Guide to the Human Genome
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Search of human proteins with 239753698

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239753698 PREDICTED: hypothetical protein [Homo sapiens]
         (416 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239753698 PREDICTED: hypothetical protein [Homo sapiens]           850   0.0  
gi|239748278 PREDICTED: hypothetical protein [Homo sapiens]           850   0.0  
gi|158854042 hypothetical protein LOC222183 [Homo sapiens]             59   8e-09
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        54   3e-07
gi|163965366 nascent polypeptide-associated complex alpha subuni...    52   1e-06
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         51   2e-06
gi|153251865 hypothetical protein LOC84226 [Homo sapiens]              49   1e-05
gi|239748777 PREDICTED: hypothetical protein [Homo sapiens]            47   4e-05
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]           47   4e-05
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]           47   4e-05
gi|187829730 BCL2 binding component 3 isoform 1 [Homo sapiens]         46   5e-05
gi|221139764 PHD and ring finger domains 1 [Homo sapiens]              46   7e-05
gi|41152076 steroid-sensitive protein 1 [Homo sapiens]                 45   9e-05
gi|41152074 steroid-sensitive protein 1 [Homo sapiens]                 45   9e-05
gi|169167740 PREDICTED: hypothetical protein [Homo sapiens]            45   1e-04
gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens]       45   1e-04
gi|182507165 thymus expressed gene 3-like [Homo sapiens]               45   1e-04
gi|113416994 PREDICTED: hypothetical protein [Homo sapiens]            45   2e-04
gi|113416470 PREDICTED: hypothetical protein [Homo sapiens]            45   2e-04
gi|209862765 RUN and SH3 domain containing 2 [Homo sapiens]            45   2e-04
gi|55741719 RUN and SH3 domain containing 2 [Homo sapiens]             45   2e-04
gi|169214061 PREDICTED: hypothetical protein [Homo sapiens]            44   2e-04
gi|169214437 PREDICTED: hypothetical protein [Homo sapiens]            44   2e-04
gi|169213353 PREDICTED: hypothetical protein [Homo sapiens]            44   2e-04
gi|239742598 PREDICTED: hypothetical protein [Homo sapiens]            44   2e-04
gi|188536004 zinc finger protein 469 [Homo sapiens]                    44   3e-04
gi|78042577 MAP7 domain containing 1 [Homo sapiens]                    44   3e-04
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    44   4e-04
gi|17136078 VGF nerve growth factor inducible precursor [Homo sa...    44   4e-04
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]          43   5e-04

>gi|239753698 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 416

 Score =  850 bits (2195), Expect = 0.0
 Identities = 416/416 (100%), Positives = 416/416 (100%)

Query: 1   MCKKSIKFRKKNKDEKNTSSGLQRQATHRDTPHLVTLGFCGTPGQKHFPKKPPLQSLPAR 60
           MCKKSIKFRKKNKDEKNTSSGLQRQATHRDTPHLVTLGFCGTPGQKHFPKKPPLQSLPAR
Sbjct: 1   MCKKSIKFRKKNKDEKNTSSGLQRQATHRDTPHLVTLGFCGTPGQKHFPKKPPLQSLPAR 60

Query: 61  RRATPRRRARVRVTPPVGRGGLLSSWSRAAPTPRSAAEAPPGSAIPAHLPRSVQRVLGAR 120
           RRATPRRRARVRVTPPVGRGGLLSSWSRAAPTPRSAAEAPPGSAIPAHLPRSVQRVLGAR
Sbjct: 61  RRATPRRRARVRVTPPVGRGGLLSSWSRAAPTPRSAAEAPPGSAIPAHLPRSVQRVLGAR 120

Query: 121 RTEPRSAGERRRALPAAAGRKTKTWQSQNQSPRSARAPHTAGAGPGPGPEPRGRRSHSPL 180
           RTEPRSAGERRRALPAAAGRKTKTWQSQNQSPRSARAPHTAGAGPGPGPEPRGRRSHSPL
Sbjct: 121 RTEPRSAGERRRALPAAAGRKTKTWQSQNQSPRSARAPHTAGAGPGPGPEPRGRRSHSPL 180

Query: 181 GFFSPSVPSRSPLPEREPERTDDRSRVESSARAGDQRRGREPTSRDHRAATRRAAHGPFR 240
           GFFSPSVPSRSPLPEREPERTDDRSRVESSARAGDQRRGREPTSRDHRAATRRAAHGPFR
Sbjct: 181 GFFSPSVPSRSPLPEREPERTDDRSRVESSARAGDQRRGREPTSRDHRAATRRAAHGPFR 240

Query: 241 RRERRKPRPRSESSQLACHLDLCFKWLPVASSRRPVAEAEPGRPEFGSASTRGCEEGRRV 300
           RRERRKPRPRSESSQLACHLDLCFKWLPVASSRRPVAEAEPGRPEFGSASTRGCEEGRRV
Sbjct: 241 RRERRKPRPRSESSQLACHLDLCFKWLPVASSRRPVAEAEPGRPEFGSASTRGCEEGRRV 300

Query: 301 PRGTGSTCLRTDGGSLCSEKTQTPEGGCETERPVSVRLALFICLLPRRLQPLIPAHPVRK 360
           PRGTGSTCLRTDGGSLCSEKTQTPEGGCETERPVSVRLALFICLLPRRLQPLIPAHPVRK
Sbjct: 301 PRGTGSTCLRTDGGSLCSEKTQTPEGGCETERPVSVRLALFICLLPRRLQPLIPAHPVRK 360

Query: 361 QTAASPTATRRGRLPRAGQAGQAAHLRRPTISWALYATLQKGSCEVLAIEAHLLVF 416
           QTAASPTATRRGRLPRAGQAGQAAHLRRPTISWALYATLQKGSCEVLAIEAHLLVF
Sbjct: 361 QTAASPTATRRGRLPRAGQAGQAAHLRRPTISWALYATLQKGSCEVLAIEAHLLVF 416


>gi|239748278 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 416

 Score =  850 bits (2195), Expect = 0.0
 Identities = 416/416 (100%), Positives = 416/416 (100%)

Query: 1   MCKKSIKFRKKNKDEKNTSSGLQRQATHRDTPHLVTLGFCGTPGQKHFPKKPPLQSLPAR 60
           MCKKSIKFRKKNKDEKNTSSGLQRQATHRDTPHLVTLGFCGTPGQKHFPKKPPLQSLPAR
Sbjct: 1   MCKKSIKFRKKNKDEKNTSSGLQRQATHRDTPHLVTLGFCGTPGQKHFPKKPPLQSLPAR 60

Query: 61  RRATPRRRARVRVTPPVGRGGLLSSWSRAAPTPRSAAEAPPGSAIPAHLPRSVQRVLGAR 120
           RRATPRRRARVRVTPPVGRGGLLSSWSRAAPTPRSAAEAPPGSAIPAHLPRSVQRVLGAR
Sbjct: 61  RRATPRRRARVRVTPPVGRGGLLSSWSRAAPTPRSAAEAPPGSAIPAHLPRSVQRVLGAR 120

Query: 121 RTEPRSAGERRRALPAAAGRKTKTWQSQNQSPRSARAPHTAGAGPGPGPEPRGRRSHSPL 180
           RTEPRSAGERRRALPAAAGRKTKTWQSQNQSPRSARAPHTAGAGPGPGPEPRGRRSHSPL
Sbjct: 121 RTEPRSAGERRRALPAAAGRKTKTWQSQNQSPRSARAPHTAGAGPGPGPEPRGRRSHSPL 180

Query: 181 GFFSPSVPSRSPLPEREPERTDDRSRVESSARAGDQRRGREPTSRDHRAATRRAAHGPFR 240
           GFFSPSVPSRSPLPEREPERTDDRSRVESSARAGDQRRGREPTSRDHRAATRRAAHGPFR
Sbjct: 181 GFFSPSVPSRSPLPEREPERTDDRSRVESSARAGDQRRGREPTSRDHRAATRRAAHGPFR 240

Query: 241 RRERRKPRPRSESSQLACHLDLCFKWLPVASSRRPVAEAEPGRPEFGSASTRGCEEGRRV 300
           RRERRKPRPRSESSQLACHLDLCFKWLPVASSRRPVAEAEPGRPEFGSASTRGCEEGRRV
Sbjct: 241 RRERRKPRPRSESSQLACHLDLCFKWLPVASSRRPVAEAEPGRPEFGSASTRGCEEGRRV 300

Query: 301 PRGTGSTCLRTDGGSLCSEKTQTPEGGCETERPVSVRLALFICLLPRRLQPLIPAHPVRK 360
           PRGTGSTCLRTDGGSLCSEKTQTPEGGCETERPVSVRLALFICLLPRRLQPLIPAHPVRK
Sbjct: 301 PRGTGSTCLRTDGGSLCSEKTQTPEGGCETERPVSVRLALFICLLPRRLQPLIPAHPVRK 360

Query: 361 QTAASPTATRRGRLPRAGQAGQAAHLRRPTISWALYATLQKGSCEVLAIEAHLLVF 416
           QTAASPTATRRGRLPRAGQAGQAAHLRRPTISWALYATLQKGSCEVLAIEAHLLVF
Sbjct: 361 QTAASPTATRRGRLPRAGQAGQAAHLRRPTISWALYATLQKGSCEVLAIEAHLLVF 416


>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
          Length = 653

 Score = 58.9 bits (141), Expect = 8e-09
 Identities = 83/312 (26%), Positives = 117/312 (37%), Gaps = 52/312 (16%)

Query: 41  GTPGQKHFPKKPPLQSLPARRRATPRRRARVRVTPPVGRGGLLSSWSRAAPTPRSAAEAP 100
           G PG  H P   P    P  R     + A    TPP  RG       + +P+PRSA    
Sbjct: 326 GRPGSAHSPPDKPSSPSPRVRD----KAAAAAPTPPA-RG-------KESPSPRSA---- 369

Query: 101 PGSAIPAHLPRSVQRVLGARRTEPRSAGERRRALPAAAGRKTKTWQSQNQSPRS------ 154
                P+   R  +   GA R   R    RR    A+A R+    + +   PR       
Sbjct: 370 -----PSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLS 424

Query: 155 -ARAPHTAGAG---PGPGPEPRGRRSHSPLGFFSPSVPSR------SPLPERE-----PE 199
            AR+   +G+G   PGPGPEP   R H   G  +   P R      SP P        PE
Sbjct: 425 RARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPE 484

Query: 200 -RTDDRS-----RVESSARAGDQRRGREPTSRDHRAATRRAAHGPFRRRERRKPRPRSES 253
            ++  RS     R  SS+R+  + R R    R H  +   +   P  R +  + R R   
Sbjct: 485 GKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRARHSE 544

Query: 254 SQLACHLDLCFKWLPVASSRRPVAE-AEPGRPEFGSASTRGCEEGRRVPRGTGSTCLRTD 312
           ++          + P+   RR      EP R    SA  R     R  P  + S+CL +D
Sbjct: 545 AEATRARRRSRSYSPIRKRRRDSPSFMEPRR--ITSARKRPIPYYRPSP-SSSSSCLSSD 601

Query: 313 GGSLCSEKTQTP 324
             +    ++ +P
Sbjct: 602 YSTRSHSRSPSP 613


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 84/336 (25%), Positives = 117/336 (34%), Gaps = 72/336 (21%)

Query: 49  PKKPPLQSLPARRRATPRRRARV------RVTPPVGRGGLLSSWSRAAPTPRSAAEAPPG 102
           P  PP ++ P R R+ P+   ++        +PP  +   +S  + ++P     A AP  
Sbjct: 390 PVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGS 449

Query: 103 SAIPAHLPRSVQRVLGARR-------TEPRSAGERRRALPAAAGRK-----TKTWQSQNQ 150
               +  P S  R  G  +       T  R  G  R    A  GR      TK   S+++
Sbjct: 450 HREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSR 509

Query: 151 SPRSARAPHTAGAGPGPGPEPRGR---------------------------RSHSPLGFF 183
           SP+  R+      G    P+ RGR                           RSHS     
Sbjct: 510 SPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPAT 569

Query: 184 SPSVPSRSPLPE-----REPERTDDRSRVESSARAGDQRRGREPTSRDHRAATRRA-AHG 237
                SR+P        R P R   RSR  +  R+  +   R   SR    A RR+    
Sbjct: 570 RGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRS 629

Query: 238 PFRRRER-RKPRPRSESSQLACHLDLCFKWLPVASSRRPVAEAEPGRPEFGSASTRGCEE 296
           P RRR R R P  RS  S+                SR P   A  GR    + + RG   
Sbjct: 630 PVRRRSRSRSPARRSGRSR----------------SRTP---ARRGRSRSRTPARRGRSR 670

Query: 297 GRRVPRGTGSTCLRTDGGSLCSEKTQTPEGGCETER 332
            R   R +G +  RT      S +++TP  G    R
Sbjct: 671 SRTPARRSGRSRSRTPARRGRS-RSRTPRRGRSRSR 705



 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 58/236 (24%), Positives = 88/236 (37%), Gaps = 32/236 (13%)

Query: 49   PKKPPLQSLPARRRATPRRRARVRVTPPVGRGGLLSS------------WSRAAPTPRSA 96
            PK P  ++LP R R+    + R     P G     SS             SR++P P++ 
Sbjct: 1624 PKAPAPRALPRRSRSGSSSKGRG--PSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTK 1681

Query: 97   AEAPPGSAIPAHLPRSVQRVLGARRTEPRSAGE--------RRRALPAAAGRKTKTWQSQ 148
            +  PP        P   ++   +RR+   S+          R R  P+ +  +       
Sbjct: 1682 SRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRS 1741

Query: 149  NQSPRSARAPHT---AGAGPGPGPEPRG-RRSHSPLGFFSPSVPSR------SPLPEREP 198
            ++  RSA +P T   +  G  P P+PRG +RS S           R      S    R  
Sbjct: 1742 SRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRR 1801

Query: 199  ERTDDRSRVESSARAGDQRRGREPTSRDHRAATRRAAHGPFRRRERRKPRPRSESS 254
            +R+  RSRV    R G     R P  ++    + R   G  R     + R RS +S
Sbjct: 1802 QRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTS 1857



 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 78/327 (23%), Positives = 112/327 (34%), Gaps = 51/327 (15%)

Query: 9   RKKNKDEKNTSSGLQRQATHRDTPHLVTLGFCGTPGQKHFPKKPPLQSLPARRRA---TP 65
           R +N   +  S   +R  +H  +P         TP ++   +       PARRR+   TP
Sbjct: 544 RSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRS----RTPARRRSRSRTP 599

Query: 66  RRRARVRVTPPVGRGGLLSSWSRAAPTPRSAAEAPPGSAIPAHLPRSVQRVLGARRTEPR 125
            RR R R   P  RG    S SR     RS   +P              R     R+  R
Sbjct: 600 TRR-RSRSRTPARRG---RSRSRTPARRRSRTRSPV-------------RRRSRSRSPAR 642

Query: 126 SAGERRRALPAAAGRKTKTWQSQNQSPRSARAPHTAGAGPGPGPEPRGRRSHSPLGFFSP 185
            +G  R   PA  GR      ++    RS      +G      P  RGR           
Sbjct: 643 RSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGR----------- 691

Query: 186 SVPSRSPLPEREPERTDDRSRVESSARAGDQRRGREPTSRDHRAATRRAAHGPFRRRERR 245
              SRS  P R   R+    R   S     QRRGR  +S + +  +R +     +RR R 
Sbjct: 692 ---SRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTS-----QRRSRS 743

Query: 246 KPRPRSESSQLACHLDLCF-----KWLPVASSRRPVAEAEPGRPEFGSASTRGCEEGRRV 300
              P  + S+++            K     S RR ++ + P   +      R    G   
Sbjct: 744 NSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQ 803

Query: 301 PRGTGSTCLRTDGGSLC---SEKTQTP 324
           P+    T  R    S      +K++TP
Sbjct: 804 PKAKSRTPPRRSRSSSSPPPKQKSKTP 830



 Score = 45.4 bits (106), Expect = 9e-05
 Identities = 83/367 (22%), Positives = 127/367 (34%), Gaps = 76/367 (20%)

Query: 85   SWSRAAPTPRSAAEAPPGSAIPAHLPRSVQRVLGARRTEPRSAGERRRALPAAAGRKTKT 144
            S S  +P     A      +I + +  +V R     R+   S+ E +  LP    R++++
Sbjct: 1382 SSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRS 1441

Query: 145  WQSQNQSPRSARAPHTAGAGPGPG------------------PEPRG------RRSHSPL 180
              S      S      + +G  PG                  PEP+        RS SP 
Sbjct: 1442 GSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSP- 1500

Query: 181  GFFSPSVPSRSPLPEREPERTD--------------DRSRVESSAR------AGDQRRGR 220
               SP + ++   P+RE   ++               RSR  SS        A  Q R  
Sbjct: 1501 --SSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSE 1558

Query: 221  EPTSRDHRAATRRAAHGPFRRRERRKPRPRSES-SQLACHLDLCFKWLPVASSRRPVAEA 279
              +S D +A TR     P R+R R    P  +S S+L+           V    R    A
Sbjct: 1559 SDSSPDSKAKTRT----PLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRA 1614

Query: 280  EPGRPEFGSASTRGCEEGRRVPRGTGSTCLRTDGGSLCSEKTQTPEGGCET----ERPVS 335
            + G     S+        R +PR       R+  GS    +  +PEG   T    E P  
Sbjct: 1615 QSGS---DSSPEPKAPAPRALPR-------RSRSGSSSKGRGPSPEGSSSTESSPEHPPK 1664

Query: 336  VRLALFICLLPRRLQPLIPAHPVRKQTAASPTATRRGRLPRAGQAGQAA----------H 385
             R A          +      P R+ + +SP  TR+ RL R  ++  ++          H
Sbjct: 1665 SRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRH 1724

Query: 386  LRRPTIS 392
             R P++S
Sbjct: 1725 RRSPSVS 1731



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 99/379 (26%), Positives = 134/379 (35%), Gaps = 77/379 (20%)

Query: 59   ARRRATP--RRRARVRVTPPVGRGGLLSSWSRAAPTPR-SAAEAPPGSAIPAHLPRSVQR 115
            +R RA+P  RRR+R R TPPV R     S SR   T R S +  PP   +     RS   
Sbjct: 1911 SRSRASPVSRRRSRSR-TPPVTRR---RSRSRTPTTRRRSRSRTPP---VTRRRSRSRTP 1963

Query: 116  VLGARRTEPRSAGERRRALPAAAGRKTKTWQSQNQSP------RSARAPHTAGAGPGPGP 169
             +  RR+  R++   RR   +     T+       SP      RS  +P T        P
Sbjct: 1964 PVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTP 2023

Query: 170  EPRGRRSHSPLGFFSPSVPSRSPLPEREPERTDDRSRVESSARAGDQR--RGREPTSRDH 227
                RRS S           R+PL  R+  R+     +   +R+   R  RG+   +R  
Sbjct: 2024 PAIRRRSRS-----------RTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSP 2072

Query: 228  RAATRRAAHGPF--RRRERRKPRPRSESSQLACHLDLCFKWLPVA--SSRRPVAEAEPGR 283
             A  RR+A G    R R    P  R+ S           +  PVA  SSR         R
Sbjct: 2073 PAIRRRSASGSSSDRSRSATPPATRNHSGS---------RTPPVALNSSRMSCF----SR 2119

Query: 284  PEFGSASTRGCEE-GRRVPRGTGST---CLRTDGGSLCS---------EKTQTPEGGCET 330
            P         C   G   P G+  T    L+  GGS+           ++T  PE   ++
Sbjct: 2120 PSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQS 2179

Query: 331  ERPVSVRLALFICLLPRRLQP-------------LIPAHPVRKQTAASPTATRRGRLPRA 377
                 + LAL    L     P              +PA         +P A    R+P A
Sbjct: 2180 R----IALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAA 2235

Query: 378  GQAG-QAAHLRRPTISWAL 395
              A    A  R P I  A+
Sbjct: 2236 SAAAMNLASARTPAIPTAV 2254



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 48/198 (24%), Positives = 73/198 (36%), Gaps = 34/198 (17%)

Query: 84   SSWSRAAPTPRSAAEAPPGSA---IPAHLPRSVQRVLGARRTEPRSAGERRRALPAAAGR 140
            SS S ++ +  S+    P  A   +P+  P   + V   R  EP  A  +RR+  +++  
Sbjct: 2555 SSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSS 2614

Query: 141  KTKTWQSQNQSPRSARAPHTAG---------------AGPGPG----------PEPRGRR 175
             + +  S + S  S+ +  ++                A PGP           P P  RR
Sbjct: 2615 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERR 2674

Query: 176  SHSPLGFFSPSVPSRS----PLPEREPERTDDRSRVESSARAGDQRRGREPTSR--DHRA 229
            S SP         SRS    P+  R P         +SS+     RRG+   SR   H+ 
Sbjct: 2675 SRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKR 2734

Query: 230  ATRRAAHGPFRRRERRKP 247
                 +  P R R  R P
Sbjct: 2735 RRETPSPRPMRHRSSRSP 2752



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 96/389 (24%), Positives = 135/389 (34%), Gaps = 62/389 (15%)

Query: 15   EKNTSSGLQRQATHRDTPHLVTLGFCGTPGQKHFPKKPPLQSLPARRRATPRRRARVRVT 74
            EK+ SS  +R A+   +P   T       G+   PK   LQ     R  +  RR + R T
Sbjct: 1737 EKSRSSRRRRSAS---SPRTKTTS---RRGRSPSPKPRGLQ-----RSRSRSRREKTRTT 1785

Query: 75   PPVGRGGLLSSWSRAAPTPRSAAEAPP----GSAIPAHLPRSVQRVLGARRTEPRSAGER 130
                R G   S SR     RS +        GS   +  P        AR+   R++  R
Sbjct: 1786 RRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSP--------ARQESSRTSSRR 1837

Query: 131  RRALPAAAGRKTKTWQSQNQSPRSARAPHTAGAGPGPGPEPRGRRSHSPLGFFSPSVPSR 190
            RR       R   T + +++S R++ AP             R  RS +PL     S    
Sbjct: 1838 RRG----RSRTPPTSRKRSRS-RTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRT 1892

Query: 191  SPLPEREPERTDDRSRVESSARAG--DQRRGREPTSRDHRAATRRAAHGPFRRRERRKP- 247
            SP+  R        +R  S +RA    +RR R  T    R  +R       RR   R P 
Sbjct: 1893 SPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPP 1952

Query: 248  --RPRSESSQLACHLDLCFKWLPVASSRRPVAEAEPGRPEFGSASTRGCEEGRRVPRGTG 305
              R RS S              P  + RR  +   P       + +R     RR  R   
Sbjct: 1953 VTRRRSRSR------------TPPVTRRRSRSRTSPITRR--RSRSRTSPVTRRRSRSRT 1998

Query: 306  STCLRTDGGSLCSEKTQTPEGGCETERPVSVRLALFICLLPRRLQPLIPAHPVRKQTAAS 365
            S   R    S  S  T+       +  P ++R         RR +   P  P ++  + S
Sbjct: 1999 SPVTRRRSRSRTSPVTRRRS---RSRTPPAIR---------RRSRSRTPLLPRKRSRSRS 2046

Query: 366  PTATR---RGRLPRAGQAGQAAHLRRPTI 391
            P A R   R R PR  +  ++     P I
Sbjct: 2047 PLAIRRRSRSRTPRTARGKRSLTRSPPAI 2075



 Score = 37.4 bits (85), Expect = 0.025
 Identities = 65/294 (22%), Positives = 93/294 (31%), Gaps = 41/294 (13%)

Query: 43   PGQKHFPKKPPLQSLPARRRATPRRRARVRVTPPVGRGGLLSSWSRAAPT---------- 92
            P Q   P        P     + + R  +  T PV     LSS + A  T          
Sbjct: 2435 PSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGML 2494

Query: 93   -------PRSAAEAPPGS-------AIPAHLPRSVQRVLGARRTEPRSAGERRRALPAAA 138
                   P S    PP S       A+ A  P   +R   +  +   S+     +  +++
Sbjct: 2495 SVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSS 2554

Query: 139  GRKTKTWQSQNQS------------PRSARAPHTA-GAGPGPGPEPRGRRSHSPLGFFSP 185
               + +  S+  S            P    AP  A   G  P P P  R+  S     S 
Sbjct: 2555 SSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSS 2614

Query: 186  SVPSRSPLPEREPERTDDRSRVESSARAGDQRRGREPTSRDHRAATRRAAHGPFRRRERR 245
            S  S S         +   S   SS+ +        P     +A  + A+       ERR
Sbjct: 2615 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERR 2674

Query: 246  KPRPRSESSQLACHLDLCFKWLPVASSRRPVAEAEPGRPEFGSASTRGCEEGRR 299
               PR     L     L +   PV   RRP  +  P R +  S+S RG   G+R
Sbjct: 2675 SRSPRKPIDSLRDSRSLSYS--PV-ERRRPSPQPSP-RDQQSSSSERGSRRGQR 2724



 Score = 35.0 bits (79), Expect = 0.13
 Identities = 59/278 (21%), Positives = 98/278 (35%), Gaps = 55/278 (19%)

Query: 7   KFRKKNKDE-KNTSSGLQRQATHRDTPHLVTLGFCGTPGQKHFPKKPPLQSLPARRRATP 65
           K +KK KD  + + S   R+   + +          +  +KH    P      ++R++  
Sbjct: 188 KKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPK-----SKRKSKD 242

Query: 66  RRRARVRVTPPVGRG---------GLLSSWSRAAPTPRSAAEAPPGSAIPAHLPRSVQRV 116
           ++R R R T P  +             SS   +    RSAA     +A+    P      
Sbjct: 243 KKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGR 302

Query: 117 LG---ARRTEPRSAGERRRALPAAAGRKTKTW-------QSQNQSPRSARAPHTAGAGPG 166
            G   A  +EP +   +R + P  A ++  +        + +  + R + +P  +  GP 
Sbjct: 303 RGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPE 362

Query: 167 P-------------GPEPRGRR--SHSPLGFFSPSVPSRSPLPEREPERTDDRSRVESSA 211
           P              P+P      S  P+   S + P+R   P + PE+    S  ESS 
Sbjct: 363 PPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESS- 421

Query: 212 RAGDQRRGREPTSRDHRAATRRAAHGPFRRRERRKPRP 249
                     P S      +R A+  P    E  KP P
Sbjct: 422 ----------PPSPQPTKVSRHASSSP----ESPKPAP 445



 Score = 34.3 bits (77), Expect = 0.21
 Identities = 46/200 (23%), Positives = 82/200 (41%), Gaps = 32/200 (16%)

Query: 64  TPRRRARVRVTPPVGRGGLLSSWSRAAPTPRSAAEAPPGSAIPAHLPRSVQRVLGARRTE 123
           T +RR+R   +P + +  + S  SR+  +PRS A++            S++R L      
Sbjct: 736 TSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKS----------RLSLRRSLSGSSPC 785

Query: 124 PRSAGERRRALPAAAGRKTKTWQSQNQSPRSARAPHTAGAGPGPGPEPR----GRRSHSP 179
           P+   +          R++++  SQ ++ +S   P  + +   P P+ +     R+SHS 
Sbjct: 786 PKQKSQ-------TPPRRSRSGSSQPKA-KSRTPPRRSRSSSSPPPKQKSKTPSRQSHSS 837

Query: 180 LGFFSPSVPSRSPLPEREPERTDDRSRVESSARAGDQRRGREPTSRD----HRAATRRAA 235
               SP    +S  P R+   T  ++  +S      QRR    +S D     R  +R + 
Sbjct: 838 ---SSPHPKVKSGTPPRQGSITSPQANEQS---VTPQRRSCFESSPDPELKSRTPSRHSC 891

Query: 236 HGPFRRRERRKPRPRSESSQ 255
            G    R +    PR   S+
Sbjct: 892 SGSSPPRVKSSTPPRQSPSR 911



 Score = 31.6 bits (70), Expect = 1.4
 Identities = 27/99 (27%), Positives = 44/99 (44%), Gaps = 21/99 (21%)

Query: 167 PGPEPRGRRSHSPLGFFSPSVPSRSPLPE--REPERTDDRSRVESSARAGDQRRG----- 219
           P PEP       P      S  SRSP P+  ++ ++ D   R ESS+   ++++      
Sbjct: 163 PAPEPP-----KPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKK 217

Query: 220 ----REPTSRDHRAATRRAAHGPFRRRERRKPRPRSESS 254
                E   R HR+ T ++     +R+ + K R RS S+
Sbjct: 218 HRSESESKKRKHRSPTPKS-----KRKSKDKKRKRSRST 251


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 82/351 (23%), Positives = 119/351 (33%), Gaps = 40/351 (11%)

Query: 42   TPGQKHFPKKPPLQSLPARRR--ATPRRRARVR---VTPPVGRGGLLSSWSRAAPTPRSA 96
            TP  K  P  PP  + P+ +   ATP  +       VTPP  +GG  +S  + APTP +A
Sbjct: 1257 TPPPKGAPT-PPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAA 1315

Query: 97   AEAPPGSAIPAHLPRSVQRVLGARRTEPRSAGERRRALPAAAGRKTKTWQSQNQSPRSAR 156
                P  +     P+            P+         P++ G  T     +  +P +A 
Sbjct: 1316 TPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAAT 1375

Query: 157  APHTAGAGPGPGPEPRGRRSHSPLGFFSPSVPSRSPL-PEREPERTDDRSRVESSARAGD 215
              H  G    P    RG    SP G   P+ P+  PL P++ P     R    + ++   
Sbjct: 1376 PSHKGGPAMTPPSPKRGPAIPSPKG--DPTSPAVIPLSPKKAPATPVTREGAATPSKGDL 1433

Query: 216  QRRGREPTSRDHRAATRRAAHGPFRRRERRKPRPRSESSQLACHLDLCFKWLPVASSRRP 275
                  P S     AT     GP          P S+               P   +  P
Sbjct: 1434 TPPAVTPVSLKKAPATSAPKGGP--------ATPSSKGD-------------PTLPAVTP 1472

Query: 276  VAEAEPGRPEFGSASTRGCEEGRRVPRGTGSTCLRTDGGSLCSEKTQTPEGGCETERPVS 335
             +  EP  P+   A++   ++    P   G+  L     S   E   TP        P++
Sbjct: 1473 PSPKEPPAPK-QVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPS---SRRDPIA 1528

Query: 336  VRLALFICLLPRRLQP---LIP---AHPVRKQTAASPTATRRGRLPRAGQA 380
                L     P  L P   LIP     P  K+T A PT       P + +A
Sbjct: 1529 PTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEA 1579



 Score = 45.8 bits (107), Expect = 7e-05
 Identities = 50/189 (26%), Positives = 69/189 (36%), Gaps = 25/189 (13%)

Query: 31   TPHLVTLGFC----GTPGQKHFPKKPPLQSLPARRRATPRRR------------ARVRVT 74
            TP +V L F      TP  K  P      S P + RATP  +                 T
Sbjct: 887  TPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAAT 946

Query: 75   PPVGRGGLLSSWSRAAPTPRSAAEAPPGSAIPAHLPRSVQRVLGARRTEPRSAGERRRAL 134
            PP  +GG  +   + APTP +A    P        P+       A    P+       A 
Sbjct: 947  PPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGG----PAT 1002

Query: 135  PAAAGRKTK---TWQSQNQSPRSARAPHTAGAGP-GPGPEPRGRRSHSPLGFFSPSVPSR 190
            P+  G  T    T  S   SP +   P  A   P    P P+G  + +PL   +P+ P+ 
Sbjct: 1003 PSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAA 1062

Query: 191  S-PLPEREP 198
            + P P+  P
Sbjct: 1063 TLPSPKGGP 1071



 Score = 37.4 bits (85), Expect = 0.025
 Identities = 41/159 (25%), Positives = 62/159 (38%), Gaps = 14/159 (8%)

Query: 42   TPGQKHFPKKPPLQSLPARRR--ATPRRRARVR---VTPPVGRGGLLSSWSRAAPTPRSA 96
            TP  K  P  PP  + P+ +   ATP  +        TPP  +GGL +   + APT  +A
Sbjct: 1073 TPSLKGAPT-PPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAA 1131

Query: 97   AEAPPGSAIPAHLPRSVQRVLGARRTEPRS--AGERRRALPAAAGRKTKTWQSQNQSPRS 154
                P   +    P+       A    P+   A    +  P        + +    +P  
Sbjct: 1132 TPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSP 1191

Query: 155  ARAPHTAGAGPGPGPEPR-GRRSHSPLGFFSPSVPSRSP 192
              AP T  A P   P P+ G  + SP G  +P+ P+ +P
Sbjct: 1192 KGAPTTPAATP---PSPKGGLATPSPKG--APTTPAATP 1225



 Score = 35.4 bits (80), Expect = 0.096
 Identities = 49/224 (21%), Positives = 71/224 (31%), Gaps = 16/224 (7%)

Query: 42   TPGQKHFPKKPPLQSLPARRRATPRRR-------------ARVRVTPPVGRGGLLSSWSR 88
            TP  K  P  P  +  P    ATP                     TPP  +GG  +   +
Sbjct: 924  TPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPK 983

Query: 89   AAPTPRSAAEAPPGSAIPAHLPRSVQRVLGARRTEPRSAGERRRALPAAAGRKTKTWQSQ 148
             APTP +A    P        P+            P+ +         A+     T  S 
Sbjct: 984  GAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSP 1043

Query: 149  NQSPRSARAPHTAGAGPGPG-PEPRGRRSHSPLGFFSPSVPSRS-PLPEREPERTDDRSR 206
              SP +   P  A   P    P P+G  + +P    +P+ P+ + P P+  P     +  
Sbjct: 1044 KGSPAATPLPKGAPTTPAATLPSPKGGPA-TPSLKGAPTPPAATPPSPKGGPATPSPKGA 1102

Query: 207  VESSARAGDQRRGREPTSRDHRAATRRAAHGPFRRRERRKPRPR 250
                A      +G   T     A T  AA  P  +     P P+
Sbjct: 1103 PMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPK 1146



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 37/139 (26%), Positives = 48/139 (34%), Gaps = 10/139 (7%)

Query: 38   GFCGTPGQKHFPKKPPLQS-LPARRRATPRRRARVRV---TPPVGRGGLLSSWSRAAPTP 93
            G   TP  K  P  P      P    ATP  +        TPP  +GGL +   + APT 
Sbjct: 1138 GGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTT 1197

Query: 94   RSAAEAPPGSAIPAHLPRSVQRVLGARRTEPRSAGERRRALPAAAGRKTKTWQSQNQSPR 153
             +A    P   +    P+       A    P+       A P+  G  T T  +   SP+
Sbjct: 1198 PAATPPSPKGGLATPSPKGAPTTPAATPPSPKGG----LATPSPKGAPT-TPAATPPSPK 1252

Query: 154  SARA-PHTAGAGPGPGPEP 171
               A P   GA   P   P
Sbjct: 1253 GGPATPPPKGAPTPPAATP 1271



 Score = 29.3 bits (64), Expect = 6.9
 Identities = 31/113 (27%), Positives = 42/113 (37%), Gaps = 10/113 (8%)

Query: 90  APTPRSAAEAPPGSAIPAHLPRSVQRVLGARRTEPRSAGE---RRRALPAAAGRKTKTWQ 146
           +PTP S   AP  SA+    P+ V   L  + T   S       +      A ++     
Sbjct: 855 SPTPPSPKGAPTPSAVTPLSPKGV--TLPPKETPTPSVVNLPFPKEGPATPAPKQAPALS 912

Query: 147 SQNQSPRSAR---APHTAGAGPGP--GPEPRGRRSHSPLGFFSPSVPSRSPLP 194
             + SP+ AR   AP    A P P   P P      SP G  +   P  +P P
Sbjct: 913 MTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTP 965


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 48/166 (28%), Positives = 67/166 (40%), Gaps = 37/166 (22%)

Query: 114 QRVLGARRTEPRSAGERRRALPAAAGRKTKTWQSQNQSPRSARAPHTAGAGPGPGPEPRG 173
           +R    RR + RS   RRR+ P    RK    +S ++SPR      T    P P PE + 
Sbjct: 167 ERSRSPRRRKSRSPSPRRRSSPVRRERK----RSHSRSPRH----RTKSRSPSPAPEKKE 218

Query: 174 RRSHSP---LGFFSPSV------------PSRSPLPE-------------REPERTDDRS 205
           +    P   +    PSV            P   P+PE             +E E+T  RS
Sbjct: 219 KTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRS 278

Query: 206 RVESSARAGDQRRGREPTSRDHRAATRRAAHGPFRR-RERRKPRPR 250
           R  S +R+  + R    T    R  +R  ++ P RR   RR+P PR
Sbjct: 279 RSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPR 324



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 66/256 (25%), Positives = 93/256 (36%), Gaps = 32/256 (12%)

Query: 7   KFRKKNKDEKNTSSGLQRQATHRDTPHLVTLGFCGTPGQKHFPKKPPLQSLPARRRAT-P 65
           ++R++N+   + S         R     V  G  G   ++H P +    S   R++ T P
Sbjct: 484 QYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRR-RRHSPSRSASPSPRKRQKETSP 542

Query: 66  RRRARVRVTPPVGRGGLLSSWSRAAPTPRS--AAEAPPGSAIPAHLPRSVQRVLGARRTE 123
           R R R   +PP  R     S    AP PR       PP    P+  PR  +R    RR  
Sbjct: 543 RGRRRRSPSPPPTRRRRSPS---PAPPPRRRRTPTPPPRRRTPSPPPR--RRSPSPRRYS 597

Query: 124 PRSAGERRRALPAAAGRKTKTWQSQNQSPRSARAPHTAGAGPGPGPEPRGRRSHSP--LG 181
           P     +RR  P+   ++           R+A  P        P P P+ R SHSP    
Sbjct: 598 PPI---QRRYSPSPPPKR-----------RTASPPPPPKRRASPSPPPKRRVSHSPPPKQ 643

Query: 182 FFSPSVPSRSPLPEREPERTDDRSRVESSARAGDQRRGREPTSRDHRAAT-------RRA 234
             SP    RSP    +  +    SR    AR+    +   P+ R     T       RR 
Sbjct: 644 RSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRG 703

Query: 235 AHGPFRRRERRKPRPR 250
           A    +RR+   P  R
Sbjct: 704 ASSSPQRRQSPSPSTR 719



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 60/231 (25%), Positives = 82/231 (35%), Gaps = 35/231 (15%)

Query: 49  PKKPPLQ-SLPARRR-------ATPRRRARVR--VTPPVGRGGLLSSWSRAAPTPRSAAE 98
           PKKPP + S P R+        + PRRR R     TPP          +R +PTP+ +  
Sbjct: 371 PKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPK--------TRHSPTPQQSNR 422

Query: 99  APPG--SAIPAHLPRSVQRVLGARRTEPRSAGERRRALPAAAGRKTK--------TWQSQ 148
                 S  P      V +  G  + E  S   + R +  +   + K        + Q +
Sbjct: 423 TRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQR 482

Query: 149 NQSPRSARAPHTAGAGPGPGPEPRGRRSHSPLGFF------SPSVPSRSPLPEREPERTD 202
            Q  R  +   +         + R +RSH   G        SPS  S SP P +  + T 
Sbjct: 483 RQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPS-RSASPSPRKRQKETS 541

Query: 203 DRSRVESSARAGDQRRGREPTSRDHRAATRRAAHGPFRRRERRKPRPRSES 253
            R R   S      RR R P+        R     P RR     PR RS S
Sbjct: 542 PRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPS 592



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 95/418 (22%), Positives = 142/418 (33%), Gaps = 74/418 (17%)

Query: 4   KSIKFRKKNKDEKNTSSGLQRQATHRDTPHLVTLGFCGTPGQKHFPKKPPLQSLPARRRA 63
           K  K ++K +    + S  + +   R   H        +  + + P++ P      RRR 
Sbjct: 266 KKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRP----SPRRRP 321

Query: 64  TPRRRARVRVTPPVGRGGLLSS------WSRAAPTPRSAAEAPPGSAIPAHLP--RSVQR 115
           +PRRR   R  PP  R     S       S A+ +  S++ +   S  P   P  R+   
Sbjct: 322 SPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSP 381

Query: 116 VLGARRTEPRSAGERRR------ALPAAAGRKTKTWQSQNQSPRSARAPHTAGAGPGPGP 169
               RR  P ++  RRR      A P    R + T Q  N++ R +R   + G   G   
Sbjct: 382 PRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRT-RKSRVSVSPGRTSGKVT 440

Query: 170 EPRGRRSHSPLGFFSPSVPSRSPLPEREPERTDDRSRVESSARAGDQRR----------- 218
           + +G          SPS P+  P      E  +D+    ++A +  QRR           
Sbjct: 441 KHKGTEKRE-----SPS-PAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSS 494

Query: 219 --GREPTSRDHRAATRRAAHGPFRRRERRKPRPRSESSQLACHLDLCFKWLPVASSRRPV 276
             G   +S D R       +G   RR R  P  RS S                 S R+  
Sbjct: 495 DSGSSSSSEDERPKRSHVKNGEVGRRRRHSP-SRSAS----------------PSPRKRQ 537

Query: 277 AEAEPGRPEFGSASTRGCEEGRRVPRGTGSTCLRTDGGSLCSEKTQTPEGGCETERPVSV 336
            E  P          RG       P  T      +        +T TP     T  P   
Sbjct: 538 KETSP----------RGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPR 587

Query: 337 RLALFICLLPRRLQPLI-----PAHPVRKQTAASPTATRRGRLPRAGQAGQAAHLRRP 389
           R +      PRR  P I     P+ P +++TA+ P   +R   P      + +H   P
Sbjct: 588 RRS----PSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPP 641



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 63/311 (20%), Positives = 108/311 (34%), Gaps = 90/311 (28%)

Query: 43  PGQKHFPKKPPLQSLPARRRATPRRRARVRVTPPVGRGGLLSSWSRAAPTPRSAAEAPPG 102
           P ++  P  PP +  P+ RR +P  + R   +PP  R     + S   P  R A+ +PP 
Sbjct: 576 PPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKR----RTASPPPPPKRRASPSPPP 631

Query: 103 SAIPAHLPRSVQRV--LGARRTEPRSAGERRRALPAAAGRKTKTWQSQNQ---SPRSARA 157
               +H P   QR   +  RR+   S+  R+ + P+ + R+ ++ Q   +   SPR  RA
Sbjct: 632 KRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRP-RA 690

Query: 158 PHTAGAGP-------------------------------------GPGPEPRGRR----- 175
           P T+ + P                                        P P+  R     
Sbjct: 691 PQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSS 750

Query: 176 ----------------------SHSPLGFFSPSVP---SRSPLPEREPERTDDRSRVESS 210
                                 S SP   +SP+VP   ++SP P   P R  D+      
Sbjct: 751 RSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQE----- 805

Query: 211 ARAGDQRRGREPTSRDHRAATRRAAHGPFRRRERRKPRPRSESSQLACHLDLCFKWLPVA 270
              G  ++ ++   + H+   +   H     ++ +K +  + ++  A             
Sbjct: 806 ---GGGKKKKKKKDKKHKKDKKHKKH-----KKHKKEKAVAAAAAAAVTPAAIAAATTTL 857

Query: 271 SSRRPVAEAEP 281
           +   PVA  EP
Sbjct: 858 AQEEPVAAPEP 868



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 18/63 (28%), Positives = 29/63 (46%), Gaps = 4/63 (6%)

Query: 195 EREPERTDDRSRVESSARAGDQRRGREPTSRDHRAATRRAAHGPFRRRER----RKPRPR 250
           +++ E  D R + E  +    + R R P  R  R+ + R    P RR  +    R PR R
Sbjct: 145 KKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHR 204

Query: 251 SES 253
           ++S
Sbjct: 205 TKS 207


>gi|153251865 hypothetical protein LOC84226 [Homo sapiens]
          Length = 1984

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 76/290 (26%), Positives = 104/290 (35%), Gaps = 37/290 (12%)

Query: 47   HFPKKPPLQSLPARRRATPRRRARVRVTPPVGRGGLLSSWSR-AAPTPRSAAEAPPGSAI 105
            H P +   +    RR  +P  R+      P  R    SS  R  +P+ RS      G + 
Sbjct: 1631 HSPSQRSHRGPSQRRHHSPSERSH---RSPSERSHRSSSERRHRSPSQRSHR----GPSE 1683

Query: 106  PAHLPRSVQRVLGARRTEPRSAGERRRALPAAAGRKTKTWQSQNQSPRSARAPHTAGAGP 165
             +H   S +R     +   R   ERR   P+    ++   +S ++SP S R+ H+     
Sbjct: 1684 RSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRS-HRSP-SERSHHSPSERS 1741

Query: 166  GPGPEPRGRRSHSPLGFFSPSVPS---------RSPLPERE--PERTDDRSRVESSARAG 214
               P  R   S S     SPS  S         RSP   R   P      S  E S  + 
Sbjct: 1742 HHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSP 1801

Query: 215  DQRRGREPTSRD--------HRAATRRAAHGPFRRRERRKPRPRSESSQLACHLDLCFKW 266
             +RR   P  R         HR+ + R +H  F R  RR    RS S     HL    + 
Sbjct: 1802 SERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSHRRISE-RSHSPSEKSHLSPLERS 1860

Query: 267  LPVASSRRPVAEAEPGR-----PEFGSASTRGCEEGRRVPRGTGSTCLRT 311
                S RR    +  G+      E    S  G  +GR   R   S+C RT
Sbjct: 1861 RCSPSERR--GHSSSGKTCHSPSERSHRSPSGMRQGRTSERSHRSSCERT 1908



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 39/135 (28%), Positives = 54/135 (40%), Gaps = 6/135 (4%)

Query: 120  RRTEPRSAGERRRALPAAAGRKTKTWQSQNQSPRSARAPHTAGAGPGPGPEPRGRRSHSP 179
            R   PR   ER R  P+    ++ + +SQ  S    R  H+        P  +   S S 
Sbjct: 1546 RERTPRGPSERTRHNPSWRNHRSPSERSQRSSLE--RRHHSPSQRSHCSPSRKNHSSPSE 1603

Query: 180  LGFFSPSVPSRSPLPEREPERTDDR---SRVESSARAGDQRRGREPTSRDHRAATRRAAH 236
              + SPS  +    PER      +R   S  + S R   QRR   P+ R HR+ + R +H
Sbjct: 1604 RSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSER-SH 1662

Query: 237  GPFRRRERRKPRPRS 251
                 R  R P  RS
Sbjct: 1663 RSSSERRHRSPSQRS 1677



 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 47/155 (30%), Positives = 61/155 (39%), Gaps = 26/155 (16%)

Query: 125  RSAGERRRALPA-----AAGRKT------KTWQSQNQ----SPR-------SARAPHTAG 162
            RS+ ERR   P+     +  RK       ++W+S +Q    SP        S R  H+  
Sbjct: 1575 RSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPS 1634

Query: 163  AGPGPGPEPRGRRSHSPLGFFSPSVPSRSPLPERE---PERTDDRSRVESSARAGDQRRG 219
                 GP  R   S S     SPS  S     ER    P +   R   E S  +  +RR 
Sbjct: 1635 QRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRH 1694

Query: 220  REPTSRDHRAATRRAAHGPFRRRERRKPRPRSESS 254
            R P+ R HR  + R  H P  +R  R P  RS  S
Sbjct: 1695 RSPSQRSHRGPSERRHHSP-SKRSHRSPARRSHRS 1728



 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 64/259 (24%), Positives = 91/259 (35%), Gaps = 19/259 (7%)

Query: 47   HFPKKPPLQSLPARRRATPRRRA------RVRVTPPVGRGGLLSSWSRAAPTPRSAAEAP 100
            H P +    S   +  ++P  R+      R   +PP      LS     +P+ RS     
Sbjct: 1583 HSPSQRSHCSPSRKNHSSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHR--- 1639

Query: 101  PGSAIPAHLPRSVQRVLGARRTEPRSAGERRRALPAAAGRKTKTWQSQ-NQSPRSARAPH 159
             G +   H   S +          RS+ ERR   P+    +  + +S  + S R  R+P 
Sbjct: 1640 -GPSQRRHHSPSERSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSP- 1697

Query: 160  TAGAGPGPGPEPRGRRSHSPLGFFSPSVPSRSPLPEREPERTDDRSRVESSARAGDQRRG 219
            +  +  GP      RR HSP      S   RS    R P      S  E S  +  +RR 
Sbjct: 1698 SQRSHRGPSE----RRHHSPSKRSHRSPARRS---HRSPSERSHHSPSERSHHSPSERRH 1750

Query: 220  REPTSRDHRAATRRAAHGPFRRRERRKPRPRSESSQLACHLDLCFKWLPVASSRRPVAEA 279
              P+ R H + + R+   P  RR R     R  S     H     +     S RR  +  
Sbjct: 1751 HSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPL 1810

Query: 280  EPGRPEFGSASTRGCEEGR 298
            E  R      S R   E R
Sbjct: 1811 ERSRHSLLERSHRSPSERR 1829



 Score = 38.5 bits (88), Expect = 0.011
 Identities = 47/182 (25%), Positives = 66/182 (36%), Gaps = 11/182 (6%)

Query: 126  SAGERRRALPAAAGRKTKTWQSQNQSPRSARAPHTAGAGPGPGPEPRGRRSHSPLGFFSP 185
            S  ERR   P+     + + +S + SP S R+ H+        P  R R S       SP
Sbjct: 1768 SPSERRHRSPSERRHHSPSEKSHH-SP-SERSHHSPSERRRHSPLERSRHSLLERSHRSP 1825

Query: 186  SVPSRSPLPEREPERTDDRSRV--ESSARAGDQRRGREPTSRDHRAATRRAAHGPFRRRE 243
            S        ER   R  +RS    E S  +  +R    P+ R   +++ +  H P  R  
Sbjct: 1826 SERRSHRSFERSHRRISERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSERSH 1885

Query: 244  RRKPRPRSESSQLACHLDLCFKWLPVASSRRPVAEAEPGRPEFGSASTRGCEEGRRVPRG 303
            R     R   +    H   C +      +R   +E  PGRP  G       E  RR P  
Sbjct: 1886 RSPSGMRQGRTSERSHRSSCER------TRHSPSEMRPGRPS-GRNHCSPSERSRRSPLK 1938

Query: 304  TG 305
             G
Sbjct: 1939 EG 1940



 Score = 34.7 bits (78), Expect = 0.16
 Identities = 46/197 (23%), Positives = 71/197 (36%), Gaps = 34/197 (17%)

Query: 88   RAAPTPRSAAEAPPGSAIPAHLPRSVQRVLGARRTEPRSAGERRRALPA-AAGRKTKTWQ 146
            R+A  PR A    P    P  LP+      G    +  S G+  R +   ++ R  K + 
Sbjct: 1436 RSAQQPRRAYSFQPR---PLRLPKPTDSQSGIA-FQTASVGQPLRTVQKDSSSRSKKNFY 1491

Query: 147  SQNQSPRSARAPHTAGAGPGPGPEPRGR---------------------RSHSPLGFFSP 185
                S + ++   T    PG   + RGR                     + H+   F+  
Sbjct: 1492 RNETSSQESKNLST----PGTRVQARGRILPGSPVKRTWHRHLKDKLTHKEHNHPSFYRE 1547

Query: 186  SVP-SRSPLPEREPERTDDRSRVESSARAGDQRRGREPTSRDHRAATRRAAHGPFRRRER 244
              P   S      P   + RS  E S R+  +RR   P+ R H + +R+    P   R  
Sbjct: 1548 RTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSP-SERSW 1606

Query: 245  RKPRPRSESS--QLACH 259
            R P  R+  S  + +CH
Sbjct: 1607 RSPSQRNHCSPPERSCH 1623



 Score = 33.5 bits (75), Expect = 0.37
 Identities = 60/233 (25%), Positives = 80/233 (34%), Gaps = 29/233 (12%)

Query: 47   HFPKKPPLQSLPARRRATPRRRA------RVRVTPPVGRGGLLSSWSRAAPTPRSAAEAP 100
            H P K   +S   R   +P  R+      R   +P   R    S  S  +P+ RS     
Sbjct: 1711 HSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPS 1770

Query: 101  PG-----SAIPAHLPRSVQRVLGARRTEPRSAGERRRALPAAAGRKTKTWQSQNQSPRSA 155
                   S    H P        + R+   S  ERRR  P    R +   +S ++SP   
Sbjct: 1771 ERRHRSPSERRHHSPSEKSHHSPSERSH-HSPSERRRHSPLERSRHSLLERS-HRSPSER 1828

Query: 156  RAPHTAGAGPGPGPEPRGRRSHSPL--GFFSPSVPSRSPLPEREPERTDDR---SRVESS 210
            R+  +         E    RSHSP      SP   SR    ER    +  +   S  E S
Sbjct: 1829 RSHRSFERSHRRISE----RSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSERS 1884

Query: 211  ARAGDQRRGREPTSRDHRAATRRAAHGPFRRRERR-------KPRPRSESSQL 256
             R+    R    + R HR++  R  H P   R  R        P  RS  S L
Sbjct: 1885 HRSPSGMRQGRTSERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSERSRRSPL 1937


>gi|239748777 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 350

 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 59/190 (31%), Positives = 73/190 (38%), Gaps = 40/190 (21%)

Query: 60  RRRATPRRRARVRVTPPVGRGGLLSSW-SRAAPTPRSAAEA---------PPG------- 102
           R +AT    A   V     R  +   W SRA P PRSA+ A         PPG       
Sbjct: 3   REKATEEAAAPPGVAESPARPRVNEQWGSRAHPNPRSASSAAAAASSSFPPPGFIHPPSS 62

Query: 103 --------SAIPAHLPRSVQRVL-GARRTEPRSAGERRRALPAAAGRKTKTWQSQNQSPR 153
                    A PA  PR + RVL GA       AG R RA  AAA  +     +     R
Sbjct: 63  RAAVHSRLRAAPAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGR---R 119

Query: 154 SARAPHTAGAGPGPGPEPRGRRSHSPLGFFSPSVPSRSPLPEREPERTDDRSRVESSARA 213
             R P     GP P  +PR R  H+    +  +VP  +PL  R P  T  R++     R+
Sbjct: 120 WRRRP-----GPSPPLQPRSRHPHTR---YPRAVPEATPL--RPPPGTRPRAKSRPGCRS 169

Query: 214 GD-QRRGREP 222
                R R P
Sbjct: 170 SPFPARSRTP 179



 Score = 39.3 bits (90), Expect = 0.007
 Identities = 55/199 (27%), Positives = 64/199 (32%), Gaps = 15/199 (7%)

Query: 57  LPARRRATPRRRARVRVTPPVGRGGLLSSWSRAAPTPR--SAAEAPPG---SAIPAHLPR 111
           L A   A PR   RV    P   G L  S  RAA        A AP G      P   P 
Sbjct: 70  LRAAPAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRRWRRRPGPSPP 129

Query: 112 SVQRVLGARRTEPRSAGERRRALPAAAGR-KTKTWQSQNQSPRSARAPHTAGAGPGPG-P 169
              R        PR+  E     P    R + K+      SP  AR+     AGP  G P
Sbjct: 130 LQPRSRHPHTRYPRAVPEATPLRPPPGTRPRAKSRPGCRSSPFPARSRTPGEAGPPRGDP 189

Query: 170 EPRGRRSHSPLGFFSPSVPSRSPLPEREPERTDDRSRVESSARAGDQRRGREPTSRDHRA 229
            PR  R            P RSP     P  +       +  RA  +    +P       
Sbjct: 190 RPRAPRPGDH--------PRRSPALRETPSLSPPSPGRRNGKRAAGKGTTPQPQPPPPPC 241

Query: 230 ATRRAAHGPFRRRERRKPR 248
           ATRR      R R+R   R
Sbjct: 242 ATRREEDMALRTRDRTSSR 260


>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
          Length = 2426

 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 49/186 (26%), Positives = 71/186 (38%), Gaps = 18/186 (9%)

Query: 60   RRRATPRRRARVRVTPPVGRGGLLSSWSRAAPTPRSAAEAPPGSAIPAHLPRSVQRVLGA 119
            +R +  R RAR R +          S SR+    RS+      S   +   RSV +    
Sbjct: 1838 KRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSR-----SRSKSRGRRSVSKEKRK 1892

Query: 120  RRTEPRSAGERRRALPAAAGRKTKTWQSQNQSPRSARAPHTAGAGPGPGPEPRGRRSHSP 179
            R  + RS    R+   +++    KT ++++++P      HT          P  RR    
Sbjct: 1893 RSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHT----------PSRRRRSRS 1942

Query: 180  LG---FFSPSVPSRSPLPEREPERTDDRSRVESSARAGDQRRGREPTSRDHRAATRRAAH 236
            +G    FS S   RS  P R       RSR  S       RR R P+ R    + RR + 
Sbjct: 1943 VGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSR 2002

Query: 237  GPFRRR 242
               RRR
Sbjct: 2003 SVVRRR 2008



 Score = 35.0 bits (79), Expect = 0.13
 Identities = 57/265 (21%), Positives = 92/265 (34%), Gaps = 24/265 (9%)

Query: 119  ARRTEPRSAGERRRALPAAAGRKTKTWQSQNQSPRSARAPHTAGAGPGPGPEPRGR---R 175
            +++ + R  GE+ +   ++   ++K  +S     R   +   + A          R   R
Sbjct: 1803 SKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTR 1862

Query: 176  SHSPLGFFSPSVPSRSPLPEREPERTDDRSRVESSARAGDQRRGREPTSRDHRAATRRAA 235
            S S       S  SRS    R     + R R         +R+ +  +SRD+R   R  +
Sbjct: 1863 SRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARS 1922

Query: 236  HGPFRRRERRKPRPRSESSQLACHLDLCFKWLPVASSRRPVAEAEPGRPEFGSASTRGCE 295
              P RR     P  R  S  +       F   P   SR P   +        + S R   
Sbjct: 1923 RTPSRRSRSHTPSRRRRSRSVGRRRS--FSISPSRRSRTPSRRSRTPSRRSRTPSRRSRT 1980

Query: 296  EGRRVPRGTGSTCLRTDGGSLCSEKTQTPEGGCETERPVSVRLALFICLLPRRLQPLIPA 355
              RR          RT      S +++TP       R  SV       + P RL+     
Sbjct: 1981 PSRR---------SRTP-----SRRSRTPS---RRRRSRSVVRRRSFSISPVRLRR--SR 2021

Query: 356  HPVRKQTAASPTATRRGRLPRAGQA 380
             P+R++ + SP   +R R    G++
Sbjct: 2022 TPLRRRFSRSPIRRKRSRSSERGRS 2046


>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
          Length = 2303

 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 49/186 (26%), Positives = 71/186 (38%), Gaps = 18/186 (9%)

Query: 60   RRRATPRRRARVRVTPPVGRGGLLSSWSRAAPTPRSAAEAPPGSAIPAHLPRSVQRVLGA 119
            +R +  R RAR R +          S SR+    RS+      S   +   RSV +    
Sbjct: 1838 KRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSR-----SRSKSRGRRSVSKEKRK 1892

Query: 120  RRTEPRSAGERRRALPAAAGRKTKTWQSQNQSPRSARAPHTAGAGPGPGPEPRGRRSHSP 179
            R  + RS    R+   +++    KT ++++++P      HT          P  RR    
Sbjct: 1893 RSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHT----------PSRRRRSRS 1942

Query: 180  LG---FFSPSVPSRSPLPEREPERTDDRSRVESSARAGDQRRGREPTSRDHRAATRRAAH 236
            +G    FS S   RS  P R       RSR  S       RR R P+ R    + RR + 
Sbjct: 1943 VGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSR 2002

Query: 237  GPFRRR 242
               RRR
Sbjct: 2003 SVVRRR 2008



 Score = 35.0 bits (79), Expect = 0.13
 Identities = 57/265 (21%), Positives = 92/265 (34%), Gaps = 24/265 (9%)

Query: 119  ARRTEPRSAGERRRALPAAAGRKTKTWQSQNQSPRSARAPHTAGAGPGPGPEPRGR---R 175
            +++ + R  GE+ +   ++   ++K  +S     R   +   + A          R   R
Sbjct: 1803 SKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTR 1862

Query: 176  SHSPLGFFSPSVPSRSPLPEREPERTDDRSRVESSARAGDQRRGREPTSRDHRAATRRAA 235
            S S       S  SRS    R     + R R         +R+ +  +SRD+R   R  +
Sbjct: 1863 SRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARS 1922

Query: 236  HGPFRRRERRKPRPRSESSQLACHLDLCFKWLPVASSRRPVAEAEPGRPEFGSASTRGCE 295
              P RR     P  R  S  +       F   P   SR P   +        + S R   
Sbjct: 1923 RTPSRRSRSHTPSRRRRSRSVGRRRS--FSISPSRRSRTPSRRSRTPSRRSRTPSRRSRT 1980

Query: 296  EGRRVPRGTGSTCLRTDGGSLCSEKTQTPEGGCETERPVSVRLALFICLLPRRLQPLIPA 355
              RR          RT      S +++TP       R  SV       + P RL+     
Sbjct: 1981 PSRR---------SRTP-----SRRSRTPS---RRRRSRSVVRRRSFSISPVRLRR--SR 2021

Query: 356  HPVRKQTAASPTATRRGRLPRAGQA 380
             P+R++ + SP   +R R    G++
Sbjct: 2022 TPLRRRFSRSPIRRKRSRSSERGRS 2046


>gi|187829730 BCL2 binding component 3 isoform 1 [Homo sapiens]
          Length = 261

 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 47/153 (30%), Positives = 59/153 (38%), Gaps = 25/153 (16%)

Query: 40  CGTPGQKHFPKKPPLQSLPARRRATPRRRARVRVTPPVGRGGLLSSWSRAAPTPRSAAEA 99
           CG P ++H P+ P  Q   ARR   PRR A +   PP   G +L    RA P  R     
Sbjct: 29  CG-PRERHGPRTPGGQLPGARRGPGPRRPAPLPARPPGALGSVLRP-LRARPGCRPRRPH 86

Query: 100 PPGSAIPAHLPRSVQR---------VLGARRTEPRSAGERRRALPAAAGRKTKTWQSQNQ 150
           P    +P    R  +R           G+ +  PR A  R  AL  A G           
Sbjct: 87  PAARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALAGG----------A 136

Query: 151 SPRSARAPHTAGAG----PGPGPEPRGRRSHSP 179
           +P  ARA    G+G    PG    PRG  +  P
Sbjct: 137 APGVARAQRPGGSGGRSHPGGPGSPRGGGTVGP 169


>gi|221139764 PHD and ring finger domains 1 [Homo sapiens]
          Length = 1648

 Score = 45.8 bits (107), Expect = 7e-05
 Identities = 66/250 (26%), Positives = 98/250 (39%), Gaps = 37/250 (14%)

Query: 51   KPPLQSLPARRRATPRRRARVRVTPPVGRGGLLSSWSRAAPTPRSAAEAPPGSAIPAHLP 110
            +PP +S       + ++  R RV+   GR     S +R+    RS+  A P  ++    P
Sbjct: 987  RPPSRSRSTSSSRSRKKAKRKRVSREHGR---TRSGTRSESRDRSSRSASP--SVGEERP 1041

Query: 111  RSVQRVLGARRTEPRSAGERRRALPAAA------------GRKTKTWQSQNQSPRSARAP 158
            R  +    +RR+    +  R RA    A            G   +T +S++ SP S+   
Sbjct: 1042 RRQRSKAKSRRSSSDRSSSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSSSYE 1101

Query: 159  HTAGAGPGP---GPEPRGRRSHSPLGFFSPSVPSRSPLPEREPERTDDRSRVESSARAGD 215
            H              PRGR   SP          +    ER  ER D +  V +  R   
Sbjct: 1102 HYESRKKKKRRSASRPRGREC-SPTSSLERLCRHKHQR-ERSHERPDRKESV-AWPRDRR 1158

Query: 216  QRRGREPTSRDHRAATRRAAHGPFRRRERRKPRPRSESSQLACHLDLCFKWLPVASSRRP 275
            +RR R P+S +HRA            RE R+PR R +  Q   H     K     +S  P
Sbjct: 1159 KRRSRSPSS-EHRA------------REHRRPRSREKWPQTRSHSPE-RKGAVREASPAP 1204

Query: 276  VAEAEPGRPE 285
            +A+ EPGR +
Sbjct: 1205 LAQGEPGRED 1214



 Score = 37.7 bits (86), Expect = 0.019
 Identities = 44/157 (28%), Positives = 61/157 (38%), Gaps = 26/157 (16%)

Query: 98   EAPPGSAIPAHLPRSVQRVLGARRTEPRSAGERRRALPAAAGRKTKTWQSQNQSPRSARA 157
            EAPP    P  L  +  RV+  R              P +  R T + +S+ ++ R   +
Sbjct: 968  EAPPS---PDVLQAATHRVVELR--------------PPSRSRSTSSSRSRKKAKRKRVS 1010

Query: 158  PHTAGAGPGPGPEPRGRRSHSPLGFFSPSVPSRSPLPEREPERTDDRSRVESSARAGDQR 217
                    G   E R R S S     SPSV    P  +R   ++   S   SS+R   +R
Sbjct: 1011 REHGRTRSGTRSESRDRSSRSA----SPSVGEERPRRQRSKAKSRRSSSDRSSSRERAKR 1066

Query: 218  RGREPTSRDHRAATRRAAHGPFRRRER-RKPRPRSES 253
            +  +  SR+H    RR   G  RR  R R   P S S
Sbjct: 1067 KKAKDKSREH----RRGPWGHSRRTSRSRSGSPGSSS 1099


>gi|41152076 steroid-sensitive protein 1 [Homo sapiens]
          Length = 950

 Score = 45.4 bits (106), Expect = 9e-05
 Identities = 62/223 (27%), Positives = 88/223 (39%), Gaps = 35/223 (15%)

Query: 7   KFRKKNKDEKNTSSGLQRQ--ATHRDTPHLVTLGFCGTPGQKHFPKK---PP-------- 53
           K R+K   +K  +SG++ Q  A   D          G+  +K  P++   PP        
Sbjct: 271 KIRQKGFVQKCKASGVEGQVVAEGNDGGGGAGRPSLGSEKKKEDPRRAQVPPTRESRVKV 330

Query: 54  LQSLPARRRATPRRRARVRVT--PPVGRGGLLSSWSRA---APTPRSAAEAP----PGSA 104
           L+ L A   A P+  +  R T  PP     +  S SRA   A  P +    P    P + 
Sbjct: 331 LRKLAATAPALPQPPSTPRATTLPPAPATTVTRSTSRAVTVAARPMTTTAFPTTQRPWTP 390

Query: 105 IPAHLPRSVQRVLGARRTE------PRSAGERRRALPAAAGRKTKTWQSQ---NQSPRSA 155
            P+H P +   V+ ARR        P S  ++ R  P    R +K    +   N  P + 
Sbjct: 391 SPSHRPPTTTEVITARRPSVSENLYPPSRKDQHRERPQTTRRPSKATSLESFTNAPPTTI 450

Query: 156 RAPHTAGAGPGPGPEPR-GRRSHSPLGFFSPSVPSRSPLPERE 197
             P T  AGPG   + R  RR H   G   P+V    P P +E
Sbjct: 451 SEPSTRAAGPGRFRDNRMDRREH---GHRDPNVVPGPPKPAKE 490


>gi|41152074 steroid-sensitive protein 1 [Homo sapiens]
          Length = 950

 Score = 45.4 bits (106), Expect = 9e-05
 Identities = 62/223 (27%), Positives = 88/223 (39%), Gaps = 35/223 (15%)

Query: 7   KFRKKNKDEKNTSSGLQRQ--ATHRDTPHLVTLGFCGTPGQKHFPKK---PP-------- 53
           K R+K   +K  +SG++ Q  A   D          G+  +K  P++   PP        
Sbjct: 271 KIRQKGFVQKCKASGVEGQVVAEGNDGGGGAGRPSLGSEKKKEDPRRAQVPPTRESRVKV 330

Query: 54  LQSLPARRRATPRRRARVRVT--PPVGRGGLLSSWSRA---APTPRSAAEAP----PGSA 104
           L+ L A   A P+  +  R T  PP     +  S SRA   A  P +    P    P + 
Sbjct: 331 LRKLAATAPALPQPPSTPRATTLPPAPATTVTRSTSRAVTVAARPMTTTAFPTTQRPWTP 390

Query: 105 IPAHLPRSVQRVLGARRTE------PRSAGERRRALPAAAGRKTKTWQSQ---NQSPRSA 155
            P+H P +   V+ ARR        P S  ++ R  P    R +K    +   N  P + 
Sbjct: 391 SPSHRPPTTTEVITARRPSVSENLYPPSRKDQHRERPQTTRRPSKATSLESFTNAPPTTI 450

Query: 156 RAPHTAGAGPGPGPEPR-GRRSHSPLGFFSPSVPSRSPLPERE 197
             P T  AGPG   + R  RR H   G   P+V    P P +E
Sbjct: 451 SEPSTRAAGPGRFRDNRMDRREH---GHRDPNVVPGPPKPAKE 490


>gi|169167740 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 302

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 40/129 (31%), Positives = 53/129 (41%), Gaps = 13/129 (10%)

Query: 100 PPGSAIPAHLPRSVQRVLGARRTEPRSAGERRRALPAAAGRKTKTWQSQNQS---PRSAR 156
           PPG A P H PR  +  +   +    S  +  R LPA    +  TW    +S   PR AR
Sbjct: 118 PPGRAPPRHAPRFPRPRMRFPQAWKASRAKEPRGLPA----QRPTWGPGTRSRGPPRQAR 173

Query: 157 APHTAGAGPGPGPEPRGRRSHSPLGFFSPSVPSRSPLPEREPERTDDRSRVESSARAGDQ 216
           + H   +   P PE RG  +  P       VP R P+      R+    R   SA  G  
Sbjct: 174 SQHPERS---PEPEGRGNHARKPAAL---PVPGRFPIRPVLGGRSGPGDRSLRSAHLGGA 227

Query: 217 RRGREPTSR 225
            +GR  T+R
Sbjct: 228 GQGRPWTAR 236


>gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens]
          Length = 1007

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 43/170 (25%), Positives = 65/170 (38%), Gaps = 33/170 (19%)

Query: 117 LGARRTEPRSAGERRRALPAAAGRKTKTWQSQNQSPRSARAPHTAGAGPG---------P 167
           L  +  + RS  + R++  +   ++ K  +S ++   S +   +    PG         P
Sbjct: 298 LRGKSKDRRSRSKERKSKRSETDKEKKPIKSPSKDASSGKENRSPSRRPGRSPKRRSLSP 357

Query: 168 GPEPRGRRSHSPLGFFSPSVPSRSPLPEREPERTDDRSRVESSARAGDQRRGREPTSR-- 225
            P  + RRS SPL     S  S+SP     P R      +E   R  ++RR   P +R  
Sbjct: 358 KPRDKSRRSRSPLLNDRRSKQSKSPSRTLSPGRRAKSRSLERKRREPERRRLSSPRTRPR 417

Query: 226 ----------------DHRAATRRAAHGPFRRRER------RKPRPRSES 253
                           +  + TRR +  P RRR R      R PR RS S
Sbjct: 418 DDILSRRERSKDASPINRWSPTRRRSRSPIRRRSRSPLRRSRSPRRRSRS 467



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 39/131 (29%), Positives = 58/131 (44%), Gaps = 15/131 (11%)

Query: 172 RGRRSHSPLGFFSPSVPSRSPLPEREPERTD-DRSRVESSARAGDQRRGREPTSRDHRAA 230
           RG++S SP+     S   RS   ER+ +R++ D+ +    + + D   G+E     +R+ 
Sbjct: 288 RGKKSRSPVDLRGKSKDRRSRSKERKSKRSETDKEKKPIKSPSKDASSGKE-----NRSP 342

Query: 231 TRRAAHGPFRRRERRKPRPRSESSQLACHLDLCFKWLPVASSRRPVAEAEPGRPEFGSAS 290
           +RR    P RR    KPR +S  S+     D   K      S+ P     PGR     A 
Sbjct: 343 SRRPGRSPKRRSLSPKPRDKSRRSRSPLLNDRRSK-----QSKSPSRTLSPGR----RAK 393

Query: 291 TRGCEEGRRVP 301
           +R  E  RR P
Sbjct: 394 SRSLERKRREP 404



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 58/228 (25%), Positives = 92/228 (40%), Gaps = 22/228 (9%)

Query: 3   KKSIKFRKKNKDEKNTSSGLQ--RQATHRDTPHLVTLGFCGTPGQKH-FPKKPPLQSLPA 59
           +  +  R K+KD ++ S   +  R  T ++   + +     + G+++  P + P +S P 
Sbjct: 293 RSPVDLRGKSKDRRSRSKERKSKRSETDKEKKPIKSPSKDASSGKENRSPSRRPGRS-PK 351

Query: 60  RRRATPRRRARVRVTPPVGRGGLLSSWSRAAPTPRSAAEAPPGSAIPAHLPRSVQRVLGA 119
           RR  +P+ R + R +    R  LL+   R+  +   +    PG        R+  R L  
Sbjct: 352 RRSLSPKPRDKSRRS----RSPLLND-RRSKQSKSPSRTLSPGR-------RAKSRSLER 399

Query: 120 RRTEPRSAGERRRALPAAAGRKTKTWQSQNQSPRSARAPHTAGAGPGPGPEPRGRRSHSP 179
           +R EP      RR L +   R      S+ +  + A   +           P  RRS SP
Sbjct: 400 KRREPE-----RRRLSSPRTRPRDDILSRRERSKDASPINRWSPTRRRSRSPIRRRSRSP 454

Query: 180 LGFF-SPSVPSRSPLPEREPERTDDRSRVESSARAGDQRRGREPTSRD 226
           L    SP   SRSP       R+  R R  S +R G +RR R     D
Sbjct: 455 LRRSRSPRRRSRSPRRRDRGRRSRSRLRRRSRSRGGRRRRSRSKVKED 502



 Score = 32.7 bits (73), Expect = 0.62
 Identities = 35/133 (26%), Positives = 54/133 (40%), Gaps = 10/133 (7%)

Query: 125 RSAGERRRALPAAAGRKTKTWQSQNQSPRSARAPHTAGAGPGPGPEP---RGRRSHSPLG 181
           R  G++ R+ P     K+K  +S+++  +S R+       P   P      G+ + SP  
Sbjct: 286 RDRGKKSRS-PVDLRGKSKDRRSRSKERKSKRSETDKEKKPIKSPSKDASSGKENRSP-- 342

Query: 182 FFSPSVPSRSPLPEREPERTDDRSRVESSARAGDQRRGREPTSRDHRAATRRAAHGPFRR 241
                 P RSP       +  D+SR   S    D RR ++  S     +  R A      
Sbjct: 343 ---SRRPGRSPKRRSLSPKPRDKSRRSRSPLLND-RRSKQSKSPSRTLSPGRRAKSRSLE 398

Query: 242 RERRKPRPRSESS 254
           R+RR+P  R  SS
Sbjct: 399 RKRREPERRRLSS 411


>gi|182507165 thymus expressed gene 3-like [Homo sapiens]
          Length = 629

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 64/242 (26%), Positives = 90/242 (37%), Gaps = 25/242 (10%)

Query: 38  GFCGTPGQKHFPKKPPLQSLPARRRATPRRRARVR------VTPPVGRGGLLSSW-SRAA 90
           G  G P +++  ++ P  + P+   A P R   +        +P        SSW S AA
Sbjct: 274 GADGGPRRQNSVRQRPPDASPSPGSARPAREPSLERVGGHPTSPAALSRAWASSWESEAA 333

Query: 91  PTPRS--AAEAPPGSAIPAHLPRSVQRVLGARRTEPRSAGE--RRRALPAAAGRKTKTWQ 146
           P P +  AA +PP S     L ++ Q + GA+       G   RR+  P   GR  +   
Sbjct: 334 PEPAAPPAAPSPPDSPAEGRLVKA-QYIPGAQAATRGLPGRAARRKPPPLTRGRSVEQ-S 391

Query: 147 SQNQSPRSARAPHTAGAGPGPGPEPRGRRSH------SPLGFFS--PSVPSRSPLPEREP 198
              + PR+A          G    PR R++       S LG  S  PS P + P  ERE 
Sbjct: 392 PPRERPRAAGRRGRMAEASGRRGSPRARKASRSQSETSLLGRASAVPSGPPKYPTAEREE 451

Query: 199 ERTDDRSR----VESSARAGDQRRGREPTSRDHRAATRRAAHGPFRRRERRKPRPRSESS 254
            R     R      ++  AG  RR R     D     R     P  R     P P +   
Sbjct: 452 PRPPRPRRGPAPTLAAQAAGSCRRWRSTAEIDAADGRRVRPRAPAARVPGPGPSPSAPQR 511

Query: 255 QL 256
           +L
Sbjct: 512 RL 513


>gi|113416994 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 302

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 40/129 (31%), Positives = 53/129 (41%), Gaps = 13/129 (10%)

Query: 100 PPGSAIPAHLPRSVQRVLGARRTEPRSAGERRRALPAAAGRKTKTWQSQNQS---PRSAR 156
           PPG A P H PR  +  +   +    S  +  R LPA    +  TW    +S   PR AR
Sbjct: 118 PPGRAPPRHAPRFPRPRMRFPQAWKASRAKEPRGLPA----QRPTWGPGTRSRGPPRRAR 173

Query: 157 APHTAGAGPGPGPEPRGRRSHSPLGFFSPSVPSRSPLPEREPERTDDRSRVESSARAGDQ 216
           + H   +   P PE RG  +  P       VP R P+      R+    R   SA  G  
Sbjct: 174 SQHPERS---PEPEGRGNHARKPAAL---PVPGRFPIRPVLGGRSGPGDRSLRSAHLGGA 227

Query: 217 RRGREPTSR 225
            +GR  T+R
Sbjct: 228 GQGRPWTAR 236



 Score = 30.0 bits (66), Expect = 4.0
 Identities = 60/243 (24%), Positives = 72/243 (29%), Gaps = 69/243 (28%)

Query: 154 SARAPHTAGAG--------PGPGPEPRGRRSHSPLGFFSPSVPSRSPLPEREPERTDDRS 205
           SA AP  AG G        P  G +   R  H P G   P    R P P     +    S
Sbjct: 86  SAEAPAPAGPGTTRRAGHMPASG-QVEARNDHRPPGRAPPRHAPRFPRPRMRFPQAWKAS 144

Query: 206 RVESSARAGDQRRGREPTSRDHRAATRRAAHGPFRRRERRKPRPRSESSQLACHLDLCFK 265
           R +       QR    P +R         + GP RR   + P    E      H      
Sbjct: 145 RAKEPRGLPAQRPTWGPGTR---------SRGPPRRARSQHPERSPEPEGRGNH------ 189

Query: 266 WLPVASSRRPVAEAEPG----RPEFGSASTRGCEEGRRVPRGTGSTCLRTDGGSLCSEKT 321
                 +R+P A   PG    RP  G  S            G G   LR+          
Sbjct: 190 ------ARKPAALPVPGRFPIRPVLGGRS------------GPGDRSLRS---------- 221

Query: 322 QTPEGGCETERPVSVRLALFICLLPRRLQPLIPAHPVRKQTAASPTATRRGRLPRAGQAG 381
               GG    RP + R             P IP    R + A S   T R   PR   A 
Sbjct: 222 -AHLGGAGQGRPWTAR------------PPPIPHTRPRPKCACSAPGTNRNLGPRVAGAN 268

Query: 382 QAA 384
            +A
Sbjct: 269 HSA 271


>gi|113416470 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 302

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 40/129 (31%), Positives = 53/129 (41%), Gaps = 13/129 (10%)

Query: 100 PPGSAIPAHLPRSVQRVLGARRTEPRSAGERRRALPAAAGRKTKTWQSQNQS---PRSAR 156
           PPG A P H PR  +  +   +    S  +  R LPA    +  TW    +S   PR AR
Sbjct: 118 PPGRAPPRHAPRFPRPRMRFPQAWKASRAKEPRGLPA----QRPTWGPGTRSRGPPRRAR 173

Query: 157 APHTAGAGPGPGPEPRGRRSHSPLGFFSPSVPSRSPLPEREPERTDDRSRVESSARAGDQ 216
           + H   +   P PE RG  +  P       VP R P+      R+    R   SA  G  
Sbjct: 174 SQHPERS---PEPEGRGNHARKPAAL---PVPGRFPIRPVLGGRSGPGDRSLRSAHLGGA 227

Query: 217 RRGREPTSR 225
            +GR  T+R
Sbjct: 228 GQGRPWTAR 236



 Score = 30.0 bits (66), Expect = 4.0
 Identities = 60/243 (24%), Positives = 72/243 (29%), Gaps = 69/243 (28%)

Query: 154 SARAPHTAGAG--------PGPGPEPRGRRSHSPLGFFSPSVPSRSPLPEREPERTDDRS 205
           SA AP  AG G        P  G +   R  H P G   P    R P P     +    S
Sbjct: 86  SAEAPAPAGPGTTRRAGHMPASG-QVEARNDHRPPGRAPPRHAPRFPRPRMRFPQAWKAS 144

Query: 206 RVESSARAGDQRRGREPTSRDHRAATRRAAHGPFRRRERRKPRPRSESSQLACHLDLCFK 265
           R +       QR    P +R         + GP RR   + P    E      H      
Sbjct: 145 RAKEPRGLPAQRPTWGPGTR---------SRGPPRRARSQHPERSPEPEGRGNH------ 189

Query: 266 WLPVASSRRPVAEAEPG----RPEFGSASTRGCEEGRRVPRGTGSTCLRTDGGSLCSEKT 321
                 +R+P A   PG    RP  G  S            G G   LR+          
Sbjct: 190 ------ARKPAALPVPGRFPIRPVLGGRS------------GPGDRSLRS---------- 221

Query: 322 QTPEGGCETERPVSVRLALFICLLPRRLQPLIPAHPVRKQTAASPTATRRGRLPRAGQAG 381
               GG    RP + R             P IP    R + A S   T R   PR   A 
Sbjct: 222 -AHLGGAGQGRPWTAR------------PPPIPHTRPRPKCACSTPGTNRNLGPRVAGAN 268

Query: 382 QAA 384
            +A
Sbjct: 269 HSA 271


>gi|209862765 RUN and SH3 domain containing 2 [Homo sapiens]
          Length = 1516

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 56/222 (25%), Positives = 81/222 (36%), Gaps = 26/222 (11%)

Query: 165 PGPGPEPRGRRSHSPLGFFSPSVPSRSPLPEREPERTDDRSRVESSARAGDQRRGREPTS 224
           PGPGP+P             PS PS   L ++   + +++  V SS +A        PT 
Sbjct: 431 PGPGPDP------------GPSQPSEYYLFQKPEVQPEEQEAVSSSTQAA---AAVGPTV 475

Query: 225 RDHRAATRRAAHGPFRRRERRKPRPRSESSQLACHLDLCFKWL--PVASSRRPVAEAEPG 282
            + +  T  +       R+R +   RS        L    + L  PV  S  P A A PG
Sbjct: 476 LEGQVYTNTSPPNLSTGRQRSRSYDRSLQRSPPVRLGSLERMLSCPVRLSEGPAAMAGPG 535

Query: 283 RPEFGSASTRGCEEGRRVPRGTGSTCLRTDGGSLCSEKTQTPEGGCETERPVSVRLALFI 342
            P     S     +GR+   G+GS  LR   G    E +   E   +   P+        
Sbjct: 536 SPPRRVTSFAELAKGRKKTGGSGSPPLRVSVGDSSQEFSPIQEAQQDRGAPLDEGTCCSH 595

Query: 343 CLLPRRLQPLI------PAHPVRKQTAASPTATRRGRLPRAG 378
            L P  L P +      P+ P   Q    P ++    +P AG
Sbjct: 596 SLPPMPLGPGMDLLGPDPSPPWSTQVCQGPHSS---EMPPAG 634



 Score = 32.3 bits (72), Expect = 0.81
 Identities = 22/86 (25%), Positives = 32/86 (37%), Gaps = 1/86 (1%)

Query: 87   SRAAPTPRSAAEAPPGSAIPAHLPRSVQRVLGARRTEPRSAGERRRALPAAAGRKTKTWQ 146
            SR  P P+ + + P   A+P+  P  VQ +     T P      +  +    GR    W 
Sbjct: 1426 SRREPEPKESLQEPHSPALPSSPPCEVQALCHHLATGPGQLSFHKGDILRVLGRAGGDWL 1485

Query: 147  SQNQSPRSARAPHT-AGAGPGPGPEP 171
              ++ P S   P       P P P P
Sbjct: 1486 RCSRGPDSGLVPLAYVTLTPTPSPTP 1511



 Score = 30.8 bits (68), Expect = 2.4
 Identities = 38/163 (23%), Positives = 59/163 (36%), Gaps = 20/163 (12%)

Query: 23  QRQATHRDTPHLVTLGFCGTPGQKHFPKKPPLQSLPARRRATPRRRARVRVTPPVGRGGL 82
           +++A    T     +G     GQ +    PP  S   R+R+    R+  R +PPV  G L
Sbjct: 457 EQEAVSSSTQAAAAVGPTVLEGQVYTNTSPPNLST-GRQRSRSYDRSLQR-SPPVRLGSL 514

Query: 83  LSSWSRAAPTPRSAAEAPPGSAIPAHLPRSVQRVLGARRTEPRSAGERRRALPAAAGRKT 142
                R    P   +E P   A P   PR V       +   ++ G     L  + G  +
Sbjct: 515 ----ERMLSCPVRLSEGPAAMAGPGSPPRRVTSFAELAKGRKKTGGSGSPPLRVSVGDSS 570

Query: 143 KTWQSQNQSPRSARAPHTAGA-----------GPGP---GPEP 171
           + +    ++ +   AP   G            GPG    GP+P
Sbjct: 571 QEFSPIQEAQQDRGAPLDEGTCCSHSLPPMPLGPGMDLLGPDP 613


>gi|55741719 RUN and SH3 domain containing 2 [Homo sapiens]
          Length = 1516

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 56/222 (25%), Positives = 81/222 (36%), Gaps = 26/222 (11%)

Query: 165 PGPGPEPRGRRSHSPLGFFSPSVPSRSPLPEREPERTDDRSRVESSARAGDQRRGREPTS 224
           PGPGP+P             PS PS   L ++   + +++  V SS +A        PT 
Sbjct: 431 PGPGPDP------------GPSQPSEYYLFQKPEVQPEEQEAVSSSTQAA---AAVGPTV 475

Query: 225 RDHRAATRRAAHGPFRRRERRKPRPRSESSQLACHLDLCFKWL--PVASSRRPVAEAEPG 282
            + +  T  +       R+R +   RS        L    + L  PV  S  P A A PG
Sbjct: 476 LEGQVYTNTSPPNLSTGRQRSRSYDRSLQRSPPVRLGSLERMLSCPVRLSEGPAAMAGPG 535

Query: 283 RPEFGSASTRGCEEGRRVPRGTGSTCLRTDGGSLCSEKTQTPEGGCETERPVSVRLALFI 342
            P     S     +GR+   G+GS  LR   G    E +   E   +   P+        
Sbjct: 536 SPPRRVTSFAELAKGRKKTGGSGSPPLRVSVGDSSQEFSPIQEAQQDRGAPLDEGTCCSH 595

Query: 343 CLLPRRLQPLI------PAHPVRKQTAASPTATRRGRLPRAG 378
            L P  L P +      P+ P   Q    P ++    +P AG
Sbjct: 596 SLPPMPLGPGMDLLGPDPSPPWSTQVCQGPHSS---EMPPAG 634



 Score = 32.3 bits (72), Expect = 0.81
 Identities = 22/86 (25%), Positives = 32/86 (37%), Gaps = 1/86 (1%)

Query: 87   SRAAPTPRSAAEAPPGSAIPAHLPRSVQRVLGARRTEPRSAGERRRALPAAAGRKTKTWQ 146
            SR  P P+ + + P   A+P+  P  VQ +     T P      +  +    GR    W 
Sbjct: 1426 SRREPEPKESLQEPHSPALPSSPPCEVQALCHHLATGPGQLSFHKGDILRVLGRAGGDWL 1485

Query: 147  SQNQSPRSARAPHT-AGAGPGPGPEP 171
              ++ P S   P       P P P P
Sbjct: 1486 RCSRGPDSGLVPLAYVTLTPTPSPTP 1511



 Score = 30.8 bits (68), Expect = 2.4
 Identities = 38/163 (23%), Positives = 59/163 (36%), Gaps = 20/163 (12%)

Query: 23  QRQATHRDTPHLVTLGFCGTPGQKHFPKKPPLQSLPARRRATPRRRARVRVTPPVGRGGL 82
           +++A    T     +G     GQ +    PP  S   R+R+    R+  R +PPV  G L
Sbjct: 457 EQEAVSSSTQAAAAVGPTVLEGQVYTNTSPPNLST-GRQRSRSYDRSLQR-SPPVRLGSL 514

Query: 83  LSSWSRAAPTPRSAAEAPPGSAIPAHLPRSVQRVLGARRTEPRSAGERRRALPAAAGRKT 142
                R    P   +E P   A P   PR V       +   ++ G     L  + G  +
Sbjct: 515 ----ERMLSCPVRLSEGPAAMAGPGSPPRRVTSFAELAKGRKKTGGSGSPPLRVSVGDSS 570

Query: 143 KTWQSQNQSPRSARAPHTAGA-----------GPGP---GPEP 171
           + +    ++ +   AP   G            GPG    GP+P
Sbjct: 571 QEFSPIQEAQQDRGAPLDEGTCCSHSLPPMPLGPGMDLLGPDP 613


>gi|169214061 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 384

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 74/255 (29%), Positives = 92/255 (36%), Gaps = 51/255 (20%)

Query: 48  FPKKPPLQSLP------ARRRATPRRRARVRVTPPVGRGGLLSSWSRAAPTPR------- 94
           +P+K P   LP      +  R T  RR +    P + RG    S  +AA   R       
Sbjct: 61  WPQKHPYHLLPELPTQISSSRPTRPRRCKSSSRPHLARGR--RSPLKAAQQDRGLPAWGV 118

Query: 95  ---SAAEAPPGSAIPAHLPRSVQRVLGARRTEPRSAGE-------RRRALPAAAGRKTKT 144
              S AE  P SA+      S +R LG +    R A E       R+R  P     +   
Sbjct: 119 WLLSRAEVRPRSALG-----SSRRGLGDKGPRSRRAAEFTQARPTRKRRTPGGGRPEAGC 173

Query: 145 WQSQNQSPRSARAPHTAGAGPG-PGPEPRGRRS-HSPLGFFSPSVPSRSP---------L 193
           W    +  R       AGAGP    P P G     SP    +P  P + P         L
Sbjct: 174 WLENRRQRRRKAGAERAGAGPTLTPPLPAGSPDPPSPAATAAPQ-PEQRPHLSRGQWRLL 232

Query: 194 PEREPERTDDRSRVESSARAGDQRRGREPTSRDHRAATRR--AAHGPF--RRRERRK--- 246
           P R PER    +   SS RA          +    A  R   A  GPF   RR RR+   
Sbjct: 233 PRRRPERAAGSAGSCSSRRALPASGSGAAMTGSWAAPPRPAWAGLGPFWHLRRSRRQDGL 292

Query: 247 --PRPRSESSQLACH 259
             P PR  SS +A H
Sbjct: 293 CCPGPRPPSSTVASH 307


>gi|169214437 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 384

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 74/255 (29%), Positives = 92/255 (36%), Gaps = 51/255 (20%)

Query: 48  FPKKPPLQSLP------ARRRATPRRRARVRVTPPVGRGGLLSSWSRAAPTPR------- 94
           +P+K P   LP      +  R T  RR +    P + RG    S  +AA   R       
Sbjct: 61  WPQKHPYHLLPELPTQISSSRPTRPRRCKSSSRPHLARGR--RSPLKAAQQDRGLPAWGV 118

Query: 95  ---SAAEAPPGSAIPAHLPRSVQRVLGARRTEPRSAGE-------RRRALPAAAGRKTKT 144
              S AE  P SA+      S +R LG +    R A E       R+R  P     +   
Sbjct: 119 WLLSRAEVRPRSALG-----SSRRGLGDKGPRSRRAAEFTQARPTRKRRTPGGGRPEAGC 173

Query: 145 WQSQNQSPRSARAPHTAGAGPG-PGPEPRGRRS-HSPLGFFSPSVPSRSP---------L 193
           W    +  R       AGAGP    P P G     SP    +P  P + P         L
Sbjct: 174 WLENRRQRRRKAGAERAGAGPTLTPPLPAGSPDPPSPAATAAPQ-PEQRPHLSRGQWRLL 232

Query: 194 PEREPERTDDRSRVESSARAGDQRRGREPTSRDHRAATRR--AAHGPF--RRRERRK--- 246
           P R PER    +   SS RA          +    A  R   A  GPF   RR RR+   
Sbjct: 233 PRRRPERAAGSAGSCSSRRALPASGSGAAMTGSWAAPPRPAWAGLGPFWHLRRSRRQDGL 292

Query: 247 --PRPRSESSQLACH 259
             P PR  SS +A H
Sbjct: 293 CCPGPRPPSSTVASH 307


>gi|169213353 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 384

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 74/255 (29%), Positives = 92/255 (36%), Gaps = 51/255 (20%)

Query: 48  FPKKPPLQSLP------ARRRATPRRRARVRVTPPVGRGGLLSSWSRAAPTPR------- 94
           +P+K P   LP      +  R T  RR +    P + RG    S  +AA   R       
Sbjct: 61  WPQKHPYHLLPELPTQISSSRPTRPRRCKSSSRPHLARGR--RSPLKAAQQDRGLPAWGV 118

Query: 95  ---SAAEAPPGSAIPAHLPRSVQRVLGARRTEPRSAGE-------RRRALPAAAGRKTKT 144
              S AE  P SA+      S +R LG +    R A E       R+R  P     +   
Sbjct: 119 WLLSRAEVRPRSALG-----SSRRGLGDKGPRSRRAAEFTQARPTRKRRTPGGGRPEAGC 173

Query: 145 WQSQNQSPRSARAPHTAGAGPG-PGPEPRGRRS-HSPLGFFSPSVPSRSP---------L 193
           W    +  R       AGAGP    P P G     SP    +P  P + P         L
Sbjct: 174 WLENRRQRRRKAGAERAGAGPTLTPPLPAGSPDPPSPAATAAPQ-PEQRPHLSRGQWRLL 232

Query: 194 PEREPERTDDRSRVESSARAGDQRRGREPTSRDHRAATRR--AAHGPF--RRRERRK--- 246
           P R PER    +   SS RA          +    A  R   A  GPF   RR RR+   
Sbjct: 233 PRRRPERAAGSAGSCSSRRALPASGSGAAMTGSWAAPPRPAWAGLGPFWHLRRSRRQDGL 292

Query: 247 --PRPRSESSQLACH 259
             P PR  SS +A H
Sbjct: 293 CCPGPRPPSSTVASH 307


>gi|239742598 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 296

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 62/214 (28%), Positives = 75/214 (35%), Gaps = 43/214 (20%)

Query: 91  PTPRSAAEAPPGSAIPAHLPRSVQRVLGARRTEP-RSAGERRRALPAAAGRKTKTWQSQN 149
           P P+ +A  P        + R       +R  EP R  GERRRA P      TK W+   
Sbjct: 90  PKPKQSARTPS-----IQVGRGRGEGAASRSCEPARGGGERRRAFP-----HTKWWR--R 137

Query: 150 QSPRSARAPHTAGAGPGPGPEPRGRRSHSPLGFFSPSVPSRSPLPEREPERTDDRSRVES 209
              R     HT    P   P  R +   SP G   P++    P P+  P     R R  S
Sbjct: 138 GGGRRTWGRHT----PYGIPADRRQLDASP-GSRRPALVCARPSPQGPPTAGGPRRRSVS 192

Query: 210 SARAGDQRRGREPTSRDH---------RAATRRAAHGPFRRRERRKPRPRSESSQLACHL 260
           +       RG    SR H         R   RRA     R RERR+ R    S +L    
Sbjct: 193 AGLVLAGARGPARPSRPHPAVRAGERERTHLRRAPGAAGRARERRRSRANEWSRRL---- 248

Query: 261 DLCFKWLPVASSRRPVAEAEPGRPEFGSASTRGC 294
                   +A   RPV    PGR   G     GC
Sbjct: 249 --------LAGDLRPV----PGRTARGCQGECGC 270


>gi|188536004 zinc finger protein 469 [Homo sapiens]
          Length = 3925

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 85/340 (25%), Positives = 118/340 (34%), Gaps = 55/340 (16%)

Query: 13   KDEKNTSSGLQRQATHRDTPHLVTLGFCGTPGQKHFPKKPPL------QSLPARRRATP- 65
            + E   S G       +  P   +L   G  GQ    K+ PL      ++  AR R  P 
Sbjct: 3549 RPENEASPGSPGPLLQQALPLGASLPRPGARGQDAEGKRAPLVFSGKRRAPGARGRCAPD 3608

Query: 66   --------RRRARVRVTPPVGRGGLLSSWSRAAPTP----------RSAAEAPPGSA-IP 106
                    ++   V  +  V  GG   ++ + + T           RSAA  P  +   P
Sbjct: 3609 HFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSAASTPSKALKFP 3668

Query: 107  AHLPRSVQRVLGARRTEPRSAGERRRALPAAAGRKTKTWQSQNQSPRSARAPHTAGAGPG 166
             H PR   + +G+      + G      PA    K       + SPR        G G  
Sbjct: 3669 VH-PR---KAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRPGTK---TGGGSQ 3721

Query: 167  PGPEPRGRRSHSPLGFFSPSVPSRSPLPEREPERTDDRSRVESSARAGDQ---------R 217
            P P     +S +      PS PSRSP PER P R   +S  +    AG+Q          
Sbjct: 3722 PQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQGPHGSLGPKE 3781

Query: 218  RGREPTSRDH---RAATRRAAHGPFRRRERRKPR-PRSESSQLACHLDLCFKWLPVASS- 272
            +G   T R         R  + G F R      + PR+   Q      L  K  P + + 
Sbjct: 3782 KGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKPPRTPRKQATPSRVLPTKPKPNSQNK 3841

Query: 273  -RRPVAE---AEPG----RPEFGSASTRGCEEGRRVPRGT 304
             R P +E   AEPG    +   G A  +G    R   RGT
Sbjct: 3842 PRPPPSEQRKAEPGHTQRKDRLGKAFPQGRPLLRPPKRGT 3881



 Score = 33.5 bits (75), Expect = 0.37
 Identities = 46/161 (28%), Positives = 60/161 (37%), Gaps = 36/161 (22%)

Query: 87   SRAAPTPRSAAEAPPGSAIP-AHLPRSVQRVLGAR-RTEPRSAGERRRALPAAA------ 138
            S+A  TP S A  P  +A P    PR   R   AR R + RS G       A +      
Sbjct: 887  SKAGVTPESKAPPPLPAATPDPQTPRPGDRGCPARGRPKTRSLGLAPTEADAPSQGRQQR 946

Query: 139  -GRKTKTWQSQNQSPRSARAPHTAGAGPG--------------PGPEPRGRRSHSPLGFF 183
             G++ K ++    S  +A    + G G                P P PR  R+ +P    
Sbjct: 947  RGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGLGERPPPRPRRPRTQAPGSRA 1006

Query: 184  SPS--VPSRSPLPE--------REPERTDDRSRVESSARAG 214
             P+  VP  + LPE        R P R D R R    AR G
Sbjct: 1007 DPAPRVPRAAALPEETRSSRRRRLPPRKDPRKR---KARGG 1044



 Score = 30.4 bits (67), Expect = 3.1
 Identities = 44/190 (23%), Positives = 62/190 (32%), Gaps = 43/190 (22%)

Query: 49   PKKPPLQSLPARRRATPRRRARVRVTP--PVGRGGL---------------LSSWSRAAP 91
            P+ P   +LP   R++ RRR   R  P     RGG                L  +  A+ 
Sbjct: 1010 PRVPRAAALPEETRSSRRRRLPPRKDPRKRKARGGAWGKELILKIVQQKNRLREYDFASE 1069

Query: 92   TPRSAAEAPPGSAIPAHLPR-----SVQRVLGARRTEPRSAGERRRALPAAAGRKTKTWQ 146
            +       P G        R      V+   G R  EP+    R+ A   A G       
Sbjct: 1070 SEEDEQPPPRGPGFRGRRGRGEKRKEVELTQGPREDEPQK--PRKAARQEAGG------- 1120

Query: 147  SQNQSPRSARAPHTAGAGPGPGPEPRG----------RRSHSPLGFFSPSVPSRSPLPER 196
              + +P +   P  +  GPG  P+ RG           R   P     PSV  + PL   
Sbjct: 1121 --DGAPANPEEPGGSRPGPGRSPQARGPSRSLETGAAAREGGPKCADRPSVAPKDPLQVP 1178

Query: 197  EPERTDDRSR 206
                T + +R
Sbjct: 1179 TNTETSEETR 1188


>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
          Length = 841

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 57/232 (24%), Positives = 85/232 (36%), Gaps = 37/232 (15%)

Query: 55  QSLPARRRATPRRRARVRVTPP--VGRGGLLSSWSRAAPTPRSAAEAP-PGSAIPAHLPR 111
           QSLPA  RA         ++P          +SW R    P S   +P PG  +P   P 
Sbjct: 441 QSLPASPRARLSASTASELSPKSKARPSSPSTSWHR----PASPCPSPGPGHTLPPK-PP 495

Query: 112 SVQRVLGARRTEPRSAGERRRALPAAAGRKTKTWQSQNQS-PRSARAPHTAGAGPGPGPE 170
           S +    + +   R   E + + P+AAG + K+   +  S  + + AP +    P P P 
Sbjct: 496 SPRGTTASPKGRVRRKEEAKES-PSAAGPEDKSQSKRRASNEKESAAPASPAPSPAPSPT 554

Query: 171 PRGRRSHSPLG--------FFSPSVPSRSPLPEREPERTDDRSR-----VESSARAGDQR 217
           P   +   P            SP  P+    P +    T DR        E   +A +QR
Sbjct: 555 PAPPQKEQPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTTDREEATRLLAEKRRQAREQR 614

Query: 218 RGRE-----PTSRDHR---------AATRRAAHGPFRRRERRKPRPRSESSQ 255
              E        RD R         A  R       RRRE ++ R ++++ Q
Sbjct: 615 EREEQERRLQAERDKRMREEQLAREAEARAEREAEARRREEQEAREKAQAEQ 666


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 82/345 (23%), Positives = 114/345 (33%), Gaps = 49/345 (14%)

Query: 64  TPRRRARVRVTPPVGRGGLLSSWSRAAPTPRSAAEAPPG---SAIPAHLPRSVQRVLGAR 120
           TPR     R  PPV    L    +  A   +  AE   G   + IP   PR+        
Sbjct: 26  TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRA-------- 77

Query: 121 RTEPRSAGERRR---ALPAAAGRKTKTWQSQNQSPRSARAPHTAGAGPGPGP-------- 169
               RSAG   R   + P A+GR  +   ++N SP    +P  A     PGP        
Sbjct: 78  -GPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRI 136

Query: 170 -----EPRGRRSHSPLGFFSPSVPSR---SPLPEREPERTDDRSRVESS----ARAGDQR 217
                  RG+ + +P      +   R    P P         RSR   +     R     
Sbjct: 137 SAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSA 196

Query: 218 RGREPTSRDHRAATRRAAHGPFRRRERRKPRPRSESS-QLACHLDLCFKWLPVASSRRPV 276
           R R PT    ++ +  + H         + RP +    Q      L     P++S  R  
Sbjct: 197 RPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG 256

Query: 277 AEAEPGRPEFGSASTRGCEEGRRVPRGTGSTCLRTDG----GSLCSEKTQTPEGGCETER 332
             A  G P   +  ++   +G +  R    T  R D     G L S    TP      + 
Sbjct: 257 PSAR-GTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQS 315

Query: 333 ------PVSVRLALFICLL--PRRLQPLIPAHPVRKQTAASPTAT 369
                 P +   +   C L  P  L P  P+ P   QT  SP AT
Sbjct: 316 QAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPAT 360



 Score = 30.4 bits (67), Expect = 3.1
 Identities = 43/162 (26%), Positives = 57/162 (35%), Gaps = 12/162 (7%)

Query: 49  PKKPPLQ---SLPARRRATPRRRARVRVTPPVGRGGLLSSWSRAAPTPRSAAEAPPGSAI 105
           P  PP+Q   S PA    +P      +  P +    L    S  A  P S +  PP  A 
Sbjct: 443 PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP 502

Query: 106 PAHLPRSVQRVLGARRTEPRSAGERRRALPAAAGRKTKTWQSQNQSPRSARAPHTAGAGP 165
           P      +Q      +  P  A    +ALP+       ++  Q     SA  P +  A P
Sbjct: 503 PPLAAPPLQLAKPPPQAPPALATPPLQALPSPPA----SFPGQAPFSPSASLPMSPLATP 558

Query: 166 GPGPEPRGRRSHSPLGFFSPSVPSRSPL--PEREPERTDDRS 205
            P   P      +PL    PS P+   L  P R P    D S
Sbjct: 559 PPQAPP---VLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTS 597



 Score = 28.9 bits (63), Expect = 9.0
 Identities = 65/247 (26%), Positives = 80/247 (32%), Gaps = 49/247 (19%)

Query: 52  PPLQ---SLPARRRATPRRRARVRVTPPVGRGGLLSSWSRAAPTPRS--AAEAPPGSAIP 106
           PPLQ   S PA    +P      +  PP+    L      A P P++  A   PP  A+P
Sbjct: 477 PPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL----QLAKPPPQAPPALATPPLQALP 532

Query: 107 ---AHLPRSVQRVLGARRTEPRSAGERRRALPAAAGRKTKTWQSQNQSP--RSARAPHTA 161
              A  P        A       A    +A P  A    +   S   SP  ++ R P T 
Sbjct: 533 SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPT- 591

Query: 162 GAGPGPGPEPRGRRSHSPLGFFSPSVPSRSPLPEREPERTDDRSRVESSARAGDQRRGRE 221
              PGP     G R    L    P  PSRSP                SS  +G    G  
Sbjct: 592 ---PGPDTSVSGPRLTLALAPGPPPPPSRSP----------------SSTLSGPDLAGHS 632

Query: 222 PTSRDHRAATRRAAHGPFRRRERRKPRPRSESSQLACHLDLCFKWLPVASSRRPVA---- 277
            ++       R    GP        P P +E +  ACH        P A SR P      
Sbjct: 633 SSATSTPEELRGYDSGP-EGGAAASPPPDAELA--ACH--------PAAWSRGPAPPLAF 681

Query: 278 EAEPGRP 284
              PG P
Sbjct: 682 RGAPGAP 688


>gi|17136078 VGF nerve growth factor inducible precursor [Homo
           sapiens]
          Length = 615

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 47/173 (27%), Positives = 65/173 (37%), Gaps = 24/173 (13%)

Query: 82  LLSSWSRAAPTPRSAAEAPP----------GSAIPAHLPRSVQRVLGARRTEPRSAGERR 131
           LL +   AAP  R  A+ PP          G A+P     S   V GAR +EP+  GE  
Sbjct: 15  LLINGLGAAPPGRPEAQPPPLSSEHKEPVAGDAVPGPKDGSAPEVRGARNSEPQDEGELF 74

Query: 132 RALPAAAGRKTKTWQSQNQSPRSARAPHTAGAGPGPGPEPRGR--------RSHSPLGFF 183
           + +   A              R A  P  +G+  GP  E            ++HS     
Sbjct: 75  QGVDPRALAAVLL----QALDRPASPPAPSGSQQGPEEEAAEALLTETVRSQTHSLPAPE 130

Query: 184 SP--SVPSRSPLPEREPERTDDRSRVESSARAGDQRRGREPTSRDHRAATRRA 234
           SP  + P R   PE  PE +D    +E+ A    + R   P+S   +  T  A
Sbjct: 131 SPEPAAPPRPQTPENGPEASDPSEELEALASLLQELRDFSPSSAKRQQETAAA 183



 Score = 30.8 bits (68), Expect = 2.4
 Identities = 33/116 (28%), Positives = 43/116 (37%), Gaps = 17/116 (14%)

Query: 89  AAPTPRSAAEAPPGSAIPAHLPRSVQRVLGARRTEPRSAGERRRALPAAAGRKTKTWQSQ 148
           A P P++    P  S     L      +   R   P SA  +R+   AAA  +T+T    
Sbjct: 136 APPRPQTPENGPEASDPSEELEALASLLQELRDFSPSSA--KRQQETAAAETETRTHTLT 193

Query: 149 NQSPRSARAPHTAGAGPGPGPEPRGRRSHSPLGFFSPSVPSRSPLPEREPERTDDR 204
             +  S            PGPE   R S    G F   VP R+PLP   P +   R
Sbjct: 194 RVNLES------------PGPERVWRASW---GEFQARVPERAPLPPPAPSQFQAR 234


>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
          Length = 715

 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 51/206 (24%), Positives = 78/206 (37%), Gaps = 39/206 (18%)

Query: 51  KPPLQSLPARRRATPRRRARVRVTPPVGRGGLLSSWSRAAPTPRSAAEAPPGSAIPAHLP 110
           KPP  SL + + ATP R + V   P   R  ++S      P+   + ++      P++ P
Sbjct: 27  KPPA-SLKSTKSATPNR-SLVPTKPATSRNSVMS------PSSSKSTKSTSTKRAPSNRP 78

Query: 111 RSVQRVLGARRTEPRSAGERRRALPAAAGRKTKTWQSQNQSPRSARAPHTAGAGPGPGPE 170
            S  RV    RT  R + + R +         K  ++ +      R  H+ G  PG    
Sbjct: 79  SSRSRVRSKARTPSRVSTDTRTS---------KASKASDVRCHQRRGTHSRGRTPGR--- 126

Query: 171 PRGRRSHSPLGFFSPSVPSRSPLPEREPERTDDRSRVES-SARAGDQRRGREPTSRDHRA 229
            RG RS                  +R P R     R+ +  AR G   R R PTS+   +
Sbjct: 127 -RGSRSS-----------------KRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGS 168

Query: 230 ATRRAAHGPFRRRERRKPRPRSESSQ 255
             +         RER   +PR+ S +
Sbjct: 169 RGKSYGRPRTSNRERSDSQPRNLSKK 194



 Score = 39.3 bits (90), Expect = 0.007
 Identities = 41/140 (29%), Positives = 56/140 (40%), Gaps = 18/140 (12%)

Query: 119 ARRTEPRSAGERRRALPAAAGRKTKTWQSQNQSPRSARAPHTAGAGPGPGPEPRGRRSHS 178
           +R   P  A +R R+   +  R      SQ  SP   R  H     P    + R  RS S
Sbjct: 462 SRSRSPNKARDRSRSRSPSKERD----HSQLGSPSKER-DHRRSRSPSKERQCRQSRSSS 516

Query: 179 PLGFFSPSVPSRSPLPERE------PERTDDRSRVESSARAGDQRRGREPTSRDHRAATR 232
                     SRSP  ER+      P +  DRS+  S +   + R+ R P+    +   R
Sbjct: 517 KE---RDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPS----KERDR 569

Query: 233 RAAHGPFRRRERRKPRPRSE 252
           R    P + RERR+ R  SE
Sbjct: 570 RRWRSPSKERERRQSRSSSE 589



 Score = 38.9 bits (89), Expect = 0.009
 Identities = 67/276 (24%), Positives = 103/276 (37%), Gaps = 37/276 (13%)

Query: 3   KKSIKFRKKNKDEKNTSSGLQRQATHRDTPHLVTLGFCGTPGQKHFPKKPPLQSLPARRR 62
           + S+     +K  K+TS+  +R  ++R +          TP +     +    S  +  R
Sbjct: 53  RNSVMSPSSSKSTKSTST--KRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVR 110

Query: 63  ATPRRRARVRVTPPVGRGGLLS--SWSRAAPTPRSAAE-APPGSAIPAHLPRSVQRVLGA 119
              RR    R   P  RG   S  S SRA+   R     A PG A     P S Q+  G+
Sbjct: 111 CHQRRGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQK--GS 168

Query: 120 RRTEPRSAGERRRALPAAAGRKTKTWQSQNQSPRSARAPHTAGAGPG------------- 166
           R    +S G      P  + R+    Q +N S +S R P  +G G               
Sbjct: 169 RG---KSYGR-----PRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQ 220

Query: 167 -PGPEPRGRRSHSPLGFFSPSVPSRS----PLPEREPERTDDRSRVES----SARAGDQR 217
            P   P   +S +P    S  V S      P  E+    T+  SRV+S    S R+  Q 
Sbjct: 221 TPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQS 280

Query: 218 RGREPTSRDHRAATRRAAHGPFRRRERRKPRPRSES 253
             +  + R  R+ +++  H   R    ++   R+ S
Sbjct: 281 HSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARS 316



 Score = 38.1 bits (87), Expect = 0.015
 Identities = 49/186 (26%), Positives = 75/186 (40%), Gaps = 36/186 (19%)

Query: 85  SWSRAAPTPRSAAEAPPGSAIPAHLPRSVQRVLGARRTEPRSAGERRRALPAAAGRKTKT 144
           S SR+    RS ++    S + +H           +R   R+    R+ + +  GR +++
Sbjct: 282 SQSRSPRRSRSGSQKRTHSRVRSH---------SWKRNHSRARSRTRKGILSQMGRHSQS 332

Query: 145 -----WQSQNQS--PRSARAPHTAGAGPGPGPEPRGRRSHSP----LGFFSP---SVPSR 190
                 +SQNQS  PR  R+ H     P         RS S      G  SP   S  S+
Sbjct: 333 RSHSKGKSQNQSRTPRRGRS-HNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQ 391

Query: 191 SPLPE--------REPERTDDRSRVESSARAGDQRRGREPTSRDHRAATRRAAHGPFRRR 242
           S  P         R P +  DRSR  S  +A D+ R R P    ++A     +  P++ R
Sbjct: 392 SGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSP----NKARDCSRSRSPYKAR 447

Query: 243 ERRKPR 248
           +R + R
Sbjct: 448 DRSRSR 453



 Score = 37.4 bits (85), Expect = 0.025
 Identities = 40/159 (25%), Positives = 63/159 (39%), Gaps = 26/159 (16%)

Query: 119 ARRTEPRSAGERRRALPAAAGRKTKTWQSQNQSP--RSARAPHTAGAGPGPGPEPRGRRS 176
           +R   P  A +R R+      R     +S N++     +R+P+ A         P   R 
Sbjct: 402 SRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKA-RDRSRSRSPNKARD 460

Query: 177 HSPLGFFSPSVPSRSPLPEREPERTDDRSRVESSARAGDQRRGREPT------------- 223
           HS     SP+  +R     R P +  D S++ S ++  D RR R P+             
Sbjct: 461 HSRSR--SPN-KARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSK 517

Query: 224 SRDHRAA-------TRRAAHGPFRRRERRKPRPRSESSQ 255
            RDHR +        RR +  P + R+R + R  SE  +
Sbjct: 518 ERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEERE 556



 Score = 37.0 bits (84), Expect = 0.033
 Identities = 58/228 (25%), Positives = 90/228 (39%), Gaps = 39/228 (17%)

Query: 45  QKHFPKKPPLQSLPARRRATPRR-----------RARVRVTPPVGRGGLLSSWSRAAPTP 93
           Q H   + P +S    ++ T  R           RAR R      R G+LS   R +   
Sbjct: 279 QSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRT-----RKGILSQMGRHS--- 330

Query: 94  RSAAEAPPGSAIPAHLPRSVQRVLGARR-------TEPRSAGERRRALPAAAGRKTKTWQ 146
           +S + +   S   +  PR  +    +R        +  RS+ + R    +++ RK ++ +
Sbjct: 331 QSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRK-ESGR 389

Query: 147 SQNQSPRSARAPHTAGAGPGPGPEPRGRRSHSPLGFFSPSVPSRSPLPEREPERTDDRSR 206
           SQ+ SP   R  H+    P    +    RS SP         +R     R P +  D SR
Sbjct: 390 SQSGSPNKQR-DHSRSRSPNKARDRS--RSRSPY-------KARDRSRSRSPNKARDCSR 439

Query: 207 VESSARAGDQRRGREPT-SRDH-RAATRRAAHGPFRRRERRKPRPRSE 252
             S  +A D+ R R P  +RDH R+ +   A    R R   K R  S+
Sbjct: 440 SRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQ 487



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 32/118 (27%), Positives = 48/118 (40%), Gaps = 13/118 (11%)

Query: 146 QSQNQSPRSARAPHTAGAGPGPGPEPRGRRSHSPLGFFSPSVPSRSPLPEREPERTDDRS 205
           + Q +  RS+           P  E + R+S SP      S  SRSP  ERE  ++    
Sbjct: 506 ERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRS-QSRSPSEEREHRQS---- 560

Query: 206 RVESSARAGDQRRGREPTSRDHRAATRRAAHGPFRRRERRK------PRPRSESSQLA 257
              S ++  D+RR R P+    R  +R ++      R R         RPR+ S + A
Sbjct: 561 --RSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKA 616



 Score = 30.8 bits (68), Expect = 2.4
 Identities = 32/147 (21%), Positives = 50/147 (34%), Gaps = 19/147 (12%)

Query: 112 SVQRVLGARRTEPRSAGERRRALPAAAGRKTKTWQSQNQSPRSARAPHTAGAGPGPGPEP 171
           S +R     R+  +    RR   P+         + Q +  RS            P  E 
Sbjct: 504 SKERQCRQSRSSSKERDHRRSRSPSK--------ERQRRQSRSPNKERDRSQSRSPSEER 555

Query: 172 RGRRSHSPLGFFSPSVPSRSPLPEREPERTDDRSRVESSARAGDQRRGREPTSRD----H 227
             R+S SP          R     R P +  +R +  SS+   D  R R P  +      
Sbjct: 556 EHRQSRSPS-------KERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRP 608

Query: 228 RAATRRAAHGPFRRRERRKPRPRSESS 254
           RA+++  AH   R   +     +S +S
Sbjct: 609 RASSKEKAHSRSRTPSKEGNHSQSRTS 635


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.131    0.405 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,801,048
Number of Sequences: 37866
Number of extensions: 1272807
Number of successful extensions: 9962
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 117
Number of HSP's successfully gapped in prelim test: 897
Number of HSP's that attempted gapping in prelim test: 7890
Number of HSP's gapped (non-prelim): 2527
length of query: 416
length of database: 18,247,518
effective HSP length: 105
effective length of query: 311
effective length of database: 14,271,588
effective search space: 4438463868
effective search space used: 4438463868
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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