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Search of human proteins with 118197272
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|118197272 ATG2 autophagy related 2 homolog B [Homo sapiens]
(2078 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|118197272 ATG2 autophagy related 2 homolog B [Homo sapiens] 4171 0.0
gi|239047271 autophagy related 2A [Homo sapiens] 1457 0.0
gi|42544121 vacuolar protein sorting 13C protein isoform 1A [Hom... 52 8e-06
gi|66348091 vacuolar protein sorting 13C protein isoform 1B [Hom... 52 8e-06
gi|54607141 vacuolar protein sorting 13D isoform 2 [Homo sapiens] 49 5e-05
gi|54607139 vacuolar protein sorting 13D isoform 1 [Homo sapiens] 49 5e-05
gi|66347845 vacuolar protein sorting 13C protein isoform 2B [Hom... 44 0.001
gi|66347828 vacuolar protein sorting 13C protein isoform 2A [Hom... 44 0.001
gi|15619008 vacuolar protein sorting 13A isoform B [Homo sapiens] 43 0.003
gi|66346676 vacuolar protein sorting 13A isoform D [Homo sapiens] 43 0.003
gi|66346674 vacuolar protein sorting 13A isoform A [Homo sapiens] 43 0.003
gi|66346672 vacuolar protein sorting 13A isoform C [Homo sapiens] 43 0.003
gi|134152667 ICBP90 binding protein 1 [Homo sapiens] 35 0.77
gi|122937434 Rho-guanine nucleotide exchange factor [Homo sapiens] 34 1.3
gi|55749659 UHRF1 (ICBP90) binding protein 1-like isoform b [Hom... 34 1.3
gi|55749644 UHRF1 (ICBP90) binding protein 1-like isoform a [Hom... 34 1.3
gi|41281453 serine/threonine kinase 2 [Homo sapiens] 33 2.2
gi|51972208 leucine, glutamate and lysine rich 1 [Homo sapiens] 33 2.9
gi|83716024 kinesin family member 21B [Homo sapiens] 33 3.8
gi|57242757 calsyntenin 1 isoform 1 [Homo sapiens] 32 5.0
gi|57242755 calsyntenin 1 isoform 2 [Homo sapiens] 32 5.0
gi|94536848 spermatogenesis-associated protein 7 isoform a [Homo... 32 6.5
gi|13994322 TBC1 domain family, member 10A [Homo sapiens] 32 6.5
gi|151101459 SAPS domain family, member 1 [Homo sapiens] 32 6.5
gi|5453629 dynactin 2 [Homo sapiens] 32 6.5
gi|239752523 PREDICTED: intestinal mucin-like, partial [Homo sap... 32 8.5
gi|197313732 pleckstrin homology-like domain, family B, member 2... 32 8.5
gi|197313730 pleckstrin homology-like domain, family B, member 2... 32 8.5
>gi|118197272 ATG2 autophagy related 2 homolog B [Homo sapiens]
Length = 2078
Score = 4171 bits (10818), Expect = 0.0
Identities = 2078/2078 (100%), Positives = 2078/2078 (100%)
Query: 1 MPWPFSESIKKRACRYLLQRYLGHFLQEKLSLEQLSLDLYQGTGSLAQVPLDKWCLNEIL 60
MPWPFSESIKKRACRYLLQRYLGHFLQEKLSLEQLSLDLYQGTGSLAQVPLDKWCLNEIL
Sbjct: 1 MPWPFSESIKKRACRYLLQRYLGHFLQEKLSLEQLSLDLYQGTGSLAQVPLDKWCLNEIL 60
Query: 61 ESADAPLEVTEGFIQSISLSVPWGSLLQDNCALEVRGLEMVFRPRPRPATGSEPMYWSSF 120
ESADAPLEVTEGFIQSISLSVPWGSLLQDNCALEVRGLEMVFRPRPRPATGSEPMYWSSF
Sbjct: 61 ESADAPLEVTEGFIQSISLSVPWGSLLQDNCALEVRGLEMVFRPRPRPATGSEPMYWSSF 120
Query: 121 MTSSMQLAKECLSQKLTDEQGEGSQPFEGLEKFAETIETVLRRVKVTFIDTVLRIEHVPE 180
MTSSMQLAKECLSQKLTDEQGEGSQPFEGLEKFAETIETVLRRVKVTFIDTVLRIEHVPE
Sbjct: 121 MTSSMQLAKECLSQKLTDEQGEGSQPFEGLEKFAETIETVLRRVKVTFIDTVLRIEHVPE 180
Query: 181 NSKTGTALEIRIERTVYCDETADESSGINVHQPTAFAHKLLQLSGVSLFWDEFSASAKSS 240
NSKTGTALEIRIERTVYCDETADESSGINVHQPTAFAHKLLQLSGVSLFWDEFSASAKSS
Sbjct: 181 NSKTGTALEIRIERTVYCDETADESSGINVHQPTAFAHKLLQLSGVSLFWDEFSASAKSS 240
Query: 241 PVCSTAPVETEPKLSPSWNPKIIYEPHPQLTRNLPEIAPSDPVQIGRLIGRLELSLTLKQ 300
PVCSTAPVETEPKLSPSWNPKIIYEPHPQLTRNLPEIAPSDPVQIGRLIGRLELSLTLKQ
Sbjct: 241 PVCSTAPVETEPKLSPSWNPKIIYEPHPQLTRNLPEIAPSDPVQIGRLIGRLELSLTLKQ 300
Query: 301 NEVLPGAKLDVDGQIDSIHLLLSPRQVHLLLDMLAAIAGPENSSKIGLANKDRKNRPMQQ 360
NEVLPGAKLDVDGQIDSIHLLLSPRQVHLLLDMLAAIAGPENSSKIGLANKDRKNRPMQQ
Sbjct: 301 NEVLPGAKLDVDGQIDSIHLLLSPRQVHLLLDMLAAIAGPENSSKIGLANKDRKNRPMQQ 360
Query: 361 EDEYRIQMELNRYYLRKDSLSVGVSSEQSFYETETARTPSSREEEVFFSMADMDMSHSLS 420
EDEYRIQMELNRYYLRKDSLSVGVSSEQSFYETETARTPSSREEEVFFSMADMDMSHSLS
Sbjct: 361 EDEYRIQMELNRYYLRKDSLSVGVSSEQSFYETETARTPSSREEEVFFSMADMDMSHSLS 420
Query: 421 SLPPLGDPPNMDLELSLTSTYTNTPAGSPLSATVLQPTWGEFLDHHKEQPVRGSTFPSNL 480
SLPPLGDPPNMDLELSLTSTYTNTPAGSPLSATVLQPTWGEFLDHHKEQPVRGSTFPSNL
Sbjct: 421 SLPPLGDPPNMDLELSLTSTYTNTPAGSPLSATVLQPTWGEFLDHHKEQPVRGSTFPSNL 480
Query: 481 VHPTPLQKTSLPSRSVSVDESRPELIFRLAVGTFSISVLHIDPLSPPETSQNLNPLTPMA 540
VHPTPLQKTSLPSRSVSVDESRPELIFRLAVGTFSISVLHIDPLSPPETSQNLNPLTPMA
Sbjct: 481 VHPTPLQKTSLPSRSVSVDESRPELIFRLAVGTFSISVLHIDPLSPPETSQNLNPLTPMA 540
Query: 541 VAFFTCIEKIDPARFSTEDFKSFRAVFAEACSHDHLRFIGTGIKVSYEQRQRSASRYFST 600
VAFFTCIEKIDPARFSTEDFKSFRAVFAEACSHDHLRFIGTGIKVSYEQRQRSASRYFST
Sbjct: 541 VAFFTCIEKIDPARFSTEDFKSFRAVFAEACSHDHLRFIGTGIKVSYEQRQRSASRYFST 600
Query: 601 DMSIGQMEFLECLFPTDFHSVPPHYTELLTFHSKEETGSHSPVCLQLHYKHSENRGPQGN 660
DMSIGQMEFLECLFPTDFHSVPPHYTELLTFHSKEETGSHSPVCLQLHYKHSENRGPQGN
Sbjct: 601 DMSIGQMEFLECLFPTDFHSVPPHYTELLTFHSKEETGSHSPVCLQLHYKHSENRGPQGN 660
Query: 661 QARLSSVPHKAELQIKLNPVCCELDISIVDRLNSLLQPQKLATVEMMASHMYTSYNKHIS 720
QARLSSVPHKAELQIKLNPVCCELDISIVDRLNSLLQPQKLATVEMMASHMYTSYNKHIS
Sbjct: 661 QARLSSVPHKAELQIKLNPVCCELDISIVDRLNSLLQPQKLATVEMMASHMYTSYNKHIS 720
Query: 721 LHKAFTEVFLDDSHSPANCRISVQVATPALNLSVRFPIPDLRSDQERGPWFKKSLQKEIL 780
LHKAFTEVFLDDSHSPANCRISVQVATPALNLSVRFPIPDLRSDQERGPWFKKSLQKEIL
Sbjct: 721 LHKAFTEVFLDDSHSPANCRISVQVATPALNLSVRFPIPDLRSDQERGPWFKKSLQKEIL 780
Query: 781 YLAFTDLEFKTEFIGGSTPEQIKLELTFRELIGSFQEEKGDPSIKFFHVSSGVDGDTTSS 840
YLAFTDLEFKTEFIGGSTPEQIKLELTFRELIGSFQEEKGDPSIKFFHVSSGVDGDTTSS
Sbjct: 781 YLAFTDLEFKTEFIGGSTPEQIKLELTFRELIGSFQEEKGDPSIKFFHVSSGVDGDTTSS 840
Query: 841 DDFDWPRIVLKINPPAMHSILERIAAEEEEENDGHYQEEEEGGAHSLKDVCDLRRPAPSP 900
DDFDWPRIVLKINPPAMHSILERIAAEEEEENDGHYQEEEEGGAHSLKDVCDLRRPAPSP
Sbjct: 841 DDFDWPRIVLKINPPAMHSILERIAAEEEEENDGHYQEEEEGGAHSLKDVCDLRRPAPSP 900
Query: 901 FSSRRVMFENEQMVMPGDPVEMTEFQDKAISNSHYVLELTLPNIYVTLPNKSFYEKLYNR 960
FSSRRVMFENEQMVMPGDPVEMTEFQDKAISNSHYVLELTLPNIYVTLPNKSFYEKLYNR
Sbjct: 901 FSSRRVMFENEQMVMPGDPVEMTEFQDKAISNSHYVLELTLPNIYVTLPNKSFYEKLYNR 960
Query: 961 IFNDLLLWEPTAPSPVETFENISYGIGLSVASQLINTFNKDSFSAFKSAVHYDEESGSEE 1020
IFNDLLLWEPTAPSPVETFENISYGIGLSVASQLINTFNKDSFSAFKSAVHYDEESGSEE
Sbjct: 961 IFNDLLLWEPTAPSPVETFENISYGIGLSVASQLINTFNKDSFSAFKSAVHYDEESGSEE 1020
Query: 1021 ETLQYFSTVDPNYRSRRKKKLDSQNKNSQSFLSVLLNINHGLIAVFTDVKQDNGDLLENK 1080
ETLQYFSTVDPNYRSRRKKKLDSQNKNSQSFLSVLLNINHGLIAVFTDVKQDNGDLLENK
Sbjct: 1021 ETLQYFSTVDPNYRSRRKKKLDSQNKNSQSFLSVLLNINHGLIAVFTDVKQDNGDLLENK 1080
Query: 1081 HGEFWLEFNSGSLFCVTKYEGFDDKHYICLHSSSFSLYHKGIVNGVILPTETRLPSSTRP 1140
HGEFWLEFNSGSLFCVTKYEGFDDKHYICLHSSSFSLYHKGIVNGVILPTETRLPSSTRP
Sbjct: 1081 HGEFWLEFNSGSLFCVTKYEGFDDKHYICLHSSSFSLYHKGIVNGVILPTETRLPSSTRP 1140
Query: 1141 HWLEPTIYSSEEDGLSKTSSDGVGGDSLNMLSVAVKILSDKSESNTKEFLIAVGLKGATL 1200
HWLEPTIYSSEEDGLSKTSSDGVGGDSLNMLSVAVKILSDKSESNTKEFLIAVGLKGATL
Sbjct: 1141 HWLEPTIYSSEEDGLSKTSSDGVGGDSLNMLSVAVKILSDKSESNTKEFLIAVGLKGATL 1200
Query: 1201 QHRMLPSGLSWHEQILYFLNIADEPVLGYNPPTSFTTFHVHLWSCALDYRPLYLPIRSLL 1260
QHRMLPSGLSWHEQILYFLNIADEPVLGYNPPTSFTTFHVHLWSCALDYRPLYLPIRSLL
Sbjct: 1201 QHRMLPSGLSWHEQILYFLNIADEPVLGYNPPTSFTTFHVHLWSCALDYRPLYLPIRSLL 1260
Query: 1261 TVETFSVSSSVALDKSSSTLRIILDEAALHLSDKCNTVTINLSRDYVRVMDMGLLELTIT 1320
TVETFSVSSSVALDKSSSTLRIILDEAALHLSDKCNTVTINLSRDYVRVMDMGLLELTIT
Sbjct: 1261 TVETFSVSSSVALDKSSSTLRIILDEAALHLSDKCNTVTINLSRDYVRVMDMGLLELTIT 1320
Query: 1321 AVKSDSDGEQTEPRFELHCSSDVVHIRTCSDSCAALMNLIQYIASYGDLQTPNKADMKPG 1380
AVKSDSDGEQTEPRFELHCSSDVVHIRTCSDSCAALMNLIQYIASYGDLQTPNKADMKPG
Sbjct: 1321 AVKSDSDGEQTEPRFELHCSSDVVHIRTCSDSCAALMNLIQYIASYGDLQTPNKADMKPG 1380
Query: 1381 AFQRRSKVDSSGRSSSRGPVLPEADQQMLRDLMSDAMEEIDMQQGTSSVKPQANGVLDEK 1440
AFQRRSKVDSSGRSSSRGPVLPEADQQMLRDLMSDAMEEIDMQQGTSSVKPQANGVLDEK
Sbjct: 1381 AFQRRSKVDSSGRSSSRGPVLPEADQQMLRDLMSDAMEEIDMQQGTSSVKPQANGVLDEK 1440
Query: 1441 SQIQEPCCSDLFLFPDESGNVSQESGPTYASFSHHFISDAMTGVPTENDDFCILFAPKAA 1500
SQIQEPCCSDLFLFPDESGNVSQESGPTYASFSHHFISDAMTGVPTENDDFCILFAPKAA
Sbjct: 1441 SQIQEPCCSDLFLFPDESGNVSQESGPTYASFSHHFISDAMTGVPTENDDFCILFAPKAA 1500
Query: 1501 MQEKEEEPVIKIMVDDAIVIRDNYFSLPVNKTDTSKAPLHFPIPVIRYVVKEVSLVWHLY 1560
MQEKEEEPVIKIMVDDAIVIRDNYFSLPVNKTDTSKAPLHFPIPVIRYVVKEVSLVWHLY
Sbjct: 1501 MQEKEEEPVIKIMVDDAIVIRDNYFSLPVNKTDTSKAPLHFPIPVIRYVVKEVSLVWHLY 1560
Query: 1561 GGKDFGTVPPTSPAKSYISPHSSPSHTPTRHGRNTVCGGKGRNHDFLMEIQLSKVKFQHE 1620
GGKDFGTVPPTSPAKSYISPHSSPSHTPTRHGRNTVCGGKGRNHDFLMEIQLSKVKFQHE
Sbjct: 1561 GGKDFGTVPPTSPAKSYISPHSSPSHTPTRHGRNTVCGGKGRNHDFLMEIQLSKVKFQHE 1620
Query: 1621 VYPPCKPDCDSSLSEHPVSRQVFIVQDLEIRDRLATSQMNKFLYLYCSKEMPRKAHSNML 1680
VYPPCKPDCDSSLSEHPVSRQVFIVQDLEIRDRLATSQMNKFLYLYCSKEMPRKAHSNML
Sbjct: 1621 VYPPCKPDCDSSLSEHPVSRQVFIVQDLEIRDRLATSQMNKFLYLYCSKEMPRKAHSNML 1680
Query: 1681 TVKALHVCPESGRSPQECCLRVSLMPLRLNIDQDALFFLKDFFTSLSAEVELQMTPDPEV 1740
TVKALHVCPESGRSPQECCLRVSLMPLRLNIDQDALFFLKDFFTSLSAEVELQMTPDPEV
Sbjct: 1681 TVKALHVCPESGRSPQECCLRVSLMPLRLNIDQDALFFLKDFFTSLSAEVELQMTPDPEV 1740
Query: 1741 KKSPGADVTCSLPRHLSTSKEPNLVISFSGPKQPSQNDSANSVEVVNGMEEKNFSAEEAS 1800
KKSPGADVTCSLPRHLSTSKEPNLVISFSGPKQPSQNDSANSVEVVNGMEEKNFSAEEAS
Sbjct: 1741 KKSPGADVTCSLPRHLSTSKEPNLVISFSGPKQPSQNDSANSVEVVNGMEEKNFSAEEAS 1800
Query: 1801 FRDQPVFFREFRFTSEVPIRLDYHGKHVSMDQGTLAGILIGLAQLNCSELKLKRLSYRHG 1860
FRDQPVFFREFRFTSEVPIRLDYHGKHVSMDQGTLAGILIGLAQLNCSELKLKRLSYRHG
Sbjct: 1801 FRDQPVFFREFRFTSEVPIRLDYHGKHVSMDQGTLAGILIGLAQLNCSELKLKRLSYRHG 1860
Query: 1861 LLGVDKLFSYAITEWLNDIKKNQLPGILGGVGPMHSLVQLVQGLKDLVWLPIEQYRKDGR 1920
LLGVDKLFSYAITEWLNDIKKNQLPGILGGVGPMHSLVQLVQGLKDLVWLPIEQYRKDGR
Sbjct: 1861 LLGVDKLFSYAITEWLNDIKKNQLPGILGGVGPMHSLVQLVQGLKDLVWLPIEQYRKDGR 1920
Query: 1921 IVRGFQRGAASFGTSTAMAALELTNRMVQTIQAAAETAYDMVSPGTLSIEPKKTKRFPHH 1980
IVRGFQRGAASFGTSTAMAALELTNRMVQTIQAAAETAYDMVSPGTLSIEPKKTKRFPHH
Sbjct: 1921 IVRGFQRGAASFGTSTAMAALELTNRMVQTIQAAAETAYDMVSPGTLSIEPKKTKRFPHH 1980
Query: 1981 RLAHQPVDLREGVAKAYSVVKEGITDTAQTIYETAAREHESRGVTGAVGEVLRQIPPAVV 2040
RLAHQPVDLREGVAKAYSVVKEGITDTAQTIYETAAREHESRGVTGAVGEVLRQIPPAVV
Sbjct: 1981 RLAHQPVDLREGVAKAYSVVKEGITDTAQTIYETAAREHESRGVTGAVGEVLRQIPPAVV 2040
Query: 2041 KPLIVATEATSNVLGGMRNQIRPDVRQDESQKWRHGDD 2078
KPLIVATEATSNVLGGMRNQIRPDVRQDESQKWRHGDD
Sbjct: 2041 KPLIVATEATSNVLGGMRNQIRPDVRQDESQKWRHGDD 2078
>gi|239047271 autophagy related 2A [Homo sapiens]
Length = 1938
Score = 1457 bits (3771), Expect = 0.0
Identities = 891/2112 (42%), Positives = 1219/2112 (57%), Gaps = 225/2112 (10%)
Query: 3 WPFSESIKKRACRYLLQRYLGHFLQEKLSLEQLSLDLYQGTGSLAQVPLDKWCLNEILES 62
WP+S +K+R CRYLL YLGHF QE LSL+QLSLDLY+G+ +L + L+ W +NE+LES
Sbjct: 6 WPWSNCVKERVCRYLLHHYLGHFFQEHLSLDQLSLDLYKGSVALRDIHLEIWSVNEVLES 65
Query: 63 ADAPLEVTEGFIQSISLSVPWGSLLQDNCALEVRGLEMVFRPRPRPATGS-EPMYWSSFM 121
++PLE+ EGF+ SI ++VPW +LL D+C + V GL++ +PR PA G+ + W+S M
Sbjct: 66 MESPLELVEGFVGSIEVAVPWAALLTDHCTVRVSGLQLTLQPRRGPAPGAADSQSWASCM 125
Query: 122 TSSMQLAKECLSQKLTDEQGEGSQPFEGLEKFAETIETVLRRVKVTFIDTVLRIEHVPEN 181
T+S+QLA+ECL L E E QP EGLE FA+TIETVLRR+KVTF+DTV+R+EH P +
Sbjct: 126 TTSLQLAQECLRDGLP-EPSEPPQPLEGLEMFAQTIETVLRRIKVTFLDTVVRVEHSPGD 184
Query: 182 SKTGTALEIRIERTVYCDETADESSG---INVHQPTAFAHKLLQLSGVSLFWDEFSASAK 238
+ G A+E+R++R YCDE + S ++VHQP AF HKLLQL+GV L ++E
Sbjct: 185 GERGVAVEVRVQRLEYCDEAVRDPSQAPPVDVHQPPAFLHKLLQLAGVRLHYEEL----- 239
Query: 239 SSPVCSTAPVETEPKLSPSWNPKIIYEPHPQLTRNLPEIAPSDPVQIGRLIGRLELSLTL 298
P + EP P P+QIG G +EL + L
Sbjct: 240 --------PAQEEP--------------------------PEPPLQIGSCSGYMELMVKL 265
Query: 299 KQNEVLPGAKLDVDGQIDSIHLLLSPRQVHLLLDMLAAIAGPENSSKIGLANKDRKNRPM 358
KQNE PG KL+V GQ+ S+HLLL+PRQ+ L ++L+A++ ++ GLA+K K+RP+
Sbjct: 266 KQNEAFPGPKLEVAGQLGSLHLLLTPRQLQQLQELLSAVSLTDHE---GLADKLNKSRPL 322
Query: 359 QQEDEYRIQMELNRYYLRKDSLSVGVSSEQSFYETETARTPSSREEEVFFSMADMDMSHS 418
ED + I+ +LN+ L G +E + T + ++FFSMA + S +
Sbjct: 323 GAEDLWLIEQDLNQ------QLQAGAVAEPLSPDPLTNPLLNLDNTDLFFSMAGLTSSVA 376
Query: 419 LSSLPPLGDPPNMDLELSLTSTYTNTPAGSPLSATVLQPTWGEFLDHHKEQPVRGSTFPS 478
S+L L ++ L S+ + A LSA P+
Sbjct: 377 -SALSELSLS-----DVDLASSVRSDMASRRLSA---------------------QAHPA 409
Query: 479 NLVHPTPLQKTSLPSRSVSVDESRPELIFRLAVGTFSISVLHIDPLS--PPETSQNLNPL 536
+ P PL +D RP+ + ++ +G ++++L S PP+
Sbjct: 410 GKMAPNPL-----------LDTMRPDSLLKMTLGGVTLTLLQTSAPSSGPPD-------- 450
Query: 537 TPMAVAFFTCIEKIDPARFSTEDFKSFRAVFAEACSHDHLRFIGTGIKVSYEQRQRSASR 596
+A FFT + F + DF R F AC H+R GT +++S+E R S R
Sbjct: 451 --LATHFFTEFDATKDGPFGSRDFHHLRPRFQRACPCSHVRLTGTAVQLSWELRTGSRGR 508
Query: 597 YF-STDMSIGQMEFLECLFPTDFHSVPPHYTELLTFHSKEETGSHSPVCLQLHYKHSENR 655
S ++ GQ+E LECL+P + P YTE+LTF + + + C L + R
Sbjct: 509 RTTSMEVHFGQLEVLECLWPRG--TSEPEYTEILTFPGTLGSQASARPCAHLRHTQILRR 566
Query: 656 GPQGNQARLSSVPHKAELQIKLNPVCCELDISIVDRLNSLLQPQKLATVEMMASHMYTSY 715
P+ R + +EL + L ++++ +DRL +LL +LATV
Sbjct: 567 VPKSRPRRSVACHCHSELALDLANFQADVELGALDRLAALL---RLATVP---------- 613
Query: 716 NKHISLHKAFTEVFLDDSHSPANCRISV-QVATPALNLSVRFPIPDLRSDQERGPWFKKS 774
A L PA + +V +++ P L +RFPI DLR + + PW ++
Sbjct: 614 --------AEPPAGLLTEPLPAMEQQTVFRLSAPRATLRLRFPIADLRPEPD--PWAGQA 663
Query: 775 LQKEILYLAFTDLEFKTEFIGG-STPEQIKLELTFRELIGSFQEEKGDPSIKFFHVSSGV 833
++ E L L ++ +F++E G P LELT +L G + E+ G P + VS +
Sbjct: 664 VRAEQLRLELSEPQFRSELSSGPGPPVPTHLELTCSDLHGIY-EDGGKPPVPCLRVSKAL 722
Query: 834 DGDTTSSDDFDWPRIVLKINPPAMHSILERIAAEEEEENDGHYQEEEEGGAHSLKDVCDL 893
D +T F P++V+ +NP + + E +A E+ EE + S++ C+L
Sbjct: 723 DPKSTGRKYF-LPQVVVTVNPQSSSTQWE-VAPEKGEELE-----------LSVESPCEL 769
Query: 894 RRPAPSPFSSRRVMFENEQMVMPGDPVEMTEFQDKAISNSHYVLELTLPNIYVTLPNKSF 953
R P PSPFSS+R M+E E+MV+PGDP EM FQ + ++ S LE+ LP++++ LP+K
Sbjct: 770 REPEPSPFSSKRTMYETEEMVIPGDPEEMRTFQSRTLALSRCSLEVILPSVHIFLPSKEV 829
Query: 954 YEKLYNRIFNDLLLWEPTAPSPVETFENISYGIGLSVASQLINTFNKDSFSAFKSAVHYD 1013
YE +YNRI NDLL+WEP P T + + G S + K SAFK A +D
Sbjct: 830 YESIYNRINNDLLMWEPADLLP--TPDPAAQPSGFPGPSGFWHDSFKMCKSAFKLANCFD 887
Query: 1014 --EESGSEEETLQYFSTVDPNYRSRRKKKLDSQNKNSQSFLSVLLNINHGLIAVFTDVKQ 1071
+S S++E +FS + ++ + + QS S L+ + G I + K
Sbjct: 888 LTPDSDSDDEDAHFFSVGASG--GPQAAAPEAPSLHLQSTFSTLVTVLKGRITALCETKD 945
Query: 1072 DNGDLLENKHGEFWLEFNSGSLFCVTKYEGFDDKHYICLHSSSFSLYHKGIVNGVILPTE 1131
+ G LE HGE L+ G+LF V++Y G Y CL + +LYH+ V+ LP+
Sbjct: 946 EGGKRLEAVHGELVLDMEHGTLFSVSQYCGQPGLGYFCLEAEKATLYHRAAVDDYPLPSH 1005
Query: 1132 TRLPSSTRPHWLEPTIYSSEEDGLSKTSSDGVG-GDSLNMLSVAVKILSDKSESNTKEFL 1190
LPS P L PTIY SEE + +S G G +MLS AV+I D + N KEFL
Sbjct: 1006 LDLPSFAPPAQLAPTIYPSEEGVTERGASGRKGQGRGPHMLSTAVRIHLDPHK-NVKEFL 1064
Query: 1191 IAVGLKGATLQHRMLPSGLSWHEQILYFLNIADEPVLGYNPPTSFTTFHVHLWSCALDYR 1250
+ + L ATL+H M SWH Q+L FL++ D+PVLGY PPT T H HL+SC++DYR
Sbjct: 1065 VTLRLHKATLRHYMALPEQSWHSQLLEFLDVLDDPVLGYLPPTVITILHTHLFSCSVDYR 1124
Query: 1251 PLYLPIRSLLTVETFSVSSSVALDKSSSTLRIILDEAALHLSDKCNTVTINLSRDYVRVM 1310
PLYLP+R L+T ETF++SS++ +D S+ LR ILD++AL+LSDKC T++L RDYV V+
Sbjct: 1125 PLYLPVRVLITAETFTLSSNIIMDTSTFLLRFILDDSALYLSDKCEVETLDLRRDYVCVL 1184
Query: 1311 DMGLLELTITAVKSDSDGEQTEPRFELHCSSDVVHIRTCSDSCAALMNLIQYIASYGDLQ 1370
D+ LLEL I K ++G+ ++P FEL CS++VVH+ +C+DSCA L+NL+QY+ S GDL
Sbjct: 1185 DVDLLELVIKTWKGSTEGKLSQPLFELRCSNNVVHVHSCADSCALLVNLLQYVMSTGDLH 1244
Query: 1371 TPNKADMKPGAFQRRSKVDSSGRSSSRGPV----LPEADQQML--RDLMSDAMEEIDMQQ 1424
P + S + +G+ S P P + ++ RDL +DA+ +D ++
Sbjct: 1245 PPPRPP---------SPTEIAGQKLSESPASLPSCPPVETALINQRDL-ADAL--LDTER 1292
Query: 1425 GTSSVKPQANGVLDEKSQIQEPCCSDLFLFPDESGNVSQESGP---------TYASFSHH 1475
+ + G L + S I ++LFP E S P + +
Sbjct: 1293 SLRELAQPSGGHLPQASPI------SVYLFPGERSGAPPPSPPVGGPAGSLGSCSEEKED 1346
Query: 1476 FISDAMTGVPTENDDFCILFAPKAAMQEKEEEPVIKIMVDDAIVIRDNYFSLPVNKTDTS 1535
+ G ++D+FCIL AP + ++ EPV+ + IV+RD YFS P+ TD
Sbjct: 1347 EREEEGDGDTLDSDEFCILDAPGLGIPPRDGEPVVTQLHPGPIVVRDGYFSRPIGSTDLL 1406
Query: 1536 KAPLHFPIPVIRYVVKEVSLVWHLYGGKDFGTVPPTSPAKSYISPHSSPSHT--PTRHGR 1593
+AP HFP+P R V++EVSLVWHLYGG+DFG P P SSPS P R
Sbjct: 1407 RAPAHFPVPSTRVVLREVSLVWHLYGGRDFGPHPGHRARTGLSGPRSSPSRCSGPNRPQN 1466
Query: 1594 N-TVCGGKGRNHDFLMEIQLSKVKFQHEVYP------PCKPDCDSSLSEHPVSRQVFIVQ 1646
+ GG GR H LMEIQLSKV FQHEVYP P P L E P+SRQVFIVQ
Sbjct: 1467 SWRTQGGSGRQHHVLMEIQLSKVSFQHEVYPAEPATGPAAP--SQELEERPLSRQVFIVQ 1524
Query: 1647 DLEIRDRLATSQMNKFLYLYCSKEMPRKAHSNMLTVKALHVCPESGRSPQECCLRVSLMP 1706
+LE+RDRLA+SQ+NKFLYL+ S+ MPR+AHSNMLT+KALHV P + ECCLRVSLMP
Sbjct: 1525 ELEVRDRLASSQINKFLYLHTSERMPRRAHSNMLTIKALHVAPTTNLGGPECCLRVSLMP 1584
Query: 1707 LRLNIDQDALFFLKDFFTSLSAEVELQMTPDPEVKKSPGADVTCSLPRHLSTSKEPNLVI 1766
LRLN+DQDALFFLKDFFTSL A + +P V P S P
Sbjct: 1585 LRLNVDQDALFFLKDFFTSLVAGI------NPVV------------PGETSAEARPETRA 1626
Query: 1767 SFSGPKQPSQNDSANSVEVVNGMEEKNFSAEEASFRDQPVFFREFRFTSEVPIRLDYHGK 1826
S P + A VE E + QP++FREFRFTSEVPI LDYHGK
Sbjct: 1627 QPSSPLE----GQAEGVETTGSQEAPGGGHSPSPPDQQPIYFREFRFTSEVPIWLDYHGK 1682
Query: 1827 HVSMDQ-GTLAGILIGLAQLNCSELKLKRLSYRHGLLGVDKLFSYAITEWLNDIKKNQLP 1885
HV+MDQ GT AG+LIGLAQLNCSELKLKRL RHGLLGVDK+ YA+ EWL DI+KNQLP
Sbjct: 1683 HVTMDQVGTFAGLLIGLAQLNCSELKLKRLCCRHGLLGVDKVLGYALNEWLQDIRKNQLP 1742
Query: 1886 GILGGVGPMHSLVQLVQGLKDLVWLPIEQYRKDGRIVRGFQRGAASFGTSTAMAALELTN 1945
G+LGGVGPMHS+VQL QG +DL+WLPIEQYRKDGR++RG QRGAASFG+STA AALEL+N
Sbjct: 1743 GLLGGVGPMHSVVQLFQGFRDLLWLPIEQYRKDGRLMRGLQRGAASFGSSTASAALELSN 1802
Query: 1946 RMVQTIQAAAETAYDMVSPG---TLSIEPKKTKRFPHHRLAHQPVDLREGVAKAYSVVKE 2002
R+VQ IQA AET YD++SP + S++ K++ R R QP DLREGVAKAY V+E
Sbjct: 1803 RLVQAIQATAETVYDILSPAAPVSRSLQDKRSAR--RLRRGQQPADLREGVAKAYDTVRE 1860
Query: 2003 GITDTAQTIYETAAREHESRGVTGAVGEVLRQIPPAVVKPLIVATEATSNVLGGMRNQIR 2062
GI DTAQTI + A+R HE +G+TGAVG V+RQ+PP VVKPLI+ATEATS++LGGMRNQI
Sbjct: 1861 GILDTAQTICDVASRGHEQKGLTGAVGGVIRQLPPTVVKPLILATEATSSLLGGMRNQIV 1920
Query: 2063 PDVRQDESQKWR 2074
PD +D + KWR
Sbjct: 1921 PDAHKDHALKWR 1932
>gi|42544121 vacuolar protein sorting 13C protein isoform 1A [Homo
sapiens]
Length = 3710
Score = 51.6 bits (122), Expect = 8e-06
Identities = 51/221 (23%), Positives = 103/221 (46%), Gaps = 19/221 (8%)
Query: 17 LLQRYLGHFLQEKLSLEQLSLDLYQGTGSLAQVPLDKWCLNEILESADAPLEVTEGFIQS 76
LL R+LG ++ E L+ QL L ++ G +L + + + L+E+ D P +V G I
Sbjct: 10 LLNRFLGDYV-ENLNKSQLKLGIWGGNVALDNLQIKENALSEL----DVPFKVKAGQIDK 64
Query: 77 ISLSVPWGSLLQDNCALEVRGLEMVFRPRPRPATGSEPMYWSSFMTSSMQLAKECLSQKL 136
++L +PW +L + + GL ++ P G+ Y + S+Q K+ ++
Sbjct: 65 LTLKIPWKNLYGEAVVATLEGLYLLVVP------GASIKYDAVKEEKSLQDVKQKELSRI 118
Query: 137 TD---EQGEGSQPFEG-LEKFAETIET-VLRRVKVTFIDTVLRIEHVPENSKTGTALEIR 191
+ + E +P E + F E + T V++ V+V D ++ E + K + +
Sbjct: 119 EEALQKAAEKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVT 178
Query: 192 IERTVYCDETADES-SGINVHQPTAFAHKLLQLSGVSLFWD 231
+ TA+E + +++ +KL++L +S +W+
Sbjct: 179 LGELSLL--TANEHWTPCILNEADKIIYKLIRLDSLSAYWN 217
>gi|66348091 vacuolar protein sorting 13C protein isoform 1B [Homo
sapiens]
Length = 3585
Score = 51.6 bits (122), Expect = 8e-06
Identities = 51/221 (23%), Positives = 103/221 (46%), Gaps = 19/221 (8%)
Query: 17 LLQRYLGHFLQEKLSLEQLSLDLYQGTGSLAQVPLDKWCLNEILESADAPLEVTEGFIQS 76
LL R+LG ++ E L+ QL L ++ G +L + + + L+E+ D P +V G I
Sbjct: 10 LLNRFLGDYV-ENLNKSQLKLGIWGGNVALDNLQIKENALSEL----DVPFKVKAGQIDK 64
Query: 77 ISLSVPWGSLLQDNCALEVRGLEMVFRPRPRPATGSEPMYWSSFMTSSMQLAKECLSQKL 136
++L +PW +L + + GL ++ P G+ Y + S+Q K+ ++
Sbjct: 65 LTLKIPWKNLYGEAVVATLEGLYLLVVP------GASIKYDAVKEEKSLQDVKQKELSRI 118
Query: 137 TD---EQGEGSQPFEG-LEKFAETIET-VLRRVKVTFIDTVLRIEHVPENSKTGTALEIR 191
+ + E +P E + F E + T V++ V+V D ++ E + K + +
Sbjct: 119 EEALQKAAEKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVT 178
Query: 192 IERTVYCDETADES-SGINVHQPTAFAHKLLQLSGVSLFWD 231
+ TA+E + +++ +KL++L +S +W+
Sbjct: 179 LGELSLL--TANEHWTPCILNEADKIIYKLIRLDSLSAYWN 217
>gi|54607141 vacuolar protein sorting 13D isoform 2 [Homo sapiens]
Length = 4363
Score = 48.9 bits (115), Expect = 5e-05
Identities = 48/217 (22%), Positives = 86/217 (39%), Gaps = 17/217 (7%)
Query: 16 YLLQRYLGHFLQEKLSLEQLSLDLYQGTGSLAQVPLDKWCLNEILESADAPLEVTEGFIQ 75
++L YLG ++ L+ +QLS+ L +G L +PL K L E+ + P EV GFI
Sbjct: 8 WVLNTYLGKYVNN-LNTDQLSVALLKGAVELENLPLKKDALKEL----ELPFEVKAGFIG 62
Query: 76 SISLSVPWGSLLQDNCALEVRGLEMVFRPRPRPATGSEPMYWSSFMTSSMQLAKECLSQK 135
++L +P+ D + + L ++ P E + + L +K
Sbjct: 63 KVTLQIPFYRPHVDPWVISISSLHLIGAPEKIQDFNDEKE--KLLERERKKALLQALEEK 120
Query: 136 -LTDEQGEGSQPFEGLEKFAETIETVLRRVKVTFIDTVLRIEHVPENSKTGTALEIRIER 194
D Q +G + + A + ++ +++ D LR E N A I
Sbjct: 121 WKNDRQQKGESYWYSVT--ASVVTRIVENIELKIQDVHLRFEDGVTNPSHPFAFGI---- 174
Query: 195 TVYCDETADESSGINVHQPTAFAHKLLQLSGVSLFWD 231
C + + +N K L ++ S++WD
Sbjct: 175 ---CIKNVSMQNAVNEPVQKLMRKKQLDVAEFSIYWD 208
>gi|54607139 vacuolar protein sorting 13D isoform 1 [Homo sapiens]
Length = 4388
Score = 48.9 bits (115), Expect = 5e-05
Identities = 48/217 (22%), Positives = 86/217 (39%), Gaps = 17/217 (7%)
Query: 16 YLLQRYLGHFLQEKLSLEQLSLDLYQGTGSLAQVPLDKWCLNEILESADAPLEVTEGFIQ 75
++L YLG ++ L+ +QLS+ L +G L +PL K L E+ + P EV GFI
Sbjct: 8 WVLNTYLGKYVNN-LNTDQLSVALLKGAVELENLPLKKDALKEL----ELPFEVKAGFIG 62
Query: 76 SISLSVPWGSLLQDNCALEVRGLEMVFRPRPRPATGSEPMYWSSFMTSSMQLAKECLSQK 135
++L +P+ D + + L ++ P E + + L +K
Sbjct: 63 KVTLQIPFYRPHVDPWVISISSLHLIGAPEKIQDFNDEKE--KLLERERKKALLQALEEK 120
Query: 136 -LTDEQGEGSQPFEGLEKFAETIETVLRRVKVTFIDTVLRIEHVPENSKTGTALEIRIER 194
D Q +G + + A + ++ +++ D LR E N A I
Sbjct: 121 WKNDRQQKGESYWYSVT--ASVVTRIVENIELKIQDVHLRFEDGVTNPSHPFAFGI---- 174
Query: 195 TVYCDETADESSGINVHQPTAFAHKLLQLSGVSLFWD 231
C + + +N K L ++ S++WD
Sbjct: 175 ---CIKNVSMQNAVNEPVQKLMRKKQLDVAEFSIYWD 208
>gi|66347845 vacuolar protein sorting 13C protein isoform 2B [Homo
sapiens]
Length = 3628
Score = 44.3 bits (103), Expect = 0.001
Identities = 26/88 (29%), Positives = 47/88 (53%), Gaps = 5/88 (5%)
Query: 17 LLQRYLGHFLQEKLSLEQLSLDLYQGTGSLAQVPLDKWCLNEILESADAPLEVTEGFIQS 76
LL R+LG ++ E L+ QL L ++ G +L + + + L+E+ D P +V G I
Sbjct: 10 LLNRFLGDYV-ENLNKSQLKLGIWGGNVALDNLQIKENALSEL----DVPFKVKAGQIDK 64
Query: 77 ISLSVPWGSLLQDNCALEVRGLEMVFRP 104
++L +PW +L + + GL ++ P
Sbjct: 65 LTLKIPWKNLYGEAVVATLEGLYLLVVP 92
>gi|66347828 vacuolar protein sorting 13C protein isoform 2A [Homo
sapiens]
Length = 3753
Score = 44.3 bits (103), Expect = 0.001
Identities = 26/88 (29%), Positives = 47/88 (53%), Gaps = 5/88 (5%)
Query: 17 LLQRYLGHFLQEKLSLEQLSLDLYQGTGSLAQVPLDKWCLNEILESADAPLEVTEGFIQS 76
LL R+LG ++ E L+ QL L ++ G +L + + + L+E+ D P +V G I
Sbjct: 10 LLNRFLGDYV-ENLNKSQLKLGIWGGNVALDNLQIKENALSEL----DVPFKVKAGQIDK 64
Query: 77 ISLSVPWGSLLQDNCALEVRGLEMVFRP 104
++L +PW +L + + GL ++ P
Sbjct: 65 LTLKIPWKNLYGEAVVATLEGLYLLVVP 92
>gi|15619008 vacuolar protein sorting 13A isoform B [Homo sapiens]
Length = 3095
Score = 43.1 bits (100), Expect = 0.003
Identities = 51/220 (23%), Positives = 99/220 (45%), Gaps = 17/220 (7%)
Query: 17 LLQRYLGHFLQEKLSLEQLSLDLYQGTGSLAQVPLDKWCLNEILESADAPLEVTEGFIQS 76
+L R+LG ++ + L QLSL +++G +L + + + L+++ D P +V G I +
Sbjct: 10 VLNRFLGDYVVD-LDTSQLSLGIWKGAVALKNLQIKENALSQL----DVPFKVKVGHIGN 64
Query: 77 ISLSVPWGSLLQDNCALEVRGLEMVFRPRPRPATGSEPM-YWSSFMTSSMQLAK--ECLS 133
+ L +PW +L + + ++ P R +P+ M + Q K E
Sbjct: 65 LKLIIPWKNLYTQPVEAVLEEIYLLIVPSSR--IKYDPLKEEKQLMEAKQQELKRIEEAK 122
Query: 134 QKLTDEQGEGSQPFEGLEKFAETIET-VLRRVKVTFIDTVLRIEHVPENSKTGTALEIRI 192
QK+ D+ E P E + FAE + T +++ ++V +R E N + I +
Sbjct: 123 QKVVDQ--EQHLP-EKQDTFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDKPLSFGISL 179
Query: 193 ERTVYCDETADESSGINVHQPT-AFAHKLLQLSGVSLFWD 231
+ +T D+ +H T KL++L + +W+
Sbjct: 180 QNLSM--QTTDQYWVPCLHDETEKLVRKLIRLDNLFAYWN 217
>gi|66346676 vacuolar protein sorting 13A isoform D [Homo sapiens]
Length = 3069
Score = 43.1 bits (100), Expect = 0.003
Identities = 51/220 (23%), Positives = 99/220 (45%), Gaps = 17/220 (7%)
Query: 17 LLQRYLGHFLQEKLSLEQLSLDLYQGTGSLAQVPLDKWCLNEILESADAPLEVTEGFIQS 76
+L R+LG ++ + L QLSL +++G +L + + + L+++ D P +V G I +
Sbjct: 10 VLNRFLGDYVVD-LDTSQLSLGIWKGAVALKNLQIKENALSQL----DVPFKVKVGHIGN 64
Query: 77 ISLSVPWGSLLQDNCALEVRGLEMVFRPRPRPATGSEPM-YWSSFMTSSMQLAK--ECLS 133
+ L +PW +L + + ++ P R +P+ M + Q K E
Sbjct: 65 LKLIIPWKNLYTQPVEAVLEEIYLLIVPSSR--IKYDPLKEEKQLMEAKQQELKRIEEAK 122
Query: 134 QKLTDEQGEGSQPFEGLEKFAETIET-VLRRVKVTFIDTVLRIEHVPENSKTGTALEIRI 192
QK+ D+ E P E + FAE + T +++ ++V +R E N + I +
Sbjct: 123 QKVVDQ--EQHLP-EKQDTFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDKPLSFGISL 179
Query: 193 ERTVYCDETADESSGINVHQPT-AFAHKLLQLSGVSLFWD 231
+ +T D+ +H T KL++L + +W+
Sbjct: 180 QNLSM--QTTDQYWVPCLHDETEKLVRKLIRLDNLFAYWN 217
>gi|66346674 vacuolar protein sorting 13A isoform A [Homo sapiens]
Length = 3174
Score = 43.1 bits (100), Expect = 0.003
Identities = 51/220 (23%), Positives = 99/220 (45%), Gaps = 17/220 (7%)
Query: 17 LLQRYLGHFLQEKLSLEQLSLDLYQGTGSLAQVPLDKWCLNEILESADAPLEVTEGFIQS 76
+L R+LG ++ + L QLSL +++G +L + + + L+++ D P +V G I +
Sbjct: 10 VLNRFLGDYVVD-LDTSQLSLGIWKGAVALKNLQIKENALSQL----DVPFKVKVGHIGN 64
Query: 77 ISLSVPWGSLLQDNCALEVRGLEMVFRPRPRPATGSEPM-YWSSFMTSSMQLAK--ECLS 133
+ L +PW +L + + ++ P R +P+ M + Q K E
Sbjct: 65 LKLIIPWKNLYTQPVEAVLEEIYLLIVPSSR--IKYDPLKEEKQLMEAKQQELKRIEEAK 122
Query: 134 QKLTDEQGEGSQPFEGLEKFAETIET-VLRRVKVTFIDTVLRIEHVPENSKTGTALEIRI 192
QK+ D+ E P E + FAE + T +++ ++V +R E N + I +
Sbjct: 123 QKVVDQ--EQHLP-EKQDTFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDKPLSFGISL 179
Query: 193 ERTVYCDETADESSGINVHQPT-AFAHKLLQLSGVSLFWD 231
+ +T D+ +H T KL++L + +W+
Sbjct: 180 QNLSM--QTTDQYWVPCLHDETEKLVRKLIRLDNLFAYWN 217
>gi|66346672 vacuolar protein sorting 13A isoform C [Homo sapiens]
Length = 3135
Score = 43.1 bits (100), Expect = 0.003
Identities = 51/220 (23%), Positives = 99/220 (45%), Gaps = 17/220 (7%)
Query: 17 LLQRYLGHFLQEKLSLEQLSLDLYQGTGSLAQVPLDKWCLNEILESADAPLEVTEGFIQS 76
+L R+LG ++ + L QLSL +++G +L + + + L+++ D P +V G I +
Sbjct: 10 VLNRFLGDYVVD-LDTSQLSLGIWKGAVALKNLQIKENALSQL----DVPFKVKVGHIGN 64
Query: 77 ISLSVPWGSLLQDNCALEVRGLEMVFRPRPRPATGSEPM-YWSSFMTSSMQLAK--ECLS 133
+ L +PW +L + + ++ P R +P+ M + Q K E
Sbjct: 65 LKLIIPWKNLYTQPVEAVLEEIYLLIVPSSR--IKYDPLKEEKQLMEAKQQELKRIEEAK 122
Query: 134 QKLTDEQGEGSQPFEGLEKFAETIET-VLRRVKVTFIDTVLRIEHVPENSKTGTALEIRI 192
QK+ D+ E P E + FAE + T +++ ++V +R E N + I +
Sbjct: 123 QKVVDQ--EQHLP-EKQDTFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDKPLSFGISL 179
Query: 193 ERTVYCDETADESSGINVHQPT-AFAHKLLQLSGVSLFWD 231
+ +T D+ +H T KL++L + +W+
Sbjct: 180 QNLSM--QTTDQYWVPCLHDETEKLVRKLIRLDNLFAYWN 217
>gi|134152667 ICBP90 binding protein 1 [Homo sapiens]
Length = 1440
Score = 35.0 bits (79), Expect = 0.77
Identities = 28/113 (24%), Positives = 51/113 (45%), Gaps = 9/113 (7%)
Query: 9 IKKRACRYLLQRYLGHFLQEKLSLEQLSLDLYQGTGSLAQVPLDKWCLNEILESADAPLE 68
IKK+ ++L + + LS ++++L +G G L + LD+ L +LE L
Sbjct: 5 IKKQILKHLSR------FTKNLSPDKINLSTLKGEGQLTNLELDEEVLQNVLE-LPTWLA 57
Query: 69 VTEGFIQSISLSVPWGSLLQDNCALEVRGLEMVFR--PRPRPATGSEPMYWSS 119
+T + S+ + W L L + +E+ + PRP G P+ +S
Sbjct: 58 ITRVYCNRASIRIQWTKLKTHPICLCLDKVEVEMKTCEDPRPPNGQSPIALAS 110
>gi|122937434 Rho-guanine nucleotide exchange factor [Homo sapiens]
Length = 1651
Score = 34.3 bits (77), Expect = 1.3
Identities = 36/160 (22%), Positives = 69/160 (43%), Gaps = 23/160 (14%)
Query: 272 RNLPEIAPSDPVQ----IGRLIGRLELSLTLKQNEVLPGAKLDVDGQIDSIHLLLSPRQV 327
RN P + S+ +Q + RL+ L+ +LT++ + + IH L+ +Q
Sbjct: 1362 RNFPGSSQSEIIQAIQNLTRLLYSLQAALTIQDSHI-------------EIHRLVLQQQE 1408
Query: 328 HLLLDMLAAIAGPENSSKIGLANKDRKNRPMQQEDEYRIQMELNRYYLRKDSLSVGVSSE 387
L L GP K A++ + + ++++Q E R+ R + ++
Sbjct: 1409 GLSLGHSILRGGPLQDQKSRDADRQHEELANVHQLQHQLQQEQRRWLRRCEQQQRAQATR 1468
Query: 388 QSFYETETARTPSSREEEVFFSMADMDM-----SHSLSSL 422
+S+ + E R S+EE + S ++D+ HSL L
Sbjct: 1469 ESWLQ-ERERECQSQEELLLRSRGELDLQLQEYQHSLERL 1507
>gi|55749659 UHRF1 (ICBP90) binding protein 1-like isoform b [Homo
sapiens]
Length = 522
Score = 34.3 bits (77), Expect = 1.3
Identities = 30/115 (26%), Positives = 51/115 (44%), Gaps = 13/115 (11%)
Query: 9 IKKRACRYLLQRYLGHFLQEKLSLEQLSLDLYQGTGSLAQVPLDKWCLNEILESADAP-- 66
IKK+ ++L + + LS ++++L +G G L + LD+ L +L D P
Sbjct: 5 IKKQILKHLSR------FTKNLSPDKINLSTLKGEGELKNLELDEEVLQNML---DLPTW 55
Query: 67 LEVTEGFIQSISLSVPWGSLLQDNCALEVRG--LEMVFRPRPRPATGSEPMYWSS 119
L + + F S+ +PW L L + +EM PR G P+ +S
Sbjct: 56 LAINKVFCNKASIRIPWTKLKTHPICLSLDKVIMEMSTCEEPRSPNGPSPIATAS 110
>gi|55749644 UHRF1 (ICBP90) binding protein 1-like isoform a [Homo
sapiens]
Length = 1464
Score = 34.3 bits (77), Expect = 1.3
Identities = 30/115 (26%), Positives = 51/115 (44%), Gaps = 13/115 (11%)
Query: 9 IKKRACRYLLQRYLGHFLQEKLSLEQLSLDLYQGTGSLAQVPLDKWCLNEILESADAP-- 66
IKK+ ++L + + LS ++++L +G G L + LD+ L +L D P
Sbjct: 5 IKKQILKHLSR------FTKNLSPDKINLSTLKGEGELKNLELDEEVLQNML---DLPTW 55
Query: 67 LEVTEGFIQSISLSVPWGSLLQDNCALEVRG--LEMVFRPRPRPATGSEPMYWSS 119
L + + F S+ +PW L L + +EM PR G P+ +S
Sbjct: 56 LAINKVFCNKASIRIPWTKLKTHPICLSLDKVIMEMSTCEEPRSPNGPSPIATAS 110
>gi|41281453 serine/threonine kinase 2 [Homo sapiens]
Length = 1235
Score = 33.5 bits (75), Expect = 2.2
Identities = 35/155 (22%), Positives = 60/155 (38%), Gaps = 29/155 (18%)
Query: 829 VSSGVDGDTTSSDDFDWPRIVLKINPPAMHSILERIAAEEEEENDGHYQEEEEGGAHSLK 888
+ VD T+S P + + N P I E A EE DG ++EEE +SL
Sbjct: 273 LEKNVDARWTTSQLLQHPFVTVDSNKPIRELIAEAKAEVTEEVEDGKEEDEEEETENSL- 331
Query: 889 DVCDLRRPAPSPFSSRRVMFENEQMVMPGDPVEMTEFQDKAISNSHYVLELTLPNIYVTL 948
P P S R + + ++ +S + +LE ++
Sbjct: 332 ---------PIPASKR-----------ASSDLSIASSEEDKLSQNACILE----SVSEKT 367
Query: 949 PNKSFYEKLYNRIFNDLLLWEPTAPSPVETFENIS 983
+ +KL ++I N+ +PT P + E+I+
Sbjct: 368 ERSNSEDKLNSKILNE----KPTTDEPEKAVEDIN 398
>gi|51972208 leucine, glutamate and lysine rich 1 [Homo sapiens]
Length = 388
Score = 33.1 bits (74), Expect = 2.9
Identities = 15/44 (34%), Positives = 26/44 (59%)
Query: 1007 KSAVHYDEESGSEEETLQYFSTVDPNYRSRRKKKLDSQNKNSQS 1050
KS Y EES S+E+ ++ + + SR KK++DS + S++
Sbjct: 177 KSHTRYTEESNSKEKEIENLKNLVAEFESRLKKEIDSNDSVSEN 220
>gi|83716024 kinesin family member 21B [Homo sapiens]
Length = 1624
Score = 32.7 bits (73), Expect = 3.8
Identities = 57/212 (26%), Positives = 80/212 (37%), Gaps = 40/212 (18%)
Query: 326 QVHLLLDMLA--AIAGPENSSKIGLANKDRKNRPMQQEDEYRIQMELNRYYLRKDSLSVG 383
Q HLLLD L A A PE + I Y +Q E N Y + +S
Sbjct: 1072 QNHLLLDALREKAEAHPELQALI-----------------YNVQQE-NGYASTDEEISE- 1112
Query: 384 VSSEQSFYETETARTPSSREEEVFFSMADMDMSHSLSSLPPLGDPPNM---DLELSLTST 440
SE SF ++ T + +S ++ F S + S LG P ++ ++ SL S
Sbjct: 1113 -FSEGSFSQSFTMKGSTSHDDFKFKSEPKLSAQMKAVSAECLGPPLDISTKNITKSLASL 1171
Query: 441 YTNTPAGSPLSATVLQPTWGEFLDHHKEQPVRGSTFPSNLVHPTPLQKTSLPSRSVSVDE 500
G S V P + + + P RGSTFP + +TS +R S D
Sbjct: 1172 VEIKEDGVGFS--VRDPYYRDRVSRTVSLPTRGSTFP----RQSRATETSPLTRRKSYDR 1225
Query: 501 SRPELIFRLAVGTFSISVLHIDPLSPPETSQN 532
+P S V P SPP +N
Sbjct: 1226 GQP---------IRSTDVGFTPPSSPPTRPRN 1248
>gi|57242757 calsyntenin 1 isoform 1 [Homo sapiens]
Length = 981
Score = 32.3 bits (72), Expect = 5.0
Identities = 23/78 (29%), Positives = 37/78 (47%), Gaps = 9/78 (11%)
Query: 806 LTFRELIGSFQEEKGDPSIKFFHVSSGVDGDTTSSDDFDWPRIVLKINPPAMHSILERIA 865
L F ++G F+ I+ H + D DT ++ DW L I M + ++ +
Sbjct: 871 LVFMIILGVFR-------IRAAHRRTMRDQDTGKENEMDWDDSALTITVNPMETYEDQHS 923
Query: 866 AEEEEENDGHYQEEEEGG 883
+EEEEE + +EE E G
Sbjct: 924 SEEEEEEE--EEEESEDG 939
>gi|57242755 calsyntenin 1 isoform 2 [Homo sapiens]
Length = 971
Score = 32.3 bits (72), Expect = 5.0
Identities = 23/78 (29%), Positives = 37/78 (47%), Gaps = 9/78 (11%)
Query: 806 LTFRELIGSFQEEKGDPSIKFFHVSSGVDGDTTSSDDFDWPRIVLKINPPAMHSILERIA 865
L F ++G F+ I+ H + D DT ++ DW L I M + ++ +
Sbjct: 861 LVFMIILGVFR-------IRAAHRRTMRDQDTGKENEMDWDDSALTITVNPMETYEDQHS 913
Query: 866 AEEEEENDGHYQEEEEGG 883
+EEEEE + +EE E G
Sbjct: 914 SEEEEEEE--EEEESEDG 929
>gi|94536848 spermatogenesis-associated protein 7 isoform a [Homo
sapiens]
Length = 599
Score = 32.0 bits (71), Expect = 6.5
Identities = 31/126 (24%), Positives = 58/126 (46%), Gaps = 34/126 (26%)
Query: 700 KLATVEMMASHMYTSYNKHISLHKAFTEVFLDDSHSPANCRISVQVATPALNLSVRFPIP 759
+L+T++++ +HM YNK +S A +C + V V+T S+++
Sbjct: 41 RLSTLQLVKNHMAVHYNKILSAKAA------------VDCSVPVSVST-----SIKY--- 80
Query: 760 DLRSDQERGPWFKKSLQKEILYLAFTDLEFKTEFIGGSTPEQIKLELTFRELIGSFQEEK 819
+DQ+R ++ L+KE LA + EFK T + + + L + Q+
Sbjct: 81 ---ADQQR----REKLKKE---LAQCEKEFKLT----KTAMRANYKNNSKSLFNTLQKPS 126
Query: 820 GDPSIK 825
G+P I+
Sbjct: 127 GEPQIE 132
>gi|13994322 TBC1 domain family, member 10A [Homo sapiens]
Length = 508
Score = 32.0 bits (71), Expect = 6.5
Identities = 24/91 (26%), Positives = 42/91 (46%), Gaps = 11/91 (12%)
Query: 17 LLQRYLGHFLQEKLSLEQLS----LDLYQGTGSLAQVPLDKWCLNEILESADAPLEVTEG 72
+ ++YL + EKL QL L Q +A L + + D L +TE
Sbjct: 222 ICEKYLPGYYSEKLEAIQLDGEILFSLLQKVSPVAHKHLSR-------QKIDPLLYMTEW 274
Query: 73 FIQSISLSVPWGSLLQDNCALEVRGLEMVFR 103
F+ + S ++PW S+L+ G++++FR
Sbjct: 275 FMCAFSRTLPWSSVLRVWDMFFCEGVKIIFR 305
>gi|151101459 SAPS domain family, member 1 [Homo sapiens]
Length = 881
Score = 32.0 bits (71), Expect = 6.5
Identities = 23/102 (22%), Positives = 43/102 (42%)
Query: 799 PEQIKLELTFRELIGSFQEEKGDPSIKFFHVSSGVDGDTTSSDDFDWPRIVLKINPPAMH 858
P LE+ +++ I F +++ + + S DG+ + R PP +
Sbjct: 604 PNANLLEICYKDRIQQFDDDEEEEDEEEAQGSGESDGEDGAWQGSQLARGARLGQPPGVR 663
Query: 859 SILERIAAEEEEENDGHYQEEEEGGAHSLKDVCDLRRPAPSP 900
S + +EEEE++ ++EE G + L P+P P
Sbjct: 664 SGGSTDSEDEEEEDEEEEEDEEGIGCAARGGATPLSYPSPGP 705
>gi|5453629 dynactin 2 [Homo sapiens]
Length = 406
Score = 32.0 bits (71), Expect = 6.5
Identities = 31/127 (24%), Positives = 55/127 (43%), Gaps = 14/127 (11%)
Query: 1941 LELTNRMVQTIQAAAETA-YDMVSPGTLSIEPKKTKRFPHHRLAHQPVDLREGVAKAYSV 1999
L+ ++R+ +T + E+ Y+M+ G + K+T + + RL H+ +L V K +
Sbjct: 72 LDFSDRIGKTKRTGYESGEYEMLGEG---LGVKETPQQKYQRLLHEVQELTTEVEKIKTT 128
Query: 2000 VKEGITDTAQT----------IYETAAREHESRGVTGAVGEVLRQIPPAVVKPLIVATEA 2049
VKE T+ T + + H + + L A+ K L++ EA
Sbjct: 129 VKESATEEKLTPVLLAKQLAALKQQLVASHLEKLLGPDAAINLTDPDGALAKRLLLQLEA 188
Query: 2050 TSNVLGG 2056
T N GG
Sbjct: 189 TKNSKGG 195
>gi|239752523 PREDICTED: intestinal mucin-like, partial [Homo
sapiens]
Length = 514
Score = 31.6 bits (70), Expect = 8.5
Identities = 39/153 (25%), Positives = 66/153 (43%), Gaps = 19/153 (12%)
Query: 416 SHSLSSLPPLGDPPNMDLELSLTSTYTNTPAGSPLSATVLQPTWGEFLDHHKEQPVRGS- 474
+++++S+ + PP S S+ T+ S LS+T++ T + + H R S
Sbjct: 59 TNTVTSMTTMTSPPTTTNSNSTLSSLTS----SILSSTLVPST--DMITSHTTNLTRSSP 112
Query: 475 ---TFPSNLVHPTPLQKTSLPSRSVS-VDESRPELIFRLAV-GTFSISVLHIDPLSPPET 529
T P+ + TP +T+ P+ S V S + + ++ GT S+ S P T
Sbjct: 113 LLATLPTTITRSTPTSETTYPTSPTSTVKGSTTSIRYSTSMTGTLSMET------SLPPT 166
Query: 530 SQNLNPLTPMAVAFFTCIEKIDPARFSTEDFKS 562
S +L P T A T + + ST F S
Sbjct: 167 SSSL-PTTETATTPTTNLVTTEITSHSTPSFSS 198
>gi|197313732 pleckstrin homology-like domain, family B, member 2
isoform a [Homo sapiens]
Length = 1253
Score = 31.6 bits (70), Expect = 8.5
Identities = 28/131 (21%), Positives = 60/131 (45%), Gaps = 11/131 (8%)
Query: 1316 ELTITAVKSDSDGEQTEPRFELHCSSDVVHIRTCSDSCAA-LMNLIQYIASYGDLQTPNK 1374
E T VK D++ E+ E EL+ S + C +S L ++ A D+++ +
Sbjct: 664 EKTKEKVKLDAEREKLERLQELY-SEQKTQLDNCPESMREQLQQQLKRDADLLDVESKHF 722
Query: 1375 ADMKPGAFQRRSKVDSSGRSSSRGPVLPEADQQMLRDLMSDAMEEIDMQQGTSSVKPQAN 1434
D++ + S++D + + QQ+LR++ + ++ S++K QAN
Sbjct: 723 EDLEFQQLEHESRLDEEKENLT---------QQLLREVAEYQRNIVSRKEKISALKKQAN 773
Query: 1435 GVLDEKSQIQE 1445
++ + + Q+
Sbjct: 774 HIVQQAQREQD 784
>gi|197313730 pleckstrin homology-like domain, family B, member 2
isoform a [Homo sapiens]
Length = 1253
Score = 31.6 bits (70), Expect = 8.5
Identities = 28/131 (21%), Positives = 60/131 (45%), Gaps = 11/131 (8%)
Query: 1316 ELTITAVKSDSDGEQTEPRFELHCSSDVVHIRTCSDSCAA-LMNLIQYIASYGDLQTPNK 1374
E T VK D++ E+ E EL+ S + C +S L ++ A D+++ +
Sbjct: 664 EKTKEKVKLDAEREKLERLQELY-SEQKTQLDNCPESMREQLQQQLKRDADLLDVESKHF 722
Query: 1375 ADMKPGAFQRRSKVDSSGRSSSRGPVLPEADQQMLRDLMSDAMEEIDMQQGTSSVKPQAN 1434
D++ + S++D + + QQ+LR++ + ++ S++K QAN
Sbjct: 723 EDLEFQQLEHESRLDEEKENLT---------QQLLREVAEYQRNIVSRKEKISALKKQAN 773
Query: 1435 GVLDEKSQIQE 1445
++ + + Q+
Sbjct: 774 HIVQQAQREQD 784
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.389
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 82,467,754
Number of Sequences: 37866
Number of extensions: 3969881
Number of successful extensions: 11942
Number of sequences better than 10.0: 28
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 11880
Number of HSP's gapped (non-prelim): 66
length of query: 2078
length of database: 18,247,518
effective HSP length: 118
effective length of query: 1960
effective length of database: 13,779,330
effective search space: 27007486800
effective search space used: 27007486800
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.