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Search of human proteins with 118442841
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|118442841 hypothetical protein LOC123591 [Homo sapiens]
(531 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|118442841 hypothetical protein LOC123591 [Homo sapiens] 1035 0.0
gi|91992155 hydrogen voltage-gated channel 1 [Homo sapiens] 82 9e-16
gi|91992153 hydrogen voltage-gated channel 1 [Homo sapiens] 82 9e-16
gi|51093859 calcium channel, voltage-dependent, T type, alpha 1I... 49 1e-05
gi|21361077 calcium channel, voltage-dependent, T type, alpha 1I... 49 1e-05
gi|126362949 sodium channel, voltage-gated, type III, alpha isof... 45 1e-04
gi|126362955 sodium channel, voltage-gated, type III, alpha isof... 45 2e-04
gi|126362947 sodium channel, voltage-gated, type III, alpha isof... 45 2e-04
gi|55741677 SET domain containing 1A [Homo sapiens] 43 6e-04
gi|4502523 calcium channel, voltage-dependent, N type, alpha 1B ... 43 8e-04
gi|93141214 sodium channel, voltage-gated, type II, alpha isofor... 42 0.001
gi|93141212 sodium channel, voltage-gated, type II, alpha isofor... 42 0.001
gi|93141210 sodium channel, voltage-gated, type II, alpha isofor... 42 0.001
gi|111378393 sodium channel, voltage-gated, type VII, alpha [Hom... 42 0.002
gi|93587342 voltage-gated sodium channel type 4 alpha [Homo sapi... 41 0.003
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo... 40 0.004
gi|237512982 voltage-gated sodium channel type V alpha isoform f... 40 0.005
gi|237512980 voltage-gated sodium channel type V alpha isoform e... 40 0.005
gi|37622907 voltage-gated sodium channel type V alpha isoform a ... 40 0.005
gi|30089970 voltage-gated sodium channel type V alpha isoform b ... 40 0.005
gi|150417969 voltage-gated sodium channel type V alpha isoform d... 40 0.005
gi|150417967 voltage-gated sodium channel type V alpha isoform c... 40 0.005
gi|20070163 voltage-dependent calcium channel alpha 1G subunit i... 40 0.007
gi|38505294 voltage-dependent calcium channel alpha 1G subunit i... 40 0.007
gi|38505292 voltage-dependent calcium channel alpha 1G subunit i... 40 0.007
gi|38505290 voltage-dependent calcium channel alpha 1G subunit i... 40 0.007
gi|38505288 voltage-dependent calcium channel alpha 1G subunit i... 40 0.007
gi|38505286 voltage-dependent calcium channel alpha 1G subunit i... 40 0.007
gi|38505284 voltage-dependent calcium channel alpha 1G subunit i... 40 0.007
gi|38505282 voltage-dependent calcium channel alpha 1G subunit i... 40 0.007
>gi|118442841 hypothetical protein LOC123591 [Homo sapiens]
Length = 531
Score = 1035 bits (2676), Expect = 0.0
Identities = 531/531 (100%), Positives = 531/531 (100%)
Query: 1 MAVAPSFNMTNPQPAIEGGISEVEIISQQVDEETKSIAPVQLVNFAYRDLPLAAVDLSTA 60
MAVAPSFNMTNPQPAIEGGISEVEIISQQVDEETKSIAPVQLVNFAYRDLPLAAVDLSTA
Sbjct: 1 MAVAPSFNMTNPQPAIEGGISEVEIISQQVDEETKSIAPVQLVNFAYRDLPLAAVDLSTA 60
Query: 61 GSQLLSNLDEDYQREGSNWLKPCCGKRAAVWQVFLLSASLNSFLVACVILVVILLTLELL 120
GSQLLSNLDEDYQREGSNWLKPCCGKRAAVWQVFLLSASLNSFLVACVILVVILLTLELL
Sbjct: 61 GSQLLSNLDEDYQREGSNWLKPCCGKRAAVWQVFLLSASLNSFLVACVILVVILLTLELL 120
Query: 121 IDIKLLQFSSAFQFAGVIHWISLVILSVFFSETVLRIVVLGIWDYIENKIEVFDGAVIIL 180
IDIKLLQFSSAFQFAGVIHWISLVILSVFFSETVLRIVVLGIWDYIENKIEVFDGAVIIL
Sbjct: 121 IDIKLLQFSSAFQFAGVIHWISLVILSVFFSETVLRIVVLGIWDYIENKIEVFDGAVIIL 180
Query: 181 SLAPMVASTVANGPRSPWDAISLIIMLRIWRVKRVIDAYVLPVKLEMEMVIQQYEKAKVI 240
SLAPMVASTVANGPRSPWDAISLIIMLRIWRVKRVIDAYVLPVKLEMEMVIQQYEKAKVI
Sbjct: 181 SLAPMVASTVANGPRSPWDAISLIIMLRIWRVKRVIDAYVLPVKLEMEMVIQQYEKAKVI 240
Query: 241 QDEQLERLTQICQEQGFEIRQLRAHLAQQDLDLAAEREAALQAPHVLSQPRSRFKVLEAG 300
QDEQLERLTQICQEQGFEIRQLRAHLAQQDLDLAAEREAALQAPHVLSQPRSRFKVLEAG
Sbjct: 241 QDEQLERLTQICQEQGFEIRQLRAHLAQQDLDLAAEREAALQAPHVLSQPRSRFKVLEAG 300
Query: 301 TWDEETAAESVVEELQPSQEATMKDDMNSYISQYYNGPSSDSGVPEPAVCMVTTAAIDIH 360
TWDEETAAESVVEELQPSQEATMKDDMNSYISQYYNGPSSDSGVPEPAVCMVTTAAIDIH
Sbjct: 301 TWDEETAAESVVEELQPSQEATMKDDMNSYISQYYNGPSSDSGVPEPAVCMVTTAAIDIH 360
Query: 361 QPNISSDLFSLDMPLKLGGNGTSATSESASRSSVTRAQSDSSQTLGSSMDCSTAREEPSS 420
QPNISSDLFSLDMPLKLGGNGTSATSESASRSSVTRAQSDSSQTLGSSMDCSTAREEPSS
Sbjct: 361 QPNISSDLFSLDMPLKLGGNGTSATSESASRSSVTRAQSDSSQTLGSSMDCSTAREEPSS 420
Query: 421 EPGPSPPPLPSQQQVEEATVQDLLSSLSEDPCPSQKALDPAPLARPSPAGSAQTSPELEH 480
EPGPSPPPLPSQQQVEEATVQDLLSSLSEDPCPSQKALDPAPLARPSPAGSAQTSPELEH
Sbjct: 421 EPGPSPPPLPSQQQVEEATVQDLLSSLSEDPCPSQKALDPAPLARPSPAGSAQTSPELEH 480
Query: 481 RVSLFNQKNQEGFTVFQIRPVIHFQPTVPMLEDKFRSLESKEQKLHRVPEA 531
RVSLFNQKNQEGFTVFQIRPVIHFQPTVPMLEDKFRSLESKEQKLHRVPEA
Sbjct: 481 RVSLFNQKNQEGFTVFQIRPVIHFQPTVPMLEDKFRSLESKEQKLHRVPEA 531
>gi|91992155 hydrogen voltage-gated channel 1 [Homo sapiens]
Length = 273
Score = 82.4 bits (202), Expect = 9e-16
Identities = 46/168 (27%), Positives = 90/168 (53%), Gaps = 4/168 (2%)
Query: 104 LVACVILVVILLTLELLIDIKLLQFSSAFQFAGVIHWISLVILSVFFSETVLRIVVLGIW 163
++ V+L +L+ EL++D+K++Q A V H++S+ IL F E + ++ V +
Sbjct: 105 IICLVVLDALLVLAELILDLKIIQPDKNNYAAMVFHYMSITILVFFMMEIIFKLFVFRL- 163
Query: 164 DYIENKIEVFDGAVIILSLAPMVASTVANGPRSPWDAISLIIMLRIWRVKRVIDAYVLPV 223
++ +K E+ D V+++S + V ++A+ L+I+LR+WRV R+I+ ++ V
Sbjct: 164 EFFHHKFEILDAVVVVVSF---ILDIVLLFQEHQFEALGLLILLRLWRVARIINGIIISV 220
Query: 224 KLEMEMVIQQYEKAKVIQDEQLERLTQICQEQGFEIRQLRAHLAQQDL 271
K E + + ++ V +++ L C E+ EI +L L Q L
Sbjct: 221 KTRSERQLLRLKQMNVQLAAKIQHLEFSCSEKEQEIERLNKLLRQHGL 268
>gi|91992153 hydrogen voltage-gated channel 1 [Homo sapiens]
Length = 273
Score = 82.4 bits (202), Expect = 9e-16
Identities = 46/168 (27%), Positives = 90/168 (53%), Gaps = 4/168 (2%)
Query: 104 LVACVILVVILLTLELLIDIKLLQFSSAFQFAGVIHWISLVILSVFFSETVLRIVVLGIW 163
++ V+L +L+ EL++D+K++Q A V H++S+ IL F E + ++ V +
Sbjct: 105 IICLVVLDALLVLAELILDLKIIQPDKNNYAAMVFHYMSITILVFFMMEIIFKLFVFRL- 163
Query: 164 DYIENKIEVFDGAVIILSLAPMVASTVANGPRSPWDAISLIIMLRIWRVKRVIDAYVLPV 223
++ +K E+ D V+++S + V ++A+ L+I+LR+WRV R+I+ ++ V
Sbjct: 164 EFFHHKFEILDAVVVVVSF---ILDIVLLFQEHQFEALGLLILLRLWRVARIINGIIISV 220
Query: 224 KLEMEMVIQQYEKAKVIQDEQLERLTQICQEQGFEIRQLRAHLAQQDL 271
K E + + ++ V +++ L C E+ EI +L L Q L
Sbjct: 221 KTRSERQLLRLKQMNVQLAAKIQHLEFSCSEKEQEIERLNKLLRQHGL 268
>gi|51093859 calcium channel, voltage-dependent, T type, alpha 1I
subunit isoform b [Homo sapiens]
Length = 2188
Score = 48.5 bits (114), Expect = 1e-05
Identities = 37/172 (21%), Positives = 80/172 (46%), Gaps = 18/172 (10%)
Query: 60 AGSQLLSNLDEDYQREGSNWLKPCCGKRAAVWQVFLLSASLNSFLVACVILVVILLTLEL 119
A S+L +E+ Q +G+ WL CG + L + + +++ +++ T+ +
Sbjct: 566 ASSELGKEEEEEEQADGAVWL---CGDVWRETRAKLRGIVDSKYFNRGIMMAILVNTVSM 622
Query: 120 LIDIKLLQFSSAFQFAGVIHWISLVILSVFFSETVLRIVVLGIWDYIENKIEVFDGAVII 179
I+ + ++ ++V S+F E +L++ G++DY+ N +FD ++I
Sbjct: 623 GIE----HHEQPEELTNILEICNVVFTSMFALEMILKLAAFGLFDYLRNPYNIFDSIIVI 678
Query: 180 LSLAPMVASTVANGPRSPWDAISLIIMLRIWRVKRVIDAYVLPVKLEMEMVI 231
+S+ +V A+G S +LR +R+ RV+ L ++V+
Sbjct: 679 ISIWEIVGQ--ADGGLS---------VLRTFRLLRVLKLVRFMPALRRQLVV 719
Score = 38.1 bits (87), Expect = 0.020
Identities = 34/141 (24%), Positives = 61/141 (43%), Gaps = 17/141 (12%)
Query: 91 WQVFLLSASLNSFLVAC-----------VILVVILLTLELLIDIKLLQFSSAFQFAGVIH 139
W V+L S N F V C V+L I L + I ++ Q + +
Sbjct: 1113 WSVYLFSPE-NRFRVLCQTIIAHKLFDYVVLAFIFLNC-ITIALERPQIEAGSTERIFLT 1170
Query: 140 WISLVILSVFFSETVLRIVVLGIW----DYIENKIEVFDGAVIILSLAPMVASTVANGPR 195
+ + ++F E L++V LG++ Y+ + V DG ++ +S+ +V S + G
Sbjct: 1171 VSNYIFTAIFVGEMTLKVVSLGLYFGEQAYLRSSWNVLDGFLVFVSIIDIVVSLASAGGA 1230
Query: 196 SPWDAISLIIMLRIWRVKRVI 216
+ ++ +LR R RVI
Sbjct: 1231 KILGVLRVLRLLRTLRPLRVI 1251
>gi|21361077 calcium channel, voltage-dependent, T type, alpha 1I
subunit isoform a [Homo sapiens]
Length = 2223
Score = 48.5 bits (114), Expect = 1e-05
Identities = 37/172 (21%), Positives = 80/172 (46%), Gaps = 18/172 (10%)
Query: 60 AGSQLLSNLDEDYQREGSNWLKPCCGKRAAVWQVFLLSASLNSFLVACVILVVILLTLEL 119
A S+L +E+ Q +G+ WL CG + L + + +++ +++ T+ +
Sbjct: 601 ASSELGKEEEEEEQADGAVWL---CGDVWRETRAKLRGIVDSKYFNRGIMMAILVNTVSM 657
Query: 120 LIDIKLLQFSSAFQFAGVIHWISLVILSVFFSETVLRIVVLGIWDYIENKIEVFDGAVII 179
I+ + ++ ++V S+F E +L++ G++DY+ N +FD ++I
Sbjct: 658 GIE----HHEQPEELTNILEICNVVFTSMFALEMILKLAAFGLFDYLRNPYNIFDSIIVI 713
Query: 180 LSLAPMVASTVANGPRSPWDAISLIIMLRIWRVKRVIDAYVLPVKLEMEMVI 231
+S+ +V A+G S +LR +R+ RV+ L ++V+
Sbjct: 714 ISIWEIVGQ--ADGGLS---------VLRTFRLLRVLKLVRFMPALRRQLVV 754
Score = 38.1 bits (87), Expect = 0.020
Identities = 34/141 (24%), Positives = 61/141 (43%), Gaps = 17/141 (12%)
Query: 91 WQVFLLSASLNSFLVAC-----------VILVVILLTLELLIDIKLLQFSSAFQFAGVIH 139
W V+L S N F V C V+L I L + I ++ Q + +
Sbjct: 1148 WSVYLFSPE-NRFRVLCQTIIAHKLFDYVVLAFIFLNC-ITIALERPQIEAGSTERIFLT 1205
Query: 140 WISLVILSVFFSETVLRIVVLGIW----DYIENKIEVFDGAVIILSLAPMVASTVANGPR 195
+ + ++F E L++V LG++ Y+ + V DG ++ +S+ +V S + G
Sbjct: 1206 VSNYIFTAIFVGEMTLKVVSLGLYFGEQAYLRSSWNVLDGFLVFVSIIDIVVSLASAGGA 1265
Query: 196 SPWDAISLIIMLRIWRVKRVI 216
+ ++ +LR R RVI
Sbjct: 1266 KILGVLRVLRLLRTLRPLRVI 1286
>gi|126362949 sodium channel, voltage-gated, type III, alpha isoform
1 [Homo sapiens]
Length = 2000
Score = 45.4 bits (106), Expect = 1e-04
Identities = 43/211 (20%), Positives = 96/211 (45%), Gaps = 26/211 (12%)
Query: 17 EGGISEVEIISQQVDEETKSIAPVQLVNFAYRDLPLAAVDLSTAGSQLLSNLDEDYQREG 76
EG +E E+ +++ S+ ++ + R + +A++ +T + L+E Q+
Sbjct: 673 EGTTTETEVRKRRLSSYQISMEMLEDSSGRQRAVSIASILTNT-----MEELEESRQKCP 727
Query: 77 SNWLK--------PCCGKRAAVWQVFLLSASLNSFLVACVILVVILLTLELLIDIKLLQF 128
W + CC V + L ++ F+ + + ++L TL + ++ +
Sbjct: 728 PCWYRFANVFLIWDCCDAWLKVKHLVNLIV-MDPFVDLAITICIVLNTLFMAME----HY 782
Query: 129 SSAFQFAGVIHWISLVILSVFFSETVLRIVVLGIWDYIENKIEVFDGAVIILSLAPMVAS 188
QF+ V+ +LV +F +E VL+I+ + + Y + +FDG ++ LSL + S
Sbjct: 783 PMTEQFSSVLTVGNLVFTGIFTAEMVLKIIAMDPYYYFQEGWNIFDGIIVSLSLMELGLS 842
Query: 189 TVANGPRSPWDAISLIIMLRIWRVKRVIDAY 219
V + +S++ R+ RV ++ ++
Sbjct: 843 NV--------EGLSVLRSFRLLRVFKLAKSW 865
>gi|126362955 sodium channel, voltage-gated, type III, alpha isoform
3 [Homo sapiens]
Length = 1951
Score = 44.7 bits (104), Expect = 2e-04
Identities = 37/174 (21%), Positives = 80/174 (45%), Gaps = 21/174 (12%)
Query: 54 AVDLSTAGSQLLSNLDEDYQREGSNWLK--------PCCGKRAAVWQVFLLSASLNSFLV 105
AV +++ + + L+E Q+ W + CC V + L ++ F+
Sbjct: 656 AVSIASILTNTMEELEESRQKCPPCWYRFANVFLIWDCCDAWLKVKHLVNLIV-MDPFVD 714
Query: 106 ACVILVVILLTLELLIDIKLLQFSSAFQFAGVIHWISLVILSVFFSETVLRIVVLGIWDY 165
+ + ++L TL + ++ + QF+ V+ +LV +F +E VL+I+ + + Y
Sbjct: 715 LAITICIVLNTLFMAME----HYPMTEQFSSVLTVGNLVFTGIFTAEMVLKIIAMDPYYY 770
Query: 166 IENKIEVFDGAVIILSLAPMVASTVANGPRSPWDAISLIIMLRIWRVKRVIDAY 219
+ +FDG ++ LSL + S V + +S++ R+ RV ++ ++
Sbjct: 771 FQEGWNIFDGIIVSLSLMELGLSNV--------EGLSVLRSFRLLRVFKLAKSW 816
>gi|126362947 sodium channel, voltage-gated, type III, alpha isoform
2 [Homo sapiens]
Length = 1951
Score = 44.7 bits (104), Expect = 2e-04
Identities = 37/174 (21%), Positives = 80/174 (45%), Gaps = 21/174 (12%)
Query: 54 AVDLSTAGSQLLSNLDEDYQREGSNWLK--------PCCGKRAAVWQVFLLSASLNSFLV 105
AV +++ + + L+E Q+ W + CC V + L ++ F+
Sbjct: 656 AVSIASILTNTMEELEESRQKCPPCWYRFANVFLIWDCCDAWLKVKHLVNLIV-MDPFVD 714
Query: 106 ACVILVVILLTLELLIDIKLLQFSSAFQFAGVIHWISLVILSVFFSETVLRIVVLGIWDY 165
+ + ++L TL + ++ + QF+ V+ +LV +F +E VL+I+ + + Y
Sbjct: 715 LAITICIVLNTLFMAME----HYPMTEQFSSVLTVGNLVFTGIFTAEMVLKIIAMDPYYY 770
Query: 166 IENKIEVFDGAVIILSLAPMVASTVANGPRSPWDAISLIIMLRIWRVKRVIDAY 219
+ +FDG ++ LSL + S V + +S++ R+ RV ++ ++
Sbjct: 771 FQEGWNIFDGIIVSLSLMELGLSNV--------EGLSVLRSFRLLRVFKLAKSW 816
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 43.1 bits (100), Expect = 6e-04
Identities = 33/99 (33%), Positives = 50/99 (50%), Gaps = 11/99 (11%)
Query: 382 TSATSESASRSSVTRAQSDSSQTLGSSMDCSTAREEPSSEPGPSPP----PLPSQQQVEE 437
+S++S S+S SS + + S SS + SS + E P++ P SPP P+P+ V E
Sbjct: 1035 SSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSASPPPREVPVPTPAPV-E 1093
Query: 438 ATVQDLLSSLSEDPCPSQKALDPAPLARPSPAGSAQTSP 476
V + ++ P P Q+A PA PAG + SP
Sbjct: 1094 VPVPERVAGSPVTPLPEQEA-SPA-----RPAGPTEESP 1126
Score = 35.8 bits (81), Expect = 0.100
Identities = 28/112 (25%), Positives = 46/112 (41%), Gaps = 8/112 (7%)
Query: 380 NGTSATSESASRSSVTRAQSDSSQTLGSSMDCSTAREEPSSEPGPSPPPLPSQQQVEEAT 439
+ +S++S S+S SS + ++S S + P P P P P + V E
Sbjct: 1041 SSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSASPPPREVPVPTPAPVEVPVPERV 1100
Query: 440 VQDLLSSLSEDPC-------PSQKALDPAPLARPS-PAGSAQTSPELEHRVS 483
++ L E P++++ APL P PAG +P + R S
Sbjct: 1101 AGSPVTPLPEQEASPARPAGPTEESPPSAPLRPPEPPAGPPAPAPRPDERPS 1152
Score = 29.6 bits (65), Expect = 7.2
Identities = 28/93 (30%), Positives = 33/93 (35%), Gaps = 5/93 (5%)
Query: 378 GGNGTSATSESASRSSVTRAQSDSSQTLGSSMDCSTAREEPSSEPGPSPPPLPSQQQVEE 437
G AT ES + +A SS G M+ S S P P+PP P
Sbjct: 555 GSGEPGATRESPKANGQNQASPCSS---GDDMEISDDDRGGSPPPAPTPPQQPPPPPPPP 611
Query: 438 ATVQDLLSSLSEDPCPSQKA--LDPAPLARPSP 468
L+SL P Q A L P P P P
Sbjct: 612 PPPPPYLASLPLGYPPHQPAYLLPPRPDGPPPP 644
>gi|4502523 calcium channel, voltage-dependent, N type, alpha 1B
subunit [Homo sapiens]
Length = 2339
Score = 42.7 bits (99), Expect = 8e-04
Identities = 25/123 (20%), Positives = 62/123 (50%), Gaps = 13/123 (10%)
Query: 94 FLLSASLNSFLVACVILVVILLTLELLIDIKLLQFSSAFQFAGVIHWISLVILSVFFSET 153
F++S F++A + L ++L ++ + + +++ ++ +++V S+F E
Sbjct: 1467 FVVSPPFEYFIMAMIALNTVVLMMKF--------YDAPYEYELMLKCLNIVFTSMFSMEC 1518
Query: 154 VLRIVVLGIWDYIENKIEVFDGAVIILSLAPMVASTVANGPRSPWDAISLIIMLRIWRVK 213
VL+I+ G+ +Y + VFD ++ S+ ++ + +A + + LR++R
Sbjct: 1519 VLKIIAFGVLNYFRDAWNVFDFVTVLGSITDILVTEIAE-----TNNFINLSFLRLFRAA 1573
Query: 214 RVI 216
R+I
Sbjct: 1574 RLI 1576
Score = 37.0 bits (84), Expect = 0.045
Identities = 25/107 (23%), Positives = 51/107 (47%), Gaps = 4/107 (3%)
Query: 108 VILVVILLTLELLIDIKLLQFSSAFQFAGVIHWISLVILSVFFSETVLRIVVLGIWDYIE 167
V+ VV L TL + ++ ++ + +++ V L +F +E L++ LG Y
Sbjct: 488 VLCVVALNTL----CVAMVHYNQPRRLTTTLYFAEFVFLGLFLTEMSLKMYGLGPRSYFR 543
Query: 168 NKIEVFDGAVIILSLAPMVASTVANGPRSPWDAISLIIMLRIWRVKR 214
+ FD VI+ S+ +V + + G + + +LRI++V +
Sbjct: 544 SSFNCFDFGVIVGSVFEVVWAAIKPGSSFGISVLRALRLLRIFKVTK 590
>gi|93141214 sodium channel, voltage-gated, type II, alpha isoform 2
[Homo sapiens]
Length = 2005
Score = 42.0 bits (97), Expect = 0.001
Identities = 43/211 (20%), Positives = 93/211 (44%), Gaps = 26/211 (12%)
Query: 17 EGGISEVEIISQQVDEETKSIAPVQLVNFAYRDLPLAAVDLSTAGSQLLSNLDEDYQREG 76
EG +E EI ++ S+ ++ R + +A++ +T + L+E Q+
Sbjct: 672 EGTTTETEIRKRRSSSYHVSMDLLEDPTSRQRAMSIASILTNT-----MEELEESRQKCP 726
Query: 77 SNWLK--------PCCGKRAAVWQVFLLSASLNSFLVACVILVVILLTLELLIDIKLLQF 128
W K CC V + L ++ F+ + + ++L TL + ++ +
Sbjct: 727 PCWYKFANMCLIWDCCKPWLKVKHLVNLVV-MDPFVDLAITICIVLNTLFMAME----HY 781
Query: 129 SSAFQFAGVIHWISLVILSVFFSETVLRIVVLGIWDYIENKIEVFDGAVIILSLAPMVAS 188
QF+ V+ +LV +F +E L+I+ + + Y + +FDG ++ LSL + +
Sbjct: 782 PMTEQFSSVLSVGNLVFTGIFTAEMFLKIIAMDPYYYFQEGWNIFDGFIVSLSLMELGLA 841
Query: 189 TVANGPRSPWDAISLIIMLRIWRVKRVIDAY 219
V + +S++ R+ RV ++ ++
Sbjct: 842 NV--------EGLSVLRSFRLLRVFKLAKSW 864
>gi|93141212 sodium channel, voltage-gated, type II, alpha isoform 1
[Homo sapiens]
Length = 2005
Score = 42.0 bits (97), Expect = 0.001
Identities = 43/211 (20%), Positives = 93/211 (44%), Gaps = 26/211 (12%)
Query: 17 EGGISEVEIISQQVDEETKSIAPVQLVNFAYRDLPLAAVDLSTAGSQLLSNLDEDYQREG 76
EG +E EI ++ S+ ++ R + +A++ +T + L+E Q+
Sbjct: 672 EGTTTETEIRKRRSSSYHVSMDLLEDPTSRQRAMSIASILTNT-----MEELEESRQKCP 726
Query: 77 SNWLK--------PCCGKRAAVWQVFLLSASLNSFLVACVILVVILLTLELLIDIKLLQF 128
W K CC V + L ++ F+ + + ++L TL + ++ +
Sbjct: 727 PCWYKFANMCLIWDCCKPWLKVKHLVNLVV-MDPFVDLAITICIVLNTLFMAME----HY 781
Query: 129 SSAFQFAGVIHWISLVILSVFFSETVLRIVVLGIWDYIENKIEVFDGAVIILSLAPMVAS 188
QF+ V+ +LV +F +E L+I+ + + Y + +FDG ++ LSL + +
Sbjct: 782 PMTEQFSSVLSVGNLVFTGIFTAEMFLKIIAMDPYYYFQEGWNIFDGFIVSLSLMELGLA 841
Query: 189 TVANGPRSPWDAISLIIMLRIWRVKRVIDAY 219
V + +S++ R+ RV ++ ++
Sbjct: 842 NV--------EGLSVLRSFRLLRVFKLAKSW 864
>gi|93141210 sodium channel, voltage-gated, type II, alpha isoform 1
[Homo sapiens]
Length = 2005
Score = 42.0 bits (97), Expect = 0.001
Identities = 43/211 (20%), Positives = 93/211 (44%), Gaps = 26/211 (12%)
Query: 17 EGGISEVEIISQQVDEETKSIAPVQLVNFAYRDLPLAAVDLSTAGSQLLSNLDEDYQREG 76
EG +E EI ++ S+ ++ R + +A++ +T + L+E Q+
Sbjct: 672 EGTTTETEIRKRRSSSYHVSMDLLEDPTSRQRAMSIASILTNT-----MEELEESRQKCP 726
Query: 77 SNWLK--------PCCGKRAAVWQVFLLSASLNSFLVACVILVVILLTLELLIDIKLLQF 128
W K CC V + L ++ F+ + + ++L TL + ++ +
Sbjct: 727 PCWYKFANMCLIWDCCKPWLKVKHLVNLVV-MDPFVDLAITICIVLNTLFMAME----HY 781
Query: 129 SSAFQFAGVIHWISLVILSVFFSETVLRIVVLGIWDYIENKIEVFDGAVIILSLAPMVAS 188
QF+ V+ +LV +F +E L+I+ + + Y + +FDG ++ LSL + +
Sbjct: 782 PMTEQFSSVLSVGNLVFTGIFTAEMFLKIIAMDPYYYFQEGWNIFDGFIVSLSLMELGLA 841
Query: 189 TVANGPRSPWDAISLIIMLRIWRVKRVIDAY 219
V + +S++ R+ RV ++ ++
Sbjct: 842 NV--------EGLSVLRSFRLLRVFKLAKSW 864
>gi|111378393 sodium channel, voltage-gated, type VII, alpha [Homo
sapiens]
Length = 1682
Score = 41.6 bits (96), Expect = 0.002
Identities = 30/131 (22%), Positives = 60/131 (45%), Gaps = 13/131 (9%)
Query: 82 PCCGKRAAVWQVFLLSASLNSFLVACVILVVILLTLELLIDIKLLQFSSAFQFAGVIHWI 141
PC K +++ + FL+ C+IL V LTLE + + Q +++
Sbjct: 489 PCWLKLKEFVHRIIMAPFTDLFLIICIILNVCFLTLE--------HYPMSKQTNTLLNIG 540
Query: 142 SLVILSVFFSETVLRIVVLGIWDYIENKIEVFDGAVIILSLAPMVASTVANGPRSPWDAI 201
+LV + +F +E + +I+ + + Y + +FD ++ L + + VA +
Sbjct: 541 NLVFIGIFTAEMIFKIIAMHPYGYFQVGWNIFDSMIVFHGLIELCLANVAG-----MALL 595
Query: 202 SLIIMLRIWRV 212
L MLRI+++
Sbjct: 596 RLFRMLRIFKL 606
Score = 37.0 bits (84), Expect = 0.045
Identities = 26/146 (17%), Positives = 64/146 (43%), Gaps = 11/146 (7%)
Query: 92 QVFLLSASLNSFLVACVILVVILLTLELLIDIKLLQFSSAFQFAGVIHWISLVILSVFFS 151
Q F+ + V++++ + ++ID + + Q + ++WI+ + + ++
Sbjct: 1241 QGFIFDVVTSQAFNVIVMVLICFQAIAMMIDTDV----QSLQMSIALYWINSIFVMLYTM 1296
Query: 152 ETVLRIVVLGIWDYIENKIEVFDGAVIILSLAPMVASTVANGPRSPWDAISLII------ 205
E +L+++ + Y +FD V+I S+ + P + LI+
Sbjct: 1297 ECILKLIAFRCF-YFTIAWNIFDFMVVIFSITGLCLPMTVGSYLVPPSLVQLILLSRIIH 1355
Query: 206 MLRIWRVKRVIDAYVLPVKLEMEMVI 231
MLR+ + +V +LP+ L + ++
Sbjct: 1356 MLRLGKGPKVFHNLMLPLMLSLPALL 1381
>gi|93587342 voltage-gated sodium channel type 4 alpha [Homo
sapiens]
Length = 1836
Score = 40.8 bits (94), Expect = 0.003
Identities = 30/171 (17%), Positives = 72/171 (42%), Gaps = 31/171 (18%)
Query: 62 SQLLSNLDEDYQREGSNWLKPCCGKRAAVWQ-------------VFLLSASLNSFLVACV 108
S + L+E +Q+ W K C + +W + ++ ++ + C+
Sbjct: 531 SDAMEELEEAHQKCPPWWYK--CAHKVLIWNCCAPWLKFKNIIHLIVMDPFVDLGITICI 588
Query: 109 ILVVILLTLELLIDIKLLQFSSAFQFAGVIHWISLVILSVFFSETVLRIVVLGIWDYIEN 168
+L + + +E + F V+ +LV +F +E VL+++ + ++Y +
Sbjct: 589 VLNTLFMAME--------HYPMTEHFDNVLTVGNLVFTGIFTAEMVLKLIAMDPYEYFQQ 640
Query: 169 KIEVFDGAVIILSLAPMVASTVANGPRSPWDAISLIIMLRIWRVKRVIDAY 219
+FD ++ LSL + + V +S++ R+ RV ++ ++
Sbjct: 641 GWNIFDSIIVTLSLVELGLANV--------QGLSVLRSFRLLRVFKLAKSW 683
>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
sapiens]
Length = 2168
Score = 40.4 bits (93), Expect = 0.004
Identities = 57/291 (19%), Positives = 109/291 (37%), Gaps = 57/291 (19%)
Query: 241 QDEQLERLTQICQE-----QGFEIRQLRAHLAQQDLDLAAEREAALQAPHVL-------S 288
++++ + T IC++ Q + +L + + + R A H L
Sbjct: 1321 KEDKKGKKTDICEDEDEGDQAASVEELEKQIEKLSKQQSQYRRKLFDASHSLRSVMFGQD 1380
Query: 289 QPRSRFKVL-----------EAGTWDEETAAESVVEELQPSQEATMKDDMNSYISQYYNG 337
+ R R+ +L E+G EE A E E+L+ ++ +K++M N
Sbjct: 1381 RYRRRYWILPQCGGIFVEGMESGEGLEEIAKER--EKLKKAESVQIKEEMFETSGDSLNC 1438
Query: 338 PSSDSGVPEPAVCMVTTAAIDIHQPNISSDLFSLDMPLKL-------------GGNGTSA 384
++D + + + + +P S L L K+ G NG +
Sbjct: 1439 SNTDHCEQKEDLKEKDNTNLFLQKPGSFSKLSKLLEVAKMPPESEVMTPKPNAGANGCTL 1498
Query: 385 TSESASRSSVTRAQSDSSQTLGSSMDCSTAREEPSSEPGPSPPPLPSQQQVEEATVQD-- 442
+ +++ + S+ QS ++Q+ D + SS PG PLP+ Q ++ T ++
Sbjct: 1499 SYQNSGKHSLGSVQSTATQSNVEKADSNNLFNTGSSGPGKFYSPLPNDQLLKTLTEKNRQ 1558
Query: 443 LLSSLSEDPC-----------------PSQKALDPAPLARPSPAGSAQTSP 476
S L PC P + +P P+P GS+ +P
Sbjct: 1559 WFSLLPRTPCDDTSLTHADMSTASLVTPQSQPPSKSPSPTPAPLGSSAQNP 1609
>gi|237512982 voltage-gated sodium channel type V alpha isoform f
[Homo sapiens]
Length = 1962
Score = 40.0 bits (92), Expect = 0.005
Identities = 38/177 (21%), Positives = 79/177 (44%), Gaps = 18/177 (10%)
Query: 48 RDLPLAAVDLSTAGSQLLSNLDEDYQREGSNWLKPCCGKRAAVWQVFLLSASLNSFLVAC 107
R L+AV + T+ L L+E + W + +R +W+ L S+ +
Sbjct: 659 RQRALSAVSVLTSA---LEELEESRHKCPPCWNR--LAQRYLIWECCPLWMSIKQGVKLV 713
Query: 108 VILVVILLTLELLIDIKLL-----QFSSAFQFAGVIHWISLVILSVFFSETVLRIVVLGI 162
V+ LT+ + I + L ++ +F ++ +LV +F +E +I+ L
Sbjct: 714 VMDPFTDLTITMCIVLNTLFMALEHYNMTSEFEEMLQVGNLVFTGIFTAEMTFKIIALDP 773
Query: 163 WDYIENKIEVFDGAVIILSLAPMVASTVANGPRSPWDAISLIIMLRIWRVKRVIDAY 219
+ Y + +FD ++ILSL + S ++N +S++ R+ RV ++ ++
Sbjct: 774 YYYFQQGWNIFDSIIVILSLMELGLSRMSN--------LSVLRSFRLLRVFKLAKSW 822
Score = 33.5 bits (75), Expect = 0.50
Identities = 21/76 (27%), Positives = 39/76 (51%), Gaps = 1/76 (1%)
Query: 141 ISLVILSVFFSETVLRIVVLGIWDYIENKIEVFDGAVIILSLAPMVASTVANGPRSPWDA 200
I+L+ +++F E ++++ L + Y N +FD V+ILS+ V S +
Sbjct: 1509 INLLFVAIFTGECIVKLAALRHY-YFTNSWNIFDFVVVILSIVGTVLSDIIQKYFFSPTL 1567
Query: 201 ISLIIMLRIWRVKRVI 216
+I + RI R+ R+I
Sbjct: 1568 FRVIRLARIGRILRLI 1583
>gi|237512980 voltage-gated sodium channel type V alpha isoform e
[Homo sapiens]
Length = 1983
Score = 40.0 bits (92), Expect = 0.005
Identities = 38/177 (21%), Positives = 79/177 (44%), Gaps = 18/177 (10%)
Query: 48 RDLPLAAVDLSTAGSQLLSNLDEDYQREGSNWLKPCCGKRAAVWQVFLLSASLNSFLVAC 107
R L+AV + T+ L L+E + W + +R +W+ L S+ +
Sbjct: 659 RQRALSAVSVLTSA---LEELEESRHKCPPCWNR--LAQRYLIWECCPLWMSIKQGVKLV 713
Query: 108 VILVVILLTLELLIDIKLL-----QFSSAFQFAGVIHWISLVILSVFFSETVLRIVVLGI 162
V+ LT+ + I + L ++ +F ++ +LV +F +E +I+ L
Sbjct: 714 VMDPFTDLTITMCIVLNTLFMALEHYNMTSEFEEMLQVGNLVFTGIFTAEMTFKIIALDP 773
Query: 163 WDYIENKIEVFDGAVIILSLAPMVASTVANGPRSPWDAISLIIMLRIWRVKRVIDAY 219
+ Y + +FD ++ILSL + S ++N +S++ R+ RV ++ ++
Sbjct: 774 YYYFQQGWNIFDSIIVILSLMELGLSRMSN--------LSVLRSFRLLRVFKLAKSW 822
>gi|37622907 voltage-gated sodium channel type V alpha isoform a
[Homo sapiens]
Length = 2016
Score = 40.0 bits (92), Expect = 0.005
Identities = 38/177 (21%), Positives = 79/177 (44%), Gaps = 18/177 (10%)
Query: 48 RDLPLAAVDLSTAGSQLLSNLDEDYQREGSNWLKPCCGKRAAVWQVFLLSASLNSFLVAC 107
R L+AV + T+ L L+E + W + +R +W+ L S+ +
Sbjct: 659 RQRALSAVSVLTSA---LEELEESRHKCPPCWNR--LAQRYLIWECCPLWMSIKQGVKLV 713
Query: 108 VILVVILLTLELLIDIKLL-----QFSSAFQFAGVIHWISLVILSVFFSETVLRIVVLGI 162
V+ LT+ + I + L ++ +F ++ +LV +F +E +I+ L
Sbjct: 714 VMDPFTDLTITMCIVLNTLFMALEHYNMTSEFEEMLQVGNLVFTGIFTAEMTFKIIALDP 773
Query: 163 WDYIENKIEVFDGAVIILSLAPMVASTVANGPRSPWDAISLIIMLRIWRVKRVIDAY 219
+ Y + +FD ++ILSL + S ++N +S++ R+ RV ++ ++
Sbjct: 774 YYYFQQGWNIFDSIIVILSLMELGLSRMSN--------LSVLRSFRLLRVFKLAKSW 822
Score = 33.5 bits (75), Expect = 0.50
Identities = 21/76 (27%), Positives = 39/76 (51%), Gaps = 1/76 (1%)
Query: 141 ISLVILSVFFSETVLRIVVLGIWDYIENKIEVFDGAVIILSLAPMVASTVANGPRSPWDA 200
I+L+ +++F E ++++ L + Y N +FD V+ILS+ V S +
Sbjct: 1563 INLLFVAIFTGECIVKLAALRHY-YFTNSWNIFDFVVVILSIVGTVLSDIIQKYFFSPTL 1621
Query: 201 ISLIIMLRIWRVKRVI 216
+I + RI R+ R+I
Sbjct: 1622 FRVIRLARIGRILRLI 1637
>gi|30089970 voltage-gated sodium channel type V alpha isoform b
[Homo sapiens]
Length = 2015
Score = 40.0 bits (92), Expect = 0.005
Identities = 38/177 (21%), Positives = 79/177 (44%), Gaps = 18/177 (10%)
Query: 48 RDLPLAAVDLSTAGSQLLSNLDEDYQREGSNWLKPCCGKRAAVWQVFLLSASLNSFLVAC 107
R L+AV + T+ L L+E + W + +R +W+ L S+ +
Sbjct: 659 RQRALSAVSVLTSA---LEELEESRHKCPPCWNR--LAQRYLIWECCPLWMSIKQGVKLV 713
Query: 108 VILVVILLTLELLIDIKLL-----QFSSAFQFAGVIHWISLVILSVFFSETVLRIVVLGI 162
V+ LT+ + I + L ++ +F ++ +LV +F +E +I+ L
Sbjct: 714 VMDPFTDLTITMCIVLNTLFMALEHYNMTSEFEEMLQVGNLVFTGIFTAEMTFKIIALDP 773
Query: 163 WDYIENKIEVFDGAVIILSLAPMVASTVANGPRSPWDAISLIIMLRIWRVKRVIDAY 219
+ Y + +FD ++ILSL + S ++N +S++ R+ RV ++ ++
Sbjct: 774 YYYFQQGWNIFDSIIVILSLMELGLSRMSN--------LSVLRSFRLLRVFKLAKSW 822
Score = 33.5 bits (75), Expect = 0.50
Identities = 21/76 (27%), Positives = 39/76 (51%), Gaps = 1/76 (1%)
Query: 141 ISLVILSVFFSETVLRIVVLGIWDYIENKIEVFDGAVIILSLAPMVASTVANGPRSPWDA 200
I+L+ +++F E ++++ L + Y N +FD V+ILS+ V S +
Sbjct: 1562 INLLFVAIFTGECIVKLAALRHY-YFTNSWNIFDFVVVILSIVGTVLSDIIQKYFFSPTL 1620
Query: 201 ISLIIMLRIWRVKRVI 216
+I + RI R+ R+I
Sbjct: 1621 FRVIRLARIGRILRLI 1636
>gi|150417969 voltage-gated sodium channel type V alpha isoform d
[Homo sapiens]
Length = 1998
Score = 40.0 bits (92), Expect = 0.005
Identities = 38/177 (21%), Positives = 79/177 (44%), Gaps = 18/177 (10%)
Query: 48 RDLPLAAVDLSTAGSQLLSNLDEDYQREGSNWLKPCCGKRAAVWQVFLLSASLNSFLVAC 107
R L+AV + T+ L L+E + W + +R +W+ L S+ +
Sbjct: 659 RQRALSAVSVLTSA---LEELEESRHKCPPCWNR--LAQRYLIWECCPLWMSIKQGVKLV 713
Query: 108 VILVVILLTLELLIDIKLL-----QFSSAFQFAGVIHWISLVILSVFFSETVLRIVVLGI 162
V+ LT+ + I + L ++ +F ++ +LV +F +E +I+ L
Sbjct: 714 VMDPFTDLTITMCIVLNTLFMALEHYNMTSEFEEMLQVGNLVFTGIFTAEMTFKIIALDP 773
Query: 163 WDYIENKIEVFDGAVIILSLAPMVASTVANGPRSPWDAISLIIMLRIWRVKRVIDAY 219
+ Y + +FD ++ILSL + S ++N +S++ R+ RV ++ ++
Sbjct: 774 YYYFQQGWNIFDSIIVILSLMELGLSRMSN--------LSVLRSFRLLRVFKLAKSW 822
Score = 33.5 bits (75), Expect = 0.50
Identities = 21/76 (27%), Positives = 39/76 (51%), Gaps = 1/76 (1%)
Query: 141 ISLVILSVFFSETVLRIVVLGIWDYIENKIEVFDGAVIILSLAPMVASTVANGPRSPWDA 200
I+L+ +++F E ++++ L + Y N +FD V+ILS+ V S +
Sbjct: 1545 INLLFVAIFTGECIVKLAALRHY-YFTNSWNIFDFVVVILSIVGTVLSDIIQKYFFSPTL 1603
Query: 201 ISLIIMLRIWRVKRVI 216
+I + RI R+ R+I
Sbjct: 1604 FRVIRLARIGRILRLI 1619
>gi|150417967 voltage-gated sodium channel type V alpha isoform c
[Homo sapiens]
Length = 2016
Score = 40.0 bits (92), Expect = 0.005
Identities = 38/177 (21%), Positives = 79/177 (44%), Gaps = 18/177 (10%)
Query: 48 RDLPLAAVDLSTAGSQLLSNLDEDYQREGSNWLKPCCGKRAAVWQVFLLSASLNSFLVAC 107
R L+AV + T+ L L+E + W + +R +W+ L S+ +
Sbjct: 659 RQRALSAVSVLTSA---LEELEESRHKCPPCWNR--LAQRYLIWECCPLWMSIKQGVKLV 713
Query: 108 VILVVILLTLELLIDIKLL-----QFSSAFQFAGVIHWISLVILSVFFSETVLRIVVLGI 162
V+ LT+ + I + L ++ +F ++ +LV +F +E +I+ L
Sbjct: 714 VMDPFTDLTITMCIVLNTLFMALEHYNMTSEFEEMLQVGNLVFTGIFTAEMTFKIIALDP 773
Query: 163 WDYIENKIEVFDGAVIILSLAPMVASTVANGPRSPWDAISLIIMLRIWRVKRVIDAY 219
+ Y + +FD ++ILSL + S ++N +S++ R+ RV ++ ++
Sbjct: 774 YYYFQQGWNIFDSIIVILSLMELGLSRMSN--------LSVLRSFRLLRVFKLAKSW 822
Score = 33.5 bits (75), Expect = 0.50
Identities = 21/76 (27%), Positives = 39/76 (51%), Gaps = 1/76 (1%)
Query: 141 ISLVILSVFFSETVLRIVVLGIWDYIENKIEVFDGAVIILSLAPMVASTVANGPRSPWDA 200
I+L+ +++F E ++++ L + Y N +FD V+ILS+ V S +
Sbjct: 1563 INLLFVAIFTGECIVKLAALRHY-YFTNSWNIFDFVVVILSIVGTVLSDIIQKYFFSPTL 1621
Query: 201 ISLIIMLRIWRVKRVI 216
+I + RI R+ R+I
Sbjct: 1622 FRVIRLARIGRILRLI 1637
>gi|20070163 voltage-dependent calcium channel alpha 1G subunit
isoform 1 [Homo sapiens]
Length = 2377
Score = 39.7 bits (91), Expect = 0.007
Identities = 22/90 (24%), Positives = 47/90 (52%), Gaps = 11/90 (12%)
Query: 142 SLVILSVFFSETVLRIVVLGIWDYIENKIEVFDGAVIILSLAPMVASTVANGPRSPWDAI 201
++V S+F E +L+++V G + YI+N +FDG ++++S+ +V
Sbjct: 779 NIVFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGG--------- 829
Query: 202 SLIIMLRIWRVKRVIDAYVLPVKLEMEMVI 231
+ +LR +R+ RV+ L+ ++V+
Sbjct: 830 --LSVLRTFRLMRVLKLVRFLPALQRQLVV 857
Score = 33.9 bits (76), Expect = 0.38
Identities = 20/78 (25%), Positives = 41/78 (52%), Gaps = 6/78 (7%)
Query: 144 VILSVFFSETVLRIVVLGIW-----DYIENKIEVFDGAVIILSLAPMVASTVANGPRSPW 198
+ +VF +E +++V LG W Y+ + V DG ++++S+ ++ S V++
Sbjct: 1316 IFTAVFLAEMTVKVVALG-WCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKIL 1374
Query: 199 DAISLIIMLRIWRVKRVI 216
+ ++ +LR R RVI
Sbjct: 1375 GMLRVLRLLRTLRPLRVI 1392
>gi|38505294 voltage-dependent calcium channel alpha 1G subunit
isoform 15 [Homo sapiens]
Length = 1555
Score = 39.7 bits (91), Expect = 0.007
Identities = 22/90 (24%), Positives = 47/90 (52%), Gaps = 11/90 (12%)
Query: 142 SLVILSVFFSETVLRIVVLGIWDYIENKIEVFDGAVIILSLAPMVASTVANGPRSPWDAI 201
++V S+F E +L+++V G + YI+N +FDG ++++S+ +V
Sbjct: 779 NIVFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGG--------- 829
Query: 202 SLIIMLRIWRVKRVIDAYVLPVKLEMEMVI 231
+ +LR +R+ RV+ L+ ++V+
Sbjct: 830 --LSVLRTFRLMRVLKLVRFLPALQRQLVV 857
Score = 33.9 bits (76), Expect = 0.38
Identities = 20/78 (25%), Positives = 41/78 (52%), Gaps = 6/78 (7%)
Query: 144 VILSVFFSETVLRIVVLGIW-----DYIENKIEVFDGAVIILSLAPMVASTVANGPRSPW 198
+ +VF +E +++V LG W Y+ + V DG ++++S+ ++ S V++
Sbjct: 1316 IFTAVFLAEMTVKVVALG-WCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKIL 1374
Query: 199 DAISLIIMLRIWRVKRVI 216
+ ++ +LR R RVI
Sbjct: 1375 GMLRVLRLLRTLRPLRVI 1392
>gi|38505292 voltage-dependent calcium channel alpha 1G subunit
isoform 3 [Homo sapiens]
Length = 2343
Score = 39.7 bits (91), Expect = 0.007
Identities = 22/90 (24%), Positives = 47/90 (52%), Gaps = 11/90 (12%)
Query: 142 SLVILSVFFSETVLRIVVLGIWDYIENKIEVFDGAVIILSLAPMVASTVANGPRSPWDAI 201
++V S+F E +L+++V G + YI+N +FDG ++++S+ +V
Sbjct: 779 NIVFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGG--------- 829
Query: 202 SLIIMLRIWRVKRVIDAYVLPVKLEMEMVI 231
+ +LR +R+ RV+ L+ ++V+
Sbjct: 830 --LSVLRTFRLMRVLKLVRFLPALQRQLVV 857
Score = 33.9 bits (76), Expect = 0.38
Identities = 20/78 (25%), Positives = 41/78 (52%), Gaps = 6/78 (7%)
Query: 144 VILSVFFSETVLRIVVLGIW-----DYIENKIEVFDGAVIILSLAPMVASTVANGPRSPW 198
+ +VF +E +++V LG W Y+ + V DG ++++S+ ++ S V++
Sbjct: 1293 IFTAVFLAEMTVKVVALG-WCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKIL 1351
Query: 199 DAISLIIMLRIWRVKRVI 216
+ ++ +LR R RVI
Sbjct: 1352 GMLRVLRLLRTLRPLRVI 1369
>gi|38505290 voltage-dependent calcium channel alpha 1G subunit
isoform 13 [Homo sapiens]
Length = 2243
Score = 39.7 bits (91), Expect = 0.007
Identities = 22/90 (24%), Positives = 47/90 (52%), Gaps = 11/90 (12%)
Query: 142 SLVILSVFFSETVLRIVVLGIWDYIENKIEVFDGAVIILSLAPMVASTVANGPRSPWDAI 201
++V S+F E +L+++V G + YI+N +FDG ++++S+ +V
Sbjct: 779 NIVFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGG--------- 829
Query: 202 SLIIMLRIWRVKRVIDAYVLPVKLEMEMVI 231
+ +LR +R+ RV+ L+ ++V+
Sbjct: 830 --LSVLRTFRLMRVLKLVRFLPALQRQLVV 857
Score = 33.9 bits (76), Expect = 0.38
Identities = 20/78 (25%), Positives = 41/78 (52%), Gaps = 6/78 (7%)
Query: 144 VILSVFFSETVLRIVVLGIW-----DYIENKIEVFDGAVIILSLAPMVASTVANGPRSPW 198
+ +VF +E +++V LG W Y+ + V DG ++++S+ ++ S V++
Sbjct: 1293 IFTAVFLAEMTVKVVALG-WCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKIL 1351
Query: 199 DAISLIIMLRIWRVKRVI 216
+ ++ +LR R RVI
Sbjct: 1352 GMLRVLRLLRTLRPLRVI 1369
>gi|38505288 voltage-dependent calcium channel alpha 1G subunit
isoform 12 [Homo sapiens]
Length = 2250
Score = 39.7 bits (91), Expect = 0.007
Identities = 22/90 (24%), Positives = 47/90 (52%), Gaps = 11/90 (12%)
Query: 142 SLVILSVFFSETVLRIVVLGIWDYIENKIEVFDGAVIILSLAPMVASTVANGPRSPWDAI 201
++V S+F E +L+++V G + YI+N +FDG ++++S+ +V
Sbjct: 779 NIVFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGG--------- 829
Query: 202 SLIIMLRIWRVKRVIDAYVLPVKLEMEMVI 231
+ +LR +R+ RV+ L+ ++V+
Sbjct: 830 --LSVLRTFRLMRVLKLVRFLPALQRQLVV 857
Score = 33.9 bits (76), Expect = 0.38
Identities = 20/78 (25%), Positives = 41/78 (52%), Gaps = 6/78 (7%)
Query: 144 VILSVFFSETVLRIVVLGIW-----DYIENKIEVFDGAVIILSLAPMVASTVANGPRSPW 198
+ +VF +E +++V LG W Y+ + V DG ++++S+ ++ S V++
Sbjct: 1293 IFTAVFLAEMTVKVVALG-WCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKIL 1351
Query: 199 DAISLIIMLRIWRVKRVI 216
+ ++ +LR R RVI
Sbjct: 1352 GMLRVLRLLRTLRPLRVI 1369
>gi|38505286 voltage-dependent calcium channel alpha 1G subunit
isoform 10 [Homo sapiens]
Length = 2266
Score = 39.7 bits (91), Expect = 0.007
Identities = 22/90 (24%), Positives = 47/90 (52%), Gaps = 11/90 (12%)
Query: 142 SLVILSVFFSETVLRIVVLGIWDYIENKIEVFDGAVIILSLAPMVASTVANGPRSPWDAI 201
++V S+F E +L+++V G + YI+N +FDG ++++S+ +V
Sbjct: 779 NIVFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGG--------- 829
Query: 202 SLIIMLRIWRVKRVIDAYVLPVKLEMEMVI 231
+ +LR +R+ RV+ L+ ++V+
Sbjct: 830 --LSVLRTFRLMRVLKLVRFLPALQRQLVV 857
Score = 33.9 bits (76), Expect = 0.38
Identities = 20/78 (25%), Positives = 41/78 (52%), Gaps = 6/78 (7%)
Query: 144 VILSVFFSETVLRIVVLGIW-----DYIENKIEVFDGAVIILSLAPMVASTVANGPRSPW 198
+ +VF +E +++V LG W Y+ + V DG ++++S+ ++ S V++
Sbjct: 1316 IFTAVFLAEMTVKVVALG-WCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKIL 1374
Query: 199 DAISLIIMLRIWRVKRVI 216
+ ++ +LR R RVI
Sbjct: 1375 GMLRVLRLLRTLRPLRVI 1392
>gi|38505284 voltage-dependent calcium channel alpha 1G subunit
isoform 4 [Homo sapiens]
Length = 2332
Score = 39.7 bits (91), Expect = 0.007
Identities = 22/90 (24%), Positives = 47/90 (52%), Gaps = 11/90 (12%)
Query: 142 SLVILSVFFSETVLRIVVLGIWDYIENKIEVFDGAVIILSLAPMVASTVANGPRSPWDAI 201
++V S+F E +L+++V G + YI+N +FDG ++++S+ +V
Sbjct: 779 NIVFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGG--------- 829
Query: 202 SLIIMLRIWRVKRVIDAYVLPVKLEMEMVI 231
+ +LR +R+ RV+ L+ ++V+
Sbjct: 830 --LSVLRTFRLMRVLKLVRFLPALQRQLVV 857
Score = 33.9 bits (76), Expect = 0.38
Identities = 20/78 (25%), Positives = 41/78 (52%), Gaps = 6/78 (7%)
Query: 144 VILSVFFSETVLRIVVLGIW-----DYIENKIEVFDGAVIILSLAPMVASTVANGPRSPW 198
+ +VF +E +++V LG W Y+ + V DG ++++S+ ++ S V++
Sbjct: 1316 IFTAVFLAEMTVKVVALG-WCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKIL 1374
Query: 199 DAISLIIMLRIWRVKRVI 216
+ ++ +LR R RVI
Sbjct: 1375 GMLRVLRLLRTLRPLRVI 1392
>gi|38505282 voltage-dependent calcium channel alpha 1G subunit
isoform 8 [Homo sapiens]
Length = 2284
Score = 39.7 bits (91), Expect = 0.007
Identities = 22/90 (24%), Positives = 47/90 (52%), Gaps = 11/90 (12%)
Query: 142 SLVILSVFFSETVLRIVVLGIWDYIENKIEVFDGAVIILSLAPMVASTVANGPRSPWDAI 201
++V S+F E +L+++V G + YI+N +FDG ++++S+ +V
Sbjct: 779 NIVFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGG--------- 829
Query: 202 SLIIMLRIWRVKRVIDAYVLPVKLEMEMVI 231
+ +LR +R+ RV+ L+ ++V+
Sbjct: 830 --LSVLRTFRLMRVLKLVRFLPALQRQLVV 857
Score = 33.9 bits (76), Expect = 0.38
Identities = 20/78 (25%), Positives = 41/78 (52%), Gaps = 6/78 (7%)
Query: 144 VILSVFFSETVLRIVVLGIW-----DYIENKIEVFDGAVIILSLAPMVASTVANGPRSPW 198
+ +VF +E +++V LG W Y+ + V DG ++++S+ ++ S V++
Sbjct: 1316 IFTAVFLAEMTVKVVALG-WCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKIL 1374
Query: 199 DAISLIIMLRIWRVKRVI 216
+ ++ +LR R RVI
Sbjct: 1375 GMLRVLRLLRTLRPLRVI 1392
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.130 0.371
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,898,802
Number of Sequences: 37866
Number of extensions: 954154
Number of successful extensions: 9590
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 139
Number of HSP's successfully gapped in prelim test: 423
Number of HSP's that attempted gapping in prelim test: 8128
Number of HSP's gapped (non-prelim): 1683
length of query: 531
length of database: 18,247,518
effective HSP length: 107
effective length of query: 424
effective length of database: 14,195,856
effective search space: 6019042944
effective search space used: 6019042944
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.