACNTSRCPKPVGCPEGARAIPTYQEGACCPVQNCSWTVCSINGTLYQPGA--VVSSS 809
             C     +C   V CP      PT   GACCP    S   C+ +  +Y  G     + S
Sbjct: 389 CVCQDGVPKCGA-VLCPPAPCQHPTQPPGACCP----SCDSCTYHSQVYANGQNFTDADS 443

Query: 810 LCETCRCELPGGPPSDAFVVSCETQICNTHCPVGFEYQEQSGQCCGTCVQVACVTNTSKS 869
            C  C C+          +V C    C          Q   GQCC  C    C+      
Sbjct: 444 PCHACHCQ---DGTVTCSLVDCPPTTC-------ARPQSGPGQCCPRCPD--CILE---- 487

Query: 870 PAHLFYPGETWSDAGNHCVTHQCEKHQDGLVVVTTKKACPPLSCSLDEARMSKDGCCRFC 929
              +F  GE++S   + C   +C   Q+G         C P  C          G C  C
Sbjct: 488 -EEVFVDGESFSHPRDPCQECRC---QEG------HAHCQPRPCPRAPCAHPLPGTC--C 535

Query: 930 PPPPPPYQNQSTCAVYHRSLIIQQQGCSSSEPVRLAYC 967
           P       + S CA   +           S+P RL  C
Sbjct: 536 P------NDCSGCAFGGKEYPSGADFPHPSDPCRLCRC 567



 Score = 50.4 bits (119), Expect = 9e-06
 Identities = 59/245 (24%), Positives = 80/245 (32%), Gaps = 69/245 (28%)

Query: 664  CFCPEGMTLFSTSAQV-CVPTGCPRCLGPH------------GEPVKVGHTV--GMD-CQ 707
            C C EG+    T A++ C+ +      GPH            G   + G +   G D C+
Sbjct: 919  CVCHEGVV---TCARIQCISSCAQPRQGPHDCCPQCSDCEHEGRKYEPGESFQPGADPCE 975

Query: 708  ECTCEAATW---TLTCRPKLCPLPPACPLPGFVPVPAAPQAGQCCPQ------------- 751
             C CE       +L C  + CP    CP    +P    P    CCP              
Sbjct: 976  VCICEPQPEGPPSLRCHRRQCPSLVGCPPSQLLP----PGPQHCCPTCAEALSNCSEGLL 1031

Query: 752  ----------YSCACNT-------SRCPKPVGCPEGARAIPTYQEGACCPVQNCSWTVCS 794
                      Y+C C           CP+ + CP   R  P    G+CCPV       C 
Sbjct: 1032 GSELAPPDPCYTCQCQDLTWLCIHQACPE-LSCPLSERHTPP---GSCCPVCRAPTQSCV 1087

Query: 795  INGTLYQPGAVVSSSLCETCRCELPGGPPSDAFVVSCETQICN-THCPVGFEYQEQSGQC 853
              G     G   +   C +C C         A  V C++Q C+   C          G C
Sbjct: 1088 HQGREVASGERWTVDTCTSCSCM--------AGTVRCQSQRCSPLSCGPDKAPALSPGSC 1139

Query: 854  CGTCV 858
            C  C+
Sbjct: 1140 CPRCL 1144



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 62/227 (27%), Positives = 80/227 (35%), Gaps = 64/227 (28%)

Query: 753 SCACNTSRCPKPVGC----PEGARAIP------TYQEGA--CCP---VQNCSWTVCSING 797
           SC C+ +  P+  G     PEGAR  P        Q+GA  C P   + +C    CS NG
Sbjct: 86  SCECHPAS-PQCWGLGRAWPEGARWEPDACTACVCQDGAAHCGPQAHLPHCRG--CSQNG 142

Query: 798 TLYQPGAVVSSSLCETCRCELPGGPPSDAFVVSCETQICN-THCPVGFEYQEQSGQCCGT 856
             Y  G   S   C TCRC L G        V C+   C+  +C    E     G+CC  
Sbjct: 143 QTYGNGETFSPDACTTCRC-LTG-------AVQCQGPSCSELNC---LESCTPPGECCPI 191

Query: 857 CVQVACVTNTSKSPAHLFYPGETWSDAGNHCVTHQC-EKHQDGLVVVTTKKACPPLSCSL 915
           C    C    S      +  G+ W+  G+ C   +C E H               + C  
Sbjct: 192 C----CTEGGSH-----WEHGQEWTTPGDPCRICRCLEGH---------------IQCRQ 227

Query: 916 DEARMSKDGCCRFCPPPPPPYQNQSTCAVYHRSLIIQQQGCSSSEPV 962
            E       C   CP P  P     TC        +  +   S EPV
Sbjct: 228 RE-------CASLCPYPARPL--PGTCCPVCDGCFLNGREHRSGEPV 265


>gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo
            sapiens]
          Length = 2134

 Score = 90.1 bits (222), Expect = 1e-17
 Identities = 142/654 (21%), Positives = 231/654 (35%), Gaps = 125/654 (19%)

Query: 143  EEITRLQCRAESHPEVNIEHLGQVVQ-CSREEGLVCRNQ----DQQGPFKMCLNYEVRVL 197
            EE  +  C  E+  +     LG  V+ C+ +E  +   +    +   P  +   Y V+  
Sbjct: 1072 EECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHSCPSGLVFKYNVKAC 1131

Query: 198  ------CCETPRGCPVTSVTPYGTSPTNALYPSLSTSMVSASVASTSVASSSVASSSVAY 251
                    E  R C V  V   G +  +A+Y +   + V  S     +    +    + +
Sbjct: 1132 NSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIH 1191

Query: 252  -STQTCFCNVADRL--YPAGSTIYRHRDLAGHCYYALCSQDCQVVRGVDSDCPSTTLPPA 308
                 C C     L   P   T+   ++ +G   Y  CS D +  R  +  C +  +P  
Sbjct: 1192 IDDNKCVCRDGILLCQIPIDLTL---QNCSGGAEYVDCS-DPKAQRRTNRTCSTRNIPVF 1247

Query: 309  PATSPSISTSEPVTELGCPNAVPPRKKGETWATPNCSEATCEGN-----NVISLRPRTCP 363
                P            CP  +    KG     PN    +  G      +V S+    C 
Sbjct: 1248 DENLPC------KRGCFCPEGMVRNSKG-ICVFPNDCPCSFGGREYDEGSVTSVGCNEC- 1299

Query: 364  RVEKPTCANGYPAVKVADQDGCCHHYQCQCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQ 423
                 TC  G            C   +CQ +C  +G+ H  TFDG  Y+F   C Y  ++
Sbjct: 1300 -----TCIKG---------SWSCTQNECQTICHIYGEGHVRTFDGKSYSFDGLCQYSFLE 1345

Query: 424  QIV-PVYGHFRVLVDNYFCGAEDGLSCPRSIILEYHQDRVVLTRKPVHGVMTNE---IIF 479
                   G FR+L ++  C  EDGL+C R II+ +    +VL    V  V + E      
Sbjct: 1346 DYCGHENGTFRILTESVPC-CEDGLTCSRKIIVAFQDQNIVLQDGKVTAVKSTESKKCEL 1404

Query: 480  NNKVVS---PGFR-----KNGIVV-----SRIGVKMYATIPELGVQVM------------ 514
            N    S    G       +NGI+V     +R+ V +    P    +V             
Sbjct: 1405 NANAYSIHTVGLYLILKFQNGIIVIWDKNTRLSVIL---DPNWNGKVCGLCGNNNGDLKD 1461

Query: 515  -FSGLIFSVEVPFSKFANN--TEGQCXXXXXXXTTPPAPCLPSPI--------CQLILSK 563
             F+    SV     +F N+  T  +C            PC  +P         C+++   
Sbjct: 1462 DFTTRYSSVASGALEFGNSWKTSQEC----SDTVAQTFPCDSNPYCKAWAVRKCEILRDS 1517

Query: 564  VFEPCHTVIPPLLFYEGCVFDRCHMTDLD----VVCSSLELYAALCASHDICIDWRGRTG 619
             F  CH  + P  +++ C+ + C   D++      C+++ +YA  C++  +C+ W  R  
Sbjct: 1518 TFRDCHNKVDPSAYHDVCIEEAC-ACDMEGKYLGFCTAVAMYAEACSAVGVCVSW--RKP 1574

Query: 620  HMCPFTCPADKV-------YQPCGPSNPSYC----YGNDSASLGALPEAGPITEGCF--C 666
            ++CP  C            Y+PCG      C     G   +SL          EGC+  C
Sbjct: 1575 NLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQKFSSL---------LEGCYAKC 1625

Query: 667  PEGMTLFSTSAQVCVPTGCPRCLGPHGEPVKVGHTVGMDCQECTCEAATWTLTC 720
            P+       +   CV      C   + + +  G  +  +C   TC      L C
Sbjct: 1626 PDSAPYLDENTMKCVSLSECSCF--YNDVIPAGGVIEDNCGR-TCYCIAGQLEC 1676



 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 52/177 (29%), Positives = 71/177 (40%), Gaps = 17/177 (9%)

Query: 557 CQLILSKVFEPCHTVIPPLLFYEG-CVFDRCHMTDLDVVCSSLELYAALCASHD--ICID 613
           C  I+   FE C  V      Y+  C+ + C   D    C +    + LCAS        
Sbjct: 689 CNKIIGTYFEKCGKVAALSNDYKMICIDEYCQTRDKTSTCDTYSELSRLCASDGPGTFES 748

Query: 614 WRGRTGHMCPFT-CPADKVYQPCGPSNPSYCYGNDSASLGALPEAGPITEGCFCPEGMTL 672
           WR  +  +C    CP   +Y+ CGPSNP+ C      S  A  +      GC CPEG  L
Sbjct: 749 WRSDSDVVCETQRCPEQHIYKECGPSNPATC------SNVAPFQDSECVSGCTCPEGYLL 802

Query: 673 --FSTSAQVCVPTGCP-RCLGPHGEPVKVGHTVGMDCQECTCEAATWTLTCRPKLCP 726
                  +  +   CP    G   +P +V    G    +CTC+ A W  +C   LCP
Sbjct: 803 DDIGEKGKCVLKAECPCESSGTVYQPGEVRE--GPCGSQCTCQDAKW--SCTEALCP 855



 Score = 39.7 bits (91), Expect = 0.015
 Identities = 29/102 (28%), Positives = 37/102 (36%), Gaps = 17/102 (16%)

Query: 747 QCCPQYSCACNT------SRCPKPVGCPEGARAIPTYQEGACCPVQNCSWTVCSINGTLY 800
           +C P     C+       S C     CPEG       ++G C     C    C  +GT+Y
Sbjct: 770 ECGPSNPATCSNVAPFQDSECVSGCTCPEGYLLDDIGEKGKCVLKAECP---CESSGTVY 826

Query: 801 QPGAVVSSSLCETCRCELPGGPPSDAFVVSCETQICNTHCPV 842
           QPG V        C C+       DA   SC   +C   C V
Sbjct: 827 QPGEVREGPCGSQCTCQ-------DA-KWSCTEALCPGRCKV 860



 Score = 30.8 bits (68), Expect = 7.1
 Identities = 16/38 (42%), Positives = 22/38 (57%), Gaps = 1/38 (2%)

Query: 46   VPTTSTTSAPTTSTTSGPGTTPSPVPTTSTT-PVSKTS 82
            +P  +T+S+ TT TT GP T P     T T+ P+  TS
Sbjct: 1716 IPAITTSSSETTGTTLGPLTEPFTTGITETSVPIISTS 1753


>gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo
            sapiens]
          Length = 2134

 Score = 90.1 bits (222), Expect = 1e-17
 Identities = 142/654 (21%), Positives = 231/654 (35%), Gaps = 125/654 (19%)

Query: 143  EEITRLQCRAESHPEVNIEHLGQVVQ-CSREEGLVCRNQ----DQQGPFKMCLNYEVRVL 197
            EE  +  C  E+  +     LG  V+ C+ +E  +   +    +   P  +   Y V+  
Sbjct: 1072 EECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHSCPSGLVFKYNVKAC 1131

Query: 198  ------CCETPRGCPVTSVTPYGTSPTNALYPSLSTSMVSASVASTSVASSSVASSSVAY 251
                    E  R C V  V   G +  +A+Y +   + V  S     +    +    + +
Sbjct: 1132 NSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIH 1191

Query: 252  -STQTCFCNVADRL--YPAGSTIYRHRDLAGHCYYALCSQDCQVVRGVDSDCPSTTLPPA 308
                 C C     L   P   T+   ++ +G   Y  CS D +  R  +  C +  +P  
Sbjct: 1192 IDDNKCVCRDGILLCQIPIDLTL---QNCSGGAEYVDCS-DPKAQRRTNRTCSTRNIPVF 1247

Query: 309  PATSPSISTSEPVTELGCPNAVPPRKKGETWATPNCSEATCEGN-----NVISLRPRTCP 363
                P            CP  +    KG     PN    +  G      +V S+    C 
Sbjct: 1248 DENLPC------KRGCFCPEGMVRNSKG-ICVFPNDCPCSFGGREYDEGSVTSVGCNEC- 1299

Query: 364  RVEKPTCANGYPAVKVADQDGCCHHYQCQCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQ 423
                 TC  G            C   +CQ +C  +G+ H  TFDG  Y+F   C Y  ++
Sbjct: 1300 -----TCIKG---------SWSCTQNECQTICHIYGEGHVRTFDGKSYSFDGLCQYSFLE 1345

Query: 424  QIV-PVYGHFRVLVDNYFCGAEDGLSCPRSIILEYHQDRVVLTRKPVHGVMTNE---IIF 479
                   G FR+L ++  C  EDGL+C R II+ +    +VL    V  V + E      
Sbjct: 1346 DYCGHENGTFRILTESVPC-CEDGLTCSRKIIVAFQDQNIVLQDGKVTAVKSTESKKCEL 1404

Query: 480  NNKVVS---PGFR-----KNGIVV-----SRIGVKMYATIPELGVQVM------------ 514
            N    S    G       +NGI+V     +R+ V +    P    +V             
Sbjct: 1405 NANAYSIHTVGLYLILKFQNGIIVIWDKNTRLSVIL---DPNWNGKVCGLCGNNNGDLKD 1461

Query: 515  -FSGLIFSVEVPFSKFANN--TEGQCXXXXXXXTTPPAPCLPSPI--------CQLILSK 563
             F+    SV     +F N+  T  +C            PC  +P         C+++   
Sbjct: 1462 DFTTRYSSVASGALEFGNSWKTSQEC----SDTVAQTFPCDSNPYCKAWAVRKCEILRDS 1517

Query: 564  VFEPCHTVIPPLLFYEGCVFDRCHMTDLD----VVCSSLELYAALCASHDICIDWRGRTG 619
             F  CH  + P  +++ C+ + C   D++      C+++ +YA  C++  +C+ W  R  
Sbjct: 1518 TFRDCHNKVDPSAYHDVCIEEAC-ACDMEGKYLGFCTAVAMYAEACSAVGVCVSW--RKP 1574

Query: 620  HMCPFTCPADKV-------YQPCGPSNPSYC----YGNDSASLGALPEAGPITEGCF--C 666
            ++CP  C            Y+PCG      C     G   +SL          EGC+  C
Sbjct: 1575 NLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQKFSSL---------LEGCYAKC 1625

Query: 667  PEGMTLFSTSAQVCVPTGCPRCLGPHGEPVKVGHTVGMDCQECTCEAATWTLTC 720
            P+       +   CV      C   + + +  G  +  +C   TC      L C
Sbjct: 1626 PDSAPYLDENTMKCVSLSECSCF--YNDVIPAGGVIEDNCGR-TCYCIAGQLEC 1676



 Score = 64.7 bits (156), Expect = 4e-10
 Identities = 52/177 (29%), Positives = 71/177 (40%), Gaps = 17/177 (9%)

Query: 557 CQLILSKVFEPCHTVIPPLLFYEG-CVFDRCHMTDLDVVCSSLELYAALCASHD--ICID 613
           C  I+   FE C  V      Y+  C+ + C   D    C +    + LCAS        
Sbjct: 689 CNKIIGTYFEKCGKVAALSNDYKMICIDEYCQTRDKTSTCDTYSELSRLCASDGPGTFES 748

Query: 614 WRGRTGHMCPFT-CPADKVYQPCGPSNPSYCYGNDSASLGALPEAGPITEGCFCPEGMTL 672
           WR  +  +C    CP   +Y+ CGPSNP+ C      S  A  +      GC CPEG  L
Sbjct: 749 WRSDSDVVCGTQRCPEQHIYKECGPSNPATC------SNVAPFQDSECVSGCTCPEGYLL 802

Query: 673 --FSTSAQVCVPTGCP-RCLGPHGEPVKVGHTVGMDCQECTCEAATWTLTCRPKLCP 726
                  +  +   CP    G   +P +V    G    +CTC+ A W  +C   LCP
Sbjct: 803 DDIGEKGKCVLKAECPCESSGTVYQPGEVRE--GPCGSQCTCQDAKW--SCTEALCP 855



 Score = 39.7 bits (91), Expect = 0.015
 Identities = 29/102 (28%), Positives = 37/102 (36%), Gaps = 17/102 (16%)

Query: 747 QCCPQYSCACNT------SRCPKPVGCPEGARAIPTYQEGACCPVQNCSWTVCSINGTLY 800
           +C P     C+       S C     CPEG       ++G C     C    C  +GT+Y
Sbjct: 770 ECGPSNPATCSNVAPFQDSECVSGCTCPEGYLLDDIGEKGKCVLKAECP---CESSGTVY 826

Query: 801 QPGAVVSSSLCETCRCELPGGPPSDAFVVSCETQICNTHCPV 842
           QPG V        C C+       DA   SC   +C   C V
Sbjct: 827 QPGEVREGPCGSQCTCQ-------DA-KWSCTEALCPGRCKV 860



 Score = 30.8 bits (68), Expect = 7.1
 Identities = 16/38 (42%), Positives = 22/38 (57%), Gaps = 1/38 (2%)

Query: 46   VPTTSTTSAPTTSTTSGPGTTPSPVPTTSTT-PVSKTS 82
            +P  +T+S+ TT TT GP T P     T T+ P+  TS
Sbjct: 1716 IPAITTSSSETTGTTLGPLTEPFTTGITETSVPIISTS 1753


>gi|151301154 mucin 6, gastric [Homo sapiens]
          Length = 2439

 Score = 82.8 bits (203), Expect = 2e-15
 Identities = 86/354 (24%), Positives = 132/354 (37%), Gaps = 46/354 (12%)

Query: 385  CCHHYQCQCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGH---FRVLVDNYFC 441
            C     C   C+ +G+ H ITFDG  + F  NC Y+L   +  V      F++L +N  C
Sbjct: 858  CQQGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPTFKILTENVIC 917

Query: 442  GAEDGLSCPRSIILEYHQDRVVL-------TRKPVH---GVMTNEIIFNNKVVSPGFRKN 491
            G   G++C R+I +      VVL       T +  H   GV    +     +  PG    
Sbjct: 918  G-NSGVTCSRAIKIFLGGLSVVLADRNYTVTGEEPHVQLGVTPGALSLVVDISIPGRYNL 976

Query: 492  GIVVSR-----IGVKMYATIPELGVQVMFSGLIFSVEVPFSKFANNTEGQCXXXXXXX-- 544
             ++ +R     I +   +  P  G+   F+G +       S++  ++E +          
Sbjct: 977  TLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSWKESPL 1036

Query: 545  ----TTPPAPCLPSPI--------CQLILSKVFEPCHTVIPPLLFYEGCVFDRCHMT--- 589
                +    PC  +          C +I S+ F  CH+ +  L +YE CV D C      
Sbjct: 1037 CGDVSFVTDPCSLNAFRRSWAERKCSVINSQTFATCHSKVYHLPYYEACVRDACGCDSGG 1096

Query: 590  DLDVVCSSLELYAALCASHDICIDWRGRTGHMCPFTC--------PADKVYQPCGPSNPS 641
            D + +C ++  YA  C    +C+DW  RT   CP  C             YQ    +N +
Sbjct: 1097 DCECLCDAVAAYAQACLDKGVCVDW--RTPAFCPIYCGFYNTHTQDGHGEYQYTQEANCT 1154

Query: 642  YCYGNDSASLGALPEAGPITEGCFCPEGMTLFSTSAQVCVPTGCPRCLGPHGEP 695
            + Y             G   EGC+       F     VCVP   P    P   P
Sbjct: 1155 WHYQPCLCPSQPQSVPGSNIEGCYNCSQDEYFDHEEGVCVPCMPPTTPQPPTTP 1208



 Score = 76.3 bits (186), Expect = 1e-13
 Identities = 109/497 (21%), Positives = 171/497 (34%), Gaps = 99/497 (19%)

Query: 386 CHHYQCQCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQQI-VPVYGHFRVLVDNYFCGAE 444
           C    C   CS  G     TFD   Y F   CTY+L+Q   +P  G    + D    G  
Sbjct: 388 CTERPCPGHCSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYDK--SGVS 445

Query: 445 DGLSCPRSIILEYHQDRVVLTRKPVHGVMTNEIIFNNKVVSPGFRKNGIVVSRIGVKMYA 504
              +   +++    QD++V+++  V   +TN    N +     ++   I V R       
Sbjct: 446 HSETSLVAVVYLSRQDKIVISQDEV---VTN----NGEAKWLPYKTRNITVFRQTSTHLQ 498

Query: 505 TIPELGVQVMFS-GLIFSVEVPFS-KFANNTEGQCXXXXXXXTTP--------------- 547
                G++++     IF   V    +F   T G C       T                 
Sbjct: 499 MATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTASLF 558

Query: 548 ---------PA-------PCLPSPI--------CQLIL--SKVFEPCHTVIPPLLFYEGC 581
                    PA       PC  S +        C ++L    VFE CH  + P  FY+ C
Sbjct: 559 VDSWRAGNCPAALERETDPCSMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRC 618

Query: 582 VFDRCHMTD-LDVVCSSLELYAALCASHDICI-DWRGRTGHMCPFTCPADKVYQPCGPSN 639
           V+  C+  +    +C++L  Y   C+   + +  WR    + C   C  +  +     + 
Sbjct: 619 VYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDN-CTIPCTGNTTFSYNSQAC 677

Query: 640 PSYCYGNDSASLGALPEAGPITEGCFCPEGMTLFSTSAQVCVPTGCPRCLGPHGEPVKVG 699
              C      +      A P+ +GC CP+G T  +   +      CP  L  +   +   
Sbjct: 678 ERTCLSLSDRATECHHSAVPV-DGCNCPDG-TYLNQKGECVRKAQCPCILEGYKFILAEQ 735

Query: 700 HTVGMDCQECTCEAATWTLTC--RPKLCPLPPACPLPGFVPVPAAPQAGQCCPQYS---- 753
            TV       TC      L+C  RP++           F+    AP+  + C Q S    
Sbjct: 736 STV---INGITCHCINGRLSCPQRPQM-----------FLASCQAPKTFKSCSQSSENKF 781

Query: 754 --------------CACNTSRCPKPVGCPEGARAIPTYQEGACCPVQNCSWTVCSINGTL 799
                          AC  ++C     C EG   +    +G C P + C    C  +G  
Sbjct: 782 GAACAPTCQMLATGVACVPTKCEPGCVCAEG---LYENADGQCVPPEECP---CEFSGVS 835

Query: 800 YQPGAVVSSSLCETCRC 816
           Y  GA + +  C TC C
Sbjct: 836 YPGGAELHTD-CRTCSC 851



 Score = 72.8 bits (177), Expect = 2e-12
 Identities = 99/388 (25%), Positives = 140/388 (36%), Gaps = 78/388 (20%)

Query: 395 CSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVLVDNYFCGAEDGLSCPRSII 454
           CS WG  H+ TFD   Y F   C Y+        +  F V +     G +  +S    II
Sbjct: 45  CSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRR---GPDGSIS---RII 98

Query: 455 LEYHQDRVVLTRKPVHGVMTNEIIFNNKVVSPGFRKNGIVVSRIG--VKMYATIPELGVQ 512
           +E     V ++   +        + +  V+S  +  NG+ ++  G  V++ A   EL ++
Sbjct: 99  VELGASVVTVSEAIIS-------VKDIGVISLPYTSNGLQITPFGQSVRLVAKQLELELE 151

Query: 513 VMF---SGLIFSVEVPFSKFANNTEGQCXXXXXXXTT----------------------- 546
           V++   S L+  VE    K+     G C       T                        
Sbjct: 152 VVWGPDSHLMVLVE---RKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEPHKFAALQKLDD 208

Query: 547 PPAPC----LPSP---------ICQLILSKVFEPCHTVIPPLLFYEGCVFDRCHMTD--- 590
           P   C    +PS          IC  +L+ V   C     P  F   C  D         
Sbjct: 209 PGEICTFQDIPSTHVRQAQHARICTQLLTLVAPECSVSKEP--FVLSCQADVAAAPQPGP 266

Query: 591 LDVVCSSLELYAALCASHDICIDWRGRTGHMCPF-TCPADKVYQPCGPSNPSYCYGNDSA 649
            +  C++L  Y+  C+     +  R R+  +C    CPA++VYQ CG +    C     +
Sbjct: 267 QNSSCATLSEYSRQCSMVGQPVR-RWRSPGLCSVGQCPANQVYQECGSACVKTCSNPQHS 325

Query: 650 SLGALPEAGPITEGCFCPEGMTLFSTSAQ-VCVP-TGCPRCLGPHGEPVKVGHTVGMDCQ 707
                  +   T GCFCPEG  L   S    CVP T CP  L  HG     G      CQ
Sbjct: 326 C------SSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVL--HGAMYAPGEVTIAACQ 377

Query: 708 ECTCEAATWTLTCRPKLCPLPPACPLPG 735
            C C    W  T R    P P  C L G
Sbjct: 378 TCRCTLGRWVCTER----PCPGHCSLEG 401



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 32/97 (32%), Positives = 41/97 (42%), Gaps = 19/97 (19%)

Query: 734 PGFVPVPAAP------QAGQCC------PQYSCACNTSRCPKPVGCPEGARAIPTYQEGA 781
           PG   V   P      + G  C      PQ+SC+   S C     CPEG           
Sbjct: 294 PGLCSVGQCPANQVYQECGSACVKTCSNPQHSCS---SSCTFGCFCPEGTVLNDLSNNHT 350

Query: 782 CCPVQNCSWTVCSINGTLYQPGAVVSSSLCETCRCEL 818
           C PV  C    C ++G +Y PG V  ++ C+TCRC L
Sbjct: 351 CVPVTQCP---CVLHGAMYAPGEVTIAA-CQTCRCTL 383



 Score = 37.4 bits (85), Expect = 0.076
 Identities = 27/81 (33%), Positives = 39/81 (48%), Gaps = 8/81 (9%)

Query: 49   TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTST---SHLSVSKTTHSQPV----TSDC 101
            TS+T  P  ++TS    TP+   T + TPV+ T++   S L    TTHS P      S  
Sbjct: 1753 TSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISST 1812

Query: 102  HPLCAWTKWFDVDFPSPG-PH 121
             P+ A +      +P+P  PH
Sbjct: 1813 GPVTATSFQTTTTYPTPSHPH 1833



 Score = 37.0 bits (84), Expect = 0.099
 Identities = 23/82 (28%), Positives = 40/82 (48%), Gaps = 7/82 (8%)

Query: 930  PPPPPPYQNQSTCAVYHRSLIIQQQGCSSSEPVRLAYCRGNCGDSSSMYSLEGNTVEHRC 989
            P P  P      C+V  +   I  +GC ++  V +  C G C  ++S +++    V+ RC
Sbjct: 2341 PTPTSP----GVCSVREQQEEITFKGCMAN--VTVTRCEGACISAAS-FNIITQQVDARC 2393

Query: 990  QCCQELRTSLRNVTLHCTDGSS 1011
             CC+ L +  + + L C D S+
Sbjct: 2394 SCCRPLHSYEQQLELPCPDPST 2415



 Score = 36.2 bits (82), Expect = 0.17
 Identities = 26/77 (33%), Positives = 35/77 (45%), Gaps = 7/77 (9%)

Query: 49   TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKT---STSHLSVSKTTHSQPV----TSDC 101
            TS+T  P  + TS    TP    T + TPV+ T   S+S L    TTHS P      S  
Sbjct: 1922 TSSTHHPEVTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSST 1981

Query: 102  HPLCAWTKWFDVDFPSP 118
             P+ A +      +P+P
Sbjct: 1982 GPMTATSFQTTTTYPTP 1998



 Score = 35.8 bits (81), Expect = 0.22
 Identities = 30/101 (29%), Positives = 45/101 (44%), Gaps = 15/101 (14%)

Query: 25   HNLCSYNQNNLCLYSQHNLCPVPTTSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTS 84
            H+  S N+    L+S         TS+T  P  + TS    TP+P  T + TPV+ T+++
Sbjct: 1513 HSSFSTNKTPTSLHSH--------TSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSA 1564

Query: 85   HLSVSK---TTHSQPV----TSDCHPLCAWTKWFDVDFPSP 118
              S      TTHS P      S   P+ A +      +P+P
Sbjct: 1565 TSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTP 1605



 Score = 35.4 bits (80), Expect = 0.29
 Identities = 38/131 (29%), Positives = 54/131 (41%), Gaps = 29/131 (22%)

Query: 1    HNLCSYNQHNLWSWNY------SQPCSHRQHNL-----CSYNQ-----NNLCLYSQHNLC 44
            H    Y Q    +W+Y      SQP S    N+     CS ++       +C+       
Sbjct: 1142 HGEYQYTQEANCTWHYQPCLCPSQPQSVPGSNIEGCYNCSQDEYFDHEEGVCVPCMPPTT 1201

Query: 45   PVPTTS-----TTSAPT-------TSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTT 92
            P P T+     T S PT       TSTT G  ++  P P+++ TP S T T  L  + T+
Sbjct: 1202 PQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLPATLTS 1261

Query: 93   HSQPVTSDCHP 103
             S+P  S   P
Sbjct: 1262 -SKPTASSGEP 1271



 Score = 34.7 bits (78), Expect = 0.49
 Identities = 28/100 (28%), Positives = 43/100 (43%), Gaps = 9/100 (9%)

Query: 9    HNLWSWNYSQPCSHRQHNLCSYNQNNLCLYSQHNLCPVPTTSTTSAPTTSTTSGPGTTPS 68
            H+ +S N + P S   H   +++   +   S   + P PT++ T  P   T S   + P 
Sbjct: 1513 HSSFSTNKT-PTSLHSHTSSTHHPE-VTPTSTTTITPNPTSTRTRTPVAHTNSATSSRPP 1570

Query: 69   PV-----PTTSTTPVSKTSTSHLSVSKTTHSQPVTSDCHP 103
            P      P T ++P S T     +  KTT + P  S  HP
Sbjct: 1571 PPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPS--HP 1608



 Score = 34.7 bits (78), Expect = 0.49
 Identities = 26/61 (42%), Positives = 32/61 (52%), Gaps = 7/61 (11%)

Query: 39   SQHNLCPVPTTSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVT 98
            S  N+ P PT ST + P T TTSG   + S   T      +KTSTS  S + +TH   VT
Sbjct: 1710 STTNITPNPT-STGTPPMTVTTSGTSQSRSSFST------AKTSTSLHSHTSSTHHPEVT 1762

Query: 99   S 99
            S
Sbjct: 1763 S 1763



 Score = 34.3 bits (77), Expect = 0.64
 Identities = 71/304 (23%), Positives = 107/304 (35%), Gaps = 42/304 (13%)

Query: 39   SQHNLCPVPTTSTTSAPTTSTTSGPGTT-PSPV----PTTSTTPVSKTSTSHLSVSKTTH 93
            S  N+ P  T++ T  P   TTS   +  P+P     P T ++P S T     +  +TT 
Sbjct: 1934 STTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTATSFQTTT 1993

Query: 94   SQPVTSDCHP---LCAWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEI----T 146
            + P  S  HP   L      F     +P  H     T+  +  S   I   P       T
Sbjct: 1994 TYPTPS--HPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSA-SIHSTPTGTVPPPT 2050

Query: 147  RLQCRAESH--PEVNIEHLGQVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRG 204
             L+    +H  P + +   G     S        +        +  N   R      P  
Sbjct: 2051 TLKATGSTHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSR------PPS 2104

Query: 205  CPVTSVTPY---GTSP---TNALYPSLSTSMVSASVASTSVASSSVASSSVAYSTQTCFC 258
             P+T+  P+    T+P   TN L  S S S  + S  S+ V SS  +  + + S  T   
Sbjct: 2105 SPITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSS 2164

Query: 259  NVADRLYPAGSTIYRHRDLAGHCYYALCSQDCQVVRGVDSDCPSTTLPPAPATSPSISTS 318
             V+  ++    +   H  L+ H   A  S              S   P +PA S +I  +
Sbjct: 2165 FVSAPVHSTTLSSGSHSSLSTHPTTASVS-------------ASPLFPSSPAASTTIRAT 2211

Query: 319  EPVT 322
             P T
Sbjct: 2212 LPHT 2215



 Score = 32.0 bits (71), Expect = 3.2
 Identities = 30/113 (26%), Positives = 42/113 (37%), Gaps = 15/113 (13%)

Query: 625 TCPADKVYQPCGPSNPSYCYGNDSASLGALPEAG------PITEGCFCPEGMTLFSTSAQ 678
           +C A K ++ C  S+ +  +G   A    +   G          GC C EG  L+  +  
Sbjct: 763 SCQAPKTFKSCSQSSENK-FGAACAPTCQMLATGVACVPTKCEPGCVCAEG--LYENADG 819

Query: 679 VCVPTG-CPRCLGPHGEPVKVGHTVGMDCQECTCEAATWTL---TCRPKLCPL 727
            CVP   CP      G     G  +  DC+ C+C    W     T  P  C L
Sbjct: 820 QCVPPEECPCEFS--GVSYPGGAELHTDCRTCSCSRGRWACQQGTHCPSTCTL 870



 Score = 32.0 bits (71), Expect = 3.2
 Identities = 30/93 (32%), Positives = 37/93 (39%), Gaps = 17/93 (18%)

Query: 46   VPTTSTTS--------------APTTSTTSGPGTTP--SPVPTTSTTPVSKTSTSHLSVS 89
            V +TSTTS              A TTS TS    TP  +  P T TTP+S T     +  
Sbjct: 1761 VTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTATSF 1820

Query: 90   KTTHSQPVTSDCH-PLCAWTKWFDVDFPSPGPH 121
            +TT + P  S  H  L      F     +P  H
Sbjct: 1821 QTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTH 1853



 Score = 30.8 bits (68), Expect = 7.1
 Identities = 24/89 (26%), Positives = 32/89 (35%), Gaps = 10/89 (11%)

Query: 45   PVPTTSTTSA----------PTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHS 94
            P P TS TS           P T+ T   G  P+P  TT  T       +  + ++TT +
Sbjct: 1332 PTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGPTTPQPGQPTRPTATETTQT 1391

Query: 95   QPVTSDCHPLCAWTKWFDVDFPSPGPHGG 123
            +  T    P    T        SP P  G
Sbjct: 1392 RTTTEYTTPQTPHTTHSPPTAGSPVPSTG 1420



 Score = 30.8 bits (68), Expect = 7.1
 Identities = 19/53 (35%), Positives = 26/53 (49%), Gaps = 1/53 (1%)

Query: 51   TTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPV-TSDCH 102
            T + P  +T    G+T +  P T TT  +  S S  S +KT+ S P  TS  H
Sbjct: 1874 TGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTH 1926



 Score = 30.8 bits (68), Expect = 7.1
 Identities = 23/60 (38%), Positives = 29/60 (48%), Gaps = 12/60 (20%)

Query: 45   PVPTT------STTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVT 98
            P PTT      + T+ P T TTSG   +PS   T      +KTSTS    + +TH   VT
Sbjct: 1878 PPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFST------AKTSTSLPYHTSSTHHPEVT 1931



 Score = 30.4 bits (67), Expect = 9.3
 Identities = 20/57 (35%), Positives = 31/57 (54%), Gaps = 5/57 (8%)

Query: 200  ETPRGCPVTSVTPYGTS---PTNALYPSLSTSMVSASVASTSVASSSVASSSVAYST 253
            E PR  P T+VTP  TS   PT  L  + +   V+ +    + +++S A++S A ST
Sbjct: 1270 EPPR--PTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATASTASPATTSTAQST 1324


>gi|239755778 PREDICTED: mucin 19, oligomeric [Homo sapiens]
          Length = 598

 Score = 73.2 bits (178), Expect = 1e-12
 Identities = 52/212 (24%), Positives = 92/212 (43%), Gaps = 28/212 (13%)

Query: 821  GPPSDAFVVSCETQICNTH--CPVGFEYQ--EQSGQCC--GTCVQVACVTNTSKSPAHLF 874
            G  +DA  + C+ + C +   C  G +    + +  CC  G C    C+ N +      +
Sbjct: 396  GTCTDAKTIDCKPEECPSPPTCKTGEKLVKFQSNDTCCEIGYCEPRTCLFNNTD-----Y 450

Query: 875  YPGETWSDAGNHCVTHQCEKHQDGLVVVTTKKACPPLSCSLDEARM-SKDGCCRFCPPPP 933
              G ++ D  N CV++ C+      VV    + CP  +   +  R+     CC  C    
Sbjct: 451  EIGASFDDPSNPCVSYSCKDTGFAAVV----QDCPKQTWCAEANRIYDSKKCCYTC---- 502

Query: 934  PPYQNQSTCAVYHRSLIIQQQGCSSSEPVRLAYCRGNCGDSSSMYSLEGNTVEHRCQCCQ 993
                 ++ C     ++ +   GC     V++A C G C + ++ Y+ +   +EH C CC+
Sbjct: 503  -----KNNCRSSLVNVTVIYSGCKKR--VQMAKCTGEC-EKTAKYNYDILLLEHSCLCCR 554

Query: 994  ELRTSLRNVTLHCTDGSSRAFSYTEVEECGCM 1025
            E    LR++ L C DGS+  + Y  +  C C+
Sbjct: 555  EENYELRDIVLDCPDGSTIPYQYKHITTCSCL 586



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 44/174 (25%), Positives = 57/174 (32%), Gaps = 46/174 (26%)

Query: 686 PRCLGPHGEPVKVGHTVGMDCQECTCEAATWTLTCRPKLCPLPPACPLPGFVPVPAAPQA 745
           P C GP GE    G     +C   TC  A  T+ C+P+ CP PP                
Sbjct: 373 PVCHGPLGEEKSPGDIWTANCHRGTCTDAK-TIDCKPEECPSPPT--------------- 416

Query: 746 GQCCPQYSCACNTSRCPKPVGCPEGARAIPTYQEGACCPVQNCSWTVCSINGTLYQPGAV 805
                                C  G + +       CC +  C    C  N T Y+ GA 
Sbjct: 417 ---------------------CKTGEKLVKFQSNDTCCEIGYCEPRTCLFNNTDYEIGAS 455

Query: 806 VS--SSLCETCRCELPGGPPSDAFVVSCETQICNTHCPVGFEYQEQSGQCCGTC 857
               S+ C +  C+  G     A V  C  Q   T C       + S +CC TC
Sbjct: 456 FDDPSNPCVSYSCKDTG---FAAVVQDCPKQ---TWCAEANRIYD-SKKCCYTC 502



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 32/110 (29%), Positives = 42/110 (38%), Gaps = 24/110 (21%)

Query: 315 ISTSEPVTE--LGCPNAVPP-----------RKKGETWATPNCSEATCEGNNVISLRPRT 361
           ++T E  TE    C  ++PP           +  G+ W T NC   TC     I  +P  
Sbjct: 352 VATREVETENKTECLASLPPAPVCHGPLGEEKSPGDIW-TANCHRGTCTDAKTIDCKPEE 410

Query: 362 CPRVEKPTCANGYPAVKVADQDGCCHHYQCQCVCSGWGDPHYITFDGTYY 411
           CP    PTC  G   VK    D CC          G+ +P    F+ T Y
Sbjct: 411 CP--SPPTCKTGEKLVKFQSNDTCCE--------IGYCEPRTCLFNNTDY 450


>gi|239750280 PREDICTED: mucin 19, oligomeric [Homo sapiens]
          Length = 598

 Score = 73.2 bits (178), Expect = 1e-12
 Identities = 52/212 (24%), Positives = 92/212 (43%), Gaps = 28/212 (13%)

Query: 821  GPPSDAFVVSCETQICNTH--CPVGFEYQ--EQSGQCC--GTCVQVACVTNTSKSPAHLF 874
            G  +DA  + C+ + C +   C  G +    + +  CC  G C    C+ N +      +
Sbjct: 396  GTCTDAKTIDCKPEECPSPPTCKTGEKLVKFQSNDTCCEIGYCEPRTCLFNNTD-----Y 450

Query: 875  YPGETWSDAGNHCVTHQCEKHQDGLVVVTTKKACPPLSCSLDEARM-SKDGCCRFCPPPP 933
              G ++ D  N CV++ C+      VV    + CP  +   +  R+     CC  C    
Sbjct: 451  EIGASFDDPSNPCVSYSCKDTGFAAVV----QDCPKQTWCAEANRIYDSKKCCYTC---- 502

Query: 934  PPYQNQSTCAVYHRSLIIQQQGCSSSEPVRLAYCRGNCGDSSSMYSLEGNTVEHRCQCCQ 993
                 ++ C     ++ +   GC     V++A C G C + ++ Y+ +   +EH C CC+
Sbjct: 503  -----KNNCRSSLVNVTVIYSGCKKR--VQMAKCTGEC-EKTAKYNYDILLLEHSCLCCR 554

Query: 994  ELRTSLRNVTLHCTDGSSRAFSYTEVEECGCM 1025
            E    LR++ L C DGS+  + Y  +  C C+
Sbjct: 555  EENYELRDIVLDCPDGSTIPYQYKHITTCSCL 586



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 44/174 (25%), Positives = 57/174 (32%), Gaps = 46/174 (26%)

Query: 686 PRCLGPHGEPVKVGHTVGMDCQECTCEAATWTLTCRPKLCPLPPACPLPGFVPVPAAPQA 745
           P C GP GE    G     +C   TC  A  T+ C+P+ CP PP                
Sbjct: 373 PVCHGPLGEEKSPGDIWTANCHRGTCTDAK-TIDCKPEECPSPPT--------------- 416

Query: 746 GQCCPQYSCACNTSRCPKPVGCPEGARAIPTYQEGACCPVQNCSWTVCSINGTLYQPGAV 805
                                C  G + +       CC +  C    C  N T Y+ GA 
Sbjct: 417 ---------------------CKTGEKLVKFQSNDTCCEIGYCEPRTCLFNNTDYEIGAS 455

Query: 806 VS--SSLCETCRCELPGGPPSDAFVVSCETQICNTHCPVGFEYQEQSGQCCGTC 857
               S+ C +  C+  G     A V  C  Q   T C       + S +CC TC
Sbjct: 456 FDDPSNPCVSYSCKDTG---FAAVVQDCPKQ---TWCAEANRIYD-SKKCCYTC 502



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 32/110 (29%), Positives = 42/110 (38%), Gaps = 24/110 (21%)

Query: 315 ISTSEPVTE--LGCPNAVPP-----------RKKGETWATPNCSEATCEGNNVISLRPRT 361
           ++T E  TE    C  ++PP           +  G+ W T NC   TC     I  +P  
Sbjct: 352 VATREVETENKTECLASLPPAPVCHGPLGEEKSPGDIW-TANCHRGTCTDAKTIDCKPEE 410

Query: 362 CPRVEKPTCANGYPAVKVADQDGCCHHYQCQCVCSGWGDPHYITFDGTYY 411
           CP    PTC  G   VK    D CC          G+ +P    F+ T Y
Sbjct: 411 CP--SPPTCKTGEKLVKFQSNDTCCE--------IGYCEPRTCLFNNTDY 450


>gi|239744589 PREDICTED: mucin 19 [Homo sapiens]
          Length = 598

 Score = 73.2 bits (178), Expect = 1e-12
 Identities = 52/212 (24%), Positives = 92/212 (43%), Gaps = 28/212 (13%)

Query: 821  GPPSDAFVVSCETQICNTH--CPVGFEYQ--EQSGQCC--GTCVQVACVTNTSKSPAHLF 874
            G  +DA  + C+ + C +   C  G +    + +  CC  G C    C+ N +      +
Sbjct: 396  GTCTDAKTIDCKPEECPSPPTCKTGEKLVKFQSNDTCCEIGYCEPRTCLFNNTD-----Y 450

Query: 875  YPGETWSDAGNHCVTHQCEKHQDGLVVVTTKKACPPLSCSLDEARM-SKDGCCRFCPPPP 933
              G ++ D  N CV++ C+      VV    + CP  +   +  R+     CC  C    
Sbjct: 451  EIGASFDDPSNPCVSYSCKDTGFAAVV----QDCPKQTWCAEANRIYDSKKCCYTC---- 502

Query: 934  PPYQNQSTCAVYHRSLIIQQQGCSSSEPVRLAYCRGNCGDSSSMYSLEGNTVEHRCQCCQ 993
                 ++ C     ++ +   GC     V++A C G C + ++ Y+ +   +EH C CC+
Sbjct: 503  -----KNNCRSSLVNVTVIYSGCKKR--VQMAKCTGEC-EKTAKYNYDILLLEHSCLCCR 554

Query: 994  ELRTSLRNVTLHCTDGSSRAFSYTEVEECGCM 1025
            E    LR++ L C DGS+  + Y  +  C C+
Sbjct: 555  EENYELRDIVLDCPDGSTIPYQYKHITTCSCL 586



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 44/174 (25%), Positives = 57/174 (32%), Gaps = 46/174 (26%)

Query: 686 PRCLGPHGEPVKVGHTVGMDCQECTCEAATWTLTCRPKLCPLPPACPLPGFVPVPAAPQA 745
           P C GP GE    G     +C   TC  A  T+ C+P+ CP PP                
Sbjct: 373 PVCHGPLGEEKSPGDIWTANCHRGTCTDAK-TIDCKPEECPSPPT--------------- 416

Query: 746 GQCCPQYSCACNTSRCPKPVGCPEGARAIPTYQEGACCPVQNCSWTVCSINGTLYQPGAV 805
                                C  G + +       CC +  C    C  N T Y+ GA 
Sbjct: 417 ---------------------CKTGEKLVKFQSNDTCCEIGYCEPRTCLFNNTDYEIGAS 455

Query: 806 VS--SSLCETCRCELPGGPPSDAFVVSCETQICNTHCPVGFEYQEQSGQCCGTC 857
               S+ C +  C+  G     A V  C  Q   T C       + S +CC TC
Sbjct: 456 FDDPSNPCVSYSCKDTG---FAAVVQDCPKQ---TWCAEANRIYD-SKKCCYTC 502



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 32/110 (29%), Positives = 42/110 (38%), Gaps = 24/110 (21%)

Query: 315 ISTSEPVTE--LGCPNAVPP-----------RKKGETWATPNCSEATCEGNNVISLRPRT 361
           ++T E  TE    C  ++PP           +  G+ W T NC   TC     I  +P  
Sbjct: 352 VATREVETENKTECLASLPPAPVCHGPLGEEKSPGDIW-TANCHRGTCTDAKTIDCKPEE 410

Query: 362 CPRVEKPTCANGYPAVKVADQDGCCHHYQCQCVCSGWGDPHYITFDGTYY 411
           CP    PTC  G   VK    D CC          G+ +P    F+ T Y
Sbjct: 411 CP--SPPTCKTGEKLVKFQSNDTCCE--------IGYCEPRTCLFNNTDY 450


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.452 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 53,234,143
Number of Sequences: 37866
Number of extensions: 3039652
Number of successful extensions: 27006
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 147
Number of HSP's successfully gapped in prelim test: 277
Number of HSP's that attempted gapping in prelim test: 16228
Number of HSP's gapped (non-prelim): 7034
length of query: 1064
length of database: 18,247,518
effective HSP length: 113
effective length of query: 951
effective length of database: 13,968,660
effective search space: 13284195660
effective search space used: 13284195660
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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