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Search of human proteins with 239755011
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo
sapiens]
(1363 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 2707 0.0
gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 2593 0.0
gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 2375 0.0
gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 2375 0.0
gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 2170 0.0
gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 1848 0.0
gi|154354990 ankyrin repeat domain 26 [Homo sapiens] 555 e-157
gi|60115723 ankyrin repeat domain 20 family, member A2 [Homo sap... 379 e-104
gi|60460920 ankyrin repeat domain 20 family, member A3 [Homo sap... 378 e-104
gi|156104901 ankyrin repeat domain 20 family, member A1 [Homo sa... 378 e-104
gi|149363679 ankyrin repeat domain 20 family, member A4 [Homo sa... 378 e-104
gi|239757009 PREDICTED: ankyrin repeat domain 20 family, member ... 358 3e-98
gi|239751523 PREDICTED: ankyrin repeat domain 20 family, member ... 358 3e-98
gi|239756999 PREDICTED: ankyrin repeat domain 62 [Homo sapiens] 285 2e-76
gi|239751514 PREDICTED: ankyrin repeat domain 62 isoform 4 [Homo... 285 2e-76
gi|239746016 PREDICTED: ankyrin repeat domain 62 isoform 1 [Homo... 283 8e-76
gi|53828703 POTE ankyrin domain family, member A isoform 2 [Homo... 252 1e-66
gi|149363642 coiled-coil domain containing 144A [Homo sapiens] 251 3e-66
gi|239745058 PREDICTED: hypothetical protein XP_002343353 [Homo ... 249 2e-65
gi|52856430 protein expressed in prostate, ovary, testis, and pl... 247 5e-65
gi|209977003 ANKRD26-like family C, member 3 [Homo sapiens] 244 3e-64
gi|52856434 POTE ankyrin domain family, member G [Homo sapiens] 243 7e-64
gi|224282147 prostate-specific P704P [Homo sapiens] 243 9e-64
gi|113413200 PREDICTED: similar to protein expressed in prostate... 243 9e-64
gi|134133226 protein expressed in prostate, ovary, testis, and p... 242 2e-63
gi|153791352 prostate, ovary, testis expressed protein on chromo... 242 2e-63
gi|153792284 pote protein [Homo sapiens] 241 3e-63
gi|239741769 PREDICTED: similar to protein expressed in prostate... 241 3e-63
gi|88953571 PREDICTED: similar to protein expressed in prostate,... 241 3e-63
gi|239741279 PREDICTED: similar to FLJ00310 protein [Homo sapiens] 241 3e-63
>gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1363
Score = 2707 bits (7016), Expect = 0.0
Identities = 1363/1363 (100%), Positives = 1363/1363 (100%)
Query: 1 MSPWLRPSQAVCPAAAAPGQEPTLSPIPADGPWSGPDLSSEKRGGSHGQAGRDARLRFWN 60
MSPWLRPSQAVCPAAAAPGQEPTLSPIPADGPWSGPDLSSEKRGGSHGQAGRDARLRFWN
Sbjct: 1 MSPWLRPSQAVCPAAAAPGQEPTLSPIPADGPWSGPDLSSEKRGGSHGQAGRDARLRFWN 60
Query: 61 VPRQPRRTRKPAAPEPELQSPSAGHASSRAPSGVRAVATMRKLLSFGRRLGQALLSSMDQ 120
VPRQPRRTRKPAAPEPELQSPSAGHASSRAPSGVRAVATMRKLLSFGRRLGQALLSSMDQ
Sbjct: 61 VPRQPRRTRKPAAPEPELQSPSAGHASSRAPSGVRAVATMRKLLSFGRRLGQALLSSMDQ 120
Query: 121 EYAGRGYHIRDWELRKIHRAAIKGDAAEVEHCLTRRFRDLDVRDKKDRTVLHLACAHGRV 180
EYAGRGYHIRDWELRKIHRAAIKGDAAEVEHCLTRRFRDLDVRDKKDRTVLHLACAHGRV
Sbjct: 121 EYAGRGYHIRDWELRKIHRAAIKGDAAEVEHCLTRRFRDLDVRDKKDRTVLHLACAHGRV 180
Query: 181 QVVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAIILLKRGANPNIKDIYGNTALHYA 240
QVVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAIILLKRGANPNIKDIYGNTALHYA
Sbjct: 181 QVVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAIILLKRGANPNIKDIYGNTALHYA 240
Query: 241 VYNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNFKR 300
VYNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNFKR
Sbjct: 241 VYNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNFKR 300
Query: 301 TALILAVQHNLSSIVTLLLQQNIHISSQDMFGQTAEDYAFCCDLRSIQQQILEHKNKMLK 360
TALILAVQHNLSSIVTLLLQQNIHISSQDMFGQTAEDYAFCCDLRSIQQQILEHKNKMLK
Sbjct: 301 TALILAVQHNLSSIVTLLLQQNIHISSQDMFGQTAEDYAFCCDLRSIQQQILEHKNKMLK 360
Query: 361 NHLRNDNQETAAMKPENLKKRKKRKKLKKRKEGAKAEHNLKVASEEKQERLERSENKQPQ 420
NHLRNDNQETAAMKPENLKKRKKRKKLKKRKEGAKAEHNLKVASEEKQERLERSENKQPQ
Sbjct: 361 NHLRNDNQETAAMKPENLKKRKKRKKLKKRKEGAKAEHNLKVASEEKQERLERSENKQPQ 420
Query: 421 DSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKS 480
DSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKS
Sbjct: 421 DSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKS 480
Query: 481 VRLNEEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHNKERLEAEVESLHSNLATAINE 540
VRLNEEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHNKERLEAEVESLHSNLATAINE
Sbjct: 481 VRLNEEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHNKERLEAEVESLHSNLATAINE 540
Query: 541 YNEILERKDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRE 600
YNEILERKDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRE
Sbjct: 541 YNEILERKDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRE 600
Query: 601 TRDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAKESQSIGKQNSSEERIRQRELE 660
TRDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAKESQSIGKQNSSEERIRQRELE
Sbjct: 601 TRDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAKESQSIGKQNSSEERIRQRELE 660
Query: 661 NLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKELMNEYNYLKEKLLQYEK 720
NLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKELMNEYNYLKEKLLQYEK
Sbjct: 661 NLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKELMNEYNYLKEKLLQYEK 720
Query: 721 EKAEREVIVREFQEELVDHLKKFSMSESPLEGTSHCHINLDETWTSKKKLFQVEIQPEEK 780
EKAEREVIVREFQEELVDHLKKFSMSESPLEGTSHCHINLDETWTSKKKLFQVEIQPEEK
Sbjct: 721 EKAEREVIVREFQEELVDHLKKFSMSESPLEGTSHCHINLDETWTSKKKLFQVEIQPEEK 780
Query: 781 HEEFRKVFELISLLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDL 840
HEEFRKVFELISLLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDL
Sbjct: 781 HEEFRKVFELISLLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDL 840
Query: 841 NTDQLKMDILFKKLKQKFDDLMAEKEAVSSKCVNLAKDNEVLHQELLSMGKVQEKCEKLE 900
NTDQLKMDILFKKLKQKFDDLMAEKEAVSSKCVNLAKDNEVLHQELLSMGKVQEKCEKLE
Sbjct: 841 NTDQLKMDILFKKLKQKFDDLMAEKEAVSSKCVNLAKDNEVLHQELLSMGKVQEKCEKLE 900
Query: 901 KDKKMLEEKVLNLKTHMEKDMVELGKVQEYKSELDERAMQAIEKLEEIHLQKQAEYEKQL 960
KDKKMLEEKVLNLKTHMEKDMVELGKVQEYKSELDERAMQAIEKLEEIHLQKQAEYEKQL
Sbjct: 901 KDKKMLEEKVLNLKTHMEKDMVELGKVQEYKSELDERAMQAIEKLEEIHLQKQAEYEKQL 960
Query: 961 EQLNKDNTASLKKKELTLKDVECKFSKMKTAYEDVTTELEEYKEAFAVALKANSSMSEKI 1020
EQLNKDNTASLKKKELTLKDVECKFSKMKTAYEDVTTELEEYKEAFAVALKANSSMSEKI
Sbjct: 961 EQLNKDNTASLKKKELTLKDVECKFSKMKTAYEDVTTELEEYKEAFAVALKANSSMSEKI 1020
Query: 1021 TKSDKKIAVISTKLFMEKERMEYFLSTLPMRPDPELPCVENLNSIELNRKYIPKMAIRIP 1080
TKSDKKIAVISTKLFMEKERMEYFLSTLPMRPDPELPCVENLNSIELNRKYIPKMAIRIP
Sbjct: 1021 TKSDKKIAVISTKLFMEKERMEYFLSTLPMRPDPELPCVENLNSIELNRKYIPKMAIRIP 1080
Query: 1081 TSNPQTSNNCKNSLTELLLRWALAPIYFLLXNPLHCLGDLQLYTRPGFHLERVPALSALL 1140
TSNPQTSNNCKNSLTELLLRWALAPIYFLL NPLHCLGDLQLYTRPGFHLERVPALSALL
Sbjct: 1081 TSNPQTSNNCKNSLTELLLRWALAPIYFLLXNPLHCLGDLQLYTRPGFHLERVPALSALL 1140
Query: 1141 GAPPLSASLGPPLVERAEIGEHLWEALILALGPGGDSDEDLGSCCGGLCHPTMSLLLSPH 1200
GAPPLSASLGPPLVERAEIGEHLWEALILALGPGGDSDEDLGSCCGGLCHPTMSLLLSPH
Sbjct: 1141 GAPPLSASLGPPLVERAEIGEHLWEALILALGPGGDSDEDLGSCCGGLCHPTMSLLLSPH 1200
Query: 1201 RLCVLEQLETHSSLCEWLCVKDCFLGEMHISTQLTAQTQQFHSASPLDTPRTXQDNPIMA 1260
RLCVLEQLETHSSLCEWLCVKDCFLGEMHISTQLTAQTQQFHSASPLDTPRT QDNPIMA
Sbjct: 1201 RLCVLEQLETHSSLCEWLCVKDCFLGEMHISTQLTAQTQQFHSASPLDTPRTXQDNPIMA 1260
Query: 1261 LSPGPVWLHDNQHAGPETTALLDAFNTVGELXANQPIQELDPVMDLLVLSQGHQVNIPDI 1320
LSPGPVWLHDNQHAGPETTALLDAFNTVGEL ANQPIQELDPVMDLLVLSQGHQVNIPDI
Sbjct: 1261 LSPGPVWLHDNQHAGPETTALLDAFNTVGELXANQPIQELDPVMDLLVLSQGHQVNIPDI 1320
Query: 1321 IHIHKEALTKVMESRQHVAEGKTEVQRLMMSESQEQDFFGHCG 1363
IHIHKEALTKVMESRQHVAEGKTEVQRLMMSESQEQDFFGHCG
Sbjct: 1321 IHIHKEALTKVMESRQHVAEGKTEVQRLMMSESQEQDFFGHCG 1363
>gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1366
Score = 2593 bits (6721), Expect = 0.0
Identities = 1326/1392 (95%), Positives = 1326/1392 (95%), Gaps = 55/1392 (3%)
Query: 1 MSPWLRPSQAVCPAAAAPGQEPTLSPIPADGPWSGPDLSSEKRGGSHGQAGRDARLRFWN 60
MSPWLRPSQAVCPAAAAPGQEPTLSPIPADGPWSGPDLSSEKRGGSHGQAGRDARLRF N
Sbjct: 1 MSPWLRPSQAVCPAAAAPGQEPTLSPIPADGPWSGPDLSSEKRGGSHGQAGRDARLRFRN 60
Query: 61 VPRQPRRTRKPAAPEPELQSPSAGHASSRAPSGVRA------------------------ 96
VPRQPRRTRKPAAPEPELQSPSAGHASSRAPSGVRA
Sbjct: 61 VPRQPRRTRKPAAPEPELQSPSAGHASSRAPSGVRAGAELGRRLRVSLLKAVVDRAGSRI 120
Query: 97 -----VATMRKLLSFGRRLGQALLSSMDQEYAGRGYHIRDWELRKIHRAAIKGDAAEVEH 151
VATMRKLLSFGRRLGQALLSSMDQEYAGRGYHIRDWELRKIHRAAIKGDAAEVEH
Sbjct: 121 LSYIAVATMRKLLSFGRRLGQALLSSMDQEYAGRGYHIRDWELRKIHRAAIKGDAAEVEH 180
Query: 152 CLTRRFRDLDVRDKKDRTVLHLACAHGRVQVVTLLLDRKCQINICDRLNRTPLMKAVHCQ 211
CLTRRFRDLDVRDKKDRTVLHLACAHGRVQVVTLLLDRKCQINICDRLNRTPLMKAVHCQ
Sbjct: 181 CLTRRFRDLDVRDKKDRTVLHLACAHGRVQVVTLLLDRKCQINICDRLNRTPLMKAVHCQ 240
Query: 212 EEACAIILLKRGANPNIKDIYGNTALHYAVYNEGTSLAERLLSHHANIEALNKEGNTPLL 271
EEACAIILLKRGANPNIKDIYGNTALHYAVYNEGTSLAERLLSHHANIEALNKEGNTPLL
Sbjct: 241 EEACAIILLKRGANPNIKDIYGNTALHYAVYNEGTSLAERLLSHHANIEALNKEGNTPLL 300
Query: 272 FAINSRRQHMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIHISSQDMF 331
FAINSRRQHMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIHISSQDMF
Sbjct: 301 FAINSRRQHMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIHISSQDMF 360
Query: 332 GQTAEDYAFCCDLRSIQQQILEHKNKMLKNHLRNDNQETAAMKPENLKKRKKRKKLKKRK 391
GQTAEDYAFCCDLRSIQQQILEHKNKMLKNHLRNDNQETAAMKPENLKKRKKRKKLKKRK
Sbjct: 361 GQTAEDYAFCCDLRSIQQQILEHKNKMLKNHLRNDNQETAAMKPENLKKRKKRKKLKKRK 420
Query: 392 EGAKAEHNLKVASEEKQERLERSENKQPQDSQSYGKKKDEMFGNFMLKRDIAMLKEELYA 451
EGAKAEHNLKVASEEKQERLERSENKQPQDSQSYGKKKDEMFGNFMLKRDIAMLKEELYA
Sbjct: 421 EGAKAEHNLKVASEEKQERLERSENKQPQDSQSYGKKKDEMFGNFMLKRDIAMLKEELYA 480
Query: 452 IKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEEMITKKVAQYSQQLNDLKAENARLNS 511
IKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEEMITKKVAQYSQQLNDLKAENARLNS
Sbjct: 481 IKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEEMITKKVAQYSQQLNDLKAENARLNS 540
Query: 512 KLEKEKHNKERLEAEVESLHSNLATAINEYNEILERKDLELVLWRADDVSRHETMGSNIS 571
KLEKEKHNKERLEAEVESLHSNLATAINEYNEILERKDLELVLWRADDVSRHETMGSNIS
Sbjct: 541 KLEKEKHNKERLEAEVESLHSNLATAINEYNEILERKDLELVLWRADDVSRHETMGSNIS 600
Query: 572 QLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKTLALESVQLDLKQAQHRIKEMKQ 631
QLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKTLALESVQLDLKQAQHRIKEMKQ
Sbjct: 601 QLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKTLALESVQLDLKQAQHRIKEMKQ 660
Query: 632 MHPNGEAKESQSIGKQNSSEERIRQRELENLLLERQLEDARKEGDNKEIVINIHRDCLEN 691
MHPNGEAKESQSIGKQNSSEERIRQRELENLLLERQLEDARKEGDNKEIVINIHRDCLEN
Sbjct: 661 MHPNGEAKESQSIGKQNSSEERIRQRELENLLLERQLEDARKEGDNKEIVINIHRDCLEN 720
Query: 692 GKEDLLEERNKELMNEYNYLKEKLLQYEKEKAEREVIVREFQEELVDHLKKFSMSESPLE 751
GKEDLLEERNKELMNEYNYLKEKLLQYEKEKAEREVIVREFQEELVDHLKKFSMSESPLE
Sbjct: 721 GKEDLLEERNKELMNEYNYLKEKLLQYEKEKAEREVIVREFQEELVDHLKKFSMSESPLE 780
Query: 752 GTSHCHINLDETWTSKKKLFQVEIQPEEKHEEFRKVFELISLLNYTADQIRKKNRELEEE 811
GTSHCHINLDETWTSKKKLFQVEIQPEEKHEEFRKVFELISLLNYTADQIRKKNRELEEE
Sbjct: 781 GTSHCHINLDETWTSKKKLFQVEIQPEEKHEEFRKVFELISLLNYTADQIRKKNRELEEE 840
Query: 812 ATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFDDLMAEKEAVSSK 871
ATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFDDLMAEKEAVSSK
Sbjct: 841 ATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFDDLMAEKEAVSSK 900
Query: 872 CVNLAKDNEVLHQELLSMGKVQEKCEKLEKDKKMLEEKVLNLKTHMEKDMVELGKVQEYK 931
CVNLAKDNEVLHQELLSMGKVQEKCEKLEKDKKMLEEKVLNLKTHMEKDMVELGKVQEYK
Sbjct: 901 CVNLAKDNEVLHQELLSMGKVQEKCEKLEKDKKMLEEKVLNLKTHMEKDMVELGKVQEYK 960
Query: 932 SELDERAMQAIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSKMKTA 991
SELDERAMQAIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSKMKTA
Sbjct: 961 SELDERAMQAIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSKMKTA 1020
Query: 992 YEDVTTELEEYKEAFAVALKANSSMSEKITKSDKKIAVISTKLFMEKERMEYFLSTLPMR 1051
YEDVTTELEEYKEAFAVALKANSSMSEKITKSDKKIAVISTKLFMEKERMEYFLSTLPMR
Sbjct: 1021 YEDVTTELEEYKEAFAVALKANSSMSEKITKSDKKIAVISTKLFMEKERMEYFLSTLPMR 1080
Query: 1052 PDPELPCVENLNSIELNRKYIPKMAIRIPTSNPQTSNNCKNSLTELLLRWALAPIYFLLX 1111
PDPELPCVENLNSIELNRKYIPKMAIRIPTSNPQTSNNCKNSLTELLLRWALAPIYFLL
Sbjct: 1081 PDPELPCVENLNSIELNRKYIPKMAIRIPTSNPQTSNNCKNSLTELLLRWALAPIYFLLX 1140
Query: 1112 NPLHCLGDLQLYTRPGFHLERVPALSALLGAPPLSASLGPPLVERAEIGEHLWEALILAL 1171
NPL P A GPP VER EIGEHLWEALILAL
Sbjct: 1141 NPLM--------------------------GPEGLAGEGPPSVEREEIGEHLWEALILAL 1174
Query: 1172 GPGGDSDEDLGSCCGGLCHPTMSLLLSPHRLCVLEQLETHSSLCEWLCVKDCFLGEMHIS 1231
GPGGDSDEDLGSCCGGLCHPTMSLLLSPHRLCVLEQLETHSSLCEWLCVKDCFLGEMHIS
Sbjct: 1175 GPGGDSDEDLGSCCGGLCHPTMSLLLSPHRLCVLEQLETHSSLCEWLCVKDCFLGEMHIS 1234
Query: 1232 TQLTAQTQQFHSASPLDTPRTXQDNPIMALSPGPVWLHDNQHAGPETTALLDAFNTVGEL 1291
TQLTAQTQQFHSASPLDTPRT QDNPIMALSPGPVWLHDNQ AGPETTALLDAFNTVGEL
Sbjct: 1235 TQLTAQTQQFHSASPLDTPRTXQDNPIMALSPGPVWLHDNQDAGPETTALLDAFNTVGEL 1294
Query: 1292 XANQPIQELDPVMDLLVLSQGHQVNIPDIIHIHKEALTKVMESRQHVAEGKTEVQRLMMS 1351
ANQPIQELDPVMDLLVLSQGHQVNIPDIIHIHKEALTKVMESRQHVAEGKTEVQRLMMS
Sbjct: 1295 XANQPIQELDPVMDLLVLSQGHQVNIPDIIHIHKEALTKVMESRQHVAEGKTEVQRLMMS 1354
Query: 1352 ESQEQDFFGHCG 1363
ESQEQDFFGHCG
Sbjct: 1355 ESQEQDFFGHCG 1366
>gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1415
Score = 2375 bits (6154), Expect = 0.0
Identities = 1233/1424 (86%), Positives = 1279/1424 (89%), Gaps = 70/1424 (4%)
Query: 1 MSPWLRPSQAVCPAAAAPGQEPTLSPIPA---DGPWSGPDLSSEK-RGGSHGQAG----R 52
MSPWLRPSQAV PAAAAPGQEPT P P SGPDLSSE+ R GS GQAG R
Sbjct: 1 MSPWLRPSQAVYPAAAAPGQEPTPQSHPRWLRRAPVSGPDLSSEEERVGSQGQAGPQAGR 60
Query: 53 DARLRFWNVPRQPRRTRKPAAPEPELQSPSAGHASSRAPSGVRAVATMRKLLSFGRRLGQ 112
DA L F +VPR+PRRTRKPA P LQ P AGH A SGV AVATMRKL SFGRRLGQ
Sbjct: 61 DALLGFRDVPREPRRTRKPATRAPVLQVPPAGHEGLGAASGVPAVATMRKLFSFGRRLGQ 120
Query: 113 ALLSSMDQEYAGRGYHIRDWELRKIHRAAIKGDAAEVEHCLTRRFRDLDVRDKKDRTVLH 172
ALLSSMDQEYAG GY IRDWELRKIHRAAIKGDAAEVE CLTRRFRDLD RD+KDRTVLH
Sbjct: 121 ALLSSMDQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLDARDRKDRTVLH 180
Query: 173 LACAHGRVQVVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAIILLKRGANPNIKDIY 232
LACAHGRVQVVTLLL R+CQI+ICDRLNRTPLMKAVH QEEACAI+LL+ GANPNI+DIY
Sbjct: 181 LACAHGRVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLECGANPNIEDIY 240
Query: 233 GNTALHYAVYNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANI 292
GNTALHYAVYN+GTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANI
Sbjct: 241 GNTALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANI 300
Query: 293 HAVDNFKRTALILAVQHNLSSIVTLLLQQNIHISSQDMFGQTAEDYAFCCDLRSIQQQIL 352
HAVDNFKRTALILAVQHNLSSIVTLLLQQNI ISSQDMFGQTAEDYA C DLRSI+QQIL
Sbjct: 301 HAVDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQIL 360
Query: 353 EHKNKMLKNHLRNDNQETAAMKPENLKKRKKRKKLKKRKEGAKAEHNLKVASEEKQERLE 412
EHKNKMLKNHLRNDNQETAAMKP NLKKRK+R AKAEHNLKVASEEKQERL+
Sbjct: 361 EHKNKMLKNHLRNDNQETAAMKPANLKKRKER---------AKAEHNLKVASEEKQERLQ 411
Query: 413 RSENKQPQDSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSLRKEKKYIQEIKSITE 472
RSENKQPQDSQSYGKKKD M+GNFMLK+DIAMLKEELYAIKNDSLRKEKKYIQEIKSITE
Sbjct: 412 RSENKQPQDSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYIQEIKSITE 471
Query: 473 INANFEKSVRLNEEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHNKERLEAEVESLHS 532
INANFEKSVRLNE+MITK VA+YSQQLNDLKAENARLNS+LEKEKHNKERLEAEVESLHS
Sbjct: 472 INANFEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVESLHS 531
Query: 533 NLATAINEYNEILERKDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKARVKFN 592
+LATAINEYNEI+ERKDLELVLWRADDVSRHE MGSNISQLTDKNELLTEQVHKARVKFN
Sbjct: 532 SLATAINEYNEIVERKDLELVLWRADDVSRHEKMGSNISQLTDKNELLTEQVHKARVKFN 591
Query: 593 TLKGKLRETRDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAKESQSIGKQNSSEE 652
TLKGKLRETRDALREKTLAL SVQLDL+QAQHRIKEMKQMHPNGEAKESQSIGKQNS EE
Sbjct: 592 TLKGKLRETRDALREKTLALGSVQLDLRQAQHRIKEMKQMHPNGEAKESQSIGKQNSLEE 651
Query: 653 RIRQRELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKELMNEYNYLK 712
RIRQ+ELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKELM EYNYLK
Sbjct: 652 RIRQQELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKELMKEYNYLK 711
Query: 713 EKLLQYEKEKAEREVIVREFQEELVDHLKKFSMSESPLEGTSHCHINLDETWTSKKKLFQ 772
EKLLQ EKEKAEREVIVREFQEELVDHLK FS+SESPLEGTSHCHINL+ETWTSKKKLFQ
Sbjct: 712 EKLLQCEKEKAEREVIVREFQEELVDHLKTFSISESPLEGTSHCHINLNETWTSKKKLFQ 771
Query: 773 VEIQPEEKHEEFRKVFELISLLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNAFANE 832
VEIQPEEKHEEFRK+FELISLLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNAFANE
Sbjct: 772 VEIQPEEKHEEFRKLFELISLLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNAFANE 831
Query: 833 DFSCHGDLNTDQLKMDILFKKLKQKFDDLMAEKEAVSSKCVNLAKDNEVLHQELLSMGKV 892
DFSCHGDLNTDQLKMDILFKKLKQKF+DL+AEKEAVSS+CVNLAKDNEVLHQELLSM V
Sbjct: 832 DFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSECVNLAKDNEVLHQELLSMRNV 891
Query: 893 QEKCEKLEKDKKMLEEKVLNLKTHMEKDMVELGKVQEYKSELDERAMQAIEKLEEIHLQK 952
QEKCEKLEKDKKMLEE+VLNLKTHMEKDMVELGK+QEYKSELDERA+Q IEKLEEIHLQK
Sbjct: 892 QEKCEKLEKDKKMLEEEVLNLKTHMEKDMVELGKLQEYKSELDERAVQEIEKLEEIHLQK 951
Query: 953 QAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSKMKTAYEDVTTELEEYKEAFAVALKA 1012
QAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSKMKTAYE+VTTELEE+KEAFA A+KA
Sbjct: 952 QAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSKMKTAYEEVTTELEEFKEAFAGAVKA 1011
Query: 1013 NSSMSEKITKSDKKIAVISTKLFMEKERMEYFLSTLPMRPDPELPCVENLNSIELNRKYI 1072
N+SMS+K+ KSDKKIAVISTKLF EK+RM+YFLSTLP RP+PELPCVENLNSIELNRKYI
Sbjct: 1012 NNSMSKKLMKSDKKIAVISTKLFTEKQRMKYFLSTLPTRPEPELPCVENLNSIELNRKYI 1071
Query: 1073 PKMAIRIPTSNPQTSNNCKNSLTELLLRWALAPIYFLLXNPLHCLGDLQLYTRPGFHLER 1132
PK AIRIPTSNPQTSNNCKN LTE+LL ALAP+YFLL NPLHCL DLQLYT PGFHLER
Sbjct: 1072 PKTAIRIPTSNPQTSNNCKNFLTEVLLCXALAPVYFLLXNPLHCLADLQLYTVPGFHLER 1131
Query: 1133 VPALSALLGAPPLSASLGPPLVERAEIGEHLWEALILALGPGGDSDEDL----------- 1181
VPALSALLG PPLSAS GPP VER EIGEHLWEALILALGPGGDSDEDL
Sbjct: 1132 VPALSALLGTPPLSASPGPPSVEREEIGEHLWEALILALGPGGDSDEDLGAPVSGAARPG 1191
Query: 1182 ------------------------------------------GSCCGGLCHPTMSLLLSP 1199
GSCCGGLCHPTMSLLLSP
Sbjct: 1192 QRSKTNKHTHMYTHTRIHKHNACTHVSSGDRGHRLWALLTQAGSCCGGLCHPTMSLLLSP 1251
Query: 1200 HRLCVLEQLETHSSLCEWLCVKDCFLGEMHISTQLTAQTQQFHSASPLDTPRTXQDNPIM 1259
HRLCV+EQLET SSLCEWLC+KDCFLGE HISTQLT +TQQFHSASPLDTPRT QDNPIM
Sbjct: 1252 HRLCVVEQLETRSSLCEWLCMKDCFLGERHISTQLTDRTQQFHSASPLDTPRTXQDNPIM 1311
Query: 1260 ALSPGPVWLHDNQHAGPETTALLDAFNTVGELXANQPIQELDPVMDLLVLSQGHQVNIPD 1319
ALSPGPV L DNQ AGPETTALLDAFNTVGEL ANQP QELDPVMDLLVLS GHQV I D
Sbjct: 1312 ALSPGPVSLRDNQDAGPETTALLDAFNTVGELFANQPSQELDPVMDLLVLSLGHQVIILD 1371
Query: 1320 IIHIHKEALTKVMESRQHVAEGKTEVQRLMMSESQEQDFFGHCG 1363
IIHIHKEALTKVMESRQHVAEGKTE+QRLM SESQEQDFFGHCG
Sbjct: 1372 IIHIHKEALTKVMESRQHVAEGKTEMQRLMTSESQEQDFFGHCG 1415
>gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1415
Score = 2375 bits (6154), Expect = 0.0
Identities = 1233/1424 (86%), Positives = 1279/1424 (89%), Gaps = 70/1424 (4%)
Query: 1 MSPWLRPSQAVCPAAAAPGQEPTLSPIPA---DGPWSGPDLSSEK-RGGSHGQAG----R 52
MSPWLRPSQAV PAAAAPGQEPT P P SGPDLSSE+ R GS GQAG R
Sbjct: 1 MSPWLRPSQAVYPAAAAPGQEPTPQSHPRWLRRAPVSGPDLSSEEERVGSQGQAGPQAGR 60
Query: 53 DARLRFWNVPRQPRRTRKPAAPEPELQSPSAGHASSRAPSGVRAVATMRKLLSFGRRLGQ 112
DA L F +VPR+PRRTRKPA P LQ P AGH A SGV AVATMRKL SFGRRLGQ
Sbjct: 61 DALLGFRDVPREPRRTRKPATRAPVLQVPPAGHEGLGAASGVPAVATMRKLFSFGRRLGQ 120
Query: 113 ALLSSMDQEYAGRGYHIRDWELRKIHRAAIKGDAAEVEHCLTRRFRDLDVRDKKDRTVLH 172
ALLSSMDQEYAG GY IRDWELRKIHRAAIKGDAAEVE CLTRRFRDLD RD+KDRTVLH
Sbjct: 121 ALLSSMDQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLDARDRKDRTVLH 180
Query: 173 LACAHGRVQVVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAIILLKRGANPNIKDIY 232
LACAHGRVQVVTLLL R+CQI+ICDRLNRTPLMKAVH QEEACAI+LL+ GANPNI+DIY
Sbjct: 181 LACAHGRVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLECGANPNIEDIY 240
Query: 233 GNTALHYAVYNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANI 292
GNTALHYAVYN+GTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANI
Sbjct: 241 GNTALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANI 300
Query: 293 HAVDNFKRTALILAVQHNLSSIVTLLLQQNIHISSQDMFGQTAEDYAFCCDLRSIQQQIL 352
HAVDNFKRTALILAVQHNLSSIVTLLLQQNI ISSQDMFGQTAEDYA C DLRSI+QQIL
Sbjct: 301 HAVDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQIL 360
Query: 353 EHKNKMLKNHLRNDNQETAAMKPENLKKRKKRKKLKKRKEGAKAEHNLKVASEEKQERLE 412
EHKNKMLKNHLRNDNQETAAMKP NLKKRK+R AKAEHNLKVASEEKQERL+
Sbjct: 361 EHKNKMLKNHLRNDNQETAAMKPANLKKRKER---------AKAEHNLKVASEEKQERLQ 411
Query: 413 RSENKQPQDSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSLRKEKKYIQEIKSITE 472
RSENKQPQDSQSYGKKKD M+GNFMLK+DIAMLKEELYAIKNDSLRKEKKYIQEIKSITE
Sbjct: 412 RSENKQPQDSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYIQEIKSITE 471
Query: 473 INANFEKSVRLNEEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHNKERLEAEVESLHS 532
INANFEKSVRLNE+MITK VA+YSQQLNDLKAENARLNS+LEKEKHNKERLEAEVESLHS
Sbjct: 472 INANFEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVESLHS 531
Query: 533 NLATAINEYNEILERKDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKARVKFN 592
+LATAINEYNEI+ERKDLELVLWRADDVSRHE MGSNISQLTDKNELLTEQVHKARVKFN
Sbjct: 532 SLATAINEYNEIVERKDLELVLWRADDVSRHEKMGSNISQLTDKNELLTEQVHKARVKFN 591
Query: 593 TLKGKLRETRDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAKESQSIGKQNSSEE 652
TLKGKLRETRDALREKTLAL SVQLDL+QAQHRIKEMKQMHPNGEAKESQSIGKQNS EE
Sbjct: 592 TLKGKLRETRDALREKTLALGSVQLDLRQAQHRIKEMKQMHPNGEAKESQSIGKQNSLEE 651
Query: 653 RIRQRELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKELMNEYNYLK 712
RIRQ+ELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKELM EYNYLK
Sbjct: 652 RIRQQELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKELMKEYNYLK 711
Query: 713 EKLLQYEKEKAEREVIVREFQEELVDHLKKFSMSESPLEGTSHCHINLDETWTSKKKLFQ 772
EKLLQ EKEKAEREVIVREFQEELVDHLK FS+SESPLEGTSHCHINL+ETWTSKKKLFQ
Sbjct: 712 EKLLQCEKEKAEREVIVREFQEELVDHLKTFSISESPLEGTSHCHINLNETWTSKKKLFQ 771
Query: 773 VEIQPEEKHEEFRKVFELISLLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNAFANE 832
VEIQPEEKHEEFRK+FELISLLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNAFANE
Sbjct: 772 VEIQPEEKHEEFRKLFELISLLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNAFANE 831
Query: 833 DFSCHGDLNTDQLKMDILFKKLKQKFDDLMAEKEAVSSKCVNLAKDNEVLHQELLSMGKV 892
DFSCHGDLNTDQLKMDILFKKLKQKF+DL+AEKEAVSS+CVNLAKDNEVLHQELLSM V
Sbjct: 832 DFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSECVNLAKDNEVLHQELLSMRNV 891
Query: 893 QEKCEKLEKDKKMLEEKVLNLKTHMEKDMVELGKVQEYKSELDERAMQAIEKLEEIHLQK 952
QEKCEKLEKDKKMLEE+VLNLKTHMEKDMVELGK+QEYKSELDERA+Q IEKLEEIHLQK
Sbjct: 892 QEKCEKLEKDKKMLEEEVLNLKTHMEKDMVELGKLQEYKSELDERAVQEIEKLEEIHLQK 951
Query: 953 QAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSKMKTAYEDVTTELEEYKEAFAVALKA 1012
QAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSKMKTAYE+VTTELEE+KEAFA A+KA
Sbjct: 952 QAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSKMKTAYEEVTTELEEFKEAFAGAVKA 1011
Query: 1013 NSSMSEKITKSDKKIAVISTKLFMEKERMEYFLSTLPMRPDPELPCVENLNSIELNRKYI 1072
N+SMS+K+ KSDKKIAVISTKLF EK+RM+YFLSTLP RP+PELPCVENLNSIELNRKYI
Sbjct: 1012 NNSMSKKLMKSDKKIAVISTKLFTEKQRMKYFLSTLPTRPEPELPCVENLNSIELNRKYI 1071
Query: 1073 PKMAIRIPTSNPQTSNNCKNSLTELLLRWALAPIYFLLXNPLHCLGDLQLYTRPGFHLER 1132
PK AIRIPTSNPQTSNNCKN LTE+LL ALAP+YFLL NPLHCL DLQLYT PGFHLER
Sbjct: 1072 PKTAIRIPTSNPQTSNNCKNFLTEVLLCXALAPVYFLLXNPLHCLADLQLYTVPGFHLER 1131
Query: 1133 VPALSALLGAPPLSASLGPPLVERAEIGEHLWEALILALGPGGDSDEDL----------- 1181
VPALSALLG PPLSAS GPP VER EIGEHLWEALILALGPGGDSDEDL
Sbjct: 1132 VPALSALLGTPPLSASPGPPSVEREEIGEHLWEALILALGPGGDSDEDLGAPVSGAARPG 1191
Query: 1182 ------------------------------------------GSCCGGLCHPTMSLLLSP 1199
GSCCGGLCHPTMSLLLSP
Sbjct: 1192 QRSKTNKHTHMYTHTRIHKHNACTHVSSGDRGHRLWALLTQAGSCCGGLCHPTMSLLLSP 1251
Query: 1200 HRLCVLEQLETHSSLCEWLCVKDCFLGEMHISTQLTAQTQQFHSASPLDTPRTXQDNPIM 1259
HRLCV+EQLET SSLCEWLC+KDCFLGE HISTQLT +TQQFHSASPLDTPRT QDNPIM
Sbjct: 1252 HRLCVVEQLETRSSLCEWLCMKDCFLGERHISTQLTDRTQQFHSASPLDTPRTXQDNPIM 1311
Query: 1260 ALSPGPVWLHDNQHAGPETTALLDAFNTVGELXANQPIQELDPVMDLLVLSQGHQVNIPD 1319
ALSPGPV L DNQ AGPETTALLDAFNTVGEL ANQP QELDPVMDLLVLS GHQV I D
Sbjct: 1312 ALSPGPVSLRDNQDAGPETTALLDAFNTVGELFANQPSQELDPVMDLLVLSLGHQVIILD 1371
Query: 1320 IIHIHKEALTKVMESRQHVAEGKTEVQRLMMSESQEQDFFGHCG 1363
IIHIHKEALTKVMESRQHVAEGKTE+QRLM SESQEQDFFGHCG
Sbjct: 1372 IIHIHKEALTKVMESRQHVAEGKTEMQRLMTSESQEQDFFGHCG 1415
>gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1139
Score = 2170 bits (5622), Expect = 0.0
Identities = 1108/1139 (97%), Positives = 1109/1139 (97%), Gaps = 29/1139 (2%)
Query: 1 MSPWLRPSQAVCPAAAAPGQEPTLSPIPADGPWSGPDLSSEKRGGSHGQAGRDARLRFWN 60
MSPWLRPSQAVCPAAAAPGQEPTLSPIPADGPWSGPDLSSEKRGGSHGQAGRDARLRF N
Sbjct: 1 MSPWLRPSQAVCPAAAAPGQEPTLSPIPADGPWSGPDLSSEKRGGSHGQAGRDARLRFRN 60
Query: 61 VPRQPRRTRKPAAPEPELQSPSAGHASSRAPSGVRA------------------------ 96
VPRQPRRTRKPAAPEPELQSPSAGHASSRAPSGVRA
Sbjct: 61 VPRQPRRTRKPAAPEPELQSPSAGHASSRAPSGVRAGAELGRRLRVSLLKAVVDRAGSRI 120
Query: 97 -----VATMRKLLSFGRRLGQALLSSMDQEYAGRGYHIRDWELRKIHRAAIKGDAAEVEH 151
VATMRKLLSFGRRLGQALLSSMDQEYAGRGYHIRDWELRKIHRAAIKGDAAEVEH
Sbjct: 121 LSYIAVATMRKLLSFGRRLGQALLSSMDQEYAGRGYHIRDWELRKIHRAAIKGDAAEVEH 180
Query: 152 CLTRRFRDLDVRDKKDRTVLHLACAHGRVQVVTLLLDRKCQINICDRLNRTPLMKAVHCQ 211
CLTRRFRDLDVRD+KDRTVLHLACAHGRVQVVTLLLDRKCQINICDRLNRTPLMKAVHCQ
Sbjct: 181 CLTRRFRDLDVRDRKDRTVLHLACAHGRVQVVTLLLDRKCQINICDRLNRTPLMKAVHCQ 240
Query: 212 EEACAIILLKRGANPNIKDIYGNTALHYAVYNEGTSLAERLLSHHANIEALNKEGNTPLL 271
EEACAIILLKRGANPNIKDIYGNTALHYAVYNEGTSLAERLLSHHANIEALNKEGNTPLL
Sbjct: 241 EEACAIILLKRGANPNIKDIYGNTALHYAVYNEGTSLAERLLSHHANIEALNKEGNTPLL 300
Query: 272 FAINSRRQHMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIHISSQDMF 331
FAINSRRQHMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIHISSQDMF
Sbjct: 301 FAINSRRQHMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIHISSQDMF 360
Query: 332 GQTAEDYAFCCDLRSIQQQILEHKNKMLKNHLRNDNQETAAMKPENLKKRKKRKKLKKRK 391
GQTAEDYAFCCDLRSIQQQILEHKNKMLKNHLRNDNQETAAMKPENLKKRKKRKKLKKRK
Sbjct: 361 GQTAEDYAFCCDLRSIQQQILEHKNKMLKNHLRNDNQETAAMKPENLKKRKKRKKLKKRK 420
Query: 392 EGAKAEHNLKVASEEKQERLERSENKQPQDSQSYGKKKDEMFGNFMLKRDIAMLKEELYA 451
EGAKAEHNLKVASEEKQERLERSENKQPQDSQSYGKKKDEMFGNFMLKRDIAMLKEELYA
Sbjct: 421 EGAKAEHNLKVASEEKQERLERSENKQPQDSQSYGKKKDEMFGNFMLKRDIAMLKEELYA 480
Query: 452 IKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEEMITKKVAQYSQQLNDLKAENARLNS 511
IKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEEMITKKVAQYSQQLNDLKAENARLNS
Sbjct: 481 IKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEEMITKKVAQYSQQLNDLKAENARLNS 540
Query: 512 KLEKEKHNKERLEAEVESLHSNLATAINEYNEILERKDLELVLWRADDVSRHETMGSNIS 571
KLEKEKHNKERLEAEVESLHSNLATAINEYNEILERKDLELVLWRADDVSRHETMGSNIS
Sbjct: 541 KLEKEKHNKERLEAEVESLHSNLATAINEYNEILERKDLELVLWRADDVSRHETMGSNIS 600
Query: 572 QLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKTLALESVQLDLKQAQHRIKEMKQ 631
QLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKTLALESVQLDLKQAQHRIKEMKQ
Sbjct: 601 QLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKTLALESVQLDLKQAQHRIKEMKQ 660
Query: 632 MHPNGEAKESQSIGKQNSSEERIRQRELENLLLERQLEDARKEGDNKEIVINIHRDCLEN 691
MHPNGEAKESQSIGKQNSSEERIRQRELENLLLERQLEDARKEGDNKEIVINIHRDCLEN
Sbjct: 661 MHPNGEAKESQSIGKQNSSEERIRQRELENLLLERQLEDARKEGDNKEIVINIHRDCLEN 720
Query: 692 GKEDLLEERNKELMNEYNYLKEKLLQYEKEKAEREVIVREFQEELVDHLKKFSMSESPLE 751
GKEDLLEERNKELMNEYNYLKEKLLQYEKEKAEREVIVREFQEELVDHLKKFSMSESPLE
Sbjct: 721 GKEDLLEERNKELMNEYNYLKEKLLQYEKEKAEREVIVREFQEELVDHLKKFSMSESPLE 780
Query: 752 GTSHCHINLDETWTSKKKLFQVEIQPEEKHEEFRKVFELISLLNYTADQIRKKNRELEEE 811
GTSHCHINLDETWTSKKKLFQVEIQPEEKHEEFRKVFELISLLNYTADQIRKKNRELEEE
Sbjct: 781 GTSHCHINLDETWTSKKKLFQVEIQPEEKHEEFRKVFELISLLNYTADQIRKKNRELEEE 840
Query: 812 ATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFDDLMAEKEAVSSK 871
ATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFDDLMAEKEAVSSK
Sbjct: 841 ATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFDDLMAEKEAVSSK 900
Query: 872 CVNLAKDNEVLHQELLSMGKVQEKCEKLEKDKKMLEEKVLNLKTHMEKDMVELGKVQEYK 931
CVNLAKDNEVLHQELLSMGKVQEKCEKLEKDKKMLEEKVLNLKTHMEKDMVELGKVQEYK
Sbjct: 901 CVNLAKDNEVLHQELLSMGKVQEKCEKLEKDKKMLEEKVLNLKTHMEKDMVELGKVQEYK 960
Query: 932 SELDERAMQAIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSKMKTA 991
SELDERAMQAIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSKMKTA
Sbjct: 961 SELDERAMQAIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSKMKTA 1020
Query: 992 YEDVTTELEEYKEAFAVALKANSSMSEKITKSDKKIAVISTKLFMEKERMEYFLSTLPMR 1051
YEDVTTELEEYKEAFAVALKANSSMSEKITKSDKKIAVISTKLFMEKERMEYFLSTLPMR
Sbjct: 1021 YEDVTTELEEYKEAFAVALKANSSMSEKITKSDKKIAVISTKLFMEKERMEYFLSTLPMR 1080
Query: 1052 PDPELPCVENLNSIELNRKYIPKMAIRIPTSNPQTSNNCKNSLTELLLRWALAPIYFLL 1110
PDPELPCVENLNSIELNRKYIPKMAIRIPTSNPQTSNNCKNSLTELLLRWALAPIYFLL
Sbjct: 1081 PDPELPCVENLNSIELNRKYIPKMAIRIPTSNPQTSNNCKNSLTELLLRWALAPIYFLL 1139
>gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1002
Score = 1848 bits (4788), Expect = 0.0
Identities = 943/1011 (93%), Positives = 977/1011 (96%), Gaps = 9/1011 (0%)
Query: 100 MRKLLSFGRRLGQALLSSMDQEYAGRGYHIRDWELRKIHRAAIKGDAAEVEHCLTRRFRD 159
MRKL SFGRRLGQALLSSMDQEYAG GY IRDWELRKIHRAAIKGDAAEVE CLTRRFRD
Sbjct: 1 MRKLFSFGRRLGQALLSSMDQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRD 60
Query: 160 LDVRDKKDRTVLHLACAHGRVQVVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAIIL 219
LD RD+KDRTVLHLACAHGRVQVVTLLL R+CQI+ICDRLNRTPLMKAVH QEEACAI+L
Sbjct: 61 LDARDRKDRTVLHLACAHGRVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVL 120
Query: 220 LKRGANPNIKDIYGNTALHYAVYNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQ 279
L+ GANPNI+DIYGNTALHYAVYN+GTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQ
Sbjct: 121 LECGANPNIEDIYGNTALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQ 180
Query: 280 HMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIHISSQDMFGQTAEDYA 339
HMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNI ISSQDMFGQTAEDYA
Sbjct: 181 HMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYA 240
Query: 340 FCCDLRSIQQQILEHKNKMLKNHLRNDNQETAAMKPENLKKRKKRKKLKKRKEGAKAEHN 399
C DLRSI+QQILEHKNKMLKNHLRNDNQETAAMKP NLKKRK+R AKAEHN
Sbjct: 241 LCSDLRSIRQQILEHKNKMLKNHLRNDNQETAAMKPANLKKRKER---------AKAEHN 291
Query: 400 LKVASEEKQERLERSENKQPQDSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSLRK 459
LKVASEEKQERL+RSENKQPQDSQSYGKKKD M+GNFMLK+DIAMLKEELYAIKNDSLRK
Sbjct: 292 LKVASEEKQERLQRSENKQPQDSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRK 351
Query: 460 EKKYIQEIKSITEINANFEKSVRLNEEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHN 519
EKKYIQEIKSITEINANFEKSVRLNE+MITK VA+YSQQLNDLKAENARLNS+LEKEKHN
Sbjct: 352 EKKYIQEIKSITEINANFEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHN 411
Query: 520 KERLEAEVESLHSNLATAINEYNEILERKDLELVLWRADDVSRHETMGSNISQLTDKNEL 579
KERLEAEVESLHS+LATAINEYNEI+ERKDLELVLWRADDVSRHE MGSNISQLTDKNEL
Sbjct: 412 KERLEAEVESLHSSLATAINEYNEIVERKDLELVLWRADDVSRHEKMGSNISQLTDKNEL 471
Query: 580 LTEQVHKARVKFNTLKGKLRETRDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAK 639
LTEQVHKARVKFNTLKGKLRETRDALREKTLAL SVQLDL+QAQHRIKEMKQMHPNGEAK
Sbjct: 472 LTEQVHKARVKFNTLKGKLRETRDALREKTLALGSVQLDLRQAQHRIKEMKQMHPNGEAK 531
Query: 640 ESQSIGKQNSSEERIRQRELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEE 699
ESQSIGKQNS EERIRQ+ELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEE
Sbjct: 532 ESQSIGKQNSLEERIRQQELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEE 591
Query: 700 RNKELMNEYNYLKEKLLQYEKEKAEREVIVREFQEELVDHLKKFSMSESPLEGTSHCHIN 759
RNKELM EYNYLKEKLLQ EKEKAEREVIVREFQEELVDHLK FS+SESPLEGTSHCHIN
Sbjct: 592 RNKELMKEYNYLKEKLLQCEKEKAEREVIVREFQEELVDHLKTFSISESPLEGTSHCHIN 651
Query: 760 LDETWTSKKKLFQVEIQPEEKHEEFRKVFELISLLNYTADQIRKKNRELEEEATGYKKCL 819
L+ETWTSKKKLFQVEIQPEEKHEEFRK+FELISLLNYTADQIRKKNRELEEEATGYKKCL
Sbjct: 652 LNETWTSKKKLFQVEIQPEEKHEEFRKLFELISLLNYTADQIRKKNRELEEEATGYKKCL 711
Query: 820 EMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFDDLMAEKEAVSSKCVNLAKDN 879
EMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKF+DL+AEKEAVSS+CVNLAKDN
Sbjct: 712 EMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSECVNLAKDN 771
Query: 880 EVLHQELLSMGKVQEKCEKLEKDKKMLEEKVLNLKTHMEKDMVELGKVQEYKSELDERAM 939
EVLHQELLSM VQEKCEKLEKDKKMLEE+VLNLKTHMEKDMVELGK+QEYKSELDERA+
Sbjct: 772 EVLHQELLSMRNVQEKCEKLEKDKKMLEEEVLNLKTHMEKDMVELGKLQEYKSELDERAV 831
Query: 940 QAIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSKMKTAYEDVTTEL 999
Q IEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSKMKTAYE+VTTEL
Sbjct: 832 QEIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSKMKTAYEEVTTEL 891
Query: 1000 EEYKEAFAVALKANSSMSEKITKSDKKIAVISTKLFMEKERMEYFLSTLPMRPDPELPCV 1059
EE+KEAFA A+KAN+SMS+K+ KSDKKIAVISTKLFMEKERMEYFLSTLPMRPDPELPCV
Sbjct: 892 EEFKEAFAGAVKANNSMSKKLMKSDKKIAVISTKLFMEKERMEYFLSTLPMRPDPELPCV 951
Query: 1060 ENLNSIELNRKYIPKMAIRIPTSNPQTSNNCKNSLTELLLRWALAPIYFLL 1110
ENLNSIELNRKYIPKMAIRIPTSNPQTSNNCKNSLTELLLRWALAPIYFLL
Sbjct: 952 ENLNSIELNRKYIPKMAIRIPTSNPQTSNNCKNSLTELLLRWALAPIYFLL 1002
>gi|154354990 ankyrin repeat domain 26 [Homo sapiens]
Length = 1710
Score = 555 bits (1429), Expect = e-157
Identities = 339/817 (41%), Positives = 494/817 (60%), Gaps = 88/817 (10%)
Query: 350 QILEHKNKMLKNHLRNDNQETAAMKPENLKKRKKRKKLKKRKEGAKAEHNLKVASEEKQE 409
Q LE + + +K++L QE + +++L + + + + KQ+
Sbjct: 838 QTLEMELRTVKSNLNQVVQE----------RNDAQRQLSREQNARMLQDGILTNHLSKQK 887
Query: 410 RLERSENKQ-PQDSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSLRKEKKYIQEIK 468
+E ++ K ++S S+ ++KD N ML+ +IAML+ E+ IKN + KEKK +++K
Sbjct: 888 EIEMAQKKMNSENSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLK 947
Query: 469 SITEINANFEKSVRLNEEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHNKERLEAEVE 528
+ E N + +K+++ NEE +T+ ++QY+ +L+ L AENA LNSKLE EK +KERLEAEVE
Sbjct: 948 IVKEKNEDLQKTIKQNEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVE 1007
Query: 529 SLHSNLATAINEYNEI-LERKDLELVLWRA-DDVSR-HETMGSNISQLTDKNELLTEQVH 585
S HS LA AI++ ++ +++LEL RA D+ SR + M ++S L D NE+L++Q+
Sbjct: 1008 SYHSRLAAAIHDRDQSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLF 1067
Query: 586 KARVKFNTLKGKLRETRDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAKESQSIG 645
K K N+L+ + TRDALREKTL LE VQ DL Q Q ++KEM+Q + N + K ++ IG
Sbjct: 1068 KTESKLNSLEIEFHHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIG 1127
Query: 646 KQNSSEERIRQRELENLLLERQLEDARKEGDNKE-IVINIHRDC--------LENGKEDL 696
KQ S EER+ Q + EN+LL +QL+DA + DNKE VINI E+ K+ L
Sbjct: 1128 KQESVEERLSQLQSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSL 1187
Query: 697 L-EERNKELMNEYNYLKEKLLQYEKEKAEREVIVREFQEELVDHL--------------- 740
L EERNKEL++E N+LKE+ QYE EKAEREV+VR+ Q+EL D L
Sbjct: 1188 LLEERNKELISECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSR 1247
Query: 741 -------------KKFSMSESPLEGTSHCHIN---------------------------- 759
KK + L+ H
Sbjct: 1248 YRINLEDETQDLKKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVTVKK 1307
Query: 760 -LDETWTSKKKLFQVEIQPEEKHEEFRKVFELISLLNYTADQIRKKNRELEEEATGYKKC 818
+D+ +K L + +EK E+ +K+ EL L DQ KKN ELE E TG+K
Sbjct: 1308 QMDKIEELQKNLLNANLSEDEK-EQLKKLMELKQSLECNLDQEMKKNVELEREITGFKNL 1366
Query: 819 LEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFDDLMAEKEAVSSKCVNLAKD 878
L+MT LN + N +FS HGDL T Q +MDI KLK K DDL AE E SKC++L
Sbjct: 1367 LKMTRKKLNEYENGEFSFHGDLKTSQFEMDIQINKLKHKIDDLTAELETAGSKCLHLDTK 1426
Query: 879 NEVLHQELLSMGKVQEKCEKLEKDKKMLEEKVLNLKTHMEKDMVELGKVQEYKSELDERA 938
N++L +ELLSM VQ+KCEKL+K+KK LE++V+NL++H+E++MVELG+V++YK E++ERA
Sbjct: 1427 NQILQEELLSMKTVQKKCEKLQKNKKKLEQEVINLRSHIERNMVELGQVKQYKQEIEERA 1486
Query: 939 MQAI-EKLEEIH--LQKQAEYEKQLEQLNKDNTASLKKK-ELTLKDVECKFSKMKTAYED 994
Q I EKL+E++ LQ QA ++ LEQ ++N AS+K + EL +KD+E + SK+KT+ ED
Sbjct: 1487 RQEIAEKLKEVNLFLQAQAASQENLEQFRENNFASMKSQMELRIKDLESELSKIKTSQED 1546
Query: 995 VT-TELEEYKEAFAVALKANSSMSEKITKSDKKIAVISTKLFMEKERMEYFLSTLPMRPD 1053
TELE+YK+ + LK S+S K+TK+++++A ++TKL +EK++ +TL RP
Sbjct: 1547 FNKTELEKYKQLYLEELKVRKSLSSKLTKTNERLAEVNTKLLVEKQQSRSLFTTLTTRPV 1606
Query: 1054 PELPCVENL-NSIELNRKYIPKMAIRIPTSNPQTSNN 1089
E PCV NL NS++LNRK IP+ + I TSNP+ SNN
Sbjct: 1607 MEPPCVGNLNNSLDLNRKLIPRENLVISTSNPRASNN 1643
Score = 219 bits (557), Expect = 2e-56
Identities = 105/185 (56%), Positives = 141/185 (76%)
Query: 122 YAGRGYHIRDWELRKIHRAAIKGDAAEVEHCLTRRFRDLDVRDKKDRTVLHLACAHGRVQ 181
Y+ GYH+RD +L KIH+AA G+ A+V+ L R L+ RDK +RT LHLACA+G +
Sbjct: 35 YSQPGYHVRDRDLGKIHKAASAGNVAKVQQILLLRKNGLNDRDKMNRTALHLACANGHPE 94
Query: 182 VVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAIILLKRGANPNIKDIYGNTALHYAV 241
VVTLL+DRKCQ+N+CD NRT LMKAV CQEE CA ILL+ GA+PN+ D++GNTALHYAV
Sbjct: 95 VVTLLVDRKCQLNVCDNENRTALMKAVQCQEEKCATILLEHGADPNLADVHGNTALHYAV 154
Query: 242 YNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNFKRT 301
YNE S+A +LL + ANIEA NK+ TPLL A++ ++Q MVEFL+K +AN++AVD + +
Sbjct: 155 YNEDISVATKLLLYDANIEAKNKDDLTPLLLAVSGKKQQMVEFLIKKKANVNAVDKLESS 214
Query: 302 ALILA 306
+++
Sbjct: 215 HQLIS 219
Score = 68.9 bits (167), Expect = 3e-11
Identities = 135/654 (20%), Positives = 264/654 (40%), Gaps = 96/654 (14%)
Query: 387 LKKRKEGAKAEHNLKVASEEKQERLERSENKQPQDSQSYGKKK----------------- 429
+K + AEH+L+VASEE+QER E SEN QPQ + K +
Sbjct: 513 MKDVQTSKAAEHDLEVASEEEQER-EGSENNQPQVEEERKKHRNNEMEVSANIHDGATDD 571
Query: 430 ---DEMFGNFMLKRDIAMLKEELYAIKNDSLRKEKK---------YIQEIKSITEINANF 477
D+ + KR + + RKE K ++E+KS +
Sbjct: 572 AEDDDDDDGLIQKRKSGETDHQQFP------RKENKEYASSGPALQMKEVKSTEKEKRTS 625
Query: 478 EKSVRL----NEEMITKKVAQYSQQ--LNDLKAENARLNSKLEKEKHN-KERLEA--EVE 528
++SV ++T + Q L+++ + R K EK+ K ++++ +V+
Sbjct: 626 KESVNSPVFGKASLLTGGLLQVDDDSSLSEIDEDEGRPTKKTSNEKNKVKNQIQSMDDVD 685
Query: 529 SLHSNLATAINE----------YNEILERKDLELVLWRADDVSRHETMGSNIS--QLTD- 575
L + TA + + ++E+ +E D VS + + +S +L +
Sbjct: 686 DLTQSSETASEDCELPHSSYKNFMLLIEQLGMEC----KDSVSLLKIQDAALSCERLLEL 741
Query: 576 -KN--ELLTEQVHKARVKFNTLKGKLRETRDALREKTLALESVQLDLKQAQHRIKEMKQM 632
KN ELLT ++ K K N L+ +L ET++ + + +L + + + ++
Sbjct: 742 KKNHCELLTVKIKKMEDKVNVLQRELSETKEIKSQLEHQKVEWERELCSLRFSLNQEEEK 801
Query: 633 HPNGEAKESQSIGKQNSSEERIRQRELENLLLERQLEDARKEGDNKEIVINIHRDCLENG 692
N + + + EE+ R+ LE L+ E + +N +
Sbjct: 802 RRNADTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQTLEMELRTVKSNLNQVVQERNDA 861
Query: 693 KEDLLEERNKELMNE---YNYL-KEKLLQYEKEKAEREVIVREFQEELVDHLKKFSMSES 748
+ L E+N ++ + N+L K+K ++ ++K E +E+ + H E
Sbjct: 862 QRQLSREQNARMLQDGILTNHLSKQKEIEMAQKKMNSENSHSHEEEKDLSHKNSMLQEEI 921
Query: 749 PLEGTSHCHINLDETWTSKKKLFQVEIQPEEKHEEFRKVF--------ELISLLNYTADQ 800
+ I ++ +KK F+ +EK+E+ +K + IS N
Sbjct: 922 AMLRLEIDTIK-NQNQEKEKKCFEDLKIVKEKNEDLQKTIKQNEETLTQTISQYNGRLSV 980
Query: 801 IRKKNRELE---EEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQK 857
+ +N L E K+ LE + ++ T + ++++ F++ +
Sbjct: 981 LTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHDRDQSETSKRELELAFQRAR-- 1038
Query: 858 FDDLMAEKEAVSSKCVNLAKDNEVLHQELLSMGKVQEKCEKLEKD----KKMLEEKVLNL 913
D+ ++ ++ NL +NE+L Q+L K + K LE + + L EK L L
Sbjct: 1039 -DECSRLQDKMNFDVSNLKDNNEILSQQLF---KTESKLNSLEIEFHHTRDALREKTLGL 1094
Query: 914 KTHMEKDMVELGKVQEYKSELDERAMQAIEKLEEIHLQKQAEYEKQLEQLNKDN 967
E+ +L + Q E++++ K+ + ++ KQ E++L QL +N
Sbjct: 1095 ----ERVQKDLSQTQCQMKEMEQKYQNEQVKVNK-YIGKQESVEERLSQLQSEN 1143
Score = 50.1 bits (118), Expect = 1e-05
Identities = 100/502 (19%), Positives = 199/502 (39%), Gaps = 91/502 (18%)
Query: 344 LRSIQQQILE--HKNKMLKNHLRNDNQETAAMKPENLKKRKKRKKLKKRKEGAKAEHNLK 401
+R +QQ++ + K M + L ++ ++ E +KK +++ + + A+ H
Sbjct: 1221 VRQLQQELADTLKKQSMSEASLEVTSRYRINLEDETQDLKKKLGQIRNQLQEAQDRHTEA 1280
Query: 402 VASEEK-QERLERSENKQPQDSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSLRKE 460
V EK Q+ ++ E + + K+ D++ + K L A ++ +++
Sbjct: 1281 VRCAEKMQDHKQKLEKDNAKLKVTVKKQMDKIE---------ELQKNLLNANLSEDEKEQ 1331
Query: 461 KKYIQEIKSITEINANFE--KSVRLNEE---------MITKKVAQYSQQL----NDLKAE 505
K + E+K E N + E K+V L E M KK+ +Y DLK
Sbjct: 1332 LKKLMELKQSLECNLDQEMKKNVELEREITGFKNLLKMTRKKLNEYENGEFSFHGDLKTS 1391
Query: 506 NARLNSKLEKEKHNKERLEAEVESLHSNLATAINEYNEILERKDLELVLWRADDVSRHET 565
++ ++ K KH + L AE+E+ S ++ N+IL+ + L + + + E
Sbjct: 1392 QFEMDIQINKLKHKIDDLTAELETAGSK-CLHLDTKNQILQEELLSMKTVQ----KKCEK 1446
Query: 566 MGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKTLA-LESVQLDLKQAQH 624
+ N +L + L + + V+ +K +E + R++ L+ V L L+
Sbjct: 1447 LQKNKKKLEQEVINLRSHIERNMVELGQVKQYKQEIEERARQEIAEKLKEVNLFLQAQAA 1506
Query: 625 RIKEMKQMHPNGEAK------------ESQSIGKQNSSE-------ERIRQRELENLLLE 665
+ ++Q N A ES+ + S E E+ +Q LE L +
Sbjct: 1507 SQENLEQFRENNFASMKSQMELRIKDLESELSKIKTSQEDFNKTELEKYKQLYLEELKVR 1566
Query: 666 RQLEDARKEGDNKEIVIN----------------------IHRDCLENGKEDLLEERNKE 703
+ L + + + +N + C+ N L + N++
Sbjct: 1567 KSLSSKLTKTNERLAEVNTKLLVEKQQSRSLFTTLTTRPVMEPPCVGNLNNSL--DLNRK 1624
Query: 704 LMNEYNYL------------KEKLLQYEKEKAEREVIVREFQEELVDHLKKFSMSESPLE 751
L+ N + E L +++ E+ I RE +E + L+ S++ SPL
Sbjct: 1625 LIPRENLVISTSNPRASNNSMENYLSKMQQELEKN-ITRELKEAAAE-LESGSIA-SPLG 1681
Query: 752 GTSHCHINLDETWTSKKKLFQV 773
T ++N D W + ++ QV
Sbjct: 1682 STDESNLNQDLVWKASREYVQV 1703
Score = 45.4 bits (106), Expect = 4e-04
Identities = 50/216 (23%), Positives = 83/216 (38%), Gaps = 18/216 (8%)
Query: 218 ILLKRGANPNIKDIYGNTALHYAVYNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSR 277
ILL R N +D TALH A N + L+ + + E T L+ A+ +
Sbjct: 65 ILLLRKNGLNDRDKMNRTALHLACANGHPEVVTLLVDRKCQLNVCDNENRTALMKAVQCQ 124
Query: 278 RQHMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVT--LLLQQNIHISSQDMFGQTA 335
+ LL++ A+ + D TAL AV + S+ T LL NI ++D
Sbjct: 125 EEKCATILLEHGADPNLADVHGNTALHYAVYNEDISVATKLLLYDANIEAKNKD------ 178
Query: 336 EDYAFCCDLRSIQQQILEHKNKMLKNHLRNDNQETAAMKPENLKKRKKRKKLKKRKEGAK 395
DL + + K +M++ ++ A K E+ + + K+ +
Sbjct: 179 -------DLTPLLLAVSGKKQQMVEFLIKKKANVNAVDKLES--SHQLISEYKEERIPKH 229
Query: 396 AEHNLKVASEEKQERLERSENKQPQDSQSYGKKKDE 431
+ N E ++ L R K P S+ DE
Sbjct: 230 SSQNSNSVDESSEDSLSRLSGK-PGVDDSWPTSDDE 264
Score = 31.6 bits (70), Expect = 5.4
Identities = 21/72 (29%), Positives = 33/72 (45%)
Query: 283 EFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIHISSQDMFGQTAEDYAFCC 342
+ LL + ++ D RTAL LA + +VTLL+ + ++ D +TA A C
Sbjct: 64 QILLLRKNGLNDRDKMNRTALHLACANGHPEVVTLLVDRKCQLNVCDNENRTALMKAVQC 123
Query: 343 DLRSIQQQILEH 354
+LEH
Sbjct: 124 QEEKCATILLEH 135
Score = 30.8 bits (68), Expect = 9.3
Identities = 38/180 (21%), Positives = 75/180 (41%), Gaps = 17/180 (9%)
Query: 859 DDLMAEKEAVSSKCV--NLAKDNEVLHQELLSMGKVQEKCEKLE-KDKKMLEEKVLNLK- 914
DDL E S C + + N +L E L M + ++ L+ +D + E++L LK
Sbjct: 685 DDLTQSSETASEDCELPHSSYKNFMLLIEQLGM-ECKDSVSLLKIQDAALSCERLLELKK 743
Query: 915 THMEKDMVELGKVQEYKSELDERAMQAIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKK 974
H E V++ K+++ + L + E ++ QK E+E++L L
Sbjct: 744 NHCELLTVKIKKMEDKVNVLQRELSETKEIKSQLEHQK-VEWERELCSLR---------- 792
Query: 975 ELTLKDVECKFSKMKTAYEDVTTELEEYKEAFAVALKANSSMSEKITKSDKKIAVISTKL 1034
+L E K T YE + +L +E + ++ + + + ++ + + L
Sbjct: 793 -FSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQTLEMELRTVKSNL 851
>gi|60115723 ankyrin repeat domain 20 family, member A2 [Homo
sapiens]
Length = 823
Score = 379 bits (972), Expect = e-104
Identities = 270/791 (34%), Positives = 392/791 (49%), Gaps = 142/791 (17%)
Query: 102 KLLSFGRRLGQALLSSMDQEYAGRGYHIRDWELRKIHRAAIKGDAAEVEHCLTRRFRDLD 161
KL FG R GQ S+D Y G GY IRD EL+KIHRAA+KGDAAEVE CL RR DLD
Sbjct: 2 KLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDLD 61
Query: 162 VRDKKDRTVLHLACAHGRVQVVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAIILLK 221
DK+ RT LHLACA G VQVVTLL++RKCQI++CD+ NRTPL++AVHCQEEACA+ILL+
Sbjct: 62 ALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLE 121
Query: 222 RGANPNIKDIYGNTALHYAVYNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHM 281
GANPN+KDIYGNTALHYAVY+E TSLAE+LLSH A+IEAL+K+ NTPLLFAI +++ M
Sbjct: 122 HGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKM 181
Query: 282 VEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIHISSQDMFGQTAEDYAFC 341
VEFLLK +A+ HAVD +R+AL+LAV ++ IV +LL+QNI + +QDM G+ AEDYA
Sbjct: 182 VEFLLKRKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAIS 241
Query: 342 CDLRSIQQQILEHKNKMLK-----------------NHLRND----------NQETAAMK 374
L IQQQILEHK K+LK + LR D N T
Sbjct: 242 HHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQCV 301
Query: 375 PENLKK-------RKKRKKLKKRKEGAKAEH----------------------------- 398
PE + + K + + + EG A+H
Sbjct: 302 PEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAE 361
Query: 399 -NLKVASEEKQERLERSENKQPQDSQSYGKKKDEMF---------------GNFMLKRDI 442
L VASEE+QER ERSE KQPQ + K E G +R I
Sbjct: 362 QALPVASEEEQERHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRKI 421
Query: 443 AMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEEMITKKVAQYSQQLN-- 500
+ + K QE + T +N ++K N E + +K QY +++
Sbjct: 422 GKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLYKK----NREELERKEKQYKKEVEAK 477
Query: 501 ---------DLKAENARLNSKLEKEKHNKER--------LEAEVESLHSNLATAINEYNE 543
++K++ AR + H + + L+A++ L + T N+ E
Sbjct: 478 QLEPTVQSLEMKSKTARNTPNRDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLE 537
Query: 544 ILER--KDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRET 601
+ KD+++V ET + + E++TE + + + N LK +
Sbjct: 538 KENKYLKDIKIV---------KETNAALEKYIKLNEEMITETAFRYQQELNDLKAENTRL 588
Query: 602 RDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAKE---------SQSIGKQNSSEE 652
L ++ + + ++ D++ Q R+ H E ++ + Q
Sbjct: 589 NAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKTERNLKLALERTRDVSVQVEMSS 648
Query: 653 RIRQRELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKELMNEYNYLK 712
I + + EN L QL + +I N +D ++ L R K L E ++
Sbjct: 649 AISKVKDENEFLTEQLSET-------QIKFNALKDKFRKTRDSL---RKKSLALE--TVQ 696
Query: 713 EKLLQYEKEKAEREVIVREFQEELVDHLKKFSMSESPLEGTSHCHINLDETWTSKKKLFQ 772
L Q +++ E + + + + ++ + K++ E + CH+ + W ++
Sbjct: 697 NDLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERI-----CHLQRENAWLVQQ---L 748
Query: 773 VEIQPEEKHEE 783
++ +E H+E
Sbjct: 749 DDVHQKEDHKE 759
Score = 308 bits (789), Expect = 2e-83
Identities = 170/374 (45%), Positives = 258/374 (68%), Gaps = 8/374 (2%)
Query: 363 LRNDNQETAAMKPENLKKRKKRKKLKKRKEGAKAE---HNLKVASEEKQERLERSENKQP 419
L+ +N+E + N+ +K R++L+++++ K E L+ + + + + + N
Sbjct: 442 LKQENEEKTNV---NMLYKKNREELERKEKQYKKEVEAKQLEPTVQSLEMKSKTARNTPN 498
Query: 420 QDSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEK 479
+D ++ + K M N +LK DIA+L++E+ +KND+L KE KY+++IK + E NA EK
Sbjct: 499 RDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEK 558
Query: 480 SVRLNEEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHNKERLEAEVESLHSNLATAIN 539
++LNEEMIT+ +Y Q+LNDLKAEN RLN++L KEK +K+RLEA++ES S LA AI+
Sbjct: 559 YIKLNEEMITETAFRYQQELNDLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAIS 618
Query: 540 EYNEILE-RKDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKARVKFNTLKGKL 598
+++E ++ ++L+L L R DVS M S IS++ D+NE LTEQ+ + ++KFN LK K
Sbjct: 619 KHSESVKTERNLKLALERTRDVSVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKDKF 678
Query: 599 RETRDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAKESQSIGKQNSSEERIRQRE 658
R+TRD+LR+K+LALE+VQ DL Q Q + +EMK+M+ N EAK + S GK N EERI +
Sbjct: 679 RKTRDSLRKKSLALETVQNDLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHLQ 738
Query: 659 LENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDL-LEERNKELMNEYNYLKEKLLQ 717
EN L +QL+D ++ D+KEIV NI R +E+GK+DL LEE++K+LMNE ++LKE L Q
Sbjct: 739 RENAWLVQQLDDVHQKEDHKEIVTNIQRGFIESGKKDLVLEEKSKKLMNECDHLKESLFQ 798
Query: 718 YEKEKAEREVIVRE 731
YE+EK E V ++E
Sbjct: 799 YEREKTEGVVSIKE 812
>gi|60460920 ankyrin repeat domain 20 family, member A3 [Homo
sapiens]
Length = 823
Score = 378 bits (971), Expect = e-104
Identities = 270/791 (34%), Positives = 392/791 (49%), Gaps = 142/791 (17%)
Query: 102 KLLSFGRRLGQALLSSMDQEYAGRGYHIRDWELRKIHRAAIKGDAAEVEHCLTRRFRDLD 161
KL FG R GQ S+D Y G GY IRD EL+KIHRAA+KGDAAEVE CL RR DLD
Sbjct: 2 KLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDLD 61
Query: 162 VRDKKDRTVLHLACAHGRVQVVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAIILLK 221
DK+ RT LHLACA G VQVVTLL++RKCQI++CD+ NRTPL++AVHCQEEACA+ILL+
Sbjct: 62 ALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLE 121
Query: 222 RGANPNIKDIYGNTALHYAVYNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHM 281
GANPN+KDIYGNTALHYAVY+E TSLAE+LLSH A+IEAL+K+ NTPLLFAI +++ M
Sbjct: 122 HGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKM 181
Query: 282 VEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIHISSQDMFGQTAEDYAFC 341
VEFLLK +A+ HAVD +R+AL+LAV ++ IV +LL+QNI + +QDM G+ AEDYA
Sbjct: 182 VEFLLKRKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAIS 241
Query: 342 CDLRSIQQQILEHKNKMLK-----------------NHLRND----------NQETAAMK 374
L IQQQILEHK K+LK + LR D N T
Sbjct: 242 HHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQCV 301
Query: 375 PENLKK-------RKKRKKLKKRKEGAKAEH----------------------------- 398
PE + + K + + + EG A+H
Sbjct: 302 PEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAE 361
Query: 399 -NLKVASEEKQERLERSENKQPQDSQSYGKKKDEMF---------------GNFMLKRDI 442
L VASEE+QER ERSE KQPQ + K E G +R I
Sbjct: 362 QALPVASEEEQERHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRKI 421
Query: 443 AMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEEMITKKVAQYSQQLN-- 500
+ + K QE + T +N ++K N E + +K QY +++
Sbjct: 422 GKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLYKK----NREELERKEKQYKKEVEAK 477
Query: 501 ---------DLKAENARLNSKLEKEKHNKER--------LEAEVESLHSNLATAINEYNE 543
++K++ AR + H + + L+A++ L + T N+ E
Sbjct: 478 QLEPTVQSLEMKSKTARNTPNRDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLE 537
Query: 544 ILER--KDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRET 601
+ KD+++V ET + + E++TE + + + N LK +
Sbjct: 538 KENKYLKDIKIV---------KETNAALEKYIKLNEEMITETAFRYQQELNYLKAENTRL 588
Query: 602 RDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAKE---------SQSIGKQNSSEE 652
L ++ + + ++ D++ Q R+ H E ++ + Q
Sbjct: 589 NAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKTERNLKLALERTRDVSVQVEMSS 648
Query: 653 RIRQRELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKELMNEYNYLK 712
I + + EN L QL + +I N +D ++ L R K L E ++
Sbjct: 649 AISKVKDENEFLTEQLSET-------QIKFNALKDKFRKTRDSL---RKKSLALE--TVQ 696
Query: 713 EKLLQYEKEKAEREVIVREFQEELVDHLKKFSMSESPLEGTSHCHINLDETWTSKKKLFQ 772
L Q +++ E + + + + ++ + K++ E + CH+ + W ++
Sbjct: 697 NDLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERI-----CHLQRENAWLVQQ---L 748
Query: 773 VEIQPEEKHEE 783
++ +E H+E
Sbjct: 749 DDVHQKEDHKE 759
Score = 305 bits (780), Expect = 3e-82
Identities = 169/374 (45%), Positives = 257/374 (68%), Gaps = 8/374 (2%)
Query: 363 LRNDNQETAAMKPENLKKRKKRKKLKKRKEGAKAE---HNLKVASEEKQERLERSENKQP 419
L+ +N+E + N+ +K R++L+++++ K E L+ + + + + + N
Sbjct: 442 LKQENEEKTNV---NMLYKKNREELERKEKQYKKEVEAKQLEPTVQSLEMKSKTARNTPN 498
Query: 420 QDSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEK 479
+D ++ + K M N +LK DIA+L++E+ +KND+L KE KY+++IK + E NA EK
Sbjct: 499 RDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEK 558
Query: 480 SVRLNEEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHNKERLEAEVESLHSNLATAIN 539
++LNEEMIT+ +Y Q+LN LKAEN RLN++L KEK +K+RLEA++ES S LA AI+
Sbjct: 559 YIKLNEEMITETAFRYQQELNYLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAIS 618
Query: 540 EYNEILE-RKDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKARVKFNTLKGKL 598
+++E ++ ++L+L L R DVS M S IS++ D+NE LTEQ+ + ++KFN LK K
Sbjct: 619 KHSESVKTERNLKLALERTRDVSVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKDKF 678
Query: 599 RETRDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAKESQSIGKQNSSEERIRQRE 658
R+TRD+LR+K+LALE+VQ DL Q Q + +EMK+M+ N EAK + S GK N EERI +
Sbjct: 679 RKTRDSLRKKSLALETVQNDLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHLQ 738
Query: 659 LENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDL-LEERNKELMNEYNYLKEKLLQ 717
EN L +QL+D ++ D+KEIV NI R +E+GK+DL LEE++K+LMNE ++LKE L Q
Sbjct: 739 RENAWLVQQLDDVHQKEDHKEIVTNIQRGFIESGKKDLVLEEKSKKLMNECDHLKESLFQ 798
Query: 718 YEKEKAEREVIVRE 731
YE+EK E V ++E
Sbjct: 799 YEREKTEGVVSIKE 812
>gi|156104901 ankyrin repeat domain 20 family, member A1 [Homo
sapiens]
Length = 823
Score = 378 bits (971), Expect = e-104
Identities = 269/791 (34%), Positives = 391/791 (49%), Gaps = 142/791 (17%)
Query: 102 KLLSFGRRLGQALLSSMDQEYAGRGYHIRDWELRKIHRAAIKGDAAEVEHCLTRRFRDLD 161
KL FG R GQ S+D Y G GY IRD EL+KIHRAA+KGDAAEVE CL RR DLD
Sbjct: 2 KLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDLD 61
Query: 162 VRDKKDRTVLHLACAHGRVQVVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAIILLK 221
DK+ RT LHLAC G VQVVTLL++RKCQI++CD+ NRTPL++AVHCQEEACA+ILL+
Sbjct: 62 ALDKQHRTALHLACTSGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLE 121
Query: 222 RGANPNIKDIYGNTALHYAVYNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHM 281
GANPN+KDIYGNTALHYAVY+E TSLAE+LLSH A+IEAL+K+ NTPLLFAI +++ M
Sbjct: 122 HGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKM 181
Query: 282 VEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIHISSQDMFGQTAEDYAFC 341
VEFLLK +A+ HAVD +R+AL+LAV ++ IV +LL+QNI + +QDM G+ AEDYA
Sbjct: 182 VEFLLKKKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAIS 241
Query: 342 CDLRSIQQQILEHKNKMLK-----------------NHLRND----------NQETAAMK 374
L IQQQILEHK K+LK + LR D N T
Sbjct: 242 HHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQCV 301
Query: 375 PENLKK-------RKKRKKLKKRKEGAKAEH----------------------------- 398
PE + + K + + + EG A+H
Sbjct: 302 PEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAE 361
Query: 399 -NLKVASEEKQERLERSENKQPQDSQSYGKKKDEMF---------------GNFMLKRDI 442
L VASEE+QER ERSE KQPQ + K E G +R I
Sbjct: 362 QALPVASEEEQERHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRKI 421
Query: 443 AMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEEMITKKVAQYSQQLN-- 500
+ + K QE + T +N ++K N E + +K QY +++
Sbjct: 422 GKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLYKK----NREELERKEKQYKKEVEAK 477
Query: 501 ---------DLKAENARLNSKLEKEKHNKER--------LEAEVESLHSNLATAINEYNE 543
++K++ AR + H + + L+A++ L + T N+ E
Sbjct: 478 QLEPTVQSLEMKSKTARNTPNWDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLE 537
Query: 544 ILER--KDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRET 601
+ KD+++V ET + + E++TE + + + N LK +
Sbjct: 538 KENKYLKDIKIV---------KETNAALEKYIKLNEEMITETAFRYQQELNDLKAENTRL 588
Query: 602 RDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAKE---------SQSIGKQNSSEE 652
L ++ + + ++ D++ Q R+ H E ++ + Q
Sbjct: 589 NAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKTERNLKLALERTRDVSVQVEMSS 648
Query: 653 RIRQRELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKELMNEYNYLK 712
I + + EN L QL + +I N +D ++ L R K L E ++
Sbjct: 649 AISKVKAENEFLTEQLSET-------QIKFNALKDKFRKTRDSL---RKKSLALE--TVQ 696
Query: 713 EKLLQYEKEKAEREVIVREFQEELVDHLKKFSMSESPLEGTSHCHINLDETWTSKKKLFQ 772
L Q +++ E + + + + ++ + K++ E + CH+ + W ++
Sbjct: 697 NDLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERI-----CHLQRENAWLVQQ---L 748
Query: 773 VEIQPEEKHEE 783
++ +E H+E
Sbjct: 749 DDVHQKEDHKE 759
Score = 304 bits (778), Expect = 4e-82
Identities = 169/374 (45%), Positives = 256/374 (68%), Gaps = 8/374 (2%)
Query: 363 LRNDNQETAAMKPENLKKRKKRKKLKKRKEGAKAE---HNLKVASEEKQERLERSENKQP 419
L+ +N+E + N+ +K R++L+++++ K E L+ + + + + + N
Sbjct: 442 LKQENEEKTNV---NMLYKKNREELERKEKQYKKEVEAKQLEPTVQSLEMKSKTARNTPN 498
Query: 420 QDSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEK 479
D ++ + K M N +LK DIA+L++E+ +KND+L KE KY+++IK + E NA EK
Sbjct: 499 WDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEK 558
Query: 480 SVRLNEEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHNKERLEAEVESLHSNLATAIN 539
++LNEEMIT+ +Y Q+LNDLKAEN RLN++L KEK +K+RLEA++ES S LA AI+
Sbjct: 559 YIKLNEEMITETAFRYQQELNDLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAIS 618
Query: 540 EYNEILE-RKDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKARVKFNTLKGKL 598
+++E ++ ++L+L L R DVS M S IS++ +NE LTEQ+ + ++KFN LK K
Sbjct: 619 KHSESVKTERNLKLALERTRDVSVQVEMSSAISKVKAENEFLTEQLSETQIKFNALKDKF 678
Query: 599 RETRDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAKESQSIGKQNSSEERIRQRE 658
R+TRD+LR+K+LALE+VQ DL Q Q + +EMK+M+ N EAK + S GK N EERI +
Sbjct: 679 RKTRDSLRKKSLALETVQNDLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHLQ 738
Query: 659 LENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDL-LEERNKELMNEYNYLKEKLLQ 717
EN L +QL+D ++ D+KEIV NI R +E+GK+DL LEE++K+LMNE ++LKE L Q
Sbjct: 739 RENAWLVQQLDDVHQKEDHKEIVTNIQRGFIESGKKDLVLEEKSKKLMNECDHLKESLFQ 798
Query: 718 YEKEKAEREVIVRE 731
YE+EK E V ++E
Sbjct: 799 YEREKTEGVVSIKE 812
>gi|149363679 ankyrin repeat domain 20 family, member A4 [Homo
sapiens]
Length = 823
Score = 378 bits (970), Expect = e-104
Identities = 269/791 (34%), Positives = 392/791 (49%), Gaps = 142/791 (17%)
Query: 102 KLLSFGRRLGQALLSSMDQEYAGRGYHIRDWELRKIHRAAIKGDAAEVEHCLTRRFRDLD 161
KL FG R GQ S+D Y G GY IRD EL+KIHRAA+KGDAAEVE CL RR +LD
Sbjct: 2 KLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGELD 61
Query: 162 VRDKKDRTVLHLACAHGRVQVVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAIILLK 221
DK+ RT LHLACA G VQVVTLL++RKCQI++CD+ NRTPL++AVHCQEEACA+ILL+
Sbjct: 62 ALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLE 121
Query: 222 RGANPNIKDIYGNTALHYAVYNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHM 281
GANPN+KDIYGNTALHYAVY+E TSLAE+LLSH A+IEAL+K+ NTPLLFAI +++ M
Sbjct: 122 HGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKM 181
Query: 282 VEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIHISSQDMFGQTAEDYAFC 341
VEFLLK +A+ HAVD +R+AL+LAV ++ IV +LL+QNI + +QDM G+ AEDYA
Sbjct: 182 VEFLLKKKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAIS 241
Query: 342 CDLRSIQQQILEHKNKMLK-----------------NHLRND----------NQETAAMK 374
L IQQQILEHK K+LK + LR D N T
Sbjct: 242 HHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQCV 301
Query: 375 PENLKK-------RKKRKKLKKRKEGAKAEH----------------------------- 398
PE + + K + + + EG A+H
Sbjct: 302 PEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAE 361
Query: 399 -NLKVASEEKQERLERSENKQPQDSQSYGKKKDEMF---------------GNFMLKRDI 442
L VASEE+Q+R ERSE KQPQ + K E G +R I
Sbjct: 362 QALPVASEEEQQRHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRKI 421
Query: 443 AMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEEMITKKVAQYSQQLN-- 500
+ + K QE + T +N ++K N E + +K QY +++
Sbjct: 422 GKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLYKK----NREELERKEKQYKKEVEAK 477
Query: 501 ---------DLKAENARLNSKLEKEKHNKER--------LEAEVESLHSNLATAINEYNE 543
++K++ AR + H + + L+A++ L + T N+ E
Sbjct: 478 QLEPTVQSLEMKSKTARNTPNWDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLE 537
Query: 544 ILER--KDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRET 601
+ KD+++V ET + + E++TE + + + N LK +
Sbjct: 538 KENKYLKDIKIV---------KETNAALEKYIKLNEEMITETAFRYQQELNDLKAENTRL 588
Query: 602 RDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAKE---------SQSIGKQNSSEE 652
L ++ + + ++ D++ Q R+ H E +Q + Q
Sbjct: 589 NAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKTERNLKLALERTQDVSVQVEMSS 648
Query: 653 RIRQRELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKELMNEYNYLK 712
I + + EN L QL + +I N +D ++ L R K L E ++
Sbjct: 649 AISKVKDENEFLTEQLSET-------QIKFNALKDKFRKTRDSL---RKKSLALE--TVQ 696
Query: 713 EKLLQYEKEKAEREVIVREFQEELVDHLKKFSMSESPLEGTSHCHINLDETWTSKKKLFQ 772
L Q +++ E + + + + ++ + K++ E + CH+ + W ++
Sbjct: 697 NNLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERI-----CHLQRENAWLVQQ---L 748
Query: 773 VEIQPEEKHEE 783
++ +E H+E
Sbjct: 749 DDVHQKEDHKE 759
Score = 304 bits (779), Expect = 3e-82
Identities = 168/374 (44%), Positives = 257/374 (68%), Gaps = 8/374 (2%)
Query: 363 LRNDNQETAAMKPENLKKRKKRKKLKKRKEGAKAE---HNLKVASEEKQERLERSENKQP 419
L+ +N+E + N+ +K R++L+++++ K E L+ + + + + + N
Sbjct: 442 LKQENEEKTNV---NMLYKKNREELERKEKQYKKEVEAKQLEPTVQSLEMKSKTARNTPN 498
Query: 420 QDSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEK 479
D ++ + K M N +LK DIA+L++E+ +KND+L KE KY+++IK + E NA EK
Sbjct: 499 WDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEK 558
Query: 480 SVRLNEEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHNKERLEAEVESLHSNLATAIN 539
++LNEEMIT+ +Y Q+LNDLKAEN RLN++L KEK +K+RLEA++ES S LA AI+
Sbjct: 559 YIKLNEEMITETAFRYQQELNDLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAIS 618
Query: 540 EYNEILE-RKDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKARVKFNTLKGKL 598
+++E ++ ++L+L L R DVS M S IS++ D+NE LTEQ+ + ++KFN LK K
Sbjct: 619 KHSESVKTERNLKLALERTQDVSVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKDKF 678
Query: 599 RETRDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAKESQSIGKQNSSEERIRQRE 658
R+TRD+LR+K+LALE+VQ +L Q Q + +EMK+M+ N EAK + S GK N EERI +
Sbjct: 679 RKTRDSLRKKSLALETVQNNLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHLQ 738
Query: 659 LENLLLERQLEDARKEGDNKEIVINIHRDCLENGKED-LLEERNKELMNEYNYLKEKLLQ 717
EN L +QL+D ++ D+KEIV NI R +E+GK+D +LEE++K+LMNE ++LKE L Q
Sbjct: 739 RENAWLVQQLDDVHQKEDHKEIVTNIQRGFIESGKKDFVLEEKSKKLMNECDHLKESLFQ 798
Query: 718 YEKEKAEREVIVRE 731
YE+EK E V ++E
Sbjct: 799 YEREKTEVVVSIKE 812
>gi|239757009 PREDICTED: ankyrin repeat domain 20 family, member A5
[Homo sapiens]
Length = 823
Score = 358 bits (918), Expect = 3e-98
Identities = 271/805 (33%), Positives = 396/805 (49%), Gaps = 120/805 (14%)
Query: 102 KLLSFGRRLGQALLSSMDQEYAGRGYHIRDWELRKIHRAAIKGDAAEVEHCLTRRFRDLD 161
KL F R GQ +L S+D Y G GY IR EL+KIH+AA+KGDAAE+E CL RR DLD
Sbjct: 2 KLFGFRSRRGQTVLGSIDHLYTGSGYRIRYSELQKIHKAAVKGDAAEMERCLARRSGDLD 61
Query: 162 VRDKKDRTVLHLACAHGRVQVVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAIILLK 221
DK+ RT LHLACA G V+VVTLL++RKCQI+I D+ NRTPL++AVHCQEEACA+ILL+
Sbjct: 62 ALDKQHRTALHLACASGHVKVVTLLVNRKCQIDIYDKENRTPLIQAVHCQEEACAVILLE 121
Query: 222 RGANPNIKDIYGNTALHYAVYNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHM 281
GANPN+KDIYGNTALHYAVY+E TSLAE+LL H NIEAL+K+ NTPLLFAI +++ M
Sbjct: 122 HGANPNLKDIYGNTALHYAVYSESTSLAEKLLFHGENIEALDKDSNTPLLFAIICKKEKM 181
Query: 282 VEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIHISSQDMFGQTAEDYAFC 341
VEFLLKN+A+ HAVD + TAL+LAV ++ IV +LL+Q+I++ +QDM G+ AEDYA
Sbjct: 182 VEFLLKNKASTHAVDRLRXTALMLAVHYDSLGIVNILLKQSINVFTQDMCGRDAEDYAIS 241
Query: 342 CDLRSIQQQILEHKNKMLKN------------------------HLRNDNQETAAMK--- 374
C L IQQQILEHK +LKN +D + A K
Sbjct: 242 CRLTKIQQQILEHKKMILKNDKPDVGSSDESAVSIFHELCVDSLSALDDELLSVAAKQCV 301
Query: 375 PENLKK-------RKKRKKLKKRKEGAKAEH-NLKVASE--------------------- 405
PE + + K + + + EG A+H +LK ++E
Sbjct: 302 PEKVSEPLRGPSHGKGNRIVNGKGEGPPAKHPSLKPSTEMEDPAVKGAVQXKNVQTLRAE 361
Query: 406 --------EKQERLERSENKQPQDSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSL 457
E+Q+R ERSE KQPQ + K E L +I ++ D L
Sbjct: 362 QALPVASEEEQQRRERSEKKQPQVIEGNNTYKSE---KIQLSENIC---HSTFSAAADRL 415
Query: 458 RKEKKYIQEIKSITEINANFEKSVRLNEEMITKKVAQYSQQLNDLKAENARLNSKLE-KE 516
+++K + F K ++ + T K Q +++ ++ + + +LE KE
Sbjct: 416 TQQRKIGKTYPQ------QFPKKLKEEHDRCTLK--QENEEKTNVNMLHKKNREELERKE 467
Query: 517 KHNKERLEAE-----VESLHSNLATAIN-------EYNEILERKDLELVLWRADDVSRHE 564
K K+ +EA+ V+SL TA N + E+ + D +L + R E
Sbjct: 468 KQYKKEVEAKQLEPTVQSLEMKPKTARNTPNQDFHNHEEVKDLMDENCILKTDIAILRQE 527
Query: 565 TMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKTLALESVQL-DLKQAQ 623
L +N+ L + K + N K + + + KT +L DLK
Sbjct: 528 ICTMKNDNLEKENKYLKD--IKIAKETNAALEKCIKLNEEMITKTAFWYQQELNDLKAEN 585
Query: 624 HRIKEMKQMHPNGEAKESQSIGKQNSSEERIRQRELENLLLERQLEDARKEGDNKEIVIN 683
R+ + K I S + EN+ ER L+ A + + +
Sbjct: 586 TRLNSELLKEKESKKKLEAEIESYQSRLAAAISKHSENVKTERNLKLALERTQDISEQVK 645
Query: 684 IHRDCLE-NGKEDLLEERNKELMNEYNYLKEKLLQYEKEKAEREVIVREFQEEL------ 736
+ D E K L E+ ++ ++N LK+K + ++ + + Q +L
Sbjct: 646 MSSDISEIEDKNXFLTEQLSKMQIKFNTLKDKFRKTRDTLRKKSLALETVQNDLSQTQQQ 705
Query: 737 VDHLKKFSMSESPLEGTSH----------CHINLDETWTSKKKLFQVEIQPEEKHEEFRK 786
+ +K+ S S C + + W ++ V++ +E H+
Sbjct: 706 IKEMKEMYQSAEAKVSKSTGKWNCVEERICQLQRENPWLEQQ---LVDVHQKEDHK---- 758
Query: 787 VFELISLLNYTADQIRKKNRELEEE 811
E++ + + RKK+ LEE+
Sbjct: 759 --EIVINIQRGFIESRKKDLMLEEK 781
Score = 328 bits (841), Expect = 2e-89
Identities = 181/374 (48%), Positives = 261/374 (69%), Gaps = 8/374 (2%)
Query: 363 LRNDNQETAAMKPENLKKRKKRKKLKKRKEGAKAE---HNLKVASEEKQERLERSENKQP 419
L+ +N+E + N+ +K R++L+++++ K E L+ + + + + + N
Sbjct: 442 LKQENEEKTNV---NMLHKKNREELERKEKQYKKEVEAKQLEPTVQSLEMKPKTARNTPN 498
Query: 420 QDSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEK 479
QD ++ + KD M N +LK DIA+L++E+ +KND+L KE KY+++IK E NA EK
Sbjct: 499 QDFHNHEEVKDLMDENCILKTDIAILRQEICTMKNDNLEKENKYLKDIKIAKETNAALEK 558
Query: 480 SVRLNEEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHNKERLEAEVESLHSNLATAIN 539
++LNEEMITK Y Q+LNDLKAEN RLNS+L KEK +K++LEAE+ES S LA AI+
Sbjct: 559 CIKLNEEMITKTAFWYQQELNDLKAENTRLNSELLKEKESKKKLEAEIESYQSRLAAAIS 618
Query: 540 EYNE-ILERKDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKARVKFNTLKGKL 598
+++E + ++L+L L R D+S M S+IS++ DKN LTEQ+ K ++KFNTLK K
Sbjct: 619 KHSENVKTERNLKLALERTQDISEQVKMSSDISEIEDKNXFLTEQLSKMQIKFNTLKDKF 678
Query: 599 RETRDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAKESQSIGKQNSSEERIRQRE 658
R+TRD LR+K+LALE+VQ DL Q Q +IKEMK+M+ + EAK S+S GK N EERI Q +
Sbjct: 679 RKTRDTLRKKSLALETVQNDLSQTQQQIKEMKEMYQSAEAKVSKSTGKWNCVEERICQLQ 738
Query: 659 LENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDL-LEERNKELMNEYNYLKEKLLQ 717
EN LE+QL D ++ D+KEIVINI R +E+ K+DL LEE+NK+LMNEY++LKE L Q
Sbjct: 739 RENPWLEQQLVDVHQKEDHKEIVINIQRGFIESRKKDLMLEEKNKKLMNEYDHLKESLFQ 798
Query: 718 YEKEKAEREVIVRE 731
YE++KAE V ++E
Sbjct: 799 YERQKAETVVSIKE 812
>gi|239751523 PREDICTED: ankyrin repeat domain 20 family, member A5
[Homo sapiens]
Length = 823
Score = 358 bits (918), Expect = 3e-98
Identities = 271/805 (33%), Positives = 396/805 (49%), Gaps = 120/805 (14%)
Query: 102 KLLSFGRRLGQALLSSMDQEYAGRGYHIRDWELRKIHRAAIKGDAAEVEHCLTRRFRDLD 161
KL F R GQ +L S+D Y G GY IR EL+KIH+AA+KGDAAE+E CL RR DLD
Sbjct: 2 KLFGFRSRRGQTVLGSIDHLYTGSGYRIRYSELQKIHKAAVKGDAAEMERCLARRSGDLD 61
Query: 162 VRDKKDRTVLHLACAHGRVQVVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAIILLK 221
DK+ RT LHLACA G V+VVTLL++RKCQI+I D+ NRTPL++AVHCQEEACA+ILL+
Sbjct: 62 ALDKQHRTALHLACASGHVKVVTLLVNRKCQIDIYDKENRTPLIQAVHCQEEACAVILLE 121
Query: 222 RGANPNIKDIYGNTALHYAVYNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHM 281
GANPN+KDIYGNTALHYAVY+E TSLAE+LL H NIEAL+K+ NTPLLFAI +++ M
Sbjct: 122 HGANPNLKDIYGNTALHYAVYSESTSLAEKLLFHGENIEALDKDSNTPLLFAIICKKEKM 181
Query: 282 VEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIHISSQDMFGQTAEDYAFC 341
VEFLLKN+A+ HAVD + TAL+LAV ++ IV +LL+Q+I++ +QDM G+ AEDYA
Sbjct: 182 VEFLLKNKASTHAVDRLRXTALMLAVHYDSLGIVNILLKQSINVFTQDMCGRDAEDYAIS 241
Query: 342 CDLRSIQQQILEHKNKMLKN------------------------HLRNDNQETAAMK--- 374
C L IQQQILEHK +LKN +D + A K
Sbjct: 242 CRLTKIQQQILEHKKMILKNDKPDVGSSDESAVSIFHELCVDSLSALDDELLSVAAKQCV 301
Query: 375 PENLKK-------RKKRKKLKKRKEGAKAEH-NLKVASE--------------------- 405
PE + + K + + + EG A+H +LK ++E
Sbjct: 302 PEKVSEPLRGPSHGKGNRIVNGKGEGPPAKHPSLKPSTEMEDPAVKGAVQXKNVQTLRAE 361
Query: 406 --------EKQERLERSENKQPQDSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSL 457
E+Q+R ERSE KQPQ + K E L +I ++ D L
Sbjct: 362 QALPVASEEEQQRRERSEKKQPQVIEGNNTYKSE---KIQLSENIC---HSTFSAAADRL 415
Query: 458 RKEKKYIQEIKSITEINANFEKSVRLNEEMITKKVAQYSQQLNDLKAENARLNSKLE-KE 516
+++K + F K ++ + T K Q +++ ++ + + +LE KE
Sbjct: 416 TQQRKIGKTYPQ------QFPKKLKEEHDRCTLK--QENEEKTNVNMLHKKNREELERKE 467
Query: 517 KHNKERLEAE-----VESLHSNLATAIN-------EYNEILERKDLELVLWRADDVSRHE 564
K K+ +EA+ V+SL TA N + E+ + D +L + R E
Sbjct: 468 KQYKKEVEAKQLEPTVQSLEMKPKTARNTPNQDFHNHEEVKDLMDENCILKTDIAILRQE 527
Query: 565 TMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKTLALESVQL-DLKQAQ 623
L +N+ L + K + N K + + + KT +L DLK
Sbjct: 528 ICTMKNDNLEKENKYLKD--IKIAKETNAALEKCIKLNEEMITKTAFWYQQELNDLKAEN 585
Query: 624 HRIKEMKQMHPNGEAKESQSIGKQNSSEERIRQRELENLLLERQLEDARKEGDNKEIVIN 683
R+ + K I S + EN+ ER L+ A + + +
Sbjct: 586 TRLNSELLKEKESKKKLEAEIESYQSRLAAAISKHSENVKTERNLKLALERTQDISEQVK 645
Query: 684 IHRDCLE-NGKEDLLEERNKELMNEYNYLKEKLLQYEKEKAEREVIVREFQEEL------ 736
+ D E K L E+ ++ ++N LK+K + ++ + + Q +L
Sbjct: 646 MSSDISEIEDKNXFLTEQLSKMQIKFNTLKDKFRKTRDTLRKKSLALETVQNDLSQTQQQ 705
Query: 737 VDHLKKFSMSESPLEGTSH----------CHINLDETWTSKKKLFQVEIQPEEKHEEFRK 786
+ +K+ S S C + + W ++ V++ +E H+
Sbjct: 706 IKEMKEMYQSAEAKVSKSTGKWNCVEERICQLQRENPWLEQQ---LVDVHQKEDHK---- 758
Query: 787 VFELISLLNYTADQIRKKNRELEEE 811
E++ + + RKK+ LEE+
Sbjct: 759 --EIVINIQRGFIESRKKDLMLEEK 781
Score = 328 bits (841), Expect = 2e-89
Identities = 181/374 (48%), Positives = 261/374 (69%), Gaps = 8/374 (2%)
Query: 363 LRNDNQETAAMKPENLKKRKKRKKLKKRKEGAKAE---HNLKVASEEKQERLERSENKQP 419
L+ +N+E + N+ +K R++L+++++ K E L+ + + + + + N
Sbjct: 442 LKQENEEKTNV---NMLHKKNREELERKEKQYKKEVEAKQLEPTVQSLEMKPKTARNTPN 498
Query: 420 QDSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEK 479
QD ++ + KD M N +LK DIA+L++E+ +KND+L KE KY+++IK E NA EK
Sbjct: 499 QDFHNHEEVKDLMDENCILKTDIAILRQEICTMKNDNLEKENKYLKDIKIAKETNAALEK 558
Query: 480 SVRLNEEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHNKERLEAEVESLHSNLATAIN 539
++LNEEMITK Y Q+LNDLKAEN RLNS+L KEK +K++LEAE+ES S LA AI+
Sbjct: 559 CIKLNEEMITKTAFWYQQELNDLKAENTRLNSELLKEKESKKKLEAEIESYQSRLAAAIS 618
Query: 540 EYNE-ILERKDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKARVKFNTLKGKL 598
+++E + ++L+L L R D+S M S+IS++ DKN LTEQ+ K ++KFNTLK K
Sbjct: 619 KHSENVKTERNLKLALERTQDISEQVKMSSDISEIEDKNXFLTEQLSKMQIKFNTLKDKF 678
Query: 599 RETRDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAKESQSIGKQNSSEERIRQRE 658
R+TRD LR+K+LALE+VQ DL Q Q +IKEMK+M+ + EAK S+S GK N EERI Q +
Sbjct: 679 RKTRDTLRKKSLALETVQNDLSQTQQQIKEMKEMYQSAEAKVSKSTGKWNCVEERICQLQ 738
Query: 659 LENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDL-LEERNKELMNEYNYLKEKLLQ 717
EN LE+QL D ++ D+KEIVINI R +E+ K+DL LEE+NK+LMNEY++LKE L Q
Sbjct: 739 RENPWLEQQLVDVHQKEDHKEIVINIQRGFIESRKKDLMLEEKNKKLMNEYDHLKESLFQ 798
Query: 718 YEKEKAEREVIVRE 731
YE++KAE V ++E
Sbjct: 799 YERQKAETVVSIKE 812
>gi|239756999 PREDICTED: ankyrin repeat domain 62 [Homo sapiens]
Length = 917
Score = 285 bits (730), Expect = 2e-76
Identities = 249/933 (26%), Positives = 448/933 (48%), Gaps = 109/933 (11%)
Query: 122 YAGRGYHIRDWELRKIHRAAIKGDAAEVEHCLTRRFRDLDVRDKKDRTVLHLACAHGRVQ 181
++ GY +R +L IH+AAI GD +V + R DL+ RDKK+RT L LACAHGR
Sbjct: 27 FSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILLRLNDLNDRDKKNRTALLLACAHGRPG 86
Query: 182 VVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAIILLKRGANPNIKDIYGNTALHYAV 241
VV L+ RKCQ+N+ D NRT L+KAV CQEE CA ILL+ GANPN++D+YGNTALHYA+
Sbjct: 87 VVADLVARKCQLNLTDSENRTALIKAVQCQEEVCASILLEHGANPNVRDMYGNTALHYAI 146
Query: 242 YNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNFKRT 301
NE S+A +LL++ A+IEA +++G+T LL A+N +++ MV FLLK + ++ A+DNF RT
Sbjct: 147 DNENISMARKLLAYGADIEARSQDGHTSLLLAVNRKKEQMVSFLLKKKPDLTAIDNFGRT 206
Query: 302 ALILAVQHNLSSIVTLLLQQNIHISSQDMFGQTAEDYAFCCDLRSIQQQILEHKNKMLKN 361
ALILA ++ +S+V LLQ NI + QD+ G TAEDYA ++I+ I E+K +
Sbjct: 207 ALILAARNGSTSVVYQLLQHNIDVFCQDISGWTAEDYAVASKFQAIRGMISEYKANKRRK 266
Query: 362 HLRNDNQE-----TAAMKPENLK---------KRKKRKKLKKRKEGAKAEH--NLKVASE 405
L+N N E T+ + E L+ + K +K K+ E ++ H + ++
Sbjct: 267 SLQNSNSEQDLEMTSEGEQERLEGCESSQPQVEEKMKKCRNKKMEVSRNVHADDSDNYND 326
Query: 406 EKQERLERSENKQPQDSQSYGKKKDEMFGNFMLK--RDIAMLKEELYAIKNDSLRKEKKY 463
+ E + + +N++P + QS GK+ E F K + + +K ++Y +
Sbjct: 327 DVDELIHKIKNRKPDNHQSPGKENGE-FDRLARKTSNEKSKVKSQIYFTDD--------- 376
Query: 464 IQEIKSITEINANFEKSVRLNEEMITKKVAQYSQQLNDL------KAENARLNSKLEKEK 517
+ +I +E + ++ ++E + Q + D K A +E +K
Sbjct: 377 LNDISGSSEKTSEDDELPYSDDENFMLLIKQSGMECKDFVSLSKSKNATAACGRSIEDQK 436
Query: 518 HNKERLEAEVESLHSNLATAINEYNEILERKDLELVLWRADDVSRHETMGSN-------- 569
ERL+ + + + +N I+ ++L D + S H+ +
Sbjct: 437 CYCERLKVKFQKMKNN----ISVLQKVLSETD------KTKSQSEHQNLQGKKKLCNLRF 486
Query: 570 ISQLTDKNELLTEQVHKARV-KFNTLKGKLRETRDALREKTLALESVQLDLKQAQHRIKE 628
I Q ++ + E++++ + + ++ + R + ++ L L+S++++LK + +
Sbjct: 487 ILQQQEEERIKAEELYEKDIEELKIMEEQYRTQTEVKKQSKLTLKSLEVELKTVRSNSNQ 546
Query: 629 MKQMHPNGEAKESQSIGKQNSSEERIRQRELENLLLE-RQLEDARKEGDNK-----EIVI 682
H + + + ++N + + E+ L LE ++ +E +NK EI+
Sbjct: 547 NFHTH-----ERERDLWQEN----HLMRDEIARLRLEIDTIKHQNQETENKYFKDIEIIK 597
Query: 683 NIHRD---CLENGKEDL---LEERNKE---LMNEYNYLKEKLLQYEKEKAEREVIVREFQ 733
+ D L+ +E L + +KE LM+E L +L + ++ + E + ++
Sbjct: 598 ENNEDLEKTLKRNEETLTKTITRYSKELNVLMDENTMLNSELQKEKQSMSRLETEMESYR 657
Query: 734 ----EELVDHLKKFSMS---ESPLEGTSHCHINLDETWTSKKKLFQVEIQPEEKHEEFRK 786
L DH ++ S + + T + +L E S ++ ++ E
Sbjct: 658 CRLAAALCDHDQRQSSKRDLQLAFQSTVNEWCHLQEDTNSHIQILSQQLSKAESTSS--- 714
Query: 787 VFELISLLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLK 846
L + L+Y + +++K +E + ++ + + N+ + Q
Sbjct: 715 --GLETELHYEREALKEKTLHIEHMQGVLSRTQRRLEDIEHMYQNDQPILEKYVRKQQSV 772
Query: 847 MDILFKKLKQKFDDLMAEKEAVSSKCVNLAKDNEVLHQELLSMG-KVQEKCEKLEKDKKM 905
D LF+ L ++ +C + K + + ++++ K ++ EKL+ + +
Sbjct: 773 EDGLFQ--------LQSQNLLYQQQCNDARKKADNQEKTIINIQVKCEDTVEKLQAECRK 824
Query: 906 LEEKVLNLKTHMEKDMVELGKVQEYKSELDERAMQAIEKLEEIH--LQKQAEYEKQLE-- 961
LEE N K M++ + + +Y+ E +ER + + E+ L KQ E LE
Sbjct: 825 LEE---NNKGLMKECTLLKERQCQYEKEKEEREVVRRQLQREVDDALNKQLLLEAMLEIS 881
Query: 962 ---QLN-KDNTASLKKKELTLKDVECKFSKMKT 990
++N +D SLKKK ++ C M T
Sbjct: 882 SERRINLEDEAQSLKKKLGQMRSQVCMKLSMST 914
>gi|239751514 PREDICTED: ankyrin repeat domain 62 isoform 4 [Homo
sapiens]
Length = 917
Score = 285 bits (730), Expect = 2e-76
Identities = 249/933 (26%), Positives = 448/933 (48%), Gaps = 109/933 (11%)
Query: 122 YAGRGYHIRDWELRKIHRAAIKGDAAEVEHCLTRRFRDLDVRDKKDRTVLHLACAHGRVQ 181
++ GY +R +L IH+AAI GD +V + R DL+ RDKK+RT L LACAHGR
Sbjct: 27 FSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILLRLNDLNDRDKKNRTALLLACAHGRPG 86
Query: 182 VVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAIILLKRGANPNIKDIYGNTALHYAV 241
VV L+ RKCQ+N+ D NRT L+KAV CQEE CA ILL+ GANPN++D+YGNTALHYA+
Sbjct: 87 VVADLVARKCQLNLTDSENRTALIKAVQCQEEVCASILLEHGANPNVRDMYGNTALHYAI 146
Query: 242 YNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNFKRT 301
NE S+A +LL++ A+IEA +++G+T LL A+N +++ MV FLLK + ++ A+DNF RT
Sbjct: 147 DNENISMARKLLAYGADIEARSQDGHTSLLLAVNRKKEQMVSFLLKKKPDLTAIDNFGRT 206
Query: 302 ALILAVQHNLSSIVTLLLQQNIHISSQDMFGQTAEDYAFCCDLRSIQQQILEHKNKMLKN 361
ALILA ++ +S+V LLQ NI + QD+ G TAEDYA ++I+ I E+K +
Sbjct: 207 ALILAARNGSTSVVYQLLQHNIDVFCQDISGWTAEDYAVASKFQAIRGMISEYKANKRRK 266
Query: 362 HLRNDNQE-----TAAMKPENLK---------KRKKRKKLKKRKEGAKAEH--NLKVASE 405
L+N N E T+ + E L+ + K +K K+ E ++ H + ++
Sbjct: 267 SLQNSNSEQDLEMTSEGEQERLEGCESSQPQVEEKMKKCRNKKMEVSRNVHADDSDNYND 326
Query: 406 EKQERLERSENKQPQDSQSYGKKKDEMFGNFMLK--RDIAMLKEELYAIKNDSLRKEKKY 463
+ E + + +N++P + QS GK+ E F K + + +K ++Y +
Sbjct: 327 DVDELIHKIKNRKPDNHQSPGKENGE-FDRLARKTSNEKSKVKSQIYFTDD--------- 376
Query: 464 IQEIKSITEINANFEKSVRLNEEMITKKVAQYSQQLNDL------KAENARLNSKLEKEK 517
+ +I +E + ++ ++E + Q + D K A +E +K
Sbjct: 377 LNDISGSSEKTSEDDELPYSDDENFMLLIKQSGMECKDFVSLSKSKNATAACGRSIEDQK 436
Query: 518 HNKERLEAEVESLHSNLATAINEYNEILERKDLELVLWRADDVSRHETMGSN-------- 569
ERL+ + + + +N I+ ++L D + S H+ +
Sbjct: 437 CYCERLKVKFQKMKNN----ISVLQKVLSETD------KTKSQSEHQNLQGKKKLCNLRF 486
Query: 570 ISQLTDKNELLTEQVHKARV-KFNTLKGKLRETRDALREKTLALESVQLDLKQAQHRIKE 628
I Q ++ + E++++ + + ++ + R + ++ L L+S++++LK + +
Sbjct: 487 ILQQQEEERIKAEELYEKDIEELKIMEEQYRTQTEVKKQSKLTLKSLEVELKTVRSNSNQ 546
Query: 629 MKQMHPNGEAKESQSIGKQNSSEERIRQRELENLLLE-RQLEDARKEGDNK-----EIVI 682
H + + + ++N + + E+ L LE ++ +E +NK EI+
Sbjct: 547 NFHTH-----ERERDLWQEN----HLMRDEIARLRLEIDTIKHQNQETENKYFKDIEIIK 597
Query: 683 NIHRD---CLENGKEDL---LEERNKE---LMNEYNYLKEKLLQYEKEKAEREVIVREFQ 733
+ D L+ +E L + +KE LM+E L +L + ++ + E + ++
Sbjct: 598 ENNEDLEKTLKRNEETLTKTITRYSKELNVLMDENTMLNSELQKEKQSMSRLETEMESYR 657
Query: 734 ----EELVDHLKKFSMS---ESPLEGTSHCHINLDETWTSKKKLFQVEIQPEEKHEEFRK 786
L DH ++ S + + T + +L E S ++ ++ E
Sbjct: 658 CRLAAALCDHDQRQSSKRDLQLAFQSTVNEWCHLQEDTNSHIQILSQQLSKAESTSS--- 714
Query: 787 VFELISLLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLK 846
L + L+Y + +++K +E + ++ + + N+ + Q
Sbjct: 715 --GLETELHYEREALKEKTLHIEHMQGVLSRTQRRLEDIEHMYQNDQPILEKYVRKQQSV 772
Query: 847 MDILFKKLKQKFDDLMAEKEAVSSKCVNLAKDNEVLHQELLSMG-KVQEKCEKLEKDKKM 905
D LF+ L ++ +C + K + + ++++ K ++ EKL+ + +
Sbjct: 773 EDGLFQ--------LQSQNLLYQQQCNDARKKADNQEKTIINIQVKCEDTVEKLQAECRK 824
Query: 906 LEEKVLNLKTHMEKDMVELGKVQEYKSELDERAMQAIEKLEEIH--LQKQAEYEKQLE-- 961
LEE N K M++ + + +Y+ E +ER + + E+ L KQ E LE
Sbjct: 825 LEE---NNKGLMKECTLLKERQCQYEKEKEEREVVRRQLQREVDDALNKQLLLEAMLEIS 881
Query: 962 ---QLN-KDNTASLKKKELTLKDVECKFSKMKT 990
++N +D SLKKK ++ C M T
Sbjct: 882 SERRINLEDEAQSLKKKLGQMRSQVCMKLSMST 914
>gi|239746016 PREDICTED: ankyrin repeat domain 62 isoform 1 [Homo
sapiens]
Length = 917
Score = 283 bits (724), Expect = 8e-76
Identities = 257/920 (27%), Positives = 436/920 (47%), Gaps = 126/920 (13%)
Query: 122 YAGRGYHIRDWELRKIHRAAIKGDAAEVEHCLTRRFRDLDVRDKKDRTVLHLACAHGRVQ 181
++ GY +R +L IH+AAI GD +V + R DL+ RDKK+RT L LACAHGR
Sbjct: 27 FSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILLRLNDLNDRDKKNRTALLLACAHGRPG 86
Query: 182 VVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAIILLKRGANPNIKDIYGNTALHYAV 241
VV L+ RKCQ+N+ D NRT L+KAV CQEE CA ILL+ GANPN++D+YGNTALHYA+
Sbjct: 87 VVADLVARKCQLNLTDSENRTALIKAVQCQEEVCASILLEHGANPNVRDMYGNTALHYAI 146
Query: 242 YNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNFKRT 301
NE S+A +LL++ A+IEA +++G+T LL A+N +++ MV FLLK + ++ A+DNF RT
Sbjct: 147 DNENISMARKLLAYGADIEARSQDGHTSLLLAVNRKKEQMVAFLLKKKPDLTAIDNFGRT 206
Query: 302 ALILAVQHNLSSIVTLLLQQNIHISSQDMFGQTAEDYAFCCDLRSIQQQILEHKNKMLKN 361
ALILA ++ +S+V LLQ NI + QD+ G TAEDYA ++I+ I E+K
Sbjct: 207 ALILAARNGSTSVVYQLLQHNIDVFCQDISGWTAEDYAVASKFQAIRGMISEYKANKRCK 266
Query: 362 HLRNDNQE-----TAAMKPENLK---------KRKKRKKLKKRKEGAKAEH--NLKVASE 405
L+N N E T+ + E L+ + K +K K+ E ++ H + ++
Sbjct: 267 SLQNSNSEQDLEMTSEGEQERLEGCESSQPQVEEKMKKCRNKKMEVSRNVHADDSDNYND 326
Query: 406 EKQERLERSENKQPQDSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSLRKEKKYIQ 465
+ E + + +N++P + QS GK+ E + L ++ K K I
Sbjct: 327 DVDELIHKIKNRKPDNHQSPGKENGEF--------------DRLARKTSNEKSKVKSQIY 372
Query: 466 EIKSITEINANFEKSVRLNE------EMITKKVAQYSQQLNDL------KAENARLNSKL 513
+ +I+ + EK+ +E E + Q + D K A +
Sbjct: 373 FTDDLNDISGSSEKTSEDDELPYSDDENFMLLIEQSGMECKDFVSLSKSKNATAACGRSI 432
Query: 514 EKEKHNKERLEAEVESLHSNLATAINEYNEILERKDLELVLWRADDVSRHETMGSNISQL 573
E +K ERL+ + + + +N++ ++L D + S H+ + +L
Sbjct: 433 EDQKCYCERLKVKFQKMKNNISVL----QKVLSETD------KTKSQSEHQNLQGK-KKL 481
Query: 574 TDKNELLTEQVHKARVKFNTLKGKLRETRDALREKTLALESVQLDLKQAQHRIKEMKQMH 633
+ +L +Q + R+K L K E + E+ V+ KQ++ +K ++
Sbjct: 482 CNLRFILQQQ-EEERIKAEELYEKDIEELKIMEEQYRTQTEVK---KQSKLTLKSLEV-- 535
Query: 634 PNGEAKESQSIGKQN-SSEERIRQRELENLLLERQLEDARKEGD-----NKEIVINIHRD 687
E K +S QN + ER R EN L+ ++ R E D N+E +D
Sbjct: 536 ---ELKTVRSNSNQNFHTHERERDLWQENHLMRDEIARLRLEIDTIKHQNQETENKYFKD 592
Query: 688 CLENGKEDLLEERNKELMNEYNYLKEKLLQYEKEKAEREVIVREFQEELVDHLKKFSMSE 747
++++E N++L EK L+ E+A + I R + +EL + + +M
Sbjct: 593 I------EIIKENNEDL--------EKTLK-RNEEALTKTITR-YSKELNVLMDENTMLN 636
Query: 748 SPLEGTSHCHINLDETWTSKKKLFQVEIQPEEKHEEFRKVFELISLLNYTADQIRKKNRE 807
S L+ K+K ++ E + R +L ++ Q K++ +
Sbjct: 637 SELQ---------------KEKQSMSRLETEMESYRCRLA---AALCDHDQRQSSKRDLQ 678
Query: 808 LEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQL-KMDILFKKLKQKFDDLMAEKE 866
L ++T + C ED + H + + QL K + L+ +L E+E
Sbjct: 679 LAFQSTVNEWC----------HLQEDTNSHIQILSQQLSKAESTSSGLET---ELHYERE 725
Query: 867 AVSSKCVNLAKDNEVLHQELLSMGKVQEKCEKLEKDKKMLEEKVLNLKTHMEKDMVELGK 926
A+ K +++ VL + + E E + ++ + + EK + + +E + +L
Sbjct: 726 ALKEKTLHIEHMQGVLSRTQRRL----EDIEHMYQNDQPILEKYVRKQQSVEDGLFQLQS 781
Query: 927 VQEYKSELDERAMQAIEKLEEIHLQKQAEYEKQLEQLN------KDNTASLKKKELTLKD 980
+ A + + E+ + Q + E +E+L ++N L K+ LK+
Sbjct: 782 QNLLYQQQCNDARKKADNQEKTIINIQVKCEDTVEKLQAECRKLEENNKGLMKECTLLKE 841
Query: 981 VECKFSKMKTAYEDVTTELE 1000
+C++ K K E V +L+
Sbjct: 842 RQCQYEKEKEEREVVRRQLQ 861
>gi|53828703 POTE ankyrin domain family, member A isoform 2 [Homo
sapiens]
Length = 498
Score = 252 bits (644), Expect = 1e-66
Identities = 140/301 (46%), Positives = 193/301 (64%), Gaps = 29/301 (9%)
Query: 119 DQEYAGRGYHIRDWELRKIHRAAIKGDAAEVEHCLTRRFRDLDVRDKKDRTVLHLACAHG 178
D + YH+R +L K+HRAA G+ + + R ++ RDKK RT LHLACA+G
Sbjct: 51 DSAFTEPRYHVRREDLGKLHRAAWWGEVPRADLIVMLRGPGINKRDKKKRTALHLACANG 110
Query: 179 RVQVVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAIILLKRGANPNIKDIYGNTALH 238
+VV+LLLDR+CQ+++ D RT L+KAV CQE+ CA++LL+ G +PN+ D+YGNTALH
Sbjct: 111 NSEVVSLLLDRQCQLHVFDSKKRTALIKAVQCQEDECALMLLQHGTDPNLPDMYGNTALH 170
Query: 239 YAVYNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNF 298
YAVYNE +A+ LL + A+IE+ NK G TPLL A++ ++Q MV+FL+K +AN++A+D F
Sbjct: 171 YAVYNEDKLMAKTLLLYGADIESKNKGGLTPLLLAVHGQKQRMVKFLIKKKANLNALDRF 230
Query: 299 KRTALILAVQHNLSSIVTLLLQQNIHISSQDMFGQTAEDYAFCCDLRSIQQQILEHK-NK 357
RTALILAV+ +SIV+LLLQQNI + SQD+FGQTAEDYA I Q + ++K N+
Sbjct: 231 GRTALILAVRCGSASIVSLLLQQNIDVFSQDVFGQTAEDYAVSSHHSIICQLLSDYKENQ 290
Query: 358 MLKNHLRNDNQETAAMKPENLKKRKKRKKLKKRKEGAKAEHNLKVASEEKQERLERSENK 417
M N N N E +LK+ SEE+ +RL+ SEN
Sbjct: 291 MPNNSSGNSN----------------------------PEQDLKLTSEEEPQRLKGSENS 322
Query: 418 Q 418
Q
Sbjct: 323 Q 323
>gi|149363642 coiled-coil domain containing 144A [Homo sapiens]
Length = 1427
Score = 251 bits (642), Expect = 3e-66
Identities = 234/871 (26%), Positives = 405/871 (46%), Gaps = 162/871 (18%)
Query: 237 LHYAVYNEGTSLAERLLSHHANIEALNKEGNT----PLLFAINSRRQHMVEFLLKNQANI 292
L ++VY L E+L + + +L + +T L + + + LK N+
Sbjct: 610 LSHSVYENFMLLIEQLRMEYKDSASLPRIQDTFCLCEHLLKLKNNHCDQLTVKLKQMENM 669
Query: 293 HAV-----DNFKRTALILAVQH-----NLSSIVTLLLQQNIHISSQDM-FGQTAEDYAF- 340
+V K+T L L +Q L + L Q+N + DM + + +E
Sbjct: 670 VSVLQNELSETKKTKLQLELQKIEWEKELYDLRLALKQENEEKRNADMLYNKDSEQLRIK 729
Query: 341 ---CCDLRSIQQQILEHKNKMLKNHLRNDNQETAAMKPENLKKRKKRKKLKKRKEGAKAE 397
C + +QQ+ + +++K N ++ N +K+L + ++ +
Sbjct: 730 EEECGKVVETKQQLKWNLRRLVKELRTVRNNLDLVVQERN----DAQKQLSEEQDARILQ 785
Query: 398 HNLKVASEEKQERLERSENKQPQD-SQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDS 456
+ + KQ+ LE + K + S + K+KD + ML+ +IA+L+ E+ IKN +
Sbjct: 786 DQILTS---KQKELEMARKKMNSEISHRHQKEKDLFHEDCMLQEEIALLRLEIDTIKNQN 842
Query: 457 LRKEKKYIQEIKSITEINANFEKSVRLNEEMITKKVAQYSQQLNDLKAENARLNSKLEKE 516
+KEKKY ++I+++ E N N +K ++LNEE +T+ + QYS QLN+L AEN LNS+LE
Sbjct: 843 KQKEKKYFEDIEAVKEKNDNLQKIIKLNEETLTETILQYSGQLNNLTAENKILNSELENG 902
Query: 517 KHNKERLEAEVESLHSNLATAINEYNEILERKDLELVLWRA--DDVSRHETMGSNISQLT 574
K N+ERLE E+ES LA A+ + ++ +DL+L R + V H+ M ++S L
Sbjct: 903 KQNQERLEIEMESYRCRLAAAVRDCDQSQTARDLKLDFQRTRQEWVRLHDKMKVDMSGLQ 962
Query: 575 DKNELLTEQVHKARVKFNTLKGKLRETRDALREKTLALESVQLDLKQAQHRIKEMKQMHP 634
KNE+L+E++ A K N+L+ +L TRDAL ++L LE VQ DL Q Q + KE +QM+
Sbjct: 963 AKNEILSEKLSNAESKINSLQIQLHNTRDALGRESLILERVQRDLSQTQCQKKETEQMYQ 1022
Query: 635 NGEAKESQSIGKQNSSEERIRQRELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKE 694
++K + I KQ S EER+ Q + EN+LL +QL+DA K+ +++E + +D + +
Sbjct: 1023 IEQSKLKKYIAKQESVEERLSQLQSENMLLRQQLDDAHKKANSQEKTSSTIQDQFHSAAK 1082
Query: 695 DL----------LEERNKELMNEYNYLKEKLLQYEKEKAEREVIVREFQEELVDHLKKFS 744
+L L+E+NKELM+EYN+LKE++ Q EKEKA R++ + E QE +
Sbjct: 1083 NLQAESEKQILSLQEKNKELMDEYNHLKERMDQCEKEKAGRKIDLTEAQETV-------- 1134
Query: 745 MSESPLEGTSHCHINLDETWTSKKKLFQVEIQPEEKHEEFRKVFELISLLNYTADQIRKK 804
S C + + E + + ++ + + + ++K
Sbjct: 1135 --------PSRC----------------LHLDAENEVLQLQQTLFSMKAIQKQCETLQKN 1170
Query: 805 NRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFDDLMAE 864
++L++E K +E NML E H L ++ + +I
Sbjct: 1171 KKQLKQEVVNLKSYMER--NMLERGKAE---WHKLLIEERARKEI--------------- 1210
Query: 865 KEAVSSKCVNLAKDNEVLHQELLSMGKVQEKCEKLEKDKKMLEEKVLNLKTHMEKDMVEL 924
+E ++ + L K V H++L+ ++ E+ ++KT ME
Sbjct: 1211 EEKLNEAILTLQKQAAVSHEQLV----------------QLREDNTTSIKTQMEL----- 1249
Query: 925 GKVQEYKSELDERAMQAIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVECK 984
+++ +SE+ QA++ K T + KEL L++V+ +
Sbjct: 1250 -TIKDLESEISRIK------------TSQADFNK---------TELERYKELYLEEVKVR 1287
Query: 985 FSKMKTAYEDVTTELEEYKEAFAVALKANSSMSEKITKSDKKIAVISTKLFMEKERMEYF 1044
E ++ EL E A + ++ ++ T+S +T+
Sbjct: 1288 --------ESLSNELSRTNEMIA-EVSTQLTVEKEQTRSRSLFTAYATR----------- 1327
Query: 1045 LSTLPMRPDPELPCVENLNSIE-LNRKYIPK 1074
P E PCV NLN E LNRK+IP+
Sbjct: 1328 -------PVLESPCVGNLNDSEGLNRKHIPR 1351
Score = 65.5 bits (158), Expect = 3e-10
Identities = 133/701 (18%), Positives = 290/701 (41%), Gaps = 109/701 (15%)
Query: 439 KRDIAMLKEELYAIKNDSLRKEKKYIQEIK----SITEINANFEKSVR-------LNEEM 487
K ++ L+EE A+K + ++ K +E++ + TE++ LN+++
Sbjct: 503 KNEVNTLEEEFLALKKEDVQLHKDVEEEMEKHRSNSTELSGTLTDGTTVGNDDDGLNQQI 562
Query: 488 ITKKVAQYSQQLNDLKAENARLNSKLEKEKHNKERLE-AEVESLHSNLATAINEYNEILE 546
K+ ++ + + E + +++ E + +E +E+ S L+ ++ E N +L
Sbjct: 563 PRKENGEHDRPADKTSNEKNEVKNQIYPEADFADSMEPSEIASEDCELSHSVYE-NFMLL 621
Query: 547 RKDLELVLWRADDVSRHE---TMGSNISQLTDKN-ELLTEQVHKARVKFNTLKGKLRETR 602
+ L + + + R + + ++ +L + + + LT ++ + + L+ +L ET
Sbjct: 622 IEQLRMEYKDSASLPRIQDTFCLCEHLLKLKNNHCDQLTVKLKQMENMVSVLQNELSET- 680
Query: 603 DALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAKESQSIGKQNSSEERIRQRELENL 662
++ L LE +++ ++ + ++ + N E + + + ++S + RI++ E +
Sbjct: 681 ---KKTKLQLELQKIEWEKELYDLR-LALKQENEEKRNADMLYNKDSEQLRIKEEECGKV 736
Query: 663 L---------LERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKELMNEYNYL-K 712
+ L R +++ R +N ++V+ D ++ L EE++ ++ + K
Sbjct: 737 VETKQQLKWNLRRLVKELRTVRNNLDLVVQERND----AQKQLSEEQDARILQDQILTSK 792
Query: 713 EKLLQYEKEKAEREVIVREFQEELVDHLKKFSMSESPLEGTSHCHINLDETWTSKKKLFQ 772
+K L+ ++K E+ R +E+ + H E L I ++ +KK F+
Sbjct: 793 QKELEMARKKMNSEISHRHQKEKDLFHEDCMLQEEIALLRLEIDTIK-NQNKQKEKKYFE 851
Query: 773 VEIQPEEKHEEFRKVFEL------ISLLNYTA--DQIRKKNRELEEEATGYKKCLE-MTI 823
+EK++ +K+ +L ++L Y+ + + +N+ L E K+ E + I
Sbjct: 852 DIEAVKEKNDNLQKIIKLNEETLTETILQYSGQLNNLTAENKILNSELENGKQNQERLEI 911
Query: 824 NMLN---AFANEDFSCHGDLNTDQLKMDI---------LFKKLKQKFDDLMAEKEAVSSK 871
M + A C LK+D L K+K L A+ E +S K
Sbjct: 912 EMESYRCRLAAAVRDCDQSQTARDLKLDFQRTRQEWVRLHDKMKVDMSGLQAKNEILSEK 971
Query: 872 CVN-----------LAKDNEVLHQELLSMGKVQEKCEKLEKDKKMLEEKVLNLKTHMEKD 920
N L + L +E L + +VQ + + KK E+ ++ ++K
Sbjct: 972 LSNAESKINSLQIQLHNTRDALGRESLILERVQRDLSQTQCQKKETEQMYQIEQSKLKKY 1031
Query: 921 MVELGKVQEYKSELDERAMQAIEKLEEIHLQK---------------------QAEYEKQ 959
+ + V+E S+L M ++L++ H + QAE EKQ
Sbjct: 1032 IAKQESVEERLSQLQSENMLLRQQLDDAHKKANSQEKTSSTIQDQFHSAAKNLQAESEKQ 1091
Query: 960 LEQLNKDNTASLKKKELTLKDVECKFSKMKTAYEDVTTELEE----------------YK 1003
+ L + N L + LK+ + K K + TE +E
Sbjct: 1092 ILSLQEKN-KELMDEYNHLKERMDQCEKEKAGRKIDLTEAQETVPSRCLHLDAENEVLQL 1150
Query: 1004 EAFAVALKANSSMSEKITKSDKKI--AVISTKLFMEKERME 1042
+ ++KA E + K+ K++ V++ K +ME+ +E
Sbjct: 1151 QQTLFSMKAIQKQCETLQKNKKQLKQEVVNLKSYMERNMLE 1191
Score = 48.9 bits (115), Expect = 3e-05
Identities = 126/663 (19%), Positives = 247/663 (37%), Gaps = 117/663 (17%)
Query: 384 RKKLKKRKEGAKAEHNLKVASEEKQERLERSENKQPQDSQS------------------- 424
+ +L + KE +AE + ++ SEE+QERL+ ENKQPQ +
Sbjct: 210 QSQLPENKESKEAEQDSELTSEEEQERLKGCENKQPQKTSQEPEMAKDCDREDIPIYPVL 269
Query: 425 -YGKKKDEM-----------------------FGNFMLKRDIAMLKEELYAIKNDSLRKE 460
+ +K +EM FG K I EE + N + +
Sbjct: 270 PHVQKSEEMWIEQGKLEWKNQLKLVINELKQRFGEIYEKYKIPACPEEEPLLDNSTRGTD 329
Query: 461 KKYI------------QEIKSITEINANFEKSVRLNEEMITKKVAQYSQQLNDLKAENAR 508
K I +E S ++ FE E + + Y + + +
Sbjct: 330 VKDIPFNLTNNIPGCEEEDASEISVSVVFETFPEQKEPSLKNIIHPYYHPYSGSQEHVCQ 389
Query: 509 LNSKLEKEKHNKERLEAEVESLHSNLATAINEYNEILERK--DLELVLWR-ADDVSRHET 565
+SK ++ + + +T N +N+ +K + E+V+ +D
Sbjct: 390 SSSKFHLHENKLDCDNDNKPGIGHIFSTDKNFHNDASTKKARNPEVVMVEMKEDQEFDLQ 449
Query: 566 MGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKTLALESVQLDLKQAQHR 625
M N++Q +D T + K L L D E L E +Q D+++ ++
Sbjct: 450 MTKNMNQNSDSGS--TNNYKSLKPKLENL-SSLPPDSDRTSEVYLH-EELQQDMQKFKNE 505
Query: 626 IKEMKQMHPNGEAKESQSIGKQNSSEERIRQRELENLLLERQLEDARKEGDNKEIVINIH 685
+ +++ A + + + EE + + + L L D G N + +N
Sbjct: 506 VNTLEE---EFLALKKEDVQLHKDVEEEMEKHRSNSTELSGTLTDGTTVG-NDDDGLNQQ 561
Query: 686 RDCLENGKEDLLEERNKELMNEYNYLKEKLLQYEKEKAEREVIVREFQEELVDHLKKFSM 745
ENG+ D ++ NE N +K ++ + + D ++ +
Sbjct: 562 IPRKENGEHDRPADKTS---NEKNEVKNQIYP---------------EADFADSMEPSEI 603
Query: 746 SESPLEGTSHCHINLDETWTSKKKLFQVEIQPEEKHEEFRKVFELISLLNYTADQIRKKN 805
+ E + + N + ++ + F L+ L N DQ+ K
Sbjct: 604 ASEDCELSHSVYENFMLLIEQLRMEYKDSASLPRIQDTFCLCEHLLKLKNNHCDQLTVKL 663
Query: 806 RELEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKL---KQKFD--- 859
+++E NM++ NE T + K+ + +K+ K+ +D
Sbjct: 664 KQME--------------NMVSVLQNE------LSETKKTKLQLELQKIEWEKELYDLRL 703
Query: 860 DLMAEKEAVSSKCVNLAKDNEVLHQELLSMGKVQEKCEKLEKDKKMLEEKVLNLKTHMEK 919
L E E + + KD+E L + GKV E ++L+ + + L +++ ++ +++
Sbjct: 704 ALKQENEEKRNADMLYNKDSEQLRIKEEECGKVVETKQQLKWNLRRLVKELRTVRNNLDL 763
Query: 920 DMVELGKVQEYKS-ELDERAMQAIEKLEEIHLQKQAEYEKQLEQLNKD-NTASLKKKELT 977
+ E Q+ S E D R +Q ++I KQ E E +++N + + K+K+L
Sbjct: 764 VVQERNDAQKQLSEEQDARILQ-----DQILTSKQKELEMARKKMNSEISHRHQKEKDLF 818
Query: 978 LKD 980
+D
Sbjct: 819 HED 821
Score = 31.6 bits (70), Expect = 5.4
Identities = 16/40 (40%), Positives = 23/40 (57%)
Query: 127 YHIRDWELRKIHRAAIKGDAAEVEHCLTRRFRDLDVRDKK 166
+ +R +L ++HRAA GD VEH L +D RD+K
Sbjct: 74 HDVRLEDLGELHRAARSGDVPGVEHILAPGDTGVDKRDRK 113
>gi|239745058 PREDICTED: hypothetical protein XP_002343353 [Homo
sapiens]
Length = 544
Score = 249 bits (635), Expect = 2e-65
Identities = 170/507 (33%), Positives = 271/507 (53%), Gaps = 66/507 (13%)
Query: 119 DQEYAGRGYHIRDWELRKIHRAAIKGDAAEVEHCLTRRFRDLDVRDKKDRTVLHLACAHG 178
D + YH+R +L K+HRAA G + + R D++ RDK+ RT LHLA A+G
Sbjct: 88 DSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQKRTALHLASANG 147
Query: 179 RVQVVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAIILLKRGANPNIKDIYGNTALH 238
+VV LLLDR+CQ+N+ D RT L+KAV CQE+ C ++LL+ GA+ NI+D YGNTALH
Sbjct: 148 NSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADGNIQDEYGNTALH 207
Query: 239 YAVYNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNF 298
YA+YNE +A+ LL + A+IE+ NK G TPLL ++ ++Q +V+FL+K +AN++A+D +
Sbjct: 208 YAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQEVVKFLIKKKANLNALDRY 267
Query: 299 KRTALILAVQHNLSSIVTLLLQQNIHISSQDMFGQTAEDYAFCCDLRSIQQQILEHKNKM 358
RTALILAV +SIV LLL+QN+ +SSQD+ GQTA +YA I + + ++K K
Sbjct: 268 GRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDYKEKQ 327
Query: 359 LKNHLRNDNQETAAMKPENLKKRKKRKKLKKRKEGAKAEHNLKVASEEKQERLERSENKQ 418
+ LK E + E +LK+ SEE+ +RL+ SEN Q
Sbjct: 328 M---------------------------LKISSENSNPEQDLKLTSEEESQRLKVSENSQ 360
Query: 419 PQDSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFE 478
P+ K E N R++ +EE+ KK+ + E N
Sbjct: 361 PE------KMSQEPEINKDCDREV---EEEI-----------KKHGSNPVGLPENLTNGA 400
Query: 479 KSVRLNEEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHNKERLEAEVESLHSNLATAI 538
+ ++ +I ++ ++ K EN + +E H+ E+ + + + L T I
Sbjct: 401 SAGNGDDGLIPQRKSR--------KPENQQFPDTENEEYHSDEQNDTQ-KQLSEEQNTGI 451
Query: 539 NEYNEILERKDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKARVKFNTLK--- 595
++ +EIL K ++ + + S L +N +L E++ K R++ + K
Sbjct: 452 SQ-DEILTNKQKQIEVAEKEMNSELSLSHKKEEDLLRENSMLREEIAKLRLELDETKHQN 510
Query: 596 ----GKLRETRDALREKTLALESVQLD 618
K+ E ++++EK L+++QL+
Sbjct: 511 QLRENKILEEIESVKEK--LLKTIQLN 535
Score = 30.8 bits (68), Expect = 9.3
Identities = 34/153 (22%), Positives = 69/153 (45%), Gaps = 16/153 (10%)
Query: 925 GKVQEYKSELDERAMQAIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVECK 984
G + + KS E + EE H +Q + +KQL + + NT + + LT K
Sbjct: 408 GLIPQRKSRKPENQQFPDTENEEYHSDEQNDTQKQLSE--EQNTGISQDEILTNKQ---- 461
Query: 985 FSKMKTAYEDVTTELEEYKEAFAVALKANSSMSEKITKSDKKIAVISTKLFMEKERMEYF 1044
+++ A +++ +EL + L+ NS + E+I K +L +++ + +
Sbjct: 462 -KQIEVAEKEMNSELSLSHKKEEDLLRENSMLREEIAK---------LRLELDETKHQNQ 511
Query: 1045 LSTLPMRPDPELPCVENLNSIELNRKYIPKMAI 1077
L + + E + L +I+LN + + K +I
Sbjct: 512 LRENKILEEIESVKEKLLKTIQLNEEALTKTSI 544
>gi|52856430 protein expressed in prostate, ovary, testis, and
placenta 15 [Homo sapiens]
Length = 581
Score = 247 bits (631), Expect = 5e-65
Identities = 169/507 (33%), Positives = 271/507 (53%), Gaps = 66/507 (13%)
Query: 119 DQEYAGRGYHIRDWELRKIHRAAIKGDAAEVEHCLTRRFRDLDVRDKKDRTVLHLACAHG 178
D + YH+R +L K+HRAA G + + R D++ RDK+ RT LHLA A+G
Sbjct: 125 DSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQKRTALHLASANG 184
Query: 179 RVQVVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAIILLKRGANPNIKDIYGNTALH 238
+VV LLLDR+CQ+N+ D RT L+KAV CQE+ C ++LL+ GA+ NI+D YGNTALH
Sbjct: 185 NSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADGNIQDEYGNTALH 244
Query: 239 YAVYNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNF 298
YA+YNE +A+ LL + A+IE+ NK G TPLL ++ ++Q +V+FL+K +AN++A+D +
Sbjct: 245 YAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRY 304
Query: 299 KRTALILAVQHNLSSIVTLLLQQNIHISSQDMFGQTAEDYAFCCDLRSIQQQILEHKNKM 358
RTALILAV +SIV LLL+QN+ +SSQD+ GQTA +YA I + + ++K K
Sbjct: 305 GRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDYKEKQ 364
Query: 359 LKNHLRNDNQETAAMKPENLKKRKKRKKLKKRKEGAKAEHNLKVASEEKQERLERSENKQ 418
+ LK E + E +LK+ SEE+ +RL+ SEN Q
Sbjct: 365 M---------------------------LKISSENSNPEQDLKLTSEEESQRLKVSENSQ 397
Query: 419 PQDSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFE 478
P+ K E N R++ +EE+ KK+ + E N
Sbjct: 398 PE------KMSQEPEINKDCDREV---EEEI-----------KKHGSNPVGLPENLTNGA 437
Query: 479 KSVRLNEEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHNKERLEAEVESLHSNLATAI 538
+ ++ +I ++ ++ K EN + +E H+ E+ + + + L T I
Sbjct: 438 SAGNGDDGLIPQRKSR--------KPENQQFPDTENEEYHSDEQNDTQ-KQLSEEQNTGI 488
Query: 539 NEYNEILERKDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKARVKFNTLK--- 595
++ +EIL K ++ + + S+ L +N +L E++ R++ + K
Sbjct: 489 SQ-DEILTNKQKQIEVAEKEMNSKLSLSHKKEEDLLRENSMLREEIAMLRLELDETKHQN 547
Query: 596 ----GKLRETRDALREKTLALESVQLD 618
K+ E ++++EK L+++QL+
Sbjct: 548 QLRENKILEEIESVKEK--LLKAIQLN 572
>gi|209977003 ANKRD26-like family C, member 3 [Homo sapiens]
Length = 545
Score = 244 bits (624), Expect = 3e-64
Identities = 133/303 (43%), Positives = 189/303 (62%), Gaps = 27/303 (8%)
Query: 119 DQEYAGRGYHIRDWELRKIHRAAIKGDAAEVEHCLTRRFRDLDVRDKKDRTVLHLACAHG 178
D + YH+R +L K+HRAA G + + + D++ +DK+ RT LHLA A+G
Sbjct: 162 DSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLKDTDMNKKDKQKRTALHLASANG 221
Query: 179 RVQVVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAIILLKRGANPNIKDIYGNTALH 238
+VV LLLDR+CQ+NI D RT L KAV CQE+ CA++LL+ G +PNI D YGNTALH
Sbjct: 222 NSEVVKLLLDRRCQLNILDNKKRTALTKAVQCQEDECALMLLEHGTDPNIPDEYGNTALH 281
Query: 239 YAVYNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNF 298
YA+YNE +A+ LL + A+IE+ NK G TPLL ++ ++Q +V+FL+K +AN++A+D +
Sbjct: 282 YAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRY 341
Query: 299 KRTALILAVQHNLSSIVTLLLQQNIHISSQDMFGQTAEDYAFCCDLRSIQQQILEHKNKM 358
RTALILAV +SIV+LLL+QNI +SSQD+ GQTA +YA I Q + ++K K
Sbjct: 342 GRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSRHNVICQLLSDYKEKQ 401
Query: 359 LKNHLRNDNQETAAMKPENLKKRKKRKKLKKRKEGAKAEHNLKVASEEKQERLERSENKQ 418
+ LK E + E +LK+ SEE+ +RL+ SEN Q
Sbjct: 402 I---------------------------LKVSSENSNPEQDLKLTSEEESQRLKGSENSQ 434
Query: 419 PQD 421
P++
Sbjct: 435 PEE 437
>gi|52856434 POTE ankyrin domain family, member G [Homo sapiens]
Length = 508
Score = 243 bits (621), Expect = 7e-64
Identities = 132/303 (43%), Positives = 189/303 (62%), Gaps = 27/303 (8%)
Query: 119 DQEYAGRGYHIRDWELRKIHRAAIKGDAAEVEHCLTRRFRDLDVRDKKDRTVLHLACAHG 178
D + YH+R +L K+HRAA G + + + D++ +DK+ RT LHLA A+G
Sbjct: 125 DSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLKDTDMNKKDKQKRTALHLASANG 184
Query: 179 RVQVVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAIILLKRGANPNIKDIYGNTALH 238
+VV LLLDR+CQ+NI D RT L KAV C+E+ CA++LL+ G +PNI D YGNTALH
Sbjct: 185 NSEVVKLLLDRRCQLNILDNKKRTALTKAVQCREDECALMLLEHGTDPNIPDEYGNTALH 244
Query: 239 YAVYNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNF 298
YA+YNE +A+ LL + A+IE+ NK G TPLL ++ ++Q +V+FL+K +AN++A+D +
Sbjct: 245 YAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRY 304
Query: 299 KRTALILAVQHNLSSIVTLLLQQNIHISSQDMFGQTAEDYAFCCDLRSIQQQILEHKNKM 358
RTALILAV +SIV+LLL+QNI +SSQD+ GQTA +YA I Q + ++K K
Sbjct: 305 GRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHNVICQLLSDYKEKQ 364
Query: 359 LKNHLRNDNQETAAMKPENLKKRKKRKKLKKRKEGAKAEHNLKVASEEKQERLERSENKQ 418
+ LK E + E +LK+ SEE+ +RL+ SEN Q
Sbjct: 365 M---------------------------LKVSSENSNPEQDLKLTSEEESQRLKGSENSQ 397
Query: 419 PQD 421
P++
Sbjct: 398 PEE 400
>gi|224282147 prostate-specific P704P [Homo sapiens]
Length = 508
Score = 243 bits (620), Expect = 9e-64
Identities = 132/303 (43%), Positives = 188/303 (62%), Gaps = 27/303 (8%)
Query: 119 DQEYAGRGYHIRDWELRKIHRAAIKGDAAEVEHCLTRRFRDLDVRDKKDRTVLHLACAHG 178
D + YH+R +L K+HRAA G + + + D++ +DK+ RT LHLA A+G
Sbjct: 125 DSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLKDTDMNKKDKQKRTALHLASANG 184
Query: 179 RVQVVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAIILLKRGANPNIKDIYGNTALH 238
+VV LLLDR+CQ+NI D RT L KAV CQE+ CA++LL+ G +PNI D YGNTALH
Sbjct: 185 NSEVVKLLLDRRCQLNILDNKKRTALTKAVQCQEDECALMLLEHGTDPNIPDEYGNTALH 244
Query: 239 YAVYNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNF 298
YA+YNE +A+ LL + A+IE+ NK G TPLL ++ ++Q +V+FL+K +AN++A+D +
Sbjct: 245 YAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRY 304
Query: 299 KRTALILAVQHNLSSIVTLLLQQNIHISSQDMFGQTAEDYAFCCDLRSIQQQILEHKNKM 358
RT LILAV +SIV+LLL+QNI +SSQD+ GQTA +YA I Q + ++K K
Sbjct: 305 GRTVLILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSRHNVICQLLSDYKEKQ 364
Query: 359 LKNHLRNDNQETAAMKPENLKKRKKRKKLKKRKEGAKAEHNLKVASEEKQERLERSENKQ 418
+ LK E + E +LK+ SEE+ +RL+ SEN Q
Sbjct: 365 I---------------------------LKVSSENSNPEQDLKLTSEEESQRLKGSENSQ 397
Query: 419 PQD 421
P++
Sbjct: 398 PEE 400
>gi|113413200 PREDICTED: similar to protein expressed in prostate,
ovary, testis, and placenta 2 [Homo sapiens]
Length = 1038
Score = 243 bits (620), Expect = 9e-64
Identities = 188/626 (30%), Positives = 300/626 (47%), Gaps = 100/626 (15%)
Query: 119 DQEYAGRGYHIRDWELRKIHRAAIKGDAAEVEHCLTRRFRDLDVRDKKDRTVLHLACAHG 178
D + YH+R +L K+HRAA G A + + R D++ +DK+ RT LHLA A+G
Sbjct: 88 DSAFVEPRYHVRREDLDKLHRAAWWGKVARKDLIVMLRDTDVNKQDKQKRTALHLASANG 147
Query: 179 RVQVVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAIILLKRGANPNIKDIYGNTALH 238
VV LLLDR+CQ+N+ D RT L KAV CQE+ CA++LL+ G +PNI D YGNT LH
Sbjct: 148 NSGVVKLLLDRRCQLNVLDNKKRTALTKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLH 207
Query: 239 YAVYNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNF 298
YA+YNE +A+ LL + A+IE+ NK G TPLL ++ ++Q +V+FL+K +AN++A+D +
Sbjct: 208 YAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRY 267
Query: 299 KRTALILAVQHNLSSIVTLLLQQNIHISSQDMFGQTAEDYAFCCDLRSIQQQILEHKNKM 358
RTALILAV +SIV+LLL+QNI +SSQD+ GQTA +YA I Q + ++K K
Sbjct: 268 GRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQ 327
Query: 359 LKNHLRNDNQETAAMKPENLKKRKKRKKLKKRKEGAKAEHNLKVASEEKQERLERSENKQ 418
+ LK E + E +LK+ SEE+ +R + SEN Q
Sbjct: 328 M---------------------------LKISSENSNPEQDLKLTSEEESQRFKGSENSQ 360
Query: 419 PQ---DSQSYGKKKDEMFGNFMLKRD---IAMLKEELYAIK----NDSLRKEKK------ 462
P+ K D M K + + +L+ + +D L ++K
Sbjct: 361 PEKMSQEPEINKDGDREVEEEMKKHESNNVGLLENLSNGVTAGNGDDGLIPQRKSRTPEN 420
Query: 463 ------YIQEIKSITEI---------------NANFEKSVRLNEEMITKKVAQYSQQLND 501
+E I E+ N+N E+ ++L E ++++ +
Sbjct: 421 QQFPDNESEEYHRICELVSDYKEKQMPKYSSENSNPEQDLKLTSEEESQRLKGSENGQPE 480
Query: 502 LKAENARLNSKLEKEKHNKERLEAEVE--SLH-------SNLATAIN------------- 539
+++ +N ++E N +E + S H +N ATA N
Sbjct: 481 KRSQEPEINKDGDRELENFMAIEEMKKHGSTHVGFPENLTNGATAGNGDDGLIPPRKSRT 540
Query: 540 -EYNEILERKDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKARVKFNT-LKGK 597
E + + ++ E +D + N L D+ + E+ + K N+ L
Sbjct: 541 PESQQFPDTENEEYHSDEQNDTQKQFCEEQNTGILHDEILIHEEKQIEVVEKMNSELSLS 600
Query: 598 LRETRDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAKESQSIGKQNSSEERIRQR 657
++ RD L E ++ E + + L+ +K Q+ ++ +S+ K+N
Sbjct: 601 CKKERDFLHENSMLREEIAM-LRLELDTMKHQSQLRKKKYLEDIESVKKKN--------- 650
Query: 658 ELENLLLERQLEDARKEGDNKEIVIN 683
+NLL QL + + D +VI+
Sbjct: 651 --DNLLKALQLNELTMDDDTAVLVID 674
>gi|134133226 protein expressed in prostate, ovary, testis, and
placenta 2 [Homo sapiens]
Length = 1075
Score = 242 bits (618), Expect = 2e-63
Identities = 135/313 (43%), Positives = 190/313 (60%), Gaps = 28/313 (8%)
Query: 119 DQEYAGRGYHIRDWELRKIHRAAIKGDAAEVEHCLTRRFRDLDVRDKKDRTVLHLACAHG 178
D + YH+R +L K+HRAA G + + R D++ +DK+ RT LHLA A+G
Sbjct: 125 DSAFMEPRYHVRGEDLDKLHRAAWWGKVPRKDLIVMLRDTDVNKKDKQKRTALHLASANG 184
Query: 179 RVQVVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAIILLKRGANPNIKDIYGNTALH 238
+VV LLLDR+CQ+N+ D RT L+KAV CQE+ CA++LL+ G +PNI D YGNT LH
Sbjct: 185 NSEVVKLLLDRRCQLNVLDNKKRTALIKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLH 244
Query: 239 YAVYNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNF 298
YA+YNE +A+ LL + A+IE+ NK G TPLL ++ ++Q +V+FL+K +AN++A+D +
Sbjct: 245 YAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRY 304
Query: 299 KRTALILAVQHNLSSIVTLLLQQNIHISSQDMFGQTAEDYAFCCDLRSIQQQILEHKNKM 358
RTALILAV +SIV+LLL+QNI +SSQD+ GQTA +YA I Q + ++K K
Sbjct: 305 GRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQ 364
Query: 359 LKNHLRNDNQETAAMKPENLKKRKKRKKLKKRKEGAKAEHNLKVASEEKQERLERSENKQ 418
+ LK E + E LK+ SEE+ +R + SEN Q
Sbjct: 365 M---------------------------LKISSENSNPEQELKLTSEEESQRFKGSENSQ 397
Query: 419 PQD-SQSYGKKKD 430
P+ SQ KD
Sbjct: 398 PEKMSQELEINKD 410
Score = 57.4 bits (137), Expect = 9e-08
Identities = 34/88 (38%), Positives = 55/88 (62%), Gaps = 2/88 (2%)
Query: 398 HNLKVASEEKQERLERSENKQPQDSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSL 457
H+ + EEKQ +E E + S S K+KD + N L+ +IAML+ EL +K+ S
Sbjct: 613 HDEILIHEEKQ--IEVVEKMNSELSLSCKKEKDVLHENSTLREEIAMLRLELDTMKHQSQ 670
Query: 458 RKEKKYIQEIKSITEINANFEKSVRLNE 485
+EKKY+++I+S+ + N N K+++LNE
Sbjct: 671 LREKKYLEDIESVKKKNDNLLKALQLNE 698
>gi|153791352 prostate, ovary, testis expressed protein on
chromosome 2 [Homo sapiens]
Length = 1075
Score = 242 bits (617), Expect = 2e-63
Identities = 131/302 (43%), Positives = 187/302 (61%), Gaps = 27/302 (8%)
Query: 119 DQEYAGRGYHIRDWELRKIHRAAIKGDAAEVEHCLTRRFRDLDVRDKKDRTVLHLACAHG 178
D + YH+R +L K+HRAA G + + R D++ +DK+ RT LHLA A+G
Sbjct: 125 DSAFMEPRYHVRGEDLDKLHRAAWWGKVPRKDLIVMLRDTDVNKQDKQKRTALHLASANG 184
Query: 179 RVQVVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAIILLKRGANPNIKDIYGNTALH 238
+VV LLLDR+CQ+N+ D RT L+KAV CQE+ CA++LL+ G +PNI D YGNT LH
Sbjct: 185 NSEVVKLLLDRRCQLNVLDNKKRTALIKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLH 244
Query: 239 YAVYNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNF 298
YA+YNE +A+ LL + A+IE+ NK G TPLL ++ ++Q +V+FL+K +AN++A+D +
Sbjct: 245 YAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRY 304
Query: 299 KRTALILAVQHNLSSIVTLLLQQNIHISSQDMFGQTAEDYAFCCDLRSIQQQILEHKNKM 358
RTALILAV +SIV+LLL+QNI +SSQD+ GQTA +YA I Q + ++K K
Sbjct: 305 GRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQ 364
Query: 359 LKNHLRNDNQETAAMKPENLKKRKKRKKLKKRKEGAKAEHNLKVASEEKQERLERSENKQ 418
+ LK E + E +LK+ SEE+ +R + SEN Q
Sbjct: 365 M---------------------------LKISSENSNPEQDLKLTSEEESQRFKGSENSQ 397
Query: 419 PQ 420
P+
Sbjct: 398 PE 399
Score = 57.0 bits (136), Expect = 1e-07
Identities = 34/88 (38%), Positives = 55/88 (62%), Gaps = 2/88 (2%)
Query: 398 HNLKVASEEKQERLERSENKQPQDSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSL 457
H+ + EEKQ +E E + S S K+KD + N L+ +IAML+ EL +K+ S
Sbjct: 613 HDEILIHEEKQ--IEVVEKMNSELSLSCKKEKDILHENSTLREEIAMLRLELDTMKHQSQ 670
Query: 458 RKEKKYIQEIKSITEINANFEKSVRLNE 485
+EKKY+++I+S+ + N N K+++LNE
Sbjct: 671 LREKKYLEDIESVKKRNDNLLKALQLNE 698
>gi|153792284 pote protein [Homo sapiens]
Length = 584
Score = 241 bits (616), Expect = 3e-63
Identities = 168/500 (33%), Positives = 264/500 (52%), Gaps = 65/500 (13%)
Query: 127 YHIRDWELRKIHRAAIKGDAAEVEHCLTRRFRDLDVRDKKDRTVLHLACAHGRVQVVTLL 186
YHIR +L K+HRAA G + + R D++ RDK+ RT LHLA A+G +VV LL
Sbjct: 133 YHIRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKEKRTALHLASANGNSEVVQLL 192
Query: 187 LDRKCQINICDRLNRTPLMKAVHCQEEACAIILLKRGANPNIKDIYGNTALHYAVYNEGT 246
LDR+CQ+N+ D RT L+KA+ CQE+ C ++LL+ GA+ NI D YGNTALHYA+YNE
Sbjct: 193 LDRRCQLNVLDNKKRTALIKAIQCQEDECVLMLLEHGADRNIPDEYGNTALHYAIYNEDK 252
Query: 247 SLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNFKRTALILA 306
+A+ LL + A+IE+ NK G TPLL ++ ++Q +V+FL+K +AN++ +D + RTALILA
Sbjct: 253 LMAKALLLYGADIESKNKCGLTPLLLGVHEQKQQVVKFLIKKKANLNVLDRYGRTALILA 312
Query: 307 VQHNLSSIVTLLLQQNIHISSQDMFGQTAEDYAFCCDLRSIQQQILEHKNKMLKNHLRND 366
V +SIV LLL+QN+ +SSQD+ GQTA +YA I + + ++K K +
Sbjct: 313 VCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDYKEKQM------- 365
Query: 367 NQETAAMKPENLKKRKKRKKLKKRKEGAKAEHNLKVASEEKQERLERSENKQPQDSQSYG 426
LK E + E +LK+ SEE+ +RL+ SEN QP+
Sbjct: 366 --------------------LKISSENSNPEQDLKLTSEEESQRLKVSENSQPE------ 399
Query: 427 KKKDEMFGNFMLKRDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEE 486
K E N R++ +EE+ KK+ + E N + ++
Sbjct: 400 KMSQEPEINKDCDREV---EEEI-----------KKHGSNPVGLPENLTNGASAGNGDDG 445
Query: 487 MITKKVAQYSQQLNDLKAENARLNSKLEKEKHNKERLEAEVESLHSNLATAINEYNEILE 546
+I ++ ++ K EN + +E H+ E+ + + L T I++ +EIL
Sbjct: 446 LIPQRRSR--------KPENQQFPDTENEEYHSDEQNDTR-KQLSEEQNTGISQ-DEILT 495
Query: 547 RKDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKARVKFNTLK-------GKLR 599
K ++ + S L +N +L E++ R++ + K K+
Sbjct: 496 NKQKQIEVAEQKMNSELSLSHKKEEDLLRENSVLQEEIAMLRLELDETKHQNQLRENKIL 555
Query: 600 ETRDALREKT-LALESVQLD 618
E ++++EKT L ++QL+
Sbjct: 556 EEIESVKEKTDKLLRAMQLN 575
>gi|239741769 PREDICTED: similar to protein expressed in prostate,
ovary, testis, and placenta 2 [Homo sapiens]
Length = 952
Score = 241 bits (616), Expect = 3e-63
Identities = 132/302 (43%), Positives = 186/302 (61%), Gaps = 27/302 (8%)
Query: 119 DQEYAGRGYHIRDWELRKIHRAAIKGDAAEVEHCLTRRFRDLDVRDKKDRTVLHLACAHG 178
D + YH+R +L K+HRAA G A + + R D++ +DK+ RT LHLA A+G
Sbjct: 125 DSAFVEPRYHVRREDLDKLHRAAWWGKVARKDLIVMLRDTDVNKQDKQKRTALHLASANG 184
Query: 179 RVQVVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAIILLKRGANPNIKDIYGNTALH 238
VV LLLDR+CQ+N+ D RT L KAV CQE+ CA++LL+ G +PNI D YGNT LH
Sbjct: 185 NSGVVKLLLDRRCQLNVLDNKKRTALTKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLH 244
Query: 239 YAVYNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNF 298
YA+YNE +A+ LL + A+IE+ NK G TPLL ++ ++Q +V+FL+K +AN++A+D +
Sbjct: 245 YAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRY 304
Query: 299 KRTALILAVQHNLSSIVTLLLQQNIHISSQDMFGQTAEDYAFCCDLRSIQQQILEHKNKM 358
RTALILAV +SIV+LLL+QNI +SSQD+ GQTA +YA I Q + ++K K
Sbjct: 305 GRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQ 364
Query: 359 LKNHLRNDNQETAAMKPENLKKRKKRKKLKKRKEGAKAEHNLKVASEEKQERLERSENKQ 418
+ LK E + E +LK+ SEE+ +R + SEN Q
Sbjct: 365 M---------------------------LKISSENSNPEQDLKLTSEEESQRFKGSENSQ 397
Query: 419 PQ 420
P+
Sbjct: 398 PE 399
>gi|88953571 PREDICTED: similar to protein expressed in prostate,
ovary, testis, and placenta 2 isoform 2 [Homo sapiens]
Length = 1075
Score = 241 bits (616), Expect = 3e-63
Identities = 132/302 (43%), Positives = 186/302 (61%), Gaps = 27/302 (8%)
Query: 119 DQEYAGRGYHIRDWELRKIHRAAIKGDAAEVEHCLTRRFRDLDVRDKKDRTVLHLACAHG 178
D + YH+R +L K+HRAA G A + + R D++ +DK+ RT LHLA A+G
Sbjct: 125 DSAFVEPRYHVRREDLDKLHRAAWWGKVARKDLIVMLRDTDVNKQDKQKRTALHLASANG 184
Query: 179 RVQVVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAIILLKRGANPNIKDIYGNTALH 238
VV LLLDR+CQ+N+ D RT L KAV CQE+ CA++LL+ G +PNI D YGNT LH
Sbjct: 185 NSGVVKLLLDRRCQLNVLDNKKRTALTKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLH 244
Query: 239 YAVYNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNF 298
YA+YNE +A+ LL + A+IE+ NK G TPLL ++ ++Q +V+FL+K +AN++A+D +
Sbjct: 245 YAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRY 304
Query: 299 KRTALILAVQHNLSSIVTLLLQQNIHISSQDMFGQTAEDYAFCCDLRSIQQQILEHKNKM 358
RTALILAV +SIV+LLL+QNI +SSQD+ GQTA +YA I Q + ++K K
Sbjct: 305 GRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQ 364
Query: 359 LKNHLRNDNQETAAMKPENLKKRKKRKKLKKRKEGAKAEHNLKVASEEKQERLERSENKQ 418
+ LK E + E +LK+ SEE+ +R + SEN Q
Sbjct: 365 M---------------------------LKISSENSNPEQDLKLTSEEESQRFKGSENSQ 397
Query: 419 PQ 420
P+
Sbjct: 398 PE 399
Score = 68.2 bits (165), Expect = 5e-11
Identities = 104/530 (19%), Positives = 200/530 (37%), Gaps = 66/530 (12%)
Query: 128 HIRDWELRKIHRAAIKGDAAEVEHCLTRRFRDLDVRDKKDRTVLHLACAHGRVQVVTLLL 187
++ D + R A++ E L D ++ D+ T LH A + + LL
Sbjct: 200 NVLDNKKRTALTKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLHYAIYNEDKLMAKALL 259
Query: 188 DRKCQINICDRLNRTPLMKAVHCQEEACAIILLKRGANPNIKDIYGNTALHYAVYNEGTS 247
I ++ TPL+ VH Q++ L+K+ AN N D YG TAL AV S
Sbjct: 260 LYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSAS 319
Query: 248 LAERLLSHHANIEALNKEGNTPLLFAINSRR----QHMVEFLLKNQANIHAVDNFKRTAL 303
+ LL + ++ + + G T +A++S Q + ++ K I + ++ L
Sbjct: 320 IVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQMLKISSENSNPEQDL 379
Query: 304 ILAVQHNLSSIVTLLLQQNIHISSQDMFGQTAEDYAFCCDLRSIQQQILEHKN------K 357
L + Q +S + + + R +++++ +H++ +
Sbjct: 380 KLTSEEESQRFKGSENSQPEKMSQEPEINKDGD--------REVEEEMKKHESNNVGLLE 431
Query: 358 MLKNHLRNDNQETAAMK------PEN-----------------LKKRKKRKKLKKRKEGA 394
L N + N + + PEN + K+++ K E +
Sbjct: 432 NLSNGVTAGNGDDGLIPQRKSRTPENQQFPDNESEEYHRICELVSDYKEKQMPKYSSENS 491
Query: 395 KAEHNLKVASEEKQERLERSENKQPQ---DSQSYGKKKDEMFGNFMLKRDIAMLKEELYA 451
E +LK+ SEE+ +RL+ SEN QP+ K D NFM
Sbjct: 492 NPEQDLKLTSEEESQRLKGSENGQPEKRSQEPEINKDGDRELENFM-------------- 537
Query: 452 IKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEEMITKKVAQYSQQLNDLKAENARLNS 511
++ + KK+ E N + ++ +I + ++ + EN +S
Sbjct: 538 ----AIEEMKKHGSTHVGFPENLTNGATAGNGDDGLIPPRKSRTPESQQFPDTENEEYHS 593
Query: 512 KLEKEKHNKERLEAEVESLHSNLATAINEYNEILERKDLELVL---WRADDVSRHETMGS 568
+ + + E LH + + E++E+ + EL L D + + T+
Sbjct: 594 DEQNDTQKQFCEEQNTGILHDEILIHEEKQIEVVEKMNSELSLSCKKEKDFLHENSTLRE 653
Query: 569 NISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKTLALESVQLD 618
I+ L + + + Q + K+ +++ D L K L L + +D
Sbjct: 654 EIAMLRLELDTMKHQSQLRKKKYLEDIESVKKKNDNLL-KALQLNELTMD 702
>gi|239741279 PREDICTED: similar to FLJ00310 protein [Homo sapiens]
Length = 561
Score = 241 bits (616), Expect = 3e-63
Identities = 202/582 (34%), Positives = 271/582 (46%), Gaps = 169/582 (29%)
Query: 388 KKRKEGAKAEHNLKVASEEKQERLERSENKQPQDSQSYGKKKDEMFGNFMLKRDIAMLKE 447
+K + +AE L VA EE+QER ERSE KQ Q + K E L ++
Sbjct: 141 RKNVQTLRAEQTLPVALEEEQERCERSEKKQSQVKEGNNTNKSE---KIQLSENVCHSTS 197
Query: 448 ELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEEMITKKVAQYSQQLNDLKAENA 507
A D L K++K + Y QQ
Sbjct: 198 SAAA---DRLTKQRKVGKT----------------------------YPQQFP------- 219
Query: 508 RLNSKLEKEKHNKERLEAEVESLHSNLATAINEYNEILERKDLELVLWRADDVSRHETMG 567
KL+KE H++E LE + + +Y + +E K LE + D
Sbjct: 220 ---KKLKKE-HDREELERKEK-----------QYKKEVEAKQLEPTVQSLD--------- 255
Query: 568 SNISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALR---EKTLALESVQLDLKQAQH 624
+K T + + +LR +K + + DL Q Q
Sbjct: 256 ---------------------MKLKTTRNTPNQINQSLRYSQKKVIGFRNSPNDLSQTQQ 294
Query: 625 RIKEMKQMHPNGEAKESQSIGKQNSSEERIRQRELENLLLERQLEDARKEGDNKEIVINI 684
+IKEMK+M+ N EAK + S GK + EERI Q + EN +E+QL+D ++ D
Sbjct: 295 QIKEMKEMYENAEAKVNNSTGKWSCVEERICQLQHENPCIEQQLDDVHQKED-------- 346
Query: 685 HRDCLENGKEDLLEERNKELMNEYNYLKEKLLQYEKEKAEREVIVREFQEELVDHLKKFS 744
H++ + N + +E K+LM E K K L E DHLK+
Sbjct: 347 HKEIVTNIQRGFIESGKKDLMLEE---KNKKLMNE-----------------CDHLKE-- 384
Query: 745 MSESPLEGTSHCHINLDETWTSKKKLFQVEIQPEEKHEEFRKVFELISLLNYTADQIRKK 804
LFQ E EK E V
Sbjct: 385 ------------------------SLFQYE---REKAERVVVV----------------- 400
Query: 805 NRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFDDLMAE 864
R+L++EA K L M + L ++ H +L+ Q+ LF+ ++ +FDD MAE
Sbjct: 401 -RQLQQEAADSLKKLTMLESPLEGISHY----HINLDETQVPKKKLFQ-VESQFDDFMAE 454
Query: 865 KEAVSSKCVNLAKDNEVLHQELLSMGKVQEKCEKLEKDKKMLEEKVLNLKTHMEKDMVEL 924
KEAVSSKCVNLAK+ +V QELLSM KVQ++CEKLE+DKKMLEE++LNLKTHME MVEL
Sbjct: 455 KEAVSSKCVNLAKEIQVFQQELLSMKKVQQECEKLEEDKKMLEEEILNLKTHMENSMVEL 514
Query: 925 GKVQEYKSELDERAMQAIEKLEEIHLQKQAEYEKQLEQLNKD 966
K+QEYKSELDERAMQA+EKLEEIHLQ+QAE++KQLEQLNKD
Sbjct: 515 SKLQEYKSELDERAMQAVEKLEEIHLQEQAEHKKQLEQLNKD 556
Score = 35.0 bits (79), Expect = 0.49
Identities = 70/332 (21%), Positives = 131/332 (39%), Gaps = 50/332 (15%)
Query: 767 KKKLFQVEIQPEEKHEEFRKVFELISLLNYTADQIRKKNRELEEEATGYKKCLEMTINML 826
K+K ++ E++ ++ + + + T +QI + R +++ G++
Sbjct: 234 KEKQYKKEVEAKQLEPTVQSLDMKLKTTRNTPNQINQSLRYSQKKVIGFRN--------- 284
Query: 827 NAFANEDFSCHGDLNTDQLK-MDILFKKLKQKFDDLMAEKEAVSSKCVNLAKDNEVLHQE 885
+ D S Q+K M +++ + K ++ + V + L +N + Q+
Sbjct: 285 ---SPNDLS----QTQQQIKEMKEMYENAEAKVNNSTGKWSCVEERICQLQHENPCIEQQ 337
Query: 886 LLSMGKVQEKCEK--------LEKDKK--MLEEKVLNLKTHMEKDMVELGKVQEYKSELD 935
L + + ++ E +E KK MLEEK N K E D ++ Q Y+ E
Sbjct: 338 LDDVHQKEDHKEIVTNIQRGFIESGKKDLMLEEK--NKKLMNECDHLKESLFQ-YEREKA 394
Query: 936 ERAMQAIEKLEEI--HLQKQAEYEKQLE-----QLNKDNTASLKKKELTLKDVECKFSKM 988
ER + + +E L+K E LE +N D T KKK ++ F
Sbjct: 395 ERVVVVRQLQQEAADSLKKLTMLESPLEGISHYHINLDETQVPKKKLFQVESQFDDFMAE 454
Query: 989 KTAYEDVTTELEEYKEAFAVALKANSSMSEKITK--SDKKI---AVISTKLFMEK----- 1038
K A L + + F L + + ++ K DKK+ +++ K ME
Sbjct: 455 KEAVSSKCVNLAKEIQVFQQELLSMKKVQQECEKLEEDKKMLEEEILNLKTHMENSMVEL 514
Query: 1039 ERMEYFLSTLPMRPDPELPCVENLNSIELNRK 1070
+++ + S L R + VE L I L +
Sbjct: 515 SKLQEYKSELDER---AMQAVEKLEEIHLQEQ 543
Score = 32.3 bits (72), Expect = 3.2
Identities = 80/382 (20%), Positives = 160/382 (41%), Gaps = 62/382 (16%)
Query: 373 MKPENLKKRKKRKKLKKRKEGAKAEHNLKVASEEKQERLERSENKQPQDSQSYGKKKDEM 432
+K E+ ++ +RK+ + +KE + V S + + + R+ Q S Y +KK
Sbjct: 222 LKKEHDREELERKEKQYKKEVEAKQLEPTVQSLDMKLKTTRNTPNQINQSLRYSQKKVIG 281
Query: 433 FGNFMLKRDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEEMITKKV 492
F N ND + + Q+IK + E+ N E V + T K
Sbjct: 282 FRN----------------SPNDLSQTQ----QQIKEMKEMYENAEAKVNNS----TGKW 317
Query: 493 AQYSQQLNDLKAENARLNSKLEKEKHNKERLEAEVESLHSNLATAINEYNEILERKDLEL 552
+ +++ L+ EN + +L+ + H KE H + T I +KDL L
Sbjct: 318 SCVEERICQLQHENPCIEQQLD-DVHQKED--------HKEIVTNIQRGFIESGKKDLML 368
Query: 553 VLWRADDVSRHETMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKTL-- 610
E +++ E L + + + ++ +E D+L++ T+
Sbjct: 369 ----------EEKNKKLMNECDHLKESLFQYEREKAERVVVVRQLQQEAADSLKKLTMLE 418
Query: 611 ----ALESVQLDLKQAQHRIKEMKQMHPNGE----AKESQSIGKQNSSEE-RIRQRELEN 661
+ ++L + Q K++ Q+ + KE+ S N ++E ++ Q+EL +
Sbjct: 419 SPLEGISHYHINLDETQVPKKKLFQVESQFDDFMAEKEAVSSKCVNLAKEIQVFQQELLS 478
Query: 662 LLLERQLEDARKEGDNK---EIVINIHRDCLENGKEDL--LEERNKELMNEYNYLKEKLL 716
+ +Q E + E D K E ++N+ + +EN +L L+E EL EKL
Sbjct: 479 MKKVQQ-ECEKLEEDKKMLEEEILNL-KTHMENSMVELSKLQEYKSELDERAMQAVEKLE 536
Query: 717 Q-YEKEKAEREVIVREFQEELV 737
+ + +E+AE + + + ++++
Sbjct: 537 EIHLQEQAEHKKQLEQLNKDII 558
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.130 0.370
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 50,891,531
Number of Sequences: 37866
Number of extensions: 2495794
Number of successful extensions: 28756
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 589
Number of HSP's successfully gapped in prelim test: 1246
Number of HSP's that attempted gapping in prelim test: 14217
Number of HSP's gapped (non-prelim): 8525
length of query: 1363
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1248
effective length of database: 13,892,928
effective search space: 17338374144
effective search space used: 17338374144
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.