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Search of human proteins with 118600995
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|118600995 cripto, FRL-1, cryptic family 1B [Homo sapiens]
(223 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|118600995 cripto, FRL-1, cryptic family 1B [Homo sapiens] 487 e-138
gi|14211837 cryptic [Homo sapiens] 482 e-136
gi|4507425 teratocarcinoma-derived growth factor 1 [Homo sapiens] 92 5e-19
gi|169164915 PREDICTED: similar to hCG1644233 [Homo sapiens] 76 3e-14
gi|169163540 PREDICTED: similar to hCG1644233 [Homo sapiens] 76 3e-14
gi|222352166 nel-like 1 isoform 2 precursor [Homo sapiens] 54 1e-07
gi|148833508 notch1 preproprotein [Homo sapiens] 49 3e-06
gi|222352164 nel-like 1 isoform 1 precursor [Homo sapiens] 48 8e-06
gi|223029476 NEL-like protein 2 isoform d [Homo sapiens] 44 1e-04
gi|223029474 NEL-like protein 2 isoform c [Homo sapiens] 44 1e-04
gi|223029472 NEL-like protein 2 isoform b precursor [Homo sapiens] 44 1e-04
gi|223029470 NEL-like protein 2 isoform a [Homo sapiens] 44 1e-04
gi|5453766 NEL-like protein 2 isoform b precursor [Homo sapiens] 44 1e-04
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 43 2e-04
gi|110347437 latent transforming growth factor beta binding prot... 42 3e-04
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 42 5e-04
gi|21704279 jagged 2 isoform b precursor [Homo sapiens] 42 5e-04
gi|21704277 jagged 2 isoform a precursor [Homo sapiens] 42 5e-04
gi|4885631 tyrosine kinase with immunoglobulin-like and EGF-like... 41 7e-04
gi|224451128 eyes shut homolog isoform 1 [Homo sapiens] 41 0.001
gi|165932370 FAT tumor suppressor homolog 4 [Homo sapiens] 41 0.001
gi|88702793 slit-like 2 [Homo sapiens] 41 0.001
gi|134244285 Notch homolog 3 [Homo sapiens] 40 0.001
gi|110347412 latent transforming growth factor beta binding prot... 40 0.001
gi|110347431 latent transforming growth factor beta binding prot... 40 0.001
gi|41393583 EGF-like-domain, multiple 7 [Homo sapiens] 40 0.002
gi|7705889 EGF-like-domain, multiple 7 [Homo sapiens] 40 0.002
gi|122937283 6720455I24Rik homolog [Homo sapiens] 40 0.002
gi|209571555 von Willebrand factor D and EGF domains [Homo sapiens] 40 0.002
gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens] 40 0.002
>gi|118600995 cripto, FRL-1, cryptic family 1B [Homo sapiens]
Length = 223
Score = 487 bits (1254), Expect = e-138
Identities = 223/223 (100%), Positives = 223/223 (100%)
Query: 1 MTWRHHVRLLFTVSLALQIINLGNSYQREKHNGGREEVTKVATQKHRQSPLNWTSSHFGE 60
MTWRHHVRLLFTVSLALQIINLGNSYQREKHNGGREEVTKVATQKHRQSPLNWTSSHFGE
Sbjct: 1 MTWRHHVRLLFTVSLALQIINLGNSYQREKHNGGREEVTKVATQKHRQSPLNWTSSHFGE 60
Query: 61 VTGSAEGWGPEEPLPYSWAFGEGASARPRCCRNGGTCVLGSFCVCPAHFTGRYCEHDQRR 120
VTGSAEGWGPEEPLPYSWAFGEGASARPRCCRNGGTCVLGSFCVCPAHFTGRYCEHDQRR
Sbjct: 61 VTGSAEGWGPEEPLPYSWAFGEGASARPRCCRNGGTCVLGSFCVCPAHFTGRYCEHDQRR 120
Query: 121 SECGALEHGAWTLRACHLCRCIFGALHCLPLQTPDRCDPKDFLASHAHGPSAGGAPSLLL 180
SECGALEHGAWTLRACHLCRCIFGALHCLPLQTPDRCDPKDFLASHAHGPSAGGAPSLLL
Sbjct: 121 SECGALEHGAWTLRACHLCRCIFGALHCLPLQTPDRCDPKDFLASHAHGPSAGGAPSLLL 180
Query: 181 LLPCALLHRLLRPDAPAHPRSLVPSVLQRERRPCGRPGLGHRL 223
LLPCALLHRLLRPDAPAHPRSLVPSVLQRERRPCGRPGLGHRL
Sbjct: 181 LLPCALLHRLLRPDAPAHPRSLVPSVLQRERRPCGRPGLGHRL 223
>gi|14211837 cryptic [Homo sapiens]
Length = 223
Score = 482 bits (1240), Expect = e-136
Identities = 222/223 (99%), Positives = 222/223 (99%)
Query: 1 MTWRHHVRLLFTVSLALQIINLGNSYQREKHNGGREEVTKVATQKHRQSPLNWTSSHFGE 60
MTWRHHVRLLFTVSLALQIINLGNSYQREKHNGGREEVTKVATQKHRQSPLNWTSSHFGE
Sbjct: 1 MTWRHHVRLLFTVSLALQIINLGNSYQREKHNGGREEVTKVATQKHRQSPLNWTSSHFGE 60
Query: 61 VTGSAEGWGPEEPLPYSWAFGEGASARPRCCRNGGTCVLGSFCVCPAHFTGRYCEHDQRR 120
VTGSAEGWGPEEPLPYS AFGEGASARPRCCRNGGTCVLGSFCVCPAHFTGRYCEHDQRR
Sbjct: 61 VTGSAEGWGPEEPLPYSRAFGEGASARPRCCRNGGTCVLGSFCVCPAHFTGRYCEHDQRR 120
Query: 121 SECGALEHGAWTLRACHLCRCIFGALHCLPLQTPDRCDPKDFLASHAHGPSAGGAPSLLL 180
SECGALEHGAWTLRACHLCRCIFGALHCLPLQTPDRCDPKDFLASHAHGPSAGGAPSLLL
Sbjct: 121 SECGALEHGAWTLRACHLCRCIFGALHCLPLQTPDRCDPKDFLASHAHGPSAGGAPSLLL 180
Query: 181 LLPCALLHRLLRPDAPAHPRSLVPSVLQRERRPCGRPGLGHRL 223
LLPCALLHRLLRPDAPAHPRSLVPSVLQRERRPCGRPGLGHRL
Sbjct: 181 LLPCALLHRLLRPDAPAHPRSLVPSVLQRERRPCGRPGLGHRL 223
>gi|4507425 teratocarcinoma-derived growth factor 1 [Homo sapiens]
Length = 188
Score = 91.7 bits (226), Expect = 5e-19
Identities = 36/69 (52%), Positives = 42/69 (60%)
Query: 90 CCRNGGTCVLGSFCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACHLCRCIFGALHCL 149
CC NGGTC+LGSFC CP F GR CEHD R+ CG++ H W + C LC+C G L C
Sbjct: 82 CCLNGGTCMLGSFCACPPSFYGRNCEHDVRKENCGSVPHDTWLPKKCSLCKCWHGQLRCF 141
Query: 150 PLQTPDRCD 158
P CD
Sbjct: 142 PQAFLPGCD 150
>gi|169164915 PREDICTED: similar to hCG1644233 [Homo sapiens]
Length = 195
Score = 75.9 bits (185), Expect = 3e-14
Identities = 31/69 (44%), Positives = 38/69 (55%)
Query: 90 CCRNGGTCVLGSFCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACHLCRCIFGALHCL 149
CC NGGTC+LGSFC C F G CEH R+ CG++ H + C +C+C G L C
Sbjct: 101 CCLNGGTCMLGSFCACLPSFYGWNCEHGVRKENCGSVPHDTRLPKKCSMCKCWHGQLRCF 160
Query: 150 PLQTPDRCD 158
P CD
Sbjct: 161 PQAFLPGCD 169
>gi|169163540 PREDICTED: similar to hCG1644233 [Homo sapiens]
Length = 195
Score = 75.9 bits (185), Expect = 3e-14
Identities = 31/69 (44%), Positives = 38/69 (55%)
Query: 90 CCRNGGTCVLGSFCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACHLCRCIFGALHCL 149
CC NGGTC+LGSFC C F G CEH R+ CG++ H + C +C+C G L C
Sbjct: 101 CCLNGGTCMLGSFCACLPSFYGWNCEHGVRKENCGSVPHDTRLPKKCSMCKCWHGQLRCF 160
Query: 150 PLQTPDRCD 158
P CD
Sbjct: 161 PQAFLPGCD 169
>gi|222352166 nel-like 1 isoform 2 precursor [Homo sapiens]
Length = 763
Score = 53.5 bits (127), Expect = 1e-07
Identities = 27/59 (45%), Positives = 30/59 (50%), Gaps = 5/59 (8%)
Query: 81 GEGASARPRC---CRNGGTCVLGSFCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRAC 136
G G R C CR GGTCV + CVCP+ FTG +CE D EC H W AC
Sbjct: 510 GNGTICRAFCEEGCRYGGTCVAPNKCVCPSGFTGSHCEKD--IDECALRTHTCWNDSAC 566
Score = 28.9 bits (63), Expect = 3.7
Identities = 11/25 (44%), Positives = 15/25 (60%), Gaps = 1/25 (4%)
Query: 131 WTLRACHLCRCIFGALHCLPLQTPD 155
WT +C CRC+ G + C PL P+
Sbjct: 662 WT-HSCQQCRCLEGEVDCWPLTCPN 685
>gi|148833508 notch1 preproprotein [Homo sapiens]
Length = 2555
Score = 48.9 bits (115), Expect = 3e-06
Identities = 25/54 (46%), Positives = 28/54 (51%), Gaps = 3/54 (5%)
Query: 91 CRNGGTCVLG--SF-CVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACHLCRC 141
C NGGTCV G SF C+CP FTG YC+HD + HG C RC
Sbjct: 992 CFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRC 1045
Score = 42.0 bits (97), Expect = 4e-04
Identities = 22/50 (44%), Positives = 27/50 (54%), Gaps = 10/50 (20%)
Query: 83 GASARPRCCRNGGTCVLGS------FCVCPAHFTGRYCEHDQRRSECGAL 126
G +P C+NGGTC + S C CPA F G CE+D R CG+L
Sbjct: 1310 GCKGKP--CKNGGTCAVASNTARGFICKCPAGFEGATCENDAR--TCGSL 1355
Score = 40.4 bits (93), Expect = 0.001
Identities = 27/77 (35%), Positives = 33/77 (42%), Gaps = 10/77 (12%)
Query: 87 RPRCCRNGGTCVLG---SFCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRAC---HLCR 140
RP C NGG+C G +FC C F G +CE D +GA C + C
Sbjct: 912 RPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGA-NCTDCVDSYTCT 970
Query: 141 CI--FGALHCLPLQTPD 155
C F +HC TPD
Sbjct: 971 CPAGFSGIHC-ENNTPD 986
Score = 38.5 bits (88), Expect = 0.005
Identities = 22/63 (34%), Positives = 28/63 (44%), Gaps = 11/63 (17%)
Query: 91 CRNGGTCVLGSF---CVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACH------LCRC 141
C+NGG CV G C CP +TG+YC D EC + + CH C C
Sbjct: 266 CKNGGACVDGVNTYNCRCPPEWTGQYCTEDV--DECQLMPNACQNGGTCHNTHGGYNCVC 323
Query: 142 IFG 144
+ G
Sbjct: 324 VNG 326
Score = 37.7 bits (86), Expect = 0.008
Identities = 26/64 (40%), Positives = 29/64 (45%), Gaps = 7/64 (10%)
Query: 74 LPYSWAFGEG--ASARPRCCRNGGTCVLG----SF-CVCPAHFTGRYCEHDQRRSECGAL 126
LPY+ A E A P CRNGG C SF CVCP + G+ CE D
Sbjct: 819 LPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPC 878
Query: 127 EHGA 130
HGA
Sbjct: 879 RHGA 882
Score = 37.7 bits (86), Expect = 0.008
Identities = 25/84 (29%), Positives = 29/84 (34%), Gaps = 15/84 (17%)
Query: 91 CRNGGTCVLGSF---CVCPAHFTGRYCEHDQRRSECGALEHGAWTLRAC----------- 136
C+NGG C C CP+ +TG YC+ E A G R C
Sbjct: 1068 CKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGN 1127
Query: 137 -HLCRCIFGALHCLPLQTPDRCDP 159
H CRC G D C P
Sbjct: 1128 THHCRCQAGYTGSYCEDLVDECSP 1151
Score = 35.4 bits (80), Expect = 0.039
Identities = 23/64 (35%), Positives = 30/64 (46%), Gaps = 6/64 (9%)
Query: 87 RPRCCRNGGTC--VLGSF-CVCPAHFTGRYCEHDQRRSECGALEHGAW---TLRACHLCR 140
+P CR+GGTC +GS+ CVC A TG CE ++G T H C
Sbjct: 185 KPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECA 244
Query: 141 CIFG 144
C+ G
Sbjct: 245 CLPG 248
Score = 34.3 bits (77), Expect = 0.088
Identities = 23/66 (34%), Positives = 26/66 (39%), Gaps = 13/66 (19%)
Query: 88 PRCCRNGGTCVL---GSFCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACH------L 138
P C+NGGTC G CVC +TG C + A HGA CH
Sbjct: 303 PNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGA----TCHDRVASFY 358
Query: 139 CRCIFG 144
C C G
Sbjct: 359 CECPHG 364
Score = 33.5 bits (75), Expect = 0.15
Identities = 22/76 (28%), Positives = 32/76 (42%), Gaps = 9/76 (11%)
Query: 91 CRNGGTCV--LGSF-CVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACHLCRCI----F 143
C + G C+ + F C CP FTG C++D ++GA L + C+ +
Sbjct: 499 CLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGY 558
Query: 144 GALHCLPLQTPDRCDP 159
HC D CDP
Sbjct: 559 TGTHC--EVDIDECDP 572
Score = 33.1 bits (74), Expect = 0.20
Identities = 20/65 (30%), Positives = 30/65 (46%), Gaps = 7/65 (10%)
Query: 91 CRNGGTCV--LGSF-CVCPAHFTGRYCEHDQRRSECGALEHG--AWTLRACHLCRCIFG- 144
C +GGTC GS+ C CP +TG C++ + ++G W + C C G
Sbjct: 1030 CLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGW 1089
Query: 145 -ALHC 148
L+C
Sbjct: 1090 TGLYC 1094
Score = 32.0 bits (71), Expect = 0.44
Identities = 19/56 (33%), Positives = 26/56 (46%), Gaps = 5/56 (8%)
Query: 91 CRNGGTCVLGSF----CVCPAHFTGRYCEH-DQRRSECGALEHGAWTLRACHLCRC 141
CRNGGTC L + C CP ++G+ C+ D S A A ++C C
Sbjct: 111 CRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFEASYICHC 166
Score = 32.0 bits (71), Expect = 0.44
Identities = 15/30 (50%), Positives = 17/30 (56%), Gaps = 3/30 (10%)
Query: 91 CRNGGTCV--LGSF-CVCPAHFTGRYCEHD 117
C N GTCV +G + C CP F G CE D
Sbjct: 1238 CFNNGTCVDQVGGYSCTCPPGFVGERCEGD 1267
Score = 30.4 bits (67), Expect = 1.3
Identities = 13/28 (46%), Positives = 16/28 (57%), Gaps = 3/28 (10%)
Query: 91 CRNGGTCVLG---SFCVCPAHFTGRYCE 115
C NGGTC+ G C+C FTG C+
Sbjct: 1357 CLNGGTCISGPRSPTCLCLGPFTGPECQ 1384
Score = 30.0 bits (66), Expect = 1.7
Identities = 20/75 (26%), Positives = 25/75 (33%), Gaps = 12/75 (16%)
Query: 91 CRNGGTCVLG-----SFCVCPAHFTGRYCEHDQRRSECGA--LEHGAWTLRACHLCRCIF 143
C G C + C CP+ +TG C D GA EH + C
Sbjct: 381 CNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFEC-- 438
Query: 144 GALHCLPLQTPDRCD 158
CL T RC+
Sbjct: 439 ---QCLQGYTGPRCE 450
Score = 29.6 bits (65), Expect = 2.2
Identities = 14/34 (41%), Positives = 18/34 (52%), Gaps = 4/34 (11%)
Query: 88 PRCCRNGGTCV----LGSFCVCPAHFTGRYCEHD 117
P C+NGGTC + C C FTG+ CE +
Sbjct: 224 PSPCQNGGTCRPTGDVTHECACLPGFTGQNCEEN 257
Score = 28.1 bits (61), Expect = 6.3
Identities = 14/43 (32%), Positives = 17/43 (39%), Gaps = 3/43 (6%)
Query: 91 CRNGGTC---VLGSFCVCPAHFTGRYCEHDQRRSECGALEHGA 130
C NGGTC + G C CP + C + HGA
Sbjct: 687 CHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGA 729
Score = 27.7 bits (60), Expect = 8.2
Identities = 13/30 (43%), Positives = 17/30 (56%), Gaps = 3/30 (10%)
Query: 91 CRNGGTCVL---GSFCVCPAHFTGRYCEHD 117
CR+G +C G C C A ++GR CE D
Sbjct: 878 CRHGASCQNTHGGYRCHCQAGYSGRNCETD 907
>gi|222352164 nel-like 1 isoform 1 precursor [Homo sapiens]
Length = 810
Score = 47.8 bits (112), Expect = 8e-06
Identities = 29/74 (39%), Positives = 34/74 (45%), Gaps = 14/74 (18%)
Query: 81 GEGASARPRC---CRNGGTCVLGSFCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACH 137
G G R C CR GGTCV + CVCP+ FTG +CE D G +E CH
Sbjct: 510 GNGTICRAFCEEGCRYGGTCVAPNKCVCPSGFTGSHCEKDIDECSEGIIE--------CH 561
Query: 138 ---LCRCIFGALHC 148
C + G HC
Sbjct: 562 NHSRCVNLPGWYHC 575
Score = 28.9 bits (63), Expect = 3.7
Identities = 11/25 (44%), Positives = 15/25 (60%), Gaps = 1/25 (4%)
Query: 131 WTLRACHLCRCIFGALHCLPLQTPD 155
WT +C CRC+ G + C PL P+
Sbjct: 709 WT-HSCQQCRCLEGEVDCWPLTCPN 732
>gi|223029476 NEL-like protein 2 isoform d [Homo sapiens]
Length = 839
Score = 43.9 bits (102), Expect = 1e-04
Identities = 18/40 (45%), Positives = 22/40 (55%), Gaps = 3/40 (7%)
Query: 81 GEGASARPRC---CRNGGTCVLGSFCVCPAHFTGRYCEHD 117
G G + + C CRNGG C+ + C CP FTG CE D
Sbjct: 539 GNGTTCKAFCKDGCRNGGACIAANVCACPQGFTGPSCETD 578
Score = 32.0 bits (71), Expect = 0.44
Identities = 22/75 (29%), Positives = 30/75 (40%), Gaps = 11/75 (14%)
Query: 91 CRNGGTCVLGSFCVCPAHFTGRYC--EHDQRRSECGALEHG--------AWTLRACHLCR 140
C+NG C C +C E D R S ++G W ++ C CR
Sbjct: 688 CQNGFVMCRRMVCDCENPTVDLFCCPECDPRLSSQCLHQNGETLYNSGDTW-VQNCQQCR 746
Query: 141 CIFGALHCLPLQTPD 155
C+ G + C PL PD
Sbjct: 747 CLQGEVDCWPLPCPD 761
>gi|223029474 NEL-like protein 2 isoform c [Homo sapiens]
Length = 815
Score = 43.9 bits (102), Expect = 1e-04
Identities = 18/40 (45%), Positives = 22/40 (55%), Gaps = 3/40 (7%)
Query: 81 GEGASARPRC---CRNGGTCVLGSFCVCPAHFTGRYCEHD 117
G G + + C CRNGG C+ + C CP FTG CE D
Sbjct: 515 GNGTTCKAFCKDGCRNGGACIAANVCACPQGFTGPSCETD 554
Score = 32.0 bits (71), Expect = 0.44
Identities = 22/75 (29%), Positives = 30/75 (40%), Gaps = 11/75 (14%)
Query: 91 CRNGGTCVLGSFCVCPAHFTGRYC--EHDQRRSECGALEHG--------AWTLRACHLCR 140
C+NG C C +C E D R S ++G W ++ C CR
Sbjct: 664 CQNGFVMCRRMVCDCENPTVDLFCCPECDPRLSSQCLHQNGETLYNSGDTW-VQNCQQCR 722
Query: 141 CIFGALHCLPLQTPD 155
C+ G + C PL PD
Sbjct: 723 CLQGEVDCWPLPCPD 737
>gi|223029472 NEL-like protein 2 isoform b precursor [Homo sapiens]
Length = 816
Score = 43.9 bits (102), Expect = 1e-04
Identities = 18/40 (45%), Positives = 22/40 (55%), Gaps = 3/40 (7%)
Query: 81 GEGASARPRC---CRNGGTCVLGSFCVCPAHFTGRYCEHD 117
G G + + C CRNGG C+ + C CP FTG CE D
Sbjct: 516 GNGTTCKAFCKDGCRNGGACIAANVCACPQGFTGPSCETD 555
Score = 32.0 bits (71), Expect = 0.44
Identities = 22/75 (29%), Positives = 30/75 (40%), Gaps = 11/75 (14%)
Query: 91 CRNGGTCVLGSFCVCPAHFTGRYC--EHDQRRSECGALEHG--------AWTLRACHLCR 140
C+NG C C +C E D R S ++G W ++ C CR
Sbjct: 665 CQNGFVMCRRMVCDCENPTVDLFCCPECDPRLSSQCLHQNGETLYNSGDTW-VQNCQQCR 723
Query: 141 CIFGALHCLPLQTPD 155
C+ G + C PL PD
Sbjct: 724 CLQGEVDCWPLPCPD 738
>gi|223029470 NEL-like protein 2 isoform a [Homo sapiens]
Length = 866
Score = 43.9 bits (102), Expect = 1e-04
Identities = 18/40 (45%), Positives = 22/40 (55%), Gaps = 3/40 (7%)
Query: 81 GEGASARPRC---CRNGGTCVLGSFCVCPAHFTGRYCEHD 117
G G + + C CRNGG C+ + C CP FTG CE D
Sbjct: 566 GNGTTCKAFCKDGCRNGGACIAANVCACPQGFTGPSCETD 605
Score = 32.0 bits (71), Expect = 0.44
Identities = 22/75 (29%), Positives = 30/75 (40%), Gaps = 11/75 (14%)
Query: 91 CRNGGTCVLGSFCVCPAHFTGRYC--EHDQRRSECGALEHG--------AWTLRACHLCR 140
C+NG C C +C E D R S ++G W ++ C CR
Sbjct: 715 CQNGFVMCRRMVCDCENPTVDLFCCPECDPRLSSQCLHQNGETLYNSGDTW-VQNCQQCR 773
Query: 141 CIFGALHCLPLQTPD 155
C+ G + C PL PD
Sbjct: 774 CLQGEVDCWPLPCPD 788
>gi|5453766 NEL-like protein 2 isoform b precursor [Homo sapiens]
Length = 816
Score = 43.9 bits (102), Expect = 1e-04
Identities = 18/40 (45%), Positives = 22/40 (55%), Gaps = 3/40 (7%)
Query: 81 GEGASARPRC---CRNGGTCVLGSFCVCPAHFTGRYCEHD 117
G G + + C CRNGG C+ + C CP FTG CE D
Sbjct: 516 GNGTTCKAFCKDGCRNGGACIAANVCACPQGFTGPSCETD 555
Score = 32.0 bits (71), Expect = 0.44
Identities = 22/75 (29%), Positives = 30/75 (40%), Gaps = 11/75 (14%)
Query: 91 CRNGGTCVLGSFCVCPAHFTGRYC--EHDQRRSECGALEHG--------AWTLRACHLCR 140
C+NG C C +C E D R S ++G W ++ C CR
Sbjct: 665 CQNGFVMCRRMVCDCENPTVDLFCCPECDPRLSSQCLHQNGETLYNSGDTW-VQNCQQCR 723
Query: 141 CIFGALHCLPLQTPD 155
C+ G + C PL PD
Sbjct: 724 CLQGEVDCWPLPCPD 738
>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
Length = 1541
Score = 42.7 bits (99), Expect = 2e-04
Identities = 28/92 (30%), Positives = 38/92 (41%), Gaps = 4/92 (4%)
Query: 79 AFGEGASARPRCCRNGGTCVLG-SFCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACH 137
+FG S CRNGGTC+LG C CP +TG C G + + +
Sbjct: 515 SFGHDCSLTCDDCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGG 574
Query: 138 LCRCIFGALHCLPLQTPDRCD---PKDFLASH 166
C + GA C P + C+ PK + H
Sbjct: 575 TCDSVTGACRCPPGVSGTNCEDGCPKGYYGKH 606
Score = 38.1 bits (87), Expect = 0.006
Identities = 20/55 (36%), Positives = 27/55 (49%), Gaps = 4/55 (7%)
Query: 91 CRNGGTCVLGSF--CVCPAHFTGRYCEH--DQRRSECGALEHGAWTLRACHLCRC 141
C +GG CV GS C CP F G C++ D+ R+ G +H +LC C
Sbjct: 133 CFHGGRCVPGSAQPCHCPPGFQGPRCQYDVDECRTHNGGCQHRCVNTPGSYLCEC 187
Score = 37.4 bits (85), Expect = 0.010
Identities = 27/71 (38%), Positives = 31/71 (43%), Gaps = 12/71 (16%)
Query: 91 CRNGGTC-VLGSFCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACHL-CRCIFGALHC 148
CRNGG C C C +TGR+CE C +GA ACHL C C + C
Sbjct: 1307 CRNGGLCHASNGSCSCGLGWTGRHCE-----LACPPGRYGA----ACHLECSCHNNST-C 1356
Query: 149 LPLQTPDRCDP 159
P RC P
Sbjct: 1357 EPATGTCRCGP 1367
Score = 36.2 bits (82), Expect = 0.023
Identities = 32/96 (33%), Positives = 41/96 (42%), Gaps = 16/96 (16%)
Query: 67 GWGPEEPLPYSWAFGEGASARPRC-CRNGGTC-VLGSFCVCPAHFTGRYCEHDQRRSECG 124
G E P P + GA + C C++G C + C+CPA F G +CE R E G
Sbjct: 1371 GQACEHPCPPGF---HGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCE---RGCEPG 1424
Query: 125 ALEHGAWTLRACH-LCRCIFGALHCLPLQTPDRCDP 159
+ G CH C C GA C P+ C P
Sbjct: 1425 SFGEG------CHQRCDCDGGA-PCDPVTGLCLCPP 1453
Score = 35.8 bits (81), Expect = 0.030
Identities = 26/109 (23%), Positives = 39/109 (35%), Gaps = 2/109 (1%)
Query: 80 FGEGASARPRCCRNGGTCVLGSFCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACHLC 139
FG G R +C + C CPA + G +CEH G A A C
Sbjct: 909 FGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAAC 968
Query: 140 RCIFGALHCLPLQTPDRCDPKDFLASHAHGPSAGGAPSLLLLLPCALLH 188
+ G+ C + RC + +H +G + A + C +H
Sbjct: 969 DAVNGSCLCPAGRRGPRC--AETCPAHTYGHNCSQACACFNGASCDPVH 1015
Score = 33.5 bits (75), Expect = 0.15
Identities = 30/96 (31%), Positives = 36/96 (37%), Gaps = 4/96 (4%)
Query: 65 AEGWGPEEPLPYSWAFGEGASARPRC-CRNGGTC-VLGSFCVCPAHFTGRYCEHD-QRRS 121
A GW L A G + R C C+NGGTC + C CP + G CE + R
Sbjct: 1021 APGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEKECLPRD 1080
Query: 122 ECGALEHGAWTLRACHLCRCIFGALHCLPLQTPDRC 157
H L LC G C T D+C
Sbjct: 1081 VRAGCRHSGGCLNG-GLCDPHTGRCLCPAGWTGDKC 1115
Score = 32.7 bits (73), Expect = 0.26
Identities = 26/99 (26%), Positives = 35/99 (35%), Gaps = 18/99 (18%)
Query: 75 PYSWAFGEGASARPRC--------CRNGGTCVLGSFC-------VCPAHFTGRYCEHDQR 119
P WA G + C CR+ G C+ G C +CPA +TG C+
Sbjct: 1064 PEGWA---GLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCL 1120
Query: 120 RSECGALEHGAWTLRACHLCRCIFGALHCLPLQTPDRCD 158
R G + C + GA C P T C+
Sbjct: 1121 RGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCE 1159
Score = 30.8 bits (68), Expect = 0.97
Identities = 33/100 (33%), Positives = 37/100 (37%), Gaps = 22/100 (22%)
Query: 83 GASARPRCCRNGGTC--VLGSFCVCPAHFTGRYCEHDQRRSECGALEHGAWTL------R 134
G + C G C V G C CP TG CE D G W L
Sbjct: 737 GVNCSSSCSCGGAPCHGVTGQ-CRCPPGRTGEDCEAD--------CPEGRWGLGCQEICP 787
Query: 135 AC-HLCRC--IFGALHCLPLQTPDRCDPKDFLASHAHGPS 171
AC H RC GA CLP RC +D + +GPS
Sbjct: 788 ACQHAARCDPETGACLCLPGFVGSRC--QDVCPAGWYGPS 825
Score = 30.8 bits (68), Expect = 0.97
Identities = 23/80 (28%), Positives = 30/80 (37%), Gaps = 13/80 (16%)
Query: 71 EEPLPYSWAFGEGASARPRC-CRNGGTCVLGS-FCVCPAHFTGRYCEHDQRRSECGALEH 128
++ P W G S + RC C N G C + C C +TG C+ A +
Sbjct: 814 QDVCPAGWY---GPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQR--------ACDT 862
Query: 129 GAWTLRACHLCRCIFGALHC 148
G W H C C G C
Sbjct: 863 GHWGPDCSHPCNCSAGHGSC 882
Score = 30.4 bits (67), Expect = 1.3
Identities = 20/61 (32%), Positives = 24/61 (39%), Gaps = 5/61 (8%)
Query: 78 WAFGEGASARPRCCR-NGGTC-VLGSFCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRA 135
WAFG G S +C + + +C C C A F G C Q E G G W
Sbjct: 644 WAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERC---QAECELGYFGPGCWQACT 700
Query: 136 C 136
C
Sbjct: 701 C 701
Score = 30.4 bits (67), Expect = 1.3
Identities = 33/97 (34%), Positives = 37/97 (38%), Gaps = 17/97 (17%)
Query: 83 GASARPRC-CRNGGTCVLGS-FCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACH-LC 139
GA+ C C N TC + C C F G+ CEH C HGA C LC
Sbjct: 1341 GAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEH-----PCPPGFHGA----GCQGLC 1391
Query: 140 RCIFGALHCLPLQTPDRCDPKDFLASHAHGPSAGGAP 176
C GA C P+ C P F H H G P
Sbjct: 1392 WCQHGA-PCDPISGRCLC-PAGF---HGHFCERGCEP 1423
Score = 30.4 bits (67), Expect = 1.3
Identities = 24/80 (30%), Positives = 31/80 (38%), Gaps = 11/80 (13%)
Query: 79 AFGEGASARPRCCRNGGTCVLGSFCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACHL 138
+FGEG R C + C+CP +G C D RR + G +C L
Sbjct: 1425 SFGEGCHQRCDCDGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFGP---------SCTL 1475
Query: 139 -CRCIFGALHCLPLQTPDRC 157
C C GA C P+ C
Sbjct: 1476 HCDCGGGA-DCDPVSGQCHC 1494
Score = 29.3 bits (64), Expect = 2.8
Identities = 21/70 (30%), Positives = 26/70 (37%), Gaps = 10/70 (14%)
Query: 91 CRNGGTCVLGS-FCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACHLCRCIFGALHCL 149
C NGG+C + C CP F G C G + H+C C GA C
Sbjct: 1221 CLNGGSCDAATGACRCPTGFLGTDCNL--------TCPQGRFGPNCTHVCGCGQGAA-CD 1271
Query: 150 PLQTPDRCDP 159
P+ C P
Sbjct: 1272 PVTGTCLCPP 1281
Score = 28.1 bits (61), Expect = 6.3
Identities = 19/76 (25%), Positives = 28/76 (36%), Gaps = 14/76 (18%)
Query: 80 FGEGASARPRCCRNGGTC-VLGSFCVCPAHFTGRYCEHD----------QRRSECGALEH 128
+G S C G+C + C+C A + G CE ++R +C +H
Sbjct: 865 WGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQC---QH 921
Query: 129 GAWTLRACHLCRCIFG 144
GA C C G
Sbjct: 922 GAACDHVSGACTCPAG 937
>gi|110347437 latent transforming growth factor beta binding protein
4 isoform c [Homo sapiens]
Length = 1557
Score = 42.4 bits (98), Expect = 3e-04
Identities = 25/67 (37%), Positives = 31/67 (46%), Gaps = 11/67 (16%)
Query: 49 SPLNWTSSHFGEVTGSAEGWGPEEPLPYSWAFGEGASARPRCCRNGGTCVLGSFCVCPAH 108
+P N TS G G+A G GP G A P C NGG CV C+CP
Sbjct: 59 APRNATSVDSGAPGGAAPG-GP----------GFRAFLCPLICHNGGVCVKPDRCLCPPD 107
Query: 109 FTGRYCE 115
F G++C+
Sbjct: 108 FAGKFCQ 114
Score = 30.0 bits (66), Expect = 1.7
Identities = 19/45 (42%), Positives = 23/45 (51%), Gaps = 10/45 (22%)
Query: 83 GASARP--RCCRNGGTC-------VLGSF-CVCPAHFTGRYCEHD 117
GAS + C ++ G C + GSF CVCPA F G CE D
Sbjct: 599 GASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEED 643
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 41.6 bits (96), Expect = 5e-04
Identities = 40/127 (31%), Positives = 49/127 (38%), Gaps = 26/127 (20%)
Query: 85 SARPRCCRNGGTC----VLGSFCVCPAHFTGRYCEHDQ----RRSECGALEHGAWTLR-- 134
+ R R C+NGG C CVCPA FTG CEH Q CG A +
Sbjct: 3847 TCRDRPCQNGGQCHDSESSSYVCVCPAGFTGSRCEHSQALHCHPEACGP---DATCVNRP 3903
Query: 135 --ACHLCRCIFGALHCLPLQTPDRCDPKDFLASHAHGPSAGGAPSLLLLLPCALLHRLLR 192
+ CRC G ++ RC+ + + PS GA S L L H LR
Sbjct: 3904 DGRGYTCRCHLG-------RSGLRCEEGVTVTT----PSLSGAGSYLALPALTNTHHELR 3952
Query: 193 PDAPAHP 199
D P
Sbjct: 3953 LDVEFKP 3959
Score = 38.1 bits (87), Expect = 0.006
Identities = 36/124 (29%), Positives = 49/124 (39%), Gaps = 27/124 (21%)
Query: 49 SPLNWTSSHFGEVTGSAEGWGPEEPLPYSWAFGEG-------ASARPRCCRNGGTCV-LG 100
SP S+HF G G L YS+ +G + + C++G TC+ G
Sbjct: 4064 SPATNMSAHFRGCVGEVSVNGKRLDLTYSFLGSQGIGQCYDSSPCERQPCQHGATCMPAG 4123
Query: 101 SF---CVCPAHFTGRYCEHD----QRRSECGALEHGAWTLRACHLCRCIFGALHCLPLQT 153
+ C+C F G CEH+ Q R C HG C RC+ CLP +
Sbjct: 4124 EYEFQCLCRDGFKGDLCEHEENPCQLREPC---LHGG----TCQGTRCL-----CLPGFS 4171
Query: 154 PDRC 157
RC
Sbjct: 4172 GPRC 4175
>gi|21704279 jagged 2 isoform b precursor [Homo sapiens]
Length = 1200
Score = 41.6 bits (96), Expect = 5e-04
Identities = 25/64 (39%), Positives = 31/64 (48%), Gaps = 16/64 (25%)
Query: 91 CRNGGTC---VLGSFCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACH---LCRCIFG 144
C++GGTC V G CVCP F GR+CE + R EC + CH LC +
Sbjct: 431 CQHGGTCKDLVNGYQCVCPRGFGGRHCELE--RDECAS--------SPCHSGGLCEDLAD 480
Query: 145 ALHC 148
HC
Sbjct: 481 GFHC 484
Score = 34.3 bits (77), Expect = 0.088
Identities = 22/65 (33%), Positives = 28/65 (43%), Gaps = 7/65 (10%)
Query: 91 CRNGGTC---VLGSFCVCPAHFTGRYCEHDQRRSECGALEHGA--WTLRACHLCRC--IF 143
C +GG C G C CP F+G CE D E +GA + L + C C F
Sbjct: 469 CHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDF 528
Query: 144 GALHC 148
G +C
Sbjct: 529 GGKNC 533
Score = 33.9 bits (76), Expect = 0.11
Identities = 18/51 (35%), Positives = 25/51 (49%), Gaps = 5/51 (9%)
Query: 79 AFGEGASARPRCCRNGGTCV---LGSFCVCPAHFTGRYCEHDQRRSECGAL 126
A + +S P C NGGTCV C+C + GR C H+ ++C L
Sbjct: 710 AVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHN--TNDCNPL 758
Score = 32.3 bits (72), Expect = 0.33
Identities = 16/51 (31%), Positives = 22/51 (43%), Gaps = 8/51 (15%)
Query: 91 CRNGGTCVLGS----FCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACH 137
C NGGTC+ C CP ++GR CE + +G +CH
Sbjct: 317 CTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGG----SCH 363
Score = 31.6 bits (70), Expect = 0.57
Identities = 13/28 (46%), Positives = 19/28 (67%), Gaps = 3/28 (10%)
Query: 91 CRNGGTCV--LGSF-CVCPAHFTGRYCE 115
CRNGGTC+ + +F C CP+ + G C+
Sbjct: 607 CRNGGTCIDEVDAFRCFCPSGWEGELCD 634
Score = 30.4 bits (67), Expect = 1.3
Identities = 20/66 (30%), Positives = 25/66 (37%), Gaps = 8/66 (12%)
Query: 91 CRNGGTCV---LGSFCVCPAHFTGRYCEH-----DQRRSECGALEHGAWTLRACHLCRCI 142
C G TCV G C CP G C+ S HG+ + C+ CRC+
Sbjct: 798 CAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRSCWSRGTPFPHGSSWVEDCNSCRCL 857
Query: 143 FGALHC 148
G C
Sbjct: 858 DGRRDC 863
Score = 27.7 bits (60), Expect = 8.2
Identities = 15/41 (36%), Positives = 20/41 (48%), Gaps = 4/41 (9%)
Query: 81 GEGASARPRCCRNGGTCVL---GSF-CVCPAHFTGRYCEHD 117
G +A C G CV G+F C+C + FTG YC +
Sbjct: 558 GMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHEN 598
>gi|21704277 jagged 2 isoform a precursor [Homo sapiens]
Length = 1238
Score = 41.6 bits (96), Expect = 5e-04
Identities = 25/64 (39%), Positives = 31/64 (48%), Gaps = 16/64 (25%)
Query: 91 CRNGGTC---VLGSFCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACH---LCRCIFG 144
C++GGTC V G CVCP F GR+CE + R EC + CH LC +
Sbjct: 469 CQHGGTCKDLVNGYQCVCPRGFGGRHCELE--RDECAS--------SPCHSGGLCEDLAD 518
Query: 145 ALHC 148
HC
Sbjct: 519 GFHC 522
Score = 34.3 bits (77), Expect = 0.088
Identities = 22/65 (33%), Positives = 28/65 (43%), Gaps = 7/65 (10%)
Query: 91 CRNGGTC---VLGSFCVCPAHFTGRYCEHDQRRSECGALEHGA--WTLRACHLCRC--IF 143
C +GG C G C CP F+G CE D E +GA + L + C C F
Sbjct: 507 CHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDF 566
Query: 144 GALHC 148
G +C
Sbjct: 567 GGKNC 571
Score = 33.9 bits (76), Expect = 0.11
Identities = 18/51 (35%), Positives = 25/51 (49%), Gaps = 5/51 (9%)
Query: 79 AFGEGASARPRCCRNGGTCV---LGSFCVCPAHFTGRYCEHDQRRSECGAL 126
A + +S P C NGGTCV C+C + GR C H+ ++C L
Sbjct: 748 AVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHN--TNDCNPL 796
Score = 32.3 bits (72), Expect = 0.33
Identities = 16/51 (31%), Positives = 22/51 (43%), Gaps = 8/51 (15%)
Query: 91 CRNGGTCVLGS----FCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACH 137
C NGGTC+ C CP ++GR CE + +G +CH
Sbjct: 317 CTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGG----SCH 363
Score = 31.6 bits (70), Expect = 0.57
Identities = 13/28 (46%), Positives = 19/28 (67%), Gaps = 3/28 (10%)
Query: 91 CRNGGTCV--LGSF-CVCPAHFTGRYCE 115
CRNGGTC+ + +F C CP+ + G C+
Sbjct: 645 CRNGGTCIDEVDAFRCFCPSGWEGELCD 672
Score = 30.4 bits (67), Expect = 1.3
Identities = 20/66 (30%), Positives = 25/66 (37%), Gaps = 8/66 (12%)
Query: 91 CRNGGTCV---LGSFCVCPAHFTGRYCEH-----DQRRSECGALEHGAWTLRACHLCRCI 142
C G TCV G C CP G C+ S HG+ + C+ CRC+
Sbjct: 836 CAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRSCWSRGTPFPHGSSWVEDCNSCRCL 895
Query: 143 FGALHC 148
G C
Sbjct: 896 DGRRDC 901
Score = 27.7 bits (60), Expect = 8.2
Identities = 15/41 (36%), Positives = 20/41 (48%), Gaps = 4/41 (9%)
Query: 81 GEGASARPRCCRNGGTCVL---GSF-CVCPAHFTGRYCEHD 117
G +A C G CV G+F C+C + FTG YC +
Sbjct: 596 GMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHEN 636
>gi|4885631 tyrosine kinase with immunoglobulin-like and EGF-like
domains 1 [Homo sapiens]
Length = 1138
Score = 41.2 bits (95), Expect = 7e-04
Identities = 19/38 (50%), Positives = 24/38 (63%), Gaps = 1/38 (2%)
Query: 83 GASARPRC-CRNGGTCVLGSFCVCPAHFTGRYCEHDQR 119
GA R +C C+NGGTC S CVCP+ + G +CE R
Sbjct: 312 GADCRLQCQCQNGGTCDRFSGCVCPSGWHGVHCEKSDR 349
Score = 31.2 bits (69), Expect = 0.74
Identities = 17/46 (36%), Positives = 20/46 (43%), Gaps = 1/46 (2%)
Query: 80 FGEGASARPRCCRNGGTCV-LGSFCVCPAHFTGRYCEHDQRRSECG 124
+G G + C +GG C CVCP FTG CE R G
Sbjct: 220 WGPGCTKECPGCLHGGVCHDHDGECVCPPGFTGTRCEQACREGRFG 265
>gi|224451128 eyes shut homolog isoform 1 [Homo sapiens]
Length = 3144
Score = 40.8 bits (94), Expect = 0.001
Identities = 17/35 (48%), Positives = 20/35 (57%), Gaps = 8/35 (22%)
Query: 91 CRNGGTC--------VLGSFCVCPAHFTGRYCEHD 117
C NGGTC ++ C CP HFTGR+CE D
Sbjct: 2108 CHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKD 2142
Score = 33.1 bits (74), Expect = 0.20
Identities = 12/28 (42%), Positives = 18/28 (64%), Gaps = 3/28 (10%)
Query: 91 CRNGGTCVLGS---FCVCPAHFTGRYCE 115
CRN GTC+ + FC CP ++G+ C+
Sbjct: 2344 CRNNGTCISDNENLFCECPRLYSGKLCQ 2371
Score = 32.7 bits (73), Expect = 0.26
Identities = 17/43 (39%), Positives = 24/43 (55%), Gaps = 7/43 (16%)
Query: 91 CRNGGTC----VLGSF-CVCPAHFTGRYCEHDQRRSECGALEH 128
C NGG C + G F C+CP +TG++C QR + C L +
Sbjct: 818 CMNGGLCHESTIPGQFVCLCPPLYTGQFCH--QRYNLCDLLHN 858
Score = 31.2 bits (69), Expect = 0.74
Identities = 13/28 (46%), Positives = 15/28 (53%), Gaps = 3/28 (10%)
Query: 91 CRNGGTC---VLGSFCVCPAHFTGRYCE 115
C N G C G C+CP +TG YCE
Sbjct: 1088 CMNEGFCQKSAHGFTCICPRGYTGAYCE 1115
Score = 31.2 bits (69), Expect = 0.74
Identities = 14/31 (45%), Positives = 15/31 (48%), Gaps = 3/31 (9%)
Query: 88 PRCCRNGGTCVL---GSFCVCPAHFTGRYCE 115
P C G TC+ G C CP TG YCE
Sbjct: 2659 PHHCSRGATCISLPHGYTCFCPLGTTGIYCE 2689
Score = 30.4 bits (67), Expect = 1.3
Identities = 21/71 (29%), Positives = 28/71 (39%), Gaps = 24/71 (33%)
Query: 91 CRNGGTCV---LGSFCVCPAHFTGRYC---------EHD-----QRRSECGALEHGAWTL 133
C NGGTC+ +C C + G +C EHD R + C +L HG
Sbjct: 2619 CGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHG---- 2674
Query: 134 RACHLCRCIFG 144
+ C C G
Sbjct: 2675 ---YTCFCPLG 2682
Score = 30.0 bits (66), Expect = 1.7
Identities = 16/44 (36%), Positives = 20/44 (45%), Gaps = 4/44 (9%)
Query: 91 CRNGGTCVLGSF----CVCPAHFTGRYCEHDQRRSECGALEHGA 130
C NGG CV G C C F+G++CE + HGA
Sbjct: 1131 CLNGGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGA 1174
Score = 29.3 bits (64), Expect = 2.8
Identities = 12/31 (38%), Positives = 15/31 (48%), Gaps = 4/31 (12%)
Query: 91 CRNGGTCVL----GSFCVCPAHFTGRYCEHD 117
CRN TC+ C+C F G+ CE D
Sbjct: 860 CRNNSTCLALVDANQHCICREEFEGKNCEID 890
Score = 29.3 bits (64), Expect = 2.8
Identities = 13/30 (43%), Positives = 17/30 (56%), Gaps = 3/30 (10%)
Query: 91 CRNGGTCVLGS---FCVCPAHFTGRYCEHD 117
C+N GTCV + FC C + G +CE D
Sbjct: 937 CKNNGTCVDLTNRFFCNCEPEYHGPFCELD 966
Score = 28.9 bits (63), Expect = 3.7
Identities = 22/70 (31%), Positives = 27/70 (38%), Gaps = 8/70 (11%)
Query: 53 WTSSHFGEVTGSA----EGWGPEEPLPYSWAFGEGASARPRCCRNGGTCVLGS----FCV 104
W + H G+ E E P YS + AS C NG TCV S C+
Sbjct: 2338 WCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVPKSGTDIVCL 2397
Query: 105 CPAHFTGRYC 114
CP +G C
Sbjct: 2398 CPYGRSGPLC 2407
Score = 27.7 bits (60), Expect = 8.2
Identities = 21/72 (29%), Positives = 27/72 (37%), Gaps = 21/72 (29%)
Query: 91 CRNGGTC-----------------VLGSFCVCPAHFTGRYCEHDQRRSECGALEHGAWTL 133
C+NG TC V G C+C + G CE D A EH + T
Sbjct: 690 CKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNS-TC 748
Query: 134 RACHL---CRCI 142
+ HL C C+
Sbjct: 749 KDLHLSYQCVCL 760
>gi|165932370 FAT tumor suppressor homolog 4 [Homo sapiens]
Length = 4981
Score = 40.8 bits (94), Expect = 0.001
Identities = 25/76 (32%), Positives = 36/76 (47%), Gaps = 10/76 (13%)
Query: 77 SWAFGEGASARPRCCRNGGTC--VLGSF-CVCPAHFTGRYCEHDQRRSECGALEHGAWTL 133
SW + P C +GGTC ++G F C CP FTGR CE D ++GA
Sbjct: 3857 SWCEIDIDECLPSPCHSGGTCHNLVGGFSCSCPDGFTGRACERDINECLQSPCKNGA--- 3913
Query: 134 RACHLCRCIFGALHCL 149
+C+ G+ +C+
Sbjct: 3914 ----ICQNFPGSFNCV 3925
Score = 38.1 bits (87), Expect = 0.006
Identities = 23/65 (35%), Positives = 28/65 (43%), Gaps = 7/65 (10%)
Query: 91 CRNGGTC--VLGSF-CVCPAHFTGRYCEHDQRRSECGALEHGAWTLRA--CHLCRCIFGA 145
C+NG C GSF CVC +TG+ CE EC +G + C C FG
Sbjct: 3909 CKNGAICQNFPGSFNCVCKTGYTGKMCESSVNYCECNPCFNGGSCQSGVDSYYCHCPFGV 3968
Query: 146 L--HC 148
HC
Sbjct: 3969 FGKHC 3973
Score = 30.8 bits (68), Expect = 0.97
Identities = 14/29 (48%), Positives = 16/29 (55%), Gaps = 4/29 (13%)
Query: 91 CRNGGTCVLGSF----CVCPAHFTGRYCE 115
C+NGG+C G C CP TGR CE
Sbjct: 4435 CQNGGSCEPGLHSGFTCSCPDSHTGRTCE 4463
Score = 30.0 bits (66), Expect = 1.7
Identities = 16/37 (43%), Positives = 20/37 (54%), Gaps = 4/37 (10%)
Query: 82 EGASARPRCCRNGGTCV---LGSFCVCPAHFTGRYCE 115
EGA R C ++GGTC+ C C TG+YCE
Sbjct: 4163 EGACTRSPC-QHGGTCMDYWSWQQCHCKEGLTGKYCE 4198
Score = 28.5 bits (62), Expect = 4.8
Identities = 12/28 (42%), Positives = 16/28 (57%), Gaps = 3/28 (10%)
Query: 91 CRNGGTCVLGS---FCVCPAHFTGRYCE 115
C NGG+C G +C CP G++CE
Sbjct: 3947 CFNGGSCQSGVDSYYCHCPFGVFGKHCE 3974
>gi|88702793 slit-like 2 [Homo sapiens]
Length = 673
Score = 40.8 bits (94), Expect = 0.001
Identities = 18/32 (56%), Positives = 20/32 (62%), Gaps = 4/32 (12%)
Query: 88 PRCCRNGGTCVLGS----FCVCPAHFTGRYCE 115
P C NGGTC LG+ C+CP FTG YCE
Sbjct: 411 PSTCLNGGTCHLGTRHHLACLCPEGFTGLYCE 442
>gi|134244285 Notch homolog 3 [Homo sapiens]
Length = 2321
Score = 40.4 bits (93), Expect = 0.001
Identities = 35/106 (33%), Positives = 40/106 (37%), Gaps = 15/106 (14%)
Query: 81 GEGASARPRCCRNGGTCV--LGSF-CVCPAHFTGRYCEHDQRRSECGALEHGAWTLRAC- 136
G + PRC NG TCV +G F C CP +TG CE D GA H A T R C
Sbjct: 1167 GPPLDSGPRCLHNG-TCVDLVGGFRCTCPPGYTGLRCEADINECRSGAC-HAAHT-RDCL 1223
Query: 137 --------HLCRCIFGALHCLPLQTPDRCDPKDFLASHAHGPSAGG 174
LC F C + +P P P GG
Sbjct: 1224 QDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGG 1269
Score = 37.4 bits (85), Expect = 0.010
Identities = 30/89 (33%), Positives = 35/89 (39%), Gaps = 15/89 (16%)
Query: 91 CRNGGTCV---LGSFCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACHLCRCIFGA-- 145
C+ GG CV +CVCP TG +CE + +HG CR G
Sbjct: 1055 CQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGG-------TCRGYMGGYM 1107
Query: 146 LHCLPLQTPDRC-DPKDFLASH--AHGPS 171
CLP D C D D AS HG S
Sbjct: 1108 CECLPGYNGDNCEDDVDECASQPCQHGGS 1136
Score = 37.0 bits (84), Expect = 0.014
Identities = 17/33 (51%), Positives = 22/33 (66%), Gaps = 3/33 (9%)
Query: 88 PRCCRNGGTCVLG--SF-CVCPAHFTGRYCEHD 117
P C NGGTCV G SF C+C +TG +C+H+
Sbjct: 930 PSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHE 962
Score = 36.6 bits (83), Expect = 0.018
Identities = 22/63 (34%), Positives = 27/63 (42%), Gaps = 11/63 (17%)
Query: 91 CRNGGTCVLGSF---CVCPAHFTGRYCEHDQRRSECGALEHGAWTLRAC------HLCRC 141
C NGGTCV G C CP +TG++C D EC + C H C C
Sbjct: 245 CLNGGTCVDGVNTYNCQCPPEWTGQFCTEDV--DECQLQPNACHNGGTCFNTLGGHSCVC 302
Query: 142 IFG 144
+ G
Sbjct: 303 VNG 305
Score = 36.6 bits (83), Expect = 0.018
Identities = 17/30 (56%), Positives = 20/30 (66%), Gaps = 3/30 (10%)
Query: 91 CRNGGTCV--LGSF-CVCPAHFTGRYCEHD 117
CRN TC+ +G F C+C A FTG YCE D
Sbjct: 440 CRNQATCLDRIGQFTCICMAGFTGTYCEVD 469
Score = 36.6 bits (83), Expect = 0.018
Identities = 13/26 (50%), Positives = 20/26 (76%), Gaps = 1/26 (3%)
Query: 91 CRNGGTCV-LGSFCVCPAHFTGRYCE 115
C+NGG CV G++C+CP ++GR C+
Sbjct: 1009 CQNGGRCVQTGAYCLCPPGWSGRLCD 1034
Score = 35.8 bits (81), Expect = 0.030
Identities = 17/29 (58%), Positives = 21/29 (72%), Gaps = 3/29 (10%)
Query: 91 CRNGGTCVL--GSF-CVCPAHFTGRYCEH 116
CR+GGTC+ GSF C CPA +TG CE+
Sbjct: 168 CRHGGTCLNTPGSFRCQCPAGYTGPLCEN 196
Score = 35.4 bits (80), Expect = 0.039
Identities = 24/74 (32%), Positives = 31/74 (41%), Gaps = 5/74 (6%)
Query: 91 CRNGGTC---VLGSFCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRA--CHLCRCIFGA 145
C NGG C V G C CP+ F+G C+ D +GA + + CRC G
Sbjct: 478 CVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGF 537
Query: 146 LHCLPLQTPDRCDP 159
L + D C P
Sbjct: 538 EGTLCDRNVDDCSP 551
Score = 35.0 bits (79), Expect = 0.051
Identities = 22/67 (32%), Positives = 26/67 (38%), Gaps = 13/67 (19%)
Query: 87 RPRCCRNGGTC---VLGSFCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACH------ 137
+P C NGGTC + G CVC +TG C + HGA CH
Sbjct: 281 QPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGA----TCHDRVASF 336
Query: 138 LCRCIFG 144
C C G
Sbjct: 337 YCACPMG 343
Score = 32.3 bits (72), Expect = 0.33
Identities = 17/37 (45%), Positives = 18/37 (48%), Gaps = 7/37 (18%)
Query: 86 ARPRC----CRNGGTCV---LGSFCVCPAHFTGRYCE 115
AR C CR GGTC +G C CP GR CE
Sbjct: 734 ARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCE 770
Score = 29.3 bits (64), Expect = 2.8
Identities = 20/66 (30%), Positives = 24/66 (36%), Gaps = 5/66 (7%)
Query: 91 CRNGGTCVLGS----FCVCPAHFTGRYCEHDQRRSECG-ALEHGAWTLRACHLCRCIFGA 145
C +G C +G C CP + GR C D G HG L RC A
Sbjct: 128 CAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPA 187
Query: 146 LHCLPL 151
+ PL
Sbjct: 188 GYTGPL 193
Score = 29.3 bits (64), Expect = 2.8
Identities = 15/32 (46%), Positives = 16/32 (50%), Gaps = 4/32 (12%)
Query: 88 PRCCRNGGTC----VLGSFCVCPAHFTGRYCE 115
P CRNGGTC L C C F G+ CE
Sbjct: 203 PSPCRNGGTCRQSGDLTYDCACLPGFEGQNCE 234
Score = 28.9 bits (63), Expect = 3.7
Identities = 23/80 (28%), Positives = 32/80 (40%), Gaps = 17/80 (21%)
Query: 86 ARPRCCRN----------GGTCV--LGSF-CVCPAHFTGRYCEHDQRRSECGALEHGAWT 132
A PRC R+ GTC + SF C CP + G +CE D + +G
Sbjct: 880 AGPRCARDVDECLSNPCGPGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTC 939
Query: 133 LRACH----LCRCIFGALHC 148
+ + LCR + HC
Sbjct: 940 VDGVNSFSCLCRPGYTGAHC 959
Score = 27.7 bits (60), Expect = 8.2
Identities = 15/43 (34%), Positives = 18/43 (41%), Gaps = 9/43 (20%)
Query: 101 SFCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRAC-HLCRCI 142
+ C CP FTG C+ D GA C HL RC+
Sbjct: 375 AICTCPPGFTGGACDQDVDECSIGA--------NPCEHLGRCV 409
Score = 27.7 bits (60), Expect = 8.2
Identities = 20/55 (36%), Positives = 22/55 (40%), Gaps = 5/55 (9%)
Query: 95 GTCVLG--SF-CVCPAHFTGRYCEHDQRRSECGALEHGAWTLRAC--HLCRCIFG 144
G CV G SF C C +TG CE HG L +LCRC G
Sbjct: 557 GRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSG 611
>gi|110347412 latent transforming growth factor beta binding protein
4 isoform b [Homo sapiens]
Length = 1587
Score = 40.4 bits (93), Expect = 0.001
Identities = 23/80 (28%), Positives = 30/80 (37%), Gaps = 9/80 (11%)
Query: 45 KHRQSPLNWTSSHFGEVTGSAEGWGPEEP---------LPYSWAFGEGASARPRCCRNGG 95
+ RQ LNW E + P P P G+ P C NGG
Sbjct: 65 RKRQVSLNWQPLTLQEARALLKRRRPRGPGGRGLLRRRPPQRAPAGKAPVLCPLICHNGG 124
Query: 96 TCVLGSFCVCPAHFTGRYCE 115
CV C+CP F G++C+
Sbjct: 125 VCVKPDRCLCPPDFAGKFCQ 144
Score = 30.0 bits (66), Expect = 1.7
Identities = 19/45 (42%), Positives = 23/45 (51%), Gaps = 10/45 (22%)
Query: 83 GASARP--RCCRNGGTC-------VLGSF-CVCPAHFTGRYCEHD 117
GAS + C ++ G C + GSF CVCPA F G CE D
Sbjct: 629 GASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEED 673
>gi|110347431 latent transforming growth factor beta binding protein
4 isoform a [Homo sapiens]
Length = 1624
Score = 40.4 bits (93), Expect = 0.001
Identities = 23/80 (28%), Positives = 30/80 (37%), Gaps = 9/80 (11%)
Query: 45 KHRQSPLNWTSSHFGEVTGSAEGWGPEEP---------LPYSWAFGEGASARPRCCRNGG 95
+ RQ LNW E + P P P G+ P C NGG
Sbjct: 102 RKRQVSLNWQPLTLQEARALLKRRRPRGPGGRGLLRRRPPQRAPAGKAPVLCPLICHNGG 161
Query: 96 TCVLGSFCVCPAHFTGRYCE 115
CV C+CP F G++C+
Sbjct: 162 VCVKPDRCLCPPDFAGKFCQ 181
Score = 30.0 bits (66), Expect = 1.7
Identities = 19/45 (42%), Positives = 23/45 (51%), Gaps = 10/45 (22%)
Query: 83 GASARP--RCCRNGGTC-------VLGSF-CVCPAHFTGRYCEHD 117
GAS + C ++ G C + GSF CVCPA F G CE D
Sbjct: 666 GASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEED 710
>gi|41393583 EGF-like-domain, multiple 7 [Homo sapiens]
Length = 273
Score = 40.0 bits (92), Expect = 0.002
Identities = 32/103 (31%), Positives = 40/103 (38%), Gaps = 16/103 (15%)
Query: 67 GWGPEEPLPYSWAFGEGASARPRCCRNGGTCVLGSFCVCPAHFTGRYCEHDQRRSECGAL 126
GW LP + GA+ CRNGG+CV C CPA + G C+ D EC A
Sbjct: 91 GWKRTSGLPGAC----GAAICQPPCRNGGSCVQPGRCRCPAGWRGDTCQSDV--DECSAR 144
Query: 127 EHG----AWTLRACHLCRCIFG------ALHCLPLQTPDRCDP 159
G + C+C G C+P P R P
Sbjct: 145 RGGCPQRCVNTAGSYWCQCWEGHSLSADGTLCVPKGGPPRVAP 187
>gi|7705889 EGF-like-domain, multiple 7 [Homo sapiens]
Length = 273
Score = 40.0 bits (92), Expect = 0.002
Identities = 32/103 (31%), Positives = 40/103 (38%), Gaps = 16/103 (15%)
Query: 67 GWGPEEPLPYSWAFGEGASARPRCCRNGGTCVLGSFCVCPAHFTGRYCEHDQRRSECGAL 126
GW LP + GA+ CRNGG+CV C CPA + G C+ D EC A
Sbjct: 91 GWKRTSGLPGAC----GAAICQPPCRNGGSCVQPGRCRCPAGWRGDTCQSDV--DECSAR 144
Query: 127 EHG----AWTLRACHLCRCIFG------ALHCLPLQTPDRCDP 159
G + C+C G C+P P R P
Sbjct: 145 RGGCPQRCVNTAGSYWCQCWEGHSLSADGTLCVPKGGPPRVAP 187
>gi|122937283 6720455I24Rik homolog [Homo sapiens]
Length = 1413
Score = 40.0 bits (92), Expect = 0.002
Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 7/80 (8%)
Query: 82 EGASARPRCCRNGGTC--VLGSF-CVCPAHFTGRYCEHDQRRSECGALEHG--AWTLRAC 136
E R CRNGG+C + G++ C CPA F G +CE + + +HG +
Sbjct: 791 ERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGA 850
Query: 137 HLCRC--IFGALHCLPLQTP 154
+LC C F HC + P
Sbjct: 851 YLCVCPESFFGYHCETVSDP 870
Score = 38.1 bits (87), Expect = 0.006
Identities = 35/114 (30%), Positives = 42/114 (36%), Gaps = 10/114 (8%)
Query: 91 CRNGGTCVLG--SF-CVCPAHFTGRYCEHDQRRSECGALEHG--AWTLRACHLCRCIFGA 145
C+NGGTC G SF C CPA F G CE Q + +HG +C C G
Sbjct: 320 CQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGY 379
Query: 146 LHCLPLQTPDRCDPKDFLASHAHGPSAGGAPSLLLLLPCALLHRLLRPDAPAHP 199
D C P L + G L CA + LR + HP
Sbjct: 380 TGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCL-----CAEPFKGLRCETGDHP 428
Score = 37.7 bits (86), Expect = 0.008
Identities = 27/81 (33%), Positives = 32/81 (39%), Gaps = 17/81 (20%)
Query: 91 CRNGGTCVLGS--FCVCPAHFTGRYCEHDQRRSECG----------ALEHGAWTLRACHL 138
CRNGG C+ + C CP F G CE + C +EHG L CH
Sbjct: 474 CRNGGRCLGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHT 533
Query: 139 CRCIFGALHCLPLQTPDRCDP 159
A H LP +P DP
Sbjct: 534 DH---NASHSLP--SPCDSDP 549
Score = 37.4 bits (85), Expect = 0.010
Identities = 16/28 (57%), Positives = 17/28 (60%), Gaps = 3/28 (10%)
Query: 91 CRNGGTCVLGS---FCVCPAHFTGRYCE 115
CRNGGTC C CP FTGR+CE
Sbjct: 589 CRNGGTCKEAGGEYHCSCPYRFTGRHCE 616
Score = 36.2 bits (82), Expect = 0.023
Identities = 20/69 (28%), Positives = 32/69 (46%), Gaps = 7/69 (10%)
Query: 87 RPRCCRNGGTC---VLGSFCVCPAHFTGRYCEHDQRRSECGALEHG--AWTLRACHLCRC 141
R + C +GG+C V G C+C + G +CE ++ +G L ++CRC
Sbjct: 758 RSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRC 817
Query: 142 IFG--ALHC 148
G +HC
Sbjct: 818 PAGFVGVHC 826
Score = 35.0 bits (79), Expect = 0.051
Identities = 15/28 (53%), Positives = 19/28 (67%), Gaps = 3/28 (10%)
Query: 91 CRNGGTCV--LGSF-CVCPAHFTGRYCE 115
C NGGTC +G + C CP F+GR+CE
Sbjct: 628 CHNGGTCFHYIGKYKCDCPPGFSGRHCE 655
Score = 34.7 bits (78), Expect = 0.067
Identities = 31/88 (35%), Positives = 37/88 (42%), Gaps = 21/88 (23%)
Query: 89 RCCRNGGTC----VLGS---FCVCPAHFTGRYCEHDQRRSEC--------GALEHGAWTL 133
R C NGG C V G+ C C + FTGR C D +EC G HG +
Sbjct: 276 RPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDV--NECASQPCQNGGTCTHGINSF 333
Query: 134 RACHLCRCIFGALHCLPLQTPDRCDPKD 161
R C FG C Q+P CD K+
Sbjct: 334 RC--QCPAGFGGPTCETAQSP--CDTKE 357
Score = 33.9 bits (76), Expect = 0.11
Identities = 20/57 (35%), Positives = 24/57 (42%), Gaps = 4/57 (7%)
Query: 91 CRNGGTCV---LGSFCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACHLCRCIFG 144
C NGGTCV G C CP F G C ++ +C G LC+C G
Sbjct: 438 CHNGGTCVDADQGYVCECPEGFMGLDC-RERVPDDCECRNGGRCLGANTTLCQCPLG 493
Score = 32.3 bits (72), Expect = 0.33
Identities = 15/28 (53%), Positives = 17/28 (60%), Gaps = 3/28 (10%)
Query: 91 CRNGGTCVLGS---FCVCPAHFTGRYCE 115
C+NGGTCV G+ C C F GR CE
Sbjct: 1316 CQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
Score = 30.0 bits (66), Expect = 1.7
Identities = 17/40 (42%), Positives = 19/40 (47%), Gaps = 6/40 (15%)
Query: 91 CRNGGTCV---LGSFCVCPAHFTGRYCEHDQRRSECGALE 127
C NGGTC FC C A + GR C Q +CG E
Sbjct: 666 CVNGGTCEDRDTDFFCHCQAGYMGRRC---QAEVDCGPPE 702
Score = 29.3 bits (64), Expect = 2.8
Identities = 24/82 (29%), Positives = 33/82 (40%), Gaps = 12/82 (14%)
Query: 88 PRCCRNGGTCV--LGSF-CVCPAHFTGRYCEHDQRRSECGALEHGAWTLRAC------HL 138
P C NGG+CV +G++ C+C F G CE L C ++
Sbjct: 393 PDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYV 452
Query: 139 CRCI--FGALHCLPLQTPDRCD 158
C C F L C + PD C+
Sbjct: 453 CECPEGFMGLDCRE-RVPDDCE 473
Score = 28.5 bits (62), Expect = 4.8
Identities = 23/75 (30%), Positives = 30/75 (40%), Gaps = 9/75 (12%)
Query: 91 CRNGGTCVLGS---FCVCPAHFTGRYCEHDQ-RRSECGALEHGAWTLRAC--HLCRC--I 142
C NGG+C C CP F G++CE + G +G A + C C
Sbjct: 550 CFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYR 609
Query: 143 FGALHCLPLQTPDRC 157
F HC + PD C
Sbjct: 610 FTGRHC-EIGKPDSC 623
>gi|209571555 von Willebrand factor D and EGF domains [Homo sapiens]
Length = 1590
Score = 39.7 bits (91), Expect = 0.002
Identities = 24/69 (34%), Positives = 32/69 (46%), Gaps = 6/69 (8%)
Query: 91 CRNGGTCVLGSFCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACHLCRCIFGALHCLP 150
C++GGTC+ G+ C CP F G CE C E+G L +C+C G P
Sbjct: 1366 CQHGGTCLAGNLCTCPYGFVGPRCETMVCNRHC---ENGGQCLTP-DICQCKPGWYG--P 1419
Query: 151 LQTPDRCDP 159
+ CDP
Sbjct: 1420 TCSTALCDP 1428
Score = 35.8 bits (81), Expect = 0.030
Identities = 25/87 (28%), Positives = 37/87 (42%), Gaps = 6/87 (6%)
Query: 91 CRNGGTCVLGSFCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACHLCRCIFGALHCLP 150
C NGG+C + C+CP F G +C++ C ++G +R ++C C G +
Sbjct: 1430 CLNGGSCNKPNTCLCPNGFFGEHCQNAFCHPPC---KNGGHCMRN-NVCVCREG--YTGR 1483
Query: 151 LQTPDRCDPKDFLASHAHGPSAGGAPS 177
CDP GPS PS
Sbjct: 1484 RFQKSICDPTCMNGGKCVGPSTCSCPS 1510
Score = 34.3 bits (77), Expect = 0.088
Identities = 17/54 (31%), Positives = 25/54 (46%), Gaps = 4/54 (7%)
Query: 91 CRNGGTCVLGSFCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACHLCRCIFG 144
C+N G C+ + C C G C+ + C +HG T A +LC C +G
Sbjct: 1334 CKNHGKCIKPNICQCLPGHGGATCDEEHCNPPC---QHGG-TCLAGNLCTCPYG 1383
Score = 33.5 bits (75), Expect = 0.15
Identities = 11/25 (44%), Positives = 16/25 (64%)
Query: 91 CRNGGTCVLGSFCVCPAHFTGRYCE 115
C+NGG C+ S C CP+ + G C+
Sbjct: 1526 CKNGGECIAPSICHCPSSWEGVRCQ 1550
Score = 32.7 bits (73), Expect = 0.26
Identities = 12/24 (50%), Positives = 16/24 (66%)
Query: 91 CRNGGTCVLGSFCVCPAHFTGRYC 114
C NGG CV S C CP+ ++G+ C
Sbjct: 1494 CMNGGKCVGPSTCSCPSGWSGKRC 1517
Score = 28.9 bits (63), Expect = 3.7
Identities = 16/45 (35%), Positives = 21/45 (46%), Gaps = 7/45 (15%)
Query: 75 PYSWAFGEGASAR-PRC---CRNGGTCVLGSFCVCPAHFTGRYCE 115
P SW EG + P C C GG C+ + C C ++G CE
Sbjct: 1541 PSSW---EGVRCQIPICNPKCLYGGRCIFPNVCSCRTEYSGVKCE 1582
>gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens]
Length = 4588
Score = 39.7 bits (91), Expect = 0.002
Identities = 24/75 (32%), Positives = 31/75 (41%), Gaps = 14/75 (18%)
Query: 81 GEGASARPRC----CRNGGTC---VLGSFCVCPAHFTGRYCEHDQRRSECGALEHGAWTL 133
G+ P C C+NGGTC + G+ C C + F G C+ D HGA
Sbjct: 4084 GQRCQLSPYCKDEPCKNGGTCFDSLDGAVCQCDSGFRGERCQSDIDECSGNPCLHGA--- 4140
Query: 134 RACHLCRCIFGALHC 148
LC G+ HC
Sbjct: 4141 ----LCENTHGSYHC 4151
Score = 29.3 bits (64), Expect = 2.8
Identities = 12/29 (41%), Positives = 16/29 (55%), Gaps = 4/29 (13%)
Query: 91 CRNGGTC----VLGSFCVCPAHFTGRYCE 115
C+NGG C G +C C A + G +CE
Sbjct: 4022 CQNGGVCNPSPAGGYYCKCSALYIGTHCE 4050
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.139 0.482
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,147,988
Number of Sequences: 37866
Number of extensions: 585622
Number of successful extensions: 2735
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 67
Number of HSP's successfully gapped in prelim test: 108
Number of HSP's that attempted gapping in prelim test: 2097
Number of HSP's gapped (non-prelim): 654
length of query: 223
length of database: 18,247,518
effective HSP length: 98
effective length of query: 125
effective length of database: 14,536,650
effective search space: 1817081250
effective search space used: 1817081250
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.