Guide to the Human Genome
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Search of human proteins with 239749989

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239749989 PREDICTED: otogelin isoform 2 [Homo sapiens]
         (2852 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239749989 PREDICTED: otogelin isoform 2 [Homo sapiens]            6019   0.0  
gi|239755545 PREDICTED: otogelin isoform 1 [Homo sapiens]            6016   0.0  
gi|239744300 PREDICTED: otogelin isoform 2 [Homo sapiens]            6016   0.0  
gi|239749987 PREDICTED: otogelin isoform 1 [Homo sapiens]            6006   0.0  
gi|239755543 PREDICTED: otogelin isoform 2 [Homo sapiens]            6003   0.0  
gi|239744298 PREDICTED: otogelin isoform 1 [Homo sapiens]            6003   0.0  
gi|239755901 PREDICTED: chromosome 12 open reading frame 64 [Hom...  1167   0.0  
gi|239750386 PREDICTED: chromosome 12 open reading frame 64 [Hom...  1167   0.0  
gi|239744688 PREDICTED: hypothetical protein LOC283310 [Homo sap...  1167   0.0  
gi|89191868 von Willebrand factor preproprotein [Homo sapiens]        654   0.0  
gi|116284392 mucin 2 precursor [Homo sapiens]                         615   e-175
gi|169202626 PREDICTED: similar to mucin 5, partial [Homo sapiens]    612   e-174
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]      574   e-163
gi|161019170 mucin 5AC [Homo sapiens]                                 570   e-162
gi|134031945 SCO-spondin [Homo sapiens]                               546   e-155
gi|151301154 mucin 6, gastric [Homo sapiens]                          512   e-144
gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo ...   476   e-133
gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo ...   476   e-133
gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]             430   e-119
gi|239751787 PREDICTED: hypothetical protein XP_002348012 [Homo ...   310   2e-83
gi|154146262 Fc fragment of IgG binding protein [Homo sapiens]        308   4e-83
gi|239757282 PREDICTED: similar to Fc fragment of IgG binding pr...   297   9e-80
gi|239757286 PREDICTED: similar to Fc fragment of IgG binding pr...   280   1e-74
gi|239755776 PREDICTED: similar to Mucin-19 [Homo sapiens]            268   4e-71
gi|134268640 tectorin alpha precursor [Homo sapiens]                  237   1e-61
gi|16554449 zonadhesin isoform 3 [Homo sapiens]                       230   2e-59
gi|27881494 zonadhesin isoform 6 [Homo sapiens]                       230   2e-59
gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens]   160   2e-38
gi|239757284 PREDICTED: similar to Fc fragment of IgG binding pr...   147   1e-34
gi|37693519 BMP-binding endothelial regulator precursor protein ...   145   4e-34

>gi|239749989 PREDICTED: otogelin isoform 2 [Homo sapiens]
          Length = 2852

 Score = 6019 bits (15615), Expect = 0.0
 Identities = 2852/2852 (100%), Positives = 2852/2852 (100%)

Query: 1    MGDKATVVGGQQAEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECVHPAFCDCRRFNA 60
            MGDKATVVGGQQAEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECVHPAFCDCRRFNA
Sbjct: 1    MGDKATVVGGQQAEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECVHPAFCDCRRFNA 60

Query: 61   TGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQV 120
            TGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQV
Sbjct: 61   TGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQV 120

Query: 121  HNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIV 180
            HNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIV
Sbjct: 121  HNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIV 180

Query: 181  RHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHS 240
            RHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHS
Sbjct: 181  RHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHS 240

Query: 241  WQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTAS 300
            WQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTAS
Sbjct: 241  WQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTAS 300

Query: 301  CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 360
            CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC
Sbjct: 301  CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 360

Query: 361  CPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDC 420
            CPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDC
Sbjct: 361  CPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDC 420

Query: 421  NTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTL 480
            NTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTL
Sbjct: 421  NTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTL 480

Query: 481  QNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS 540
            QNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS
Sbjct: 481  QNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS 540

Query: 541  SVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPEST 600
            SVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPEST
Sbjct: 541  SVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPEST 600

Query: 601  PQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPY 660
            PQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPY
Sbjct: 601  PQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPY 660

Query: 661  FEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPC 720
            FEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPC
Sbjct: 661  FEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPC 720

Query: 721  GRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDY 780
            GRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDY
Sbjct: 721  GRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDY 780

Query: 781  PPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLL 840
            PPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLL
Sbjct: 781  PPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLL 840

Query: 841  NLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG 900
            NLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG
Sbjct: 841  NLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG 900

Query: 901  SFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSS 960
            SFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSS
Sbjct: 901  SFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSS 960

Query: 961  GMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLW 1020
            GMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLW
Sbjct: 961  GMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLW 1020

Query: 1021 DQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTL 1080
            DQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTL
Sbjct: 1021 DQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTL 1080

Query: 1081 DPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECF 1140
            DPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECF
Sbjct: 1081 DPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECF 1140

Query: 1141 CASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVG 1200
            CASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVG
Sbjct: 1141 CASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVG 1200

Query: 1201 DDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFLHVTANGSLELAK 1260
            DDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFLHVTANGSLELAK
Sbjct: 1201 DDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFLHVTANGSLELAK 1260

Query: 1261 WQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTL 1320
            WQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTL
Sbjct: 1261 WQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTL 1320

Query: 1321 FRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCPTPQVLDE 1380
            FRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCPTPQVLDE
Sbjct: 1321 FRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCPTPQVLDE 1380

Query: 1381 VTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTP 1440
            VTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTP
Sbjct: 1381 VTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTP 1440

Query: 1441 AAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAI 1500
            AAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAI
Sbjct: 1441 AAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAI 1500

Query: 1501 PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVT 1560
            PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVT
Sbjct: 1501 PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVT 1560

Query: 1561 VRGHGSLPVRTTPLQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV 1620
            VRGHGSLPVRTTPLQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV
Sbjct: 1561 VRGHGSLPVRTTPLQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV 1620

Query: 1621 PQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQ 1680
            PQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQ
Sbjct: 1621 PQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQ 1680

Query: 1681 PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSG 1740
            PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSG
Sbjct: 1681 PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSG 1740

Query: 1741 LPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHP 1800
            LPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHP
Sbjct: 1741 LPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHP 1800

Query: 1801 PTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPT 1860
            PTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPT
Sbjct: 1801 PTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPT 1860

Query: 1861 SMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLV 1920
            SMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLV
Sbjct: 1861 SMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLV 1920

Query: 1921 LLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCV 1980
            LLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCV
Sbjct: 1921 LLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCV 1980

Query: 1981 PIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCS 2040
            PIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCS
Sbjct: 1981 PIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCS 2040

Query: 2041 IFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNM 2100
            IFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNM
Sbjct: 2041 IFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNM 2100

Query: 2101 THLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLM 2160
            THLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLM
Sbjct: 2101 THLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLM 2160

Query: 2161 IVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT 2220
            IVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT
Sbjct: 2161 IVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT 2220

Query: 2221 RFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAM 2280
            RFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAM
Sbjct: 2221 RFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAM 2280

Query: 2281 CHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCV 2340
            CHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCV
Sbjct: 2281 CHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCV 2340

Query: 2341 CSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDL 2400
            CSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDL
Sbjct: 2341 CSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDL 2400

Query: 2401 GCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDS 2460
            GCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDS
Sbjct: 2401 GCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDS 2460

Query: 2461 CCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEA 2520
            CCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEA
Sbjct: 2461 CCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEA 2520

Query: 2521 LTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVP 2580
            LTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVP
Sbjct: 2521 LTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVP 2580

Query: 2581 RCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHT 2640
            RCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHT
Sbjct: 2581 RCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHT 2640

Query: 2641 SRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTT 2700
            SRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTT
Sbjct: 2641 SRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTT 2700

Query: 2701 SLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTC 2760
            SLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTC
Sbjct: 2701 SLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTC 2760

Query: 2761 KEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVG 2820
            KEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVG
Sbjct: 2761 KEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVG 2820

Query: 2821 LQRRSVQLFCATNATWVPYTVQEPTDCACQWS 2852
            LQRRSVQLFCATNATWVPYTVQEPTDCACQWS
Sbjct: 2821 LQRRSVQLFCATNATWVPYTVQEPTDCACQWS 2852


>gi|239755545 PREDICTED: otogelin isoform 1 [Homo sapiens]
          Length = 2852

 Score = 6016 bits (15608), Expect = 0.0
 Identities = 2851/2852 (99%), Positives = 2851/2852 (99%)

Query: 1    MGDKATVVGGQQAEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECVHPAFCDCRRFNA 60
            MGDKATVVGGQQAEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECVHPAFCDCRRFNA
Sbjct: 1    MGDKATVVGGQQAEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECVHPAFCDCRRFNA 60

Query: 61   TGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQV 120
            TGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQV
Sbjct: 61   TGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQV 120

Query: 121  HNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIV 180
            HNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIV
Sbjct: 121  HNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIV 180

Query: 181  RHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHS 240
            RHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHS
Sbjct: 181  RHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHS 240

Query: 241  WQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTAS 300
            WQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTAS
Sbjct: 241  WQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTAS 300

Query: 301  CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 360
            CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC
Sbjct: 301  CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 360

Query: 361  CPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDC 420
            CPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDC
Sbjct: 361  CPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDC 420

Query: 421  NTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTL 480
            NTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTL
Sbjct: 421  NTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTL 480

Query: 481  QNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS 540
            QNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS
Sbjct: 481  QNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS 540

Query: 541  SVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPEST 600
            SVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPEST
Sbjct: 541  SVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPEST 600

Query: 601  PQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPY 660
            PQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPY
Sbjct: 601  PQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPY 660

Query: 661  FEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPC 720
            FEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPC
Sbjct: 661  FEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPC 720

Query: 721  GRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDY 780
            GRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDY
Sbjct: 721  GRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDY 780

Query: 781  PPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLL 840
            PPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLL
Sbjct: 781  PPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLL 840

Query: 841  NLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG 900
            NLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG
Sbjct: 841  NLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG 900

Query: 901  SFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSS 960
            SFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSS
Sbjct: 901  SFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSS 960

Query: 961  GMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLW 1020
            GMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLW
Sbjct: 961  GMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLW 1020

Query: 1021 DQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTL 1080
            DQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTL
Sbjct: 1021 DQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTL 1080

Query: 1081 DPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECF 1140
            DPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECF
Sbjct: 1081 DPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECF 1140

Query: 1141 CASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVG 1200
            CASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVG
Sbjct: 1141 CASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVG 1200

Query: 1201 DDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFLHVTANGSLELAK 1260
            DDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFLHVTANGSLELAK
Sbjct: 1201 DDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFLHVTANGSLELAK 1260

Query: 1261 WQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTL 1320
            WQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTL
Sbjct: 1261 WQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTL 1320

Query: 1321 FRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCPTPQVLDE 1380
            FRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCPTPQVLDE
Sbjct: 1321 FRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCPTPQVLDE 1380

Query: 1381 VTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTP 1440
            VTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTP
Sbjct: 1381 VTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTP 1440

Query: 1441 AAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAI 1500
            AAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAI
Sbjct: 1441 AAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAI 1500

Query: 1501 PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVT 1560
            PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVT
Sbjct: 1501 PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVT 1560

Query: 1561 VRGHGSLPVRTTPLQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV 1620
            VRGHGSLPVRTTP QPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV
Sbjct: 1561 VRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV 1620

Query: 1621 PQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQ 1680
            PQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQ
Sbjct: 1621 PQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQ 1680

Query: 1681 PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSG 1740
            PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSG
Sbjct: 1681 PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSG 1740

Query: 1741 LPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHP 1800
            LPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHP
Sbjct: 1741 LPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHP 1800

Query: 1801 PTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPT 1860
            PTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPT
Sbjct: 1801 PTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPT 1860

Query: 1861 SMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLV 1920
            SMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLV
Sbjct: 1861 SMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLV 1920

Query: 1921 LLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCV 1980
            LLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCV
Sbjct: 1921 LLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCV 1980

Query: 1981 PIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCS 2040
            PIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCS
Sbjct: 1981 PIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCS 2040

Query: 2041 IFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNM 2100
            IFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNM
Sbjct: 2041 IFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNM 2100

Query: 2101 THLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLM 2160
            THLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLM
Sbjct: 2101 THLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLM 2160

Query: 2161 IVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT 2220
            IVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT
Sbjct: 2161 IVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT 2220

Query: 2221 RFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAM 2280
            RFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAM
Sbjct: 2221 RFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAM 2280

Query: 2281 CHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCV 2340
            CHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCV
Sbjct: 2281 CHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCV 2340

Query: 2341 CSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDL 2400
            CSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDL
Sbjct: 2341 CSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDL 2400

Query: 2401 GCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDS 2460
            GCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDS
Sbjct: 2401 GCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDS 2460

Query: 2461 CCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEA 2520
            CCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEA
Sbjct: 2461 CCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEA 2520

Query: 2521 LTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVP 2580
            LTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVP
Sbjct: 2521 LTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVP 2580

Query: 2581 RCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHT 2640
            RCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHT
Sbjct: 2581 RCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHT 2640

Query: 2641 SRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTT 2700
            SRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTT
Sbjct: 2641 SRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTT 2700

Query: 2701 SLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTC 2760
            SLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTC
Sbjct: 2701 SLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTC 2760

Query: 2761 KEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVG 2820
            KEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVG
Sbjct: 2761 KEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVG 2820

Query: 2821 LQRRSVQLFCATNATWVPYTVQEPTDCACQWS 2852
            LQRRSVQLFCATNATWVPYTVQEPTDCACQWS
Sbjct: 2821 LQRRSVQLFCATNATWVPYTVQEPTDCACQWS 2852


>gi|239744300 PREDICTED: otogelin isoform 2 [Homo sapiens]
          Length = 2852

 Score = 6016 bits (15608), Expect = 0.0
 Identities = 2851/2852 (99%), Positives = 2851/2852 (99%)

Query: 1    MGDKATVVGGQQAEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECVHPAFCDCRRFNA 60
            MGDKATVVGGQQAEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECVHPAFCDCRRFNA
Sbjct: 1    MGDKATVVGGQQAEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECVHPAFCDCRRFNA 60

Query: 61   TGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQV 120
            TGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQV
Sbjct: 61   TGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQV 120

Query: 121  HNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIV 180
            HNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIV
Sbjct: 121  HNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIV 180

Query: 181  RHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHS 240
            RHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHS
Sbjct: 181  RHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHS 240

Query: 241  WQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTAS 300
            WQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTAS
Sbjct: 241  WQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTAS 300

Query: 301  CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 360
            CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC
Sbjct: 301  CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 360

Query: 361  CPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDC 420
            CPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDC
Sbjct: 361  CPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDC 420

Query: 421  NTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTL 480
            NTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTL
Sbjct: 421  NTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTL 480

Query: 481  QNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS 540
            QNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS
Sbjct: 481  QNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS 540

Query: 541  SVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPEST 600
            SVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPEST
Sbjct: 541  SVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPEST 600

Query: 601  PQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPY 660
            PQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPY
Sbjct: 601  PQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPY 660

Query: 661  FEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPC 720
            FEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPC
Sbjct: 661  FEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPC 720

Query: 721  GRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDY 780
            GRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDY
Sbjct: 721  GRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDY 780

Query: 781  PPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLL 840
            PPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLL
Sbjct: 781  PPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLL 840

Query: 841  NLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG 900
            NLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG
Sbjct: 841  NLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG 900

Query: 901  SFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSS 960
            SFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSS
Sbjct: 901  SFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSS 960

Query: 961  GMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLW 1020
            GMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLW
Sbjct: 961  GMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLW 1020

Query: 1021 DQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTL 1080
            DQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTL
Sbjct: 1021 DQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTL 1080

Query: 1081 DPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECF 1140
            DPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECF
Sbjct: 1081 DPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECF 1140

Query: 1141 CASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVG 1200
            CASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVG
Sbjct: 1141 CASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVG 1200

Query: 1201 DDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFLHVTANGSLELAK 1260
            DDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFLHVTANGSLELAK
Sbjct: 1201 DDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFLHVTANGSLELAK 1260

Query: 1261 WQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTL 1320
            WQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTL
Sbjct: 1261 WQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTL 1320

Query: 1321 FRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCPTPQVLDE 1380
            FRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCPTPQVLDE
Sbjct: 1321 FRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCPTPQVLDE 1380

Query: 1381 VTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTP 1440
            VTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTP
Sbjct: 1381 VTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTP 1440

Query: 1441 AAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAI 1500
            AAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAI
Sbjct: 1441 AAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAI 1500

Query: 1501 PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVT 1560
            PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVT
Sbjct: 1501 PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVT 1560

Query: 1561 VRGHGSLPVRTTPLQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV 1620
            VRGHGSLPVRTTP QPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV
Sbjct: 1561 VRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV 1620

Query: 1621 PQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQ 1680
            PQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQ
Sbjct: 1621 PQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQ 1680

Query: 1681 PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSG 1740
            PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSG
Sbjct: 1681 PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSG 1740

Query: 1741 LPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHP 1800
            LPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHP
Sbjct: 1741 LPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHP 1800

Query: 1801 PTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPT 1860
            PTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPT
Sbjct: 1801 PTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPT 1860

Query: 1861 SMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLV 1920
            SMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLV
Sbjct: 1861 SMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLV 1920

Query: 1921 LLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCV 1980
            LLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCV
Sbjct: 1921 LLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCV 1980

Query: 1981 PIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCS 2040
            PIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCS
Sbjct: 1981 PIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCS 2040

Query: 2041 IFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNM 2100
            IFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNM
Sbjct: 2041 IFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNM 2100

Query: 2101 THLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLM 2160
            THLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLM
Sbjct: 2101 THLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLM 2160

Query: 2161 IVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT 2220
            IVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT
Sbjct: 2161 IVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT 2220

Query: 2221 RFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAM 2280
            RFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAM
Sbjct: 2221 RFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAM 2280

Query: 2281 CHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCV 2340
            CHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCV
Sbjct: 2281 CHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCV 2340

Query: 2341 CSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDL 2400
            CSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDL
Sbjct: 2341 CSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDL 2400

Query: 2401 GCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDS 2460
            GCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDS
Sbjct: 2401 GCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDS 2460

Query: 2461 CCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEA 2520
            CCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEA
Sbjct: 2461 CCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEA 2520

Query: 2521 LTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVP 2580
            LTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVP
Sbjct: 2521 LTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVP 2580

Query: 2581 RCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHT 2640
            RCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHT
Sbjct: 2581 RCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHT 2640

Query: 2641 SRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTT 2700
            SRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTT
Sbjct: 2641 SRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTT 2700

Query: 2701 SLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTC 2760
            SLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTC
Sbjct: 2701 SLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTC 2760

Query: 2761 KEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVG 2820
            KEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVG
Sbjct: 2761 KEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVG 2820

Query: 2821 LQRRSVQLFCATNATWVPYTVQEPTDCACQWS 2852
            LQRRSVQLFCATNATWVPYTVQEPTDCACQWS
Sbjct: 2821 LQRRSVQLFCATNATWVPYTVQEPTDCACQWS 2852


>gi|239749987 PREDICTED: otogelin isoform 1 [Homo sapiens]
          Length = 2924

 Score = 6006 bits (15580), Expect = 0.0
 Identities = 2848/2852 (99%), Positives = 2848/2852 (99%), Gaps = 1/2852 (0%)

Query: 1    MGDKATVVGGQQAEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECVHPAFCDCRRFNA 60
            MGDKATVVGGQ AEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECVHPAFCDCRRFNA
Sbjct: 74   MGDKATVVGGQ-AEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECVHPAFCDCRRFNA 132

Query: 61   TGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQV 120
            TGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQV
Sbjct: 133  TGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQV 192

Query: 121  HNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIV 180
            HNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIV
Sbjct: 193  HNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIV 252

Query: 181  RHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHS 240
            RHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHS
Sbjct: 253  RHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHS 312

Query: 241  WQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTAS 300
            WQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTAS
Sbjct: 313  WQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTAS 372

Query: 301  CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 360
            CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC
Sbjct: 373  CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 432

Query: 361  CPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDC 420
            CPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDC
Sbjct: 433  CPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDC 492

Query: 421  NTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTL 480
            NTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTL
Sbjct: 493  NTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTL 552

Query: 481  QNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS 540
            QNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS
Sbjct: 553  QNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS 612

Query: 541  SVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPEST 600
            SVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPEST
Sbjct: 613  SVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPEST 672

Query: 601  PQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPY 660
            PQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPY
Sbjct: 673  PQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPY 732

Query: 661  FEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPC 720
            FEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPC
Sbjct: 733  FEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPC 792

Query: 721  GRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDY 780
            GRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDY
Sbjct: 793  GRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDY 852

Query: 781  PPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLL 840
            PPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLL
Sbjct: 853  PPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLL 912

Query: 841  NLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG 900
            NLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG
Sbjct: 913  NLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG 972

Query: 901  SFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSS 960
            SFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSS
Sbjct: 973  SFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSS 1032

Query: 961  GMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLW 1020
            GMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLW
Sbjct: 1033 GMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLW 1092

Query: 1021 DQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTL 1080
            DQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTL
Sbjct: 1093 DQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTL 1152

Query: 1081 DPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECF 1140
            DPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECF
Sbjct: 1153 DPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECF 1212

Query: 1141 CASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVG 1200
            CASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVG
Sbjct: 1213 CASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVG 1272

Query: 1201 DDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFLHVTANGSLELAK 1260
            DDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFLHVTANGSLELAK
Sbjct: 1273 DDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFLHVTANGSLELAK 1332

Query: 1261 WQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTL 1320
            WQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTL
Sbjct: 1333 WQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTL 1392

Query: 1321 FRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCPTPQVLDE 1380
            FRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPR   CVPVCPTPQVLDE
Sbjct: 1393 FRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPRGRSCVPVCPTPQVLDE 1452

Query: 1381 VTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTP 1440
            VTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTP
Sbjct: 1453 VTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTP 1512

Query: 1441 AAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAI 1500
            AAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAI
Sbjct: 1513 AAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAI 1572

Query: 1501 PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVT 1560
            PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVT
Sbjct: 1573 PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVT 1632

Query: 1561 VRGHGSLPVRTTPLQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV 1620
            VRGHGSLPVRTTPLQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV
Sbjct: 1633 VRGHGSLPVRTTPLQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV 1692

Query: 1621 PQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQ 1680
            PQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQ
Sbjct: 1693 PQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQ 1752

Query: 1681 PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSG 1740
            PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSG
Sbjct: 1753 PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSG 1812

Query: 1741 LPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHP 1800
            LPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHP
Sbjct: 1813 LPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHP 1872

Query: 1801 PTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPT 1860
            PTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPT
Sbjct: 1873 PTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPT 1932

Query: 1861 SMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLV 1920
            SMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLV
Sbjct: 1933 SMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLV 1992

Query: 1921 LLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCV 1980
            LLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCV
Sbjct: 1993 LLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCV 2052

Query: 1981 PIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCS 2040
            PIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCS
Sbjct: 2053 PIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCS 2112

Query: 2041 IFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNM 2100
            IFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNM
Sbjct: 2113 IFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNM 2172

Query: 2101 THLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLM 2160
            THLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLM
Sbjct: 2173 THLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLM 2232

Query: 2161 IVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT 2220
            IVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT
Sbjct: 2233 IVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT 2292

Query: 2221 RFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAM 2280
            RFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAM
Sbjct: 2293 RFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAM 2352

Query: 2281 CHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCV 2340
            CHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCV
Sbjct: 2353 CHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCV 2412

Query: 2341 CSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDL 2400
            CSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDL
Sbjct: 2413 CSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDL 2472

Query: 2401 GCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDS 2460
            GCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDS
Sbjct: 2473 GCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDS 2532

Query: 2461 CCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEA 2520
            CCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEA
Sbjct: 2533 CCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEA 2592

Query: 2521 LTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVP 2580
            LTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVP
Sbjct: 2593 LTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVP 2652

Query: 2581 RCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHT 2640
            RCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHT
Sbjct: 2653 RCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHT 2712

Query: 2641 SRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTT 2700
            SRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTT
Sbjct: 2713 SRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTT 2772

Query: 2701 SLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTC 2760
            SLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTC
Sbjct: 2773 SLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTC 2832

Query: 2761 KEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVG 2820
            KEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVG
Sbjct: 2833 KEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVG 2892

Query: 2821 LQRRSVQLFCATNATWVPYTVQEPTDCACQWS 2852
            LQRRSVQLFCATNATWVPYTVQEPTDCACQWS
Sbjct: 2893 LQRRSVQLFCATNATWVPYTVQEPTDCACQWS 2924


>gi|239755543 PREDICTED: otogelin isoform 2 [Homo sapiens]
          Length = 2924

 Score = 6003 bits (15573), Expect = 0.0
 Identities = 2847/2852 (99%), Positives = 2847/2852 (99%), Gaps = 1/2852 (0%)

Query: 1    MGDKATVVGGQQAEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECVHPAFCDCRRFNA 60
            MGDKATVVGGQ AEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECVHPAFCDCRRFNA
Sbjct: 74   MGDKATVVGGQ-AEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECVHPAFCDCRRFNA 132

Query: 61   TGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQV 120
            TGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQV
Sbjct: 133  TGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQV 192

Query: 121  HNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIV 180
            HNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIV
Sbjct: 193  HNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIV 252

Query: 181  RHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHS 240
            RHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHS
Sbjct: 253  RHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHS 312

Query: 241  WQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTAS 300
            WQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTAS
Sbjct: 313  WQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTAS 372

Query: 301  CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 360
            CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC
Sbjct: 373  CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 432

Query: 361  CPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDC 420
            CPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDC
Sbjct: 433  CPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDC 492

Query: 421  NTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTL 480
            NTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTL
Sbjct: 493  NTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTL 552

Query: 481  QNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS 540
            QNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS
Sbjct: 553  QNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS 612

Query: 541  SVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPEST 600
            SVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPEST
Sbjct: 613  SVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPEST 672

Query: 601  PQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPY 660
            PQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPY
Sbjct: 673  PQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPY 732

Query: 661  FEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPC 720
            FEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPC
Sbjct: 733  FEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPC 792

Query: 721  GRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDY 780
            GRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDY
Sbjct: 793  GRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDY 852

Query: 781  PPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLL 840
            PPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLL
Sbjct: 853  PPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLL 912

Query: 841  NLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG 900
            NLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG
Sbjct: 913  NLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG 972

Query: 901  SFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSS 960
            SFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSS
Sbjct: 973  SFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSS 1032

Query: 961  GMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLW 1020
            GMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLW
Sbjct: 1033 GMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLW 1092

Query: 1021 DQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTL 1080
            DQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTL
Sbjct: 1093 DQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTL 1152

Query: 1081 DPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECF 1140
            DPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECF
Sbjct: 1153 DPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECF 1212

Query: 1141 CASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVG 1200
            CASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVG
Sbjct: 1213 CASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVG 1272

Query: 1201 DDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFLHVTANGSLELAK 1260
            DDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFLHVTANGSLELAK
Sbjct: 1273 DDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFLHVTANGSLELAK 1332

Query: 1261 WQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTL 1320
            WQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTL
Sbjct: 1333 WQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTL 1392

Query: 1321 FRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCPTPQVLDE 1380
            FRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPR   CVPVCPTPQVLDE
Sbjct: 1393 FRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPRGRSCVPVCPTPQVLDE 1452

Query: 1381 VTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTP 1440
            VTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTP
Sbjct: 1453 VTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTP 1512

Query: 1441 AAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAI 1500
            AAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAI
Sbjct: 1513 AAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAI 1572

Query: 1501 PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVT 1560
            PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVT
Sbjct: 1573 PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVT 1632

Query: 1561 VRGHGSLPVRTTPLQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV 1620
            VRGHGSLPVRTTP QPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV
Sbjct: 1633 VRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV 1692

Query: 1621 PQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQ 1680
            PQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQ
Sbjct: 1693 PQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQ 1752

Query: 1681 PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSG 1740
            PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSG
Sbjct: 1753 PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSG 1812

Query: 1741 LPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHP 1800
            LPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHP
Sbjct: 1813 LPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHP 1872

Query: 1801 PTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPT 1860
            PTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPT
Sbjct: 1873 PTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPT 1932

Query: 1861 SMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLV 1920
            SMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLV
Sbjct: 1933 SMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLV 1992

Query: 1921 LLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCV 1980
            LLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCV
Sbjct: 1993 LLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCV 2052

Query: 1981 PIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCS 2040
            PIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCS
Sbjct: 2053 PIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCS 2112

Query: 2041 IFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNM 2100
            IFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNM
Sbjct: 2113 IFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNM 2172

Query: 2101 THLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLM 2160
            THLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLM
Sbjct: 2173 THLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLM 2232

Query: 2161 IVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT 2220
            IVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT
Sbjct: 2233 IVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT 2292

Query: 2221 RFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAM 2280
            RFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAM
Sbjct: 2293 RFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAM 2352

Query: 2281 CHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCV 2340
            CHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCV
Sbjct: 2353 CHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCV 2412

Query: 2341 CSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDL 2400
            CSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDL
Sbjct: 2413 CSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDL 2472

Query: 2401 GCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDS 2460
            GCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDS
Sbjct: 2473 GCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDS 2532

Query: 2461 CCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEA 2520
            CCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEA
Sbjct: 2533 CCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEA 2592

Query: 2521 LTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVP 2580
            LTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVP
Sbjct: 2593 LTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVP 2652

Query: 2581 RCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHT 2640
            RCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHT
Sbjct: 2653 RCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHT 2712

Query: 2641 SRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTT 2700
            SRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTT
Sbjct: 2713 SRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTT 2772

Query: 2701 SLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTC 2760
            SLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTC
Sbjct: 2773 SLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTC 2832

Query: 2761 KEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVG 2820
            KEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVG
Sbjct: 2833 KEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVG 2892

Query: 2821 LQRRSVQLFCATNATWVPYTVQEPTDCACQWS 2852
            LQRRSVQLFCATNATWVPYTVQEPTDCACQWS
Sbjct: 2893 LQRRSVQLFCATNATWVPYTVQEPTDCACQWS 2924


>gi|239744298 PREDICTED: otogelin isoform 1 [Homo sapiens]
          Length = 2924

 Score = 6003 bits (15573), Expect = 0.0
 Identities = 2847/2852 (99%), Positives = 2847/2852 (99%), Gaps = 1/2852 (0%)

Query: 1    MGDKATVVGGQQAEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECVHPAFCDCRRFNA 60
            MGDKATVVGGQ AEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECVHPAFCDCRRFNA
Sbjct: 74   MGDKATVVGGQ-AEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECVHPAFCDCRRFNA 132

Query: 61   TGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQV 120
            TGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQV
Sbjct: 133  TGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQV 192

Query: 121  HNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIV 180
            HNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIV
Sbjct: 193  HNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIV 252

Query: 181  RHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHS 240
            RHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHS
Sbjct: 253  RHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHS 312

Query: 241  WQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTAS 300
            WQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTAS
Sbjct: 313  WQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTAS 372

Query: 301  CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 360
            CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC
Sbjct: 373  CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 432

Query: 361  CPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDC 420
            CPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDC
Sbjct: 433  CPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDC 492

Query: 421  NTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTL 480
            NTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTL
Sbjct: 493  NTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTL 552

Query: 481  QNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS 540
            QNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS
Sbjct: 553  QNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS 612

Query: 541  SVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPEST 600
            SVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPEST
Sbjct: 613  SVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPEST 672

Query: 601  PQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPY 660
            PQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPY
Sbjct: 673  PQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPY 732

Query: 661  FEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPC 720
            FEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPC
Sbjct: 733  FEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPC 792

Query: 721  GRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDY 780
            GRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDY
Sbjct: 793  GRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDY 852

Query: 781  PPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLL 840
            PPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLL
Sbjct: 853  PPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLL 912

Query: 841  NLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG 900
            NLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG
Sbjct: 913  NLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG 972

Query: 901  SFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSS 960
            SFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSS
Sbjct: 973  SFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSS 1032

Query: 961  GMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLW 1020
            GMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLW
Sbjct: 1033 GMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLW 1092

Query: 1021 DQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTL 1080
            DQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTL
Sbjct: 1093 DQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTL 1152

Query: 1081 DPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECF 1140
            DPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECF
Sbjct: 1153 DPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECF 1212

Query: 1141 CASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVG 1200
            CASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVG
Sbjct: 1213 CASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVG 1272

Query: 1201 DDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFLHVTANGSLELAK 1260
            DDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFLHVTANGSLELAK
Sbjct: 1273 DDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFLHVTANGSLELAK 1332

Query: 1261 WQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTL 1320
            WQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTL
Sbjct: 1333 WQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTL 1392

Query: 1321 FRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCPTPQVLDE 1380
            FRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPR   CVPVCPTPQVLDE
Sbjct: 1393 FRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPRGRSCVPVCPTPQVLDE 1452

Query: 1381 VTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTP 1440
            VTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTP
Sbjct: 1453 VTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTP 1512

Query: 1441 AAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAI 1500
            AAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAI
Sbjct: 1513 AAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAI 1572

Query: 1501 PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVT 1560
            PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVT
Sbjct: 1573 PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVT 1632

Query: 1561 VRGHGSLPVRTTPLQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV 1620
            VRGHGSLPVRTTP QPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV
Sbjct: 1633 VRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV 1692

Query: 1621 PQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQ 1680
            PQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQ
Sbjct: 1693 PQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQ 1752

Query: 1681 PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSG 1740
            PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSG
Sbjct: 1753 PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSG 1812

Query: 1741 LPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHP 1800
            LPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHP
Sbjct: 1813 LPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHP 1872

Query: 1801 PTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPT 1860
            PTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPT
Sbjct: 1873 PTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPT 1932

Query: 1861 SMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLV 1920
            SMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLV
Sbjct: 1933 SMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLV 1992

Query: 1921 LLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCV 1980
            LLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCV
Sbjct: 1993 LLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCV 2052

Query: 1981 PIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCS 2040
            PIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCS
Sbjct: 2053 PIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCS 2112

Query: 2041 IFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNM 2100
            IFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNM
Sbjct: 2113 IFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNM 2172

Query: 2101 THLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLM 2160
            THLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLM
Sbjct: 2173 THLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLM 2232

Query: 2161 IVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT 2220
            IVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT
Sbjct: 2233 IVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT 2292

Query: 2221 RFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAM 2280
            RFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAM
Sbjct: 2293 RFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAM 2352

Query: 2281 CHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCV 2340
            CHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCV
Sbjct: 2353 CHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCV 2412

Query: 2341 CSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDL 2400
            CSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDL
Sbjct: 2413 CSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDL 2472

Query: 2401 GCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDS 2460
            GCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDS
Sbjct: 2473 GCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDS 2532

Query: 2461 CCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEA 2520
            CCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEA
Sbjct: 2533 CCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEA 2592

Query: 2521 LTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVP 2580
            LTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVP
Sbjct: 2593 LTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVP 2652

Query: 2581 RCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHT 2640
            RCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHT
Sbjct: 2653 RCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHT 2712

Query: 2641 SRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTT 2700
            SRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTT
Sbjct: 2713 SRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTT 2772

Query: 2701 SLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTC 2760
            SLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTC
Sbjct: 2773 SLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTC 2832

Query: 2761 KEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVG 2820
            KEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVG
Sbjct: 2833 KEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVG 2892

Query: 2821 LQRRSVQLFCATNATWVPYTVQEPTDCACQWS 2852
            LQRRSVQLFCATNATWVPYTVQEPTDCACQWS
Sbjct: 2893 LQRRSVQLFCATNATWVPYTVQEPTDCACQWS 2924


>gi|239755901 PREDICTED: chromosome 12 open reading frame 64 [Homo
            sapiens]
          Length = 2250

 Score = 1167 bits (3019), Expect = 0.0
 Identities = 548/1385 (39%), Positives = 803/1385 (57%), Gaps = 72/1385 (5%)

Query: 39   FSCFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLS 98
            + C NG  C     CDC+ F A G RCQ++ N G  RD IC+ WGQ+H ETFDG+YYY  
Sbjct: 24   YECLNGAFCSKTGTCDCQIFQALGTRCQIIPNMGNGRDGICKTWGQYHFETFDGIYYYFP 83

Query: 99   GKGSYTLV---GRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHL-AKEVT 154
            G  SY      G  EP    +++ VHN P+C  S Y+C R++SLFF  ++EI +   E+ 
Sbjct: 84   GNCSYIFAKDCGDLEPR---YTVWVHNSPKCLGSVYSCYRSISLFFSNQEEIRIYGHEIK 140

Query: 155  HGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGN 214
              G+ + LP  +G   +++LA Y++V+    F+LAWDG S +Y+K+S +  G + GLCGN
Sbjct: 141  KNGISLTLPQTIGQIFIEKLADYILVKTTFGFSLAWDGISGIYLKLSEDHKGKSCGLCGN 200

Query: 215  NNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVY 274
             N    DD +      T+D+  F +SW  Q P+      T S    PC    P   + ++
Sbjct: 201  YNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVLTPSDFPNPCSSGMPA-FEAIF 259

Query: 275  EQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQ 334
             +C+ LL+ PF +CH Y+ P  + ASC +DLC++  D  T+CRA  EYARAC+ AG P+Q
Sbjct: 260  FKCQILLQFPFLSCHEYIDPYLYIASCVNDLCKTDDD-ETYCRAATEYARACSHAGYPIQ 318

Query: 335  GWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGG 394
             WR     CT  C + +F + +CI+CCP +C     C+ S + C+DGCYCP+GL+ ++G 
Sbjct: 319  DWRDDFPACTDKCDD-SFVHRDCISCCPPTCTFEKQCLGSNLHCLDGCYCPDGLVMDNGT 377

Query: 395  CVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDG 454
            C++   CPC FHG  Y  GS ++++C  C C  G W C+   CP +CSV GD HFTTFDG
Sbjct: 378  CISLENCPCGFHGLAYSVGSKIEQECTECVCVGGVWNCTEQDCPVQCSVVGDSHFTTFDG 437

Query: 455  RRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQA 514
            R Y+F   CQYIL K      FT+TLQ APC  N    C+QS+++IL  D  +QVTL + 
Sbjct: 438  RHYSFIGMCQYILVKGTGKDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGRG 497

Query: 515  GDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVED 574
            G +L            +   EI+ LSS+F+ ++T  G+++L+  +G R+Y+Q+   W   
Sbjct: 498  GQILTSPNQGF---NLNGIVEIQTLSSLFILLKTTFGLKILFAIDGERIYIQLTSAWKRR 554

Query: 575  TVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAAS 634
            T+GLCGTFNGN +DDFLSP G+ E TPQL  N+W+  S C   V    +DPC+++ Q   
Sbjct: 555  TLGLCGTFNGNIRDDFLSPSGMIEGTPQLHANAWRVSSTCFAPVHVPVVDPCNINQQNIG 614

Query: 635  YSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPV 694
            Y+   C V+  E+FAPC  ++SP  Y++ CR DAC+CG  CLC  LAHYA+LC +HG+P+
Sbjct: 615  YAAH-CDVIHQELFAPCHIYISPGLYYQLCRHDACKCGSSCLCNALAHYAYLCGQHGVPI 673

Query: 695  DFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPP 754
            DFR ++  CA+ C+    Y  C + C  +C  L+SPE C          D+C EGC CP 
Sbjct: 674  DFRTQISFCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCS---------DDCAEGCNCPE 724

Query: 755  DTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAA---C 811
              + +   + CVP   C CH++G  Y PG+      G C C +G + CD  A  +A   C
Sbjct: 725  GKFYEDTLNFCVPIFHCRCHYRGSVYQPGELIPTPSGLCQCSNGTVKCDELATPSAVHIC 784

Query: 812  PAGQVFVNCSDLHTDLE---LSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACF 868
            P G+ + +C     +L    ++ E TC    +N + +   PC+SGC C  G         
Sbjct: 785  PEGKEYFDCRFPDPELPAGGVNCETTCANLAMNFTCTPSSPCISGCVCAPG--------- 835

Query: 869  LPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLP 928
                                       VC+RG F CT +PC + CT YGDRHY +FDGL 
Sbjct: 836  ---------------------------VCRRGMFNCTYYPCPAVCTIYGDRHYYSFDGLE 868

Query: 929  FDFVGACKVHLVKSTSDVSFSVIVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSP 988
            +D++  C+V L+KS  D   SVI +N  C+ + ++C K + I+VG++ I  +D       
Sbjct: 869  YDYISDCQVFLIKSADDSDISVIAQNKKCFDNDIVCSKSVLISVGDTEIYLNDTPYKQKQ 928

Query: 989  ESF-LDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDL 1047
              F L++K     W+ G++ +V+FP++ IT+LWD++TT+H++ GPQW+ +L+GLCGNFD 
Sbjct: 929  SGFFLENKSTYQLWKAGYYIVVYFPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDK 988

Query: 1048 KTINEMRTPENLELTNPQEFGSSWAAVECPDTLDPRDMCVLNPLREPFAKKECSILLSEV 1107
             T N+M T  NLE+ N + FG SWA  +C    +    C  +  + P+AKKECSIL S++
Sbjct: 989  CTSNDMTTSNNLEVRNARVFGDSWALGQCESPDETIKPCEAHQNKFPYAKKECSILYSDI 1048

Query: 1108 FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCP 1167
            F  C  V+DVT F  NC  DTC C+ GGDCEC C S++AYA++CCQ G+++ WR+  +C 
Sbjct: 1049 FASCRNVIDVTSFAKNCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIHWRSSTVCS 1108

Query: 1168 YDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVGDDIVLVRTEDVAPADIVSFLLTAALYK 1227
             DC+++N+ LG+GPY L+S    G ++G       +  +    V  +    F++T  L+K
Sbjct: 1109 LDCEYYNEGLGEGPYMLASYGQSGLVLGANMTSRSVFCLPRSSVHTSLFFYFMITPGLFK 1168

Query: 1228 AKAHDPDVVSLEAADRPNFFLHVTANGSLELAKWQGRDTFQQHASFLLHRGTRQAGLVAL 1287
             K     +VSLE+A+RPN+FL+V  N +L L  W+    F + A+F  H+G    G  A 
Sbjct: 1169 EKVSSLALVSLESAERPNYFLYVHDNDTLSLELWEANSAFHRRATFFHHQGLWIPGYSAF 1228

Query: 1288 ESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTLFRLLDAKPSGAAYPICEWRYDACASPC 1347
            E  +K   F+  + + +    Y+ +E F+  + F + + + +     +CEWRY+ CA+PC
Sbjct: 1229 ELYSKKGFFIIFTDSSVKASKYDDSEEFKHSSSFSIEEIQAAVPYRKMCEWRYEPCATPC 1288

Query: 1348 FQTCRDPRAASCRDVPRVEGCVPVCPTPQVLDEVTQRCVYLEDCVEPAVWVPTEALGNET 1407
            F+TC DP A +C+ +P VEGC+P CP   +LDEVT +CVY  DC+     +PTE      
Sbjct: 1289 FKTCSDPEALACKFLPPVEGCLPYCPKNMILDEVTLKCVYPRDCIPV---IPTEP---TL 1342

Query: 1408 LPPSQ 1412
            +PP++
Sbjct: 1343 MPPAK 1347



 Score =  742 bits (1916), Expect = 0.0
 Identities = 360/923 (39%), Positives = 506/923 (54%), Gaps = 20/923 (2%)

Query: 1941 PVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVPIAEQ------DCVRHICLE 1994
            P +     P+  + P  ++ E +  +  T  +  T TT +    Q      DC ++ICL 
Sbjct: 1337 PTEPTLMPPAKPTVPMFTVWEMITPSDITVFDMLTPTTGLECEPQKFDPVYDCSQYICLN 1396

Query: 1995 GQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSH 2054
             +    N S +CP+    P CG  G  V+V  D CCP WEC CRCS+  +LS +TFDG++
Sbjct: 1397 MEWQLYNWSLNCPKDVEMPDCGFRGRPVQVNSDICCPEWECPCRCSMLSELSIITFDGNN 1456

Query: 2055 VALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNR 2114
             AL+  A YIL + P E++  H+  C             C   LN+T   H++ ++R  R
Sbjct: 1457 AALYSMASYILVRIPGEIIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLAR 1516

Query: 2115 KVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH- 2173
            KV VD   V  P S     IED+G MY+I TP+ + I+W H +G++ +          + 
Sbjct: 1517 KVEVDSIVVPLPFSSQELSIEDSGSMYVITTPAGLIIKWSHLTGIIDIHFGFRFNLSSYT 1576

Query: 2174 -GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDC 2232
             GLCGIC+ D  +DL +++G+++   ED   F++SW++  S     +   R  +C   DC
Sbjct: 1577 EGLCGICNEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTMRRPVR--NCTEHDC 1634

Query: 2233 SPCLRMVSNRTFSACHRFVPPESFCE-LWIRDTKYVQQPCVALTVYVAMCHKFHVCIEWR 2291
            S C+ +++ R F  CH  V PE FCE +WI  T +    C AL+ YVA+C+KF +CI+WR
Sbjct: 1635 SQCIDLLNRRIFIPCHDKVSPEDFCEKMWINYTYFWNYECDALSAYVALCNKFDICIQWR 1694

Query: 2292 RSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRH 2351
              DYC   C     YQ CV  CE          G      C  L E CVC  GT+LHR H
Sbjct: 1695 TPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTS---CLNLREDCVCKVGTVLHRPH 1751

Query: 2352 SALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCL 2411
            SA CIPE +CACTDS   PR  GE WN  +  C  ++C    +I+P++  C       C 
Sbjct: 1752 SAQCIPEKECACTDSEDQPRTAGEIWNGGIDECTLYKCLENGSIIPIEPDCDEEPTPVCE 1811

Query: 2412 RFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCECDP 2471
            R  EV + +  K  CC   VC C+ TLCE   PTC    +L+      SCCP Y CECDP
Sbjct: 1812 REAEVVMGIIDKWTCCSKEVCGCDTTLCETSIPTCTNSQKLIVGHSPLSCCPQYKCECDP 1871

Query: 2472 DLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEALTVHRNTTELC 2531
              C +   P CR+DQ +I  R  + CC S FC C  C   +P C +GE LTV  N+T  C
Sbjct: 1872 LKCPSISTPECREDQFMIQVRQEEPCCFSPFCVCESCTKPVPLCHDGEFLTVDLNSTHFC 1931

Query: 2532 CPLYQCVCENFRCPQ--VQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVPRCHLWEKSQ 2589
            CP Y CVCE   CP   + C     LV+     +CCP   CEC+C+ + +P C + E + 
Sbjct: 1932 CPQYYCVCEPNLCPMPLLNCAEDMNLVKENVSGQCCPTWHCECNCENLVMPTCEVGEFTA 1991

Query: 2590 LDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHTSRCTTVLDP 2649
            +D    H+ ++ CGC +Y C K  VC+ +E+ V+ PGQ++++   +  C+T  C    D 
Sbjct: 1992 ID----HNFQSDCGCIQYLCEKDDVCVFQEVSVLNPGQSMIKYLEEDFCYTIECLEEKDN 2047

Query: 2650 LTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTTSLFLPGASW 2709
             T F+ +N T V C   C+ +Q Y        CCG+C+NVSC F   NGT+ ++  G++W
Sbjct: 2048 HTGFHTLNFTLVNCSKKCDVHQVYTPSPSDYGCCGTCKNVSCKFHMENGTSVVYAVGSTW 2107

Query: 2710 IADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTCKEDGRSCKK 2769
              +C  + C  T  GA+++   + CPP NETEC    G V    EGCC+ CK + R C+K
Sbjct: 2108 HYNCTTYECVKTDEGAIILNYTMVCPPFNETECKMSEGIVKLYNEGCCKICKREERICQK 2167

Query: 2770 VTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVGLQRRSVQLF 2829
            V I+  IRK +C S +P+N+ SCDG+CPSA+IYN NI ++ RFCKCCRE G++  SV L+
Sbjct: 2168 VIIKSVIRKQDCMSQSPINVASCDGKCPSATIYNINIESHLRFCKCCRENGVRNLSVPLY 2227

Query: 2830 CATNATWVPYTVQEPTDCACQWS 2852
            C+ N T + YT+QEP DC CQW+
Sbjct: 2228 CSGNGTEIMYTLQEPIDCTCQWN 2250



 Score = 85.1 bits (209), Expect = 9e-16
 Identities = 123/516 (23%), Positives = 187/516 (36%), Gaps = 105/516 (20%)

Query: 2004 QHCPQGAAPPRCGILGLA--------------VRVGGDRCCPLWECACRCSIFPDLSFVT 2049
            ++CP       CG  GLA              V VGG   C   +C  +CS+  D  F T
Sbjct: 382  ENCP-------CGFHGLAYSVGSKIEQECTECVCVGGVWNCTEQDCPVQCSVVGDSHFTT 434

Query: 2050 FDGSHVALFKEAIYILSQSPDE---MLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQ 2106
            FDG H +      YIL +   +    +T+    C+  NLG +     CL  + +      
Sbjct: 435  FDGRHYSFIGMCQYILVKGTGKDKFTITLQKAPCEQ-NLGLV-----CLQSITL------ 482

Query: 2107 VTIDRFNRKVTVDLQPVWPPVSRYGF------RIEDTGHMYMIL-TPSDIQIQWLHSSGL 2159
            +  D FN++VT+            GF       I+    ++++L T   ++I +      
Sbjct: 483  ILEDDFNKQVTLGRGGQILTSPNQGFNLNGIVEIQTLSSLFILLKTTFGLKILFAIDGER 542

Query: 2160 MIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQ 2219
            + ++ +   K +  GLCG  +G+  +D     G + G    P    ++W+V S       
Sbjct: 543  IYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEG---TPQLHANAWRVSS------- 592

Query: 2220 TRFRPDSCATTDCSPC------------LRMVSNRTFSACHRFVPPESFCELWIRDTKYV 2267
            T F P      D  PC              ++    F+ CH ++ P  + +L   D    
Sbjct: 593  TCFAPVHVPVVD--PCNINQQNIGYAAHCDVIHQELFAPCHIYISPGLYYQLCRHDACKC 650

Query: 2268 QQPCV--ALTVYVAMCHKFHVCIEWR-RSDYCPFLCSSDSTYQACVTACEPPKTCQDGIL 2324
               C+  AL  Y  +C +  V I++R +  +C  +C     Y  C         C    +
Sbjct: 651  GSSCLCNALAHYAYLCGQHGVPIDFRTQISFCAVVCQKGMLYHHC------SSFCLHSCI 704

Query: 2325 GPLDPEHC-QVLGEGCVCSEGTILHRRHSALCIPEAKCAC--TDSMGVPRALGETWNSSL 2381
                PE C     EGC C EG   +      C+P   C C    S+  P  L  T  S L
Sbjct: 705  SLSSPEQCSDDCAEGCNCPEGK-FYEDTLNFCVPIFHCRCHYRGSVYQPGELIPT-PSGL 762

Query: 2382 SGCCQHQCQAPDTIVPVDLG-CPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCE 2440
              C     +  +   P  +  CP  +     RF +    LP     C        +T C 
Sbjct: 763  CQCSNGTVKCDELATPSAVHICPEGKEYFDCRFPDPE--LPAGGVNC--------ETTCA 812

Query: 2441 GLAP--TCRPGHRLLTHFQEDSCCPSYSCECDPDLC 2474
             LA   TC P           S C S  C C P +C
Sbjct: 813  NLAMNFTCTP----------SSPCIS-GCVCAPGVC 837



 Score = 79.7 bits (195), Expect = 4e-14
 Identities = 107/510 (20%), Positives = 172/510 (33%), Gaps = 117/510 (22%)

Query: 354  YNECIACCPASCHPRASCVDSEIACVDGC--YCPNGLIFEDGG--CVAPAEC----PCEF 405
            Y  C   C  +C    +     +  V+GC  YCP  +I ++    CV P +C    P E 
Sbjct: 1281 YEPCATPCFKTCSDPEALACKFLPPVEGCLPYCPKNMILDEVTLKCVYPRDCIPVIPTE- 1339

Query: 406  HGTLYPPGSVVKE------------------------------------DCNTCTCTSGK 429
              TL PP                                          DC+   C + +
Sbjct: 1340 -PTLMPPAKPTVPMFTVWEMITPSDITVFDMLTPTTGLECEPQKFDPVYDCSQYICLNME 1398

Query: 430  WE-------------------------------CSTAVCPAECSVTGDIHFTTFDGRRYT 458
            W+                               C    CP  CS+  ++   TFDG    
Sbjct: 1399 WQLYNWSLNCPKDVEMPDCGFRGRPVQVNSDICCPEWECPCRCSMLSELSIITFDGNNAA 1458

Query: 459  FPATCQYILAKSRSSGTFTVTLQNAPCGLNQ------DGACVQSVSVILHQDPRRQVTLT 512
              +   YIL +        +      C +NQ       G C + ++V     P  ++ + 
Sbjct: 1459 LYSMASYILVRIPGE---IIVAHIEKCSMNQAPSGRISGLCFKKLNVTT---PIHKIIVN 1512

Query: 513  QAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRW- 571
            +    +  D   +  P++     I    S+++ + T  G+ + +      + +    R+ 
Sbjct: 1513 RLARKVEVDSIVVPLPFSSQELSIEDSGSMYV-ITTPAGLIIKWSHLTGIIDIHFGFRFN 1571

Query: 572  -VEDTVGLCGTFNGNTQDDFLSPVGVPESTPQ---LFGNSWKTLSACSPLVSGSPLDPCD 627
                T GLCG  N +  DD     G   +  +   LF  SW+ +     +    P+  C 
Sbjct: 1572 LSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIGLFIESWE-IEKSFEVTMRRPVRNCT 1630

Query: 628  VHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQPCLCATLAHYAHLC 687
             H  +     Q   +L   +F PC   +SP  + E+   +         C  L+ Y  LC
Sbjct: 1631 EHDCS-----QCIDLLNRRIFIPCHDKVSPEDFCEKMWINYTYFWN-YECDALSAYVALC 1684

Query: 688  RRHGLPVDFRARLPACALSCEASKEYSPCVAPC-GRTC--QDLASPEACGVDGGDDLSRD 744
             +  + + +R     C+LSC   KEY PCV PC  RTC  Q      +C           
Sbjct: 1685 NKFDICIQWRTP-DYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSC----------L 1733

Query: 745  ECVEGCACPPDTYLD-TQADLCVPRNQCSC 773
               E C C   T L    +  C+P  +C+C
Sbjct: 1734 NLREDCVCKVGTVLHRPHSAQCIPEKECAC 1763



 Score = 65.1 bits (157), Expect = 1e-09
 Identities = 91/363 (25%), Positives = 135/363 (37%), Gaps = 64/363 (17%)

Query: 73   PERDSICRA--WGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSP 130
            PE +  CR     +  + TFDG    L    SY LV      G+   I V +  +C  + 
Sbjct: 1433 PEWECPCRCSMLSELSIITFDGNNAALYSMASYILV---RIPGE---IIVAHIEKCSMNQ 1486

Query: 131  YTCSRAVSLFFVG---EQEIH------LAKEVTHGGMRVQLPHVMGSARLQQLAGYVIVR 181
                R   L F        IH      LA++V    + V LP       ++      ++ 
Sbjct: 1487 APSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQELSIEDSGSMYVIT 1546

Query: 182  HQSAFTLAWD---GASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKL---TDDVV 235
              +   + W    G   ++      L  +T GLCG  N DP DDL   +G +    +D+ 
Sbjct: 1547 TPAGLIIKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIG 1606

Query: 236  EFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALL-RPPFDACHAYVSP 294
             F+ SW+ +   +     T   P   C + +         QC  LL R  F  CH  VSP
Sbjct: 1607 LFIESWEIEKSFE----VTMRRPVRNCTEHD-------CSQCIDLLNRRIFIPCHDKVSP 1655

Query: 295  LPFTASCTSDLCQSMGDVATW-----CRALAEYARACAQAGRPLQGWRTQLRQCTVHCKE 349
                     D C+ M    T+     C AL+ Y   C +    +Q WRT    C++ C E
Sbjct: 1656 --------EDFCEKMWINYTYFWNYECDALSAYVALCNKFDICIQ-WRTP-DYCSLSCPE 1705

Query: 350  KAFTYNECIACCPA-SC-----HPRASCVDSEIACVDGCYCPNGLIF---EDGGCVAPAE 400
                Y  C+  C A +C     +   SC++      + C C  G +        C+   E
Sbjct: 1706 -GKEYQPCVRPCEARTCLNQWFYGHTSCLNLR----EDCVCKVGTVLHRPHSAQCIPEKE 1760

Query: 401  CPC 403
            C C
Sbjct: 1761 CAC 1763



 Score = 62.8 bits (151), Expect = 5e-09
 Identities = 83/394 (21%), Positives = 137/394 (34%), Gaps = 62/394 (15%)

Query: 2007 PQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLS--------------FVTFDG 2052
            P G+ P  C       + G   C        RC I P++               F TFDG
Sbjct: 18   PSGSCPYECLNGAFCSKTGTCDCQIFQALGTRCQIIPNMGNGRDGICKTWGQYHFETFDG 77

Query: 2053 SHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNW---PPFCLVMLNMTH------L 2103
             +        YI ++           DC      +  W    P CL  +   +       
Sbjct: 78   IYYYFPGNCSYIFAK-----------DCGDLEPRYTVWVHNSPKCLGSVYSCYRSISLFF 126

Query: 2104 AHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVE 2163
            ++Q  I  +  ++  +   +  P +     IE      ++ T     + W   SG+ + +
Sbjct: 127  SNQEEIRIYGHEIKKNGISLTLPQTIGQIFIEKLADYILVKTTFGFSLAWDGISGIYL-K 185

Query: 2164 ASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSW--QVPSSLTSVGQTR 2221
             S+  K +  GLCG  +   ++D  +         ED A F +SW  Q P     V    
Sbjct: 186  LSEDHKGKSCGLCGNYNDIQSDDFIILQEDYT---EDIAMFANSWSVQTPDDTKCVLTPS 242

Query: 2222 FRPDSCATTDCSPCLRMVSNRT-------FSACHRFVPPESFCELWIRD---TKYVQQPC 2271
              P+ C++    P    +  +        F +CH ++ P  +    + D   T   +  C
Sbjct: 243  DFPNPCSSG--MPAFEAIFFKCQILLQFPFLSCHEYIDPYLYIASCVNDLCKTDDDETYC 300

Query: 2272 VALTVYVAMCHKFHVCIEWRRSDY--CPFLCSSDSTYQACVTACEPPKTCQDGILGPLDP 2329
             A T Y   C      I+  R D+  C   C     ++ C++ C P  T +   LG    
Sbjct: 301  RAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTCTFEKQCLG--SN 358

Query: 2330 EHCQVLGEGCVCSEGTILHRRHSALCIPEAKCAC 2363
             HC    +GC C +G ++    +  CI    C C
Sbjct: 359  LHCL---DGCYCPDGLVM---DNGTCISLENCPC 386



 Score = 44.3 bits (103), Expect = 0.002
 Identities = 58/283 (20%), Positives = 104/283 (36%), Gaps = 27/283 (9%)

Query: 2030 CPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLN 2089
            C  + C   C+I+ D  + +FDG       +    L +S D+     +   K      + 
Sbjct: 844  CTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLIKSADDSDISVIAQNKKCFDNDIV 903

Query: 2090 WPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPS-D 2148
                 L+ +  T +    T   + +K     Q  +   ++  +++   G+  ++  P  D
Sbjct: 904  CSKSVLISVGDTEIYLNDT--PYKQK-----QSGFFLENKSTYQLWKAGYYIVVYFPEKD 956

Query: 2149 IQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSW 2208
            I I W   + + I +     K +  GLCG  D   +ND+T  +   V  A     F DSW
Sbjct: 957  ITILWDRKTTIHI-KVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNAR---VFGDSW 1012

Query: 2209 -----QVPSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRD 2263
                 + P       +        A  +CS    ++ +  F++C   +   SF +    D
Sbjct: 1013 ALGQCESPDETIKPCEAHQNKFPYAKKECS----ILYSDIFASCRNVIDVTSFAKNCHED 1068

Query: 2264 T------KYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFLC 2300
            T         +  C ++  Y   C +  + I WR S  C   C
Sbjct: 1069 TCNCNLGGDCECLCTSIAAYAYKCCQEGISIHWRSSTVCSLDC 1111



 Score = 43.1 bits (100), Expect = 0.004
 Identities = 100/480 (20%), Positives = 164/480 (34%), Gaps = 79/480 (16%)

Query: 713  YSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCA--CPPDTYLDTQADLCVPRNQ 770
            Y PC  PC +TC D   PEA              VEGC   CP +  LD     CV    
Sbjct: 1281 YEPCATPCFKTCSD---PEALACKFLPP------VEGCLPYCPKNMILDEVTLKCVYPRD 1331

Query: 771  CS--CHFQGVDYPPGDSDIP--SLGHCHCKDGVMSCDSRAPAAACPAG-QVFVNCSDLHT 825
            C      +    PP    +P  ++        +   D   P        Q F    D   
Sbjct: 1332 CIPVIPTEPTLMPPAKPTVPMFTVWEMITPSDITVFDMLTPTTGLECEPQKFDPVYDCSQ 1391

Query: 826  DLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPG 885
             + L+ E     QL N S++          CP+ +          E   C ++G+     
Sbjct: 1392 YICLNME----WQLYNWSLN----------CPKDV----------EMPDCGFRGRPVQVN 1427

Query: 886  DQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD 945
              +  P   C C+              C+   +    TFDG            LV+   +
Sbjct: 1428 SDICCPEWECPCR--------------CSMLSELSIITFDGNNAALYSMASYILVRIPGE 1473

Query: 946  VSFSVIVE-NVNCYSSGMI---CRKFISINVGNSLIVFDDDSGNPSPESFLD----DKQE 997
            +  + I + ++N   SG I   C K +++      I+ +  +     +S +       QE
Sbjct: 1474 IIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQE 1533

Query: 998  VHTWRVGFFTLVHFPQEHITLLWDQRT---TVHVQAGPQWQGQLAGLCGNFDLKTINEMR 1054
            +     G   ++  P   I + W   T    +H            GLCG  +    +++R
Sbjct: 1534 LSIEDSGSMYVITTPAGLI-IKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLR 1592

Query: 1055 TPENLELTNPQEFGSSWAAVECPDTLDPRDMCVLNPLREPFAKKECS----ILLSEVFEI 1110
                  +TN ++ G    + E   + +   + +  P+R    + +CS    +L   +F  
Sbjct: 1593 MQNGTIITNMEDIGLFIESWEIEKSFE---VTMRRPVRN-CTEHDCSQCIDLLNRRIFIP 1648

Query: 1111 CHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDC 1170
            CH  V    F   C       +   + EC   ++SAY   C +  + + WRTP  C   C
Sbjct: 1649 CHDKVSPEDF---CEKMWINYTYFWNYEC--DALSAYVALCNKFDICIQWRTPDYCSLSC 1703


>gi|239750386 PREDICTED: chromosome 12 open reading frame 64 [Homo
            sapiens]
          Length = 2250

 Score = 1167 bits (3019), Expect = 0.0
 Identities = 548/1385 (39%), Positives = 803/1385 (57%), Gaps = 72/1385 (5%)

Query: 39   FSCFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLS 98
            + C NG  C     CDC+ F A G RCQ++ N G  RD IC+ WGQ+H ETFDG+YYY  
Sbjct: 24   YECLNGAFCSKTGTCDCQIFQALGTRCQIIPNMGNGRDGICKTWGQYHFETFDGIYYYFP 83

Query: 99   GKGSYTLV---GRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHL-AKEVT 154
            G  SY      G  EP    +++ VHN P+C  S Y+C R++SLFF  ++EI +   E+ 
Sbjct: 84   GNCSYIFAKDCGDLEPR---YTVWVHNSPKCLGSVYSCYRSISLFFSNQEEIRIYGHEIK 140

Query: 155  HGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGN 214
              G+ + LP  +G   +++LA Y++V+    F+LAWDG S +Y+K+S +  G + GLCGN
Sbjct: 141  KNGISLTLPQTIGQIFIEKLADYILVKTTFGFSLAWDGISGIYLKLSEDHKGKSCGLCGN 200

Query: 215  NNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVY 274
             N    DD +      T+D+  F +SW  Q P+      T S    PC    P   + ++
Sbjct: 201  YNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVLTPSDFPNPCSSGMPA-FEAIF 259

Query: 275  EQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQ 334
             +C+ LL+ PF +CH Y+ P  + ASC +DLC++  D  T+CRA  EYARAC+ AG P+Q
Sbjct: 260  FKCQILLQFPFLSCHEYIDPYLYIASCVNDLCKTDDD-ETYCRAATEYARACSHAGYPIQ 318

Query: 335  GWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGG 394
             WR     CT  C + +F + +CI+CCP +C     C+ S + C+DGCYCP+GL+ ++G 
Sbjct: 319  DWRDDFPACTDKCDD-SFVHRDCISCCPPTCTFEKQCLGSNLHCLDGCYCPDGLVMDNGT 377

Query: 395  CVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDG 454
            C++   CPC FHG  Y  GS ++++C  C C  G W C+   CP +CSV GD HFTTFDG
Sbjct: 378  CISLENCPCGFHGLAYSVGSKIEQECTECVCVGGVWNCTEQDCPVQCSVVGDSHFTTFDG 437

Query: 455  RRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQA 514
            R Y+F   CQYIL K      FT+TLQ APC  N    C+QS+++IL  D  +QVTL + 
Sbjct: 438  RHYSFIGMCQYILVKGTGKDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGRG 497

Query: 515  GDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVED 574
            G +L            +   EI+ LSS+F+ ++T  G+++L+  +G R+Y+Q+   W   
Sbjct: 498  GQILTSPNQGF---NLNGIVEIQTLSSLFILLKTTFGLKILFAIDGERIYIQLTSAWKRR 554

Query: 575  TVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAAS 634
            T+GLCGTFNGN +DDFLSP G+ E TPQL  N+W+  S C   V    +DPC+++ Q   
Sbjct: 555  TLGLCGTFNGNIRDDFLSPSGMIEGTPQLHANAWRVSSTCFAPVHVPVVDPCNINQQNIG 614

Query: 635  YSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPV 694
            Y+   C V+  E+FAPC  ++SP  Y++ CR DAC+CG  CLC  LAHYA+LC +HG+P+
Sbjct: 615  YAAH-CDVIHQELFAPCHIYISPGLYYQLCRHDACKCGSSCLCNALAHYAYLCGQHGVPI 673

Query: 695  DFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPP 754
            DFR ++  CA+ C+    Y  C + C  +C  L+SPE C          D+C EGC CP 
Sbjct: 674  DFRTQISFCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCS---------DDCAEGCNCPE 724

Query: 755  DTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAA---C 811
              + +   + CVP   C CH++G  Y PG+      G C C +G + CD  A  +A   C
Sbjct: 725  GKFYEDTLNFCVPIFHCRCHYRGSVYQPGELIPTPSGLCQCSNGTVKCDELATPSAVHIC 784

Query: 812  PAGQVFVNCSDLHTDLE---LSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACF 868
            P G+ + +C     +L    ++ E TC    +N + +   PC+SGC C  G         
Sbjct: 785  PEGKEYFDCRFPDPELPAGGVNCETTCANLAMNFTCTPSSPCISGCVCAPG--------- 835

Query: 869  LPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLP 928
                                       VC+RG F CT +PC + CT YGDRHY +FDGL 
Sbjct: 836  ---------------------------VCRRGMFNCTYYPCPAVCTIYGDRHYYSFDGLE 868

Query: 929  FDFVGACKVHLVKSTSDVSFSVIVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSP 988
            +D++  C+V L+KS  D   SVI +N  C+ + ++C K + I+VG++ I  +D       
Sbjct: 869  YDYISDCQVFLIKSADDSDISVIAQNKKCFDNDIVCSKSVLISVGDTEIYLNDTPYKQKQ 928

Query: 989  ESF-LDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDL 1047
              F L++K     W+ G++ +V+FP++ IT+LWD++TT+H++ GPQW+ +L+GLCGNFD 
Sbjct: 929  SGFFLENKSTYQLWKAGYYIVVYFPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDK 988

Query: 1048 KTINEMRTPENLELTNPQEFGSSWAAVECPDTLDPRDMCVLNPLREPFAKKECSILLSEV 1107
             T N+M T  NLE+ N + FG SWA  +C    +    C  +  + P+AKKECSIL S++
Sbjct: 989  CTSNDMTTSNNLEVRNARVFGDSWALGQCESPDETIKPCEAHQNKFPYAKKECSILYSDI 1048

Query: 1108 FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCP 1167
            F  C  V+DVT F  NC  DTC C+ GGDCEC C S++AYA++CCQ G+++ WR+  +C 
Sbjct: 1049 FASCRNVIDVTSFAKNCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIHWRSSTVCS 1108

Query: 1168 YDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVGDDIVLVRTEDVAPADIVSFLLTAALYK 1227
             DC+++N+ LG+GPY L+S    G ++G       +  +    V  +    F++T  L+K
Sbjct: 1109 LDCEYYNEGLGEGPYMLASYGQSGLVLGANMTSRSVFCLPRSSVHTSLFFYFMITPGLFK 1168

Query: 1228 AKAHDPDVVSLEAADRPNFFLHVTANGSLELAKWQGRDTFQQHASFLLHRGTRQAGLVAL 1287
             K     +VSLE+A+RPN+FL+V  N +L L  W+    F + A+F  H+G    G  A 
Sbjct: 1169 EKVSSLALVSLESAERPNYFLYVHDNDTLSLELWEANSAFHRRATFFHHQGLWIPGYSAF 1228

Query: 1288 ESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTLFRLLDAKPSGAAYPICEWRYDACASPC 1347
            E  +K   F+  + + +    Y+ +E F+  + F + + + +     +CEWRY+ CA+PC
Sbjct: 1229 ELYSKKGFFIIFTDSSVKASKYDDSEEFKHSSSFSIEEIQAAVPYRKMCEWRYEPCATPC 1288

Query: 1348 FQTCRDPRAASCRDVPRVEGCVPVCPTPQVLDEVTQRCVYLEDCVEPAVWVPTEALGNET 1407
            F+TC DP A +C+ +P VEGC+P CP   +LDEVT +CVY  DC+     +PTE      
Sbjct: 1289 FKTCSDPEALACKFLPPVEGCLPYCPKNMILDEVTLKCVYPRDCIPV---IPTEP---TL 1342

Query: 1408 LPPSQ 1412
            +PP++
Sbjct: 1343 MPPAK 1347



 Score =  742 bits (1916), Expect = 0.0
 Identities = 361/923 (39%), Positives = 506/923 (54%), Gaps = 20/923 (2%)

Query: 1941 PVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVPIAEQ------DCVRHICLE 1994
            P +     P+  + P  ++ E +  +  T  +  T TT +    Q      DC ++ICL 
Sbjct: 1337 PTEPTLMPPAKPTVPMFTVWEMITPSDITVFDMLTPTTGLECEPQKFDPVYDCSQYICLN 1396

Query: 1995 GQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSH 2054
             +    N S +CP+    P CG  G  V+V  D CCP WEC CRCS+  +LS +TFDG++
Sbjct: 1397 MEWQLYNWSLNCPKDVEMPDCGFRGRPVQVNSDICCPEWECPCRCSMLSELSIITFDGNN 1456

Query: 2055 VALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNR 2114
             AL+  A YIL + P E++  H+  C             C   LN+T   H++ ++R  R
Sbjct: 1457 AALYSMASYILVRIPGEIIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLAR 1516

Query: 2115 KVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH- 2173
            KV VD   V  P S     IED+G MY+I TP+ + I+W H +G++ +          + 
Sbjct: 1517 KVEVDSIVVPLPFSSQELSIEDSGSMYVITTPAGLIIKWSHLTGIIDIHFGFRFNLSSYT 1576

Query: 2174 -GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDC 2232
             GLCGIC+ D  +DL +++G+++   ED   F++SW++  S     +   R  +C   DC
Sbjct: 1577 EGLCGICNEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTMRRPVR--NCTEHDC 1634

Query: 2233 SPCLRMVSNRTFSACHRFVPPESFCE-LWIRDTKYVQQPCVALTVYVAMCHKFHVCIEWR 2291
            S C+ +++ R F  CH  V PE FCE +WI  T +    C AL+ YVA+C+KF +CI+WR
Sbjct: 1635 SQCIDLLNRRIFIPCHDKVSPEDFCEKMWINYTYFWNYECDALSAYVALCNKFDICIQWR 1694

Query: 2292 RSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRH 2351
              DYC   C     YQ CV  CE          G      C  L E CVC  GTILHR H
Sbjct: 1695 TPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTS---CLNLREDCVCKVGTILHRPH 1751

Query: 2352 SALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCL 2411
            SA CIPE +CACTDS   PR  GE WN  +  C  ++C    +I+P++  C       C 
Sbjct: 1752 SAQCIPEKECACTDSEDQPRTAGEIWNGGIDECTLYKCLENGSIIPIEPDCDEEPTPVCE 1811

Query: 2412 RFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCECDP 2471
            R  EV + +  K  CC   VC C+ TLCE   PTC    +L+      SCCP Y CECDP
Sbjct: 1812 REAEVVMGIIDKWTCCSKEVCGCDTTLCETSIPTCTNSQKLIVGHSPLSCCPQYKCECDP 1871

Query: 2472 DLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEALTVHRNTTELC 2531
              C +   P CR+DQ +I  R  + CC S FC C  C   +P C +GE LTV  N+T  C
Sbjct: 1872 LKCPSISTPECREDQFMIQVRQEEPCCFSPFCVCESCTKPVPLCHDGEFLTVDLNSTHFC 1931

Query: 2532 CPLYQCVCENFRCPQ--VQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVPRCHLWEKSQ 2589
            CP Y CVCE   CP   + C     LV+     +CCP   CEC+C+ + +P C + E + 
Sbjct: 1932 CPQYYCVCEPNLCPMPLLNCAEDMNLVKENVSGQCCPTWHCECNCENLVMPTCEVGEFTA 1991

Query: 2590 LDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHTSRCTTVLDP 2649
            +D    H+ ++ CGC +Y C K  VC+ +E+ V+ PGQ++++   +  C+T  C    D 
Sbjct: 1992 ID----HNFQSDCGCIQYLCEKDDVCVFQEVSVLNPGQSMIKYLEEDFCYTIECLEEKDN 2047

Query: 2650 LTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTTSLFLPGASW 2709
             T F+ +N T V C   C+ +Q Y        CCG+C+NVSC F   NGT+ ++  G++W
Sbjct: 2048 HTGFHTLNFTLVNCSKKCDVHQVYTPSPSDYGCCGTCKNVSCKFHMENGTSVVYAVGSTW 2107

Query: 2710 IADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTCKEDGRSCKK 2769
              +C  + C  T  GA+++   + CPP NETEC    G V    EGCC+ CK + R C+K
Sbjct: 2108 HYNCTTYECVKTDEGAIILNYTMVCPPFNETECKMNEGIVKLYNEGCCKICKREERICQK 2167

Query: 2770 VTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVGLQRRSVQLF 2829
            V I+  IRK +C S +P+N+ SCDG+CPSA+IYN NI ++ RFCKCCRE G++  SV L+
Sbjct: 2168 VIIKSVIRKQDCMSQSPINVASCDGKCPSATIYNINIESHLRFCKCCRENGVRNLSVPLY 2227

Query: 2830 CATNATWVPYTVQEPTDCACQWS 2852
            C+ N T + YT+QEP DC CQW+
Sbjct: 2228 CSGNGTEIMYTLQEPIDCTCQWN 2250



 Score = 85.1 bits (209), Expect = 9e-16
 Identities = 123/516 (23%), Positives = 187/516 (36%), Gaps = 105/516 (20%)

Query: 2004 QHCPQGAAPPRCGILGLA--------------VRVGGDRCCPLWECACRCSIFPDLSFVT 2049
            ++CP       CG  GLA              V VGG   C   +C  +CS+  D  F T
Sbjct: 382  ENCP-------CGFHGLAYSVGSKIEQECTECVCVGGVWNCTEQDCPVQCSVVGDSHFTT 434

Query: 2050 FDGSHVALFKEAIYILSQSPDE---MLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQ 2106
            FDG H +      YIL +   +    +T+    C+  NLG +     CL  + +      
Sbjct: 435  FDGRHYSFIGMCQYILVKGTGKDKFTITLQKAPCEQ-NLGLV-----CLQSITL------ 482

Query: 2107 VTIDRFNRKVTVDLQPVWPPVSRYGF------RIEDTGHMYMIL-TPSDIQIQWLHSSGL 2159
            +  D FN++VT+            GF       I+    ++++L T   ++I +      
Sbjct: 483  ILEDDFNKQVTLGRGGQILTSPNQGFNLNGIVEIQTLSSLFILLKTTFGLKILFAIDGER 542

Query: 2160 MIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQ 2219
            + ++ +   K +  GLCG  +G+  +D     G + G    P    ++W+V S       
Sbjct: 543  IYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEG---TPQLHANAWRVSS------- 592

Query: 2220 TRFRPDSCATTDCSPC------------LRMVSNRTFSACHRFVPPESFCELWIRDTKYV 2267
            T F P      D  PC              ++    F+ CH ++ P  + +L   D    
Sbjct: 593  TCFAPVHVPVVD--PCNINQQNIGYAAHCDVIHQELFAPCHIYISPGLYYQLCRHDACKC 650

Query: 2268 QQPCV--ALTVYVAMCHKFHVCIEWR-RSDYCPFLCSSDSTYQACVTACEPPKTCQDGIL 2324
               C+  AL  Y  +C +  V I++R +  +C  +C     Y  C         C    +
Sbjct: 651  GSSCLCNALAHYAYLCGQHGVPIDFRTQISFCAVVCQKGMLYHHC------SSFCLHSCI 704

Query: 2325 GPLDPEHC-QVLGEGCVCSEGTILHRRHSALCIPEAKCAC--TDSMGVPRALGETWNSSL 2381
                PE C     EGC C EG   +      C+P   C C    S+  P  L  T  S L
Sbjct: 705  SLSSPEQCSDDCAEGCNCPEGK-FYEDTLNFCVPIFHCRCHYRGSVYQPGELIPT-PSGL 762

Query: 2382 SGCCQHQCQAPDTIVPVDLG-CPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCE 2440
              C     +  +   P  +  CP  +     RF +    LP     C        +T C 
Sbjct: 763  CQCSNGTVKCDELATPSAVHICPEGKEYFDCRFPDPE--LPAGGVNC--------ETTCA 812

Query: 2441 GLAP--TCRPGHRLLTHFQEDSCCPSYSCECDPDLC 2474
             LA   TC P           S C S  C C P +C
Sbjct: 813  NLAMNFTCTP----------SSPCIS-GCVCAPGVC 837



 Score = 79.7 bits (195), Expect = 4e-14
 Identities = 107/510 (20%), Positives = 172/510 (33%), Gaps = 117/510 (22%)

Query: 354  YNECIACCPASCHPRASCVDSEIACVDGC--YCPNGLIFEDGG--CVAPAEC----PCEF 405
            Y  C   C  +C    +     +  V+GC  YCP  +I ++    CV P +C    P E 
Sbjct: 1281 YEPCATPCFKTCSDPEALACKFLPPVEGCLPYCPKNMILDEVTLKCVYPRDCIPVIPTE- 1339

Query: 406  HGTLYPPGSVVKE------------------------------------DCNTCTCTSGK 429
              TL PP                                          DC+   C + +
Sbjct: 1340 -PTLMPPAKPTVPMFTVWEMITPSDITVFDMLTPTTGLECEPQKFDPVYDCSQYICLNME 1398

Query: 430  WE-------------------------------CSTAVCPAECSVTGDIHFTTFDGRRYT 458
            W+                               C    CP  CS+  ++   TFDG    
Sbjct: 1399 WQLYNWSLNCPKDVEMPDCGFRGRPVQVNSDICCPEWECPCRCSMLSELSIITFDGNNAA 1458

Query: 459  FPATCQYILAKSRSSGTFTVTLQNAPCGLNQ------DGACVQSVSVILHQDPRRQVTLT 512
              +   YIL +        +      C +NQ       G C + ++V     P  ++ + 
Sbjct: 1459 LYSMASYILVRIPGE---IIVAHIEKCSMNQAPSGRISGLCFKKLNVTT---PIHKIIVN 1512

Query: 513  QAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRW- 571
            +    +  D   +  P++     I    S+++ + T  G+ + +      + +    R+ 
Sbjct: 1513 RLARKVEVDSIVVPLPFSSQELSIEDSGSMYV-ITTPAGLIIKWSHLTGIIDIHFGFRFN 1571

Query: 572  -VEDTVGLCGTFNGNTQDDFLSPVGVPESTPQ---LFGNSWKTLSACSPLVSGSPLDPCD 627
                T GLCG  N +  DD     G   +  +   LF  SW+ +     +    P+  C 
Sbjct: 1572 LSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIGLFIESWE-IEKSFEVTMRRPVRNCT 1630

Query: 628  VHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQPCLCATLAHYAHLC 687
             H  +     Q   +L   +F PC   +SP  + E+   +         C  L+ Y  LC
Sbjct: 1631 EHDCS-----QCIDLLNRRIFIPCHDKVSPEDFCEKMWINYTYFWN-YECDALSAYVALC 1684

Query: 688  RRHGLPVDFRARLPACALSCEASKEYSPCVAPC-GRTC--QDLASPEACGVDGGDDLSRD 744
             +  + + +R     C+LSC   KEY PCV PC  RTC  Q      +C           
Sbjct: 1685 NKFDICIQWRTP-DYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSC----------L 1733

Query: 745  ECVEGCACPPDTYLD-TQADLCVPRNQCSC 773
               E C C   T L    +  C+P  +C+C
Sbjct: 1734 NLREDCVCKVGTILHRPHSAQCIPEKECAC 1763



 Score = 65.5 bits (158), Expect = 7e-10
 Identities = 92/363 (25%), Positives = 135/363 (37%), Gaps = 64/363 (17%)

Query: 73   PERDSICRA--WGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSP 130
            PE +  CR     +  + TFDG    L    SY LV      G+   I V +  +C  + 
Sbjct: 1433 PEWECPCRCSMLSELSIITFDGNNAALYSMASYILV---RIPGE---IIVAHIEKCSMNQ 1486

Query: 131  YTCSRAVSLFFVG---EQEIH------LAKEVTHGGMRVQLPHVMGSARLQQLAGYVIVR 181
                R   L F        IH      LA++V    + V LP       ++      ++ 
Sbjct: 1487 APSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQELSIEDSGSMYVIT 1546

Query: 182  HQSAFTLAWD---GASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKL---TDDVV 235
              +   + W    G   ++      L  +T GLCG  N DP DDL   +G +    +D+ 
Sbjct: 1547 TPAGLIIKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIG 1606

Query: 236  EFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALL-RPPFDACHAYVSP 294
             F+ SW+ +   +     T   P   C + +         QC  LL R  F  CH  VSP
Sbjct: 1607 LFIESWEIEKSFE----VTMRRPVRNCTEHD-------CSQCIDLLNRRIFIPCHDKVSP 1655

Query: 295  LPFTASCTSDLCQSMGDVATW-----CRALAEYARACAQAGRPLQGWRTQLRQCTVHCKE 349
                     D C+ M    T+     C AL+ Y   C +    +Q WRT    C++ C E
Sbjct: 1656 --------EDFCEKMWINYTYFWNYECDALSAYVALCNKFDICIQ-WRTP-DYCSLSCPE 1705

Query: 350  KAFTYNECIACCPA-SC-----HPRASCVDSEIACVDGCYCPNGLIF---EDGGCVAPAE 400
                Y  C+  C A +C     +   SC++      + C C  G I        C+   E
Sbjct: 1706 -GKEYQPCVRPCEARTCLNQWFYGHTSCLNLR----EDCVCKVGTILHRPHSAQCIPEKE 1760

Query: 401  CPC 403
            C C
Sbjct: 1761 CAC 1763



 Score = 62.8 bits (151), Expect = 5e-09
 Identities = 83/394 (21%), Positives = 137/394 (34%), Gaps = 62/394 (15%)

Query: 2007 PQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLS--------------FVTFDG 2052
            P G+ P  C       + G   C        RC I P++               F TFDG
Sbjct: 18   PSGSCPYECLNGAFCSKTGTCDCQIFQALGTRCQIIPNMGNGRDGICKTWGQYHFETFDG 77

Query: 2053 SHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNW---PPFCLVMLNMTH------L 2103
             +        YI ++           DC      +  W    P CL  +   +       
Sbjct: 78   IYYYFPGNCSYIFAK-----------DCGDLEPRYTVWVHNSPKCLGSVYSCYRSISLFF 126

Query: 2104 AHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVE 2163
            ++Q  I  +  ++  +   +  P +     IE      ++ T     + W   SG+ + +
Sbjct: 127  SNQEEIRIYGHEIKKNGISLTLPQTIGQIFIEKLADYILVKTTFGFSLAWDGISGIYL-K 185

Query: 2164 ASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSW--QVPSSLTSVGQTR 2221
             S+  K +  GLCG  +   ++D  +         ED A F +SW  Q P     V    
Sbjct: 186  LSEDHKGKSCGLCGNYNDIQSDDFIILQEDYT---EDIAMFANSWSVQTPDDTKCVLTPS 242

Query: 2222 FRPDSCATTDCSPCLRMVSNRT-------FSACHRFVPPESFCELWIRD---TKYVQQPC 2271
              P+ C++    P    +  +        F +CH ++ P  +    + D   T   +  C
Sbjct: 243  DFPNPCSSG--MPAFEAIFFKCQILLQFPFLSCHEYIDPYLYIASCVNDLCKTDDDETYC 300

Query: 2272 VALTVYVAMCHKFHVCIEWRRSDY--CPFLCSSDSTYQACVTACEPPKTCQDGILGPLDP 2329
             A T Y   C      I+  R D+  C   C     ++ C++ C P  T +   LG    
Sbjct: 301  RAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTCTFEKQCLG--SN 358

Query: 2330 EHCQVLGEGCVCSEGTILHRRHSALCIPEAKCAC 2363
             HC    +GC C +G ++    +  CI    C C
Sbjct: 359  LHCL---DGCYCPDGLVM---DNGTCISLENCPC 386



 Score = 44.3 bits (103), Expect = 0.002
 Identities = 58/283 (20%), Positives = 104/283 (36%), Gaps = 27/283 (9%)

Query: 2030 CPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLN 2089
            C  + C   C+I+ D  + +FDG       +    L +S D+     +   K      + 
Sbjct: 844  CTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLIKSADDSDISVIAQNKKCFDNDIV 903

Query: 2090 WPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPS-D 2148
                 L+ +  T +    T   + +K     Q  +   ++  +++   G+  ++  P  D
Sbjct: 904  CSKSVLISVGDTEIYLNDT--PYKQK-----QSGFFLENKSTYQLWKAGYYIVVYFPEKD 956

Query: 2149 IQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSW 2208
            I I W   + + I +     K +  GLCG  D   +ND+T  +   V  A     F DSW
Sbjct: 957  ITILWDRKTTIHI-KVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNAR---VFGDSW 1012

Query: 2209 -----QVPSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRD 2263
                 + P       +        A  +CS    ++ +  F++C   +   SF +    D
Sbjct: 1013 ALGQCESPDETIKPCEAHQNKFPYAKKECS----ILYSDIFASCRNVIDVTSFAKNCHED 1068

Query: 2264 T------KYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFLC 2300
            T         +  C ++  Y   C +  + I WR S  C   C
Sbjct: 1069 TCNCNLGGDCECLCTSIAAYAYKCCQEGISIHWRSSTVCSLDC 1111



 Score = 43.1 bits (100), Expect = 0.004
 Identities = 100/480 (20%), Positives = 164/480 (34%), Gaps = 79/480 (16%)

Query: 713  YSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCA--CPPDTYLDTQADLCVPRNQ 770
            Y PC  PC +TC D   PEA              VEGC   CP +  LD     CV    
Sbjct: 1281 YEPCATPCFKTCSD---PEALACKFLPP------VEGCLPYCPKNMILDEVTLKCVYPRD 1331

Query: 771  CS--CHFQGVDYPPGDSDIP--SLGHCHCKDGVMSCDSRAPAAACPAG-QVFVNCSDLHT 825
            C      +    PP    +P  ++        +   D   P        Q F    D   
Sbjct: 1332 CIPVIPTEPTLMPPAKPTVPMFTVWEMITPSDITVFDMLTPTTGLECEPQKFDPVYDCSQ 1391

Query: 826  DLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPG 885
             + L+ E     QL N S++          CP+ +          E   C ++G+     
Sbjct: 1392 YICLNME----WQLYNWSLN----------CPKDV----------EMPDCGFRGRPVQVN 1427

Query: 886  DQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD 945
              +  P   C C+              C+   +    TFDG            LV+   +
Sbjct: 1428 SDICCPEWECPCR--------------CSMLSELSIITFDGNNAALYSMASYILVRIPGE 1473

Query: 946  VSFSVIVE-NVNCYSSGMI---CRKFISINVGNSLIVFDDDSGNPSPESFLD----DKQE 997
            +  + I + ++N   SG I   C K +++      I+ +  +     +S +       QE
Sbjct: 1474 IIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQE 1533

Query: 998  VHTWRVGFFTLVHFPQEHITLLWDQRT---TVHVQAGPQWQGQLAGLCGNFDLKTINEMR 1054
            +     G   ++  P   I + W   T    +H            GLCG  +    +++R
Sbjct: 1534 LSIEDSGSMYVITTPAGLI-IKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLR 1592

Query: 1055 TPENLELTNPQEFGSSWAAVECPDTLDPRDMCVLNPLREPFAKKECS----ILLSEVFEI 1110
                  +TN ++ G    + E   + +   + +  P+R    + +CS    +L   +F  
Sbjct: 1593 MQNGTIITNMEDIGLFIESWEIEKSFE---VTMRRPVRN-CTEHDCSQCIDLLNRRIFIP 1648

Query: 1111 CHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDC 1170
            CH  V    F   C       +   + EC   ++SAY   C +  + + WRTP  C   C
Sbjct: 1649 CHDKVSPEDF---CEKMWINYTYFWNYEC--DALSAYVALCNKFDICIQWRTPDYCSLSC 1703


>gi|239744688 PREDICTED: hypothetical protein LOC283310 [Homo sapiens]
          Length = 2250

 Score = 1167 bits (3019), Expect = 0.0
 Identities = 548/1385 (39%), Positives = 803/1385 (57%), Gaps = 72/1385 (5%)

Query: 39   FSCFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLS 98
            + C NG  C     CDC+ F A G RCQ++ N G  RD IC+ WGQ+H ETFDG+YYY  
Sbjct: 24   YECLNGAFCSKTGTCDCQIFQALGTRCQIIPNMGNGRDGICKTWGQYHFETFDGIYYYFP 83

Query: 99   GKGSYTLV---GRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHL-AKEVT 154
            G  SY      G  EP    +++ VHN P+C  S Y+C R++SLFF  ++EI +   E+ 
Sbjct: 84   GNCSYIFAKDCGDLEPR---YTVWVHNSPKCLGSVYSCYRSISLFFSNQEEIRIYGHEIK 140

Query: 155  HGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGN 214
              G+ + LP  +G   +++LA Y++V+    F+LAWDG S +Y+K+S +  G + GLCGN
Sbjct: 141  KNGISLTLPQTIGQIFIEKLADYILVKTTFGFSLAWDGISGIYLKLSEDHKGKSCGLCGN 200

Query: 215  NNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVY 274
             N    DD +      T+D+  F +SW  Q P+      T S    PC    P   + ++
Sbjct: 201  YNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVLTPSDFPNPCSSGMPA-FEAIF 259

Query: 275  EQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQ 334
             +C+ LL+ PF +CH Y+ P  + ASC +DLC++  D  T+CRA  EYARAC+ AG P+Q
Sbjct: 260  FKCQILLQFPFLSCHEYIDPYLYIASCVNDLCKTDDD-ETYCRAATEYARACSHAGYPIQ 318

Query: 335  GWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGG 394
             WR     CT  C + +F + +CI+CCP +C     C+ S + C+DGCYCP+GL+ ++G 
Sbjct: 319  DWRDDFPACTDKCDD-SFVHRDCISCCPPTCTFEKQCLGSNLHCLDGCYCPDGLVMDNGT 377

Query: 395  CVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDG 454
            C++   CPC FHG  Y  GS ++++C  C C  G W C+   CP +CSV GD HFTTFDG
Sbjct: 378  CISLENCPCGFHGLAYSVGSKIEQECTECVCVGGVWNCTEQDCPVQCSVVGDSHFTTFDG 437

Query: 455  RRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQA 514
            R Y+F   CQYIL K      FT+TLQ APC  N    C+QS+++IL  D  +QVTL + 
Sbjct: 438  RHYSFIGMCQYILVKGTGKDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGRG 497

Query: 515  GDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVED 574
            G +L            +   EI+ LSS+F+ ++T  G+++L+  +G R+Y+Q+   W   
Sbjct: 498  GQILTSPNQGF---NLNGIVEIQTLSSLFILLKTTFGLKILFAIDGERIYIQLTSAWKRR 554

Query: 575  TVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAAS 634
            T+GLCGTFNGN +DDFLSP G+ E TPQL  N+W+  S C   V    +DPC+++ Q   
Sbjct: 555  TLGLCGTFNGNIRDDFLSPSGMIEGTPQLHANAWRVSSTCFAPVHVPVVDPCNINQQNIG 614

Query: 635  YSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPV 694
            Y+   C V+  E+FAPC  ++SP  Y++ CR DAC+CG  CLC  LAHYA+LC +HG+P+
Sbjct: 615  YAAH-CDVIHQELFAPCHIYISPGLYYQLCRHDACKCGSSCLCNALAHYAYLCGQHGVPI 673

Query: 695  DFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPP 754
            DFR ++  CA+ C+    Y  C + C  +C  L+SPE C          D+C EGC CP 
Sbjct: 674  DFRTQISFCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCS---------DDCAEGCNCPE 724

Query: 755  DTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAA---C 811
              + +   + CVP   C CH++G  Y PG+      G C C +G + CD  A  +A   C
Sbjct: 725  GKFYEDTLNFCVPIFHCRCHYRGSVYQPGELIPTPSGLCQCSNGTVKCDELATPSAVHIC 784

Query: 812  PAGQVFVNCSDLHTDLE---LSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACF 868
            P G+ + +C     +L    ++ E TC    +N + +   PC+SGC C  G         
Sbjct: 785  PEGKEYFDCRFPDPELPAGGVNCETTCANLAMNFTCTPSSPCISGCVCAPG--------- 835

Query: 869  LPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLP 928
                                       VC+RG F CT +PC + CT YGDRHY +FDGL 
Sbjct: 836  ---------------------------VCRRGMFNCTYYPCPAVCTIYGDRHYYSFDGLE 868

Query: 929  FDFVGACKVHLVKSTSDVSFSVIVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSP 988
            +D++  C+V L+KS  D   SVI +N  C+ + ++C K + I+VG++ I  +D       
Sbjct: 869  YDYISDCQVFLIKSADDSDISVIAQNKKCFDNDIVCSKSVLISVGDTEIYLNDTPYKQKQ 928

Query: 989  ESF-LDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDL 1047
              F L++K     W+ G++ +V+FP++ IT+LWD++TT+H++ GPQW+ +L+GLCGNFD 
Sbjct: 929  SGFFLENKSTYQLWKAGYYIVVYFPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDK 988

Query: 1048 KTINEMRTPENLELTNPQEFGSSWAAVECPDTLDPRDMCVLNPLREPFAKKECSILLSEV 1107
             T N+M T  NLE+ N + FG SWA  +C    +    C  +  + P+AKKECSIL S++
Sbjct: 989  CTSNDMTTSNNLEVRNARVFGDSWALGQCESPDETIKPCEAHQNKFPYAKKECSILYSDI 1048

Query: 1108 FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCP 1167
            F  C  V+DVT F  NC  DTC C+ GGDCEC C S++AYA++CCQ G+++ WR+  +C 
Sbjct: 1049 FASCRNVIDVTSFAKNCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIHWRSSTVCS 1108

Query: 1168 YDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVGDDIVLVRTEDVAPADIVSFLLTAALYK 1227
             DC+++N+ LG+GPY L+S    G ++G       +  +    V  +    F++T  L+K
Sbjct: 1109 LDCEYYNEGLGEGPYMLASYGQSGLVLGANMTSRSVFCLPRSSVHTSLFFYFMITPGLFK 1168

Query: 1228 AKAHDPDVVSLEAADRPNFFLHVTANGSLELAKWQGRDTFQQHASFLLHRGTRQAGLVAL 1287
             K     +VSLE+A+RPN+FL+V  N +L L  W+    F + A+F  H+G    G  A 
Sbjct: 1169 EKVSSLALVSLESAERPNYFLYVHDNDTLSLELWEANSAFHRRATFFHHQGLWIPGYSAF 1228

Query: 1288 ESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTLFRLLDAKPSGAAYPICEWRYDACASPC 1347
            E  +K   F+  + + +    Y+ +E F+  + F + + + +     +CEWRY+ CA+PC
Sbjct: 1229 ELYSKKGFFIIFTDSSVKASKYDDSEEFKHSSSFSIEEIQAAVPYRKMCEWRYEPCATPC 1288

Query: 1348 FQTCRDPRAASCRDVPRVEGCVPVCPTPQVLDEVTQRCVYLEDCVEPAVWVPTEALGNET 1407
            F+TC DP A +C+ +P VEGC+P CP   +LDEVT +CVY  DC+     +PTE      
Sbjct: 1289 FKTCSDPEALACKFLPPVEGCLPYCPKNMILDEVTLKCVYPRDCIPV---IPTEP---TL 1342

Query: 1408 LPPSQ 1412
            +PP++
Sbjct: 1343 MPPAK 1347



 Score =  740 bits (1910), Expect = 0.0
 Identities = 360/923 (39%), Positives = 505/923 (54%), Gaps = 20/923 (2%)

Query: 1941 PVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVPIAEQ------DCVRHICLE 1994
            P +     P+  + P  ++ E +  +  T  +  T TT +    Q      DC ++ICL 
Sbjct: 1337 PTEPTLMPPAKPTVPMFTVWEMITPSDITVFDMLTPTTGLECEPQKFDPVYDCSQYICLN 1396

Query: 1995 GQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSH 2054
             +    N S +CP+    P CG  G  V+V  D CCP WEC CRCS+  +LS +TFDG++
Sbjct: 1397 MEWQLYNWSLNCPKDVEMPDCGFRGRPVQVNSDICCPEWECPCRCSMLSELSIITFDGNN 1456

Query: 2055 VALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNR 2114
             AL+  A YIL + P E++  H+  C             C   LN+T   H++ ++R  R
Sbjct: 1457 AALYSMASYILVRIPGEIIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLAR 1516

Query: 2115 KVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH- 2173
            KV VD   V  P S     IED+G MY+I TP+ + I+W H +G++ +          + 
Sbjct: 1517 KVEVDSIVVPLPFSSQELSIEDSGSMYVITTPAGLIIKWSHLTGIIDIHFGFRFNLSSYT 1576

Query: 2174 -GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDC 2232
             GLCGIC+ D  +DL +++G+++   ED   F++SW++  S     +   R  +C   DC
Sbjct: 1577 EGLCGICNEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTMRRPVR--NCTEHDC 1634

Query: 2233 SPCLRMVSNRTFSACHRFVPPESFCE-LWIRDTKYVQQPCVALTVYVAMCHKFHVCIEWR 2291
            S C+ +++ R F  CH  V PE FCE +WI  T +    C AL+ YVA+C+KF +CI+WR
Sbjct: 1635 SQCIDLLNRRIFIPCHDKVSPEDFCEKMWINYTYFWNYECDALSAYVALCNKFDICIQWR 1694

Query: 2292 RSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRH 2351
              DYC   C     YQ CV  CE          G      C  L E CVC  GTILHR H
Sbjct: 1695 TPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTS---CLNLREDCVCKVGTILHRPH 1751

Query: 2352 SALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCL 2411
            SA CIPE +CACTDS   PR  GE WN  +  C  ++C    +I+P++  C       C 
Sbjct: 1752 SAQCIPEKECACTDSEDQPRTAGEIWNGGIDECTLYKCLENGSIIPIEPDCDEEPTPVCE 1811

Query: 2412 RFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCECDP 2471
            R  EV + +  K  CC   VC C+ TLCE   PTC    +L+      SCCP Y CECDP
Sbjct: 1812 REAEVVMGIIDKWTCCSKEVCGCDTTLCETSIPTCTNSQKLIVGHSPLSCCPQYKCECDP 1871

Query: 2472 DLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEALTVHRNTTELC 2531
              C +   P CR+DQ +I  R  + CC S FC C  C   +P C +GE LTV  N+T  C
Sbjct: 1872 LKCPSISTPECREDQFMIQVRQEEPCCFSPFCVCESCTKPVPLCHDGEFLTVDLNSTHFC 1931

Query: 2532 CPLYQCVCENFRCPQ--VQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVPRCHLWEKSQ 2589
            CP Y CVCE   CP   + C     LV+     +CCP   CEC+C+ + +P C + E + 
Sbjct: 1932 CPQYYCVCEPNLCPMPLLNCAEDMNLVKENVSGQCCPTWHCECNCENLIMPTCEVGEFTA 1991

Query: 2590 LDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHTSRCTTVLDP 2649
            +D    H+ ++ CGC +Y C K  VC+ +E+ V+ PGQ++++   +  C+   C    D 
Sbjct: 1992 ID----HNFQSDCGCIQYLCEKDDVCVFQEVSVLNPGQSMIKYLEEDFCYAIECLEEKDN 2047

Query: 2650 LTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTTSLFLPGASW 2709
             T F+ +N T V C   C+ +Q Y        CCG+C+NVSC F   NGT+ ++  G++W
Sbjct: 2048 HTGFHTLNFTLVNCSKKCDVHQVYTPSPSDYGCCGTCKNVSCKFHMENGTSVVYAVGSTW 2107

Query: 2710 IADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTCKEDGRSCKK 2769
              +C  + C  T  GA+++   + CPP NETEC    G V    EGCC+ CK + R C+K
Sbjct: 2108 HYNCTTYECVKTDEGAIILNYTMVCPPFNETECKMNEGIVKLYNEGCCKICKREERICQK 2167

Query: 2770 VTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVGLQRRSVQLF 2829
            V I+  IRK +C S +P+N+ SCDG+CPSA+IYN NI ++ RFCKCCRE G++  SV L+
Sbjct: 2168 VIIKSVIRKQDCMSQSPINVASCDGKCPSATIYNINIESHLRFCKCCRENGVRNLSVPLY 2227

Query: 2830 CATNATWVPYTVQEPTDCACQWS 2852
            C+ N T + YT+QEP DC CQW+
Sbjct: 2228 CSGNGTEIMYTLQEPIDCTCQWN 2250



 Score = 85.1 bits (209), Expect = 9e-16
 Identities = 123/516 (23%), Positives = 187/516 (36%), Gaps = 105/516 (20%)

Query: 2004 QHCPQGAAPPRCGILGLA--------------VRVGGDRCCPLWECACRCSIFPDLSFVT 2049
            ++CP       CG  GLA              V VGG   C   +C  +CS+  D  F T
Sbjct: 382  ENCP-------CGFHGLAYSVGSKIEQECTECVCVGGVWNCTEQDCPVQCSVVGDSHFTT 434

Query: 2050 FDGSHVALFKEAIYILSQSPDE---MLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQ 2106
            FDG H +      YIL +   +    +T+    C+  NLG +     CL  + +      
Sbjct: 435  FDGRHYSFIGMCQYILVKGTGKDKFTITLQKAPCEQ-NLGLV-----CLQSITL------ 482

Query: 2107 VTIDRFNRKVTVDLQPVWPPVSRYGF------RIEDTGHMYMIL-TPSDIQIQWLHSSGL 2159
            +  D FN++VT+            GF       I+    ++++L T   ++I +      
Sbjct: 483  ILEDDFNKQVTLGRGGQILTSPNQGFNLNGIVEIQTLSSLFILLKTTFGLKILFAIDGER 542

Query: 2160 MIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQ 2219
            + ++ +   K +  GLCG  +G+  +D     G + G    P    ++W+V S       
Sbjct: 543  IYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEG---TPQLHANAWRVSS------- 592

Query: 2220 TRFRPDSCATTDCSPC------------LRMVSNRTFSACHRFVPPESFCELWIRDTKYV 2267
            T F P      D  PC              ++    F+ CH ++ P  + +L   D    
Sbjct: 593  TCFAPVHVPVVD--PCNINQQNIGYAAHCDVIHQELFAPCHIYISPGLYYQLCRHDACKC 650

Query: 2268 QQPCV--ALTVYVAMCHKFHVCIEWR-RSDYCPFLCSSDSTYQACVTACEPPKTCQDGIL 2324
               C+  AL  Y  +C +  V I++R +  +C  +C     Y  C         C    +
Sbjct: 651  GSSCLCNALAHYAYLCGQHGVPIDFRTQISFCAVVCQKGMLYHHC------SSFCLHSCI 704

Query: 2325 GPLDPEHC-QVLGEGCVCSEGTILHRRHSALCIPEAKCAC--TDSMGVPRALGETWNSSL 2381
                PE C     EGC C EG   +      C+P   C C    S+  P  L  T  S L
Sbjct: 705  SLSSPEQCSDDCAEGCNCPEGK-FYEDTLNFCVPIFHCRCHYRGSVYQPGELIPT-PSGL 762

Query: 2382 SGCCQHQCQAPDTIVPVDLG-CPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCE 2440
              C     +  +   P  +  CP  +     RF +    LP     C        +T C 
Sbjct: 763  CQCSNGTVKCDELATPSAVHICPEGKEYFDCRFPDPE--LPAGGVNC--------ETTCA 812

Query: 2441 GLAP--TCRPGHRLLTHFQEDSCCPSYSCECDPDLC 2474
             LA   TC P           S C S  C C P +C
Sbjct: 813  NLAMNFTCTP----------SSPCIS-GCVCAPGVC 837



 Score = 79.7 bits (195), Expect = 4e-14
 Identities = 107/510 (20%), Positives = 172/510 (33%), Gaps = 117/510 (22%)

Query: 354  YNECIACCPASCHPRASCVDSEIACVDGC--YCPNGLIFEDGG--CVAPAEC----PCEF 405
            Y  C   C  +C    +     +  V+GC  YCP  +I ++    CV P +C    P E 
Sbjct: 1281 YEPCATPCFKTCSDPEALACKFLPPVEGCLPYCPKNMILDEVTLKCVYPRDCIPVIPTE- 1339

Query: 406  HGTLYPPGSVVKE------------------------------------DCNTCTCTSGK 429
              TL PP                                          DC+   C + +
Sbjct: 1340 -PTLMPPAKPTVPMFTVWEMITPSDITVFDMLTPTTGLECEPQKFDPVYDCSQYICLNME 1398

Query: 430  WE-------------------------------CSTAVCPAECSVTGDIHFTTFDGRRYT 458
            W+                               C    CP  CS+  ++   TFDG    
Sbjct: 1399 WQLYNWSLNCPKDVEMPDCGFRGRPVQVNSDICCPEWECPCRCSMLSELSIITFDGNNAA 1458

Query: 459  FPATCQYILAKSRSSGTFTVTLQNAPCGLNQ------DGACVQSVSVILHQDPRRQVTLT 512
              +   YIL +        +      C +NQ       G C + ++V     P  ++ + 
Sbjct: 1459 LYSMASYILVRIPGE---IIVAHIEKCSMNQAPSGRISGLCFKKLNVTT---PIHKIIVN 1512

Query: 513  QAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRW- 571
            +    +  D   +  P++     I    S+++ + T  G+ + +      + +    R+ 
Sbjct: 1513 RLARKVEVDSIVVPLPFSSQELSIEDSGSMYV-ITTPAGLIIKWSHLTGIIDIHFGFRFN 1571

Query: 572  -VEDTVGLCGTFNGNTQDDFLSPVGVPESTPQ---LFGNSWKTLSACSPLVSGSPLDPCD 627
                T GLCG  N +  DD     G   +  +   LF  SW+ +     +    P+  C 
Sbjct: 1572 LSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIGLFIESWE-IEKSFEVTMRRPVRNCT 1630

Query: 628  VHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQPCLCATLAHYAHLC 687
             H  +     Q   +L   +F PC   +SP  + E+   +         C  L+ Y  LC
Sbjct: 1631 EHDCS-----QCIDLLNRRIFIPCHDKVSPEDFCEKMWINYTYFWN-YECDALSAYVALC 1684

Query: 688  RRHGLPVDFRARLPACALSCEASKEYSPCVAPC-GRTC--QDLASPEACGVDGGDDLSRD 744
             +  + + +R     C+LSC   KEY PCV PC  RTC  Q      +C           
Sbjct: 1685 NKFDICIQWRTP-DYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSC----------L 1733

Query: 745  ECVEGCACPPDTYLD-TQADLCVPRNQCSC 773
               E C C   T L    +  C+P  +C+C
Sbjct: 1734 NLREDCVCKVGTILHRPHSAQCIPEKECAC 1763



 Score = 65.5 bits (158), Expect = 7e-10
 Identities = 92/363 (25%), Positives = 135/363 (37%), Gaps = 64/363 (17%)

Query: 73   PERDSICRA--WGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSP 130
            PE +  CR     +  + TFDG    L    SY LV      G+   I V +  +C  + 
Sbjct: 1433 PEWECPCRCSMLSELSIITFDGNNAALYSMASYILV---RIPGE---IIVAHIEKCSMNQ 1486

Query: 131  YTCSRAVSLFFVG---EQEIH------LAKEVTHGGMRVQLPHVMGSARLQQLAGYVIVR 181
                R   L F        IH      LA++V    + V LP       ++      ++ 
Sbjct: 1487 APSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQELSIEDSGSMYVIT 1546

Query: 182  HQSAFTLAWD---GASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKL---TDDVV 235
              +   + W    G   ++      L  +T GLCG  N DP DDL   +G +    +D+ 
Sbjct: 1547 TPAGLIIKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIG 1606

Query: 236  EFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALL-RPPFDACHAYVSP 294
             F+ SW+ +   +     T   P   C + +         QC  LL R  F  CH  VSP
Sbjct: 1607 LFIESWEIEKSFE----VTMRRPVRNCTEHD-------CSQCIDLLNRRIFIPCHDKVSP 1655

Query: 295  LPFTASCTSDLCQSMGDVATW-----CRALAEYARACAQAGRPLQGWRTQLRQCTVHCKE 349
                     D C+ M    T+     C AL+ Y   C +    +Q WRT    C++ C E
Sbjct: 1656 --------EDFCEKMWINYTYFWNYECDALSAYVALCNKFDICIQ-WRTP-DYCSLSCPE 1705

Query: 350  KAFTYNECIACCPA-SC-----HPRASCVDSEIACVDGCYCPNGLIF---EDGGCVAPAE 400
                Y  C+  C A +C     +   SC++      + C C  G I        C+   E
Sbjct: 1706 -GKEYQPCVRPCEARTCLNQWFYGHTSCLNLR----EDCVCKVGTILHRPHSAQCIPEKE 1760

Query: 401  CPC 403
            C C
Sbjct: 1761 CAC 1763



 Score = 62.8 bits (151), Expect = 5e-09
 Identities = 83/394 (21%), Positives = 137/394 (34%), Gaps = 62/394 (15%)

Query: 2007 PQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLS--------------FVTFDG 2052
            P G+ P  C       + G   C        RC I P++               F TFDG
Sbjct: 18   PSGSCPYECLNGAFCSKTGTCDCQIFQALGTRCQIIPNMGNGRDGICKTWGQYHFETFDG 77

Query: 2053 SHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNW---PPFCLVMLNMTH------L 2103
             +        YI ++           DC      +  W    P CL  +   +       
Sbjct: 78   IYYYFPGNCSYIFAK-----------DCGDLEPRYTVWVHNSPKCLGSVYSCYRSISLFF 126

Query: 2104 AHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVE 2163
            ++Q  I  +  ++  +   +  P +     IE      ++ T     + W   SG+ + +
Sbjct: 127  SNQEEIRIYGHEIKKNGISLTLPQTIGQIFIEKLADYILVKTTFGFSLAWDGISGIYL-K 185

Query: 2164 ASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSW--QVPSSLTSVGQTR 2221
             S+  K +  GLCG  +   ++D  +         ED A F +SW  Q P     V    
Sbjct: 186  LSEDHKGKSCGLCGNYNDIQSDDFIILQEDYT---EDIAMFANSWSVQTPDDTKCVLTPS 242

Query: 2222 FRPDSCATTDCSPCLRMVSNRT-------FSACHRFVPPESFCELWIRD---TKYVQQPC 2271
              P+ C++    P    +  +        F +CH ++ P  +    + D   T   +  C
Sbjct: 243  DFPNPCSSG--MPAFEAIFFKCQILLQFPFLSCHEYIDPYLYIASCVNDLCKTDDDETYC 300

Query: 2272 VALTVYVAMCHKFHVCIEWRRSDY--CPFLCSSDSTYQACVTACEPPKTCQDGILGPLDP 2329
             A T Y   C      I+  R D+  C   C     ++ C++ C P  T +   LG    
Sbjct: 301  RAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTCTFEKQCLG--SN 358

Query: 2330 EHCQVLGEGCVCSEGTILHRRHSALCIPEAKCAC 2363
             HC    +GC C +G ++    +  CI    C C
Sbjct: 359  LHCL---DGCYCPDGLVM---DNGTCISLENCPC 386



 Score = 44.3 bits (103), Expect = 0.002
 Identities = 58/283 (20%), Positives = 104/283 (36%), Gaps = 27/283 (9%)

Query: 2030 CPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLN 2089
            C  + C   C+I+ D  + +FDG       +    L +S D+     +   K      + 
Sbjct: 844  CTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLIKSADDSDISVIAQNKKCFDNDIV 903

Query: 2090 WPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPS-D 2148
                 L+ +  T +    T   + +K     Q  +   ++  +++   G+  ++  P  D
Sbjct: 904  CSKSVLISVGDTEIYLNDT--PYKQK-----QSGFFLENKSTYQLWKAGYYIVVYFPEKD 956

Query: 2149 IQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSW 2208
            I I W   + + I +     K +  GLCG  D   +ND+T  +   V  A     F DSW
Sbjct: 957  ITILWDRKTTIHI-KVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNAR---VFGDSW 1012

Query: 2209 -----QVPSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRD 2263
                 + P       +        A  +CS    ++ +  F++C   +   SF +    D
Sbjct: 1013 ALGQCESPDETIKPCEAHQNKFPYAKKECS----ILYSDIFASCRNVIDVTSFAKNCHED 1068

Query: 2264 T------KYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFLC 2300
            T         +  C ++  Y   C +  + I WR S  C   C
Sbjct: 1069 TCNCNLGGDCECLCTSIAAYAYKCCQEGISIHWRSSTVCSLDC 1111



 Score = 43.1 bits (100), Expect = 0.004
 Identities = 100/480 (20%), Positives = 164/480 (34%), Gaps = 79/480 (16%)

Query: 713  YSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCA--CPPDTYLDTQADLCVPRNQ 770
            Y PC  PC +TC D   PEA              VEGC   CP +  LD     CV    
Sbjct: 1281 YEPCATPCFKTCSD---PEALACKFLPP------VEGCLPYCPKNMILDEVTLKCVYPRD 1331

Query: 771  CS--CHFQGVDYPPGDSDIP--SLGHCHCKDGVMSCDSRAPAAACPAG-QVFVNCSDLHT 825
            C      +    PP    +P  ++        +   D   P        Q F    D   
Sbjct: 1332 CIPVIPTEPTLMPPAKPTVPMFTVWEMITPSDITVFDMLTPTTGLECEPQKFDPVYDCSQ 1391

Query: 826  DLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPG 885
             + L+ E     QL N S++          CP+ +          E   C ++G+     
Sbjct: 1392 YICLNME----WQLYNWSLN----------CPKDV----------EMPDCGFRGRPVQVN 1427

Query: 886  DQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD 945
              +  P   C C+              C+   +    TFDG            LV+   +
Sbjct: 1428 SDICCPEWECPCR--------------CSMLSELSIITFDGNNAALYSMASYILVRIPGE 1473

Query: 946  VSFSVIVE-NVNCYSSGMI---CRKFISINVGNSLIVFDDDSGNPSPESFLD----DKQE 997
            +  + I + ++N   SG I   C K +++      I+ +  +     +S +       QE
Sbjct: 1474 IIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQE 1533

Query: 998  VHTWRVGFFTLVHFPQEHITLLWDQRT---TVHVQAGPQWQGQLAGLCGNFDLKTINEMR 1054
            +     G   ++  P   I + W   T    +H            GLCG  +    +++R
Sbjct: 1534 LSIEDSGSMYVITTPAGLI-IKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLR 1592

Query: 1055 TPENLELTNPQEFGSSWAAVECPDTLDPRDMCVLNPLREPFAKKECS----ILLSEVFEI 1110
                  +TN ++ G    + E   + +   + +  P+R    + +CS    +L   +F  
Sbjct: 1593 MQNGTIITNMEDIGLFIESWEIEKSFE---VTMRRPVRN-CTEHDCSQCIDLLNRRIFIP 1648

Query: 1111 CHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDC 1170
            CH  V    F   C       +   + EC   ++SAY   C +  + + WRTP  C   C
Sbjct: 1649 CHDKVSPEDF---CEKMWINYTYFWNYEC--DALSAYVALCNKFDICIQWRTPDYCSLSC 1703


>gi|89191868 von Willebrand factor preproprotein [Homo sapiens]
          Length = 2813

 Score =  654 bits (1688), Expect = 0.0
 Identities = 393/1135 (34%), Positives = 560/1135 (49%), Gaps = 80/1135 (7%)

Query: 79   CRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVS 138
            C  +G   V TFDG  Y  +G  SY L G  +    S      N  +   S Y     + 
Sbjct: 35   CSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRSFSIIGDFQNGKRVSLSVY-----LG 89

Query: 139  LFFVGEQEIHLAKE--VTHGGMRVQLPHVMGSARLQQLAGYVIVRHQS-AFTLAWDGASA 195
             FF    +IHL     VT G  RV +P+      L+  AGY  +  ++  F    DG+  
Sbjct: 90   EFF----DIHLFVNGTVTQGDQRVSMPYASKGLYLETEAGYYKLSGEAYGFVARIDGSGN 145

Query: 196  VYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTS 255
              + +S      T GLCGN N   +DD +T  G LT D  +F +SW   +  Q      +
Sbjct: 146  FQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQ--WCERA 203

Query: 256  SLPRPPCLQQNPGTMQGVYEQCEALLRPP-FDACHAYVSPLPFTASCTSDLCQSMGDVAT 314
            S P   C   +    +G++EQC+ L     F  CH  V P PF A C   LC+  G +  
Sbjct: 204  SPPSSSCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVDPEPFVALCEKTLCECAGGLEC 263

Query: 315  WCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASC---HPRASC 371
             C AL EYAR CAQ G  L GW T    C+  C      Y +C++ C  +C   H    C
Sbjct: 264  ACPALLEYARTCAQEGMVLYGW-TDHSACSPVCPA-GMEYRQCVSPCARTCQSLHINEMC 321

Query: 372  VDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWE 431
             +    CVDGC CP G + ++G CV   ECPC   G  YPPG+ +  DCNTC C + +W 
Sbjct: 322  QER---CVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYPPGTSLSRDCNTCICRNSQWI 378

Query: 432  CSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDG 491
            CS   CP EC VTG  HF +FD R +TF   CQY+LA+     +F++ ++   C  ++D 
Sbjct: 379  CSNEECPGECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQDHSFSIVIETVQCADDRDA 438

Query: 492  ACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVG 551
             C +SV+V L       V L     V +  Q   +P    D   +R   +V   VR + G
Sbjct: 439  VCTRSVTVRLPGLHNSLVKLKHGAGVAMDGQDVQLPLLKGD---LRIQHTVTASVRLSYG 495

Query: 552  VRVLYDREGL-RLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKT 610
              +  D +G  RL +++   +   T GLCG +NGN  DDFL+P G+ E   + FGN+WK 
Sbjct: 496  EDLQMDWDGRGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKL 555

Query: 611  LSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACR 670
               C  L      DPC ++ +   +S +AC+VLT   F  C   +SP+PY   CR D C 
Sbjct: 556  HGDCQDL-QKQHSDPCALNPRMTRFSEEACAVLTSPTFEACHRAVSPLPYLRNCRYDVCS 614

Query: 671  C--GQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLA 728
            C  G+ CLC  LA YA  C   G+ V +R     C L+C   + Y  C  PC  TC+ L+
Sbjct: 615  CSDGRECLCGALASYAAACAGRGVRVAWR-EPGRCELNCPKGQVYLQCGTPCNLTCRSLS 673

Query: 729  SPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIP 788
             P        D+   + C+EGC CPP  Y+D + D CVP+ QC C++ G  + P D    
Sbjct: 674  YP--------DEECNEACLEGCFCPPGLYMDERGD-CVPKAQCPCYYDGEIFQPEDIFSD 724

Query: 789  SLGHCHCKDGVMSCD-SRAPAA-------------------ACPAGQVFVNCSDLHTDLE 828
                C+C+DG M C  S  P +                   +C    V + C   +   E
Sbjct: 725  HHTMCYCEDGFMHCTMSGVPGSLLPDAVLSSPLSHRSKRSLSCRPPMVKLVCPADNLRAE 784

Query: 829  -LSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQ 887
             L   +TC  Q  +L   + G C+SGC CP G++RH + C   E CPC  +GKEY PG+ 
Sbjct: 785  GLECTKTC--QNYDLECMSMG-CVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGET 841

Query: 888  VMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVK---STS 944
            V   C+TCVC+   + CT H C +TC+  G  HY TFDGL + F G C+  LV+    ++
Sbjct: 842  VKIGCNTCVCRDRKWNCTDHVCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSN 901

Query: 945  DVSFSVIVENVNCYSSGMICRKFISINV-GNSLIVFDDDSGNPSPESFLDDKQEVHTWRV 1003
              +F ++V N  C    + C+K ++I V G  + +FD +     P   + D+        
Sbjct: 902  PGTFRILVGNKGCSHPSVKCKKRVTILVEGGEIELFDGEVNVKRP---MKDETHFEVVES 958

Query: 1004 GFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLEL-T 1062
            G + ++   +  ++++WD+  ++ V     +Q ++ GLCGNFD    N++ T  NL++  
Sbjct: 959  GRYIILLLGKA-LSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDL-TSSNLQVEE 1016

Query: 1063 NPQEFGSSW-AAVECPDTLD-PRD----MCVLNPLREPFAKKECSILLSEVFEICHPVVD 1116
            +P +FG+SW  + +C DT   P D     C  N +++      C IL S+VF+ C+ +VD
Sbjct: 1017 DPVDFGNSWKVSSQCADTRKVPLDSSPATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVD 1076

Query: 1117 VTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCD 1171
               +   C+ DTC C   GDC CFC +++AYAH C QHG  V WRT  LCP  C+
Sbjct: 1077 PEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVVTWRTATLCPQSCE 1131



 Score =  240 bits (612), Expect = 2e-62
 Identities = 232/952 (24%), Positives = 362/952 (38%), Gaps = 148/952 (15%)

Query: 1994 EGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGS 2053
            +GQ +  +   +C +G  P  C      V+V  + C   W C C C+       VTFDG 
Sbjct: 1907 DGQTLLKSHRVNCDRGLRPS-CPNSQSPVKVE-ETCGCRWTCPCVCTGSSTRHIVTFDGQ 1964

Query: 2054 HVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFN 2113
            +  L     Y+L Q+ ++ L V +L   + + G       C+  + + H A  V +   +
Sbjct: 1965 NFKLTGSCSYVLFQNKEQDLEV-ILHNGACSPGARQG---CMKSIEVKHSALSVELHS-D 2019

Query: 2114 RKVTVDLQPVWPP-------VSRYG-----FRIEDTGHMYMILTPSDIQIQWLHSSGLMI 2161
             +VTV+ + V  P       V+ YG      R    GH++   TP + + Q        +
Sbjct: 2020 MEVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLGHIFTF-TPQNNEFQ--------L 2070

Query: 2162 VEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT- 2220
              + KT  ++ +GLCGICD + AND  L+DG+V     D    +  W V       GQT 
Sbjct: 2071 QLSPKTFASKTYGLCGICDENGANDFMLRDGTVT---TDWKTLVQEWTVQRP----GQTC 2123

Query: 2221 -RFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVA 2279
                 + C   D S C +++    F+ CH+ + P +F  +  +D+ + +Q C  +  Y  
Sbjct: 2124 QPILEEQCLVPDSSHC-QVLLLPLFAECHKVLAPATFYAICQQDSCHQEQVCEVIASYAH 2182

Query: 2280 MCHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGC 2339
            +C    VC++WR  D+C   C     Y  C   C  P+ C   +    D        EGC
Sbjct: 2183 LCRTNGVCVDWRTPDFCAMSCPPSLVYNHCEHGC--PRHCDGNVSSCGDHP-----SEGC 2235

Query: 2340 VCSEGTILHRRHSALCIPEAKCA-CTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPV 2398
             C    ++       C+PE  C  C    GV     E W      C    C +   +   
Sbjct: 2236 FCPPDKVMLE---GSCVPEEACTQCIGEDGVQHQFLEAWVPDHQPCQICTCLSGRKVNCT 2292

Query: 2399 DLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCE-GLAPTCRPGHRLLTHFQ 2457
               CP+ +  +C    EVA L    D CC    CVC+   C+    P C  G +  T   
Sbjct: 2293 TQPCPTAKAPTC-GLCEVARLRQNADQCCPEYECVCDPVSCDLPPVPHCERGLQP-TLTN 2350

Query: 2458 EDSCCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQE 2517
               C P+++C C  + C+    PSC   ++    +    CC  Y CAC +C +S   C  
Sbjct: 2351 PGECRPNFTCACRKEECKRVSPPSCPPHRLPTLRKT--QCCDEYECAC-NCVNSTVSCPL 2407

Query: 2518 G-------------------EALTVHRNTTELCCPLYQ-----CVCENF----------R 2543
            G                   + + VHR+T       ++     C C +           +
Sbjct: 2408 GYLASTATNDCGCTTTTCLPDKVCVHRSTIYPVGQFWEEGCDVCTCTDMEDAVMGLRVAQ 2467

Query: 2544 CPQVQC------GLGTALVEVWSPDRCCPYKSCECDCDT-----------------IPVP 2580
            C Q  C      G    L E     RC P  +CE    +                  P  
Sbjct: 2468 CSQKPCEDSCRSGFTYVLHEGECCGRCLP-SACEVVTGSPRGDSQSSWKSVGSQWASPEN 2526

Query: 2581 RCHLWEKSQLDEE---------------------FMHSVENVCGCAKYECVKAPVCLSRE 2619
             C + E  ++ EE                     F  S +    C    C +   C+   
Sbjct: 2527 PCLINECVRVKEEVFIQQRNVSCPQLEVPVCPSGFQLSCKTSACCPSCRCERMEACMLNG 2586

Query: 2620 LGVMQPGQTVVELSADGVCHTSRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDL 2679
              V+ PG+TV+      VC T RC   +  ++ F ++      C+  C     Y+   + 
Sbjct: 2587 T-VIGPGKTVMI----DVCTTCRCMVQVGVISGF-KLECRKTTCN-PCPLG--YKEENNT 2637

Query: 2680 AACCGSCRNVSCLFTFPNGTTSLFLPGASWIADCARHHCSSTPLGAVLVRSPIS-CPPLN 2738
              CCG C   +C      G         +    C  H C     G       ++ CPP +
Sbjct: 2638 GECCGRCLPTACTIQLRGGQIMTLKRDETLQDGCDTHFCKVNERGEYFWEKRVTGCPPFD 2697

Query: 2739 ETECAKVGGSVVPSLEGCCRTCKEDGRSCKKVTIRMT-IRKNECRSSTPVNLVSCDGRCP 2797
            E +C   GG ++     CC TC+E    C  +T R+  ++   C+S   V++  C G+C 
Sbjct: 2698 EHKCLAEGGKIMKIPGTCCDTCEEP--ECNDITARLQYVKVGSCKSEVEVDIHYCQGKCA 2755

Query: 2798 SASIYNYNINTYARFCKCCREVGLQRRSVQLFCATNATWVPYTVQEPTDCAC 2849
            S ++Y+ +IN     C CC     +   V L C TN + V + V    +C C
Sbjct: 2756 SKAMYSIDINDVQDQCSCCSPTRTEPMQVALHC-TNGSVVYHEVLNAMECKC 2806



 Score =  233 bits (594), Expect = 2e-60
 Identities = 150/461 (32%), Positives = 207/461 (44%), Gaps = 58/461 (12%)

Query: 376  IACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTA 435
            + CV GC CP G++  +  CVA   CPC   G  Y PG  VK  CNTC C   KW C+  
Sbjct: 802  MGCVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGETVKIGCNTCVCRDRKWNCTDH 861

Query: 436  VCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKS---RSSGTFTVTLQNAPCGLNQDGA 492
            VC A CS  G  H+ TFDG +Y FP  CQY+L +     + GTF + + N  C  +    
Sbjct: 862  VCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRILVGNKGCS-HPSVK 920

Query: 493  CVQSVSVILHQDPRRQVTLTQAGDVLLFD-QYKIIPPYTDDA-FEIRRLSSVFLRVRTNV 550
            C + V++           L + G++ LFD +  +  P  D+  FE+   S  ++ +    
Sbjct: 921  CKKRVTI-----------LVEGGEIELFDGEVNVKRPMKDETHFEVVE-SGRYIILLLGK 968

Query: 551  GVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKT 610
             + V++DR  L + + + Q + E   GLCG F+G   +D  S     E  P  FGNSWK 
Sbjct: 969  ALSVVWDRH-LSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKV 1027

Query: 611  LSACSPLVSGSPLDP----CDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRR 666
             S C+      PLD     C  ++   +    +C +LT ++F  C+  + P PY + C  
Sbjct: 1028 SSQCAD-TRKVPLDSSPATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVDPEPYLDVCIY 1086

Query: 667  DACRCGQ----PCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASK----------E 712
            D C C       C C T+A YAH+C +HG  V +R     C  SCE              
Sbjct: 1087 DTCSCESIGDCACFCDTIAAYAHVCAQHGKVVTWRTAT-LCPQSCEERNLRENGYECEWR 1145

Query: 713  YSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCA--CPPDTYLDTQADLCVPRNQ 770
            Y+ C   C  TCQ    P AC V         +CVEGC   CPP   LD     CV    
Sbjct: 1146 YNSCAPACQVTCQH-PEPLACPV---------QCVEGCHAHCPPGKILDELLQTCVDPED 1195

Query: 771  CS-CHFQGVDYPPG------DSDIPSLGHCHCKDGVMSCDS 804
            C  C   G  +  G       SD      CHC    ++C++
Sbjct: 1196 CPVCEVAGRRFASGKKVTLNPSDPEHCQICHCDVVNLTCEA 1236



 Score =  157 bits (396), Expect = 2e-37
 Identities = 110/380 (28%), Positives = 157/380 (41%), Gaps = 31/380 (8%)

Query: 439 AECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVS 498
           A CS+ G     TFDG  Y+F   C Y+LA      +F++       G  Q+G   + VS
Sbjct: 33  ARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRSFSI------IGDFQNG---KRVS 83

Query: 499 VILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDR 558
           + ++      + L   G V   DQ ++  PY      +   +  +       G     D 
Sbjct: 84  LSVYLGEFFDIHLFVNGTVTQGDQ-RVSMPYASKGLYLETEAGYYKLSGEAYGFVARIDG 142

Query: 559 EGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA---CS 615
            G    + +  R+   T GLCG FN   +DDF++  G   S P  F NSW   S    C 
Sbjct: 143 SG-NFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQWCE 201

Query: 616 PLVSGSPLDPCDVHLQAASYSV-QACSVL-TGEMFAPCSAFLSPVPYFEQCRRDACRC-- 671
              +  P   C++        + + C +L +  +FA C   + P P+   C +  C C  
Sbjct: 202 R--ASPPSSSCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVDPEPFVALCEKTLCECAG 259

Query: 672 GQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPE 731
           G  C C  L  YA  C + G+ +       AC+  C A  EY  CV+PC RTCQ L   E
Sbjct: 260 GLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQSLHINE 319

Query: 732 ACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLG 791
            C         ++ CV+GC+CP    LD    LCV   +C C   G  YPPG S      
Sbjct: 320 MC---------QERCVDGCSCPEGQLLD--EGLCVESTECPCVHSGKRYPPGTSLSRDCN 368

Query: 792 HCHCKDGVMSCDSRAPAAAC 811
            C C++    C +      C
Sbjct: 369 TCICRNSQWICSNEECPGEC 388



 Score =  136 bits (342), Expect = 3e-31
 Identities = 124/453 (27%), Positives = 180/453 (39%), Gaps = 72/453 (15%)

Query: 29   HRAKCAPSYLFSCFNGGECVHPA----------FCDCRRFNATGPRCQMVYNAGPERDSI 78
            H  +C       CF+ G+   P            C  R++N T   C          D+ 
Sbjct: 817  HENRCVALERCPCFHQGKEYAPGETVKIGCNTCVCRDRKWNCTDHVC----------DAT 866

Query: 79   CRAWGQHHVETFDGLYYYLSGKGSYTLVGRH-EPEGQSFSIQVHNDPQCGSSPYTCSRAV 137
            C   G  H  TFDGL Y   G+  Y LV  +      +F I V N   C      C + V
Sbjct: 867  CSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRILVGN-KGCSHPSVKCKKRV 925

Query: 138  SLFFVGEQEIHLAKEVTHGGMRVQLP-------HVMGSARLQQLAGYVIVRHQSAFTLAW 190
            ++   G +      E+  G + V+ P        V+ S R      Y+I+    A ++ W
Sbjct: 926  TILVEGGE-----IELFDGEVNVKRPMKDETHFEVVESGR------YIILLLGKALSVVW 974

Query: 191  DGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ--EQAPNQ 248
            D   ++ + +         GLCGN +    +DL +S+ ++ +D V+F +SW+   Q  + 
Sbjct: 975  DRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKVSSQCADT 1034

Query: 249  PPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDL--C 306
               P  SS   P     N      V   C  L    F  C+  V P P+   C  D   C
Sbjct: 1035 RKVPLDSS---PATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVDPEPYLDVCIYDTCSC 1091

Query: 307  QSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEK---------AFTYNEC 357
            +S+GD A +C  +A YA  CAQ G+ +  WRT    C   C+E+          + YN C
Sbjct: 1092 ESIGDCACFCDTIAAYAHVCAQHGKVVT-WRT-ATLCPQSCEERNLRENGYECEWRYNSC 1149

Query: 358  IACCPASC-HPRASCVDSEIACVDGC--YCPNGLIFED--GGCVAPAECP-CEFHGTLYP 411
               C  +C HP    +   + CV+GC  +CP G I ++    CV P +CP CE  G  + 
Sbjct: 1150 APACQVTCQHPEP--LACPVQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCEVAGRRFA 1207

Query: 412  PGSVV------KEDCNTCTCTSGKWECSTAVCP 438
             G  V       E C  C C      C     P
Sbjct: 1208 SGKKVTLNPSDPEHCQICHCDVVNLTCEACQEP 1240



 Score =  129 bits (323), Expect = 5e-29
 Identities = 101/363 (27%), Positives = 151/363 (41%), Gaps = 58/363 (15%)

Query: 422  TCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQ 481
            TC C   +W      CP  C+ +   H  TFDG+ +    +C Y+L +++      V L 
Sbjct: 1939 TCGC---RW-----TCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQD-LEVILH 1989

Query: 482  NAPCGLNQDGACVQSV-------SVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAF 534
            N  C       C++S+       SV LH D    + +T  G +       +  PY     
Sbjct: 1990 NGACSPGARQGCMKSIEVKHSALSVELHSD----MEVTVNGRL-------VSVPYVGGNM 2038

Query: 535  EIRRLSSVFLRVRTN-VGVRVLYDREGLRLYLQVDQR-WVEDTVGLCGTFNGNTQDDFLS 592
            E+    ++   VR N +G    +  +     LQ+  + +   T GLCG  + N  +DF+ 
Sbjct: 2039 EVNVYGAIMHEVRFNHLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFML 2098

Query: 593  PVGVPESTPQLFGNSWKTL---SACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFA 649
              G   +  +     W        C P++    L P   H          C VL   +FA
Sbjct: 2099 RDGTVTTDWKTLVQEWTVQRPGQTCQPILEEQCLVPDSSH----------CQVLLLPLFA 2148

Query: 650  PCSAFLSPVPYFEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEA 709
             C   L+P  ++  C++D+C   Q  +C  +A YAHLCR +G+ VD+R     CA+SC  
Sbjct: 2149 ECHKVLAPATFYAICQQDSCH--QEQVCEVIASYAHLCRTNGVCVDWRTP-DFCAMSCPP 2205

Query: 710  SKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRN 769
            S  Y+ C   C R C    S  +CG         D   EGC CPPD  +      CVP  
Sbjct: 2206 SLVYNHCEHGCPRHCDGNVS--SCG---------DHPSEGCFCPPDKVM--LEGSCVPEE 2252

Query: 770  QCS 772
             C+
Sbjct: 2253 ACT 2255



 Score =  119 bits (298), Expect = 4e-26
 Identities = 103/380 (27%), Positives = 149/380 (39%), Gaps = 50/380 (13%)

Query: 78   ICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAV 137
            +C      H+ TFDG  + L+G  SY L    E   Q   + +HN      +   C +++
Sbjct: 1949 VCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKE---QDLEVILHNGACSPGARQGCMKSI 2005

Query: 138  SLFFVG-EQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFT------LAW 190
             +       E+H   EVT  G  V +P+V G+  +     Y  + H+  F          
Sbjct: 2006 EVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEVNV---YGAIMHEVRFNHLGHIFTFT 2062

Query: 191  DGASAVYIKMSPELLGW-THGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQP 249
               +   +++SP+     T+GLCG  + +  +D +   G +T D    V  W  Q P Q 
Sbjct: 2063 PQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQRPGQ- 2121

Query: 250  PGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSM 309
               T   +    CL  +          C+ LL P F  CH  ++P  F A C  D C   
Sbjct: 2122 ---TCQPILEEQCLVPDSS-------HCQVLLLPLFAECHKVLAPATFYAICQQDSCHQ- 2170

Query: 310  GDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPR- 368
                  C  +A YA  C   G  +  WRT    C + C   +  YN C   CP  C    
Sbjct: 2171 ---EQVCEVIASYAHLCRTNGVCVD-WRTP-DFCAMSC-PPSLVYNHCEHGCPRHCDGNV 2224

Query: 369  ASCVDSEIACVDGCYCPNGLIFEDGGCVAPAEC-PC--------EFHGTLYPPGSVVKED 419
            +SC D      +GC+CP   +  +G CV    C  C        +F     P      + 
Sbjct: 2225 SSCGDHP---SEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPD----HQP 2277

Query: 420  CNTCTCTSG-KWECSTAVCP 438
            C  CTC SG K  C+T  CP
Sbjct: 2278 CQICTCLSGRKVNCTTQPCP 2297



 Score = 91.3 bits (225), Expect = 1e-17
 Identities = 82/333 (24%), Positives = 119/333 (35%), Gaps = 41/333 (12%)

Query: 862  RHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG---SFQCTLHP---------- 908
            R GD   LP++C          P  Q +   H   C RG   S   +  P          
Sbjct: 1888 RPGDVWTLPDQCHTV----TCQPDGQTLLKSHRVNCDRGLRPSCPNSQSPVKVEETCGCR 1943

Query: 909  --CASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSSGMI-CR 965
              C   CT    RH  TFDG  F   G+C   L ++  +    VI+ N  C       C 
Sbjct: 1944 WTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQN-KEQDLEVILHNGACSPGARQGCM 2002

Query: 966  KFISINVGNSLIVFDDD-----SGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLW 1020
            K I +      +    D     +G      ++    EV+ +      +      HI    
Sbjct: 2003 KSIEVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLGHIFTFT 2062

Query: 1021 DQRTTVHVQAGPQ-WQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDT 1079
             Q     +Q  P+ +  +  GLCG  D    N+    +    T+ +     W       T
Sbjct: 2063 PQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQRPGQT 2122

Query: 1080 LDP--RDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDC 1137
              P   + C++           C +LL  +F  CH V+    FY+ C  D+C   Q    
Sbjct: 2123 CQPILEEQCLVPD------SSHCQVLLLPLFAECHKVLAPATFYAICQQDSCHQEQ---- 2172

Query: 1138 ECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDC 1170
               C  +++YAH C  +GV VDWRTP  C   C
Sbjct: 2173 --VCEVIASYAHLCRTNGVCVDWRTPDFCAMSC 2203



 Score = 82.8 bits (203), Expect = 4e-15
 Identities = 85/360 (23%), Positives = 139/360 (38%), Gaps = 55/360 (15%)

Query: 2030 CPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDE---MLTVHVLDCKSANLG 2086
            C   EC   C +     F +FD  +        Y+L++   +    + +  + C      
Sbjct: 379  CSNEECPGECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQDHSFSIVIETVQCADDR-- 436

Query: 2087 HLNWPPFCL--VMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMIL 2144
                   C   V + +  L + +   +    V +D Q V  P+ +   RI+ T    + L
Sbjct: 437  ----DAVCTRSVTVRLPGLHNSLVKLKHGAGVAMDGQDVQLPLLKGDLRIQHTVTASVRL 492

Query: 2145 T-PSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAP 2203
            +   D+Q+ W    G ++V+ S     +  GLCG  +G+  +D     G      ED   
Sbjct: 493  SYGEDLQMDW-DGRGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVED--- 548

Query: 2204 FLDSWQVPSSLTSVGQ------------TRFRPDSCATTDCSPCLRMVSNRTFSACHRFV 2251
            F ++W++      + +            TRF  ++CA         ++++ TF ACHR V
Sbjct: 549  FGNAWKLHGDCQDLQKQHSDPCALNPRMTRFSEEACA---------VLTSPTFEACHRAV 599

Query: 2252 PPESFCELWIRDTKYV--------QQPCVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSD 2303
             P  +    +R+ +Y         +  C AL  Y A C    V + WR    C   C   
Sbjct: 600  SPLPY----LRNCRYDVCSCSDGRECLCGALASYAAACAGRGVRVAWREPGRCELNCPKG 655

Query: 2304 STYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCAC 2363
              Y  C T C    TC+   L   D E  +   EGC C  G  +  R    C+P+A+C C
Sbjct: 656  QVYLQCGTPCN--LTCRS--LSYPDEECNEACLEGCFCPPGLYMDERGD--CVPKAQCPC 709



 Score = 79.7 bits (195), Expect = 4e-14
 Identities = 108/447 (24%), Positives = 164/447 (36%), Gaps = 67/447 (14%)

Query: 1986 DCVRHICLEGQLIRVNQSQHCPQGAAPPRCGIL--------GLAVRVGGDRC-------- 2029
            +C+   C+ G L      +H  +  A  RC           G  V++G + C        
Sbjct: 798  ECMSMGCVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGETVKIGCNTCVCRDRKWN 857

Query: 2030 CPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS--PDEMLTVHVLDCKSANLGH 2087
            C    C   CS      ++TFDG       E  Y+L Q        T  +L     N G 
Sbjct: 858  CTDHVCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRIL---VGNKGC 914

Query: 2088 LNWPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPS 2147
             +  P       +T L     I+ F+ +V V      P      F + ++G   ++L   
Sbjct: 915  SH--PSVKCKKRVTILVEGGEIELFDGEVNVKR----PMKDETHFEVVESGRYIILLLGK 968

Query: 2148 DIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDS 2207
             + + W     + +V   +T + +  GLCG  DG   NDLT  +  V    EDP  F +S
Sbjct: 969  ALSVVWDRHLSISVV-LKQTYQEKVCGLCGNFDGIQNNDLTSSNLQV---EEDPVDFGNS 1024

Query: 2208 WQVPSSLTSVGQTRF--RPDSCAT-----TDCSPCLRMVSNRTFSACHRFVPPESFCELW 2260
            W+V S      +      P +C       T      R++++  F  C++ V PE + ++ 
Sbjct: 1025 WKVSSQCADTRKVPLDSSPATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVDPEPYLDVC 1084

Query: 2261 IRDTKYVQQP------CVALTVYVAMCHKFHVCIEWRRSDYCPFLCSS----------DS 2304
            I DT   +        C  +  Y  +C +    + WR +  CP  C            + 
Sbjct: 1085 IYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVVTWRTATLCPQSCEERNLRENGYECEW 1144

Query: 2305 TYQACVTACEPPKTCQDGILGPLDPEHCQV-LGEGC--VCSEGTILHRRHSALCIPEAKC 2361
             Y +C  AC+   TCQ       +P  C V   EGC   C  G IL       C+    C
Sbjct: 1145 RYNSCAPACQ--VTCQHP-----EPLACPVQCVEGCHAHCPPGKILDELLQT-CVDPEDC 1196

Query: 2362 ACTDSMGVPRALGE--TWNSSLSGCCQ 2386
               +  G   A G+  T N S    CQ
Sbjct: 1197 PVCEVAGRRFASGKKVTLNPSDPEHCQ 1223



 Score = 74.7 bits (182), Expect = 1e-12
 Identities = 89/366 (24%), Positives = 137/366 (37%), Gaps = 38/366 (10%)

Query: 2017 ILGLAVRVGGDRCCPLWE---CACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEML 2073
            +L LA+ + G  C           RCS+F      TFDGS  +      Y+L+    +  
Sbjct: 10   LLALALILPGTLCAEGTRGRSSTARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRS 69

Query: 2074 TVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRF-NRKVTVDLQPVWPPVSRYGF 2132
               + D ++     L+            +L     I  F N  VT   Q V  P +  G 
Sbjct: 70   FSIIGDFQNGKRVSLS-----------VYLGEFFDIHLFVNGTVTQGDQRVSMPYASKGL 118

Query: 2133 RIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDG 2192
             +E     Y +   +   +  +  SG   V  S     +  GLCG  +  A +D   ++G
Sbjct: 119  YLETEAGYYKLSGEAYGFVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEG 178

Query: 2193 SVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTD-------CSPCLRMVSNRTFS 2245
            ++     DP  F +SW + S      +      SC  +           C  + S   F+
Sbjct: 179  TLTS---DPYDFANSWALSSGEQWCERASPPSSSCNISSGEMQKGLWEQCQLLKSTSVFA 235

Query: 2246 ACHRFVPPESF---CELWIRD-TKYVQQPCVALTVYVAMC-HKFHVCIEWRRSDYCPFLC 2300
             CH  V PE F   CE  + +    ++  C AL  Y   C  +  V   W     C  +C
Sbjct: 236  RCHPLVDPEPFVALCEKTLCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVC 295

Query: 2301 SSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAK 2360
             +   Y+ CV+ C   +TCQ   +  +  E C    +GC C EG +L      LC+   +
Sbjct: 296  PAGMEYRQCVSPC--ARTCQSLHINEMCQERCV---DGCSCPEGQLL---DEGLCVESTE 347

Query: 2361 CACTDS 2366
            C C  S
Sbjct: 348  CPCVHS 353



 Score = 62.4 bits (150), Expect = 6e-09
 Identities = 28/56 (50%), Positives = 35/56 (62%), Gaps = 1/56 (1%)

Query: 1336 CEWRYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCPTPQVLDEVTQRCVYLEDC 1391
            CEWRY++CA  C  TC+ P   +C  V  VEGC   CP  ++LDE+ Q CV  EDC
Sbjct: 1142 CEWRYNSCAPACQVTCQHPEPLAC-PVQCVEGCHAHCPPGKILDELLQTCVDPEDC 1196



 Score = 45.4 bits (106), Expect = 8e-04
 Identities = 53/200 (26%), Positives = 73/200 (36%), Gaps = 50/200 (25%)

Query: 331  RPLQGWRTQLRQC----TVHCKEKAFTYNECIACCPASCHP-------RASCVDSEIACV 379
            R LQ   T   +C    T  C+++     EC    P SC P       +  C D E  C 
Sbjct: 2342 RGLQPTLTNPGECRPNFTCACRKE-----ECKRVSPPSCPPHRLPTLRKTQCCD-EYECA 2395

Query: 380  DGCY-----CPNGLIFE----DGGCVAPAECP---CEFHGTLYPPGSVVKEDCNTCTCTS 427
              C      CP G +      D GC      P   C    T+YP G   +E C+ CTCT 
Sbjct: 2396 CNCVNSTVSCPLGYLASTATNDCGCTTTTCLPDKVCVHRSTIYPVGQFWEEGCDVCTCTD 2455

Query: 428  GK--------WECSTAVCPAEC--SVTGDIHFTTFDGRRYTFPATCQYILAKSR------ 471
             +         +CS   C   C    T  +H     GR    P+ C+ +    R      
Sbjct: 2456 MEDAVMGLRVAQCSQKPCEDSCRSGFTYVLHEGECCGR--CLPSACEVVTGSPRGDSQSS 2513

Query: 472  --SSGTFTVTLQNAPCGLNQ 489
              S G+   + +N PC +N+
Sbjct: 2514 WKSVGSQWASPEN-PCLINE 2532



 Score = 34.7 bits (78), Expect = 1.4
 Identities = 22/63 (34%), Positives = 28/63 (44%), Gaps = 6/63 (9%)

Query: 1331 AAYPICE--WRYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCPTPQVLDEVTQRCVYL 1388
            A  P+C     Y  C SPC +TC+            V+GC   CP  Q+LDE    CV  
Sbjct: 290  ACSPVCPAGMEYRQCVSPCARTCQSLHINEMCQERCVDGC--SCPEGQLLDE--GLCVES 345

Query: 1389 EDC 1391
             +C
Sbjct: 346  TEC 348


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score =  615 bits (1585), Expect = e-175
 Identities = 362/1124 (32%), Positives = 557/1124 (49%), Gaps = 59/1124 (5%)

Query: 77   SICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRA 136
            ++C  WG  H +TFDG  +   G   Y          + F++ +   P    +P      
Sbjct: 35   NVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQAEAPAGVESI 94

Query: 137  VSLFFVGEQEIHLAKEVTH-GGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASA 195
              L  + +  I+L + +    G  V  PH      +++   Y  V  ++  TL W+   A
Sbjct: 95   --LLTIKDDTIYLTRHLAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLTLMWNREDA 152

Query: 196  VYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTS 255
            + +++  +    T GLCG+ N         S G L   + EF +    Q  NQP      
Sbjct: 153  LMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPL-EFGNM---QKINQP-----D 203

Query: 256  SLPRPPCLQQNPGTMQGVYEQCEALLRPP-FDACHAYVSPLPFTASCTSDLCQSMGDVAT 314
             +   P  +  P +      +CE LL    F  C   V   P+  +C  D C+  G    
Sbjct: 204  VVCEDPEEEVAPASCSEHRAECERLLTAEAFADCQDLVPLEPYLRACQQDRCRCPGGDTC 263

Query: 315  WCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDS 374
             C  +AE++R C+ AG     WRT    C   C            C     H   S +  
Sbjct: 264  VCSTVAEFSRQCSHAGGRPGNWRTATL-CPKTCPGNLVYLESGSPCMDTCSHLEVSSLCE 322

Query: 375  EIACVDGCYCPNGLIFED---GGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWE 431
            E   +DGC+CP G +++D    GCV  ++C C  HG LY PG  +  DC  C C +G+W 
Sbjct: 323  EHR-MDGCFCPEGTVYDDIGDSGCVPVSQCHCRLHGHLYTPGQEITNDCEQCVCNAGRWV 381

Query: 432  CSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDG 491
            C    CP  C++ G  H TTFDG+ YTF   C Y+LAK   + ++ +  + APCG     
Sbjct: 382  CKDLPCPGTCALEGGSHITTFDGKTYTFHGDCYYVLAKGDHNDSYALLGELAPCGSTDKQ 441

Query: 492  ACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVG 551
             C+++V  +L  D ++ V + ++   +L ++ ++  P+   +F + R SS  + V   +G
Sbjct: 442  TCLKTV--VLLADKKKNVVVFKSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVSMAIG 499

Query: 552  VRVLYDREG-LRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKT 610
            VR+       ++L++ +DQ       GLCG FNG   DDF +  G+ E+T   F N+WK 
Sbjct: 500  VRLQVQLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKA 559

Query: 611  LSACSPLVSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDA 668
             S+C   +     DPC +++++A+Y+   CS+L  T   F  C + + P  Y+++C+ D 
Sbjct: 560  QSSCHDKLDWLD-DPCSLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDT 618

Query: 669  CRC--GQPCLCATLAHYAHLCRRHGLPVDFRARLPACAL---SCEASKEYSPCVAPCGRT 723
            C C   + CLCA L+ YA  C   G+ + +  R   C     SC  S+ +   +  C +T
Sbjct: 619  CNCQNNEDCLCAALSSYARACTAKGVML-WGWREHVCNKDVGSCPNSQVFLYNLTTCQQT 677

Query: 724  CQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPG 783
            C+ L+  ++  ++G         V+GC CP  T+LD +   CVP  +CSC+ +G+    G
Sbjct: 678  CRSLSEADSHCLEGFAP------VDGCGCPDHTFLDEKGR-CVPLAKCSCYHRGLYLEAG 730

Query: 784  DSDIPSLGHCHCKDGVMSCDS-RAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNL 842
            D  +     C C+DG + C   R    +C A ++ ++CS+L T L  S+ R    Q L  
Sbjct: 731  DVVVRQEERCVCRDGRLHCRQIRLIGQSCTAPKIHMDCSNL-TALATSKPRALSCQTLAA 789

Query: 843  SVSARGPCLSGCACPQGLLRHG-DACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGS 901
                   C+SGC CP GL+  G   C + +ECPC      Y  G ++   C+TC C+RG 
Sbjct: 790  GYY-HTECVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGR 848

Query: 902  FQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVK-----STSDVSFSVIVENVN 956
            + CT   C  TC+ YG  HY TFDG  +DF G C    V+     ++S  SFS+I ENV 
Sbjct: 849  WVCTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVP 908

Query: 957  CYSSGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVH-----TWRVGFFTLVHF 1011
            C ++G+ C K I I +G + +  +D          +  + E H     T  VG + +V  
Sbjct: 909  CGTTGVTCSKAIKIFMGRTELKLEDK------HRVVIQRDEGHHVAYTTREVGQYLVVE- 961

Query: 1012 PQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSW 1071
                I ++WD+RTTV ++  P ++G + GLCGNFD ++ N+  T +++ +++  +FG+SW
Sbjct: 962  SSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSW 1021

Query: 1072 A-AVECPDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCG 1130
              A  CPD     + C LNP R  +A+K+CSIL S VF ICH  VD   FY  C+ D+C 
Sbjct: 1022 KEAPTCPDVSTNPEPCSLNPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCS 1081

Query: 1131 CSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFN 1174
            C  GGDCECFC++V++YA +C + G  V WRTP LCP  CD++N
Sbjct: 1082 CDTGGDCECFCSAVASYAQECTKEGACVFWRTPDLCPIFCDYYN 1125



 Score =  250 bits (639), Expect = 1e-65
 Identities = 228/921 (24%), Positives = 364/921 (39%), Gaps = 187/921 (20%)

Query: 25   ERRLHRAKCAPSYLFSCFNGGECVHPAFCDCRRFN--------ATGPRCQMVYNAGP--- 73
            E R+    C    ++       CV  + C CR            T    Q V NAG    
Sbjct: 323  EHRMDGCFCPEGTVYDDIGDSGCVPVSQCHCRLHGHLYTPGQEITNDCEQCVCNAGRWVC 382

Query: 74   ---ERDSICRAWGQHHVETFDGLYYYLSGKGSYTLV-GRHEPEGQSFSIQVHNDPQCGSS 129
                    C   G  H+ TFDG  Y   G   Y L  G H     S+++     P CGS+
Sbjct: 383  KDLPCPGTCALEGGSHITTFDGKTYTFHGDCYYVLAKGDHN---DSYALLGELAP-CGST 438

Query: 130  P-YTCSRAVSLFFVGEQEIHLAKE---VTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSA 185
               TC + V L    ++ + + K    V    ++V LPHV  S  + + + Y I+   + 
Sbjct: 439  DKQTCLKTVVLLADKKKNVVVFKSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVSMAI 498

Query: 186  ---FTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ 242
                 +       +++ +     G   GLCGN N    DD  T+SG +      F ++W+
Sbjct: 499  GVRLQVQLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWK 558

Query: 243  EQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRP--PFDACHAYVSPLPF--- 297
             Q+               PC   N  +       C  L +   PF  CH+ V P  +   
Sbjct: 559  AQSSCHDKLDWLDD----PC-SLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKR 613

Query: 298  ----TASCTSD---LCQSMGD---------VATW-------------------------- 315
                T +C ++   LC ++           V  W                          
Sbjct: 614  CKYDTCNCQNNEDCLCAALSSYARACTAKGVMLWGWREHVCNKDVGSCPNSQVFLYNLTT 673

Query: 316  ----CRALAEYARACAQAGRPLQGW----------------------------------- 336
                CR+L+E    C +   P+ G                                    
Sbjct: 674  CQQTCRSLSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVV 733

Query: 337  -----RTQLRQCTVHCKEKAFTYNECIA----------CCPASCHPRASCVDSEIA---- 377
                 R   R   +HC++       C A             A+  PRA    +  A    
Sbjct: 734  VRQEERCVCRDGRLHCRQIRLIGQSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYH 793

Query: 378  --CVDGCYCPNGLIFED-GGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWECST 434
              CV GC CP+GL+ +  GGCV   ECPC  +  LY  G+ +K DCNTCTC  G+W C+ 
Sbjct: 794  TECVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQ 853

Query: 435  AVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAK-----SRSSGTFTVTLQNAPCGLNQ 489
            AVC   CS+ G  H+ TFDG+ Y F   C Y+  +     + S G+F++  +N PCG   
Sbjct: 854  AVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTT- 912

Query: 490  DGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDD---AFEIRRLSSVFLRV 546
               C +++ + + +            ++ L D+++++    +    A+  R +   +L V
Sbjct: 913  GVTCSKAIKIFMGRT-----------ELKLEDKHRVVIQRDEGHHVAYTTREVGQ-YLVV 960

Query: 547  RTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGN 606
             ++ G+ V++D+    +++++   +     GLCG F+  + +DF +   +  S+   FGN
Sbjct: 961  ESSTGIIVIWDKR-TTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGN 1019

Query: 607  SWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRR 666
            SWK    C P VS +P +PC ++    S++ + CS+L   +F+ C + + P P++E C  
Sbjct: 1020 SWKEAPTC-PDVSTNP-EPCSLNPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVH 1077

Query: 667  DACRCGQ----PCLCATLAHYAHLCRRHGLPVDFRARLPACALSC-------EASKEYSP 715
            D+C C       C C+ +A YA  C + G  V +R     C + C       E    Y P
Sbjct: 1078 DSCSCDTGGDCECFCSAVASYAQECTKEGACVFWRTP-DLCPIFCDYYNPPHECEWHYEP 1136

Query: 716  CVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGC--ACPPDTYL-DTQADLCVPRNQCS 772
            C      TC+ +      G+     +S    +EGC   CP D  + +     CV  ++C 
Sbjct: 1137 CGNRSFETCRTIN-----GIHSNISVSY---LEGCYPRCPKDRPIYEEDLKKCVTADKCG 1188

Query: 773  CHFQGVDYPPGDSDIPSLGHC 793
            C+ +   YPPG S +P+   C
Sbjct: 1189 CYVEDTHYPPGAS-VPTEETC 1208



 Score =  244 bits (624), Expect = 7e-64
 Identities = 315/1346 (23%), Positives = 473/1346 (35%), Gaps = 216/1346 (16%)

Query: 1415 PTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNP-PVTATEEPVVSPGPTQTTLQQPL 1473
            PTP+  +   +     T T  P  TP    T    P   T T  P  +P  TQT    P+
Sbjct: 3797 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3856

Query: 1474 ELTASQLPAGP---TESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRV 1530
              T +  P      T++P +  +T +    P TP     P   QTPT   +     TT  
Sbjct: 3857 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPT----PTGTQTPTTTPI-----TTTT 3906

Query: 1531 TVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGS---LPVRTTPL-----QPSLTASP 1582
            TV    +P  T +  + P      +T   T  G  +    P+ TT        P+ T +P
Sbjct: 3907 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3966

Query: 1583 SSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTA 1642
            ++ P+ +   ++ +PT +G+     TP  T   + T  P PT   + +  +TP+T   T 
Sbjct: 3967 TTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTV 4023

Query: 1643 AE-------QVPVS-PLATRSLEIVLSTEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQ 1693
                     Q P + P+ T +      T  G +   + P+ +  +  P P P+    P  
Sbjct: 4024 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 4083

Query: 1694 HTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVG 1753
             T + T +   P  TP      T T     TP  +  +  P+   +G    T+ P+    
Sbjct: 4084 -TPITTTTTVTPTPTP------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 4136

Query: 1754 TSAPVATPGPKASVITTPLQPQAT--------------TLPAQTLSPVLPFTPAAMTQAH 1799
            T  P  TP    +  TTP+    T              T P  T + V P      TQ  
Sbjct: 4137 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTG 4196

Query: 1800 PPTHIA-----------PPAAGTAPGLLLGATLP---TSGVLPVAEGTASMVSVVPRKST 1845
            PPTH +           PP   + P      + P   ++ +L        M S  P  + 
Sbjct: 4197 PPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTP 4256

Query: 1846 TGKVAILSKQ-VSLPTSMYGSAEGGPTE-LTPATSHPLTPLVAEPEGAQAGTALPVPTSY 1903
            T          +S P S   S  G PT   T  +S   TP   +     A T  P P S 
Sbjct: 4257 TAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLST 4316

Query: 1904 ALSRVSARTAPQDSMLVLLPQLAEAH---------GTSAGPHLAAEPVDEATTEPSGRSA 1954
                 +    P  S +++   L + +         GT              T E    S 
Sbjct: 4317 PSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSC 4376

Query: 1955 PALSIVEGLAEALATTTEANTSTTCVPIAEQ---------------------DCVRHICL 1993
            P+             T    +ST   P                         DC    C 
Sbjct: 4377 PSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECPDFDPPRQENETWWLCDCFMATCK 4436

Query: 1994 EGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGG-DRCCPLWECACRCSIFPDLSFVTFDG 2052
                + + + +  P     P C      VRV   D CC  WEC C C+ + D  +VTFDG
Sbjct: 4437 YNNTVEIVKVECEPPPM--PTCSNGLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDG 4494

Query: 2053 SHVALFKEAIYILSQ--SPDEMLTVHVLDCKSANLGHLNWPP----FCLVMLNMTHLAHQ 2106
             + +      Y+L +  SP        +D     + + +  P     C   L + H   +
Sbjct: 4495 LYYSYQGNCTYVLVEEISPS-------VDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQE 4547

Query: 2107 VTIDRFNR-----KVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMI 2161
            V I   +      +V V+ Q V  P  +YG  +  +G  Y++  P    +   +     +
Sbjct: 4548 VLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVLVSYNGLSFSV 4607

Query: 2162 VEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVP---------S 2212
                        G CG C    ++D  L  G +V   E  A   D W V          S
Sbjct: 4608 RLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAA---DQWLVNDPSKPHCPHS 4664

Query: 2213 SLTSVGQTRFRPDSCATT---DC--SPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYV 2267
            S T+       P    TT   DC  SP  +++ +  F+ CH  VPP+ + +  + D+ ++
Sbjct: 4665 SSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSCFM 4724

Query: 2268 ---QQPCVALTVYVAMCHKFHVCIEWRRSDY--CPFLCSSDSTYQACVTACEPPKTCQDG 2322
                  C +L  Y A+C + ++C++WR   +  C   C S   YQAC  A EP  TC+  
Sbjct: 4725 PGSSLECASLQAYAALCAQQNICLDWRNHTHGACLVECPSHREYQACGPAEEP--TCKSS 4782

Query: 2323 ILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLS 2382
                   ++  VL EGC C EGT+ +     +C+    C C     VPR  GE +     
Sbjct: 4783 S----SQQNNTVLVEGCFCPEGTMNYAPGFDVCVKT--CGCVGPDNVPREFGEHFEFDCK 4836

Query: 2383 GCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGE-VALLLPTKDPCCLGTVCVCNQTLCEG 2441
             C     +    I+     C       C+  G  +A  +   D CC  TVC CN +LC+ 
Sbjct: 4837 NCVC--LEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTCCNITVCKCNTSLCKE 4894

Query: 2442 LAPTCRPGHRLLTHFQEDSCCPSYSCECDPDLC---EAELVPSCRQDQILITGRLGDSCC 2498
                C  G  + +      CCP Y CE    +C    AE  P                  
Sbjct: 4895 KPSVCPLGFEVKSKMVPGRCCPFYWCE-SKGVCVHGNAEYQPG----------------S 4937

Query: 2499 TSYFCACGDCPDSIPECQEGEALTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEV 2558
              Y   C DC      C +     V  NT      L    C +  C    C  G  L+E 
Sbjct: 4938 PVYSSKCQDC-----VCTD----KVDNNTL-----LNVIACTHVPC-NTSCSPGFELME- 4981

Query: 2559 WSPDRCCPYKSCE---C---------------DCDTIPVPRCHLWEKSQLDEEFMHSVEN 2600
             +P  CC  K CE   C               D  + P   C  +   ++  + + SV N
Sbjct: 4982 -APGECC--KKCEQTHCIIKRPDNQHVILKPGDFKSDPKNNCTFFSCVKIHNQLISSVSN 5038

Query: 2601 VCGCAKYECVKAPVCLSRELGVMQPG 2626
            +  C  ++   A +C+   +  M  G
Sbjct: 5039 IT-CPNFD---ASICIPGSITFMPNG 5060



 Score =  157 bits (398), Expect = 1e-37
 Identities = 125/396 (31%), Positives = 180/396 (45%), Gaps = 40/396 (10%)

Query: 79   CRAWGQHHVETFDGLYYYLSGKGSYTLV----GRHEPEGQSFSIQVHNDPQCGSSPYTCS 134
            C  +G  H  TFDG YY   G  SY  V    G++   G SFSI   N P CG++  TCS
Sbjct: 860  CSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLG-SFSIITENVP-CGTTGVTCS 917

Query: 135  RAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGAS 194
            +A+ +F +G  E+ L  +      R +  HV  + R  ++  Y++V   +   + WD  +
Sbjct: 918  KAIKIF-MGRTELKLEDKHRVVIQRDEGHHVAYTTR--EVGQYLVVESSTGIIVIWDKRT 974

Query: 195  AVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTT 254
             V+IK++P   G   GLCGN +    +D  T    +    ++F +SW+E     P  P  
Sbjct: 975  TVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEA----PTCPDV 1030

Query: 255  SSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQ--SMGDV 312
            S+ P P  L  NP       +QC  L    F  CH+ V P PF  +C  D C   + GD 
Sbjct: 1031 STNPEPCSL--NPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDC 1088

Query: 313  ATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCK------EKAFTYNECIACCPASCH 366
              +C A+A YA+ C + G  +  WRT    C + C       E  + Y  C      +C 
Sbjct: 1089 ECFCSAVASYAQECTKEGACVF-WRTP-DLCPIFCDYYNPPHECEWHYEPCGNRSFETCR 1146

Query: 367  PRASCVDS-EIACVDGCY--CPNGL-IFEDG--GCVAPAECPCEFHGTLYPPGSVV--KE 418
                   +  ++ ++GCY  CP    I+E+    CV   +C C    T YPPG+ V  +E
Sbjct: 1147 TINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGASVPTEE 1206

Query: 419  DCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDG 454
             C +C CT+     S  VC  E    G I   T DG
Sbjct: 1207 TCKSCVCTNS----SQVVCRPE---EGKILNQTQDG 1235



 Score =  122 bits (305), Expect = 7e-27
 Identities = 140/630 (22%), Positives = 222/630 (35%), Gaps = 66/630 (10%)

Query: 1380 EVTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALT 1439
            E+  +C    +CV     + T    N T P +  + T +   P  +    +TPT     T
Sbjct: 1870 EINVQCC---ECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPT----TT 1922

Query: 1440 PAAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLA 1499
            P    TT     VT T  P  +  PT T +     +T +  P G T++P +  +T +   
Sbjct: 1923 PITTTTT-----VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-TQTPTTTPITTTTTV 1976

Query: 1500 IPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAV 1559
             P TP     P   QTPT   +     TT  TV    +P  T +  + P      +T   
Sbjct: 1977 TP-TP----TPTGTQTPTTTPI-----TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2026

Query: 1560 TVRG---HGSLPVRTTPL-----QPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAV 1611
            T  G     + P+ TT        P+ T +P++ P+ +   ++ +PT +G+     TP  
Sbjct: 2027 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2086

Query: 1612 TKVISRTGVPQPTQAQSASSPSTPLTVAGT-------AAEQVP-VSPLATRSLEIVLSTE 1663
            T   + T  P PT   + +  +TP+T   T          Q P  +P+ T +      T 
Sbjct: 2087 T---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2143

Query: 1664 KG-EAGHSQPMGSPASPQPHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLA 1722
             G +   + P+ +  +  P P P+    P   T + T +   P  TP      T T    
Sbjct: 2144 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTPTP------TGTQTPT 2196

Query: 1723 ATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLP-- 1780
             TP  +  +  P+   +G    T+ P+    T  P  TP    +  TTP+    T  P  
Sbjct: 2197 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2256

Query: 1781 ------AQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTA 1834
                    T +P+   T    T     T        T    +     PT    P      
Sbjct: 2257 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2316

Query: 1835 SMVSVVPRKSTTGKVAILSKQVSLPTSMYGSAEGGPTE---LTPATSHPLTPLVAEPEGA 1891
            +  +V P  + TG     +  ++  T++  +     T+    TP T+         P G 
Sbjct: 2317 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2376

Query: 1892 QAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLAEAHGTSAGPHLAAEPVDEATTEPSG 1951
            Q  T  P+ T+  ++     T  Q      +        T+  P          TT P  
Sbjct: 2377 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT-----TTVTPTPTPTGTQTPTTTPIT 2431

Query: 1952 RSAPALSIVEGLAEALATTTEANTSTTCVP 1981
             +               TTT   T+TT  P
Sbjct: 2432 TTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2461



 Score =  120 bits (302), Expect = 1e-26
 Identities = 139/590 (23%), Positives = 212/590 (35%), Gaps = 58/590 (9%)

Query: 1415 PTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNP-PVTATEEPVVSPGPTQTTLQQPL 1473
            PTP+  +   +     T T  P  TP    T    P   T T  P  +P  TQT    P+
Sbjct: 3705 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3764

Query: 1474 ELTASQLPAGP---TESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRV 1530
              T +  P      T++P +  +T +    P TP     P   QTPT   +     TT  
Sbjct: 3765 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPT----PTGTQTPTTTPI-----TTTT 3814

Query: 1531 TVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGS---LPVRTTPL-----QPSLTASP 1582
            TV    +P  T +  + P      +T   T  G  +    P+ TT        P+ T +P
Sbjct: 3815 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3874

Query: 1583 SSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTA 1642
            ++ P+ +   ++ +PT +G+     TP  T   + T  P PT   + +  +TP+T   T 
Sbjct: 3875 TTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTV 3931

Query: 1643 AE-------QVPVS-PLATRSLEIVLSTEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQ 1693
                     Q P + P+ T +      T  G +   + P+ +  +  P P P+    P  
Sbjct: 3932 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3991

Query: 1694 HTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVG 1753
             T + T +   P  TP      T T     TP  +  +  P+   +G    T+ P+    
Sbjct: 3992 -TPITTTTTVTPTPTP------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 4044

Query: 1754 TSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAP 1813
            T  P  TP    +  TTP+    T  P  T +     T   +T     T    P     P
Sbjct: 4045 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 4104

Query: 1814 GLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGSAEGGPTEL 1873
                  T  T    P   GT        +  TT  +   +     PT   G+     T +
Sbjct: 4105 TTTPITTTTTVTPTPTPTGT--------QTPTTTPITTTTTVTPTPTPT-GTQTPTTTPI 4155

Query: 1874 TPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDS--MLVLLPQLAEAHGT 1931
            T  T+   TP    P G Q  T  P+ T+  ++     T  Q           +AE   +
Sbjct: 4156 TTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTS 4212

Query: 1932 SAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 1981
            +  P  +      +T+ P   S   LS    L  A+  T+ A  ST   P
Sbjct: 4213 NPPPESSTPQTSRSTSSPLTESTTLLST---LPPAIEMTSTAPPSTPTAP 4259



 Score =  120 bits (300), Expect = 3e-26
 Identities = 141/643 (21%), Positives = 219/643 (34%), Gaps = 62/643 (9%)

Query: 1373 PTPQVLDEVTQRCVYLEDCVEPAVWVPTEA--LGNETLPPSQGLPTPSDEEPQLSQESPR 1430
            PTP     +T                PT        T+ P+   PTP+  +   +     
Sbjct: 1893 PTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITT 1949

Query: 1431 TPTHRPALTPAAPLTTALNP-PVTATEEPVVSPGPTQTTLQQPLELTASQLPAGP---TE 1486
            T T  P  TP    T    P   T T  P  +P  TQT    P+  T +  P      T+
Sbjct: 1950 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2009

Query: 1487 SPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRS 1546
            +P +  +T +    P TP     P   QTPT   +     TT  TV    +P  T +  +
Sbjct: 2010 TPTTTPITTTTTVTP-TPT----PTGTQTPTTTPI-----TTTTTVTPTPTPTGTQTPTT 2059

Query: 1547 PPAPRFPLMTKAVTVRGHGS---LPVRTTPL-----QPSLTASPSSRPVASPGAISRSPT 1598
             P      +T   T  G  +    P+ TT        P+ T +P++ P+ +   ++ +PT
Sbjct: 2060 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2119

Query: 1599 SSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTAAE-------QVPVS-P 1650
             +G+     TP  T   + T  P PT   + +  +TP+T   T          Q P + P
Sbjct: 2120 PTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2176

Query: 1651 LATRSLEIVLSTEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQHTTMATRSPALPPETP 1709
            + T +      T  G +   + P+ +  +  P P P+    P   T + T +   P  TP
Sbjct: 2177 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTPTP 2235

Query: 1710 AAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAPVATPGPKASVIT 1769
                  T T     TP  +  +  P+   +G    T+ P+    T  P  TP    +  T
Sbjct: 2236 ------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2289

Query: 1770 TPLQPQATTLP--------AQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATL 1821
            TP+    T  P          T +P+   T    T     T        T    +     
Sbjct: 2290 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2349

Query: 1822 PTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGSAEGGPTE---LTPATS 1878
            PT    P      +  +V P  + TG     +  ++  T++  +     T+    TP T+
Sbjct: 2350 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2409

Query: 1879 HPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLAEAHGTSAGPHLA 1938
                     P G Q  T  P+ T+  ++     T  Q      +        T+  P   
Sbjct: 2410 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT-----TTVTPTPT 2464

Query: 1939 AEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 1981
                   TT P   +               TTT   T+TT  P
Sbjct: 2465 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2507



 Score =  119 bits (298), Expect = 4e-26
 Identities = 133/599 (22%), Positives = 208/599 (34%), Gaps = 57/599 (9%)

Query: 1415 PTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNP-PVTATEEPVVSPGPTQTTLQQPL 1473
            PTP+  +   +     T T  P  TP    T    P   T T  P  +P  TQT    P+
Sbjct: 2095 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2154

Query: 1474 ELTASQLPAGP---TESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRV 1530
              T +  P      T++P +  +T +    P TP     P   QTPT   +     TT  
Sbjct: 2155 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPT----PTGTQTPTTTPI-----TTTT 2204

Query: 1531 TVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGS---LPVRTTPL-----QPSLTASP 1582
            TV    +P  T +  + P      +T   T  G  +    P+ TT        P+ T +P
Sbjct: 2205 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2264

Query: 1583 SSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTA 1642
            ++ P+ +   ++ +PT +G+     TP  T   + T  P PT   + +  +TP+T   T 
Sbjct: 2265 TTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTV 2321

Query: 1643 AE-------QVPVS-PLATRSLEIVLSTEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQ 1693
                     Q P + P+ T +      T  G +   + P+ +  +  P P P+    P  
Sbjct: 2322 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2381

Query: 1694 HTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVG 1753
             T + T +   P  TP      T T     TP  +  +  P+   +G    T+ P+    
Sbjct: 2382 -TPITTTTTVTPTPTP------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2434

Query: 1754 TSAPVATPGPKASVITTPLQPQATTLP--------AQTLSPVLPFTPAAMTQAHPPTHIA 1805
            T  P  TP    +  TTP+    T  P          T +P+   T    T     T   
Sbjct: 2435 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2494

Query: 1806 PPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGS 1865
                 T    +     PT    P      +  +V P  + TG     +  ++  T++  +
Sbjct: 2495 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2554

Query: 1866 AEGGPTE---LTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLL 1922
                 T+    TP T+         P G Q  T  P+ T+  ++     T  Q      +
Sbjct: 2555 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2614

Query: 1923 PQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 1981
                    T+  P          TT P   +               TTT   T+TT  P
Sbjct: 2615 TTT-----TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2668



 Score =  119 bits (298), Expect = 4e-26
 Identities = 133/599 (22%), Positives = 208/599 (34%), Gaps = 57/599 (9%)

Query: 1415 PTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNP-PVTATEEPVVSPGPTQTTLQQPL 1473
            PTP+  +   +     T T  P  TP    T    P   T T  P  +P  TQT    P+
Sbjct: 2256 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2315

Query: 1474 ELTASQLPAGP---TESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRV 1530
              T +  P      T++P +  +T +    P TP     P   QTPT   +     TT  
Sbjct: 2316 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPT----PTGTQTPTTTPI-----TTTT 2365

Query: 1531 TVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGS---LPVRTTPL-----QPSLTASP 1582
            TV    +P  T +  + P      +T   T  G  +    P+ TT        P+ T +P
Sbjct: 2366 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2425

Query: 1583 SSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTA 1642
            ++ P+ +   ++ +PT +G+     TP  T   + T  P PT   + +  +TP+T   T 
Sbjct: 2426 TTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTV 2482

Query: 1643 AE-------QVPVS-PLATRSLEIVLSTEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQ 1693
                     Q P + P+ T +      T  G +   + P+ +  +  P P P+    P  
Sbjct: 2483 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2542

Query: 1694 HTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVG 1753
             T + T +   P  TP      T T     TP  +  +  P+   +G    T+ P+    
Sbjct: 2543 -TPITTTTTVTPTPTP------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2595

Query: 1754 TSAPVATPGPKASVITTPLQPQATTLP--------AQTLSPVLPFTPAAMTQAHPPTHIA 1805
            T  P  TP    +  TTP+    T  P          T +P+   T    T     T   
Sbjct: 2596 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2655

Query: 1806 PPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGS 1865
                 T    +     PT    P      +  +V P  + TG     +  ++  T++  +
Sbjct: 2656 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2715

Query: 1866 AEGGPTE---LTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLL 1922
                 T+    TP T+         P G Q  T  P+ T+  ++     T  Q      +
Sbjct: 2716 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2775

Query: 1923 PQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 1981
                    T+  P          TT P   +               TTT   T+TT  P
Sbjct: 2776 TTT-----TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2829



 Score =  119 bits (298), Expect = 4e-26
 Identities = 133/599 (22%), Positives = 208/599 (34%), Gaps = 57/599 (9%)

Query: 1415 PTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNP-PVTATEEPVVSPGPTQTTLQQPL 1473
            PTP+  +   +     T T  P  TP    T    P   T T  P  +P  TQT    P+
Sbjct: 2417 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2476

Query: 1474 ELTASQLPAGP---TESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRV 1530
              T +  P      T++P +  +T +    P TP     P   QTPT   +     TT  
Sbjct: 2477 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPT----PTGTQTPTTTPI-----TTTT 2526

Query: 1531 TVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGS---LPVRTTPL-----QPSLTASP 1582
            TV    +P  T +  + P      +T   T  G  +    P+ TT        P+ T +P
Sbjct: 2527 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2586

Query: 1583 SSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTA 1642
            ++ P+ +   ++ +PT +G+     TP  T   + T  P PT   + +  +TP+T   T 
Sbjct: 2587 TTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTV 2643

Query: 1643 AE-------QVPVS-PLATRSLEIVLSTEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQ 1693
                     Q P + P+ T +      T  G +   + P+ +  +  P P P+    P  
Sbjct: 2644 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2703

Query: 1694 HTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVG 1753
             T + T +   P  TP      T T     TP  +  +  P+   +G    T+ P+    
Sbjct: 2704 -TPITTTTTVTPTPTP------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2756

Query: 1754 TSAPVATPGPKASVITTPLQPQATTLP--------AQTLSPVLPFTPAAMTQAHPPTHIA 1805
            T  P  TP    +  TTP+    T  P          T +P+   T    T     T   
Sbjct: 2757 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2816

Query: 1806 PPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGS 1865
                 T    +     PT    P      +  +V P  + TG     +  ++  T++  +
Sbjct: 2817 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2876

Query: 1866 AEGGPTE---LTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLL 1922
                 T+    TP T+         P G Q  T  P+ T+  ++     T  Q      +
Sbjct: 2877 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2936

Query: 1923 PQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 1981
                    T+  P          TT P   +               TTT   T+TT  P
Sbjct: 2937 TTT-----TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2990



 Score =  119 bits (298), Expect = 4e-26
 Identities = 133/599 (22%), Positives = 208/599 (34%), Gaps = 57/599 (9%)

Query: 1415 PTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNP-PVTATEEPVVSPGPTQTTLQQPL 1473
            PTP+  +   +     T T  P  TP    T    P   T T  P  +P  TQT    P+
Sbjct: 2578 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2637

Query: 1474 ELTASQLPAGP---TESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRV 1530
              T +  P      T++P +  +T +    P TP     P   QTPT   +     TT  
Sbjct: 2638 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPT----PTGTQTPTTTPI-----TTTT 2687

Query: 1531 TVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGS---LPVRTTPL-----QPSLTASP 1582
            TV    +P  T +  + P      +T   T  G  +    P+ TT        P+ T +P
Sbjct: 2688 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2747

Query: 1583 SSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTA 1642
            ++ P+ +   ++ +PT +G+     TP  T   + T  P PT   + +  +TP+T   T 
Sbjct: 2748 TTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTV 2804

Query: 1643 AE-------QVPVS-PLATRSLEIVLSTEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQ 1693
                     Q P + P+ T +      T  G +   + P+ +  +  P P P+    P  
Sbjct: 2805 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2864

Query: 1694 HTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVG 1753
             T + T +   P  TP      T T     TP  +  +  P+   +G    T+ P+    
Sbjct: 2865 -TPITTTTTVTPTPTP------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2917

Query: 1754 TSAPVATPGPKASVITTPLQPQATTLP--------AQTLSPVLPFTPAAMTQAHPPTHIA 1805
            T  P  TP    +  TTP+    T  P          T +P+   T    T     T   
Sbjct: 2918 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2977

Query: 1806 PPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGS 1865
                 T    +     PT    P      +  +V P  + TG     +  ++  T++  +
Sbjct: 2978 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3037

Query: 1866 AEGGPTE---LTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLL 1922
                 T+    TP T+         P G Q  T  P+ T+  ++     T  Q      +
Sbjct: 3038 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3097

Query: 1923 PQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 1981
                    T+  P          TT P   +               TTT   T+TT  P
Sbjct: 3098 TTT-----TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3151



 Score =  119 bits (298), Expect = 4e-26
 Identities = 133/599 (22%), Positives = 208/599 (34%), Gaps = 57/599 (9%)

Query: 1415 PTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNP-PVTATEEPVVSPGPTQTTLQQPL 1473
            PTP+  +   +     T T  P  TP    T    P   T T  P  +P  TQT    P+
Sbjct: 2739 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2798

Query: 1474 ELTASQLPAGP---TESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRV 1530
              T +  P      T++P +  +T +    P TP     P   QTPT   +     TT  
Sbjct: 2799 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPT----PTGTQTPTTTPI-----TTTT 2848

Query: 1531 TVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGS---LPVRTTPL-----QPSLTASP 1582
            TV    +P  T +  + P      +T   T  G  +    P+ TT        P+ T +P
Sbjct: 2849 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2908

Query: 1583 SSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTA 1642
            ++ P+ +   ++ +PT +G+     TP  T   + T  P PT   + +  +TP+T   T 
Sbjct: 2909 TTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTV 2965

Query: 1643 AE-------QVPVS-PLATRSLEIVLSTEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQ 1693
                     Q P + P+ T +      T  G +   + P+ +  +  P P P+    P  
Sbjct: 2966 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3025

Query: 1694 HTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVG 1753
             T + T +   P  TP      T T     TP  +  +  P+   +G    T+ P+    
Sbjct: 3026 -TPITTTTTVTPTPTP------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3078

Query: 1754 TSAPVATPGPKASVITTPLQPQATTLP--------AQTLSPVLPFTPAAMTQAHPPTHIA 1805
            T  P  TP    +  TTP+    T  P          T +P+   T    T     T   
Sbjct: 3079 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3138

Query: 1806 PPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGS 1865
                 T    +     PT    P      +  +V P  + TG     +  ++  T++  +
Sbjct: 3139 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3198

Query: 1866 AEGGPTE---LTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLL 1922
                 T+    TP T+         P G Q  T  P+ T+  ++     T  Q      +
Sbjct: 3199 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3258

Query: 1923 PQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 1981
                    T+  P          TT P   +               TTT   T+TT  P
Sbjct: 3259 TTT-----TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3312



 Score =  119 bits (298), Expect = 4e-26
 Identities = 133/599 (22%), Positives = 208/599 (34%), Gaps = 57/599 (9%)

Query: 1415 PTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNP-PVTATEEPVVSPGPTQTTLQQPL 1473
            PTP+  +   +     T T  P  TP    T    P   T T  P  +P  TQT    P+
Sbjct: 2900 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2959

Query: 1474 ELTASQLPAGP---TESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRV 1530
              T +  P      T++P +  +T +    P TP     P   QTPT   +     TT  
Sbjct: 2960 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPT----PTGTQTPTTTPI-----TTTT 3009

Query: 1531 TVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGS---LPVRTTPL-----QPSLTASP 1582
            TV    +P  T +  + P      +T   T  G  +    P+ TT        P+ T +P
Sbjct: 3010 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3069

Query: 1583 SSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTA 1642
            ++ P+ +   ++ +PT +G+     TP  T   + T  P PT   + +  +TP+T   T 
Sbjct: 3070 TTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTV 3126

Query: 1643 AE-------QVPVS-PLATRSLEIVLSTEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQ 1693
                     Q P + P+ T +      T  G +   + P+ +  +  P P P+    P  
Sbjct: 3127 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3186

Query: 1694 HTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVG 1753
             T + T +   P  TP      T T     TP  +  +  P+   +G    T+ P+    
Sbjct: 3187 -TPITTTTTVTPTPTP------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3239

Query: 1754 TSAPVATPGPKASVITTPLQPQATTLP--------AQTLSPVLPFTPAAMTQAHPPTHIA 1805
            T  P  TP    +  TTP+    T  P          T +P+   T    T     T   
Sbjct: 3240 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3299

Query: 1806 PPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGS 1865
                 T    +     PT    P      +  +V P  + TG     +  ++  T++  +
Sbjct: 3300 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3359

Query: 1866 AEGGPTE---LTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLL 1922
                 T+    TP T+         P G Q  T  P+ T+  ++     T  Q      +
Sbjct: 3360 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3419

Query: 1923 PQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 1981
                    T+  P          TT P   +               TTT   T+TT  P
Sbjct: 3420 TTT-----TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3473



 Score =  119 bits (298), Expect = 4e-26
 Identities = 133/599 (22%), Positives = 208/599 (34%), Gaps = 57/599 (9%)

Query: 1415 PTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNP-PVTATEEPVVSPGPTQTTLQQPL 1473
            PTP+  +   +     T T  P  TP    T    P   T T  P  +P  TQT    P+
Sbjct: 3061 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3120

Query: 1474 ELTASQLPAGP---TESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRV 1530
              T +  P      T++P +  +T +    P TP     P   QTPT   +     TT  
Sbjct: 3121 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPT----PTGTQTPTTTPI-----TTTT 3170

Query: 1531 TVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGS---LPVRTTPL-----QPSLTASP 1582
            TV    +P  T +  + P      +T   T  G  +    P+ TT        P+ T +P
Sbjct: 3171 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3230

Query: 1583 SSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTA 1642
            ++ P+ +   ++ +PT +G+     TP  T   + T  P PT   + +  +TP+T   T 
Sbjct: 3231 TTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTV 3287

Query: 1643 AE-------QVPVS-PLATRSLEIVLSTEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQ 1693
                     Q P + P+ T +      T  G +   + P+ +  +  P P P+    P  
Sbjct: 3288 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3347

Query: 1694 HTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVG 1753
             T + T +   P  TP      T T     TP  +  +  P+   +G    T+ P+    
Sbjct: 3348 -TPITTTTTVTPTPTP------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3400

Query: 1754 TSAPVATPGPKASVITTPLQPQATTLP--------AQTLSPVLPFTPAAMTQAHPPTHIA 1805
            T  P  TP    +  TTP+    T  P          T +P+   T    T     T   
Sbjct: 3401 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3460

Query: 1806 PPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGS 1865
                 T    +     PT    P      +  +V P  + TG     +  ++  T++  +
Sbjct: 3461 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3520

Query: 1866 AEGGPTE---LTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLL 1922
                 T+    TP T+         P G Q  T  P+ T+  ++     T  Q      +
Sbjct: 3521 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3580

Query: 1923 PQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 1981
                    T+  P          TT P   +               TTT   T+TT  P
Sbjct: 3581 TTT-----TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3634



 Score =  119 bits (298), Expect = 4e-26
 Identities = 133/599 (22%), Positives = 208/599 (34%), Gaps = 57/599 (9%)

Query: 1415 PTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNP-PVTATEEPVVSPGPTQTTLQQPL 1473
            PTP+  +   +     T T  P  TP    T    P   T T  P  +P  TQT    P+
Sbjct: 3222 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3281

Query: 1474 ELTASQLPAGP---TESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRV 1530
              T +  P      T++P +  +T +    P TP     P   QTPT   +     TT  
Sbjct: 3282 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPT----PTGTQTPTTTPI-----TTTT 3331

Query: 1531 TVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGS---LPVRTTPL-----QPSLTASP 1582
            TV    +P  T +  + P      +T   T  G  +    P+ TT        P+ T +P
Sbjct: 3332 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3391

Query: 1583 SSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTA 1642
            ++ P+ +   ++ +PT +G+     TP  T   + T  P PT   + +  +TP+T   T 
Sbjct: 3392 TTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTV 3448

Query: 1643 AE-------QVPVS-PLATRSLEIVLSTEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQ 1693
                     Q P + P+ T +      T  G +   + P+ +  +  P P P+    P  
Sbjct: 3449 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3508

Query: 1694 HTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVG 1753
             T + T +   P  TP      T T     TP  +  +  P+   +G    T+ P+    
Sbjct: 3509 -TPITTTTTVTPTPTP------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3561

Query: 1754 TSAPVATPGPKASVITTPLQPQATTLP--------AQTLSPVLPFTPAAMTQAHPPTHIA 1805
            T  P  TP    +  TTP+    T  P          T +P+   T    T     T   
Sbjct: 3562 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3621

Query: 1806 PPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGS 1865
                 T    +     PT    P      +  +V P  + TG     +  ++  T++  +
Sbjct: 3622 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3681

Query: 1866 AEGGPTE---LTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLL 1922
                 T+    TP T+         P G Q  T  P+ T+  ++     T  Q      +
Sbjct: 3682 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3741

Query: 1923 PQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 1981
                    T+  P          TT P   +               TTT   T+TT  P
Sbjct: 3742 TTT-----TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3795



 Score =  119 bits (298), Expect = 4e-26
 Identities = 133/599 (22%), Positives = 208/599 (34%), Gaps = 57/599 (9%)

Query: 1415 PTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNP-PVTATEEPVVSPGPTQTTLQQPL 1473
            PTP+  +   +     T T  P  TP    T    P   T T  P  +P  TQT    P+
Sbjct: 3383 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3442

Query: 1474 ELTASQLPAGP---TESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRV 1530
              T +  P      T++P +  +T +    P TP     P   QTPT   +     TT  
Sbjct: 3443 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPT----PTGTQTPTTTPI-----TTTT 3492

Query: 1531 TVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGS---LPVRTTPL-----QPSLTASP 1582
            TV    +P  T +  + P      +T   T  G  +    P+ TT        P+ T +P
Sbjct: 3493 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3552

Query: 1583 SSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTA 1642
            ++ P+ +   ++ +PT +G+     TP  T   + T  P PT   + +  +TP+T   T 
Sbjct: 3553 TTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTV 3609

Query: 1643 AE-------QVPVS-PLATRSLEIVLSTEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQ 1693
                     Q P + P+ T +      T  G +   + P+ +  +  P P P+    P  
Sbjct: 3610 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3669

Query: 1694 HTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVG 1753
             T + T +   P  TP      T T     TP  +  +  P+   +G    T+ P+    
Sbjct: 3670 -TPITTTTTVTPTPTP------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3722

Query: 1754 TSAPVATPGPKASVITTPLQPQATTLP--------AQTLSPVLPFTPAAMTQAHPPTHIA 1805
            T  P  TP    +  TTP+    T  P          T +P+   T    T     T   
Sbjct: 3723 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3782

Query: 1806 PPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGS 1865
                 T    +     PT    P      +  +V P  + TG     +  ++  T++  +
Sbjct: 3783 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3842

Query: 1866 AEGGPTE---LTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLL 1922
                 T+    TP T+         P G Q  T  P+ T+  ++     T  Q      +
Sbjct: 3843 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3902

Query: 1923 PQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 1981
                    T+  P          TT P   +               TTT   T+TT  P
Sbjct: 3903 TTT-----TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3956



 Score =  119 bits (298), Expect = 4e-26
 Identities = 133/599 (22%), Positives = 208/599 (34%), Gaps = 57/599 (9%)

Query: 1415 PTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNP-PVTATEEPVVSPGPTQTTLQQPL 1473
            PTP+  +   +     T T  P  TP    T    P   T T  P  +P  TQT    P+
Sbjct: 3544 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3603

Query: 1474 ELTASQLPAGP---TESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRV 1530
              T +  P      T++P +  +T +    P TP     P   QTPT   +     TT  
Sbjct: 3604 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPT----PTGTQTPTTTPI-----TTTT 3653

Query: 1531 TVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGS---LPVRTTPL-----QPSLTASP 1582
            TV    +P  T +  + P      +T   T  G  +    P+ TT        P+ T +P
Sbjct: 3654 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3713

Query: 1583 SSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTA 1642
            ++ P+ +   ++ +PT +G+     TP  T   + T  P PT   + +  +TP+T   T 
Sbjct: 3714 TTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTV 3770

Query: 1643 AE-------QVPVS-PLATRSLEIVLSTEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQ 1693
                     Q P + P+ T +      T  G +   + P+ +  +  P P P+    P  
Sbjct: 3771 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3830

Query: 1694 HTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVG 1753
             T + T +   P  TP      T T     TP  +  +  P+   +G    T+ P+    
Sbjct: 3831 -TPITTTTTVTPTPTP------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3883

Query: 1754 TSAPVATPGPKASVITTPLQPQATTLP--------AQTLSPVLPFTPAAMTQAHPPTHIA 1805
            T  P  TP    +  TTP+    T  P          T +P+   T    T     T   
Sbjct: 3884 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3943

Query: 1806 PPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGS 1865
                 T    +     PT    P      +  +V P  + TG     +  ++  T++  +
Sbjct: 3944 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 4003

Query: 1866 AEGGPTE---LTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLL 1922
                 T+    TP T+         P G Q  T  P+ T+  ++     T  Q      +
Sbjct: 4004 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 4063

Query: 1923 PQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 1981
                    T+  P          TT P   +               TTT   T+TT  P
Sbjct: 4064 TTT-----TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 4117



 Score =  119 bits (297), Expect = 6e-26
 Identities = 139/580 (23%), Positives = 226/580 (38%), Gaps = 108/580 (18%)

Query: 403  CEFHGTLYPPGSVVKEDCNTC---TCTSG--------------KWECSTAVCPAECSVTG 445
            C+++ T+     +VK +C      TC++G               WEC        C+  G
Sbjct: 4435 CKYNNTV----EIVKVECEPPPMPTCSNGLQPVRVEDPDGCCWHWECD-----CYCTGWG 4485

Query: 446  DIHFTTFDGRRYTFPATCQYILAK--SRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQ 503
            D H+ TFDG  Y++   C Y+L +  S S   F V + N  C  N   +C +++ ++ H+
Sbjct: 4486 DPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSCPRTL-IVRHE 4544

Query: 504  DPR---RQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREG 560
                  + V +      +  ++  +  PY     E+ +    ++     +GV V Y+  G
Sbjct: 4545 TQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVLVSYN--G 4602

Query: 561  LRLYLQVD-QRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLV- 618
            L   +++   R+  +T G CGT    T DD + P G   S  +   + W       P   
Sbjct: 4603 LSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCP 4662

Query: 619  -SGSPLDPCDVHLQAASYSV--------QACSVLTGEMFAPCSAFLSPVPYFEQCRRDAC 669
             S S      V +     +           C ++   +FA C A + P  Y++ C  D+C
Sbjct: 4663 HSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSC 4722

Query: 670  -RCGQPCLCATLAHYAHLCRRHGLPVDFRARL-PACALSCEASKEYSPCVAPCGRTCQDL 727
               G    CA+L  YA LC +  + +D+R     AC + C + +EY  C      TC+  
Sbjct: 4723 FMPGSSLECASLQAYAALCAQQNICLDWRNHTHGACLVECPSHREYQACGPAEEPTCKSS 4782

Query: 728  ASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQA-DLCVPRNQCSCHFQGVDYPP---G 783
            +S +          +    VEGC CP  T       D+CV    C C   G D  P   G
Sbjct: 4783 SSQQ----------NNTVLVEGCFCPEGTMNYAPGFDVCV--KTCGC--VGPDNVPREFG 4828

Query: 784  DSDIPSLGHCHCKDG--VMSCD----SRAPAAACPAGQVF----VNCSDLHTDLELSRER 833
            +       +C C +G   + C     S+ P   C     +    VN +D   ++ + +  
Sbjct: 4829 EHFEFDCKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTCCNITVCKCN 4888

Query: 834  T--CEQQ--LLNLSVSARGPCLSGCACP------QGLLRHGDACFLPEECPCTWKGKEYF 883
            T  C+++  +  L    +   + G  CP      +G+  HG+A              EY 
Sbjct: 4889 TSLCKEKPSVCPLGFEVKSKMVPGRCCPFYWCESKGVCVHGNA--------------EYQ 4934

Query: 884  PGDQV-MSPCHTCVCQ--------RGSFQCTLHPCASTCT 914
            PG  V  S C  CVC              CT  PC ++C+
Sbjct: 4935 PGSPVYSSKCQDCVCTDKVDNNTLLNVIACTHVPCNTSCS 4974



 Score =  115 bits (289), Expect = 5e-25
 Identities = 109/399 (27%), Positives = 155/399 (38%), Gaps = 49/399 (12%)

Query: 74   ERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTC 133
            E D  C  WG  H  TFDGLYY   G  +Y LV    P   +F + + N     +   +C
Sbjct: 4476 ECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSC 4535

Query: 134  SRAVSLFFVGEQEIHLAKEVTHGGMRVQ---------LPH-VMGSARLQQLAGYVIVRHQ 183
             R  +L    E +  L K V    M+VQ         LP+   G    Q    YV+   +
Sbjct: 4536 PR--TLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPE 4593

Query: 184  SAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQE 243
                ++++G S             T G CG       DD +  SG++  +       W  
Sbjct: 4594 LGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLV 4653

Query: 244  QAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQ------CEALLRPPFDACHAYVSPLPF 297
              P++P  P +SS  + P +    G     ++       C+ +    F  CHA V P  +
Sbjct: 4654 NDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHY 4713

Query: 298  TASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLR-QCTVHCKEKAFTYNE 356
              +C  D C   G  +  C +L  YA  CAQ    L  WR      C V C     ++ E
Sbjct: 4714 YDACVFDSCFMPGS-SLECASLQAYAALCAQQNICLD-WRNHTHGACLVECP----SHRE 4767

Query: 357  CIACCPA---SCHPRASCVDSEIACVDGCYCPNG---------LIFEDGGCVAPAECPCE 404
              AC PA   +C   +S  ++ +  V+GC+CP G         +  +  GCV P   P E
Sbjct: 4768 YQACGPAEEPTCKSSSSQQNNTV-LVEGCFCPEGTMNYAPGFDVCVKTCGCVGPDNVPRE 4826

Query: 405  FHGTLYPPGSVVKEDCNTCTCTSGKWECSTAVC-PAECS 442
            F       G   + DC  C C  G    S  +C P  CS
Sbjct: 4827 F-------GEHFEFDCKNCVCLEGG---SGIICQPKRCS 4855



 Score =  112 bits (281), Expect = 4e-24
 Identities = 147/644 (22%), Positives = 226/644 (35%), Gaps = 78/644 (12%)

Query: 1385 CVYLEDCV---EPAVWVPTEALGNETLPPSQGLPTP----SDEEPQLSQESP---RTPTH 1434
            C  ++ C+    P    P+    + T  P    P+P    +   P  +  SP    T T 
Sbjct: 1389 CWPMDKCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTP 1448

Query: 1435 RPALTPAAPLTTALNPPVTATEEP-VVSPGPTQTTLQQPLELTASQLPAGPTESPASKGV 1493
             P  TP+ P++T   PP T T  P   +P P  TT   P   T +  P      P +  +
Sbjct: 1449 PPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPI 1508

Query: 1494 T--ASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPR 1551
            T  AS   +P T   S       TP P        TT +T   + +     ++ SPP   
Sbjct: 1509 TPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPP--- 1565

Query: 1552 FPLMTKAVTVRGHGSLPVRTTPLQPSLTAS--PSSRPVASPGAISRSPTSSGSHKAVLTP 1609
             P  T         S P  TTP  P++T +  P +   + P   + +P  + +     T 
Sbjct: 1566 -PTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTT 1624

Query: 1610 AVTKVISRTGVPQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGH 1669
             +T   S T +P  T      +PS P T   T       SP  T +              
Sbjct: 1625 PITPPTSTTTLPPTT------TPSPPPTTTTTPPPTTTPSPPTTTT-------------P 1665

Query: 1670 SQPMGSPASPQPHPLPSAP----PRPAQHTTMATRSPALPPETPAAASLSTATDGLAATP 1725
            S P+ +  +P P   PS+P    P P   TTM T SP   P +P   + + ++    + P
Sbjct: 1666 SPPITTTTTPPPTTTPSSPITTTPSPPT-TTMTTPSPTTTPSSPITTTTTPSSTTTPSPP 1724

Query: 1726 FMSLESTRPSQLLSGLPPDTSL-PLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTL 1784
              ++  T PS   +  PP T++  L    TS+P+ T     S+      P +TT P    
Sbjct: 1725 PTTM--TTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPC 1782

Query: 1785 SPVLPFT---PAAMTQAHPP---THIAPPAAGT--APGLLLGATLPTS------GVLPVA 1830
             P+  +T    +     H P   T +     G   A  +   AT+         G   V 
Sbjct: 1783 VPLCNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANISCRATMYPDVPIGQLGQTVVC 1842

Query: 1831 EGTASMVSVVPRKSTTGKVAI-----------LSKQVSLPTSMYGSAEGGPT--ELTPAT 1877
            + +  ++     +   G + +             + V+ PT+M  +    PT    TP T
Sbjct: 1843 DVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPIT 1902

Query: 1878 SHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLAEAHGTSAGPHL 1937
            +         P G Q  T  P+ T+  ++     T  Q      +        T+  P  
Sbjct: 1903 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT-----TTVTPTP 1957

Query: 1938 AAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 1981
                    TT P   +               TTT   T+TT  P
Sbjct: 1958 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2001



 Score =  109 bits (273), Expect = 3e-23
 Identities = 178/764 (23%), Positives = 253/764 (33%), Gaps = 116/764 (15%)

Query: 1336 CEWRYDACASPCFQTCRDPRAASCR-DVPRVEGCVPVCPTPQ-VLDEVTQRCV------- 1386
            CEW Y+ C +  F+TCR          V  +EGC P CP  + + +E  ++CV       
Sbjct: 1130 CEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGC 1189

Query: 1387 YLEDC-VEPAVWVPT-EALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPL 1444
            Y+ED    P   VPT E   +     S  +    +E   L+Q       +     P   +
Sbjct: 1190 YVEDTHYPPGASVPTEETCKSCVCTNSSQVVCRPEEGKILNQTQDGAFCYWEICGPNGTV 1249

Query: 1445 TTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTP 1504
                N     T    ++   T T    P   T +     PT S            +  TP
Sbjct: 1250 EKHFNICSITTRPSTLTTFTTITLPTTPTTFTTTTTTTTPTSSTV----------LSTTP 1299

Query: 1505 ESSSLP---VALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTV 1561
            +   L    +    P+ G   G  ET        G+P   +  RS   P   L      V
Sbjct: 1300 KLCCLWSDWINEDHPSSGSDDGDRETFDGV---CGAPE-DIECRSVKDPHLSLEQLGQKV 1355

Query: 1562 R---------------GHGSLPVRTTPLQPSLTASPSSRPVASPGAISRSPTSSGSHKAV 1606
            +               G+G   +            P  + + +P   + +P+   +    
Sbjct: 1356 QCDVSVGFICKNEDQFGNGPFGLCYDYKIRVNCCWPMDKCITTPSPPTTTPSPPPTSTTT 1415

Query: 1607 LTPAVTKV--ISRTGVPQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEK 1664
            L P  T     + T  P PT     ++PS P+T   T       SP         +ST  
Sbjct: 1416 LPPTTTPSPPTTTTTTPPPT-----TTPSPPITTTTTPPPTTTPSP--------PISTTT 1462

Query: 1665 GEAGHSQPMGSPASPQPHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAAT 1724
                 + P     +P P     +PP     T   T +P+ P  TP     ST T     T
Sbjct: 1463 TPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTT 1522

Query: 1725 PF-MSLESTRPSQLLSGLPPDTS--LPLAKVGTSAPVATPGPKASVITTPLQPQATTLPA 1781
            P   +  +T P    +  PP T+   P     T  P  TP P  +  TTP  P  T  P 
Sbjct: 1523 PSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTP-PPTTTPSPP 1581

Query: 1782 QTLSPVLP----FTPAAMTQAHPPTHIA---PPAAGTAPGLLLGATLPTSGVLPVAEGTA 1834
             T +P  P     TP   T   PPT      PP    +P      T PTS        T 
Sbjct: 1582 TTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTP 1641

Query: 1835 S---MVSVVPRKSTTGKVAILSKQVSLPTSMYGSAEGGPTELTPATSHPLTPLVAEPEGA 1891
            S     +  P  +TT          S PT+   S     T   P T+ P +P+   P   
Sbjct: 1642 SPPPTTTTTPPPTTT---------PSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPP 1692

Query: 1892 QAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLAEAHGTSAGPHLAAEP--VDEATTEP 1949
                  P PT+   S ++  T P  +     P       T+  P     P      T  P
Sbjct: 1693 TTTMTTPSPTTTPSSPITTTTTPSST---TTPSPPPTTMTTPSPTTTPSPPTTTMTTLPP 1749

Query: 1950 SGRSAPAL------SIVEGLAEALATTTEANTSTTCVPIAEQDCVRHICLEGQLIRVNQS 2003
            +  S+P        SI        +TTT    +T CVP+            G L     +
Sbjct: 1750 TTTSSPLTTTPLPPSITPPTFSPFSTTT---PTTPCVPLCN--------WTGWLDSGKPN 1798

Query: 2004 QHCPQGAAPPRCGILGLAVRVGGDRCCPLW--ECACRCSIFPDL 2045
             H P G              + GD C P W    +CR +++PD+
Sbjct: 1799 FHKPGG-----------DTELIGDVCGPGWAANISCRATMYPDV 1831



 Score = 93.6 bits (231), Expect = 3e-18
 Identities = 118/550 (21%), Positives = 186/550 (33%), Gaps = 76/550 (13%)

Query: 1443 PLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPH 1502
            P+   LN  +       V+   T TT       T ++ P  PT +P +   T        
Sbjct: 1862 PMAFCLNYEINVQCCECVTQPTTMTT-------TTTENPTPPTTTPITTTTTV------- 1907

Query: 1503 TPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVR 1562
            TP  +  P   QTPT         TT +T     +P  T     P   + P  T   T  
Sbjct: 1908 TPTPT--PTGTQTPT---------TTPITTTTTVTPTPT-----PTGTQTPTTTPITT-- 1949

Query: 1563 GHGSLPVRTTPLQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQ 1622
               +  V  TP  P+ T +P++ P+ +   ++ +PT +G+     TP  T   + T  P 
Sbjct: 1950 ---TTTVTPTPT-PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPT 2002

Query: 1623 PTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPH 1682
            PT   + +  +TP+T   T    V  +P  T +          +   + P+ +  +  P 
Sbjct: 2003 PTPTGTQTPTTTPITTTTT----VTPTPTPTGT----------QTPTTTPITTTTTVTPT 2048

Query: 1683 PLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLP 1742
            P P+    P   T + T +   P  TP      T T     TP  +  +  P+   +G  
Sbjct: 2049 PTPTGTQTPTT-TPITTTTTVTPTPTP------TGTQTPTTTPITTTTTVTPTPTPTGTQ 2101

Query: 1743 PDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLP--------AQTLSPVLPFTPAA 1794
              T+ P+    T  P  TP    +  TTP+    T  P          T +P+   T   
Sbjct: 2102 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2161

Query: 1795 MTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSK 1854
             T     T        T    +     PT    P      +  +V P  + TG     + 
Sbjct: 2162 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2221

Query: 1855 QVSLPTSMYGSAEGGPTE---LTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSAR 1911
             ++  T++  +     T+    TP T+         P G Q  T  P+ T+  ++     
Sbjct: 2222 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2281

Query: 1912 TAPQDSMLVLLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTT 1971
            T  Q      +        T+  P          TT P   +               TTT
Sbjct: 2282 TGTQTPTTTPITTT-----TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2336

Query: 1972 EANTSTTCVP 1981
               T+TT  P
Sbjct: 2337 PITTTTTVTP 2346



 Score = 75.5 bits (184), Expect = 7e-13
 Identities = 70/313 (22%), Positives = 118/313 (37%), Gaps = 46/313 (14%)

Query: 904  CTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVK--STSDVSFSVIVENVNCYSSG 961
            C    C   CT +GD HY TFDGL + + G C   LV+  S S  +F V ++N +C  + 
Sbjct: 4472 CWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPND 4531

Query: 962  MI-CRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEV---------HTWRVGFFTLVHF 1011
             + C + + +      ++       P       ++Q V           ++ G   +V  
Sbjct: 4532 KVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDI 4591

Query: 1012 PQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSW 1071
            P+  + + ++  +        ++     G CG     T ++   P    ++N +     W
Sbjct: 4592 PELGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQW 4651

Query: 1072 AAVE-----CPDTLD----------------PRDMCVLNPLREPFAKKECSILLSEVFEI 1110
               +     CP +                  P   C  +PL        C ++   +F  
Sbjct: 4652 LVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPL--------CQLIKDSLFAQ 4703

Query: 1111 CHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWR--TPRLCPY 1168
            CH +V    +Y  C+ D+C    G   EC  AS+ AYA  C Q  + +DWR  T   C  
Sbjct: 4704 CHALVPPQHYYDACVFDSC-FMPGSSLEC--ASLQAYAALCAQQNICLDWRNHTHGACLV 4760

Query: 1169 DCDFFNKVLGKGP 1181
            +C    +    GP
Sbjct: 4761 ECPSHREYQACGP 4773



 Score = 67.4 bits (163), Expect = 2e-10
 Identities = 89/398 (22%), Positives = 145/398 (36%), Gaps = 67/398 (16%)

Query: 2030 CPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDC-KSANLGHL 2088
            C    C   CSI+    ++TFDG +        Y+  Q            C ++++LG  
Sbjct: 851  CTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDY----------CGQNSSLGS- 899

Query: 2089 NWPPFCLVMLNM----THLAHQVTIDRFNRKVTVDLQPVWPPVSR------YGFRIEDTG 2138
                F ++  N+    T +     I  F  +  + L+     V +        +   + G
Sbjct: 900  ----FSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYTTREVG 955

Query: 2139 HMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGA 2198
               ++ + + I + W      + ++ + + K    GLCG  D  + ND T +D  VV   
Sbjct: 956  QYLVVESSTGIIVIW-DKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSE 1014

Query: 2199 EDPAPFLDSWQVPSSLTSVGQTRFRPDSC---------ATTDCSPCLRMVSNRTFSACHR 2249
             D   F +SW+   +   V      P+ C         A   CS    ++ +  FS CH 
Sbjct: 1015 LD---FGNSWKEAPTCPDVSTN---PEPCSLNPHRRSWAEKQCS----ILKSSVFSICHS 1064

Query: 2250 FVPPESFCELWIRDTKYVQQP------CVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSD 2303
             V P+ F E  + D+            C A+  Y   C K   C+ WR  D CP  C   
Sbjct: 1065 KVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACVFWRTPDLCPIFCDYY 1124

Query: 2304 STYQACVTACEPP-----KTCQ--DGILGPLDPEHCQVLGEGCV--CSEGTILHRRHSAL 2354
            +    C    EP      +TC+  +GI   +   +     EGC   C +   ++      
Sbjct: 1125 NPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYL----EGCYPRCPKDRPIYEEDLKK 1180

Query: 2355 CIPEAKCAC--TDSMGVPRALGETWNSSLSGCCQHQCQ 2390
            C+   KC C   D+   P A   T  +  S  C +  Q
Sbjct: 1181 CVTADKCGCYVEDTHYPPGASVPTEETCKSCVCTNSSQ 1218



 Score = 55.8 bits (133), Expect = 6e-07
 Identities = 92/411 (22%), Positives = 146/411 (35%), Gaps = 61/411 (14%)

Query: 1979 CVPIAEQDCVRH--ICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECA 2036
            CVP+++  C  H  +   GQ I  N  + C   A               G   C    C 
Sbjct: 345  CVPVSQCHCRLHGHLYTPGQEI-TNDCEQCVCNA---------------GRWVCKDLPCP 388

Query: 2037 CRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLV 2096
              C++       TFDG       +  Y+L++        + L  + A  G  +       
Sbjct: 389  GTCALEGGSHITTFDGKTYTFHGDCYYVLAKGDHN--DSYALLGELAPCGSTDKQTCLKT 446

Query: 2097 MLNMTHLAHQVTIDRFNRKVTV-DLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQ-WL 2154
            ++ +      V + + +  V + +LQ   P V+        + +  M+     +++Q  L
Sbjct: 447  VVLLADKKKNVVVFKSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQL 506

Query: 2155 HSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSL 2214
                 + V   + S+ Q  GLCG  +G   +D     G V       A F ++W+  SS 
Sbjct: 507  APVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATG---AGFANTWKAQSSC 563

Query: 2215 TSVGQTRFRPDSCATTDCSP------CLRMVSNRT-FSACHRFVPPESFCELWIRDTKYV 2267
                +  +  D C+    S       C  +    T F  CH  V P  + +    DT   
Sbjct: 564  HD--KLDWLDDPCSLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNC 621

Query: 2268 QQP----CVALTVYVAMCHKFHVCI-EWRRS------DYCP----FLCSSDSTYQACVTA 2312
            Q      C AL+ Y   C    V +  WR          CP    FL +  +  Q C + 
Sbjct: 622  QNNEDCLCAALSSYARACTAKGVMLWGWREHVCNKDVGSCPNSQVFLYNLTTCQQTCRSL 681

Query: 2313 CEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCAC 2363
             E    C +G   P+D         GC C + T L  +    C+P AKC+C
Sbjct: 682  SEADSHCLEG-FAPVD---------GCGCPDHTFLDEK--GRCVPLAKCSC 720



 Score = 55.5 bits (132), Expect = 8e-07
 Identities = 58/242 (23%), Positives = 93/242 (38%), Gaps = 22/242 (9%)

Query: 2131 GFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLT 2188
            G  IE +     + + + + + W     LM+      +K + H  GLCG  +G  +    
Sbjct: 125  GLLIEKSDAYTKVYSRAGLTLMWNREDALML---ELDTKFRNHTCGLCGDYNGLQSYSEF 181

Query: 2189 LKDGSVVGGAEDPAPFLDSWQV--PSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRTFSA 2246
            L DG +      P  F +  ++  P  +    +    P SC+      C R+++   F+ 
Sbjct: 182  LSDGVLFS----PLEFGNMQKINQPDVVCEDPEEEVAPASCSEHRAE-CERLLTAEAFAD 236

Query: 2247 CHRFVPPESFCELWIRDTKYVQ--QPCVALTV--YVAMC-HKFHVCIEWRRSDYCPFLCS 2301
            C   VP E +     +D         CV  TV  +   C H       WR +  CP  C 
Sbjct: 237  CQDLVPLEPYLRACQQDRCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATLCPKTCP 296

Query: 2302 SDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKC 2361
             +  Y    + C    TC    +  L  EH     +GC C EGT+      + C+P ++C
Sbjct: 297  GNLVYLESGSPCMD--TCSHLEVSSLCEEHRM---DGCFCPEGTVYDDIGDSGCVPVSQC 351

Query: 2362 AC 2363
             C
Sbjct: 352  HC 353



 Score = 49.3 bits (116), Expect = 5e-05
 Identities = 77/325 (23%), Positives = 110/325 (33%), Gaps = 77/325 (23%)

Query: 1409 PPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTT 1468
            P   G  TP+      +     TPT     TP          P+T T     +P PT T 
Sbjct: 4142 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-------TTPITTTTTVTPTPTPTGTQ 4194

Query: 1469 LQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETT 1528
               P   + + +    T +P  +  T      P T  S+S P+               T 
Sbjct: 4195 TGPPTHTSTAPIAELTTSNPPPESST------PQTSRSTSSPL---------------TE 4233

Query: 1529 RVTVIFAGSPNITVSSRSPPA-PRFPLMTKAVTVRGHGSLPVRTTPLQPSLTASPSSRPV 1587
              T++    P I ++S +PP+ P  P  T      GH   P       PS T SP     
Sbjct: 4234 STTLLSTLPPAIEMTSTAPPSTPTAPTTTSG----GHTLSP------PPSTTTSP----- 4278

Query: 1588 ASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTAAEQVP 1647
              PG  +R  T++GS  A     V    +    P PT        STP  +  T     P
Sbjct: 4279 --PGTPTRG-TTTGSSSAPTPSTVQTTTTSAWTPTPTPL------STPSIIRTTGLRPYP 4329

Query: 1648 VSPLATRSLEIVLSTEKGEAGHSQPMGS--------------------PASPQPHPLPS- 1686
             S L    L        GE  ++   G                     P++P P P PS 
Sbjct: 4330 SSVLICCVLNDTYYA-PGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSK 4388

Query: 1687 APPRPAQHTTMATRSP--ALPPETP 1709
            + P P++ ++  ++      PPE P
Sbjct: 4389 STPTPSKPSSTPSKPTPGTKPPECP 4413


>gi|169202626 PREDICTED: similar to mucin 5, partial [Homo sapiens]
          Length = 2013

 Score =  612 bits (1577), Expect = e-174
 Identities = 381/1126 (33%), Positives = 548/1126 (48%), Gaps = 65/1126 (5%)

Query: 78   ICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAV 137
            +C  WG  H +TFDG  +   G  +Y          + F+IQ+    +  S+  T SR  
Sbjct: 80   VCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQE--SAAPTLSRV- 136

Query: 138  SLFFVGEQEIHLAK-EVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAV 196
             L  V    I L K  V   G  V LP       +QQ + Y  V  +    L W+   ++
Sbjct: 137  -LMKVDGVVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKVEARLGLVLMWNHDDSL 195

Query: 197  YIKMSPELLGWTHGLCGNNNADPK-DDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTS 255
             +++  +    T GLCG+ N  P   +L++ + KLT   +EF +    Q  + P      
Sbjct: 196  LLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTP--MEFGNL---QKMDDPTEQCQD 250

Query: 256  SLPRPPCLQQNPGTMQGVYEQCEALLRPP-FDACHAYVSPLPFTASCTSDLC--QSMGDV 312
             +P PP   +N  T  G+   CE LL    F  C A V    +  +C  DLC  +    +
Sbjct: 251  PVPEPP---RNCSTGFGI---CEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLL 304

Query: 313  ATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCV 372
            +  C  LAEY+R C  AG   Q WR     C   C      Y+EC + C  +C  +    
Sbjct: 305  SCVCHTLAEYSRQCTHAGGLPQDWRGP-DFCPQKCPNN-MQYHECRSPCADTCSNQEHSR 362

Query: 373  DSEIACVDGCYCPNGLIFED---GGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGK 429
              E  CV GC+CP G + +D    GCV  ++C C ++G  Y PG+    DC  CTC+ G+
Sbjct: 363  ACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYSTDCTNCTCSGGR 422

Query: 430  WECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQ 489
            W C    CP  CSV G  HF+TFDG++YT    C Y+L K   S  FTV  +   CGL  
Sbjct: 423  WSCQEVPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCGLTD 482

Query: 490  DGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTN 549
               C++SV++ L    +  V +  +G+V L   Y  +P    +   I R S+ F+  +T+
Sbjct: 483  SETCLKSVTLSL-DGVQTVVVIKASGEVFLNQIYTQLPISAANV-TIFRPSTFFIIAQTS 540

Query: 550  VGVRV-LYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSW 608
            +G+++ L     ++L++Q+  +    T GLCG FN    DDF +  GV E+T   F N++
Sbjct: 541  LGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTF 600

Query: 609  KTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGE--MFAPCSAFLSPVPYFEQCRR 666
            KT +AC P +  S  DPC + ++   Y+   CS LT     F  C A + P  Y+  C  
Sbjct: 601  KTQAAC-PNIRNSFEDPCSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMF 659

Query: 667  DACRC--GQPCLCATLAHYAHLCRRHGLPVDFRARLPACA---LSCEASKEYSPCVAPCG 721
            D C C   + CLCA L+ Y H C   G+ +    R   C     +C  S  Y   V+ C 
Sbjct: 660  DTCNCERSEDCLCAALSSYVHACAAKGVQLG-GWRDGVCTKPMTTCPKSMTYHYHVSTCQ 718

Query: 722  RTCQDLASPE-ACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDY 780
             TC+ L+  +  C V           V+GC CP  T+LD     CV  + C C+ +G   
Sbjct: 719  PTCRSLSEGDITCSVGFIP-------VDGCICPKGTFLDDTGK-CVQASNCPCYHRGSMI 770

Query: 781  PPGDSDIPSLGHCHCKDGVMSC-DSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQL 839
            P G+S   S   C C  G +SC   +APA  C A  VF +C +            C++  
Sbjct: 771  PNGESVHDSGAICTCTHGKLSCIGGQAPAPVCAAPMVFFDCRNATPG---DTGAGCQKSC 827

Query: 840  LNLSVSARGP-CLSGCACPQGLLRHGDA-CFLPEECPCTWKGKEYFPGDQVMSPCHTCVC 897
              L ++   P C+ GC CP GL+  G+  C   E+CPC      Y  G  +   C+TC C
Sbjct: 828  HTLDMTCYSPQCVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRVGCNTCTC 887

Query: 898  QRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLV------KSTSDVSFSVI 951
                ++CT  PC +TC  YGD HY TFDG  + F G C+  LV      K ++  SF V+
Sbjct: 888  DSRMWRCTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVV 947

Query: 952  VENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESF-LDDKQEV-HTWRVGFFTLV 1009
             ENV C ++G  C K I I +G     F+    +   E    D+ QEV +T R     LV
Sbjct: 948  TENVPCGTTGTTCSKAIKIFLGG----FELKLSHGKVEVIGTDESQEVPYTIRQMGIYLV 1003

Query: 1010 HFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGS 1069
                  + LLWD++T++ +   P+++G++ GLCGNFD   +N+  T     + +  EFG+
Sbjct: 1004 VDTDIGLVLLWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGN 1063

Query: 1070 SWA-AVECPDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDT 1128
            SW  +  CPD L P+D C  NP R+ +A+K+CSIL    F  CH  V+   +Y  C+ D 
Sbjct: 1064 SWKLSPSCPDALAPKDPCTANPFRKSWAQKQCSILHGPTFAACHAHVEPARYYEACVNDA 1123

Query: 1129 CGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFN 1174
            C C  GGDCECFC +V+AYA  C + G+ V WRTP +CP  CD++N
Sbjct: 1124 CACDSGGDCECFCTAVAAYAQACHEVGLCVSWRTPSICPLFCDYYN 1169



 Score =  231 bits (590), Expect = 6e-60
 Identities = 152/486 (31%), Positives = 221/486 (45%), Gaps = 62/486 (12%)

Query: 359  ACCPASCHPR-ASCVDSEIACVDGCYCPNGLIFE-DGGCVAPAECPCEFHGTLYPPGSVV 416
            A C  SCH    +C   +  CV GC CP+GL+ + +GGC+   +CPC  +   Y  G  +
Sbjct: 821  AGCQKSCHTLDMTCYSPQ--CVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTI 878

Query: 417  KEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSG-- 474
            +  CNTCTC S  W C+   C A C+V GD H+ TFDG+ Y+F   C+Y L ++   G  
Sbjct: 879  RVGCNTCTCDSRMWRCTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKD 938

Query: 475  ----TFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYT 530
                +F V  +N PCG      C +++ + L             G  L     K+    T
Sbjct: 939  STQDSFRVVTENVPCGTTGT-TCSKAIKIFL------------GGFELKLSHGKVEVIGT 985

Query: 531  DDAFEIR---RLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQ 587
            D++ E+    R   ++L V T++G+ +L+D++   +++ +   +     GLCG F+    
Sbjct: 986  DESQEVPYTIRQMGIYLVVDTDIGLVLLWDKK-TSIFINLSPEFKGRVCGLCGNFDDIAV 1044

Query: 588  DDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEM 647
            +DF +           FGNSWK   +C   ++  P DPC  +    S++ + CS+L G  
Sbjct: 1045 NDFATRSRSVVGDVLEFGNSWKLSPSCPDALA--PKDPCTANPFRKSWAQKQCSILHGPT 1102

Query: 648  FAPCSAFLSPVPYFEQCRRDACRCGQ----PCLCATLAHYAHLCRRHGLPVDFRARLPAC 703
            FA C A + P  Y+E C  DAC C       C C  +A YA  C   GL V +R     C
Sbjct: 1103 FAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCVSWRTP-SIC 1161

Query: 704  ALSCE-------ASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGC--ACPP 754
             L C+           Y PC  PC RTC++           GD L     +EGC   CPP
Sbjct: 1162 PLFCDYYNPEGQCEWHYQPCGVPCLRTCRN---------PRGDCLRDVWGLEGCYPKCPP 1212

Query: 755  DT-YLDTQADLCV-----PRNQCSCHFQGVDYPPGDSDIPSLGHCH---CKDGVMSCDSR 805
            +    D     CV     P     CH  G  Y PG + +PS  +C    C +  + C  +
Sbjct: 1213 EAPIFDEDKMQCVATCPTPPLPPRCHVHGKSYRPG-AVVPSDKNCQSCLCTERGVECTYK 1271

Query: 806  APAAAC 811
            A A  C
Sbjct: 1272 AEACVC 1277



 Score =  184 bits (468), Expect = 8e-46
 Identities = 136/449 (30%), Positives = 201/449 (44%), Gaps = 68/449 (15%)

Query: 53   CDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRH--- 109
            CD R +  T   C           + C  +G  H  TFDG  Y  +G   YTLV  H   
Sbjct: 887  CDSRMWRCTDDPCL----------ATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGG 936

Query: 110  -EPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRV-------Q 161
             +    SF +   N P CG++  TCS+A+ +F  G +      +++HG + V       +
Sbjct: 937  KDSTQDSFRVVTENVP-CGTTGTTCSKAIKIFLGGFE-----LKLSHGKVEVIGTDESQE 990

Query: 162  LPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKD 221
            +P+      ++Q+  Y++V       L WD  ++++I +SPE  G   GLCGN +    +
Sbjct: 991  VPYT-----IRQMGIYLVVDTDIGLVLLWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVN 1045

Query: 222  DLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALL 281
            D  T S  +  DV+EF +SW+       P    +  P+ PC   NP       +QC  L 
Sbjct: 1046 DFATRSRSVVGDVLEFGNSWKLS-----PSCPDALAPKDPCTA-NPFRKSWAQKQCSILH 1099

Query: 282  RPPFDACHAYVSPLPFTASCTSDLC--QSMGDVATWCRALAEYARACAQAGRPLQGWRTQ 339
             P F ACHA+V P  +  +C +D C   S GD   +C A+A YA+AC + G  +  WRT 
Sbjct: 1100 GPTFAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCVS-WRTP 1158

Query: 340  LRQCTVHCK------EKAFTYNECIACCPASC-HPRASCVDSEIACVDGCY--CP-NGLI 389
               C + C       +  + Y  C   C  +C +PR  C+  ++  ++GCY  CP    I
Sbjct: 1159 -SICPLFCDYYNPEGQCEWHYQPCGVPCLRTCRNPRGDCL-RDVWGLEGCYPKCPPEAPI 1216

Query: 390  FEDGGCVAPAECP-------CEFHGTLYPPGSVVKED--CNTCTCTSGKWECSTAVCPAE 440
            F++      A CP       C  HG  Y PG+VV  D  C +C CT    EC+       
Sbjct: 1217 FDEDKMQCVATCPTPPLPPRCHVHGKSYRPGAVVPSDKNCQSCLCTERGVECTYKAEACV 1276

Query: 441  CSVT------GDIHFTTFDGRRYTFPATC 463
            C+        GD+ + T DG      A C
Sbjct: 1277 CTYNGQRFHPGDVIYHTTDGTGGCISARC 1305



 Score = 79.3 bits (194), Expect = 5e-14
 Identities = 69/285 (24%), Positives = 110/285 (38%), Gaps = 18/285 (6%)

Query: 2107 VTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASK 2166
            V I      V V+  PV  P S+ G  I+ +     +     + + W H   L++   +K
Sbjct: 143  VVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKVEARLGLVLMWNHDDSLLLELDTK 202

Query: 2167 TSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDS 2226
             +  +  GLCG  +G       L   + +     P  F +  ++             P  
Sbjct: 203  YAN-KTCGLCGDFNGMPVVSELLSHNTKL----TPMEFGNLQKMDDPTEQCQDPVPEPPR 257

Query: 2227 CATTDCSPCLRMVSNRTFSACHRFVPPESFCEL------WIRDTKYVQQPCVALTVYVAM 2280
              +T    C  ++  + FS C   V   S+ E       +  DT  +   C  L  Y   
Sbjct: 258  NCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLLSCVCHTLAEYSRQ 317

Query: 2281 C-HKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGC 2339
            C H   +  +WR  D+CP  C ++  Y  C + C    TC +        +HC     GC
Sbjct: 318  CTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCAD--TCSNQEHSRACEDHCVA---GC 372

Query: 2340 VCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGC 2384
             C EGT+L       C+P +KCAC  + G   A G T+++  + C
Sbjct: 373  FCPEGTVLDDIGQTGCVPVSKCACVYN-GAAYAPGATYSTDCTNC 416



 Score = 72.4 bits (176), Expect = 6e-12
 Identities = 78/332 (23%), Positives = 122/332 (36%), Gaps = 44/332 (13%)

Query: 2019 GLAVRVGGDRCC---PLWECA-----CRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPD 2070
            G  +RVG + C     +W C        C+++ D  ++TFDG   +   +  Y L Q+  
Sbjct: 875  GQTIRVGCNTCTCDSRMWRCTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNH- 933

Query: 2071 EMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPV--WPPVS 2128
                    D    +   +     C         A ++ +  F  K++     V       
Sbjct: 934  ----CGGKDSTQDSFRVVTENVPCGTTGTTCSKAIKIFLGGFELKLSHGKVEVIGTDESQ 989

Query: 2129 RYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLT 2188
               + I   G   ++ T   + + W   + + I   S   K +  GLCG  D  A ND  
Sbjct: 990  EVPYTIRQMGIYLVVDTDIGLVLLWDKKTSIFI-NLSPEFKGRVCGLCGNFDDIAVNDFA 1048

Query: 2189 LKDGSVVGGAEDPAPFLDSWQV----PSSLTSVGQTRFRP--DSCATTDCSPCLRMVSNR 2242
             +  SVVG   D   F +SW++    P +L         P   S A   CS    ++   
Sbjct: 1049 TRSRSVVG---DVLEFGNSWKLSPSCPDALAPKDPCTANPFRKSWAQKQCS----ILHGP 1101

Query: 2243 TFSACHRFVPPESFCELWIRDTKYVQQP------CVALTVYVAMCHKFHVCIEWRRSDYC 2296
            TF+ACH  V P  + E  + D             C A+  Y   CH+  +C+ WR    C
Sbjct: 1102 TFAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCVSWRTPSIC 1161

Query: 2297 PFLC-------SSDSTYQACVTACEPPKTCQD 2321
            P  C         +  YQ C   C   +TC++
Sbjct: 1162 PLFCDYYNPEGQCEWHYQPCGVPC--LRTCRN 1191



 Score = 70.1 bits (170), Expect = 3e-11
 Identities = 148/661 (22%), Positives = 225/661 (34%), Gaps = 108/661 (16%)

Query: 1977 TTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECA 2036
            T CVP+++  CV            N + + P       C     +   GG   C    C 
Sbjct: 386  TGCVPVSKCACV-----------YNGAAYAPGATYSTDCTNCTCS---GGRWSCQEVPCP 431

Query: 2037 CRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLV 2096
              CS+     F TFDG    +  +  Y+L++  D      + + +   L        CL 
Sbjct: 432  GTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCGLTD---SETCLK 488

Query: 2097 MLNMTHLAHQ-VTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPS---DIQIQ 2152
             + ++    Q V + + + +V ++      P+S     I      ++I   S    + +Q
Sbjct: 489  SVTLSLDGVQTVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQ 548

Query: 2153 WLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPS 2212
             + +  L +  A K  + Q  GLCG  +   A+D     G V   A   A F ++++  +
Sbjct: 549  LVPTMQLFMQLAPKL-RGQTCGLCGNFNSIQADDFRTLSGVVEATA---AAFFNTFKTQA 604

Query: 2213 SLTSVGQTRFRPDSCATTDCSPCLRMVSNRT-----FSACHRFVPPESFCELWIRDTKYV 2267
            +  ++  +   P S +  +        S  T     F  CH  V P ++    + DT   
Sbjct: 605  ACPNIRNSFEDPCSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNC 664

Query: 2268 QQP----CVALTVYVAMCHKFHVCIEWRRSDYCP---FLCSSDSTYQACVTACEPPKTCQ 2320
            ++     C AL+ YV  C    V +   R   C      C    TY   V+ C+P  TC+
Sbjct: 665  ERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVSTCQP--TCR 722

Query: 2321 DGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSS 2380
                G +      +  +GC+C +GT L    +  C+  + C C    G     GE+ + S
Sbjct: 723  SLSEGDITCSVGFIPVDGCICPKGTFLD--DTGKCVQASNCPCY-HRGSMIPNGESVHDS 779

Query: 2381 LSGC-CQH---QCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQ 2436
             + C C H    C       PV   C +P          V        P   G  C   Q
Sbjct: 780  GAICTCTHGKLSCIGGQAPAPV---CAAPM---------VFFDCRNATPGDTGAGC---Q 824

Query: 2437 TLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDS 2496
              C  L  TC                  YS +C         VP C     L+    G  
Sbjct: 825  KSCHTLDMTC------------------YSPQC---------VPGCVCPDGLVADGEG-G 856

Query: 2497 CCTSYFCACGDCPDSIPECQEGEALTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALV 2556
            C T+      DCP     C   EA      T  + C    C    +RC    C    A  
Sbjct: 857  CITA-----EDCP-----CVHNEASYRAGQTIRVGCNTCTCDSRMWRCTDDPC---LATC 903

Query: 2557 EVWSPDRCCPYK----SCECDCDTIPVPRCHLWEKSQLDEEFMHSVENV-CGCAKYECVK 2611
             V+       +     S   DC+   V   H   K    + F    ENV CG     C K
Sbjct: 904  AVYGDGHYLTFDGQSYSFNGDCEYTLVQN-HCGGKDSTQDSFRVVTENVPCGTTGTTCSK 962

Query: 2612 A 2612
            A
Sbjct: 963  A 963



 Score = 65.9 bits (159), Expect = 6e-10
 Identities = 106/450 (23%), Positives = 150/450 (33%), Gaps = 73/450 (16%)

Query: 1336 CEWRYDACASPCFQTCRDPRAASCRDVPRVEGCVPVC-PTPQVLDEVTQRCVYLEDCVEP 1394
            CEW Y  C  PC +TCR+PR    RDV  +EGC P C P   + DE   +CV    C  P
Sbjct: 1174 CEWHYQPCGVPCLRTCRNPRGDCLRDVWGLEGCYPKCPPEAPIFDEDKMQCV--ATCPTP 1231

Query: 1395 AVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTA 1454
             +       G    P   G   PSD+  Q                  + L T      T 
Sbjct: 1232 PLPPRCHVHGKSYRP---GAVVPSDKNCQ------------------SCLCTERGVECTY 1270

Query: 1455 TEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQ 1514
              E  V     Q      +    +    G   +      T      P +P +   P    
Sbjct: 1271 KAEACVCTYNGQRFHPGDVIYHTTDGTGGCISARCGANGTIERRVYPCSPTTPVPPTTFS 1330

Query: 1515 TPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRTTPL 1574
              TP +V  +  T         S   + +   PP+  +P      T  G       T+P 
Sbjct: 1331 FSTPPLVVSSTHTP--------SNGPSSAHTGPPSSAWP------TTAG-------TSPR 1369

Query: 1575 QPSLTASPSSRPVA------SPGAISRSP---TSSGSHKAV--LTPAVTKVISRTGVPQP 1623
                TAS S  PV       SP      P   T SG    +  L     +V      P+ 
Sbjct: 1370 TRLPTASASLPPVCGEKCLWSPWMDVSRPGRGTDSGDFDTLENLRAHGYRVCES---PRS 1426

Query: 1624 TQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQ---PMGSPASPQ 1680
             + ++  +P  PL   G   +  P   L  R+ E             Q   P+    S  
Sbjct: 1427 VECRAEDAPGVPLRALGQRVQCSPDVGLTCRNREQASGLCYNYQIRVQCCTPLA--CSTS 1484

Query: 1681 PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSG 1740
              P  + PP  ++ T       + P  TP   SLSTA      TP     ++      + 
Sbjct: 1485 SSPAQTTPPTTSKTTETRASGSSAPSSTPGTVSLSTA----RTTPAPGTATSVKKTFSTP 1540

Query: 1741 LPPDTSLPLAKVGTSAPVATPGPKASVITT 1770
             PP    P+    TS+ ++T  P  SV+++
Sbjct: 1541 SPP----PVPATSTSS-MSTTTPGTSVVSS 1565



 Score = 42.0 bits (97), Expect = 0.009
 Identities = 51/186 (27%), Positives = 71/186 (38%), Gaps = 33/186 (17%)

Query: 1451 PVTATEEPVVSPG--------PTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPH 1502
            PVT+T  PV +P         PTQ+T       T + +    T +P +    A      H
Sbjct: 1848 PVTST--PVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYA------H 1899

Query: 1503 TPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSS-RSPPAPRFPLMTKAVTV 1561
            T  ++S P A  T  P        TTR T   + SP  T S   + P+P     T +   
Sbjct: 1900 TTSTTSAPTARTTSAP--------TTRTT---SASPASTTSGPGNTPSPVPTTSTISAPT 1948

Query: 1562 RGHGSLPVRTTPLQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV- 1620
                S P  +T   P  T+S +S P  S  +   S T+S    +  +   T   S  G  
Sbjct: 1949 TSITSAPTTSTTSAP--TSSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPGTT 2006

Query: 1621 --PQPT 1624
              P PT
Sbjct: 2007 PSPVPT 2012



 Score = 41.6 bits (96), Expect = 0.011
 Identities = 55/200 (27%), Positives = 78/200 (39%), Gaps = 25/200 (12%)

Query: 1463 GPTQTTLQQPLELTASQLPAG--PTESPASKGVTASLLAIPHTPESSS--------LPVA 1512
            GP +  L   + +   + P G   T +P +   T S  AI  T  +SS        L   
Sbjct: 1826 GPFKMCLNYEVRVLCCETPRGCPVTSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTT 1885

Query: 1513 LQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLP--VR 1570
              T TP   +    TT  T     +P  T  + S P  R    + A T  G G+ P  V 
Sbjct: 1886 STTSTPQTSTTYAHTTSTT----SAP--TARTTSAPTTRTTSASPASTTSGPGNTPSPVP 1939

Query: 1571 TTPLQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSAS 1630
            TT    + T S +S P  S    + +PTSS +     +       S T  PQ +   + S
Sbjct: 1940 TTSTISAPTTSITSAPTTST---TSAPTSSTTSAPTTSTTSAPTSSTTSSPQTS---TTS 1993

Query: 1631 SPSTPLTVA-GTAAEQVPVS 1649
            +P+T  T   GT    VP +
Sbjct: 1994 APTTSTTSGPGTTPSPVPTT 2013



 Score = 41.6 bits (96), Expect = 0.011
 Identities = 51/195 (26%), Positives = 72/195 (36%), Gaps = 31/195 (15%)

Query: 1572 TPLQPSLTASPSSRPVASPG-AISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSAS 1630
            TP    +T++P + P    G AIS + ++S   K+  T  VT   + T     T A + S
Sbjct: 1843 TPRGCPVTSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTS 1902

Query: 1631 SPSTPL--TVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAP 1688
            + S P   T +         SP +T S                  G   +P P P  S  
Sbjct: 1903 TTSAPTARTTSAPTTRTTSASPASTTS------------------GPGNTPSPVPTTSTI 1944

Query: 1689 PRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLP 1748
              P   TT  T +P     T A  S +T+    + T   +  +T   Q  +   P TS  
Sbjct: 1945 SAP---TTSITSAPTTST-TSAPTSSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTST- 1999

Query: 1749 LAKVGTSAPVATPGP 1763
                 TS P  TP P
Sbjct: 2000 -----TSGPGTTPSP 2009



 Score = 41.2 bits (95), Expect = 0.015
 Identities = 82/359 (22%), Positives = 122/359 (33%), Gaps = 53/359 (14%)

Query: 1450 PPVTATEEPVVSP--GPTQTTLQQPLELTASQLPA-----GPTESPASKGV-TASLLAIP 1501
            P   AT  P   P    TQTT    +   +++ P      GPT +  ++G  T  +    
Sbjct: 1684 PKTVATTRPTPHPTGAQTQTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPVTRNC 1743

Query: 1502 HTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTV 1561
            H   + +    +  P+PG   G  ET    +I +G     +  R     R     K+   
Sbjct: 1744 HPRCTWTKWFDVDFPSPGPHGGDKETYN-NIIRSGEK---ICRRPEEITRLQCRAKS--- 1796

Query: 1562 RGHGSLPVRTTPLQPSLTASPSSRPVA---SPGAISRSPTSSGSHKAVLTPAVTKVISRT 1618
                          P ++     + V      G + R+    G  K  L   V  +   T
Sbjct: 1797 -------------HPEVSIEHLGQVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCET 1843

Query: 1619 GVPQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPAS 1678
                P  +   ++PSTP   A  +  Q   S   +R+  +V ++       S       S
Sbjct: 1844 PRGCPVTSTPVTAPSTPSGRA-ISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTS 1902

Query: 1679 PQPHPLPSAPPRPAQHTTMATRSPA--------LPPETPAAASLSTATDGLAATPFMSLE 1730
                P       P   TT A  SPA         P   P  +++S  T  + + P  S  
Sbjct: 1903 TTSAPTARTTSAPTTRTTSA--SPASTTSGPGNTPSPVPTTSTISAPTTSITSAPTTSTT 1960

Query: 1731 STRPSQLLSGLPPDTSLPLAKVGTSAPVA--TPGPKASVITTPLQPQATTLPAQTLSPV 1787
            S   S   S   P TS       TSAP +  T  P+ S  + P     T+ P  T SPV
Sbjct: 1961 SAPTSSTTSA--PTTST------TSAPTSSTTSSPQTSTTSAP-TTSTTSGPGTTPSPV 2010



 Score = 40.8 bits (94), Expect = 0.019
 Identities = 40/171 (23%), Positives = 64/171 (37%), Gaps = 19/171 (11%)

Query: 1672 PMGSPASPQPHPLPSAPP-------------RPAQHTTMATRSPALPPETPAAASLSTAT 1718
            P G P +  P   PS P              + ++ TT+ T S    P+T    + +T+T
Sbjct: 1844 PRGCPVTSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTST 1903

Query: 1719 DGLAATPFMSLESTR-----PSQLLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTPLQ 1773
                     S  +TR     P+   SG P +T  P+    T +   T    A   +T   
Sbjct: 1904 TSAPTARTTSAPTTRTTSASPASTTSG-PGNTPSPVPTTSTISAPTTSITSAPTTSTTSA 1962

Query: 1774 PQATTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTS 1824
            P ++T  A T S     T +  +     T  AP  + T+      + +PT+
Sbjct: 1963 PTSSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPGTTPSPVPTT 2013



 Score = 39.3 bits (90), Expect = 0.056
 Identities = 47/167 (28%), Positives = 64/167 (38%), Gaps = 21/167 (12%)

Query: 1754 TSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPA----AMTQAHPPTHIAPPAA 1809
            TS PV  P   +    +P Q  ++   ++T + V   T +    + T AH  +  + P A
Sbjct: 1850 TSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTA 1909

Query: 1810 GT--APGLLLGATLPTS-----GVLPVAEGTASMVSV-------VPRKSTTGKVAILSKQ 1855
             T  AP     +  P S     G  P    T S +S         P  STT   A  S  
Sbjct: 1910 RTTSAPTTRTTSASPASTTSGPGNTPSPVPTTSTISAPTTSITSAPTTSTTS--APTSST 1967

Query: 1856 VSLPTSMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTS 1902
             S PT+   SA    T  +P TS    P  +   G    T  PVPT+
Sbjct: 1968 TSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSG-PGTTPSPVPTT 2013



 Score = 35.8 bits (81), Expect = 0.62
 Identities = 43/169 (25%), Positives = 59/169 (34%), Gaps = 13/169 (7%)

Query: 1407 TLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQ 1466
            T P +      S  +   S +  RT T     T + P T+      T+T     +  PT 
Sbjct: 1855 TAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTST-----TSAPTA 1909

Query: 1467 TTLQQPLELTASQLPAGPTESPA---SKGVTASLLAIPHTPESSSLPVALQTPTPGMVSG 1523
             T   P   T S  PA  T  P    S   T S ++ P T   +S P    T  P   + 
Sbjct: 1910 RTTSAPTTRTTSASPASTTSGPGNTPSPVPTTSTISAP-TTSITSAPTTSTTSAPTSSTT 1968

Query: 1524 AMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRTT 1572
            +  TT  T     S   +  + +  AP     T   +  G    PV TT
Sbjct: 1969 SAPTTSTTSAPTSSTTSSPQTSTTSAP----TTSTTSGPGTTPSPVPTT 2013



 Score = 34.7 bits (78), Expect = 1.4
 Identities = 19/54 (35%), Positives = 26/54 (48%), Gaps = 3/54 (5%)

Query: 1339 RYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCPTPQVLDEVTQR-CVYLEDC 1391
            +Y  C SPC  TC +   +   +   V GC   CP   VLD++ Q  CV +  C
Sbjct: 343  QYHECRSPCADTCSNQEHSRACEDHCVAGC--FCPEGTVLDDIGQTGCVPVSKC 394



 Score = 32.7 bits (73), Expect = 5.3
 Identities = 29/96 (30%), Positives = 40/96 (41%), Gaps = 7/96 (7%)

Query: 1724 TPFMSLESTRPSQLLSGLPPDTS--LPLAKVGTSAPVATPGPKA--SVITTPLQPQATTL 1779
            TP     S+ P+Q     PP TS        G+SAP +TPG  +  +  TTP    AT++
Sbjct: 1477 TPLACSTSSSPAQTT---PPTTSKTTETRASGSSAPSSTPGTVSLSTARTTPAPGTATSV 1533

Query: 1780 PAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGL 1815
                 +P  P  PA  T +   T        + P L
Sbjct: 1534 KKTFSTPSPPPVPATSTSSMSTTTPGTSVVSSKPTL 1569


>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
          Length = 5765

 Score =  574 bits (1479), Expect = e-163
 Identities = 348/1128 (30%), Positives = 539/1128 (47%), Gaps = 72/1128 (6%)

Query: 78   ICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAV 137
            +C  WG  H +TFDG  +   G  +Y          + F++Q+      GS P      V
Sbjct: 76   VCSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCRAAYEDFNVQLRRG-LVGSRP-----VV 129

Query: 138  SLFFVGEQEIHLAKE---VTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGAS 194
            +   +  Q + L      V   G R +LP+      ++Q   Y+ V  +   T  W+G  
Sbjct: 130  TRVVIKAQGLVLEASNGSVLINGQREELPYSRTGLLVEQSGDYIKVSIRLVLTFLWNGED 189

Query: 195  AVYIKMSPELLGWTHGLCGNNNADPK-DDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPT 253
            +  +++ P+    T GLCG+ N  P  ++    + +LT   ++F +  +   P +   P 
Sbjct: 190  SALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLTP--LQFGNLQKLDGPTEQC-PD 246

Query: 254  TSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVA 313
               LP   C  +     +G+  +   LL P F  CHA V    + A+C  DLC+      
Sbjct: 247  PLPLPAGNCTDE-----EGICHR--TLLGPAFAECHALVDSTAYLAACAQDLCRCP---T 296

Query: 314  TWCRALAEYARACAQAGRPLQGWRTQL---RQCTVHCKEKAFTYNECIACCPASCHPRAS 370
              C    EY+R CA AG   + WR      R C ++ +     + EC + C  +C     
Sbjct: 297  CPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQ-----HQECGSPCTDTCSNPQR 351

Query: 371  CVDSEIACVDGCYCPNG---LIFED---GGCVAPAECPCEFHGTLYPPGSVVKEDCNTCT 424
                E  CVDGC+CP G    + +D    GC+   +CPC   G  Y PG+     C++CT
Sbjct: 352  AQLCEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHGGRTYSPGTSFNTTCSSCT 411

Query: 425  CTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAP 484
            C+ G W+C    CP  CSV G  H +T+D + Y     C Y+L+K  +  +FTV  +   
Sbjct: 412  CSGGLWQCQDLPCPGTCSVQGGAHISTYDEKLYDLHGDCSYVLSKKCADSSFTVLAELRK 471

Query: 485  CGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFL 544
            CGL  +  C+++V++ L       + +   G V L   Y  +P    +   +   SS F+
Sbjct: 472  CGLTDNENCLKAVTLSLDGGDTA-IRVQADGGVFLNSIYTQLPLSAAN-ITLFTPSSFFI 529

Query: 545  RVRTNVGVRVLYDREGL-RLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQL 603
             V+T +G+++L     L ++++++D        GLCG FN N  DDF +  GV E+T   
Sbjct: 530  VVQTGLGLQLLVQLVPLMQVFVRLDPAHQGQMCGLCGNFNQNQADDFTALSGVVEATGAA 589

Query: 604  FGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLT--GEMFAPCSAFLSPVPYF 661
            F N+WK  +AC+     S  DPC + ++  +Y+   CS LT     F+ C + ++P P+ 
Sbjct: 590  FANTWKAQAACAN-ARNSFEDPCSLSVENENYARHWCSRLTDPNSAFSRCHSIINPKPFH 648

Query: 662  EQCRRDACRC--GQPCLCATLAHYAHLCRRHGLPV-DFRARLPACAL-SCEASKEYSPCV 717
              C  D C C   + CLCA L+ Y H C   G+ + D+R  +    + +C  S+ Y+  V
Sbjct: 649  SNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLSDWRDGVCTKYMQNCPKSQRYAYVV 708

Query: 718  APCGRTCQDLASPEA-CGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQ 776
              C  TC+ L+  +  C V           V+GC CP  T+L+  A  CVP  +C C+  
Sbjct: 709  DACQPTCRGLSEADVTCSVSFVP-------VDGCTCPAGTFLN-DAGACVPAQECPCYAH 760

Query: 777  GVDYPPGDSDIPSLGHCHCKDGVMSC--DSRAPAAACPAGQVFVNCSDLHTDLELSRERT 834
            G    PG+        C C  G +SC   S   +  C A  V+++CS+       +    
Sbjct: 761  GTVLAPGEVVHDEGAVCSCTGGKLSCLGASLQKSTGCAAPMVYLDCSNSSAGTPGAE--- 817

Query: 835  CEQQLLNLSVSARGP-CLSGCACPQGLLRHGDA-CFLPEECPCTWKGKEYFPGDQVMSPC 892
            C +    L V      C+SGC CP GL+  G   C   E+CPC      Y PG+ +   C
Sbjct: 818  CLRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKPGETIRVDC 877

Query: 893  HTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVK-----STSDVS 947
            +TC C+   ++C+   C  TC AYGD H+ TFDG  + F G+C+  L +     +T+  +
Sbjct: 878  NTCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNTTHGT 937

Query: 948  FSVIVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFT 1007
            F ++ EN+ C ++G  C K I + V +  ++  + +          D      + +G F 
Sbjct: 938  FRIVTENIPCGTTGTTCSKAIKLFVESYELILQEGTFKAVARGPGGDPPYKIRY-MGIFL 996

Query: 1008 LVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEF 1067
            ++      + + WD++T+V ++    ++G++ GLCGNFD   IN+  T     + +  EF
Sbjct: 997  VIE--THGMAVSWDRKTSVFIRLHQDYKGRVCGLCGNFDDNAINDFATRSRSVVGDALEF 1054

Query: 1068 GSSWA-AVECPDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLT 1126
            G+SW  +  CPD L P+D C  NP R+ +A+K+CSIL    F  C   VD T +Y  C+ 
Sbjct: 1055 GNSWKLSPSCPDALAPKDPCTANPFRKSWAQKQCSILHGPTFAACRSQVDSTKYYEACVN 1114

Query: 1127 DTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFN 1174
            D C C  GGDCECFC +V+AYA  C   G+ V WRTP  CP  CDF+N
Sbjct: 1115 DACACDSGGDCECFCTAVAAYAQACHDAGLCVSWRTPDTCPLFCDFYN 1162



 Score =  237 bits (605), Expect = 1e-61
 Identities = 152/481 (31%), Positives = 221/481 (45%), Gaps = 64/481 (13%)

Query: 361  CPASCHPR-ASCVDSEIACVDGCYCPNGLIFE-DGGCVAPAECPCEFHGTLYPPGSVVKE 418
            C  SCH     C  +   CV GC CP GL+ +  GGC+A  +CPC  +   Y PG  ++ 
Sbjct: 818  CLRSCHTLDVGCFSTH--CVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKPGETIRV 875

Query: 419  DCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAK-----SRSS 473
            DCNTCTC + +WECS  +C   C   GD HF TFDG RY+F  +C+YILA+     + + 
Sbjct: 876  DCNTCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNTTH 935

Query: 474  GTFTVTLQNAPCGLNQDGAC------VQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIP 527
            GTF +  +N PCG             V+S  +IL +   + V     GD          P
Sbjct: 936  GTFRIVTENIPCGTTGTTCSKAIKLFVESYELILQEGTFKAVARGPGGD----------P 985

Query: 528  PYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQ 587
            PY        R   +FL + T+ G+ V +DR+   +++++ Q +     GLCG F+ N  
Sbjct: 986  PYKI------RYMGIFLVIETH-GMAVSWDRK-TSVFIRLHQDYKGRVCGLCGNFDDNAI 1037

Query: 588  DDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEM 647
            +DF +           FGNSWK   +C   ++  P DPC  +    S++ + CS+L G  
Sbjct: 1038 NDFATRSRSVVGDALEFGNSWKLSPSCPDALA--PKDPCTANPFRKSWAQKQCSILHGPT 1095

Query: 648  FAPCSAFLSPVPYFEQCRRDACRCGQ----PCLCATLAHYAHLCRRHGLPVDFRARLPAC 703
            FA C + +    Y+E C  DAC C       C C  +A YA  C   GL V +R     C
Sbjct: 1096 FAACRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACHDAGLCVSWRTP-DTC 1154

Query: 704  ALSCE-------ASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGC--ACPP 754
             L C+           Y PC APC +TC++ +      + G         +EGC   CPP
Sbjct: 1155 PLFCDFYNPHGGCEWHYQPCGAPCLKTCRNPSGHCLVDLPG---------LEGCYPKCPP 1205

Query: 755  -DTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGH---CHCKDGVMSCDSRAPAAA 810
               + +     CV   QC C+ +  +Y    + +P+  +   C+C    + C     A  
Sbjct: 1206 SQPFFNEDQMKCVA--QCGCYDKDGNYYDVGARVPTAENCQSCNCTPSGIQCAHSLEACT 1263

Query: 811  C 811
            C
Sbjct: 1264 C 1264



 Score =  207 bits (528), Expect = 9e-53
 Identities = 320/1341 (23%), Positives = 466/1341 (34%), Gaps = 245/1341 (18%)

Query: 1401 EALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVV 1460
            E     T+  ++   T +         +P T      LT AA  T A  P  T    P  
Sbjct: 4361 ETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATGPTAT----PSS 4416

Query: 1461 SPGPTQ--TTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQTPTP 1518
            +PG T   T L      TAS    G T +P+S   T  +L  P T  + ++P    T T 
Sbjct: 4417 TPGTTWILTELTTTATTTAS---TGSTATPSSTPGTTWILTEPSTTATVTVPTG-STATA 4472

Query: 1519 GMVSGAMETTRVTVIFAGSPNITVSSRSPP-----APRFPLMTKAVTVRGHGS------- 1566
                    T  V+   A +P +T S  +P      A   P +    T     S       
Sbjct: 4473 SSTQATAGTPHVSTT-ATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSFTAIPSS 4531

Query: 1567 --------LPVRTTPLQPSLTASPSSRP--VASPGAISRSPTSSGSHKAVLTPAVTKVIS 1616
                    L   TTP     TA+PSS P  V +   ++ + T++G+  +V TP+ T   +
Sbjct: 4532 SLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTATATTTGATGSVATPSSTPGTA 4591

Query: 1617 RTG-VPQPTQ----AQSASSPSTPLTV-AGTAAEQVPVSPLATRSLEIVLSTEKGEAGHS 1670
             T  VP  T     A  +SSP T LT     +    P +   T S   V  +      H+
Sbjct: 4592 HTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTTTPTTSGSTVTPSSIPGTTHT 4651

Query: 1671 QPM----------GSPASPQPHPLPSAPPRPAQHTTM----ATRSPALPPETPAAASLST 1716
              +          GS A+P      S  P P+  TT     AT S   P  TP    ++ 
Sbjct: 4652 ARVLTTTTTTVATGSMATPSSSTQTSGTP-PSLTTTATTITATGSTTNPSSTPGTTPITP 4710

Query: 1717 ATDGLAATPFMSLESTRPS---QLLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTPLQ 1773
                 A TP  +      S   +  + LP  TS       TS    TP P +++ TT   
Sbjct: 4711 VLTSTATTPAATSSKATSSSSPRTATTLPVLTSTATKSTATSF---TPIPSSTLWTTWTV 4767

Query: 1774 PQATTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGT-------APGLLLGATLPTSGV 1826
            P  TT P  T+S +   T +     H  T +   A  T        P   LG T   + +
Sbjct: 4768 PAQTTTPMSTMSTI--HTSSTPETTHTSTVLTTTATMTRATNSTATPSSTLGTTRILTEL 4825

Query: 1827 LPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGSAEGGPTELTPATSH------- 1879
               A  TA+  S     ST G   IL++  ++ T M  +        T  T+H       
Sbjct: 4826 TTTATTTAATGSTATLSSTPGTTWILTEPSTIATVMVPTGSTATASSTLGTAHTPKVVTT 4885

Query: 1880 ----PLTPLVAEPEGAQAGTA-LPVPTSYALSRVSARTAPQDSMLVLLPQ---------- 1924
                P       P  +  GT   P     +L   S  T     +  L P           
Sbjct: 4886 MATMPTATASTVPSSSTVGTTRTPAVLPSSLPTFSVSTVSSSVLTTLRPTGFPSSHFSTP 4945

Query: 1925 -LAEAHGTSAGP-HLAAEPVDEA----------------------TTEPSGRSAPALSIV 1960
                A G    P  +     D A                      T+ P   SAP     
Sbjct: 4946 CFCRAFGQFFSPGEVIYNKTDRAGCHFYAVCNQHCDIDRFQGACPTSPPPVSSAP----- 5000

Query: 1961 EGLAEALATTTEANTSTTCVPIAE-------QDCVRHICL-EGQLIRVNQSQHCPQGAAP 2012
                  L++ + A      +P+ +       ++C    C+ + +++ ++     P+  A 
Sbjct: 5001 ------LSSPSPAPGCDNAIPLRQVNETWTLENCTVARCVGDNRVVLLD-----PKPVAN 5049

Query: 2013 PRCGILGLAVRVG--GDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPD 2070
              C    L ++V      C   +EC C CS++    + TFDG+         Y+L +   
Sbjct: 5050 VTCVNKHLPIKVSDPSQPCDFHYECECICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIH 5109

Query: 2071 EM---LTVHVLD---CKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVW 2124
                 L++++ +     SA       P    +      +   VT+     +  +    + 
Sbjct: 5110 ARFGNLSLYLDNHYCTASATAAAARCPRALSIHYKSMDIVLTVTMVHGKEEGLILFDQI- 5168

Query: 2125 PPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQ---------GHGL 2175
             PVS  GF     G +  +L  + +++  + + G+ +    +  +A+           G 
Sbjct: 5169 -PVSS-GF--SKNGVLVSVLGTTTMRVD-IPALGVSVTFNGQVFQARLPYSLFHNNTEGQ 5223

Query: 2176 CGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSC-------- 2227
            CG C  +  +D   +DG+     +D A    +W VP S         R D C        
Sbjct: 5224 CGTCTNNQRDDCLQRDGTTAASCKDMAK---TWLVPDS---------RKDGCWAPTGTPP 5271

Query: 2228 ------------ATTDCSP---CLRMVSNRTFSACHRFVPPESFCELWIRD--TKYVQQP 2270
                          T C P   C  M+S + F+ CH  VPP  F    I D     ++ P
Sbjct: 5272 TASPAAPVSSTPTPTPCPPQPLCDLMLS-QVFAECHNLVPPGPFFNACISDHCRGRLEVP 5330

Query: 2271 CVALTVYVAMCHKFHVCIEWRRSD--YCPFLCSSDSTYQACVTACEPPKTCQDGILGPLD 2328
            C +L  Y  +C    VC +WR +    C   C     Y+ C      P TC      P  
Sbjct: 5331 CQSLEAYAELCRARGVCSDWRGATGGLCDLTCPPTKVYKPCGPI--QPATCNSRNQSP-- 5386

Query: 2329 PEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQ 2388
                + + EGC C E  IL   H  +C+    C C    G P+  GE W S+   C   +
Sbjct: 5387 --QLEGMAEGCFCPEDQILFNAHMGICVQA--CPCVGPDGFPKFPGERWVSNCQSCVCDE 5442

Query: 2389 CQAPDTIVPVDLGCPSPRPESCLRFGEVALLLP-TKDPCCLGTVCVCNQTLCEGLAPTCR 2447
                    P+       +P  C R G V +  P  ++PCC  TVCVCN T C    P C 
Sbjct: 5443 GSVSVQCKPLPCDAQG-QPPPCNRPGFVTVTRPRAENPCCPETVCVCNTTTCPQSLPVCP 5501

Query: 2448 PGHRLLTHFQEDSCCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGD 2507
            PG   +   +E  CCP++ C   P LC      +         G L    CT   C  GD
Sbjct: 5502 PGQESICTQEEGDCCPTFRCR--PQLCSYN--GTFYGVGATFPGALPCHMCT---CLSGD 5554

Query: 2508 CPDSIPECQEGEALTVHRNTTELCCP--------LYQCVCENFRCPQVQC----GLGTAL 2555
              D   +CQE        NTT   CP          QC  E   C Q  C    G    L
Sbjct: 5555 TQDPTVQCQEDAC----NNTT---CPQGFEYKRVAGQCCGE---CVQTACLTPDGQPVQL 5604

Query: 2556 VEVW---SPDRCCPYKSCECD 2573
             E W     D C  Y  CE +
Sbjct: 5605 NETWVNSHVDNCTVY-LCEAE 5624



 Score =  137 bits (344), Expect = 2e-31
 Identities = 116/411 (28%), Positives = 177/411 (43%), Gaps = 42/411 (10%)

Query: 79   CRAWGQHHVETFDGLYYYLSGKGSYTLV----GRHEPEGQSFSIQVHNDPQCGSSPYTCS 134
            C A+G  H  TFDG  Y   G   Y L     G +   G +F I   N P CG++  TCS
Sbjct: 898  CVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNTTHG-TFRIVTENIP-CGTTGTTCS 955

Query: 135  RAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQ-QLAGYVIVRHQSAFTLAWDGA 193
            +A+ LF    + I     +  G  +       G    + +  G  +V       ++WD  
Sbjct: 956  KAIKLFVESYELI-----LQEGTFKAVARGPGGDPPYKIRYMGIFLVIETHGMAVSWDRK 1010

Query: 194  SAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPT 253
            ++V+I++  +  G   GLCGN + +  +D  T S  +  D +EF +SW+       P   
Sbjct: 1011 TSVFIRLHQDYKGRVCGLCGNFDDNAINDFATRSRSVVGDALEFGNSWKLS-----PSCP 1065

Query: 254  TSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLC--QSMGD 311
             +  P+ PC   NP       +QC  L  P F AC + V    +  +C +D C   S GD
Sbjct: 1066 DALAPKDPCTA-NPFRKSWAQKQCSILHGPTFAACRSQVDSTKYYEACVNDACACDSGGD 1124

Query: 312  VATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEK------AFTYNECIACCPASC 365
               +C A+A YA+AC  AG  +  WRT    C + C          + Y  C A C  +C
Sbjct: 1125 CECFCTAVAAYAQACHDAGLCVS-WRTP-DTCPLFCDFYNPHGGCEWHYQPCGAPCLKTC 1182

Query: 366  -HPRASCVDSEIACVDGCY--CPNGL-IFEDGGCVAPAECPC-EFHGTLYPPGSVVK--E 418
             +P   C+  ++  ++GCY  CP     F +      A+C C +  G  Y  G+ V   E
Sbjct: 1183 RNPSGHCL-VDLPGLEGCYPKCPPSQPFFNEDQMKCVAQCGCYDKDGNYYDVGARVPTAE 1241

Query: 419  DCNTCTCTSGKWECSTAVCPAECSVTG------DIHFTTFDGRRYTFPATC 463
            +C +C CT    +C+ ++    C+         D+ + T DG      A C
Sbjct: 1242 NCQSCNCTPSGIQCAHSLEACTCTYEDRTYSYQDVIYNTTDGLGACLIAIC 1292



 Score =  132 bits (333), Expect = 4e-30
 Identities = 139/540 (25%), Positives = 208/540 (38%), Gaps = 87/540 (16%)

Query: 437  CPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSS--GTFTVTLQNAPCGLNQDGA-- 492
            C   CS+ G  H++TFDG  YTF   C Y+L +   +  G  ++ L N  C  +   A  
Sbjct: 5074 CECICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTASATAAAA 5133

Query: 493  -CVQSVSV-ILHQDPRRQVTLTQAGD--VLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRT 548
             C +++S+     D    VT+    +  ++LFDQ  +   ++ +   +  L +  +RV  
Sbjct: 5134 RCPRALSIHYKSMDIVLTVTMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMRVDI 5193

Query: 549  N-VGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNS 607
              +GV V ++ +  +  L     +  +T G CGT   N +DD L   G   ++ +    +
Sbjct: 5194 PALGVSVTFNGQVFQARLPYSL-FHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKT 5252

Query: 608  W-----------------KTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAP 650
            W                  T S  +P+ S     PC             C ++  ++FA 
Sbjct: 5253 WLVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQ--------PLCDLMLSQVFAE 5304

Query: 651  CSAFLSPVPYFEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFR-ARLPACALSCEA 709
            C   + P P+F  C  D CR      C +L  YA LCR  G+  D+R A    C L+C  
Sbjct: 5305 CHNLVPPGPFFNACISDHCRGRLEVPCQSLEAYAELCRARGVCSDWRGATGGLCDLTCPP 5364

Query: 710  SKEYSPCVAPCGRTCQDL-ASPEACGVDGGDDLSRDECVEGCACPPDTYL-DTQADLCVP 767
            +K Y PC      TC     SP+  G+            EGC CP D  L +    +CV 
Sbjct: 5365 TKVYKPCGPIQPATCNSRNQSPQLEGM-----------AEGCFCPEDQILFNAHMGICV- 5412

Query: 768  RNQCSC-HFQGVDYPPGDSDIPSLGHCHCKDGVMS-------CDSRAPAAACPAGQVFVN 819
               C C    G    PG+  + +   C C +G +S       CD++     C       N
Sbjct: 5413 -QACPCVGPDGFPKFPGERWVSNCQSCVCDEGSVSVQCKPLPCDAQGQPPPC-------N 5464

Query: 820  CSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQG-----LLRHGDAC--FLPEE 872
                 T      E  C  + + +  +   P  S   CP G         GD C  F    
Sbjct: 5465 RPGFVTVTRPRAENPCCPETVCVCNTTTCP-QSLPVCPPGQESICTQEEGDCCPTFRCRP 5523

Query: 873  CPCTWKGKEY-----FPGDQVMSPCHTCVCQRG-----SFQCTLHPCASTCTAYGDRHYR 922
              C++ G  Y     FPG     PCH C C  G     + QC    C +T    G  + R
Sbjct: 5524 QLCSYNGTFYGVGATFPG---ALPCHMCTCLSGDTQDPTVQCQEDACNNTTCPQGFEYKR 5580



 Score = 93.2 bits (230), Expect = 3e-18
 Identities = 153/618 (24%), Positives = 226/618 (36%), Gaps = 98/618 (15%)

Query: 1398 VPTEALGNETLPPSQGL------PTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPP 1451
            +P+   G  T PP + L      PT +  +   S  SPRT T  P LT  A  +TA    
Sbjct: 3014 IPSSTPG--TAPPPKVLTSTATTPTATSSKAT-SSSSPRTATTLPVLTSTATKSTA---- 3066

Query: 1452 VTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPV 1511
             + T  P  + G T T  +Q     A+     P+ +P +   T+++L    T   ++  +
Sbjct: 3067 TSFTPIPSFTLGTTGTLPEQTTTPMATMSTIHPSSTPETTH-TSTVLTTKATTTRATSSM 3125

Query: 1512 ALQTPTPGMVSGAME-TTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPVR 1570
            +  + TPG      E TT  T   A  P  T SS        P  T  +T          
Sbjct: 3126 STPSSTPGTTWILTELTTAATTTAATGPTATPSST-------PGTTWILT---------- 3168

Query: 1571 TTPLQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVT-KVISRTGVPQPTQAQSA 1629
                +PS TA+ +  P  S    S +  ++G+ K + + A T  VIS    P  +   + 
Sbjct: 3169 ----EPSTTATVTV-PTGSTATASSTRATAGTLKVLTSTATTPTVISSRATPSSSPGTAT 3223

Query: 1630 SSP---STPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPS 1686
            + P   ST  T   T+   +P S L T    +  +T       +    +P+S       S
Sbjct: 3224 ALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTPTA---TMSTATPSSTPETVHTS 3280

Query: 1687 APPRPAQHTTMATRSPALPPETPAAASL----STATDGLAATPFMSLESTRPSQLLSGLP 1742
                    TT AT S A P  TP  A      +T T G  ATP     S+ P   L+  P
Sbjct: 3281 TVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTATP-----SSSPGTALT--P 3333

Query: 1743 P----DTSLPLAKVGTSAPVATPGP--KASVITTPLQPQATTLPAQTLSPVLPFTPAAMT 1796
            P     T+ P  +  T  P + PG    A+V+TT     AT   A         TP++ T
Sbjct: 3334 PVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMA---------TPSSST 3384

Query: 1797 QAHPPTHIAPPAAGTAPGLLLGA-TLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQ 1855
            Q           +GT P L   A T+  +G       T     + P  +TT      +  
Sbjct: 3385 Q----------TSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSS 3434

Query: 1856 VSLPTSMYGSAEGGPTELTPATSH-----PLTP------LVAEPEGAQAGTALPVPTSYA 1904
               P+S  G+    P   T AT+H     P +P        +   G    T +  P++  
Sbjct: 3435 TVTPSSALGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVT 3494

Query: 1905 LSRVSARTAPQDSMLVLLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLA 1964
                +A T+         P L+  H +S        P    TT P      + +      
Sbjct: 3495 SHTPAATTSTTQHS---TPALSSPHPSS---RTTESPPSPGTTTPGHTRGTSRTTATATP 3548

Query: 1965 EALATTTEANTSTTCVPI 1982
                T+T   +S T  PI
Sbjct: 3549 SKTRTSTLLPSSPTSAPI 3566



 Score = 92.8 bits (229), Expect = 4e-18
 Identities = 102/400 (25%), Positives = 149/400 (37%), Gaps = 48/400 (12%)

Query: 74   ERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYT- 132
            E + IC  WG  H  TFDG  Y   G  +Y L+        + S+ + N     S+    
Sbjct: 5073 ECECICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTASATAAA 5132

Query: 133  --CSRAVSLFFVGEQEIHLAKEVTHG---GMRV--QLPHVMGSAR---LQQLAGYVIVRH 182
              C RA+S+ +    +I L   + HG   G+ +  Q+P   G ++   L  + G   +R 
Sbjct: 5133 ARCPRALSIHYKS-MDIVLTVTMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMRV 5191

Query: 183  Q-SAFTLAWDGASAVYIKMSPELL--GWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVH 239
               A  ++      V+    P  L    T G CG    + +DD +   G       +   
Sbjct: 5192 DIPALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAK 5251

Query: 240  SW-------------QEQAPNQPPGPTTSSLPRP-PCLQQNPGTMQGVYEQCEALLRPPF 285
            +W                 P   P    SS P P PC  Q           C+ +L   F
Sbjct: 5252 TWLVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQ---------PLCDLMLSQVF 5302

Query: 286  DACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQL-RQCT 344
              CH  V P PF  +C SD C+  G +   C++L  YA  C   G     WR      C 
Sbjct: 5303 AECHNLVPPGPFFNACISDHCR--GRLEVPCQSLEAYAELCRARG-VCSDWRGATGGLCD 5359

Query: 345  VHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCP-NGLIFEDGGCVAPAECPC 403
            + C      Y  C    PA+C+ R      E    +GC+CP + ++F     +    CPC
Sbjct: 5360 LTCPPTK-VYKPCGPIQPATCNSRNQSPQLE-GMAEGCFCPEDQILFNAHMGICVQACPC 5417

Query: 404  EF-HGTLYPPGSVVKEDCNTCTCTSG--KWECSTAVCPAE 440
                G    PG     +C +C C  G    +C    C A+
Sbjct: 5418 VGPDGFPKFPGERWVSNCQSCVCDEGSVSVQCKPLPCDAQ 5457



 Score = 89.0 bits (219), Expect = 6e-17
 Identities = 96/386 (24%), Positives = 149/386 (38%), Gaps = 60/386 (15%)

Query: 2482 CRQDQILITGRLGDSCCTSYFCACGDCPDSIPE------CQEGEALTVHRNTTELCCPLY 2535
            C +DQIL    +G   C    C C   PD  P+          ++      +  + C   
Sbjct: 5397 CPEDQILFNAHMG--ICVQA-CPCVG-PDGFPKFPGERWVSNCQSCVCDEGSVSVQCKPL 5452

Query: 2536 QCVCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIP--VPRCHLWEKSQLDEE 2593
             C  +    P  + G  T +    + + CCP   C C+  T P  +P C   ++S   +E
Sbjct: 5453 PCDAQGQPPPCNRPGFVT-VTRPRAENPCCPETVCVCNTTTCPQSLPVCPPGQESICTQE 5511

Query: 2594 FMHSVENVCGCAKYECVKAPVCLSR----ELGVMQPGQTVVELSADGVCHTSRCTT--VL 2647
                 E  C C  + C +  +C        +G   PG           CH   C +    
Sbjct: 5512 -----EGDC-CPTFRC-RPQLCSYNGTFYGVGATFPGAL--------PCHMCTCLSGDTQ 5556

Query: 2648 DPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTTSLFLPGA 2707
            DP     +    +  C       Q +E+ R    CCG C   +CL   P+G         
Sbjct: 5557 DPTVQCQEDACNNTTCP------QGFEYKRVAGQCCGECVQTACL--TPDGQPVQL--NE 5606

Query: 2708 SW----IADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTCKED 2763
            +W    + +C  + C +     +L   P SCP ++        GS+  +  GCC +C+ED
Sbjct: 5607 TWVNSHVDNCTVYLCEAEGGVHLLTPQPASCPDVSSCR-----GSLRKT--GCCYSCEED 5659

Query: 2764 GRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVGLQR 2823
              SC +V I  TI  ++    T VN+  C+G CP AS Y+         C CC+E  +  
Sbjct: 5660 --SC-QVRINTTILWHQ-GCETEVNITFCEGSCPGASKYSAEAQAMQHQCTCCQERRVHE 5715

Query: 2824 RSVQLFCATNATWVPYTVQEPTDCAC 2849
             +V L C  N + + +T     +C C
Sbjct: 5716 ETVPLHC-PNGSAILHTYTHVDECGC 5740



 Score = 84.3 bits (207), Expect = 2e-15
 Identities = 130/594 (21%), Positives = 210/594 (35%), Gaps = 61/594 (10%)

Query: 1429 PRTP-THRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTES 1487
            P TP T   A+  + P TT +   +T T     S G T T    P      ++   P  +
Sbjct: 4232 PSTPATSSTAMPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTAPPPKVLTSPATT 4291

Query: 1488 PASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSP 1547
            P +    A+  + P T  +++LPV   T T    S A   T +     G+        + 
Sbjct: 4292 PTATSSKATSSSSPRT--ATTLPVLTSTATK---STATSVTPIPSSTLGTTGTLPEQTTT 4346

Query: 1548 PAPRFPLMTKAVTVRGHGSLPVRTTPLQPSLTASPSSRPVASPGA--ISRSPTSSGSHKA 1605
            P      +  + T     +  V TT    +   S +S P ++PG   I    T++ +  A
Sbjct: 4347 PVATMSTIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTA 4406

Query: 1606 VLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKG 1665
               P  T        P  T   +        T   TA+     +P +T     +L+    
Sbjct: 4407 ATGPTAT--------PSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTTWILTEPST 4458

Query: 1666 EAGHSQPMGSPASPQPHPLPSAPPRPAQHTTM--ATRSPALPPETPAAASLSTATDGLAA 1723
             A  + P GS A+       +  P  +   T    T S A P  +P  A+   A    A 
Sbjct: 4459 TATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGTATALPALRSTAT 4518

Query: 1724 TPFMSLESTRPSQLLSGL---PPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLP 1780
            TP  +  +  PS  L         T+ P A + T+ P +TP    +V T+ +     T  
Sbjct: 4519 TPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTP---ETVHTSTVLTATATTT 4575

Query: 1781 AQTLSPVLPFT----------PAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVA 1830
              T S   P +          P   T     T  + P     P + +  T   +   P  
Sbjct: 4576 GATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTTTPTT 4635

Query: 1831 EGTASMVSVVPRKSTTGKV------AILSKQVSLPTSMYGSAEGGPTELTPATSHPLTPL 1884
             G+    S +P  + T +V       + +  ++ P+S   ++   P+  T AT+   T  
Sbjct: 4636 SGSTVTPSSIPGTTHTARVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGS 4695

Query: 1885 VAEPEGAQAGTAL-PVPTSYAL------SRVSARTAPQ--DSMLVLLPQLAEAHGTSAGP 1935
               P      T + PV TS A       S+ ++ ++P+   ++ VL     ++  TS  P
Sbjct: 4696 TTNPSSTPGTTPITPVLTSTATTPAATSSKATSSSSPRTATTLPVLTSTATKSTATSFTP 4755

Query: 1936 HLAAE-----PVDEATTEPSG-------RSAPALSIVEGLAEALATTTEANTST 1977
              ++       V   TT P          S P  +    +    AT T A  ST
Sbjct: 4756 IPSSTLWTTWTVPAQTTTPMSTMSTIHTSSTPETTHTSTVLTTTATMTRATNST 4809



 Score = 81.3 bits (199), Expect = 1e-14
 Identities = 103/371 (27%), Positives = 147/371 (39%), Gaps = 33/371 (8%)

Query: 1428 SPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTES 1487
            SP T T  PAL   A   TA     + T  P  S G   T L Q    TA+   A P+ +
Sbjct: 3218 SPGTATALPALRSTATTPTA----TSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPSST 3273

Query: 1488 PASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSP 1547
            P +   T+++L    T   ++  VA  + TPG        T  T  F  +P+ +  +   
Sbjct: 3274 PETVH-TSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALT 3332

Query: 1548 PAPRFPLMTKAVTVRGHGSLPVR---TTPLQPSLTASPSSRPVASPGAISRSPTSSGSHK 1604
            P P +   T   T RG    P     TT     LT + ++    S    S S  +SG+  
Sbjct: 3333 P-PVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTPP 3391

Query: 1605 AVLTPAVTKVISRTGVPQPTQAQSASSPSTPL------TVAGTAAEQVPVSPLATRSLEI 1658
            ++ T A T  I+ TG      +   ++P  P+      T A T++   P S L T     
Sbjct: 3392 SLTTTATT--ITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPP 3449

Query: 1659 VLSTEKGEAGHSQPMGSPASPQPHPLPSAPPRPAQH---TTMATRSPALPPETPAAASLS 1715
            V +T     G S P  SP     H + +A          TT  T    +   TPAA + +
Sbjct: 3450 VPNTTATTHGRSLPPSSP-----HTVRTAWTSATSGILGTTHITEPSTVTSHTPAATTST 3504

Query: 1716 TATDGLAATPFMSLESTRPSQLLSGLPPD--TSLPLAKVGTSAPVATPGPKASVITTPLQ 1773
            T      +TP  +L S  PS   +  PP   T+ P    GTS   AT  P  +  +T L 
Sbjct: 3505 TQH----STP--ALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPSKTRTSTLLP 3558

Query: 1774 PQATTLPAQTL 1784
               T+ P  T+
Sbjct: 3559 SSPTSAPITTV 3569



 Score = 80.9 bits (198), Expect = 2e-14
 Identities = 102/416 (24%), Positives = 154/416 (37%), Gaps = 67/416 (16%)

Query: 2019 GLAVRVGGDRCC---PLWECACR-----CSIFPDLSFVTFDGSHVALFKEAIYILSQSPD 2070
            G  +RV  + C      WEC+ R     C  + D  F+TFDG   +      YIL+Q   
Sbjct: 870  GETIRVDCNTCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYC 929

Query: 2071 EMLTVH-VLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSR 2129
               T H      + N+        C   + +   ++++ +     K         PP   
Sbjct: 930  GDNTTHGTFRIVTENIPCGTTGTTCSKAIKLFVESYELILQEGTFKAVARGPGGDPP--- 986

Query: 2130 YGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTL 2189
              ++I   G +++++    + + W   + + I    +  K +  GLCG  D +A ND   
Sbjct: 987  --YKIRYMG-IFLVIETHGMAVSWDRKTSVFI-RLHQDYKGRVCGLCGNFDDNAINDFAT 1042

Query: 2190 KDGSVVGGAEDPAPFLDSWQV----PSSLTSVGQTRFRP--DSCATTDCSPCLRMVSNRT 2243
            +  SVVG   D   F +SW++    P +L         P   S A   CS    ++   T
Sbjct: 1043 RSRSVVG---DALEFGNSWKLSPSCPDALAPKDPCTANPFRKSWAQKQCS----ILHGPT 1095

Query: 2244 FSACHRFVPPESFCELWIRDTKYVQQP------CVALTVYVAMCHKFHVCIEWRRSDYCP 2297
            F+AC   V    + E  + D             C A+  Y   CH   +C+ WR  D CP
Sbjct: 1096 FAACRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACHDAGLCVSWRTPDTCP 1155

Query: 2298 FLC-------SSDSTYQACVTACEPPKTCQDGILGPLDPEHCQV---LGEGCV--CSEGT 2345
              C         +  YQ C   C   KTC++         HC V     EGC   C    
Sbjct: 1156 LFCDFYNPHGGCEWHYQPCGAPC--LKTCRN------PSGHCLVDLPGLEGCYPKCPPSQ 1207

Query: 2346 ILHRRHSALCIPEAKCACTDSMG--------VPRALG-ETWNSSLSGC-CQHQCQA 2391
                     C+  A+C C D  G        VP A   ++ N + SG  C H  +A
Sbjct: 1208 PFFNEDQMKCV--AQCGCYDKDGNYYDVGARVPTAENCQSCNCTPSGIQCAHSLEA 1261



 Score = 77.4 bits (189), Expect = 2e-13
 Identities = 124/510 (24%), Positives = 182/510 (35%), Gaps = 88/510 (17%)

Query: 1429 PRTPTHRPALTPAA-PLTTALNPPVTATEEPVVSPGPTQTT---------LQQPLELTAS 1478
            P TP      TP++ P TT +   +T T     S G T T          L +P      
Sbjct: 3675 PSTPATSSTATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEPSTTATV 3734

Query: 1479 QLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSP 1538
             +P G T + +S   TA     PH   +++ P    +      S    T          P
Sbjct: 3735 TVPTGSTATASSTQATA---GTPHVSTTATTPTVTSSKATPFSSPGTAT--------ALP 3783

Query: 1539 NITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRTTPLQPSLTASPSSRP--VASPGAISRS 1596
             +  ++ +P A  F  +  +        L   TTP     TA+PSS P    +   ++ +
Sbjct: 3784 ALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTT 3843

Query: 1597 PTSSGSHKAVLTPAVTK-VISRTGVPQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRS 1655
             T++ +  +V TP+ T      T VP  T      +PS+              SP   R+
Sbjct: 3844 ATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSS--------------SPGTART 3889

Query: 1656 LEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPRPAQHTTMATRSPALPPETPAAASLS 1715
              + +ST       + P  S ++  P  +P     P   TT  T                
Sbjct: 3890 PPVWISTT------TTPTTSGSTVTPSSVPGTTHTPTVLTTTTT---------------- 3927

Query: 1716 TATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQ 1775
            T   G  ATP  S ++       SG PP  SL       +A  +T  P ++  TTP+ P 
Sbjct: 3928 TVATGSMATPSSSTQT-------SGTPP--SLITTATTITATGSTTNPSSTPGTTPIPPV 3978

Query: 1776 AT---TLPAQTLSPVLPFTPAAMTQAHP------PTH---IAPPAAGTAPGLLLGATLPT 1823
             T   T PA T S V P +    T   P       TH   ++P +  T       AT  T
Sbjct: 3979 LTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGT 4038

Query: 1824 SGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGSAEGGPTELTPATSHPL-- 1881
             G   + E +    S  P  +TTG     +  +S P     + E  P+  T    H    
Sbjct: 4039 LGTTHITEPSTG-TSHTP-AATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTAT 4096

Query: 1882 --TPLVAEPEGAQAGTALP-VPTSYALSRV 1908
              T   A P   +  T LP  PTS  ++ V
Sbjct: 4097 SRTTATATPSKTRTSTLLPSSPTSAPITTV 4126



 Score = 77.0 bits (188), Expect = 2e-13
 Identities = 158/690 (22%), Positives = 234/690 (33%), Gaps = 112/690 (16%)

Query: 1394 PAVWVPTEAL---GNETLPPSQG---------LPTPSDEEPQLSQESPRTPTHRPALTPA 1441
            P VW+ T         T+ PS           L T +      S  +P + T     TP 
Sbjct: 3890 PPVWISTTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSG-TPP 3948

Query: 1442 APLTTALNPPVT-ATEEPVVSPGPTQ------TTLQQPLELTASQLPA---GPTESPASK 1491
            + +TTA     T +T  P  +PG T       TT   P   +++  P+   G T +P   
Sbjct: 3949 SLITTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVP 4008

Query: 1492 GVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITV--------- 1542
              TA+      +P S   P  ++T      SG + TT +T    G+ +            
Sbjct: 4009 NTTATTHGRSLSPSS---PHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHS 4065

Query: 1543 ---------SSRSPPAPRFPLMTKAVTVRGHGSLPVRTTPLQ-PSLT-------ASPSSR 1585
                     SSR+  +P  P      T  GH +   RTT    PS T       +SP+S 
Sbjct: 4066 TPALSSPHPSSRTTESPPSP----GTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSA 4121

Query: 1586 PVASPGAISRSPTSSGSHKAVLT-----------PAVTKVISRTGV----PQPTQAQSAS 1630
            P+ +       P  + S     +              + + +  G     P   + ++ +
Sbjct: 4122 PITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQA 4181

Query: 1631 SPSTPLTVAGTAAEQVPVSPLATRSLEIV-------------LSTEKGEAGHSQPMGSPA 1677
             P  PL   G   E      L  R+ E V                  G    +    S A
Sbjct: 4182 QPGVPLGELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTA 4241

Query: 1678 SPQPHPLPS---APPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRP 1734
             P   P  +           TT +T S A P  TP  A         A TP  +      
Sbjct: 4242 MPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTAPPPKVLTSPATTPTATSSKATS 4301

Query: 1735 S---QLLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFT 1791
            S   +  + LP  TS       TS    TP P +++ TT   P+ TT P  T+S + P +
Sbjct: 4302 SSSPRTATTLPVLTSTATKSTATSV---TPIPSSTLGTTGTLPEQTTTPVATMSTIHPSS 4358

Query: 1792 PAAMTQAHPPTHIAPPAAGT-------APGLLLGATLPTSGVLPVAEGTASMVSVVPRKS 1844
                T  H  T +   A  T        P    G T   + +   A  TA+        S
Sbjct: 4359 TPETT--HTSTVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATGPTATPSS 4416

Query: 1845 TTGKVAILSKQVSLPTSMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYA 1904
            T G   IL++   L T+   +A  G T  TP+++   T ++ EP      T     T+ A
Sbjct: 4417 TPGTTWILTE---LTTTATTTASTGST-ATPSSTPGTTWILTEPSTTATVTVPTGSTATA 4472

Query: 1905 LSRVSARTAPQDSMLVLLPQLAEAHGT---SAGPHLAAEPVDEATTEPSGRS---APALS 1958
             S  +    P  S     P +  +  T   S G   A   +    T P+  S    P+ S
Sbjct: 4473 SSTQATAGTPHVSTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSFTAIPSSS 4532

Query: 1959 IVEGLAEALATTTEANTSTTCVPIAEQDCV 1988
            +         TTT   T +T  P +  + V
Sbjct: 4533 LGTTWTRLSQTTTPTATMSTATPSSTPETV 4562



 Score = 76.3 bits (186), Expect = 4e-13
 Identities = 96/389 (24%), Positives = 152/389 (39%), Gaps = 37/389 (9%)

Query: 1431 TPTHRPALTPAAPLTTALNPPVTATE-EPVVSPGPTQTTLQQPLELTASQLPAGPTESP- 1488
            T T R A  P    TTA  P VT+++  P  SPG T T L  P   + +  P   + +P 
Sbjct: 1930 TSTLRTAPPPKVLTTTATTPTVTSSKATPSSSPG-TATAL--PALRSTATTPTATSVTPI 1986

Query: 1489 --ASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRV---TVIFAGSPNITVS 1543
              +S G T + L+   TP ++     + T TP        T+ V   T    G+     +
Sbjct: 1987 PSSSLGTTWTRLSQTTTPTAT-----MSTATPSSTPETAHTSTVLTATATTTGATGSVAT 2041

Query: 1544 SRSPPAPRFPLMTKAVTVRGHGSLPVRT--TPLQPSLTASPSSRPVASPGAISRSPTSSG 1601
              S P           T  G  + P  +  T L P +  S ++ P      ++ S     
Sbjct: 2042 PSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGT 2101

Query: 1602 SHKA-VLTPAVTKVISRTGVPQPTQAQSASSP----STPLTVAGTAAEQVPVSPLATRSL 1656
            +H A VLT   T V + +     +  Q++ +P    +T  T+  T +   P S   T  +
Sbjct: 2102 THTATVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPI 2161

Query: 1657 EIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPRPAQHTTMATRSPALPPETP--AAASL 1714
              VL+T       +    +P+S     L +    P  +T   T   +LPP +P     + 
Sbjct: 2162 PPVLTTTATTPAATSNTVTPSS----ALGTTHTPPVPNTMATTHGRSLPPSSPHTVRTAW 2217

Query: 1715 STATDGLAATPFMSLESTRPSQLLSGLPPDT--SLPLAKVGTSAPVATPGPKASVITTPL 1772
            ++AT G+  T  ++  ST  S  L+     T  S P       +   T  P +   TTP 
Sbjct: 2218 TSATSGILGTTHITEPSTVTSHTLAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPG 2277

Query: 1773 QPQATTLPAQTLSP-------VLPFTPAA 1794
               AT+    T +P       +LP +P +
Sbjct: 2278 HTTATSRTTATATPSKTRTSTLLPSSPTS 2306



 Score = 75.9 bits (185), Expect = 5e-13
 Identities = 152/652 (23%), Positives = 219/652 (33%), Gaps = 85/652 (13%)

Query: 1399 PTEALGNETLPPSQGLPTPSDEEPQLSQESPRTP-THRPALTPAAPLTTALNPPVTATEE 1457
            P+ ALG    PP     T +     L   SP T  T   + T     TT +  P T T  
Sbjct: 3438 PSSALGTTHTPPVPNT-TATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSH 3496

Query: 1458 PVVSPGPTQTTLQQPLELTASQLPAG-PTESPASKGVTASLLAIPHTPESSSLPVALQTP 1516
               +P  T +T Q      +S  P+   TESP S G T      P     +S   A  TP
Sbjct: 3497 ---TPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTT-----PGHTRGTSRTTATATP 3548

Query: 1517 TPGMVSGAMETTRV-----TVIFAG-SPNITVS-----SRSPPAPRFPLMTKAVTVRGHG 1565
            +    S  + ++       TV+  G  P    S     S   P P          +R  G
Sbjct: 3549 SKTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAG 3608

Query: 1566 SLPVRTTPL--------QPSLTASPSSRPVASP---GAISRSPTSSGSHKAVLTPAVTKV 1614
               V   PL        QP +      + V      G + R+    G  K      +   
Sbjct: 3609 GA-VCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVF 3667

Query: 1615 ISRTG-VPQPTQAQSASSPS---------TPLTVAGTAAEQV--PVSPLATRSLEIVLST 1662
                G  P      S ++PS         T LT   T  E      +P +T     +L+ 
Sbjct: 3668 CCNYGHCPSTPATSSTATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTE 3727

Query: 1663 EKGEAGHSQPMGSPASPQPHPLPSAPPRPAQHTTM--ATRSPALPPETPAAASLSTATDG 1720
                A  + P GS A+       +  P  +   T    T S A P  +P  A+   A   
Sbjct: 3728 PSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRS 3787

Query: 1721 LAATPFMSLESTRPSQLLSGL---PPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQAT 1777
             A TP  +  +  PS  L         T+ P A + T+ P +TP  + +  +T L   AT
Sbjct: 3788 TATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTP--ETAHTSTVLTTTAT 3845

Query: 1778 TLPAQTLSPVLPFTPAAMTQAHPPTHI----------APPAAGTAPGLLLGATLPTSGVL 1827
            T  A         TP        PT            +P  A T P  +   T PT+   
Sbjct: 3846 TTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGS 3905

Query: 1828 PVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGSAEGGPTELTPATSHPLTPLVAE 1887
             V   +    +  P   TT    + +  ++ P+S   ++   P+ +T AT+   T     
Sbjct: 3906 TVTPSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLITTATTITATGSTTN 3965

Query: 1888 PEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLAEAHGTSAGPHLAAEPVDEATT 1947
            P      T +P   +      +  T P  +   + P  + A GT+  P     PV   T 
Sbjct: 3966 PSSTPGTTPIPPVLT------TTATTPAATSSTVTP--SSALGTTHTP-----PVPNTTA 4012

Query: 1948 EPSGRSAPALS-------IVEGLAEALATT--TEANTSTTCVPIAEQDCVRH 1990
               GRS    S            +  L TT  TE +T T+  P A     +H
Sbjct: 4013 TTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQH 4064



 Score = 75.1 bits (183), Expect = 9e-13
 Identities = 115/438 (26%), Positives = 162/438 (36%), Gaps = 44/438 (10%)

Query: 1501 PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSS-RSPPAPRFPLMTKAV 1559
            P TP +SS      TP    +     TT  T    GS     S+ R+ P P+  ++T   
Sbjct: 1889 PSTPATSSTATPSSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPK--VLTTTA 1946

Query: 1560 TVRGHGSLPVRTTPLQPSLTASPSSRPVA-SPGAISRSPTSSGS-------HKAVLTPAV 1611
            T     S     +    + TA P+ R  A +P A S +P  S S            TP  
Sbjct: 1947 TTPTVTSSKATPSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPTA 2006

Query: 1612 TKVISRTGVPQPTQAQSASSPSTPLTVAGTAAEQVPVS-PLATRSLEIVLSTEKGEAGHS 1670
            T   +       T   S    +T  T   T +   P S P    + ++  +T  G    +
Sbjct: 2007 TMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFT--A 2064

Query: 1671 QPMGSPASPQPHPL-PSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSL 1729
             P  SP +    P+  S    P   T  +T +P+  P T   A++ T T    AT  M+ 
Sbjct: 2065 TPSSSPGTALTPPVWISTTTTPT--TRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMAT 2122

Query: 1730 ESTRPSQLLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQAT---TLPAQTLSP 1786
             S+  S   SG PP  SL       +A  +T  P ++  TTP+ P  T   T PA T + 
Sbjct: 2123 PSS--STQTSGTPP--SLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSNT 2178

Query: 1787 VLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLP----------TSGVLPVAEGT-AS 1835
            V P +    T   P     P    T  G  L  + P          TSG+L     T  S
Sbjct: 2179 VTPSSALGTTHTPP----VPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPS 2234

Query: 1836 MVSVVPRKSTTGKVAILSKQVSLPTSMYGSAEGGPTELTPATSHPL----TPLVAEPEGA 1891
             V+     +TTG     +  +S P     + E  P+  T    H      T   A P   
Sbjct: 2235 TVTSHTLAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKT 2294

Query: 1892 QAGTALP-VPTSYALSRV 1908
            +  T LP  PTS  ++ V
Sbjct: 2295 RTSTLLPSSPTSAPITTV 2312



 Score = 75.1 bits (183), Expect = 9e-13
 Identities = 131/571 (22%), Positives = 205/571 (35%), Gaps = 60/571 (10%)

Query: 1398 VPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEE 1457
            +P+ +LG      SQ     +         +P T      LT  A  T A     T    
Sbjct: 4528 IPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTATATTTGATGSVAT---- 4583

Query: 1458 PVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQTPT 1517
            P  +PG   TT  +    T +   A P+ SP +       ++   TP +++   +  T T
Sbjct: 4584 PSSTPGTAHTT--KVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTTTPTTSGSTVT 4641

Query: 1518 PGMVSGAMETTRV-----TVIFAGS----PNITVSSRSPPAPRFPLMTKAVTVRGHGSLP 1568
            P  + G   T RV     T +  GS     + T +S +PP+    L T A T+   GS  
Sbjct: 4642 PSSIPGTTHTARVLTTTTTTVATGSMATPSSSTQTSGTPPS----LTTTATTITATGSTT 4697

Query: 1569 -----VRTTPLQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLT-PAVTKVISRTGVPQ 1622
                   TTP+ P LT++       +P A S   TSS S +   T P +T   +++    
Sbjct: 4698 NPSSTPGTTPITPVLTST-----ATTPAATSSKATSSSSPRTATTLPVLTSTATKS---- 4748

Query: 1623 PTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPH 1682
             T       PS+ L    T   Q   +P++T S     ST   E  H+  + +  +    
Sbjct: 4749 -TATSFTPIPSSTLWTTWTVPAQT-TTPMSTMSTIHTSSTP--ETTHTSTVLTTTATMTR 4804

Query: 1683 PLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLP 1742
               S     +   T    +      T  AA+ STAT  L++TP  +   T PS + + + 
Sbjct: 4805 ATNSTATPSSTLGTTRILTELTTTATTTAATGSTAT--LSSTPGTTWILTEPSTIATVMV 4862

Query: 1743 PDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHPPT 1802
            P  S   A   T     TP    ++ T P    +T   + T+      TPA +  + P  
Sbjct: 4863 PTGSTATAS-STLGTAHTPKVVTTMATMPTATASTVPSSSTVGTTR--TPAVLPSSLPTF 4919

Query: 1803 HIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSM 1862
             ++  ++          TL  +G       T        +  + G+V I +K        
Sbjct: 4920 SVSTVSSSVL------TTLRPTGFPSSHFSTPCFCRAFGQFFSPGEV-IYNKTDRAGCHF 4972

Query: 1863 YGSAE----------GGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSART 1912
            Y                PT   P +S PL+     P    A     V  ++ L   +   
Sbjct: 4973 YAVCNQHCDIDRFQGACPTSPPPVSSAPLSSPSPAPGCDNAIPLRQVNETWTLENCTVAR 5032

Query: 1913 APQDSMLVLLPQLAEAHGTSAGPHLAAEPVD 1943
               D+ +VLL     A+ T    HL  +  D
Sbjct: 5033 CVGDNRVVLLDPKPVANVTCVNKHLPIKVSD 5063



 Score = 73.9 bits (180), Expect = 2e-12
 Identities = 103/371 (27%), Positives = 148/371 (39%), Gaps = 33/371 (8%)

Query: 1428 SPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTES 1487
            SP T T  PAL   A   TA     + T  P  S G T T L Q    TA+   A P+ +
Sbjct: 2518 SPGTATALPALRSTATTPTA----TSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSST 2573

Query: 1488 PASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSP 1547
            P +   T+++L    T   ++  VA  + TPG        T  T  F  +P+ +  + + 
Sbjct: 2574 PETVH-TSTVLTTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGT-AR 2631

Query: 1548 PAPRFPLMTKAVTVRGHGSLPVR---TTPLQPSLTASPSSRPVASPGAISRSPTSSGSHK 1604
              P +   T   T RG    P     TT     LT + ++    S    S S  +SG+  
Sbjct: 2632 TLPVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPP 2691

Query: 1605 AVLTPAVTKVISRTGVPQPTQAQSASSPSTPL------TVAGTAAEQVPVSPLATRSLEI 1658
            ++ T A T  I+ TG      +   ++P  P+      T A T++   P S L T     
Sbjct: 2692 SLTTTATT--ITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPP 2749

Query: 1659 VLSTEKGEAGHSQPMGSPASPQPHPLPSAPPRPAQHT---TMATRSPALPPETPAAASLS 1715
            V +T     G S    SP+SP  H + +A       T   T  T        TPAA + +
Sbjct: 2750 VPNTTATTHGRSL---SPSSP--HTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGT 2804

Query: 1716 TATDGLAATPFMSLESTRPSQLLSGLPPD--TSLPLAKVGTSAPVATPGPKASVITTPLQ 1773
            T      +TP  +L S  PS   +  PP   T+ P     TS   AT  P  +  +T L 
Sbjct: 2805 TQH----STP--ALSSPHPSSRTTESPPSPGTTTPGHTRATSRTTATATPSKTRTSTLLP 2858

Query: 1774 PQATTLPAQTL 1784
               T+ P  T+
Sbjct: 2859 SSPTSAPITTV 2869



 Score = 73.6 bits (179), Expect = 3e-12
 Identities = 143/597 (23%), Positives = 210/597 (35%), Gaps = 87/597 (14%)

Query: 1423 QLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLP- 1481
            +LSQ +  T T   A   + P T   +  +TAT     + G   T    P     +++P 
Sbjct: 1997 RLSQTTTPTATMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPT 2056

Query: 1482 ---AGPTESPASKGVTASLLAIPHTPESSSLPVAL-QTPTPGMVSGAME-----TTRVTV 1532
                G T +P+S   TA  L  P    +++ P     T TP  + G        TT  T 
Sbjct: 2057 TTTTGFTATPSSSPGTA--LTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTT 2114

Query: 1533 IFAGS----PNITVSSRSPPAPRFPLMTKAVTVRGHGSL-----PVRTTPLQPSLTASPS 1583
            +  GS     + T +S +PP+    L T A T+   GS         TTP+ P LT +  
Sbjct: 2115 VATGSMATPSSSTQTSGTPPS----LTTTATTITATGSTTNPSSTPGTTPIPPVLTTT-- 2168

Query: 1584 SRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTAA 1643
                 +P A S + T S +     TP V   ++ T      ++   SSP T  T   +A 
Sbjct: 2169 ---ATTPAATSNTVTPSSALGTTHTPPVPNTMATT----HGRSLPPSSPHTVRTAWTSAT 2221

Query: 1644 EQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPRPAQHTTMATRSPA 1703
              +  +   T    +   T     G +Q   +PA   PHP           ++  T SP 
Sbjct: 2222 SGILGTTHITEPSTVTSHTLAATTGTTQ-HSTPALSSPHP-----------SSRTTESPP 2269

Query: 1704 LPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAPVATPGP 1763
             P  T    + +T+     ATP      TR S LL   P           TSAP+ T   
Sbjct: 2270 SPGTTTPGHTTATSRTTATATP----SKTRTSTLLPSSP-----------TSAPITT--- 2311

Query: 1764 KASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAP-GLLLGAT-- 1820
               V+T   +PQ         S  +P         +     A  A    P GL   A   
Sbjct: 2312 ---VVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQ 2368

Query: 1821 --LPTSGVLPVAEGTASMVSVVPRKSTTGKVAI-LSKQVSLPTSMYGSAEGGPT------ 1871
              +P   +  V E +     V   +   GK  +  + ++ +    YG     P       
Sbjct: 2369 PGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAM 2428

Query: 1872 -ELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLAEAHG 1930
               TP T+  LT L       ++  +   P+S         T P  +  V +P  + A  
Sbjct: 2429 PSSTPGTTWILTELTTTATTTESTGSTATPSS-TPGTTWILTEPSTTATVTVPTGSTATA 2487

Query: 1931 TSAGPHLAAEPVDEATTEPSGRSAPALSIVE-GLAEAL-----ATTTEANTSTTCVP 1981
            +S         V    T P+  S+ A      G A AL       TT   TS T +P
Sbjct: 2488 SSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIP 2544



 Score = 70.9 bits (172), Expect = 2e-11
 Identities = 138/606 (22%), Positives = 203/606 (33%), Gaps = 97/606 (16%)

Query: 1398 VPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEE 1457
            +P+ +LG      SQ     +         +P T      LT  A  T A     T +  
Sbjct: 3800 IPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTTRATGSVATPSST 3859

Query: 1458 P----------VVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESS 1507
            P            + G T T    P       +    T +P + G T +  ++P T  + 
Sbjct: 3860 PGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVPGTTHT- 3918

Query: 1508 SLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSL 1567
              P  L T T  + +G+M T           + T +S +PP+    L+T A T+   GS 
Sbjct: 3919 --PTVLTTTTTTVATGSMAT---------PSSSTQTSGTPPS----LITTATTITATGST 3963

Query: 1568 -----PVRTTPLQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQ 1622
                    TTP+ P LT +       +P A S + T S +     TP V    +      
Sbjct: 3964 TNPSSTPGTTPIPPVLTTT-----ATTPAATSSTVTPSSALGTTHTPPVPNTTA------ 4012

Query: 1623 PTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPH 1682
             T    + SPS+P TV  TA        L T  +     TE        P  +  + Q  
Sbjct: 4013 -TTHGRSLSPSSPHTVR-TAWTSATSGTLGTTHI-----TEPSTGTSHTPAATTGTTQHS 4065

Query: 1683 PLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLP 1742
                + P P+  T   T SP  P  T    + +T+     ATP      TR S LL   P
Sbjct: 4066 TPALSSPHPSSRT---TESPPSPGTTTPGHTTATSRTTATATP----SKTRTSTLLPSSP 4118

Query: 1743 PDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHPPT 1802
                       TSAP+ T      V+TT  +PQ         S  +P         +   
Sbjct: 4119 -----------TSAPITT------VVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNI 4161

Query: 1803 HIAPPAAGTAP-GLLLGAT----LPTSGVLPVAEGTASMVSVVPRKSTTGKVAI-LSKQV 1856
              A  A    P GL   A     +P   +  V E +     V   +   GK  +  + ++
Sbjct: 4162 RAAGGAVCEQPLGLECRAQAQPGVPLGELGQVVECSLDFGLVCRNREQVGKFKMCFNYEI 4221

Query: 1857 SLPTSMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQD 1916
             +    YG         TPATS    P  + P      T L    +   S  S  T    
Sbjct: 4222 RVFCCNYGHCPS-----TPATSSTAMP-SSTPGTTWILTELTTTATTTASTGSTATP--- 4272

Query: 1917 SMLVLLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTS 1976
                     +   GT+  P +   P    T   S  ++ +          L +T   +T+
Sbjct: 4273 ---------SSTPGTAPPPKVLTSPATTPTATSSKATSSSSPRTATTLPVLTSTATKSTA 4323

Query: 1977 TTCVPI 1982
            T+  PI
Sbjct: 4324 TSVTPI 4329



 Score = 70.1 bits (170), Expect = 3e-11
 Identities = 147/634 (23%), Positives = 213/634 (33%), Gaps = 100/634 (15%)

Query: 1403 LGNETLPPSQGLPTPS--------DEEPQLSQESPRTPTHRPALTPAA----PLTTALNP 1450
            +   TLP    LP  +         + P L+  +  T   RP  T +     PLTT+L P
Sbjct: 1691 VATSTLPTRSALPGTTGSLGTWRPSQPPTLAPTTMATSRARPTGTASTASKEPLTTSLAP 1750

Query: 1451 PVTA---TEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESS 1507
             +T+   T +   S   T+TT+  PL           T +  S+G T        T    
Sbjct: 1751 TLTSELSTSQAETSTPRTETTMS-PL-----------TNTTTSQGTTRCQPKCEWTEWFD 1798

Query: 1508 SLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSL 1567
                 +  PT G+  G MET        G       S    A  +P     V++   G  
Sbjct: 1799 -----VDFPTSGVAGGDMETFENIRAAGGKMCWAPKSIECRAENYP----EVSIDQVGQ- 1848

Query: 1568 PVRTTPLQPSLTASPSSRPVASPGAIS---------------RSPTSSGSHKAVLTPAVT 1612
             V T  L+  LT     +        +                +P +S +     TP  T
Sbjct: 1849 -VLTCSLETGLTCKNEDQTGRFNMCFNYNVRVLCCDDYSHCPSTPATSSTATPSSTPGTT 1907

Query: 1613 KVISRTGVPQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATR----SLEIVLSTEKGEAG 1668
             ++++      T A S  S +TP +   TA     ++  AT     S +   S+  G A 
Sbjct: 1908 WILTKPTTTATTTA-STGSTATPTSTLRTAPPPKVLTTTATTPTVTSSKATPSSSPGTAT 1966

Query: 1669 HSQPMGS----PASPQPHPLPSAP-----PRPAQHTT-MATRSPALPPETPAAASLSTAT 1718
                + S    P +    P+PS+       R +Q TT  AT S A P  TP  A  ST  
Sbjct: 1967 ALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVL 2026

Query: 1719 DGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVG--TSAPVATPGPKASVITTPLQPQA 1776
               A T   +     PS    G    T +P       T+ P ++PG   + +T P+    
Sbjct: 2027 TATATTTGATGSVATPSST-PGTAHTTKVPTTTTTGFTATPSSSPG---TALTPPVWIST 2082

Query: 1777 TTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASM 1836
            TT P    S V P +              P    TA  L    T   +G +     +   
Sbjct: 2083 TTTPTTRGSTVTPSS-------------IPGTTHTATVLTTTTTTVATGSMATPSSSTQT 2129

Query: 1837 VSVVPRKSTTGKVAILSKQVSLPTSMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTA 1896
                P  +TT      +   + P+S  G+    P   T AT+   T     P  A   T 
Sbjct: 2130 SGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSNTVTPSSALGTTH 2189

Query: 1897 LPVPTSYALSRVSARTAPQDSMLVLLPQLAEAHGTSAGPHLAAEPVD------EATTEPS 1950
             P P    ++    R+ P  S   +      A     G     EP         ATT  +
Sbjct: 2190 TP-PVPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTLAATTGTT 2248

Query: 1951 GRSAPALSIVEGLAEAL------ATTTEANTSTT 1978
              S PALS     +          TTT  +T+ T
Sbjct: 2249 QHSTPALSSPHPSSRTTESPPSPGTTTPGHTTAT 2282



 Score = 69.7 bits (169), Expect = 4e-11
 Identities = 109/448 (24%), Positives = 168/448 (37%), Gaps = 53/448 (11%)

Query: 1397 WVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATE 1456
            W+ TE     T+     +PT S      +Q +  TP            TTA  P VT+++
Sbjct: 3723 WILTEPSTTATVT----VPTGSTATASSTQATAGTPHVS---------TTATTPTVTSSK 3769

Query: 1457 -EPVVSPGPTQTTLQQPLELTASQLPAGPTESPASK-GVTASLLAIPHTPESS-SLPVAL 1513
              P  SPG T T L        +      T  P+S  G T + L+   TP ++ S     
Sbjct: 3770 ATPFSSPG-TATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPS 3828

Query: 1514 QTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRT-- 1571
             TP     S  + TT  T    GS     +  S P           T  G    P  +  
Sbjct: 3829 STPETAHTSTVLTTTATTTRATGS---VATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPG 3885

Query: 1572 TPLQPSLTASPSSRPVASPGAISRSPTSSGSH-KAVLTPAVTKVISRTGVPQPTQAQSAS 1630
            T   P +  S ++ P  S   ++ S     +H   VLT   T V + +     +  Q++ 
Sbjct: 3886 TARTPPVWISTTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSG 3945

Query: 1631 SP----STPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPS 1686
            +P    +T  T+  T +   P S   T  +  VL+T       +    +P+S     L +
Sbjct: 3946 TPPSLITTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSS----ALGT 4001

Query: 1687 APPRPAQHTTMATRSPALPPETP--AAASLSTATDGLAATPFMSLESTRPSQLLSGLPPD 1744
                P  +TT  T   +L P +P     + ++AT G   T  ++  ST  S         
Sbjct: 4002 THTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSH-------- 4053

Query: 1745 TSLPLAKVGT---SAP-VATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHP 1800
               P A  GT   S P +++P P +    +P  P  TT P  T +     T A  T +  
Sbjct: 4054 --TPAATTGTTQHSTPALSSPHPSSRTTESPPSP-GTTTPGHTTA--TSRTTATATPSKT 4108

Query: 1801 PTHIAPPAAGTAPGLLLGATLPTSGVLP 1828
             T    P++ T+  +    T+ T+G  P
Sbjct: 4109 RTSTLLPSSPTSAPI---TTVVTTGCEP 4133



 Score = 69.3 bits (168), Expect = 5e-11
 Identities = 76/304 (25%), Positives = 111/304 (36%), Gaps = 46/304 (15%)

Query: 904  CTLH-PCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDV--SFSVIVENVNCYSS 960
            C  H  C   C+ +G  HY TFDG  + F G C   L++       + S+ ++N  C +S
Sbjct: 5068 CDFHYECECICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTAS 5127

Query: 961  GMI----CRKFISINVGN---------------SLIVFDDDSGNPSPESFLDDKQEVHTW 1001
                   C + +SI+  +                LI+FD       P S    K  V   
Sbjct: 5128 ATAAAARCPRALSIHYKSMDIVLTVTMVHGKEEGLILFDQ-----IPVSSGFSKNGVLVS 5182

Query: 1002 RVGFFTL-VHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNF-----------DLKT 1049
             +G  T+ V  P   +++ ++ +          +     G CG             D  T
Sbjct: 5183 VLGTTTMRVDIPALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTT 5242

Query: 1050 INEMRTPENLELTNPQEFGSSWAAVECPDTLDPRDMCVLNPLREPFAKKE-CSILLSEVF 1108
                +      L         WA    P T  P       P   P   +  C ++LS+VF
Sbjct: 5243 AASCKDMAKTWLVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQPLCDLMLSQVF 5302

Query: 1109 EICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWR--TPRLC 1166
              CH +V    F++ C++D C     G  E  C S+ AYA  C   GV  DWR  T  LC
Sbjct: 5303 AECHNLVPPGPFFNACISDHC----RGRLEVPCQSLEAYAELCRARGVCSDWRGATGGLC 5358

Query: 1167 PYDC 1170
               C
Sbjct: 5359 DLTC 5362



 Score = 68.9 bits (167), Expect = 7e-11
 Identities = 145/624 (23%), Positives = 223/624 (35%), Gaps = 103/624 (16%)

Query: 1407 TLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQ 1466
            T PP+  L T +    Q    +P+ PT  P LT A        PP + T  P +S G T 
Sbjct: 1612 TPPPTTELETATTTTTQALFSTPQ-PTSSPGLTRA--------PPASTTAVPTLSEGLTS 1662

Query: 1467 TTLQQPLELTAS---QLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSG 1523
                  L    +     PAG TE P   GV  S L     P  S+LP           +G
Sbjct: 1663 PRYTSTLGTATTGGPTTPAGSTE-PTVPGVATSTL-----PTRSALPGT---------TG 1707

Query: 1524 AMETTRVTVIFAGSPNITVSSRSPP------APRFPLMTKAVTVRGHGSLPVRTTPLQPS 1577
            ++ T R +     +P    +SR+ P      A + PL T           P  T+ L  S
Sbjct: 1708 SLGTWRPSQPPTLAPTTMATSRARPTGTASTASKEPLTTSLA--------PTLTSELSTS 1759

Query: 1578 LTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPST--P 1635
               + + R   +   ++ + TS G+ +       T+      V  PT   +     T   
Sbjct: 1760 QAETSTPRTETTMSPLTNTTTSQGTTRCQPKCEWTEWFD---VDFPTSGVAGGDMETFEN 1816

Query: 1636 LTVAG-----------TAAEQVP------VSPLATRSLEIVLSTEKGEAGHSQPMGSPAS 1678
            +  AG             AE  P      V  + T SLE  L+ +  +      M    +
Sbjct: 1817 IRAAGGKMCWAPKSIECRAENYPEVSIDQVGQVLTCSLETGLTCKNEDQTGRFNMCFNYN 1876

Query: 1679 PQPHPLPSAPPRPAQHTTMATRSPALPPET------PAAASLSTATDGLAATPFMSLEST 1732
             +          P+   T +T +P+  P T      P   + +TA+ G  ATP  +L + 
Sbjct: 1877 VRVLCCDDYSHCPSTPATSSTATPSSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTA 1936

Query: 1733 RPSQLLSGLPPDTSLPLAKVGTSAPVATPGPKA------SVITTPLQPQATTLPAQTLSP 1786
             P ++L+      + P      + P ++PG         S  TTP     T +P+ +L  
Sbjct: 1937 PPPKVLT---TTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSVTPIPSSSLGT 1993

Query: 1787 V-----LPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVP 1841
                     TP A      P+   P  A T+   +L AT  T+G    A G+ +  S  P
Sbjct: 1994 TWTRLSQTTTPTATMSTATPSS-TPETAHTS--TVLTATATTTG----ATGSVATPSSTP 2046

Query: 1842 RKSTTGKVAILSKQ--VSLPTSMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPV 1899
              + T KV   +     + P+S  G+A   P  ++  T+         P      +++P 
Sbjct: 2047 GTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTP------SSIPG 2100

Query: 1900 PTSYALSRVSARTAPQDSMLVLLPQLAEAHGTSAGPHLAAEPVDE--ATTEPSGRSAPAL 1957
             T  A    +  T      +       +  GT       A  +    +TT PS  S P  
Sbjct: 2101 TTHTATVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPS--STPGT 2158

Query: 1958 SIVEGLAEALATTTEANTSTTCVP 1981
            + +  +    ATT  A TS T  P
Sbjct: 2159 TPIPPVLTTTATTPAA-TSNTVTP 2181



 Score = 68.9 bits (167), Expect = 7e-11
 Identities = 112/466 (24%), Positives = 166/466 (35%), Gaps = 75/466 (16%)

Query: 1429 PRTP-THRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTTLQQP------LELTASQLP 1481
            P TP T   A+  + P TT +   +T T     S G T T    P       E + +   
Sbjct: 2418 PSTPATSSTAMPSSTPGTTWILTELTTTATTTESTGSTATPSSTPGTTWILTEPSTTATV 2477

Query: 1482 AGPTESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNIT 1541
              PT S A+   T +    PH   +++ P    +      S    T          P + 
Sbjct: 2478 TVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATAL--------PALR 2529

Query: 1542 VSSRSPPAPRFPLMTKAVTVRGHGSLPVRTTPLQPSLTASPSSRP--VASPGAISRSPTS 1599
             ++ +P A  F  +  +        L   TTP     TA+PSS P  V +   ++ + T+
Sbjct: 2530 STATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATT 2589

Query: 1600 SGSHKAVLTPA-------VTKVISRT-----GVPQPTQAQSASSP---STPLTVAGTAAE 1644
            +G+  +V TP+        TKV++ T       P  +   + + P   ST  T     + 
Sbjct: 2590 TGATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTPTTRGST 2649

Query: 1645 QVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPRPAQHTTM----ATR 1700
              P S   T     VL+T           GS A+P      S  P P+  TT     AT 
Sbjct: 2650 VTPSSIPGTTHTPTVLTTTTTTVA----TGSMATPSSSTQTSGTP-PSLTTTATTITATG 2704

Query: 1701 SPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLS-----------------GLPP 1743
            S   P  TP    +       A TP  +  +  PS  L                   L P
Sbjct: 2705 STTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSP 2764

Query: 1744 DTSLPLAKVGTSAPVATPGPKASVITTPLQ-----PQATTLPAQTLSPVLPFTPAAMTQA 1798
             +   +    TSA   T G   + IT P       P ATT   Q  +P       A++  
Sbjct: 2765 SSPHTVRTAWTSATSGTLG--TTHITEPSTGTSHTPAATTGTTQHSTP-------ALSSP 2815

Query: 1799 HPP--THIAPPAAG-TAPGLLLGATLPTSGVLPVAEGTASMVSVVP 1841
            HP   T  +PP+ G T PG     +  T+   P    T++++   P
Sbjct: 2816 HPSSRTTESPPSPGTTTPGHTRATSRTTATATPSKTRTSTLLPSSP 2861



 Score = 67.8 bits (164), Expect = 1e-10
 Identities = 84/375 (22%), Positives = 135/375 (36%), Gaps = 36/375 (9%)

Query: 2039 CSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVML 2098
            CS + D  + TFDG          Y+ S+          +  +   +G         V+ 
Sbjct: 77   CSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCRAAYEDFNVQLRRGLVGSRP------VVT 130

Query: 2099 NMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSG 2158
             +   A  + ++  N  V ++ Q    P SR G  +E +G    +     +   W +   
Sbjct: 131  RVVIKAQGLVLEASNGSVLINGQREELPYSRTGLLVEQSGDYIKVSIRLVLTFLW-NGED 189

Query: 2159 LMIVEASKTSKAQGHGLCGICDG-DAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSV 2217
              ++E       Q  GLCG  +G  A N+    +  +      P  F +  ++       
Sbjct: 190  SALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLT-----PLQFGNLQKLDGPTEQC 244

Query: 2218 GQTRFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDT-KYVQQPCVALTV 2276
                  P    T +   C R +    F+ CH  V   ++     +D  +    PC     
Sbjct: 245  PDPLPLPAGNCTDEEGICHRTLLGPAFAECHALVDSTAYLAACAQDLCRCPTCPCATFVE 304

Query: 2277 YVAMC-HKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVL 2335
            Y   C H       WR  + CP  C  +  +Q C + C    TC +     L  +HC   
Sbjct: 305  YSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPC--TDTCSNPQRAQLCEDHCV-- 360

Query: 2336 GEGCVCSEG---TILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGC-CQ---HQ 2388
             +GC C  G   T+L     + C+P  +C CT   G   + G ++N++ S C C     Q
Sbjct: 361  -DGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHG-GRTYSPGTSFNTTCSSCTCSGGLWQ 418

Query: 2389 CQAPDTIVPVDLGCP 2403
            CQ        DL CP
Sbjct: 419  CQ--------DLPCP 425



 Score = 66.6 bits (161), Expect = 3e-10
 Identities = 153/654 (23%), Positives = 221/654 (33%), Gaps = 89/654 (13%)

Query: 1399 PTEALGNETLPPSQGLPTPSDEEPQLSQESPRTP-THRPALTPAAPLTTALNPPVTATEE 1457
            P+ ALG    PP       +     L   SP T  T   + T     TT +  P T T  
Sbjct: 2181 PSSALGTTHTPPVPNTMATTHGR-SLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSH 2239

Query: 1458 PVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQTPT 1517
             + +   T TT      L++    +  TESP S G T      P    ++S   A  TP+
Sbjct: 2240 TLAAT--TGTTQHSTPALSSPHPSSRTTESPPSPGTTT-----PGHTTATSRTTATATPS 2292

Query: 1518 --------PGMVSGAMETTRVTVIFAGSPNITVS-----SRSPPAPRFPLMTKAVTVRGH 1564
                    P   + A  TT VT+     P    S     S   P P          +R  
Sbjct: 2293 KTRTSTLLPSSPTSAPITTVVTM--GCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAA 2350

Query: 1565 GSLPVRTTPL--------QPSLTASPSSRPVASP---GAISRSPTSSGSHKAVLTPAVTK 1613
            G   V   PL        QP +      + V      G + R+    G  K      +  
Sbjct: 2351 GGA-VCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRV 2409

Query: 1614 VISRTG-VPQPTQAQSASSPS---------TPLTVAGTAAEQV--PVSPLATRSLEIVLS 1661
                 G  P      S + PS         T LT   T  E      +P +T     +L+
Sbjct: 2410 FCCNYGHCPSTPATSSTAMPSSTPGTTWILTELTTTATTTESTGSTATPSSTPGTTWILT 2469

Query: 1662 TEKGEAGHSQPMGSPASPQPHPLPSAPPRPAQHTTM--ATRSPALPPETPAAASLSTATD 1719
                 A  + P GS A+       +  P  +   T    T S A P  +P  A+   A  
Sbjct: 2470 EPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALR 2529

Query: 1720 GLAATPFMSLESTRPSQLLSGL---PPDTSLPLAKVGTSAPVATPGP--KASVITTPLQP 1774
              A TP  +  +  PS  L         T+ P A + T+ P +TP     ++V+TT    
Sbjct: 2530 STATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATT 2589

Query: 1775 QATT----LPAQT-----LSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSG 1825
               T     P+ T      + VL  T    T A P +  +P  A T P  +   T PT+ 
Sbjct: 2590 TGATGSVATPSSTPGTAHTTKVLTTTTTGFT-ATPSS--SPGTARTLPVWISTTTTPTTR 2646

Query: 1826 VLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGSAEGGPTELTPATSHPLTPLV 1885
               V   +    +  P   TT    + +  ++ P+S   ++   P+  T AT+   T   
Sbjct: 2647 GSTVTPSSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGST 2706

Query: 1886 AEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLAEAHGTSAGPHLAAEPVDEA 1945
              P      T +P   +      +  T P  +   + P  + A GT+  P     PV   
Sbjct: 2707 TNPSSTPGTTPIPPVLT------TTATTPAATSSTVTP--SSALGTTHTP-----PVPNT 2753

Query: 1946 TTEPSGRSAPALS-------IVEGLAEALATT--TEANTSTTCVPIAEQDCVRH 1990
            T    GRS    S            +  L TT  TE +T T+  P A     +H
Sbjct: 2754 TATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQH 2807



 Score = 66.2 bits (160), Expect = 4e-10
 Identities = 118/555 (21%), Positives = 180/555 (32%), Gaps = 87/555 (15%)

Query: 1501 PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGS-------------PNITVSSRSP 1547
            P TP +SS      TP    +     T   T    GS             P +  S+ + 
Sbjct: 2975 PSTPATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATT 3034

Query: 1548 PAPRFPLMTKAVTVRGHGSLPVRTTPLQPSLTASPSSRPVASPGAISRSPTSSGSHKAVL 1607
            P       T + + R   +LPV T+    S   S +  P  + G     P  + +  A +
Sbjct: 3035 PTATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLPEQTTTPMATM 3094

Query: 1608 TPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEA 1667
            +      I  +  P+ T   +  +     T A T++   P S   T  +   L+T     
Sbjct: 3095 S-----TIHPSSTPETTHTSTVLTTKATTTRA-TSSMSTPSSTPGTTWILTELTTAATTT 3148

Query: 1668 GHSQPMGSPASPQPHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFM 1727
              + P  +P+S          P      T+ T S A    T A A         A TP +
Sbjct: 3149 AATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTATTPTV 3208

Query: 1728 SLESTRPSQLLSGLPPDTSLPLAKVGTSAPVATPG---PKASVITTPLQPQATTLPAQTL 1784
                  PS   S     T+LP  +   + P AT     P +S+ T   +   TT P  T+
Sbjct: 3209 ISSRATPS---SSPGTATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTPTATM 3265

Query: 1785 SPVLP-------FTPAAMTQAHPPTHIAPPAA--GTAPGLLLGATLPT------------ 1823
            S   P        T   +T     T      A   + PG      +PT            
Sbjct: 3266 STATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSS 3325

Query: 1824 -------------SGVLPVAEGTASMVSVVPRKS------TTGKVAILSKQVSLPTSMYG 1864
                         +   P   G+    S +P  +      TT    + +  ++ P+S   
Sbjct: 3326 SPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQ 3385

Query: 1865 SAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQ 1924
            ++   P+  T AT+   T     P      T +P   +      +  T P  +   + P 
Sbjct: 3386 TSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLT------TTATTPAATSSTVTP- 3438

Query: 1925 LAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALS-------IVEGLAEALATT--TEANT 1975
             + A GT+  P     PV   T    GRS P  S            +  L TT  TE +T
Sbjct: 3439 -SSALGTTHTP-----PVPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPST 3492

Query: 1976 STTCVPIAEQDCVRH 1990
             T+  P A     +H
Sbjct: 3493 VTSHTPAATTSTTQH 3507



 Score = 65.5 bits (158), Expect = 7e-10
 Identities = 146/639 (22%), Positives = 214/639 (33%), Gaps = 92/639 (14%)

Query: 1398 VPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEE 1457
            +P+ +LG      SQ     +         +P T      LT  A  T A     T    
Sbjct: 2543 IPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATTTGATGSVAT---- 2598

Query: 1458 PVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPES-------SSLP 1510
            P  +PG   TT  + L  T +   A P+ SP +       ++   TP +       SS+P
Sbjct: 2599 PSSTPGTAHTT--KVLTTTTTGFTATPSSSPGTARTLPVWISTTTTPTTRGSTVTPSSIP 2656

Query: 1511 VALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLP-- 1568
                TPT   V     TT  T   A   + T +S +PP+    L T A T+   GS    
Sbjct: 2657 GTTHTPT---VLTTTTTTVATGSMATPSSSTQTSGTPPS----LTTTATTITATGSTTNP 2709

Query: 1569 ---VRTTPLQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQ 1625
                 TTP+ P LT + ++     P A S + T S +     TP V    + T      +
Sbjct: 2710 SSTPGTTPIPPVLTTTATT-----PAATSSTVTPSSALGTTHTPPVPNTTATTH----GR 2760

Query: 1626 AQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHP-- 1683
            + S SSP T  T   +A      +   T        T     G +Q   +PA   PHP  
Sbjct: 2761 SLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQH-STPALSSPHPSS 2819

Query: 1684 -LPSAPPRP---------------AQHTTMATRSPALPPETPAAASLSTATDGLAATPFM 1727
                +PP P               A  T   TR+  L P +P +A ++T    +   P  
Sbjct: 2820 RTTESPPSPGTTTPGHTRATSRTTATATPSKTRTSTLLPSSPTSAPITTVVT-MGCEPQC 2878

Query: 1728 S----LESTRPSQLLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQT 1783
            +    L+ + P    SG   DT   +   G +      G +      P  P       Q 
Sbjct: 2879 AWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLREL--GQV 2936

Query: 1784 LSPVLPFTPAAMTQ---------------------AHPPTHIAPPAAGTAPGLLLGATLP 1822
            +   L F      +                      H P+  A  +  T P    G T  
Sbjct: 2937 VECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAT-PSSTPGTTWI 2995

Query: 1823 TSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGSAEGGPTELTPATSHPLT 1882
             +     A  TA+  S     ST G         S  T+   ++    +  +P T+  L 
Sbjct: 2996 LTEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATTPTATSSKATSSSSPRTATTLP 3055

Query: 1883 PLVAEPEGAQAGTALPVPTSYALSRVSA----RTAPQDSMLVLLPQLAEAHGTSAGPHLA 1938
             L +    + A +  P+P S+ L          T P  +M  + P       T    H +
Sbjct: 3056 VLTSTATKSTATSFTPIP-SFTLGTTGTLPEQTTTPMATMSTIHPS-----STPETTHTS 3109

Query: 1939 AEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTST 1977
                 +ATT  +  S    S   G    L   T A T+T
Sbjct: 3110 TVLTTKATTTRATSSMSTPSSTPGTTWILTELTTAATTT 3148



 Score = 61.2 bits (147), Expect = 1e-08
 Identities = 63/260 (24%), Positives = 104/260 (40%), Gaps = 22/260 (8%)

Query: 2160 MIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQ 2219
            + V      + Q  GLCG  + + A+D T   G V       A F ++W+  ++  +   
Sbjct: 549  VFVRLDPAHQGQMCGLCGNFNQNQADDFTALSGVVEATG---AAFANTWKAQAACANARN 605

Query: 2220 TRFRPDSCATTDCSP----CLRMVS-NRTFSACHRFVPPESFCELWIRDTKYVQQP---- 2270
            +   P S +  + +     C R+   N  FS CH  + P+ F    + DT   ++     
Sbjct: 606  SFEDPCSLSVENENYARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNCERSEDCL 665

Query: 2271 CVALTVYVAMCHKFHVCI-EWRRSDYCPFL--CSSDSTYQACVTACEPPKTCQDGILGPL 2327
            C AL+ YV  C    V + +WR      ++  C     Y   V AC+P  TC+      +
Sbjct: 666  CAALSSYVHACAAKGVQLSDWRDGVCTKYMQNCPKSQRYAYVVDACQP--TCRGLSEADV 723

Query: 2328 DPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWN--SSLSGCC 2385
                  V  +GC C  GT L+   +  C+P  +C C  + G   A GE  +   ++  C 
Sbjct: 724  TCSVSFVPVDGCTCPAGTFLN--DAGACVPAQECPCY-AHGTVLAPGEVVHDEGAVCSCT 780

Query: 2386 QHQCQAPDTIVPVDLGCPSP 2405
              +       +    GC +P
Sbjct: 781  GGKLSCLGASLQKSTGCAAP 800



 Score = 59.3 bits (142), Expect = 5e-08
 Identities = 82/355 (23%), Positives = 119/355 (33%), Gaps = 53/355 (14%)

Query: 1336 CEWRYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCPTPQ-VLDEVTQRCVYLEDCVEP 1394
            CEW Y  C +PC +TCR+P      D+P +EGC P CP  Q   +E   +CV    C + 
Sbjct: 1167 CEWHYQPCGAPCLKTCRNPSGHCLVDLPGLEGCYPKCPPSQPFFNEDQMKCVAQCGCYDK 1226

Query: 1395 -------AVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTP-----AA 1442
                      VPT            G+      E        RT +++  +        A
Sbjct: 1227 DGNYYDVGARVPTAENCQSCNCTPSGIQCAHSLEACTCTYEDRTYSYQDVIYNTTDGLGA 1286

Query: 1443 PLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPH 1502
             L        T   + V  PG   TT   P   T + +P     S  S  +  S + +  
Sbjct: 1287 CLIAICGSNGTIIRKAVACPGTPATT---PFTFTTAWVP----HSTTSPALPVSTVCVRE 1339

Query: 1503 TPESSSLPVALQTPTPGMVSGAMET--------TRVTVIFAGSPNITVSSRSPPAPRFPL 1554
                SS       P PG+  G  ET         +V  + A      +  R+   P  PL
Sbjct: 1340 VCRWSSWYNG-HRPEPGLGGGDFETFENLRQRGYQVCPVLA-----DIECRAAQLPDMPL 1393

Query: 1555 --MTKAVTVRGHGSLPVRTTPLQPSLTASPSSR----------PVASPGAISRSPTSSGS 1602
              + + V       L    +   P L      R          P  +PG   +   S+ +
Sbjct: 1394 EELGQQVDCDRMRGLMCANSQQSPPLCHDYELRVLCCEYVPCGPSPAPGTSPQPSLSAST 1453

Query: 1603 HKAVLTPAVTKVISRTGVPQPTQAQSAS-------SPSTPLTVAGTAAEQVPVSP 1650
              AV TP  T    +T +      +S +       S S P+TV  +A       P
Sbjct: 1454 EPAVPTPTQTTATEKTTLWVTPSIRSTAALTSQTGSSSGPVTVTPSAPGTTTCQP 1508



 Score = 52.4 bits (124), Expect = 6e-06
 Identities = 98/478 (20%), Positives = 161/478 (33%), Gaps = 76/478 (15%)

Query: 1562 RGHGSLPVRTTPLQPSLTASPSS-----RPVASPGAISRSPTSSGSHKAVLTPAVTKVIS 1616
            RG  + P  TT L+ + T +  +     +P +SPG ++R+P +S +    L+  +T    
Sbjct: 1607 RGRATTPPPTTELETATTTTTQALFSTPQPTSSPG-LTRAPPASTTAVPTLSEGLTS--- 1662

Query: 1617 RTGVPQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSP 1676
                P+ T     ++   P T AG+    VP    +T      L    G  G  +P   P
Sbjct: 1663 ----PRYTSTLGTATTGGPTTPAGSTEPTVPGVATSTLPTRSALPGTTGSLGTWRP-SQP 1717

Query: 1677 ASPQPHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATP-----FMSLES 1731
             +  P  + ++  RP    + A++ P      P   S  + +    +TP        L +
Sbjct: 1718 PTLAPTTMATSRARPTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPRTETTMSPLTN 1777

Query: 1732 TRPSQLLSGLPP--------DTSLPLAKVG-----TSAPVATPGPKASVITTPLQPQATT 1778
            T  SQ  +   P        D   P + V      T   +   G K       ++ +A  
Sbjct: 1778 TTTSQGTTRCQPKCEWTEWFDVDFPTSGVAGGDMETFENIRAAGGKMCWAPKSIECRAEN 1837

Query: 1779 LPAQTLSPVLPFTPAAM-----------------------------TQAHPPTHIAPPAA 1809
             P  ++  V      ++                               +H P+  A  + 
Sbjct: 1838 YPEVSIDQVGQVLTCSLETGLTCKNEDQTGRFNMCFNYNVRVLCCDDYSHCPSTPATSST 1897

Query: 1810 GT---APGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGSA 1866
             T    PG     T PT+     A  T S  +      T     +L+   + PT    S+
Sbjct: 1898 ATPSSTPGTTWILTKPTTTATTTA-STGSTATPTSTLRTAPPPKVLTTTATTPT--VTSS 1954

Query: 1867 EGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTS---YALSRVSARTAPQDSMLVLLP 1923
            +  P+  +P T+  L  L +      A +  P+P+S      +R+S  T P  +M    P
Sbjct: 1955 KATPSS-SPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATP 2013

Query: 1924 QLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 1981
                   T    H +      ATT  +  S    S   G A      T   T  T  P
Sbjct: 2014 S-----STPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATP 2066



 Score = 37.7 bits (86), Expect = 0.16
 Identities = 25/83 (30%), Positives = 32/83 (38%), Gaps = 10/83 (12%)

Query: 365  CHPRASCVDSEIACVDGC-YCPNG----LIFEDGGCVAPAECP---CEFHGTLYPPGSVV 416
            C P   CV +   C      CP G       E+G C     C    C ++GT Y  G+  
Sbjct: 5480 CCPETVCVCNTTTCPQSLPVCPPGQESICTQEEGDCCPTFRCRPQLCSYNGTFYGVGATF 5539

Query: 417  KE--DCNTCTCTSGKWECSTAVC 437
                 C+ CTC SG  +  T  C
Sbjct: 5540 PGALPCHMCTCLSGDTQDPTVQC 5562



 Score = 35.4 bits (80), Expect = 0.81
 Identities = 20/57 (35%), Positives = 30/57 (52%), Gaps = 6/57 (10%)

Query: 1339 RYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCPTPQ---VLDEVTQR-CVYLEDC 1391
            ++  C SPC  TC +P+ A   +   V+GC   CP  +   VLD++T   C+ L  C
Sbjct: 334  QHQECGSPCTDTCSNPQRAQLCEDHCVDGC--FCPPGRSCTVLDDITHSGCLPLGQC 388


>gi|161019170 mucin 5AC [Homo sapiens]
          Length = 6207

 Score =  570 bits (1468), Expect = e-162
 Identities = 350/1159 (30%), Positives = 547/1159 (47%), Gaps = 100/1159 (8%)

Query: 78   ICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAV 137
            +C  WG  H +TFDG  +   G  +Y          + F++Q+      GS P      V
Sbjct: 732  VCSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCRAAYEDFNVQLRRG-LVGSRP-----VV 785

Query: 138  SLFFVGEQEIHLAKE---VTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGAS 194
            +   +  Q + L      V   G R +LP+      ++Q   Y+ V  +   T  W+G  
Sbjct: 786  TRVVIKAQGLVLEASNGSVLINGQREELPYSRTGLLVEQSGDYIKVSIRLVLTFLWNGED 845

Query: 195  AVYIKMSPELLGWTHGLCGNNNADPK-DDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPT 253
            +  +++ P+    T GLCG+ N  P  ++    + +LT   ++F +  +   P +   P 
Sbjct: 846  SALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLTP--LQFGNLQKLDGPTEQC-PD 902

Query: 254  TSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVA 313
               LP   C  +     +G+  +   LL P F  CHA V    + A+C  DLC+      
Sbjct: 903  PLPLPAGNCTDE-----EGICHR--TLLGPAFAECHALVDSTAYLAACAQDLCRCP---T 952

Query: 314  TWCRALAEYARACAQAGRPLQGWRTQL---RQCTVHCKEKAFTYNECIACCPASCHPRAS 370
              C    EY+R CA AG   + WR      R C ++ +     + EC + C  +C     
Sbjct: 953  CPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQ-----HQECGSPCTDTCSNPQR 1007

Query: 371  CVDSEIACVDGCYCPNG---LIFED---GGCVAPAECPCEFHGTLYPPGSVVKEDCNTCT 424
                E  CVDGC+CP G    + +D    GC+   +CPC   G  Y PG+     C++CT
Sbjct: 1008 AQLCEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHGGRTYSPGTSFNTTCSSCT 1067

Query: 425  CTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAP 484
            C+ G W+C    CP  CSV G  H +T+D + Y     C Y+L+K  +  +FTV  +   
Sbjct: 1068 CSGGLWQCQDLPCPGTCSVQGGAHISTYDEKLYDLHGDCSYVLSKKCADSSFTVLAELRK 1127

Query: 485  CGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFL 544
            CGL  +  C+++V++ L       + +   G V L   Y  + P +     +   SS F+
Sbjct: 1128 CGLTDNENCLKAVTLSL-DGGDTAIRVQADGGVFLNSIYTQL-PLSAANITLFTPSSFFI 1185

Query: 545  RVRTNVGVRVLYDREGL-RLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQL 603
             V+T +G+++L     L ++++++D        GLCG FN N  DDF +  GV E+T   
Sbjct: 1186 VVQTGLGLQLLVQLVPLMQVFVRLDPAHQGQMCGLCGNFNQNQADDFTALSGVVEATGAA 1245

Query: 604  FGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLT--GEMFAPCSAFLSPVPYF 661
            F N+WK  +AC+     S  DPC + ++  +Y+   CS LT     F+ C + ++P P+ 
Sbjct: 1246 FANTWKAQAACAN-ARNSFEDPCSLSVENENYARHWCSRLTDPNSAFSRCHSIINPKPFH 1304

Query: 662  EQCRRDACRC--GQPCLCATLAHYAHLCRRHGLPV-DFRARLPACAL-SCEASKEYSPCV 717
              C  D C C   + CLCA L+ Y H C   G+ + D+R  +    + +C  S+ Y+  V
Sbjct: 1305 SNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLSDWRDGVCTKYMQNCPKSQRYAYVV 1364

Query: 718  APCGRTCQDLASPE-ACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQ 776
              C  TC+ L+  +  C V           V+GC CP  T+L+  A  CVP  +C C+  
Sbjct: 1365 DACQPTCRGLSEADVTCSVSFVP-------VDGCTCPAGTFLN-DAGACVPAQECPCYAH 1416

Query: 777  GVDYPPGDSDIPSLGHCHCKDGVMSC--DSRAPAAACPAGQVFVNCSDLHTDLELSRERT 834
            G    PG+        C C  G +SC   S   +  C A  V+++CS+       +    
Sbjct: 1417 GTVLAPGEVVHDEGAVCSCTGGKLSCLGASLQKSTGCAAPMVYLDCSNSSAG---TPGAE 1473

Query: 835  CEQQLLNLSVSARGP-CLSGCACPQGLLRHGD-ACFLPEECPCTWKGKEYFPGDQVMSPC 892
            C +    L V      C+SGC CP GL+  G   C   E+CPC      Y PG+ +   C
Sbjct: 1474 CLRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKPGETIRVDC 1533

Query: 893  HTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVK-----STSDVS 947
            +TC C+   ++C+   C  TC AYGD H+ TFDG  + F G+C+  L +     +T+  +
Sbjct: 1534 NTCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNTTHGT 1593

Query: 948  FSVIVENVNCYSSGMICRK----FISINVGNSLIVFDDDSGNPSP-ESFLDDKQEV---- 998
            F ++ EN+ C ++G  C K    F+ +    ++   D  +  P+P E+ +  +Q +    
Sbjct: 1594 FRIVTENIPCGTTGTTCSKAIKLFVEVRTAPAVSTPDPAANEPAPREASVGFRQRLPPLQ 1653

Query: 999  ---------------------HTWRVGFFTLVHFPQEH-ITLLWDQRTTVHVQAGPQWQG 1036
                                   +++ +  +    + H + + WD++T+V ++    ++G
Sbjct: 1654 SYELILQEGTFKAVARGPGGDPPYKIRYMGIFLVIETHGMAVSWDRKTSVFIRLHQDYKG 1713

Query: 1037 QLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSW-AAVECPDTLDPRDMCVLNPLREPF 1095
            ++ GLCGNFD   IN+  T     + +  EFG+SW  +  CPD L P+D C  NP R+ +
Sbjct: 1714 RVCGLCGNFDDNAINDFATRSRSVVGDALEFGNSWKLSPSCPDALAPKDPCTANPFRKSW 1773

Query: 1096 AKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHG 1155
            A+K+CSIL    F  C   VD T +Y  C+ D C C  GGDCECFC +V+AYA  C   G
Sbjct: 1774 AQKQCSILHGPTFAACRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACHDAG 1833

Query: 1156 VAVDWRTPRLCPYDCDFFN 1174
            + V WRTP  CP  CDF+N
Sbjct: 1834 LCVSWRTPDTCPLFCDFYN 1852



 Score =  264 bits (675), Expect = 8e-70
 Identities = 180/565 (31%), Positives = 268/565 (47%), Gaps = 29/565 (5%)

Query: 78  ICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAV 137
           +C  WG  H +TFDG  +   G  +Y          + F+IQ+    +  S+  T SR  
Sbjct: 80  VCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQE--SAAPTLSRV- 136

Query: 138 SLFFVGEQEIHLAK-EVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAV 196
            L  V    I L K  V   G  V LP       +QQ + Y  V  +    L W+   ++
Sbjct: 137 -LMKVDGVVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKVEARLGLVLMWNHDDSL 195

Query: 197 YIKMSPELLGWTHGLCGNNNADPK-DDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTS 255
            +++  +    T GLCG+ N  P   +L++ + KLT   +EF +    Q  + P      
Sbjct: 196 LLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTP--MEFGNL---QKMDDPTEQCQD 250

Query: 256 SLPRPPCLQQNPGTMQGVYEQCEALLRPP-FDACHAYVSPLPFTASCTSDLC--QSMGDV 312
            +P PP   +N  T  G+   CE LL    F  C A V    +  +C  DLC  +    +
Sbjct: 251 PVPEPP---RNCSTGFGI---CEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLL 304

Query: 313 ATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCV 372
           +  C  LAEY+R C  AG   Q WR     C   C      Y+EC + C  +C  +    
Sbjct: 305 SCVCHTLAEYSRQCTHAGGLPQDWRGP-DFCPQKCPNN-MQYHECRSPCADTCSNQEHSR 362

Query: 373 DSEIACVDGCYCPNGLIFED---GGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGK 429
             E  CV GC+CP G + +D    GCV  ++C C ++G  Y PG+    DC  CTC+ G+
Sbjct: 363 ACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYSTDCTNCTCSGGR 422

Query: 430 WECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQ 489
           W C    CP  CSV G  HF+TFDG++YT    C Y+L K   S  FTV  +   CGL  
Sbjct: 423 WSCQEVPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCGLTD 482

Query: 490 DGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTN 549
              C++SV++ L  D  + V + +A   +  +Q     P +     I R S+ F+  +T+
Sbjct: 483 SETCLKSVTLSL--DGAQTVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTS 540

Query: 550 VGVRV-LYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSW 608
           +G+++ L     ++L++Q+  +    T GLCG FN    DDF +  GV E+T   F N++
Sbjct: 541 LGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTF 600

Query: 609 KTLSACSPLVSGSPLDPCDVHLQAA 633
           KT +AC P +  S  DPC + ++ A
Sbjct: 601 KTQAAC-PNIRNSFEDPCSLSVENA 624



 Score =  231 bits (589), Expect = 8e-60
 Identities = 152/500 (30%), Positives = 233/500 (46%), Gaps = 68/500 (13%)

Query: 361  CPASCHPR-ASCVDSEIACVDGCYCPNGLIFE-DGGCVAPAECPCEFHGTLYPPGSVVKE 418
            C  SCH     C  +   CV GC CP GL+ +  GGC+A  +CPC  +   Y PG  ++ 
Sbjct: 1474 CLRSCHTLDVGCFSTH--CVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKPGETIRV 1531

Query: 419  DCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAK-----SRSS 473
            DCNTCTC + +WECS  +C   C   GD HF TFDG RY+F  +C+YILA+     + + 
Sbjct: 1532 DCNTCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNTTH 1591

Query: 474  GTFTVTLQNAPCGLNQDGAC--------VQSVSVILHQDP--------------RRQVTL 511
            GTF +  +N PCG               V++   +   DP              R+++  
Sbjct: 1592 GTFRIVTENIPCGTTGTTCSKAIKLFVEVRTAPAVSTPDPAANEPAPREASVGFRQRLPP 1651

Query: 512  TQAGDVLLFD-QYKIIP--PYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVD 568
             Q+ +++L +  +K +   P  D  ++IR +  +FL + T+ G+ V +DR+   +++++ 
Sbjct: 1652 LQSYELILQEGTFKAVARGPGGDPPYKIRYM-GIFLVIETH-GMAVSWDRK-TSVFIRLH 1708

Query: 569  QRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDV 628
            Q +     GLCG F+ N  +DF +           FGNSWK   +C   +  +P DPC  
Sbjct: 1709 QDYKGRVCGLCGNFDDNAINDFATRSRSVVGDALEFGNSWKLSPSCPDAL--APKDPCTA 1766

Query: 629  HLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQ----PCLCATLAHYA 684
            +    S++ + CS+L G  FA C + +    Y+E C  DAC C       C C  +A YA
Sbjct: 1767 NPFRKSWAQKQCSILHGPTFAACRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYA 1826

Query: 685  HLCRRHGLPVDFRARLPACALSCE-------ASKEYSPCVAPCGRTCQDLASPEACGVDG 737
              C   GL V +R     C L C+           Y PC APC +TC++ +      + G
Sbjct: 1827 QACHDAGLCVSWRTP-DTCPLFCDFYNPHGGCEWHYQPCGAPCLKTCRNPSGHCLVDLPG 1885

Query: 738  GDDLSRDECVEGC--ACPP-DTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGH-- 792
                     +EGC   CPP   + +     CV   QC C+ +  +Y    + +P+  +  
Sbjct: 1886 ---------LEGCYPKCPPSQPFFNEDQMKCVA--QCGCYDKDGNYYDVGARVPTAENCQ 1934

Query: 793  -CHCKDGVMSCDSRAPAAAC 811
             C+C    + C     A  C
Sbjct: 1935 SCNCTPSGIQCAHSLEACTC 1954



 Score =  149 bits (376), Expect = 4e-35
 Identities = 107/380 (28%), Positives = 163/380 (42%), Gaps = 35/380 (9%)

Query: 441 CSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSG--TFTVTLQNAPCGLNQDGACVQSVS 498
           CS  G  H+ TFDG  + FP  C Y+ ++   +    F + L+ +     Q+ A      
Sbjct: 81  CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRS-----QESAAPTLSR 135

Query: 499 VILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDR 558
           V++  D    V +      +L + + ++ P++     I++ SS + +V   +G+ ++++ 
Sbjct: 136 VLMKVDG---VVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSS-YTKVEARLGLVLMWNH 191

Query: 559 EGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLV 618
           +   L L++D ++   T GLCG FNG      L      + TP  FGN  K         
Sbjct: 192 DD-SLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNT-KLTPMEFGNLQKMDDPTEQCQ 249

Query: 619 SGSPLDPCDVHLQAASYSVQACS-VLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQ---- 673
              P  P     +  S     C  +L G++F+ C A +    Y E CR+D C C      
Sbjct: 250 DPVPEPP-----RNCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLL 304

Query: 674 PCLCATLAHYAHLC-RRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEA 732
            C+C TLA Y+  C    GLP D+R     C   C  + +Y  C +PC  TC +     A
Sbjct: 305 SCVCHTLAEYSRQCTHAGGLPQDWRGP-DFCPQKCPNNMQYHECRSPCADTCSNQEHSRA 363

Query: 733 CGVDGGDDLSRDECVEGCACPPDTYLDTQADL-CVPRNQCSCHFQGVDYPPGDSDIPSLG 791
           C          D CV GC CP  T LD      CVP ++C+C + G  Y PG +      
Sbjct: 364 C---------EDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYSTDCT 414

Query: 792 HCHCKDGVMSCDSRAPAAAC 811
           +C C  G  SC        C
Sbjct: 415 NCTCSGGRWSCQEVPCPGTC 434



 Score =  144 bits (363), Expect = 1e-33
 Identities = 127/443 (28%), Positives = 162/443 (36%), Gaps = 83/443 (18%)

Query: 2174 GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSC------ 2227
            G CG C  +  +D   +DG+     +D A    +W VP S         R D C      
Sbjct: 5556 GQCGTCTNNQRDDCLQRDGTTAASCKDMAK---TWLVPDS---------RKDGCWAPTGT 5603

Query: 2228 --------------ATTDCSP---CLRMVSNRTFSACHRFVPPESFCELWIRD--TKYVQ 2268
                            T C P   C  M+S + F+ CH  VPP  F    I D     ++
Sbjct: 5604 PPTASPAAPVSSTPTPTPCPPQPLCDLMLS-QVFAECHNLVPPGPFFNACISDHCRGRLE 5662

Query: 2269 QPCVALTVYVAMCHKFHVCIEWRRSD--YCPFLCSSDSTYQACVTACEPPKTCQDGILGP 2326
             PC +L  Y  +C    VC +WR +    C   C     Y+ C      P TC      P
Sbjct: 5663 VPCQSLEAYAELCRARGVCSDWRGATGGLCDLTCPPTKVYKPCGPI--QPATCNSRNQSP 5720

Query: 2327 LDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQ 2386
                  + + EGC C E  IL   H  +C+    C C    G P+  GE W S+   C  
Sbjct: 5721 ----QLEGMAEGCFCPEDQILFNAHMGICVQA--CPCVGPDGFPKFPGERWVSNCQSCVC 5774

Query: 2387 HQCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLP-TKDPCCLGTVCVCNQTLCEGLAPT 2445
             +        P+       +P  C R G V +  P  ++PCC  TVCVCN T C    P 
Sbjct: 5775 DEGSVSVQCKPLPCDAQG-QPPPCNRPGFVTVTRPRAENPCCPETVCVCNTTTCPQSLPV 5833

Query: 2446 CRPGHRLLTHFQEDSCCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCAC 2505
            C PG   +   +E  CCP++ C   P LC      +         G L    CT   C  
Sbjct: 5834 CPPGQESICTQEEGDCCPTFRCR--PQLCSYN--GTFYGVGATFPGALPCHMCT---CLS 5886

Query: 2506 GDCPDSIPECQEGEALTVHRNTTELCCP--------LYQCVCENFRCPQVQC----GLGT 2553
            GD  D   +CQE        NTT   CP          QC  E   C Q  C    G   
Sbjct: 5887 GDTQDPTVQCQEDAC----NNTT---CPQGFEYKRVAGQCCGE---CVQTACLTPDGQPV 5936

Query: 2554 ALVEVW---SPDRCCPYKSCECD 2573
             L E W     D C  Y  CE +
Sbjct: 5937 QLNETWVNSHVDNCTVY-LCEAE 5958



 Score =  134 bits (337), Expect = 1e-30
 Identities = 147/579 (25%), Positives = 220/579 (37%), Gaps = 108/579 (18%)

Query: 402  PCEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTAVCPAE--CSVTGDIHFTTFDGRRYTF 459
            PC+FH            +C  C C  G+      + P    CS+ G  H++TFDG  YTF
Sbjct: 5386 PCDFH-----------YECE-CECVGGR-----GITPGAGICSMWGGSHYSTFDGTSYTF 5428

Query: 460  PATCQYILAKSRSS--GTFTVTLQNAPCGLNQDGA-----CVQSVSV-ILHQDPRRQVTL 511
               C Y+L +   +  G  ++ L N  C  +   A     C +++S+     D    VT+
Sbjct: 5429 RGNCTYVLMREIHARFGNLSLYLDNHYCTASATAAAAAARCPRALSIHYKSMDIVLTVTM 5488

Query: 512  TQAGD--VLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTN-VGVRVLYDREGLRLYLQVD 568
                +  ++LFDQ  +   ++ +   +  L +  +RV    +GV V ++ +  +  L   
Sbjct: 5489 VHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMRVDIPALGVSVTFNGQVFQARLPYS 5548

Query: 569  QRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSW-----------------KTL 611
              +  +T G CGT   N +DD L   G   ++ +    +W                  T 
Sbjct: 5549 L-FHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTWLVPDSRKDGCWAPTGTPPTA 5607

Query: 612  SACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRC 671
            S  +P+ S     PC             C ++  ++FA C   + P P+F  C  D CR 
Sbjct: 5608 SPAAPVSSTPTPTPCPPQ--------PLCDLMLSQVFAECHNLVPPGPFFNACISDHCRG 5659

Query: 672  GQPCLCATLAHYAHLCRRHGLPVDFR-ARLPACALSCEASKEYSPCVAPCGRTCQDL-AS 729
                 C +L  YA LCR  G+  D+R A    C L+C  +K Y PC      TC     S
Sbjct: 5660 RLEVPCQSLEAYAELCRARGVCSDWRGATGGLCDLTCPPTKVYKPCGPIQPATCNSRNQS 5719

Query: 730  PEACGVDGGDDLSRDECVEGCACPPDTYL-DTQADLCVPRNQCSC-HFQGVDYPPGDSDI 787
            P+  G+            EGC CP D  L +    +CV    C C    G    PG+  +
Sbjct: 5720 PQLEGM-----------AEGCFCPEDQILFNAHMGICV--QACPCVGPDGFPKFPGERWV 5766

Query: 788  PSLGHCHCKDGVMS-------CDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLL 840
             +   C C +G +S       CD++     C       N     T      E  C  + +
Sbjct: 5767 SNCQSCVCDEGSVSVQCKPLPCDAQGQPPPC-------NRPGFVTVTRPRAENPCCPETV 5819

Query: 841  NLSVSARGPCLSGCACPQG-----LLRHGDAC--FLPEECPCTWKGKEY-----FPGDQV 888
             +  +   P  S   CP G         GD C  F      C++ G  Y     FPG   
Sbjct: 5820 CVCNTTTCP-QSLPVCPPGQESICTQEEGDCCPTFRCRPQLCSYNGTFYGVGATFPG--- 5875

Query: 889  MSPCHTCVCQRG-----SFQCTLHPCASTCTAYGDRHYR 922
              PCH C C  G     + QC    C +T    G  + R
Sbjct: 5876 ALPCHMCTCLSGDTQDPTVQCQEDACNNTTCPQGFEYKR 5914



 Score =  133 bits (334), Expect = 3e-30
 Identities = 121/444 (27%), Positives = 183/444 (41%), Gaps = 74/444 (16%)

Query: 79   CRAWGQHHVETFDGLYYYLSGKGSYTLV----GRHEPEGQSFSIQVHNDPQCGSSPYTCS 134
            C A+G  H  TFDG  Y   G   Y L     G +   G +F I   N P CG++  TCS
Sbjct: 1554 CVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNTTHG-TFRIVTENIP-CGTTGTTCS 1611

Query: 135  RAVSLFFVGEQEIHLAKEVTHG--------------GMRVQLPHVMGSARLQQ------- 173
            +A+ LF     E+  A  V+                G R +LP +     + Q       
Sbjct: 1612 KAIKLFV----EVRTAPAVSTPDPAANEPAPREASVGFRQRLPPLQSYELILQEGTFKAV 1667

Query: 174  -------------LAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPK 220
                           G  +V       ++WD  ++V+I++  +  G   GLCGN + +  
Sbjct: 1668 ARGPGGDPPYKIRYMGIFLVIETHGMAVSWDRKTSVFIRLHQDYKGRVCGLCGNFDDNAI 1727

Query: 221  DDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEAL 280
            +D  T S  +  D +EF +SW+       P    +  P+ PC   NP       +QC  L
Sbjct: 1728 NDFATRSRSVVGDALEFGNSWK-----LSPSCPDALAPKDPC-TANPFRKSWAQKQCSIL 1781

Query: 281  LRPPFDACHAYVSPLPFTASCTSD--LCQSMGDVATWCRALAEYARACAQAGRPLQGWRT 338
              P F AC + V    +  +C +D   C S GD   +C A+A YA+AC  AG  +  WRT
Sbjct: 1782 HGPTFAACRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACHDAGLCV-SWRT 1840

Query: 339  QLRQCTVHCK------EKAFTYNECIACCPASC-HPRASCVDSEIACVDGCY--C-PNGL 388
                C + C          + Y  C A C  +C +P   C+  ++  ++GCY  C P+  
Sbjct: 1841 P-DTCPLFCDFYNPHGGCEWHYQPCGAPCLKTCRNPSGHCL-VDLPGLEGCYPKCPPSQP 1898

Query: 389  IFEDGGCVAPAECPC-EFHGTLYPPGSVV--KEDCNTCTCTSGKWECSTAVCPAECSVTG 445
             F +      A+C C +  G  Y  G+ V   E+C +C CT    +C+ ++    C+   
Sbjct: 1899 FFNEDQMKCVAQCGCYDKDGNYYDVGARVPTAENCQSCNCTPSGIQCAHSLEACTCTYED 1958

Query: 446  ------DIHFTTFDGRRYTFPATC 463
                  D+ + T DG      A C
Sbjct: 1959 RTYSYQDVIYNTTDGLGACLIAIC 1982



 Score =  101 bits (251), Expect = 1e-20
 Identities = 103/408 (25%), Positives = 156/408 (38%), Gaps = 67/408 (16%)

Query: 724  CQDLAS--PEACGVDGG--DDLSRDECVEGCACPPD--TYLDT-QADLCVPRN----QCS 772
            CQD     P  C    G  ++L   +   GC    D  +YL+  + DLC   +     C 
Sbjct: 248  CQDPVPEPPRNCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLLSCV 307

Query: 773  CHFQGVDYP---------PGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDL 823
            CH    +Y          P D   P      C + +   + R+P            C+D 
Sbjct: 308  CHTLA-EYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSP------------CADT 354

Query: 824  HTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHG---DACFLPEECPCTWKGK 880
             ++ E SR   CE             C++GC CP+G +        C    +C C + G 
Sbjct: 355  CSNQEHSR--ACEDH-----------CVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGA 401

Query: 881  EYFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLV 940
             Y PG    + C  C C  G + C   PC  TC+  G  H+ TFDG  +   G C   L 
Sbjct: 402  AYAPGATYSTDCTNCTCSGGRWSCQEVPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLT 461

Query: 941  KSTSDVSFSVIVENVNC-YSSGMICRKFISINV-GNSLIVFDDDSGNPSPESFLD----- 993
            K     +F+V+ E   C  +    C K +++++ G   +V    SG    E FL+     
Sbjct: 462  KPCDSSAFTVLAELRRCGLTDSETCLKSVTLSLDGAQTVVVIKASG----EVFLNQIYTQ 517

Query: 994  ---DKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVH--VQAGPQWQGQLAGLCGNFDLK 1048
                   V  +R   F ++      + L      T+   +Q  P+ +GQ  GLCGNF+  
Sbjct: 518  LPISAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSI 577

Query: 1049 TINEMRTPEN-LELTNPQEFGSSWAAVECPDTLDP-RDMCVLNPLREP 1094
              ++ RT    +E T    F +      CP+  +   D C L+    P
Sbjct: 578  QADDFRTLSGVVEATAAAFFNTFKTQAACPNIRNSFEDPCSLSVENAP 625



 Score = 91.7 bits (226), Expect = 1e-17
 Identities = 100/398 (25%), Positives = 147/398 (36%), Gaps = 50/398 (12%)

Query: 78   ICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHN-----DPQCGSSPYT 132
            IC  WG  H  TFDG  Y   G  +Y L+        + S+ + N          ++   
Sbjct: 5409 ICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTASATAAAAAAR 5468

Query: 133  CSRAVSLFFVGEQEIHLAKEVTHG---GMRV--QLPHVMGSAR---LQQLAGYVIVRHQ- 183
            C RA+S+ +    +I L   + HG   G+ +  Q+P   G ++   L  + G   +R   
Sbjct: 5469 CPRALSIHYKS-MDIVLTVTMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMRVDI 5527

Query: 184  SAFTLAWDGASAVYIKMSPELL--GWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSW 241
             A  ++      V+    P  L    T G CG    + +DD +   G       +   +W
Sbjct: 5528 PALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTW 5587

Query: 242  -------------QEQAPNQPPGPTTSSLPRP-PCLQQNPGTMQGVYEQCEALLRPPFDA 287
                             P   P    SS P P PC  Q           C+ +L   F  
Sbjct: 5588 LVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQ---------PLCDLMLSQVFAE 5638

Query: 288  CHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQL-RQCTVH 346
            CH  V P PF  +C SD C+  G +   C++L  YA  C   G     WR      C + 
Sbjct: 5639 CHNLVPPGPFFNACISDHCR--GRLEVPCQSLEAYAELCRARG-VCSDWRGATGGLCDLT 5695

Query: 347  CKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCP-NGLIFEDGGCVAPAECPCEF 405
            C      Y  C    PA+C+ R      E    +GC+CP + ++F     +    CPC  
Sbjct: 5696 CPPTK-VYKPCGPIQPATCNSRNQSPQLE-GMAEGCFCPEDQILFNAHMGICVQACPCVG 5753

Query: 406  -HGTLYPPGSVVKEDCNTCTCTSG--KWECSTAVCPAE 440
              G    PG     +C +C C  G    +C    C A+
Sbjct: 5754 PDGFPKFPGERWVSNCQSCVCDEGSVSVQCKPLPCDAQ 5791



 Score = 89.0 bits (219), Expect = 6e-17
 Identities = 138/521 (26%), Positives = 192/521 (36%), Gaps = 74/521 (14%)

Query: 1407 TLPPSQGLPTPSD-----EEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVVS 1461
            T PP + L +P+           S  SPRT T  P LT  A  +TA     + T  P  +
Sbjct: 4748 TAPPPKVLTSPATTPTATSSKATSSSSPRTATTLPVLTSTATKSTA----TSVTPIPSST 4803

Query: 1462 PGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMV 1521
             G T T  +Q     A+     P+ +P +   T+++L    T   ++   +  + TPG  
Sbjct: 4804 LGTTGTLPEQTTTPVATMSTIHPSSTPETTH-TSTVLTTKATTTRATSSTSTPSSTPGTT 4862

Query: 1522 SGAME-TTRVTVIFAGSPNITVSSRSPPAPRF---PLMTKAVTVRGHGSLPV-RTTP--- 1573
                E TT  T   A  P  T S  S P   +    L T A T    GS     +TP   
Sbjct: 4863 WILTELTTAATTTAATGPTATPS--STPGTTWILTELTTTATTTASTGSTATPSSTPGTT 4920

Query: 1574 ---LQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSAS 1630
                +PS TA+ +  P  S    S +  ++G+     T     V S    P  +   + +
Sbjct: 4921 WILTEPSTTATVTV-PTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGTATA 4979

Query: 1631 SP---STPLTVAGTAAEQVPVSPLATRSLEI-VLSTEKGEAGHSQPMGSPASPQPHPLPS 1686
             P   ST  T   T+   +P S L T    +   +T       + P  +P +     + +
Sbjct: 4980 LPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLT 5039

Query: 1687 APPRPAQHTTMATRSPALPPETPAAASL----STATDGLAATPFMSLESTRPSQLLSGLP 1742
            A       TT AT S A P  TP  A      +T T G  ATP  S              
Sbjct: 5040 A----TATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSS-------------- 5081

Query: 1743 PDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHPPT 1802
            P T+L       + P  TP    S I T   P+ T       S VL  T A MT+A   T
Sbjct: 5082 PGTAL-------TPPTTTPMSTMSTIHTSSTPETT-----HTSTVLT-TTATMTRATNST 5128

Query: 1803 HIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSM 1862
                      P   LG T   + +   A  TA+  S     ST G   IL++  ++ T M
Sbjct: 5129 --------ATPSSTLGTTRILTELTTTATTTAATGSTATLSSTPGTTWILTEPSTIATVM 5180

Query: 1863 YGSAEGGPTELTPATSHPLTPLVAEPEGAQ-AGTALPVPTS 1902
              +        T  T+H  TP V          TA  VP+S
Sbjct: 5181 VPTGSTATASSTLGTAH--TPKVVTTMATMPTATASTVPSS 5219



 Score = 84.7 bits (208), Expect = 1e-15
 Identities = 95/386 (24%), Positives = 147/386 (38%), Gaps = 60/386 (15%)

Query: 2482 CRQDQILITGRLGDSCCTSYFCACGDCPDSIPE------CQEGEALTVHRNTTELCCPLY 2535
            C +DQIL    +G   C    C C   PD  P+          ++      +  + C   
Sbjct: 5731 CPEDQILFNAHMG--ICVQA-CPCVG-PDGFPKFPGERWVSNCQSCVCDEGSVSVQCKPL 5786

Query: 2536 QCVCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIP--VPRCHLWEKSQLDEE 2593
             C  +    P  + G  T +    + + CCP   C C+  T P  +P C   ++S   +E
Sbjct: 5787 PCDAQGQPPPCNRPGFVT-VTRPRAENPCCPETVCVCNTTTCPQSLPVCPPGQESICTQE 5845

Query: 2594 FMHSVENVCGCAKYECVKAPVCLSR----ELGVMQPGQTVVELSADGVCHTSRCTT--VL 2647
                 E  C C  + C +  +C        +G   PG           CH   C +    
Sbjct: 5846 -----EGDC-CPTFRC-RPQLCSYNGTFYGVGATFPGAL--------PCHMCTCLSGDTQ 5890

Query: 2648 DPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTTSLFLPGA 2707
            DP     +    +  C       Q +E+ R    CCG C   +CL   P+G         
Sbjct: 5891 DPTVQCQEDACNNTTCP------QGFEYKRVAGQCCGECVQTACL--TPDGQPVQL--NE 5940

Query: 2708 SW----IADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTCKED 2763
            +W    + +C  + C +     +L   P SCP ++        GS+  +  GCC +C+ED
Sbjct: 5941 TWVNSHVDNCTVYLCEAEGGVHLLTPQPASCPDVSSCR-----GSLRKT--GCCYSCEED 5993

Query: 2764 GRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVGLQR 2823
              SC +V I  TI  ++    T VN+  C+G CP AS Y+         C CC+E  +  
Sbjct: 5994 --SC-QVRINTTILWHQ-GCETEVNITFCEGSCPGASKYSAEAQAMQHQCTCCQERRVHE 6049

Query: 2824 RSVQLFCATNATWVPYTVQEPTDCAC 2849
             +V L C  N + + +T        C
Sbjct: 6050 ETVPLHC-PNGSAILHTYTHAVQVLC 6074



 Score = 83.2 bits (204), Expect = 3e-15
 Identities = 133/580 (22%), Positives = 205/580 (35%), Gaps = 65/580 (11%)

Query: 1429 PRTP-THRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTES 1487
            P TP T   A+  + P TT +   +T T     S G T T    P      ++   P  +
Sbjct: 4702 PSTPATSSTAMPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTAPPPKVLTSPATT 4761

Query: 1488 PASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGS-PNITVSSRS 1546
            P +    A+  + P T  +++LPV   T T    +        T+   G+ P  T +  +
Sbjct: 4762 PTATSSKATSSSSPRT--ATTLPVLTSTATKSTATSVTPIPSSTLGTTGTLPEQTTTPVA 4819

Query: 1547 PPAPRFPLMTKAVTVRGHGSLPVRTTPLQPSLTASPSSRP----------VASPGAISRS 1596
              +   P  T   T          TT    S T++PSS P           A+    +  
Sbjct: 4820 TMSTIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATG 4879

Query: 1597 PTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSL 1656
            PT++ S     TP  T +++       T A S  S +TP +  GT    +   P  T ++
Sbjct: 4880 PTATPSS----TPGTTWILTELTTTATTTA-STGSTATPSSTPGTT--WILTEPSTTATV 4932

Query: 1657 EIVLSTEKGEAGHSQPMGSPASPQPHPLP---SAPPRPAQHTTMATRSPAL--PPETPAA 1711
             +   +    +      G+P        P   S+   P+     AT  PAL     TP A
Sbjct: 4933 TVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTA 4992

Query: 1712 ASLSTATDGLAATPFMSL-ESTRPSQLLSGLPPDTSLPLAKVGT--SAPVATPGPKASVI 1768
             S +        T +  L ++T P+  +S   P ++       T  +A   T G   SV 
Sbjct: 4993 TSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTATATTTGATGSVA 5052

Query: 1769 T---TPLQPQATTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAA---GTAPGLLLGATLP 1822
            T   TP     T +P  T +    FT  A   + P T + PP      T   +   +T  
Sbjct: 5053 TPSSTPGTAHTTKVPTTTTTG---FT--ATPSSSPGTALTPPTTTPMSTMSTIHTSSTPE 5107

Query: 1823 TSGVLPVAEGTASMV----SVVPRKSTTGKVAILSKQVSLPTSMYGSAEGGPTELTPATS 1878
            T+    V   TA+M     S     ST G   IL++  +  T+   +        TP T+
Sbjct: 5108 TTHTSTVLTTTATMTRATNSTATPSSTLGTTRILTELTTTATTTAATGSTATLSSTPGTT 5167

Query: 1879 HPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLAEAHGTSAGPHLA 1938
              LT    EP                 S ++    P  S       L  AH       +A
Sbjct: 5168 WILT----EP-----------------STIATVMVPTGSTATASSTLGTAHTPKVVTTMA 5206

Query: 1939 AEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTT 1978
              P   A+T PS  +         L  +L T + +  S++
Sbjct: 5207 TMPTATASTVPSSSTVGTTRTPAVLPSSLPTFSVSTVSSS 5246



 Score = 80.9 bits (198), Expect = 2e-14
 Identities = 136/523 (26%), Positives = 192/523 (36%), Gaps = 84/523 (16%)

Query: 1501 PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGS-------------PNITVSSRSP 1547
            P TP +SS  +   TP    +   + TT  T    GS             P +  S  + 
Sbjct: 4702 PSTPATSSTAMPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTAPPPKVLTSPATT 4761

Query: 1548 PAPRFPLMTKAVTVRGHGSLPVRTT----PLQPSLTASPSS-------------RPVASP 1590
            P       T + + R   +LPV T+        S+T  PSS              PVA+ 
Sbjct: 4762 PTATSSKATSSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGTLPEQTTTPVATM 4821

Query: 1591 GAISRSPTSSGSH-KAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAG--TAAEQVP 1647
              I  S T   +H   VLT   T   + +    P+     +   T LT A   TAA    
Sbjct: 4822 STIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATGPT 4881

Query: 1648 VSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPRPAQHTTMATRSPALPPE 1707
             +P +T     +L+     A  +   GS A+P     P       + +T AT    +P  
Sbjct: 4882 ATPSSTPGTTWILTELTTTATTTASTGSTATPS--STPGTTWILTEPSTTAT--VTVPTG 4937

Query: 1708 TPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPD------TSLPLAKVGTSAPVATP 1761
            + A AS + AT   A TP +S  +T P+   S   P       T+LP  +   + P AT 
Sbjct: 4938 STATASSTQAT---AGTPHVSTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATS 4994

Query: 1762 G---PKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLG 1818
                P +S+ TT  +   TT P  T+S   P    + T     T     A  T  G    
Sbjct: 4995 FTAIPSSSLGTTWTRLSQTTTPTATMSTATP----SSTPETVHTSTVLTATATTTGATGS 5050

Query: 1819 ATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGSAEGGPTELTPATS 1878
               P+S       GTA   + VP  +TTG  A        P+S  G+A   PT  TP ++
Sbjct: 5051 VATPSS-----TPGTAH-TTKVPTTTTTGFTA-------TPSSSPGTALTPPT-TTPMST 5096

Query: 1879 HPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLAEAHGTSAGPHLA 1938
                   + PE     T L   T+  ++R +  TA   S L          GT+    + 
Sbjct: 5097 MSTIHTSSTPETTHTSTVL--TTTATMTRATNSTATPSSTL----------GTT---RIL 5141

Query: 1939 AEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 1981
             E    ATT  +  S   LS   G    L  T  +  +T  VP
Sbjct: 5142 TELTTTATTTAATGSTATLSSTPGTTWIL--TEPSTIATVMVP 5182



 Score = 79.3 bits (194), Expect = 5e-14
 Identities = 69/285 (24%), Positives = 110/285 (38%), Gaps = 18/285 (6%)

Query: 2107 VTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASK 2166
            V I      V V+  PV  P S+ G  I+ +     +     + + W H   L++   +K
Sbjct: 143  VVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKVEARLGLVLMWNHDDSLLLELDTK 202

Query: 2167 TSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDS 2226
             +  +  GLCG  +G       L   + +     P  F +  ++             P  
Sbjct: 203  YAN-KTCGLCGDFNGMPVVSELLSHNTKL----TPMEFGNLQKMDDPTEQCQDPVPEPPR 257

Query: 2227 CATTDCSPCLRMVSNRTFSACHRFVPPESFCEL------WIRDTKYVQQPCVALTVYVAM 2280
              +T    C  ++  + FS C   V   S+ E       +  DT  +   C  L  Y   
Sbjct: 258  NCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLLSCVCHTLAEYSRQ 317

Query: 2281 C-HKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGC 2339
            C H   +  +WR  D+CP  C ++  Y  C + C    TC +        +HC     GC
Sbjct: 318  CTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCAD--TCSNQEHSRACEDHCVA---GC 372

Query: 2340 VCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGC 2384
             C EGT+L       C+P +KCAC  + G   A G T+++  + C
Sbjct: 373  FCPEGTVLDDIGQTGCVPVSKCACVYN-GAAYAPGATYSTDCTNC 416



 Score = 79.3 bits (194), Expect = 5e-14
 Identities = 156/681 (22%), Positives = 228/681 (33%), Gaps = 112/681 (16%)

Query: 1400 TEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPV------- 1452
            T A G+   P S    TP       + + P T T    +TP++   TA  PPV       
Sbjct: 4372 TRATGSVATPSS----TPGTAH---TTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTT 4424

Query: 1453 TATEEPVVSPGPTQTTLQQP--LELTASQLPAGPTESPASKGVTASLLAIPHTPE----- 1505
              T    V+P     T   P  L  T + +  G   +P+S   T+     P  P      
Sbjct: 4425 PTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTTATT 4484

Query: 1506 -----SSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITV------------------ 1542
                 S S P  ++T      SG + TT +T    G+ +                     
Sbjct: 4485 HGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHP 4544

Query: 1543 SSRSPPAPRFPLMTKAVTVRGHGSLPVRTTPLQ-PSLT-------ASPSSRPVASPGAIS 1594
            SSR+  +P  P      T  GH +   RTT    PS T       +SP+S P+ +     
Sbjct: 4545 SSRTTESPPSP----GTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTTG 4600

Query: 1595 RSPTSSGSHKAVLT-----------PAVTKVISRTGV----PQPTQAQSASSPSTPLTVA 1639
              P  + S     +              + + +  G     P   + ++ + P  PL   
Sbjct: 4601 CEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLGEL 4660

Query: 1640 GTAAEQVPVSPLATRSLEIV-------------LSTEKGEAGHSQPMGSPASPQPHPLPS 1686
            G   E      L  R+ E V                  G    +    S A P   P  +
Sbjct: 4661 GQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPGTT 4720

Query: 1687 ---APPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPS---QLLSG 1740
                       TT +T S A P  TP  A         A TP  +      S   +  + 
Sbjct: 4721 WILTELTTTATTTASTGSTATPSSTPGTAPPPKVLTSPATTPTATSSKATSSSSPRTATT 4780

Query: 1741 LPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHP 1800
            LP  TS       TS    TP P +++ TT   P+ TT P  T+S + P +    T  H 
Sbjct: 4781 LPVLTSTATKSTATSV---TPIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETT--HT 4835

Query: 1801 PTHIAPPAAGT-------APGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILS 1853
             T +   A  T        P    G T   + +   A  TA+        ST G   IL+
Sbjct: 4836 STVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILT 4895

Query: 1854 KQVSLPTSMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTA 1913
            +   L T+   +A  G T  TP+++   T ++ EP      T     T+ A S  +    
Sbjct: 4896 E---LTTTATTTASTGST-ATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGT 4951

Query: 1914 PQDSMLVLLPQLAEAHGT---SAGPHLAAEPVDEATTEPSGRS---APALSIVEGLAEAL 1967
            P  S     P +  +  T   S G   A   +    T P+  S    P+ S+        
Sbjct: 4952 PHVSTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLS 5011

Query: 1968 ATTTEANTSTTCVPIAEQDCV 1988
             TTT   T +T  P +  + V
Sbjct: 5012 QTTTPTATMSTATPSSTPETV 5032



 Score = 79.0 bits (193), Expect = 6e-14
 Identities = 71/280 (25%), Positives = 120/280 (42%), Gaps = 44/280 (15%)

Query: 913  CTAYGDRHYRTFDGLPFDFVGACKV-------------HLVKSTSDVSFSVIVENVNCYS 959
            C+ +G  HY+TFDG  F F G C               ++    S  S +  +  V    
Sbjct: 81   CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQESAAPTLSRVLMKV 140

Query: 960  SGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLL 1019
             G++    I +  G+ L+     +G+P    F   +  V   +   +T V   +  + L+
Sbjct: 141  DGVV----IQLTKGSVLV-----NGHPVLLPF--SQSGVLIQQSSSYTKVE-ARLGLVLM 188

Query: 1020 WDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDT 1079
            W+   ++ ++   ++  +  GLCG+F+   +       N +LT P EFG+    ++  D 
Sbjct: 189  WNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLT-PMEFGN----LQKMD- 242

Query: 1080 LDPRDMCVLNPLREPFAKKECS--------ILLSEVFEICHPVVDVTWFYSNCLTDTCGC 1131
             DP + C  +P+ EP   + CS        +L  ++F  C  +VDV  +   C  D C C
Sbjct: 243  -DPTEQCQ-DPVPEP--PRNCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFC 298

Query: 1132 SQGGDCECFCASVSAYAHQCCQ-HGVAVDWRTPRLCPYDC 1170
                   C C +++ Y+ QC    G+  DWR P  CP  C
Sbjct: 299  EDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKC 338



 Score = 75.1 bits (183), Expect = 9e-13
 Identities = 115/455 (25%), Positives = 168/455 (36%), Gaps = 80/455 (17%)

Query: 1398 VPTEALGNE-TLPPSQGLP--TPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTA 1454
            +P+  LG   TLP     P  T S   P  + E+  T T    LT  A  T A +   T 
Sbjct: 3652 IPSFTLGTTGTLPEQTTTPMATMSTIHPSSTPETTHTST---VLTTKATTTRATSSMST- 3707

Query: 1455 TEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQ 1514
               P  +PG T    +     T +    GPT +P+S   T  +L  P T  + ++P    
Sbjct: 3708 ---PSSTPGTTWILTELTTAATTTAA-TGPTATPSSTPGTTWILTEPSTTATVTVPTG-S 3762

Query: 1515 TPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRT--- 1571
            T T         T +V    A +P + +SSR+ P+      T    +R   + P  T   
Sbjct: 3763 TATASSTRATAGTLKVLTSTATTPTV-ISSRATPSSSPGTATALPALRSTATTPTATSVT 3821

Query: 1572 ------------------TPLQPSLTASPSSRP--VASPGAISRSPTSSGSHKAVLTPAV 1611
                              TP     TA+PSS P  V +   ++ + T++ +  +V TP+ 
Sbjct: 3822 AIPSSSLGTAWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSS 3881

Query: 1612 TKVISRTG-VPQPTQ----AQSASSPSTPLT----VAGTAAEQV------PVSPLATRSL 1656
            T   + T  VP  T     A  +SSP T LT    ++ T           P S   T   
Sbjct: 3882 TPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHT 3941

Query: 1657 EIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPRPAQHTTMATRSPALPPETP--AAASL 1714
              VL+T              +S Q       PP P  +TT  T   +LPP +P     + 
Sbjct: 3942 ATVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVP--NTTATTHGRSLPPSSPHTVRTAW 3999

Query: 1715 STATDGLAATPFMS-----------------------LESTRPSQLLSGLPPD--TSLPL 1749
            ++AT G+  T  ++                       L S  PS   +  PP   T+ P 
Sbjct: 4000 TSATSGILGTTHITEPSTVTSHTPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPG 4059

Query: 1750 AKVGTSAPVATPGPKASVITTPLQPQATTLPAQTL 1784
               GTS   AT  P  +  +T L    T+ P  T+
Sbjct: 4060 HTRGTSRTTATATPSKTRTSTLLPSSPTSAPITTV 4094



 Score = 73.9 bits (180), Expect = 2e-12
 Identities = 104/444 (23%), Positives = 158/444 (35%), Gaps = 89/444 (20%)

Query: 2019 GLAVRVGGDRCC---PLWECACR-----CSIFPDLSFVTFDGSHVALFKEAIYILSQSPD 2070
            G  +RV  + C      WEC+ R     C  + D  F+TFDG   +      YIL+Q   
Sbjct: 1526 GETIRVDCNTCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYC 1585

Query: 2071 EMLTVH-VLDCKSANLGHLNWPPFCLVMLNM---THLAHQVTI------DRFNRKVTVDL 2120
               T H      + N+        C   + +      A  V+       +   R+ +V  
Sbjct: 1586 GDNTTHGTFRIVTENIPCGTTGTTCSKAIKLFVEVRTAPAVSTPDPAANEPAPREASVGF 1645

Query: 2121 QPVWPPVSRYGFRIEDTGH-------------------MYMILTPSDIQIQWLHSSGLMI 2161
            +   PP+  Y   +++                      +++++    + + W   + + I
Sbjct: 1646 RQRLPPLQSYELILQEGTFKAVARGPGGDPPYKIRYMGIFLVIETHGMAVSWDRKTSVFI 1705

Query: 2162 VEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQV----PSSLTSV 2217
                +  K +  GLCG  D +A ND   +  SVVG   D   F +SW++    P +L   
Sbjct: 1706 -RLHQDYKGRVCGLCGNFDDNAINDFATRSRSVVG---DALEFGNSWKLSPSCPDALAPK 1761

Query: 2218 GQTRFRP--DSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----- 2270
                  P   S A   CS    ++   TF+AC   V    + E  + D            
Sbjct: 1762 DPCTANPFRKSWAQKQCS----ILHGPTFAACRSQVDSTKYYEACVNDACACDSGGDCEC 1817

Query: 2271 -CVALTVYVAMCHKFHVCIEWRRSDYCPFLC-------SSDSTYQACVTACEPPKTCQDG 2322
             C A+  Y   CH   +C+ WR  D CP  C         +  YQ C   C   KTC++ 
Sbjct: 1818 FCTAVAAYAQACHDAGLCVSWRTPDTCPLFCDFYNPHGGCEWHYQPCGAPC--LKTCRN- 1874

Query: 2323 ILGPLDPEHCQV---LGEGCV--CSEGTILHRRHSALCIPEAKCACTDSMG--------V 2369
                    HC V     EGC   C             C+  A+C C D  G        V
Sbjct: 1875 -----PSGHCLVDLPGLEGCYPKCPPSQPFFNEDQMKCV--AQCGCYDKDGNYYDVGARV 1927

Query: 2370 PRALG-ETWNSSLSGC-CQHQCQA 2391
            P A   ++ N + SG  C H  +A
Sbjct: 1928 PTAENCQSCNCTPSGIQCAHSLEA 1951



 Score = 72.0 bits (175), Expect = 8e-12
 Identities = 135/593 (22%), Positives = 208/593 (35%), Gaps = 75/593 (12%)

Query: 1431 TPTHRPALTPAAPLTTALNPPVTATE-EPVVSPGPTQTTLQQPLELTASQLPAGPTESP- 1488
            T T R A  P    TTA  P VT+++  P  SPG T T L  P   + +  P   + +P 
Sbjct: 2620 TSTLRTAPPPKVLTTTATTPTVTSSKATPSSSPG-TATAL--PALRSTATTPTATSVTPI 2676

Query: 1489 --ASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRV---TVIFAGSPNITVS 1543
              +S G T + L+   TP ++     + T TP        T+ V   T    G+     +
Sbjct: 2677 PSSSLGTTWTRLSQTTTPTAT-----MSTATPSSTPETAHTSTVLTATATTTGATGSVAT 2731

Query: 1544 SRSPPAPRFPLMTKAVTVRGHGSLPVRT--TPLQPSLTASPSSRPVASPGAISRSPTSSG 1601
              S P           T  G  + P  +  T L P +  S ++ P      ++ S     
Sbjct: 2732 PSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGT 2791

Query: 1602 SHKAVLTPAVTKVISRTGVPQPTQAQSAS----SPSTPLTVAGTAAEQVPVSPLATRSLE 1657
            +H A +    T  ++   +  P+ +   S    +P  P T+A T    +P  P +  ++ 
Sbjct: 2792 THTATVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTMATTHGRSLP--PSSPHTVR 2849

Query: 1658 IVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPRPAQHTTMA----------TRSPALPPE 1707
               ++       +  +  P++   H L +A     QH+T A          T SP  P  
Sbjct: 2850 TAWTSATSGILGTTHITEPSTVTSHTL-AATTGTTQHSTPALSSPHPSSRTTESPPSPGT 2908

Query: 1708 TPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAPVATPGPKASV 1767
            T    + +T+     ATP      TR S LL   P           TSAP+ T      V
Sbjct: 2909 TTPGHTTATSRTTATATP----SKTRTSTLLPSSP-----------TSAPITT------V 2947

Query: 1768 ITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAP-GLLLGAT----LP 1822
            +T   +PQ         S  +P         +     A  A    P GL   A     +P
Sbjct: 2948 VTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVP 3007

Query: 1823 TSGVLPVAEGTASMVSVVPRKSTTGKVAI-LSKQVSLPTSMYGSAEGGPT-------ELT 1874
               +  V E +     V   +   GK  +  + ++ +    YG     P          T
Sbjct: 3008 LRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSST 3067

Query: 1875 PATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLAEAHGTSAG 1934
            P T+  LT L       ++  +   P+S         T P  +  V +P  + A  +S  
Sbjct: 3068 PGTTWILTELTTTATTTESTGSTATPSS-TPGTTWILTEPSTTATVTVPTGSTATASSTQ 3126

Query: 1935 PHLAAEPVDEATTEPSGRSAPALSIVE-GLAEAL-----ATTTEANTSTTCVP 1981
                   V    T P+  S+ A      G A AL       TT   TS T +P
Sbjct: 3127 ATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIP 3179



 Score = 69.3 bits (168), Expect = 5e-11
 Identities = 155/655 (23%), Positives = 233/655 (35%), Gaps = 132/655 (20%)

Query: 1407 TLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQ 1466
            T PP+  L T +    Q    +P+ PT  P LT A        PP + T  P +S G T 
Sbjct: 2302 TPPPTTELETATTTTTQALFSTPQ-PTSSPGLTRA--------PPASTTAVPTLSEGLTS 2352

Query: 1467 TTLQQPLELTAS---QLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSG 1523
                  L    +     PAG TE P   GV  S L     P  S+LP           +G
Sbjct: 2353 PRYTSTLGTATTGGPTTPAGSTE-PTVPGVATSTL-----PTRSALPGT---------TG 2397

Query: 1524 AMETTRVTVIFAGSPNITVSSRSPP------APRFPLMTKAVTVRGHGSLPVRTTPLQPS 1577
            ++ T R +     +P    +SR+ P      A + PL T           P  T+ L  S
Sbjct: 2398 SLGTWRPSQPPTLAPTTMATSRARPTGTASTASKEPLTTSLA--------PTLTSELSTS 2449

Query: 1578 LTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPST--P 1635
               + + R   +   ++ + TS G+ +       T+      V  PT   +     T   
Sbjct: 2450 QAETSTPRTETTMSPLTNTTTSQGTTRCQPKCEWTEWFD---VDFPTSGVAGGDMETFEN 2506

Query: 1636 LTVAG-----------TAAEQVP------VSPLATRSLEIVLSTEKGEAGHSQPMGSPAS 1678
            +  AG             AE  P      V  + T SLE  L+ +  +      M    +
Sbjct: 2507 IRAAGGKMCWAPKSIECRAENYPEVSIDQVGQVLTCSLETGLTCKNEDQTGRFNMCFNYN 2566

Query: 1679 PQPHPLPSAPPRPAQHTTMATRSPALPPET------PAAASLSTATDGLAATPFMSLEST 1732
             +          P+   T +T +P+  P T      P   + +TA+ G  ATP  +L + 
Sbjct: 2567 VRVLCCDDYSHCPSTPATSSTATPSSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTA 2626

Query: 1733 RPSQLL-----------------SGLPPDTSLPLAKVGTSAPVA---TPGPKASVITTPL 1772
             P ++L                 S     T+LP  +   + P A   TP P +S+ TT  
Sbjct: 2627 PPPKVLTTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTWT 2686

Query: 1773 QPQATTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVAEG 1832
            +   TT P  T+S   P   +    AH  T +   A  T  G       P+S       G
Sbjct: 2687 RLSQTTTPTATMSTATP--SSTPETAHTSTVLT--ATATTTGATGSVATPSS-----TPG 2737

Query: 1833 TASMVSVVPRKSTTGKVAILSKQ--VSLPTSMYGSAEGGPT--------ELTPATSHPLT 1882
            TA   + VP  +TTG  A  S     +L   ++ S    PT           P T+H  T
Sbjct: 2738 TAH-TTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTAT 2796

Query: 1883 PLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLAEAHGTS---AGPHLAA 1939
             L         G ++  P+S   +  +  T P  +       +A  HG S   + PH   
Sbjct: 2797 VLTTTTTTVATG-SMATPSSSTQTSGTTHTPPVPN------TMATTHGRSLPPSSPHTVR 2849

Query: 1940 EPVDEAT---------TEPSGRSAPALSIVEGLAE----ALATTTEANTSTTCVP 1981
                 AT         TEPS  ++  L+   G  +    AL++   ++ +T   P
Sbjct: 2850 TAWTSATSGILGTTHITEPSTVTSHTLAATTGTTQHSTPALSSPHPSSRTTESPP 2904



 Score = 69.3 bits (168), Expect = 5e-11
 Identities = 105/439 (23%), Positives = 159/439 (36%), Gaps = 58/439 (13%)

Query: 1429 PRTPTHRPALTPAA-PLTTALNPPVTATEEPVVSPGPTQTT---------LQQPLELTAS 1478
            P TP      TP++ P TT +   +T T     S G T T          L +P      
Sbjct: 4200 PSTPATSSTATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEPSTTATV 4259

Query: 1479 QLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSP 1538
             +P G T + +S   TA     PH   +++ P    +      S    T          P
Sbjct: 4260 TVPTGSTATASSTQATA---GTPHVSTTATTPTVTSSKATPFSSPGTAT--------ALP 4308

Query: 1539 NITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRTTPLQPSLTASPSSRP--VASPGAISRS 1596
             +  ++ +P A  F  +  +        L   TTP     TA+PSS P    +   ++ +
Sbjct: 4309 ALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTT 4368

Query: 1597 PTSSGSHKAVLTPAVTK-VISRTGVPQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRS 1655
             T++ +  +V TP+ T      T VP  T      +PS+              SP   R+
Sbjct: 4369 ATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSS--------------SPGTART 4414

Query: 1656 LEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPRPAQHTTMATRSPALPPETPAAASLS 1715
              + +ST       + P  S ++  P  +P     P   T + T +  +   + A  S S
Sbjct: 4415 PPVWISTT------TTPTTSGSTVTPSSVPGTTHTP---TVLTTTTTTVATGSMATPSSS 4465

Query: 1716 TATDGLAAT-PFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTPLQP 1774
            T T G   T P  +  +T   + LS   P T        TS  + T         T   P
Sbjct: 4466 TQTSGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTP 4525

Query: 1775 QATTLPAQTLSPVL--PFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLP----TSGVLP 1828
             ATT   Q  +P L  P   +  T++ P      P   TA         P    TS +LP
Sbjct: 4526 AATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLP 4585

Query: 1829 VAEGTASMVSVVPRKSTTG 1847
             +  +A + +VV    TTG
Sbjct: 4586 SSPTSAPITTVV----TTG 4600



 Score = 68.9 bits (167), Expect = 7e-11
 Identities = 79/314 (25%), Positives = 115/314 (36%), Gaps = 52/314 (16%)

Query: 895  CVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDV--SFSVIV 952
            CV  RG     + P A  C+ +G  HY TFDG  + F G C   L++       + S+ +
Sbjct: 5397 CVGGRG-----ITPGAGICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYL 5451

Query: 953  ENVNCYSSGMI------CRKFISINVGN---------------SLIVFDDDSGNPSPESF 991
            +N  C +S         C + +SI+  +                LI+FD       P S 
Sbjct: 5452 DNHYCTASATAAAAAARCPRALSIHYKSMDIVLTVTMVHGKEEGLILFDQ-----IPVSS 5506

Query: 992  LDDKQEVHTWRVGFFTL-VHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNF----- 1045
               K  V    +G  T+ V  P   +++ ++ +          +     G CG       
Sbjct: 5507 GFSKNGVLVSVLGTTTMRVDIPALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQR 5566

Query: 1046 ------DLKTINEMRTPENLELTNPQEFGSSWAAVECPDTLDPRDMCVLNPLREPFAKKE 1099
                  D  T    +      L         WA    P T  P       P   P   + 
Sbjct: 5567 DDCLQRDGTTAASCKDMAKTWLVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQP 5626

Query: 1100 -CSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV 1158
             C ++LS+VF  CH +V    F++ C++D C     G  E  C S+ AYA  C   GV  
Sbjct: 5627 LCDLMLSQVFAECHNLVPPGPFFNACISDHC----RGRLEVPCQSLEAYAELCRARGVCS 5682

Query: 1159 DWR--TPRLCPYDC 1170
            DWR  T  LC   C
Sbjct: 5683 DWRGATGGLCDLTC 5696



 Score = 67.8 bits (164), Expect = 1e-10
 Identities = 84/375 (22%), Positives = 135/375 (36%), Gaps = 36/375 (9%)

Query: 2039 CSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVML 2098
            CS + D  + TFDG          Y+ S+          +  +   +G         V+ 
Sbjct: 733  CSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCRAAYEDFNVQLRRGLVGSRP------VVT 786

Query: 2099 NMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSG 2158
             +   A  + ++  N  V ++ Q    P SR G  +E +G    +     +   W +   
Sbjct: 787  RVVIKAQGLVLEASNGSVLINGQREELPYSRTGLLVEQSGDYIKVSIRLVLTFLW-NGED 845

Query: 2159 LMIVEASKTSKAQGHGLCGICDG-DAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSV 2217
              ++E       Q  GLCG  +G  A N+    +  +      P  F +  ++       
Sbjct: 846  SALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLT-----PLQFGNLQKLDGPTEQC 900

Query: 2218 GQTRFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDT-KYVQQPCVALTV 2276
                  P    T +   C R +    F+ CH  V   ++     +D  +    PC     
Sbjct: 901  PDPLPLPAGNCTDEEGICHRTLLGPAFAECHALVDSTAYLAACAQDLCRCPTCPCATFVE 960

Query: 2277 YVAMC-HKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVL 2335
            Y   C H       WR  + CP  C  +  +Q C + C    TC +     L  +HC   
Sbjct: 961  YSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPC--TDTCSNPQRAQLCEDHCV-- 1016

Query: 2336 GEGCVCSEG---TILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGC-CQ---HQ 2388
             +GC C  G   T+L     + C+P  +C CT   G   + G ++N++ S C C     Q
Sbjct: 1017 -DGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHG-GRTYSPGTSFNTTCSSCTCSGGLWQ 1074

Query: 2389 CQAPDTIVPVDLGCP 2403
            CQ        DL CP
Sbjct: 1075 CQ--------DLPCP 1081



 Score = 67.8 bits (164), Expect = 1e-10
 Identities = 120/437 (27%), Positives = 155/437 (35%), Gaps = 97/437 (22%)

Query: 1501 PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSS-RSPPAPRFPLMTKAV 1559
            P TP +SS      TP    +     TT  T    GS     S+ R+ P P+  L T A 
Sbjct: 2579 PSTPATSSTATPSSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPKV-LTTTA- 2636

Query: 1560 TVRGHGSLPVRTTPLQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTG 1619
                       TTP   S  A+PSS    SPG             A   PA+     R+ 
Sbjct: 2637 -----------TTPTVTSSKATPSS----SPGT------------ATALPAL-----RST 2664

Query: 1620 VPQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASP 1679
               PT       PS+ L    T   Q   +P AT S     ST   E  H+  + +  + 
Sbjct: 2665 ATTPTATSVTPIPSSSLGTTWTRLSQT-TTPTATMSTATPSSTP--ETAHTSTVLTATAT 2721

Query: 1680 QPHPLPSAPPRPAQHTTMATRSPALPPETPAAASL----STATDGLAATPFMSLESTRPS 1735
                           TT AT S A P  TP  A      +T T G  ATP     S+ P 
Sbjct: 2722 ---------------TTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATP-----SSSPG 2761

Query: 1736 QLLSGLPP----DTSLPLAKVGTSAPVATPGP--KASVITTPLQPQATTLPAQTLSPVLP 1789
              L+  PP     T+ P  +  T  P + PG    A+V+TT     AT   A        
Sbjct: 2762 TALT--PPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMA-------- 2811

Query: 1790 FTPAAMTQAHPPTHI--APPAAGTAPGLLLGATLP----------TSGVLPVAEGT-ASM 1836
             TP++ TQ    TH    P    T  G  L  + P          TSG+L     T  S 
Sbjct: 2812 -TPSSSTQTSGTTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPST 2870

Query: 1837 VSVVPRKSTTGKVAILSKQVSLPTSMYGSAEGGPTELTPATSHPL----TPLVAEPEGAQ 1892
            V+     +TTG     +  +S P     + E  P+  T    H      T   A P   +
Sbjct: 2871 VTSHTLAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTR 2930

Query: 1893 AGTALP-VPTSYALSRV 1908
              T LP  PTS  ++ V
Sbjct: 2931 TSTLLPSSPTSAPITTV 2947



 Score = 67.8 bits (164), Expect = 1e-10
 Identities = 112/512 (21%), Positives = 170/512 (33%), Gaps = 56/512 (10%)

Query: 1501 PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGS-------------PNITVSSRSP 1547
            P TP +SS      TP    +     T   T    GS             P +  S+ + 
Sbjct: 3555 PSTPATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATT 3614

Query: 1548 PAPRFPLMTKAVTVRGHGSLPVRTTPLQPSLTASPSSRPVASPGAISRSPTSSGSHKAVL 1607
            P       T + + R   +LPV T+    S   S +  P  + G     P  + +  A +
Sbjct: 3615 PTATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLPEQTTTPMATM 3674

Query: 1608 TPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEA 1667
            +      I  +  P+ T   +  +     T A T++   P S   T  +   L+T     
Sbjct: 3675 S-----TIHPSSTPETTHTSTVLTTKATTTRA-TSSMSTPSSTPGTTWILTELTTAATTT 3728

Query: 1668 GHSQPMGSPASPQPHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFM 1727
              + P  +P+S          P      T+ T S A    T A A         A TP +
Sbjct: 3729 AATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTATTPTV 3788

Query: 1728 SLESTRPSQLLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPV 1787
                  PS   S     T+LP  +   + P AT     + I +     A T  +QT +P 
Sbjct: 3789 ISSRATPS---SSPGTATALPALRSTATTPTAT---SVTAIPSSSLGTAWTRLSQTTTPT 3842

Query: 1788 LPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTG 1847
               + A  +      H +     T        ++ T    P   GTA   + VP  +TTG
Sbjct: 3843 ATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTP---GTAH-TTKVPTTTTTG 3898

Query: 1848 KVAILSKQVSLPTSMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSR 1907
              A        P+S  G+A   P  ++  T+         P      +++P  T  A   
Sbjct: 3899 FTA-------TPSSSPGTALTPPVWISTTTTPTTRGSTVTP------SSIPGTTHTATVL 3945

Query: 1908 VSARTAPQDSMLVLLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALS-------IV 1960
             +  T      +       +  GT+  P     PV   T    GRS P  S         
Sbjct: 3946 TTTTTTVATGSMATPSSSTQTSGTTHTP-----PVPNTTATTHGRSLPPSSPHTVRTAWT 4000

Query: 1961 EGLAEALATT--TEANTSTTCVPIAEQDCVRH 1990
               +  L TT  TE +T T+  P A     +H
Sbjct: 4001 SATSGILGTTHITEPSTVTSHTPAATTSTTQH 4032



 Score = 66.2 bits (160), Expect = 4e-10
 Identities = 151/628 (24%), Positives = 222/628 (35%), Gaps = 118/628 (18%)

Query: 1397 WVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATE 1456
            W+ TE     T+     +PT S      +Q +  TP            TTA  P VT+++
Sbjct: 3101 WILTEPSTTATVT----VPTGSTATASSTQATAGTPHVS---------TTATTPTVTSSK 3147

Query: 1457 -EPVVSPGPTQTTLQQPLELTASQLPAGPTESPASK-GVTASLLAIPHTPESSSLPVALQ 1514
              P  SPG T T L        +      T  P+S  G T + L+   TP ++     + 
Sbjct: 3148 ATPFSSPG-TATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTAT-----MS 3201

Query: 1515 TPTPGMVSGAMETTRV---TVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLP--- 1568
            T TP      + T+ V   T    G+     +  S P           T  G  + P   
Sbjct: 3202 TATPSSTPETVHTSTVLTTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSS 3261

Query: 1569 ---VRTTPLQPSLTASPSSR-----PVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV 1620
                RT P+  S T +P++R     P + PG  + +PT       VLT   T V + +  
Sbjct: 3262 PGTARTLPVWISTTTTPTTRGSTVTPSSIPGT-THTPT-------VLTTTTTTVATGSMA 3313

Query: 1621 PQPTQAQSAS---SPSTPLTVAGTAAEQV-PVSPLATRSLEIVLSTEKGEAGHSQPMGSP 1676
               +  Q++    +P  P T A T    + P SP   R+     S   G  G +  +  P
Sbjct: 3314 TPSSSTQTSGTTHTPPVPNTTATTHGRSLSPSSPHTVRT--AWTSATSGTLGTTH-ITEP 3370

Query: 1677 ASPQPHPLPSAPPRPAQHTTMA----------TRSPALPPETPAAASLSTATDGLAATPF 1726
            ++   H  P+A     QH+T A          T SP  P  T    + +T+     ATP 
Sbjct: 3371 STGTSH-TPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRATSRTTATATP- 3428

Query: 1727 MSLESTRPSQLLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSP 1786
                 TR S LL   P           TSAP+ T      V+T   +PQ         S 
Sbjct: 3429 ---SKTRTSTLLPSSP-----------TSAPITT------VVTMGCEPQCAWSEWLDYSY 3468

Query: 1787 VLPFTPAAMTQAHPPTHIAPPAAGTAP-GLLLGAT----LPTSGVLPVAEGTASMVSVVP 1841
             +P         +     A  A    P GL   A     +P   +  V E +     V  
Sbjct: 3469 PMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCR 3528

Query: 1842 RKSTTGKVAI-LSKQVSLPTSMYGSAEGGPTELTPATSHPLTPLVAE------PEGAQAG 1894
             +   GK  +  + ++ +    YG         TPATS   TP           E   A 
Sbjct: 3529 NREQVGKFKMCFNYEIRVFCCNYGHCPS-----TPATSSTATPSSTPGTTWILTEQTTAA 3583

Query: 1895 TALPVPTSYALSRVSARTAPQDSMLVLLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSA 1954
            T      S A+   +  TAP   +L           T+  P   +    +AT+  S R+A
Sbjct: 3584 TTTATTGSTAIPSSTPGTAPPPKVLT---------STATTPTATS---SKATSSSSPRTA 3631

Query: 1955 PALSIVEGLAEALATTTEANTSTTCVPI 1982
              L +       L +T   +T+T+  PI
Sbjct: 3632 TTLPV-------LTSTATKSTATSFTPI 3652



 Score = 66.2 bits (160), Expect = 4e-10
 Identities = 140/612 (22%), Positives = 207/612 (33%), Gaps = 86/612 (14%)

Query: 1397 WVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATE 1456
            W+ TE     T+     +PT S      +Q +  TP            TTA  P VT+++
Sbjct: 4248 WILTEPSTTATVT----VPTGSTATASSTQATAGTPHVS---------TTATTPTVTSSK 4294

Query: 1457 -EPVVSPGPTQTTLQQPLELTASQLPAGPTESPASK-GVTASLLAIPHTPESS-SLPVAL 1513
              P  SPG T T L        +      T  P+S  G T + L+   TP ++ S     
Sbjct: 4295 ATPFSSPG-TATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPS 4353

Query: 1514 QTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRT-- 1571
             TP     S  + TT  T    GS     +  S P           T  G    P  +  
Sbjct: 4354 STPETAHTSTVLTTTATTTRATGS---VATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPG 4410

Query: 1572 TPLQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSAS- 1630
            T   P +  S ++ P  S   ++ S     +H   +    T  ++   +  P+ +   S 
Sbjct: 4411 TARTPPVWISTTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSG 4470

Query: 1631 ---SPSTPLTVAGTAAEQV-PVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPS 1686
               +P  P T A T    + P SP   R+     S   G  G +  +  P++   H  P+
Sbjct: 4471 TTHTPPVPNTTATTHGRSLSPSSPHTVRT--AWTSATSGTLGTTH-ITEPSTGTSH-TPA 4526

Query: 1687 APPRPAQHTTMA----------TRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQ 1736
            A     QH+T A          T SP  P  T    + +T+     ATP      TR S 
Sbjct: 4527 ATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATP----SKTRTST 4582

Query: 1737 LLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMT 1796
            LL   P           TSAP+ T      V+TT  +PQ         S  +P       
Sbjct: 4583 LLPSSP-----------TSAPITT------VVTTGCEPQCAWSEWLDYSYPMPGPSGGDF 4625

Query: 1797 QAHPPTHIAPPAAGTAP-GLLLGAT----LPTSGVLPVAEGTASMVSVVPRKSTTGKVAI 1851
              +     A  A    P GL   A     +P   +  V E +     V   +   GK  +
Sbjct: 4626 DTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLGELGQVVECSLDFGLVCRNREQVGKFKM 4685

Query: 1852 -LSKQVSLPTSMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSA 1910
              + ++ +    YG         TPATS    P  + P      T L    +   S  S 
Sbjct: 4686 CFNYEIRVFCCNYGHCPS-----TPATSSTAMP-SSTPGTTWILTELTTTATTTASTGST 4739

Query: 1911 RTAPQDSMLVLLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATT 1970
             T             +   GT+  P +   P    T   S  ++ +          L +T
Sbjct: 4740 ATP------------SSTPGTAPPPKVLTSPATTPTATSSKATSSSSPRTATTLPVLTST 4787

Query: 1971 TEANTSTTCVPI 1982
               +T+T+  PI
Sbjct: 4788 ATKSTATSVTPI 4799



 Score = 64.3 bits (155), Expect = 2e-09
 Identities = 76/301 (25%), Positives = 117/301 (38%), Gaps = 20/301 (6%)

Query: 1428 SPRTPTHRPALTPAAPL--TTALNPPVTA-TEEPVVSPGPTQTTLQQPLELTASQLPAGP 1484
            S  TP+  P    A P   +TA  P  T+ T  P  S G T T L Q    TA+   A P
Sbjct: 4966 SKATPSSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATP 5025

Query: 1485 TESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSS 1544
            + +P +   T+++L    T   ++  VA  + TPG        T  T  F  +P+ +  +
Sbjct: 5026 SSTPETVH-TSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGT 5084

Query: 1545 RSPPAPRFPLMTKAVTVRGHGSLPVRTTPLQPSLTASPSSRPVASPGAISRSPTSSGSHK 1604
               P    P+ T +     H S    TT     LT + +     +  A   +P+S+    
Sbjct: 5085 ALTPPTTTPMSTMSTI---HTSSTPETTHTSTVLTTTATMTRATNSTA---TPSSTLGTT 5138

Query: 1605 AVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTAAE-QVPVSPLATRSLEIVLSTE 1663
             +LT   T   +           S    +  LT   T A   VP    AT S  +     
Sbjct: 5139 RILTELTTTATTTAATGSTATLSSTPGTTWILTEPSTIATVMVPTGSTATASSTL----- 5193

Query: 1664 KGEAGHSQPMGSPASPQPHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAA 1723
             G A   + + + A+    P  +A   P+  T   TR+PA+ P +    S+ST +  +  
Sbjct: 5194 -GTAHTPKVVTTMATM---PTATASTVPSSSTVGTTRTPAVLPSSLPTFSVSTVSSSVLT 5249

Query: 1724 T 1724
            T
Sbjct: 5250 T 5250



 Score = 61.2 bits (147), Expect = 1e-08
 Identities = 63/260 (24%), Positives = 104/260 (40%), Gaps = 22/260 (8%)

Query: 2160 MIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQ 2219
            + V      + Q  GLCG  + + A+D T   G V       A F ++W+  ++  +   
Sbjct: 1205 VFVRLDPAHQGQMCGLCGNFNQNQADDFTALSGVVEATG---AAFANTWKAQAACANARN 1261

Query: 2220 TRFRPDSCATTDCSP----CLRMVS-NRTFSACHRFVPPESFCELWIRDTKYVQQP---- 2270
            +   P S +  + +     C R+   N  FS CH  + P+ F    + DT   ++     
Sbjct: 1262 SFEDPCSLSVENENYARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNCERSEDCL 1321

Query: 2271 CVALTVYVAMCHKFHVCI-EWRRSDYCPFL--CSSDSTYQACVTACEPPKTCQDGILGPL 2327
            C AL+ YV  C    V + +WR      ++  C     Y   V AC+P  TC+      +
Sbjct: 1322 CAALSSYVHACAAKGVQLSDWRDGVCTKYMQNCPKSQRYAYVVDACQP--TCRGLSEADV 1379

Query: 2328 DPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWN--SSLSGCC 2385
                  V  +GC C  GT L+   +  C+P  +C C  + G   A GE  +   ++  C 
Sbjct: 1380 TCSVSFVPVDGCTCPAGTFLN--DAGACVPAQECPCY-AHGTVLAPGEVVHDEGAVCSCT 1436

Query: 2386 QHQCQAPDTIVPVDLGCPSP 2405
              +       +    GC +P
Sbjct: 1437 GGKLSCLGASLQKSTGCAAP 1456



 Score = 60.1 bits (144), Expect = 3e-08
 Identities = 123/591 (20%), Positives = 193/591 (32%), Gaps = 81/591 (13%)

Query: 1428 SPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTES 1487
            S  TP+  P       + T      TAT  P  SPG   T L  P+ ++        T +
Sbjct: 3875 SVATPSSTPGTAHTTKVPTTTTTGFTAT--PSSSPG---TALTPPVWIST-------TTT 3922

Query: 1488 PASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSP 1547
            P ++G T +  +IP T  ++++   L T T  + +G+M T       + S   + ++ +P
Sbjct: 3923 PTTRGSTVTPSSIPGTTHTATV---LTTTTTTVATGSMATP------SSSTQTSGTTHTP 3973

Query: 1548 PAPRFPLMTKAVTVRGHGSLPVRTTPLQPSLTASPS----SRPVASPGAI-SRSPTSSGS 1602
            P P         T  G    P     ++ + T++ S    +  +  P  + S +P ++ S
Sbjct: 3974 PVPN-----TTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTPAATTS 4028

Query: 1603 HKAVLTPAVTKVISRTGVPQPTQAQSASSPS----TPLTVAGTAAEQVPVSPLATRSLEI 1658
                 TPA++        P P+   + S PS    TP    GT+      +P  TR+   
Sbjct: 4029 TTQHSTPALSS-------PHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPSKTRT-ST 4080

Query: 1659 VLSTEKGEAGHSQPMGSPASPQ---------PHPLPSAPPRPAQHTTMATRSPALPPETP 1709
            +L +    A  +  + +   PQ          +P+P   P      T +    A      
Sbjct: 4081 LLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPG--PSGGDFDTYSNIRAAGGAVCE 4138

Query: 1710 AAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAPV----------- 1758
                L          P   L       L  GL       + K                  
Sbjct: 4139 QPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGH 4198

Query: 1759 ATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLG 1818
                P  S   TP     TT     L+     T +  + A P +        T P     
Sbjct: 4199 CPSTPATSSTATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEPSTTAT 4258

Query: 1819 ATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGSAEGGPTELTPATS 1878
             T+PT      +   A+  +  P  STT     ++   + P S  G+A   P   + AT+
Sbjct: 4259 VTVPTGSTATASSTQAT--AGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATT 4316

Query: 1879 HPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLAEAHGTSAGPHLA 1938
               T   A P  +   T          +R+S  T P  +M    P       T    H +
Sbjct: 4317 PTATSFTAIPSSSLGTT---------WTRLSQTTTPTATMSTATPS-----STPETAHTS 4362

Query: 1939 AEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVPIAEQDCVR 1989
                  ATT  +  S    S   G A      T   T  T  P +     R
Sbjct: 4363 TVLTTTATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTAR 4413



 Score = 59.3 bits (142), Expect = 5e-08
 Identities = 82/355 (23%), Positives = 119/355 (33%), Gaps = 53/355 (14%)

Query: 1336 CEWRYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCPTPQ-VLDEVTQRCVYLEDCVEP 1394
            CEW Y  C +PC +TCR+P      D+P +EGC P CP  Q   +E   +CV    C + 
Sbjct: 1857 CEWHYQPCGAPCLKTCRNPSGHCLVDLPGLEGCYPKCPPSQPFFNEDQMKCVAQCGCYDK 1916

Query: 1395 -------AVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTP-----AA 1442
                      VPT            G+      E        RT +++  +        A
Sbjct: 1917 DGNYYDVGARVPTAENCQSCNCTPSGIQCAHSLEACTCTYEDRTYSYQDVIYNTTDGLGA 1976

Query: 1443 PLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPH 1502
             L        T   + V  PG   TT   P   T + +P     S  S  +  S + +  
Sbjct: 1977 CLIAICGSNGTIIRKAVACPGTPATT---PFTFTTAWVP----HSTTSPALPVSTVCVRE 2029

Query: 1503 TPESSSLPVALQTPTPGMVSGAMET--------TRVTVIFAGSPNITVSSRSPPAPRFPL 1554
                SS       P PG+  G  ET         +V  + A      +  R+   P  PL
Sbjct: 2030 VCRWSSWYNG-HRPEPGLGGGDFETFENLRQRGYQVCPVLA-----DIECRAAQLPDMPL 2083

Query: 1555 --MTKAVTVRGHGSLPVRTTPLQPSLTASPSSR----------PVASPGAISRSPTSSGS 1602
              + + V       L    +   P L      R          P  +PG   +   S+ +
Sbjct: 2084 EELGQQVDCDRMRGLMCANSQQSPPLCHDYELRVLCCEYVPCGPSPAPGTSPQPSLSAST 2143

Query: 1603 HKAVLTPAVTKVISRTGVPQPTQAQSAS-------SPSTPLTVAGTAAEQVPVSP 1650
              AV TP  T    +T +      +S +       S S P+TV  +A       P
Sbjct: 2144 EPAVPTPTQTTATEKTTLWVTPSIRSTAALTSQTGSSSGPVTVTPSAPGTTTCQP 2198



 Score = 52.4 bits (124), Expect = 6e-06
 Identities = 98/478 (20%), Positives = 161/478 (33%), Gaps = 76/478 (15%)

Query: 1562 RGHGSLPVRTTPLQPSLTASPSS-----RPVASPGAISRSPTSSGSHKAVLTPAVTKVIS 1616
            RG  + P  TT L+ + T +  +     +P +SPG ++R+P +S +    L+  +T    
Sbjct: 2297 RGRATTPPPTTELETATTTTTQALFSTPQPTSSPG-LTRAPPASTTAVPTLSEGLTS--- 2352

Query: 1617 RTGVPQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSP 1676
                P+ T     ++   P T AG+    VP    +T      L    G  G  +P   P
Sbjct: 2353 ----PRYTSTLGTATTGGPTTPAGSTEPTVPGVATSTLPTRSALPGTTGSLGTWRP-SQP 2407

Query: 1677 ASPQPHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATP-----FMSLES 1731
             +  P  + ++  RP    + A++ P      P   S  + +    +TP        L +
Sbjct: 2408 PTLAPTTMATSRARPTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPRTETTMSPLTN 2467

Query: 1732 TRPSQLLSGLPP--------DTSLPLAKVG-----TSAPVATPGPKASVITTPLQPQATT 1778
            T  SQ  +   P        D   P + V      T   +   G K       ++ +A  
Sbjct: 2468 TTTSQGTTRCQPKCEWTEWFDVDFPTSGVAGGDMETFENIRAAGGKMCWAPKSIECRAEN 2527

Query: 1779 LPAQTLSPVLPFTPAAM-----------------------------TQAHPPTHIAPPAA 1809
             P  ++  V      ++                               +H P+  A  + 
Sbjct: 2528 YPEVSIDQVGQVLTCSLETGLTCKNEDQTGRFNMCFNYNVRVLCCDDYSHCPSTPATSST 2587

Query: 1810 GT---APGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGSA 1866
             T    PG     T PT+     A  T S  +      T     +L+   + PT    S+
Sbjct: 2588 ATPSSTPGTTWILTKPTTTATTTA-STGSTATPTSTLRTAPPPKVLTTTATTPT--VTSS 2644

Query: 1867 EGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTS---YALSRVSARTAPQDSMLVLLP 1923
            +  P+  +P T+  L  L +      A +  P+P+S      +R+S  T P  +M    P
Sbjct: 2645 KATPSS-SPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATP 2703

Query: 1924 QLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 1981
                   T    H +      ATT  +  S    S   G A      T   T  T  P
Sbjct: 2704 S-----STPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATP 2756



 Score = 35.4 bits (80), Expect = 0.81
 Identities = 20/57 (35%), Positives = 30/57 (52%), Gaps = 6/57 (10%)

Query: 1339 RYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCPTPQ---VLDEVTQR-CVYLEDC 1391
            ++  C SPC  TC +P+ A   +   V+GC   CP  +   VLD++T   C+ L  C
Sbjct: 990  QHQECGSPCTDTCSNPQRAQLCEDHCVDGC--FCPPGRSCTVLDDITHSGCLPLGQC 1044



 Score = 34.7 bits (78), Expect = 1.4
 Identities = 19/54 (35%), Positives = 26/54 (48%), Gaps = 3/54 (5%)

Query: 1339 RYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCPTPQVLDEVTQR-CVYLEDC 1391
            +Y  C SPC  TC +   +   +   V GC   CP   VLD++ Q  CV +  C
Sbjct: 343  QYHECRSPCADTCSNQEHSRACEDHCVAGC--FCPEGTVLDDIGQTGCVPVSKC 394



 Score = 34.3 bits (77), Expect = 1.8
 Identities = 50/245 (20%), Positives = 93/245 (37%), Gaps = 25/245 (10%)

Query: 1977 TTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECA 2036
            T CVP+++  CV            N + + P       C     +   GG   C    C 
Sbjct: 386  TGCVPVSKCACV-----------YNGAAYAPGATYSTDCTNCTCS---GGRWSCQEVPCP 431

Query: 2037 CRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLV 2096
              CS+     F TFDG    +  +  Y+L++  D      + + +   L        CL 
Sbjct: 432  GTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCGLTD---SETCLK 488

Query: 2097 MLNMT-HLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPS---DIQIQ 2152
             + ++   A  V + + + +V ++      P+S     I      ++I   S    + +Q
Sbjct: 489  SVTLSLDGAQTVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQ 548

Query: 2153 WLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPS 2212
             + +  L +  A K  + Q  GLCG  +   A+D     G V   A   A F ++++  +
Sbjct: 549  LVPTMQLFMQLAPKL-RGQTCGLCGNFNSIQADDFRTLSGVVEATA---AAFFNTFKTQA 604

Query: 2213 SLTSV 2217
            +  ++
Sbjct: 605  ACPNI 609


>gi|134031945 SCO-spondin [Homo sapiens]
          Length = 5147

 Score =  546 bits (1408), Expect = e-155
 Identities = 350/1132 (30%), Positives = 520/1132 (45%), Gaps = 89/1132 (7%)

Query: 79   CRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVS 138
            C +W   H  TFDG +Y+  G+ +Y L G  +    ++++ +    +C   P  C R   
Sbjct: 195  CASWSGFHYRTFDGRHYHFLGRCTYLLAGAAD---STWAVHLTPGDRC-PQPGHCQRVT- 249

Query: 139  LFFVGEQEIHL-AKEVTHGGMRVQLPH--VMGSARLQQLAGYVIVRHQSAFTLAWDGASA 195
               +G +E+ + A  V+  G  V      ++    LQ L  ++++       +  D   +
Sbjct: 250  ---MGPEEVLIQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDRTGS 306

Query: 196  VYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTS 255
            + I +  EL G T GLCG  N  P+DD +   G L      F +SW+   P    G   +
Sbjct: 307  ISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWR--LPGSESGCLDA 364

Query: 256  SLPRPPC-------LQQNPGTMQG-VYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQ 307
                  C           PG ++    + C  LL  PF  CHA VSP  +  +C    C 
Sbjct: 365  VEVAQGCDPLGLIDADVEPGHLRAEAQDVCHQLLEGPFGQCHAQVSPAEYHEACLFAYCA 424

Query: 308  SM-------GDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 360
                     G     C   A Y +ACA+    ++ WR     C   C      Y++C++ 
Sbjct: 425  GAMAGSGQEGRQQAVCATFASYVQACARRHIHIR-WRKP-GFCERLCPGGQL-YSDCVSL 481

Query: 361  CPASCHP-----RASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSV 415
            CP SC         SC +    CV GC CP GL +    CV  A CPC +    Y PG  
Sbjct: 482  CPPSCEAVGQGEEESCREE---CVSGCECPRGLFWNGTLCVPAAHCPCYYCRQRYVPGDT 538

Query: 416  VKEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTF--PATCQYILAKSRSS 473
            V++ CN C C  G+W C+ A+CPAEC+V GD H+ TFDGR Y+F     C+Y L +    
Sbjct: 539  VRQLCNPCVCRDGRWHCAQALCPAECAVGGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVK 598

Query: 474  GTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDA 533
            G   + L++  C     G+C+ ++SV L       + L  +G VL+  Q   +P    + 
Sbjct: 599  GQLLILLEHGAC---DAGSCLHAISVSLED---THIQLRDSGAVLVNGQDVGLPWIGAEG 652

Query: 534  FEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSP 593
              +RR SS FL +R   G +VL+       Y+ +D R      GLCGTF  N QDDFL+P
Sbjct: 653  LSVRRASSAFLLLRW-PGAQVLWGLSDPVAYITLDPRHAHQVQGLCGTFTQNQQDDFLTP 711

Query: 594  VGVPESTPQLFGNSWKTL-SACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCS 652
             G  E++   F + ++       P    + L PC  H Q  +++  AC++L   +F  C 
Sbjct: 712  AGDVETSIAAFASKFQVAGKGRCPSEDSALLSPCTTHSQRHAFAEAACAILHSSVFQECH 771

Query: 653  AFLSPVPYFEQCRRDACRC--GQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEAS 710
              +   P++ +C    C C  G  CLC  L+ YA  C + G    +R +   C + C   
Sbjct: 772  RLVDKEPFYLRCLAAVCGCDPGSDCLCPVLSAYARRCAQEGASPPWRNQ-TLCPVMCPGG 830

Query: 711  KEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQ 770
            +EY  C   CG+ C     PE CG  G        CV GC CP     D +   CVP + 
Sbjct: 831  QEYRECAPACGQHC---GKPEDCGELG-------SCVAGCNCPLGLLWDPEGQ-CVPPSL 879

Query: 771  CSCHFQGVDYPPGDSDIPSLGHCHCKD-GVMSCDSR-APAAA-CPAGQVFVNCSDLHTDL 827
            C C      Y PG + +     C C++ G+ +C +R  P+ A CP   V+   + L    
Sbjct: 880  CPCQLGARRYAPGSATMKECNRCICQERGLWNCTARHCPSQAFCPRELVYAPGACL---- 935

Query: 828  ELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQ 887
                  TC+    N S  A      GC CP G +   + C  P+ CPC   G+ Y P   
Sbjct: 936  -----LTCDSPSANHSCPAGS--TDGCVCPPGTVLLDERCVPPDLCPCRHSGQWYLPNAT 988

Query: 888  VMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVS 947
            +   C+ CVC+   + CT    +  C A G  HY TFDGL F + GAC+  LV+  S + 
Sbjct: 989  IQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREASGL- 1047

Query: 948  FSVIVENVNCYSSGMICRKFISINVGNSLI-------VFDDDSGNPSPESFLDDKQEVHT 1000
            F+V  +N+ C +SG+ C K +++ +  +++       V  +      P+ +      +  
Sbjct: 1048 FTVSAQNLPCGASGLTCTKALAVRLEGTVVHMLRGRAVTVNGVSVTPPKVYTGPGLSLR- 1106

Query: 1001 WRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLE 1060
             R G F L+      +TLLWD  T V VQ  PQ++G++AGLCG+FD    N++R+ + + 
Sbjct: 1107 -RAGLFLLLS-THLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVL 1164

Query: 1061 LTNPQEFGSSW-AAVECPDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTW 1119
                +    SW  +  CP+  D    C +N  R  +A+  C  LL  +F +CH  V    
Sbjct: 1165 EPTAELAAHSWRLSPLCPEPGDLPHPCTMNTHRAGWARARCGALLQPLFTLCHAEVPPQQ 1224

Query: 1120 FYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCD 1171
             Y  CL D CGC  GGDCEC C++++ YA +C +HG  V WR+  LC   C+
Sbjct: 1225 HYEWCLYDACGCDSGGDCECLCSAIATYADECARHGHHVRWRSQELCSLQCE 1276



 Score =  255 bits (651), Expect = 5e-67
 Identities = 153/473 (32%), Positives = 223/473 (47%), Gaps = 29/473 (6%)

Query: 340  LRQCTV-HCKEKAFTYNECI---ACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGC 395
            L  CT  HC  +AF   E +     C  +C   ++         DGC CP G +  D  C
Sbjct: 909  LWNCTARHCPSQAFCPRELVYAPGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLLDERC 968

Query: 396  VAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGR 455
            V P  CPC   G  Y P + ++EDCN C C   +W C+       C  +G  H+ TFDG 
Sbjct: 969  VPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGL 1028

Query: 456  RYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAG 515
             +T+P  C+Y+L +  +SG FTV+ QN PCG +    C ++++V L       V     G
Sbjct: 1029 AFTYPGACEYLLVRE-ASGLFTVSAQNLPCGAS-GLTCTKALAVRLEGT----VVHMLRG 1082

Query: 516  DVLLFDQYKIIPP--YTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVE 573
              +  +   + PP  YT     +RR + +FL + T++G+ +L+D  G R+ +Q+  ++  
Sbjct: 1083 RAVTVNGVSVTPPKVYTGPGLSLRR-AGLFLLLSTHLGLTLLWDG-GTRVLVQLSPQFRG 1140

Query: 574  DTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAA 633
               GLCG F+G+  +D  S  GV E T +L  +SW+    C     G    PC ++   A
Sbjct: 1141 RVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLSPLCPE--PGDLPHPCTMNTHRA 1198

Query: 634  SYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQ----PCLCATLAHYAHLCRR 689
             ++   C  L   +F  C A + P  ++E C  DAC C       CLC+ +A YA  C R
Sbjct: 1199 GWARARCGALLQPLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADECAR 1258

Query: 690  HGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEG 749
            HG  V +R++   C+L CE  + Y  C   C  TC +   PE      G       CVEG
Sbjct: 1259 HGHHVRWRSQ-ELCSLQCEGGQVYEACGPTCPPTCHE-QHPEP-----GWHCQVVACVEG 1311

Query: 750  CACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSC 802
            C CP  T L   A  C+    C C +    +PPG       G+C C++G   C
Sbjct: 1312 CFCPEGTLLHGGA--CLEPASCPCEWGRNSFPPGSVLQKDCGNCTCQEGQWHC 1362



 Score =  214 bits (546), Expect = 7e-55
 Identities = 139/410 (33%), Positives = 195/410 (47%), Gaps = 23/410 (5%)

Query: 32   KCAPSYLFSCFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFD 91
            +C P  L  C + G+   P        N    R +  +  G  R   C+A G  H  TFD
Sbjct: 967  RCVPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFD 1026

Query: 92   GLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHL-- 149
            GL +   G   Y LV   E  G  F++   N P CG+S  TC++A+++   G   +H+  
Sbjct: 1027 GLAFTYPGACEYLLV--REASGL-FTVSAQNLP-CGASGLTCTKALAVRLEGTV-VHMLR 1081

Query: 150  AKEVTHGGMRVQLPHVMGSARLQ-QLAG-YVIVRHQSAFTLAWDGASAVYIKMSPELLGW 207
             + VT  G+ V  P V     L  + AG ++++      TL WDG + V +++SP+  G 
Sbjct: 1082 GRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGR 1141

Query: 208  THGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNP 267
              GLCG+ + D  +DL +  G L        HSW+      P  P    LP P  +  N 
Sbjct: 1142 VAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLS----PLCPEPGDLPHPCTM--NT 1195

Query: 268  GTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLC--QSMGDVATWCRALAEYARA 325
                    +C ALL+P F  CHA V P      C  D C   S GD    C A+A YA  
Sbjct: 1196 HRAGWARARCGALLQPLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADE 1255

Query: 326  CAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCH---PRASCVDSEIACVDGC 382
            CA+ G  ++ WR+Q   C++ C E    Y  C   CP +CH   P        +ACV+GC
Sbjct: 1256 CARHGHHVR-WRSQ-ELCSLQC-EGGQVYEACGPTCPPTCHEQHPEPGWHCQVVACVEGC 1312

Query: 383  YCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWEC 432
            +CP G +   G C+ PA CPCE+    +PPGSV+++DC  CTC  G+W C
Sbjct: 1313 FCPEGTLLHGGACLEPASCPCEWGRNSFPPGSVLQKDCGNCTCQEGQWHC 1362



 Score =  146 bits (369), Expect = 3e-34
 Identities = 152/516 (29%), Positives = 203/516 (39%), Gaps = 72/516 (13%)

Query: 336 WRTQLRQCT-----VHCKE---KAFTYNECIACCPASCHPRASCVDSEIACVDGCYC-PN 386
           W   +R C       HC E   KA     C A     C  +A   ++    ++ C   P 
Sbjct: 87  WNRTVRTCCPGWGGAHCTEALAKASPEGHCFAMW--QCQLQAGSANASAGSLEECCARPW 144

Query: 387 GLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDC-NTCTCTSGKWECSTAVCPAECSVTG 445
           G  + DG   A   C      + + PGS              G+         A C+   
Sbjct: 145 GQSWWDGSSQACRSC-----SSRHLPGSASSPALLQPLAGAVGQLWSQHQRPSATCASWS 199

Query: 446 DIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDP 505
             H+ TFDGR Y F   C Y+LA +  S T+ V L        Q G C Q V++      
Sbjct: 200 GFHYRTFDGRHYHFLGRCTYLLAGAADS-TWAVHLTPGD-RCPQPGHC-QRVTM------ 250

Query: 506 RRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS----SVFLRVRTNVGVRVLYDREGL 561
             +  L QAG+V +  Q  ++P     ++ +  LS      +L +   +GV V  DR G 
Sbjct: 251 GPEEVLIQAGNVSVKGQ--LVP--EGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDRTG- 305

Query: 562 RLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWK-------TLSAC 614
            + + VD      T GLCG +NG  +DDF+ P G        FGNSW+        L A 
Sbjct: 306 SISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSESGCLDAV 365

Query: 615 SPLVSGSPLDPCDV-----HLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDAC 669
                  PL   D      HL+A +  V  C  L    F  C A +SP  Y E C    C
Sbjct: 366 EVAQGCDPLGLIDADVEPGHLRAEAQDV--CHQLLEGPFGQCHAQVSPAEYHEACLFAYC 423

Query: 670 RCG---------QPCLCATLAHYAHLC-RRHGLPVDFRARLPA-CALSCEASKEYSPCVA 718
                       Q  +CAT A Y   C RRH   +  R R P  C   C   + YS CV+
Sbjct: 424 AGAMAGSGQEGRQQAVCATFASYVQACARRH---IHIRWRKPGFCERLCPGGQLYSDCVS 480

Query: 719 PCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGV 778
            C  +C      EA G  G ++  R+ECV GC CP   + +    LCVP   C C++   
Sbjct: 481 LCPPSC------EAVG-QGEEESCREECVSGCECPRGLFWN--GTLCVPAAHCPCYYCRQ 531

Query: 779 DYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAG 814
            Y PGD+       C C+DG   C      A C  G
Sbjct: 532 RYVPGDTVRQLCNPCVCRDGRWHCAQALCPAECAVG 567



 Score = 98.2 bits (243), Expect = 1e-19
 Identities = 133/533 (24%), Positives = 184/533 (34%), Gaps = 114/533 (21%)

Query: 2033 WEC-----ACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGH 2087
            W C     + RC       +VTFDG          Y+L +    + TV   +      G 
Sbjct: 1003 WHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREASGLFTVSAQNLPCGASG- 1061

Query: 2088 LNWPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPP--VSRYGFRIEDTGHMYMILT 2145
            L       V L  T + H +      R VTV+   V PP   +  G  +   G   ++ T
Sbjct: 1062 LTCTKALAVRLEGT-VVHMLR----GRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLST 1116

Query: 2146 PSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFL 2205
               + + W      ++V+ S   + +  GLCG  DGDA+NDL  + G +   AE  A   
Sbjct: 1117 HLGLTLLW-DGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAA--- 1172

Query: 2206 DSWQVPSSLTSVGQTRFRPDSC---------ATTDCSPCLRMVSNRTFSACHRFVPPESF 2256
             SW++       G     P  C         A   C   L+ +    F+ CH  VPP+  
Sbjct: 1173 HSWRLSPLCPEPGDL---PHPCTMNTHRAGWARARCGALLQPL----FTLCHAEVPPQQH 1225

Query: 2257 CELWIRDTKYVQQP------CVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSDSTYQACV 2310
             E  + D             C A+  Y   C +    + WR  + C   C     Y+AC 
Sbjct: 1226 YEWCLYDACGCDSGGDCECLCSAIATYADECARHGHHVRWRSQELCSLQCEGGQVYEACG 1285

Query: 2311 TACEPPKTCQDGILGPLDPEHCQVLG--EGCVCSEGTILHRRHSALCIPEAKCACTDSMG 2368
              C  P TC +    P    HCQV+   EGC C EGT+L   H   C+  A C C     
Sbjct: 1286 PTC--PPTCHE--QHPEPGWHCQVVACVEGCFCPEGTLL---HGGACLEPASCPC----- 1333

Query: 2369 VPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCL 2428
                    W              P +++  D G       +C               C  
Sbjct: 1334 -------EWG--------RNSFPPGSVLQKDCG-------NC--------------TCQE 1357

Query: 2429 GT-VCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCECD-PDLC------EAELVP 2480
            G   C  +   CE L P C  G  L    QE+  C  +   CD  D C      E    P
Sbjct: 1358 GQWHCGGDGGHCEELVPACAEGEALC---QENGHCVPHGWLCDNQDDCGDGSDEEGCAAP 1414

Query: 2481 SCRQDQILITGRLGDSCCTSYFC----ACGD--------CPDSIPECQEGEAL 2521
             C + Q  +T   G     +  C     CGD        CP  +  C +G  L
Sbjct: 1415 GCGEGQ--MTCSSGHCLPLALLCDRQDDCGDGTDEPSYPCPQGLLACADGRCL 1465



 Score = 85.1 bits (209), Expect = 9e-16
 Identities = 43/133 (32%), Positives = 59/133 (44%), Gaps = 10/133 (7%)

Query: 316  CRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC------CPASCHPRA 369
            C +LA     C       +   TQ   CT  C E    +     C      CP  C  + 
Sbjct: 2857 CSSLAPGDTTCPGPHSQTRDCNTQ--PCTAQCPENML-FRSAEQCHQEGGPCPRLCLTQG 2913

Query: 370  SCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKED-CNTCTCTSG 428
              ++    C  GC CP GL   +  C+  ++CPC+ HG LY  G++ + D CN CTC SG
Sbjct: 2914 PGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYASGAMARLDSCNNCTCVSG 2973

Query: 429  KWECSTAVCPAEC 441
            K  C++  CP  C
Sbjct: 2974 KMACTSERCPVAC 2986



 Score = 81.6 bits (200), Expect = 1e-14
 Identities = 96/400 (24%), Positives = 144/400 (36%), Gaps = 59/400 (14%)

Query: 1996 QLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACR----CSIFPDLSFVTFD 2051
            Q  R   S+H P  A+ P   +  LA  VG      LW    R    C+ +    + TFD
Sbjct: 154  QACRSCSSRHLPGSASSPAL-LQPLAGAVG-----QLWSQHQRPSATCASWSGFHYRTFD 207

Query: 2052 GSHVALFKEAIYILSQSPDEMLTVHVLDC-KSANLGHLNWPPFCLVMLNMTHLAHQVTID 2110
            G H        Y+L+ + D    VH+    +    GH            +T    +V I 
Sbjct: 208  GRHYHFLGRCTYLLAGAADSTWAVHLTPGDRCPQPGHCQ---------RVTMGPEEVLIQ 258

Query: 2111 RFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKA 2170
              N  V   L P       +G  ++  G  +++L+     +  L  +G + +        
Sbjct: 259  AGNVSVKGQLVPEGQSWLLHGLSLQWLGD-WLVLSGGLGVVVRLDRTGSISISVDHELWG 317

Query: 2171 QGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSC--- 2227
            Q  GLCG+ +G   +D     G   G A   A F +SW++P S +           C   
Sbjct: 318  QTQGLCGLYNGWPEDDFMEPGG---GLAMLAATFGNSWRLPGSESGCLDAVEVAQGCDPL 374

Query: 2228 --ATTDCSP----------CLRMVSNRTFSACHRFVPPESFCELWI-----------RDT 2264
                 D  P          C +++    F  CH  V P  + E  +              
Sbjct: 375  GLIDADVEPGHLRAEAQDVCHQLLEG-PFGQCHAQVSPAEYHEACLFAYCAGAMAGSGQE 433

Query: 2265 KYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGIL 2324
               Q  C     YV  C + H+ I WR+  +C  LC     Y  CV+ C  P +C+   +
Sbjct: 434  GRQQAVCATFASYVQACARRHIHIRWRKPGFCERLCPGGQLYSDCVSLC--PPSCE--AV 489

Query: 2325 GPLDPEHC-QVLGEGCVCSEGTILHRRHSALCIPEAKCAC 2363
            G  + E C +    GC C  G      +  LC+P A C C
Sbjct: 490  GQGEEESCREECVSGCECPRGLFW---NGTLCVPAAHCPC 526



 Score = 73.9 bits (180), Expect = 2e-12
 Identities = 42/129 (32%), Positives = 60/129 (46%), Gaps = 14/129 (10%)

Query: 323  ARACAQ-----AGRPLQGWRTQLRQCT-VHCKEKAFTYNECIAC---CPASCHPRAS--- 370
            +R+C+       G P  G R Q R C  + C+       E + C   CP  C        
Sbjct: 4028 SRSCSSPPSKNGGAPCAGERHQARLCNPMPCEAGCPAGMEVVTCANRCPRRCSDLQEGIV 4087

Query: 371  CVDSEIACVDGCYCPNGLIFEDGGCVAPAECPC-EFHGTLYPPGSVVKEDCNTCTCTSGK 429
            C D ++ C  GC CP G + +DGGCV    C C +  G  + PGS  ++ CN C+C +G+
Sbjct: 4088 CQDDQV-CQKGCRCPKGSLEQDGGCVPIGHCDCTDAQGHSWAPGSQHQDACNNCSCQAGQ 4146

Query: 430  WECSTAVCP 438
              C+   CP
Sbjct: 4147 LSCTAQPCP 4155



 Score = 72.4 bits (176), Expect = 6e-12
 Identities = 97/423 (22%), Positives = 136/423 (32%), Gaps = 146/423 (34%)

Query: 606  NSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCR 665
            + W   S C P +  S L P      A+  +++   +      +P    L+P+   EQ R
Sbjct: 4526 SEWSEWSPCGPCLPPSALAP------ASRTALEEHWLRDPTGLSPT---LAPLLASEQHR 4576

Query: 666  RDACR--------CGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASK--EYSP 715
               C          G P LC        LC   G          AC  SC+ S    +SP
Sbjct: 4577 HRLCLDPATGRPWTGAPHLCTAPLSQQRLCPDPG----------ACPDSCQWSLWGPWSP 4626

Query: 716  CVAPC---------------GRTCQDLASPEACGVDGG---------------------- 738
            C  PC               G  C++  + E+C  +GG                      
Sbjct: 4627 CQVPCSGGFRLRWREAEALCGGGCREPWAQESC--NGGPCPECEAQDTVFTLDCANQCPH 4684

Query: 739  ---DDLSRDECVEG-----CACPPDTYLDTQADLCVPRNQCSCHFQGV----DYPPGDSD 786
               D   R +C++G     C CPP   +  Q   CVP + C C         +  P  + 
Sbjct: 4685 SCADLWDRVQCLQGPCRPGCRCPPGQLV--QDGRCVPISSCRCGLPSANASWELAPAQAV 4742

Query: 787  IPSLGHCHCKDGVMSCDSRAPAAACPA---GQVFVNCSDLHTDLELSRERTCE------- 836
                 +C C +  + C    P   CP       + +CS       + R RTCE       
Sbjct: 4743 QLDCQNCTCVNESLVC----PHQECPVLGPWSAWSSCSAPCGGGTMERHRTCEGGPGVAP 4798

Query: 837  --------QQLLNL-----------------------------SVSARGPCLSGCACPQG 859
                    +Q  NL                             ++  + PC  GC CP G
Sbjct: 4799 CQAQDTEQRQECNLQPCPECPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGG 4858

Query: 860  LLRHGDACFLPEECPCT-----W--------KGKEYFPGDQVMSPCHTCVCQRGSFQCTL 906
             L H   C  P  CPCT     W        + +E  PG  +   C  CVC  G+F C+L
Sbjct: 4859 QLLHNGTCVPPTACPCTQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSL 4918

Query: 907  HPC 909
              C
Sbjct: 4919 VDC 4921



 Score = 70.9 bits (172), Expect = 2e-11
 Identities = 30/78 (38%), Positives = 41/78 (52%), Gaps = 6/78 (7%)

Query: 362  PASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCN 421
            PASC   ++   +   C  GC+CP+G++  +  CV   +CPC   G LYPPGS V   C 
Sbjct: 3103 PASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCAHEGHLYPPGSTVVRPCE 3162

Query: 422  TCTCTSG------KWECS 433
             C+C SG       W C+
Sbjct: 3163 NCSCVSGLIANCSSWPCA 3180



 Score = 70.9 bits (172), Expect = 2e-11
 Identities = 54/221 (24%), Positives = 72/221 (32%), Gaps = 28/221 (12%)

Query: 707  CEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCV 766
            C   +  S C   C   C  L     C         ++ C  GC CP    L      CV
Sbjct: 4818 CPPGQVLSACATSCPCLCWHLQPGAIC--------VQEPCQPGCGCPGGQLLHNGT--CV 4867

Query: 767  PRNQCSC-------------HFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPA 813
            P   C C               Q  + PPG     +   C C  G  SC         P 
Sbjct: 4868 PPTACPCTQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCS--LVDCQVPP 4925

Query: 814  GQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEE- 872
            G+ +   +    +L L  +   E        +      SGC C  G  R      +PE+ 
Sbjct: 4926 GETWQQVAP--GELGLCEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDH 4983

Query: 873  CPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPCASTC 913
            C C   G+ + PG +    C +C+C  G   CT H    TC
Sbjct: 4984 CECWHLGRPHLPGSEWQEACESCLCLSGRPVCTQHCSPLTC 5024



 Score = 70.1 bits (170), Expect = 3e-11
 Identities = 89/374 (23%), Positives = 143/374 (38%), Gaps = 65/374 (17%)

Query: 845  SARGPCLSGCACP-QGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQR---- 899
            S  G C +   C  Q    +  A  L E C   W G+ ++ G      C +C  +     
Sbjct: 111  SPEGHCFAMWQCQLQAGSANASAGSLEECCARPW-GQSWWDGSS--QACRSCSSRHLPGS 167

Query: 900  GSFQCTLHPCA--------------STCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD 945
             S    L P A              +TC ++   HYRTFDG  + F+G C  +L+   +D
Sbjct: 168  ASSPALLQPLAGAVGQLWSQHQRPSATCASWSGFHYRTFDGRHYHFLGRC-TYLLAGAAD 226

Query: 946  VSFSV-IVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVG 1004
             +++V +     C   G   R    + +G   ++    +GN S +  L    E  +W + 
Sbjct: 227  STWAVHLTPGDRCPQPGHCQR----VTMGPEEVLI--QAGNVSVKGQL--VPEGQSWLLH 278

Query: 1005 FFT-------LVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPE 1057
              +       LV      + +  D+  ++ +    +  GQ  GLCG ++    ++   P 
Sbjct: 279  GLSLQWLGDWLVLSGGLGVVVRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPG 338

Query: 1058 NLELTNPQEFGSSWA----------AVECPDTLDPRDMCVLNPLREP-----FAKKECSI 1102
                     FG+SW           AVE     DP  + +++   EP      A+  C  
Sbjct: 339  GGLAMLAATFGNSWRLPGSESGCLDAVEVAQGCDP--LGLIDADVEPGHLRAEAQDVCHQ 396

Query: 1103 LLSEVFEICHPVVDVTWFYSNCLTDTC-----GCSQGGDCECFCASVSAYAHQCCQHGVA 1157
            LL   F  CH  V    ++  CL   C     G  Q G  +  CA+ ++Y   C +  + 
Sbjct: 397  LLEGPFGQCHAQVSPAEYHEACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIH 456

Query: 1158 VDWRTP----RLCP 1167
            + WR P    RLCP
Sbjct: 457  IRWRKPGFCERLCP 470



 Score = 70.1 bits (170), Expect = 3e-11
 Identities = 65/239 (27%), Positives = 89/239 (37%), Gaps = 50/239 (20%)

Query: 241  WQEQAPNQPP--GPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFT 298
            W E      P  G T S      C     G      E  EA  +   +AC +Y       
Sbjct: 3414 WSEWTMCSQPCRGQTRSRSRACACPTPQHGGAPCTGEAGEAGAQHQREACPSY------- 3466

Query: 299  ASCTSDLCQSMGDVATW-----CRALAEYARACA-----QAGRPLQGWRTQLRQC---TV 345
            A+C  D   + G    W     C   +  +RAC+     + GRP  G  TQ R C   + 
Sbjct: 3467 ATCPVD--GAWGPWGPWSPCDMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENST 3524

Query: 346  HCKE--KAFTYNECIACCPASCH---PRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE 400
             C +     + + C   CP SC    P + C    + C   C CP G + +DG CV PA 
Sbjct: 3525 QCTDCGGGQSLHPCGQPCPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAH 3584

Query: 401  CPCEFH--------------GTLY------PPGSVVKEDCNTCTCTSGKWECSTAV-CP 438
            C C++               G+ +       PG VV   C+ CTC +G  +C     CP
Sbjct: 3585 CRCQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCP 3643



 Score = 70.1 bits (170), Expect = 3e-11
 Identities = 49/166 (29%), Positives = 61/166 (36%), Gaps = 31/166 (18%)

Query: 301  CTSDLCQSMGDVATWCRALA-------EYARAC--AQAGRPLQGWRTQLRQ-CTVH-CKE 349
            C    C  +G  + W    A       E  R C       P Q   T+ RQ C +  C E
Sbjct: 4758 CPHQECPVLGPWSAWSSCSAPCGGGTMERHRTCEGGPGVAPCQAQDTEQRQECNLQPCPE 4817

Query: 350  --KAFTYNECIACCPASC---HPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCE 404
                   + C   CP  C    P A CV     C  GC CP G +  +G CV P  CPC 
Sbjct: 4818 CPPGQVLSACATSCPCLCWHLQPGAICVQEP--CQPGCGCPGGQLLHNGTCVPPTACPCT 4875

Query: 405  FHGTLY-------------PPGSVVKEDCNTCTCTSGKWECSTAVC 437
             H   +             PPG+V+  +C  C C  G + CS   C
Sbjct: 4876 QHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDC 4921



 Score = 69.7 bits (169), Expect = 4e-11
 Identities = 55/208 (26%), Positives = 73/208 (35%), Gaps = 19/208 (9%)

Query: 716  CVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHF 775
            C+AP G       S   C   G      D   E    PP   + +   L  P + CS   
Sbjct: 2788 CLAPGGGPGWRSRS-RLCPSPGDSSCPGDATQEEPCSPPVCPVPSIWGLWAPWSTCSAPC 2846

Query: 776  QG---------VDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTD 826
             G             PGD+  P   H   +D    C+++   A CP   +F +    H +
Sbjct: 2847 DGGIQTRGRSCSSLAPGDTTCPG-PHSQTRD----CNTQPCTAQCPENMLFRSAEQCHQE 2901

Query: 827  LELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGD 886
                  R C  Q     +   G C  GC CP GL  H  +C    +CPC   G+ Y  G 
Sbjct: 2902 GGPC-PRLCLTQ--GPGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYASGA 2958

Query: 887  QV-MSPCHTCVCQRGSFQCTLHPCASTC 913
               +  C+ C C  G   CT   C   C
Sbjct: 2959 MARLDSCNNCTCVSGKMACTSERCPVAC 2986



 Score = 68.9 bits (167), Expect = 7e-11
 Identities = 69/260 (26%), Positives = 85/260 (32%), Gaps = 67/260 (25%)

Query: 700  LPACALSCEASK--EYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTY 757
            LP    +C A +  EYSPC  PC R+C DL                  C  GC CPP   
Sbjct: 3304 LPCPVTNCTAIEGAEYSPCGPPCPRSCDDLVHCVW------------RCQPGCYCPPGQV 3351

Query: 758  LDTQADLCVPRNQCSC--HFQGVDYPPGD--SDIPSLGHCHCKDGVMSCDS---RAPAAA 810
            L +   +CV    CSC     G  + PG   +      HC C +G ++C       P   
Sbjct: 3352 LSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGRLNCTDLPCPVPGGW 3411

Query: 811  CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLP 870
            CP  + +  CS        SR R C             PC +G A   G     +AC   
Sbjct: 3412 CPWSE-WTMCSQPCRGQTRSRSRAC---ACPTPQHGGAPC-TGEAGEAGAQHQREACPSY 3466

Query: 871  EECPCTWKGKEYFPGDQVMSPCHTCV------------------------------CQRG 900
              CP       + P     SPC  C+                              CQ  
Sbjct: 3467 ATCPVDGAWGPWGP----WSPCDMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQEN 3522

Query: 901  SFQCT-------LHPCASTC 913
            S QCT       LHPC   C
Sbjct: 3523 STQCTDCGGGQSLHPCGQPC 3542



 Score = 68.9 bits (167), Expect = 7e-11
 Identities = 56/208 (26%), Positives = 80/208 (38%), Gaps = 31/208 (14%)

Query: 258  PRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATW-- 315
            P  PC +     +      C  L+      C++    L  T  C S  C      ++W  
Sbjct: 4315 PWGPCSRSCGPGLASRSGSCPCLMAKADPTCNSTFLHLD-TQGCYSGPCPEECVWSSWSS 4373

Query: 316  -----CRALAEY-------ARACAQAGRPLQGWRTQLRQCTV-HCKEKA----FTYNECI 358
                 CR L +        A   A+AG P        R C + +C E +    F ++ C 
Sbjct: 4374 WTRCSCRVLVQQRYRHQGPASRGARAGAPCTRLDGHFRPCLISNCSEDSCTPPFEFHACG 4433

Query: 359  ACCPASCHPRAS---CVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFH------GTL 409
            + C   C    S   C D    C  GCYCP GL+ + GGC+ P EC C +H      G  
Sbjct: 4434 SPCAGLCATHLSHQLCQDLP-PCQPGCYCPKGLLEQAGGCIPPEECNC-WHTSAAGAGMT 4491

Query: 410  YPPGSVVKEDCNTCTCTSGKWECSTAVC 437
              PG  ++  C  C C  G+  C++  C
Sbjct: 4492 LAPGDRLQLGCKECECRRGELHCTSQGC 4519



 Score = 66.6 bits (161), Expect = 3e-10
 Identities = 131/556 (23%), Positives = 193/556 (34%), Gaps = 101/556 (18%)

Query: 1957 LSIVEGLAEALATTTEANTSTTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCG 2016
            +S+     EA+    E +    CV   E  C R +   G L     + HCP      R  
Sbjct: 479  VSLCPPSCEAVGQGEEESCREECVSGCE--CPRGLFWNGTLCV--PAAHCPCYYCRQRY- 533

Query: 2017 ILGLAVRVGGDRCC---PLWECA-----CRCSIFPDLSFVTFDGSHVALF--KEAIYILS 2066
            + G  VR   + C      W CA       C++  D  ++TFDG   + +  +   Y L 
Sbjct: 534  VPGDTVRQLCNPCVCRDGRWHCAQALCPAECAVGGDGHYLTFDGRSYSFWGGQGCRYSLV 593

Query: 2067 QSPDEMLTVHVLDCKSANLGHLNWPPFCL----VMLNMTHLAHQVTIDRFNRKVTVDLQP 2122
            Q   +   + +L+  + + G       CL    V L  TH+       R +  V V+ Q 
Sbjct: 594  QDYVKGQLLILLEHGACDAGS------CLHAISVSLEDTHIQL-----RDSGAVLVNGQD 642

Query: 2123 VWPP-VSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDG 2181
            V  P +   G  +      +++L     Q+ W  S  +  +        Q  GLCG    
Sbjct: 643  VGLPWIGAEGLSVRRASSAFLLLRWPGAQVLWGLSDPVAYITLDPRHAHQVQGLCGTFTQ 702

Query: 2182 DAANDLTLKDGSVVGGAEDPAPFLDSWQVP---------SSLTSVGQTRFRPDSCATTDC 2232
            +  +D     G V       A F   +QV          S+L S   T  +  + A   C
Sbjct: 703  NQQDDFLTPAGDVETSI---AAFASKFQVAGKGRCPSEDSALLSPCTTHSQRHAFAEAAC 759

Query: 2233 SPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYV-------QQPCVALTVYVAMCHKFH 2285
            +    ++ +  F  CHR V  E F   ++R    V          C  L+ Y   C +  
Sbjct: 760  A----ILHSSVFQECHRLVDKEPF---YLRCLAAVCGCDPGSDCLCPVLSAYARRCAQEG 812

Query: 2286 VCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGE---GCVCS 2342
                WR    CP +C     Y+ C  AC   + C         PE C  LG    GC C 
Sbjct: 813  ASPPWRNQTLCPVMCPGGQEYRECAPAC--GQHCG-------KPEDCGELGSCVAGCNCP 863

Query: 2343 EGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGC 2402
             G +        C+P + C C   +G  R      ++++  C +  CQ           C
Sbjct: 864  LGLLWD--PEGQCVPPSLCPC--QLGARRY--APGSATMKECNRCICQERGLWNCTARHC 917

Query: 2403 PS----PRPESCLRFGEVALLLPTKDP-----CCLGTVCVCNQTLCEGLAPTCRPGHRLL 2453
            PS    PR    L +   A LL    P     C  G+   C           C PG  LL
Sbjct: 918  PSQAFCPRE---LVYAPGACLLTCDSPSANHSCPAGSTDGC----------VCPPGTVLL 964

Query: 2454 THFQEDSCCPSYSCEC 2469
                ++ C P   C C
Sbjct: 965  ----DERCVPPDLCPC 976



 Score = 66.6 bits (161), Expect = 3e-10
 Identities = 78/351 (22%), Positives = 107/351 (30%), Gaps = 125/351 (35%)

Query: 674  PC-LCATLAHYAHLCRRHGLPVDFR------ARLPAC------ALSCEASKEYSPCVAPC 720
            PC +C   +H +  C R   P   R       +   C         C   +   PC  PC
Sbjct: 3483 PCDMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTDCGGGQSLHPCGQPC 3542

Query: 721  GRTCQDLASPEAC--GVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQ-- 776
             R+CQDL+    C  G  G        C   C CP      +Q  LCVP   C C +Q  
Sbjct: 3543 PRSCQDLSPGSVCQPGSVG--------CQPTCGCPLGQL--SQDGLCVPPAHCRCQYQPG 3592

Query: 777  --GV----------------DYPPGDSDIPSLGHCHCKDGVMSCD--------------- 803
              G+                   PG+       +C C  G++ C                
Sbjct: 3593 AMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCPDPGVWSSWG 3652

Query: 804  --------------------SRAPA-----------------AACPAGQVFVNCSDLHTD 826
                                +R P                  A CPAG+++  C      
Sbjct: 3653 PWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCSTQVCREAGCPAGRLYRECQPGE-- 3710

Query: 827  LELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPC---TW------ 877
                   +C      +   + G C  GC CP+G  +H  AC   +ECPC    W      
Sbjct: 3711 ---GCPFSCAHVTQQVGCFSEG-CEEGCHCPEGTFQHRLACV--QECPCVLTAWLLQELG 3764

Query: 878  -----KGKEYFPGDQVMS------PCHTCVCQRGSFQCTLHPCASTCTAYG 917
                  G+   PGD++ S       C  C C  G   C+L  C      +G
Sbjct: 3765 ATIGDPGQPLGPGDELDSGQTLRTSCGNCSCAHGKLSCSLDDCFEADGGFG 3815



 Score = 64.7 bits (156), Expect = 1e-09
 Identities = 39/128 (30%), Positives = 51/128 (39%), Gaps = 12/128 (9%)

Query: 317  RALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEI 376
            + L +Y       G   Q     +  CT     +   Y+ C   CP SC     CV    
Sbjct: 3285 QGLGDYCEGPRAQGEVCQALPCPVTNCTAI---EGAEYSPCGPPCPRSCDDLVHCV---W 3338

Query: 377  ACVDGCYCPNGLIFEDGG--CVAPAECPCE--FHGTLYPPGSVVK--EDCNTCTCTSGKW 430
             C  GCYCP G +    G  CV P  C C     G  + PG+ +   + CN CTC  G+ 
Sbjct: 3339 RCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGRL 3398

Query: 431  ECSTAVCP 438
             C+   CP
Sbjct: 3399 NCTDLPCP 3406



 Score = 64.3 bits (155), Expect = 2e-09
 Identities = 34/109 (31%), Positives = 42/109 (38%), Gaps = 8/109 (7%)

Query: 802  CDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLL 861
            C+     A CPAG   V C++          R C      +       C  GC CP+G L
Sbjct: 4053 CNPMPCEAGCPAGMEVVTCAN-------RCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSL 4105

Query: 862  RHGDACFLPEECPCT-WKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPC 909
                 C     C CT  +G  + PG Q    C+ C CQ G   CT  PC
Sbjct: 4106 EQDGGCVPIGHCDCTDAQGHSWAPGSQHQDACNNCSCQAGQLSCTAQPC 4154



 Score = 63.9 bits (154), Expect = 2e-09
 Identities = 42/139 (30%), Positives = 55/139 (39%), Gaps = 8/139 (5%)

Query: 778  VDYPP--GDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTC 835
            VD PP  G +  P         G+  C        C  G+V+V+       L      +C
Sbjct: 2583 VDPPPKNGGAPCPGASQERAPCGLQPCSG---GTDCELGRVYVSADLCQKGLVPPCPPSC 2639

Query: 836  EQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPG-DQVMSPCHT 894
                 N S S  G C+ GC CP GLL H   C    ECPC    +  +PG   ++  C  
Sbjct: 2640 LDPKANRSCS--GHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLGNCSQ 2697

Query: 895  CVCQRGSFQCTLHPCASTC 913
            CVC++G   C    C   C
Sbjct: 2698 CVCEKGELLCQPGGCPLPC 2716



 Score = 62.4 bits (150), Expect = 6e-09
 Identities = 56/203 (27%), Positives = 73/203 (35%), Gaps = 39/203 (19%)

Query: 258  PRPPCLQQNPGTMQGVYEQCEALLRPPFDACHA--YVSPLPFTASCTSDLCQSMGDVATW 315
            P  PC +      QG   +C  L       C    + S   FTA+C  D     G+ +TW
Sbjct: 1702 PWGPCSRTCGPWGQGRSRRCSPLGLLVLQNCPGPEHQSQACFTAACPVD-----GEWSTW 1756

Query: 316  ---------CRALAEYARACAQAGRPLQGWRT------------QLRQCTVHCKEKAFTY 354
                     CR      R C     P  G RT            Q + C       A   
Sbjct: 1757 SPWSVCSEPCRGTMTRQRQCHS---PQNGGRTCAALPGGLHSTRQTKPCPQDGCPNATCS 1813

Query: 355  NECI----ACCPASCHP---RASCVDSEIACVDGCYCPNGLIF-EDGGCVAPAECPCEFH 406
             E +    A CP +C     + +C         GC+CP G +   +G CV P +CPC   
Sbjct: 1814 GELMFQPCAPCPLTCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSEGWCVWPRQCPCLVD 1873

Query: 407  GTLYPPGSVVKEDCNTCTCTSGK 429
            G  Y PG  +K DC  C C  G+
Sbjct: 1874 GARYWPGQRIKADCQLCICQDGR 1896



 Score = 62.4 bits (150), Expect = 6e-09
 Identities = 34/85 (40%), Positives = 43/85 (50%), Gaps = 7/85 (8%)

Query: 361  CPASC-HPRA--SCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPG-SVV 416
            CP SC  P+A  SC      CV+GC CP GL+  D  C+  +ECPC     L  PG S +
Sbjct: 2635 CPPSCLDPKANRSCSGH---CVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFL 2691

Query: 417  KEDCNTCTCTSGKWECSTAVCPAEC 441
              +C+ C C  G+  C    CP  C
Sbjct: 2692 LGNCSQCVCEKGELLCQPGGCPLPC 2716



 Score = 62.0 bits (149), Expect = 8e-09
 Identities = 36/115 (31%), Positives = 49/115 (42%), Gaps = 14/115 (12%)

Query: 798  GVMSCDSRAPAAACPAGQVFVNCSDLHTDL-ELSRERTCEQQLLNLSVSARGPCLSGCAC 856
            G+  C    P   CP  + +++C+       ELS  R   Q            C  GC C
Sbjct: 3078 GLQPCAGPVPGM-CPRDKQWLDCAQGPASCAELSAPRGTNQT-----------CHPGCHC 3125

Query: 857  PQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSF-QCTLHPCA 910
            P G+L   + C   ++CPC  +G  Y PG  V+ PC  C C  G    C+  PCA
Sbjct: 3126 PSGMLLLNNVCVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPCA 3180



 Score = 61.6 bits (148), Expect = 1e-08
 Identities = 27/66 (40%), Positives = 31/66 (46%), Gaps = 5/66 (7%)

Query: 849  PCLSGCACPQGLLRHGDACFLPEECPC-----TWKGKEYFPGDQVMSPCHTCVCQRGSFQ 903
            PC  GC CP+GLL     C  PEEC C        G    PGD++   C  C C+RG   
Sbjct: 4454 PCQPGCYCPKGLLEQAGGCIPPEECNCWHTSAAGAGMTLAPGDRLQLGCKECECRRGELH 4513

Query: 904  CTLHPC 909
            CT   C
Sbjct: 4514 CTSQGC 4519



 Score = 60.5 bits (145), Expect = 2e-08
 Identities = 62/231 (26%), Positives = 83/231 (35%), Gaps = 38/231 (16%)

Query: 707  CEASKEYSPCVAPCGRTCQDLASPEA--CGVDG--------GDDLSRDECVEGCACPPDT 756
            C A   +SP   PC RTC       +  C   G        G +     C    ACP D 
Sbjct: 1694 CGAWGPWSPW-GPCSRTCGPWGQGRSRRCSPLGLLVLQNCPGPEHQSQACFTA-ACPVDG 1751

Query: 757  YLDTQADLCVPRNQC--------SCHFQGVDYPPGDSDIPSL-GHCHCKDGVMSC-DSRA 806
               T +   V    C         CH        G     +L G  H       C     
Sbjct: 1752 EWSTWSPWSVCSEPCRGTMTRQRQCHSP----QNGGRTCAALPGGLHSTRQTKPCPQDGC 1807

Query: 807  PAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLS-GCACPQGLLRHGD 865
            P A C    +F  C+            TC+     ++     PC S GC CP+G +   +
Sbjct: 1808 PNATCSGELMFQPCAPCPL--------TCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSE 1859

Query: 866  A-CFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG-SFQCTLHP-CASTC 913
              C  P +CPC   G  Y+PG ++ + C  C+CQ G   +C L+P CA  C
Sbjct: 1860 GWCVWPRQCPCLVDGARYWPGQRIKADCQLCICQDGRPRRCRLNPDCAVDC 1910



 Score = 58.2 bits (139), Expect = 1e-07
 Identities = 42/137 (30%), Positives = 51/137 (37%), Gaps = 25/137 (18%)

Query: 677  CATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVD 736
            CA   H A LC  + +P         C   C A  E   C   C R C DL     C  D
Sbjct: 4043 CAGERHQARLC--NPMP---------CEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDD 4091

Query: 737  GGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSC-HFQGVDYPPGDSDIPSLGHCHC 795
                     C +GC CP  +    Q   CVP   C C   QG  + PG     +  +C C
Sbjct: 4092 -------QVCQKGCRCPKGSL--EQDGGCVPIGHCDCTDAQGHSWAPGSQHQDACNNCSC 4142

Query: 796  KDGVMSCDSRAPAAACP 812
            + G +SC     A  CP
Sbjct: 4143 QAGQLSC----TAQPCP 4155



 Score = 53.9 bits (128), Expect = 2e-06
 Identities = 29/90 (32%), Positives = 36/90 (40%), Gaps = 9/90 (10%)

Query: 356  ECIACCPASCHP---RASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGT---- 408
            +C   CP SC     R  C+     C  GC CP G + +DG CV  + C C         
Sbjct: 4677 DCANQCPHSCADLWDRVQCLQGP--CRPGCRCPPGQLVQDGRCVPISSCRCGLPSANASW 4734

Query: 409  LYPPGSVVKEDCNTCTCTSGKWECSTAVCP 438
               P   V+ DC  CTC +    C    CP
Sbjct: 4735 ELAPAQAVQLDCQNCTCVNESLVCPHQECP 4764



 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 85/323 (26%), Positives = 111/323 (34%), Gaps = 81/323 (25%)

Query: 2296 CPFLCSSDSTYQACVTACEPPKTC---QDGILGPLDPEHCQVLGEGCVCSEGTILHRRHS 2352
            CP  C       AC T+C  P  C   Q G +   +P  CQ    GC C  G +LH   +
Sbjct: 4815 CPE-CPPGQVLSACATSC--PCLCWHLQPGAICVQEP--CQ---PGCGCPGGQLLH---N 4863

Query: 2353 ALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVP--------------- 2397
              C+P   C CT    +P      W  +L+   Q Q   P T++                
Sbjct: 4864 GTCVPPTACPCTQH-SLP------WGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSC 4916

Query: 2398 --VDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPT---CRPGHRL 2452
              VD   P       +  GE+ L   T    CL       Q+ C     +   C+PGH  
Sbjct: 4917 SLVDCQVPPGETWQQVAPGELGLCEQT----CLEMNATKTQSNCSSARASGCVCQPGH-- 4970

Query: 2453 LTHFQEDSCCPSYSCEC----DPDL--------CEAELV----PSCRQDQILITGRLGDS 2496
                Q   C P   CEC     P L        CE+ L     P C Q    +T   G+ 
Sbjct: 4971 -FRSQAGPCVPEDHCECWHLGRPHLPGSEWQEACESCLCLSGRPVCTQHCSPLTCAQGEE 5029

Query: 2497 CCTSYFCACGDCPDSIPECQEG--EALTVHRNTTELCCPLYQ---CVCENFRCPQVQCGL 2551
                    C  C    PE Q    + LT  RN T+  C L Q     C  +      C  
Sbjct: 5030 MVLEPGSCCPSCRREAPEEQSPSCQLLTELRNFTKGTCYLDQVEVSYCSGY------CPS 5083

Query: 2552 GTALVEVWSPDRCCPYKSCECDC 2574
             T ++    P+   PY   +CDC
Sbjct: 5084 STHVM----PEE--PYLQSQCDC 5100



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 42/143 (29%), Positives = 52/143 (36%), Gaps = 32/143 (22%)

Query: 323  ARACAQAGRPLQGWRTQLRQCTVH-CKEKAFT----YNECIAC--CPASC-HPRASCVDS 374
            +R CA+   P  G   Q R C+   C+E        Y EC     CP SC H        
Sbjct: 3669 SRRCARP--PCPGPARQSRTCSTQVCREAGCPAGRLYRECQPGEGCPFSCAHVTQQVGCF 3726

Query: 375  EIACVDGCYCPNGLIFEDGGCVAPAECPC--------EFHGTLYPPGS------------ 414
               C +GC+CP G       CV   ECPC        E   T+  PG             
Sbjct: 3727 SEGCEEGCHCPEGTFQHRLACVQ--ECPCVLTAWLLQELGATIGDPGQPLGPGDELDSGQ 3784

Query: 415  VVKEDCNTCTCTSGKWECSTAVC 437
             ++  C  C+C  GK  CS   C
Sbjct: 3785 TLRTSCGNCSCAHGKLSCSLDDC 3807



 Score = 49.3 bits (116), Expect = 5e-05
 Identities = 29/103 (28%), Positives = 45/103 (43%), Gaps = 12/103 (11%)

Query: 707  CEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCV 766
            C   K++  C A    +C +L++P           +   C  GC CP    L    ++CV
Sbjct: 3090 CPRDKQWLDC-AQGPASCAELSAPRG---------TNQTCHPGCHCPSGMLLLN--NVCV 3137

Query: 767  PRNQCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAA 809
            P   C C  +G  YPPG + +    +C C  G+++  S  P A
Sbjct: 3138 PTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPCA 3180



 Score = 48.9 bits (115), Expect = 7e-05
 Identities = 33/115 (28%), Positives = 44/115 (38%), Gaps = 14/115 (12%)

Query: 706  SCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLC 765
            SC    E+  C +PC   C    S + C      DL    C  GC CP    L  QA  C
Sbjct: 4422 SCTPPFEFHACGSPCAGLCATHLSHQLC-----QDL--PPCQPGCYCPKG--LLEQAGGC 4472

Query: 766  VPRNQCSCHF-----QGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQ 815
            +P  +C+C        G+   PGD        C C+ G + C S+      P  +
Sbjct: 4473 IPPEECNCWHTSAAGAGMTLAPGDRLQLGCKECECRRGELHCTSQGCQGLLPLSE 4527



 Score = 47.8 bits (112), Expect = 2e-04
 Identities = 71/335 (21%), Positives = 109/335 (32%), Gaps = 70/335 (20%)

Query: 608  WKTLSACSPLVSGSPLD------------PCDVH--LQAASYSVQACSVLT-GEMFAPCS 652
            W   S+CS    G  ++            PC      Q    ++Q C     G++ + C+
Sbjct: 4769 WSAWSSCSAPCGGGTMERHRTCEGGPGVAPCQAQDTEQRQECNLQPCPECPPGQVLSACA 4828

Query: 653  AFLSPVPYFEQ----CRRDACRCGQPCLCATLAHY-------AHLCRRHGLPVDFRARL- 700
                 + +  Q    C ++ C+ G  C    L H        A  C +H LP      L 
Sbjct: 4829 TSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTACPCTQHSLPWGLTLTLE 4888

Query: 701  -------PACALSCEASK----------EYSPCVAPCGRTCQDLASPE------ACGVDG 737
                   P   L+   ++              C  P G T Q +A  E       C ++ 
Sbjct: 4889 EQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQVPPGETWQQVAPGELGLCEQTC-LEM 4947

Query: 738  GDDLSRDEC----VEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHC 793
                ++  C      GC C P  +  +QA  CVP + C C   G  + PG     +   C
Sbjct: 4948 NATKTQSNCSSARASGCVCQPG-HFRSQAGPCVPEDHCECWHLGRPHLPGSEWQEACESC 5006

Query: 794  HCKDGVMSCDSRAPAAACPAGQVFV-----NCSDLHTDLELSRERTCEQQLLNLSVSARG 848
             C  G   C        C  G+  V      C     +    +  +C Q L  L    +G
Sbjct: 5007 LCLSGRPVCTQHCSPLTCAQGEEMVLEPGSCCPSCRREAPEEQSPSC-QLLTELRNFTKG 5065

Query: 849  PC------LSGCA--CPQGLLRHGDACFLPEECPC 875
             C      +S C+  CP       +  +L  +C C
Sbjct: 5066 TCYLDQVEVSYCSGYCPSSTHVMPEEPYLQSQCDC 5100



 Score = 46.6 bits (109), Expect = 4e-04
 Identities = 54/201 (26%), Positives = 66/201 (32%), Gaps = 46/201 (22%)

Query: 750  CACPPDTYLDTQADLCVPRNQ---CS--------CHFQGVDYPPGDSDIPSLGHCH--CK 796
            CA  P     T A L +P      CS        C  QG D   G        HC   C 
Sbjct: 3210 CARSPSAVPSTVAPLPLPATPTPLCSGPEAEEEPCLLQGCDRAGGWGPWGPWSHCSRSCG 3269

Query: 797  DGVMS----CDSRAP------------------AAACPAGQVFVNCSDLHTDLELSRERT 834
             G+ S    CD   P                  A  CP      NC+ +           
Sbjct: 3270 GGLRSRTRACDQPPPQGLGDYCEGPRAQGEVCQALPCPV----TNCTAIEGAEYSPCGPP 3325

Query: 835  CEQQLLNLSVSARGPCLSGCACPQG--LLRHGDACFLPEECPCT--WKGKEYFPGDQVMS 890
            C +   +L V     C  GC CP G  L  +G  C  P  C C     G+ + PG ++  
Sbjct: 3326 CPRSCDDL-VHCVWRCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLAR 3384

Query: 891  P--CHTCVCQRGSFQCTLHPC 909
            P  C+ C C  G   CT  PC
Sbjct: 3385 PDGCNHCTCLEGRLNCTDLPC 3405



 Score = 45.4 bits (106), Expect = 8e-04
 Identities = 57/226 (25%), Positives = 77/226 (34%), Gaps = 36/226 (15%)

Query: 2296 CPFLCSSDSTYQACVTACEPPKTC---QDGILGPLDPEHCQVLGEGCVCSEGTILHRRHS 2352
            C   C +      C   C  P+ C   Q+GI+   D    QV  +GC C +G++      
Sbjct: 4058 CEAGCPAGMEVVTCANRC--PRRCSDLQEGIVCQDD----QVCQKGCRCPKGSL---EQD 4108

Query: 2353 ALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGC---PSPRPES 2409
              C+P   C CTD+ G   A G     + + C    CQA        L C   P P P  
Sbjct: 4109 GGCVPIGHCDCTDAQGHSWAPGSQHQDACNNC---SCQAG------QLSCTAQPCPPPTH 4159

Query: 2410 CLRFGEVALLLPTKDPC-CLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCE 2468
            C  +   +   P    C   G       +     AP CR          +   CP  SC 
Sbjct: 4160 C-AWSHWSAWSPCSHSCGPRGQQSRFRSSTSGSWAPECREEQ------SQSQPCPQPSC- 4211

Query: 2469 CDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPE 2514
              P LC  +   S       + G      CT     C D   ++PE
Sbjct: 4212 --PPLC-LQGTRSRTLGDSWLQGECQRCSCTPEGVICEDTECAVPE 4254



 Score = 44.7 bits (104), Expect = 0.001
 Identities = 23/67 (34%), Positives = 30/67 (44%), Gaps = 1/67 (1%)

Query: 377  ACVDGCYC-PNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTA 435
            A   GC C P     + G CV    C C   G  + PGS  +E C +C C SG+  C+  
Sbjct: 4959 ARASGCVCQPGHFRSQAGPCVPEDHCECWHLGRPHLPGSEWQEACESCLCLSGRPVCTQH 5018

Query: 436  VCPAECS 442
              P  C+
Sbjct: 5019 CSPLTCA 5025



 Score = 43.1 bits (100), Expect = 0.004
 Identities = 26/88 (29%), Positives = 40/88 (45%), Gaps = 14/88 (15%)

Query: 717  VAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYL-DTQADLCVPRNQCSCHF 775
            V PC  +C D  +  +C            CVEGC CPP   L DT+   C+P ++C C  
Sbjct: 2632 VPPCPPSCLDPKANRSCS---------GHCVEGCRCPPGLLLHDTR---CLPLSECPCLV 2679

Query: 776  -QGVDYPPGDSDIPSLGHCHCKDGVMSC 802
             + + +P     + +   C C+ G + C
Sbjct: 2680 GEELKWPGVSFLLGNCSQCVCEKGELLC 2707



 Score = 35.4 bits (80), Expect = 0.81
 Identities = 86/396 (21%), Positives = 118/396 (29%), Gaps = 71/396 (17%)

Query: 2229 TTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQ-QPCVALTVYVAMCHKFHVC 2287
            +T  +PC   +  R  S C    P ++ C      T+    QPC A      +      C
Sbjct: 2840 STCSAPCDGGIQTRGRS-CSSLAPGDTTCPGPHSQTRDCNTQPCTAQCPENMLFRSAEQC 2898

Query: 2288 IEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGIL------GPLDPEHCQVLGEGCVC 2341
             +      CP LC +      C   C P  TC  G+        P     CQ+ G+    
Sbjct: 2899 HQ--EGGPCPRLCLTQGPGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYAS 2956

Query: 2342 SEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNS-SLSGCCQHQCQA-------PD 2393
                 L   ++  C+   K ACT S   P A G  W+  +L   C   C           
Sbjct: 2957 GAMARLDSCNNCTCV-SGKMACT-SERCPVACG--WSPWTLWSLCSCSCNVGIRRRFRAG 3012

Query: 2394 TIVPVDLG---CPSPRPESCLRFGEVALLLPTKDPCC-LGTVCVCNQTLCEGLAPTCRPG 2449
            T  P   G   C  P  E+     E   L P   P    G    C        +  C  G
Sbjct: 3013 TAPPAAFGGAECQGPTMEA-----EFCSLRPCPGPGGEWGPWSPC--------SVPCGGG 3059

Query: 2450 HRLLTHFQEDSCCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCP 2509
            +R  T     S     +C   P  C   +   C +D+  +    G + C       G   
Sbjct: 3060 YRNRTRGSSRSLMEFSTCGLQP--CAGPVPGMCPRDKQWLDCAQGPASCAELSAPRGTNQ 3117

Query: 2510 DSIPECQEGEALTVHRNTTELCCPLYQCVC----------ENFRCPQVQCGLGTALV--- 2556
               P C     + +  N   +C P   C C               P   C   + L+   
Sbjct: 3118 TCHPGCHCPSGMLLLNN---VCVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANC 3174

Query: 2557 ---------EVWSPDRCCPYKSCECDCDTIPVPRCH 2583
                       WSP    P+  C   C      RCH
Sbjct: 3175 SSWPCAEGEPTWSP--WTPWSQCSASCGP---ARCH 3205



 Score = 34.7 bits (78), Expect = 1.4
 Identities = 31/104 (29%), Positives = 43/104 (41%), Gaps = 32/104 (30%)

Query: 2319 CQDGILGP-----LDPE-------HCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDS 2366
            CQ G++ P     LDP+       HC    EGC C  G +L   H   C+P ++C C   
Sbjct: 2627 CQKGLVPPCPPSCLDPKANRSCSGHCV---EGCRCPPGLLL---HDTRCLPLSECPC--- 2677

Query: 2367 MGVPRALGE--TW---NSSLSGCCQHQCQAPDTIVPVDLGCPSP 2405
                  +GE   W   +  L  C Q  C+  + +     GCP P
Sbjct: 2678 -----LVGEELKWPGVSFLLGNCSQCVCEKGELLCQPG-GCPLP 2715



 Score = 33.9 bits (76), Expect = 2.4
 Identities = 24/78 (30%), Positives = 33/78 (42%), Gaps = 7/78 (8%)

Query: 1338 WRYDACASPCFQTCRDPRAAS-CRDVPRVEGCVPVCPTPQVLDEVTQRCVYLEDCVEPAV 1396
            + + AC SPC   C    +   C+D+P    C P C  P+ L E    C+  E+C     
Sbjct: 4427 FEFHACGSPCAGLCATHLSHQLCQDLPP---CQPGCYCPKGLLEQAGGCIPPEEC---NC 4480

Query: 1397 WVPTEALGNETLPPSQGL 1414
            W  + A    TL P   L
Sbjct: 4481 WHTSAAGAGMTLAPGDRL 4498



 Score = 32.7 bits (73), Expect = 5.3
 Identities = 35/118 (29%), Positives = 47/118 (39%), Gaps = 26/118 (22%)

Query: 1727 MSLESTRPSQLL----SGLPPDTSLPLAKVGTSAPVAT----PGPKASV----------I 1768
            ++L S +P QLL     GL      P  +   ++P  T    PGP + V           
Sbjct: 2285 LALSSAQPGQLLHWPREGLAETEHWPPGQESPTSPTETRPVSPGPASGVPHHGESVQMVT 2344

Query: 1769 TTPL-QPQATTLPAQTLS-------PVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLG 1818
            TTP+ Q +A TLP    +       PV P TPA  + A  P        G  P  +LG
Sbjct: 2345 TTPIPQMEARTLPPGMAAVTVVPPHPVTPATPAGQSVAPGPFPPVQCGPGQTPCEVLG 2402



 Score = 32.7 bits (73), Expect = 5.3
 Identities = 26/88 (29%), Positives = 38/88 (43%), Gaps = 14/88 (15%)

Query: 2300 CSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHR-RHSALCIPE 2358
            C    +   C   C  P++CQD   G +    CQ    GC  + G  L +     LC+P 
Sbjct: 3529 CGGGQSLHPCGQPC--PRSCQDLSPGSV----CQPGSVGCQPTCGCPLGQLSQDGLCVPP 3582

Query: 2359 AKCAC---TDSMGVP----RALGETWNS 2379
            A C C     +MG+P    R+ G  ++S
Sbjct: 3583 AHCRCQYQPGAMGIPENQSRSAGSRFSS 3610


>gi|151301154 mucin 6, gastric [Homo sapiens]
          Length = 2439

 Score =  512 bits (1318), Expect = e-144
 Identities = 350/1152 (30%), Positives = 520/1152 (45%), Gaps = 87/1152 (7%)

Query: 79   CRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVS 138
            C  WG  H  TFD   Y  SG  +Y      +    +FS+Q+   P    S        S
Sbjct: 45   CSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRRGPDGSISRIIVELGAS 104

Query: 139  LFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQ---QLAGYVIVRHQSAFTLAWDGASA 195
            +  V E  I + K++   G+ + LP+     ++    Q    V  + +    + W   S 
Sbjct: 105  VVTVSEAIISV-KDI---GV-ISLPYTSNGLQITPFGQSVRLVAKQLELELEVVWGPDSH 159

Query: 196  VYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGP--T 253
            + + +  + +G   GLCGN +    ++ V+  GK  +      H +        PG   T
Sbjct: 160  LMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEP-----HKFAALQKLDDPGEICT 214

Query: 254  TSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSM--GD 311
               +P     Q     +      C  LL      C   VS  PF  SC +D+  +   G 
Sbjct: 215  FQDIPSTHVRQAQHARI------CTQLLTLVAPECS--VSKEPFVLSCQADVAAAPQPGP 266

Query: 312  VATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASC-HPRAS 370
              + C  L+EY+R C+  G+P++ WR+    C+V        Y EC + C  +C +P+ S
Sbjct: 267  QNSSCATLSEYSRQCSMVGQPVRRWRSP-GLCSVGQCPANQVYQECGSACVKTCSNPQHS 325

Query: 371  CVDSEIACVDGCYCPNGLIFEDGG----CVAPAECPCEFHGTLYPPGSVVKEDCNTCTCT 426
            C  S   C  GC+CP G +  D      CV   +CPC  HG +Y PG V    C TC CT
Sbjct: 326  CSSS---CTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTIAACQTCRCT 382

Query: 427  SGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRS---SGTFTVTLQNA 483
             G+W C+   CP  CS+ G    TTFD R Y F  TC YIL +S      G        +
Sbjct: 383  LGRWVCTERPCPGHCSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYDKS 442

Query: 484  PCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVF 543
              G++     + +V  +  QD   ++ ++Q   V    + K +P Y      + R +S  
Sbjct: 443  --GVSHSETSLVAVVYLSRQD---KIVISQDEVVTNNGEAKWLP-YKTRNITVFRQTSTH 496

Query: 544  LRVRTNVGVRVLYD-REGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQ 602
            L++ T+ G+ ++   R   + Y+ V  ++   T GLCG FNG+T DDF + +G+ E T  
Sbjct: 497  LQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTAS 556

Query: 603  LFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPY 660
            LF +SW+  +   P       DPC +       +   CS+L  TG +F  C A ++P P+
Sbjct: 557  LFVDSWRAGNC--PAALERETDPCSMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPF 614

Query: 661  FEQCRRDACRCGQ--PCLCATLAHYAHLCRRHGLPV-DFRARLPACALSCEASKEYSPCV 717
            +++C   AC   +  P +CA L  Y H C   G+ +  +R+ +  C + C  +  +S   
Sbjct: 615  YKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNS 674

Query: 718  APCGRTCQDLASPEACGVDGGDDLSRDEC------VEGCACPPDTYLDTQADLCVPRNQC 771
              C RTC  L+                EC      V+GC CP  TYL+ + + CV + QC
Sbjct: 675  QACERTCLSLSDRAT------------ECHHSAVPVDGCNCPDGTYLNQKGE-CVRKAQC 721

Query: 772  SCHFQGVDYPPGDSDIPSLG-HCHCKDGVMSCDSRAPA--AACPAGQVFVNCSDLHTD-L 827
             C  +G  +   +      G  CHC +G +SC  R     A+C A + F +CS    +  
Sbjct: 722  PCILEGYKFILAEQSTVINGITCHCINGRLSCPQRPQMFLASCQAPKTFKSCSQSSENKF 781

Query: 828  ELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDA-CFLPEECPCTWKGKEYFPGD 886
              +   TC Q L          C  GC C +GL  + D  C  PEECPC + G  Y  G 
Sbjct: 782  GAACAPTC-QMLATGVACVPTKCEPGCVCAEGLYENADGQCVPPEECPCEFSGVSYPGGA 840

Query: 887  QVMSPCHTCVCQRGSFQCTLHP-CASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD 945
            ++ + C TC C RG + C     C STCT YG+ H  TFDG  F F G C+  L      
Sbjct: 841  ELHTDCRTCSCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCG 900

Query: 946  VS-----FSVIVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHT 1000
            V+     F ++ ENV C +SG+ C + I I +G   +V  D +   + E     +  V  
Sbjct: 901  VNDSQPTFKILTENVICGNSGVTCSRAIKIFLGGLSVVLADRNYTVTGEE-PHVQLGVTP 959

Query: 1001 WRVGFFTLVHFPQEH-ITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENL 1059
              +     +  P  + +TL+W++  T+ ++     Q  L GLCGNF+    ++  T    
Sbjct: 960  GALSLVVDISIPGRYNLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRY 1019

Query: 1060 ELTNPQEFGSSWAAVE-CPDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVT 1118
              ++  E  +SW     C D     D C LN  R  +A+++CS++ S+ F  CH  V   
Sbjct: 1020 VASSELELVNSWKESPLCGDVSFVTDPCSLNAFRRSWAERKCSVINSQTFATCHSKVYHL 1079

Query: 1119 WFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVL- 1177
             +Y  C+ D CGC  GGDCEC C +V+AYA  C   GV VDWRTP  CP  C F+N    
Sbjct: 1080 PYYEACVRDACGCDSGGDCECLCDAVAAYAQACLDKGVCVDWRTPAFCPIYCGFYNTHTQ 1139

Query: 1178 -GKGPYQLSSLA 1188
             G G YQ +  A
Sbjct: 1140 DGHGEYQYTQEA 1151



 Score =  226 bits (577), Expect = 2e-58
 Identities = 218/864 (25%), Positives = 335/864 (38%), Gaps = 197/864 (22%)

Query: 79   CRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVS 138
            C   G   V TFD   Y   G  +Y L+   +       + V++  + G S    S    
Sbjct: 397  CSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYD--KSGVSHSETSLVAV 454

Query: 139  LFFVGEQEIHLAKE--VTHGGMRVQLPHV--------MGSARLQQLAGY---VIVRHQSA 185
            ++   + +I ++++  VT+ G    LP+           S  LQ    +   ++V+ +  
Sbjct: 455  VYLSRQDKIVISQDEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQLRPI 514

Query: 186  FTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQE-- 243
            F          Y+ + P+  G T GLCGN N D  DD  TS G        FV SW+   
Sbjct: 515  FQ--------AYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWRAGN 566

Query: 244  --QAPNQPPGPTTSSLPRPPCLQQNPGTMQG---VYEQCEALLRPP-------FDACHAY 291
               A  +   P + S     C + +   +     V+E+C A + P        + AC+ Y
Sbjct: 567  CPAALERETDPCSMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQACN-Y 625

Query: 292  VSPLPF-----------------------------TASCTSDL------------CQSMG 310
                P                              T  CT +             C S+ 
Sbjct: 626  EETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLSLS 685

Query: 311  DVATWCRALAEYARAC-----------------AQAGRPLQGWR-------TQLRQCTVH 346
            D AT C   A     C                 AQ    L+G++       T +   T H
Sbjct: 686  DRATECHHSAVPVDGCNCPDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVINGITCH 745

Query: 347  C---------KEKAF--------TYNECIACCP----ASCHPRASCVDSEIACVD----- 380
            C         + + F        T+  C         A+C P    + + +ACV      
Sbjct: 746  CINGRLSCPQRPQMFLASCQAPKTFKSCSQSSENKFGAACAPTCQMLATGVACVPTKCEP 805

Query: 381  GCYCPNGLIFE-DGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTAV-CP 438
            GC C  GL    DG CV P ECPCEF G  YP G+ +  DC TC+C+ G+W C     CP
Sbjct: 806  GCVCAEGLYENADGQCVPPEECPCEFSGVSYPGGAELHTDCRTCSCSRGRWACQQGTHCP 865

Query: 439  AECSVTGDIHFTTFDGRRYTFPATCQYILAK-----SRSSGTFTVTLQNAPCGLNQDGAC 493
            + C++ G+ H  TFDG+R+ F   C+YILA      + S  TF +  +N  CG N    C
Sbjct: 866  STCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPTFKILTENVICG-NSGVTC 924

Query: 494  VQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVR 553
             +++ + L       V L      +  ++  +    T  A  +     V + +     + 
Sbjct: 925  SRAIKIFLGG---LSVVLADRNYTVTGEEPHVQLGVTPGALSL----VVDISIPGRYNLT 977

Query: 554  VLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA 613
            ++++R  + + +++ +   +   GLCG FNGN +DDF +      S+     NSWK    
Sbjct: 978  LIWNRH-MTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSWKESPL 1036

Query: 614  CSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQ 673
            C  +      DPC ++    S++ + CSV+  + FA C + +  +PY+E C RDAC C  
Sbjct: 1037 CGDV--SFVTDPCSLNAFRRSWAERKCSVINSQTFATCHSKVYHLPYYEACVRDACGCDS 1094

Query: 674  ----PCLCATLAHYAHLCRRHGLPVDFRARLPA-CALSC--------------------E 708
                 CLC  +A YA  C   G+ VD+R   PA C + C                     
Sbjct: 1095 GGDCECLCDAVAAYAQACLDKGVCVDWRT--PAFCPIYCGFYNTHTQDGHGEYQYTQEAN 1152

Query: 709  ASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCA-CPPDTYLDTQADLCVP 767
             +  Y PC+ P        + P++  V G +       +EGC  C  D Y D +  +CVP
Sbjct: 1153 CTWHYQPCLCP--------SQPQS--VPGSN-------IEGCYNCSQDEYFDHEEGVCVP 1195

Query: 768  RNQCSCHFQGVDYPPGDSDIPSLG 791
                 C       PP    +P+ G
Sbjct: 1196 -----CMPPTTPQPPTTPQLPTTG 1214



 Score =  118 bits (295), Expect = 1e-25
 Identities = 114/402 (28%), Positives = 172/402 (42%), Gaps = 43/402 (10%)

Query: 434 TAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSG--TFTVTLQNAPCGLNQDG 491
           TA    +CS  G  HF+TFD   Y F  TC YI A +      TF+V L+  P G     
Sbjct: 38  TAPDKGQCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRRGPDG----- 92

Query: 492 ACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRL--SSVFLRVRTN 549
               S+S I+ +     VT+++A  + + D   I  PYT +  +I     S   +  +  
Sbjct: 93  ----SISRIIVELGASVVTVSEA-IISVKDIGVISLPYTSNGLQITPFGQSVRLVAKQLE 147

Query: 550 VGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWK 609
           + + V++  +   L + V+++++    GLCG F+G   ++F+S  G     P  F    K
Sbjct: 148 LELEVVWGPDS-HLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEG-KFLEPHKFAALQK 205

Query: 610 TLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDAC 669
                 P    +  D    H++ A ++ + C+ L   +   CS  +S  P+   C+ D  
Sbjct: 206 ---LDDPGEICTFQDIPSTHVRQAQHA-RICTQLLTLVAPECS--VSKEPFVLSCQADVA 259

Query: 670 RCGQP----CLCATLAHYAHLCRRHGLPVDFRARLPA-CAL-SCEASKEYSPCVAPCGRT 723
              QP      CATL+ Y+  C   G PV  R R P  C++  C A++ Y  C + C +T
Sbjct: 260 AAPQPGPQNSSCATLSEYSRQCSMVGQPVR-RWRSPGLCSVGQCPANQVYQECGSACVKT 318

Query: 724 CQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQAD--LCVPRNQCSCHFQGVDYP 781
           C +     +C            C  GC CP  T L+  ++   CVP  QC C   G  Y 
Sbjct: 319 CSN--PQHSCS---------SSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYA 367

Query: 782 PGDSDIPSLGHCHCKDGVMSCDSR-APAAACPAGQVFVNCSD 822
           PG+  I +   C C  G   C  R  P      G  FV   D
Sbjct: 368 PGEVTIAACQTCRCTLGRWVCTERPCPGHCSLEGGSFVTTFD 409



 Score =  111 bits (277), Expect = 1e-23
 Identities = 117/426 (27%), Positives = 164/426 (38%), Gaps = 67/426 (15%)

Query: 32   KCAPSYLFSCFNG------GECVHPAFCDCRRFNATGP---------------RCQMVYN 70
            KC P  +  C  G      G+CV P  C C     + P               R +    
Sbjct: 802  KCEPGCV--CAEGLYENADGQCVPPEECPCEFSGVSYPGGAELHTDCRTCSCSRGRWACQ 859

Query: 71   AGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLV----GRHEPEGQSFSIQVHNDPQC 126
             G    S C  +G+ HV TFDG  +   G   Y L     G ++ +  +F I   N   C
Sbjct: 860  QGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQ-PTFKILTEN-VIC 917

Query: 127  GSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAF 186
            G+S  TCSRA+ +F  G   +   +  T  G   + PHV        L+  V +     +
Sbjct: 918  GNSGVTCSRAIKIFLGGLSVVLADRNYTVTG---EEPHVQLGVTPGALSLVVDISIPGRY 974

Query: 187  --TLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQ 244
              TL W+    + I+++        GLCGN N + KDD  T S  +    +E V+SW+E 
Sbjct: 975  NLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSWKES 1034

Query: 245  APNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSD 304
                 P     S    PC   N         +C  +    F  CH+ V  LP+  +C  D
Sbjct: 1035 -----PLCGDVSFVTDPC-SLNAFRRSWAERKCSVINSQTFATCHSKVYHLPYYEACVRD 1088

Query: 305  L--CQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHC---------KEKAFT 353
               C S GD    C A+A YA+AC   G  +  WRT    C ++C             + 
Sbjct: 1089 ACGCDSGGDCECLCDAVAAYAQACLDKGVCVD-WRTP-AFCPIYCGFYNTHTQDGHGEYQ 1146

Query: 354  YNECIACC----PASCHPRASCVDSEIACVDGCY-CPNGLIF--EDGGCVAPAECPCEFH 406
            Y +   C     P  C  +   V    + ++GCY C     F  E+G CV     PC   
Sbjct: 1147 YTQEANCTWHYQPCLCPSQPQSVPG--SNIEGCYNCSQDEYFDHEEGVCV-----PCMPP 1199

Query: 407  GTLYPP 412
             T  PP
Sbjct: 1200 TTPQPP 1205



 Score = 94.4 bits (233), Expect = 1e-18
 Identities = 176/738 (23%), Positives = 253/738 (34%), Gaps = 116/738 (15%)

Query: 1336 CEWRYDACASPCFQTCRDPRAASCRDVP--RVEGCVPVCPTPQVLDEVTQRCVYLEDCVE 1393
            C W Y  C  P          +  + VP   +EGC   C   +  D     CV    C+ 
Sbjct: 1153 CTWHYQPCLCP----------SQPQSVPGSNIEGCYN-CSQDEYFDHEEGVCV---PCMP 1198

Query: 1394 PAVWVP--TEALGNETLPPSQ-----------GLPTPSDEEPQLSQESPRTPTHRP---- 1436
            P    P  T  L      P+Q           GL + +   P  S  +P +PT  P    
Sbjct: 1199 PTTPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPS-SNHTPASPTQTPLLPA 1257

Query: 1437 ALTPAAPLTTALNPP-VTATEEPVVSPG--PTQTTLQQPLELTASQLPAGPTESPASKGV 1493
             LT + P  ++  PP  T    P  + G  PT T      + T +Q     T S AS   
Sbjct: 1258 TLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATASTASPAT 1317

Query: 1494 TASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSR---SPPAP 1550
            T++  +   T  +   P    T      S   E    T      P  T +S    + P P
Sbjct: 1318 TSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGPTTPQP 1377

Query: 1551 RFPLMTKAVTVRGHGSLPVRTTPLQPSLTASP--SSRPVASPGAISRS--------PTSS 1600
              P    A       +    TTP  P  T SP  +  PV S G ++ +        PT S
Sbjct: 1378 GQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPTPS 1437

Query: 1601 GSH-----------KAVLTPAVTKVISRTGVPQPTQAQSASSPS------TPLTVAGTAA 1643
                           +++TP+   VI+ T     T A + S+P+      T L   G+  
Sbjct: 1438 HPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKATGSTH 1497

Query: 1644 EQVPVSPL--ATRSLEIVLSTEKGEAG-HS------QPMGSPASP---QPHPLPSAPPRP 1691
               P++P    T       ST K     HS       P  +P S     P+P  +    P
Sbjct: 1498 TAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTP 1557

Query: 1692 AQHTTMATRSPALPPET----PAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSL 1747
              HT  AT S   PP T    P  +S  ++T  + AT F +  +T P+       P T+L
Sbjct: 1558 VAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT-TTTYPTP----SHPQTTL 1612

Query: 1748 PLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHPPTHIAP- 1806
            P      S  + T  P    + TP   Q  T  +    P     P    +A   TH AP 
Sbjct: 1613 PTHVPPFSTSLVT--PSTHTVITPTHAQMATSASIHSMPTGTIPPPTTLKATGSTHTAPT 1670

Query: 1807 ---PAAGTAPGLLLGATLPTSGVLPV-------AEGTA-SMVSVVPRKSTTG--KVAILS 1853
                 +GT+  L    T  TS  L         AE T+ S  ++ P  ++TG   + + +
Sbjct: 1671 MTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTT 1730

Query: 1854 KQVSLPTSMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVP--TSYALSRVSAR 1911
               S   S + +A+      T  + H  T     PE     T    P  TS       A 
Sbjct: 1731 SGTSQSRSSFSTAK------TSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAH 1784

Query: 1912 TAPQDSMLVLLPQLAEAHGTSAGPHLAAEPVD----EATTEPSGRSAPALSIVEGLAEAL 1967
            T    S  +  P    +  T   P  +  PV     + TT     S P  ++   +    
Sbjct: 1785 TTSATSSRLPTPFTTHSPPTGTTPISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFS 1844

Query: 1968 ATTTEANTSTTCVPIAEQ 1985
             +    +T T  +P   Q
Sbjct: 1845 TSLVTPSTHTVIIPTHTQ 1862



 Score = 92.8 bits (229), Expect = 4e-18
 Identities = 128/530 (24%), Positives = 195/530 (36%), Gaps = 74/530 (13%)

Query: 1972 EANTSTTCVPIAEQDCVRHICLEGQ-LIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCC 2030
            + + + TCVP+ +  CV H  +     + +   Q C       RC +        G   C
Sbjct: 344  DLSNNHTCVPVTQCPCVLHGAMYAPGEVTIAACQTC-------RCTL--------GRWVC 388

Query: 2031 PLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSP---DEMLTVHVLDCKSANLGH 2087
                C   CS+       TFD           YIL QSP   ++   + V D   + + H
Sbjct: 389  TERPCPGHCSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYD--KSGVSH 446

Query: 2088 LNWPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRI--EDTGHMYMILT 2145
                   +V L+      ++ I + +  VT + +  W P       +  + + H+ M  +
Sbjct: 447  SETSLVAVVYLSRQD---KIVISQ-DEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATS 502

Query: 2146 PSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFL 2205
                 +  L       V      + Q  GLCG  +GD  +D T   G   G A   + F+
Sbjct: 503  FGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTA---SLFV 559

Query: 2206 DSWQV------------PSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRTFSACHRFVPP 2253
            DSW+             P S++ + +       CA T CS  LR  +   F  CH  V P
Sbjct: 560  DSWRAGNCPAALERETDPCSMSQLNKV------CAETHCSMLLR--TGTVFERCHATVNP 611

Query: 2254 ESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCI-EWRRS-DYCPFLCSSDSTYQ 2307
              F +  +      ++     C AL  YV  C    V +  WR S D C   C+ ++T+ 
Sbjct: 612  APFYKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFS 671

Query: 2308 ACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSM 2367
                ACE  +TC        +  H  V  +GC C +GT L+++    C+ +A+C C    
Sbjct: 672  YNSQACE--RTCLSLSDRATECHHSAVPVDGCNCPDGTYLNQKGE--CVRKAQCPCI-LE 726

Query: 2368 GVPRALGE---TWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRP-ESCLRFGE---VALLL 2420
            G    L E     N     C   +   P         C +P+  +SC +  E    A   
Sbjct: 727  GYKFILAEQSTVINGITCHCINGRLSCPQRPQMFLASCQAPKTFKSCSQSSENKFGAACA 786

Query: 2421 PTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCECD 2470
            PT      G  CV   T CE   P C     L  +  +  C P   C C+
Sbjct: 787  PTCQMLATGVACV--PTKCE---PGCVCAEGLYEN-ADGQCVPPEECPCE 830



 Score = 92.4 bits (228), Expect = 6e-18
 Identities = 146/606 (24%), Positives = 231/606 (38%), Gaps = 63/606 (10%)

Query: 1411 SQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTTLQ 1470
            SQ   + S  +   S  S  + TH P +TP +  T   NP  T T  PV     + T+ +
Sbjct: 1510 SQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTN-SATSSR 1568

Query: 1471 QPLELTASQLPAGPTESPASKGVTASLLAIPHT-PESSSLPVALQTPTPGMVSGAMETTR 1529
             P   T    P G +   ++  +TA+      T P  S     L T  P   +  +  + 
Sbjct: 1569 PPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPST 1628

Query: 1530 VTVIFAGSPNITVSS--RSPPAPRFPLMTKAVTVRGHGSLPVRTTPLQPSLTASPSSRPV 1587
             TVI      +  S+   S P    P  T   T++  GS    T P   +LT S +S+ +
Sbjct: 1629 HTVITPTHAQMATSASIHSMPTGTIPPPT---TLKATGS--THTAPTM-TLTTSGTSQAL 1682

Query: 1588 ASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV-PQPTQAQSASSPSTPLTVAGTAAEQV 1646
            +S    +++ TS  SH +    A     S T + P PT   S  +P   +T +GT+  + 
Sbjct: 1683 SSLNT-AKTSTSLHSHTSSTHHAEATSTSTTNITPNPT---STGTPPMTVTTSGTSQSR- 1737

Query: 1647 PVSPLATRSLEIVLSTEKGEAGHSQPMG-SPASPQPHPLPSAPPRPAQHTTMATRSPALP 1705
              S  +T      L +      H +    S  S  P+   +    P  HTT AT S    
Sbjct: 1738 --SSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPT 1795

Query: 1706 PET----PAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAPVATP 1761
            P T    P   +  ++T  + AT F +  +T P+       P T+LP      S  + TP
Sbjct: 1796 PFTTHSPPTGTTPISSTGPVTATSFQT-TTTYPTP----SHPHTTLPTHVPSFSTSLVTP 1850

Query: 1762 GPKASVITTPLQPQAT----TLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLL 1817
                 +I T  Q   +    ++P  T+ P  P T  A    H    + P  +GT+     
Sbjct: 1851 STHTVIIPTHTQMATSASIHSMPTGTIPP--PTTIKATGSTHTAPPMTPTTSGTSQSPSS 1908

Query: 1818 GATLPTSGVLPVAEGT--------ASMVSVVPRKSTTGKVAILSKQVS-----LPTSM-- 1862
             +T  TS  LP    +         S  ++ P+ ++TG    ++   S     LPT    
Sbjct: 1909 FSTAKTSTSLPYHTSSTHHPEVTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTT 1968

Query: 1863 ----YGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPV---PTSYALSRVSARTAPQ 1915
                 GS+    T    ATS   T     P   Q  T LP    P S +L   S  T   
Sbjct: 1969 HSPPTGSSPFSSTGPMTATSFQTTTTYPTPSHPQ--TTLPTHVPPFSTSLVTPSTHTV-- 2024

Query: 1916 DSMLVLLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSI-VEGLAEALATTTEAN 1974
              ++    Q+A +    + P     P        S  +AP +++   G ++  ++ + A 
Sbjct: 2025 --IITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPPMTVTTSGTSQTHSSFSTAT 2082

Query: 1975 TSTTCV 1980
             S++ +
Sbjct: 2083 ASSSFI 2088



 Score = 76.6 bits (187), Expect = 3e-13
 Identities = 68/270 (25%), Positives = 113/270 (41%), Gaps = 23/270 (8%)

Query: 908  PCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSSGMICRKF 967
            P    C+ +G  H+ TFD   +DF G C  ++  +T   +F      +     G I R  
Sbjct: 40   PDKGQCSTWGAGHFSTFDHHVYDFSGTCN-YIFAATCKDAFPTFSVQLRRGPDGSISRII 98

Query: 968  IS-----INVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQ 1022
            +      + V  ++I   D      P  +  +  ++  +      +    +  + ++W  
Sbjct: 99   VELGASVVTVSEAIISVKDIGVISLP--YTSNGLQITPFGQSVRLVAKQLELELEVVWGP 156

Query: 1023 RTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTLDP 1082
             + + V    ++ GQ+ GLCGNFD K  NE  + E  +   P +F    AA++  D  DP
Sbjct: 157  DSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEG-KFLEPHKF----AALQKLD--DP 209

Query: 1083 RDMCVLNPL-----REPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDC 1137
             ++C    +     R+    + C+ LL+ V   C   V    F  +C  D     Q G  
Sbjct: 210  GEICTFQDIPSTHVRQAQHARICTQLLTLVAPECS--VSKEPFVLSCQADVAAAPQPGPQ 267

Query: 1138 ECFCASVSAYAHQCCQHGVAV-DWRTPRLC 1166
               CA++S Y+ QC   G  V  WR+P LC
Sbjct: 268  NSSCATLSEYSRQCSMVGQPVRRWRSPGLC 297



 Score = 70.9 bits (172), Expect = 2e-11
 Identities = 122/521 (23%), Positives = 199/521 (38%), Gaps = 76/521 (14%)

Query: 1407 TLPPSQGLPTPSDEEPQLSQESPRTPT-----HRPALTPAAPLTTALNPPVTATEEPVVS 1461
            T+PP    PT            P TPT       P+    A  +T+L    ++T  P V+
Sbjct: 1876 TIPP----PTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVT 1931

Query: 1462 PGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMV 1521
            P  T T +      T ++ P   T S +S  +        H+P + S P +   P   M 
Sbjct: 1932 PTST-TNITPKHTSTGTRTPVAHTTSASSSRLPTPFTT--HSPPTGSSPFSSTGP---MT 1985

Query: 1522 SGAMETTRVTVIFAGSPNITVSSRSPPAPR-----------FPLMTKAVTVRGHGSLPVR 1570
            + + +TT  T      P  T+ +  PP                  T+  T     S P  
Sbjct: 1986 ATSFQTT-TTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTG 2044

Query: 1571 TTPLQPSLTASPSSRPVASPGAISRSPTS-SGSHKAVLTPAVTKVISRTGVPQPTQAQSA 1629
            T P   +L A+ S+   A P  ++ S TS + S  +  T + + + S + +PQ + ++  
Sbjct: 2045 TVPPPTTLKATGSTH-TAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPP 2103

Query: 1630 SSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPH-PLPSAP 1688
            SSP T          Q+P            LS+       +  + S  SP P  P   + 
Sbjct: 2104 SSPIT---------TQLP-----------HLSSATTPVSTTNQLSSSFSPSPSAPSTVSS 2143

Query: 1689 PRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLP 1748
              P+ H++  T SP          S+ T++  ++A    +  S+     LS  P   S+ 
Sbjct: 2144 YVPSSHSSPQTSSP----------SVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVS 2193

Query: 1749 LAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPA 1808
             + +  S+P A+   +A++  T   P        TLS +LP +   ++   P +H+A   
Sbjct: 2194 ASPLFPSSPAASTTIRATLPHTISSP-------FTLSALLPISTVTVSPT-PSSHLASST 2245

Query: 1809 AGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTS---MYGS 1865
                      A+  T+        T+   S+  R  T+G V++ S    +PTS      +
Sbjct: 2246 IAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNLTT 2305

Query: 1866 AEGGPTELTPATSHPLTPLVAE---PEGAQAGT-ALPVPTS 1902
               GPT L+P T    + L A    P  A   +   P PTS
Sbjct: 2306 RHPGPT-LSPTTRFLTSSLTAHGSTPASAPVSSLGTPTPTS 2345



 Score = 55.1 bits (131), Expect = 1e-06
 Identities = 70/288 (24%), Positives = 107/288 (37%), Gaps = 47/288 (16%)

Query: 2119 DLQPVWPPVSRYGFRIEDTGHMYMILTPS---DIQIQWLHSSGLMIVEASKTSKAQGHGL 2175
            D+  +  P +  G +I   G    ++      ++++ W   S LM++   K    Q  GL
Sbjct: 117  DIGVISLPYTSNGLQITPFGQSVRLVAKQLELELEVVWGPDSHLMVLVERKYM-GQMCGL 175

Query: 2176 CGICDGDAANDLTLKDG--------SVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSC 2227
            CG  DG   N+   ++G        + +   +DP        +PS  T V Q +      
Sbjct: 176  CGNFDGKVTNEFVSEEGKFLEPHKFAALQKLDDPGEICTFQDIPS--THVRQAQH----- 228

Query: 2228 ATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP------CVALTVYVAMC 2281
                C+  L +V      A    V  E F      D     QP      C  L+ Y   C
Sbjct: 229  -ARICTQLLTLV------APECSVSKEPFVLSCQADVAAAPQPGPQNSSCATLSEYSRQC 281

Query: 2282 HKFHVCI-EWRRSDYCPF-LCSSDSTYQACVTACEPPKTCQDGILGPLDPEH--CQVLGE 2337
                  +  WR    C    C ++  YQ C +AC   KTC        +P+H        
Sbjct: 282  SMVGQPVRRWRSPGLCSVGQCPANQVYQECGSAC--VKTCS-------NPQHSCSSSCTF 332

Query: 2338 GCVCSEGTILH-RRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGC 2384
            GC C EGT+L+   ++  C+P  +C C    G   A GE   ++   C
Sbjct: 333  GCFCPEGTVLNDLSNNHTCVPVTQCPCV-LHGAMYAPGEVTIAACQTC 379



 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 84/384 (21%), Positives = 129/384 (33%), Gaps = 92/384 (23%)

Query: 1975 TSTTCVPI-AEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLW 2033
            T   CVP   E  CV   C EG L      Q  P    P  C   G++   G +      
Sbjct: 794  TGVACVPTKCEPGCV---CAEG-LYENADGQCVPPEECP--CEFSGVSYPGGAELHTDCR 847

Query: 2034 ECACR---------------CSIFPDLSFVTFDGSHVALFKEAIYIL---------SQSP 2069
             C+C                C+++ +   +TFDG          YIL         SQ  
Sbjct: 848  TCSCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPT 907

Query: 2070 DEMLTVHVL------DCKSANLGHLNWPPFCLVMLNMT------HLAHQVTIDRFNRKVT 2117
             ++LT +V+       C  A    L      L   N T      H+   VT    +  V 
Sbjct: 908  FKILTENVICGNSGVTCSRAIKIFLGGLSVVLADRNYTVTGEEPHVQLGVTPGALSLVVD 967

Query: 2118 VDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCG 2177
            + +        RY   +    HM                   +++  ++ S+    GLCG
Sbjct: 968  ISIP------GRYNLTLIWNRHM------------------TILIRIARASQDPLCGLCG 1003

Query: 2178 ICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSC---------A 2228
              +G+  +D   +   V   A      ++SW+        G   F  D C         A
Sbjct: 1004 NFNGNMKDDFETRSRYV---ASSELELVNSWK---ESPLCGDVSFVTDPCSLNAFRRSWA 1057

Query: 2229 TTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP------CVALTVYVAMCH 2282
               CS    +++++TF+ CH  V    + E  +RD             C A+  Y   C 
Sbjct: 1058 ERKCS----VINSQTFATCHSKVYHLPYYEACVRDACGCDSGGDCECLCDAVAAYAQACL 1113

Query: 2283 KFHVCIEWRRSDYCPFLCSSDSTY 2306
               VC++WR   +CP  C   +T+
Sbjct: 1114 DKGVCVDWRTPAFCPIYCGFYNTH 1137



 Score = 49.3 bits (116), Expect = 5e-05
 Identities = 65/276 (23%), Positives = 111/276 (40%), Gaps = 37/276 (13%)

Query: 1392 VEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRP-----ALTPAAPLTT 1446
            +  + W+P  +    + PPS  + T   + P LS  +    T        + +P+AP T 
Sbjct: 2088 ISSSSWLPQNS---SSRPPSSPITT---QLPHLSSATTPVSTTNQLSSSFSPSPSAPSTV 2141

Query: 1447 ALNPPVTATEEPVVSP--GPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTP 1504
            +   P + +     SP  G + + +  P+  T   L +G   S ++   TAS+ A P  P
Sbjct: 2142 SSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTT--LSSGSHSSLSTHPTTASVSASPLFP 2199

Query: 1505 ESSSLPVALQTPTPGMVSGAMETTRV----TVIFAGSPNITVSSRS---PPAPRFPLMTK 1557
             S +    ++   P  +S     + +    TV  + +P+  ++S +   P  PR    T 
Sbjct: 2200 SSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTH 2259

Query: 1558 AVTVRGHGSLPVRTTPLQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISR 1617
                    S   R+T L    T  P+S  V+    ++  PTS           VT + +R
Sbjct: 2260 TAPAFSSQSTTSRSTSL---TTRVPTSGFVSLTSGVTGIPTS----------PVTNLTTR 2306

Query: 1618 TGVPQPTQAQSASSPSTPLTVAGTAAEQVPVSPLAT 1653
               P PT + +    ++ LT  G+     PVS L T
Sbjct: 2307 H--PGPTLSPTTRFLTSSLTAHGSTPASAPVSSLGT 2340



 Score = 33.9 bits (76), Expect = 2.4
 Identities = 18/66 (27%), Positives = 30/66 (45%), Gaps = 3/66 (4%)

Query: 2787 VNLVSCDGRCPSASIYNYNINTYARFCKCCREVGLQRRSVQLFC---ATNATWVPYTVQE 2843
            V +  C+G C SA+ +N         C CCR +    + ++L C   +T    +  T+Q 
Sbjct: 2367 VTVTRCEGACISAASFNIITQQVDARCSCCRPLHSYEQQLELPCPDPSTPGRRLVLTLQV 2426

Query: 2844 PTDCAC 2849
             + C C
Sbjct: 2427 FSHCVC 2432


>gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo
            sapiens]
          Length = 2134

 Score =  476 bits (1226), Expect = e-133
 Identities = 288/932 (30%), Positives = 447/932 (47%), Gaps = 65/932 (6%)

Query: 275  EQCEALLRPPFDACHAYVS-PLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGR-P 332
            + C  ++   F+ C    +    +   C  + CQ+    +T C   +E +R CA  G   
Sbjct: 687  QHCNKIIGTYFEKCGKVAALSNDYKMICIDEYCQTRDKTST-CDTYSELSRLCASDGPGT 745

Query: 333  LQGWRTQLRQC--TVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIF 390
             + WR+       T  C E+   Y EC    PA+C   A   DSE  CV GC CP G + 
Sbjct: 746  FESWRSDSDVVCETQRCPEQHI-YKECGPSNPATCSNVAPFQDSE--CVSGCTCPEGYLL 802

Query: 391  ED----GGCVAPAECPCEFHGTLYPPGSVVKEDCNT-CTCTSGKWECSTAVCPAECSVTG 445
            +D    G CV  AECPCE  GT+Y PG V +  C + CTC   KW C+ A+CP  C V G
Sbjct: 803  DDIGEKGKCVLKAECPCESSGTVYQPGEVREGPCGSQCTCQDAKWSCTEALCPGRCKVEG 862

Query: 446  DIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDP 505
                TTFDG +Y FP  C ++   +     ++++++  PC   Q G C+ SV+++L+   
Sbjct: 863  S-SLTTFDGVKYNFPGNCHFLAVHNED---WSISVELRPCPSGQTGTCLNSVTLLLNSSV 918

Query: 506  RRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRV-LYDREGLRLY 564
                 +  +   +  D+ +    Y  D  +I   SS +L+V T   V++ +     ++LY
Sbjct: 919  PVDKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASSSYLQVETYFHVKLQIQIVPVMQLY 978

Query: 565  LQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLD 624
            + +      DTVGLCG++N   +DDF+S   + E T Q F NSW+ +S       G+P  
Sbjct: 979  VSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMSC----PKGNP-S 1033

Query: 625  PCDVHLQAASYSVQACSVLTGEM--FAPCSAFLSPVPYFEQCRRDACRC--GQPCLCATL 680
             C + ++   ++ + C +L       A C   ++P PY E+C++  C C   Q CLC  L
Sbjct: 1034 SC-ISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTIL 1092

Query: 681  AHYAHLC-RRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPE-ACGVDGG 738
             +Y   C  +    V +R  L  C  SC +   +   V  C  +C+ L+  + +C V+  
Sbjct: 1093 GNYVKACAEKETYIVGWRTGL--CEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVE-- 1148

Query: 739  DDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCHCKDG 798
                 D  V+GC CP   Y + + + CV ++QC C+       PG         C C+DG
Sbjct: 1149 -----DVPVDGCTCPDAMYQNNEGN-CVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDG 1202

Query: 799  VMSCDSRAPAAA--CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARG-PCLSGCA 855
            ++ C          C  G  +V+CSD     +    RTC  +  N+ V     PC  GC 
Sbjct: 1203 ILLCQIPIDLTLQNCSGGAEYVDCSD--PKAQRRTNRTCSTR--NIPVFDENLPCKRGCF 1258

Query: 856  CPQGLLRHGDA-CFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCT 914
            CP+G++R+    C  P +CPC++ G+EY  G      C+ C C +GS+ CT + C + C 
Sbjct: 1259 CPEGMVRNSKGICVFPNDCPCSFGGREYDEGSVTSVGCNECTCIKGSWSCTQNECQTICH 1318

Query: 915  AYGDRHYRTFDGLPFDFVGACKVHLVKST---SDVSFSVIVENVNCYSSGMICRKFISIN 971
             YG+ H RTFDG  + F G C+   ++      + +F ++ E+V C   G+ C + I + 
Sbjct: 1319 IYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHENGTFRILTESVPCCEDGLTCSRKIIVA 1378

Query: 972  VGNSLIVFDDDSGNPSPESFLDDKQ--------EVHTWRVGFFTLVHFPQEHITLLWDQR 1023
              +  IV  D  G  +     + K+         +HT  VG + ++ F Q  I ++WD+ 
Sbjct: 1379 FQDQNIVLQD--GKVTAVKSTESKKCELNANAYSIHT--VGLYLILKF-QNGIIVIWDKN 1433

Query: 1024 TTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSW-AAVECPDTLDP 1082
            T + V   P W G++ GLCGN +    ++  T  +   +   EFG+SW  + EC DT+  
Sbjct: 1434 TRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQ 1493

Query: 1083 RDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCA 1142
               C  NP  + +A ++C IL    F  CH  VD + ++  C+ + C C   G    FC 
Sbjct: 1494 TFPCDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCT 1553

Query: 1143 SVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFN 1174
            +V+ YA  C   GV V WR P LCP  CD++N
Sbjct: 1554 AVAMYAEACSAVGVCVSWRKPNLCPVYCDYYN 1585



 Score =  211 bits (537), Expect = 8e-54
 Identities = 140/455 (30%), Positives = 201/455 (44%), Gaps = 41/455 (9%)

Query: 373  DSEIACVDGCYCPNGLIFEDGG-CVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWE 431
            D  + C  GC+CP G++    G CV P +CPC F G  Y  GSV    CN CTC  G W 
Sbjct: 1248 DENLPCKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYDEGSVTSVGCNECTCIKGSWS 1307

Query: 432  CSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKS---RSSGTFTVTLQNAPCGLN 488
            C+   C   C + G+ H  TFDG+ Y+F   CQY   +      +GTF +  ++ PC   
Sbjct: 1308 CTQNECQTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHENGTFRILTESVPCC-- 1365

Query: 489  QDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIP-PYTDDAFEIRRLSSVFLRVR 547
            +DG       ++  QD   Q  + Q G V      +        +A+ I  +  ++L ++
Sbjct: 1366 EDGLTCSRKIIVAFQD---QNIVLQDGKVTAVKSTESKKCELNANAYSIHTVG-LYLILK 1421

Query: 548  TNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNS 607
               G+ V++D+   RL + +D  W     GLCG  NG+ +DDF +      S    FGNS
Sbjct: 1422 FQNGIIVIWDKN-TRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNS 1480

Query: 608  WKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRD 667
            WKT   CS  V+ +   PCD +    +++V+ C +L    F  C   + P  Y + C  +
Sbjct: 1481 WKTSQECSDTVAQT--FPCDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEE 1538

Query: 668  ACRCGQPC----LCATLAHYAHLCRRHGLPVDFRARLPACALSC-------EASKEYSPC 716
            AC C         C  +A YA  C   G+ V +R +   C + C       E    Y PC
Sbjct: 1539 ACACDMEGKYLGFCTAVAMYAEACSAVGVCVSWR-KPNLCPVYCDYYNAPGECRWHYEPC 1597

Query: 717  VAPCGRTCQDLASPEACGVDGGDDLSRDECVEGC--ACPPDT-YLDTQADLCVPRNQCSC 773
                 +TC+D           G   S    +EGC   CP    YLD     CV  ++CSC
Sbjct: 1598 GTVTAKTCKDQLV--------GQKFS--SLLEGCYAKCPDSAPYLDENTMKCVSLSECSC 1647

Query: 774  HFQGVDYPPGDSDIPSLGH-CHCKDGVMSCDSRAP 807
             +  V  P G     + G  C+C  G + C   AP
Sbjct: 1648 FYNDV-IPAGGVIEDNCGRTCYCIAGQLECSETAP 1681



 Score =  132 bits (333), Expect = 4e-30
 Identities = 107/380 (28%), Positives = 167/380 (43%), Gaps = 34/380 (8%)

Query: 74   ERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRH-EPEGQSFSIQVHNDPQCGSSPYT 132
            E  +IC  +G+ HV TFDG  Y   G   Y+ +  +   E  +F I   + P C     T
Sbjct: 1312 ECQTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHENGTFRILTESVPCCEDG-LT 1370

Query: 133  CSRAVSLFFVGEQEIHLAKEVTH----GGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTL 188
            CSR + + F  +  +    +VT        + +L     +  +  +  Y+I++ Q+   +
Sbjct: 1371 CSRKIIVAFQDQNIVLQDGKVTAVKSTESKKCELN--ANAYSIHTVGLYLILKFQNGIIV 1428

Query: 189  AWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQ 248
             WD  + + + + P   G   GLCGNNN D KDD  T    +    +EF +SW+    +Q
Sbjct: 1429 IWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWK---TSQ 1485

Query: 249  PPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSD--LC 306
                T +     PC   NP        +CE L    F  CH  V P  +   C  +   C
Sbjct: 1486 ECSDTVAQ--TFPC-DSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACAC 1542

Query: 307  QSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCK------EKAFTYNECIAC 360
               G    +C A+A YA AC+  G     WR +   C V+C       E  + Y  C   
Sbjct: 1543 DMEGKYLGFCTAVAMYAEACSAVG-VCVSWR-KPNLCPVYCDYYNAPGECRWHYEPCGTV 1600

Query: 361  CPASCHPRASCVDSEI-ACVDGCY--CPNGLIFEDGG---CVAPAECPCEFHGTLYPPGS 414
               +C  +   V  +  + ++GCY  CP+   + D     CV+ +EC C F+  + P G 
Sbjct: 1601 TAKTC--KDQLVGQKFSSLLEGCYAKCPDSAPYLDENTMKCVSLSECSC-FYNDVIPAGG 1657

Query: 415  VVKEDC-NTCTCTSGKWECS 433
            V++++C  TC C +G+ ECS
Sbjct: 1658 VIEDNCGRTCYCIAGQLECS 1677



 Score =  111 bits (277), Expect = 1e-23
 Identities = 114/451 (25%), Positives = 164/451 (36%), Gaps = 83/451 (18%)

Query: 33   CAPSYLFSCFNG-GECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRA--------W- 82
            C   YL       G+CV  A C C            VY  G  R+  C +        W 
Sbjct: 796  CPEGYLLDDIGEKGKCVLKAECPCESSGT-------VYQPGEVREGPCGSQCTCQDAKWS 848

Query: 83   -------GQHHVE-----TFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSP 130
                   G+  VE     TFDG+ Y   G   +  V       + +SI V   P      
Sbjct: 849  CTEALCPGRCKVEGSSLTTFDGVKYNFPGNCHFLAV-----HNEDWSISVELRPCPSGQT 903

Query: 131  YTCSRAVSLFF-----VGEQEIHLAKEVTHGGMRVQ-------LPHVMGSARLQQLAGYV 178
             TC  +V+L       V +   +    VT+  +R Q       +     S+   Q+  Y 
Sbjct: 904  GTCLNSVTLLLNSSVPVDKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASSSYLQVETYF 963

Query: 179  IVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFV 238
             V+ Q            +Y+ M P     T GLCG+ N   +DD ++S   L      F 
Sbjct: 964  HVKLQIQIVPVMQ----LYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFA 1019

Query: 239  HSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQ------CEALL--RPPFDACHA 290
            +SW+  +                C + NP +   + ++      C  LL    P  +CH 
Sbjct: 1020 NSWEMMS----------------CPKGNPSSCISIEKEKFAERHCGILLDSSGPLASCHP 1063

Query: 291  YVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKE- 349
             V+P P+   C    C         C  L  Y +ACA+    + GWRT L  C   C   
Sbjct: 1064 IVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGL--CEHSCPSG 1121

Query: 350  KAFTYNECIACCPASCH---PRASCVDSEIACVDGCYCPNGLI-FEDGGCVAPAECPCEF 405
              F YN  +  C +SC     R    D E   VDGC CP+ +    +G CV  ++C C  
Sbjct: 1122 LVFKYN--VKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYI 1179

Query: 406  HGTLYPPGSVVKEDCNTCTCTSGKWECSTAV 436
            +  +  PG ++  D N C C  G   C   +
Sbjct: 1180 NDEVMQPGKLIHIDDNKCVCRDGILLCQIPI 1210



 Score = 75.5 bits (184), Expect = 7e-13
 Identities = 56/207 (27%), Positives = 89/207 (42%), Gaps = 26/207 (12%)

Query: 2174 GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDS---CATT 2230
            GLCG  +GD  +D T +  SV  GA +   F +SW+     +      F  DS   C   
Sbjct: 1450 GLCGNNNGDLKDDFTTRYSSVASGALE---FGNSWKTSQECSDTVAQTFPCDSNPYCKAW 1506

Query: 2231 DCSPCLRMVSNRTFSACHRFVPPESFCELWIRDT-------KYVQQPCVALTVYVAMCHK 2283
                C  ++ + TF  CH  V P ++ ++ I +        KY+   C A+ +Y   C  
Sbjct: 1507 AVRKC-EILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGF-CTAVAMYAEACSA 1564

Query: 2284 FHVCIEWRRSDYCPFLCSSDSTYQACVTACEP-----PKTCQDGILGPLDPEHCQVLGEG 2338
              VC+ WR+ + CP  C   +    C    EP      KTC+D ++G    +    L EG
Sbjct: 1565 VGVCVSWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVG----QKFSSLLEG 1620

Query: 2339 CV--CSEGTILHRRHSALCIPEAKCAC 2363
            C   C +       ++  C+  ++C+C
Sbjct: 1621 CYAKCPDSAPYLDENTMKCVSLSECSC 1647



 Score = 73.6 bits (179), Expect = 3e-12
 Identities = 124/529 (23%), Positives = 189/529 (35%), Gaps = 80/529 (15%)

Query: 1336 CEWRYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCP-TPQVLDEVTQRCVYLEDC--- 1391
            C W Y+ C +   +TC+D +    +    +EGC   CP +   LDE T +CV L +C   
Sbjct: 1590 CRWHYEPCGTVTAKTCKD-QLVGQKFSSLLEGCYAKCPDSAPYLDENTMKCVSLSECSCF 1648

Query: 1392 ---VEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTAL 1448
               V PA  V  +  G  T     G    S+  P  S  +  T T    L+  A +T   
Sbjct: 1649 YNDVIPAGGVIEDNCG-RTCYCIAGQLECSETAPTNSTFAVSTTTATTILSTGAAITLVT 1707

Query: 1449 NPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSS 1508
              P TA   P ++   ++TT              GP   P + G+T + + I  T  ++ 
Sbjct: 1708 GGPSTAASIPAITTSSSETT----------GTTLGPLTEPFTTGITETSVPIISTSGNAG 1757

Query: 1509 LPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLP 1568
            +   +     G    A  T  V     G+ +   S R+   PR    T AV   G GS P
Sbjct: 1758 MTGVVSPTVTGASGMAGTTGGVDAATTGAASENTSERA-GTPRVSGATPAV---GGGSTP 1813

Query: 1569 VRTTPLQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQS 1628
                P      A+ S     S G+I+ SP +S         A +   S++G   P+    
Sbjct: 1814 GEAGP-----GATVSGSTGVSAGSITASPGAS---------ATSSESSKSGTTGPSVGGK 1859

Query: 1629 ASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAP 1688
              + S+  T +   +     S  +T   +  ++ +    G      SP      P P +P
Sbjct: 1860 TGATSSEATSSEGMSGVTGQSLGSTAGSDSEITAKTSFTG-----SSPPGKLTRPSPGSP 1914

Query: 1689 PRPAQHTT------------------MATRSPALPPETPAAASLSTATDG---------- 1720
               +  TT                  + +   ++   T A +  +  T G          
Sbjct: 1915 GHFSGGTTEWGNVATTGAAGENTSGALGSTEGSVEATTSAGSGNTAGTSGTGDTGPGNTA 1974

Query: 1721 LAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAPVA----TPGPKASVITTPLQPQA 1776
            ++ TP +S  +T P    S  P +  +     G S        T    A +  TP    A
Sbjct: 1975 VSGTPVVSPGAT-PGAPGSSTPGEADIGNTSFGKSGKSGHDSLTVLNPAFLRRTPTVSAA 2033

Query: 1777 TTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSG 1825
            +T    T SPV   T AA   A   +   P   GT  G   G  + TSG
Sbjct: 2034 ST----TSSPVSKHTDAASATAVTISGSKPGTPGTPGGATSGGKI-TSG 2077



 Score = 49.7 bits (117), Expect = 4e-05
 Identities = 91/424 (21%), Positives = 152/424 (35%), Gaps = 59/424 (13%)

Query: 1975 TSTTCVPIAEQDCVRHI-CLEGQLIR-VNQSQHCPQGAAPPRCGILGLAVRVG------- 2025
            T +   P  + +CV    C EG L+  + +   C   A  P C   G   + G       
Sbjct: 778  TCSNVAPFQDSECVSGCTCPEGYLLDDIGEKGKCVLKAECP-CESSGTVYQPGEVREGPC 836

Query: 2026 GDRC--------CPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHV 2077
            G +C        C    C  RC +    S  TFDG          ++   + D  ++V +
Sbjct: 837  GSQCTCQDAKWSCTEALCPGRCKV-EGSSLTTFDGVKYNFPGNCHFLAVHNEDWSISVEL 895

Query: 2078 LDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDR--FNRKVTVDLQPVWPPVSRYGFRIE 2135
              C S   G       CL  + +  L   V +D+  FN   TV    +      Y  +I+
Sbjct: 896  RPCPSGQTGT------CLNSVTLL-LNSSVPVDKYVFNSDGTVTNDKIRNQGYYYSDKIQ 948

Query: 2136 --DTGHMYMILTPS---DIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLK 2190
              +    Y+ +       +QIQ +    L  V           GLCG  +  A +D    
Sbjct: 949  IFNASSSYLQVETYFHVKLQIQIVPVMQLY-VSMPPNQFTDTVGLCGSYNNKAEDDFMSS 1007

Query: 2191 DGSVVGGAEDPAPFLDSWQV-------PSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRT 2243
               +   ++    F +SW++       PSS  S+ + +F    C        + + S+  
Sbjct: 1008 QNILEKTSQ---AFANSWEMMSCPKGNPSSCISIEKEKFAERHCG-------ILLDSSGP 1057

Query: 2244 FSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCIEWRRSDYCPFL 2299
             ++CH  V P+ + E   + T   +      C  L  YV  C +    I   R+  C   
Sbjct: 1058 LASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHS 1117

Query: 2300 CSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEA 2359
            C S   ++  V AC              D E   V  +GC C +   +++ +   C+ ++
Sbjct: 1118 CPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPV--DGCTCPDA--MYQNNEGNCVLKS 1173

Query: 2360 KCAC 2363
            +C C
Sbjct: 1174 QCDC 1177


>gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo
            sapiens]
          Length = 2134

 Score =  476 bits (1226), Expect = e-133
 Identities = 288/932 (30%), Positives = 447/932 (47%), Gaps = 65/932 (6%)

Query: 275  EQCEALLRPPFDACHAYVS-PLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGR-P 332
            + C  ++   F+ C    +    +   C  + CQ+    +T C   +E +R CA  G   
Sbjct: 687  QHCNKIIGTYFEKCGKVAALSNDYKMICIDEYCQTRDKTST-CDTYSELSRLCASDGPGT 745

Query: 333  LQGWRTQLRQC--TVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIF 390
             + WR+       T  C E+   Y EC    PA+C   A   DSE  CV GC CP G + 
Sbjct: 746  FESWRSDSDVVCGTQRCPEQHI-YKECGPSNPATCSNVAPFQDSE--CVSGCTCPEGYLL 802

Query: 391  ED----GGCVAPAECPCEFHGTLYPPGSVVKEDCNT-CTCTSGKWECSTAVCPAECSVTG 445
            +D    G CV  AECPCE  GT+Y PG V +  C + CTC   KW C+ A+CP  C V G
Sbjct: 803  DDIGEKGKCVLKAECPCESSGTVYQPGEVREGPCGSQCTCQDAKWSCTEALCPGRCKVEG 862

Query: 446  DIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDP 505
                TTFDG +Y FP  C ++   +     ++++++  PC   Q G C+ SV+++L+   
Sbjct: 863  S-SLTTFDGVKYNFPGNCHFLAVHNED---WSISVELRPCPSGQTGTCLNSVTLLLNSSV 918

Query: 506  RRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRV-LYDREGLRLY 564
                 +  +   +  D+ +    Y  D  +I   SS +L+V T   V++ +     ++LY
Sbjct: 919  PVDKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASSSYLQVETYFHVKLQIQIVPVMQLY 978

Query: 565  LQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLD 624
            + +      DTVGLCG++N   +DDF+S   + E T Q F NSW+ +S       G+P  
Sbjct: 979  VSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMSC----PKGNP-S 1033

Query: 625  PCDVHLQAASYSVQACSVLTGEM--FAPCSAFLSPVPYFEQCRRDACRC--GQPCLCATL 680
             C + ++   ++ + C +L       A C   ++P PY E+C++  C C   Q CLC  L
Sbjct: 1034 SC-ISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTIL 1092

Query: 681  AHYAHLC-RRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPE-ACGVDGG 738
             +Y   C  +    V +R  L  C  SC +   +   V  C  +C+ L+  + +C V+  
Sbjct: 1093 GNYVKACAEKETYIVGWRTGL--CEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVE-- 1148

Query: 739  DDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCHCKDG 798
                 D  V+GC CP   Y + + + CV ++QC C+       PG         C C+DG
Sbjct: 1149 -----DVPVDGCTCPDAMYQNNEGN-CVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDG 1202

Query: 799  VMSCDSRAPAAA--CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARG-PCLSGCA 855
            ++ C          C  G  +V+CSD     +    RTC  +  N+ V     PC  GC 
Sbjct: 1203 ILLCQIPIDLTLQNCSGGAEYVDCSD--PKAQRRTNRTCSTR--NIPVFDENLPCKRGCF 1258

Query: 856  CPQGLLRHGDA-CFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCT 914
            CP+G++R+    C  P +CPC++ G+EY  G      C+ C C +GS+ CT + C + C 
Sbjct: 1259 CPEGMVRNSKGICVFPNDCPCSFGGREYDEGSVTSVGCNECTCIKGSWSCTQNECQTICH 1318

Query: 915  AYGDRHYRTFDGLPFDFVGACKVHLVKST---SDVSFSVIVENVNCYSSGMICRKFISIN 971
             YG+ H RTFDG  + F G C+   ++      + +F ++ E+V C   G+ C + I + 
Sbjct: 1319 IYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHENGTFRILTESVPCCEDGLTCSRKIIVA 1378

Query: 972  VGNSLIVFDDDSGNPSPESFLDDKQ--------EVHTWRVGFFTLVHFPQEHITLLWDQR 1023
              +  IV  D  G  +     + K+         +HT  VG + ++ F Q  I ++WD+ 
Sbjct: 1379 FQDQNIVLQD--GKVTAVKSTESKKCELNANAYSIHT--VGLYLILKF-QNGIIVIWDKN 1433

Query: 1024 TTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSW-AAVECPDTLDP 1082
            T + V   P W G++ GLCGN +    ++  T  +   +   EFG+SW  + EC DT+  
Sbjct: 1434 TRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQ 1493

Query: 1083 RDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCA 1142
               C  NP  + +A ++C IL    F  CH  VD + ++  C+ + C C   G    FC 
Sbjct: 1494 TFPCDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCT 1553

Query: 1143 SVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFN 1174
            +V+ YA  C   GV V WR P LCP  CD++N
Sbjct: 1554 AVAMYAEACSAVGVCVSWRKPNLCPVYCDYYN 1585



 Score =  211 bits (537), Expect = 8e-54
 Identities = 140/455 (30%), Positives = 201/455 (44%), Gaps = 41/455 (9%)

Query: 373  DSEIACVDGCYCPNGLIFEDGG-CVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWE 431
            D  + C  GC+CP G++    G CV P +CPC F G  Y  GSV    CN CTC  G W 
Sbjct: 1248 DENLPCKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYDEGSVTSVGCNECTCIKGSWS 1307

Query: 432  CSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKS---RSSGTFTVTLQNAPCGLN 488
            C+   C   C + G+ H  TFDG+ Y+F   CQY   +      +GTF +  ++ PC   
Sbjct: 1308 CTQNECQTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHENGTFRILTESVPCC-- 1365

Query: 489  QDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIP-PYTDDAFEIRRLSSVFLRVR 547
            +DG       ++  QD   Q  + Q G V      +        +A+ I  +  ++L ++
Sbjct: 1366 EDGLTCSRKIIVAFQD---QNIVLQDGKVTAVKSTESKKCELNANAYSIHTVG-LYLILK 1421

Query: 548  TNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNS 607
               G+ V++D+   RL + +D  W     GLCG  NG+ +DDF +      S    FGNS
Sbjct: 1422 FQNGIIVIWDKN-TRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNS 1480

Query: 608  WKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRD 667
            WKT   CS  V+ +   PCD +    +++V+ C +L    F  C   + P  Y + C  +
Sbjct: 1481 WKTSQECSDTVAQT--FPCDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEE 1538

Query: 668  ACRCGQPC----LCATLAHYAHLCRRHGLPVDFRARLPACALSC-------EASKEYSPC 716
            AC C         C  +A YA  C   G+ V +R +   C + C       E    Y PC
Sbjct: 1539 ACACDMEGKYLGFCTAVAMYAEACSAVGVCVSWR-KPNLCPVYCDYYNAPGECRWHYEPC 1597

Query: 717  VAPCGRTCQDLASPEACGVDGGDDLSRDECVEGC--ACPPDT-YLDTQADLCVPRNQCSC 773
                 +TC+D           G   S    +EGC   CP    YLD     CV  ++CSC
Sbjct: 1598 GTVTAKTCKDQLV--------GQKFS--SLLEGCYAKCPDSAPYLDENTMKCVSLSECSC 1647

Query: 774  HFQGVDYPPGDSDIPSLGH-CHCKDGVMSCDSRAP 807
             +  V  P G     + G  C+C  G + C   AP
Sbjct: 1648 FYNDV-IPAGGVIEDNCGRTCYCIAGQLECSETAP 1681



 Score =  132 bits (333), Expect = 4e-30
 Identities = 107/380 (28%), Positives = 167/380 (43%), Gaps = 34/380 (8%)

Query: 74   ERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRH-EPEGQSFSIQVHNDPQCGSSPYT 132
            E  +IC  +G+ HV TFDG  Y   G   Y+ +  +   E  +F I   + P C     T
Sbjct: 1312 ECQTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHENGTFRILTESVPCCEDG-LT 1370

Query: 133  CSRAVSLFFVGEQEIHLAKEVTH----GGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTL 188
            CSR + + F  +  +    +VT        + +L     +  +  +  Y+I++ Q+   +
Sbjct: 1371 CSRKIIVAFQDQNIVLQDGKVTAVKSTESKKCELN--ANAYSIHTVGLYLILKFQNGIIV 1428

Query: 189  AWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQ 248
             WD  + + + + P   G   GLCGNNN D KDD  T    +    +EF +SW+    +Q
Sbjct: 1429 IWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWK---TSQ 1485

Query: 249  PPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSD--LC 306
                T +     PC   NP        +CE L    F  CH  V P  +   C  +   C
Sbjct: 1486 ECSDTVAQ--TFPC-DSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACAC 1542

Query: 307  QSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCK------EKAFTYNECIAC 360
               G    +C A+A YA AC+  G     WR +   C V+C       E  + Y  C   
Sbjct: 1543 DMEGKYLGFCTAVAMYAEACSAVG-VCVSWR-KPNLCPVYCDYYNAPGECRWHYEPCGTV 1600

Query: 361  CPASCHPRASCVDSEI-ACVDGCY--CPNGLIFEDGG---CVAPAECPCEFHGTLYPPGS 414
               +C  +   V  +  + ++GCY  CP+   + D     CV+ +EC C F+  + P G 
Sbjct: 1601 TAKTC--KDQLVGQKFSSLLEGCYAKCPDSAPYLDENTMKCVSLSECSC-FYNDVIPAGG 1657

Query: 415  VVKEDC-NTCTCTSGKWECS 433
            V++++C  TC C +G+ ECS
Sbjct: 1658 VIEDNCGRTCYCIAGQLECS 1677



 Score =  111 bits (277), Expect = 1e-23
 Identities = 114/451 (25%), Positives = 164/451 (36%), Gaps = 83/451 (18%)

Query: 33   CAPSYLFSCFNG-GECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRA--------W- 82
            C   YL       G+CV  A C C            VY  G  R+  C +        W 
Sbjct: 796  CPEGYLLDDIGEKGKCVLKAECPCESSGT-------VYQPGEVREGPCGSQCTCQDAKWS 848

Query: 83   -------GQHHVE-----TFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSP 130
                   G+  VE     TFDG+ Y   G   +  V       + +SI V   P      
Sbjct: 849  CTEALCPGRCKVEGSSLTTFDGVKYNFPGNCHFLAV-----HNEDWSISVELRPCPSGQT 903

Query: 131  YTCSRAVSLFF-----VGEQEIHLAKEVTHGGMRVQ-------LPHVMGSARLQQLAGYV 178
             TC  +V+L       V +   +    VT+  +R Q       +     S+   Q+  Y 
Sbjct: 904  GTCLNSVTLLLNSSVPVDKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASSSYLQVETYF 963

Query: 179  IVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFV 238
             V+ Q            +Y+ M P     T GLCG+ N   +DD ++S   L      F 
Sbjct: 964  HVKLQIQIVPVMQ----LYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFA 1019

Query: 239  HSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQ------CEALL--RPPFDACHA 290
            +SW+  +                C + NP +   + ++      C  LL    P  +CH 
Sbjct: 1020 NSWEMMS----------------CPKGNPSSCISIEKEKFAERHCGILLDSSGPLASCHP 1063

Query: 291  YVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKE- 349
             V+P P+   C    C         C  L  Y +ACA+    + GWRT L  C   C   
Sbjct: 1064 IVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGL--CEHSCPSG 1121

Query: 350  KAFTYNECIACCPASCH---PRASCVDSEIACVDGCYCPNGLI-FEDGGCVAPAECPCEF 405
              F YN  +  C +SC     R    D E   VDGC CP+ +    +G CV  ++C C  
Sbjct: 1122 LVFKYN--VKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYI 1179

Query: 406  HGTLYPPGSVVKEDCNTCTCTSGKWECSTAV 436
            +  +  PG ++  D N C C  G   C   +
Sbjct: 1180 NDEVMQPGKLIHIDDNKCVCRDGILLCQIPI 1210



 Score = 75.5 bits (184), Expect = 7e-13
 Identities = 56/207 (27%), Positives = 89/207 (42%), Gaps = 26/207 (12%)

Query: 2174 GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDS---CATT 2230
            GLCG  +GD  +D T +  SV  GA +   F +SW+     +      F  DS   C   
Sbjct: 1450 GLCGNNNGDLKDDFTTRYSSVASGALE---FGNSWKTSQECSDTVAQTFPCDSNPYCKAW 1506

Query: 2231 DCSPCLRMVSNRTFSACHRFVPPESFCELWIRDT-------KYVQQPCVALTVYVAMCHK 2283
                C  ++ + TF  CH  V P ++ ++ I +        KY+   C A+ +Y   C  
Sbjct: 1507 AVRKC-EILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGF-CTAVAMYAEACSA 1564

Query: 2284 FHVCIEWRRSDYCPFLCSSDSTYQACVTACEP-----PKTCQDGILGPLDPEHCQVLGEG 2338
              VC+ WR+ + CP  C   +    C    EP      KTC+D ++G    +    L EG
Sbjct: 1565 VGVCVSWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVG----QKFSSLLEG 1620

Query: 2339 CV--CSEGTILHRRHSALCIPEAKCAC 2363
            C   C +       ++  C+  ++C+C
Sbjct: 1621 CYAKCPDSAPYLDENTMKCVSLSECSC 1647



 Score = 73.6 bits (179), Expect = 3e-12
 Identities = 128/545 (23%), Positives = 196/545 (35%), Gaps = 82/545 (15%)

Query: 1336 CEWRYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCP-TPQVLDEVTQRCVYLEDC--- 1391
            C W Y+ C +   +TC+D +    +    +EGC   CP +   LDE T +CV L +C   
Sbjct: 1590 CRWHYEPCGTVTAKTCKD-QLVGQKFSSLLEGCYAKCPDSAPYLDENTMKCVSLSECSCF 1648

Query: 1392 ---VEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTAL 1448
               V PA  V  +  G  T     G    S+  P  S  +  T T    L+  A +T   
Sbjct: 1649 YNDVIPAGGVIEDNCG-RTCYCIAGQLECSETAPTNSTFAVSTTTATTILSTGAAITLVT 1707

Query: 1449 NPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSS 1508
              P TA   P ++   ++TT              GP   P + G+T + + I  T  ++ 
Sbjct: 1708 GGPSTAASIPAITTSSSETT----------GTTLGPLTEPFTTGITETSVPIISTSGNAG 1757

Query: 1509 LPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLP 1568
            +   +     G    A  T  V     G+ +   S R+   PR    T AV   G GS P
Sbjct: 1758 MTGVVSPTVTGASGMAGTTGGVDAATTGAASENTSERA-GTPRVSGETPAV---GGGSTP 1813

Query: 1569 VRTTPLQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQS 1628
                P      A+ S     S G+I+ SP +S         A +   S++G   P+    
Sbjct: 1814 GEAGP-----GATVSGSTGVSAGSITASPGAS---------ATSSESSKSGTTGPSVGGK 1859

Query: 1629 ASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAP 1688
              + S+  T +   +     S  +T   +  ++ +    G      SP      P P +P
Sbjct: 1860 TGATSSEATSSEGMSGVTGQSLGSTAGSDSEITAKTSFTG-----SSPPGKLTRPSPGSP 1914

Query: 1689 PRPAQHTT------------------MATRSPALPPETPAAASLSTATDG---------- 1720
               +  TT                  + +   ++   T A +  +  T G          
Sbjct: 1915 GHFSGGTTEWGNVATTGAAGENTSGALGSTEGSVEATTSAGSGNTAGTSGTGDTGPGNTA 1974

Query: 1721 LAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAPVA----TPGPKASVITTPLQPQA 1776
            ++ TP +S  +T P    S  P +  +     G S        T    A +  TP    A
Sbjct: 1975 VSGTPVVSPGAT-PGAPGSSTPGEADIGNTSFGKSGKSGHDSLTVLNPAFLRRTPTVSAA 2033

Query: 1777 TTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASM 1836
            +T    T SPV   T AA   A   +   P   GT  G   G  + TSG    + GT++ 
Sbjct: 2034 ST----TSSPVSKHTDAASATAVTISGSKPGTPGTPGGATSGGKI-TSGW--SSSGTSTG 2086

Query: 1837 VSVVP 1841
             S  P
Sbjct: 2087 ASNTP 2091



 Score = 49.7 bits (117), Expect = 4e-05
 Identities = 91/424 (21%), Positives = 152/424 (35%), Gaps = 59/424 (13%)

Query: 1975 TSTTCVPIAEQDCVRHI-CLEGQLIR-VNQSQHCPQGAAPPRCGILGLAVRVG------- 2025
            T +   P  + +CV    C EG L+  + +   C   A  P C   G   + G       
Sbjct: 778  TCSNVAPFQDSECVSGCTCPEGYLLDDIGEKGKCVLKAECP-CESSGTVYQPGEVREGPC 836

Query: 2026 GDRC--------CPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHV 2077
            G +C        C    C  RC +    S  TFDG          ++   + D  ++V +
Sbjct: 837  GSQCTCQDAKWSCTEALCPGRCKV-EGSSLTTFDGVKYNFPGNCHFLAVHNEDWSISVEL 895

Query: 2078 LDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDR--FNRKVTVDLQPVWPPVSRYGFRIE 2135
              C S   G       CL  + +  L   V +D+  FN   TV    +      Y  +I+
Sbjct: 896  RPCPSGQTGT------CLNSVTLL-LNSSVPVDKYVFNSDGTVTNDKIRNQGYYYSDKIQ 948

Query: 2136 --DTGHMYMILTPS---DIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLK 2190
              +    Y+ +       +QIQ +    L  V           GLCG  +  A +D    
Sbjct: 949  IFNASSSYLQVETYFHVKLQIQIVPVMQLY-VSMPPNQFTDTVGLCGSYNNKAEDDFMSS 1007

Query: 2191 DGSVVGGAEDPAPFLDSWQV-------PSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRT 2243
               +   ++    F +SW++       PSS  S+ + +F    C        + + S+  
Sbjct: 1008 QNILEKTSQ---AFANSWEMMSCPKGNPSSCISIEKEKFAERHCG-------ILLDSSGP 1057

Query: 2244 FSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCIEWRRSDYCPFL 2299
             ++CH  V P+ + E   + T   +      C  L  YV  C +    I   R+  C   
Sbjct: 1058 LASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHS 1117

Query: 2300 CSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEA 2359
            C S   ++  V AC              D E   V  +GC C +   +++ +   C+ ++
Sbjct: 1118 CPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPV--DGCTCPDA--MYQNNEGNCVLKS 1173

Query: 2360 KCAC 2363
            +C C
Sbjct: 1174 QCDC 1177


>gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]
          Length = 2639

 Score =  430 bits (1105), Expect = e-119
 Identities = 243/698 (34%), Positives = 377/698 (54%), Gaps = 39/698 (5%)

Query: 498  SVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYD 557
            +V+L  D ++ V + ++   +L ++ ++  P+   +F + R SS  + V   +GVR+   
Sbjct: 347  TVVLLADKKKNVVVFKSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQ 406

Query: 558  REG-LRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSP 616
                ++L++ +DQ       GLCG FNG   DDF +  G+ E+T   F N+WK  S+C  
Sbjct: 407  LAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHD 466

Query: 617  LVSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDACRC--G 672
             +     DPC +++++A+Y+   CS+L  T   F  C + + P  Y+++C+ D C C   
Sbjct: 467  KLDWLD-DPCSLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNN 525

Query: 673  QPCLCATLAHYAHLCRRHGLPVDFRARLPACAL---SCEASKEYSPCVAPCGRTCQDLAS 729
            + CLCA L+ YA  C   G+ + +  R   C     SC  S+ +   +  C +TC+ L+ 
Sbjct: 526  EDCLCAALSSYARACTAKGVML-WGWREHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSE 584

Query: 730  PEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPS 789
             ++  ++G         V+GC CP  T+LD +   CVP  +CSC+ +G+    GD  +  
Sbjct: 585  ADSHCLEGFAP------VDGCGCPDHTFLDEKGR-CVPLAKCSCYHRGLYLEAGDVVVRQ 637

Query: 790  LGHCHCKDGVMSCDS-RAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARG 848
               C C+DG + C   R    +C A ++ ++CS+L T L  S+ R    Q L        
Sbjct: 638  EERCVCRDGRLHCRQIRLIGQSCTAPKIHMDCSNL-TALATSKPRALSCQTLAAGYY-HT 695

Query: 849  PCLSGCACPQGLLRHG-DACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLH 907
             C+SGC CP GL+  G   C + +ECPC      Y  G ++   C+TC C+RG + CT  
Sbjct: 696  ECVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQA 755

Query: 908  PCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVK-----STSDVSFSVIVENVNCYSSGM 962
             C  TC+ YG  HY TFDG  +DF G C    V+     ++S  SFS+I ENV C ++G+
Sbjct: 756  VCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGV 815

Query: 963  ICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVH-----TWRVGFFTLVHFPQEHIT 1017
             C K I I +G + +  +D          +  + E H     T  VG + +V      I 
Sbjct: 816  TCSKAIKIFMGRTELKLEDK------HRVVIQRDEGHHVAYTTREVGQYLVVE-SSTGII 868

Query: 1018 LLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWA-AVEC 1076
            ++WD+RTTV ++  P ++G + GLCGNFD ++ N+  T +++ +++  +FG+SW  A  C
Sbjct: 869  VIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTC 928

Query: 1077 PDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGD 1136
            PD     + C LNP R  +A+K+CSIL S VF ICH  VD   FY  C+ D+C C  GGD
Sbjct: 929  PDVSTNPEPCSLNPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGD 988

Query: 1137 CECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFN 1174
            CECFC++V++YA +C + G  V WRTP LCP  CD++N
Sbjct: 989  CECFCSAVASYAQECTKEGACVFWRTPDLCPIFCDYYN 1026



 Score =  237 bits (605), Expect = 1e-61
 Identities = 319/1356 (23%), Positives = 478/1356 (35%), Gaps = 232/1356 (17%)

Query: 1380 EVTQRCVYLEDCVEPAVWVPTEALGNETLPP----SQGLPTPSDEEPQLSQESP--RTPT 1433
            E+  +C    +CV     + T    N T  P    +   PTP+    Q +  +P   T T
Sbjct: 1288 EINVQCC---ECVTQPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTT 1344

Query: 1434 HRPALTPAAPLTTALNP-PVTATEEPVVSPGPTQTTLQQPLELTASQLPAGP---TESPA 1489
              P  TP    T    P   T T  P  +P  TQT    P+  T +  P      T++P 
Sbjct: 1345 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 1404

Query: 1490 SKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPA 1549
            S  +T +    P TP     P   QTPT         TT +T     +P  T +    P 
Sbjct: 1405 STPITTTTTVTP-TPT----PTGTQTPT---------TTPITTTTTVTPTPTPTGTQAPT 1450

Query: 1550 PRFPLMTKAVTVRGHGSLPVRTTPLQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTP 1609
            P     T  VT           TP  P+ T +P++ P+ +   ++ +PT +G+     TP
Sbjct: 1451 PTAITTTSTVT----------PTPT-PTGTQTPTTTPITTTTTVTPTPTPTGTQ----TP 1495

Query: 1610 AVTKVISRTGV-PQPTQAQSASSPSTPLTVAGTAAE-------QVPV-SPLATRSLEIVL 1660
              T + + T V P PT   + +  STP+T   T          Q P  +P++T +     
Sbjct: 1496 TPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPT 1555

Query: 1661 STEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATD 1719
             T  G +   + P+ +  +  P P P+    P     + T +   P  TP      T+T 
Sbjct: 1556 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-VLITTTTTMTPTPTP------TSTK 1608

Query: 1720 GLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAPVATP-----GPKASVITTPLQP 1774
                TP  +  +   +   +G    T +P++   T  P  TP     GP     T P+  
Sbjct: 1609 STTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAE 1668

Query: 1775 QATTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTA 1834
              T+ P                   PP    P  + +    L  +T   S + P  E T+
Sbjct: 1669 LTTSNP-------------------PPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709

Query: 1835 SMVSVVPRKSTTGKVAILSKQVSLPTSMYGSAEGGPTE-LTPATSHPLTPLVAEPEGAQA 1893
            +     P   TT         +S P S   S  G PT   T  +S   TP   +     A
Sbjct: 1710 TAPPSTPTAPTTTSGG---HTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSA 1766

Query: 1894 GTALPVPTSYALSRVSARTAPQDSMLVLLPQLAEAH---------GTSAGPHLAAEPVDE 1944
             T  P P S      +    P  S +++   L + +         GT             
Sbjct: 1767 WTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLS 1826

Query: 1945 ATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVPIAEQ------------------- 1985
             T E    S P+             T    +ST   P                       
Sbjct: 1827 CTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECPDFDPPRQENETWW 1886

Query: 1986 --DCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGG-DRCCPLWECACRCSIF 2042
              DC    C     + + + +  P     P C      VRV   D CC  WEC C C+ +
Sbjct: 1887 LCDCFMATCKYNNTVEIVKVECEPPPM--PTCSNGLQPVRVEDPDGCCWHWECDCYCTGW 1944

Query: 2043 PDLSFVTFDGSHVALFKEAIYILSQ--SPDEMLTVHVLDCKSANLGHLNWPP----FCLV 2096
             D  +VTFDG + +      Y+L +  SP        +D     + + +  P     C  
Sbjct: 1945 GDPHYVTFDGLYYSYQGNCTYVLVEEISPS-------VDNFGVYIDNYHCDPNDKVSCPR 1997

Query: 2097 MLNMTHLAHQVTIDRFNR-----KVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQI 2151
             L + H   +V I   +      +V V+ Q V  P  +YG  +  +G  Y++  P    +
Sbjct: 1998 TLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVL 2057

Query: 2152 QWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVP 2211
               +     +            G CG C    ++D  L  G +V   E  A   D W V 
Sbjct: 2058 VSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAA---DQWLVN 2114

Query: 2212 ---------SSLTSVGQTRFRPDSCATT---DC--SPCLRMVSNRTFSACHRFVPPESFC 2257
                     SS T+       P    TT   DC  SP  +++ +  F+ CH  VPP+ + 
Sbjct: 2115 DPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYY 2174

Query: 2258 ELWIRDTKYV---QQPCVALTVYVAMCHKFHVCIEWRRSDY--CPFLCSSDSTYQACVTA 2312
            +  + D+ ++      C +L  Y A+C + ++C++WR   +  C   C S   YQAC  A
Sbjct: 2175 DACVFDSCFMPGSSLECASLQAYAALCAQQNICLDWRNHTHGACLVECPSHREYQACGPA 2234

Query: 2313 CEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRA 2372
             EP  TC+         ++  VL EGC C EGT+ +     +C+    C C     VPR 
Sbjct: 2235 EEP--TCKSSS----SQQNNTVLVEGCFCPEGTMNYAPGFDVCVKT--CGCVGPDNVPRE 2286

Query: 2373 LGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGE-VALLLPTKDPCCLGTV 2431
             GE +      C     +    I+     C       C+  G  +A  +   D CC  TV
Sbjct: 2287 FGEHFEFDCKNCVC--LEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTCCNITV 2344

Query: 2432 CVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCECDPDLC---EAELVPSCRQDQIL 2488
            C CN +LC+     C  G  + +      CCP Y CE    +C    AE  P        
Sbjct: 2345 CKCNTSLCKEKPSVCPLGFEVKSKMVPGRCCPFYWCE-SKGVCVHGNAEYQPG------- 2396

Query: 2489 ITGRLGDSCCTSYFCACGDCPDSIPECQEGEALTVHRNTTELCCPLYQCVCENFRCPQVQ 2548
                        Y   C DC      C +     V  NT      L    C +  C    
Sbjct: 2397 ---------SPVYSSKCQDC-----VCTD----KVDNNTL-----LNVIACTHVPC-NTS 2432

Query: 2549 CGLGTALVEVWSPDRCCPYKSCE---C---------------DCDTIPVPRCHLWEKSQL 2590
            C  G  L+E  +P  CC  K CE   C               D  + P   C  +   ++
Sbjct: 2433 CSPGFELME--APGECC--KKCEQTHCIIKRPDNQHVILKPGDFKSDPKNNCTFFSCVKI 2488

Query: 2591 DEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPG 2626
              + + SV N+  C  ++   A +C+   +  M  G
Sbjct: 2489 HNQLISSVSNIT-CPNFD---ASICIPGSITFMPNG 2520



 Score =  231 bits (589), Expect = 8e-60
 Identities = 190/769 (24%), Positives = 312/769 (40%), Gaps = 164/769 (21%)

Query: 158  MRVQLPHVMGSARLQQLAGYVIVRHQSA---FTLAWDGASAVYIKMSPELLGWTHGLCGN 214
            ++V LPHV  S  + + + Y I+   +      +       +++ +     G   GLCGN
Sbjct: 372  LQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGLCGN 431

Query: 215  NNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVY 274
             N    DD  T+SG +      F ++W+ Q+               PC   N  +     
Sbjct: 432  FNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKLDWLDD----PC-SLNIESANYAE 486

Query: 275  EQCEALLRP--PFDACHAYVSPLPF-------TASCTSD---LCQSMGD---------VA 313
              C  L +   PF  CH+ V P  +       T +C ++   LC ++           V 
Sbjct: 487  HWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGVM 546

Query: 314  TW------------------------------CRALAEYARACAQAGRPLQGW------- 336
             W                              CR+L+E    C +   P+ G        
Sbjct: 547  LWGWREHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGCPDHTF 606

Query: 337  ---------------------------------RTQLRQCTVHCKEKAFTYNECIA---- 359
                                             R   R   +HC++       C A    
Sbjct: 607  LDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEERCVCRDGRLHCRQIRLIGQSCTAPKIH 666

Query: 360  ------CCPASCHPRASCVDSEIA------CVDGCYCPNGLIFED-GGCVAPAECPCEFH 406
                     A+  PRA    +  A      CV GC CP+GL+ +  GGCV   ECPC  +
Sbjct: 667  MDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDGLMDDGRGGCVVEKECPCVHN 726

Query: 407  GTLYPPGSVVKEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYI 466
              LY  G+ +K DCNTCTC  G+W C+ AVC   CS+ G  H+ TFDG+ Y F   C Y+
Sbjct: 727  NDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYV 786

Query: 467  -----LAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFD 521
                   ++ S G+F++  +N PCG      C +++ + + +            ++ L D
Sbjct: 787  AVQDYCGQNSSLGSFSIITENVPCG-TTGVTCSKAIKIFMGRT-----------ELKLED 834

Query: 522  QYKIIPPYTDD---AFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGL 578
            +++++    +    A+  R +   +L V ++ G+ V++D+    +++++   +     GL
Sbjct: 835  KHRVVIQRDEGHHVAYTTREVGQ-YLVVESSTGIIVIWDKR-TTVFIKLAPSYKGTVCGL 892

Query: 579  CGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQ 638
            CG F+  + +DF +   +  S+   FGNSWK    C P VS +P +PC ++    S++ +
Sbjct: 893  CGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTC-PDVSTNP-EPCSLNPHRRSWAEK 950

Query: 639  ACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQ----PCLCATLAHYAHLCRRHGLPV 694
             CS+L   +F+ C + + P P++E C  D+C C       C C+ +A YA  C + G  V
Sbjct: 951  QCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACV 1010

Query: 695  DFRARLPACALSC-------EASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECV 747
             +R     C + C       E    Y PC      TC+ +      G+     +S    +
Sbjct: 1011 FWRTP-DLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTIN-----GIHSNISVS---YL 1061

Query: 748  EGC--ACPPDTYL-DTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHC 793
            EGC   CP D  + +     CV  ++C C+ +   YPPG S +P+   C
Sbjct: 1062 EGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGAS-VPTEETC 1109



 Score =  157 bits (398), Expect = 1e-37
 Identities = 125/396 (31%), Positives = 180/396 (45%), Gaps = 40/396 (10%)

Query: 79   CRAWGQHHVETFDGLYYYLSGKGSYTLV----GRHEPEGQSFSIQVHNDPQCGSSPYTCS 134
            C  +G  H  TFDG YY   G  SY  V    G++   G SFSI   N P CG++  TCS
Sbjct: 761  CSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLG-SFSIITENVP-CGTTGVTCS 818

Query: 135  RAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGAS 194
            +A+ +F +G  E+ L  +      R +  HV  + R  ++  Y++V   +   + WD  +
Sbjct: 819  KAIKIF-MGRTELKLEDKHRVVIQRDEGHHVAYTTR--EVGQYLVVESSTGIIVIWDKRT 875

Query: 195  AVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTT 254
             V+IK++P   G   GLCGN +    +D  T    +    ++F +SW+E     P  P  
Sbjct: 876  TVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKE----APTCPDV 931

Query: 255  SSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSD--LCQSMGDV 312
            S+ P P  L  NP       +QC  L    F  CH+ V P PF  +C  D   C + GD 
Sbjct: 932  STNPEPCSL--NPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDC 989

Query: 313  ATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHC------KEKAFTYNECIACCPASCH 366
              +C A+A YA+ C + G  +  WRT    C + C       E  + Y  C      +C 
Sbjct: 990  ECFCSAVASYAQECTKEGACV-FWRTP-DLCPIFCDYYNPPHECEWHYEPCGNRSFETCR 1047

Query: 367  P-RASCVDSEIACVDGCY--CPNGL-IFEDG--GCVAPAECPCEFHGTLYPPGSVV--KE 418
                   +  ++ ++GCY  CP    I+E+    CV   +C C    T YPPG+ V  +E
Sbjct: 1048 TINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGASVPTEE 1107

Query: 419  DCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDG 454
             C +C CT+     S  VC  E    G I   T DG
Sbjct: 1108 TCKSCVCTNS----SQVVCRPE---EGKILNQTQDG 1136



 Score =  119 bits (297), Expect = 6e-26
 Identities = 139/580 (23%), Positives = 226/580 (38%), Gaps = 108/580 (18%)

Query: 403  CEFHGTLYPPGSVVKEDCNTC---TCTSG--------------KWECSTAVCPAECSVTG 445
            C+++ T+     +VK +C      TC++G               WEC        C+  G
Sbjct: 1895 CKYNNTV----EIVKVECEPPPMPTCSNGLQPVRVEDPDGCCWHWECD-----CYCTGWG 1945

Query: 446  DIHFTTFDGRRYTFPATCQYILAK--SRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQ 503
            D H+ TFDG  Y++   C Y+L +  S S   F V + N  C  N   +C +++ ++ H+
Sbjct: 1946 DPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSCPRTL-IVRHE 2004

Query: 504  DPR---RQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREG 560
                  + V +      +  ++  +  PY     E+ +    ++     +GV V Y+  G
Sbjct: 2005 TQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVLVSYN--G 2062

Query: 561  LRLYLQVD-QRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLV- 618
            L   +++   R+  +T G CGT    T DD + P G   S  +   + W       P   
Sbjct: 2063 LSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCP 2122

Query: 619  -SGSPLDPCDVHLQAASYSV--------QACSVLTGEMFAPCSAFLSPVPYFEQCRRDAC 669
             S S      V +     +           C ++   +FA C A + P  Y++ C  D+C
Sbjct: 2123 HSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSC 2182

Query: 670  -RCGQPCLCATLAHYAHLCRRHGLPVDFRARL-PACALSCEASKEYSPCVAPCGRTCQDL 727
               G    CA+L  YA LC +  + +D+R     AC + C + +EY  C      TC+  
Sbjct: 2183 FMPGSSLECASLQAYAALCAQQNICLDWRNHTHGACLVECPSHREYQACGPAEEPTCKSS 2242

Query: 728  ASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQA-DLCVPRNQCSCHFQGVDYPP---G 783
            +S +          +    VEGC CP  T       D+CV    C C   G D  P   G
Sbjct: 2243 SSQQ----------NNTVLVEGCFCPEGTMNYAPGFDVCV--KTCGC--VGPDNVPREFG 2288

Query: 784  DSDIPSLGHCHCKDG--VMSCD----SRAPAAACPAGQVF----VNCSDLHTDLELSRER 833
            +       +C C +G   + C     S+ P   C     +    VN +D   ++ + +  
Sbjct: 2289 EHFEFDCKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTCCNITVCKCN 2348

Query: 834  T--CEQQ--LLNLSVSARGPCLSGCACP------QGLLRHGDACFLPEECPCTWKGKEYF 883
            T  C+++  +  L    +   + G  CP      +G+  HG+A              EY 
Sbjct: 2349 TSLCKEKPSVCPLGFEVKSKMVPGRCCPFYWCESKGVCVHGNA--------------EYQ 2394

Query: 884  PGDQV-MSPCHTCVCQ--------RGSFQCTLHPCASTCT 914
            PG  V  S C  CVC              CT  PC ++C+
Sbjct: 2395 PGSPVYSSKCQDCVCTDKVDNNTLLNVIACTHVPCNTSCS 2434



 Score =  115 bits (289), Expect = 5e-25
 Identities = 109/399 (27%), Positives = 155/399 (38%), Gaps = 49/399 (12%)

Query: 74   ERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTC 133
            E D  C  WG  H  TFDGLYY   G  +Y LV    P   +F + + N     +   +C
Sbjct: 1936 ECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSC 1995

Query: 134  SRAVSLFFVGEQEIHLAKEVTHGGMRVQ---------LPH-VMGSARLQQLAGYVIVRHQ 183
             R  +L    E +  L K V    M+VQ         LP+   G    Q    YV+   +
Sbjct: 1996 PR--TLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPE 2053

Query: 184  SAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQE 243
                ++++G S             T G CG       DD +  SG++  +       W  
Sbjct: 2054 LGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLV 2113

Query: 244  QAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQ------CEALLRPPFDACHAYVSPLPF 297
              P++P  P +SS  + P +    G     ++       C+ +    F  CHA V P  +
Sbjct: 2114 NDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHY 2173

Query: 298  TASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLR-QCTVHCKEKAFTYNE 356
              +C  D C   G  +  C +L  YA  CAQ    L  WR      C V C     ++ E
Sbjct: 2174 YDACVFDSCFMPGS-SLECASLQAYAALCAQQNICLD-WRNHTHGACLVECP----SHRE 2227

Query: 357  CIACCPA---SCHPRASCVDSEIACVDGCYCPNG---------LIFEDGGCVAPAECPCE 404
              AC PA   +C   +S  ++ +  V+GC+CP G         +  +  GCV P   P E
Sbjct: 2228 YQACGPAEEPTCKSSSSQQNNTV-LVEGCFCPEGTMNYAPGFDVCVKTCGCVGPDNVPRE 2286

Query: 405  FHGTLYPPGSVVKEDCNTCTCTSGKWECSTAVC-PAECS 442
            F       G   + DC  C C  G    S  +C P  CS
Sbjct: 2287 F-------GEHFEFDCKNCVCLEGG---SGIICQPKRCS 2315



 Score =  109 bits (273), Expect = 3e-23
 Identities = 91/329 (27%), Positives = 145/329 (44%), Gaps = 32/329 (9%)

Query: 441 CSVTGDIHFTTFDGRRYTFPATCQYILAKS--RSSGTFTVTLQNAPCGLNQDGACVQSVS 498
           CS  G+ H+ TFDG  + FP  C Y  A     S   F V L+  P G  +  A V+S+ 
Sbjct: 37  CSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGP-GQAEAPAGVESIL 95

Query: 499 VILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDR 558
           + +  D     T+     + + +   +  P+      I + S  + +V +  G+ ++++R
Sbjct: 96  LTIKDD-----TIYLTRHLAVLNGAVVSTPHYSPGLLIEK-SDAYTKVYSRAGLTLMWNR 149

Query: 559 EGLRLYLQVDQRWVEDTVGLCGTFNG-NTQDDFLSPVGVPESTPQLFGNSWKTLSACSPL 617
           E   L L++D ++   T GLCG +NG  +  +FLS  GV  S P  FGN  K       +
Sbjct: 150 ED-ALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSD-GVLFS-PLEFGNMQKINQ--PDV 204

Query: 618 VSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRC--GQPC 675
           V   P +        + +  +   +LT E FA C   +   PY   C++D CRC  G  C
Sbjct: 205 VCEDPEEEV-APASCSEHRAECERLLTAEAFADCQDLVPLEPYLRACQQDRCRCPGGDTC 263

Query: 676 LCATLAHYAHLC-RRHGLPVDFR----ARLPACALSCEASKEYSPCVAPCGRTCQDLASP 730
           +C+T+A ++  C    G P ++R    A  P  + +C  +  Y    +PC  TC  L   
Sbjct: 264 VCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTCSHLEVS 323

Query: 731 EACGVDGGDDLSRDECVEGCACPPDTYLD 759
             C          +  ++GC CP     D
Sbjct: 324 SLC---------EEHRMDGCFCPEGAQAD 343



 Score =  104 bits (259), Expect = 1e-21
 Identities = 154/720 (21%), Positives = 245/720 (34%), Gaps = 105/720 (14%)

Query: 1336 CEWRYDACASPCFQTCRDPRAA-SCRDVPRVEGCVPVCPTPQ-VLDEVTQRCVYLEDC-- 1391
            CEW Y+ C +  F+TCR      S   V  +EGC P CP  + + +E  ++CV  + C  
Sbjct: 1031 CEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGC 1090

Query: 1392 ------VEPAVWVPTEALGNETLPPSQGLPTPSDEEPQ-LSQESPRTPTHRPALTPAAPL 1444
                    P   VPTE      +  +        EE + L+Q       +     P   +
Sbjct: 1091 YVEDTHYPPGASVPTEETCKSCVCTNSSQVVCRPEEGKILNQTQDGAFCYWEICGPNGTV 1150

Query: 1445 TTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTP 1504
                N     T    ++   T T    P   T +     PT S            +  TP
Sbjct: 1151 EKHFNICSITTRPSTLTTFTTITLPTTPTTFTTTTTTTTPTSS----------TVLSTTP 1200

Query: 1505 ESSSL---PVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFP-------- 1553
            +   L    +    P+ G   G  ET        G+P   +  RS   P           
Sbjct: 1201 KLCCLWSDWINEDHPSSGSDDGDRETFDGV---CGAPE-DIECRSVKDPHLSLEQLGQKV 1256

Query: 1554 ---------LMTKAVTVRGHGSLPV-----------------RTTPLQPSLTASPSSRPV 1587
                     L+ K    +  G +P+                 + T +  + T +P+  P+
Sbjct: 1257 QLVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPTPI 1316

Query: 1588 ASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGT------ 1641
             +   ++ +PT + +     TP  T   + T  P PT   + +  +TP+T   T      
Sbjct: 1317 TTTTTVTPTPTPTSTQSTTPTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 1373

Query: 1642 -AAEQVP-VSPLATRSLEIVLSTEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQHTTMA 1698
                Q P  +P+ T +      T  G +   S P+ +  +  P P P+    P   T + 
Sbjct: 1374 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTT-TPIT 1432

Query: 1699 TRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAP- 1757
            T +   P  TP      T T     T   +  +  P+   +G    T+ P+    T  P 
Sbjct: 1433 TTTTVTPTPTP------TGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPT 1486

Query: 1758 -----VATPGPKASVITTPLQP--------QATTLPAQTLSPVLPFTPAAMTQAHPPTHI 1804
                   TP P A   TT + P          T+ P  T + V P      TQ   PT I
Sbjct: 1487 PTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPI 1546

Query: 1805 APPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSL-PTSMY 1863
            +     T      G   PT+   P+   T    +  P  + T    +++   ++ PT   
Sbjct: 1547 STTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTP 1604

Query: 1864 GSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDS--MLVL 1921
             S +   T +TP T+         P G Q  T +P+ T+  ++     T           
Sbjct: 1605 TSTKS--TTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTS 1662

Query: 1922 LPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 1981
               +AE   ++  P  +      +T+ P   S   LS    L  A+  T+ A  ST   P
Sbjct: 1663 TAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLST---LPPAIEMTSTAPPSTPTAP 1719



 Score = 91.3 bits (225), Expect = 1e-17
 Identities = 78/317 (24%), Positives = 124/317 (39%), Gaps = 18/317 (5%)

Query: 77  SICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRA 136
           ++C  WG  H +TFDG  +   G   Y          + F++ +   P    +P      
Sbjct: 35  NVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQAEAPAGVESI 94

Query: 137 VSLFFVGEQEIHLAKEVTH-GGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASA 195
             L  + +  I+L + +    G  V  PH      +++   Y  V  ++  TL W+   A
Sbjct: 95  --LLTIKDDTIYLTRHLAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLTLMWNREDA 152

Query: 196 VYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTS 255
           + +++  +    T GLCG+ N         S G L   + EF +    Q  NQP      
Sbjct: 153 LMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPL-EFGNM---QKINQP-----D 203

Query: 256 SLPRPPCLQQNPGTMQGVYEQCEALLRPP-FDACHAYVSPLPFTASCTSDLCQSMGDVAT 314
            +   P  +  P +      +CE LL    F  C   V   P+  +C  D C+  G    
Sbjct: 204 VVCEDPEEEVAPASCSEHRAECERLLTAEAFADCQDLVPLEPYLRACQQDRCRCPGGDTC 263

Query: 315 WCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKA---FTYNECIACCPASC-HPRAS 370
            C  +AE++R C+ AG     WRT     +    +       Y E  + C  +C H   S
Sbjct: 264 VCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTCSHLEVS 323

Query: 371 CVDSEIACVDGCYCPNG 387
            +  E   +DGC+CP G
Sbjct: 324 SLCEEHR-MDGCFCPEG 339



 Score = 75.5 bits (184), Expect = 7e-13
 Identities = 70/313 (22%), Positives = 118/313 (37%), Gaps = 46/313 (14%)

Query: 904  CTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVK--STSDVSFSVIVENVNCYSSG 961
            C    C   CT +GD HY TFDGL + + G C   LV+  S S  +F V ++N +C  + 
Sbjct: 1932 CWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPND 1991

Query: 962  MI-CRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEV---------HTWRVGFFTLVHF 1011
             + C + + +      ++       P       ++Q V           ++ G   +V  
Sbjct: 1992 KVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDI 2051

Query: 1012 PQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSW 1071
            P+  + + ++  +        ++     G CG     T ++   P    ++N +     W
Sbjct: 2052 PELGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQW 2111

Query: 1072 AAVE-----CPDTLD----------------PRDMCVLNPLREPFAKKECSILLSEVFEI 1110
               +     CP +                  P   C  +PL        C ++   +F  
Sbjct: 2112 LVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPL--------CQLIKDSLFAQ 2163

Query: 1111 CHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWR--TPRLCPY 1168
            CH +V    +Y  C+ D+C    G   EC  AS+ AYA  C Q  + +DWR  T   C  
Sbjct: 2164 CHALVPPQHYYDACVFDSC-FMPGSSLEC--ASLQAYAALCAQQNICLDWRNHTHGACLV 2220

Query: 1169 DCDFFNKVLGKGP 1181
            +C    +    GP
Sbjct: 2221 ECPSHREYQACGP 2233



 Score = 67.4 bits (163), Expect = 2e-10
 Identities = 89/398 (22%), Positives = 145/398 (36%), Gaps = 67/398 (16%)

Query: 2030 CPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDC-KSANLGHL 2088
            C    C   CSI+    ++TFDG +        Y+  Q            C ++++LG  
Sbjct: 752  CTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDY----------CGQNSSLGS- 800

Query: 2089 NWPPFCLVMLNM----THLAHQVTIDRFNRKVTVDLQPVWPPVSR------YGFRIEDTG 2138
                F ++  N+    T +     I  F  +  + L+     V +        +   + G
Sbjct: 801  ----FSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYTTREVG 856

Query: 2139 HMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGA 2198
               ++ + + I + W      + ++ + + K    GLCG  D  + ND T +D  VV   
Sbjct: 857  QYLVVESSTGIIVIW-DKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSE 915

Query: 2199 EDPAPFLDSWQVPSSLTSVGQTRFRPDSC---------ATTDCSPCLRMVSNRTFSACHR 2249
             D   F +SW+   +   V      P+ C         A   CS    ++ +  FS CH 
Sbjct: 916  LD---FGNSWKEAPTCPDVSTN---PEPCSLNPHRRSWAEKQCS----ILKSSVFSICHS 965

Query: 2250 FVPPESFCELWIRDTKYVQQP------CVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSD 2303
             V P+ F E  + D+            C A+  Y   C K   C+ WR  D CP  C   
Sbjct: 966  KVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACVFWRTPDLCPIFCDYY 1025

Query: 2304 STYQACVTACEPP-----KTCQ--DGILGPLDPEHCQVLGEGCV--CSEGTILHRRHSAL 2354
            +    C    EP      +TC+  +GI   +   +     EGC   C +   ++      
Sbjct: 1026 NPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYL----EGCYPRCPKDRPIYEEDLKK 1081

Query: 2355 CIPEAKCAC--TDSMGVPRALGETWNSSLSGCCQHQCQ 2390
            C+   KC C   D+   P A   T  +  S  C +  Q
Sbjct: 1082 CVTADKCGCYVEDTHYPPGASVPTEETCKSCVCTNSSQ 1119



 Score = 66.6 bits (161), Expect = 3e-10
 Identities = 66/274 (24%), Positives = 120/274 (43%), Gaps = 43/274 (15%)

Query: 911  STCTAYGDRHYRTFDGLPFDFVGACK---------------VHLVKSTSDVSFSVIVENV 955
            + C+ +G+ HY+TFDG  F F G C                VHL +          VE++
Sbjct: 35   NVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQAEAPAGVESI 94

Query: 956  NCYSSGMICRKFISINVGNSLIVFDD---DSGNPSPESFLDDKQEVHTWRVGFFTLVHFP 1012
                  ++  K  +I +   L V +     + + SP   L +K + +T          + 
Sbjct: 95   ------LLTIKDDTIYLTRHLAVLNGAVVSTPHYSP-GLLIEKSDAYT--------KVYS 139

Query: 1013 QEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFD-LKTINEMRTPENLELTNPQEFGSSW 1071
            +  +TL+W++   + ++   +++    GLCG+++ L++ +E  +     L +P EFG+  
Sbjct: 140  RAGLTLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDG--VLFSPLEFGNM- 196

Query: 1072 AAVECPDTL--DPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTC 1129
              +  PD +  DP +        E  A+ E  +L +E F  C  +V +  +   C  D C
Sbjct: 197  QKINQPDVVCEDPEEEVAPASCSEHRAECE-RLLTAEAFADCQDLVPLEPYLRACQQDRC 255

Query: 1130 GCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRT 1162
             C  G    C C++V+ ++ QC   G    +WRT
Sbjct: 256  RCPGGD--TCVCSTVAEFSRQCSHAGGRPGNWRT 287



 Score = 51.6 bits (122), Expect = 1e-05
 Identities = 59/226 (26%), Positives = 84/226 (37%), Gaps = 39/226 (17%)

Query: 2160 MIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQ 2219
            + V   + S+ Q  GLCG  +G   +D     G V       A F ++W+  SS     +
Sbjct: 413  LFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATG---AGFANTWKAQSSCHD--K 467

Query: 2220 TRFRPDSCATTDCSP------CLRMVSNRT-FSACHRFVPPESFCELWIRDTKYVQQP-- 2270
              +  D C+    S       C  +    T F  CH  V P  + +    DT   Q    
Sbjct: 468  LDWLDDPCSLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNED 527

Query: 2271 --CVALTVYVAMCHKFHVCI-EWRRS------DYCP----FLCSSDSTYQACVTACEPPK 2317
              C AL+ Y   C    V +  WR          CP    FL +  +  Q C +  E   
Sbjct: 528  CLCAALSSYARACTAKGVMLWGWREHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADS 587

Query: 2318 TCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCAC 2363
             C +G   P+D         GC C + T L  +    C+P AKC+C
Sbjct: 588  HCLEGF-APVD---------GCGCPDHTFLDEK--GRCVPLAKCSC 621


>gi|239751787 PREDICTED: hypothetical protein XP_002348012 [Homo
            sapiens]
          Length = 3003

 Score =  310 bits (793), Expect = 2e-83
 Identities = 311/1220 (25%), Positives = 449/1220 (36%), Gaps = 196/1220 (16%)

Query: 49   HPAFCDCRRFNATGPRCQM---VYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTL 105
            H   C  ++    G RC +   +    P+R   C+  G  H  +FDG  +   G  +Y L
Sbjct: 831  HQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLL 890

Query: 106  VGRHEPEGQ--SFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLP 163
            VG         +F + V N+ + GS   + +RAV    V  + + +A    + G +V + 
Sbjct: 891  VGSCGQNAALPAFRVLVENEHR-GSQTVSYTRAVR---VEARGVKVAVRREYPG-QVLVD 945

Query: 164  HVMGSARLQQLAGYV---------IVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGN 214
             V+     Q   G V         +VR     T+ +D  + V  K+         GLCGN
Sbjct: 946  DVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGN 1005

Query: 215  NNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVY 274
             N DP DDL    G    + + F +SWQE+     PG   +     P L           
Sbjct: 1006 FNGDPADDLALRGGGQAANALAFGNSWQEETR---PGCGATEPGDCPKLDSLVAQQLQSK 1062

Query: 275  EQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRP 332
             +C  L  P  PF  CH+ + P      C  D C   G     C ALA YA AC  AG  
Sbjct: 1063 NECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGAT 1122

Query: 333  LQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFED 392
            +  WR++   C + C   +  Y  C   CP SC            C +GC C  G     
Sbjct: 1123 VHPWRSE-ELCPLSCPPHSH-YEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSG 1180

Query: 393  GGCVAPAECPCEFHGTLYPPGSVVKED--CNT-CTCTSGKW-ECSTAVC----------- 437
              C+  A C C   GT +PPG        C++ C C  G    C ++ C           
Sbjct: 1181 ESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGG 1240

Query: 438  --------PAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSS----GTFTVTLQNAPC 485
                     + C  +GD H+TTFDGRR+ F  TC Y+LA++  +      F V  +N   
Sbjct: 1241 SLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAW 1300

Query: 486  GLNQDGA----CVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS- 540
            G  +        VQ  +  L  + R+        D+ L        P      +IR    
Sbjct: 1301 GNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKL--------PVVLANGQIRASQH 1352

Query: 541  SVFLRVRTNVGVRVLYDREGLRLYLQ--VDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPE 598
               + + T+ G+RV YD   L  Y++  V   + +   GLCG +NG+ +DDF  P G   
Sbjct: 1353 GSDVVIETDFGLRVAYD---LVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQA 1409

Query: 599  STPQLFGNSWKTLSACSPLVSGSPLDP----------CDVHLQAASYSVQACSVLTGEM- 647
                 FGNSW+ +   SP +  +P  P          C   L+      + C +L+    
Sbjct: 1410 GNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTG 1469

Query: 648  -FAPCSAFLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACA 704
              + C   + P    + C  D C  G     LC+ +  Y   C+  G  V+       C 
Sbjct: 1470 PLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCP 1529

Query: 705  LSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADL 764
            + C  +  Y  C   C   C  L++P  C         +D C EGC C      + QA  
Sbjct: 1530 MECPPNSHYELCADTCSLGCSALSAPPQC---------QDGCAEGCQCDSGFLYNGQA-- 1578

Query: 765  CVPRNQCSCHFQGVDYPPGDS----DIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNC 820
            CVP  QC C+  GV Y P  +    +      CH   G M C       +C  GQV    
Sbjct: 1579 CVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKG-MVCQEH----SCKPGQV---- 1629

Query: 821  SDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGK 880
                          C+     LS   + PC            HG  C             
Sbjct: 1630 --------------CQPSGGILSCVTKDPC------------HGVTC------------- 1650

Query: 881  EYFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHL- 939
                      P  TC  Q G   C L    +TC  +GD HY +FDG  FDF G C   L 
Sbjct: 1651 ---------RPQETCKEQGGQGVC-LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLA 1700

Query: 940  ------VKSTSDVSFSVIVENVNCYSSGMICRKFISI-NVGNSLIVFDDDSG-------- 984
                  V +     F+V  +N N  +  +   + +++  +G ++ +  D+ G        
Sbjct: 1701 TTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNG 1760

Query: 985  --NPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLC 1042
                 P S  D +  V         +  F    + + +D    V V     + G + GLC
Sbjct: 1761 VLTALPVSVADGRISVAQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLC 1817

Query: 1043 GNFDLKTINEMRTPENLELTNPQEFGSSWAAV--------ECPDTLDPRDMCVLNPLREP 1094
            GN D    N+   P      +   +G SW A         EC  +      C  + L + 
Sbjct: 1818 GNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSC---PTCPEDRLEQY 1874

Query: 1095 FAKKECSILLSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQC 1151
                 C  L S     F  CH  V    F+  C+ D   C  GGD +  C ++++Y   C
Sbjct: 1875 EGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDRDILCKALASYVAAC 1932

Query: 1152 CQHGVAV-DWRTPRLCPYDC 1170
               GV + DWR    C   C
Sbjct: 1933 QAAGVVIEDWRAQVGCEITC 1952



 Score =  296 bits (758), Expect = 2e-79
 Identities = 305/1176 (25%), Positives = 449/1176 (38%), Gaps = 199/1176 (16%)

Query: 73   PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS-----FSIQVHNDPQCG 127
            P  ++ C  WG  H  +FDG  +   G  +Y L     P   +     F++   N  + G
Sbjct: 1667 PNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNR-G 1725

Query: 128  SSPYTCSRAVSLFFVGEQ-EIHLAK----EVTHGGMRVQLPHVMGSARLQ--QLAGYVIV 180
            +   +  R V++  +G    IH  +     V   G+   LP  +   R+   Q A   ++
Sbjct: 1726 NPAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALL 1785

Query: 181  RHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHS 240
                   +++D    V + +     G   GLCGN + +P +D V  +G L   +  +  S
Sbjct: 1786 VADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGS 1845

Query: 241  WQEQAPNQPP---GPTTSSLPRPP--CLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPL 295
            W+  AP   P        S P  P   L+Q  G   G      +    PF  CHA+V P 
Sbjct: 1846 WR--APGWDPLCWDECRGSCPTCPEDRLEQYEGP--GFCGPLASGTGGPFTTCHAHVPPE 1901

Query: 296  PFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYN 355
             F   C  D+C   GD    C+ALA Y  AC  AG  ++ WR Q+  C + C E +  Y 
Sbjct: 1902 SFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV-GCEITCPENSH-YE 1959

Query: 356  ECIACCPASC---HPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE-CPCEFHGTLYP 411
             C   CPASC    P  +    E  CV+GC C  G +     CV     C C  +GT + 
Sbjct: 1960 VCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHE 2019

Query: 412  PGSVVKED--CNT-CTC--TSGKWECSTAVC--------------------PAECSVTGD 446
             GS    D  C+  C C    G   C+ A C                     AEC   GD
Sbjct: 2020 AGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGD 2079

Query: 447  IHFTTFDGRRYTFPATCQYILA-----KSRSSGTFTVTLQNAPCGLNQDGACVQSVSVIL 501
             H+ T DG R+ F  TC+Y+L+         +  FTVT+ N   G +Q  +  +SV++ +
Sbjct: 2080 PHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTLQI 2138

Query: 502  HQDPRRQVTLTQAGD-VLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREG 560
            +      +TL+      L  D   +  P+  D+     LS   + V T  G+ + +D + 
Sbjct: 2139 Y---NHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDS 2195

Query: 561  LRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA--CSPLV 618
              + L+V   +     GLCG +N +  DD  +  G P          W+   A  C   V
Sbjct: 2196 F-VRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQGCGECV 2246

Query: 619  SGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDACRC-GQP- 674
            S     PC    Q +     AC V+  T    APC   + P  YF+ C  DAC+  G P 
Sbjct: 2247 SKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPG 2306

Query: 675  CLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACG 734
             LC  +A Y   C+  G  +    R   C L C A   Y  C   C  +C  L++PE C 
Sbjct: 2307 GLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEGC- 2365

Query: 735  VDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCH 794
                       C EGC C  D       D CVP  QC C   G  YP G+   P      
Sbjct: 2366 --------ESACREGCVC--DAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPG----- 2410

Query: 795  CKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGC 854
                   C+ R      P G V                 TC++                 
Sbjct: 2411 -----PECERRCECG--PGGHV-----------------TCQE----------------- 2429

Query: 855  ACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCT 914
                     G AC   EEC            +  +  CH   C R             C 
Sbjct: 2430 ---------GAACGPHEECRL----------EDGVQACHATGCGR-------------CL 2457

Query: 915  AYGDRHYRTFDGLPFDFVGACKVHLVK----STSDVSFSVIVENVNCYSSGMICR----- 965
            A G  HY T DG  +D  G+C   L +       D  FS+++E     ++G + R     
Sbjct: 2458 ANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEK---NAAGDLQRLLVTV 2514

Query: 966  --KFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQR 1023
              + +S+  G  + V  +    P     +    E          +V    + + LL+D  
Sbjct: 2515 AGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGR-------NMVLQTTKGLRLLFDGD 2567

Query: 1024 TTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAA----VECPDT 1079
              + +     ++G+L GLCGNF+    ++   P     ++ + FG++W A      C + 
Sbjct: 2568 AHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEG 2627

Query: 1080 LDPR--DMCVLNPLREPFAKKECSILLSE--VFEICHPVVDVTWFYSNCLTDTCGCSQGG 1135
              P+   +C+        + + C  L +    F  C  V+  + ++  C+ D   C+Q G
Sbjct: 2628 CGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDL--CAQKG 2685

Query: 1136 DCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1170
            D    C S++AY   C   GVAV  WRT   CP  C
Sbjct: 2686 DKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHC 2721



 Score =  280 bits (716), Expect = 1e-74
 Identities = 247/825 (29%), Positives = 336/825 (40%), Gaps = 105/825 (12%)

Query: 60   ATGPRCQMVYNAG---PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQ-- 114
            A G RCQ+V        E  ++CRA G  H  TFDG  Y + G  SYT+V     +    
Sbjct: 450  AAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLP 509

Query: 115  SFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHL---AKEVTHG--------GMRVQLP 163
            +FS++  N+       +  SR VS  +VG   +     +  +T G          R +LP
Sbjct: 510  AFSVEAKNE-------HRGSRRVS--YVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLP 560

Query: 164  HVMGSARLQ--QLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKD 221
              +   RL+  Q     +V       + +D    + + +         GLCGN N DP D
Sbjct: 561  VSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPAD 620

Query: 222  DLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEA-- 279
            D +T  G L  D VEF  SW+    +         L    C    P    G  +  E   
Sbjct: 621  DFLTPDGALAPDAVEFASSWKLDDGDY--------LCEDGCQNNCPACTPGQAQHYEGDR 672

Query: 280  ------LLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 333
                   L  PF  CH  + P PF   C  DLC   G+  + CR L+ YA+AC + G  +
Sbjct: 673  LCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISV 732

Query: 334  QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVD-SEIACVDGCYCPNGLIFED 392
              WR+    C + C   +  Y  C   CP SC+  A+  + S   CV+GC C  G +   
Sbjct: 733  GDWRSP-ANCPLSCPANS-RYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASG 790

Query: 393  GGCVAPAECPCEFHGTLYPPGSVVKED--C-NTCTCTSGKWECS---TAVCPA--ECSV- 443
            G CV  + C C F G    PG  V  D  C   CTC     + +      CPA   CSV 
Sbjct: 791  GACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQ 850

Query: 444  ----------------TGDIHFTTFDGRRYTFPATCQYILAKSRSSG----TFTVTLQNA 483
                            +GD H+ +FDGRR+ F  TC Y+L  S         F V ++N 
Sbjct: 851  NGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENE 910

Query: 484  PCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIP-PYTDDAFEIRRLSSV 542
              G +Q  +  ++V V   +  +  V     G VL+ D  + +P    D   ++ R    
Sbjct: 911  HRG-SQTVSYTRAVRVEA-RGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRD 968

Query: 543  FLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQ 602
             + VRT+ G+ V YD    R+  +V   + E   GLCG FNG+  DD     G   +   
Sbjct: 969  AV-VRTDFGLTVTYDWNA-RVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANAL 1026

Query: 603  LFGNSW--KTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEM--FAPCSAFLSPV 658
             FGNSW  +T   C     G      D  +     S   C +L      F  C + L P 
Sbjct: 1027 AFGNSWQEETRPGCGATEPGD-CPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQ 1085

Query: 659  PYFEQCRRDACRC-GQP-CLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPC 716
                 C  D C   GQ   LC  LA YA  C+  G  V        C LSC     Y  C
Sbjct: 1086 GAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEAC 1145

Query: 717  VAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQ 776
               C  +C DL  P  CG          EC EGC C  D       + C+P   C C  Q
Sbjct: 1146 SYGCPLSCGDLPVPGGCG---------SECHEGCVC--DEGFALSGESCLPLASCGCVHQ 1194

Query: 777  GVDYPPGDSDIPSLG---HCHCKD-GVMSCDSRA--PAAAC-PAG 814
            G  +PPG +  P  G    CHC++ G++SC+S +  P  AC P+G
Sbjct: 1195 GTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSG 1239



 Score =  254 bits (649), Expect = 9e-67
 Identities = 233/821 (28%), Positives = 317/821 (38%), Gaps = 90/821 (10%)

Query: 44   GGECV-HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGS 102
            GG  V  PA C         P  Q  +   P   + C+AWG  H  T DG  +   G   
Sbjct: 2040 GGSLVCTPASCGLGEVCGLLPSGQ--HGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCE 2097

Query: 103  YTLVGR-HEPE--GQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQ---EIHLAKEVTHG 156
            Y L    H P    ++F++ V N+ + GS   + +R+V+L              +++   
Sbjct: 2098 YLLSAPCHGPPLGAENFTVTVANEHR-GSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD 2156

Query: 157  GMRVQLPHVMGSARLQQLAGY-VIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNN 215
            G+ V LP  + S     L+G  V+V   S  +LA+DG S V +++         GLCGN 
Sbjct: 2157 GVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNY 2216

Query: 216  NADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQ--GV 273
            N DP DDL    GK     V       E      P P T      P  Q++ G     GV
Sbjct: 2217 NQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCT------PEQQESFGGPDACGV 2270

Query: 274  YEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 333
                +  L P    CH  V P  +   C  D CQ  G     C A+A Y  AC  AG  L
Sbjct: 2271 ISATDGPLAP----CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQL 2326

Query: 334  QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDG 393
              WR     C + C   +  Y  C   CP SC   ++    E AC +GC C  G +    
Sbjct: 2327 GEWRRP-DFCPLQCPAHSH-YELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGD 2384

Query: 394  GCVAPAECPCEFHGTLYP------PGSVVKEDCNT-------------------CTCTSG 428
             CV   +C C   G  YP      PG   +  C                     C    G
Sbjct: 2385 TCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDG 2444

Query: 429  KWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAK----SRSSGTFTVTLQNAP 484
               C    C   C   G IH+ T DGR Y    +C Y+LA+          F++ L+   
Sbjct: 2445 VQACHATGC-GRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNA 2503

Query: 485  CGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFL 544
             G          +  +L     + V+L Q   V +  +   +P             ++ L
Sbjct: 2504 AG---------DLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVL 2554

Query: 545  RVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLF 604
            +  T  G+R+L+D +   L + +   +     GLCG FNGN  DDF+ P G   S+ + F
Sbjct: 2555 Q--TTKGLRLLFDGDA-HLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETF 2611

Query: 605  GNSWKTLSACSPLVSGSPLDPCDVHL--QAASY-SVQACSVLTGEM--FAPCSAFLSPVP 659
            G +W+   +      G     C V L  + A Y S +AC  L      FA C A LSP  
Sbjct: 2612 GAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSE 2671

Query: 660  YFEQCRRDAC--RCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCV 717
            YF QC  D C  +  +  LC +LA Y   C+  G+ V        C L C A   YS C 
Sbjct: 2672 YFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICT 2731

Query: 718  APCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQG 777
              C  +C  L+    C            C EGC C  D +L +Q  +C+P   C C   G
Sbjct: 2732 RTCQGSCAALSGLTGC---------TTRCFEGCEC-DDRFLLSQG-VCIPVQDCGCTHNG 2780

Query: 778  VDYPPGDSDIPS--LGHCHCKDGVMSCDSRAPAAACPAGQV 816
               P   S + S     C C     S      AA CP G+V
Sbjct: 2781 RYLPVNSSLLTSDCSERCSCSS---SSGLTCQAAGCPPGRV 2818



 Score =  161 bits (408), Expect = 8e-39
 Identities = 154/588 (26%), Positives = 227/588 (38%), Gaps = 47/588 (7%)

Query: 30   RAKCAPSYLFSCFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVET 89
            R +C P    +C  G  C      +CR  +      Q  +  G  R   C A G  H  T
Sbjct: 2416 RCECGPGGHVTCQEGAACGPHE--ECRLEDGV----QACHATGCGR---CLANGGIHYIT 2466

Query: 90   FDGLYYYLSGKGSYTL--VGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEI 147
             DG  Y L G  SY L  V   +P  + FSI +  +               L  V  Q +
Sbjct: 2467 LDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRL-------LVTVAGQVV 2519

Query: 148  HLAK--EVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELL 205
             LA+  +VT  G  V LP  +G  R+      ++++      L +DG + + + +     
Sbjct: 2520 SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFR 2579

Query: 206  GWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQ 265
            G   GLCGN N +  DD V  +G     V  F  +W+    ++  G        P CL +
Sbjct: 2580 GRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAE 2639

Query: 266  NPGTMQGVYEQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYA 323
                 +   E C  L  P  PF  C A +SP  +   C  DLC   GD A  CR+LA Y 
Sbjct: 2640 ETAPYES-NEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYT 2698

Query: 324  RACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCY 383
             AC  AG  ++ WRT    C +HC   +  Y+ C   C  SC   +        C +GC 
Sbjct: 2699 AACQAAGVAVKPWRTD-SFCPLHCPAHSH-YSICTRTCQGSCAALSGLTGCTTRCFEGCE 2756

Query: 384  CPNGLIFEDGGCVAPAECPCEFHGTLYP-PGSVVKEDCN-TCTCTSGK-WECSTAVCP-- 438
            C +  +   G C+   +C C  +G   P   S++  DC+  C+C+S     C  A CP  
Sbjct: 2757 CDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPG 2816

Query: 439  ------AE----------CSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQN 482
                  AE          C ++   + TTFDG R    +   Y L+        T+    
Sbjct: 2817 RVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYR 2876

Query: 483  APCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSV 542
                +       ++V  +        VTLT    V +      +P     +  + R    
Sbjct: 2877 VVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDG 2936

Query: 543  FLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDF 590
             L VR   GV+V     G ++ + V         G CG F+G+  +D+
Sbjct: 2937 SLLVRQKAGVQVWLGANG-KVAVIVSNDHAGKLCGACGNFDGDQTNDW 2983



 Score =  115 bits (287), Expect = 8e-25
 Identities = 111/421 (26%), Positives = 162/421 (38%), Gaps = 61/421 (14%)

Query: 798  GVMSCDSRAPA---AACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGC 854
            G+   D R+PA    +CPA   +  C         +   +C       + S R PC+ GC
Sbjct: 729  GISVGDWRSPANCPLSCPANSRYELCGP-------ACPTSCNGAAAPSNCSGR-PCVEGC 780

Query: 855  ACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSP--C-HTCVCQRGSFQCTLHPCAS 911
             C  G +  G AC     C CT++G +  PG +V +   C   C C   + Q T     S
Sbjct: 781  VCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQS 840

Query: 912  ----------------------TCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD---- 945
                                  TC   GD HY +FDG  FDF+G C   LV S       
Sbjct: 841  CPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL 900

Query: 946  VSFSVIVENVNCYSSGMICRKFISINVGNSLI---------VFDDDSGNPSPESFLDDKQ 996
             +F V+VEN +  S  +   + + +      +         V  DD     P    D   
Sbjct: 901  PAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADG-- 958

Query: 997  EVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTP 1056
            +V  +R G   +V      +T+ +D    V  +    +   L GLCGNF+    +++   
Sbjct: 959  QVQVFRQGRDAVVR-TDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALR 1017

Query: 1057 ENLELTNPQEFGSSWAAVECP--DTLDPRDMCVLNPL--REPFAKKECSILLSE--VFEI 1110
               +  N   FG+SW     P     +P D   L+ L  ++  +K EC IL      F  
Sbjct: 1018 GGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRE 1077

Query: 1111 CHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYD 1169
            CH  +D      +C+ D   C   G     C +++ YA  C   G  V  WR+  LCP  
Sbjct: 1078 CHSKLDPQGAVRDCVYDR--CLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLS 1135

Query: 1170 C 1170
            C
Sbjct: 1136 C 1136



 Score = 98.6 bits (244), Expect = 8e-20
 Identities = 82/297 (27%), Positives = 126/297 (42%), Gaps = 27/297 (9%)

Query: 895  CVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD----VSFSV 950
            C    G   C     A  C A GD HY TFDG  +D +G C   +V+  S+     +FSV
Sbjct: 455  CQVVGGKAGCVAESTA-VCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSV 513

Query: 951  IVENVN------CYSSGMICRKF---ISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTW 1001
              +N +       Y   +  R +   +S+  G    V  D+  +  P S  + +  V+  
Sbjct: 514  EAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQS 573

Query: 1002 RVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLEL 1061
                   + F    +T  WD +  + + A  ++Q Q+ GLCGN++    ++  TP+    
Sbjct: 574  GPRAVVELVFGLV-VTYDWDCQLALSLPA--RFQDQVCGLCGNYNGDPADDFLTPDGALA 630

Query: 1062 TNPQEFGSSWAAVE----CPDTLDPR-DMCVLNPLREPFAKKECSIL--LSEVFEICHPV 1114
             +  EF SSW   +    C D        C     +     + C +L  L   F +CH  
Sbjct: 631  PDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDT 690

Query: 1115 VDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1170
            +D   F   C+ D   C  GG+    C  +SAYA  C + G++V DWR+P  CP  C
Sbjct: 691  LDPRPFLEQCVYDL--CVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSC 745



 Score = 92.4 bits (228), Expect = 6e-18
 Identities = 116/501 (23%), Positives = 186/501 (37%), Gaps = 85/501 (16%)

Query: 1953 SAPALSIVEGLAEALATTTEAN-----TSTTCVPIAEQDCVRHICLEGQLIRVNQSQHC- 2006
            S P+LS  EG   A       +     +  TCVP+ +  C+     +G+   + +  +  
Sbjct: 2355 SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLH----DGRYYPLGEVFYPG 2410

Query: 2007 PQGAAPPRCGILGLAVRVGGDRCCPLWEC-------AC------RCSIFPDLSFVTFDGS 2053
            P+      CG  G      G  C P  EC       AC      RC     + ++T DG 
Sbjct: 2411 PECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGR 2470

Query: 2054 HVALFKEAIYILSQ-----SPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVT 2108
               L     Y+L+Q       DE  ++ +    + +L  L           +  +A QV 
Sbjct: 2471 VYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRL-----------LVTVAGQVV 2519

Query: 2109 IDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTS 2168
                 ++VTVD + V  PV+    R+   G   ++ T   +++ +   + L++   S  S
Sbjct: 2520 SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLM---SIPS 2576

Query: 2169 KAQGH--GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDS 2226
              +G   GLCG  +G+ ++D  L +GS     E    F  +W+ P S    G+       
Sbjct: 2577 PFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVET---FGAAWRAPGSSKGCGE------G 2627

Query: 2227 CATTDCSPCL--RMVSNRTFSACHRFVPPE---SFCELWIRDTKYVQQP----------- 2270
            C    C  CL        +  AC +   P+   + C+  +  ++Y +Q            
Sbjct: 2628 CGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDK 2687

Query: 2271 ---CVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGP 2326
               C +L  Y A C    V ++ WR   +CP  C + S Y  C   C+       G+ G 
Sbjct: 2688 AFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTG- 2746

Query: 2327 LDPEHCQV-LGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCC 2385
                 C     EGC C +  +L +    +CIP   C CT +            S  S  C
Sbjct: 2747 -----CTTRCFEGCECDDRFLLSQ---GVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERC 2798

Query: 2386 QHQCQAPDTIVPVDLGCPSPR 2406
               C +   +     GCP  R
Sbjct: 2799 --SCSSSSGLTCQAAGCPPGR 2817



 Score = 91.3 bits (225), Expect = 1e-17
 Identities = 115/456 (25%), Positives = 171/456 (37%), Gaps = 78/456 (17%)

Query: 1962 GLAEALATTTEANTSTTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLA 2021
            GLA+A+   T A+   T +   E  C    C  GQ                 RC +    
Sbjct: 419  GLAKAIGYATAADCGRTVLSPVEPSCEGMQCAAGQ-----------------RCQV---- 457

Query: 2022 VRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQ--SPDEMLTVHVLD 2079
              VGG   C + E    C    D  + TFDG    +     Y + +  S D+ L    ++
Sbjct: 458  --VGGKAGC-VAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVE 514

Query: 2080 CKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRK-VTVDLQPVWPPVS--RYGFRIED 2136
             K+ + G        LV +     +H V++ R     V VD Q    PVS      R+  
Sbjct: 515  AKNEHRGSRRVSYVGLVTVRA--YSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQ 572

Query: 2137 TGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVG 2196
            +G   ++     + + +     L +   ++    Q  GLCG  +GD A+D    DG++  
Sbjct: 573  SGPRAVVELVFGLVVTYDWDCQLALSLPARFQD-QVCGLCGNYNGDPADDFLTPDGAL-- 629

Query: 2197 GAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCL----------RMVSNRT--- 2243
             A D   F  SW++              D C   +C  C           R+    T   
Sbjct: 630  -APDAVEFASSWKLDDG------DYLCEDGCQN-NCPACTPGQAQHYEGDRLCGMLTKLD 681

Query: 2244 --FSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCI-EWRRSDYC 2296
              F+ CH  + P  F E  + D   V       C  L+ Y   C +  + + +WR    C
Sbjct: 682  GPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANC 741

Query: 2297 PFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHC--QVLGEGCVCSEGTILHRRHSAL 2354
            P  C ++S Y+ C  AC  P +C     G   P +C  +   EGCVC  G +        
Sbjct: 742  PLSCPANSRYELCGPAC--PTSCN----GAAAPSNCSGRPCVEGCVCLPGFV---ASGGA 792

Query: 2355 CIPEAKCACTDSMGVPRALG-ETWNSSLSGCCQHQC 2389
            C+P + C CT   G+  A G E W   L   CQ +C
Sbjct: 793  CVPASSCGCT-FQGLQLAPGQEVWADEL---CQRRC 824



 Score = 90.1 bits (222), Expect = 3e-17
 Identities = 122/510 (23%), Positives = 186/510 (36%), Gaps = 84/510 (16%)

Query: 1992 CLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFD 2051
            C EG L+    S   P  A  P  G LG         C  +    C+ S   D  + TFD
Sbjct: 1216 CQEGGLVSCESSSCGPHEACQPSGGSLG---------CVAVGSSTCQAS--GDPHYTTFD 1264

Query: 2052 GSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDR 2111
            G         +Y+L+Q+      +H       N+   N       ++ +      + +++
Sbjct: 1265 GRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQ 1324

Query: 2112 FNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMI-VEASKTSKA 2170
               KVTV+   +  PV     +I  + H   ++  +D  ++  +     + V        
Sbjct: 1325 RQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQ 1384

Query: 2171 QGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQ--VPSSLTSVGQTRFRP---D 2225
            Q  GLCG  +GD  +D    +GS  G A +   F +SW+  VP S   +  T   P   D
Sbjct: 1385 QMCGLCGNYNGDPKDDFQKPNGSQAGNANE---FGNSWEEVVPDS-PCLPPTPCPPGSED 1440

Query: 2226 SCATTDCSPCLR----------MVSNRT--FSACHRFVPPESFCELWIRDTKY----VQQ 2269
               +  C P L           ++S+ T   S+CH+ V P+   +  I D       +  
Sbjct: 1441 CIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSI 1500

Query: 2270 PCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTAC-------EPPKTCQD 2321
             C  +  YV+ C      +E WR   +CP  C  +S Y+ C   C         P  CQD
Sbjct: 1501 LCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQD 1560

Query: 2322 GILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSL 2381
            G              EGC C  G +    +   C+P  +C C  + GV     E   + L
Sbjct: 1561 G------------CAEGCQCDSGFLY---NGQACVPIQQCGCYHN-GV---YYEPEQTVL 1601

Query: 2382 SGCCQHQ--CQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLC 2439
               C+ Q  C A   +V  +  C   +P    +     L   TKDP             C
Sbjct: 1602 IDNCRQQCTCHAGKGMVCQEHSC---KPGQVCQPSGGILSCVTKDP-------------C 1645

Query: 2440 EGLAPTCRPGHRLLTHFQEDSCCPSYSCEC 2469
             G+  TCRP         +  C P+Y   C
Sbjct: 1646 HGV--TCRPQETCKEQGGQGVCLPNYEATC 1673



 Score = 84.7 bits (208), Expect = 1e-15
 Identities = 105/415 (25%), Positives = 157/415 (37%), Gaps = 79/415 (19%)

Query: 2012 PPRCG---ILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS 2068
            P  CG   + GL +  G   C P+      C  + D  +VT DG          Y+LS  
Sbjct: 2047 PASCGLGEVCGL-LPSGQHGCQPV--STAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAP 2103

Query: 2069 PDEMLTVHVLDCKSANLGHLNWPPFCLVMLN------MTHLAHQVTIDRFNRKVTVDLQP 2122
                       C    LG  N   F + + N             VT+  +N  +T+  + 
Sbjct: 2104 -----------CHGPPLGAEN---FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSAR- 2148

Query: 2123 VWPPVSRYG-------FRIEDTGHMYM------ILTPSDIQIQWLHSSGLMIVEASKTSK 2169
             WP   +         F+++   H ++      + T S + + +   S + +    +   
Sbjct: 2149 -WPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRL----RVPA 2203

Query: 2170 AQGHGLCGICDG---DAANDLTLKDGSV----VGGAEDPAPFLDSWQVPSSLTSVGQTRF 2222
            A    LCG+C     D A+DL    G      VGGA+     + S   PS  T   Q  F
Sbjct: 2204 AYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECV-SKPCPSPCTPEQQESF 2262

Query: 2223 R-PDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVY 2277
              PD+C     +       +   + CH  VPP  + +  + D   VQ      C A+  Y
Sbjct: 2263 GGPDACGVISAT-------DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATY 2315

Query: 2278 VAMCHKFHVCI-EWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQ-VL 2335
            VA C      + EWRR D+CP  C + S Y+ C  +C  P +C         PE C+   
Sbjct: 2316 VAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSC--PVSCP----SLSAPEGCESAC 2369

Query: 2336 GEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQ 2390
             EGCVC  G +L       C+P  +C C    G    LGE +       C+ +C+
Sbjct: 2370 REGCVCDAGFVL---SGDTCVPVGQCGCLHD-GRYYPLGEVFYPGPE--CERRCE 2418



 Score = 78.6 bits (192), Expect = 8e-14
 Identities = 118/489 (24%), Positives = 165/489 (33%), Gaps = 103/489 (21%)

Query: 1983 AEQDCVRHICLEGQLIRVN--QSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCS 2040
            A++ C R     G   +V     Q CP G    RC     +V+ G   C P     C+ S
Sbjct: 816  ADELCQRRCTCNGATHQVTCRDKQSCPAGE---RC-----SVQNGLLGCYPDRFGTCQGS 867

Query: 2041 IFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNM 2100
               D  +V+FDG          Y+L  S  +   +                P   V++  
Sbjct: 868  --GDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL----------------PAFRVLVEN 909

Query: 2101 THLAHQVTIDRFNRKVTVDLQPVWPPVSRY--GFRIEDTGHMYMILTPSDIQIQWLHSSG 2158
             H   Q     + R V V+ + V   V R   G  + D    Y+    +D Q+Q      
Sbjct: 910  EHRGSQTV--SYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGR 967

Query: 2159 LMIVEA---------------SKTSKAQGHGLCGIC---DGDAANDLTLKDGSVVGGAED 2200
              +V                 +K   +    LCG+C   +GD A+DL L+ G   G A +
Sbjct: 968  DAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGG---GQAAN 1024

Query: 2201 PAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRT----------FSACHRF 2250
               F +SWQ     T  G     P  C   D     ++ S             F  CH  
Sbjct: 1025 ALAFGNSWQEE---TRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSK 1081

Query: 2251 VPPESFCELWIRDTKYVQ--------QPCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCS 2301
            + P+      +RD  Y +          C AL  Y A C      +  WR  + CP  C 
Sbjct: 1082 LDPQGA----VRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCP 1137

Query: 2302 SDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKC 2361
              S Y+AC   C  P +C D  +       C    EGCVC EG  L       C+P A C
Sbjct: 1138 PHSHYEACSYGC--PLSCGDLPVPGGCGSECH---EGCVCDEGFAL---SGESCLPLASC 1189

Query: 2362 ACTDSMGVPRALGETW-------------NSSLSGCCQHQCQAPDTIVPV--DLGCPSPR 2406
             C    G     G+T+                L  C    C   +   P    LGC +  
Sbjct: 1190 GCV-HQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVG 1248

Query: 2407 PESCLRFGE 2415
              +C   G+
Sbjct: 1249 SSTCQASGD 1257



 Score = 63.9 bits (154), Expect = 2e-09
 Identities = 113/434 (26%), Positives = 158/434 (36%), Gaps = 67/434 (15%)

Query: 2029 CCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS-----PDEMLTVHVLDCKSA 2083
            C P +E  C   ++ D  + +FDG          Y+L+ +       + LT   +  K+ 
Sbjct: 1665 CLPNYEATCW--LWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQ 1722

Query: 2084 NLGHLNWPPFCLV-MLNMTHLAHQVTIDRFN-RKVTVDLQPVWP--PVSRYGFRIEDTGH 2139
            N G+   P    V ++ +  L   ++I +    KV V +  V    PVS    RI     
Sbjct: 1723 NRGN---PAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQG 1779

Query: 2140 MYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLKDGSVVGG 2197
                L  +D  +Q  +      V+ +  S   G   GLCG  D +  ND    +G++   
Sbjct: 1780 ASKALLVADFGLQVSYDWNWR-VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTL--- 1835

Query: 2198 AEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPC----------------LRMVSN 2241
                AP +  W    S  + G      D C  + C  C                L   + 
Sbjct: 1836 ----APSIPIWG--GSWRAPGWDPLCWDECRGS-CPTCPEDRLEQYEGPGFCGPLASGTG 1888

Query: 2242 RTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCIE-WRRSDYC 2296
              F+ CH  VPPESF +  + D           C AL  YVA C    V IE WR    C
Sbjct: 1889 GPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGC 1948

Query: 2297 PFLCSSDSTYQACVTACEPPKTCQDGILGPL-DPEHCQ-VLGEGCVCSEGTILHRRHSAL 2354
               C  +S Y+ C   C  P +C      PL  P  C+    EGC C  G +L    +  
Sbjct: 1949 EITCPENSHYEVCGPPC--PASCPSP--APLTTPAVCEGPCVEGCQCDAGFVL---SADR 2001

Query: 2355 CIP-EAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRF 2413
            C+P    C C  +     A  E W     G C   C+          G     P SC   
Sbjct: 2002 CVPLNNGCGCWANGTYHEAGSEFW---ADGTCSQWCRCGP-----GGGSLVCTPASC-GL 2052

Query: 2414 GEVALLLPTKDPCC 2427
            GEV  LLP+    C
Sbjct: 2053 GEVCGLLPSGQHGC 2066



 Score = 32.7 bits (73), Expect = 5.3
 Identities = 26/96 (27%), Positives = 33/96 (34%), Gaps = 17/96 (17%)

Query: 811  CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLS--VSARGPCLSGCACPQGLLRHGDACF 868
            CPA   +  C+           RTC+     LS        C  GC C    L     C 
Sbjct: 2721 CPAHSHYSICT-----------RTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCI 2769

Query: 869  LPEECPCTWKGKEYFP--GDQVMSPC-HTCVCQRGS 901
              ++C CT  G+ Y P     + S C   C C   S
Sbjct: 2770 PVQDCGCTHNGR-YLPVNSSLLTSDCSERCSCSSSS 2804


>gi|154146262 Fc fragment of IgG binding protein [Homo sapiens]
          Length = 5405

 Score =  308 bits (790), Expect = 4e-83
 Identities = 310/1218 (25%), Positives = 448/1218 (36%), Gaps = 194/1218 (15%)

Query: 49   HPAFCDCRRFNATGPRCQM---VYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTL 105
            H   C  ++    G RC +   +    P+R   C+  G  H  +FDG  +   G  +Y L
Sbjct: 831  HQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLL 890

Query: 106  VGRHEPEGQ--SFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLP 163
            VG         +F + V N+ + GS   + +RAV    V  + + +A    + G +V + 
Sbjct: 891  VGSCGQNAALPAFRVLVENEHR-GSQTVSYTRAVR---VEARGVKVAVRREYPG-QVLVD 945

Query: 164  HVMGSARLQQLAGYV---------IVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGN 214
             V+     Q   G V         +VR     T+ +D  + V  K+         GLCGN
Sbjct: 946  DVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGN 1005

Query: 215  NNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVY 274
             N DP DDL    G    + + F +SWQE+     PG   +     P L           
Sbjct: 1006 FNGDPADDLALRGGGQAANALAFGNSWQEETR---PGCGATEPGDCPKLDSLVAQQLQSK 1062

Query: 275  EQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRP 332
             +C  L  P  PF  CH+ + P      C  D C   G     C ALA YA AC  AG  
Sbjct: 1063 NECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGAT 1122

Query: 333  LQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFED 392
            +  WR++   C + C   +  Y  C   CP SC            C +GC C  G     
Sbjct: 1123 VHPWRSE-ELCPLSCPPHSH-YEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSG 1180

Query: 393  GGCVAPAECPCEFHGTLYPPGSVVKED--CNT-CTCTSGKW-ECSTAVC----------- 437
              C+  A C C   GT +PPG        C++ C C  G    C ++ C           
Sbjct: 1181 ESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGG 1240

Query: 438  --------PAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSS----GTFTVTLQNAPC 485
                     + C  +GD H+TTFDGRR+ F  TC Y+LA++  +      F V  +N   
Sbjct: 1241 SLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAW 1300

Query: 486  GLNQDGA----CVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS- 540
            G  +        VQ  +  L  + R+        D+ L        P      +IR    
Sbjct: 1301 GNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKL--------PVVLANGQIRASQH 1352

Query: 541  SVFLRVRTNVGVRVLYDREGLRLYLQ--VDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPE 598
               + + T+ G+RV YD   L  Y++  V   + +   GLCG +NG+ +DDF  P G   
Sbjct: 1353 GSDVVIETDFGLRVAYD---LVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQA 1409

Query: 599  STPQLFGNSWKTLSACSPLVSGSPLDP----------CDVHLQAASYSVQACSVLTGEM- 647
                 FGNSW+ +   SP +  +P  P          C   L+      + C +L+    
Sbjct: 1410 GNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTG 1469

Query: 648  -FAPCSAFLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACA 704
              + C   + P    + C  D C  G     LC+ +  Y   C+  G  V+       C 
Sbjct: 1470 PLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCP 1529

Query: 705  LSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADL 764
            + C  +  Y  C   C   C  L++P  C         +D C EGC C      + QA  
Sbjct: 1530 MECPPNSHYELCADTCSLGCSALSAPPQC---------QDGCAEGCQCDSGFLYNGQA-- 1578

Query: 765  CVPRNQCSCHFQGVDYPPGDS----DIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNC 820
            CVP  QC C+  GV Y P  +    +      CH   G M C       +C  GQV    
Sbjct: 1579 CVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKG-MVCQEH----SCKPGQV---- 1629

Query: 821  SDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGK 880
                          C+     LS   + PC            HG  C             
Sbjct: 1630 --------------CQPSGGILSCVTKDPC------------HGVTC------------- 1650

Query: 881  EYFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHL- 939
                      P  TC  Q G   C L    +TC  +GD HY +FDG  FDF G C   L 
Sbjct: 1651 ---------RPQETCKEQGGQGVC-LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLA 1700

Query: 940  ------VKSTSDVSFSVIVENVNCYSSGMICRKFISI-NVGNSLIVFDDDSG-------- 984
                  V +     F+V  +N N  +  +   + +++  +G ++ +  D+ G        
Sbjct: 1701 TTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVL 1760

Query: 985  NPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGN 1044
               P S  D +  V         +  F    + + +D    V V     + G + GLCGN
Sbjct: 1761 TALPVSVADGRISVTQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGN 1817

Query: 1045 FDLKTINEMRTPENLELTNPQEFGSSWAAV--------ECPDTLDPRDMCVLNPLREPFA 1096
             D    N+   P      +   +G SW A         EC  +      C  + L +   
Sbjct: 1818 MDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSC---PTCPEDRLEQYEG 1874

Query: 1097 KKECSILLSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQ 1153
               C  L       F  CH  V    F+  C+ D   C  GGD +  C ++++Y   C  
Sbjct: 1875 PGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDRDILCKALASYVAACQA 1932

Query: 1154 HGVAV-DWRTPRLCPYDC 1170
             GV + DWR    C   C
Sbjct: 1933 AGVVIEDWRAQVGCEITC 1950



 Score =  306 bits (785), Expect = 1e-82
 Identities = 321/1217 (26%), Positives = 449/1217 (36%), Gaps = 193/1217 (15%)

Query: 44   GGECV-HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGS 102
            GG  V  PA C         P  Q  +   P   + C+AWG  H  T DG  +   G   
Sbjct: 3239 GGSLVCTPASCGLGEVCGLLPSGQ--HGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCE 3296

Query: 103  YTLVGR-HEPE--GQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQ---EIHLAKEVTHG 156
            Y L    H P    ++F++ V N+ + GS   + +R+V+L              +++   
Sbjct: 3297 YLLSAPCHGPPLGAENFTVTVANEHR-GSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD 3355

Query: 157  GMRVQLPHVMGSARLQQLAGY-VIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNN 215
            G+ V LP  + S     L+G  V+V   S  +LA+DG S V +++     G   GLCGN 
Sbjct: 3356 GVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNY 3415

Query: 216  NADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQ--GV 273
            N DP DDL    GK     V       E      P P T      P  Q++ G     GV
Sbjct: 3416 NQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCT------PEQQESFGGPDACGV 3469

Query: 274  YEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 333
                +  L P    CH  V P  +   C  D CQ  G     C A+A Y  AC  AG  L
Sbjct: 3470 ISATDGPLAP----CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQL 3525

Query: 334  QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDG 393
            + WR     C   C   +  Y  C   CP SC   ++    E AC +GC C  G +    
Sbjct: 3526 REWRRP-DFCPFQCPAHSH-YELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGD 3583

Query: 394  GCVAPAECPCEFHGTLYPPG---------------------SVVKEDCN---TCTCTSGK 429
             CV   +C C      YP G                     S     C    TC  + G 
Sbjct: 3584 TCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGS 3643

Query: 430  WECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSS----GTFTVTLQNAPC 485
              C  AV    C  +GD H+TTFDG R+ F  TC Y+LA++  +      F V  +N   
Sbjct: 3644 LGC-VAVGSTTCQASGDPHYTTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAW 3702

Query: 486  GLNQDGA----CVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS- 540
            G  +        VQ  +  L  + R+        D+ L        P      +IR    
Sbjct: 3703 GNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKL--------PVVLANGQIRASQH 3754

Query: 541  SVFLRVRTNVGVRVLYDREGLRLYLQ--VDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPE 598
               + + T+ G+RV YD   L  Y++  V   + +   GLCG +NG+ +DDF  P G   
Sbjct: 3755 GSDVVIETDFGLRVAYD---LVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQA 3811

Query: 599  STPQLFGNSWKTLSACSPLV------SGS----PLDPCDVHLQAASYSVQACSVLTGEM- 647
                 FGNSW+ +   SP +       GS    P D C   L+      + C +L+    
Sbjct: 3812 GNANEFGNSWEEVVPDSPCLPPPTCPPGSAGCIPSDKCPPELEKKYQKEEFCGLLSSPTG 3871

Query: 648  -FAPCSAFLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACA 704
              + C   + P    + C  D C  G     LC+ +  Y   C+  G  V+       C 
Sbjct: 3872 PLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRNETFCP 3931

Query: 705  LSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADL 764
            + C  +  Y  C   C   C  L++P  C          D C EGC C      + QA  
Sbjct: 3932 MECPQNSHYELCADTCSLGCSALSAPLQC---------PDGCAEGCQCDSGFLYNGQA-- 3980

Query: 765  CVPRNQCSCHFQGVDYPPGDSDI--PSLGHCHCKDG-VMSCDSRAPAAACPAGQVFVNCS 821
            CVP  QC C+  GV Y P  + +       C C  G V+ C       +C  GQV     
Sbjct: 3981 CVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHVGKVVVCQEH----SCKPGQV----- 4031

Query: 822  DLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKE 881
                         C+     LS   + PC            HG  C              
Sbjct: 4032 -------------CQPSGGILSCVTKDPC------------HGVTC-------------- 4052

Query: 882  YFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHL-- 939
                     P  TC  Q G   C L    +TC  +GD HY +FDG  FDF G C   L  
Sbjct: 4053 --------RPQETCKEQGGQGVC-LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLAT 4103

Query: 940  -----VKSTSDVSFSVIVENVNCYSSGMICRKFISI-NVGNSLIVFDDDSG--------N 985
                 V +     F+V  +N N  +  +   + +++  +G ++ +  D+ G         
Sbjct: 4104 TGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLT 4163

Query: 986  PSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNF 1045
              P S  D +  V         +  F    + + +D    V V     + G + GLCGN 
Sbjct: 4164 ALPVSVADGRISVAQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNM 4220

Query: 1046 DLKTINEMRTPENLELTNPQEFGSSWAAV--------ECPDTLDPRDMCVLNPLREPFAK 1097
            D    N+   P      +   +G SW A         EC  +      C  + L +    
Sbjct: 4221 DRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSC---PTCPEDRLEQYEGP 4277

Query: 1098 KECSILLSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQH 1154
              C  L S     F  CH  V    F+  C+ D   C  GGD +  C ++++Y   C   
Sbjct: 4278 GFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDRDILCKALASYVAACQAA 4335

Query: 1155 GVAV-DWRTPRLCPYDC 1170
            GV + DWR    C   C
Sbjct: 4336 GVVIEDWRAQVGCEITC 4352



 Score =  304 bits (778), Expect = 9e-82
 Identities = 319/1217 (26%), Positives = 448/1217 (36%), Gaps = 193/1217 (15%)

Query: 44   GGECV-HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGS 102
            GG  V  PA C         P  Q  +   P   + C+AWG  H  T DG  +   G   
Sbjct: 2038 GGSLVCTPASCGLGEVCGLLPSGQ--HGCQPVSTAECQAWGDPHYVTLDGHRFNFQGTCE 2095

Query: 103  YTLVGR-HEPE--GQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQ---EIHLAKEVTHG 156
            Y L    H P    ++F++ V N+ + GS   + +R+V+L              +++   
Sbjct: 2096 YLLSAPCHGPPLGAENFTVTVANEHR-GSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD 2154

Query: 157  GMRVQLPHVMGSARLQQLAGY-VIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNN 215
            G+ V LP  + S     L+G  V+V   S  +LA+DG S V +++     G   GLCGN 
Sbjct: 2155 GVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNY 2214

Query: 216  NADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQ--GV 273
            N DP DDL    GK     V       E      P P T      P  Q++ G     GV
Sbjct: 2215 NQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCT------PEQQESFGGPDACGV 2268

Query: 274  YEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 333
                +  L P    CH  V P  +   C  D CQ  G     C A+A Y  AC  AG  L
Sbjct: 2269 ISATDGPLAP----CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQL 2324

Query: 334  QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDG 393
            + WR     C   C   +  Y  C   CP SC   ++    E AC +GC C  G +    
Sbjct: 2325 REWRRP-DFCPFQCPAHSH-YELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGD 2382

Query: 394  GCVAPAECPCEFHGTLYPPG---------------------SVVKEDCN---TCTCTSGK 429
             CV   +C C      YP G                     S     C    TC  + G 
Sbjct: 2383 TCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGS 2442

Query: 430  WECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSS----GTFTVTLQNAPC 485
              C  AV    C  +GD H+TTFDGRR+ F  TC Y+LA++  +      F V  +N   
Sbjct: 2443 LGC-VAVGSTTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAW 2501

Query: 486  GLNQDGA----CVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS- 540
            G  +        VQ  +  L  + R+        D+ L        P      +IR    
Sbjct: 2502 GNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKL--------PVVLANGQIRASQH 2553

Query: 541  SVFLRVRTNVGVRVLYDREGLRLYLQ--VDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPE 598
               + + T+ G+RV YD   L  Y++  V   + +   GLCG +NG+ +DDF  P G   
Sbjct: 2554 GSDVVIETDFGLRVAYD---LVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQA 2610

Query: 599  STPQLFGNSWKTLSACSPLV------SGS----PLDPCDVHLQAASYSVQACSVLTGEM- 647
                 FGNSW+ +   SP +       GS    P + C   L+      + C +L+    
Sbjct: 2611 GNANEFGNSWEEVVPDSPCLPPPTCPPGSEGCIPSEECPPELEKKYQKEEFCGLLSSPTG 2670

Query: 648  -FAPCSAFLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACA 704
              + C   + P    + C  D C  G     LC+ +  Y   C+  G  V+       C 
Sbjct: 2671 PLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGQVEPWRNETFCP 2730

Query: 705  LSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADL 764
            + C  +  Y  C   C   C  L++P  C          D C EGC C      + QA  
Sbjct: 2731 MECPQNSHYELCADTCSLGCSALSAPLQC---------PDGCAEGCQCDSGFLYNGQA-- 2779

Query: 765  CVPRNQCSCHFQGVDYPPGDSDI--PSLGHCHCKDG-VMSCDSRAPAAACPAGQVFVNCS 821
            CVP  QC C+  G  Y P  + +       C C  G V+ C       +C  GQV     
Sbjct: 2780 CVPIQQCGCYHNGAYYEPEQTVLIDNCRQQCTCHVGKVVVCQEH----SCKPGQV----- 2830

Query: 822  DLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKE 881
                         C+     LS   + PC            HG  C              
Sbjct: 2831 -------------CQPSGGILSCVNKDPC------------HGVTC-------------- 2851

Query: 882  YFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHL-- 939
                     P  TC  Q G   C L    +TC  +GD HY +FDG  FDF G C   L  
Sbjct: 2852 --------RPQETCKEQGGQGVC-LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLAT 2902

Query: 940  -----VKSTSDVSFSVIVENVNCYSSGMICRKFISI-NVGNSLIVFDDDSG--------N 985
                 V +     F+V  +N N  +  +   + +++  +G ++ +  D+ G         
Sbjct: 2903 TGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLT 2962

Query: 986  PSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNF 1045
              P S  D +  V         +  F    + + +D    V V     + G + GLCGN 
Sbjct: 2963 ALPVSVADGRISVTQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNM 3019

Query: 1046 DLKTINEMRTPENLELTNPQEFGSSWAAV--------ECPDTLDPRDMCVLNPLREPFAK 1097
            D    N+   P      +   +G SW A         EC  +      C  + L +    
Sbjct: 3020 DRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSC---PTCPEDRLEQYEGP 3076

Query: 1098 KECSILLSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQH 1154
              C  L       F  CH  V    F+  C+ D   C  GGD +  C ++++Y   C   
Sbjct: 3077 GFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDRDILCKALASYVAACQAA 3134

Query: 1155 GVAV-DWRTPRLCPYDC 1170
            GV + DWR    C   C
Sbjct: 3135 GVVIEDWRAQVGCEITC 3151



 Score =  298 bits (762), Expect = 7e-80
 Identities = 305/1174 (25%), Positives = 450/1174 (38%), Gaps = 197/1174 (16%)

Query: 73   PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS-----FSIQVHNDPQCG 127
            P  ++ C  WG  H  +FDG  +   G  +Y L     P   +     F++   N  + G
Sbjct: 4069 PNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNR-G 4127

Query: 128  SSPYTCSRAVSLFFVGEQ-EIHLAK--EVTHGGMRVQLPHVMGSARLQ--QLAGYVIVRH 182
            +   +  R V++  +G    IH  +  +V   G+   LP  +   R+   Q A   ++  
Sbjct: 4128 NPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVA 4187

Query: 183  QSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ 242
                 +++D    V + +     G   GLCGN + +P +D V  +G L   +  +  SW+
Sbjct: 4188 DFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWR 4247

Query: 243  EQAPNQPP---GPTTSSLPRPP--CLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPF 297
              AP   P        S P  P   L+Q  G   G      +    PF  CHA+V P  F
Sbjct: 4248 --APGWDPLCWDECRGSCPTCPEDRLEQYEGP--GFCGPLSSGTGGPFTTCHAHVPPESF 4303

Query: 298  TASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNEC 357
               C  D+C   GD    C+ALA Y  AC  AG  ++ WR Q+  C + C E +  Y  C
Sbjct: 4304 FKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV-GCEITCPENSH-YEVC 4361

Query: 358  IACCPASC---HPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE-CPCEFHGTLYPPG 413
               CPASC    P  +    E  CV+GC C  G +     CV     C C  +GT +  G
Sbjct: 4362 GPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAG 4421

Query: 414  SVVKED--CNT-CTC--TSGKWECSTAVC--------------------PAECSVTGDIH 448
            S    D  C+  C C    G   C+ A C                     AEC   GD H
Sbjct: 4422 SEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPH 4481

Query: 449  FTTFDGRRYTFPATCQYILA-----KSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQ 503
            + T DG R+ F  TC+Y+L+         +  FTVT+ N   G +Q  +  +SV++ ++ 
Sbjct: 4482 YVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTLQIY- 4539

Query: 504  DPRRQVTLTQAGD-VLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLR 562
                 +TL+      L  D   +  P+  D+     LS   + V T  G+ + +D +   
Sbjct: 4540 --NHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSF- 4596

Query: 563  LYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA--CSPLVSG 620
            + L+V   +     GLCG +N +  DD  +  G P          W+   A  C   VS 
Sbjct: 4597 VRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQGCGECVSK 4648

Query: 621  SPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDACRC-GQP-CL 676
                PC    Q +     AC V+  T    APC   + P  YF+ C  DAC+  G P  L
Sbjct: 4649 PCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGL 4708

Query: 677  CATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVD 736
            C  +A Y   C+  G  +    R   C L C A   Y  C   C  +C  L++PE C   
Sbjct: 4709 CPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEGC--- 4765

Query: 737  GGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCHCK 796
                     C EGC C  D       D CVP  QC C   G  YP G+   P        
Sbjct: 4766 ------ESACREGCVC--DAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPG------- 4810

Query: 797  DGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCAC 856
                 C+ R      P G V                 TC++                   
Sbjct: 4811 ---PECERRCECG--PGGHV-----------------TCQE------------------- 4829

Query: 857  PQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAY 916
                   G AC   EEC            +  +  CH   C R             C A 
Sbjct: 4830 -------GAACGPHEECRL----------EDGVQACHATGCGR-------------CLAN 4859

Query: 917  GDRHYRTFDGLPFDFVGACKVHLVK----STSDVSFSVIVENVNCYSSGMICR------- 965
            G  HY T DG  +D  G+C   L +       D  FS+++E     ++G + R       
Sbjct: 4860 GGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEK---NAAGDLQRLLVTVAG 4916

Query: 966  KFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTT 1025
            + +S+  G  + V  +    P     +    E          +V    + + LL+D    
Sbjct: 4917 QVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGR-------NMVLQTTKGLRLLFDGDAH 4969

Query: 1026 VHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAA----VECPDTLD 1081
            + +     ++G+L GLCGNF+    ++   P     ++ + FG++W A      C +   
Sbjct: 4970 LLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCG 5029

Query: 1082 PR--DMCVLNPLREPFAKKECSILLSE--VFEICHPVVDVTWFYSNCLTDTCGCSQGGDC 1137
            P+   +C+        + + C  L +    F  C  V+  + ++  C+ D   C+Q GD 
Sbjct: 5030 PQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDL--CAQKGDK 5087

Query: 1138 ECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1170
               C S++AY   C   GVAV  WRT   CP  C
Sbjct: 5088 AFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHC 5121



 Score =  280 bits (716), Expect = 1e-74
 Identities = 247/825 (29%), Positives = 336/825 (40%), Gaps = 105/825 (12%)

Query: 60   ATGPRCQMVYNAG---PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQ-- 114
            A G RCQ+V        E  ++CRA G  H  TFDG  Y + G  SYT+V     +    
Sbjct: 450  AAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLP 509

Query: 115  SFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHL---AKEVTHG--------GMRVQLP 163
            +FS++  N+       +  SR VS  +VG   +     +  +T G          R +LP
Sbjct: 510  AFSVEAKNE-------HRGSRRVS--YVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLP 560

Query: 164  HVMGSARLQ--QLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKD 221
              +   RL+  Q     +V       + +D    + + +         GLCGN N DP D
Sbjct: 561  VSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPAD 620

Query: 222  DLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEA-- 279
            D +T  G L  D VEF  SW+    +         L    C    P    G  +  E   
Sbjct: 621  DFLTPDGALAPDAVEFASSWKLDDGDY--------LCEDGCQNNCPACTPGQAQHYEGDR 672

Query: 280  ------LLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 333
                   L  PF  CH  + P PF   C  DLC   G+  + CR L+ YA+AC + G  +
Sbjct: 673  LCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISV 732

Query: 334  QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVD-SEIACVDGCYCPNGLIFED 392
              WR+    C + C   +  Y  C   CP SC+  A+  + S   CV+GC C  G +   
Sbjct: 733  GDWRSP-ANCPLSCPANS-RYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASG 790

Query: 393  GGCVAPAECPCEFHGTLYPPGSVVKED--C-NTCTCTSGKWECS---TAVCPA--ECSV- 443
            G CV  + C C F G    PG  V  D  C   CTC     + +      CPA   CSV 
Sbjct: 791  GACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQ 850

Query: 444  ----------------TGDIHFTTFDGRRYTFPATCQYILAKSRSSG----TFTVTLQNA 483
                            +GD H+ +FDGRR+ F  TC Y+L  S         F V ++N 
Sbjct: 851  NGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENE 910

Query: 484  PCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIP-PYTDDAFEIRRLSSV 542
              G +Q  +  ++V V   +  +  V     G VL+ D  + +P    D   ++ R    
Sbjct: 911  HRG-SQTVSYTRAVRVEA-RGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRD 968

Query: 543  FLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQ 602
             + VRT+ G+ V YD    R+  +V   + E   GLCG FNG+  DD     G   +   
Sbjct: 969  AV-VRTDFGLTVTYDWNA-RVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANAL 1026

Query: 603  LFGNSW--KTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEM--FAPCSAFLSPV 658
             FGNSW  +T   C     G      D  +     S   C +L      F  C + L P 
Sbjct: 1027 AFGNSWQEETRPGCGATEPGD-CPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQ 1085

Query: 659  PYFEQCRRDACRC-GQP-CLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPC 716
                 C  D C   GQ   LC  LA YA  C+  G  V        C LSC     Y  C
Sbjct: 1086 GAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEAC 1145

Query: 717  VAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQ 776
               C  +C DL  P  CG          EC EGC C  D       + C+P   C C  Q
Sbjct: 1146 SYGCPLSCGDLPVPGGCG---------SECHEGCVC--DEGFALSGESCLPLASCGCVHQ 1194

Query: 777  GVDYPPGDSDIPSLG---HCHCKD-GVMSCDSRA--PAAAC-PAG 814
            G  +PPG +  P  G    CHC++ G++SC+S +  P  AC P+G
Sbjct: 1195 GTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSG 1239



 Score =  254 bits (649), Expect = 9e-67
 Identities = 233/821 (28%), Positives = 317/821 (38%), Gaps = 90/821 (10%)

Query: 44   GGECV-HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGS 102
            GG  V  PA C         P  Q  +   P   + C+AWG  H  T DG  +   G   
Sbjct: 4440 GGSLVCTPASCGLGEVCGLLPSGQ--HGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCE 4497

Query: 103  YTLVGR-HEPE--GQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQ---EIHLAKEVTHG 156
            Y L    H P    ++F++ V N+ + GS   + +R+V+L              +++   
Sbjct: 4498 YLLSAPCHGPPLGAENFTVTVANEHR-GSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD 4556

Query: 157  GMRVQLPHVMGSARLQQLAGY-VIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNN 215
            G+ V LP  + S     L+G  V+V   S  +LA+DG S V +++         GLCGN 
Sbjct: 4557 GVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNY 4616

Query: 216  NADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQ--GV 273
            N DP DDL    GK     V       E      P P T      P  Q++ G     GV
Sbjct: 4617 NQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCT------PEQQESFGGPDACGV 4670

Query: 274  YEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 333
                +  L P    CH  V P  +   C  D CQ  G     C A+A Y  AC  AG  L
Sbjct: 4671 ISATDGPLAP----CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQL 4726

Query: 334  QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDG 393
              WR     C + C   +  Y  C   CP SC   ++    E AC +GC C  G +    
Sbjct: 4727 GEWRRP-DFCPLQCPAHSH-YELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGD 4784

Query: 394  GCVAPAECPCEFHGTLYP------PGSVVKEDCNT-------------------CTCTSG 428
             CV   +C C   G  YP      PG   +  C                     C    G
Sbjct: 4785 TCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDG 4844

Query: 429  KWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAK----SRSSGTFTVTLQNAP 484
               C    C   C   G IH+ T DGR Y    +C Y+LA+          F++ L+   
Sbjct: 4845 VQACHATGC-GRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNA 4903

Query: 485  CGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFL 544
             G          +  +L     + V+L Q   V +  +   +P             ++ L
Sbjct: 4904 AG---------DLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVL 4954

Query: 545  RVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLF 604
            +  T  G+R+L+D +   L + +   +     GLCG FNGN  DDF+ P G   S+ + F
Sbjct: 4955 Q--TTKGLRLLFDGDA-HLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETF 5011

Query: 605  GNSWKTLSACSPLVSGSPLDPCDVHL--QAASY-SVQACSVLTGEM--FAPCSAFLSPVP 659
            G +W+   +      G     C V L  + A Y S +AC  L      FA C A LSP  
Sbjct: 5012 GAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSE 5071

Query: 660  YFEQCRRDAC--RCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCV 717
            YF QC  D C  +  +  LC +LA Y   C+  G+ V        C L C A   YS C 
Sbjct: 5072 YFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICT 5131

Query: 718  APCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQG 777
              C  +C  L+    C            C EGC C  D +L +Q  +C+P   C C   G
Sbjct: 5132 RTCQGSCAALSGLTGC---------TTRCFEGCEC-DDRFLLSQG-VCIPVQDCGCTHNG 5180

Query: 778  VDYPPGDSDIPS--LGHCHCKDGVMSCDSRAPAAACPAGQV 816
               P   S + S     C C     S      AA CP G+V
Sbjct: 5181 RYLPVNSSLLTSDCSERCSCSS---SSGLTCQAAGCPPGRV 5218



 Score =  248 bits (634), Expect = 5e-65
 Identities = 229/809 (28%), Positives = 327/809 (40%), Gaps = 102/809 (12%)

Query: 73   PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS-----FSIQVHNDPQCG 127
            P  ++ C  WG  H  +FDG  +   G  +Y L     P   +     F++   N  + G
Sbjct: 1667 PNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNR-G 1725

Query: 128  SSPYTCSRAVSLFFVGEQ-EIHLAK--EVTHGGMRVQLPHVMGSARLQ--QLAGYVIVRH 182
            +   +  R V++  +G    IH  +  +V   G+   LP  +   R+   Q A   ++  
Sbjct: 1726 NPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVA 1785

Query: 183  QSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ 242
                 +++D    V + +     G   GLCGN + +P +D V  +G L   +  +  SW+
Sbjct: 1786 DFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWR 1845

Query: 243  EQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEAL-----LRP----PFDACHAYVS 293
              AP   P      L    C    P   +   EQ E       L P    PF  CHA+V 
Sbjct: 1846 --APGWDP------LCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVP 1897

Query: 294  PLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFT 353
            P  F   C  D+C   GD    C+ALA Y  AC  AG  ++ WR Q+  C + C E +  
Sbjct: 1898 PESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV-GCEITCPENSH- 1955

Query: 354  YNECIACCPASC---HPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE-CPCEFHGTL 409
            Y  C + CPASC    P  +    E  CV+GC C  G +     CV     C C  +GT 
Sbjct: 1956 YEVCGSPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTY 2015

Query: 410  YPPGSVVKED--CNT-CTC--TSGKWECSTAVC--------------------PAECSVT 444
            +  GS    D  C+  C C    G   C+ A C                     AEC   
Sbjct: 2016 HEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAW 2075

Query: 445  GDIHFTTFDGRRYTFPATCQYILA-----KSRSSGTFTVTLQNAPCGLNQDGACVQSVSV 499
            GD H+ T DG R+ F  TC+Y+L+         +  FTVT+ N   G +Q  +  +SV++
Sbjct: 2076 GDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTL 2134

Query: 500  ILHQDPRRQVTLTQAGD-VLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDR 558
             ++      +TL+      L  D   +  P+  D+     LS   + V T  G+ + +D 
Sbjct: 2135 QIY---NHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDG 2191

Query: 559  EGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA--CSP 616
            +   + L+V   +     GLCG +N +  DD  +  G P          W+   A  C  
Sbjct: 2192 DSF-VRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQGCGE 2242

Query: 617  LVSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDACRC-GQ 673
             VS     PC    Q +     AC V+  T    APC   + P  YF+ C  DAC+  G 
Sbjct: 2243 CVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGH 2302

Query: 674  P-CLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEA 732
            P  LC  +A Y   C+  G  +    R   C   C A   Y  C   C  +C  L++PE 
Sbjct: 2303 PGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPEG 2362

Query: 733  CGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLG- 791
            C            C EGC C  D       D CVP  QC C      YP G +  P  G 
Sbjct: 2363 C---------ESACREGCVC--DAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGC 2411

Query: 792  --HCHCKD-GVMSCD--SRAPAAAC-PAG 814
               C C++ G +SC+  S  P   C P+G
Sbjct: 2412 DSLCRCREGGEVSCEPSSCGPHETCRPSG 2440



 Score =  248 bits (634), Expect = 5e-65
 Identities = 240/854 (28%), Positives = 339/854 (39%), Gaps = 115/854 (13%)

Query: 33   CAPSY-LFSCFNGGECVHPAFC----DCRRFNATGPRCQMVYNAGPERDSICRAWGQHHV 87
            C PS  + SC N   C H   C     C+     G          P  ++ C  WG  H 
Sbjct: 2831 CQPSGGILSCVNKDPC-HGVTCRPQETCKEQGGQGVCL-------PNYEATCWLWGDPHY 2882

Query: 88   ETFDGLYYYLSGKGSYTLVGRHEPEGQS-----FSIQVHNDPQCGSSPYTCSRAVSLFFV 142
             +FDG  +   G  +Y L     P   +     F++   N  + G+   +  R V++  +
Sbjct: 2883 HSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNR-GNPAVSYVRVVTVAAL 2941

Query: 143  GEQ-EIHLAK--EVTHGGMRVQLPHVMGSARLQ--QLAGYVIVRHQSAFTLAWDGASAVY 197
            G    IH  +  +V   G+   LP  +   R+   Q A   ++       +++D    V 
Sbjct: 2942 GTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVD 3001

Query: 198  IKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSL 257
            + +     G   GLCGN + +P +D V  +G L   +  +  SW+  AP   P      L
Sbjct: 3002 VTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWR--APGWDP------L 3053

Query: 258  PRPPCLQQNPGTMQGVYEQCEAL-----LRP----PFDACHAYVSPLPFTASCTSDLCQS 308
                C    P   +   EQ E       L P    PF  CHA+V P  F   C  D+C  
Sbjct: 3054 CWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMG 3113

Query: 309  MGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASC--- 365
             GD    C+ALA Y  AC  AG  ++ WR Q+  C + C E +  Y  C   CPASC   
Sbjct: 3114 GGDRDILCKALASYVAACQAAGVVIEDWRAQV-GCEITCPENSH-YEVCGPPCPASCPSP 3171

Query: 366  HPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE-CPCEFHGTLYPPGSVVKED--CNT 422
             P  +    E  CV+GC C  G +     CV     C C  +GT +  GS    D  C+ 
Sbjct: 3172 APLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQ 3231

Query: 423  -CTC--TSGKWECSTAVC--------------------PAECSVTGDIHFTTFDGRRYTF 459
             C C    G   C+ A C                     AEC   GD H+ T DG R+ F
Sbjct: 3232 WCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDF 3291

Query: 460  PATCQYILA-----KSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQA 514
              TC+Y+L+         +  FTVT+ N   G +Q  +  +SV++ ++      +TL+  
Sbjct: 3292 QGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTLQIY---NHSLTLSAR 3347

Query: 515  GD-VLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVE 573
                L  D   +  P+  D+     LS   + V T  G+ + +D +   + L+V   +  
Sbjct: 3348 WPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSF-VRLRVPAAYAG 3406

Query: 574  DTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA--CSPLVSGSPLDPCDVHLQ 631
               GLCG +N +  DD  +  G P          W+   A  C   VS     PC    Q
Sbjct: 3407 SLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQGCGECVSKPCPSPCTPEQQ 3458

Query: 632  AASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDACRC-GQP-CLCATLAHYAHLC 687
             +     AC V+  T    APC   + P  YF+ C  DAC+  G P  LC  +A Y   C
Sbjct: 3459 ESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAAC 3518

Query: 688  RRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECV 747
            +  G  +    R   C   C A   Y  C   C  +C  L++PE C            C 
Sbjct: 3519 QAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPEGC---------ESACR 3569

Query: 748  EGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLG---HCHCKD-GVMSCD 803
            EGC C  D       D CVP  QC C      YP G +  P  G    C C++ G +SC+
Sbjct: 3570 EGCVC--DAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCE 3627

Query: 804  --SRAPAAAC-PAG 814
              S  P   C P+G
Sbjct: 3628 PSSCGPHETCRPSG 3641



 Score =  161 bits (408), Expect = 8e-39
 Identities = 154/588 (26%), Positives = 227/588 (38%), Gaps = 47/588 (7%)

Query: 30   RAKCAPSYLFSCFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVET 89
            R +C P    +C  G  C      +CR  +      Q  +  G  R   C A G  H  T
Sbjct: 4816 RCECGPGGHVTCQEGAACGPHE--ECRLEDGV----QACHATGCGR---CLANGGIHYIT 4866

Query: 90   FDGLYYYLSGKGSYTL--VGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEI 147
             DG  Y L G  SY L  V   +P  + FSI +  +               L  V  Q +
Sbjct: 4867 LDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRL-------LVTVAGQVV 4919

Query: 148  HLAK--EVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELL 205
             LA+  +VT  G  V LP  +G  R+      ++++      L +DG + + + +     
Sbjct: 4920 SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFR 4979

Query: 206  GWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQ 265
            G   GLCGN N +  DD V  +G     V  F  +W+    ++  G        P CL +
Sbjct: 4980 GRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAE 5039

Query: 266  NPGTMQGVYEQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYA 323
                 +   E C  L  P  PF  C A +SP  +   C  DLC   GD A  CR+LA Y 
Sbjct: 5040 ETAPYES-NEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYT 5098

Query: 324  RACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCY 383
             AC  AG  ++ WRT    C +HC   +  Y+ C   C  SC   +        C +GC 
Sbjct: 5099 AACQAAGVAVKPWRTD-SFCPLHCPAHSH-YSICTRTCQGSCAALSGLTGCTTRCFEGCE 5156

Query: 384  CPNGLIFEDGGCVAPAECPCEFHGTLYP-PGSVVKEDCN-TCTCTSGK-WECSTAVCP-- 438
            C +  +   G C+   +C C  +G   P   S++  DC+  C+C+S     C  A CP  
Sbjct: 5157 CDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPG 5216

Query: 439  ------AE----------CSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQN 482
                  AE          C ++   + TTFDG R    +   Y L+        T+    
Sbjct: 5217 RVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYR 5276

Query: 483  APCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSV 542
                +       ++V  +        VTLT    V +      +P     +  + R    
Sbjct: 5277 VVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDG 5336

Query: 543  FLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDF 590
             L VR   GV+V     G ++ + V         G CG F+G+  +D+
Sbjct: 5337 SLLVRQKAGVQVWLGANG-KVAVIVSNDHAGKLCGACGNFDGDQTNDW 5383



 Score =  115 bits (287), Expect = 8e-25
 Identities = 111/421 (26%), Positives = 162/421 (38%), Gaps = 61/421 (14%)

Query: 798  GVMSCDSRAPA---AACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGC 854
            G+   D R+PA    +CPA   +  C         +   +C       + S R PC+ GC
Sbjct: 729  GISVGDWRSPANCPLSCPANSRYELCGP-------ACPTSCNGAAAPSNCSGR-PCVEGC 780

Query: 855  ACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSP--C-HTCVCQRGSFQCTLHPCAS 911
             C  G +  G AC     C CT++G +  PG +V +   C   C C   + Q T     S
Sbjct: 781  VCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQS 840

Query: 912  ----------------------TCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD---- 945
                                  TC   GD HY +FDG  FDF+G C   LV S       
Sbjct: 841  CPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL 900

Query: 946  VSFSVIVENVNCYSSGMICRKFISINVGNSLI---------VFDDDSGNPSPESFLDDKQ 996
             +F V+VEN +  S  +   + + +      +         V  DD     P    D   
Sbjct: 901  PAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADG-- 958

Query: 997  EVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTP 1056
            +V  +R G   +V      +T+ +D    V  +    +   L GLCGNF+    +++   
Sbjct: 959  QVQVFRQGRDAVVR-TDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALR 1017

Query: 1057 ENLELTNPQEFGSSWAAVECP--DTLDPRDMCVLNPL--REPFAKKECSILLSE--VFEI 1110
               +  N   FG+SW     P     +P D   L+ L  ++  +K EC IL      F  
Sbjct: 1018 GGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRE 1077

Query: 1111 CHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYD 1169
            CH  +D      +C+ D   C   G     C +++ YA  C   G  V  WR+  LCP  
Sbjct: 1078 CHSKLDPQGAVRDCVYDR--CLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLS 1135

Query: 1170 C 1170
            C
Sbjct: 1136 C 1136



 Score = 98.6 bits (244), Expect = 8e-20
 Identities = 82/297 (27%), Positives = 126/297 (42%), Gaps = 27/297 (9%)

Query: 895  CVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD----VSFSV 950
            C    G   C     A  C A GD HY TFDG  +D +G C   +V+  S+     +FSV
Sbjct: 455  CQVVGGKAGCVAESTA-VCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSV 513

Query: 951  IVENVN------CYSSGMICRKF---ISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTW 1001
              +N +       Y   +  R +   +S+  G    V  D+  +  P S  + +  V+  
Sbjct: 514  EAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQS 573

Query: 1002 RVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLEL 1061
                   + F    +T  WD +  + + A  ++Q Q+ GLCGN++    ++  TP+    
Sbjct: 574  GPRAVVELVFGLV-VTYDWDCQLALSLPA--RFQDQVCGLCGNYNGDPADDFLTPDGALA 630

Query: 1062 TNPQEFGSSWAAVE----CPDTLDPR-DMCVLNPLREPFAKKECSIL--LSEVFEICHPV 1114
             +  EF SSW   +    C D        C     +     + C +L  L   F +CH  
Sbjct: 631  PDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDT 690

Query: 1115 VDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1170
            +D   F   C+ D   C  GG+    C  +SAYA  C + G++V DWR+P  CP  C
Sbjct: 691  LDPRPFLEQCVYDL--CVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSC 745



 Score = 92.4 bits (228), Expect = 6e-18
 Identities = 116/501 (23%), Positives = 186/501 (37%), Gaps = 85/501 (16%)

Query: 1953 SAPALSIVEGLAEALATTTEAN-----TSTTCVPIAEQDCVRHICLEGQLIRVNQSQHC- 2006
            S P+LS  EG   A       +     +  TCVP+ +  C+     +G+   + +  +  
Sbjct: 4755 SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLH----DGRYYPLGEVFYPG 4810

Query: 2007 PQGAAPPRCGILGLAVRVGGDRCCPLWEC-------AC------RCSIFPDLSFVTFDGS 2053
            P+      CG  G      G  C P  EC       AC      RC     + ++T DG 
Sbjct: 4811 PECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGR 4870

Query: 2054 HVALFKEAIYILSQ-----SPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVT 2108
               L     Y+L+Q       DE  ++ +    + +L  L           +  +A QV 
Sbjct: 4871 VYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRL-----------LVTVAGQVV 4919

Query: 2109 IDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTS 2168
                 ++VTVD + V  PV+    R+   G   ++ T   +++ +   + L++   S  S
Sbjct: 4920 SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLM---SIPS 4976

Query: 2169 KAQGH--GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDS 2226
              +G   GLCG  +G+ ++D  L +GS     E    F  +W+ P S    G+       
Sbjct: 4977 PFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVET---FGAAWRAPGSSKGCGE------G 5027

Query: 2227 CATTDCSPCL--RMVSNRTFSACHRFVPPE---SFCELWIRDTKYVQQP----------- 2270
            C    C  CL        +  AC +   P+   + C+  +  ++Y +Q            
Sbjct: 5028 CGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDK 5087

Query: 2271 ---CVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGP 2326
               C +L  Y A C    V ++ WR   +CP  C + S Y  C   C+       G+ G 
Sbjct: 5088 AFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTG- 5146

Query: 2327 LDPEHCQV-LGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCC 2385
                 C     EGC C +  +L +    +CIP   C CT +            S  S  C
Sbjct: 5147 -----CTTRCFEGCECDDRFLLSQ---GVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERC 5198

Query: 2386 QHQCQAPDTIVPVDLGCPSPR 2406
               C +   +     GCP  R
Sbjct: 5199 --SCSSSSGLTCQAAGCPPGR 5217



 Score = 91.3 bits (225), Expect = 1e-17
 Identities = 115/456 (25%), Positives = 171/456 (37%), Gaps = 78/456 (17%)

Query: 1962 GLAEALATTTEANTSTTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLA 2021
            GLA+A+   T A+   T +   E  C    C  GQ                 RC +    
Sbjct: 419  GLAKAIGYATAADCGRTVLSPVEPSCEGMQCAAGQ-----------------RCQV---- 457

Query: 2022 VRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQ--SPDEMLTVHVLD 2079
              VGG   C + E    C    D  + TFDG    +     Y + +  S D+ L    ++
Sbjct: 458  --VGGKAGC-VAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVE 514

Query: 2080 CKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRK-VTVDLQPVWPPVS--RYGFRIED 2136
             K+ + G        LV +     +H V++ R     V VD Q    PVS      R+  
Sbjct: 515  AKNEHRGSRRVSYVGLVTVRA--YSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQ 572

Query: 2137 TGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVG 2196
            +G   ++     + + +     L +   ++    Q  GLCG  +GD A+D    DG++  
Sbjct: 573  SGPRAVVELVFGLVVTYDWDCQLALSLPARFQD-QVCGLCGNYNGDPADDFLTPDGAL-- 629

Query: 2197 GAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCL----------RMVSNRT--- 2243
             A D   F  SW++              D C   +C  C           R+    T   
Sbjct: 630  -APDAVEFASSWKLDDG------DYLCEDGCQN-NCPACTPGQAQHYEGDRLCGMLTKLD 681

Query: 2244 --FSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCI-EWRRSDYC 2296
              F+ CH  + P  F E  + D   V       C  L+ Y   C +  + + +WR    C
Sbjct: 682  GPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANC 741

Query: 2297 PFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHC--QVLGEGCVCSEGTILHRRHSAL 2354
            P  C ++S Y+ C  AC  P +C     G   P +C  +   EGCVC  G +        
Sbjct: 742  PLSCPANSRYELCGPAC--PTSCN----GAAAPSNCSGRPCVEGCVCLPGFV---ASGGA 792

Query: 2355 CIPEAKCACTDSMGVPRALG-ETWNSSLSGCCQHQC 2389
            C+P + C CT   G+  A G E W   L   CQ +C
Sbjct: 793  CVPASSCGCT-FQGLQLAPGQEVWADEL---CQRRC 824



 Score = 90.1 bits (222), Expect = 3e-17
 Identities = 122/510 (23%), Positives = 186/510 (36%), Gaps = 84/510 (16%)

Query: 1992 CLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFD 2051
            C EG L+    S   P  A  P  G LG         C  +    C+ S   D  + TFD
Sbjct: 1216 CQEGGLVSCESSSCGPHEACQPSGGSLG---------CVAVGSSTCQAS--GDPHYTTFD 1264

Query: 2052 GSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDR 2111
            G         +Y+L+Q+      +H       N+   N       ++ +      + +++
Sbjct: 1265 GRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQ 1324

Query: 2112 FNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMI-VEASKTSKA 2170
               KVTV+   +  PV     +I  + H   ++  +D  ++  +     + V        
Sbjct: 1325 RQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQ 1384

Query: 2171 QGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQ--VPSSLTSVGQTRFRP---D 2225
            Q  GLCG  +GD  +D    +GS  G A +   F +SW+  VP S   +  T   P   D
Sbjct: 1385 QMCGLCGNYNGDPKDDFQKPNGSQAGNANE---FGNSWEEVVPDS-PCLPPTPCPPGSED 1440

Query: 2226 SCATTDCSPCLR----------MVSNRT--FSACHRFVPPESFCELWIRDTKY----VQQ 2269
               +  C P L           ++S+ T   S+CH+ V P+   +  I D       +  
Sbjct: 1441 CIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSI 1500

Query: 2270 PCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTAC-------EPPKTCQD 2321
             C  +  YV+ C      +E WR   +CP  C  +S Y+ C   C         P  CQD
Sbjct: 1501 LCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQD 1560

Query: 2322 GILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSL 2381
            G              EGC C  G +    +   C+P  +C C  + GV     E   + L
Sbjct: 1561 G------------CAEGCQCDSGFLY---NGQACVPIQQCGCYHN-GV---YYEPEQTVL 1601

Query: 2382 SGCCQHQ--CQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLC 2439
               C+ Q  C A   +V  +  C   +P    +     L   TKDP             C
Sbjct: 1602 IDNCRQQCTCHAGKGMVCQEHSC---KPGQVCQPSGGILSCVTKDP-------------C 1645

Query: 2440 EGLAPTCRPGHRLLTHFQEDSCCPSYSCEC 2469
             G+  TCRP         +  C P+Y   C
Sbjct: 1646 HGV--TCRPQETCKEQGGQGVCLPNYEATC 1673



 Score = 86.3 bits (212), Expect = 4e-16
 Identities = 87/371 (23%), Positives = 133/371 (35%), Gaps = 62/371 (16%)

Query: 848  GPCLSGCACPQGLLRHGDACF-LPEECPCTWKGKEY------FPGDQVMSPCHTCVCQRG 900
            GPC+ GC C  G +   D C  L   C C W    Y      F  D   S    C    G
Sbjct: 3182 GPCVEGCQCDAGFVLSADRCVPLNNGCGC-WANGTYHEAGSEFWADGTCSQWCRCGPGGG 3240

Query: 901  SFQCTLHPCA--------------------STCTAYGDRHYRTFDGLPFDFVGACKVHLV 940
            S  CT   C                     + C A+GD HY T DG  FDF G C+  L 
Sbjct: 3241 SLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLS 3300

Query: 941  -----KSTSDVSFSVIVENVNCYSSGMICRKFISINVGNSLIVFDD--------DSGNPS 987
                       +F+V V N +  S  +   + +++ + N  +            D    +
Sbjct: 3301 APCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVT 3360

Query: 988  PESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDL 1047
                LD     H   +    +V      ++L +D  + V ++    + G L GLCGN++ 
Sbjct: 3361 LPFQLDSLLHAH---LSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQ 3417

Query: 1048 KTINEMRT----PENLELTNPQEFGSSWAAVECPDTLDPRDMCVLNPLREPFAKKECSIL 1103
               ++++     P   ++   Q  G    +  CP    P         +E F   +   +
Sbjct: 3418 DPADDLKAVGGKPAGWQVGGAQGCGEC-VSKPCPSPCTPEQ-------QESFGGPDACGV 3469

Query: 1104 LSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-D 1159
            +S        CH +V    ++  CL D C     G     C +V+ Y   C   G  + +
Sbjct: 3470 ISATDGPLAPCHGLVPPAQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLRE 3527

Query: 1160 WRTPRLCPYDC 1170
            WR P  CP+ C
Sbjct: 3528 WRRPDFCPFQC 3538



 Score = 85.9 bits (211), Expect = 5e-16
 Identities = 100/388 (25%), Positives = 148/388 (38%), Gaps = 76/388 (19%)

Query: 2012 PPRCG---ILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS 2068
            P  CG   + GL +  G   C P+      C  + D  +VT DG          Y+LS  
Sbjct: 2045 PASCGLGEVCGL-LPSGQHGCQPV--STAECQAWGDPHYVTLDGHRFNFQGTCEYLLSAP 2101

Query: 2069 PDEMLTVHVLDCKSANLGHLNWPPFCLVMLN------MTHLAHQVTIDRFNRKVTVDLQP 2122
                       C    LG  N   F + + N             VT+  +N  +T+  + 
Sbjct: 2102 -----------CHGPPLGAEN---FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSAR- 2146

Query: 2123 VWPPVSRYG-------FRIEDTGHMYM------ILTPSDIQIQWLHSSGLMIVEASKTSK 2169
             WP   +         F+++   H ++      + T S + + +   S + +    +   
Sbjct: 2147 -WPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRL----RVPA 2201

Query: 2170 AQGHGLCGICDG---DAANDLTLKDGSV----VGGAEDPAPFLDSWQVPSSLTSVGQTRF 2222
            A    LCG+C     D A+DL    G      VGGA+     + S   PS  T   Q  F
Sbjct: 2202 AYAGSLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECV-SKPCPSPCTPEQQESF 2260

Query: 2223 R-PDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVY 2277
              PD+C     +       +   + CH  VPP  + +  + D   VQ      C A+  Y
Sbjct: 2261 GGPDACGVISAT-------DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATY 2313

Query: 2278 VAMCHKFHVCI-EWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQ-VL 2335
            VA C      + EWRR D+CPF C + S Y+ C  +C  P +C         PE C+   
Sbjct: 2314 VAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSC--PGSCP----SLSAPEGCESAC 2367

Query: 2336 GEGCVCSEGTILHRRHSALCIPEAKCAC 2363
             EGCVC  G +L       C+P  +C C
Sbjct: 2368 REGCVCDAGFVL---SGDTCVPVGQCGC 2392



 Score = 85.9 bits (211), Expect = 5e-16
 Identities = 100/388 (25%), Positives = 148/388 (38%), Gaps = 76/388 (19%)

Query: 2012 PPRCG---ILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS 2068
            P  CG   + GL +  G   C P+      C  + D  +VT DG          Y+LS  
Sbjct: 3246 PASCGLGEVCGL-LPSGQHGCQPV--STAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAP 3302

Query: 2069 PDEMLTVHVLDCKSANLGHLNWPPFCLVMLN------MTHLAHQVTIDRFNRKVTVDLQP 2122
                       C    LG  N   F + + N             VT+  +N  +T+  + 
Sbjct: 3303 -----------CHGPPLGAEN---FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSAR- 3347

Query: 2123 VWPPVSRYG-------FRIEDTGHMYM------ILTPSDIQIQWLHSSGLMIVEASKTSK 2169
             WP   +         F+++   H ++      + T S + + +   S + +    +   
Sbjct: 3348 -WPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRL----RVPA 3402

Query: 2170 AQGHGLCGICDG---DAANDLTLKDGSV----VGGAEDPAPFLDSWQVPSSLTSVGQTRF 2222
            A    LCG+C     D A+DL    G      VGGA+     + S   PS  T   Q  F
Sbjct: 3403 AYAGSLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECV-SKPCPSPCTPEQQESF 3461

Query: 2223 R-PDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVY 2277
              PD+C     +       +   + CH  VPP  + +  + D   VQ      C A+  Y
Sbjct: 3462 GGPDACGVISAT-------DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATY 3514

Query: 2278 VAMCHKFHVCI-EWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQ-VL 2335
            VA C      + EWRR D+CPF C + S Y+ C  +C  P +C         PE C+   
Sbjct: 3515 VAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSC--PGSCP----SLSAPEGCESAC 3568

Query: 2336 GEGCVCSEGTILHRRHSALCIPEAKCAC 2363
             EGCVC  G +L       C+P  +C C
Sbjct: 3569 REGCVCDAGFVL---SGDTCVPVGQCGC 3593



 Score = 84.7 bits (208), Expect = 1e-15
 Identities = 105/415 (25%), Positives = 157/415 (37%), Gaps = 79/415 (19%)

Query: 2012 PPRCG---ILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS 2068
            P  CG   + GL +  G   C P+      C  + D  +VT DG          Y+LS  
Sbjct: 4447 PASCGLGEVCGL-LPSGQHGCQPV--STAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAP 4503

Query: 2069 PDEMLTVHVLDCKSANLGHLNWPPFCLVMLN------MTHLAHQVTIDRFNRKVTVDLQP 2122
                       C    LG  N   F + + N             VT+  +N  +T+  + 
Sbjct: 4504 -----------CHGPPLGAEN---FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSAR- 4548

Query: 2123 VWPPVSRYG-------FRIEDTGHMYM------ILTPSDIQIQWLHSSGLMIVEASKTSK 2169
             WP   +         F+++   H ++      + T S + + +   S + +    +   
Sbjct: 4549 -WPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRL----RVPA 4603

Query: 2170 AQGHGLCGICDG---DAANDLTLKDGSV----VGGAEDPAPFLDSWQVPSSLTSVGQTRF 2222
            A    LCG+C     D A+DL    G      VGGA+     + S   PS  T   Q  F
Sbjct: 4604 AYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECV-SKPCPSPCTPEQQESF 4662

Query: 2223 R-PDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVY 2277
              PD+C     +       +   + CH  VPP  + +  + D   VQ      C A+  Y
Sbjct: 4663 GGPDACGVISAT-------DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATY 4715

Query: 2278 VAMCHKFHVCI-EWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQ-VL 2335
            VA C      + EWRR D+CP  C + S Y+ C  +C  P +C         PE C+   
Sbjct: 4716 VAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSC--PVSCP----SLSAPEGCESAC 4769

Query: 2336 GEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQ 2390
             EGCVC  G +L       C+P  +C C    G    LGE +       C+ +C+
Sbjct: 4770 REGCVCDAGFVL---SGDTCVPVGQCGCLHD-GRYYPLGEVFYPGPE--CERRCE 4818



 Score = 84.3 bits (207), Expect = 2e-15
 Identities = 86/371 (23%), Positives = 133/371 (35%), Gaps = 62/371 (16%)

Query: 848  GPCLSGCACPQGLLRHGDACF-LPEECPCTWKGKEY------FPGDQVMSPCHTCVCQRG 900
            GPC+ GC C  G +   D C  L   C C W    Y      F  D   S    C    G
Sbjct: 1981 GPCVEGCQCDAGFVLSADRCVPLNNGCGC-WANGTYHEAGSEFWADGTCSQWCRCGPGGG 2039

Query: 901  SFQCTLHPCA--------------------STCTAYGDRHYRTFDGLPFDFVGACKVHLV 940
            S  CT   C                     + C A+GD HY T DG  F+F G C+  L 
Sbjct: 2040 SLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFNFQGTCEYLLS 2099

Query: 941  -----KSTSDVSFSVIVENVNCYSSGMICRKFISINVGNSLIVFDD--------DSGNPS 987
                       +F+V V N +  S  +   + +++ + N  +            D    +
Sbjct: 2100 APCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVT 2159

Query: 988  PESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDL 1047
                LD     H   +    +V      ++L +D  + V ++    + G L GLCGN++ 
Sbjct: 2160 LPFQLDSLLHAH---LSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQ 2216

Query: 1048 KTINEMRT----PENLELTNPQEFGSSWAAVECPDTLDPRDMCVLNPLREPFAKKECSIL 1103
               ++++     P   ++   Q  G    +  CP    P         +E F   +   +
Sbjct: 2217 DPADDLKAVGGKPAGWQVGGAQGCGEC-VSKPCPSPCTPEQ-------QESFGGPDACGV 2268

Query: 1104 LSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-D 1159
            +S        CH +V    ++  CL D C     G     C +V+ Y   C   G  + +
Sbjct: 2269 ISATDGPLAPCHGLVPPAQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLRE 2326

Query: 1160 WRTPRLCPYDC 1170
            WR P  CP+ C
Sbjct: 2327 WRRPDFCPFQC 2337



 Score = 83.6 bits (205), Expect = 3e-15
 Identities = 131/574 (22%), Positives = 200/574 (34%), Gaps = 109/574 (18%)

Query: 1953 SAPALSIVEGLAEALATTTEAN-----TSTTCVPIAEQDCVRHI---------------- 1991
            S P+LS  EG   A       +     +  TCVP+ +  C+                   
Sbjct: 3554 SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCD 3613

Query: 1992 ----CLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSF 2047
                C EG  +    S   P     P  G LG         C  +    C+ S   D  +
Sbjct: 3614 SLCRCREGGEVSCEPSSCGPHETCRPSGGSLG---------CVAVGSTTCQAS--GDPHY 3662

Query: 2048 VTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQV 2107
             TFDG         +Y+L+Q+      +H       N+   N       ++ +      +
Sbjct: 3663 TTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTL 3722

Query: 2108 TIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMI-VEASK 2166
             +++   KVTV+   +  PV     +I  + H   ++  +D  ++  +     + V    
Sbjct: 3723 RLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPG 3782

Query: 2167 TSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQ--VPSSLTSVGQTRFRP 2224
                   GLCG  +GD  +D    +GS  G A +   F +SW+  VP S      T   P
Sbjct: 3783 NYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANE---FGNSWEEVVPDSPCLPPPT-CPP 3838

Query: 2225 DS--CATTD-CSPCLR----------MVSNRT--FSACHRFVPPESFCELWIRDTKY--- 2266
             S  C  +D C P L           ++S+ T   S+CH+ V P+   +  I D      
Sbjct: 3839 GSAGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGG 3898

Query: 2267 -VQQPCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTAC-------EPPK 2317
             +   C  +  YV+ C      +E WR   +CP  C  +S Y+ C   C         P 
Sbjct: 3899 NLSILCSNIHAYVSACQAAGGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPL 3958

Query: 2318 TCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETW 2377
             C DG              EGC C  G +    +   C+P  +C C  + GV     E  
Sbjct: 3959 QCPDG------------CAEGCQCDSGFLY---NGQACVPIQQCGCYHN-GV---YYEPE 3999

Query: 2378 NSSLSGCCQHQ--CQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCN 2435
             + L   C+ Q  C     +V  +  C   +P    +     L   TKDP          
Sbjct: 4000 QTVLIDNCRQQCTCHVGKVVVCQEHSC---KPGQVCQPSGGILSCVTKDP---------- 4046

Query: 2436 QTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCEC 2469
               C G+  TCRP         +  C P+Y   C
Sbjct: 4047 ---CHGV--TCRPQETCKEQGGQGVCLPNYEATC 4075



 Score = 82.0 bits (201), Expect = 8e-15
 Identities = 126/579 (21%), Positives = 197/579 (34%), Gaps = 119/579 (20%)

Query: 1953 SAPALSIVEGLAEALATTTEAN-----TSTTCVPIAEQDCVRHI---------------- 1991
            S P+LS  EG   A       +     +  TCVP+ +  C+                   
Sbjct: 2353 SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCD 2412

Query: 1992 ----CLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSF 2047
                C EG  +    S   P     P  G LG         C  +    C+ S   D  +
Sbjct: 2413 SLCRCREGGEVSCEPSSCGPHETCRPSGGSLG---------CVAVGSTTCQAS--GDPHY 2461

Query: 2048 VTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQV 2107
             TFDG         +Y+L+Q+      +H       N+   N       ++ +      +
Sbjct: 2462 TTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTL 2521

Query: 2108 TIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMI-VEASK 2166
             +++   KVTV+   +  PV     +I  + H   ++  +D  ++  +     + V    
Sbjct: 2522 RLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPG 2581

Query: 2167 TSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQ--VPSSLTSVGQTRFRP 2224
                   GLCG  +GD  +D    +GS  G A +   F +SW+  VP S          P
Sbjct: 2582 NYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANE---FGNSWEEVVPDSPC------LPP 2632

Query: 2225 DSCA--------TTDCSPCLR----------MVSNRT--FSACHRFVPPESFCELWIRDT 2264
             +C         + +C P L           ++S+ T   S+CH+ V P+   +  I D 
Sbjct: 2633 PTCPPGSEGCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDL 2692

Query: 2265 KY----VQQPCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTAC------ 2313
                  +   C  +  YV+ C      +E WR   +CP  C  +S Y+ C   C      
Sbjct: 2693 CLGGGNLSILCSNIHAYVSACQAAGGQVEPWRNETFCPMECPQNSHYELCADTCSLGCSA 2752

Query: 2314 -EPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRA 2372
               P  C DG              EGC C  G +    +   C+P  +C C  +     A
Sbjct: 2753 LSAPLQCPDG------------CAEGCQCDSGFLY---NGQACVPIQQCGCYHN----GA 2793

Query: 2373 LGETWNSSLSGCCQHQ--CQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGT 2430
              E   + L   C+ Q  C     +V  +  C   +P    +     L    KDP     
Sbjct: 2794 YYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSC---KPGQVCQPSGGILSCVNKDP----- 2845

Query: 2431 VCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCEC 2469
                    C G+  TCRP         +  C P+Y   C
Sbjct: 2846 --------CHGV--TCRPQETCKEQGGQGVCLPNYEATC 2874



 Score = 78.6 bits (192), Expect = 8e-14
 Identities = 118/489 (24%), Positives = 165/489 (33%), Gaps = 103/489 (21%)

Query: 1983 AEQDCVRHICLEGQLIRVN--QSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCS 2040
            A++ C R     G   +V     Q CP G    RC     +V+ G   C P     C+ S
Sbjct: 816  ADELCQRRCTCNGATHQVTCRDKQSCPAGE---RC-----SVQNGLLGCYPDRFGTCQGS 867

Query: 2041 IFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNM 2100
               D  +V+FDG          Y+L  S  +   +                P   V++  
Sbjct: 868  --GDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL----------------PAFRVLVEN 909

Query: 2101 THLAHQVTIDRFNRKVTVDLQPVWPPVSRY--GFRIEDTGHMYMILTPSDIQIQWLHSSG 2158
             H   Q     + R V V+ + V   V R   G  + D    Y+    +D Q+Q      
Sbjct: 910  EHRGSQTV--SYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGR 967

Query: 2159 LMIVEA---------------SKTSKAQGHGLCGIC---DGDAANDLTLKDGSVVGGAED 2200
              +V                 +K   +    LCG+C   +GD A+DL L+ G   G A +
Sbjct: 968  DAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGG---GQAAN 1024

Query: 2201 PAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRT----------FSACHRF 2250
               F +SWQ     T  G     P  C   D     ++ S             F  CH  
Sbjct: 1025 ALAFGNSWQEE---TRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSK 1081

Query: 2251 VPPESFCELWIRDTKYVQ--------QPCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCS 2301
            + P+      +RD  Y +          C AL  Y A C      +  WR  + CP  C 
Sbjct: 1082 LDPQGA----VRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCP 1137

Query: 2302 SDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKC 2361
              S Y+AC   C  P +C D  +       C    EGCVC EG  L       C+P A C
Sbjct: 1138 PHSHYEACSYGC--PLSCGDLPVPGGCGSECH---EGCVCDEGFAL---SGESCLPLASC 1189

Query: 2362 ACTDSMGVPRALGETW-------------NSSLSGCCQHQCQAPDTIVPV--DLGCPSPR 2406
             C    G     G+T+                L  C    C   +   P    LGC +  
Sbjct: 1190 GCV-HQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVG 1248

Query: 2407 PESCLRFGE 2415
              +C   G+
Sbjct: 1249 SSTCQASGD 1257



 Score = 67.0 bits (162), Expect = 3e-10
 Identities = 113/432 (26%), Positives = 159/432 (36%), Gaps = 65/432 (15%)

Query: 2029 CCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS-----PDEMLTVHVLDCKSA 2083
            C P +E  C   ++ D  + +FDG          Y+L+ +       + LT   +  K+ 
Sbjct: 1665 CLPNYEATCW--LWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQ 1722

Query: 2084 NLGHLNWPPFCLV-MLNMTHLAHQVTIDRFN-RKVTVDLQPVWPPVSRYGFRIEDTGHMY 2141
            N G+   P    V ++ +  L   ++I +    KV V+      PVS    RI  T    
Sbjct: 1723 NRGN---PAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGAS 1779

Query: 2142 MILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLKDGSVVGGAE 2199
              L  +D  +Q  +      V+ +  S   G   GLCG  D +  ND    +G++     
Sbjct: 1780 KALLVADFGLQVSYDWNWR-VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTL----- 1833

Query: 2200 DPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPC----------------LRMVSNRT 2243
              AP +  W    S  + G      D C  + C  C                L   +   
Sbjct: 1834 --APSIPIWG--GSWRAPGWDPLCWDECRGS-CPTCPEDRLEQYEGPGFCGPLAPGTGGP 1888

Query: 2244 FSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCIE-WRRSDYCPF 2298
            F+ CH  VPPESF +  + D           C AL  YVA C    V IE WR    C  
Sbjct: 1889 FTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEI 1948

Query: 2299 LCSSDSTYQACVTACEPPKTCQDGILGPL-DPEHCQ-VLGEGCVCSEGTILHRRHSALCI 2356
             C  +S Y+ C + C  P +C      PL  P  C+    EGC C  G +L    +  C+
Sbjct: 1949 TCPENSHYEVCGSPC--PASCPSP--APLTTPAVCEGPCVEGCQCDAGFVL---SADRCV 2001

Query: 2357 P-EAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGE 2415
            P    C C  +     A  E W     G C   C+          G     P SC   GE
Sbjct: 2002 PLNNGCGCWANGTYHEAGSEFW---ADGTCSQWCRCGP-----GGGSLVCTPASC-GLGE 2052

Query: 2416 VALLLPTKDPCC 2427
            V  LLP+    C
Sbjct: 2053 VCGLLPSGQHGC 2064



 Score = 67.0 bits (162), Expect = 3e-10
 Identities = 126/501 (25%), Positives = 178/501 (35%), Gaps = 85/501 (16%)

Query: 1977 TTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGIL---------GLAVRV--- 2024
            T  +    Q C  H+   G+++   +    P     P  GIL         G+  R    
Sbjct: 2800 TVLIDNCRQQCTCHV---GKVVVCQEHSCKPGQVCQPSGGILSCVNKDPCHGVTCRPQET 2856

Query: 2025 -----GGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS-----PDEMLT 2074
                 G   C P +E  C   ++ D  + +FDG          Y+L+ +       + LT
Sbjct: 2857 CKEQGGQGVCLPNYEATCW--LWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLT 2914

Query: 2075 VHVLDCKSANLGHLNWPPFCLV-MLNMTHLAHQVTIDRFN-RKVTVDLQPVWPPVSRYGF 2132
               +  K+ N G+   P    V ++ +  L   ++I +    KV V+      PVS    
Sbjct: 2915 PFTVTTKNQNRGN---PAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADG 2971

Query: 2133 RIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLK 2190
            RI  T      L  +D  +Q  +      V+ +  S   G   GLCG  D +  ND    
Sbjct: 2972 RISVTQGASKALLVADFGLQVSYDWNWR-VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFP 3030

Query: 2191 DGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPC--------------- 2235
            +G++       AP +  W    S  + G      D C  + C  C               
Sbjct: 3031 NGTL-------APSIPIWG--GSWRAPGWDPLCWDECRGS-CPTCPEDRLEQYEGPGFCG 3080

Query: 2236 -LRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCIE- 2289
             L   +   F+ CH  VPPESF +  + D           C AL  YVA C    V IE 
Sbjct: 3081 PLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIED 3140

Query: 2290 WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPL-DPEHCQ-VLGEGCVCSEGTIL 2347
            WR    C   C  +S Y+ C   C  P +C      PL  P  C+    EGC C  G +L
Sbjct: 3141 WRAQVGCEITCPENSHYEVCGPPC--PASCPSP--APLTTPAVCEGPCVEGCQCDAGFVL 3196

Query: 2348 HRRHSALCIP-EAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPR 2406
                +  C+P    C C  +     A  E W     G C   C+          G     
Sbjct: 3197 ---SADRCVPLNNGCGCWANGTYHEAGSEFW---ADGTCSQWCRCGP-----GGGSLVCT 3245

Query: 2407 PESCLRFGEVALLLPTKDPCC 2427
            P SC   GEV  LLP+    C
Sbjct: 3246 PASC-GLGEVCGLLPSGQHGC 3265



 Score = 65.9 bits (159), Expect = 6e-10
 Identities = 123/499 (24%), Positives = 174/499 (34%), Gaps = 81/499 (16%)

Query: 1977 TTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVR--VGGDRCCPLWE 2034
            T  +    Q C  H+   G+++   +    P     P  GIL    +    G  C P   
Sbjct: 4001 TVLIDNCRQQCTCHV---GKVVVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQET 4057

Query: 2035 CA-------------CRCSIFPDLSFVTFDGSHVALFKEAIYILSQS-----PDEMLTVH 2076
            C                C ++ D  + +FDG          Y+L+ +       + LT  
Sbjct: 4058 CKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPF 4117

Query: 2077 VLDCKSANLGHLNWPPFCLV-MLNMTHLAHQVTIDRFN-RKVTVDLQPVWPPVSRYGFRI 2134
             +  K+ N G+   P    V ++ +  L   ++I +    KV V+      PVS    RI
Sbjct: 4118 TVTTKNQNRGN---PAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRI 4174

Query: 2135 EDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLKDG 2192
                     L  +D  +Q  +      V+ +  S   G   GLCG  D +  ND    +G
Sbjct: 4175 SVAQGASKALLVADFGLQVSYDWNWR-VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNG 4233

Query: 2193 SVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPC----------------L 2236
            ++       AP +  W    S  + G      D C  + C  C                L
Sbjct: 4234 TL-------APSIPIWG--GSWRAPGWDPLCWDECRGS-CPTCPEDRLEQYEGPGFCGPL 4283

Query: 2237 RMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCIE-WR 2291
               +   F+ CH  VPPESF +  + D           C AL  YVA C    V IE WR
Sbjct: 4284 SSGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWR 4343

Query: 2292 RSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPL-DPEHCQ-VLGEGCVCSEGTILHR 2349
                C   C  +S Y+ C   C  P +C      PL  P  C+    EGC C  G +L  
Sbjct: 4344 AQVGCEITCPENSHYEVCGPPC--PASCPSP--APLTTPAVCEGPCVEGCQCDAGFVL-- 4397

Query: 2350 RHSALCIP-EAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPE 2408
              +  C+P    C C  +     A  E W     G C   C+          G     P 
Sbjct: 4398 -SADRCVPLNNGCGCWANGTYHEAGSEFW---ADGTCSQWCRCGP-----GGGSLVCTPA 4448

Query: 2409 SCLRFGEVALLLPTKDPCC 2427
            SC   GEV  LLP+    C
Sbjct: 4449 SC-GLGEVCGLLPSGQHGC 4466



 Score = 32.7 bits (73), Expect = 5.3
 Identities = 26/96 (27%), Positives = 33/96 (34%), Gaps = 17/96 (17%)

Query: 811  CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLS--VSARGPCLSGCACPQGLLRHGDACF 868
            CPA   +  C+           RTC+     LS        C  GC C    L     C 
Sbjct: 5121 CPAHSHYSICT-----------RTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCI 5169

Query: 869  LPEECPCTWKGKEYFP--GDQVMSPC-HTCVCQRGS 901
              ++C CT  G+ Y P     + S C   C C   S
Sbjct: 5170 PVQDCGCTHNGR-YLPVNSSLLTSDCSERCSCSSSS 5204


>gi|239757282 PREDICTED: similar to Fc fragment of IgG binding protein
            [Homo sapiens]
          Length = 1403

 Score =  297 bits (761), Expect = 9e-80
 Identities = 305/1178 (25%), Positives = 452/1178 (38%), Gaps = 205/1178 (17%)

Query: 73   PERDSICRAWGQHHVETFDGLYYYLSGKGSYTL-----VGRHEPEGQSFSIQVHNDPQCG 127
            P  ++ C  WG  H  +FDG  +   G  +Y L     +G        F++   N+ + G
Sbjct: 69   PNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLTPFTVTTKNENR-G 127

Query: 128  SSPYTCSRAVSLFFVGEQ-EIHLAK--EVTHGGMRVQLPHVMGSARLQ--QLAGYVIVRH 182
            +   +  R V++  +G    IH  +  +V   G+   LP  +   R+   Q A   ++  
Sbjct: 128  NPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVA 187

Query: 183  QSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ 242
                 +++D    V + +     G   GLCGN + +P +D V  +G L   +  +  SW+
Sbjct: 188  DFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWR 247

Query: 243  EQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEAL-----LRP----PFDACHAYVS 293
              AP   P      L    C    P   +   EQ E       L P    PF  CHA+V 
Sbjct: 248  --APGWDP------LCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVP 299

Query: 294  PLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFT 353
            P  F   C  D+C   GD    C+ALA Y  AC  AG  ++ WR Q+  C + C E +  
Sbjct: 300  PESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVVIEDWRAQV-GCEITCPENSH- 357

Query: 354  YNECIACCPASC---HPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE-CPCEFHGTL 409
            Y  C   CPASC    P  +    E  CV+GC C  G +     CV     C C  +GT 
Sbjct: 358  YEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTY 417

Query: 410  YPPGSVVKED--CNT-CTC--TSGKWECSTAVC--------------------PAECSVT 444
            +  GS    D  C+  C C    G   C+ A C                     AEC   
Sbjct: 418  HEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAW 477

Query: 445  GDIHFTTFDGRRYTFPATCQYILA-----KSRSSGTFTVTLQNAPCGLNQDGACVQSVSV 499
            GD H+ T DG R+ F  TC+Y+L+         +  FTVT+ N   G +Q  +  +SV++
Sbjct: 478  GDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTL 536

Query: 500  ILHQDPRRQVTLTQAGD-VLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDR 558
             ++      +TL+      L  D   +  P+  D+     LS   + V T  G+ + +D 
Sbjct: 537  QIY---NHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDG 593

Query: 559  EGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA--CSP 616
            +   + L+V   +     GLCG +N +  DD  +  G P          W+   A  C  
Sbjct: 594  DSF-VRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQGCGE 644

Query: 617  LVSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDACRC-GQ 673
             VS     PC    Q +     AC V+  T    APC   + P  YF+ C  DAC+  G 
Sbjct: 645  CVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGH 704

Query: 674  P-CLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEA 732
            P  LC  +A Y   C+  G  +    R   C L C A   Y  C   C  +C  L++PE 
Sbjct: 705  PGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEG 764

Query: 733  CGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGH 792
            C            C EGC C  D       D CVP  QC C   G  YP G+   P    
Sbjct: 765  C---------ESACREGCVC--DAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPG--- 810

Query: 793  CHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLS 852
                     C+ R      P G V                 TC++               
Sbjct: 811  -------PECERRCECG--PGGHV-----------------TCQE--------------- 829

Query: 853  GCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPCAST 912
                       G AC   EEC            +  +  CH   C R             
Sbjct: 830  -----------GAACGPHEECRL----------EDGVQACHATGCGR------------- 855

Query: 913  CTAYGDRHYRTFDGLPFDFVGACKVHLVK----STSDVSFSVIVENVNCYSSGMICR--- 965
            C A G  HY T DG  +D  G+C   L +       D  FS+++E     ++G + R   
Sbjct: 856  CLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEK---NAAGDLQRLLV 912

Query: 966  ----KFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWD 1021
                + +S+  G  + V  +    P     +    E          +V    + + LL+D
Sbjct: 913  TVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGR-------NMVLQTTKGLRLLFD 965

Query: 1022 QRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSW----AAVECP 1077
                + +     ++G+L GLCGNF+    ++   P     ++ + FG++W    ++  C 
Sbjct: 966  GDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCG 1025

Query: 1078 DTLDPR--DMCVLNPLREPFAKKECSILLSE--VFEICHPVVDVTWFYSNCLTDTCGCSQ 1133
            +   P+   +C+        + + C  L +    F  C  V+  + ++  C+ D   C+Q
Sbjct: 1026 EGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDL--CAQ 1083

Query: 1134 GGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1170
             GD    C S++AY   C   GVAV  WRT   CP  C
Sbjct: 1084 KGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHC 1121



 Score =  254 bits (649), Expect = 9e-67
 Identities = 233/821 (28%), Positives = 317/821 (38%), Gaps = 90/821 (10%)

Query: 44   GGECV-HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGS 102
            GG  V  PA C         P  Q  +   P   + C+AWG  H  T DG  +   G   
Sbjct: 440  GGSLVCTPASCGLGEVCGLLPSGQ--HGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCE 497

Query: 103  YTLVGR-HEPE--GQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQ---EIHLAKEVTHG 156
            Y L    H P    ++F++ V N+ + GS   + +R+V+L              +++   
Sbjct: 498  YLLSAPCHGPPLGAENFTVTVANEHR-GSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD 556

Query: 157  GMRVQLPHVMGSARLQQLAGY-VIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNN 215
            G+ V LP  + S     L+G  V+V   S  +LA+DG S V +++         GLCGN 
Sbjct: 557  GVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNY 616

Query: 216  NADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQ--GV 273
            N DP DDL    GK     V       E      P P T      P  Q++ G     GV
Sbjct: 617  NQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCT------PEQQESFGGPDACGV 670

Query: 274  YEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 333
                +  L P    CH  V P  +   C  D CQ  G     C A+A Y  AC  AG  L
Sbjct: 671  ISATDGPLAP----CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQL 726

Query: 334  QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDG 393
              WR     C + C   +  Y  C   CP SC   ++    E AC +GC C  G +    
Sbjct: 727  GEWRRP-DFCPLQCPAHSH-YELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGD 784

Query: 394  GCVAPAECPCEFHGTLYP------PGSVVKEDCNT-------------------CTCTSG 428
             CV   +C C   G  YP      PG   +  C                     C    G
Sbjct: 785  TCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDG 844

Query: 429  KWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAK----SRSSGTFTVTLQNAP 484
               C    C   C   G IH+ T DGR Y    +C Y+LA+          F++ L+   
Sbjct: 845  VQACHATGC-GRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNA 903

Query: 485  CGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFL 544
             G          +  +L     + V+L Q   V +  +   +P             ++ L
Sbjct: 904  AG---------DLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVL 954

Query: 545  RVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLF 604
            +  T  G+R+L+D +   L + +   +     GLCG FNGN  DDF+ P G   S+ + F
Sbjct: 955  Q--TTKGLRLLFDGDA-HLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETF 1011

Query: 605  GNSWKTLSACSPLVSGSPLDPCDVHL--QAASY-SVQACSVLTGEM--FAPCSAFLSPVP 659
            G +W+   +      G     C V L  + A Y S +AC  L      FA C A LSP  
Sbjct: 1012 GAAWRVPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSE 1071

Query: 660  YFEQCRRDAC--RCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCV 717
            YF QC  D C  +  +  LC +LA Y   C+  G+ V        C L C A   YS C 
Sbjct: 1072 YFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICT 1131

Query: 718  APCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQG 777
              C  +C  L+    C            C EGC C  D +L +Q  +C+P   C C   G
Sbjct: 1132 RTCQGSCAALSGLTGC---------TTRCFEGCEC-DDRFLLSQG-VCIPVQDCGCTHNG 1180

Query: 778  VDYPPGDSDIPS--LGHCHCKDGVMSCDSRAPAAACPAGQV 816
               P   S + S     C C     S      AA CP G+V
Sbjct: 1181 RYLPVNSSLLTSDCSERCSCSS---SSGLTCQAAGCPPGRV 1218



 Score =  161 bits (407), Expect = 1e-38
 Identities = 154/588 (26%), Positives = 227/588 (38%), Gaps = 47/588 (7%)

Query: 30   RAKCAPSYLFSCFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVET 89
            R +C P    +C  G  C      +CR  +      Q  +  G  R   C A G  H  T
Sbjct: 816  RCECGPGGHVTCQEGAACGPHE--ECRLEDGV----QACHATGCGR---CLANGGIHYIT 866

Query: 90   FDGLYYYLSGKGSYTL--VGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEI 147
             DG  Y L G  SY L  V   +P  + FSI +  +               L  V  Q +
Sbjct: 867  LDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRL-------LVTVAGQVV 919

Query: 148  HLAK--EVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELL 205
             LA+  +VT  G  V LP  +G  R+      ++++      L +DG + + + +     
Sbjct: 920  SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFR 979

Query: 206  GWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQ 265
            G   GLCGN N +  DD V  +G     V  F  +W+    ++  G        P CL +
Sbjct: 980  GRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEGCGPQGCPVCLAE 1039

Query: 266  NPGTMQGVYEQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYA 323
                 +   E C  L  P  PF  C A +SP  +   C  DLC   GD A  CR+LA Y 
Sbjct: 1040 ETAPYES-NEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYT 1098

Query: 324  RACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCY 383
             AC  AG  ++ WRT    C +HC   +  Y+ C   C  SC   +        C +GC 
Sbjct: 1099 AACQAAGVAVKPWRTD-SFCPLHCPAHSH-YSICTRTCQGSCAALSGLTGCTTRCFEGCE 1156

Query: 384  CPNGLIFEDGGCVAPAECPCEFHGTLYP-PGSVVKEDCN-TCTCTSGK-WECSTAVCP-- 438
            C +  +   G C+   +C C  +G   P   S++  DC+  C+C+S     C  A CP  
Sbjct: 1157 CDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPG 1216

Query: 439  ------AE----------CSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQN 482
                  AE          C ++   + TTFDG R    +   Y L+        T+    
Sbjct: 1217 RVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYR 1276

Query: 483  APCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSV 542
                +       ++V  +        VTLT    V +      +P     +  + R    
Sbjct: 1277 VVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDG 1336

Query: 543  FLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDF 590
             L VR   GV+V     G ++ + V         G CG F+G+  +D+
Sbjct: 1337 SLLVRQKAGVQVWLGANG-KVAVIVSNDHAGKLCGACGNFDGDQTNDW 1383



 Score = 94.0 bits (232), Expect = 2e-18
 Identities = 117/501 (23%), Positives = 187/501 (37%), Gaps = 85/501 (16%)

Query: 1953 SAPALSIVEGLAEALATTTEAN-----TSTTCVPIAEQDCVRHICLEGQLIRVNQSQHC- 2006
            S P+LS  EG   A       +     +  TCVP+ +  C+     +G+   + +  +  
Sbjct: 755  SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLH----DGRYYPLGEVFYPG 810

Query: 2007 PQGAAPPRCGILGLAVRVGGDRCCPLWEC-------AC------RCSIFPDLSFVTFDGS 2053
            P+      CG  G      G  C P  EC       AC      RC     + ++T DG 
Sbjct: 811  PECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGR 870

Query: 2054 HVALFKEAIYILSQ-----SPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVT 2108
               L     Y+L+Q       DE  ++ +    + +L  L           +  +A QV 
Sbjct: 871  VYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRL-----------LVTVAGQVV 919

Query: 2109 IDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTS 2168
                 ++VTVD + V  PV+    R+   G   ++ T   +++ +   + L++   S  S
Sbjct: 920  SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLM---SIPS 976

Query: 2169 KAQGH--GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDS 2226
              +G   GLCG  +G+ ++D  L +GS     E    F  +W+VP S    G+       
Sbjct: 977  PFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVET---FGAAWRVPGSSKGCGE------G 1027

Query: 2227 CATTDCSPCL--RMVSNRTFSACHRFVPPE---SFCELWIRDTKYVQQP----------- 2270
            C    C  CL        +  AC +   P+   + C+  +  ++Y +Q            
Sbjct: 1028 CGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDK 1087

Query: 2271 ---CVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGP 2326
               C +L  Y A C    V ++ WR   +CP  C + S Y  C   C+       G+ G 
Sbjct: 1088 AFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTG- 1146

Query: 2327 LDPEHCQV-LGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCC 2385
                 C     EGC C +  +L +    +CIP   C CT +            S  S  C
Sbjct: 1147 -----CTTRCFEGCECDDRFLLSQ---GVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERC 1198

Query: 2386 QHQCQAPDTIVPVDLGCPSPR 2406
               C +   +     GCP  R
Sbjct: 1199 --SCSSSSGLTCQAAGCPPGR 1217



 Score = 84.7 bits (208), Expect = 1e-15
 Identities = 105/415 (25%), Positives = 157/415 (37%), Gaps = 79/415 (19%)

Query: 2012 PPRCG---ILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS 2068
            P  CG   + GL +  G   C P+      C  + D  +VT DG          Y+LS  
Sbjct: 447  PASCGLGEVCGL-LPSGQHGCQPV--STAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAP 503

Query: 2069 PDEMLTVHVLDCKSANLGHLNWPPFCLVMLN------MTHLAHQVTIDRFNRKVTVDLQP 2122
                       C    LG  N   F + + N             VT+  +N  +T+  + 
Sbjct: 504  -----------CHGPPLGAEN---FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSAR- 548

Query: 2123 VWPPVSRYG-------FRIEDTGHMYM------ILTPSDIQIQWLHSSGLMIVEASKTSK 2169
             WP   +         F+++   H ++      + T S + + +   S + +    +   
Sbjct: 549  -WPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRL----RVPA 603

Query: 2170 AQGHGLCGICDG---DAANDLTLKDGSV----VGGAEDPAPFLDSWQVPSSLTSVGQTRF 2222
            A    LCG+C     D A+DL    G      VGGA+     + S   PS  T   Q  F
Sbjct: 604  AYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECV-SKPCPSPCTPEQQESF 662

Query: 2223 R-PDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVY 2277
              PD+C     +       +   + CH  VPP  + +  + D   VQ      C A+  Y
Sbjct: 663  GGPDACGVISAT-------DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATY 715

Query: 2278 VAMCHKFHVCI-EWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQ-VL 2335
            VA C      + EWRR D+CP  C + S Y+ C  +C  P +C         PE C+   
Sbjct: 716  VAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSC--PVSCP----SLSAPEGCESAC 769

Query: 2336 GEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQ 2390
             EGCVC  G +L       C+P  +C C    G    LGE +       C+ +C+
Sbjct: 770  REGCVCDAGFVL---SGDTCVPVGQCGCLHD-GRYYPLGEVFYPGPE--CERRCE 818



 Score = 80.9 bits (198), Expect = 2e-14
 Identities = 77/315 (24%), Positives = 117/315 (37%), Gaps = 43/315 (13%)

Query: 891  PCHTCVC-------QRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHL---- 939
            PCH   C       ++G     L    +TC  +GD HY +FDG  FDF G C   L    
Sbjct: 46   PCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTG 105

Query: 940  ---VKSTSDVSFSVIVENVNCYSSGMICRKFISI-NVGNSLIVFDDDSG--------NPS 987
               V +     F+V  +N N  +  +   + +++  +G ++ +  D+ G           
Sbjct: 106  CLGVSTQGLTPFTVTTKNENRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTAL 165

Query: 988  PESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDL 1047
            P S  D +  V         +  F    + + +D    V V     + G + GLCGN D 
Sbjct: 166  PVSVADGRISVAQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDR 222

Query: 1048 KTINEMRTPENLELTNPQEFGSSWAAV--------ECPDTLDPRDMCVLNPLREPFAKKE 1099
               N+   P      +   +G SW A         EC  +      C  + L +      
Sbjct: 223  NPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSC---PTCPEDRLEQYEGPGF 279

Query: 1100 CSILLSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGV 1156
            C  L       F  CH  V    F+  C+ D   C  GGD +  C ++++Y   C   GV
Sbjct: 280  CGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDHDILCKALASYVAACQAAGV 337

Query: 1157 AV-DWRTPRLCPYDC 1170
             + DWR    C   C
Sbjct: 338  VIEDWRAQVGCEITC 352



 Score = 64.3 bits (155), Expect = 2e-09
 Identities = 112/432 (25%), Positives = 157/432 (36%), Gaps = 65/432 (15%)

Query: 2029 CCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS-----PDEMLTVHVLDCKSA 2083
            C P +E  C   ++ D  + +FDG          Y+L+ +       + LT   +  K+ 
Sbjct: 67   CLPNYEATCW--LWGDPHYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLTPFTVTTKNE 124

Query: 2084 NLGHLNWPPFCLV-MLNMTHLAHQVTIDRFN-RKVTVDLQPVWPPVSRYGFRIEDTGHMY 2141
            N G+   P    V ++ +  L   ++I +    KV V+      PVS    RI       
Sbjct: 125  NRGN---PAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGAS 181

Query: 2142 MILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLKDGSVVGGAE 2199
              L  +D  +Q  +      V+ +  S   G   GLCG  D +  ND    +G++     
Sbjct: 182  KALLVADFGLQVSYDWNWR-VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTL----- 235

Query: 2200 DPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPC----------------LRMVSNRT 2243
              AP +  W    S  + G      D C  + C  C                L   +   
Sbjct: 236  --APSIPIWG--GSWRAPGWDPLCWDECRGS-CPTCPEDRLEQYEGPGFCGPLAPGTGGP 290

Query: 2244 FSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCIE-WRRSDYCPF 2298
            F+ CH  VPPESF +  + D           C AL  YVA C    V IE WR    C  
Sbjct: 291  FTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVVIEDWRAQVGCEI 350

Query: 2299 LCSSDSTYQACVTACEPPKTCQDGILGPL-DPEHCQ-VLGEGCVCSEGTILHRRHSALCI 2356
             C  +S Y+ C   C  P +C      PL  P  C+    EGC C  G +L    +  C+
Sbjct: 351  TCPENSHYEVCGPPC--PASCPSP--APLTTPAVCEGPCVEGCQCDAGFVL---SADRCV 403

Query: 2357 P-EAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGE 2415
            P    C C  +     A  E W     G C   C+          G     P SC   GE
Sbjct: 404  PLNNGCGCWANGTYHEAGSEFW---ADGTCSQWCRCGP-----GGGSLVCTPASC-GLGE 454

Query: 2416 VALLLPTKDPCC 2427
            V  LLP+    C
Sbjct: 455  VCGLLPSGQHGC 466



 Score = 32.7 bits (73), Expect = 5.3
 Identities = 26/96 (27%), Positives = 33/96 (34%), Gaps = 17/96 (17%)

Query: 811  CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLS--VSARGPCLSGCACPQGLLRHGDACF 868
            CPA   +  C+           RTC+     LS        C  GC C    L     C 
Sbjct: 1121 CPAHSHYSICT-----------RTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCI 1169

Query: 869  LPEECPCTWKGKEYFP--GDQVMSPC-HTCVCQRGS 901
              ++C CT  G+ Y P     + S C   C C   S
Sbjct: 1170 PVQDCGCTHNGR-YLPVNSSLLTSDCSERCSCSSSS 1204


>gi|239757286 PREDICTED: similar to Fc fragment of IgG binding protein
            [Homo sapiens]
          Length = 1472

 Score =  280 bits (716), Expect = 1e-74
 Identities = 247/825 (29%), Positives = 336/825 (40%), Gaps = 105/825 (12%)

Query: 60   ATGPRCQMVYNAG---PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQ-- 114
            A G RCQ+V        E  ++CRA G  H  TFDG  Y + G  SYT+V     +    
Sbjct: 511  AAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLP 570

Query: 115  SFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHL---AKEVTHG--------GMRVQLP 163
            +FS++  N+       +  SR VS  +VG   +     +  +T G          R +LP
Sbjct: 571  AFSVEAKNE-------HRGSRRVS--YVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLP 621

Query: 164  HVMGSARLQ--QLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKD 221
              +   RL+  Q     +V       + +D    + + +         GLCGN N DP D
Sbjct: 622  VSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPAD 681

Query: 222  DLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEA-- 279
            D +T  G L  D VEF  SW+    +         L    C    P    G  +  E   
Sbjct: 682  DFLTPDGALAPDAVEFASSWKLDDGDY--------LCEDGCQNNCPACTPGQAQHYEGDR 733

Query: 280  ------LLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 333
                   L  PF  CH  + P PF   C  DLC   G+  + CR L+ YA+AC + G  +
Sbjct: 734  LCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISV 793

Query: 334  QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVD-SEIACVDGCYCPNGLIFED 392
              WR+    C + C   +  Y  C   CP SC+  A+  + S   CV+GC C  G +   
Sbjct: 794  GDWRSP-ANCPLSCPANS-RYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASG 851

Query: 393  GGCVAPAECPCEFHGTLYPPGSVVKED--C-NTCTCTSGKWECS---TAVCPA--ECSV- 443
            G CV  + C C F G    PG  V  D  C   CTC     + +      CPA   CSV 
Sbjct: 852  GACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQ 911

Query: 444  ----------------TGDIHFTTFDGRRYTFPATCQYILAKSRSSG----TFTVTLQNA 483
                            +GD H+ +FDGRR+ F  TC Y+L  S         F V ++N 
Sbjct: 912  NGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENE 971

Query: 484  PCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIP-PYTDDAFEIRRLSSV 542
              G +Q  +  ++V V   +  +  V     G VL+ D  + +P    D   ++ R    
Sbjct: 972  HRG-SQTVSYTRAVRVEA-RGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRD 1029

Query: 543  FLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQ 602
             + VRT+ G+ V YD    R+  +V   + E   GLCG FNG+  DD     G   +   
Sbjct: 1030 AV-VRTDFGLTVTYDWNA-RVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANAL 1087

Query: 603  LFGNSW--KTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEM--FAPCSAFLSPV 658
             FGNSW  +T   C     G      D  +     S   C +L      F  C + L P 
Sbjct: 1088 AFGNSWQEETRPGCGATEPGD-CPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQ 1146

Query: 659  PYFEQCRRDACRC-GQP-CLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPC 716
                 C  D C   GQ   LC  LA YA  C+  G  V        C LSC     Y  C
Sbjct: 1147 GAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEAC 1206

Query: 717  VAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQ 776
               C  +C DL  P  CG          EC EGC C  D       + C+P   C C  Q
Sbjct: 1207 SYGCPLSCGDLPVPGGCG---------SECHEGCVC--DEGFALSGESCLPLASCGCVHQ 1255

Query: 777  GVDYPPGDSDIPSLG---HCHCKD-GVMSCDSRA--PAAAC-PAG 814
            G  +PPG +  P  G    CHC++ G++SC+S +  P  AC P+G
Sbjct: 1256 GTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSG 1300



 Score =  162 bits (409), Expect = 6e-39
 Identities = 130/461 (28%), Positives = 184/461 (39%), Gaps = 49/461 (10%)

Query: 49   HPAFCDCRRFNATGPRCQM---VYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTL 105
            H   C  ++    G RC +   +    P+R   C+  G  H  +FDG  +   G  +Y L
Sbjct: 892  HQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLL 951

Query: 106  VGRHEPEGQ--SFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLP 163
            VG         +F + V N+ + GS   + +RAV    V  + + +A    + G +V + 
Sbjct: 952  VGSCGQNAALPAFRVLVENEHR-GSQTVSYTRAVR---VEARGVKVAVRREYPG-QVLVD 1006

Query: 164  HVMGSARLQQLAGYV---------IVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGN 214
             V+     Q   G V         +VR     T+ +D  + V  K+         GLCGN
Sbjct: 1007 DVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGN 1066

Query: 215  NNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVY 274
             N DP DDL    G    + + F +SWQE+     PG   +     P L           
Sbjct: 1067 FNGDPADDLALRGGGQAANALAFGNSWQEETR---PGCGATEPGDCPKLDSLVAQQLQSK 1123

Query: 275  EQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRP 332
             +C  L  P  PF  CH+ + P      C  D C   G     C ALA YA AC  AG  
Sbjct: 1124 NECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGAT 1183

Query: 333  LQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFED 392
            +  WR++   C + C   +  Y  C   CP SC            C +GC C  G     
Sbjct: 1184 VHPWRSE-ELCPLSCPPHSH-YEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSG 1241

Query: 393  GGCVAPAECPCEFHGTLYPPGSVVKED--CNT-CTCTSGKW-ECSTAVC----------- 437
              C+  A C C   GT +PPG        C++ C C  G    C ++ C           
Sbjct: 1242 ESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGG 1301

Query: 438  --------PAECSVTGDIHFTTFDGRRYTFPATCQYILAKS 470
                     + C  +GD H+TTFDGRR+ F  TC Y+LA++
Sbjct: 1302 SLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQT 1342



 Score =  115 bits (287), Expect = 8e-25
 Identities = 111/421 (26%), Positives = 162/421 (38%), Gaps = 61/421 (14%)

Query: 798  GVMSCDSRAPA---AACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGC 854
            G+   D R+PA    +CPA   +  C         +   +C       + S R PC+ GC
Sbjct: 790  GISVGDWRSPANCPLSCPANSRYELCGP-------ACPTSCNGAAAPSNCSGR-PCVEGC 841

Query: 855  ACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSP--C-HTCVCQRGSFQCTLHPCAS 911
             C  G +  G AC     C CT++G +  PG +V +   C   C C   + Q T     S
Sbjct: 842  VCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQS 901

Query: 912  ----------------------TCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD---- 945
                                  TC   GD HY +FDG  FDF+G C   LV S       
Sbjct: 902  CPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL 961

Query: 946  VSFSVIVENVNCYSSGMICRKFISINVGNSLI---------VFDDDSGNPSPESFLDDKQ 996
             +F V+VEN +  S  +   + + +      +         V  DD     P    D   
Sbjct: 962  PAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADG-- 1019

Query: 997  EVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTP 1056
            +V  +R G   +V      +T+ +D    V  +    +   L GLCGNF+    +++   
Sbjct: 1020 QVQVFRQGRDAVVR-TDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALR 1078

Query: 1057 ENLELTNPQEFGSSWAAVECP--DTLDPRDMCVLNPL--REPFAKKECSILLSE--VFEI 1110
               +  N   FG+SW     P     +P D   L+ L  ++  +K EC IL      F  
Sbjct: 1079 GGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRE 1138

Query: 1111 CHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYD 1169
            CH  +D      +C+ D   C   G     C +++ YA  C   G  V  WR+  LCP  
Sbjct: 1139 CHSKLDPQGAVRDCVYDR--CLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLS 1196

Query: 1170 C 1170
            C
Sbjct: 1197 C 1197



 Score = 98.6 bits (244), Expect = 8e-20
 Identities = 82/297 (27%), Positives = 126/297 (42%), Gaps = 27/297 (9%)

Query: 895  CVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD----VSFSV 950
            C    G   C     A  C A GD HY TFDG  +D +G C   +V+  S+     +FSV
Sbjct: 516  CQVVGGKAGCVAESTA-VCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSV 574

Query: 951  IVENVN------CYSSGMICRKF---ISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTW 1001
              +N +       Y   +  R +   +S+  G    V  D+  +  P S  + +  V+  
Sbjct: 575  EAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQS 634

Query: 1002 RVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLEL 1061
                   + F    +T  WD +  + + A  ++Q Q+ GLCGN++    ++  TP+    
Sbjct: 635  GPRAVVELVFGLV-VTYDWDCQLALSLPA--RFQDQVCGLCGNYNGDPADDFLTPDGALA 691

Query: 1062 TNPQEFGSSWAAVE----CPDTLDPR-DMCVLNPLREPFAKKECSIL--LSEVFEICHPV 1114
             +  EF SSW   +    C D        C     +     + C +L  L   F +CH  
Sbjct: 692  PDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDT 751

Query: 1115 VDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1170
            +D   F   C+ D   C  GG+    C  +SAYA  C + G++V DWR+P  CP  C
Sbjct: 752  LDPRPFLEQCVYDL--CVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSC 806



 Score = 91.3 bits (225), Expect = 1e-17
 Identities = 115/456 (25%), Positives = 171/456 (37%), Gaps = 78/456 (17%)

Query: 1962 GLAEALATTTEANTSTTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLA 2021
            GLA+A+   T A+   T +   E  C    C  GQ                 RC +    
Sbjct: 480  GLAKAIGYATAADCGRTVLSPVEPSCEGMQCAAGQ-----------------RCQV---- 518

Query: 2022 VRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQ--SPDEMLTVHVLD 2079
              VGG   C + E    C    D  + TFDG    +     Y + +  S D+ L    ++
Sbjct: 519  --VGGKAGC-VAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVE 575

Query: 2080 CKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRK-VTVDLQPVWPPVS--RYGFRIED 2136
             K+ + G        LV +     +H V++ R     V VD Q    PVS      R+  
Sbjct: 576  AKNEHRGSRRVSYVGLVTVRA--YSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQ 633

Query: 2137 TGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVG 2196
            +G   ++     + + +     L +   ++    Q  GLCG  +GD A+D    DG++  
Sbjct: 634  SGPRAVVELVFGLVVTYDWDCQLALSLPARFQD-QVCGLCGNYNGDPADDFLTPDGAL-- 690

Query: 2197 GAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCL----------RMVSNRT--- 2243
             A D   F  SW++              D C   +C  C           R+    T   
Sbjct: 691  -APDAVEFASSWKLDDG------DYLCEDGCQN-NCPACTPGQAQHYEGDRLCGMLTKLD 742

Query: 2244 --FSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCI-EWRRSDYC 2296
              F+ CH  + P  F E  + D   V       C  L+ Y   C +  + + +WR    C
Sbjct: 743  GPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANC 802

Query: 2297 PFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHC--QVLGEGCVCSEGTILHRRHSAL 2354
            P  C ++S Y+ C  AC  P +C     G   P +C  +   EGCVC  G +        
Sbjct: 803  PLSCPANSRYELCGPAC--PTSCN----GAAAPSNCSGRPCVEGCVCLPGFV---ASGGA 853

Query: 2355 CIPEAKCACTDSMGVPRALG-ETWNSSLSGCCQHQC 2389
            C+P + C CT   G+  A G E W   L   CQ +C
Sbjct: 854  CVPASSCGCT-FQGLQLAPGQEVWADEL---CQRRC 885



 Score = 78.6 bits (192), Expect = 8e-14
 Identities = 118/489 (24%), Positives = 165/489 (33%), Gaps = 103/489 (21%)

Query: 1983 AEQDCVRHICLEGQLIRVN--QSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCS 2040
            A++ C R     G   +V     Q CP G    RC     +V+ G   C P     C+ S
Sbjct: 877  ADELCQRRCTCNGATHQVTCRDKQSCPAGE---RC-----SVQNGLLGCYPDRFGTCQGS 928

Query: 2041 IFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNM 2100
               D  +V+FDG          Y+L  S  +   +                P   V++  
Sbjct: 929  --GDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL----------------PAFRVLVEN 970

Query: 2101 THLAHQVTIDRFNRKVTVDLQPVWPPVSRY--GFRIEDTGHMYMILTPSDIQIQWLHSSG 2158
             H   Q     + R V V+ + V   V R   G  + D    Y+    +D Q+Q      
Sbjct: 971  EHRGSQTV--SYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGR 1028

Query: 2159 LMIVEA---------------SKTSKAQGHGLCGIC---DGDAANDLTLKDGSVVGGAED 2200
              +V                 +K   +    LCG+C   +GD A+DL L+ G   G A +
Sbjct: 1029 DAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGG---GQAAN 1085

Query: 2201 PAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRT----------FSACHRF 2250
               F +SWQ     T  G     P  C   D     ++ S             F  CH  
Sbjct: 1086 ALAFGNSWQEE---TRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSK 1142

Query: 2251 VPPESFCELWIRDTKYVQ--------QPCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCS 2301
            + P+      +RD  Y +          C AL  Y A C      +  WR  + CP  C 
Sbjct: 1143 LDPQGA----VRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCP 1198

Query: 2302 SDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKC 2361
              S Y+AC   C  P +C D  +       C    EGCVC EG  L       C+P A C
Sbjct: 1199 PHSHYEACSYGC--PLSCGDLPVPGGCGSECH---EGCVCDEGFAL---SGESCLPLASC 1250

Query: 2362 ACTDSMGVPRALGETW-------------NSSLSGCCQHQCQAPDTIVPV--DLGCPSPR 2406
             C    G     G+T+                L  C    C   +   P    LGC +  
Sbjct: 1251 GCV-HQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVG 1309

Query: 2407 PESCLRFGE 2415
              +C   G+
Sbjct: 1310 SSTCQASGD 1318



 Score = 68.9 bits (167), Expect = 7e-11
 Identities = 47/156 (30%), Positives = 66/156 (42%), Gaps = 35/156 (22%)

Query: 850  CLSGCACPQGLLRHGDACFLPEECPCTWKG------KEYFPGDQVMSPCHTCVCQRGSF- 902
            C  GC C +G    G++C     C C  +G      + ++PG    S CH   CQ G   
Sbjct: 1227 CHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCH---CQEGGLV 1283

Query: 903  QCTLHPC-------------------ASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKST 943
             C    C                   +STC A GD HY TFDG  FDF+G C V+++  T
Sbjct: 1284 SCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTC-VYVLAQT 1342

Query: 944  SDV-----SFSVIVENVNCYSSGMICRKFISINVGN 974
                     F+V+ ENV   +  +   + I++ V N
Sbjct: 1343 CGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVAN 1378



 Score = 32.7 bits (73), Expect = 5.3
 Identities = 22/77 (28%), Positives = 30/77 (38%), Gaps = 11/77 (14%)

Query: 1992 CLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFD 2051
            C EG L+    S   P  A  P  G LG         C  +    C+ S   D  + TFD
Sbjct: 1277 CQEGGLVSCESSSCGPHEACQPSGGSLG---------CVAVGSSTCQAS--GDPHYTTFD 1325

Query: 2052 GSHVALFKEAIYILSQS 2068
            G         +Y+L+Q+
Sbjct: 1326 GRRFDFMGTCVYVLAQT 1342


>gi|239755776 PREDICTED: similar to Mucin-19 [Homo sapiens]
          Length = 1950

 Score =  268 bits (686), Expect = 4e-71
 Identities = 171/552 (30%), Positives = 262/552 (47%), Gaps = 43/552 (7%)

Query: 301  CTSDLCQSMGDVATWCRALAEYARACAQAGR-PLQGWRTQLRQC--TVHCKEKAFTYNEC 357
            C  + CQ+    +T C   +E +R CA  G    + WR+       T  C E+   Y EC
Sbjct: 692  CIDEYCQTRDKTST-CDTYSELSRLCASDGPGTFESWRSDSDVVCETQRCPEQHI-YKEC 749

Query: 358  IACCPASCHPRASCVDSEIACVDGCYCPNGLIFED----GGCVAPAECPCEFHGTLYPPG 413
                PA+C   A   DSE  CV GC CP G + +D    G CV  AECPCE  GT+Y PG
Sbjct: 750  GPSNPATCSNVAPFQDSE--CVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPG 807

Query: 414  SVVKEDCNT-CTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRS 472
             V +  C + CTC   KW C+ A+CP  C V G    TTFDG +Y FP  C ++   +  
Sbjct: 808  EVREGPCGSQCTCQDAKWSCTEALCPGRCKVEGS-SLTTFDGVKYNFPGNCHFLAVHNED 866

Query: 473  SGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDD 532
               ++++++  PC   Q G C+ SV+++L+        +  +   +  D+ +    Y  D
Sbjct: 867  ---WSISVELRPCPSGQTGTCLNSVTLLLNSSVPVDKYVFNSDGTVTNDKIRNQGYYYSD 923

Query: 533  AFEIRRLSSVFLRVRTNVGVRV-LYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFL 591
              +I   SS +L+V T   V++ +     ++LY+ +      DTVGLCG++N   +DDF+
Sbjct: 924  KIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFM 983

Query: 592  SPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVL--TGEMFA 649
            S   + E T Q F NSW+ +S       G+P   C + ++   ++ + C +L  +    A
Sbjct: 984  SSQNILEKTSQAFANSWEMMSC----PKGNP-SSC-ISIEKEKFAERHCGILLDSSGPLA 1037

Query: 650  PCSAFLSPVPYFEQCRRDACRC--GQPCLCATLAHYAHLC-RRHGLPVDFRARLPACALS 706
             C   ++P PY E+C++  C C   Q CLC  L +Y   C  +    V +R  L  C  S
Sbjct: 1038 SCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGL--CEHS 1095

Query: 707  CEASKEYSPCVAPCGRTCQDLASPE-ACGVDGGDDLSRDECVEGCACPPDTYLDTQADLC 765
            C +   +   V  C  +C+ L+  + +C V+       D  V+GC CP   Y + + + C
Sbjct: 1096 CPSGLVFKYNVKACNSSCRSLSERDRSCDVE-------DVPVDGCTCPDAMYQNNEGN-C 1147

Query: 766  VPRNQCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAA--CPAGQVFVNCSDL 823
            V ++QC C+       PG         C C+DG++ C          C  G  +V+CSD 
Sbjct: 1148 VLKSQCDCYINDEVMQPGKLIHTDDNKCVCRDGILLCQIPIDLTLQNCSGGAEYVDCSD- 1206

Query: 824  HTDLELSRERTC 835
                +    RTC
Sbjct: 1207 -PKAQRRTNRTC 1217



 Score =  126 bits (316), Expect = 3e-28
 Identities = 103/403 (25%), Positives = 162/403 (40%), Gaps = 41/403 (10%)

Query: 785  SDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSV 844
            SD P        D  + C+++     CP   ++  C         S   TC     N++ 
Sbjct: 718  SDGPGTFESWRSDSDVVCETQR----CPEQHIYKECGP-------SNPATCS----NVAP 762

Query: 845  SARGPCLSGCACPQGLLRHG----DACFLPEECPCTWKGKEYFPGDQVMSPCHT-CVCQR 899
                 C+SGC CP+G L         C L  ECPC   G  Y PG+    PC + C CQ 
Sbjct: 763  FQDSECVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGEVREGPCGSQCTCQD 822

Query: 900  GSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYS 959
              + CT   C   C   G     TFDG+ ++F G C   L     D S SV +       
Sbjct: 823  AKWSCTEALCPGRCKVEGSS-LTTFDGVKYNFPGNCHF-LAVHNEDWSISVELRPCPSGQ 880

Query: 960  SGMICRKFISINVGNSL----IVFDDDSGNPSPES-----FLDDKQEVHTWRVGFFTLVH 1010
            +G  C   +++ + +S+     VF+ D    + +      +  DK ++      +  +  
Sbjct: 881  TGT-CLNSVTLLLNSSVPVDKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASSSYLQVET 939

Query: 1011 FPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSS 1070
            +    + +       ++V   P       GLCG+++ K  ++  + +N+     Q F +S
Sbjct: 940  YFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANS 999

Query: 1071 WAAVECPDTLDPRDMCVLNPLREPFAKKECSILL--SEVFEICHPVVDVTWFYSNCLTDT 1128
            W  + CP   +P     +   +E FA++ C ILL  S     CHP+V+   ++  C   T
Sbjct: 1000 WEMMSCPKG-NPSSCISIE--KEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYT 1056

Query: 1129 CGCSQGGDCECFCASVSAYAHQCCQ-HGVAVDWRTPRLCPYDC 1170
            C C    D  C C  +  Y   C +     V WRT  LC + C
Sbjct: 1057 CTCENSQD--CLCTILGNYVKACAEKETYIVGWRT-GLCEHSC 1096



 Score =  112 bits (281), Expect = 4e-24
 Identities = 125/511 (24%), Positives = 179/511 (35%), Gaps = 97/511 (18%)

Query: 33   CAPSYLFSCFNG-GECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRA--------W- 82
            C   YL       G+CV  A C C            VY  G  R+  C +        W 
Sbjct: 774  CPEGYLLDDIGEKGKCVLKAECPCESSGT-------VYQPGEVREGPCGSQCTCQDAKWS 826

Query: 83   -------GQHHVE-----TFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSP 130
                   G+  VE     TFDG+ Y   G   +  V       + +SI V   P      
Sbjct: 827  CTEALCPGRCKVEGSSLTTFDGVKYNFPGNCHFLAV-----HNEDWSISVELRPCPSGQT 881

Query: 131  YTCSRAVSLFF-----VGEQEIHLAKEVTHGGMRVQ-------LPHVMGSARLQQLAGYV 178
             TC  +V+L       V +   +    VT+  +R Q       +     S+   Q+  Y 
Sbjct: 882  GTCLNSVTLLLNSSVPVDKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASSSYLQVETYF 941

Query: 179  IVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFV 238
             V+ Q            +Y+ M P     T GLCG+ N   +DD ++S   L      F 
Sbjct: 942  HVKLQIQIVPVMQ----LYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFA 997

Query: 239  HSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQ------CEALLRP--PFDACHA 290
            +SW+  +                C + NP +   + ++      C  LL    P  +CH 
Sbjct: 998  NSWEMMS----------------CPKGNPSSCISIEKEKFAERHCGILLDSSGPLASCHP 1041

Query: 291  YVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKE- 349
             V+P P+   C    C         C  L  Y +ACA+    + GWRT L  C   C   
Sbjct: 1042 IVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGL--CEHSCPSG 1099

Query: 350  KAFTYNECIACCPASCH---PRASCVDSEIACVDGCYCPNGLI-FEDGGCVAPAECPCEF 405
              F YN  +  C +SC     R    D E   VDGC CP+ +    +G CV  ++C C  
Sbjct: 1100 LVFKYN--VKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYI 1157

Query: 406  HGTLYPPGSVVKEDCNTCTCTSG-----------KWECSTAVCPAECSVTGDIHFTTFDG 454
            +  +  PG ++  D N C C  G              CS      +CS       T    
Sbjct: 1158 NDEVMQPGKLIHTDDNKCVCRDGILLCQIPIDLTLQNCSGGAEYVDCSDPKAQRRTNRTC 1217

Query: 455  RRYTFPATCQYILAKSRSSGTFTVTLQNAPC 485
                 P    Y       +GTF +  ++ PC
Sbjct: 1218 STRNIPVFDDYC---GHENGTFRILTESVPC 1245



 Score =  105 bits (263), Expect = 5e-22
 Identities = 51/142 (35%), Positives = 75/142 (52%), Gaps = 1/142 (0%)

Query: 1034 WQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSW-AAVECPDTLDPRDMCVLNPLR 1092
            +QG++ GLCGN +    ++  T  +   +   EFG+SW  + EC DT+     C  NP  
Sbjct: 1260 FQGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQTFPCDSNPYC 1319

Query: 1093 EPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCC 1152
            + +A ++C IL    F  CH  VD + ++  C+ + C C   G    FC +V+ YA  C 
Sbjct: 1320 KAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACS 1379

Query: 1153 QHGVAVDWRTPRLCPYDCDFFN 1174
              GV V WR P LCP  CD++N
Sbjct: 1380 AVGVCVSWRKPNLCPVYCDYYN 1401



 Score =  105 bits (262), Expect = 6e-22
 Identities = 76/246 (30%), Positives = 104/246 (42%), Gaps = 29/246 (11%)

Query: 577  GLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYS 636
            GLCG  NG+ +DDF +      S    FGNSWKT   CS  V+ +   PCD +    +++
Sbjct: 1266 GLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQT--FPCDSNPYCKAWA 1323

Query: 637  VQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQP----CLCATLAHYAHLCRRHGL 692
            V+ C +L    F  C   + P  Y + C  +AC C         C  +A YA  C   G+
Sbjct: 1324 VRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGV 1383

Query: 693  PVDFRARLPACALSC-------EASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDE 745
             V +R +   C + C       E    Y PC     +TC+D           G   S   
Sbjct: 1384 CVSWR-KPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLV--------GQKFS--S 1432

Query: 746  CVEGC--ACPPDT-YLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGH-CHCKDGVMS 801
             +EGC   CP    YLD     CV  ++CSC +  V  P G     + G  C+C  G + 
Sbjct: 1433 LLEGCYAKCPDSAPYLDENTMKCVSLSECSCFYNDV-IPAGGVIEDNCGRTCYCIAGQLE 1491

Query: 802  CDSRAP 807
            C   AP
Sbjct: 1492 CSETAP 1497



 Score = 99.0 bits (245), Expect = 6e-20
 Identities = 74/239 (30%), Positives = 107/239 (44%), Gaps = 26/239 (10%)

Query: 210  GLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGT 269
            GLCGNNN D KDD  T    +    +EF +SW+    +Q    T +     PC   NP  
Sbjct: 1266 GLCGNNNGDLKDDFTTRYSSVASGALEFGNSWK---TSQECSDTVAQ--TFPC-DSNPYC 1319

Query: 270  MQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSD--LCQSMGDVATWCRALAEYARACA 327
                  +CE L    F  CH  V P  +   C  +   C   G    +C A+A YA AC+
Sbjct: 1320 KAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACS 1379

Query: 328  QAGRPLQGWRTQLRQCTVHCK------EKAFTYNECIACCPASCHPRASCVDSEI-ACVD 380
              G     WR +   C V+C       E  + Y  C      +C  +   V  +  + ++
Sbjct: 1380 AVG-VCVSWR-KPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTC--KDQLVGQKFSSLLE 1435

Query: 381  GCY--CPNGLIFEDGG---CVAPAECPCEFHGTLYPPGSVVKEDC-NTCTCTSGKWECS 433
            GCY  CP+   + D     CV+ +EC C F+  + P G V++++C  TC C +G+ ECS
Sbjct: 1436 GCYAKCPDSAPYLDENTMKCVSLSECSC-FYNDVIPAGGVIEDNCGRTCYCIAGQLECS 1493



 Score = 75.5 bits (184), Expect = 7e-13
 Identities = 56/207 (27%), Positives = 89/207 (42%), Gaps = 26/207 (12%)

Query: 2174 GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDS---CATT 2230
            GLCG  +GD  +D T +  SV  GA +   F +SW+     +      F  DS   C   
Sbjct: 1266 GLCGNNNGDLKDDFTTRYSSVASGALE---FGNSWKTSQECSDTVAQTFPCDSNPYCKAW 1322

Query: 2231 DCSPCLRMVSNRTFSACHRFVPPESFCELWIRDT-------KYVQQPCVALTVYVAMCHK 2283
                C  ++ + TF  CH  V P ++ ++ I +        KY+   C A+ +Y   C  
Sbjct: 1323 AVRKC-EILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGF-CTAVAMYAEACSA 1380

Query: 2284 FHVCIEWRRSDYCPFLCSSDSTYQACVTACEP-----PKTCQDGILGPLDPEHCQVLGEG 2338
              VC+ WR+ + CP  C   +    C    EP      KTC+D ++G    +    L EG
Sbjct: 1381 VGVCVSWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVG----QKFSSLLEG 1436

Query: 2339 CV--CSEGTILHRRHSALCIPEAKCAC 2363
            C   C +       ++  C+  ++C+C
Sbjct: 1437 CYAKCPDSAPYLDENTMKCVSLSECSC 1463



 Score = 73.6 bits (179), Expect = 3e-12
 Identities = 124/529 (23%), Positives = 189/529 (35%), Gaps = 80/529 (15%)

Query: 1336 CEWRYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCP-TPQVLDEVTQRCVYLEDC--- 1391
            C W Y+ C +   +TC+D +    +    +EGC   CP +   LDE T +CV L +C   
Sbjct: 1406 CRWHYEPCGTVTAKTCKD-QLVGQKFSSLLEGCYAKCPDSAPYLDENTMKCVSLSECSCF 1464

Query: 1392 ---VEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTAL 1448
               V PA  V  +  G  T     G    S+  P  S  +  T T    L+  A +T   
Sbjct: 1465 YNDVIPAGGVIEDNCG-RTCYCIAGQLECSETAPTNSTFAVSTTTATTILSTGAAITLVT 1523

Query: 1449 NPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSS 1508
              P TA   P ++   ++TT              GP   P + G+T + + I  T  ++ 
Sbjct: 1524 GGPSTAASIPAITTSSSETT----------GTTLGPLTEPFTTGITETSVPIISTSGNAG 1573

Query: 1509 LPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLP 1568
            +   +     G    A  T  V     G+ +   S R+   PR    T AV   G GS P
Sbjct: 1574 MTGVVSPTVTGASGMAGTTGGVDAATTGAASENTSERA-GTPRVSGATPAV---GGGSTP 1629

Query: 1569 VRTTPLQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQS 1628
                P      A+ S     S G+I+ SP +S         A +   S++G   P+    
Sbjct: 1630 GEAGP-----GATVSGSTGVSAGSITASPGAS---------ATSSESSKSGTTGPSVGGK 1675

Query: 1629 ASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAP 1688
              + S+  T +   +     S  +T   +  ++ +    G      SP      P P +P
Sbjct: 1676 TGATSSEATSSEGMSGVTGQSLGSTAGSDSEITAKTSFTG-----SSPPGKLTRPSPGSP 1730

Query: 1689 PRPAQHTT------------------MATRSPALPPETPAAASLSTATDG---------- 1720
               +  TT                  + +   ++   T A +  +  T G          
Sbjct: 1731 GHFSGGTTEWGNVATTGAAGENTSGALGSTEGSVEATTSAGSGNTAGTSGTGDTGPGNTA 1790

Query: 1721 LAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAPVA----TPGPKASVITTPLQPQA 1776
            ++ TP +S  +T P    S  P +  +     G S        T    A +  TP    A
Sbjct: 1791 VSGTPVVSPGAT-PGAPGSSTPGEADIGNTSFGKSGKSGHDSLTVLNPAFLRRTPTVSAA 1849

Query: 1777 TTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSG 1825
            +T    T SPV   T AA   A   +   P   GT  G   G  + TSG
Sbjct: 1850 ST----TSSPVSKHTDAASATAVTISGSKPGTPGTPGGATSGGKI-TSG 1893



 Score = 49.7 bits (117), Expect = 4e-05
 Identities = 91/424 (21%), Positives = 152/424 (35%), Gaps = 59/424 (13%)

Query: 1975 TSTTCVPIAEQDCVRHI-CLEGQLIR-VNQSQHCPQGAAPPRCGILGLAVRVG------- 2025
            T +   P  + +CV    C EG L+  + +   C   A  P C   G   + G       
Sbjct: 756  TCSNVAPFQDSECVSGCTCPEGYLLDDIGEKGKCVLKAECP-CESSGTVYQPGEVREGPC 814

Query: 2026 GDRC--------CPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHV 2077
            G +C        C    C  RC +    S  TFDG          ++   + D  ++V +
Sbjct: 815  GSQCTCQDAKWSCTEALCPGRCKV-EGSSLTTFDGVKYNFPGNCHFLAVHNEDWSISVEL 873

Query: 2078 LDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDR--FNRKVTVDLQPVWPPVSRYGFRIE 2135
              C S   G       CL  + +  L   V +D+  FN   TV    +      Y  +I+
Sbjct: 874  RPCPSGQTGT------CLNSVTLL-LNSSVPVDKYVFNSDGTVTNDKIRNQGYYYSDKIQ 926

Query: 2136 --DTGHMYMILTPS---DIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLK 2190
              +    Y+ +       +QIQ +    L  V           GLCG  +  A +D    
Sbjct: 927  IFNASSSYLQVETYFHVKLQIQIVPVMQLY-VSMPPNQFTDTVGLCGSYNNKAEDDFMSS 985

Query: 2191 DGSVVGGAEDPAPFLDSWQV-------PSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRT 2243
               +   ++    F +SW++       PSS  S+ + +F    C        + + S+  
Sbjct: 986  QNILEKTSQ---AFANSWEMMSCPKGNPSSCISIEKEKFAERHCG-------ILLDSSGP 1035

Query: 2244 FSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCIEWRRSDYCPFL 2299
             ++CH  V P+ + E   + T   +      C  L  YV  C +    I   R+  C   
Sbjct: 1036 LASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHS 1095

Query: 2300 CSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEA 2359
            C S   ++  V AC              D E   V  +GC C +   +++ +   C+ ++
Sbjct: 1096 CPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPV--DGCTCPDA--MYQNNEGNCVLKS 1151

Query: 2360 KCAC 2363
            +C C
Sbjct: 1152 QCDC 1155



 Score = 42.7 bits (99), Expect = 0.005
 Identities = 41/187 (21%), Positives = 71/187 (37%), Gaps = 49/187 (26%)

Query: 810  ACPAGQVFVN----CSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGD 865
            +CP+G VF      C+     L   R+R+C+ + + +          GC CP  + ++ +
Sbjct: 1095 SCPSGLVFKYNVKACNSSCRSLS-ERDRSCDVEDVPVD---------GCTCPDAMYQNNE 1144

Query: 866  A-CFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQC------TLHPCAS------- 911
              C L  +C C    +   PG  + +  + CVC+ G   C      TL  C+        
Sbjct: 1145 GNCVLKSQCDCYINDEVMQPGKLIHTDDNKCVCRDGILLCQIPIDLTLQNCSGGAEYVDC 1204

Query: 912  --------TCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSSGMI 963
                    T      R+   FD    D+ G           + +F ++ E+V C   G+ 
Sbjct: 1205 SDPKAQRRTNRTCSTRNIPVFD----DYCG---------HENGTFRILTESVPCCEDGLT 1251

Query: 964  CRKFISI 970
            C + I +
Sbjct: 1252 CSRKIIV 1258


>gi|134268640 tectorin alpha precursor [Homo sapiens]
          Length = 2155

 Score =  237 bits (605), Expect = 1e-61
 Identities = 210/797 (26%), Positives = 321/797 (40%), Gaps = 105/797 (13%)

Query: 73   PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHND-PQCGSSPY 131
            P+R+++C       + TFDG  Y    + SYTL+       +   I ++   P  G +  
Sbjct: 707  PKRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERPEYLEIDINKKKPDAGPAWL 766

Query: 132  TCSRAVSLFFVGEQEIHL----AKEVTHGGMRVQLP--HVMGSARLQQLAGYVIVRHQSA 185
               R +    V +QE+ +    A EV   G  V+LP  H  G   + +      V  +  
Sbjct: 767  RGLRIL----VADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVESKGV 822

Query: 186  FTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ--E 243
             T+ +     +YI++S      T GLCG  NA+  D+    +GK TD++  F+ SW   E
Sbjct: 823  VTVQYSDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTFE 882

Query: 244  QAPNQPPGPTTSSLPRPPCLQQNPGTMQGVY---EQCEALLRP---PFDACHAYVSPLPF 297
            +  N   G    +         N   +   Y    +C  +  P    F  CH  V+   +
Sbjct: 883  EICNGECGDLLKAC-------NNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAY 935

Query: 298  TASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNEC 357
              +C   LCQS G+ +  C ++A YA AC  A   +  WRT    C + C E +  + EC
Sbjct: 936  YRTCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRT-YDFCPLECPENSH-FEEC 993

Query: 358  IACCPASCHPRA---SCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGS 414
            I  C  +C        CVDS   C +GC C  G       CV  +EC C F G       
Sbjct: 994  IT-CTETCETLTLGPICVDS---CSEGCQCDEGYALLGSQCVTRSECGCNFEGHQLATNE 1049

Query: 415  V--VKEDCNT---CTCTSGKWECSTAVC-------------------PAECSVTGDIHFT 450
               V  DC     C+ T  +  C T  C                    A C V+G  H+ 
Sbjct: 1050 TFWVDLDCQIFCYCSGTDNRVHCETIPCKDDEYCMEEGGLYYCQARTDASCIVSGYGHYL 1109

Query: 451  TFDGRRYTFPATCQYILA------KSRSSGTFTVTLQN------APCGLNQDGACVQSVS 498
            TFDG  + F  +C  IL        S S   F VT +N          + Q    V   S
Sbjct: 1110 TFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNEDRDPSLALWVKQVDVTVFGYS 1169

Query: 499  VILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVF-LRVRTNVGVRVLYD 557
            +++H+  +  V         L +  ++  P      +I   S  F + V T+ G++V+YD
Sbjct: 1170 IVIHRAYKHTV---------LVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYD 1220

Query: 558  REGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPL 617
             +   L + V +     T GLCG +NGN  DD   P+G+  S+   FG SW        +
Sbjct: 1221 WKTF-LSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKRDTFCQV 1279

Query: 618  VSGSPLDPCDVHLQAASYSVQACSVLTGE--MFAPCSAFLSPVPYFEQCRRDACRCG--Q 673
              G     C   ++  S   Q CS++  +   F+ C + ++P  +++ C  D+C  G   
Sbjct: 1280 GCGDRCPSC-AKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGAV 1338

Query: 674  PCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEAC 733
               C+ L +YA  C+  G+ V       +C ++C  +  Y  CV+ C   C  +     C
Sbjct: 1339 QTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCAAIRLKSDC 1398

Query: 734  GVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPP----GDSDIPS 789
                        CVEGC C     L+ ++  C+  + C C+  G  Y P     +SD   
Sbjct: 1399 S---------HYCVEGCHCDAGYVLNGKS--CILPHSCGCYSDGKYYEPKQLFWNSDCTR 1447

Query: 790  LGHCHC-KDGVMSCDSR 805
               C C +  V+ CD R
Sbjct: 1448 --RCRCFRRNVIQCDPR 1462



 Score =  202 bits (513), Expect = 5e-51
 Identities = 200/816 (24%), Positives = 318/816 (38%), Gaps = 78/816 (9%)

Query: 41   CFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGK 100
            C +    ++     C  +    P+ +  Y +  E  S C  +G+ H  TFDG  ++  G 
Sbjct: 285  CLDFNNEIYCQEASCSPYEVCEPKGKFFYCSAVET-STCVVFGEPHYHTFDGFLFHFQGS 343

Query: 101  GSYTLVGRHEPEGQS---FSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGG 157
             +Y L+ R   +  S   FS++  N+ + GS+  +  + +S+   G +   L  + ++G 
Sbjct: 344  CAY-LLARQCLQTSSLPFFSVEAKNEHRRGSA-VSWVKELSVEVNGYKI--LIPKGSYGR 399

Query: 158  MRVQ-----LPHVM--GSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHG 210
            ++V      LP  +  G+ ++ Q      V       + +DG     I +    +  T G
Sbjct: 400  VKVNDLVTSLPVTLDLGTVKIYQSGISTAVETDFGLLVTFDGQHYASISVPGSYINSTCG 459

Query: 211  LCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTM 270
            LCGN N +P DD +   G+    V++   SW+    +        S     C Q +  T 
Sbjct: 460  LCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHADWK----CDSGCVDNCTQCDAAT- 514

Query: 271  QGVY---EQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARA 325
            + +Y   + C  L +   P   C   V P  F  SC  DLC    +    C+A+  YA  
Sbjct: 515  EALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALV 574

Query: 326  CAQAGRPLQGWRTQLR-QCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYC 384
            C   G P+  WRTQ     TV C   +  Y+ C + CP +C    +  +    C +GC C
Sbjct: 575  CQALGIPIGDWRTQTGCVSTVQCPSFSH-YSVCTSSCPDTCSDLTASRNCATPCTEGCEC 633

Query: 385  PNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCN---TCTCTSG-------KWECST 434
              G +     CV   +C C+F G  Y  G       N    C C  G       K   S 
Sbjct: 634  NQGFVLSTSQCVPLHKCGCDFDGHYYTMGEFFWATANCTVQCLCEEGGDVYCFNKTCGSG 693

Query: 435  AVCPAE-------------CSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQ 481
             VC  E             C ++ +    TFDG  Y FP+   Y L K+       + + 
Sbjct: 694  EVCAVEDGYQGCFPKRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERPEYLEID 753

Query: 482  NAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPY-TDDAFEIRRLS 540
                  +   A ++ + +++  D   ++    A +V L  Q   +P +      EI R +
Sbjct: 754  INKKKPDAGPAWLRGLRILV-ADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYR-N 811

Query: 541  SVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPEST 600
                 V +   V V Y   GL LY+++   +   T GLCG +N N  D+F  P G     
Sbjct: 812  KNSTTVESKGVVTVQYSDIGL-LYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDN 870

Query: 601  PQLFGNSWKTLSACSPLVSGSPLDPC--DVHLQAASYSVQACSVL---TGEMFAPCSAFL 655
              +F  SW T         G  L  C  D  L     S   C ++   +   F  C   +
Sbjct: 871  LAVFLESWTTFEEICNGECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVV 930

Query: 656  SPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEY 713
            +   Y+  C    C+ G  +  LC ++A YA  C+   + V        C L C  +  +
Sbjct: 931  NVTAYYRTCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHF 990

Query: 714  SPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSC 773
              C+  C  TC+ L     C          D C EGC C  D         CV R++C C
Sbjct: 991  EECIT-CTETCETLTLGPIC---------VDSCSEGCQC--DEGYALLGSQCVTRSECGC 1038

Query: 774  HFQGVDYPPGDS---DIPSLGHCHCK--DGVMSCDS 804
            +F+G      ++   D+     C+C   D  + C++
Sbjct: 1039 NFEGHQLATNETFWVDLDCQIFCYCSGTDNRVHCET 1074



 Score =  182 bits (461), Expect = 5e-45
 Identities = 185/718 (25%), Positives = 268/718 (37%), Gaps = 72/718 (10%)

Query: 68   VYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGR-HEPEGQSFS---IQVHND 123
            +Y      D+ C   G  H  TFDG  +         L      P   SF    +   N+
Sbjct: 1089 LYYCQARTDASCIVSGYGHYLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNE 1148

Query: 124  PQCGSSPYTCSRAVSLFFVGEQEIHLAKE--VTHGGMRVQLPHVMGSARLQ--QLAGYVI 179
             +  S      +     F     IH A +  V     R+ LP  +G  ++       +V+
Sbjct: 1149 DRDPSLALWVKQVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVV 1208

Query: 180  VRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVH 239
            V       + +D  + + I +   +   T+GLCG  N +P DDL    G L   V EF  
Sbjct: 1209 VETDFGLKVVYDWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQ 1268

Query: 240  SWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEAL--LRPPFDACHAYVSPLPF 297
            SW ++      G        P C +        V + C  +      F  CH+ V+P  F
Sbjct: 1269 SWVKRDTFCQVGCGDRC---PSCAKVEG--FSKVQQLCSLIPNQNAAFSKCHSKVNPTFF 1323

Query: 298  TASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNEC 357
              +C  D C   G V T C  L  YA  C   G  + GWR     CTV C   +  Y  C
Sbjct: 1324 YKNCLFDSCIDGGAVQTACSWLQNYASTCQTQGITVTGWRNYT-SCTVTCPPNSH-YESC 1381

Query: 358  IACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVV- 416
            ++ C   C       D    CV+GC+C  G +     C+ P  C C   G  Y P  +  
Sbjct: 1382 VSVCQPRCAAIRLKSDCSHYCVEGCHCDAGYVLNGKSCILPHSCGCYSDGKYYEPKQLFW 1441

Query: 417  KEDCNT-CTC-TSGKWECSTAVCPAE-------------------CSVTGDIHFTTFDGR 455
              DC   C C      +C    C ++                   C   G   F TFDG 
Sbjct: 1442 NSDCTRRCRCFRRNVIQCDPRQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGA 1501

Query: 456  RYTFPATCQYILAKSRSSGTFTVTLQNAPCGL--NQDGACVQSVSVI---LHQDPRRQVT 510
               FPA C ++L+      T    L +    L  N D     ++++I          Q+ 
Sbjct: 1502 FLRFPANCAFVLS------TICQKLPDISFQLIINFDKWSAPNLTIISPVYFYINEEQIL 1555

Query: 511  LTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQR 570
            +     V +      +P  T  A +I   S  FL + T+  +++ Y+   + + + + +R
Sbjct: 1556 INDRNTVKVNGTQVNVPFITGLATKIYS-SEGFLVIDTSPDIQIYYNGFNV-IKISISER 1613

Query: 571  WVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKT--------LSACSPLVSGSP 622
                  GLCG FNG+  DD+++  G P  +  +   SWKT          +C+ L     
Sbjct: 1614 LQNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKTNGMQKRPLAPSCNELQFSQY 1673

Query: 623  LDPCD-VHLQAASYSVQACSVLTG--EMFAPCSAFLSPVPYFEQCRRDACRCGQPC-LCA 678
               CD VH+Q        C  LT     F PC   L P+P++E C  D C   +   LC 
Sbjct: 1674 AAMCDNVHIQKMQ-GDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYLDGCYSHKKFQLCG 1732

Query: 679  TLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCV-APC-GRTCQDLASPEACG 734
            +LA Y   CR  G+          C+   E      PCV A C  RTC+     E CG
Sbjct: 1733 SLAAYGEACRSFGILSTEWIEKENCSGVVE-----DPCVGADCPNRTCELGNGRELCG 1785



 Score =  134 bits (337), Expect = 1e-30
 Identities = 119/454 (26%), Positives = 184/454 (40%), Gaps = 56/454 (12%)

Query: 375 EIACVDGC-----YCPNGLIF-EDGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCT-- 426
           EI   +GC     +   G +F +D  C     C  +F+  +Y         C   +C+  
Sbjct: 253 EIDPANGCTSRGQFLRRGEVFWDDLNCTVKCRC-LDFNNEIY---------CQEASCSPY 302

Query: 427 -----SGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAK----SRSSGTFT 477
                 GK+   +AV  + C V G+ H+ TFDG  + F  +C Y+LA+    + S   F+
Sbjct: 303 EVCEPKGKFFYCSAVETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFS 362

Query: 478 VTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQA--GDVLLFDQYKIIPPYTDDAFE 535
           V  +N     ++ G+ V  V  +  +    ++ + +   G V + D    +P   D    
Sbjct: 363 VEAKNE----HRRGSAVSWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTV 418

Query: 536 IRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVG 595
               S +   V T+ G+ V +D +     + V   ++  T GLCG +N N  DDFL P G
Sbjct: 419 KIYQSGISTAVETDFGLLVTFDGQHYAS-ISVPGSYINSTCGLCGNYNKNPLDDFLRPDG 477

Query: 596 VPESTPQLFGNSWKTLSACSPLVSG--SPLDPCDVHLQAASYSVQACSVL--TGEMFAPC 651
            P  +    G SW+   A     SG       CD   +A  +    C  L  T      C
Sbjct: 478 RPAMSVLDLGESWRVYHADWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGPLWEC 537

Query: 652 SAFLSPVPYFEQCRRDAC--RCGQPCLCATLAHYAHLCRRHGLPV-DFRARLPACA-LSC 707
              + P  +   C  D C  R     LC  +  YA +C+  G+P+ D+R +    + + C
Sbjct: 538 GTVVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQC 597

Query: 708 EASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVP 767
            +   YS C + C  TC DL +   C            C EGC C     L T    CVP
Sbjct: 598 PSFSHYSVCTSSCPDTCSDLTASRNCAT---------PCTEGCECNQGFVLSTSQ--CVP 646

Query: 768 RNQCSCHFQGVDYPPGD---SDIPSLGHCHCKDG 798
            ++C C F G  Y  G+   +       C C++G
Sbjct: 647 LHKCGCDFDGHYYTMGEFFWATANCTVQCLCEEG 680



 Score =  112 bits (279), Expect = 7e-24
 Identities = 104/403 (25%), Positives = 158/403 (39%), Gaps = 57/403 (14%)

Query: 811  CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLP 870
            CP    F  C        ++   TCE   L L       C  GC C +G    G  C   
Sbjct: 984  CPENSHFEEC--------ITCTETCET--LTLGPICVDSCSEGCQCDEGYALLGSQCVTR 1033

Query: 871  EECPCTWKGKE-----------------YFPGDQVMSPCHTCVC--------QRGSFQCT 905
             EC C ++G +                 Y  G      C T  C        + G + C 
Sbjct: 1034 SECGCNFEGHQLATNETFWVDLDCQIFCYCSGTDNRVHCETIPCKDDEYCMEEGGLYYCQ 1093

Query: 906  LHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLV------KSTSDVSFSVIVENVNCYS 959
                AS C   G  HY TFDG PFDF  +C + L        S S   F V  +N +   
Sbjct: 1094 ARTDAS-CIVSGYGHYLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNEDRDP 1152

Query: 960  SGMICRKFISINV-GNSLIV---FDDDSGNPSPESFLDDK---QEVHTWRVGFFTLVHFP 1012
            S  +  K + + V G S+++   +       S   +L  K    +++ +  GF  +V   
Sbjct: 1153 SLALWVKQVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVE-T 1211

Query: 1013 QEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWA 1072
               + +++D +T + +      Q    GLCG ++    +++  P  L  ++  EFG SW 
Sbjct: 1212 DFGLKVVYDWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWV 1271

Query: 1073 AVECPDTLDPRDMCVLNPLREPFAKKE--CSILLSE--VFEICHPVVDVTWFYSNCLTDT 1128
              +    +   D C      E F+K +  CS++ ++   F  CH  V+ T+FY NCL D+
Sbjct: 1272 KRDTFCQVGCGDRCPSCAKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDS 1331

Query: 1129 CGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1170
              C  GG  +  C+ +  YA  C   G+ V  WR    C   C
Sbjct: 1332 --CIDGGAVQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTC 1372



 Score = 84.3 bits (207), Expect = 2e-15
 Identities = 82/338 (24%), Positives = 128/338 (37%), Gaps = 27/338 (7%)

Query: 852  SGCACPQGLLRHGDACF----LPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLH 907
            +GC      LR G+  +       +C C     E +  +   SP   C  +   F C+  
Sbjct: 258  NGCTSRGQFLRRGEVFWDDLNCTVKCRCLDFNNEIYCQEASCSPYEVCEPKGKFFYCSAV 317

Query: 908  PCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVS----FSVIVENVNCYSSGMI 963
               STC  +G+ HY TFDG  F F G+C   L +     S    FSV  +N +   S + 
Sbjct: 318  E-TSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHRRGSAVS 376

Query: 964  CRKFISINV-GNSLIVFDDDSGNPSPESFLD------DKQEVHTWRVGFFTLVHFPQEHI 1016
              K +S+ V G  +++     G       +       D   V  ++ G  T V      +
Sbjct: 377  WVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQSGISTAVE-TDFGL 435

Query: 1017 TLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSW----A 1072
             + +D +    +     +     GLCGN++   +++   P+     +  + G SW    A
Sbjct: 436  LVTFDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHA 495

Query: 1073 AVECPD-TLDPRDMCVLNPLREPFAKKECSILLSEVFEI--CHPVVDVTWFYSNCLTDTC 1129
              +C    +D    C        F    C  L      +  C  VVD T F  +C+ D C
Sbjct: 496  DWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLC 555

Query: 1130 GCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLC 1166
                 G     C ++ AYA  C   G+ + DWRT   C
Sbjct: 556  SVRDNG--TLLCQAIQAYALVCQALGIPIGDWRTQTGC 591



 Score = 72.4 bits (176), Expect = 6e-12
 Identities = 92/403 (22%), Positives = 142/403 (35%), Gaps = 58/403 (14%)

Query: 811  CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLP 870
            CP+   +  C+    D       TC    L  S +   PC  GC C QG +     C   
Sbjct: 597  CPSFSHYSVCTSSCPD-------TCSD--LTASRNCATPCTEGCECNQGFVLSTSQCVPL 647

Query: 871  EECPCTWKGKEYFPGDQVMSPCHT---CVCQRGS-FQCTLHPCAS--------------- 911
             +C C + G  Y  G+   +  +    C+C+ G    C    C S               
Sbjct: 648  HKCGCDFDGHYYTMGEFFWATANCTVQCLCEEGGDVYCFNKTCGSGEVCAVEDGYQGCFP 707

Query: 912  ----TCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD-VSFSVIVENVNCYSSGMICRK 966
                 C    ++   TFDG  + F       L+K+  +   +  I  N     +G    +
Sbjct: 708  KRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERPEYLEIDINKKKPDAGPAWLR 767

Query: 967  FISINVGNSLIVFDDD-------SGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLL 1019
             + I V +  +            +G      F     ++  +R    T V   +  +T+ 
Sbjct: 768  GLRILVADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVE-SKGVVTVQ 826

Query: 1020 WDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVE---- 1075
            +     ++++    +     GLCG ++    +E   P      N   F  SW   E    
Sbjct: 827  YSDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTFEEICN 886

Query: 1076 --CPDTLDP--RDMCVLNPLREPFAKKECSIL---LSEVFEICHPVVDVTWFYSNCLTDT 1128
              C D L     D  +L   R   ++  C I+    +  F  CH VV+VT +Y  CL   
Sbjct: 887  GECGDLLKACNNDSELLKFYR---SRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRL 943

Query: 1129 CGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1170
              C  GG+    C SV+ YA  C    V V  WRT   CP +C
Sbjct: 944  --CQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLEC 984



 Score = 70.5 bits (171), Expect = 2e-11
 Identities = 70/286 (24%), Positives = 114/286 (39%), Gaps = 30/286 (10%)

Query: 2158 GLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSV 2217
            GL+ +  S T      GLCG  + +A+++  L +G      ++ A FL+SW     + + 
Sbjct: 831  GLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCT---DNLAVFLESWTTFEEICN- 886

Query: 2218 GQTRFRPDSCATTD--------CSPC--LRMVSNRTFSACHRFVPPESFCELWI----RD 2263
            G+      +C             S C  +   SN +F  CH  V   ++    +    + 
Sbjct: 887  GECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRLCQS 946

Query: 2264 TKYVQQPCVALTVYVAMCHKFHVCI-EWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDG 2322
                 + C ++  Y + C    V +  WR  D+CP  C  +S ++ C+T  E   TC+  
Sbjct: 947  GGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEECITCTE---TCETL 1003

Query: 2323 ILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLS 2382
             LGP+  + C    EGC C EG  L     + C+  ++C C +  G   A  ET+   L 
Sbjct: 1004 TLGPICVDSC---SEGCQCDEGYAL---LGSQCVTRSECGC-NFEGHQLATNETFWVDLD 1056

Query: 2383 GCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCL 2428
                  C   D  V  +   P    E C+  G +       D  C+
Sbjct: 1057 CQIFCYCSGTDNRVHCET-IPCKDDEYCMEEGGLYYCQARTDASCI 1101



 Score = 70.1 bits (170), Expect = 3e-11
 Identities = 79/361 (21%), Positives = 128/361 (35%), Gaps = 49/361 (13%)

Query: 850  CLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVM-SPC-HTCVC-QRGSFQCTL 906
            C+ GC C  G + +G +C LP  C C   GK Y P      S C   C C +R   QC  
Sbjct: 1402 CVEGCHCDAGYVLNGKSCILPHSCGCYSDGKYYEPKQLFWNSDCTRRCRCFRRNVIQCDP 1461

Query: 907  HPC-------------------ASTCTAYGDRHYRTFDGLPFDFVGACKVHL---VKSTS 944
              C                    S C A G   +RTFDG    F   C   L    +   
Sbjct: 1462 RQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANCAFVLSTICQKLP 1521

Query: 945  DVSFSVIVENVNCYSSGMICRKFISINVGNSLIVFDDD-----SGNPSPESFLDDKQEVH 999
            D+SF +I+      +  +     +   +    I+ +D      +G      F+       
Sbjct: 1522 DISFQLIINFDKWSAPNLTIISPVYFYINEEQILINDRNTVKVNGTQVNVPFITGLATKI 1581

Query: 1000 TWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENL 1059
                GF  +   P   I + ++    + +    + Q ++ GLCGNF+    ++  T    
Sbjct: 1582 YSSEGFLVIDTSPD--IQIYYNGFNVIKISISERLQNKVCGLCGNFNGDLTDDYVTLRGK 1639

Query: 1060 ELTNPQEFGSSW---------AAVECPDTLDPR--DMCVLNPLREPFAKKECSIL--LSE 1106
             + +      SW          A  C +    +   MC    +++      C  L  +  
Sbjct: 1640 PVVSSVVLAQSWKTNGMQKRPLAPSCNELQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKG 1699

Query: 1107 VFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGV-AVDWRTPRL 1165
             F+ C+ ++D   FY +C  D C   +       C S++AY   C   G+ + +W     
Sbjct: 1700 FFQPCYGLLDPLPFYESCYLDGCYSHKKFQ---LCGSLAAYGEACRSFGILSTEWIEKEN 1756

Query: 1166 C 1166
            C
Sbjct: 1757 C 1757



 Score = 68.2 bits (165), Expect = 1e-10
 Identities = 81/368 (22%), Positives = 138/368 (37%), Gaps = 44/368 (11%)

Query: 2098 LNMTHLAHQVTIDR-FNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHS 2156
            +++T   + + I R +   V V+ + ++ P+     +I      + ++  +D  ++ ++ 
Sbjct: 1161 VDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYD 1220

Query: 2157 -SGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLT 2215
                + +   ++ +   +GLCG  +G+  +DL +  G +     +   F  SW    +  
Sbjct: 1221 WKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNE---FGQSWVKRDTFC 1277

Query: 2216 SVGQTRFRPDSCATTDCSPCLRMVS-----NRTFSACHRFVPPESFCELWIRDTKY---- 2266
             VG     P        S   ++ S     N  FS CH  V P  F +  + D+      
Sbjct: 1278 QVGCGDRCPSCAKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGA 1337

Query: 2267 VQQPCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILG 2325
            VQ  C  L  Y + C    + +  WR    C   C  +S Y++CV+ C+P   C   I  
Sbjct: 1338 VQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQP--RCA-AIRL 1394

Query: 2326 PLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCC 2385
              D  H  V  EGC C  G +L+ +    CI    C C             WNS  +  C
Sbjct: 1395 KSDCSHYCV--EGCHCDAGYVLNGKS---CILPHSCGCYSDGKYYEPKQLFWNSDCTRRC 1449

Query: 2386 Q-----------HQCQAPDTIVPVD--LGCPSPRPESCL--------RFGEVALLLPTKD 2424
            +            QC++ +     +   GC S +   CL         F    L  P   
Sbjct: 1450 RCFRRNVIQCDPRQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANC 1509

Query: 2425 PCCLGTVC 2432
               L T+C
Sbjct: 1510 AFVLSTIC 1517



 Score = 53.9 bits (128), Expect = 2e-06
 Identities = 65/277 (23%), Positives = 101/277 (36%), Gaps = 43/277 (15%)

Query: 2174 GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCS 2233
            GLCG  + +  +D    DG       D     +SW+V  +        ++ DS    +C+
Sbjct: 459  GLCGNYNKNPLDDFLRPDGRPAMSVLDLG---ESWRVYHA-------DWKCDSGCVDNCT 508

Query: 2234 PCLRMVSNRTFSA---------------CHRFVPPESFCELWIRDTKYVQQP----CVAL 2274
             C        F +               C   V P +F    + D   V+      C A+
Sbjct: 509  QCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQAI 568

Query: 2275 TVYVAMCHKFHVCI-EWRRSDYC--PFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEH 2331
              Y  +C    + I +WR    C     C S S Y  C ++C  P TC D          
Sbjct: 569  QAYALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSSC--PDTCSDLTASRNCATP 626

Query: 2332 CQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQA 2391
            C    EGC C++G +L    ++ C+P  KC C D  G    +GE + ++ +   Q  C+ 
Sbjct: 627  CT---EGCECNQGFVL---STSQCVPLHKCGC-DFDGHYYTMGEFFWATANCTVQCLCEE 679

Query: 2392 PDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCL 2428
               +   +  C S   E C          P ++  CL
Sbjct: 680  GGDVYCFNKTCGS--GEVCAVEDGYQGCFPKRETVCL 714



 Score = 40.4 bits (93), Expect = 0.025
 Identities = 69/305 (22%), Positives = 111/305 (36%), Gaps = 50/305 (16%)

Query: 2047 FVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHL--- 2103
            F TFDG+ +       ++LS    ++  +         +    W    L +++  +    
Sbjct: 1495 FRTFDGAFLRFPANCAFVLSTICQKLPDISF----QLIINFDKWSAPNLTIISPVYFYIN 1550

Query: 2104 AHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVE 2163
              Q+ I+  N       Q   P ++    +I  +    +I T  DIQI +   +G  +++
Sbjct: 1551 EEQILINDRNTVKVNGTQVNVPFITGLATKIYSSEGFLVIDTSPDIQIYY---NGFNVIK 1607

Query: 2164 ASKTSKAQGH--GLCGICDGDAAND-LTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT 2220
             S + + Q    GLCG  +GD  +D +TL+   VV           SW+     T+  Q 
Sbjct: 1608 ISISERLQNKVCGLCGNFNGDLTDDYVTLRGKPVVSS----VVLAQSWK-----TNGMQK 1658

Query: 2221 RFRPDSCATTDCSP------------------CLRMVSNR-TFSACHRFVPPESFCELWI 2261
            R    SC     S                   CL++   +  F  C+  + P  F E   
Sbjct: 1659 RPLAPSCNELQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYESCY 1718

Query: 2262 RDTKYVQ---QPCVALTVYVAMCHKFHV-CIEWRRSDYCPFLCSSDSTYQACVTACEPPK 2317
             D  Y     Q C +L  Y   C  F +   EW   + C     S      CV A  P +
Sbjct: 1719 LDGCYSHKKFQLCGSLAAYGEACRSFGILSTEWIEKENC-----SGVVEDPCVGADCPNR 1773

Query: 2318 TCQDG 2322
            TC+ G
Sbjct: 1774 TCELG 1778


>gi|16554449 zonadhesin isoform 3 [Homo sapiens]
          Length = 2812

 Score =  230 bits (586), Expect = 2e-59
 Identities = 201/752 (26%), Positives = 299/752 (39%), Gaps = 77/752 (10%)

Query: 79   CRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS----FSIQVHNDPQCGSSPYTCS 134
            C  +G  H  TFDG ++   GK +Y L    +P G S    F +   N+ Q G    +C 
Sbjct: 1156 CLVYGDPHYVTFDGRHFGFMGKCTYILA---QPCGNSTDPFFRVTAKNEEQ-GQEGVSCL 1211

Query: 135  RAVSLFFVGEQEIHLAK--EVTHGGMRVQLPHVMGSARLQQLAG-YVIVRHQSAFTLAWD 191
              V +  + E  + L K      GG +V LP +         +G +V ++ +    + WD
Sbjct: 1212 SKVYVT-LPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWD 1270

Query: 192  GASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPG 251
            G   +Y+ +S    G   GLCGN + +  +D +   G    D  E  +SWQ         
Sbjct: 1271 GDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQEC 1330

Query: 252  PTTSSLPRPPCLQQNPGTMQGVYEQCEALL--RPPFDACHAYVSPLPFTASCTSDLCQSM 309
                 +  P C      +M G    C  L+    PF+ C  +V    F  SC  D+C   
Sbjct: 1331 QKYQVVNSPSCDSSLQSSMSGP-GFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQ 1389

Query: 310  GDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRA 369
            G     C  ++     C  AG  ++ WR +   C + C   +  Y+ C   CP +CH   
Sbjct: 1390 GLQHLLCTHMSTMTTTCQDAGHAVKPWR-EPHFCPMACPPNS-KYSLCAKPCPDTCHSGF 1447

Query: 370  SCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSV-------VKEDC-N 421
            S +     CV+ C C  G +     C+  ++C C     L+P GS         K  C  
Sbjct: 1448 SGMFCSDRCVEACECNPGFVLSGLECIPRSQCGC-----LHPAGSYFKVGERWYKPGCKE 1502

Query: 422  TCTCTSGK------WECST--------------AVCPAECSVTGDIHFTTFDGRRYTFPA 461
             C C S        W C                A   A C+ +GD H+ TFDG  + F  
Sbjct: 1503 LCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMG 1562

Query: 462  TCQYILAK---SRSSGT-FTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDV 517
            TC Y+L +   SRS  + F V+  N   G   + + +++V V +       ++L +   V
Sbjct: 1563 TCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFD---LSISLLRGCKV 1619

Query: 518  LLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVG 577
            +L      +P +        RLSS  + + TN G++V YD   L + + V   +     G
Sbjct: 1620 MLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHL-VEVTVPSSYGGQLCG 1678

Query: 578  LCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSP---LVSGSPLDPCDVHLQAAS 634
            LCG +N N+ DD L P           G +WK   +  P   LV G P   C  +  A +
Sbjct: 1679 LCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKP-SSCQENSMADA 1737

Query: 635  YSVQACSVLTGEM--FAPCSAFLSPVPYFEQCRRDAC--RCGQPCLCATLAHYAHLCRRH 690
            ++ + C++L      F+ C   + P   F  C    C  +     LC +L  YA LC + 
Sbjct: 1738 WN-KNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQA 1796

Query: 691  GLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGC 750
            G    +R R   C + C     YSPC +PC  TC  + +P  C            C E C
Sbjct: 1797 GQAPAWRNR-TFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCP-------KALPCAESC 1848

Query: 751  ACPPDTYLDTQADLCVPRNQCSCHFQGVDYPP 782
             C     L   +  CVP  QC C      Y P
Sbjct: 1849 ECQKGHILSGTS--CVPLGQCGCTDPAGSYHP 1878



 Score =  224 bits (570), Expect = 1e-57
 Identities = 218/885 (24%), Positives = 348/885 (39%), Gaps = 127/885 (14%)

Query: 25   ERRLHRAKCAPSYLFS---CFNGGEC--VHPA-----------------FCDCRRFNATG 62
            +R +   +C P ++ S   C    +C  +HPA                  C C   N   
Sbjct: 1454 DRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRI- 1512

Query: 63   PRCQM--------------VYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGR 108
             RCQ               +Y    +  + C A G  H  TFDG  ++  G  +Y L   
Sbjct: 1513 -RCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRP 1571

Query: 109  HEPEGQS--FSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAK--EVTHGGMRVQLPH 164
                 Q   F +   N+ + G    +  +AV +  V +  I L +  +V   G RV LP 
Sbjct: 1572 CWSRSQDSYFVVSATNENRGGILEVSYIKAVHVT-VFDLSISLLRGCKVMLNGHRVALPV 1630

Query: 165  VMGSAR--LQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDD 222
             +   R  ++  +  V++       + +DG+  V + +     G   GLCGN N +  DD
Sbjct: 1631 WLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDD 1690

Query: 223  LVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQ-CEALL 281
             +    KL  D ++   +W+    ++P         +P   Q+N  +M   + + C  L+
Sbjct: 1691 NLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGG--KPSSCQEN--SMADAWNKNCAILI 1746

Query: 282  RP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQ 339
             P  PF  CH  V P    ASC    C + GD    CR+L  YA  CAQAG+    WR +
Sbjct: 1747 NPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQ-APAWRNR 1805

Query: 340  LRQCTVHCKEKAFTYNECIACCPASC----HPRASCVDSEIACVDGCYCPNGLIFEDGGC 395
               C + C   + +Y+ C + CP +C    +PR  C    + C + C C  G I     C
Sbjct: 1806 -TFCPMRCPPGS-SYSPCSSPCPDTCSSINNPR-DC-PKALPCAESCECQKGHILSGTSC 1861

Query: 396  VAPAECPC-EFHGTLYPPGS--VVKEDC-NTCTCT-SGKWECSTAVCPAE---------- 440
            V   +C C +  G+ +P G     +  C   CTC+      C  + C             
Sbjct: 1862 VPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLL 1921

Query: 441  ---------CSVTGDIHFTTFDGRRYTFPATCQYILAK----SRSSGTFTVTLQNAPCGL 487
                     C + G+ H+ +FDG  ++ P  C  +L K    + +   F ++ ++     
Sbjct: 1922 RCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEG 1981

Query: 488  NQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVR 547
              +   +  V + ++     QVTL +   VL+  +   +P  +       + SS++  V 
Sbjct: 1982 GTEAFRLHEVYIDIYD---AQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVN 2038

Query: 548  TNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNS 607
              +GV+V +D   L L +++   +     G+CG FN   +D+ + P     ++   F NS
Sbjct: 2039 IKIGVQVKFDGNHL-LEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNS 2097

Query: 608  WKTLS---ACSPLVSGSPLDPCD-----------VHLQAASYSVQACSVLTGEMFAPCSA 653
            WK      +C  L+      P +             L+ A    +A   L   ++A C++
Sbjct: 2098 WKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEA--ALRAPVWAQCAS 2155

Query: 654  FLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASK 711
             +   P+   C    C  G     LC  L  +   C+  GL          C L C A  
Sbjct: 2156 RIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYS 2215

Query: 712  EYSPCVAPCGRTCQDLASPEACGVDGGDDLSR--DECVEGCACPPDTYLDTQADLCVPRN 769
             Y+ C+  C  +C DL        DG  + ++    C EGC C P   L    D CVPR+
Sbjct: 2216 SYTNCLPSCSPSCWDL--------DGRCEGAKVPSACAEGCICQPGYVL--SEDKCVPRS 2265

Query: 770  QCSC-HFQGVDYPPGDSDIPS--LGHCHCKDGVMSC-DSRAPAAA 810
            QC C    G   P G S + S     C C  G + C D R P+ +
Sbjct: 2266 QCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQCGDFRCPSGS 2310



 Score =  179 bits (454), Expect = 3e-44
 Identities = 144/476 (30%), Positives = 196/476 (41%), Gaps = 63/476 (13%)

Query: 335  GWRTQLRQCTVHCKEKAFTYNECIACCPASCH-PRASCVDSEIACVDGCYCPNGLIFEDG 393
            G  T  R  T  C   A  Y  C   CPASC  PR SC      C +GC C  G +F D 
Sbjct: 1032 GTTTTSRSSTERCPPNA-RYESC--ACPASCKSPRPSCGP---LCREGCVCNPGFLFSDN 1085

Query: 394  GCVAPAECPCEFHGTLYPPGSV-----VKEDCN------------------TCTCTSGKW 430
             C+  + C C ++   Y PG+        E C                    C   +G++
Sbjct: 1086 HCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQY 1145

Query: 431  ECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGT---FTVTLQNAPCGL 487
             C      A C V GD H+ TFDGR + F   C YILA+   + T   F VT +N   G 
Sbjct: 1146 GCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQG- 1204

Query: 488  NQDG-ACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRV 546
             Q+G +C+  V V L   P   VTL +    L+  Q   +P        +   S  F+ +
Sbjct: 1205 -QEGVSCLSKVYVTL---PESTVTLLKGRRTLVGGQQVTLPAIPSKGVFL-GASGRFVEL 1259

Query: 547  RTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGN 606
            +T  G+RV +D +  +LY+ V   +     GLCG ++GN+ +D L   G P    +  GN
Sbjct: 1260 QTEFGLRVRWDGD-QQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGN 1318

Query: 607  SWKT----LSACSPL-VSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVP 659
            SW+T       C    V  SP   CD  LQ++      C  L  T   F  C   +    
Sbjct: 1319 SWQTDQDEDQECQKYQVVNSP--SCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAAS 1376

Query: 660  YFEQCRRDAC--RCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCV 717
            +F+ C  D C  +  Q  LC  ++     C+  G  V        C ++C  + +YS C 
Sbjct: 1377 FFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCA 1436

Query: 718  APCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSC 773
             PC  TC    S   C          D CVE C C P   L      C+PR+QC C
Sbjct: 1437 KPCPDTCHSGFSGMFCS---------DRCVEACECNPGFVLSGLE--CIPRSQCGC 1481



 Score =  164 bits (414), Expect = 2e-39
 Identities = 201/850 (23%), Positives = 306/850 (36%), Gaps = 170/850 (20%)

Query: 78   ICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS--FSIQV-HNDPQCGSSPYTCS 134
            +C+  G+ H  +FDG  + +    +  LV    P      F I   H   + G+  +   
Sbjct: 1930 VCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLH 1989

Query: 135  RAVSLFFVGEQEIHLAKEVTHGGMRVQLPHV--MGSARLQQLAGYVIVRHQSAFTLAWDG 192
                  +  +  +     V     +V LP +  +    ++  + Y IV  +    + +DG
Sbjct: 1990 EVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDG 2049

Query: 193  ASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGP 252
               + I++     G   G+CGN N + +D+L+  S ++ +   EFV+SW+++  +    P
Sbjct: 2050 NHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDID----P 2105

Query: 253  TTSSL-----PRPPCLQQNPG------TMQGVYEQCEALLRPPFDA-CHAYVSPLPFTAS 300
            +  SL       P   Q+NP        ++   E+CEA LR P  A C + +   PF   
Sbjct: 2106 SCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVD 2165

Query: 301  CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 360
            C + LC+  G     C+AL  +   C   G     WR     C + C   + +Y  C+  
Sbjct: 2166 CANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNS-SFCPLECPAYS-SYTNCLPS 2223

Query: 361  CPASCHPR-ASCVDSEI--ACVDGCYCPNGLIFEDGGCVAPAECPC-EFHGTLYPPG-SV 415
            C  SC      C  +++  AC +GC C  G +  +  CV  ++C C + HG   P G S 
Sbjct: 2224 CSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSW 2283

Query: 416  VKEDCNT-CTCTSGKWECSTAVCPA---------------------ECSVTGDIHFTTFD 453
            V   C   C CT G  +C    CP+                     +CSV GD  + TFD
Sbjct: 2284 VSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFD 2343

Query: 454  GRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTL-- 511
            G  Y       Y+L K         T+   P G+  +   V+  + +    PR  + L  
Sbjct: 2344 GFSYRLQGRMTYVLIK---------TVDVLPEGV--EPLLVEGRNKM--DPPRSSIFLQE 2390

Query: 512  -----------TQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREG 560
                        QAG  L+ +  K+  PY                 R N  +RV     G
Sbjct: 2391 VITTVYGYKVQLQAGLELVVNNQKMAVPY-----------------RPNEHLRVTL--WG 2431

Query: 561  LRLYLQVDQRWVED------------------TVGLCGTFNGNTQDDFLSPVGVPESTPQ 602
             RLYL  D   V                      GLCG ++ N ++D + P G       
Sbjct: 2432 QRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLN 2491

Query: 603  LFGNSWKTLS-------------------ACSPLVSGSPLDPCDVHLQAASYSVQACSVL 643
             FGNSW+  +                   A   L +G  +  C    Q AS S QAC VL
Sbjct: 2492 TFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPE-QLASNSTQACRVL 2550

Query: 644  TGEM--FAPCSAFLSPVPYFEQCRRDACRCGQP-----CLCATLAHYAHLCRRH------ 690
                  FA C   ++P P+ E C  D C    P       C  L+ +    R H      
Sbjct: 2551 ADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGHGVSSRYHISELYD 2610

Query: 691  -------------GLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDG 737
                         GL    R RL      C       P +A CG T   +          
Sbjct: 2611 TLPSILCQPGRPRGLRGPLRGRLRQHPRLC-LQWHPEPPLADCGCTSNGIY------YQL 2663

Query: 738  GDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSC--HFQGV--DYPPGDSDIPSLGHC 793
            G     ++C + C C     L  +   C     C+   H QG   + P   +   + G C
Sbjct: 2664 GSSFLTEDCSQRCTCASSRILLCEPFSCRAGEVCTLGNHTQGCFPESPCLQNPCQNDGQC 2723

Query: 794  HCKDGVMSCD 803
              +    +C+
Sbjct: 2724 REQGATFTCE 2733



 Score =  150 bits (379), Expect = 2e-35
 Identities = 226/1035 (21%), Positives = 364/1035 (35%), Gaps = 165/1035 (15%)

Query: 1429 PRTPTHRPALTPAAPLTTALNP-PVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTES 1487
            P  P   P  +     TT L   P  +T++P VS      T ++P      + P  PTE 
Sbjct: 540  PELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPT--VPKEKPTIPTEK 597

Query: 1488 PASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSP 1547
            P       ++ +      S    +  + PT       + + + T+    S   T+S+  P
Sbjct: 598  PTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTI---PSEKPTISTEKP 654

Query: 1548 PAPRFPLMTKAVTVRGHGSLPVRTTPLQPSLTASPSSRPVASPGAISRSPTSSGSHKAVL 1607
              P     T           PV  T  +PS+     S P   P  IS   T   + K  +
Sbjct: 655  TVPTEEPTTPTEETTTSMEEPVIPTE-KPSIPTEKPSIPTEKP-TISMEETIISTEKPTI 712

Query: 1608 TPAVTKV-ISRTGVPQPTQAQSASSPSTPL------TVAGTAAEQVPVSPLATRSL---E 1657
            +P    +   +  +P      S   P+TP       T   T + + P +P    ++   +
Sbjct: 713  SPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEK 772

Query: 1658 IVLSTEKGEAGHSQPMGSPASPQPHPLPSA--PPRPAQHTTMATRSPALPPETPAAASLS 1715
            + + TEK       P   P  P   P  S   P  P + TT++T  P++P E P   +  
Sbjct: 773  LTIPTEKPTI----PTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEE 828

Query: 1716 TATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQ 1775
            T T         S+E T  S          ++P+ K      ++T  P        + P+
Sbjct: 829  TTT---------SVEETTIST------EKLTIPMEK----PTISTEKPTIPTEKPTISPE 869

Query: 1776 ATTLPAQTLS-----PVLPF--TPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLP 1828
              T+P + L+     P +P   T  +  +   PT   P  +   P   +    PT   +P
Sbjct: 870  KLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTE-KPTISPEKP--TISTEKPT---IP 923

Query: 1829 VAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGSAEGGPTELTPATSHPLTPLVAEP 1888
              + T      +P + TT    I ++++++PT         P +LT  T  P    ++  
Sbjct: 924  TEKPT------IPTEETT----ISTEKLTIPTE---KPTISPEKLTIPTEKPT---ISTE 967

Query: 1889 EGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLAEAHGTSAGPHLAAEPVDEATTE 1948
            +       L +PT          T P + +  L P     H +     LAA         
Sbjct: 968  KPTIPTEKLTIPTEKPTIPTEKPTIPTEKLTALRPP----HPSPTATGLAA-----LVMS 1018

Query: 1949 PSGRSAPALSIVEGLAEALATTTEA-----------------NTSTTCVPIAEQDCV--- 1988
            P   S P  S++ G      ++TE                  +   +C P+  + CV   
Sbjct: 1019 PHAPSTPMTSVILGTTTTSRSSTERCPPNARYESCACPASCKSPRPSCGPLCREGCVCNP 1078

Query: 1989 -----RHICLEG----------------QLIRVNQSQHC---PQGAAP---PRCGILGLA 2021
                  + C++                 +    N ++HC   P         +CG   + 
Sbjct: 1079 GFLFSDNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVC 1138

Query: 2022 VRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQ----SPDEMLTVHV 2077
                G   C  +     C ++ D  +VTFDG H     +  YIL+Q    S D    V  
Sbjct: 1139 QLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTA 1198

Query: 2078 LDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDT 2137
             + +    G       CL  + +T     VT+ +  R +    Q   P +   G  +  +
Sbjct: 1199 KNEEQGQEG-----VSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGAS 1253

Query: 2138 GHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGG 2197
            G    + T   ++++W      + V  S T   +  GLCG  DG++ ND    DGS  G 
Sbjct: 1254 GRFVELQTEFGLRVRW-DGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGD 1312

Query: 2198 AEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSP---------CLRMV-SNRTFSAC 2247
             E+     +SWQ         Q +++  +  + D S          C R+V ++  F  C
Sbjct: 1313 KEELG---NSWQTDQDEDQECQ-KYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETC 1368

Query: 2248 HRFVPPESFCELWIRDTKYVQ----QPCVALTVYVAMCHKF-HVCIEWRRSDYCPFLCSS 2302
               V   SF +  + D    Q      C  ++     C    H    WR   +CP  C  
Sbjct: 1369 LLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPP 1428

Query: 2303 DSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCA 2362
            +S Y  C   C  P TC  G  G    + C    E C C+ G +L       CIP ++C 
Sbjct: 1429 NSKYSLCAKPC--PDTCHSGFSGMFCSDRCV---EACECNPGFVL---SGLECIPRSQCG 1480

Query: 2363 CTDSMGVPRALGETW 2377
            C    G    +GE W
Sbjct: 1481 CLHPAGSYFKVGERW 1495



 Score =  108 bits (269), Expect = 1e-22
 Identities = 102/406 (25%), Positives = 158/406 (38%), Gaps = 63/406 (15%)

Query: 810  ACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFL 869
            ACP    +  C+    D       TC      +  S R  C+  C C  G +  G  C  
Sbjct: 1425 ACPPNSKYSLCAKPCPD-------TCHSGFSGMFCSDR--CVEACECNPGFVLSGLECIP 1475

Query: 870  PEECPCTWKGKEYFP-GDQVMSP-C-HTCVCQRGS-FQCTLHPC---------------- 909
              +C C      YF  G++   P C   CVC+  +  +C    C                
Sbjct: 1476 RSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCH 1535

Query: 910  ---ASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKS----TSDVSFSVIVENVN------ 956
               A+TCTA GD HY TFDG    F+G C   L +     + D  F V   N N      
Sbjct: 1536 AQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILE 1595

Query: 957  -CYSSGMICRKF-ISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQE 1014
              Y   +    F +SI++     V  +      P      +  +   R+    ++ +   
Sbjct: 1596 VSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTI---RLSSNLVLLYTNF 1652

Query: 1015 HITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAV 1074
             + + +D    V V     + GQL GLCGN++  ++++   P+     +  + G++W   
Sbjct: 1653 GLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAW--- 1709

Query: 1075 ECPDTLDPR--------DMCVLNPLREPFAKKECSILLSEV--FEICHPVVDVTWFYSNC 1124
            + P++ +P           C  N + + +  K C+IL++    F  CH VV     +++C
Sbjct: 1710 KLPESSEPGCFLVGGKPSSCQENSMADAW-NKNCAILINPQGPFSQCHQVVPPQSSFASC 1768

Query: 1125 LTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDC 1170
            +   CG    GD    C S+ AYA  C Q G A  WR    CP  C
Sbjct: 1769 VHGQCGTK--GDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRC 1812



 Score =  107 bits (268), Expect = 1e-22
 Identities = 100/406 (24%), Positives = 147/406 (36%), Gaps = 55/406 (13%)

Query: 804  SRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRH 863
            SR+    CP    + +C+             C     +   S    C  GC C  G L  
Sbjct: 1037 SRSSTERCPPNARYESCA-------------CPASCKSPRPSCGPLCREGCVCNPGFLFS 1083

Query: 864  GDACFLPEECPCTWKGKEYFPGDQVMSP--------------------CHT-CVCQRGSF 902
             + C     C C +    Y PG +  SP                    C T  VCQ  + 
Sbjct: 1084 DNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNG 1143

Query: 903  QCTLHPCA--STCTAYGDRHYRTFDGLPFDFVGACKVHLVK---STSDVSFSVIVENVNC 957
            Q   HP A  +TC  YGD HY TFDG  F F+G C   L +   +++D  F V  +N   
Sbjct: 1144 QYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQ 1203

Query: 958  YSSGMICRKFISINVGNSLIVFDDDS----GNPSPESFLDDKQEVHTWRVGFFTLVHFPQ 1013
               G+ C   + + +  S +          G           + V     G F  +   +
Sbjct: 1204 GQEGVSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQ-TE 1262

Query: 1014 EHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAA 1073
              + + WD    ++V     + G+L GLCGN+D  + N+    +     + +E G+SW  
Sbjct: 1263 FGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQT 1322

Query: 1074 VECPDTLDPRDMCVLNPLREPFAKKE------CSILLSE--VFEICHPVVDVTWFYSNCL 1125
             +  D    +   V +P  +   +        C  L+     FE C   V    F+ +C+
Sbjct: 1323 DQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCM 1382

Query: 1126 TDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1170
             D CG    G     C  +S     C   G AV  WR P  CP  C
Sbjct: 1383 LDMCGFQ--GLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMAC 1426



 Score = 93.2 bits (230), Expect = 3e-18
 Identities = 93/378 (24%), Positives = 147/378 (38%), Gaps = 69/378 (18%)

Query: 2036 ACRCSIFPDLSFVTFDGSHVALFKEAIYIL-----SQSPDEMLTVHVLDCKSANLGHLNW 2090
            A  C+   D  ++TFDG+         Y+L     S+S D    V   +     +  +++
Sbjct: 1539 AATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSY 1598

Query: 2091 PPF---------------CLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIE 2135
                              C VMLN     H+V +            PVW    R   R+ 
Sbjct: 1599 IKAVHVTVFDLSISLLRGCKVMLN----GHRVAL------------PVWLAQGRVTIRL- 1641

Query: 2136 DTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLKDGS 2193
             + ++ ++ T   +Q+++    G  +VE +  S   G   GLCG  + ++ +D    D  
Sbjct: 1642 -SSNLVLLYTNFGLQVRY---DGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRK 1697

Query: 2194 VVGGAEDPAPFLDSWQVP-SSLTSVGQTRFRPDSCATTDCSP-----CLRMVSNR-TFSA 2246
            + G   D      +W++P SS         +P SC     +      C  +++ +  FS 
Sbjct: 1698 LAG---DSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQ 1754

Query: 2247 CHRFVPPESFCELWIR-------DTKYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFL 2299
            CH+ VPP+S     +        DT  +   C +L  Y ++C +      WR   +CP  
Sbjct: 1755 CHQVVPPQSSFASCVHGQCGTKGDTTAL---CRSLQAYASLCAQAGQAPAWRNRTFCPMR 1811

Query: 2300 CSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEA 2359
            C   S+Y  C + C  P TC   I  P D        E C C +G IL       C+P  
Sbjct: 1812 CPPGSSYSPCSSPC--PDTC-SSINNPRDCPKALPCAESCECQKGHIL---SGTSCVPLG 1865

Query: 2360 KCACTDSMGVPRALGETW 2377
            +C CTD  G    +GE W
Sbjct: 1866 QCGCTDPAGSYHPVGERW 1883



 Score = 81.3 bits (199), Expect = 1e-14
 Identities = 105/477 (22%), Positives = 174/477 (36%), Gaps = 44/477 (9%)

Query: 1393 EPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPV 1452
            +P V +   ++  E     +  PT   E+P +S E P  P+ +P + P+   T     P 
Sbjct: 569  KPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNM-PSEKPTIPSEKPT 627

Query: 1453 TATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPA--SKGVTASLLAIPHTPESSSLP 1510
              TE+P +     + T+       +++ P  PTE P   ++  T S+       E  S+P
Sbjct: 628  ILTEKPTIP--SEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIP 685

Query: 1511 -----VALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLM-TKAVTVRGH 1564
                 +  + PT  M    + T + T I    P I     + P  +  +   K  T    
Sbjct: 686  TEKPSIPTEKPTISMEETIISTEKPT-ISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEK 744

Query: 1565 GSLPVRTTPLQPSLTASPSSRPVASPGAI---SRSPTSSGSHKAVLTPAVTKVISRTGVP 1621
             ++P     + P    +P+ +P  SP  +   +  PT       + T   T        P
Sbjct: 745  PTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTP 804

Query: 1622 QPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQ- 1680
                  S   PS P+         +P     T   E  +STEK      +P  S   P  
Sbjct: 805  TEETTISTEKPSIPM-----EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTI 859

Query: 1681 PHPLPSAPPR----PAQHTTMATRSPALPPE--TPAAASLSTATDGLAATPFMSLESTRP 1734
            P   P+  P     P +  T+ T  P +P E  T +   L+  T+    +P     ST  
Sbjct: 860  PTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEK 919

Query: 1735 SQLLSGLP----PDTSLPLAK--VGTSAPVATP--------GPKASVITTPLQPQATTLP 1780
              + +  P     +T++   K  + T  P  +P         P  S     +  +  T+P
Sbjct: 920  PTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIP 979

Query: 1781 AQ--TLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTAS 1835
             +  T+    P  P     A  P H +P A G A  L++    P++ +  V  GT +
Sbjct: 980  TEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLA-ALVMSPHAPSTPMTSVILGTTT 1035



 Score = 76.6 bits (187), Expect = 3e-13
 Identities = 87/428 (20%), Positives = 153/428 (35%), Gaps = 88/428 (20%)

Query: 811  CPAGQVFVNCSDLHTDL--ELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACF 868
            CP G  +  CS    D    ++  R C + L         PC   C C +G +  G +C 
Sbjct: 1812 CPPGSSYSPCSSPCPDTCSSINNPRDCPKAL---------PCAESCECQKGHILSGTSCV 1862

Query: 869  LPEECPCTWKGKEYFPGDQVMSPCHTCV----CQRGS----FQCTLHP------------ 908
               +C CT     Y P  +     +TC     C   +    FQ T  P            
Sbjct: 1863 PLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLR 1922

Query: 909  CAST----CTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDV------------------ 946
            C ++    C   G+ HY +FDG       AC + LVK                       
Sbjct: 1923 CRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGG 1982

Query: 947  --SFSVIVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVG 1004
              +F +    ++ Y + +  +K   + + +  +     S  P           +   ++G
Sbjct: 1983 TEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIG 2042

Query: 1005 FFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNP 1064
                       + + +D    + ++    + G++ G+CGNF+ +  +E+  P +    + 
Sbjct: 2043 -----------VQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSD 2091

Query: 1065 QEFGSSWAAVE----CPDTL------------DPRDMCVLNPLREPFAKKEC-SILLSEV 1107
             EF +SW   +    C   L            +P   C    LR   A+++C + L + V
Sbjct: 2092 SEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRR--AREKCEAALRAPV 2149

Query: 1108 FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVD-WRTPRLC 1166
            +  C   +D+T F  +C      C  GG  +  C ++ A+   C   G+    WR    C
Sbjct: 2150 WAQCASRIDLTPFLVDCANTL--CEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFC 2207

Query: 1167 PYDCDFFN 1174
            P +C  ++
Sbjct: 2208 PLECPAYS 2215



 Score = 76.3 bits (186), Expect = 4e-13
 Identities = 77/322 (23%), Positives = 129/322 (40%), Gaps = 35/322 (10%)

Query: 2106 QVTIDRFNRKVTVDLQPVWPPVSRY-GFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEA 2164
            QVT+ + +R +    Q   P +S+  G  ++ +    ++     +Q+++   + L+ +E 
Sbjct: 1999 QVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKF-DGNHLLEIEI 2057

Query: 2165 SKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQV----PSSLTSVGQT 2220
              T   +  G+CG  + +  ++L +    V   A   + F++SW+     PS  + +   
Sbjct: 2058 PTTYYGKVCGMCGNFNDEEEDELMMPSDEV---ANSDSEFVNSWKDKDIDPSCQSLLVDE 2114

Query: 2221 RFRPDSCATTDCSPCLRMVSNRTFSACHRFV--PPESFCELWIRDTKYV----------- 2267
            +  P          C      R    C   +  P  + C   I  T ++           
Sbjct: 2115 QQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFG 2174

Query: 2268 ---QQPCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDG- 2322
               Q  C AL  + A C    +    WR S +CP  C + S+Y  C+ +C P     DG 
Sbjct: 2175 GLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGR 2234

Query: 2323 ILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLS 2382
              G   P  C    EGC+C  G +L       C+P ++C C D+ G    LG++W S  S
Sbjct: 2235 CEGAKVPSAC---AEGCICQPGYVLSEDK---CVPRSQCGCKDAHGGSIPLGKSWVS--S 2286

Query: 2383 GCCQHQCQAPDTIVPVDLGCPS 2404
            GC +        I   D  CPS
Sbjct: 2287 GCTEKCVCTGGAIQCGDFRCPS 2308



 Score = 75.9 bits (185), Expect = 5e-13
 Identities = 109/470 (23%), Positives = 168/470 (35%), Gaps = 91/470 (19%)

Query: 1363 PRVEGCVPVCPTPQVLDEVTQRCVYLEDCVEPAVW--VPTEALGNETLPPSQGL------ 1414
            P +    P  PT +      +    +E+ V P     +PTE     T  P+  +      
Sbjct: 647  PTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIIS 706

Query: 1415 ---PTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTTLQQ 1471
               PT S E+P +  E P  PT +  ++P  P TT    P   TE+P +SP         
Sbjct: 707  TEKPTISPEKPTIPTEKPTIPTEKSTISPEKP-TTPTEKPTIPTEKPTISP--------- 756

Query: 1472 PLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQT-PTPGMVSGAMETTRV 1530
                   + P  PTE P    ++   L IP   E  ++P    T PT        E T  
Sbjct: 757  -------EKPTTPTEKPT---ISPEKLTIP--TEKPTIPTEKPTIPTEKPTISTEEPTTP 804

Query: 1531 TVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRTTPLQPSLTASPSSRPVASP 1590
            T         T+S+  P  P    M K        +  V  T +       P  +P    
Sbjct: 805  T------EETTISTEKPSIP----MEKPTLPTEETTTSVEETTISTEKLTIPMEKP---- 850

Query: 1591 GAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTAAEQVPVSP 1650
              IS    +  + K  ++P                 +  + P+  LT+  T    +P+  
Sbjct: 851  -TISTEKPTIPTEKPTISP-----------------EKLTIPTEKLTIP-TEKPTIPIEE 891

Query: 1651 LATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPR-PAQHTTMATRSPALPPETP 1709
                + ++ + TEK      +P  S   P    +P+  P  P + TT++T    +P E P
Sbjct: 892  TTISTEKLTIPTEKPTISPEKPTISTEKP---TIPTEKPTIPTEETTISTEKLTIPTEKP 948

Query: 1710 AAA--SLSTATDGLAATPFMSLES-TRPSQLLSGLPPDTSLPLAKVGTSAPVATPGPKAS 1766
              +   L+  T+     P +S E  T P++ L+      ++P  K         P  K +
Sbjct: 949  TISPEKLTIPTE----KPTISTEKPTIPTEKLTIPTEKPTIPTEK------PTIPTEKLT 998

Query: 1767 VITTP-LQPQATTLPAQTLSPVLPFTP------AAMTQAHPPTHIAPPAA 1809
             +  P   P AT L A  +SP  P TP         T +   T   PP A
Sbjct: 999  ALRPPHPSPTATGLAALVMSPHAPSTPMTSVILGTTTTSRSSTERCPPNA 1048



 Score = 75.1 bits (183), Expect = 9e-13
 Identities = 93/442 (21%), Positives = 152/442 (34%), Gaps = 86/442 (19%)

Query: 61   TGPRCQMVY-----NAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHE--PEG 113
            +G  CQ+       N   ++   C  +G     TFDG  Y L G+ +Y L+   +  PEG
Sbjct: 2308 SGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEG 2367

Query: 114  -QSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQ 172
             +   ++  N      S       ++  +  + ++    E+     ++ +P+        
Sbjct: 2368 VEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRV 2427

Query: 173  QLAG---YVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGK 229
             L G   Y++   +    +++ G     I +     G   GLCGN + + K+D++  SG 
Sbjct: 2428 TLWGQRLYLVTDFE--LVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGA 2485

Query: 230  LTDDVVEFVHSWQEQAPNQPPGPTTSSLPRP-PCLQQNPGTMQGV--------------- 273
            LT ++  F +SW+ +  +          PR  P  ++  G   G+               
Sbjct: 2486 LTQNLNTFGNSWEVKTED-----ALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLA 2540

Query: 274  ---YEQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMG---DVATWCRALAEYA-- 323
                + C  L  P  PF ACH  V+P PF   C  DLC +          C+ L+ +   
Sbjct: 2541 SNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGHGVS 2600

Query: 324  -------------RACAQAGRP--LQG---------------WRTQLRQCTVHCKEKAFT 353
                             Q GRP  L+G               W  +       C      
Sbjct: 2601 SRYHISELYDTLPSILCQPGRPRGLRGPLRGRLRQHPRLCLQWHPEPPLADCGCTSNGIY 2660

Query: 354  YNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDG----GCVAPAEC---PCEFH 406
            Y    +     C  R +C  S I   +   C  G +   G    GC   + C   PC+  
Sbjct: 2661 YQLGSSFLTEDCSQRCTCASSRILLCEPFSCRAGEVCTLGNHTQGCFPESPCLQNPCQND 2720

Query: 407  GTLYPPGSVVKEDCNTCTCTSG 428
            G     G+       TC C  G
Sbjct: 2721 GQCREQGATF-----TCECEVG 2737



 Score = 70.9 bits (172), Expect = 2e-11
 Identities = 90/382 (23%), Positives = 129/382 (33%), Gaps = 77/382 (20%)

Query: 811  CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLP 870
            CPA   + NC    +      +  CE             C  GC C  G +   D C   
Sbjct: 2211 CPAYSSYTNCLPSCSPSCWDLDGRCE------GAKVPSACAEGCICQPGYVLSEDKCVPR 2264

Query: 871  EECPC--TWKGKEYFPGDQVMSPC-HTCVCQRGSFQCTLHPCAS---------------- 911
             +C C     G        V S C   CVC  G+ QC    C S                
Sbjct: 2265 SQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCV 2324

Query: 912  -----TCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSV---IVENVNCYS---S 960
                  C+ YGD  Y TFDG  +   G     L+K+   +   V   +VE  N      S
Sbjct: 2325 SDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRS 2384

Query: 961  GMICRKFIS--------INVGNSLIVFDDDSGNP-SPESFLDDKQEVHTWRVGFFTLVHF 1011
             +  ++ I+        +  G  L+V +     P  P   L     V  W    + +  F
Sbjct: 2385 SIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHL----RVTLWGQRLYLVTDF 2440

Query: 1012 PQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSW 1071
                + + +  R    +     ++G ++GLCGN+D    N+M  P      N   FG+SW
Sbjct: 2441 ---ELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSW 2497

Query: 1072 AAVECPDTL--DPRDMCVLNP-------LREPFAKKECS------------ILLSE---V 1107
              V+  D L   PR +            LR      ECS             +L++    
Sbjct: 2498 -EVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGP 2556

Query: 1108 FEICHPVVDVTWFYSNCLTDTC 1129
            F  CH  V    F  +C+ D C
Sbjct: 2557 FAACHQTVAPEPFQEHCVLDLC 2578



 Score = 49.7 bits (117), Expect = 4e-05
 Identities = 119/546 (21%), Positives = 192/546 (35%), Gaps = 107/546 (19%)

Query: 1954 APALSIVEGLAEALATTTEANTSTTCVP---IAEQDCVRHI---CLEGQLIRVNQSQHCP 2007
            +P+   ++G  E     +       C P   ++E  CV      C +     +   +   
Sbjct: 2225 SPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWV 2284

Query: 2008 QGAAPPRCGILGLAVRVGGDRCCPLWECAC---------------RCSIFPDLSFVTFDG 2052
                  +C   G A++ G  RC     C                 +CS++ D  ++TFDG
Sbjct: 2285 SSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDG 2344

Query: 2053 SHVALFKEAIYILSQSPDEMLT-VHVLDCKSANLGHLNWPPFCLVMLN---MTHLAHQVT 2108
                L     Y+L ++ D +   V  L  +  N      PP   + L     T   ++V 
Sbjct: 2345 FSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMD---PPRSSIFLQEVITTVYGYKVQ 2401

Query: 2109 IDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTS 2168
            +      V  + +   P       R+   G    ++T  ++ + +      +I   S  S
Sbjct: 2402 LQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVI---SLPS 2458

Query: 2169 KAQG--HGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQV-------------PSS 2213
              +G   GLCG  D +  ND+ L  G++    ++   F +SW+V             P+ 
Sbjct: 2459 MYEGLVSGLCGNYDKNRKNDMMLPSGALT---QNLNTFGNSWEVKTEDALLRFPRAIPAE 2515

Query: 2214 LTSVGQTRFRPDSCATTDCSPCLRMVSNRT------------FSACHRFVPPESFCELWI 2261
                G           ++CSP  ++ SN T            F+ACH+ V PE F E  +
Sbjct: 2516 EEGQGAELGLRTGLQVSECSP-EQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCV 2574

Query: 2262 RDTKYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQD 2321
             D    Q P     +   +     V   +  S+    L S           C+P +    
Sbjct: 2575 LDLCSAQDPREQEELRCQVLSGHGVSSRYHISELYDTLPS---------ILCQPGR--PR 2623

Query: 2322 GILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCI------PEAKCACTDSMGVPRALGE 2375
            G+ GPL                G +  R+H  LC+      P A C CT S G+   LG 
Sbjct: 2624 GLRGPL---------------RGRL--RQHPRLCLQWHPEPPLADCGCT-SNGIYYQLG- 2664

Query: 2376 TWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCN 2435
              +S L+  C  +C    + +   L C    P SC R GEV  L      C   + C+ N
Sbjct: 2665 --SSFLTEDCSQRCTCASSRI---LLC---EPFSC-RAGEVCTLGNHTQGCFPESPCLQN 2715

Query: 2436 QTLCEG 2441
                +G
Sbjct: 2716 PCQNDG 2721



 Score = 32.7 bits (73), Expect = 5.3
 Identities = 25/95 (26%), Positives = 33/95 (34%), Gaps = 19/95 (20%)

Query: 707  CEASKEYSPCVAPCGRTCQDLASPE-ACGVDGGDDLSRDECVEGCACPPDTYLDTQADLC 765
            C  +  Y  C  P   +C+   SP  +CG           C EGC C P          C
Sbjct: 1044 CPPNARYESCACPA--SCK---SPRPSCG---------PLCREGCVCNPGFLFSDNH--C 1087

Query: 766  VPRNQCSCHFQGVDYPPGDS--DIPSLGHCHCKDG 798
            +  + C+C +    Y PG          HC C  G
Sbjct: 1088 IQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPG 1122


>gi|27881494 zonadhesin isoform 6 [Homo sapiens]
          Length = 2721

 Score =  230 bits (586), Expect = 2e-59
 Identities = 201/752 (26%), Positives = 299/752 (39%), Gaps = 77/752 (10%)

Query: 79   CRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS----FSIQVHNDPQCGSSPYTCS 134
            C  +G  H  TFDG ++   GK +Y L    +P G S    F +   N+ Q G    +C 
Sbjct: 1156 CLVYGDPHYVTFDGRHFGFMGKCTYILA---QPCGNSTDPFFRVTAKNEEQ-GQEGVSCL 1211

Query: 135  RAVSLFFVGEQEIHLAK--EVTHGGMRVQLPHVMGSARLQQLAG-YVIVRHQSAFTLAWD 191
              V +  + E  + L K      GG +V LP +         +G +V ++ +    + WD
Sbjct: 1212 SKVYVT-LPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWD 1270

Query: 192  GASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPG 251
            G   +Y+ +S    G   GLCGN + +  +D +   G    D  E  +SWQ         
Sbjct: 1271 GDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQEC 1330

Query: 252  PTTSSLPRPPCLQQNPGTMQGVYEQCEALL--RPPFDACHAYVSPLPFTASCTSDLCQSM 309
                 +  P C      +M G    C  L+    PF+ C  +V    F  SC  D+C   
Sbjct: 1331 QKYQVVNSPSCDSSLQSSMSGP-GFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQ 1389

Query: 310  GDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRA 369
            G     C  ++     C  AG  ++ WR +   C + C   +  Y+ C   CP +CH   
Sbjct: 1390 GLQHLLCTHMSTMTTTCQDAGHAVKPWR-EPHFCPMACPPNS-KYSLCAKPCPDTCHSGF 1447

Query: 370  SCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSV-------VKEDC-N 421
            S +     CV+ C C  G +     C+  ++C C     L+P GS         K  C  
Sbjct: 1448 SGMFCSDRCVEACECNPGFVLSGLECIPRSQCGC-----LHPAGSYFKVGERWYKPGCKE 1502

Query: 422  TCTCTSGK------WECST--------------AVCPAECSVTGDIHFTTFDGRRYTFPA 461
             C C S        W C                A   A C+ +GD H+ TFDG  + F  
Sbjct: 1503 LCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMG 1562

Query: 462  TCQYILAK---SRSSGT-FTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDV 517
            TC Y+L +   SRS  + F V+  N   G   + + +++V V +       ++L +   V
Sbjct: 1563 TCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFD---LSISLLRGCKV 1619

Query: 518  LLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVG 577
            +L      +P +        RLSS  + + TN G++V YD   L + + V   +     G
Sbjct: 1620 MLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHL-VEVTVPSSYGGQLCG 1678

Query: 578  LCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSP---LVSGSPLDPCDVHLQAAS 634
            LCG +N N+ DD L P           G +WK   +  P   LV G P   C  +  A +
Sbjct: 1679 LCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKP-SSCQENSMADA 1737

Query: 635  YSVQACSVLTGEM--FAPCSAFLSPVPYFEQCRRDAC--RCGQPCLCATLAHYAHLCRRH 690
            ++ + C++L      F+ C   + P   F  C    C  +     LC +L  YA LC + 
Sbjct: 1738 WN-KNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQA 1796

Query: 691  GLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGC 750
            G    +R R   C + C     YSPC +PC  TC  + +P  C            C E C
Sbjct: 1797 GQAPAWRNR-TFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCP-------KALPCAESC 1848

Query: 751  ACPPDTYLDTQADLCVPRNQCSCHFQGVDYPP 782
             C     L   +  CVP  QC C      Y P
Sbjct: 1849 ECQKGHILSGTS--CVPLGQCGCTDPAGSYHP 1878



 Score =  224 bits (570), Expect = 1e-57
 Identities = 218/885 (24%), Positives = 348/885 (39%), Gaps = 127/885 (14%)

Query: 25   ERRLHRAKCAPSYLFS---CFNGGEC--VHPA-----------------FCDCRRFNATG 62
            +R +   +C P ++ S   C    +C  +HPA                  C C   N   
Sbjct: 1454 DRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRI- 1512

Query: 63   PRCQM--------------VYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGR 108
             RCQ               +Y    +  + C A G  H  TFDG  ++  G  +Y L   
Sbjct: 1513 -RCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRP 1571

Query: 109  HEPEGQS--FSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAK--EVTHGGMRVQLPH 164
                 Q   F +   N+ + G    +  +AV +  V +  I L +  +V   G RV LP 
Sbjct: 1572 CWSRSQDSYFVVSATNENRGGILEVSYIKAVHVT-VFDLSISLLRGCKVMLNGHRVALPV 1630

Query: 165  VMGSAR--LQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDD 222
             +   R  ++  +  V++       + +DG+  V + +     G   GLCGN N +  DD
Sbjct: 1631 WLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDD 1690

Query: 223  LVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQ-CEALL 281
             +    KL  D ++   +W+    ++P         +P   Q+N  +M   + + C  L+
Sbjct: 1691 NLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGG--KPSSCQEN--SMADAWNKNCAILI 1746

Query: 282  RP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQ 339
             P  PF  CH  V P    ASC    C + GD    CR+L  YA  CAQAG+    WR +
Sbjct: 1747 NPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQ-APAWRNR 1805

Query: 340  LRQCTVHCKEKAFTYNECIACCPASC----HPRASCVDSEIACVDGCYCPNGLIFEDGGC 395
               C + C   + +Y+ C + CP +C    +PR  C    + C + C C  G I     C
Sbjct: 1806 -TFCPMRCPPGS-SYSPCSSPCPDTCSSINNPR-DC-PKALPCAESCECQKGHILSGTSC 1861

Query: 396  VAPAECPC-EFHGTLYPPGS--VVKEDC-NTCTCT-SGKWECSTAVCPAE---------- 440
            V   +C C +  G+ +P G     +  C   CTC+      C  + C             
Sbjct: 1862 VPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLL 1921

Query: 441  ---------CSVTGDIHFTTFDGRRYTFPATCQYILAK----SRSSGTFTVTLQNAPCGL 487
                     C + G+ H+ +FDG  ++ P  C  +L K    + +   F ++ ++     
Sbjct: 1922 RCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEG 1981

Query: 488  NQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVR 547
              +   +  V + ++     QVTL +   VL+  +   +P  +       + SS++  V 
Sbjct: 1982 GTEAFRLHEVYIDIYD---AQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVN 2038

Query: 548  TNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNS 607
              +GV+V +D   L L +++   +     G+CG FN   +D+ + P     ++   F NS
Sbjct: 2039 IKIGVQVKFDGNHL-LEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNS 2097

Query: 608  WKTLS---ACSPLVSGSPLDPCD-----------VHLQAASYSVQACSVLTGEMFAPCSA 653
            WK      +C  L+      P +             L+ A    +A   L   ++A C++
Sbjct: 2098 WKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEA--ALRAPVWAQCAS 2155

Query: 654  FLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASK 711
             +   P+   C    C  G     LC  L  +   C+  GL          C L C A  
Sbjct: 2156 RIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYS 2215

Query: 712  EYSPCVAPCGRTCQDLASPEACGVDGGDDLSR--DECVEGCACPPDTYLDTQADLCVPRN 769
             Y+ C+  C  +C DL        DG  + ++    C EGC C P   L    D CVPR+
Sbjct: 2216 SYTNCLPSCSPSCWDL--------DGRCEGAKVPSACAEGCICQPGYVL--SEDKCVPRS 2265

Query: 770  QCSC-HFQGVDYPPGDSDIPS--LGHCHCKDGVMSC-DSRAPAAA 810
            QC C    G   P G S + S     C C  G + C D R P+ +
Sbjct: 2266 QCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQCGDFRCPSGS 2310



 Score =  179 bits (454), Expect = 3e-44
 Identities = 144/476 (30%), Positives = 196/476 (41%), Gaps = 63/476 (13%)

Query: 335  GWRTQLRQCTVHCKEKAFTYNECIACCPASCH-PRASCVDSEIACVDGCYCPNGLIFEDG 393
            G  T  R  T  C   A  Y  C   CPASC  PR SC      C +GC C  G +F D 
Sbjct: 1032 GTTTTSRSSTERCPPNA-RYESC--ACPASCKSPRPSCGP---LCREGCVCNPGFLFSDN 1085

Query: 394  GCVAPAECPCEFHGTLYPPGSV-----VKEDCN------------------TCTCTSGKW 430
             C+  + C C ++   Y PG+        E C                    C   +G++
Sbjct: 1086 HCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQY 1145

Query: 431  ECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGT---FTVTLQNAPCGL 487
             C      A C V GD H+ TFDGR + F   C YILA+   + T   F VT +N   G 
Sbjct: 1146 GCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQG- 1204

Query: 488  NQDG-ACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRV 546
             Q+G +C+  V V L   P   VTL +    L+  Q   +P        +   S  F+ +
Sbjct: 1205 -QEGVSCLSKVYVTL---PESTVTLLKGRRTLVGGQQVTLPAIPSKGVFL-GASGRFVEL 1259

Query: 547  RTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGN 606
            +T  G+RV +D +  +LY+ V   +     GLCG ++GN+ +D L   G P    +  GN
Sbjct: 1260 QTEFGLRVRWDGD-QQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGN 1318

Query: 607  SWKT----LSACSPL-VSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVP 659
            SW+T       C    V  SP   CD  LQ++      C  L  T   F  C   +    
Sbjct: 1319 SWQTDQDEDQECQKYQVVNSP--SCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAAS 1376

Query: 660  YFEQCRRDAC--RCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCV 717
            +F+ C  D C  +  Q  LC  ++     C+  G  V        C ++C  + +YS C 
Sbjct: 1377 FFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCA 1436

Query: 718  APCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSC 773
             PC  TC    S   C          D CVE C C P   L      C+PR+QC C
Sbjct: 1437 KPCPDTCHSGFSGMFCS---------DRCVEACECNPGFVLSGLE--CIPRSQCGC 1481



 Score =  168 bits (426), Expect = 6e-41
 Identities = 195/782 (24%), Positives = 295/782 (37%), Gaps = 156/782 (19%)

Query: 78   ICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS--FSIQV-HNDPQCGSSPYTCS 134
            +C+  G+ H  +FDG  + +    +  LV    P      F I   H   + G+  +   
Sbjct: 1930 VCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLH 1989

Query: 135  RAVSLFFVGEQEIHLAKEVTHGGMRVQLPHV--MGSARLQQLAGYVIVRHQSAFTLAWDG 192
                  +  +  +     V     +V LP +  +    ++  + Y IV  +    + +DG
Sbjct: 1990 EVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDG 2049

Query: 193  ASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGP 252
               + I++     G   G+CGN N + +D+L+  S ++ +   EFV+SW+++  +    P
Sbjct: 2050 NHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDID----P 2105

Query: 253  TTSSL-----PRPPCLQQNPG------TMQGVYEQCEALLRPPFDA-CHAYVSPLPFTAS 300
            +  SL       P   Q+NP        ++   E+CEA LR P  A C + +   PF   
Sbjct: 2106 SCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVD 2165

Query: 301  CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 360
            C + LC+  G     C+AL  +   C   G     WR     C + C   + +Y  C+  
Sbjct: 2166 CANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNS-SFCPLECPAYS-SYTNCLPS 2223

Query: 361  CPASCHPR-ASCVDSEI--ACVDGCYCPNGLIFEDGGCVAPAECPC-EFHGTLYPPG-SV 415
            C  SC      C  +++  AC +GC C  G +  +  CV  ++C C + HG   P G S 
Sbjct: 2224 CSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSW 2283

Query: 416  VKEDCNT-CTCTSGKWECSTAVCPA---------------------ECSVTGDIHFTTFD 453
            V   C   C CT G  +C    CP+                     +CSV GD  + TFD
Sbjct: 2284 VSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFD 2343

Query: 454  GRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTL-- 511
            G  Y       Y+L K         T+   P G+  +   V+  + +    PR  + L  
Sbjct: 2344 GFSYRLQGRMTYVLIK---------TVDVLPEGV--EPLLVEGRNKM--DPPRSSIFLQE 2390

Query: 512  -----------TQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREG 560
                        QAG  L+ +  K+  PY                 R N  +RV     G
Sbjct: 2391 VITTVYGYKVQLQAGLELVVNNQKMAVPY-----------------RPNEHLRVTL--WG 2431

Query: 561  LRLYLQVDQRWVED------------------TVGLCGTFNGNTQDDFLSPVGVPESTPQ 602
             RLYL  D   V                      GLCG ++ N ++D + P G       
Sbjct: 2432 QRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLN 2491

Query: 603  LFGNSWKTLS-------------------ACSPLVSGSPLDPCDVHLQAASYSVQACSVL 643
             FGNSW+  +                   A   L +G  +  C    Q AS S QAC VL
Sbjct: 2492 TFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPE-QLASNSTQACRVL 2550

Query: 644  TGEM--FAPCSAFLSPVPYFEQCRRDACRCGQP-----CLCATLAHYAHLCRRHGLPV-D 695
                  FA C   ++P P+ E C  D C    P       C  L+ YA LC+  G  +  
Sbjct: 2551 ADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAG 2610

Query: 696  FRARLPACALSCEASKEYSPCVA-PCGR--TCQDLASPEACGVDGGDDLSRDECVEGCAC 752
            +R R       CE     SPC+  PC     C++  +   C  + G       C+E    
Sbjct: 2611 WRDR-----TLCE-----SPCLQNPCQNDGQCREQGATFTCECEVG--YGGGLCMEPRDA 2658

Query: 753  PP 754
            PP
Sbjct: 2659 PP 2660



 Score =  150 bits (379), Expect = 2e-35
 Identities = 226/1035 (21%), Positives = 364/1035 (35%), Gaps = 165/1035 (15%)

Query: 1429 PRTPTHRPALTPAAPLTTALNP-PVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTES 1487
            P  P   P  +     TT L   P  +T++P VS      T ++P      + P  PTE 
Sbjct: 540  PELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPT--VPKEKPTIPTEK 597

Query: 1488 PASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSP 1547
            P       ++ +      S    +  + PT       + + + T+    S   T+S+  P
Sbjct: 598  PTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTI---PSEKPTISTEKP 654

Query: 1548 PAPRFPLMTKAVTVRGHGSLPVRTTPLQPSLTASPSSRPVASPGAISRSPTSSGSHKAVL 1607
              P     T           PV  T  +PS+     S P   P  IS   T   + K  +
Sbjct: 655  TVPTEEPTTPTEETTTSMEEPVIPTE-KPSIPTEKPSIPTEKP-TISMEETIISTEKPTI 712

Query: 1608 TPAVTKV-ISRTGVPQPTQAQSASSPSTPL------TVAGTAAEQVPVSPLATRSL---E 1657
            +P    +   +  +P      S   P+TP       T   T + + P +P    ++   +
Sbjct: 713  SPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEK 772

Query: 1658 IVLSTEKGEAGHSQPMGSPASPQPHPLPSA--PPRPAQHTTMATRSPALPPETPAAASLS 1715
            + + TEK       P   P  P   P  S   P  P + TT++T  P++P E P   +  
Sbjct: 773  LTIPTEKPTI----PTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEE 828

Query: 1716 TATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQ 1775
            T T         S+E T  S          ++P+ K      ++T  P        + P+
Sbjct: 829  TTT---------SVEETTIST------EKLTIPMEK----PTISTEKPTIPTEKPTISPE 869

Query: 1776 ATTLPAQTLS-----PVLPF--TPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLP 1828
              T+P + L+     P +P   T  +  +   PT   P  +   P   +    PT   +P
Sbjct: 870  KLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTE-KPTISPEKP--TISTEKPT---IP 923

Query: 1829 VAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGSAEGGPTELTPATSHPLTPLVAEP 1888
              + T      +P + TT    I ++++++PT         P +LT  T  P    ++  
Sbjct: 924  TEKPT------IPTEETT----ISTEKLTIPTE---KPTISPEKLTIPTEKPT---ISTE 967

Query: 1889 EGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLAEAHGTSAGPHLAAEPVDEATTE 1948
            +       L +PT          T P + +  L P     H +     LAA         
Sbjct: 968  KPTIPTEKLTIPTEKPTIPTEKPTIPTEKLTALRPP----HPSPTATGLAA-----LVMS 1018

Query: 1949 PSGRSAPALSIVEGLAEALATTTEA-----------------NTSTTCVPIAEQDCV--- 1988
            P   S P  S++ G      ++TE                  +   +C P+  + CV   
Sbjct: 1019 PHAPSTPMTSVILGTTTTSRSSTERCPPNARYESCACPASCKSPRPSCGPLCREGCVCNP 1078

Query: 1989 -----RHICLEG----------------QLIRVNQSQHC---PQGAAP---PRCGILGLA 2021
                  + C++                 +    N ++HC   P         +CG   + 
Sbjct: 1079 GFLFSDNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVC 1138

Query: 2022 VRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQ----SPDEMLTVHV 2077
                G   C  +     C ++ D  +VTFDG H     +  YIL+Q    S D    V  
Sbjct: 1139 QLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTA 1198

Query: 2078 LDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDT 2137
             + +    G       CL  + +T     VT+ +  R +    Q   P +   G  +  +
Sbjct: 1199 KNEEQGQEG-----VSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGAS 1253

Query: 2138 GHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGG 2197
            G    + T   ++++W      + V  S T   +  GLCG  DG++ ND    DGS  G 
Sbjct: 1254 GRFVELQTEFGLRVRW-DGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGD 1312

Query: 2198 AEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSP---------CLRMV-SNRTFSAC 2247
             E+     +SWQ         Q +++  +  + D S          C R+V ++  F  C
Sbjct: 1313 KEELG---NSWQTDQDEDQECQ-KYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETC 1368

Query: 2248 HRFVPPESFCELWIRDTKYVQ----QPCVALTVYVAMCHKF-HVCIEWRRSDYCPFLCSS 2302
               V   SF +  + D    Q      C  ++     C    H    WR   +CP  C  
Sbjct: 1369 LLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPP 1428

Query: 2303 DSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCA 2362
            +S Y  C   C  P TC  G  G    + C    E C C+ G +L       CIP ++C 
Sbjct: 1429 NSKYSLCAKPC--PDTCHSGFSGMFCSDRCV---EACECNPGFVL---SGLECIPRSQCG 1480

Query: 2363 CTDSMGVPRALGETW 2377
            C    G    +GE W
Sbjct: 1481 CLHPAGSYFKVGERW 1495



 Score =  108 bits (269), Expect = 1e-22
 Identities = 102/406 (25%), Positives = 158/406 (38%), Gaps = 63/406 (15%)

Query: 810  ACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFL 869
            ACP    +  C+    D       TC      +  S R  C+  C C  G +  G  C  
Sbjct: 1425 ACPPNSKYSLCAKPCPD-------TCHSGFSGMFCSDR--CVEACECNPGFVLSGLECIP 1475

Query: 870  PEECPCTWKGKEYFP-GDQVMSP-C-HTCVCQRGS-FQCTLHPC---------------- 909
              +C C      YF  G++   P C   CVC+  +  +C    C                
Sbjct: 1476 RSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCH 1535

Query: 910  ---ASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKS----TSDVSFSVIVENVN------ 956
               A+TCTA GD HY TFDG    F+G C   L +     + D  F V   N N      
Sbjct: 1536 AQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILE 1595

Query: 957  -CYSSGMICRKF-ISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQE 1014
              Y   +    F +SI++     V  +      P      +  +   R+    ++ +   
Sbjct: 1596 VSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTI---RLSSNLVLLYTNF 1652

Query: 1015 HITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAV 1074
             + + +D    V V     + GQL GLCGN++  ++++   P+     +  + G++W   
Sbjct: 1653 GLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAW--- 1709

Query: 1075 ECPDTLDPR--------DMCVLNPLREPFAKKECSILLSEV--FEICHPVVDVTWFYSNC 1124
            + P++ +P           C  N + + +  K C+IL++    F  CH VV     +++C
Sbjct: 1710 KLPESSEPGCFLVGGKPSSCQENSMADAW-NKNCAILINPQGPFSQCHQVVPPQSSFASC 1768

Query: 1125 LTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDC 1170
            +   CG    GD    C S+ AYA  C Q G A  WR    CP  C
Sbjct: 1769 VHGQCGTK--GDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRC 1812



 Score =  107 bits (268), Expect = 1e-22
 Identities = 100/406 (24%), Positives = 147/406 (36%), Gaps = 55/406 (13%)

Query: 804  SRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRH 863
            SR+    CP    + +C+             C     +   S    C  GC C  G L  
Sbjct: 1037 SRSSTERCPPNARYESCA-------------CPASCKSPRPSCGPLCREGCVCNPGFLFS 1083

Query: 864  GDACFLPEECPCTWKGKEYFPGDQVMSP--------------------CHT-CVCQRGSF 902
             + C     C C +    Y PG +  SP                    C T  VCQ  + 
Sbjct: 1084 DNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNG 1143

Query: 903  QCTLHPCA--STCTAYGDRHYRTFDGLPFDFVGACKVHLVK---STSDVSFSVIVENVNC 957
            Q   HP A  +TC  YGD HY TFDG  F F+G C   L +   +++D  F V  +N   
Sbjct: 1144 QYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQ 1203

Query: 958  YSSGMICRKFISINVGNSLIVFDDDS----GNPSPESFLDDKQEVHTWRVGFFTLVHFPQ 1013
               G+ C   + + +  S +          G           + V     G F  +   +
Sbjct: 1204 GQEGVSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQ-TE 1262

Query: 1014 EHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAA 1073
              + + WD    ++V     + G+L GLCGN+D  + N+    +     + +E G+SW  
Sbjct: 1263 FGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQT 1322

Query: 1074 VECPDTLDPRDMCVLNPLREPFAKKE------CSILLSE--VFEICHPVVDVTWFYSNCL 1125
             +  D    +   V +P  +   +        C  L+     FE C   V    F+ +C+
Sbjct: 1323 DQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCM 1382

Query: 1126 TDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1170
             D CG    G     C  +S     C   G AV  WR P  CP  C
Sbjct: 1383 LDMCGFQ--GLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMAC 1426



 Score = 93.2 bits (230), Expect = 3e-18
 Identities = 93/378 (24%), Positives = 147/378 (38%), Gaps = 69/378 (18%)

Query: 2036 ACRCSIFPDLSFVTFDGSHVALFKEAIYIL-----SQSPDEMLTVHVLDCKSANLGHLNW 2090
            A  C+   D  ++TFDG+         Y+L     S+S D    V   +     +  +++
Sbjct: 1539 AATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSY 1598

Query: 2091 PPF---------------CLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIE 2135
                              C VMLN     H+V +            PVW    R   R+ 
Sbjct: 1599 IKAVHVTVFDLSISLLRGCKVMLN----GHRVAL------------PVWLAQGRVTIRL- 1641

Query: 2136 DTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLKDGS 2193
             + ++ ++ T   +Q+++    G  +VE +  S   G   GLCG  + ++ +D    D  
Sbjct: 1642 -SSNLVLLYTNFGLQVRY---DGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRK 1697

Query: 2194 VVGGAEDPAPFLDSWQVP-SSLTSVGQTRFRPDSCATTDCSP-----CLRMVSNR-TFSA 2246
            + G   D      +W++P SS         +P SC     +      C  +++ +  FS 
Sbjct: 1698 LAG---DSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQ 1754

Query: 2247 CHRFVPPESFCELWIR-------DTKYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFL 2299
            CH+ VPP+S     +        DT  +   C +L  Y ++C +      WR   +CP  
Sbjct: 1755 CHQVVPPQSSFASCVHGQCGTKGDTTAL---CRSLQAYASLCAQAGQAPAWRNRTFCPMR 1811

Query: 2300 CSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEA 2359
            C   S+Y  C + C  P TC   I  P D        E C C +G IL       C+P  
Sbjct: 1812 CPPGSSYSPCSSPC--PDTC-SSINNPRDCPKALPCAESCECQKGHIL---SGTSCVPLG 1865

Query: 2360 KCACTDSMGVPRALGETW 2377
            +C CTD  G    +GE W
Sbjct: 1866 QCGCTDPAGSYHPVGERW 1883



 Score = 86.3 bits (212), Expect = 4e-16
 Identities = 86/377 (22%), Positives = 141/377 (37%), Gaps = 60/377 (15%)

Query: 61   TGPRCQMVY-----NAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHE--PEG 113
            +G  CQ+       N   ++   C  +G     TFDG  Y L G+ +Y L+   +  PEG
Sbjct: 2308 SGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEG 2367

Query: 114  -QSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQ 172
             +   ++  N      S       ++  +  + ++    E+     ++ +P+        
Sbjct: 2368 VEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRV 2427

Query: 173  QLAG---YVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGK 229
             L G   Y++   +    +++ G     I +     G   GLCGN + + K+D++  SG 
Sbjct: 2428 TLWGQRLYLVTDFE--LVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGA 2485

Query: 230  LTDDVVEFVHSWQEQAPNQPPGPTTSSLPRP-PCLQQNPGTMQGV--------------- 273
            LT ++  F +SW+ +  +          PR  P  ++  G   G+               
Sbjct: 2486 LTQNLNTFGNSWEVKTED-----ALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLA 2540

Query: 274  ---YEQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMG---DVATWCRALAEYARA 325
                + C  L  P  PF ACH  V+P PF   C  DLC +          C+ L+ YA  
Sbjct: 2541 SNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAIL 2600

Query: 326  CAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCP 385
            C +AG  L GWR +       C+           C    C     C   E      C C 
Sbjct: 2601 CQEAGAALAGWRDR-----TLCES---------PCLQNPCQNDGQC--REQGATFTCECE 2644

Query: 386  NGLIFEDGGCVAPAECP 402
             G  +  G C+ P + P
Sbjct: 2645 VG--YGGGLCMEPRDAP 2659



 Score = 84.3 bits (207), Expect = 2e-15
 Identities = 103/425 (24%), Positives = 146/425 (34%), Gaps = 79/425 (18%)

Query: 811  CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLP 870
            CPA   + NC    +      +  CE             C  GC C  G +   D C   
Sbjct: 2211 CPAYSSYTNCLPSCSPSCWDLDGRCE------GAKVPSACAEGCICQPGYVLSEDKCVPR 2264

Query: 871  EECPC--TWKGKEYFPGDQVMSPC-HTCVCQRGSFQCTLHPCAS---------------- 911
             +C C     G        V S C   CVC  G+ QC    C S                
Sbjct: 2265 SQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCV 2324

Query: 912  -----TCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSV---IVENVNCYS---S 960
                  C+ YGD  Y TFDG  +   G     L+K+   +   V   +VE  N      S
Sbjct: 2325 SDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRS 2384

Query: 961  GMICRKFIS--------INVGNSLIVFDDDSGNP-SPESFLDDKQEVHTWRVGFFTLVHF 1011
             +  ++ I+        +  G  L+V +     P  P   L     V  W    + +  F
Sbjct: 2385 SIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHL----RVTLWGQRLYLVTDF 2440

Query: 1012 PQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSW 1071
                + + +  R    +     ++G ++GLCGN+D    N+M  P      N   FG+SW
Sbjct: 2441 ---ELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSW 2497

Query: 1072 AAVECPDTL--DPRDMCVLNP-------LREPFAKKECS------------ILLSE---V 1107
              V+  D L   PR +            LR      ECS             +L++    
Sbjct: 2498 -EVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGP 2556

Query: 1108 FEICHPVVDVTWFYSNCLTDTCGCSQGGDC-ECFCASVSAYAHQCCQHGVAV-DWRTPRL 1165
            F  CH  V    F  +C+ D C      +  E  C  +S YA  C + G A+  WR   L
Sbjct: 2557 FAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTL 2616

Query: 1166 CPYDC 1170
            C   C
Sbjct: 2617 CESPC 2621



 Score = 81.3 bits (199), Expect = 1e-14
 Identities = 105/477 (22%), Positives = 174/477 (36%), Gaps = 44/477 (9%)

Query: 1393 EPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPV 1452
            +P V +   ++  E     +  PT   E+P +S E P  P+ +P + P+   T     P 
Sbjct: 569  KPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNM-PSEKPTIPSEKPT 627

Query: 1453 TATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPA--SKGVTASLLAIPHTPESSSLP 1510
              TE+P +     + T+       +++ P  PTE P   ++  T S+       E  S+P
Sbjct: 628  ILTEKPTIP--SEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIP 685

Query: 1511 -----VALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLM-TKAVTVRGH 1564
                 +  + PT  M    + T + T I    P I     + P  +  +   K  T    
Sbjct: 686  TEKPSIPTEKPTISMEETIISTEKPT-ISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEK 744

Query: 1565 GSLPVRTTPLQPSLTASPSSRPVASPGAI---SRSPTSSGSHKAVLTPAVTKVISRTGVP 1621
             ++P     + P    +P+ +P  SP  +   +  PT       + T   T        P
Sbjct: 745  PTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTP 804

Query: 1622 QPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQ- 1680
                  S   PS P+         +P     T   E  +STEK      +P  S   P  
Sbjct: 805  TEETTISTEKPSIPM-----EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTI 859

Query: 1681 PHPLPSAPPR----PAQHTTMATRSPALPPE--TPAAASLSTATDGLAATPFMSLESTRP 1734
            P   P+  P     P +  T+ T  P +P E  T +   L+  T+    +P     ST  
Sbjct: 860  PTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEK 919

Query: 1735 SQLLSGLP----PDTSLPLAK--VGTSAPVATP--------GPKASVITTPLQPQATTLP 1780
              + +  P     +T++   K  + T  P  +P         P  S     +  +  T+P
Sbjct: 920  PTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIP 979

Query: 1781 AQ--TLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTAS 1835
             +  T+    P  P     A  P H +P A G A  L++    P++ +  V  GT +
Sbjct: 980  TEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLA-ALVMSPHAPSTPMTSVILGTTT 1035



 Score = 76.6 bits (187), Expect = 3e-13
 Identities = 87/428 (20%), Positives = 153/428 (35%), Gaps = 88/428 (20%)

Query: 811  CPAGQVFVNCSDLHTDL--ELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACF 868
            CP G  +  CS    D    ++  R C + L         PC   C C +G +  G +C 
Sbjct: 1812 CPPGSSYSPCSSPCPDTCSSINNPRDCPKAL---------PCAESCECQKGHILSGTSCV 1862

Query: 869  LPEECPCTWKGKEYFPGDQVMSPCHTCV----CQRGS----FQCTLHP------------ 908
               +C CT     Y P  +     +TC     C   +    FQ T  P            
Sbjct: 1863 PLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLR 1922

Query: 909  CAST----CTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDV------------------ 946
            C ++    C   G+ HY +FDG       AC + LVK                       
Sbjct: 1923 CRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGG 1982

Query: 947  --SFSVIVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVG 1004
              +F +    ++ Y + +  +K   + + +  +     S  P           +   ++G
Sbjct: 1983 TEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIG 2042

Query: 1005 FFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNP 1064
                       + + +D    + ++    + G++ G+CGNF+ +  +E+  P +    + 
Sbjct: 2043 -----------VQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSD 2091

Query: 1065 QEFGSSWAAVE----CPDTL------------DPRDMCVLNPLREPFAKKEC-SILLSEV 1107
             EF +SW   +    C   L            +P   C    LR   A+++C + L + V
Sbjct: 2092 SEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRR--AREKCEAALRAPV 2149

Query: 1108 FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVD-WRTPRLC 1166
            +  C   +D+T F  +C      C  GG  +  C ++ A+   C   G+    WR    C
Sbjct: 2150 WAQCASRIDLTPFLVDCANTL--CEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFC 2207

Query: 1167 PYDCDFFN 1174
            P +C  ++
Sbjct: 2208 PLECPAYS 2215



 Score = 76.3 bits (186), Expect = 4e-13
 Identities = 77/322 (23%), Positives = 129/322 (40%), Gaps = 35/322 (10%)

Query: 2106 QVTIDRFNRKVTVDLQPVWPPVSRY-GFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEA 2164
            QVT+ + +R +    Q   P +S+  G  ++ +    ++     +Q+++   + L+ +E 
Sbjct: 1999 QVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKF-DGNHLLEIEI 2057

Query: 2165 SKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQV----PSSLTSVGQT 2220
              T   +  G+CG  + +  ++L +    V   A   + F++SW+     PS  + +   
Sbjct: 2058 PTTYYGKVCGMCGNFNDEEEDELMMPSDEV---ANSDSEFVNSWKDKDIDPSCQSLLVDE 2114

Query: 2221 RFRPDSCATTDCSPCLRMVSNRTFSACHRFV--PPESFCELWIRDTKYV----------- 2267
            +  P          C      R    C   +  P  + C   I  T ++           
Sbjct: 2115 QQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFG 2174

Query: 2268 ---QQPCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDG- 2322
               Q  C AL  + A C    +    WR S +CP  C + S+Y  C+ +C P     DG 
Sbjct: 2175 GLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGR 2234

Query: 2323 ILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLS 2382
              G   P  C    EGC+C  G +L       C+P ++C C D+ G    LG++W S  S
Sbjct: 2235 CEGAKVPSAC---AEGCICQPGYVLSEDK---CVPRSQCGCKDAHGGSIPLGKSWVS--S 2286

Query: 2383 GCCQHQCQAPDTIVPVDLGCPS 2404
            GC +        I   D  CPS
Sbjct: 2287 GCTEKCVCTGGAIQCGDFRCPS 2308



 Score = 75.9 bits (185), Expect = 5e-13
 Identities = 109/470 (23%), Positives = 168/470 (35%), Gaps = 91/470 (19%)

Query: 1363 PRVEGCVPVCPTPQVLDEVTQRCVYLEDCVEPAVW--VPTEALGNETLPPSQGL------ 1414
            P +    P  PT +      +    +E+ V P     +PTE     T  P+  +      
Sbjct: 647  PTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIIS 706

Query: 1415 ---PTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTTLQQ 1471
               PT S E+P +  E P  PT +  ++P  P TT    P   TE+P +SP         
Sbjct: 707  TEKPTISPEKPTIPTEKPTIPTEKSTISPEKP-TTPTEKPTIPTEKPTISP--------- 756

Query: 1472 PLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQT-PTPGMVSGAMETTRV 1530
                   + P  PTE P    ++   L IP   E  ++P    T PT        E T  
Sbjct: 757  -------EKPTTPTEKPT---ISPEKLTIP--TEKPTIPTEKPTIPTEKPTISTEEPTTP 804

Query: 1531 TVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRTTPLQPSLTASPSSRPVASP 1590
            T         T+S+  P  P    M K        +  V  T +       P  +P    
Sbjct: 805  T------EETTISTEKPSIP----MEKPTLPTEETTTSVEETTISTEKLTIPMEKP---- 850

Query: 1591 GAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTAAEQVPVSP 1650
              IS    +  + K  ++P                 +  + P+  LT+  T    +P+  
Sbjct: 851  -TISTEKPTIPTEKPTISP-----------------EKLTIPTEKLTIP-TEKPTIPIEE 891

Query: 1651 LATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPR-PAQHTTMATRSPALPPETP 1709
                + ++ + TEK      +P  S   P    +P+  P  P + TT++T    +P E P
Sbjct: 892  TTISTEKLTIPTEKPTISPEKPTISTEKP---TIPTEKPTIPTEETTISTEKLTIPTEKP 948

Query: 1710 AAA--SLSTATDGLAATPFMSLES-TRPSQLLSGLPPDTSLPLAKVGTSAPVATPGPKAS 1766
              +   L+  T+     P +S E  T P++ L+      ++P  K         P  K +
Sbjct: 949  TISPEKLTIPTE----KPTISTEKPTIPTEKLTIPTEKPTIPTEK------PTIPTEKLT 998

Query: 1767 VITTP-LQPQATTLPAQTLSPVLPFTP------AAMTQAHPPTHIAPPAA 1809
             +  P   P AT L A  +SP  P TP         T +   T   PP A
Sbjct: 999  ALRPPHPSPTATGLAALVMSPHAPSTPMTSVILGTTTTSRSSTERCPPNA 1048



 Score = 49.3 bits (116), Expect = 5e-05
 Identities = 85/407 (20%), Positives = 143/407 (35%), Gaps = 70/407 (17%)

Query: 1954 APALSIVEGLAEALATTTEANTSTTCVP---IAEQDCVRHI---CLEGQLIRVNQSQHCP 2007
            +P+   ++G  E     +       C P   ++E  CV      C +     +   +   
Sbjct: 2225 SPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWV 2284

Query: 2008 QGAAPPRCGILGLAVRVGGDRCCPLWECAC---------------RCSIFPDLSFVTFDG 2052
                  +C   G A++ G  RC     C                 +CS++ D  ++TFDG
Sbjct: 2285 SSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDG 2344

Query: 2053 SHVALFKEAIYILSQSPDEMLT-VHVLDCKSANLGHLNWPPFCLVMLN---MTHLAHQVT 2108
                L     Y+L ++ D +   V  L  +  N      PP   + L     T   ++V 
Sbjct: 2345 FSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMD---PPRSSIFLQEVITTVYGYKVQ 2401

Query: 2109 IDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTS 2168
            +      V  + +   P       R+   G    ++T  ++ + +      +I   S  S
Sbjct: 2402 LQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVI---SLPS 2458

Query: 2169 KAQG--HGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQV-------------PSS 2213
              +G   GLCG  D +  ND+ L  G++    ++   F +SW+V             P+ 
Sbjct: 2459 MYEGLVSGLCGNYDKNRKNDMMLPSGALT---QNLNTFGNSWEVKTEDALLRFPRAIPAE 2515

Query: 2214 LTSVGQTRFRPDSCATTDCSPCLRMVSNRT------------FSACHRFVPPESFCELWI 2261
                G           ++CSP  ++ SN T            F+ACH+ V PE F E  +
Sbjct: 2516 EEGQGAELGLRTGLQVSECSP-EQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCV 2574

Query: 2262 RDTKYVQQP-------CVALTVYVAMCHKFHVCIE-WRRSDYCPFLC 2300
             D    Q P       C  L+ Y  +C +    +  WR    C   C
Sbjct: 2575 LDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCESPC 2621



 Score = 32.7 bits (73), Expect = 5.3
 Identities = 25/95 (26%), Positives = 33/95 (34%), Gaps = 19/95 (20%)

Query: 707  CEASKEYSPCVAPCGRTCQDLASPE-ACGVDGGDDLSRDECVEGCACPPDTYLDTQADLC 765
            C  +  Y  C  P   +C+   SP  +CG           C EGC C P          C
Sbjct: 1044 CPPNARYESCACPA--SCK---SPRPSCG---------PLCREGCVCNPGFLFSDNH--C 1087

Query: 766  VPRNQCSCHFQGVDYPPGDS--DIPSLGHCHCKDG 798
            +  + C+C +    Y PG          HC C  G
Sbjct: 1088 IQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPG 1122


>gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens]
          Length = 1503

 Score =  160 bits (405), Expect = 2e-38
 Identities = 167/602 (27%), Positives = 229/602 (38%), Gaps = 118/602 (19%)

Query: 654  FLSPVPYFEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRA----RLPACALSCEA 709
            F  P    E CR   C+ GQ   C  L      C+   L V  R     R   C    E 
Sbjct: 850  FEGPAGSCEWCR---CQAGQVS-CVRLQCPPLPCK---LQVTERGSCCPRCRGCLAHGEE 902

Query: 710  SKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRN 769
              E S  V P      D A       +G    +R +C+  CA P     D     C P  
Sbjct: 903  HPEGSRWVPP------DSACSSCVCHEGVVTCARIQCISSCAQPRQGPHD-----CCP-- 949

Query: 770  QCS-CHFQGVDYPPGDSDIPSLGHCH---CK---DGVMS--CDSR--------------- 805
            QCS C  +G  Y PG+S  P    C    C+   +G  S  C  R               
Sbjct: 950  QCSDCEHEGRKYEPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQLLP 1009

Query: 806  -APAAACPA-GQVFVNCSDLHTDLELSRERTCE----QQLLNLSVSARGPCLS------- 852
              P   CP   +   NCS+     EL+    C     Q L  L +    P LS       
Sbjct: 1010 PGPQHCCPTCAEALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIHQACPELSCPLSERH 1069

Query: 853  ---GCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQ-VMSPCHTCVCQRGSFQCTLHP 908
               G  CP         C  P +  C  +G+E   G++  +  C +C C  G+ +C    
Sbjct: 1070 TPPGSCCP--------VCRAPTQS-CVHQGREVASGERWTVDTCTSCSCMAGTVRCQSQR 1120

Query: 909  CA-------------------------STCTAYGDRHYRTFDGLPFDFVGACKVHLVKST 943
            C+                         ++C A+GD HYRTFDG    F G+C   L K  
Sbjct: 1121 CSPLSCGPDKAPALSPGSCCPRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKDC 1180

Query: 944  SDVSFSVIVENVNCYSSGMICRKFISINVGNSLIVFDDDS-----GNPSPESFLDDKQEV 998
                FSV V N +   SG+   + +++ +G+  +    D      G+P    FL +    
Sbjct: 1181 HSGDFSVHVTNDDRGRSGVAWTQEVAVLLGDMAVRLLQDGAVTVDGHPVALPFLQEPLLY 1240

Query: 999  HTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPEN 1058
               R G   ++H  Q  + +LWD ++ V V     +QG+  GLCGNF+    ++++ PE 
Sbjct: 1241 VELR-GHTVILH-AQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEG 1298

Query: 1059 LELTNPQEFGSSWAAVE---------CPDTLDPRDMCVLNPLREPFAKKECSILLSEVFE 1109
            L L +   FG+SW   E             +DP         RE  A   C +L S  F 
Sbjct: 1299 LLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPCRAAGYRARRE--ANARCGVLKSSPFS 1356

Query: 1110 ICHPVVDVTWFYSNCLTDTCGCSQGGDCE-CFCASVSAYAHQCCQHGVAVDWRTPRLCPY 1168
             CH VV    F++ C+ D C C  G   + C C ++ AYA  C Q GV   WR P LC  
Sbjct: 1357 RCHAVVPPEPFFAACVYDLCACGPGSSADACLCDALEAYASHCRQAGVTPTWRGPTLCVV 1416

Query: 1169 DC 1170
             C
Sbjct: 1417 GC 1418



 Score =  159 bits (403), Expect = 3e-38
 Identities = 141/474 (29%), Positives = 188/474 (39%), Gaps = 74/474 (15%)

Query: 360  CCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKED 419
            C   +C P  SC  SE     G  CP         C AP +  C   G     G     D
Sbjct: 1053 CIHQAC-PELSCPLSERHTPPGSCCPV--------CRAPTQS-CVHQGREVASGERWTVD 1102

Query: 420  -CNTCTCTSGKWECSTAVC-------------------------PAECSVTGDIHFTTFD 453
             C +C+C +G   C +  C                         PA C   GD H+ TFD
Sbjct: 1103 TCTSCSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPASCMAFGDPHYRTFD 1162

Query: 454  GRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQ 513
            GR   F  +C Y+LAK   SG F+V + N   G     A  Q V+V+L       V L Q
Sbjct: 1163 GRLLHFQGSCSYVLAKDCHSGDFSVHVTNDDRG-RSGVAWTQEVAVLLGD---MAVRLLQ 1218

Query: 514  AGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVE 573
             G V + D + +  P+  +      L    + +    G++VL+D +  ++ + V   +  
Sbjct: 1219 DGAVTV-DGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWDGQS-QVEVSVPGSYQG 1276

Query: 574  DTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKT---LSACSPLVSGSPLDPCDVHL 630
             T GLCG FNG  QDD   P G+   +   FGNSW+    L    P  +G  +DPC    
Sbjct: 1277 RTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPC---- 1332

Query: 631  QAASYSVQ-----ACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCG-----QPCLCATL 680
            +AA Y  +      C VL    F+ C A + P P+F  C  D C CG       CLC  L
Sbjct: 1333 RAAGYRARREANARCGVLKSSPFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDAL 1392

Query: 681  AHYAHLCRRHGLPVDFRARLPACALSC--EASKEYSPCVAPCGRTCQDLASPEACGVDGG 738
              YA  CR+ G+   +R     C + C  E    +  C  PC RTC +   P        
Sbjct: 1393 EAYASHCRQAGVTPTWRGP-TLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLG------ 1445

Query: 739  DDLSRD---ECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPS 789
             +L+      CV GC CP    L      C+P   C       D P G    PS
Sbjct: 1446 -ELAAHCVRPCVPGCQCPAG--LVEHEAHCIPPEACPQVLLTGDQPLGARPSPS 1496



 Score =  158 bits (400), Expect = 6e-38
 Identities = 114/344 (33%), Positives = 152/344 (44%), Gaps = 26/344 (7%)

Query: 75   RDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCS 134
            R + C A+G  H  TFDG   +  G  SY L    +     FS+ V ND + G S    +
Sbjct: 1146 RPASCMAFGDPHYRTFDGRLLHFQGSCSYVLA--KDCHSGDFSVHVTNDDR-GRSGVAWT 1202

Query: 135  RAVSLFFVGEQEIHLAKE--VTHGGMRVQLPHVMGSARLQQLAGYVIVRH-QSAFTLAWD 191
            + V++  +G+  + L ++  VT  G  V LP +       +L G+ ++ H Q    + WD
Sbjct: 1203 QEVAVL-LGDMAVRLLQDGAVTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWD 1261

Query: 192  GASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPG 251
            G S V + +     G T GLCGN N   +DDL    G L      F +SWQ      P  
Sbjct: 1262 GQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGR 1321

Query: 252  PTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQ---- 307
            P ++     PC        +    +C  L   PF  CHA V P PF A+C  DLC     
Sbjct: 1322 PCSAGREVDPCRAAGYRARREANARCGVLKSSPFSRCHAVVPPEPFFAACVYDLCACGPG 1381

Query: 308  SMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCK-EKAFTYNECIACCPASCH 366
            S  D A  C AL  YA  C QAG     WR     C V C  E+ F ++EC   CP +C 
Sbjct: 1382 SSAD-ACLCDALEAYASHCRQAG-VTPTWRGP-TLCVVGCPLERGFVFDECGPPCPRTCF 1438

Query: 367  PR--------ASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECP 402
             +        A CV     CV GC CP GL+  +  C+ P  CP
Sbjct: 1439 NQHIPLGELAAHCVR---PCVPGCQCPAGLVEHEAHCIPPEACP 1479



 Score = 84.3 bits (207), Expect = 2e-15
 Identities = 113/404 (27%), Positives = 156/404 (38%), Gaps = 58/404 (14%)

Query: 1987 CVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACR---CSIFP 2043
            C    C+ G  +R  QSQ C    +P  CG    A  +    CCP   C  R   C  F 
Sbjct: 1104 CTSCSCMAGT-VRC-QSQRC----SPLSCGP-DKAPALSPGSCCP--RCLPRPASCMAFG 1154

Query: 2044 DLSFVTFDGSHVALFKEAIYILSQSPDEM-LTVHVLDCKSANLGHLNWPPFCLVMLNMTH 2102
            D  + TFDG  +       Y+L++       +VHV +      G + W     V+L    
Sbjct: 1155 DPHYRTFDGRLLHFQGSCSYVLAKDCHSGDFSVHVTNDDRGRSG-VAWTQEVAVLLG--D 1211

Query: 2103 LAHQVTIDRFNRKVTVDLQPVWPPVSRYGFR-IEDTGHMYMILTPSDIQIQWLHSSGLMI 2161
            +A ++  D     VTVD  PV  P  +     +E  GH  ++     +Q+ W    G   
Sbjct: 1212 MAVRLLQDG---AVTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLW---DGQSQ 1265

Query: 2162 VEASKTSKAQGH--GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSL----- 2214
            VE S     QG   GLCG  +G A +DL   +G ++      A F +SWQV   L     
Sbjct: 1266 VEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLL---PSEAAFGNSWQVSEGLWPGRP 1322

Query: 2215 TSVGQTRFRPDSC------ATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRD----- 2263
             S G+     D C      A  + +    ++ +  FS CH  VPPE F    + D     
Sbjct: 1323 CSAGR---EVDPCRAAGYRARREANARCGVLKSSPFSRCHAVVPPEPFFAACVYDLCACG 1379

Query: 2264 --TKYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSDS--TYQACVTACEPPKTC 2319
              +      C AL  Y + C +  V   WR    C   C  +    +  C   C  P+TC
Sbjct: 1380 PGSSADACLCDALEAYASHCRQAGVTPTWRGPTLCVVGCPLERGFVFDECGPPC--PRTC 1437

Query: 2320 --QDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKC 2361
              Q   LG L     +    GC C  G + H  H   CIP   C
Sbjct: 1438 FNQHIPLGELAAHCVRPCVPGCQCPAGLVEHEAH---CIPPEAC 1478



 Score = 58.5 bits (140), Expect = 9e-08
 Identities = 66/231 (28%), Positives = 80/231 (34%), Gaps = 47/231 (20%)

Query: 720 CGRTCQDLASPEACGVDGG------DDLSRDECVEGCA------CPPDTYLDTQADLCVP 767
           C   C D    E   VDG       D      C EG A      CP           C P
Sbjct: 477 CCPRCPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPLPGTCCP 536

Query: 768 RNQCSCHFQGVDYPPGDSDIPSLGH----CHCKDGVMSCDSRA------------PAAAC 811
            +   C F G +YP G +D P        C C  G + C +R             P   C
Sbjct: 537 NDCSGCAFGGKEYPSG-ADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECC 595

Query: 812 PAGQVFVNCSD------LHTDLELSRERTCEQQL-LNLSVSA-RGPCLSG-CACPQGLLR 862
           P       C         H +        C + L L+ SVS  R PC    CA P    R
Sbjct: 596 PQCPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHP----R 651

Query: 863 HGDACFLPEECPCTWKGKEYFPGDQVMSP---CHTCVCQRGSFQCTLHPCA 910
            G  C  P    C ++GKE+  G++  SP   CH C+C  GS  C    CA
Sbjct: 652 QGPCC--PSCDGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACA 700



 Score = 55.8 bits (133), Expect = 6e-07
 Identities = 61/242 (25%), Positives = 84/242 (34%), Gaps = 55/242 (22%)

Query: 715 PCVAPC---GRTCQDLASPEACGVDG-------------GDDLSRDECVEGCA------C 752
           PC  P    G  C    +P  C   G             GD   R  C++G        C
Sbjct: 583 PCPEPVLLPGECCPQCPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPC 642

Query: 753 PPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCH---CKDGVMSCDSRAPAA 809
           PP      +   C P     C +QG ++  G+        CH   C +G +SC+ +A A 
Sbjct: 643 PPAPCAHPRQGPCCPSCD-GCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAP 701

Query: 810 A----------CP-------AGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLS 852
           A          CP        G+ +++  +     E     TC   L       R PC  
Sbjct: 702 ALCPFPARGDCCPDCDGCEYLGESYLSNQEFPDPREPCNLCTC---LGGFVTCGRRPCEP 758

Query: 853 -GCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSP----CHTCVCQRGSFQCTLH 907
            GC+ P  L+  G  C  P    C + G     G+ +  P    C  C CQ GS +C   
Sbjct: 759 PGCSHP--LIPSGHCC--PTCQGCRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKK 814

Query: 908 PC 909
           PC
Sbjct: 815 PC 816



 Score = 50.8 bits (120), Expect = 2e-05
 Identities = 53/182 (29%), Positives = 67/182 (36%), Gaps = 39/182 (21%)

Query: 707  CEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCV 766
            C A +E  PC A   R  ++  +   CGV      SR   V     PP+ +       CV
Sbjct: 1323 CSAGREVDPCRAAGYRARREANA--RCGVLKSSPFSRCHAV----VPPEPFFAA----CV 1372

Query: 767  PRNQCSCHFQGVDYPPGDS------DIPSLGHCHCKDGVMSCDSRAPA---AACPA--GQ 815
              + C+C        PG S      D       HC+   ++   R P      CP   G 
Sbjct: 1373 -YDLCACG-------PGSSADACLCDALEAYASHCRQAGVTPTWRGPTLCVVGCPLERGF 1424

Query: 816  VFVNCSDLHTDLELSRERTCEQQ---LLNLSVSARGPCLSGCACPQGLLRHGDACFLPEE 872
            VF  C            RTC  Q   L  L+     PC+ GC CP GL+ H   C  PE 
Sbjct: 1425 VFDECGP-------PCPRTCFNQHIPLGELAAHCVRPCVPGCQCPAGLVEHEAHCIPPEA 1477

Query: 873  CP 874
            CP
Sbjct: 1478 CP 1479



 Score = 50.4 bits (119), Expect = 2e-05
 Identities = 83/312 (26%), Positives = 106/312 (33%), Gaps = 72/312 (23%)

Query: 619 SGSPL---DPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQPC 675
           SG P+   DPC  H + A+ SVQ C  L      PC     PVP    CR      GQ C
Sbjct: 261 SGEPVGSGDPCS-HCRCANGSVQ-CEPL------PCP----PVP----CRHPGKIPGQCC 304

Query: 676 -LCATLAHYAHLCRRHGLPVDFRARLPACALSC-----EASKEYSPC-VAPCGRTCQDLA 728
            +C    +  H   ++     FR +     + C     E S E   C V PC        
Sbjct: 305 PVCDGCEYQGH---QYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPCALPASGRQ 361

Query: 729 SPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIP 788
              AC +DG      +E  EG    PD           P   C C             +P
Sbjct: 362 LCPACELDG------EEFAEGVQWEPDGR---------PCTACVCQ----------DGVP 396

Query: 789 SLGHCHCKDGVMSCDSRAPAAACPA-------GQVFVNCSDLHTDLELSRERTCEQQLLN 841
             G   C        ++ P A CP+        QV+ N  +  TD + S    C  Q   
Sbjct: 397 KCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNF-TDAD-SPCHACHCQDGT 454

Query: 842 LSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMS----PCHTCVC 897
           ++ S      + CA PQ     G  C     CP     +E F   +  S    PC  C C
Sbjct: 455 VTCSLVDCPPTTCARPQS--GPGQCC---PRCPDCILEEEVFVDGESFSHPRDPCQECRC 509

Query: 898 QRGSFQCTLHPC 909
           Q G   C   PC
Sbjct: 510 QEGHAHCQPRPC 521



 Score = 48.1 bits (113), Expect = 1e-04
 Identities = 53/215 (24%), Positives = 73/215 (33%), Gaps = 45/215 (20%)

Query: 735 VDGGDDLSRDECVEGCA------CPPDTYLDTQADLCVPRNQC----SCHFQGVDYPPGD 784
           V  GD  S   C  G        CPP   +  +    +P   C     C +QG  Y   +
Sbjct: 265 VGSGDPCSHCRCANGSVQCEPLPCPP---VPCRHPGKIPGQCCPVCDGCEYQGHQYQSQE 321

Query: 785 S-DIPSLG---HCHCKDGVMSCDSRAPAAACPAGQVFVNCS--DLHTDLELSRERTCEQQ 838
           +  +   G    C C+ G +SC+ +     CP     +  S   L    EL  E   E  
Sbjct: 322 TFRLQERGLCVRCSCQAGEVSCEEQE----CPVTPCALPASGRQLCPACELDGEEFAE-- 375

Query: 839 LLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECP---------------CTWKGKEYF 883
              +     G   + C C  G+ + G     P  C                CT+  + Y 
Sbjct: 376 --GVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYA 433

Query: 884 PGDQVM---SPCHTCVCQRGSFQCTLHPCASTCTA 915
            G       SPCH C CQ G+  C+L  C  T  A
Sbjct: 434 NGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCA 468



 Score = 46.2 bits (108), Expect = 5e-04
 Identities = 37/128 (28%), Positives = 49/128 (38%), Gaps = 17/128 (13%)

Query: 793 CHCKDGVMSCDSRAPAAACPA----GQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARG 848
           C C+DG   C  +A    C      GQ + N      D       TC  + L  +V  +G
Sbjct: 117 CVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACT----TC--RCLTGAVQCQG 170

Query: 849 PCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSP---CHTCVCQRGSFQCT 905
           P  S   C +     G+ C +   C CT  G  +  G +  +P   C  C C  G  QC 
Sbjct: 171 PSCSELNCLESCTPPGECCPI---C-CTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCR 226

Query: 906 LHPCASTC 913
              CAS C
Sbjct: 227 QRECASLC 234



 Score = 44.7 bits (104), Expect = 0.001
 Identities = 92/389 (23%), Positives = 121/389 (31%), Gaps = 116/389 (29%)

Query: 2326 PLDPEHCQVLGEGCVCSEGTILHRRHS---ALCIPEAK-------CACTDSMGVPRALGE 2375
            PLDP  C +    C C EG++  ++     ALC   +        C    S G     GE
Sbjct: 794  PLDPT-CSL----CTCQEGSMRCQKKPCPPALCPHPSPGPCFCPVCHSCLSQGREHQDGE 848

Query: 2376 TWNSSLSGCCQHQCQAPDTIVPVDLGCPS--------------PRPESCLRFGEV----A 2417
             +      C   +CQA   +  V L CP               PR   CL  GE     +
Sbjct: 849  EFEGPAGSCEWCRCQAGQ-VSCVRLQCPPLPCKLQVTERGSCCPRCRGCLAHGEEHPEGS 907

Query: 2418 LLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYS----------- 2466
              +P    C   + CVC++ +       C            D CCP  S           
Sbjct: 908  RWVPPDSAC---SSCVCHEGVVTCARIQCISSCAQPRQGPHD-CCPQCSDCEHEGRKYEP 963

Query: 2467 -------------CECDPD-------LCEAELVPS---CRQDQILITGRLGDSCCTSYFC 2503
                         C C+P         C     PS   C   Q+L  G     CC +   
Sbjct: 964  GESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQLLPPGP--QHCCPTCAE 1021

Query: 2504 ACGDCPDSIP-------------ECQEGEALTVHRNTTELCCPLYQ------CVCENFRC 2544
            A  +C + +              +CQ+   L +H+   EL CPL +        C   R 
Sbjct: 1022 ALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIHQACPELSCPLSERHTPPGSCCPVCRA 1081

Query: 2545 PQVQC---GLGTALVEVWSPDRCCPYKSCECDCDTIPVPRCHLWEKSQLDEEFMHSVENV 2601
            P   C   G   A  E W+ D C    SC C   T+   RC     S L           
Sbjct: 1082 PTQSCVHQGREVASGERWTVDTC---TSCSCMAGTV---RCQSQRCSPLS---------- 1125

Query: 2602 CGCAKYECVK----APVCLSRELGVMQPG 2626
            CG  K   +      P CL R    M  G
Sbjct: 1126 CGPDKAPALSPGSCCPRCLPRPASCMAFG 1154



 Score = 42.0 bits (97), Expect = 0.009
 Identities = 130/604 (21%), Positives = 178/604 (29%), Gaps = 164/604 (27%)

Query: 2224 PDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAMCHK 2283
            P +C   DCS C      + + +   F  P   C L    +  VQ  C+A       C +
Sbjct: 531  PGTCCPNDCSGCA--FGGKEYPSGADFPHPSDPCRLCRCLSGNVQ--CLARRCVPLPCPE 586

Query: 2284 FHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTC-QDGILGPLDPEHCQVLGEGC--- 2339
                         P L   +     C   C  P  C + G       E+    G+ C   
Sbjct: 587  -------------PVLLPGE-----CCPQCPAPAGCPRPGAAHARHQEYFSPPGDPCRRC 628

Query: 2340 VCSEGTILHRRHSALCIPEAKCA------CTDS------MGVPRALGETWNSSLSGCCQH 2387
            +C +G++  +R   L  P A CA      C  S       G   A GE + S  + C  H
Sbjct: 629  LCLDGSVSCQR---LPCPPAPCAHPRQGPCCPSCDGCLYQGKEFASGERFPSPTAAC--H 683

Query: 2388 QCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCC--------LGTVCVCNQTLC 2439
             C   +       G  S  P++C          P +  CC        LG   + NQ   
Sbjct: 684  LCLCWE-------GSVSCEPKAC---APALCPFPARGDCCPDCDGCEYLGESYLSNQEF- 732

Query: 2440 EGLAPTCRPGHRLLTHFQEDSCCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCT 2499
                P  R    L T       C    CE  P  C   L+PS               CC 
Sbjct: 733  ----PDPREPCNLCTCLGGFVTCGRRPCE--PPGCSHPLIPS-------------GHCCP 773

Query: 2500 SYFCACGDCPDSIPECQEGEALTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVW 2559
            +    C  C         GE L    + T   C L  C   + RC +  C          
Sbjct: 774  T----CQGCRYHGVTTASGETLPDPLDPT---CSLCTCQEGSMRCQKKPC---------- 816

Query: 2560 SPDRCCPYKSC-ECDCDTIPVPRCHLWEKSQLDEEFMHSVENVCG-------------CA 2605
             P   CP+ S   C C     P CH       + +     E   G             C 
Sbjct: 817  -PPALCPHPSPGPCFC-----PVCHSCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCV 870

Query: 2606 KYECVKAPV---------CLSRELGVMQPGQTVVELSA----DGVCHTSRCTTVLDPLTN 2652
            + +C   P          C  R  G +  G+   E S     D  C +  C   +     
Sbjct: 871  RLQCPPLPCKLQVTERGSCCPRCRGCLAHGEEHPEGSRWVPPDSACSSCVCHEGV----- 925

Query: 2653 FYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTTSLFLPGASWIAD 2712
               +    + C   C   Q  + P D    C  C +    +         F PGA     
Sbjct: 926  ---VTCARIQCISSCA--QPRQGPHDCCPQCSDCEHEGRKYE----PGESFQPGADPCEV 976

Query: 2713 CARHHCSSTPLGAVLVR-------SPISCPPLNETECAKVGGSVVPSLEGCCRTCKEDGR 2765
            C    C   P G   +R       S + CPP            + P  + CC TC E   
Sbjct: 977  CI---CEPQPEGPPSLRCHRRQCPSLVGCPPSQ---------LLPPGPQHCCPTCAEALS 1024

Query: 2766 SCKK 2769
            +C +
Sbjct: 1025 NCSE 1028



 Score = 42.0 bits (97), Expect = 0.009
 Identities = 66/278 (23%), Positives = 89/278 (32%), Gaps = 50/278 (17%)

Query: 659 PYFEQCRRDACRCGQ------PCLCATLAH--------YAHLCRRHGLPVDFRARLPACA 704
           P  + CRR  C  G       PC  A  AH            C   G       R P+  
Sbjct: 620 PPGDPCRRCLCLDGSVSCQRLPCPPAPCAHPRQGPCCPSCDGCLYQGKEFASGERFPSPT 679

Query: 705 LSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQA-- 762
            +C     +   V+   + C    +P  C      D   D   +GC    ++YL  Q   
Sbjct: 680 AACHLCLCWEGSVSCEPKAC----APALCPFPARGDCCPD--CDGCEYLGESYLSNQEFP 733

Query: 763 DLCVPRNQCSCHFQGVDY------PPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQV 816
           D   P N C+C    V        PPG S  P +   HC      C  R       +G+ 
Sbjct: 734 DPREPCNLCTCLGGFVTCGRRPCEPPGCSH-PLIPSGHCCPTCQGC--RYHGVTTASGET 790

Query: 817 FVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDA--CFLPEECP 874
             +  D    L      TC++  +               CP  L  H     CF P    
Sbjct: 791 LPDPLDPTCSL-----CTCQEGSMRCQKKP---------CPPALCPHPSPGPCFCPVCHS 836

Query: 875 CTWKGKEYFPGDQVMSP---CHTCVCQRGSFQCTLHPC 909
           C  +G+E+  G++   P   C  C CQ G   C    C
Sbjct: 837 CLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQC 874



 Score = 39.3 bits (90), Expect = 0.056
 Identities = 62/242 (25%), Positives = 85/242 (35%), Gaps = 60/242 (24%)

Query: 2214 LTSVGQTRFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVA 2273
            ++S  Q R  P  C    CS C      R +     F P    CE+ I + +    P + 
Sbjct: 934  ISSCAQPRQGPHDCCP-QCSDCEH--EGRKYEPGESFQPGADPCEVCICEPQPEGPPSLR 990

Query: 2274 LTVYVAMCHKFHVCIEWRRSDYCPFLCSSDSTY-------QACVTACEPPKTCQDGILG- 2325
                   CH+            CP L     +          C T  E    C +G+LG 
Sbjct: 991  -------CHRRQ----------CPSLVGCPPSQLLPPGPQHCCPTCAEALSNCSEGLLGS 1033

Query: 2326 ---PLDPEH---CQVLGEGCV---CSEGTI-LHRRHS--ALCIPEAKCACTDSMGVPR-- 2371
               P DP +   CQ L   C+   C E +  L  RH+    C P  +      +   R  
Sbjct: 1034 ELAPPDPCYTCQCQDLTWLCIHQACPELSCPLSERHTPPGSCCPVCRAPTQSCVHQGREV 1093

Query: 2372 ALGETWN-------SSLSGCCQHQCQ-------APDTIVPVDLG--CPS--PRPESCLRF 2413
            A GE W        S ++G  + Q Q        PD    +  G  CP   PRP SC+ F
Sbjct: 1094 ASGERWTVDTCTSCSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPASCMAF 1153

Query: 2414 GE 2415
            G+
Sbjct: 1154 GD 1155



 Score = 37.7 bits (86), Expect = 0.16
 Identities = 56/248 (22%), Positives = 74/248 (29%), Gaps = 81/248 (32%)

Query: 668 ACRCGQPCL-CATLAHYAHL--CRRHGLPV-DFRARLPACALSCEASKEYSPCVAPCGRT 723
           AC C      C   AH  H   C ++G    +     P    +C        C  P   +
Sbjct: 116 ACVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLTGAVQCQGP---S 172

Query: 724 CQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPG 783
           C +L   E+C   G       EC   C     ++ +   +   P + C            
Sbjct: 173 CSELNCLESCTPPG-------ECCPICCTEGGSHWEHGQEWTTPGDPCRI---------- 215

Query: 784 DSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLS 843
                    C C +G + C  R  A+ CP                               
Sbjct: 216 ---------CRCLEGHIQCRQRECASLCP------------------------------- 235

Query: 844 VSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMS--PCHTCVCQRGS 901
             AR   L G  CP       D CFL         G+E+  G+ V S  PC  C C  GS
Sbjct: 236 YPARP--LPGTCCPV-----CDGCFL--------NGREHRSGEPVGSGDPCSHCRCANGS 280

Query: 902 FQCTLHPC 909
            QC   PC
Sbjct: 281 VQCEPLPC 288



 Score = 36.6 bits (83), Expect = 0.36
 Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 8/74 (10%)

Query: 852 SGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSP--CHTCVCQRGSFQCTLHPC 909
           + C C  G    G    LP    C+  G+ Y  G +  SP  C TC C  G+ QC    C
Sbjct: 115 TACVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNG-ETFSPDACTTCRCLTGAVQCQGPSC 173

Query: 910 A-----STCTAYGD 918
           +      +CT  G+
Sbjct: 174 SELNCLESCTPPGE 187



 Score = 36.6 bits (83), Expect = 0.36
 Identities = 28/97 (28%), Positives = 34/97 (35%), Gaps = 5/97 (5%)

Query: 350 KAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTL 409
           K F   E      A+CH    C +  ++C      P    F   G   P    CE+ G  
Sbjct: 667 KEFASGERFPSPTAACH-LCLCWEGSVSCEPKACAPALCPFPARGDCCPDCDGCEYLGES 725

Query: 410 YPPGSVV---KEDCNTCTCTSGKWECSTAVC-PAECS 442
           Y         +E CN CTC  G   C    C P  CS
Sbjct: 726 YLSNQEFPDPREPCNLCTCLGGFVTCGRRPCEPPGCS 762



 Score = 36.2 bits (82), Expect = 0.48
 Identities = 53/202 (26%), Positives = 70/202 (34%), Gaps = 44/202 (21%)

Query: 257 LPRPPCLQQNPGTMQGVYEQCEALLRPPFDAC----HAYVSPLPFTAS----CTSDLCQS 308
           LP PP   ++PG + G   QC     P  D C    H Y S   F       C    CQ+
Sbjct: 286 LPCPPVPCRHPGKIPG---QC----CPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQA 338

Query: 309 MGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPR 368
            G+V+  C         CA    P  G     RQ    C+     + E +   P    P 
Sbjct: 339 -GEVS--CEEQECPVTPCAL---PASG-----RQLCPACELDGEEFAEGVQWEPDG-RPC 386

Query: 369 ASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE-----CP----CEFHGTLYPPGSVVKE- 418
            +CV     C DG      ++     C  P +     CP    C +H  +Y  G    + 
Sbjct: 387 TACV-----CQDGVPKCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDA 441

Query: 419 --DCNTCTCTSGKWECSTAVCP 438
              C+ C C  G   CS   CP
Sbjct: 442 DSPCHACHCQDGTVTCSLVDCP 463



 Score = 35.4 bits (80), Expect = 0.81
 Identities = 88/382 (23%), Positives = 121/382 (31%), Gaps = 111/382 (29%)

Query: 2309 CVTACEPPKTC------------QDGILGPLDPEHCQVLGEGCVCSEGTILHRRH--SAL 2354
            C+ +C PP  C            + G       + C++    C C EG I  R+   ++L
Sbjct: 178  CLESCTPPGECCPICCTEGGSHWEHGQEWTTPGDPCRI----CRCLEGHIQCRQRECASL 233

Query: 2355 C------IPEAKCACTDSM---GVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSP 2405
            C      +P   C   D     G     GE   S     C H   A  ++    L CP  
Sbjct: 234  CPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSG--DPCSHCRCANGSVQCEPLPCP-- 289

Query: 2406 RPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSY 2465
             P  C   G++         CC     VC+    +G     +   RL    QE   C   
Sbjct: 290  -PVPCRHPGKIP------GQCCP----VCDGCEYQGHQYQSQETFRL----QERGLCVRC 334

Query: 2466 SCECDPDLCEAE---------------LVPSCRQD--------QILITGRLGDSC----- 2497
            SC+     CE +               L P+C  D        Q    GR   +C     
Sbjct: 335  SCQAGEVSCEEQECPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTACVCQDG 394

Query: 2498 ---CTSYFCACGDC--PDSIPE--CQEGEALTVH-------RNTTELCCPLYQCVCEN-- 2541
               C +  C    C  P   P   C   ++ T H       +N T+   P + C C++  
Sbjct: 395  VPKCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADSPCHACHCQDGT 454

Query: 2542 FRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVPRCHLWEKSQLD-EEFMH---- 2596
              C  V C   T       P +CCP     C       P C L E+  +D E F H    
Sbjct: 455  VTCSLVDCPPTTCARPQSGPGQCCP----RC-------PDCILEEEVFVDGESFSHPRDP 503

Query: 2597 -----SVENVCGCAKYECVKAP 2613
                   E    C    C +AP
Sbjct: 504  CQECRCQEGHAHCQPRPCPRAP 525



 Score = 33.5 bits (75), Expect = 3.1
 Identities = 42/181 (23%), Positives = 61/181 (33%), Gaps = 46/181 (25%)

Query: 300 SCTSDLCQSMGDVATWC--RALAEYARACAQAGRPLQGWRT-QLRQCT--------VHCK 348
           +CT+ +CQ   D A  C  +A   + R C+Q G+      T     CT        V C+
Sbjct: 113 ACTACVCQ---DGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLTGAVQCQ 169

Query: 349 EKAFTYNECIA-------CCPASCHPRAS-------------------CVDSEIACVD-- 380
             + +   C+        CCP  C    S                   C++  I C    
Sbjct: 170 GPSCSELNCLESCTPPGECCPICCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRE 229

Query: 381 -GCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVK--EDCNTCTCTSGKWECSTAVC 437
               CP       G C  P    C  +G  +  G  V   + C+ C C +G  +C    C
Sbjct: 230 CASLCPYPARPLPGTC-CPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPC 288

Query: 438 P 438
           P
Sbjct: 289 P 289



 Score = 33.5 bits (75), Expect = 3.1
 Identities = 25/84 (29%), Positives = 33/84 (39%), Gaps = 12/84 (14%)

Query: 1340 YDACASPCFQTCRDPR------AASCRDVPRVEGCVPVCPTPQVLDEVTQRCVYLEDCVE 1393
            +D C  PC +TC +        AA C     V  CVP C  P  L E    C+  E C +
Sbjct: 1426 FDECGPPCPRTCFNQHIPLGELAAHC-----VRPCVPGCQCPAGLVEHEAHCIPPEACPQ 1480

Query: 1394 PAVWVPTEALGNETLPPSQGLPTP 1417
              +    + LG    P  +   TP
Sbjct: 1481 -VLLTGDQPLGARPSPSREPQETP 1503



 Score = 33.1 bits (74), Expect = 4.0
 Identities = 21/76 (27%), Positives = 26/76 (34%), Gaps = 19/76 (25%)

Query: 382 CYCPNGLIF------EDGGCVAPAE-----CP----CEFHGTLYPPGSVVKED----CNT 422
           C C  G +       E  GC  P       CP    C +HG     G  + +     C+ 
Sbjct: 742 CTCLGGFVTCGRRPCEPPGCSHPLIPSGHCCPTCQGCRYHGVTTASGETLPDPLDPTCSL 801

Query: 423 CTCTSGKWECSTAVCP 438
           CTC  G   C    CP
Sbjct: 802 CTCQEGSMRCQKKPCP 817



 Score = 32.7 bits (73), Expect = 5.3
 Identities = 40/152 (26%), Positives = 53/152 (34%), Gaps = 20/152 (13%)

Query: 301 CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 360
           CT+ +CQ   D    C A+      C    +P          CT H +  A   N   A 
Sbjct: 386 CTACVCQ---DGVPKCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDAD 442

Query: 361 CPA-SCHPRASCVDSEIAC--VDGCYCPNGLIF--EDGGCVAPAECP-CEFHGTLYPPG- 413
            P  +CH    C D  + C  VD   CP       + G       CP C     ++  G 
Sbjct: 443 SPCHACH----CQDGTVTCSLVD---CPPTTCARPQSGPGQCCPRCPDCILEEEVFVDGE 495

Query: 414 --SVVKEDCNTCTCTSGKWECSTAVCP-AECS 442
             S  ++ C  C C  G   C    CP A C+
Sbjct: 496 SFSHPRDPCQECRCQEGHAHCQPRPCPRAPCA 527



 Score = 32.7 bits (73), Expect = 5.3
 Identities = 25/90 (27%), Positives = 30/90 (33%), Gaps = 17/90 (18%)

Query: 356 ECIA--CCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPG 413
           +C+A  C P  C P    +  E  C   C  P        GC  P            PPG
Sbjct: 573 QCLARRCVPLPC-PEPVLLPGE--CCPQCPAP-------AGCPRPGAAHARHQEYFSPPG 622

Query: 414 SVVKEDCNTCTCTSGKWECSTAVC-PAECS 442
               + C  C C  G   C    C PA C+
Sbjct: 623 ----DPCRRCLCLDGSVSCQRLPCPPAPCA 648



 Score = 32.0 bits (71), Expect = 9.0
 Identities = 27/92 (29%), Positives = 37/92 (40%), Gaps = 17/92 (18%)

Query: 362 PASCHPRASCVDSEIACVDGCYCP----NGLIFEDGGCVAPAECP----CEFHGTLYPPG 413
           PA       C   +++CV    CP       + E G C     CP    C  HG  +P G
Sbjct: 853 PAGSCEWCRCQAGQVSCVR-LQCPPLPCKLQVTERGSC-----CPRCRGCLAHGEEHPEG 906

Query: 414 SV-VKED--CNTCTCTSGKWECSTAVCPAECS 442
           S  V  D  C++C C  G   C+   C + C+
Sbjct: 907 SRWVPPDSACSSCVCHEGVVTCARIQCISSCA 938


>gi|239757284 PREDICTED: similar to Fc fragment of IgG binding protein
            [Homo sapiens]
          Length = 593

 Score =  147 bits (371), Expect = 1e-34
 Identities = 143/565 (25%), Positives = 215/565 (38%), Gaps = 79/565 (13%)

Query: 546  VRTNVGVRVLYDREGLRLYLQVDQ--RWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQL 603
            + T+ G+RV YD   L  Y++V     + +   GLCG +NG+ +DDF  P G        
Sbjct: 23   IETDFGLRVAYD---LVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANE 79

Query: 604  FGNSWKTLSACSPLVSGSPLDP----------CDVHLQAASYSVQACSVLTGEM--FAPC 651
            FGNSW+ +   SP +  +P  P          C   L+      + C +L+      + C
Sbjct: 80   FGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSC 139

Query: 652  SAFLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEA 709
               + P    + C  D C  G     LC+ +  Y   C+  G  V+       C + C  
Sbjct: 140  HKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPP 199

Query: 710  SKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRN 769
            +  Y  C   C   C  L++P  C         +D C EGC C      + QA  CVP  
Sbjct: 200  NSHYELCADTCSLGCSALSAPPQC---------QDGCAEGCQCDSGFLYNGQA--CVPIQ 248

Query: 770  QCSCHFQGVDYPPGDSDI--PSLGHCHCKDG-VMSCDSRAPAAACPAGQVFVNCSDLHTD 826
            QC C+  GV Y P  + +       C C  G V+ C       +C  GQV      +   
Sbjct: 249  QCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEH----SCKPGQVCQPSGGI--- 301

Query: 827  LELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGD--ACFLPEECPCTWKGKEYFP 884
                   +C  ++   S++  G  + G A    +L +G      LP   P    G     
Sbjct: 302  ------LSCVTKVTLRSLAQTGVDVEGAA----ILYNGQPLKVLLPLLSPDPCHG----- 346

Query: 885  GDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHL----- 939
                  P  TC  Q G   C L    +TC  +GD HY +FDG  FDF G C   L     
Sbjct: 347  --VTCRPQETCKEQGGQGVC-LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGC 403

Query: 940  --VKSTSDVSFSVIVENVNCYSSGMICRKFISI-NVGNSLIVFDDDSG--------NPSP 988
              V +     F+V  +N N  +  +   + +++  +G ++ +  D+ G           P
Sbjct: 404  PGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALP 463

Query: 989  ESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLK 1048
             S  D +  V         +  F    + + +D    V V     + G + GLCGN D  
Sbjct: 464  VSVADGRISVTQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRN 520

Query: 1049 TINEMRTPENLELTNPQEFGSSWAA 1073
              N+   P      +   +G SW A
Sbjct: 521  PNNDQVFPNGTLAPSIPIWGGSWRA 545



 Score =  129 bits (323), Expect = 5e-29
 Identities = 84/285 (29%), Positives = 128/285 (44%), Gaps = 20/285 (7%)

Query: 160 VQLPHVM--GSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNA 217
           ++LP V+  G  R  Q    V++       +A+D    V + +         GLCGN N 
Sbjct: 1   MKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNG 60

Query: 218 DPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPP----CLQQN--PGTMQ 271
           DPKDD    +G    +  EF +SW+E  P+ P  P T   P PP    C+  +  P  ++
Sbjct: 61  DPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPT---PCPPGSEDCIPSHKCPPELE 117

Query: 272 GVYEQ---CEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARAC 326
             Y++   C  L  P  P  +CH  V P      C  DLC   G+++  C  +  Y  AC
Sbjct: 118 KKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSAC 177

Query: 327 AQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPN 386
             AG  ++ WRT+   C + C   +  Y  C   C   C   ++    +  C +GC C +
Sbjct: 178 QAAGGHVEPWRTE-TFCPMECPPNSH-YELCADTCSLGCSALSAPPQCQDGCAEGCQCDS 235

Query: 387 GLIFEDGGCVAPAECPCEFHGTLY-PPGSVVKEDC-NTCTCTSGK 429
           G ++    CV   +C C  +G  Y P  +V+ ++C   CTC +GK
Sbjct: 236 GFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGK 280



 Score = 67.0 bits (162), Expect = 3e-10
 Identities = 88/345 (25%), Positives = 125/345 (36%), Gaps = 74/345 (21%)

Query: 2174 GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQ--VPSSLTSVGQTRFRP---DSCA 2228
            GLCG  +GD  +D    +GS  G A +   F +SW+  VP S   +  T   P   D   
Sbjct: 53   GLCGNYNGDPKDDFQKPNGSQAGNANE---FGNSWEEVVPDS-PCLPPTPCPPGSEDCIP 108

Query: 2229 TTDCSPCLR----------MVSNRT--FSACHRFVPPESFCELWIRDTKY----VQQPCV 2272
            +  C P L           ++S+ T   S+CH+ V P+   +  I D       +   C 
Sbjct: 109  SHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCS 168

Query: 2273 ALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTAC-------EPPKTCQDGIL 2324
             +  YV+ C      +E WR   +CP  C  +S Y+ C   C         P  CQDG  
Sbjct: 169  NIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDG-- 226

Query: 2325 GPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGC 2384
                        EGC C  G +    +   C+P  +C C  + GV     E   + L   
Sbjct: 227  ----------CAEGCQCDSGFLY---NGQACVPIQQCGCYHN-GV---YYEPEQTVLIDN 269

Query: 2385 CQHQ--CQAPDTIVPVDLGC-------PSPRPESCLRFGEVALLLPTKDPCCLGTVCVCN 2435
            C+ Q  C A   +V  +  C       PS    SC+    +  L  T        +    
Sbjct: 270  CRQQCTCHAGKVVVCQEHSCKPGQVCQPSGGILSCVTKVTLRSLAQTGVDVEGAAILYNG 329

Query: 2436 QTL-----------CEGLAPTCRPGHRLLTHFQEDSCCPSYSCEC 2469
            Q L           C G+  TCRP         +  C P+Y   C
Sbjct: 330  QPLKVLLPLLSPDPCHGV--TCRPQETCKEQGGQGVCLPNYEATC 372



 Score = 66.6 bits (161), Expect = 3e-10
 Identities = 47/162 (29%), Positives = 70/162 (43%), Gaps = 20/162 (12%)

Query: 1026 VHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAV----------E 1075
            V V     +  Q+ GLCGN++    ++ + P   +  N  EFG+SW  V           
Sbjct: 39   VRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTP 98

Query: 1076 CP---DTLDPRDMCVLNPLREPFAKKE-CSILLSEV--FEICHPVVDVTWFYSNCLTDTC 1129
            CP   +   P   C    L + + K+E C +L S       CH +VD      +C+ D  
Sbjct: 99   CPPGSEDCIPSHKCP-PELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDL- 156

Query: 1130 GCSQGGDCECFCASVSAYAHQCCQHGVAVD-WRTPRLCPYDC 1170
             C  GG+    C+++ AY   C   G  V+ WRT   CP +C
Sbjct: 157  -CLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMEC 197



 Score = 46.6 bits (109), Expect = 4e-04
 Identities = 45/188 (23%), Positives = 78/188 (41%), Gaps = 13/188 (6%)

Query: 73  PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS-----FSIQVHNDPQCG 127
           P  ++ C  WG  H  +FDG  +   G  +Y L     P   +     F++   N  + G
Sbjct: 366 PNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNR-G 424

Query: 128 SSPYTCSRAVSLFFVGEQ-EIHLAK--EVTHGGMRVQLPHVMGSARLQ--QLAGYVIVRH 182
           +   +  R V++  +G    IH  +  +V   G+   LP  +   R+   Q A   ++  
Sbjct: 425 NPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVA 484

Query: 183 QSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ 242
                +++D    V + +     G   GLCGN + +P +D V  +G L   +  +  SW 
Sbjct: 485 DFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSW- 543

Query: 243 EQAPNQPP 250
            +AP   P
Sbjct: 544 -RAPGWDP 550


>gi|37693519 BMP-binding endothelial regulator precursor protein
           [Homo sapiens]
          Length = 685

 Score =  145 bits (367), Expect = 4e-34
 Identities = 95/332 (28%), Positives = 142/332 (42%), Gaps = 10/332 (3%)

Query: 74  ERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTC 133
           E+  +C  +G  H  TFDG  +   G   Y L          F + V ND +   S ++ 
Sbjct: 359 EKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKNDARRTRS-FSW 417

Query: 134 SRAVSLFFVGEQEIHLAKEVT--HGGMRVQLPHVMGSARLQQLAGYVI-VRHQSAFTLAW 190
           +++V L  +GE  + L + +T    G R+ LP       +  L GY++ V  ++   ++W
Sbjct: 418 TKSVELV-LGESRVSLQQHLTVRWNGSRIALPCRAPHFHID-LDGYLLKVTTKAGLEISW 475

Query: 191 DGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPP 250
           DG S V +  +P L G   GLCGN N   +DDL+   G    DV +F  SW+ ++     
Sbjct: 476 DGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCN 535

Query: 251 GPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMG 310
            P     P P   Q         + +C+ L    F  CH+ V    F  SC +D+C+   
Sbjct: 536 RPQRK--PVPELCQGTVKVKLRAHRECQKLKSWEFQTCHSTVDYATFYRSCVTDMCECPV 593

Query: 311 DVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRAS 370
               +C +   Y RAC + G  +  W  Q       CK  A  Y+ C   C  +C     
Sbjct: 594 HKNCYCESFLAYTRACQREGIKVH-WEPQQNCAATQCKHGA-VYDTCGPGCIKTCDNWNE 651

Query: 371 CVDSEIACVDGCYCPNGLIFEDGGCVAPAECP 402
                  CV GC+CP  L+   G C+ P  CP
Sbjct: 652 IGPCNKPCVAGCHCPANLVLHKGRCIKPVLCP 683



 Score =  134 bits (338), Expect = 1e-30
 Identities = 112/453 (24%), Positives = 174/453 (38%), Gaps = 64/453 (14%)

Query: 345 VHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGC-------VA 397
           V+    +F Y+ C AC         +C DS + C   C  P G      GC       V 
Sbjct: 244 VYDNGSSFLYDNCTAC---------TCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVP 294

Query: 398 PAECP-CEFHGTLYPPGSVVKE-DCNTCTCTSGKWECSTAVC------------------ 437
           P +   C+F   ++  G +    +C  C C  G+ EC    C                  
Sbjct: 295 PEDIKVCKFGNKIFQDGEMWSSINCTICACVKGRTECRNKQCIPISSCPQGKILNRKGCC 354

Query: 438 ------PAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSS--GTFTVTLQNAPCGLNQ 489
                 P  C+V GD H+ TFDGR + F  TCQY+L K  SS    F V ++N      +
Sbjct: 355 PICTEKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKN-DARRTR 413

Query: 490 DGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTN 549
             +  +SV ++L +    +V+L Q   V  ++  +I  P     F I  L    L+V T 
Sbjct: 414 SFSWTKSVELVLGES---RVSLQQHLTV-RWNGSRIALPCRAPHFHI-DLDGYLLKVTTK 468

Query: 550 VGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWK 609
            G+ + +D +   + +           GLCG +NG+ +DD +   G  +     F  SW+
Sbjct: 469 AGLEISWDGDSF-VEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWR 527

Query: 610 TLS--ACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRD 667
             S   C+        + C   ++    + + C  L    F  C + +    ++  C  D
Sbjct: 528 VESNEFCNRPQRKPVPELCQGTVKVKLRAHRECQKLKSWEFQTCHSTVDYATFYRSCVTD 587

Query: 668 ACRC--GQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQ 725
            C C   + C C +   Y   C+R G+ V +  +    A  C+    Y  C   C +TC 
Sbjct: 588 MCECPVHKNCYCESFLAYTRACQREGIKVHWEPQQNCAATQCKHGAVYDTCGPGCIKTCD 647

Query: 726 DLASPEACGVDGGDDLSRDECVEGCACPPDTYL 758
           +      C            CV GC CP +  L
Sbjct: 648 NWNEIGPC---------NKPCVAGCHCPANLVL 671



 Score =  122 bits (305), Expect = 7e-27
 Identities = 138/578 (23%), Positives = 205/578 (35%), Gaps = 104/578 (17%)

Query: 674  PCLCATLAHYAHLCRRHGLPVDFR------ARLPACALSCE----------ASKEYSPCV 717
            PC+     +    C+R   PV  R       +  AC   C+          +S ++    
Sbjct: 66   PCIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCKGCTYEGNTYNSSFKWQSPA 125

Query: 718  APCG-RTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQ 776
             PC  R CQ+    E+ GV          CV  C  P +        +C P     C F+
Sbjct: 126  EPCVLRQCQEGVVTES-GV---------RCVVHCKNPLE-----HLGMCCPTCP-GCVFE 169

Query: 777  GVDYPPGDSDIPS---LGHCHCKDGVMSCDSRA-PAAACPA-------GQVFVNC----- 820
            GV Y  G+   P       C C  G   C     P  +CP        GQ    C     
Sbjct: 170  GVQYQEGEEFQPEGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQCCPKCLGQRK 229

Query: 821  ------------SDLHTDLELSRERTCEQ-QLLNLSVSARGPCLSGCACPQGLLRHGDAC 867
                        SD++ +        C      + +V  +  C     C QG     + C
Sbjct: 230  VFDLPFGSCLFRSDVYDNGSSFLYDNCTACTCRDSTVVCKRKCSHPGGCDQGQEGCCEEC 289

Query: 868  FL---PEECPCTWKGKEYFPGDQVMSP--CHTCVCQRGSFQCTLHPCA------------ 910
             L   PE+      G + F   ++ S   C  C C +G  +C    C             
Sbjct: 290  LLRVPPEDIKVCKFGNKIFQDGEMWSSINCTICACVKGRTECRNKQCIPISSCPQGKILN 349

Query: 911  ------------STCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVS--FSVIVENVN 956
                          CT +GD HY TFDG  F+F G C+  L K  S  +  F V+V+N  
Sbjct: 350  RKGCCPICTEKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKNDA 409

Query: 957  CYSSGMICRKFISINVGNSLIVFDDD---SGNPSPESFLDDKQEVHTWRVGFFTLVHFPQ 1013
              +      K + + +G S +          N S  +        H    G+   V   +
Sbjct: 410  RRTRSFSWTKSVELVLGESRVSLQQHLTVRWNGSRIALPCRAPHFHIDLDGYLLKVT-TK 468

Query: 1014 EHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAA 1073
              + + WD  + V V A P  +G+L GLCGN++    +++   +     +  +F  SW  
Sbjct: 469  AGLEISWDGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRV 528

Query: 1074 VE---C--PDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDT 1128
                 C  P      ++C      +  A +EC  L S  F+ CH  VD   FY +C+TD 
Sbjct: 529  ESNEFCNRPQRKPVPELCQGTVKVKLRAHRECQKLKSWEFQTCHSTVDYATFYRSCVTDM 588

Query: 1129 CGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLC 1166
            C C    +  C+C S  AY   C + G+ V W   + C
Sbjct: 589  CECPVHKN--CYCESFLAYTRACQREGIKVHWEPQQNC 624



 Score = 66.6 bits (161), Expect = 3e-10
 Identities = 92/406 (22%), Positives = 154/406 (37%), Gaps = 71/406 (17%)

Query: 1986 DCVRHICLEGQLIRVNQS----QHCPQGAAPPRCGILGLAVRVGGDRCCPLW-ECACRCS 2040
            +C    C++G+    N+       CPQG    R G            CCP+  E    C+
Sbjct: 318  NCTICACVKGRTECRNKQCIPISSCPQGKILNRKG------------CCPICTEKPGVCT 365

Query: 2041 IFPDLSFVTFDGSHVALFKEAIYILSQ---SPDEMLTVHVLDCKSANLGHLNWPPFCLVM 2097
            +F D  + TFDG          Y+L++   SP     V V +  +      +W     ++
Sbjct: 366  VFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKN-DARRTRSFSWTKSVELV 424

Query: 2098 LNMTHLAHQ--VTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLH 2155
            L  + ++ Q  +T+     ++ +       P     F I+  G++  + T + ++I W  
Sbjct: 425  LGESRVSLQQHLTVRWNGSRIAL-------PCRAPHFHIDLDGYLLKVTTKAGLEISW-D 476

Query: 2156 SSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSS-L 2214
                + V A+   K +  GLCG  +G   +DL   DG+     +D   F +SW+V S+  
Sbjct: 477  GDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDD---FAESWRVESNEF 533

Query: 2215 TSVGQTRFRPDSCATT---------DCSPCLRMVSNRTFSACHRFVPPESF--------C 2257
             +  Q +  P+ C  T         +C    + + +  F  CH  V   +F        C
Sbjct: 534  CNRPQRKPVPELCQGTVKVKLRAHREC----QKLKSWEFQTCHSTVDYATFYRSCVTDMC 589

Query: 2258 ELWIRDTKYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFL-CSSDSTYQACVTACEPP 2316
            E  +    Y    C +   Y   C +  + + W     C    C   + Y  C   C   
Sbjct: 590  ECPVHKNCY----CESFLAYTRACQREGIKVHWEPQQNCAATQCKHGAVYDTCGPGC--I 643

Query: 2317 KTCQD-GILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKC 2361
            KTC +   +GP + + C     GC C    +LH+     CI    C
Sbjct: 644  KTCDNWNEIGPCN-KPCVA---GCHCPANLVLHK---GRCIKPVLC 682



 Score = 41.6 bits (96), Expect = 0.011
 Identities = 39/154 (25%), Positives = 55/154 (35%), Gaps = 12/154 (7%)

Query: 292 VSPLPFTASCTSDLCQSMGDVATWCRALAEY-ARACAQAGRPLQGWRTQLRQCTV--HCK 348
           V  +PF       +C  +    T  R      +R CA A +       Q + CT   +  
Sbjct: 56  VLQIPFITDNPCIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCKGCTYEGNTY 115

Query: 349 EKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECP-CEFHG 407
             +F +      C           +S + CV  C  P     E  G   P  CP C F G
Sbjct: 116 NSSFKWQSPAEPCVLRQCQEGVVTESGVRCVVHCKNP----LEHLGMCCPT-CPGCVFEG 170

Query: 408 TLYPPGSVVKED---CNTCTCTSGKWECSTAVCP 438
             Y  G   + +   C  C+CT G+ +C   VCP
Sbjct: 171 VQYQEGEEFQPEGSKCTKCSCTGGRTQCVREVCP 204



 Score = 34.7 bits (78), Expect = 1.4
 Identities = 12/26 (46%), Positives = 15/26 (57%)

Query: 849 PCLSGCACPQGLLRHGDACFLPEECP 874
           PC++GC CP  L+ H   C  P  CP
Sbjct: 658 PCVAGCHCPANLVLHKGRCIKPVLCP 683


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.134    0.440 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 134,243,724
Number of Sequences: 37866
Number of extensions: 7491852
Number of successful extensions: 49007
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 145
Number of HSP's successfully gapped in prelim test: 1651
Number of HSP's that attempted gapping in prelim test: 28019
Number of HSP's gapped (non-prelim): 11320
length of query: 2852
length of database: 18,247,518
effective HSP length: 120
effective length of query: 2732
effective length of database: 13,703,598
effective search space: 37438229736
effective search space used: 37438229736
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 71 (32.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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