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Search of human proteins with 239751787
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239751787 PREDICTED: hypothetical protein XP_002348012 [Homo
sapiens]
(3003 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239751787 PREDICTED: hypothetical protein XP_002348012 [Homo ... 6398 0.0
gi|154146262 Fc fragment of IgG binding protein [Homo sapiens] 5465 0.0
gi|239757282 PREDICTED: similar to Fc fragment of IgG binding pr... 2930 0.0
gi|239757286 PREDICTED: similar to Fc fragment of IgG binding pr... 2726 0.0
gi|239757284 PREDICTED: similar to Fc fragment of IgG binding pr... 1158 0.0
gi|16554449 zonadhesin isoform 3 [Homo sapiens] 876 0.0
gi|27881494 zonadhesin isoform 6 [Homo sapiens] 856 0.0
gi|134268640 tectorin alpha precursor [Homo sapiens] 848 0.0
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens] 414 e-115
gi|169202626 PREDICTED: similar to mucin 5, partial [Homo sapiens] 412 e-114
gi|134031945 SCO-spondin [Homo sapiens] 406 e-112
gi|161019170 mucin 5AC [Homo sapiens] 400 e-111
gi|89191868 von Willebrand factor preproprotein [Homo sapiens] 383 e-105
gi|116284392 mucin 2 precursor [Homo sapiens] 345 5e-94
gi|239755901 PREDICTED: chromosome 12 open reading frame 64 [Hom... 319 2e-86
gi|239750386 PREDICTED: chromosome 12 open reading frame 64 [Hom... 319 2e-86
gi|239744688 PREDICTED: hypothetical protein LOC283310 [Homo sap... 319 2e-86
gi|151301154 mucin 6, gastric [Homo sapiens] 311 5e-84
gi|239755545 PREDICTED: otogelin isoform 1 [Homo sapiens] 310 2e-83
gi|239755543 PREDICTED: otogelin isoform 2 [Homo sapiens] 310 2e-83
gi|239749989 PREDICTED: otogelin isoform 2 [Homo sapiens] 310 2e-83
gi|239749987 PREDICTED: otogelin isoform 1 [Homo sapiens] 310 2e-83
gi|239744300 PREDICTED: otogelin isoform 2 [Homo sapiens] 310 2e-83
gi|239744298 PREDICTED: otogelin isoform 1 [Homo sapiens] 310 2e-83
gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo ... 241 6e-63
gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo ... 241 8e-63
gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens] 227 2e-58
gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens] 208 7e-53
gi|37693519 BMP-binding endothelial regulator precursor protein ... 185 7e-46
gi|239755776 PREDICTED: similar to Mucin-19 [Homo sapiens] 171 8e-42
>gi|239751787 PREDICTED: hypothetical protein XP_002348012 [Homo
sapiens]
Length = 3003
Score = 6398 bits (16600), Expect = 0.0
Identities = 3003/3003 (100%), Positives = 3003/3003 (100%)
Query: 1 MGALWSWWILWAGATLLWGLTQEASVDLKNTGREEFLTAFLQNYQLAYSKAYPRLLISSL 60
MGALWSWWILWAGATLLWGLTQEASVDLKNTGREEFLTAFLQNYQLAYSKAYPRLLISSL
Sbjct: 1 MGALWSWWILWAGATLLWGLTQEASVDLKNTGREEFLTAFLQNYQLAYSKAYPRLLISSL 60
Query: 61 SESPASVSILSQADNTSKKVTVRPGESVMVNISAKAEMIGSKIFQHAVVIHSDYAISVQA 120
SESPASVSILSQADNTSKKVTVRPGESVMVNISAKAEMIGSKIFQHAVVIHSDYAISVQA
Sbjct: 61 SESPASVSILSQADNTSKKVTVRPGESVMVNISAKAEMIGSKIFQHAVVIHSDYAISVQA 120
Query: 121 LNAKPDTAELTLLRPIQALGTEYFVLTPPGTSARNVKEFAVVAGAAGASVSVTLKGSVTF 180
LNAKPDTAELTLLRPIQALGTEYFVLTPPGTSARNVKEFAVVAGAAGASVSVTLKGSVTF
Sbjct: 121 LNAKPDTAELTLLRPIQALGTEYFVLTPPGTSARNVKEFAVVAGAAGASVSVTLKGSVTF 180
Query: 181 NGKFYPAGDVLRVTLQPYNVAQLQSSVDLSGSKVTASSPVAVLSGHSCAQKHTTCNHVVE 240
NGKFYPAGDVLRVTLQPYNVAQLQSSVDLSGSKVTASSPVAVLSGHSCAQKHTTCNHVVE
Sbjct: 181 NGKFYPAGDVLRVTLQPYNVAQLQSSVDLSGSKVTASSPVAVLSGHSCAQKHTTCNHVVE 240
Query: 241 QLLPTSAWGTHYVVPTLASQSRYDLAFVVASQATKLTYNHGGITGSRGLQAGDVVEFEVR 300
QLLPTSAWGTHYVVPTLASQSRYDLAFVVASQATKLTYNHGGITGSRGLQAGDVVEFEVR
Sbjct: 241 QLLPTSAWGTHYVVPTLASQSRYDLAFVVASQATKLTYNHGGITGSRGLQAGDVVEFEVR 300
Query: 301 PSWPLYLSANVGIQVLLFGTGAIRNEVTYDPYLVLIPDVAAYCPAYVVKSVPGCEGVALV 360
PSWPLYLSANVGIQVLLFGTGAIRNEVTYDPYLVLIPDVAAYCPAYVVKSVPGCEGVALV
Sbjct: 301 PSWPLYLSANVGIQVLLFGTGAIRNEVTYDPYLVLIPDVAAYCPAYVVKSVPGCEGVALV 360
Query: 361 VAQTKAISGLTIDGHAVGAKLTWEAVPGSEFSYAEVELGTADMIHTAEATTNLGLLTFGL 420
VAQTKAISGLTIDGHAVGAKLTWEAVPGSEFSYAEVELGTADMIHTAEATTNLGLLTFGL
Sbjct: 361 VAQTKAISGLTIDGHAVGAKLTWEAVPGSEFSYAEVELGTADMIHTAEATTNLGLLTFGL 420
Query: 421 AKAIGYATAADCGRTVLSPVEPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHY 480
AKAIGYATAADCGRTVLSPVEPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHY
Sbjct: 421 AKAIGYATAADCGRTVLSPVEPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHY 480
Query: 481 TTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSV 540
TTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSV
Sbjct: 481 TTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSV 540
Query: 541 SLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLP 600
SLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLP
Sbjct: 541 SLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLP 600
Query: 601 ARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPAC 660
ARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPAC
Sbjct: 601 ARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPAC 660
Query: 661 TPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSA 720
TPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSA
Sbjct: 661 TPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSA 720
Query: 721 YAQACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGC 780
YAQACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGC
Sbjct: 721 YAQACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGC 780
Query: 781 VCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQS 840
VCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQS
Sbjct: 781 VCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQS 840
Query: 841 CPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL 900
CPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL
Sbjct: 841 CPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL 900
Query: 901 PAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQV 960
PAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQV
Sbjct: 901 PAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQV 960
Query: 961 QVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGG 1020
QVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGG
Sbjct: 961 QVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGG 1020
Query: 1021 QAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHS 1080
QAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHS
Sbjct: 1021 QAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHS 1080
Query: 1081 KLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHS 1140
KLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHS
Sbjct: 1081 KLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHS 1140
Query: 1141 HYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPP 1200
HYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPP
Sbjct: 1141 HYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPP 1200
Query: 1201 GQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHY 1260
GQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHY
Sbjct: 1201 GQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHY 1260
Query: 1261 TTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTL 1320
TTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTL
Sbjct: 1261 TTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTL 1320
Query: 1321 RLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPG 1380
RLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPG
Sbjct: 1321 RLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPG 1380
Query: 1381 NYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSED 1440
NYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSED
Sbjct: 1381 NYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSED 1440
Query: 1441 CIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSI 1500
CIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSI
Sbjct: 1441 CIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSI 1500
Query: 1501 LCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQD 1560
LCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQD
Sbjct: 1501 LCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQD 1560
Query: 1561 GCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQ 1620
GCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQ
Sbjct: 1561 GCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQ 1620
Query: 1621 EHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPH 1680
EHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPH
Sbjct: 1621 EHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPH 1680
Query: 1681 YHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAAL 1740
YHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAAL
Sbjct: 1681 YHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAAL 1740
Query: 1741 GTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWR 1800
GTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWR
Sbjct: 1741 GTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWR 1800
Query: 1801 VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECR 1860
VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECR
Sbjct: 1801 VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECR 1860
Query: 1861 GSCPTCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDI 1920
GSCPTCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDI
Sbjct: 1861 GSCPTCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDI 1920
Query: 1921 LCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAV 1980
LCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAV
Sbjct: 1921 LCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAV 1980
Query: 1981 CEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGG 2040
CEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGG
Sbjct: 1981 CEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGG 2040
Query: 2041 GSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLL 2100
GSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLL
Sbjct: 2041 GSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLL 2100
Query: 2101 SAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFV 2160
SAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFV
Sbjct: 2101 SAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFV 2160
Query: 2161 ALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDP 2220
ALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDP
Sbjct: 2161 ALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDP 2220
Query: 2221 ADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAP 2280
ADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAP
Sbjct: 2221 ADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAP 2280
Query: 2281 CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCP 2340
CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCP
Sbjct: 2281 CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCP 2340
Query: 2341 AHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRY 2400
AHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRY
Sbjct: 2341 AHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRY 2400
Query: 2401 YPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANG 2460
YPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANG
Sbjct: 2401 YPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANG 2460
Query: 2461 GIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVS 2520
GIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVS
Sbjct: 2461 GIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVS 2520
Query: 2521 LAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRG 2580
LAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRG
Sbjct: 2521 LAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRG 2580
Query: 2581 RLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEE 2640
RLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEE
Sbjct: 2581 RLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEE 2640
Query: 2641 TAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAA 2700
TAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAA
Sbjct: 2641 TAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAA 2700
Query: 2701 CQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDR 2760
CQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDR
Sbjct: 2701 CQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDR 2760
Query: 2761 FLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCE 2820
FLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCE
Sbjct: 2761 FLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCE 2820
Query: 2821 VKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYRVVAE 2880
VKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYRVVAE
Sbjct: 2821 VKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYRVVAE 2880
Query: 2881 VQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDGSLLV 2940
VQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDGSLLV
Sbjct: 2881 VQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDGSLLV 2940
Query: 2941 RQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHDSQEKPAMEKWRAQDF 3000
RQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHDSQEKPAMEKWRAQDF
Sbjct: 2941 RQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHDSQEKPAMEKWRAQDF 3000
Query: 3001 SPW 3003
SPW
Sbjct: 3001 SPW 3003
>gi|154146262 Fc fragment of IgG binding protein [Homo sapiens]
Length = 5405
Score = 5465 bits (14176), Expect = 0.0
Identities = 2617/3062 (85%), Positives = 2730/3062 (89%), Gaps = 70/3062 (2%)
Query: 1 MGALWSWWILWAGATLLWGLTQEASVDLKNTGREEFLTAFLQNYQLAYSKAYPRLLISSL 60
MGALWSWWILWAGATLLWGLTQEASVDLKNTGREEFLTAFLQNYQLAYSKAYPRLLISSL
Sbjct: 1 MGALWSWWILWAGATLLWGLTQEASVDLKNTGREEFLTAFLQNYQLAYSKAYPRLLISSL 60
Query: 61 SESPASVSILSQADNTSKKVTVRPGESVMVNISAKAEMIGSKIFQHAVVIHSDYAISVQA 120
SESPASVSILSQADNTSKKVTVRPGESVMVNISAKAEMIGSKIFQHAVVIHSDYAISVQA
Sbjct: 61 SESPASVSILSQADNTSKKVTVRPGESVMVNISAKAEMIGSKIFQHAVVIHSDYAISVQA 120
Query: 121 LNAKPDTAELTLLRPIQALGTEYFVLTPPGTSARNVKEFAVVAGAAGASVSVTLKGSVTF 180
LNAKPDTAELTLLRPIQALGTEYFVLTPPGTSARNVKEFAVVAGAAGASVSVTLKGSVTF
Sbjct: 121 LNAKPDTAELTLLRPIQALGTEYFVLTPPGTSARNVKEFAVVAGAAGASVSVTLKGSVTF 180
Query: 181 NGKFYPAGDVLRVTLQPYNVAQLQSSVDLSGSKVTASSPVAVLSGHSCAQKHTTCNHVVE 240
NGKFYPAGDVLRVTLQPYNVAQLQSSVDLSGSKVTASSPVAVLSGHSCAQKHTTCNHVVE
Sbjct: 181 NGKFYPAGDVLRVTLQPYNVAQLQSSVDLSGSKVTASSPVAVLSGHSCAQKHTTCNHVVE 240
Query: 241 QLLPTSAWGTHYVVPTLASQSRYDLAFVVASQATKLTYNHGGITGSRGLQAGDVVEFEVR 300
QLLPTSAWGTHYVVPTLASQSRYDLAFVVASQATKLTYNHGGITGSRGLQAGDVVEFEVR
Sbjct: 241 QLLPTSAWGTHYVVPTLASQSRYDLAFVVASQATKLTYNHGGITGSRGLQAGDVVEFEVR 300
Query: 301 PSWPLYLSANVGIQVLLFGTGAIRNEVTYDPYLVLIPDVAAYCPAYVVKSVPGCEGVALV 360
PSWPLYLSANVGIQVLLFGTGAIRNEVTYDPYLVLIPDVAAYCPAYVVKSVPGCEGVALV
Sbjct: 301 PSWPLYLSANVGIQVLLFGTGAIRNEVTYDPYLVLIPDVAAYCPAYVVKSVPGCEGVALV 360
Query: 361 VAQTKAISGLTIDGHAVGAKLTWEAVPGSEFSYAEVELGTADMIHTAEATTNLGLLTFGL 420
VAQTKAISGLTIDGHAVGAKLTWEAVPGSEFSYAEVELGTADMIHTAEATTNLGLLTFGL
Sbjct: 361 VAQTKAISGLTIDGHAVGAKLTWEAVPGSEFSYAEVELGTADMIHTAEATTNLGLLTFGL 420
Query: 421 AKAIGYATAADCGRTVLSPVEPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHY 480
AKAIGYATAADCGRTVLSPVEPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHY
Sbjct: 421 AKAIGYATAADCGRTVLSPVEPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHY 480
Query: 481 TTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSV 540
TTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSV
Sbjct: 481 TTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSV 540
Query: 541 SLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLP 600
SLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLP
Sbjct: 541 SLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLP 600
Query: 601 ARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPAC 660
ARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPAC
Sbjct: 601 ARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPAC 660
Query: 661 TPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSA 720
TPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSA
Sbjct: 661 TPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSA 720
Query: 721 YAQACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGC 780
YAQACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGC
Sbjct: 721 YAQACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGC 780
Query: 781 VCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQS 840
VCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQS
Sbjct: 781 VCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQS 840
Query: 841 CPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL 900
CPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL
Sbjct: 841 CPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL 900
Query: 901 PAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQV 960
PAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQV
Sbjct: 901 PAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQV 960
Query: 961 QVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGG 1020
QVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGG
Sbjct: 961 QVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGG 1020
Query: 1021 QAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHS 1080
QAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHS
Sbjct: 1021 QAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHS 1080
Query: 1081 KLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHS 1140
KLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHS
Sbjct: 1081 KLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHS 1140
Query: 1141 HYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPP 1200
HYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPP
Sbjct: 1141 HYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPP 1200
Query: 1201 GQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHY 1260
GQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHY
Sbjct: 1201 GQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHY 1260
Query: 1261 TTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTL 1320
TTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTL
Sbjct: 1261 TTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTL 1320
Query: 1321 RLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPG 1380
RLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPG
Sbjct: 1321 RLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPG 1380
Query: 1381 NYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSED 1440
NYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSED
Sbjct: 1381 NYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSED 1440
Query: 1441 CIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSI 1500
CIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSI
Sbjct: 1441 CIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSI 1500
Query: 1501 LCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQD 1560
LCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQD
Sbjct: 1501 LCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQD 1560
Query: 1561 GCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQ 1620
GCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQ
Sbjct: 1561 GCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQ 1620
Query: 1621 EHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPH 1680
EHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPH
Sbjct: 1621 EHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPH 1680
Query: 1681 YHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAAL 1740
YHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAAL
Sbjct: 1681 YHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAAL 1740
Query: 1741 GTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWR 1800
GTNISIHKDEIGKVR VNGVLTALPVSVADGRISV QGASKALLVADFGLQVSYDWNWR
Sbjct: 1741 GTNISIHKDEIGKVR--VNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWR 1798
Query: 1801 VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECR 1860
VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECR
Sbjct: 1799 VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECR 1858
Query: 1861 GSCPTCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDI 1920
GSCPTCPEDRLEQYEGPGFCGPLA GTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDI
Sbjct: 1859 GSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDI 1918
Query: 1921 LCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAV 1980
LCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCG PCPASCPSPAPLTTPAV
Sbjct: 1919 LCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGSPCPASCPSPAPLTTPAV 1978
Query: 1981 CEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGG 2040
CEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGG
Sbjct: 1979 CEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGG 2038
Query: 2041 GSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLL 2100
GSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRF+FQGTCEYLL
Sbjct: 2039 GSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFNFQGTCEYLL 2098
Query: 2101 SAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFV 2160
SAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFV
Sbjct: 2099 SAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFV 2158
Query: 2161 ALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDP 2220
LPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYA SLCGLCGNYNQDP
Sbjct: 2159 TLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDP 2218
Query: 2221 ADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAP 2280
ADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAP
Sbjct: 2219 ADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAP 2278
Query: 2281 CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCP 2340
CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQL EWRRPDFCP QCP
Sbjct: 2279 CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCP 2338
Query: 2341 AHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRY 2400
AHSHYELCGDSCP SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHD RY
Sbjct: 2339 AHSHYELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRY 2398
Query: 2401 YPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANG 2460
YPLG+ FYPGP C+ C C GG V+C E ++CGPHE CR G C A G C A+G
Sbjct: 2399 YPLGQTFYPGPGCDSLCRCREGGEVSC-EPSSCGPHETCRPSGGSLGCVAVGSTTCQASG 2457
Query: 2461 GIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGD-----LQRLLVTVA 2515
HY T DGR +D G+C YVLAQ C +PG F+++ E A G+ + + V VA
Sbjct: 2458 DPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVA 2517
Query: 2516 GQVVSLAQGQ-QVTVDGEAVALPV--AVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLM 2572
+ L Q Q +VTV+G + LPV A G++R + G ++V++T GLR+ +D ++ +
Sbjct: 2518 NFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRV 2577
Query: 2573 SIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGC-------- 2624
++P + +CGLCGN+NG+ DDF PNGS A + FG +W C
Sbjct: 2578 TVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPP 2637
Query: 2625 -GEGCGP-QGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCA 2682
EGC P + CP L ++ Y+ E CG L +P GP ++C ++ P + C++DLC
Sbjct: 2638 GSEGCIPSEECPPELEKK---YQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCL 2694
Query: 2683 QKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALS 2742
G+ + LC ++ AY +ACQAAG V+PWR ++FCP+ CP +SHY +C TC C+ALS
Sbjct: 2695 GGGNLSILCSNIHAYVSACQAAGGQVEPWRNETFCPMECPQNSHYELCADTCSLGCSALS 2754
Query: 2743 GLTGCTTRCFEGCECDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSS 2802
C C EGC+CD FL + C+P+Q CGC HNG Y ++L +C ++C+C
Sbjct: 2755 APLQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGAYYEPEQTVLIDNCRQQCTCHV 2814
Query: 2803 SSGLTCQAAGCPPGRVCEVKAEARNC-------------------WATRGLCVLSVGA-- 2841
+ CQ C PG+VC+ +C +G+C+ + A
Sbjct: 2815 GKVVVCQEHSCKPGQVCQPSGGILSCVNKDPCHGVTCRPQETCKEQGGQGVCLPNYEATC 2874
Query: 2842 ------NLTTFDGARGATTSPGVYELSSR-CPGL--QNTIPWYRVVAEVQICHGKTEAVG 2892
+ +FDG + Y L++ CPG+ Q P + V + Q + AV
Sbjct: 2875 WLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTP-FTVTTKNQ--NRGNPAVS 2931
Query: 2893 QVHIFFQDGMVT-LTPNKG----VWVNGLRVDLPAEKL-ASVSVSRTPDGSLLVRQKAGV 2946
V + + T ++ +K V VNG+ LP +SV++ +LLV G+
Sbjct: 2932 YVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVAD-FGL 2990
Query: 2947 QVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTND--WHDSQEKPAME----KWRAQDF 3000
QV N +V V + + + G +CG CGN D + ND + + P++ WRA +
Sbjct: 2991 QVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGW 3050
Query: 3001 SP 3002
P
Sbjct: 3051 DP 3052
Score = 4486 bits (11635), Expect = 0.0
Identities = 2101/2570 (81%), Positives = 2214/2570 (86%), Gaps = 24/2570 (0%)
Query: 444 CEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVEL-C 502
C G+ C + C+ GG+ C+ A C GDPHY +FDGR++D GTC+Y + C
Sbjct: 2846 CHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGC 2905
Query: 503 SEDDT--LPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLP 560
T L F+V KN++RG+ VSYV +VTV A ++S+ + E+G V V+ + LP
Sbjct: 2906 PGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALP 2965
Query: 561 VSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPAD 620
VS+++GR+ V Q +A++ FGL V+YDW+ ++ ++LP+ + VCGLCGN + +P +
Sbjct: 2966 VSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNN 3025
Query: 621 DFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTK- 679
D + P+G LAP + SW+ D LC D C+ +CP C + + YEG CG L
Sbjct: 3026 DQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPG 3085
Query: 680 LDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPA 739
GPF CH + P F + CV D+C+ GG+R LC+ L++Y AC G+ + DWR+
Sbjct: 3086 TGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV 3145
Query: 740 NCPLSCPANSRYELCGPACPTSCNGAA---APSNCSGRPCVEGCVCLPGFVASGGACVPA 796
C ++CP NS YE+CGP CP SC A P+ C G PCVEGC C GFV S CVP
Sbjct: 3146 GCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEG-PCVEGCQCDAGFVLSADRCVPL 3204
Query: 797 SS-CGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSV-QNGLL 854
++ CGC G G E WAD C + C C + C SC GE C + +G
Sbjct: 3205 NNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPA-SCGLGEVCGLLPSGQH 3263
Query: 855 GCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSC-GQNAALPAFRVLVENEHRG 913
GC P CQ GDPHYV+ DG RFDF GTC YLL C G F V V NEHRG
Sbjct: 3264 GCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG 3323
Query: 914 SQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRT 973
SQ VSYTR+V ++ + + +P ++ VD V LPFQ D + G D VV T
Sbjct: 3324 SQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQL-DSLLHAHLSGADVVVTT 3382
Query: 974 DFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQ 1033
GL++ +D ++ V +VP++YA +LCGLCGN+N DPADDL GG A WQ
Sbjct: 3383 TSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPAG--------WQ 3434
Query: 1034 EETRPGCGATEPGDCPKLDSLVAQQ-LQSKNECGILADPKGPFRECHSKLDPQGAVRDCV 1092
GCG CP + Q+ + CG+++ GP CH + P + C+
Sbjct: 3435 VGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCL 3494
Query: 1093 YDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLS 1152
D C + G G LC A+ATY AACQAAGA + WR + CP CP HSHYE C CP S
Sbjct: 3495 LDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGS 3554
Query: 1153 CGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDS 1212
C L P GC S C EGCVCD GF LSG++C+P+ CGC+H Y+P GQTFYPGPGCDS
Sbjct: 3555 CPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDS 3614
Query: 1213 LCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMG 1272
LC C+EGG VSCE SSCGPHE C+PSGGSLGCVAVGS+TCQASGDPHYTTFDG RFDFMG
Sbjct: 3615 LCRCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGHRFDFMG 3674
Query: 1273 TCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVN 1332
TCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVN
Sbjct: 3675 TCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVN 3734
Query: 1333 GVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGN 1392
GVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQ MCGLCGN
Sbjct: 3735 GVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGN 3794
Query: 1393 YNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELE 1452
YNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPP CPPGS CIPS KCPPELE
Sbjct: 3795 YNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSAGCIPSDKCPPELE 3854
Query: 1453 KKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSAC 1512
KKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSAC
Sbjct: 3855 KKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSAC 3914
Query: 1513 QAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGF 1572
QAAGGHVEPWR ETFCPMECP NSHYELCADTCSLGCSALSAP QC DGCAEGCQCDSGF
Sbjct: 3915 QAAGGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQCDSGF 3974
Query: 1573 LYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEHSCKPGQVCQP 1632
LYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCH GK +VCQEHSCKPGQVCQP
Sbjct: 3975 LYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQVCQP 4034
Query: 1633 SGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQ 1692
SGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQ
Sbjct: 4035 SGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQ 4094
Query: 1693 GTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIG 1752
GTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIG
Sbjct: 4095 GTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIG 4154
Query: 1753 KVRVCVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGA 1812
KVRV NGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGA
Sbjct: 4155 KVRV--NGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGA 4212
Query: 1813 VCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLE 1872
VCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLE
Sbjct: 4213 VCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLE 4272
Query: 1873 QYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAAC 1932
QYEGPGFCGPL+SGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAAC
Sbjct: 4273 QYEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAAC 4332
Query: 1933 QAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCD 1992
QAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCD
Sbjct: 4333 QAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCD 4392
Query: 1993 AGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGL 2052
AGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGL
Sbjct: 4393 AGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGL 4452
Query: 2053 GEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAE 2112
GEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAE
Sbjct: 4453 GEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAE 4512
Query: 2113 NFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHA 2172
NFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHA
Sbjct: 4513 NFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHA 4572
Query: 2173 HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA 2232
HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA
Sbjct: 4573 HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA 4632
Query: 2233 GWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQ 2292
GWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQ
Sbjct: 4633 GWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQ 4692
Query: 2293 GCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSC 2352
GCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSC
Sbjct: 4693 GCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSC 4752
Query: 2353 PVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPE 2412
PVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPE
Sbjct: 4753 PVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPE 4812
Query: 2413 CERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVY 2472
CERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVY
Sbjct: 4813 CERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVY 4872
Query: 2473 DLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVSLAQGQQVTVDGE 2532
DLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVSLAQGQQVTVDGE
Sbjct: 4873 DLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVSLAQGQQVTVDGE 4932
Query: 2533 AVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGN 2592
AVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGN
Sbjct: 4933 AVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGN 4992
Query: 2593 WSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQ 2652
WSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQ
Sbjct: 4993 WSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQ 5052
Query: 2653 LRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWR 2712
LRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWR
Sbjct: 5053 LRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWR 5112
Query: 2713 TDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQ 2772
TDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQ
Sbjct: 5113 TDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQ 5172
Query: 2773 DCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATR 2832
DCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATR
Sbjct: 5173 DCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATR 5232
Query: 2833 GLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVG 2892
GLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVG
Sbjct: 5233 GLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVG 5292
Query: 2893 QVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQVWLGA 2952
QVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQVWLGA
Sbjct: 5293 QVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQVWLGA 5352
Query: 2953 NGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHDSQEKPAMEKWRAQDFSP 3002
NGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHDSQEKPAMEKWRAQDFSP
Sbjct: 5353 NGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHDSQEKPAMEKWRAQDFSP 5402
Score = 3559 bits (9229), Expect = 0.0
Identities = 1713/2627 (65%), Positives = 1938/2627 (73%), Gaps = 86/2627 (3%)
Query: 444 CEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVEL-C 502
C G+ C + C+ GG+ C+ A C GDPHY +FDGR++D GTC+Y + C
Sbjct: 1645 CHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGC 1704
Query: 503 SEDDT--LPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLP 560
T L F+V KN++RG+ VSYV +VTV A ++S+ + E+G V V+ + LP
Sbjct: 1705 PGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALP 1764
Query: 561 VSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPAD 620
VS+++GR+ V Q +A++ FGL V+YDW+ ++ ++LP+ + VCGLCGN + +P +
Sbjct: 1765 VSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNN 1824
Query: 621 DFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTK- 679
D + P+G LAP + SW+ D LC D C+ +CP C + + YEG CG L
Sbjct: 1825 DQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPG 1884
Query: 680 LDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPA 739
GPF CH + P F + CV D+C+ GG+R LC+ L++Y AC G+ + DWR+
Sbjct: 1885 TGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV 1944
Query: 740 NCPLSCPANSRYELCGPACPTSCNGAA---APSNCSGRPCVEGCVCLPGFVASGGACVPA 796
C ++CP NS YE+CG CP SC A P+ C G PCVEGC C GFV S CVP
Sbjct: 1945 GCEITCPENSHYEVCGSPCPASCPSPAPLTTPAVCEG-PCVEGCQCDAGFVLSADRCVPL 2003
Query: 797 SS-CGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSV-QNGLL 854
++ CGC G G E WAD C + C C + C SC GE C + +G
Sbjct: 2004 NNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPA-SCGLGEVCGLLPSGQH 2062
Query: 855 GCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSC-GQNAALPAFRVLVENEHRG 913
GC P CQ GDPHYV+ DG RF+F GTC YLL C G F V V NEHRG
Sbjct: 2063 GCQPVSTAECQAWGDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG 2122
Query: 914 SQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRT 973
SQ VSYTR+V ++ + + +P ++ VD V LPFQ D + G D VV T
Sbjct: 2123 SQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQL-DSLLHAHLSGADVVVTT 2181
Query: 974 DFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQ 1033
GL++ +D ++ V +VP++YA +LCGLCGN+N DPADDL GG A WQ
Sbjct: 2182 TSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPAG--------WQ 2233
Query: 1034 EETRPGCGATEPGDCPKLDSLVAQQ-LQSKNECGILADPKGPFRECHSKLDPQGAVRDCV 1092
GCG CP + Q+ + CG+++ GP CH + P + C+
Sbjct: 2234 VGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCL 2293
Query: 1093 YDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLS 1152
D C + G G LC A+ATY AACQAAGA + WR + CP CP HSHYE C CP S
Sbjct: 2294 LDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGS 2353
Query: 1153 CGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDS 1212
C L P GC S C EGCVCD GF LSG++C+P+ CGC+H Y+P GQTFYPGPGCDS
Sbjct: 2354 CPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDS 2413
Query: 1213 LCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMG 1272
LC C+EGG VSCE SSCGPHE C+PSGGSLGCVAVGS+TCQASGDPHYTTFDGRRFDFMG
Sbjct: 2414 LCRCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGRRFDFMG 2473
Query: 1273 TCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVN 1332
TCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVN
Sbjct: 2474 TCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVN 2533
Query: 1333 GVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGN 1392
GVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQ MCGLCGN
Sbjct: 2534 GVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGN 2593
Query: 1393 YNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELE 1452
YNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPP CPPGSE CIPS +CPPELE
Sbjct: 2594 YNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSEGCIPSEECPPELE 2653
Query: 1453 KKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSAC 1512
KKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSAC
Sbjct: 2654 KKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSAC 2713
Query: 1513 QAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGF 1572
QAAGG VEPWR ETFCPMECP NSHYELCADTCSLGCSALSAP QC DGCAEGCQCDSGF
Sbjct: 2714 QAAGGQVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQCDSGF 2773
Query: 1573 LYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEHSCKPGQVCQP 1632
LYNGQACVPIQQCGCYHNG YYEPEQTVLIDNCRQQCTCH GK +VCQEHSCKPGQVCQP
Sbjct: 2774 LYNGQACVPIQQCGCYHNGAYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQVCQP 2833
Query: 1633 SGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQ 1692
SGGILSCV KDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQ
Sbjct: 2834 SGGILSCVNKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQ 2893
Query: 1693 GTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIG 1752
GTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIG
Sbjct: 2894 GTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIG 2953
Query: 1753 KVRVCVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGA 1812
KVR VNGVLTALPVSVADGRISV QGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGA
Sbjct: 2954 KVR--VNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGA 3011
Query: 1813 VCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLE 1872
VCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLE
Sbjct: 3012 VCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLE 3071
Query: 1873 QYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAAC 1932
QYEGPGFCGPLA GTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAAC
Sbjct: 3072 QYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAAC 3131
Query: 1933 QAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCD 1992
QAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCD
Sbjct: 3132 QAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCD 3191
Query: 1993 AGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGL 2052
AGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGL
Sbjct: 3192 AGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGL 3251
Query: 2053 GEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAE 2112
GEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAE
Sbjct: 3252 GEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAE 3311
Query: 2113 NFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHA 2172
NFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFV LPFQLDSLLHA
Sbjct: 3312 NFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHA 3371
Query: 2173 HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA 2232
HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYA SLCGLCGNYNQDPADDLKAVGGKPA
Sbjct: 3372 HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPA 3431
Query: 2233 GWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQ 2292
GWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQ
Sbjct: 3432 GWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQ 3491
Query: 2293 GCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSC 2352
GCLLDACQVQGHPGGLCPAVATYVAACQAAGAQL EWRRPDFCP QCPAHSHYELCGDSC
Sbjct: 3492 GCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSC 3551
Query: 2353 PVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPE 2412
P SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHD RYYPLG+ FYPGP
Sbjct: 3552 PGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPG 3611
Query: 2413 CERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVY 2472
C+ C C GG V+C E ++CGPHE CR G C A G C A+G HY T DG +
Sbjct: 3612 CDSLCRCREGGEVSC-EPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGHRF 3670
Query: 2473 DLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGD-----LQRLLVTVAGQVVSLAQGQ-Q 2526
D G+C YVLAQ C +PG F+++ E A G+ + + V VA + L Q Q +
Sbjct: 3671 DFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWK 3730
Query: 2527 VTVDGEAVALPV--AVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCG 2584
VTV+G + LPV A G++R + G ++V++T GLR+ +D ++ +++P + +CG
Sbjct: 3731 VTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCG 3790
Query: 2585 LCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGC-GEGCGPQGCPVCLAEETAP 2643
LCGN+NG+ DDF PNGS A + FG +W C P G C+ + P
Sbjct: 3791 LCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSAGCIPSDKCP 3850
Query: 2644 ------YESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAY 2697
Y+ E CG L +P GP ++C ++ P + C++DLC G+ + LC ++ AY
Sbjct: 3851 PELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAY 3910
Query: 2698 TAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCEC 2757
+ACQAAG V+PWR ++FCP+ CP +SHY +C TC C+ALS C C EGC+C
Sbjct: 3911 VSACQAAGGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQC 3970
Query: 2758 DDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGR 2817
D FL + C+P+Q CGC HNG Y ++L +C ++C+C + CQ C PG+
Sbjct: 3971 DSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQ 4030
Query: 2818 VCEVKAEARNC-------------------WATRGLCVLSVGA--------NLTTFDGAR 2850
VC+ +C +G+C+ + A + +FDG +
Sbjct: 4031 VCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRK 4090
Query: 2851 GATTSPGVYELSSR-CPGL--QNTIPWYRVVAEVQICHGKTEAVGQVHIFFQDGMVT-LT 2906
Y L++ CPG+ Q P + V + Q + AV V + + T ++
Sbjct: 4091 FDFQGTCNYVLATTGCPGVSTQGLTP-FTVTTKNQ--NRGNPAVSYVRVVTVAALGTNIS 4147
Query: 2907 PNKG----VWVNGLRVDLPAEKL-ASVSVSRTPDGSLLVRQKAGVQVWLGANGKVAVIVS 2961
+K V VNG+ LP +SV++ +LLV G+QV N +V V +
Sbjct: 4148 IHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVAD-FGLQVSYDWNWRVDVTLP 4206
Query: 2962 NDHAGKLCGACGNFDGDQTND--WHDSQEKPAME----KWRAQDFSP 3002
+ + G +CG CGN D + ND + + P++ WRA + P
Sbjct: 4207 SSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDP 4253
Score = 1172 bits (3033), Expect = 0.0
Identities = 687/1850 (37%), Positives = 950/1850 (51%), Gaps = 139/1850 (7%)
Query: 441 EPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVE 500
E SCE C + C+ GG GCVA + C+A GDPHYTTFDG R+D MGTC Y + +
Sbjct: 3623 EVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGHRFDFMGTCVYVLAQ 3682
Query: 501 LCSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLP 560
C L F+V +N G+ RVS ++TV+ + ++ L + + V V+ +LP
Sbjct: 3683 TCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQ-WKVTVNGVDMKLP 3741
Query: 561 VSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPAD 620
V L+ G++R Q G V+E FGL V YD + +++P + +CGLCGNYNGDP D
Sbjct: 3742 VVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGNYNGDPKD 3801
Query: 621 DFLTPDGALAPDAVEFASSWK--LDDGDYL----CEDGCQNNCPA--CTPGQAQHYEGDR 672
DF P+G+ A +A EF +SW+ + D L C G P+ C P + Y+ +
Sbjct: 3802 DFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSAGCIPSDKCPPELEKKYQKEE 3861
Query: 673 LCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISV 732
CG+L+ GP + CH +DP+ L+ C++DLC+ GG LC + AY AC G V
Sbjct: 3862 FCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHV 3921
Query: 733 GDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGA 792
WR+ CP+ CP NS YELC C C+ +AP C C EGC C GF+ +G A
Sbjct: 3922 EPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPD-GCAEGCQCDSGFLYNGQA 3980
Query: 793 CVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCN----GATHQVTCRDKQSC-PAG--- 844
CVP CGC G+ P Q V D C+++CTC+ + +C+ Q C P+G
Sbjct: 3981 CVPIQQCGCYHNGVYYEPEQTVLIDN-CRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGIL 4039
Query: 845 ----------------ERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTY 888
E C Q G C P+ TC GDPHY SFDGR+FDF GTC Y
Sbjct: 4040 SCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNY 4099
Query: 889 LL--VGSCG-QNAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVD 945
+L G G L F V +N++RG+ VSY R V V A G +++ ++ G+V V+
Sbjct: 4100 VLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVN 4159
Query: 946 DVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGN 1005
VL LP ADG++ V + A++ DFGL V+YDWN RV +PSSY A+CGLCGN
Sbjct: 4160 GVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGN 4219
Query: 1006 FNGDPADDLALRGGGQAANALAFGNSWQEE-TRPGCGATEPGDCPKLDSLVAQQLQSKNE 1064
+ +P +D G A + +G SW+ P C G CP +Q +
Sbjct: 4220 MDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGF 4279
Query: 1065 CGILAD-PKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATV 1123
CG L+ GPF CH+ + P+ + CV D C+ G LC ALA+Y AACQAAG +
Sbjct: 4280 CGPLSSGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVI 4339
Query: 1124 HPWRSEELCPLSCPPHSHYEACSYGCPLSC---GDLPVPGGCGSECHEGCVCDEGFALSG 1180
WR++ C ++CP +SHYE C CP SC L P C C EGC CD GF LS
Sbjct: 4340 EDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSA 4399
Query: 1181 ESCLPLAS-CGCVHQGTYHPPGQTFYPGPGCDSLCHC-QEGGLVSCESSSCGPHEAC--Q 1236
+ C+PL + CGC GTYH G F+ C C C GG + C +SCG E C
Sbjct: 4400 DRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLL 4459
Query: 1237 PSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRP-GLHRFAVLQ 1295
PS G GC V ++ CQA GDPHY T DG RFDF GTC Y+L+ C P G F V
Sbjct: 4460 PS-GQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTV 4518
Query: 1296 ENVAWGNGRVSVTRVITVQVANFTLRLEQRQW--KVTVNGVDMKLPVVLANGQIRASQHG 1353
N G+ VS TR +T+Q+ N +L L R W K+ V+GV + LP L + + A G
Sbjct: 4519 ANEHRGSQAVSYTRSVTLQIYNHSLTLSAR-WPRKLQVDGVFVALPFQL-DSLLHAHLSG 4576
Query: 1354 SDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQ----KPNGSQA 1409
+DVV+ T GL +A+D +VR+ VP Y +CGLCGNYN DP DD + KP G Q
Sbjct: 4577 ADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAGWQV 4636
Query: 1410 GNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTG 1469
G A G C+ PCP C PE ++ + + CG++S+ G
Sbjct: 4637 GGAQGCGE----------CV-SKPCP---------SPCTPEQQESFGGPDACGVISATDG 4676
Query: 1470 PLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCP 1529
PL+ CH LV P + C+ D C G+ LC + YV+ACQAAG + WR FCP
Sbjct: 4677 PLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCP 4736
Query: 1530 MECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYH 1589
++CP +SHYELC D+C + C +LSAP C+ C EGC CD+GF+ +G CVP+ QCGC H
Sbjct: 4737 LQCPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLH 4796
Query: 1590 NGVYYEPEQTVLI--DNCRQQCTCHAGKGMVCQE-HSCKPGQVCQPSGGILSCVTKDPCH 1646
+G YY P V C ++C C G + CQE +C P + C+ G+ CH
Sbjct: 4797 DGRYY-PLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGV------QACH 4849
Query: 1647 GVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPG 1706
C G CL N G HY + DGR +D G+C+YVLA P
Sbjct: 4850 ATGC------------GRCLAN--------GGIHYITLDGRVYDLHGSCSYVLAQVCHP- 4888
Query: 1707 VSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGVLTALP 1766
G F++ + G+ ++ + V G +S+ + + +V V+G ALP
Sbjct: 4889 --KPGDEDFSIVLEKNAAGD-----LQRLLVTVAGQVVSLAQGQ----QVTVDGEAVALP 4937
Query: 1767 VSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNN 1826
V+V GR+ V +L GL++ +D + + +++PS + G +CGLCGN + N ++
Sbjct: 4938 VAV--GRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSD 4995
Query: 1827 DQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDEC-RGSCPTCPEDRLEQYEGPGFCGPLAS 1885
D V PNG+ A S+ +G +WRAPG C + C CP C + YE CG L +
Sbjct: 4996 DFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRN 5055
Query: 1886 GTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQ 1945
GPF TC A + P +F+ CV D+C GD+ LC++LA+Y AACQAAGV ++ WR
Sbjct: 5056 -PQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTD 5114
Query: 1946 VGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPL 2005
C + CP +SHY +C C SC + + LT C C EGC+CD F+LS C+P+
Sbjct: 5115 SFCPLHCPAHSHYSICTRTCQGSCAALSGLTG---CTTRCFEGCECDDRFLLSQGVCIPV 5171
Query: 2006 NNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHG 2065
+ CGC NG Y S CS+ C C G L C A C G VC + ++
Sbjct: 5172 QD-CGCTHNGRYLPVNSSL-LTSDCSERCSCSSSSG-LTCQAAGCPPGRVCEVKAEARN- 5227
Query: 2066 CQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANE--HR 2123
C + C + T DG R Y LS+ C G + V + H
Sbjct: 5228 CW-ATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHG 5286
Query: 2124 GSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQ-LDSLLHAHLSGADVVVT 2182
++AV V + + +TL+ + + V+G+ V LP + L S+ + ++V
Sbjct: 5287 KTEAVG---QVHIFFQDGMVTLTPN--KGVWVNGLRVDLPAEKLASVSVSRTPDGSLLVR 5341
Query: 2183 TTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA 2232
+G+ + + V + V +A LCG CGN++ D +D KPA
Sbjct: 5342 QKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHDSQEKPA 5391
>gi|239757282 PREDICTED: similar to Fc fragment of IgG binding protein
[Homo sapiens]
Length = 1403
Score = 2930 bits (7596), Expect = 0.0
Identities = 1357/1373 (98%), Positives = 1361/1373 (99%), Gaps = 2/1373 (0%)
Query: 1631 QPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFD 1690
QP +L ++ DPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFD
Sbjct: 33 QPLKVLLPLLSPDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFD 92
Query: 1691 FQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDE 1750
FQGTCNYVLATTGC GVSTQGLTPFTVTTKN+NRGNPAVSYVRVVTVAALGTNISIHKDE
Sbjct: 93 FQGTCNYVLATTGCLGVSTQGLTPFTVTTKNENRGNPAVSYVRVVTVAALGTNISIHKDE 152
Query: 1751 IGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYH 1810
IGKVRV NGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYH
Sbjct: 153 IGKVRV--NGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYH 210
Query: 1811 GAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDR 1870
GAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDR
Sbjct: 211 GAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDR 270
Query: 1871 LEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVA 1930
LEQYEGPGFCGPLA GTGGPFTTCHAHVPPESFFKGCVLDVCMGGGD DILCKALASYVA
Sbjct: 271 LEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVA 330
Query: 1931 ACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQ 1990
ACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQ
Sbjct: 331 ACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQ 390
Query: 1991 CDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASC 2050
CDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASC
Sbjct: 391 CDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASC 450
Query: 2051 GLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLG 2110
GLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLG
Sbjct: 451 GLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLG 510
Query: 2111 AENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLL 2170
AENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLL
Sbjct: 511 AENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLL 570
Query: 2171 HAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGK 2230
HAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGK
Sbjct: 571 HAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGK 630
Query: 2231 PAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQY 2290
PAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQY
Sbjct: 631 PAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQY 690
Query: 2291 FQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGD 2350
FQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGD
Sbjct: 691 FQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGD 750
Query: 2351 SCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPG 2410
SCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPG
Sbjct: 751 SCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPG 810
Query: 2411 PECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGR 2470
PECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGR
Sbjct: 811 PECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGR 870
Query: 2471 VYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVSLAQGQQVTVD 2530
VYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVSLAQGQQVTVD
Sbjct: 871 VYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVSLAQGQQVTVD 930
Query: 2531 GEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFN 2590
GEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFN
Sbjct: 931 GEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFN 990
Query: 2591 GNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEAC 2650
GNWSDDFVLPNGSAASSVETFGAAWR PGSSKGCGEGCGPQGCPVCLAEETAPYESNEAC
Sbjct: 991 GNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEGCGPQGCPVCLAEETAPYESNEAC 1050
Query: 2651 GQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKP 2710
GQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKP
Sbjct: 1051 GQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKP 1110
Query: 2711 WRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIP 2770
WRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIP
Sbjct: 1111 WRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIP 1170
Query: 2771 VQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWA 2830
VQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWA
Sbjct: 1171 VQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWA 1230
Query: 2831 TRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEA 2890
TRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEA
Sbjct: 1231 TRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEA 1290
Query: 2891 VGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQVWL 2950
VGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQVWL
Sbjct: 1291 VGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQVWL 1350
Query: 2951 GANGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHDSQEKPAMEKWRAQDFSPW 3003
GANGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHDSQEKPAMEKWRAQDFSPW
Sbjct: 1351 GANGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHDSQEKPAMEKWRAQDFSPW 1403
Score = 1024 bits (2648), Expect = 0.0
Identities = 554/1435 (38%), Positives = 776/1435 (54%), Gaps = 90/1435 (6%)
Query: 436 VLSPVEPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCS 495
+LSP C G+ C + C+ GG+ C+ A C GDPHY +FDGR++D GTC+
Sbjct: 41 LLSP--DPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCN 98
Query: 496 YTMVE---LCSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLV 552
Y + L L F+V KNE+RG+ VSYV +VTV A ++S+ + E+G V V
Sbjct: 99 YVLATTGCLGVSTQGLTPFTVTTKNENRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRV 158
Query: 553 DNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCG 612
+ + LPVS+++GR+ V Q +A++ FGL V+YDW+ ++ ++LP+ + VCGLCG
Sbjct: 159 NGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCG 218
Query: 613 NYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDR 672
N + +P +D + P+G LAP + SW+ D LC D C+ +CP C + + YEG
Sbjct: 219 NMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPG 278
Query: 673 LCGMLTK-LDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGIS 731
CG L GPF CH + P F + CV D+C+ GG+ LC+ L++Y AC G+
Sbjct: 279 FCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVV 338
Query: 732 VGDWRSPANCPLSCPANSRYELCGPACPTSCNGAA---APSNCSGRPCVEGCVCLPGFVA 788
+ DWR+ C ++CP NS YE+CGP CP SC A P+ C G PCVEGC C GFV
Sbjct: 339 IEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEG-PCVEGCQCDAGFVL 397
Query: 789 SGGACVPASS-CGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERC 847
S CVP ++ CGC G G E WAD C + C C + C SC GE C
Sbjct: 398 SADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPA-SCGLGEVC 456
Query: 848 SV-QNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSC-GQNAALPAFRV 905
+ +G GC P CQ GDPHYV+ DG RFDF GTC YLL C G F V
Sbjct: 457 GLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTV 516
Query: 906 LVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQ 965
V NEHRGSQ VSYTR+V ++ + + +P ++ VD V LPFQ D +
Sbjct: 517 TVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQL-DSLLHAHLS 575
Query: 966 GRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANA 1025
G D VV T GL++ +D ++ V +VP++YA +LCGLCGN+N DPADDL GG A
Sbjct: 576 GADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAG-- 633
Query: 1026 LAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQ-LQSKNECGILADPKGPFRECHSKLDP 1084
WQ GCG CP + Q+ + CG+++ GP CH + P
Sbjct: 634 ------WQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPP 687
Query: 1085 QGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEA 1144
+ C+ D C + G G LC A+ATY AACQAAGA + WR + CPL CP HSHYE
Sbjct: 688 AQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYEL 747
Query: 1145 CSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTF 1204
C CP+SC L P GC S C EGCVCD GF LSG++C+P+ CGC+H G Y+P G+ F
Sbjct: 748 CGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVF 807
Query: 1205 YPGPGCDSLCHCQEGGLVSC-ESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTF 1263
YPGP C+ C C GG V+C E ++CGPHE C+ G C A G C A+G HY T
Sbjct: 808 YPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITL 867
Query: 1264 DGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLE 1323
DGR +D G+C YVLAQ C +PG F+++ E A G+ + + V VA + L
Sbjct: 868 DGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGD-----LQRLLVTVAGQVVSLA 922
Query: 1324 QRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYY 1383
Q Q +VTV+G + LPV A G++R + G ++V++T GLR+ +D ++ +++P +
Sbjct: 923 QGQ-QVTVDGEAVALPV--AVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFR 979
Query: 1384 QQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPC-PPGSEDCI 1442
++CGLCGN+NG+ DDF PNGS A + FG +W VP S C P G C+
Sbjct: 980 GRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWR--VPGSSKGCGEGCGPQGCPVCL 1037
Query: 1443 PSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILC 1502
P Y+ E CG L +P GP ++C ++ P + C++DLC G+ + LC
Sbjct: 1038 AEETAP------YESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLC 1091
Query: 1503 SNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGC 1562
++ AY +ACQAAG V+PWRT++FCP+ CP +SHY +C TC C+ALS C C
Sbjct: 1092 RSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRC 1151
Query: 1563 AEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEH 1622
EGC+CD FL + C+P+Q CGC HNG Y ++L +C ++C+C + G+ CQ
Sbjct: 1152 FEGCECDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAA 1211
Query: 1623 SCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYH 1682
C PG+VC+ +C +G+C+ + A +
Sbjct: 1212 GCPPGRVCEVKAEARNC-------------------WATRGLCVLSVGA--------NLT 1244
Query: 1683 SFDGRKFDFQGTCNYVLATTGCPGVSTQGLTP-FTVTTKNQ--NRGNPAVSYVRVVTVAA 1739
+FDG + Y L++ CPG+ Q P + V + Q + AV V +
Sbjct: 1245 TFDGARGATTSPGVYELSSR-CPGL--QNTIPWYRVVAEVQICHGKTEAVGQVHIFFQDG 1301
Query: 1740 LGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVAD-FGLQVSYDWN 1798
+ T ++ +K V VNG+ LP +SV++ +LLV G+QV N
Sbjct: 1302 MVT-LTPNKG------VWVNGLRVDLPAEKL-ASVSVSRTPDGSLLVRQKAGVQVWLGAN 1353
Query: 1799 WRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDP 1853
+V V + + + G +CG CGN D + ND + + P++ WRA + P
Sbjct: 1354 GKVAVIVSNDHAGKLCGACGNFDGDQTND--WHDSQEKPAME----KWRAQDFSP 1402
Score = 892 bits (2306), Expect = 0.0
Identities = 520/1420 (36%), Positives = 726/1420 (51%), Gaps = 129/1420 (9%)
Query: 1224 CESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQT-C 1282
C +C P E C+ GG C+ +TC GDPHY +FDGR+FDF GTC YVLA T C
Sbjct: 47 CHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGC 106
Query: 1283 --GTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQ-WKVTVNGVDMKLP 1339
+ GL F V +N GN VS RV+TV + + + + KV VNGV LP
Sbjct: 107 LGVSTQGLTPFTVTTKNENRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALP 166
Query: 1340 VVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKD 1399
V +A+G+I +Q S ++ DFGL+V+YD + V VT+P +Y+ +CGLCGN + +P +
Sbjct: 167 VSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNN 226
Query: 1400 DFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPT--PCPPGSEDCIPSHKCPPELEKKYQK 1457
D PNG+ A + +G SW D C CP CP + ++Y+
Sbjct: 227 DQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPT----------CPEDRLEQYEG 276
Query: 1458 EEFCGLLSSPTG-PLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAG 1516
FCG L+ TG P ++CH V P+ K C+ D+C+GGG+ ILC + +YV+ACQAAG
Sbjct: 277 PGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAG 336
Query: 1517 GHVEPWRTETFCPMECPPNSHYELCADTCSLGCSA---LSAPPQCQDGCAEGCQCDSGFL 1573
+E WR + C + CP NSHYE+C C C + L+ P C+ C EGCQCD+GF+
Sbjct: 337 VVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFV 396
Query: 1574 YNGQACVPIQQ-CGCYHNGVYYEPEQTVLIDN-CRQQCTCHAGKGMVCQEHSCKPGQVCQ 1631
+ CVP+ CGC+ NG Y+E D C Q C C
Sbjct: 397 LSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCG------------------- 437
Query: 1632 PSGGILSCVTKDPCHGVTCRPQETC-KEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFD 1690
P GG L C +C E C GQ C P A C WGDPHY + DG +FD
Sbjct: 438 PGGGSLVCTP------ASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFD 491
Query: 1691 FQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDE 1750
FQGTC Y+L+ C G G FTVT N++RG+ AVSY R VT+ ++++
Sbjct: 492 FQGTCEYLLSAP-CHG-PPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARW 549
Query: 1751 IGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYH 1810
K++ V+GV ALP + D + + ++ GL +++D + V + +P++Y
Sbjct: 550 PRKLQ--VDGVFVALPFQL-DSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYA 606
Query: 1811 GAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPT-CPED 1869
++CGLCGN +++P +D G A W+ G C + CP+ C +
Sbjct: 607 ASLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQG-CGECVSKPCPSPCTPE 657
Query: 1870 RLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYV 1929
+ E + GP CG + S T GP CH VPP +F+GC+LD C G LC A+A+YV
Sbjct: 658 QQESFGGPDACG-VISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYV 716
Query: 1930 AACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGC 1989
AACQAAG + +WR C + CP +SHYE+CG CP SCPS L+ P CE C EGC
Sbjct: 717 AACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPS---LSAPEGCESACREGC 773
Query: 1990 QCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPAS 2049
CDAGFVLS D CVP+ CGC +G Y+ G F+ C + C CGPGG A+
Sbjct: 774 VCDAGFVLSGDTCVPVGQ-CGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAA 832
Query: 2050 CGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPL 2109
CG E C L G C C A G HY+TLDG +D G+C Y+L+ CH P
Sbjct: 833 CGPHEEC-RLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKP- 890
Query: 2110 GAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSL 2169
G E+F++ + G L + +S +++ VDG VALP +
Sbjct: 891 GDEDFSIVLEKNAAGDLQ-------RLLVTVAGQVVSLAQGQQVTVDGEAVALPVAV-GR 942
Query: 2170 LHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGG 2229
+ G ++V+ TT GL L FDGD+ + + +P+ + LCGLCGN+N + +DD G
Sbjct: 943 VRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNG 1002
Query: 2230 KP--------AGWQV-GGAQGCGE-CVSKPCPSPCTPEQQESFGGPDACGVISATDGPLA 2279
A W+V G ++GCGE C + CP C E+ + +ACG + GP A
Sbjct: 1003 SAASSVETFGAAWRVPGSSKGCGEGCGPQGCP-VCLAEETAPYESNEACGQLRNPQGPFA 1061
Query: 2280 PCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQC 2339
C ++ P++YF+ C+ D C +G LC ++A Y AACQAAG + WR FCPL C
Sbjct: 1062 TCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHC 1121
Query: 2340 PAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGR 2399
PAHSHY +C +C SC +LS GC + C EGC CD F+LS C+PV CGC H+GR
Sbjct: 1122 PAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQDCGCTHNGR 1181
Query: 2400 YYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLAN 2459
Y P+ +C RC C +TCQ A C P C ++ + C AT G C+ +
Sbjct: 1182 YLPVNSSLLTS-DCSERCSCSSSSGLTCQ-AAGCPPGRVCEVKAEARNCWATR-GLCVLS 1238
Query: 2460 GGIHYITLDGR--------VYDLHGSCS-----------YVLAQVCHPKPGDEDFSIVLE 2500
G + T DG VY+L C Q+CH K
Sbjct: 1239 VGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGK----------- 1287
Query: 2501 KNAAGDLQRLLVTVAGQVVSLAQGQQVTVDGEAVALP---VAVGRVRVTAEGRNMVLQTT 2557
A G + + +V+L + V V+G V LP +A V T +G +V Q
Sbjct: 1288 TEAVGQVH---IFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKA 1344
Query: 2558 KGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDF 2597
G+++ + + + + + G+LCG CGNF+G+ ++D+
Sbjct: 1345 -GVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTNDW 1383
>gi|239757286 PREDICTED: similar to Fc fragment of IgG binding protein
[Homo sapiens]
Length = 1472
Score = 2726 bits (7067), Expect = 0.0
Identities = 1313/1313 (100%), Positives = 1313/1313 (100%)
Query: 19 GLTQEASVDLKNTGREEFLTAFLQNYQLAYSKAYPRLLISSLSESPASVSILSQADNTSK 78
GLTQEASVDLKNTGREEFLTAFLQNYQLAYSKAYPRLLISSLSESPASVSILSQADNTSK
Sbjct: 80 GLTQEASVDLKNTGREEFLTAFLQNYQLAYSKAYPRLLISSLSESPASVSILSQADNTSK 139
Query: 79 KVTVRPGESVMVNISAKAEMIGSKIFQHAVVIHSDYAISVQALNAKPDTAELTLLRPIQA 138
KVTVRPGESVMVNISAKAEMIGSKIFQHAVVIHSDYAISVQALNAKPDTAELTLLRPIQA
Sbjct: 140 KVTVRPGESVMVNISAKAEMIGSKIFQHAVVIHSDYAISVQALNAKPDTAELTLLRPIQA 199
Query: 139 LGTEYFVLTPPGTSARNVKEFAVVAGAAGASVSVTLKGSVTFNGKFYPAGDVLRVTLQPY 198
LGTEYFVLTPPGTSARNVKEFAVVAGAAGASVSVTLKGSVTFNGKFYPAGDVLRVTLQPY
Sbjct: 200 LGTEYFVLTPPGTSARNVKEFAVVAGAAGASVSVTLKGSVTFNGKFYPAGDVLRVTLQPY 259
Query: 199 NVAQLQSSVDLSGSKVTASSPVAVLSGHSCAQKHTTCNHVVEQLLPTSAWGTHYVVPTLA 258
NVAQLQSSVDLSGSKVTASSPVAVLSGHSCAQKHTTCNHVVEQLLPTSAWGTHYVVPTLA
Sbjct: 260 NVAQLQSSVDLSGSKVTASSPVAVLSGHSCAQKHTTCNHVVEQLLPTSAWGTHYVVPTLA 319
Query: 259 SQSRYDLAFVVASQATKLTYNHGGITGSRGLQAGDVVEFEVRPSWPLYLSANVGIQVLLF 318
SQSRYDLAFVVASQATKLTYNHGGITGSRGLQAGDVVEFEVRPSWPLYLSANVGIQVLLF
Sbjct: 320 SQSRYDLAFVVASQATKLTYNHGGITGSRGLQAGDVVEFEVRPSWPLYLSANVGIQVLLF 379
Query: 319 GTGAIRNEVTYDPYLVLIPDVAAYCPAYVVKSVPGCEGVALVVAQTKAISGLTIDGHAVG 378
GTGAIRNEVTYDPYLVLIPDVAAYCPAYVVKSVPGCEGVALVVAQTKAISGLTIDGHAVG
Sbjct: 380 GTGAIRNEVTYDPYLVLIPDVAAYCPAYVVKSVPGCEGVALVVAQTKAISGLTIDGHAVG 439
Query: 379 AKLTWEAVPGSEFSYAEVELGTADMIHTAEATTNLGLLTFGLAKAIGYATAADCGRTVLS 438
AKLTWEAVPGSEFSYAEVELGTADMIHTAEATTNLGLLTFGLAKAIGYATAADCGRTVLS
Sbjct: 440 AKLTWEAVPGSEFSYAEVELGTADMIHTAEATTNLGLLTFGLAKAIGYATAADCGRTVLS 499
Query: 439 PVEPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTM 498
PVEPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTM
Sbjct: 500 PVEPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTM 559
Query: 499 VELCSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSR 558
VELCSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSR
Sbjct: 560 VELCSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSR 619
Query: 559 LPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDP 618
LPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDP
Sbjct: 620 LPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDP 679
Query: 619 ADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLT 678
ADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLT
Sbjct: 680 ADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLT 739
Query: 679 KLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSP 738
KLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSP
Sbjct: 740 KLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSP 799
Query: 739 ANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASS 798
ANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASS
Sbjct: 800 ANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASS 859
Query: 799 CGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYP 858
CGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYP
Sbjct: 860 CGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYP 919
Query: 859 DRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVS 918
DRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVS
Sbjct: 920 DRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVS 979
Query: 919 YTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLT 978
YTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLT
Sbjct: 980 YTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLT 1039
Query: 979 VTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRP 1038
VTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRP
Sbjct: 1040 VTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRP 1099
Query: 1039 GCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLL 1098
GCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLL
Sbjct: 1100 GCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLL 1159
Query: 1099 PGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPV 1158
PGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPV
Sbjct: 1160 PGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPV 1219
Query: 1159 PGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQE 1218
PGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQE
Sbjct: 1220 PGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQE 1279
Query: 1219 GGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVL 1278
GGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVL
Sbjct: 1280 GGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVL 1339
Query: 1279 AQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTV 1331
AQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTV
Sbjct: 1340 AQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTV 1392
Score = 749 bits (1935), Expect = 0.0
Identities = 388/916 (42%), Positives = 516/916 (56%), Gaps = 33/916 (3%)
Query: 1645 CHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGC 1704
C G+ C + C+ GG+ C+ A C GDPHY +FDGR++D GTC+Y + C
Sbjct: 505 CEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVEL-C 563
Query: 1705 PGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGVLTA 1764
T L F+V KN++RG+ VSYV +VTV A ++S+ + E+G V V+ +
Sbjct: 564 SEDDT--LPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFV--LVDNQRSR 619
Query: 1765 LPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNP 1824
LPVS+++GR+ V Q +A++ FGL V+YDW+ ++ ++LP+ + VCGLCGN + +P
Sbjct: 620 LPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDP 679
Query: 1825 NNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLA 1884
+D + P+G LAP + SW+ D LC D C+ +CP C + + YEG CG L
Sbjct: 680 ADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLT 739
Query: 1885 SGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRA 1944
GPF CH + P F + CV D+C+ GG+R LC+ L++Y AC G+ + DWR+
Sbjct: 740 K-LDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRS 798
Query: 1945 QVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEG-PCVEGCQCDAGFVLSADRCV 2003
C ++CP NS YE+CGP CP SC A P+ C G PCVEGC C GFV S CV
Sbjct: 799 PANCPLSCPANSRYELCGPACPTSCNGAA---APSNCSGRPCVEGCVCLPGFVASGGACV 855
Query: 2004 PLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPA-SCGLGEVCGLLPSG 2062
P ++ CGC G G E WAD C + C C + C SC GE C + +G
Sbjct: 856 PASS-CGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSV-QNG 913
Query: 2063 QHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEH 2122
GC P CQ GDPHYV+ DG RFDF GTC YLL C G F V V NEH
Sbjct: 914 LLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSC-GQNAALPAFRVLVENEH 972
Query: 2123 RGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQL-DSLLHAHLSGADVVV 2181
RGSQ VSYTR+V ++ + + +P ++ VD V LPFQ D + G D VV
Sbjct: 973 RGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVV 1032
Query: 2182 TTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAG-------- 2233
T GL++ +D ++ V +VP++YA +LCGLCGN+N DPADDL GG A
Sbjct: 1033 RTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNS 1092
Query: 2234 WQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQG 2293
WQ GCG CP + Q+ + CG+++ GP CH + P +
Sbjct: 1093 WQEETRPGCGATEPGDCPKLDSLVAQQ-LQSKNECGILADPKGPFRECHSKLDPQGAVRD 1151
Query: 2294 CLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCP 2353
C+ D C + G G LC A+ATY AACQAAGA + WR + CPL CP HSHYE C CP
Sbjct: 1152 CVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCP 1211
Query: 2354 VSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPEC 2413
+SC L P GC S C EGCVCD GF LSG++C+P+ CGC+H G Y+P G+ FYPGP C
Sbjct: 1212 LSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGC 1271
Query: 2414 ERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYD 2473
+ C C GG V+C E ++CGPHE C+ G C A G C A+G HY T DGR +D
Sbjct: 1272 DSLCHCQEGGLVSC-ESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFD 1330
Query: 2474 LHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGD-----LQRLLVTVAGQVVSLAQGQ-QV 2527
G+C YVLAQ C +PG F+++ E A G+ + + V VA + L Q Q +V
Sbjct: 1331 FMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKV 1390
Query: 2528 TV--DGEAVALPVAVG 2541
TV DGE A + VG
Sbjct: 1391 TVRADGEQGARGLWVG 1406
Score = 749 bits (1933), Expect = 0.0
Identities = 394/957 (41%), Positives = 509/957 (53%), Gaps = 56/957 (5%)
Query: 834 TCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGS 893
+C Q C AG+RC V G GC + C+ GDPHY +FDGRR+D MGTC+Y +V
Sbjct: 504 SCEGMQ-CAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVEL 562
Query: 894 CGQNAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPF 953
C ++ LPAF V +NEHRGS+ VSY V V A V++ R G VLVD+ LP
Sbjct: 563 CSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPV 622
Query: 954 QAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADD 1013
++G+++V++ G AVV FGL VTYDW+ ++ +P+ + + +CGLCGN+NGDPADD
Sbjct: 623 SLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADD 682
Query: 1014 LALRGGGQAANALAFGNSWQEET-----RPGCGATEPGDCPKLDSLVAQQLQSKNECGIL 1068
G A +A+ F +SW+ + GC +CP AQ + CG+L
Sbjct: 683 FLTPDGALAPDAVEFASSWKLDDGDYLCEDGC----QNNCPACTPGQAQHYEGDRLCGML 738
Query: 1069 ADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRS 1128
GPF CH LDP+ + CVYD C++ G+ LC L+ YA AC G +V WRS
Sbjct: 739 TKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRS 798
Query: 1129 EELCPLSCPPHSHYEACSYGCPLSCGDLPVPGGC-GSECHEGCVCDEGFALSGESCLPLA 1187
CPLSCP +S YE C CP SC P C G C EGCVC GF SG +C+P +
Sbjct: 799 PANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPAS 858
Query: 1188 SCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGG-LVSC-ESSSCGPHEACQPSGGSLGCV 1245
SCGC QG PGQ + C C C V+C + SC E C G LGC
Sbjct: 859 SCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCY 918
Query: 1246 AVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRV 1305
TCQ SGDPHY +FDGRRFDFMGTC Y+L +CG L F VL EN G+ V
Sbjct: 919 PDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTV 978
Query: 1306 SVTRVITVQVANFTLRLEQRQ-WKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGL 1364
S TR + V+ + + + +V V+ V LP A+GQ++ + G D V+ TDFGL
Sbjct: 979 SYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGL 1038
Query: 1365 RVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSW-EEVV 1423
V YD V VP +Y + +CGLCGN+NGDP DD G QA NA FGNSW EE
Sbjct: 1039 TVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETR 1098
Query: 1424 PDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGP 1483
P P CP K + ++ Q + CG+L+ P GP CH +DPQG
Sbjct: 1099 PGCGATEPGDCP----------KLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGA 1148
Query: 1484 LKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCAD 1543
++DC++D CL G LC + Y +ACQAAG V PWR+E CP+ CPP+SHYE C+
Sbjct: 1149 VRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSY 1208
Query: 1544 TCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLI- 1602
C L C L P C C EGC CD GF +G++C+P+ CGC H G Y+ P QT
Sbjct: 1209 GCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPG 1268
Query: 1603 DNCRQQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQ 1662
C C C G + C+ SC P + CQPSGG L CV
Sbjct: 1269 PGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVG------------------- 1309
Query: 1663 GVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQ 1722
+TC GDPHY +FDGR+FDF GTC YVLA T C + GL F V +N
Sbjct: 1310 -------SSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQT-CG--TRPGLHRFAVLQENV 1359
Query: 1723 NRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQG 1779
GN VS RV+TV + + + + KV V +G A + V + +++ G
Sbjct: 1360 AWGNGRVSVTRVITVQVANFTLRLEQRQ-WKVTVRADGEQGARGLWVGGTQAALSPG 1415
Score = 585 bits (1508), Expect = e-166
Identities = 320/862 (37%), Positives = 433/862 (50%), Gaps = 37/862 (4%)
Query: 2045 CTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPC 2104
C C G+ C ++ G+ GC STA C+A GDPHY T DG R+D GTC Y + C
Sbjct: 505 CEGMQCAAGQRCQVV-GGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELC 563
Query: 2105 HGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPF 2164
F+V NEHRGS+ VSY VT++ Y+HS++L+ + VD LP
Sbjct: 564 SEDDT-LPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPV 622
Query: 2165 QL-DSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADD 2223
L + L + SG VV GL + +D D + L +PA + +CGLCGNYN DPADD
Sbjct: 623 SLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADD 682
Query: 2224 LKAVGGKPA--------GWQVG-GAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISAT 2274
G A W++ G C + CP+ CTP Q + + G CG+++
Sbjct: 683 FLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPA-CTPGQAQHYEGDRLCGMLTKL 741
Query: 2275 DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDF 2334
DGP A CH + P + + C+ D C V G LC ++ Y AC G +G+WR P
Sbjct: 742 DGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPAN 801
Query: 2335 CPLQCPAHSHYELCGDSCPVSCPSLSAPEGCESA-CREGCVCDAGFVLSGDTCVPVGQCG 2393
CPL CPA+S YELCG +CP SC +AP C C EGCVC GFV SG CVP CG
Sbjct: 802 CPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCG 861
Query: 2394 CLHDGRYYPLGEVFYPGPECERRCECGPGGH-VTCQEGAACGPHEECRLEDGVQACHATG 2452
C G G+ + C+RRC C H VTC++ +C E C +++G+ C+
Sbjct: 862 CTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDR 921
Query: 2453 CGRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGD-----L 2507
G C +G HY++ DGR +D G+C+Y+L C F +++E G
Sbjct: 922 FGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYT 981
Query: 2508 QRLLVTVAGQVVSLAQGQ--QVTVDGEAVALP--VAVGRVRVTAEGRNMVLQTTKGLRLL 2563
+ + V G V++ + QV VD LP A G+V+V +GR+ V++T GL +
Sbjct: 982 RAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVT 1041
Query: 2564 FDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKG 2623
+D +A + +PS + LCGLCGNFNG+ +DD L G A++ FG +W+ + G
Sbjct: 1042 YDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEE-TRPG 1100
Query: 2624 CGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQ 2683
CG P CP + +S CG L +P+GPF C + L P R CVYD C
Sbjct: 1101 CG-ATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLL 1159
Query: 2684 KGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSG 2743
G LC +LA Y AACQAAG V PWR++ CPL CP HSHY C+ C SC L
Sbjct: 1160 PGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPV 1219
Query: 2744 LTGCTTRCFEGCECDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTS-DCSERCSCSS 2802
GC + C EGC CD+ F LS C+P+ CGC H G Y P + C C C
Sbjct: 1220 PGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQE 1279
Query: 2803 SSGLTCQAAGCPPGRVCEVKAEARNCWAT-RGLCVLSVGANLTTFDGARGATTSPGVYEL 2861
++C+++ C P C+ + C A C S + TTFDG R VY L
Sbjct: 1280 GGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVL 1339
Query: 2862 SSRC---PG------LQNTIPW 2874
+ C PG LQ + W
Sbjct: 1340 AQTCGTRPGLHRFAVLQENVAW 1361
Score = 322 bits (825), Expect = 4e-87
Identities = 195/581 (33%), Positives = 281/581 (48%), Gaps = 39/581 (6%)
Query: 2429 EGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHP 2488
EG C + C++ G C A C A G HY T DGR YD+ G+CSY + ++C
Sbjct: 506 EGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSE 565
Query: 2489 KPGDEDFSIVLEKNAAGDLQRL---LVTVAG--QVVSLAQGQQ--VTVDGEAVALPVAV- 2540
FS+ + G + LVTV VSL +G+ V VD + LPV++
Sbjct: 566 DDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLS 625
Query: 2541 -GRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVL 2599
GR+RV G V++ GL + +D D L +S+P+ F+ ++CGLCGN+NG+ +DDF+
Sbjct: 626 EGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLT 685
Query: 2600 PNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGP 2659
P+G+ A F ++W+ C +GC CP C + YE + CG L GP
Sbjct: 686 PDGALAPDAVEFASSWKLDDGDYLCEDGC-QNNCPACTPGQAQHYEGDRLCGMLTKLDGP 744
Query: 2660 FATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPL 2719
FA C L P + QCVYDLC G++ LCR L+AY AC G++V WR+ + CPL
Sbjct: 745 FAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPL 804
Query: 2720 HCPAHSHYSICTRTCQGSCAALSGLTGCTTR-CFEGCECDDRFLLSQGVCIPVQDCGCTH 2778
CPA+S Y +C C SC + + C+ R C EGC C F+ S G C+P CGCT
Sbjct: 805 SCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGCTF 864
Query: 2779 NGRYLPVNSSLLTSD-CSERCSCSSSSG-LTCQ-AAGCPPGRVCEVKAEARNCWATR-GL 2834
G L + + C RC+C+ ++ +TC+ CP G C V+ C+ R G
Sbjct: 865 QGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGT 924
Query: 2835 CVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVGQV 2894
C S + +FDG R Y L C G +P +RV+ E + H ++ V
Sbjct: 925 CQGSGDPHYVSFDGRRFDFMGTCTYLLVGSC-GQNAALPAFRVLVENE--HRGSQTVSYT 981
Query: 2895 HIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTP----DGSL---------LVR 2941
+ +GV V +R + P + L + P DG + +VR
Sbjct: 982 RAVRVEA-------RGVKV-AVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVR 1033
Query: 2942 QKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTND 2982
G+ V N +V V + +A LCG CGNF+GD +D
Sbjct: 1034 TDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADD 1074
Score = 42.7 bits (99), Expect = 0.005
Identities = 49/190 (25%), Positives = 82/190 (43%), Gaps = 23/190 (12%)
Query: 2807 TCQAAGCPPGRVCEVKAEARNCWA-TRGLCVLSVGANLTTFDGARGATTSPGVYELSSRC 2865
+C+ C G+ C+V C A + +C + TTFDG R Y + C
Sbjct: 504 SCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELC 563
Query: 2866 PGLQNTIPWYRVVAEVQICHGKTEA-VGQVHIFFQDGMVTLTPNKG--VWVNGLRVDLPA 2922
+T+P + V A+ + + + VG V + V+LT + V V+ R LP
Sbjct: 564 SE-DDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLP- 621
Query: 2923 EKLASVSVSRTPDGSLLVRQKA---------GVQVWLGANGKVAVIVSNDHAGKLCGACG 2973
VS+S +G L V Q G+ V + ++A+ + ++CG CG
Sbjct: 622 -----VSLS---EGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCG 673
Query: 2974 NFDGDQTNDW 2983
N++GD +D+
Sbjct: 674 NYNGDPADDF 683
>gi|239757284 PREDICTED: similar to Fc fragment of IgG binding protein
[Homo sapiens]
Length = 593
Score = 1158 bits (2996), Expect = 0.0
Identities = 536/575 (93%), Positives = 537/575 (93%), Gaps = 36/575 (6%)
Query: 1336 MKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNG 1395
MKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNG
Sbjct: 1 MKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNG 60
Query: 1396 DPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKY 1455
DPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKY
Sbjct: 61 DPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKY 120
Query: 1456 QKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAA 1515
QKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAA
Sbjct: 121 QKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAA 180
Query: 1516 GGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYN 1575
GGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYN
Sbjct: 181 GGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYN 240
Query: 1576 GQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEHSCKPGQVCQPSGG 1635
GQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGK +VCQEHSCKPGQVCQPSGG
Sbjct: 241 GQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSCKPGQVCQPSGG 300
Query: 1636 ILSCVTK----------------------------------DPCHGVTCRPQETCKEQGG 1661
ILSCVTK DPCHGVTCRPQETCKEQGG
Sbjct: 301 ILSCVTKVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQETCKEQGG 360
Query: 1662 QGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKN 1721
QGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKN
Sbjct: 361 QGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKN 420
Query: 1722 QNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGAS 1781
QNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRV NGVLTALPVSVADGRISV QGAS
Sbjct: 421 QNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRV--NGVLTALPVSVADGRISVTQGAS 478
Query: 1782 KALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPI 1841
KALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPI
Sbjct: 479 KALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPI 538
Query: 1842 WGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEG 1876
WGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEG
Sbjct: 539 WGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEG 573
Score = 388 bits (996), Expect = e-107
Identities = 217/572 (37%), Positives = 285/572 (49%), Gaps = 78/572 (13%)
Query: 951 LPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDP 1010
LP A+GQ++ + G D V+ TDFGL V YD V VP +Y + +CGLCGN+NGDP
Sbjct: 3 LPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDP 62
Query: 1011 ADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCP----------KLDSLVAQQLQ 1060
DD G QA NA FGNSW EE P P CP K + ++ Q
Sbjct: 63 KDDFQKPNGSQAGNANEFGNSW-EEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQ 121
Query: 1061 SKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAG 1120
+ CG+L+ P GP CH +DPQG ++DC++D CL G LC + Y +ACQAAG
Sbjct: 122 KEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAG 181
Query: 1121 ATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSG 1180
V PWR+E CP+ CPP+SHYE C+ C L C L P C C EGC CD GF +G
Sbjct: 182 GHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNG 241
Query: 1181 ESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGG 1240
++C+P+ CGC H G Y+ P QT C C C G +V C+ SC P + CQPSGG
Sbjct: 242 QACVPIQQCGCYHNGVYYEPEQTVLI-DNCRQQCTCHAGKVVVCQEHSCKPGQVCQPSGG 300
Query: 1241 SLGCVAV-------------------------------------------GSSTCQASGD 1257
L CV TC+ G
Sbjct: 301 ILSCVTKVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQETCKEQGG 360
Query: 1258 -----PHYT------------TFDGRRFDFMGTCVYVLAQT-CG--TRPGLHRFAVLQEN 1297
P+Y +FDGR+FDF GTC YVLA T C + GL F V +N
Sbjct: 361 QGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKN 420
Query: 1298 VAWGNGRVSVTRVITVQVANFTLRLEQRQ-WKVTVNGVDMKLPVVLANGQIRASQHGSDV 1356
GN VS RV+TV + + + + KV VNGV LPV +A+G+I +Q S
Sbjct: 421 QNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKA 480
Query: 1357 VIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFG 1416
++ DFGL+V+YD + V VT+P +Y+ +CGLCGN + +P +D PNG+ A + +G
Sbjct: 481 LLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWG 540
Query: 1417 NSWEEVVPDSPCLPPT--PCPPGSEDCIPSHK 1446
SW D C CP ED + ++
Sbjct: 541 GSWRAPGWDPLCWDECRGSCPTCPEDRLEQYE 572
Score = 331 bits (848), Expect = 8e-90
Identities = 209/598 (34%), Positives = 286/598 (47%), Gaps = 83/598 (13%)
Query: 558 RLPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGD 617
+LPV L+ G++R Q G V+E FGL V YD + +++P + Q+CGLCGNYNGD
Sbjct: 2 KLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGD 61
Query: 618 PADDFLTPDGALAPDAVEFASSWK--LDDGDYL----CEDGCQNNCPA--CTPGQAQHYE 669
P DDF P+G+ A +A EF +SW+ + D L C G ++ P+ C P + Y+
Sbjct: 62 PKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQ 121
Query: 670 GDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELG 729
+ CG+L+ GP + CH +DP+ L+ C++DLC+ GG LC + AY AC G
Sbjct: 122 KEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAG 181
Query: 730 ISVGDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGC--------- 780
V WR+ CP+ CP NS YELC C C+ +AP C C EGC
Sbjct: 182 GHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDG-CAEGCQCDSGFLYN 240
Query: 781 --VCLP----GFVASGGACVPASS---------CGC------TFQGLQLAPGQ------- 812
C+P G +G P + C C Q PGQ
Sbjct: 241 GQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSCKPGQVCQPSGG 300
Query: 813 ------EVWADELCQRRCTCNGAT--------------------HQVTCRDKQSCPAGER 846
+V L Q GA H VTCR + E
Sbjct: 301 ILSCVTKVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQ------ET 354
Query: 847 CSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLV--GSCGQNA-ALPAF 903
C Q G C P+ TC GDPHY SFDGR+FDF GTC Y+L G G + L F
Sbjct: 355 CKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPF 414
Query: 904 RVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVF 963
V +N++RG+ VSY R V V A G +++ ++ G+V V+ VL LP ADG++ V
Sbjct: 415 TVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVT 474
Query: 964 RQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAA 1023
+ A++ DFGL V+YDWN RV +PSSY A+CGLCGN + +P +D G A
Sbjct: 475 QGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAP 534
Query: 1024 NALAFGNSWQEE-TRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHS 1080
+ +G SW+ P C G CP +Q + +E G L+D K C++
Sbjct: 535 SIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGLDE-GSLSDHKDKIFMCYT 591
Score = 325 bits (832), Expect = 5e-88
Identities = 198/583 (33%), Positives = 290/583 (49%), Gaps = 91/583 (15%)
Query: 1765 LPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNP 1824
LPV +A+G+I +Q S ++ DFGL+V+YD + V VT+P +Y+ +CGLCGN + +P
Sbjct: 3 LPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDP 62
Query: 1825 NNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPT----------CPEDRLEQY 1874
+D PNG+ A + +G SW D C CP CP + ++Y
Sbjct: 63 KDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPT--PCPPGSEDCIPSHKCPPELEKKY 120
Query: 1875 EGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQA 1934
+ FCG L+S TG P ++CH V P+ K C+ D+C+GGG+ ILC + +YV+ACQA
Sbjct: 121 QKEEFCGLLSSPTG-PLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQA 179
Query: 1935 AGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAG 1994
AG +E WR + C + CP NSHYE+C C C + L+ P C+ C EGCQCD+G
Sbjct: 180 AGGHVEPWRTETFCPMECPPNSHYELCADTCSLGC---SALSAPPQCQDGCAEGCQCDSG 236
Query: 1995 FVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGE 2054
F+ + CVP+ CGC+ NG Y+E D C Q C C G +VC SC G+
Sbjct: 237 FLYNGQACVPIQQ-CGCYHNGVYYEPEQTVLID-NCRQQCTC-HAGKVVVCQEHSCKPGQ 293
Query: 2055 VC----------------------------GLLPSGQ--------------HG--CQPVS 2070
VC +L +GQ HG C+P
Sbjct: 294 VCQPSGGILSCVTKVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQE 353
Query: 2071 T---------------AECQAWGDPHYVTLDGHRFDFQGTCEYLLSAP-CHG-PPLGAEN 2113
T A C WGDPHY + DG +FDFQGTC Y+L+ C G G
Sbjct: 354 TCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTP 413
Query: 2114 FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQL-DSLLHA 2172
FTVT N++RG+ AVSY R VT+ ++++ K++V+GV ALP + D +
Sbjct: 414 FTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISV 473
Query: 2173 HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA 2232
+ ++ GL +++D + V + +P++Y ++CGLCGN +++P +D G A
Sbjct: 474 TQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLA 533
Query: 2233 --------GWQVGGAQG-CGECVSKPCPSPCTPEQQESFGGPD 2266
W+ G C + CP+ C ++ E + G D
Sbjct: 534 PSIPIWGGSWRAPGWDPLCWDECRGSCPT-CPEDRLEQYEGLD 575
Score = 324 bits (831), Expect = 7e-88
Identities = 193/569 (33%), Positives = 274/569 (48%), Gaps = 101/569 (17%)
Query: 2170 LHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGG 2229
+ A G+DVV+ T GL +A+D +VR+ VP Y +CGLCGNYN DP DD +
Sbjct: 12 IRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQ---- 67
Query: 2230 KPAGWQVGGAQGCGECVSK-----------PCPS---------PCTPEQQESFGGPDACG 2269
KP G Q G A G + PCP C PE ++ + + CG
Sbjct: 68 KPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCG 127
Query: 2270 VISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEW 2329
++S+ GPL+ CH LV P + C+ D C G+ LC + YV+ACQAAG + W
Sbjct: 128 LLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPW 187
Query: 2330 RRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPV 2389
R FCP++CP +SHYELC D+C + C +LSAP C+ C EGC CD+GF+ +G CVP+
Sbjct: 188 RTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPI 247
Query: 2390 GQCGCLHDGRYY-PLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGV--- 2445
QCGC H+G YY P V C ++C C G V CQE +C P + C+ G+
Sbjct: 248 QQCGCYHNGVYYEPEQTVLI--DNCRQQCTCHAGKVVVCQE-HSCKPGQVCQPSGGILSC 304
Query: 2446 -------------------------------------QACHATGC------------GRC 2456
CH C G C
Sbjct: 305 VTKVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQETCKEQGGQGVC 364
Query: 2457 LAN--------GGIHYITLDGRVYDLHGSCSYVLAQVCHP---KPGDEDFSIVLEKNAAG 2505
L N G HY + DGR +D G+C+YVLA P G F++ + G
Sbjct: 365 LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRG 424
Query: 2506 D-----LQRLLVTVAGQVVSLAQGQ--QVTVDGEAVALPVAV--GRVRVTAEGRNMVLQT 2556
+ ++ + V G +S+ + + +V V+G ALPV+V GR+ VT +L
Sbjct: 425 NPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVA 484
Query: 2557 TKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWR 2616
GL++ +D + + +++PS + G +CGLCGN + N ++D V PNG+ A S+ +G +WR
Sbjct: 485 DFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWR 544
Query: 2617 APGSSKGCGEGCGPQGCPVCLAEETAPYE 2645
APG C + C CP C + YE
Sbjct: 545 APGWDPLCWDEC-RGSCPTCPEDRLEQYE 572
Score = 254 bits (649), Expect = 9e-67
Identities = 114/305 (37%), Positives = 173/305 (56%), Gaps = 15/305 (4%)
Query: 2536 LPVAV--GRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNW 2593
LPV + G++R + G ++V++T GLR+ +D ++ +++P + ++CGLCGN+NG+
Sbjct: 3 LPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDP 62
Query: 2594 SDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPV----CLAEETAP------ 2643
DDF PNGS A + FG +W C P CP C+ P
Sbjct: 63 KDDFQKPNGSQAGNANEFGNSWEEVVPDSPC---LPPTPCPPGSEDCIPSHKCPPELEKK 119
Query: 2644 YESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQA 2703
Y+ E CG L +P GP ++C ++ P + C++DLC G+ + LC ++ AY +ACQA
Sbjct: 120 YQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQA 179
Query: 2704 AGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLL 2763
AG V+PWRT++FCP+ CP +SHY +C TC C+ALS C C EGC+CD FL
Sbjct: 180 AGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLY 239
Query: 2764 SQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVKA 2823
+ C+P+Q CGC HNG Y ++L +C ++C+C + + CQ C PG+VC+
Sbjct: 240 NGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSCKPGQVCQPSG 299
Query: 2824 EARNC 2828
+C
Sbjct: 300 GILSC 304
Score = 187 bits (474), Expect = 2e-46
Identities = 93/238 (39%), Positives = 142/238 (59%), Gaps = 5/238 (2%)
Query: 436 VLSPVEPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCS 495
+LSP C G+ C + C+ GG+ C+ A C GDPHY +FDGR++D GTC+
Sbjct: 338 LLSP--DPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCN 395
Query: 496 YTMVEL-CSEDDT--LPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLV 552
Y + C T L F+V KN++RG+ VSYV +VTV A ++S+ + E+G V V
Sbjct: 396 YVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRV 455
Query: 553 DNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCG 612
+ + LPVS+++GR+ V Q +A++ FGL V+YDW+ ++ ++LP+ + VCGLCG
Sbjct: 456 NGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCG 515
Query: 613 NYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEG 670
N + +P +D + P+G LAP + SW+ D LC D C+ +CP C + + YEG
Sbjct: 516 NMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEG 573
Score = 32.0 bits (71), Expect = 9.5
Identities = 17/60 (28%), Positives = 33/60 (55%), Gaps = 1/60 (1%)
Query: 2925 LASVSVSRTPDGS-LLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTNDW 2983
LA+ + + GS +++ G++V V V V ++ ++CG CGN++GD +D+
Sbjct: 7 LANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDF 66
>gi|16554449 zonadhesin isoform 3 [Homo sapiens]
Length = 2812
Score = 876 bits (2264), Expect = 0.0
Identities = 568/1757 (32%), Positives = 818/1757 (46%), Gaps = 156/1757 (8%)
Query: 1136 CPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQG 1195
CPP++ YE+C+ CP SC P P CG C EGCVC+ GF S C+ +SC C +
Sbjct: 1044 CPPNARYESCA--CPASCKS-PRPS-CGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNN 1099
Query: 1196 TYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVA-VGSSTCQA 1254
Y+ PG ++ P C C C G V C+ S CG H CQ G GC G++TC
Sbjct: 1100 DYYEPGAEWF-SPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCLV 1158
Query: 1255 SGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQ 1314
GDPHY TFDGR F FMG C Y+LAQ CG F V +N G VS + V
Sbjct: 1159 YGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPF-FRVTAKNEEQGQEGVSCLSKVYVT 1217
Query: 1315 VANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYV 1374
+ T+ L + + + V G + LP + + G + G V ++T+FGLRV +D +
Sbjct: 1218 LPESTVTLLKGR-RTLVGGQQVTLPAIPSKGVFLGAS-GRFVELQTEFGLRVRWDGDQQL 1275
Query: 1375 RVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWE-EVVPDSPCLPPTP 1433
VTV Y ++CGLCGNY+G+ +D K +GS AG+ E GNSW+ + D C
Sbjct: 1276 YVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQ---- 1331
Query: 1434 CPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCL 1493
+ S C L+ FCG L GP +C V C+ D+C
Sbjct: 1332 ----KYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCG 1387
Query: 1494 GGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALS 1553
G +LC+++ + CQ AG V+PWR FCPM CPPNS Y LCA C C +
Sbjct: 1388 FQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSGF 1447
Query: 1554 APPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHN-GVYYEPEQTVLIDNCRQQCTCH 1612
+ C D C E C+C+ GF+ +G C+P QCGC H G Y++ + C++ C C
Sbjct: 1448 SGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCE 1507
Query: 1613 AGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEAT 1672
+ + CQ C R QE C +Q G C AT
Sbjct: 1508 SNNRIRCQPWRC--------------------------RAQEFCGQQDGIYGCHAQGAAT 1541
Query: 1673 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPA-VSY 1731
C GDPHY +FDG F GTC YVL P S + F V+ N+NRG VSY
Sbjct: 1542 CTASGDPHYLTFDGALHHFMGTCTYVLTR---PCWSRSQDSYFVVSATNENRGGILEVSY 1598
Query: 1732 VRVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVADFGL 1791
++ V V +IS+ + +V +NG ALPV +A GR+++ ++ LL +FGL
Sbjct: 1599 IKAVHVTVFDLSISLLRG----CKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGL 1654
Query: 1792 QVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAP-G 1850
QV YD + V+VT+PSSY G +CGLCGN + N +D + P+ LA G +W+ P
Sbjct: 1655 QVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPES 1714
Query: 1851 WDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLD 1910
+P C+ G +C E+ + C L + G PF+ CH VPP+S F CV
Sbjct: 1715 SEPGCF-LVGGKPSSCQENSMADAWNKN-CAILINPQG-PFSQCHQVVPPQSSFASCVHG 1771
Query: 1911 VCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCP 1970
C GD LC++L +Y + C AG WR + C + CP S Y C PCP +C
Sbjct: 1772 QCGTKGDTTALCRSLQAYASLCAQAGQA-PAWRNRTFCPMRCPPGSSYSPCSSPCPDTCS 1830
Query: 1971 SPAPLTTPAVCEG--PCVEGCQCDAGFVLSADRCVPLNNGCGCW-ANGTYHEAGSEFWAD 2027
S + P C PC E C+C G +LS CVPL CGC G+YH G ++ +
Sbjct: 1831 S---INNPRDCPKALPCAESCECQKGHILSGTSCVPLGQ-CGCTDPAGSYHPVGERWYTE 1886
Query: 2028 GTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDG 2087
TC++ C C ++ C ++C ++C L G C+ CQ G+ HYV+ DG
Sbjct: 1887 NTCTRLCTCSVHN-NITCFQSTCKPNQICWAL-DGLLRCRASGVGVCQLPGESHYVSFDG 1944
Query: 2088 HRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANE-HRGSQAVSYTRSVTLQIYNHSLTLS 2146
C +L CH P + F ++ +E G V + IY+ +TL
Sbjct: 1945 SNHSIPDACTLVLVKVCH-PAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQ 2003
Query: 2147 ARWPRKLQVDGVFVALPFQLDSLLHAHLSGADV--VVTTTSGLSLAFDGDSFVRLRVPAA 2204
++ ++ V LP + + + + + +V G+ + FDG+ + + +P
Sbjct: 2004 KG--HRVLINSKQVTLP-AISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTT 2060
Query: 2205 YAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCTP-------- 2256
Y +CG+CGN+N + D+L + A ++ K C
Sbjct: 2061 YYGKVCGMCGNFNDEEEDELMMPSDEVAN---SDSEFVNSWKDKDIDPSCQSLLVDEQQI 2117
Query: 2257 --EQQESFGGPDACGVI--------SATDGPL-APCHGLVPPAQYFQGCLLDACQVQGHP 2305
EQQE+ G + +A P+ A C + + C C+ G
Sbjct: 2118 PAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLY 2177
Query: 2306 GGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAP-EG 2364
LC A+ + A CQ+ G + WR FCPL+CPA+S Y C SC SC L EG
Sbjct: 2178 QALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEG 2237
Query: 2365 CE--SACREGCVCDAGFVLSGDTCVPVGQCGCLH-DGRYYPLGEVFYPGPECERRCECGP 2421
+ SAC EGC+C G+VLS D CVP QCGC G PLG+ + C +C C
Sbjct: 2238 AKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSG-CTEKCVC-T 2295
Query: 2422 GGHVTCQE-GAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCSY 2480
GG + C + G H + ++ C + +C G Y+T DG Y L G +Y
Sbjct: 2296 GGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTY 2355
Query: 2481 VLAQVCHPKPGDEDFSIVLEKNAAGD------LQRLLVTVAGQVVSLAQGQQVTVDGEAV 2534
VL + P + +V +N LQ ++ TV G V L G ++ V+ + +
Sbjct: 2356 VLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKM 2415
Query: 2535 ALPVAVGR-VRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNW 2593
A+P +RVT G+ + L T L + F G + ++S+PS + G + GLCGN++ N
Sbjct: 2416 AVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNR 2475
Query: 2594 SDDFVLPNGSAASSVETFGAAWRA-------------PGSSKGCGEGCGPQ-GCPV--CL 2637
+D +LP+G+ ++ TFG +W P +G G G + G V C
Sbjct: 2476 KNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECS 2535
Query: 2638 AEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCA---QKGDKAFLCRSL 2694
E+ A S +AC L +PQGPFA C ++P + CV DLC+ + + C+ L
Sbjct: 2536 PEQLAS-NSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVL 2594
Query: 2695 AAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQ-GSCAALSG-LTGCTTRCF 2752
+ + GV+ + + + + ++ + CQ G L G L G +
Sbjct: 2595 SGH-------GVSSR----------YHISELYDTLPSILCQPGRPRGLRGPLRGRLRQ-- 2635
Query: 2753 EGCECDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAG 2812
R L P+ DCGCT NG Y + SS LT DCS+RC+C+SS L C+
Sbjct: 2636 -----HPRLCLQWHPEPPLADCGCTSNGIYYQLGSSFLTEDCSQRCTCASSRILLCEPFS 2690
Query: 2813 CPPGRVCEVKAEARNCW 2829
C G VC + + C+
Sbjct: 2691 CRAGEVCTLGNHTQGCF 2707
Score = 842 bits (2175), Expect = 0.0
Identities = 556/1782 (31%), Positives = 795/1782 (44%), Gaps = 143/1782 (8%)
Query: 718 LSAYAQACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCV 777
+S +A + + +G + + CP N+RYE C ACP SC +P G C
Sbjct: 1017 MSPHAPSTPMTSVILGTTTTSRSSTERCPPNARYESC--ACPASCK---SPRPSCGPLCR 1071
Query: 778 EGCVCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRD 837
EGCVC PGF+ S C+ ASSC C + PG E W C C C + +V C+
Sbjct: 1072 EGCVCNPGFLFSDNHCIQASSCNCFYNNDYYEPGAE-WFSPNCTEHCRCWPGS-RVECQI 1129
Query: 838 KQSCPAGERCSVQNGLLGCYP-DRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQ 896
Q C C ++NG GC+P TC GDPHYV+FDGR F FMG CTY+L CG
Sbjct: 1130 SQ-CGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCG- 1187
Query: 897 NAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAA 956
N+ P FRV +NE +G + VS V V V + + + LV LP +
Sbjct: 1188 NSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLK--GRRTLVGGQQVTLPAIPS 1245
Query: 957 DGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLAL 1016
G V + GR ++T+FGL V +D + ++ V S+Y+ LCGLCGN++G+ +D
Sbjct: 1246 KG-VFLGASGRFVELQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLK 1304
Query: 1017 RGGGQAANALAFGNSWQ--EETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGP 1074
G A + GNSWQ ++ C + + P DS + + CG L D GP
Sbjct: 1305 LDGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGP 1364
Query: 1075 FRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPL 1134
F C + C+ D C G LC ++T CQ AG V PWR CP+
Sbjct: 1365 FETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPM 1424
Query: 1135 SCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVH- 1193
+CPP+S Y C+ CP +C C C E C C+ GF LSG C+P + CGC+H
Sbjct: 1425 ACPPNSKYSLCAKPCPDTCHSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHP 1484
Query: 1194 QGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQ 1253
G+Y G+ +Y PGC LC C+ + C+ C E C G GC A G++TC
Sbjct: 1485 AGSYFKVGERWYK-PGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCT 1543
Query: 1254 ASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITV 1313
ASGDPHY TFDG FMGTC YVL + C +R F V N G G + V+ + V
Sbjct: 1544 ASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRG-GILEVSYIKAV 1602
Query: 1314 QVANFTLRLE-QRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVY 1372
V F L + R KV +NG + LPV LA G++ + V++ T+FGL+V YD +
Sbjct: 1603 HVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSH 1662
Query: 1373 YVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPT 1432
V VTVP +Y Q+CGLCGNYN + DD +P+ AG++ + G +W+ +P+S
Sbjct: 1663 LVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWK--LPES------ 1714
Query: 1433 PCPPGSEDCIPSHKCPPELEKKYQKEEF---CGLLSSPTGPLSSCHKLVDPQGPLKDCIF 1489
PG C P ++ + + C +L +P GP S CH++V PQ C+
Sbjct: 1715 -SEPG---CFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVH 1770
Query: 1490 DLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGC 1549
C G+ + LC ++ AY S C A G WR TFCPM CPP S Y C+ C C
Sbjct: 1771 GQCGTKGDTTALCRSLQAYASLC-AQAGQAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTC 1829
Query: 1550 SALSAPPQCQDG--CAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEP--EQTVLIDNC 1605
S+++ P C CAE C+C G + +G +CVP+ QCGC Y P E+ + C
Sbjct: 1830 SSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTC 1889
Query: 1606 RQQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVC 1665
+ CTC + C + +CKP Q+C G+L C G GV
Sbjct: 1890 TRLCTCSVHNNITCFQSTCKPNQICWALDGLLRC------------------RASGVGV- 1930
Query: 1666 LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQ-NR 1724
C L G+ HY SFDG C VL P ++ L F ++ K++
Sbjct: 1931 -------CQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMA---LPFFKISAKHEKEE 1980
Query: 1725 GNPAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKAL 1784
G + V + +++ K RV +N LP +SV + ++
Sbjct: 1981 GGTEAFRLHEVYIDIYDAQVTLQKGH----RVLINSKQVTLPAISQIPGVSVKSSSIYSI 2036
Query: 1785 LVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGG 1844
+ G+QV +D N +++ +P++Y+G VCG+CGN + ++ + P+ +A S +
Sbjct: 2037 VNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVN 2096
Query: 1845 SWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGP-GFCGPL----------ASGTGGPFTT 1893
SW+ DP C+ + EQ E P G C A+ +
Sbjct: 2097 SWKDKDIDP----SCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQ 2152
Query: 1894 CHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCP 1953
C + + F C +C GG LC+AL ++ A CQ+ G+ WR C + CP
Sbjct: 2153 CASRIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECP 2212
Query: 1954 ENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCW- 2012
S Y C P C SC A C EGC C G+VLS D+CVP + CGC
Sbjct: 2213 AYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVP-RSQCGCKD 2271
Query: 2013 ANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQH-GCQPVST 2071
A+G G W C++ C C GG++ C C G C L + C +
Sbjct: 2272 AHGGSIPLGKS-WVSSGCTEKCVC--TGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKS 2328
Query: 2072 AECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYT 2131
+C +GDP Y+T DG + QG Y+L P G E V N+ ++ +
Sbjct: 2329 EQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFL 2388
Query: 2132 RSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAF 2191
+ V +Y + + L A +L V+ +A+P++ + L L G + + T L ++F
Sbjct: 2389 QEVITTVYGYKVQLQA--GLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSF 2446
Query: 2192 DGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA--------GWQV------- 2236
G + +P+ Y + GLCGNY+++ +D+ G W+V
Sbjct: 2447 GGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALL 2506
Query: 2237 -------GGAQGCGECVSKPC---PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVP 2286
+G G + S C+PEQ S AC V++ GP A CH V
Sbjct: 2507 RFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLAS-NSTQACRVLADPQGPFAACHQTVA 2565
Query: 2287 PAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYE 2346
P + + C+LD C Q P + CQ + H
Sbjct: 2566 PEPFQEHCVLDLCSAQD------PREQEEL-RCQVLSGH------------GVSSRYHIS 2606
Query: 2347 LCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEV 2406
D+ P P G R L P+ CGC +G YY LG
Sbjct: 2607 ELYDTLPSILCQPGRPRGLRGPLRGRLRQHPRLCLQWHPEPPLADCGCTSNGIYYQLGSS 2666
Query: 2407 FYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQAC 2448
F +C +RC C + C E +C E C L + Q C
Sbjct: 2667 FLT-EDCSQRCTCASSRILLC-EPFSCRAGEVCTLGNHTQGC 2706
Score = 816 bits (2109), Expect = 0.0
Identities = 536/1669 (32%), Positives = 761/1669 (45%), Gaps = 127/1669 (7%)
Query: 444 CEGMQCAAGQRCQVVGGKAGCVAES-TAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELC 502
C+ QC CQ+ G+ GC + TA C GDPHY TFDGR + MG C+Y + + C
Sbjct: 1127 CQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPC 1186
Query: 503 SEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVS 562
+ T P F V AKNE +G VS + V V +V+L +G LV Q+ LP
Sbjct: 1187 G-NSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGRR--TLVGGQQVTLPAI 1243
Query: 563 LSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDF 622
S+G + + SG ++ FGL V +D D QL +++ + + ++CGLCGNY+G+ +D
Sbjct: 1244 PSKG-VFLGASGRFVELQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDH 1302
Query: 623 LTPDGALAPDAVEFASSWKLD-DGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLD 681
L DG+ A D E +SW+ D D D C+ N P+C G CG L
Sbjct: 1303 LKLDGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTH 1362
Query: 682 GPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANC 741
GPF C + F + C+ D+C G + LC +S C + G +V WR P C
Sbjct: 1363 GPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFC 1422
Query: 742 PLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGC 801
P++CP NS+Y LC CP +C+ + CS R CVE C C PGFV SG C+P S CGC
Sbjct: 1423 PMACPPNSKYSLCAKPCPDTCHSGFSGMFCSDR-CVEACECNPGFVLSGLECIPRSQCGC 1481
Query: 802 TFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRF 861
E W C+ C C + +++ C+ + C A E C Q+G+ GC+
Sbjct: 1482 LHPAGSYFKVGERWYKPGCKELCVCE-SNNRIRCQPWR-CRAQEFCGQQDGIYGCHAQGA 1539
Query: 862 GTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGS-QTVSYT 920
TC SGDPHY++FDG FMGTCTY+L C + F V NE+RG VSY
Sbjct: 1540 ATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYI 1599
Query: 921 RAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVT 980
+AV V + +++ R +V+++ LP A G+V + ++ T+FGL V
Sbjct: 1600 KAVHVTVFDLSISLLRGC--KVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVR 1657
Query: 981 YDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQ--EETRP 1038
YD + V VPSSY LCGLCGN+N + DD A +++ G +W+ E + P
Sbjct: 1658 YDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEP 1717
Query: 1039 GCGAT--EPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRC 1096
GC +P C + A +KN C IL +P+GPF +CH + PQ + CV+ +C
Sbjct: 1718 GCFLVGGKPSSCQENSMADA---WNKN-CAILINPQGPFSQCHQVVPPQSSFASCVHGQC 1773
Query: 1097 LLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDL 1156
G + LC +L YA+ C AG WR+ CP+ CPP S Y CS CP +C +
Sbjct: 1774 GTKGDTTALCRSLQAYASLCAQAG-QAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSI 1832
Query: 1157 PVPGGC--GSECHEGCVCDEGFALSGESCLPLASCGCVH-QGTYHPPGQTFYPGPGCDSL 1213
P C C E C C +G LSG SC+PL CGC G+YHP G+ +Y C L
Sbjct: 1833 NNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRL 1892
Query: 1214 CHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGT 1273
C C ++C S+C P++ C G L C A G CQ G+ HY +FDG
Sbjct: 1893 CTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDA 1952
Query: 1274 CVYVLAQTCGTRPGLHRFAV--LQENVAWGNGRVSVTRV-ITVQVANFTLRLEQRQWKVT 1330
C VL + C L F + E G + V I + A TL Q+ +V
Sbjct: 1953 CTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTL---QKGHRVL 2009
Query: 1331 VNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLC 1390
+N + LP + + ++ G++V +D + + + +P YY ++CG+C
Sbjct: 2010 INSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMC 2069
Query: 1391 GNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPC---LPPTPCPPGSEDCIPSHKC 1447
GN+N + +D+ P+ A + +EF NSW++ D C L P + PS C
Sbjct: 2070 GNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNC 2129
Query: 1448 -PPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIH 1506
+L + +K E L +P + C +D L DC LC GG LC +
Sbjct: 2130 RAADLRRAREKCE--AALRAPV--WAQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQ 2185
Query: 1507 AYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQ-----DG 1561
A+ + CQ+ G WR +FCP+ECP S Y C +CS C L +C+
Sbjct: 2186 AFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDG--RCEGAKVPSA 2243
Query: 1562 CAEGCQCDSGFLYNGQACVPIQQCGCYH-NGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQ 1620
CAEGC C G++ + CVP QCGC +G ++ + C ++C C G + C
Sbjct: 2244 CAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVC-TGGAIQCG 2302
Query: 1621 EHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPH 1680
+ C G CQ +T D C+ + C ++GDP
Sbjct: 2303 DFRCPSGSHCQ--------LTSD----------------NSNSNCVSDKSEQCSVYGDPR 2338
Query: 1681 YHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAAL 1740
Y +FDG + QG YVL T V +G+ P V +N+ + +++ V
Sbjct: 2339 YLTFDGFSYRLQGRMTYVLIKT--VDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVY 2396
Query: 1741 GTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWR 1800
G + + + + VN A+P + + V + LV DF L VS+
Sbjct: 2397 GYKVQLQ----AGLELVVNNQKMAVPYR-PNEHLRVTLWGQRLYLVTDFELVVSFGGRKN 2451
Query: 1801 VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPL------ 1854
++LPS Y G V GLCGN D+N ND + P+G L ++ +G SW D L
Sbjct: 2452 AVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRA 2511
Query: 1855 --CWDECRGS---------CPTCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESF 1903
+E +G+ C ++L C LA GPF CH V PE F
Sbjct: 2512 IPAEEEGQGAELGLRTGLQVSECSPEQLAS-NSTQACRVLAD-PQGPFAACHQTVAPEPF 2569
Query: 1904 FKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGP 1963
+ CVLD+C R+ E+ R QV H
Sbjct: 2570 QEHCVLDLCSAQDPRE-------------------QEELRCQVLSGHGVSSRYHISELYD 2610
Query: 1964 PCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSE 2023
P+ P P GP + L PL + CGC +NG Y++ GS
Sbjct: 2611 TLPSILCQPG---RPRGLRGPLRGRLRQHPRLCLQWHPEPPLAD-CGCTSNGIYYQLGSS 2666
Query: 2024 FWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQH--GCQPVS 2070
F + CSQ C C L+C P SC GEVC L G H GC P S
Sbjct: 2667 FLTE-DCSQRCTCA-SSRILLCEPFSCRAGEVCTL---GNHTQGCFPES 2710
Score = 753 bits (1944), Expect = 0.0
Identities = 485/1510 (32%), Positives = 698/1510 (46%), Gaps = 134/1510 (8%)
Query: 1532 CPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNG 1591
CPPN+ YE CA C C S P C C EGC C+ GFL++ C+ C C++N
Sbjct: 1044 CPPNARYESCA--CPASCK--SPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNN 1099
Query: 1592 VYYEPEQTVLIDNCRQQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCR 1651
YYEP NC + C C G + CQ C VCQ G C P G
Sbjct: 1100 DYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGC---HPYAGT--- 1153
Query: 1652 PQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQG 1711
ATC ++GDPHY +FDGR F F G C Y+LA C G ST
Sbjct: 1154 -------------------ATCLVYGDPHYVTFDGRHFGFMGKCTYILAQP-C-GNSTDP 1192
Query: 1712 LTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVAD 1771
F VT KN+ +G VS + V V + +++ K R V G LP +
Sbjct: 1193 F--FRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGR----RTLVGGQQVTLPAIPSK 1246
Query: 1772 GRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFP 1831
G A G L +FGL+V +D + ++ VT+ S+Y G +CGLCGN D N +ND +
Sbjct: 1247 GVFLGASGRFVELQT-EFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKL 1305
Query: 1832 NGTLAPSIPIWGGSWRAP-GWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLASGTGGP 1890
+G+ A G SW+ D C + P+C GPGFCG L T GP
Sbjct: 1306 DGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVD-THGP 1364
Query: 1891 FTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEI 1950
F TC HV SFF C+LD+C G + +LC +++ CQ AG ++ WR C +
Sbjct: 1365 FETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPM 1424
Query: 1951 TCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCG 2010
CP NS Y +C PCP +C S + C CVE C+C+ GFVLS C+P + CG
Sbjct: 1425 ACPPNSKYSLCAKPCPDTCHSGF---SGMFCSDRCVEACECNPGFVLSGLECIPRSQ-CG 1480
Query: 2011 CW-ANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPV 2069
C G+Y + G ++ G C + C C + C P C E CG G +GC
Sbjct: 1481 CLHPAGSYFKVGERWYKPG-CKELCVC-ESNNRIRCQPWRCRAQEFCGQ-QDGIYGCHAQ 1537
Query: 2070 STAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGS-QAV 2128
A C A GDPHY+T DG F GTC Y+L+ PC + F V+ NE+RG V
Sbjct: 1538 GAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSY-FVVSATNENRGGILEV 1596
Query: 2129 SYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQL-DSLLHAHLSGADVVVTTTSGL 2187
SY ++V + +++ S++L K+ ++G VALP L + LS V++ T GL
Sbjct: 1597 SYIKAVHVTVFDLSISLLRGC--KVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGL 1654
Query: 2188 SLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAG--WQVGGAQGCGEC 2245
+ +DG V + VP++Y LCGLCGNYN + DD K AG Q+G A E
Sbjct: 1655 QVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPES 1714
Query: 2246 VSKPC------PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDAC 2299
C PS C + C ++ GP + CH +VPP F C+ C
Sbjct: 1715 SEPGCFLVGGKPSSCQENSMADAWNKN-CAILINPQGPFSQCHQVVPPQSSFASCVHGQC 1773
Query: 2300 QVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSL 2359
+G LC ++ Y + C AG Q WR FCP++CP S Y C CP +C S+
Sbjct: 1774 GTKGDTTALCRSLQAYASLCAQAG-QAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSI 1832
Query: 2360 SAPEGCESA--CREGCVCDAGFVLSGDTCVPVGQCGCLHD-GRYYPLGEVFYPGPECERR 2416
+ P C A C E C C G +LSG +CVP+GQCGC G Y+P+GE +Y C R
Sbjct: 1833 NNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRL 1892
Query: 2417 CECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHG 2476
C C ++TC + + C P++ C DG+ C A+G G C G HY++ DG + +
Sbjct: 1893 CTCSVHNNITCFQ-STCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPD 1951
Query: 2477 SCSYVLAQVCHPKPGDEDFSIVL--EKNAAGD----LQRLLVTVAGQVVSLAQGQQVTVD 2530
+C+ VL +VCHP F I EK G L + + + V+L +G +V ++
Sbjct: 1952 ACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLIN 2011
Query: 2531 GEAVALPVA--VGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGN 2588
+ V LP + V V + ++ G+++ FDG+ L + IP+ + G++CG+CGN
Sbjct: 2012 SKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGN 2071
Query: 2589 FNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNE 2648
FN D+ ++P+ A+S F +W+ C + + E+ P E E
Sbjct: 2072 FNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQS--------LLVDEQQIPAEQQE 2123
Query: 2649 ACGQLRNPQGP---------------------FATCQAVLSPSEYFRQCVYDLCAQKGDK 2687
NP G +A C + + + + C LC G
Sbjct: 2124 ------NPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLY 2177
Query: 2688 AFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGL--- 2744
LC++L A+ A CQ+ G+ WR SFCPL CPA+S Y+ C +C SC L G
Sbjct: 2178 QALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEG 2237
Query: 2745 TGCTTRCFEGCECDDRFLLSQGVCIPVQDCGCTH-NGRYLPVNSSLLTSDCSERCSCSSS 2803
+ C EGC C ++LS+ C+P CGC +G +P+ S ++S C+E+C C+
Sbjct: 2238 AKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGG 2297
Query: 2804 SGLTCQAAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYELSS 2863
+ + C CP G C++ ++ N CV + + R T Y L
Sbjct: 2298 A-IQCGDFRCPSGSHCQLTSDNSN-----SNCVSDKSEQCSVYGDPRYLTFDGFSYRLQG 2351
Query: 2864 RCP-GLQNTIPWYRVVAEVQICHGKTEA-VGQVHIFFQDGMVTLTPNKGVWVNGLRVDLP 2921
R L T+ E + G+ + + IF Q+ + T+ K GL + +
Sbjct: 2352 RMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVN 2411
Query: 2922 AEKLASVSVSRTPDGSLLVR---------QKAGVQVWLGANGKVAVIVSNDHAGKLCGAC 2972
+K+A V P+ L V + V G + + + + G + G C
Sbjct: 2412 NQKMA---VPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLC 2468
Query: 2973 GNFDGDQTND 2982
GN+D ++ ND
Sbjct: 2469 GNYDKNRKND 2478
Score = 646 bits (1667), Expect = 0.0
Identities = 392/1088 (36%), Positives = 549/1088 (50%), Gaps = 63/1088 (5%)
Query: 1952 CPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGC 2011
CP N+ YE C CPASC SP P P C EGC C+ GF+ S + C+ ++ C C
Sbjct: 1044 CPPNARYESCA--CPASCKSPRPSCGPL-----CREGCVCNPGFLFSDNHCIQASS-CNC 1095
Query: 2012 WANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVS- 2070
+ N Y+E G+E W C++ CRC PG + C + CG VC L +GQ+GC P +
Sbjct: 1096 FYNNDYYEPGAE-WFSPNCTEHCRCWPGS-RVECQISQCGTHTVCQL-KNGQYGCHPYAG 1152
Query: 2071 TAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSY 2130
TA C +GDPHYVT DG F F G C Y+L+ PC F VT NE +G + VS
Sbjct: 1153 TATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNST--DPFFRVTAKNEEQGQEGVSC 1210
Query: 2131 TRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLA 2190
V + + ++TL R+ V G V LP + SG V + T GL +
Sbjct: 1211 LSKVYVTLPESTVTLLKG--RRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVR 1268
Query: 2191 FDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAG--------WQVGGA--Q 2240
+DGD + + V + Y+ LCGLCGNY+ + +D + G PAG WQ Q
Sbjct: 1269 WDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQ 1328
Query: 2241 GCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQ 2300
C + PS C Q S GP CG + T GP C V A +F C+LD C
Sbjct: 1329 ECQKYQVVNSPS-CDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCG 1387
Query: 2301 VQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLS 2360
QG LC ++T CQ AG + WR P FCP+ CP +S Y LC CP +C S
Sbjct: 1388 FQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSGF 1447
Query: 2361 APEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHD-GRYYPLGEVFYPGPECERRCEC 2419
+ C C E C C+ GFVLSG C+P QCGCLH G Y+ +GE +Y P C+ C C
Sbjct: 1448 SGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYK-PGCKELCVC 1506
Query: 2420 GPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCS 2479
+ CQ C E C +DG+ CHA G C A+G HY+T DG ++ G+C+
Sbjct: 1507 ESNNRIRCQPW-RCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCT 1565
Query: 2480 YVLAQVCHPKPGDEDFSI-VLEKNAAGDLQ-----RLLVTVAGQVVSLAQGQQVTVDGEA 2533
YVL + C + D F + +N G L+ + VTV +SL +G +V ++G
Sbjct: 1566 YVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHR 1625
Query: 2534 VALPV--AVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNG 2591
VALPV A GRV + ++L T GL++ +DG + +++PS + G+LCGLCGN+N
Sbjct: 1626 VALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNN 1685
Query: 2592 NWSDDFVLPNGSAASSVETFGAAWRAPGSSK-GCG-EGCGPQGCPVCLAEETAPYESNEA 2649
N DD + P+ A GAAW+ P SS+ GC G P C E + N+
Sbjct: 1686 NSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSC----QENSMADAWNKN 1741
Query: 2650 CGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVK 2709
C L NPQGPF+ C V+ P F CV+ C KGD LCRSL AY + C AG A
Sbjct: 1742 CAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQA-P 1800
Query: 2710 PWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGC--TTRCFEGCECDDRFLLSQGV 2767
WR +FCP+ CP S YS C+ C +C++++ C C E CEC +LS
Sbjct: 1801 AWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTS 1860
Query: 2768 CIPVQDCGCTH-NGRYLPVNSSLLTSD-CSERCSCSSSSGLTCQAAGCPPGRVCEVKAEA 2825
C+P+ CGCT G Y PV T + C+ C+CS + +TC + C P ++C
Sbjct: 1861 CVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGL 1920
Query: 2826 RNCWATR-GLCVLSVGANLTTFDGARGATTSPGVYELSSRC-PGLQNTIPWYRVVAEVQI 2883
C A+ G+C L ++ +FDG+ + L C P + +P++++ A+ +
Sbjct: 1921 LRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAM--ALPFFKISAKHEK 1978
Query: 2884 CHGKTEA--VGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPA-EKLASVSVSRTPDGSLLV 2940
G TEA + +V+I D VTL V +N +V LPA ++ VSV + S +V
Sbjct: 1979 EEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYS-IV 2037
Query: 2941 RQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHDSQEKPA------MEK 2994
K GVQV N + + + + GK+CG CGNF+ ++ ++ ++ A +
Sbjct: 2038 NIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNS 2097
Query: 2995 WRAQDFSP 3002
W+ +D P
Sbjct: 2098 WKDKDIDP 2105
Score = 597 bits (1539), Expect = e-170
Identities = 392/1267 (30%), Positives = 580/1267 (45%), Gaps = 93/1267 (7%)
Query: 444 CEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCS 503
C+ +C A + C G GC A+ A C A GDPHY TFDG + MGTC+Y + C
Sbjct: 1514 CQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCW 1573
Query: 504 EDDTLPAFSVEAKNEHRGS-RRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVS 562
F V A NE+RG VSY+ V V + S+SL RG V+++ R LPV
Sbjct: 1574 SRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCK--VMLNGHRVALPVW 1631
Query: 563 LSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDF 622
L++GR+ + S ++ FGL V YD + +++P+ + Q+CGLCGNYN + DD
Sbjct: 1632 LAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDN 1691
Query: 623 LTPDGALAPDAVEFASSWKLDDGDYLCEDGC--QNNCPACTPGQAQHYEGDRLCGMLTKL 680
L PD LA D+++ ++WKL + E GC P+ + ++ C +L
Sbjct: 1692 LRPDRKLAGDSMQLGAAWKLPESS---EPGCFLVGGKPSSCQENSMADAWNKNCAILINP 1748
Query: 681 DGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPAN 740
GPF+ CH + P+ CV+ C G+ +LCR L AYA C + G + WR+
Sbjct: 1749 QGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQAPA-WRNRTF 1807
Query: 741 CPLSCPANSRYELCGPACPTSCNGAAAPSNC-SGRPCVEGCVCLPGFVASGGACVPASSC 799
CP+ CP S Y C CP +C+ P +C PC E C C G + SG +CVP C
Sbjct: 1808 CPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQC 1867
Query: 800 GCTFQGLQLAPGQEVWADE-LCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYP 858
GCT P E W E C R CTC+ + +TC + +C + C +GLL C
Sbjct: 1868 GCTDPAGSYHPVGERWYTENTCTRLCTCS-VHNNITCF-QSTCKPNQICWALDGLLRCRA 1925
Query: 859 DRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVS 918
G CQ G+ HYVSFDG CT +LV C ALP F++ ++E T +
Sbjct: 1926 SGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEA 1985
Query: 919 YT-RAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGL 977
+ V ++ +V +++ + +VL++ LP + V V ++V G+
Sbjct: 1986 FRLHEVYIDIYDAQVTLQKGH--RVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGV 2043
Query: 978 TVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQE-ET 1036
V +D N + ++P++Y +CG+CGNFN + D+L + A + F NSW++ +
Sbjct: 2044 QVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDI 2103
Query: 1037 RPGCGA---------TEPGDCPKLDSLVAQQLQSKNECGILADPKGP-FRECHSKLDPQG 1086
P C + E + P + A +++ +C A + P + +C S++D
Sbjct: 2104 DPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCE--AALRAPVWAQCASRIDLTP 2161
Query: 1087 AVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACS 1146
+ DC C G LC AL + A CQ+ G WR+ CPL CP +S Y C
Sbjct: 2162 FLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCL 2221
Query: 1147 YGCPLSCGDLPVPGGCG-----SECHEGCVCDEGFALSGESCLPLASCGC--VHQGTYHP 1199
C SC DL G C S C EGC+C G+ LS + C+P + CGC H G+ P
Sbjct: 2222 PSCSPSCWDLD--GRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSI-P 2278
Query: 1200 PGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQ--PSGGSLGCVAVGSSTCQASGD 1257
G+++ GC C C GG + C C CQ + CV+ S C GD
Sbjct: 2279 LGKSWVSS-GCTEKCVCT-GGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGD 2336
Query: 1258 PHYTTFDGRRFDFMGTCVYVLAQTCGTRP-GLHRFAVLQEN-VAWGNGRVSVTRVITVQV 1315
P Y TFDG + G YVL +T P G+ V N + + + VIT V
Sbjct: 2337 PRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITT-V 2395
Query: 1316 ANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVR 1375
+ ++L Q ++ VN M +P N +R + G + + TDF L V++
Sbjct: 2396 YGYKVQL-QAGLELVVNNQKMAVPY-RPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAV 2453
Query: 1376 VTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCP 1435
+++P Y + GLCGNY+ + K+D P+G+ N N FGNSWE D+ P P
Sbjct: 2454 ISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIP 2513
Query: 1436 P---------GSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKD 1486
G + +C PE + + C +L+ P GP ++CH+ V P+ +
Sbjct: 2514 AEEEGQGAELGLRTGLQVSECSPE-QLASNSTQACRVLADPQGPFAACHQTVAPEPFQEH 2572
Query: 1487 CIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCS 1546
C+ DLC CQ GH R H DT
Sbjct: 2573 CVLDLCSAQDPRE-------QEELRCQVLSGHGVSSRY------------HISELYDTLP 2613
Query: 1547 LGCSALSAPPQCQDGCAEGCQ--CDSGFLYNGQACV------PIQQCGCYHNGVYYEPEQ 1598
S L CQ G G + + + C+ P+ CGC NG+YY+
Sbjct: 2614 ---SIL-----CQPGRPRGLRGPLRGRLRQHPRLCLQWHPEPPLADCGCTSNGIYYQLGS 2665
Query: 1599 TVLIDNCRQQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKE 1658
+ L ++C Q+CTC + + ++C+ SC+ G+VC C + PC C+ C+E
Sbjct: 2666 SFLTEDCSQRCTCASSRILLCEPFSCRAGEVCTLGNHTQGCFPESPCLQNPCQNDGQCRE 2725
Query: 1659 QGGQGVC 1665
QG C
Sbjct: 2726 QGATFTC 2732
Score = 376 bits (965), Expect = e-103
Identities = 221/659 (33%), Positives = 316/659 (47%), Gaps = 25/659 (3%)
Query: 2338 QCPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHD 2397
+CP ++ YE C +CP SC S C CREGCVC+ GF+ S + C+ C C ++
Sbjct: 1043 RCPPNARYESC--ACPASCK--SPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYN 1098
Query: 2398 GRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHA-TGCGRC 2456
YY G ++ P C C C PG V CQ + CG H C+L++G CH G C
Sbjct: 1099 NDYYEPGAEWF-SPNCTEHCRCWPGSRVECQI-SQCGTHTVCQLKNGQYGCHPYAGTATC 1156
Query: 2457 LANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGD-----LQRLL 2511
L G HY+T DGR + G C+Y+LAQ C D F + + G L ++
Sbjct: 1157 LVYGDPHYVTFDGRHFGFMGKCTYILAQPC-GNSTDPFFRVTAKNEEQGQEGVSCLSKVY 1215
Query: 2512 VTVAGQVVSLAQGQQVTVDGEAVALPVAVGR-VRVTAEGRNMVLQTTKGLRLLFDGDAHL 2570
VT+ V+L +G++ V G+ V LP + V + A GR + LQT GLR+ +DGD L
Sbjct: 1216 VTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQL 1275
Query: 2571 LMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGP 2630
+++ S + G+LCGLCGN++GN +D + +GS A E G +W+ +
Sbjct: 1276 YVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQV 1335
Query: 2631 QGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFL 2690
P C + + CG+L + GPF TC + + +F C+ D+C +G + L
Sbjct: 1336 VNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLL 1395
Query: 2691 CRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTG--CT 2748
C ++ T CQ AG AVKPWR FCP+ CP +S YS+C + C +C SG +G C+
Sbjct: 1396 CTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCH--SGFSGMFCS 1453
Query: 2749 TRCFEGCECDDRFLLSQGVCIPVQDCGCTH-NGRYLPVNSSLLTSDCSERCSCSSSSGLT 2807
RC E CEC+ F+LS CIP CGC H G Y V C E C C S++ +
Sbjct: 1454 DRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRIR 1513
Query: 2808 CQAAGCPPGRVCEVKAEARNCWAT-RGLCVLSVGANLTTFDGARGATTSPGVYELSSRCP 2866
CQ C C + C A C S + TFDGA Y L+ C
Sbjct: 1514 CQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPC- 1572
Query: 2867 GLQNTIPWYRVVAEVQICHG---KTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAE 2923
+ Y VV+ G + + VH+ D ++L V +NG RV LP
Sbjct: 1573 -WSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVW 1631
Query: 2924 KLASVSVSRTPDGSLLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTND 2982
R +L+ G+QV + V V V + + G+LCG CGN++ + +D
Sbjct: 1632 LAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDD 1690
Score = 323 bits (829), Expect = 1e-87
Identities = 235/847 (27%), Positives = 357/847 (42%), Gaps = 87/847 (10%)
Query: 443 SCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELC 502
+C C Q C + G C A VC+ G+ HY +FDG + + C+ +V++C
Sbjct: 1902 TCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVC 1961
Query: 503 SEDDTLPAFSVEAKNE-HRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPV 561
LP F + AK+E G + V + Y V+L +G VL+++++ LP
Sbjct: 1962 HPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQKGH--RVLINSKQVTLPA 2019
Query: 562 SLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADD 621
+ V S ++V + G+ V +D + L + +P + +VCG+CGN+N + D+
Sbjct: 2020 ISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDE 2079
Query: 622 FLTPDGALAPDAVEFASSWKLDDGDYLCEDGC--QNNCPACTPGQAQHYEGDRLCGMLTK 679
+ P +A EF +SWK D D C+ + PA Q ++ G+ L +
Sbjct: 2080 LMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPA---EQQENPSGNCRAADLRR 2136
Query: 680 --------LDGP-FAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGI 730
L P +A C +D PFL C LC GG +LC+ L A+ C G+
Sbjct: 2137 AREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGL 2196
Query: 731 SVGDWRSPANCPLSCPANSRYELCGPACPTS-------CNGAAAPSNCSGRPCVEGCVCL 783
WR+ + CPL CPA S Y C P+C S C GA PS C EGC+C
Sbjct: 2197 KPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPS-----ACAEGCICQ 2251
Query: 784 PGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPA 843
PG+V S CVP S CGC P + W C +C C G + C D + CP+
Sbjct: 2252 PGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGA--IQCGDFR-CPS 2308
Query: 844 GERCSV--QNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALP 901
G C + N C D+ C GDP Y++FDG + G TY+L+ + LP
Sbjct: 2309 GSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVD---VLP 2365
Query: 902 --AFRVLVENEHRGSQTVS--YTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAAD 957
+LVE ++ S + + V G KV ++ +++V++ +P++ +
Sbjct: 2366 EGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGL--ELVVNNQKMAVPYRPNE 2423
Query: 958 GQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALR 1017
++V G+ + TDF L V++ +PS Y + GLCGN++ + +D+ L
Sbjct: 2424 -HLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLP 2482
Query: 1018 GGGQAANALAFGNSWQEETRP-------GCGATEPGDCPKLDSLVAQQL----------Q 1060
G N FGNSW+ +T A E G +L Q+
Sbjct: 2483 SGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASN 2542
Query: 1061 SKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLL--PGQSGPL-CDALATYAAACQ 1117
S C +LADP+GPF CH + P+ CV D C P + L C L+ + + +
Sbjct: 2543 STQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGHGVSSR 2602
Query: 1118 AAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFA 1177
+ ++ + L + C P P G
Sbjct: 2603 YHISELY----DTLPSILCQPGR------------------PRGLRGPLRGRLRQHPRLC 2640
Query: 1178 LSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQP 1237
L PLA CGC G Y+ G +F C C C ++ CE SC E C
Sbjct: 2641 LQWHPEPPLADCGCTSNGIYYQLGSSFLT-EDCSQRCTCASSRILLCEPFSCRAGEVCTL 2699
Query: 1238 SGGSLGC 1244
+ GC
Sbjct: 2700 GNHTQGC 2706
>gi|27881494 zonadhesin isoform 6 [Homo sapiens]
Length = 2721
Score = 856 bits (2211), Expect = 0.0
Identities = 539/1647 (32%), Positives = 772/1647 (46%), Gaps = 130/1647 (7%)
Query: 1136 CPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQG 1195
CPP++ YE+C+ CP SC P P CG C EGCVC+ GF S C+ +SC C +
Sbjct: 1044 CPPNARYESCA--CPASCKS-PRPS-CGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNN 1099
Query: 1196 TYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVA-VGSSTCQA 1254
Y+ PG ++ P C C C G V C+ S CG H CQ G GC G++TC
Sbjct: 1100 DYYEPGAEWF-SPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCLV 1158
Query: 1255 SGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQ 1314
GDPHY TFDGR F FMG C Y+LAQ CG F V +N G VS + V
Sbjct: 1159 YGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPF-FRVTAKNEEQGQEGVSCLSKVYVT 1217
Query: 1315 VANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYV 1374
+ T+ L + + + V G + LP + + G + G V ++T+FGLRV +D +
Sbjct: 1218 LPESTVTLLKGR-RTLVGGQQVTLPAIPSKGVFLGAS-GRFVELQTEFGLRVRWDGDQQL 1275
Query: 1375 RVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWE-EVVPDSPCLPPTP 1433
VTV Y ++CGLCGNY+G+ +D K +GS AG+ E GNSW+ + D C
Sbjct: 1276 YVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQ---- 1331
Query: 1434 CPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCL 1493
+ S C L+ FCG L GP +C V C+ D+C
Sbjct: 1332 ----KYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCG 1387
Query: 1494 GGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALS 1553
G +LC+++ + CQ AG V+PWR FCPM CPPNS Y LCA C C +
Sbjct: 1388 FQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSGF 1447
Query: 1554 APPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHN-GVYYEPEQTVLIDNCRQQCTCH 1612
+ C D C E C+C+ GF+ +G C+P QCGC H G Y++ + C++ C C
Sbjct: 1448 SGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCE 1507
Query: 1613 AGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEAT 1672
+ + CQ C R QE C +Q G C AT
Sbjct: 1508 SNNRIRCQPWRC--------------------------RAQEFCGQQDGIYGCHAQGAAT 1541
Query: 1673 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPA-VSY 1731
C GDPHY +FDG F GTC YVL P S + F V+ N+NRG VSY
Sbjct: 1542 CTASGDPHYLTFDGALHHFMGTCTYVLTR---PCWSRSQDSYFVVSATNENRGGILEVSY 1598
Query: 1732 VRVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVADFGL 1791
++ V V +IS+ + +V +NG ALPV +A GR+++ ++ LL +FGL
Sbjct: 1599 IKAVHVTVFDLSISLLRG----CKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGL 1654
Query: 1792 QVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAP-G 1850
QV YD + V+VT+PSSY G +CGLCGN + N +D + P+ LA G +W+ P
Sbjct: 1655 QVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPES 1714
Query: 1851 WDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLD 1910
+P C+ G +C E+ + C L + G PF+ CH VPP+S F CV
Sbjct: 1715 SEPGCF-LVGGKPSSCQENSMADAWNKN-CAILINPQG-PFSQCHQVVPPQSSFASCVHG 1771
Query: 1911 VCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCP 1970
C GD LC++L +Y + C AG WR + C + CP S Y C PCP +C
Sbjct: 1772 QCGTKGDTTALCRSLQAYASLCAQAGQA-PAWRNRTFCPMRCPPGSSYSPCSSPCPDTCS 1830
Query: 1971 SPAPLTTPAVCEG--PCVEGCQCDAGFVLSADRCVPLNNGCGCW-ANGTYHEAGSEFWAD 2027
S + P C PC E C+C G +LS CVPL CGC G+YH G ++ +
Sbjct: 1831 S---INNPRDCPKALPCAESCECQKGHILSGTSCVPLGQ-CGCTDPAGSYHPVGERWYTE 1886
Query: 2028 GTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDG 2087
TC++ C C ++ C ++C ++C L G C+ CQ G+ HYV+ DG
Sbjct: 1887 NTCTRLCTCSVHN-NITCFQSTCKPNQICWAL-DGLLRCRASGVGVCQLPGESHYVSFDG 1944
Query: 2088 HRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANE-HRGSQAVSYTRSVTLQIYNHSLTLS 2146
C +L CH P + F ++ +E G V + IY+ +TL
Sbjct: 1945 SNHSIPDACTLVLVKVCH-PAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQ 2003
Query: 2147 ARWPRKLQVDGVFVALPFQLDSLLHAHLSGADV--VVTTTSGLSLAFDGDSFVRLRVPAA 2204
++ ++ V LP + + + + + +V G+ + FDG+ + + +P
Sbjct: 2004 KG--HRVLINSKQVTLP-AISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTT 2060
Query: 2205 YAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCTP-------- 2256
Y +CG+CGN+N + D+L + A ++ K C
Sbjct: 2061 YYGKVCGMCGNFNDEEEDELMMPSDEVAN---SDSEFVNSWKDKDIDPSCQSLLVDEQQI 2117
Query: 2257 --EQQESFGGPDACGVI--------SATDGPL-APCHGLVPPAQYFQGCLLDACQVQGHP 2305
EQQE+ G + +A P+ A C + + C C+ G
Sbjct: 2118 PAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLY 2177
Query: 2306 GGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAP-EG 2364
LC A+ + A CQ+ G + WR FCPL+CPA+S Y C SC SC L EG
Sbjct: 2178 QALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEG 2237
Query: 2365 CE--SACREGCVCDAGFVLSGDTCVPVGQCGCLH-DGRYYPLGEVFYPGPECERRCECGP 2421
+ SAC EGC+C G+VLS D CVP QCGC G PLG+ + C +C C
Sbjct: 2238 AKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSG-CTEKCVC-T 2295
Query: 2422 GGHVTCQE-GAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCSY 2480
GG + C + G H + ++ C + +C G Y+T DG Y L G +Y
Sbjct: 2296 GGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTY 2355
Query: 2481 VLAQVCHPKPGDEDFSIVLEKNAAGD------LQRLLVTVAGQVVSLAQGQQVTVDGEAV 2534
VL + P + +V +N LQ ++ TV G V L G ++ V+ + +
Sbjct: 2356 VLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKM 2415
Query: 2535 ALPVAVGR-VRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNW 2593
A+P +RVT G+ + L T L + F G + ++S+PS + G + GLCGN++ N
Sbjct: 2416 AVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNR 2475
Query: 2594 SDDFVLPNGSAASSVETFGAAWRA-------------PGSSKGCGEGCGPQ-GCPV--CL 2637
+D +LP+G+ ++ TFG +W P +G G G + G V C
Sbjct: 2476 KNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECS 2535
Query: 2638 AEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCA---QKGDKAFLCRSL 2694
E+ A S +AC L +PQGPFA C ++P + CV DLC+ + + C+ L
Sbjct: 2536 PEQLAS-NSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVL 2594
Query: 2695 AAYTAACQAAGVAVKPWRTDSFCPLHC 2721
+ Y CQ AG A+ WR + C C
Sbjct: 2595 SGYAILCQEAGAALAGWRDRTLCESPC 2621
Score = 838 bits (2165), Expect = 0.0
Identities = 536/1676 (31%), Positives = 767/1676 (45%), Gaps = 125/1676 (7%)
Query: 718 LSAYAQACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCV 777
+S +A + + +G + + CP N+RYE C ACP SC +P G C
Sbjct: 1017 MSPHAPSTPMTSVILGTTTTSRSSTERCPPNARYESC--ACPASCK---SPRPSCGPLCR 1071
Query: 778 EGCVCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRD 837
EGCVC PGF+ S C+ ASSC C + PG E W C C C + +V C+
Sbjct: 1072 EGCVCNPGFLFSDNHCIQASSCNCFYNNDYYEPGAE-WFSPNCTEHCRCWPGS-RVECQI 1129
Query: 838 KQSCPAGERCSVQNGLLGCYP-DRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQ 896
Q C C ++NG GC+P TC GDPHYV+FDGR F FMG CTY+L CG
Sbjct: 1130 SQ-CGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCG- 1187
Query: 897 NAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAA 956
N+ P FRV +NE +G + VS V V V + + + LV LP +
Sbjct: 1188 NSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLK--GRRTLVGGQQVTLPAIPS 1245
Query: 957 DGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLAL 1016
G V + GR ++T+FGL V +D + ++ V S+Y+ LCGLCGN++G+ +D
Sbjct: 1246 KG-VFLGASGRFVELQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLK 1304
Query: 1017 RGGGQAANALAFGNSWQ--EETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGP 1074
G A + GNSWQ ++ C + + P DS + + CG L D GP
Sbjct: 1305 LDGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGP 1364
Query: 1075 FRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPL 1134
F C + C+ D C G LC ++T CQ AG V PWR CP+
Sbjct: 1365 FETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPM 1424
Query: 1135 SCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVH- 1193
+CPP+S Y C+ CP +C C C E C C+ GF LSG C+P + CGC+H
Sbjct: 1425 ACPPNSKYSLCAKPCPDTCHSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHP 1484
Query: 1194 QGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQ 1253
G+Y G+ +Y PGC LC C+ + C+ C E C G GC A G++TC
Sbjct: 1485 AGSYFKVGERWYK-PGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCT 1543
Query: 1254 ASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITV 1313
ASGDPHY TFDG FMGTC YVL + C +R F V N G G + V+ + V
Sbjct: 1544 ASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRG-GILEVSYIKAV 1602
Query: 1314 QVANFTLRLE-QRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVY 1372
V F L + R KV +NG + LPV LA G++ + V++ T+FGL+V YD +
Sbjct: 1603 HVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSH 1662
Query: 1373 YVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPT 1432
V VTVP +Y Q+CGLCGNYN + DD +P+ AG++ + G +W+ +P+S
Sbjct: 1663 LVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWK--LPES------ 1714
Query: 1433 PCPPGSEDCIPSHKCPPELEKKYQKEEF---CGLLSSPTGPLSSCHKLVDPQGPLKDCIF 1489
PG C P ++ + + C +L +P GP S CH++V PQ C+
Sbjct: 1715 -SEPG---CFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVH 1770
Query: 1490 DLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGC 1549
C G+ + LC ++ AY S C A G WR TFCPM CPP S Y C+ C C
Sbjct: 1771 GQCGTKGDTTALCRSLQAYASLC-AQAGQAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTC 1829
Query: 1550 SALSAPPQCQDG--CAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEP--EQTVLIDNC 1605
S+++ P C CAE C+C G + +G +CVP+ QCGC Y P E+ + C
Sbjct: 1830 SSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTC 1889
Query: 1606 RQQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVC 1665
+ CTC + C + +CKP Q+C G+L C G GV
Sbjct: 1890 TRLCTCSVHNNITCFQSTCKPNQICWALDGLLRC------------------RASGVGV- 1930
Query: 1666 LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQ-NR 1724
C L G+ HY SFDG C VL P ++ L F ++ K++
Sbjct: 1931 -------CQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMA---LPFFKISAKHEKEE 1980
Query: 1725 GNPAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKAL 1784
G + V + +++ K RV +N LP +SV + ++
Sbjct: 1981 GGTEAFRLHEVYIDIYDAQVTLQKGH----RVLINSKQVTLPAISQIPGVSVKSSSIYSI 2036
Query: 1785 LVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGG 1844
+ G+QV +D N +++ +P++Y+G VCG+CGN + ++ + P+ +A S +
Sbjct: 2037 VNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVN 2096
Query: 1845 SWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGP-GFCGPL----------ASGTGGPFTT 1893
SW+ DP C+ + EQ E P G C A+ +
Sbjct: 2097 SWKDKDIDP----SCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQ 2152
Query: 1894 CHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCP 1953
C + + F C +C GG LC+AL ++ A CQ+ G+ WR C + CP
Sbjct: 2153 CASRIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECP 2212
Query: 1954 ENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCW- 2012
S Y C P C SC A C EGC C G+VLS D+CVP + CGC
Sbjct: 2213 AYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVP-RSQCGCKD 2271
Query: 2013 ANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQH-GCQPVST 2071
A+G G W C++ C C GG++ C C G C L + C +
Sbjct: 2272 AHGGSIPLGKS-WVSSGCTEKCVC--TGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKS 2328
Query: 2072 AECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYT 2131
+C +GDP Y+T DG + QG Y+L P G E V N+ ++ +
Sbjct: 2329 EQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFL 2388
Query: 2132 RSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAF 2191
+ V +Y + + L A +L V+ +A+P++ + L L G + + T L ++F
Sbjct: 2389 QEVITTVYGYKVQLQA--GLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSF 2446
Query: 2192 DGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA--------GWQV------- 2236
G + +P+ Y + GLCGNY+++ +D+ G W+V
Sbjct: 2447 GGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALL 2506
Query: 2237 -------GGAQGCGECVSKPC---PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVP 2286
+G G + S C+PEQ S AC V++ GP A CH V
Sbjct: 2507 RFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLAS-NSTQACRVLADPQGPFAACHQTVA 2565
Query: 2287 PAQYFQGCLLDACQVQG---HPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQC 2339
P + + C+LD C Q C ++ Y CQ AGA L WR C C
Sbjct: 2566 PEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCESPC 2621
Score = 812 bits (2098), Expect = 0.0
Identities = 506/1555 (32%), Positives = 728/1555 (46%), Gaps = 100/1555 (6%)
Query: 444 CEGMQCAAGQRCQVVGGKAGCVAES-TAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELC 502
C+ QC CQ+ G+ GC + TA C GDPHY TFDGR + MG C+Y + + C
Sbjct: 1127 CQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPC 1186
Query: 503 SEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVS 562
+ T P F V AKNE +G VS + V V +V+L +G LV Q+ LP
Sbjct: 1187 G-NSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGRR--TLVGGQQVTLPAI 1243
Query: 563 LSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDF 622
S+G + + SG ++ FGL V +D D QL +++ + + ++CGLCGNY+G+ +D
Sbjct: 1244 PSKG-VFLGASGRFVELQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDH 1302
Query: 623 LTPDGALAPDAVEFASSWKLD-DGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLD 681
L DG+ A D E +SW+ D D D C+ N P+C G CG L
Sbjct: 1303 LKLDGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTH 1362
Query: 682 GPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANC 741
GPF C + F + C+ D+C G + LC +S C + G +V WR P C
Sbjct: 1363 GPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFC 1422
Query: 742 PLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGC 801
P++CP NS+Y LC CP +C+ + CS R CVE C C PGFV SG C+P S CGC
Sbjct: 1423 PMACPPNSKYSLCAKPCPDTCHSGFSGMFCSDR-CVEACECNPGFVLSGLECIPRSQCGC 1481
Query: 802 TFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRF 861
E W C+ C C + +++ C+ + C A E C Q+G+ GC+
Sbjct: 1482 LHPAGSYFKVGERWYKPGCKELCVCE-SNNRIRCQPWR-CRAQEFCGQQDGIYGCHAQGA 1539
Query: 862 GTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGS-QTVSYT 920
TC SGDPHY++FDG FMGTCTY+L C + F V NE+RG VSY
Sbjct: 1540 ATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYI 1599
Query: 921 RAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVT 980
+AV V + +++ R +V+++ LP A G+V + ++ T+FGL V
Sbjct: 1600 KAVHVTVFDLSISLLRGC--KVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVR 1657
Query: 981 YDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQ--EETRP 1038
YD + V VPSSY LCGLCGN+N + DD A +++ G +W+ E + P
Sbjct: 1658 YDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEP 1717
Query: 1039 GCGAT--EPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRC 1096
GC +P C + A +KN C IL +P+GPF +CH + PQ + CV+ +C
Sbjct: 1718 GCFLVGGKPSSCQENSMADA---WNKN-CAILINPQGPFSQCHQVVPPQSSFASCVHGQC 1773
Query: 1097 LLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDL 1156
G + LC +L YA+ C AG WR+ CP+ CPP S Y CS CP +C +
Sbjct: 1774 GTKGDTTALCRSLQAYASLCAQAG-QAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSI 1832
Query: 1157 PVPGGC--GSECHEGCVCDEGFALSGESCLPLASCGCVH-QGTYHPPGQTFYPGPGCDSL 1213
P C C E C C +G LSG SC+PL CGC G+YHP G+ +Y C L
Sbjct: 1833 NNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRL 1892
Query: 1214 CHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGT 1273
C C ++C S+C P++ C G L C A G CQ G+ HY +FDG
Sbjct: 1893 CTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDA 1952
Query: 1274 CVYVLAQTCGTRPGLHRFAV--LQENVAWGNGRVSVTRV-ITVQVANFTLRLEQRQWKVT 1330
C VL + C L F + E G + V I + A TL Q+ +V
Sbjct: 1953 CTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTL---QKGHRVL 2009
Query: 1331 VNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLC 1390
+N + LP + + ++ G++V +D + + + +P YY ++CG+C
Sbjct: 2010 INSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMC 2069
Query: 1391 GNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPC---LPPTPCPPGSEDCIPSHKC 1447
GN+N + +D+ P+ A + +EF NSW++ D C L P + PS C
Sbjct: 2070 GNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNC 2129
Query: 1448 -PPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIH 1506
+L + +K E L +P + C +D L DC LC GG LC +
Sbjct: 2130 RAADLRRAREKCE--AALRAPV--WAQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQ 2185
Query: 1507 AYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQ-----DG 1561
A+ + CQ+ G WR +FCP+ECP S Y C +CS C L +C+
Sbjct: 2186 AFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDG--RCEGAKVPSA 2243
Query: 1562 CAEGCQCDSGFLYNGQACVPIQQCGCYH-NGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQ 1620
CAEGC C G++ + CVP QCGC +G ++ + C ++C C G + C
Sbjct: 2244 CAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVC-TGGAIQCG 2302
Query: 1621 EHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPH 1680
+ C G CQ +T D C+ + C ++GDP
Sbjct: 2303 DFRCPSGSHCQ--------LTSD----------------NSNSNCVSDKSEQCSVYGDPR 2338
Query: 1681 YHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAAL 1740
Y +FDG + QG YVL T V +G+ P V +N+ + +++ V
Sbjct: 2339 YLTFDGFSYRLQGRMTYVLIKT--VDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVY 2396
Query: 1741 GTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWR 1800
G + + + + VN A+P + + V + LV DF L VS+
Sbjct: 2397 GYKVQLQ----AGLELVVNNQKMAVPYR-PNEHLRVTLWGQRLYLVTDFELVVSFGGRKN 2451
Query: 1801 VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPL------ 1854
++LPS Y G V GLCGN D+N ND + P+G L ++ +G SW D L
Sbjct: 2452 AVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRA 2511
Query: 1855 --CWDECRGS---------CPTCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESF 1903
+E +G+ C ++L C LA GPF CH V PE F
Sbjct: 2512 IPAEEEGQGAELGLRTGLQVSECSPEQLAS-NSTQACRVLAD-PQGPFAACHQTVAPEPF 2569
Query: 1904 FKGCVLDVCMGGGDR---DILCKALASYVAACQAAGVVIEDWRAQVGCEITCPEN 1955
+ CVLD+C R ++ C+ L+ Y CQ AG + WR + CE C +N
Sbjct: 2570 QEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCESPCLQN 2624
Score = 753 bits (1944), Expect = 0.0
Identities = 485/1510 (32%), Positives = 698/1510 (46%), Gaps = 134/1510 (8%)
Query: 1532 CPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNG 1591
CPPN+ YE CA C C S P C C EGC C+ GFL++ C+ C C++N
Sbjct: 1044 CPPNARYESCA--CPASCK--SPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNN 1099
Query: 1592 VYYEPEQTVLIDNCRQQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCR 1651
YYEP NC + C C G + CQ C VCQ G C P G
Sbjct: 1100 DYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGC---HPYAGT--- 1153
Query: 1652 PQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQG 1711
ATC ++GDPHY +FDGR F F G C Y+LA C G ST
Sbjct: 1154 -------------------ATCLVYGDPHYVTFDGRHFGFMGKCTYILAQP-C-GNSTDP 1192
Query: 1712 LTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVAD 1771
F VT KN+ +G VS + V V + +++ K R V G LP +
Sbjct: 1193 F--FRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGR----RTLVGGQQVTLPAIPSK 1246
Query: 1772 GRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFP 1831
G A G L +FGL+V +D + ++ VT+ S+Y G +CGLCGN D N +ND +
Sbjct: 1247 GVFLGASGRFVELQT-EFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKL 1305
Query: 1832 NGTLAPSIPIWGGSWRAP-GWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLASGTGGP 1890
+G+ A G SW+ D C + P+C GPGFCG L T GP
Sbjct: 1306 DGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVD-THGP 1364
Query: 1891 FTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEI 1950
F TC HV SFF C+LD+C G + +LC +++ CQ AG ++ WR C +
Sbjct: 1365 FETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPM 1424
Query: 1951 TCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCG 2010
CP NS Y +C PCP +C S + C CVE C+C+ GFVLS C+P + CG
Sbjct: 1425 ACPPNSKYSLCAKPCPDTCHSGF---SGMFCSDRCVEACECNPGFVLSGLECIPRSQ-CG 1480
Query: 2011 CW-ANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPV 2069
C G+Y + G ++ G C + C C + C P C E CG G +GC
Sbjct: 1481 CLHPAGSYFKVGERWYKPG-CKELCVC-ESNNRIRCQPWRCRAQEFCGQ-QDGIYGCHAQ 1537
Query: 2070 STAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGS-QAV 2128
A C A GDPHY+T DG F GTC Y+L+ PC + F V+ NE+RG V
Sbjct: 1538 GAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSY-FVVSATNENRGGILEV 1596
Query: 2129 SYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQL-DSLLHAHLSGADVVVTTTSGL 2187
SY ++V + +++ S++L K+ ++G VALP L + LS V++ T GL
Sbjct: 1597 SYIKAVHVTVFDLSISLLRGC--KVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGL 1654
Query: 2188 SLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAG--WQVGGAQGCGEC 2245
+ +DG V + VP++Y LCGLCGNYN + DD K AG Q+G A E
Sbjct: 1655 QVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPES 1714
Query: 2246 VSKPC------PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDAC 2299
C PS C + C ++ GP + CH +VPP F C+ C
Sbjct: 1715 SEPGCFLVGGKPSSCQENSMADAWNKN-CAILINPQGPFSQCHQVVPPQSSFASCVHGQC 1773
Query: 2300 QVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSL 2359
+G LC ++ Y + C AG Q WR FCP++CP S Y C CP +C S+
Sbjct: 1774 GTKGDTTALCRSLQAYASLCAQAG-QAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSI 1832
Query: 2360 SAPEGCESA--CREGCVCDAGFVLSGDTCVPVGQCGCLHD-GRYYPLGEVFYPGPECERR 2416
+ P C A C E C C G +LSG +CVP+GQCGC G Y+P+GE +Y C R
Sbjct: 1833 NNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRL 1892
Query: 2417 CECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHG 2476
C C ++TC + + C P++ C DG+ C A+G G C G HY++ DG + +
Sbjct: 1893 CTCSVHNNITCFQ-STCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPD 1951
Query: 2477 SCSYVLAQVCHPKPGDEDFSIVL--EKNAAGD----LQRLLVTVAGQVVSLAQGQQVTVD 2530
+C+ VL +VCHP F I EK G L + + + V+L +G +V ++
Sbjct: 1952 ACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLIN 2011
Query: 2531 GEAVALPVA--VGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGN 2588
+ V LP + V V + ++ G+++ FDG+ L + IP+ + G++CG+CGN
Sbjct: 2012 SKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGN 2071
Query: 2589 FNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNE 2648
FN D+ ++P+ A+S F +W+ C + + E+ P E E
Sbjct: 2072 FNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQS--------LLVDEQQIPAEQQE 2123
Query: 2649 ACGQLRNPQGP---------------------FATCQAVLSPSEYFRQCVYDLCAQKGDK 2687
NP G +A C + + + + C LC G
Sbjct: 2124 ------NPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLY 2177
Query: 2688 AFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGL--- 2744
LC++L A+ A CQ+ G+ WR SFCPL CPA+S Y+ C +C SC L G
Sbjct: 2178 QALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEG 2237
Query: 2745 TGCTTRCFEGCECDDRFLLSQGVCIPVQDCGCTH-NGRYLPVNSSLLTSDCSERCSCSSS 2803
+ C EGC C ++LS+ C+P CGC +G +P+ S ++S C+E+C C+
Sbjct: 2238 AKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGG 2297
Query: 2804 SGLTCQAAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYELSS 2863
+ + C CP G C++ ++ N CV + + R T Y L
Sbjct: 2298 A-IQCGDFRCPSGSHCQLTSDNSN-----SNCVSDKSEQCSVYGDPRYLTFDGFSYRLQG 2351
Query: 2864 RCP-GLQNTIPWYRVVAEVQICHGKTEA-VGQVHIFFQDGMVTLTPNKGVWVNGLRVDLP 2921
R L T+ E + G+ + + IF Q+ + T+ K GL + +
Sbjct: 2352 RMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVN 2411
Query: 2922 AEKLASVSVSRTPDGSLLVR---------QKAGVQVWLGANGKVAVIVSNDHAGKLCGAC 2972
+K+A V P+ L V + V G + + + + G + G C
Sbjct: 2412 NQKMA---VPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLC 2468
Query: 2973 GNFDGDQTND 2982
GN+D ++ ND
Sbjct: 2469 GNYDKNRKND 2478
Score = 646 bits (1667), Expect = 0.0
Identities = 392/1088 (36%), Positives = 549/1088 (50%), Gaps = 63/1088 (5%)
Query: 1952 CPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGC 2011
CP N+ YE C CPASC SP P P C EGC C+ GF+ S + C+ ++ C C
Sbjct: 1044 CPPNARYESCA--CPASCKSPRPSCGPL-----CREGCVCNPGFLFSDNHCIQASS-CNC 1095
Query: 2012 WANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVS- 2070
+ N Y+E G+E W C++ CRC PG + C + CG VC L +GQ+GC P +
Sbjct: 1096 FYNNDYYEPGAE-WFSPNCTEHCRCWPGS-RVECQISQCGTHTVCQL-KNGQYGCHPYAG 1152
Query: 2071 TAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSY 2130
TA C +GDPHYVT DG F F G C Y+L+ PC F VT NE +G + VS
Sbjct: 1153 TATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNST--DPFFRVTAKNEEQGQEGVSC 1210
Query: 2131 TRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLA 2190
V + + ++TL R+ V G V LP + SG V + T GL +
Sbjct: 1211 LSKVYVTLPESTVTLLKG--RRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVR 1268
Query: 2191 FDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAG--------WQVGGA--Q 2240
+DGD + + V + Y+ LCGLCGNY+ + +D + G PAG WQ Q
Sbjct: 1269 WDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQ 1328
Query: 2241 GCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQ 2300
C + PS C Q S GP CG + T GP C V A +F C+LD C
Sbjct: 1329 ECQKYQVVNSPS-CDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCG 1387
Query: 2301 VQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLS 2360
QG LC ++T CQ AG + WR P FCP+ CP +S Y LC CP +C S
Sbjct: 1388 FQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSGF 1447
Query: 2361 APEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHD-GRYYPLGEVFYPGPECERRCEC 2419
+ C C E C C+ GFVLSG C+P QCGCLH G Y+ +GE +Y P C+ C C
Sbjct: 1448 SGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYK-PGCKELCVC 1506
Query: 2420 GPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCS 2479
+ CQ C E C +DG+ CHA G C A+G HY+T DG ++ G+C+
Sbjct: 1507 ESNNRIRCQPW-RCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCT 1565
Query: 2480 YVLAQVCHPKPGDEDFSI-VLEKNAAGDLQ-----RLLVTVAGQVVSLAQGQQVTVDGEA 2533
YVL + C + D F + +N G L+ + VTV +SL +G +V ++G
Sbjct: 1566 YVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHR 1625
Query: 2534 VALPV--AVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNG 2591
VALPV A GRV + ++L T GL++ +DG + +++PS + G+LCGLCGN+N
Sbjct: 1626 VALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNN 1685
Query: 2592 NWSDDFVLPNGSAASSVETFGAAWRAPGSSK-GCG-EGCGPQGCPVCLAEETAPYESNEA 2649
N DD + P+ A GAAW+ P SS+ GC G P C E + N+
Sbjct: 1686 NSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSC----QENSMADAWNKN 1741
Query: 2650 CGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVK 2709
C L NPQGPF+ C V+ P F CV+ C KGD LCRSL AY + C AG A
Sbjct: 1742 CAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQA-P 1800
Query: 2710 PWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGC--TTRCFEGCECDDRFLLSQGV 2767
WR +FCP+ CP S YS C+ C +C++++ C C E CEC +LS
Sbjct: 1801 AWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTS 1860
Query: 2768 CIPVQDCGCTH-NGRYLPVNSSLLTSD-CSERCSCSSSSGLTCQAAGCPPGRVCEVKAEA 2825
C+P+ CGCT G Y PV T + C+ C+CS + +TC + C P ++C
Sbjct: 1861 CVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGL 1920
Query: 2826 RNCWATR-GLCVLSVGANLTTFDGARGATTSPGVYELSSRC-PGLQNTIPWYRVVAEVQI 2883
C A+ G+C L ++ +FDG+ + L C P + +P++++ A+ +
Sbjct: 1921 LRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAM--ALPFFKISAKHEK 1978
Query: 2884 CHGKTEA--VGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPA-EKLASVSVSRTPDGSLLV 2940
G TEA + +V+I D VTL V +N +V LPA ++ VSV + S +V
Sbjct: 1979 EEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYS-IV 2037
Query: 2941 RQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHDSQEKPA------MEK 2994
K GVQV N + + + + GK+CG CGNF+ ++ ++ ++ A +
Sbjct: 2038 NIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNS 2097
Query: 2995 WRAQDFSP 3002
W+ +D P
Sbjct: 2098 WKDKDIDP 2105
Score = 376 bits (965), Expect = e-103
Identities = 221/659 (33%), Positives = 316/659 (47%), Gaps = 25/659 (3%)
Query: 2338 QCPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHD 2397
+CP ++ YE C +CP SC S C CREGCVC+ GF+ S + C+ C C ++
Sbjct: 1043 RCPPNARYESC--ACPASCK--SPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYN 1098
Query: 2398 GRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHA-TGCGRC 2456
YY G ++ P C C C PG V CQ + CG H C+L++G CH G C
Sbjct: 1099 NDYYEPGAEWF-SPNCTEHCRCWPGSRVECQI-SQCGTHTVCQLKNGQYGCHPYAGTATC 1156
Query: 2457 LANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGD-----LQRLL 2511
L G HY+T DGR + G C+Y+LAQ C D F + + G L ++
Sbjct: 1157 LVYGDPHYVTFDGRHFGFMGKCTYILAQPC-GNSTDPFFRVTAKNEEQGQEGVSCLSKVY 1215
Query: 2512 VTVAGQVVSLAQGQQVTVDGEAVALPVAVGR-VRVTAEGRNMVLQTTKGLRLLFDGDAHL 2570
VT+ V+L +G++ V G+ V LP + V + A GR + LQT GLR+ +DGD L
Sbjct: 1216 VTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQL 1275
Query: 2571 LMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGP 2630
+++ S + G+LCGLCGN++GN +D + +GS A E G +W+ +
Sbjct: 1276 YVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQV 1335
Query: 2631 QGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFL 2690
P C + + CG+L + GPF TC + + +F C+ D+C +G + L
Sbjct: 1336 VNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLL 1395
Query: 2691 CRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTG--CT 2748
C ++ T CQ AG AVKPWR FCP+ CP +S YS+C + C +C SG +G C+
Sbjct: 1396 CTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCH--SGFSGMFCS 1453
Query: 2749 TRCFEGCECDDRFLLSQGVCIPVQDCGCTH-NGRYLPVNSSLLTSDCSERCSCSSSSGLT 2807
RC E CEC+ F+LS CIP CGC H G Y V C E C C S++ +
Sbjct: 1454 DRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRIR 1513
Query: 2808 CQAAGCPPGRVCEVKAEARNCWAT-RGLCVLSVGANLTTFDGARGATTSPGVYELSSRCP 2866
CQ C C + C A C S + TFDGA Y L+ C
Sbjct: 1514 CQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPC- 1572
Query: 2867 GLQNTIPWYRVVAEVQICHG---KTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAE 2923
+ Y VV+ G + + VH+ D ++L V +NG RV LP
Sbjct: 1573 -WSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVW 1631
Query: 2924 KLASVSVSRTPDGSLLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTND 2982
R +L+ G+QV + V V V + + G+LCG CGN++ + +D
Sbjct: 1632 LAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDD 1690
Score = 326 bits (836), Expect = 2e-88
Identities = 220/739 (29%), Positives = 330/739 (44%), Gaps = 64/739 (8%)
Query: 443 SCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELC 502
+C C Q C + G C A VC+ G+ HY +FDG + + C+ +V++C
Sbjct: 1902 TCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVC 1961
Query: 503 SEDDTLPAFSVEAKNE-HRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPV 561
LP F + AK+E G + V + Y V+L +G VL+++++ LP
Sbjct: 1962 HPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQKGH--RVLINSKQVTLPA 2019
Query: 562 SLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADD 621
+ V S ++V + G+ V +D + L + +P + +VCG+CGN+N + D+
Sbjct: 2020 ISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDE 2079
Query: 622 FLTPDGALAPDAVEFASSWKLDDGDYLCEDGC--QNNCPACTPGQAQHYEGDRLCGMLTK 679
+ P +A EF +SWK D D C+ + PA Q ++ G+ L +
Sbjct: 2080 LMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPA---EQQENPSGNCRAADLRR 2136
Query: 680 --------LDGP-FAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGI 730
L P +A C +D PFL C LC GG +LC+ L A+ C G+
Sbjct: 2137 AREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGL 2196
Query: 731 SVGDWRSPANCPLSCPANSRYELCGPACPTS-------CNGAAAPSNCSGRPCVEGCVCL 783
WR+ + CPL CPA S Y C P+C S C GA PS C EGC+C
Sbjct: 2197 KPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPS-----ACAEGCICQ 2251
Query: 784 PGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPA 843
PG+V S CVP S CGC P + W C +C C G + C D + CP+
Sbjct: 2252 PGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGA--IQCGDFR-CPS 2308
Query: 844 GERCSV--QNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALP 901
G C + N C D+ C GDP Y++FDG + G TY+L+ + LP
Sbjct: 2309 GSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVD---VLP 2365
Query: 902 --AFRVLVENEHRGSQTVS--YTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAAD 957
+LVE ++ S + + V G KV ++ +++V++ +P++ +
Sbjct: 2366 EGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGL--ELVVNNQKMAVPYRPNE 2423
Query: 958 GQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALR 1017
++V G+ + TDF L V++ +PS Y + GLCGN++ + +D+ L
Sbjct: 2424 -HLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLP 2482
Query: 1018 GGGQAANALAFGNSWQEETRP-------GCGATEPGDCPKLDSLVAQQL----------Q 1060
G N FGNSW+ +T A E G +L Q+
Sbjct: 2483 SGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASN 2542
Query: 1061 SKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLL--PGQSGPL-CDALATYAAACQ 1117
S C +LADP+GPF CH + P+ CV D C P + L C L+ YA CQ
Sbjct: 2543 STQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQ 2602
Query: 1118 AAGATVHPWRSEELCPLSC 1136
AGA + WR LC C
Sbjct: 2603 EAGAALAGWRDRTLCESPC 2621
>gi|134268640 tectorin alpha precursor [Homo sapiens]
Length = 2155
Score = 848 bits (2191), Expect = 0.0
Identities = 508/1575 (32%), Positives = 743/1575 (47%), Gaps = 121/1575 (7%)
Query: 444 CEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCS 503
C+ C+ + C+ G C A T+ C G+PHY TFDG + G+C+Y + C
Sbjct: 294 CQEASCSPYEVCEPKGKFFYCSAVETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCL 353
Query: 504 EDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSL 563
+ +LP FSVEAKNEHR VS+V ++V + + + +G G V V++ + LPV+L
Sbjct: 354 QTSSLPFFSVEAKNEHRRGSAVSWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTL 413
Query: 564 SEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFL 623
G +++YQSG VE FGL+VT+D ++S+P + + CGLCGNYN +P DDFL
Sbjct: 414 DLGTVKIYQSGISTAVETDFGLLVTFDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFL 473
Query: 624 TPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGP 683
PDG A ++ SW++ D+ C+ GC +NC C Y G CG L K DGP
Sbjct: 474 RPDGRPAMSVLDLGESWRVYHADWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGP 533
Query: 684 FAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANC-- 741
C +DP F+ CVYDLC V LC+ + AYA C LGI +GDWR+ C
Sbjct: 534 LWECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVS 593
Query: 742 PLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGC 801
+ CP+ S Y +C +CP +C+ A NC+ PC EGC C GFV S CVP CGC
Sbjct: 594 TVQCPSFSHYSVCTSSCPDTCSDLTASRNCA-TPCTEGCECNQGFVLSTSQCVPLHKCGC 652
Query: 802 TFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRF 861
F G G+ WA C +C C V C +K +C +GE C+V++G GC+P R
Sbjct: 653 DFDGHYYTMGEFFWATANCTVQCLCEEG-GDVYCFNK-TCGSGEVCAVEDGYQGCFPKRE 710
Query: 862 GTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTR 921
C S + +FDG + F +Y L+ +C + P + + N+ + ++ R
Sbjct: 711 TVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPER---PEYLEIDINKKKPDAGPAWLR 767
Query: 922 AVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTY 981
+R+ +V + +V ++ LPF G+++++R V + +TV Y
Sbjct: 768 GLRILVADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVESKGVVTVQY 827
Query: 982 DWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQ--EETRPG 1039
+ ++ ++Y GLCG +N + +D+ L G N F SW EE G
Sbjct: 828 SDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTFEEICNG 887
Query: 1040 CGATEPGDCPKL---DSLVAQQLQSKNECGILADP-KGPFRECHSKLDPQGAVRDCVYDR 1095
E GD K DS + + +S++ CGI+ DP F ECH ++ R C++
Sbjct: 888 ----ECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRL 943
Query: 1096 CLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGD 1155
C G LCD++A YA+AC+ A V PWR+ + CPL CP +SH+E C C +C
Sbjct: 944 CQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEEC-ITCTETCET 1002
Query: 1156 LPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCH 1215
L + C C EGC CDEG+AL G C+ + CGC +G +TF+ C C+
Sbjct: 1003 LTLGPICVDSCSEGCQCDEGYALLGSQCVTRSECGCNFEGHQLATNETFWVDLDCQIFCY 1062
Query: 1216 CQ-EGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTC 1274
C V CE+ C E C GG C A ++C SG HY TFDG FDF +C
Sbjct: 1063 CSGTDNRVHCETIPCKDDEYCMEEGGLYYCQARTDASCIVSGYGHYLTFDGFPFDFQTSC 1122
Query: 1275 VYVLAQTCGTRP---GLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQR-QWKVT 1330
+L T G+RP +F V +N + + V V +++ + + + V
Sbjct: 1123 PLILC-TTGSRPSSDSFPKFVVTAKNEDRDPSLALWVKQVDVTVFGYSIVIHRAYKHTVL 1181
Query: 1331 VNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLC 1390
VN + LP+ L G+I G VV+ETDFGL+V YD ++ +TVP + GLC
Sbjct: 1182 VNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYDWKTFLSITVPRSMQNSTYGLC 1241
Query: 1391 GNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPE 1450
G YNG+P DD + P G A + NEFG SW + T C G D PS C +
Sbjct: 1242 GRYNGNPDDDLEMPMGLLASSVNEFGQSWVK--------RDTFCQVGCGDRCPS--C-AK 1290
Query: 1451 LEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVS 1510
+E + ++ C L+ + S CH V+P K+C+FD C+ GG + CS + Y S
Sbjct: 1291 VEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGAVQTACSWLQNYAS 1350
Query: 1511 ACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDS 1570
CQ G V WR T C + CPPNSHYE C C C+A+ C C EGC CD+
Sbjct: 1351 TCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCAAIRLKSDCSHYCVEGCHCDA 1410
Query: 1571 GFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEHSCKPGQVC 1630
G++ NG++C+ CGCY +G YYEP+Q +C ++C C + C CK + C
Sbjct: 1411 GYVLNGKSCILPHSCGCYSDGKYYEPKQLFWNSDCTRRCRCFRRNVIQCDPRQCKSDEEC 1470
Query: 1631 QPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFD 1690
G+ C + + C GG GV + +FDG
Sbjct: 1471 ALRNGVRGCFSTKTSY---------CLAAGG-GV----------------FRTFDGAFLR 1504
Query: 1691 FQGTCNYVLAT--TGCPGVSTQGLTPFTV-TTKNQNRGNPAVSYVRVVTVAALGTNISIH 1747
F C +VL+T P +S Q + F + N +P Y+ + N
Sbjct: 1505 FPANCAFVLSTICQKLPDISFQLIINFDKWSAPNLTIISPVYFYINEEQILINDRN---- 1560
Query: 1748 KDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVADFG--LQVSYDWNWRVDVTL 1805
V VNG +P ++ +S+ LV D +Q+ Y+ + +++
Sbjct: 1561 -------TVKVNGTQVNVPFITG---LATKIYSSEGFLVIDTSPDIQIYYNGFNVIKISI 1610
Query: 1806 PSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPT 1865
VCGLCGN + + +D V G S + SW+ G + R P+
Sbjct: 1611 SERLQNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKTNGM------QKRPLAPS 1664
Query: 1866 CPEDRLEQY------------EGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDVCM 1913
C E + QY +G G+C L + G F C+ + P F++ C LD C
Sbjct: 1665 CNELQFSQYAAMCDNVHIQKMQGDGYCLKL-TDMKGFFQPCYGLLDPLPFYESCYLDGCY 1723
Query: 1914 GGGDRDILCKALASYVAACQAAGVVIEDWRAQVGC--------------EITCPENSHYE 1959
+ LC +LA+Y AC++ G++ +W + C TC + E
Sbjct: 1724 -SHKKFQLCGSLAAYGEACRSFGILSTEWIEKENCSGVVEDPCVGADCPNRTCELGNGRE 1782
Query: 1960 VCGPPCPASCPSPAP 1974
+CG C P P
Sbjct: 1783 LCG------CIEPPP 1791
Score = 843 bits (2179), Expect = 0.0
Identities = 500/1582 (31%), Positives = 736/1582 (46%), Gaps = 90/1582 (5%)
Query: 781 VCLPG---FVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRD 837
V +PG F G PA+ GCT +G L G+ W D C +C C +++ C++
Sbjct: 239 VNVPGRWAFKVDGKEIDPAN--GCTSRGQFLRRGEVFWDDLNCTVKCRCLDFNNEIYCQE 296
Query: 838 KQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQN 897
SC E C + C TC G+PHY +FDG F F G+C YLL C Q
Sbjct: 297 -ASCSPYEVCEPKGKFFYCSAVETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQT 355
Query: 898 AALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAAD 957
++LP F V +NEHR VS+ + + VE G K+ + + G+V V+D++ LP
Sbjct: 356 SSLPFFSVEAKNEHRRGSAVSWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDL 415
Query: 958 GQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALR 1017
G V++++ G V TDFGL VT+D + VP SY + CGLCGN+N +P DD
Sbjct: 416 GTVKIYQSGISTAVETDFGLLVTFDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRP 475
Query: 1018 GGGQAANALAFGNSWQ-EETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFR 1076
G A + L G SW+ C + +C + D+ + CG L GP
Sbjct: 476 DGRPAMSVLDLGESWRVYHADWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGPLW 535
Query: 1077 ECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELC--PL 1134
EC + +DP V CVYD C + LC A+ YA CQA G + WR++ C +
Sbjct: 536 ECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTV 595
Query: 1135 SCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQ 1194
CP SHY C+ CP +C DL C + C EGC C++GF LS C+PL CGC
Sbjct: 596 QCPSFSHYSVCTSSCPDTCSDLTASRNCATPCTEGCECNQGFVLSTSQCVPLHKCGCDFD 655
Query: 1195 GTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQA 1254
G Y+ G+ F+ C C C+EGG V C + +CG E C G GC + C
Sbjct: 656 GHYYTMGEFFWATANCTVQCLCEEGGDVYCFNKTCGSGEVCAVEDGYQGCFPKRETVCLL 715
Query: 1255 SGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQ 1314
S + TFDG + F Y L +TC RP + + N + + R + +
Sbjct: 716 SQNQVLHTFDGASYAFPSEFSYTLLKTCPERP---EYLEIDINKKKPDAGPAWLRGLRIL 772
Query: 1315 VANFTLRLEQ-RQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYY 1373
VA+ +++ +V +NG +++LP +G++ ++ + +E+ + V Y +
Sbjct: 773 VADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVESKGVVTVQYSDIGL 832
Query: 1374 VRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSW---EEVVPDSPCLP 1430
+ + + Y+ GLCG YN + D+F PNG N F SW EE+
Sbjct: 833 LYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTFEEI-------- 884
Query: 1431 PTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPT-GPLSSCHKLVDPQGPLKDCIF 1489
C D + + EL K Y+ CG+++ P+ CH +V+ + C+F
Sbjct: 885 ---CNGECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLF 941
Query: 1490 DLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGC 1549
LC GGN S LC ++ Y SAC+ A V PWRT FCP+ECP NSH+E C TC+ C
Sbjct: 942 RLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEECI-TCTETC 1000
Query: 1550 SALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLID-NCRQQ 1608
L+ P C D C+EGCQCD G+ G CV +CGC G +T +D +C+
Sbjct: 1001 ETLTLGPICVDSCSEGCQCDEGYALLGSQCVTRSECGCNFEGHQLATNETFWVDLDCQIF 1060
Query: 1609 CTCHAGKGMV-CQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLP 1667
C C V C+ CK + C GG+ C +
Sbjct: 1061 CYCSGTDNRVHCETIPCKDDEYCMEEGGLYYCQART------------------------ 1096
Query: 1668 NYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNP 1727
+A+C + G HY +FDG FDFQ +C +L TTG S+ F VT KN++R
Sbjct: 1097 --DASCIVSGYGHYLTFDGFPFDFQTSCPLILCTTG-SRPSSDSFPKFVVTAKNEDRDPS 1153
Query: 1728 AVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVA 1787
+V+ V V G +I IH+ K V VN LP+ + G+I++ ++
Sbjct: 1154 LALWVKQVDVTVFGYSIVIHR--AYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVET 1211
Query: 1788 DFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWR 1847
DFGL+V YDW + +T+P S + GLCG + NP++D P G LA S+ +G SW
Sbjct: 1212 DFGLKVVYDWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWV 1271
Query: 1848 APGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGC 1907
D C C CP+C ++E + L F+ CH+ V P F+K C
Sbjct: 1272 KR--DTFCQVGCGDRCPSCA--KVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNC 1327
Query: 1908 VLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPA 1967
+ D C+ GG C L +Y + CQ G+ + WR C +TCP NSHYE C C
Sbjct: 1328 LFDSCIDGGAVQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQP 1387
Query: 1968 SCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWAD 2027
C A + + C CVEGC CDAG+VL+ C+ L + CGC+++G Y+E FW +
Sbjct: 1388 RC---AAIRLKSDCSHYCVEGCHCDAGYVLNGKSCI-LPHSCGCYSDGKYYEPKQLFW-N 1442
Query: 2028 GTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDG 2087
C++ CRC + C P C E C L +G GC T+ C A G + T DG
Sbjct: 1443 SDCTRRCRCF-RRNVIQCDPRQCKSDEECA-LRNGVRGCFSTKTSYCLAAGGGVFRTFDG 1500
Query: 2088 HRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSA 2147
F C ++LS C P +F + + + + ++ V I + ++
Sbjct: 1501 AFLRFPANCAFVLSTICQKLP--DISFQLIINFDKWSAPNLTIISPVYFYINEEQILIND 1558
Query: 2148 RWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAA 2207
R ++V+G V +PF + S +V+ T+ + + ++G + +++ +
Sbjct: 1559 R--NTVKVNGTQVNVPFITGLATKIYSSEGFLVIDTSPDIQIYYNGFNVIKISISERLQN 1616
Query: 2208 SLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQ------GCGECVSKPCPSP 2253
+CGLCGN+N D DD + GKP W+ G Q C E +
Sbjct: 1617 KVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKTNGMQKRPLAPSCNELQFSQYAAM 1676
Query: 2254 CTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVA 2313
C + G C ++ G PC+GL+ P +++ C LD C LC ++A
Sbjct: 1677 CDNVHIQKMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYLDGC-YSHKKFQLCGSLA 1735
Query: 2314 TYVAACQAAGAQLGEWRRPDFC 2335
Y AC++ G EW + C
Sbjct: 1736 AYGEACRSFGILSTEWIEKENC 1757
Score = 778 bits (2010), Expect = 0.0
Identities = 471/1560 (30%), Positives = 715/1560 (45%), Gaps = 93/1560 (5%)
Query: 1190 GCVHQGTYHPPGQTFYPGPGCDSLCHCQE-GGLVSCESSSCGPHEACQPSGGSLGCVAVG 1248
GC +G + G+ F+ C C C + + C+ +SC P+E C+P G C AV
Sbjct: 259 GCTSRGQFLRRGEVFWDDLNCTVKCRCLDFNNEIYCQEASCSPYEVCEPKGKFFYCSAVE 318
Query: 1249 SSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVT 1308
+STC G+PHY TFDG F F G+C Y+LA+ C L F+V +N VS
Sbjct: 319 TSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHRRGSAVSWV 378
Query: 1309 RVITVQVANFTLRLEQRQW-KVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVA 1367
+ ++V+V + + + + + +V VN + LPV L G ++ Q G +ETDFGL V
Sbjct: 379 KELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQSGISTAVETDFGLLVT 438
Query: 1368 YDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSP 1427
+D +Y ++VPG+Y CGLCGNYN +P DDF +P+G A + + G SW D
Sbjct: 439 FDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHADWK 498
Query: 1428 CLPPTPCPPGSEDCIPS-HKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKD 1486
C C+ + +C E Y ++CG L+ GPL C +VDP +
Sbjct: 499 C---------DSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHS 549
Query: 1487 CIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFC--PMECPPNSHYELCADT 1544
C++DLC N ++LC I AY CQA G + WRT+T C ++CP SHY +C +
Sbjct: 550 CVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSS 609
Query: 1545 CSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYE-PEQTVLID 1603
C CS L+A C C EGC+C+ GF+ + CVP+ +CGC +G YY E
Sbjct: 610 CPDTCSDLTASRNCATPCTEGCECNQGFVLSTSQCVPLHKCGCDFDGHYYTMGEFFWATA 669
Query: 1604 NCRQQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQG 1663
NC QC C G + C +C G+VC E G QG
Sbjct: 670 NCTVQCLCEEGGDVYCFNKTCGSGEVC-------------------------AVEDGYQG 704
Query: 1664 VCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQN 1723
C P E C L + H+FDG + F +Y L T CP + N+
Sbjct: 705 -CFPKRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKT-CP-----ERPEYLEIDINKK 757
Query: 1724 RGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKA 1783
+ + +++R + + + I IG V +NG LP G++ + + +
Sbjct: 758 KPDAGPAWLRGLRILVADQEVKI--GGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNST 815
Query: 1784 LLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWG 1843
+ + + V Y + + L ++Y GLCG + N +++ PNG ++ ++
Sbjct: 816 TVESKGVVTVQYSDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFL 875
Query: 1844 GSWRAPGWDPLCWDECRGSCPTCPEDR--LEQYEGPGFCGPLASGTGGPFTTCHAHVPPE 1901
SW ++ +C EC C D L+ Y CG + + F CH V
Sbjct: 876 ESWTT--FEEICNGECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVT 933
Query: 1902 SFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVC 1961
++++ C+ +C GG+ LC ++A Y +AC+ A V + WR C + CPENSH+E C
Sbjct: 934 AYYRTCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEEC 993
Query: 1962 GPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAG 2021
C +C + LT +C C EGCQCD G+ L +CV + CGC G
Sbjct: 994 -ITCTETCET---LTLGPICVDSCSEGCQCDEGYALLGSQCV-TRSECGCNFEGHQLATN 1048
Query: 2022 SEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPH 2081
FW D C +C C + C C E C + G + CQ + A C G H
Sbjct: 1049 ETFWVDLDCQIFCYCSGTDNRVHCETIPCKDDEYC-MEEGGLYYCQARTDASCIVSGYGH 1107
Query: 2082 YVTLDGHRFDFQGTCEYLLSAPCHGPPLGA-ENFTVTVANEHRGSQAVSYTRSVTLQIYN 2140
Y+T DG FDFQ +C +L P + F VT NE R + + V + ++
Sbjct: 1108 YLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNEDRDPSLALWVKQVDVTVFG 1167
Query: 2141 HSLTLSARWPRKLQVDGVFVALPFQL-DSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRL 2199
+S+ + + + V+ + LP +L ++ G VVV T GL + +D +F+ +
Sbjct: 1168 YSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYDWKTFLSI 1227
Query: 2200 RVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQ-----------GCGECVSK 2248
VP + S GLCG YN +P DDL+ G A Q GCG+
Sbjct: 1228 TVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKRDTFCQVGCGD---- 1283
Query: 2249 PCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGL 2308
CPS E C +I + + CH V P +++ CL D+C G
Sbjct: 1284 RCPSCAKVEGFSKV--QQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGAVQTA 1341
Query: 2309 CPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEGCESA 2368
C + Y + CQ G + WR C + CP +SHYE C C C ++ C
Sbjct: 1342 CSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCAAIRLKSDCSHY 1401
Query: 2369 CREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQ 2428
C EGC CDAG+VL+G +C+ CGC DG+YY ++F+ +C RRC C + C
Sbjct: 1402 CVEGCHCDAGYVLNGKSCILPHSCGCYSDGKYYEPKQLFW-NSDCTRRCRCFRRNVIQC- 1459
Query: 2429 EGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHP 2488
+ C EEC L +GV+ C +T CLA GG + T DG +C++VL+ +C
Sbjct: 1460 DPRQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANCAFVLSTICQK 1519
Query: 2489 KPGDEDFSIVL--EKNAAGDL---QRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVG-R 2542
P D F +++ +K +A +L + + + + + V V+G V +P G
Sbjct: 1520 LP-DISFQLIINFDKWSAPNLTIISPVYFYINEEQILINDRNTVKVNGTQVNVPFITGLA 1578
Query: 2543 VRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNG 2602
++ + +V+ T+ +++ ++G + +SI + ++CGLCGNFNG+ +DD+V G
Sbjct: 1579 TKIYSSEGFLVIDTSPDIQIYYNGFNVIKISISERLQNKVCGLCGNFNGDLTDDYVTLRG 1638
Query: 2603 SAASSVETFGAAWRAPGSSK-----GCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQ 2657
S +W+ G K C E Q +C + + C +L + +
Sbjct: 1639 KPVVSSVVLAQSWKTNGMQKRPLAPSCNELQFSQYAAMCDNVHIQKMQGDGYCLKLTDMK 1698
Query: 2658 GPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFC 2717
G F C +L P ++ C D C K LC SLAAY AC++ G+ W C
Sbjct: 1699 GFFQPCYGLLDPLPFYESCYLDGC-YSHKKFQLCGSLAAYGEACRSFGILSTEWIEKENC 1757
Score = 725 bits (1872), Expect = 0.0
Identities = 432/1376 (31%), Positives = 668/1376 (48%), Gaps = 55/1376 (3%)
Query: 1645 CHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGC 1704
C +C P E C+ +G C +TC ++G+PHYH+FDG F FQG+C Y+LA C
Sbjct: 294 CQEASCSPYEVCEPKGKFFYCSAVETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQ-C 352
Query: 1705 PGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGVLTA 1764
+ T L F+V KN++R AVS+V+ ++V G I I K G+V+V N ++T+
Sbjct: 353 --LQTSSLPFFSVEAKNEHRRGSAVSWVKELSVEVNGYKILIPKGSYGRVKV--NDLVTS 408
Query: 1765 LPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNP 1824
LPV++ G + + Q + DFGL V++D +++P SY + CGLCGN ++NP
Sbjct: 409 LPVTLDLGTVKIYQSGISTAVETDFGLLVTFDGQHYASISVPGSYINSTCGLCGNYNKNP 468
Query: 1825 NNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLA 1884
+D + P+G A S+ G SWR D C C +C C Y G +CG L
Sbjct: 469 LDDFLRPDGRPAMSVLDLGESWRVYHADWKCDSGCVDNCTQCDAATEALYFGSDYCGFL- 527
Query: 1885 SGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRA 1944
+ T GP C V P +F CV D+C + +LC+A+ +Y CQA G+ I DWR
Sbjct: 528 NKTDGPLWECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRT 587
Query: 1945 QVGCEIT--CPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRC 2002
Q GC T CP SHY VC CP +C + LT C PC EGC+C+ GFVLS +C
Sbjct: 588 QTGCVSTVQCPSFSHYSVCTSSCPDTC---SDLTASRNCATPCTEGCECNQGFVLSTSQC 644
Query: 2003 VPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSG 2062
VPL+ CGC +G Y+ G FWA C+ C C GG + C +CG GEVC + G
Sbjct: 645 VPLHK-CGCDFDGHYYTMGEFFWATANCTVQCLCEEGG-DVYCFNKTCGSGEVCAV-EDG 701
Query: 2063 QHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEH 2122
GC P C + T DG + F Y L C P E + + N+
Sbjct: 702 YQGCFPKRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERP---EYLEIDI-NKK 757
Query: 2123 RGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDS-LLHAHLSGADVVV 2181
+ ++ R + + + + + + +++++G V LPF S L + + V
Sbjct: 758 KPDAGPAWLRGLRILVADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTV 817
Query: 2182 TTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA--------G 2233
+ +++ + + +R+ Y GLCG YN + +D+ GK
Sbjct: 818 ESKGVVTVQYSDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLES 877
Query: 2234 WQVGGAQGCGEC--VSKPCPSPCTPEQQESFGGPDACGVIS-ATDGPLAPCHGLVPPAQY 2290
W GEC + K C + E + + CG+I+ ++ CHG+V Y
Sbjct: 878 WTTFEEICNGECGDLLKACNNDS--ELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAY 935
Query: 2291 FQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGD 2350
++ CL CQ G+ LC +VA Y +AC+ A ++G WR DFCPL+CP +SH+E C
Sbjct: 936 YRTCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEEC-I 994
Query: 2351 SCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPG 2410
+C +C +L+ C +C EGC CD G+ L G CV +CGC +G E F+
Sbjct: 995 TCTETCETLTLGPICVDSCSEGCQCDEGYALLGSQCVTRSECGCNFEGHQLATNETFWVD 1054
Query: 2411 PECERRCEC-GPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDG 2469
+C+ C C G V C E C E C E G+ C A C+ +G HY+T DG
Sbjct: 1055 LDCQIFCYCSGTDNRVHC-ETIPCKDDEYCMEEGGLYYCQARTDASCIVSGYGHYLTFDG 1113
Query: 2470 RVYDLHGSCSYVLAQVCHPKPGDEDFS--IVLEKNAAGD------LQRLLVTVAGQ--VV 2519
+D SC +L +P + F +V KN D ++++ VTV G V+
Sbjct: 1114 FPFDFQTSCPLILCTT-GSRPSSDSFPKFVVTAKNEDRDPSLALWVKQVDVTVFGYSIVI 1172
Query: 2520 SLAQGQQVTVDGEAVALPVAVG--RVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSP 2577
A V V+ E + LP+ +G ++ + + G ++V++T GL++++D L +++P
Sbjct: 1173 HRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYDWKTFLSITVPRS 1232
Query: 2578 FRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCL 2637
+ GLCG +NGN DD +P G ASSV FG +W + C GCG + CP C
Sbjct: 1233 MQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKRDTF--CQVGCGDR-CPSCA 1289
Query: 2638 AEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAY 2697
E + + C + N F+ C + ++P+ +++ C++D C G C L Y
Sbjct: 1290 KVEGFS-KVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGAVQTACSWLQNY 1348
Query: 2698 TAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCEC 2757
+ CQ G+ V WR + C + CP +SHY C CQ CAA+ + C+ C EGC C
Sbjct: 1349 ASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCAAIRLKSDCSHYCVEGCHC 1408
Query: 2758 DDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGR 2817
D ++L+ CI CGC +G+Y SDC+ RC C + + C C
Sbjct: 1409 DAGYVLNGKSCILPHSCGCYSDGKYYEPKQLFWNSDCTRRCRCFRRNVIQCDPRQCKSDE 1468
Query: 2818 VCEVKAEARNCWATR-GLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYR 2876
C ++ R C++T+ C+ + G TFDGA + + LS+ C L + I +
Sbjct: 1469 ECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANCAFVLSTICQKLPD-ISFQL 1527
Query: 2877 VVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDG 2936
++ + + V+ + + + + V VNG +V++P + + + +G
Sbjct: 1528 IINFDKWSAPNLTIISPVYFYINEEQILINDRNTVKVNGTQVNVPFITGLATKI-YSSEG 1586
Query: 2937 SLLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHDSQEKPAM 2992
L++ +Q++ + + +S K+CG CGNF+GD T+D+ + KP +
Sbjct: 1587 FLVIDTSPDIQIYYNGFNVIKISISERLQNKVCGLCGNFNGDLTDDYVTLRGKPVV 1642
>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
Length = 5765
Score = 414 bits (1064), Expect = e-115
Identities = 376/1379 (27%), Positives = 549/1379 (39%), Gaps = 256/1379 (18%)
Query: 466 AESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRGSRRV 525
A + VC GD HY TFDG + G C+Y E C F+V+ + GSR V
Sbjct: 71 AHNGRVCSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCRA--AYEDFNVQLRRGLVGSRPV 128
Query: 526 SYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGL 585
V V ++A + + G V L++ QR LP S + L V QSG +++ L
Sbjct: 129 --VTRVVIKAQGLVLEASNGSV---LINGQREELPYSRTG--LLVEQSGD--YIKVSIRL 179
Query: 586 VVTYDWDCQ--LALSLPARFQDQVCGLCGNYNGDPA-DDFLTPDGALAPDAVEFASSWKL 642
V+T+ W+ + L L ++ +Q CGLCG++NG PA ++F + L P ++F + KL
Sbjct: 180 VLTFLWNGEDSALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLTP--LQFGNLQKL 237
Query: 643 DDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVY 702
D C D CT + + +C T L FA CH +D +L C
Sbjct: 238 DGPTEQCPDPLPLPAGNCT-------DEEGICHR-TLLGPAFAECHALVDSTAYLAACAQ 289
Query: 703 DLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSC 762
DLC C Y++ C G +WR P CP +CP N +++ CG C +C
Sbjct: 290 DLCRCP---TCPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTC 346
Query: 763 NGAAAPSNCSGRPCVEGCVCLPGFVA------SGGACVPASSCGCTFQGLQLAPGQEVWA 816
+ C CV+GC C PG + C+P C CT G +PG
Sbjct: 347 SNPQRAQLCEDH-CVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHGGRTYSPGTSF-- 403
Query: 817 DELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFD 876
+ C CTC+G Q C+D CP GTC G H ++D
Sbjct: 404 NTTCS-SCTCSGGLWQ--CQD-LPCP-------------------GTCSVQGGAHISTYD 440
Query: 877 GRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRG-SQTVSYTRAVRVEARGVKVAVR 935
+ +D G C+Y+L C + +F VL E G + + +AV + G A+R
Sbjct: 441 EKLYDLHGDCSYVLSKKCADS----SFTVLAELRKCGLTDNENCLKAVTLSLDGGDTAIR 496
Query: 936 REYPGQVLVDDVLQYLPFQAADGQVQVFRQGR-DAVVRTDFGLTVTYDW--NARVTAKVP 992
+ G V ++ + LP AA+ + +F VV+T GL + +V ++
Sbjct: 497 VQADGGVFLNSIYTQLPLSAAN--ITLFTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLD 554
Query: 993 SSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPKLD 1052
++ +CGLCGNFN + ADD G A AF N+W+ + C
Sbjct: 555 PAHQGQMCGLCGNFNQNQADDFTALSGVVEATGAAFANTWKAQA--ACANARNSFEDPCS 612
Query: 1053 SLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATY 1112
V + +++ C L DP F CHS ++P+ +C++D C LC AL++Y
Sbjct: 613 LSVENENYARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNCERSEDCLCAALSSY 672
Query: 1113 AAACQAAGATVHPWRSEELCP---LSCPPHSHYEACSYGCPLSC---GDLPVPGGCGSEC 1166
AC A G + WR + +C +CP Y C +C + V
Sbjct: 673 VHACAAKGVQLSDWR-DGVCTKYMQNCPKSQRYAYVVDACQPTCRGLSEADVTCSVSFVP 731
Query: 1167 HEGCVCDEG-FALSGESCLPLASCGCVHQGTYHPPGQTFY-------------------- 1205
+GC C G F +C+P C C GT PG+ +
Sbjct: 732 VDGCTCPAGTFLNDAGACVPAQECPCYAHGTVLAPGEVVHDEGAVCSCTGGKLSCLGASL 791
Query: 1206 ----------------------PGPGCDSLCHCQEGGLVSCESSSCGPHEACQP---SGG 1240
PG C CH + V C S+ C C P S G
Sbjct: 792 QKSTGCAAPMVYLDCSNSSAGTPGAECLRSCHTLD---VGCFSTHCVSGCVCPPGLVSDG 848
Query: 1241 SLGCVA--------------------VGSSTCQ------------------ASGDPHYTT 1262
S GC+A V +TC A GD H+ T
Sbjct: 849 SGGCIAEEDCPCVHNEATYKPGETIRVDCNTCTCRNRRWECSHRLCLGTCVAYGDGHFIT 908
Query: 1263 FDGRRFDFMGTCVYVLAQT-CGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLR 1321
FDG R+ F G+C Y+LAQ CG F ++ EN+ G + ++ I + V ++ L
Sbjct: 909 FDGDRYSFEGSCEYILAQDYCGDNTTHGTFRIVTENIPCGTTGTTCSKAIKLFVESYELI 968
Query: 1322 LEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGN 1381
L++ +K G P + G +VIET G+ V++D V + + +
Sbjct: 969 LQEGTFKAVARGPGGDPP-------YKIRYMGIFLVIET-HGMAVSWDRKTSVFIRLHQD 1020
Query: 1382 YYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDC 1441
Y ++CGLCGN++ + +DF + S G+A EFGNSW+ L P+ CP +
Sbjct: 1021 YKGRVCGLCGNFDDNAINDFATRSRSVVGDALEFGNSWK--------LSPS-CP---DAL 1068
Query: 1442 IPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCL--GGGNLS 1499
P C +K ++ C +L PT ++C VD + C+ D C GG+
Sbjct: 1069 APKDPCTANPFRKSWAQKQCSILHGPT--FAACRSQVDSTKYYEACVNDACACDSGGDCE 1126
Query: 1500 ILCSNIHAYVSACQAAGGHVEPWRTETFCPMECP---PNS----HYELCADTCSLGCSAL 1552
C+ + AY AC AG V WRT CP+ C P+ HY+ C C C
Sbjct: 1127 CFCTAVAAYAQACHDAGLCVS-WRTPDTCPLFCDFYNPHGGCEWHYQPCGAPCLKTCRNP 1185
Query: 1553 SAPPQC------QDGCAEGCQCDSGFLYNGQACVPIQQCGCY-HNGVYYEPEQTV-LIDN 1604
S C +GC C F +N + QCGCY +G YY+ V +N
Sbjct: 1186 SG--HCLVDLPGLEGCYPKCPPSQPF-FNEDQMKCVAQCGCYDKDGNYYDVGARVPTAEN 1242
Query: 1605 CRQQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGV 1664
C Q C C PSG + C H +
Sbjct: 1243 C-QSCN-------------------CTPSG--IQC-----AHSLE--------------A 1261
Query: 1665 CLPNYEATCWLWGDPHYHSFDGRKFDFQGTC----NYVLATTGCPGVSTQGLTPFTVTT 1719
C YE + + D Y++ DG C + CPG T TPFT TT
Sbjct: 1262 CTCTYEDRTYSYQDVIYNTTDGLGACLIAICGSNGTIIRKAVACPG--TPATTPFTFTT 1318
Score = 397 bits (1021), Expect = e-110
Identities = 346/1267 (27%), Positives = 510/1267 (40%), Gaps = 181/1267 (14%)
Query: 864 CQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAV 923
C GD HY +FDG F F G C Y+ C AA F V + GS+ V TR V
Sbjct: 77 CSTWGDFHYKTFDGDVFRFPGLCNYVFSEHC--RAAYEDFNVQLRRGLVGSRPV-VTRVV 133
Query: 924 RVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDW 983
++A+G+ + G VL++ + LP+ V+ Q D ++ L +T+ W
Sbjct: 134 -IKAQGLVLEASN---GSVLINGQREELPYSRTGLLVE---QSGD-YIKVSIRLVLTFLW 185
Query: 984 NARVTA--KVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCG 1041
N +A ++ YA CGLCG+FNG PA + L FGN + + G
Sbjct: 186 NGEDSALLELDPKYANQTCGLCGDFNGLPAFN-EFYAHNARLTPLQFGNLQKLD-----G 239
Query: 1042 ATEPGDCPKLDSLVAQQLQSKNECGILADPK-GP-FRECHSKLDPQGAVRDCVYDRCLLP 1099
TE CP D L +E GI GP F ECH+ +D + C D C P
Sbjct: 240 PTE--QCP--DPLPLPAGNCTDEEGICHRTLLGPAFAECHALVDSTAYLAACAQDLCRCP 295
Query: 1100 GQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPVP 1159
C Y+ C AG WR ELCP +CP + ++ C C +C +
Sbjct: 296 TCP---CATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSNPQRA 352
Query: 1160 GGCGSECHEGCVCDEGFA------LSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSL 1213
C C +GC C G + ++ CLPL C C H G + PG +F C S
Sbjct: 353 QLCEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHGGRTYSPGTSF--NTTCSS- 409
Query: 1214 CHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGT 1273
C C GGL C+ C TC G H +T+D + +D G
Sbjct: 410 CTCS-GGLWQCQDLPC-------------------PGTCSVQGGAHISTYDEKLYDLHGD 449
Query: 1274 CVYVLAQTCGTRPGLHRFAVLQENVAWG---NGRVSVTRVITVQVANFTLRLEQRQWKVT 1330
C YVL++ C F VL E G N +++ + +R+ Q V
Sbjct: 450 CSYVLSKKCADSS----FTVLAELRKCGLTDNENCLKAVTLSLDGGDTAIRV-QADGGVF 504
Query: 1331 VNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGN--YYQQMCG 1388
+N + +LP+ AN + + +V++T GL++ LV ++V V + + QMCG
Sbjct: 505 LNSIYTQLPLSAANITL-FTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLDPAHQGQMCG 563
Query: 1389 LCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCP 1448
LCGN+N + DDF +G F N+W+ + P C
Sbjct: 564 LCGNFNQNQADDFTALSGVVEATGAAFANTWKAQAACANARNSFEDP-----------CS 612
Query: 1449 PELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAY 1508
+E + +C L+ P S CH +++P+ +C+FD C + LC+ + +Y
Sbjct: 613 LSVENENYARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNCERSEDCLCAALSSY 672
Query: 1509 VSACQAAGGHVEPWRTE--TFCPMECPPNSHYELCADTCSLGCSALS-APPQCQDGCA-- 1563
V AC A G + WR T CP + Y D C C LS A C
Sbjct: 673 VHACAAKGVQLSDWRDGVCTKYMQNCPKSQRYAYVVDACQPTCRGLSEADVTCSVSFVPV 732
Query: 1564 EGCQCDSG-FLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGK------- 1615
+GC C +G FL + ACVP Q+C CY +G P + V + C+C GK
Sbjct: 733 DGCTCPAGTFLNDAGACVPAQECPCYAHGTVLAPGEVVHDEGA--VCSCTGGKLSCLGAS 790
Query: 1616 -----------------------------------GMVCQEHSCKPGQVCQP---SGGIL 1637
+ C C G VC P S G
Sbjct: 791 LQKSTGCAAPMVYLDCSNSSAGTPGAECLRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSG 850
Query: 1638 SCVTKDPCHGV----TCRPQETCKEQGGQGVCLPN-YEA-------TCWLWGDPHYHSFD 1685
C+ ++ C V T +P ET + C +E TC +GD H+ +FD
Sbjct: 851 GCIAEEDCPCVHNEATYKPGETIRVDCNTCTCRNRRWECSHRLCLGTCVAYGDGHFITFD 910
Query: 1686 GRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNIS 1745
G ++ F+G+C Y+LA C +T G F + T+N G + + + + +
Sbjct: 911 GDRYSFEGSCEYILAQDYCGDNTTHGT--FRIVTENIPCGTTGTTCSKAIKLFVESYELI 968
Query: 1746 IHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTL 1805
+ + G + G P + I L++ G+ VS+D V + L
Sbjct: 969 LQE---GTFKAVARGPGGDPPYKIRYMGIF--------LVIETHGMAVSWDRKTSVFIRL 1017
Query: 1806 PSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPT 1865
Y G VCGLCGN D N ND + ++ +G SW+ P C D P
Sbjct: 1018 HQDYKGRVCGLCGNFDDNAINDFATRSRSVVGDALEFGNSWKL---SPSCPDALAPKDP- 1073
Query: 1866 CPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDVCM--GGGDRDILCK 1923
C + + C L G F C + V +++ CV D C GGD + C
Sbjct: 1074 CTANPFRKSWAQKQCSIL---HGPTFAACRSQVDSTKYYEACVNDACACDSGGDCECFCT 1130
Query: 1924 ALASYVAACQAAGVVIEDWRAQVGCEITC----PENS---HYEVCGPPCPASCPSPAPLT 1976
A+A+Y AC AG+ + WR C + C P HY+ CG PC +C +P +
Sbjct: 1131 AVAAYAQACHDAGLCV-SWRTPDTCPLFCDFYNPHGGCEWHYQPCGAPCLKTCRNP---S 1186
Query: 1977 TPAVCEGPCVEGC--QCDAGFVLSADRCVPLNNGCGCW-ANGTYHEAGSEFWADGTCSQW 2033
+ + P +EGC +C + + CGC+ +G Y++ G+ C Q
Sbjct: 1187 GHCLVDLPGLEGCYPKCPPSQPFFNEDQMKCVAQCGCYDKDGNYYDVGARVPTAENC-QS 1245
Query: 2034 CRCGPGG 2040
C C P G
Sbjct: 1246 CNCTPSG 1252
Score = 353 bits (906), Expect = 1e-96
Identities = 341/1318 (25%), Positives = 489/1318 (37%), Gaps = 220/1318 (16%)
Query: 1673 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYV 1732
C WGD HY +FDG F F G CNYV + F V + G+ V V
Sbjct: 77 CSTWGDFHYKTFDGDVFRFPGLCNYVFSEH-----CRAAYEDFNVQLRRGLVGSRPV--V 129
Query: 1733 RVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVADFGLQ 1792
V + A G + E V +NG LP S R + S + L
Sbjct: 130 TRVVIKAQGLVL-----EASNGSVLINGQREELPYS----RTGLLVEQSGDYIKVSIRLV 180
Query: 1793 VSYDWNWRVD--VTLPSSYHGAVCGLCGNMDRNPNNDQVFP-NGTLAPSIPIWGGSWRAP 1849
+++ WN + L Y CGLCG+ + P ++ + N L P +G +
Sbjct: 181 LTFLWNGEDSALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLTPLQ--FGNLQKLD 238
Query: 1850 GWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVL 1909
G C D C ++ G C G F CHA V ++ C
Sbjct: 239 GPTEQCPDPLPLPAGNCTDEE-------GICHRTLLGPA--FAECHALVDSTAYLAACAQ 289
Query: 1910 DVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASC 1969
D+C C Y C AG +WR C TCP N ++ CG PC +C
Sbjct: 290 DLCRCP---TCPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTC 346
Query: 1970 PSPAPLTTPAVCEGPCVEGCQCDAGFV------LSADRCVPLNNGCGCWANGTYHEAGSE 2023
+P +CE CV+GC C G ++ C+PL C C G + G+
Sbjct: 347 SNP---QRAQLCEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQ-CPCTHGGRTYSPGTS 402
Query: 2024 FWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYV 2083
F + TCS C C GG C C C G H
Sbjct: 403 F--NTTCSS-CTC--SGGLWQCQDLPC--------------------PGTCSVQGGAHIS 437
Query: 2084 TLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTLQIYNHS 2142
T D +D G C Y+LS C +FTV G + + ++VTL +
Sbjct: 438 TYDEKLYDLHGDCSYVLSKKC-----ADSSFTVLAELRKCGLTDNENCLKAVTLSLDGGD 492
Query: 2143 LTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVR--LR 2200
+ + + ++ ++ LP ++ S +VV T GL L ++ +R
Sbjct: 493 TAIRVQADGGVFLNSIYTQLPLSAANITLFTPSSFFIVVQTGLGLQLLVQLVPLMQVFVR 552
Query: 2201 VPAAYAASLCGLCGNYNQDPADDLKAVGG-----KPAGWQVGGAQGCGECVSKPCPSPCT 2255
+ A+ +CGLCGN+NQ+ ADD A+ G A AQ PC+
Sbjct: 553 LDPAHQGQMCGLCGNFNQNQADDFTALSGVVEATGAAFANTWKAQAACANARNSFEDPCS 612
Query: 2256 PEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATY 2315
+ C ++ + + CH ++ P + C+ D C + LC A+++Y
Sbjct: 613 LSVENENYARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNCERSEDCLCAALSSY 672
Query: 2316 VAACQAAGAQLGEWRRPDFCP---LQCPAHSHYELCGDSCPVSCPSLSAPEGCESAC--- 2369
V AC A G QL +W R C CP Y D+C +C LS + S
Sbjct: 673 VHACAAKGVQLSDW-RDGVCTKYMQNCPKSQRYAYVVDACQPTCRGLSEADVTCSVSFVP 731
Query: 2370 REGCVCDAG-FVLSGDTCVPVGQCGCLHDGRYYPLGEVFY-------------------- 2408
+GC C AG F+ CVP +C C G GEV +
Sbjct: 732 VDGCTCPAGTFLNDAGACVPAQECPCYAHGTVLAPGEVVHDEGAVCSCTGGKLSCLGASL 791
Query: 2409 ----------------------PGPECERRCE----------------CGPG------GH 2424
PG EC R C C PG G
Sbjct: 792 QKSTGCAAPMVYLDCSNSSAGTPGAECLRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGG 851
Query: 2425 VTCQEGAAC-------GPHEECRLEDGVQAC--------HATGCGRCLANGGIHYITLDG 2469
+E C P E R++ C H G C+A G H+IT DG
Sbjct: 852 CIAEEDCPCVHNEATYKPGETIRVDCNTCTCRNRRWECSHRLCLGTCVAYGDGHFITFDG 911
Query: 2470 RVYDLHGSCSYVLAQ-VCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVSLAQGQQVT 2528
Y GSC Y+LAQ C F IV E G T + + L
Sbjct: 912 DRYSFEGSCEYILAQDYCGDNTTHGTFRIVTENIPCGTTG----TTCSKAIKLFVESYEL 967
Query: 2529 VDGEAVALPVAVG-----RVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLC 2583
+ E VA G ++ G +V++ T G+ + +D + + + ++GR+C
Sbjct: 968 ILQEGTFKAVARGPGGDPPYKIRYMGIFLVIE-THGMAVSWDRKTSVFIRLHQDYKGRVC 1026
Query: 2584 GLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAP 2643
GLCGNF+ N +DF + S FG +W+ S C + P+ C A
Sbjct: 1027 GLCGNFDDNAINDFATRSRSVVGDALEFGNSWKL---SPSCPDALAPK--DPCTANPFRK 1081
Query: 2644 YESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCA--QKGDKAFLCRSLAAYTAAC 2701
+ + C L P FA C++ + ++Y+ CV D CA GD C ++AAY AC
Sbjct: 1082 SWAQKQCSILHGP--TFAACRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQAC 1139
Query: 2702 QAAGVAVKPWRTDSFCPLHCPAHS-------HYSICTRTCQGSC--------AALSGLTG 2746
AG+ V WRT CPL C ++ HY C C +C L GL G
Sbjct: 1140 HDAGLCVS-WRTPDTCPLFCDFYNPHGGCEWHYQPCGAPCLKTCRNPSGHCLVDLPGLEG 1198
Query: 2747 CTTRCFEGCECDDRFLLSQGVCIPVQDCGC-THNGRYLPVNSSLLTSDCSERCSCSSSSG 2805
C +C F Q C V CGC +G Y V + + T++ + C+C + SG
Sbjct: 1199 CYPKC---PPSQPFFNEDQMKC--VAQCGCYDKDGNYYDVGARVPTAENCQSCNC-TPSG 1252
Query: 2806 LTC----QAAGCP-PGRVCEVKAEARNCWATRGLCVLSV-GANLTTFDGARGATTSPG 2857
+ C +A C R + N G C++++ G+N T R A PG
Sbjct: 1253 IQCAHSLEACTCTYEDRTYSYQDVIYNTTDGLGACLIAICGSNGTII---RKAVACPG 1307
Score = 345 bits (886), Expect = 3e-94
Identities = 370/1407 (26%), Positives = 524/1407 (37%), Gaps = 291/1407 (20%)
Query: 1208 PGCDSLCHCQEGGLVSCESS---SCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFD 1264
P ++ H +GG + + S P PS L A C GD HY TFD
Sbjct: 31 PSWENAGHTMDGGAPTSSPTRRVSFVPPVTVFPSLSPLN-PAHNGRVCSTWGDFHYKTFD 89
Query: 1265 GRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVIT-VQVANFTLRLE 1323
G F F G C YV ++ C R A NV G V V+T V + L LE
Sbjct: 90 GDVFRFPGLCNYVFSEHC-------RAAYEDFNVQLRRGLVGSRPVVTRVVIKAQGLVLE 142
Query: 1324 QRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYY 1383
V +NG +LP + + Q G + + L ++ + + Y
Sbjct: 143 ASNGSVLINGQREELPY--SRTGLLVEQSGDYIKVSIRLVLTFLWNGEDSALLELDPKYA 200
Query: 1384 QQMCGLCGNYNGDPKDDFQKPNGSQAGNAN----EFGNSWEEVVPDSPCLPPTPCPPGSE 1439
Q CGLCG++NG P N A NA +FGN + P C P P P G+
Sbjct: 201 NQTCGLCGDFNGLPAF-----NEFYAHNARLTPLQFGNLQKLDGPTEQCPDPLPLPAGN- 254
Query: 1440 DCIPSHKCPPELEKKYQKEEFCGLLSSPTGP-LSSCHKLVDPQGPLKDCIFDLCLGGGNL 1498
C E E C + GP + CH LVD L C DLC
Sbjct: 255 -------CTDE-------EGICH--RTLLGPAFAECHALVDSTAYLAACAQDLCRCP--- 295
Query: 1499 SILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQC 1558
+ C+ Y C AGG WR CP CP N ++ C C+ CS C
Sbjct: 296 TCPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSNPQRAQLC 355
Query: 1559 QDGCAEGCQCDSG--------FLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCT 1610
+D C +GC C G ++G C+P+ QC C H G Y P + + CT
Sbjct: 356 EDHCVDGCFCPPGRSCTVLDDITHSG--CLPLGQCPCTHGGRTYSPGTS--FNTTCSSCT 411
Query: 1611 CHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYE 1670
C SGG+ C PC G TC QGG
Sbjct: 412 C---------------------SGGLWQCQDL-PCPG-------TCSVQGGA-------- 434
Query: 1671 ATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRG-NPAV 1729
H ++D + +D G C+YVL+ C S FTV + + G
Sbjct: 435 ---------HISTYDEKLYDLHGDCSYVLSKK-CADSS------FTVLAELRKCGLTDNE 478
Query: 1730 SYVRVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALLV-AD 1788
+ ++ VT++ G + +I G V +N + T LP+S A+ I++ +S ++V
Sbjct: 479 NCLKAVTLSLDGGDTAIRVQADGGV--FLNSIYTQLPLSAAN--ITLFTPSSFFIVVQTG 534
Query: 1789 FGLQVSYDWN--WRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSW 1846
GLQ+ +V V L ++ G +CGLCGN ++N +D +G + + + +W
Sbjct: 535 LGLQLLVQLVPLMQVFVRLDPAHQGQMCGLCGNFNQNQADDFTALSGVVEATGAAFANTW 594
Query: 1847 RAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKG 1906
+A + C E+ E Y +C L F+ CH+ + P+ F
Sbjct: 595 KAQAACANARNSFEDPCSLSVEN--ENY-ARHWCSRLTDPNSA-FSRCHSIINPKPFHSN 650
Query: 1907 CVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEI--TCPENSHYEVCGPP 1964
C+ D C D LC AL+SYV AC A GV + DWR V + CP++ Y
Sbjct: 651 CMFDTCNCERSEDCLCAALSSYVHACAAKGVQLSDWRDGVCTKYMQNCPKSQRYAYVVDA 710
Query: 1965 CPASCPSPAPLTTPAVCEGPCVEGCQCDAG-FVLSADRCVPLNNGCGCWANGTYHEAGSE 2023
C +C + V+GC C AG F+ A CVP C C+A+GT G
Sbjct: 711 CQPTCRGLSEADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQE-CPCYAHGTVLAPGEV 769
Query: 2024 FWADGTCSQWCRCGPGGGSLVCTPAS---------------------------------- 2049
+G C GG L C AS
Sbjct: 770 VHDEGAV-----CSCTGGKLSCLGASLQKSTGCAAPMVYLDCSNSSAGTPGAECLRSCHT 824
Query: 2050 ---------CGLGEVC--GLLPSGQHGCQPVSTAEC------------------------ 2074
C G VC GL+ G GC C
Sbjct: 825 LDVGCFSTHCVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKPGETIRVDCNTCTCRN 884
Query: 2075 QAWGDPHYVTL--------------DGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVAN 2120
+ W H + L DG R+ F+G+CEY+L+ G F + N
Sbjct: 885 RRWECSHRLCLGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNTTHGTFRIVTEN 944
Query: 2121 EHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVAL--------PFQLDSLLHA 2172
G+ + ++++ L + ++ L L +G F A+ P+++ +
Sbjct: 945 IPCGTTGTTCSKAIKLFVESYELILQ---------EGTFKAVARGPGGDPPYKIRYM--- 992
Query: 2173 HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA 2232
+V T G+++++D + V +R+ Y +CGLCGN++ + +D
Sbjct: 993 ----GIFLVIETHGMAVSWDRKTSVFIRLHQDYKGRVCGLCGNFDDNAINDFATRSRS-- 1046
Query: 2233 GWQVGGAQGCGEC--VSKPCP------SPCTPEQQESFGGPDACGVISATDGP-LAPCHG 2283
VG A G +S CP PCT C ++ GP A C
Sbjct: 1047 --VVGDALEFGNSWKLSPSCPDALAPKDPCTANPFRKSWAQKQCSIL---HGPTFAACRS 1101
Query: 2284 LVPPAQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPA 2341
V +Y++ C+ DAC G C AVA Y AC AG + WR PD CPL C
Sbjct: 1102 QVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACHDAGLCV-SWRTPDTCPLFCDF 1160
Query: 2342 HS-------HYELCGDSCPVSC--PS------LSAPEGCESACREGCVCDAGFVLSGDTC 2386
++ HY+ CG C +C PS L EGC C + + D
Sbjct: 1161 YNPHGGCEWHYQPCGAPCLKTCRNPSGHCLVDLPGLEGCYPKCP-----PSQPFFNEDQM 1215
Query: 2387 VPVGQCGCL-HDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECR----- 2440
V QCGC DG YY +G C+ C C P G AC E R
Sbjct: 1216 KCVAQCGCYDKDGNYYDVGARVPTAENCQ-SCNCTPSGIQCAHSLEACTCTYEDRTYSYQ 1274
Query: 2441 -----LEDGVQACHATGCGRCLANGGI 2462
DG+ AC CG +NG I
Sbjct: 1275 DVIYNTTDGLGACLIAICG---SNGTI 1298
Score = 306 bits (785), Expect = 2e-82
Identities = 283/1040 (27%), Positives = 398/1040 (38%), Gaps = 206/1040 (19%)
Query: 2074 CQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRS 2133
C WGD HY T DG F F G C Y+ S C E+F V + GS+ V TR
Sbjct: 77 CSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCRA---AYEDFNVQLRRGLVGSRPV-VTRV 132
Query: 2134 VTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDG 2193
V I L L A L ++G LP+ LL SG + V+ L+ ++G
Sbjct: 133 V---IKAQGLVLEASNGSVL-INGQREELPYSRTGLL-VEQSGDYIKVSIRLVLTFLWNG 187
Query: 2194 DSFVRLRVPAAYAASLCGLCGNYNQDPA-DDLKAVGGKPAGWQVGGAQ---GCGECVSKP 2249
+ L + YA CGLCG++N PA ++ A + Q G Q G E P
Sbjct: 188 EDSALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLTPLQFGNLQKLDGPTEQCPDP 247
Query: 2250 CPSP---CTPEQQESFGGPDACGVISATD-GP-LAPCHGLVPPAQYFQGCLLDACQVQGH 2304
P P CT E+ G+ T GP A CH LV Y C D C+
Sbjct: 248 LPLPAGNCTDEE----------GICHRTLLGPAFAECHALVDSTAYLAACAQDLCRCPTC 297
Query: 2305 PGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEG 2364
P C Y C AG Q WR P+ CP CP + ++ CG C +C + +
Sbjct: 298 P---CATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSNPQRAQL 354
Query: 2365 CESACREGCVCDAG---FVLSGDT---CVPVGQCGCLHDGRYYPLGEVFYPGPECERRCE 2418
CE C +GC C G VL T C+P+GQC C H GR Y G F
Sbjct: 355 CEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHGGRTYSPGTSF----------- 403
Query: 2419 CGPGGHVTCQEGAACGPHEECRLEDGVQACHATGC-GRCLANGGIHYITLDGRVYDLHGS 2477
+ TC C G+ C C G C GG H T D ++YDLHG
Sbjct: 404 -----NTTCSS---------CTCSGGLWQCQDLPCPGTCSVQGGAHISTYDEKLYDLHGD 449
Query: 2478 CSYVLAQVCHPKPGDEDFSIVLEKNAAG--DLQRLLVTVAGQVVSLAQGQQVTVDGEA-- 2533
CSYVL++ C D F+++ E G D + L V + +V DG
Sbjct: 450 CSYVLSKKC----ADSSFTVLAELRKCGLTDNENCLKAVTLSLDGGDTAIRVQADGGVFL 505
Query: 2534 ----VALPVAVGRVRV-TAEGRNMVLQTTKGLRLLFD--GDAHLLMSIPSPFRGRLCGLC 2586
LP++ + + T +V+QT GL+LL + + + +G++CGLC
Sbjct: 506 NSIYTQLPLSAANITLFTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLDPAHQGQMCGLC 565
Query: 2587 GNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYES 2646
GNFN N +DDF +G ++ F W+A + C P L+ E Y +
Sbjct: 566 GNFNQNQADDFTALSGVVEATGAAFANTWKAQAA---CANARNSFEDPCSLSVENENY-A 621
Query: 2647 NEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGV 2706
C +L +P F+ C ++++P + C++D C + + LC +L++Y AC A GV
Sbjct: 622 RHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNCERSEDCLCAALSSYVHACAAKGV 681
Query: 2707 AVKPWRTDSFCPLH---CPAHSHYSICTRTCQGSCAALSGLTGCTTRC------FEGCEC 2757
+ WR D C + CP Y+ CQ +C GL+ C +GC C
Sbjct: 682 QLSDWR-DGVCTKYMQNCPKSQRYAYVVDACQPTCR---GLSEADVTCSVSFVPVDGCTC 737
Query: 2758 D-DRFLLSQGVCIPVQD----------------------CGCTHNGRYLPVNSSLLTS-- 2792
FL G C+P Q+ C CT G+ + +SL S
Sbjct: 738 PAGTFLNDAGACVPAQECPCYAHGTVLAPGEVVHDEGAVCSCT-GGKLSCLGASLQKSTG 796
Query: 2793 --------DCSERCS--------------------------CSSSSGLTCQAAG------ 2812
DCS + C GL +G
Sbjct: 797 CAAPMVYLDCSNSSAGTPGAECLRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGCIAEE 856
Query: 2813 -CP---------PGRVCEVKAEARNCWATR---------GLCVLSVGANLTTFDGARGAT 2853
CP PG V C R G CV + TFDG R +
Sbjct: 857 DCPCVHNEATYKPGETIRVDCNTCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDRYSF 916
Query: 2854 TSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWV 2913
Y L+ G T +R+V E C G T +K + +
Sbjct: 917 EGSCEYILAQDYCGDNTTHGTFRIVTENIPC----------------GTTGTTCSKAIKL 960
Query: 2914 NGLRVDLPAEKLASVSVSRTPDGS----------LLVRQKAGVQVWLGANGKVAVIVSND 2963
+L ++ +V+R P G LV + G+ V V + + D
Sbjct: 961 FVESYELILQEGTFKAVARGPGGDPPYKIRYMGIFLVIETHGMAVSWDRKTSVFIRLHQD 1020
Query: 2964 HAGKLCGACGNFDGDQTNDW 2983
+ G++CG CGNFD + ND+
Sbjct: 1021 YKGRVCGLCGNFDDNAINDF 1040
Score = 251 bits (640), Expect = 1e-65
Identities = 246/946 (26%), Positives = 369/946 (39%), Gaps = 174/946 (18%)
Query: 455 CQVVGGKAGCV-AESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSV 513
C GG C C QG H +T+D + YD+ G CSY + + C++ +F+V
Sbjct: 410 CTCSGGLWQCQDLPCPGTCSVQGGAHISTYDEKLYDLHGDCSYVLSKKCADS----SFTV 465
Query: 514 EAKNEHRG-SRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQ 572
A+ G + + + VT+ ++ G V +++ ++LP+S + L
Sbjct: 466 LAELRKCGLTDNENCLKAVTLSLDGGDTAIRVQADGGVFLNSIYTQLPLSAANITLFT-P 524
Query: 573 SGPRAVVELVFGLVVTYDWD--CQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALA 630
S VV+ GL + Q+ + L Q Q+CGLCGN+N + ADDF G +
Sbjct: 525 SSFFIVVQTGLGLQLLVQLVPLMQVFVRLDPAHQGQMCGLCGNFNQNQADDFTALSGVVE 584
Query: 631 PDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQ--AQHYEGDRLCGMLTKLDGPFAVCH 688
FA++WK + ++ C + A+H+ C LT + F+ CH
Sbjct: 585 ATGAAFANTWKAQAACANARNSFEDPCSLSVENENYARHW-----CSRLTDPNSAFSRCH 639
Query: 689 DTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSP--ANCPLSCP 746
++P+PF C++D C LC LS+Y AC G+ + DWR +CP
Sbjct: 640 SIINPKPFHSNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLSDWRDGVCTKYMQNCP 699
Query: 747 ANSRYELCGPACPTSCNG-AAAPSNCS-GRPCVEGCVCLPG-FVASGGACVPASSCGCTF 803
+ RY AC +C G + A CS V+GC C G F+ GACVPA C C
Sbjct: 700 KSQRYAYVVDACQPTCRGLSEADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQECPCYA 759
Query: 804 QGLQLAPGQEVWADELCQRRCT-----CNGATHQ-----------VTCRDKQSCPAGERC 847
G LAPG EV DE CT C GA+ Q + C + + G C
Sbjct: 760 HGTVLAPG-EVVHDEGAVCSCTGGKLSCLGASLQKSTGCAAPMVYLDCSNSSAGTPGAEC 818
Query: 848 -------------------------SVQNGLLGCYPDRFGTCQGSG-----------DPH 871
V +G GC + C + D +
Sbjct: 819 LRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKPGETIRVDCN 878
Query: 872 YVSFDGRRFD-----FMGTCT--------------YLLVGS---------CGQNAALPAF 903
+ RR++ +GTC Y GS CG N F
Sbjct: 879 TCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNTTHGTF 938
Query: 904 RVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQA------AD 957
R++ EN G+ + ++A+++ ++ +LQ F+A D
Sbjct: 939 RIVTENIPCGTTGTTCSKAIKLFVESYEL--------------ILQEGTFKAVARGPGGD 984
Query: 958 GQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALR 1017
++ G V+ T G+ V++D V ++ Y +CGLCGNF+ + +D A R
Sbjct: 985 PPYKIRYMGIFLVIET-HGMAVSWDRKTSVFIRLHQDYKGRVCGLCGNFDDNAINDFATR 1043
Query: 1018 GGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQ---SKNECGILADPKGP 1074
+AL FGNSW + P C P D A + ++ +C IL P
Sbjct: 1044 SRSVVGDALEFGNSW--KLSPSC----PDALAPKDPCTANPFRKSWAQKQCSILHGP--T 1095
Query: 1075 FRECHSKLDPQGAVRDCVYDRCLLP--GQSGPLCDALATYAAACQAAGATVHPWRSEELC 1132
F C S++D CV D C G C A+A YA AC AG V WR+ + C
Sbjct: 1096 FAACRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACHDAGLCV-SWRTPDTC 1154
Query: 1133 PLSCP---PHS----HYEACSYGCPLSCGD------LPVPGGCGSECHEGCVCDEGFALS 1179
PL C PH HY+ C C +C + + +PG G C+ C + F +
Sbjct: 1155 PLFCDFYNPHGGCEWHYQPCGAPCLKTCRNPSGHCLVDLPGLEG--CYPKCPPSQPF-FN 1211
Query: 1180 GESCLPLASCGCVHQ-GTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPS 1238
+ +A CGC + G Y+ G C S C+C G+ S
Sbjct: 1212 EDQMKCVAQCGCYDKDGNYYDVGARVPTAENCQS-CNCTPSGIQCAHSLE---------- 1260
Query: 1239 GGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGT 1284
C + D Y T DG +G C+ + + GT
Sbjct: 1261 ----ACTCTYEDRTYSYQDVIYNTTDG-----LGACLIAICGSNGT 1297
Score = 120 bits (301), Expect = 2e-26
Identities = 126/497 (25%), Positives = 182/497 (36%), Gaps = 94/497 (18%)
Query: 1222 VSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQT 1281
VS S C H C+ C+ C G HY+TFDG + F G C YVL +
Sbjct: 5061 VSDPSQPCDFHYECE-------CI------CSMWGGSHYSTFDGTSYTFRGNCTYVLMRE 5107
Query: 1282 CGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVV 1341
R G + L + + + R R + +D+ L V
Sbjct: 5108 IHARFG-NLSLYLDNHYCTASATAAAARC-------------PRALSIHYKSMDIVLTVT 5153
Query: 1342 LANGQIRASQHGSDVVIETDF---GLRVAYDLVYYVRVTVP---------GNYYQQMC-- 1387
+ +G+ + + + F G+ V+ +RV +P G +Q
Sbjct: 5154 MVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMRVDIPALGVSVTFNGQVFQARLPY 5213
Query: 1388 --------GLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSP---CLPPTPCPP 1436
G CG + +DD + +G+ A + + +W +VPDS C PT PP
Sbjct: 5214 SLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTW--LVPDSRKDGCWAPTGTPP 5271
Query: 1437 GSEDCIPSHK------CPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFD 1490
+ P CPP+ C L+ S + CH LV P CI D
Sbjct: 5272 TASPAAPVSSTPTPTPCPPQ--------PLCDLMLSQV--FAECHNLVPPGPFFNACISD 5321
Query: 1491 LCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTET--FCPMECPPNSHYELCADTCSLG 1548
C G L + C ++ AY C+A G WR T C + CPP Y+ C
Sbjct: 5322 HCRG--RLEVPCQSLEAYAELCRARGV-CSDWRGATGGLCDLTCPPTKVYKPCGPIQPAT 5378
Query: 1549 CSALSAPPQCQDGCAEGCQC-DSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQ 1607
C++ + PQ +G AEGC C + L+N + +Q C C + + + NC Q
Sbjct: 5379 CNSRNQSPQL-EGMAEGCFCPEDQILFNAHMGICVQACPCVGPDGFPKFPGERWVSNC-Q 5436
Query: 1608 QCTCHAGKGMVCQEHSCKPGQVCQPSGGILSC-------VTK----DPCHGVTCRPQETC 1656
C C G V CKP C G C VT+ +PC T T
Sbjct: 5437 SCVCDEGSVSV----QCKP-LPCDAQGQPPPCNRPGFVTVTRPRAENPCCPETVCVCNTT 5491
Query: 1657 KEQGGQGVCLPNYEATC 1673
VC P E+ C
Sbjct: 5492 TCPQSLPVCPPGQESIC 5508
Score = 119 bits (299), Expect = 3e-26
Identities = 119/431 (27%), Positives = 165/431 (38%), Gaps = 43/431 (9%)
Query: 1670 EATCWLWGDPHYHSFDGRKFDFQGTCNYVL-----ATTGCPGVSTQGLTPFTVTTKNQNR 1724
E C +WG HY +FDG + F+G C YVL A G + T R
Sbjct: 5075 ECICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTASATAAAAR 5134
Query: 1725 GNPAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGR--ISVAQGASK 1782
A+S + ++ + T +H E G + + +PVS + + V+ +
Sbjct: 5135 CPRALS-IHYKSMDIVLTVTMVHGKEEGLI------LFDQIPVSSGFSKNGVLVSVLGTT 5187
Query: 1783 ALLVADFGLQVSYDWNWRV-DVTLPSS-YHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIP 1840
+ V L VS +N +V LP S +H G CG N +D + +GT A S
Sbjct: 5188 TMRVDIPALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCK 5247
Query: 1841 IWGGSWRAP-GWDPLCWDECRGSCPTC-PEDRLEQYEGPGFCGPLASGT---GGPFTTCH 1895
+W P CW G+ PT P + P C P F CH
Sbjct: 5248 DMAKTWLVPDSRKDGCWAPT-GTPPTASPAAPVSSTPTPTPCPPQPLCDLMLSQVFAECH 5306
Query: 1896 AHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVG--CEITCP 1953
VPP FF C+ D C G ++ C++L +Y C+A GV DWR G C++TCP
Sbjct: 5307 NLVPPGPFFNACISDHCRGR--LEVPCQSLEAYAELCRARGVC-SDWRGATGGLCDLTCP 5363
Query: 1954 ENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWA 2013
Y+ CGP PA+C S EG EGC C +L C C
Sbjct: 5364 PTKVYKPCGPIQPATCNS---RNQSPQLEG-MAEGCFCPEDQILFNAHMGICVQACPCVG 5419
Query: 2014 NGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGL----------GEVCGLLPSGQ 2063
+ + E W Q C C G S+ C P C G V P +
Sbjct: 5420 PDGFPKFPGERWVSN--CQSCVCDEGSVSVQCKPLPCDAQGQPPPCNRPGFVTVTRPRAE 5477
Query: 2064 HGCQPVSTAEC 2074
+ C P + C
Sbjct: 5478 NPCCPETVCVC 5488
Score = 115 bits (288), Expect = 7e-25
Identities = 113/405 (27%), Positives = 161/405 (39%), Gaps = 62/405 (15%)
Query: 467 ESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTM----------VELCSEDDTLPAFSVEAK 516
E +C G HY+TFDG Y G C+Y + + L ++ A + A
Sbjct: 5073 ECECICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTASATAAA 5132
Query: 517 NEHRGSRRVSYVGLVTVRAYSHSVSLTRG-EVGFVLVDNQRSRLPVS--LSEGRLRVYQS 573
+ + Y + V +V++ G E G +L D ++PVS S+ + V
Sbjct: 5133 ARCPRALSIHYKSMDIVL----TVTMVHGKEEGLILFD----QIPVSSGFSKNGVLVSVL 5184
Query: 574 GPRAV-VEL-VFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAP 631
G + V++ G+ VT++ A + F + G CG + DD L DG A
Sbjct: 5185 GTTTMRVDIPALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAA 5244
Query: 632 DAVEFASSWKLDDGDYLCEDGC---------------QNNCPACTPGQAQHYEGDRLCGM 676
+ A +W + D +DGC ++ P TP Q LC +
Sbjct: 5245 SCKDMAKTWLVPDSR---KDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQ-----PLCDL 5296
Query: 677 LTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWR 736
+ L FA CH+ + P PF C+ D C G C+ L AYA+ C G+ DWR
Sbjct: 5297 M--LSQVFAECHNLVPPGPFFNACISDHC--RGRLEVPCQSLEAYAELCRARGV-CSDWR 5351
Query: 737 SPAN--CPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPG---FVASGG 791
C L+CP Y+ CGP P +CN G EGC C F A G
Sbjct: 5352 GATGGLCDLTCPPTKVYKPCGPIQPATCNSRNQSPQLEG--MAEGCFCPEDQILFNAHMG 5409
Query: 792 ACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCR 836
CV A C G PG E W CQ C C+ + V C+
Sbjct: 5410 ICVQACPC-VGPDGFPKFPG-ERWVSN-CQ-SCVCDEGSVSVQCK 5450
Score = 110 bits (276), Expect = 2e-23
Identities = 135/554 (24%), Positives = 193/554 (34%), Gaps = 98/554 (17%)
Query: 2339 CPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCG----- 2393
C H + +CP S P +S+ + GC D +P+ Q
Sbjct: 4976 CNQHCDIDRFQGACPTSPPPVSSAPLSSPSPAPGC----------DNAIPLRQVNETWTL 5025
Query: 2394 -------CLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQ 2446
C+ D R L + P +VTC H ++ D Q
Sbjct: 5026 ENCTVARCVGDNRVVLL--------------DPKPVANVTC-----VNKHLPIKVSDPSQ 5066
Query: 2447 ACHATGCGRCLAN--GGIHYITLDGRVYDLHGSCSYVLAQVCHPKPG------DEDFSIV 2498
C C+ + GG HY T DG Y G+C+YVL + H + G D +
Sbjct: 5067 PCDFHYECECICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTA 5126
Query: 2499 LEKNAAGDLQRLLVTVAGQV-----VSLAQGQQ---VTVDGEAVALPVAVGRVRVTAEGR 2550
AA R L + V++ G++ + D V+ + V V+ G
Sbjct: 5127 SATAAAARCPRALSIHYKSMDIVLTVTMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGT 5186
Query: 2551 NMVLQTTK--GLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSV 2608
+ G+ + F+G S F G CG N DD + +G+ A+S
Sbjct: 5187 TTMRVDIPALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASC 5246
Query: 2609 ETFGAAWRAPGSSK-GCGEGCG-----PQGCPVCLAEETAPYESNEACGQLRNPQGPFAT 2662
+ W P S K GC G PV P C + + FA
Sbjct: 5247 KDMAKTWLVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQPLCDLMLSQ--VFAE 5304
Query: 2663 CQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWR--TDSFCPLH 2720
C ++ P +F C+ D C +G C+SL AY C+A GV WR T C L
Sbjct: 5305 CHNLVPPGPFFNACISDHC--RGRLEVPCQSLEAYAELCRARGVC-SDWRGATGGLCDLT 5361
Query: 2721 CPAHSHYSICTRTCQGSCAA------LSGLTGCTTRCFEGCEC-DDRFLLSQGVCIPVQD 2773
CP Y C +C + L G+ EGC C +D+ L + + I VQ
Sbjct: 5362 CPPTKVYKPCGPIQPATCNSRNQSPQLEGMA-------EGCFCPEDQILFNAHMGICVQA 5414
Query: 2774 CGCTHNGRYLPVNSSLLTSDCSERCSCSSSS------GLTCQAAGCP-----PGRVCEVK 2822
C C + S+C + C C S L C A G P PG V +
Sbjct: 5415 CPCVGPDGFPKFPGERWVSNC-QSCVCDEGSVSVQCKPLPCDAQGQPPPCNRPGFVTVTR 5473
Query: 2823 AEARNCWATRGLCV 2836
A N +CV
Sbjct: 5474 PRAENPCCPETVCV 5487
Score = 93.6 bits (231), Expect = 3e-18
Identities = 126/500 (25%), Positives = 176/500 (35%), Gaps = 84/500 (16%)
Query: 780 CVCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQ-RRCTCNGAT-------- 830
C P V+S P+ + GC + L E W E C RC +
Sbjct: 4989 CPTSPPPVSSAPLSSPSPAPGCD-NAIPLRQVNETWTLENCTVARCVGDNRVVLLDPKPV 5047
Query: 831 HQVTCRDK----------QSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRF 880
VTC +K Q C C C G HY +FDG +
Sbjct: 5048 ANVTCVNKHLPIKVSDPSQPCDFHYECEC-------------ICSMWGGSHYSTFDGTSY 5094
Query: 881 DFMGTCTYLLVGSCGQNAALPAFRVLVENEH-RGSQTVSYTRAVRVEARGVK-------- 931
F G CTY+L+ +A + ++N + S T + R R + K
Sbjct: 5095 TFRGNCTYVLMREI--HARFGNLSLYLDNHYCTASATAAAARCPRALSIHYKSMDIVLTV 5152
Query: 932 VAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYD---WNARVT 988
V + G +L D + F V V V G++VT++ + AR+
Sbjct: 5153 TMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMRVDIPALGVSVTFNGQVFQARLP 5212
Query: 989 AKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSW--QEETRPGCGATEPG 1046
+ + E CG C N + DD R G AA+ +W + + GC A P
Sbjct: 5213 YSLFHNNTEGQCGTCTN---NQRDDCLQRDGTTAASCKDMAKTWLVPDSRKDGCWA--PT 5267
Query: 1047 DCPKLDSLVAQQLQSKNECGILADP------KGPFRECHSKLDPQGAVRDCVYDRCLLPG 1100
P S A + P F ECH+ + P C+ D C G
Sbjct: 5268 GTPPTASPAAPVSSTPTPTPCPPQPLCDLMLSQVFAECHNLVPPGPFFNACISDHC--RG 5325
Query: 1101 QSGPLCDALATYAAACQAAGATVHPWRSEE--LCPLSCPPHSHYEACSYGCPLSC---GD 1155
+ C +L YA C+A G WR LC L+CPP Y+ C P +C
Sbjct: 5326 RLEVPCQSLEAYAELCRARG-VCSDWRGATGGLCDLTCPPTKVYKPCGPIQPATCNSRNQ 5384
Query: 1156 LPVPGGCGSECHEGCVCDEGFAL-SGESCLPLASCGCVHQGTYHPPGQTFYPG----PGC 1210
P G EGC C E L + + + +C CV P G +PG C
Sbjct: 5385 SPQLEGMA----EGCFCPEDQILFNAHMGICVQACPCV-----GPDGFPKFPGERWVSNC 5435
Query: 1211 DSLCHCQEGGL-VSCESSSC 1229
S C C EG + V C+ C
Sbjct: 5436 QS-CVCDEGSVSVQCKPLPC 5454
Score = 93.2 bits (230), Expect = 3e-18
Identities = 127/558 (22%), Positives = 203/558 (36%), Gaps = 109/558 (19%)
Query: 1922 CKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEV--CGPPCPASCP--SPAPLTT 1977
C+A + + G VI + + GC N H ++ CP S P S APL++
Sbjct: 4948 CRAFGQFFSP----GEVIYNKTDRAGCHFYAVCNQHCDIDRFQGACPTSPPPVSSAPLSS 5003
Query: 1978 PAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCG 2037
P+ G D +PL +E W C+ RC
Sbjct: 5004 PSPAPG---------------CDNAIPLRQV-------------NETWTLENCTV-ARCV 5034
Query: 2038 PGGGSLVCTP-----ASCGLGEVCGLLPSGQHGCQPVSTAEC--QAWGDPHYVTLDGHRF 2090
++ P +C + + C EC WG HY T DG +
Sbjct: 5035 GDNRVVLLDPKPVANVTCVNKHLPIKVSDPSQPCDFHYECECICSMWGGSHYSTFDGTSY 5094
Query: 2091 DFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYT----RSVTLQIYNHSLTLS 2146
F+G C Y+L H N ++ + N + + A + R++++ + + L+
Sbjct: 5095 TFRGNCTYVLMREIHA---RFGNLSLYLDNHYCTASATAAAARCPRALSIHYKSMDIVLT 5151
Query: 2147 -----ARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTS-GLSLAFDGDSFVRLR 2200
+ + D + V+ F + +L + L + V + G+S+ F+G F + R
Sbjct: 5152 VTMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMRVDIPALGVSVTFNGQVF-QAR 5210
Query: 2201 VP-AAYAASLCGLCGNYNQDPADDLKAVGGKPAG--------WQVGGAQ--GC------- 2242
+P + + + G CG + DD G A W V ++ GC
Sbjct: 5211 LPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTWLVPDSRKDGCWAPTGTP 5270
Query: 2243 ------GECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLL 2296
S P P+PC P+ C ++ + A CH LVPP +F C+
Sbjct: 5271 PTASPAAPVSSTPTPTPCPPQ--------PLCDLMLSQ--VFAECHNLVPPGPFFNACIS 5320
Query: 2297 DACQVQGHPGGLCPAVATYVAACQAAGAQLGEWR--RPDFCPLQCPAHSHYELCGDSCPV 2354
D C +G C ++ Y C+A G +WR C L CP Y+ CG P
Sbjct: 5321 DHC--RGRLEVPCQSLEAYAELCRARGV-CSDWRGATGGLCDLTCPPTKVYKPCGPIQPA 5377
Query: 2355 SCPSLSAPEGCESACREGCVCDAGFVL-SGDTCVPVGQCGCLHDGRYYPLGEVFYPGPEC 2413
+C S + E EGC C +L + + V C C+ P G +PG
Sbjct: 5378 TCNSRNQSPQLEGMA-EGCFCPEDQILFNAHMGICVQACPCVG-----PDGFPKFPGERW 5431
Query: 2414 ERRCECGPGGHVTCQEGA 2431
C+ C EG+
Sbjct: 5432 VSNCQ-----SCVCDEGS 5444
Score = 39.3 bits (90), Expect = 0.059
Identities = 53/213 (24%), Positives = 72/213 (33%), Gaps = 53/213 (24%)
Query: 2202 PAAYAASLCGLCGNYNQDPA----DDLKAVGGKPAGWQVGGAQG--CGECVSKPCPSP-- 2253
P A +C QDP +D P G++ G CGECV C +P
Sbjct: 5540 PGALPCHMCTCLSGDTQDPTVQCQEDACNNTTCPQGFEYKRVAGQCCGECVQTACLTPDG 5599
Query: 2254 ----------------CTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLD 2297
CT E+ GG A+ ++ C G + C D
Sbjct: 5600 QPVQLNETWVNSHVDNCTVYLCEAEGGVHLLTPQPASCPDVSSCRGSLRKTGCCYSCEED 5659
Query: 2298 ACQVQ------GHPG-----------GLCPAVATYVAACQAAGAQLG--EWRR--PDFCP 2336
+CQV+ H G G CP + Y A QA Q + RR + P
Sbjct: 5660 SCQVRINTTILWHQGCETEVNITFCEGSCPGASKYSAEAQAMQHQCTCCQERRVHEETVP 5719
Query: 2337 LQCP-------AHSHYELCGDSCPVSCPSLSAP 2362
L CP ++H + CG P P+ AP
Sbjct: 5720 LHCPNGSAILHTYTHVDECG-CTPFCVPAPMAP 5751
>gi|169202626 PREDICTED: similar to mucin 5, partial [Homo sapiens]
Length = 2013
Score = 412 bits (1058), Expect = e-114
Identities = 364/1368 (26%), Positives = 549/1368 (40%), Gaps = 224/1368 (16%)
Query: 461 KAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHR 520
+A A + VC G HY TFDG + G C+Y E C F+++ +
Sbjct: 70 RASNPAHNGRVCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGA--AYEDFNIQLRRSQE 127
Query: 521 GSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVE 580
+ + V ++ + LT+G V LV+ LP S+ + + QS VE
Sbjct: 128 SAAPT--LSRVLMKVDGVVIQLTKGSV---LVNGHPVLLP--FSQSGVLIQQSSSYTKVE 180
Query: 581 LVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPA-DDFLTPDGALAPDAVEFASS 639
GLV+ ++ D L L L ++ ++ CGLCG++NG P + L+ + L P +EF +
Sbjct: 181 ARLGLVLMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTP--MEFGNL 238
Query: 640 WKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQ 699
K+DD C+D C+ G E L G L F+ C +D +LE
Sbjct: 239 QKMDDPTEQCQDPVPEPPRNCSTGFGICEE--LLHGQL------FSGCVALVDVGSYLEA 290
Query: 700 CVYDLCVVGGERL--SLCRGLSAYAQACLELGISVGDWRSPANCPLSCPANSRYELCGPA 757
C DLC L +C L+ Y++ C G DWR P CP CP N +Y C
Sbjct: 291 CRQDLCFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSP 350
Query: 758 CPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASG---GACVPASSCGCTFQGLQLAPGQEV 814
C +C+ C CV GC C G V CVP S C C + G APG
Sbjct: 351 CADTCSNQEHSRACEDH-CVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATY 409
Query: 815 WADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVS 874
D C CTC+G + +C++ CP GTC G H+ +
Sbjct: 410 STD--C-TNCTCSGG--RWSCQE-VPCP-------------------GTCSVLGGAHFST 444
Query: 875 FDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRG-SQTVSYTRAVRVEARGVKVA 933
FDG+++ G C+Y+L C + AF VL E G + + + ++V + GV+
Sbjct: 445 FDGKQYTVHGDCSYVLTKPCDSS----AFTVLAELRRCGLTDSETCLKSVTLSLDGVQTV 500
Query: 934 VRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVV-RTDFGLTVTYDW--NARVTAK 990
V + G+V ++ + LP AA+ V +FR ++ +T GL + ++ +
Sbjct: 501 VVIKASGEVFLNQIYTQLPISAAN--VTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQ 558
Query: 991 VPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPK 1050
+ CGLCGNFN ADD G A A AF N++ +T+ C
Sbjct: 559 LAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTF--KTQAACPNIRNSFEDP 616
Query: 1051 LDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALA 1110
V + +++ C L D GPF CH+ + P +C++D C LC AL+
Sbjct: 617 CSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNCERSEDCLCAALS 676
Query: 1111 TYAAACQAAGATVHPWRS------EELCPLSCPPHSHYEACSYGC-PLSCGDLPVPGGCG 1163
+Y AC A G + WR CP S H H C C LS GD+ G
Sbjct: 677 SYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVSTCQPTCRSLSEGDITC--SVG 734
Query: 1164 SECHEGCVCDEGFALSGE-SCLPLASCGCVHQGTYHPPGQTFY----------------- 1205
+GC+C +G L C+ ++C C H+G+ P G++ +
Sbjct: 735 FIPVDGCICPKGTFLDDTGKCVQASNCPCYHRGSMIPNGESVHDSGAICTCTHGKLSCIG 794
Query: 1206 ------------------------PGPGCDSLCHC-----------------------QE 1218
G GC CH E
Sbjct: 795 GQAPAPVCAAPMVFFDCRNATPGDTGAGCQKSCHTLDMTCYSPQCVPGCVCPDGLVADGE 854
Query: 1219 GGLVSCESSSCGPHEACQPSGGSL--GCVAVGS-------------STCQASGDPHYTTF 1263
GG ++ E C +EA +G ++ GC +TC GD HY TF
Sbjct: 855 GGCITAEDCPCVHNEASYRAGQTIRVGCNTCTCDSRMWRCTDDPCLATCAVYGDGHYLTF 914
Query: 1264 DGRRFDFMGTCVYVLAQT-CGTRPGLH-RFAVLQENVAWGNGRVSVTRVITVQVANFTLR 1321
DG+ + F G C Y L Q CG + F V+ ENV G + ++ I + + F L+
Sbjct: 915 DGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTTGTTCSKAIKIFLGGFELK 974
Query: 1322 LEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGN 1381
L + +V ++P + Q G +V++TD GL + +D + + +
Sbjct: 975 LSHGKVEVIGTDESQEVPYTI-------RQMGIYLVVDTDIGLVLLWDKKTSIFINLSPE 1027
Query: 1382 YYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDC 1441
+ ++CGLCGN++ +DF + S G+ EFGNSW+ L P+ CP +
Sbjct: 1028 FKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWK--------LSPS-CP---DAL 1075
Query: 1442 IPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCL--GGGNLS 1499
P C +K ++ C +L PT ++CH V+P + C+ D C GG+
Sbjct: 1076 APKDPCTANPFRKSWAQKQCSILHGPT--FAACHAHVEPARYYEACVNDACACDSGGDCE 1133
Query: 1500 ILCSNIHAYVSACQAAGGHVEPWRTETFCPMECP---PNSHYELCADTCSLGCSALSAPP 1556
C+ + AY AC G V WRT + CP+ C P E C + C P
Sbjct: 1134 CFCTAVAAYAQACHEVGLCVS-WRTPSICPLFCDYYNPEGQCEWHYQPCGVPCLRTCRNP 1192
Query: 1557 QCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKG 1616
+ C D ++ + C P +C P + + D + QC
Sbjct: 1193 R------GDCLRD---VWGLEGCYP--KC----------PPEAPIFDEDKMQCVATCPTP 1231
Query: 1617 MV---CQEH--SCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEA 1671
+ C H S +PG V SC+ + GV C T K + C+ Y
Sbjct: 1232 PLPPRCHVHGKSYRPGAVVPSDKNCQSCLCTE--RGVEC----TYKAE----ACVCTYNG 1281
Query: 1672 TCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTT 1719
+ GD YH+ DG G C + A G G + + P + TT
Sbjct: 1282 QRFHPGDVIYHTTDG-----TGGC--ISARCGANGTIERRVYPCSPTT 1322
Score = 362 bits (928), Expect = 4e-99
Identities = 324/1194 (27%), Positives = 473/1194 (39%), Gaps = 167/1194 (13%)
Query: 864 CQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRV-LVENEHRGSQTVSYTRA 922
C G HY +FDG F F G C Y+ CG AA F + L ++ + T+S
Sbjct: 81 CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCG--AAYEDFNIQLRRSQESAAPTLS---R 135
Query: 923 VRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYD 982
V ++ GV + + + G VLV+ LPF + +Q + V GL + ++
Sbjct: 136 VLMKVDGVVIQLTK---GSVLVNGHPVLLPFSQSGVLIQ--QSSSYTKVEARLGLVLMWN 190
Query: 983 WNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGA 1042
+ + ++ + YA CGLCG+FNG P L + FGN Q+ P
Sbjct: 191 HDDSLLLELDTKYANKTCGLCGDFNGMPVVS-ELLSHNTKLTPMEFGNL-QKMDDPTEQC 248
Query: 1043 TEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQS 1102
+P P + + + G L F C + +D + C D C
Sbjct: 249 QDPVPEPPRNCSTGFGICEELLHGQL------FSGCVALVDVGSYLEACRQDLCFCEDTD 302
Query: 1103 --GPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPVPG 1160
+C LA Y+ C AG WR + CP CP + Y C C +C +
Sbjct: 303 LLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEHSR 362
Query: 1161 GCGSECHEGCVCDEGFALSG---ESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQ 1217
C C GC C EG L C+P++ C CV+ G + PG T+ C + C C
Sbjct: 363 ACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATY--STDCTN-CTCS 419
Query: 1218 EGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYV 1277
GG SC+ C TC G H++TFDG+++ G C YV
Sbjct: 420 -GGRWSCQEVPC-------------------PGTCSVLGGAHFSTFDGKQYTVHGDCSYV 459
Query: 1278 LAQTCGTRPGLHRFAVLQENVAWG-NGRVSVTRVITVQVANF-TLRLEQRQWKVTVNGVD 1335
L + C + F VL E G + + +T+ + T+ + + +V +N +
Sbjct: 460 LTKPCDSSA----FTVLAELRRCGLTDSETCLKSVTLSLDGVQTVVVIKASGEVFLNQIY 515
Query: 1336 MKLPVVLANGQI-RASQHGSDVVIETDFGLRVAYDLVYYVRV--TVPGNYYQQMCGLCGN 1392
+LP+ AN I R S ++ +T GL++ LV +++ + Q CGLCGN
Sbjct: 516 TQLPISAANVTIFRPSTFF--IIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGN 573
Query: 1393 YNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELE 1452
+N DDF+ +G A F N+++ CP C +E
Sbjct: 574 FNSIQADDFRTLSGVVEATAAAFFNTFKT---------QAACPNIRNSF--EDPCSLSVE 622
Query: 1453 KKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSAC 1512
+ + +C L+ GP CH V P +C+FD C + LC+ + +YV AC
Sbjct: 623 NEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNCERSEDCLCAALSSYVHAC 682
Query: 1513 QAAGGHVEPWRTETFC--PME-CPPNSHYELCADTCSLGCSALSAPP-QCQDGC--AEGC 1566
A G + WR + C PM CP + Y TC C +LS C G +GC
Sbjct: 683 AAKGVQLGGWR-DGVCTKPMTTCPKSMTYHYHVSTCQPTCRSLSEGDITCSVGFIPVDGC 741
Query: 1567 QCDSG-FLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGK---------- 1615
C G FL + CV C CYH G ++V + CTC GK
Sbjct: 742 ICPKGTFLDDTGKCVQASNCPCYHRGSMIPNGESV--HDSGAICTCTHGKLSCIGGQAPA 799
Query: 1616 -------------------------------GMVCQEHSCKPGQVCQPSG----GILSCV 1640
M C C PG VC P G G C+
Sbjct: 800 PVCAAPMVFFDCRNATPGDTGAGCQKSCHTLDMTCYSPQCVPGCVC-PDGLVADGEGGCI 858
Query: 1641 TKDPCH----------GVTCRPQ-ETCKEQGGQGVCLPN-YEATCWLWGDPHYHSFDGRK 1688
T + C G T R TC C + ATC ++GD HY +FDG+
Sbjct: 859 TAEDCPCVHNEASYRAGQTIRVGCNTCTCDSRMWRCTDDPCLATCAVYGDGHYLTFDGQS 918
Query: 1689 FDFQGTCNYVLATTGCPGV-STQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIH 1747
+ F G C Y L C G STQ F V T+N G + + + + G + +
Sbjct: 919 YSFNGDCEYTLVQNHCGGKDSTQ--DSFRVVTENVPCGTTGTTCSKAIKIFLGGFELKLS 976
Query: 1748 KDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPS 1807
GKV V +P ++ I + ++ D GL + +D + + L
Sbjct: 977 H---GKVEVIGTDESQEVPYTIRQMGIYL-------VVDTDIGLVLLWDKKTSIFINLSP 1026
Query: 1808 SYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCP 1867
+ G VCGLCGN D ND + ++ + +G SW+ P C D P C
Sbjct: 1027 EFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWKL---SPSCPDALAPKDP-CT 1082
Query: 1868 EDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDVCM--GGGDRDILCKAL 1925
+ + C L G F CHAHV P +++ CV D C GGD + C A+
Sbjct: 1083 ANPFRKSWAQKQCSIL---HGPTFAACHAHVEPARYYEACVNDACACDSGGDCECFCTAV 1139
Query: 1926 ASYVAACQAAGVVIEDWRAQVGCEITC----PENS---HYEVCGPPCPASCPSP 1972
A+Y AC G+ + WR C + C PE HY+ CG PC +C +P
Sbjct: 1140 AAYAQACHEVGLCV-SWRTPSICPLFCDYYNPEGQCEWHYQPCGVPCLRTCRNP 1192
Score = 359 bits (922), Expect = 2e-98
Identities = 327/1209 (27%), Positives = 480/1209 (39%), Gaps = 209/1209 (17%)
Query: 1673 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYV 1732
C WG HY +FDG F F G CNYV + C G + + ++Q P +S V
Sbjct: 81 CSTWGSFHYKTFDGDVFRFPGLCNYVFSEH-C-GAAYEDFN--IQLRRSQESAAPTLSRV 136
Query: 1733 RVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVADFGLQ 1792
+ + ++ K V VNG LP S + + + Q +S + A GL
Sbjct: 137 LMKVDGVV--------IQLTKGSVLVNGHPVLLPFSQSG--VLIQQSSSYTKVEARLGLV 186
Query: 1793 VSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWD 1852
+ ++ + + + L + Y CGLCG+ + P ++ + T P+ G+ + D
Sbjct: 187 LMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLT--PMEFGNLQKMD-D 243
Query: 1853 PLCWDECRGSCPTCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDVC 1912
P ++C+ P P + G G C L G F+ C A V S+ + C D+C
Sbjct: 244 PT--EQCQDPVPEPPRNCST---GFGICEELLHGQ--LFSGCVALVDVGSYLEACRQDLC 296
Query: 1913 MGGGDRDIL---CKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASC 1969
D D+L C LA Y C AG + +DWR C CP N Y C PC +C
Sbjct: 297 FCE-DTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTC 355
Query: 1970 PSPAPLTTPAVCEGPCVEGCQCDAGFVLS---ADRCVPLNNGCGCWANGTYHEAGSEFWA 2026
+ CE CV GC C G VL CVP++ C C NG + G+ +
Sbjct: 356 SNQEH---SRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSK-CACVYNGAAYAPGATYST 411
Query: 2027 DGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVST-AECQAWGDPHYVTL 2085
D CT +C G+ CQ V C G H+ T
Sbjct: 412 D-----------------CTNCTCS---------GGRWSCQEVPCPGTCSVLGGAHFSTF 445
Query: 2086 DGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTLQIYNHSLT 2144
DG ++ G C Y+L+ PC + FTV G + + + +SVTL +
Sbjct: 446 DGKQYTVHGDCSYVLTKPCD-----SSAFTVLAELRRCGLTDSETCLKSVTLSLDGVQTV 500
Query: 2145 LSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAA 2204
+ + ++ ++ ++ LP ++ S ++ T+ GL L ++L + A
Sbjct: 501 VVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLA 560
Query: 2205 --YAASLCGLCGNYNQDPADDLKAVGG-----KPAGWQVGGAQGCGECVSKPCPSPCTPE 2257
CGLCGN+N ADD + + G A + Q + PC+
Sbjct: 561 PKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKTQAACPNIRNSFEDPCSLS 620
Query: 2258 QQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVA 2317
+ C ++ DGP CH V P Y+ C+ D C + LC A+++YV
Sbjct: 621 VENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNCERSEDCLCAALSSYVH 680
Query: 2318 ACQAAGAQLGEWRRPDFCP---LQCPAHSHYELCGDSCPVSCPSLSAPEGCESACR---- 2370
AC A G QLG WR C CP Y +C +C SLS EG + C
Sbjct: 681 ACAAKGVQLGGWR-DGVCTKPMTTCPKSMTYHYHVSTCQPTCRSLS--EG-DITCSVGFI 736
Query: 2371 --EGCVCDAGFVLSGDT--CVPVGQCGCLHDGRYYPLGE--------------------- 2405
+GC+C G L DT CV C C H G P GE
Sbjct: 737 PVDGCICPKGTFLD-DTGKCVQASNCPCYHRGSMIPNGESVHDSGAICTCTHGKLSCIGG 795
Query: 2406 -----------VFY------PG-------------------PECERRCEC-------GPG 2422
VF+ PG P+C C C G G
Sbjct: 796 QAPAPVCAAPMVFFDCRNATPGDTGAGCQKSCHTLDMTCYSPQCVPGCVCPDGLVADGEG 855
Query: 2423 GHVTCQEGAACGPHEE--------------CRLEDGVQACHATGC-GRCLANGGIHYITL 2467
G +T ++ C +E C + + C C C G HY+T
Sbjct: 856 GCITAED-CPCVHNEASYRAGQTIRVGCNTCTCDSRMWRCTDDPCLATCAVYGDGHYLTF 914
Query: 2468 DGRVYDLHGSCSYVLAQV-CHPKPGDED-FSIVLEKNAAGDL-----QRLLVTVAGQVVS 2520
DG+ Y +G C Y L Q C K +D F +V E G + + + + G +
Sbjct: 915 DGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTTGTTCSKAIKIFLGGFELK 974
Query: 2521 LAQGQ-QVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFR 2579
L+ G+ +V E+ +P + ++ G +V+ T GL LL+D + +++ F+
Sbjct: 975 LSHGKVEVIGTDESQEVPYTIRQM-----GIYLVVDTDIGLVLLWDKKTSIFINLSPEFK 1029
Query: 2580 GRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAE 2639
GR+CGLCGNF+ +DF + S V FG +W+ S C + P+ C A
Sbjct: 1030 GRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWKL---SPSCPDALAPK--DPCTAN 1084
Query: 2640 ETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCA--QKGDKAFLCRSLAAY 2697
+ + C L P FA C A + P+ Y+ CV D CA GD C ++AAY
Sbjct: 1085 PFRKSWAQKQCSILHGP--TFAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAAY 1142
Query: 2698 TAACQAAGVAVKPWRTDSFCPLHCPAHS-------HYS----ICTRTC---QGSCAA-LS 2742
AC G+ V WRT S CPL C ++ HY C RTC +G C +
Sbjct: 1143 AQACHEVGLCVS-WRTPSICPLFCDYYNPEGQCEWHYQPCGVPCLRTCRNPRGDCLRDVW 1201
Query: 2743 GLTGCTTRC 2751
GL GC +C
Sbjct: 1202 GLEGCYPKC 1210
Score = 343 bits (880), Expect = 1e-93
Identities = 350/1348 (25%), Positives = 526/1348 (39%), Gaps = 239/1348 (17%)
Query: 1252 CQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVI 1311
C G HY TFDG F F G C YV ++ CG + +Q + + +++RV+
Sbjct: 81 CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAA---YEDFNIQLRRSQESAAPTLSRVL 137
Query: 1312 TVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLV 1371
++V ++L + V VNG + LP + + Q S +E GL + ++
Sbjct: 138 -MKVDGVVIQLTKGS--VLVNGHPVLLP--FSQSGVLIQQSSSYTKVEARLGLVLMWNHD 192
Query: 1372 YYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPP 1431
+ + + Y + CGLCG++NG P + ++ EFGN + P C P
Sbjct: 193 DSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKL-TPMEFGNLQKMDDPTEQCQDP 251
Query: 1432 TPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDL 1491
P PP +C EL G L S C LVD L+ C DL
Sbjct: 252 VPEPP--RNCSTGFGICEEL--------LHGQL------FSGCVALVDVGSYLEACRQDL 295
Query: 1492 CLGGGN--LSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGC 1549
C LS +C + Y C AGG + WR FCP +CP N Y C C+ C
Sbjct: 296 CFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTC 355
Query: 1550 SALSAPPQCQDGCAEGCQCDSGFLYN--GQA-CVPIQQCGCYHNGVYYEPEQTVLIDNCR 1606
S C+D C GC C G + + GQ CVP+ +C C +NG Y P T D C
Sbjct: 356 SNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYSTD-CT 414
Query: 1607 QQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCL 1666
CTC G+ CQE C PG
Sbjct: 415 N-CTCSGGRWS-CQEVPC-PG--------------------------------------- 432
Query: 1667 PNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRG- 1725
TC + G H+ +FDG+++ G C+YVL T C + FTV + + G
Sbjct: 433 -----TCSVLGGAHFSTFDGKQYTVHGDCSYVL-TKPCDS------SAFTVLAELRRCGL 480
Query: 1726 NPAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALL 1785
+ + ++ VT++ G + G+ V +N + T LP+S A+ +++ + ++ ++
Sbjct: 481 TDSETCLKSVTLSLDGVQTVVVIKASGE--VFLNQIYTQLPISAAN--VTIFRPSTFFII 536
Query: 1786 V-ADFGLQVSYDW--NWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIW 1842
GLQ++ ++ + L G CGLCGN + +D +G + + +
Sbjct: 537 AQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAF 596
Query: 1843 GGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPES 1902
+++ P + C E+ E+Y +C L + GPF CHA V P +
Sbjct: 597 FNTFKTQAACPNIRNSFEDPCSLSVEN--EKY-AQHWCSQL-TDADGPFGRCHAAVKPGT 652
Query: 1903 FFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCE--ITCPENSHYEV 1960
++ C+ D C D LC AL+SYV AC A GV + WR V + TCP++ Y
Sbjct: 653 YYSNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHY 712
Query: 1961 CGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAG-FVLSADRCVPLNNGCGCWANGTYHE 2019
C +C S + V+GC C G F+ +CV +N C C+ G+
Sbjct: 713 HVSTCQPTCRSLSEGDITCSVGFIPVDGCICPKGTFLDDTGKCVQASN-CPCYHRGSMIP 771
Query: 2020 AGSEFWADG---TCSQW----------------------CRCGPGGGS------------ 2042
G G TC+ CR G +
Sbjct: 772 NGESVHDSGAICTCTHGKLSCIGGQAPAPVCAAPMVFFDCRNATPGDTGAGCQKSCHTLD 831
Query: 2043 LVCTPASCGLGEVC--GLLPSGQHGC---------------------------------- 2066
+ C C G VC GL+ G+ GC
Sbjct: 832 MTCYSPQCVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRVGCNTCTCDSRM 891
Query: 2067 ----QPVSTAECQAWGDPHYVTLDGHRFDFQGTCEY-LLSAPCHGPPLGAENFTVTVANE 2121
A C +GD HY+T DG + F G CEY L+ C G ++F V N
Sbjct: 892 WRCTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENV 951
Query: 2122 HRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVA--LPFQLDSLLHAHLSGADV 2179
G+ + ++++ + + L LS K++V G + +P+ + + G +
Sbjct: 952 PCGTTGTTCSKAIKIFLGGFELKLS---HGKVEVIGTDESQEVPYTIRQM------GIYL 1002
Query: 2180 VVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAG------ 2233
VV T GL L +D + + + + + +CGLCGN++ +D G
Sbjct: 1003 VVDTDIGLVLLWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFG 1062
Query: 2234 --WQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGP-LAPCHGLVPPAQY 2290
W++ + C + ++ PCT C ++ GP A CH V PA+Y
Sbjct: 1063 NSWKL--SPSCPDALAP--KDPCTANPFRKSWAQKQCSIL---HGPTFAACHAHVEPARY 1115
Query: 2291 FQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHS----- 2343
++ C+ DAC G C AVA Y AC G + WR P CPL C ++
Sbjct: 1116 YEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCV-SWRTPSICPLFCDYYNPEGQC 1174
Query: 2344 --HYELCGDSCPVSCPS--------LSAPEGCESAC-REGCVCDAGFVLSGDTC-VPVGQ 2391
HY+ CG C +C + + EGC C E + D + TC P
Sbjct: 1175 EWHYQPCGVPCLRTCRNPRGDCLRDVWGLEGCYPKCPPEAPIFDEDKMQCVATCPTPPLP 1234
Query: 2392 CGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAAC-GPHEECRLEDGVQACHA 2450
C G+ Y G V C+ C C G + AC + R G H
Sbjct: 1235 PRCHVHGKSYRPGAVVPSDKNCQ-SCLCTERGVECTYKAEACVCTYNGQRFHPGDVIYHT 1293
Query: 2451 T----GC--GRCLANGGIHYITLDGRVY 2472
T GC RC ANG T++ RVY
Sbjct: 1294 TDGTGGCISARCGANG-----TIERRVY 1316
Score = 288 bits (737), Expect = 6e-77
Identities = 268/1037 (25%), Positives = 389/1037 (37%), Gaps = 197/1037 (18%)
Query: 2074 CQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-----SQAV 2128
C WG HY T DG F F G C Y+ S C E+F + + S+ +
Sbjct: 81 CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGA---AYEDFNIQLRRSQESAAPTLSRVL 137
Query: 2129 SYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLS 2188
V +Q+ S+ V+G V LPF +L S + V GL
Sbjct: 138 MKVDGVVIQLTKGSVL----------VNGHPVLLPFSQSGVL-IQQSSSYTKVEARLGLV 186
Query: 2189 LAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPA-DDLKAVGGKPAGWQVGGAQGCGECVS 2247
L ++ D + L + YA CGLCG++N P +L + K + G Q + +
Sbjct: 187 LMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTPMEFGNLQKMDD-PT 245
Query: 2248 KPCPSPCTPEQQESFGGPDACGVISATDGPL-APCHGLVPPAQYFQGCLLDACQVQGHP- 2305
+ C P + G C + G L + C LV Y + C D C +
Sbjct: 246 EQCQDPVPEPPRNCSTGFGICEEL--LHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDL 303
Query: 2306 -GGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEG 2364
+C +A Y C AG +WR PDFCP +CP + Y C C +C +
Sbjct: 304 LSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEHSRA 363
Query: 2365 CESACREGCVCDAGFVLS--GDT-CVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGP 2421
CE C GC C G VL G T CVPV +C C+++G Y G + +C C C
Sbjct: 364 CEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATY--STDCTN-CTCS- 419
Query: 2422 GGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCSYV 2481
GG +CQE C G C GG H+ T DG+ Y +HG CSYV
Sbjct: 420 GGRWSCQE-VPCP-------------------GTCSVLGGAHFSTFDGKQYTVHGDCSYV 459
Query: 2482 LAQVCHPKPGDEDFSIVLEKNAAG--DLQRLLVTVA------GQVVSLAQGQQVTVDGEA 2533
L + C F+++ E G D + L +V VV + +V ++
Sbjct: 460 LTKPCDSSA----FTVLAELRRCGLTDSETCLKSVTLSLDGVQTVVVIKASGEVFLNQIY 515
Query: 2534 VALPVAVGRVRVTAEGRNMVL-QTTKGLRLLFD--GDAHLLMSIPSPFRGRLCGLCGNFN 2590
LP++ V + ++ QT+ GL+L L M + RG+ CGLCGNFN
Sbjct: 516 TQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFN 575
Query: 2591 GNWSDDFVLPNG----SAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYES 2646
+DDF +G +AA+ TF P + C L+ E Y +
Sbjct: 576 SIQADDFRTLSGVVEATAAAFFNTFKTQAACPNIRNSFEDPCS-------LSVENEKY-A 627
Query: 2647 NEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGV 2706
C QL + GPF C A + P Y+ C++D C + + LC +L++Y AC A GV
Sbjct: 628 QHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNCERSEDCLCAALSSYVHACAAKGV 687
Query: 2707 AVKPWRTDSFCP---LHCPAHSHYSICTRTCQGSCAALS-GLTGCTTRCF--EGCECDD- 2759
+ WR D C CP Y TCQ +C +LS G C+ +GC C
Sbjct: 688 QLGGWR-DGVCTKPMTTCPKSMTYHYHVSTCQPTCRSLSEGDITCSVGFIPVDGCICPKG 746
Query: 2760 RFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTS--------------------------- 2792
FL G C+ +C C H G +P S+ S
Sbjct: 747 TFLDDTGKCVQASNCPCYHRGSMIPNGESVHDSGAICTCTHGKLSCIGGQAPAPVCAAPM 806
Query: 2793 ---DCSERCSCSSSSG---------LTCQAAGCPPGRVCE-----------VKAEARNC- 2828
DC + +G +TC + C PG VC + AE C
Sbjct: 807 VFFDCRNATPGDTGAGCQKSCHTLDMTCYSPQCVPGCVCPDGLVADGEGGCITAEDCPCV 866
Query: 2829 -------------------------WATR-----GLCVLSVGANLTTFDGARGATTSPGV 2858
W C + + TFDG +
Sbjct: 867 HNEASYRAGQTIRVGCNTCTCDSRMWRCTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCE 926
Query: 2859 YEL-SSRCPGLQNTIPWYRVVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKGV--WVNG 2915
Y L + C G +T +RVV E C G T +K + ++ G
Sbjct: 927 YTLVQNHCGGKDSTQDSFRVVTENVPC----------------GTTGTTCSKAIKIFLGG 970
Query: 2916 LRVDLPAEKLASVSVSRTPDGSLLVRQKA---------GVQVWLGANGKVAVIVSNDHAG 2966
+ L K+ + + + +RQ G+ + + + +S + G
Sbjct: 971 FELKLSHGKVEVIGTDESQEVPYTIRQMGIYLVVDTDIGLVLLWDKKTSIFINLSPEFKG 1030
Query: 2967 KLCGACGNFDGDQTNDW 2983
++CG CGNFD ND+
Sbjct: 1031 RVCGLCGNFDDIAVNDF 1047
Score = 185 bits (469), Expect = 7e-46
Identities = 153/557 (27%), Positives = 248/557 (44%), Gaps = 61/557 (10%)
Query: 2445 VQACHATGCGR-CLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVL---E 2500
V+A + GR C G HY T DG V+ G C+YV ++ C EDF+I L +
Sbjct: 69 VRASNPAHNGRVCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGA--AYEDFNIQLRRSQ 126
Query: 2501 KNAAGDLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGL 2560
++AA L R+L+ V G V+ L +G V V+G V LP + V + ++ GL
Sbjct: 127 ESAAPTLSRVLMKVDGVVIQLTKGS-VLVNGHPVLLPFSQSGVLIQQSSSYTKVEARLGL 185
Query: 2561 RLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGS 2620
L+++ D LL+ + + + + CGLCG+FNG +L + + + +E FG +
Sbjct: 186 VLMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTPME-FGNLQKMDDP 244
Query: 2621 SKGCGEGC--GPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVY 2678
++ C + P+ C C +L + Q F+ C A++ Y C
Sbjct: 245 TEQCQDPVPEPPRNCSTGFG----------ICEELLHGQ-LFSGCVALVDVGSYLEACRQ 293
Query: 2679 DLCAQKGDK--AFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQG 2736
DLC + + +C +LA Y+ C AG + WR FCP CP + Y C C
Sbjct: 294 DLCFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCAD 353
Query: 2737 SCAALSGLTGCTTRCFEGCECDDRFLL---SQGVCIPVQDCGCTHNG-RYLPVNSSLLTS 2792
+C+ C C GC C + +L Q C+PV C C +NG Y P + ++
Sbjct: 354 TCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAP--GATYST 411
Query: 2793 DCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGA 2852
DC+ C+CS +CQ CP G C + GA+ +TFDG +
Sbjct: 412 DCT-NCTCSGGR-WSCQEVPCP------------------GTCSVLGGAHFSTFDGKQYT 451
Query: 2853 TTSPGVYELSSRCPGLQNTIPWYRVVAEVQICH-GKTEAVGQVHIFFQDGMVTLTPNKG- 2910
Y L+ C + V+AE++ C +E + DG+ T+ K
Sbjct: 452 VHGDCSYVLTKPCDSSA-----FTVLAELRRCGLTDSETCLKSVTLSLDGVQTVVVIKAS 506
Query: 2911 --VWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQ--VWLGANGKVAVIVSNDHAG 2966
V++N + LP A+V++ R ++ + G+Q + L ++ + ++ G
Sbjct: 507 GEVFLNQIYTQLPI-SAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRG 565
Query: 2967 KLCGACGNFDGDQTNDW 2983
+ CG CGNF+ Q +D+
Sbjct: 566 QTCGLCGNFNSIQADDF 582
Score = 151 bits (381), Expect = 1e-35
Identities = 128/453 (28%), Positives = 186/453 (41%), Gaps = 82/453 (18%)
Query: 419 GLAKAIGYATAADCGRTVLSPVEPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDP 478
G A A G + DC S SC+ + C C V+GG
Sbjct: 400 GAAYAPGATYSTDCTNCTCSGGRWSCQEVPCPG--TCSVLGGA----------------- 440
Query: 479 HYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRG---------SRRVSYVG 529
H++TFDG++Y + G CSY + + C AF+V A+ G S +S G
Sbjct: 441 HFSTFDGKQYTVHGDCSYVLTKPCDSS----AFTVLAELRRCGLTDSETCLKSVTLSLDG 496
Query: 530 LVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVV-------ELV 582
+ TV S G V ++ ++LP+S + + +++ ++ +L
Sbjct: 497 VQTVVVIKAS--------GEVFLNQIYTQLPISAAN--VTIFRPSTFFIIAQTSLGLQLN 546
Query: 583 FGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKL 642
LV T QL + L + + Q CGLCGN+N ADDF T G + A F +++K
Sbjct: 547 LQLVPTM----QLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKT 602
Query: 643 DDGDYLCEDGCQNNCPACTPGQ--AQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQC 700
+ ++ C + AQH+ C LT DGPF CH + P + C
Sbjct: 603 QAACPNIRNSFEDPCSLSVENEKYAQHW-----CSQLTDADGPFGRCHAAVKPGTYYSNC 657
Query: 701 VYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRS------PANCPLSCPANSRYELC 754
++D C LC LS+Y AC G+ +G WR CP S + C
Sbjct: 658 MFDTCNCERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVSTC 717
Query: 755 GPACPTSCNGAAAPSNCS-GRPCVEGCVCLPG-FVASGGACVPASSCGCTFQGLQLAPGQ 812
P C + G CS G V+GC+C G F+ G CV AS+C C +G + G+
Sbjct: 718 QPTCRSLSEG---DITCSVGFIPVDGCICPKGTFLDDTGKCVQASNCPCYHRGSMIPNGE 774
Query: 813 EVWADELCQRRCTCNGATHQVTCRDKQSCPAGE 845
V CTC TH K SC G+
Sbjct: 775 SVHDSGAI---CTC---TH-----GKLSCIGGQ 796
>gi|134031945 SCO-spondin [Homo sapiens]
Length = 5147
Score = 406 bits (1044), Expect = e-112
Identities = 390/1474 (26%), Positives = 546/1474 (37%), Gaps = 279/1474 (18%)
Query: 1131 LCPLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCV--CDEGFALSGESCL---- 1184
LCP+ PP + + C PG G+ C E EG + C
Sbjct: 73 LCPIYKPPETRPAKWNRTVRTCC-----PGWGGAHCTEALAKASPEGHCFAMWQCQLQAG 127
Query: 1185 -PLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLG 1243
AS G + + P GQ+++ G + C L SS QP G++G
Sbjct: 128 SANASAGSLEECCARPWGQSWWDGSS-QACRSCSSRHLPGSASSPA----LLQPLAGAVG 182
Query: 1244 CV----AVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLH---------- 1289
+ S+TC + HY TFDGR + F+G C Y+LA + +H
Sbjct: 183 QLWSQHQRPSATCASWSGFHYRTFDGRHYHFLGRCTYLLAGAADSTWAVHLTPGDRCPQP 242
Query: 1290 ----RFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANG 1345
R + E V G VSV + + ++ L QW
Sbjct: 243 GHCQRVTMGPEEVLIQAGNVSVKGQLVPEGQSWLLHGLSLQWL----------------- 285
Query: 1346 QIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPN 1405
G +V+ G+ V D + ++V + Q GLCG YNG P+DDF +P
Sbjct: 286 -------GDWLVLSGGLGVVVRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPG 338
Query: 1406 GSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKY---QKEEFCG 1462
G A A FGNSW +S CL G C P ++E + + ++ C
Sbjct: 339 GGLAMLAATFGNSWRLPGSESGCLDAVEVAQG---CDPLGLIDADVEPGHLRAEAQDVCH 395
Query: 1463 LLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGG-------GNLSILCSNIHAYVSACQAA 1515
L GP CH V P + C+F C G G +C+ +YV AC
Sbjct: 396 QLLE--GPFGQCHAQVSPAEYHEACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARR 453
Query: 1516 GGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQ--CQDGCAEGCQCDSGFL 1573
H+ WR FC CP Y C C C A+ + C++ C GC+C G
Sbjct: 454 HIHIR-WRKPGFCERLCPGGQLYSDCVSLCPPSCEAVGQGEEESCREECVSGCECPRGLF 512
Query: 1574 YNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEHSCKPGQVCQPS 1633
+NG CVP C CY+ Y P TV Q+C P
Sbjct: 513 WNGTLCVPAAHCPCYYCRQRYVPGDTVR--------------------------QLCNP- 545
Query: 1634 GGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQG 1693
CV +D + Q +C A C + GD HY +FDGR + F G
Sbjct: 546 -----CVCRDG------------RWHCAQALC----PAECAVGGDGHYLTFDGRSYSFWG 584
Query: 1694 TCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGK 1753
GC Q + ++ A S + ++V+ T+I +
Sbjct: 585 G-------QGCRYSLVQDYVKGQLLILLEHGACDAGSCLHAISVSLEDTHIQLRDSGA-- 635
Query: 1754 VRVCVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVD-VTLPSSYHGA 1812
V VNG LP A+G +SV + +S LL+ G QV + + V +TL +
Sbjct: 636 --VLVNGQDVGLPWIGAEG-LSVRRASSAFLLLRWPGAQVLWGLSDPVAYITLDPRHAHQ 692
Query: 1813 VCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPT------- 1865
V GLCG +N +D + P G + SI + ++ G +G CP+
Sbjct: 693 VQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAG---------KGRCPSEDSALLS 743
Query: 1866 -CPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKA 1924
C C L S F CH V E F+ C+ VC D LC
Sbjct: 744 PCTTHSQRHAFAEAACAILHSSV---FQECHRLVDKEPFYLRCLAAVCGCDPGSDCLCPV 800
Query: 1925 LASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGP 1984
L++Y C G WR Q C + CP Y C P C C P G
Sbjct: 801 LSAYARRCAQEGAS-PPWRNQTLCPVMCPGGQEYRECAPACGQHCGKPEDCGEL----GS 855
Query: 1985 CVEGCQCDAGFVLSAD-RCVPLN---------------------NGCGCWANGTY----- 2017
CV GC C G + + +CVP + N C C G +
Sbjct: 856 CVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRYAPGSATMKECNRCICQERGLWNCTAR 915
Query: 2018 HEAGSEF------WADGTCSQWC-------RCGPGG-GSLVCTPASCGLGEVC---GLLP 2060
H F +A G C C C G VC P + L E C L P
Sbjct: 916 HCPSQAFCPRELVYAPGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLLDERCVPPDLCP 975
Query: 2061 ---SGQ----------------------HGCQPVSTAECQAWGDPHYVTLDGHRFDFQGT 2095
SGQ H + CQA G PHYVT DG F + G
Sbjct: 976 CRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGA 1035
Query: 2096 CEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQV 2155
CEYLL G FTV+ N G+ ++ T+++ +++ + R + V
Sbjct: 1036 CEYLLVREASG------LFTVSAQNLPCGASGLTCTKALAVRL--EGTVVHMLRGRAVTV 1087
Query: 2156 DGVFVALP-FQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCG 2214
+GV V P L +G ++++T GL+L +DG + V +++ + + GLCG
Sbjct: 1088 NGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVAGLCG 1147
Query: 2215 NYNQDPADDLKAVGG--KPAGWQVGGAQGCGECVSKP--CPSPCTPEQQESFGGPDACGV 2270
+++ D ++DL++ G +P + +P P PCT + CG
Sbjct: 1148 DFDGDASNDLRSRQGVLEPTAELAAHSWRLSPLCPEPGDLPHPCTMNTHRAGWARARCGA 1207
Query: 2271 ISATDGPL-APCHGLVPPAQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLG 2327
+ PL CH VPP Q+++ CL DAC G LC A+ATY C G +
Sbjct: 1208 LLQ---PLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADECARHGHHV- 1263
Query: 2328 EWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEG--CE-SACREGCVCDAGFVLSGD 2384
WR + C LQC YE CG +CP +C G C+ AC EGC C G +L G
Sbjct: 1264 RWRSQELCSLQCEGGQVYEACGPTCPPTCHEQHPEPGWHCQVVACVEGCFCPEGTLLHGG 1323
Query: 2385 TCVPVGQCGCLHDGRYYPLGEVFY-----------------PGPECERRCECGPGGHVTC 2427
C+ C C +P G V G CE G C
Sbjct: 1324 ACLEPASCPCEWGRNSFPPGSVLQKDCGNCTCQEGQWHCGGDGGHCEELVPACAEGEALC 1383
Query: 2428 QEGAACGPH-------EECRLEDGVQACHATGCG 2454
QE C PH ++C + C A GCG
Sbjct: 1384 QENGHCVPHGWLCDNQDDCGDGSDEEGCAAPGCG 1417
Score = 389 bits (999), Expect = e-107
Identities = 363/1317 (27%), Positives = 514/1317 (39%), Gaps = 217/1317 (16%)
Query: 469 TAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRGSRRVSYV 528
+A C + HY TFDGR Y +G C+Y + + + + +RV+ +
Sbjct: 192 SATCASWSGFHYRTFDGRHYHFLGRCTYLLAGAADSTWAVHLTPGDRCPQPGHCQRVT-M 250
Query: 529 GLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVT 588
G V + +VS+ +G+ LV +S L LS L G V+ G+VV
Sbjct: 251 GPEEVLIQAGNVSV-KGQ----LVPEGQSWLLHGLSLQWL-----GDWLVLSGGLGVVVR 300
Query: 589 YDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYL 648
D +++S+ Q GLCG YNG P DDF+ P G LA A F +SW+L +
Sbjct: 301 LDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSESG 360
Query: 649 CEDGCQ--NNCPA-------CTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQ 699
C D + C PG + E +C L L+GPF CH + P + E
Sbjct: 361 CLDAVEVAQGCDPLGLIDADVEPGHLR-AEAQDVCHQL--LEGPFGQCHAQVSPAEYHEA 417
Query: 700 CVYDLCVVG-------GERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSCPANSRYE 752
C++ C G + ++C ++Y QAC I + WR P C CP Y
Sbjct: 418 CLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHI-RWRKPGFCERLCPGGQLYS 476
Query: 753 LCGPACPTSCN--GAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGCTFQGLQLAP 810
C CP SC G +C CV GC C G +G CVPA+ C C + + P
Sbjct: 477 DCVSLCPPSCEAVGQGEEESCR-EECVSGCECPRGLFWNGTLCVPAAHCPCYYCRQRYVP 535
Query: 811 GQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDP 870
G V R CN CRD + A C + C GD
Sbjct: 536 GDTV--------RQLCN----PCVCRDGRWHCAQALCPAE-------------CAVGGDG 570
Query: 871 HYVSFDGRRFDFMG--TCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAVRVEAR 928
HY++FDGR + F G C Y LV + ++L+ EH S A+ V
Sbjct: 571 HYLTFDGRSYSFWGGQGCRYSLVQDYVKG------QLLILLEHGACDAGSCLHAISVSLE 624
Query: 929 GVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVT 988
+ +R G VLV+ LP+ A+G + V R ++ G V + + V
Sbjct: 625 DTHIQLRDS--GAVLVNGQDVGLPWIGAEG-LSVRRASSAFLLLRWPGAQVLWGLSDPVA 681
Query: 989 -AKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGD 1047
+ +A + GLCG F + DD G + AF + +Q G
Sbjct: 682 YITLDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQ--------VAGKGR 733
Query: 1048 CPKLDSLVAQQLQSKNE--------CGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLP 1099
CP DS + + ++ C IL F+ECH +D + C+ C
Sbjct: 734 CPSEDSALLSPCTTHSQRHAFAEAACAIL--HSSVFQECHRLVDKEPFYLRCLAAVCGCD 791
Query: 1100 GQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPVP 1159
S LC L+ YA C GA+ PWR++ LCP+ CP Y C+ C CG P
Sbjct: 792 PGSDCLCPVLSAYARRCAQEGAS-PPWRNQTLCPVMCPGGQEYRECAPACGQHCGK---P 847
Query: 1160 GGCG--SECHEGCVCDEGFALSGE-SCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHC 1216
CG C GC C G E C+P + C C + PG C+ C C
Sbjct: 848 EDCGELGSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRYAPGSATM--KECNR-CIC 904
Query: 1217 QEGGLVSCESSSCGPHEACQ-----------------------PSGGSLGCVAVGSST-- 1251
QE GL +C + C C P+G + GCV +
Sbjct: 905 QERGLWNCTARHCPSQAFCPRELVYAPGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLL 964
Query: 1252 -----------CQASGD--------------------------------------PHYTT 1262
C+ SG PHY T
Sbjct: 965 DERCVPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVT 1024
Query: 1263 FDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRL 1322
FDG F + G C Y+L + GL F V +N+ G ++ T+ + V++ + +
Sbjct: 1025 FDGLAFTYPGACEYLLVREAS---GL--FTVSAQNLPCGASGLTCTKALAVRLEGTVVHM 1079
Query: 1323 EQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNY 1382
R VTVNGV + P V + + G +++ T GL + +D V V + +
Sbjct: 1080 -LRGRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQF 1138
Query: 1383 YQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCI 1442
++ GLCG+++GD +D + G A +SW L P PG +
Sbjct: 1139 RGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWR--------LSPLCPEPGD---L 1187
Query: 1443 PSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDL--CLGGGNLSI 1500
P H C + CG L P L CH V PQ + C++D C GG+
Sbjct: 1188 P-HPCTMNTHRAGWARARCGALLQPLFTL--CHAEVPPQQHYEWCLYDACGCDSGGDCEC 1244
Query: 1501 LCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPP--QC 1558
LCS I Y C G HV WR++ C ++C YE C TC C P C
Sbjct: 1245 LCSAIATYADECARHGHHVR-WRSQELCSLQCEGGQVYEACGPTCPPTCHEQHPEPGWHC 1303
Query: 1559 Q-DGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGK-- 1615
Q C EGC C G L +G AC+ C C G P +VL +C CTC G+
Sbjct: 1304 QVVACVEGCFCPEGTLLHGGACLEPASCPC-EWGRNSFPPGSVLQKDC-GNCTCQEGQWH 1361
Query: 1616 ----GMVCQE--HSCKPGQ-VCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVC 1665
G C+E +C G+ +CQ +G CV HG C Q+ C + + C
Sbjct: 1362 CGGDGGHCEELVPACAEGEALCQENG---HCVP----HGWLCDNQDDCGDGSDEEGC 1411
Score = 380 bits (975), Expect = e-104
Identities = 361/1276 (28%), Positives = 498/1276 (39%), Gaps = 173/1276 (13%)
Query: 863 TCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL---PAFRVLVENEHRGSQTVSY 919
TC HY +FDGR + F+G CTYLL G+ A+ P R + H T+
Sbjct: 194 TCASWSGFHYRTFDGRHYHFLGRCTYLLAGAADSTWAVHLTPGDRC-PQPGHCQRVTMG- 251
Query: 920 TRAVRVEARGVKVAVRREYPGQ--VLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGL 977
V ++A V V + GQ +L LQ+L G V+ G+
Sbjct: 252 PEEVLIQAGNVSVKGQLVPEGQSWLLHGLSLQWL--------------GDWLVLSGGLGV 297
Query: 978 TVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQ-EET 1036
V D ++ V GLCG +NG P DD GGG A A FGNSW+ +
Sbjct: 298 VVRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGS 357
Query: 1037 RPGC-GATEPGD-CPKLDSLVAQ------QLQSKNECGILADPKGPFRECHSKLDPQGAV 1088
GC A E C L + A + ++++ C L + GPF +CH+++ P
Sbjct: 358 ESGCLDAVEVAQGCDPLGLIDADVEPGHLRAEAQDVCHQLLE--GPFGQCHAQVSPAEYH 415
Query: 1089 RDCVYDRCL-------LPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSH 1141
C++ C G+ +C A+Y AC + WR C CP
Sbjct: 416 EACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHIR-WRKPGFCERLCPGGQL 474
Query: 1142 YEACSYGCPLSCGDLPV--PGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHP 1199
Y C CP SC + C EC GC C G +G C+P A C C + +
Sbjct: 475 YSDCVSLCPPSCEAVGQGEEESCREECVSGCECPRGLFWNGTLCVPAAHCPCYYCRQRYV 534
Query: 1200 PGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPH 1259
PG T C+ C C++G C + C + C GD H
Sbjct: 535 PGDTVRQL--CNP-CVCRDGRW-HCAQALC-------------------PAECAVGGDGH 571
Query: 1260 YTTFDGRRFDFMGT--CVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVAN 1317
Y TFDGR + F G C Y L Q + +L E+ A G S I+V + +
Sbjct: 572 YLTFDGRSYSFWGGQGCRYSLVQDYVKG----QLLILLEHGACDAG--SCLHAISVSLED 625
Query: 1318 FTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVR-V 1376
++L V VNG D+ LP + A G + + S ++ G +V + L V +
Sbjct: 626 THIQLRD-SGAVLVNGQDVGLPWIGAEG-LSVRRASSAFLLLRWPGAQVLWGLSDPVAYI 683
Query: 1377 TVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPP 1436
T+ + Q+ GLCG + + +DDF P G + F + ++ CP
Sbjct: 684 TLDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAGKGR-------CP- 735
Query: 1437 GSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGG 1496
SED C ++ E C +L S CH+LVD + C+ +C
Sbjct: 736 -SEDSALLSPCTTHSQRHAFAEAACAILHSSV--FQECHRLVDKEPFYLRCLAAVCGCDP 792
Query: 1497 NLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPP 1556
LC + AY C A G PWR +T CP+ CP Y CA C C P
Sbjct: 793 GSDCLCPVLSAYARRC-AQEGASPPWRNQTLCPVMCPGGQEYRECAPACGQHCGK---PE 848
Query: 1557 QCQD--GCAEGCQCDSGFLYNGQA-CVPIQQCGCYHNGVYYEPEQTVLIDN----CRQQ- 1608
C + C GC C G L++ + CVP C C Y P + + C+++
Sbjct: 849 DCGELGSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRYAPGSATMKECNRCICQERG 908
Query: 1609 ---CTC-HAGKGMVCQE-------------------HSCKPGQ----VCQPSGGILS--C 1639
CT H C HSC G VC P +L C
Sbjct: 909 LWNCTARHCPSQAFCPRELVYAPGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLLDERC 968
Query: 1640 VTKDPC----HGVTCRPQETCKEQGGQGVCLPNY--------EATCWLWGDPHYHSFDGR 1687
V D C G P T +E VC C G PHY +FDG
Sbjct: 969 VPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGL 1028
Query: 1688 KFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIH 1747
F + G C Y+L GL FTV+ +N G ++ + + V GT + +
Sbjct: 1029 AFTYPGACEYLLVR------EASGL--FTVSAQNLPCGASGLTCTKALAVRLEGTVVHML 1080
Query: 1748 KDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPS 1807
+ V VNGV P +S+ + LL GL + +D RV V L
Sbjct: 1081 RGRA----VTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSP 1136
Query: 1808 SYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCP-TC 1866
+ G V GLCG+ D + +ND G L P+ + SWR PLC + G P C
Sbjct: 1137 QFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRL---SPLCPEP--GDLPHPC 1191
Query: 1867 PEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDRDILCKA 1924
+ CG L FT CHA VPP+ ++ C+ D C GGD + LC A
Sbjct: 1192 TMNTHRAGWARARCGALLQPL---FTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSA 1248
Query: 1925 LASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGP 1984
+A+Y C G + WR+Q C + C YE CGP CP +C P
Sbjct: 1249 IATYADECARHGHHVR-WRSQELCSLQCEGGQVYEACGPTCPPTCHEQHPEPGWHCQVVA 1307
Query: 1985 CVEGCQCDAGFVLSADRCVPLNNGCGC-WANGTYHEAGSEFWAD-GTCS----QWCRCGP 2038
CVEGC C G +L C+ C C W ++ GS D G C+ QW CG
Sbjct: 1308 CVEGCFCPEGTLLHGGACLE-PASCPCEWGRNSF-PPGSVLQKDCGNCTCQEGQW-HCGG 1364
Query: 2039 GGGSLVCTPASCGLGE 2054
GG +C GE
Sbjct: 1365 DGGHCEELVPACAEGE 1380
Score = 300 bits (767), Expect = 2e-80
Identities = 270/901 (29%), Positives = 363/901 (40%), Gaps = 138/901 (15%)
Query: 455 CQVVGGKAGCV-AESTAVCRAQGDPHYTTFDGRRYDMMGT--CSYTMVELCSEDDTLPAF 511
C G+ C A A C GD HY TFDGR Y G C Y++V+ + L
Sbjct: 546 CVCRDGRWHCAQALCPAECAVGGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVKGQLLILL 605
Query: 512 SVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVY 571
EH S + ++V + L + G VLV+ Q LP +EG L V
Sbjct: 606 ------EHGACDAGSCLHAISVSLEDTHIQLR--DSGAVLVNGQDVGLPWIGAEG-LSVR 656
Query: 572 QSGPRAVVELVFGLVVTYDWDCQLA-LSLPARFQDQVCGLCGNYNGDPADDFLTPDGALA 630
++ ++ G V + +A ++L R QV GLCG + + DDFLTP G +
Sbjct: 657 RASSAFLLLRWPGAQVLWGLSDPVAYITLDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVE 716
Query: 631 PDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDT 690
FAS +++ G C CT +H + C +L F CH
Sbjct: 717 TSIAAFASKFQVA-GKGRCPSEDSALLSPCTTHSQRHAFAEAACAILHS--SVFQECHRL 773
Query: 691 LDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSCPANSR 750
+D PF +C+ +C LC LSAYA+ C + G S WR+ CP+ CP
Sbjct: 774 VDKEPFYLRCLAAVCGCDPGSDCLCPVLSAYARRCAQEGASP-PWRNQTLCPVMCPGGQE 832
Query: 751 YELCGPACPTSCNGAAAPSNCSGR-PCVEGCVCLPGFVASG-GACVPASSCGCTFQGLQL 808
Y C PAC C P +C CV GC C G + G CVP S C C +
Sbjct: 833 YRECAPACGQHCG---KPEDCGELGSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRY 889
Query: 809 APGQEVWADE---LCQRR----CTCNGATHQVTCRDK------------------QSCPA 843
APG + +CQ R CT Q C + SCPA
Sbjct: 890 APGSATMKECNRCICQERGLWNCTARHCPSQAFCPRELVYAPGACLLTCDSPSANHSCPA 949
Query: 844 G---------------ERC-------------------SVQNGLLGCY----------PD 859
G ERC ++Q C
Sbjct: 950 GSTDGCVCPPGTVLLDERCVPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQR 1009
Query: 860 RFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSY 919
R G CQ SG PHYV+FDG F + G C YLLV A F V +N G+ ++
Sbjct: 1010 RSGRCQASGAPHYVTFDGLAFTYPGACEYLLV-----REASGLFTVSAQNLPCGASGLTC 1064
Query: 920 TRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQ-VQVFRQGRDAVVRTDFGLT 978
T+A+ V G V + R G+ + + + P + G + + R G ++ T GLT
Sbjct: 1065 TKALAVRLEGTVVHMLR---GRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLT 1121
Query: 979 VTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRP 1038
+ +D RV ++ + + GLCG+F+GD ++DL R G A +SW+ P
Sbjct: 1122 LLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWR--LSP 1179
Query: 1039 GCGATEPGDCPKLDSLVAQQL-QSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCL 1097
C EPGD P ++ + ++ CG L P F CH+++ PQ C+YD C
Sbjct: 1180 LC--PEPGDLPHPCTMNTHRAGWARARCGALLQPL--FTLCHAEVPPQQHYEWCLYDACG 1235
Query: 1098 LP--GQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGD 1155
G LC A+ATYA C G V WRS+ELC L C YEAC CP +C +
Sbjct: 1236 CDSGGDCECLCSAIATYADECARHGHHVR-WRSQELCSLQCEGGQVYEACGPTCPPTCHE 1294
Query: 1156 L-PVPG-GCG-SECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFY------- 1205
P PG C C EGC C EG L G +CL ASC C PPG
Sbjct: 1295 QHPEPGWHCQVVACVEGCFCPEGTLLHGGACLEPASCPCEWGRNSFPPGSVLQKDCGNCT 1354
Query: 1206 ----------PGPGCDSLC-HCQEGGLVSCESSSCGPH-------EACQPSGGSLGCVAV 1247
G C+ L C EG + E+ C PH + C GC A
Sbjct: 1355 CQEGQWHCGGDGGHCEELVPACAEGEALCQENGHCVPHGWLCDNQDDCGDGSDEEGCAAP 1414
Query: 1248 G 1248
G
Sbjct: 1415 G 1415
Score = 244 bits (624), Expect = 7e-64
Identities = 296/1212 (24%), Positives = 426/1212 (35%), Gaps = 225/1212 (18%)
Query: 1941 DWRAQVGCEITCPENSHYEVCGPPCPASCPS-PAPLTTPAVCEG------PCVEGCQCDA 1993
D +++G + P + + P P CP P T PA P G C
Sbjct: 46 DHYSRLGWRLDLPWSGRSGLTRSPAPGLCPIYKPPETRPAKWNRTVRTCCPGWGGAHCTE 105
Query: 1994 GFVLSADR--CVPLNNGCGCWANGTYHEAGS----------EFWADGTCSQWCR-CG--- 2037
++ C + C A AGS + W DG+ SQ CR C
Sbjct: 106 ALAKASPEGHCFAMWQ-CQLQAGSANASAGSLEECCARPWGQSWWDGS-SQACRSCSSRH 163
Query: 2038 -PGGGS--LVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQG 2094
PG S + P + +G++ QH +P +T C +W HY T DG + F G
Sbjct: 164 LPGSASSPALLQPLAGAVGQLWS-----QHQ-RPSAT--CASWSGFHYRTFDGRHYHFLG 215
Query: 2095 TCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQ 2154
C YLL+ + V + R Q + + VT+ P ++
Sbjct: 216 RCTYLLAGAAD------STWAVHLTPGDRCPQP-GHCQRVTM------------GPEEVL 256
Query: 2155 VDGVFVALPFQL-----DSLLHA---HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYA 2206
+ V++ QL LLH G +V++ G+ + D + + V
Sbjct: 257 IQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDRTGSISISVDHELW 316
Query: 2207 ASLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQ-GCGEC--VSKPCPSPCT 2255
GLCG YN P DD GG A W++ G++ GC + V++ C
Sbjct: 317 GQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSESGCLDAVEVAQGCDPLGL 376
Query: 2256 PEQQESFG-----GPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQ-------VQG 2303
+ G D C + +GP CH V PA+Y + CL C +G
Sbjct: 377 IDADVEPGHLRAEAQDVCHQL--LEGPFGQCHAQVSPAEYHEACLFAYCAGAMAGSGQEG 434
Query: 2304 HPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSL--SA 2361
+C A+YV AC + WR+P FC CP Y C CP SC ++
Sbjct: 435 RQQAVCATFASYVQACARRHIHI-RWRKPGFCERLCPGGQLYSDCVSLCPPSCEAVGQGE 493
Query: 2362 PEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGP 2421
E C C GC C G +G CVP C C Y + + PG + C
Sbjct: 494 EESCREECVSGCECPRGLFWNGTLCVPAAHCPC------YYCRQRYVPGDTVRQLC---- 543
Query: 2422 GGHVTCQEGAACGPHEECRLEDGVQACHATGC-GRCLANGGIHYITLDGRVYDLHG--SC 2478
C DG C C C G HY+T DGR Y G C
Sbjct: 544 ---------------NPCVCRDGRWHCAQALCPAECAVGGDGHYLTFDGRSYSFWGGQGC 588
Query: 2479 SYVLAQVCHPKPGDEDFSIVLEKNA--AGD-LQRLLVTVAGQVVSLAQGQQVTVDGEAVA 2535
Y L Q I+LE A AG L + V++ + L V V+G+ V
Sbjct: 589 RYSLVQ----DYVKGQLLILLEHGACDAGSCLHAISVSLEDTHIQLRDSGAVLVNGQDVG 644
Query: 2536 LP-VAVGRVRVTAEGRNMVLQTTKGLRLLFD-GDAHLLMSIPSPFRGRLCGLCGNFNGNW 2593
LP + + V +L G ++L+ D +++ ++ GLCG F N
Sbjct: 645 LPWIGAEGLSVRRASSAFLLLRWPGAQVLWGLSDPVAYITLDPRHAHQVQGLCGTFTQNQ 704
Query: 2594 SDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQL 2653
DDF+ P G +S+ F + ++ G + E C + AC L
Sbjct: 705 QDDFLTPAGDVETSIAAFASKFQVAGKGRCPSEDSAL--LSPCTTHSQRHAFAEAACAIL 762
Query: 2654 RNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRT 2713
+ F C ++ ++ +C+ +C LC L+AY C G A PWR
Sbjct: 763 HS--SVFQECHRLVDKEPFYLRCLAAVCGCDPGSDCLCPVLSAYARRCAQEG-ASPPWRN 819
Query: 2714 DSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLS-QGVCIPVQ 2772
+ CP+ CP Y C C C G C GC C L +G C+P
Sbjct: 820 QTLCPVMCPGGQEYRECAPACGQHCGKPED-CGELGSCVAGCNCPLGLLWDPEGQCVPPS 878
Query: 2773 DCGCTHNG-RYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWAT 2831
C C RY P ++++ +C+ RC C C A CP C R
Sbjct: 879 LCPCQLGARRYAPGSATM--KECN-RCICQERGLWNCTARHCPSQAFC-----PRELVYA 930
Query: 2832 RGLCVL---SVGANLTTFDGAR-GATTSPGVYELSSRC--PGL---QNTIPWYRVVAEVQ 2882
G C+L S AN + G+ G PG L RC P L +++ WY A +Q
Sbjct: 931 PGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLLDERCVPPDLCPCRHSGQWYLPNATIQ 990
Query: 2883 ------ICH------------GKTEAVGQVHIFFQDGMVTLTP----------------- 2907
+C G+ +A G H DG+ P
Sbjct: 991 EDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREASGLFTV 1050
Query: 2908 -------------------------------NKGVWVNGLRVDLPAEKLASVSVSRTPDG 2936
+ V VNG+ V P R
Sbjct: 1051 SAQNLPCGASGLTCTKALAVRLEGTVVHMLRGRAVTVNGVSVTPPKVYTGPGLSLRRAGL 1110
Query: 2937 SLLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHDSQ------EKP 2990
LL+ G+ + +V V +S G++ G CG+FDGD +ND Q +
Sbjct: 1111 FLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAEL 1170
Query: 2991 AMEKWRAQDFSP 3002
A WR P
Sbjct: 1171 AAHSWRLSPLCP 1182
Score = 196 bits (497), Expect = 4e-49
Identities = 164/561 (29%), Positives = 228/561 (40%), Gaps = 55/561 (9%)
Query: 2254 CTPEQQESFGGPDACGVI-SATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAV 2312
C P + G P+ CG + S G P L P L CQ+ P
Sbjct: 836 CAPACGQHCGKPEDCGELGSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARR--YAPGS 893
Query: 2313 ATYVAACQAAGAQLGEWR-RPDFCPLQ--CPAHSHYELCGDSCPVSCPSLSAPEGCESAC 2369
AT + + G W CP Q CP Y +C ++C S SA C +
Sbjct: 894 ATMKECNRCICQERGLWNCTARHCPSQAFCPRELVY--APGACLLTCDSPSANHSCPAGS 951
Query: 2370 REGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQE 2429
+GCVC G VL + CVP C C H G++Y P + C C
Sbjct: 952 TDGCVCPPGTVLLDERCVPPDLCPCRHSGQWY------LPNATIQEDCN-------VC-- 996
Query: 2430 GAACGPHEECRLEDGVQACHATG---CGRCLANGGIHYITLDGRVYDLHGSCSYVLAQVC 2486
CR + H TG GRC A+G HY+T DG + G+C Y+L +
Sbjct: 997 --------VCR----GRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREA 1044
Query: 2487 HPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVSLAQGQQVTVDGEAVALP-VAVG-RVR 2544
++ + + L V + G VV + +G+ VTV+G +V P V G +
Sbjct: 1045 SGLFTVSAQNLPCGASGLTCTKALAVRLEGTVVHMLRGRAVTVNGVSVTPPKVYTGPGLS 1104
Query: 2545 VTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSA 2604
+ G ++L T GL LL+DG +L+ + FRGR+ GLCG+F+G+ S+D G
Sbjct: 1105 LRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVL 1164
Query: 2605 ASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQ 2664
+ E +WR S C E G P + A + + CG L P F C
Sbjct: 1165 EPTAELAAHSWRL---SPLCPEP-GDLPHPCTMNTHRAGW-ARARCGALLQPL--FTLCH 1217
Query: 2665 AVLSPSEYFRQCVYDLCA--QKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCP 2722
A + P +++ C+YD C GD LC ++A Y C G V+ WR+ C L C
Sbjct: 1218 AEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADECARHGHHVR-WRSQELCSLQCE 1276
Query: 2723 AHSHYSICTRTCQGSCAALSGLTGC---TTRCFEGCECDDRFLLSQGVCIPVQDCGCTHN 2779
Y C TC +C G C EGC C + LL G C+ C C
Sbjct: 1277 GGQVYEACGPTCPPTCHEQHPEPGWHCQVVACVEGCFCPEGTLLHGGACLEPASCPCEWG 1336
Query: 2780 GRYLPVNSSLLTSDCSERCSC 2800
P S+L DC C+C
Sbjct: 1337 RNSFP-PGSVLQKDCG-NCTC 1355
Score = 83.2 bits (204), Expect = 4e-15
Identities = 79/281 (28%), Positives = 98/281 (34%), Gaps = 43/281 (15%)
Query: 1417 NSWEEVVPDSPCLPPTPCPPGSEDCIPSH----------KCPPELEKKYQKEEFC----- 1461
+ W E P PCLPP+ P S + H P L + + C
Sbjct: 4526 SEWSEWSPCGPCLPPSALAPASRTALEEHWLRDPTGLSPTLAPLLASEQHRHRLCLDPAT 4585
Query: 1462 -----GLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSN---IHAYVSACQ 1513
G T PLS DP C + L + CS + +
Sbjct: 4586 GRPWTGAPHLCTAPLSQQRLCPDPGACPDSCQWSLWGPWSPCQVPCSGGFRLRWREAEAL 4645
Query: 1514 AAGGHVEPWRTETFCPMECPPNSHYEL-----CADTCSLGCSALSAPPQCQDG-CAEGCQ 1567
GG EPW E+ CP + CA+ C C+ L QC G C GC+
Sbjct: 4646 CGGGCREPWAQESCNGGPCPECEAQDTVFTLDCANQCPHSCADLWDRVQCLQGPCRPGCR 4705
Query: 1568 CDSGFLYNGQACVPIQQCGC----YHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEHS 1623
C G L CVPI C C + P Q V +D C Q CTC + +VC
Sbjct: 4706 CPPGQLVQDGRCVPISSCRCGLPSANASWELAPAQAVQLD-C-QNCTC-VNESLVCPHQE 4762
Query: 1624 CKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGV 1664
C V P SC PC G T TC +GG GV
Sbjct: 4763 C---PVLGPWSAWSSC--SAPCGGGTMERHRTC--EGGPGV 4796
Score = 79.3 bits (194), Expect = 5e-14
Identities = 99/366 (27%), Positives = 131/366 (35%), Gaps = 100/366 (27%)
Query: 1419 WEEV-VPDSPCLPPTPCPPGS--ED--CIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSS 1473
W+ V PC P CPPG +D C+P C CGL S+ ++
Sbjct: 4690 WDRVQCLQGPCRPGCRCPPGQLVQDGRCVPISSCR------------CGLPSA-----NA 4732
Query: 1474 CHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYV-------SACQA--AGGHVEPWRT 1524
+L Q DC C+ N S++C + V S+C A GG +E RT
Sbjct: 4733 SWELAPAQAVQLDCQNCTCV---NESLVCPHQECPVLGPWSAWSSCSAPCGGGTMERHRT 4789
Query: 1525 -------------ETF---------CPMECPPNSHYELCADTCSLGCSALSAPPQC-QDG 1561
+T CP ECPP CA +C C L C Q+
Sbjct: 4790 CEGGPGVAPCQAQDTEQRQECNLQPCP-ECPPGQVLSACATSCPCLCWHLQPGAICVQEP 4848
Query: 1562 CAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYE------------PEQTVLIDNCRQQC 1609
C GC C G L + CVP C C + + + P TVL NC +C
Sbjct: 4849 CQPGCGCPGGQLLHNGTCVPPTACPCTQHSLPWGLTLTLEEQAQELPPGTVLTRNC-TRC 4907
Query: 1610 TCHAGKGMVCQEHSCK--PGQVCQ--PSGGILSC----------VTKDPC-----HGVTC 1650
CH G C C+ PG+ Q G + C T+ C G C
Sbjct: 4908 VCHGG-AFSCSLVDCQVPPGETWQQVAPGELGLCEQTCLEMNATKTQSNCSSARASGCVC 4966
Query: 1651 RPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQ 1710
+P + G C+P CW G PH ++Q C L +G P V TQ
Sbjct: 4967 QPGHF---RSQAGPCVPEDHCECWHLGRPHLPG-----SEWQEACESCLCLSGRP-VCTQ 5017
Query: 1711 GLTPFT 1716
+P T
Sbjct: 5018 HCSPLT 5023
Score = 75.1 bits (183), Expect = 1e-12
Identities = 129/543 (23%), Positives = 175/543 (32%), Gaps = 127/543 (23%)
Query: 737 SPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSG-RPCVEGCVCLPGFVASGGACVP 795
+P C CPA C CP C+ C + C +GC C G + G CVP
Sbjct: 4054 NPMPCEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVP 4113
Query: 796 ASSCGCT-FQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLL 854
C CT QG APG + HQ C + CS Q G L
Sbjct: 4114 IGHCDCTDAQGHSWAPGSQ-----------------HQDACNN---------CSCQAGQL 4147
Query: 855 GCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGS 914
C T Q P + ++ + C++ SCG FR S
Sbjct: 4148 SC------TAQPCPPPTHCAWS--HWSAWSPCSH----SCGPRGQQSRFR--------SS 4187
Query: 915 QTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTD 974
+ S+ R E + + P L + L G+ Q + V+ D
Sbjct: 4188 TSGSWAPECREEQSQSQPCPQPSCPPLCLQGTRSRTLGDSWLQGECQRCSCTPEGVICED 4247
Query: 975 FGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGG---QAANALAFGNS 1031
V W + SS+++ CG G+ A R ++ L
Sbjct: 4248 TECAVPEAWT------LWSSWSDCPVS-CGG--GNQVRTRACRAAAPHHRSPPCLGPDTQ 4298
Query: 1032 WQEETRPG----------------CG---ATEPGDCPKLDSLVAQQLQSKNECGILADPK 1072
+++ PG CG A+ G CP L+A+ + N + D +
Sbjct: 4299 TRQQPCPGLLEACSWGPWGPCSRSCGPGLASRSGSCP---CLMAKADPTCNSTFLHLDTQ 4355
Query: 1073 GPFRECHSKLDPQGAVRDCVYD------RC---LLPGQ----SGPLCDALATYAAACQAA 1119
G C+S P+ +CV+ RC +L Q GP A A C
Sbjct: 4356 G----CYSGPCPE----ECVWSSWSSWTRCSCRVLVQQRYRHQGPASRG-ARAGAPCTRL 4406
Query: 1120 GATVHPWRSEELCPLSCPPHSHYEACSYGCP------LS---CGDLPVPGGCGSECHEGC 1170
P SC P + AC C LS C DLP C GC
Sbjct: 4407 DGHFRPCLISNCSEDSCTPPFEFHACGSPCAGLCATHLSHQLCQDLP-------PCQPGC 4459
Query: 1171 VCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGP----GCDSLCHCQEGGLVSCES 1226
C +G C+P C C H G T PG GC C C+ G L C S
Sbjct: 4460 YCPKGLLEQAGGCIPPEECNCWHTSA-AGAGMTLAPGDRLQLGCKE-CECRRGEL-HCTS 4516
Query: 1227 SSC 1229
C
Sbjct: 4517 QGC 4519
Score = 74.7 bits (182), Expect = 1e-12
Identities = 40/122 (32%), Positives = 50/122 (40%), Gaps = 14/122 (11%)
Query: 1133 PLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCV 1192
P CP + C+ G P SC +L P G CH GC C G L C+P C C
Sbjct: 3087 PGMCPRDKQWLDCAQG-PASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCA 3145
Query: 1193 HQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCG----------PHEACQPSGGSL 1242
H+G +PPG T C++ C C G + +C S C P C S G
Sbjct: 3146 HEGHLYPPGSTVV--RPCEN-CSCVSGLIANCSSWPCAEGEPTWSPWTPWSQCSASCGPA 3202
Query: 1243 GC 1244
C
Sbjct: 3203 RC 3204
Score = 69.7 bits (169), Expect = 4e-11
Identities = 41/123 (33%), Positives = 48/123 (39%), Gaps = 13/123 (10%)
Query: 2336 PLQCPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCL 2395
P CP + C P SC LSAP G C GC C +G +L + CVP C C
Sbjct: 3087 PGMCPRDKQWLDCAQG-PASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCA 3145
Query: 2396 HDGRYYPLGEVFYPGPECERRCECGPG-----GHVTCQEG----AACGPHEECRLEDGVQ 2446
H+G YP G CE C C G C EG + P +C G
Sbjct: 3146 HEGHLYPPGSTVV--RPCE-NCSCVSGLIANCSSWPCAEGEPTWSPWTPWSQCSASCGPA 3202
Query: 2447 ACH 2449
CH
Sbjct: 3203 RCH 3205
Score = 68.6 bits (166), Expect = 9e-11
Identities = 66/243 (27%), Positives = 86/243 (35%), Gaps = 41/243 (16%)
Query: 1406 GSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCP-------PELEKKYQKE 1458
G AGN SW P PC C G + + +++ P P + YQ+
Sbjct: 3941 GCGAGNC-----SWTSWAPWEPC--SRSCGVGQQRRLRAYRPPGPGGHWCPNILTAYQER 3993
Query: 1459 EFCGLLSSPT-------GPLSSCHKLVDPQGPLKDCIFDLCLGGGNL-SILCSNIHAYVS 1510
FC L + P P S C + C GG +L S CS+ +
Sbjct: 3994 RFCNLRACPVPGGWSRWSPWSWCDRS--------------CGGGQSLRSRSCSSPPSKNG 4039
Query: 1511 ACQAAGG-HVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDG--CAEGCQ 1567
AG H C CP CA+ C CS L CQD C +GC+
Sbjct: 4040 GAPCAGERHQARLCNPMPCEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCR 4099
Query: 1568 CDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEHSCKPG 1627
C G L CVPI C C + + D C C+C AG+ + C C P
Sbjct: 4100 CPKGSLEQDGGCVPIGHCDCTDAQGHSWAPGSQHQDAC-NNCSCQAGQ-LSCTAQPCPPP 4157
Query: 1628 QVC 1630
C
Sbjct: 4158 THC 4160
Score = 67.0 bits (162), Expect = 3e-10
Identities = 35/99 (35%), Positives = 42/99 (42%), Gaps = 3/99 (3%)
Query: 2718 PLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQDCGCT 2777
P CP + C + SCA LS G C GC C LL VC+P QDC C
Sbjct: 3087 PGMCPRDKQWLDCAQG-PASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCA 3145
Query: 2778 HNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPG 2816
H G P S+++ E CSC S C + C G
Sbjct: 3146 HEGHLYPPGSTVVRP--CENCSCVSGLIANCSSWPCAEG 3182
Score = 65.1 bits (157), Expect = 1e-09
Identities = 36/100 (36%), Positives = 45/100 (45%), Gaps = 3/100 (3%)
Query: 1529 PMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCY 1588
P CP + + CA + C+ LSAP C GC C SG L CVP Q C C
Sbjct: 3087 PGMCPRDKQWLDCAQGPA-SCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCA 3145
Query: 1589 HNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEHSCKPGQ 1628
H G Y P TV + C + C+C +G C C G+
Sbjct: 3146 HEGHLYPPGSTV-VRPC-ENCSCVSGLIANCSSWPCAEGE 3183
Score = 63.5 bits (153), Expect = 3e-09
Identities = 64/211 (30%), Positives = 76/211 (36%), Gaps = 54/211 (25%)
Query: 1844 GSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESF 1903
G+W W+ W C SC + R P P +G G P P
Sbjct: 2556 GAWAM--WE--AWGPCSVSCGGGHQSRQRSCVDP----PPKNG-GAPCPGASQERAP--- 2603
Query: 1904 FKGCVLDVCMGGGDRDILCKALASYVAA--CQAAGVVIEDWRAQVGCEITCPENSHYEVC 1961
C L C GG D C+ YV+A CQ V
Sbjct: 2604 ---CGLQPCSGGTD----CELGRVYVSADLCQKGLV------------------------ 2632
Query: 1962 GPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAG 2021
PPCP SC P + C G CVEGC+C G +L RC+PL+ C C G
Sbjct: 2633 -PPCPPSCLDPKANRS---CSGHCVEGCRCPPGLLLHDTRCLPLSE-CPCLVGEELKWPG 2687
Query: 2022 SEFWADGTCSQWCRCGPGGGSLVCTPASCGL 2052
F G CSQ C C G L+C P C L
Sbjct: 2688 VSFLL-GNCSQ-CVCEK--GELLCQPGGCPL 2714
Score = 62.4 bits (150), Expect = 7e-09
Identities = 66/227 (29%), Positives = 84/227 (37%), Gaps = 40/227 (17%)
Query: 1848 APGWDPLCWDECRGSCPT-----CPEDRLEQYE-GPGFCG-PLASGTGGPFTTCHAHVPP 1900
APG P W CP+ CP D ++ P C P G P++TC A
Sbjct: 2790 APGGGP-GWRSRSRLCPSPGDSSCPGDATQEEPCSPPVCPVPSIWGLWAPWSTCSAP--- 2845
Query: 1901 ESFFKGCVLDVCMGG-GDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHY- 1958
C GG R C +LA C D Q C CPEN +
Sbjct: 2846 -----------CDGGIQTRGRSCSSLAPGDTTCPGPHSQTRDCNTQP-CTAQCPENMLFR 2893
Query: 1959 --EVC---GPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWA 2013
E C G PCP C + P C G C GC C G L C+P + C C
Sbjct: 2894 SAEQCHQEGGPCPRLCLTQGP---GIECTGFCAPGCTCPPGLFLHNASCLP-RSQCPCQL 2949
Query: 2014 NGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLP 2060
+G + +G+ D +C+ C C G + CT C + CG P
Sbjct: 2950 HGQLYASGAMARLD-SCNN-CTC--VSGKMACTSERCPV--ACGWSP 2990
Score = 61.2 bits (147), Expect = 1e-08
Identities = 45/123 (36%), Positives = 50/123 (40%), Gaps = 18/123 (14%)
Query: 754 CGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGCTFQGL----QLA 809
C CP SC C PC GC C PG + G CVP SSC C +LA
Sbjct: 4678 CANQCPHSCADLWDRVQCLQGPCRPGCRCPPGQLVQDGRCVPISSCRCGLPSANASWELA 4737
Query: 810 PGQEVWADELCQRRCTCNGATHQVTCRDKQSCP------AGERCSVQNGLLGCYPDRFGT 863
P Q V D CQ CTC + C Q CP A CS G G +R T
Sbjct: 4738 PAQAVQLD--CQ-NCTC--VNESLVC-PHQECPVLGPWSAWSSCSAPCG--GGTMERHRT 4789
Query: 864 CQG 866
C+G
Sbjct: 4790 CEG 4792
Score = 59.3 bits (142), Expect = 6e-08
Identities = 44/141 (31%), Positives = 51/141 (36%), Gaps = 30/141 (21%)
Query: 1120 GATVHPWRSEELCPLSCPPHSHYEACSYG----------------CPLSCGDLPVPGGCG 1163
G P S+E P P S C G CP SC D C
Sbjct: 2590 GGAPCPGASQERAPCGLQPCSGGTDCELGRVYVSADLCQKGLVPPCPPSCLDPKANRSCS 2649
Query: 1164 SECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVS 1223
C EGC C G L CLPL+ C C+ PG +F G C S C C++G L+
Sbjct: 2650 GHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLG-NC-SQCVCEKGELL- 2706
Query: 1224 CESSSCGPHEACQPSGGSLGC 1244
CQP G L C
Sbjct: 2707 -----------CQPGGCPLPC 2716
Score = 59.3 bits (142), Expect = 6e-08
Identities = 36/129 (27%), Positives = 50/129 (38%), Gaps = 9/129 (6%)
Query: 1502 CSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHY---ELC---ADTCSLGCSALSAP 1555
CS++ + C T+ C +CP N + E C C C
Sbjct: 2857 CSSLAPGDTTCPGPHSQTRDCNTQP-CTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPG 2915
Query: 1556 PQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGK 1615
+C CA GC C G + +C+P QC C +G Y +D+C CTC +GK
Sbjct: 2916 IECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYASGAMARLDSC-NNCTCVSGK 2974
Query: 1616 GMVCQEHSC 1624
M C C
Sbjct: 2975 -MACTSERC 2982
Score = 58.2 bits (139), Expect = 1e-07
Identities = 73/259 (28%), Positives = 89/259 (34%), Gaps = 63/259 (24%)
Query: 1021 QAANALAFGNSWQEETRPGCGATEPGD-CPKLDSLVAQQLQSKNECGILADPK-----GP 1074
Q+ +A + +SW E PG T P D C + ++ Q Q +C DP GP
Sbjct: 3600 QSRSAGSRFSSW-ESLEPGEVVTGPCDNCTCVAGIL--QCQEVPDC---PDPGVWSSWGP 3653
Query: 1075 FRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPL 1134
+ +C +R RC P GP + C+ AG
Sbjct: 3654 WEDCSVSCGGGEQLRS---RRCARPPCPGPARQSRTCSTQVCREAG-------------- 3696
Query: 1135 SCPPHSHYEACS--YGCPLSCGDLPVPGGCGSE-CHEGCVCDEGFALSGESCLPLASCGC 1191
CP Y C GCP SC + GC SE C EGC C EG +C + C C
Sbjct: 3697 -CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLAC--VQECPC 3753
Query: 1192 VHQ--------GTYHPPGQTFYPGPGCDS---------LCHCQEGGLVSCESSSC----- 1229
V T PGQ PG DS C C G L SC C
Sbjct: 3754 VLTAWLLQELGATIGDPGQPLGPGDELDSGQTLRTSCGNCSCAHGKL-SCSLDDCFEADG 3812
Query: 1230 -----GPHEACQPSGGSLG 1243
P C S G LG
Sbjct: 3813 GFGPWSPWGPCSRSCGGLG 3831
Score = 57.0 bits (136), Expect = 3e-07
Identities = 40/138 (28%), Positives = 52/138 (37%), Gaps = 29/138 (21%)
Query: 1487 CIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCS 1546
C C GG + C YVSA G V P CPP+
Sbjct: 2604 CGLQPCSGGTD----CELGRVYVSADLCQKGLVPP----------CPPS----------- 2638
Query: 1547 LGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCR 1606
C A C C EGC+C G L + C+P+ +C C P + L+ NC
Sbjct: 2639 --CLDPKANRSCSGHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLGNC- 2695
Query: 1607 QQCTCHAGKGMVCQEHSC 1624
QC C G+ ++CQ C
Sbjct: 2696 SQCVCEKGE-LLCQPGGC 2712
Score = 56.2 bits (134), Expect = 5e-07
Identities = 34/107 (31%), Positives = 43/107 (40%), Gaps = 7/107 (6%)
Query: 1132 CPLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSE--CHEGCVCDEGFALSGESCLPLASC 1189
C CP C+ CP C DL C + C +GC C +G C+P+ C
Sbjct: 4058 CEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGHC 4117
Query: 1190 GCVH-QGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEAC 1235
C QG PG C++ C CQ G L SC + C P C
Sbjct: 4118 DCTDAQGHSWAPGSQHQ--DACNN-CSCQAGQL-SCTAQPCPPPTHC 4160
Score = 56.2 bits (134), Expect = 5e-07
Identities = 31/121 (25%), Positives = 47/121 (38%), Gaps = 10/121 (8%)
Query: 1512 CQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQD--GCAEGCQCD 1569
C GH P C P + C C+ C+ + CQD C GC C
Sbjct: 4403 CTRLDGHFRPCLISNCSEDSCTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCP 4462
Query: 1570 SGFLYNGQACVPIQQCGCYHN-----GVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEHSC 1624
G L C+P ++C C+H G+ P + + C+ +C C G+ + C C
Sbjct: 4463 KGLLEQAGGCIPPEECNCWHTSAAGAGMTLAPGDRLQL-GCK-ECECRRGE-LHCTSQGC 4519
Query: 1625 K 1625
+
Sbjct: 4520 Q 4520
Score = 55.1 bits (131), Expect = 1e-06
Identities = 56/211 (26%), Positives = 68/211 (32%), Gaps = 57/211 (27%)
Query: 1844 GSWRAPGWDPLC-WDECRGSCPTCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPES 1902
G RA GW P W C SC R + P PP+
Sbjct: 3248 GCDRAGGWGPWGPWSHCSRSCGGGLRSRTRACDQP---------------------PPQG 3286
Query: 1903 FFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCG 1962
D C G + +C+AL V C A E + Y CG
Sbjct: 3287 LG-----DYCEGPRAQGEVCQALPCPVTNCTAI------------------EGAEYSPCG 3323
Query: 1963 PPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNG-CGC--WANGTYHE 2019
PPCP SC C C GC C G VLS++ + + G C C G H
Sbjct: 3324 PPCPRSCDDLVH------CVWRCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHH 3377
Query: 2020 AGSEFWADGTCSQWCRCGPGGGSLVCTPASC 2050
G+ C+ C C G L CT C
Sbjct: 3378 PGARLARPDGCNH-CTCLE--GRLNCTDLPC 3405
Score = 55.1 bits (131), Expect = 1e-06
Identities = 69/260 (26%), Positives = 91/260 (35%), Gaps = 39/260 (15%)
Query: 1812 AVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWG---GSWRAPGWDPLCWDECRGSCPTCPE 1868
A C + + P N P+ T P P G G+ W P W+ C SC +
Sbjct: 3913 ANCTMGDPLQERPCN---LPSCTELPVCPGPGCGAGNCSWTSWAP--WEPCSRSCGVGQQ 3967
Query: 1869 DRLEQYEGPGFCGP-----LASGTGGPFTTCHAHVPPESFFKGCVLDVC---MGGGD--R 1918
RL Y PG G L + F A P + + C GGG R
Sbjct: 3968 RRLRAYRPPGPGGHWCPNILTAYQERRFCNLRACPVPGGWSRWSPWSWCDRSCGGGQSLR 4027
Query: 1919 DILCKALASYVAACQAAGVVIEDWRAQ----VGCEITCPENSHYEVCGPPCPASCPSPAP 1974
C + S AG E +A+ + CE CP C CP C +
Sbjct: 4028 SRSCSSPPSKNGGAPCAG---ERHQARLCNPMPCEAGCPAGMEVVTCANRCPRRC---SD 4081
Query: 1975 LTTPAVCEGP--CVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQ 2032
L VC+ C +GC+C G + CVP+ + C C +A WA G+ Q
Sbjct: 4082 LQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGH-CDC------TDAQGHSWAPGSQHQ 4134
Query: 2033 WC--RCGPGGGSLVCTPASC 2050
C G L CT C
Sbjct: 4135 DACNNCSCQAGQLSCTAQPC 4154
Score = 54.7 bits (130), Expect = 1e-06
Identities = 68/233 (29%), Positives = 81/233 (34%), Gaps = 57/233 (24%)
Query: 2245 CVSKPCP------SPCTPEQQESFG-GPDAC----------GVISATDGPL----APCHG 2283
C S PC SP TP Q S GP C + +T PL P
Sbjct: 3174 CSSWPCAEGEPTWSPWTPWSQCSASCGPARCHRHRFCARSPSAVPSTVAPLPLPATPTPL 3233
Query: 2284 LVPPAQYFQGCLLDACQVQGHPGGLCP----------AVATYVAACQAAGAQ-LGEW--- 2329
P + CLL C G G P + + AC Q LG++
Sbjct: 3234 CSGPEAEEEPCLLQGCDRAGGWGPWGPWSHCSRSCGGGLRSRTRACDQPPPQGLGDYCEG 3293
Query: 2330 --RRPDFCP-LQCPAHS-------HYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGF 2379
+ + C L CP + Y CG CP SC L C C+ GC C G
Sbjct: 3294 PRAQGEVCQALPCPVTNCTAIEGAEYSPCGPPCPRSCDDLVH---CVWRCQPGCYCPPGQ 3350
Query: 2380 VLS--GDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEG 2430
VLS G CV G C CL G+ +PG R C H TC EG
Sbjct: 3351 VLSSNGAICVQPGHCSCLD----LLTGQRHHPGARLARPDGC---NHCTCLEG 3396
Score = 54.7 bits (130), Expect = 1e-06
Identities = 38/128 (29%), Positives = 48/128 (37%), Gaps = 17/128 (13%)
Query: 741 CPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCG 800
CP CP C +CP C + C PC GC C G + G CVP ++C
Sbjct: 4815 CP-ECPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTACP 4873
Query: 801 CTFQGL-------------QLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERC 847
CT L +L PG + + C RC C+G + D Q P
Sbjct: 4874 CTQHSLPWGLTLTLEEQAQELPPGTVLTRN--C-TRCVCHGGAFSCSLVDCQVPPGETWQ 4930
Query: 848 SVQNGLLG 855
V G LG
Sbjct: 4931 QVAPGELG 4938
Score = 54.3 bits (129), Expect = 2e-06
Identities = 37/126 (29%), Positives = 47/126 (37%), Gaps = 9/126 (7%)
Query: 2717 CPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTR--CFEGCECDDRFLLSQGVCIPVQDC 2774
C CPA C C C+ L C C +GC C L G C+P+ C
Sbjct: 4058 CEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGHC 4117
Query: 2775 GCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATRGL 2834
CT + S C+ CSC + L+C A CPP C A + W+
Sbjct: 4118 DCTDAQGHSWAPGSQHQDACN-NCSCQAGQ-LSCTAQPCPPPTHC-----AWSHWSAWSP 4170
Query: 2835 CVLSVG 2840
C S G
Sbjct: 4171 CSHSCG 4176
Score = 53.9 bits (128), Expect = 2e-06
Identities = 61/243 (25%), Positives = 80/243 (32%), Gaps = 33/243 (13%)
Query: 2226 AVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLV 2285
A GG P GW+ ++ C CP T E+ S P C P+ GL
Sbjct: 2790 APGGGP-GWR-SRSRLCPSPGDSSCPGDATQEEPCS---PPVC--------PVPSIWGLW 2836
Query: 2286 PPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHY 2345
P Q +G C ++A C +Q + C QCP + +
Sbjct: 2837 APWSTCSAPCDGGIQTRGRS---CSSLAPGDTTCPGPHSQTRDCNTQP-CTAQCPENMLF 2892
Query: 2346 ---ELC---GDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGR 2399
E C G CP C + C C GC C G L +C+P QC C G+
Sbjct: 2893 RSAEQCHQEGGPCPRLCLTQGPGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQ 2952
Query: 2400 YYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLAN 2459
Y G + R C + TC G E C + G C N
Sbjct: 2953 LYASGAM-------ARLDSC---NNCTCVSGKMACTSERCPVACGWSPWTLWSLCSCSCN 3002
Query: 2460 GGI 2462
GI
Sbjct: 3003 VGI 3005
Score = 53.5 bits (127), Expect = 3e-06
Identities = 57/200 (28%), Positives = 70/200 (35%), Gaps = 28/200 (14%)
Query: 1480 PQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVE--PWRTETFCPMECPPNSH 1537
P GP C D+CLG + S CS G H + P + + +C
Sbjct: 3477 PWGPWSPC--DMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTDCGGGQS 3534
Query: 1538 YELCADTCSLGCSALSAPPQCQDG---CAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYY 1594
C C C LS CQ G C C C G L CVP C C Y
Sbjct: 3535 LHPCGQPCPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRC-----QY 3589
Query: 1595 EPEQTVLIDNCRQQCTCHAGKGMVCQEHSCKPGQV-------CQPSGGILSC--VTKDPC 1645
+P + +N + AG E S +PG+V C GIL C V P
Sbjct: 3590 QPGAMGIPENQSRS----AGSRFSSWE-SLEPGEVVTGPCDNCTCVAGILQCQEVPDCPD 3644
Query: 1646 HGV--TCRPQETCKEQGGQG 1663
GV + P E C G G
Sbjct: 3645 PGVWSSWGPWEDCSVSCGGG 3664
Score = 53.5 bits (127), Expect = 3e-06
Identities = 59/224 (26%), Positives = 77/224 (34%), Gaps = 40/224 (17%)
Query: 2232 AGWQVGGAQGCG-ECVSKPC--PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPA 2288
A W++ AQ +C + C S P Q+ GP SA APC G
Sbjct: 4732 ASWELAPAQAVQLDCQNCTCVNESLVCPHQECPVLGP-----WSAWSSCSAPCGG----- 4781
Query: 2289 QYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELC 2348
G + +G PG VA CQA + + CP +CP C
Sbjct: 4782 ----GTMERHRTCEGGPG---------VAPCQAQDTEQRQECNLQPCP-ECPPGQVLSAC 4827
Query: 2349 GDSCPVSCPSLSAPEGC-ESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPL---- 2403
SCP C L C + C+ GC C G +L TCVP C C + L
Sbjct: 4828 ATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTACPCTQHSLPWGLTLTL 4887
Query: 2404 ---GEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDG 2444
+ PG R C C GA +C++ G
Sbjct: 4888 EEQAQELPPGTVLTRNCT-----RCVCHGGAFSCSLVDCQVPPG 4926
Score = 52.8 bits (125), Expect = 5e-06
Identities = 27/81 (33%), Positives = 33/81 (40%), Gaps = 2/81 (2%)
Query: 2734 CQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSD 2793
C SC C+ C EGC C LL C+P+ +C C S L +
Sbjct: 2635 CPPSCLDPKANRSCSGHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLGN 2694
Query: 2794 CSERCSCSSSSGLTCQAAGCP 2814
CS+ C C L CQ GCP
Sbjct: 2695 CSQ-CVCEKGE-LLCQPGGCP 2713
Score = 52.8 bits (125), Expect = 5e-06
Identities = 35/118 (29%), Positives = 44/118 (37%), Gaps = 18/118 (15%)
Query: 741 CPLSCPANSRY---ELC---GPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACV 794
C CP N + E C G CP C C+G C GC C PG +C+
Sbjct: 2882 CTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPGIECTGF-CAPGCTCPPGLFLHNASCL 2940
Query: 795 PASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNG 852
P S C C G +++A R +CN TC + ERC V G
Sbjct: 2941 PRSQCPCQLHG-------QLYASGAMARLDSCNNC----TCVSGKMACTSERCPVACG 2987
Score = 52.8 bits (125), Expect = 5e-06
Identities = 58/233 (24%), Positives = 75/233 (32%), Gaps = 55/233 (23%)
Query: 2252 SPCTPE--------QQESFGGPDACGVISATD--GPLAPCHGLVPPAQYFQGCLLDACQV 2301
+PCT E Q+E+ C V A GP +PC + + + C
Sbjct: 3445 APCTGEAGEAGAQHQREACPSYATCPVDGAWGPWGPWSPCDMCLGQSHRSRACSRPPTPE 3504
Query: 2302 QGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSA 2361
G P CP T CQ Q + C CG CP SC LS
Sbjct: 3505 GGRP---CPGNHTQSRPCQENSTQCTD----------CGGGQSLHPCGQPCPRSCQDLSP 3551
Query: 2362 PEGCESA---CREGCVCDAGFVLSGDTCVPVGQCGCLHD--------------GRYYPLG 2404
C+ C+ C C G + CVP C C + G +
Sbjct: 3552 GSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRCQYQPGAMGIPENQSRSAGSRFSSW 3611
Query: 2405 EVFYPGP----ECERRCECGPGGHVTCQEGAAC---------GPHEECRLEDG 2444
E PG C+ C C G + CQE C GP E+C + G
Sbjct: 3612 ESLEPGEVVTGPCD-NCTC-VAGILQCQEVPDCPDPGVWSSWGPWEDCSVSCG 3662
Score = 52.4 bits (124), Expect = 7e-06
Identities = 64/241 (26%), Positives = 85/241 (35%), Gaps = 35/241 (14%)
Query: 1040 CGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLP 1099
CG +L A QL +N + P +EC L P A + C P
Sbjct: 4725 CGLPSANASWELAPAQAVQLDCQNCTCVNESLVCPHQEC-PVLGPWSA-----WSSCSAP 4778
Query: 1100 GQSGPL-----CDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCG 1154
G + C+ A CQA + + CP CPP AC+ CP C
Sbjct: 4779 CGGGTMERHRTCEG-GPGVAPCQAQDTEQRQECNLQPCP-ECPPGQVLSACATSCPCLCW 4836
Query: 1155 DLPVPGGCGSE-CHEGCVCDEGFALSGESCLPLASCGCVHQG-------TYHPPGQTFYP 1206
L C E C GC C G L +C+P +C C T Q P
Sbjct: 4837 HLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTACPCTQHSLPWGLTLTLEEQAQELPP 4896
Query: 1207 GP----GCDSLCHCQEGGLVSCESSSC--GPHEACQP-SGGSLG-----CVAVGSSTCQA 1254
G C + C C GG SC C P E Q + G LG C+ + ++ Q+
Sbjct: 4897 GTVLTRNC-TRCVC-HGGAFSCSLVDCQVPPGETWQQVAPGELGLCEQTCLEMNATKTQS 4954
Query: 1255 S 1255
+
Sbjct: 4955 N 4955
Score = 52.0 bits (123), Expect = 9e-06
Identities = 42/140 (30%), Positives = 48/140 (34%), Gaps = 27/140 (19%)
Query: 1094 DRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSC 1153
D C P G +C AL C A + Y C CP SC
Sbjct: 3289 DYCEGPRAQGEVCQALPCPVTNCTAIEG------------------AEYSPCGPPCPRSC 3330
Query: 1154 GDLPVPGGCGSECHEGCVCDEGFALS--GESCLPLASCGCVH--QGTYHPPGQTFYPGPG 1209
DL C C GC C G LS G C+ C C+ G H PG G
Sbjct: 3331 DDLV---HCVWRCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDG 3387
Query: 1210 CDSLCHCQEGGLVSCESSSC 1229
C+ C C EG L +C C
Sbjct: 3388 CNH-CTCLEGRL-NCTDLPC 3405
Score = 51.6 bits (122), Expect = 1e-05
Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 12/110 (10%)
Query: 2335 CPLQCPAHSHYELCGDSCPVSCPSLSAPEGCES--ACREGCVCDAGFVLSGDTCVPVGQC 2392
C CPA C + CP C L C+ C++GC C G + CVP+G C
Sbjct: 4058 CEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGHC 4117
Query: 2393 GCLHDGRYYPLGEVFYPGPECE---RRCECGPGGHVTCQEGAACGPHEEC 2439
C G + PG + + C C G ++C C P C
Sbjct: 4118 DCTD-----AQGHSWAPGSQHQDACNNCSC-QAGQLSC-TAQPCPPPTHC 4160
Score = 50.8 bits (120), Expect = 2e-05
Identities = 38/116 (32%), Positives = 46/116 (39%), Gaps = 17/116 (14%)
Query: 715 CRGLSAYAQACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGR 774
C G A + C L V NC + + Y CGP CP SC+ +C R
Sbjct: 3291 CEGPRAQGEVCQALPCPV------TNC--TAIEGAEYSPCGPPCPRSCDDLV---HCVWR 3339
Query: 775 PCVEGCVCLPGFVAS--GGACVPASSCGC--TFQGLQLAPGQEVWADELCQRRCTC 826
C GC C PG V S G CV C C G + PG + + C CTC
Sbjct: 3340 -CQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGC-NHCTC 3393
Score = 50.4 bits (119), Expect = 3e-05
Identities = 41/133 (30%), Positives = 50/133 (37%), Gaps = 6/133 (4%)
Query: 1965 CPASCPSPAPLTTPAVCEGPCVEGCQCDAG-FVLSADRCVPLNNGCGCWANGTYHEAGSE 2023
C +C T + C GC C G F A CVP ++ C CW G H GSE
Sbjct: 4940 CEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDH-CECWHLGRPHLPGSE 4998
Query: 2024 FWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYV 2083
W + S C G + C+P +C GE L P C P E P
Sbjct: 4999 -WQEACESCLCLSGRPVCTQHCSPLTCAQGEEMVLEPG---SCCPSCRREAPEEQSPSCQ 5054
Query: 2084 TLDGHRFDFQGTC 2096
L R +GTC
Sbjct: 5055 LLTELRNFTKGTC 5067
Score = 49.7 bits (117), Expect = 4e-05
Identities = 22/46 (47%), Positives = 25/46 (54%), Gaps = 1/46 (2%)
Query: 756 PACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGC 801
P CP SC A +CSG CVEGC C PG + C+P S C C
Sbjct: 2633 PPCPPSCLDPKANRSCSGH-CVEGCRCPPGLLLHDTRCLPLSECPC 2677
Score = 48.5 bits (114), Expect = 1e-04
Identities = 27/77 (35%), Positives = 32/77 (41%), Gaps = 5/77 (6%)
Query: 2352 CPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGP 2411
CP SC A C C EGC C G +L C+P+ +C CL G F G
Sbjct: 2635 CPPSCLDPKANRSCSGHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLGN 2694
Query: 2412 ECERRCE-----CGPGG 2423
+ CE C PGG
Sbjct: 2695 CSQCVCEKGELLCQPGG 2711
Score = 47.4 bits (111), Expect = 2e-04
Identities = 34/130 (26%), Positives = 47/130 (36%), Gaps = 9/130 (6%)
Query: 2691 CRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQ--GSCAALSGLTG-- 2746
C SLA C + T C CP + + + Q G C L G
Sbjct: 2857 CSSLAPGDTTCPGPHSQTRDCNTQP-CTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPG 2915
Query: 2747 --CTTRCFEGCECDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSS 2804
CT C GC C L C+P C C +G+ L + ++ D C+C S
Sbjct: 2916 IECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQ-LYASGAMARLDSCNNCTCVSGK 2974
Query: 2805 GLTCQAAGCP 2814
+ C + CP
Sbjct: 2975 -MACTSERCP 2983
Score = 47.4 bits (111), Expect = 2e-04
Identities = 38/144 (26%), Positives = 52/144 (36%), Gaps = 19/144 (13%)
Query: 742 PLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGC 801
P CP + ++ C P SC +AP + + C GC C G + CVP C C
Sbjct: 3087 PGMCPRDKQWLDCAQG-PASCAELSAPRG-TNQTCHPGCHCPSGMLLLNNVCVPTQDCPC 3144
Query: 802 TFQGLQLAPGQEVWADELCQRRC-TCNGATHQVTCRDKQSCPAGE----------RCSVQ 850
+G PG V R C C+ + + C GE +CS
Sbjct: 3145 AHEGHLYPPGSTV------VRPCENCSCVSGLIANCSSWPCAEGEPTWSPWTPWSQCSAS 3198
Query: 851 NGLLGCYPDRFGTCQGSGDPHYVS 874
G C+ RF S P V+
Sbjct: 3199 CGPARCHRHRFCARSPSAVPSTVA 3222
Score = 47.0 bits (110), Expect = 3e-04
Identities = 36/126 (28%), Positives = 48/126 (38%), Gaps = 13/126 (10%)
Query: 2699 AACQAAGVAVKPWRTDSF----CPLHCPAHSHYSI--CTRTCQGSCAALSGLTGCTTR-C 2751
A G +PW +S CP C A C C SCA L C C
Sbjct: 4642 AEALCGGGCREPWAQESCNGGPCP-ECEAQDTVFTLDCANQCPHSCADLWDRVQCLQGPC 4700
Query: 2752 FEGCECDDRFLLSQGVCIPVQDCGC---THNGRYLPVNSSLLTSDCSERCSCSSSSGLTC 2808
GC C L+ G C+P+ C C + N + + + DC + C+C + S L C
Sbjct: 4701 RPGCRCPPGQLVQDGRCVPISSCRCGLPSANASWELAPAQAVQLDC-QNCTCVNES-LVC 4758
Query: 2809 QAAGCP 2814
CP
Sbjct: 4759 PHQECP 4764
Score = 47.0 bits (110), Expect = 3e-04
Identities = 60/230 (26%), Positives = 82/230 (35%), Gaps = 37/230 (16%)
Query: 640 WKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPF--- 696
W L G ++ CQ C C GQ H + C P C T P+
Sbjct: 4836 WHLQPGAICVQEPCQPGC-GCPGGQLLH---NGTCV-------PPTACPCTQHSLPWGLT 4884
Query: 697 --LEQCVYDL----CVVGGERLSLCRGLSAYAQACLELGISVGD-WRSPANCPLSCPANS 749
LE+ +L + +C G A++ + ++ + G+ W+ A L
Sbjct: 4885 LTLEEQAQELPPGTVLTRNCTRCVCHG-GAFSCSLVDCQVPPGETWQQVAPGELG----- 4938
Query: 750 RYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPG-FVASGGACVPASSCGCTFQGLQL 808
LC C N SNCS GCVC PG F + G CVP C C G
Sbjct: 4939 ---LCEQTC-LEMNATKTQSNCSSARA-SGCVCQPGHFRSQAGPCVPEDHCECWHLGRPH 4993
Query: 809 APGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYP 858
PG E W E C+ +G +C GE ++ G C P
Sbjct: 4994 LPGSE-W-QEACESCLCLSGRPVCTQHCSPLTCAQGEEMVLEPG--SCCP 5039
Score = 46.6 bits (109), Expect = 4e-04
Identities = 49/194 (25%), Positives = 65/194 (33%), Gaps = 31/194 (15%)
Query: 2699 AACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTR-CFEGCEC 2757
A CQA + CP CP S C +C C L C C GC C
Sbjct: 4797 APCQAQDTEQRQECNLQPCP-ECPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGC 4855
Query: 2758 DDRFLLSQGVCIPVQDCGCTHN-------------GRYLPVNSSLLTSDCSERCSCSSSS 2804
LL G C+P C CT + + LP ++LT +C+ RC C +
Sbjct: 4856 PGGQLLHNGTCVPPTACPCTQHSLPWGLTLTLEEQAQELP-PGTVLTRNCT-RCVCHGGA 4913
Query: 2805 GLTCQAAGC--PPGR-----------VCEVKAEARNCWATRGLCVLSVGANLTTFDGARG 2851
+C C PPG +CE N T+ C + + G
Sbjct: 4914 -FSCSLVDCQVPPGETWQQVAPGELGLCEQTCLEMNATKTQSNCSSARASGCVCQPGHFR 4972
Query: 2852 ATTSPGVYELSSRC 2865
+ P V E C
Sbjct: 4973 SQAGPCVPEDHCEC 4986
Score = 45.8 bits (107), Expect = 6e-04
Identities = 48/181 (26%), Positives = 65/181 (35%), Gaps = 25/181 (13%)
Query: 1900 PESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEIT----CPEN 1955
P S + C G +R C+ VA CQA +D + C + CP
Sbjct: 4768 PWSAWSSCSAPCGGGTMERHRTCEG-GPGVAPCQA-----QDTEQRQECNLQPCPECPPG 4821
Query: 1956 SHYEVCGPPCPASCPSPAPLTTPAVC-EGPCVEGCQCDAGFVLSADRCVPLNNGCGCWAN 2014
C CP C P A+C + PC GC C G +L CVP C C +
Sbjct: 4822 QVLSACATSCPCLCWHLQP---GAICVQEPCQPGCGCPGGQLLHNGTCVP-PTACPCTQH 4877
Query: 2015 G-------TYHEAGSEFWADGTCSQWC-RCGPGGGSLVCTPASCGL--GEVCGLLPSGQH 2064
T E E ++ C RC GG+ C+ C + GE + G+
Sbjct: 4878 SLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQVPPGETWQQVAPGEL 4937
Query: 2065 G 2065
G
Sbjct: 4938 G 4938
Score = 45.8 bits (107), Expect = 6e-04
Identities = 35/102 (34%), Positives = 41/102 (40%), Gaps = 15/102 (14%)
Query: 2352 CPVSCPSLSAPE---GCESACREGCVCDAG-FVLSGDTCVPVGQCGCLHDGRYYPLGEVF 2407
C +C ++A + C SA GCVC G F CVP C C H LG
Sbjct: 4940 CEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDHCECWH------LGRPH 4993
Query: 2408 YPGPECERRCE---CGPGGHVTCQEGA--ACGPHEECRLEDG 2444
PG E + CE C G V Q + C EE LE G
Sbjct: 4994 LPGSEWQEACESCLCLSGRPVCTQHCSPLTCAQGEEMVLEPG 5035
Score = 45.4 bits (106), Expect = 8e-04
Identities = 34/98 (34%), Positives = 43/98 (43%), Gaps = 12/98 (12%)
Query: 741 CP-LSCPANSRYELCGPACPTSCNGAAAPSNCSGR-PCVE-GCVCLPGFV-ASGGACVPA 796
CP +C ++ C P CP +C+ + C PC GC C G V S G CV
Sbjct: 1807 CPNATCSGELMFQPCAP-CPLTCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSEGWCVWP 1865
Query: 797 SSCGCTFQGLQLAPGQEVWAD-ELC------QRRCTCN 827
C C G + PGQ + AD +LC RRC N
Sbjct: 1866 RQCPCLVDGARYWPGQRIKADCQLCICQDGRPRRCRLN 1903
Score = 45.4 bits (106), Expect = 8e-04
Identities = 34/115 (29%), Positives = 44/115 (38%), Gaps = 13/115 (11%)
Query: 1949 EITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEG--PCVEGCQCDAGFVLSADRCVPLN 2006
E +C + CG PC C A + +C+ PC GC C G + A C+P
Sbjct: 4420 EDSCTPPFEFHACGSPCAGLC---ATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIPPE 4476
Query: 2007 NGCGCWANGTYHEAGSEFWADGTCSQWCR-CGPGGGSLVCTPASCGLGEVCGLLP 2060
C CW + + AG C+ C G L CT C GLLP
Sbjct: 4477 E-CNCW-HTSAAGAGMTLAPGDRLQLGCKECECRRGELHCTSQGCQ-----GLLP 4524
Score = 45.1 bits (105), Expect = 0.001
Identities = 37/120 (30%), Positives = 51/120 (42%), Gaps = 15/120 (12%)
Query: 1512 CQAAGGHVEPWRTETFCPMECPPNSH------YELCADTCSLGCSALSA----PPQCQDG 1561
C A G + R CP + PN+ ++ CA C L C +S PP G
Sbjct: 1786 CAALPGGLHSTRQTKPCPQDGCPNATCSGELMFQPCAP-CPLTCDDISGQVTCPPDWPCG 1844
Query: 1562 CAEGCQCDSGFLYNGQA-CVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQ 1620
+ GC C G + + CV +QC C +G Y P Q + D C Q C C G+ C+
Sbjct: 1845 -SPGCWCPEGQVLGSEGWCVWPRQCPCLVDGARYWPGQRIKAD-C-QLCICQDGRPRRCR 1901
Score = 45.1 bits (105), Expect = 0.001
Identities = 32/106 (30%), Positives = 40/106 (37%), Gaps = 15/106 (14%)
Query: 745 CPANSRYELCGPA--CPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSC--- 799
CPA Y C P CP SC C C EGC C G ACV C
Sbjct: 3697 CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLACVQECPCVLT 3756
Query: 800 -------GCTF--QGLQLAPGQEVWADELCQRRC-TCNGATHQVTC 835
G T G L PG E+ + + + C C+ A +++C
Sbjct: 3757 AWLLQELGATIGDPGQPLGPGDELDSGQTLRTSCGNCSCAHGKLSC 3802
Score = 45.1 bits (105), Expect = 0.001
Identities = 51/222 (22%), Positives = 68/222 (30%), Gaps = 73/222 (32%)
Query: 2245 CVSKPCPSPCT---------------PEQQESFGGPDACGVISATDGPLAPCHGLVPPAQ 2289
C S PCP C +Q+ GP + G + APC L
Sbjct: 4357 CYSGPCPEECVWSSWSSWTRCSCRVLVQQRYRHQGPASRGARAG-----APCTRL---DG 4408
Query: 2290 YFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCG 2349
+F+ CL+ C P + AG C H ++LC
Sbjct: 4409 HFRPCLISNCS----EDSCTPPFEFHACGSPCAGL--------------CATHLSHQLCQ 4450
Query: 2350 DSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYP 2409
D P C+ GC C G + C+P +C C H G P
Sbjct: 4451 DLPP---------------CQPGCYCPKGLLEQAGGCIPPEECNCWHTSA-AGAGMTLAP 4494
Query: 2410 GPECE---RRCECGPGG-HVTCQ------------EGAACGP 2435
G + + CEC G H T Q E + CGP
Sbjct: 4495 GDRLQLGCKECECRRGELHCTSQGCQGLLPLSEWSEWSPCGP 4536
Score = 44.7 bits (104), Expect = 0.001
Identities = 27/96 (28%), Positives = 38/96 (39%), Gaps = 14/96 (14%)
Query: 2348 CGDSCPVSCPSLSAPEGC-ESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEV 2406
C + CP SC L C + CR GC C G ++ CVP+ C C P
Sbjct: 4678 CANQCPHSCADLWDRVQCLQGPCRPGCRCPPGQLVQDGRCVPISSCRC-----GLPSANA 4732
Query: 2407 FY---PGPECERRCECGPGGHVTCQEGAACGPHEEC 2439
+ P + C+ + TC + PH+EC
Sbjct: 4733 SWELAPAQAVQLDCQ-----NCTCVNESLVCPHQEC 4763
Score = 44.3 bits (103), Expect = 0.002
Identities = 147/647 (22%), Positives = 199/647 (30%), Gaps = 152/647 (23%)
Query: 2245 CVSKPCPSP----CTPEQQ--ESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLL-- 2296
C +PC P C ++Q + GP +C +SA G CH P G LL
Sbjct: 3077 CGLQPCAGPVPGMCPRDKQWLDCAQGPASCAELSAPRGTNQTCH---PGCHCPSGMLLLN 3133
Query: 2297 --------DACQVQGH---PGGL-------CPAVATYVAACQAAGAQLGE-----WRRPD 2333
C +GH PG C V+ +A C + GE W
Sbjct: 3134 NVCVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPCAEGEPTWSPWTPWS 3193
Query: 2334 FCPLQC-PAHSH-YELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQ 2391
C C PA H + C S P + PS AP + C +G + C+ G
Sbjct: 3194 QCSASCGPARCHRHRFCARS-PSAVPSTVAPLPLPATPTPLC---SGPEAEEEPCLLQG- 3248
Query: 2392 CGCLHDGRYYPLGEVFYPGPECERRCECGPGGHV-TCQEGAACGPHEECRLEDGVQA--- 2447
C G + P G P C R C G C + G + C +G +A
Sbjct: 3249 --CDRAGGWGPWG----PWSHCSRSCGGGLRSRTRACDQPPPQGLGDYC---EGPRAQGE 3299
Query: 2448 -CHATGCG--RCLANGGIHYITLDG---RVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEK 2501
C A C C A G Y R D C + C+ PG VL
Sbjct: 3300 VCQALPCPVTNCTAIEGAEYSPCGPPCPRSCDDLVHCVWRCQPGCYCPPGQ-----VLSS 3354
Query: 2502 NAAGDLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLR 2561
N A +Q + + L GQ+ G +A P EGR L T
Sbjct: 3355 NGAICVQPGHCSC----LDLLTGQRHH-PGARLARPDGCNHC-TCLEGR---LNCT---- 3401
Query: 2562 LLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSS 2621
+P P G C WS+ + + + + A P
Sbjct: 3402 -----------DLPCPVPGGWCP--------WSE-WTMCSQPCRGQTRSRSRACACPTPQ 3441
Query: 2622 KGCGEGCGPQGCPVCLAEETAPYESNEACGQLRN--------PQGPFATCQAVLSPSEYF 2673
G G G E EAC P GP++ C L S
Sbjct: 3442 HGGAPCTGEAG-------EAGAQHQREACPSYATCPVDGAWGPWGPWSPCDMCLGQSHRS 3494
Query: 2674 RQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRT 2733
R C + G C +P + +S C C +
Sbjct: 3495 RACSRPPTPEGG-------------RPCPGNHTQSRPCQENSTQCTDCGGGQSLHPCGQP 3541
Query: 2734 CQGSCAALSGLTGC---TTRCFEGCECDDRFLLSQGVCIPVQDCGCTH--NGRYLPVNSS 2788
C SC LS + C + C C C L G+C+P C C + +P N S
Sbjct: 3542 CPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRCQYQPGAMGIPENQS 3601
Query: 2789 -----------------LLTSDCSERCSCSSSSGLTCQ-AAGCP-PG 2816
++T C + C+C + L CQ CP PG
Sbjct: 3602 RSAGSRFSSWESLEPGEVVTGPC-DNCTCVAGI-LQCQEVPDCPDPG 3646
Score = 44.3 bits (103), Expect = 0.002
Identities = 41/121 (33%), Positives = 53/121 (43%), Gaps = 19/121 (15%)
Query: 1940 EDWRAQVGCEI-TCPENSHYEV-----CGPPCPASCPSPAPLTTPAVC-EGPCVEGCQCD 1992
E W AQ C CPE + C CP SC A L C +GPC GC+C
Sbjct: 4652 EPW-AQESCNGGPCPECEAQDTVFTLDCANQCPHSC---ADLWDRVQCLQGPCRPGCRCP 4707
Query: 1993 AGFVLSADRCVPLNNGCGCW---ANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPAS 2049
G ++ RCVP+++ C C AN ++ A ++ A Q C C SLVC
Sbjct: 4708 PGQLVQDGRCVPISS-CRCGLPSANASWELAPAQ--AVQLDCQNCTC--VNESLVCPHQE 4762
Query: 2050 C 2050
C
Sbjct: 4763 C 4763
Score = 43.9 bits (102), Expect = 0.002
Identities = 52/200 (26%), Positives = 68/200 (34%), Gaps = 48/200 (24%)
Query: 1428 CLPPTPCPPG--SED--CIPSHKCP----------PELEKKYQKEEFCGLLSSP-----T 1468
C P CP G S+D C+P C PE + + F S T
Sbjct: 3562 CQPTCGCPLGQLSQDGLCVPPAHCRCQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVT 3621
Query: 1469 GPLSSCHKLV------------DPQ-----GPLKDCIFDLCLGGGNL-SILCSNIHAYVS 1510
GP +C + DP GP +DC C GG L S C+
Sbjct: 3622 GPCDNCTCVAGILQCQEVPDCPDPGVWSSWGPWEDCSVS-CGGGEQLRSRRCAR-----P 3675
Query: 1511 ACQAAGGHVEPWRTETFCPMECPPNSHYELC--ADTCSLGCSALSAPPQC-QDGCAEGCQ 1567
C T+ CP Y C + C C+ ++ C +GC EGC
Sbjct: 3676 PCPGPARQSRTCSTQVCREAGCPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCH 3735
Query: 1568 CDSGFLYNGQACVPIQQCGC 1587
C G + ACV Q+C C
Sbjct: 3736 CPEGTFQHRLACV--QECPC 3753
Score = 43.1 bits (100), Expect = 0.004
Identities = 33/133 (24%), Positives = 46/133 (34%), Gaps = 10/133 (7%)
Query: 1103 GPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSY------GCPLSCGDL 1156
G C +LA C + ++ C CP + + + CP C
Sbjct: 2854 GRSCSSLAPGDTTCPGPHSQTRDCNTQP-CTAQCPENMLFRSAEQCHQEGGPCPRLCLTQ 2912
Query: 1157 PVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHC 1216
C C GC C G L SCLP + C C G + G C++ C C
Sbjct: 2913 GPGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYASG-AMARLDSCNN-CTC 2970
Query: 1217 QEGGLVSCESSSC 1229
G + +C S C
Sbjct: 2971 VSGKM-ACTSERC 2982
Score = 42.7 bits (99), Expect = 0.005
Identities = 29/105 (27%), Positives = 37/105 (35%), Gaps = 14/105 (13%)
Query: 714 LCRGLSAYAQACLELGISVGDWRSPANCPLS------------CPANSRYELCGPACPTS 761
+C G S ++AC G P N S C CG CP S
Sbjct: 3486 MCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTDCGGGQSLHPCGQPCPRS 3545
Query: 762 CNGAAAPSNCSGRP--CVEGCVCLPGFVASGGACVPASSCGCTFQ 804
C + S C C C C G ++ G CVP + C C +Q
Sbjct: 3546 CQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRCQYQ 3590
Score = 42.7 bits (99), Expect = 0.005
Identities = 58/252 (23%), Positives = 84/252 (33%), Gaps = 63/252 (25%)
Query: 2220 PADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLA 2279
P + ++ G + + W+ + GE V+ PC + CT G++ + P
Sbjct: 3597 PENQSRSAGSRFSSWE---SLEPGEVVTGPCDN-CTC----------VAGILQCQEVPDC 3642
Query: 2280 PCHGLVPPAQYFQGCLLDA----------CQVQGHPGGLCPAVATYVAACQAAGAQLGEW 2329
P G+ ++ C + C PG + C+ AG
Sbjct: 3643 PDPGVWSSWGPWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCSTQVCREAG------ 3696
Query: 2330 RRPDFCPLQCPAHSHYELC--GDSCPVSCPSLSAPEGCES-ACREGCVCDAGFVLSGDTC 2386
CPA Y C G+ CP SC ++ GC S C EGC C G C
Sbjct: 3697 ---------CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLAC 3747
Query: 2387 VPVGQC----------GCLHDGRYYPLGEVFYPGPECER----RCECGPGGHVTCQEGAA 2432
V C G PLG PG E + R C G+ +C G
Sbjct: 3748 VQECPCVLTAWLLQELGATIGDPGQPLG----PGDELDSGQTLRTSC---GNCSCAHGKL 3800
Query: 2433 CGPHEECRLEDG 2444
++C DG
Sbjct: 3801 SCSLDDCFEADG 3812
Score = 42.0 bits (97), Expect = 0.009
Identities = 25/84 (29%), Positives = 31/84 (36%), Gaps = 6/84 (7%)
Query: 1114 AACQAAGATVHPWRSEELCPLSCPPHSHYEA-----CSYGCPLSCGDLPVPGGC-GSECH 1167
A G PW E CP + C+ CP SC DL C C
Sbjct: 4642 AEALCGGGCREPWAQESCNGGPCPECEAQDTVFTLDCANQCPHSCADLWDRVQCLQGPCR 4701
Query: 1168 EGCVCDEGFALSGESCLPLASCGC 1191
GC C G + C+P++SC C
Sbjct: 4702 PGCRCPPGQLVQDGRCVPISSCRC 4725
Score = 41.6 bits (96), Expect = 0.012
Identities = 73/320 (22%), Positives = 95/320 (29%), Gaps = 94/320 (29%)
Query: 1018 GGGQAANALAFGNSWQEETRPG---CGATEPGDCPKLDSLVAQQLQSKNECGILADPKGP 1074
GGG S E + G C PG CP+ D Q C L+ P+G
Sbjct: 3057 GGGYRNRTRGSSRSLMEFSTCGLQPCAGPVPGMCPR-DKQWLDCAQGPASCAELSAPRGT 3115
Query: 1075 FRECHSKLD-PQGAVR-----------DCVYDRCLLPGQSGPL-----CDALATYAAACQ 1117
+ CH P G + C ++ L P S + C ++ A C
Sbjct: 3116 NQTCHPGCHCPSGMLLLNNVCVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCS 3175
Query: 1118 A-----AGATVHPWRSEELCPLSCPP-----HSHYEACSYGCPLSCGDLPVP-------- 1159
+ T PW C SC P H P + LP+P
Sbjct: 3176 SWPCAEGEPTWSPWTPWSQCSASCGPARCHRHRFCARSPSAVPSTVAPLPLPATPTPLCS 3235
Query: 1160 -----------------GGCG-----SECHEGC---------VCD-----------EGFA 1177
GG G S C C CD EG
Sbjct: 3236 GPEAEEEPCLLQGCDRAGGWGPWGPWSHCSRSCGGGLRSRTRACDQPPPQGLGDYCEGPR 3295
Query: 1178 LSGESC----LPLASCGCVHQGTYHPPGQTFYPGP-GCDSLCHCQEGGLVSCESSSCGPH 1232
GE C P+ +C + Y P G P P CD L HC + C+ P
Sbjct: 3296 AQGEVCQALPCPVTNCTAIEGAEYSPCGP---PCPRSCDDLVHC----VWRCQPGCYCPP 3348
Query: 1233 EACQPSGGSLGCVAVGSSTC 1252
S G++ CV G +C
Sbjct: 3349 GQVLSSNGAI-CVQPGHCSC 3367
Score = 41.6 bits (96), Expect = 0.012
Identities = 38/140 (27%), Positives = 53/140 (37%), Gaps = 28/140 (20%)
Query: 2723 AHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQ-GVCIPVQDCGCTHNGR 2781
A +C +TC A + C++ GC C SQ G C+P C C H GR
Sbjct: 4933 APGELGLCEQTCL-EMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDHCECWHLGR 4991
Query: 2782 -YLP-------VNSSLLTSD---CSERCS---CSSSSGLTCQAAGCPP----------GR 2817
+LP S L S C++ CS C+ + + C P
Sbjct: 4992 PHLPGSEWQEACESCLCLSGRPVCTQHCSPLTCAQGEEMVLEPGSCCPSCRREAPEEQSP 5051
Query: 2818 VCEVKAEARNCWATRGLCVL 2837
C++ E RN T+G C L
Sbjct: 5052 SCQLLTELRN--FTKGTCYL 5069
Score = 41.2 bits (95), Expect = 0.016
Identities = 37/132 (28%), Positives = 45/132 (34%), Gaps = 28/132 (21%)
Query: 1952 CPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGC 2011
CP + + C PASC A L+ P C GC C +G +L + CVP + C C
Sbjct: 3090 CPRDKQWLDCAQG-PASC---AELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQD-CPC 3144
Query: 2012 WANGTYHEAGSEFWAD-----------GTCSQWCRCGPGGG-----------SLVCTPAS 2049
G + GS CS W C G S C PA
Sbjct: 3145 AHEGHLYPPGSTVVRPCENCSCVSGLIANCSSW-PCAEGEPTWSPWTPWSQCSASCGPAR 3203
Query: 2050 CGLGEVCGLLPS 2061
C C PS
Sbjct: 3204 CHRHRFCARSPS 3215
Score = 41.2 bits (95), Expect = 0.016
Identities = 34/111 (30%), Positives = 43/111 (38%), Gaps = 12/111 (10%)
Query: 2717 CPL-HCPA--HSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQ--GVCIPV 2771
CP+ +C A + YS C C SC L C RC GC C +LS +C+
Sbjct: 3306 CPVTNCTAIEGAEYSPCGPPCPRSC---DDLVHCVWRCQPGCYCPPGQVLSSNGAICVQP 3362
Query: 2772 QDCGCTH--NGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCP-PGRVC 2819
C C G+ + L D C+C L C CP PG C
Sbjct: 3363 GHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGR-LNCTDLPCPVPGGWC 3412
Score = 40.8 bits (94), Expect = 0.020
Identities = 172/773 (22%), Positives = 231/773 (29%), Gaps = 192/773 (24%)
Query: 1422 VVPDSP--CLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTG--PLSSCHKL 1477
+VP P CL P S C+ +CPP GLL T PLS C L
Sbjct: 2631 LVPPCPPSCLDPKANRSCSGHCVEGCRCPP------------GLLLHDTRCLPLSECPCL 2678
Query: 1478 VDPQGPLKDCIFDLCLGGGNLS-ILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPN- 1535
V + F L GN S +C CQ G CP+ C +
Sbjct: 2679 VGEELKWPGVSFLL----GNCSQCVCEKGELL---CQPGG-----------CPLPCGWSA 2720
Query: 1536 -SHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYY 1594
S + C +C G A P G C+ G Q C + CG G +
Sbjct: 2721 WSSWAPCDRSCGSGVRARFRSPSNPPAAWGGAPCE-GDRQELQGCHTV--CGTEVFG--W 2775
Query: 1595 EPEQTVLIDNCRQQCTCHAG-KGMVCQEHSCKPGQVCQPSGGILSC----VTKDPCHGVT 1649
P + +C Q C G G + C PS G SC ++PC
Sbjct: 2776 TPWTSW--SSCSQSCLAPGGGPGWRSRSRLC-------PSPGDSSCPGDATQEEPCSPPV 2826
Query: 1650 C---------RPQETCKEQGGQGVCLPNYEATCWLWGD-----PHYHSFDGRK------- 1688
C P TC G+ + GD PH + D
Sbjct: 2827 CPVPSIWGLWAPWSTCSAPCDGGIQTRGRSCSSLAPGDTTCPGPHSQTRDCNTQPCTAQC 2886
Query: 1689 ------------FDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVT 1736
G C + T G PG+ G T + A R
Sbjct: 2887 PENMLFRSAEQCHQEGGPCPRLCLTQG-PGIECTGFCAPGCTCPPGLFLHNASCLPRSQC 2945
Query: 1737 VAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALL--VADFGLQVS 1794
L + + ++ C N + ++ R VA G S L + V
Sbjct: 2946 PCQLHGQLYA-SGAMARLDSCNNCTCVSGKMACTSERCPVACGWSPWTLWSLCSCSCNVG 3004
Query: 1795 YDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVF--------PNGTLAP----SIPIW 1842
+R P+++ GA C + P + F P G P S+P
Sbjct: 3005 IRRRFRAGTAPPAAFGGAEC-------QGPTMEAEFCSLRPCPGPGGEWGPWSPCSVPCG 3057
Query: 1843 GG--------SWRAPGWDPLCWDECRGSCP-TCPEDR--LEQYEGPGFCGPLASGTGGPF 1891
GG S + C G P CP D+ L+ +GP C L S G
Sbjct: 3058 GGYRNRTRGSSRSLMEFSTCGLQPCAGPVPGMCPRDKQWLDCAQGPASCAEL-SAPRGTN 3116
Query: 1892 TTCH--AHVPPESFFKGCVL--DVCMGGGDRDIL------------------CKALASYV 1929
TCH H P G +L +VC+ D C ++ +
Sbjct: 3117 QTCHPGCHCP-----SGMLLLNNVCVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLI 3171
Query: 1930 AACQA-----AGVVIEDWRAQVGCEITC-PENSHYEVCGPPCPASCPS-----PAPLTTP 1978
A C + W C +C P H P++ PS P P T
Sbjct: 3172 ANCSSWPCAEGEPTWSPWTPWSQCSASCGPARCHRHRFCARSPSAVPSTVAPLPLPATPT 3231
Query: 1979 AVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGP 2038
+C GP E C + DR G G W ++ CS+ C G
Sbjct: 3232 PLCSGPEAEEEPC---LLQGCDRA----GGWGPWGPWSH------------CSRSCGGGL 3272
Query: 2039 GGGSLVCT-PASCGLG----------EVCGLLPSGQHGCQPVSTAECQAWGDP 2080
+ C P GLG EVC LP C + AE G P
Sbjct: 3273 RSRTRACDQPPPQGLGDYCEGPRAQGEVCQALPCPVTNCTAIEGAEYSPCGPP 3325
Score = 40.4 bits (93), Expect = 0.027
Identities = 53/203 (26%), Positives = 66/203 (32%), Gaps = 50/203 (24%)
Query: 1071 PKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEE 1130
P GP+ C L R C R P + G C T + CQ +
Sbjct: 3477 PWGPWSPCDMCLGQSHRSRAC--SRPPTP-EGGRPCPGNHTQSRPCQ---------ENST 3524
Query: 1131 LCPLSCPPHSHYEACSYGCPLSCGDLPV-----PGGCGSECHEGCVCDEGFALSGESCLP 1185
C C C CP SC DL PG G C C C G C+P
Sbjct: 3525 QCT-DCGGGQSLHPCGQPCPRSCQDLSPGSVCQPGSVG--CQPTCGCPLGQLSQDGLCVP 3581
Query: 1186 LASCGCVHQ--------------GTYHPPGQTFYPGP----GCDSLCHCQEGGLVSCES- 1226
A C C +Q G+ ++ PG CD+ C C G++ C+
Sbjct: 3582 PAHCRCQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDN-CTC-VAGILQCQEV 3639
Query: 1227 ---------SSCGPHEACQPSGG 1240
SS GP E C S G
Sbjct: 3640 PDCPDPGVWSSWGPWEDCSVSCG 3662
Score = 40.0 bits (92), Expect = 0.035
Identities = 60/231 (25%), Positives = 79/231 (34%), Gaps = 52/231 (22%)
Query: 2234 WQVGGAQGC---GECVSKPCPSPCTPEQQESFGGPDACGVIS--ATDGPLA----PCHGL 2284
W G ++ C G V + CP P E Q AC V +T P + PC G
Sbjct: 1713 WGQGRSRRCSPLGLLVLQNCPGP---EHQSQACFTAACPVDGEWSTWSPWSVCSEPCRGT 1769
Query: 2285 VPPAQYFQGCLLDACQVQGHPGGL--------CPAVATYVAACQAAGAQLGEWRRPDFCP 2336
+ + PGGL CP A C +G + + P CP
Sbjct: 1770 MTRQRQCHSPQNGGRTCAALPGGLHSTRQTKPCPQDGCPNATC--SGELMFQPCAP--CP 1825
Query: 2337 LQCPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGD-TCVPVGQCGCL 2395
L C S C P P GC C G VL + CV QC CL
Sbjct: 1826 LTCDDISGQVTCPPDWPCGSP--------------GCWCPEGQVLGSEGWCVWPRQCPCL 1871
Query: 2396 HDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEG--AACGPHEECRLEDG 2444
DG Y +PG + C+ CQ+G C + +C ++ G
Sbjct: 1872 VDGARY------WPGQRIKADCQL-----CICQDGRPRRCRLNPDCAVDCG 1911
Score = 40.0 bits (92), Expect = 0.035
Identities = 30/100 (30%), Positives = 34/100 (34%), Gaps = 10/100 (10%)
Query: 2721 CPAHSHYSICTRTCQGSCAALSGLTGCTTR--CFEGCECDDRFLLSQGVCIPVQDCGCTH 2778
C + C C G CA C C GC C L G CIP ++C C H
Sbjct: 4423 CTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIPPEECNCWH 4482
Query: 2779 N-----GRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGC 2813
G L L C E C C L C + GC
Sbjct: 4483 TSAAGAGMTLAPGDRLQLG-CKE-CECRRGE-LHCTSQGC 4519
Score = 39.7 bits (91), Expect = 0.045
Identities = 62/253 (24%), Positives = 81/253 (32%), Gaps = 54/253 (21%)
Query: 1833 GTLAPSIPIWG-GSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLA----SGT 1887
G + PS G G+W W P W C +C + R + C PL
Sbjct: 1683 GQVGPSPEEQGCGAWGP--WSP--WGPCSRTCGPWGQGRSRR------CSPLGLLVLQNC 1732
Query: 1888 GGPFTTCHAHVPPESFFKGCVLD--------------VCMGGGDRDILCKALASYVAACQ 1933
GP H F C +D C G R C + + C
Sbjct: 1733 PGP-----EHQSQACFTAACPVDGEWSTWSPWSVCSEPCRGTMTRQRQCHSPQNGGRTCA 1787
Query: 1934 AAGVVIEDWRA-----QVGC-EITCPENSHYEVCGPPCPASCPS-PAPLTTPAVCEGPCV 1986
A + R Q GC TC ++ C P CP +C +T P + PC
Sbjct: 1788 ALPGGLHSTRQTKPCPQDGCPNATCSGELMFQPCAP-CPLTCDDISGQVTCPP--DWPCG 1844
Query: 1987 E-GCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVC 2045
GC C G VL ++ C C +G + G AD Q C C G
Sbjct: 1845 SPGCWCPEGQVLGSEGWCVWPRQCPCLVDGARYWPGQRIKAD---CQLCICQDG------ 1895
Query: 2046 TPASCGLGEVCGL 2058
P C L C +
Sbjct: 1896 RPRRCRLNPDCAV 1908
Score = 38.9 bits (89), Expect = 0.078
Identities = 29/101 (28%), Positives = 33/101 (32%), Gaps = 15/101 (14%)
Query: 1145 CSYGCPLSCGDLPVPGGCGSECHEGCVCDEG-FALSGESCLPLASCGCVHQGTYHPPGQT 1203
C C L C S GCVC G F C+P C C H G H PG
Sbjct: 4940 CEQTC-LEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDHCECWHLGRPHLPGSE 4998
Query: 1204 FYPG----------PGCDSLCH---CQEGGLVSCESSSCGP 1231
+ P C C C +G + E SC P
Sbjct: 4999 WQEACESCLCLSGRPVCTQHCSPLTCAQGEEMVLEPGSCCP 5039
Score = 37.4 bits (85), Expect = 0.23
Identities = 33/124 (26%), Positives = 44/124 (35%), Gaps = 27/124 (21%)
Query: 2658 GPFATCQAVLSPSEYFR--QCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDS 2715
GP+ C E R +C C ++ C T C+ AG
Sbjct: 3652 GPWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCS-----TQVCREAG---------- 3696
Query: 2716 FCPLHCPAHSHYSICT--RTCQGSCAALSGLTGCTTR-CFEGCECDDRFLLSQGVCIPVQ 2772
CPA Y C C SCA ++ GC + C EGC C + + C VQ
Sbjct: 3697 -----CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLAC--VQ 3749
Query: 2773 DCGC 2776
+C C
Sbjct: 3750 ECPC 3753
Score = 34.3 bits (77), Expect = 1.9
Identities = 35/150 (23%), Positives = 45/150 (30%), Gaps = 33/150 (22%)
Query: 1860 RGSCP---TCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDVCMGGG 1916
R +CP TCP D A G GP++ C D+C+G
Sbjct: 3460 REACPSYATCPVDG-------------AWGPWGPWSPC---------------DMCLGQS 3491
Query: 1917 DRDILCKALASYVAACQAAGVVIEDWRAQVGCE--ITCPENSHYEVCGPPCPASCPSPAP 1974
R C + G + Q C CG PCP SC +P
Sbjct: 3492 HRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTDCGGGQSLHPCGQPCPRSCQDLSP 3551
Query: 1975 LTTPAVCEGPCVEGCQCDAGFVLSADRCVP 2004
+ C C C G + CVP
Sbjct: 3552 GSVCQPGSVGCQPTCGCPLGQLSQDGLCVP 3581
Score = 32.7 bits (73), Expect = 5.6
Identities = 39/143 (27%), Positives = 47/143 (32%), Gaps = 26/143 (18%)
Query: 1865 TCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKA 1924
TC L+ E P P + GP+ C V GGG++ ++
Sbjct: 3628 TCVAGILQCQEVPDCPDPGVWSSWGPWEDC---------------SVSCGGGEQ---LRS 3669
Query: 1925 LASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPP--CPASCPSPAPLTTPAVC- 1981
C QV E CP Y C P CP SC A +T C
Sbjct: 3670 RRCARPPCPGPARQSRTCSTQVCREAGCPAGRLYRECQPGEGCPFSC---AHVTQQVGCF 3726
Query: 1982 -EGPCVEGCQCDAGFVLSADRCV 2003
EG C EGC C G CV
Sbjct: 3727 SEG-CEEGCHCPEGTFQHRLACV 3748
Score = 32.3 bits (72), Expect = 7.3
Identities = 30/99 (30%), Positives = 37/99 (37%), Gaps = 13/99 (13%)
Query: 1157 PVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHC 1216
P P G G +C G C GC HQG H G+ ++ GP C +C C
Sbjct: 1940 PRPSGRGRQCR-------GIHRKARRCQTEPCEGCEHQGQVHRVGERWHGGP-C-RVCQC 1990
Query: 1217 QEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQAS 1255
C S C P +C P G L G S C +
Sbjct: 1991 LHNLTAHC-SPYC-PLGSC-PQGWVL-VEGTGESCCHCA 2025
>gi|161019170 mucin 5AC [Homo sapiens]
Length = 6207
Score = 400 bits (1029), Expect = e-111
Identities = 380/1407 (27%), Positives = 553/1407 (39%), Gaps = 278/1407 (19%)
Query: 466 AESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRGSRRV 525
A + VC GD HY TFDG + G C+Y E C F+V+ + GSR V
Sbjct: 727 AHNGRVCSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCRA--AYEDFNVQLRRGLVGSRPV 784
Query: 526 SYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGL 585
V V ++A + + G V L++ QR LP S + L V QSG +++ L
Sbjct: 785 --VTRVVIKAQGLVLEASNGSV---LINGQREELPYSRTG--LLVEQSGD--YIKVSIRL 835
Query: 586 VVTYDWDCQ--LALSLPARFQDQVCGLCGNYNGDPA-DDFLTPDGALAPDAVEFASSWKL 642
V+T+ W+ + L L ++ +Q CGLCG++NG PA ++F + L P ++F + KL
Sbjct: 836 VLTFLWNGEDSALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLTP--LQFGNLQKL 893
Query: 643 DDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVY 702
D C D CT + + +C T L FA CH +D +L C
Sbjct: 894 DGPTEQCPDPLPLPAGNCT-------DEEGICHR-TLLGPAFAECHALVDSTAYLAACAQ 945
Query: 703 DLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSC 762
DLC C Y++ C G +WR P CP +CP N +++ CG C +C
Sbjct: 946 DLCRCP---TCPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTC 1002
Query: 763 NGAAAPSNCSGRPCVEGCVCLPGFVA------SGGACVPASSCGCTFQGLQLAPGQEVWA 816
+ C CV+GC C PG + C+P C CT G +PG
Sbjct: 1003 SNPQRAQLCEDH-CVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHGGRTYSPGTSF-- 1059
Query: 817 DELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFD 876
+ C CTC+G Q C+D CP GTC G H ++D
Sbjct: 1060 NTTCS-SCTCSGGLWQ--CQD-LPCP-------------------GTCSVQGGAHISTYD 1096
Query: 877 GRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRG-SQTVSYTRAVRVEARGVKVAVR 935
+ +D G C+Y+L C + +F VL E G + + +AV + G A+R
Sbjct: 1097 EKLYDLHGDCSYVLSKKCADS----SFTVLAELRKCGLTDNENCLKAVTLSLDGGDTAIR 1152
Query: 936 REYPGQVLVDDVLQYLPFQAADGQVQVFRQGR-DAVVRTDFGLTVTYDW--NARVTAKVP 992
+ G V ++ + LP AA+ + +F VV+T GL + +V ++
Sbjct: 1153 VQADGGVFLNSIYTQLPLSAAN--ITLFTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLD 1210
Query: 993 SSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPKLD 1052
++ +CGLCGNFN + ADD G A AF N+W+ + C
Sbjct: 1211 PAHQGQMCGLCGNFNQNQADDFTALSGVVEATGAAFANTWKAQA--ACANARNSFEDPCS 1268
Query: 1053 SLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATY 1112
V + +++ C L DP F CHS ++P+ +C++D C LC AL++Y
Sbjct: 1269 LSVENENYARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNCERSEDCLCAALSSY 1328
Query: 1113 AAACQAAGATVHPWRSEELCP---LSCPPHSHYEACSYGCPLSC---GDLPVPGGCGSEC 1166
AC A G + WR + +C +CP Y C +C + V
Sbjct: 1329 VHACAAKGVQLSDWR-DGVCTKYMQNCPKSQRYAYVVDACQPTCRGLSEADVTCSVSFVP 1387
Query: 1167 HEGCVCDEG-FALSGESCLPLASCGCVHQGTYHPPGQTFY-------------------- 1205
+GC C G F +C+P C C GT PG+ +
Sbjct: 1388 VDGCTCPAGTFLNDAGACVPAQECPCYAHGTVLAPGEVVHDEGAVCSCTGGKLSCLGASL 1447
Query: 1206 ----------------------PGPGCDSLCHCQEGGLVSCESSSCGPHEACQP---SGG 1240
PG C CH + V C S+ C C P S G
Sbjct: 1448 QKSTGCAAPMVYLDCSNSSAGTPGAECLRSCHTLD---VGCFSTHCVSGCVCPPGLVSDG 1504
Query: 1241 SLGCVA--------------------VGSSTCQ------------------ASGDPHYTT 1262
S GC+A V +TC A GD H+ T
Sbjct: 1505 SGGCIAEEDCPCVHNEATYKPGETIRVDCNTCTCRNRRWECSHRLCLGTCVAYGDGHFIT 1564
Query: 1263 FDGRRFDFMGTCVYVLAQT-CGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLR 1321
FDG R+ F G+C Y+LAQ CG F ++ EN+ G + ++ I + V T
Sbjct: 1565 FDGDRYSFEGSCEYILAQDYCGDNTTHGTFRIVTENIPCGTTGTTCSKAIKLFVEVRTAP 1624
Query: 1322 L---------EQRQWKVTVNGVDMKLP------VVLANGQIRASQHGSD----------- 1355
E + +V G +LP ++L G +A G
Sbjct: 1625 AVSTPDPAANEPAPREASV-GFRQRLPPLQSYELILQEGTFKAVARGPGGDPPYKIRYMG 1683
Query: 1356 --VVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNAN 1413
+VIET G+ V++D V + + +Y ++CGLCGN++ + +DF + S G+A
Sbjct: 1684 IFLVIET-HGMAVSWDRKTSVFIRLHQDYKGRVCGLCGNFDDNAINDFATRSRSVVGDAL 1742
Query: 1414 EFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSS 1473
EFGNSW+ L P+ CP + P C +K ++ C +L PT ++
Sbjct: 1743 EFGNSWK--------LSPS-CP---DALAPKDPCTANPFRKSWAQKQCSILHGPT--FAA 1788
Query: 1474 CHKLVDPQGPLKDCIFDLCL--GGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPME 1531
C VD + C+ D C GG+ C+ + AY AC AG V WRT CP+
Sbjct: 1789 CRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACHDAGLCVS-WRTPDTCPLF 1847
Query: 1532 CP---PNS----HYELCADTCSLGCSALSAPPQC------QDGCAEGCQCDSGFLYNGQA 1578
C P+ HY+ C C C S C +GC C F +N
Sbjct: 1848 CDFYNPHGGCEWHYQPCGAPCLKTCRNPSG--HCLVDLPGLEGCYPKCPPSQPF-FNEDQ 1904
Query: 1579 CVPIQQCGCY-HNGVYYEPEQTV-LIDNCRQQCTCHAGKGMVCQEHSCKPGQVCQPSGGI 1636
+ QCGCY +G YY+ V +NC Q C C PSG
Sbjct: 1905 MKCVAQCGCYDKDGNYYDVGARVPTAENC-QSCN-------------------CTPSG-- 1942
Query: 1637 LSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTC- 1695
+ C H + C YE + + D Y++ DG C
Sbjct: 1943 IQC-----AHSLE--------------ACTCTYEDRTYSYQDVIYNTTDGLGACLIAICG 1983
Query: 1696 ---NYVLATTGCPGVSTQGLTPFTVTT 1719
+ CPG T TPFT TT
Sbjct: 1984 SNGTIIRKAVACPG--TPATTPFTFTT 2008
Score = 344 bits (882), Expect = 9e-94
Identities = 340/1347 (25%), Positives = 486/1347 (36%), Gaps = 244/1347 (18%)
Query: 1673 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYV 1732
C WGD HY +FDG F F G CNYV + F V + G+ V V
Sbjct: 733 CSTWGDFHYKTFDGDVFRFPGLCNYVFSEH-----CRAAYEDFNVQLRRGLVGSRPV--V 785
Query: 1733 RVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVADFGLQ 1792
V + A G + E V +NG LP S R + S + L
Sbjct: 786 TRVVIKAQGLVL-----EASNGSVLINGQREELPYS----RTGLLVEQSGDYIKVSIRLV 836
Query: 1793 VSYDWNWRVD--VTLPSSYHGAVCGLCGNMDRNPNNDQVFP-NGTLAPSIPIWGGSWRAP 1849
+++ WN + L Y CGLCG+ + P ++ + N L P +G +
Sbjct: 837 LTFLWNGEDSALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLTPLQ--FGNLQKLD 894
Query: 1850 GWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVL 1909
G C D C ++ G C G F CHA V ++ C
Sbjct: 895 GPTEQCPDPLPLPAGNCTDEE-------GICHRTLLGPA--FAECHALVDSTAYLAACAQ 945
Query: 1910 DVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASC 1969
D+C C Y C AG +WR C TCP N ++ CG PC +C
Sbjct: 946 DLCRCP---TCPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTC 1002
Query: 1970 PSPAPLTTPAVCEGPCVEGCQCDAGFV------LSADRCVPLNNGCGCWANGTYHEAGSE 2023
+P +CE CV+GC C G ++ C+PL C C G + G+
Sbjct: 1003 SNP---QRAQLCEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQ-CPCTHGGRTYSPGTS 1058
Query: 2024 FWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYV 2083
F + TCS C C GG C C C G H
Sbjct: 1059 F--NTTCSS-CTC--SGGLWQCQDLPC--------------------PGTCSVQGGAHIS 1093
Query: 2084 TLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTLQIYNHS 2142
T D +D G C Y+LS C +FTV G + + ++VTL +
Sbjct: 1094 TYDEKLYDLHGDCSYVLSKKC-----ADSSFTVLAELRKCGLTDNENCLKAVTLSLDGGD 1148
Query: 2143 LTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVR--LR 2200
+ + + ++ ++ LP ++ S +VV T GL L ++ +R
Sbjct: 1149 TAIRVQADGGVFLNSIYTQLPLSAANITLFTPSSFFIVVQTGLGLQLLVQLVPLMQVFVR 1208
Query: 2201 VPAAYAASLCGLCGNYNQDPADDLKAVGG-----KPAGWQVGGAQGCGECVSKPCPSPCT 2255
+ A+ +CGLCGN+NQ+ ADD A+ G A AQ PC+
Sbjct: 1209 LDPAHQGQMCGLCGNFNQNQADDFTALSGVVEATGAAFANTWKAQAACANARNSFEDPCS 1268
Query: 2256 PEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATY 2315
+ C ++ + + CH ++ P + C+ D C + LC A+++Y
Sbjct: 1269 LSVENENYARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNCERSEDCLCAALSSY 1328
Query: 2316 VAACQAAGAQLGEWRRPDFCP---LQCPAHSHYELCGDSCPVSCPSLSAPEGCESAC--- 2369
V AC A G QL +W R C CP Y D+C +C LS + S
Sbjct: 1329 VHACAAKGVQLSDW-RDGVCTKYMQNCPKSQRYAYVVDACQPTCRGLSEADVTCSVSFVP 1387
Query: 2370 REGCVCDAG-FVLSGDTCVPVGQCGCLHDGRYYPLGEVFY-------------------- 2408
+GC C AG F+ CVP +C C G GEV +
Sbjct: 1388 VDGCTCPAGTFLNDAGACVPAQECPCYAHGTVLAPGEVVHDEGAVCSCTGGKLSCLGASL 1447
Query: 2409 ----------------------PGPECERRCE----------------CGPG------GH 2424
PG EC R C C PG G
Sbjct: 1448 QKSTGCAAPMVYLDCSNSSAGTPGAECLRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGG 1507
Query: 2425 VTCQEGAAC-------GPHEECRLEDGVQAC--------HATGCGRCLANGGIHYITLDG 2469
+E C P E R++ C H G C+A G H+IT DG
Sbjct: 1508 CIAEEDCPCVHNEATYKPGETIRVDCNTCTCRNRRWECSHRLCLGTCVAYGDGHFITFDG 1567
Query: 2470 RVYDLHGSCSYVLAQ-VCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVSLAQGQQVT 2528
Y GSC Y+LAQ C F IV E G V + V+
Sbjct: 1568 DRYSFEGSCEYILAQDYCGDNTTHGTFRIVTENIPCGTTGTTCSKAIKLFVEVRTAPAVS 1627
Query: 2529 VDGEAVALP----------------------VAVGRVRVTAEGRN------------MVL 2554
A P + G + A G ++
Sbjct: 1628 TPDPAANEPAPREASVGFRQRLPPLQSYELILQEGTFKAVARGPGGDPPYKIRYMGIFLV 1687
Query: 2555 QTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAA 2614
T G+ + +D + + + ++GR+CGLCGNF+ N +DF + S FG +
Sbjct: 1688 IETHGMAVSWDRKTSVFIRLHQDYKGRVCGLCGNFDDNAINDFATRSRSVVGDALEFGNS 1747
Query: 2615 WRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFR 2674
W+ S C + P+ C A + + C L P FA C++ + ++Y+
Sbjct: 1748 WKL---SPSCPDALAPK--DPCTANPFRKSWAQKQCSILHGP--TFAACRSQVDSTKYYE 1800
Query: 2675 QCVYDLCA--QKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHS------- 2725
CV D CA GD C ++AAY AC AG+ V WRT CPL C ++
Sbjct: 1801 ACVNDACACDSGGDCECFCTAVAAYAQACHDAGLCVS-WRTPDTCPLFCDFYNPHGGCEW 1859
Query: 2726 HYSICTRTCQGSC--------AALSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQDCGC- 2776
HY C C +C L GL GC +C F Q C V CGC
Sbjct: 1860 HYQPCGAPCLKTCRNPSGHCLVDLPGLEGCYPKC---PPSQPFFNEDQMKC--VAQCGCY 1914
Query: 2777 THNGRYLPVNSSLLTSDCSERCSCSSSSGLTC----QAAGCP-PGRVCEVKAEARNCWAT 2831
+G Y V + + T++ + C+C + SG+ C +A C R + N
Sbjct: 1915 DKDGNYYDVGARVPTAENCQSCNC-TPSGIQCAHSLEACTCTYEDRTYSYQDVIYNTTDG 1973
Query: 2832 RGLCVLSV-GANLTTFDGARGATTSPG 2857
G C++++ G+N T R A PG
Sbjct: 1974 LGACLIAICGSNGTII---RKAVACPG 1997
Score = 335 bits (858), Expect = 5e-91
Identities = 363/1378 (26%), Positives = 507/1378 (36%), Gaps = 289/1378 (20%)
Query: 1252 CQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVI 1311
C GD HY TFDG F F G C YV ++ C R A NV G V V+
Sbjct: 733 CSTWGDFHYKTFDGDVFRFPGLCNYVFSEHC-------RAAYEDFNVQLRRGLVGSRPVV 785
Query: 1312 T-VQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDL 1370
T V + L LE V +NG +LP + + Q G + + L ++
Sbjct: 786 TRVVIKAQGLVLEASNGSVLINGQREELPY--SRTGLLVEQSGDYIKVSIRLVLTFLWNG 843
Query: 1371 VYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNAN----EFGNSWEEVVPDS 1426
+ + Y Q CGLCG++NG P N A NA +FGN + P
Sbjct: 844 EDSALLELDPKYANQTCGLCGDFNGLPAF-----NEFYAHNARLTPLQFGNLQKLDGPTE 898
Query: 1427 PCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGP-LSSCHKLVDPQGPLK 1485
C P P P G+ C E E C + GP + CH LVD L
Sbjct: 899 QCPDPLPLPAGN--------CTDE-------EGICH--RTLLGPAFAECHALVDSTAYLA 941
Query: 1486 DCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTC 1545
C DLC + C+ Y C AGG WR CP CP N ++ C C
Sbjct: 942 ACAQDLCRCP---TCPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPC 998
Query: 1546 SLGCSALSAPPQCQDGCAEGCQCDSG--------FLYNGQACVPIQQCGCYHNGVYYEPE 1597
+ CS C+D C +GC C G ++G C+P+ QC C H G Y P
Sbjct: 999 TDTCSNPQRAQLCEDHCVDGCFCPPGRSCTVLDDITHSG--CLPLGQCPCTHGGRTYSPG 1056
Query: 1598 QTVLIDNCRQQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCK 1657
+ + CTC SGG+ C PC G TC
Sbjct: 1057 TS--FNTTCSSCTC---------------------SGGLWQCQDL-PCPG-------TCS 1085
Query: 1658 EQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTV 1717
QGG H ++D + +D G C+YVL+ C S FTV
Sbjct: 1086 VQGGA-----------------HISTYDEKLYDLHGDCSYVLSKK-CADSS------FTV 1121
Query: 1718 TTKNQNRG-NPAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISV 1776
+ + G + ++ VT++ G + +I G V +N + T LP+S A+ I++
Sbjct: 1122 LAELRKCGLTDNENCLKAVTLSLDGGDTAIRVQADGGV--FLNSIYTQLPLSAAN--ITL 1177
Query: 1777 AQGASKALLV-ADFGLQVSYDWN--WRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNG 1833
+S ++V GLQ+ +V V L ++ G +CGLCGN ++N +D +G
Sbjct: 1178 FTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLDPAHQGQMCGLCGNFNQNQADDFTALSG 1237
Query: 1834 TLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLASGTGGPFTT 1893
+ + + +W+A + C E+ E Y +C L F+
Sbjct: 1238 VVEATGAAFANTWKAQAACANARNSFEDPCSLSVEN--ENY-ARHWCSRLTDPNSA-FSR 1293
Query: 1894 CHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEI--T 1951
CH+ + P+ F C+ D C D LC AL+SYV AC A GV + DWR V +
Sbjct: 1294 CHSIINPKPFHSNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLSDWRDGVCTKYMQN 1353
Query: 1952 CPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAG-FVLSADRCVPLNNGCG 2010
CP++ Y C +C + V+GC C AG F+ A CVP C
Sbjct: 1354 CPKSQRYAYVVDACQPTCRGLSEADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQE-CP 1412
Query: 2011 CWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPAS--------------------- 2049
C+A+GT G +G C GG L C AS
Sbjct: 1413 CYAHGTVLAPGEVVHDEGAV-----CSCTGGKLSCLGASLQKSTGCAAPMVYLDCSNSSA 1467
Query: 2050 ----------------------CGLGEVC--GLLPSGQHGCQPVSTAEC----------- 2074
C G VC GL+ G GC C
Sbjct: 1468 GTPGAECLRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKPGE 1527
Query: 2075 -------------QAWGDPHYVTL--------------DGHRFDFQGTCEYLLSAPCHGP 2107
+ W H + L DG R+ F+G+CEY+L+ G
Sbjct: 1528 TIRVDCNTCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGD 1587
Query: 2108 PLGAENFTVTVANEHRGSQAVSYTRSVTL--------QIYNHSLTLSARWPRKLQVDGVF 2159
F + N G+ + ++++ L + + PR+ V
Sbjct: 1588 NTTHGTFRIVTENIPCGTTGTTCSKAIKLFVEVRTAPAVSTPDPAANEPAPREASVGFRQ 1647
Query: 2160 VALPFQLDSLL--------HAHLSGAD----------VVVTTTSGLSLAFDGDSFVRLRV 2201
P Q L+ A G D +V T G+++++D + V +R+
Sbjct: 1648 RLPPLQSYELILQEGTFKAVARGPGGDPPYKIRYMGIFLVIETHGMAVSWDRKTSVFIRL 1707
Query: 2202 PAAYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGEC--VSKPCP------SP 2253
Y +CGLCGN++ + +D VG A G +S CP P
Sbjct: 1708 HQDYKGRVCGLCGNFDDNAINDFATRSRS----VVGDALEFGNSWKLSPSCPDALAPKDP 1763
Query: 2254 CTPEQQESFGGPDACGVISATDGP-LAPCHGLVPPAQYFQGCLLDACQVQ--GHPGGLCP 2310
CT C ++ GP A C V +Y++ C+ DAC G C
Sbjct: 1764 CTANPFRKSWAQKQCSIL---HGPTFAACRSQVDSTKYYEACVNDACACDSGGDCECFCT 1820
Query: 2311 AVATYVAACQAAGAQLGEWRRPDFCPLQCPAHS-------HYELCGDSCPVSC--PS--- 2358
AVA Y AC AG + WR PD CPL C ++ HY+ CG C +C PS
Sbjct: 1821 AVAAYAQACHDAGLCV-SWRTPDTCPLFCDFYNPHGGCEWHYQPCGAPCLKTCRNPSGHC 1879
Query: 2359 ---LSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCL-HDGRYYPLGEVFYPGPECE 2414
L EGC C + + D V QCGC DG YY +G C+
Sbjct: 1880 LVDLPGLEGCYPKCP-----PSQPFFNEDQMKCVAQCGCYDKDGNYYDVGARVPTAENCQ 1934
Query: 2415 RRCECGPGGHVTCQEGAACGPHEECR----------LEDGVQACHATGCGRCLANGGI 2462
C C P G AC E R DG+ AC CG +NG I
Sbjct: 1935 -SCNCTPSGIQCAHSLEACTCTYEDRTYSYQDVIYNTTDGLGACLIAICG---SNGTI 1988
Score = 251 bits (641), Expect = 8e-66
Identities = 250/966 (25%), Positives = 373/966 (38%), Gaps = 180/966 (18%)
Query: 455 CQVVGGKAGCV-AESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSV 513
C GG C C QG H +T+D + YD+ G CSY + + C++ +F+V
Sbjct: 1066 CTCSGGLWQCQDLPCPGTCSVQGGAHISTYDEKLYDLHGDCSYVLSKKCADS----SFTV 1121
Query: 514 EAKNEHRG-SRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQ 572
A+ G + + + VT+ ++ G V +++ ++LP+S + L
Sbjct: 1122 LAELRKCGLTDNENCLKAVTLSLDGGDTAIRVQADGGVFLNSIYTQLPLSAANITLFT-P 1180
Query: 573 SGPRAVVELVFGLVVTYDWD--CQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALA 630
S VV+ GL + Q+ + L Q Q+CGLCGN+N + ADDF G +
Sbjct: 1181 SSFFIVVQTGLGLQLLVQLVPLMQVFVRLDPAHQGQMCGLCGNFNQNQADDFTALSGVVE 1240
Query: 631 PDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQ--AQHYEGDRLCGMLTKLDGPFAVCH 688
FA++WK + ++ C + A+H+ C LT + F+ CH
Sbjct: 1241 ATGAAFANTWKAQAACANARNSFEDPCSLSVENENYARHW-----CSRLTDPNSAFSRCH 1295
Query: 689 DTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSP--ANCPLSCP 746
++P+PF C++D C LC LS+Y AC G+ + DWR +CP
Sbjct: 1296 SIINPKPFHSNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLSDWRDGVCTKYMQNCP 1355
Query: 747 ANSRYELCGPACPTSCNG-AAAPSNCS-GRPCVEGCVCLPG-FVASGGACVPASSCGCTF 803
+ RY AC +C G + A CS V+GC C G F+ GACVPA C C
Sbjct: 1356 KSQRYAYVVDACQPTCRGLSEADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQECPCYA 1415
Query: 804 QGLQLAPGQEVWADELCQRRCT-----CNGATHQ-----------VTCRDKQSCPAGERC 847
G LAPG EV DE CT C GA+ Q + C + + G C
Sbjct: 1416 HGTVLAPG-EVVHDEGAVCSCTGGKLSCLGASLQKSTGCAAPMVYLDCSNSSAGTPGAEC 1474
Query: 848 -------------------------SVQNGLLGCYPDRFGTCQGSG-----------DPH 871
V +G GC + C + D +
Sbjct: 1475 LRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKPGETIRVDCN 1534
Query: 872 YVSFDGRRFD-----FMGTCT--------------YLLVGS---------CGQNAALPAF 903
+ RR++ +GTC Y GS CG N F
Sbjct: 1535 TCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNTTHGTF 1594
Query: 904 RVLVENEHRGSQTVSYTRAVRV--------------------EARGVKVAVRREYPGQVL 943
R++ EN G+ + ++A+++ R V R+ P
Sbjct: 1595 RIVTENIPCGTTGTTCSKAIKLFVEVRTAPAVSTPDPAANEPAPREASVGFRQRLPPLQS 1654
Query: 944 VDDVLQYLPFQA------ADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAE 997
+ +LQ F+A D ++ G V+ T G+ V++D V ++ Y
Sbjct: 1655 YELILQEGTFKAVARGPGGDPPYKIRYMGIFLVIET-HGMAVSWDRKTSVFIRLHQDYKG 1713
Query: 998 ALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQ 1057
+CGLCGNF+ + +D A R +AL FGNSW + P C P D A
Sbjct: 1714 RVCGLCGNFDDNAINDFATRSRSVVGDALEFGNSW--KLSPSC----PDALAPKDPCTAN 1767
Query: 1058 QLQ---SKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLP--GQSGPLCDALATY 1112
+ ++ +C IL P F C S++D CV D C G C A+A Y
Sbjct: 1768 PFRKSWAQKQCSILHGP--TFAACRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAAY 1825
Query: 1113 AAACQAAGATVHPWRSEELCPLSCP---PHS----HYEACSYGCPLSCGD------LPVP 1159
A AC AG V WR+ + CPL C PH HY+ C C +C + + +P
Sbjct: 1826 AQACHDAGLCV-SWRTPDTCPLFCDFYNPHGGCEWHYQPCGAPCLKTCRNPSGHCLVDLP 1884
Query: 1160 GGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQ-GTYHPPGQTFYPGPGCDSLCHCQE 1218
G G C+ C + F + + +A CGC + G Y+ G C S C+C
Sbjct: 1885 GLEG--CYPKCPPSQPF-FNEDQMKCVAQCGCYDKDGNYYDVGARVPTAENCQS-CNCTP 1940
Query: 1219 GGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVL 1278
G+ S C + D Y T DG +G C+ +
Sbjct: 1941 SGIQCAHSLE--------------ACTCTYEDRTYSYQDVIYNTTDG-----LGACLIAI 1981
Query: 1279 AQTCGT 1284
+ GT
Sbjct: 1982 CGSNGT 1987
Score = 213 bits (542), Expect = 2e-54
Identities = 168/585 (28%), Positives = 253/585 (43%), Gaps = 61/585 (10%)
Query: 461 KAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHR 520
+A A + VC G HY TFDG + G C+Y E C F+++ +
Sbjct: 70 RASNPAHNGRVCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGA--AYEDFNIQLRRSQE 127
Query: 521 GSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVE 580
+ + V ++ + LT+G V LV+ LP S+ + + QS VE
Sbjct: 128 SAAPT--LSRVLMKVDGVVIQLTKGSV---LVNGHPVLLP--FSQSGVLIQQSSSYTKVE 180
Query: 581 LVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPA-DDFLTPDGALAPDAVEFASS 639
GLV+ ++ D L L L ++ ++ CGLCG++NG P + L+ + L P +EF +
Sbjct: 181 ARLGLVLMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTP--MEFGNL 238
Query: 640 WKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQ 699
K+DD C+D C+ G E L G L F+ C +D +LE
Sbjct: 239 QKMDDPTEQCQDPVPEPPRNCSTGFGICEE--LLHGQL------FSGCVALVDVGSYLEA 290
Query: 700 CVYDLCVVGGERL--SLCRGLSAYAQACLELGISVGDWRSPANCPLSCPANSRYELCGPA 757
C DLC L +C L+ Y++ C G DWR P CP CP N +Y C
Sbjct: 291 CRQDLCFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSP 350
Query: 758 CPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASG---GACVPASSCGCTFQGLQLAPGQEV 814
C +C+ C CV GC C G V CVP S C C + G APG
Sbjct: 351 CADTCSNQEHSRACEDH-CVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATY 409
Query: 815 WADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVS 874
D C CTC+G + +C++ CP GTC G H+ +
Sbjct: 410 STD--C-TNCTCSGG--RWSCQE-VPCP-------------------GTCSVLGGAHFST 444
Query: 875 FDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRG-SQTVSYTRAVRVEARGVKVA 933
FDG+++ G C+Y+L C + AF VL E G + + + ++V + G +
Sbjct: 445 FDGKQYTVHGDCSYVLTKPCDSS----AFTVLAELRRCGLTDSETCLKSVTLSLDGAQTV 500
Query: 934 VRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVV-RTDFGLTVTYDW--NARVTAK 990
V + G+V ++ + LP AA+ V +FR ++ +T GL + ++ +
Sbjct: 501 VVIKASGEVFLNQIYTQLPISAAN--VTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQ 558
Query: 991 VPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEE 1035
+ CGLCGNFN ADD G A A AF N+++ +
Sbjct: 559 LAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKTQ 603
Score = 202 bits (514), Expect = 4e-51
Identities = 170/597 (28%), Positives = 241/597 (40%), Gaps = 79/597 (13%)
Query: 2074 CQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-----SQAV 2128
C WG HY T DG F F G C Y+ S C E+F + + S+ +
Sbjct: 81 CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGA---AYEDFNIQLRRSQESAAPTLSRVL 137
Query: 2129 SYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLS 2188
V +Q+ S+ V+G V LPF +L S + V GL
Sbjct: 138 MKVDGVVIQLTKGSVL----------VNGHPVLLPFSQSGVL-IQQSSSYTKVEARLGLV 186
Query: 2189 LAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPA-DDLKAVGGKPAGWQVGGAQGCGECVS 2247
L ++ D + L + YA CGLCG++N P +L + K + G Q + +
Sbjct: 187 LMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTPMEFGNLQKMDD-PT 245
Query: 2248 KPCPSPCTPEQQESFGGPDACGVISATDGPL-APCHGLVPPAQYFQGCLLDACQVQGHP- 2305
+ C P + G C + G L + C LV Y + C D C +
Sbjct: 246 EQCQDPVPEPPRNCSTGFGICEEL--LHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDL 303
Query: 2306 -GGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEG 2364
+C +A Y C AG +WR PDFCP +CP + Y C C +C +
Sbjct: 304 LSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEHSRA 363
Query: 2365 CESACREGCVCDAGFVLS--GDT-CVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGP 2421
CE C GC C G VL G T CVPV +C C+++G Y G + +C C C
Sbjct: 364 CEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATY--STDC-TNCTCS- 419
Query: 2422 GGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCSYV 2481
GG +CQE C G C GG H+ T DG+ Y +HG CSYV
Sbjct: 420 GGRWSCQE-VPCP-------------------GTCSVLGGAHFSTFDGKQYTVHGDCSYV 459
Query: 2482 LAQVCHPKPGDEDFSIVLEKNAAG--DLQRLLVTV------AGQVVSLAQGQQVTVDGEA 2533
L + C F+++ E G D + L +V A VV + +V ++
Sbjct: 460 LTKPC----DSSAFTVLAELRRCGLTDSETCLKSVTLSLDGAQTVVVIKASGEVFLNQIY 515
Query: 2534 VALPVAVGRVRVTAEGRNMVL-QTTKGLRLLFD--GDAHLLMSIPSPFRGRLCGLCGNFN 2590
LP++ V + ++ QT+ GL+L L M + RG+ CGLCGNFN
Sbjct: 516 TQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFN 575
Query: 2591 GNWSDDFVLPNG----SAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAP 2643
+DDF +G +AA+ TF P + C L+ E AP
Sbjct: 576 SIQADDFRTLSGVVEATAAAFFNTFKTQAACPNIRNSFEDPCS-------LSVENAP 625
Score = 184 bits (467), Expect = 1e-45
Identities = 153/557 (27%), Positives = 247/557 (44%), Gaps = 61/557 (10%)
Query: 2445 VQACHATGCGR-CLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVL---E 2500
V+A + GR C G HY T DG V+ G C+YV ++ C EDF+I L +
Sbjct: 69 VRASNPAHNGRVCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGA--AYEDFNIQLRRSQ 126
Query: 2501 KNAAGDLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGL 2560
++AA L R+L+ V G V+ L +G V V+G V LP + V + ++ GL
Sbjct: 127 ESAAPTLSRVLMKVDGVVIQLTKGS-VLVNGHPVLLPFSQSGVLIQQSSSYTKVEARLGL 185
Query: 2561 RLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGS 2620
L+++ D LL+ + + + + CGLCG+FNG +L + + + +E FG +
Sbjct: 186 VLMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTPME-FGNLQKMDDP 244
Query: 2621 SKGCGEGC--GPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVY 2678
++ C + P+ C C +L + Q F+ C A++ Y C
Sbjct: 245 TEQCQDPVPEPPRNCSTGFG----------ICEELLHGQ-LFSGCVALVDVGSYLEACRQ 293
Query: 2679 DLCAQKGDK--AFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQG 2736
DLC + + +C +LA Y+ C AG + WR FCP CP + Y C C
Sbjct: 294 DLCFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCAD 353
Query: 2737 SCAALSGLTGCTTRCFEGCECDDRFLL---SQGVCIPVQDCGCTHNG-RYLPVNSSLLTS 2792
+C+ C C GC C + +L Q C+PV C C +NG Y P + ++
Sbjct: 354 TCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAP--GATYST 411
Query: 2793 DCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGA 2852
DC+ C+CS +CQ CP G C + GA+ +TFDG +
Sbjct: 412 DCT-NCTCSGGR-WSCQEVPCP------------------GTCSVLGGAHFSTFDGKQYT 451
Query: 2853 TTSPGVYELSSRCPGLQNTIPWYRVVAEVQICH-GKTEAVGQVHIFFQDGMVTLTPNKG- 2910
Y L+ C + V+AE++ C +E + DG T+ K
Sbjct: 452 VHGDCSYVLTKPCDSSA-----FTVLAELRRCGLTDSETCLKSVTLSLDGAQTVVVIKAS 506
Query: 2911 --VWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQ--VWLGANGKVAVIVSNDHAG 2966
V++N + LP A+V++ R ++ + G+Q + L ++ + ++ G
Sbjct: 507 GEVFLNQIYTQLPI-SAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRG 565
Query: 2967 KLCGACGNFDGDQTNDW 2983
+ CG CGNF+ Q +D+
Sbjct: 566 QTCGLCGNFNSIQADDF 582
Score = 176 bits (447), Expect = 2e-43
Identities = 153/568 (26%), Positives = 236/568 (41%), Gaps = 58/568 (10%)
Query: 864 CQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRV-LVENEHRGSQTVSYTRA 922
C G HY +FDG F F G C Y+ CG AA F + L ++ + T+S
Sbjct: 81 CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCG--AAYEDFNIQLRRSQESAAPTLS---R 135
Query: 923 VRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYD 982
V ++ GV + + + G VLV+ LPF + +Q + V GL + ++
Sbjct: 136 VLMKVDGVVIQLTK---GSVLVNGHPVLLPFSQSGVLIQ--QSSSYTKVEARLGLVLMWN 190
Query: 983 WNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGA 1042
+ + ++ + YA CGLCG+FNG P L + FGN Q+ P
Sbjct: 191 HDDSLLLELDTKYANKTCGLCGDFNGMPVVS-ELLSHNTKLTPMEFGNL-QKMDDPTEQC 248
Query: 1043 TEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQS 1102
+P P + + + G L F C + +D + C D C
Sbjct: 249 QDPVPEPPRNCSTGFGICEELLHGQL------FSGCVALVDVGSYLEACRQDLCFCEDTD 302
Query: 1103 --GPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPVPG 1160
+C LA Y+ C AG WR + CP CP + Y C C +C +
Sbjct: 303 LLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEHSR 362
Query: 1161 GCGSECHEGCVCDEGFALSG---ESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQ 1217
C C GC C EG L C+P++ C CV+ G + PG T+ C + C C
Sbjct: 363 ACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATY--STDCTN-CTC- 418
Query: 1218 EGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYV 1277
GG SC+ C TC G H++TFDG+++ G C YV
Sbjct: 419 SGGRWSCQEVPC-------------------PGTCSVLGGAHFSTFDGKQYTVHGDCSYV 459
Query: 1278 LAQTCGTRPGLHRFAVLQENVAWG-NGRVSVTRVITVQVANF-TLRLEQRQWKVTVNGVD 1335
L + C + F VL E G + + +T+ + T+ + + +V +N +
Sbjct: 460 LTKPCDS----SAFTVLAELRRCGLTDSETCLKSVTLSLDGAQTVVVIKASGEVFLNQIY 515
Query: 1336 MKLPVVLANGQI-RASQHGSDVVIETDFGLRVAYDLVYYVR--VTVPGNYYQQMCGLCGN 1392
+LP+ AN I R S ++ +T GL++ LV ++ + + Q CGLCGN
Sbjct: 516 TQLPISAANVTIFRPSTF--FIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGN 573
Query: 1393 YNGDPKDDFQKPNGSQAGNANEFGNSWE 1420
+N DDF+ +G A F N+++
Sbjct: 574 FNSIQADDFRTLSGVVEATAAAFFNTFK 601
Score = 173 bits (439), Expect = 2e-42
Identities = 158/579 (27%), Positives = 240/579 (41%), Gaps = 93/579 (16%)
Query: 1252 CQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVI 1311
C G HY TFDG F F G C YV ++ CG + +Q + + +++RV+
Sbjct: 81 CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAA---YEDFNIQLRRSQESAAPTLSRVL 137
Query: 1312 TVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLV 1371
++V ++L + V VNG + LP + + Q S +E GL + ++
Sbjct: 138 -MKVDGVVIQLTKGS--VLVNGHPVLLP--FSQSGVLIQQSSSYTKVEARLGLVLMWNHD 192
Query: 1372 YYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPP 1431
+ + + Y + CGLCG++NG P + ++ EFGN + P C P
Sbjct: 193 DSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKL-TPMEFGNLQKMDDPTEQCQDP 251
Query: 1432 TPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDL 1491
P PP +C EL G L S C LVD L+ C DL
Sbjct: 252 VPEPP--RNCSTGFGICEEL--------LHGQL------FSGCVALVDVGSYLEACRQDL 295
Query: 1492 CLGGGN--LSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGC 1549
C LS +C + Y C AGG + WR FCP +CP N Y C C+ C
Sbjct: 296 CFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTC 355
Query: 1550 SALSAPPQCQDGCAEGCQCDSGFLYN--GQ-ACVPIQQCGCYHNGVYYEPEQTVLIDNCR 1606
S C+D C GC C G + + GQ CVP+ +C C +NG Y P T D C
Sbjct: 356 SNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYSTD-C- 413
Query: 1607 QQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCL 1666
CTC G+ CQE C PG
Sbjct: 414 TNCTCSGGR-WSCQEVPC-PG--------------------------------------- 432
Query: 1667 PNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRG- 1725
TC + G H+ +FDG+++ G C+YVL T C + FTV + + G
Sbjct: 433 -----TCSVLGGAHFSTFDGKQYTVHGDCSYVL-TKPCDS------SAFTVLAELRRCGL 480
Query: 1726 NPAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALL 1785
+ + ++ VT++ G + G+ V +N + T LP+S A+ +++ + ++ ++
Sbjct: 481 TDSETCLKSVTLSLDGAQTVVVIKASGE--VFLNQIYTQLPISAAN--VTIFRPSTFFII 536
Query: 1786 V-ADFGLQVSYDW--NWRVDVTLPSSYHGAVCGLCGNMD 1821
GLQ++ ++ + L G CGLCGN +
Sbjct: 537 AQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFN 575
Score = 171 bits (432), Expect = 1e-41
Identities = 169/649 (26%), Positives = 257/649 (39%), Gaps = 82/649 (12%)
Query: 1673 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYV 1732
C WG HY +FDG F F G CNYV + C G + + ++Q P +S V
Sbjct: 81 CSTWGSFHYKTFDGDVFRFPGLCNYVFSEH-C-GAAYEDFN--IQLRRSQESAAPTLSRV 136
Query: 1733 RVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVADFGLQ 1792
+ + ++ K V VNG LP S + + + Q +S + A GL
Sbjct: 137 LMKVDGVV--------IQLTKGSVLVNGHPVLLPFSQSG--VLIQQSSSYTKVEARLGLV 186
Query: 1793 VSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWD 1852
+ ++ + + + L + Y CGLCG+ + P ++ + T P+ G+ + D
Sbjct: 187 LMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLT--PMEFGNLQKMD-D 243
Query: 1853 PLCWDECRGSCPTCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDVC 1912
P ++C+ P P + G G C L G F+ C A V S+ + C D+C
Sbjct: 244 PT--EQCQDPVPEPPRNCST---GFGICEELLHGQ--LFSGCVALVDVGSYLEACRQDLC 296
Query: 1913 MGGGDRDIL---CKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASC 1969
D D+L C LA Y C AG + +DWR C CP N Y C PC +C
Sbjct: 297 FCE-DTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTC 355
Query: 1970 PSPAPLTTPAVCEGPCVEGCQCDAGFVL---SADRCVPLNNGCGCWANGTYHEAGSEFWA 2026
+ CE CV GC C G VL CVP++ C C NG + G+ +
Sbjct: 356 SNQ---EHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSK-CACVYNGAAYAPGATYST 411
Query: 2027 DGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPV-STAECQAWGDPHYVTL 2085
D CT +C G+ CQ V C G H+ T
Sbjct: 412 D-----------------CTNCTCS---------GGRWSCQEVPCPGTCSVLGGAHFSTF 445
Query: 2086 DGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTLQIYNHSLT 2144
DG ++ G C Y+L+ PC + FTV G + + + +SVTL +
Sbjct: 446 DGKQYTVHGDCSYVLTKPC-----DSSAFTVLAELRRCGLTDSETCLKSVTLSLDGAQTV 500
Query: 2145 LSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAA 2204
+ + ++ ++ ++ LP ++ S ++ T+ GL L ++L + A
Sbjct: 501 VVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLA 560
Query: 2205 --YAASLCGLCGNYNQDPADDLKAVGG-----KPAGWQVGGAQGCGECVSKPCPSPC--T 2255
CGLCGN+N ADD + + G A + Q + PC +
Sbjct: 561 PKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKTQAACPNIRNSFEDPCSLS 620
Query: 2256 PEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGH 2304
E G P AC + LA LV P QG + + + GH
Sbjct: 621 VENAPRMGAPSACRTL-----VLALAAMLVVPQAETQGPVEPSWENAGH 664
Score = 170 bits (430), Expect = 2e-41
Identities = 143/549 (26%), Positives = 237/549 (43%), Gaps = 70/549 (12%)
Query: 2456 CLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGD---LQRLLV 2512
C G HY T DG V+ G C+YV ++ C + EDF++ L + G + R+++
Sbjct: 733 CSTWGDFHYKTFDGDVFRFPGLCNYVFSEHC--RAAYEDFNVQLRRGLVGSRPVVTRVVI 790
Query: 2513 TVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLM 2572
G V+ + G V ++G+ LP + + V G + + L L++G+ L+
Sbjct: 791 KAQGLVLEASNGS-VLINGQREELPYSRTGLLVEQSGDYIKVSIRLVLTFLWNGEDSALL 849
Query: 2573 SIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQG 2632
+ + + CGLCG+FNG + + + + + ++ FG + G ++ C + P
Sbjct: 850 ELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLTPLQ-FGNLQKLDGPTEQCPDPL-PLP 907
Query: 2633 CPVCLAEETAPYESNEACGQLRNPQGP-FATCQAVLSPSEYFRQCVYDLCAQKGDKAFLC 2691
C EE + R GP FA C A++ + Y C DLC C
Sbjct: 908 AGNCTDEEGICH---------RTLLGPAFAECHALVDSTAYLAACAQDLCRCP---TCPC 955
Query: 2692 RSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRC 2751
+ Y+ C AG + WR CP CP + + C C +C+ C C
Sbjct: 956 ATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSNPQRAQLCEDHC 1015
Query: 2752 FEGCEC---------DDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSS 2802
+GC C DD ++ C+P+ C CTH GR +S T+ CS SC+
Sbjct: 1016 VDGCFCPPGRSCTVLDD---ITHSGCLPLGQCPCTHGGRTYSPGTSFNTT-CS---SCTC 1068
Query: 2803 SSGL-TCQAAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYEL 2861
S GL CQ CP G C + GA+++T+D Y L
Sbjct: 1069 SGGLWQCQDLPCP------------------GTCSVQGGAHISTYDEKLYDLHGDCSYVL 1110
Query: 2862 SSRCPGLQNTIPWYRVVAEVQICHGKTE---AVGQVHIFFQDG--MVTLTPNKGVWVNGL 2916
S +C T V+AE++ C G T+ + V + G + + + GV++N +
Sbjct: 1111 SKKCADSSFT-----VLAELRKC-GLTDNENCLKAVTLSLDGGDTAIRVQADGGVFLNSI 1164
Query: 2917 RVDLPAEKLASVSVSRTPDGSLLVRQKAGVQVWLGANGKVAVIVSND--HAGKLCGACGN 2974
LP A++++ ++V+ G+Q+ + + V V D H G++CG CGN
Sbjct: 1165 YTQLPLSA-ANITLFTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLDPAHQGQMCGLCGN 1223
Query: 2975 FDGDQTNDW 2983
F+ +Q +D+
Sbjct: 1224 FNQNQADDF 1232
Score = 124 bits (311), Expect = 1e-27
Identities = 135/534 (25%), Positives = 196/534 (36%), Gaps = 101/534 (18%)
Query: 1185 PLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGC 1244
P+A+ CV++ H P + P CD C+ C+ GG
Sbjct: 5365 PVANVTCVNK---HLPIKVSDPSQPCDFHYECE-----------------CECVGGR--G 5402
Query: 1245 VAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGR 1304
+ G+ C G HY+TFDG + F G C YVL + R G N++
Sbjct: 5403 ITPGAGICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFG---------NLSLYLDN 5453
Query: 1305 VSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDF-- 1362
T T A R + +D+ L V + +G+ + + + F
Sbjct: 5454 HYCTASATAAAAAARC---PRALSIHYKSMDIVLTVTMVHGKEEGLILFDQIPVSSGFSK 5510
Query: 1363 -GLRVAYDLVYYVRVTVP---------GNYYQQMC----------GLCGNYNGDPKDDFQ 1402
G+ V+ +RV +P G +Q G CG + +DD
Sbjct: 5511 NGVLVSVLGTTTMRVDIPALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCL 5570
Query: 1403 KPNGSQAGNANEFGNSWEEVVPDSP---CLPPTPCPPGSEDCIPSHK------CPPELEK 1453
+ +G+ A + + +W +VPDS C PT PP + P CPP+
Sbjct: 5571 QRDGTTAASCKDMAKTW--LVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQ--- 5625
Query: 1454 KYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQ 1513
C L+ S + CH LV P CI D C G L + C ++ AY C+
Sbjct: 5626 -----PLCDLMLSQV--FAECHNLVPPGPFFNACISDHCRG--RLEVPCQSLEAYAELCR 5676
Query: 1514 AAGGHVEPWRTET--FCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQC-DS 1570
A G WR T C + CPP Y+ C C++ + PQ +G AEGC C +
Sbjct: 5677 ARGV-CSDWRGATGGLCDLTCPPTKVYKPCGPIQPATCNSRNQSPQL-EGMAEGCFCPED 5734
Query: 1571 GFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEHSCKPGQVC 1630
L+N + +Q C C + + + NC Q C C G V CKP C
Sbjct: 5735 QILFNAHMGICVQACPCVGPDGFPKFPGERWVSNC-QSCVCDEGSVSV----QCKP-LPC 5788
Query: 1631 QPSGGILSC-------VTK----DPCHGVTCRPQETCKEQGGQGVCLPNYEATC 1673
G C VT+ +PC T T VC P E+ C
Sbjct: 5789 DAQGQPPPCNRPGFVTVTRPRAENPCCPETVCVCNTTTCPQSLPVCPPGQESIC 5842
Score = 122 bits (305), Expect = 7e-27
Identities = 123/438 (28%), Positives = 175/438 (39%), Gaps = 70/438 (15%)
Query: 436 VLSPVEPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCS 495
V P +P +C C+ VGG+ + +C G HY+TFDG Y G C+
Sbjct: 5380 VSDPSQPCDFHYEC----ECECVGGRG--ITPGAGICSMWGGSHYSTFDGTSYTFRGNCT 5433
Query: 496 YTM----------VELCSEDDTLPAFSVEAKNEHRGSRRVS--YVGLVTVRAYSHSVSLT 543
Y + + L ++ A + A R R +S Y + V +V++
Sbjct: 5434 YVLMREIHARFGNLSLYLDNHYCTASATAAAAAARCPRALSIHYKSMDIVL----TVTMV 5489
Query: 544 RG-EVGFVLVDNQRSRLPVS--LSEGRLRVYQSGPRAV-VEL-VFGLVVTYDWDCQLALS 598
G E G +L D ++PVS S+ + V G + V++ G+ VT++ A
Sbjct: 5490 HGKEEGLILFD----QIPVSSGFSKNGVLVSVLGTTTMRVDIPALGVSVTFNGQVFQARL 5545
Query: 599 LPARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGC----- 653
+ F + G CG + DD L DG A + A +W + D +DGC
Sbjct: 5546 PYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTWLVPDSR---KDGCWAPTG 5602
Query: 654 ----------QNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYD 703
++ P TP Q LC ++ L FA CH+ + P PF C+ D
Sbjct: 5603 TPPTASPAAPVSSTPTPTPCPPQ-----PLCDLM--LSQVFAECHNLVPPGPFFNACISD 5655
Query: 704 LCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPAN--CPLSCPANSRYELCGPACPTS 761
C G C+ L AYA+ C G+ DWR C L+CP Y+ CGP P +
Sbjct: 5656 HC--RGRLEVPCQSLEAYAELCRARGV-CSDWRGATGGLCDLTCPPTKVYKPCGPIQPAT 5712
Query: 762 CNGAAAPSNCSGRPCVEGCVCLPG---FVASGGACVPASSCGCTFQGLQLAPGQEVWADE 818
CN G EGC C F A G CV A C G PG E W
Sbjct: 5713 CNSRNQSPQLEG--MAEGCFCPEDQILFNAHMGICVQACPC-VGPDGFPKFPG-ERWVSN 5768
Query: 819 LCQRRCTCNGATHQVTCR 836
CQ C C+ + V C+
Sbjct: 5769 -CQ-SCVCDEGSVSVQCK 5784
Score = 120 bits (301), Expect = 2e-26
Identities = 125/472 (26%), Positives = 176/472 (37%), Gaps = 52/472 (11%)
Query: 1637 LSCVTK-------DPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKF 1689
++CV K DP + C+ GG+G+ P C +WG HY +FDG +
Sbjct: 5369 VTCVNKHLPIKVSDPSQPCDFHYECECECVGGRGIT-PG-AGICSMWGGSHYSTFDGTSY 5426
Query: 1690 DFQGTCNYVLATTGCPGVSTQGL------TPFTVTTKNQNRGNPAVSYVRVVTVAALGTN 1743
F+G C YVL L + T P + ++ + T
Sbjct: 5427 TFRGNCTYVLMREIHARFGNLSLYLDNHYCTASATAAAAAARCPRALSIHYKSMDIVLTV 5486
Query: 1744 ISIHKDEIGKVRVCVNGVLTALPVSVADGR--ISVAQGASKALLVADFGLQVSYDWNWRV 1801
+H E G + + +PVS + + V+ + + V L VS +N +V
Sbjct: 5487 TMVHGKEEGLI------LFDQIPVSSGFSKNGVLVSVLGTTTMRVDIPALGVSVTFNGQV 5540
Query: 1802 -DVTLPSS-YHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAP-GWDPLCWDE 1858
LP S +H G CG N +D + +GT A S +W P CW
Sbjct: 5541 FQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTWLVPDSRKDGCWAP 5600
Query: 1859 CRGSCPTC-PEDRLEQYEGPGFCGPLASGT---GGPFTTCHAHVPPESFFKGCVLDVCMG 1914
G+ PT P + P C P F CH VPP FF C+ D C G
Sbjct: 5601 T-GTPPTASPAAPVSSTPTPTPCPPQPLCDLMLSQVFAECHNLVPPGPFFNACISDHCRG 5659
Query: 1915 GGDRDILCKALASYVAACQAAGVVIEDWRAQVG--CEITCPENSHYEVCGPPCPASCPSP 1972
++ C++L +Y C+A GV DWR G C++TCP Y+ CGP PA+C S
Sbjct: 5660 R--LEVPCQSLEAYAELCRARGVC-SDWRGATGGLCDLTCPPTKVYKPCGPIQPATCNS- 5715
Query: 1973 APLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQ 2032
EG EGC C +L C C + + E W Q
Sbjct: 5716 --RNQSPQLEG-MAEGCFCPEDQILFNAHMGICVQACPCVGPDGFPKFPGERWVSN--CQ 5770
Query: 2033 WCRCGPGGGSLVCTPASCGL----------GEVCGLLPSGQHGCQPVSTAEC 2074
C C G S+ C P C G V P ++ C P + C
Sbjct: 5771 SCVCDEGSVSVQCKPLPCDAQGQPPPCNRPGFVTVTRPRAENPCCPETVCVC 5822
Score = 114 bits (286), Expect = 1e-24
Identities = 137/557 (24%), Positives = 186/557 (33%), Gaps = 89/557 (15%)
Query: 2339 CPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCG----- 2393
C H + +CP S P +S+ + GC D +P+ Q
Sbjct: 5295 CNQHCDIDRFQGACPTSPPPVSSAPLSSPSPAPGC----------DNAIPLRQVNETWTL 5344
Query: 2394 -------CLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQ 2446
C+ D R L P P C C H EC E
Sbjct: 5345 ENCTVARCVGDNRVVLLD----PKPVANVTCVNKHLPIKVSDPSQPCDFHYECECECVGG 5400
Query: 2447 ACHATGCGRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPG------DEDFSIVLE 2500
G G C GG HY T DG Y G+C+YVL + H + G D +
Sbjct: 5401 RGITPGAGICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTASA 5460
Query: 2501 KNAAG---------------DLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRV 2545
AA D+ + V G+ L Q+ V V V +
Sbjct: 5461 TAAAAAARCPRALSIHYKSMDIVLTVTMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGT 5520
Query: 2546 TAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAA 2605
T ++ G+ + F+G S F G CG N DD + +G+ A
Sbjct: 5521 TTMRVDI---PALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTA 5577
Query: 2606 SSVETFGAAWRAPGSSK-GCGEGCG-----PQGCPVCLAEETAPYESNEACGQLRNPQGP 2659
+S + W P S K GC G PV P C + +
Sbjct: 5578 ASCKDMAKTWLVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQPLCDLMLSQ--V 5635
Query: 2660 FATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWR--TDSFC 2717
FA C ++ P +F C+ D C +G C+SL AY C+A GV WR T C
Sbjct: 5636 FAECHNLVPPGPFFNACISDHC--RGRLEVPCQSLEAYAELCRARGVC-SDWRGATGGLC 5692
Query: 2718 PLHCPAHSHYSICTRTCQGSCAA------LSGLTGCTTRCFEGCEC-DDRFLLSQGVCIP 2770
L CP Y C +C + L G+ EGC C +D+ L + + I
Sbjct: 5693 DLTCPPTKVYKPCGPIQPATCNSRNQSPQLEGMA-------EGCFCPEDQILFNAHMGIC 5745
Query: 2771 VQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSS------GLTCQAAGCP-----PGRVC 2819
VQ C C + S+C + C C S L C A G P PG V
Sbjct: 5746 VQACPCVGPDGFPKFPGERWVSNC-QSCVCDEGSVSVQCKPLPCDAQGQPPPCNRPGFVT 5804
Query: 2820 EVKAEARNCWATRGLCV 2836
+ A N +CV
Sbjct: 5805 VTRPRAENPCCPETVCV 5821
Score = 97.8 bits (242), Expect = 1e-19
Identities = 127/503 (25%), Positives = 182/503 (36%), Gaps = 75/503 (14%)
Query: 780 CVCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQ-RRCTCNGAT-------- 830
C P V+S P+ + GC + L E W E C RC +
Sbjct: 5308 CPTSPPPVSSAPLSSPSPAPGCD-NAIPLRQVNETWTLENCTVARCVGDNRVVLLDPKPV 5366
Query: 831 HQVTCRDK----------QSCPAGERCSVQN-GLLGCYPDRFGTCQGSGDPHYVSFDGRR 879
VTC +K Q C C + G G P G C G HY +FDG
Sbjct: 5367 ANVTCVNKHLPIKVSDPSQPCDFHYECECECVGGRGITPGA-GICSMWGGSHYSTFDGTS 5425
Query: 880 FDFMGTCTYLLVGSCGQNAALPAFRVLVENEH------RGSQTVSYTRAVRVEARGVKVA 933
+ F G CTY+L+ +A + ++N + + RA+ + + + +
Sbjct: 5426 YTFRGNCTYVLMREI--HARFGNLSLYLDNHYCTASATAAAAAARCPRALSIHYKSMDIV 5483
Query: 934 -----VRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYD---WNA 985
V + G +L D + F V V V G++VT++ + A
Sbjct: 5484 LTVTMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMRVDIPALGVSVTFNGQVFQA 5543
Query: 986 RVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSW--QEETRPGCGAT 1043
R+ + + E CG C N + DD R G AA+ +W + + GC A
Sbjct: 5544 RLPYSLFHNNTEGQCGTCTN---NQRDDCLQRDGTTAASCKDMAKTWLVPDSRKDGCWA- 5599
Query: 1044 EPGDCPKLDSLVAQQLQSKNECGILADP------KGPFRECHSKLDPQGAVRDCVYDRCL 1097
P P S A + P F ECH+ + P C+ D C
Sbjct: 5600 -PTGTPPTASPAAPVSSTPTPTPCPPQPLCDLMLSQVFAECHNLVPPGPFFNACISDHC- 5657
Query: 1098 LPGQSGPLCDALATYAAACQAAGATVHPWRSEE--LCPLSCPPHSHYEACSYGCPLSC-- 1153
G+ C +L YA C+A G WR LC L+CPP Y+ C P +C
Sbjct: 5658 -RGRLEVPCQSLEAYAELCRARG-VCSDWRGATGGLCDLTCPPTKVYKPCGPIQPATCNS 5715
Query: 1154 -GDLPVPGGCGSECHEGCVCDEGFAL-SGESCLPLASCGCVHQGTYHPPGQTFYPG---- 1207
P G EGC C E L + + + +C CV P G +PG
Sbjct: 5716 RNQSPQLEGMA----EGCFCPEDQILFNAHMGICVQACPCV-----GPDGFPKFPGERWV 5766
Query: 1208 PGCDSLCHCQEGGL-VSCESSSC 1229
C S C C EG + V C+ C
Sbjct: 5767 SNCQS-CVCDEGSVSVQCKPLPC 5788
Score = 94.7 bits (234), Expect = 1e-18
Identities = 131/572 (22%), Positives = 201/572 (35%), Gaps = 122/572 (21%)
Query: 1922 CKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEV--CGPPCPASCP--SPAPLTT 1977
C+A + + G VI + + GC N H ++ CP S P S APL++
Sbjct: 5267 CRAFGQFFSP----GEVIYNKTDRAGCHFYAVCNQHCDIDRFQGACPTSPPPVSSAPLSS 5322
Query: 1978 PAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCG 2037
P+ G D +PL +E W C+ RC
Sbjct: 5323 PSPAPG---------------CDNAIPLRQV-------------NETWTLENCTV-ARCV 5353
Query: 2038 PGGGSLVCTPAS---------------------CGLGEVCGLLPSGQHGCQPVSTAECQA 2076
++ P C C G G P C
Sbjct: 5354 GDNRVVLLDPKPVANVTCVNKHLPIKVSDPSQPCDFHYECECECVGGRGITP-GAGICSM 5412
Query: 2077 WGDPHYVTLDGHRFDFQGTCEYLLSAPCHGP----PLGAENFTVTVANEHRGSQAVSYTR 2132
WG HY T DG + F+G C Y+L H L +N T A+ + A R
Sbjct: 5413 WGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCT-ASATAAAAAARCPR 5471
Query: 2133 SVTLQIYNHSLTLS-----ARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTS-G 2186
++++ + + L+ + + D + V+ F + +L + L + V + G
Sbjct: 5472 ALSIHYKSMDIVLTVTMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMRVDIPALG 5531
Query: 2187 LSLAFDGDSFVRLRVP-AAYAASLCGLCGNYNQDPADDLKAVGGKPAG--------WQVG 2237
+S+ F+G F + R+P + + + G CG + DD G A W V
Sbjct: 5532 VSVTFNGQVF-QARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTWLVP 5590
Query: 2238 GAQ--GC-------------GECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCH 2282
++ GC S P P+PC P+ C ++ + A CH
Sbjct: 5591 DSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQ--------PLCDLMLSQ--VFAECH 5640
Query: 2283 GLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWR--RPDFCPLQCP 2340
LVPP +F C+ D C +G C ++ Y C+A G +WR C L CP
Sbjct: 5641 NLVPPGPFFNACISDHC--RGRLEVPCQSLEAYAELCRARGV-CSDWRGATGGLCDLTCP 5697
Query: 2341 AHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVL-SGDTCVPVGQCGCLHDGR 2399
Y+ CG P +C S + E EGC C +L + + V C C+
Sbjct: 5698 PTKVYKPCGPIQPATCNSRNQSPQLEGMA-EGCFCPEDQILFNAHMGICVQACPCVG--- 5753
Query: 2400 YYPLGEVFYPGPECERRCECGPGGHVTCQEGA 2431
P G +PG C+ C EG+
Sbjct: 5754 --PDGFPKFPGERWVSNCQ-----SCVCDEGS 5778
Score = 56.2 bits (134), Expect = 5e-07
Identities = 70/281 (24%), Positives = 98/281 (34%), Gaps = 55/281 (19%)
Query: 2734 CQGSCAALSGLTGC-TTRCFEGCECDDRFLLS-QGVCIPVQDCGCTHN-GRYLPVNSSLL 2790
C SC L GC +T C GC C + G CI +DC C HN Y P +
Sbjct: 1474 CLRSCHTLD--VGCFSTHCVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKP--GETI 1529
Query: 2791 TSDCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGAR 2850
DC+ C+C + C C G CV + TFDG R
Sbjct: 1530 RVDCN-TCTCRNRR-WECSHRLC------------------LGTCVAYGDGHFITFDGDR 1569
Query: 2851 GATTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGK-TEAVGQVHIFFQDGMVTLTPNK 2909
+ Y L+ G T +R+V E C T + +F +
Sbjct: 1570 YSFEGSCEYILAQDYCGDNTTHGTFRIVTENIPCGTTGTTCSKAIKLFVEVRTAPAVSTP 1629
Query: 2910 GVWVN---------GLRVDLP--------AEKLASVSVSRTPDGS----------LLVRQ 2942
N G R LP ++ +V+R P G LV +
Sbjct: 1630 DPAANEPAPREASVGFRQRLPPLQSYELILQEGTFKAVARGPGGDPPYKIRYMGIFLVIE 1689
Query: 2943 KAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTNDW 2983
G+ V V + + D+ G++CG CGNFD + ND+
Sbjct: 1690 THGMAVSWDRKTSVFIRLHQDYKGRVCGLCGNFDDNAINDF 1730
Score = 35.8 bits (81), Expect = 0.66
Identities = 50/202 (24%), Positives = 66/202 (32%), Gaps = 54/202 (26%)
Query: 2202 PAAYAASLCGLCGNYNQDPA----DDLKAVGGKPAGWQVGGAQG--CGECVSKPCPSP-- 2253
P A +C QDP +D P G++ G CGECV C +P
Sbjct: 5874 PGALPCHMCTCLSGDTQDPTVQCQEDACNNTTCPQGFEYKRVAGQCCGECVQTACLTPDG 5933
Query: 2254 ----------------CTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLD 2297
CT E+ GG A+ ++ C G + C D
Sbjct: 5934 QPVQLNETWVNSHVDNCTVYLCEAEGGVHLLTPQPASCPDVSSCRGSLRKTGCCYSCEED 5993
Query: 2298 ACQVQ------GHPG-----------GLCPAVATYVAACQAAGAQLG--EWRR--PDFCP 2336
+CQV+ H G G CP + Y A QA Q + RR + P
Sbjct: 5994 SCQVRINTTILWHQGCETEVNITFCEGSCPGASKYSAEAQAMQHQCTCCQERRVHEETVP 6053
Query: 2337 LQCP---------AHSHYELCG 2349
L CP H+ LCG
Sbjct: 6054 LHCPNGSAILHTYTHAVQVLCG 6075
>gi|89191868 von Willebrand factor preproprotein [Homo sapiens]
Length = 2813
Score = 383 bits (984), Expect = e-105
Identities = 345/1284 (26%), Positives = 489/1284 (38%), Gaps = 202/1284 (15%)
Query: 864 CQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAV 923
C G +FDG + F G C+YLL G C + + F ++ + + + VS + +
Sbjct: 35 CSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRS----FSII--GDFQNGKRVSLSVYL 88
Query: 924 RVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDW 983
G + G V D +P+ A+ G G + +G D
Sbjct: 89 -----GEFFDIHLFVNGTVTQGDQRVSMPY-ASKGLYLETEAGYYKLSGEAYGFVARIDG 142
Query: 984 NARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEET-RPGCGA 1042
+ + Y CGLCGNFN DD + G ++ F NSW + C
Sbjct: 143 SGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQWCER 202
Query: 1043 TEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQS 1102
P S Q +C +L F CH +DP+ V C C G
Sbjct: 203 ASPPSSSCNISSGEMQKGLWEQCQLLKSTS-VFARCHPLVDPEPFVALCEKTLCECAGGL 261
Query: 1103 GPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPVPGGC 1162
C AL YA C G ++ W C CP Y C C +C L + C
Sbjct: 262 ECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQSLHINEMC 321
Query: 1163 GSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLV 1222
C +GC C EG L C+ C CVH G +PPG + C++ C C+ +
Sbjct: 322 QERCVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYPPGTSL--SRDCNT-CICRNSQWI 378
Query: 1223 SCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTC 1282
C + C P E C +G H+ +FD R F F G C Y+LA+ C
Sbjct: 379 -CSNEEC-PGE------------------CLVTGQSHFKSFDNRYFTFSGICQYLLARDC 418
Query: 1283 GTRPGLHRFAVLQENVAWGNGRVSV-TRVITVQVA---NFTLRLEQRQWKVTVNGVDMKL 1338
H F+++ E V + R +V TR +TV++ N ++L+ V ++G D++L
Sbjct: 419 QD----HSFSIVIETVQCADDRDAVCTRSVTVRLPGLHNSLVKLKHGAG-VAMDGQDVQL 473
Query: 1339 PVVLANGQIRASQHGSDVVIETDFG--LRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGD 1396
P L G +R QH + +G L++ +D + V + Y + CGLCGNYNG+
Sbjct: 474 P--LLKGDLRI-QHTVTASVRLSYGEDLQMDWDGRGRLLVKLSPVYAGKTCGLCGNYNGN 530
Query: 1397 PKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQ 1456
DDF P+G +FGN+W+ C +D H P L +
Sbjct: 531 QGDDFLTPSGLAEPRVEDFGNAWKL---HGDC----------QDLQKQHSDPCALNPRMT 577
Query: 1457 K--EEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQA 1514
+ EE C +L+SPT +CH+ V P L++C +D+C LC + +Y +AC
Sbjct: 578 RFSEEACAVLTSPT--FEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALASYAAACAG 635
Query: 1515 AGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQ-CQDGCAEGCQCDSGFL 1573
G V WR C + CP Y C C+L C +LS P + C + C EGC C G
Sbjct: 636 RGVRVA-WREPGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECNEACLEGCFCPPGLY 694
Query: 1574 YNGQA-CVPIQQCGCY---------------HNGVYYE---------------------- 1595
+ + CVP QC CY H Y E
Sbjct: 695 MDERGDCVPKAQCPCYYDGEIFQPEDIFSDHHTMCYCEDGFMHCTMSGVPGSLLPDAVLS 754
Query: 1596 --------------PEQTVLI---DNCRQQ---CT--CHAGKGMVCQEHSCKPGQVCQPS 1633
P L+ DN R + CT C + C C G +C P
Sbjct: 755 SPLSHRSKRSLSCRPPMVKLVCPADNLRAEGLECTKTCQ-NYDLECMSMGCVSGCLCPP- 812
Query: 1634 GGILS----CVTKDPC----HGVTCRPQETCKEQGGQGVCLPNY--------EATCWLWG 1677
G++ CV + C G P ET K VC +ATC G
Sbjct: 813 -GMVRHENRCVALERCPCFHQGKEYAPGETVKIGCNTCVCRDRKWNCTDHVCDATCSTIG 871
Query: 1678 DPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTP--FTVTTKNQNRGNPAVSYVRVV 1735
HY +FDG K+ F G C YVL C G P F + N+ +P+V + V
Sbjct: 872 MAHYLTFDGLKYLFPGECQYVLVQDYC------GSNPGTFRILVGNKGCSHPSVKCKKRV 925
Query: 1736 TVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSY 1795
T+ G I + E+ R + + V + +L+ L V +
Sbjct: 926 TILVEGGEIELFDGEVNVKRPMKD-----------ETHFEVVESGRYIILLLGKALSVVW 974
Query: 1796 DWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLC 1855
D + + V L +Y VCGLCGN D NND N + +G SW+ C
Sbjct: 975 DRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKV---SSQC 1031
Query: 1856 WDECR----GSCPTCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDV 1911
D + S TC + ++Q C L S F C+ V PE + C+ D
Sbjct: 1032 ADTRKVPLDSSPATCHNNIMKQTMVDSSCRILTSDV---FQDCNKLVDPEPYLDVCIYDT 1088
Query: 1912 CM--GGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENS----------HYE 1959
C GD C +A+Y C G V+ WR C +C E + Y
Sbjct: 1089 CSCESIGDCACFCDTIAAYAHVCAQHGKVV-TWRTATLCPQSCEERNLRENGYECEWRYN 1147
Query: 1960 VCGPPCPASCPSPAPLTTPAVCEGPCVEGC--QCDAGFVLS--ADRCVPLNNGCGCWANG 2015
C P C +C P PL P CVEGC C G +L CV + C G
Sbjct: 1148 SCAPACQVTCQHPEPLACPV----QCVEGCHAHCPPGKILDELLQTCVDPEDCPVCEVAG 1203
Query: 2016 TYHEAGSEFW---ADGTCSQWCRC 2036
+G + +D Q C C
Sbjct: 1204 RRFASGKKVTLNPSDPEHCQICHC 1227
Score = 314 bits (805), Expect = 7e-85
Identities = 231/790 (29%), Positives = 325/790 (41%), Gaps = 90/790 (11%)
Query: 446 GMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSED 505
G CA G R + STA C G TFDG Y G CSY + C +
Sbjct: 19 GTLCAEGTRGR----------SSTARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKR 68
Query: 506 DTLPAFSV--EAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSL 563
+FS+ + +N R S V + + + ++T+G+ QR +P +
Sbjct: 69 ----SFSIIGDFQNGKRVSLSVYLGEFFDIHLFVNG-TVTQGD--------QRVSMPYA- 114
Query: 564 SEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFL 623
S+G ++G + +G V D + L R+ ++ CGLCGN+N DDF+
Sbjct: 115 SKGLYLETEAGYYKLSGEAYGFVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFM 174
Query: 624 TPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGP 683
T +G L D +FA+SW L G+ CE + +C + +G L K
Sbjct: 175 TQEGTLTSDPYDFANSWALSSGEQWCERASPPSS-SCNISSGEMQKGLWEQCQLLKSTSV 233
Query: 684 FAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPL 743
FA CH +DP PF+ C LC G C L YA+ C + G+ + W + C
Sbjct: 234 FARCHPLVDPEPFVALCEKTLCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSP 293
Query: 744 SCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGCTF 803
CPA Y C C +C C R CV+GC C G + G CV ++ C C
Sbjct: 294 VCPAGMEYRQCVSPCARTCQSLHINEMCQER-CVDGCSCPEGQLLDEGLCVESTECPCVH 352
Query: 804 QGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGT 863
G + PG + D CN CR+ Q + E C G
Sbjct: 353 SGKRYPPGTSLSRD--------CN----TCICRNSQWICSNEECP-------------GE 387
Query: 864 CQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVEN-EHRGSQTVSYTRA 922
C +G H+ SFD R F F G C YLL C + +F +++E + + TR+
Sbjct: 388 CLVTGQSHFKSFDNRYFTFSGICQYLLARDCQDH----SFSIVIETVQCADDRDAVCTRS 443
Query: 923 VRVEARGV-KVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTY 981
V V G+ V+ ++ V +D LP D ++Q A VR +G +
Sbjct: 444 VTVRLPGLHNSLVKLKHGAGVAMDGQDVQLPLLKGDLRIQ---HTVTASVRLSYGEDLQM 500
Query: 982 DWN--ARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPG 1039
DW+ R+ K+ YA CGLCGN+NG+ DD G FGN+W+
Sbjct: 501 DWDGRGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLH---- 556
Query: 1040 CGATEPGDCPKLDSLVAQQLQ--------SKNECGILADPKGPFRECHSKLDPQGAVRDC 1091
GDC L + S+ C +L P F CH + P +R+C
Sbjct: 557 ------GDCQDLQKQHSDPCALNPRMTRFSEEACAVLTSP--TFEACHRAVSPLPYLRNC 608
Query: 1092 VYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPL 1151
YD C LC ALA+YAAAC G V WR C L+CP Y C C L
Sbjct: 609 RYDVCSCSDGRECLCGALASYAAACAGRGVRV-AWREPGRCELNCPKGQVYLQCGTPCNL 667
Query: 1152 SCGDLPVPG-GCGSECHEGCVCDEGFALSGE-SCLPLASCGCVHQGTYHPPGQTFYPGPG 1209
+C L P C C EGC C G + C+P A C C + G P F
Sbjct: 668 TCRSLSYPDEECNEACLEGCFCPPGLYMDERGDCVPKAQCPCYYDGEIFQPEDIF---SD 724
Query: 1210 CDSLCHCQEG 1219
++C+C++G
Sbjct: 725 HHTMCYCEDG 734
Score = 308 bits (788), Expect = 7e-83
Identities = 277/1047 (26%), Positives = 389/1047 (37%), Gaps = 205/1047 (19%)
Query: 2070 STAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVS 2129
STA C +G T DG + F G C YLL+ C +F++ + + G +
Sbjct: 31 STARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQ-----KRSFSI-IGDFQNGKR--- 81
Query: 2130 YTRSVTLQIYNHSLTLSARWPRKLQVDGVF------VALPFQLDSLLHAHLSGADVVVTT 2183
V+L +Y L + L V+G V++P+ L +G +
Sbjct: 82 ----VSLSVY-----LGEFFDIHLFVNGTVTQGDQRVSMPYASKGLYLETEAGYYKLSGE 132
Query: 2184 TSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAG--------WQ 2235
G DG ++ + Y CGLCGN+N DD G W
Sbjct: 133 AYGFVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWA 192
Query: 2236 VGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCL 2295
+ + E S P S + G + C ++ +T A CH LV P + C
Sbjct: 193 LSSGEQWCERASPPSSSCNISSGEMQKGLWEQCQLLKSTS-VFARCHPLVDPEPFVALCE 251
Query: 2296 LDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVS 2355
C+ G CPA+ Y C G L W C CPA Y C C +
Sbjct: 252 KTLCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCART 311
Query: 2356 CPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECER 2415
C SL E C+ C +GC C G +L CV +C C+H G+ YP PG R
Sbjct: 312 CQSLHINEMCQERCVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYP------PGTSLSR 365
Query: 2416 RCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLH 2475
C C+ +EEC G CL G H+ + D R +
Sbjct: 366 DCNT-----CICRNSQWICSNEECP-------------GECLVTGQSHFKSFDNRYFTFS 407
Query: 2476 GSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRLLVT---------VAGQVVSLAQGQQ 2526
G C Y+LA+ C D FSIV+E D + + T + +V L G
Sbjct: 408 GICQYLLARDCQ----DHSFSIVIETVQCADDRDAVCTRSVTVRLPGLHNSLVKLKHGAG 463
Query: 2527 VTVDGEAVALPVAVGRVR----VTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRL 2582
V +DG+ V LP+ G +R VTA R L + L++ +DG LL+ + + G+
Sbjct: 464 VAMDGQDVQLPLLKGDLRIQHTVTASVR---LSYGEDLQMDWDGRGRLLVKLSPVYAGKT 520
Query: 2583 CGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETA 2642
CGLCGN+NGN DDF+ P+G A VE FG AW+ G + + Q C
Sbjct: 521 CGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLHGDCQDLQK----QHSDPCALNPRM 576
Query: 2643 PYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQ 2702
S EAC L +P F C +SP Y R C YD+C+ + LC +LA+Y AAC
Sbjct: 577 TRFSEEACAVLTSPT--FEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALASYAAACA 634
Query: 2703 AAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTG-CTTRCFEGCECDDRF 2761
GV V WR C L+CP Y C C +C +LS C C EGC C
Sbjct: 635 GRGVRVA-WREPGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECNEACLEGCFCPPGL 693
Query: 2762 LLSQ-GVCIPVQDCGCTHN--------------------------------GRYLPVNSS 2788
+ + G C+P C C ++ G LP +
Sbjct: 694 YMDERGDCVPKAQCPCYYDGEIFQPEDIFSDHHTMCYCEDGFMHCTMSGVPGSLLP--DA 751
Query: 2789 LLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWAT---RGLCVLSVGANLTT 2845
+L+S S R S S CP + +AE C T L +S+G
Sbjct: 752 VLSSPLSHRSKRSLSCRPPMVKLVCPADNL---RAEGLECTKTCQNYDLECMSMGC---- 804
Query: 2846 FDGARGATTSPGVYELSSRCPGLQNTIPWYRVVAEV------------------------ 2881
G PG+ +RC L+ P + E
Sbjct: 805 ---VSGCLCPPGMVRHENRCVALERC-PCFHQGKEYAPGETVKIGCNTCVCRDRKWNCTD 860
Query: 2882 QICHGKTEAVGQVHIFFQDGMVTLTP------------------------NKG------- 2910
+C +G H DG+ L P NKG
Sbjct: 861 HVCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRILVGNKGCSHPSVK 920
Query: 2911 ------VWVNGLRVDL---------PAEKLASVSVSRTPDGSLLVRQKAGVQVWLGANGK 2955
+ V G ++L P + V + +L+ KA VW +
Sbjct: 921 CKKRVTILVEGGEIELFDGEVNVKRPMKDETHFEVVESGRYIILLLGKALSVVW-DRHLS 979
Query: 2956 VAVIVSNDHAGKLCGACGNFDGDQTND 2982
++V++ + K+CG CGNFDG Q ND
Sbjct: 980 ISVVLKQTYQEKVCGLCGNFDGIQNND 1006
Score = 280 bits (715), Expect = 2e-74
Identities = 222/777 (28%), Positives = 308/777 (39%), Gaps = 100/777 (12%)
Query: 1671 ATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVS 1730
A C L+G ++FDG + F G C+Y+LA GC S F++ QN
Sbjct: 33 ARCSLFGSDFVNTFDGSMYSFAGYCSYLLAG-GCQKRS------FSIIGDFQNGKR---- 81
Query: 1731 YVRVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVAD-- 1788
++S++ E + + VNG +T D R+S+ ASK L +
Sbjct: 82 -----------VSLSVYLGEFFDIHLFVNGTVTQ-----GDQRVSMPY-ASKGLYLETEA 124
Query: 1789 ---------FGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSI 1839
+G D + V L Y CGLCGN + +D + GTL
Sbjct: 125 GYYKLSGEAYGFVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDP 184
Query: 1840 PIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVP 1899
+ SW + C + +C E +G L T F CH V
Sbjct: 185 YDFANSWALSSGEQWC-ERASPPSSSCNISSGEMQKGLWEQCQLLKSTS-VFARCHPLVD 242
Query: 1900 PESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYE 1959
PE F C +C G + C AL Y C G+V+ W C CP Y
Sbjct: 243 PEPFVALCEKTLCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYR 302
Query: 1960 VCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHE 2019
C PC +C S L +C+ CV+GC C G +L CV + C C +G +
Sbjct: 303 QCVSPCARTCQS---LHINEMCQERCVDGCSCPEGQLLDEGLCVE-STECPCVHSGKRYP 358
Query: 2020 AGSEFWAD-GTC----SQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAEC 2074
G+ D TC SQW +C+ C EC
Sbjct: 359 PGTSLSRDCNTCICRNSQW----------ICSNEEC--------------------PGEC 388
Query: 2075 QAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSV 2134
G H+ + D F F G C+YLL+ C TV A++ AV TRSV
Sbjct: 389 LVTGQSHFKSFDNRYFTFSGICQYLLARDCQDHSFSIVIETVQCADDR---DAVC-TRSV 444
Query: 2135 TLQIYN-HSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDG 2193
T+++ H+ + + + +DG V LP L H A V ++ L + +DG
Sbjct: 445 TVRLPGLHNSLVKLKHGAGVAMDGQDVQLPLLKGDLRIQHTVTASVRLSYGEDLQMDWDG 504
Query: 2194 DSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGG--KPAGWQVGGAQGC-GEC--VSK 2248
+ +++ YA CGLCGNYN + DD G +P G A G+C + K
Sbjct: 505 RGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLHGDCQDLQK 564
Query: 2249 PCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGL 2308
PC + + +AC V+ T CH V P Y + C D C L
Sbjct: 565 QHSDPCALNPRMTRFSEEACAVL--TSPTFEACHRAVSPLPYLRNCRYDVCSCSDGRECL 622
Query: 2309 CPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAP-EGCES 2367
C A+A+Y AAC G ++ WR P C L CP Y CG C ++C SLS P E C
Sbjct: 623 CGALASYAAACAGRGVRVA-WREPGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECNE 681
Query: 2368 ACREGCVCDAGFVLS--GDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPG 2422
AC EGC C G + GD CVP QC C +DG + ++F + C C G
Sbjct: 682 ACLEGCFCPPGLYMDERGD-CVPKAQCPCYYDGEIFQPEDIF---SDHHTMCYCEDG 734
Score = 269 bits (687), Expect = 4e-71
Identities = 226/794 (28%), Positives = 325/794 (40%), Gaps = 96/794 (12%)
Query: 1249 SSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVT 1308
++ C G TFDG + F G C Y+LA C R F+++ + + NG+
Sbjct: 32 TARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRS----FSIIGD---FQNGKRVSL 84
Query: 1309 RVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLAN-GQIRASQHGSDVVIETDFGLRVA 1367
V + + L + TV D ++ + A+ G ++ G + +G
Sbjct: 85 SVYLGEFFDIHLFVNG-----TVTQGDQRVSMPYASKGLYLETEAGYYKLSGEAYGFVAR 139
Query: 1368 YDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSP 1427
D +V + Y+ + CGLCGN+N +DDF G+ + +F NSW +
Sbjct: 140 IDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQW 199
Query: 1428 CLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDC 1487
C PP S I S E++K ++ C LL S T + CH LVDP+ + C
Sbjct: 200 C--ERASPPSSSCNISSG----EMQKGLWEQ--CQLLKS-TSVFARCHPLVDPEPFVALC 250
Query: 1488 IFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSL 1547
LC G L C + Y C G + W + C CP Y C C+
Sbjct: 251 EKTLCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCAR 310
Query: 1548 GCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQ 1607
C +L CQ+ C +GC C G L + CV +C C H+G Y P T L +C
Sbjct: 311 TCQSLHINEMCQERCVDGCSCPEGQLLDEGLCVESTECPCVHSGKRY-PPGTSLSRDC-N 368
Query: 1608 QCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLP 1667
C C + +C C PG+
Sbjct: 369 TCICRNSQ-WICSNEEC-PGE--------------------------------------- 387
Query: 1668 NYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKN-QNRGN 1726
C + G H+ SFD R F F G C Y+LA C S F++ + Q +
Sbjct: 388 -----CLVTGQSHFKSFDNRYFTFSGICQYLLA-RDCQDHS------FSIVIETVQCADD 435
Query: 1727 PAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALLV 1786
R VTV G + S+ K + G V ++G LP+ D RI AS L
Sbjct: 436 RDAVCTRSVTVRLPGLHNSLVKLKHG-AGVAMDGQDVQLPLLKGDLRIQHTVTASVRLSY 494
Query: 1787 ADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSW 1846
+ LQ+ +D R+ V L Y G CGLCGN + N +D + P+G P + +G +W
Sbjct: 495 GE-DLQMDWDGRGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAW 553
Query: 1847 RAPGWDPLCWD-ECRGSCPTCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFK 1905
+ G C D + + S P R+ ++ C L S T F CH V P + +
Sbjct: 554 KLHG---DCQDLQKQHSDPCALNPRMTRFSEEA-CAVLTSPT---FEACHRAVSPLPYLR 606
Query: 1906 GCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPC 1965
C DVC R+ LC ALASY AAC GV + WR CE+ CP+ Y CG PC
Sbjct: 607 NCRYDVCSCSDGRECLCGALASYAAACAGRGVRVA-WREPGRCELNCPKGQVYLQCGTPC 665
Query: 1966 PASCPSPAPLTTP-AVCEGPCVEGCQCDAGFVL-SADRCVPLNNGCGCWANGTYHEAGSE 2023
+C S L+ P C C+EGC C G + CVP C C+ +G + +
Sbjct: 666 NLTCRS---LSYPDEECNEACLEGCFCPPGLYMDERGDCVP-KAQCPCYYDGEIFQP-ED 720
Query: 2024 FWADGTCSQWCRCG 2037
++D +C G
Sbjct: 721 IFSDHHTMCYCEDG 734
Score = 178 bits (451), Expect = 8e-44
Identities = 151/530 (28%), Positives = 218/530 (41%), Gaps = 83/530 (15%)
Query: 738 PANCPLSCPA-NSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPA 796
P L CPA N R E G C +C C CV GC+C PG V CV
Sbjct: 769 PPMVKLVCPADNLRAE--GLECTKTCQNYDL--ECMSMGCVSGCLCPPGMVRHENRCVAL 824
Query: 797 SSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGC 856
C C QG + APG+ V + CN CRD++ C
Sbjct: 825 ERCPCFHQGKEYAPGETV--------KIGCNTCV----CRDRKWNCTDHVCDA------- 865
Query: 857 YPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGS-CGQNAALPAFRVLVENEHRGSQ 915
TC G HY++FDG ++ F G C Y+LV CG N FR+LV N+
Sbjct: 866 ------TCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPG--TFRILVGNKGCSHP 917
Query: 916 TVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDF 975
+V + V + G ++ + + G+V V ++ + +V GR ++
Sbjct: 918 SVKCKKRVTILVEGGEIEL---FDGEVNVKRPMK------DETHFEVVESGRYIILLLGK 968
Query: 976 GLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQ-- 1033
L+V +D + ++ + +Y E +CGLCGNF+G +DL + + FGNSW+
Sbjct: 969 ALSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKVS 1028
Query: 1034 ---EETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRD 1090
+TR + P C + + +Q + C IL F++C+ +DP+ +
Sbjct: 1029 SQCADTRKVPLDSSPATC---HNNIMKQTMVDSSCRILT--SDVFQDCNKLVDPEPYLDV 1083
Query: 1091 CVYDRCLLP--GQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHS-------- 1140
C+YD C G CD +A YA C G V WR+ LCP SC +
Sbjct: 1084 CIYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVV-TWRTATLCPQSCEERNLRENGYEC 1142
Query: 1141 --HYEACSYGCPLSCGDLPVPGGCGSECHEGC--VCDEGFALSG--ESCLPLASCG-CVH 1193
Y +C+ C ++C P P C +C EGC C G L ++C+ C C
Sbjct: 1143 EWRYNSCAPACQVTC-QHPEPLACPVQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCEV 1201
Query: 1194 QGTYHPPGQ--TFYPG-PGCDSLCHCQEGGLVSCESSSCGPHEACQPSGG 1240
G G+ T P P +CHC L EACQ GG
Sbjct: 1202 AGRRFASGKKVTLNPSDPEHCQICHCDVVNLTC---------EACQEPGG 1242
Score = 176 bits (447), Expect = 2e-43
Identities = 144/542 (26%), Positives = 216/542 (39%), Gaps = 53/542 (9%)
Query: 2455 RCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQR----L 2510
RC G T DG +Y G CSY+LA C + FSI+ GD Q
Sbjct: 34 RCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKR----SFSII------GDFQNGKRVS 83
Query: 2511 LVTVAGQV--VSLAQGQQVTVDGEAVALPVAV-GRVRVTAEGRNMVLQTTKGLRLLFDGD 2567
L G+ + L VT + V++P A G T G + G DG
Sbjct: 84 LSVYLGEFFDIHLFVNGTVTQGDQRVSMPYASKGLYLETEAGYYKLSGEAYGFVARIDGS 143
Query: 2568 AHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEG 2627
+ + + + + CGLCGNFN DDF+ G+ S F +W + C
Sbjct: 144 GNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQWCERA 203
Query: 2628 CGPQG-CPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGD 2686
P C + E E C QL FA C ++ P + C LC G
Sbjct: 204 SPPSSSCNISSGEMQKGLW--EQC-QLLKSTSVFARCHPLVDPEPFVALCEKTLCECAGG 260
Query: 2687 KAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTG 2746
C +L Y C G+ + W S C CPA Y C C +C +L
Sbjct: 261 LECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQSLHINEM 320
Query: 2747 CTTRCFEGCECDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGL 2806
C RC +GC C + LL +G+C+ +C C H+G+ P +S L+ DC+ C C +S +
Sbjct: 321 CQERCVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYPPGTS-LSRDCN-TCICRNSQWI 378
Query: 2807 TCQAAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCP 2866
C CP G C+++ ++ +FD + Y L+ C
Sbjct: 379 -CSNEECP------------------GECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQ 419
Query: 2867 GLQNTIPWYRVVAEVQICHGKTEAVGQVHIF-----FQDGMVTLTPNKGVWVNGLRVDLP 2921
+ +V E C +AV + + +V L GV ++G V LP
Sbjct: 420 DHS-----FSIVIETVQCADDRDAVCTRSVTVRLPGLHNSLVKLKHGAGVAMDGQDVQLP 474
Query: 2922 AEKLASVSVSRTPDGSLLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTN 2981
K + + T S+ + +Q+ G++ V +S +AGK CG CGN++G+Q +
Sbjct: 475 LLK-GDLRIQHTVTASVRLSYGEDLQMDWDGRGRLLVKLSPVYAGKTCGLCGNYNGNQGD 533
Query: 2982 DW 2983
D+
Sbjct: 534 DF 535
Score = 167 bits (423), Expect = 1e-40
Identities = 139/506 (27%), Positives = 202/506 (39%), Gaps = 75/506 (14%)
Query: 1166 CHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCE 1225
C GC+C G C+ L C C HQG + PG+T G C++ C C++
Sbjct: 804 CVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGETVKIG--CNT-CVCRD------R 854
Query: 1226 SSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQT-CGT 1284
+C H V +TC G HY TFDG ++ F G C YVL Q CG+
Sbjct: 855 KWNCTDH--------------VCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGS 900
Query: 1285 RPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLAN 1344
PG F +L N + V + +T+ V + L + V++K P+
Sbjct: 901 NPGT--FRILVGNKGCSHPSVKCKKRVTILVEGGEIELFDGE-------VNVKRPMK-DE 950
Query: 1345 GQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKP 1404
+ G +++ L V +D + V + Y +++CGLCGN++G +D
Sbjct: 951 THFEVVESGRYIILLLGKALSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSS 1010
Query: 1405 NGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLL 1464
N + +FGNSW+ S C P S C + K+ + C +L
Sbjct: 1011 NLQVEEDPVDFGNSWK---VSSQCADTRKVPLDSSPA----TCHNNIMKQTMVDSSCRIL 1063
Query: 1465 SSPTGPLSSCHKLVDPQGPLKDCIFDLCL--GGGNLSILCSNIHAYVSACQAAGGHVEPW 1522
+S C+KLVDP+ L CI+D C G+ + C I AY C A G V W
Sbjct: 1064 TSDV--FQDCNKLVDPEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVC-AQHGKVVTW 1120
Query: 1523 RTETFCPMECPPNS----------HYELCADTCSLGC---SALSAPPQCQDGCAEGCQCD 1569
RT T CP C + Y CA C + C L+ P QC +GC C
Sbjct: 1121 RTATLCPQSCEERNLRENGYECEWRYNSCAPACQVTCQHPEPLACPVQCVEGCHAHCPPG 1180
Query: 1570 SGFLYNGQACVPIQQCG-CYHNGVYYEPEQTVLI-----DNCRQQCTCHAGKGMVCQEHS 1623
Q CV + C C G + + V + ++C Q C C + C
Sbjct: 1181 KILDELLQTCVDPEDCPVCEVAGRRFASGKKVTLNPSDPEHC-QICHCDV-VNLTC---- 1234
Query: 1624 CKPGQVCQPSGGILSCVTKDPCHGVT 1649
+ CQ GG++ T P T
Sbjct: 1235 ----EACQEPGGLVVPPTDAPVSPTT 1256
Score = 153 bits (386), Expect = 3e-36
Identities = 149/550 (27%), Positives = 210/550 (38%), Gaps = 73/550 (13%)
Query: 2299 CQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPS 2358
C + G PG L P + L RP L CPA + G C +C +
Sbjct: 738 CTMSGVPGSLLPDAVLSSPLSHRSKRSLS--CRPPMVKLVCPA-DNLRAEGLECTKTCQN 794
Query: 2359 LSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCE 2418
E C GC+C G V + CV + +C C H G+ Y GE G C C
Sbjct: 795 YDL-ECMSMGCVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGETVKIG--CNT-CV 850
Query: 2419 CGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSC 2478
C C H C AT C G HY+T DG Y G C
Sbjct: 851 CR-------DRKWNCTDH----------VCDAT----CSTIGMAHYLTFDGLKYLFPGEC 889
Query: 2479 SYVLAQ-VCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVSLAQGQQVTV-DGEA-VA 2535
YVL Q C PG F I++ V +V L +G ++ + DGE V
Sbjct: 890 QYVLVQDYCGSNPGT--FRILVGNKGCSHPS---VKCKKRVTILVEGGEIELFDGEVNVK 944
Query: 2536 LPVA-VGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWS 2594
P+ V GR ++L K L +++D + + + ++ ++CGLCGNF+G +
Sbjct: 945 RPMKDETHFEVVESGRYIILLLGKALSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQN 1004
Query: 2595 DDFVLPNGSAASSVETFGAAWRAPGSSKGCGE------GCGPQGCPVCLAEETAPYESNE 2648
+D N FG +W+ S C + P C + ++T +
Sbjct: 1005 NDLTSSNLQVEEDPVDFGNSWKV---SSQCADTRKVPLDSSPATCHNNIMKQTM---VDS 1058
Query: 2649 ACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQK--GDKAFLCRSLAAYTAACQAAGV 2706
+C L + F C ++ P Y C+YD C+ + GD A C ++AAY C G
Sbjct: 1059 SCRILTS--DVFQDCNKLVDPEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVCAQHGK 1116
Query: 2707 AVKPWRTDSFCPLHCPAHS----------HYSICTRTCQGSCAALSGLTGCTTRCFEGC- 2755
V WRT + CP C + Y+ C CQ +C L C +C EGC
Sbjct: 1117 VV-TWRTATLCPQSCEERNLRENGYECEWRYNSCAPACQVTCQHPEPL-ACPVQCVEGCH 1174
Query: 2756 -ECDDRFLLSQ--GVCIPVQDCG-CTHNGRYLPVNSSL-LTSDCSERCSCSSSS--GLTC 2808
C +L + C+ +DC C GR + L E C LTC
Sbjct: 1175 AHCPPGKILDELLQTCVDPEDCPVCEVAGRRFASGKKVTLNPSDPEHCQICHCDVVNLTC 1234
Query: 2809 QAAGCPPGRV 2818
+A P G V
Sbjct: 1235 EACQEPGGLV 1244
Score = 135 bits (340), Expect = 6e-31
Identities = 115/398 (28%), Positives = 169/398 (42%), Gaps = 43/398 (10%)
Query: 470 AVCRAQGDPHYTTFDGRRYDMMGTCSYTMVE-LCSEDDTLPAFSVEAKNEHRGSRRVSYV 528
A C G HY TFDG +Y G C Y +V+ C + F + N+ V
Sbjct: 865 ATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPG--TFRILVGNKGCSHPSVKCK 922
Query: 529 GLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVT 588
VT+ + L GEV + P+ E V +SG ++ L L V
Sbjct: 923 KRVTILVEGGEIELFDGEVNV--------KRPMK-DETHFEVVESGRYIILLLGKALSVV 973
Query: 589 YDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYL 648
+D +++ L +Q++VCGLCGN++G +D + + + D V+F +SWK+
Sbjct: 974 WDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKVSS---Q 1030
Query: 649 CEDGCQ---NNCPA-CTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDL 704
C D + ++ PA C + D C +LT F C+ +DP P+L+ C+YD
Sbjct: 1031 CADTRKVPLDSSPATCHNNIMKQTMVDSSCRILT--SDVFQDCNKLVDPEPYLDVCIYDT 1088
Query: 705 CVVG--GERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSCPANS----------RYE 752
C G+ C ++AYA C + G V WR+ CP SC + RY
Sbjct: 1089 CSCESIGDCACFCDTIAAYAHVCAQHG-KVVTWRTATLCPQSCEERNLRENGYECEWRYN 1147
Query: 753 LCGPACPTSCNGAAAPSNCSGRPCVEGC--VCLPGFVASG--GACVPASSCG-CTFQGLQ 807
C PAC +C P C + CVEGC C PG + CV C C G +
Sbjct: 1148 SCAPACQVTCQ-HPEPLACPVQ-CVEGCHAHCPPGKILDELLQTCVDPEDCPVCEVAGRR 1205
Query: 808 LAPGQEVWADELCQRRC-TCNGATHQVTCRDKQSCPAG 844
A G++V + C C+ +TC Q P G
Sbjct: 1206 FASGKKVTLNPSDPEHCQICHCDVVNLTCEACQE-PGG 1242
Score = 132 bits (332), Expect = 5e-30
Identities = 118/462 (25%), Positives = 184/462 (39%), Gaps = 60/462 (12%)
Query: 2397 DGRYYPLGEVFYPGPECERRCECGPGGH-------VTCQEGA--ACGPHEECRLEDGVQA 2447
DG G+V+ +C C P G V C G +C + +
Sbjct: 1883 DGNEKRPGDVWTLPDQCHT-VTCQPDGQTLLKSHRVNCDRGLRPSCPNSQSPVKVEETCG 1941
Query: 2448 CHATGCGRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAA--- 2504
C T C + H +T DG+ + L GSCSYVL Q ++D ++L A
Sbjct: 1942 CRWTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQ-----NKEQDLEVILHNGACSPG 1996
Query: 2505 ---GDLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLR 2561
G ++ + V + V L +VTV+G V++P G + V G M L
Sbjct: 1997 ARQGCMKSIEVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLG 2056
Query: 2562 LLF----DGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRA 2617
+F + L P F + GLCG + N ++DF+L +G+ + +T W
Sbjct: 2057 HIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEW-- 2114
Query: 2618 PGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCV 2677
+ + G+ C P + EE + C L P FA C VL+P+ ++ C
Sbjct: 2115 --TVQRPGQTCQP------ILEEQCLVPDSSHCQVLLLPL--FAECHKVLAPATFYAICQ 2164
Query: 2678 YDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGS 2737
D C Q+ +C +A+Y C+ GV V WRT FC + CP Y+ C C
Sbjct: 2165 QDSCHQEQ----VCEVIASYAHLCRTNGVCV-DWRTPDFCAMSCPPSLVYNHCEHGCPRH 2219
Query: 2738 CAALSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQDC-------GCTHNGRYLPVNSSLL 2790
C ++ C EGC C ++ +G C+P + C G H + + +
Sbjct: 2220 CD--GNVSSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQF----LEAWVP 2273
Query: 2791 TSDCSERCSCSSSSGLTCQAAGCPPGR-----VCEVKAEARN 2827
+ C+C S + C CP + +CEV +N
Sbjct: 2274 DHQPCQICTCLSGRKVNCTTQPCPTAKAPTCGLCEVARLRQN 2315
Score = 129 bits (324), Expect = 4e-29
Identities = 117/440 (26%), Positives = 176/440 (40%), Gaps = 42/440 (9%)
Query: 805 GLQLAPGQEVWA--DELCQRRCTCNGAT----HQVTCRD--KQSCPAGERCSVQNGLLGC 856
G + PG +VW D+ C +G T H+V C + SCP + GC
Sbjct: 1884 GNEKRPG-DVWTLPDQCHTVTCQPDGQTLLKSHRVNCDRGLRPSCPNSQSPVKVEETCGC 1942
Query: 857 YPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQT 916
C GS H V+FDG+ F G+C+Y+L + Q+ + +L
Sbjct: 1943 RWTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQDLEV----ILHNGACSPGAR 1998
Query: 917 VSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFG 976
+++ V+ + V + + +V V+ L +P+ + +V V+ V G
Sbjct: 1999 QGCMKSIEVKHSALSVELHSDM--EVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLG 2056
Query: 977 --LTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQE 1034
T T N P ++A GLCG + + A+D LR G + W
Sbjct: 2057 HIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTV 2116
Query: 1035 ETRPG--CGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCV 1092
+ RPG C C DS + C +L P F ECH L P C
Sbjct: 2117 Q-RPGQTCQPILEEQCLVPDS---------SHCQVLLLPL--FAECHKVLAPATFYAICQ 2164
Query: 1093 YDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLS 1152
D C +C+ +A+YA C+ G V WR+ + C +SCPP Y C +GCP
Sbjct: 2165 QDSC----HQEQVCEVIASYAHLCRTNGVCVD-WRTPDFCAMSCPPSLVYNHCEHGCPRH 2219
Query: 1153 C-GDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASC-GCV-HQGTYHPPGQTFYPGPG 1209
C G++ CG EGC C + SC+P +C C+ G H + + P
Sbjct: 2220 CDGNV---SSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPDHQ 2276
Query: 1210 CDSLCHCQEGGLVSCESSSC 1229
+C C G V+C + C
Sbjct: 2277 PCQICTCLSGRKVNCTTQPC 2296
Score = 120 bits (302), Expect = 2e-26
Identities = 115/425 (27%), Positives = 170/425 (40%), Gaps = 44/425 (10%)
Query: 433 GRTVLSPVEPSCE-GMQ--CAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYD 489
G+T+L +C+ G++ C Q V GC VC H TFDG+ +
Sbjct: 1908 GQTLLKSHRVNCDRGLRPSCPNSQSPVKVEETCGCRWTCPCVCTGSSTRHIVTFDGQNFK 1967
Query: 490 MMGTCSYTMVELCSEDDTLPAFSVEAKNEHRGS----RRVSYVGLVTVRAYSHSVSLTRG 545
+ G+CSY + + +D + H G+ R + + V+ + SV L
Sbjct: 1968 LTGSCSYVLFQNKEQDLEVIL--------HNGACSPGARQGCMKSIEVKHSALSVELHSD 2019
Query: 546 EVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVTY---DWDCQLALSLPAR 602
V V+ + +P + VY + V G + T+ + + QL LS P
Sbjct: 2020 ME--VTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLGHIFTFTPQNNEFQLQLS-PKT 2076
Query: 603 FQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTP 662
F + GLCG + + A+DF+ DG + D W + C+ + C
Sbjct: 2077 FASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQRPGQTCQPILEEQCLVPDS 2136
Query: 663 GQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYA 722
Q +L L FA CH L P F C D C + +C +++YA
Sbjct: 2137 SHCQV--------LLLPL---FAECHKVLAPATFYAICQQDSC----HQEQVCEVIASYA 2181
Query: 723 QACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVC 782
C G+ V DWR+P C +SCP + Y C CP C+G S+C P EGC C
Sbjct: 2182 HLCRTNGVCV-DWRTPDFCAMSCPPSLVYNHCEHGCPRHCDGNV--SSCGDHPS-EGCFC 2237
Query: 783 LPGFVASGGACVPASSC-GCTFQGLQLAPGQEVWA-DELCQRRCTCNGATHQVTCRDKQS 840
P V G+CVP +C C + E W D + CTC +V C Q
Sbjct: 2238 PPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPDHQPCQICTCLSG-RKVNC-TTQP 2295
Query: 841 CPAGE 845
CP +
Sbjct: 2296 CPTAK 2300
Score = 115 bits (288), Expect = 7e-25
Identities = 124/500 (24%), Positives = 180/500 (36%), Gaps = 85/500 (17%)
Query: 1961 CGPP-----CPASCPSPAPLTTPAVCEG--------PCVEGCQCDAGFVLSADRCVPLNN 2007
C PP CPA L C+ CV GC C G V +RCV L
Sbjct: 767 CRPPMVKLVCPADNLRAEGLECTKTCQNYDLECMSMGCVSGCLCPPGMVRHENRCVALER 826
Query: 2008 GCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQ 2067
C C +H+ G E+ T C + VC + H C
Sbjct: 827 -CPC-----FHQ-GKEYAPGETVKIGCN------TCVCRDRKWNCTD---------HVCD 864
Query: 2068 PVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQA 2127
A C G HY+T DG ++ F G C+Y+L G G F + V N+ +
Sbjct: 865 ----ATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPG--TFRILVGNKGCSHPS 918
Query: 2128 VSYTRSVTLQIYNHSLTLSARWPRKLQVDG-VFVALPFQLDSLLHAHLSGADVVVTTTSG 2186
V + VT+ + + L DG V V P + ++ SG +++
Sbjct: 919 VKCKKRVTILVEGGEIEL---------FDGEVNVKRPMKDETHFEVVESGRYIILLLGKA 969
Query: 2187 LSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKA----VGGKPA----GWQVGG 2238
LS+ +D + + + Y +CGLCGN++ +DL + V P W+V
Sbjct: 970 LSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKV-- 1027
Query: 2239 AQGCGECVSKP---CPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCL 2295
+ C + P P+ C + +C ++ T C+ LV P Y C+
Sbjct: 1028 SSQCADTRKVPLDSSPATCHNNIMKQTMVDSSCRIL--TSDVFQDCNKLVDPEPYLDVCI 1085
Query: 2296 LDACQVQ--GHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHS---------- 2343
D C + G C +A Y C G ++ WR CP C +
Sbjct: 1086 YDTCSCESIGDCACFCDTIAAYAHVCAQHG-KVVTWRTATLCPQSCEERNLRENGYECEW 1144
Query: 2344 HYELCGDSCPVSCPSLSAPEGCESACREGC--VCDAGFVLSG--DTCVPVGQCG-CLHDG 2398
Y C +C V+C P C C EGC C G +L TCV C C G
Sbjct: 1145 RYNSCAPACQVTCQH-PEPLACPVQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCEVAG 1203
Query: 2399 RYYPLGEVFYPGPECERRCE 2418
R + G+ P C+
Sbjct: 1204 RRFASGKKVTLNPSDPEHCQ 1223
Score = 108 bits (271), Expect = 6e-23
Identities = 101/405 (24%), Positives = 162/405 (40%), Gaps = 47/405 (11%)
Query: 2065 GCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG 2124
GC+ C H VT DG F G+C Y+L E + +
Sbjct: 1941 GCRWTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQ-------NKEQDLEVILHNGAC 1993
Query: 2125 SQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTT 2184
S ++++ + +L++ ++ V+G V++P+ + + ++ GA +
Sbjct: 1994 SPGARQGCMKSIEVKHSALSVELHSDMEVTVNGRLVSVPY-VGGNMEVNVYGAIMHEVRF 2052
Query: 2185 SGLSLAF----DGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGK-PAGWQVGGA 2239
+ L F + F P +A+ GLCG +++ A+D G W+
Sbjct: 2053 NHLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQ 2112
Query: 2240 QGCGECVSKPCPSPCTPEQQESFGGPDA--CGVISATDGPL-APCHGLVPPAQYFQGCLL 2296
+ V +P + C P +E PD+ C V+ PL A CH ++ PA ++ C
Sbjct: 2113 EWT---VQRPGQT-CQPILEEQCLVPDSSHCQVLLL---PLFAECHKVLAPATFYAICQQ 2165
Query: 2297 DACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSC 2356
D+C H +C +A+Y C+ G + +WR PDFC + CP Y C CP C
Sbjct: 2166 DSC----HQEQVCEVIASYAHLCRTNGVCV-DWRTPDFCAMSCPPSLVYNHCEHGCPRHC 2220
Query: 2357 PSLSAPEGCESAC----REGCVCDAGFVLSGDTCVPVGQC-GCL-HDGRYYPLGEVFYPG 2410
+G S+C EGC C V+ +CVP C C+ DG + E + P
Sbjct: 2221 ------DGNVSSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPD 2274
Query: 2411 PECERRCECGPGGHVTC-------QEGAACGPHEECRLEDGVQAC 2448
+ + C C G V C + CG E RL C
Sbjct: 2275 HQPCQICTCLSGRKVNCTTQPCPTAKAPTCGLCEVARLRQNADQC 2319
Score = 105 bits (262), Expect = 7e-22
Identities = 127/503 (25%), Positives = 183/503 (36%), Gaps = 97/503 (19%)
Query: 1193 HQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESS--------SCGPHEACQPSGGSLGC 1244
H T P GQT +C G SC +S +CG C C
Sbjct: 1900 HTVTCQPDGQTLLKS----HRVNCDRGLRPSCPNSQSPVKVEETCGCRWTCP-------C 1948
Query: 1245 VAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGR 1304
V GSST H TFDG+ F G+C YVL Q L +L R
Sbjct: 1949 VCTGSST------RHIVTFDGQNFKLTGSCSYVLFQ--NKEQDLE--VILHNGACSPGAR 1998
Query: 1305 VSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGL 1364
+ I V+ + ++ L +VTVNG + +P V G + + +G+ ++ E F
Sbjct: 1999 QGCMKSIEVKHSALSVELHS-DMEVTVNGRLVSVPYV--GGNMEVNVYGA-IMHEVRFN- 2053
Query: 1365 RVAYDLVYYVRVTVPGNYYQ----------QMCGLCGNYNGDPKDDFQKPNGSQAGNANE 1414
L + T N +Q + GLCG + + +DF +G+ +
Sbjct: 2054 ----HLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKT 2109
Query: 1415 FGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSC 1474
W P C P E C+ C +L P + C
Sbjct: 2110 LVQEWTVQRPGQTCQPIL-----EEQCL------------VPDSSHCQVLLLPL--FAEC 2150
Query: 1475 HKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPP 1534
HK++ P C D C + +C I +Y C+ G V+ WRT FC M CPP
Sbjct: 2151 HKVLAPATFYAICQQDSC----HQEQVCEVIASYAHLCRTNGVCVD-WRTPDFCAMSCPP 2205
Query: 1535 NSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQC-GCY-HNGV 1592
+ Y C C C + C D +EGC C + +CVP + C C +GV
Sbjct: 2206 SLVYNHCEHGCPRHCDGNVS--SCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGV 2263
Query: 1593 YYEPEQTVLIDN--CRQQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTC 1650
++ + + D+ C Q CTC +G+ + C C K P TC
Sbjct: 2264 QHQFLEAWVPDHQPC-QICTCLSGRKVNCTTQPCP--------------TAKAP----TC 2304
Query: 1651 RPQETCKEQGGQGVCLPNYEATC 1673
E + + C P YE C
Sbjct: 2305 GLCEVARLRQNADQCCPEYECVC 2327
Score = 91.3 bits (225), Expect = 1e-17
Identities = 114/470 (24%), Positives = 166/470 (35%), Gaps = 77/470 (16%)
Query: 1643 DPCHGVTCRP--QETCK------EQGGQGVCLPN------YEATCWL-WGDP-------- 1679
D CH VTC+P Q K ++G + C PN E TC W P
Sbjct: 1897 DQCHTVTCQPDGQTLLKSHRVNCDRGLRPSC-PNSQSPVKVEETCGCRWTCPCVCTGSST 1955
Query: 1680 -HYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVA 1738
H +FDG+ F G+C+YVL Q L + ++ + V
Sbjct: 1956 RHIVTFDGQNFKLTGSCSYVLFQN-----KEQDLE--VILHNGACSPGARQGCMKSIEVK 2008
Query: 1739 ALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYD-W 1797
++ +H D + V VNG L ++P + ++V + G ++
Sbjct: 2009 HSALSVELHSD----MEVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLGHIFTFTPQ 2064
Query: 1798 NWRVDVTL-PSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCW 1856
N + L P ++ GLCG D N ND + +GT+ W C
Sbjct: 2065 NNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQRPGQTCQ 2124
Query: 1857 DECRGSCPTCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDVCMGGG 1916
C + P F CH + P +F+ C D C
Sbjct: 2125 PILEEQCLVPDSSHCQVLLLP------------LFAECHKVLAPATFYAICQQDSC---- 2168
Query: 1917 DRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLT 1976
++ +C+ +ASY C+ GV + DWR C ++CP + Y C CP C
Sbjct: 2169 HQEQVCEVIASYAHLCRTNGVCV-DWRTPDFCAMSCPPSLVYNHCEHGCPRHCDG----- 2222
Query: 1977 TPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGC-WANGTYHEAGSEFWADGTCSQWCR 2035
+ C EGC C V+ CVP C +G H+ + D Q C
Sbjct: 2223 NVSSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPDHQPCQICT 2282
Query: 2036 CGPGGGSLVCT--------PASCGLGEVCGL-------LPSGQHGCQPVS 2070
C G + CT +CGL EV L P + C PVS
Sbjct: 2283 C-LSGRKVNCTTQPCPTAKAPTCGLCEVARLRQNADQCCPEYECVCDPVS 2331
Score = 35.4 bits (80), Expect = 0.86
Identities = 34/121 (28%), Positives = 50/121 (41%), Gaps = 23/121 (19%)
Query: 1129 EELCPLSCPPHS-----HYEACS-YGCPLSCGDLPVP---GGCGSECHEGCVCDEGFALS 1179
+ + P SCPPH + C Y C +C + V G S C C +
Sbjct: 2368 KRVSPPSCPPHRLPTLRKTQCCDEYECACNCVNSTVSCPLGYLASTATNDCGC------T 2421
Query: 1180 GESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHC--QEGGLVSCESSSCGPHEACQP 1237
+CLP CVH+ T +P GQ + GCD +C C E ++ + C + C+
Sbjct: 2422 TTTCLP--DKVCVHRSTIYPVGQ--FWEEGCD-VCTCTDMEDAVMGLRVAQCS-QKPCED 2475
Query: 1238 S 1238
S
Sbjct: 2476 S 2476
Score = 34.7 bits (78), Expect = 1.5
Identities = 23/71 (32%), Positives = 33/71 (46%), Gaps = 13/71 (18%)
Query: 1568 CDSGFLYNGQ--ACVPIQQC----GCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMV--- 1618
C SGF + + AC P +C C NG P +TV+ID C C C G++
Sbjct: 2557 CPSGFQLSCKTSACCPSCRCERMEACMLNGTVIGPGKTVMIDVC-TTCRCMVQVGVISGF 2615
Query: 1619 ---CQEHSCKP 1626
C++ +C P
Sbjct: 2616 KLECRKTTCNP 2626
Score = 32.0 bits (71), Expect = 9.5
Identities = 49/178 (27%), Positives = 62/178 (34%), Gaps = 40/178 (22%)
Query: 2294 CLLDACQV-QGHPGGLCPAVATYVAACQAAGAQLGEWRRPDF-CPLQCPAHSHYELCGDS 2351
CL AC+V G P G ++ ++ G+Q W P+ C + E+
Sbjct: 2494 CLPSACEVVTGSPRG------DSQSSWKSVGSQ---WASPENPCLINECVRVKEEVFIQQ 2544
Query: 2352 CPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGP 2411
VSCP L P VC +GF LS T C C G V PG
Sbjct: 2545 RNVSCPQLEVP-----------VCPSGFQLSCKTSACCPSCRCERMEACMLNGTVIGPGK 2593
Query: 2412 ----ECERRCECGPGGHVTCQEGAACGPHEECRLED------GVQACHATG--CGRCL 2457
+ C C Q G G ECR G + + TG CGRCL
Sbjct: 2594 TVMIDVCTTCRC------MVQVGVISGFKLECRKTTCNPCPLGYKEENNTGECCGRCL 2645
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 345 bits (884), Expect = 5e-94
Identities = 338/1286 (26%), Positives = 504/1286 (39%), Gaps = 201/1286 (15%)
Query: 864 CQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAV 923
C G+ HY +FDG F F G C Y C + F V ++ ++ + ++
Sbjct: 37 CSTWGNFHYKTFDGDVFRFPGLCDYNFASDC--RGSYKEFAVHLKRGPGQAEAPAGVESI 94
Query: 924 RVEARGVKVAVRREYPGQVLVDDVLQ---YLP---FQAADGQVQVFRQGRDAVVRTDFGL 977
+ + + + R VL V+ Y P + +D +V+ + GL
Sbjct: 95 LLTIKDDTIYLTRHLA--VLNGAVVSTPHYSPGLLIEKSDAYTKVYSRA---------GL 143
Query: 978 TVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETR 1037
T+ ++ + ++ + + CGLCG++NG + L G + L FGN Q+ +
Sbjct: 144 TLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFL-SDGVLFSPLEFGNM-QKINQ 201
Query: 1038 PGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCL 1097
P +P + + A + + EC L + F +C + + +R C DRC
Sbjct: 202 PDVVCEDPEE----EVAPASCSEHRAECERLLTAEA-FADCQDLVPLEPYLRACQQDRCR 256
Query: 1098 LPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLP 1157
PG +C +A ++ C AG WR+ LCP +CP + Y C +C L
Sbjct: 257 CPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATLCPKTCPGNLVYLESGSPCMDTCSHLE 316
Query: 1158 VPGGCGSECHEGCVCDEGFA---LSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLC 1214
V C +GC C EG + C+P++ C C G + PGQ C+ C
Sbjct: 317 VSSLCEEHRMDGCFCPEGTVYDDIGDSGCVPVSQCHCRLHGHLYTPGQEI--TNDCEQ-C 373
Query: 1215 HCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTC 1274
C G V C+ C TC G H TTFDG+ + F G C
Sbjct: 374 VCNAGRWV-CKDLPC-------------------PGTCALEGGSHITTFDGKTYTFHGDC 413
Query: 1275 VYVLAQTCGTRPGLHR--FAVLQENVAWG--NGRVSVTRVITVQVANFTLRLEQRQWKVT 1330
YVLA+ G H +A+L E G + + + V+ + + + + V
Sbjct: 414 YYVLAK------GDHNDSYALLGELAPCGSTDKQTCLKTVVLLADKKKNVVVFKSDGSVL 467
Query: 1331 VNGVDMKLPVVLANGQI-RASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGL 1389
+N + + LP V A+ + R S + V + L+V V + VT+ Q+ GL
Sbjct: 468 LNELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGL 527
Query: 1390 CGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPP 1449
CGN+NG DDF+ +G F N+W+ S C D + C
Sbjct: 528 CGNFNGLEGDDFKTASGLVEATGAGFANTWK---AQSSC-------HDKLDWL-DDPCSL 576
Query: 1450 ELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYV 1509
+E E +C LL P CH VDP K C +D C N LC+ + +Y
Sbjct: 577 NIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYA 636
Query: 1510 SACQAAGGHVEPWRTETFCPME---CPPNSHYELCADTCSLGCSALS-APPQCQDGCA-- 1563
AC A G + WR E C + CP + + TC C +LS A C +G A
Sbjct: 637 RACTAKGVMLWGWR-EHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPV 695
Query: 1564 EGCQC-DSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAG-------- 1614
+GC C D FL CVP+ +C CYH G+Y E V+ ++C C G
Sbjct: 696 DGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVV--RQEERCVCRDGRLHCRQIR 753
Query: 1615 --------------------------KGMVCQ-------EHSCKPGQVCQPSG----GIL 1637
+ + CQ C G VC P G G
Sbjct: 754 LIGQSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVC-PDGLMDDGRG 812
Query: 1638 SCVTKDPC---HG-----------VTCRPQETCKEQGGQGVCLPNY-EATCWLWGDPHYH 1682
CV + C H V C TC + G+ VC TC ++G HY
Sbjct: 813 GCVVEKECPCVHNNDLYSSGAKIKVDC---NTCTCKRGRWVCTQAVCHGTCSIYGSGHYI 869
Query: 1683 SFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGT 1742
+FDG+ +DF G C+YV C S+ G F++ T+N G V+ + + + T
Sbjct: 870 TFDGKYYDFDGHCSYVAVQDYCGQNSSLG--SFSIITENVPCGTTGVTCSKAIKIFMGRT 927
Query: 1743 NIS--------IHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVS 1794
+ I +DE V V G+ V + ++ G+ V
Sbjct: 928 ELKLEDKHRVVIQRDEGHHVAYTTREV----------GQYLVVESST--------GIIVI 969
Query: 1795 YDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPL 1854
+D V + L SY G VCGLCGN D NND + + S +G SW+ P
Sbjct: 970 WDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEA---PT 1026
Query: 1855 CWDECRGSCPTCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDVCM- 1913
C D P C + + C L S F+ CH+ V P+ F++ CV D C
Sbjct: 1027 CPDVSTNPEP-CSLNPHRRSWAEKQCSILKSSV---FSICHSKVDPKPFYEACVHDSCSC 1082
Query: 1914 -GGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENS-------HYEVCGPPC 1965
GGD + C A+ASY C G + WR C I C + HYE CG
Sbjct: 1083 DTGGDCECFCSAVASYAQECTKEGACV-FWRTPDLCPIFCDYYNPPHECEWHYEPCGNRS 1141
Query: 1966 PASCPSPAPL---TTPAVCEGPCVEGCQCDAG-FVLSADRCVPLNNGCGCWANGTYHEAG 2021
+C + + + + EG C C D + +CV + CGC+ T++ G
Sbjct: 1142 FETCRTINGIHSNISVSYLEG-CYPRCPKDRPIYEEDLKKCVTADK-CGCYVEDTHYPPG 1199
Query: 2022 SEFWADGTCSQWCRCGPGGGSLVCTP 2047
+ + TC C C +VC P
Sbjct: 1200 ASVPTEETCKS-CVC-TNSSQVVCRP 1223
Score = 304 bits (779), Expect = 8e-82
Identities = 312/1267 (24%), Positives = 481/1267 (37%), Gaps = 211/1267 (16%)
Query: 1673 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYV 1732
C WG+ HY +FDG F F G C+Y A+ C G + F V K A + V
Sbjct: 37 CSTWGNFHYKTFDGDVFRFPGLCDYNFASD-CRGSYKE----FAVHLKRGPGQAEAPAGV 91
Query: 1733 RVVTVAALGTNISIHKDEIGKVR--VCVNGVLTALPVSVADGRISVAQGASKALLVADFG 1790
+ ++I D I R +NG + + P I + +K A G
Sbjct: 92 ESIL-------LTIKDDTIYLTRHLAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRA--G 142
Query: 1791 LQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPG 1850
L + ++ + + L + + CGLCG+ + + + +G L + +G +
Sbjct: 143 LTLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLE-FGNMQKINQ 201
Query: 1851 WDPLCWDECRGSCP-TCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVL 1909
D +C D P +C E R E C L T F C VP E + + C
Sbjct: 202 PDVVCEDPEEEVAPASCSEHRAE-------CERLL--TAEAFADCQDLVPLEPYLRACQQ 252
Query: 1910 DVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASC 1969
D C G +C +A + C AG +WR C TCP N Y G PC +C
Sbjct: 253 DRCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATLCPKTCPGNLVYLESGSPCMDTC 312
Query: 1970 PSPAPLTTPAVCEGPCVEGCQCDAGFV---LSADRCVPLNNGCGCWANGTYHEAGSEFWA 2026
+ L ++CE ++GC C G V + CVP++ C C +G + G E
Sbjct: 313 ---SHLEVSSLCEEHRMDGCFCPEGTVYDDIGDSGCVPVSQ-CHCRLHGHLYTPGQEITN 368
Query: 2027 DGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLD 2086
D C Q C C G VC C C G H T D
Sbjct: 369 D--CEQ-CVC--NAGRWVCKDLPC--------------------PGTCALEGGSHITTFD 403
Query: 2087 GHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGS-QAVSYTRSVTLQIYNHSLTL 2145
G + F G C Y+L+ H +++ + GS + ++V L +
Sbjct: 404 GKTYTFHGDCYYVLAKGDHN-----DSYALLGELAPCGSTDKQTCLKTVVLLADKKKNVV 458
Query: 2146 SARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAY 2205
+ + ++ + V LP S S ++V+ G+ L ++L V
Sbjct: 459 VFKSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQ 518
Query: 2206 AA--SLCGLCGNYNQDPADDLKAVGGKPAGWQVGGA---QGCGECVSKP--CPSPCTPEQ 2258
A+ + GLCGN+N DD K G G A + C K PC+
Sbjct: 519 ASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKLDWLDDPCSLNI 578
Query: 2259 QESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAA 2318
+ + C ++ T+ P CH V PA+Y++ C D C Q + LC A+++Y A
Sbjct: 579 ESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARA 638
Query: 2319 CQAAGAQLGEWRRPDFCPL---QCPAHSHYELCGDSCPVSCPSLSAPEGCESACRE---- 2371
C A G L WR C CP + +C +C SLS +S C E
Sbjct: 639 CTAKGVMLWGWRE-HVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSE---ADSHCLEGFAP 694
Query: 2372 --GCVC-DAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPG------ 2422
GC C D F+ CVP+ +C C H G Y G+V E RC C G
Sbjct: 695 VDGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVV---RQEERCVCRDGRLHCRQ 751
Query: 2423 ----------------------------GHVTCQEGAACGPHEEC---------RLEDGV 2445
++CQ AA H EC ++DG
Sbjct: 752 IRLIGQSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDGLMDDGR 811
Query: 2446 QAC--------------HATG------CGRCLANGGI------------------HYITL 2467
C +++G C C G HYIT
Sbjct: 812 GGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYGSGHYITF 871
Query: 2468 DGRVYDLHGSCSYVLAQ-VCHPKPGDEDFSIVLEKNAAGDL-----QRLLVTVAGQVVSL 2521
DG+ YD G CSYV Q C FSI+ E G + + + + + L
Sbjct: 872 DGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKL 931
Query: 2522 AQGQQVTV---DGEAVALPVAVGRVRVTAE-GRNMVLQTTKGLRLLFDGDAHLLMSIPSP 2577
+V + +G VA T E G+ +V++++ G+ +++D + + +
Sbjct: 932 EDKHRVVIQRDEGHHVAY--------TTREVGQYLVVESSTGIIVIWDKRTTVFIKLAPS 983
Query: 2578 FRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCL 2637
++G +CGLCGNF+ ++DF + SS FG +W+ + P C
Sbjct: 984 YKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTCPDVSTNPEP-----CS 1038
Query: 2638 AEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCA--QKGDKAFLCRSLA 2695
+ + C L++ F+ C + + P ++ CV+D C+ GD C ++A
Sbjct: 1039 LNPHRRSWAEKQCSILKS--SVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVA 1096
Query: 2696 AYTAACQAAGVAVKPWRTDSFCPLHC----PAHS---HYSICTRTCQGSCAALSGL-TGC 2747
+Y C G V WRT CP+ C P H HY C +C ++G+ +
Sbjct: 1097 SYAQECTKEGACVF-WRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNI 1155
Query: 2748 TTRCFEGC--EC-DDRFLLSQGV--CIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSS 2802
+ EGC C DR + + + C+ CGC + P +S+ T + + C C++
Sbjct: 1156 SVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGASVPTEETCKSCVCTN 1215
Query: 2803 SSGLTCQ 2809
SS + C+
Sbjct: 1216 SSQVVCR 1222
Score = 287 bits (734), Expect = 1e-76
Identities = 269/1033 (26%), Positives = 403/1033 (39%), Gaps = 189/1033 (18%)
Query: 2074 CQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRS 2133
C WG+ HY T DG F F G C+Y ++ C G + F V + ++A + S
Sbjct: 37 CSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRG---SYKEFAVHLKRGPGQAEAPAGVES 93
Query: 2134 VTLQIYNHSLTLSARWPRKLQV-DGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFD 2192
+ L I + ++ L+ R L V +G V+ P LL S A V + +GL+L ++
Sbjct: 94 ILLTIKDDTIYLT----RHLAVLNGAVVSTPHYSPGLL-IEKSDAYTKVYSRAGLTLMWN 148
Query: 2193 GDSFVRLRVPAAYAASLCGLCGNYNQ-DPADDLKAVGGKPAGWQVGGAQG-------CGE 2244
+ + L + + CGLCG+YN + + G + + G Q C +
Sbjct: 149 REDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLEFGNMQKINQPDVVCED 208
Query: 2245 CVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGH 2304
+ P+ C+ + E C + + A C LVP Y + C D C+ G
Sbjct: 209 PEEEVAPASCSEHRAE-------CERLLTAEA-FADCQDLVPLEPYLRACQQDRCRCPGG 260
Query: 2305 PGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEG 2364
+C VA + C AG + G WR CP CP + Y G C +C L
Sbjct: 261 DTCVCSTVAEFSRQCSHAGGRPGNWRTATLCPKTCPGNLVYLESGSPCMDTCSHLEVSSL 320
Query: 2365 CESACREGCVCDAGFVLS--GDT-CVPVGQCGC-LHDGRYYPLGEVFYPGPECERRCECG 2420
CE +GC C G V GD+ CVPV QC C LH G ++ PG E C
Sbjct: 321 CEEHRMDGCFCPEGTVYDDIGDSGCVPVSQCHCRLH-------GHLYTPGQEITNDC--- 370
Query: 2421 PGGHVTCQEGAACGPHEECRLEDGVQACHATGC-GRCLANGGIHYITLDGRVYDLHGSCS 2479
E+C G C C G C GG H T DG+ Y HG C
Sbjct: 371 ----------------EQCVCNAGRWVCKDLPCPGTCALEGGSHITTFDGKTYTFHGDCY 414
Query: 2480 YVLAQVCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVSLAQGQQVTV----DGEAVA 2535
YVLA+ H ++ ++++ E G + T VV LA ++ V DG +
Sbjct: 415 YVLAKGDH----NDSYALLGELAPCGSTDK--QTCLKTVVLLADKKKNVVVFKSDGSVLL 468
Query: 2536 LPVAVGRVRVTA-------EGRNMVLQTTKGLRLLFD--GDAHLLMSIPSPFRGRLCGLC 2586
+ V VTA ++++ G+RL L +++ +G++ GLC
Sbjct: 469 NELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGLC 528
Query: 2587 GNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYES 2646
GNFNG DDF +G ++ F W+A S C + P L E+A Y +
Sbjct: 529 GNFNGLEGDDFKTASGLVEATGAGFANTWKAQSS---CHDKLDWLDDPCSLNIESANY-A 584
Query: 2647 NEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGV 2706
C L+ + PF C + + P+EY+++C YD C + ++ LC +L++Y AC A GV
Sbjct: 585 EHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGV 644
Query: 2707 AVKPWRTDSFCPL---HCPAHSHYSICTRTCQGSCAALSGLTGCTTRCF---EGCECDDR 2760
+ WR + C CP + TCQ +C +LS F +GC C D
Sbjct: 645 MLWGWR-EHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGCPDH 703
Query: 2761 -FLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSC------------------- 2800
FL +G C+P+ C C H G YL ++ + ERC C
Sbjct: 704 TFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQE--ERCVCRDGRLHCRQIRLIGQSCTA 761
Query: 2801 ---------------SSSSGLTCQ--AAG-----CPPGRVC------------------- 2819
S L+CQ AAG C G VC
Sbjct: 762 PKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDGLMDDGRGGCVVEKECP 821
Query: 2820 ------------EVKAEARNCWATRG--LCVLSVGANLTTFDGARGATTSPG-VYELSSR 2864
++K + C RG +C +V + G+ T G Y+
Sbjct: 822 CVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDFDGH 881
Query: 2865 CPGLQNTIPWYRVVAEVQICHGKTEAVGQVHIFFQD---GMVTLTPNKGVWVNGLRVDLP 2921
C VA C G+ ++G I ++ G +T +K + + R +L
Sbjct: 882 C----------SYVAVQDYC-GQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELK 930
Query: 2922 AEKLASVSVSRTPDGS-----------LLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCG 2970
E V + R L+V G+ V V + ++ + G +CG
Sbjct: 931 LEDKHRVVIQRDEGHHVAYTTREVGQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCG 990
Query: 2971 ACGNFDGDQTNDW 2983
CGNFD ND+
Sbjct: 991 LCGNFDHRSNNDF 1003
Score = 246 bits (627), Expect = 3e-64
Identities = 219/803 (27%), Positives = 314/803 (39%), Gaps = 92/803 (11%)
Query: 444 CEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCS 503
C + A G Q G VC G+ HY TFDG + G C Y C
Sbjct: 12 CLALSLAGGSELQTEGRTRN---HGHNVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCR 68
Query: 504 EDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEV----GFVLVDNQRSRL 559
+ F+V K + + V + + ++ LTR V + L
Sbjct: 69 --GSYKEFAVHLKRGPGQAEAPAGVESILLTIKDDTIYLTRHLAVLNGAVVSTPHYSPGL 126
Query: 560 PVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPA 619
+ S+ +VY GL + ++ + L L L +F++ CGLCG+YNG +
Sbjct: 127 LIEKSDAYTKVYSRA---------GLTLMWNREDALMLELDTKFRNHTCGLCGDYNGLQS 177
Query: 620 DDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPA-CTPGQAQHYEGDRLCGMLT 678
DG L +EF + K++ D +CED + PA C+ +A+ C L
Sbjct: 178 YSEFLSDGVLF-SPLEFGNMQKINQPDVVCEDPEEEVAPASCSEHRAE-------CERLL 229
Query: 679 KLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSP 738
+ FA C D + P+L C D C G +C ++ +++ C G G+WR+
Sbjct: 230 TAEA-FADCQDLVPLEPYLRACQQDRCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTA 288
Query: 739 ANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFV---ASGGACVP 795
CP +CP N Y G C +C+ S C ++GC C G V CVP
Sbjct: 289 TLCPKTCPGNLVYLESGSPCMDTCSHLEVSSLCEEHR-MDGCFCPEGTVYDDIGDSGCVP 347
Query: 796 ASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLG 855
S C C G PGQE+ D C+ +C CN + C+D CP
Sbjct: 348 VSQCHCRLHGHLYTPGQEITND--CE-QCVCNAG--RWVCKD-LPCP------------- 388
Query: 856 CYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQ 915
GTC G H +FDG+ + F G C Y+L N + L Q
Sbjct: 389 ------GTCALEGGSHITTFDGKTYTFHGDCYYVLAKG-DHNDSYALLGELAPCGSTDKQ 441
Query: 916 TVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFR-QGRDAVVRTD 974
T T + + + V + + G VL++++ LP A VFR +V
Sbjct: 442 TCLKTVVLLADKKKNVVVFKSD--GSVLLNELQVNLPHVTA--SFSVFRPSSYHIMVSMA 497
Query: 975 FGLTVTYDWNARVTAKVPSSYAE--ALCGLCGNFNGDPADDLALRGGGQAANALAFGNSW 1032
G+ + + V A + GLCGNFNG DD G A F N+W
Sbjct: 498 IGVRLQVQLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTW 557
Query: 1033 QEETRPGCGATEPGDCPKLDSLVAQQLQSKNE----CGILADPKGPFRECHSKLDPQGAV 1088
+ ++ C LD + ++S N C +L + PF CHS +DP
Sbjct: 558 KAQS--SC----HDKLDWLDDPCSLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYY 611
Query: 1089 RDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPL---SCPPHSHYEAC 1145
+ C YD C LC AL++YA AC A G + WR E +C SCP +
Sbjct: 612 KRCKYDTCNCQNNEDCLCAALSSYARACTAKGVMLWGWR-EHVCNKDVGSCPNSQVFLYN 670
Query: 1146 SYGCPLSCGDLPVPGGCGSECHE------GCVC-DEGFALSGESCLPLASCGCVHQGTYH 1198
C +C L S C E GC C D F C+PLA C C H+G Y
Sbjct: 671 LTTCQQTCRSL---SEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYL 727
Query: 1199 PPGQTFYPGPGCDSLCHCQEGGL 1221
G + C C++G L
Sbjct: 728 EAGDVVVRQ---EERCVCRDGRL 747
Score = 219 bits (557), Expect = 4e-56
Identities = 241/892 (27%), Positives = 339/892 (38%), Gaps = 137/892 (15%)
Query: 1248 GSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSV 1307
G + C G+ HY TFDG F F G C Y A C R FAV ++ G G+
Sbjct: 33 GHNVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDC--RGSYKEFAV---HLKRGPGQAEA 87
Query: 1308 ---TRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGL 1364
I + + + T+ L + +NG + P I S + V GL
Sbjct: 88 PAGVESILLTIKDDTIYLTRHL--AVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRA--GL 143
Query: 1365 RVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVP 1424
+ ++ + + + + CGLCG+YNG +G EFGN + P
Sbjct: 144 TLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPL-EFGNMQKINQP 202
Query: 1425 DSPCLPPTPCPPGSEDCIPS----HKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDP 1480
D C P E+ P+ H+ E E+ E F + C LV
Sbjct: 203 DVVCEDP------EEEVAPASCSEHRA--ECERLLTAEAF-----------ADCQDLVPL 243
Query: 1481 QGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYEL 1540
+ L+ C D C G + +CS + + C AGG WRT T CP CP N Y
Sbjct: 244 EPYLRACQQDRCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATLCPKTCPGNLVYLE 303
Query: 1541 CADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYN---GQACVPIQQCGCYHNGVYYEPE 1597
C CS L C++ +GC C G +Y+ CVP+ QC C +G Y P
Sbjct: 304 SGSPCMDTCSHLEVSSLCEEHRMDGCFCPEGTVYDDIGDSGCVPVSQCHCRLHGHLYTPG 363
Query: 1598 QTVLIDNCRQQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCK 1657
Q I N +QC C+AG+ VC++ C PG
Sbjct: 364 QE--ITNDCEQCVCNAGR-WVCKDLPC-PG------------------------------ 389
Query: 1658 EQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLAT-TGCPGVSTQG-LTPF 1715
TC L G H +FDG+ + F G C YVLA + G L P
Sbjct: 390 --------------TCALEGGSHITTFDGKTYTFHGDCYYVLAKGDHNDSYALLGELAPC 435
Query: 1716 TVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRIS 1775
T K VV +A N+ + K + V +N + LP A S
Sbjct: 436 GSTDKQ-------TCLKTVVLLADKKKNVVVFKSD---GSVLLNELQVNLPHVTAS--FS 483
Query: 1776 VAQGASKALLVA---DFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPN 1832
V + +S ++V+ LQV ++ VTL + G V GLCGN + +D +
Sbjct: 484 VFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTAS 543
Query: 1833 GTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLASGTGGPFT 1892
G + + + +W+A C D+ C + +C L T PF
Sbjct: 544 GLVEATGAGFANTWKA---QSSCHDKLDWLDDPCSLNIESANYAEHWCS-LLKKTETPFG 599
Query: 1893 TCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEI-- 1950
CH+ V P ++K C D C + D LC AL+SY AC A GV++ WR V C
Sbjct: 600 RCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGVMLWGWREHV-CNKDV 658
Query: 1951 -TCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQC-DAGFVLSADRCVPLNNG 2008
+CP + + C +C S + + + V+GC C D F+ RCVPL
Sbjct: 659 GSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAK- 717
Query: 2009 CGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQP 2068
C C+ G Y EAG D Q RC G L C +G+ C P C
Sbjct: 718 CSCYHRGLYLEAG-----DVVVRQEERCVCRDGRLHCRQIRL-IGQSC-TAPKIHMDCSN 770
Query: 2069 VS--------TAECQAWGDPHY--------VTLDGHRFDFQGTCEYLLSAPC 2104
++ CQ +Y V DG D +G C PC
Sbjct: 771 LTALATSKPRALSCQTLAAGYYHTECVSGCVCPDGLMDDGRGGCVVEKECPC 822
Score = 180 bits (456), Expect = 2e-44
Identities = 137/466 (29%), Positives = 206/466 (44%), Gaps = 57/466 (12%)
Query: 776 CVEGCVCLPGFVASG-GACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVT 834
CV GCVC G + G G CV C C + G ++ D CN T
Sbjct: 796 CVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVD--------CN------T 841
Query: 835 CRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGS- 893
C +C G Q C+ GTC G HY++FDG+ +DF G C+Y+ V
Sbjct: 842 C----TCKRGRWVCTQ---AVCH----GTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDY 890
Query: 894 CGQNAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPF 953
CGQN++L +F ++ EN G+ V+ ++A+++ ++ + ++ V+ D ++ +
Sbjct: 891 CGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHR-VVIQRDEGHHVAY 949
Query: 954 QAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADD 1013
+ G+ VV + G+ V +D V K+ SY +CGLCGNF+ +D
Sbjct: 950 TTRE-------VGQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNND 1002
Query: 1014 LALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKG 1073
R ++ L FGNSW+E +T P C ++ ++ +C IL
Sbjct: 1003 FTTRDHMVVSSELDFGNSWKEAPTCPDVSTNPEPCSLNPH---RRSWAEKQCSIL--KSS 1057
Query: 1074 PFRECHSKLDPQGAVRDCVYDRCLLP--GQSGPLCDALATYAAACQAAGATVHPWRSEEL 1131
F CHSK+DP+ CV+D C G C A+A+YA C GA V WR+ +L
Sbjct: 1058 VFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACVF-WRTPDL 1116
Query: 1132 CPLSC----PPHS---HYEACSYGCPLSCGDL-PVPGGCGSECHEGCV--CDEGFALSGE 1181
CP+ C PPH HYE C +C + + EGC C + + E
Sbjct: 1117 CPIFCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEE 1176
Query: 1182 ---SCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSC 1224
C+ CGC + T++PPG + C S C C V C
Sbjct: 1177 DLKKCVTADKCGCYVEDTHYPPGASVPTEETCKS-CVCTNSSQVVC 1221
Score = 176 bits (447), Expect = 2e-43
Identities = 173/675 (25%), Positives = 248/675 (36%), Gaps = 105/675 (15%)
Query: 1079 HSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCP- 1137
H+ LD +G C G D + C +H R L SC
Sbjct: 703 HTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEERCVCRDGRLH-CRQIRLIGQSCTA 761
Query: 1138 PHSHYE-------ACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGES-CLPLASC 1189
P H + A S LSC L G +EC GCVC +G G C+ C
Sbjct: 762 PKIHMDCSNLTALATSKPRALSCQTLAA-GYYHTECVSGCVCPDGLMDDGRGGCVVEKEC 820
Query: 1190 GCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGS 1249
CVH + G C++ C C+ G V + AV
Sbjct: 821 PCVHNNDLYSSGAKIKVD--CNT-CTCKRGRWVCTQ--------------------AVCH 857
Query: 1250 STCQASGDPHYTTFDGRRFDFMGTCVYVLAQT-CGTRPGLHRFAVLQENVAWGNGRVSVT 1308
TC G HY TFDG+ +DF G C YV Q CG L F+++ ENV G V+ +
Sbjct: 858 GTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVTCS 917
Query: 1309 RVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAY 1368
+ I + + L+LE + V D V ++ G +V+E+ G+ V +
Sbjct: 918 KAIKIFMGRTELKLEDKHRVVIQR--DEGHHVAYTTREV-----GQYLVVESSTGIIVIW 970
Query: 1369 DLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPC 1428
D V + + +Y +CGLCGN++ +DF + + +FGNSW+E P P
Sbjct: 971 DKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKE-APTCPD 1029
Query: 1429 LPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCI 1488
+ P P C ++ E+ C +L S S CH VDP+ + C+
Sbjct: 1030 VSTNPEP-----------CSLNPHRRSWAEKQCSILKSSV--FSICHSKVDPKPFYEACV 1076
Query: 1489 FDLCL--GGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMEC----PPNS---HYE 1539
D C GG+ CS + +Y C G V WRT CP+ C PP+ HYE
Sbjct: 1077 HDSCSCDTGGDCECFCSAVASYAQECTKEGACVF-WRTPDLCPIFCDYYNPPHECEWHYE 1135
Query: 1540 LCADTCSLGCSALSA-----PPQCQDGCAEGCQCDSGFLYNG-QACVPIQQCGCYHNGVY 1593
C + C ++ +GC C D + CV +CGCY +
Sbjct: 1136 PCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTH 1195
Query: 1594 YEPEQTVLIDNCRQQCTCHAGKGMVCQEHSCK-----------PGQVCQPSGGI-----L 1637
Y P +V + + C C +VC+ K ++C P+G + +
Sbjct: 1196 YPPGASVPTEETCKSCVCTNSSQVVCRPEEGKILNQTQDGAFCYWEICGPNGTVEKHFNI 1255
Query: 1638 SCVTKDPCHGVTCR-----------PQETCKEQGGQGVCLPNYEATCWLWGD------PH 1680
+T P T T L C LW D P
Sbjct: 1256 CSITTRPSTLTTFTTITLPTTPTTFTTTTTTTTPTSSTVLSTTPKLCCLWSDWINEDHPS 1315
Query: 1681 YHSFDGRKFDFQGTC 1695
S DG + F G C
Sbjct: 1316 SGSDDGDRETFDGVC 1330
Score = 160 bits (404), Expect = 2e-38
Identities = 118/404 (29%), Positives = 178/404 (44%), Gaps = 39/404 (9%)
Query: 455 CQVVGGKAGCV-AESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVE-LCSEDDTLPAFS 512
C G+ C A C G HY TFDG+ YD G CSY V+ C ++ +L +FS
Sbjct: 842 CTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFS 901
Query: 513 VEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQ 572
+ +N G+ V+ S ++ + G L D + R+ + EG Y
Sbjct: 902 IITENVPCGTTGVTC---------SKAIKIFMGRTELKLED--KHRVVIQRDEGHHVAYT 950
Query: 573 S---GPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGAL 629
+ G VVE G++V +D + + L ++ VCGLCGN++ +DF T D +
Sbjct: 951 TREVGQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMV 1010
Query: 630 APDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHD 689
++F +SWK C D N P C+ + ++ C +L F++CH
Sbjct: 1011 VSSELDFGNSWKEAP---TCPDVSTNPEP-CSLNPHRRSWAEKQCSILK--SSVFSICHS 1064
Query: 690 TLDPRPFLEQCVYDLCV--VGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSC-- 745
+DP+PF E CV+D C GG+ C +++YAQ C + G V WR+P CP+ C
Sbjct: 1065 KVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACV-FWRTPDLCPIFCDY 1123
Query: 746 -----PANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCV--C---LPGFVASGGACVP 795
YE CG +C + +EGC C P + CV
Sbjct: 1124 YNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVT 1183
Query: 796 ASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQ 839
A CGC + PG V +E C + C C ++ QV CR ++
Sbjct: 1184 ADKCGCYVEDTHYPPGASVPTEETC-KSCVCTNSS-QVVCRPEE 1225
Score = 141 bits (356), Expect = 8e-33
Identities = 122/393 (31%), Positives = 177/393 (45%), Gaps = 43/393 (10%)
Query: 472 CRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRGS--RRVSYVG 529
C +G H TTFDG+ Y G C Y + ++ D ++++ + GS ++
Sbjct: 391 CALEGGSHITTFDGKTYTFHGDCYYVL----AKGDHNDSYALLGELAPCGSTDKQTCLKT 446
Query: 530 LVTVRAYSHSVSLTRGEVGFVLVDNQRSRLP-VSLSEGRLRVYQSGPRAVVELVFG--LV 586
+V + +V + + + G VL++ + LP V+ S R S +V + G L
Sbjct: 447 VVLLADKKKNVVVFKSD-GSVLLNELQVNLPHVTASFSVFR--PSSYHIMVSMAIGVRLQ 503
Query: 587 VTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKL---- 642
V QL ++L Q QV GLCGN+NG DDF T G + FA++WK
Sbjct: 504 VQLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSC 563
Query: 643 -DDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCV 701
D D+L +D C N + A+H+ C +L K + PF CH +DP + ++C
Sbjct: 564 HDKLDWL-DDPCSLNIESAN--YAEHW-----CSLLKKTETPFGRCHSAVDPAEYYKRCK 615
Query: 702 YDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPL---SCPANSRYELCGPAC 758
YD C LC LS+YA+AC G+ + WR C SCP + + C
Sbjct: 616 YDTCNCQNNEDCLCAALSSYARACTAKGVMLWGWREHV-CNKDVGSCPNSQVFLYNLTTC 674
Query: 759 PTSCNG-AAAPSNC-SGRPCVEGCVCLP-GFVASGGACVPASSCGCTFQGLQLAPGQEVW 815
+C + A S+C G V+GC C F+ G CVP + C C +GL L G V
Sbjct: 675 QQTCRSLSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVV 734
Query: 816 ADELCQRRCTC-NGATHQVTCRD----KQSCPA 843
E RC C +G H CR QSC A
Sbjct: 735 RQE---ERCVCRDGRLH---CRQIRLIGQSCTA 761
Score = 139 bits (350), Expect = 4e-32
Identities = 121/484 (25%), Positives = 191/484 (39%), Gaps = 76/484 (15%)
Query: 1985 CVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLV 2044
CV GC C G + + C C N + +G++ D C+ C C G V
Sbjct: 796 CVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVD--CNT-CTCKRG--RWV 850
Query: 2045 CTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPC 2104
CT A C HG C +G HY+T DG +DF G C Y+
Sbjct: 851 CTQAVC-------------HGT-------CSIYGSGHYITFDGKYYDFDGHCSYVAVQDY 890
Query: 2105 HGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD-GVFVALP 2163
G +F++ N G+ V+ ++++ + + L L + +Q D G VA
Sbjct: 891 CGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYT 950
Query: 2164 FQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADD 2223
G +VV +++G+ + +D + V +++ +Y ++CGLCGN++ +D
Sbjct: 951 --------TREVGQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNND 1002
Query: 2224 LKAVGGKPAGWQVGGAQGCGECVSKP----CPSPCTPEQQESFGGPDACGVISATDGPLA 2279
++ E + P P PC+ C ++ ++ +
Sbjct: 1003 FTTRDHMVVSSELDFGNSWKEAPTCPDVSTNPEPCSLNPHRRSWAEKQCSILKSS--VFS 1060
Query: 2280 PCHGLVPPAQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPL 2337
CH V P +++ C+ D+C G C AVA+Y C GA + WR PD CP+
Sbjct: 1061 ICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACV-FWRTPDLCPI 1119
Query: 2338 QC----PAHS---HYELCGDSCPVSCP---------SLSAPEGCESAC-REGCVCDAGFV 2380
C P H HYE CG+ +C S+S EGC C ++ + +
Sbjct: 1120 FCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDL- 1178
Query: 2381 LSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTC-----------QE 2429
CV +CGC + +YP G P E + C C V C Q+
Sbjct: 1179 ---KKCVTADKCGCYVEDTHYPPG-ASVPTEETCKSCVCTNSSQVVCRPEEGKILNQTQD 1234
Query: 2430 GAAC 2433
GA C
Sbjct: 1235 GAFC 1238
Score = 138 bits (348), Expect = 7e-32
Identities = 126/429 (29%), Positives = 188/429 (43%), Gaps = 37/429 (8%)
Query: 449 CAAGQRCQVVGGKAGCVA--ESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDD 506
C+ G + V GC E C GDPHY TFDG Y G C+Y +VE S
Sbjct: 4456 CSNGLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEIS--P 4513
Query: 507 TLPAFSVEAKNEH-RGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSE 565
++ F V N H + +VS + VR + V + + + V Q +R V+L
Sbjct: 4514 SVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPY 4573
Query: 566 GR--LRVYQSGPRAVVEL-VFGLVVTYDWDCQLALSLP-ARFQDQVCGLCGNYNGDPADD 621
+ L VYQSG VV++ G++V+Y+ ++ LP RF + G CG +DD
Sbjct: 4574 KKYGLEVYQSGINYVVDIPELGVLVSYN-GLSFSVRLPYHRFGNNTKGQCGTCTNTTSDD 4632
Query: 622 FLTPDGALAPDAVEFASSWKLDDGD--YLCEDGCQNNCPACT-PGQAQ---HYE--GDRL 673
+ P G + + A W ++D + PA T PG + H + L
Sbjct: 4633 CILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPL 4692
Query: 674 CGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVG 733
C ++ D FA CH + P+ + + CV+D C + G L C L AYA C + I +
Sbjct: 4693 CQLIK--DSLFAQCHALVPPQHYYDACVFDSCFMPGSSLE-CASLQAYAALCAQQNICL- 4748
Query: 734 DWRSPAN--CPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFV-ASG 790
DWR+ + C + CP++ Y+ CGPA +C +++ N VEGC C G + +
Sbjct: 4749 DWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQN--NTVLVEGCFCPEGTMNYAP 4806
Query: 791 GACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQ 850
G V +CGC G P + E + C C + C+ K RCS Q
Sbjct: 4807 GFDVCVKTCGCV--GPDNVPREFGEHFEFDCKNCVCLEGGSGIICQPK-------RCS-Q 4856
Query: 851 NGLLGCYPD 859
+ C D
Sbjct: 4857 KPVTHCVED 4865
Score = 129 bits (323), Expect = 6e-29
Identities = 124/453 (27%), Positives = 171/453 (37%), Gaps = 58/453 (12%)
Query: 1652 PQETCKEQGGQGVCLPNYEATCWLW---------GDPHYHSFDGRKFDFQGTCNYVLATT 1702
P TC G Q V + + + CW W GDPHY +FDG + +QG C YVL
Sbjct: 4452 PMPTCSN-GLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEE 4510
Query: 1703 GCPGVSTQGLTPFTV-TTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGV 1761
P V G+ N P VR T L + + + V+V VN
Sbjct: 4511 ISPSVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQ---VQVQVNRQ 4567
Query: 1762 LTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYH---GAVCGLCG 1818
ALP G G + + + + G+ VSY+ V LP YH G CG
Sbjct: 4568 AVALPYK-KYGLEVYQSGINYVVDIPELGVLVSYN-GLSFSVRLP--YHRFGNNTKGQCG 4623
Query: 1819 NMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCP---TCPEDRLEQYE 1875
++D + P+G + + W L D + CP + +
Sbjct: 4624 TCTNTTSDDCILPSGEIVSNCEAAADQW-------LVNDPSKPHCPHSSSTTKRPAVTVP 4676
Query: 1876 GPGFCGPLASGTGGP---------FTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALA 1926
G G P T P F CHA VPP+ ++ CV D C G + C +L
Sbjct: 4677 GGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSCFMPGS-SLECASLQ 4735
Query: 1927 SYVAACQAAGVVIEDWRAQV--GCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGP 1984
+Y A C + + DWR C + CP + Y+ CGP +C S + V
Sbjct: 4736 AYAALCAQQNICL-DWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQNNTV---- 4790
Query: 1985 CVEGCQCDAG---FVLSADRCVPLNNGCGC-WANGTYHEAGSEFWADGTCSQWCRCGPGG 2040
VEGC C G + D CV CGC + E G F D C C C GG
Sbjct: 4791 LVEGCFCPEGTMNYAPGFDVCV---KTCGCVGPDNVPREFGEHFEFD--CKN-CVCLEGG 4844
Query: 2041 GSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAE 2073
++C P C V + G + V+ A+
Sbjct: 4845 SGIICQPKRCSQKPVTHCVEDGTYLATEVNPAD 4877
Score = 128 bits (322), Expect = 7e-29
Identities = 127/447 (28%), Positives = 178/447 (39%), Gaps = 51/447 (11%)
Query: 1252 CQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWG-NGRVSVTRV 1310
C GDPHY TFDG + + G C YVL + P + F V +N N +VS R
Sbjct: 4481 CTGWGDPHYVTFDGLYYSYQGNCTYVLVEEIS--PSVDNFGVYIDNYHCDPNDKVSCPRT 4538
Query: 1311 I-----TVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIE-TDFGL 1364
+ T +V T+ + Q +V VN + LP + Q G + V++ + G+
Sbjct: 4539 LIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALP--YKKYGLEVYQSGINYVVDIPELGV 4596
Query: 1365 RVAYD-LVYYVRVTVP--GNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEE 1421
V+Y+ L + VR+ GN + CG C N DD P+G N + W
Sbjct: 4597 LVSYNGLSFSVRLPYHRFGNNTKGQCGTCTN---TTSDDCILPSGEIVSNCEAAADQWLV 4653
Query: 1422 VVPDSPCLP--------PTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSS 1473
P P P P PG P C P C L+ +
Sbjct: 4654 NDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTP--------SPLCQLIKDSL--FAQ 4703
Query: 1474 CHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETF--CPME 1531
CH LV PQ C+FD C G+ S+ C+++ AY + C A WR T C +E
Sbjct: 4704 CHALVPPQHYYDACVFDSCFMPGS-SLECASLQAYAALC-AQQNICLDWRNHTHGACLVE 4761
Query: 1532 CPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFL-YNGQACVPIQQCGCY-H 1589
CP + Y+ C C + S+ Q EGC C G + Y V ++ CGC
Sbjct: 4762 CPSHREYQACGPAEEPTCKS-SSSQQNNTVLVEGCFCPEGTMNYAPGFDVCVKTCGCVGP 4820
Query: 1590 NGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEHSC--KPGQVCQPSGGILSCVTK--DPC 1645
+ V E + D C+ G G++CQ C KP C G L+ D C
Sbjct: 4821 DNVPREFGEHFEFD-CKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTC 4879
Query: 1646 HGVTCRPQET--CKEQGGQGVCLPNYE 1670
+T T CKE+ VC +E
Sbjct: 4880 CNITVCKCNTSLCKEK--PSVCPLGFE 4904
Score = 125 bits (314), Expect = 6e-28
Identities = 113/425 (26%), Positives = 166/425 (39%), Gaps = 42/425 (9%)
Query: 2416 RCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCG-RCLANGGIHYITLDGRVYDL 2474
+ EC P TC G + R+ED C C C G HY+T DG Y
Sbjct: 4445 KVECEPPPMPTCSNGL-----QPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSY 4499
Query: 2475 HGSCSYVLAQVCHPKPGDEDFSIVLEK-----NAAGDLQRLLV-------TVAGQVVSLA 2522
G+C+YVL + P ++F + ++ N R L+ + V +
Sbjct: 4500 QGNCTYVLVE--EISPSVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMP 4557
Query: 2523 QGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTK-GLRLLFDGDAHLLMSIPSP---F 2578
QV V+ +AVALP + V G N V+ + G+ + ++G L S+ P F
Sbjct: 4558 MQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVLVSYNG---LSFSVRLPYHRF 4614
Query: 2579 RGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSK-GCGEGCGPQGCPVCL 2637
G CG SDD +LP+G S+ E W SK C P
Sbjct: 4615 GNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVT 4674
Query: 2638 AE---ETAPYES---NEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLC 2691
+T P++ + C +++ FA C A++ P Y+ CV+D C G + C
Sbjct: 4675 VPGGGKTTPHKDCTPSPLCQLIKD--SLFAQCHALVPPQHYYDACVFDSCFMPG-SSLEC 4731
Query: 2692 RSLAAYTAACQAAGVAVKPWR--TDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTT 2749
SL AY A C + + WR T C + CP+H Y C + +C + S T
Sbjct: 4732 ASLQAYAALCAQQNICL-DWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQN-NT 4789
Query: 2750 RCFEGCECDDRFL-LSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTC 2808
EGC C + + + G + V+ CGC DC SG+ C
Sbjct: 4790 VLVEGCFCPEGTMNYAPGFDVCVKTCGCVGPDNVPREFGEHFEFDCKNCVCLEGGSGIIC 4849
Query: 2809 QAAGC 2813
Q C
Sbjct: 4850 QPKRC 4854
Score = 119 bits (297), Expect = 6e-26
Identities = 121/456 (26%), Positives = 178/456 (39%), Gaps = 59/456 (12%)
Query: 825 TCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMG 884
TC+ V D C C CY C G GDPHYV+FDG + + G
Sbjct: 4455 TCSNGLQPVRVEDPDGCCWHWECD-------CY------CTGWGDPHYVTFDGLYYSYQG 4501
Query: 885 TCTYLLVGSCGQNAALPAFRVLVENEH---RGSQTVSYTRAVRVEARGVKVAVRREYPGQ 941
CTY+LV + ++ F V ++N H + T VR E + V + P Q
Sbjct: 4502 NCTYVLVEEI--SPSVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQ 4559
Query: 942 VLVDDVLQYLPFQAADGQVQVFRQGRDAVVR-TDFGLTVTYDWNARVTAKVP-SSYAEAL 999
V V Q + ++V++ G + VV + G+ V+Y+ + ++P +
Sbjct: 4560 VQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVLVSYN-GLSFSVRLPYHRFGNNT 4618
Query: 1000 CGLCGNFNGDPADDLALRGGGQAANALAFGNSW--QEETRPGC----------GATEPG- 1046
G CG +DD L G +N A + W + ++P C T PG
Sbjct: 4619 KGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGG 4678
Query: 1047 --DCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGP 1104
P D + C ++ D F +CH+ + PQ CV+D C +PG S
Sbjct: 4679 GKTTPHKDCTPSPL------CQLIKD--SLFAQCHALVPPQHYYDACVFDSCFMPGSSLE 4730
Query: 1105 LCDALATYAAACQAAGATVHPWRSEE--LCPLSCPPHSHYEACSYGCPLSCGDLPVPGGC 1162
C +L YAA C + WR+ C + CP H Y+AC +C
Sbjct: 4731 -CASLQAYAALCAQQNICL-DWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQN- 4787
Query: 1163 GSECHEGCVCDEG---FALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEG 1219
+ EGC C EG +A + C + +CGCV G + P + C C EG
Sbjct: 4788 NTVLVEGCFCPEGTMNYAPGFDVC--VKTCGCV--GPDNVPREFGEHFEFDCKNCVCLEG 4843
Query: 1220 GL-VSCESSSCG--PHEACQPSGGSLGCVAVGSSTC 1252
G + C+ C P C G L + TC
Sbjct: 4844 GSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTC 4879
Score = 117 bits (294), Expect = 1e-25
Identities = 119/428 (27%), Positives = 183/428 (42%), Gaps = 56/428 (13%)
Query: 2059 LPSGQHGCQPVSTAE-------------CQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCH 2105
+P+ +G QPV + C WGDPHYVT DG + +QG C Y+L
Sbjct: 4453 MPTCSNGLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEIS 4512
Query: 2106 GPPLGAENFTVTVANEH-RGSQAVSYTRSVTLQIYNHSLTLSA----RWPRKLQVDGVFV 2160
+NF V + N H + VS R++ ++ + + ++QV+ V
Sbjct: 4513 P---SVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAV 4569
Query: 2161 ALPFQLDSLLHAHLSGADVVVTTTS-GLSLAFDGDSFVRLRVP-AAYAASLCGLCGNYNQ 2218
ALP++ L + SG + VV G+ ++++G SF +R+P + + G CG
Sbjct: 4570 ALPYKKYG-LEVYQSGINYVVDIPELGVLVSYNGLSF-SVRLPYHRFGNNTKGQCGTCTN 4627
Query: 2219 DPADDLKAVGGK-PAGWQVGGAQGCGECVSKP-CPSPCTPEQQESF---GGPDACGVISA 2273
+DD G+ + + Q SKP CP + ++ + GG
Sbjct: 4628 TTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDC 4687
Query: 2274 TDGPL---------APCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGA 2324
T PL A CH LVPP Y+ C+ D+C + G C ++ Y A C
Sbjct: 4688 TPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSCFMPG-SSLECASLQAYAALCAQQNI 4746
Query: 2325 QLGEWRRPDF--CPLQCPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAG---F 2379
L +WR C ++CP+H Y+ CG + +C S S+ + + EGC C G +
Sbjct: 4747 CL-DWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQN-NTVLVEGCFCPEGTMNY 4804
Query: 2380 VLSGDTCVPVGQCGCL-HDGRYYPLGEVFYPGPECERRCECGPGGH-VTCQ-EGAACGPH 2436
D CV CGC+ D GE F +C + C C GG + CQ + + P
Sbjct: 4805 APGFDVCVKT--CGCVGPDNVPREFGEHF--EFDC-KNCVCLEGGSGIICQPKRCSQKPV 4859
Query: 2437 EECRLEDG 2444
C +EDG
Sbjct: 4860 THC-VEDG 4866
>gi|239755901 PREDICTED: chromosome 12 open reading frame 64 [Homo
sapiens]
Length = 2250
Score = 319 bits (818), Expect = 2e-86
Identities = 290/1160 (25%), Positives = 472/1160 (40%), Gaps = 170/1160 (14%)
Query: 450 AAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLP 509
A G RCQ++ +C+ G H+ TFDG Y G CSY + C D P
Sbjct: 45 ALGTRCQIIPNMGN---GRDGICKTWGQYHFETFDGIYYYFPGNCSYIFAKDCG--DLEP 99
Query: 510 AFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSL---TRGEVGFVLVDNQRSRLPVSLSE- 565
++V N + L +V + S+SL + E+ + +++ + ++L +
Sbjct: 100 RYTVWVHNSPKC--------LGSVYSCYRSISLFFSNQEEIRIYGHEIKKNGISLTLPQT 151
Query: 566 -GRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLT 624
G++ + + +V+ FG + +D + L L + + CGLCGNYN +DDF+
Sbjct: 152 IGQIFIEKLADYILVKTTFGFSLAWDGISGIYLKLSEDHKGKSCGLCGNYNDIQSDDFII 211
Query: 625 PDGALAPDAVEFASSWKLDDGD----YLCEDGCQNNCPACTPG-QAQHYEGDRLCGMLTK 679
D FA+SW + D L N C + P +A ++ C +L
Sbjct: 212 LQEDYTEDIAMFANSWSVQTPDDTKCVLTPSDFPNPCSSGMPAFEAIFFK----CQIL-- 265
Query: 680 LDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRS-- 737
L PF CH+ +DP ++ CV DLC + + CR + YA+AC G + DWR
Sbjct: 266 LQFPFLSCHEYIDPYLYIASCVNDLCKTDDDE-TYCRAATEYARACSHAGYPIQDWRDDF 324
Query: 738 PANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGR--PCVEGCVCLPGFVASGGACVP 795
PA C C + + C CP +C C G C++GC C G V G C+
Sbjct: 325 PA-CTDKCDDSFVHRDCISCCPPTC---TFEKQCLGSNLHCLDGCYCPDGLVMDNGTCIS 380
Query: 796 ASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLG 855
+C C F GL + G ++ ++ C C C G T +Q CP +CSV
Sbjct: 381 LENCPCGFHGLAYSVGSKI--EQEC-TECVCVGGVWNCT---EQDCPV--QCSV------ 426
Query: 856 CYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQ 915
GD H+ +FDGR + F+G C Y+LV G++ + ++ G
Sbjct: 427 -----------VGDSHFTTFDGRHYSFIGMCQYILVKGTGKDKFTITLQKAPCEQNLGLV 475
Query: 916 TVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQA--ADGQVQV-FRQGRDAVVR 972
+ + + +V + R GQ+L P Q +G V++ +++
Sbjct: 476 CLQSITLILEDDFNKQVTLGR--GGQILTS------PNQGFNLNGIVEIQTLSSLFILLK 527
Query: 973 TDFGLTVTYDWNA-RVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNS 1031
T FGL + + + R+ ++ S++ GLCG FNG+ DD G N+
Sbjct: 528 TTFGLKILFAIDGERIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEGTPQLHANA 587
Query: 1032 WQEETRPGCGATEPGDCPKLD--SLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVR 1089
W+ + C A P P +D ++ Q + C ++ F CH + P +
Sbjct: 588 WRVSST--CFA--PVHVPVVDPCNINQQNIGYAAHCDVIHQEL--FAPCHIYISPGLYYQ 641
Query: 1090 DCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGC 1149
C +D C S LC+ALA YA C G + C + C Y CS C
Sbjct: 642 LCRHDACKC--GSSCLCNALAHYAYLCGQHGVPIDFRTQISFCAVVCQKGMLYHHCSSFC 699
Query: 1150 PLSCGDLPVPGGCGSECHEGCVCDEG--FALSGESCLPLASCGCVHQGTYHPPGQTFYPG 1207
SC L P C +C EGC C EG + + C+P+ C C ++G+ + PG+
Sbjct: 700 LHSCISLSSPEQCSDDCAEGCNCPEGKFYEDTLNFCVPIFHCRCHYRGSVYQPGELI--- 756
Query: 1208 PGCDSLCHCQEG----------------------------------GLVSCES--SSCGP 1231
P LC C G G V+CE+ ++
Sbjct: 757 PTPSGLCQCSNGTVKCDELATPSAVHICPEGKEYFDCRFPDPELPAGGVNCETTCANLAM 816
Query: 1232 HEACQPSGGSL-GCVAVGS---------------STCQASGDPHYTTFDGRRFDFMGTCV 1275
+ C PS + GCV + C GD HY +FDG +D++ C
Sbjct: 817 NFTCTPSSPCISGCVCAPGVCRRGMFNCTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQ 876
Query: 1276 YVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVD 1335
L ++ +V+ +N + + ++ + + V + + L +K +G
Sbjct: 877 VFLIKSADDSD----ISVIAQNKKCFDNDIVCSKSVLISVGDTEIYLNDTPYKQKQSGFF 932
Query: 1336 MKLPVVLANGQIRASQHGSDVVIE-TDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYN 1394
++ + + G +V+ + + + +D + + V + ++ GLCGN++
Sbjct: 933 LE-----NKSTYQLWKAGYYIVVYFPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFD 987
Query: 1395 GDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKK 1454
+D N + NA FG+SW +SP PC +K P
Sbjct: 988 KCTSNDMTTSNNLEVRNARVFGDSWALGQCESPDETIKPCE------AHQNKFP------ 1035
Query: 1455 YQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLG--GGNLSILCSNIHAYVSAC 1512
Y K+E C +L S +SC ++D K+C D C GG+ LC++I AY C
Sbjct: 1036 YAKKE-CSILYSDI--FASCRNVIDVTSFAKNCHEDTCNCNLGGDCECLCTSIAAYAYKC 1092
Query: 1513 QAAGGHVEPWRTETFCPMEC 1532
G + WR+ T C ++C
Sbjct: 1093 CQEGISIH-WRSSTVCSLDC 1111
Score = 305 bits (782), Expect = 3e-82
Identities = 307/1192 (25%), Positives = 459/1192 (38%), Gaps = 224/1192 (18%)
Query: 1646 HGVTCRPQETCKEQ-----GGQGVCLPNY----EATCWLWGDPHYHSFDGRKFDFQGTCN 1696
+G C TC Q G + +PN + C WG H+ +FDG + F G C+
Sbjct: 28 NGAFCSKTGTCDCQIFQALGTRCQIIPNMGNGRDGICKTWGQYHFETFDGIYYYFPGNCS 87
Query: 1697 YVLATTGCPGVSTQGLTPFTVTTKNQNR--GNPAVSYVRVVTVAALGTNISIHKDEIGKV 1754
Y+ A C + + +TV N + G+ Y + + I I+ EI K
Sbjct: 88 YIFAKD-CGDLEPR----YTVWVHNSPKCLGSVYSCYRSISLFFSNQEEIRIYGHEIKK- 141
Query: 1755 RVCVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVC 1814
NG+ LP ++ G+I + + A L+ FG +++D + + L + G C
Sbjct: 142 ----NGISLTLPQTI--GQIFIEKLADYILVKTTFGFSLAWDGISGIYLKLSEDHKGKSC 195
Query: 1815 GLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQY 1874
GLCGN + ++D + I ++ SW D C P D
Sbjct: 196 GLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDT-------KCVLTPSD----- 243
Query: 1875 EGPGFCGPLASGTGG--------------PFTTCHAHVPPESFFKGCVLDVCMGGGDRDI 1920
F P +SG PF +CH ++ P + CV D+C D +
Sbjct: 244 ----FPNPCSSGMPAFEAIFFKCQILLQFPFLSCHEYIDPYLYIASCVNDLCKTDDD-ET 298
Query: 1921 LCKALASYVAACQAAGVVIEDWRAQV-GCEITCPENSHYEVCGPPCPASCPSPAPLTTPA 1979
C+A Y AC AG I+DWR C C ++ + C CP +C T
Sbjct: 299 YCRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTC------TFEK 352
Query: 1980 VCEGP---CVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRC 2036
C G C++GC C G V+ C+ L N C C +G + GS+ + C++ C C
Sbjct: 353 QCLGSNLHCLDGCYCPDGLVMDNGTCISLEN-CPCGFHGLAYSVGSKI--EQECTE-CVC 408
Query: 2037 GPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTC 2096
GG CT C PV +C GD H+ T DG + F G C
Sbjct: 409 V--GGVWNCTEQDC-----------------PV---QCSVVGDSHFTTFDGRHYSFIGMC 446
Query: 2097 EYLLSAPCHGPPLGAENFTVTVANEH-RGSQAVSYTRSVTLQI---YNHSLTLSARWPRK 2152
+Y+L G + FT+T+ + + +S+TL + +N +TL
Sbjct: 447 QYILVKGT-----GKDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGR----- 496
Query: 2153 LQVDGVFVALP---FQLDSLLHAH-LSGADVVVTTTSGLSLAF--DGDSFVRLRVPAAYA 2206
G + P F L+ ++ LS +++ TT GL + F DG+ + +++ +A+
Sbjct: 497 ---GGQILTSPNQGFNLNGIVEIQTLSSLFILLKTTFGLKILFAIDGER-IYIQLTSAWK 552
Query: 2207 ASLCGLCGNYNQDPADDLKAVGGKPAG--------WQVGGAQGCGECVSKPCPSPCTPEQ 2258
GLCG +N + DD + G G W+V C V P PC Q
Sbjct: 553 RRTLGLCGTFNGNIRDDFLSPSGMIEGTPQLHANAWRVSST--CFAPVHVPVVDPCNINQ 610
Query: 2259 QESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAA 2318
Q + G C VI APCH + P Y+Q C DAC+ LC A+A Y
Sbjct: 611 Q-NIGYAAHCDVIHQE--LFAPCHIYISPGLYYQLCRHDACKCGS--SCLCNALAHYAYL 665
Query: 2319 CQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAG 2378
C G + + FC + C Y C C SC SLS+PE C C EGC C G
Sbjct: 666 CGQHGVPIDFRTQISFCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEG 725
Query: 2379 --FVLSGDTCVPVGQCGCLHDGRYYPLGEVF----------------------------- 2407
+ + + CVP+ C C + G Y GE+
Sbjct: 726 KFYEDTLNFCVPIFHCRCHYRGSVYQPGELIPTPSGLCQCSNGTVKCDELATPSAVHICP 785
Query: 2408 ---------YPGPE-------CERRC-------ECGPGGHVTCQEGAACGPHEECRLEDG 2444
+P PE CE C C P C G C P CR G
Sbjct: 786 EGKEYFDCRFPDPELPAGGVNCETTCANLAMNFTCTPSS--PCISGCVCAP-GVCR--RG 840
Query: 2445 VQACHATGC-GRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNA 2503
+ C C C G HY + DG YD C L + D D S++ +
Sbjct: 841 MFNCTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLIK----SADDSDISVIAQNKK 896
Query: 2504 AGDLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRN-----------M 2552
D +V ++S+ + D P + E ++ +
Sbjct: 897 CFDND--IVCSKSVLISVGDTEIYLND-----TPYKQKQSGFFLENKSTYQLWKAGYYIV 949
Query: 2553 VLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFG 2612
V K + +L+D + + + ++ +L GLCGNF+ S+D N + FG
Sbjct: 950 VYFPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFG 1009
Query: 2613 AAWRAPGSSKGCGEGCGPQGCPVCLAEETA-PYESNEACGQLRNPQGPFATCQAVLSPSE 2671
+W A G + E P C A + PY E C L + FA+C+ V+ +
Sbjct: 1010 DSW-ALGQCESPDETIKP-----CEAHQNKFPYAKKE-CSILYS--DIFASCRNVIDVTS 1060
Query: 2672 YFRQCVYDLCAQK--GDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHC 2721
+ + C D C GD LC S+AAY C G+++ WR+ + C L C
Sbjct: 1061 FAKNCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIH-WRSSTVCSLDC 1111
Score = 302 bits (774), Expect = 3e-81
Identities = 292/1190 (24%), Positives = 462/1190 (38%), Gaps = 157/1190 (13%)
Query: 820 CQRRCTCNGA--THQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDG 877
C C NGA + TC + G RC + + R G C+ G H+ +FDG
Sbjct: 22 CPYECL-NGAFCSKTGTCDCQIFQALGTRCQIIPNMGN---GRDGICKTWGQYHFETFDG 77
Query: 878 RRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHR--GSQTVSYTRAVRVEARGVKVAVR 935
+ F G C+Y+ CG P + V V N + GS Y + ++ +
Sbjct: 78 IYYYFPGNCSYIFAKDCGDLE--PRYTVWVHNSPKCLGSVYSCYRSISLFFSNQEEIRI- 134
Query: 936 REYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSY 995
Y ++ + + LP GQ+ + + +V+T FG ++ +D + + K+ +
Sbjct: 135 --YGHEIKKNGISLTLP--QTIGQIFIEKLADYILVKTTFGFSLAWDGISGIYLKLSEDH 190
Query: 996 AEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPG--CGATEPGDCPKLDS 1053
CGLCGN+N +DD + + F NSW +T C T P D P S
Sbjct: 191 KGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVLT-PSDFPNPCS 249
Query: 1054 LVAQQLQS-KNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATY 1112
++ +C IL + PF CH +DP + CV D C C A Y
Sbjct: 250 SGMPAFEAIFFKCQILL--QFPFLSCHEYIDPYLYIASCVNDLCKTDDDE-TYCRAATEY 306
Query: 1113 AAACQAAGATVHPWRSE-ELCPLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCV 1171
A AC AG + WR + C C + C CP +C G C +GC
Sbjct: 307 ARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTCTFEKQCLGSNLHCLDGCY 366
Query: 1172 CDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGP 1231
C +G + +C+ L +C C G + G C C C GG+ +C C
Sbjct: 367 CPDGLVMDNGTCISLENCPCGFHGLAYSVGSKI--EQECTE-CVC-VGGVWNCTEQDC-- 420
Query: 1232 HEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRF 1291
C GD H+TTFDGR + F+G C Y+L + GT G +F
Sbjct: 421 -----------------PVQCSVVGDSHFTTFDGRHYSFIGMCQYILVK--GT--GKDKF 459
Query: 1292 AV-LQENVAWGN-GRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRA 1349
+ LQ+ N G V + + + +F ++ + + + + NG +
Sbjct: 460 TITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGRGGQILTSPNQGFNL---NGIVEI 516
Query: 1350 SQHGS-DVVIETDFGLRVAYDL---VYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPN 1405
S ++++T FGL++ + + Y+++T + ++ GLCG +NG+ +DDF P+
Sbjct: 517 QTLSSLFILLKTTFGLKILFAIDGERIYIQLT--SAWKRRTLGLCGTFNGNIRDDFLSPS 574
Query: 1406 GSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLS 1465
G G N+W S C P P I ++ C ++
Sbjct: 575 GMIEGTPQLHANAWR---VSSTCFAPVHVPVVDPCNIN--------QQNIGYAAHCDVIH 623
Query: 1466 SPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTE 1525
+ CH + P + C D C G S LC+ + Y C G ++ +RT+
Sbjct: 624 QEL--FAPCHIYISPGLYYQLCRHDACKCGS--SCLCNALAHYAYLCGQHGVPID-FRTQ 678
Query: 1526 -TFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNG--QACVPI 1582
+FC + C Y C+ C C +LS+P QC D CAEGC C G Y CVPI
Sbjct: 679 ISFCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEGKFYEDTLNFCVPI 738
Query: 1583 QQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQE-------HSCKPGQV---CQ- 1631
C C++ G Y+P + LI C C G + C E H C G+ C+
Sbjct: 739 FHCRCHYRGSVYQPGE--LIPTPSGLCQCSNGT-VKCDELATPSAVHICPEGKEYFDCRF 795
Query: 1632 -----PSGGI------------LSCVTKDPC-HGVTCRPQETCKEQGGQGVCLPNYEATC 1673
P+GG+ +C PC G C P C+ +G A C
Sbjct: 796 PDPELPAGGVNCETTCANLAMNFTCTPSSPCISGCVCAP-GVCR-RGMFNCTYYPCPAVC 853
Query: 1674 WLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVR 1733
++GD HY+SFDG ++D+ C L + + + +V +N+ + + +
Sbjct: 854 TIYGDRHYYSFDGLEYDYISDCQVFL-------IKSADDSDISVIAQNKKCFDNDIVCSK 906
Query: 1734 VVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVADF---- 1789
V ++ T I L P + ++ L A +
Sbjct: 907 SVLISVGDTEI----------------YLNDTPYKQKQSGFFLENKSTYQLWKAGYYIVV 950
Query: 1790 -----GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGG 1844
+ + +D + + + + + GLCGN D+ +ND N + ++G
Sbjct: 951 YFPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGD 1010
Query: 1845 SWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFF 1904
SW +C T Q + P + F +C + SF
Sbjct: 1011 SW--------ALGQCESPDETIKPCEAHQNKFPYAKKECSILYSDIFASCRNVIDVTSFA 1062
Query: 1905 KGCVLDVCMG--GGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITC 1952
K C D C GGD + LC ++A+Y C G+ I WR+ C + C
Sbjct: 1063 KNCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIH-WRSSTVCSLDC 1111
Score = 254 bits (648), Expect = 1e-66
Identities = 226/841 (26%), Positives = 342/841 (40%), Gaps = 99/841 (11%)
Query: 2024 FWADGTCSQWCRCGPGGGSLVCTPASC------GLGEVCGLLPSGQHGCQPVSTAECQAW 2077
F G+C C G+ +C LG C ++P+ +G + C+ W
Sbjct: 16 FSPSGSCPYECL----NGAFCSKTGTCDCQIFQALGTRCQIIPNMGNGRDGI----CKTW 67
Query: 2078 GDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAV-SYTRSVTL 2136
G H+ T DG + F G C Y+ + C +TV V N + +V S RS++L
Sbjct: 68 GQYHFETFDGIYYYFPGNCSYIFAKDCGDLE---PRYTVWVHNSPKCLGSVYSCYRSISL 124
Query: 2137 QIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSF 2196
N + +++ +G+ + LP + + L+ ++V TT G SLA+DG S
Sbjct: 125 FFSNQEEIRI--YGHEIKKNGISLTLPQTIGQIFIEKLADY-ILVKTTFGFSLAWDGISG 181
Query: 2197 VRLRVPAAYAASLCGLCGNYNQDPADDL--------KAVGGKPAGWQVGGAQGCGECVSK 2248
+ L++ + CGLCGNYN +DD + + W V +CV
Sbjct: 182 IYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDT-KCVLT 240
Query: 2249 PC--PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPG 2306
P P+PC+ C ++ P CH + P Y C+ D C+
Sbjct: 241 PSDFPNPCSSGMPAFEAIFFKCQIL--LQFPFLSCHEYIDPYLYIASCVNDLCKTDDDET 298
Query: 2307 GLCPAVATYVAACQAAGAQLGEWRRPDF--CPLQCPAHSHYELCGDSCPVSCPSLSAPEG 2364
C A Y AC AG + +WR DF C +C + C CP +C G
Sbjct: 299 -YCRAATEYARACSHAGYPIQDWR-DDFPACTDKCDDSFVHRDCISCCPPTCTFEKQCLG 356
Query: 2365 CESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGH 2424
C +GC C G V+ TC+ + C C G Y +G + E+ C
Sbjct: 357 SNLHCLDGCYCPDGLVMDNGTCISLENCPCGFHGLAYSVGS------KIEQECT------ 404
Query: 2425 VTCQEGAACGPHEECRLEDGVQACHATGCG-RCLANGGIHYITLDGRVYDLHGSCSYVLA 2483
EC GV C C +C G H+ T DGR Y G C Y+L
Sbjct: 405 -------------ECVCVGGVWNCTEQDCPVQCSVVGDSHFTTFDGRHYSFIGMCQYILV 451
Query: 2484 QVCHPKPGDEDFSIVLEKNAAGD------LQRLLVTVA---GQVVSLAQGQQV-TVDGEA 2533
+ G + F+I L+K LQ + + + + V+L +G Q+ T +
Sbjct: 452 K----GTGKDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGRGGQILTSPNQG 507
Query: 2534 VALPVAVGRVRV-TAEGRNMVLQTTKGLRLLF--DGDAHLLMSIPSPFRGRLCGLCGNFN 2590
L G V + T ++L+TT GL++LF DG+ + + + S ++ R GLCG FN
Sbjct: 508 FNLN---GIVEIQTLSSLFILLKTTFGLKILFAIDGE-RIYIQLTSAWKRRTLGLCGTFN 563
Query: 2591 GNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEAC 2650
GN DDF+ P+G + + AWR SS P P + ++ Y ++ C
Sbjct: 564 GNIRDDFLSPSGMIEGTPQLHANAWRV--SSTCFAPVHVPVVDPCNINQQNIGYAAH--C 619
Query: 2651 GQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKP 2710
+ Q FA C +SP Y++ C +D C K + LC +LA Y C GV +
Sbjct: 620 DVIH--QELFAPCHIYISPGLYYQLCRHDAC--KCGSSCLCNALAHYAYLCGQHGVPIDF 675
Query: 2711 WRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQ--GVC 2768
SFC + C Y C+ C SC +LS C+ C EGC C + C
Sbjct: 676 RTQISFCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEGKFYEDTLNFC 735
Query: 2769 IPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPG-RVCEVKAEARN 2827
+P+ C C + G + T S C CS+ + + C P +C E +
Sbjct: 736 VPIFHCRCHYRGSVYQPGELIPTP--SGLCQCSNGT-VKCDELATPSAVHICPEGKEYFD 792
Query: 2828 C 2828
C
Sbjct: 793 C 793
Score = 201 bits (512), Expect = 7e-51
Identities = 195/769 (25%), Positives = 303/769 (39%), Gaps = 120/769 (15%)
Query: 455 CQVVGGKAGCVAESTAV-CRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSV 513
C VGG C + V C GD H+TTFDGR Y +G C Y +V+ +D
Sbjct: 406 CVCVGGVWNCTEQDCPVQCSVVGDSHFTTFDGRHYSFIGMCQYILVKGTGKDKFTITLQK 465
Query: 514 EAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVD-NQRSRLPVSLSEGRLRVYQ 572
++ G + + L+ ++ V+L RG G +L NQ L + L
Sbjct: 466 APCEQNLGLVCLQSITLILEDDFNKQVTLGRG--GQILTSPNQGFNLNGIVEIQTL---- 519
Query: 573 SGPRAVVELVFGLVVTYDWDCQ-LALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAP 631
S +++ FGL + + D + + + L + ++ + GLCG +NG+ DDFL+P G +
Sbjct: 520 SSLFILLKTTFGLKILFAIDGERIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEG 579
Query: 632 DAVEFASSWKLDDGDYL-----CEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAV 686
A++W++ + D C N G A H C ++ + FA
Sbjct: 580 TPQLHANAWRVSSTCFAPVHVPVVDPCNINQQNI--GYAAH------CDVIHQ--ELFAP 629
Query: 687 CHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPAN-CPLSC 745
CH + P + + C +D C G LC L+ YA C + G+ + D+R+ + C + C
Sbjct: 630 CHIYISPGLYYQLCRHDACKCGSS--CLCNALAHYAYLCGQHGVPI-DFRTQISFCAVVC 686
Query: 746 PANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPG--FVASGGACVPASSCGCTF 803
Y C C SC ++P CS C EGC C G + + CVP C C +
Sbjct: 687 QKGMLYHHCSSFCLHSCISLSSPEQCSD-DCAEGCNCPEGKFYEDTLNFCVPIFHCRCHY 745
Query: 804 QGLQLAPGQ--------------EVWADELCQRRC------------------------- 824
+G PG+ V DEL
Sbjct: 746 RGSVYQPGELIPTPSGLCQCSNGTVKCDELATPSAVHICPEGKEYFDCRFPDPELPAGGV 805
Query: 825 ----TCNGATHQVTCRDKQSCPAGERCS---VQNGLLGC--YPDRFGTCQGSGDPHYVSF 875
TC TC C +G C+ + G+ C YP C GD HY SF
Sbjct: 806 NCETTCANLAMNFTCTPSSPCISGCVCAPGVCRRGMFNCTYYPCP-AVCTIYGDRHYYSF 864
Query: 876 DGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVR 935
DG +D++ C L+ S + V+ +N+ + +++V + ++ +
Sbjct: 865 DGLEYDYISDCQVFLIKSADDSD----ISVIAQNKKCFDNDIVCSKSVLISVGDTEIYLN 920
Query: 936 REYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVR-TDFGLTVTYDWNARVTAKVPSS 994
Q Q F Q+++ G VV + +T+ +D + KV
Sbjct: 921 DTPYKQK------QSGFFLENKSTYQLWKAGYYIVVYFPEKDITILWDRKTTIHIKVGPQ 974
Query: 995 YAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSL 1054
+ L GLCGNF+ ++D+ + NA FG+SW G C D
Sbjct: 975 WKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSW-----------ALGQCESPDET 1023
Query: 1055 V----AQQLQ---SKNECGILADPKGPFRECHSKLDPQGAVRDCVYD--RCLLPGQSGPL 1105
+ A Q + +K EC IL F C + +D ++C D C L G L
Sbjct: 1024 IKPCEAHQNKFPYAKKECSILY--SDIFASCRNVIDVTSFAKNCHEDTCNCNLGGDCECL 1081
Query: 1106 CDALATYAAACQAAGATVHPWRSEELCPLSCPPHSH------YEACSYG 1148
C ++A YA C G ++H WRS +C L C ++ Y SYG
Sbjct: 1082 CTSIAAYAYKCCQEGISIH-WRSSTVCSLDCEYYNEGLGEGPYMLASYG 1129
Score = 85.9 bits (211), Expect = 6e-16
Identities = 98/406 (24%), Positives = 143/406 (35%), Gaps = 47/406 (11%)
Query: 464 CVAESTAVCRAQ--GDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRG 521
C E CR + TFDG + SY +V + E + A +
Sbjct: 1431 CCPEWECPCRCSMLSELSIITFDGNNAALYSMASYILVRIPGE--IIVAHIEKCSMNQAP 1488
Query: 522 SRRVSYVGL--VTVRAYSHSVSLTR----GEVGFVLVDNQRSRLPVSLSEGRLRVYQSGP 575
S R+S + + V H + + R EV ++V P+ S L + SG
Sbjct: 1489 SGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVV-------PLPFSSQELSIEDSGS 1541
Query: 576 RAVVELVFGLVVTYDW---DCQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAPD 632
V+ GL++ + + GLCG N DP DD +G + +
Sbjct: 1542 MYVITTPAGLIIKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTIITN 1601
Query: 633 AVE---FASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHD 689
+ F SW+++ + NC Q R+ F CHD
Sbjct: 1602 MEDIGLFIESWEIEKSFEVTMRRPVRNCTEHDCSQCIDLLNRRI----------FIPCHD 1651
Query: 690 TLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSCPANS 749
+ P F E+ + C LSAY C + I + WR+P C LSCP
Sbjct: 1652 KVSPEDFCEKMWINYTYFWNYE---CDALSAYVALCNKFDICI-QWRTPDYCSLSCPEGK 1707
Query: 750 RYELCGPACPT-SCNGAAAPSNCSGRPCVEGCVCLPGFV---ASGGACVPASSCGCTFQG 805
Y+ C C +C + S E CVC G V C+P C CT
Sbjct: 1708 EYQPCVRPCEARTCLNQWFYGHTSCLNLREDCVCKVGTVLHRPHSAQCIPEKECACTDSE 1767
Query: 806 LQLAPGQEVW---ADELCQRRCTCNGATHQV--TCRDKQSCPAGER 846
Q E+W DE +C NG+ + C D++ P ER
Sbjct: 1768 DQPRTAGEIWNGGIDECTLYKCLENGSIIPIEPDC-DEEPTPVCER 1812
Score = 79.0 bits (193), Expect = 7e-14
Identities = 95/400 (23%), Positives = 146/400 (36%), Gaps = 56/400 (14%)
Query: 864 CQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAV 923
C + ++FDG +Y+LV G+ + + G + + +
Sbjct: 1441 CSMLSELSIITFDGNNAALYSMASYILVRIPGEIIVAHIEKCSMNQAPSGRISGLCFKKL 1500
Query: 924 RVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDW 983
V K+ V R +V VD ++ LPF + + ++ G V+ T GL + +
Sbjct: 1501 NVTTPIHKIIVNR-LARKVEVDSIVVPLPFSSQELSIE--DSGSMYVITTPAGLIIKW-- 1555
Query: 984 NARVTAKVP---------SSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFG---NS 1031
+ +T + SSY E LCG+C N DP DDL ++ G N G S
Sbjct: 1556 -SHLTGIIDIHFGFRFNLSSYTEGLCGIC---NEDPDDDLRMQNGTIITNMEDIGLFIES 1611
Query: 1032 WQEET-------RPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDP 1084
W+ E RP TE DC + L+ +++ F CH K+ P
Sbjct: 1612 WEIEKSFEVTMRRPVRNCTEH-DCSQCIDLLNRRI---------------FIPCHDKVSP 1655
Query: 1085 QGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEA 1144
+ + CDAL+ Y A C + WR+ + C LSCP Y+
Sbjct: 1656 EDFCEKMWINYTYFWNYE---CDALSAYVALCNKFDICIQ-WRTPDYCSLSCPEGKEYQP 1711
Query: 1145 CSYGCPL-SCGDLPVPGGCGS-ECHEGCVCDEGFAL---SGESCLPLASCGCV-HQGTYH 1198
C C +C + G E CVC G L C+P C C +
Sbjct: 1712 CVRPCEARTCLNQWFYGHTSCLNLREDCVCKVGTVLHRPHSAQCIPEKECACTDSEDQPR 1771
Query: 1199 PPGQTFYPGPGCDSLCHCQEGGLVSCESSSCG--PHEACQ 1236
G+ + G +L C E G + C P C+
Sbjct: 1772 TAGEIWNGGIDECTLYKCLENGSIIPIEPDCDEEPTPVCE 1811
Score = 78.6 bits (192), Expect = 9e-14
Identities = 100/440 (22%), Positives = 165/440 (37%), Gaps = 73/440 (16%)
Query: 2418 ECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGS 2477
+CG G C P EC RC + IT DG L+
Sbjct: 1416 DCGFRGRPVQVNSDICCPEWECPC-------------RCSMLSELSIITFDGNNAALYSM 1462
Query: 2478 CSYVLAQVCHPKPGDEDFSIV----LEKNAAGDLQRL------LVTVAGQVVSLAQGQQV 2527
SY+L ++ PG+ + + + + +G + L + T +++ ++V
Sbjct: 1463 ASYILVRI----PGEIIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLARKV 1518
Query: 2528 TVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHL--LMSIPSPFRGRLC-- 2583
VD V LP + + + G V+ T GL + + +HL ++ I FR L
Sbjct: 1519 EVDSIVVPLPFSSQELSIEDSGSMYVITTPAGLIIKW---SHLTGIIDIHFGFRFNLSSY 1575
Query: 2584 --GLCGNFNGNWSDDFVLPNGSAASSVETFGA---AWRAPGS----SKGCGEGCGPQGCP 2634
GLCG N + DD + NG+ +++E G +W S + C C
Sbjct: 1576 TEGLCGICNEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTMRRPVRNCTEHDCS 1635
Query: 2635 VCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSL 2694
C+ L N + F C +SP ++ + + + C +L
Sbjct: 1636 QCI--------------DLLNRR-IFIPCHDKVSPEDFCEKMWINYTYFWN---YECDAL 1677
Query: 2695 AAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTT--RCF 2752
+AY A C + ++ WRT +C L CP Y C R C+ G T+
Sbjct: 1678 SAYVALCNKFDICIQ-WRTPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSCLNLR 1736
Query: 2753 EGCECDDRFLLSQ---GVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCS---CSSSSGL 2806
E C C +L + CIP ++C CT + P + + + + C+ C + +
Sbjct: 1737 EDCVCKVGTVLHRPHSAQCIPEKECACT-DSEDQPRTAGEIWNGGIDECTLYKCLENGSI 1795
Query: 2807 TCQAAGC--PPGRVCEVKAE 2824
C P VCE +AE
Sbjct: 1796 IPIEPDCDEEPTPVCEREAE 1815
Score = 78.2 bits (191), Expect = 1e-13
Identities = 88/345 (25%), Positives = 130/345 (37%), Gaps = 46/345 (13%)
Query: 2074 CQAWGDPHYVTLDGHRFDFQGTCEYLL-SAPCHGPPLGAENFTVTVANEHRGSQAVSYTR 2132
C + +T DG+ Y+L P E ++ A R S
Sbjct: 1441 CSMLSELSIITFDGNNAALYSMASYILVRIPGEIIVAHIEKCSMNQAPSGRISGLCFKKL 1500
Query: 2133 SVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFD 2192
+VT I H + ++ R RK++VD + V LPF L SG+ V+TT +GL + +
Sbjct: 1501 NVTTPI--HKIIVN-RLARKVEVDSIVVPLPFSSQEL-SIEDSGSMYVITTPAGLIIKWS 1556
Query: 2193 G-----DSFVRLRVP-AAYAASLCGLCGNYNQDPADDLKAVGGKPA-----------GWQ 2235
D R ++Y LCG+C N+DP DDL+ G W+
Sbjct: 1557 HLTGIIDIHFGFRFNLSSYTEGLCGIC---NEDPDDDLRMQNGTIITNMEDIGLFIESWE 1613
Query: 2236 VGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPL-APCHGLVPPAQYFQGC 2294
+ + E + CT D I + + PCH V P + +
Sbjct: 1614 I---EKSFEVTMRRPVRNCTEH--------DCSQCIDLLNRRIFIPCHDKVSPEDFCEKM 1662
Query: 2295 LLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPV 2354
++ + C A++ YVA C + +WR PD+C L CP Y+ C C
Sbjct: 1663 WINYTYFWNYE---CDALSAYVALCNKFDICI-QWRTPDYCSLSCPEGKEYQPCVRPCEA 1718
Query: 2355 SCPSLSAPEGCESA--CREGCVCDAGFVL---SGDTCVPVGQCGC 2394
G S RE CVC G VL C+P +C C
Sbjct: 1719 RTCLNQWFYGHTSCLNLREDCVCKVGTVLHRPHSAQCIPEKECAC 1763
Score = 65.9 bits (159), Expect = 6e-10
Identities = 90/390 (23%), Positives = 144/390 (36%), Gaps = 54/390 (13%)
Query: 1659 QGGQGVCLPNYEATCW--LWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFT 1716
Q +C P +E C + + +FDG +Y+L PG
Sbjct: 1425 QVNSDICCPEWECPCRCSMLSELSIITFDGNNAALYSMASYILVRI--PG-------EII 1475
Query: 1717 VTTKNQNRGNPAVS-YVRVVTVAALGTNISIHKDEIGKV--RVCVNGVLTALPVSVADGR 1773
V + N A S + + L IHK + ++ +V V+ ++ LP S +
Sbjct: 1476 VAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQE-- 1533
Query: 1774 ISVAQGASKALLVADFGLQVSYD---------WNWRVDVTLPSSYHGAVCGLCGNMDRNP 1824
+S+ S ++ GL + + + +R ++ SSY +CG+C + +P
Sbjct: 1534 LSIEDSGSMYVITTPAGLIIKWSHLTGIIDIHFGFRFNL---SSYTEGLCGIC---NEDP 1587
Query: 1825 NNDQVFPNGTLAPS---IPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCG 1881
++D NGT+ + I ++ SW + R C E Q C
Sbjct: 1588 DDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTM---RRPVRNCTEHDCSQ------CI 1638
Query: 1882 PLASGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIED 1941
L + F CH V PE F + ++ C AL++YVA C + I+
Sbjct: 1639 DLLNRR--IFIPCHDKVSPEDFCEKMWINYTYFWNYE---CDALSAYVALCNKFDICIQ- 1692
Query: 1942 WRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVL---S 1998
WR C ++CPE Y+ C PC A C E C C G VL
Sbjct: 1693 WRTPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSCLN-LREDCVCKVGTVLHRPH 1751
Query: 1999 ADRCVPLNNGCGCWANGTYHEAGSEFWADG 2028
+ +C+P C C + E W G
Sbjct: 1752 SAQCIP-EKECACTDSEDQPRTAGEIWNGG 1780
Score = 58.9 bits (141), Expect = 7e-08
Identities = 112/530 (21%), Positives = 177/530 (33%), Gaps = 113/530 (21%)
Query: 1126 WRSEELCPLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGF--ALSGESC 1183
WR E C C ++ CS L+C LP GC C + + DE + C
Sbjct: 1279 WRYEP-CATPC-----FKTCSDPEALACKFLPPVEGCLPYCPKNMILDEVTLKCVYPRDC 1332
Query: 1184 LPLASCGCVHQGTYHPPGQTFYP-----------------------GPGC-----DSLCH 1215
+P+ + T PP + P G C D +
Sbjct: 1333 IPVIPT----EPTLMPPAKPTVPMFTVWEMITPSDITVFDMLTPTTGLECEPQKFDPVYD 1388
Query: 1216 CQEGGLVSCE------SSSCGPHEACQPSGGSLG---------CVAVGSSTCQAS--GDP 1258
C + ++ E S +C P + P G G C C+ S +
Sbjct: 1389 CSQYICLNMEWQLYNWSLNC-PKDVEMPDCGFRGRPVQVNSDICCPEWECPCRCSMLSEL 1447
Query: 1259 HYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANF 1318
TFDG Y+L + G H G + + V
Sbjct: 1448 SIITFDGNNAALYSMASYILVRIPGEIIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIH 1507
Query: 1319 TLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAY-------DLV 1371
+ + + KV V+ + + LP ++ ++ GS VI T GL + + D+
Sbjct: 1508 KIIVNRLARKVEVDSIVVPLP--FSSQELSIEDSGSMYVITTPAGLIIKWSHLTGIIDIH 1565
Query: 1372 YYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFG---NSWE-----EVV 1423
+ R + +Y + +CG+C N DP DD + NG+ N + G SWE EV
Sbjct: 1566 FGFRFNL-SSYTEGLCGIC---NEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVT 1621
Query: 1424 PDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGP 1483
P T DC +C L ++ CH V P+
Sbjct: 1622 MRRPVRNCT-----EHDC---SQCIDLLNRRI---------------FIPCHDKVSPEDF 1658
Query: 1484 LKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCAD 1543
+ + + C + AYV+ C ++ WRT +C + CP Y+ C
Sbjct: 1659 CEKMWINYTYFW---NYECDALSAYVALCNKFDICIQ-WRTPDYCSLSCPEGKEYQPCVR 1714
Query: 1544 TCSLGCSALSAPPQCQDGC---AEGCQCDSGFLY---NGQACVPIQQCGC 1587
C + L+ C E C C G + + C+P ++C C
Sbjct: 1715 PCE-ARTCLNQWFYGHTSCLNLREDCVCKVGTVLHRPHSAQCIPEKECAC 1763
Score = 47.0 bits (110), Expect = 3e-04
Identities = 50/204 (24%), Positives = 83/204 (40%), Gaps = 22/204 (10%)
Query: 2793 DCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGA 2852
+C CS + CQ G C++ N G+C + TFDG
Sbjct: 25 ECLNGAFCSKTGTCDCQIFQAL-GTRCQIIPNMGN--GRDGICKTWGQYHFETFDGIYYY 81
Query: 2853 TTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVGQVH-------IFFQDGMVTL 2905
Y + C L+ P Y V H + +G V+ +FF +
Sbjct: 82 FPGNCSYIFAKDCGDLE---PRYTVWV-----HNSPKCLGSVYSCYRSISLFFSNQEEIR 133
Query: 2906 TPNKGVWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQV-WLGANGKVAVIVSNDH 2964
+ NG+ + LP + + + + + D +LV+ G + W G +G + + +S DH
Sbjct: 134 IYGHEIKKNGISLTLP-QTIGQIFIEKLAD-YILVKTTFGFSLAWDGISG-IYLKLSEDH 190
Query: 2965 AGKLCGACGNFDGDQTNDWHDSQE 2988
GK CG CGN++ Q++D+ QE
Sbjct: 191 KGKSCGLCGNYNDIQSDDFIILQE 214
>gi|239750386 PREDICTED: chromosome 12 open reading frame 64 [Homo
sapiens]
Length = 2250
Score = 319 bits (818), Expect = 2e-86
Identities = 290/1160 (25%), Positives = 472/1160 (40%), Gaps = 170/1160 (14%)
Query: 450 AAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLP 509
A G RCQ++ +C+ G H+ TFDG Y G CSY + C D P
Sbjct: 45 ALGTRCQIIPNMGN---GRDGICKTWGQYHFETFDGIYYYFPGNCSYIFAKDCG--DLEP 99
Query: 510 AFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSL---TRGEVGFVLVDNQRSRLPVSLSE- 565
++V N + L +V + S+SL + E+ + +++ + ++L +
Sbjct: 100 RYTVWVHNSPKC--------LGSVYSCYRSISLFFSNQEEIRIYGHEIKKNGISLTLPQT 151
Query: 566 -GRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLT 624
G++ + + +V+ FG + +D + L L + + CGLCGNYN +DDF+
Sbjct: 152 IGQIFIEKLADYILVKTTFGFSLAWDGISGIYLKLSEDHKGKSCGLCGNYNDIQSDDFII 211
Query: 625 PDGALAPDAVEFASSWKLDDGD----YLCEDGCQNNCPACTPG-QAQHYEGDRLCGMLTK 679
D FA+SW + D L N C + P +A ++ C +L
Sbjct: 212 LQEDYTEDIAMFANSWSVQTPDDTKCVLTPSDFPNPCSSGMPAFEAIFFK----CQIL-- 265
Query: 680 LDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRS-- 737
L PF CH+ +DP ++ CV DLC + + CR + YA+AC G + DWR
Sbjct: 266 LQFPFLSCHEYIDPYLYIASCVNDLCKTDDDE-TYCRAATEYARACSHAGYPIQDWRDDF 324
Query: 738 PANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGR--PCVEGCVCLPGFVASGGACVP 795
PA C C + + C CP +C C G C++GC C G V G C+
Sbjct: 325 PA-CTDKCDDSFVHRDCISCCPPTC---TFEKQCLGSNLHCLDGCYCPDGLVMDNGTCIS 380
Query: 796 ASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLG 855
+C C F GL + G ++ ++ C C C G T +Q CP +CSV
Sbjct: 381 LENCPCGFHGLAYSVGSKI--EQEC-TECVCVGGVWNCT---EQDCPV--QCSV------ 426
Query: 856 CYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQ 915
GD H+ +FDGR + F+G C Y+LV G++ + ++ G
Sbjct: 427 -----------VGDSHFTTFDGRHYSFIGMCQYILVKGTGKDKFTITLQKAPCEQNLGLV 475
Query: 916 TVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQA--ADGQVQV-FRQGRDAVVR 972
+ + + +V + R GQ+L P Q +G V++ +++
Sbjct: 476 CLQSITLILEDDFNKQVTLGR--GGQILTS------PNQGFNLNGIVEIQTLSSLFILLK 527
Query: 973 TDFGLTVTYDWNA-RVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNS 1031
T FGL + + + R+ ++ S++ GLCG FNG+ DD G N+
Sbjct: 528 TTFGLKILFAIDGERIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEGTPQLHANA 587
Query: 1032 WQEETRPGCGATEPGDCPKLD--SLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVR 1089
W+ + C A P P +D ++ Q + C ++ F CH + P +
Sbjct: 588 WRVSST--CFA--PVHVPVVDPCNINQQNIGYAAHCDVIHQEL--FAPCHIYISPGLYYQ 641
Query: 1090 DCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGC 1149
C +D C S LC+ALA YA C G + C + C Y CS C
Sbjct: 642 LCRHDACKC--GSSCLCNALAHYAYLCGQHGVPIDFRTQISFCAVVCQKGMLYHHCSSFC 699
Query: 1150 PLSCGDLPVPGGCGSECHEGCVCDEG--FALSGESCLPLASCGCVHQGTYHPPGQTFYPG 1207
SC L P C +C EGC C EG + + C+P+ C C ++G+ + PG+
Sbjct: 700 LHSCISLSSPEQCSDDCAEGCNCPEGKFYEDTLNFCVPIFHCRCHYRGSVYQPGELI--- 756
Query: 1208 PGCDSLCHCQEG----------------------------------GLVSCES--SSCGP 1231
P LC C G G V+CE+ ++
Sbjct: 757 PTPSGLCQCSNGTVKCDELATPSAVHICPEGKEYFDCRFPDPELPAGGVNCETTCANLAM 816
Query: 1232 HEACQPSGGSL-GCVAVGS---------------STCQASGDPHYTTFDGRRFDFMGTCV 1275
+ C PS + GCV + C GD HY +FDG +D++ C
Sbjct: 817 NFTCTPSSPCISGCVCAPGVCRRGMFNCTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQ 876
Query: 1276 YVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVD 1335
L ++ +V+ +N + + ++ + + V + + L +K +G
Sbjct: 877 VFLIKSADDSD----ISVIAQNKKCFDNDIVCSKSVLISVGDTEIYLNDTPYKQKQSGFF 932
Query: 1336 MKLPVVLANGQIRASQHGSDVVIE-TDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYN 1394
++ + + G +V+ + + + +D + + V + ++ GLCGN++
Sbjct: 933 LE-----NKSTYQLWKAGYYIVVYFPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFD 987
Query: 1395 GDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKK 1454
+D N + NA FG+SW +SP PC +K P
Sbjct: 988 KCTSNDMTTSNNLEVRNARVFGDSWALGQCESPDETIKPCE------AHQNKFP------ 1035
Query: 1455 YQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLG--GGNLSILCSNIHAYVSAC 1512
Y K+E C +L S +SC ++D K+C D C GG+ LC++I AY C
Sbjct: 1036 YAKKE-CSILYSDI--FASCRNVIDVTSFAKNCHEDTCNCNLGGDCECLCTSIAAYAYKC 1092
Query: 1513 QAAGGHVEPWRTETFCPMEC 1532
G + WR+ T C ++C
Sbjct: 1093 CQEGISIH-WRSSTVCSLDC 1111
Score = 305 bits (782), Expect = 3e-82
Identities = 307/1192 (25%), Positives = 459/1192 (38%), Gaps = 224/1192 (18%)
Query: 1646 HGVTCRPQETCKEQ-----GGQGVCLPNY----EATCWLWGDPHYHSFDGRKFDFQGTCN 1696
+G C TC Q G + +PN + C WG H+ +FDG + F G C+
Sbjct: 28 NGAFCSKTGTCDCQIFQALGTRCQIIPNMGNGRDGICKTWGQYHFETFDGIYYYFPGNCS 87
Query: 1697 YVLATTGCPGVSTQGLTPFTVTTKNQNR--GNPAVSYVRVVTVAALGTNISIHKDEIGKV 1754
Y+ A C + + +TV N + G+ Y + + I I+ EI K
Sbjct: 88 YIFAKD-CGDLEPR----YTVWVHNSPKCLGSVYSCYRSISLFFSNQEEIRIYGHEIKK- 141
Query: 1755 RVCVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVC 1814
NG+ LP ++ G+I + + A L+ FG +++D + + L + G C
Sbjct: 142 ----NGISLTLPQTI--GQIFIEKLADYILVKTTFGFSLAWDGISGIYLKLSEDHKGKSC 195
Query: 1815 GLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQY 1874
GLCGN + ++D + I ++ SW D C P D
Sbjct: 196 GLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDT-------KCVLTPSD----- 243
Query: 1875 EGPGFCGPLASGTGG--------------PFTTCHAHVPPESFFKGCVLDVCMGGGDRDI 1920
F P +SG PF +CH ++ P + CV D+C D +
Sbjct: 244 ----FPNPCSSGMPAFEAIFFKCQILLQFPFLSCHEYIDPYLYIASCVNDLCKTDDD-ET 298
Query: 1921 LCKALASYVAACQAAGVVIEDWRAQV-GCEITCPENSHYEVCGPPCPASCPSPAPLTTPA 1979
C+A Y AC AG I+DWR C C ++ + C CP +C T
Sbjct: 299 YCRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTC------TFEK 352
Query: 1980 VCEGP---CVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRC 2036
C G C++GC C G V+ C+ L N C C +G + GS+ + C++ C C
Sbjct: 353 QCLGSNLHCLDGCYCPDGLVMDNGTCISLEN-CPCGFHGLAYSVGSKI--EQECTE-CVC 408
Query: 2037 GPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTC 2096
GG CT C PV +C GD H+ T DG + F G C
Sbjct: 409 V--GGVWNCTEQDC-----------------PV---QCSVVGDSHFTTFDGRHYSFIGMC 446
Query: 2097 EYLLSAPCHGPPLGAENFTVTVANEH-RGSQAVSYTRSVTLQI---YNHSLTLSARWPRK 2152
+Y+L G + FT+T+ + + +S+TL + +N +TL
Sbjct: 447 QYILVKGT-----GKDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGR----- 496
Query: 2153 LQVDGVFVALP---FQLDSLLHAH-LSGADVVVTTTSGLSLAF--DGDSFVRLRVPAAYA 2206
G + P F L+ ++ LS +++ TT GL + F DG+ + +++ +A+
Sbjct: 497 ---GGQILTSPNQGFNLNGIVEIQTLSSLFILLKTTFGLKILFAIDGER-IYIQLTSAWK 552
Query: 2207 ASLCGLCGNYNQDPADDLKAVGGKPAG--------WQVGGAQGCGECVSKPCPSPCTPEQ 2258
GLCG +N + DD + G G W+V C V P PC Q
Sbjct: 553 RRTLGLCGTFNGNIRDDFLSPSGMIEGTPQLHANAWRVSST--CFAPVHVPVVDPCNINQ 610
Query: 2259 QESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAA 2318
Q + G C VI APCH + P Y+Q C DAC+ LC A+A Y
Sbjct: 611 Q-NIGYAAHCDVIHQE--LFAPCHIYISPGLYYQLCRHDACKCGS--SCLCNALAHYAYL 665
Query: 2319 CQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAG 2378
C G + + FC + C Y C C SC SLS+PE C C EGC C G
Sbjct: 666 CGQHGVPIDFRTQISFCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEG 725
Query: 2379 --FVLSGDTCVPVGQCGCLHDGRYYPLGEVF----------------------------- 2407
+ + + CVP+ C C + G Y GE+
Sbjct: 726 KFYEDTLNFCVPIFHCRCHYRGSVYQPGELIPTPSGLCQCSNGTVKCDELATPSAVHICP 785
Query: 2408 ---------YPGPE-------CERRC-------ECGPGGHVTCQEGAACGPHEECRLEDG 2444
+P PE CE C C P C G C P CR G
Sbjct: 786 EGKEYFDCRFPDPELPAGGVNCETTCANLAMNFTCTPSS--PCISGCVCAP-GVCR--RG 840
Query: 2445 VQACHATGC-GRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNA 2503
+ C C C G HY + DG YD C L + D D S++ +
Sbjct: 841 MFNCTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLIK----SADDSDISVIAQNKK 896
Query: 2504 AGDLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRN-----------M 2552
D +V ++S+ + D P + E ++ +
Sbjct: 897 CFDND--IVCSKSVLISVGDTEIYLND-----TPYKQKQSGFFLENKSTYQLWKAGYYIV 949
Query: 2553 VLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFG 2612
V K + +L+D + + + ++ +L GLCGNF+ S+D N + FG
Sbjct: 950 VYFPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFG 1009
Query: 2613 AAWRAPGSSKGCGEGCGPQGCPVCLAEETA-PYESNEACGQLRNPQGPFATCQAVLSPSE 2671
+W A G + E P C A + PY E C L + FA+C+ V+ +
Sbjct: 1010 DSW-ALGQCESPDETIKP-----CEAHQNKFPYAKKE-CSILYS--DIFASCRNVIDVTS 1060
Query: 2672 YFRQCVYDLCAQK--GDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHC 2721
+ + C D C GD LC S+AAY C G+++ WR+ + C L C
Sbjct: 1061 FAKNCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIH-WRSSTVCSLDC 1111
Score = 302 bits (774), Expect = 3e-81
Identities = 292/1190 (24%), Positives = 462/1190 (38%), Gaps = 157/1190 (13%)
Query: 820 CQRRCTCNGA--THQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDG 877
C C NGA + TC + G RC + + R G C+ G H+ +FDG
Sbjct: 22 CPYECL-NGAFCSKTGTCDCQIFQALGTRCQIIPNMGN---GRDGICKTWGQYHFETFDG 77
Query: 878 RRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHR--GSQTVSYTRAVRVEARGVKVAVR 935
+ F G C+Y+ CG P + V V N + GS Y + ++ +
Sbjct: 78 IYYYFPGNCSYIFAKDCGDLE--PRYTVWVHNSPKCLGSVYSCYRSISLFFSNQEEIRI- 134
Query: 936 REYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSY 995
Y ++ + + LP GQ+ + + +V+T FG ++ +D + + K+ +
Sbjct: 135 --YGHEIKKNGISLTLP--QTIGQIFIEKLADYILVKTTFGFSLAWDGISGIYLKLSEDH 190
Query: 996 AEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPG--CGATEPGDCPKLDS 1053
CGLCGN+N +DD + + F NSW +T C T P D P S
Sbjct: 191 KGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVLT-PSDFPNPCS 249
Query: 1054 LVAQQLQS-KNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATY 1112
++ +C IL + PF CH +DP + CV D C C A Y
Sbjct: 250 SGMPAFEAIFFKCQILL--QFPFLSCHEYIDPYLYIASCVNDLCKTDDDE-TYCRAATEY 306
Query: 1113 AAACQAAGATVHPWRSE-ELCPLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCV 1171
A AC AG + WR + C C + C CP +C G C +GC
Sbjct: 307 ARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTCTFEKQCLGSNLHCLDGCY 366
Query: 1172 CDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGP 1231
C +G + +C+ L +C C G + G C C C GG+ +C C
Sbjct: 367 CPDGLVMDNGTCISLENCPCGFHGLAYSVGSKI--EQECTE-CVC-VGGVWNCTEQDC-- 420
Query: 1232 HEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRF 1291
C GD H+TTFDGR + F+G C Y+L + GT G +F
Sbjct: 421 -----------------PVQCSVVGDSHFTTFDGRHYSFIGMCQYILVK--GT--GKDKF 459
Query: 1292 AV-LQENVAWGN-GRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRA 1349
+ LQ+ N G V + + + +F ++ + + + + NG +
Sbjct: 460 TITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGRGGQILTSPNQGFNL---NGIVEI 516
Query: 1350 SQHGS-DVVIETDFGLRVAYDL---VYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPN 1405
S ++++T FGL++ + + Y+++T + ++ GLCG +NG+ +DDF P+
Sbjct: 517 QTLSSLFILLKTTFGLKILFAIDGERIYIQLT--SAWKRRTLGLCGTFNGNIRDDFLSPS 574
Query: 1406 GSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLS 1465
G G N+W S C P P I ++ C ++
Sbjct: 575 GMIEGTPQLHANAWR---VSSTCFAPVHVPVVDPCNIN--------QQNIGYAAHCDVIH 623
Query: 1466 SPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTE 1525
+ CH + P + C D C G S LC+ + Y C G ++ +RT+
Sbjct: 624 QEL--FAPCHIYISPGLYYQLCRHDACKCGS--SCLCNALAHYAYLCGQHGVPID-FRTQ 678
Query: 1526 -TFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNG--QACVPI 1582
+FC + C Y C+ C C +LS+P QC D CAEGC C G Y CVPI
Sbjct: 679 ISFCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEGKFYEDTLNFCVPI 738
Query: 1583 QQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQE-------HSCKPGQV---CQ- 1631
C C++ G Y+P + LI C C G + C E H C G+ C+
Sbjct: 739 FHCRCHYRGSVYQPGE--LIPTPSGLCQCSNGT-VKCDELATPSAVHICPEGKEYFDCRF 795
Query: 1632 -----PSGGI------------LSCVTKDPC-HGVTCRPQETCKEQGGQGVCLPNYEATC 1673
P+GG+ +C PC G C P C+ +G A C
Sbjct: 796 PDPELPAGGVNCETTCANLAMNFTCTPSSPCISGCVCAP-GVCR-RGMFNCTYYPCPAVC 853
Query: 1674 WLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVR 1733
++GD HY+SFDG ++D+ C L + + + +V +N+ + + +
Sbjct: 854 TIYGDRHYYSFDGLEYDYISDCQVFL-------IKSADDSDISVIAQNKKCFDNDIVCSK 906
Query: 1734 VVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVADF---- 1789
V ++ T I L P + ++ L A +
Sbjct: 907 SVLISVGDTEI----------------YLNDTPYKQKQSGFFLENKSTYQLWKAGYYIVV 950
Query: 1790 -----GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGG 1844
+ + +D + + + + + GLCGN D+ +ND N + ++G
Sbjct: 951 YFPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGD 1010
Query: 1845 SWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFF 1904
SW +C T Q + P + F +C + SF
Sbjct: 1011 SW--------ALGQCESPDETIKPCEAHQNKFPYAKKECSILYSDIFASCRNVIDVTSFA 1062
Query: 1905 KGCVLDVCMG--GGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITC 1952
K C D C GGD + LC ++A+Y C G+ I WR+ C + C
Sbjct: 1063 KNCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIH-WRSSTVCSLDC 1111
Score = 254 bits (648), Expect = 1e-66
Identities = 226/841 (26%), Positives = 342/841 (40%), Gaps = 99/841 (11%)
Query: 2024 FWADGTCSQWCRCGPGGGSLVCTPASC------GLGEVCGLLPSGQHGCQPVSTAECQAW 2077
F G+C C G+ +C LG C ++P+ +G + C+ W
Sbjct: 16 FSPSGSCPYECL----NGAFCSKTGTCDCQIFQALGTRCQIIPNMGNGRDGI----CKTW 67
Query: 2078 GDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAV-SYTRSVTL 2136
G H+ T DG + F G C Y+ + C +TV V N + +V S RS++L
Sbjct: 68 GQYHFETFDGIYYYFPGNCSYIFAKDCGDLE---PRYTVWVHNSPKCLGSVYSCYRSISL 124
Query: 2137 QIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSF 2196
N + +++ +G+ + LP + + L+ ++V TT G SLA+DG S
Sbjct: 125 FFSNQEEIRI--YGHEIKKNGISLTLPQTIGQIFIEKLADY-ILVKTTFGFSLAWDGISG 181
Query: 2197 VRLRVPAAYAASLCGLCGNYNQDPADDL--------KAVGGKPAGWQVGGAQGCGECVSK 2248
+ L++ + CGLCGNYN +DD + + W V +CV
Sbjct: 182 IYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDT-KCVLT 240
Query: 2249 PC--PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPG 2306
P P+PC+ C ++ P CH + P Y C+ D C+
Sbjct: 241 PSDFPNPCSSGMPAFEAIFFKCQIL--LQFPFLSCHEYIDPYLYIASCVNDLCKTDDDET 298
Query: 2307 GLCPAVATYVAACQAAGAQLGEWRRPDF--CPLQCPAHSHYELCGDSCPVSCPSLSAPEG 2364
C A Y AC AG + +WR DF C +C + C CP +C G
Sbjct: 299 -YCRAATEYARACSHAGYPIQDWR-DDFPACTDKCDDSFVHRDCISCCPPTCTFEKQCLG 356
Query: 2365 CESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGH 2424
C +GC C G V+ TC+ + C C G Y +G + E+ C
Sbjct: 357 SNLHCLDGCYCPDGLVMDNGTCISLENCPCGFHGLAYSVGS------KIEQECT------ 404
Query: 2425 VTCQEGAACGPHEECRLEDGVQACHATGCG-RCLANGGIHYITLDGRVYDLHGSCSYVLA 2483
EC GV C C +C G H+ T DGR Y G C Y+L
Sbjct: 405 -------------ECVCVGGVWNCTEQDCPVQCSVVGDSHFTTFDGRHYSFIGMCQYILV 451
Query: 2484 QVCHPKPGDEDFSIVLEKNAAGD------LQRLLVTVA---GQVVSLAQGQQV-TVDGEA 2533
+ G + F+I L+K LQ + + + + V+L +G Q+ T +
Sbjct: 452 K----GTGKDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGRGGQILTSPNQG 507
Query: 2534 VALPVAVGRVRV-TAEGRNMVLQTTKGLRLLF--DGDAHLLMSIPSPFRGRLCGLCGNFN 2590
L G V + T ++L+TT GL++LF DG+ + + + S ++ R GLCG FN
Sbjct: 508 FNLN---GIVEIQTLSSLFILLKTTFGLKILFAIDGE-RIYIQLTSAWKRRTLGLCGTFN 563
Query: 2591 GNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEAC 2650
GN DDF+ P+G + + AWR SS P P + ++ Y ++ C
Sbjct: 564 GNIRDDFLSPSGMIEGTPQLHANAWRV--SSTCFAPVHVPVVDPCNINQQNIGYAAH--C 619
Query: 2651 GQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKP 2710
+ Q FA C +SP Y++ C +D C K + LC +LA Y C GV +
Sbjct: 620 DVIH--QELFAPCHIYISPGLYYQLCRHDAC--KCGSSCLCNALAHYAYLCGQHGVPIDF 675
Query: 2711 WRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQ--GVC 2768
SFC + C Y C+ C SC +LS C+ C EGC C + C
Sbjct: 676 RTQISFCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEGKFYEDTLNFC 735
Query: 2769 IPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPG-RVCEVKAEARN 2827
+P+ C C + G + T S C CS+ + + C P +C E +
Sbjct: 736 VPIFHCRCHYRGSVYQPGELIPTP--SGLCQCSNGT-VKCDELATPSAVHICPEGKEYFD 792
Query: 2828 C 2828
C
Sbjct: 793 C 793
Score = 201 bits (512), Expect = 7e-51
Identities = 195/769 (25%), Positives = 303/769 (39%), Gaps = 120/769 (15%)
Query: 455 CQVVGGKAGCVAESTAV-CRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSV 513
C VGG C + V C GD H+TTFDGR Y +G C Y +V+ +D
Sbjct: 406 CVCVGGVWNCTEQDCPVQCSVVGDSHFTTFDGRHYSFIGMCQYILVKGTGKDKFTITLQK 465
Query: 514 EAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVD-NQRSRLPVSLSEGRLRVYQ 572
++ G + + L+ ++ V+L RG G +L NQ L + L
Sbjct: 466 APCEQNLGLVCLQSITLILEDDFNKQVTLGRG--GQILTSPNQGFNLNGIVEIQTL---- 519
Query: 573 SGPRAVVELVFGLVVTYDWDCQ-LALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAP 631
S +++ FGL + + D + + + L + ++ + GLCG +NG+ DDFL+P G +
Sbjct: 520 SSLFILLKTTFGLKILFAIDGERIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEG 579
Query: 632 DAVEFASSWKLDDGDYL-----CEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAV 686
A++W++ + D C N G A H C ++ + FA
Sbjct: 580 TPQLHANAWRVSSTCFAPVHVPVVDPCNINQQNI--GYAAH------CDVIHQ--ELFAP 629
Query: 687 CHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPAN-CPLSC 745
CH + P + + C +D C G LC L+ YA C + G+ + D+R+ + C + C
Sbjct: 630 CHIYISPGLYYQLCRHDACKCGSS--CLCNALAHYAYLCGQHGVPI-DFRTQISFCAVVC 686
Query: 746 PANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPG--FVASGGACVPASSCGCTF 803
Y C C SC ++P CS C EGC C G + + CVP C C +
Sbjct: 687 QKGMLYHHCSSFCLHSCISLSSPEQCSD-DCAEGCNCPEGKFYEDTLNFCVPIFHCRCHY 745
Query: 804 QGLQLAPGQ--------------EVWADELCQRRC------------------------- 824
+G PG+ V DEL
Sbjct: 746 RGSVYQPGELIPTPSGLCQCSNGTVKCDELATPSAVHICPEGKEYFDCRFPDPELPAGGV 805
Query: 825 ----TCNGATHQVTCRDKQSCPAGERCS---VQNGLLGC--YPDRFGTCQGSGDPHYVSF 875
TC TC C +G C+ + G+ C YP C GD HY SF
Sbjct: 806 NCETTCANLAMNFTCTPSSPCISGCVCAPGVCRRGMFNCTYYPCP-AVCTIYGDRHYYSF 864
Query: 876 DGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVR 935
DG +D++ C L+ S + V+ +N+ + +++V + ++ +
Sbjct: 865 DGLEYDYISDCQVFLIKSADDSD----ISVIAQNKKCFDNDIVCSKSVLISVGDTEIYLN 920
Query: 936 REYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVR-TDFGLTVTYDWNARVTAKVPSS 994
Q Q F Q+++ G VV + +T+ +D + KV
Sbjct: 921 DTPYKQK------QSGFFLENKSTYQLWKAGYYIVVYFPEKDITILWDRKTTIHIKVGPQ 974
Query: 995 YAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSL 1054
+ L GLCGNF+ ++D+ + NA FG+SW G C D
Sbjct: 975 WKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSW-----------ALGQCESPDET 1023
Query: 1055 V----AQQLQ---SKNECGILADPKGPFRECHSKLDPQGAVRDCVYD--RCLLPGQSGPL 1105
+ A Q + +K EC IL F C + +D ++C D C L G L
Sbjct: 1024 IKPCEAHQNKFPYAKKECSILY--SDIFASCRNVIDVTSFAKNCHEDTCNCNLGGDCECL 1081
Query: 1106 CDALATYAAACQAAGATVHPWRSEELCPLSCPPHSH------YEACSYG 1148
C ++A YA C G ++H WRS +C L C ++ Y SYG
Sbjct: 1082 CTSIAAYAYKCCQEGISIH-WRSSTVCSLDCEYYNEGLGEGPYMLASYG 1129
Score = 85.5 bits (210), Expect = 7e-16
Identities = 97/406 (23%), Positives = 143/406 (35%), Gaps = 47/406 (11%)
Query: 464 CVAESTAVCRAQ--GDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRG 521
C E CR + TFDG + SY +V + E + A +
Sbjct: 1431 CCPEWECPCRCSMLSELSIITFDGNNAALYSMASYILVRIPGE--IIVAHIEKCSMNQAP 1488
Query: 522 SRRVSYVGL--VTVRAYSHSVSLTR----GEVGFVLVDNQRSRLPVSLSEGRLRVYQSGP 575
S R+S + + V H + + R EV ++V P+ S L + SG
Sbjct: 1489 SGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVV-------PLPFSSQELSIEDSGS 1541
Query: 576 RAVVELVFGLVVTYDW---DCQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAPD 632
V+ GL++ + + GLCG N DP DD +G + +
Sbjct: 1542 MYVITTPAGLIIKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTIITN 1601
Query: 633 AVE---FASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHD 689
+ F SW+++ + NC Q R+ F CHD
Sbjct: 1602 MEDIGLFIESWEIEKSFEVTMRRPVRNCTEHDCSQCIDLLNRRI----------FIPCHD 1651
Query: 690 TLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSCPANS 749
+ P F E+ + C LSAY C + I + WR+P C LSCP
Sbjct: 1652 KVSPEDFCEKMWINYTYFWNYE---CDALSAYVALCNKFDICI-QWRTPDYCSLSCPEGK 1707
Query: 750 RYELCGPACPT-SCNGAAAPSNCSGRPCVEGCVCLPGFV---ASGGACVPASSCGCTFQG 805
Y+ C C +C + S E CVC G + C+P C CT
Sbjct: 1708 EYQPCVRPCEARTCLNQWFYGHTSCLNLREDCVCKVGTILHRPHSAQCIPEKECACTDSE 1767
Query: 806 LQLAPGQEVW---ADELCQRRCTCNGATHQV--TCRDKQSCPAGER 846
Q E+W DE +C NG+ + C D++ P ER
Sbjct: 1768 DQPRTAGEIWNGGIDECTLYKCLENGSIIPIEPDC-DEEPTPVCER 1812
Score = 79.0 bits (193), Expect = 7e-14
Identities = 100/440 (22%), Positives = 165/440 (37%), Gaps = 73/440 (16%)
Query: 2418 ECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGS 2477
+CG G C P EC RC + IT DG L+
Sbjct: 1416 DCGFRGRPVQVNSDICCPEWECPC-------------RCSMLSELSIITFDGNNAALYSM 1462
Query: 2478 CSYVLAQVCHPKPGDEDFSIV----LEKNAAGDLQRL------LVTVAGQVVSLAQGQQV 2527
SY+L ++ PG+ + + + + +G + L + T +++ ++V
Sbjct: 1463 ASYILVRI----PGEIIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLARKV 1518
Query: 2528 TVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHL--LMSIPSPFRGRLC-- 2583
VD V LP + + + G V+ T GL + + +HL ++ I FR L
Sbjct: 1519 EVDSIVVPLPFSSQELSIEDSGSMYVITTPAGLIIKW---SHLTGIIDIHFGFRFNLSSY 1575
Query: 2584 --GLCGNFNGNWSDDFVLPNGSAASSVETFGA---AWRAPGS----SKGCGEGCGPQGCP 2634
GLCG N + DD + NG+ +++E G +W S + C C
Sbjct: 1576 TEGLCGICNEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTMRRPVRNCTEHDCS 1635
Query: 2635 VCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSL 2694
C+ L N + F C +SP ++ + + + C +L
Sbjct: 1636 QCI--------------DLLNRR-IFIPCHDKVSPEDFCEKMWINYTYFWN---YECDAL 1677
Query: 2695 AAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTT--RCF 2752
+AY A C + ++ WRT +C L CP Y C R C+ G T+
Sbjct: 1678 SAYVALCNKFDICIQ-WRTPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSCLNLR 1736
Query: 2753 EGCECDDRFLLSQ---GVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCS---CSSSSGL 2806
E C C +L + CIP ++C CT + P + + + + C+ C + +
Sbjct: 1737 EDCVCKVGTILHRPHSAQCIPEKECACT-DSEDQPRTAGEIWNGGIDECTLYKCLENGSI 1795
Query: 2807 TCQAAGC--PPGRVCEVKAE 2824
C P VCE +AE
Sbjct: 1796 IPIEPDCDEEPTPVCEREAE 1815
Score = 78.6 bits (192), Expect = 9e-14
Identities = 95/400 (23%), Positives = 146/400 (36%), Gaps = 56/400 (14%)
Query: 864 CQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAV 923
C + ++FDG +Y+LV G+ + + G + + +
Sbjct: 1441 CSMLSELSIITFDGNNAALYSMASYILVRIPGEIIVAHIEKCSMNQAPSGRISGLCFKKL 1500
Query: 924 RVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDW 983
V K+ V R +V VD ++ LPF + + ++ G V+ T GL + +
Sbjct: 1501 NVTTPIHKIIVNR-LARKVEVDSIVVPLPFSSQELSIE--DSGSMYVITTPAGLIIKW-- 1555
Query: 984 NARVTAKVP---------SSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFG---NS 1031
+ +T + SSY E LCG+C N DP DDL ++ G N G S
Sbjct: 1556 -SHLTGIIDIHFGFRFNLSSYTEGLCGIC---NEDPDDDLRMQNGTIITNMEDIGLFIES 1611
Query: 1032 WQEET-------RPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDP 1084
W+ E RP TE DC + L+ +++ F CH K+ P
Sbjct: 1612 WEIEKSFEVTMRRPVRNCTEH-DCSQCIDLLNRRI---------------FIPCHDKVSP 1655
Query: 1085 QGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEA 1144
+ + CDAL+ Y A C + WR+ + C LSCP Y+
Sbjct: 1656 EDFCEKMWINYTYFWNYE---CDALSAYVALCNKFDICIQ-WRTPDYCSLSCPEGKEYQP 1711
Query: 1145 CSYGCPL-SCGDLPVPGGCGS-ECHEGCVCDEGFAL---SGESCLPLASCGCV-HQGTYH 1198
C C +C + G E CVC G L C+P C C +
Sbjct: 1712 CVRPCEARTCLNQWFYGHTSCLNLREDCVCKVGTILHRPHSAQCIPEKECACTDSEDQPR 1771
Query: 1199 PPGQTFYPGPGCDSLCHCQEGGLVSCESSSCG--PHEACQ 1236
G+ + G +L C E G + C P C+
Sbjct: 1772 TAGEIWNGGIDECTLYKCLENGSIIPIEPDCDEEPTPVCE 1811
Score = 77.8 bits (190), Expect = 2e-13
Identities = 87/345 (25%), Positives = 130/345 (37%), Gaps = 46/345 (13%)
Query: 2074 CQAWGDPHYVTLDGHRFDFQGTCEYLL-SAPCHGPPLGAENFTVTVANEHRGSQAVSYTR 2132
C + +T DG+ Y+L P E ++ A R S
Sbjct: 1441 CSMLSELSIITFDGNNAALYSMASYILVRIPGEIIVAHIEKCSMNQAPSGRISGLCFKKL 1500
Query: 2133 SVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFD 2192
+VT I H + ++ R RK++VD + V LPF L SG+ V+TT +GL + +
Sbjct: 1501 NVTTPI--HKIIVN-RLARKVEVDSIVVPLPFSSQEL-SIEDSGSMYVITTPAGLIIKWS 1556
Query: 2193 G-----DSFVRLRVP-AAYAASLCGLCGNYNQDPADDLKAVGGKPA-----------GWQ 2235
D R ++Y LCG+C N+DP DDL+ G W+
Sbjct: 1557 HLTGIIDIHFGFRFNLSSYTEGLCGIC---NEDPDDDLRMQNGTIITNMEDIGLFIESWE 1613
Query: 2236 VGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPL-APCHGLVPPAQYFQGC 2294
+ + E + CT D I + + PCH V P + +
Sbjct: 1614 I---EKSFEVTMRRPVRNCTEH--------DCSQCIDLLNRRIFIPCHDKVSPEDFCEKM 1662
Query: 2295 LLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPV 2354
++ + C A++ YVA C + +WR PD+C L CP Y+ C C
Sbjct: 1663 WINYTYFWNYE---CDALSAYVALCNKFDICI-QWRTPDYCSLSCPEGKEYQPCVRPCEA 1718
Query: 2355 SCPSLSAPEGCESA--CREGCVCDAGFVL---SGDTCVPVGQCGC 2394
G S RE CVC G +L C+P +C C
Sbjct: 1719 RTCLNQWFYGHTSCLNLREDCVCKVGTILHRPHSAQCIPEKECAC 1763
Score = 65.5 bits (158), Expect = 8e-10
Identities = 89/390 (22%), Positives = 144/390 (36%), Gaps = 54/390 (13%)
Query: 1659 QGGQGVCLPNYEATCW--LWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFT 1716
Q +C P +E C + + +FDG +Y+L PG
Sbjct: 1425 QVNSDICCPEWECPCRCSMLSELSIITFDGNNAALYSMASYILVRI--PG-------EII 1475
Query: 1717 VTTKNQNRGNPAVS-YVRVVTVAALGTNISIHKDEIGKV--RVCVNGVLTALPVSVADGR 1773
V + N A S + + L IHK + ++ +V V+ ++ LP S +
Sbjct: 1476 VAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQE-- 1533
Query: 1774 ISVAQGASKALLVADFGLQVSYD---------WNWRVDVTLPSSYHGAVCGLCGNMDRNP 1824
+S+ S ++ GL + + + +R ++ SSY +CG+C + +P
Sbjct: 1534 LSIEDSGSMYVITTPAGLIIKWSHLTGIIDIHFGFRFNL---SSYTEGLCGIC---NEDP 1587
Query: 1825 NNDQVFPNGTLAPS---IPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCG 1881
++D NGT+ + I ++ SW + R C E Q C
Sbjct: 1588 DDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTM---RRPVRNCTEHDCSQ------CI 1638
Query: 1882 PLASGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIED 1941
L + F CH V PE F + ++ C AL++YVA C + I+
Sbjct: 1639 DLLNRR--IFIPCHDKVSPEDFCEKMWINYTYFWNYE---CDALSAYVALCNKFDICIQ- 1692
Query: 1942 WRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVL---S 1998
WR C ++CPE Y+ C PC A C E C C G +L
Sbjct: 1693 WRTPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSCLN-LREDCVCKVGTILHRPH 1751
Query: 1999 ADRCVPLNNGCGCWANGTYHEAGSEFWADG 2028
+ +C+P C C + E W G
Sbjct: 1752 SAQCIP-EKECACTDSEDQPRTAGEIWNGG 1780
Score = 59.3 bits (142), Expect = 6e-08
Identities = 112/530 (21%), Positives = 177/530 (33%), Gaps = 113/530 (21%)
Query: 1126 WRSEELCPLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGF--ALSGESC 1183
WR E C C ++ CS L+C LP GC C + + DE + C
Sbjct: 1279 WRYEP-CATPC-----FKTCSDPEALACKFLPPVEGCLPYCPKNMILDEVTLKCVYPRDC 1332
Query: 1184 LPLASCGCVHQGTYHPPGQTFYP-----------------------GPGC-----DSLCH 1215
+P+ + T PP + P G C D +
Sbjct: 1333 IPVIPT----EPTLMPPAKPTVPMFTVWEMITPSDITVFDMLTPTTGLECEPQKFDPVYD 1388
Query: 1216 CQEGGLVSCE------SSSCGPHEACQPSGGSLG---------CVAVGSSTCQAS--GDP 1258
C + ++ E S +C P + P G G C C+ S +
Sbjct: 1389 CSQYICLNMEWQLYNWSLNC-PKDVEMPDCGFRGRPVQVNSDICCPEWECPCRCSMLSEL 1447
Query: 1259 HYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANF 1318
TFDG Y+L + G H G + + V
Sbjct: 1448 SIITFDGNNAALYSMASYILVRIPGEIIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIH 1507
Query: 1319 TLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAY-------DLV 1371
+ + + KV V+ + + LP ++ ++ GS VI T GL + + D+
Sbjct: 1508 KIIVNRLARKVEVDSIVVPLP--FSSQELSIEDSGSMYVITTPAGLIIKWSHLTGIIDIH 1565
Query: 1372 YYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFG---NSWE-----EVV 1423
+ R + +Y + +CG+C N DP DD + NG+ N + G SWE EV
Sbjct: 1566 FGFRFNL-SSYTEGLCGIC---NEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVT 1621
Query: 1424 PDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGP 1483
P T DC +C L ++ CH V P+
Sbjct: 1622 MRRPVRNCT-----EHDC---SQCIDLLNRRI---------------FIPCHDKVSPEDF 1658
Query: 1484 LKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCAD 1543
+ + + C + AYV+ C ++ WRT +C + CP Y+ C
Sbjct: 1659 CEKMWINYTYFW---NYECDALSAYVALCNKFDICIQ-WRTPDYCSLSCPEGKEYQPCVR 1714
Query: 1544 TCSLGCSALSAPPQCQDGC---AEGCQCDSGFLY---NGQACVPIQQCGC 1587
C + L+ C E C C G + + C+P ++C C
Sbjct: 1715 PCE-ARTCLNQWFYGHTSCLNLREDCVCKVGTILHRPHSAQCIPEKECAC 1763
Score = 47.0 bits (110), Expect = 3e-04
Identities = 50/204 (24%), Positives = 83/204 (40%), Gaps = 22/204 (10%)
Query: 2793 DCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGA 2852
+C CS + CQ G C++ N G+C + TFDG
Sbjct: 25 ECLNGAFCSKTGTCDCQIFQAL-GTRCQIIPNMGN--GRDGICKTWGQYHFETFDGIYYY 81
Query: 2853 TTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVGQVH-------IFFQDGMVTL 2905
Y + C L+ P Y V H + +G V+ +FF +
Sbjct: 82 FPGNCSYIFAKDCGDLE---PRYTVWV-----HNSPKCLGSVYSCYRSISLFFSNQEEIR 133
Query: 2906 TPNKGVWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQV-WLGANGKVAVIVSNDH 2964
+ NG+ + LP + + + + + D +LV+ G + W G +G + + +S DH
Sbjct: 134 IYGHEIKKNGISLTLP-QTIGQIFIEKLAD-YILVKTTFGFSLAWDGISG-IYLKLSEDH 190
Query: 2965 AGKLCGACGNFDGDQTNDWHDSQE 2988
GK CG CGN++ Q++D+ QE
Sbjct: 191 KGKSCGLCGNYNDIQSDDFIILQE 214
>gi|239744688 PREDICTED: hypothetical protein LOC283310 [Homo sapiens]
Length = 2250
Score = 319 bits (818), Expect = 2e-86
Identities = 290/1160 (25%), Positives = 472/1160 (40%), Gaps = 170/1160 (14%)
Query: 450 AAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLP 509
A G RCQ++ +C+ G H+ TFDG Y G CSY + C D P
Sbjct: 45 ALGTRCQIIPNMGN---GRDGICKTWGQYHFETFDGIYYYFPGNCSYIFAKDCG--DLEP 99
Query: 510 AFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSL---TRGEVGFVLVDNQRSRLPVSLSE- 565
++V N + L +V + S+SL + E+ + +++ + ++L +
Sbjct: 100 RYTVWVHNSPKC--------LGSVYSCYRSISLFFSNQEEIRIYGHEIKKNGISLTLPQT 151
Query: 566 -GRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLT 624
G++ + + +V+ FG + +D + L L + + CGLCGNYN +DDF+
Sbjct: 152 IGQIFIEKLADYILVKTTFGFSLAWDGISGIYLKLSEDHKGKSCGLCGNYNDIQSDDFII 211
Query: 625 PDGALAPDAVEFASSWKLDDGD----YLCEDGCQNNCPACTPG-QAQHYEGDRLCGMLTK 679
D FA+SW + D L N C + P +A ++ C +L
Sbjct: 212 LQEDYTEDIAMFANSWSVQTPDDTKCVLTPSDFPNPCSSGMPAFEAIFFK----CQIL-- 265
Query: 680 LDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRS-- 737
L PF CH+ +DP ++ CV DLC + + CR + YA+AC G + DWR
Sbjct: 266 LQFPFLSCHEYIDPYLYIASCVNDLCKTDDDE-TYCRAATEYARACSHAGYPIQDWRDDF 324
Query: 738 PANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGR--PCVEGCVCLPGFVASGGACVP 795
PA C C + + C CP +C C G C++GC C G V G C+
Sbjct: 325 PA-CTDKCDDSFVHRDCISCCPPTC---TFEKQCLGSNLHCLDGCYCPDGLVMDNGTCIS 380
Query: 796 ASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLG 855
+C C F GL + G ++ ++ C C C G T +Q CP +CSV
Sbjct: 381 LENCPCGFHGLAYSVGSKI--EQEC-TECVCVGGVWNCT---EQDCPV--QCSV------ 426
Query: 856 CYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQ 915
GD H+ +FDGR + F+G C Y+LV G++ + ++ G
Sbjct: 427 -----------VGDSHFTTFDGRHYSFIGMCQYILVKGTGKDKFTITLQKAPCEQNLGLV 475
Query: 916 TVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQA--ADGQVQV-FRQGRDAVVR 972
+ + + +V + R GQ+L P Q +G V++ +++
Sbjct: 476 CLQSITLILEDDFNKQVTLGR--GGQILTS------PNQGFNLNGIVEIQTLSSLFILLK 527
Query: 973 TDFGLTVTYDWNA-RVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNS 1031
T FGL + + + R+ ++ S++ GLCG FNG+ DD G N+
Sbjct: 528 TTFGLKILFAIDGERIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEGTPQLHANA 587
Query: 1032 WQEETRPGCGATEPGDCPKLD--SLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVR 1089
W+ + C A P P +D ++ Q + C ++ F CH + P +
Sbjct: 588 WRVSST--CFA--PVHVPVVDPCNINQQNIGYAAHCDVIHQEL--FAPCHIYISPGLYYQ 641
Query: 1090 DCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGC 1149
C +D C S LC+ALA YA C G + C + C Y CS C
Sbjct: 642 LCRHDACKC--GSSCLCNALAHYAYLCGQHGVPIDFRTQISFCAVVCQKGMLYHHCSSFC 699
Query: 1150 PLSCGDLPVPGGCGSECHEGCVCDEG--FALSGESCLPLASCGCVHQGTYHPPGQTFYPG 1207
SC L P C +C EGC C EG + + C+P+ C C ++G+ + PG+
Sbjct: 700 LHSCISLSSPEQCSDDCAEGCNCPEGKFYEDTLNFCVPIFHCRCHYRGSVYQPGELI--- 756
Query: 1208 PGCDSLCHCQEG----------------------------------GLVSCES--SSCGP 1231
P LC C G G V+CE+ ++
Sbjct: 757 PTPSGLCQCSNGTVKCDELATPSAVHICPEGKEYFDCRFPDPELPAGGVNCETTCANLAM 816
Query: 1232 HEACQPSGGSL-GCVAVGS---------------STCQASGDPHYTTFDGRRFDFMGTCV 1275
+ C PS + GCV + C GD HY +FDG +D++ C
Sbjct: 817 NFTCTPSSPCISGCVCAPGVCRRGMFNCTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQ 876
Query: 1276 YVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVD 1335
L ++ +V+ +N + + ++ + + V + + L +K +G
Sbjct: 877 VFLIKSADDSD----ISVIAQNKKCFDNDIVCSKSVLISVGDTEIYLNDTPYKQKQSGFF 932
Query: 1336 MKLPVVLANGQIRASQHGSDVVIE-TDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYN 1394
++ + + G +V+ + + + +D + + V + ++ GLCGN++
Sbjct: 933 LE-----NKSTYQLWKAGYYIVVYFPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFD 987
Query: 1395 GDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKK 1454
+D N + NA FG+SW +SP PC +K P
Sbjct: 988 KCTSNDMTTSNNLEVRNARVFGDSWALGQCESPDETIKPCE------AHQNKFP------ 1035
Query: 1455 YQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLG--GGNLSILCSNIHAYVSAC 1512
Y K+E C +L S +SC ++D K+C D C GG+ LC++I AY C
Sbjct: 1036 YAKKE-CSILYSDI--FASCRNVIDVTSFAKNCHEDTCNCNLGGDCECLCTSIAAYAYKC 1092
Query: 1513 QAAGGHVEPWRTETFCPMEC 1532
G + WR+ T C ++C
Sbjct: 1093 CQEGISIH-WRSSTVCSLDC 1111
Score = 305 bits (782), Expect = 3e-82
Identities = 307/1192 (25%), Positives = 459/1192 (38%), Gaps = 224/1192 (18%)
Query: 1646 HGVTCRPQETCKEQ-----GGQGVCLPNY----EATCWLWGDPHYHSFDGRKFDFQGTCN 1696
+G C TC Q G + +PN + C WG H+ +FDG + F G C+
Sbjct: 28 NGAFCSKTGTCDCQIFQALGTRCQIIPNMGNGRDGICKTWGQYHFETFDGIYYYFPGNCS 87
Query: 1697 YVLATTGCPGVSTQGLTPFTVTTKNQNR--GNPAVSYVRVVTVAALGTNISIHKDEIGKV 1754
Y+ A C + + +TV N + G+ Y + + I I+ EI K
Sbjct: 88 YIFAKD-CGDLEPR----YTVWVHNSPKCLGSVYSCYRSISLFFSNQEEIRIYGHEIKK- 141
Query: 1755 RVCVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVC 1814
NG+ LP ++ G+I + + A L+ FG +++D + + L + G C
Sbjct: 142 ----NGISLTLPQTI--GQIFIEKLADYILVKTTFGFSLAWDGISGIYLKLSEDHKGKSC 195
Query: 1815 GLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQY 1874
GLCGN + ++D + I ++ SW D C P D
Sbjct: 196 GLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDT-------KCVLTPSD----- 243
Query: 1875 EGPGFCGPLASGTGG--------------PFTTCHAHVPPESFFKGCVLDVCMGGGDRDI 1920
F P +SG PF +CH ++ P + CV D+C D +
Sbjct: 244 ----FPNPCSSGMPAFEAIFFKCQILLQFPFLSCHEYIDPYLYIASCVNDLCKTDDD-ET 298
Query: 1921 LCKALASYVAACQAAGVVIEDWRAQV-GCEITCPENSHYEVCGPPCPASCPSPAPLTTPA 1979
C+A Y AC AG I+DWR C C ++ + C CP +C T
Sbjct: 299 YCRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTC------TFEK 352
Query: 1980 VCEGP---CVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRC 2036
C G C++GC C G V+ C+ L N C C +G + GS+ + C++ C C
Sbjct: 353 QCLGSNLHCLDGCYCPDGLVMDNGTCISLEN-CPCGFHGLAYSVGSKI--EQECTE-CVC 408
Query: 2037 GPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTC 2096
GG CT C PV +C GD H+ T DG + F G C
Sbjct: 409 V--GGVWNCTEQDC-----------------PV---QCSVVGDSHFTTFDGRHYSFIGMC 446
Query: 2097 EYLLSAPCHGPPLGAENFTVTVANEH-RGSQAVSYTRSVTLQI---YNHSLTLSARWPRK 2152
+Y+L G + FT+T+ + + +S+TL + +N +TL
Sbjct: 447 QYILVKGT-----GKDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGR----- 496
Query: 2153 LQVDGVFVALP---FQLDSLLHAH-LSGADVVVTTTSGLSLAF--DGDSFVRLRVPAAYA 2206
G + P F L+ ++ LS +++ TT GL + F DG+ + +++ +A+
Sbjct: 497 ---GGQILTSPNQGFNLNGIVEIQTLSSLFILLKTTFGLKILFAIDGER-IYIQLTSAWK 552
Query: 2207 ASLCGLCGNYNQDPADDLKAVGGKPAG--------WQVGGAQGCGECVSKPCPSPCTPEQ 2258
GLCG +N + DD + G G W+V C V P PC Q
Sbjct: 553 RRTLGLCGTFNGNIRDDFLSPSGMIEGTPQLHANAWRVSST--CFAPVHVPVVDPCNINQ 610
Query: 2259 QESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAA 2318
Q + G C VI APCH + P Y+Q C DAC+ LC A+A Y
Sbjct: 611 Q-NIGYAAHCDVIHQE--LFAPCHIYISPGLYYQLCRHDACKCGS--SCLCNALAHYAYL 665
Query: 2319 CQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAG 2378
C G + + FC + C Y C C SC SLS+PE C C EGC C G
Sbjct: 666 CGQHGVPIDFRTQISFCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEG 725
Query: 2379 --FVLSGDTCVPVGQCGCLHDGRYYPLGEVF----------------------------- 2407
+ + + CVP+ C C + G Y GE+
Sbjct: 726 KFYEDTLNFCVPIFHCRCHYRGSVYQPGELIPTPSGLCQCSNGTVKCDELATPSAVHICP 785
Query: 2408 ---------YPGPE-------CERRC-------ECGPGGHVTCQEGAACGPHEECRLEDG 2444
+P PE CE C C P C G C P CR G
Sbjct: 786 EGKEYFDCRFPDPELPAGGVNCETTCANLAMNFTCTPSS--PCISGCVCAP-GVCR--RG 840
Query: 2445 VQACHATGC-GRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNA 2503
+ C C C G HY + DG YD C L + D D S++ +
Sbjct: 841 MFNCTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLIK----SADDSDISVIAQNKK 896
Query: 2504 AGDLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRN-----------M 2552
D +V ++S+ + D P + E ++ +
Sbjct: 897 CFDND--IVCSKSVLISVGDTEIYLND-----TPYKQKQSGFFLENKSTYQLWKAGYYIV 949
Query: 2553 VLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFG 2612
V K + +L+D + + + ++ +L GLCGNF+ S+D N + FG
Sbjct: 950 VYFPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFG 1009
Query: 2613 AAWRAPGSSKGCGEGCGPQGCPVCLAEETA-PYESNEACGQLRNPQGPFATCQAVLSPSE 2671
+W A G + E P C A + PY E C L + FA+C+ V+ +
Sbjct: 1010 DSW-ALGQCESPDETIKP-----CEAHQNKFPYAKKE-CSILYS--DIFASCRNVIDVTS 1060
Query: 2672 YFRQCVYDLCAQK--GDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHC 2721
+ + C D C GD LC S+AAY C G+++ WR+ + C L C
Sbjct: 1061 FAKNCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIH-WRSSTVCSLDC 1111
Score = 302 bits (774), Expect = 3e-81
Identities = 292/1190 (24%), Positives = 462/1190 (38%), Gaps = 157/1190 (13%)
Query: 820 CQRRCTCNGA--THQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDG 877
C C NGA + TC + G RC + + R G C+ G H+ +FDG
Sbjct: 22 CPYECL-NGAFCSKTGTCDCQIFQALGTRCQIIPNMGN---GRDGICKTWGQYHFETFDG 77
Query: 878 RRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHR--GSQTVSYTRAVRVEARGVKVAVR 935
+ F G C+Y+ CG P + V V N + GS Y + ++ +
Sbjct: 78 IYYYFPGNCSYIFAKDCGDLE--PRYTVWVHNSPKCLGSVYSCYRSISLFFSNQEEIRI- 134
Query: 936 REYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSY 995
Y ++ + + LP GQ+ + + +V+T FG ++ +D + + K+ +
Sbjct: 135 --YGHEIKKNGISLTLP--QTIGQIFIEKLADYILVKTTFGFSLAWDGISGIYLKLSEDH 190
Query: 996 AEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPG--CGATEPGDCPKLDS 1053
CGLCGN+N +DD + + F NSW +T C T P D P S
Sbjct: 191 KGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVLT-PSDFPNPCS 249
Query: 1054 LVAQQLQS-KNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATY 1112
++ +C IL + PF CH +DP + CV D C C A Y
Sbjct: 250 SGMPAFEAIFFKCQILL--QFPFLSCHEYIDPYLYIASCVNDLCKTDDDE-TYCRAATEY 306
Query: 1113 AAACQAAGATVHPWRSE-ELCPLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCV 1171
A AC AG + WR + C C + C CP +C G C +GC
Sbjct: 307 ARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTCTFEKQCLGSNLHCLDGCY 366
Query: 1172 CDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGP 1231
C +G + +C+ L +C C G + G C C C GG+ +C C
Sbjct: 367 CPDGLVMDNGTCISLENCPCGFHGLAYSVGSKI--EQECTE-CVC-VGGVWNCTEQDC-- 420
Query: 1232 HEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRF 1291
C GD H+TTFDGR + F+G C Y+L + GT G +F
Sbjct: 421 -----------------PVQCSVVGDSHFTTFDGRHYSFIGMCQYILVK--GT--GKDKF 459
Query: 1292 AV-LQENVAWGN-GRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRA 1349
+ LQ+ N G V + + + +F ++ + + + + NG +
Sbjct: 460 TITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGRGGQILTSPNQGFNL---NGIVEI 516
Query: 1350 SQHGS-DVVIETDFGLRVAYDL---VYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPN 1405
S ++++T FGL++ + + Y+++T + ++ GLCG +NG+ +DDF P+
Sbjct: 517 QTLSSLFILLKTTFGLKILFAIDGERIYIQLT--SAWKRRTLGLCGTFNGNIRDDFLSPS 574
Query: 1406 GSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLS 1465
G G N+W S C P P I ++ C ++
Sbjct: 575 GMIEGTPQLHANAWR---VSSTCFAPVHVPVVDPCNIN--------QQNIGYAAHCDVIH 623
Query: 1466 SPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTE 1525
+ CH + P + C D C G S LC+ + Y C G ++ +RT+
Sbjct: 624 QEL--FAPCHIYISPGLYYQLCRHDACKCGS--SCLCNALAHYAYLCGQHGVPID-FRTQ 678
Query: 1526 -TFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNG--QACVPI 1582
+FC + C Y C+ C C +LS+P QC D CAEGC C G Y CVPI
Sbjct: 679 ISFCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEGKFYEDTLNFCVPI 738
Query: 1583 QQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQE-------HSCKPGQV---CQ- 1631
C C++ G Y+P + LI C C G + C E H C G+ C+
Sbjct: 739 FHCRCHYRGSVYQPGE--LIPTPSGLCQCSNGT-VKCDELATPSAVHICPEGKEYFDCRF 795
Query: 1632 -----PSGGI------------LSCVTKDPC-HGVTCRPQETCKEQGGQGVCLPNYEATC 1673
P+GG+ +C PC G C P C+ +G A C
Sbjct: 796 PDPELPAGGVNCETTCANLAMNFTCTPSSPCISGCVCAP-GVCR-RGMFNCTYYPCPAVC 853
Query: 1674 WLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVR 1733
++GD HY+SFDG ++D+ C L + + + +V +N+ + + +
Sbjct: 854 TIYGDRHYYSFDGLEYDYISDCQVFL-------IKSADDSDISVIAQNKKCFDNDIVCSK 906
Query: 1734 VVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVADF---- 1789
V ++ T I L P + ++ L A +
Sbjct: 907 SVLISVGDTEI----------------YLNDTPYKQKQSGFFLENKSTYQLWKAGYYIVV 950
Query: 1790 -----GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGG 1844
+ + +D + + + + + GLCGN D+ +ND N + ++G
Sbjct: 951 YFPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGD 1010
Query: 1845 SWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFF 1904
SW +C T Q + P + F +C + SF
Sbjct: 1011 SW--------ALGQCESPDETIKPCEAHQNKFPYAKKECSILYSDIFASCRNVIDVTSFA 1062
Query: 1905 KGCVLDVCMG--GGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITC 1952
K C D C GGD + LC ++A+Y C G+ I WR+ C + C
Sbjct: 1063 KNCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIH-WRSSTVCSLDC 1111
Score = 254 bits (648), Expect = 1e-66
Identities = 226/841 (26%), Positives = 342/841 (40%), Gaps = 99/841 (11%)
Query: 2024 FWADGTCSQWCRCGPGGGSLVCTPASC------GLGEVCGLLPSGQHGCQPVSTAECQAW 2077
F G+C C G+ +C LG C ++P+ +G + C+ W
Sbjct: 16 FSPSGSCPYECL----NGAFCSKTGTCDCQIFQALGTRCQIIPNMGNGRDGI----CKTW 67
Query: 2078 GDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAV-SYTRSVTL 2136
G H+ T DG + F G C Y+ + C +TV V N + +V S RS++L
Sbjct: 68 GQYHFETFDGIYYYFPGNCSYIFAKDCGDLE---PRYTVWVHNSPKCLGSVYSCYRSISL 124
Query: 2137 QIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSF 2196
N + +++ +G+ + LP + + L+ ++V TT G SLA+DG S
Sbjct: 125 FFSNQEEIRI--YGHEIKKNGISLTLPQTIGQIFIEKLADY-ILVKTTFGFSLAWDGISG 181
Query: 2197 VRLRVPAAYAASLCGLCGNYNQDPADDL--------KAVGGKPAGWQVGGAQGCGECVSK 2248
+ L++ + CGLCGNYN +DD + + W V +CV
Sbjct: 182 IYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDT-KCVLT 240
Query: 2249 PC--PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPG 2306
P P+PC+ C ++ P CH + P Y C+ D C+
Sbjct: 241 PSDFPNPCSSGMPAFEAIFFKCQIL--LQFPFLSCHEYIDPYLYIASCVNDLCKTDDDET 298
Query: 2307 GLCPAVATYVAACQAAGAQLGEWRRPDF--CPLQCPAHSHYELCGDSCPVSCPSLSAPEG 2364
C A Y AC AG + +WR DF C +C + C CP +C G
Sbjct: 299 -YCRAATEYARACSHAGYPIQDWR-DDFPACTDKCDDSFVHRDCISCCPPTCTFEKQCLG 356
Query: 2365 CESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGH 2424
C +GC C G V+ TC+ + C C G Y +G + E+ C
Sbjct: 357 SNLHCLDGCYCPDGLVMDNGTCISLENCPCGFHGLAYSVGS------KIEQECT------ 404
Query: 2425 VTCQEGAACGPHEECRLEDGVQACHATGCG-RCLANGGIHYITLDGRVYDLHGSCSYVLA 2483
EC GV C C +C G H+ T DGR Y G C Y+L
Sbjct: 405 -------------ECVCVGGVWNCTEQDCPVQCSVVGDSHFTTFDGRHYSFIGMCQYILV 451
Query: 2484 QVCHPKPGDEDFSIVLEKNAAGD------LQRLLVTVA---GQVVSLAQGQQV-TVDGEA 2533
+ G + F+I L+K LQ + + + + V+L +G Q+ T +
Sbjct: 452 K----GTGKDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGRGGQILTSPNQG 507
Query: 2534 VALPVAVGRVRV-TAEGRNMVLQTTKGLRLLF--DGDAHLLMSIPSPFRGRLCGLCGNFN 2590
L G V + T ++L+TT GL++LF DG+ + + + S ++ R GLCG FN
Sbjct: 508 FNLN---GIVEIQTLSSLFILLKTTFGLKILFAIDGE-RIYIQLTSAWKRRTLGLCGTFN 563
Query: 2591 GNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEAC 2650
GN DDF+ P+G + + AWR SS P P + ++ Y ++ C
Sbjct: 564 GNIRDDFLSPSGMIEGTPQLHANAWRV--SSTCFAPVHVPVVDPCNINQQNIGYAAH--C 619
Query: 2651 GQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKP 2710
+ Q FA C +SP Y++ C +D C K + LC +LA Y C GV +
Sbjct: 620 DVIH--QELFAPCHIYISPGLYYQLCRHDAC--KCGSSCLCNALAHYAYLCGQHGVPIDF 675
Query: 2711 WRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQ--GVC 2768
SFC + C Y C+ C SC +LS C+ C EGC C + C
Sbjct: 676 RTQISFCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEGKFYEDTLNFC 735
Query: 2769 IPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPG-RVCEVKAEARN 2827
+P+ C C + G + T S C CS+ + + C P +C E +
Sbjct: 736 VPIFHCRCHYRGSVYQPGELIPTP--SGLCQCSNGT-VKCDELATPSAVHICPEGKEYFD 792
Query: 2828 C 2828
C
Sbjct: 793 C 793
Score = 201 bits (512), Expect = 7e-51
Identities = 195/769 (25%), Positives = 303/769 (39%), Gaps = 120/769 (15%)
Query: 455 CQVVGGKAGCVAESTAV-CRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSV 513
C VGG C + V C GD H+TTFDGR Y +G C Y +V+ +D
Sbjct: 406 CVCVGGVWNCTEQDCPVQCSVVGDSHFTTFDGRHYSFIGMCQYILVKGTGKDKFTITLQK 465
Query: 514 EAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVD-NQRSRLPVSLSEGRLRVYQ 572
++ G + + L+ ++ V+L RG G +L NQ L + L
Sbjct: 466 APCEQNLGLVCLQSITLILEDDFNKQVTLGRG--GQILTSPNQGFNLNGIVEIQTL---- 519
Query: 573 SGPRAVVELVFGLVVTYDWDCQ-LALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAP 631
S +++ FGL + + D + + + L + ++ + GLCG +NG+ DDFL+P G +
Sbjct: 520 SSLFILLKTTFGLKILFAIDGERIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEG 579
Query: 632 DAVEFASSWKLDDGDYL-----CEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAV 686
A++W++ + D C N G A H C ++ + FA
Sbjct: 580 TPQLHANAWRVSSTCFAPVHVPVVDPCNINQQNI--GYAAH------CDVIHQ--ELFAP 629
Query: 687 CHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPAN-CPLSC 745
CH + P + + C +D C G LC L+ YA C + G+ + D+R+ + C + C
Sbjct: 630 CHIYISPGLYYQLCRHDACKCGSS--CLCNALAHYAYLCGQHGVPI-DFRTQISFCAVVC 686
Query: 746 PANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPG--FVASGGACVPASSCGCTF 803
Y C C SC ++P CS C EGC C G + + CVP C C +
Sbjct: 687 QKGMLYHHCSSFCLHSCISLSSPEQCSD-DCAEGCNCPEGKFYEDTLNFCVPIFHCRCHY 745
Query: 804 QGLQLAPGQ--------------EVWADELCQRRC------------------------- 824
+G PG+ V DEL
Sbjct: 746 RGSVYQPGELIPTPSGLCQCSNGTVKCDELATPSAVHICPEGKEYFDCRFPDPELPAGGV 805
Query: 825 ----TCNGATHQVTCRDKQSCPAGERCS---VQNGLLGC--YPDRFGTCQGSGDPHYVSF 875
TC TC C +G C+ + G+ C YP C GD HY SF
Sbjct: 806 NCETTCANLAMNFTCTPSSPCISGCVCAPGVCRRGMFNCTYYPCP-AVCTIYGDRHYYSF 864
Query: 876 DGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVR 935
DG +D++ C L+ S + V+ +N+ + +++V + ++ +
Sbjct: 865 DGLEYDYISDCQVFLIKSADDSD----ISVIAQNKKCFDNDIVCSKSVLISVGDTEIYLN 920
Query: 936 REYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVR-TDFGLTVTYDWNARVTAKVPSS 994
Q Q F Q+++ G VV + +T+ +D + KV
Sbjct: 921 DTPYKQK------QSGFFLENKSTYQLWKAGYYIVVYFPEKDITILWDRKTTIHIKVGPQ 974
Query: 995 YAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSL 1054
+ L GLCGNF+ ++D+ + NA FG+SW G C D
Sbjct: 975 WKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSW-----------ALGQCESPDET 1023
Query: 1055 V----AQQLQ---SKNECGILADPKGPFRECHSKLDPQGAVRDCVYD--RCLLPGQSGPL 1105
+ A Q + +K EC IL F C + +D ++C D C L G L
Sbjct: 1024 IKPCEAHQNKFPYAKKECSILY--SDIFASCRNVIDVTSFAKNCHEDTCNCNLGGDCECL 1081
Query: 1106 CDALATYAAACQAAGATVHPWRSEELCPLSCPPHSH------YEACSYG 1148
C ++A YA C G ++H WRS +C L C ++ Y SYG
Sbjct: 1082 CTSIAAYAYKCCQEGISIH-WRSSTVCSLDCEYYNEGLGEGPYMLASYG 1129
Score = 85.5 bits (210), Expect = 7e-16
Identities = 97/406 (23%), Positives = 143/406 (35%), Gaps = 47/406 (11%)
Query: 464 CVAESTAVCRAQ--GDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRG 521
C E CR + TFDG + SY +V + E + A +
Sbjct: 1431 CCPEWECPCRCSMLSELSIITFDGNNAALYSMASYILVRIPGE--IIVAHIEKCSMNQAP 1488
Query: 522 SRRVSYVGL--VTVRAYSHSVSLTR----GEVGFVLVDNQRSRLPVSLSEGRLRVYQSGP 575
S R+S + + V H + + R EV ++V P+ S L + SG
Sbjct: 1489 SGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVV-------PLPFSSQELSIEDSGS 1541
Query: 576 RAVVELVFGLVVTYDW---DCQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAPD 632
V+ GL++ + + GLCG N DP DD +G + +
Sbjct: 1542 MYVITTPAGLIIKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTIITN 1601
Query: 633 AVE---FASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHD 689
+ F SW+++ + NC Q R+ F CHD
Sbjct: 1602 MEDIGLFIESWEIEKSFEVTMRRPVRNCTEHDCSQCIDLLNRRI----------FIPCHD 1651
Query: 690 TLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSCPANS 749
+ P F E+ + C LSAY C + I + WR+P C LSCP
Sbjct: 1652 KVSPEDFCEKMWINYTYFWNYE---CDALSAYVALCNKFDICI-QWRTPDYCSLSCPEGK 1707
Query: 750 RYELCGPACPT-SCNGAAAPSNCSGRPCVEGCVCLPGFV---ASGGACVPASSCGCTFQG 805
Y+ C C +C + S E CVC G + C+P C CT
Sbjct: 1708 EYQPCVRPCEARTCLNQWFYGHTSCLNLREDCVCKVGTILHRPHSAQCIPEKECACTDSE 1767
Query: 806 LQLAPGQEVW---ADELCQRRCTCNGATHQV--TCRDKQSCPAGER 846
Q E+W DE +C NG+ + C D++ P ER
Sbjct: 1768 DQPRTAGEIWNGGIDECTLYKCLENGSIIPIEPDC-DEEPTPVCER 1812
Score = 79.0 bits (193), Expect = 7e-14
Identities = 100/440 (22%), Positives = 165/440 (37%), Gaps = 73/440 (16%)
Query: 2418 ECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGS 2477
+CG G C P EC RC + IT DG L+
Sbjct: 1416 DCGFRGRPVQVNSDICCPEWECPC-------------RCSMLSELSIITFDGNNAALYSM 1462
Query: 2478 CSYVLAQVCHPKPGDEDFSIV----LEKNAAGDLQRL------LVTVAGQVVSLAQGQQV 2527
SY+L ++ PG+ + + + + +G + L + T +++ ++V
Sbjct: 1463 ASYILVRI----PGEIIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLARKV 1518
Query: 2528 TVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHL--LMSIPSPFRGRLC-- 2583
VD V LP + + + G V+ T GL + + +HL ++ I FR L
Sbjct: 1519 EVDSIVVPLPFSSQELSIEDSGSMYVITTPAGLIIKW---SHLTGIIDIHFGFRFNLSSY 1575
Query: 2584 --GLCGNFNGNWSDDFVLPNGSAASSVETFGA---AWRAPGS----SKGCGEGCGPQGCP 2634
GLCG N + DD + NG+ +++E G +W S + C C
Sbjct: 1576 TEGLCGICNEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTMRRPVRNCTEHDCS 1635
Query: 2635 VCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSL 2694
C+ L N + F C +SP ++ + + + C +L
Sbjct: 1636 QCI--------------DLLNRR-IFIPCHDKVSPEDFCEKMWINYTYFWN---YECDAL 1677
Query: 2695 AAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTT--RCF 2752
+AY A C + ++ WRT +C L CP Y C R C+ G T+
Sbjct: 1678 SAYVALCNKFDICIQ-WRTPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSCLNLR 1736
Query: 2753 EGCECDDRFLLSQ---GVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCS---CSSSSGL 2806
E C C +L + CIP ++C CT + P + + + + C+ C + +
Sbjct: 1737 EDCVCKVGTILHRPHSAQCIPEKECACT-DSEDQPRTAGEIWNGGIDECTLYKCLENGSI 1795
Query: 2807 TCQAAGC--PPGRVCEVKAE 2824
C P VCE +AE
Sbjct: 1796 IPIEPDCDEEPTPVCEREAE 1815
Score = 78.6 bits (192), Expect = 9e-14
Identities = 95/400 (23%), Positives = 146/400 (36%), Gaps = 56/400 (14%)
Query: 864 CQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAV 923
C + ++FDG +Y+LV G+ + + G + + +
Sbjct: 1441 CSMLSELSIITFDGNNAALYSMASYILVRIPGEIIVAHIEKCSMNQAPSGRISGLCFKKL 1500
Query: 924 RVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDW 983
V K+ V R +V VD ++ LPF + + ++ G V+ T GL + +
Sbjct: 1501 NVTTPIHKIIVNR-LARKVEVDSIVVPLPFSSQELSIE--DSGSMYVITTPAGLIIKW-- 1555
Query: 984 NARVTAKVP---------SSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFG---NS 1031
+ +T + SSY E LCG+C N DP DDL ++ G N G S
Sbjct: 1556 -SHLTGIIDIHFGFRFNLSSYTEGLCGIC---NEDPDDDLRMQNGTIITNMEDIGLFIES 1611
Query: 1032 WQEET-------RPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDP 1084
W+ E RP TE DC + L+ +++ F CH K+ P
Sbjct: 1612 WEIEKSFEVTMRRPVRNCTEH-DCSQCIDLLNRRI---------------FIPCHDKVSP 1655
Query: 1085 QGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEA 1144
+ + CDAL+ Y A C + WR+ + C LSCP Y+
Sbjct: 1656 EDFCEKMWINYTYFWNYE---CDALSAYVALCNKFDICIQ-WRTPDYCSLSCPEGKEYQP 1711
Query: 1145 CSYGCPL-SCGDLPVPGGCGS-ECHEGCVCDEGFAL---SGESCLPLASCGCV-HQGTYH 1198
C C +C + G E CVC G L C+P C C +
Sbjct: 1712 CVRPCEARTCLNQWFYGHTSCLNLREDCVCKVGTILHRPHSAQCIPEKECACTDSEDQPR 1771
Query: 1199 PPGQTFYPGPGCDSLCHCQEGGLVSCESSSCG--PHEACQ 1236
G+ + G +L C E G + C P C+
Sbjct: 1772 TAGEIWNGGIDECTLYKCLENGSIIPIEPDCDEEPTPVCE 1811
Score = 77.8 bits (190), Expect = 2e-13
Identities = 87/345 (25%), Positives = 130/345 (37%), Gaps = 46/345 (13%)
Query: 2074 CQAWGDPHYVTLDGHRFDFQGTCEYLL-SAPCHGPPLGAENFTVTVANEHRGSQAVSYTR 2132
C + +T DG+ Y+L P E ++ A R S
Sbjct: 1441 CSMLSELSIITFDGNNAALYSMASYILVRIPGEIIVAHIEKCSMNQAPSGRISGLCFKKL 1500
Query: 2133 SVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFD 2192
+VT I H + ++ R RK++VD + V LPF L SG+ V+TT +GL + +
Sbjct: 1501 NVTTPI--HKIIVN-RLARKVEVDSIVVPLPFSSQEL-SIEDSGSMYVITTPAGLIIKWS 1556
Query: 2193 G-----DSFVRLRVP-AAYAASLCGLCGNYNQDPADDLKAVGGKPA-----------GWQ 2235
D R ++Y LCG+C N+DP DDL+ G W+
Sbjct: 1557 HLTGIIDIHFGFRFNLSSYTEGLCGIC---NEDPDDDLRMQNGTIITNMEDIGLFIESWE 1613
Query: 2236 VGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPL-APCHGLVPPAQYFQGC 2294
+ + E + CT D I + + PCH V P + +
Sbjct: 1614 I---EKSFEVTMRRPVRNCTEH--------DCSQCIDLLNRRIFIPCHDKVSPEDFCEKM 1662
Query: 2295 LLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPV 2354
++ + C A++ YVA C + +WR PD+C L CP Y+ C C
Sbjct: 1663 WINYTYFWNYE---CDALSAYVALCNKFDICI-QWRTPDYCSLSCPEGKEYQPCVRPCEA 1718
Query: 2355 SCPSLSAPEGCESA--CREGCVCDAGFVL---SGDTCVPVGQCGC 2394
G S RE CVC G +L C+P +C C
Sbjct: 1719 RTCLNQWFYGHTSCLNLREDCVCKVGTILHRPHSAQCIPEKECAC 1763
Score = 65.5 bits (158), Expect = 8e-10
Identities = 89/390 (22%), Positives = 144/390 (36%), Gaps = 54/390 (13%)
Query: 1659 QGGQGVCLPNYEATCW--LWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFT 1716
Q +C P +E C + + +FDG +Y+L PG
Sbjct: 1425 QVNSDICCPEWECPCRCSMLSELSIITFDGNNAALYSMASYILVRI--PG-------EII 1475
Query: 1717 VTTKNQNRGNPAVS-YVRVVTVAALGTNISIHKDEIGKV--RVCVNGVLTALPVSVADGR 1773
V + N A S + + L IHK + ++ +V V+ ++ LP S +
Sbjct: 1476 VAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQE-- 1533
Query: 1774 ISVAQGASKALLVADFGLQVSYD---------WNWRVDVTLPSSYHGAVCGLCGNMDRNP 1824
+S+ S ++ GL + + + +R ++ SSY +CG+C + +P
Sbjct: 1534 LSIEDSGSMYVITTPAGLIIKWSHLTGIIDIHFGFRFNL---SSYTEGLCGIC---NEDP 1587
Query: 1825 NNDQVFPNGTLAPS---IPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCG 1881
++D NGT+ + I ++ SW + R C E Q C
Sbjct: 1588 DDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTM---RRPVRNCTEHDCSQ------CI 1638
Query: 1882 PLASGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIED 1941
L + F CH V PE F + ++ C AL++YVA C + I+
Sbjct: 1639 DLLNRR--IFIPCHDKVSPEDFCEKMWINYTYFWNYE---CDALSAYVALCNKFDICIQ- 1692
Query: 1942 WRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVL---S 1998
WR C ++CPE Y+ C PC A C E C C G +L
Sbjct: 1693 WRTPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSCLN-LREDCVCKVGTILHRPH 1751
Query: 1999 ADRCVPLNNGCGCWANGTYHEAGSEFWADG 2028
+ +C+P C C + E W G
Sbjct: 1752 SAQCIP-EKECACTDSEDQPRTAGEIWNGG 1780
Score = 59.3 bits (142), Expect = 6e-08
Identities = 112/530 (21%), Positives = 177/530 (33%), Gaps = 113/530 (21%)
Query: 1126 WRSEELCPLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGF--ALSGESC 1183
WR E C C ++ CS L+C LP GC C + + DE + C
Sbjct: 1279 WRYEP-CATPC-----FKTCSDPEALACKFLPPVEGCLPYCPKNMILDEVTLKCVYPRDC 1332
Query: 1184 LPLASCGCVHQGTYHPPGQTFYP-----------------------GPGC-----DSLCH 1215
+P+ + T PP + P G C D +
Sbjct: 1333 IPVIPT----EPTLMPPAKPTVPMFTVWEMITPSDITVFDMLTPTTGLECEPQKFDPVYD 1388
Query: 1216 CQEGGLVSCE------SSSCGPHEACQPSGGSLG---------CVAVGSSTCQAS--GDP 1258
C + ++ E S +C P + P G G C C+ S +
Sbjct: 1389 CSQYICLNMEWQLYNWSLNC-PKDVEMPDCGFRGRPVQVNSDICCPEWECPCRCSMLSEL 1447
Query: 1259 HYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANF 1318
TFDG Y+L + G H G + + V
Sbjct: 1448 SIITFDGNNAALYSMASYILVRIPGEIIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIH 1507
Query: 1319 TLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAY-------DLV 1371
+ + + KV V+ + + LP ++ ++ GS VI T GL + + D+
Sbjct: 1508 KIIVNRLARKVEVDSIVVPLP--FSSQELSIEDSGSMYVITTPAGLIIKWSHLTGIIDIH 1565
Query: 1372 YYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFG---NSWE-----EVV 1423
+ R + +Y + +CG+C N DP DD + NG+ N + G SWE EV
Sbjct: 1566 FGFRFNL-SSYTEGLCGIC---NEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVT 1621
Query: 1424 PDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGP 1483
P T DC +C L ++ CH V P+
Sbjct: 1622 MRRPVRNCT-----EHDC---SQCIDLLNRRI---------------FIPCHDKVSPEDF 1658
Query: 1484 LKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCAD 1543
+ + + C + AYV+ C ++ WRT +C + CP Y+ C
Sbjct: 1659 CEKMWINYTYFW---NYECDALSAYVALCNKFDICIQ-WRTPDYCSLSCPEGKEYQPCVR 1714
Query: 1544 TCSLGCSALSAPPQCQDGC---AEGCQCDSGFLY---NGQACVPIQQCGC 1587
C + L+ C E C C G + + C+P ++C C
Sbjct: 1715 PCE-ARTCLNQWFYGHTSCLNLREDCVCKVGTILHRPHSAQCIPEKECAC 1763
Score = 47.0 bits (110), Expect = 3e-04
Identities = 50/204 (24%), Positives = 83/204 (40%), Gaps = 22/204 (10%)
Query: 2793 DCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGA 2852
+C CS + CQ G C++ N G+C + TFDG
Sbjct: 25 ECLNGAFCSKTGTCDCQIFQAL-GTRCQIIPNMGN--GRDGICKTWGQYHFETFDGIYYY 81
Query: 2853 TTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVGQVH-------IFFQDGMVTL 2905
Y + C L+ P Y V H + +G V+ +FF +
Sbjct: 82 FPGNCSYIFAKDCGDLE---PRYTVWV-----HNSPKCLGSVYSCYRSISLFFSNQEEIR 133
Query: 2906 TPNKGVWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQV-WLGANGKVAVIVSNDH 2964
+ NG+ + LP + + + + + D +LV+ G + W G +G + + +S DH
Sbjct: 134 IYGHEIKKNGISLTLP-QTIGQIFIEKLAD-YILVKTTFGFSLAWDGISG-IYLKLSEDH 190
Query: 2965 AGKLCGACGNFDGDQTNDWHDSQE 2988
GK CG CGN++ Q++D+ QE
Sbjct: 191 KGKSCGLCGNYNDIQSDDFIILQE 214
>gi|151301154 mucin 6, gastric [Homo sapiens]
Length = 2439
Score = 311 bits (798), Expect = 5e-84
Identities = 330/1245 (26%), Positives = 475/1245 (38%), Gaps = 187/1245 (15%)
Query: 858 PDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTV 917
PD+ G C G H+ +FD +DF GTC Y+ +C A P F V + GS +
Sbjct: 40 PDK-GQCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKD--AFPTFSVQLRRGPDGSIS- 95
Query: 918 SYTRAVRVEARGVKVAVRREYPGQVLVDDV-LQYLPFQAADGQVQVFRQGRDAVVRT-DF 975
+ VE V V + V D+ + LP+ + Q+ F Q V + +
Sbjct: 96 ----RIIVELGASVVTVSEAI---ISVKDIGVISLPYTSNGLQITPFGQSVRLVAKQLEL 148
Query: 976 GLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEE 1035
L V + ++ + V Y +CGLCGNF+G ++ G + F + Q+
Sbjct: 149 ELEVVWGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEG-KFLEPHKFA-ALQKL 206
Query: 1036 TRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDR 1095
PG E + S +Q Q C L P EC +P V C D
Sbjct: 207 DDPG----EICTFQDIPSTHVRQAQHARICTQLLTLVAP--ECSVSKEP--FVLSCQADV 258
Query: 1096 CLLPGQSGPL---CDALATYAAACQAAGATVHPWRSEELCPLS-CPPHSHYEACSYGCPL 1151
P Q GP C L+ Y+ C G V WRS LC + CP + Y+ C C
Sbjct: 259 AAAP-QPGPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSACVK 317
Query: 1152 SCGDLPVPGGCGSECHEGCVCDEGFALS----GESCLPLASCGCVHQGTYHPPGQTFYPG 1207
+C + C S C GC C EG L+ +C+P+ C CV G + PG+
Sbjct: 318 TCSN--PQHSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTIAA 375
Query: 1208 PGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRR 1267
C + C C G V C C H C G TTFD R
Sbjct: 376 --CQT-CRCTLGRWV-CTERPCPGH-------------------CSLEGGSFVTTFDARP 412
Query: 1268 FDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQW 1327
+ F GTC Y+L Q+ AV ++ G + V V ++ + +
Sbjct: 413 YRFHGTCTYILLQSPQLPEDGALMAVYDKS---GVSHSETSLVAVVYLSRQDKIVISQDE 469
Query: 1328 KVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDL--VYYVRVTVPGNYYQQ 1385
VT NG LP N + Q + + + T FGL + L ++ VTV + Q
Sbjct: 470 VVTNNGEAKWLPYKTRNITV-FRQTSTHLQMATSFGLELVVQLRPIFQAYVTVGPQFRGQ 528
Query: 1386 MCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSH 1445
GLCGN+NGD DDF G G A+ F +SW CP E +
Sbjct: 529 TRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWRA----------GNCPAALER--ETD 576
Query: 1446 KCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNI 1505
C K E C +L CH V+P K C++ C +C+ +
Sbjct: 577 PCSMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQACNYEETFPHICAAL 636
Query: 1506 HAYVSACQAAGGHVEPWRTETF-CPMECPPNSHYELCADTCSLGCSALS-APPQCQDGCA 1563
YV AC G + WR+ C + C N+ + + C C +LS +C
Sbjct: 637 GDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLSLSDRATECHHSAV 696
Query: 1564 --EGCQCDSGFLYNGQA-CVPIQQCGCYHNGV-YYEPEQTVLIDNCRQQC---------- 1609
+GC C G N + CV QC C G + EQ+ +I+ C
Sbjct: 697 PVDGCNCPDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVINGITCHCINGRLSCPQR 756
Query: 1610 ------TCHAGK--------------------------GMVCQEHSCKPGQVCQPS---G 1634
+C A K G+ C C+PG VC
Sbjct: 757 PQMFLASCQAPKTFKSCSQSSENKFGAACAPTCQMLATGVACVPTKCEPGCVCAEGLYEN 816
Query: 1635 GILSCVTKDPC----HGVT----------CRPQETCKEQGGQGVCLPNYE--ATCWLWGD 1678
CV + C GV+ CR TC G+ C +TC L+G+
Sbjct: 817 ADGQCVPPEECPCEFSGVSYPGGAELHTDCR---TCSCSRGRWACQQGTHCPSTCTLYGE 873
Query: 1679 PHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVA 1738
H +FDG++F F G C Y+LAT C GV+ T F + T+N GN V+ R + +
Sbjct: 874 GHVITFDGQRFVFDGNCEYILATDVC-GVNDSQPT-FKILTENVICGNSGVTCSRAIKIF 931
Query: 1739 ALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWN 1798
G ++ + V G + + V G +S+ S + + L + ++ +
Sbjct: 932 LGGLSV-----VLADRNYTVTGEEPHVQLGVTPGALSLVVDIS---IPGRYNLTLIWNRH 983
Query: 1799 WRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDE 1858
+ + + + +CGLCGN + N +D + +A S SW+ PLC D
Sbjct: 984 MTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSWKE---SPLCGDV 1040
Query: 1859 CRGSCPTCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGG 1916
+ P C + + C + S T F TCH+ V +++ CV D C GG
Sbjct: 1041 SFVTDP-CSLNAFRRSWAERKCSVINSQT---FATCHSKVYHLPYYEACVRDACGCDSGG 1096
Query: 1917 DRDILCKALASYVAACQAAGVVIEDWRAQVGCEITC------PENSHYE---VCGPPC-- 1965
D + LC A+A+Y AC GV + DWR C I C ++ H E C
Sbjct: 1097 DCECLCDAVAAYAQACLDKGVCV-DWRTPAFCPIYCGFYNTHTQDGHGEYQYTQEANCTW 1155
Query: 1966 ---PASCPSPAPLTTPAVCEGPCVEGC-QC--DAGFVLSADRCVP 2004
P CPS P G +EGC C D F CVP
Sbjct: 1156 HYQPCLCPS-----QPQSVPGSNIEGCYNCSQDEYFDHEEGVCVP 1195
Score = 279 bits (714), Expect = 3e-74
Identities = 311/1237 (25%), Positives = 445/1237 (35%), Gaps = 225/1237 (18%)
Query: 1673 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYV 1732
C WG H+ +FD +DF GTCNY+ A T T F+V Q R P S
Sbjct: 45 CSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPT-----FSV----QLRRGPDGSIS 95
Query: 1733 RVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVADFGLQ 1792
R++ LG ++ + I V+ GV++ LP + ++G G S L+ L+
Sbjct: 96 RIIV--ELGASVVTVSEAIISVKDI--GVIS-LPYT-SNGLQITPFGQSVRLVAKQLELE 149
Query: 1793 VSYDW--NWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGT-LAPSIPIWGGSWRAP 1849
+ W + + V + Y G +CGLCGN D N+ V G L P P
Sbjct: 150 LEVVWGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEPHKFAALQKLDDP 209
Query: 1850 GWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVL 1909
G +C + P + Q + C L + V E F C
Sbjct: 210 G--EIC------TFQDIPSTHVRQAQHARICTQLLT-----LVAPECSVSKEPFVLSCQA 256
Query: 1910 DVCMGG--GDRDILCKALASYVAACQAAGVVIEDWRAQVGCEI-TCPENSHYEVCGPPCP 1966
DV G ++ C L+ Y C G + WR+ C + CP N Y+ CG C
Sbjct: 257 DVAAAPQPGPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSACV 316
Query: 1967 ASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSA----DRCVPLNNGCGCWANGTYHEAGS 2022
+C +P C C GC C G VL+ CVP+ C C +G + G
Sbjct: 317 KTCSNPQHS-----CSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQ-CPCVLHGAMYAPGE 370
Query: 2023 EFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHY 2082
A Q CRC G VCT C C G
Sbjct: 371 VTIA---ACQTCRCTLG--RWVCTERPC--------------------PGHCSLEGGSFV 405
Query: 2083 VTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHS 2142
T D + F GTC Y+L P L + + V ++ S + + +V
Sbjct: 406 TTFDARPYRFHGTCTYIL---LQSPQLPEDGALMAVYDKSGVSHSETSLVAVVYLSRQDK 462
Query: 2143 LTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVP 2202
+ +S + +G LP++ ++ + + + T+ GL L + V
Sbjct: 463 IVISQ--DEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVT 520
Query: 2203 AA--YAASLCGLCGNYNQDPADDLKAVGGKPAG--------WQVGGAQGCGECVSKPCPS 2252
+ GLCGN+N D DD G G W+ G E +
Sbjct: 521 VGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWRAGNCPAALERET----D 576
Query: 2253 PCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAV 2312
PC+ Q C ++ T CH V PA +++ C+ AC + +C A+
Sbjct: 577 PCSMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQACNYEETFPHICAAL 636
Query: 2313 ATYVAACQAAGAQLGEWRRP-DFCPLQCPAHSHYELCGDSCPVSCPSLS--APEGCESAC 2369
YV AC G L WR D C + C ++ + +C +C SLS A E SA
Sbjct: 637 GDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLSLSDRATECHHSAV 696
Query: 2370 R-EGCVC-DAGFVLSGDTCVPVGQCGCLHDGRYYPL----------------GEVFYP-- 2409
+GC C D ++ CV QC C+ +G + L G + P
Sbjct: 697 PVDGCNCPDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVINGITCHCINGRLSCPQR 756
Query: 2410 -------------------------GPECERRCE------------CGPGGHVTCQEG-- 2430
G C C+ C PG C EG
Sbjct: 757 PQMFLASCQAPKTFKSCSQSSENKFGAACAPTCQMLATGVACVPTKCEPG--CVCAEGLY 814
Query: 2431 ----AACGPHEECRLE-DGVQ---------ACHATGCGR--------------CLANGGI 2462
C P EEC E GV C C R C G
Sbjct: 815 ENADGQCVPPEECPCEFSGVSYPGGAELHTDCRTCSCSRGRWACQQGTHCPSTCTLYGEG 874
Query: 2463 HYITLDGRVYDLHGSCSYVLA-QVCHPKPGDEDFSIVLEK----NAAGDLQRLLVTVAGQ 2517
H IT DG+ + G+C Y+LA VC F I+ E N+ R + G
Sbjct: 875 HVITFDGQRFVFDGNCEYILATDVCGVNDSQPTFKILTENVICGNSGVTCSRAIKIFLGG 934
Query: 2518 VVSLAQGQQVTVDGEA--VALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIP 2575
+ + + TV GE V L V G + + + + + L L+++ +L+ I
Sbjct: 935 LSVVLADRNYTVTGEEPHVQLGVTPGALSLVVD---ISIPGRYNLTLIWNRHMTILIRIA 991
Query: 2576 SPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPV 2635
+ LCGLCGNFNGN DDF + ASS +W+ S CG+
Sbjct: 992 RASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSWK---ESPLCGDVSFV--TDP 1046
Query: 2636 CLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCA--QKGDKAFLCRS 2693
C + C + + FATC + + Y+ CV D C GD LC +
Sbjct: 1047 CSLNAFRRSWAERKCSVINSQ--TFATCHSKVYHLPYYEACVRDACGCDSGGDCECLCDA 1104
Query: 2694 LAAYTAACQAAGVAVKPWRTDSFCPLHCPAHS--------------------HYSICTRT 2733
+AAY AC GV V WRT +FCP++C ++ HY C
Sbjct: 1105 VAAYAQACLDKGVCV-DWRTPAFCPIYCGFYNTHTQDGHGEYQYTQEANCTWHYQPCLCP 1163
Query: 2734 CQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIP 2770
Q S + GC C D+ F +GVC+P
Sbjct: 1164 SQPQSVPGSNIEGC-----YNCSQDEYFDHEEGVCVP 1195
Score = 263 bits (672), Expect = 2e-69
Identities = 258/1054 (24%), Positives = 404/1054 (38%), Gaps = 195/1054 (18%)
Query: 2073 ECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTR 2132
+C WG H+ T D H +DF GTC Y+ +A C F+V + GS +
Sbjct: 44 QCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKD---AFPTFSVQLRRGPDGSIS----- 95
Query: 2133 SVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSL--A 2190
+ +++ +T+S + GV ++LP+ + L + +V L L
Sbjct: 96 RIIVELGASVVTVSEAIISVKDI-GV-ISLPYTSNGLQITPFGQSVRLVAKQLELELEVV 153
Query: 2191 FDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGA----QGCGE-C 2245
+ DS + + V Y +CGLCGN++ ++ + GK A GE C
Sbjct: 154 WGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEPHKFAALQKLDDPGEIC 213
Query: 2246 VSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLD--ACQVQG 2303
+ PS + Q + C + P V + C D A G
Sbjct: 214 TFQDIPSTHVRQAQHA----RICTQLLTLVAPECS----VSKEPFVLSCQADVAAAPQPG 265
Query: 2304 HPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPL-QCPAHSHYELCGDSCPVSCPSLSAP 2362
C ++ Y C G + WR P C + QCPA+ Y+ CG +C +C +
Sbjct: 266 PQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSACVKTCSN--PQ 323
Query: 2363 EGCESACREGCVCDAGFVLS----GDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCE 2418
C S+C GC C G VL+ TCVPV QC C+ G Y GEV
Sbjct: 324 HSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTI---------- 373
Query: 2419 CGPGGHVTCQEGAACGPHEECRLEDGVQACHATGC-GRCLANGGIHYITLDGRVYDLHGS 2477
AAC + CR G C C G C GG T D R Y HG+
Sbjct: 374 ------------AAC---QTCRCTLGRWVCTERPCPGHCSLEGGSFVTTFDARPYRFHGT 418
Query: 2478 CSYVLAQVCHPK-PGDEDFSIVLEKNAAGDLQRLLVTVA----GQVVSLAQGQQVTVDGE 2532
C+Y+L Q P+ P D V +K+ + LV V + ++Q + VT +GE
Sbjct: 419 CTYILLQ--SPQLPEDGALMAVYDKSGVSHSETSLVAVVYLSRQDKIVISQDEVVTNNGE 476
Query: 2533 AVALPVAVGRVRVTAE-GRNMVLQTTKGLRLLFDGDA--HLLMSIPSPFRGRLCGLCGNF 2589
A LP + V + ++ + T+ GL L+ +++ FRG+ GLCGNF
Sbjct: 477 AKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNF 536
Query: 2590 NGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEA 2649
NG+ +DDF G A + F +WRA CP L ET P ++
Sbjct: 537 NGDTTDDFTTSMGIAEGTASLFVDSWRAGN-------------CPAALERETDPCSMSQL 583
Query: 2650 --------CGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAAC 2701
C L F C A ++P+ ++++CVY C + +C +L Y AC
Sbjct: 584 NKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQACNYEETFPHICAALGDYVHAC 643
Query: 2702 QAAGVAVKPWRTD-SFCPLHCPAHSHYSICTRTCQGSCAALSG-LTGC--TTRCFEGCEC 2757
GV + WR+ C + C ++ +S ++ C+ +C +LS T C + +GC C
Sbjct: 644 SLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLSLSDRATECHHSAVPVDGCNC 703
Query: 2758 DDRFLLSQ-GVCIPVQDCGCTHNG-RYLPVNSSLLTSDCSERC----------------- 2798
D L+Q G C+ C C G +++ S + + + C
Sbjct: 704 PDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVINGITCHCINGRLSCPQRPQMFLAS 763
Query: 2799 --------SCSSSS-----------------GLTCQAAGCPPGRVC-------------- 2819
SCS SS G+ C C PG VC
Sbjct: 764 CQAPKTFKSCSQSSENKFGAACAPTCQMLATGVACVPTKCEPGCVCAEGLYENADGQCVP 823
Query: 2820 -----------------EVKAEARNCWATRG------------LCVLSVGANLTTFDGAR 2850
E+ + R C +RG C L ++ TFDG R
Sbjct: 824 PEECPCEFSGVSYPGGAELHTDCRTCSCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQR 883
Query: 2851 GATTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKG 2910
Y L++ G+ ++ P ++++ E IC + F G+ + ++
Sbjct: 884 FVFDGNCEYILATDVCGVNDSQPTFKILTENVICGNSGVTCSRAIKIFLGGLSVVLADRN 943
Query: 2911 VWVNGLRVDLPAEKLASV--SVSRTPDGSLLVRQKAGVQVWLGANGKVAVIVSNDHAGKL 2968
V G + P +L ++S D S+ R + +W + + + ++ L
Sbjct: 944 YTVTG---EEPHVQLGVTPGALSLVVDISIPGRYNLTL-IW-NRHMTILIRIARASQDPL 998
Query: 2969 CGACGNFDGDQTNDWHD------SQEKPAMEKWR 2996
CG CGNF+G+ +D+ S E + W+
Sbjct: 999 CGLCGNFNGNMKDDFETRSRYVASSELELVNSWK 1032
Score = 250 bits (639), Expect = 1e-65
Identities = 217/779 (27%), Positives = 330/779 (42%), Gaps = 96/779 (12%)
Query: 472 CRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRGS--RRVSYVG 529
C G H++TFD YD GTC+Y C D P FSV+ + GS R + +G
Sbjct: 45 CSTWGAGHFSTFDHHVYDFSGTCNYIFAATCK--DAFPTFSVQLRRGPDGSISRIIVELG 102
Query: 530 LVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVTY 589
V +S+ ++G + + + L ++ +R+ +E+V+G
Sbjct: 103 ASVVTVSEAIISVK--DIGVISLPYTSNGLQITPFGQSVRLVAKQLELELEVVWGP---- 156
Query: 590 DWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLC 649
D L + + ++ Q+CGLCGN++G ++F++ +G + +FA+ KLDD +C
Sbjct: 157 --DSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFL-EPHKFAALQKLDDPGEIC 213
Query: 650 EDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVV-- 707
+ P+ QAQH R+C L L P ++ PF+ C D+
Sbjct: 214 ---TFQDIPSTHVRQAQH---ARICTQLLTLVAP----ECSVSKEPFVLSCQADVAAAPQ 263
Query: 708 GGERLSLCRGLSAYAQACLELGISVGDWRSPANCPL-SCPANSRYELCGPACPTSCNGAA 766
G + S C LS Y++ C +G V WRSP C + CPAN Y+ CG AC +C+
Sbjct: 264 PGPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSACVKTCSN-- 321
Query: 767 APSNCSGRPCVEGCVCLPGFV----ASGGACVPASSCGCTFQGLQLAPGQEVWADELCQR 822
P + C GC C G V ++ CVP + C C G APG+ A CQ
Sbjct: 322 -PQHSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTIA--ACQ- 377
Query: 823 RCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDF 882
TC + C ++ CP G C G +FD R + F
Sbjct: 378 --TCRCTLGRWVCTER-PCP-------------------GHCSLEGGSFVTTFDARPYRF 415
Query: 883 MGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAVRVE--ARGVKVAVRREYPG 940
GTCTY+L+ Q+ LP L+ + + S T V V +R K+ + ++
Sbjct: 416 HGTCTYILL----QSPQLPEDGALMAVYDKSGVSHSETSLVAVVYLSRQDKIVISQD--E 469
Query: 941 QVLVDDVLQYLPFQAADGQVQVFRQ-GRDAVVRTDFGLTVTYD----WNARVTAKVPSSY 995
V + ++LP++ + + VFRQ + T FGL + + A VT V +
Sbjct: 470 VVTNNGEAKWLPYKTRN--ITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVT--VGPQF 525
Query: 996 AEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGC--GATEPGDCPKLDS 1053
GLCGNFNGD DD G A F +SW+ P T+P +L+
Sbjct: 526 RGQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWRAGNCPAALERETDPCSMSQLNK 585
Query: 1054 LVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYA 1113
+ A+ C +L F CH+ ++P + CVY C +C AL Y
Sbjct: 586 VCAE-----THCSMLLRTGTVFERCHATVNPAPFYKRCVYQACNYEETFPHICAALGDYV 640
Query: 1114 AACQAAGATVHPWRSE-ELCPLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSECH----- 1167
AC G + WRS + C + C ++ + S C +C L +ECH
Sbjct: 641 HACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLSL---SDRATECHHSAVP 697
Query: 1168 -EGCVCDEGFALSGE-SCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSC 1224
+GC C +G L+ + C+ A C C+ +G + G CHC G L SC
Sbjct: 698 VDGCNCPDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVINGI--TCHCINGRL-SC 753
Score = 169 bits (429), Expect = 3e-41
Identities = 157/578 (27%), Positives = 247/578 (42%), Gaps = 64/578 (11%)
Query: 2440 RLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVL 2499
RL+D Q A G+C G H+ T D VYD G+C+Y+ A C K FS+ L
Sbjct: 31 RLKDSPQT--APDKGQCSTWGAGHFSTFDHHVYDFSGTCNYIFAATC--KDAFPTFSVQL 86
Query: 2500 EKNAAGDLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVL---QT 2556
+ G + R++V + VV++++ D ++LP +++T G+++ L Q
Sbjct: 87 RRGPDGSISRIIVELGASVVTVSEAIISVKDIGVISLPYTSNGLQITPFGQSVRLVAKQL 146
Query: 2557 TKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWR 2616
L +++ D+HL++ + + G++CGLCGNF+G +++FV G F A +
Sbjct: 147 ELELEVVWGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEP-HKFAALQK 205
Query: 2617 APGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQC 2676
GE C Q P + + C QL P + +S + C
Sbjct: 206 LDDP----GEICTFQDIP---STHVRQAQHARICTQLLTLVAP----ECSVSKEPFVLSC 254
Query: 2677 VYDLCA--QKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPL-HCPAHSHYSICTRT 2733
D+ A Q G + C +L+ Y+ C G V+ WR+ C + CPA+ Y C
Sbjct: 255 QADVAAAPQPGPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSA 314
Query: 2734 CQGSCAALSGLTGCTTRCFEGCECDDRFLL----SQGVCIPVQDCGCT-HNGRYLPVNSS 2788
C +C+ + C++ C GC C + +L + C+PV C C H Y P +
Sbjct: 315 CVKTCS--NPQHSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVT 372
Query: 2789 LLTSDCSERCSCSSSSGLTCQAAGCPPGR-VCEVKAEARNCWATRGLCVLSVGANLTTFD 2847
+ CQ C GR VC R C G C L G+ +TTFD
Sbjct: 373 I----------------AACQTCRCTLGRWVC----TERPC---PGHCSLEGGSFVTTFD 409
Query: 2848 GARGATTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVGQVHIFFQDGMVTLTP 2907
Y L + P L V + + H +T V V++ QD +V ++
Sbjct: 410 ARPYRFHGTCTYIL-LQSPQLPEDGALMAVYDKSGVSHSETSLVAVVYLSRQDKIV-ISQ 467
Query: 2908 NKGVWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQ--VWLGANGKVAVIVSNDHA 2965
++ V NG LP K +++V R L + G++ V L + V V
Sbjct: 468 DEVVTNNGEAKWLP-YKTRNITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVTVGPQFR 526
Query: 2966 GKLCGACGNFDGDQTNDWHDSQ---EKPA---MEKWRA 2997
G+ G CGNF+GD T+D+ S E A ++ WRA
Sbjct: 527 GQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWRA 564
Score = 168 bits (426), Expect = 6e-41
Identities = 146/500 (29%), Positives = 210/500 (42%), Gaps = 82/500 (16%)
Query: 744 SCPANSRYELC--------GPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASG-GACV 794
SC A ++ C G AC +C A C C GCVC G + G CV
Sbjct: 763 SCQAPKTFKSCSQSSENKFGAACAPTCQMLATGVACVPTKCEPGCVCAEGLYENADGQCV 822
Query: 795 PASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLL 854
P C C F G+ G E+ D C R C+C+ R + +C G C
Sbjct: 823 PPEECPCEFSGVSYPGGAELHTD--C-RTCSCS--------RGRWACQQGTHCP------ 865
Query: 855 GCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGS-CGQNAALPAFRVLVENEHRG 913
TC G+ H ++FDG+RF F G C Y+L CG N + P F++L EN G
Sbjct: 866 -------STCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPTFKILTENVICG 918
Query: 914 SQTVSYTRAVRVEARGVKVAVR-REYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVR 972
+ V+ +RA+++ G+ V + R Y V ++ G + + D +
Sbjct: 919 NSGVTCSRAIKIFLGGLSVVLADRNYT----VTGEEPHVQLGVTPGALSLVV---DISIP 971
Query: 973 TDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSW 1032
+ LT+ ++ + + ++ + + LCGLCGNFNG+ DD R A++ L NSW
Sbjct: 972 GRYNLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSW 1031
Query: 1033 QEETRPGCG----ATEPGDCPKLDSLVA-QQLQSKNECGILADPKGPFRECHSKLDPQGA 1087
+E P CG T+P C SL A ++ ++ +C ++ F CHSK+
Sbjct: 1032 KES--PLCGDVSFVTDP--C----SLNAFRRSWAERKCSVINSQ--TFATCHSKVYHLPY 1081
Query: 1088 VRDCVYDRCLLP--GQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEAC 1145
CV D C G LCDA+A YA AC G V WR+ CP+ C ++ +
Sbjct: 1082 YEACVRDACGCDSGGDCECLCDAVAAYAQACLDKGVCV-DWRTPAFCPIYCGFYNTHTQD 1140
Query: 1146 SYG---------C-----PLSCGDLP--VPGGCGSECHEGCVCDEGFALSGESCLPLASC 1189
+G C P C P VPG C+ C DE F C+P
Sbjct: 1141 GHGEYQYTQEANCTWHYQPCLCPSQPQSVPGSNIEGCY-NCSQDEYFDHEEGVCVP---- 1195
Query: 1190 GCVHQGTYHPPGQTFYPGPG 1209
C+ T PP P G
Sbjct: 1196 -CMPPTTPQPPTTPQLPTTG 1214
Score = 135 bits (340), Expect = 6e-31
Identities = 119/435 (27%), Positives = 177/435 (40%), Gaps = 45/435 (10%)
Query: 450 AAGQRCQVVGGKAGCVAEST-AVCRAQGDPHYTTFDGRRYDMMGTCSYTMVEL--CSEDD 506
AA Q C+ G+ C C +G TTFD R Y GTC+Y +++ ED
Sbjct: 374 AACQTCRCTLGRWVCTERPCPGHCSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDG 433
Query: 507 TLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEG 566
L A ++ H + V+ V L + + +++ EV V N +
Sbjct: 434 ALMAVYDKSGVSHSETSLVAVVYL----SRQDKIVISQDEV----VTNNGEAKWLPYKTR 485
Query: 567 RLRVY-QSGPRAVVELVFGL--VVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFL 623
+ V+ Q+ + FGL VV Q +++ +F+ Q GLCGN+NGD DDF
Sbjct: 486 NITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFT 545
Query: 624 TPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGP 683
T G A F SW+ + C + C+ Q + C ML +
Sbjct: 546 TSMGIAEGTASLFVDSWRAGN----CPAALERETDPCSMSQLNKVCAETHCSMLLRTGTV 601
Query: 684 FAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPA-NCP 742
F CH T++P PF ++CVY C +C L Y AC G+ + WRS NC
Sbjct: 602 FERCHATVNPAPFYKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCT 661
Query: 743 LSCPANSRYELCGPACPTSC---NGAAAPSNCSGRPCVEGCVCLPG-FVASGGACVPASS 798
+ C N+ + AC +C + A + S P V+GC C G ++ G CV +
Sbjct: 662 IPCTGNTTFSYNSQACERTCLSLSDRATECHHSAVP-VDGCNCPDGTYLNQKGECVRKAQ 720
Query: 799 CGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTC---RDKQSCPAGERCSVQNGLLG 855
C C +G + L ++ NG +TC + SCP Q L
Sbjct: 721 CPCILEGYKFI---------LAEQSTVING----ITCHCINGRLSCPQ----RPQMFLAS 763
Query: 856 CY-PDRFGTCQGSGD 869
C P F +C S +
Sbjct: 764 CQAPKTFKSCSQSSE 778
Score = 127 bits (320), Expect = 1e-28
Identities = 108/383 (28%), Positives = 166/383 (43%), Gaps = 64/383 (16%)
Query: 444 CEGMQCAAGQ-RCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMV-EL 501
C C+ G+ CQ G ST C G+ H TFDG+R+ G C Y + ++
Sbjct: 846 CRTCSCSRGRWACQ-----QGTHCPST--CTLYGEGHVITFDGQRFVFDGNCEYILATDV 898
Query: 502 CSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDN------Q 555
C +D+ P F + +N G+ V+ S ++ + G + VL D +
Sbjct: 899 CGVNDSQPTFKILTENVICGNSGVTC---------SRAIKIFLGGLSVVLADRNYTVTGE 949
Query: 556 RSRLPVSLSEGRLRVYQSGPRAVVELV----FGLVVTYDWDCQLALSLPARFQDQVCGLC 611
+ + ++ G L + VV++ + L + ++ + + + QD +CGLC
Sbjct: 950 EPHVQLGVTPGALSL-------VVDISIPGRYNLTLIWNRHMTILIRIARASQDPLCGLC 1002
Query: 612 GNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGD 671
GN+NG+ DDF T +A +E +SWK LC D P C+ + +
Sbjct: 1003 GNFNGNMKDDFETRSRYVASSELELVNSWKESP---LCGDVSFVTDP-CSLNAFRRSWAE 1058
Query: 672 RLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVV--GGERLSLCRGLSAYAQACLELG 729
R C ++ FA CH + P+ E CV D C GG+ LC ++AYAQACL+ G
Sbjct: 1059 RKCSVIN--SQTFATCHSKVYHLPYYEACVRDACGCDSGGDCECLCDAVAAYAQACLDKG 1116
Query: 730 ISVGDWRSPANCPLSC--------PANSRYELCGPACPTSCNGAAAPSNCSGRP------ 775
+ V DWR+PA CP+ C + Y+ A +C P C +P
Sbjct: 1117 VCV-DWRTPAFCPIYCGFYNTHTQDGHGEYQYTQEA---NCTWHYQPCLCPSQPQSVPGS 1172
Query: 776 CVEGCV-CLPG--FVASGGACVP 795
+EGC C F G CVP
Sbjct: 1173 NIEGCYNCSQDEYFDHEEGVCVP 1195
>gi|239755545 PREDICTED: otogelin isoform 1 [Homo sapiens]
Length = 2852
Score = 310 bits (793), Expect = 2e-83
Identities = 311/1219 (25%), Positives = 449/1219 (36%), Gaps = 194/1219 (15%)
Query: 831 HQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLL 890
H C ++ G RC + + P+R C+ G H +FDG + G +Y L
Sbjct: 49 HPAFCDCRRFNATGPRCQM---VYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTL 105
Query: 891 VGSCGQNAALPAFRVLVENEHR-GSQTVSYTRAVR---VEARGVKVAVRREYPG-QVLVD 945
VG +F + V N+ + GS + +RAV V + + +A + G +V +
Sbjct: 106 VGRHEPEGQ--SFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLP 163
Query: 946 DVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGN 1005
V+ Q G V +VR T+ +D + V K+ GLCGN
Sbjct: 164 HVMGSARLQQLAGYV---------IVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGN 214
Query: 1006 FNGDPADDLALRGGGQAANALAFGNSWQEETR---PGCGATEPGDCPKLDSLVAQQLQSK 1062
N DP DDL G + + F +SWQE+ PG + P L
Sbjct: 215 NNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVY 274
Query: 1063 NECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGAT 1122
+C L P PF CH+ + P C D C G C ALA YA AC AG
Sbjct: 275 EQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRP 332
Query: 1123 VHPWRSE-ELCPLSCPPHSH-YEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSG 1180
+ WR++ C + C + Y C CP SC C +GC C G
Sbjct: 333 LQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFED 392
Query: 1181 ESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGG 1240
C+ A C C GT +PPG C++ C C G C ++ C
Sbjct: 393 GGCVAPAECPCEFHGTLYPPGSVVKED--CNT-CTCTSGKW-ECSTAVC----------- 437
Query: 1241 SLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAW 1300
+ C +GD H+TTFDGRR+ F TC Y+LA++ + F V +N
Sbjct: 438 --------PAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSS----GTFTVTLQNAPC 485
Query: 1301 GNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKL--------PVVLANGQIRASQH 1352
G + VQ + L + R+ D+ L P +IR
Sbjct: 486 GLNQDGA----CVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS- 540
Query: 1353 GSDVVIETDFGLRVAYD---LVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQA 1409
+ + T+ G+RV YD L Y++ V + + GLCG +NG+ +DDF P G
Sbjct: 541 SVFLRVRTNVGVRVLYDREGLRLYLQ--VDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPE 598
Query: 1410 GNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTG 1469
FGNSW+ + SP + +P P C L+ + C +L+
Sbjct: 599 STPQLFGNSWKTLSACSPLVSGSPLDP----------CDVHLQAASYSVQACSVLTGEM- 647
Query: 1470 PLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCP 1529
+ C + P + C D C G LC+ + Y C+ G V+ C
Sbjct: 648 -FAPCSAFLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACA 704
Query: 1530 MECPPNSHYELCADTCSLGCSALSAPPQC---------QDGCAEGCQCDSGFLYNGQA-- 1578
+ C + Y C C C L++P C +D C EGC C + QA
Sbjct: 705 LSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADL 764
Query: 1579 CVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEH----SCKPGQV----- 1629
CVP QC C+ GV Y P + + C C G M C +C GQV
Sbjct: 765 CVPRNQCSCHFQGVDYPPGDSDI--PSLGHCHCKDGV-MSCDSRAPAAACPAGQVFVNCS 821
Query: 1630 -------------CQPSGGILSCVTKDPC------------HGVTC-------------- 1650
C+ LS + PC HG C
Sbjct: 822 DLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKE 881
Query: 1651 --------RPQETCKEQGGQGVC-LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLAT 1701
P TC Q G C L +TC +GD HY +FDG FDF G C L
Sbjct: 882 YFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHL-- 939
Query: 1702 TGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGV 1761
V + F+V +N N + + + +++ +G ++ + D+ G
Sbjct: 940 -----VKSTSDVSFSVIVENVNCYSSGMICRKFISI-NVGNSLIVFDDDSG--------- 984
Query: 1762 LTALPVSVADGRISVAQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCG 1818
P S D + V + F + + +D V V + G + GLCG
Sbjct: 985 -NPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCG 1043
Query: 1819 NMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSC---PTCPEDRLEQYE 1875
N D N+ P + +G SW A EC + C + L +
Sbjct: 1044 NFDLKTINEMRTPENLELTNPQEFGSSWAAV--------ECPDTLDPRDMCVLNPLREPF 1095
Query: 1876 GPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDRDILCKALASYVAACQ 1933
C L S F CH V F+ C+ D C GGD + C ++++Y C
Sbjct: 1096 AKKECSILLSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCC 1152
Query: 1934 AAGVVIEDWRAQVGCEITC 1952
GV + DWR C C
Sbjct: 1153 QHGVAV-DWRTPRLCPYDC 1170
Score = 296 bits (758), Expect = 2e-79
Identities = 305/1176 (25%), Positives = 449/1176 (38%), Gaps = 199/1176 (16%)
Query: 1667 PNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNR-G 1725
P ++ C WG H +FDG + G +Y L P + F++ N + G
Sbjct: 73 PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS-----FSIQVHNDPQCG 127
Query: 1726 NPAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALL 1785
+ + R V++ +G IH + V G+ LP + R+ Q A ++
Sbjct: 128 SSPYTCSRAVSLFFVGEQ-EIHLAK----EVTHGGMRVQLPHVMGSARLQ--QLAGYVIV 180
Query: 1786 VADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGS 1845
+++D V + + G GLCGN + +P +D V +G L + + S
Sbjct: 181 RHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHS 240
Query: 1846 WR--APGWDPLCWDECRGSCPTCPEDRLEQYEGP--GFCGPLASGTGGPFTTCHAHVPPE 1901
W+ AP P S P P L+Q G G + PF CHA+V P
Sbjct: 241 WQEQAPNQPP---GPTTSSLPRPP--CLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPL 295
Query: 1902 SFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV-GCEITCPENSH-YE 1959
F C D+C GD C+ALA Y AC AG ++ WR Q+ C + C E + Y
Sbjct: 296 PFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYN 355
Query: 1960 VCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHE 2019
C CPASC P + E CV+GC C G + CV C C +GT +
Sbjct: 356 ECIACCPASC---HPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE-CPCEFHGTLYP 411
Query: 2020 AGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGD 2079
GS D C+ C C G C+ A C AEC GD
Sbjct: 412 PGSVVKED--CNT-CTC--TSGKWECSTAVC--------------------PAECSVTGD 446
Query: 2080 PHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTLQI 2138
H+ T DG R+ F TC+Y+L+ + FTVT+ N G +Q + +SV++ +
Sbjct: 447 IHFTTFDGRRYTFPATCQYILA-----KSRSSGTFTVTLQNAPCGLNQDGACVQSVSVIL 501
Query: 2139 Y---NHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDS 2195
+ +TL+ L D + P+ D+ LS + V T G+ + +D +
Sbjct: 502 HQDPRRQVTLTQAGD-VLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREG 560
Query: 2196 F-VRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQGCGECV 2246
+ L+V + GLCG +N + DD + G P W+ A C V
Sbjct: 561 LRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA--CSPLV 618
Query: 2247 SKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPG 2306
S PC Q + AC V+ T APC + P YF+ C DAC+ G P
Sbjct: 619 SGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDACRC-GQP- 674
Query: 2307 GLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEGC- 2365
LC +A Y C+ G + R C L C A Y C C +C L++PE C
Sbjct: 675 CLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACG 734
Query: 2366 --------ESACREGCVC--DAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPG----- 2410
C EGC C D D CVP QC C G YP G+ P
Sbjct: 735 VDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCH 794
Query: 2411 -----PECERRCECG--PGGHV-----------------TCQE----------------- 2429
C+ R P G V TC++
Sbjct: 795 CKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGC 854
Query: 2430 ---------GAACGPHEECRL----------EDGVQACHATGCGR-------------CL 2457
G AC EEC + + CH C R C
Sbjct: 855 ACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCT 914
Query: 2458 ANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEK---NAAGDLQRLLVTV 2514
A G HY T DG +D G+C L + D FS+++E ++G + R
Sbjct: 915 AYGDRHYRTFDGLPFDFVGACKVHLVK----STSDVSFSVIVENVNCYSSGMICR----- 965
Query: 2515 AGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGR-------NMVLQTTKGLRLLFDGD 2567
+ +S+ G + V + P + E +V + + LL+D
Sbjct: 966 --KFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQR 1023
Query: 2568 AHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEG 2627
+ + ++G+L GLCGNF+ ++ P ++ + FG++W A C +
Sbjct: 1024 TTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAA----VECPDT 1079
Query: 2628 CGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDL--CAQKG 2685
P+ +C+ + + C L + F C V+ + ++ C+ D C+Q G
Sbjct: 1080 LDPR--DMCVLNPLREPFAKKECSILLSE--VFEICHPVVDVTWFYSNCLTDTCGCSQGG 1135
Query: 2686 DKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHC 2721
D C S++AY C GVAV WRT CP C
Sbjct: 1136 DCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1170
Score = 280 bits (716), Expect = 2e-74
Identities = 247/825 (29%), Positives = 336/825 (40%), Gaps = 105/825 (12%)
Query: 450 AAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLP 509
A G RCQ+V E ++CRA G H TFDG Y + G SYT+V +
Sbjct: 60 ATGPRCQMVYNAG---PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQ-- 114
Query: 510 AFSVEAKNE-------HRGSRRVS--YVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLP 560
+FS++ N+ + SR VS +VG + + +T G R +LP
Sbjct: 115 SFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHL---AKEVTHG--------GMRVQLP 163
Query: 561 VSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPAD 620
+ RL+ Q +V + +D + + + GLCGN N DP D
Sbjct: 164 HVMGSARLQ--QLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKD 221
Query: 621 DFLTPDGALAPDAVEFASSWKLDDGDY--------LCEDGCQNNCPACTPGQAQHYEGDR 672
D +T G L D VEF SW+ + L C P G + E
Sbjct: 222 DLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEA-- 279
Query: 673 LCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISV 732
L PF CH + P PF C DLC G+ + CR L+ YA+AC + G +
Sbjct: 280 ------LLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 333
Query: 733 GDWRSP-ANCPLSCPANS-RYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASG 790
WR+ C + C + Y C CP SC+ A+ + S CV+GC C G +
Sbjct: 334 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVD-SEIACVDGCYCPNGLIFED 392
Query: 791 GACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQ 850
G CV + C C F G PG V D C CTC + + CPA CSV
Sbjct: 393 GGCVAPAECPCEFHGTLYPPGSVVKED--C-NTCTCTSGKWECS---TAVCPA--ECSV- 443
Query: 851 NGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENE 910
+GD H+ +FDGRR+ F TC Y+L S F V ++N
Sbjct: 444 ----------------TGDIHFTTFDGRRYTFPATCQYILAKSRSSG----TFTVTLQNA 483
Query: 911 HRG-SQTVSYTRAVRVEA-RGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRD 968
G +Q + ++V V + + V G VL+ D + +P D ++ R
Sbjct: 484 PCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIP-PYTDDAFEIRRLSSV 542
Query: 969 AV-VRTDFGLTVTYDWNA-RVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANAL 1026
+ VRT+ G+ V YD R+ +V + E GLCG FNG+ DD G +
Sbjct: 543 FLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQ 602
Query: 1027 AFGNSWQEETRPGCGATEPGD-CPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQ 1085
FGNSW +T C G D + S C +L F C + L P
Sbjct: 603 LFGNSW--KTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEM--FAPCSAFLSPV 658
Query: 1086 GAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEAC 1145
C D C GQ LC LA YA C+ G V C LSC Y C
Sbjct: 659 PYFEQCRRDACRC-GQP-CLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPC 716
Query: 1146 SYGCPLSCGDLPVPGGCG---------SECHEGCVC--DEGFALSGESCLPLASCGCVHQ 1194
C +C DL P CG EC EGC C D + C+P C C Q
Sbjct: 717 VAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQ 776
Query: 1195 GTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSG 1239
G +PPG + P G CHC++ G++SC+S + P AC P+G
Sbjct: 777 GVDYPPGDSDIPSLG---HCHCKD-GVMSCDSRA--PAAAC-PAG 814
Score = 254 bits (649), Expect = 9e-67
Identities = 233/821 (28%), Positives = 317/821 (38%), Gaps = 90/821 (10%)
Query: 2040 GGSLVCTPASCGLGEVCGLLPSGQ--HGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCE 2097
GG V PA C P Q + P + C+AWG H T DG + G
Sbjct: 44 GGECV-HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGS 102
Query: 2098 YLLSAPCHGPPLGAENFTVTVANEHR-GSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD 2156
Y L H P ++F++ V N+ + GS + +R+V+L +++
Sbjct: 103 YTLVGR-HEPE--GQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQ---EIHLAKEVTHG 156
Query: 2157 GVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNY 2216
G+ V LP + S L+G V+V S +LA+DG S V +++ GLCGN
Sbjct: 157 GMRVQLPHVMGSARLQQLAGY-VIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNN 215
Query: 2217 NQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCT------PEQQESFGGPDACGV 2270
N DP DDL GK V E P P T P Q++ G GV
Sbjct: 216 NADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQ--GV 273
Query: 2271 ISATDGPLAP----CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQL 2326
+ L P CH V P + C D CQ G C A+A Y AC AG L
Sbjct: 274 YEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 333
Query: 2327 GEWRRP-DFCPLQCPAHSH-YELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGD 2384
WR C + C + Y C CP SC ++ E AC +GC C G +
Sbjct: 334 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDG 393
Query: 2385 TCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDG 2444
CV +C C G YP PG + C C G
Sbjct: 394 GCVAPAECPCEFHGTLYP------PGSVVKEDCNT-------------------CTCTSG 428
Query: 2445 VQACHATGC-GRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNA 2503
C C C G IH+ T DGR Y +C Y+LA+ F++ L+
Sbjct: 429 KWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAK----SRSSGTFTVTLQNAP 484
Query: 2504 AG---------DLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVL 2554
G + +L + V+L Q V + + +P ++ L
Sbjct: 485 CGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFL 544
Query: 2555 Q--TTKGLRLLFDGDA-HLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETF 2611
+ T G+R+L+D + L + + + GLCG FNGN DDF+ P G S+ + F
Sbjct: 545 RVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLF 604
Query: 2612 GAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSE 2671
G +W+ + G C V L + A Y S +AC L FA C A LSP
Sbjct: 605 GNSWKTLSACSPLVSGSPLDPCDVHL--QAASY-SVQACSVLTGEM--FAPCSAFLSPVP 659
Query: 2672 YFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICT 2731
YF QC D C + + LC +LA Y C+ G+ V C L C A YS C
Sbjct: 660 YFEQCRRDAC--RCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCV 717
Query: 2732 RTCQGSCAALSGLTGC---------TTRCFEGCEC-DDRFLLSQG-VCIPVQDCGCTHNG 2780
C +C L+ C C EGC C D +L +Q +C+P C C G
Sbjct: 718 APCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQG 777
Query: 2781 RYLPVNSSLLTSDCSERCSCSS---SSGLTCQAAGCPPGRV 2818
P S + S C C S AA CP G+V
Sbjct: 778 VDYPPGDSDIPS--LGHCHCKDGVMSCDSRAPAAACPAGQV 816
Score = 161 bits (408), Expect = 8e-39
Identities = 154/588 (26%), Positives = 227/588 (38%), Gaps = 47/588 (7%)
Query: 2416 RCECGPGGHVTCQEGAACGPHE--ECRLEDGV----QACHATGCGR---CLANGGIHYIT 2466
R +C P +C G C +CR + Q + G R C A G H T
Sbjct: 30 RAKCAPSYLFSCFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVET 89
Query: 2467 LDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRL-------LVTVAGQVV 2519
DG Y L G SY L V +P + FSI + + L V Q +
Sbjct: 90 FDGLYYYLSGKGSYTL--VGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEI 147
Query: 2520 SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFR 2579
LA+ +VT G V LP +G R+ ++++ L +DG + + + +
Sbjct: 148 HLAK--EVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELL 205
Query: 2580 GRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAE 2639
G GLCGN N + DD V +G V F +W+ ++ G P CL +
Sbjct: 206 GWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQ 265
Query: 2640 ETAPYES-NEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYT 2698
+ E C L P PF C A +SP + C DLC GD A CR+LA Y
Sbjct: 266 NPGTMQGVYEQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYA 323
Query: 2699 AACQAAGVAVKPWRTD-SFCPLHCPAHSH-YSICTRTCQGSCAALSGLTGCTTRCFEGCE 2756
AC AG ++ WRT C +HC + Y+ C C SC + C +GC
Sbjct: 324 RACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCY 383
Query: 2757 CDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPG 2816
C + + G C+ +C C +G P S++ DC+ C+C+S C A CP
Sbjct: 384 CPNGLIFEDGGCVAPAECPCEFHGTLYP-PGSVVKEDCN-TCTCTSGK-WECSTAVCP-- 438
Query: 2817 RVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYR 2876
AE C ++ + TTFDG R + Y L+ T+
Sbjct: 439 ------AE----------CSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQN 482
Query: 2877 VVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDG 2936
+ ++V + VTLT V + +P + + R
Sbjct: 483 APCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSV 542
Query: 2937 SLLVRQKAGVQVWLGANG-KVAVIVSNDHAGKLCGACGNFDGDQTNDW 2983
L VR GV+V G ++ + V G CG F+G+ +D+
Sbjct: 543 FLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDF 590
Score = 115 bits (287), Expect = 9e-25
Identities = 111/421 (26%), Positives = 162/421 (38%), Gaps = 61/421 (14%)
Query: 729 GISVGDWRSPANCPLSCPANSRYELCGP-------ACPTSCNGAAAPSNCSGR-PCVEGC 780
G+ D R+PA +CPA + C + +C + S R PC+ GC
Sbjct: 798 GVMSCDSRAPA---AACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGC 854
Query: 781 VCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQS 840
C G + G AC C CT++G + PG +V + C C C + Q T S
Sbjct: 855 ACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSP--C-HTCVCQRGSFQCTLHPCAS 911
Query: 841 CPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL 900
TC GD HY +FDG FDF+G C LV S
Sbjct: 912 ----------------------TCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD---- 945
Query: 901 PAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADG-- 958
+F V+VEN + S + + + + + V DD P D
Sbjct: 946 VSFSVIVENVNCYSSGMICRKFISINVGNSLI---------VFDDDSGNPSPESFLDDKQ 996
Query: 959 QVQVFRQGRDAVVR-TDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALR 1017
+V +R G +V +T+ +D V + + L GLCGNF+ +++
Sbjct: 997 EVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTP 1056
Query: 1018 GGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRE 1077
+ N FG+SW P +P D L+ L ++ +K EC IL F
Sbjct: 1057 ENLELTNPQEFGSSWAAVECP--DTLDPRDMCVLNPL--REPFAKKECSILLSE--VFEI 1110
Query: 1078 CHSKLDPQGAVRDCVYDR--CLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLS 1135
CH +D +C+ D C G C +++ YA C G V WR+ LCP
Sbjct: 1111 CHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYD 1169
Query: 1136 C 1136
C
Sbjct: 1170 C 1170
Score = 98.6 bits (244), Expect = 8e-20
Identities = 82/297 (27%), Positives = 126/297 (42%), Gaps = 27/297 (9%)
Query: 455 CQVVGGKAGCVAESTA-VCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSV 513
C G C A C A GD HY TFDG +D +G C +V+ S+ +FSV
Sbjct: 895 CVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD----VSFSV 950
Query: 514 EAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQS 573
+N + Y + R + +S+ G V D+ + P S + + V+
Sbjct: 951 IVENVN------CYSSGMICRKF---ISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTW 1001
Query: 574 GPRAVVELVFGLV-VTYDWDCQLALSLPA--RFQDQVCGLCGNYNGDPADDFLTPDGALA 630
+ F +T WD + + + A ++Q Q+ GLCGN++ ++ TP+
Sbjct: 1002 RVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLEL 1061
Query: 631 PDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDT 690
+ EF SSW + C D C + + C +L L F +CH
Sbjct: 1062 TNPQEFGSSWAAVE----CPDTLDPR-DMCVLNPLREPFAKKECSIL--LSEVFEICHPV 1114
Query: 691 LDPRPFLEQCVYDL--CVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSC 745
+D F C+ D C GG+ C +SAYA C + G++V DWR+P CP C
Sbjct: 1115 VDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1170
Score = 92.4 bits (228), Expect = 6e-18
Identities = 117/502 (23%), Positives = 189/502 (37%), Gaps = 87/502 (17%)
Query: 2355 SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLH----DGRYYPLGEVFYPG 2410
S P+LS EG A + + TCVP+ + C+ +G+ + + +
Sbjct: 1953 SAPALSIVEGLAEALATTTEAN-----TSTTCVPIAEQDCVRHICLEGQLIRVNQSQHC- 2006
Query: 2411 PECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGR 2470
P+ CG G G C P EC AC RC + ++T DG
Sbjct: 2007 PQGAAPPRCGILGLAVRVGGDRCCPLWEC-------AC------RCSIFPDLSFVTFDGS 2053
Query: 2471 VYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRL-----------LVTVAGQVV 2519
L Y+L+Q DE ++ + + +L L + +A QV
Sbjct: 2054 HVALFKEAIYILSQ-----SPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVT 2108
Query: 2520 SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLM---SIPS 2576
++VTVD + V PV+ R+ G ++ T +++ + + L++ S S
Sbjct: 2109 IDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTS 2168
Query: 2577 PFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVET---FGAAWRAPGSSKGCGE------G 2627
+G GLCG +G+ ++D L +GS E F +W+ P S G+
Sbjct: 2169 KAQGH--GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDS 2226
Query: 2628 CGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDK 2687
C C CL + AC + P+ + C+ + ++Y +Q
Sbjct: 2227 CATTDCSPCL--RMVSNRTFSACHRFVPPE---SFCELWIRDTKYVQQP----------- 2270
Query: 2688 AFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTG- 2746
C +L Y A C V ++ WR +CP C + S Y C C+ G+ G
Sbjct: 2271 ---CVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGP 2326
Query: 2747 -----CTTRCFEGCECDDRFLLSQ---GVCIPVQDCGCTHN---GRYLPVNSSLLTSDCS 2795
C EGC C + +L + +CIP C CT + R L + S C
Sbjct: 2327 LDPEHCQV-LGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCC 2385
Query: 2796 ERCSCSSSSGLTCQAAGCPPGR 2817
+ C + + GCP R
Sbjct: 2386 QH-QCQAPDTIVPVDLGCPSPR 2406
Score = 91.3 bits (225), Expect = 1e-17
Identities = 115/456 (25%), Positives = 171/456 (37%), Gaps = 78/456 (17%)
Query: 419 GLAKAIGYATAADCGRTVLSPVEPSCEGMQCAAGQ-----------------RCQV---- 457
GLA+A+ T A+ T + E C C GQ RC +
Sbjct: 1962 GLAEALATTTEANTSTTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLA 2021
Query: 458 --VGGKAGC-VAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVE 514
VGG C + E C D + TFDG + Y + + S D+ L ++
Sbjct: 2022 VRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQ--SPDEMLTVHVLD 2079
Query: 515 AKNEHRGSRRVSYVGLVTVRA--YSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQ 572
K+ + G LV + +H V++ R V VD Q PVS R+
Sbjct: 2080 CKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRK-VTVDLQPVWPPVS--RYGFRIED 2136
Query: 573 SGPRAVVELVFGLVVTYDWDCQLALSLPARFQD-QVCGLCGNYNGDPADDFLTPDGAL-- 629
+G ++ + + + L + ++ Q GLCG +GD A+D DG++
Sbjct: 2137 TGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVG 2196
Query: 630 -APDAVEFASSWKLDDG------DYLCEDGCQN-NCPACTPGQAQHYEGDRLCGMLTKLD 681
A D F SW++ D C +C C R+ T
Sbjct: 2197 GAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCL----------RMVSNRT--- 2243
Query: 682 GPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANC 741
F+ CH + P F E + D V C L+ Y C + + + +WR C
Sbjct: 2244 --FSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCI-EWRRSDYC 2296
Query: 742 PLSCPANSRYELCGPAC--PTSCN----GAAAPSNCSGRPCVEGCVCLPGFV---ASGGA 792
P C ++S Y+ C AC P +C G P +C + EGCVC G +
Sbjct: 2297 PFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHC--QVLGEGCVCSEGTILHRRHSAL 2354
Query: 793 CVPASSCGCT-FQGLQLAPGQEVWADEL---CQRRC 824
C+P + C CT G+ A G E W L CQ +C
Sbjct: 2355 CIPEAKCACTDSMGVPRALG-ETWNSSLSGCCQHQC 2389
Score = 90.1 bits (222), Expect = 3e-17
Identities = 121/509 (23%), Positives = 184/509 (36%), Gaps = 82/509 (16%)
Query: 1216 CQEGGLVSCESSSCGPHEACQPSGGSLG---------CVAVGSSTCQAS--GDPHYTTFD 1264
C EG L+ S P A P G LG C + C+ S D + TFD
Sbjct: 1992 CLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFD 2051
Query: 1265 GRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQ 1324
G +Y+L+Q+ +H N+ N ++ + + +++
Sbjct: 2052 GSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDR 2111
Query: 1325 RQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQ 1384
KVTV+ + PV +I + H ++ +D ++ + + V
Sbjct: 2112 FNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMI-VEASKTSKA 2170
Query: 1385 QMCGLCGNYNGDPKDDFQKPNGSQAGNANE---FGNSWEEVVPDSPCLPPTPCPPGSEDC 1441
Q GLCG +GD +D +GS G A + F +SW+ VP S L D
Sbjct: 2171 QGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQ--VPSS--LTSVGQTRFRPDS 2226
Query: 1442 IPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSIL 1501
+ C P L ++S+ T S+CH+ V P+ + I D +
Sbjct: 2227 CATTDCSPCLR----------MVSNRT--FSACHRFVPPESFCELWIRDTKY----VQQP 2270
Query: 1502 CSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDG 1561
C + YV+ C +E WR +CP C +S Y+ C C P CQDG
Sbjct: 2271 CVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTAC-------EPPKTCQDG 2322
Query: 1562 ------------CAEGCQCDSGFLY---NGQACVPIQQCGCYHN-GV---YYEPEQTVLI 1602
EGC C G + + C+P +C C + GV E + L
Sbjct: 2323 ILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLS 2382
Query: 1603 DNCRQQCTCHAGKGMVCQEHSC---KPGQVCQPSGGILSCVTKDP-------------CH 1646
C+ Q C A +V + C +P + L TKDP C
Sbjct: 2383 GCCQHQ--CQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCE 2440
Query: 1647 GV--TCRPQETCKEQGGQGVCLPNYEATC 1673
G+ TCRP + C P+Y C
Sbjct: 2441 GLAPTCRPGHRLLTHFQEDSCCPSYSCEC 2469
Score = 84.7 bits (208), Expect = 1e-15
Identities = 105/415 (25%), Positives = 157/415 (37%), Gaps = 79/415 (19%)
Query: 2047 PASCGLGEVCGL-LPSGQHGCQPV--STAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAP 2103
P CG + GL + G C P+ C + D +VT DG Y+LS
Sbjct: 2012 PPRCG---ILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS 2068
Query: 2104 -----------CHGPPLGAEN---FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSAR- 2148
C LG N F + + N VT+ +N +T+ +
Sbjct: 2069 PDEMLTVHVLDCKSANLGHLNWPPFCLVMLN------MTHLAHQVTIDRFNRKVTVDLQP 2122
Query: 2149 -WPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRL----RVPA 2203
WP + F+++ H ++ + T S + + + S + + +
Sbjct: 2123 VWPPVSRYG-------FRIEDTGHMYM------ILTPSDIQIQWLHSSGLMIVEASKTSK 2169
Query: 2204 AYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECV-SKPCPSPCTPEQQESF 2262
A LCG+C D A+DL G VGGA+ + S PS T Q F
Sbjct: 2170 AQGHGLCGICDG---DAANDLTLKDGSV----VGGAEDPAPFLDSWQVPSSLTSVGQTRF 2222
Query: 2263 GGPDACGVISAT-------DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATY 2315
PD+C + + + CH VPP + + + D VQ C A+ Y
Sbjct: 2223 R-PDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVY 2277
Query: 2316 VAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSC--PVSCP----SLSAPEGCESAC 2369
VA C + EWRR D+CP C + S Y+ C +C P +C PE C+
Sbjct: 2278 VAMCHKFHVCI-EWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQ-VL 2335
Query: 2370 REGCVCDAGFVL---SGDTCVPVGQCGCLHD-GRYYPLGEVFYPGPE--CERRCE 2418
EGCVC G +L C+P +C C G LGE + C+ +C+
Sbjct: 2336 GEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQ 2390
Score = 78.6 bits (192), Expect = 9e-14
Identities = 119/493 (24%), Positives = 165/493 (33%), Gaps = 111/493 (22%)
Query: 816 ADELCQRRCTCNGATHQVTCRDKQSCPAGE---RCSVQNGLLG---------CYPDRFGT 863
A++ C R G +V Q CP G RC G+LG C P
Sbjct: 1983 AEQDCVRHICLEGQLIRVN--QSQHCPQGAAPPRC----GILGLAVRVGGDRCCPLWECA 2036
Query: 864 CQGS--GDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL----------------PAFRV 905
C+ S D +V+FDG Y+L S + + P V
Sbjct: 2037 CRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLV 2096
Query: 906 LVENEHRGSQTV--SYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVF 963
++ H Q + R V V+ + V V R G + D Y+ +D Q+Q
Sbjct: 2097 MLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRY--GFRIEDTGHMYMILTPSDIQIQWL 2154
Query: 964 RQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGG---G 1020
+V +K + LCG+C +GD A+DL L+ G G
Sbjct: 2155 HSSGLMIVEA---------------SKTSKAQGHGLCGIC---DGDAANDLTLKDGSVVG 2196
Query: 1021 QAANALAFGNSWQEE---TRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRE 1077
A + F +SWQ T G P C D ++ S F
Sbjct: 2197 GAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRT----------FSA 2246
Query: 1078 CHSKLDPQGA----VRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCP 1133
CH + P+ +RD Y + C AL Y A C + WR + CP
Sbjct: 2247 CHRFVPPESFCELWIRDTKYVQ--------QPCVALTVYVAMCHKFHVCIE-WRRSDYCP 2297
Query: 1134 LSCPPHSHYEACSYGC--PLSCGDLPVPGGCGSECH---EGCVCDEGFAL---SGESCLP 1185
C S Y+AC C P +C D + C EGCVC EG L C+P
Sbjct: 2298 FLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIP 2357
Query: 1186 LASCGCV-HQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGC 1244
A C C G G+T+ L C C + P LGC
Sbjct: 2358 EAKCACTDSMGVPRALGETW-------------NSSLSGCCQHQCQAPDTIVPV--DLGC 2402
Query: 1245 VAVGSSTCQASGD 1257
+ +C G+
Sbjct: 2403 PSPRPESCLRFGE 2415
Score = 63.9 bits (154), Expect = 2e-09
Identities = 113/434 (26%), Positives = 158/434 (36%), Gaps = 67/434 (15%)
Query: 1665 CLPNYEATCW--LWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQ 1722
C P +E C ++ D + +FDG Y+L+ + + LT + K+
Sbjct: 2029 CCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS-----PDEMLTVHVLDCKSA 2083
Query: 1723 NRGN---PAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQG 1779
N G+ P V ++ + L ++I + KV V + V PVS RI
Sbjct: 2084 NLGHLNWPPFCLV-MLNMTHLAHQVTIDRFN-RKVTVDLQPVWP--PVSRYGFRIEDTGH 2139
Query: 1780 ASKALLVADFGLQVSYDWNWR-VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTL--- 1835
L +D +Q + V+ + S G GLCG D + ND +G++
Sbjct: 2140 MYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLKDGSVVGG 2197
Query: 1836 ----APSIPIWG--GSWRAPGWDPLCWDECRGS-CPTCPEDRLEQYEGPGFCGPLASGTG 1888
AP + W S + G D C + C C L +
Sbjct: 2198 AEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPC----------------LRMVSN 2241
Query: 1889 GPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGC 1948
F+ CH VPPESF + + D C AL YVA C V IE WR C
Sbjct: 2242 RTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCIE-WRRSDYC 2296
Query: 1949 EITCPENSHYEVCGPPC--PASCPSP--APLTTPAVCEGPCVEGCQCDAGFVL---SADR 2001
C +S Y+ C C P +C PL P C+ EGC C G +L +
Sbjct: 2297 PFLCSSDSTYQACVTACEPPKTCQDGILGPL-DPEHCQ-VLGEGCVCSEGTILHRRHSAL 2354
Query: 2002 CVPLNNGCGCWANGTYHEAGSEFW---ADGTCSQWCRCGP-----GGGSLVCTPASC-GL 2052
C+P C C + A E W G C C+ G P SC
Sbjct: 2355 CIP-EAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRF 2413
Query: 2053 GEVCGLLPSGQHGC 2066
GEV LLP+ C
Sbjct: 2414 GEVALLLPTKDPCC 2427
Score = 32.7 bits (73), Expect = 5.6
Identities = 26/96 (27%), Positives = 33/96 (34%), Gaps = 17/96 (17%)
Query: 2721 CPAHSHYSICT-----------RTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCI 2769
CPA + C+ RTC+ LS C GC C L C
Sbjct: 811 CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLS--VSARGPCLSGCACPQGLLRHGDACF 868
Query: 2770 PVQDCGCTHNGR-YLPVNSSLLTSDCSERCSCSSSS 2804
++C CT G+ Y P + S C C C S
Sbjct: 869 LPEECPCTWKGKEYFP--GDQVMSPC-HTCVCQRGS 901
>gi|239755543 PREDICTED: otogelin isoform 2 [Homo sapiens]
Length = 2924
Score = 310 bits (793), Expect = 2e-83
Identities = 311/1219 (25%), Positives = 449/1219 (36%), Gaps = 194/1219 (15%)
Query: 831 HQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLL 890
H C ++ G RC + + P+R C+ G H +FDG + G +Y L
Sbjct: 121 HPAFCDCRRFNATGPRCQM---VYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTL 177
Query: 891 VGSCGQNAALPAFRVLVENEHR-GSQTVSYTRAVR---VEARGVKVAVRREYPG-QVLVD 945
VG +F + V N+ + GS + +RAV V + + +A + G +V +
Sbjct: 178 VGRHEPEGQ--SFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLP 235
Query: 946 DVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGN 1005
V+ Q G V +VR T+ +D + V K+ GLCGN
Sbjct: 236 HVMGSARLQQLAGYV---------IVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGN 286
Query: 1006 FNGDPADDLALRGGGQAANALAFGNSWQEETR---PGCGATEPGDCPKLDSLVAQQLQSK 1062
N DP DDL G + + F +SWQE+ PG + P L
Sbjct: 287 NNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVY 346
Query: 1063 NECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGAT 1122
+C L P PF CH+ + P C D C G C ALA YA AC AG
Sbjct: 347 EQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRP 404
Query: 1123 VHPWRSE-ELCPLSCPPHSH-YEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSG 1180
+ WR++ C + C + Y C CP SC C +GC C G
Sbjct: 405 LQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFED 464
Query: 1181 ESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGG 1240
C+ A C C GT +PPG C++ C C G C ++ C
Sbjct: 465 GGCVAPAECPCEFHGTLYPPGSVVKED--CNT-CTCTSGKW-ECSTAVC----------- 509
Query: 1241 SLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAW 1300
+ C +GD H+TTFDGRR+ F TC Y+LA++ + F V +N
Sbjct: 510 --------PAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSS----GTFTVTLQNAPC 557
Query: 1301 GNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKL--------PVVLANGQIRASQH 1352
G + VQ + L + R+ D+ L P +IR
Sbjct: 558 GLNQDGA----CVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS- 612
Query: 1353 GSDVVIETDFGLRVAYD---LVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQA 1409
+ + T+ G+RV YD L Y++ V + + GLCG +NG+ +DDF P G
Sbjct: 613 SVFLRVRTNVGVRVLYDREGLRLYLQ--VDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPE 670
Query: 1410 GNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTG 1469
FGNSW+ + SP + +P P C L+ + C +L+
Sbjct: 671 STPQLFGNSWKTLSACSPLVSGSPLDP----------CDVHLQAASYSVQACSVLTGEM- 719
Query: 1470 PLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCP 1529
+ C + P + C D C G LC+ + Y C+ G V+ C
Sbjct: 720 -FAPCSAFLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACA 776
Query: 1530 MECPPNSHYELCADTCSLGCSALSAPPQC---------QDGCAEGCQCDSGFLYNGQA-- 1578
+ C + Y C C C L++P C +D C EGC C + QA
Sbjct: 777 LSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADL 836
Query: 1579 CVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEH----SCKPGQV----- 1629
CVP QC C+ GV Y P + + C C G M C +C GQV
Sbjct: 837 CVPRNQCSCHFQGVDYPPGDSDI--PSLGHCHCKDGV-MSCDSRAPAAACPAGQVFVNCS 893
Query: 1630 -------------CQPSGGILSCVTKDPC------------HGVTC-------------- 1650
C+ LS + PC HG C
Sbjct: 894 DLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKE 953
Query: 1651 --------RPQETCKEQGGQGVC-LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLAT 1701
P TC Q G C L +TC +GD HY +FDG FDF G C L
Sbjct: 954 YFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHL-- 1011
Query: 1702 TGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGV 1761
V + F+V +N N + + + +++ +G ++ + D+ G
Sbjct: 1012 -----VKSTSDVSFSVIVENVNCYSSGMICRKFISI-NVGNSLIVFDDDSG--------- 1056
Query: 1762 LTALPVSVADGRISVAQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCG 1818
P S D + V + F + + +D V V + G + GLCG
Sbjct: 1057 -NPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCG 1115
Query: 1819 NMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSC---PTCPEDRLEQYE 1875
N D N+ P + +G SW A EC + C + L +
Sbjct: 1116 NFDLKTINEMRTPENLELTNPQEFGSSWAAV--------ECPDTLDPRDMCVLNPLREPF 1167
Query: 1876 GPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDRDILCKALASYVAACQ 1933
C L S F CH V F+ C+ D C GGD + C ++++Y C
Sbjct: 1168 AKKECSILLSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCC 1224
Query: 1934 AAGVVIEDWRAQVGCEITC 1952
GV + DWR C C
Sbjct: 1225 QHGVAV-DWRTPRLCPYDC 1242
Score = 296 bits (758), Expect = 2e-79
Identities = 305/1176 (25%), Positives = 449/1176 (38%), Gaps = 199/1176 (16%)
Query: 1667 PNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNR-G 1725
P ++ C WG H +FDG + G +Y L P + F++ N + G
Sbjct: 145 PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS-----FSIQVHNDPQCG 199
Query: 1726 NPAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALL 1785
+ + R V++ +G IH + V G+ LP + R+ Q A ++
Sbjct: 200 SSPYTCSRAVSLFFVGEQ-EIHLAK----EVTHGGMRVQLPHVMGSARLQ--QLAGYVIV 252
Query: 1786 VADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGS 1845
+++D V + + G GLCGN + +P +D V +G L + + S
Sbjct: 253 RHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHS 312
Query: 1846 WR--APGWDPLCWDECRGSCPTCPEDRLEQYEGP--GFCGPLASGTGGPFTTCHAHVPPE 1901
W+ AP P S P P L+Q G G + PF CHA+V P
Sbjct: 313 WQEQAPNQPP---GPTTSSLPRPP--CLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPL 367
Query: 1902 SFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV-GCEITCPENSH-YE 1959
F C D+C GD C+ALA Y AC AG ++ WR Q+ C + C E + Y
Sbjct: 368 PFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYN 427
Query: 1960 VCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHE 2019
C CPASC P + E CV+GC C G + CV C C +GT +
Sbjct: 428 ECIACCPASC---HPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE-CPCEFHGTLYP 483
Query: 2020 AGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGD 2079
GS D C+ C C G C+ A C AEC GD
Sbjct: 484 PGSVVKED--CNT-CTC--TSGKWECSTAVC--------------------PAECSVTGD 518
Query: 2080 PHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTLQI 2138
H+ T DG R+ F TC+Y+L+ + FTVT+ N G +Q + +SV++ +
Sbjct: 519 IHFTTFDGRRYTFPATCQYILA-----KSRSSGTFTVTLQNAPCGLNQDGACVQSVSVIL 573
Query: 2139 Y---NHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDS 2195
+ +TL+ L D + P+ D+ LS + V T G+ + +D +
Sbjct: 574 HQDPRRQVTLTQAGD-VLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREG 632
Query: 2196 F-VRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQGCGECV 2246
+ L+V + GLCG +N + DD + G P W+ A C V
Sbjct: 633 LRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA--CSPLV 690
Query: 2247 SKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPG 2306
S PC Q + AC V+ T APC + P YF+ C DAC+ G P
Sbjct: 691 SGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDACRC-GQP- 746
Query: 2307 GLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEGC- 2365
LC +A Y C+ G + R C L C A Y C C +C L++PE C
Sbjct: 747 CLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACG 806
Query: 2366 --------ESACREGCVC--DAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPG----- 2410
C EGC C D D CVP QC C G YP G+ P
Sbjct: 807 VDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCH 866
Query: 2411 -----PECERRCECG--PGGHV-----------------TCQE----------------- 2429
C+ R P G V TC++
Sbjct: 867 CKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGC 926
Query: 2430 ---------GAACGPHEECRL----------EDGVQACHATGCGR-------------CL 2457
G AC EEC + + CH C R C
Sbjct: 927 ACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCT 986
Query: 2458 ANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEK---NAAGDLQRLLVTV 2514
A G HY T DG +D G+C L + D FS+++E ++G + R
Sbjct: 987 AYGDRHYRTFDGLPFDFVGACKVHLVK----STSDVSFSVIVENVNCYSSGMICR----- 1037
Query: 2515 AGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGR-------NMVLQTTKGLRLLFDGD 2567
+ +S+ G + V + P + E +V + + LL+D
Sbjct: 1038 --KFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQR 1095
Query: 2568 AHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEG 2627
+ + ++G+L GLCGNF+ ++ P ++ + FG++W A C +
Sbjct: 1096 TTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAA----VECPDT 1151
Query: 2628 CGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDL--CAQKG 2685
P+ +C+ + + C L + F C V+ + ++ C+ D C+Q G
Sbjct: 1152 LDPR--DMCVLNPLREPFAKKECSILLSE--VFEICHPVVDVTWFYSNCLTDTCGCSQGG 1207
Query: 2686 DKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHC 2721
D C S++AY C GVAV WRT CP C
Sbjct: 1208 DCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1242
Score = 280 bits (716), Expect = 2e-74
Identities = 247/825 (29%), Positives = 336/825 (40%), Gaps = 105/825 (12%)
Query: 450 AAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLP 509
A G RCQ+V E ++CRA G H TFDG Y + G SYT+V +
Sbjct: 132 ATGPRCQMVYNAG---PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQ-- 186
Query: 510 AFSVEAKNE-------HRGSRRVS--YVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLP 560
+FS++ N+ + SR VS +VG + + +T G R +LP
Sbjct: 187 SFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHL---AKEVTHG--------GMRVQLP 235
Query: 561 VSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPAD 620
+ RL+ Q +V + +D + + + GLCGN N DP D
Sbjct: 236 HVMGSARLQ--QLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKD 293
Query: 621 DFLTPDGALAPDAVEFASSWKLDDGDY--------LCEDGCQNNCPACTPGQAQHYEGDR 672
D +T G L D VEF SW+ + L C P G + E
Sbjct: 294 DLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEA-- 351
Query: 673 LCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISV 732
L PF CH + P PF C DLC G+ + CR L+ YA+AC + G +
Sbjct: 352 ------LLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 405
Query: 733 GDWRSP-ANCPLSCPANS-RYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASG 790
WR+ C + C + Y C CP SC+ A+ + S CV+GC C G +
Sbjct: 406 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVD-SEIACVDGCYCPNGLIFED 464
Query: 791 GACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQ 850
G CV + C C F G PG V D C CTC + + CPA CSV
Sbjct: 465 GGCVAPAECPCEFHGTLYPPGSVVKED--C-NTCTCTSGKWECS---TAVCPA--ECSV- 515
Query: 851 NGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENE 910
+GD H+ +FDGRR+ F TC Y+L S F V ++N
Sbjct: 516 ----------------TGDIHFTTFDGRRYTFPATCQYILAKSRSSG----TFTVTLQNA 555
Query: 911 HRG-SQTVSYTRAVRVEA-RGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRD 968
G +Q + ++V V + + V G VL+ D + +P D ++ R
Sbjct: 556 PCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIP-PYTDDAFEIRRLSSV 614
Query: 969 AV-VRTDFGLTVTYDWNA-RVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANAL 1026
+ VRT+ G+ V YD R+ +V + E GLCG FNG+ DD G +
Sbjct: 615 FLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQ 674
Query: 1027 AFGNSWQEETRPGCGATEPGD-CPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQ 1085
FGNSW +T C G D + S C +L F C + L P
Sbjct: 675 LFGNSW--KTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEM--FAPCSAFLSPV 730
Query: 1086 GAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEAC 1145
C D C GQ LC LA YA C+ G V C LSC Y C
Sbjct: 731 PYFEQCRRDACRC-GQP-CLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPC 788
Query: 1146 SYGCPLSCGDLPVPGGCG---------SECHEGCVC--DEGFALSGESCLPLASCGCVHQ 1194
C +C DL P CG EC EGC C D + C+P C C Q
Sbjct: 789 VAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQ 848
Query: 1195 GTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSG 1239
G +PPG + P G CHC++ G++SC+S + P AC P+G
Sbjct: 849 GVDYPPGDSDIPSLG---HCHCKD-GVMSCDSRA--PAAAC-PAG 886
Score = 254 bits (649), Expect = 9e-67
Identities = 233/821 (28%), Positives = 317/821 (38%), Gaps = 90/821 (10%)
Query: 2040 GGSLVCTPASCGLGEVCGLLPSGQ--HGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCE 2097
GG V PA C P Q + P + C+AWG H T DG + G
Sbjct: 116 GGECV-HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGS 174
Query: 2098 YLLSAPCHGPPLGAENFTVTVANEHR-GSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD 2156
Y L H P ++F++ V N+ + GS + +R+V+L +++
Sbjct: 175 YTLVGR-HEPE--GQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQ---EIHLAKEVTHG 228
Query: 2157 GVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNY 2216
G+ V LP + S L+G V+V S +LA+DG S V +++ GLCGN
Sbjct: 229 GMRVQLPHVMGSARLQQLAGY-VIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNN 287
Query: 2217 NQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCT------PEQQESFGGPDACGV 2270
N DP DDL GK V E P P T P Q++ G GV
Sbjct: 288 NADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQ--GV 345
Query: 2271 ISATDGPLAP----CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQL 2326
+ L P CH V P + C D CQ G C A+A Y AC AG L
Sbjct: 346 YEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 405
Query: 2327 GEWRRP-DFCPLQCPAHSH-YELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGD 2384
WR C + C + Y C CP SC ++ E AC +GC C G +
Sbjct: 406 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDG 465
Query: 2385 TCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDG 2444
CV +C C G YP PG + C C G
Sbjct: 466 GCVAPAECPCEFHGTLYP------PGSVVKEDCNT-------------------CTCTSG 500
Query: 2445 VQACHATGC-GRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNA 2503
C C C G IH+ T DGR Y +C Y+LA+ F++ L+
Sbjct: 501 KWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAK----SRSSGTFTVTLQNAP 556
Query: 2504 AG---------DLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVL 2554
G + +L + V+L Q V + + +P ++ L
Sbjct: 557 CGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFL 616
Query: 2555 Q--TTKGLRLLFDGDA-HLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETF 2611
+ T G+R+L+D + L + + + GLCG FNGN DDF+ P G S+ + F
Sbjct: 617 RVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLF 676
Query: 2612 GAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSE 2671
G +W+ + G C V L + A Y S +AC L FA C A LSP
Sbjct: 677 GNSWKTLSACSPLVSGSPLDPCDVHL--QAASY-SVQACSVLTGEM--FAPCSAFLSPVP 731
Query: 2672 YFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICT 2731
YF QC D C + + LC +LA Y C+ G+ V C L C A YS C
Sbjct: 732 YFEQCRRDAC--RCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCV 789
Query: 2732 RTCQGSCAALSGLTGC---------TTRCFEGCEC-DDRFLLSQG-VCIPVQDCGCTHNG 2780
C +C L+ C C EGC C D +L +Q +C+P C C G
Sbjct: 790 APCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQG 849
Query: 2781 RYLPVNSSLLTSDCSERCSCSS---SSGLTCQAAGCPPGRV 2818
P S + S C C S AA CP G+V
Sbjct: 850 VDYPPGDSDIPS--LGHCHCKDGVMSCDSRAPAAACPAGQV 888
Score = 161 bits (408), Expect = 8e-39
Identities = 154/588 (26%), Positives = 227/588 (38%), Gaps = 47/588 (7%)
Query: 2416 RCECGPGGHVTCQEGAACGPHE--ECRLEDGV----QACHATGCGR---CLANGGIHYIT 2466
R +C P +C G C +CR + Q + G R C A G H T
Sbjct: 102 RAKCAPSYLFSCFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVET 161
Query: 2467 LDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRL-------LVTVAGQVV 2519
DG Y L G SY L V +P + FSI + + L V Q +
Sbjct: 162 FDGLYYYLSGKGSYTL--VGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEI 219
Query: 2520 SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFR 2579
LA+ +VT G V LP +G R+ ++++ L +DG + + + +
Sbjct: 220 HLAK--EVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELL 277
Query: 2580 GRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAE 2639
G GLCGN N + DD V +G V F +W+ ++ G P CL +
Sbjct: 278 GWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQ 337
Query: 2640 ETAPYES-NEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYT 2698
+ E C L P PF C A +SP + C DLC GD A CR+LA Y
Sbjct: 338 NPGTMQGVYEQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYA 395
Query: 2699 AACQAAGVAVKPWRTD-SFCPLHCPAHSH-YSICTRTCQGSCAALSGLTGCTTRCFEGCE 2756
AC AG ++ WRT C +HC + Y+ C C SC + C +GC
Sbjct: 396 RACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCY 455
Query: 2757 CDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPG 2816
C + + G C+ +C C +G P S++ DC+ C+C+S C A CP
Sbjct: 456 CPNGLIFEDGGCVAPAECPCEFHGTLYP-PGSVVKEDCN-TCTCTSGK-WECSTAVCP-- 510
Query: 2817 RVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYR 2876
AE C ++ + TTFDG R + Y L+ T+
Sbjct: 511 ------AE----------CSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQN 554
Query: 2877 VVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDG 2936
+ ++V + VTLT V + +P + + R
Sbjct: 555 APCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSV 614
Query: 2937 SLLVRQKAGVQVWLGANG-KVAVIVSNDHAGKLCGACGNFDGDQTNDW 2983
L VR GV+V G ++ + V G CG F+G+ +D+
Sbjct: 615 FLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDF 662
Score = 115 bits (287), Expect = 9e-25
Identities = 111/421 (26%), Positives = 162/421 (38%), Gaps = 61/421 (14%)
Query: 729 GISVGDWRSPANCPLSCPANSRYELCGP-------ACPTSCNGAAAPSNCSGR-PCVEGC 780
G+ D R+PA +CPA + C + +C + S R PC+ GC
Sbjct: 870 GVMSCDSRAPA---AACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGC 926
Query: 781 VCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQS 840
C G + G AC C CT++G + PG +V + C C C + Q T S
Sbjct: 927 ACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSP--C-HTCVCQRGSFQCTLHPCAS 983
Query: 841 CPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL 900
TC GD HY +FDG FDF+G C LV S
Sbjct: 984 ----------------------TCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD---- 1017
Query: 901 PAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADG-- 958
+F V+VEN + S + + + + + V DD P D
Sbjct: 1018 VSFSVIVENVNCYSSGMICRKFISINVGNSLI---------VFDDDSGNPSPESFLDDKQ 1068
Query: 959 QVQVFRQGRDAVVR-TDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALR 1017
+V +R G +V +T+ +D V + + L GLCGNF+ +++
Sbjct: 1069 EVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTP 1128
Query: 1018 GGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRE 1077
+ N FG+SW P +P D L+ L ++ +K EC IL F
Sbjct: 1129 ENLELTNPQEFGSSWAAVECP--DTLDPRDMCVLNPL--REPFAKKECSILLSE--VFEI 1182
Query: 1078 CHSKLDPQGAVRDCVYDR--CLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLS 1135
CH +D +C+ D C G C +++ YA C G V WR+ LCP
Sbjct: 1183 CHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYD 1241
Query: 1136 C 1136
C
Sbjct: 1242 C 1242
Score = 98.6 bits (244), Expect = 8e-20
Identities = 82/297 (27%), Positives = 126/297 (42%), Gaps = 27/297 (9%)
Query: 455 CQVVGGKAGCVAESTA-VCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSV 513
C G C A C A GD HY TFDG +D +G C +V+ S+ +FSV
Sbjct: 967 CVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD----VSFSV 1022
Query: 514 EAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQS 573
+N + Y + R + +S+ G V D+ + P S + + V+
Sbjct: 1023 IVENVN------CYSSGMICRKF---ISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTW 1073
Query: 574 GPRAVVELVFGLV-VTYDWDCQLALSLPA--RFQDQVCGLCGNYNGDPADDFLTPDGALA 630
+ F +T WD + + + A ++Q Q+ GLCGN++ ++ TP+
Sbjct: 1074 RVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLEL 1133
Query: 631 PDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDT 690
+ EF SSW + C D C + + C +L L F +CH
Sbjct: 1134 TNPQEFGSSWAAVE----CPDTLDPR-DMCVLNPLREPFAKKECSIL--LSEVFEICHPV 1186
Query: 691 LDPRPFLEQCVYDL--CVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSC 745
+D F C+ D C GG+ C +SAYA C + G++V DWR+P CP C
Sbjct: 1187 VDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1242
Score = 92.4 bits (228), Expect = 6e-18
Identities = 117/502 (23%), Positives = 189/502 (37%), Gaps = 87/502 (17%)
Query: 2355 SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLH----DGRYYPLGEVFYPG 2410
S P+LS EG A + + TCVP+ + C+ +G+ + + +
Sbjct: 2025 SAPALSIVEGLAEALATTTEAN-----TSTTCVPIAEQDCVRHICLEGQLIRVNQSQHC- 2078
Query: 2411 PECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGR 2470
P+ CG G G C P EC AC RC + ++T DG
Sbjct: 2079 PQGAAPPRCGILGLAVRVGGDRCCPLWEC-------AC------RCSIFPDLSFVTFDGS 2125
Query: 2471 VYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRL-----------LVTVAGQVV 2519
L Y+L+Q DE ++ + + +L L + +A QV
Sbjct: 2126 HVALFKEAIYILSQ-----SPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVT 2180
Query: 2520 SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLM---SIPS 2576
++VTVD + V PV+ R+ G ++ T +++ + + L++ S S
Sbjct: 2181 IDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTS 2240
Query: 2577 PFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVET---FGAAWRAPGSSKGCGE------G 2627
+G GLCG +G+ ++D L +GS E F +W+ P S G+
Sbjct: 2241 KAQGH--GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDS 2298
Query: 2628 CGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDK 2687
C C CL + AC + P+ + C+ + ++Y +Q
Sbjct: 2299 CATTDCSPCL--RMVSNRTFSACHRFVPPE---SFCELWIRDTKYVQQP----------- 2342
Query: 2688 AFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTG- 2746
C +L Y A C V ++ WR +CP C + S Y C C+ G+ G
Sbjct: 2343 ---CVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGP 2398
Query: 2747 -----CTTRCFEGCECDDRFLLSQ---GVCIPVQDCGCTHN---GRYLPVNSSLLTSDCS 2795
C EGC C + +L + +CIP C CT + R L + S C
Sbjct: 2399 LDPEHCQV-LGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCC 2457
Query: 2796 ERCSCSSSSGLTCQAAGCPPGR 2817
+ C + + GCP R
Sbjct: 2458 QH-QCQAPDTIVPVDLGCPSPR 2478
Score = 91.3 bits (225), Expect = 1e-17
Identities = 115/456 (25%), Positives = 171/456 (37%), Gaps = 78/456 (17%)
Query: 419 GLAKAIGYATAADCGRTVLSPVEPSCEGMQCAAGQ-----------------RCQV---- 457
GLA+A+ T A+ T + E C C GQ RC +
Sbjct: 2034 GLAEALATTTEANTSTTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLA 2093
Query: 458 --VGGKAGC-VAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVE 514
VGG C + E C D + TFDG + Y + + S D+ L ++
Sbjct: 2094 VRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQ--SPDEMLTVHVLD 2151
Query: 515 AKNEHRGSRRVSYVGLVTVRA--YSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQ 572
K+ + G LV + +H V++ R V VD Q PVS R+
Sbjct: 2152 CKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRK-VTVDLQPVWPPVS--RYGFRIED 2208
Query: 573 SGPRAVVELVFGLVVTYDWDCQLALSLPARFQD-QVCGLCGNYNGDPADDFLTPDGAL-- 629
+G ++ + + + L + ++ Q GLCG +GD A+D DG++
Sbjct: 2209 TGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVG 2268
Query: 630 -APDAVEFASSWKLDDG------DYLCEDGCQN-NCPACTPGQAQHYEGDRLCGMLTKLD 681
A D F SW++ D C +C C R+ T
Sbjct: 2269 GAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCL----------RMVSNRT--- 2315
Query: 682 GPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANC 741
F+ CH + P F E + D V C L+ Y C + + + +WR C
Sbjct: 2316 --FSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCI-EWRRSDYC 2368
Query: 742 PLSCPANSRYELCGPAC--PTSCN----GAAAPSNCSGRPCVEGCVCLPGFV---ASGGA 792
P C ++S Y+ C AC P +C G P +C + EGCVC G +
Sbjct: 2369 PFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHC--QVLGEGCVCSEGTILHRRHSAL 2426
Query: 793 CVPASSCGCT-FQGLQLAPGQEVWADEL---CQRRC 824
C+P + C CT G+ A G E W L CQ +C
Sbjct: 2427 CIPEAKCACTDSMGVPRALG-ETWNSSLSGCCQHQC 2461
Score = 90.1 bits (222), Expect = 3e-17
Identities = 121/509 (23%), Positives = 184/509 (36%), Gaps = 82/509 (16%)
Query: 1216 CQEGGLVSCESSSCGPHEACQPSGGSLG---------CVAVGSSTCQAS--GDPHYTTFD 1264
C EG L+ S P A P G LG C + C+ S D + TFD
Sbjct: 2064 CLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFD 2123
Query: 1265 GRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQ 1324
G +Y+L+Q+ +H N+ N ++ + + +++
Sbjct: 2124 GSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDR 2183
Query: 1325 RQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQ 1384
KVTV+ + PV +I + H ++ +D ++ + + V
Sbjct: 2184 FNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMI-VEASKTSKA 2242
Query: 1385 QMCGLCGNYNGDPKDDFQKPNGSQAGNANE---FGNSWEEVVPDSPCLPPTPCPPGSEDC 1441
Q GLCG +GD +D +GS G A + F +SW+ VP S L D
Sbjct: 2243 QGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQ--VPSS--LTSVGQTRFRPDS 2298
Query: 1442 IPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSIL 1501
+ C P L ++S+ T S+CH+ V P+ + I D +
Sbjct: 2299 CATTDCSPCLR----------MVSNRT--FSACHRFVPPESFCELWIRDTKY----VQQP 2342
Query: 1502 CSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDG 1561
C + YV+ C +E WR +CP C +S Y+ C C P CQDG
Sbjct: 2343 CVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTAC-------EPPKTCQDG 2394
Query: 1562 ------------CAEGCQCDSGFLY---NGQACVPIQQCGCYHN-GV---YYEPEQTVLI 1602
EGC C G + + C+P +C C + GV E + L
Sbjct: 2395 ILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLS 2454
Query: 1603 DNCRQQCTCHAGKGMVCQEHSC---KPGQVCQPSGGILSCVTKDP-------------CH 1646
C+ Q C A +V + C +P + L TKDP C
Sbjct: 2455 GCCQHQ--CQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCE 2512
Query: 1647 GV--TCRPQETCKEQGGQGVCLPNYEATC 1673
G+ TCRP + C P+Y C
Sbjct: 2513 GLAPTCRPGHRLLTHFQEDSCCPSYSCEC 2541
Score = 84.7 bits (208), Expect = 1e-15
Identities = 105/415 (25%), Positives = 157/415 (37%), Gaps = 79/415 (19%)
Query: 2047 PASCGLGEVCGL-LPSGQHGCQPV--STAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAP 2103
P CG + GL + G C P+ C + D +VT DG Y+LS
Sbjct: 2084 PPRCG---ILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS 2140
Query: 2104 -----------CHGPPLGAEN---FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSAR- 2148
C LG N F + + N VT+ +N +T+ +
Sbjct: 2141 PDEMLTVHVLDCKSANLGHLNWPPFCLVMLN------MTHLAHQVTIDRFNRKVTVDLQP 2194
Query: 2149 -WPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRL----RVPA 2203
WP + F+++ H ++ + T S + + + S + + +
Sbjct: 2195 VWPPVSRYG-------FRIEDTGHMYM------ILTPSDIQIQWLHSSGLMIVEASKTSK 2241
Query: 2204 AYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECV-SKPCPSPCTPEQQESF 2262
A LCG+C D A+DL G VGGA+ + S PS T Q F
Sbjct: 2242 AQGHGLCGICDG---DAANDLTLKDGSV----VGGAEDPAPFLDSWQVPSSLTSVGQTRF 2294
Query: 2263 GGPDACGVISAT-------DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATY 2315
PD+C + + + CH VPP + + + D VQ C A+ Y
Sbjct: 2295 R-PDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVY 2349
Query: 2316 VAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSC--PVSCP----SLSAPEGCESAC 2369
VA C + EWRR D+CP C + S Y+ C +C P +C PE C+
Sbjct: 2350 VAMCHKFHVCI-EWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQ-VL 2407
Query: 2370 REGCVCDAGFVL---SGDTCVPVGQCGCLHD-GRYYPLGEVFYPGPE--CERRCE 2418
EGCVC G +L C+P +C C G LGE + C+ +C+
Sbjct: 2408 GEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQ 2462
Score = 78.6 bits (192), Expect = 9e-14
Identities = 119/493 (24%), Positives = 165/493 (33%), Gaps = 111/493 (22%)
Query: 816 ADELCQRRCTCNGATHQVTCRDKQSCPAGE---RCSVQNGLLG---------CYPDRFGT 863
A++ C R G +V Q CP G RC G+LG C P
Sbjct: 2055 AEQDCVRHICLEGQLIRVN--QSQHCPQGAAPPRC----GILGLAVRVGGDRCCPLWECA 2108
Query: 864 CQGS--GDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL----------------PAFRV 905
C+ S D +V+FDG Y+L S + + P V
Sbjct: 2109 CRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLV 2168
Query: 906 LVENEHRGSQTV--SYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVF 963
++ H Q + R V V+ + V V R G + D Y+ +D Q+Q
Sbjct: 2169 MLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRY--GFRIEDTGHMYMILTPSDIQIQWL 2226
Query: 964 RQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGG---G 1020
+V +K + LCG+C +GD A+DL L+ G G
Sbjct: 2227 HSSGLMIVEA---------------SKTSKAQGHGLCGIC---DGDAANDLTLKDGSVVG 2268
Query: 1021 QAANALAFGNSWQEE---TRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRE 1077
A + F +SWQ T G P C D ++ S F
Sbjct: 2269 GAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRT----------FSA 2318
Query: 1078 CHSKLDPQGA----VRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCP 1133
CH + P+ +RD Y + C AL Y A C + WR + CP
Sbjct: 2319 CHRFVPPESFCELWIRDTKYVQ--------QPCVALTVYVAMCHKFHVCIE-WRRSDYCP 2369
Query: 1134 LSCPPHSHYEACSYGC--PLSCGDLPVPGGCGSECH---EGCVCDEGFAL---SGESCLP 1185
C S Y+AC C P +C D + C EGCVC EG L C+P
Sbjct: 2370 FLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIP 2429
Query: 1186 LASCGCV-HQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGC 1244
A C C G G+T+ L C C + P LGC
Sbjct: 2430 EAKCACTDSMGVPRALGETW-------------NSSLSGCCQHQCQAPDTIVPV--DLGC 2474
Query: 1245 VAVGSSTCQASGD 1257
+ +C G+
Sbjct: 2475 PSPRPESCLRFGE 2487
Score = 63.9 bits (154), Expect = 2e-09
Identities = 113/434 (26%), Positives = 158/434 (36%), Gaps = 67/434 (15%)
Query: 1665 CLPNYEATCW--LWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQ 1722
C P +E C ++ D + +FDG Y+L+ + + LT + K+
Sbjct: 2101 CCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS-----PDEMLTVHVLDCKSA 2155
Query: 1723 NRGN---PAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQG 1779
N G+ P V ++ + L ++I + KV V + V PVS RI
Sbjct: 2156 NLGHLNWPPFCLV-MLNMTHLAHQVTIDRFN-RKVTVDLQPVWP--PVSRYGFRIEDTGH 2211
Query: 1780 ASKALLVADFGLQVSYDWNWR-VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTL--- 1835
L +D +Q + V+ + S G GLCG D + ND +G++
Sbjct: 2212 MYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLKDGSVVGG 2269
Query: 1836 ----APSIPIWG--GSWRAPGWDPLCWDECRGS-CPTCPEDRLEQYEGPGFCGPLASGTG 1888
AP + W S + G D C + C C L +
Sbjct: 2270 AEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPC----------------LRMVSN 2313
Query: 1889 GPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGC 1948
F+ CH VPPESF + + D C AL YVA C V IE WR C
Sbjct: 2314 RTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCIE-WRRSDYC 2368
Query: 1949 EITCPENSHYEVCGPPC--PASCPSP--APLTTPAVCEGPCVEGCQCDAGFVL---SADR 2001
C +S Y+ C C P +C PL P C+ EGC C G +L +
Sbjct: 2369 PFLCSSDSTYQACVTACEPPKTCQDGILGPL-DPEHCQ-VLGEGCVCSEGTILHRRHSAL 2426
Query: 2002 CVPLNNGCGCWANGTYHEAGSEFW---ADGTCSQWCRCGP-----GGGSLVCTPASC-GL 2052
C+P C C + A E W G C C+ G P SC
Sbjct: 2427 CIP-EAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRF 2485
Query: 2053 GEVCGLLPSGQHGC 2066
GEV LLP+ C
Sbjct: 2486 GEVALLLPTKDPCC 2499
Score = 32.7 bits (73), Expect = 5.6
Identities = 26/96 (27%), Positives = 33/96 (34%), Gaps = 17/96 (17%)
Query: 2721 CPAHSHYSICT-----------RTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCI 2769
CPA + C+ RTC+ LS C GC C L C
Sbjct: 883 CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLS--VSARGPCLSGCACPQGLLRHGDACF 940
Query: 2770 PVQDCGCTHNGR-YLPVNSSLLTSDCSERCSCSSSS 2804
++C CT G+ Y P + S C C C S
Sbjct: 941 LPEECPCTWKGKEYFP--GDQVMSPC-HTCVCQRGS 973
>gi|239749989 PREDICTED: otogelin isoform 2 [Homo sapiens]
Length = 2852
Score = 310 bits (793), Expect = 2e-83
Identities = 311/1219 (25%), Positives = 449/1219 (36%), Gaps = 194/1219 (15%)
Query: 831 HQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLL 890
H C ++ G RC + + P+R C+ G H +FDG + G +Y L
Sbjct: 49 HPAFCDCRRFNATGPRCQM---VYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTL 105
Query: 891 VGSCGQNAALPAFRVLVENEHR-GSQTVSYTRAVR---VEARGVKVAVRREYPG-QVLVD 945
VG +F + V N+ + GS + +RAV V + + +A + G +V +
Sbjct: 106 VGRHEPEGQ--SFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLP 163
Query: 946 DVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGN 1005
V+ Q G V +VR T+ +D + V K+ GLCGN
Sbjct: 164 HVMGSARLQQLAGYV---------IVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGN 214
Query: 1006 FNGDPADDLALRGGGQAANALAFGNSWQEETR---PGCGATEPGDCPKLDSLVAQQLQSK 1062
N DP DDL G + + F +SWQE+ PG + P L
Sbjct: 215 NNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVY 274
Query: 1063 NECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGAT 1122
+C L P PF CH+ + P C D C G C ALA YA AC AG
Sbjct: 275 EQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRP 332
Query: 1123 VHPWRSE-ELCPLSCPPHSH-YEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSG 1180
+ WR++ C + C + Y C CP SC C +GC C G
Sbjct: 333 LQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFED 392
Query: 1181 ESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGG 1240
C+ A C C GT +PPG C++ C C G C ++ C
Sbjct: 393 GGCVAPAECPCEFHGTLYPPGSVVKED--CNT-CTCTSGKW-ECSTAVC----------- 437
Query: 1241 SLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAW 1300
+ C +GD H+TTFDGRR+ F TC Y+LA++ + F V +N
Sbjct: 438 --------PAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSS----GTFTVTLQNAPC 485
Query: 1301 GNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKL--------PVVLANGQIRASQH 1352
G + VQ + L + R+ D+ L P +IR
Sbjct: 486 GLNQDGA----CVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS- 540
Query: 1353 GSDVVIETDFGLRVAYD---LVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQA 1409
+ + T+ G+RV YD L Y++ V + + GLCG +NG+ +DDF P G
Sbjct: 541 SVFLRVRTNVGVRVLYDREGLRLYLQ--VDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPE 598
Query: 1410 GNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTG 1469
FGNSW+ + SP + +P P C L+ + C +L+
Sbjct: 599 STPQLFGNSWKTLSACSPLVSGSPLDP----------CDVHLQAASYSVQACSVLTGEM- 647
Query: 1470 PLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCP 1529
+ C + P + C D C G LC+ + Y C+ G V+ C
Sbjct: 648 -FAPCSAFLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACA 704
Query: 1530 MECPPNSHYELCADTCSLGCSALSAPPQC---------QDGCAEGCQCDSGFLYNGQA-- 1578
+ C + Y C C C L++P C +D C EGC C + QA
Sbjct: 705 LSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADL 764
Query: 1579 CVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEH----SCKPGQV----- 1629
CVP QC C+ GV Y P + + C C G M C +C GQV
Sbjct: 765 CVPRNQCSCHFQGVDYPPGDSDI--PSLGHCHCKDGV-MSCDSRAPAAACPAGQVFVNCS 821
Query: 1630 -------------CQPSGGILSCVTKDPC------------HGVTC-------------- 1650
C+ LS + PC HG C
Sbjct: 822 DLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKE 881
Query: 1651 --------RPQETCKEQGGQGVC-LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLAT 1701
P TC Q G C L +TC +GD HY +FDG FDF G C L
Sbjct: 882 YFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHL-- 939
Query: 1702 TGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGV 1761
V + F+V +N N + + + +++ +G ++ + D+ G
Sbjct: 940 -----VKSTSDVSFSVIVENVNCYSSGMICRKFISI-NVGNSLIVFDDDSG--------- 984
Query: 1762 LTALPVSVADGRISVAQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCG 1818
P S D + V + F + + +D V V + G + GLCG
Sbjct: 985 -NPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCG 1043
Query: 1819 NMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSC---PTCPEDRLEQYE 1875
N D N+ P + +G SW A EC + C + L +
Sbjct: 1044 NFDLKTINEMRTPENLELTNPQEFGSSWAAV--------ECPDTLDPRDMCVLNPLREPF 1095
Query: 1876 GPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDRDILCKALASYVAACQ 1933
C L S F CH V F+ C+ D C GGD + C ++++Y C
Sbjct: 1096 AKKECSILLSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCC 1152
Query: 1934 AAGVVIEDWRAQVGCEITC 1952
GV + DWR C C
Sbjct: 1153 QHGVAV-DWRTPRLCPYDC 1170
Score = 296 bits (758), Expect = 2e-79
Identities = 305/1176 (25%), Positives = 449/1176 (38%), Gaps = 199/1176 (16%)
Query: 1667 PNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNR-G 1725
P ++ C WG H +FDG + G +Y L P + F++ N + G
Sbjct: 73 PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS-----FSIQVHNDPQCG 127
Query: 1726 NPAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALL 1785
+ + R V++ +G IH + V G+ LP + R+ Q A ++
Sbjct: 128 SSPYTCSRAVSLFFVGEQ-EIHLAK----EVTHGGMRVQLPHVMGSARLQ--QLAGYVIV 180
Query: 1786 VADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGS 1845
+++D V + + G GLCGN + +P +D V +G L + + S
Sbjct: 181 RHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHS 240
Query: 1846 WR--APGWDPLCWDECRGSCPTCPEDRLEQYEGP--GFCGPLASGTGGPFTTCHAHVPPE 1901
W+ AP P S P P L+Q G G + PF CHA+V P
Sbjct: 241 WQEQAPNQPP---GPTTSSLPRPP--CLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPL 295
Query: 1902 SFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV-GCEITCPENSH-YE 1959
F C D+C GD C+ALA Y AC AG ++ WR Q+ C + C E + Y
Sbjct: 296 PFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYN 355
Query: 1960 VCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHE 2019
C CPASC P + E CV+GC C G + CV C C +GT +
Sbjct: 356 ECIACCPASC---HPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE-CPCEFHGTLYP 411
Query: 2020 AGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGD 2079
GS D C+ C C G C+ A C AEC GD
Sbjct: 412 PGSVVKED--CNT-CTC--TSGKWECSTAVC--------------------PAECSVTGD 446
Query: 2080 PHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTLQI 2138
H+ T DG R+ F TC+Y+L+ + FTVT+ N G +Q + +SV++ +
Sbjct: 447 IHFTTFDGRRYTFPATCQYILA-----KSRSSGTFTVTLQNAPCGLNQDGACVQSVSVIL 501
Query: 2139 Y---NHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDS 2195
+ +TL+ L D + P+ D+ LS + V T G+ + +D +
Sbjct: 502 HQDPRRQVTLTQAGD-VLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREG 560
Query: 2196 F-VRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQGCGECV 2246
+ L+V + GLCG +N + DD + G P W+ A C V
Sbjct: 561 LRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA--CSPLV 618
Query: 2247 SKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPG 2306
S PC Q + AC V+ T APC + P YF+ C DAC+ G P
Sbjct: 619 SGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDACRC-GQP- 674
Query: 2307 GLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEGC- 2365
LC +A Y C+ G + R C L C A Y C C +C L++PE C
Sbjct: 675 CLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACG 734
Query: 2366 --------ESACREGCVC--DAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPG----- 2410
C EGC C D D CVP QC C G YP G+ P
Sbjct: 735 VDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCH 794
Query: 2411 -----PECERRCECG--PGGHV-----------------TCQE----------------- 2429
C+ R P G V TC++
Sbjct: 795 CKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGC 854
Query: 2430 ---------GAACGPHEECRL----------EDGVQACHATGCGR-------------CL 2457
G AC EEC + + CH C R C
Sbjct: 855 ACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCT 914
Query: 2458 ANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEK---NAAGDLQRLLVTV 2514
A G HY T DG +D G+C L + D FS+++E ++G + R
Sbjct: 915 AYGDRHYRTFDGLPFDFVGACKVHLVK----STSDVSFSVIVENVNCYSSGMICR----- 965
Query: 2515 AGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGR-------NMVLQTTKGLRLLFDGD 2567
+ +S+ G + V + P + E +V + + LL+D
Sbjct: 966 --KFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQR 1023
Query: 2568 AHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEG 2627
+ + ++G+L GLCGNF+ ++ P ++ + FG++W A C +
Sbjct: 1024 TTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAA----VECPDT 1079
Query: 2628 CGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDL--CAQKG 2685
P+ +C+ + + C L + F C V+ + ++ C+ D C+Q G
Sbjct: 1080 LDPR--DMCVLNPLREPFAKKECSILLSE--VFEICHPVVDVTWFYSNCLTDTCGCSQGG 1135
Query: 2686 DKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHC 2721
D C S++AY C GVAV WRT CP C
Sbjct: 1136 DCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1170
Score = 280 bits (716), Expect = 2e-74
Identities = 247/825 (29%), Positives = 336/825 (40%), Gaps = 105/825 (12%)
Query: 450 AAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLP 509
A G RCQ+V E ++CRA G H TFDG Y + G SYT+V +
Sbjct: 60 ATGPRCQMVYNAG---PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQ-- 114
Query: 510 AFSVEAKNE-------HRGSRRVS--YVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLP 560
+FS++ N+ + SR VS +VG + + +T G R +LP
Sbjct: 115 SFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHL---AKEVTHG--------GMRVQLP 163
Query: 561 VSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPAD 620
+ RL+ Q +V + +D + + + GLCGN N DP D
Sbjct: 164 HVMGSARLQ--QLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKD 221
Query: 621 DFLTPDGALAPDAVEFASSWKLDDGDY--------LCEDGCQNNCPACTPGQAQHYEGDR 672
D +T G L D VEF SW+ + L C P G + E
Sbjct: 222 DLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEA-- 279
Query: 673 LCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISV 732
L PF CH + P PF C DLC G+ + CR L+ YA+AC + G +
Sbjct: 280 ------LLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 333
Query: 733 GDWRSP-ANCPLSCPANS-RYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASG 790
WR+ C + C + Y C CP SC+ A+ + S CV+GC C G +
Sbjct: 334 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVD-SEIACVDGCYCPNGLIFED 392
Query: 791 GACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQ 850
G CV + C C F G PG V D C CTC + + CPA CSV
Sbjct: 393 GGCVAPAECPCEFHGTLYPPGSVVKED--C-NTCTCTSGKWECS---TAVCPA--ECSV- 443
Query: 851 NGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENE 910
+GD H+ +FDGRR+ F TC Y+L S F V ++N
Sbjct: 444 ----------------TGDIHFTTFDGRRYTFPATCQYILAKSRSSG----TFTVTLQNA 483
Query: 911 HRG-SQTVSYTRAVRVEA-RGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRD 968
G +Q + ++V V + + V G VL+ D + +P D ++ R
Sbjct: 484 PCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIP-PYTDDAFEIRRLSSV 542
Query: 969 AV-VRTDFGLTVTYDWNA-RVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANAL 1026
+ VRT+ G+ V YD R+ +V + E GLCG FNG+ DD G +
Sbjct: 543 FLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQ 602
Query: 1027 AFGNSWQEETRPGCGATEPGD-CPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQ 1085
FGNSW +T C G D + S C +L F C + L P
Sbjct: 603 LFGNSW--KTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEM--FAPCSAFLSPV 658
Query: 1086 GAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEAC 1145
C D C GQ LC LA YA C+ G V C LSC Y C
Sbjct: 659 PYFEQCRRDACRC-GQP-CLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPC 716
Query: 1146 SYGCPLSCGDLPVPGGCG---------SECHEGCVC--DEGFALSGESCLPLASCGCVHQ 1194
C +C DL P CG EC EGC C D + C+P C C Q
Sbjct: 717 VAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQ 776
Query: 1195 GTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSG 1239
G +PPG + P G CHC++ G++SC+S + P AC P+G
Sbjct: 777 GVDYPPGDSDIPSLG---HCHCKD-GVMSCDSRA--PAAAC-PAG 814
Score = 254 bits (649), Expect = 9e-67
Identities = 233/821 (28%), Positives = 317/821 (38%), Gaps = 90/821 (10%)
Query: 2040 GGSLVCTPASCGLGEVCGLLPSGQ--HGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCE 2097
GG V PA C P Q + P + C+AWG H T DG + G
Sbjct: 44 GGECV-HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGS 102
Query: 2098 YLLSAPCHGPPLGAENFTVTVANEHR-GSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD 2156
Y L H P ++F++ V N+ + GS + +R+V+L +++
Sbjct: 103 YTLVGR-HEPE--GQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQ---EIHLAKEVTHG 156
Query: 2157 GVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNY 2216
G+ V LP + S L+G V+V S +LA+DG S V +++ GLCGN
Sbjct: 157 GMRVQLPHVMGSARLQQLAGY-VIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNN 215
Query: 2217 NQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCT------PEQQESFGGPDACGV 2270
N DP DDL GK V E P P T P Q++ G GV
Sbjct: 216 NADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQ--GV 273
Query: 2271 ISATDGPLAP----CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQL 2326
+ L P CH V P + C D CQ G C A+A Y AC AG L
Sbjct: 274 YEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 333
Query: 2327 GEWRRP-DFCPLQCPAHSH-YELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGD 2384
WR C + C + Y C CP SC ++ E AC +GC C G +
Sbjct: 334 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDG 393
Query: 2385 TCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDG 2444
CV +C C G YP PG + C C G
Sbjct: 394 GCVAPAECPCEFHGTLYP------PGSVVKEDCNT-------------------CTCTSG 428
Query: 2445 VQACHATGC-GRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNA 2503
C C C G IH+ T DGR Y +C Y+LA+ F++ L+
Sbjct: 429 KWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAK----SRSSGTFTVTLQNAP 484
Query: 2504 AG---------DLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVL 2554
G + +L + V+L Q V + + +P ++ L
Sbjct: 485 CGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFL 544
Query: 2555 Q--TTKGLRLLFDGDA-HLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETF 2611
+ T G+R+L+D + L + + + GLCG FNGN DDF+ P G S+ + F
Sbjct: 545 RVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLF 604
Query: 2612 GAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSE 2671
G +W+ + G C V L + A Y S +AC L FA C A LSP
Sbjct: 605 GNSWKTLSACSPLVSGSPLDPCDVHL--QAASY-SVQACSVLTGEM--FAPCSAFLSPVP 659
Query: 2672 YFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICT 2731
YF QC D C + + LC +LA Y C+ G+ V C L C A YS C
Sbjct: 660 YFEQCRRDAC--RCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCV 717
Query: 2732 RTCQGSCAALSGLTGC---------TTRCFEGCEC-DDRFLLSQG-VCIPVQDCGCTHNG 2780
C +C L+ C C EGC C D +L +Q +C+P C C G
Sbjct: 718 APCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQG 777
Query: 2781 RYLPVNSSLLTSDCSERCSCSS---SSGLTCQAAGCPPGRV 2818
P S + S C C S AA CP G+V
Sbjct: 778 VDYPPGDSDIPS--LGHCHCKDGVMSCDSRAPAAACPAGQV 816
Score = 161 bits (408), Expect = 8e-39
Identities = 154/588 (26%), Positives = 227/588 (38%), Gaps = 47/588 (7%)
Query: 2416 RCECGPGGHVTCQEGAACGPHE--ECRLEDGV----QACHATGCGR---CLANGGIHYIT 2466
R +C P +C G C +CR + Q + G R C A G H T
Sbjct: 30 RAKCAPSYLFSCFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVET 89
Query: 2467 LDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRL-------LVTVAGQVV 2519
DG Y L G SY L V +P + FSI + + L V Q +
Sbjct: 90 FDGLYYYLSGKGSYTL--VGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEI 147
Query: 2520 SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFR 2579
LA+ +VT G V LP +G R+ ++++ L +DG + + + +
Sbjct: 148 HLAK--EVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELL 205
Query: 2580 GRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAE 2639
G GLCGN N + DD V +G V F +W+ ++ G P CL +
Sbjct: 206 GWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQ 265
Query: 2640 ETAPYES-NEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYT 2698
+ E C L P PF C A +SP + C DLC GD A CR+LA Y
Sbjct: 266 NPGTMQGVYEQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYA 323
Query: 2699 AACQAAGVAVKPWRTD-SFCPLHCPAHSH-YSICTRTCQGSCAALSGLTGCTTRCFEGCE 2756
AC AG ++ WRT C +HC + Y+ C C SC + C +GC
Sbjct: 324 RACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCY 383
Query: 2757 CDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPG 2816
C + + G C+ +C C +G P S++ DC+ C+C+S C A CP
Sbjct: 384 CPNGLIFEDGGCVAPAECPCEFHGTLYP-PGSVVKEDCN-TCTCTSGK-WECSTAVCP-- 438
Query: 2817 RVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYR 2876
AE C ++ + TTFDG R + Y L+ T+
Sbjct: 439 ------AE----------CSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQN 482
Query: 2877 VVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDG 2936
+ ++V + VTLT V + +P + + R
Sbjct: 483 APCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSV 542
Query: 2937 SLLVRQKAGVQVWLGANG-KVAVIVSNDHAGKLCGACGNFDGDQTNDW 2983
L VR GV+V G ++ + V G CG F+G+ +D+
Sbjct: 543 FLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDF 590
Score = 115 bits (287), Expect = 9e-25
Identities = 111/421 (26%), Positives = 162/421 (38%), Gaps = 61/421 (14%)
Query: 729 GISVGDWRSPANCPLSCPANSRYELCGP-------ACPTSCNGAAAPSNCSGR-PCVEGC 780
G+ D R+PA +CPA + C + +C + S R PC+ GC
Sbjct: 798 GVMSCDSRAPA---AACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGC 854
Query: 781 VCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQS 840
C G + G AC C CT++G + PG +V + C C C + Q T S
Sbjct: 855 ACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSP--C-HTCVCQRGSFQCTLHPCAS 911
Query: 841 CPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL 900
TC GD HY +FDG FDF+G C LV S
Sbjct: 912 ----------------------TCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD---- 945
Query: 901 PAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADG-- 958
+F V+VEN + S + + + + + V DD P D
Sbjct: 946 VSFSVIVENVNCYSSGMICRKFISINVGNSLI---------VFDDDSGNPSPESFLDDKQ 996
Query: 959 QVQVFRQGRDAVVR-TDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALR 1017
+V +R G +V +T+ +D V + + L GLCGNF+ +++
Sbjct: 997 EVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTP 1056
Query: 1018 GGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRE 1077
+ N FG+SW P +P D L+ L ++ +K EC IL F
Sbjct: 1057 ENLELTNPQEFGSSWAAVECP--DTLDPRDMCVLNPL--REPFAKKECSILLSE--VFEI 1110
Query: 1078 CHSKLDPQGAVRDCVYDR--CLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLS 1135
CH +D +C+ D C G C +++ YA C G V WR+ LCP
Sbjct: 1111 CHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYD 1169
Query: 1136 C 1136
C
Sbjct: 1170 C 1170
Score = 98.6 bits (244), Expect = 8e-20
Identities = 82/297 (27%), Positives = 126/297 (42%), Gaps = 27/297 (9%)
Query: 455 CQVVGGKAGCVAESTA-VCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSV 513
C G C A C A GD HY TFDG +D +G C +V+ S+ +FSV
Sbjct: 895 CVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD----VSFSV 950
Query: 514 EAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQS 573
+N + Y + R + +S+ G V D+ + P S + + V+
Sbjct: 951 IVENVN------CYSSGMICRKF---ISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTW 1001
Query: 574 GPRAVVELVFGLV-VTYDWDCQLALSLPA--RFQDQVCGLCGNYNGDPADDFLTPDGALA 630
+ F +T WD + + + A ++Q Q+ GLCGN++ ++ TP+
Sbjct: 1002 RVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLEL 1061
Query: 631 PDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDT 690
+ EF SSW + C D C + + C +L L F +CH
Sbjct: 1062 TNPQEFGSSWAAVE----CPDTLDPR-DMCVLNPLREPFAKKECSIL--LSEVFEICHPV 1114
Query: 691 LDPRPFLEQCVYDL--CVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSC 745
+D F C+ D C GG+ C +SAYA C + G++V DWR+P CP C
Sbjct: 1115 VDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1170
Score = 92.4 bits (228), Expect = 6e-18
Identities = 117/502 (23%), Positives = 189/502 (37%), Gaps = 87/502 (17%)
Query: 2355 SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLH----DGRYYPLGEVFYPG 2410
S P+LS EG A + + TCVP+ + C+ +G+ + + +
Sbjct: 1953 SAPALSIVEGLAEALATTTEAN-----TSTTCVPIAEQDCVRHICLEGQLIRVNQSQHC- 2006
Query: 2411 PECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGR 2470
P+ CG G G C P EC AC RC + ++T DG
Sbjct: 2007 PQGAAPPRCGILGLAVRVGGDRCCPLWEC-------AC------RCSIFPDLSFVTFDGS 2053
Query: 2471 VYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRL-----------LVTVAGQVV 2519
L Y+L+Q DE ++ + + +L L + +A QV
Sbjct: 2054 HVALFKEAIYILSQ-----SPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVT 2108
Query: 2520 SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLM---SIPS 2576
++VTVD + V PV+ R+ G ++ T +++ + + L++ S S
Sbjct: 2109 IDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTS 2168
Query: 2577 PFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVET---FGAAWRAPGSSKGCGE------G 2627
+G GLCG +G+ ++D L +GS E F +W+ P S G+
Sbjct: 2169 KAQGH--GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDS 2226
Query: 2628 CGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDK 2687
C C CL + AC + P+ + C+ + ++Y +Q
Sbjct: 2227 CATTDCSPCL--RMVSNRTFSACHRFVPPE---SFCELWIRDTKYVQQP----------- 2270
Query: 2688 AFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTG- 2746
C +L Y A C V ++ WR +CP C + S Y C C+ G+ G
Sbjct: 2271 ---CVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGP 2326
Query: 2747 -----CTTRCFEGCECDDRFLLSQ---GVCIPVQDCGCTHN---GRYLPVNSSLLTSDCS 2795
C EGC C + +L + +CIP C CT + R L + S C
Sbjct: 2327 LDPEHCQV-LGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCC 2385
Query: 2796 ERCSCSSSSGLTCQAAGCPPGR 2817
+ C + + GCP R
Sbjct: 2386 QH-QCQAPDTIVPVDLGCPSPR 2406
Score = 91.3 bits (225), Expect = 1e-17
Identities = 115/456 (25%), Positives = 171/456 (37%), Gaps = 78/456 (17%)
Query: 419 GLAKAIGYATAADCGRTVLSPVEPSCEGMQCAAGQ-----------------RCQV---- 457
GLA+A+ T A+ T + E C C GQ RC +
Sbjct: 1962 GLAEALATTTEANTSTTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLA 2021
Query: 458 --VGGKAGC-VAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVE 514
VGG C + E C D + TFDG + Y + + S D+ L ++
Sbjct: 2022 VRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQ--SPDEMLTVHVLD 2079
Query: 515 AKNEHRGSRRVSYVGLVTVRA--YSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQ 572
K+ + G LV + +H V++ R V VD Q PVS R+
Sbjct: 2080 CKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRK-VTVDLQPVWPPVS--RYGFRIED 2136
Query: 573 SGPRAVVELVFGLVVTYDWDCQLALSLPARFQD-QVCGLCGNYNGDPADDFLTPDGAL-- 629
+G ++ + + + L + ++ Q GLCG +GD A+D DG++
Sbjct: 2137 TGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVG 2196
Query: 630 -APDAVEFASSWKLDDG------DYLCEDGCQN-NCPACTPGQAQHYEGDRLCGMLTKLD 681
A D F SW++ D C +C C R+ T
Sbjct: 2197 GAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCL----------RMVSNRT--- 2243
Query: 682 GPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANC 741
F+ CH + P F E + D V C L+ Y C + + + +WR C
Sbjct: 2244 --FSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCI-EWRRSDYC 2296
Query: 742 PLSCPANSRYELCGPAC--PTSCN----GAAAPSNCSGRPCVEGCVCLPGFV---ASGGA 792
P C ++S Y+ C AC P +C G P +C + EGCVC G +
Sbjct: 2297 PFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHC--QVLGEGCVCSEGTILHRRHSAL 2354
Query: 793 CVPASSCGCT-FQGLQLAPGQEVWADEL---CQRRC 824
C+P + C CT G+ A G E W L CQ +C
Sbjct: 2355 CIPEAKCACTDSMGVPRALG-ETWNSSLSGCCQHQC 2389
Score = 90.1 bits (222), Expect = 3e-17
Identities = 121/509 (23%), Positives = 184/509 (36%), Gaps = 82/509 (16%)
Query: 1216 CQEGGLVSCESSSCGPHEACQPSGGSLG---------CVAVGSSTCQAS--GDPHYTTFD 1264
C EG L+ S P A P G LG C + C+ S D + TFD
Sbjct: 1992 CLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFD 2051
Query: 1265 GRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQ 1324
G +Y+L+Q+ +H N+ N ++ + + +++
Sbjct: 2052 GSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDR 2111
Query: 1325 RQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQ 1384
KVTV+ + PV +I + H ++ +D ++ + + V
Sbjct: 2112 FNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMI-VEASKTSKA 2170
Query: 1385 QMCGLCGNYNGDPKDDFQKPNGSQAGNANE---FGNSWEEVVPDSPCLPPTPCPPGSEDC 1441
Q GLCG +GD +D +GS G A + F +SW+ VP S L D
Sbjct: 2171 QGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQ--VPSS--LTSVGQTRFRPDS 2226
Query: 1442 IPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSIL 1501
+ C P L ++S+ T S+CH+ V P+ + I D +
Sbjct: 2227 CATTDCSPCLR----------MVSNRT--FSACHRFVPPESFCELWIRDTKY----VQQP 2270
Query: 1502 CSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDG 1561
C + YV+ C +E WR +CP C +S Y+ C C P CQDG
Sbjct: 2271 CVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTAC-------EPPKTCQDG 2322
Query: 1562 ------------CAEGCQCDSGFLY---NGQACVPIQQCGCYHN-GV---YYEPEQTVLI 1602
EGC C G + + C+P +C C + GV E + L
Sbjct: 2323 ILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLS 2382
Query: 1603 DNCRQQCTCHAGKGMVCQEHSC---KPGQVCQPSGGILSCVTKDP-------------CH 1646
C+ Q C A +V + C +P + L TKDP C
Sbjct: 2383 GCCQHQ--CQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCE 2440
Query: 1647 GV--TCRPQETCKEQGGQGVCLPNYEATC 1673
G+ TCRP + C P+Y C
Sbjct: 2441 GLAPTCRPGHRLLTHFQEDSCCPSYSCEC 2469
Score = 84.7 bits (208), Expect = 1e-15
Identities = 105/415 (25%), Positives = 157/415 (37%), Gaps = 79/415 (19%)
Query: 2047 PASCGLGEVCGL-LPSGQHGCQPV--STAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAP 2103
P CG + GL + G C P+ C + D +VT DG Y+LS
Sbjct: 2012 PPRCG---ILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS 2068
Query: 2104 -----------CHGPPLGAEN---FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSAR- 2148
C LG N F + + N VT+ +N +T+ +
Sbjct: 2069 PDEMLTVHVLDCKSANLGHLNWPPFCLVMLN------MTHLAHQVTIDRFNRKVTVDLQP 2122
Query: 2149 -WPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRL----RVPA 2203
WP + F+++ H ++ + T S + + + S + + +
Sbjct: 2123 VWPPVSRYG-------FRIEDTGHMYM------ILTPSDIQIQWLHSSGLMIVEASKTSK 2169
Query: 2204 AYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECV-SKPCPSPCTPEQQESF 2262
A LCG+C D A+DL G VGGA+ + S PS T Q F
Sbjct: 2170 AQGHGLCGICDG---DAANDLTLKDGSV----VGGAEDPAPFLDSWQVPSSLTSVGQTRF 2222
Query: 2263 GGPDACGVISAT-------DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATY 2315
PD+C + + + CH VPP + + + D VQ C A+ Y
Sbjct: 2223 R-PDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVY 2277
Query: 2316 VAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSC--PVSCP----SLSAPEGCESAC 2369
VA C + EWRR D+CP C + S Y+ C +C P +C PE C+
Sbjct: 2278 VAMCHKFHVCI-EWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQ-VL 2335
Query: 2370 REGCVCDAGFVL---SGDTCVPVGQCGCLHD-GRYYPLGEVFYPGPE--CERRCE 2418
EGCVC G +L C+P +C C G LGE + C+ +C+
Sbjct: 2336 GEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQ 2390
Score = 78.6 bits (192), Expect = 9e-14
Identities = 119/493 (24%), Positives = 165/493 (33%), Gaps = 111/493 (22%)
Query: 816 ADELCQRRCTCNGATHQVTCRDKQSCPAGE---RCSVQNGLLG---------CYPDRFGT 863
A++ C R G +V Q CP G RC G+LG C P
Sbjct: 1983 AEQDCVRHICLEGQLIRVN--QSQHCPQGAAPPRC----GILGLAVRVGGDRCCPLWECA 2036
Query: 864 CQGS--GDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL----------------PAFRV 905
C+ S D +V+FDG Y+L S + + P V
Sbjct: 2037 CRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLV 2096
Query: 906 LVENEHRGSQTV--SYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVF 963
++ H Q + R V V+ + V V R G + D Y+ +D Q+Q
Sbjct: 2097 MLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRY--GFRIEDTGHMYMILTPSDIQIQWL 2154
Query: 964 RQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGG---G 1020
+V +K + LCG+C +GD A+DL L+ G G
Sbjct: 2155 HSSGLMIVEA---------------SKTSKAQGHGLCGIC---DGDAANDLTLKDGSVVG 2196
Query: 1021 QAANALAFGNSWQEE---TRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRE 1077
A + F +SWQ T G P C D ++ S F
Sbjct: 2197 GAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRT----------FSA 2246
Query: 1078 CHSKLDPQGA----VRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCP 1133
CH + P+ +RD Y + C AL Y A C + WR + CP
Sbjct: 2247 CHRFVPPESFCELWIRDTKYVQ--------QPCVALTVYVAMCHKFHVCIE-WRRSDYCP 2297
Query: 1134 LSCPPHSHYEACSYGC--PLSCGDLPVPGGCGSECH---EGCVCDEGFAL---SGESCLP 1185
C S Y+AC C P +C D + C EGCVC EG L C+P
Sbjct: 2298 FLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIP 2357
Query: 1186 LASCGCV-HQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGC 1244
A C C G G+T+ L C C + P LGC
Sbjct: 2358 EAKCACTDSMGVPRALGETW-------------NSSLSGCCQHQCQAPDTIVPV--DLGC 2402
Query: 1245 VAVGSSTCQASGD 1257
+ +C G+
Sbjct: 2403 PSPRPESCLRFGE 2415
Score = 63.9 bits (154), Expect = 2e-09
Identities = 113/434 (26%), Positives = 158/434 (36%), Gaps = 67/434 (15%)
Query: 1665 CLPNYEATCW--LWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQ 1722
C P +E C ++ D + +FDG Y+L+ + + LT + K+
Sbjct: 2029 CCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS-----PDEMLTVHVLDCKSA 2083
Query: 1723 NRGN---PAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQG 1779
N G+ P V ++ + L ++I + KV V + V PVS RI
Sbjct: 2084 NLGHLNWPPFCLV-MLNMTHLAHQVTIDRFN-RKVTVDLQPVWP--PVSRYGFRIEDTGH 2139
Query: 1780 ASKALLVADFGLQVSYDWNWR-VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTL--- 1835
L +D +Q + V+ + S G GLCG D + ND +G++
Sbjct: 2140 MYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLKDGSVVGG 2197
Query: 1836 ----APSIPIWG--GSWRAPGWDPLCWDECRGS-CPTCPEDRLEQYEGPGFCGPLASGTG 1888
AP + W S + G D C + C C L +
Sbjct: 2198 AEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPC----------------LRMVSN 2241
Query: 1889 GPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGC 1948
F+ CH VPPESF + + D C AL YVA C V IE WR C
Sbjct: 2242 RTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCIE-WRRSDYC 2296
Query: 1949 EITCPENSHYEVCGPPC--PASCPSP--APLTTPAVCEGPCVEGCQCDAGFVL---SADR 2001
C +S Y+ C C P +C PL P C+ EGC C G +L +
Sbjct: 2297 PFLCSSDSTYQACVTACEPPKTCQDGILGPL-DPEHCQ-VLGEGCVCSEGTILHRRHSAL 2354
Query: 2002 CVPLNNGCGCWANGTYHEAGSEFW---ADGTCSQWCRCGP-----GGGSLVCTPASC-GL 2052
C+P C C + A E W G C C+ G P SC
Sbjct: 2355 CIP-EAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRF 2413
Query: 2053 GEVCGLLPSGQHGC 2066
GEV LLP+ C
Sbjct: 2414 GEVALLLPTKDPCC 2427
Score = 32.7 bits (73), Expect = 5.6
Identities = 26/96 (27%), Positives = 33/96 (34%), Gaps = 17/96 (17%)
Query: 2721 CPAHSHYSICT-----------RTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCI 2769
CPA + C+ RTC+ LS C GC C L C
Sbjct: 811 CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLS--VSARGPCLSGCACPQGLLRHGDACF 868
Query: 2770 PVQDCGCTHNGR-YLPVNSSLLTSDCSERCSCSSSS 2804
++C CT G+ Y P + S C C C S
Sbjct: 869 LPEECPCTWKGKEYFP--GDQVMSPC-HTCVCQRGS 901
>gi|239749987 PREDICTED: otogelin isoform 1 [Homo sapiens]
Length = 2924
Score = 310 bits (793), Expect = 2e-83
Identities = 311/1219 (25%), Positives = 449/1219 (36%), Gaps = 194/1219 (15%)
Query: 831 HQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLL 890
H C ++ G RC + + P+R C+ G H +FDG + G +Y L
Sbjct: 121 HPAFCDCRRFNATGPRCQM---VYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTL 177
Query: 891 VGSCGQNAALPAFRVLVENEHR-GSQTVSYTRAVR---VEARGVKVAVRREYPG-QVLVD 945
VG +F + V N+ + GS + +RAV V + + +A + G +V +
Sbjct: 178 VGRHEPEGQ--SFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLP 235
Query: 946 DVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGN 1005
V+ Q G V +VR T+ +D + V K+ GLCGN
Sbjct: 236 HVMGSARLQQLAGYV---------IVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGN 286
Query: 1006 FNGDPADDLALRGGGQAANALAFGNSWQEETR---PGCGATEPGDCPKLDSLVAQQLQSK 1062
N DP DDL G + + F +SWQE+ PG + P L
Sbjct: 287 NNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVY 346
Query: 1063 NECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGAT 1122
+C L P PF CH+ + P C D C G C ALA YA AC AG
Sbjct: 347 EQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRP 404
Query: 1123 VHPWRSE-ELCPLSCPPHSH-YEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSG 1180
+ WR++ C + C + Y C CP SC C +GC C G
Sbjct: 405 LQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFED 464
Query: 1181 ESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGG 1240
C+ A C C GT +PPG C++ C C G C ++ C
Sbjct: 465 GGCVAPAECPCEFHGTLYPPGSVVKED--CNT-CTCTSGKW-ECSTAVC----------- 509
Query: 1241 SLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAW 1300
+ C +GD H+TTFDGRR+ F TC Y+LA++ + F V +N
Sbjct: 510 --------PAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSS----GTFTVTLQNAPC 557
Query: 1301 GNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKL--------PVVLANGQIRASQH 1352
G + VQ + L + R+ D+ L P +IR
Sbjct: 558 GLNQDGA----CVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS- 612
Query: 1353 GSDVVIETDFGLRVAYD---LVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQA 1409
+ + T+ G+RV YD L Y++ V + + GLCG +NG+ +DDF P G
Sbjct: 613 SVFLRVRTNVGVRVLYDREGLRLYLQ--VDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPE 670
Query: 1410 GNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTG 1469
FGNSW+ + SP + +P P C L+ + C +L+
Sbjct: 671 STPQLFGNSWKTLSACSPLVSGSPLDP----------CDVHLQAASYSVQACSVLTGEM- 719
Query: 1470 PLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCP 1529
+ C + P + C D C G LC+ + Y C+ G V+ C
Sbjct: 720 -FAPCSAFLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACA 776
Query: 1530 MECPPNSHYELCADTCSLGCSALSAPPQC---------QDGCAEGCQCDSGFLYNGQA-- 1578
+ C + Y C C C L++P C +D C EGC C + QA
Sbjct: 777 LSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADL 836
Query: 1579 CVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEH----SCKPGQV----- 1629
CVP QC C+ GV Y P + + C C G M C +C GQV
Sbjct: 837 CVPRNQCSCHFQGVDYPPGDSDI--PSLGHCHCKDGV-MSCDSRAPAAACPAGQVFVNCS 893
Query: 1630 -------------CQPSGGILSCVTKDPC------------HGVTC-------------- 1650
C+ LS + PC HG C
Sbjct: 894 DLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKE 953
Query: 1651 --------RPQETCKEQGGQGVC-LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLAT 1701
P TC Q G C L +TC +GD HY +FDG FDF G C L
Sbjct: 954 YFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHL-- 1011
Query: 1702 TGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGV 1761
V + F+V +N N + + + +++ +G ++ + D+ G
Sbjct: 1012 -----VKSTSDVSFSVIVENVNCYSSGMICRKFISI-NVGNSLIVFDDDSG--------- 1056
Query: 1762 LTALPVSVADGRISVAQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCG 1818
P S D + V + F + + +D V V + G + GLCG
Sbjct: 1057 -NPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCG 1115
Query: 1819 NMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSC---PTCPEDRLEQYE 1875
N D N+ P + +G SW A EC + C + L +
Sbjct: 1116 NFDLKTINEMRTPENLELTNPQEFGSSWAAV--------ECPDTLDPRDMCVLNPLREPF 1167
Query: 1876 GPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDRDILCKALASYVAACQ 1933
C L S F CH V F+ C+ D C GGD + C ++++Y C
Sbjct: 1168 AKKECSILLSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCC 1224
Query: 1934 AAGVVIEDWRAQVGCEITC 1952
GV + DWR C C
Sbjct: 1225 QHGVAV-DWRTPRLCPYDC 1242
Score = 296 bits (758), Expect = 2e-79
Identities = 305/1176 (25%), Positives = 449/1176 (38%), Gaps = 199/1176 (16%)
Query: 1667 PNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNR-G 1725
P ++ C WG H +FDG + G +Y L P + F++ N + G
Sbjct: 145 PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS-----FSIQVHNDPQCG 199
Query: 1726 NPAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALL 1785
+ + R V++ +G IH + V G+ LP + R+ Q A ++
Sbjct: 200 SSPYTCSRAVSLFFVGEQ-EIHLAK----EVTHGGMRVQLPHVMGSARLQ--QLAGYVIV 252
Query: 1786 VADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGS 1845
+++D V + + G GLCGN + +P +D V +G L + + S
Sbjct: 253 RHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHS 312
Query: 1846 WR--APGWDPLCWDECRGSCPTCPEDRLEQYEGP--GFCGPLASGTGGPFTTCHAHVPPE 1901
W+ AP P S P P L+Q G G + PF CHA+V P
Sbjct: 313 WQEQAPNQPP---GPTTSSLPRPP--CLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPL 367
Query: 1902 SFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV-GCEITCPENSH-YE 1959
F C D+C GD C+ALA Y AC AG ++ WR Q+ C + C E + Y
Sbjct: 368 PFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYN 427
Query: 1960 VCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHE 2019
C CPASC P + E CV+GC C G + CV C C +GT +
Sbjct: 428 ECIACCPASC---HPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE-CPCEFHGTLYP 483
Query: 2020 AGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGD 2079
GS D C+ C C G C+ A C AEC GD
Sbjct: 484 PGSVVKED--CNT-CTC--TSGKWECSTAVC--------------------PAECSVTGD 518
Query: 2080 PHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTLQI 2138
H+ T DG R+ F TC+Y+L+ + FTVT+ N G +Q + +SV++ +
Sbjct: 519 IHFTTFDGRRYTFPATCQYILA-----KSRSSGTFTVTLQNAPCGLNQDGACVQSVSVIL 573
Query: 2139 Y---NHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDS 2195
+ +TL+ L D + P+ D+ LS + V T G+ + +D +
Sbjct: 574 HQDPRRQVTLTQAGD-VLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREG 632
Query: 2196 F-VRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQGCGECV 2246
+ L+V + GLCG +N + DD + G P W+ A C V
Sbjct: 633 LRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA--CSPLV 690
Query: 2247 SKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPG 2306
S PC Q + AC V+ T APC + P YF+ C DAC+ G P
Sbjct: 691 SGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDACRC-GQP- 746
Query: 2307 GLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEGC- 2365
LC +A Y C+ G + R C L C A Y C C +C L++PE C
Sbjct: 747 CLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACG 806
Query: 2366 --------ESACREGCVC--DAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPG----- 2410
C EGC C D D CVP QC C G YP G+ P
Sbjct: 807 VDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCH 866
Query: 2411 -----PECERRCECG--PGGHV-----------------TCQE----------------- 2429
C+ R P G V TC++
Sbjct: 867 CKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGC 926
Query: 2430 ---------GAACGPHEECRL----------EDGVQACHATGCGR-------------CL 2457
G AC EEC + + CH C R C
Sbjct: 927 ACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCT 986
Query: 2458 ANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEK---NAAGDLQRLLVTV 2514
A G HY T DG +D G+C L + D FS+++E ++G + R
Sbjct: 987 AYGDRHYRTFDGLPFDFVGACKVHLVK----STSDVSFSVIVENVNCYSSGMICR----- 1037
Query: 2515 AGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGR-------NMVLQTTKGLRLLFDGD 2567
+ +S+ G + V + P + E +V + + LL+D
Sbjct: 1038 --KFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQR 1095
Query: 2568 AHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEG 2627
+ + ++G+L GLCGNF+ ++ P ++ + FG++W A C +
Sbjct: 1096 TTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAA----VECPDT 1151
Query: 2628 CGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDL--CAQKG 2685
P+ +C+ + + C L + F C V+ + ++ C+ D C+Q G
Sbjct: 1152 LDPR--DMCVLNPLREPFAKKECSILLSE--VFEICHPVVDVTWFYSNCLTDTCGCSQGG 1207
Query: 2686 DKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHC 2721
D C S++AY C GVAV WRT CP C
Sbjct: 1208 DCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1242
Score = 280 bits (716), Expect = 2e-74
Identities = 247/825 (29%), Positives = 336/825 (40%), Gaps = 105/825 (12%)
Query: 450 AAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLP 509
A G RCQ+V E ++CRA G H TFDG Y + G SYT+V +
Sbjct: 132 ATGPRCQMVYNAG---PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQ-- 186
Query: 510 AFSVEAKNE-------HRGSRRVS--YVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLP 560
+FS++ N+ + SR VS +VG + + +T G R +LP
Sbjct: 187 SFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHL---AKEVTHG--------GMRVQLP 235
Query: 561 VSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPAD 620
+ RL+ Q +V + +D + + + GLCGN N DP D
Sbjct: 236 HVMGSARLQ--QLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKD 293
Query: 621 DFLTPDGALAPDAVEFASSWKLDDGDY--------LCEDGCQNNCPACTPGQAQHYEGDR 672
D +T G L D VEF SW+ + L C P G + E
Sbjct: 294 DLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEA-- 351
Query: 673 LCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISV 732
L PF CH + P PF C DLC G+ + CR L+ YA+AC + G +
Sbjct: 352 ------LLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 405
Query: 733 GDWRSP-ANCPLSCPANS-RYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASG 790
WR+ C + C + Y C CP SC+ A+ + S CV+GC C G +
Sbjct: 406 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVD-SEIACVDGCYCPNGLIFED 464
Query: 791 GACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQ 850
G CV + C C F G PG V D C CTC + + CPA CSV
Sbjct: 465 GGCVAPAECPCEFHGTLYPPGSVVKED--C-NTCTCTSGKWECS---TAVCPA--ECSV- 515
Query: 851 NGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENE 910
+GD H+ +FDGRR+ F TC Y+L S F V ++N
Sbjct: 516 ----------------TGDIHFTTFDGRRYTFPATCQYILAKSRSSG----TFTVTLQNA 555
Query: 911 HRG-SQTVSYTRAVRVEA-RGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRD 968
G +Q + ++V V + + V G VL+ D + +P D ++ R
Sbjct: 556 PCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIP-PYTDDAFEIRRLSSV 614
Query: 969 AV-VRTDFGLTVTYDWNA-RVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANAL 1026
+ VRT+ G+ V YD R+ +V + E GLCG FNG+ DD G +
Sbjct: 615 FLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQ 674
Query: 1027 AFGNSWQEETRPGCGATEPGD-CPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQ 1085
FGNSW +T C G D + S C +L F C + L P
Sbjct: 675 LFGNSW--KTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEM--FAPCSAFLSPV 730
Query: 1086 GAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEAC 1145
C D C GQ LC LA YA C+ G V C LSC Y C
Sbjct: 731 PYFEQCRRDACRC-GQP-CLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPC 788
Query: 1146 SYGCPLSCGDLPVPGGCG---------SECHEGCVC--DEGFALSGESCLPLASCGCVHQ 1194
C +C DL P CG EC EGC C D + C+P C C Q
Sbjct: 789 VAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQ 848
Query: 1195 GTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSG 1239
G +PPG + P G CHC++ G++SC+S + P AC P+G
Sbjct: 849 GVDYPPGDSDIPSLG---HCHCKD-GVMSCDSRA--PAAAC-PAG 886
Score = 254 bits (649), Expect = 9e-67
Identities = 233/821 (28%), Positives = 317/821 (38%), Gaps = 90/821 (10%)
Query: 2040 GGSLVCTPASCGLGEVCGLLPSGQ--HGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCE 2097
GG V PA C P Q + P + C+AWG H T DG + G
Sbjct: 116 GGECV-HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGS 174
Query: 2098 YLLSAPCHGPPLGAENFTVTVANEHR-GSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD 2156
Y L H P ++F++ V N+ + GS + +R+V+L +++
Sbjct: 175 YTLVGR-HEPE--GQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQ---EIHLAKEVTHG 228
Query: 2157 GVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNY 2216
G+ V LP + S L+G V+V S +LA+DG S V +++ GLCGN
Sbjct: 229 GMRVQLPHVMGSARLQQLAGY-VIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNN 287
Query: 2217 NQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCT------PEQQESFGGPDACGV 2270
N DP DDL GK V E P P T P Q++ G GV
Sbjct: 288 NADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQ--GV 345
Query: 2271 ISATDGPLAP----CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQL 2326
+ L P CH V P + C D CQ G C A+A Y AC AG L
Sbjct: 346 YEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 405
Query: 2327 GEWRRP-DFCPLQCPAHSH-YELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGD 2384
WR C + C + Y C CP SC ++ E AC +GC C G +
Sbjct: 406 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDG 465
Query: 2385 TCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDG 2444
CV +C C G YP PG + C C G
Sbjct: 466 GCVAPAECPCEFHGTLYP------PGSVVKEDCNT-------------------CTCTSG 500
Query: 2445 VQACHATGC-GRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNA 2503
C C C G IH+ T DGR Y +C Y+LA+ F++ L+
Sbjct: 501 KWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAK----SRSSGTFTVTLQNAP 556
Query: 2504 AG---------DLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVL 2554
G + +L + V+L Q V + + +P ++ L
Sbjct: 557 CGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFL 616
Query: 2555 Q--TTKGLRLLFDGDA-HLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETF 2611
+ T G+R+L+D + L + + + GLCG FNGN DDF+ P G S+ + F
Sbjct: 617 RVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLF 676
Query: 2612 GAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSE 2671
G +W+ + G C V L + A Y S +AC L FA C A LSP
Sbjct: 677 GNSWKTLSACSPLVSGSPLDPCDVHL--QAASY-SVQACSVLTGEM--FAPCSAFLSPVP 731
Query: 2672 YFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICT 2731
YF QC D C + + LC +LA Y C+ G+ V C L C A YS C
Sbjct: 732 YFEQCRRDAC--RCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCV 789
Query: 2732 RTCQGSCAALSGLTGC---------TTRCFEGCEC-DDRFLLSQG-VCIPVQDCGCTHNG 2780
C +C L+ C C EGC C D +L +Q +C+P C C G
Sbjct: 790 APCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQG 849
Query: 2781 RYLPVNSSLLTSDCSERCSCSS---SSGLTCQAAGCPPGRV 2818
P S + S C C S AA CP G+V
Sbjct: 850 VDYPPGDSDIPS--LGHCHCKDGVMSCDSRAPAAACPAGQV 888
Score = 161 bits (408), Expect = 8e-39
Identities = 154/588 (26%), Positives = 227/588 (38%), Gaps = 47/588 (7%)
Query: 2416 RCECGPGGHVTCQEGAACGPHE--ECRLEDGV----QACHATGCGR---CLANGGIHYIT 2466
R +C P +C G C +CR + Q + G R C A G H T
Sbjct: 102 RAKCAPSYLFSCFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVET 161
Query: 2467 LDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRL-------LVTVAGQVV 2519
DG Y L G SY L V +P + FSI + + L V Q +
Sbjct: 162 FDGLYYYLSGKGSYTL--VGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEI 219
Query: 2520 SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFR 2579
LA+ +VT G V LP +G R+ ++++ L +DG + + + +
Sbjct: 220 HLAK--EVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELL 277
Query: 2580 GRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAE 2639
G GLCGN N + DD V +G V F +W+ ++ G P CL +
Sbjct: 278 GWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQ 337
Query: 2640 ETAPYES-NEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYT 2698
+ E C L P PF C A +SP + C DLC GD A CR+LA Y
Sbjct: 338 NPGTMQGVYEQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYA 395
Query: 2699 AACQAAGVAVKPWRTD-SFCPLHCPAHSH-YSICTRTCQGSCAALSGLTGCTTRCFEGCE 2756
AC AG ++ WRT C +HC + Y+ C C SC + C +GC
Sbjct: 396 RACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCY 455
Query: 2757 CDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPG 2816
C + + G C+ +C C +G P S++ DC+ C+C+S C A CP
Sbjct: 456 CPNGLIFEDGGCVAPAECPCEFHGTLYP-PGSVVKEDCN-TCTCTSGK-WECSTAVCP-- 510
Query: 2817 RVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYR 2876
AE C ++ + TTFDG R + Y L+ T+
Sbjct: 511 ------AE----------CSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQN 554
Query: 2877 VVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDG 2936
+ ++V + VTLT V + +P + + R
Sbjct: 555 APCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSV 614
Query: 2937 SLLVRQKAGVQVWLGANG-KVAVIVSNDHAGKLCGACGNFDGDQTNDW 2983
L VR GV+V G ++ + V G CG F+G+ +D+
Sbjct: 615 FLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDF 662
Score = 115 bits (287), Expect = 9e-25
Identities = 111/421 (26%), Positives = 162/421 (38%), Gaps = 61/421 (14%)
Query: 729 GISVGDWRSPANCPLSCPANSRYELCGP-------ACPTSCNGAAAPSNCSGR-PCVEGC 780
G+ D R+PA +CPA + C + +C + S R PC+ GC
Sbjct: 870 GVMSCDSRAPA---AACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGC 926
Query: 781 VCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQS 840
C G + G AC C CT++G + PG +V + C C C + Q T S
Sbjct: 927 ACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSP--C-HTCVCQRGSFQCTLHPCAS 983
Query: 841 CPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL 900
TC GD HY +FDG FDF+G C LV S
Sbjct: 984 ----------------------TCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD---- 1017
Query: 901 PAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADG-- 958
+F V+VEN + S + + + + + V DD P D
Sbjct: 1018 VSFSVIVENVNCYSSGMICRKFISINVGNSLI---------VFDDDSGNPSPESFLDDKQ 1068
Query: 959 QVQVFRQGRDAVVR-TDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALR 1017
+V +R G +V +T+ +D V + + L GLCGNF+ +++
Sbjct: 1069 EVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTP 1128
Query: 1018 GGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRE 1077
+ N FG+SW P +P D L+ L ++ +K EC IL F
Sbjct: 1129 ENLELTNPQEFGSSWAAVECP--DTLDPRDMCVLNPL--REPFAKKECSILLSE--VFEI 1182
Query: 1078 CHSKLDPQGAVRDCVYDR--CLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLS 1135
CH +D +C+ D C G C +++ YA C G V WR+ LCP
Sbjct: 1183 CHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYD 1241
Query: 1136 C 1136
C
Sbjct: 1242 C 1242
Score = 98.6 bits (244), Expect = 8e-20
Identities = 82/297 (27%), Positives = 126/297 (42%), Gaps = 27/297 (9%)
Query: 455 CQVVGGKAGCVAESTA-VCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSV 513
C G C A C A GD HY TFDG +D +G C +V+ S+ +FSV
Sbjct: 967 CVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD----VSFSV 1022
Query: 514 EAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQS 573
+N + Y + R + +S+ G V D+ + P S + + V+
Sbjct: 1023 IVENVN------CYSSGMICRKF---ISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTW 1073
Query: 574 GPRAVVELVFGLV-VTYDWDCQLALSLPA--RFQDQVCGLCGNYNGDPADDFLTPDGALA 630
+ F +T WD + + + A ++Q Q+ GLCGN++ ++ TP+
Sbjct: 1074 RVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLEL 1133
Query: 631 PDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDT 690
+ EF SSW + C D C + + C +L L F +CH
Sbjct: 1134 TNPQEFGSSWAAVE----CPDTLDPR-DMCVLNPLREPFAKKECSIL--LSEVFEICHPV 1186
Query: 691 LDPRPFLEQCVYDL--CVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSC 745
+D F C+ D C GG+ C +SAYA C + G++V DWR+P CP C
Sbjct: 1187 VDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1242
Score = 92.4 bits (228), Expect = 6e-18
Identities = 117/502 (23%), Positives = 189/502 (37%), Gaps = 87/502 (17%)
Query: 2355 SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLH----DGRYYPLGEVFYPG 2410
S P+LS EG A + + TCVP+ + C+ +G+ + + +
Sbjct: 2025 SAPALSIVEGLAEALATTTEAN-----TSTTCVPIAEQDCVRHICLEGQLIRVNQSQHC- 2078
Query: 2411 PECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGR 2470
P+ CG G G C P EC AC RC + ++T DG
Sbjct: 2079 PQGAAPPRCGILGLAVRVGGDRCCPLWEC-------AC------RCSIFPDLSFVTFDGS 2125
Query: 2471 VYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRL-----------LVTVAGQVV 2519
L Y+L+Q DE ++ + + +L L + +A QV
Sbjct: 2126 HVALFKEAIYILSQ-----SPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVT 2180
Query: 2520 SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLM---SIPS 2576
++VTVD + V PV+ R+ G ++ T +++ + + L++ S S
Sbjct: 2181 IDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTS 2240
Query: 2577 PFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVET---FGAAWRAPGSSKGCGE------G 2627
+G GLCG +G+ ++D L +GS E F +W+ P S G+
Sbjct: 2241 KAQGH--GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDS 2298
Query: 2628 CGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDK 2687
C C CL + AC + P+ + C+ + ++Y +Q
Sbjct: 2299 CATTDCSPCL--RMVSNRTFSACHRFVPPE---SFCELWIRDTKYVQQP----------- 2342
Query: 2688 AFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTG- 2746
C +L Y A C V ++ WR +CP C + S Y C C+ G+ G
Sbjct: 2343 ---CVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGP 2398
Query: 2747 -----CTTRCFEGCECDDRFLLSQ---GVCIPVQDCGCTHN---GRYLPVNSSLLTSDCS 2795
C EGC C + +L + +CIP C CT + R L + S C
Sbjct: 2399 LDPEHCQV-LGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCC 2457
Query: 2796 ERCSCSSSSGLTCQAAGCPPGR 2817
+ C + + GCP R
Sbjct: 2458 QH-QCQAPDTIVPVDLGCPSPR 2478
Score = 91.3 bits (225), Expect = 1e-17
Identities = 115/456 (25%), Positives = 171/456 (37%), Gaps = 78/456 (17%)
Query: 419 GLAKAIGYATAADCGRTVLSPVEPSCEGMQCAAGQ-----------------RCQV---- 457
GLA+A+ T A+ T + E C C GQ RC +
Sbjct: 2034 GLAEALATTTEANTSTTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLA 2093
Query: 458 --VGGKAGC-VAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVE 514
VGG C + E C D + TFDG + Y + + S D+ L ++
Sbjct: 2094 VRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQ--SPDEMLTVHVLD 2151
Query: 515 AKNEHRGSRRVSYVGLVTVRA--YSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQ 572
K+ + G LV + +H V++ R V VD Q PVS R+
Sbjct: 2152 CKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRK-VTVDLQPVWPPVS--RYGFRIED 2208
Query: 573 SGPRAVVELVFGLVVTYDWDCQLALSLPARFQD-QVCGLCGNYNGDPADDFLTPDGAL-- 629
+G ++ + + + L + ++ Q GLCG +GD A+D DG++
Sbjct: 2209 TGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVG 2268
Query: 630 -APDAVEFASSWKLDDG------DYLCEDGCQN-NCPACTPGQAQHYEGDRLCGMLTKLD 681
A D F SW++ D C +C C R+ T
Sbjct: 2269 GAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCL----------RMVSNRT--- 2315
Query: 682 GPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANC 741
F+ CH + P F E + D V C L+ Y C + + + +WR C
Sbjct: 2316 --FSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCI-EWRRSDYC 2368
Query: 742 PLSCPANSRYELCGPAC--PTSCN----GAAAPSNCSGRPCVEGCVCLPGFV---ASGGA 792
P C ++S Y+ C AC P +C G P +C + EGCVC G +
Sbjct: 2369 PFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHC--QVLGEGCVCSEGTILHRRHSAL 2426
Query: 793 CVPASSCGCT-FQGLQLAPGQEVWADEL---CQRRC 824
C+P + C CT G+ A G E W L CQ +C
Sbjct: 2427 CIPEAKCACTDSMGVPRALG-ETWNSSLSGCCQHQC 2461
Score = 90.1 bits (222), Expect = 3e-17
Identities = 121/509 (23%), Positives = 184/509 (36%), Gaps = 82/509 (16%)
Query: 1216 CQEGGLVSCESSSCGPHEACQPSGGSLG---------CVAVGSSTCQAS--GDPHYTTFD 1264
C EG L+ S P A P G LG C + C+ S D + TFD
Sbjct: 2064 CLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFD 2123
Query: 1265 GRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQ 1324
G +Y+L+Q+ +H N+ N ++ + + +++
Sbjct: 2124 GSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDR 2183
Query: 1325 RQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQ 1384
KVTV+ + PV +I + H ++ +D ++ + + V
Sbjct: 2184 FNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMI-VEASKTSKA 2242
Query: 1385 QMCGLCGNYNGDPKDDFQKPNGSQAGNANE---FGNSWEEVVPDSPCLPPTPCPPGSEDC 1441
Q GLCG +GD +D +GS G A + F +SW+ VP S L D
Sbjct: 2243 QGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQ--VPSS--LTSVGQTRFRPDS 2298
Query: 1442 IPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSIL 1501
+ C P L ++S+ T S+CH+ V P+ + I D +
Sbjct: 2299 CATTDCSPCLR----------MVSNRT--FSACHRFVPPESFCELWIRDTKY----VQQP 2342
Query: 1502 CSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDG 1561
C + YV+ C +E WR +CP C +S Y+ C C P CQDG
Sbjct: 2343 CVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTAC-------EPPKTCQDG 2394
Query: 1562 ------------CAEGCQCDSGFLY---NGQACVPIQQCGCYHN-GV---YYEPEQTVLI 1602
EGC C G + + C+P +C C + GV E + L
Sbjct: 2395 ILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLS 2454
Query: 1603 DNCRQQCTCHAGKGMVCQEHSC---KPGQVCQPSGGILSCVTKDP-------------CH 1646
C+ Q C A +V + C +P + L TKDP C
Sbjct: 2455 GCCQHQ--CQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCE 2512
Query: 1647 GV--TCRPQETCKEQGGQGVCLPNYEATC 1673
G+ TCRP + C P+Y C
Sbjct: 2513 GLAPTCRPGHRLLTHFQEDSCCPSYSCEC 2541
Score = 84.7 bits (208), Expect = 1e-15
Identities = 105/415 (25%), Positives = 157/415 (37%), Gaps = 79/415 (19%)
Query: 2047 PASCGLGEVCGL-LPSGQHGCQPV--STAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAP 2103
P CG + GL + G C P+ C + D +VT DG Y+LS
Sbjct: 2084 PPRCG---ILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS 2140
Query: 2104 -----------CHGPPLGAEN---FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSAR- 2148
C LG N F + + N VT+ +N +T+ +
Sbjct: 2141 PDEMLTVHVLDCKSANLGHLNWPPFCLVMLN------MTHLAHQVTIDRFNRKVTVDLQP 2194
Query: 2149 -WPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRL----RVPA 2203
WP + F+++ H ++ + T S + + + S + + +
Sbjct: 2195 VWPPVSRYG-------FRIEDTGHMYM------ILTPSDIQIQWLHSSGLMIVEASKTSK 2241
Query: 2204 AYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECV-SKPCPSPCTPEQQESF 2262
A LCG+C D A+DL G VGGA+ + S PS T Q F
Sbjct: 2242 AQGHGLCGICDG---DAANDLTLKDGSV----VGGAEDPAPFLDSWQVPSSLTSVGQTRF 2294
Query: 2263 GGPDACGVISAT-------DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATY 2315
PD+C + + + CH VPP + + + D VQ C A+ Y
Sbjct: 2295 R-PDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVY 2349
Query: 2316 VAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSC--PVSCP----SLSAPEGCESAC 2369
VA C + EWRR D+CP C + S Y+ C +C P +C PE C+
Sbjct: 2350 VAMCHKFHVCI-EWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQ-VL 2407
Query: 2370 REGCVCDAGFVL---SGDTCVPVGQCGCLHD-GRYYPLGEVFYPGPE--CERRCE 2418
EGCVC G +L C+P +C C G LGE + C+ +C+
Sbjct: 2408 GEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQ 2462
Score = 78.6 bits (192), Expect = 9e-14
Identities = 119/493 (24%), Positives = 165/493 (33%), Gaps = 111/493 (22%)
Query: 816 ADELCQRRCTCNGATHQVTCRDKQSCPAGE---RCSVQNGLLG---------CYPDRFGT 863
A++ C R G +V Q CP G RC G+LG C P
Sbjct: 2055 AEQDCVRHICLEGQLIRVN--QSQHCPQGAAPPRC----GILGLAVRVGGDRCCPLWECA 2108
Query: 864 CQGS--GDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL----------------PAFRV 905
C+ S D +V+FDG Y+L S + + P V
Sbjct: 2109 CRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLV 2168
Query: 906 LVENEHRGSQTV--SYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVF 963
++ H Q + R V V+ + V V R G + D Y+ +D Q+Q
Sbjct: 2169 MLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRY--GFRIEDTGHMYMILTPSDIQIQWL 2226
Query: 964 RQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGG---G 1020
+V +K + LCG+C +GD A+DL L+ G G
Sbjct: 2227 HSSGLMIVEA---------------SKTSKAQGHGLCGIC---DGDAANDLTLKDGSVVG 2268
Query: 1021 QAANALAFGNSWQEE---TRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRE 1077
A + F +SWQ T G P C D ++ S F
Sbjct: 2269 GAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRT----------FSA 2318
Query: 1078 CHSKLDPQGA----VRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCP 1133
CH + P+ +RD Y + C AL Y A C + WR + CP
Sbjct: 2319 CHRFVPPESFCELWIRDTKYVQ--------QPCVALTVYVAMCHKFHVCIE-WRRSDYCP 2369
Query: 1134 LSCPPHSHYEACSYGC--PLSCGDLPVPGGCGSECH---EGCVCDEGFAL---SGESCLP 1185
C S Y+AC C P +C D + C EGCVC EG L C+P
Sbjct: 2370 FLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIP 2429
Query: 1186 LASCGCV-HQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGC 1244
A C C G G+T+ L C C + P LGC
Sbjct: 2430 EAKCACTDSMGVPRALGETW-------------NSSLSGCCQHQCQAPDTIVPV--DLGC 2474
Query: 1245 VAVGSSTCQASGD 1257
+ +C G+
Sbjct: 2475 PSPRPESCLRFGE 2487
Score = 63.9 bits (154), Expect = 2e-09
Identities = 113/434 (26%), Positives = 158/434 (36%), Gaps = 67/434 (15%)
Query: 1665 CLPNYEATCW--LWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQ 1722
C P +E C ++ D + +FDG Y+L+ + + LT + K+
Sbjct: 2101 CCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS-----PDEMLTVHVLDCKSA 2155
Query: 1723 NRGN---PAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQG 1779
N G+ P V ++ + L ++I + KV V + V PVS RI
Sbjct: 2156 NLGHLNWPPFCLV-MLNMTHLAHQVTIDRFN-RKVTVDLQPVWP--PVSRYGFRIEDTGH 2211
Query: 1780 ASKALLVADFGLQVSYDWNWR-VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTL--- 1835
L +D +Q + V+ + S G GLCG D + ND +G++
Sbjct: 2212 MYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLKDGSVVGG 2269
Query: 1836 ----APSIPIWG--GSWRAPGWDPLCWDECRGS-CPTCPEDRLEQYEGPGFCGPLASGTG 1888
AP + W S + G D C + C C L +
Sbjct: 2270 AEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPC----------------LRMVSN 2313
Query: 1889 GPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGC 1948
F+ CH VPPESF + + D C AL YVA C V IE WR C
Sbjct: 2314 RTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCIE-WRRSDYC 2368
Query: 1949 EITCPENSHYEVCGPPC--PASCPSP--APLTTPAVCEGPCVEGCQCDAGFVL---SADR 2001
C +S Y+ C C P +C PL P C+ EGC C G +L +
Sbjct: 2369 PFLCSSDSTYQACVTACEPPKTCQDGILGPL-DPEHCQ-VLGEGCVCSEGTILHRRHSAL 2426
Query: 2002 CVPLNNGCGCWANGTYHEAGSEFW---ADGTCSQWCRCGP-----GGGSLVCTPASC-GL 2052
C+P C C + A E W G C C+ G P SC
Sbjct: 2427 CIP-EAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRF 2485
Query: 2053 GEVCGLLPSGQHGC 2066
GEV LLP+ C
Sbjct: 2486 GEVALLLPTKDPCC 2499
Score = 32.7 bits (73), Expect = 5.6
Identities = 26/96 (27%), Positives = 33/96 (34%), Gaps = 17/96 (17%)
Query: 2721 CPAHSHYSICT-----------RTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCI 2769
CPA + C+ RTC+ LS C GC C L C
Sbjct: 883 CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLS--VSARGPCLSGCACPQGLLRHGDACF 940
Query: 2770 PVQDCGCTHNGR-YLPVNSSLLTSDCSERCSCSSSS 2804
++C CT G+ Y P + S C C C S
Sbjct: 941 LPEECPCTWKGKEYFP--GDQVMSPC-HTCVCQRGS 973
>gi|239744300 PREDICTED: otogelin isoform 2 [Homo sapiens]
Length = 2852
Score = 310 bits (793), Expect = 2e-83
Identities = 311/1219 (25%), Positives = 449/1219 (36%), Gaps = 194/1219 (15%)
Query: 831 HQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLL 890
H C ++ G RC + + P+R C+ G H +FDG + G +Y L
Sbjct: 49 HPAFCDCRRFNATGPRCQM---VYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTL 105
Query: 891 VGSCGQNAALPAFRVLVENEHR-GSQTVSYTRAVR---VEARGVKVAVRREYPG-QVLVD 945
VG +F + V N+ + GS + +RAV V + + +A + G +V +
Sbjct: 106 VGRHEPEGQ--SFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLP 163
Query: 946 DVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGN 1005
V+ Q G V +VR T+ +D + V K+ GLCGN
Sbjct: 164 HVMGSARLQQLAGYV---------IVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGN 214
Query: 1006 FNGDPADDLALRGGGQAANALAFGNSWQEETR---PGCGATEPGDCPKLDSLVAQQLQSK 1062
N DP DDL G + + F +SWQE+ PG + P L
Sbjct: 215 NNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVY 274
Query: 1063 NECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGAT 1122
+C L P PF CH+ + P C D C G C ALA YA AC AG
Sbjct: 275 EQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRP 332
Query: 1123 VHPWRSE-ELCPLSCPPHSH-YEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSG 1180
+ WR++ C + C + Y C CP SC C +GC C G
Sbjct: 333 LQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFED 392
Query: 1181 ESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGG 1240
C+ A C C GT +PPG C++ C C G C ++ C
Sbjct: 393 GGCVAPAECPCEFHGTLYPPGSVVKED--CNT-CTCTSGKW-ECSTAVC----------- 437
Query: 1241 SLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAW 1300
+ C +GD H+TTFDGRR+ F TC Y+LA++ + F V +N
Sbjct: 438 --------PAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSS----GTFTVTLQNAPC 485
Query: 1301 GNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKL--------PVVLANGQIRASQH 1352
G + VQ + L + R+ D+ L P +IR
Sbjct: 486 GLNQDGA----CVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS- 540
Query: 1353 GSDVVIETDFGLRVAYD---LVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQA 1409
+ + T+ G+RV YD L Y++ V + + GLCG +NG+ +DDF P G
Sbjct: 541 SVFLRVRTNVGVRVLYDREGLRLYLQ--VDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPE 598
Query: 1410 GNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTG 1469
FGNSW+ + SP + +P P C L+ + C +L+
Sbjct: 599 STPQLFGNSWKTLSACSPLVSGSPLDP----------CDVHLQAASYSVQACSVLTGEM- 647
Query: 1470 PLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCP 1529
+ C + P + C D C G LC+ + Y C+ G V+ C
Sbjct: 648 -FAPCSAFLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACA 704
Query: 1530 MECPPNSHYELCADTCSLGCSALSAPPQC---------QDGCAEGCQCDSGFLYNGQA-- 1578
+ C + Y C C C L++P C +D C EGC C + QA
Sbjct: 705 LSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADL 764
Query: 1579 CVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEH----SCKPGQV----- 1629
CVP QC C+ GV Y P + + C C G M C +C GQV
Sbjct: 765 CVPRNQCSCHFQGVDYPPGDSDI--PSLGHCHCKDGV-MSCDSRAPAAACPAGQVFVNCS 821
Query: 1630 -------------CQPSGGILSCVTKDPC------------HGVTC-------------- 1650
C+ LS + PC HG C
Sbjct: 822 DLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKE 881
Query: 1651 --------RPQETCKEQGGQGVC-LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLAT 1701
P TC Q G C L +TC +GD HY +FDG FDF G C L
Sbjct: 882 YFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHL-- 939
Query: 1702 TGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGV 1761
V + F+V +N N + + + +++ +G ++ + D+ G
Sbjct: 940 -----VKSTSDVSFSVIVENVNCYSSGMICRKFISI-NVGNSLIVFDDDSG--------- 984
Query: 1762 LTALPVSVADGRISVAQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCG 1818
P S D + V + F + + +D V V + G + GLCG
Sbjct: 985 -NPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCG 1043
Query: 1819 NMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSC---PTCPEDRLEQYE 1875
N D N+ P + +G SW A EC + C + L +
Sbjct: 1044 NFDLKTINEMRTPENLELTNPQEFGSSWAAV--------ECPDTLDPRDMCVLNPLREPF 1095
Query: 1876 GPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDRDILCKALASYVAACQ 1933
C L S F CH V F+ C+ D C GGD + C ++++Y C
Sbjct: 1096 AKKECSILLSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCC 1152
Query: 1934 AAGVVIEDWRAQVGCEITC 1952
GV + DWR C C
Sbjct: 1153 QHGVAV-DWRTPRLCPYDC 1170
Score = 296 bits (758), Expect = 2e-79
Identities = 305/1176 (25%), Positives = 449/1176 (38%), Gaps = 199/1176 (16%)
Query: 1667 PNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNR-G 1725
P ++ C WG H +FDG + G +Y L P + F++ N + G
Sbjct: 73 PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS-----FSIQVHNDPQCG 127
Query: 1726 NPAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALL 1785
+ + R V++ +G IH + V G+ LP + R+ Q A ++
Sbjct: 128 SSPYTCSRAVSLFFVGEQ-EIHLAK----EVTHGGMRVQLPHVMGSARLQ--QLAGYVIV 180
Query: 1786 VADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGS 1845
+++D V + + G GLCGN + +P +D V +G L + + S
Sbjct: 181 RHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHS 240
Query: 1846 WR--APGWDPLCWDECRGSCPTCPEDRLEQYEGP--GFCGPLASGTGGPFTTCHAHVPPE 1901
W+ AP P S P P L+Q G G + PF CHA+V P
Sbjct: 241 WQEQAPNQPP---GPTTSSLPRPP--CLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPL 295
Query: 1902 SFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV-GCEITCPENSH-YE 1959
F C D+C GD C+ALA Y AC AG ++ WR Q+ C + C E + Y
Sbjct: 296 PFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYN 355
Query: 1960 VCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHE 2019
C CPASC P + E CV+GC C G + CV C C +GT +
Sbjct: 356 ECIACCPASC---HPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE-CPCEFHGTLYP 411
Query: 2020 AGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGD 2079
GS D C+ C C G C+ A C AEC GD
Sbjct: 412 PGSVVKED--CNT-CTC--TSGKWECSTAVC--------------------PAECSVTGD 446
Query: 2080 PHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTLQI 2138
H+ T DG R+ F TC+Y+L+ + FTVT+ N G +Q + +SV++ +
Sbjct: 447 IHFTTFDGRRYTFPATCQYILA-----KSRSSGTFTVTLQNAPCGLNQDGACVQSVSVIL 501
Query: 2139 Y---NHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDS 2195
+ +TL+ L D + P+ D+ LS + V T G+ + +D +
Sbjct: 502 HQDPRRQVTLTQAGD-VLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREG 560
Query: 2196 F-VRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQGCGECV 2246
+ L+V + GLCG +N + DD + G P W+ A C V
Sbjct: 561 LRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA--CSPLV 618
Query: 2247 SKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPG 2306
S PC Q + AC V+ T APC + P YF+ C DAC+ G P
Sbjct: 619 SGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDACRC-GQP- 674
Query: 2307 GLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEGC- 2365
LC +A Y C+ G + R C L C A Y C C +C L++PE C
Sbjct: 675 CLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACG 734
Query: 2366 --------ESACREGCVC--DAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPG----- 2410
C EGC C D D CVP QC C G YP G+ P
Sbjct: 735 VDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCH 794
Query: 2411 -----PECERRCECG--PGGHV-----------------TCQE----------------- 2429
C+ R P G V TC++
Sbjct: 795 CKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGC 854
Query: 2430 ---------GAACGPHEECRL----------EDGVQACHATGCGR-------------CL 2457
G AC EEC + + CH C R C
Sbjct: 855 ACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCT 914
Query: 2458 ANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEK---NAAGDLQRLLVTV 2514
A G HY T DG +D G+C L + D FS+++E ++G + R
Sbjct: 915 AYGDRHYRTFDGLPFDFVGACKVHLVK----STSDVSFSVIVENVNCYSSGMICR----- 965
Query: 2515 AGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGR-------NMVLQTTKGLRLLFDGD 2567
+ +S+ G + V + P + E +V + + LL+D
Sbjct: 966 --KFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQR 1023
Query: 2568 AHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEG 2627
+ + ++G+L GLCGNF+ ++ P ++ + FG++W A C +
Sbjct: 1024 TTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAA----VECPDT 1079
Query: 2628 CGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDL--CAQKG 2685
P+ +C+ + + C L + F C V+ + ++ C+ D C+Q G
Sbjct: 1080 LDPR--DMCVLNPLREPFAKKECSILLSE--VFEICHPVVDVTWFYSNCLTDTCGCSQGG 1135
Query: 2686 DKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHC 2721
D C S++AY C GVAV WRT CP C
Sbjct: 1136 DCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1170
Score = 280 bits (716), Expect = 2e-74
Identities = 247/825 (29%), Positives = 336/825 (40%), Gaps = 105/825 (12%)
Query: 450 AAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLP 509
A G RCQ+V E ++CRA G H TFDG Y + G SYT+V +
Sbjct: 60 ATGPRCQMVYNAG---PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQ-- 114
Query: 510 AFSVEAKNE-------HRGSRRVS--YVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLP 560
+FS++ N+ + SR VS +VG + + +T G R +LP
Sbjct: 115 SFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHL---AKEVTHG--------GMRVQLP 163
Query: 561 VSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPAD 620
+ RL+ Q +V + +D + + + GLCGN N DP D
Sbjct: 164 HVMGSARLQ--QLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKD 221
Query: 621 DFLTPDGALAPDAVEFASSWKLDDGDY--------LCEDGCQNNCPACTPGQAQHYEGDR 672
D +T G L D VEF SW+ + L C P G + E
Sbjct: 222 DLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEA-- 279
Query: 673 LCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISV 732
L PF CH + P PF C DLC G+ + CR L+ YA+AC + G +
Sbjct: 280 ------LLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 333
Query: 733 GDWRSP-ANCPLSCPANS-RYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASG 790
WR+ C + C + Y C CP SC+ A+ + S CV+GC C G +
Sbjct: 334 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVD-SEIACVDGCYCPNGLIFED 392
Query: 791 GACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQ 850
G CV + C C F G PG V D C CTC + + CPA CSV
Sbjct: 393 GGCVAPAECPCEFHGTLYPPGSVVKED--C-NTCTCTSGKWECS---TAVCPA--ECSV- 443
Query: 851 NGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENE 910
+GD H+ +FDGRR+ F TC Y+L S F V ++N
Sbjct: 444 ----------------TGDIHFTTFDGRRYTFPATCQYILAKSRSSG----TFTVTLQNA 483
Query: 911 HRG-SQTVSYTRAVRVEA-RGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRD 968
G +Q + ++V V + + V G VL+ D + +P D ++ R
Sbjct: 484 PCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIP-PYTDDAFEIRRLSSV 542
Query: 969 AV-VRTDFGLTVTYDWNA-RVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANAL 1026
+ VRT+ G+ V YD R+ +V + E GLCG FNG+ DD G +
Sbjct: 543 FLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQ 602
Query: 1027 AFGNSWQEETRPGCGATEPGD-CPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQ 1085
FGNSW +T C G D + S C +L F C + L P
Sbjct: 603 LFGNSW--KTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEM--FAPCSAFLSPV 658
Query: 1086 GAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEAC 1145
C D C GQ LC LA YA C+ G V C LSC Y C
Sbjct: 659 PYFEQCRRDACRC-GQP-CLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPC 716
Query: 1146 SYGCPLSCGDLPVPGGCG---------SECHEGCVC--DEGFALSGESCLPLASCGCVHQ 1194
C +C DL P CG EC EGC C D + C+P C C Q
Sbjct: 717 VAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQ 776
Query: 1195 GTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSG 1239
G +PPG + P G CHC++ G++SC+S + P AC P+G
Sbjct: 777 GVDYPPGDSDIPSLG---HCHCKD-GVMSCDSRA--PAAAC-PAG 814
Score = 254 bits (649), Expect = 9e-67
Identities = 233/821 (28%), Positives = 317/821 (38%), Gaps = 90/821 (10%)
Query: 2040 GGSLVCTPASCGLGEVCGLLPSGQ--HGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCE 2097
GG V PA C P Q + P + C+AWG H T DG + G
Sbjct: 44 GGECV-HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGS 102
Query: 2098 YLLSAPCHGPPLGAENFTVTVANEHR-GSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD 2156
Y L H P ++F++ V N+ + GS + +R+V+L +++
Sbjct: 103 YTLVGR-HEPE--GQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQ---EIHLAKEVTHG 156
Query: 2157 GVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNY 2216
G+ V LP + S L+G V+V S +LA+DG S V +++ GLCGN
Sbjct: 157 GMRVQLPHVMGSARLQQLAGY-VIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNN 215
Query: 2217 NQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCT------PEQQESFGGPDACGV 2270
N DP DDL GK V E P P T P Q++ G GV
Sbjct: 216 NADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQ--GV 273
Query: 2271 ISATDGPLAP----CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQL 2326
+ L P CH V P + C D CQ G C A+A Y AC AG L
Sbjct: 274 YEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 333
Query: 2327 GEWRRP-DFCPLQCPAHSH-YELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGD 2384
WR C + C + Y C CP SC ++ E AC +GC C G +
Sbjct: 334 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDG 393
Query: 2385 TCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDG 2444
CV +C C G YP PG + C C G
Sbjct: 394 GCVAPAECPCEFHGTLYP------PGSVVKEDCNT-------------------CTCTSG 428
Query: 2445 VQACHATGC-GRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNA 2503
C C C G IH+ T DGR Y +C Y+LA+ F++ L+
Sbjct: 429 KWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAK----SRSSGTFTVTLQNAP 484
Query: 2504 AG---------DLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVL 2554
G + +L + V+L Q V + + +P ++ L
Sbjct: 485 CGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFL 544
Query: 2555 Q--TTKGLRLLFDGDA-HLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETF 2611
+ T G+R+L+D + L + + + GLCG FNGN DDF+ P G S+ + F
Sbjct: 545 RVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLF 604
Query: 2612 GAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSE 2671
G +W+ + G C V L + A Y S +AC L FA C A LSP
Sbjct: 605 GNSWKTLSACSPLVSGSPLDPCDVHL--QAASY-SVQACSVLTGEM--FAPCSAFLSPVP 659
Query: 2672 YFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICT 2731
YF QC D C + + LC +LA Y C+ G+ V C L C A YS C
Sbjct: 660 YFEQCRRDAC--RCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCV 717
Query: 2732 RTCQGSCAALSGLTGC---------TTRCFEGCEC-DDRFLLSQG-VCIPVQDCGCTHNG 2780
C +C L+ C C EGC C D +L +Q +C+P C C G
Sbjct: 718 APCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQG 777
Query: 2781 RYLPVNSSLLTSDCSERCSCSS---SSGLTCQAAGCPPGRV 2818
P S + S C C S AA CP G+V
Sbjct: 778 VDYPPGDSDIPS--LGHCHCKDGVMSCDSRAPAAACPAGQV 816
Score = 161 bits (408), Expect = 8e-39
Identities = 154/588 (26%), Positives = 227/588 (38%), Gaps = 47/588 (7%)
Query: 2416 RCECGPGGHVTCQEGAACGPHE--ECRLEDGV----QACHATGCGR---CLANGGIHYIT 2466
R +C P +C G C +CR + Q + G R C A G H T
Sbjct: 30 RAKCAPSYLFSCFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVET 89
Query: 2467 LDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRL-------LVTVAGQVV 2519
DG Y L G SY L V +P + FSI + + L V Q +
Sbjct: 90 FDGLYYYLSGKGSYTL--VGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEI 147
Query: 2520 SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFR 2579
LA+ +VT G V LP +G R+ ++++ L +DG + + + +
Sbjct: 148 HLAK--EVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELL 205
Query: 2580 GRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAE 2639
G GLCGN N + DD V +G V F +W+ ++ G P CL +
Sbjct: 206 GWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQ 265
Query: 2640 ETAPYES-NEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYT 2698
+ E C L P PF C A +SP + C DLC GD A CR+LA Y
Sbjct: 266 NPGTMQGVYEQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYA 323
Query: 2699 AACQAAGVAVKPWRTD-SFCPLHCPAHSH-YSICTRTCQGSCAALSGLTGCTTRCFEGCE 2756
AC AG ++ WRT C +HC + Y+ C C SC + C +GC
Sbjct: 324 RACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCY 383
Query: 2757 CDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPG 2816
C + + G C+ +C C +G P S++ DC+ C+C+S C A CP
Sbjct: 384 CPNGLIFEDGGCVAPAECPCEFHGTLYP-PGSVVKEDCN-TCTCTSGK-WECSTAVCP-- 438
Query: 2817 RVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYR 2876
AE C ++ + TTFDG R + Y L+ T+
Sbjct: 439 ------AE----------CSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQN 482
Query: 2877 VVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDG 2936
+ ++V + VTLT V + +P + + R
Sbjct: 483 APCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSV 542
Query: 2937 SLLVRQKAGVQVWLGANG-KVAVIVSNDHAGKLCGACGNFDGDQTNDW 2983
L VR GV+V G ++ + V G CG F+G+ +D+
Sbjct: 543 FLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDF 590
Score = 115 bits (287), Expect = 9e-25
Identities = 111/421 (26%), Positives = 162/421 (38%), Gaps = 61/421 (14%)
Query: 729 GISVGDWRSPANCPLSCPANSRYELCGP-------ACPTSCNGAAAPSNCSGR-PCVEGC 780
G+ D R+PA +CPA + C + +C + S R PC+ GC
Sbjct: 798 GVMSCDSRAPA---AACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGC 854
Query: 781 VCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQS 840
C G + G AC C CT++G + PG +V + C C C + Q T S
Sbjct: 855 ACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSP--C-HTCVCQRGSFQCTLHPCAS 911
Query: 841 CPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL 900
TC GD HY +FDG FDF+G C LV S
Sbjct: 912 ----------------------TCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD---- 945
Query: 901 PAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADG-- 958
+F V+VEN + S + + + + + V DD P D
Sbjct: 946 VSFSVIVENVNCYSSGMICRKFISINVGNSLI---------VFDDDSGNPSPESFLDDKQ 996
Query: 959 QVQVFRQGRDAVVR-TDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALR 1017
+V +R G +V +T+ +D V + + L GLCGNF+ +++
Sbjct: 997 EVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTP 1056
Query: 1018 GGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRE 1077
+ N FG+SW P +P D L+ L ++ +K EC IL F
Sbjct: 1057 ENLELTNPQEFGSSWAAVECP--DTLDPRDMCVLNPL--REPFAKKECSILLSE--VFEI 1110
Query: 1078 CHSKLDPQGAVRDCVYDR--CLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLS 1135
CH +D +C+ D C G C +++ YA C G V WR+ LCP
Sbjct: 1111 CHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYD 1169
Query: 1136 C 1136
C
Sbjct: 1170 C 1170
Score = 98.6 bits (244), Expect = 8e-20
Identities = 82/297 (27%), Positives = 126/297 (42%), Gaps = 27/297 (9%)
Query: 455 CQVVGGKAGCVAESTA-VCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSV 513
C G C A C A GD HY TFDG +D +G C +V+ S+ +FSV
Sbjct: 895 CVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD----VSFSV 950
Query: 514 EAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQS 573
+N + Y + R + +S+ G V D+ + P S + + V+
Sbjct: 951 IVENVN------CYSSGMICRKF---ISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTW 1001
Query: 574 GPRAVVELVFGLV-VTYDWDCQLALSLPA--RFQDQVCGLCGNYNGDPADDFLTPDGALA 630
+ F +T WD + + + A ++Q Q+ GLCGN++ ++ TP+
Sbjct: 1002 RVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLEL 1061
Query: 631 PDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDT 690
+ EF SSW + C D C + + C +L L F +CH
Sbjct: 1062 TNPQEFGSSWAAVE----CPDTLDPR-DMCVLNPLREPFAKKECSIL--LSEVFEICHPV 1114
Query: 691 LDPRPFLEQCVYDL--CVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSC 745
+D F C+ D C GG+ C +SAYA C + G++V DWR+P CP C
Sbjct: 1115 VDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1170
Score = 92.4 bits (228), Expect = 6e-18
Identities = 117/502 (23%), Positives = 189/502 (37%), Gaps = 87/502 (17%)
Query: 2355 SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLH----DGRYYPLGEVFYPG 2410
S P+LS EG A + + TCVP+ + C+ +G+ + + +
Sbjct: 1953 SAPALSIVEGLAEALATTTEAN-----TSTTCVPIAEQDCVRHICLEGQLIRVNQSQHC- 2006
Query: 2411 PECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGR 2470
P+ CG G G C P EC AC RC + ++T DG
Sbjct: 2007 PQGAAPPRCGILGLAVRVGGDRCCPLWEC-------AC------RCSIFPDLSFVTFDGS 2053
Query: 2471 VYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRL-----------LVTVAGQVV 2519
L Y+L+Q DE ++ + + +L L + +A QV
Sbjct: 2054 HVALFKEAIYILSQ-----SPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVT 2108
Query: 2520 SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLM---SIPS 2576
++VTVD + V PV+ R+ G ++ T +++ + + L++ S S
Sbjct: 2109 IDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTS 2168
Query: 2577 PFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVET---FGAAWRAPGSSKGCGE------G 2627
+G GLCG +G+ ++D L +GS E F +W+ P S G+
Sbjct: 2169 KAQGH--GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDS 2226
Query: 2628 CGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDK 2687
C C CL + AC + P+ + C+ + ++Y +Q
Sbjct: 2227 CATTDCSPCL--RMVSNRTFSACHRFVPPE---SFCELWIRDTKYVQQP----------- 2270
Query: 2688 AFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTG- 2746
C +L Y A C V ++ WR +CP C + S Y C C+ G+ G
Sbjct: 2271 ---CVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGP 2326
Query: 2747 -----CTTRCFEGCECDDRFLLSQ---GVCIPVQDCGCTHN---GRYLPVNSSLLTSDCS 2795
C EGC C + +L + +CIP C CT + R L + S C
Sbjct: 2327 LDPEHCQV-LGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCC 2385
Query: 2796 ERCSCSSSSGLTCQAAGCPPGR 2817
+ C + + GCP R
Sbjct: 2386 QH-QCQAPDTIVPVDLGCPSPR 2406
Score = 91.3 bits (225), Expect = 1e-17
Identities = 115/456 (25%), Positives = 171/456 (37%), Gaps = 78/456 (17%)
Query: 419 GLAKAIGYATAADCGRTVLSPVEPSCEGMQCAAGQ-----------------RCQV---- 457
GLA+A+ T A+ T + E C C GQ RC +
Sbjct: 1962 GLAEALATTTEANTSTTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLA 2021
Query: 458 --VGGKAGC-VAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVE 514
VGG C + E C D + TFDG + Y + + S D+ L ++
Sbjct: 2022 VRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQ--SPDEMLTVHVLD 2079
Query: 515 AKNEHRGSRRVSYVGLVTVRA--YSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQ 572
K+ + G LV + +H V++ R V VD Q PVS R+
Sbjct: 2080 CKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRK-VTVDLQPVWPPVS--RYGFRIED 2136
Query: 573 SGPRAVVELVFGLVVTYDWDCQLALSLPARFQD-QVCGLCGNYNGDPADDFLTPDGAL-- 629
+G ++ + + + L + ++ Q GLCG +GD A+D DG++
Sbjct: 2137 TGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVG 2196
Query: 630 -APDAVEFASSWKLDDG------DYLCEDGCQN-NCPACTPGQAQHYEGDRLCGMLTKLD 681
A D F SW++ D C +C C R+ T
Sbjct: 2197 GAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCL----------RMVSNRT--- 2243
Query: 682 GPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANC 741
F+ CH + P F E + D V C L+ Y C + + + +WR C
Sbjct: 2244 --FSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCI-EWRRSDYC 2296
Query: 742 PLSCPANSRYELCGPAC--PTSCN----GAAAPSNCSGRPCVEGCVCLPGFV---ASGGA 792
P C ++S Y+ C AC P +C G P +C + EGCVC G +
Sbjct: 2297 PFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHC--QVLGEGCVCSEGTILHRRHSAL 2354
Query: 793 CVPASSCGCT-FQGLQLAPGQEVWADEL---CQRRC 824
C+P + C CT G+ A G E W L CQ +C
Sbjct: 2355 CIPEAKCACTDSMGVPRALG-ETWNSSLSGCCQHQC 2389
Score = 90.1 bits (222), Expect = 3e-17
Identities = 121/509 (23%), Positives = 184/509 (36%), Gaps = 82/509 (16%)
Query: 1216 CQEGGLVSCESSSCGPHEACQPSGGSLG---------CVAVGSSTCQAS--GDPHYTTFD 1264
C EG L+ S P A P G LG C + C+ S D + TFD
Sbjct: 1992 CLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFD 2051
Query: 1265 GRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQ 1324
G +Y+L+Q+ +H N+ N ++ + + +++
Sbjct: 2052 GSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDR 2111
Query: 1325 RQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQ 1384
KVTV+ + PV +I + H ++ +D ++ + + V
Sbjct: 2112 FNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMI-VEASKTSKA 2170
Query: 1385 QMCGLCGNYNGDPKDDFQKPNGSQAGNANE---FGNSWEEVVPDSPCLPPTPCPPGSEDC 1441
Q GLCG +GD +D +GS G A + F +SW+ VP S L D
Sbjct: 2171 QGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQ--VPSS--LTSVGQTRFRPDS 2226
Query: 1442 IPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSIL 1501
+ C P L ++S+ T S+CH+ V P+ + I D +
Sbjct: 2227 CATTDCSPCLR----------MVSNRT--FSACHRFVPPESFCELWIRDTKY----VQQP 2270
Query: 1502 CSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDG 1561
C + YV+ C +E WR +CP C +S Y+ C C P CQDG
Sbjct: 2271 CVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTAC-------EPPKTCQDG 2322
Query: 1562 ------------CAEGCQCDSGFLY---NGQACVPIQQCGCYHN-GV---YYEPEQTVLI 1602
EGC C G + + C+P +C C + GV E + L
Sbjct: 2323 ILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLS 2382
Query: 1603 DNCRQQCTCHAGKGMVCQEHSC---KPGQVCQPSGGILSCVTKDP-------------CH 1646
C+ Q C A +V + C +P + L TKDP C
Sbjct: 2383 GCCQHQ--CQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCE 2440
Query: 1647 GV--TCRPQETCKEQGGQGVCLPNYEATC 1673
G+ TCRP + C P+Y C
Sbjct: 2441 GLAPTCRPGHRLLTHFQEDSCCPSYSCEC 2469
Score = 84.7 bits (208), Expect = 1e-15
Identities = 105/415 (25%), Positives = 157/415 (37%), Gaps = 79/415 (19%)
Query: 2047 PASCGLGEVCGL-LPSGQHGCQPV--STAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAP 2103
P CG + GL + G C P+ C + D +VT DG Y+LS
Sbjct: 2012 PPRCG---ILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS 2068
Query: 2104 -----------CHGPPLGAEN---FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSAR- 2148
C LG N F + + N VT+ +N +T+ +
Sbjct: 2069 PDEMLTVHVLDCKSANLGHLNWPPFCLVMLN------MTHLAHQVTIDRFNRKVTVDLQP 2122
Query: 2149 -WPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRL----RVPA 2203
WP + F+++ H ++ + T S + + + S + + +
Sbjct: 2123 VWPPVSRYG-------FRIEDTGHMYM------ILTPSDIQIQWLHSSGLMIVEASKTSK 2169
Query: 2204 AYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECV-SKPCPSPCTPEQQESF 2262
A LCG+C D A+DL G VGGA+ + S PS T Q F
Sbjct: 2170 AQGHGLCGICDG---DAANDLTLKDGSV----VGGAEDPAPFLDSWQVPSSLTSVGQTRF 2222
Query: 2263 GGPDACGVISAT-------DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATY 2315
PD+C + + + CH VPP + + + D VQ C A+ Y
Sbjct: 2223 R-PDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVY 2277
Query: 2316 VAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSC--PVSCP----SLSAPEGCESAC 2369
VA C + EWRR D+CP C + S Y+ C +C P +C PE C+
Sbjct: 2278 VAMCHKFHVCI-EWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQ-VL 2335
Query: 2370 REGCVCDAGFVL---SGDTCVPVGQCGCLHD-GRYYPLGEVFYPGPE--CERRCE 2418
EGCVC G +L C+P +C C G LGE + C+ +C+
Sbjct: 2336 GEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQ 2390
Score = 78.6 bits (192), Expect = 9e-14
Identities = 119/493 (24%), Positives = 165/493 (33%), Gaps = 111/493 (22%)
Query: 816 ADELCQRRCTCNGATHQVTCRDKQSCPAGE---RCSVQNGLLG---------CYPDRFGT 863
A++ C R G +V Q CP G RC G+LG C P
Sbjct: 1983 AEQDCVRHICLEGQLIRVN--QSQHCPQGAAPPRC----GILGLAVRVGGDRCCPLWECA 2036
Query: 864 CQGS--GDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL----------------PAFRV 905
C+ S D +V+FDG Y+L S + + P V
Sbjct: 2037 CRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLV 2096
Query: 906 LVENEHRGSQTV--SYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVF 963
++ H Q + R V V+ + V V R G + D Y+ +D Q+Q
Sbjct: 2097 MLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRY--GFRIEDTGHMYMILTPSDIQIQWL 2154
Query: 964 RQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGG---G 1020
+V +K + LCG+C +GD A+DL L+ G G
Sbjct: 2155 HSSGLMIVEA---------------SKTSKAQGHGLCGIC---DGDAANDLTLKDGSVVG 2196
Query: 1021 QAANALAFGNSWQEE---TRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRE 1077
A + F +SWQ T G P C D ++ S F
Sbjct: 2197 GAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRT----------FSA 2246
Query: 1078 CHSKLDPQGA----VRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCP 1133
CH + P+ +RD Y + C AL Y A C + WR + CP
Sbjct: 2247 CHRFVPPESFCELWIRDTKYVQ--------QPCVALTVYVAMCHKFHVCIE-WRRSDYCP 2297
Query: 1134 LSCPPHSHYEACSYGC--PLSCGDLPVPGGCGSECH---EGCVCDEGFAL---SGESCLP 1185
C S Y+AC C P +C D + C EGCVC EG L C+P
Sbjct: 2298 FLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIP 2357
Query: 1186 LASCGCV-HQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGC 1244
A C C G G+T+ L C C + P LGC
Sbjct: 2358 EAKCACTDSMGVPRALGETW-------------NSSLSGCCQHQCQAPDTIVPV--DLGC 2402
Query: 1245 VAVGSSTCQASGD 1257
+ +C G+
Sbjct: 2403 PSPRPESCLRFGE 2415
Score = 63.9 bits (154), Expect = 2e-09
Identities = 113/434 (26%), Positives = 158/434 (36%), Gaps = 67/434 (15%)
Query: 1665 CLPNYEATCW--LWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQ 1722
C P +E C ++ D + +FDG Y+L+ + + LT + K+
Sbjct: 2029 CCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS-----PDEMLTVHVLDCKSA 2083
Query: 1723 NRGN---PAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQG 1779
N G+ P V ++ + L ++I + KV V + V PVS RI
Sbjct: 2084 NLGHLNWPPFCLV-MLNMTHLAHQVTIDRFN-RKVTVDLQPVWP--PVSRYGFRIEDTGH 2139
Query: 1780 ASKALLVADFGLQVSYDWNWR-VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTL--- 1835
L +D +Q + V+ + S G GLCG D + ND +G++
Sbjct: 2140 MYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLKDGSVVGG 2197
Query: 1836 ----APSIPIWG--GSWRAPGWDPLCWDECRGS-CPTCPEDRLEQYEGPGFCGPLASGTG 1888
AP + W S + G D C + C C L +
Sbjct: 2198 AEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPC----------------LRMVSN 2241
Query: 1889 GPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGC 1948
F+ CH VPPESF + + D C AL YVA C V IE WR C
Sbjct: 2242 RTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCIE-WRRSDYC 2296
Query: 1949 EITCPENSHYEVCGPPC--PASCPSP--APLTTPAVCEGPCVEGCQCDAGFVL---SADR 2001
C +S Y+ C C P +C PL P C+ EGC C G +L +
Sbjct: 2297 PFLCSSDSTYQACVTACEPPKTCQDGILGPL-DPEHCQ-VLGEGCVCSEGTILHRRHSAL 2354
Query: 2002 CVPLNNGCGCWANGTYHEAGSEFW---ADGTCSQWCRCGP-----GGGSLVCTPASC-GL 2052
C+P C C + A E W G C C+ G P SC
Sbjct: 2355 CIP-EAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRF 2413
Query: 2053 GEVCGLLPSGQHGC 2066
GEV LLP+ C
Sbjct: 2414 GEVALLLPTKDPCC 2427
Score = 32.7 bits (73), Expect = 5.6
Identities = 26/96 (27%), Positives = 33/96 (34%), Gaps = 17/96 (17%)
Query: 2721 CPAHSHYSICT-----------RTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCI 2769
CPA + C+ RTC+ LS C GC C L C
Sbjct: 811 CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLS--VSARGPCLSGCACPQGLLRHGDACF 868
Query: 2770 PVQDCGCTHNGR-YLPVNSSLLTSDCSERCSCSSSS 2804
++C CT G+ Y P + S C C C S
Sbjct: 869 LPEECPCTWKGKEYFP--GDQVMSPC-HTCVCQRGS 901
>gi|239744298 PREDICTED: otogelin isoform 1 [Homo sapiens]
Length = 2924
Score = 310 bits (793), Expect = 2e-83
Identities = 311/1219 (25%), Positives = 449/1219 (36%), Gaps = 194/1219 (15%)
Query: 831 HQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLL 890
H C ++ G RC + + P+R C+ G H +FDG + G +Y L
Sbjct: 121 HPAFCDCRRFNATGPRCQM---VYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTL 177
Query: 891 VGSCGQNAALPAFRVLVENEHR-GSQTVSYTRAVR---VEARGVKVAVRREYPG-QVLVD 945
VG +F + V N+ + GS + +RAV V + + +A + G +V +
Sbjct: 178 VGRHEPEGQ--SFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLP 235
Query: 946 DVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGN 1005
V+ Q G V +VR T+ +D + V K+ GLCGN
Sbjct: 236 HVMGSARLQQLAGYV---------IVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGN 286
Query: 1006 FNGDPADDLALRGGGQAANALAFGNSWQEETR---PGCGATEPGDCPKLDSLVAQQLQSK 1062
N DP DDL G + + F +SWQE+ PG + P L
Sbjct: 287 NNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVY 346
Query: 1063 NECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGAT 1122
+C L P PF CH+ + P C D C G C ALA YA AC AG
Sbjct: 347 EQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRP 404
Query: 1123 VHPWRSE-ELCPLSCPPHSH-YEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSG 1180
+ WR++ C + C + Y C CP SC C +GC C G
Sbjct: 405 LQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFED 464
Query: 1181 ESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGG 1240
C+ A C C GT +PPG C++ C C G C ++ C
Sbjct: 465 GGCVAPAECPCEFHGTLYPPGSVVKED--CNT-CTCTSGKW-ECSTAVC----------- 509
Query: 1241 SLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAW 1300
+ C +GD H+TTFDGRR+ F TC Y+LA++ + F V +N
Sbjct: 510 --------PAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSS----GTFTVTLQNAPC 557
Query: 1301 GNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKL--------PVVLANGQIRASQH 1352
G + VQ + L + R+ D+ L P +IR
Sbjct: 558 GLNQDGA----CVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS- 612
Query: 1353 GSDVVIETDFGLRVAYD---LVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQA 1409
+ + T+ G+RV YD L Y++ V + + GLCG +NG+ +DDF P G
Sbjct: 613 SVFLRVRTNVGVRVLYDREGLRLYLQ--VDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPE 670
Query: 1410 GNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTG 1469
FGNSW+ + SP + +P P C L+ + C +L+
Sbjct: 671 STPQLFGNSWKTLSACSPLVSGSPLDP----------CDVHLQAASYSVQACSVLTGEM- 719
Query: 1470 PLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCP 1529
+ C + P + C D C G LC+ + Y C+ G V+ C
Sbjct: 720 -FAPCSAFLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACA 776
Query: 1530 MECPPNSHYELCADTCSLGCSALSAPPQC---------QDGCAEGCQCDSGFLYNGQA-- 1578
+ C + Y C C C L++P C +D C EGC C + QA
Sbjct: 777 LSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADL 836
Query: 1579 CVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEH----SCKPGQV----- 1629
CVP QC C+ GV Y P + + C C G M C +C GQV
Sbjct: 837 CVPRNQCSCHFQGVDYPPGDSDI--PSLGHCHCKDGV-MSCDSRAPAAACPAGQVFVNCS 893
Query: 1630 -------------CQPSGGILSCVTKDPC------------HGVTC-------------- 1650
C+ LS + PC HG C
Sbjct: 894 DLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKE 953
Query: 1651 --------RPQETCKEQGGQGVC-LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLAT 1701
P TC Q G C L +TC +GD HY +FDG FDF G C L
Sbjct: 954 YFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHL-- 1011
Query: 1702 TGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGV 1761
V + F+V +N N + + + +++ +G ++ + D+ G
Sbjct: 1012 -----VKSTSDVSFSVIVENVNCYSSGMICRKFISI-NVGNSLIVFDDDSG--------- 1056
Query: 1762 LTALPVSVADGRISVAQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCG 1818
P S D + V + F + + +D V V + G + GLCG
Sbjct: 1057 -NPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCG 1115
Query: 1819 NMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSC---PTCPEDRLEQYE 1875
N D N+ P + +G SW A EC + C + L +
Sbjct: 1116 NFDLKTINEMRTPENLELTNPQEFGSSWAAV--------ECPDTLDPRDMCVLNPLREPF 1167
Query: 1876 GPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDRDILCKALASYVAACQ 1933
C L S F CH V F+ C+ D C GGD + C ++++Y C
Sbjct: 1168 AKKECSILLSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCC 1224
Query: 1934 AAGVVIEDWRAQVGCEITC 1952
GV + DWR C C
Sbjct: 1225 QHGVAV-DWRTPRLCPYDC 1242
Score = 296 bits (758), Expect = 2e-79
Identities = 305/1176 (25%), Positives = 449/1176 (38%), Gaps = 199/1176 (16%)
Query: 1667 PNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNR-G 1725
P ++ C WG H +FDG + G +Y L P + F++ N + G
Sbjct: 145 PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS-----FSIQVHNDPQCG 199
Query: 1726 NPAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALL 1785
+ + R V++ +G IH + V G+ LP + R+ Q A ++
Sbjct: 200 SSPYTCSRAVSLFFVGEQ-EIHLAK----EVTHGGMRVQLPHVMGSARLQ--QLAGYVIV 252
Query: 1786 VADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGS 1845
+++D V + + G GLCGN + +P +D V +G L + + S
Sbjct: 253 RHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHS 312
Query: 1846 WR--APGWDPLCWDECRGSCPTCPEDRLEQYEGP--GFCGPLASGTGGPFTTCHAHVPPE 1901
W+ AP P S P P L+Q G G + PF CHA+V P
Sbjct: 313 WQEQAPNQPP---GPTTSSLPRPP--CLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPL 367
Query: 1902 SFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV-GCEITCPENSH-YE 1959
F C D+C GD C+ALA Y AC AG ++ WR Q+ C + C E + Y
Sbjct: 368 PFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYN 427
Query: 1960 VCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHE 2019
C CPASC P + E CV+GC C G + CV C C +GT +
Sbjct: 428 ECIACCPASC---HPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE-CPCEFHGTLYP 483
Query: 2020 AGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGD 2079
GS D C+ C C G C+ A C AEC GD
Sbjct: 484 PGSVVKED--CNT-CTC--TSGKWECSTAVC--------------------PAECSVTGD 518
Query: 2080 PHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTLQI 2138
H+ T DG R+ F TC+Y+L+ + FTVT+ N G +Q + +SV++ +
Sbjct: 519 IHFTTFDGRRYTFPATCQYILA-----KSRSSGTFTVTLQNAPCGLNQDGACVQSVSVIL 573
Query: 2139 Y---NHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDS 2195
+ +TL+ L D + P+ D+ LS + V T G+ + +D +
Sbjct: 574 HQDPRRQVTLTQAGD-VLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREG 632
Query: 2196 F-VRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQGCGECV 2246
+ L+V + GLCG +N + DD + G P W+ A C V
Sbjct: 633 LRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA--CSPLV 690
Query: 2247 SKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPG 2306
S PC Q + AC V+ T APC + P YF+ C DAC+ G P
Sbjct: 691 SGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDACRC-GQP- 746
Query: 2307 GLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEGC- 2365
LC +A Y C+ G + R C L C A Y C C +C L++PE C
Sbjct: 747 CLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACG 806
Query: 2366 --------ESACREGCVC--DAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPG----- 2410
C EGC C D D CVP QC C G YP G+ P
Sbjct: 807 VDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCH 866
Query: 2411 -----PECERRCECG--PGGHV-----------------TCQE----------------- 2429
C+ R P G V TC++
Sbjct: 867 CKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGC 926
Query: 2430 ---------GAACGPHEECRL----------EDGVQACHATGCGR-------------CL 2457
G AC EEC + + CH C R C
Sbjct: 927 ACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCT 986
Query: 2458 ANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEK---NAAGDLQRLLVTV 2514
A G HY T DG +D G+C L + D FS+++E ++G + R
Sbjct: 987 AYGDRHYRTFDGLPFDFVGACKVHLVK----STSDVSFSVIVENVNCYSSGMICR----- 1037
Query: 2515 AGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGR-------NMVLQTTKGLRLLFDGD 2567
+ +S+ G + V + P + E +V + + LL+D
Sbjct: 1038 --KFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQR 1095
Query: 2568 AHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEG 2627
+ + ++G+L GLCGNF+ ++ P ++ + FG++W A C +
Sbjct: 1096 TTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAA----VECPDT 1151
Query: 2628 CGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDL--CAQKG 2685
P+ +C+ + + C L + F C V+ + ++ C+ D C+Q G
Sbjct: 1152 LDPR--DMCVLNPLREPFAKKECSILLSE--VFEICHPVVDVTWFYSNCLTDTCGCSQGG 1207
Query: 2686 DKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHC 2721
D C S++AY C GVAV WRT CP C
Sbjct: 1208 DCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1242
Score = 280 bits (716), Expect = 2e-74
Identities = 247/825 (29%), Positives = 336/825 (40%), Gaps = 105/825 (12%)
Query: 450 AAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLP 509
A G RCQ+V E ++CRA G H TFDG Y + G SYT+V +
Sbjct: 132 ATGPRCQMVYNAG---PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQ-- 186
Query: 510 AFSVEAKNE-------HRGSRRVS--YVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLP 560
+FS++ N+ + SR VS +VG + + +T G R +LP
Sbjct: 187 SFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHL---AKEVTHG--------GMRVQLP 235
Query: 561 VSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPAD 620
+ RL+ Q +V + +D + + + GLCGN N DP D
Sbjct: 236 HVMGSARLQ--QLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKD 293
Query: 621 DFLTPDGALAPDAVEFASSWKLDDGDY--------LCEDGCQNNCPACTPGQAQHYEGDR 672
D +T G L D VEF SW+ + L C P G + E
Sbjct: 294 DLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEA-- 351
Query: 673 LCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISV 732
L PF CH + P PF C DLC G+ + CR L+ YA+AC + G +
Sbjct: 352 ------LLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 405
Query: 733 GDWRSP-ANCPLSCPANS-RYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASG 790
WR+ C + C + Y C CP SC+ A+ + S CV+GC C G +
Sbjct: 406 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVD-SEIACVDGCYCPNGLIFED 464
Query: 791 GACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQ 850
G CV + C C F G PG V D C CTC + + CPA CSV
Sbjct: 465 GGCVAPAECPCEFHGTLYPPGSVVKED--C-NTCTCTSGKWECS---TAVCPA--ECSV- 515
Query: 851 NGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENE 910
+GD H+ +FDGRR+ F TC Y+L S F V ++N
Sbjct: 516 ----------------TGDIHFTTFDGRRYTFPATCQYILAKSRSSG----TFTVTLQNA 555
Query: 911 HRG-SQTVSYTRAVRVEA-RGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRD 968
G +Q + ++V V + + V G VL+ D + +P D ++ R
Sbjct: 556 PCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIP-PYTDDAFEIRRLSSV 614
Query: 969 AV-VRTDFGLTVTYDWNA-RVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANAL 1026
+ VRT+ G+ V YD R+ +V + E GLCG FNG+ DD G +
Sbjct: 615 FLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQ 674
Query: 1027 AFGNSWQEETRPGCGATEPGD-CPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQ 1085
FGNSW +T C G D + S C +L F C + L P
Sbjct: 675 LFGNSW--KTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEM--FAPCSAFLSPV 730
Query: 1086 GAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEAC 1145
C D C GQ LC LA YA C+ G V C LSC Y C
Sbjct: 731 PYFEQCRRDACRC-GQP-CLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPC 788
Query: 1146 SYGCPLSCGDLPVPGGCG---------SECHEGCVC--DEGFALSGESCLPLASCGCVHQ 1194
C +C DL P CG EC EGC C D + C+P C C Q
Sbjct: 789 VAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQ 848
Query: 1195 GTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSG 1239
G +PPG + P G CHC++ G++SC+S + P AC P+G
Sbjct: 849 GVDYPPGDSDIPSLG---HCHCKD-GVMSCDSRA--PAAAC-PAG 886
Score = 254 bits (649), Expect = 9e-67
Identities = 233/821 (28%), Positives = 317/821 (38%), Gaps = 90/821 (10%)
Query: 2040 GGSLVCTPASCGLGEVCGLLPSGQ--HGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCE 2097
GG V PA C P Q + P + C+AWG H T DG + G
Sbjct: 116 GGECV-HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGS 174
Query: 2098 YLLSAPCHGPPLGAENFTVTVANEHR-GSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD 2156
Y L H P ++F++ V N+ + GS + +R+V+L +++
Sbjct: 175 YTLVGR-HEPE--GQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQ---EIHLAKEVTHG 228
Query: 2157 GVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNY 2216
G+ V LP + S L+G V+V S +LA+DG S V +++ GLCGN
Sbjct: 229 GMRVQLPHVMGSARLQQLAGY-VIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNN 287
Query: 2217 NQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCT------PEQQESFGGPDACGV 2270
N DP DDL GK V E P P T P Q++ G GV
Sbjct: 288 NADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQ--GV 345
Query: 2271 ISATDGPLAP----CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQL 2326
+ L P CH V P + C D CQ G C A+A Y AC AG L
Sbjct: 346 YEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 405
Query: 2327 GEWRRP-DFCPLQCPAHSH-YELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGD 2384
WR C + C + Y C CP SC ++ E AC +GC C G +
Sbjct: 406 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDG 465
Query: 2385 TCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDG 2444
CV +C C G YP PG + C C G
Sbjct: 466 GCVAPAECPCEFHGTLYP------PGSVVKEDCNT-------------------CTCTSG 500
Query: 2445 VQACHATGC-GRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNA 2503
C C C G IH+ T DGR Y +C Y+LA+ F++ L+
Sbjct: 501 KWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAK----SRSSGTFTVTLQNAP 556
Query: 2504 AG---------DLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVL 2554
G + +L + V+L Q V + + +P ++ L
Sbjct: 557 CGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFL 616
Query: 2555 Q--TTKGLRLLFDGDA-HLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETF 2611
+ T G+R+L+D + L + + + GLCG FNGN DDF+ P G S+ + F
Sbjct: 617 RVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLF 676
Query: 2612 GAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSE 2671
G +W+ + G C V L + A Y S +AC L FA C A LSP
Sbjct: 677 GNSWKTLSACSPLVSGSPLDPCDVHL--QAASY-SVQACSVLTGEM--FAPCSAFLSPVP 731
Query: 2672 YFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICT 2731
YF QC D C + + LC +LA Y C+ G+ V C L C A YS C
Sbjct: 732 YFEQCRRDAC--RCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCV 789
Query: 2732 RTCQGSCAALSGLTGC---------TTRCFEGCEC-DDRFLLSQG-VCIPVQDCGCTHNG 2780
C +C L+ C C EGC C D +L +Q +C+P C C G
Sbjct: 790 APCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQG 849
Query: 2781 RYLPVNSSLLTSDCSERCSCSS---SSGLTCQAAGCPPGRV 2818
P S + S C C S AA CP G+V
Sbjct: 850 VDYPPGDSDIPS--LGHCHCKDGVMSCDSRAPAAACPAGQV 888
Score = 161 bits (408), Expect = 8e-39
Identities = 154/588 (26%), Positives = 227/588 (38%), Gaps = 47/588 (7%)
Query: 2416 RCECGPGGHVTCQEGAACGPHE--ECRLEDGV----QACHATGCGR---CLANGGIHYIT 2466
R +C P +C G C +CR + Q + G R C A G H T
Sbjct: 102 RAKCAPSYLFSCFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVET 161
Query: 2467 LDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRL-------LVTVAGQVV 2519
DG Y L G SY L V +P + FSI + + L V Q +
Sbjct: 162 FDGLYYYLSGKGSYTL--VGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEI 219
Query: 2520 SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFR 2579
LA+ +VT G V LP +G R+ ++++ L +DG + + + +
Sbjct: 220 HLAK--EVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELL 277
Query: 2580 GRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAE 2639
G GLCGN N + DD V +G V F +W+ ++ G P CL +
Sbjct: 278 GWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQ 337
Query: 2640 ETAPYES-NEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYT 2698
+ E C L P PF C A +SP + C DLC GD A CR+LA Y
Sbjct: 338 NPGTMQGVYEQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYA 395
Query: 2699 AACQAAGVAVKPWRTD-SFCPLHCPAHSH-YSICTRTCQGSCAALSGLTGCTTRCFEGCE 2756
AC AG ++ WRT C +HC + Y+ C C SC + C +GC
Sbjct: 396 RACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCY 455
Query: 2757 CDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPG 2816
C + + G C+ +C C +G P S++ DC+ C+C+S C A CP
Sbjct: 456 CPNGLIFEDGGCVAPAECPCEFHGTLYP-PGSVVKEDCN-TCTCTSGK-WECSTAVCP-- 510
Query: 2817 RVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYR 2876
AE C ++ + TTFDG R + Y L+ T+
Sbjct: 511 ------AE----------CSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQN 554
Query: 2877 VVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDG 2936
+ ++V + VTLT V + +P + + R
Sbjct: 555 APCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSV 614
Query: 2937 SLLVRQKAGVQVWLGANG-KVAVIVSNDHAGKLCGACGNFDGDQTNDW 2983
L VR GV+V G ++ + V G CG F+G+ +D+
Sbjct: 615 FLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDF 662
Score = 115 bits (287), Expect = 9e-25
Identities = 111/421 (26%), Positives = 162/421 (38%), Gaps = 61/421 (14%)
Query: 729 GISVGDWRSPANCPLSCPANSRYELCGP-------ACPTSCNGAAAPSNCSGR-PCVEGC 780
G+ D R+PA +CPA + C + +C + S R PC+ GC
Sbjct: 870 GVMSCDSRAPA---AACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGC 926
Query: 781 VCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQS 840
C G + G AC C CT++G + PG +V + C C C + Q T S
Sbjct: 927 ACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSP--C-HTCVCQRGSFQCTLHPCAS 983
Query: 841 CPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL 900
TC GD HY +FDG FDF+G C LV S
Sbjct: 984 ----------------------TCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD---- 1017
Query: 901 PAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADG-- 958
+F V+VEN + S + + + + + V DD P D
Sbjct: 1018 VSFSVIVENVNCYSSGMICRKFISINVGNSLI---------VFDDDSGNPSPESFLDDKQ 1068
Query: 959 QVQVFRQGRDAVVR-TDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALR 1017
+V +R G +V +T+ +D V + + L GLCGNF+ +++
Sbjct: 1069 EVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTP 1128
Query: 1018 GGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRE 1077
+ N FG+SW P +P D L+ L ++ +K EC IL F
Sbjct: 1129 ENLELTNPQEFGSSWAAVECP--DTLDPRDMCVLNPL--REPFAKKECSILLSE--VFEI 1182
Query: 1078 CHSKLDPQGAVRDCVYDR--CLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLS 1135
CH +D +C+ D C G C +++ YA C G V WR+ LCP
Sbjct: 1183 CHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYD 1241
Query: 1136 C 1136
C
Sbjct: 1242 C 1242
Score = 98.6 bits (244), Expect = 8e-20
Identities = 82/297 (27%), Positives = 126/297 (42%), Gaps = 27/297 (9%)
Query: 455 CQVVGGKAGCVAESTA-VCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSV 513
C G C A C A GD HY TFDG +D +G C +V+ S+ +FSV
Sbjct: 967 CVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD----VSFSV 1022
Query: 514 EAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQS 573
+N + Y + R + +S+ G V D+ + P S + + V+
Sbjct: 1023 IVENVN------CYSSGMICRKF---ISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTW 1073
Query: 574 GPRAVVELVFGLV-VTYDWDCQLALSLPA--RFQDQVCGLCGNYNGDPADDFLTPDGALA 630
+ F +T WD + + + A ++Q Q+ GLCGN++ ++ TP+
Sbjct: 1074 RVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLEL 1133
Query: 631 PDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDT 690
+ EF SSW + C D C + + C +L L F +CH
Sbjct: 1134 TNPQEFGSSWAAVE----CPDTLDPR-DMCVLNPLREPFAKKECSIL--LSEVFEICHPV 1186
Query: 691 LDPRPFLEQCVYDL--CVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSC 745
+D F C+ D C GG+ C +SAYA C + G++V DWR+P CP C
Sbjct: 1187 VDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1242
Score = 92.4 bits (228), Expect = 6e-18
Identities = 117/502 (23%), Positives = 189/502 (37%), Gaps = 87/502 (17%)
Query: 2355 SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLH----DGRYYPLGEVFYPG 2410
S P+LS EG A + + TCVP+ + C+ +G+ + + +
Sbjct: 2025 SAPALSIVEGLAEALATTTEAN-----TSTTCVPIAEQDCVRHICLEGQLIRVNQSQHC- 2078
Query: 2411 PECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGR 2470
P+ CG G G C P EC AC RC + ++T DG
Sbjct: 2079 PQGAAPPRCGILGLAVRVGGDRCCPLWEC-------AC------RCSIFPDLSFVTFDGS 2125
Query: 2471 VYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRL-----------LVTVAGQVV 2519
L Y+L+Q DE ++ + + +L L + +A QV
Sbjct: 2126 HVALFKEAIYILSQ-----SPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVT 2180
Query: 2520 SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLM---SIPS 2576
++VTVD + V PV+ R+ G ++ T +++ + + L++ S S
Sbjct: 2181 IDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTS 2240
Query: 2577 PFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVET---FGAAWRAPGSSKGCGE------G 2627
+G GLCG +G+ ++D L +GS E F +W+ P S G+
Sbjct: 2241 KAQGH--GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDS 2298
Query: 2628 CGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDK 2687
C C CL + AC + P+ + C+ + ++Y +Q
Sbjct: 2299 CATTDCSPCL--RMVSNRTFSACHRFVPPE---SFCELWIRDTKYVQQP----------- 2342
Query: 2688 AFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTG- 2746
C +L Y A C V ++ WR +CP C + S Y C C+ G+ G
Sbjct: 2343 ---CVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGP 2398
Query: 2747 -----CTTRCFEGCECDDRFLLSQ---GVCIPVQDCGCTHN---GRYLPVNSSLLTSDCS 2795
C EGC C + +L + +CIP C CT + R L + S C
Sbjct: 2399 LDPEHCQV-LGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCC 2457
Query: 2796 ERCSCSSSSGLTCQAAGCPPGR 2817
+ C + + GCP R
Sbjct: 2458 QH-QCQAPDTIVPVDLGCPSPR 2478
Score = 91.3 bits (225), Expect = 1e-17
Identities = 115/456 (25%), Positives = 171/456 (37%), Gaps = 78/456 (17%)
Query: 419 GLAKAIGYATAADCGRTVLSPVEPSCEGMQCAAGQ-----------------RCQV---- 457
GLA+A+ T A+ T + E C C GQ RC +
Sbjct: 2034 GLAEALATTTEANTSTTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLA 2093
Query: 458 --VGGKAGC-VAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVE 514
VGG C + E C D + TFDG + Y + + S D+ L ++
Sbjct: 2094 VRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQ--SPDEMLTVHVLD 2151
Query: 515 AKNEHRGSRRVSYVGLVTVRA--YSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQ 572
K+ + G LV + +H V++ R V VD Q PVS R+
Sbjct: 2152 CKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRK-VTVDLQPVWPPVS--RYGFRIED 2208
Query: 573 SGPRAVVELVFGLVVTYDWDCQLALSLPARFQD-QVCGLCGNYNGDPADDFLTPDGAL-- 629
+G ++ + + + L + ++ Q GLCG +GD A+D DG++
Sbjct: 2209 TGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVG 2268
Query: 630 -APDAVEFASSWKLDDG------DYLCEDGCQN-NCPACTPGQAQHYEGDRLCGMLTKLD 681
A D F SW++ D C +C C R+ T
Sbjct: 2269 GAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCL----------RMVSNRT--- 2315
Query: 682 GPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANC 741
F+ CH + P F E + D V C L+ Y C + + + +WR C
Sbjct: 2316 --FSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCI-EWRRSDYC 2368
Query: 742 PLSCPANSRYELCGPAC--PTSCN----GAAAPSNCSGRPCVEGCVCLPGFV---ASGGA 792
P C ++S Y+ C AC P +C G P +C + EGCVC G +
Sbjct: 2369 PFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHC--QVLGEGCVCSEGTILHRRHSAL 2426
Query: 793 CVPASSCGCT-FQGLQLAPGQEVWADEL---CQRRC 824
C+P + C CT G+ A G E W L CQ +C
Sbjct: 2427 CIPEAKCACTDSMGVPRALG-ETWNSSLSGCCQHQC 2461
Score = 90.1 bits (222), Expect = 3e-17
Identities = 121/509 (23%), Positives = 184/509 (36%), Gaps = 82/509 (16%)
Query: 1216 CQEGGLVSCESSSCGPHEACQPSGGSLG---------CVAVGSSTCQAS--GDPHYTTFD 1264
C EG L+ S P A P G LG C + C+ S D + TFD
Sbjct: 2064 CLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFD 2123
Query: 1265 GRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQ 1324
G +Y+L+Q+ +H N+ N ++ + + +++
Sbjct: 2124 GSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDR 2183
Query: 1325 RQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQ 1384
KVTV+ + PV +I + H ++ +D ++ + + V
Sbjct: 2184 FNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMI-VEASKTSKA 2242
Query: 1385 QMCGLCGNYNGDPKDDFQKPNGSQAGNANE---FGNSWEEVVPDSPCLPPTPCPPGSEDC 1441
Q GLCG +GD +D +GS G A + F +SW+ VP S L D
Sbjct: 2243 QGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQ--VPSS--LTSVGQTRFRPDS 2298
Query: 1442 IPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSIL 1501
+ C P L ++S+ T S+CH+ V P+ + I D +
Sbjct: 2299 CATTDCSPCLR----------MVSNRT--FSACHRFVPPESFCELWIRDTKY----VQQP 2342
Query: 1502 CSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDG 1561
C + YV+ C +E WR +CP C +S Y+ C C P CQDG
Sbjct: 2343 CVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTAC-------EPPKTCQDG 2394
Query: 1562 ------------CAEGCQCDSGFLY---NGQACVPIQQCGCYHN-GV---YYEPEQTVLI 1602
EGC C G + + C+P +C C + GV E + L
Sbjct: 2395 ILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLS 2454
Query: 1603 DNCRQQCTCHAGKGMVCQEHSC---KPGQVCQPSGGILSCVTKDP-------------CH 1646
C+ Q C A +V + C +P + L TKDP C
Sbjct: 2455 GCCQHQ--CQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCE 2512
Query: 1647 GV--TCRPQETCKEQGGQGVCLPNYEATC 1673
G+ TCRP + C P+Y C
Sbjct: 2513 GLAPTCRPGHRLLTHFQEDSCCPSYSCEC 2541
Score = 84.7 bits (208), Expect = 1e-15
Identities = 105/415 (25%), Positives = 157/415 (37%), Gaps = 79/415 (19%)
Query: 2047 PASCGLGEVCGL-LPSGQHGCQPV--STAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAP 2103
P CG + GL + G C P+ C + D +VT DG Y+LS
Sbjct: 2084 PPRCG---ILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS 2140
Query: 2104 -----------CHGPPLGAEN---FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSAR- 2148
C LG N F + + N VT+ +N +T+ +
Sbjct: 2141 PDEMLTVHVLDCKSANLGHLNWPPFCLVMLN------MTHLAHQVTIDRFNRKVTVDLQP 2194
Query: 2149 -WPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRL----RVPA 2203
WP + F+++ H ++ + T S + + + S + + +
Sbjct: 2195 VWPPVSRYG-------FRIEDTGHMYM------ILTPSDIQIQWLHSSGLMIVEASKTSK 2241
Query: 2204 AYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECV-SKPCPSPCTPEQQESF 2262
A LCG+C D A+DL G VGGA+ + S PS T Q F
Sbjct: 2242 AQGHGLCGICDG---DAANDLTLKDGSV----VGGAEDPAPFLDSWQVPSSLTSVGQTRF 2294
Query: 2263 GGPDACGVISAT-------DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATY 2315
PD+C + + + CH VPP + + + D VQ C A+ Y
Sbjct: 2295 R-PDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVY 2349
Query: 2316 VAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSC--PVSCP----SLSAPEGCESAC 2369
VA C + EWRR D+CP C + S Y+ C +C P +C PE C+
Sbjct: 2350 VAMCHKFHVCI-EWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQ-VL 2407
Query: 2370 REGCVCDAGFVL---SGDTCVPVGQCGCLHD-GRYYPLGEVFYPGPE--CERRCE 2418
EGCVC G +L C+P +C C G LGE + C+ +C+
Sbjct: 2408 GEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQ 2462
Score = 78.6 bits (192), Expect = 9e-14
Identities = 119/493 (24%), Positives = 165/493 (33%), Gaps = 111/493 (22%)
Query: 816 ADELCQRRCTCNGATHQVTCRDKQSCPAGE---RCSVQNGLLG---------CYPDRFGT 863
A++ C R G +V Q CP G RC G+LG C P
Sbjct: 2055 AEQDCVRHICLEGQLIRVN--QSQHCPQGAAPPRC----GILGLAVRVGGDRCCPLWECA 2108
Query: 864 CQGS--GDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL----------------PAFRV 905
C+ S D +V+FDG Y+L S + + P V
Sbjct: 2109 CRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLV 2168
Query: 906 LVENEHRGSQTV--SYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVF 963
++ H Q + R V V+ + V V R G + D Y+ +D Q+Q
Sbjct: 2169 MLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRY--GFRIEDTGHMYMILTPSDIQIQWL 2226
Query: 964 RQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGG---G 1020
+V +K + LCG+C +GD A+DL L+ G G
Sbjct: 2227 HSSGLMIVEA---------------SKTSKAQGHGLCGIC---DGDAANDLTLKDGSVVG 2268
Query: 1021 QAANALAFGNSWQEE---TRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRE 1077
A + F +SWQ T G P C D ++ S F
Sbjct: 2269 GAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRT----------FSA 2318
Query: 1078 CHSKLDPQGA----VRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCP 1133
CH + P+ +RD Y + C AL Y A C + WR + CP
Sbjct: 2319 CHRFVPPESFCELWIRDTKYVQ--------QPCVALTVYVAMCHKFHVCIE-WRRSDYCP 2369
Query: 1134 LSCPPHSHYEACSYGC--PLSCGDLPVPGGCGSECH---EGCVCDEGFAL---SGESCLP 1185
C S Y+AC C P +C D + C EGCVC EG L C+P
Sbjct: 2370 FLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIP 2429
Query: 1186 LASCGCV-HQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGC 1244
A C C G G+T+ L C C + P LGC
Sbjct: 2430 EAKCACTDSMGVPRALGETW-------------NSSLSGCCQHQCQAPDTIVPV--DLGC 2474
Query: 1245 VAVGSSTCQASGD 1257
+ +C G+
Sbjct: 2475 PSPRPESCLRFGE 2487
Score = 63.9 bits (154), Expect = 2e-09
Identities = 113/434 (26%), Positives = 158/434 (36%), Gaps = 67/434 (15%)
Query: 1665 CLPNYEATCW--LWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQ 1722
C P +E C ++ D + +FDG Y+L+ + + LT + K+
Sbjct: 2101 CCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS-----PDEMLTVHVLDCKSA 2155
Query: 1723 NRGN---PAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQG 1779
N G+ P V ++ + L ++I + KV V + V PVS RI
Sbjct: 2156 NLGHLNWPPFCLV-MLNMTHLAHQVTIDRFN-RKVTVDLQPVWP--PVSRYGFRIEDTGH 2211
Query: 1780 ASKALLVADFGLQVSYDWNWR-VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTL--- 1835
L +D +Q + V+ + S G GLCG D + ND +G++
Sbjct: 2212 MYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLKDGSVVGG 2269
Query: 1836 ----APSIPIWG--GSWRAPGWDPLCWDECRGS-CPTCPEDRLEQYEGPGFCGPLASGTG 1888
AP + W S + G D C + C C L +
Sbjct: 2270 AEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPC----------------LRMVSN 2313
Query: 1889 GPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGC 1948
F+ CH VPPESF + + D C AL YVA C V IE WR C
Sbjct: 2314 RTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCIE-WRRSDYC 2368
Query: 1949 EITCPENSHYEVCGPPC--PASCPSP--APLTTPAVCEGPCVEGCQCDAGFVL---SADR 2001
C +S Y+ C C P +C PL P C+ EGC C G +L +
Sbjct: 2369 PFLCSSDSTYQACVTACEPPKTCQDGILGPL-DPEHCQ-VLGEGCVCSEGTILHRRHSAL 2426
Query: 2002 CVPLNNGCGCWANGTYHEAGSEFW---ADGTCSQWCRCGP-----GGGSLVCTPASC-GL 2052
C+P C C + A E W G C C+ G P SC
Sbjct: 2427 CIP-EAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRF 2485
Query: 2053 GEVCGLLPSGQHGC 2066
GEV LLP+ C
Sbjct: 2486 GEVALLLPTKDPCC 2499
Score = 32.7 bits (73), Expect = 5.6
Identities = 26/96 (27%), Positives = 33/96 (34%), Gaps = 17/96 (17%)
Query: 2721 CPAHSHYSICT-----------RTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCI 2769
CPA + C+ RTC+ LS C GC C L C
Sbjct: 883 CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLS--VSARGPCLSGCACPQGLLRHGDACF 940
Query: 2770 PVQDCGCTHNGR-YLPVNSSLLTSDCSERCSCSSSS 2804
++C CT G+ Y P + S C C C S
Sbjct: 941 LPEECPCTWKGKEYFP--GDQVMSPC-HTCVCQRGS 973
>gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo
sapiens]
Length = 2134
Score = 241 bits (616), Expect = 6e-63
Identities = 253/1033 (24%), Positives = 399/1033 (38%), Gaps = 158/1033 (15%)
Query: 1091 CVYDRCLLPGQSGPLCDALATYAAACQAAG-ATVHPWRSEE--LCPLS-CPPHSHYEACS 1146
C+ + C ++ CD + + C + G T WRS+ +C CP Y+ C
Sbjct: 714 CIDEYCQTRDKTST-CDTYSELSRLCASDGPGTFESWRSDSDVVCETQRCPEQHIYKECG 772
Query: 1147 YGCPLSCGDLPVPGGCGSECHEGCVCDEGFALS--GES--CLPLASCGCVHQGTYHPPGQ 1202
P +C + V SEC GC C EG+ L GE C+ A C C GT + PG+
Sbjct: 773 PSNPATCSN--VAPFQDSECVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGE 830
Query: 1203 TFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTT 1262
GP C S C CQ+ SC + C C+ G SL TT
Sbjct: 831 V-REGP-CGSQCTCQDAKW-SCTEALCPGR--CKVEGSSL------------------TT 867
Query: 1263 FDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRL 1322
FDG +++F G C ++ +++ E +G+ + N ++ +
Sbjct: 868 FDGVKYNFPGNCHFLAVHN-------EDWSISVELRPCPSGQTGTCLNSVTLLLNSSVPV 920
Query: 1323 EQRQWKV--TVNGVDMKLPVVLANGQIRASQHGSDVV-IETDFGLRVAYDLVYYVR--VT 1377
++ + TV ++ + +I+ S + +ET F +++ +V ++ V+
Sbjct: 921 DKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVS 980
Query: 1378 VPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPG 1437
+P N + GLCG+YN +DDF + F NSWE + CP G
Sbjct: 981 MPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMM----------SCPKG 1030
Query: 1438 S-EDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGG 1496
+ CI +EK+ E CG+L +GPL+SCH +V+P+ ++C C
Sbjct: 1031 NPSSCI-------SIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCEN 1083
Query: 1497 NLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPP 1556
+ LC+ + YV AC ++ WRT C CP ++ C+ C +LS
Sbjct: 1084 SQDCLCTILGNYVKACAEKETYIVGWRT-GLCEHSCPSGLVFKYNVKACNSSCRSLSERD 1142
Query: 1557 Q---CQDGCAEGCQCDSGFLYNGQA-CVPIQQCGCYHNGVYYEPEQTVLIDN----CR-- 1606
+ +D +GC C N + CV QC CY N +P + + ID+ CR
Sbjct: 1143 RSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDG 1202
Query: 1607 ------------QQC--------------------TCHAGKGMVCQEH-SCKPGQVCQPS 1633
Q C TC V E+ CK G C P
Sbjct: 1203 ILLCQIPIDLTLQNCSGGAEYVDCSDPKAQRRTNRTCSTRNIPVFDENLPCKRGCFC-PE 1261
Query: 1634 GGILS----CVTKDPC-----------HGVTCRPQETCKEQGGQGVCLPN-YEATCWLWG 1677
G + + CV + C VT C G C N + C ++G
Sbjct: 1262 GMVRNSKGICVFPNDCPCSFGGREYDEGSVTSVGCNECTCIKGSWSCTQNECQTICHIYG 1321
Query: 1678 DPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTV 1737
+ H +FDG+ + F G C Y C + F + T++ ++ R + V
Sbjct: 1322 EGHVRTFDGKSYSFDGLCQYSFLEDYCGHEN----GTFRILTESVPCCEDGLTCSRKIIV 1377
Query: 1738 AALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDW 1797
A NI + ++ V+ + + S+ +L G+ V +D
Sbjct: 1378 AFQDQNIVLQDGKVTAVK-----STESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDK 1432
Query: 1798 NWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWD 1857
N R+ V L +++G VCGLCGN + + +D ++A +G SW+ C D
Sbjct: 1433 NTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKT---SQECSD 1489
Query: 1858 ECRGSCPTCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGD 1917
+ P C + + C L T F CH V P ++ C+ + C +
Sbjct: 1490 TVAQTFP-CDSNPYCKAWAVRKCEILRDST---FRDCHNKVDPSAYHDVCIEEACACDME 1545
Query: 1918 RDIL--CKALASYVAACQAAGVVIEDWRAQVGCEITCPENS-------HYEVCGPPCPAS 1968
L C A+A Y AC A GV + WR C + C + HYE CG +
Sbjct: 1546 GKYLGFCTAVAMYAEACSAVGVCV-SWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKT 1604
Query: 1969 CPSP-APLTTPAVCEGPCVEGCQCDAGFV-LSADRCVPLNNGCGCWANGTYHEAGSEFWA 2026
C ++ EG C C A ++ + +CV L+ C C+ N G
Sbjct: 1605 CKDQLVGQKFSSLLEG-CYAKCPDSAPYLDENTMKCVSLSE-CSCFYNDVIPAGGV---I 1659
Query: 2027 DGTCSQWCRCGPG 2039
+ C + C C G
Sbjct: 1660 EDNCGRTCYCIAG 1672
Score = 221 bits (563), Expect = 8e-57
Identities = 224/883 (25%), Positives = 339/883 (38%), Gaps = 146/883 (16%)
Query: 452 GQRCQVVGGKAGCV-AESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPA 510
G +C K C A C+ +G TTFDG +Y+ G C + V +ED ++
Sbjct: 837 GSQCTCQDAKWSCTEALCPGRCKVEGSS-LTTFDGVKYNFPGNCHFLAVH--NEDWSISV 893
Query: 511 FSVEAKNEHRGSRRVSYVGL----VTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEG 566
+ G+ S L V V Y + T V N + R
Sbjct: 894 ELRPCPSGQTGTCLNSVTLLLNSSVPVDKYVFNSDGT--------VTNDKIRNQGYYYSD 945
Query: 567 RLRVYQSGPRAV-VELVFG--LVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFL 623
+++++ + + VE F L + QL +S+P GLCG+YN DDF+
Sbjct: 946 KIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFM 1005
Query: 624 TPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGP 683
+ L + FA+SW++ C G N +C + + + +R CG+L GP
Sbjct: 1006 SSQNILEKTSQAFANSWEMMS----CPKG---NPSSCISIEKEKF-AERHCGILLDSSGP 1057
Query: 684 FAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPL 743
A CH ++P+P+ E+C C + LC L Y +AC E + WR+ C
Sbjct: 1058 LASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGL-CEH 1116
Query: 744 SCPANSRYELCGPACPTSCNGAAAPSNCSGRPC------VEGCVCLPGFVASG-GACVPA 796
SCP+ ++ AC +SC + R C V+GC C + G CV
Sbjct: 1117 SCPSGLVFKYNVKACNSSCRSLSERD----RSCDVEDVPVDGCTCPDAMYQNNEGNCVLK 1172
Query: 797 SSCGCTFQGLQLAPGQEVWADE----------LCQRRC-----TCNGATHQVTCRDKQS- 840
S C C + PG+ + D+ LCQ C+G V C D ++
Sbjct: 1173 SQCDCYINDEVMQPGKLIHIDDNKCVCRDGILLCQIPIDLTLQNCSGGAEYVDCSDPKAQ 1232
Query: 841 --------------------------CPAG------------------------------ 844
CP G
Sbjct: 1233 RRTNRTCSTRNIPVFDENLPCKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYDEGSVT 1292
Query: 845 ----ERCSVQNGLLGCYPDRFGT-CQGSGDPHYVSFDGRRFDFMGTCTY-LLVGSCGQNA 898
C+ G C + T C G+ H +FDG+ + F G C Y L CG
Sbjct: 1293 SVGCNECTCIKGSWSCTQNECQTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHEN 1352
Query: 899 ALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADG 958
FR+L E+ ++ +R + V + + ++ G+V + +
Sbjct: 1353 G--TFRILTESVPCCEDGLTCSRKIIVAFQDQNIVLQ---DGKVTAVKSTESKKCELNAN 1407
Query: 959 QVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRG 1018
+ G +++ G+ V +D N R++ + ++ +CGLCGN NGD DD R
Sbjct: 1408 AYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRY 1467
Query: 1019 GGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFREC 1078
A+ AL FGNSW +T C T P DS + + +C IL D FR+C
Sbjct: 1468 SSVASGALEFGNSW--KTSQECSDTVAQTFP-CDSNPYCKAWAVRKCEILRD--STFRDC 1522
Query: 1079 HSKLDPQGAVRDCVYDRCL--LPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSC 1136
H+K+DP C+ + C + G+ C A+A YA AC A G V WR LCP+ C
Sbjct: 1523 HNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCV-SWRKPNLCPVYC 1581
Query: 1137 PPHS-------HYEACSYGCPLSCGDLPVPGGCGSECHEGCV--CDEGFALSGES---CL 1184
++ HYE C +C D V G S EGC C + E+ C+
Sbjct: 1582 DYYNAPGECRWHYEPCGTVTAKTCKDQLV-GQKFSSLLEGCYAKCPDSAPYLDENTMKCV 1640
Query: 1185 PLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESS 1227
L+ C C + P G C C+C G L E++
Sbjct: 1641 SLSECSCFYNDVI-PAGGVI--EDNCGRTCYCIAGQLECSETA 1680
Score = 145 bits (366), Expect = 6e-34
Identities = 138/475 (29%), Positives = 192/475 (40%), Gaps = 68/475 (14%)
Query: 1166 CHEGCVCDEGFALSGES-CLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSC 1224
C GC C EG + + C+ C C G + G GC+ C C +G SC
Sbjct: 1253 CKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYDEGSV--TSVGCNE-CTCIKGSW-SC 1308
Query: 1225 ESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVY-VLAQTCG 1283
+ C + C G+ H TFDG+ + F G C Y L CG
Sbjct: 1309 TQNEC-------------------QTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCG 1349
Query: 1284 TRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVT-VNGVDMKLPVVL 1342
G F +L E+V ++ +R I V + + L+ KVT V + K +
Sbjct: 1350 HENGT--FRILTESVPCCEDGLTCSRKIIVAFQDQNIVLQDG--KVTAVKSTESKKCELN 1405
Query: 1343 ANGQIRASQH--GSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDD 1400
AN S H G ++++ G+ V +D + V + N+ ++CGLCGN NGD KDD
Sbjct: 1406 ANAY---SIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDD 1462
Query: 1401 FQKPNGSQAGNANEFGNSWEEVVPDSPCLPPT-PCPPGSEDCIPSHKCPPELEKKYQKEE 1459
F S A A EFGNSW+ S + T PC D P C +K
Sbjct: 1463 FTTRYSSVASGALEFGNSWKTSQECSDTVAQTFPC-----DSNP--YCKAWAVRK----- 1510
Query: 1460 FCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGG--GNLSILCSNIHAYVSACQAAGG 1517
C +L T CH VDP CI + C G C+ + Y AC A G
Sbjct: 1511 -CEILRDST--FRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGV 1567
Query: 1518 HVEPWRTETFCPMECPPNS-------HYELCADTCSLGCSALSAPPQCQ---DGCAEGCQ 1567
V WR CP+ C + HYE C + C + +GC C
Sbjct: 1568 CVS-WRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQKFSSLLEGCYAKCP 1626
Query: 1568 CDSGFL-YNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQE 1621
+ +L N CV + +C C++N V P V+ DNC + C C AG+ + C E
Sbjct: 1627 DSAPYLDENTMKCVSLSECSCFYNDVI--PAGGVIEDNCGRTCYCIAGQ-LECSE 1678
Score = 144 bits (363), Expect = 1e-33
Identities = 139/532 (26%), Positives = 207/532 (38%), Gaps = 89/532 (16%)
Query: 2369 CREGCVCDAGFVL-SGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTC 2427
C+ GC C G V S CV C C GR Y G V G C EC TC
Sbjct: 1253 CKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYDEGSVTSVG--CN---EC------TC 1301
Query: 2428 QEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCSY-VLAQVC 2486
+G+ EC+ CH G G H T DG+ Y G C Y L C
Sbjct: 1302 IKGSWSCTQNECQT-----ICHIYGEG--------HVRTFDGKSYSFDGLCQYSFLEDYC 1348
Query: 2487 HPKPGDEDFSIVLE-----KNAAGDLQRLLVTVAGQVVSLAQGQQVTVDG-EAVALPVAV 2540
+ G F I+ E ++ ++++V Q + L G+ V E+ +
Sbjct: 1349 GHENGT--FRILTESVPCCEDGLTCSRKIIVAFQDQNIVLQDGKVTAVKSTESKKCELNA 1406
Query: 2541 GRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLP 2600
+ G ++L+ G+ +++D + L + + + G++CGLCGN NG+ DDF
Sbjct: 1407 NAYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTR 1466
Query: 2601 NGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESN--------EACGQ 2652
S AS FG +W+ +S+ C + +T P +SN C
Sbjct: 1467 YSSVASGALEFGNSWK---TSQECSD----------TVAQTFPCDSNPYCKAWAVRKCEI 1513
Query: 2653 LRNPQGPFATCQAVLSPSEYFRQCVYDLCA--QKGDKAFLCRSLAAYTAACQAAGVAVKP 2710
LR+ F C + PS Y C+ + CA +G C ++A Y AC A GV V
Sbjct: 1514 LRD--STFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCVS- 1570
Query: 2711 WRTDSFCPLHCPAHS-------HYSIC----TRTCQGSCAA---LSGLTGCTTRCFEGCE 2756
WR + CP++C ++ HY C +TC+ S L GC +C +
Sbjct: 1571 WRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQKFSSLLEGCYAKCPDSAP 1630
Query: 2757 CDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPG 2816
D + C+ + +C C +N +P ++ +C C C + L C P
Sbjct: 1631 YLDENTMK---CVSLSECSCFYND-VIPA-GGVIEDNCGRTCYCIAGQ-LECSET-APTN 1683
Query: 2817 RVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTS-PGVYELSSRCPG 2867
V T +LS GA +T G S P + SS G
Sbjct: 1684 STFAVS-------TTTATTILSTGAAITLVTGGPSTAASIPAITTSSSETTG 1728
Score = 139 bits (349), Expect = 6e-32
Identities = 107/399 (26%), Positives = 167/399 (41%), Gaps = 34/399 (8%)
Query: 445 EGMQCAAG-QRCQVVGGKAGCVA-ESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVE-L 501
EG + G C + G C E +C G+ H TFDG+ Y G C Y+ +E
Sbjct: 1288 EGSVTSVGCNECTCIKGSWSCTQNECQTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDY 1347
Query: 502 CSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPV 561
C ++ F + ++ ++ + V ++ L G+V V +
Sbjct: 1348 CGHENG--TFRILTESVPCCEDGLTCSRKIIVAFQDQNIVLQDGKVTAVKSTESKK---C 1402
Query: 562 SLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADD 621
L+ ++ G +++ G++V +D + +L++ L + +VCGLCGN NGD DD
Sbjct: 1403 ELNANAYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDD 1462
Query: 622 FLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLD 681
F T ++A A+EF +SWK C D P C R C +L D
Sbjct: 1463 FTTRYSSVASGALEFGNSWKTSQE---CSDTVAQTFP-CDSNPYCKAWAVRKCEILR--D 1516
Query: 682 GPFAVCHDTLDPRPFLEQCVYDLCV--VGGERLSLCRGLSAYAQACLELGISVGDWRSPA 739
F CH+ +DP + + C+ + C + G+ L C ++ YA+AC +G+ V WR P
Sbjct: 1517 STFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCV-SWRKPN 1575
Query: 740 NCPLSC-----PANSR--YELCGPACPTSCNGAAAPSNCSGRPCVEGCVC-----LPGFV 787
CP+ C P R YE CG +C S +EGC P
Sbjct: 1576 LCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQKFSS--LLEGCYAKCPDSAPYLD 1633
Query: 788 ASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTC 826
+ CV S C C + + A G ++ C R C C
Sbjct: 1634 ENTMKCVSLSECSCFYNDVIPAGGV---IEDNCGRTCYC 1669
Score = 136 bits (343), Expect = 3e-31
Identities = 153/599 (25%), Positives = 223/599 (37%), Gaps = 102/599 (17%)
Query: 1861 GSCPTCPEDRLEQYE-GPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRD 1919
G CP E E G C + G F C + +K +D D+
Sbjct: 669 GDCPNAVGKSYEVCEDGIQHCNKII---GTYFEKCGKVAALSNDYKMICIDEYCQTRDKT 725
Query: 1920 ILCKALASYVAACQAAGV-VIEDWRAQ--VGCEIT-CPENSHYEVCGPPCPASCPSPAPL 1975
C + C + G E WR+ V CE CPE Y+ CGP PA+C + AP
Sbjct: 726 STCDTYSELSRLCASDGPGTFESWRSDSDVVCETQRCPEQHIYKECGPSNPATCSNVAPF 785
Query: 1976 TTPAVCEGPCVEGCQCDAGFVLS----ADRCVPLNNGCGCWANGTYHEAGSEFWADGTCS 2031
+ CV GC C G++L +CV L C C ++GT ++ G +G C
Sbjct: 786 Q-----DSECVSGCTCPEGYLLDDIGEKGKCV-LKAECPCESSGTVYQPGEV--REGPCG 837
Query: 2032 QWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFD 2091
C C S CT A C C+ G T DG +++
Sbjct: 838 SQCTCQDAKWS--CTEALC--------------------PGRCKVEGSS-LTTFDGVKYN 874
Query: 2092 FQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGS-QAVSYTRSVTL----------QIYN 2140
F G C +L + E+++++V S Q + SVTL ++N
Sbjct: 875 FPGNCHFLA--------VHNEDWSISVELRPCPSGQTGTCLNSVTLLLNSSVPVDKYVFN 926
Query: 2141 HSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLR 2200
T++ K++ G + + Q+ + ++L V T + L ++L
Sbjct: 927 SDGTVTND---KIRNQGYYYSDKIQIFNASSSYLQ-----VETYFHVKLQIQIVPVMQLY 978
Query: 2201 V--PAAYAASLCGLCGNYNQDPADDL--------KAVGGKPAGWQVGGAQGCGECVSKPC 2250
V P GLCG+YN DD K W++ C K
Sbjct: 979 VSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEM---MSC----PKGN 1031
Query: 2251 PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCP 2310
PS C ++E F CG++ + GPLA CH +V P Y + C C + LC
Sbjct: 1032 PSSCISIEKEKFAERH-CGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCT 1090
Query: 2311 AVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPE---GCES 2367
+ YV AC + W R C CP+ ++ +C SC SLS + E
Sbjct: 1091 ILGNYVKACAEKETYIVGW-RTGLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVED 1149
Query: 2368 ACREGCVC-DAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPEC---ERRCECGPG 2422
+GC C DA + + CV QC C Y EV PG + +C C G
Sbjct: 1150 VPVDGCTCPDAMYQNNEGNCVLKSQCDC------YINDEVMQPGKLIHIDDNKCVCRDG 1202
Score = 131 bits (330), Expect = 9e-30
Identities = 136/590 (23%), Positives = 224/590 (37%), Gaps = 80/590 (13%)
Query: 648 LCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVV 707
+CEDG Q+ C ++E CG + L + + C+ + C
Sbjct: 681 VCEDGIQH----CNKIIGTYFEK---CGKVAALSNDYKMI------------CIDEYCQT 721
Query: 708 GGERLSLCRGLSAYAQACLELGISVGD-WRSPANCPLS---CPANSRYELCGPACPTSCN 763
++ S C S ++ C G + WRS ++ CP Y+ CGP+ P +C+
Sbjct: 722 R-DKTSTCDTYSELSRLCASDGPGTFESWRSDSDVVCETQRCPEQHIYKECGPSNPATCS 780
Query: 764 GAAAPSNCSGRPCVEGCVCLPGF----VASGGACVPASSCGCTFQGLQLAPGQEVWADEL 819
A + CV GC C G+ + G CV + C C G PG+ +
Sbjct: 781 NVAPFQDSE---CVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGEV--REGP 835
Query: 820 CQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRR 879
C +CTC A T + CP RC V+ L +FDG +
Sbjct: 836 CGSQCTCQDAKWSCT---EALCPG--RCKVEGSSL------------------TTFDGVK 872
Query: 880 FDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYP 939
++F G C +L V + ++ ++ + G+ S T + K +
Sbjct: 873 YNFPGNCHFLAVHN--EDWSISVELRPCPSGQTGTCLNSVTLLLNSSVPVDKYVFNSD-- 928
Query: 940 GQVLVDDVLQYLPFQAADGQVQVFRQGRDAV-VRTDF--GLTVTYDWNARVTAKVPSSYA 996
+ +D ++ + +D ++Q+F + V T F L + ++ +P +
Sbjct: 929 -GTVTNDKIRNQGYYYSD-KIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQF 986
Query: 997 EALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVA 1056
GLCG++N DD + AF NSW+ C P C ++
Sbjct: 987 TDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWE---MMSCPKGNPSSCISIE---- 1039
Query: 1057 QQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAAC 1116
++ ++ CGIL D GP CH ++P+ +C C LC L Y AC
Sbjct: 1040 KEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKAC 1099
Query: 1117 QAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPV-PGGCGSE--CHEGCVCD 1173
+ WR+ LC SCP ++ C SC L C E +GC C
Sbjct: 1100 AEKETYIVGWRT-GLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCP 1158
Query: 1174 EGFALSGE-SCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLV 1222
+ + E +C+ + C C PG+ + D+ C C++G L+
Sbjct: 1159 DAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHID---DNKCVCRDGILL 1205
Score = 127 bits (319), Expect = 2e-28
Identities = 124/482 (25%), Positives = 191/482 (39%), Gaps = 87/482 (18%)
Query: 1984 PCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSL 2043
PC GC C G V ++ N C C G ++ GS C++ C C G S
Sbjct: 1252 PCKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYDEGSV--TSVGCNE-CTCIKGSWS- 1307
Query: 2044 VCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEY-LLSA 2102
CT Q+ CQ + C +G+ H T DG + F G C+Y L
Sbjct: 1308 -CT----------------QNECQTI----CHIYGEGHVRTFDGKSYSFDGLCQYSFLED 1346
Query: 2103 PCHGPPLGAENFTVTVANEHRG--SQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFV 2160
C G EN T + E ++ +R + + + ++ L DG
Sbjct: 1347 YC-----GHENGTFRILTESVPCCEDGLTCSRKIIVAFQDQNIVLQ---------DGKVT 1392
Query: 2161 ALPF------QLDSLLHA-HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLC 2213
A+ +L++ ++ H G +++ +G+ + +D ++ + + + + +CGLC
Sbjct: 1393 AVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLC 1452
Query: 2214 GNYNQDPADDLK------AVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDA 2267
GN N D DD A G G +Q C + V++ PC
Sbjct: 1453 GNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQ--TFPCDSNPYCKAWAVRK 1510
Query: 2268 CGVISATDGPLAPCHGLVPPAQYFQGCLLD--ACQVQGHPGGLCPAVATYVAACQAAGAQ 2325
C ++ D CH V P+ Y C+ + AC ++G G C AVA Y AC A G
Sbjct: 1511 CEIL--RDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVC 1568
Query: 2326 LGEWRRPDFCPLQCPAHS-------HYELCGDSCPVSCPS-------LSAPEGCESACRE 2371
+ WR+P+ CP+ C ++ HYE CG +C S EGC + C
Sbjct: 1569 V-SWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQKFSSLLEGCYAKCP- 1626
Query: 2372 GCVCDAGFVLSGDT--CVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQE 2429
D+ L +T CV + +C C ++ P G V C R C C G + C E
Sbjct: 1627 ----DSAPYLDENTMKCVSLSECSCFYND-VIPAGGVI--EDNCGRTCYC-IAGQLECSE 1678
Query: 2430 GA 2431
A
Sbjct: 1679 TA 1680
Score = 126 bits (316), Expect = 4e-28
Identities = 131/545 (24%), Positives = 193/545 (35%), Gaps = 80/545 (14%)
Query: 2294 CLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPD---FCPLQ-CPAHSHYELCG 2349
C+ + CQ + C + C + G E R D C Q CP Y+ CG
Sbjct: 714 CIDEYCQTRDKTS-TCDTYSELSRLCASDGPGTFESWRSDSDVVCETQRCPEQHIYKECG 772
Query: 2350 DSCPVSCPSLSAPEGCESACREGCVCDAGFVLSG----DTCVPVGQCGCLHDGRYYPLGE 2405
S P +C +++ + +S C GC C G++L CV +C C G Y GE
Sbjct: 773 PSNPATCSNVAPFQ--DSECVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGE 830
Query: 2406 VFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGC-GRCLANGGIHY 2464
V R CG +C +D +C C GRC G
Sbjct: 831 V--------REGPCG----------------SQCTCQDAKWSCTEALCPGRCKVEGS-SL 865
Query: 2465 ITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVSLAQG 2524
T DG Y+ G+C ++ +ED+SI +E Q V+L
Sbjct: 866 TTFDGVKYNFPGNCHFLAVH-------NEDWSISVELRPCPSGQ---TGTCLNSVTLLLN 915
Query: 2525 QQVTVDGEAVALPVAVGRVRVTAEG------------RNMVLQTTK----GLRLLFDGDA 2568
V VD V ++ +G + LQ L++
Sbjct: 916 SSVPVDKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASSSYLQVETYFHVKLQIQIVPVM 975
Query: 2569 HLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGC 2628
L +S+P GLCG++N DDF+ + + F +W KG
Sbjct: 976 QLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMSCPKG----- 1030
Query: 2629 GPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKA 2688
P C E+ A CG L + GP A+C +++P Y +C C + +
Sbjct: 1031 NPSSCISIEKEKFA----ERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQD 1086
Query: 2689 FLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGL-TGC 2747
LC L Y AC + WRT C CP+ + + C SC +LS C
Sbjct: 1087 CLCTILGNYVKACAEKETYIVGWRT-GLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSC 1145
Query: 2748 TTR--CFEGCECDD-RFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSS 2804
+GC C D + ++G C+ C C N + + D +C C
Sbjct: 1146 DVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDD--NKCVCRDGI 1203
Query: 2805 GLTCQ 2809
L CQ
Sbjct: 1204 -LLCQ 1207
Score = 113 bits (283), Expect = 2e-24
Identities = 137/599 (22%), Positives = 220/599 (36%), Gaps = 102/599 (17%)
Query: 1459 EFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAG-G 1517
E CG +++ LS+ +K++ CI + C S C C + G G
Sbjct: 698 EKCGKVAA----LSNDYKMI--------CIDEYCQTRDKTST-CDTYSELSRLCASDGPG 744
Query: 1518 HVEPWRTETFCPME---CPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLY 1574
E WR+++ E CP Y+ C + CS ++ P C GC C G+L
Sbjct: 745 TFESWRSDSDVVCETQRCPEQHIYKECGPSNPATCSNVA--PFQDSECVSGCTCPEGYLL 802
Query: 1575 NGQA----CVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEHSCKPGQVC 1630
+ CV +C C +G Y+P + V C QCTC K C E C PG+
Sbjct: 803 DDIGEKGKCVLKAECPCESSGTVYQPGE-VREGPCGSQCTCQDAKWS-CTEALC-PGR-- 857
Query: 1631 QPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFD 1690
CK +G +FDG K++
Sbjct: 858 -------------------------CKVEGSS------------------LTTFDGVKYN 874
Query: 1691 FQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDE 1750
F G C+++ +S + L P + + VT+ L +++ + K
Sbjct: 875 FPGNCHFLAVHNEDWSISVE-LRPCP--------SGQTGTCLNSVTLL-LNSSVPVDKYV 924
Query: 1751 IGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVADF---GLQVSYDWNWRVDVTLPS 1807
N + +D +I + +S L V + LQ+ ++ V++P
Sbjct: 925 FNSDGTVTNDKIRNQGYYYSD-KIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPP 983
Query: 1808 SYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCP 1867
+ GLCG+ + +D + L + + SW C SC +
Sbjct: 984 NQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMS----CPKGNPSSCISIE 1039
Query: 1868 EDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALAS 1927
+++ + CG L + GP +CH V P+ + + C C +D LC L +
Sbjct: 1040 KEKFAERH----CGILLD-SSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGN 1094
Query: 1928 YVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVE 1987
YV AC I WR + CE +CP ++ C +SC S + E V+
Sbjct: 1095 YVKACAEKETYIVGWRTGL-CEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVD 1153
Query: 1988 GCQC-DAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVC 2045
GC C DA + + CV L + C C+ N + G D +C G L+C
Sbjct: 1154 GCTCPDAMYQNNEGNCV-LKSQCDCYINDEVMQPGKLIHIDDN-----KCVCRDGILLC 1206
Score = 61.6 bits (148), Expect = 1e-08
Identities = 52/200 (26%), Positives = 83/200 (41%), Gaps = 33/200 (16%)
Query: 2660 FATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAV-KPWRTDS--F 2716
F C V + S ++ D Q DK C + + + C + G + WR+DS
Sbjct: 697 FEKCGKVAALSNDYKMICIDEYCQTRDKTSTCDTYSELSRLCASDGPGTFESWRSDSDVV 756
Query: 2717 CPLH-CPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLL----SQGVCIPV 2771
C CP Y C + +C+ ++ + C GC C + +LL +G C+
Sbjct: 757 CETQRCPEQHIYKECGPSNPATCSNVAPFQD--SECVSGCTCPEGYLLDDIGEKGKCVLK 814
Query: 2772 QDCGCTHNGR-YLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWA 2830
+C C +G Y P + C +C+C + +C A C PGR C+V+
Sbjct: 815 AECPCESSGTVYQP--GEVREGPCGSQCTCQDAK-WSCTEALC-PGR-CKVE-------- 861
Query: 2831 TRGLCVLSVGANLTTFDGAR 2850
G++LTTFDG +
Sbjct: 862 ---------GSSLTTFDGVK 872
Score = 60.1 bits (144), Expect = 3e-08
Identities = 58/235 (24%), Positives = 97/235 (41%), Gaps = 26/235 (11%)
Query: 2751 CFEGCECDDRFLL-SQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQ 2809
C GC C + + S+G+C+ DC C+ GR S+ + C+E C+C S +C
Sbjct: 1253 CKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYD-EGSVTSVGCNE-CTCIKGSW-SCT 1309
Query: 2810 AAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQ 2869
C +C + E ++ TFDG + Y G +
Sbjct: 1310 QNECQT--ICHIYGEG----------------HVRTFDGKSYSFDGLCQYSFLEDYCGHE 1351
Query: 2870 NTIPWYRVVAE-VQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASV 2928
N +R++ E V C ++ + FQD + L K V E A+
Sbjct: 1352 NGT--FRILTESVPCCEDGLTCSRKIIVAFQDQNIVLQDGKVTAVKSTE-SKKCELNANA 1408
Query: 2929 SVSRTPDGSLLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTNDW 2983
T L+++ + G+ V N +++VI+ + GK+CG CGN +GD +D+
Sbjct: 1409 YSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDF 1463
>gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo
sapiens]
Length = 2134
Score = 241 bits (615), Expect = 8e-63
Identities = 253/1033 (24%), Positives = 399/1033 (38%), Gaps = 158/1033 (15%)
Query: 1091 CVYDRCLLPGQSGPLCDALATYAAACQAAG-ATVHPWRSEE--LCPLS-CPPHSHYEACS 1146
C+ + C ++ CD + + C + G T WRS+ +C CP Y+ C
Sbjct: 714 CIDEYCQTRDKTST-CDTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECG 772
Query: 1147 YGCPLSCGDLPVPGGCGSECHEGCVCDEGFALS--GES--CLPLASCGCVHQGTYHPPGQ 1202
P +C + V SEC GC C EG+ L GE C+ A C C GT + PG+
Sbjct: 773 PSNPATCSN--VAPFQDSECVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGE 830
Query: 1203 TFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTT 1262
GP C S C CQ+ SC + C C+ G SL TT
Sbjct: 831 V-REGP-CGSQCTCQDAKW-SCTEALCPGR--CKVEGSSL------------------TT 867
Query: 1263 FDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRL 1322
FDG +++F G C ++ +++ E +G+ + N ++ +
Sbjct: 868 FDGVKYNFPGNCHFLAVHN-------EDWSISVELRPCPSGQTGTCLNSVTLLLNSSVPV 920
Query: 1323 EQRQWKV--TVNGVDMKLPVVLANGQIRASQHGSDVV-IETDFGLRVAYDLVYYVR--VT 1377
++ + TV ++ + +I+ S + +ET F +++ +V ++ V+
Sbjct: 921 DKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVS 980
Query: 1378 VPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPG 1437
+P N + GLCG+YN +DDF + F NSWE + CP G
Sbjct: 981 MPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMM----------SCPKG 1030
Query: 1438 S-EDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGG 1496
+ CI +EK+ E CG+L +GPL+SCH +V+P+ ++C C
Sbjct: 1031 NPSSCI-------SIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCEN 1083
Query: 1497 NLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPP 1556
+ LC+ + YV AC ++ WRT C CP ++ C+ C +LS
Sbjct: 1084 SQDCLCTILGNYVKACAEKETYIVGWRT-GLCEHSCPSGLVFKYNVKACNSSCRSLSERD 1142
Query: 1557 Q---CQDGCAEGCQCDSGFLYNGQA-CVPIQQCGCYHNGVYYEPEQTVLIDN----CR-- 1606
+ +D +GC C N + CV QC CY N +P + + ID+ CR
Sbjct: 1143 RSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDG 1202
Query: 1607 ------------QQC--------------------TCHAGKGMVCQEH-SCKPGQVCQPS 1633
Q C TC V E+ CK G C P
Sbjct: 1203 ILLCQIPIDLTLQNCSGGAEYVDCSDPKAQRRTNRTCSTRNIPVFDENLPCKRGCFC-PE 1261
Query: 1634 GGILS----CVTKDPC-----------HGVTCRPQETCKEQGGQGVCLPN-YEATCWLWG 1677
G + + CV + C VT C G C N + C ++G
Sbjct: 1262 GMVRNSKGICVFPNDCPCSFGGREYDEGSVTSVGCNECTCIKGSWSCTQNECQTICHIYG 1321
Query: 1678 DPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTV 1737
+ H +FDG+ + F G C Y C + F + T++ ++ R + V
Sbjct: 1322 EGHVRTFDGKSYSFDGLCQYSFLEDYCGHEN----GTFRILTESVPCCEDGLTCSRKIIV 1377
Query: 1738 AALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDW 1797
A NI + ++ V+ + + S+ +L G+ V +D
Sbjct: 1378 AFQDQNIVLQDGKVTAVK-----STESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDK 1432
Query: 1798 NWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWD 1857
N R+ V L +++G VCGLCGN + + +D ++A +G SW+ C D
Sbjct: 1433 NTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKT---SQECSD 1489
Query: 1858 ECRGSCPTCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGD 1917
+ P C + + C L T F CH V P ++ C+ + C +
Sbjct: 1490 TVAQTFP-CDSNPYCKAWAVRKCEILRDST---FRDCHNKVDPSAYHDVCIEEACACDME 1545
Query: 1918 RDIL--CKALASYVAACQAAGVVIEDWRAQVGCEITCPENS-------HYEVCGPPCPAS 1968
L C A+A Y AC A GV + WR C + C + HYE CG +
Sbjct: 1546 GKYLGFCTAVAMYAEACSAVGVCV-SWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKT 1604
Query: 1969 CPSP-APLTTPAVCEGPCVEGCQCDAGFV-LSADRCVPLNNGCGCWANGTYHEAGSEFWA 2026
C ++ EG C C A ++ + +CV L+ C C+ N G
Sbjct: 1605 CKDQLVGQKFSSLLEG-CYAKCPDSAPYLDENTMKCVSLSE-CSCFYNDVIPAGGV---I 1659
Query: 2027 DGTCSQWCRCGPG 2039
+ C + C C G
Sbjct: 1660 EDNCGRTCYCIAG 1672
Score = 221 bits (563), Expect = 8e-57
Identities = 224/883 (25%), Positives = 339/883 (38%), Gaps = 146/883 (16%)
Query: 452 GQRCQVVGGKAGCV-AESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPA 510
G +C K C A C+ +G TTFDG +Y+ G C + V +ED ++
Sbjct: 837 GSQCTCQDAKWSCTEALCPGRCKVEGSS-LTTFDGVKYNFPGNCHFLAVH--NEDWSISV 893
Query: 511 FSVEAKNEHRGSRRVSYVGL----VTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEG 566
+ G+ S L V V Y + T V N + R
Sbjct: 894 ELRPCPSGQTGTCLNSVTLLLNSSVPVDKYVFNSDGT--------VTNDKIRNQGYYYSD 945
Query: 567 RLRVYQSGPRAV-VELVFG--LVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFL 623
+++++ + + VE F L + QL +S+P GLCG+YN DDF+
Sbjct: 946 KIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFM 1005
Query: 624 TPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGP 683
+ L + FA+SW++ C G N +C + + + +R CG+L GP
Sbjct: 1006 SSQNILEKTSQAFANSWEMMS----CPKG---NPSSCISIEKEKF-AERHCGILLDSSGP 1057
Query: 684 FAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPL 743
A CH ++P+P+ E+C C + LC L Y +AC E + WR+ C
Sbjct: 1058 LASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGL-CEH 1116
Query: 744 SCPANSRYELCGPACPTSCNGAAAPSNCSGRPC------VEGCVCLPGFVASG-GACVPA 796
SCP+ ++ AC +SC + R C V+GC C + G CV
Sbjct: 1117 SCPSGLVFKYNVKACNSSCRSLSERD----RSCDVEDVPVDGCTCPDAMYQNNEGNCVLK 1172
Query: 797 SSCGCTFQGLQLAPGQEVWADE----------LCQRRC-----TCNGATHQVTCRDKQS- 840
S C C + PG+ + D+ LCQ C+G V C D ++
Sbjct: 1173 SQCDCYINDEVMQPGKLIHIDDNKCVCRDGILLCQIPIDLTLQNCSGGAEYVDCSDPKAQ 1232
Query: 841 --------------------------CPAG------------------------------ 844
CP G
Sbjct: 1233 RRTNRTCSTRNIPVFDENLPCKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYDEGSVT 1292
Query: 845 ----ERCSVQNGLLGCYPDRFGT-CQGSGDPHYVSFDGRRFDFMGTCTY-LLVGSCGQNA 898
C+ G C + T C G+ H +FDG+ + F G C Y L CG
Sbjct: 1293 SVGCNECTCIKGSWSCTQNECQTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHEN 1352
Query: 899 ALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADG 958
FR+L E+ ++ +R + V + + ++ G+V + +
Sbjct: 1353 G--TFRILTESVPCCEDGLTCSRKIIVAFQDQNIVLQ---DGKVTAVKSTESKKCELNAN 1407
Query: 959 QVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRG 1018
+ G +++ G+ V +D N R++ + ++ +CGLCGN NGD DD R
Sbjct: 1408 AYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRY 1467
Query: 1019 GGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFREC 1078
A+ AL FGNSW +T C T P DS + + +C IL D FR+C
Sbjct: 1468 SSVASGALEFGNSW--KTSQECSDTVAQTFP-CDSNPYCKAWAVRKCEILRD--STFRDC 1522
Query: 1079 HSKLDPQGAVRDCVYDRCL--LPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSC 1136
H+K+DP C+ + C + G+ C A+A YA AC A G V WR LCP+ C
Sbjct: 1523 HNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCV-SWRKPNLCPVYC 1581
Query: 1137 PPHS-------HYEACSYGCPLSCGDLPVPGGCGSECHEGCV--CDEGFALSGES---CL 1184
++ HYE C +C D V G S EGC C + E+ C+
Sbjct: 1582 DYYNAPGECRWHYEPCGTVTAKTCKDQLV-GQKFSSLLEGCYAKCPDSAPYLDENTMKCV 1640
Query: 1185 PLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESS 1227
L+ C C + P G C C+C G L E++
Sbjct: 1641 SLSECSCFYNDVI-PAGGVI--EDNCGRTCYCIAGQLECSETA 1680
Score = 145 bits (366), Expect = 6e-34
Identities = 138/475 (29%), Positives = 192/475 (40%), Gaps = 68/475 (14%)
Query: 1166 CHEGCVCDEGFALSGES-CLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSC 1224
C GC C EG + + C+ C C G + G GC+ C C +G SC
Sbjct: 1253 CKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYDEGSV--TSVGCNE-CTCIKGSW-SC 1308
Query: 1225 ESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVY-VLAQTCG 1283
+ C + C G+ H TFDG+ + F G C Y L CG
Sbjct: 1309 TQNEC-------------------QTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCG 1349
Query: 1284 TRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVT-VNGVDMKLPVVL 1342
G F +L E+V ++ +R I V + + L+ KVT V + K +
Sbjct: 1350 HENGT--FRILTESVPCCEDGLTCSRKIIVAFQDQNIVLQDG--KVTAVKSTESKKCELN 1405
Query: 1343 ANGQIRASQH--GSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDD 1400
AN S H G ++++ G+ V +D + V + N+ ++CGLCGN NGD KDD
Sbjct: 1406 ANAY---SIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDD 1462
Query: 1401 FQKPNGSQAGNANEFGNSWEEVVPDSPCLPPT-PCPPGSEDCIPSHKCPPELEKKYQKEE 1459
F S A A EFGNSW+ S + T PC D P C +K
Sbjct: 1463 FTTRYSSVASGALEFGNSWKTSQECSDTVAQTFPC-----DSNP--YCKAWAVRK----- 1510
Query: 1460 FCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGG--GNLSILCSNIHAYVSACQAAGG 1517
C +L T CH VDP CI + C G C+ + Y AC A G
Sbjct: 1511 -CEILRDST--FRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGV 1567
Query: 1518 HVEPWRTETFCPMECPPNS-------HYELCADTCSLGCSALSAPPQCQ---DGCAEGCQ 1567
V WR CP+ C + HYE C + C + +GC C
Sbjct: 1568 CVS-WRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQKFSSLLEGCYAKCP 1626
Query: 1568 CDSGFL-YNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQE 1621
+ +L N CV + +C C++N V P V+ DNC + C C AG+ + C E
Sbjct: 1627 DSAPYLDENTMKCVSLSECSCFYNDVI--PAGGVIEDNCGRTCYCIAGQ-LECSE 1678
Score = 144 bits (363), Expect = 1e-33
Identities = 139/532 (26%), Positives = 207/532 (38%), Gaps = 89/532 (16%)
Query: 2369 CREGCVCDAGFVL-SGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTC 2427
C+ GC C G V S CV C C GR Y G V G C EC TC
Sbjct: 1253 CKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYDEGSVTSVG--CN---EC------TC 1301
Query: 2428 QEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCSY-VLAQVC 2486
+G+ EC+ CH G G H T DG+ Y G C Y L C
Sbjct: 1302 IKGSWSCTQNECQT-----ICHIYGEG--------HVRTFDGKSYSFDGLCQYSFLEDYC 1348
Query: 2487 HPKPGDEDFSIVLE-----KNAAGDLQRLLVTVAGQVVSLAQGQQVTVDG-EAVALPVAV 2540
+ G F I+ E ++ ++++V Q + L G+ V E+ +
Sbjct: 1349 GHENGT--FRILTESVPCCEDGLTCSRKIIVAFQDQNIVLQDGKVTAVKSTESKKCELNA 1406
Query: 2541 GRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLP 2600
+ G ++L+ G+ +++D + L + + + G++CGLCGN NG+ DDF
Sbjct: 1407 NAYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTR 1466
Query: 2601 NGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESN--------EACGQ 2652
S AS FG +W+ +S+ C + +T P +SN C
Sbjct: 1467 YSSVASGALEFGNSWK---TSQECSD----------TVAQTFPCDSNPYCKAWAVRKCEI 1513
Query: 2653 LRNPQGPFATCQAVLSPSEYFRQCVYDLCA--QKGDKAFLCRSLAAYTAACQAAGVAVKP 2710
LR+ F C + PS Y C+ + CA +G C ++A Y AC A GV V
Sbjct: 1514 LRD--STFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCVS- 1570
Query: 2711 WRTDSFCPLHCPAHS-------HYSIC----TRTCQGSCAA---LSGLTGCTTRCFEGCE 2756
WR + CP++C ++ HY C +TC+ S L GC +C +
Sbjct: 1571 WRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQKFSSLLEGCYAKCPDSAP 1630
Query: 2757 CDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPG 2816
D + C+ + +C C +N +P ++ +C C C + L C P
Sbjct: 1631 YLDENTMK---CVSLSECSCFYND-VIPA-GGVIEDNCGRTCYCIAGQ-LECSET-APTN 1683
Query: 2817 RVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTS-PGVYELSSRCPG 2867
V T +LS GA +T G S P + SS G
Sbjct: 1684 STFAVS-------TTTATTILSTGAAITLVTGGPSTAASIPAITTSSSETTG 1728
Score = 139 bits (349), Expect = 6e-32
Identities = 107/399 (26%), Positives = 167/399 (41%), Gaps = 34/399 (8%)
Query: 445 EGMQCAAG-QRCQVVGGKAGCVA-ESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVE-L 501
EG + G C + G C E +C G+ H TFDG+ Y G C Y+ +E
Sbjct: 1288 EGSVTSVGCNECTCIKGSWSCTQNECQTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDY 1347
Query: 502 CSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPV 561
C ++ F + ++ ++ + V ++ L G+V V +
Sbjct: 1348 CGHENG--TFRILTESVPCCEDGLTCSRKIIVAFQDQNIVLQDGKVTAVKSTESKK---C 1402
Query: 562 SLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADD 621
L+ ++ G +++ G++V +D + +L++ L + +VCGLCGN NGD DD
Sbjct: 1403 ELNANAYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDD 1462
Query: 622 FLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLD 681
F T ++A A+EF +SWK C D P C R C +L D
Sbjct: 1463 FTTRYSSVASGALEFGNSWKTSQE---CSDTVAQTFP-CDSNPYCKAWAVRKCEILR--D 1516
Query: 682 GPFAVCHDTLDPRPFLEQCVYDLCV--VGGERLSLCRGLSAYAQACLELGISVGDWRSPA 739
F CH+ +DP + + C+ + C + G+ L C ++ YA+AC +G+ V WR P
Sbjct: 1517 STFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCV-SWRKPN 1575
Query: 740 NCPLSC-----PANSR--YELCGPACPTSCNGAAAPSNCSGRPCVEGCVC-----LPGFV 787
CP+ C P R YE CG +C S +EGC P
Sbjct: 1576 LCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQKFSS--LLEGCYAKCPDSAPYLD 1633
Query: 788 ASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTC 826
+ CV S C C + + A G ++ C R C C
Sbjct: 1634 ENTMKCVSLSECSCFYNDVIPAGGV---IEDNCGRTCYC 1669
Score = 134 bits (336), Expect = 2e-30
Identities = 152/599 (25%), Positives = 222/599 (37%), Gaps = 102/599 (17%)
Query: 1861 GSCPTCPEDRLEQYE-GPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRD 1919
G CP E E G C + G F C + +K +D D+
Sbjct: 669 GDCPNAVGKSYEVCEDGIQHCNKII---GTYFEKCGKVAALSNDYKMICIDEYCQTRDKT 725
Query: 1920 ILCKALASYVAACQAAGV-VIEDWRAQ--VGCEIT-CPENSHYEVCGPPCPASCPSPAPL 1975
C + C + G E WR+ V C CPE Y+ CGP PA+C + AP
Sbjct: 726 STCDTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECGPSNPATCSNVAPF 785
Query: 1976 TTPAVCEGPCVEGCQCDAGFVLS----ADRCVPLNNGCGCWANGTYHEAGSEFWADGTCS 2031
+ CV GC C G++L +CV L C C ++GT ++ G +G C
Sbjct: 786 Q-----DSECVSGCTCPEGYLLDDIGEKGKCV-LKAECPCESSGTVYQPGEV--REGPCG 837
Query: 2032 QWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFD 2091
C C S CT A C C+ G T DG +++
Sbjct: 838 SQCTCQDAKWS--CTEALC--------------------PGRCKVEGSS-LTTFDGVKYN 874
Query: 2092 FQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGS-QAVSYTRSVTL----------QIYN 2140
F G C +L + E+++++V S Q + SVTL ++N
Sbjct: 875 FPGNCHFLA--------VHNEDWSISVELRPCPSGQTGTCLNSVTLLLNSSVPVDKYVFN 926
Query: 2141 HSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLR 2200
T++ K++ G + + Q+ + ++L V T + L ++L
Sbjct: 927 SDGTVTND---KIRNQGYYYSDKIQIFNASSSYLQ-----VETYFHVKLQIQIVPVMQLY 978
Query: 2201 V--PAAYAASLCGLCGNYNQDPADDL--------KAVGGKPAGWQVGGAQGCGECVSKPC 2250
V P GLCG+YN DD K W++ C K
Sbjct: 979 VSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEM---MSC----PKGN 1031
Query: 2251 PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCP 2310
PS C ++E F CG++ + GPLA CH +V P Y + C C + LC
Sbjct: 1032 PSSCISIEKEKFAERH-CGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCT 1090
Query: 2311 AVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPE---GCES 2367
+ YV AC + W R C CP+ ++ +C SC SLS + E
Sbjct: 1091 ILGNYVKACAEKETYIVGW-RTGLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVED 1149
Query: 2368 ACREGCVC-DAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPEC---ERRCECGPG 2422
+GC C DA + + CV QC C Y EV PG + +C C G
Sbjct: 1150 VPVDGCTCPDAMYQNNEGNCVLKSQCDC------YINDEVMQPGKLIHIDDNKCVCRDG 1202
Score = 131 bits (330), Expect = 9e-30
Identities = 136/590 (23%), Positives = 224/590 (37%), Gaps = 80/590 (13%)
Query: 648 LCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVV 707
+CEDG Q+ C ++E CG + L + + C+ + C
Sbjct: 681 VCEDGIQH----CNKIIGTYFEK---CGKVAALSNDYKMI------------CIDEYCQT 721
Query: 708 GGERLSLCRGLSAYAQACLELGISVGD-WRSPANCPLS---CPANSRYELCGPACPTSCN 763
++ S C S ++ C G + WRS ++ CP Y+ CGP+ P +C+
Sbjct: 722 R-DKTSTCDTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECGPSNPATCS 780
Query: 764 GAAAPSNCSGRPCVEGCVCLPGF----VASGGACVPASSCGCTFQGLQLAPGQEVWADEL 819
A + CV GC C G+ + G CV + C C G PG+ +
Sbjct: 781 NVAPFQDSE---CVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGEV--REGP 835
Query: 820 CQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRR 879
C +CTC A T + CP RC V+ L +FDG +
Sbjct: 836 CGSQCTCQDAKWSCT---EALCPG--RCKVEGSSL------------------TTFDGVK 872
Query: 880 FDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYP 939
++F G C +L V + ++ ++ + G+ S T + K +
Sbjct: 873 YNFPGNCHFLAVHN--EDWSISVELRPCPSGQTGTCLNSVTLLLNSSVPVDKYVFNSD-- 928
Query: 940 GQVLVDDVLQYLPFQAADGQVQVFRQGRDAV-VRTDF--GLTVTYDWNARVTAKVPSSYA 996
+ +D ++ + +D ++Q+F + V T F L + ++ +P +
Sbjct: 929 -GTVTNDKIRNQGYYYSD-KIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQF 986
Query: 997 EALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVA 1056
GLCG++N DD + AF NSW+ C P C ++
Sbjct: 987 TDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWE---MMSCPKGNPSSCISIE---- 1039
Query: 1057 QQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAAC 1116
++ ++ CGIL D GP CH ++P+ +C C LC L Y AC
Sbjct: 1040 KEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKAC 1099
Query: 1117 QAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPV-PGGCGSE--CHEGCVCD 1173
+ WR+ LC SCP ++ C SC L C E +GC C
Sbjct: 1100 AEKETYIVGWRT-GLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCP 1158
Query: 1174 EGFALSGE-SCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLV 1222
+ + E +C+ + C C PG+ + D+ C C++G L+
Sbjct: 1159 DAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHID---DNKCVCRDGILL 1205
Score = 127 bits (319), Expect = 2e-28
Identities = 124/482 (25%), Positives = 191/482 (39%), Gaps = 87/482 (18%)
Query: 1984 PCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSL 2043
PC GC C G V ++ N C C G ++ GS C++ C C G S
Sbjct: 1252 PCKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYDEGSV--TSVGCNE-CTCIKGSWS- 1307
Query: 2044 VCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEY-LLSA 2102
CT Q+ CQ + C +G+ H T DG + F G C+Y L
Sbjct: 1308 -CT----------------QNECQTI----CHIYGEGHVRTFDGKSYSFDGLCQYSFLED 1346
Query: 2103 PCHGPPLGAENFTVTVANEHRG--SQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFV 2160
C G EN T + E ++ +R + + + ++ L DG
Sbjct: 1347 YC-----GHENGTFRILTESVPCCEDGLTCSRKIIVAFQDQNIVLQ---------DGKVT 1392
Query: 2161 ALPF------QLDSLLHA-HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLC 2213
A+ +L++ ++ H G +++ +G+ + +D ++ + + + + +CGLC
Sbjct: 1393 AVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLC 1452
Query: 2214 GNYNQDPADDLK------AVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDA 2267
GN N D DD A G G +Q C + V++ PC
Sbjct: 1453 GNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQ--TFPCDSNPYCKAWAVRK 1510
Query: 2268 CGVISATDGPLAPCHGLVPPAQYFQGCLLD--ACQVQGHPGGLCPAVATYVAACQAAGAQ 2325
C ++ D CH V P+ Y C+ + AC ++G G C AVA Y AC A G
Sbjct: 1511 CEIL--RDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVC 1568
Query: 2326 LGEWRRPDFCPLQCPAHS-------HYELCGDSCPVSCPS-------LSAPEGCESACRE 2371
+ WR+P+ CP+ C ++ HYE CG +C S EGC + C
Sbjct: 1569 V-SWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQKFSSLLEGCYAKCP- 1626
Query: 2372 GCVCDAGFVLSGDT--CVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQE 2429
D+ L +T CV + +C C ++ P G V C R C C G + C E
Sbjct: 1627 ----DSAPYLDENTMKCVSLSECSCFYND-VIPAGGVI--EDNCGRTCYC-IAGQLECSE 1678
Query: 2430 GA 2431
A
Sbjct: 1679 TA 1680
Score = 125 bits (315), Expect = 5e-28
Identities = 131/545 (24%), Positives = 193/545 (35%), Gaps = 80/545 (14%)
Query: 2294 CLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPD---FCPLQ-CPAHSHYELCG 2349
C+ + CQ + C + C + G E R D C Q CP Y+ CG
Sbjct: 714 CIDEYCQTRDKTS-TCDTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECG 772
Query: 2350 DSCPVSCPSLSAPEGCESACREGCVCDAGFVLSG----DTCVPVGQCGCLHDGRYYPLGE 2405
S P +C +++ + +S C GC C G++L CV +C C G Y GE
Sbjct: 773 PSNPATCSNVAPFQ--DSECVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGE 830
Query: 2406 VFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGC-GRCLANGGIHY 2464
V R CG +C +D +C C GRC G
Sbjct: 831 V--------REGPCG----------------SQCTCQDAKWSCTEALCPGRCKVEGS-SL 865
Query: 2465 ITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVSLAQG 2524
T DG Y+ G+C ++ +ED+SI +E Q V+L
Sbjct: 866 TTFDGVKYNFPGNCHFLAVH-------NEDWSISVELRPCPSGQ---TGTCLNSVTLLLN 915
Query: 2525 QQVTVDGEAVALPVAVGRVRVTAEG------------RNMVLQTTK----GLRLLFDGDA 2568
V VD V ++ +G + LQ L++
Sbjct: 916 SSVPVDKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASSSYLQVETYFHVKLQIQIVPVM 975
Query: 2569 HLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGC 2628
L +S+P GLCG++N DDF+ + + F +W KG
Sbjct: 976 QLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMSCPKG----- 1030
Query: 2629 GPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKA 2688
P C E+ A CG L + GP A+C +++P Y +C C + +
Sbjct: 1031 NPSSCISIEKEKFA----ERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQD 1086
Query: 2689 FLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGL-TGC 2747
LC L Y AC + WRT C CP+ + + C SC +LS C
Sbjct: 1087 CLCTILGNYVKACAEKETYIVGWRT-GLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSC 1145
Query: 2748 TTR--CFEGCECDD-RFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSS 2804
+GC C D + ++G C+ C C N + + D +C C
Sbjct: 1146 DVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDD--NKCVCRDGI 1203
Query: 2805 GLTCQ 2809
L CQ
Sbjct: 1204 -LLCQ 1207
Score = 112 bits (281), Expect = 4e-24
Identities = 137/599 (22%), Positives = 221/599 (36%), Gaps = 102/599 (17%)
Query: 1459 EFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAG-G 1517
E CG +++ LS+ +K++ CI + C S C C + G G
Sbjct: 698 EKCGKVAA----LSNDYKMI--------CIDEYCQTRDKTST-CDTYSELSRLCASDGPG 744
Query: 1518 HVEPWRTET--FCPME-CPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLY 1574
E WR+++ C + CP Y+ C + CS ++ P C GC C G+L
Sbjct: 745 TFESWRSDSDVVCGTQRCPEQHIYKECGPSNPATCSNVA--PFQDSECVSGCTCPEGYLL 802
Query: 1575 NGQA----CVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEHSCKPGQVC 1630
+ CV +C C +G Y+P + V C QCTC K C E C PG+
Sbjct: 803 DDIGEKGKCVLKAECPCESSGTVYQPGE-VREGPCGSQCTCQDAKWS-CTEALC-PGR-- 857
Query: 1631 QPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFD 1690
CK +G +FDG K++
Sbjct: 858 -------------------------CKVEGSS------------------LTTFDGVKYN 874
Query: 1691 FQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDE 1750
F G C+++ +S + L P + + VT+ L +++ + K
Sbjct: 875 FPGNCHFLAVHNEDWSISVE-LRPCP--------SGQTGTCLNSVTLL-LNSSVPVDKYV 924
Query: 1751 IGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVADF---GLQVSYDWNWRVDVTLPS 1807
N + +D +I + +S L V + LQ+ ++ V++P
Sbjct: 925 FNSDGTVTNDKIRNQGYYYSD-KIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPP 983
Query: 1808 SYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCP 1867
+ GLCG+ + +D + L + + SW C SC +
Sbjct: 984 NQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMS----CPKGNPSSCISIE 1039
Query: 1868 EDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALAS 1927
+++ + CG L + GP +CH V P+ + + C C +D LC L +
Sbjct: 1040 KEKFAERH----CGILLD-SSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGN 1094
Query: 1928 YVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVE 1987
YV AC I WR + CE +CP ++ C +SC S + E V+
Sbjct: 1095 YVKACAEKETYIVGWRTGL-CEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVD 1153
Query: 1988 GCQC-DAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVC 2045
GC C DA + + CV L + C C+ N + G D +C G L+C
Sbjct: 1154 GCTCPDAMYQNNEGNCV-LKSQCDCYINDEVMQPGKLIHIDDN-----KCVCRDGILLC 1206
Score = 61.2 bits (147), Expect = 1e-08
Identities = 52/200 (26%), Positives = 83/200 (41%), Gaps = 33/200 (16%)
Query: 2660 FATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAV-KPWRTDS--F 2716
F C V + S ++ D Q DK C + + + C + G + WR+DS
Sbjct: 697 FEKCGKVAALSNDYKMICIDEYCQTRDKTSTCDTYSELSRLCASDGPGTFESWRSDSDVV 756
Query: 2717 CPLH-CPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLL----SQGVCIPV 2771
C CP Y C + +C+ ++ + C GC C + +LL +G C+
Sbjct: 757 CGTQRCPEQHIYKECGPSNPATCSNVAPFQD--SECVSGCTCPEGYLLDDIGEKGKCVLK 814
Query: 2772 QDCGCTHNGR-YLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWA 2830
+C C +G Y P + C +C+C + +C A C PGR C+V+
Sbjct: 815 AECPCESSGTVYQP--GEVREGPCGSQCTCQDAK-WSCTEALC-PGR-CKVE-------- 861
Query: 2831 TRGLCVLSVGANLTTFDGAR 2850
G++LTTFDG +
Sbjct: 862 ---------GSSLTTFDGVK 872
Score = 60.1 bits (144), Expect = 3e-08
Identities = 58/235 (24%), Positives = 97/235 (41%), Gaps = 26/235 (11%)
Query: 2751 CFEGCECDDRFLL-SQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQ 2809
C GC C + + S+G+C+ DC C+ GR S+ + C+E C+C S +C
Sbjct: 1253 CKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYD-EGSVTSVGCNE-CTCIKGSW-SCT 1309
Query: 2810 AAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQ 2869
C +C + E ++ TFDG + Y G +
Sbjct: 1310 QNECQT--ICHIYGEG----------------HVRTFDGKSYSFDGLCQYSFLEDYCGHE 1351
Query: 2870 NTIPWYRVVAE-VQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASV 2928
N +R++ E V C ++ + FQD + L K V E A+
Sbjct: 1352 NGT--FRILTESVPCCEDGLTCSRKIIVAFQDQNIVLQDGKVTAVKSTE-SKKCELNANA 1408
Query: 2929 SVSRTPDGSLLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTNDW 2983
T L+++ + G+ V N +++VI+ + GK+CG CGN +GD +D+
Sbjct: 1409 YSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDF 1463
>gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]
Length = 2639
Score = 227 bits (578), Expect = 2e-58
Identities = 219/805 (27%), Positives = 312/805 (38%), Gaps = 133/805 (16%)
Query: 1329 VTVNGVDMKLPVVLANGQI-RASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMC 1387
V +N + + LP V A+ + R S + V + L+V V + VT+ Q+
Sbjct: 367 VLLNELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQ 426
Query: 1388 GLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKC 1447
GLCGN+NG DDF+ +G F N+W+ L P C
Sbjct: 427 GLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKLDWLDDP-----------C 475
Query: 1448 PPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHA 1507
+E E +C LL P CH VDP K C +D C N LC+ + +
Sbjct: 476 SLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSS 535
Query: 1508 YVSACQAAGGHVEPWRTETFCPME---CPPNSHYELCADTCSLGCSALS-APPQCQDGCA 1563
Y AC A G + WR E C + CP + + TC C +LS A C +G A
Sbjct: 536 YARACTAKGVMLWGWR-EHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFA 594
Query: 1564 --EGCQC-DSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGK----- 1615
+GC C D FL CVP+ +C CYH G+Y E V+ ++C C G+
Sbjct: 595 PVDGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQE--ERCVCRDGRLHCRQ 652
Query: 1616 -----------------------------GMVCQ-------EHSCKPGQVCQPSG----G 1635
+ CQ C G VC P G G
Sbjct: 653 IRLIGQSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVC-PDGLMDDG 711
Query: 1636 ILSCVTKDPC----------HGVTCRPQ-ETCKEQGGQGVCLPNY-EATCWLWGDPHYHS 1683
CV + C G + TC + G+ VC TC ++G HY +
Sbjct: 712 RGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYGSGHYIT 771
Query: 1684 FDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTN 1743
FDG+ +DF G C+YV C S+ G F++ T+N G V+ + + + T
Sbjct: 772 FDGKYYDFDGHCSYVAVQDYCGQNSSLG--SFSIITENVPCGTTGVTCSKAIKIFMGRTE 829
Query: 1744 IS--------IHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSY 1795
+ I +DE V V G+ V + ++ G+ V +
Sbjct: 830 LKLEDKHRVVIQRDEGHHVAYTTREV----------GQYLVVESST--------GIIVIW 871
Query: 1796 DWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLC 1855
D V + L SY G VCGLCGN D NND + + S +G SW+ P C
Sbjct: 872 DKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEA---PTC 928
Query: 1856 WDECRGSCPTCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDVCM-- 1913
D P C + + C L S F+ CH+ V P+ F++ CV D C
Sbjct: 929 PDVSTNPEP-CSLNPHRRSWAEKQCSILKSSV---FSICHSKVDPKPFYEACVHDSCSCD 984
Query: 1914 GGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENS-------HYEVCGPPCP 1966
GGD + C A+ASY C G + WR C I C + HYE CG
Sbjct: 985 TGGDCECFCSAVASYAQECTKEGACV-FWRTPDLCPIFCDYYNPPHECEWHYEPCGNRSF 1043
Query: 1967 ASCPSPAPL---TTPAVCEGPCVEGCQCDAG-FVLSADRCVPLNNGCGCWANGTYHEAGS 2022
+C + + + + EG C C D + +CV + CGC+ T++ G+
Sbjct: 1044 ETCRTINGIHSNISVSYLEG-CYPRCPKDRPIYEEDLKKCVTADK-CGCYVEDTHYPPGA 1101
Query: 2023 EFWADGTCSQWCRCGPGGGSLVCTP 2047
+ TC C C +VC P
Sbjct: 1102 SVPTEETCKS-CVC-TNSSQVVCRP 1124
Score = 205 bits (522), Expect = 5e-52
Identities = 181/720 (25%), Positives = 278/720 (38%), Gaps = 144/720 (20%)
Query: 2211 GLCGNYNQDPADDLKAVGGKPAGWQVGGA---QGCGECVSKP--CPSPCTPEQQESFGGP 2265
GLCGN+N DD K G G A + C K PC+ + +
Sbjct: 427 GLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKLDWLDDPCSLNIESANYAE 486
Query: 2266 DACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQ 2325
C ++ T+ P CH V PA+Y++ C D C Q + LC A+++Y AC A G
Sbjct: 487 HWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGVM 546
Query: 2326 LGEWRRPDFCPL---QCPAHSHYELCGDSCPVSCPSLSAPEGCESACRE------GCVC- 2375
L WR C CP + +C +C SLS +S C E GC C
Sbjct: 547 LWGWRE-HVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSE---ADSHCLEGFAPVDGCGCP 602
Query: 2376 DAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPG------------- 2422
D F+ CVP+ +C C H G Y G+V E RC C G
Sbjct: 603 DHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVV---RQEERCVCRDGRLHCRQIRLIGQS 659
Query: 2423 ---------------------GHVTCQEGAACGPHEEC---------RLEDGVQAC---- 2448
++CQ AA H EC ++DG C
Sbjct: 660 CTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDGLMDDGRGGCVVEK 719
Query: 2449 ----------HATG------CGRCLANGGI------------------HYITLDGRVYDL 2474
+++G C C G HYIT DG+ YD
Sbjct: 720 ECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDF 779
Query: 2475 HGSCSYVLAQ-VCHPKPGDEDFSIVLEKNAAGDL-----QRLLVTVAGQVVSLAQGQQVT 2528
G CSYV Q C FSI+ E G + + + + + L +V
Sbjct: 780 DGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVV 839
Query: 2529 V---DGEAVALPVAVGRVRVTAE-GRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCG 2584
+ +G VA T E G+ +V++++ G+ +++D + + + ++G +CG
Sbjct: 840 IQRDEGHHVAY--------TTREVGQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCG 891
Query: 2585 LCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPY 2644
LCGNF+ ++DF + SS FG +W+ + P C
Sbjct: 892 LCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTCPDVSTNPEP-----CSLNPHRRS 946
Query: 2645 ESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCA--QKGDKAFLCRSLAAYTAACQ 2702
+ + C L++ F+ C + + P ++ CV+D C+ GD C ++A+Y C
Sbjct: 947 WAEKQCSILKS--SVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECT 1004
Query: 2703 AAGVAVKPWRTDSFCPLHC----PAHS---HYSICTRTCQGSCAALSGL-TGCTTRCFEG 2754
G V WRT CP+ C P H HY C +C ++G+ + + EG
Sbjct: 1005 KEGACVF-WRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEG 1063
Query: 2755 C--EC-DDRFLLSQGV--CIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQ 2809
C C DR + + + C+ CGC + P +S+ T + + C C++SS + C+
Sbjct: 1064 CYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGASVPTEETCKSCVCTNSSQVVCR 1123
Score = 180 bits (456), Expect = 2e-44
Identities = 137/466 (29%), Positives = 206/466 (44%), Gaps = 57/466 (12%)
Query: 776 CVEGCVCLPGFVASG-GACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVT 834
CV GCVC G + G G CV C C + G ++ D CN T
Sbjct: 697 CVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVD--------CN------T 742
Query: 835 CRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGS- 893
C +C G Q C+ GTC G HY++FDG+ +DF G C+Y+ V
Sbjct: 743 C----TCKRGRWVCTQ---AVCH----GTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDY 791
Query: 894 CGQNAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPF 953
CGQN++L +F ++ EN G+ V+ ++A+++ ++ + ++ V+ D ++ +
Sbjct: 792 CGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHR-VVIQRDEGHHVAY 850
Query: 954 QAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADD 1013
+ G+ VV + G+ V +D V K+ SY +CGLCGNF+ +D
Sbjct: 851 TTRE-------VGQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNND 903
Query: 1014 LALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKG 1073
R ++ L FGNSW+E +T P C ++ ++ +C IL
Sbjct: 904 FTTRDHMVVSSELDFGNSWKEAPTCPDVSTNPEPCSLNPH---RRSWAEKQCSIL--KSS 958
Query: 1074 PFRECHSKLDPQGAVRDCVYDRCLLP--GQSGPLCDALATYAAACQAAGATVHPWRSEEL 1131
F CHSK+DP+ CV+D C G C A+A+YA C GA V WR+ +L
Sbjct: 959 VFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACVF-WRTPDL 1017
Query: 1132 CPLSC----PPHS---HYEACSYGCPLSCGDL-PVPGGCGSECHEGCV--CDEGFALSGE 1181
CP+ C PPH HYE C +C + + EGC C + + E
Sbjct: 1018 CPIFCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEE 1077
Query: 1182 ---SCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSC 1224
C+ CGC + T++PPG + C S C C V C
Sbjct: 1078 DLKKCVTADKCGCYVEDTHYPPGASVPTEETCKS-CVCTNSSQVVC 1122
Score = 176 bits (447), Expect = 2e-43
Identities = 173/675 (25%), Positives = 248/675 (36%), Gaps = 105/675 (15%)
Query: 1079 HSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCP- 1137
H+ LD +G C G D + C +H R L SC
Sbjct: 604 HTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEERCVCRDGRLH-CRQIRLIGQSCTA 662
Query: 1138 PHSHYE-------ACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGES-CLPLASC 1189
P H + A S LSC L G +EC GCVC +G G C+ C
Sbjct: 663 PKIHMDCSNLTALATSKPRALSCQTLAA-GYYHTECVSGCVCPDGLMDDGRGGCVVEKEC 721
Query: 1190 GCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGS 1249
CVH + G C++ C C+ G V + AV
Sbjct: 722 PCVHNNDLYSSGAKIKVD--CNT-CTCKRGRWVCTQ--------------------AVCH 758
Query: 1250 STCQASGDPHYTTFDGRRFDFMGTCVYVLAQT-CGTRPGLHRFAVLQENVAWGNGRVSVT 1308
TC G HY TFDG+ +DF G C YV Q CG L F+++ ENV G V+ +
Sbjct: 759 GTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVTCS 818
Query: 1309 RVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAY 1368
+ I + + L+LE + V D V ++ G +V+E+ G+ V +
Sbjct: 819 KAIKIFMGRTELKLEDKHRVVIQR--DEGHHVAYTTREV-----GQYLVVESSTGIIVIW 871
Query: 1369 DLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPC 1428
D V + + +Y +CGLCGN++ +DF + + +FGNSW+E P P
Sbjct: 872 DKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKE-APTCPD 930
Query: 1429 LPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCI 1488
+ P P C ++ E+ C +L S S CH VDP+ + C+
Sbjct: 931 VSTNPEP-----------CSLNPHRRSWAEKQCSILKSSV--FSICHSKVDPKPFYEACV 977
Query: 1489 FDLCL--GGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMEC----PPNS---HYE 1539
D C GG+ CS + +Y C G V WRT CP+ C PP+ HYE
Sbjct: 978 HDSCSCDTGGDCECFCSAVASYAQECTKEGACVF-WRTPDLCPIFCDYYNPPHECEWHYE 1036
Query: 1540 LCADTCSLGCSALSA-----PPQCQDGCAEGCQCDSGFLYNG-QACVPIQQCGCYHNGVY 1593
C + C ++ +GC C D + CV +CGCY +
Sbjct: 1037 PCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTH 1096
Query: 1594 YEPEQTVLIDNCRQQCTCHAGKGMVCQEHSCK-----------PGQVCQPSGGI-----L 1637
Y P +V + + C C +VC+ K ++C P+G + +
Sbjct: 1097 YPPGASVPTEETCKSCVCTNSSQVVCRPEEGKILNQTQDGAFCYWEICGPNGTVEKHFNI 1156
Query: 1638 SCVTKDPCHGVTCR-----------PQETCKEQGGQGVCLPNYEATCWLWGD------PH 1680
+T P T T L C LW D P
Sbjct: 1157 CSITTRPSTLTTFTTITLPTTPTTFTTTTTTTTPTSSTVLSTTPKLCCLWSDWINEDHPS 1216
Query: 1681 YHSFDGRKFDFQGTC 1695
S DG + F G C
Sbjct: 1217 SGSDDGDRETFDGVC 1231
Score = 160 bits (404), Expect = 2e-38
Identities = 118/404 (29%), Positives = 178/404 (44%), Gaps = 39/404 (9%)
Query: 455 CQVVGGKAGCV-AESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVE-LCSEDDTLPAFS 512
C G+ C A C G HY TFDG+ YD G CSY V+ C ++ +L +FS
Sbjct: 743 CTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFS 802
Query: 513 VEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQ 572
+ +N G+ V+ S ++ + G L D + R+ + EG Y
Sbjct: 803 IITENVPCGTTGVTC---------SKAIKIFMGRTELKLED--KHRVVIQRDEGHHVAYT 851
Query: 573 S---GPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGAL 629
+ G VVE G++V +D + + L ++ VCGLCGN++ +DF T D +
Sbjct: 852 TREVGQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMV 911
Query: 630 APDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHD 689
++F +SWK C D N P C+ + ++ C +L F++CH
Sbjct: 912 VSSELDFGNSWKEAP---TCPDVSTNPEP-CSLNPHRRSWAEKQCSILK--SSVFSICHS 965
Query: 690 TLDPRPFLEQCVYDLCV--VGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSC-- 745
+DP+PF E CV+D C GG+ C +++YAQ C + G V WR+P CP+ C
Sbjct: 966 KVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACV-FWRTPDLCPIFCDY 1024
Query: 746 -----PANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCV--C---LPGFVASGGACVP 795
YE CG +C + +EGC C P + CV
Sbjct: 1025 YNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVT 1084
Query: 796 ASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQ 839
A CGC + PG V +E C + C C ++ QV CR ++
Sbjct: 1085 ADKCGCYVEDTHYPPGASVPTEETC-KSCVCTNSS-QVVCRPEE 1126
Score = 139 bits (350), Expect = 4e-32
Identities = 121/484 (25%), Positives = 191/484 (39%), Gaps = 76/484 (15%)
Query: 1985 CVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLV 2044
CV GC C G + + C C N + +G++ D C+ C C G V
Sbjct: 697 CVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVD--CNT-CTCKRG--RWV 751
Query: 2045 CTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPC 2104
CT A C HG C +G HY+T DG +DF G C Y+
Sbjct: 752 CTQAVC-------------HGT-------CSIYGSGHYITFDGKYYDFDGHCSYVAVQDY 791
Query: 2105 HGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD-GVFVALP 2163
G +F++ N G+ V+ ++++ + + L L + +Q D G VA
Sbjct: 792 CGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYT 851
Query: 2164 FQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADD 2223
G +VV +++G+ + +D + V +++ +Y ++CGLCGN++ +D
Sbjct: 852 --------TREVGQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNND 903
Query: 2224 LKAVGGKPAGWQVGGAQGCGECVSKP----CPSPCTPEQQESFGGPDACGVISATDGPLA 2279
++ E + P P PC+ C ++ ++ +
Sbjct: 904 FTTRDHMVVSSELDFGNSWKEAPTCPDVSTNPEPCSLNPHRRSWAEKQCSILKSS--VFS 961
Query: 2280 PCHGLVPPAQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPL 2337
CH V P +++ C+ D+C G C AVA+Y C GA + WR PD CP+
Sbjct: 962 ICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACV-FWRTPDLCPI 1020
Query: 2338 QC----PAHS---HYELCGDSCPVSCP---------SLSAPEGCESAC-REGCVCDAGFV 2380
C P H HYE CG+ +C S+S EGC C ++ + +
Sbjct: 1021 FCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDL- 1079
Query: 2381 LSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTC-----------QE 2429
CV +CGC + +YP G P E + C C V C Q+
Sbjct: 1080 ---KKCVTADKCGCYVEDTHYPPG-ASVPTEETCKSCVCTNSSQVVCRPEEGKILNQTQD 1135
Query: 2430 GAAC 2433
GA C
Sbjct: 1136 GAFC 1139
Score = 138 bits (348), Expect = 7e-32
Identities = 126/429 (29%), Positives = 188/429 (43%), Gaps = 37/429 (8%)
Query: 449 CAAGQRCQVVGGKAGCVA--ESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDD 506
C+ G + V GC E C GDPHY TFDG Y G C+Y +VE S
Sbjct: 1916 CSNGLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEIS--P 1973
Query: 507 TLPAFSVEAKNEH-RGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSE 565
++ F V N H + +VS + VR + V + + + V Q +R V+L
Sbjct: 1974 SVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPY 2033
Query: 566 GR--LRVYQSGPRAVVEL-VFGLVVTYDWDCQLALSLP-ARFQDQVCGLCGNYNGDPADD 621
+ L VYQSG VV++ G++V+Y+ ++ LP RF + G CG +DD
Sbjct: 2034 KKYGLEVYQSGINYVVDIPELGVLVSYN-GLSFSVRLPYHRFGNNTKGQCGTCTNTTSDD 2092
Query: 622 FLTPDGALAPDAVEFASSWKLDDGD--YLCEDGCQNNCPACT-PGQAQ---HYE--GDRL 673
+ P G + + A W ++D + PA T PG + H + L
Sbjct: 2093 CILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPL 2152
Query: 674 CGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVG 733
C ++ D FA CH + P+ + + CV+D C + G L C L AYA C + I +
Sbjct: 2153 CQLIK--DSLFAQCHALVPPQHYYDACVFDSCFMPGSSLE-CASLQAYAALCAQQNICL- 2208
Query: 734 DWRSPAN--CPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFV-ASG 790
DWR+ + C + CP++ Y+ CGPA +C +++ N VEGC C G + +
Sbjct: 2209 DWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQN--NTVLVEGCFCPEGTMNYAP 2266
Query: 791 GACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQ 850
G V +CGC G P + E + C C + C+ K RCS Q
Sbjct: 2267 GFDVCVKTCGCV--GPDNVPREFGEHFEFDCKNCVCLEGGSGIICQPK-------RCS-Q 2316
Query: 851 NGLLGCYPD 859
+ C D
Sbjct: 2317 KPVTHCVED 2325
Score = 135 bits (339), Expect = 8e-31
Identities = 127/510 (24%), Positives = 194/510 (38%), Gaps = 114/510 (22%)
Query: 2570 LLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCG 2629
L +++ +G++ GLCGNFNG DDF +G ++ F W+A S C +
Sbjct: 413 LFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSS---CHDKLD 469
Query: 2630 PQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAF 2689
P L E+A Y + C L+ + PF C + + P+EY+++C YD C + ++
Sbjct: 470 WLDDPCSLNIESANY-AEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDC 528
Query: 2690 LCRSLAAYTAACQAAGVAVKPWRTDSFCPL---HCPAHSHYSICTRTCQGSCAALSGLTG 2746
LC +L++Y AC A GV + WR + C CP + TCQ +C +LS
Sbjct: 529 LCAALSSYARACTAKGVMLWGWR-EHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADS 587
Query: 2747 CTTRCF---EGCECDDR-FLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSC-- 2800
F +GC C D FL +G C+P+ C C H G YL ++ + ERC C
Sbjct: 588 HCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQE--ERCVCRD 645
Query: 2801 --------------------------------SSSSGLTCQ--AAG-----CPPGRVC-- 2819
S L+CQ AAG C G VC
Sbjct: 646 GRLHCRQIRLIGQSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPD 705
Query: 2820 -----------------------------EVKAEARNCWATRG--LCVLSVGANLTTFDG 2848
++K + C RG +C +V + G
Sbjct: 706 GLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYG 765
Query: 2849 ARGATTSPG-VYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVGQVHIFFQD---GMVT 2904
+ T G Y+ C VA C G+ ++G I ++ G
Sbjct: 766 SGHYITFDGKYYDFDGHC----------SYVAVQDYC-GQNSSLGSFSIITENVPCGTTG 814
Query: 2905 LTPNKGVWVNGLRVDLPAEKLASVSVSRTPDGS-----------LLVRQKAGVQVWLGAN 2953
+T +K + + R +L E V + R L+V G+ V
Sbjct: 815 VTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYTTREVGQYLVVESSTGIIVIWDKR 874
Query: 2954 GKVAVIVSNDHAGKLCGACGNFDGDQTNDW 2983
V + ++ + G +CG CGNFD ND+
Sbjct: 875 TTVFIKLAPSYKGTVCGLCGNFDHRSNNDF 904
Score = 129 bits (323), Expect = 6e-29
Identities = 124/453 (27%), Positives = 171/453 (37%), Gaps = 58/453 (12%)
Query: 1652 PQETCKEQGGQGVCLPNYEATCWLW---------GDPHYHSFDGRKFDFQGTCNYVLATT 1702
P TC G Q V + + + CW W GDPHY +FDG + +QG C YVL
Sbjct: 1912 PMPTCSN-GLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEE 1970
Query: 1703 GCPGVSTQGLTPFTV-TTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGV 1761
P V G+ N P VR T L + + + V+V VN
Sbjct: 1971 ISPSVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQ---VQVQVNRQ 2027
Query: 1762 LTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYH---GAVCGLCG 1818
ALP G G + + + + G+ VSY+ V LP YH G CG
Sbjct: 2028 AVALPYK-KYGLEVYQSGINYVVDIPELGVLVSYN-GLSFSVRLP--YHRFGNNTKGQCG 2083
Query: 1819 NMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCP---TCPEDRLEQYE 1875
++D + P+G + + W L D + CP + +
Sbjct: 2084 TCTNTTSDDCILPSGEIVSNCEAAADQW-------LVNDPSKPHCPHSSSTTKRPAVTVP 2136
Query: 1876 GPGFCGPLASGTGGP---------FTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALA 1926
G G P T P F CHA VPP+ ++ CV D C G + C +L
Sbjct: 2137 GGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSCFMPGS-SLECASLQ 2195
Query: 1927 SYVAACQAAGVVIEDWRAQV--GCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGP 1984
+Y A C + + DWR C + CP + Y+ CGP +C S + V
Sbjct: 2196 AYAALCAQQNICL-DWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQNNTV---- 2250
Query: 1985 CVEGCQCDAG---FVLSADRCVPLNNGCGC-WANGTYHEAGSEFWADGTCSQWCRCGPGG 2040
VEGC C G + D CV CGC + E G F D C C C GG
Sbjct: 2251 LVEGCFCPEGTMNYAPGFDVCV---KTCGCVGPDNVPREFGEHFEFD--CKN-CVCLEGG 2304
Query: 2041 GSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAE 2073
++C P C V + G + V+ A+
Sbjct: 2305 SGIICQPKRCSQKPVTHCVEDGTYLATEVNPAD 2337
Score = 128 bits (322), Expect = 7e-29
Identities = 127/447 (28%), Positives = 178/447 (39%), Gaps = 51/447 (11%)
Query: 1252 CQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWG-NGRVSVTRV 1310
C GDPHY TFDG + + G C YVL + P + F V +N N +VS R
Sbjct: 1941 CTGWGDPHYVTFDGLYYSYQGNCTYVLVEEIS--PSVDNFGVYIDNYHCDPNDKVSCPRT 1998
Query: 1311 I-----TVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIE-TDFGL 1364
+ T +V T+ + Q +V VN + LP + Q G + V++ + G+
Sbjct: 1999 LIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALP--YKKYGLEVYQSGINYVVDIPELGV 2056
Query: 1365 RVAYD-LVYYVRVTVP--GNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEE 1421
V+Y+ L + VR+ GN + CG C N DD P+G N + W
Sbjct: 2057 LVSYNGLSFSVRLPYHRFGNNTKGQCGTCTN---TTSDDCILPSGEIVSNCEAAADQWLV 2113
Query: 1422 VVPDSPCLP--------PTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSS 1473
P P P P PG P C P C L+ +
Sbjct: 2114 NDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTP--------SPLCQLIKDSL--FAQ 2163
Query: 1474 CHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETF--CPME 1531
CH LV PQ C+FD C G+ S+ C+++ AY + C A WR T C +E
Sbjct: 2164 CHALVPPQHYYDACVFDSCFMPGS-SLECASLQAYAALC-AQQNICLDWRNHTHGACLVE 2221
Query: 1532 CPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFL-YNGQACVPIQQCGCY-H 1589
CP + Y+ C C + S+ Q EGC C G + Y V ++ CGC
Sbjct: 2222 CPSHREYQACGPAEEPTCKS-SSSQQNNTVLVEGCFCPEGTMNYAPGFDVCVKTCGCVGP 2280
Query: 1590 NGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEHSC--KPGQVCQPSGGILSCVTK--DPC 1645
+ V E + D C+ G G++CQ C KP C G L+ D C
Sbjct: 2281 DNVPREFGEHFEFD-CKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTC 2339
Query: 1646 HGVTCRPQET--CKEQGGQGVCLPNYE 1670
+T T CKE+ VC +E
Sbjct: 2340 CNITVCKCNTSLCKEK--PSVCPLGFE 2364
Score = 126 bits (317), Expect = 3e-28
Identities = 92/266 (34%), Positives = 123/266 (46%), Gaps = 31/266 (11%)
Query: 594 QLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKL-----DDGDYL 648
QL ++L Q QV GLCGN+NG DDF T G + FA++WK D D+L
Sbjct: 412 QLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKLDWL 471
Query: 649 CEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVG 708
+D C N + A+H+ C +L K + PF CH +DP + ++C YD C
Sbjct: 472 -DDPCSLNIESAN--YAEHW-----CSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQ 523
Query: 709 GERLSLCRGLSAYAQACLELGISVGDWRSPANCPL---SCPANSRYELCGPACPTSCNG- 764
LC LS+YA+AC G+ + WR C SCP + + C +C
Sbjct: 524 NNEDCLCAALSSYARACTAKGVMLWGWREHV-CNKDVGSCPNSQVFLYNLTTCQQTCRSL 582
Query: 765 AAAPSNC-SGRPCVEGCVCLP-GFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQR 822
+ A S+C G V+GC C F+ G CVP + C C +GL L G V E
Sbjct: 583 SEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQE---E 639
Query: 823 RCTC-NGATHQVTCRD----KQSCPA 843
RC C +G H CR QSC A
Sbjct: 640 RCVCRDGRLH---CRQIRLIGQSCTA 662
Score = 125 bits (314), Expect = 6e-28
Identities = 113/425 (26%), Positives = 166/425 (39%), Gaps = 42/425 (9%)
Query: 2416 RCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCG-RCLANGGIHYITLDGRVYDL 2474
+ EC P TC G + R+ED C C C G HY+T DG Y
Sbjct: 1905 KVECEPPPMPTCSNGL-----QPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSY 1959
Query: 2475 HGSCSYVLAQVCHPKPGDEDFSIVLEK-----NAAGDLQRLLV-------TVAGQVVSLA 2522
G+C+YVL + P ++F + ++ N R L+ + V +
Sbjct: 1960 QGNCTYVLVE--EISPSVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMP 2017
Query: 2523 QGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTK-GLRLLFDGDAHLLMSIPSP---F 2578
QV V+ +AVALP + V G N V+ + G+ + ++G L S+ P F
Sbjct: 2018 MQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVLVSYNG---LSFSVRLPYHRF 2074
Query: 2579 RGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSK-GCGEGCGPQGCPVCL 2637
G CG SDD +LP+G S+ E W SK C P
Sbjct: 2075 GNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVT 2134
Query: 2638 AE---ETAPYES---NEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLC 2691
+T P++ + C +++ FA C A++ P Y+ CV+D C G + C
Sbjct: 2135 VPGGGKTTPHKDCTPSPLCQLIKD--SLFAQCHALVPPQHYYDACVFDSCFMPG-SSLEC 2191
Query: 2692 RSLAAYTAACQAAGVAVKPWR--TDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTT 2749
SL AY A C + + WR T C + CP+H Y C + +C + S T
Sbjct: 2192 ASLQAYAALCAQQNICL-DWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQN-NT 2249
Query: 2750 RCFEGCECDDRFL-LSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTC 2808
EGC C + + + G + V+ CGC DC SG+ C
Sbjct: 2250 VLVEGCFCPEGTMNYAPGFDVCVKTCGCVGPDNVPREFGEHFEFDCKNCVCLEGGSGIIC 2309
Query: 2809 QAAGC 2813
Q C
Sbjct: 2310 QPKRC 2314
Score = 119 bits (297), Expect = 6e-26
Identities = 121/456 (26%), Positives = 178/456 (39%), Gaps = 59/456 (12%)
Query: 825 TCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMG 884
TC+ V D C C CY C G GDPHYV+FDG + + G
Sbjct: 1915 TCSNGLQPVRVEDPDGCCWHWECD-------CY------CTGWGDPHYVTFDGLYYSYQG 1961
Query: 885 TCTYLLVGSCGQNAALPAFRVLVENEH---RGSQTVSYTRAVRVEARGVKVAVRREYPGQ 941
CTY+LV + ++ F V ++N H + T VR E + V + P Q
Sbjct: 1962 NCTYVLVEEI--SPSVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQ 2019
Query: 942 VLVDDVLQYLPFQAADGQVQVFRQGRDAVVR-TDFGLTVTYDWNARVTAKVP-SSYAEAL 999
V V Q + ++V++ G + VV + G+ V+Y+ + ++P +
Sbjct: 2020 VQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVLVSYN-GLSFSVRLPYHRFGNNT 2078
Query: 1000 CGLCGNFNGDPADDLALRGGGQAANALAFGNSW--QEETRPGC----------GATEPG- 1046
G CG +DD L G +N A + W + ++P C T PG
Sbjct: 2079 KGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGG 2138
Query: 1047 --DCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGP 1104
P D + C ++ D F +CH+ + PQ CV+D C +PG S
Sbjct: 2139 GKTTPHKDCTPSPL------CQLIKD--SLFAQCHALVPPQHYYDACVFDSCFMPGSSLE 2190
Query: 1105 LCDALATYAAACQAAGATVHPWRSEE--LCPLSCPPHSHYEACSYGCPLSCGDLPVPGGC 1162
C +L YAA C + WR+ C + CP H Y+AC +C
Sbjct: 2191 -CASLQAYAALCAQQNICL-DWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQN- 2247
Query: 1163 GSECHEGCVCDEG---FALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEG 1219
+ EGC C EG +A + C + +CGCV G + P + C C EG
Sbjct: 2248 NTVLVEGCFCPEGTMNYAPGFDVC--VKTCGCV--GPDNVPREFGEHFEFDCKNCVCLEG 2303
Query: 1220 GL-VSCESSSCG--PHEACQPSGGSLGCVAVGSSTC 1252
G + C+ C P C G L + TC
Sbjct: 2304 GSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTC 2339
Score = 117 bits (294), Expect = 1e-25
Identities = 119/428 (27%), Positives = 183/428 (42%), Gaps = 56/428 (13%)
Query: 2059 LPSGQHGCQPVSTAE-------------CQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCH 2105
+P+ +G QPV + C WGDPHYVT DG + +QG C Y+L
Sbjct: 1913 MPTCSNGLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEIS 1972
Query: 2106 GPPLGAENFTVTVANEH-RGSQAVSYTRSVTLQIYNHSLTLSA----RWPRKLQVDGVFV 2160
+NF V + N H + VS R++ ++ + + ++QV+ V
Sbjct: 1973 P---SVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAV 2029
Query: 2161 ALPFQLDSLLHAHLSGADVVVTTTS-GLSLAFDGDSFVRLRVP-AAYAASLCGLCGNYNQ 2218
ALP++ L + SG + VV G+ ++++G SF +R+P + + G CG
Sbjct: 2030 ALPYKKYG-LEVYQSGINYVVDIPELGVLVSYNGLSF-SVRLPYHRFGNNTKGQCGTCTN 2087
Query: 2219 DPADDLKAVGGK-PAGWQVGGAQGCGECVSKP-CPSPCTPEQQESF---GGPDACGVISA 2273
+DD G+ + + Q SKP CP + ++ + GG
Sbjct: 2088 TTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDC 2147
Query: 2274 TDGPL---------APCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGA 2324
T PL A CH LVPP Y+ C+ D+C + G C ++ Y A C
Sbjct: 2148 TPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSCFMPG-SSLECASLQAYAALCAQQNI 2206
Query: 2325 QLGEWRRPDF--CPLQCPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAG---F 2379
L +WR C ++CP+H Y+ CG + +C S S+ + + EGC C G +
Sbjct: 2207 CL-DWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQN-NTVLVEGCFCPEGTMNY 2264
Query: 2380 VLSGDTCVPVGQCGCL-HDGRYYPLGEVFYPGPECERRCECGPGGH-VTCQ-EGAACGPH 2436
D CV CGC+ D GE F +C + C C GG + CQ + + P
Sbjct: 2265 APGFDVCVKT--CGCVGPDNVPREFGEHF--EFDC-KNCVCLEGGSGIICQPKRCSQKPV 2319
Query: 2437 EECRLEDG 2444
C +EDG
Sbjct: 2320 THC-VEDG 2326
Score = 107 bits (266), Expect = 2e-22
Identities = 89/352 (25%), Positives = 139/352 (39%), Gaps = 34/352 (9%)
Query: 444 CEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCS 503
C + A G Q G VC G+ HY TFDG + G C Y C
Sbjct: 12 CLALSLAGGSELQTEGRTRN---HGHNVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCR 68
Query: 504 EDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEV----GFVLVDNQRSRL 559
+ F+V K + + V + + ++ LTR V + L
Sbjct: 69 --GSYKEFAVHLKRGPGQAEAPAGVESILLTIKDDTIYLTRHLAVLNGAVVSTPHYSPGL 126
Query: 560 PVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPA 619
+ S+ +VY GL + ++ + L L L +F++ CGLCG+YNG +
Sbjct: 127 LIEKSDAYTKVYSRA---------GLTLMWNREDALMLELDTKFRNHTCGLCGDYNGLQS 177
Query: 620 DDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPA-CTPGQAQHYEGDRLCGMLT 678
DG L +EF + K++ D +CED + PA C+ +A+ C L
Sbjct: 178 YSEFLSDGVLF-SPLEFGNMQKINQPDVVCEDPEEEVAPASCSEHRAE-------CERLL 229
Query: 679 KLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSP 738
+ FA C D + P+L C D C G +C ++ +++ C G G+WR+
Sbjct: 230 TAEA-FADCQDLVPLEPYLRACQQDRCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTA 288
Query: 739 AN-----CPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPG 785
+ +CP N Y G C +C+ S C ++GC C G
Sbjct: 289 TSAVSPGASKTCPGNLVYLESGSPCMDTCSHLEVSSLCEEHR-MDGCFCPEG 339
Score = 104 bits (259), Expect = 2e-21
Identities = 84/319 (26%), Positives = 129/319 (40%), Gaps = 30/319 (9%)
Query: 2074 CQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRS 2133
C WG+ HY T DG F F G C+Y ++ C G + F V + ++A + S
Sbjct: 37 CSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRG---SYKEFAVHLKRGPGQAEAPAGVES 93
Query: 2134 VTLQIYNHSLTLSARWPRKLQV-DGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFD 2192
+ L I + ++ L+ R L V +G V+ P LL S A V + +GL+L ++
Sbjct: 94 ILLTIKDDTIYLT----RHLAVLNGAVVSTPHYSPGLL-IEKSDAYTKVYSRAGLTLMWN 148
Query: 2193 GDSFVRLRVPAAYAASLCGLCGNYNQ-DPADDLKAVGGKPAGWQVGGAQG-------CGE 2244
+ + L + + CGLCG+YN + + G + + G Q C +
Sbjct: 149 REDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLEFGNMQKINQPDVVCED 208
Query: 2245 CVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGH 2304
+ P+ C+ + E C + + A C LVP Y + C D C+ G
Sbjct: 209 PEEEVAPASCSEHRAE-------CERLLTAEA-FADCQDLVPLEPYLRACQQDRCRCPGG 260
Query: 2305 PGGLCPAVATYVAACQAAGAQLGEWRRPDF-----CPLQCPAHSHYELCGDSCPVSCPSL 2359
+C VA + C AG + G WR CP + Y G C +C L
Sbjct: 261 DTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTCSHL 320
Query: 2360 SAPEGCESACREGCVCDAG 2378
CE +GC C G
Sbjct: 321 EVSSLCEEHRMDGCFCPEG 339
Score = 102 bits (254), Expect = 6e-21
Identities = 75/235 (31%), Positives = 97/235 (41%), Gaps = 27/235 (11%)
Query: 1001 GLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQ 1060
GLCGNFNG DD G A F N+W+ ++ C LD + ++
Sbjct: 427 GLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQS--SCH----DKLDWLDDPCSLNIE 480
Query: 1061 SKNE----CGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAAC 1116
S N C +L + PF CHS +DP + C YD C LC AL++YA AC
Sbjct: 481 SANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARAC 540
Query: 1117 QAAGATVHPWRSEELCPL---SCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHE----- 1168
A G + WR E +C SCP + C +C L S C E
Sbjct: 541 TAKGVMLWGWR-EHVCNKDVGSCPNSQVFLYNLTTCQQTCRSL---SEADSHCLEGFAPV 596
Query: 1169 -GCVC-DEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGL 1221
GC C D F C+PLA C C H+G Y G + C C++G L
Sbjct: 597 DGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQ---EERCVCRDGRL 648
Score = 98.6 bits (244), Expect = 8e-20
Identities = 108/394 (27%), Positives = 156/394 (39%), Gaps = 41/394 (10%)
Query: 1734 VVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVA---DFG 1790
VV +A N+ + K + V +N + LP A SV + +S ++V+
Sbjct: 348 VVLLADKKKNVVVFKSDGS---VLLNELQVNLPHVTAS--FSVFRPSSYHIMVSMAIGVR 402
Query: 1791 LQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPG 1850
LQV ++ VTL + G V GLCGN + +D +G + + + +W+A
Sbjct: 403 LQVQLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQS 462
Query: 1851 WDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLD 1910
C D+ C + +C L T PF CH+ V P ++K C D
Sbjct: 463 ---SCHDKLDWLDDPCSLNIESANYAEHWCS-LLKKTETPFGRCHSAVDPAEYYKRCKYD 518
Query: 1911 VCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEI---TCPENSHYEVCGPPCPA 1967
C + D LC AL+SY AC A GV++ WR V C +CP + + C
Sbjct: 519 TCNCQNNEDCLCAALSSYARACTAKGVMLWGWREHV-CNKDVGSCPNSQVFLYNLTTCQQ 577
Query: 1968 SCPSPAPLTTPAVCEGPCVEGCQC-DAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWA 2026
+C S + + + V+GC C D F+ RCVPL C C+ G Y EAG
Sbjct: 578 TCRSLSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAK-CSCYHRGLYLEAG----- 631
Query: 2027 DGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVS--------TAECQAWG 2078
D Q RC G L C +G+ C P C ++ CQ
Sbjct: 632 DVVVRQEERCVCRDGRLHCRQIRL-IGQSC-TAPKIHMDCSNLTALATSKPRALSCQTLA 689
Query: 2079 DPHY--------VTLDGHRFDFQGTCEYLLSAPC 2104
+Y V DG D +G C PC
Sbjct: 690 AGYYHTECVSGCVCPDGLMDDGRGGCVVEKECPC 723
Score = 98.2 bits (243), Expect = 1e-19
Identities = 80/317 (25%), Positives = 134/317 (42%), Gaps = 28/317 (8%)
Query: 2456 CLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKN-----AAGDLQRL 2510
C G HY T DG V+ G C Y A C + ++F++ L++ A ++ +
Sbjct: 37 CSTWGNFHYKTFDGDVFRFPGLCDYNFASDC--RGSYKEFAVHLKRGPGQAEAPAGVESI 94
Query: 2511 LVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHL 2570
L+T+ + L + V ++G V+ P + + + + GL L+++ + L
Sbjct: 95 LLTIKDDTIYLTRHLAV-LNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLTLMWNREDAL 153
Query: 2571 LMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGP 2630
++ + + FR CGLCG++NG S L +G S +E FG + C + P
Sbjct: 154 MLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLE-FGNMQKINQPDVVCED---P 209
Query: 2631 QGCPVCLAEETAPYESNE---ACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDK 2687
+ EE AP +E C +L + FA CQ ++ Y R C D C G
Sbjct: 210 E-------EEVAPASCSEHRAECERLLTAEA-FADCQDLVPLEPYLRACQQDRCRCPGGD 261
Query: 2688 AFLCRSLAAYTAACQAAGVAVKPWRTDSF-----CPLHCPAHSHYSICTRTCQGSCAALS 2742
+C ++A ++ C AG WRT + CP + Y C +C+ L
Sbjct: 262 TCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTCSHLE 321
Query: 2743 GLTGCTTRCFEGCECDD 2759
+ C +GC C +
Sbjct: 322 VSSLCEEHRMDGCFCPE 338
Score = 86.7 bits (213), Expect = 3e-16
Identities = 86/330 (26%), Positives = 128/330 (38%), Gaps = 35/330 (10%)
Query: 1673 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYV 1732
C WG+ HY +FDG F F G C+Y A + C G F V K A + V
Sbjct: 37 CSTWGNFHYKTFDGDVFRFPGLCDYNFA-SDCRG----SYKEFAVHLKRGPGQAEAPAGV 91
Query: 1733 RVVTVAALGTNISIHKDEIGKVR--VCVNGVLTALPVSVADGRISVAQGASKALLVADFG 1790
+ ++I D I R +NG + + P I + +K A G
Sbjct: 92 ESIL-------LTIKDDTIYLTRHLAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRA--G 142
Query: 1791 LQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPG 1850
L + ++ + + L + + CGLCG+ + + + +G L + +G +
Sbjct: 143 LTLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLE-FGNMQKINQ 201
Query: 1851 WDPLCWDECRGSCP-TCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVL 1909
D +C D P +C E R E C L T F C VP E + + C
Sbjct: 202 PDVVCEDPEEEVAPASCSEHRAE-------CERLL--TAEAFADCQDLVPLEPYLRACQQ 252
Query: 1910 DVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV-----GCEITCPENSHYEVCGPP 1964
D C G +C +A + C AG +WR G TCP N Y G P
Sbjct: 253 DRCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSP 312
Query: 1965 CPASCPSPAPLTTPAVCEGPCVEGCQCDAG 1994
C +C + L ++CE ++GC C G
Sbjct: 313 CMDTC---SHLEVSSLCEEHRMDGCFCPEG 339
Score = 83.6 bits (205), Expect = 3e-15
Identities = 88/337 (26%), Positives = 127/337 (37%), Gaps = 43/337 (12%)
Query: 1248 GSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSV 1307
G + C G+ HY TFDG F F G C Y A C R FAV ++ G G+
Sbjct: 33 GHNVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDC--RGSYKEFAV---HLKRGPGQAEA 87
Query: 1308 ---TRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGL 1364
I + + + T+ L + +NG + P I S + V GL
Sbjct: 88 PAGVESILLTIKDDTIYLTRH--LAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRA--GL 143
Query: 1365 RVAYDLVYYVRVTVPGNYYQQMCGLCGNYNG-DPKDDFQKPNGSQAGNANEFGNSWEEVV 1423
+ ++ + + + + CGLCG+YNG +F + + EFGN +
Sbjct: 144 TLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFL--SDGVLFSPLEFGNMQKINQ 201
Query: 1424 PDSPCLPPTPCPPGSEDCIPS----HKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVD 1479
PD C P E+ P+ H+ E E+ E F + C LV
Sbjct: 202 PDVVCEDP------EEEVAPASCSEHRA--ECERLLTAEAF-----------ADCQDLVP 242
Query: 1480 PQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETF-----CPMECPP 1534
+ L+ C D C G + +CS + + C AGG WRT T CP
Sbjct: 243 LEPYLRACQQDRCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPG 302
Query: 1535 NSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSG 1571
N Y C CS L C++ +GC C G
Sbjct: 303 NLVYLESGSPCMDTCSHLEVSSLCEEHRMDGCFCPEG 339
Score = 79.3 bits (194), Expect = 5e-14
Identities = 75/323 (23%), Positives = 128/323 (39%), Gaps = 31/323 (9%)
Query: 864 CQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAV 923
C G+ HY +FDG F F G C Y C + F V ++ ++ + ++
Sbjct: 37 CSTWGNFHYKTFDGDVFRFPGLCDYNFASDC--RGSYKEFAVHLKRGPGQAEAPAGVESI 94
Query: 924 RVEARGVKVAVRREYPGQVLVDDVLQ---YLP---FQAADGQVQVFRQGRDAVVRTDFGL 977
+ + + + R VL V+ Y P + +D +V+ + GL
Sbjct: 95 LLTIKDDTIYLTRHLA--VLNGAVVSTPHYSPGLLIEKSDAYTKVYSRA---------GL 143
Query: 978 TVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETR 1037
T+ ++ + ++ + + CGLCG++NG + L G + L FGN Q+ +
Sbjct: 144 TLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFL-SDGVLFSPLEFGNM-QKINQ 201
Query: 1038 PGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCL 1097
P +P + + A + + EC L + F +C + + +R C DRC
Sbjct: 202 PDVVCEDPEE----EVAPASCSEHRAECERLLTAEA-FADCQDLVPLEPYLRACQQDRCR 256
Query: 1098 LPGQSGPLCDALATYAAACQAAGATVHPWRSEEL-----CPLSCPPHSHYEACSYGCPLS 1152
PG +C +A ++ C AG WR+ +CP + Y C +
Sbjct: 257 CPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDT 316
Query: 1153 CGDLPVPGGCGSECHEGCVCDEG 1175
C L V C +GC C EG
Sbjct: 317 CSHLEVSSLCEEHRMDGCFCPEG 339
Score = 36.6 bits (83), Expect = 0.38
Identities = 30/92 (32%), Positives = 47/92 (51%), Gaps = 11/92 (11%)
Query: 2894 VHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQVWLGAN 2953
V +F DG V L N L+V+LP AS SV R ++V GV++ +
Sbjct: 358 VVVFKSDGSVLL--------NELQVNLP-HVTASFSVFRPSSYHIMVSMAIGVRLQVQLA 408
Query: 2954 GKVAVIVSNDHA--GKLCGACGNFDGDQTNDW 2983
+ + V+ D A G++ G CGNF+G + +D+
Sbjct: 409 PVMQLFVTLDQASQGQVQGLCGNFNGLEGDDF 440
>gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens]
Length = 1503
Score = 208 bits (529), Expect = 7e-53
Identities = 171/519 (32%), Positives = 217/519 (41%), Gaps = 82/519 (15%)
Query: 1528 CP--MECPPNSHY----ELCADTCSLGCSALS--------APP------QCQD------- 1560
CP + CPP+ + C TC+ S S APP QCQD
Sbjct: 996 CPSLVGCPPSQLLPPGPQHCCPTCAEALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIH 1055
Query: 1561 -GCAE-GCQCDSGFLYNGQAC----VPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAG 1614
C E C G C P Q C H G + +D C C+C AG
Sbjct: 1056 QACPELSCPLSERHTPPGSCCPVCRAPTQSC--VHQGREVASGERWTVDTCTS-CSCMAG 1112
Query: 1615 KGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCW 1674
+ CQ C P LSC P P C CLP A+C
Sbjct: 1113 T-VRCQSQRCSP----------LSC---GPDKAPALSPGSCCPR------CLPR-PASCM 1151
Query: 1675 LWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRV 1734
+GDPHY +FDGR FQG+C+YVLA G F+V N +RG V++ +
Sbjct: 1152 AFGDPHYRTFDGRLLHFQGSCSYVLAKDCHSG-------DFSVHVTNDDRGRSGVAWTQE 1204
Query: 1735 VTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVS 1794
V V + + +D V V+G ALP + + + V +L A GLQV
Sbjct: 1205 VAVLLGDMAVRLLQDGA----VTVDGHPVALPF-LQEPLLYVELRGHTVILHAQPGLQVL 1259
Query: 1795 YDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPG--WD 1852
+D +V+V++P SY G CGLCGN + +D P G L PS +G SW+ W
Sbjct: 1260 WDGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWP 1319
Query: 1853 PLCWDECRGSCPTCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDVC 1912
R P + E CG L S PF+ CHA VPPE FF CV D+C
Sbjct: 1320 GRPCSAGREVDPCRAAGYRARREANARCGVLKS---SPFSRCHAVVPPEPFFAACVYDLC 1376
Query: 1913 M---GGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCP--ENSHYEVCGPPCPA 1967
G LC AL +Y + C+ AGV WR C + CP ++ CGPPCP
Sbjct: 1377 ACGPGSSADACLCDALEAYASHCRQAGVT-PTWRGPTLCVVGCPLERGFVFDECGPPCPR 1435
Query: 1968 SC-PSPAPL-TTPAVCEGPCVEGCQCDAGFVLSADRCVP 2004
+C PL A C PCV GCQC AG V C+P
Sbjct: 1436 TCFNQHIPLGELAAHCVRPCVPGCQCPAGLVEHEAHCIP 1474
Score = 207 bits (526), Expect = 2e-52
Identities = 183/560 (32%), Positives = 237/560 (42%), Gaps = 85/560 (15%)
Query: 2257 EQQESFG-GPDACGVISATDGPLAP----CHGLVPPAQYFQGCLLDACQVQGHPGGLCPA 2311
E ESF G D C V P P CH P+ GC G P CP
Sbjct: 962 EPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPS--LVGCPPSQLLPPG-PQHCCPT 1018
Query: 2312 VATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELC-GDSCP-VSCPSL---SAPEGCE 2366
A ++ C + G E PD C C LC +CP +SCP + P C
Sbjct: 1019 CAEALSNC-SEGLLGSELAPPDPC-YTCQCQDLTWLCIHQACPELSCPLSERHTPPGSCC 1076
Query: 2367 SACR---EGCVCDAGFVLSG-----DTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCE 2418
CR + CV V SG DTC C C+ G V C+ +
Sbjct: 1077 PVCRAPTQSCVHQGREVASGERWTVDTCT---SCSCM-------AGTV-----RCQSQ-R 1120
Query: 2419 CGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCL-------ANGGIHYITLDGRV 2471
C P +CGP + L G +C C RCL A G HY T DGR+
Sbjct: 1121 CSP---------LSCGPDKAPALSPG--SC----CPRCLPRPASCMAFGDPHYRTFDGRL 1165
Query: 2472 YDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGD-----LQRLLVTVAGQVVSLAQGQQ 2526
GSCSYVLA+ CH DFS+ + + G Q + V + V L Q
Sbjct: 1166 LHFQGSCSYVLAKDCH----SGDFSVHVTNDDRGRSGVAWTQEVAVLLGDMAVRLLQDGA 1221
Query: 2527 VTVDGEAVALP-VAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGL 2585
VTVDG VALP + + V G ++L GL++L+DG + + +S+P ++GR CGL
Sbjct: 1222 VTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGL 1281
Query: 2586 CGNFNGNWSDDFVLPNGSAASSVETFGAAWR-APGSSKGCGEGCGPQGCPVCLAEETAPY 2644
CGNFNG DD P G S FG +W+ + G G G + P A A
Sbjct: 1282 CGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPCRAAGYRARR 1341
Query: 2645 ESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCA---QKGDKAFLCRSLAAYTAAC 2701
E+N CG L++ PF+ C AV+ P +F CVYDLCA A LC +L AY + C
Sbjct: 1342 EANARCGVLKS--SPFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDALEAYASHC 1399
Query: 2702 QAAGVAVKPWRTDSFCPLHCPAHSHYSI------CTRTCQGSCAALSGLTG-CTTRCFEG 2754
+ AGV WR + C + CP + C RTC L L C C G
Sbjct: 1400 RQAGV-TPTWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLGELAAHCVRPCVPG 1458
Query: 2755 CECDDRFLLSQGVCIPVQDC 2774
C+C + + CIP + C
Sbjct: 1459 CQCPAGLVEHEAHCIPPEAC 1478
Score = 199 bits (507), Expect = 3e-50
Identities = 132/388 (34%), Positives = 177/388 (45%), Gaps = 43/388 (11%)
Query: 443 SCEGMQCAAG------QRCQVVG---GKAGCVAEST---------AVCRAQGDPHYTTFD 484
+C C AG QRC + KA ++ + A C A GDPHY TFD
Sbjct: 1103 TCTSCSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPASCMAFGDPHYRTFD 1162
Query: 485 GRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTR 544
GR G+CSY + + C D FSV N+ RG V++ V V +V L +
Sbjct: 1163 GRLLHFQGSCSYVLAKDCHSGD----FSVHVTNDDRGRSGVAWTQEVAVLLGDMAVRLLQ 1218
Query: 545 GEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQ 604
G V VD LP L E L V G ++ GL V +D Q+ +S+P +Q
Sbjct: 1219 D--GAVTVDGHPVALPF-LQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSYQ 1275
Query: 605 DQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDY---LCEDGCQNNCPACT 661
+ CGLCGN+NG DD P+G L P F +SW++ +G + C G + + P
Sbjct: 1276 GRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVD-PCRA 1334
Query: 662 PGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVG---GERLSLCRGL 718
G E + CG+L PF+ CH + P PF CVYDLC G LC L
Sbjct: 1335 AGYRARREANARCGVLK--SSPFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDAL 1392
Query: 719 SAYAQACLELGISVGDWRSPANCPLSCPANSR--YELCGPACPTSCNGAAAP-----SNC 771
AYA C + G++ WR P C + CP ++ CGP CP +C P ++C
Sbjct: 1393 EAYASHCRQAGVT-PTWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLGELAAHC 1451
Query: 772 SGRPCVEGCVCLPGFVASGGACVPASSC 799
RPCV GC C G V C+P +C
Sbjct: 1452 V-RPCVPGCQCPAGLVEHEAHCIPPEAC 1478
Score = 195 bits (496), Expect = 5e-49
Identities = 169/577 (29%), Positives = 236/577 (40%), Gaps = 86/577 (14%)
Query: 1858 ECRGSCPTCPEDRLEQYEGPGF-----------CGPLASGTGGPFTTCHAHVPPESFFKG 1906
+C C C + + G F C P G P CH P G
Sbjct: 946 DCCPQCSDCEHEGRKYEPGESFQPGADPCEVCICEPQPEGP--PSLRCHRRQCPS--LVG 1001
Query: 1907 CVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCP 1966
C + G + C A ++ C + G++ + C ++ + CP
Sbjct: 1002 CPPSQLLPPGPQHC-CPTCAEALSNC-SEGLLGSELAPPDPCYTCQCQDLTWLCIHQACP 1059
Query: 1967 A-SCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFW 2025
SCP T P G C C+ + R V A E W
Sbjct: 1060 ELSCPLSERHTPP----GSCCPVCRAPTQSCVHQGREV----------------ASGERW 1099
Query: 2026 ADGTCSQWCRCGPGG---GSLVCTPASCGLGEVCGLLP-SGQHGCQPVSTAECQAWGDPH 2081
TC+ C C G S C+P SCG + L P S C P A C A+GDPH
Sbjct: 1100 TVDTCTS-CSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLP-RPASCMAFGDPH 1157
Query: 2082 YVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNH 2141
Y T DG FQG+C Y+L+ CH + +F+V V N+ RG V++T+ V + + +
Sbjct: 1158 YRTFDGRLLHFQGSCSYVLAKDCH-----SGDFSVHVTNDDRGRSGVAWTQEVAVLLGDM 1212
Query: 2142 SLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRV 2201
++ L + VDG VALPF + LL+ L G V++ GL + +DG S V + V
Sbjct: 1213 AVRLLQ--DGAVTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSV 1270
Query: 2202 PAAYAASLCGLCGNYNQDPADDLKAVGG--KPA------GWQVGGAQGCGECVSKPCPS- 2252
P +Y CGLCGN+N DDL+ G P+ WQV G +PC +
Sbjct: 1271 PGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSE----GLWPGRPCSAG 1326
Query: 2253 ----PCTPEQQESFGGPDA-CGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGG 2307
PC + +A CGV+ ++ P + CH +VPP +F C+ D C PG
Sbjct: 1327 REVDPCRAAGYRARREANARCGVLKSS--PFSRCHAVVPPEPFFAACVYDLCAC--GPGS 1382
Query: 2308 -----LCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSH--YELCGDSCPVSCPSLS 2360
LC A+ Y + C+ AG WR P C + CP ++ CG CP +C +
Sbjct: 1383 SADACLCDALEAYASHCRQAGV-TPTWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQH 1441
Query: 2361 APEG-----CESACREGCVCDAGFVLSGDTCVPVGQC 2392
P G C C GC C AG V C+P C
Sbjct: 1442 IPLGELAAHCVRPCVPGCQCPAGLVEHEAHCIPPEAC 1478
Score = 195 bits (495), Expect = 6e-49
Identities = 156/463 (33%), Positives = 205/463 (44%), Gaps = 58/463 (12%)
Query: 1142 YEAC-SYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPP 1200
++AC CPLS P PG C C P SC VHQG
Sbjct: 1055 HQACPELSCPLSERHTP-PGSCCPVCRA----------------PTQSC--VHQGREVAS 1095
Query: 1201 GQTFYPGPGCDSLCHCQEGGLVSCESS-----SCGPHEACQPSGGSL--GCVAVGSSTCQ 1253
G+ + C S C C G V C+S SCGP +A S GS C+ +S C
Sbjct: 1096 GERWTVDT-CTS-CSCM-AGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPAS-CM 1151
Query: 1254 ASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITV 1313
A GDPHY TFDGR F G+C YVLA+ C + F+V N G V+ T+ + V
Sbjct: 1152 AFGDPHYRTFDGRLLHFQGSCSYVLAKDCHSGD----FSVHVTNDDRGRSGVAWTQEVAV 1207
Query: 1314 QVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYY 1373
+ + +RL Q VTV+G + LP L + G V++ GL+V +D
Sbjct: 1208 LLGDMAVRLLQ-DGAVTVDGHPVALPF-LQEPLLYVELRGHTVILHAQPGLQVLWDGQSQ 1265
Query: 1374 VRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTP 1433
V V+VPG+Y + CGLCGN+NG +DD Q P G + FGNSW+ P P
Sbjct: 1266 VEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQ---VSEGLWPGRP 1322
Query: 1434 CPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCL 1493
C G E P ++ CG+L S P S CH +V P+ C++DLC
Sbjct: 1323 CSAGRE-VDPCRAAGYRARREANAR--CGVLKS--SPFSRCHAVVPPEPFFAACVYDLCA 1377
Query: 1494 GGGNLS---ILCSNIHAYVSACQAAGGHVEP-WRTETFCPMECPPNSH--YELCADTCSL 1547
G S LC + AY S C+ AG V P WR T C + CP ++ C C
Sbjct: 1378 CGPGSSADACLCDALEAYASHCRQAG--VTPTWRGPTLCVVGCPLERGFVFDECGPPCPR 1435
Query: 1548 GCSALSAP-----PQCQDGCAEGCQCDSGFLYNGQACVPIQQC 1585
C P C C GCQC +G + + C+P + C
Sbjct: 1436 TCFNQHIPLGELAAHCVRPCVPGCQCPAGLVEHEAHCIPPEAC 1478
Score = 192 bits (488), Expect = 4e-48
Identities = 144/423 (34%), Positives = 195/423 (46%), Gaps = 41/423 (9%)
Query: 791 GACVP---ASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQ----SCPA 843
G+C P A + C QG ++A G+ W + C C+C T V C+ ++ SC
Sbjct: 1073 GSCCPVCRAPTQSCVHQGREVASGER-WTVDTCTS-CSCMAGT--VRCQSQRCSPLSCGP 1128
Query: 844 GERCSVQNGLLGCYP---DRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL 900
+ ++ G C P R +C GDPHY +FDGR F G+C+Y+L C
Sbjct: 1129 DKAPALSPG--SCCPRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKDCHSGD-- 1184
Query: 901 PAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQV 960
F V V N+ RG V++T+ V V + AVR G V VD LPF + +
Sbjct: 1185 --FSVHVTNDDRGRSGVAWTQEVAVLLGDM--AVRLLQDGAVTVDGHPVALPF-LQEPLL 1239
Query: 961 QVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGG 1020
V +G ++ GL V +D ++V VP SY CGLCGNFNG DDL G
Sbjct: 1240 YVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGL 1299
Query: 1021 QAANALAFGNSWQ--EETRPG--CGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFR 1076
+ AFGNSWQ E PG C A D + A++ ++ CG+L PF
Sbjct: 1300 LLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPCRAAGYRARR-EANARCGVL--KSSPFS 1356
Query: 1077 ECHSKLDPQGAVRDCVYDRCLL-PGQSGP--LCDALATYAAACQAAGATVHPWRSEELCP 1133
CH+ + P+ CVYD C PG S LCDAL YA+ C+ AG T WR LC
Sbjct: 1357 RCHAVVPPEPFFAACVYDLCACGPGSSADACLCDALEAYASHCRQAGVT-PTWRGPTLCV 1415
Query: 1134 LSCPPHSH--YEACSYGCPLSCGDLPVPGG-----CGSECHEGCVCDEGFALSGESCLPL 1186
+ CP ++ C CP +C + +P G C C GC C G C+P
Sbjct: 1416 VGCPLERGFVFDECGPPCPRTCFNQHIPLGELAAHCVRPCVPGCQCPAGLVEHEAHCIPP 1475
Query: 1187 ASC 1189
+C
Sbjct: 1476 EAC 1478
Score = 51.2 bits (121), Expect = 2e-05
Identities = 68/227 (29%), Positives = 81/227 (35%), Gaps = 40/227 (17%)
Query: 1071 PKGPFRECHSKL-DPQGAVRDCVYDRC----LLPGQSGPLCDALATYAAACQAAGATVHP 1125
P P R C + Q R CV C LLPG+ P C A A C GA H
Sbjct: 558 PSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECCPQCPA----PAGCPRPGAA-HA 612
Query: 1126 WRSEELCPLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLP 1185
E P P C G +SC LP P + +G C
Sbjct: 613 RHQEYFSPPGDPCRRCL--CLDGS-VSCQRLPCPPAPCAHPRQGPCCP------------ 657
Query: 1186 LASC-GCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSL-- 1242
SC GC++QG G+ F LC C EG VSCE +C P P+ G
Sbjct: 658 --SCDGCLYQGKEFASGERFPSPTAACHLCLCWEGS-VSCEPKACAPALCPFPARGDCCP 714
Query: 1243 ---GCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRP 1286
GC +G S P D R + TC+ TCG RP
Sbjct: 715 DCDGCEYLGESYLSNQEFP-----DPREPCNLCTCLGGFV-TCGRRP 755
Score = 50.8 bits (120), Expect = 2e-05
Identities = 57/229 (24%), Positives = 85/229 (37%), Gaps = 21/229 (9%)
Query: 2766 GVCIPVQDC---GCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVK 2822
G C PV C H GR + C+ CSC + + + CQ+ C P K
Sbjct: 1073 GSCCPVCRAPTQSCVHQGREVASGERWTVDTCTS-CSCMAGT-VRCQSQRCSPLSCGPDK 1130
Query: 2823 AEARN-------CWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWY 2875
A A + C C+ + TFDG Y L+ C ++
Sbjct: 1131 APALSPGSCCPRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKDCHSGDFSVH-- 1188
Query: 2876 RVVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLP--AEKLASVSVSRT 2933
V +V + D V L + V V+G V LP E L V +
Sbjct: 1189 --VTNDDRGRSGVAWTQEVAVLLGDMAVRLLQDGAVTVDGHPVALPFLQEPLLYVELR-- 1244
Query: 2934 PDGSLLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTND 2982
++++ + G+QV +V V V + G+ CG CGNF+G +D
Sbjct: 1245 -GHTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDD 1292
Score = 47.4 bits (111), Expect = 2e-04
Identities = 49/191 (25%), Positives = 66/191 (34%), Gaps = 56/191 (29%)
Query: 1098 LPGQSGPLCDALATYAAACQAAGATVHPWRSEE--------LCPLSCPPHSHYEACS-YG 1148
+PGQ P+CD C+ G H ++S+E LC + C + +C
Sbjct: 299 IPGQCCPVCDG-------CEYQG---HQYQSQETFRLQERGLC-VRCSCQAGEVSCEEQE 347
Query: 1149 CPLSCGDLPVPG-----GC---GSECHEG------------CVCDEGFALSGESCLPLAS 1188
CP++ LP G C G E EG CVC +G G P A
Sbjct: 348 CPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAP 407
Query: 1189 C---------------GCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHE 1233
C C + + GQ F CHCQ+ G V+C C P
Sbjct: 408 CQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADSPCHACHCQD-GTVTCSLVDCPPTT 466
Query: 1234 ACQPSGGSLGC 1244
+P G C
Sbjct: 467 CARPQSGPGQC 477
Score = 46.6 bits (109), Expect = 4e-04
Identities = 67/243 (27%), Positives = 82/243 (33%), Gaps = 46/243 (18%)
Query: 2240 QGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDAC 2299
+G C KPCP P GP C V CH + + Q D
Sbjct: 806 EGSMRCQKKPCPPALCPHPSP---GPCFCPV----------CHSCLSQGREHQ----DGE 848
Query: 2300 QVQGHPGGLCP-------AVATYVAACQAAGAQLGEWRRPDFCPL--QCPAHSHYELCGD 2350
+ +G P G C V+ C +L R CP C AH G
Sbjct: 849 EFEG-PAGSCEWCRCQAGQVSCVRLQCPPLPCKLQVTERGSCCPRCRGCLAHGEEHPEGS 907
Query: 2351 SC---PVSCPSLSAPEGCESACREGCVCDAGFVLSGD-TCVPVGQCG-CLHDGRYYPLGE 2405
+C S EG + R C+ G C P QC C H+GR Y GE
Sbjct: 908 RWVPPDSACSSCVCHEGVVTCARIQCISSCAQPRQGPHDCCP--QCSDCEHEGRKYEPGE 965
Query: 2406 VFYPGPE-CE-RRCECGPGGHVT-------CQEGAACGPHEECRLEDGVQACHATGCGRC 2456
F PG + CE CE P G + C C P + L G Q C T C
Sbjct: 966 SFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQ--LLPPGPQHCCPT-CAEA 1022
Query: 2457 LAN 2459
L+N
Sbjct: 1023 LSN 1025
Score = 45.8 bits (107), Expect = 6e-04
Identities = 66/252 (26%), Positives = 89/252 (35%), Gaps = 48/252 (19%)
Query: 1427 PCLPPTPCP-PGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLK 1485
PC PP PC P C PS C L YQ +EF P+ P ++CH
Sbjct: 641 PC-PPAPCAHPRQGPCCPS--CDGCL---YQGKEFASGERFPS-PTAACHLC-------- 685
Query: 1486 DCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECP----------PN 1535
LC G S+ C AC A + P+ C +C N
Sbjct: 686 -----LCWEG---SVSCEP-----KACAPA---LCPFPARGDCCPDCDGCEYLGESYLSN 729
Query: 1536 SHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYE 1595
+ + C+L C+ L C E C + +G C Q GC ++GV
Sbjct: 730 QEFPDPREPCNL-CTCLGGFVTCGRRPCEPPGCSHPLIPSGHCCPTCQ--GCRYHGVTTA 786
Query: 1596 PEQTVL--IDNCRQQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQ 1653
+T+ +D CTC G M CQ+ C P PS G C C Q
Sbjct: 787 SGETLPDPLDPTCSLCTCQEGS-MRCQKKPCPPALCPHPSPGPCFCPVCHSCLSQGREHQ 845
Query: 1654 ETCKEQGGQGVC 1665
+ + +G G C
Sbjct: 846 DGEEFEGPAGSC 857
Score = 42.7 bits (99), Expect = 0.005
Identities = 60/218 (27%), Positives = 75/218 (34%), Gaps = 45/218 (20%)
Query: 1094 DRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELC------PLSCPPHSHYEACSY 1147
D CL G+ + + AAC W C P CP + + C
Sbjct: 660 DGCLYQGKEFASGERFPSPTAACHLCLC----WEGSVSCEPKACAPALCPFPARGDCCPD 715
Query: 1148 --GCP------LSCGDLPVP----------GG---CGSECHEGCVCDEGFALSGESCLPL 1186
GC LS + P P GG CG E C SG C
Sbjct: 716 CDGCEYLGESYLSNQEFPDPREPCNLCTCLGGFVTCGRRPCEPPGCSHPLIPSGHCC--- 772
Query: 1187 ASC-GCVHQGTYHPPGQTFYP--GPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLG 1243
+C GC + G G+T P C SLC CQEG + C+ C P PS G
Sbjct: 773 PTCQGCRYHGVTTASGETLPDPLDPTC-SLCTCQEGSM-RCQKKPCPPALCPHPSPGPCF 830
Query: 1244 CVAVGSSTCQASGDPHYTTFDGRRFDF-MGTCVYVLAQ 1280
C S C + G H DG F+ G+C + Q
Sbjct: 831 CPVCHS--CLSQGREHQ---DGEEFEGPAGSCEWCRCQ 863
Score = 42.0 bits (97), Expect = 0.009
Identities = 69/258 (26%), Positives = 88/258 (34%), Gaps = 54/258 (20%)
Query: 1814 CGLCGNMDRNPNNDQVFPNGTLAPSIPI-WGGSWR------APGWDPL-----CWDECRG 1861
C C + + + FP+ T A + + W GS AP P C +C G
Sbjct: 659 CDGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAPALCPFPARGDCCPDCDG 718
Query: 1862 SCPTCPEDRLEQYEGPGFCGP--LASGTGGPFTTCHAHV--PPESFFKGCVLDVCMGGGD 1917
C E L E P P L + GG F TC PP GC + + G
Sbjct: 719 -CEYLGESYLSNQEFPDPREPCNLCTCLGG-FVTCGRRPCEPP-----GCSHPL-IPSGH 770
Query: 1918 RDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTT 1977
C+ Y A+G + D TC E S P PA CP P+P
Sbjct: 771 CCPTCQG-CRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPCPPALCPHPSP--- 826
Query: 1978 PAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCG 2037
GPC C ++ C + G H+ G EF +WCRC
Sbjct: 827 -----GPCF---------------CPVCHS---CLSQGREHQDGEEFEGPAGSCEWCRCQ 863
Query: 2038 PGGGSLV---CTPASCGL 2052
G S V C P C L
Sbjct: 864 AGQVSCVRLQCPPLPCKL 881
Score = 41.2 bits (95), Expect = 0.016
Identities = 38/124 (30%), Positives = 46/124 (37%), Gaps = 31/124 (25%)
Query: 1951 TCPENSHYEVCGPP---CPASCPSPAP-------LTTPAVCEGPCVEGCQCDAGFVLSAD 2000
+C E + E C PP CP C TTP PC C+C G +
Sbjct: 172 SCSELNCLESCTPPGECCPICCTEGGSHWEHGQEWTTPG---DPC-RICRCLEGHIQCRQ 227
Query: 2001 R-CV--------PLNNGC-----GCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCT 2046
R C PL C GC+ NG H +G + CS CRC GS+ C
Sbjct: 228 RECASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSGDPCSH-CRC--ANGSVQCE 284
Query: 2047 PASC 2050
P C
Sbjct: 285 PLPC 288
Score = 40.0 bits (92), Expect = 0.035
Identities = 65/256 (25%), Positives = 77/256 (30%), Gaps = 71/256 (27%)
Query: 1040 CGATEPGDC-PKLDSL--VAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRC 1096
C GDC P D + + S E DP+ P C G C C
Sbjct: 704 CPFPARGDCCPDCDGCEYLGESYLSNQE---FPDPREPCNLCTCL----GGFVTCGRRPC 756
Query: 1097 LLPGQSGPLCDA--LATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYG------ 1148
PG S PL + C+ G T S E P P C G
Sbjct: 757 EPPGCSHPLIPSGHCCPTCQGCRYHGVTT---ASGETLPDPLDPTCSLCTCQEGSMRCQK 813
Query: 1149 --CPLSCGDLPVPGGCGSE-CH----------------------EGCVCDEG-FALSGES 1182
CP + P PG C CH E C C G +
Sbjct: 814 KPCPPALCPHPSPGPCFCPVCHSCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQ 873
Query: 1183 CLPL---------ASC-----GCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSS 1228
C PL SC GC+ G HP G + P S C C E G+V+C
Sbjct: 874 CPPLPCKLQVTERGSCCPRCRGCLAHGEEHPEGSRWVPPDSACSSCVCHE-GVVTCARIQ 932
Query: 1229 C---------GPHEAC 1235
C GPH+ C
Sbjct: 933 CISSCAQPRQGPHDCC 948
Score = 38.1 bits (87), Expect = 0.13
Identities = 30/97 (30%), Positives = 39/97 (40%), Gaps = 15/97 (15%)
Query: 1156 LPVPGGCGS-ECHEGCV-CDEGFALSG--------ESCLPLASCGCVHQGTYHPPGQTFY 1205
+P C S CHEG V C +S C P S C H+G + PG++F
Sbjct: 910 VPPDSACSSCVCHEGVVTCARIQCISSCAQPRQGPHDCCPQCS-DCEHEGRKYEPGESFQ 968
Query: 1206 PGPGCDSLCHCQ---EG-GLVSCESSSCGPHEACQPS 1238
PG +C C+ EG + C C C PS
Sbjct: 969 PGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPS 1005
Score = 37.7 bits (86), Expect = 0.17
Identities = 65/243 (26%), Positives = 82/243 (33%), Gaps = 62/243 (25%)
Query: 2241 GCGECVSKPCPSPCTPEQQ-----ESFGGP-DACGVISATDG---------PLAPCHGLV 2285
G G+C + CP C E++ ESF P D C +G P APC +
Sbjct: 473 GPGQCCPR-CPD-CILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPL 530
Query: 2286 PPAQYFQGCLLDACQVQGHPGGLC---PAVATYVAACQAAGAQLGEWRRPDFCPLQCPAH 2342
P C A + +P G P+ + C + Q R PL CP
Sbjct: 531 PGTCCPNDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARR---CVPLPCP-- 585
Query: 2343 SHYELCGDSCPVSCPSLSAPEGCE-----------------SACREGCVCDAGFVLSGDT 2385
L G+ CP CP AP GC CR C+C G V
Sbjct: 586 EPVLLPGECCP-QCP---APAGCPRPGAAHARHQEYFSPPGDPCRR-CLCLDGSVSCQRL 640
Query: 2386 CVPVGQC-------------GCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAA 2432
P C GCL+ G+ + GE F C C G V+C E A
Sbjct: 641 PCPPAPCAHPRQGPCCPSCDGCLYQGKEFASGERFPSPTAACHLCLCWEGS-VSC-EPKA 698
Query: 2433 CGP 2435
C P
Sbjct: 699 CAP 701
Score = 37.0 bits (84), Expect = 0.29
Identities = 55/194 (28%), Positives = 70/194 (36%), Gaps = 38/194 (19%)
Query: 1071 PKGPFREC-----HSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHP 1125
P P R C H + + C Y LPG P+CD C G
Sbjct: 209 PGDPCRICRCLEGHIQCRQRECASLCPYPARPLPGTCCPVCDG-------CFLNG---RE 258
Query: 1126 WRSEELCPL-SCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCL 1184
RS E P+ S P SH C+ G + C LP P C + G+ C
Sbjct: 259 HRSGE--PVGSGDPCSHCR-CANGS-VQCEPLPCPP---------VPCRHPGKIPGQCC- 304
Query: 1185 PLASCGCVHQGTYHPPGQTF-YPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLG 1243
P+ GC +QG + +TF G C CQ G VSCE C P+ G
Sbjct: 305 PVCD-GCEYQGHQYQSQETFRLQERGLCVRCSCQAGE-VSCEEQECPVTPCALPASGRQL 362
Query: 1244 CVAVGSSTCQASGD 1257
C A C+ G+
Sbjct: 363 CPA-----CELDGE 371
Score = 36.2 bits (82), Expect = 0.50
Identities = 34/108 (31%), Positives = 42/108 (38%), Gaps = 16/108 (14%)
Query: 2362 PEGCE---SACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCE 2418
PEG AC CVC G G GC +G+ Y GE F P+ C
Sbjct: 104 PEGARWEPDACT-ACVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNGETF--SPDACTTCR 160
Query: 2419 CGPGGHVTCQEGAACGPHEECRLEDGVQACHATG--CGRCLANGGIHY 2464
C G V CQ GP C + +++C G C C GG H+
Sbjct: 161 CLTGA-VQCQ-----GP--SCSELNCLESCTPPGECCPICCTEGGSHW 200
Score = 35.8 bits (81), Expect = 0.66
Identities = 118/496 (23%), Positives = 154/496 (31%), Gaps = 95/496 (19%)
Query: 1989 CQCDAGFVLSADRCVP---LNNGCGCWANGTYHEAGSEFWADGTCSQWCRC--------G 2037
C C G A C P L + GC NG + G F D + CRC G
Sbjct: 117 CVCQDG----AAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTT--CRCLTGAVQCQG 170
Query: 2038 PGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVT--LDGHRFDFQGT 2095
P L C + GE C + + + G E GDP + L+GH Q
Sbjct: 171 PSCSELNCLESCTPPGECCPICCT-EGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRE 229
Query: 2096 CEYLLSAPCHGPP---LGAENFTVTVANEHRGSQAV------SYTRSVTLQIYNHSLT-- 2144
C L P P + EHR + V S+ R + L
Sbjct: 230 CASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPCP 289
Query: 2145 -LSARWPRKLQ------VDGV-FVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSF 2196
+ R P K+ DG + +Q G V + +G + +
Sbjct: 290 PVPCRHPGKIPGQCCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQECP 349
Query: 2197 VRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCTP 2256
V P A AS LC D + + V +P G + C CV +
Sbjct: 350 V---TPCALPASGRQLCPACELDGEEFAEGVQWEPDG------RPCTACVCQD------- 393
Query: 2257 EQQESFGGPDACGVISATDGPLAPC-HGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATY 2315
G CG + P APC H PP C D+C
Sbjct: 394 -------GVPKCGAVLC---PPAPCQHPTQPPGACCPSC--DSCTYHSQVYANGQNFTDA 441
Query: 2316 VAACQAAGAQLGE------------WRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAP- 2362
+ C A Q G RP P QC + + V S S P
Sbjct: 442 DSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPRCPDCILEEEVFVDGESFSHPR 501
Query: 2363 EGC-ESACREGCV---------CDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVF-YPGP 2411
+ C E C+EG L G TC P GC G+ YP G F +P
Sbjct: 502 DPCQECRCQEGHAHCQPRPCPRAPCAHPLPG-TCCPNDCSGCAFGGKEYPSGADFPHPSD 560
Query: 2412 ECERRCECGPGGHVTC 2427
C R C C G+V C
Sbjct: 561 PC-RLCRC-LSGNVQC 574
Score = 35.4 bits (80), Expect = 0.86
Identities = 63/240 (26%), Positives = 79/240 (32%), Gaps = 55/240 (22%)
Query: 1027 AFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQG 1086
A G W+ + RP PK CG + P P C P G
Sbjct: 374 AEGVQWEPDGRPCTACVCQDGVPK--------------CGAVLCPPAP---CQHPTQPPG 416
Query: 1087 AV----RDCVY-DRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCP-PHS 1140
A C Y + GQ+ D+ +A CQ T + P +C P S
Sbjct: 417 ACCPSCDSCTYHSQVYANGQNFTDADS-PCHACHCQDGTVTCS---LVDCPPTTCARPQS 472
Query: 1141 HYEACSYGCPLSC---GDLPVPGGCGSE----CHEGCVCDEGFA---------------L 1178
C CP C ++ V G S C E C C EG A L
Sbjct: 473 GPGQCCPRCP-DCILEEEVFVDGESFSHPRDPCQE-CRCQEGHAHCQPRPCPRAPCAHPL 530
Query: 1179 SGESCLPLASCGCVHQGTYHPPGQTF-YPGPGCDSLCHCQEGGLVSCESSSCGPHEACQP 1237
G +C P GC G +P G F +P C LC C G V C + C P +P
Sbjct: 531 PG-TCCPNDCSGCAFGGKEYPSGADFPHPSDPC-RLCRCLSGN-VQCLARRCVPLPCPEP 587
Score = 34.7 bits (78), Expect = 1.5
Identities = 39/152 (25%), Positives = 52/152 (34%), Gaps = 35/152 (23%)
Query: 714 LCRGLSAYAQACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSCN----GAAAPS 769
LCR LS Q + + P P+ P C P CP GAA
Sbjct: 564 LCRCLSGNVQCLARRCVPL-----PCPEPVLLPGE-----CCPQCPAPAGCPRPGAAHAR 613
Query: 770 NCS-----GRPCVEGCVCLPGFVASGGACVPASSC-------------GCTFQGLQLAPG 811
+ G PC C+CL G V+ P + C GC +QG + A G
Sbjct: 614 HQEYFSPPGDPC-RRCLCLDGSVSCQRLPCPPAPCAHPRQGPCCPSCDGCLYQGKEFASG 672
Query: 812 QEVWADELCQRRCTCNGATHQVTCRDKQSCPA 843
+ + C C + V+C K PA
Sbjct: 673 ERFPSPTAACHLCLCWEGS--VSCEPKACAPA 702
Score = 33.9 bits (76), Expect = 2.5
Identities = 49/184 (26%), Positives = 67/184 (36%), Gaps = 42/184 (22%)
Query: 735 WRSPANC-PLSC-PANSRYELCGPACPTSCNGAA--APSNCSGR-------PCVEGCVCL 783
W +C P +C PA + G CP C+G S S + PC C CL
Sbjct: 688 WEGSVSCEPKACAPALCPFPARGDCCP-DCDGCEYLGESYLSNQEFPDPREPC-NLCTCL 745
Query: 784 PGFVASG----------------GACVPASSCGCTFQGLQLAPGQEV--WADELCQRRCT 825
GFV G G C P GC + G+ A G+ + D C CT
Sbjct: 746 GGFVTCGRRPCEPPGCSHPLIPSGHCCPTCQ-GCRYHGVTTASGETLPDPLDPTCS-LCT 803
Query: 826 CNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDF-MG 884
C + + C+ K+ CP G C+ +C G H DG F+ G
Sbjct: 804 CQEGS--MRCQ-KKPCPPALCPHPSPG--PCFCPVCHSCLSQGREHQ---DGEEFEGPAG 855
Query: 885 TCTY 888
+C +
Sbjct: 856 SCEW 859
Score = 33.5 bits (75), Expect = 3.3
Identities = 23/87 (26%), Positives = 32/87 (36%), Gaps = 11/87 (12%)
Query: 1966 PASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCG--CWANGTYHEAGSE 2023
P +C + LT C+GP C + C P C C G++ E G E
Sbjct: 153 PDACTTCRCLTGAVQCQGPSCSELNC-------LESCTPPGECCPICCTEGGSHWEHGQE 205
Query: 2024 FWADGTCSQWCRCGPGGGSLVCTPASC 2050
+ G + CRC G + C C
Sbjct: 206 WTTPGDPCRICRCLE--GHIQCRQREC 230
>gi|37693519 BMP-binding endothelial regulator precursor protein [Homo
sapiens]
Length = 685
Score = 185 bits (469), Expect = 7e-46
Identities = 132/448 (29%), Positives = 191/448 (42%), Gaps = 43/448 (9%)
Query: 1968 SCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRC---VPLNNGCGCWANGTYHEAGSEF 2024
+C + + VC+ C CD G + C VP + C + G E
Sbjct: 255 NCTACTCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVPPEDIKVCKFGNKIFQDG-EM 313
Query: 2025 WADGTCSQWCRCGPGGGSL---VCTP-ASCGLGEVCGLLPSGQHGCQPVSTAE---CQAW 2077
W+ C+ C C G C P +SC G++ + GC P+ T + C +
Sbjct: 314 WSSINCTI-CACVKGRTECRNKQCIPISSCPQGKILN-----RKGCCPICTEKPGVCTVF 367
Query: 2078 GDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQ 2137
GDPHY T DG F+FQGTC+Y+L+ C P A F V V N+ R +++ S+T+SV L
Sbjct: 368 GDPHYNTFDGRTFNFQGTCQYVLTKDCSSP---ASPFQVLVKNDARRTRSFSWTKSVELV 424
Query: 2138 IYNHSLTL----SARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDG 2193
+ ++L + RW +G +ALP + H L G + VTT +GL +++DG
Sbjct: 425 LGESRVSLQQHLTVRW------NGSRIALPCRAPHF-HIDLDGYLLKVTTKAGLEISWDG 477
Query: 2194 DSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGK--------PAGWQVGGAQGCGEC 2245
DSFV + LCGLCGNYN DDL G W+V + C
Sbjct: 478 DSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCNRP 537
Query: 2246 VSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHP 2305
KP P C + C + + + CH V A +++ C+ D C+ H
Sbjct: 538 QRKPVPELCQGTVKVKLRAHRECQKLKSWE--FQTCHSTVDYATFYRSCVTDMCECPVHK 595
Query: 2306 GGLCPAVATYVAACQAAGAQLGEWRRPDFCPL-QCPAHSHYELCGDSCPVSCPSLSAPEG 2364
C + Y ACQ G ++ W C QC + Y+ CG C +C + +
Sbjct: 596 NCYCESFLAYTRACQREGIKV-HWEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGP 654
Query: 2365 CESACREGCVCDAGFVLSGDTCVPVGQC 2392
C C GC C A VL C+ C
Sbjct: 655 CNKPCVAGCHCPANLVLHKGRCIKPVLC 682
Score = 172 bits (436), Expect = 4e-42
Identities = 141/497 (28%), Positives = 208/497 (41%), Gaps = 65/497 (13%)
Query: 741 CP-LSCPANSRYELCGPACPT-------------SC--------NGAA-APSNCSGRPCV 777
CP LSCP + + G CP SC NG++ NC+ C
Sbjct: 203 CPILSCPQHLSHIPPGQCCPKCLGQRKVFDLPFGSCLFRSDVYDNGSSFLYDNCTACTCR 262
Query: 778 EGCVCLPGFVASGGACVPASSCGCTFQGLQLAPGQ---------------EVWADELCQR 822
+ V + G C GC + L P + E+W+ C
Sbjct: 263 DSTVVCKRKCSHPGGCDQGQE-GCCEECLLRVPPEDIKVCKFGNKIFQDGEMWSSINCTI 321
Query: 823 RCTCNGATHQVTCRDKQ-----SCPAGERCSVQNGLLGCYP---DRFGTCQGSGDPHYVS 874
G T CR+KQ SCP G+ + + GC P ++ G C GDPHY +
Sbjct: 322 CACVKGRTE---CRNKQCIPISSCPQGKILNRK----GCCPICTEKPGVCTVFGDPHYNT 374
Query: 875 FDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAV 934
FDGR F+F GTC Y+L C A+ F+VLV+N+ R +++ S+T++V + +V++
Sbjct: 375 FDGRTFNFQGTCQYVLTKDCSSPAS--PFQVLVKNDARRTRSFSWTKSVELVLGESRVSL 432
Query: 935 RREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSS 994
++ V + LP +A + + G V T GL +++D ++ V
Sbjct: 433 QQHLT--VRWNGSRIALPCRAPHFHIDL--DGYLLKVTTKAGLEISWDGDSFVEVMAAPH 488
Query: 995 YAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPKL-DS 1053
LCGLCGN+NG DDL G + F SW+ E+ C + P+L
Sbjct: 489 LKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCNRPQRKPVPELCQG 548
Query: 1054 LVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYA 1113
V +L++ EC L + F+ CHS +D R CV D C P C++ Y
Sbjct: 549 TVKVKLRAHRECQKLKSWE--FQTCHSTVDYATFYRSCVTDMCECPVHKNCYCESFLAYT 606
Query: 1114 AACQAAGATVHPWRSEELCPLS-CPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVC 1172
ACQ G VH W ++ C + C + Y+ C GC +C + G C C GC C
Sbjct: 607 RACQREGIKVH-WEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGPCNKPCVAGCHC 665
Query: 1173 DEGFALSGESCLPLASC 1189
L C+ C
Sbjct: 666 PANLVLHKGRCIKPVLC 682
Score = 165 bits (418), Expect = 5e-40
Identities = 108/363 (29%), Positives = 155/363 (42%), Gaps = 18/363 (4%)
Query: 444 CEGMQCAAGQRC---QVVGGKAGC--VAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTM 498
C QC C +++ K C E VC GDPHY TFDGR ++ GTC Y +
Sbjct: 331 CRNKQCIPISSCPQGKILNRKGCCPICTEKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVL 390
Query: 499 VELCSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSR 558
+ CS + F V KN+ R +R S+ V + VSL + + V SR
Sbjct: 391 TKDCSSPAS--PFQVLVKNDARRTRSFSWTKSVELVLGESRVSLQQ----HLTVRWNGSR 444
Query: 559 LPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDP 618
+ + + G V GL +++D D + + + ++CGLCGNYNG
Sbjct: 445 IALPCRAPHFHIDLDGYLLKVTTKAGLEISWDGDSFVEVMAAPHLKGKLCGLCGNYNGHK 504
Query: 619 ADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQ-HYEGDRLCGML 677
DD + DG D +FA SW+++ ++ C + P G + R C L
Sbjct: 505 RDDLIGGDGNFKFDVDDFAESWRVESNEF-CNRPQRKPVPELCQGTVKVKLRAHRECQKL 563
Query: 678 TKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRS 737
+ F CH T+D F CV D+C + C AY +AC GI V W
Sbjct: 564 KSWE--FQTCHSTVDYATFYRSCVTDMCECPVHKNCYCESFLAYTRACQREGIKV-HWEP 620
Query: 738 PANCPLS-CPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPA 796
NC + C + Y+ CGP C +C+ C+ +PCV GC C V G C+
Sbjct: 621 QQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGPCN-KPCVAGCHCPANLVLHKGRCIKP 679
Query: 797 SSC 799
C
Sbjct: 680 VLC 682
Score = 164 bits (415), Expect = 1e-39
Identities = 138/471 (29%), Positives = 202/471 (42%), Gaps = 62/471 (13%)
Query: 1541 CADT---CSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVP---IQQCGCYHNGVYY 1594
C D+ C CS Q Q+GC E C VP I+ C + N ++
Sbjct: 261 CRDSTVVCKRKCSHPGGCDQGQEGCCEECLLR----------VPPEDIKVCK-FGNKIFQ 309
Query: 1595 EPEQTVLIDNCRQQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQE 1654
+ E I NC C C G+ C+ C P C P G IL+ K C
Sbjct: 310 DGEMWSSI-NCTI-CACVKGR-TECRNKQCIPISSC-PQGKILN--RKGCC--------P 355
Query: 1655 TCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTP 1714
C E+ G C ++GDPHY++FDGR F+FQGTC YVL T C ++ P
Sbjct: 356 ICTEKPG----------VCTVFGDPHYNTFDGRTFNFQGTCQYVL-TKDCSSPAS----P 400
Query: 1715 FTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRI 1774
F V KN R + S+ + V + + +S+ + + V NG ALP I
Sbjct: 401 FQVLVKNDARRTRSFSWTKSVELVLGESRVSLQQH----LTVRWNGSRIALPCRAPHFHI 456
Query: 1775 SVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGT 1834
+ K A GL++S+D + V+V G +CGLCGN + + +D + +G
Sbjct: 457 DLDGYLLKVTTKA--GLEISWDGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGN 514
Query: 1835 LAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLE-QYEGPGFCGPLASGTGGPFTT 1893
+ + SWR + C R P + ++ + C L S F T
Sbjct: 515 FKFDVDDFAESWRVES-NEFCNRPQRKPVPELCQGTVKVKLRAHRECQKLKSWE---FQT 570
Query: 1894 CHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEIT-C 1952
CH+ V +F++ CV D+C ++ C++ +Y ACQ G+ + W Q C T C
Sbjct: 571 CHSTVDYATFYRSCVTDMCECPVHKNCYCESFLAYTRACQREGIKVH-WEPQQNCAATQC 629
Query: 1953 PENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCV 2003
+ Y+ CGP C +C + + C PCV GC C A VL RC+
Sbjct: 630 KHGAVYDTCGPGCIKTCDNWNEI---GPCNKPCVAGCHCPANLVLHKGRCI 677
Score = 153 bits (387), Expect = 2e-36
Identities = 124/440 (28%), Positives = 185/440 (42%), Gaps = 41/440 (9%)
Query: 2348 CGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVF 2407
C DS V S P GC+ +EGC C+ + + V C + + GE+
Sbjct: 261 CRDSTVVCKRKCSHPGGCDQG-QEGC-CEECLLRVPPEDIKV----CKFGNKIFQDGEM- 313
Query: 2408 YPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGC--------GRCLAN 2459
+ C C C G C+ C P C + + GC G C
Sbjct: 314 WSSINCTI-CACVKG-RTECRN-KQCIPISSCPQG---KILNRKGCCPICTEKPGVCTVF 367
Query: 2460 GGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVV 2519
G HY T DGR ++ G+C YVL + C VL KN A + T + ++V
Sbjct: 368 GDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQ---VLVKNDARRTRSFSWTKSVELV 424
Query: 2520 ------SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMS 2573
SL Q V +G +ALP + +G + + T GL + +DGD+ + +
Sbjct: 425 LGESRVSLQQHLTVRWNGSRIALPCRAPHFHIDLDGYLLKVTTKAGLEISWDGDSFVEVM 484
Query: 2574 IPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGC 2633
+G+LCGLCGN+NG+ DD + +G+ V+ F +WR S++ C PQ
Sbjct: 485 AAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVE-SNEFCNR---PQRK 540
Query: 2634 PV---CLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFL 2690
PV C ++ C +L++ + F TC + + + ++R CV D+C K
Sbjct: 541 PVPELCQGTVKVKLRAHRECQKLKSWE--FQTCHSTVDYATFYRSCVTDMCECPVHKNCY 598
Query: 2691 CRSLAAYTAACQAAGVAVKPWRTDSFC-PLHCPAHSHYSICTRTCQGSCAALSGLTGCTT 2749
C S AYT ACQ G+ V W C C + Y C C +C + + C
Sbjct: 599 CESFLAYTRACQREGIKVH-WEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGPCNK 657
Query: 2750 RCFEGCECDDRFLLSQGVCI 2769
C GC C +L +G CI
Sbjct: 658 PCVAGCHCPANLVLHKGRCI 677
Score = 151 bits (381), Expect = 1e-35
Identities = 135/501 (26%), Positives = 198/501 (39%), Gaps = 64/501 (12%)
Query: 1130 ELCP-LSCPPHSHYEACSYGCPLSCG-----DLPVPGGC--GSECHEG-----------C 1170
E+CP LSCP H + CP G DLP G C S+ ++ C
Sbjct: 201 EVCPILSCPQHLSHIPPGQCCPKCLGQRKVFDLPF-GSCLFRSDVYDNGSSFLYDNCTAC 259
Query: 1171 VCDEGFALSGESCLPLASC-----GCVHQGTYHPP----------GQTFYPGPGCDSL-- 1213
C + + C C GC + P + F G S+
Sbjct: 260 TCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVPPEDIKVCKFGNKIFQDGEMWSSINC 319
Query: 1214 --CHCQEGGLVSCESSSCGPHEACQPSGGSL---GCVAVGSS---TCQASGDPHYTTFDG 1265
C C +G C + C P +C P G L GC + + C GDPHY TFDG
Sbjct: 320 TICACVKGR-TECRNKQCIPISSC-PQGKILNRKGCCPICTEKPGVCTVFGDPHYNTFDG 377
Query: 1266 RRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQR 1325
R F+F GTC YVL + C + F VL +N A S T+ + + + + L+Q
Sbjct: 378 RTFNFQGTCQYVLTKDCSSPAS--PFQVLVKNDARRTRSFSWTKSVELVLGESRVSLQQH 435
Query: 1326 QWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQ 1385
V NG + LP + I G + + T GL +++D +V V + +
Sbjct: 436 L-TVRWNGSRIALPCRAPHFHIDLD--GYLLKVTTKAGLEISWDGDSFVEVMAAPHLKGK 492
Query: 1386 MCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSH 1445
+CGLCGNYNG +DD +G+ + ++F SW V + C P P +P
Sbjct: 493 LCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWR-VESNEFCNRPQRKP------VPE- 544
Query: 1446 KCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNI 1505
C ++ K + C L S +CH VD + C+ D+C + + C +
Sbjct: 545 LCQGTVKVKLRAHRECQKLKS--WEFQTCHSTVDYATFYRSCVTDMCECPVHKNCYCESF 602
Query: 1506 HAYVSACQAAGGHVEPWRTETFCPM-ECPPNSHYELCADTCSLGCSALSAPPQCQDGCAE 1564
AY ACQ G V W + C +C + Y+ C C C + C C
Sbjct: 603 LAYTRACQREGIKVH-WEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGPCNKPCVA 661
Query: 1565 GCQCDSGFLYNGQACVPIQQC 1585
GC C + + + C+ C
Sbjct: 662 GCHCPANLVLHKGRCIKPVLC 682
Score = 56.6 bits (135), Expect = 4e-07
Identities = 60/268 (22%), Positives = 96/268 (35%), Gaps = 25/268 (9%)
Query: 2721 CPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQDCGCTHNG 2780
C +C R C G GC C + +P +D G
Sbjct: 259 CTCRDSTVVCKRKCSHPGGCDQGQEGCCEECL--------------LRVPPEDIKVCKFG 304
Query: 2781 RYLPVNSSLLTSDCSERCSC----SSSSGLTC-QAAGCPPGRVCEVKAEARNCWATRGLC 2835
+ + + +S C+C + C + CP G++ K C G+C
Sbjct: 305 NKIFQDGEMWSSINCTICACVKGRTECRNKQCIPISSCPQGKILNRKGCCPICTEKPGVC 364
Query: 2836 VLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVGQVH 2895
+ + TFDG Y L+ C + P+ +V V
Sbjct: 365 TVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPAS--PFQVLVKNDARRTRSFSWTKSVE 422
Query: 2896 IFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDGSLL-VRQKAGVQVWLGANG 2954
+ + V+L + V NG R+ LP + DG LL V KAG+++ +
Sbjct: 423 LVLGESRVSLQQHLTVRWNGSRIALPCR---APHFHIDLDGYLLKVTTKAGLEISWDGDS 479
Query: 2955 KVAVIVSNDHAGKLCGACGNFDGDQTND 2982
V V+ + GKLCG CGN++G + +D
Sbjct: 480 FVEVMAAPHLKGKLCGLCGNYNGHKRDD 507
Score = 34.7 bits (78), Expect = 1.5
Identities = 35/140 (25%), Positives = 47/140 (33%), Gaps = 33/140 (23%)
Query: 757 ACPTSCNGAAAPSN--------------CSGRPCVEGCVCLPGF---------VASGGAC 793
AC C G N C R C EG V G + G C
Sbjct: 100 ACCEQCKGCTYEGNTYNSSFKWQSPAEPCVLRQCQEGVVTESGVRCVVHCKNPLEHLGMC 159
Query: 794 VPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQ--------VTCRDKQS-CPAG 844
P GC F+G+Q G+E + +C+C G Q ++C S P G
Sbjct: 160 CPTCP-GCVFEGVQYQEGEEFQPEGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPG 218
Query: 845 ERCSVQNGLLGCYPDRFGTC 864
+ C G + FG+C
Sbjct: 219 QCCPKCLGQRKVFDLPFGSC 238
>gi|239755776 PREDICTED: similar to Mucin-19 [Homo sapiens]
Length = 1950
Score = 171 bits (434), Expect = 8e-42
Identities = 155/624 (24%), Positives = 252/624 (40%), Gaps = 85/624 (13%)
Query: 1016 LRGGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSK-NECGILADPKGP 1074
+ GG + N Q+ + PGDCP + + +CG +A
Sbjct: 628 IESGGDFNIEIKRNNDRQDINEHIANSKIPGDCPNAVGKSYEVCEDGIQKCGKVAALSND 687
Query: 1075 FRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAG-ATVHPWRSEE--L 1131
++ C+ + C ++ CD + + C + G T WRS+ +
Sbjct: 688 YKMI------------CIDEYCQTRDKTST-CDTYSELSRLCASDGPGTFESWRSDSDVV 734
Query: 1132 CPLS-CPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALS--GES--CLPL 1186
C CP Y+ C P +C + V SEC GC C EG+ L GE C+
Sbjct: 735 CETQRCPEQHIYKECGPSNPATCSN--VAPFQDSECVSGCTCPEGYLLDDIGEKGKCVLK 792
Query: 1187 ASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVA 1246
A C C GT + PG+ GP C S C CQ+ SC + C C+ G SL
Sbjct: 793 AECPCESSGTVYQPGEV-REGP-CGSQCTCQDAKW-SCTEALCPGR--CKVEGSSL---- 843
Query: 1247 VGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVS 1306
TTFDG +++F G C ++ +++ E +G+
Sbjct: 844 --------------TTFDGVKYNFPGNCHFLAVHN-------EDWSISVELRPCPSGQTG 882
Query: 1307 VTRVITVQVANFTLRLEQRQWKV--TVNGVDMKLPVVLANGQIRASQHGSDVV-IETDFG 1363
+ N ++ +++ + TV ++ + +I+ S + +ET F
Sbjct: 883 TCLNSVTLLLNSSVPVDKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASSSYLQVETYFH 942
Query: 1364 LRVAYDLVYYVR--VTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEE 1421
+++ +V ++ V++P N + GLCG+YN +DDF + F NSWE
Sbjct: 943 VKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEM 1002
Query: 1422 VVPDSPCLPPTPCPPGS-EDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDP 1480
+ CP G+ CI +EK+ E CG+L +GPL+SCH +V+P
Sbjct: 1003 M----------SCPKGNPSSCI-------SIEKEKFAERHCGILLDSSGPLASCHPIVNP 1045
Query: 1481 QGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYEL 1540
+ ++C C + LC+ + YV AC ++ WRT C CP ++
Sbjct: 1046 KPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRT-GLCEHSCPSGLVFKY 1104
Query: 1541 CADTCSLGCSALSAPPQ---CQDGCAEGCQCDSGFLYNGQA-CVPIQQCGCYHNGVYYEP 1596
C+ C +LS + +D +GC C N + CV QC CY N +P
Sbjct: 1105 NVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQP 1164
Query: 1597 EQTVLIDNCRQQCTCHAGKGMVCQ 1620
+ + D+ +C C G ++CQ
Sbjct: 1165 GKLIHTDD--NKCVCRDGI-LLCQ 1185
Score = 135 bits (339), Expect = 8e-31
Identities = 143/552 (25%), Positives = 211/552 (38%), Gaps = 99/552 (17%)
Query: 1907 CVLDVCMGGGDRDILCKALASYVAACQAAGV-VIEDWRAQ--VGCEIT-CPENSHYEVCG 1962
C+ + C D+ C + C + G E WR+ V CE CPE Y+ CG
Sbjct: 692 CIDEYCQTR-DKTSTCDTYSELSRLCASDGPGTFESWRSDSDVVCETQRCPEQHIYKECG 750
Query: 1963 PPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLS----ADRCVPLNNGCGCWANGTYH 2018
P PA+C + AP + CV GC C G++L +CV L C C ++GT +
Sbjct: 751 PSNPATCSNVAPFQ-----DSECVSGCTCPEGYLLDDIGEKGKCV-LKAECPCESSGTVY 804
Query: 2019 EAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWG 2078
+ G +G C C C S CT A C C+ G
Sbjct: 805 QPGEV--REGPCGSQCTCQDAKWS--CTEALC--------------------PGRCKVEG 840
Query: 2079 DPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGS-QAVSYTRSVTL- 2136
T DG +++F G C +L + E+++++V S Q + SVTL
Sbjct: 841 SS-LTTFDGVKYNFPGNCHFLA--------VHNEDWSISVELRPCPSGQTGTCLNSVTLL 891
Query: 2137 ---------QIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGL 2187
++N T++ K++ G + + Q+ + ++L V T +
Sbjct: 892 LNSSVPVDKYVFNSDGTVTND---KIRNQGYYYSDKIQIFNASSSYLQ-----VETYFHV 943
Query: 2188 SLAFDGDSFVRLRV--PAAYAASLCGLCGNYNQDPADDL--------KAVGGKPAGWQVG 2237
L ++L V P GLCG+YN DD K W++
Sbjct: 944 KLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEM- 1002
Query: 2238 GAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLD 2297
C K PS C ++E F CG++ + GPLA CH +V P Y + C
Sbjct: 1003 --MSC----PKGNPSSCISIEKEKFAERH-CGILLDSSGPLASCHPIVNPKPYHEECKKY 1055
Query: 2298 ACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCP 2357
C + LC + YV AC + W R C CP+ ++ +C SC
Sbjct: 1056 TCTCENSQDCLCTILGNYVKACAEKETYIVGW-RTGLCEHSCPSGLVFKYNVKACNSSCR 1114
Query: 2358 SLSAPE---GCESACREGCVC-DAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGP-- 2411
SLS + E +GC C DA + + CV QC C Y EV PG
Sbjct: 1115 SLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDC------YINDEVMQPGKLI 1168
Query: 2412 -ECERRCECGPG 2422
+ +C C G
Sbjct: 1169 HTDDNKCVCRDG 1180
Score = 130 bits (327), Expect = 2e-29
Identities = 134/596 (22%), Positives = 225/596 (37%), Gaps = 74/596 (12%)
Query: 643 DDGDYLCEDGCQNNCPACTPGQAQHYE-GDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCV 701
D +++ +CP + E G + CG + L + + C+
Sbjct: 646 DINEHIANSKIPGDCPNAVGKSYEVCEDGIQKCGKVAALSNDYKMI------------CI 693
Query: 702 YDLCVVGGERLSLCRGLSAYAQACLELGISVGD-WRSPANCPLS---CPANSRYELCGPA 757
+ C ++ S C S ++ C G + WRS ++ CP Y+ CGP+
Sbjct: 694 DEYCQTR-DKTSTCDTYSELSRLCASDGPGTFESWRSDSDVVCETQRCPEQHIYKECGPS 752
Query: 758 CPTSCNGAAAPSNCSGRPCVEGCVCLPGF----VASGGACVPASSCGCTFQGLQLAPGQE 813
P +C+ A + CV GC C G+ + G CV + C C G PG+
Sbjct: 753 NPATCSNVAPFQDSE---CVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGEV 809
Query: 814 VWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYV 873
+ C +CTC A T + CP RC V+ L
Sbjct: 810 --REGPCGSQCTCQDAKWSCT---EALCPG--RCKVEGSSL------------------T 844
Query: 874 SFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVA 933
+FDG +++F G C +L V + ++ ++ + G+ S T + K
Sbjct: 845 TFDGVKYNFPGNCHFLAVHN--EDWSISVELRPCPSGQTGTCLNSVTLLLNSSVPVDKYV 902
Query: 934 VRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAV-VRTDFG--LTVTYDWNARVTAK 990
+ + +D ++ + +D ++Q+F + V T F L + ++
Sbjct: 903 FNSD---GTVTNDKIRNQGYYYSD-KIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVS 958
Query: 991 VPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPK 1050
+P + GLCG++N DD + AF NSW+ + C P C
Sbjct: 959 MPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMS---CPKGNPSSCIS 1015
Query: 1051 LDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALA 1110
++ ++ ++ CGIL D GP CH ++P+ +C C LC L
Sbjct: 1016 IE----KEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILG 1071
Query: 1111 TYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPV-PGGCGSE--CH 1167
Y AC + WR+ LC SCP ++ C SC L C E
Sbjct: 1072 NYVKACAEKETYIVGWRT-GLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPV 1130
Query: 1168 EGCVCDEGFALSGE-SCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLV 1222
+GC C + + E +C+ + C C PG+ + D+ C C++G L+
Sbjct: 1131 DGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHTD---DNKCVCRDGILL 1183
Score = 130 bits (327), Expect = 2e-29
Identities = 139/589 (23%), Positives = 205/589 (34%), Gaps = 92/589 (15%)
Query: 2250 CPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLC 2309
CP+ + G CG ++A Y C+ + CQ + C
Sbjct: 660 CPNAVGKSYEVCEDGIQKCGKVAALSN------------DYKMICIDEYCQTRDKTS-TC 706
Query: 2310 PAVATYVAACQAAGAQLGEWRRPD---FCPLQ-CPAHSHYELCGDSCPVSCPSLSAPEGC 2365
+ C + G E R D C Q CP Y+ CG S P +C +++ +
Sbjct: 707 DTYSELSRLCASDGPGTFESWRSDSDVVCETQRCPEQHIYKECGPSNPATCSNVAPFQ-- 764
Query: 2366 ESACREGCVCDAGFVLSG----DTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGP 2421
+S C GC C G++L CV +C C G Y GEV R CG
Sbjct: 765 DSECVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGEV--------REGPCG- 815
Query: 2422 GGHVTCQEGAACGPHEECRLEDGVQACHATGC-GRCLANGGIHYITLDGRVYDLHGSCSY 2480
+C +D +C C GRC G T DG Y+ G+C +
Sbjct: 816 ---------------SQCTCQDAKWSCTEALCPGRCKVEGS-SLTTFDGVKYNFPGNCHF 859
Query: 2481 VLAQVCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAV 2540
+ +ED+SI +E Q V+L V VD V
Sbjct: 860 LAVH-------NEDWSISVELRPCPSGQ---TGTCLNSVTLLLNSSVPVDKYVFNSDGTV 909
Query: 2541 GRVRVTAEG------------RNMVLQTTK----GLRLLFDGDAHLLMSIPSPFRGRLCG 2584
++ +G + LQ L++ L +S+P G
Sbjct: 910 TNDKIRNQGYYYSDKIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVG 969
Query: 2585 LCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPY 2644
LCG++N DDF+ + + F +W KG P C E+ A
Sbjct: 970 LCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMSCPKG-----NPSSCISIEKEKFA-- 1022
Query: 2645 ESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAA 2704
CG L + GP A+C +++P Y +C C + + LC L Y AC
Sbjct: 1023 --ERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEK 1080
Query: 2705 GVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGL-TGCTTR--CFEGCECDD-R 2760
+ WRT C CP+ + + C SC +LS C +GC C D
Sbjct: 1081 ETYIVGWRT-GLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAM 1139
Query: 2761 FLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQ 2809
+ ++G C+ C C N + + T D +C C L CQ
Sbjct: 1140 YQNNEGNCVLKSQCDCYINDEVMQPGKLIHTDD--NKCVCRDGI-LLCQ 1185
Score = 115 bits (289), Expect = 5e-25
Identities = 139/611 (22%), Positives = 221/611 (36%), Gaps = 98/611 (16%)
Query: 1447 CPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIH 1506
CP + K Y+ E LS+ +K++ CI + C S C
Sbjct: 660 CPNAVGKSYEVCEDGIQKCGKVAALSNDYKMI--------CIDEYCQTRDKTST-CDTYS 710
Query: 1507 AYVSACQAAG-GHVEPWRTETFCPME---CPPNSHYELCADTCSLGCSALSAPPQCQDGC 1562
C + G G E WR+++ E CP Y+ C + CS ++ P C
Sbjct: 711 ELSRLCASDGPGTFESWRSDSDVVCETQRCPEQHIYKECGPSNPATCSNVA--PFQDSEC 768
Query: 1563 AEGCQCDSGFLYNGQA----CVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMV 1618
GC C G+L + CV +C C +G Y+P + V C QCTC K
Sbjct: 769 VSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGE-VREGPCGSQCTCQDAKWS- 826
Query: 1619 CQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGD 1678
C E C PG+ CK +G
Sbjct: 827 CTEALC-PGR---------------------------CKVEGSS---------------- 842
Query: 1679 PHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVA 1738
+FDG K++F G C+++ +S + L P + + VT+
Sbjct: 843 --LTTFDGVKYNFPGNCHFLAVHNEDWSISVE-LRPCP--------SGQTGTCLNSVTLL 891
Query: 1739 ALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVADF---GLQVSY 1795
L +++ + K N + +D +I + +S L V + LQ+
Sbjct: 892 -LNSSVPVDKYVFNSDGTVTNDKIRNQGYYYSD-KIQIFNASSSYLQVETYFHVKLQIQI 949
Query: 1796 DWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLC 1855
++ V++P + GLCG+ + +D + L + + SW C
Sbjct: 950 VPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMS----C 1005
Query: 1856 WDECRGSCPTCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDVCMGG 1915
SC + +++ + CG L +G P +CH V P+ + + C C
Sbjct: 1006 PKGNPSSCISIEKEKFAERH----CGILLDSSG-PLASCHPIVNPKPYHEECKKYTCTCE 1060
Query: 1916 GDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPL 1975
+D LC L +YV AC I WR + CE +CP ++ C +SC S +
Sbjct: 1061 NSQDCLCTILGNYVKACAEKETYIVGWRTGL-CEHSCPSGLVFKYNVKACNSSCRSLSER 1119
Query: 1976 TTPAVCEGPCVEGCQC-DAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWC 2034
E V+GC C DA + + CV L + C C+ N + G D
Sbjct: 1120 DRSCDVEDVPVDGCTCPDAMYQNNEGNCV-LKSQCDCYINDEVMQPGKLIHTDDN----- 1173
Query: 2035 RCGPGGGSLVC 2045
+C G L+C
Sbjct: 1174 KCVCRDGILLC 1184
Score = 115 bits (287), Expect = 9e-25
Identities = 112/431 (25%), Positives = 170/431 (39%), Gaps = 55/431 (12%)
Query: 452 GQRCQVVGGKAGCV-AESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPA 510
G +C K C A C+ +G TTFDG +Y+ G C + V +ED ++
Sbjct: 815 GSQCTCQDAKWSCTEALCPGRCKVEGSS-LTTFDGVKYNFPGNCHFLAVH--NEDWSISV 871
Query: 511 FSVEAKNEHRGSRRVSYVGL----VTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEG 566
+ G+ S L V V Y + T V N + R
Sbjct: 872 ELRPCPSGQTGTCLNSVTLLLNSSVPVDKYVFNSDGT--------VTNDKIRNQGYYYSD 923
Query: 567 RLRVYQSGPRAV-VELVFG--LVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFL 623
+++++ + + VE F L + QL +S+P GLCG+YN DDF+
Sbjct: 924 KIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFM 983
Query: 624 TPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGP 683
+ L + FA+SW++ C G N +C + + + +R CG+L GP
Sbjct: 984 SSQNILEKTSQAFANSWEMMS----CPKG---NPSSCISIEKEKF-AERHCGILLDSSGP 1035
Query: 684 FAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPL 743
A CH ++P+P+ E+C C + LC L Y +AC E + WR+ C
Sbjct: 1036 LASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRT-GLCEH 1094
Query: 744 SCPANSRYELCGPACPTSCNGAAAPSNCSGRPC------VEGCVCLPGFVASG-GACVPA 796
SCP+ ++ AC +SC + R C V+GC C + G CV
Sbjct: 1095 SCPSGLVFKYNVKACNSSCRSLSE----RDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLK 1150
Query: 797 SSCGCTFQGLQLAPGQEVWADE----------LCQ-----RRCTCNGATHQVTCRD-KQS 840
S C C + PG+ + D+ LCQ C+G V C D K
Sbjct: 1151 SQCDCYINDEVMQPGKLIHTDDNKCVCRDGILLCQIPIDLTLQNCSGGAEYVDCSDPKAQ 1210
Query: 841 CPAGERCSVQN 851
CS +N
Sbjct: 1211 RRTNRTCSTRN 1221
Score = 110 bits (276), Expect = 2e-23
Identities = 83/252 (32%), Positives = 112/252 (44%), Gaps = 24/252 (9%)
Query: 990 KVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCP 1049
K+ ++ +CGLCGN NGD DD R A+ AL FGNSW +T C T P
Sbjct: 1255 KIIVAFQGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSW--KTSQECSDTVAQTFP 1312
Query: 1050 KLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCL--LPGQSGPLCD 1107
DS + + +C IL D FR+CH+K+DP C+ + C + G+ C
Sbjct: 1313 -CDSNPYCKAWAVRKCEILRD--STFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCT 1369
Query: 1108 ALATYAAACQAAGATVHPWRSEELCPLSCPPHS-------HYEACSYGCPLSCGDLPVPG 1160
A+A YA AC A G V WR LCP+ C ++ HYE C +C D V G
Sbjct: 1370 AVAMYAEACSAVGVCV-SWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLV-G 1427
Query: 1161 GCGSECHEGCV--CDEGFALSGES---CLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCH 1215
S EGC C + E+ C+ L+ C C + P G C C+
Sbjct: 1428 QKFSSLLEGCYAKCPDSAPYLDENTMKCVSLSECSCFYNDVI-PAGGVI--EDNCGRTCY 1484
Query: 1216 CQEGGLVSCESS 1227
C G L E++
Sbjct: 1485 CIAGQLECSETA 1496
Score = 108 bits (271), Expect = 6e-23
Identities = 76/238 (31%), Positives = 103/238 (43%), Gaps = 26/238 (10%)
Query: 603 FQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTP 662
FQ +VCGLCGN NGD DDF T ++A A+EF +SWK C D P C
Sbjct: 1260 FQGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQE---CSDTVAQTFP-CDS 1315
Query: 663 GQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCV--VGGERLSLCRGLSA 720
R C +L D F CH+ +DP + + C+ + C + G+ L C ++
Sbjct: 1316 NPYCKAWAVRKCEILR--DSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAM 1373
Query: 721 YAQACLELGISVGDWRSPANCPLSC-----PANSR--YELCGPACPTSCNGAAAPSNCSG 773
YA+AC +G+ V WR P CP+ C P R YE CG +C S
Sbjct: 1374 YAEACSAVGVCV-SWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQKFSS 1432
Query: 774 RPCVEGCVC-----LPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTC 826
+EGC P + CV S C C + + A G ++ C R C C
Sbjct: 1433 --LLEGCYAKCPDSAPYLDENTMKCVSLSECSCFYNDVIPAGGV---IEDNCGRTCYC 1485
Score = 103 bits (258), Expect = 2e-21
Identities = 86/315 (27%), Positives = 126/315 (40%), Gaps = 55/315 (17%)
Query: 2578 FRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCL 2637
F+G++CGLCGN NG+ DDF S AS FG +W+ +S+ C +
Sbjct: 1260 FQGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWK---TSQECSD----------T 1306
Query: 2638 AEETAPYESN--------EACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCA--QKGDK 2687
+T P +SN C LR+ F C + PS Y C+ + CA +G
Sbjct: 1307 VAQTFPCDSNPYCKAWAVRKCEILRD--STFRDCHNKVDPSAYHDVCIEEACACDMEGKY 1364
Query: 2688 AFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHS-------HYSIC----TRTCQG 2736
C ++A Y AC A GV V WR + CP++C ++ HY C +TC+
Sbjct: 1365 LGFCTAVAMYAEACSAVGVCVS-WRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKD 1423
Query: 2737 SCAA---LSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSD 2793
S L GC +C + D + C+ + +C C +N +P ++ +
Sbjct: 1424 QLVGQKFSSLLEGCYAKCPDSAPYLDENTMK---CVSLSECSCFYND-VIPA-GGVIEDN 1478
Query: 2794 CSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGAT 2853
C C C + L C P V T +LS GA +T G
Sbjct: 1479 CGRTCYCIAGQ-LECSET-APTNSTFAVS-------TTTATTILSTGAAITLVTGGPSTA 1529
Query: 2854 TS-PGVYELSSRCPG 2867
S P + SS G
Sbjct: 1530 ASIPAITTSSSETTG 1544
Score = 102 bits (254), Expect = 6e-21
Identities = 81/251 (32%), Positives = 105/251 (41%), Gaps = 33/251 (13%)
Query: 1385 QMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPT-PCPPGSEDCIP 1443
++CGLCGN NGD KDDF S A A EFGNSW+ S + T PC D P
Sbjct: 1263 KVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQTFPC-----DSNP 1317
Query: 1444 SHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGG--GNLSIL 1501
C +K C +L T CH VDP CI + C G
Sbjct: 1318 --YCKAWAVRK------CEILRDST--FRDCHNKVDPSAYHDVCIEEACACDMEGKYLGF 1367
Query: 1502 CSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNS-------HYELCADTCSLGCSALSA 1554
C+ + Y AC A G V WR CP+ C + HYE C + C
Sbjct: 1368 CTAVAMYAEACSAVGVCVS-WRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLV 1426
Query: 1555 PPQCQ---DGCAEGCQCDSGFL-YNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCT 1610
+ +GC C + +L N CV + +C C++N V P V+ DNC + C
Sbjct: 1427 GQKFSSLLEGCYAKCPDSAPYLDENTMKCVSLSECSCFYNDVI--PAGGVIEDNCGRTCY 1484
Query: 1611 CHAGKGMVCQE 1621
C AG+ + C E
Sbjct: 1485 CIAGQ-LECSE 1494
Score = 94.7 bits (234), Expect = 1e-18
Identities = 75/256 (29%), Positives = 106/256 (41%), Gaps = 38/256 (14%)
Query: 2200 RVPAAYAASLCGLCGNYNQDPADDLK------AVGGKPAGWQVGGAQGCGECVSKPCPSP 2253
++ A+ +CGLCGN N D DD A G G +Q C + V++ P
Sbjct: 1255 KIIVAFQGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQTFPCD 1314
Query: 2254 CTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDAC--QVQGHPGGLCPA 2311
P + C ++ D CH V P+ Y C+ +AC ++G G C A
Sbjct: 1315 SNPYCKA--WAVRKCEILR--DSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTA 1370
Query: 2312 VATYVAACQAAGAQLGEWRRPDFCPLQCPAHS-------HYELCGDSCPVSCPS------ 2358
VA Y AC A G + WR+P+ CP+ C ++ HYE CG +C
Sbjct: 1371 VAMYAEACSAVGVCV-SWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQK 1429
Query: 2359 -LSAPEGCESACREGCVCDAGFVLSGDT--CVPVGQCGCLHDGRYYPLGEVFYPGPECER 2415
S EGC + C D+ L +T CV + +C C ++ P G V C R
Sbjct: 1430 FSSLLEGCYAKCP-----DSAPYLDENTMKCVSLSECSCFYND-VIPAGGVI--EDNCGR 1481
Query: 2416 RCECGPGGHVTCQEGA 2431
C C G + C E A
Sbjct: 1482 TCYC-IAGQLECSETA 1496
Score = 67.8 bits (164), Expect = 2e-10
Identities = 63/243 (25%), Positives = 95/243 (39%), Gaps = 24/243 (9%)
Query: 1808 SYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCP 1867
++ G VCGLCGN + + +D ++A +G SW+ C D + P C
Sbjct: 1259 AFQGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKT---SQECSDTVAQTFP-CD 1314
Query: 1868 EDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDIL--CKAL 1925
+ + C L T F CH V P ++ C+ + C + L C A+
Sbjct: 1315 SNPYCKAWAVRKCEILRDST---FRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAV 1371
Query: 1926 ASYVAACQAAGVVIEDWRAQVGCEITCPENS-------HYEVCGPPCPASCPSP-APLTT 1977
A Y AC A GV + WR C + C + HYE CG +C
Sbjct: 1372 AMYAEACSAVGVCV-SWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQKF 1430
Query: 1978 PAVCEGPCVEGCQCDAGFV-LSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRC 2036
++ EG C C A ++ + +CV L+ C C+ N G + C + C C
Sbjct: 1431 SSLLEG-CYAKCPDSAPYLDENTMKCVSLSE-CSCFYNDVIPAGGV---IEDNCGRTCYC 1485
Query: 2037 GPG 2039
G
Sbjct: 1486 IAG 1488
Score = 60.1 bits (144), Expect = 3e-08
Identities = 51/197 (25%), Positives = 82/197 (41%), Gaps = 33/197 (16%)
Query: 2663 CQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAV-KPWRTDS--FCPL 2719
C V + S ++ D Q DK C + + + C + G + WR+DS C
Sbjct: 678 CGKVAALSNDYKMICIDEYCQTRDKTSTCDTYSELSRLCASDGPGTFESWRSDSDVVCET 737
Query: 2720 H-CPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLL----SQGVCIPVQDC 2774
CP Y C + +C+ ++ + C GC C + +LL +G C+ +C
Sbjct: 738 QRCPEQHIYKECGPSNPATCSNVAPFQD--SECVSGCTCPEGYLLDDIGEKGKCVLKAEC 795
Query: 2775 GCTHNGR-YLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATRG 2833
C +G Y P + C +C+C + +C A C PGR C+V+
Sbjct: 796 PCESSGTVYQP--GEVREGPCGSQCTCQDAK-WSCTEALC-PGR-CKVE----------- 839
Query: 2834 LCVLSVGANLTTFDGAR 2850
G++LTTFDG +
Sbjct: 840 ------GSSLTTFDGVK 850
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.137 0.454
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 140,355,493
Number of Sequences: 37866
Number of extensions: 7722599
Number of successful extensions: 28247
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 64
Number of HSP's successfully gapped in prelim test: 279
Number of HSP's that attempted gapping in prelim test: 19557
Number of HSP's gapped (non-prelim): 4751
length of query: 3003
length of database: 18,247,518
effective HSP length: 120
effective length of query: 2883
effective length of database: 13,703,598
effective search space: 39507473034
effective search space used: 39507473034
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 71 (32.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.