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Search of human proteins with 239749578
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo
sapiens]
(1002 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 1965 0.0
gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 1942 0.0
gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 1942 0.0
gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 1850 0.0
gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 1848 0.0
gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 1848 0.0
gi|154354990 ankyrin repeat domain 26 [Homo sapiens] 521 e-147
gi|60460920 ankyrin repeat domain 20 family, member A3 [Homo sap... 369 e-102
gi|60115723 ankyrin repeat domain 20 family, member A2 [Homo sap... 369 e-102
gi|149363679 ankyrin repeat domain 20 family, member A4 [Homo sa... 368 e-101
gi|156104901 ankyrin repeat domain 20 family, member A1 [Homo sa... 367 e-101
gi|239757009 PREDICTED: ankyrin repeat domain 20 family, member ... 353 4e-97
gi|239751523 PREDICTED: ankyrin repeat domain 20 family, member ... 353 4e-97
gi|239756999 PREDICTED: ankyrin repeat domain 62 [Homo sapiens] 283 6e-76
gi|239751514 PREDICTED: ankyrin repeat domain 62 isoform 4 [Homo... 283 6e-76
gi|239746016 PREDICTED: ankyrin repeat domain 62 isoform 1 [Homo... 282 1e-75
gi|149363642 coiled-coil domain containing 144A [Homo sapiens] 268 2e-71
gi|239741279 PREDICTED: similar to FLJ00310 protein [Homo sapiens] 253 8e-67
gi|53828703 POTE ankyrin domain family, member A isoform 2 [Homo... 248 2e-65
gi|239745058 PREDICTED: hypothetical protein XP_002343353 [Homo ... 243 7e-64
gi|52856430 protein expressed in prostate, ovary, testis, and pl... 241 2e-63
gi|209977003 ANKRD26-like family C, member 3 [Homo sapiens] 241 2e-63
gi|52856434 POTE ankyrin domain family, member G [Homo sapiens] 240 4e-63
gi|239741769 PREDICTED: similar to protein expressed in prostate... 240 4e-63
gi|224282147 prostate-specific P704P [Homo sapiens] 240 6e-63
gi|134133226 protein expressed in prostate, ovary, testis, and p... 239 9e-63
gi|153791352 prostate, ovary, testis expressed protein on chromo... 239 1e-62
gi|113413200 PREDICTED: similar to protein expressed in prostate... 238 2e-62
gi|88953571 PREDICTED: similar to protein expressed in prostate,... 238 2e-62
gi|153792284 pote protein [Homo sapiens] 235 1e-61
>gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1002
Score = 1965 bits (5091), Expect = 0.0
Identities = 1002/1002 (100%), Positives = 1002/1002 (100%)
Query: 1 MRKLFSFGRRLGQALLSSMDQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRD 60
MRKLFSFGRRLGQALLSSMDQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRD
Sbjct: 1 MRKLFSFGRRLGQALLSSMDQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRD 60
Query: 61 LDARDRKDRTVLHLACAHGRVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVL 120
LDARDRKDRTVLHLACAHGRVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVL
Sbjct: 61 LDARDRKDRTVLHLACAHGRVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVL 120
Query: 121 LECGANPNIEDIYGNTALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQ 180
LECGANPNIEDIYGNTALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQ
Sbjct: 121 LECGANPNIEDIYGNTALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQ 180
Query: 181 HMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYA 240
HMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYA
Sbjct: 181 HMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYA 240
Query: 241 LCSDLRSIRQQILEHKNKMLKNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQ 300
LCSDLRSIRQQILEHKNKMLKNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQ
Sbjct: 241 LCSDLRSIRQQILEHKNKMLKNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQ 300
Query: 301 ERLQRSENKQPQDSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYIQEIK 360
ERLQRSENKQPQDSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYIQEIK
Sbjct: 301 ERLQRSENKQPQDSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYIQEIK 360
Query: 361 SITEINANFEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVE 420
SITEINANFEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVE
Sbjct: 361 SITEINANFEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVE 420
Query: 421 SLHSSLATAINEYNEIVERKDLELVLWRADDVSRHEKMGSNISQLTDKNELLTEQVHKAR 480
SLHSSLATAINEYNEIVERKDLELVLWRADDVSRHEKMGSNISQLTDKNELLTEQVHKAR
Sbjct: 421 SLHSSLATAINEYNEIVERKDLELVLWRADDVSRHEKMGSNISQLTDKNELLTEQVHKAR 480
Query: 481 VKFNTLKGKLRETRDALREKTLALGSVQLDLRQAQHRIKEMKQMHPNGEAKESQSIGKQN 540
VKFNTLKGKLRETRDALREKTLALGSVQLDLRQAQHRIKEMKQMHPNGEAKESQSIGKQN
Sbjct: 481 VKFNTLKGKLRETRDALREKTLALGSVQLDLRQAQHRIKEMKQMHPNGEAKESQSIGKQN 540
Query: 541 SLEERIRQQELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKELMKEY 600
SLEERIRQQELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKELMKEY
Sbjct: 541 SLEERIRQQELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKELMKEY 600
Query: 601 NYLKEKLLQCEKEKAEREVIVREFQEELVDHLKTFSISESPLEGTSHCHINLNETWTSKK 660
NYLKEKLLQCEKEKAEREVIVREFQEELVDHLKTFSISESPLEGTSHCHINLNETWTSKK
Sbjct: 601 NYLKEKLLQCEKEKAEREVIVREFQEELVDHLKTFSISESPLEGTSHCHINLNETWTSKK 660
Query: 661 KLFQVEIQPEEKHEEFRKLFELISLLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNA 720
KLFQVEIQPEEKHEEFRKLFELISLLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNA
Sbjct: 661 KLFQVEIQPEEKHEEFRKLFELISLLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNA 720
Query: 721 FANEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSECVNLAKDNEVLHQELLS 780
FANEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSECVNLAKDNEVLHQELLS
Sbjct: 721 FANEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSECVNLAKDNEVLHQELLS 780
Query: 781 MRNVQEKCEKLEKDKKMLEEEVLNLKTHMEKDMVELGKLQEYKSELDERAVQEIEKLEEI 840
MRNVQEKCEKLEKDKKMLEEEVLNLKTHMEKDMVELGKLQEYKSELDERAVQEIEKLEEI
Sbjct: 781 MRNVQEKCEKLEKDKKMLEEEVLNLKTHMEKDMVELGKLQEYKSELDERAVQEIEKLEEI 840
Query: 841 HLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSKMKTAYEEVTTELEEFKEAFAG 900
HLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSKMKTAYEEVTTELEEFKEAFAG
Sbjct: 841 HLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSKMKTAYEEVTTELEEFKEAFAG 900
Query: 901 AVKANNSMSKKLMKSDKKIAVISTKLFMEKERMEYFLSTLPMRPDPELPCVENLNSIELN 960
AVKANNSMSKKLMKSDKKIAVISTKLFMEKERMEYFLSTLPMRPDPELPCVENLNSIELN
Sbjct: 901 AVKANNSMSKKLMKSDKKIAVISTKLFMEKERMEYFLSTLPMRPDPELPCVENLNSIELN 960
Query: 961 RKYIPKMAIRIPTSNPQTSNNCKNSLTELLLRWALAPIYFLL 1002
RKYIPKMAIRIPTSNPQTSNNCKNSLTELLLRWALAPIYFLL
Sbjct: 961 RKYIPKMAIRIPTSNPQTSNNCKNSLTELLLRWALAPIYFLL 1002
>gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1415
Score = 1942 bits (5032), Expect = 0.0
Identities = 991/1002 (98%), Positives = 996/1002 (99%)
Query: 1 MRKLFSFGRRLGQALLSSMDQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRD 60
MRKLFSFGRRLGQALLSSMDQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRD
Sbjct: 108 MRKLFSFGRRLGQALLSSMDQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRD 167
Query: 61 LDARDRKDRTVLHLACAHGRVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVL 120
LDARDRKDRTVLHLACAHGRVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVL
Sbjct: 168 LDARDRKDRTVLHLACAHGRVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVL 227
Query: 121 LECGANPNIEDIYGNTALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQ 180
LECGANPNIEDIYGNTALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQ
Sbjct: 228 LECGANPNIEDIYGNTALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQ 287
Query: 181 HMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYA 240
HMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYA
Sbjct: 288 HMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYA 347
Query: 241 LCSDLRSIRQQILEHKNKMLKNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQ 300
LCSDLRSIRQQILEHKNKMLKNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQ
Sbjct: 348 LCSDLRSIRQQILEHKNKMLKNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQ 407
Query: 301 ERLQRSENKQPQDSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYIQEIK 360
ERLQRSENKQPQDSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYIQEIK
Sbjct: 408 ERLQRSENKQPQDSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYIQEIK 467
Query: 361 SITEINANFEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVE 420
SITEINANFEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVE
Sbjct: 468 SITEINANFEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVE 527
Query: 421 SLHSSLATAINEYNEIVERKDLELVLWRADDVSRHEKMGSNISQLTDKNELLTEQVHKAR 480
SLHSSLATAINEYNEIVERKDLELVLWRADDVSRHEKMGSNISQLTDKNELLTEQVHKAR
Sbjct: 528 SLHSSLATAINEYNEIVERKDLELVLWRADDVSRHEKMGSNISQLTDKNELLTEQVHKAR 587
Query: 481 VKFNTLKGKLRETRDALREKTLALGSVQLDLRQAQHRIKEMKQMHPNGEAKESQSIGKQN 540
VKFNTLKGKLRETRDALREKTLALGSVQLDLRQAQHRIKEMKQMHPNGEAKESQSIGKQN
Sbjct: 588 VKFNTLKGKLRETRDALREKTLALGSVQLDLRQAQHRIKEMKQMHPNGEAKESQSIGKQN 647
Query: 541 SLEERIRQQELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKELMKEY 600
SLEERIRQQELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKELMKEY
Sbjct: 648 SLEERIRQQELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKELMKEY 707
Query: 601 NYLKEKLLQCEKEKAEREVIVREFQEELVDHLKTFSISESPLEGTSHCHINLNETWTSKK 660
NYLKEKLLQCEKEKAEREVIVREFQEELVDHLKTFSISESPLEGTSHCHINLNETWTSKK
Sbjct: 708 NYLKEKLLQCEKEKAEREVIVREFQEELVDHLKTFSISESPLEGTSHCHINLNETWTSKK 767
Query: 661 KLFQVEIQPEEKHEEFRKLFELISLLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNA 720
KLFQVEIQPEEKHEEFRKLFELISLLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNA
Sbjct: 768 KLFQVEIQPEEKHEEFRKLFELISLLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNA 827
Query: 721 FANEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSECVNLAKDNEVLHQELLS 780
FANEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSECVNLAKDNEVLHQELLS
Sbjct: 828 FANEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSECVNLAKDNEVLHQELLS 887
Query: 781 MRNVQEKCEKLEKDKKMLEEEVLNLKTHMEKDMVELGKLQEYKSELDERAVQEIEKLEEI 840
MRNVQEKCEKLEKDKKMLEEEVLNLKTHMEKDMVELGKLQEYKSELDERAVQEIEKLEEI
Sbjct: 888 MRNVQEKCEKLEKDKKMLEEEVLNLKTHMEKDMVELGKLQEYKSELDERAVQEIEKLEEI 947
Query: 841 HLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSKMKTAYEEVTTELEEFKEAFAG 900
HLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSKMKTAYEEVTTELEEFKEAFAG
Sbjct: 948 HLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSKMKTAYEEVTTELEEFKEAFAG 1007
Query: 901 AVKANNSMSKKLMKSDKKIAVISTKLFMEKERMEYFLSTLPMRPDPELPCVENLNSIELN 960
AVKANNSMSKKLMKSDKKIAVISTKLF EK+RM+YFLSTLP RP+PELPCVENLNSIELN
Sbjct: 1008 AVKANNSMSKKLMKSDKKIAVISTKLFTEKQRMKYFLSTLPTRPEPELPCVENLNSIELN 1067
Query: 961 RKYIPKMAIRIPTSNPQTSNNCKNSLTELLLRWALAPIYFLL 1002
RKYIPK AIRIPTSNPQTSNNCKN LTE+LL ALAP+YFLL
Sbjct: 1068 RKYIPKTAIRIPTSNPQTSNNCKNFLTEVLLCXALAPVYFLL 1109
>gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1415
Score = 1942 bits (5032), Expect = 0.0
Identities = 991/1002 (98%), Positives = 996/1002 (99%)
Query: 1 MRKLFSFGRRLGQALLSSMDQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRD 60
MRKLFSFGRRLGQALLSSMDQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRD
Sbjct: 108 MRKLFSFGRRLGQALLSSMDQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRD 167
Query: 61 LDARDRKDRTVLHLACAHGRVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVL 120
LDARDRKDRTVLHLACAHGRVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVL
Sbjct: 168 LDARDRKDRTVLHLACAHGRVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVL 227
Query: 121 LECGANPNIEDIYGNTALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQ 180
LECGANPNIEDIYGNTALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQ
Sbjct: 228 LECGANPNIEDIYGNTALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQ 287
Query: 181 HMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYA 240
HMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYA
Sbjct: 288 HMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYA 347
Query: 241 LCSDLRSIRQQILEHKNKMLKNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQ 300
LCSDLRSIRQQILEHKNKMLKNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQ
Sbjct: 348 LCSDLRSIRQQILEHKNKMLKNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQ 407
Query: 301 ERLQRSENKQPQDSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYIQEIK 360
ERLQRSENKQPQDSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYIQEIK
Sbjct: 408 ERLQRSENKQPQDSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYIQEIK 467
Query: 361 SITEINANFEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVE 420
SITEINANFEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVE
Sbjct: 468 SITEINANFEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVE 527
Query: 421 SLHSSLATAINEYNEIVERKDLELVLWRADDVSRHEKMGSNISQLTDKNELLTEQVHKAR 480
SLHSSLATAINEYNEIVERKDLELVLWRADDVSRHEKMGSNISQLTDKNELLTEQVHKAR
Sbjct: 528 SLHSSLATAINEYNEIVERKDLELVLWRADDVSRHEKMGSNISQLTDKNELLTEQVHKAR 587
Query: 481 VKFNTLKGKLRETRDALREKTLALGSVQLDLRQAQHRIKEMKQMHPNGEAKESQSIGKQN 540
VKFNTLKGKLRETRDALREKTLALGSVQLDLRQAQHRIKEMKQMHPNGEAKESQSIGKQN
Sbjct: 588 VKFNTLKGKLRETRDALREKTLALGSVQLDLRQAQHRIKEMKQMHPNGEAKESQSIGKQN 647
Query: 541 SLEERIRQQELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKELMKEY 600
SLEERIRQQELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKELMKEY
Sbjct: 648 SLEERIRQQELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKELMKEY 707
Query: 601 NYLKEKLLQCEKEKAEREVIVREFQEELVDHLKTFSISESPLEGTSHCHINLNETWTSKK 660
NYLKEKLLQCEKEKAEREVIVREFQEELVDHLKTFSISESPLEGTSHCHINLNETWTSKK
Sbjct: 708 NYLKEKLLQCEKEKAEREVIVREFQEELVDHLKTFSISESPLEGTSHCHINLNETWTSKK 767
Query: 661 KLFQVEIQPEEKHEEFRKLFELISLLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNA 720
KLFQVEIQPEEKHEEFRKLFELISLLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNA
Sbjct: 768 KLFQVEIQPEEKHEEFRKLFELISLLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNA 827
Query: 721 FANEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSECVNLAKDNEVLHQELLS 780
FANEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSECVNLAKDNEVLHQELLS
Sbjct: 828 FANEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSECVNLAKDNEVLHQELLS 887
Query: 781 MRNVQEKCEKLEKDKKMLEEEVLNLKTHMEKDMVELGKLQEYKSELDERAVQEIEKLEEI 840
MRNVQEKCEKLEKDKKMLEEEVLNLKTHMEKDMVELGKLQEYKSELDERAVQEIEKLEEI
Sbjct: 888 MRNVQEKCEKLEKDKKMLEEEVLNLKTHMEKDMVELGKLQEYKSELDERAVQEIEKLEEI 947
Query: 841 HLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSKMKTAYEEVTTELEEFKEAFAG 900
HLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSKMKTAYEEVTTELEEFKEAFAG
Sbjct: 948 HLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSKMKTAYEEVTTELEEFKEAFAG 1007
Query: 901 AVKANNSMSKKLMKSDKKIAVISTKLFMEKERMEYFLSTLPMRPDPELPCVENLNSIELN 960
AVKANNSMSKKLMKSDKKIAVISTKLF EK+RM+YFLSTLP RP+PELPCVENLNSIELN
Sbjct: 1008 AVKANNSMSKKLMKSDKKIAVISTKLFTEKQRMKYFLSTLPTRPEPELPCVENLNSIELN 1067
Query: 961 RKYIPKMAIRIPTSNPQTSNNCKNSLTELLLRWALAPIYFLL 1002
RKYIPK AIRIPTSNPQTSNNCKN LTE+LL ALAP+YFLL
Sbjct: 1068 RKYIPKTAIRIPTSNPQTSNNCKNFLTEVLLCXALAPVYFLL 1109
>gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1139
Score = 1850 bits (4791), Expect = 0.0
Identities = 944/1011 (93%), Positives = 977/1011 (96%), Gaps = 9/1011 (0%)
Query: 1 MRKLFSFGRRLGQALLSSMDQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRD 60
MRKL SFGRRLGQALLSSMDQEYAG GY IRDWELRKIHRAAIKGDAAEVE CLTRRFRD
Sbjct: 129 MRKLLSFGRRLGQALLSSMDQEYAGRGYHIRDWELRKIHRAAIKGDAAEVEHCLTRRFRD 188
Query: 61 LDARDRKDRTVLHLACAHGRVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVL 120
LD RDRKDRTVLHLACAHGRVQVVTLLL R+CQI+ICDRLNRTPLMKAVH QEEACAI+L
Sbjct: 189 LDVRDRKDRTVLHLACAHGRVQVVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAIIL 248
Query: 121 LECGANPNIEDIYGNTALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQ 180
L+ GANPNI+DIYGNTALHYAVYN+GTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQ
Sbjct: 249 LKRGANPNIKDIYGNTALHYAVYNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQ 308
Query: 181 HMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYA 240
HMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNI ISSQDMFGQTAEDYA
Sbjct: 309 HMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIHISSQDMFGQTAEDYA 368
Query: 241 LCSDLRSIRQQILEHKNKMLKNHLRNDNQETAAMKPANLKKRKER---------AKAEHN 291
C DLRSI+QQILEHKNKMLKNHLRNDNQETAAMKP NLKKRK+R AKAEHN
Sbjct: 369 FCCDLRSIQQQILEHKNKMLKNHLRNDNQETAAMKPENLKKRKKRKKLKKRKEGAKAEHN 428
Query: 292 LKVASEEKQERLQRSENKQPQDSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRK 351
LKVASEEKQERL+RSENKQPQDSQSYGKKKD M+GNFMLK+DIAMLKEELYAIKNDSLRK
Sbjct: 429 LKVASEEKQERLERSENKQPQDSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSLRK 488
Query: 352 EKKYIQEIKSITEINANFEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHN 411
EKKYIQEIKSITEINANFEKSVRLNE+MITK VA+YSQQLNDLKAENARLNS+LEKEKHN
Sbjct: 489 EKKYIQEIKSITEINANFEKSVRLNEEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHN 548
Query: 412 KERLEAEVESLHSSLATAINEYNEIVERKDLELVLWRADDVSRHEKMGSNISQLTDKNEL 471
KERLEAEVESLHS+LATAINEYNEI+ERKDLELVLWRADDVSRHE MGSNISQLTDKNEL
Sbjct: 549 KERLEAEVESLHSNLATAINEYNEILERKDLELVLWRADDVSRHETMGSNISQLTDKNEL 608
Query: 472 LTEQVHKARVKFNTLKGKLRETRDALREKTLALGSVQLDLRQAQHRIKEMKQMHPNGEAK 531
LTEQVHKARVKFNTLKGKLRETRDALREKTLAL SVQLDL+QAQHRIKEMKQMHPNGEAK
Sbjct: 609 LTEQVHKARVKFNTLKGKLRETRDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAK 668
Query: 532 ESQSIGKQNSLEERIRQQELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEE 591
ESQSIGKQNS EERIRQ+ELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEE
Sbjct: 669 ESQSIGKQNSSEERIRQRELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEE 728
Query: 592 RNKELMKEYNYLKEKLLQCEKEKAEREVIVREFQEELVDHLKTFSISESPLEGTSHCHIN 651
RNKELM EYNYLKEKLLQ EKEKAEREVIVREFQEELVDHLK FS+SESPLEGTSHCHIN
Sbjct: 729 RNKELMNEYNYLKEKLLQYEKEKAEREVIVREFQEELVDHLKKFSMSESPLEGTSHCHIN 788
Query: 652 LNETWTSKKKLFQVEIQPEEKHEEFRKLFELISLLNYTADQIRKKNRELEEEATGYKKCL 711
L+ETWTSKKKLFQVEIQPEEKHEEFRK+FELISLLNYTADQIRKKNRELEEEATGYKKCL
Sbjct: 789 LDETWTSKKKLFQVEIQPEEKHEEFRKVFELISLLNYTADQIRKKNRELEEEATGYKKCL 848
Query: 712 EMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSECVNLAKDN 771
EMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKF+DL+AEKEAVSS+CVNLAKDN
Sbjct: 849 EMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFDDLMAEKEAVSSKCVNLAKDN 908
Query: 772 EVLHQELLSMRNVQEKCEKLEKDKKMLEEEVLNLKTHMEKDMVELGKLQEYKSELDERAV 831
EVLHQELLSM VQEKCEKLEKDKKMLEE+VLNLKTHMEKDMVELGK+QEYKSELDERA+
Sbjct: 909 EVLHQELLSMGKVQEKCEKLEKDKKMLEEKVLNLKTHMEKDMVELGKVQEYKSELDERAM 968
Query: 832 QEIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSKMKTAYEEVTTEL 891
Q IEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSKMKTAYE+VTTEL
Sbjct: 969 QAIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSKMKTAYEDVTTEL 1028
Query: 892 EEFKEAFAGAVKANNSMSKKLMKSDKKIAVISTKLFMEKERMEYFLSTLPMRPDPELPCV 951
EE+KEAFA A+KAN+SMS+K+ KSDKKIAVISTKLFMEKERMEYFLSTLPMRPDPELPCV
Sbjct: 1029 EEYKEAFAVALKANSSMSEKITKSDKKIAVISTKLFMEKERMEYFLSTLPMRPDPELPCV 1088
Query: 952 ENLNSIELNRKYIPKMAIRIPTSNPQTSNNCKNSLTELLLRWALAPIYFLL 1002
ENLNSIELNRKYIPKMAIRIPTSNPQTSNNCKNSLTELLLRWALAPIYFLL
Sbjct: 1089 ENLNSIELNRKYIPKMAIRIPTSNPQTSNNCKNSLTELLLRWALAPIYFLL 1139
>gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1363
Score = 1848 bits (4788), Expect = 0.0
Identities = 943/1011 (93%), Positives = 977/1011 (96%), Gaps = 9/1011 (0%)
Query: 1 MRKLFSFGRRLGQALLSSMDQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRD 60
MRKL SFGRRLGQALLSSMDQEYAG GY IRDWELRKIHRAAIKGDAAEVE CLTRRFRD
Sbjct: 100 MRKLLSFGRRLGQALLSSMDQEYAGRGYHIRDWELRKIHRAAIKGDAAEVEHCLTRRFRD 159
Query: 61 LDARDRKDRTVLHLACAHGRVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVL 120
LD RD+KDRTVLHLACAHGRVQVVTLLL R+CQI+ICDRLNRTPLMKAVH QEEACAI+L
Sbjct: 160 LDVRDKKDRTVLHLACAHGRVQVVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAIIL 219
Query: 121 LECGANPNIEDIYGNTALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQ 180
L+ GANPNI+DIYGNTALHYAVYN+GTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQ
Sbjct: 220 LKRGANPNIKDIYGNTALHYAVYNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQ 279
Query: 181 HMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYA 240
HMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNI ISSQDMFGQTAEDYA
Sbjct: 280 HMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIHISSQDMFGQTAEDYA 339
Query: 241 LCSDLRSIRQQILEHKNKMLKNHLRNDNQETAAMKPANLKKRKER---------AKAEHN 291
C DLRSI+QQILEHKNKMLKNHLRNDNQETAAMKP NLKKRK+R AKAEHN
Sbjct: 340 FCCDLRSIQQQILEHKNKMLKNHLRNDNQETAAMKPENLKKRKKRKKLKKRKEGAKAEHN 399
Query: 292 LKVASEEKQERLQRSENKQPQDSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRK 351
LKVASEEKQERL+RSENKQPQDSQSYGKKKD M+GNFMLK+DIAMLKEELYAIKNDSLRK
Sbjct: 400 LKVASEEKQERLERSENKQPQDSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSLRK 459
Query: 352 EKKYIQEIKSITEINANFEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHN 411
EKKYIQEIKSITEINANFEKSVRLNE+MITK VA+YSQQLNDLKAENARLNS+LEKEKHN
Sbjct: 460 EKKYIQEIKSITEINANFEKSVRLNEEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHN 519
Query: 412 KERLEAEVESLHSSLATAINEYNEIVERKDLELVLWRADDVSRHEKMGSNISQLTDKNEL 471
KERLEAEVESLHS+LATAINEYNEI+ERKDLELVLWRADDVSRHE MGSNISQLTDKNEL
Sbjct: 520 KERLEAEVESLHSNLATAINEYNEILERKDLELVLWRADDVSRHETMGSNISQLTDKNEL 579
Query: 472 LTEQVHKARVKFNTLKGKLRETRDALREKTLALGSVQLDLRQAQHRIKEMKQMHPNGEAK 531
LTEQVHKARVKFNTLKGKLRETRDALREKTLAL SVQLDL+QAQHRIKEMKQMHPNGEAK
Sbjct: 580 LTEQVHKARVKFNTLKGKLRETRDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAK 639
Query: 532 ESQSIGKQNSLEERIRQQELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEE 591
ESQSIGKQNS EERIRQ+ELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEE
Sbjct: 640 ESQSIGKQNSSEERIRQRELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEE 699
Query: 592 RNKELMKEYNYLKEKLLQCEKEKAEREVIVREFQEELVDHLKTFSISESPLEGTSHCHIN 651
RNKELM EYNYLKEKLLQ EKEKAEREVIVREFQEELVDHLK FS+SESPLEGTSHCHIN
Sbjct: 700 RNKELMNEYNYLKEKLLQYEKEKAEREVIVREFQEELVDHLKKFSMSESPLEGTSHCHIN 759
Query: 652 LNETWTSKKKLFQVEIQPEEKHEEFRKLFELISLLNYTADQIRKKNRELEEEATGYKKCL 711
L+ETWTSKKKLFQVEIQPEEKHEEFRK+FELISLLNYTADQIRKKNRELEEEATGYKKCL
Sbjct: 760 LDETWTSKKKLFQVEIQPEEKHEEFRKVFELISLLNYTADQIRKKNRELEEEATGYKKCL 819
Query: 712 EMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSECVNLAKDN 771
EMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKF+DL+AEKEAVSS+CVNLAKDN
Sbjct: 820 EMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFDDLMAEKEAVSSKCVNLAKDN 879
Query: 772 EVLHQELLSMRNVQEKCEKLEKDKKMLEEEVLNLKTHMEKDMVELGKLQEYKSELDERAV 831
EVLHQELLSM VQEKCEKLEKDKKMLEE+VLNLKTHMEKDMVELGK+QEYKSELDERA+
Sbjct: 880 EVLHQELLSMGKVQEKCEKLEKDKKMLEEKVLNLKTHMEKDMVELGKVQEYKSELDERAM 939
Query: 832 QEIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSKMKTAYEEVTTEL 891
Q IEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSKMKTAYE+VTTEL
Sbjct: 940 QAIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSKMKTAYEDVTTEL 999
Query: 892 EEFKEAFAGAVKANNSMSKKLMKSDKKIAVISTKLFMEKERMEYFLSTLPMRPDPELPCV 951
EE+KEAFA A+KAN+SMS+K+ KSDKKIAVISTKLFMEKERMEYFLSTLPMRPDPELPCV
Sbjct: 1000 EEYKEAFAVALKANSSMSEKITKSDKKIAVISTKLFMEKERMEYFLSTLPMRPDPELPCV 1059
Query: 952 ENLNSIELNRKYIPKMAIRIPTSNPQTSNNCKNSLTELLLRWALAPIYFLL 1002
ENLNSIELNRKYIPKMAIRIPTSNPQTSNNCKNSLTELLLRWALAPIYFLL
Sbjct: 1060 ENLNSIELNRKYIPKMAIRIPTSNPQTSNNCKNSLTELLLRWALAPIYFLL 1110
>gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1366
Score = 1848 bits (4788), Expect = 0.0
Identities = 943/1011 (93%), Positives = 977/1011 (96%), Gaps = 9/1011 (0%)
Query: 1 MRKLFSFGRRLGQALLSSMDQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRD 60
MRKL SFGRRLGQALLSSMDQEYAG GY IRDWELRKIHRAAIKGDAAEVE CLTRRFRD
Sbjct: 129 MRKLLSFGRRLGQALLSSMDQEYAGRGYHIRDWELRKIHRAAIKGDAAEVEHCLTRRFRD 188
Query: 61 LDARDRKDRTVLHLACAHGRVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVL 120
LD RD+KDRTVLHLACAHGRVQVVTLLL R+CQI+ICDRLNRTPLMKAVH QEEACAI+L
Sbjct: 189 LDVRDKKDRTVLHLACAHGRVQVVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAIIL 248
Query: 121 LECGANPNIEDIYGNTALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQ 180
L+ GANPNI+DIYGNTALHYAVYN+GTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQ
Sbjct: 249 LKRGANPNIKDIYGNTALHYAVYNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQ 308
Query: 181 HMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYA 240
HMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNI ISSQDMFGQTAEDYA
Sbjct: 309 HMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIHISSQDMFGQTAEDYA 368
Query: 241 LCSDLRSIRQQILEHKNKMLKNHLRNDNQETAAMKPANLKKRKER---------AKAEHN 291
C DLRSI+QQILEHKNKMLKNHLRNDNQETAAMKP NLKKRK+R AKAEHN
Sbjct: 369 FCCDLRSIQQQILEHKNKMLKNHLRNDNQETAAMKPENLKKRKKRKKLKKRKEGAKAEHN 428
Query: 292 LKVASEEKQERLQRSENKQPQDSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRK 351
LKVASEEKQERL+RSENKQPQDSQSYGKKKD M+GNFMLK+DIAMLKEELYAIKNDSLRK
Sbjct: 429 LKVASEEKQERLERSENKQPQDSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSLRK 488
Query: 352 EKKYIQEIKSITEINANFEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHN 411
EKKYIQEIKSITEINANFEKSVRLNE+MITK VA+YSQQLNDLKAENARLNS+LEKEKHN
Sbjct: 489 EKKYIQEIKSITEINANFEKSVRLNEEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHN 548
Query: 412 KERLEAEVESLHSSLATAINEYNEIVERKDLELVLWRADDVSRHEKMGSNISQLTDKNEL 471
KERLEAEVESLHS+LATAINEYNEI+ERKDLELVLWRADDVSRHE MGSNISQLTDKNEL
Sbjct: 549 KERLEAEVESLHSNLATAINEYNEILERKDLELVLWRADDVSRHETMGSNISQLTDKNEL 608
Query: 472 LTEQVHKARVKFNTLKGKLRETRDALREKTLALGSVQLDLRQAQHRIKEMKQMHPNGEAK 531
LTEQVHKARVKFNTLKGKLRETRDALREKTLAL SVQLDL+QAQHRIKEMKQMHPNGEAK
Sbjct: 609 LTEQVHKARVKFNTLKGKLRETRDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAK 668
Query: 532 ESQSIGKQNSLEERIRQQELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEE 591
ESQSIGKQNS EERIRQ+ELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEE
Sbjct: 669 ESQSIGKQNSSEERIRQRELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEE 728
Query: 592 RNKELMKEYNYLKEKLLQCEKEKAEREVIVREFQEELVDHLKTFSISESPLEGTSHCHIN 651
RNKELM EYNYLKEKLLQ EKEKAEREVIVREFQEELVDHLK FS+SESPLEGTSHCHIN
Sbjct: 729 RNKELMNEYNYLKEKLLQYEKEKAEREVIVREFQEELVDHLKKFSMSESPLEGTSHCHIN 788
Query: 652 LNETWTSKKKLFQVEIQPEEKHEEFRKLFELISLLNYTADQIRKKNRELEEEATGYKKCL 711
L+ETWTSKKKLFQVEIQPEEKHEEFRK+FELISLLNYTADQIRKKNRELEEEATGYKKCL
Sbjct: 789 LDETWTSKKKLFQVEIQPEEKHEEFRKVFELISLLNYTADQIRKKNRELEEEATGYKKCL 848
Query: 712 EMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSECVNLAKDN 771
EMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKF+DL+AEKEAVSS+CVNLAKDN
Sbjct: 849 EMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFDDLMAEKEAVSSKCVNLAKDN 908
Query: 772 EVLHQELLSMRNVQEKCEKLEKDKKMLEEEVLNLKTHMEKDMVELGKLQEYKSELDERAV 831
EVLHQELLSM VQEKCEKLEKDKKMLEE+VLNLKTHMEKDMVELGK+QEYKSELDERA+
Sbjct: 909 EVLHQELLSMGKVQEKCEKLEKDKKMLEEKVLNLKTHMEKDMVELGKVQEYKSELDERAM 968
Query: 832 QEIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSKMKTAYEEVTTEL 891
Q IEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSKMKTAYE+VTTEL
Sbjct: 969 QAIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSKMKTAYEDVTTEL 1028
Query: 892 EEFKEAFAGAVKANNSMSKKLMKSDKKIAVISTKLFMEKERMEYFLSTLPMRPDPELPCV 951
EE+KEAFA A+KAN+SMS+K+ KSDKKIAVISTKLFMEKERMEYFLSTLPMRPDPELPCV
Sbjct: 1029 EEYKEAFAVALKANSSMSEKITKSDKKIAVISTKLFMEKERMEYFLSTLPMRPDPELPCV 1088
Query: 952 ENLNSIELNRKYIPKMAIRIPTSNPQTSNNCKNSLTELLLRWALAPIYFLL 1002
ENLNSIELNRKYIPKMAIRIPTSNPQTSNNCKNSLTELLLRWALAPIYFLL
Sbjct: 1089 ENLNSIELNRKYIPKMAIRIPTSNPQTSNNCKNSLTELLLRWALAPIYFLL 1139
>gi|154354990 ankyrin repeat domain 26 [Homo sapiens]
Length = 1710
Score = 521 bits (1341), Expect = e-147
Identities = 331/812 (40%), Positives = 490/812 (60%), Gaps = 87/812 (10%)
Query: 251 QILEHKNKMLKNHL------RNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQ 304
Q LE + + +K++L RND Q + + N + ++ H K E ++
Sbjct: 838 QTLEMELRTVKSNLNQVVQERNDAQRQLS-REQNARMLQDGILTNHLSKQKEIEMAQKKM 896
Query: 305 RSENKQPQDSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYIQEIKSITE 364
SEN S S+ ++KD + N ML+++IAML+ E+ IKN + KEKK +++K + E
Sbjct: 897 NSEN-----SHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKE 951
Query: 365 INANFEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVESLHS 424
N + +K+++ NE+ +T+T+++Y+ +L+ L AENA LNS+LE EK +KERLEAEVES HS
Sbjct: 952 KNEDLQKTIKQNEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESYHS 1011
Query: 425 SLATAINEYNEI-VERKDLELVLWRA-DDVSR-HEKMGSNISQLTDKNELLTEQVHKARV 481
LA AI++ ++ +++LEL RA D+ SR +KM ++S L D NE+L++Q+ K
Sbjct: 1012 RLAAAIHDRDQSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLFKTES 1071
Query: 482 KFNTLKGKLRETRDALREKTLALGSVQLDLRQAQHRIKEMKQMHPNGEAKESQSIGKQNS 541
K N+L+ + TRDALREKTL L VQ DL Q Q ++KEM+Q + N + K ++ IGKQ S
Sbjct: 1072 KLNSLEIEFHHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQES 1131
Query: 542 LEERIRQQELENLLLERQLEDARKEGDNKE-IVINIHRDC--------LENGKEDLL-EE 591
+EER+ Q + EN+LL +QL+DA + DNKE VINI E+ K+ LL EE
Sbjct: 1132 VEERLSQLQSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSLLLEE 1191
Query: 592 RNKELMKEYNYLKEKLLQCEKE-------------------------KAEREVIVR---E 623
RNKEL+ E N+LKE+ Q E E +A EV R
Sbjct: 1192 RNKELISECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRYRIN 1251
Query: 624 FQEELVDHLKTFSISESPLEGTSHCHI-------------------NLNETWTSKKKLFQ 664
++E D K + L+ H N T KK++ +
Sbjct: 1252 LEDETQDLKKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVTVKKQMDK 1311
Query: 665 VE-IQP--------EEKHEEFRKLFELISLLNYTADQIRKKNRELEEEATGYKKCLEMTI 715
+E +Q E++ E+ +KL EL L DQ KKN ELE E TG+K L+MT
Sbjct: 1312 IEELQKNLLNANLSEDEKEQLKKLMELKQSLECNLDQEMKKNVELEREITGFKNLLKMTR 1371
Query: 716 NMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSECVNLAKDNEVLH 775
LN + N +FS HGDL T Q +MDI KLK K +DL AE E S+C++L N++L
Sbjct: 1372 KKLNEYENGEFSFHGDLKTSQFEMDIQINKLKHKIDDLTAELETAGSKCLHLDTKNQILQ 1431
Query: 776 QELLSMRNVQEKCEKLEKDKKMLEEEVLNLKTHMEKDMVELGKLQEYKSELDERAVQEI- 834
+ELLSM+ VQ+KCEKL+K+KK LE+EV+NL++H+E++MVELG++++YK E++ERA QEI
Sbjct: 1432 EELLSMKTVQKKCEKLQKNKKKLEQEVINLRSHIERNMVELGQVKQYKQEIEERARQEIA 1491
Query: 835 EKLEEIH--LQKQAEYEKQLEQLNKDNTASLKKK-ELTLKDVECKFSKMKTAYEEVT-TE 890
EKL+E++ LQ QA ++ LEQ ++N AS+K + EL +KD+E + SK+KT+ E+ TE
Sbjct: 1492 EKLKEVNLFLQAQAASQENLEQFRENNFASMKSQMELRIKDLESELSKIKTSQEDFNKTE 1551
Query: 891 LEEFKEAFAGAVKANNSMSKKLMKSDKKIAVISTKLFMEKERMEYFLSTLPMRPDPELPC 950
LE++K+ + +K S+S KL K+++++A ++TKL +EK++ +TL RP E PC
Sbjct: 1552 LEKYKQLYLEELKVRKSLSSKLTKTNERLAEVNTKLLVEKQQSRSLFTTLTTRPVMEPPC 1611
Query: 951 VENL-NSIELNRKYIPKMAIRIPTSNPQTSNN 981
V NL NS++LNRK IP+ + I TSNP+ SNN
Sbjct: 1612 VGNLNNSLDLNRKLIPRENLVISTSNPRASNN 1643
Score = 207 bits (527), Expect = 4e-53
Identities = 99/185 (53%), Positives = 140/185 (75%)
Query: 23 YAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLDARDRKDRTVLHLACAHGRVQ 82
Y+ PGY +RD +L KIH+AA G+ A+V++ L R L+ RD+ +RT LHLACA+G +
Sbjct: 35 YSQPGYHVRDRDLGKIHKAASAGNVAKVQQILLLRKNGLNDRDKMNRTALHLACANGHPE 94
Query: 83 VVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLECGANPNIEDIYGNTALHYAV 142
VVTLL+ R+CQ+++CD NRT LMKAV QEE CA +LLE GA+PN+ D++GNTALHYAV
Sbjct: 95 VVTLLVDRKCQLNVCDNENRTALMKAVQCQEEKCATILLEHGADPNLADVHGNTALHYAV 154
Query: 143 YNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNFKRT 202
YN+ S+A +LL + ANIEA NK+ TPLL A++ ++Q MVEFL+K +AN++AVD + +
Sbjct: 155 YNEDISVATKLLLYDANIEAKNKDDLTPLLLAVSGKKQQMVEFLIKKKANVNAVDKLESS 214
Query: 203 ALILA 207
+++
Sbjct: 215 HQLIS 219
Score = 70.1 bits (170), Expect = 1e-11
Identities = 150/743 (20%), Positives = 305/743 (41%), Gaps = 94/743 (12%)
Query: 231 MFGQTAEDYALCSDLRSIRQQILEHKNKMLKNHLRN--DNQETAAMKPANLKKRKERAKA 288
M G A D R++ + ++ HL+ + +++ K +K + A
Sbjct: 463 MSGSRNFKMAKLEDTRNVGMPVAHMESPERYLHLKPTIEMKDSVPNKAGGMKDVQTSKAA 522
Query: 289 EHNLKVASEEKQERLQRSENKQPQDSQSYGKKK-----------DAMYGNFMLKKDIAML 337
EH+L+VASEE+QER + SEN QPQ + K + D + D L
Sbjct: 523 EHDLEVASEEEQER-EGSENNQPQVEEERKKHRNNEMEVSANIHDGATDDAEDDDDDDGL 581
Query: 338 KEELYAIKNDSL---RKEKK---------YIQEIKSITEINANFEKSVRL----NEKMIT 381
++ + + D RKE K ++E+KS + ++SV ++T
Sbjct: 582 IQKRKSGETDHQQFPRKENKEYASSGPALQMKEVKSTEKEKRTSKESVNSPVFGKASLLT 641
Query: 382 KTVARYSQQ--LNDLKAENARLNSELEKEKHN-KERLEA--EVESLHSSLATAINE---- 432
+ + L+++ + R + EK+ K ++++ +V+ L S TA +
Sbjct: 642 GGLLQVDDDSSLSEIDEDEGRPTKKTSNEKNKVKNQIQSMDDVDDLTQSSETASEDCELP 701
Query: 433 ------YNEIVERKDLELVLWRADDVSRHEKMGSNIS--QLTD--KN--ELLTEQVHKAR 480
+ ++E+ +E D VS + + +S +L + KN ELLT ++ K
Sbjct: 702 HSSYKNFMLLIEQLGMEC----KDSVSLLKIQDAALSCERLLELKKNHCELLTVKIKKME 757
Query: 481 VKFNTLKGKLRETRDALREKTLALGSVQLDLRQAQHRIKEMKQMHPNGEAKESQSIGKQN 540
K N L+ +L ET++ + + +L + + + ++ N + + +
Sbjct: 758 DKVNVLQRELSETKEIKSQLEHQKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLR 817
Query: 541 SLEERIRQQELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKELMKE- 599
EE+ R++ LE L+ E + +N + + L E+N ++++
Sbjct: 818 RKEEQYRKEVEVKQQLELSLQTLEMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDG 877
Query: 600 --YNYL-KEKLLQCEKEKAEREVIVREFQEELVDHLKTFSISESPLEGTSHCHINLNETW 656
N+L K+K ++ ++K E +E+ + H K + E N+
Sbjct: 878 ILTNHLSKQKEIEMAQKKMNSENSHSHEEEKDLSH-KNSMLQEEIAMLRLEIDTIKNQNQ 936
Query: 657 TSKKKLFQVEIQPEEKHEEFRK--------LFELISLLNYTADQIRKKNRELE---EEAT 705
+KK F+ +EK+E+ +K L + IS N + +N L E
Sbjct: 937 EKEKKCFEDLKIVKEKNEDLQKTIKQNEETLTQTISQYNGRLSVLTAENAMLNSKLENEK 996
Query: 706 GYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSECV 765
K+ LE + ++ T + ++++ F++ + + + L ++ ++ +
Sbjct: 997 QSKERLEAEVESYHSRLAAAIHDRDQSETSKRELELAFQRARDECSRL---QDKMNFDVS 1053
Query: 766 NLAKDNEVLHQELLSMRNVQEKCE-KLEKDKKMLEEEVLNLKTHMEKDMVELGKLQEYKS 824
NL +NE+L Q+L + E + + L E+ L L E+ +L + Q
Sbjct: 1054 NLKDNNEILSQQLFKTESKLNSLEIEFHHTRDALREKTLGL----ERVQKDLSQTQCQMK 1109
Query: 825 ELDERAVQEIEKLEEIHLQKQAEYEKQLEQLNKDNTA----------SLKKKELTLKDVE 874
E++++ E K+ + ++ KQ E++L QL +N KE T+ +++
Sbjct: 1110 EMEQKYQNEQVKVNK-YIGKQESVEERLSQLQSENMLLRQQLDDAHNKADNKEKTVINIQ 1168
Query: 875 CKF----SKMKTAYEEVTTELEE 893
+F K++ E+ + LEE
Sbjct: 1169 DQFHAIVQKLQAESEKQSLLLEE 1191
Score = 46.2 bits (108), Expect = 2e-04
Identities = 113/576 (19%), Positives = 226/576 (39%), Gaps = 75/576 (13%)
Query: 139 HYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFL--LKNQANIHAV 196
H NK ++ HA ++ L E L + R + ++ LK + +
Sbjct: 1154 HNKADNKEKTVINIQDQFHAIVQKLQAESEKQSLL-LEERNKELISECNHLKERQYQYEN 1212
Query: 197 DNFKRTALILAVQHNLSSIVTL--LLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQILE 254
+ +R ++ +Q L+ + + + ++ ++S+ E L L IR Q+ E
Sbjct: 1213 EKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRYRINLEDETQDLKKKLGQIRNQLQE 1272
Query: 255 HKNKML------------KNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQER 302
+++ K L DN + + K +E K N ++ +EK++
Sbjct: 1273 AQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVTVKKQMDKIEELQKNLLNANLSEDEKEQL 1332
Query: 303 LQRSENKQPQDSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIK---NDSLRKEKKYIQEI 359
+ E KQ + + K N L+++I K L + N+ E + ++
Sbjct: 1333 KKLMELKQSLECNLDQEMKK----NVELEREITGFKNLLKMTRKKLNEYENGEFSFHGDL 1388
Query: 360 KSITEINANFEKSVRLNEKM-----ITKTVARYSQQLNDLKAENARLNSEL--------- 405
K+ + FE +++N+ +T + + L +N L EL
Sbjct: 1389 KT-----SQFEMDIQINKLKHKIDDLTAELETAGSKCLHLDTKNQILQEELLSMKTVQKK 1443
Query: 406 -EKEKHNKERLEAEVESLHSSLAT------AINEYNEIVERKDLELVLWRADDVS----R 454
EK + NK++LE EV +L S + + +Y + +E + + + + +V+
Sbjct: 1444 CEKLQKNKKKLEQEVINLRSHIERNMVELGQVKQYKQEIEERARQEIAEKLKEVNLFLQA 1503
Query: 455 HEKMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALRE--KTLALGSVQLDLR 512
N+ Q + N + + R+K L+ +L + + + + KT QL L
Sbjct: 1504 QAASQENLEQFRENNFASMKSQMELRIK--DLESELSKIKTSQEDFNKTELEKYKQLYLE 1561
Query: 513 QAQHRIKEMKQMHPNGEAKESQSIGKQNS--LEERIRQQELENLLLERQLEDARKEGD-N 569
+ + R ++ K ++ + + N+ L E+ + + L L R + + G+ N
Sbjct: 1562 ELKVRKSLSSKL-----TKTNERLAEVNTKLLVEKQQSRSLFTTLTTRPVMEPPCVGNLN 1616
Query: 570 KEIVINIHRDCLENGKEDLLEERNKELMKEYNYLKEKLLQCEKEKAEREVIVREFQEELV 629
+ +N EN R E NYL + + EK I RE +E
Sbjct: 1617 NSLDLNRKLIPRENLVISTSNPRASNNSME-NYLSKMQQELEKN------ITRELKEAAA 1669
Query: 630 DHLKTFSISESPLEGTSHCHINLNETWTSKKKLFQV 665
+ L++ SI+ SPL T ++N + W + ++ QV
Sbjct: 1670 E-LESGSIA-SPLGSTDESNLNQDLVWKASREYVQV 1703
Score = 34.3 bits (77), Expect = 0.60
Identities = 37/179 (20%), Positives = 75/179 (41%), Gaps = 15/179 (8%)
Query: 751 NDLVAEKEAVSSECV--NLAKDNEVLHQELLSMRNVQEKCEKLEKDKKMLEEEVLNLK-T 807
+DL E S +C + + N +L E L M +D + E +L LK
Sbjct: 685 DDLTQSSETASEDCELPHSSYKNFMLLIEQLGMECKDSVSLLKIQDAALSCERLLELKKN 744
Query: 808 HMEKDMVELGKLQEYKSELDERAVQEIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKE 867
H E V++ K+++ K + +R + E ++++ ++ E+E++L L
Sbjct: 745 HCELLTVKIKKMED-KVNVLQRELSETKEIKSQLEHQKVEWERELCSLR----------- 792
Query: 868 LTLKDVECKFSKMKTAYEEVTTELEEFKEAFAGAVKANNSMSKKLMKSDKKIAVISTKL 926
+L E K T YE++ +L +E + V+ + L + ++ + + L
Sbjct: 793 FSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQTLEMELRTVKSNL 851
>gi|60460920 ankyrin repeat domain 20 family, member A3 [Homo
sapiens]
Length = 823
Score = 369 bits (948), Expect = e-102
Identities = 289/910 (31%), Positives = 439/910 (48%), Gaps = 132/910 (14%)
Query: 3 KLFSFGRRLGQALLSSMDQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLD 62
KLF FG R GQ S+D Y G GY IRD EL+KIHRAA+KGDAAEVERCL RR DLD
Sbjct: 2 KLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDLD 61
Query: 63 ARDRKDRTVLHLACAHGRVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLE 122
A D++ RT LHLACA G VQVVTLL++R+CQID+CD+ NRTPL++AVH QEEACA++LLE
Sbjct: 62 ALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLE 121
Query: 123 CGANPNIEDIYGNTALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHM 182
GANPN++DIYGNTALHYAVY++ TSLAE+LLSH A+IEAL+K+ NTPLLFAI +++ M
Sbjct: 122 HGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKM 181
Query: 183 VEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALC 242
VEFLLK +A+ HAVD +R+AL+LAV ++ IV +LL+QNI + +QDM G+ AEDYA+
Sbjct: 182 VEFLLKRKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAIS 241
Query: 243 SDLRSIRQQILEHKNKMLK-----------------NHLRNDNQETAAMKPANL-KKRKE 284
L I+QQILEHK K+LK + LR D+ + K N+ K+
Sbjct: 242 HHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQCV 301
Query: 285 RAKAEHNLKVASEEKQERLQRSENKQPQDSQSYGKK----KDAMYGNFMLKKDIAMLKEE 340
K L +S EK R+ + + P K +D + +K++ L+ E
Sbjct: 302 PEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAE 361
Query: 341 LYAIKNDSLRKEKKYIQEIKSITEI----NANFEKSVRLNEKMITKT----VARYSQQLN 392
A+ S +++++ + K ++ N N + ++L+E + T R +QQ
Sbjct: 362 -QALPVASEEEQERHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRK 420
Query: 393 DLKAENARLNSELEKEKHNKERLEAEVESLHSSLATAINEYNEIVERKDLELVLWRADDV 452
K + +L KE+H++ L+ E E +++ + E +ERK+
Sbjct: 421 IGKTYPQQFPKKL-KEEHDRCTLKQENEE-KTNVNMLYKKNREELERKE----------- 467
Query: 453 SRHEKMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKTLALGSVQLDLR 512
+ K QL + L + AR N E + + E + ++ D+
Sbjct: 468 -KQYKKEVEAKQLEPTVQSLEMKSKTARNTPNRDFHNHEEMKGLMDENCI----LKADIA 522
Query: 513 QAQHRIKEMKQMHPNGEAKESQSIGKQNSLEERIRQQELENLLLERQLEDARKEGDNKEI 572
+ I MK + ++ K+N + I+ + N LE K I
Sbjct: 523 ILRQEICTMK----------NDNLEKENKYLKDIKIVKETNAALE------------KYI 560
Query: 573 VINIHRDCLENGKEDLLEERNKELMKEYNYLK-------EKLLQCEKEKAEREVIVREFQ 625
+N E+++ E +E NYLK +LL+ ++ K E + +Q
Sbjct: 561 KLN----------EEMITETAFRYQQELNYLKAENTRLNAELLKEKESKKRLEADIESYQ 610
Query: 626 EELV-------DHLKTFSISESPLEGTSHCHINLNETWTSKKKLFQVEIQPEEKHEEFRK 678
L + +KT + LE T + + + K + E E+ E K
Sbjct: 611 SRLAAAISKHSESVKTERNLKLALERTRDVSVQVEMSSAISKVKDENEFLTEQLSETQIK 670
Query: 679 LFELISLLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLK 738
L T D +RKK+ LE + + T M + N +
Sbjct: 671 FNALKDKFRKTRDSLRKKSLALETVQNDLSQTQQQTQEMKEMYQNAE------------- 717
Query: 739 MDILFKKLKQKFNDLVAEKEAVSSECVNLAKDNEVLHQELLSMRNVQEKCEKLEKDKKML 798
K N+ + V +L ++N L Q+L D
Sbjct: 718 ---------AKVNNSTGKWNCVEERICHLQRENAWLVQQL---------------DDVHQ 753
Query: 799 EEEVLNLKTHMEKDMVELGKLQEYKSELDERAVQEIEKLEEIHLQKQAEYEKQLEQLNKD 858
+E+ + T++++ +E GK E ++ + E + L+E Q + E + + + +D
Sbjct: 754 KEDHKEIVTNIQRGFIESGKKDLVLEEKSKKLMNECDHLKESLFQYEREKTEGVVSIKED 813
Query: 859 NTASLKKKEL 868
+K +
Sbjct: 814 KYFQTSRKTI 823
>gi|60115723 ankyrin repeat domain 20 family, member A2 [Homo
sapiens]
Length = 823
Score = 369 bits (947), Expect = e-102
Identities = 290/904 (32%), Positives = 437/904 (48%), Gaps = 120/904 (13%)
Query: 3 KLFSFGRRLGQALLSSMDQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLD 62
KLF FG R GQ S+D Y G GY IRD EL+KIHRAA+KGDAAEVERCL RR DLD
Sbjct: 2 KLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDLD 61
Query: 63 ARDRKDRTVLHLACAHGRVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLE 122
A D++ RT LHLACA G VQVVTLL++R+CQID+CD+ NRTPL++AVH QEEACA++LLE
Sbjct: 62 ALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLE 121
Query: 123 CGANPNIEDIYGNTALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHM 182
GANPN++DIYGNTALHYAVY++ TSLAE+LLSH A+IEAL+K+ NTPLLFAI +++ M
Sbjct: 122 HGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKM 181
Query: 183 VEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALC 242
VEFLLK +A+ HAVD +R+AL+LAV ++ IV +LL+QNI + +QDM G+ AEDYA+
Sbjct: 182 VEFLLKRKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAIS 241
Query: 243 SDLRSIRQQILEHKNKMLK-----------------NHLRNDNQETAAMKPANL-KKRKE 284
L I+QQILEHK K+LK + LR D+ + K N+ K+
Sbjct: 242 HHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQCV 301
Query: 285 RAKAEHNLKVASEEKQERLQRSENKQPQDSQSYGKK----KDAMYGNFMLKKDIAMLKEE 340
K L +S EK R+ + + P K +D + +K++ L+ E
Sbjct: 302 PEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAE 361
Query: 341 LYAIKNDSLRKEKKYIQEIKSITEI----NANFEKSVRLNEKMITKT----VARYSQQLN 392
A+ S +++++ + K ++ N N + ++L+E + T R +QQ
Sbjct: 362 -QALPVASEEEQERHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRK 420
Query: 393 DLKAENARLNSELEKEKHNKERLEAEVESLHSSLATAINEYNEIVERKDLELVLWRADDV 452
K + +L KE+H++ L+ E E
Sbjct: 421 IGKTYPQQFPKKL-KEEHDRCTLKQENE-------------------------------- 447
Query: 453 SRHEKMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKTLALGSVQLDLR 512
EK +N++ L KN E+ K K K +L T +L K+ +
Sbjct: 448 ---EK--TNVNMLYKKNREELERKEKQYKKEVEAK-QLEPTVQSLEMKSKTARNTP---N 498
Query: 513 QAQHRIKEMK-QMHPNGEAKESQSIGKQNSLEERIRQQELENLLLERQLEDARKEGDNKE 571
+ H +EMK M N K +I +Q + E EN L + ++ ++ E
Sbjct: 499 RDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKYL-KDIKIVKETNAALE 557
Query: 572 IVINIHRDCLENGKEDLLEERNKELMKEYNYLKEKLLQCEKEKAEREVIVREFQEELV-- 629
I ++ + + +E N +L E L +LL+ ++ K E + +Q L
Sbjct: 558 KYIKLNEEMITETAFRYQQELN-DLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAA 616
Query: 630 -----DHLKTFSISESPLEGTSHCHINLNETWTSKKKLFQVEIQPEEKHEEFRKLFELIS 684
+ +KT + LE T + + + K + E E+ E K L
Sbjct: 617 ISKHSESVKTERNLKLALERTRDVSVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKD 676
Query: 685 LLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFK 744
T D +RKK+ LE + + T M + N +
Sbjct: 677 KFRKTRDSLRKKSLALETVQNDLSQTQQQTQEMKEMYQNAE------------------- 717
Query: 745 KLKQKFNDLVAEKEAVSSECVNLAKDNEVLHQELLSMRNVQEKCEKLEKDKKMLEEEVLN 804
K N+ + V +L ++N L Q+L D +E+
Sbjct: 718 ---AKVNNSTGKWNCVEERICHLQRENAWLVQQL---------------DDVHQKEDHKE 759
Query: 805 LKTHMEKDMVELGKLQEYKSELDERAVQEIEKLEEIHLQKQAEYEKQLEQLNKDNTASLK 864
+ T++++ +E GK E ++ + E + L+E Q + E + + + +D
Sbjct: 760 IVTNIQRGFIESGKKDLVLEEKSKKLMNECDHLKESLFQYEREKTEGVVSIKEDKYFQTS 819
Query: 865 KKEL 868
+K++
Sbjct: 820 RKKI 823
Score = 32.3 bits (72), Expect = 2.3
Identities = 43/203 (21%), Positives = 85/203 (41%), Gaps = 44/203 (21%)
Query: 744 KKLKQKFNDLVAEKEAVSSECVNLA--KDNEVLHQELLSMRNVQEKCEKLEKDKKMLEEE 801
KKLK++ + ++E VN+ K+ E L ++ EK K E + K LE
Sbjct: 431 KKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERK--------EKQYKKEVEAKQLEPT 482
Query: 802 VLNL----KTHMEKDMVELGKLQEYKSELDERAV---------QEIEKLEEIHLQKQAEY 848
V +L KT + +E K +DE + QEI ++ +L+K+ +Y
Sbjct: 483 VQSLEMKSKTARNTPNRDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKY 542
Query: 849 EKQLEQLNKDNTASLKKKELT--------------LKDVECKFSKM-------KTAYEEV 887
K ++ + + N A K +L L D++ + +++ K + + +
Sbjct: 543 LKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELNDLKAENTRLNAELLKEKESKKRL 602
Query: 888 TTELEEFKEAFAGAVKANNSMSK 910
++E ++ A A+ ++ K
Sbjct: 603 EADIESYQSRLAAAISKHSESVK 625
>gi|149363679 ankyrin repeat domain 20 family, member A4 [Homo
sapiens]
Length = 823
Score = 368 bits (945), Expect = e-101
Identities = 291/904 (32%), Positives = 435/904 (48%), Gaps = 120/904 (13%)
Query: 3 KLFSFGRRLGQALLSSMDQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLD 62
KLF FG R GQ S+D Y G GY IRD EL+KIHRAA+KGDAAEVERCL RR +LD
Sbjct: 2 KLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGELD 61
Query: 63 ARDRKDRTVLHLACAHGRVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLE 122
A D++ RT LHLACA G VQVVTLL++R+CQID+CD+ NRTPL++AVH QEEACA++LLE
Sbjct: 62 ALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLE 121
Query: 123 CGANPNIEDIYGNTALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHM 182
GANPN++DIYGNTALHYAVY++ TSLAE+LLSH A+IEAL+K+ NTPLLFAI +++ M
Sbjct: 122 HGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKM 181
Query: 183 VEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALC 242
VEFLLK +A+ HAVD +R+AL+LAV ++ IV +LL+QNI + +QDM G+ AEDYA+
Sbjct: 182 VEFLLKKKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAIS 241
Query: 243 SDLRSIRQQILEHKNKMLK-----------------NHLRNDNQETAAMKPANL-KKRKE 284
L I+QQILEHK K+LK + LR D+ + K N+ K+
Sbjct: 242 HHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQCV 301
Query: 285 RAKAEHNLKVASEEKQERLQRSENKQPQDSQSYGKK----KDAMYGNFMLKKDIAMLKEE 340
K L +S EK R+ + + P K +D + +K++ L+ E
Sbjct: 302 PEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAE 361
Query: 341 L---YAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEKMITKT----VARYSQQLND 393
A + + R E+ ++ + N N + ++L+E + T R +QQ
Sbjct: 362 QALPVASEEEQQRHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRKI 421
Query: 394 LKAENARLNSELEKEKHNKERLEAEVESLHSSLATAINEYNEIVERKDLELVLWRADDVS 453
K + +L KE+H++ L+ E E
Sbjct: 422 GKTYPQQFPKKL-KEEHDRCTLKQENE--------------------------------- 447
Query: 454 RHEKMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKT-LALGSVQLDLR 512
EK +N++ L KN E+ K K K +L T +L K+ A + D
Sbjct: 448 --EK--TNVNMLYKKNREELERKEKQYKKEVEAK-QLEPTVQSLEMKSKTARNTPNWDF- 501
Query: 513 QAQHRIKEMK-QMHPNGEAKESQSIGKQNSLEERIRQQELENLLLERQLEDARKEGDNKE 571
H +EMK M N K +I +Q + E EN L + ++ ++ E
Sbjct: 502 ---HNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKYL-KDIKIVKETNAALE 557
Query: 572 IVINIHRDCLENGKEDLLEERNKELMKEYNYLKEKLLQCEKEKAEREVIVREFQEELV-- 629
I ++ + + +E N +L E L +LL+ ++ K E + +Q L
Sbjct: 558 KYIKLNEEMITETAFRYQQELN-DLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAA 616
Query: 630 -----DHLKTFSISESPLEGTSHCHINLNETWTSKKKLFQVEIQPEEKHEEFRKLFELIS 684
+ +KT + LE T + + + K + E E+ E K L
Sbjct: 617 ISKHSESVKTERNLKLALERTQDVSVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKD 676
Query: 685 LLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFK 744
T D +RKK+ LE + + T M + N +
Sbjct: 677 KFRKTRDSLRKKSLALETVQNNLSQTQQQTQEMKEMYQNAE------------------- 717
Query: 745 KLKQKFNDLVAEKEAVSSECVNLAKDNEVLHQELLSMRNVQEKCEKLEKDKKMLEEEVLN 804
K N+ + V +L ++N L Q+L D +E+
Sbjct: 718 ---AKVNNSTGKWNCVEERICHLQRENAWLVQQL---------------DDVHQKEDHKE 759
Query: 805 LKTHMEKDMVELGKLQEYKSELDERAVQEIEKLEEIHLQKQAEYEKQLEQLNKDNTASLK 864
+ T++++ +E GK E ++ + E + L+E Q + E + + + +D
Sbjct: 760 IVTNIQRGFIESGKKDFVLEEKSKKLMNECDHLKESLFQYEREKTEVVVSIKEDKYFQTS 819
Query: 865 KKEL 868
+K++
Sbjct: 820 RKKI 823
Score = 32.3 bits (72), Expect = 2.3
Identities = 43/203 (21%), Positives = 85/203 (41%), Gaps = 44/203 (21%)
Query: 744 KKLKQKFNDLVAEKEAVSSECVNLA--KDNEVLHQELLSMRNVQEKCEKLEKDKKMLEEE 801
KKLK++ + ++E VN+ K+ E L ++ EK K E + K LE
Sbjct: 431 KKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERK--------EKQYKKEVEAKQLEPT 482
Query: 802 VLNL----KTHMEKDMVELGKLQEYKSELDERAV---------QEIEKLEEIHLQKQAEY 848
V +L KT + +E K +DE + QEI ++ +L+K+ +Y
Sbjct: 483 VQSLEMKSKTARNTPNWDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKY 542
Query: 849 EKQLEQLNKDNTASLKKKELT--------------LKDVECKFSKM-------KTAYEEV 887
K ++ + + N A K +L L D++ + +++ K + + +
Sbjct: 543 LKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELNDLKAENTRLNAELLKEKESKKRL 602
Query: 888 TTELEEFKEAFAGAVKANNSMSK 910
++E ++ A A+ ++ K
Sbjct: 603 EADIESYQSRLAAAISKHSESVK 625
>gi|156104901 ankyrin repeat domain 20 family, member A1 [Homo
sapiens]
Length = 823
Score = 367 bits (942), Expect = e-101
Identities = 291/905 (32%), Positives = 436/905 (48%), Gaps = 122/905 (13%)
Query: 3 KLFSFGRRLGQALLSSMDQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLD 62
KLF FG R GQ S+D Y G GY IRD EL+KIHRAA+KGDAAEVERCL RR DLD
Sbjct: 2 KLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDLD 61
Query: 63 ARDRKDRTVLHLACAHGRVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLE 122
A D++ RT LHLAC G VQVVTLL++R+CQID+CD+ NRTPL++AVH QEEACA++LLE
Sbjct: 62 ALDKQHRTALHLACTSGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLE 121
Query: 123 CGANPNIEDIYGNTALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHM 182
GANPN++DIYGNTALHYAVY++ TSLAE+LLSH A+IEAL+K+ NTPLLFAI +++ M
Sbjct: 122 HGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKM 181
Query: 183 VEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALC 242
VEFLLK +A+ HAVD +R+AL+LAV ++ IV +LL+QNI + +QDM G+ AEDYA+
Sbjct: 182 VEFLLKKKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAIS 241
Query: 243 SDLRSIRQQILEHKNKMLK-----------------NHLRNDNQETAAMKPANL-KKRKE 284
L I+QQILEHK K+LK + LR D+ + K N+ K+
Sbjct: 242 HHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQCV 301
Query: 285 RAKAEHNLKVASEEKQERLQRSENKQPQDSQSYGKK----KDAMYGNFMLKKDIAMLKEE 340
K L +S EK R+ + + P K +D + +K++ L+ E
Sbjct: 302 PEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAE 361
Query: 341 LYAIKNDSLRKEKKYIQEIKSITEI----NANFEKSVRLNEKMITKT----VARYSQQLN 392
A+ S +++++ + K ++ N N + ++L+E + T R +QQ
Sbjct: 362 -QALPVASEEEQERHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRK 420
Query: 393 DLKAENARLNSELEKEKHNKERLEAEVESLHSSLATAINEYNEIVERKDLELVLWRADDV 452
K + +L KE+H++ L+ E E
Sbjct: 421 IGKTYPQQFPKKL-KEEHDRCTLKQENE-------------------------------- 447
Query: 453 SRHEKMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKT-LALGSVQLDL 511
EK +N++ L KN E+ K K K +L T +L K+ A + D
Sbjct: 448 ---EK--TNVNMLYKKNREELERKEKQYKKEVEAK-QLEPTVQSLEMKSKTARNTPNWDF 501
Query: 512 RQAQHRIKEMK-QMHPNGEAKESQSIGKQNSLEERIRQQELENLLLERQLEDARKEGDNK 570
H +EMK M N K +I +Q + E EN L + ++ ++
Sbjct: 502 ----HNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKYL-KDIKIVKETNAAL 556
Query: 571 EIVINIHRDCLENGKEDLLEERNKELMKEYNYLKEKLLQCEKEKAEREVIVREFQEELV- 629
E I ++ + + +E N +L E L +LL+ ++ K E + +Q L
Sbjct: 557 EKYIKLNEEMITETAFRYQQELN-DLKAENTRLNAELLKEKESKKRLEADIESYQSRLAA 615
Query: 630 ------DHLKTFSISESPLEGTSHCHINLNETWTSKKKLFQVEIQPEEKHEEFRKLFELI 683
+ +KT + LE T + + + K + E E+ E K L
Sbjct: 616 AISKHSESVKTERNLKLALERTRDVSVQVEMSSAISKVKAENEFLTEQLSETQIKFNALK 675
Query: 684 SLLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILF 743
T D +RKK+ LE + + T M + N +
Sbjct: 676 DKFRKTRDSLRKKSLALETVQNDLSQTQQQTQEMKEMYQNAE------------------ 717
Query: 744 KKLKQKFNDLVAEKEAVSSECVNLAKDNEVLHQELLSMRNVQEKCEKLEKDKKMLEEEVL 803
K N+ + V +L ++N L Q+L D +E+
Sbjct: 718 ----AKVNNSTGKWNCVEERICHLQRENAWLVQQL---------------DDVHQKEDHK 758
Query: 804 NLKTHMEKDMVELGKLQEYKSELDERAVQEIEKLEEIHLQKQAEYEKQLEQLNKDNTASL 863
+ T++++ +E GK E ++ + E + L+E Q + E + + + +D
Sbjct: 759 EIVTNIQRGFIESGKKDLVLEEKSKKLMNECDHLKESLFQYEREKTEGVVSIKEDKYFQT 818
Query: 864 KKKEL 868
+K +
Sbjct: 819 SRKTI 823
Score = 32.3 bits (72), Expect = 2.3
Identities = 43/203 (21%), Positives = 85/203 (41%), Gaps = 44/203 (21%)
Query: 744 KKLKQKFNDLVAEKEAVSSECVNLA--KDNEVLHQELLSMRNVQEKCEKLEKDKKMLEEE 801
KKLK++ + ++E VN+ K+ E L ++ EK K E + K LE
Sbjct: 431 KKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERK--------EKQYKKEVEAKQLEPT 482
Query: 802 VLNL----KTHMEKDMVELGKLQEYKSELDERAV---------QEIEKLEEIHLQKQAEY 848
V +L KT + +E K +DE + QEI ++ +L+K+ +Y
Sbjct: 483 VQSLEMKSKTARNTPNWDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKY 542
Query: 849 EKQLEQLNKDNTASLKKKELT--------------LKDVECKFSKM-------KTAYEEV 887
K ++ + + N A K +L L D++ + +++ K + + +
Sbjct: 543 LKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELNDLKAENTRLNAELLKEKESKKRL 602
Query: 888 TTELEEFKEAFAGAVKANNSMSK 910
++E ++ A A+ ++ K
Sbjct: 603 EADIESYQSRLAAAISKHSESVK 625
>gi|239757009 PREDICTED: ankyrin repeat domain 20 family, member A5
[Homo sapiens]
Length = 823
Score = 353 bits (906), Expect = 4e-97
Identities = 306/936 (32%), Positives = 461/936 (49%), Gaps = 133/936 (14%)
Query: 3 KLFSFGRRLGQALLSSMDQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLD 62
KLF F R GQ +L S+D Y G GY IR EL+KIH+AA+KGDAAE+ERCL RR DLD
Sbjct: 2 KLFGFRSRRGQTVLGSIDHLYTGSGYRIRYSELQKIHKAAVKGDAAEMERCLARRSGDLD 61
Query: 63 ARDRKDRTVLHLACAHGRVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLE 122
A D++ RT LHLACA G V+VVTLL++R+CQIDI D+ NRTPL++AVH QEEACA++LLE
Sbjct: 62 ALDKQHRTALHLACASGHVKVVTLLVNRKCQIDIYDKENRTPLIQAVHCQEEACAVILLE 121
Query: 123 CGANPNIEDIYGNTALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHM 182
GANPN++DIYGNTALHYAVY++ TSLAE+LL H NIEAL+K+ NTPLLFAI +++ M
Sbjct: 122 HGANPNLKDIYGNTALHYAVYSESTSLAEKLLFHGENIEALDKDSNTPLLFAIICKKEKM 181
Query: 183 VEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALC 242
VEFLLKN+A+ HAVD + TAL+LAV ++ IV +LL+Q+I + +QDM G+ AEDYA+
Sbjct: 182 VEFLLKNKASTHAVDRLRXTALMLAVHYDSLGIVNILLKQSINVFTQDMCGRDAEDYAIS 241
Query: 243 SDLRSIRQQILEHKNKMLKNHLRN--DNQETAAMKPANLKKRKERAKAEHNLKVASEEKQ 300
L I+QQILEHK +LKN + + E+A L A + L VA+++
Sbjct: 242 CRLTKIQQQILEHKKMILKNDKPDVGSSDESAVSIFHELCVDSLSALDDELLSVAAKQ-- 299
Query: 301 ERLQRSENKQPQDSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYIQEIK 360
+ +P S+GK + G K E K+ SL K
Sbjct: 300 --CVPEKVSEPLRGPSHGKGNRIVNG-----------KGEGPPAKHPSL----------K 336
Query: 361 SITEINANFEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVE 420
TE+ K A + + L+AE A L E+E+ +ER E +
Sbjct: 337 PSTEMEDPAVKG------------AVQXKNVQTLRAEQA-LPVASEEEQQRRERSEKKQP 383
Query: 421 SLHSSLATAINEYNEIVERKDLELVLWRADDVSRHEKMGSNISQ-----LTDKNELLT-E 474
+ T +E ++ E AD +++ K+G Q L ++++ T +
Sbjct: 384 QVIEGNNTYKSEKIQLSENICHSTFSAAADRLTQQRKIGKTYPQQFPKKLKEEHDRCTLK 443
Query: 475 QVHKARVKFNTLKGKLRETRDALREKTLALGSVQLDLRQAQHRIK-EMKQMHPNGEAKES 533
Q ++ + N L K RE +L+ ++ Q++ + E KQ+ P ++ E
Sbjct: 444 QENEEKTNVNMLHKKNRE---------------ELERKEKQYKKEVEAKQLEPTVQSLEM 488
Query: 534 QSIGKQNSLEERIRQQELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERN 593
+ +N+ + E +++D E + I I R + K D LE+ N
Sbjct: 489 KPKTARNTPNQDFHNHE--------EVKDLMDENCILKTDIAILRQEICTMKNDNLEKEN 540
Query: 594 K-----ELMKEYNYLKEKLLQCEKEKAEREVIVREFQEELVDHLKTFSISESPLEGTSHC 648
K ++ KE N EK ++ +E + +Q+EL D LK +
Sbjct: 541 KYLKDIKIAKETNAALEKCIKLNEEMITKTAF--WYQQELND-LKA---------ENTRL 588
Query: 649 HINLNETWTSKKKLFQVEIQPEEKHEEFRKLFELISLLNYTADQIRKKNRELEEEATGYK 708
+ L + SKKKL + EI+ S + A I K + ++ E K
Sbjct: 589 NSELLKEKESKKKL-EAEIE---------------SYQSRLAAAISKHSENVKTE-RNLK 631
Query: 709 KCLEMTINMLNAF-ANEDFSCHGDLN---TDQL-KMDILFKKLKQKFNDLVAEKEAVSSE 763
LE T ++ + D S D N T+QL KM I F LK KF
Sbjct: 632 LALERTQDISEQVKMSSDISEIEDKNXFLTEQLSKMQIKFNTLKDKFR------------ 679
Query: 764 CVNLAKDNEVLHQELLSMRNVQEKCEKLEKDKKMLEEEVLNLKTHMEKDMVELGKLQEYK 823
K + L ++ L++ VQ + ++ K ++E + + + K + ++E
Sbjct: 680 -----KTRDTLRKKSLALETVQNDLSQTQQQIKEMKEMYQSAEAKVSKSTGKWNCVEERI 734
Query: 824 SELDERAVQEIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSKMKTA 883
+L ++L ++H Q E K++ + +KK+L L++ K K+
Sbjct: 735 CQLQRENPWLEQQLVDVH---QKEDHKEIVINIQRGFIESRKKDLMLEE---KNKKLMNE 788
Query: 884 YEEVTTELEEFKEAFAGAVKANNSMSKKLMKSDKKI 919
Y+ + L +++ A V + K S KK+
Sbjct: 789 YDHLKESLFQYERQKAETV-VSIKEDKYFQTSRKKV 823
>gi|239751523 PREDICTED: ankyrin repeat domain 20 family, member A5
[Homo sapiens]
Length = 823
Score = 353 bits (906), Expect = 4e-97
Identities = 306/936 (32%), Positives = 461/936 (49%), Gaps = 133/936 (14%)
Query: 3 KLFSFGRRLGQALLSSMDQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLD 62
KLF F R GQ +L S+D Y G GY IR EL+KIH+AA+KGDAAE+ERCL RR DLD
Sbjct: 2 KLFGFRSRRGQTVLGSIDHLYTGSGYRIRYSELQKIHKAAVKGDAAEMERCLARRSGDLD 61
Query: 63 ARDRKDRTVLHLACAHGRVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLE 122
A D++ RT LHLACA G V+VVTLL++R+CQIDI D+ NRTPL++AVH QEEACA++LLE
Sbjct: 62 ALDKQHRTALHLACASGHVKVVTLLVNRKCQIDIYDKENRTPLIQAVHCQEEACAVILLE 121
Query: 123 CGANPNIEDIYGNTALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHM 182
GANPN++DIYGNTALHYAVY++ TSLAE+LL H NIEAL+K+ NTPLLFAI +++ M
Sbjct: 122 HGANPNLKDIYGNTALHYAVYSESTSLAEKLLFHGENIEALDKDSNTPLLFAIICKKEKM 181
Query: 183 VEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALC 242
VEFLLKN+A+ HAVD + TAL+LAV ++ IV +LL+Q+I + +QDM G+ AEDYA+
Sbjct: 182 VEFLLKNKASTHAVDRLRXTALMLAVHYDSLGIVNILLKQSINVFTQDMCGRDAEDYAIS 241
Query: 243 SDLRSIRQQILEHKNKMLKNHLRN--DNQETAAMKPANLKKRKERAKAEHNLKVASEEKQ 300
L I+QQILEHK +LKN + + E+A L A + L VA+++
Sbjct: 242 CRLTKIQQQILEHKKMILKNDKPDVGSSDESAVSIFHELCVDSLSALDDELLSVAAKQ-- 299
Query: 301 ERLQRSENKQPQDSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYIQEIK 360
+ +P S+GK + G K E K+ SL K
Sbjct: 300 --CVPEKVSEPLRGPSHGKGNRIVNG-----------KGEGPPAKHPSL----------K 336
Query: 361 SITEINANFEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVE 420
TE+ K A + + L+AE A L E+E+ +ER E +
Sbjct: 337 PSTEMEDPAVKG------------AVQXKNVQTLRAEQA-LPVASEEEQQRRERSEKKQP 383
Query: 421 SLHSSLATAINEYNEIVERKDLELVLWRADDVSRHEKMGSNISQ-----LTDKNELLT-E 474
+ T +E ++ E AD +++ K+G Q L ++++ T +
Sbjct: 384 QVIEGNNTYKSEKIQLSENICHSTFSAAADRLTQQRKIGKTYPQQFPKKLKEEHDRCTLK 443
Query: 475 QVHKARVKFNTLKGKLRETRDALREKTLALGSVQLDLRQAQHRIK-EMKQMHPNGEAKES 533
Q ++ + N L K RE +L+ ++ Q++ + E KQ+ P ++ E
Sbjct: 444 QENEEKTNVNMLHKKNRE---------------ELERKEKQYKKEVEAKQLEPTVQSLEM 488
Query: 534 QSIGKQNSLEERIRQQELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERN 593
+ +N+ + E +++D E + I I R + K D LE+ N
Sbjct: 489 KPKTARNTPNQDFHNHE--------EVKDLMDENCILKTDIAILRQEICTMKNDNLEKEN 540
Query: 594 K-----ELMKEYNYLKEKLLQCEKEKAEREVIVREFQEELVDHLKTFSISESPLEGTSHC 648
K ++ KE N EK ++ +E + +Q+EL D LK +
Sbjct: 541 KYLKDIKIAKETNAALEKCIKLNEEMITKTAF--WYQQELND-LKA---------ENTRL 588
Query: 649 HINLNETWTSKKKLFQVEIQPEEKHEEFRKLFELISLLNYTADQIRKKNRELEEEATGYK 708
+ L + SKKKL + EI+ S + A I K + ++ E K
Sbjct: 589 NSELLKEKESKKKL-EAEIE---------------SYQSRLAAAISKHSENVKTE-RNLK 631
Query: 709 KCLEMTINMLNAF-ANEDFSCHGDLN---TDQL-KMDILFKKLKQKFNDLVAEKEAVSSE 763
LE T ++ + D S D N T+QL KM I F LK KF
Sbjct: 632 LALERTQDISEQVKMSSDISEIEDKNXFLTEQLSKMQIKFNTLKDKFR------------ 679
Query: 764 CVNLAKDNEVLHQELLSMRNVQEKCEKLEKDKKMLEEEVLNLKTHMEKDMVELGKLQEYK 823
K + L ++ L++ VQ + ++ K ++E + + + K + ++E
Sbjct: 680 -----KTRDTLRKKSLALETVQNDLSQTQQQIKEMKEMYQSAEAKVSKSTGKWNCVEERI 734
Query: 824 SELDERAVQEIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSKMKTA 883
+L ++L ++H Q E K++ + +KK+L L++ K K+
Sbjct: 735 CQLQRENPWLEQQLVDVH---QKEDHKEIVINIQRGFIESRKKDLMLEE---KNKKLMNE 788
Query: 884 YEEVTTELEEFKEAFAGAVKANNSMSKKLMKSDKKI 919
Y+ + L +++ A V + K S KK+
Sbjct: 789 YDHLKESLFQYERQKAETV-VSIKEDKYFQTSRKKV 823
>gi|239756999 PREDICTED: ankyrin repeat domain 62 [Homo sapiens]
Length = 917
Score = 283 bits (724), Expect = 6e-76
Identities = 263/933 (28%), Positives = 442/933 (47%), Gaps = 118/933 (12%)
Query: 23 YAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLDARDRKDRTVLHLACAHGRVQ 82
++ PGY +R +L IH+AAI GD +V + R DL+ RD+K+RT L LACAHGR
Sbjct: 27 FSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILLRLNDLNDRDKKNRTALLLACAHGRPG 86
Query: 83 VVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLECGANPNIEDIYGNTALHYAV 142
VV L+ R+CQ+++ D NRT L+KAV QEE CA +LLE GANPN+ D+YGNTALHYA+
Sbjct: 87 VVADLVARKCQLNLTDSENRTALIKAVQCQEEVCASILLEHGANPNVRDMYGNTALHYAI 146
Query: 143 YNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNFKRT 202
N+ S+A +LL++ A+IEA +++G+T LL A+N +++ MV FLLK + ++ A+DNF RT
Sbjct: 147 DNENISMARKLLAYGADIEARSQDGHTSLLLAVNRKKEQMVSFLLKKKPDLTAIDNFGRT 206
Query: 203 ALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQILEHKNKMLKN 262
ALILA ++ +S+V LLQ NI + QD+ G TAEDYA+ S ++IR I E+K +
Sbjct: 207 ALILAARNGSTSVVYQLLQHNIDVFCQDISGWTAEDYAVASKFQAIRGMISEYKANKRRK 266
Query: 263 HLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQDSQSYGKKKD 322
L+N N +E +L++ SE +QERL+ E+ QPQ + K K
Sbjct: 267 SLQNSN-------------------SEQDLEMTSEGEQERLEGCESSQPQVEE---KMKK 304
Query: 323 AMYGNFMLKKDIAMLKEELYAIKNDSL--RKEKKYIQEIKSITEINANFEKSVR--LNEK 378
+ +++ + Y D L + + + +S + N F++ R NEK
Sbjct: 305 CRNKKMEVSRNVHADDSDNYNDDVDELIHKIKNRKPDNHQSPGKENGEFDRLARKTSNEK 364
Query: 379 MITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVESLHSSLATAINEYNEIVE 438
K+ ++ LND+ + + + + E + E L ++ + +
Sbjct: 365 SKVKSQIYFTDDLNDISGSSEKTSEDDELPYSDDENFML----LIKQSGMECKDFVSLSK 420
Query: 439 RKDLELVLWRADDVS---------RHEKMGSNISQL------TDKNELLTE-QVHKARVK 482
K+ R+ + + +KM +NIS L TDK + +E Q + + K
Sbjct: 421 SKNATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQKVLSETDKTKSQSEHQNLQGKKK 480
Query: 483 FNTLKGKLRETR------DALREKTLALGSVQLDLRQAQHRIKEMKQMHPNG---EAKES 533
L+ L++ + L EK + + + + Q +K+ ++ E K
Sbjct: 481 LCNLRFILQQQEEERIKAEELYEKDIEELKIMEEQYRTQTEVKKQSKLTLKSLEVELKTV 540
Query: 534 QSIGKQN-SLEERIRQQELENLLLERQLEDARKEGD-----NKEIVINIHRD--CLENGK 585
+S QN ER R EN L+ ++ R E D N+E +D ++
Sbjct: 541 RSNSNQNFHTHERERDLWQENHLMRDEIARLRLEIDTIKHQNQETENKYFKDIEIIKENN 600
Query: 586 EDLLE--ERNKELM--------KEYNYLKEK--LLQCEKEKAEREVIVREFQEE------ 627
EDL + +RN+E + KE N L ++ +L E +K ++ + E + E
Sbjct: 601 EDLEKTLKRNEETLTKTITRYSKELNVLMDENTMLNSELQKEKQSMSRLETEMESYRCRL 660
Query: 628 ---LVDHLKTFSIS---ESPLEGTSHCHINLNETWTSKKKLFQVEIQPEEKHEEFRKLFE 681
L DH + S + + T + +L E S ++ ++ E
Sbjct: 661 AAALCDHDQRQSSKRDLQLAFQSTVNEWCHLQEDTNSHIQILSQQLSKAESTSS-----G 715
Query: 682 LISLLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDI 741
L + L+Y + +++K +E + ++ + + N+ + Q D
Sbjct: 716 LETELHYEREALKEKTLHIEHMQGVLSRTQRRLEDIEHMYQNDQPILEKYVRKQQSVEDG 775
Query: 742 LFKKLKQKFNDLVAEKEAVSSECVNLAKDNEVLHQELLSMRNVQEKC----EKLEKDKKM 797
LF+ L ++ +C + K + + ++ N+Q KC EKL+ + +
Sbjct: 776 LFQ--------LQSQNLLYQQQCNDARKKADNQEKTII---NIQVKCEDTVEKLQAECRK 824
Query: 798 LEEEVLNLKTHMEKDMVELGKLQEYKSELDERAV--QEIEKLEEIHLQKQAEYEKQLE-- 853
LEE N K M++ + + +Y+ E +ER V +++++ + L KQ E LE
Sbjct: 825 LEE---NNKGLMKECTLLKERQCQYEKEKEEREVVRRQLQREVDDALNKQLLLEAMLEIS 881
Query: 854 ---QLN-KDNTASLKKKELTLKDVECKFSKMKT 882
++N +D SLKKK ++ C M T
Sbjct: 882 SERRINLEDEAQSLKKKLGQMRSQVCMKLSMST 914
>gi|239751514 PREDICTED: ankyrin repeat domain 62 isoform 4 [Homo
sapiens]
Length = 917
Score = 283 bits (724), Expect = 6e-76
Identities = 263/933 (28%), Positives = 442/933 (47%), Gaps = 118/933 (12%)
Query: 23 YAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLDARDRKDRTVLHLACAHGRVQ 82
++ PGY +R +L IH+AAI GD +V + R DL+ RD+K+RT L LACAHGR
Sbjct: 27 FSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILLRLNDLNDRDKKNRTALLLACAHGRPG 86
Query: 83 VVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLECGANPNIEDIYGNTALHYAV 142
VV L+ R+CQ+++ D NRT L+KAV QEE CA +LLE GANPN+ D+YGNTALHYA+
Sbjct: 87 VVADLVARKCQLNLTDSENRTALIKAVQCQEEVCASILLEHGANPNVRDMYGNTALHYAI 146
Query: 143 YNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNFKRT 202
N+ S+A +LL++ A+IEA +++G+T LL A+N +++ MV FLLK + ++ A+DNF RT
Sbjct: 147 DNENISMARKLLAYGADIEARSQDGHTSLLLAVNRKKEQMVSFLLKKKPDLTAIDNFGRT 206
Query: 203 ALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQILEHKNKMLKN 262
ALILA ++ +S+V LLQ NI + QD+ G TAEDYA+ S ++IR I E+K +
Sbjct: 207 ALILAARNGSTSVVYQLLQHNIDVFCQDISGWTAEDYAVASKFQAIRGMISEYKANKRRK 266
Query: 263 HLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQDSQSYGKKKD 322
L+N N +E +L++ SE +QERL+ E+ QPQ + K K
Sbjct: 267 SLQNSN-------------------SEQDLEMTSEGEQERLEGCESSQPQVEE---KMKK 304
Query: 323 AMYGNFMLKKDIAMLKEELYAIKNDSL--RKEKKYIQEIKSITEINANFEKSVR--LNEK 378
+ +++ + Y D L + + + +S + N F++ R NEK
Sbjct: 305 CRNKKMEVSRNVHADDSDNYNDDVDELIHKIKNRKPDNHQSPGKENGEFDRLARKTSNEK 364
Query: 379 MITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVESLHSSLATAINEYNEIVE 438
K+ ++ LND+ + + + + E + E L ++ + +
Sbjct: 365 SKVKSQIYFTDDLNDISGSSEKTSEDDELPYSDDENFML----LIKQSGMECKDFVSLSK 420
Query: 439 RKDLELVLWRADDVS---------RHEKMGSNISQL------TDKNELLTE-QVHKARVK 482
K+ R+ + + +KM +NIS L TDK + +E Q + + K
Sbjct: 421 SKNATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQKVLSETDKTKSQSEHQNLQGKKK 480
Query: 483 FNTLKGKLRETR------DALREKTLALGSVQLDLRQAQHRIKEMKQMHPNG---EAKES 533
L+ L++ + L EK + + + + Q +K+ ++ E K
Sbjct: 481 LCNLRFILQQQEEERIKAEELYEKDIEELKIMEEQYRTQTEVKKQSKLTLKSLEVELKTV 540
Query: 534 QSIGKQN-SLEERIRQQELENLLLERQLEDARKEGD-----NKEIVINIHRD--CLENGK 585
+S QN ER R EN L+ ++ R E D N+E +D ++
Sbjct: 541 RSNSNQNFHTHERERDLWQENHLMRDEIARLRLEIDTIKHQNQETENKYFKDIEIIKENN 600
Query: 586 EDLLE--ERNKELM--------KEYNYLKEK--LLQCEKEKAEREVIVREFQEE------ 627
EDL + +RN+E + KE N L ++ +L E +K ++ + E + E
Sbjct: 601 EDLEKTLKRNEETLTKTITRYSKELNVLMDENTMLNSELQKEKQSMSRLETEMESYRCRL 660
Query: 628 ---LVDHLKTFSIS---ESPLEGTSHCHINLNETWTSKKKLFQVEIQPEEKHEEFRKLFE 681
L DH + S + + T + +L E S ++ ++ E
Sbjct: 661 AAALCDHDQRQSSKRDLQLAFQSTVNEWCHLQEDTNSHIQILSQQLSKAESTSS-----G 715
Query: 682 LISLLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDI 741
L + L+Y + +++K +E + ++ + + N+ + Q D
Sbjct: 716 LETELHYEREALKEKTLHIEHMQGVLSRTQRRLEDIEHMYQNDQPILEKYVRKQQSVEDG 775
Query: 742 LFKKLKQKFNDLVAEKEAVSSECVNLAKDNEVLHQELLSMRNVQEKC----EKLEKDKKM 797
LF+ L ++ +C + K + + ++ N+Q KC EKL+ + +
Sbjct: 776 LFQ--------LQSQNLLYQQQCNDARKKADNQEKTII---NIQVKCEDTVEKLQAECRK 824
Query: 798 LEEEVLNLKTHMEKDMVELGKLQEYKSELDERAV--QEIEKLEEIHLQKQAEYEKQLE-- 853
LEE N K M++ + + +Y+ E +ER V +++++ + L KQ E LE
Sbjct: 825 LEE---NNKGLMKECTLLKERQCQYEKEKEEREVVRRQLQREVDDALNKQLLLEAMLEIS 881
Query: 854 ---QLN-KDNTASLKKKELTLKDVECKFSKMKT 882
++N +D SLKKK ++ C M T
Sbjct: 882 SERRINLEDEAQSLKKKLGQMRSQVCMKLSMST 914
>gi|239746016 PREDICTED: ankyrin repeat domain 62 isoform 1 [Homo
sapiens]
Length = 917
Score = 282 bits (722), Expect = 1e-75
Identities = 263/933 (28%), Positives = 442/933 (47%), Gaps = 118/933 (12%)
Query: 23 YAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLDARDRKDRTVLHLACAHGRVQ 82
++ PGY +R +L IH+AAI GD +V + R DL+ RD+K+RT L LACAHGR
Sbjct: 27 FSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILLRLNDLNDRDKKNRTALLLACAHGRPG 86
Query: 83 VVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLECGANPNIEDIYGNTALHYAV 142
VV L+ R+CQ+++ D NRT L+KAV QEE CA +LLE GANPN+ D+YGNTALHYA+
Sbjct: 87 VVADLVARKCQLNLTDSENRTALIKAVQCQEEVCASILLEHGANPNVRDMYGNTALHYAI 146
Query: 143 YNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNFKRT 202
N+ S+A +LL++ A+IEA +++G+T LL A+N +++ MV FLLK + ++ A+DNF RT
Sbjct: 147 DNENISMARKLLAYGADIEARSQDGHTSLLLAVNRKKEQMVAFLLKKKPDLTAIDNFGRT 206
Query: 203 ALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQILEHKNKMLKN 262
ALILA ++ +S+V LLQ NI + QD+ G TAEDYA+ S ++IR I E+K
Sbjct: 207 ALILAARNGSTSVVYQLLQHNIDVFCQDISGWTAEDYAVASKFQAIRGMISEYKANKRCK 266
Query: 263 HLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQDSQSYGKKKD 322
L+N N +E +L++ SE +QERL+ E+ QPQ + K K
Sbjct: 267 SLQNSN-------------------SEQDLEMTSEGEQERLEGCESSQPQVEE---KMKK 304
Query: 323 AMYGNFMLKKDIAMLKEELYAIKNDSL--RKEKKYIQEIKSITEINANFEKSVR--LNEK 378
+ +++ + Y D L + + + +S + N F++ R NEK
Sbjct: 305 CRNKKMEVSRNVHADDSDNYNDDVDELIHKIKNRKPDNHQSPGKENGEFDRLARKTSNEK 364
Query: 379 MITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVESLHSSLATAINEYNEIVE 438
K+ ++ LND+ + + + + E + E +E ++ + +
Sbjct: 365 SKVKSQIYFTDDLNDISGSSEKTSEDDELPYSDDENFMLLIE----QSGMECKDFVSLSK 420
Query: 439 RKDLELVLWRADDVS---------RHEKMGSNISQL------TDKNELLTE-QVHKARVK 482
K+ R+ + + +KM +NIS L TDK + +E Q + + K
Sbjct: 421 SKNATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQKVLSETDKTKSQSEHQNLQGKKK 480
Query: 483 FNTLKGKLRETR------DALREKTLALGSVQLDLRQAQHRIKEMKQMHPNG---EAKES 533
L+ L++ + L EK + + + + Q +K+ ++ E K
Sbjct: 481 LCNLRFILQQQEEERIKAEELYEKDIEELKIMEEQYRTQTEVKKQSKLTLKSLEVELKTV 540
Query: 534 QSIGKQN-SLEERIRQQELENLLLERQLEDARKEGD-----NKEIVINIHRD--CLENGK 585
+S QN ER R EN L+ ++ R E D N+E +D ++
Sbjct: 541 RSNSNQNFHTHERERDLWQENHLMRDEIARLRLEIDTIKHQNQETENKYFKDIEIIKENN 600
Query: 586 EDLLE--ERNKELM--------KEYNYLKEK--LLQCEKEKAEREVIVREFQEE------ 627
EDL + +RN+E + KE N L ++ +L E +K ++ + E + E
Sbjct: 601 EDLEKTLKRNEEALTKTITRYSKELNVLMDENTMLNSELQKEKQSMSRLETEMESYRCRL 660
Query: 628 ---LVDHLKTFSIS---ESPLEGTSHCHINLNETWTSKKKLFQVEIQPEEKHEEFRKLFE 681
L DH + S + + T + +L E S ++ ++ E
Sbjct: 661 AAALCDHDQRQSSKRDLQLAFQSTVNEWCHLQEDTNSHIQILSQQLSKAESTSS-----G 715
Query: 682 LISLLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDI 741
L + L+Y + +++K +E + ++ + + N+ + Q D
Sbjct: 716 LETELHYEREALKEKTLHIEHMQGVLSRTQRRLEDIEHMYQNDQPILEKYVRKQQSVEDG 775
Query: 742 LFKKLKQKFNDLVAEKEAVSSECVNLAKDNEVLHQELLSMRNVQEKC----EKLEKDKKM 797
LF+ L ++ +C + K + + ++ N+Q KC EKL+ + +
Sbjct: 776 LFQ--------LQSQNLLYQQQCNDARKKADNQEKTII---NIQVKCEDTVEKLQAECRK 824
Query: 798 LEEEVLNLKTHMEKDMVELGKLQEYKSELDERAV--QEIEKLEEIHLQKQAEYEKQLE-- 853
LEE N K M++ + + +Y+ E +ER V +++++ + L KQ E LE
Sbjct: 825 LEE---NNKGLMKECTLLKERQCQYEKEKEEREVVRRQLQREVDDALNKQLLLEAMLEIS 881
Query: 854 ---QLN-KDNTASLKKKELTLKDVECKFSKMKT 882
++N +D SLKKK ++ C M T
Sbjct: 882 SERRINLEDEAQSLKKKLGQMRSQVCMKLSMST 914
>gi|149363642 coiled-coil domain containing 144A [Homo sapiens]
Length = 1427
Score = 268 bits (684), Expect = 2e-71
Identities = 237/869 (27%), Positives = 411/869 (47%), Gaps = 167/869 (19%)
Query: 138 LHYAVYNKGTSLAERLLSHHANIEALNKEGNT----PLLFAINSRRQHMVEFLLKNQANI 193
L ++VY L E+L + + +L + +T L + + + LK N+
Sbjct: 610 LSHSVYENFMLLIEQLRMEYKDSASLPRIQDTFCLCEHLLKLKNNHCDQLTVKLKQMENM 669
Query: 194 HAV-----DNFKRTALILAVQH-----NLSSIVTLLLQQNIRISSQDM-FGQTAEDYAL- 241
+V K+T L L +Q L + L Q+N + DM + + +E +
Sbjct: 670 VSVLQNELSETKKTKLQLELQKIEWEKELYDLRLALKQENEEKRNADMLYNKDSEQLRIK 729
Query: 242 ---CSDLRSIRQQILEHKNKMLKNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEE 298
C + +QQ+ + +++K N ++ N +++ E + ++ ++
Sbjct: 730 EEECGKVVETKQQLKWNLRRLVKELRTVRNNLDLVVQERN--DAQKQLSEEQDARILQDQ 787
Query: 299 ----KQERLQRSENKQPQD-SQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEK 353
KQ+ L+ + K + S + K+KD + + ML+++IA+L+ E+ IKN + +KEK
Sbjct: 788 ILTSKQKELEMARKKMNSEISHRHQKEKDLFHEDCMLQEEIALLRLEIDTIKNQNKQKEK 847
Query: 354 KYIQEIKSITEINANFEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKE 413
KY ++I+++ E N N +K ++LNE+ +T+T+ +YS QLN+L AEN LNSELE K N+E
Sbjct: 848 KYFEDIEAVKEKNDNLQKIIKLNEETLTETILQYSGQLNNLTAENKILNSELENGKQNQE 907
Query: 414 RLEAEVESLHSSLATAINEYNEIVERKDLELVLWRA--DDVSRHEKMGSNISQLTDKNEL 471
RLE E+ES LA A+ + ++ +DL+L R + V H+KM ++S L KNE+
Sbjct: 908 RLEIEMESYRCRLAAAVRDCDQSQTARDLKLDFQRTRQEWVRLHDKMKVDMSGLQAKNEI 967
Query: 472 LTEQVHKARVKFNTLKGKLRETRDALREKTLALGSVQLDLRQAQHRIKEMKQMHPNGEAK 531
L+E++ A K N+L+ +L TRDAL ++L L VQ DL Q Q + KE +QM+ ++K
Sbjct: 968 LSEKLSNAESKINSLQIQLHNTRDALGRESLILERVQRDLSQTQCQKKETEQMYQIEQSK 1027
Query: 532 ESQSIGKQNSLEERIRQQELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDL--- 588
+ I KQ S+EER+ Q + EN+LL +QL+DA K+ +++E + +D + ++L
Sbjct: 1028 LKKYIAKQESVEERLSQLQSENMLLRQQLDDAHKKANSQEKTSSTIQDQFHSAAKNLQAE 1087
Query: 589 -------LEERNKELMKEYNYLKEKLLQCEKEKAEREVIVREFQEELVDHLKTFSISESP 641
L+E+NKELM EYN+LKE++ QCEKEKA R++ + E QE +
Sbjct: 1088 SEKQILSLQEKNKELMDEYNHLKERMDQCEKEKAGRKIDLTEAQETV------------- 1134
Query: 642 LEGTSHC-HINL-NETWTSKKKLFQVEIQPEEKHEEFRKLFELISLLNYTADQIRKKNRE 699
S C H++ NE ++ LF ++ + + ++K ++
Sbjct: 1135 ---PSRCLHLDAENEVLQLQQTLFSMK------------------AIQKQCETLQKNKKQ 1173
Query: 700 LEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEA 759
L++E K +E NML E H L ++ + K++++K N+ +
Sbjct: 1174 LKQEVVNLKSYMER--NMLERGKAE---WHKLLIEERAR-----KEIEEKLNEAI----- 1218
Query: 760 VSSECVNLAKDNEVLHQELLSMRNVQEKCEKLEKDKKMLEEEVLNLKTHMEKDMVEL-GK 818
+ L K V H++L+ +R E+ ++KT ME + +L +
Sbjct: 1219 -----LTLQKQAAVSHEQLVQLR----------------EDNTTSIKTQMELTIKDLESE 1257
Query: 819 LQEYKSELDERAVQEIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVECKFS 878
+ K+ + E+E+ +E++L++ E +L++ N
Sbjct: 1258 ISRIKTSQADFNKTELERYKELYLEEVKVRESLSNELSRTN------------------- 1298
Query: 879 KMKTAYEEVTTELEEFKEAFAGAVKANNSMSKKLMKSDKKIAVISTKLFMEKERMEYFLS 938
EV+T+L KE + R +
Sbjct: 1299 ---EMIAEVSTQLTVEKE---------------------------------QTRSRSLFT 1322
Query: 939 TLPMRPDPELPCVENLNSIE-LNRKYIPK 966
RP E PCV NLN E LNRK+IP+
Sbjct: 1323 AYATRPVLESPCVGNLNDSEGLNRKHIPR 1351
Score = 60.1 bits (144), Expect = 1e-08
Identities = 132/708 (18%), Positives = 295/708 (41%), Gaps = 83/708 (11%)
Query: 265 RNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQDSQSYGKKKDAM 324
+N NQ + + N K K + + +L S+ E E +Q D Q +
Sbjct: 452 KNMNQNSDSGSTNNYKSLKPKLENLSSLPPDSDRTSEVYLHEELQQ--DMQKF------- 502
Query: 325 YGNFMLKKDIAMLKEELYAIKNDSLRKEKKYIQEIK----SITEINANFEKSVR------ 374
K ++ L+EE A+K + ++ K +E++ + TE++
Sbjct: 503 ------KNEVNTLEEEFLALKKEDVQLHKDVEEEMEKHRSNSTELSGTLTDGTTVGNDDD 556
Query: 375 -LNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLE-AEVESLHSSLATAINE 432
LN+++ K + + + E + +++ E + +E +E+ S L+ ++ E
Sbjct: 557 GLNQQIPRKENGEHDRPADKTSNEKNEVKNQIYPEADFADSMEPSEIASEDCELSHSVYE 616
Query: 433 YNEIVERKDLELVLWRADDVSRHEK---MGSNISQLTDKN-ELLTEQVHKARVKFNTLKG 488
N ++ + L + + + R + + ++ +L + + + LT ++ + + L+
Sbjct: 617 -NFMLLIEQLRMEYKDSASLPRIQDTFCLCEHLLKLKNNHCDQLTVKLKQMENMVSVLQN 675
Query: 489 KLRETRDALREKTLALGSVQLDLRQAQHRIKEMKQMHPNGEAKESQSIGKQNSLEERIRQ 548
+L ET+ + L + +L + +K+ N E + + + ++S + RI++
Sbjct: 676 ELSETKKTKLQLELQKIEWEKELYDLRLALKQ-----ENEEKRNADMLYNKDSEQLRIKE 730
Query: 549 QELENLL---------LERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKELMKE 599
+E ++ L R +++ R +N ++V+ D ++ L EE++ ++++
Sbjct: 731 EECGKVVETKQQLKWNLRRLVKELRTVRNNLDLVVQERND----AQKQLSEEQDARILQD 786
Query: 600 YNYL-KEKLLQCEKEKAEREVIVREFQEELVDHLKTFSISESPLEGTSHCHINLNETWTS 658
K+K L+ ++K E+ R +E+ + H E L I N+
Sbjct: 787 QILTSKQKELEMARKKMNSEISHRHQKEKDLFHEDCMLQEEIALLRLEIDTIK-NQNKQK 845
Query: 659 KKKLFQVEIQPEEKHEEFRKLFEL------ISLLNYTA--DQIRKKNRELEEEATGYKKC 710
+KK F+ +EK++ +K+ +L ++L Y+ + + +N+ L E K+
Sbjct: 846 EKKYFEDIEAVKEKNDNLQKIIKLNEETLTETILQYSGQLNNLTAENKILNSELENGKQN 905
Query: 711 LE-MTINMLN---AFANEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSECVN 766
E + I M + A C LK+D F++ +Q++ V + + +
Sbjct: 906 QERLEIEMESYRCRLAAAVRDCDQSQTARDLKLD--FQRTRQEW---VRLHDKMKVDMSG 960
Query: 767 LAKDNEVLHQELLSMRNVQEKCEKLEKDKKMLEEEVLNLKTHMEKDMVELGKLQEYKSEL 826
L NE+L ++L N + K L+ + + +E+ +L + Q K E
Sbjct: 961 LQAKNEILSEKL---SNAESKINSLQIQLHNTRDALGRESLILERVQRDLSQTQCQKKET 1017
Query: 827 DERAVQEIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSKMKTAYEE 886
++ E KL++ ++ KQ E++L QL +N L + ++ K + +
Sbjct: 1018 EQMYQIEQSKLKK-YIAKQESVEERLSQLQSENM-------LLRQQLDDAHKKANSQEKT 1069
Query: 887 VTTELEEFKEAFAGAVKANNSMSKKLMKSDKKIAVISTKLFMEKERME 934
+T ++F A A K+++ +K + + KERM+
Sbjct: 1070 SSTIQDQFHSA---AKNLQAESEKQILSLQEKNKELMDEYNHLKERMD 1114
Score = 38.9 bits (89), Expect = 0.024
Identities = 18/36 (50%), Positives = 26/36 (72%)
Query: 277 ANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQ 312
+ L + KE +AE + ++ SEE+QERL+ ENKQPQ
Sbjct: 211 SQLPENKESKEAEQDSELTSEEEQERLKGCENKQPQ 246
Score = 34.7 bits (78), Expect = 0.46
Identities = 18/42 (42%), Positives = 24/42 (57%)
Query: 26 PGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLDARDRK 67
P +D+R +L ++HRAA GD VE L +D RDRK
Sbjct: 72 PQHDVRLEDLGELHRAARSGDVPGVEHILAPGDTGVDKRDRK 113
>gi|239741279 PREDICTED: similar to FLJ00310 protein [Homo sapiens]
Length = 561
Score = 253 bits (645), Expect = 8e-67
Identities = 203/592 (34%), Positives = 292/592 (49%), Gaps = 169/592 (28%)
Query: 270 ETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQDSQSYGKKKDAMYGNFM 329
E A+K A +K + +AE L VA EE+QER +RSE KQ Q +
Sbjct: 131 EDPAVKGAVQRKNVQTLRAEQTLPVALEEEQERCERSEKKQSQVKEG------------- 177
Query: 330 LKKDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEKMITKTVARYSQ 389
N++ + EK IQ +++ ++ ++ + KT Y Q
Sbjct: 178 ----------------NNTNKSEK--IQLSENVCHSTSSAAADRLTKQRKVGKT---YPQ 216
Query: 390 QLNDLKAENARLNSELEKEKHNKERLEAEVESLHSSLATAINEYNEIVERKDLELVLWRA 449
Q +L+KE H++E LE + + +Y + VE K LE +
Sbjct: 217 QFP----------KKLKKE-HDREELERKEK-----------QYKKEVEAKQLEPTVQSL 254
Query: 450 DDVSRHEKMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALR---EKTLALGS 506
D +K T + + +LR +K + +
Sbjct: 255 D------------------------------MKLKTTRNTPNQINQSLRYSQKKVIGFRN 284
Query: 507 VQLDLRQAQHRIKEMKQMHPNGEAKESQSIGKQNSLEERIRQQELENLLLERQLEDARKE 566
DL Q Q +IKEMK+M+ N EAK + S GK + +EERI Q + EN +E+QL+D ++
Sbjct: 285 SPNDLSQTQQQIKEMKEMYENAEAKVNNSTGKWSCVEERICQLQHENPCIEQQLDDVHQK 344
Query: 567 GDNKEIVINIHRDCLENGKEDLLEERNKELMKEYNYLKEKLLQCEKEKAEREVIVREFQE 626
D+KEIV NI R +E+GK+DL+ ++E N K+ + +C
Sbjct: 345 EDHKEIVTNIQRGFIESGKKDLM-------LEEKN--KKLMNEC---------------- 379
Query: 627 ELVDHLKTFSISESPLEGTSHCHINLNETWTSKKKLFQVEIQPEEKHEEFRKLFELISLL 686
DHLK + LFQ E R+ E + ++
Sbjct: 380 ---DHLK--------------------------ESLFQYE----------REKAERVVVV 400
Query: 687 NYTADQIRKKNRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKL 746
R+L++EA K L M + L ++ H +L+ Q+ LF+ +
Sbjct: 401 -----------RQLQQEAADSLKKLTMLESPLEGISHY----HINLDETQVPKKKLFQ-V 444
Query: 747 KQKFNDLVAEKEAVSSECVNLAKDNEVLHQELLSMRNVQEKCEKLEKDKKMLEEEVLNLK 806
+ +F+D +AEKEAVSS+CVNLAK+ +V QELLSM+ VQ++CEKLE+DKKMLEEE+LNLK
Sbjct: 445 ESQFDDFMAEKEAVSSKCVNLAKEIQVFQQELLSMKKVQQECEKLEEDKKMLEEEILNLK 504
Query: 807 THMEKDMVELGKLQEYKSELDERAVQEIEKLEEIHLQKQAEYEKQLEQLNKD 858
THME MVEL KLQEYKSELDERA+Q +EKLEEIHLQ+QAE++KQLEQLNKD
Sbjct: 505 THMENSMVELSKLQEYKSELDERAMQAVEKLEEIHLQEQAEHKKQLEQLNKD 556
>gi|53828703 POTE ankyrin domain family, member A isoform 2 [Homo
sapiens]
Length = 498
Score = 248 bits (633), Expect = 2e-65
Identities = 137/292 (46%), Positives = 192/292 (65%), Gaps = 20/292 (6%)
Query: 20 DQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLDARDRKDRTVLHLACAHG 79
D + P Y +R +L K+HRAA G+ + + R ++ RD+K RT LHLACA+G
Sbjct: 51 DSAFTEPRYHVRREDLGKLHRAAWWGEVPRADLIVMLRGPGINKRDKKKRTALHLACANG 110
Query: 80 RVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLECGANPNIEDIYGNTALH 139
+VV+LLL R+CQ+ + D RT L+KAV QE+ CA++LL+ G +PN+ D+YGNTALH
Sbjct: 111 NSEVVSLLLDRQCQLHVFDSKKRTALIKAVQCQEDECALMLLQHGTDPNLPDMYGNTALH 170
Query: 140 YAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNF 199
YAVYN+ +A+ LL + A+IE+ NK G TPLL A++ ++Q MV+FL+K +AN++A+D F
Sbjct: 171 YAVYNEDKLMAKTLLLYGADIESKNKGGLTPLLLAVHGQKQRMVKFLIKKKANLNALDRF 230
Query: 200 KRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQILEHK-NK 258
RTALILAV+ +SIV+LLLQQNI + SQD+FGQTAEDYA+ S I Q + ++K N+
Sbjct: 231 GRTALILAVRCGSASIVSLLLQQNIDVFSQDVFGQTAEDYAVSSHHSIICQLLSDYKENQ 290
Query: 259 MLKNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQ 310
M N N N E +LK+ SEE+ +RL+ SEN Q
Sbjct: 291 MPNNSSGNSN-------------------PEQDLKLTSEEEPQRLKGSENSQ 323
>gi|239745058 PREDICTED: hypothetical protein XP_002343353 [Homo
sapiens]
Length = 544
Score = 243 bits (620), Expect = 7e-64
Identities = 164/490 (33%), Positives = 261/490 (53%), Gaps = 55/490 (11%)
Query: 20 DQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLDARDRKDRTVLHLACAHG 79
D + P Y +R +L K+HRAA G + + R D++ RD++ RT LHLA A+G
Sbjct: 88 DSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQKRTALHLASANG 147
Query: 80 RVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLECGANPNIEDIYGNTALH 139
+VV LLL RRCQ+++ D RT L+KAV QE+ C ++LLE GA+ NI+D YGNTALH
Sbjct: 148 NSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADGNIQDEYGNTALH 207
Query: 140 YAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNF 199
YA+YN+ +A+ LL + A+IE+ NK G TPLL ++ ++Q +V+FL+K +AN++A+D +
Sbjct: 208 YAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQEVVKFLIKKKANLNALDRY 267
Query: 200 KRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQILEHKNKM 259
RTALILAV +SIV LLL+QN+ +SSQD+ GQTA +YA+ S I + + ++K K
Sbjct: 268 GRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDYKEKQ 327
Query: 260 LKNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQDSQSYGK 319
+ LK E + E +LK+ SEE+ +RL+ SEN QP+ +
Sbjct: 328 M------------------LKISSENSNPEQDLKLTSEEESQRLKVSENSQPEKMSQEPE 369
Query: 320 KKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEKM 379
+ KD EE + KK+ + E N + ++ +
Sbjct: 370 ----------INKDCDREVEE----------EIKKHGSNPVGLPENLTNGASAGNGDDGL 409
Query: 380 ITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVESLHSSLATAINEYNEIVER 439
I + +R K EN + +E H+ E+ + + + L T I++ +EI+
Sbjct: 410 IPQRKSR--------KPENQQFPDTENEEYHSDEQNDTQ-KQLSEEQNTGISQ-DEILTN 459
Query: 440 KDLELVLWRADDVSRHEKMGSNISQLTDKNELLTEQVHKARVKFNTLK-------GKLRE 492
K ++ + + S L +N +L E++ K R++ + K K+ E
Sbjct: 460 KQKQIEVAEKEMNSELSLSHKKEEDLLRENSMLREEIAKLRLELDETKHQNQLRENKILE 519
Query: 493 TRDALREKTL 502
++++EK L
Sbjct: 520 EIESVKEKLL 529
>gi|52856430 protein expressed in prostate, ovary, testis, and
placenta 15 [Homo sapiens]
Length = 581
Score = 241 bits (616), Expect = 2e-63
Identities = 163/490 (33%), Positives = 261/490 (53%), Gaps = 55/490 (11%)
Query: 20 DQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLDARDRKDRTVLHLACAHG 79
D + P Y +R +L K+HRAA G + + R D++ RD++ RT LHLA A+G
Sbjct: 125 DSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQKRTALHLASANG 184
Query: 80 RVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLECGANPNIEDIYGNTALH 139
+VV LLL RRCQ+++ D RT L+KAV QE+ C ++LLE GA+ NI+D YGNTALH
Sbjct: 185 NSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADGNIQDEYGNTALH 244
Query: 140 YAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNF 199
YA+YN+ +A+ LL + A+IE+ NK G TPLL ++ ++Q +V+FL+K +AN++A+D +
Sbjct: 245 YAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRY 304
Query: 200 KRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQILEHKNKM 259
RTALILAV +SIV LLL+QN+ +SSQD+ GQTA +YA+ S I + + ++K K
Sbjct: 305 GRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDYKEKQ 364
Query: 260 LKNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQDSQSYGK 319
+ LK E + E +LK+ SEE+ +RL+ SEN QP+ +
Sbjct: 365 M------------------LKISSENSNPEQDLKLTSEEESQRLKVSENSQPEKMSQEPE 406
Query: 320 KKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEKM 379
+ KD EE + KK+ + E N + ++ +
Sbjct: 407 ----------INKDCDREVEE----------EIKKHGSNPVGLPENLTNGASAGNGDDGL 446
Query: 380 ITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVESLHSSLATAINEYNEIVER 439
I + +R K EN + +E H+ E+ + + + L T I++ +EI+
Sbjct: 447 IPQRKSR--------KPENQQFPDTENEEYHSDEQNDTQ-KQLSEEQNTGISQ-DEILTN 496
Query: 440 KDLELVLWRADDVSRHEKMGSNISQLTDKNELLTEQVHKARVKFNTLK-------GKLRE 492
K ++ + + S+ L +N +L E++ R++ + K K+ E
Sbjct: 497 KQKQIEVAEKEMNSKLSLSHKKEEDLLRENSMLREEIAMLRLELDETKHQNQLRENKILE 556
Query: 493 TRDALREKTL 502
++++EK L
Sbjct: 557 EIESVKEKLL 566
>gi|209977003 ANKRD26-like family C, member 3 [Homo sapiens]
Length = 545
Score = 241 bits (616), Expect = 2e-63
Identities = 131/294 (44%), Positives = 189/294 (64%), Gaps = 18/294 (6%)
Query: 20 DQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLDARDRKDRTVLHLACAHG 79
D + P Y +R +L K+HRAA G + + + D++ +D++ RT LHLA A+G
Sbjct: 162 DSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLKDTDMNKKDKQKRTALHLASANG 221
Query: 80 RVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLECGANPNIEDIYGNTALH 139
+VV LLL RRCQ++I D RT L KAV QE+ CA++LLE G +PNI D YGNTALH
Sbjct: 222 NSEVVKLLLDRRCQLNILDNKKRTALTKAVQCQEDECALMLLEHGTDPNIPDEYGNTALH 281
Query: 140 YAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNF 199
YA+YN+ +A+ LL + A+IE+ NK G TPLL ++ ++Q +V+FL+K +AN++A+D +
Sbjct: 282 YAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRY 341
Query: 200 KRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQILEHKNKM 259
RTALILAV +SIV+LLL+QNI +SSQD+ GQTA +YA+ S I Q + ++K K
Sbjct: 342 GRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSRHNVICQLLSDYKEKQ 401
Query: 260 LKNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQD 313
+ LK E + E +LK+ SEE+ +RL+ SEN QP++
Sbjct: 402 I------------------LKVSSENSNPEQDLKLTSEEESQRLKGSENSQPEE 437
>gi|52856434 POTE ankyrin domain family, member G [Homo sapiens]
Length = 508
Score = 240 bits (613), Expect = 4e-63
Identities = 130/294 (44%), Positives = 189/294 (64%), Gaps = 18/294 (6%)
Query: 20 DQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLDARDRKDRTVLHLACAHG 79
D + P Y +R +L K+HRAA G + + + D++ +D++ RT LHLA A+G
Sbjct: 125 DSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLKDTDMNKKDKQKRTALHLASANG 184
Query: 80 RVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLECGANPNIEDIYGNTALH 139
+VV LLL RRCQ++I D RT L KAV +E+ CA++LLE G +PNI D YGNTALH
Sbjct: 185 NSEVVKLLLDRRCQLNILDNKKRTALTKAVQCREDECALMLLEHGTDPNIPDEYGNTALH 244
Query: 140 YAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNF 199
YA+YN+ +A+ LL + A+IE+ NK G TPLL ++ ++Q +V+FL+K +AN++A+D +
Sbjct: 245 YAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRY 304
Query: 200 KRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQILEHKNKM 259
RTALILAV +SIV+LLL+QNI +SSQD+ GQTA +YA+ S I Q + ++K K
Sbjct: 305 GRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHNVICQLLSDYKEKQ 364
Query: 260 LKNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQD 313
+ LK E + E +LK+ SEE+ +RL+ SEN QP++
Sbjct: 365 M------------------LKVSSENSNPEQDLKLTSEEESQRLKGSENSQPEE 400
>gi|239741769 PREDICTED: similar to protein expressed in prostate,
ovary, testis, and placenta 2 [Homo sapiens]
Length = 952
Score = 240 bits (613), Expect = 4e-63
Identities = 161/469 (34%), Positives = 248/469 (52%), Gaps = 51/469 (10%)
Query: 20 DQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLDARDRKDRTVLHLACAHG 79
D + P Y +R +L K+HRAA G A + + R D++ +D++ RT LHLA A+G
Sbjct: 125 DSAFVEPRYHVRREDLDKLHRAAWWGKVARKDLIVMLRDTDVNKQDKQKRTALHLASANG 184
Query: 80 RVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLECGANPNIEDIYGNTALH 139
VV LLL RRCQ+++ D RT L KAV QE+ CA++LLE G +PNI D YGNT LH
Sbjct: 185 NSGVVKLLLDRRCQLNVLDNKKRTALTKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLH 244
Query: 140 YAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNF 199
YA+YN+ +A+ LL + A+IE+ NK G TPLL ++ ++Q +V+FL+K +AN++A+D +
Sbjct: 245 YAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRY 304
Query: 200 KRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQILEHKNKM 259
RTALILAV +SIV+LLL+QNI +SSQD+ GQTA +YA+ S I Q + ++K K
Sbjct: 305 GRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQ 364
Query: 260 LKNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQD-SQSYG 318
+ LK E + E +LK+ SEE+ +R + SEN QP+ SQ
Sbjct: 365 M------------------LKISSENSNPEQDLKLTSEEESQRFKGSENSQPEKMSQEPE 406
Query: 319 KKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEK 378
KD G+ +++++ KK+ E N + ++
Sbjct: 407 INKD---GDREVEEEM------------------KKHGSTHVGFPENLTNGATAGNGDDG 445
Query: 379 MITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVESLHSSLATAINEYNEIVE 438
+I +R + EN +S+ + + + E LH + + E+VE
Sbjct: 446 LIPPRKSRTPESQQFPDTENEEYHSDEQNDTQKQFCEEQNTGILHDEILIHEEKQIEVVE 505
Query: 439 RKDLELVLWRADDVSRHEKMGSNISQLTDKNELLTEQVHKARVKFNTLK 487
+ + EL L + EK +N L E++ R++ +T+K
Sbjct: 506 KMNSELSL-----SCKKEK------DFLHENSTLREEIAMLRLELDTMK 543
Score = 77.8 bits (190), Expect = 5e-14
Identities = 82/384 (21%), Positives = 161/384 (41%), Gaps = 43/384 (11%)
Query: 29 DIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLDARDRKDRTVLHLACAHGRVQVVTLLL 88
++ D + R A++ E L D + D T LH A + + LL
Sbjct: 200 NVLDNKKRTALTKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLHYAIYNEDKLMAKALL 259
Query: 89 HRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLECGANPNIEDIYGNTALHYAVYNKGTS 148
I+ ++ TPL+ VH Q++ L++ AN N D YG TAL AV S
Sbjct: 260 LYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSAS 319
Query: 149 LAERLLSHHANIEALNKEGNTPLLFAINSRR----QHMVEFLLKNQANIHAVDNFKRTAL 204
+ LL + ++ + + G T +A++S Q + ++ K I + ++ L
Sbjct: 320 IVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQMLKISSENSNPEQDL 379
Query: 205 ILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQILEHKN------K 258
L + Q ++S + + + R + +++ +H + +
Sbjct: 380 KLTSEEESQRFKGSENSQPEKMSQEPEINKDGD--------REVEEEMKKHGSTHVGFPE 431
Query: 259 MLKNHLRNDNQETAAMKPANLKK---------------------RKERAKAEHNLKVASE 297
L N N + + P + +++ E N + +
Sbjct: 432 NLTNGATAGNGDDGLIPPRKSRTPESQQFPDTENEEYHSDEQNDTQKQFCEEQNTGILHD 491
Query: 298 E----KQERLQRSENKQPQDSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEK 353
E ++++++ E + S S K+KD ++ N L+++IAML+ EL +K+ S ++K
Sbjct: 492 EILIHEEKQIEVVEKMNSELSLSCKKEKDFLHENSTLREEIAMLRLELDTMKHQSQLRKK 551
Query: 354 KYIQEIKSITEINANFEKSVRLNE 377
KY+++I+S+ + N N K+++LNE
Sbjct: 552 KYLEDIESVKKKNDNLLKALQLNE 575
>gi|224282147 prostate-specific P704P [Homo sapiens]
Length = 508
Score = 240 bits (612), Expect = 6e-63
Identities = 130/294 (44%), Positives = 188/294 (63%), Gaps = 18/294 (6%)
Query: 20 DQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLDARDRKDRTVLHLACAHG 79
D + P Y +R +L K+HRAA G + + + D++ +D++ RT LHLA A+G
Sbjct: 125 DSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLKDTDMNKKDKQKRTALHLASANG 184
Query: 80 RVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLECGANPNIEDIYGNTALH 139
+VV LLL RRCQ++I D RT L KAV QE+ CA++LLE G +PNI D YGNTALH
Sbjct: 185 NSEVVKLLLDRRCQLNILDNKKRTALTKAVQCQEDECALMLLEHGTDPNIPDEYGNTALH 244
Query: 140 YAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNF 199
YA+YN+ +A+ LL + A+IE+ NK G TPLL ++ ++Q +V+FL+K +AN++A+D +
Sbjct: 245 YAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRY 304
Query: 200 KRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQILEHKNKM 259
RT LILAV +SIV+LLL+QNI +SSQD+ GQTA +YA+ S I Q + ++K K
Sbjct: 305 GRTVLILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSRHNVICQLLSDYKEKQ 364
Query: 260 LKNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQD 313
+ LK E + E +LK+ SEE+ +RL+ SEN QP++
Sbjct: 365 I------------------LKVSSENSNPEQDLKLTSEEESQRLKGSENSQPEE 400
>gi|134133226 protein expressed in prostate, ovary, testis, and
placenta 2 [Homo sapiens]
Length = 1075
Score = 239 bits (610), Expect = 9e-63
Identities = 133/304 (43%), Positives = 190/304 (62%), Gaps = 19/304 (6%)
Query: 20 DQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLDARDRKDRTVLHLACAHG 79
D + P Y +R +L K+HRAA G + + R D++ +D++ RT LHLA A+G
Sbjct: 125 DSAFMEPRYHVRGEDLDKLHRAAWWGKVPRKDLIVMLRDTDVNKKDKQKRTALHLASANG 184
Query: 80 RVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLECGANPNIEDIYGNTALH 139
+VV LLL RRCQ+++ D RT L+KAV QE+ CA++LLE G +PNI D YGNT LH
Sbjct: 185 NSEVVKLLLDRRCQLNVLDNKKRTALIKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLH 244
Query: 140 YAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNF 199
YA+YN+ +A+ LL + A+IE+ NK G TPLL ++ ++Q +V+FL+K +AN++A+D +
Sbjct: 245 YAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRY 304
Query: 200 KRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQILEHKNKM 259
RTALILAV +SIV+LLL+QNI +SSQD+ GQTA +YA+ S I Q + ++K K
Sbjct: 305 GRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQ 364
Query: 260 LKNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQD-SQSYG 318
+ LK E + E LK+ SEE+ +R + SEN QP+ SQ
Sbjct: 365 M------------------LKISSENSNPEQELKLTSEEESQRFKGSENSQPEKMSQELE 406
Query: 319 KKKD 322
KD
Sbjct: 407 INKD 410
Score = 59.3 bits (142), Expect = 2e-08
Identities = 39/128 (30%), Positives = 71/128 (55%), Gaps = 10/128 (7%)
Query: 250 QQILEHKNKMLKNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENK 309
QQ + +N+ + +ND Q+ ++ H+ + EEKQ ++ E
Sbjct: 581 QQFPDTENEEYHSDEQNDTQKQFC--------EEQNTGILHDEILIHEEKQ--IEVVEKM 630
Query: 310 QPQDSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANF 369
+ S S K+KD ++ N L+++IAML+ EL +K+ S +EKKY+++I+S+ + N N
Sbjct: 631 NSELSLSCKKEKDVLHENSTLREEIAMLRLELDTMKHQSQLREKKYLEDIESVKKKNDNL 690
Query: 370 EKSVRLNE 377
K+++LNE
Sbjct: 691 LKALQLNE 698
>gi|153791352 prostate, ovary, testis expressed protein on
chromosome 2 [Homo sapiens]
Length = 1075
Score = 239 bits (609), Expect = 1e-62
Identities = 129/293 (44%), Positives = 187/293 (63%), Gaps = 18/293 (6%)
Query: 20 DQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLDARDRKDRTVLHLACAHG 79
D + P Y +R +L K+HRAA G + + R D++ +D++ RT LHLA A+G
Sbjct: 125 DSAFMEPRYHVRGEDLDKLHRAAWWGKVPRKDLIVMLRDTDVNKQDKQKRTALHLASANG 184
Query: 80 RVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLECGANPNIEDIYGNTALH 139
+VV LLL RRCQ+++ D RT L+KAV QE+ CA++LLE G +PNI D YGNT LH
Sbjct: 185 NSEVVKLLLDRRCQLNVLDNKKRTALIKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLH 244
Query: 140 YAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNF 199
YA+YN+ +A+ LL + A+IE+ NK G TPLL ++ ++Q +V+FL+K +AN++A+D +
Sbjct: 245 YAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRY 304
Query: 200 KRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQILEHKNKM 259
RTALILAV +SIV+LLL+QNI +SSQD+ GQTA +YA+ S I Q + ++K K
Sbjct: 305 GRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQ 364
Query: 260 LKNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQ 312
+ LK E + E +LK+ SEE+ +R + SEN QP+
Sbjct: 365 M------------------LKISSENSNPEQDLKLTSEEESQRFKGSENSQPE 399
Score = 67.0 bits (162), Expect = 8e-11
Identities = 105/500 (21%), Positives = 186/500 (37%), Gaps = 71/500 (14%)
Query: 37 KIHRAAIKGDAAEVERC---LTRRFRDLDARDRKDRTVLHLACAHGRVQVVTLLLHRRCQ 93
K A IK + + C L D + D T LH A + + LL
Sbjct: 205 KKRTALIKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLHYAIYNEDKLMAKALLLYGAD 264
Query: 94 IDICDRLNRTPLMKAVHSQEEACAIVLLECGANPNIEDIYGNTALHYAVYNKGTSLAERL 153
I+ ++ TPL+ VH Q++ L++ AN N D YG TAL AV S+ L
Sbjct: 265 IESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVSLL 324
Query: 154 LSHHANIEALNKEGNTPLLFAINSRR----QHMVEFLLKNQANIHAVDNFKRTALILAVQ 209
L + ++ + + G T +A++S Q + ++ K I + ++ L L +
Sbjct: 325 LEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQMLKISSENSNPEQDLKLTSE 384
Query: 210 HNLSSIVTLLLQQNIRISSQ-------------DMFGQTAEDYALCSDLRS-------IR 249
Q ++S + +M + + L +L +
Sbjct: 385 EESQRFKGSENSQPEKMSQEPEINKDGDREVEEEMKKHESNNVGLLENLTNGVTAGNGDN 444
Query: 250 QQILEHKNKMLKNHLRNDNQETAAMKPANL----------KKRKERAKAEHNLKVASEEK 299
I + K++ +N DN+ + L K E + E +LK+ SEE+
Sbjct: 445 GLIPQRKSRTPENQQFPDNESEEYHRICELLSDYKEKQMPKYSSENSNPEQDLKLTSEEE 504
Query: 300 QERLQRSENKQPQ---DSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYI 356
+RL+ SEN QP+ K D NFM ++ + KK+
Sbjct: 505 SQRLKGSENGQPEKRSQEPEINKDGDRELENFM------------------AIEEMKKHR 546
Query: 357 QEIKSITEINANFEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLE 416
E N + ++ +I +R + EN +S+ + + + E
Sbjct: 547 STHVGFPENLTNGATAGNGDDGLIPPRKSRTPESQQFPDTENEEYHSDEQNDTQKQFCEE 606
Query: 417 AEVESLHSSLATAINEYNEIVERKDLELVLWRADDVSRHEKMGSNISQLTDKNELLTEQV 476
LH + + E+VE+ + EL L + EK + +N L E++
Sbjct: 607 QNTGILHDEILIHEEKQIEVVEKMNSELSL-----SCKKEK------DILHENSTLREEI 655
Query: 477 HKARVKFNTLK--GKLRETR 494
R++ +T+K +LRE +
Sbjct: 656 AMLRLELDTMKHQSQLREKK 675
Score = 58.9 bits (141), Expect = 2e-08
Identities = 39/128 (30%), Positives = 71/128 (55%), Gaps = 10/128 (7%)
Query: 250 QQILEHKNKMLKNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENK 309
QQ + +N+ + +ND Q+ ++ H+ + EEKQ ++ E
Sbjct: 581 QQFPDTENEEYHSDEQNDTQKQFC--------EEQNTGILHDEILIHEEKQ--IEVVEKM 630
Query: 310 QPQDSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANF 369
+ S S K+KD ++ N L+++IAML+ EL +K+ S +EKKY+++I+S+ + N N
Sbjct: 631 NSELSLSCKKEKDILHENSTLREEIAMLRLELDTMKHQSQLREKKYLEDIESVKKRNDNL 690
Query: 370 EKSVRLNE 377
K+++LNE
Sbjct: 691 LKALQLNE 698
>gi|113413200 PREDICTED: similar to protein expressed in prostate,
ovary, testis, and placenta 2 [Homo sapiens]
Length = 1038
Score = 238 bits (608), Expect = 2e-62
Identities = 130/293 (44%), Positives = 186/293 (63%), Gaps = 18/293 (6%)
Query: 20 DQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLDARDRKDRTVLHLACAHG 79
D + P Y +R +L K+HRAA G A + + R D++ +D++ RT LHLA A+G
Sbjct: 88 DSAFVEPRYHVRREDLDKLHRAAWWGKVARKDLIVMLRDTDVNKQDKQKRTALHLASANG 147
Query: 80 RVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLECGANPNIEDIYGNTALH 139
VV LLL RRCQ+++ D RT L KAV QE+ CA++LLE G +PNI D YGNT LH
Sbjct: 148 NSGVVKLLLDRRCQLNVLDNKKRTALTKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLH 207
Query: 140 YAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNF 199
YA+YN+ +A+ LL + A+IE+ NK G TPLL ++ ++Q +V+FL+K +AN++A+D +
Sbjct: 208 YAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRY 267
Query: 200 KRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQILEHKNKM 259
RTALILAV +SIV+LLL+QNI +SSQD+ GQTA +YA+ S I Q + ++K K
Sbjct: 268 GRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQ 327
Query: 260 LKNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQ 312
+ LK E + E +LK+ SEE+ +R + SEN QP+
Sbjct: 328 M------------------LKISSENSNPEQDLKLTSEEESQRFKGSENSQPE 362
Score = 62.8 bits (151), Expect = 2e-09
Identities = 100/496 (20%), Positives = 183/496 (36%), Gaps = 66/496 (13%)
Query: 29 DIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLDARDRKDRTVLHLACAHGRVQVVTLLL 88
++ D + R A++ E L D + D T LH A + + LL
Sbjct: 163 NVLDNKKRTALTKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLHYAIYNEDKLMAKALL 222
Query: 89 HRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLECGANPNIEDIYGNTALHYAVYNKGTS 148
I+ ++ TPL+ VH Q++ L++ AN N D YG TAL AV S
Sbjct: 223 LYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSAS 282
Query: 149 LAERLLSHHANIEALNKEGNTPLLFAINSRR----QHMVEFLLKNQANIHAVDNFKRTAL 204
+ LL + ++ + + G T +A++S Q + ++ K I + ++ L
Sbjct: 283 IVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQMLKISSENSNPEQDL 342
Query: 205 ILAVQHNLSSIVTLLLQQNIRISSQ-------------DMFGQTAEDYALCSDLRSIRQQ 251
L + Q ++S + +M + + L +L +
Sbjct: 343 KLTSEEESQRFKGSENSQPEKMSQEPEINKDGDREVEEEMKKHESNNVGLLENLSNGVTA 402
Query: 252 -------ILEHKNKMLKNHLRNDNQETAAMKPANL----------KKRKERAKAEHNLKV 294
I + K++ +N DN+ + L K E + E +LK+
Sbjct: 403 GNGDDGLIPQRKSRTPENQQFPDNESEEYHRICELVSDYKEKQMPKYSSENSNPEQDLKL 462
Query: 295 ASEEKQERLQRSENKQPQ---DSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRK 351
SEE+ +RL+ SEN QP+ K D NFM ++ +
Sbjct: 463 TSEEESQRLKGSENGQPEKRSQEPEINKDGDRELENFM------------------AIEE 504
Query: 352 EKKYIQEIKSITEINANFEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHN 411
KK+ E N + ++ +I +R + EN +S+ + +
Sbjct: 505 MKKHGSTHVGFPENLTNGATAGNGDDGLIPPRKSRTPESQQFPDTENEEYHSDEQNDTQK 564
Query: 412 KERLEAEVESLHSSLATAINEYNEIVERKDLELVLWRADDVSRHEKMGSNISQLTDKNEL 471
+ E LH + + E+VE+ + EL L + E+ +N +
Sbjct: 565 QFCEEQNTGILHDEILIHEEKQIEVVEKMNSELSL-----SCKKER------DFLHENSM 613
Query: 472 LTEQVHKARVKFNTLK 487
L E++ R++ +T+K
Sbjct: 614 LREEIAMLRLELDTMK 629
Score = 58.2 bits (139), Expect = 4e-08
Identities = 38/128 (29%), Positives = 72/128 (56%), Gaps = 10/128 (7%)
Query: 250 QQILEHKNKMLKNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENK 309
QQ + +N+ + +ND Q+ ++ H+ + EEKQ ++ E
Sbjct: 544 QQFPDTENEEYHSDEQNDTQKQFC--------EEQNTGILHDEILIHEEKQ--IEVVEKM 593
Query: 310 QPQDSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANF 369
+ S S K++D ++ N ML+++IAML+ EL +K+ S ++KKY+++I+S+ + N N
Sbjct: 594 NSELSLSCKKERDFLHENSMLREEIAMLRLELDTMKHQSQLRKKKYLEDIESVKKKNDNL 653
Query: 370 EKSVRLNE 377
K+++LNE
Sbjct: 654 LKALQLNE 661
>gi|88953571 PREDICTED: similar to protein expressed in prostate,
ovary, testis, and placenta 2 isoform 2 [Homo sapiens]
Length = 1075
Score = 238 bits (608), Expect = 2e-62
Identities = 130/293 (44%), Positives = 186/293 (63%), Gaps = 18/293 (6%)
Query: 20 DQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLDARDRKDRTVLHLACAHG 79
D + P Y +R +L K+HRAA G A + + R D++ +D++ RT LHLA A+G
Sbjct: 125 DSAFVEPRYHVRREDLDKLHRAAWWGKVARKDLIVMLRDTDVNKQDKQKRTALHLASANG 184
Query: 80 RVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLECGANPNIEDIYGNTALH 139
VV LLL RRCQ+++ D RT L KAV QE+ CA++LLE G +PNI D YGNT LH
Sbjct: 185 NSGVVKLLLDRRCQLNVLDNKKRTALTKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLH 244
Query: 140 YAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNF 199
YA+YN+ +A+ LL + A+IE+ NK G TPLL ++ ++Q +V+FL+K +AN++A+D +
Sbjct: 245 YAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRY 304
Query: 200 KRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQILEHKNKM 259
RTALILAV +SIV+LLL+QNI +SSQD+ GQTA +YA+ S I Q + ++K K
Sbjct: 305 GRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQ 364
Query: 260 LKNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQ 312
+ LK E + E +LK+ SEE+ +R + SEN QP+
Sbjct: 365 M------------------LKISSENSNPEQDLKLTSEEESQRFKGSENSQPE 399
Score = 62.8 bits (151), Expect = 2e-09
Identities = 101/496 (20%), Positives = 182/496 (36%), Gaps = 66/496 (13%)
Query: 29 DIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLDARDRKDRTVLHLACAHGRVQVVTLLL 88
++ D + R A++ E L D + D T LH A + + LL
Sbjct: 200 NVLDNKKRTALTKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLHYAIYNEDKLMAKALL 259
Query: 89 HRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLECGANPNIEDIYGNTALHYAVYNKGTS 148
I+ ++ TPL+ VH Q++ L++ AN N D YG TAL AV S
Sbjct: 260 LYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSAS 319
Query: 149 LAERLLSHHANIEALNKEGNTPLLFAINSRR----QHMVEFLLKNQANIHAVDNFKRTAL 204
+ LL + ++ + + G T +A++S Q + ++ K I + ++ L
Sbjct: 320 IVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQMLKISSENSNPEQDL 379
Query: 205 ILAVQHNLSSIVTLLLQQNIRISSQ-------------DMFGQTAEDYALCSDLRSIRQQ 251
L + Q ++S + +M + + L +L +
Sbjct: 380 KLTSEEESQRFKGSENSQPEKMSQEPEINKDGDREVEEEMKKHESNNVGLLENLSNGVTA 439
Query: 252 -------ILEHKNKMLKNHLRNDNQETAAMKPANL----------KKRKERAKAEHNLKV 294
I + K++ +N DN+ + L K E + E +LK+
Sbjct: 440 GNGDDGLIPQRKSRTPENQQFPDNESEEYHRICELVSDYKEKQMPKYSSENSNPEQDLKL 499
Query: 295 ASEEKQERLQRSENKQPQ---DSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRK 351
SEE+ +RL+ SEN QP+ K D NFM ++ +
Sbjct: 500 TSEEESQRLKGSENGQPEKRSQEPEINKDGDRELENFM------------------AIEE 541
Query: 352 EKKYIQEIKSITEINANFEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHN 411
KK+ E N + ++ +I +R + EN +S+ + +
Sbjct: 542 MKKHGSTHVGFPENLTNGATAGNGDDGLIPPRKSRTPESQQFPDTENEEYHSDEQNDTQK 601
Query: 412 KERLEAEVESLHSSLATAINEYNEIVERKDLELVLWRADDVSRHEKMGSNISQLTDKNEL 471
+ E LH + + E+VE+ + EL L + EK +N
Sbjct: 602 QFCEEQNTGILHDEILIHEEKQIEVVEKMNSELSL-----SCKKEK------DFLHENST 650
Query: 472 LTEQVHKARVKFNTLK 487
L E++ R++ +T+K
Sbjct: 651 LREEIAMLRLELDTMK 666
Score = 57.0 bits (136), Expect = 9e-08
Identities = 38/128 (29%), Positives = 71/128 (55%), Gaps = 10/128 (7%)
Query: 250 QQILEHKNKMLKNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENK 309
QQ + +N+ + +ND Q+ ++ H+ + EEKQ ++ E
Sbjct: 581 QQFPDTENEEYHSDEQNDTQKQFC--------EEQNTGILHDEILIHEEKQ--IEVVEKM 630
Query: 310 QPQDSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANF 369
+ S S K+KD ++ N L+++IAML+ EL +K+ S ++KKY+++I+S+ + N N
Sbjct: 631 NSELSLSCKKEKDFLHENSTLREEIAMLRLELDTMKHQSQLRKKKYLEDIESVKKKNDNL 690
Query: 370 EKSVRLNE 377
K+++LNE
Sbjct: 691 LKALQLNE 698
>gi|153792284 pote protein [Homo sapiens]
Length = 584
Score = 235 bits (600), Expect = 1e-61
Identities = 164/490 (33%), Positives = 259/490 (52%), Gaps = 69/490 (14%)
Query: 26 PGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLDARDRKDRTVLHLACAHGRVQVVT 85
P Y IR +L K+HRAA G + + R D++ RD++ RT LHLA A+G +VV
Sbjct: 131 PRYHIRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKEKRTALHLASANGNSEVVQ 190
Query: 86 LLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLECGANPNIEDIYGNTALHYAVYNK 145
LLL RRCQ+++ D RT L+KA+ QE+ C ++LLE GA+ NI D YGNTALHYA+YN+
Sbjct: 191 LLLDRRCQLNVLDNKKRTALIKAIQCQEDECVLMLLEHGADRNIPDEYGNTALHYAIYNE 250
Query: 146 GTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNFKRTALI 205
+A+ LL + A+IE+ NK G TPLL ++ ++Q +V+FL+K +AN++ +D + RTALI
Sbjct: 251 DKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQQVVKFLIKKKANLNVLDRYGRTALI 310
Query: 206 LAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQILEHKNKMLKNHLR 265
LAV +SIV LLL+QN+ +SSQD+ GQTA +YA+ S I + + ++K K +
Sbjct: 311 LAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDYKEKQM----- 365
Query: 266 NDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQDSQSYGKKKDAMY 325
LK E + E +LK+ SEE+ +RL+ SEN QP+ +
Sbjct: 366 -------------LKISSENSNPEQDLKLTSEEESQRLKVSENSQPEKMSQEPE------ 406
Query: 326 GNFMLKKDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEKMITKTVA 385
+ KD EE + KK+ + E N + ++ +I + +
Sbjct: 407 ----INKDCDREVEE----------EIKKHGSNPVGLPENLTNGASAGNGDDGLIPQRRS 452
Query: 386 RYSQQLNDLKAENARLNSELEKEKHNKERLEAEVESLHSSLATAINEYNEIVERKDLELV 445
R K EN + +E H+ E+ + + L T I++ +EI+ K ++
Sbjct: 453 R--------KPENQQFPDTENEEYHSDEQNDTR-KQLSEEQNTGISQ-DEILTNKQKQIE 502
Query: 446 LWRADDVSRHEKMGSNIS-------QLTDKNELLTEQVHKARVKFNTLK-------GKLR 491
+ +KM S +S L +N +L E++ R++ + K K+
Sbjct: 503 V-------AEQKMNSELSLSHKKEEDLLRENSVLQEEIAMLRLELDETKHQNQLRENKIL 555
Query: 492 ETRDALREKT 501
E ++++EKT
Sbjct: 556 EEIESVKEKT 565
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.129 0.352
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,258,801
Number of Sequences: 37866
Number of extensions: 1568642
Number of successful extensions: 19519
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 562
Number of HSP's successfully gapped in prelim test: 1147
Number of HSP's that attempted gapping in prelim test: 7508
Number of HSP's gapped (non-prelim): 6739
length of query: 1002
length of database: 18,247,518
effective HSP length: 112
effective length of query: 890
effective length of database: 14,006,526
effective search space: 12465808140
effective search space used: 12465808140
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.