Guide to the Human Genome
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Search of human proteins with 117938254

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|117938254 BCL2-associated transcription factor 1 isoform 3
[Homo sapiens]
         (747 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|117938254 BCL2-associated transcription factor 1 isoform 3 [H...  1513   0.0  
gi|7661958 BCL2-associated transcription factor 1 isoform 1 [Hom...   838   0.0  
gi|117938251 BCL2-associated transcription factor 1 isoform 2 [H...   677   0.0  
gi|169218320 PREDICTED: similar to BCL2-associated transcription...   675   0.0  
gi|239756568 PREDICTED: similar to BCL2-associated transcription...   664   0.0  
gi|167234419 thyroid hormone receptor associated protein 3 [Homo...   367   e-101
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]       109   8e-24
gi|115511057 hypothetical protein LOC256643 [Homo sapiens]            103   4e-22
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]          96   9e-20
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]     94   6e-19
gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sap...    89   1e-17
gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sap...    89   1e-17
gi|133922600 splicing factor, arginine/serine-rich 16 [Homo sapi...    89   2e-17
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ...    86   2e-16
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [...    86   2e-16
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]     81   4e-15
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         80   5e-15
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]           80   9e-15
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]           80   9e-15
gi|15055543 splicing factor, arginine/serine-rich 2B [Homo sapiens]    79   1e-14
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi...    79   2e-14
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ...    76   1e-13
gi|42560244 peptidylprolyl isomerase G [Homo sapiens]                  76   1e-13
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    76   1e-13
gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo s...    73   8e-13
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s...    73   8e-13
gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens]      73   1e-12
gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]           72   2e-12
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]    71   3e-12
gi|126723149 chromosome 19 open reading frame 29 [Homo sapiens]        71   4e-12

>gi|117938254 BCL2-associated transcription factor 1 isoform 3 [Homo
           sapiens]
          Length = 747

 Score = 1513 bits (3916), Expect = 0.0
 Identities = 747/747 (100%), Positives = 747/747 (100%)

Query: 1   MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD 60
           MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD
Sbjct: 1   MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD 60

Query: 61  YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 120
           YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV
Sbjct: 61  YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 120

Query: 121 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK 180
           SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK
Sbjct: 121 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK 180

Query: 181 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS 240
           SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS
Sbjct: 181 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS 240

Query: 241 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS 300
           SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS
Sbjct: 241 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS 300

Query: 301 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKSPPLHKNLDAREKSTFREESPL 360
           PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKSPPLHKNLDAREKSTFREESPL
Sbjct: 301 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKSPPLHKNLDAREKSTFREESPL 360

Query: 361 RIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIK 420
           RIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIK
Sbjct: 361 RIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIK 420

Query: 421 LPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHR 480
           LPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHR
Sbjct: 421 LPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHR 480

Query: 481 RIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKG 540
           RIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKG
Sbjct: 481 RIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKG 540

Query: 541 SRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKER 600
           SRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKER
Sbjct: 541 SRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKER 600

Query: 601 EEEFKTHHEMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEE 660
           EEEFKTHHEMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEE
Sbjct: 601 EEEFKTHHEMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEE 660

Query: 661 EWDPEYTPKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQ 720
           EWDPEYTPKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQ
Sbjct: 661 EWDPEYTPKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQ 720

Query: 721 GDGIVEDEEETMENNEEKKDRRKEEKE 747
           GDGIVEDEEETMENNEEKKDRRKEEKE
Sbjct: 721 GDGIVEDEEETMENNEEKKDRRKEEKE 747


>gi|7661958 BCL2-associated transcription factor 1 isoform 1 [Homo
           sapiens]
          Length = 920

 Score =  838 bits (2165), Expect = 0.0
 Identities = 467/740 (63%), Positives = 515/740 (69%), Gaps = 61/740 (8%)

Query: 13  SKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNNRGMRRPYG 72
           S+S S S +   S  HS K   S  S S  +S  RS                        
Sbjct: 237 SQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERS------------------------ 272

Query: 73  YRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRS 132
               G G    G  RY      P+ +    RSP +  +   +P        R  SR R S
Sbjct: 273 ----GSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAP--------RDESRGRSS 320

Query: 133 YRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAE-GEPQEESPLKSKSQEEPKDTF 191
           +      + ++             KR   +E +    + G  +++   K K  E+ +   
Sbjct: 321 FYPDGGDQETAKTGK-------FLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEG 373

Query: 192 EHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTV 251
           E +  E++D F+   +       G   +++S       +       +S         +T 
Sbjct: 374 EWEDQEALDYFSDKES-------GKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATA 426

Query: 252 HSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAP 311
            S +NT  +    +++  + S  G+    S  +   +N  +           T   ++  
Sbjct: 427 -SHRNTEEE---GLKYKSKVSLKGN--RESDGFREEKNYKLKETGYVVERPSTTKDKHKE 480

Query: 312 RDESRGRSSFYPDGGDQETAKTGK----FLKSPPLHKNLDAREKSTFREESPLRIKMIAS 367
            D++  R +   +    E  K+ K    F  SPPLHKNLDAREKSTFREESPLRIKMIAS
Sbjct: 481 EDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIAS 540

Query: 368 DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS 427
           DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS
Sbjct: 541 DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS 600

Query: 428 TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS 487
           TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS
Sbjct: 601 TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS 660

Query: 488 TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS 547
           TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS
Sbjct: 661 TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS 720

Query: 548 RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH 607
           RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH
Sbjct: 721 RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH 780

Query: 608 HEMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYT 667
           HEMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYT
Sbjct: 781 HEMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYT 840

Query: 668 PKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVED 727
           PKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVED
Sbjct: 841 PKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVED 900

Query: 728 EEETMENNEEKKDRRKEEKE 747
           EEETMENNEEKKDRRKEEKE
Sbjct: 901 EEETMENNEEKKDRRKEEKE 920



 Score =  686 bits (1769), Expect = 0.0
 Identities = 338/338 (100%), Positives = 338/338 (100%)

Query: 1   MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD 60
           MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD
Sbjct: 1   MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD 60

Query: 61  YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 120
           YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV
Sbjct: 61  YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 120

Query: 121 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK 180
           SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK
Sbjct: 121 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK 180

Query: 181 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS 240
           SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS
Sbjct: 181 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS 240

Query: 241 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS 300
           SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS
Sbjct: 241 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS 300

Query: 301 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLK 338
           PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLK
Sbjct: 301 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLK 338



 Score = 38.1 bits (87), Expect = 0.030
 Identities = 42/197 (21%), Positives = 75/197 (38%), Gaps = 26/197 (13%)

Query: 564 KDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFK---------THHEMKEYS 614
           + +S+    +  SRS SSS S S   SR+++ S + R   +          +    ++Y 
Sbjct: 3   RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYR 62

Query: 615 GFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEY--TPKSKK 672
              G+ RP G       RGR RG + G           + +      W+  +  +P+  +
Sbjct: 63  NNRGMRRPYGY------RGRGRGYYQG-------GGGRYHRGGYRPVWNRRHSRSPRRGR 109

Query: 673 YFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSP--KWTHDKYQGDGIVEDEEE 730
                 +   V     R R R +++  R   +     SSP  K    K +G    + ++ 
Sbjct: 110 SRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKA 169

Query: 731 TMENNEEKKDRRKEEKE 747
             E  EE   + K ++E
Sbjct: 170 EGEPQEESPLKSKSQEE 186



 Score = 38.1 bits (87), Expect = 0.030
 Identities = 42/197 (21%), Positives = 75/197 (38%), Gaps = 26/197 (13%)

Query: 3   RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYR 62
           + +S+    +  SRS SSS S S   SR+++ S + R   +          +    ++Y 
Sbjct: 737 KDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFK---------THHEMKEYS 787

Query: 63  NNRGMRRPYGY------RGRGRGYYQG-------GGGRYHRGGYRPVWNRRHSRSPRRGR 109
              G+ RP G       RGR RG + G           + +      W+  +  +P+  +
Sbjct: 788 GFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEY--TPKSKK 845

Query: 110 SRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKA 169
                 +   V     R R R +++  R   +     SSP  K    K +G    + ++ 
Sbjct: 846 YFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSP--KWTHDKYQGDGIVEDEEE 903

Query: 170 EGEPQEESPLKSKSQEE 186
             E  EE   + K ++E
Sbjct: 904 TMENNEEKKDRRKEEKE 920



 Score = 33.1 bits (74), Expect = 0.97
 Identities = 43/187 (22%), Positives = 78/187 (41%), Gaps = 25/187 (13%)

Query: 460 TSYQKATEEHSTRQKSPEIHRRIDISP-STLRKHTRLAGEERVFKEENQKGDKKLRCDSA 518
           +S  K+  + S+R +S    R+   S  S  R ++R    +R++  + ++  +  R    
Sbjct: 10  SSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNNR---- 65

Query: 519 DLRHDIDRRRKERSKERG--------------DSKGSRESSGSRKQEKTPKDYKEYKSYK 564
            +R     R + R   +G              + + SR     R + ++PK  +   S +
Sbjct: 66  GMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKR-RSVSSQR 124

Query: 565 DDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKT---HHEMKEYSGFAGVSR 621
             S+ +R    SRS  SS+S SS    +   SK+   +E +T     E +E S     S+
Sbjct: 125 SRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQ 184

Query: 622 --PRGTF 626
             P+ TF
Sbjct: 185 EEPKDTF 191



 Score = 33.1 bits (74), Expect = 0.97
 Identities = 43/187 (22%), Positives = 78/187 (41%), Gaps = 25/187 (13%)

Query: 10  SSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNNR---- 65
           +S  K+  + S+R +S    R+   S  S  R ++R    +R++  + ++  +  R    
Sbjct: 633 TSYQKATEEHSTRQKSPEIHRRIDISP-STLRKHTRLAGEERVFKEENQKGDKKLRCDSA 691

Query: 66  GMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKR-RSVSSQR 124
            +R     R + R   +G              + + SR     R + ++PK  +   S +
Sbjct: 692 DLRHDIDRRRKERSKERG--------------DSKGSRESSGSRKQEKTPKDYKEYKSYK 737

Query: 125 SRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQ 184
             S+ +R    SRS  SS+S SS    +   SK+   +E +T     E +E S     S+
Sbjct: 738 DDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKT---HHEMKEYSGFAGVSR 794

Query: 185 EEPKDTF 191
             P+ TF
Sbjct: 795 --PRGTF 799


>gi|117938251 BCL2-associated transcription factor 1 isoform 2 [Homo
           sapiens]
          Length = 869

 Score =  677 bits (1748), Expect = 0.0
 Identities = 336/338 (99%), Positives = 336/338 (99%), Gaps = 2/338 (0%)

Query: 1   MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD 60
           MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRY  RSRSRTYSRSRSRDRMYSRDYRRD
Sbjct: 1   MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRY--RSRSRTYSRSRSRDRMYSRDYRRD 58

Query: 61  YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 120
           YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV
Sbjct: 59  YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 118

Query: 121 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK 180
           SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK
Sbjct: 119 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK 178

Query: 181 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS 240
           SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS
Sbjct: 179 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS 238

Query: 241 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS 300
           SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS
Sbjct: 239 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS 298

Query: 301 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLK 338
           PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLK
Sbjct: 299 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLK 336



 Score =  659 bits (1700), Expect = 0.0
 Identities = 403/748 (53%), Positives = 452/748 (60%), Gaps = 126/748 (16%)

Query: 13  SKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNNRGMRRPYG 72
           S+S S S +   S  HS K   S  S S  +S  RS                        
Sbjct: 235 SQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERS------------------------ 270

Query: 73  YRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRS 132
               G G    G  RY      P+ +    RSP +  +   +P        R  SR R S
Sbjct: 271 ----GSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAP--------RDESRGRSS 318

Query: 133 YRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAE-GEPQEESPLKSKSQEEPKDTF 191
           +      + ++             KR   +E +    + G  +++   K K  E+ +   
Sbjct: 319 FYPDGGDQETAKTGK-------FLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEG 371

Query: 192 EHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTV 251
           E +  E++D F+   +       G   +++S       +       +S         +T 
Sbjct: 372 EWEDQEALDYFSDKES-------GKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATA 424

Query: 252 HSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAP 311
            S +NT  +    +++  + S  G+    S  +   +N  +           T   ++  
Sbjct: 425 -SHRNTEEE---GLKYKSKVSLKGN--RESDGFREEKNYKLKETGYVVERPSTTKDKHKE 478

Query: 312 RDESRGRSSFYPDGGDQETAKTGK----FLKSPPLHKNLDAREKSTFREESPLRIKMIAS 367
            D++  R +   +    E  K+ K    F  SPPLHKNLDAREKSTFREESPLRIKMIAS
Sbjct: 479 EDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIAS 538

Query: 368 DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS 427
           DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS
Sbjct: 539 DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS 598

Query: 428 TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS 487
           TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS
Sbjct: 599 TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS 658

Query: 488 TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS 547
           TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS
Sbjct: 659 TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS 718

Query: 548 RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH 607
           RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH
Sbjct: 719 RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH 778

Query: 608 HEMKEYSGFAGVSRPRGTFFRIRG--------RGRARGVFAGTNTGPNNSNTTFQKRPKE 659
           HEMKEYSGFAGVSRPRGTF   R         RGR RG F                    
Sbjct: 779 HEMKEYSGFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTF-------------------- 818

Query: 660 EEWDPEYTPKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKY 719
                                       +RGR         GRFNFKKSGSSPKWTHDKY
Sbjct: 819 ----------------------------QRGR---------GRFNFKKSGSSPKWTHDKY 841

Query: 720 QGDGIVEDEEETMENNEEKKDRRKEEKE 747
           QGDGIVEDEEETMENNEEKKDRRKEEKE
Sbjct: 842 QGDGIVEDEEETMENNEEKKDRRKEEKE 869



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 31/111 (27%), Positives = 48/111 (43%), Gaps = 25/111 (22%)

Query: 3   RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYR 62
           + +S+    +  SRS SSS S S   SR+++ S + R   +          +    ++Y 
Sbjct: 735 KDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFK---------THHEMKEYS 785

Query: 63  NNRGMRRPYG--------------YRGRGRGYYQGGGGRYH--RGGYRPVW 97
              G+ RP G               RGRGRG +Q G GR++  + G  P W
Sbjct: 786 GFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKW 836



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 52/225 (23%), Positives = 92/225 (40%), Gaps = 26/225 (11%)

Query: 10  SSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNNR---- 65
           +S  K+  + S+R +S    R+   S  S  R ++R    +R++  + ++  +  R    
Sbjct: 631 TSYQKATEEHSTRQKSPEIHRRIDISP-STLRKHTRLAGEERVFKEENQKGDKKLRCDSA 689

Query: 66  GMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKR-RSVSSQR 124
            +R     R + R   +G              + + SR     R + ++PK  +   S +
Sbjct: 690 DLRHDIDRRRKERSKERG--------------DSKGSRESSGSRKQEKTPKDYKEYKSYK 735

Query: 125 SRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQ 184
             S+ +R    SRS  SS+S SS    +   SK+   +E +T     E +E S     S+
Sbjct: 736 DDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKT---HHEMKEYSGFAGVSR 792

Query: 185 EEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSP 229
             P+ TF  D  + +D + K     G    G   + N  +S  SP
Sbjct: 793 --PRGTFHDDRDDGVDYWAKRGRGRGTFQRGRGRF-NFKKSGSSP 834



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 41/195 (21%), Positives = 74/195 (37%), Gaps = 24/195 (12%)

Query: 564 KDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKER-------EEEFKTHHEMKEYSGF 616
           + +S+    +  SRS SSS S S   SR+++   + R        +   +    ++Y   
Sbjct: 3   RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNN 62

Query: 617 AGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEY--TPKSKKYF 674
            G+ RP G       RGR RG + G           + +      W+  +  +P+  +  
Sbjct: 63  RGMRRPYGY------RGRGRGYYQG-------GGGRYHRGGYRPVWNRRHSRSPRRGRSR 109

Query: 675 LHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSP--KWTHDKYQGDGIVEDEEETM 732
               +   V     R R R +++  R   +     SSP  K    K +G    + ++   
Sbjct: 110 SRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEG 169

Query: 733 ENNEEKKDRRKEEKE 747
           E  EE   + K ++E
Sbjct: 170 EPQEESPLKSKSQEE 184



 Score = 33.5 bits (75), Expect = 0.74
 Identities = 43/186 (23%), Positives = 77/186 (41%), Gaps = 25/186 (13%)

Query: 460 TSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSAD 519
           +S  K+  + S+R +S   H R     S  R ++R    +R++  + ++  +  R     
Sbjct: 10  SSRSKSRSQSSSRSRSRS-HSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNNR----G 64

Query: 520 LRHDIDRRRKERSKERG--------------DSKGSRESSGSRKQEKTPKDYKEYKSYKD 565
           +R     R + R   +G              + + SR     R + ++PK  +   S + 
Sbjct: 65  MRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKR-RSVSSQRS 123

Query: 566 DSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKT---HHEMKEYSGFAGVSR- 621
            S+ +R    SRS  SS+S SS    +   SK+   +E +T     E +E S     S+ 
Sbjct: 124 RSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQE 183

Query: 622 -PRGTF 626
            P+ TF
Sbjct: 184 EPKDTF 189



 Score = 30.4 bits (67), Expect = 6.3
 Identities = 25/99 (25%), Positives = 41/99 (41%), Gaps = 20/99 (20%)

Query: 631 GRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYTPKSKKYFLHDDRDD--GVDY--- 685
           GR  +R   + ++   + S ++ + R +       Y  +S+ Y     RD     DY   
Sbjct: 2   GRSNSR---SHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRD 58

Query: 686 ----------WAKRGRGRGTFQRGRGRFNFKKSGSSPKW 714
                     +  RGRGRG +Q G GR++  + G  P W
Sbjct: 59  YRNNRGMRRPYGYRGRGRGYYQGGGGRYH--RGGYRPVW 95


>gi|169218320 PREDICTED: similar to BCL2-associated transcription
           factor 1 isoform 2 [Homo sapiens]
          Length = 869

 Score =  675 bits (1742), Expect = 0.0
 Identities = 335/338 (99%), Positives = 335/338 (99%), Gaps = 2/338 (0%)

Query: 1   MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD 60
           MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRY  RSRSRTYSRSRSRDRMYSRDYRRD
Sbjct: 1   MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRY--RSRSRTYSRSRSRDRMYSRDYRRD 58

Query: 61  YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 120
           YRNNR MRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV
Sbjct: 59  YRNNRAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 118

Query: 121 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK 180
           SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK
Sbjct: 119 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK 178

Query: 181 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS 240
           SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS
Sbjct: 179 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS 238

Query: 241 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS 300
           SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS
Sbjct: 239 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS 298

Query: 301 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLK 338
           PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLK
Sbjct: 299 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLK 336



 Score =  643 bits (1658), Expect = 0.0
 Identities = 397/749 (53%), Positives = 449/749 (59%), Gaps = 128/749 (17%)

Query: 13  SKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNNRGMRRPYG 72
           S+S S S +   S  HS K   S  S S  +S  RS                        
Sbjct: 235 SQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERS------------------------ 270

Query: 73  YRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRS 132
               G G    G  RY      P+ +    RSP +  +   +P        R  SR R S
Sbjct: 271 ----GSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAP--------RDESRGRSS 318

Query: 133 YRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAE-GEPQEESPLKSKSQEEPKDTF 191
           +      + ++             KR   +E +    + G  +++   K K  E+ +   
Sbjct: 319 FYPDGGDQETAKTGK-------FLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEG 371

Query: 192 EHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTV 251
           E +  E++D F+   +       G   +++S       +       +S         +T 
Sbjct: 372 EWEDQEALDYFSDKES-------GKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATA 424

Query: 252 HSAKNTPSQHSHSIQHSPERSGSGS-VGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNA 310
            S +NT  +    +++  + S  G+   +G       ++    ++  R S  K    ++ 
Sbjct: 425 -SHRNTEEE---GLKYKSKVSLKGNRESDGFREEKNDKHKETGYVVERPSTTKD---KHK 477

Query: 311 PRDESRGRSSFYPDGGDQETAKTGK----FLKSPPLHKNLDAREKSTFREESPLRIKMIA 366
             D++  R +   +    E  K+ K    F  SPPLHKNLDAREKSTFREESPLRIKMIA
Sbjct: 478 EEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIA 537

Query: 367 SDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASK 426
           SDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASK
Sbjct: 538 SDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASK 597

Query: 427 STSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISP 486
           STSESFIQHIVSLVHHVKEQYFKSAAMTL+ERFTSYQKATEEHSTRQKSPEIHRRIDISP
Sbjct: 598 STSESFIQHIVSLVHHVKEQYFKSAAMTLSERFTSYQKATEEHSTRQKSPEIHRRIDISP 657

Query: 487 STLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSG 546
           STLRK TRLAGEERVFKEENQKGDKKLRCDSADLRHDID RRKERSKERGDSKGSRES G
Sbjct: 658 STLRKDTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDHRRKERSKERGDSKGSRESRG 717

Query: 547 SRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKT 606
           SRKQEKTPKDYKEYKSYKDDSKHKREQDHS SSSSSASPSSPSSREEKESKKEREEEFKT
Sbjct: 718 SRKQEKTPKDYKEYKSYKDDSKHKREQDHSLSSSSSASPSSPSSREEKESKKEREEEFKT 777

Query: 607 HHEMKEYSGFAGVSRPRGTFFRIRG--------RGRARGVFAGTNTGPNNSNTTFQKRPK 658
           HHEMKEYSGFAGVSRPRGTF   R         RGR RG F                   
Sbjct: 778 HHEMKEYSGFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTF------------------- 818

Query: 659 EEEWDPEYTPKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDK 718
                                        +RGR         GRFNFKKSGSSPKW HDK
Sbjct: 819 -----------------------------QRGR---------GRFNFKKSGSSPKWNHDK 840

Query: 719 YQGDGIVEDEEETMENNEEKKDRRKEEKE 747
           YQGDGIVEDEEETMENNEEKKDR KEEKE
Sbjct: 841 YQGDGIVEDEEETMENNEEKKDRCKEEKE 869



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 31/112 (27%), Positives = 47/112 (41%), Gaps = 25/112 (22%)

Query: 3   RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYR 62
           + +S+    +  S S SSS S S   SR+++ S + R   +               ++Y 
Sbjct: 735 KDDSKHKREQDHSLSSSSSASPSSPSSREEKESKKEREEEFKTHHEM---------KEYS 785

Query: 63  NNRGMRRPYGY--------------RGRGRGYYQGGGGRYH--RGGYRPVWN 98
              G+ RP G               RGRGRG +Q G GR++  + G  P WN
Sbjct: 786 GFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWN 837



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 53/230 (23%), Positives = 95/230 (41%), Gaps = 28/230 (12%)

Query: 6   SRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNNR 65
           S   +S  K+  + S+R +S    R+   S  S  R  +R    +R++  + ++  +  R
Sbjct: 627 SERFTSYQKATEEHSTRQKSPEIHRRIDISP-STLRKDTRLAGEERVFKEENQKGDKKLR 685

Query: 66  ----GMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKR-RSV 120
                +R    +R + R   +G              + + SR  R  R + ++PK  +  
Sbjct: 686 CDSADLRHDIDHRRKERSKERG--------------DSKGSRESRGSRKQEKTPKDYKEY 731

Query: 121 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTK-KAEGEPQEESPL 179
            S +  S+ +R    S S    SS S+SP S S   ++   +E++ + K   E +E S  
Sbjct: 732 KSYKDDSKHKREQDHSLS----SSSSASPSSPSSREEKESKKEREEEFKTHHEMKEYSGF 787

Query: 180 KSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSP 229
              S+  P+ TF  D  + +D + K     G    G   + N  +S  SP
Sbjct: 788 AGVSR--PRGTFHDDRDDGVDYWAKRGRGRGTFQRGRGRF-NFKKSGSSP 834



 Score = 33.9 bits (76), Expect = 0.57
 Identities = 40/195 (20%), Positives = 73/195 (37%), Gaps = 24/195 (12%)

Query: 564 KDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKER-------EEEFKTHHEMKEYSGF 616
           + +S+    +  SRS SSS S S   SR+++   + R        +   +    ++Y   
Sbjct: 3   RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNN 62

Query: 617 AGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEY--TPKSKKYF 674
             + RP G       RGR RG + G           + +      W+  +  +P+  +  
Sbjct: 63  RAMRRPYGY------RGRGRGYYQG-------GGGRYHRGGYRPVWNRRHSRSPRRGRSR 109

Query: 675 LHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSP--KWTHDKYQGDGIVEDEEETM 732
               +   V     R R R +++  R   +     SSP  K    K +G    + ++   
Sbjct: 110 SRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEG 169

Query: 733 ENNEEKKDRRKEEKE 747
           E  EE   + K ++E
Sbjct: 170 EPQEESPLKSKSQEE 184



 Score = 33.9 bits (76), Expect = 0.57
 Identities = 43/186 (23%), Positives = 77/186 (41%), Gaps = 25/186 (13%)

Query: 460 TSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSAD 519
           +S  K+  + S+R +S   H R     S  R ++R    +R++  + ++  +  R     
Sbjct: 10  SSRSKSRSQSSSRSRSRS-HSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNNRA---- 64

Query: 520 LRHDIDRRRKERSKERG--------------DSKGSRESSGSRKQEKTPKDYKEYKSYKD 565
           +R     R + R   +G              + + SR     R + ++PK  +   S + 
Sbjct: 65  MRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKR-RSVSSQRS 123

Query: 566 DSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKT---HHEMKEYSGFAGVSR- 621
            S+ +R    SRS  SS+S SS    +   SK+   +E +T     E +E S     S+ 
Sbjct: 124 RSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQE 183

Query: 622 -PRGTF 626
            P+ TF
Sbjct: 184 EPKDTF 189



 Score = 30.4 bits (67), Expect = 6.3
 Identities = 25/99 (25%), Positives = 41/99 (41%), Gaps = 20/99 (20%)

Query: 631 GRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYTPKSKKYFLHDDRDD--GVDY--- 685
           GR  +R   + ++   + S ++ + R +       Y  +S+ Y     RD     DY   
Sbjct: 2   GRSNSR---SHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRD 58

Query: 686 ----------WAKRGRGRGTFQRGRGRFNFKKSGSSPKW 714
                     +  RGRGRG +Q G GR++  + G  P W
Sbjct: 59  YRNNRAMRRPYGYRGRGRGYYQGGGGRYH--RGGYRPVW 95


>gi|239756568 PREDICTED: similar to BCL2-associated transcription
           factor 1 [Homo sapiens]
          Length = 869

 Score =  664 bits (1712), Expect = 0.0
 Identities = 331/338 (97%), Positives = 331/338 (97%), Gaps = 2/338 (0%)

Query: 1   MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD 60
           MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRY  RSRSRTYSRSRSRDRMYSRDYRRD
Sbjct: 1   MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRY--RSRSRTYSRSRSRDRMYSRDYRRD 58

Query: 61  YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 120
           YRNNR MRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV
Sbjct: 59  YRNNRAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 118

Query: 121 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK 180
           SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGE QEESPLK
Sbjct: 119 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGELQEESPLK 178

Query: 181 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS 240
           SKSQEEPKDTFEHD SESIDEFNKSSAT GDIWPGLSAYD SPRSPHSPSPIATPPSQSS
Sbjct: 179 SKSQEEPKDTFEHDSSESIDEFNKSSATCGDIWPGLSAYDXSPRSPHSPSPIATPPSQSS 238

Query: 241 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS 300
           SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS
Sbjct: 239 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS 298

Query: 301 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLK 338
           PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLK
Sbjct: 299 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLK 336



 Score =  643 bits (1658), Expect = 0.0
 Identities = 397/749 (53%), Positives = 449/749 (59%), Gaps = 128/749 (17%)

Query: 13  SKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNNRGMRRPYG 72
           S+S S S +   S  HS K   S  S S  +S  RS                        
Sbjct: 235 SQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERS------------------------ 270

Query: 73  YRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRS 132
               G G    G  RY      P+ +    RSP +  +   +P        R  SR R S
Sbjct: 271 ----GSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAP--------RDESRGRSS 318

Query: 133 YRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAE-GEPQEESPLKSKSQEEPKDTF 191
           +      + ++             KR   +E +    + G  +++   K K  E+ +   
Sbjct: 319 FYPDGGDQETAKTGK-------FLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEG 371

Query: 192 EHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTV 251
           E +  E++D F+   +       G   +++S       +       +S         +T 
Sbjct: 372 EWEDQEALDYFSDKES-------GKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATA 424

Query: 252 HSAKNTPSQHSHSIQHSPERSGSGS-VGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNA 310
            S +NT  +    +++  + S  G+   +G       ++    ++  R S  K    ++ 
Sbjct: 425 -SHRNTEEE---GLKYKSKVSLKGNRESDGFREEKNDKHKETGYVVERPSTTKD---KHK 477

Query: 311 PRDESRGRSSFYPDGGDQETAKTGK----FLKSPPLHKNLDAREKSTFREESPLRIKMIA 366
             D++  R +   +    E  K+ K    F  SPPLHKNLDAREKSTFREESPLRIKMIA
Sbjct: 478 EEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIA 537

Query: 367 SDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASK 426
           SDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASK
Sbjct: 538 SDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASK 597

Query: 427 STSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISP 486
           STSESFIQHIVSLVHHVKEQYFKSAAMTL+ERFTSYQKATEEHSTRQKSPEIHRRIDISP
Sbjct: 598 STSESFIQHIVSLVHHVKEQYFKSAAMTLSERFTSYQKATEEHSTRQKSPEIHRRIDISP 657

Query: 487 STLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSG 546
           STLRK TRLAGEERVFKEENQKGDKKLRCDSADLRHDID RRKERSKERGDSKGSRES G
Sbjct: 658 STLRKDTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDHRRKERSKERGDSKGSRESRG 717

Query: 547 SRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKT 606
           SRKQEKTPKDYKEYKSYKDDSKHKREQDHS SSSSSASPSSPSSREEKESKKEREEEFKT
Sbjct: 718 SRKQEKTPKDYKEYKSYKDDSKHKREQDHSLSSSSSASPSSPSSREEKESKKEREEEFKT 777

Query: 607 HHEMKEYSGFAGVSRPRGTFFRIRG--------RGRARGVFAGTNTGPNNSNTTFQKRPK 658
           HHEMKEYSGFAGVSRPRGTF   R         RGR RG F                   
Sbjct: 778 HHEMKEYSGFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTF------------------- 818

Query: 659 EEEWDPEYTPKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDK 718
                                        +RGR         GRFNFKKSGSSPKW HDK
Sbjct: 819 -----------------------------QRGR---------GRFNFKKSGSSPKWNHDK 840

Query: 719 YQGDGIVEDEEETMENNEEKKDRRKEEKE 747
           YQGDGIVEDEEETMENNEEKKDR KEEKE
Sbjct: 841 YQGDGIVEDEEETMENNEEKKDRCKEEKE 869



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 31/112 (27%), Positives = 47/112 (41%), Gaps = 25/112 (22%)

Query: 3   RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYR 62
           + +S+    +  S S SSS S S   SR+++ S + R   +               ++Y 
Sbjct: 735 KDDSKHKREQDHSLSSSSSASPSSPSSREEKESKKEREEEFKTHHEM---------KEYS 785

Query: 63  NNRGMRRPYGY--------------RGRGRGYYQGGGGRYH--RGGYRPVWN 98
              G+ RP G               RGRGRG +Q G GR++  + G  P WN
Sbjct: 786 GFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWN 837



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 53/230 (23%), Positives = 95/230 (41%), Gaps = 28/230 (12%)

Query: 6   SRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNNR 65
           S   +S  K+  + S+R +S    R+   S  S  R  +R    +R++  + ++  +  R
Sbjct: 627 SERFTSYQKATEEHSTRQKSPEIHRRIDISP-STLRKDTRLAGEERVFKEENQKGDKKLR 685

Query: 66  ----GMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKR-RSV 120
                +R    +R + R   +G              + + SR  R  R + ++PK  +  
Sbjct: 686 CDSADLRHDIDHRRKERSKERG--------------DSKGSRESRGSRKQEKTPKDYKEY 731

Query: 121 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTK-KAEGEPQEESPL 179
            S +  S+ +R    S S    SS S+SP S S   ++   +E++ + K   E +E S  
Sbjct: 732 KSYKDDSKHKREQDHSLS----SSSSASPSSPSSREEKESKKEREEEFKTHHEMKEYSGF 787

Query: 180 KSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSP 229
              S+  P+ TF  D  + +D + K     G    G   + N  +S  SP
Sbjct: 788 AGVSR--PRGTFHDDRDDGVDYWAKRGRGRGTFQRGRGRF-NFKKSGSSP 834



 Score = 35.4 bits (80), Expect = 0.19
 Identities = 43/186 (23%), Positives = 78/186 (41%), Gaps = 25/186 (13%)

Query: 460 TSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSAD 519
           +S  K+  + S+R +S   H R     S  R ++R    +R++  + ++  +  R     
Sbjct: 10  SSRSKSRSQSSSRSRSRS-HSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNNRA---- 64

Query: 520 LRHDIDRRRKERSKERG--------------DSKGSRESSGSRKQEKTPKDYKEYKSYKD 565
           +R     R + R   +G              + + SR     R + ++PK  +   S + 
Sbjct: 65  MRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKR-RSVSSQRS 123

Query: 566 DSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKT---HHEMKEYSGFAGVSR- 621
            S+ +R    SRS  SS+S SS    +   SK+   +E +T     E++E S     S+ 
Sbjct: 124 RSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGELQEESPLKSKSQE 183

Query: 622 -PRGTF 626
            P+ TF
Sbjct: 184 EPKDTF 189



 Score = 33.5 bits (75), Expect = 0.74
 Identities = 40/195 (20%), Positives = 73/195 (37%), Gaps = 24/195 (12%)

Query: 564 KDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKER-------EEEFKTHHEMKEYSGF 616
           + +S+    +  SRS SSS S S   SR+++   + R        +   +    ++Y   
Sbjct: 3   RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNN 62

Query: 617 AGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEY--TPKSKKYF 674
             + RP G       RGR RG + G           + +      W+  +  +P+  +  
Sbjct: 63  RAMRRPYGY------RGRGRGYYQG-------GGGRYHRGGYRPVWNRRHSRSPRRGRSR 109

Query: 675 LHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSP--KWTHDKYQGDGIVEDEEETM 732
               +   V     R R R +++  R   +     SSP  K    K +G    + ++   
Sbjct: 110 SRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEG 169

Query: 733 ENNEEKKDRRKEEKE 747
           E  EE   + K ++E
Sbjct: 170 ELQEESPLKSKSQEE 184



 Score = 30.4 bits (67), Expect = 6.3
 Identities = 25/99 (25%), Positives = 41/99 (41%), Gaps = 20/99 (20%)

Query: 631 GRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYTPKSKKYFLHDDRDD--GVDY--- 685
           GR  +R   + ++   + S ++ + R +       Y  +S+ Y     RD     DY   
Sbjct: 2   GRSNSR---SHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRD 58

Query: 686 ----------WAKRGRGRGTFQRGRGRFNFKKSGSSPKW 714
                     +  RGRGRG +Q G GR++  + G  P W
Sbjct: 59  YRNNRAMRRPYGYRGRGRGYYQGGGGRYH--RGGYRPVW 95


>gi|167234419 thyroid hormone receptor associated protein 3 [Homo
           sapiens]
          Length = 955

 Score =  367 bits (942), Expect = e-101
 Identities = 297/834 (35%), Positives = 396/834 (47%), Gaps = 106/834 (12%)

Query: 2   GRSNSRSHSSRSKS-RSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD 60
           GRS SRS   RS S RS+S SR+  +S S + R SS SRS   S + SR     R   ++
Sbjct: 123 GRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRS---SSNHSRVESSKRKSAKE 179

Query: 61  YRNNRGMRRPYGYRGRGRG------YYQGG---------------------GGRYHRGGY 93
            +++    RP    G  +G       + GG                     G        
Sbjct: 180 KKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASRASAV 239

Query: 94  RPVWNRRHS--------------RSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSS--R 137
             +  R  S              RSPR       SP   S S   S   S   Y+S   +
Sbjct: 240 SELSPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSGAGYQSGTHQ 299

Query: 138 SPRSSSSRSSSPYSKSPVSKRR-------GSQEKQTKKAEGEP-------QEESPLKSKS 183
                 S S SP  KSPV K         GS +K+   A G         +E+     K 
Sbjct: 300 GQFDHGSGSLSPSKKSPVGKSPPSTGSTYGSSQKEESAASGGAAYTKRYLEEQKTENGKD 359

Query: 184 QEEPKDTFEHDPSESIDEFNKSSATSG----DIWPGLSAYDNSPRSPHSPSPIATPPSQS 239
           +E+ +   + +  +    F+ +    G    D +   +  +   R   SP          
Sbjct: 360 KEQKQTNTDKEKIKEKGSFSDTGLGDGKMKSDSFAPKTDSEKPFRGSQSPKRYKLRDDFE 419

Query: 240 SSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVG---NGSSRYSPSQNSPIHHIP 296
              +D          K+       S      +  S  +G   N     S      ++  P
Sbjct: 420 KKMADFHKEEMDDQDKDKAKGRKESEFDDEPKFMSKVIGANKNQEEEKSGKWEGLVYAPP 479

Query: 297 SRRSPAKT--IAPQNAP---RDESRGRSS------FYPDGGDQETAKTGKFLKS--PPLH 343
            +    KT  +  ++ P   + E RG+ S      F P+   + TA      KS  PP  
Sbjct: 480 GKEKQRKTEELEEESFPERSKKEDRGKRSEGGHRGFVPEKNFRVTAYKAVQEKSSSPPPR 539

Query: 344 KNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLV 403
           K  ++R+K   + + P   K   S +   +V ++M     D +     L ++R L   LV
Sbjct: 540 KTSESRDKLGAKGDFPTG-KSSFSITREAQVNVRMDSFDEDLARPSGLLAQERKLCRDLV 598

Query: 404 HSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQ 463
           HS KKEQEFRSIF HI+  Q+ +S SE F QHIV++VHHVKE +F S+ MTL+ERFT Y 
Sbjct: 599 HSNKKEQEFRSIFQHIQSAQSQRSPSELFAQHIVTIVHHVKEHHFGSSGMTLHERFTKYL 658

Query: 464 K--ATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLR 521
           K    +E +  +KSPEIHRRIDISPST RKH     E +  +E   K + K + D  DLR
Sbjct: 659 KRGTEQEAAKNKKSPEIHRRIDISPSTFRKHGLAHDEMKSPREPGYKAEGKYKDDPVDLR 718

Query: 522 HDIDRRRK--ERSKERGDSK---GSRESSGSRKQ--EKTPKDYKEYKSYKDDSKHKREQD 574
            DI+RR+K  ER  +RG S+    SR+SS SR++  EKT K +K  K  K   KH+R +D
Sbjct: 719 LDIERRKKHKERDLKRGKSRESVDSRDSSHSRERSAEKTEKTHKGSKKQK---KHRRARD 775

Query: 575 HSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEM-----KEYSGFA--GVSRPRGTF- 626
            SRSSSSS+  S     EE   + E  EE  T  +      K++ G +  G  R RGTF 
Sbjct: 776 RSRSSSSSSQSSHSYKAEEYTEETEEREESTTGFDKSRLGTKDFVGPSERGGGRARGTFQ 835

Query: 627 FRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYTPKSKKYFLHDDRD-DGVDY 685
           FR RGRG  RG ++G N   NNSN  FQKR +EEEWDPEYTPKSKKY+LHDDR+ +G D 
Sbjct: 836 FRARGRGWGRGNYSGNNN--NNSNNDFQKRNREEEWDPEYTPKSKKYYLHDDREGEGSDK 893

Query: 686 WAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQG-DGIVEDEEETMENNEEK 738
           W  RGRGRG F RGRGRF F+KS +SPKW HDK+ G +G +ED+E   EN EEK
Sbjct: 894 WVSRGRGRGAFPRGRGRFMFRKSSTSPKWAHDKFSGEEGEIEDDESGTENREEK 947



 Score =  189 bits (479), Expect = 1e-47
 Identities = 195/639 (30%), Positives = 301/639 (47%), Gaps = 73/639 (11%)

Query: 2   GRSNSRSHS-SRSKSRSQSSSRSRSRS--HSRKKRYSSRSRSRTYSRSRSRDRMYSRDYR 58
           G  +SRS S SRS+SRS S SRSRSRS   SRK+R SSRSRSR+YS + +R+R + R Y+
Sbjct: 10  GSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAHNRERNHPRVYQ 69

Query: 59  -RDYR-NNRGMRRPYGYRGRGRGYYQGGGGRYHRGG---YRPVW-NRRHSRSPRRGRSRS 112
            RD+R +NRG RRPY +RGR RG+Y    G+Y+RGG   YR  W N R + SPRRGRSRS
Sbjct: 70  NRDFRGHNRGYRRPYYFRGRNRGFYP--WGQYNRGGYGNYRSNWQNYRQAYSPRRGRSRS 127

Query: 113 RSPKRRSVSSQRSRSRSRRSYRSS--RSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAE 170
           RSPKRRS  S RSRS SR S +SS  RS RSSSSRSSS +S+   SKR+ ++EK++   +
Sbjct: 128 RSPKRRS-PSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAKEKKSSSKD 186

Query: 171 GEPQEESPLKSKSQEEPKDTF------EHDPSESIDEFNKSSATSGDIWPGLSAYDNSP- 223
             P + +   ++  E  + TF      +   SES   +  ++  +G      +  + SP 
Sbjct: 187 SRPSQAAG-DNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASRASAVSELSPR 245

Query: 224 -RSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGS--GSVGNG 280
            RSP   SP+ +   +  S   +P+        +T    S     +  +SG+  G   +G
Sbjct: 246 ERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSGAGYQSGTHQGQFDHG 305

Query: 281 SSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKSP 340
           S   SPS+ SP+      +SP  T +   + + E    S     GG    A T ++L+  
Sbjct: 306 SGSLSPSKKSPV-----GKSPPSTGSTYGSSQKEESAAS-----GG---AAYTKRYLEEQ 352

Query: 341 PLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKM-APVPLDDSNRPASLTKDRLLA 399
                 D  +K T  ++  ++ K   SD+   + K+K  +  P  DS +P   ++     
Sbjct: 353 KTENGKDKEQKQTNTDKEKIKEKGSFSDTGLGDGKMKSDSFAPKTDSEKPFRGSQS---- 408

Query: 400 STLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERF 459
                   K  + R  F+  K+    K   +   +         K +  K +      +F
Sbjct: 409 -------PKRYKLRDDFEK-KMADFHKEEMDDQDKD--------KAKGRKESEFDDEPKF 452

Query: 460 TSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSAD 519
            S      ++   +KS +    +   P   ++      EE  F E ++K D+  R +   
Sbjct: 453 MSKVIGANKNQEEEKSGKWEGLVYAPPGKEKQRKTEELEEESFPERSKKEDRGKRSEGGH 512

Query: 520 LRHDIDRRRK----ERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDH 575
                ++  +    +  +E+  S   R++S SR +     D+   KS    S  +  Q +
Sbjct: 513 RGFVPEKNFRVTAYKAVQEKSSSPPPRKTSESRDKLGAKGDFPTGKS--SFSITREAQVN 570

Query: 576 SRSSSSSASPSSPSSREEKESK--------KEREEEFKT 606
            R  S     + PS    +E K         ++E+EF++
Sbjct: 571 VRMDSFDEDLARPSGLLAQERKLCRDLVHSNKKEQEFRS 609



 Score = 38.9 bits (89), Expect = 0.018
 Identities = 46/195 (23%), Positives = 73/195 (37%), Gaps = 13/195 (6%)

Query: 4   SNSRSHSSRSKSRSQSSSRSRSRSHSRK-KRYSSRSRSRTYSRSR-SRDRMYSRDYRRDY 61
           S  +    R++ RS+SSS S   SHS K + Y+  +  R  S +   + R+ ++D+    
Sbjct: 764 SKKQKKHRRARDRSRSSSSSSQSSHSYKAEEYTEETEEREESTTGFDKSRLGTKDFVGPS 823

Query: 62  RNNRGMRR-PYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 120
               G  R  + +R RGRG+   G G Y         N  ++   +R R     P+    
Sbjct: 824 ERGGGRARGTFQFRARGRGW---GRGNYSGNNN----NNSNNDFQKRNREEEWDPEYTPK 876

Query: 121 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQ--TKKAEGEPQE-ES 177
           S +      R    S +       R + P  +     R+ S   +    K  GE  E E 
Sbjct: 877 SKKYYLHDDREGEGSDKWVSRGRGRGAFPRGRGRFMFRKSSTSPKWAHDKFSGEEGEIED 936

Query: 178 PLKSKSQEEPKDTFE 192
                   E KD  +
Sbjct: 937 DESGTENREEKDNIQ 951



 Score = 35.8 bits (81), Expect = 0.15
 Identities = 76/364 (20%), Positives = 120/364 (32%), Gaps = 63/364 (17%)

Query: 424 ASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRID 483
           AS+S S SF +   S          +   ++   R  SY  A   H+  +  P +++  D
Sbjct: 19  ASRSRSRSFSK---SRSRSRSLSRSRKRRLSSRSRSRSYSPA---HNRERNHPRVYQNRD 72

Query: 484 ISPST--LRKHTRLAGEERVFK---EENQKGDKKLRCDSADLRHDIDRRRKERSKERGDS 538
                   R+     G  R F    + N+ G    R +  + R     RR  RS+ R   
Sbjct: 73  FRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQAYSPRRG-RSRSRSPK 131

Query: 539 KGS---RESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKE 595
           + S   R  S SR  +K+  D       +  S  +   +HSR  SS    +       K+
Sbjct: 132 RRSPSPRSRSHSRNSDKSSSDRS-----RRSSSSRSSSNHSRVESSKRKSAKEKKSSSKD 186

Query: 596 SKKEREEEFKTHHEMKEYSGFAGVSR-----------PRGTFFRIRGRGRARGVFAGTNT 644
           S+  +        E KE +   G S+           P  T+    G G A    A +  
Sbjct: 187 SRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATY----GTGSASRASAVSEL 242

Query: 645 GPNNSNTTF----------QKRPKEEEWDPEYTPKSKKYFLHDDRDDGVDYWAKRGRGRG 694
            P   +             ++ P+         P S    +      G  Y  + G  +G
Sbjct: 243 SPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSGAGY--QSGTHQG 300

Query: 695 TFQRGRGRFNFKKS---GSSPKWTHDKYQGDGIVED-------------EEETMENNEEK 738
            F  G G  +  K    G SP  T   Y      E              EE+  EN ++K
Sbjct: 301 QFDHGSGSLSPSKKSPVGKSPPSTGSTYGSSQKEESAASGGAAYTKRYLEEQKTENGKDK 360

Query: 739 KDRR 742
           + ++
Sbjct: 361 EQKQ 364



 Score = 30.0 bits (66), Expect = 8.2
 Identities = 45/218 (20%), Positives = 74/218 (33%), Gaps = 38/218 (17%)

Query: 564 KDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKER-------------EEEFKTHHEM 610
           K  S+  R +  SRS S S S S   SR    S+K R                 + H  +
Sbjct: 8   KSGSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAHNRERNHPRV 67

Query: 611 KEYSGFAGVSRPRGTFFRIRGRGRA--------RGVFAGTNTGPNNSNTTFQ-KRPKEEE 661
            +   F G +R     +  RGR R         RG +    +   N    +  +R +   
Sbjct: 68  YQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQAYSPRRGRSRS 127

Query: 662 WDPEY---TPKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSG--------- 709
             P+    +P+S+ +  + D+    D   +    R +    R   + +KS          
Sbjct: 128 RSPKRRSPSPRSRSHSRNSDKSSS-DRSRRSSSSRSSSNHSRVESSKRKSAKEKKSSSKD 186

Query: 710 SSPKWTHDKYQGDGIVEDEEETMENNEEKKDRRKEEKE 747
           S P       QGD   E +E+T      +  +  E  +
Sbjct: 187 SRPSQAAGDNQGD---EAKEQTFSGGTSQDTKASESSK 221


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score =  109 bits (273), Expect = 8e-24
 Identities = 185/681 (27%), Positives = 269/681 (39%), Gaps = 131/681 (19%)

Query: 2    GRSNSRSHSSRSKSRSQSSSR-SRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSR----D 56
            GRS+SRS ++R +SRS++ +R  RSRS +  +R   RSRSRT +R RSR R  +R     
Sbjct: 560  GRSHSRSPATRGRSRSRTPARRGRSRSRTPARR---RSRSRTPTRRRSRSRTPARRGRSR 616

Query: 57   YRRDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSP-RRGRSRSRSP 115
             R   R     R P   R R R   +  G    R   R    R  SR+P RRGRSRSR+P
Sbjct: 617  SRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARR--GRSRSRTPARRGRSRSRTP 674

Query: 116  KRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQE 175
             RRS  S RSR+ +RR    SR+PR   SRS S         RRG    +T +  G    
Sbjct: 675  ARRSGRS-RSRTPARRGRSRSRTPRRGRSRSRS-------LVRRGRSHSRTPQRRGRSGS 726

Query: 176  ESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSP--------- 226
             S  K+KS+   +       S S  E  KS  +S       S   +SPRS          
Sbjct: 727  SSERKNKSRTSQR----RSRSNSSPEMKKSRISS-----RRSRSLSSPRSKAKSRLSLRR 777

Query: 227  ----HSPSP---IATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGN 279
                 SP P     TPP +S S S  P      +   TP + S S    P +  S +   
Sbjct: 778  SLSGSSPCPKQKSQTPPRRSRSGSSQP-----KAKSRTPPRRSRSSSSPPPKQKSKT--- 829

Query: 280  GSSRYSPSQNSPIHHIPSRRSP--AKTIAPQNAPRDESRGRSSFYPDGGDQE-----TAK 332
              SR S S +SP   + S   P      +PQ   +  +  R S +    D E      ++
Sbjct: 830  -PSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSR 888

Query: 333  TGKFLKSPPLHKNLDAREKSTFREESPL-RIKMIASDSHRPEVKLKMAPVPLDDSNR--- 388
                  SPP  K+     +S  R  SP  ++K I S   R       +P P   ++R   
Sbjct: 889  HSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSH-SGSSSPSPSRVTSRTTP 947

Query: 389  -------PASLTKDRLL-------ASTLVHSVKKEQEFR-----SIFDHIKL-------- 421
                   P S  + RLL       +S+    VK E   R     SI  + K+        
Sbjct: 948  RRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGP 1007

Query: 422  -------PQASKSTSESFIQHI---VSLVHHVK------EQYFKSAAMTLNERFTSYQKA 465
                   P   + + +S +Q     +SL   VK      E YF  +++ L        + 
Sbjct: 1008 SLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLK----GQSQT 1063

Query: 466  TEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDID 525
            + +H +   SPE+ +    SPS               + ++Q   K  R  S+    ++ 
Sbjct: 1064 SPDHRSDTSSPEVRQSHSESPS--------------LQSKSQTSPKGGRSRSSSPVTELA 1109

Query: 526  RRRKERSKERGDSKGS--RESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSA 583
             R   R ++RG+   S   +S  S +Q +   D   Y +   DS     Q    ++ S  
Sbjct: 1110 SRSPIR-QDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTV--DSNSLLGQSRLETAESKE 1166

Query: 584  SPSSPSSREEKESKKEREEEF 604
              + P   +   S   ++++F
Sbjct: 1167 KMALPPQEDATASPPRQKDKF 1187



 Score = 97.1 bits (240), Expect = 5e-20
 Identities = 119/393 (30%), Positives = 159/393 (40%), Gaps = 49/393 (12%)

Query: 2   GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSS---RSRSRT-----YSRSRSRDRMY 53
           GRS SR+ + R  SRS+S    RSRS  R  R  S   R RSR+     +SRSR+  R  
Sbjct: 493 GRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQR-- 550

Query: 54  SRDYRRDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSR 113
            R   R  R  R   R    RGR R       GR       P   R  SR+P R RSRSR
Sbjct: 551 -RGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSR--SRTPARRRSRSRTPTRRRSRSR 607

Query: 114 SPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSP-----YSKSPVSKRRGSQEKQTKK 168
           +P RR  S  RSR+ +RR  R +RSP    SRS SP      S+S    RRG    +T  
Sbjct: 608 TPARRGRS--RSRTPARRRSR-TRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPA 664

Query: 169 AEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHS 228
             G  +  +P +   +   +       S S       S +   +  G S         HS
Sbjct: 665 RRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRS---------HS 715

Query: 229 PSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQ 288
            +P     S SSS             K+  SQ       SPE   S      SSR S S 
Sbjct: 716 RTPQRRGRSGSSS---------ERKNKSRTSQRRSRSNSSPEMKKS----RISSRRSRSL 762

Query: 289 NSPIHHIPSRRSPAKTIAPQN-APRDESRGRSSFYPDGGDQETAKTGKFLKSPPLHKNLD 347
           +SP     SR S  ++++  +  P+ +S+        G  Q  AK+    ++PP      
Sbjct: 763 SSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKS----RTPPRRSRSS 818

Query: 348 AREKSTFREESPLRIKMIASDSHRPEVKLKMAP 380
           +      + ++P R    +S  H P+VK    P
Sbjct: 819 SSPPPKQKSKTPSRQSHSSSSPH-PKVKSGTPP 850



 Score = 75.1 bits (183), Expect = 2e-13
 Identities = 145/676 (21%), Positives = 246/676 (36%), Gaps = 71/676 (10%)

Query: 16  RSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNNRGMRRPYGYRG 75
           R  SSSRS +    +KK+   R R R+ S S  R+R  S   ++    +   +R      
Sbjct: 175 RESSSSRSPTPKQKKKKKKKDRGR-RSESSSPRRERKKSSKKKKHRSESESKKRK----- 228

Query: 76  RGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRS 135
                        HR       ++R S+  +R RSRS +P            +SRR++RS
Sbjct: 229 -------------HRSPTPK--SKRKSKDKKRKRSRSTTP----------APKSRRAHRS 263

Query: 136 SRSPRSSSSRSSSPYSKSPVSKR-------RGSQEKQTKKAEGE-PQEESPLKSKSQEEP 187
           + +  +SSS +S   S+S  +K        R       ++ EG+ P  E    S  +   
Sbjct: 264 TSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSS 323

Query: 188 KDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATP-PSQSSSCSDAP 246
            +T    PS   ++ +K         P  S  + S   P  P+P  TP  ++    S  P
Sbjct: 324 PETATKQPSSPYEDKDKDKKEKSATRPSPSP-ERSSTGPEPPAP--TPLLAERHGGSPQP 380

Query: 247 MLSTVHSAK--NTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKT 304
           + +T  S +  N PS+ S +   SP +S      + SS  SP    P     SR + +  
Sbjct: 381 LATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTK--VSRHASSSP 438

Query: 305 IAPQNAPRDESRGRSSFYPDGGDQE--TAKTGKFLKSPPLHKNLDAREKSTF---REESP 359
            +P+ AP   S    S  P   ++    AK  K     P  +   +R  +T    R  S 
Sbjct: 439 ESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSR 498

Query: 360 LRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDR------LLASTLVHSVKKEQEFR 413
              K   S S  P+ +   +      S  P    + R         S       + +  R
Sbjct: 499 TPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSAR 558

Query: 414 SIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQ 473
               H + P A++  S S                 +S + T   R +  +       +R 
Sbjct: 559 RGRSHSRSP-ATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRS 617

Query: 474 KSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSK 533
           ++P   R    SP   R  +R +   R  +  ++   ++ R  S         R +  ++
Sbjct: 618 RTPARRRSRTRSPVRRRSRSR-SPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPAR 676

Query: 534 ERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREE 593
             G S+    +   R + +TP+  +     +  S  +R + HSR+        S S R+ 
Sbjct: 677 RSGRSRSRTPARRGRSRSRTPRRGRS----RSRSLVRRGRSHSRTPQRRGRSGSSSERKN 732

Query: 594 KESKKEREEEFKTHHEMKE----YSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNS 649
           K    +R     +  EMK+          +S PR    + + R   R   +G++  P   
Sbjct: 733 KSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRS---KAKSRLSLRRSLSGSSPCPKQK 789

Query: 650 NTTFQKRPKEEEWDPE 665
           + T  +R +     P+
Sbjct: 790 SQTPPRRSRSGSSQPK 805



 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 116/456 (25%), Positives = 164/456 (35%), Gaps = 69/456 (15%)

Query: 2    GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSR------ 55
            GRS S       +SRS+S       +  R +  SS+S SR   RSRSR R+  R      
Sbjct: 1760 GRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSG 1819

Query: 56   ----------DYRRDYRNNRG-MRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRR-HSR 103
                        R   R  RG  R P   R R R        +  R    P  +RR  SR
Sbjct: 1820 YHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSR 1879

Query: 104  SPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQE 163
            +P   R RSRS +   VS +RSRSR+  + R SRS  S  SR  S     PV++RR    
Sbjct: 1880 TPLISRRRSRS-RTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSR 1938

Query: 164  KQT--KKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDN 221
              T  +++       +  +S+S+  P          S     +S + +  +    S    
Sbjct: 1939 TPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRT 1998

Query: 222  SP----RSPHSPSPIA-------TPPS-QSSSCSDAPMLSTVHSAKNTP----------- 258
            SP    RS    SP+        TPP+ +  S S  P+L    S   +P           
Sbjct: 1999 SPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRT 2058

Query: 259  ---SQHSHSIQHSP----ERSGSGSVGNGSSRYSP--------SQNSPIHHIPSRRSPAK 303
               ++   S+  SP     RS SGS  + S   +P        S+  P+    SR S   
Sbjct: 2059 PRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFS 2118

Query: 304  TIAPQNAPRDESRGRSSFYPDGGDQETAKT-----GKFLKSP----PLHKNLDAREKSTF 354
              +    P D  R      P G  +          G  +  P    P H+     E    
Sbjct: 2119 RPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHA- 2177

Query: 355  REESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPA 390
            +    L +  I+  + RP   +  A +    S  PA
Sbjct: 2178 QSRIALALTAISLGTARPPPSMSAAGLAARMSQVPA 2213



 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 112/416 (26%), Positives = 155/416 (37%), Gaps = 57/416 (13%)

Query: 3    RSNSRSHSSRSKS-RSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDY 61
            R+ + S   RS S + +   RSRSRS   K R + R      S+S SR R  SR   R  
Sbjct: 1752 RTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVT 1811

Query: 62   RNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVS 121
            R  RG          G GY+     R           R  SR+P   R RSRS   R+  
Sbjct: 1812 RRRRG----------GSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRS---RTSP 1858

Query: 122  SQRSRSRSRRS---YRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESP 178
            +   RSRSR S   +R SRS     SR  S    SPVS+RR        +     +    
Sbjct: 1859 APWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPV 1918

Query: 179  LKSKSQEE-PKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSP----RSPHSPSPIA 233
             + +S+   P  T     S +     +S + +  +    S     P    RS    SPI 
Sbjct: 1919 SRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPIT 1978

Query: 234  TPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIH 293
               S+S +   +P+      ++ +P     S      RS +  V   + R S S+  P  
Sbjct: 1979 RRRSRSRT---SPVTRRRSRSRTSPVTRRRS------RSRTSPV---TRRRSRSRTPPAI 2026

Query: 294  HIPSRRSPAKTIAPQNAPRDESRGRSSF-YPDGGDQETAKTGK----FLKSPPLHKNLDA 348
                RRS ++T      PR  SR RS           T +T +      +SPP  +   A
Sbjct: 2027 R---RRSRSRT---PLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSA 2080

Query: 349  REKSTFREESPL----------RIKMIASDSHRPEV--KLKMAPVPLDDSNRPASL 392
               S+ R  S            R   +A +S R     +  M+P PLD    P  L
Sbjct: 2081 SGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGML 2136



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 135/608 (22%), Positives = 207/608 (34%), Gaps = 94/608 (15%)

Query: 3    RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYS-SRSRSRTYSRSRSRDRMYSRDYRRDY 61
            RS+  S S  S    + +  S ++S S     +  R+ SR  S S S   M     R   
Sbjct: 1377 RSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPS 1436

Query: 62   RNNRGMRRPYGYRGRGRGYYQGGG--GRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRS 119
            R +R         G   G   G G   R+   G  P   +   R+P RGRS   S     
Sbjct: 1437 RRSRS--------GSSPGLRDGSGTPSRHSLSGSSPGM-KDIPRTPSRGRSECDSSPEPK 1487

Query: 120  VSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPL 179
               Q  R RS          RS SS   +    +P  +R GS+    +K        +PL
Sbjct: 1488 ALPQTPRPRS----------RSPSSPELNNKCLTPQRERSGSESSVDQKTVA----RTPL 1533

Query: 180  KSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQS 239
              +S+       +  PS S  E ++S +                 SP S +   TP  Q 
Sbjct: 1534 GQRSRSGSSQELDVKPSASPQERSESDS-----------------SPDSKAKTRTPLRQR 1576

Query: 240  SSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRR 299
            S    +P + +   ++ +P +          RSGS        R +P   S     P  +
Sbjct: 1577 SRSGSSPEVDS--KSRLSPRR---------SRSGSSPEVKDKPRAAPRAQSGSDSSPEPK 1625

Query: 300  SPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKSPPLHKNLDAREKSTFREESP 359
            +P    AP+  PR    G SS       + ++ T    + PP  K+  AR  S       
Sbjct: 1626 AP----APRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPP--KSRTARRGS------- 1672

Query: 360  LRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHI 419
                     S  P+ K +  P      + P    K RL   +   S   E   R+   H 
Sbjct: 1673 -------RSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHR 1725

Query: 420  KLPQ------ASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLN--ERFTSYQKATEEHST 471
            + P       A KS S    +   S       +  +S +      +R  S  +  +  +T
Sbjct: 1726 RSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTT 1785

Query: 472  RQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKER 531
            R++      R   S ST R+  R     RV +          R  +       +  R   
Sbjct: 1786 RRRD-----RSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQ-----ESSRTSS 1835

Query: 532  SKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSR--SSSSSASPSSPS 589
             + RG S+    S    +   +P  +K  +S    + H+R +  +   S   S S +SP 
Sbjct: 1836 RRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPV 1895

Query: 590  SREEKESK 597
            SR    S+
Sbjct: 1896 SRRRSRSR 1903



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 124/620 (20%), Positives = 212/620 (34%), Gaps = 80/620 (12%)

Query: 95  PVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSP 154
           P   ++  +  R  RS S SP+R     +R +S  ++ +RS    +    RS +P SK  
Sbjct: 185 PKQKKKKKKKDRGRRSESSSPRR-----ERKKSSKKKKHRSESESKKRKHRSPTPKSKR- 238

Query: 155 VSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWP 214
             K +  + K+++     P+     +S S +    +   D S S    + ++ T      
Sbjct: 239 --KSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSS---DTSRSRSR-SAAAKTHTTALA 292

Query: 215 GLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGS 274
           G S    S R     +P + P + S+    +P  +T    K   S +    +   E+S  
Sbjct: 293 GRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETAT----KQPSSPYEDKDKDKKEKS-- 346

Query: 275 GSVGNGSSRYSPS-QNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKT 333
                 ++R SPS + S     P   +P        +P+  +    S  P     E + T
Sbjct: 347 ------ATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPT 400

Query: 334 GKFLKSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLT 393
               +SPP  K+ +   +S+  E SP   +      H         P P   S+R  S +
Sbjct: 401 RD--RSPP--KSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSS 456

Query: 394 KDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAM 453
                                          SK+ S    +   S  H    +  +S + 
Sbjct: 457 P-----------------------------TSKNRSHGRAKRDKSHSHTPSRRMGRSRSP 487

Query: 454 TLNERFTSYQKA-TEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKK 512
              +R  S  +  T+   +R +SP+  R          +  +  G  R      + G  +
Sbjct: 488 ATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSR---SPQRPGWSR 544

Query: 513 LRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKRE 572
            R        +  RR + RS  RG S     ++  R + +TP      +S     +  R 
Sbjct: 545 SR--------NTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRS 596

Query: 573 QDHSRSSSSSASPSSPS-SREEKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFFRIRG 631
           +  +R  S S +P+    SR    +++            +  S      R R      RG
Sbjct: 597 RTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRG 656

Query: 632 RGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYTPKSKKYFLHDDRDDGVDYWAKRGR 691
           R R+R        G + S T  ++  +     P    +S+       R        +RGR
Sbjct: 657 RSRSR---TPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSL-VRRGR 712

Query: 692 GRGTFQRGRGRFNFKKSGSS 711
                 + RGR     SGSS
Sbjct: 713 SHSRTPQRRGR-----SGSS 727



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 58/210 (27%), Positives = 78/210 (37%), Gaps = 18/210 (8%)

Query: 111  RSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKA- 169
            RS S    S SS  S S S  S  SS S  S S  SS P       KR  S     K+A 
Sbjct: 2531 RSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAV 2590

Query: 170  -EGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHS 228
             EG P E +P K K +     +     S S    + SS++S       S+  +S  S  S
Sbjct: 2591 REGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPS 2650

Query: 229  P------------SPIATPPSQSSSCSDAPMLSTVHSAKNTP----SQHSHSIQHSPERS 272
            P            SP   PP +  S S    + ++  +++       +   S Q SP   
Sbjct: 2651 PAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQ 2710

Query: 273  GSGSVGNGSSRYSPSQNSPIHHIPSRRSPA 302
             S S   GS R     +    H   R +P+
Sbjct: 2711 QSSSSERGSRRGQRGDSRSPSHKRRRETPS 2740



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 97/340 (28%), Positives = 131/340 (38%), Gaps = 51/340 (15%)

Query: 3    RSNSRSHSS-RSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDY 61
            RS S S S  R  S   SSS   S  H  K R ++R  SR+    +++ R   R  RR  
Sbjct: 1635 RSRSGSSSKGRGPSPEGSSSTESSPEHPPKSR-TARRGSRSSPEPKTKSRTPPR--RRSS 1691

Query: 62   RNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRR-SV 120
            R++  + R      R R           R    P   R  S S      +SRS +RR S 
Sbjct: 1692 RSSPELTRKARLSRRSRS---ASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSA 1748

Query: 121  SSQRSRSRSRRSYRSSRSPRS-SSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPL 179
            SS R+++ SRR    S  PR    SRS S   K+  ++RR           G  Q  S  
Sbjct: 1749 SSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRR--------DRSGSSQSTSRR 1800

Query: 180  KSKSQEEPKDTFE-------HDPSESIDEFNKSSATSGDIWPGLS----AYDNSPRSPHS 228
            + +S+   + T         H  S +  E   SS TS     G S          RS  S
Sbjct: 1801 RQRSRSRSRVTRRRRGGSGYHSRSPARQE---SSRTSSRRRRGRSRTPPTSRKRSRSRTS 1857

Query: 229  PSP------IATPPSQSSSCSDAPMLSTVHSAKNTP------SQHSHSIQHSPERSGSGS 276
            P+P       A+P +   S S  P++S   S   T       S+   S+     RS +  
Sbjct: 1858 PAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASP 1917

Query: 277  VGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESR 316
            V   S R S S+  P   +  RRS ++T  P    R  SR
Sbjct: 1918 V---SRRRSRSRTPP---VTRRRSRSRT--PTTRRRSRSR 1949



 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 132/621 (21%), Positives = 209/621 (33%), Gaps = 80/621 (12%)

Query: 109  RSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPY----SKSPVSKRRGSQEK 164
            RS + SP+ R   S+    +S+    S  SP+   SRSSSP     S+SP+ + RG    
Sbjct: 1068 RSDTSSPEVRQSHSESPSLQSK----SQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSA 1123

Query: 165  QTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGD---IWPGLSAYDN 221
                  G   E+S  +S S   P      D +  + +    +A S +   + P   A  +
Sbjct: 1124 SPMLKSGMSPEQSRFQSDSSSYP----TVDSNSLLGQSRLETAESKEKMALPPQEDATAS 1179

Query: 222  SPRSPHSPSP----------------IATPPSQSSSCSDAPMLSTVHSAKNTPSQHSH-- 263
             PR     SP                + TPP + S    +P     +SA  T SQ     
Sbjct: 1180 PPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELM 1239

Query: 264  SIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPS-RRSPAKTIA---PQNAPRDESRGRS 319
             +    E      + + SS       S     P     PA ++     Q+    E+    
Sbjct: 1240 EVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVP 1299

Query: 320  SFYPDGGDQETAKTGKFLKSPPLHKNLDAREKSTFREESPLRIKM-------IASDSHRP 372
            S     G    +   K L + PL +N        FR   PL  +M       +  D + P
Sbjct: 1300 SMASSWGGPHFSPEHKELSNSPLREN-SFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGP 1358

Query: 373  EVKLKMAPVPLD---DSNRPASLTKDRLLASTLVHS-VKKEQEFRS-IFDHI-KLPQASK 426
             +        LD    S R +  +   L    +  + +   Q   S + D + + P   +
Sbjct: 1359 FLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRER 1418

Query: 427  STSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISP 486
            S+S S  +    L      +    ++  L +           HS    SP + + I  +P
Sbjct: 1419 SSSASSPEMKDGLPRTPSRRSRSGSSPGLRDG----SGTPSRHSLSGSSPGM-KDIPRTP 1473

Query: 487  STLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSK------- 539
            S  R     + E +   +  +   +       + +    +R +  S+   D K       
Sbjct: 1474 SRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPL 1533

Query: 540  GSRESSGSR-----KQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSR--- 591
            G R  SGS      K   +P++  E  S  D     R     RS S S+      SR   
Sbjct: 1534 GQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSP 1593

Query: 592  EEKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFFR-IRGRGRARGVFAGTNTGPNNSN 650
                S    E + K     +  SG      P+    R +  R R+     G    P  S+
Sbjct: 1594 RRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSS 1653

Query: 651  TTFQKRPKEEEWDPEYTPKSK 671
            +T        E  PE+ PKS+
Sbjct: 1654 ST--------ESSPEHPPKSR 1666



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 62/231 (26%), Positives = 92/231 (39%), Gaps = 23/231 (9%)

Query: 95   PVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSP 154
            P  +  +  SPR   S       R+      R+RSR    +    R +S R+ SP     
Sbjct: 2373 PALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSP----- 2427

Query: 155  VSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPK----DTFEHDPSESIDEFNKSSATS- 209
             S R G    Q+     + Q  SP+ S   ++ +     T     S+S+     ++ TS 
Sbjct: 2428 -SSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSS 2486

Query: 210  -GDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHS 268
             GD    LS    +P  PH  S +  PP+ S+       L+ +  AK   S  S S   S
Sbjct: 2487 AGDHNGMLSV--PAPGVPH--SDVGEPPA-STGAQQPSALAALQPAKERRSSSSSSSSSS 2541

Query: 269  PERSGSGSVGNGSSRYSPSQNSPIHHIP------SRRSPAKTIAPQNAPRD 313
               S S S  + SS  S S +S    +P       +R P+ T AP+ A R+
Sbjct: 2542 SSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVRE 2592



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 57/214 (26%), Positives = 82/214 (38%), Gaps = 16/214 (7%)

Query: 115  PKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEP- 173
            P   + + Q S   + +  +  RS  SSSS SSS  S S  S    S    +  +EG   
Sbjct: 2509 PPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSL 2568

Query: 174  --QEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSP 231
              Q E  LK      P       P E++ E      T        S+  +S  S  S S 
Sbjct: 2569 PVQPEVALKRVPSPTPA------PKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSS 2622

Query: 232  IATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSP 291
             ++  S SSS S +   S+  S+ ++PS      Q  P+ +       G  R S S   P
Sbjct: 2623 SSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERR-SRSPRKP 2681

Query: 292  IHHIPSRRS------PAKTIAPQNAPRDESRGRS 319
            I  +   RS        +  +PQ +PRD+    S
Sbjct: 2682 IDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSS 2715



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 50/166 (30%), Positives = 61/166 (36%), Gaps = 23/166 (13%)

Query: 104  SPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQE 163
            +P + + RS S    S SS  S S S  S  SS S  SSSS SSS  S SP   + G Q 
Sbjct: 2599 TPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQ- 2657

Query: 164  KQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSP 223
                     P+  SP K      P +     P + ID    S + S            SP
Sbjct: 2658 -------ALPKPASPKK----PPPGERRSRSPRKPIDSLRDSRSLS-----------YSP 2695

Query: 224  RSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSP 269
                 PSP  +P  Q SS S+            +PS        SP
Sbjct: 2696 VERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSP 2741



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 116/558 (20%), Positives = 187/558 (33%), Gaps = 94/558 (16%)

Query: 116  KRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQE 175
            +R +VS    +S+S+ S  +   P  +SS     +S                  E +   
Sbjct: 1276 ERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSP-----------------EHKELS 1318

Query: 176  ESPLKSKSQEEPKDTFEHDP----------SESIDEFNKSSATSGDIWPGLSAYDNSPRS 225
             SPL+  S   P +     P          SE  ++ N       +  P L   + S RS
Sbjct: 1319 NSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRS 1378

Query: 226  P-HSPSPIATPPSQSSSCSDAPMLST--VHSAKNTPSQHSHSIQHSPE-----------R 271
              HS S ++    + +  S    +S+  + +   TPS+   S   SPE           R
Sbjct: 1379 SGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRR 1438

Query: 272  SGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETA 331
            S SGS    S        +P  H  S  SP     P+   R  S   SS  P    Q   
Sbjct: 1439 SRSGS----SPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPR 1494

Query: 332  KTGKFLKSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPAS 391
               +   SP L+      ++     ES +  K +A     P  +   +    +   +P++
Sbjct: 1495 PRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVA---RTPLGQRSRSGSSQELDVKPSA 1551

Query: 392  LTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSA 451
              ++R  + +   S  K +          L Q S+S S   +                 +
Sbjct: 1552 SPQERSESDSSPDSKAKTRT--------PLRQRSRSGSSPEVD----------------S 1587

Query: 452  AMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDK 511
               L+ R +    + E     + +P      D SP         A   R     ++ G  
Sbjct: 1588 KSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPK------APAPRALPRRSRSGSS 1641

Query: 512  -KLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHK 570
             K R  S +     +   +   K R   +GSR S   + + +TP   +  +S  + ++  
Sbjct: 1642 SKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKA 1701

Query: 571  REQDHSRSSSS--------------SASPSSPSSREEKESKKEREEEFKTHHEMKEYSGF 616
            R    SRS+SS              S S SSP   E+  S + R        +     G 
Sbjct: 1702 RLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGR 1761

Query: 617  AGVSRPRGTFFRIRGRGR 634
            +   +PRG   R R R R
Sbjct: 1762 SPSPKPRG-LQRSRSRSR 1778



 Score = 46.6 bits (109), Expect = 8e-05
 Identities = 53/190 (27%), Positives = 67/190 (35%), Gaps = 39/190 (20%)

Query: 134  RSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEH 193
            RSS S  SSSS SSS  S S  S   GS    ++ +    Q E  LK      P      
Sbjct: 2531 RSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPA----- 2585

Query: 194  DPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHS 253
             P E++ E                        P  P+P       SSS S          
Sbjct: 2586 -PKEAVREGR----------------------PPEPTPAKRKRRSSSSSSS--------- 2613

Query: 254  AKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRD 313
              ++ S  S S   S   S S S  + SS  S S +SP    P  ++  K  +P+  P  
Sbjct: 2614 --SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPG 2671

Query: 314  ESRGRSSFYP 323
            E R RS   P
Sbjct: 2672 ERRSRSPRKP 2681



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 51/156 (32%), Positives = 62/156 (39%), Gaps = 22/156 (14%)

Query: 3    RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDY- 61
            R +S S SS S S S SSS S S S S     SS S S + S S S  +   +   +   
Sbjct: 2605 RRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPAS 2664

Query: 62   --------RNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSR 113
                    R +R  R+P       R              Y PV  RR S  P     +S 
Sbjct: 2665 PKKPPPGERRSRSPRKPIDSLRDSRSL-----------SYSPVERRRPSPQPSPRDQQSS 2713

Query: 114  SPKRRSVSSQR--SRSRSRRSYRSSRSPRSSSSRSS 147
            S +R S   QR  SRS S +  R + SPR    RSS
Sbjct: 2714 SSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSS 2749



 Score = 30.0 bits (66), Expect = 8.2
 Identities = 19/49 (38%), Positives = 20/49 (40%)

Query: 548  RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKES 596
            R  E TP   K   S    S        S SSSSS+S SS SS     S
Sbjct: 2594 RPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2642


>gi|115511057 hypothetical protein LOC256643 [Homo sapiens]
          Length = 682

 Score =  103 bits (258), Expect = 4e-22
 Identities = 154/644 (23%), Positives = 255/644 (39%), Gaps = 109/644 (16%)

Query: 4   SNSRSHSSRSKSRSQSSSRSRSRSHSRKK--------------------RYSSRSRSRTY 43
           + SRS S R K RS S    R+  H +++                    R  S    ++ 
Sbjct: 2   ARSRSRSPRWKHRSLSPV-PRNAEHYKQRHSHGHYGCEYRKDPKRPVAWRMDSEKHGQSK 60

Query: 44  SRSRSRDRMYSRDYRR-----DYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWN 98
            R  SR  +Y + Y       + RN+  +   Y Y+   RGY  G G    R  Y P ++
Sbjct: 61  PRIPSRGNIYYQSYEHRSPSPNIRNS--LENVYMYKPH-RGYSPGRGDSNRRAQYMPKYS 117

Query: 99  RRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSS---------- 148
                 P +   R+  P++          R R S +  + P+ S + S            
Sbjct: 118 EG---IPYKEHERNSYPQKVQGGHSPDDHRVRGSGKGGKPPQRSIADSFRFEGKWHEDEL 174

Query: 149 -----PYSKSPVSKRRGSQEKQTKKA--EGEPQEESPLK-SKSQEEPKDTFEHD------ 194
                   K   S RRGS++ +T+ +  +  P++    K   + + PKD   ++      
Sbjct: 175 RHQRIQEEKYSQSTRRGSEDFETRSSFQKRYPEDRDFRKYGHTSKRPKDVERYESREPAR 234

Query: 195 -----PSESIDEFNKSSATSGDIWP-GLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPML 248
                P  S+  + + +    D W  G   Y ++ R  H  +  AT  S         +L
Sbjct: 235 NPKWKPEHSLPPYQEDT----DQWNLGPQTYRHAERE-HPETSSATKVSYDYRHKRPKLL 289

Query: 249 STVHSAKNTPSQ-------HSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSP 301
                  +  +Q         +S Q  P          G  R   +Q+  +   P + S 
Sbjct: 290 DGDQDFSDGRTQKYCKEEDRKYSFQKGPLNRELDCFNTGRGR--ETQDGQVKE-PFKPSK 346

Query: 302 AKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKSPPLHKN-LDAREKSTFREESPL 360
             +IA   + +++   RSS   D   ++  K G   K      N LD  +K    + SP+
Sbjct: 347 KDSIACTYSNKNDVDLRSS--NDKWKEKIKKEGDCRKESNSSSNQLDKSQKLPDVKPSPI 404

Query: 361 RIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIK 420
            ++     S   +V +K     +D     +S + +R ++  LV   +K + F  +F+H+ 
Sbjct: 405 NLR---KKSLTVKVDVKKT---VDTFRVASSYSTERQMSHDLVAVGRKSENFHPVFEHLD 458

Query: 421 LPQ--ASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQ---KATEEHSTRQKS 475
             Q   +K T E F Q I++++H VK  YF S  +TL+ERF++ Q   KA          
Sbjct: 459 STQNTENKPTGE-FAQEIITIIHQVKANYFPSPGITLHERFSTMQDIHKADVNEIPLNSD 517

Query: 476 PEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKER 535
           PEIHRRID+S + L+       ++ V  E  Q   K +  D  DLRHDI+RRRKER +  
Sbjct: 518 PEIHRRIDMSLAELQ------SKQAVIYESEQTLIKII--DPNDLRHDIERRRKERLQNE 569

Query: 536 GD---------SKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHK 570
            +          +  + SS S+      KD   +K ++ +  H+
Sbjct: 570 DEHIFHIASAAERDDQNSSFSKNYTTQRKDIITHKPFEVEGNHR 613


>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
          Length = 715

 Score = 96.3 bits (238), Expect = 9e-20
 Identities = 98/347 (28%), Positives = 136/347 (39%), Gaps = 64/347 (18%)

Query: 2   GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDY 61
           G S+ R  S RS+S S +  R  SRS S  K    RSRSR+  ++R R R  S +  RD 
Sbjct: 379 GSSSPRKESGRSQSGSPNKQRDHSRSRSPNKA-RDRSRSRSPYKARDRSRSRSPNKARDC 437

Query: 62  RNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPR--RGRSRSRSPKRRS 119
             +R    PY  R R R         + R           SRSP   R RSRSRSP +  
Sbjct: 438 SRSRS---PYKARDRSRSRSPNKARDHSR-----------SRSPNKARDRSRSRSPSKER 483

Query: 120 VSSQRSRSRSRRSYRSSRSP---------RSSSSRSSSPYSKSPVSKRRGSQEKQTKKAE 170
             SQ       R +R SRSP         RSSS       S+SP  +R+  Q +   K  
Sbjct: 484 DHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKER 543

Query: 171 GEPQEESP--------LKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNS 222
              Q  SP         +S S+E  +  +     E     ++SS+   D         + 
Sbjct: 544 DRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERD--------HSR 595

Query: 223 PRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSS 282
            RSP+  S  + P + S                    + +HS   +P + G+ S    SS
Sbjct: 596 SRSPNKQSGYSRPRASS-------------------KEKAHSRSRTPSKEGNHSQSRTSS 636

Query: 283 RYSPSQNSPIHHIPS-RRSPAKT--IAPQNAPRDESRGRSSFYPDGG 326
           + S    S +   P  +RSP +T  ++    P   S    S +P GG
Sbjct: 637 KESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGG 683



 Score = 84.0 bits (206), Expect = 5e-16
 Identities = 154/679 (22%), Positives = 246/679 (36%), Gaps = 98/679 (14%)

Query: 3   RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYR 62
           R++  S SS   ++S S+ R+ S   S + R   RS++RT SR  +  R        D R
Sbjct: 53  RNSVMSPSSSKSTKSTSTKRAPSNRPSSRSRV--RSKARTPSRVSTDTRTSKASKASDVR 110

Query: 63  NNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSS 122
            ++  RR    RGR  G                   RR SRS +R  SR+ +P R     
Sbjct: 111 CHQ--RRGTHSRGRTPG-------------------RRGSRSSKRSPSRASTPGR----- 144

Query: 123 QRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSK 182
                      R+  +    +SR  +P S+   S+ +     +T   E    +   L  K
Sbjct: 145 ----------IRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQPRNLSKK 194

Query: 183 SQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIAT-----PPS 237
           S   P  +     SE     + +   +    P     DN   SP S   + +      PS
Sbjct: 195 SYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNP--SPSSSRKVKSYGQMIIPS 252

Query: 238 QSSSCSDAPMLSTVHS---AKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHH 294
           +  S S   M S V S   A       SHS   SP RS SGS     SR   S +   +H
Sbjct: 253 REKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVR-SHSWKRNH 311

Query: 295 IPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKSPPLHKNLDAREKSTF 354
             +R    K I  Q     +SR  S     G  Q  ++T +  +S    +N       + 
Sbjct: 312 SRARSRTRKGILSQMGRHSQSRSHSK----GKSQNQSRTPRRGRSHNWSRNPSKERSHSH 367

Query: 355 REESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRS 414
              S        S S R E     +  P    +   S + ++    +   S  K ++   
Sbjct: 368 SRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSR 427

Query: 415 IFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQK 474
                K    S+S S                  +K+       R  S  KA +   +R  
Sbjct: 428 SRSPNKARDCSRSRSP-----------------YKARD---RSRSRSPNKARDHSRSRSP 467

Query: 475 SPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLR-CDSADLRHDIDRRRKERSK 533
           +    R    SPS  R H++L    +       +   K R C          R+ +  SK
Sbjct: 468 NKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQC----------RQSRSSSK 517

Query: 534 ERGDSKGSRESS--GSRKQEKTP---KDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSP 588
           ER D + SR  S    R+Q ++P   +D  + +S  ++ +H++ +  S+        S  
Sbjct: 518 ER-DHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPS 576

Query: 589 SSREEKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFFRIRGRGRAR-----GVFAGTN 643
             RE ++S+   EE  + H   +  +  +G SRPR +  + +   R+R     G  + + 
Sbjct: 577 KERERRQSRSSSEE--RDHSRSRSPNKQSGYSRPRAS-SKEKAHSRSRTPSKEGNHSQSR 633

Query: 644 TGPNNSNTTFQKRPKEEEW 662
           T    S+ +    P+  +W
Sbjct: 634 TSSKESDPSQSTVPRSPDW 652



 Score = 79.0 bits (193), Expect = 2e-14
 Identities = 162/620 (26%), Positives = 233/620 (37%), Gaps = 72/620 (11%)

Query: 2   GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDY 61
           GR  SRS S RS SR+  S+  R R+H  +   +SR R+ T  +  SR + Y R   R  
Sbjct: 125 GRRGSRS-SKRSPSRA--STPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRP--RTS 179

Query: 62  RNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSP-KRRSV 120
              R   +P       + Y   GG    R     V     + S  + ++ +  P K +S 
Sbjct: 180 NRERSDSQPRNL--SKKSYRPPGGSGIGRSSELAV-----TPSTAKCQTPTGIPSKEKSD 232

Query: 121 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGS--QEKQTKKAEGEPQEESP 178
           +   S SR  +SY     P    S     YS + +S R  S  Q     + +   Q  SP
Sbjct: 233 NPSPSSSRKVKSYGQMIIPSREKS-----YSPTEMSSRVKSYNQASTRSRPQSHSQSRSP 287

Query: 179 LKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRS-PHSPSPIATPPS 237
            +S+S  + K T     S S    N S A S      LS      +S  HS         
Sbjct: 288 RRSRSGSQ-KRTHSRVRSHSWKR-NHSRARSRTRKGILSQMGRHSQSRSHS-------KG 338

Query: 238 QSSSCSDAPMLSTVHSAKNTPSQ---HSHSIQHSPERS--GSGSVGNGSSR-YSPSQNSP 291
           +S + S  P     H+    PS+   HSHS   S ER   GS S    S R  S S N  
Sbjct: 339 KSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQ 398

Query: 292 IHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKSPPLHKNLDAREK 351
             H  S RSP       N  RD SR RS +         A+     +SP   ++  +R +
Sbjct: 399 RDHSRS-RSP-------NKARDRSRSRSPY--------KARDRSRSRSPNKARDC-SRSR 441

Query: 352 STF--REESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKE 409
           S +  R+ S  R    A D  R       +P    D +R  S +K+R    + + S  KE
Sbjct: 442 SPYKARDRSRSRSPNKARDHSR-----SRSPNKARDRSRSRSPSKER--DHSQLGSPSKE 494

Query: 410 QEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKA---- 465
           ++ R      K  Q  +S S S  +         KE+  + +     ER  S  ++    
Sbjct: 495 RDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEE 554

Query: 466 TEEHSTRQKSPEIHRRIDISPS--TLRKHTRLAGEERVFKE----ENQKGDKKLRCDSAD 519
            E   +R  S E  RR   SPS    R+ +R + EER          Q G  + R  S +
Sbjct: 555 REHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKE 614

Query: 520 LRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSS 579
             H   R   +          S+ES  S+       D+K   +        R    + S 
Sbjct: 615 KAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSH 674

Query: 580 SSSASPSSPSSREEKESKKE 599
           S S  PS   +  + +S+ +
Sbjct: 675 SPSTFPSGGQTLSQDDSQAD 694



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 107/504 (21%), Positives = 180/504 (35%), Gaps = 84/504 (16%)

Query: 141 SSSSRSSSP-YSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESI 199
           SS  RSS P  S +P      + + +   +    +  +P +S    +P  +     S S 
Sbjct: 2   SSPKRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPSS 61

Query: 200 DEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPS 259
            +  KS++T         A  N P S       A  PS+ S+ +     S     +    
Sbjct: 62  SKSTKSTSTK-------RAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQR 114

Query: 260 QHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESR-GR 318
           + +HS   +P R GS S                    S+RSP++   P       +R G 
Sbjct: 115 RGTHSRGRTPGRRGSRS--------------------SKRSPSRASTPGRIRTHGARPGM 154

Query: 319 SSFYPDGGDQETAKTGKFLKSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKM 378
           +S       Q+    GK    P          +++ RE S  + + ++  S+RP      
Sbjct: 155 ASRVRTPTSQQKGSRGKSYGRP----------RTSNRERSDSQPRNLSKKSYRP------ 198

Query: 379 APVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVS 438
                     P      R     +  S  K Q    I    K    S S+S     +   
Sbjct: 199 ----------PGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQM 248

Query: 439 LVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGE 498
           ++   ++ Y   +   ++ R  SY +A+     +  S     R   S S  R H+R+   
Sbjct: 249 IIPSREKSY---SPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSH 305

Query: 499 ERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYK 558
              +K  + +   + R         I  +    S+ R  SKG      S+ Q +TP+  +
Sbjct: 306 S--WKRNHSRARSRTR-------KGILSQMGRHSQSRSHSKGK-----SQNQSRTPRRGR 351

Query: 559 EYKSYKDDSKHKREQDHSRSSS------SSASPSSPSSREEKESKKEREEEFKTHHEMKE 612
            +   ++ SK +R   HSRSSS       S+SP   S R +  S  ++ +    H   + 
Sbjct: 352 SHNWSRNPSK-ERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRD----HSRSRS 406

Query: 613 YSGFAGVSRPRGTFFRIRGRGRAR 636
            +     SR R   ++ R R R+R
Sbjct: 407 PNKARDRSRSRSP-YKARDRSRSR 429



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 113/536 (21%), Positives = 187/536 (34%), Gaps = 47/536 (8%)

Query: 110 SRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKA 169
           ++S +P R  V ++ + SR+     S  SP SS S  S+   ++P S R  S+ +   KA
Sbjct: 35  TKSATPNRSLVPTKPATSRN-----SVMSPSSSKSTKSTSTKRAP-SNRPSSRSRVRSKA 88

Query: 170 EGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSP 229
               +  +  ++    +  D   H          +    S    PG     +S RSP   
Sbjct: 89  RTPSRVSTDTRTSKASKASDVRCHQ---------RRGTHSRGRTPGRRGSRSSKRSPSRA 139

Query: 230 SPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSR--YSPS 287
           S      +  +    A  + T  S +      S+    +  R  S S     S+  Y P 
Sbjct: 140 STPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRPP 199

Query: 288 QNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKSPPLHKNLD 347
             S I      RS    + P  A      G  S   +  D  +  + + +KS      + 
Sbjct: 200 GGSGIG-----RSSELAVTPSTAKCQTPTGIPS--KEKSDNPSPSSSRKVKSYG-QMIIP 251

Query: 348 AREKSTFREESPLRIKMI--ASDSHRPEVKLKM-APVPLDDSNRPASLTKDRLLASTLVH 404
           +REKS    E   R+K    AS   RP+   +  +P      ++  + ++ R  +    H
Sbjct: 252 SREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNH 311

Query: 405 SVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQK 464
           S  + +  + I   +     S+S S+   Q+        +   +            S   
Sbjct: 312 SRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSS 371

Query: 465 ATEEHSTRQKSP--EIHRRIDISPSTLRKHTRLAG----EERVFKEENQKGDKKLRCDSA 518
           + E       SP  E  R    SP+  R H+R        +R       K   + R  S 
Sbjct: 372 SKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSP 431

Query: 519 DLRHDIDRRR-----KERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHK--- 570
           +   D  R R     ++RS+ R  +K +R+ S SR   K  +D    +S   +  H    
Sbjct: 432 NKARDCSRSRSPYKARDRSRSRSPNK-ARDHSRSRSPNKA-RDRSRSRSPSKERDHSQLG 489

Query: 571 ---REQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKEYSGFAGVSRPR 623
              +E+DH RS S S       SR   + +  R     +    +  S      R R
Sbjct: 490 SPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDR 545


>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
          Length = 494

 Score = 93.6 bits (231), Expect = 6e-19
 Identities = 100/288 (34%), Positives = 133/288 (46%), Gaps = 32/288 (11%)

Query: 4   SNSRSHS-SRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD-- 60
           S+S+S S SRS SRS+S SRSRS+S SR K+  SRS S+  SRSRS     SR   +D  
Sbjct: 214 SHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQA 273

Query: 61  ---YRNNRGMRRPYG-------------YRGRGRGYYQGGGGRYHRG-GYRPVWNRRHSR 103
               +NN  + +P                R + R   +   G   RG        +  SR
Sbjct: 274 EEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSR 333

Query: 104 SPRRGRSRSRSPKR-RSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQ 162
           S  +G SRSRS  R +S   ++ R RSR   RS    RS S RS    SK     + GS 
Sbjct: 334 SRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKR--DSKAGSS 391

Query: 163 EKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESID-EFNKSSATSGDIWPGLS-AYD 220
           +K+ K+     Q  SP +S S+E      EH  SES   E    S  +G      S +  
Sbjct: 392 KKKKKEDTDRSQSRSPSRSVSKER-----EHAKSESSQREGRGESENAGTNQETRSRSRS 446

Query: 221 NSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHS 268
           NS   P+ PS  +   S+S+S + +   S   SA  +PS+ S S  HS
Sbjct: 447 NSKSKPNLPSE-SRSRSKSASKTRSRSKSRSRSASRSPSR-SRSRSHS 492



 Score = 67.4 bits (163), Expect = 5e-11
 Identities = 74/224 (33%), Positives = 97/224 (43%), Gaps = 49/224 (21%)

Query: 1   MGRSNSRS---HSSRSKSRSQSSSR----------SRSRSHSRKKRYS-SRSRSRTYSRS 46
           +G+  SRS   H S+SKSRS+S  R          SR RS  +  R S SRSRS+  SRS
Sbjct: 283 VGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRS 342

Query: 47  RSRDRMYSRDYR------RDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRR 100
           RSR R  S+D R      R+   +R   R    R R RG  +       +   +   +R 
Sbjct: 343 RSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRS 402

Query: 101 HSRSPRRGRSRSRSPKRRSVSSQR----------------SRSRSRRSYRSSRSPRSSSS 144
            SRSP R  S+ R    +S SSQR                SRSRS  S      P  S S
Sbjct: 403 QSRSPSRSVSKERE-HAKSESSQREGRGESENAGTNQETRSRSRS-NSKSKPNLPSESRS 460

Query: 145 RSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPK 188
           RS S       SK R   + +++ A       SP +S+S+   +
Sbjct: 461 RSKS------ASKTRSRSKSRSRSA-----SRSPSRSRSRSHSR 493



 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 66/241 (27%), Positives = 91/241 (37%), Gaps = 16/241 (6%)

Query: 101 HSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRG 160
           + R  R    +  S +RRS S  RS SRSR   R SR  RS S  S S +SKS    R G
Sbjct: 166 NGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSG 225

Query: 161 SQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYD 220
           S+ +   K+    Q  S  K +    P        S S     KS + S D      A +
Sbjct: 226 SRSR--SKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSA---GKSRSKSKD-----QAEE 275

Query: 221 NSPRSPHSPSPIATPPSQSSSCSDAPMLS---TVHSAKNTPSQHSHSIQHSPERSGSGSV 277
               + +   P +  PS+  S S +   S    V   K        S + S  +S S S 
Sbjct: 276 KIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSR 335

Query: 278 GNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFL 337
             G SR   S++        +R   K    ++  R  SR +S      G +  +K G   
Sbjct: 336 SKGGSR---SRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSK 392

Query: 338 K 338
           K
Sbjct: 393 K 393



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 65/324 (20%), Positives = 113/324 (34%), Gaps = 46/324 (14%)

Query: 456 NERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRC 515
           + R  SY ++     +R +S    +    S S+   H++     R       K   + + 
Sbjct: 179 SRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQS 238

Query: 516 DSADLRHDIDRRRKERSKERGDSKG-SRESSGSRKQEK-------------TPKDYKEYK 561
            S   +       KE+S+ R  S G SR  S  + +EK             +P  +K   
Sbjct: 239 RSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKS 298

Query: 562 SYKDDSKHKREQDHSRSS-------------SSSASPSSPSSREEKESKKEREEEFKTHH 608
             +  S+ +R ++  R S             S S S S   SR    S+ + +++ K   
Sbjct: 299 KSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRK 358

Query: 609 EMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYTP 668
             +E S     SR R    R R RG  R   AG++           K+ K+E+ D   + 
Sbjct: 359 RSREES--RSRSRSRSKSERSRKRGSKRDSKAGSS-----------KKKKKEDTDRSQSR 405

Query: 669 KSKKYFLHDDRDDGVDYWAKRGRGR----GTFQ--RGRGRFNFKKSGSSPKWTHDKYQGD 722
              +    +      +   + GRG     GT Q  R R R N K   + P  +  + +  
Sbjct: 406 SPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSA 465

Query: 723 GIVEDEEETMENNEEKKDRRKEEK 746
                  ++   +  +   R   +
Sbjct: 466 SKTRSRSKSRSRSASRSPSRSRSR 489



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 74/368 (20%), Positives = 135/368 (36%), Gaps = 38/368 (10%)

Query: 265 IQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPD 324
           ++H+      GS G+G S Y   ++    + P  R+  + I    + R   +    +   
Sbjct: 67  VEHARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDLKDYMRQ 126

Query: 325 GGDQETAKTGKFLKSPPLHKNLD------AREKSTFREESPLRIKMIAS---DSHRPEVK 375
            G+   A   K  K+  + + +       A EK    E +  +I+++        R    
Sbjct: 127 AGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYS 186

Query: 376 LKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQH 435
              +       +R +  ++ R  +S   HS  + +         K    S+S S S  + 
Sbjct: 187 RSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEK 246

Query: 436 IVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHST----RQKSPEIHRRIDISPSTLRK 491
             S           SA  + ++     ++  + +      + +SP  H+         + 
Sbjct: 247 SRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKS--------KS 298

Query: 492 HTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRR---------KERSKERGDSKG-- 540
            +R   +ER  +EE +    + R     LR    R R         + RSK +   KG  
Sbjct: 299 KSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRK 358

Query: 541 -SRESSGSRKQEKTPKDYKEYKSYKDD-----SKHKREQDHSRSSSSSASPSSPSSREEK 594
            SRE S SR + ++  +    +  K D     SK K+++D  RS S S S S    RE  
Sbjct: 359 RSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHA 418

Query: 595 ESKKEREE 602
           +S+  + E
Sbjct: 419 KSESSQRE 426



 Score = 46.6 bits (109), Expect = 8e-05
 Identities = 52/231 (22%), Positives = 86/231 (37%), Gaps = 33/231 (14%)

Query: 505 ENQKGDKKLRCDSADLRHDIDRRRKERSKER----GDSKGSRESSGSRKQEKTPKDYKEY 560
           E++ G ++ R  S    H   R R   S++     G SK S   S SR +  +    K  
Sbjct: 174 EDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSR 233

Query: 561 KSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFK-------------TH 607
              +  S+ K+E+  S S   S S S  + +   +SK + EE+ +             + 
Sbjct: 234 SRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSR 293

Query: 608 HEMKEYSGFAGVSR-----PRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEW 662
           H+ K  S      R      RG+    RGR + + +    +   +   +  + R + +  
Sbjct: 294 HKSKSKSRSRSQERRVEEEKRGSV--SRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSK 351

Query: 663 DPEYTPKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPK 713
           D     K +K    + R         R R +    R RG     K+GSS K
Sbjct: 352 DKR---KGRKRSREESRS------RSRSRSKSERSRKRGSKRDSKAGSSKK 393



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 79/350 (22%), Positives = 133/350 (38%), Gaps = 54/350 (15%)

Query: 261 HSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSS 320
           +S S  HS  RS S       SR   S++S        RS +++       R +SR RS 
Sbjct: 185 YSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRS-------RSKSRSRS- 236

Query: 321 FYPDGGDQETAKTGKFLKSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAP 380
                  Q  +++ K     P      ++EKS  R  S  + +  + D    +++     
Sbjct: 237 -------QSRSRSKKEKSRSP------SKEKSRSRSHSAGKSRSKSKDQAEEKIQNN--- 280

Query: 381 VPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLV 440
              D+  +P S +  R  + +   S  +E+      +  K    S+  S+       SL 
Sbjct: 281 ---DNVGKPKSRSPSRHKSKSKSRSRSQERRV----EEEKRGSVSRGRSQE-----KSLR 328

Query: 441 HHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEER 500
                   K  + +   R  S  K+ ++   R++S E  R    S S   + +R  G +R
Sbjct: 329 QSRSRSRSKGGSRS---RSRSRSKSKDKRKGRKRSREESRSRSRSRSKSER-SRKRGSKR 384

Query: 501 VFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDS-----KGSRESSGSRKQEKT-- 553
             K  + K  KK   D +  R       KER   + +S     +G  E++G+ ++ ++  
Sbjct: 385 DSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRS 444

Query: 554 -------PKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKES 596
                  P    E +S    +   R +  SRS S+S SPS   SR    S
Sbjct: 445 RSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSRS 494



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 30/55 (54%), Positives = 37/55 (67%), Gaps = 8/55 (14%)

Query: 3   RSNSRSHS---SRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYS 54
           RSNS+S     S S+SRS+S+S++RSRS SR     SRS SR+ SRSRSR    S
Sbjct: 445 RSNSKSKPNLPSESRSRSKSASKTRSRSKSR-----SRSASRSPSRSRSRSHSRS 494


>gi|154146223 splicing factor, arginine/serine-rich 130 [Homo
           sapiens]
          Length = 805

 Score = 89.0 bits (219), Expect = 1e-17
 Identities = 95/284 (33%), Positives = 129/284 (45%), Gaps = 32/284 (11%)

Query: 4   SNSRSHSSRSKSRSQSSSRSRSRSHS--RKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDY 61
           S S + SS S S S  SSR+ SRS S  RKKR+S RSRS T    RSR R YSR  R   
Sbjct: 526 STSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHS-RSRSPTIKARRSRSRSYSR--RIKI 582

Query: 62  RNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSP--RRGRSRSRSPKRRS 119
            +NR   +    R   R   +                RR +RSP   R RSRSRS  RR+
Sbjct: 583 ESNRARVKIRDRRRSNRNSIER--------------ERRRNRSPSRERRRSRSRSRDRRT 628

Query: 120 VSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQ--EKQTKKAEGE-PQEE 176
             + RSRSR RR     R   S +S      +K    K+  S+  +K  KK + E  +E+
Sbjct: 629 NRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQ 688

Query: 177 SPLKSKSQEEPKD---TFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIA 233
              K K + E KD   + + D  +   E  ++ + SG I   +  +D+   S  S +  +
Sbjct: 689 DKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDS 748

Query: 234 TPPSQSS----SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSG 273
              S S     S S++P  S    AK      S S++ S +RSG
Sbjct: 749 KKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKS-QRSG 791



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 45/170 (26%), Positives = 74/170 (43%), Gaps = 18/170 (10%)

Query: 451 AAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAG----EERVFKEEN 506
           A + + +R  S + + E    R +SP   RR   S S  R+  R +     + R   ++ 
Sbjct: 587 ARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQR 646

Query: 507 ---------QKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDY 557
                     KG+ K +    +    ID+ RK++ KER   +  R+     KQ++  KD+
Sbjct: 647 GNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKE----KQKREEKDF 702

Query: 558 KEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH 607
           K + S  D  K KRE + + S S S S         ++SKK   ++ K H
Sbjct: 703 K-FSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKH 751



 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 115/578 (19%), Positives = 209/578 (36%), Gaps = 86/578 (14%)

Query: 60  DYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRS------- 112
           DY++      P G  G    Y+Q G      G   P  NRR   S  R R RS       
Sbjct: 165 DYQHGAAFGPPQG--GFHPPYWQPGPP----GPPAPPQNRRERPSSFRDRQRSPIALPVK 218

Query: 113 RSPKRRSVSSQRSRSRSRRS--YRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAE 170
           + P +     +R+     R    +  R  +    +      +S +SK+   ++K T+ AE
Sbjct: 219 QEPPQIDAVKRRTLPAWIREGLEKMEREKQKKLEKERMEQQRSQLSKK---EKKATEDAE 275

Query: 171 GEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPS 230
           G      P +SK        F+ D  E  D  N  +A+SG +    S     P+  HS  
Sbjct: 276 GGDGPRLPQRSK--------FDSDEEEE-DTENVEAASSGKVTRSPSPV---PQEEHSDP 323

Query: 231 PIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNS 290
            +     +        ML T      T  +  +  + +                      
Sbjct: 324 EMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKDA---------------------- 361

Query: 291 PIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKSPP-----LHKN 345
              H  + ++PAK +A  +A    +          GD E  ++ +  +S       L   
Sbjct: 362 ---HRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHR 418

Query: 346 LDAREKSTFREESPLRI---KMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTL 402
           +  ++++ +R+E   ++   K +  +  + E   K     +       SL + R     +
Sbjct: 419 IRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDV 478

Query: 403 VHSVKKE-QEFRSIFD----HIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNE 457
           V+  K+   E  S+ +    H +  +  +S S S      S           S + T++ 
Sbjct: 479 VNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSS-----SNSRTSSTSSTVSS 533

Query: 458 RFTSYQKATEEHSTRQKSPEIHRRIDIS--PSTLRKHTRLAGEERVFKEENQKGDKKLRC 515
              S    +   S+R  SP+  +R   S  P+   + +R     R  K E+ +   K+R 
Sbjct: 534 SSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIR- 592

Query: 516 DSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKT-PKDYKEYKSYKDDSKHKREQD 574
                    DRRR  R+    + + +R  S  R++ ++  +D +  ++ +  S+ +R+ D
Sbjct: 593 ---------DRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKID 643

Query: 575 HSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKE 612
             R + S  S       +E+E KKER        + K+
Sbjct: 644 DQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKD 681



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 38/168 (22%), Positives = 74/168 (44%), Gaps = 15/168 (8%)

Query: 2   GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDY 61
           G  +  SH  + +++ Q   + RSRS  + ++   + R R   + + + +   +D++   
Sbjct: 647 GNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSS 706

Query: 62  RNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRR--S 119
           +++R  R+    R             + R G   V   RH       +S ++  K+   S
Sbjct: 707 QDDRLKRKRESER------------TFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGS 754

Query: 120 VSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTK 167
            SS RS S S  S +  ++ +   SRS S   KS  S ++ S++ ++K
Sbjct: 755 DSSGRSSSESPGSSKEKKAKKPKHSRSRS-VEKSQRSGKKASRKHKSK 801



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 53/226 (23%), Positives = 85/226 (37%), Gaps = 19/226 (8%)

Query: 541 SRESSGSRKQEK--TPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKK 598
           +RE+ G    EK  TP +       K + K K +Q  SRS SSS+  SS +SR    S  
Sbjct: 471 AREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSST 530

Query: 599 EREEEFKTHHEMKEYSGFAGV-------SRPRGTFF---RIRGRGRARGVFAGTNTG--- 645
                + +       S  +         SR R       R R R  +R +   +N     
Sbjct: 531 VSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVK 590

Query: 646 ---PNNSNTTFQKRPKEEEWDPEYTPKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGR 702
                 SN    +R +     P    +  +    D R +       R R +   QRG   
Sbjct: 591 IRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLS 650

Query: 703 FN-FKKSGSSPKWTHDKYQGDGIVEDEEETMENNEEKKDRRKEEKE 747
            N  K  G + +    K +   I +D ++  +  E ++D+RKE+++
Sbjct: 651 GNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQK 696



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 52/209 (24%), Positives = 81/209 (38%), Gaps = 23/209 (11%)

Query: 3   RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYR 62
           R++      R++S S+   RSRSRS  R        R+   SRSRSRDR    D R +  
Sbjct: 599 RNSIERERRRNRSPSRERRRSRSRSRDR--------RTNRASRSRSRDRRKIDDQRGNLS 650

Query: 63  NNRGMRRPYGYRGRGRGYYQGGGGRYHRG---GYRPVWNRRHSRSPRRGRSRSRSPKRRS 119
            N        ++ +G    Q       R      +     R     +R   + R  K   
Sbjct: 651 GN-------SHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFK 703

Query: 120 VSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKR---RGSQEKQTKKAEGEPQEE 176
            SSQ  R + +R    + S   S S     +     SK+   + S++     + G    E
Sbjct: 704 FSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSE 763

Query: 177 SPLKSKSQEEPKDTFEHDPSESIDEFNKS 205
           SP  SK ++  K   +H  S S+++  +S
Sbjct: 764 SPGSSKEKKAKKP--KHSRSRSVEKSQRS 790



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 39/154 (25%), Positives = 72/154 (46%), Gaps = 18/154 (11%)

Query: 470 STRQKSPEIHRRIDISPSTL----RKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDID 525
           ++R +S +  R+ID     L     KH   A E+   KE ++  DK  +    +   + D
Sbjct: 631 ASRSRSRD-RRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQD 689

Query: 526 RRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSY---------KDDSKHKREQD-- 574
           +R++++ +E  D K S +    +++ ++ + +    S          + DSK    +D  
Sbjct: 690 KRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSK 749

Query: 575 -HSRSSSSSASPS-SPSSREEKESKKEREEEFKT 606
            HS S SS  S S SP S +EK++KK +    ++
Sbjct: 750 KHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRS 783



 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 103/473 (21%), Positives = 160/473 (33%), Gaps = 63/473 (13%)

Query: 133 YRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFE 192
           Y S  S    S R S          R   ++KQ      E +E+  L  K  EE K   E
Sbjct: 391 YGSGDSEDERSDRGSESSDTDDEELRHRIRQKQEAFWRKE-KEQQLLHDKQMEEEKQQTE 449

Query: 193 HDPSESIDEFNKSSATSGDIWPGLSA----YDNSPRSPHSPSPIATPPSQSSSCSDAPML 248
               E ++EF      S  +     A     +   R+P+  + +  P  +          
Sbjct: 450 RVTKE-MNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRS 508

Query: 249 STVHSAKNTPSQHSH-SIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAP 307
            +  S+  + S +S  S   S   S S S  +GSSR S   +SP       RS + TI  
Sbjct: 509 RSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTI-- 566

Query: 308 QNAPRDESRGRSSFYPDGGDQETAKTGKFLKSPPLHKNLDAREKSTFREESPLRIKMIAS 367
             A R  SR  S       ++   K     +S     N ++ E+   R  SP R      
Sbjct: 567 -KARRSRSRSYSRRIKIESNRARVKIRDRRRS-----NRNSIERERRRNRSPSR------ 614

Query: 368 DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS 427
                            +  R  S ++DR    T   S  + ++ R I D     Q    
Sbjct: 615 -----------------ERRRSRSRSRDR---RTNRASRSRSRDRRKIDD-----QRGNL 649

Query: 428 TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS 487
           +  S      +     K++  +S      ++    ++  ++   +QK  E   +      
Sbjct: 650 SGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDD 709

Query: 488 TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS 547
            L++       ER F        K +R       HD  +  K +S  +   K S   S  
Sbjct: 710 RLKRKRE---SERTFSRSGSISVKIIR-------HDSRQDSK-KSTTKDSKKHSGSDSSG 758

Query: 548 RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKER 600
           R   ++P   KE K+ K   KH R    SRS   S      +SR+ K   + R
Sbjct: 759 RSSSESPGSSKEKKAKK--PKHSR----SRSVEKSQRSGKKASRKHKSKSRSR 805



 Score = 34.3 bits (77), Expect = 0.43
 Identities = 17/48 (35%), Positives = 28/48 (58%)

Query: 2   GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSR 49
           GRS+S S  S  + +++    SRSRS  + +R   ++  +  S+SRSR
Sbjct: 758 GRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKSRSR 805



 Score = 31.6 bits (70), Expect = 2.8
 Identities = 19/59 (32%), Positives = 31/59 (52%), Gaps = 1/59 (1%)

Query: 5   NSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRN 63
           +S+ HS  S S  +SSS S   S  +K +    SRSR+  +S+   +  SR ++   R+
Sbjct: 747 DSKKHSG-SDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKSRS 804


>gi|154146193 splicing factor, arginine/serine-rich 130 [Homo
           sapiens]
          Length = 805

 Score = 89.0 bits (219), Expect = 1e-17
 Identities = 95/284 (33%), Positives = 129/284 (45%), Gaps = 32/284 (11%)

Query: 4   SNSRSHSSRSKSRSQSSSRSRSRSHS--RKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDY 61
           S S + SS S S S  SSR+ SRS S  RKKR+S RSRS T    RSR R YSR  R   
Sbjct: 526 STSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHS-RSRSPTIKARRSRSRSYSR--RIKI 582

Query: 62  RNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSP--RRGRSRSRSPKRRS 119
            +NR   +    R   R   +                RR +RSP   R RSRSRS  RR+
Sbjct: 583 ESNRARVKIRDRRRSNRNSIER--------------ERRRNRSPSRERRRSRSRSRDRRT 628

Query: 120 VSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQ--EKQTKKAEGE-PQEE 176
             + RSRSR RR     R   S +S      +K    K+  S+  +K  KK + E  +E+
Sbjct: 629 NRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQ 688

Query: 177 SPLKSKSQEEPKD---TFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIA 233
              K K + E KD   + + D  +   E  ++ + SG I   +  +D+   S  S +  +
Sbjct: 689 DKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDS 748

Query: 234 TPPSQSS----SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSG 273
              S S     S S++P  S    AK      S S++ S +RSG
Sbjct: 749 KKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKS-QRSG 791



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 45/170 (26%), Positives = 74/170 (43%), Gaps = 18/170 (10%)

Query: 451 AAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAG----EERVFKEEN 506
           A + + +R  S + + E    R +SP   RR   S S  R+  R +     + R   ++ 
Sbjct: 587 ARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQR 646

Query: 507 ---------QKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDY 557
                     KG+ K +    +    ID+ RK++ KER   +  R+     KQ++  KD+
Sbjct: 647 GNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKE----KQKREEKDF 702

Query: 558 KEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH 607
           K + S  D  K KRE + + S S S S         ++SKK   ++ K H
Sbjct: 703 K-FSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKH 751



 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 115/578 (19%), Positives = 209/578 (36%), Gaps = 86/578 (14%)

Query: 60  DYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRS------- 112
           DY++      P G  G    Y+Q G      G   P  NRR   S  R R RS       
Sbjct: 165 DYQHGAAFGPPQG--GFHPPYWQPGPP----GPPAPPQNRRERPSSFRDRQRSPIALPVK 218

Query: 113 RSPKRRSVSSQRSRSRSRRS--YRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAE 170
           + P +     +R+     R    +  R  +    +      +S +SK+   ++K T+ AE
Sbjct: 219 QEPPQIDAVKRRTLPAWIREGLEKMEREKQKKLEKERMEQQRSQLSKK---EKKATEDAE 275

Query: 171 GEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPS 230
           G      P +SK        F+ D  E  D  N  +A+SG +    S     P+  HS  
Sbjct: 276 GGDGPRLPQRSK--------FDSDEEEE-DTENVEAASSGKVTRSPSPV---PQEEHSDP 323

Query: 231 PIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNS 290
            +     +        ML T      T  +  +  + +                      
Sbjct: 324 EMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKDA---------------------- 361

Query: 291 PIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKSPP-----LHKN 345
              H  + ++PAK +A  +A    +          GD E  ++ +  +S       L   
Sbjct: 362 ---HRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHR 418

Query: 346 LDAREKSTFREESPLRI---KMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTL 402
           +  ++++ +R+E   ++   K +  +  + E   K     +       SL + R     +
Sbjct: 419 IRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDV 478

Query: 403 VHSVKKE-QEFRSIFD----HIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNE 457
           V+  K+   E  S+ +    H +  +  +S S S      S           S + T++ 
Sbjct: 479 VNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSS-----SNSRTSSTSSTVSS 533

Query: 458 RFTSYQKATEEHSTRQKSPEIHRRIDIS--PSTLRKHTRLAGEERVFKEENQKGDKKLRC 515
              S    +   S+R  SP+  +R   S  P+   + +R     R  K E+ +   K+R 
Sbjct: 534 SSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIR- 592

Query: 516 DSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKT-PKDYKEYKSYKDDSKHKREQD 574
                    DRRR  R+    + + +R  S  R++ ++  +D +  ++ +  S+ +R+ D
Sbjct: 593 ---------DRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKID 643

Query: 575 HSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKE 612
             R + S  S       +E+E KKER        + K+
Sbjct: 644 DQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKD 681



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 38/168 (22%), Positives = 74/168 (44%), Gaps = 15/168 (8%)

Query: 2   GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDY 61
           G  +  SH  + +++ Q   + RSRS  + ++   + R R   + + + +   +D++   
Sbjct: 647 GNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSS 706

Query: 62  RNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRR--S 119
           +++R  R+    R             + R G   V   RH       +S ++  K+   S
Sbjct: 707 QDDRLKRKRESER------------TFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGS 754

Query: 120 VSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTK 167
            SS RS S S  S +  ++ +   SRS S   KS  S ++ S++ ++K
Sbjct: 755 DSSGRSSSESPGSSKEKKAKKPKHSRSRS-VEKSQRSGKKASRKHKSK 801



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 53/226 (23%), Positives = 85/226 (37%), Gaps = 19/226 (8%)

Query: 541 SRESSGSRKQEK--TPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKK 598
           +RE+ G    EK  TP +       K + K K +Q  SRS SSS+  SS +SR    S  
Sbjct: 471 AREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSST 530

Query: 599 EREEEFKTHHEMKEYSGFAGV-------SRPRGTFF---RIRGRGRARGVFAGTNTG--- 645
                + +       S  +         SR R       R R R  +R +   +N     
Sbjct: 531 VSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVK 590

Query: 646 ---PNNSNTTFQKRPKEEEWDPEYTPKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGR 702
                 SN    +R +     P    +  +    D R +       R R +   QRG   
Sbjct: 591 IRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLS 650

Query: 703 FN-FKKSGSSPKWTHDKYQGDGIVEDEEETMENNEEKKDRRKEEKE 747
            N  K  G + +    K +   I +D ++  +  E ++D+RKE+++
Sbjct: 651 GNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQK 696



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 52/209 (24%), Positives = 81/209 (38%), Gaps = 23/209 (11%)

Query: 3   RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYR 62
           R++      R++S S+   RSRSRS  R        R+   SRSRSRDR    D R +  
Sbjct: 599 RNSIERERRRNRSPSRERRRSRSRSRDR--------RTNRASRSRSRDRRKIDDQRGNLS 650

Query: 63  NNRGMRRPYGYRGRGRGYYQGGGGRYHRG---GYRPVWNRRHSRSPRRGRSRSRSPKRRS 119
            N        ++ +G    Q       R      +     R     +R   + R  K   
Sbjct: 651 GN-------SHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFK 703

Query: 120 VSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKR---RGSQEKQTKKAEGEPQEE 176
            SSQ  R + +R    + S   S S     +     SK+   + S++     + G    E
Sbjct: 704 FSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSE 763

Query: 177 SPLKSKSQEEPKDTFEHDPSESIDEFNKS 205
           SP  SK ++  K   +H  S S+++  +S
Sbjct: 764 SPGSSKEKKAKKP--KHSRSRSVEKSQRS 790



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 39/154 (25%), Positives = 72/154 (46%), Gaps = 18/154 (11%)

Query: 470 STRQKSPEIHRRIDISPSTL----RKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDID 525
           ++R +S +  R+ID     L     KH   A E+   KE ++  DK  +    +   + D
Sbjct: 631 ASRSRSRD-RRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQD 689

Query: 526 RRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSY---------KDDSKHKREQD-- 574
           +R++++ +E  D K S +    +++ ++ + +    S          + DSK    +D  
Sbjct: 690 KRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSK 749

Query: 575 -HSRSSSSSASPS-SPSSREEKESKKEREEEFKT 606
            HS S SS  S S SP S +EK++KK +    ++
Sbjct: 750 KHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRS 783



 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 103/473 (21%), Positives = 160/473 (33%), Gaps = 63/473 (13%)

Query: 133 YRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFE 192
           Y S  S    S R S          R   ++KQ      E +E+  L  K  EE K   E
Sbjct: 391 YGSGDSEDERSDRGSESSDTDDEELRHRIRQKQEAFWRKE-KEQQLLHDKQMEEEKQQTE 449

Query: 193 HDPSESIDEFNKSSATSGDIWPGLSA----YDNSPRSPHSPSPIATPPSQSSSCSDAPML 248
               E ++EF      S  +     A     +   R+P+  + +  P  +          
Sbjct: 450 RVTKE-MNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRS 508

Query: 249 STVHSAKNTPSQHSH-SIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAP 307
            +  S+  + S +S  S   S   S S S  +GSSR S   +SP       RS + TI  
Sbjct: 509 RSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTI-- 566

Query: 308 QNAPRDESRGRSSFYPDGGDQETAKTGKFLKSPPLHKNLDAREKSTFREESPLRIKMIAS 367
             A R  SR  S       ++   K     +S     N ++ E+   R  SP R      
Sbjct: 567 -KARRSRSRSYSRRIKIESNRARVKIRDRRRS-----NRNSIERERRRNRSPSR------ 614

Query: 368 DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS 427
                            +  R  S ++DR    T   S  + ++ R I D     Q    
Sbjct: 615 -----------------ERRRSRSRSRDR---RTNRASRSRSRDRRKIDD-----QRGNL 649

Query: 428 TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS 487
           +  S      +     K++  +S      ++    ++  ++   +QK  E   +      
Sbjct: 650 SGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDD 709

Query: 488 TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS 547
            L++       ER F        K +R       HD  +  K +S  +   K S   S  
Sbjct: 710 RLKRKRE---SERTFSRSGSISVKIIR-------HDSRQDSK-KSTTKDSKKHSGSDSSG 758

Query: 548 RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKER 600
           R   ++P   KE K+ K   KH R    SRS   S      +SR+ K   + R
Sbjct: 759 RSSSESPGSSKEKKAKK--PKHSR----SRSVEKSQRSGKKASRKHKSKSRSR 805



 Score = 34.3 bits (77), Expect = 0.43
 Identities = 17/48 (35%), Positives = 28/48 (58%)

Query: 2   GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSR 49
           GRS+S S  S  + +++    SRSRS  + +R   ++  +  S+SRSR
Sbjct: 758 GRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKSRSR 805



 Score = 31.6 bits (70), Expect = 2.8
 Identities = 19/59 (32%), Positives = 31/59 (52%), Gaps = 1/59 (1%)

Query: 5   NSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRN 63
           +S+ HS  S S  +SSS S   S  +K +    SRSR+  +S+   +  SR ++   R+
Sbjct: 747 DSKKHSG-SDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKSRS 804


>gi|133922600 splicing factor, arginine/serine-rich 16 [Homo
           sapiens]
          Length = 674

 Score = 88.6 bits (218), Expect = 2e-17
 Identities = 85/224 (37%), Positives = 105/224 (46%), Gaps = 37/224 (16%)

Query: 3   RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKR----YSS----RSRSRTYSRSRSRDRMYS 54
           R +S S SS S SR+ SSSRS SRS SR +R    Y S    RSRSR++SRSRSR R YS
Sbjct: 375 RRSSSSSSSSSASRT-SSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYS 433

Query: 55  RDYRRDYRNNRG-------------MRRPYGYRGRGRGYYQGGGGRYHRGG--------- 92
           R   R  R++ G              R  YG R R R      G RY RGG         
Sbjct: 434 RSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRS-RSHSGDRYRRGGRGLRHHSSS 492

Query: 93  -YRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSR-SSSPY 150
             R  W+   SRS    RSRS SP   S S  RSRSRSR    S    R   +R ++SP 
Sbjct: 493 RSRSSWSLSPSRSRSLTRSRSHSP---SPSQSRSRSRSRSQSPSPSPAREKLTRPAASPA 549

Query: 151 SKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHD 194
               + K   +  K+T  A+ +   +  LK + Q+     F+ D
Sbjct: 550 VGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKAD 593



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 108/487 (22%), Positives = 187/487 (38%), Gaps = 84/487 (17%)

Query: 110 SRSRSPKRRSVSSQRSRSRSRRSYRSSR------SPRSSSSRSSSPYSKSPVSKRRGSQE 163
           +++   ++   S +RSR R RR +R  R      SP S + R S  Y     S    S E
Sbjct: 252 AKALEEEKAMYSGRRSR-RQRREFREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSSE 310

Query: 164 KQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSP 223
            +++     P  E           K TF      S DE   ++A +       +    +P
Sbjct: 311 SRSRSRSPTPGREE----------KITFITSFGGS-DEEAAAAAAAAAASGVTTGKPPAP 359

Query: 224 RSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSR 283
             P  P+P     ++  S S     S+  SA  T S  S S   S  R G G   +G   
Sbjct: 360 PQPGGPAPGRNASARRRSSSS----SSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHA 415

Query: 284 YSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKSPPLH 343
            S S++       SRR            R  SRGR   +  GG ++  +   + +SP   
Sbjct: 416 RSRSRSWSRSRSRSRRYS----------RSRSRGRR--HSGGGSRDGHR---YSRSPARR 460

Query: 344 KNLDAREKSTFREESPLRIK-----MIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLL 398
                R +S  R  S  R +     +    S R      ++P      +R  SLT+ R  
Sbjct: 461 GGYGPRRRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSP------SRSRSLTRSR-- 512

Query: 399 ASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAM-TLNE 457
                              H   P  S+S S S  Q         +E+  + AA   + E
Sbjct: 513 ------------------SHSPSPSQSRSRSRSRSQS--PSPSPAREKLTRPAASPAVGE 552

Query: 458 RFTSYQKATEEHSTRQK---SPEIHRRIDISPSTLR--KHTRLAGEERVFKEENQKGDKK 512
           +    + A  + +   K   +P+   ++ +  +  R  K  + A +E++ ++E+++ +++
Sbjct: 553 KLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQERE 612

Query: 513 --LRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHK 570
             LR  +  +R   +R R+E+ +E  + + SR+S     +  +P+  +EY S +  S+ +
Sbjct: 613 DELRAMARKIRMK-ERERREKEREEWERQYSRQS-----RSPSPRYSREYSSSRRRSRSR 666

Query: 571 REQDHSR 577
               H R
Sbjct: 667 SRSPHYR 673



 Score = 39.7 bits (91), Expect = 0.010
 Identities = 49/182 (26%), Positives = 68/182 (37%), Gaps = 35/182 (19%)

Query: 4   SNSRSHSSRSKSRSQSSSRSRSRSHS---RKKRYSSRSRSRTYSRSRSRDRM-------- 52
           S+SRS SS S S S+S S +RSRSHS    + R  SRSRS++ S S +R+++        
Sbjct: 490 SSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASPA 549

Query: 53  ----------------------YSRDYRRDYRNNRGMRRPY--GYRGRGRGYYQGGGGRY 88
                                  +   +   R  + + R +    +       Q    R 
Sbjct: 550 VGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQ 609

Query: 89  HRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSS 148
            R        R+     R  R + R    R  S Q      R S   S S R S SRS S
Sbjct: 610 EREDELRAMARKIRMKERERREKEREEWERQYSRQSRSPSPRYSREYSSSRRRSRSRSRS 669

Query: 149 PY 150
           P+
Sbjct: 670 PH 671



 Score = 32.0 bits (71), Expect = 2.2
 Identities = 18/53 (33%), Positives = 25/53 (47%)

Query: 3   RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSR 55
           R+ +R    + + R +       R +SR+ R  S   SR YS SR R R  SR
Sbjct: 616 RAMARKIRMKERERREKEREEWERQYSRQSRSPSPRYSREYSSSRRRSRSRSR 668



 Score = 30.0 bits (66), Expect = 8.2
 Identities = 35/139 (25%), Positives = 51/139 (36%), Gaps = 11/139 (7%)

Query: 459 FTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEE--RVFKEENQKGDKKLRCD 516
           + S + A     +  +S    RR   S S  R+H+     +  R  +   ++G    R  
Sbjct: 409 YRSGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRR 468

Query: 517 SADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKRE--QD 574
           S    H  DR R+         +G R  S SR +          +S      H     Q 
Sbjct: 469 SRSRSHSGDRYRR-------GGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQS 521

Query: 575 HSRSSSSSASPSSPSSREE 593
            SRS S S SPS   +RE+
Sbjct: 522 RSRSRSRSQSPSPSPAREK 540


>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
           [Homo sapiens]
          Length = 624

 Score = 85.5 bits (210), Expect = 2e-16
 Identities = 89/334 (26%), Positives = 135/334 (40%), Gaps = 52/334 (15%)

Query: 2   GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDY 61
           G+SN R    RS+S ++S SRS S+SHSR+KR  S+ RSR+++RSRSR            
Sbjct: 298 GKSNERK-GGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQ----------- 345

Query: 62  RNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVS 121
           ++ R  + P+  R + R               R   +R HSR  R+        K R   
Sbjct: 346 KDRRRSKSPHKKRSKSR-------------ERRKSRSRSHSRDKRKDTREKIKEKERVKE 392

Query: 122 SQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKS 181
             R + R R   R     R  +        K     +   +E++ +K   + +++   K 
Sbjct: 393 KDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKE--KE 450

Query: 182 KSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSS 241
           K Q++ K+  E D S+ IDE  K    S    P  S Y+ S RS  S        S+SSS
Sbjct: 451 KEQDKEKER-EKDRSKEIDEKRKKDKKSRT--PPRS-YNASRRSRSSSRERRRRRSRSSS 506

Query: 242 CSDAPMLSTVHSAKNTPSQHSHS------------IQHSPERSGSGSVGNGSS------- 282
            S     +    +  +PS  S +            I    ER  S S+   S+       
Sbjct: 507 RSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEK 566

Query: 283 --RYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDE 314
             + S S     H+     S +K +  ++APR E
Sbjct: 567 LEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTE 600



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 67/297 (22%), Positives = 115/297 (38%), Gaps = 30/297 (10%)

Query: 463 QKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRH 522
           + +++ HS R++S   HR    + S  R+  R   +    K    +  +K R  S     
Sbjct: 317 RSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDK 376

Query: 523 DIDRRRKERSKER---GDSKGSRESSGSRKQEK---------TPKDYKEYKSYKDDSKHK 570
             D R K + KER    D +  RE    R++EK           ++    K  + D + +
Sbjct: 377 RKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERE 436

Query: 571 REQDHSRSSSSSASPSSPSSRE-EKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFFRI 629
           RE++H +             +E EK+  KE +E+ K   + +        SR   +  R 
Sbjct: 437 REKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRE 496

Query: 630 RGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYTPKSKKYFLHDDRDDGVDYWAKR 689
           R R R+R     ++  P  S T  +K  +     P    ++KK    +   D +    +R
Sbjct: 497 RRRRRSR----SSSRSPRTSKTIKRKSSR----SPSPRSRNKKDKKREKERDHIS--ERR 546

Query: 690 GRGRGTFQRGR-----GRFNFKKSGSSPKWTHDKYQGDGIV--EDEEETMENNEEKK 739
            R R T  R       G+   +K+ +S K      + D  V  E +++     EE K
Sbjct: 547 ERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENK 603



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 60/267 (22%), Positives = 101/267 (37%), Gaps = 15/267 (5%)

Query: 348 AREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVK 407
           + E+   R  S  R K  +S       K   +       NR  S  KDR  + +      
Sbjct: 300 SNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRS 359

Query: 408 KEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATE 467
           K +E R            K T E   +        VKE+  +       ER    +K   
Sbjct: 360 KSRERRKSRSRSHSRDKRKDTREKIKEK-----ERVKEKDREKEREREKER--EKEKERG 412

Query: 468 EHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRR 527
           ++  R K  E  R  D      R+  +   ++R  ++E ++  +K R    D   +ID +
Sbjct: 413 KNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKER--EKDRSKEIDEK 470

Query: 528 RKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSS 587
           RK+  K R      R  + SR+   + ++ +  +S       +  +   R SS S    S
Sbjct: 471 RKKDKKSR---TPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRS---PS 524

Query: 588 PSSREEKESKKEREEEFKTHHEMKEYS 614
           P SR +K+ K+E+E +  +    +E S
Sbjct: 525 PRSRNKKDKKREKERDHISERRERERS 551



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 34/122 (27%), Positives = 53/122 (43%), Gaps = 5/122 (4%)

Query: 95  PVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSP 154
           P   + + R   R RS +RS  R S  S   R RS+  +RS    RS S +     SKSP
Sbjct: 295 PESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSP 354

Query: 155 VSKRRGSQEKQTKKAEGEPQEE-----SPLKSKSQEEPKDTFEHDPSESIDEFNKSSATS 209
             KR  S+E++  ++    +++       +K K + + KD  +    E   E  K    +
Sbjct: 355 HKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKN 414

Query: 210 GD 211
            D
Sbjct: 415 KD 416



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 83/402 (20%), Positives = 153/402 (38%), Gaps = 46/402 (11%)

Query: 215 GLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGS 274
           G+   D   +  HS + I  PP  +   +   +   +   +   S  S +I+  PE   S
Sbjct: 243 GVMFGDRPLKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIE--PESGKS 300

Query: 275 GSVGNGSSRY---SPSQNSPIHHIPSRRSPAKTIA-----PQNAPRDESRGRSSFYPDGG 326
                G SR    S S++S   H   +RS +K  +      ++  +D  R +S       
Sbjct: 301 NERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSK 360

Query: 327 DQETAKTGKFLKSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDS 386
            +E  K+    +S    K  D REK   +E+  ++ K    +  R + + K       + 
Sbjct: 361 SRERRKSRS--RSHSRDKRKDTREK--IKEKERVKEKDREKEREREKEREK-------EK 409

Query: 387 NRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQ 446
            R  +  +D+          +K++E     +H K     K   +             +++
Sbjct: 410 ERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQD-----------KEKE 458

Query: 447 YFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEEN 506
             K  +  ++E+    +K  ++  T  +S    RR   S S  R+  R     R  +   
Sbjct: 459 REKDRSKEIDEK----RKKDKKSRTPPRSYNASRR-SRSSSRERRRRRSRSSSRSPRTSK 513

Query: 507 QKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDD 566
               K  R  S   R+  D++R E+ ++    +  RE S S ++    +D KE    + +
Sbjct: 514 TIKRKSSRSPSPRSRNKKDKKR-EKERDHISERRERERSTSMRKSSNDRDGKE--KLEKN 570

Query: 567 SKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHH 608
           S   +E++H++       P S  S+E  +    R EE K  H
Sbjct: 571 STSLKEKEHNKE------PDSSVSKEVDDKDAPRTEENKIQH 606



 Score = 37.4 bits (85), Expect = 0.051
 Identities = 50/211 (23%), Positives = 80/211 (37%), Gaps = 37/211 (17%)

Query: 537 DSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKES 596
           +S  S E  G R +  T    K   S K  S+ KR Q   RS S + S S    ++ + S
Sbjct: 296 ESGKSNERKGGRSRSHTRS--KSRSSSKSHSRRKRSQSKHRSRSHNRSRS--RQKDRRRS 351

Query: 597 KKEREEEFKTHHEMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKR 656
           K   ++  K+    K  S      + + T  +I+ + R +                 + R
Sbjct: 352 KSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKE----------------KDR 395

Query: 657 PKEEEWDPEYTPKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTH 716
            KE E + E   K K+   + DRD                +R + R   K+     +   
Sbjct: 396 EKEREREKE-REKEKERGKNKDRDK---------------EREKDREKDKEK-DRERERE 438

Query: 717 DKYQGDGIVEDEEETMENNEEKKDRRKEEKE 747
            +++ D   E E+E  +  E +KDR KE  E
Sbjct: 439 KEHEKDRDKEKEKEQDKEKEREKDRSKEIDE 469



 Score = 35.4 bits (80), Expect = 0.19
 Identities = 35/152 (23%), Positives = 57/152 (37%), Gaps = 20/152 (13%)

Query: 464 KATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHD 523
           K  EE   R +  +      I P + + + R  G  R       +   K           
Sbjct: 273 KELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSH--------- 323

Query: 524 IDRRRKERSKERGDSKG-SRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSS 582
             RR++ +SK R  S   SR     R++ K+P         K     +R +  SRS S  
Sbjct: 324 -SRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHK-------KRSKSRERRKSRSRSHSRD 375

Query: 583 ASPSSPSSREEKE--SKKEREEEFKTHHEMKE 612
               +    +EKE   +K+RE+E +   E ++
Sbjct: 376 KRKDTREKIKEKERVKEKDREKEREREKEREK 407


>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
           [Homo sapiens]
          Length = 508

 Score = 85.5 bits (210), Expect = 2e-16
 Identities = 89/334 (26%), Positives = 135/334 (40%), Gaps = 52/334 (15%)

Query: 2   GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDY 61
           G+SN R    RS+S ++S SRS S+SHSR+KR  S+ RSR+++RSRSR            
Sbjct: 182 GKSNERK-GGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQ----------- 229

Query: 62  RNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVS 121
           ++ R  + P+  R + R               R   +R HSR  R+        K R   
Sbjct: 230 KDRRRSKSPHKKRSKSR-------------ERRKSRSRSHSRDKRKDTREKIKEKERVKE 276

Query: 122 SQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKS 181
             R + R R   R     R  +        K     +   +E++ +K   + +++   K 
Sbjct: 277 KDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKE--KE 334

Query: 182 KSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSS 241
           K Q++ K+  E D S+ IDE  K    S    P  S Y+ S RS  S        S+SSS
Sbjct: 335 KEQDKEKER-EKDRSKEIDEKRKKDKKSRT--PPRS-YNASRRSRSSSRERRRRRSRSSS 390

Query: 242 CSDAPMLSTVHSAKNTPSQHSHS------------IQHSPERSGSGSVGNGSS------- 282
            S     +    +  +PS  S +            I    ER  S S+   S+       
Sbjct: 391 RSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEK 450

Query: 283 --RYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDE 314
             + S S     H+     S +K +  ++APR E
Sbjct: 451 LEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTE 484



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 67/297 (22%), Positives = 115/297 (38%), Gaps = 30/297 (10%)

Query: 463 QKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRH 522
           + +++ HS R++S   HR    + S  R+  R   +    K    +  +K R  S     
Sbjct: 201 RSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDK 260

Query: 523 DIDRRRKERSKER---GDSKGSRESSGSRKQEK---------TPKDYKEYKSYKDDSKHK 570
             D R K + KER    D +  RE    R++EK           ++    K  + D + +
Sbjct: 261 RKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERE 320

Query: 571 REQDHSRSSSSSASPSSPSSRE-EKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFFRI 629
           RE++H +             +E EK+  KE +E+ K   + +        SR   +  R 
Sbjct: 321 REKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRE 380

Query: 630 RGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYTPKSKKYFLHDDRDDGVDYWAKR 689
           R R R+R     ++  P  S T  +K  +     P    ++KK    +   D +    +R
Sbjct: 381 RRRRRSR----SSSRSPRTSKTIKRKSSR----SPSPRSRNKKDKKREKERDHIS--ERR 430

Query: 690 GRGRGTFQRGR-----GRFNFKKSGSSPKWTHDKYQGDGIV--EDEEETMENNEEKK 739
            R R T  R       G+   +K+ +S K      + D  V  E +++     EE K
Sbjct: 431 ERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENK 487



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 60/267 (22%), Positives = 101/267 (37%), Gaps = 15/267 (5%)

Query: 348 AREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVK 407
           + E+   R  S  R K  +S       K   +       NR  S  KDR  + +      
Sbjct: 184 SNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRS 243

Query: 408 KEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATE 467
           K +E R            K T E   +        VKE+  +       ER    +K   
Sbjct: 244 KSRERRKSRSRSHSRDKRKDTREKIKEK-----ERVKEKDREKEREREKER--EKEKERG 296

Query: 468 EHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRR 527
           ++  R K  E  R  D      R+  +   ++R  ++E ++  +K R    D   +ID +
Sbjct: 297 KNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKER--EKDRSKEIDEK 354

Query: 528 RKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSS 587
           RK+  K R      R  + SR+   + ++ +  +S       +  +   R SS S    S
Sbjct: 355 RKKDKKSR---TPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRS---PS 408

Query: 588 PSSREEKESKKEREEEFKTHHEMKEYS 614
           P SR +K+ K+E+E +  +    +E S
Sbjct: 409 PRSRNKKDKKREKERDHISERRERERS 435



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 34/122 (27%), Positives = 53/122 (43%), Gaps = 5/122 (4%)

Query: 95  PVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSP 154
           P   + + R   R RS +RS  R S  S   R RS+  +RS    RS S +     SKSP
Sbjct: 179 PESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSP 238

Query: 155 VSKRRGSQEKQTKKAEGEPQEE-----SPLKSKSQEEPKDTFEHDPSESIDEFNKSSATS 209
             KR  S+E++  ++    +++       +K K + + KD  +    E   E  K    +
Sbjct: 239 HKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKN 298

Query: 210 GD 211
            D
Sbjct: 299 KD 300



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 83/402 (20%), Positives = 153/402 (38%), Gaps = 46/402 (11%)

Query: 215 GLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGS 274
           G+   D   +  HS + I  PP  +   +   +   +   +   S  S +I+  PE   S
Sbjct: 127 GVMFGDRPLKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIE--PESGKS 184

Query: 275 GSVGNGSSRY---SPSQNSPIHHIPSRRSPAKTIA-----PQNAPRDESRGRSSFYPDGG 326
                G SR    S S++S   H   +RS +K  +      ++  +D  R +S       
Sbjct: 185 NERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSK 244

Query: 327 DQETAKTGKFLKSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDS 386
            +E  K+    +S    K  D REK   +E+  ++ K    +  R + + K       + 
Sbjct: 245 SRERRKSRS--RSHSRDKRKDTREK--IKEKERVKEKDREKEREREKEREK-------EK 293

Query: 387 NRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQ 446
            R  +  +D+          +K++E     +H K     K   +             +++
Sbjct: 294 ERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQD-----------KEKE 342

Query: 447 YFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEEN 506
             K  +  ++E+    +K  ++  T  +S    RR   S S  R+  R     R  +   
Sbjct: 343 REKDRSKEIDEK----RKKDKKSRTPPRSYNASRR-SRSSSRERRRRRSRSSSRSPRTSK 397

Query: 507 QKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDD 566
               K  R  S   R+  D++R E+ ++    +  RE S S ++    +D KE    + +
Sbjct: 398 TIKRKSSRSPSPRSRNKKDKKR-EKERDHISERRERERSTSMRKSSNDRDGKE--KLEKN 454

Query: 567 SKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHH 608
           S   +E++H++       P S  S+E  +    R EE K  H
Sbjct: 455 STSLKEKEHNKE------PDSSVSKEVDDKDAPRTEENKIQH 490



 Score = 37.4 bits (85), Expect = 0.051
 Identities = 50/211 (23%), Positives = 80/211 (37%), Gaps = 37/211 (17%)

Query: 537 DSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKES 596
           +S  S E  G R +  T    K   S K  S+ KR Q   RS S + S S    ++ + S
Sbjct: 180 ESGKSNERKGGRSRSHTRS--KSRSSSKSHSRRKRSQSKHRSRSHNRSRS--RQKDRRRS 235

Query: 597 KKEREEEFKTHHEMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKR 656
           K   ++  K+    K  S      + + T  +I+ + R +                 + R
Sbjct: 236 KSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKE----------------KDR 279

Query: 657 PKEEEWDPEYTPKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTH 716
            KE E + E   K K+   + DRD                +R + R   K+     +   
Sbjct: 280 EKEREREKE-REKEKERGKNKDRDK---------------EREKDREKDKEK-DRERERE 322

Query: 717 DKYQGDGIVEDEEETMENNEEKKDRRKEEKE 747
            +++ D   E E+E  +  E +KDR KE  E
Sbjct: 323 KEHEKDRDKEKEKEQDKEKEREKDRSKEIDE 353



 Score = 35.4 bits (80), Expect = 0.19
 Identities = 35/152 (23%), Positives = 57/152 (37%), Gaps = 20/152 (13%)

Query: 464 KATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHD 523
           K  EE   R +  +      I P + + + R  G  R       +   K           
Sbjct: 157 KELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSH--------- 207

Query: 524 IDRRRKERSKERGDSKG-SRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSS 582
             RR++ +SK R  S   SR     R++ K+P         K     +R +  SRS S  
Sbjct: 208 -SRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHK-------KRSKSRERRKSRSRSHSRD 259

Query: 583 ASPSSPSSREEKE--SKKEREEEFKTHHEMKE 612
               +    +EKE   +K+RE+E +   E ++
Sbjct: 260 KRKDTREKIKEKERVKEKDREKEREREKEREK 291


>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
          Length = 484

 Score = 80.9 bits (198), Expect = 4e-15
 Identities = 71/241 (29%), Positives = 108/241 (44%), Gaps = 26/241 (10%)

Query: 3   RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYR 62
           +   R HS RS+SRS+   R R+ S SR +R  SRSR R++S+SRSR R  S   RR + 
Sbjct: 242 KEEKRRHS-RSRSRSR---RRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHS 297

Query: 63  NNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSS 122
             RG R     + R +               +    ++ S++P +  S +R  + RS S 
Sbjct: 298 RERGRRSRSTSKTRDK--------------KKEDKEKKRSKTPPKSYSTAR--RSRSASR 341

Query: 123 QRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSK 182
           +R R RSR   RS + PRS   +     S+SP S RR  +EK+  K +   ++E    + 
Sbjct: 342 ERRRRRSRSGTRSPKKPRSPKRK----LSRSP-SPRRHKKEKKKDKDKERSRDERERSTS 396

Query: 183 SQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSC 242
            +++ KD  E D     +        + D       YD+         PI T   ++  C
Sbjct: 397 KKKKSKDK-EKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKEC 455

Query: 243 S 243
           S
Sbjct: 456 S 456



 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 66/302 (21%), Positives = 118/302 (39%), Gaps = 21/302 (6%)

Query: 372 PEVKLKMAPVPLDDSN-RPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSE 430
           P +   +A + L  +N    SL  D+LL   L+ +V  + +   +   +  P     TS 
Sbjct: 161 PTLDPALAALGLPGANLNSQSLAADQLLK--LMSTV--DPKLNHVAAGLVSPSLKSDTSS 216

Query: 431 SFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLR 490
             I+  +  V     Q   SAA+  ++      K  +   +R +S    RR   +PS+ R
Sbjct: 217 KEIEEAMKRVREA--QSLISAAIEPDK------KEEKRRHSRSRSRSRRRR---TPSSSR 265

Query: 491 KHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQ 550
            H R     R  +  + K   + R  S   R    R R  RS+    ++  ++    +K+
Sbjct: 266 -HRRSRSRSR--RRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKR 322

Query: 551 EKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEM 610
            KTP   K Y + +      RE+   RS S + SP  P S + K S+       K   + 
Sbjct: 323 SKTPP--KSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKK 380

Query: 611 KEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYTPKS 670
            +    +   R R T  + + + + +     + +  +    T     +E+ +D E   K 
Sbjct: 381 DKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKE 440

Query: 671 KK 672
           +K
Sbjct: 441 EK 442



 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 51/231 (22%), Positives = 88/231 (38%), Gaps = 24/231 (10%)

Query: 517 SADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHS 576
           SA +  D    ++  S+ R  S+  R  S SR +    +  +   S     +  +     
Sbjct: 234 SAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRR 293

Query: 577 RSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFFRIRGRGRAR 636
           RS S      S S+ + ++ KKE +E+ ++    K YS     +R   +  R R R R+R
Sbjct: 294 RSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYS----TARRSRSASRERRRRRSR 349

Query: 637 GVFAGTNTGPNNSNTTFQKRPKEEEWDPEYTPKSKKYFLHDDRDDGVDYWAKRGRGRGTF 696
                       S T   K+P+  +     +P  +++     +D        + + R   
Sbjct: 350 ------------SGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKD--------KDKERSRD 389

Query: 697 QRGRGRFNFKKSGSSPKWTHDKYQGDGIVEDEEETMENNEEKKDRRKEEKE 747
           +R R     KKS    K    K + D  V+      +  E+  D  KE+KE
Sbjct: 390 ERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKE 440



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 35/161 (21%), Positives = 65/161 (40%), Gaps = 11/161 (6%)

Query: 449 KSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQK 508
           KS +     R  S ++      +  +SP+  R      S  RK +R     R  KE+ + 
Sbjct: 328 KSYSTARRSRSASRERRRRRSRSGTRSPKKPR------SPKRKLSRSPSPRRHKKEKKKD 381

Query: 509 GDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSK 568
            DK+   D  +      ++ K++ K+R      R+S   +  ++  +DY E +   D  K
Sbjct: 382 KDKERSRDERERSTSKKKKSKDKEKDR-----ERKSESDKDVKQVTRDYDEEEQGYDSEK 436

Query: 569 HKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHE 609
            K+E+     + S  +      +   +S +E +     HHE
Sbjct: 437 EKKEEKKPIETGSPKTKECSVEKGTGDSLRESKVNGDDHHE 477



 Score = 35.0 bits (79), Expect = 0.25
 Identities = 35/165 (21%), Positives = 65/165 (39%), Gaps = 13/165 (7%)

Query: 442 HVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERV 501
           H +E+  +S + +         K  +   T  KS    RR   +    R+    +G    
Sbjct: 296 HSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSP 355

Query: 502 FKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYK 561
            K  + K  +KL    +  RH   ++ K++ K++  S+  RE S S+K        K+ K
Sbjct: 356 KKPRSPK--RKLSRSPSPRRH---KKEKKKDKDKERSRDERERSTSKK--------KKSK 402

Query: 562 SYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKT 606
             + D + K E D      +          + ++ KKE ++  +T
Sbjct: 403 DKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIET 447


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 80.5 bits (197), Expect = 5e-15
 Identities = 153/655 (23%), Positives = 242/655 (36%), Gaps = 118/655 (18%)

Query: 23  SRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNNRGMRRPYGYRGRGRGYYQ 82
           S+      K R  SRSRS++ SR+RSR   ++R  RR             +R R R Y  
Sbjct: 265 SKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRR-------------HRSRSRSY-- 309

Query: 83  GGGGRYHRGGYRPVWNRRHSRSPRRGRS-RSRSPKRR---SVSSQRSRSRSRRSYRSSRS 138
                          + R   SPRR  S R R+P RR       +RSRS  RR  RSS S
Sbjct: 310 ---------------SPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSAS 354

Query: 139 PRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDT----FEHD 194
              SSS SSS  S+SP  K         +K        SP + + +  P  T      H 
Sbjct: 355 LSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHS 414

Query: 195 PSESIDEFNKSSATSGDIWPGLSA----YDNSPRSPHSPSPIATPPSQSSSCSDAPMLST 250
           P+    + N++  +   + PG ++             SPSP   P     S S+      
Sbjct: 415 PTP--QQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGK 472

Query: 251 VHSAKNTPSQHSHSIQHSPERSGSGS-------------VGNGS----SRYSPSQN-SPI 292
           + +A +   +  +  Q+    S SGS             V NG      R+SPS++ SP 
Sbjct: 473 MAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPS 532

Query: 293 --------------HHIPS------RRSPAKTIAP--QNAPRDESRGRSSFYPDGGDQET 330
                            PS      RRSP+    P  +  P    R R+   P      +
Sbjct: 533 PRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPS 592

Query: 331 AKTGKFLKSPPLHKNLDAREKSTFREES-PLRIKMIASDSHRPEVKLKMAPVPLDDSNRP 389
            +      SPP+ +          R  S P   K  AS S  P+ ++  +P P     R 
Sbjct: 593 PRR----YSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPP---KQRS 645

Query: 390 ASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFK 449
           + +TK R  + +  H  K     RS  +  + PQ +K  S S                 +
Sbjct: 646 SPVTKRRSPSLSSKHR-KGSSPSRSTRE-ARSPQPNKRHSPSPRPRAPQT--SSSPPPVR 701

Query: 450 SAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKG 509
             A +  +R  S   +T       ++PE  ++I  + S   +  R     R      +  
Sbjct: 702 RGASSSPQRRQSPSPSTRPIRRVSRTPE-PKKIKKAASPSPQSVRRVSSSRSVSGSPEPA 760

Query: 510 DKKLRCDSADLRHD-----------IDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYK 558
            KK     + ++             + + +             +E  G +K++K  K +K
Sbjct: 761 AKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHK 820

Query: 559 EYKSYKDDSKHKREQDHSRSSSSSASPSSPS------SREE----KESKKEREEE 603
           + K +K   KHK+E+  + +++++ +P++ +      ++EE     E KKE E E
Sbjct: 821 KDKKHKKHKKHKKEKAVAAAAAAAVTPAAIAAATTTLAQEEPVAAPEPKKETESE 875



 Score = 74.3 bits (181), Expect = 4e-13
 Identities = 149/649 (22%), Positives = 235/649 (36%), Gaps = 105/649 (16%)

Query: 27  SHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNNRGMRRPYGYRGRGRGYYQGGGG 86
           S   K++  +R RSR+ S+SRSR R  S  + R  R +R   R Y  R R          
Sbjct: 265 SKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRP--------- 315

Query: 87  RYHRGGYRPVWNRRHSRSPRRGRS-RSRSPKRRSVSS---QRSRSRSRRSYRSSRSPRSS 142
                            SPRR  S R R+P RR       +RSRS  RR  RSS S   S
Sbjct: 316 -----------------SPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGS 358

Query: 143 SSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDT----FEHDPSES 198
           SS SSS  S+SP  K         +K        SP + + +  P  T      H P+  
Sbjct: 359 SSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQ 418

Query: 199 IDEFNKSSATSGDIWPGLSA----YDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSA 254
             + N++  +   + PG ++             SPSP   P     S S+      + +A
Sbjct: 419 --QSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAA 476

Query: 255 KNTPSQHSHSIQHSPERSGSGS-------------VGNGS----SRYSPSQN-SPI---- 292
            +   +  +  Q+    S SGS             V NG      R+SPS++ SP     
Sbjct: 477 DSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKR 536

Query: 293 ----------HHIPS------RRSPAKTIAPQN--APRDESRGRSSFYPDGGDQETAKTG 334
                        PS      RRSP+    P+    P    R R+   P      + +  
Sbjct: 537 QKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRR- 595

Query: 335 KFLKSPPLHKNLDAREKSTFREESPLRI-KMIASDSHRPEVKLKMAPVPLDDSNRPASLT 393
               SPP+ +          R  SP    K  AS S  P+ ++  +P P     R + +T
Sbjct: 596 ---YSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPP---KQRSSPVT 649

Query: 394 KDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAM 453
           K R  + +  H  K     RS  +  + PQ +K  S S                 +  A 
Sbjct: 650 KRRSPSLSSKHR-KGSSPSRSTRE-ARSPQPNKRHSPSPRPRAPQTSSSPPP--VRRGAS 705

Query: 454 TLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKL 513
           +  +R  S   +T       ++PE  ++I  + S   +  R     R      +   KK 
Sbjct: 706 SSPQRRQSPSPSTRPIRRVSRTPE-PKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKP 764

Query: 514 RCDSADLRHDID----------RRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSY 563
               + ++              ++ K  +      + S +  G +K++K  K  K++K  
Sbjct: 765 PAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKK--KKDKKHKKD 822

Query: 564 KDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKE 612
           K   KHK+ +     ++++A+  +P++     +   +EE        KE
Sbjct: 823 KKHKKHKKHKKEKAVAAAAAAAVTPAAIAAATTTLAQEEPVAAPEPKKE 871



 Score = 67.0 bits (162), Expect = 6e-11
 Identities = 108/433 (24%), Positives = 160/433 (36%), Gaps = 81/433 (18%)

Query: 99  RRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPR-SSSSRSSSP----YSKS 153
           R  SRSPRR +SRS SP+RRS   +R R RS      SRSPR  + SRS SP      K+
Sbjct: 166 RERSRSPRRRKSRSPSPRRRSSPVRRERKRSH-----SRSPRHRTKSRSPSPAPEKKEKT 220

Query: 154 P------VSKRRGSQEKQTKKAE----------GEPQEESPLKSKSQEEPKDTFEHDPSE 197
           P      V  +  S ++ T  ++           EP+E SP K+  +E+ K        E
Sbjct: 221 PELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEK--------E 272

Query: 198 SIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNT 257
                ++S + S       S     PR  H     +  P +  S    P        +  
Sbjct: 273 KTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRM 332

Query: 258 PSQHSHSIQHSP----ERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS--PAKT--IAPQ- 308
           P    H    SP     RS +   G+ SS  S    SP    P R S  P KT  ++P  
Sbjct: 333 PPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSA 392

Query: 309 NAPRDESR--------GRSSFYPDGGDQETAKTGKFLKSPPLHKNLDAREKSTFREESPL 360
           + PR   R         ++   P        +  +   SP        + K T + ESP 
Sbjct: 393 SPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESP- 451

Query: 361 RIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIK 420
                 S + +P  K++++    D   + A+             SV++ +++R       
Sbjct: 452 ------SPAPKPR-KVELSESEEDKGGKMAA-----------ADSVQQRRQYRRQNQQSS 493

Query: 421 LPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQK--SPEI 478
               S S+SE             K  + K+  +    R +  + A+     RQK  SP  
Sbjct: 494 SDSGSSSSSED---------ERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRG 544

Query: 479 HRRIDISPSTLRK 491
            RR   SP   R+
Sbjct: 545 RRRRSPSPPPTRR 557



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 107/495 (21%), Positives = 172/495 (34%), Gaps = 88/495 (17%)

Query: 110 SRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSK-SPVSKRRGSQEKQTKK 168
           S  +  + +    +  +  SR     SRSPR   SRS SP  + SPV + R     ++ +
Sbjct: 143 SMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPR 202

Query: 169 AEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHS 228
              + +  SP   K ++ P+     +PS  + E +   ATS      +   +  P  P  
Sbjct: 203 HRTKSRSPSPAPEKKEKTPE---LPEPSVKVKEPSVQEATSTSDILKVPKPEPIP-EPKE 258

Query: 229 PSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHS-PERSGSGSVGNGSSRYSPS 287
           PSP      +       P   +   +K+     S S  H+ P R       + S R  PS
Sbjct: 259 PSPEKNSKKEKEKEKTRPRSRS--RSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPS 316

Query: 288 ---QNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKSPPLHK 344
              + SP    P RR P      ++      R RSS    G    ++ +    +SPP   
Sbjct: 317 PRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRS--RSPP--- 371

Query: 345 NLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVH 404
                +K   R  SP R     S S  P  + +  P P      P   T+          
Sbjct: 372 -----KKPPKRTSSPPRKTRRLSPSASPP-RRRHRPSP---PATPPPKTR---------- 412

Query: 405 SVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQK 464
                        H   PQ S  T +S +                S +        +  K
Sbjct: 413 -------------HSPTPQQSNRTRKSRV----------------SVSPGRTSGKVTKHK 443

Query: 465 ATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAG-----EERVFKEENQKGDKKLRCDSAD 519
            TE+  +   +P+  R++++S S   K  ++A      + R ++ +NQ+       DS  
Sbjct: 444 GTEKRESPSPAPK-PRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSS----DSGS 498

Query: 520 LRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSS 579
                D R K    + G+    R  S SR    +P+              KR+++ S   
Sbjct: 499 SSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPR--------------KRQKETSPRG 544

Query: 580 SSSASPSSPSSREEK 594
               SPS P +R  +
Sbjct: 545 RRRRSPSPPPTRRRR 559



 Score = 53.1 bits (126), Expect = 9e-07
 Identities = 82/284 (28%), Positives = 112/284 (39%), Gaps = 42/284 (14%)

Query: 3   RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRS-----RDRMYSRDY 57
           RS S S   R K  S    R RS S    +R  S S +    R R+     R R  S   
Sbjct: 527 RSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPP 586

Query: 58  RRDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSP--RRGRSRSRSP 115
           RR   + R    P   R     Y      +       P   RR S SP  +R  S S  P
Sbjct: 587 RRRSPSPRRYSPPIQRR-----YSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPP 641

Query: 116 KRRS--VSSQRSRSRSR---------RSYRSSRSPRSSSSRSSSPY------SKSPVSKR 158
           K+RS  V+ +RS S S          RS R +RSP+ +   S SP       S SP   R
Sbjct: 642 KQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVR 701

Query: 159 RGSQEKQTKKAEGEPQEESPLK--SKSQEEPKDTFEHDPS-ESIDEFNKSSATSGDIWPG 215
           RG+     ++    P    P++  S++ E  K      PS +S+   + S + SG   P 
Sbjct: 702 RGASSSPQRRQSPSPSTR-PIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPA 760

Query: 216 LSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPS 259
                 + + P  PSP+    SQS S + +P +    +   TPS
Sbjct: 761 ------AKKPPAPPSPV---QSQSPSTNWSPAVPVKKAKSPTPS 795



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 83/379 (21%), Positives = 136/379 (35%), Gaps = 43/379 (11%)

Query: 3   RSNSRSHSSRSK-SRSQSSSRSRSRSHSRKKRYSS--RSRSRTYSRS---RSRDRMYSRD 56
           R      SSR K  RS+S  R +SRS S ++R S   R R R++SRS   R++ R  S  
Sbjct: 154 RDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPA 213

Query: 57  YRRDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPK 116
             +  +           +                    P+   +     +  +      K
Sbjct: 214 PEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEK 273

Query: 117 RRSVSSQRSRSRSRRSYRS-----SRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEG 171
            R  S  RS+SRSR   RS      R    S SRS SP  + P  +RR S  ++T     
Sbjct: 274 TRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSP-RRRPSPRRRPSPRRRTPPRRM 332

Query: 172 EP-----QEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSP 226
            P     +  SP++ + +           S S+   + SS++S    P        P+ P
Sbjct: 333 PPPPRHRRSRSPVRRRRRS----------SASLSGSSSSSSSSRSRSP--------PKKP 374

Query: 227 HSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSP 286
             P   ++PP ++   S +          + P+      +HSP    S          SP
Sbjct: 375 --PKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSP 432

Query: 287 SQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQ----ETAKTGKFLKSPPL 342
            + S    +   +   K  +P  AP+      S    D G +    ++ +  +  +    
Sbjct: 433 GRTS--GKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQ 490

Query: 343 HKNLDAREKSTFREESPLR 361
             + D+   S+  +E P R
Sbjct: 491 QSSSDSGSSSSSEDERPKR 509



 Score = 37.4 bits (85), Expect = 0.051
 Identities = 31/121 (25%), Positives = 50/121 (41%), Gaps = 11/121 (9%)

Query: 483 DISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLR------HDIDRRRKERSKERG 536
           ++ P  L     +AG    F E  ++  K+ + +   L        D D+R KE  KE  
Sbjct: 104 ELWPLLLSAQENIAGIPSAFLELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEE-KESS 162

Query: 537 DSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKES 596
             K  R  S  R++ ++P   +         + +R++ HSRS        SPS   EK+ 
Sbjct: 163 REKRERSRSPRRRKSRSPSPRRR----SSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKE 218

Query: 597 K 597
           K
Sbjct: 219 K 219



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 56/238 (23%), Positives = 86/238 (36%), Gaps = 28/238 (11%)

Query: 428 TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS 487
           +++  I  I S    +K++  K   +   E+  S +K  E+   R K  +         S
Sbjct: 111 SAQENIAGIPSAFLELKKEEIKQRQIE-QEKLASMKKQDEDKDKRDKEEK--------ES 161

Query: 488 TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGD---SKGSRES 544
           +  K  R     R          +K R  S   R    RR ++RS  R     +K    S
Sbjct: 162 SREKRERSRSPRR----------RKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPS 211

Query: 545 SGSRKQEKTPKDYKEYKSYKDDSKHK--REQDHSRSSSSSASPSSPSSREEKESKKEREE 602
               K+EKTP+  +     K+ S  +     D  +       P       EK SKKE+E+
Sbjct: 212 PAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEK 271

Query: 603 EFKTHHEMKEYSGFAGVSR---PRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRP 657
           E KT    +  S     +R   P  T  R R R R+R         P    +  ++ P
Sbjct: 272 E-KTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTP 328


>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
          Length = 2426

 Score = 79.7 bits (195), Expect = 9e-15
 Identities = 69/203 (33%), Positives = 97/203 (47%), Gaps = 23/203 (11%)

Query: 3    RSNSRSHSSRSKSRSQSS------SRSRSRSHSRKKRYSSRSRS-----RTYSRSRSRDR 51
            +S  R+  SRS++R +SS      S++RSRS SR++R SSRSRS     R+ S+ + +  
Sbjct: 1835 KSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRS 1894

Query: 52   MYSRDYRRDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSR 111
               R   R+ +  R   R      R R        R H         RR SRS  R RS 
Sbjct: 1895 PKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPS-----RRRRSRSVGRRRSF 1949

Query: 112  SRSPKRRS-VSSQRSRSRSRRSYRSSRSPRSSSSRSSSP--YSKSPVSKRRGSQEKQTKK 168
            S SP RRS   S+RSR+ SRRS   SR  R+ S RS +P   S++P  +RR     + + 
Sbjct: 1950 SISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRS 2009

Query: 169  AEGEP----QEESPLKSKSQEEP 187
                P    +  +PL+ +    P
Sbjct: 2010 FSISPVRLRRSRTPLRRRFSRSP 2032



 Score = 79.0 bits (193), Expect = 2e-14
 Identities = 79/227 (34%), Positives = 107/227 (47%), Gaps = 22/227 (9%)

Query: 3    RSNSRSHSSRSKS-RSQSSSRSRSRSHSRKKRYSSRSRSRTY-----------SRSRSRD 50
            RS +R  SS+SKS RSQ+ SRSRSR   R  R  S+SR R              RS+SR+
Sbjct: 1844 RSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRE 1903

Query: 51   RMYSRDYRRDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWN---RRHSRSP-R 106
            R   R   RD R     R     R R R +      R    G R  ++    R SR+P R
Sbjct: 1904 RKRKRSSSRDNRKTVRARSRTPSR-RSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSR 1962

Query: 107  RGRS---RSRSPKRRS-VSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQ 162
            R R+   RSR+P RRS   S+RSR+ SRRS   SR  RS S      +S SPV  RR   
Sbjct: 1963 RSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRT 2022

Query: 163  EKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATS 209
              + + +    + +    S+    PK   + D ++ + E  K++A +
Sbjct: 2023 PLRRRFSRSPIRRKRSRSSERGRSPKRLTDLDKAQLL-EIAKANAAA 2068



 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 65/199 (32%), Positives = 91/199 (45%), Gaps = 27/199 (13%)

Query: 3    RSNSRSHSSRSKSRSQSSSRSRSR-----SHSRKKRYSSRS---RSRTYSRSRSRDRMYS 54
            +   R  S RS+S+   SS  +SR     S SR ++ SS+S   RS+T SRSRSR R  S
Sbjct: 1814 KEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRS 1873

Query: 55   RDYRRDYRNNRGM---RRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSR 111
               R   R  R +   +R    + R +   +       R   + V  R  SR+P R RSR
Sbjct: 1874 SRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTV--RARSRTPSR-RSR 1930

Query: 112  SRSPKRRSVS-------------SQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKR 158
            S +P RR  S             S+RSR+ SRRS   SR  R+ S RS +P  +S    R
Sbjct: 1931 SHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSR 1990

Query: 159  RGSQEKQTKKAEGEPQEES 177
            R     + +++    +  S
Sbjct: 1991 RSRTPSRRRRSRSVVRRRS 2009



 Score = 63.2 bits (152), Expect = 9e-10
 Identities = 75/256 (29%), Positives = 102/256 (39%), Gaps = 41/256 (16%)

Query: 4    SNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRN 63
            S+ RS S RSKS    S +  S S SR ++ SS+S+S    RS++R R  SR  RR  R+
Sbjct: 1820 SSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSH---RSQTRSRSRSRRRRRSSRS 1876

Query: 64   NRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQ 123
                      + RGR               R V   +  RSP+  RS+SR  KR+  SS+
Sbjct: 1877 RS--------KSRGR---------------RSVSKEKRKRSPKH-RSKSRERKRKRSSSR 1912

Query: 124  ----------RSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRR--GSQEKQTKKAEG 171
                      R+ SR  RS+  SR  RS S      +S SP  + R    + +   +   
Sbjct: 1913 DNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSR 1972

Query: 172  EPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSP-RSPHSPS 230
             P   S   S+    P       PS      +     S  I P       +P R   S S
Sbjct: 1973 TPSRRSRTPSRRSRTPSRR-SRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRS 2031

Query: 231  PIATPPSQSSSCSDAP 246
            PI    S+SS    +P
Sbjct: 2032 PIRRKRSRSSERGRSP 2047



 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 64/235 (27%), Positives = 89/235 (37%), Gaps = 29/235 (12%)

Query: 102  SRSPRRGRSRSRSPKRRSVS----------------SQRSRSRSRRSYRSSRS-PRSSSS 144
            SRS R   S  +S KR S S                  RSRSRSRR  RSSRS  +S   
Sbjct: 1824 SRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGR 1883

Query: 145  RSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNK 204
            RS S   +    K R    ++ +K          ++++S+   + +  H PS      + 
Sbjct: 1884 RSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSV 1943

Query: 205  SSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHS 264
                S  I P   +   S RS  +PS  +  PS+ S         T      TPS+ S +
Sbjct: 1944 GRRRSFSISPSRRSRTPSRRS-RTPSRRSRTPSRRS--------RTPSRRSRTPSRRSRT 1994

Query: 265  IQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRS 319
               S  R     V   S   SP +       P RR  +++   +   R   RGRS
Sbjct: 1995 --PSRRRRSRSVVRRRSFSISPVRLRR-SRTPLRRRFSRSPIRRKRSRSSERGRS 2046



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 89/423 (21%), Positives = 150/423 (35%), Gaps = 48/423 (11%)

Query: 211  DIWPGLSAYDN----SPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQ 266
            D +PG+S  D     S   P +  P AT  S+    + A  LS V+      S  +   +
Sbjct: 1579 DTYPGVSEADAGETLSSTGPFALEPDATGTSKGIEFTTASTLSLVNKYDVDLSLTTQDTE 1638

Query: 267  HSPERSGSGSVGNGSSRYSPSQNSPIH-HIPSRRS----------PAK----TIAPQNAP 311
            H    S S S G+ +    P     IH  +PS  +          P K    T+A   +P
Sbjct: 1639 HDMVISTSPSGGSEADIEGPLPAKDIHLDLPSNNNLVSKDTEEPLPVKESDQTLAALLSP 1698

Query: 312  RDESRGRSSFYPDGGDQETAKTGKF-----------LKSPPLHKNLDAREKSTFREESPL 360
            ++ S G     P    +ET     F           L  P L K+++         E PL
Sbjct: 1699 KESSGGEKEVPPP--PKETLPDSGFSANIEDINEADLVRPLLPKDMERLTSLRAGIEGPL 1756

Query: 361  RIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIK 420
                +  D       +   P    +S+       +  +     H   K+ + R   D  +
Sbjct: 1757 LASDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNR---DKGE 1813

Query: 421  LPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHR 480
              +   S+  S  +   S  H  +++  +S +     R  S +  +    TR +S    R
Sbjct: 1814 KEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRA---RKRSSKSKSHRSQTRSRSRSRRR 1870

Query: 481  RIDISPSTLRKHTRLAGEERVFKEENQKGDK---KLRCDSADLRHDIDRRRKERSKERGD 537
            R      + R  ++  G   V KE+ ++  K   K R          D R+  R++ R  
Sbjct: 1871 R-----RSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTP 1925

Query: 538  SKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESK 597
            S+ SR  + SR++    +     +S+      +      RS + S    +PS R    S+
Sbjct: 1926 SRRSRSHTPSRRRRS--RSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSR 1983

Query: 598  KER 600
            + R
Sbjct: 1984 RSR 1986



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 91/331 (27%), Positives = 130/331 (39%), Gaps = 53/331 (16%)

Query: 1    MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYS-RSRSRDRMYSRDYRR 59
            +GR  S S S   +SR+ S    RSR+ SR+ R  SR RSRT S RSR+  R      RR
Sbjct: 1943 VGRRRSFSISPSRRSRTPS---RRSRTPSRRSRTPSR-RSRTPSRRSRTPSRRSRTPSRR 1998

Query: 60   DYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSP-RRGRSRS----RS 114
              R +R + R        R  +     R  R   R    RR SRSP RR RSRS    RS
Sbjct: 1999 --RRSRSVVR--------RRSFSISPVRLRRS--RTPLRRRFSRSPIRRKRSRSSERGRS 2046

Query: 115  PKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQ 174
            PKR    +   +++     +++ +   + +    P +  P       +EK  KK+ G   
Sbjct: 2047 PKR---LTDLDKAQLLEIAKANAAAMCAKAGVPLPPNLKPAPPPT-IEEKVAKKSGGATI 2102

Query: 175  EESPLKSK---SQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSP 231
            EE   K K     +E  D   + P  S +E  +              + + P     P P
Sbjct: 2103 EELTEKCKQIAQSKEDDDVIVNKPHVSDEEEEE------------PPFYHHPFKLSEPKP 2150

Query: 232  I----------ATPP-SQSSSCSDAPMLS-TVHSAKNTPSQHSHSIQHSPERSGSGSVGN 279
            I           TPP SQ +   + P+ S + H  K   S +   +        +    N
Sbjct: 2151 IFFNLNIAAAKPTPPKSQVTLTKEFPVSSGSQHRKKEADSVYGEWVPVEKNGEENKDDDN 2210

Query: 280  GSSRYSPSQNSPIHHIPSRRSPAKTIAPQNA 310
              S   PS+   I    S R+ A+    +NA
Sbjct: 2211 VFSSNLPSEPVDISTAMSERALAQKRLSENA 2241



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 72/289 (24%), Positives = 110/289 (38%), Gaps = 36/289 (12%)

Query: 111  RSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKS-PVSKRRGSQEKQTKKA 169
            RSRS KR   S  +SR R+  S RS    RSS S+S    ++S   S+RR    +   K+
Sbjct: 1823 RSRS-KRSKSSEHKSRKRTSES-RSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKS 1880

Query: 170  EGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSP 229
             G        + +S +    + E     S    N+ +  +    P   +  ++P      
Sbjct: 1881 RGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRS 1940

Query: 230  SPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQN 289
              +     +S S S +    T      TPS+ S     +P R             +PS+ 
Sbjct: 1941 RSVGR--RRSFSISPSRRSRTPSRRSRTPSRRS----RTPSRRSR----------TPSRR 1984

Query: 290  SPIHHIPSRRSPAKTIAPQNAPRDESRGRS-SFYPDG-GDQETAKTGKFLKSPPLHKNLD 347
            S     PSRRS  +T + +   R   R RS S  P       T    +F +SP   K   
Sbjct: 1985 S---RTPSRRS--RTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRK--- 2036

Query: 348  AREKSTFREESPLRI------KMIASDSHRPEVKLKMAPVPLDDSNRPA 390
             R +S+ R  SP R+      +++             A VPL  + +PA
Sbjct: 2037 -RSRSSERGRSPKRLTDLDKAQLLEIAKANAAAMCAKAGVPLPPNLKPA 2084



 Score = 35.4 bits (80), Expect = 0.19
 Identities = 68/316 (21%), Positives = 122/316 (38%), Gaps = 38/316 (12%)

Query: 127 SRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEE 186
           SR  R       P        S   K   +K++  ++++ KK + +P EES  K+KS ++
Sbjct: 87  SRKSRCVSVQTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYKRQP-EESESKTKSHDD 145

Query: 187 PKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAP 246
                E D     D  ++ SA + ++     A+  S  +  SP+ +  PP  S   S+  
Sbjct: 146 GNIDLESDSFLKFD--SEPSAVALEL--PTRAFGPS-ETNESPAVVLEPPVVSMEVSEPH 200

Query: 247 MLSTVHSAKNT-----------PSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHI 295
           +L T+  A  T             Q   S+   PE S +  + + ++   P+       +
Sbjct: 201 ILETLKPATKTAELSVVSTSVISEQSEQSVAVMPEPSMTKILDSFAAAPVPTTTL----V 256

Query: 296 PSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKSPPLHKNLDAREKSTFR 355
                P  T++ +   +   +   S  P     E +K    L  PP+ K L+  E     
Sbjct: 257 LKSSEPVVTMSVEYQMKSVLKSVESTSP-----EPSKI--MLVEPPVAKVLEPSETLVVS 309

Query: 356 EESPLRIKMIASDSHR---PE------VKLKMAPVPLDDSNRPASLTKDRLLASTLVHSV 406
            E+P  +    S S     PE      ++L   PV +      +S+T+ + L   L  + 
Sbjct: 310 SETPTEVYPEPSTSTTMDFPESSAIEALRLPEQPVDVPSEIADSSMTRPQELPE-LPKTT 368

Query: 407 KKEQEFRSIFDHIKLP 422
             E +  S+   ++LP
Sbjct: 369 ALELQESSVASAMELP 384



 Score = 35.4 bits (80), Expect = 0.19
 Identities = 26/144 (18%), Positives = 57/144 (39%), Gaps = 3/144 (2%)

Query: 463  QKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRH 522
            ++A+E  S  +   EI  ++  +    +K+      E+  K ++    +  R  S++ + 
Sbjct: 1777 ERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHK- 1835

Query: 523  DIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSS 582
               R+R   S+ R   + S+  S   +     +  +  +S +  SK +  +  S+     
Sbjct: 1836 --SRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKR 1893

Query: 583  ASPSSPSSREEKESKKEREEEFKT 606
            +      SRE K  +    +  KT
Sbjct: 1894 SPKHRSKSRERKRKRSSSRDNRKT 1917



 Score = 35.4 bits (80), Expect = 0.19
 Identities = 33/154 (21%), Positives = 58/154 (37%), Gaps = 3/154 (1%)

Query: 503  KEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKS 562
            K+ ++K  K    D  +     D   + RSK    S+       S  + +  K   + KS
Sbjct: 1797 KDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKS 1856

Query: 563  YKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKEYSGFAGVSRP 622
            ++  ++ +      R SS S    S S      SK++R+   K   + +E       SR 
Sbjct: 1857 HRSQTRSRSRSRRRRRSSRS---RSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRD 1913

Query: 623  RGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKR 656
                 R R R  +R   + T +    S +  ++R
Sbjct: 1914 NRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRR 1947



 Score = 31.2 bits (69), Expect = 3.7
 Identities = 16/75 (21%), Positives = 36/75 (48%), Gaps = 2/75 (2%)

Query: 502 FKEENQKGDKKLRCDSA--DLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKE 559
           +K + ++G +K RC S   D   +I  ++ ++ K+  + K  ++    +K ++ P++ + 
Sbjct: 79  YKPDLKEGSRKSRCVSVQTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYKRQPEESES 138

Query: 560 YKSYKDDSKHKREQD 574
                DD     E D
Sbjct: 139 KTKSHDDGNIDLESD 153


>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
          Length = 2303

 Score = 79.7 bits (195), Expect = 9e-15
 Identities = 69/203 (33%), Positives = 97/203 (47%), Gaps = 23/203 (11%)

Query: 3    RSNSRSHSSRSKSRSQSS------SRSRSRSHSRKKRYSSRSRS-----RTYSRSRSRDR 51
            +S  R+  SRS++R +SS      S++RSRS SR++R SSRSRS     R+ S+ + +  
Sbjct: 1835 KSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRS 1894

Query: 52   MYSRDYRRDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSR 111
               R   R+ +  R   R      R R        R H         RR SRS  R RS 
Sbjct: 1895 PKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPS-----RRRRSRSVGRRRSF 1949

Query: 112  SRSPKRRS-VSSQRSRSRSRRSYRSSRSPRSSSSRSSSP--YSKSPVSKRRGSQEKQTKK 168
            S SP RRS   S+RSR+ SRRS   SR  R+ S RS +P   S++P  +RR     + + 
Sbjct: 1950 SISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRS 2009

Query: 169  AEGEP----QEESPLKSKSQEEP 187
                P    +  +PL+ +    P
Sbjct: 2010 FSISPVRLRRSRTPLRRRFSRSP 2032



 Score = 79.0 bits (193), Expect = 2e-14
 Identities = 79/227 (34%), Positives = 107/227 (47%), Gaps = 22/227 (9%)

Query: 3    RSNSRSHSSRSKS-RSQSSSRSRSRSHSRKKRYSSRSRSRTY-----------SRSRSRD 50
            RS +R  SS+SKS RSQ+ SRSRSR   R  R  S+SR R              RS+SR+
Sbjct: 1844 RSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRE 1903

Query: 51   RMYSRDYRRDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWN---RRHSRSP-R 106
            R   R   RD R     R     R R R +      R    G R  ++    R SR+P R
Sbjct: 1904 RKRKRSSSRDNRKTVRARSRTPSR-RSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSR 1962

Query: 107  RGRS---RSRSPKRRS-VSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQ 162
            R R+   RSR+P RRS   S+RSR+ SRRS   SR  RS S      +S SPV  RR   
Sbjct: 1963 RSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRT 2022

Query: 163  EKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATS 209
              + + +    + +    S+    PK   + D ++ + E  K++A +
Sbjct: 2023 PLRRRFSRSPIRRKRSRSSERGRSPKRLTDLDKAQLL-EIAKANAAA 2068



 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 65/199 (32%), Positives = 91/199 (45%), Gaps = 27/199 (13%)

Query: 3    RSNSRSHSSRSKSRSQSSSRSRSR-----SHSRKKRYSSRS---RSRTYSRSRSRDRMYS 54
            +   R  S RS+S+   SS  +SR     S SR ++ SS+S   RS+T SRSRSR R  S
Sbjct: 1814 KEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRS 1873

Query: 55   RDYRRDYRNNRGM---RRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSR 111
               R   R  R +   +R    + R +   +       R   + V  R  SR+P R RSR
Sbjct: 1874 SRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTV--RARSRTPSR-RSR 1930

Query: 112  SRSPKRRSVS-------------SQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKR 158
            S +P RR  S             S+RSR+ SRRS   SR  R+ S RS +P  +S    R
Sbjct: 1931 SHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSR 1990

Query: 159  RGSQEKQTKKAEGEPQEES 177
            R     + +++    +  S
Sbjct: 1991 RSRTPSRRRRSRSVVRRRS 2009



 Score = 63.2 bits (152), Expect = 9e-10
 Identities = 75/256 (29%), Positives = 102/256 (39%), Gaps = 41/256 (16%)

Query: 4    SNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRN 63
            S+ RS S RSKS    S +  S S SR ++ SS+S+S    RS++R R  SR  RR  R+
Sbjct: 1820 SSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSH---RSQTRSRSRSRRRRRSSRS 1876

Query: 64   NRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQ 123
                      + RGR               R V   +  RSP+  RS+SR  KR+  SS+
Sbjct: 1877 RS--------KSRGR---------------RSVSKEKRKRSPKH-RSKSRERKRKRSSSR 1912

Query: 124  ----------RSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRR--GSQEKQTKKAEG 171
                      R+ SR  RS+  SR  RS S      +S SP  + R    + +   +   
Sbjct: 1913 DNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSR 1972

Query: 172  EPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSP-RSPHSPS 230
             P   S   S+    P       PS      +     S  I P       +P R   S S
Sbjct: 1973 TPSRRSRTPSRRSRTPSRR-SRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRS 2031

Query: 231  PIATPPSQSSSCSDAP 246
            PI    S+SS    +P
Sbjct: 2032 PIRRKRSRSSERGRSP 2047



 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 64/235 (27%), Positives = 89/235 (37%), Gaps = 29/235 (12%)

Query: 102  SRSPRRGRSRSRSPKRRSVS----------------SQRSRSRSRRSYRSSRS-PRSSSS 144
            SRS R   S  +S KR S S                  RSRSRSRR  RSSRS  +S   
Sbjct: 1824 SRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGR 1883

Query: 145  RSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNK 204
            RS S   +    K R    ++ +K          ++++S+   + +  H PS      + 
Sbjct: 1884 RSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSV 1943

Query: 205  SSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHS 264
                S  I P   +   S RS  +PS  +  PS+ S         T      TPS+ S +
Sbjct: 1944 GRRRSFSISPSRRSRTPSRRS-RTPSRRSRTPSRRS--------RTPSRRSRTPSRRSRT 1994

Query: 265  IQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRS 319
               S  R     V   S   SP +       P RR  +++   +   R   RGRS
Sbjct: 1995 --PSRRRRSRSVVRRRSFSISPVRLRR-SRTPLRRRFSRSPIRRKRSRSSERGRS 2046



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 89/423 (21%), Positives = 150/423 (35%), Gaps = 48/423 (11%)

Query: 211  DIWPGLSAYDN----SPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQ 266
            D +PG+S  D     S   P +  P AT  S+    + A  LS V+      S  +   +
Sbjct: 1579 DTYPGVSEADAGETLSSTGPFALEPDATGTSKGIEFTTASTLSLVNKYDVDLSLTTQDTE 1638

Query: 267  HSPERSGSGSVGNGSSRYSPSQNSPIH-HIPSRRS----------PAK----TIAPQNAP 311
            H    S S S G+ +    P     IH  +PS  +          P K    T+A   +P
Sbjct: 1639 HDMVISTSPSGGSEADIEGPLPAKDIHLDLPSNNNLVSKDTEEPLPVKESDQTLAALLSP 1698

Query: 312  RDESRGRSSFYPDGGDQETAKTGKF-----------LKSPPLHKNLDAREKSTFREESPL 360
            ++ S G     P    +ET     F           L  P L K+++         E PL
Sbjct: 1699 KESSGGEKEVPPP--PKETLPDSGFSANIEDINEADLVRPLLPKDMERLTSLRAGIEGPL 1756

Query: 361  RIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIK 420
                +  D       +   P    +S+       +  +     H   K+ + R   D  +
Sbjct: 1757 LASDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNR---DKGE 1813

Query: 421  LPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHR 480
              +   S+  S  +   S  H  +++  +S +     R  S +  +    TR +S    R
Sbjct: 1814 KEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRA---RKRSSKSKSHRSQTRSRSRSRRR 1870

Query: 481  RIDISPSTLRKHTRLAGEERVFKEENQKGDK---KLRCDSADLRHDIDRRRKERSKERGD 537
            R      + R  ++  G   V KE+ ++  K   K R          D R+  R++ R  
Sbjct: 1871 R-----RSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTP 1925

Query: 538  SKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESK 597
            S+ SR  + SR++    +     +S+      +      RS + S    +PS R    S+
Sbjct: 1926 SRRSRSHTPSRRRRS--RSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSR 1983

Query: 598  KER 600
            + R
Sbjct: 1984 RSR 1986



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 67/210 (31%), Positives = 92/210 (43%), Gaps = 29/210 (13%)

Query: 1    MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYS-RSRSRDRMYSRDYRR 59
            +GR  S S S   +SR+ S    RSR+ SR+ R  SR RSRT S RSR+  R      RR
Sbjct: 1943 VGRRRSFSISPSRRSRTPS---RRSRTPSRRSRTPSR-RSRTPSRRSRTPSRRSRTPSRR 1998

Query: 60   DYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSP-RRGRSRS----RS 114
              R +R + R        R  +     R  R   R    RR SRSP RR RSRS    RS
Sbjct: 1999 --RRSRSVVR--------RRSFSISPVRLRRS--RTPLRRRFSRSPIRRKRSRSSERGRS 2046

Query: 115  PKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQ 174
            PKR    +   +++     +++ +   + +    P +  P       +EK  KK+ G   
Sbjct: 2047 PKR---LTDLDKAQLLEIAKANAAAMCAKAGVPLPPNLKPAPPPT-IEEKVAKKSGGATI 2102

Query: 175  EESPLKSK---SQEEPKDTFEHDPSESIDE 201
            EE   K K     +E  D   + P  S +E
Sbjct: 2103 EELTEKCKQIAQSKEDDDVIVNKPHVSDEE 2132



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 72/289 (24%), Positives = 110/289 (38%), Gaps = 36/289 (12%)

Query: 111  RSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKS-PVSKRRGSQEKQTKKA 169
            RSRS KR   S  +SR R+  S RS    RSS S+S    ++S   S+RR    +   K+
Sbjct: 1823 RSRS-KRSKSSEHKSRKRTSES-RSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKS 1880

Query: 170  EGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSP 229
             G        + +S +    + E     S    N+ +  +    P   +  ++P      
Sbjct: 1881 RGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRS 1940

Query: 230  SPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQN 289
              +     +S S S +    T      TPS+ S     +P R             +PS+ 
Sbjct: 1941 RSVGR--RRSFSISPSRRSRTPSRRSRTPSRRS----RTPSRRSR----------TPSRR 1984

Query: 290  SPIHHIPSRRSPAKTIAPQNAPRDESRGRS-SFYPDG-GDQETAKTGKFLKSPPLHKNLD 347
            S     PSRRS  +T + +   R   R RS S  P       T    +F +SP   K   
Sbjct: 1985 S---RTPSRRS--RTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRK--- 2036

Query: 348  AREKSTFREESPLRI------KMIASDSHRPEVKLKMAPVPLDDSNRPA 390
             R +S+ R  SP R+      +++             A VPL  + +PA
Sbjct: 2037 -RSRSSERGRSPKRLTDLDKAQLLEIAKANAAAMCAKAGVPLPPNLKPA 2084



 Score = 35.4 bits (80), Expect = 0.19
 Identities = 68/316 (21%), Positives = 122/316 (38%), Gaps = 38/316 (12%)

Query: 127 SRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEE 186
           SR  R       P        S   K   +K++  ++++ KK + +P EES  K+KS ++
Sbjct: 87  SRKSRCVSVQTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYKRQP-EESESKTKSHDD 145

Query: 187 PKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAP 246
                E D     D  ++ SA + ++     A+  S  +  SP+ +  PP  S   S+  
Sbjct: 146 GNIDLESDSFLKFD--SEPSAVALEL--PTRAFGPS-ETNESPAVVLEPPVVSMEVSEPH 200

Query: 247 MLSTVHSAKNT-----------PSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHI 295
           +L T+  A  T             Q   S+   PE S +  + + ++   P+       +
Sbjct: 201 ILETLKPATKTAELSVVSTSVISEQSEQSVAVMPEPSMTKILDSFAAAPVPTTTL----V 256

Query: 296 PSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKSPPLHKNLDAREKSTFR 355
                P  T++ +   +   +   S  P     E +K    L  PP+ K L+  E     
Sbjct: 257 LKSSEPVVTMSVEYQMKSVLKSVESTSP-----EPSKI--MLVEPPVAKVLEPSETLVVS 309

Query: 356 EESPLRIKMIASDSHR---PE------VKLKMAPVPLDDSNRPASLTKDRLLASTLVHSV 406
            E+P  +    S S     PE      ++L   PV +      +S+T+ + L   L  + 
Sbjct: 310 SETPTEVYPEPSTSTTMDFPESSAIEALRLPEQPVDVPSEIADSSMTRPQELPE-LPKTT 368

Query: 407 KKEQEFRSIFDHIKLP 422
             E +  S+   ++LP
Sbjct: 369 ALELQESSVASAMELP 384



 Score = 35.4 bits (80), Expect = 0.19
 Identities = 26/144 (18%), Positives = 57/144 (39%), Gaps = 3/144 (2%)

Query: 463  QKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRH 522
            ++A+E  S  +   EI  ++  +    +K+      E+  K ++    +  R  S++ + 
Sbjct: 1777 ERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHK- 1835

Query: 523  DIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSS 582
               R+R   S+ R   + S+  S   +     +  +  +S +  SK +  +  S+     
Sbjct: 1836 --SRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKR 1893

Query: 583  ASPSSPSSREEKESKKEREEEFKT 606
            +      SRE K  +    +  KT
Sbjct: 1894 SPKHRSKSRERKRKRSSSRDNRKT 1917



 Score = 35.4 bits (80), Expect = 0.19
 Identities = 33/154 (21%), Positives = 58/154 (37%), Gaps = 3/154 (1%)

Query: 503  KEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKS 562
            K+ ++K  K    D  +     D   + RSK    S+       S  + +  K   + KS
Sbjct: 1797 KDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKS 1856

Query: 563  YKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKEYSGFAGVSRP 622
            ++  ++ +      R SS S    S S      SK++R+   K   + +E       SR 
Sbjct: 1857 HRSQTRSRSRSRRRRRSSRS---RSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRD 1913

Query: 623  RGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKR 656
                 R R R  +R   + T +    S +  ++R
Sbjct: 1914 NRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRR 1947



 Score = 31.2 bits (69), Expect = 3.7
 Identities = 16/75 (21%), Positives = 36/75 (48%), Gaps = 2/75 (2%)

Query: 502 FKEENQKGDKKLRCDSA--DLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKE 559
           +K + ++G +K RC S   D   +I  ++ ++ K+  + K  ++    +K ++ P++ + 
Sbjct: 79  YKPDLKEGSRKSRCVSVQTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYKRQPEESES 138

Query: 560 YKSYKDDSKHKREQD 574
                DD     E D
Sbjct: 139 KTKSHDDGNIDLESD 153


>gi|15055543 splicing factor, arginine/serine-rich 2B [Homo sapiens]
          Length = 282

 Score = 79.3 bits (194), Expect = 1e-14
 Identities = 70/183 (38%), Positives = 83/183 (45%), Gaps = 28/183 (15%)

Query: 3   RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRT-YSRSRSRDRMYSRDYRRDY 61
           RS S     RS+SR  S SRSRSRS  R  RYS    SR+ YSRSR     YSR   R+ 
Sbjct: 124 RSRSPRRRHRSRSRGPSCSRSRSRSRYRGSRYSRSPYSRSPYSRSRYSRSPYSRSRYRES 183

Query: 62  RNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSR--SPRRGRSRSRSPKRRS 119
           R                     GG  Y   GY    N R+SR  S R       S   RS
Sbjct: 184 RY--------------------GGSHYSSSGYS---NSRYSRYHSSRSHSKSGSSTSSRS 220

Query: 120 VSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSP-VSKRRGSQEKQTKKAEGEPQEESP 178
            S+ +S S +RRS  SS S   S SRSSS     P VSKR+     ++K+    P+EE  
Sbjct: 221 ASTSKS-SSARRSKSSSVSRSRSRSRSSSMTRSPPRVSKRKSKSRSRSKRPPKSPEEEGQ 279

Query: 179 LKS 181
           + S
Sbjct: 280 MSS 282



 Score = 60.1 bits (144), Expect = 7e-09
 Identities = 70/204 (34%), Positives = 88/204 (43%), Gaps = 29/204 (14%)

Query: 74  RGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRG-RSRSRSPKRRSVSSQRSRSRSRRS 132
           RGR RG   GG GR  R         R SRSPRR  RSRSR P     S  RSRSRSR  
Sbjct: 106 RGRSRG---GGYGRRSRS------YGRRSRSPRRRHRSRSRGP-----SCSRSRSRSR-- 149

Query: 133 YRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFE 192
           YR SR  RS  SRS  PYS+S  S+   S+ +  +   G     S   S S+        
Sbjct: 150 YRGSRYSRSPYSRS--PYSRSRYSRSPYSRSRYRESRYGGSHYSSSGYSNSR-------- 199

Query: 193 HDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVH 252
           +    S    +KS +++       S   ++ RS  S    +   S+SSS + +P    V 
Sbjct: 200 YSRYHSSRSHSKSGSSTSSRSASTSKSSSARRSKSSSVSRSRSRSRSSSMTRSP--PRVS 257

Query: 253 SAKNTPSQHSHSIQHSPERSGSGS 276
             K+     S     SPE  G  S
Sbjct: 258 KRKSKSRSRSKRPPKSPEEEGQMS 281



 Score = 40.0 bits (92), Expect = 0.008
 Identities = 60/222 (27%), Positives = 83/222 (37%), Gaps = 57/222 (25%)

Query: 100 RHSRSPRRGRSRSRSPKRRSVS-SQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKR 158
           R  +   RGRSR     RRS S  +RSRS  RR    SR P  S SRS S Y        
Sbjct: 99  RSRQGEPRGRSRGGGYGRRSRSYGRRSRSPRRRHRSRSRGPSCSRSRSRSRY-------- 150

Query: 159 RGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSA 218
           RGS+  ++      P   SP                                      S 
Sbjct: 151 RGSRYSRS------PYSRSPYSR-----------------------------------SR 169

Query: 219 YDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVG 278
           Y    RSP+S S         S  S +   ++ +S  ++   HS S   +  RS S S  
Sbjct: 170 YS---RSPYSRSRYRESRYGGSHYSSSGYSNSRYSRYHSSRSHSKSGSSTSSRSASTSKS 226

Query: 279 NGSSRYSPSQNSPIHHIPSR-RSPAKTIAPQNAPRDESRGRS 319
           + + R   S++S +    SR RS + T +P    + +S+ RS
Sbjct: 227 SSARR---SKSSSVSRSRSRSRSSSMTRSPPRVSKRKSKSRS 265



 Score = 30.0 bits (66), Expect = 8.2
 Identities = 37/142 (26%), Positives = 49/142 (34%), Gaps = 16/142 (11%)

Query: 462 YQKATEEHSTRQKSPEI-HRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADL 520
           Y + +  +  R +SP   HR     PS  R  +R     R  +       +     S   
Sbjct: 114 YGRRSRSYGRRSRSPRRRHRSRSRGPSCSRSRSR--SRYRGSRYSRSPYSRSPYSRSRYS 171

Query: 521 RHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKH-----KREQDH 575
           R    R R   S+  G    S   S SR        Y  Y S +  SK       R    
Sbjct: 172 RSPYSRSRYRESRYGGSHYSSSGYSNSR--------YSRYHSSRSHSKSGSSTSSRSAST 223

Query: 576 SRSSSSSASPSSPSSREEKESK 597
           S+SSS+  S SS  SR    S+
Sbjct: 224 SKSSSARRSKSSSVSRSRSRSR 245


>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
           sapiens]
          Length = 1031

 Score = 79.0 bits (193), Expect = 2e-14
 Identities = 72/204 (35%), Positives = 89/204 (43%), Gaps = 42/204 (20%)

Query: 1   MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD 60
           MGR  SR +  RS SR +S SRSRSRS S K+  S R   R  SRSR RDR   R   RD
Sbjct: 1   MGRE-SRHYRKRSASRGRSGSRSRSRSPSDKR--SKRGDDRR-SRSRDRDRRRERSRSRD 56

Query: 61  YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 120
            R +R   R    R R R                        R   R R RSRS  RR  
Sbjct: 57  KRRSRSRDRKRLRRSRSR-----------------------ERDRSRERRRSRSRDRR-- 91

Query: 121 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK 180
              RSRSR RR            SRSSSP +KS  ++ R   +++T   E   +++    
Sbjct: 92  -RSRSRSRGRR------------SRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKKDKD 138

Query: 181 SKSQEEPKDTFEHDPSESIDEFNK 204
            K  E+ KD    D ++  +E  K
Sbjct: 139 DKEDEKEKDAGNFDQNKLEEEMRK 162



 Score = 61.2 bits (147), Expect = 3e-09
 Identities = 58/205 (28%), Positives = 81/205 (39%), Gaps = 27/205 (13%)

Query: 3   RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYR 62
           RS SR    R + R +S SR + RS SR ++   RSRSR   RSR R R  SRD RR   
Sbjct: 39  RSRSRD---RDRRRERSRSRDKRRSRSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRS 95

Query: 63  NNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSS 122
            +RG R      G                  +   NR  S+    G   S+  K+     
Sbjct: 96  RSRGRRSRSSSPGNKS---------------KKTENRSRSKEKTDGGESSKEKKKDKDDK 140

Query: 123 QRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQ---EESPL 179
           +  + +   ++  ++       R      K  V K R  Q K+  +  GE +   EE   
Sbjct: 141 EDEKEKDAGNFDQNKLEEEMRKR------KERVEKWREEQRKKAMENIGELKKEIEEMKQ 194

Query: 180 KSKSQEEPKDTFEHDPSESIDEFNK 204
             K   E  D  E DP+E+  E N+
Sbjct: 195 GKKWSLEDDDDDEDDPAEAEKEGNE 219



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 56/208 (26%), Positives = 85/208 (40%), Gaps = 28/208 (13%)

Query: 541 SRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKER 600
           SR  SGSR + ++P D K  K   D     R++D  R  S S       SR+ K  ++ R
Sbjct: 14  SRGRSGSRSRSRSPSD-KRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSR 72

Query: 601 EEEFKTHHEMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEE 660
             E     E +        SR R    R R R R+RG  + +++  N S  T  +   +E
Sbjct: 73  SRERDRSRERRR-------SRSRD---RRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKE 122

Query: 661 EWDPEYTPKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSS-PKWTHDKY 719
           + D   + K KK     D+DD  D   ++ +  G F + +     +K      KW     
Sbjct: 123 KTDGGESSKEKK----KDKDDKED---EKEKDAGNFDQNKLEEEMRKRKERVEKWRE--- 172

Query: 720 QGDGIVEDEEETMENNEEKKDRRKEEKE 747
                 E  ++ MEN  E K   +E K+
Sbjct: 173 ------EQRKKAMENIGELKKEIEEMKQ 194



 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 40/160 (25%), Positives = 72/160 (45%), Gaps = 13/160 (8%)

Query: 458 RFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDK---KLR 514
           R  S +++      R +S +  RR + S S  ++ +R    +R+ +  +++ D+   + R
Sbjct: 25  RSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRERDRSRERRR 84

Query: 515 CDSADLRHDIDRRRKERSKERGDSKGSRESSG-SRKQEKTP--KDYKEYKSYKDDSKHKR 571
             S D R    R R  RS+       S+++   SR +EKT   +  KE K  KDD + ++
Sbjct: 85  SRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKKDKDDKEDEK 144

Query: 572 EQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEMK 611
           E+D      +          EE   +KER E+++     K
Sbjct: 145 EKDAGNFDQNKL-------EEEMRKRKERVEKWREEQRKK 177



 Score = 37.7 bits (86), Expect = 0.039
 Identities = 27/115 (23%), Positives = 45/115 (39%), Gaps = 2/115 (1%)

Query: 490 RKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDR-RRKERSKERGDSKGSRESSGSR 548
           RK +   G            DK+ +          DR RR+ERS+ R D + SR     R
Sbjct: 9   RKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSR-DKRRSRSRDRKR 67

Query: 549 KQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEE 603
            +    ++    +  +      R +  SRS    +  SSP ++ +K   + R +E
Sbjct: 68  LRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKE 122


>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
           containing B [Homo sapiens]
          Length = 546

 Score = 76.3 bits (186), Expect = 1e-13
 Identities = 65/205 (31%), Positives = 94/205 (45%), Gaps = 24/205 (11%)

Query: 12  RSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNNRGMRRPY 71
           RS+SR +  SRSRSR     +R   R R +   R R RDR Y ++   +    R   R  
Sbjct: 329 RSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRER 388

Query: 72  GYRGRGRG------YYQGGGGRYHRGGYRPVWN-RRHSRS-----PRRGRSRSRSPKRRS 119
               R RG      + +    R HR   R     ++HSRS       R RSRSR+  +RS
Sbjct: 389 SKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRS 448

Query: 120 VSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPL 179
               RSRS+ + S   + S   S+ R     S+S    R  S EK  K+     +E+S  
Sbjct: 449 ----RSRSKEKSSKHKNESKEKSNKR-----SRSGSQGRTDSVEKSKKREHSPSKEKSRK 499

Query: 180 KSKSQEEPKDTFEHDPSESIDEFNK 204
           +S+S+E    + + D S+S D+ +K
Sbjct: 500 RSRSKER---SHKRDHSDSKDQSDK 521



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 67/311 (21%), Positives = 131/311 (42%), Gaps = 27/311 (8%)

Query: 442 HVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERV 501
           HV+ +  +S   +L+ R +  +  +  H         HR    S S  R+  R    +R+
Sbjct: 254 HVERRRSRSPRRSLSPRRSPRRSRSRSH---------HREGHGSSSFDRELEREKERQRL 304

Query: 502 FKEENQKGDKKLRCDSADLRHDIDRRR-----KERSKERG-DSKGSRESSGSRKQEKTPK 555
            +E  ++  ++ R  S D    ++RRR     + RS+ R  D KG R      ++++  +
Sbjct: 305 EREAKEREKERRRSRSID--RGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENER 362

Query: 556 DYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKEYSG 615
             +  + Y  +  ++RE++  RS   S    S    EEK+ K+++++  +   + ++   
Sbjct: 363 GRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDR-RHRDDKRDSKK 421

Query: 616 FAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYTPKSKKYFL 675
               SR R    + R R R+R      N G  + + + +K  K +    E + K  +   
Sbjct: 422 EKKHSRSRSRERKHRSRSRSR------NAGKRSRSRSKEKSSKHKNESKEKSNKRSRSG- 474

Query: 676 HDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVEDEEETME-N 734
              R D V+   KR       ++ R R   K+       +  K Q D       +++E  
Sbjct: 475 SQGRTDSVEKSKKREHSPSK-EKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQE 533

Query: 735 NEEKKDRRKEE 745
           ++EK+ + K+E
Sbjct: 534 SQEKQHKNKDE 544



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 53/182 (29%), Positives = 79/182 (43%), Gaps = 14/182 (7%)

Query: 2   GRSNSRSHSS-RSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD 60
           GR   R +   R   R +   RSR RS  ++ R     +     +   R R   RD +++
Sbjct: 363 GRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKE 422

Query: 61  YRNNRGMRRPYGYRGRGRGYYQGGGGRY--------HRGGYRPVWNRRHSRSPRRGRSRS 112
            +++R   R   +R R R    G   R         H+   +   N+R SRS  +GR+ S
Sbjct: 423 KKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKR-SRSGSQGRTDS 481

Query: 113 --RSPKR-RSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYS-KSPVSKRRGSQEKQTKK 168
             +S KR  S S ++SR RSR   RS +   S S   S  +  +   S  + SQEKQ K 
Sbjct: 482 VEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQHKN 541

Query: 169 AE 170
            +
Sbjct: 542 KD 543



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 70/290 (24%), Positives = 99/290 (34%), Gaps = 44/290 (15%)

Query: 99  RRHSRSPRRGRSRSRSPKR-RSVSSQR--------------------------SRSRSRR 131
           RR SRSPRR  S  RSP+R RS S  R                           R + RR
Sbjct: 257 RRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKERR 316

Query: 132 SYRS---------SRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGE----PQEESP 178
             RS         SRS     SRS S   K     R   +EK+ ++         +E   
Sbjct: 317 RSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGN 376

Query: 179 LKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQ 238
            + K +E  ++  +   S    E  K      D        D+     HS S       +
Sbjct: 377 EREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHR 436

Query: 239 SSSCS-DAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPS 297
           S S S +A   S   S + +    + S + S +RS SGS G      S  ++    H PS
Sbjct: 437 SRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTD---SVEKSKKREHSPS 493

Query: 298 RRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKSPPLHKNLD 347
           +    K    +          S    D  D+  +++ +       HKN D
Sbjct: 494 KEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQHKNKD 543



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 32/146 (21%), Positives = 59/146 (40%), Gaps = 6/146 (4%)

Query: 467 EEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGD----KKLRCDSADLRH 522
           E+     K    HR         +KH+R    ER  +  ++  +     + R      +H
Sbjct: 400 EKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKH 459

Query: 523 DIDRRRKERSKERGDSKGSRES-SGSRKQEKTPKDYKEYK-SYKDDSKHKREQDHSRSSS 580
             + + K   + R  S+G  +S   S+K+E +P   K  K S   +  HKR+   S+  S
Sbjct: 460 KNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQS 519

Query: 581 SSASPSSPSSREEKESKKEREEEFKT 606
                    S E++  +K+ + + +T
Sbjct: 520 DKHDRRRSQSIEQESQEKQHKNKDET 545



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 46/229 (20%), Positives = 94/229 (41%), Gaps = 31/229 (13%)

Query: 520 LRHDIDRRRKERSKE-RGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRS 578
           ++ +ID++ K R ++ + D K   E      + +  +  +   S +   +  R + H R 
Sbjct: 225 VQKNIDQQIKTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHRE 284

Query: 579 SSSSASPSSPSSREEKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFFRIRGRGRARGV 638
              S+S      RE++  + ERE + +     +  S   G+ R R    R R R R+R  
Sbjct: 285 GHGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRRS---RSRERHRSRS- 340

Query: 639 FAGTNTGPNNSNTTFQKRPKEEEWDPEYTPKSKKYFLHD-DRDDGVDYWAKRGRGRGTFQ 697
                    + +    +R ++ E + E     ++   +D +R +  +   +R R R   Q
Sbjct: 341 --------RSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQ 392

Query: 698 RGRGRFNFKKSGSSPKWTHDKYQGDGIVEDEEETMENNEEKKDRRKEEK 746
           R RG    KK                  +++++   + ++K+D +KE+K
Sbjct: 393 RSRGEVEEKKH-----------------KEDKDDRRHRDDKRDSKKEKK 424



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 25/68 (36%), Positives = 34/68 (50%), Gaps = 2/68 (2%)

Query: 118 RSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVS-KRRGSQEKQTKKAEGEPQEE 176
           R V  +RSRS  RRS    RSPR S SRS         S  R   +EK+ ++ E E +E 
Sbjct: 253 RHVERRRSRS-PRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKER 311

Query: 177 SPLKSKSQ 184
              + +S+
Sbjct: 312 EKERRRSR 319


>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
          Length = 754

 Score = 76.3 bits (186), Expect = 1e-13
 Identities = 69/214 (32%), Positives = 96/214 (44%), Gaps = 19/214 (8%)

Query: 3   RSNSRSHSSR-SKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDY 61
           R+ SRS     +K +   +SR+R RS SR +  S R RSRT+ R RSR + Y R   ++Y
Sbjct: 541 RAQSRSRECDITKGKHSYNSRTRERSRSRDR--SRRVRSRTHDRDRSRSKEYHRYREQEY 598

Query: 62  RNNRGMRRPYGYR---GRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRR 118
           R  RG  R    R   GR R   +    R  R   R     R+    R   S+S   K  
Sbjct: 599 R-RRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKEN 657

Query: 119 SVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGS------QEKQTKKAEGE 172
           S S +R  S+SR    S+ S    + R  SP+SK   S +         + K+ +K    
Sbjct: 658 SESEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSS 717

Query: 173 PQEESPLKSKSQE-----EPKDTFEHDPSESIDE 201
            ++E+  KSK QE     E    F+H+ S   DE
Sbjct: 718 VEKENQ-KSKGQENDHVHEKNKKFDHESSPGTDE 750



 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 66/214 (30%), Positives = 93/214 (43%), Gaps = 34/214 (15%)

Query: 3   RSNSRSHSSRSKSRSQSSSRS----RSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYR 58
           RS  R H +  +   QS S+     RSRS  + K+  S+S    +S+S+ +DR      R
Sbjct: 488 RSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSR 547

Query: 59  -------------RDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSP 105
                        R    +R   R    R R     +     YHR  YR    RR  RS 
Sbjct: 548 ECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHR--YREQEYRRRGRSR 605

Query: 106 RR------GRSRSRSPKRR---SVSSQR--SRSRSRRSYRSSRSPRSSSSRSSSPYSKSP 154
            R      GRSRS+  +RR   S SS+R  S+SR++  YR+  S +SS  + +S   K  
Sbjct: 606 SRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQES-KSSHRKENSESEKRM 664

Query: 155 VSKRR---GSQEKQTKKAEGEPQEESPLKSKSQE 185
            SK R    S   + KKA+ +    S +K  SQ+
Sbjct: 665 YSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQD 698



 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 65/211 (30%), Positives = 90/211 (42%), Gaps = 40/211 (18%)

Query: 3   RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKR-YSSRSRSRTYSRSRSRDRMYSRDYRRDY 61
           +SN   HS   +   ++ SRSR    ++ K  Y+SR+R R+ SR RSR R+ SR + RD 
Sbjct: 526 KSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSR-RVRSRTHDRD- 583

Query: 62  RNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVS 121
                       R R + Y+     RY    YR           RRGRSRSR    R   
Sbjct: 584 ------------RSRSKEYH-----RYREQEYR-----------RRGRSRSRE---RRTP 612

Query: 122 SQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQT-KKAEGEPQEESPLK 180
             RSRS+ RR  R  R  RSS    S   +K    K R  + K + +K   E ++    K
Sbjct: 613 PGRSRSKDRR--RRRRDSRSSEREESQSRNK---DKYRNQESKSSHRKENSESEKRMYSK 667

Query: 181 SKSQEEPKDTFEHDPSESIDEFNKSSATSGD 211
           S+      ++ E         F+K   +S D
Sbjct: 668 SRDHNSSNNSREKKADRDQSPFSKIKQSSQD 698



 Score = 63.9 bits (154), Expect = 5e-10
 Identities = 107/510 (20%), Positives = 202/510 (39%), Gaps = 58/510 (11%)

Query: 115 PKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQ 174
           PK +    ++ R +S  S  SS S   SSS S S    S  S    + E+++KK + + +
Sbjct: 179 PKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQS---SSDSSDSESATEEKSKKRKKKHR 235

Query: 175 EESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIAT 234
           + S    K +++ K + +   SES  E N  +     + P     +  P  P +   +  
Sbjct: 236 KNSRKHKKEKKKRKKSKKSASSESEAE-NLEAQPQSTVRP-----EEIPPIPENRFLMRK 289

Query: 235 PPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHS--PERSGSGSVGNGSSRYSPSQNSPI 292
            P ++                N P+    S Q      RSG    G G  RY        
Sbjct: 290 SPPKADEKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRY-------- 341

Query: 293 HHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKF-LKSPPLHKNLDAREK 351
                 R+P+++       R   R R S  P    QE  +  +  + S       D  E 
Sbjct: 342 ------RTPSRS-------RSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSEL 388

Query: 352 STFRE--ESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKE 409
           +  +E   SP+R+K      HR    +  +P   ++  +     K       +  + +K+
Sbjct: 389 NEIKENQRSPVRVKERKITDHR---NVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKD 445

Query: 410 QEFRS-IFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTL-NERFTSYQKATE 467
            ++++ +    K    SKS  +S  +   S  +  +E+  +S +    +E     +K ++
Sbjct: 446 DKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSD 505

Query: 468 ---EHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLR-CDSADLRHD 523
              +   R +S E  ++++ S S    H++        KE++++   + R CD    +H 
Sbjct: 506 SKGKDQERSRSKEKSKQLE-SKSNEHDHSK-------SKEKDRRAQSRSRECDITKGKHS 557

Query: 524 IDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRS--SSS 581
            + R +ERS+ R  S+  R  +  R + ++    KEY  Y++    +R +  SR   +  
Sbjct: 558 YNSRTRERSRSRDRSRRVRSRTHDRDRSRS----KEYHRYREQEYRRRGRSRSRERRTPP 613

Query: 582 SASPSSPSSREEKESKKEREEEFKTHHEMK 611
             S S    R  ++S+    EE ++ ++ K
Sbjct: 614 GRSRSKDRRRRRRDSRSSEREESQSRNKDK 643



 Score = 57.8 bits (138), Expect = 4e-08
 Identities = 50/215 (23%), Positives = 89/215 (41%), Gaps = 25/215 (11%)

Query: 5   NSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNN 64
           N     ++SKSRS+S  +S+S+    K   +   R R+ S+ R  + +  ++ + D +  
Sbjct: 450 NKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGK 509

Query: 65  RGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRR-----------------HSRSPRR 107
              R     R + +          H        +RR                 +SR+  R
Sbjct: 510 DQERS----RSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRER 565

Query: 108 GRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTK 167
            RSR RS + RS +  R RSRS+  +R          RS S   ++P  + R    ++ +
Sbjct: 566 SRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRR 625

Query: 168 K-AEGEPQEESPLKSKSQ---EEPKDTFEHDPSES 198
           + +    +EES  ++K +   +E K +   + SES
Sbjct: 626 RDSRSSEREESQSRNKDKYRNQESKSSHRKENSES 660



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 115/619 (18%), Positives = 225/619 (36%), Gaps = 85/619 (13%)

Query: 3   RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYR 62
           R  S S SS S S S SSS S+S S S     ++  +S+   + + + R  SR ++++ +
Sbjct: 190 RHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSK---KRKKKHRKNSRKHKKEKK 246

Query: 63  NNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSS 122
             +  ++                         P+        P       +SP +     
Sbjct: 247 KRKKSKKSASSESEAENLEAQPQSTVRPEEIPPI--------PENRFLMRKSPPKADEKE 298

Query: 123 QRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRG---SQEKQTKKAEGEPQEESPL 179
           +++R R R              R  +P +  P S +R    ++  +  K  G  +  +P 
Sbjct: 299 RKNRERERE-------------RECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPS 345

Query: 180 KSKSQEEPKDTFEHDPS--ESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPS 237
           +S+S++  + + E  P   + +    +   +SG+ W      + +    +  SP+     
Sbjct: 346 RSRSRDRFRRS-ETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRV--- 401

Query: 238 QSSSCSDAPMLSTVHSAKNTPSQ----HSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIH 293
           +    +D   +S   + KN   +    H  + +    R  S       ++      S   
Sbjct: 402 KERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSR 461

Query: 294 HIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKSPPLHKNLDAREKST 353
                +S +K    ++   +E R RS     G D E  K  +        K  D++ K  
Sbjct: 462 SKSKEKSKSKERDSKHNRNEEKRMRSR--SKGRDHENVKEKE--------KQSDSKGKDQ 511

Query: 354 FREESPLRIKMIASDSHRPE-VKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEF 412
            R  S  + K + S S+  +  K K         +R   +TK +   ++      + ++ 
Sbjct: 512 ERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRD- 570

Query: 413 RSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTR 472
           RS     +     +S S+ +        H  +EQ ++        R  S  +       R
Sbjct: 571 RSRRVRSRTHDRDRSRSKEY--------HRYREQEYR-------RRGRSRSRERRTPPGR 615

Query: 473 QKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERS 532
            +S +  RR   S S+ R+ ++   +++   +E++   +K   +S       ++R   +S
Sbjct: 616 SRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSES-------EKRMYSKS 668

Query: 533 KERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSRE 592
           ++   S  SRE       +K  +D   +   K  S     QD+   SS   +      R 
Sbjct: 669 RDHNSSNNSRE-------KKADRDQSPFSKIKQSS-----QDNELKSSMLKNKEDEKIRS 716

Query: 593 --EKESKKEREEEFKTHHE 609
             EKE++K + +E    HE
Sbjct: 717 SVEKENQKSKGQENDHVHE 735



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 118/603 (19%), Positives = 217/603 (35%), Gaps = 116/603 (19%)

Query: 163 EKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNS 222
           E Q   A  +P  E  + S  +  PK   + +  +     + SS++S D           
Sbjct: 155 ENQKTDAASKPFAEVRILSCGELIPKSKVKKEEKKRHKSSSSSSSSSSD----------- 203

Query: 223 PRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSS 282
                  S  ++    SS  SD+   +   S K       +S +H  E+         +S
Sbjct: 204 -------SDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSAS 256

Query: 283 RYSPSQNSPIHHIPSRRSPAKTIAPQNAPR-DESRGRSSFYPDGGDQETAKTGKFLKSPP 341
             S ++N           P  T+ P+  P   E+R      P   D++  K         
Sbjct: 257 SESEAENL-------EAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKN-------- 301

Query: 342 LHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLAST 401
                  RE+   RE +P                          +++PAS  + RLL + 
Sbjct: 302 -------RERERERECNP-------------------------PNSQPASYQR-RLLVTR 328

Query: 402 LVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKE-QYFKSAAMTLNERFT 460
               +K     R      + P  S+S S    +   +  H  +E Q  +   ++  ER+ 
Sbjct: 329 SGRKIKGRGPRR-----YRTP--SRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWI 381

Query: 461 SYQKAT-EEHSTRQKSPEIHRRIDISPSTLRKHTRLA-GEERVFKEENQKGDKKLRCDSA 518
              K+   E    Q+SP     + +    +  H  ++    R  ++E +  D K      
Sbjct: 382 KGDKSELNEIKENQRSP-----VRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKER 436

Query: 519 DLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRS 578
           D+R + ++  K ++K +   K ++  S S+ +EK+       KS + DSKH R ++    
Sbjct: 437 DIRRNSEKDDKYKNKVK---KRAKSKSRSKSKEKS-------KSKERDSKHNRNEEKRMR 486

Query: 579 SSSSASPSSPSSREEKES-----KKEREEEFKTHHEMKEYSGFAGVSRPRGTFFRIRGRG 633
           S S          +EK+S      +ER    +   +++  S     S+ +    R + R 
Sbjct: 487 SRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRS 546

Query: 634 RARGVFAGTNTGPNNSNTTFQKRPKE------EEWDPEYTPKSKKYFLHDDRDDGVDYWA 687
           R   +  G ++   NS T  + R ++               +SK+Y  + +++     + 
Sbjct: 547 RECDITKGKHS--YNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQE-----YR 599

Query: 688 KRGRGRGTFQR---GRGRFNFKKSGSSPKWTHDKYQGDGIVEDEEETMENNEEKKDRRKE 744
           +RGR R   +R   GR R   ++       + ++ +     +D+     N E K   RKE
Sbjct: 600 RRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDK---YRNQESKSSHRKE 656

Query: 745 EKE 747
             E
Sbjct: 657 NSE 659



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 57/270 (21%), Positives = 106/270 (39%), Gaps = 37/270 (13%)

Query: 495 LAGEERVFKEENQKGD---------KKLRCDSADLRHDIDRRRKERSKERGDSKGSRESS 545
           ++G+E V + ENQK D         + L C     +  + +  K+R K    S  S   S
Sbjct: 145 ISGQEVVREIENQKTDAASKPFAEVRILSCGELIPKSKVKKEEKKRHKSSSSSSSSSSDS 204

Query: 546 GSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFK 605
            S    ++  D  + +S  ++   KR++ H +           +SR+ K+ KK+R++  K
Sbjct: 205 DSSSDSQSSSDSSDSESATEEKSKKRKKKHRK-----------NSRKHKKEKKKRKKSKK 253

Query: 606 THHEMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWD-- 663
           +     E       ++P+ T             F    + P       + R +E E +  
Sbjct: 254 SASSESEAENLE--AQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNRERERERECN 311

Query: 664 -PEYTPKSKKYFLHDDRDDGVDYWAKRGRGRG-----TFQRGRGRFNFKKSGSSPKWTHD 717
            P   P S +  L   R        ++ +GRG     T  R R R  F++S + P W  +
Sbjct: 312 PPNSQPASYQRRLLVTRS------GRKIKGRGPRRYRTPSRSRSRDRFRRSETPPHWRQE 365

Query: 718 KYQGDGI-VEDEEETMENNEEKKDRRKEEK 746
             +   + V   E  ++ ++ + +  KE +
Sbjct: 366 MQRAQRMRVSSGERWIKGDKSELNEIKENQ 395



 Score = 33.9 bits (76), Expect = 0.57
 Identities = 22/64 (34%), Positives = 31/64 (48%), Gaps = 2/64 (3%)

Query: 2   GRSNSRSHSSRSK-SRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD 60
           GRS S+    R + SRS     S+SR+  + +   S+S  R    S S  RMYS+    +
Sbjct: 614 GRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRK-ENSESEKRMYSKSRDHN 672

Query: 61  YRNN 64
             NN
Sbjct: 673 SSNN 676


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 75.9 bits (185), Expect = 1e-13
 Identities = 111/492 (22%), Positives = 169/492 (34%), Gaps = 21/492 (4%)

Query: 110  SRSRSPKRRSVSSQRS-RSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKK 168
            S S+S    S SS  S  S S  S  SS S  SS S  SS  S S  S    S +     
Sbjct: 636  SDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSS--SDSSNSSDSSDSS 693

Query: 169  AEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHS 228
                  E S     S  +  D+ +   S S D  + +S+ S D      + D+S  S  S
Sbjct: 694  DSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSS 753

Query: 229  PSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQ 288
             S  ++  S SS  SD+   S    + N+   +  S       S + S  + SS  S S 
Sbjct: 754  DSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSS 813

Query: 289  NSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKSPPLHKNLDA 348
            +S      +    + +    ++        SS   DG D +++       S     + D+
Sbjct: 814  DSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDS 873

Query: 349  REKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKK 408
               S   + S       +SDS              D SN   S + D   +S    S   
Sbjct: 874  SNSSDSSDSSDSNESSNSSDSS-------------DSSNSSDSDSSDSSNSSDSSDSSNS 920

Query: 409  --EQEFRSIFDHIKLPQASKS--TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQK 464
                E  +  D+     +S S  +S+S      S   +  +    S +   N   +S   
Sbjct: 921  SDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSS 980

Query: 465  ATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDI 524
             + + S    S +     D S S+    +  + +     + +   D     DS+D     
Sbjct: 981  NSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSS 1040

Query: 525  DRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSAS 584
            D      S +  DS  S +SS S        D  +     D S+     D S SS SS S
Sbjct: 1041 DSSDSSDSSDSSDSSNSSDSSDS-SDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDS 1099

Query: 585  PSSPSSREEKES 596
              S  S +  +S
Sbjct: 1100 SDSSDSSDSSDS 1111



 Score = 67.4 bits (163), Expect = 5e-11
 Identities = 103/491 (20%), Positives = 165/491 (33%), Gaps = 26/491 (5%)

Query: 112  SRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEG 171
            S S    S SS  S S    S  SS S  S SS SS     S  S    S +    K++ 
Sbjct: 567  SDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDS 626

Query: 172  EPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSP 231
               E     S S+ +  D+   D S++ D  + S++++        + D+S  S  S S 
Sbjct: 627  SKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSS-----DSSDSSDSSDSSSSS 681

Query: 232  IATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSP 291
             ++  S SS  SD+   S    + ++    S     S   + S S  + SS  S S NS 
Sbjct: 682  DSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSS 741

Query: 292  IHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKSPPLHKNLDAREK 351
                 S  S   + +  ++   +S   S         +++ +     S     + D+ + 
Sbjct: 742  ----DSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDS 797

Query: 352  STFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQE 411
            S   + S       +SDS   +           DS+  +S + D   +S        +  
Sbjct: 798  SNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSS-DSSNSSDSSDSSDSSDGSDSDSS 856

Query: 412  FRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHST 471
             RS  D      +S S+  S                  S +   NE   S   +   +S+
Sbjct: 857  NRS--DSSNSSDSSDSSDSS-------------NSSDSSDSSDSNESSNSSDSSDSSNSS 901

Query: 472  RQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKER 531
               S +     D S S+    +  +         +   +     DS+D  +  D      
Sbjct: 902  DSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSD 961

Query: 532  SKERGDSKGSRESSGSRKQEKT-PKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSS 590
            S    DS  S  S  S     +   D  +     D S      D S SS SS S +S  S
Sbjct: 962  SSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDS 1021

Query: 591  REEKESKKERE 601
                +S    +
Sbjct: 1022 SNSSDSSNSSD 1032



 Score = 66.6 bits (161), Expect = 8e-11
 Identities = 125/603 (20%), Positives = 199/603 (33%), Gaps = 15/603 (2%)

Query: 5    NSRSHSSRSKSRSQSSSRSRSRSHSRKKRYS----SRSRSRTYSRSRSRDRMYSRDYRRD 60
            N +S S + KS S  S  S S + S     S    S S S + S S   D   S D    
Sbjct: 537  NDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSS 596

Query: 61   YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 120
              +N                      +          +   S+S     + S S      
Sbjct: 597  DSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDS 656

Query: 121  SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK 180
            S   + S S  S  SS S  SSSS  SS  S S  S    +  + +  ++    + S   
Sbjct: 657  SDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSS 716

Query: 181  SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS 240
              S     D+   + S+S D  N S   S D     ++ D+S  S  S S  ++  S SS
Sbjct: 717  DSSNSNSSDSDSSNSSDSSDSSNSSD--SSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSS 774

Query: 241  SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS 300
              SD+   S  + + N+ S  S S   S   + S S  +  S  S S NS      S  S
Sbjct: 775  DSSDSSNSSDSNDSSNS-SDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSS 833

Query: 301  PAKTIAPQNAPRDESRGRSSFYPDGGDQ----ETAKTGKFLKSPPLHKNLDAREKSTFRE 356
             +   +  +   D S G  S   +  D     +++ +     S     + D+ E S   +
Sbjct: 834  DSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSD 893

Query: 357  ESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIF 416
             S       +  S               DS+  ++ + +   + +   S   +    S  
Sbjct: 894  SSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNS 953

Query: 417  DHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSP 476
                    S ++S+S   +               ++ + +   +S    + + S    S 
Sbjct: 954  SDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1013

Query: 477  EIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSA---DLRHDIDRRRKERSK 533
            +     D S S+   ++  + +     + +   D     DS+   D     D      S 
Sbjct: 1014 DSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 1073

Query: 534  ERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREE 593
            +  DS  S ESS S        D  +     D S      D S SS SS S  S  S + 
Sbjct: 1074 DSSDSSDSSESSDS-SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS 1132

Query: 594  KES 596
             +S
Sbjct: 1133 SDS 1135



 Score = 63.5 bits (153), Expect = 7e-10
 Identities = 137/617 (22%), Positives = 191/617 (30%), Gaps = 63/617 (10%)

Query: 4    SNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRN 63
            S S S SS S S+S SS  + S S        S + S +   S S D   S     D  N
Sbjct: 627  SKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSS-SSDSSN 685

Query: 64   NRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQ 123
            +                                 N   S S     S S      S SS 
Sbjct: 686  SSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSD 745

Query: 124  RS-RSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSK 182
             S  S S  S  SS S  SS S  SS  S S  S         +  ++      S   S 
Sbjct: 746  SSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSN 805

Query: 183  SQE--EPKDTFEHDPSESIDEFNKS----------SATSGDIWPGLSAYDNSPRSPHSPS 230
            S +  +  D+ + D S S D  N S          S+ S D   G S  D+S RS  S S
Sbjct: 806  SSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDG-SDSDSSNRSDSSNS 864

Query: 231  PIATPPSQSSSCSDAPMLSTVHSAKNTP--SQHSHSIQHSPERSGSGSVGNGSSRYSPSQ 288
              ++  S SS+ SD+   S  + + N+   S  S+S       S + S  + SS  S S 
Sbjct: 865  SDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSS 924

Query: 289  NSPIHHIPSRRSPAKTIAPQNAPRDESRGR-------SSFYPDGGDQETAKTGKFLKSPP 341
             S      S  S +   +  +   D S          SS   D  D  ++ +     S  
Sbjct: 925  ESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSD 984

Query: 342  LHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLAST 401
               + D+ + S   + S       +SDS              D SN   S        S+
Sbjct: 985  SSDSSDSSDSSDSSDSSNSSDSSDSSDSS-------------DSSNSSDSSNSSDSSNSS 1031

Query: 402  LVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTS 461
                     +     D      +S S+  S                        +   +S
Sbjct: 1032 DSSDSSDSSDSSDSSDSSDSSDSSNSSDSS------------------------DSSDSS 1067

Query: 462  YQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLR 521
                + + S    S E     D S S+    +  + +     + +   D     +S+D  
Sbjct: 1068 DSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1127

Query: 522  HDIDRRRKERSKERGDSKGSRESSGS--RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSS 579
               D      S    DS  S ESS S          D  +     D S      D S SS
Sbjct: 1128 DSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1187

Query: 580  SSSASPSSPSSREEKES 596
             SS S  S  S +  +S
Sbjct: 1188 DSSDSSDSSDSSDSSDS 1204



 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 124/596 (20%), Positives = 195/596 (32%), Gaps = 19/596 (3%)

Query: 4    SNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRN 63
            SNS   S  S S    SS S   S+S      S + S +   S S D   S D      +
Sbjct: 696  SNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDS 755

Query: 64   NRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQ 123
            +                        +        N   S S     S S +    S SS 
Sbjct: 756  SDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDS-SDSSNSSDSSNSSDSSDSSD 814

Query: 124  RSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKK--AEGEPQEESPLKS 181
             S S S  S  SS S  SS S +SS  S S  S      +   +   +      +S   S
Sbjct: 815  SSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSS 874

Query: 182  KSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSS 241
             S +    +  ++ S S D  + S+++  D     ++ D+S  S  S S  ++  S +S+
Sbjct: 875  NSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSN 934

Query: 242  CSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSP 301
             SD+   S+  S  +  S  S S   S   + S S  + SS  S S NS      S  S 
Sbjct: 935  SSDSSN-SSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSD 993

Query: 302  AKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKSPPLHKNLDAREKSTFREESPLR 361
            +   +  +   D S    S        +++ +     S     + D+ + S   + S   
Sbjct: 994  SSDSSDSSNSSDSSDSSDSS-DSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1052

Query: 362  IKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKL 421
                +SDS         +       +  +S + D   +S    S        S  D    
Sbjct: 1053 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSS-DSSDS 1111

Query: 422  PQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRR 481
              +S S+  S                  +++ + +   +S    + + S    S +    
Sbjct: 1112 SDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDS 1171

Query: 482  IDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGS 541
             D S S+    +  + +     + +   D     DS+D     D      S +  DS  S
Sbjct: 1172 SDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1231

Query: 542  RESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESK 597
             ESS S                 D S      D S SS SS S S  +   + +SK
Sbjct: 1232 NESSDS-------------SDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSK 1274



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 51/179 (28%), Positives = 73/179 (40%), Gaps = 2/179 (1%)

Query: 121  SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK 180
            S+    S S  S  SS S  SS S  SS  S S  S         +  ++     +S   
Sbjct: 1121 SNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNS 1180

Query: 181  SKSQEEPKDTFEHDPSESIDEFNKS-SATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQS 239
            S S +    +   D S+S D  + S S+ S D      + D+S  S  S S  ++  S S
Sbjct: 1181 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDS 1240

Query: 240  SSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGS-VGNGSSRYSPSQNSPIHHIPS 297
            S  SD+   S    + ++    S S   S  +S SG+   NGS   S S+ S  +H  S
Sbjct: 1241 SDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTS 1299



 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 88/468 (18%), Positives = 162/468 (34%), Gaps = 15/468 (3%)

Query: 135 SSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHD 194
           +S S  +SSSR  + Y+ S  SK  G+    +K AE +  + +   + S         +D
Sbjct: 478 NSESDNNSSSRGDASYN-SDESKDNGNGS-DSKGAEDDDSDSTSDTNNSDSNGNGNNGND 535

Query: 195 PSESIDEFN-KSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHS 253
            ++  D    KS ++  D     ++ D+S  S    S   +     SS SD+   S   S
Sbjct: 536 DNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDS 595

Query: 254 AKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRD 313
           + ++ S  S     S + S S    +  S  S S+ S      S+   + + +  ++   
Sbjct: 596 SDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSE-SDSSDSDSKSDSSDSNSSDSSDNS 654

Query: 314 ESRGRSSFYPDGGDQETAKTGKFLKSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPE 373
           +S   S+        +++ +     S     + D+ + S     S       +SDS    
Sbjct: 655 DSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSS- 713

Query: 374 VKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFI 433
                     D S+   S + D   +++   S        S          S  +S+S  
Sbjct: 714 ----------DSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSN 763

Query: 434 QHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHT 493
               S      +    S +   N+   S   +   +S+   +         S  +   ++
Sbjct: 764 SSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNS 823

Query: 494 RLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKT 553
             +       + +   D     DS+D        R + S     S  S  S+ S   + +
Sbjct: 824 SDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSS 883

Query: 554 PKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKERE 601
             +     S   DS +  + D S SS+SS S  S +S +  ES    +
Sbjct: 884 DSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSD 931



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 43/170 (25%), Positives = 67/170 (39%), Gaps = 1/170 (0%)

Query: 121  SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK 180
            S   + S S  S  SS S  SS+S  SS  S+S  S         +  ++     +S   
Sbjct: 1118 SDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDS 1177

Query: 181  SKSQEEPKDTFEHDPSESIDEFNKS-SATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQS 239
            S S +    +   D S+S D  + S S+ S D      + D+S  S  S S  +   S S
Sbjct: 1178 SNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDS 1237

Query: 240  SSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQN 289
            S  SD+   S    + ++      +   + E       GNG++  S S +
Sbjct: 1238 SDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDS 1287



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 54/226 (23%), Positives = 79/226 (34%), Gaps = 2/226 (0%)

Query: 110  SRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKA 169
            S + S    S  S  S   S  S  S  S  S SS SS+    S  S    S +  +  +
Sbjct: 1054 SSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSD-SSDSS 1112

Query: 170  EGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKS-SATSGDIWPGLSAYDNSPRSPHS 228
            +     +S   S S +    +   D S S D  + S S+ S D      + D+S  S  S
Sbjct: 1113 DSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSS 1172

Query: 229  PSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQ 288
             S  ++  S SS  SD+   S    + ++      S       S   S  + SS  S S 
Sbjct: 1173 DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSN 1232

Query: 289  NSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTG 334
             S      S  S +   +  +   D S   S    +   Q  +  G
Sbjct: 1233 ESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNG 1278



 Score = 30.4 bits (67), Expect = 6.3
 Identities = 29/130 (22%), Positives = 43/130 (33%), Gaps = 29/130 (22%)

Query: 502 FKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGD----------------SKGSRE-- 543
           F +++ +GD     D ++   D +      S  RGD                SKG+ +  
Sbjct: 455 FDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDD 514

Query: 544 -----------SSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSRE 592
                      S+G+        D  +    K DS      D S SS SS S  S SS  
Sbjct: 515 SDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDS 574

Query: 593 EKESKKEREE 602
              S  +  +
Sbjct: 575 NSSSDSDSSD 584


>gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo
           sapiens]
          Length = 375

 Score = 73.2 bits (178), Expect = 8e-13
 Identities = 60/186 (32%), Positives = 90/186 (48%), Gaps = 23/186 (12%)

Query: 1   MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD 60
           +  S +     + K R  S  RS SRS SR++R+ SRSR R  SRSRSR+R  SR   R+
Sbjct: 43  LNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRE 102

Query: 61  YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 120
            + +R   R    R R R   +               +R  +RS  R RSRSR  K+R  
Sbjct: 103 RKKSRSRSRERKRRIRSRSRSRSR-------------HRHRTRSRSRTRSRSRDRKKRIE 149

Query: 121 SSQR-SRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPL 179
             +R SRS SR     + SP     R+++  ++  +++R     ++ KK + + ++E   
Sbjct: 150 KPRRFSRSLSR-----TPSPPPFRGRNTAMDAQEALARRL----ERAKKLQEQREKEMVE 200

Query: 180 KSKSQE 185
           K K QE
Sbjct: 201 KQKQQE 206



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 54/176 (30%), Positives = 79/176 (44%), Gaps = 23/176 (13%)

Query: 12  RSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNNRGMRRPY 71
           R +S+ +SS + +S  H+ K+  S + R R  S     DR      R++ +++RG     
Sbjct: 13  RHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDR----HKRKERKSSRGRSHS- 67

Query: 72  GYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRR 131
             R R R        R HR   R     R SRS  R +SRSRS +R+     +SRSRSR 
Sbjct: 68  --RSRSRE-------RRHRSRSRERKKSR-SRSRERKKSRSRSRERK-----KSRSRSRE 112

Query: 132 SYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEP 187
             R  RS   S SR      ++    R  S+ +  KK   +P+  S   S++   P
Sbjct: 113 RKRRIRSRSRSRSRHR---HRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPP 165



 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 45/168 (26%), Positives = 73/168 (43%), Gaps = 13/168 (7%)

Query: 456 NERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRC 515
           N++  S  K  E  ++ +   + H+R +   S  R H+R    ER  +  +++  KK R 
Sbjct: 30  NDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRE-RKKSRS 88

Query: 516 DSADLRHDIDRRR-----KERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHK 570
            S + +    R R     + RS+ER     SR  S SR + +T +     +S   D K +
Sbjct: 89  RSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRT-RSRSRTRSRSRDRKKR 147

Query: 571 REQDHSRSSSSSASPSSPSSR------EEKESKKEREEEFKTHHEMKE 612
            E+    S S S +PS P  R      + +E+   R E  K   E +E
Sbjct: 148 IEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQRE 195



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 56/227 (24%), Positives = 86/227 (37%), Gaps = 37/227 (16%)

Query: 458 RFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDS 517
           R   + K    H ++ KS + H+  + +    ++H+   G ER+   EN +         
Sbjct: 3   RTNFFLKQGRRHESKDKSSKKHKSEEHND---KEHSSDKGRERLNSSENGED-------- 51

Query: 518 ADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSR 577
              RH    +RKER   RG S  SR  S  R+     ++ K+ +S        RE+  SR
Sbjct: 52  ---RH----KRKERKSSRGRSH-SRSRSRERRHRSRSRERKKSRS------RSRERKKSR 97

Query: 578 SSSSSASPSSPSSREEKESKKEREEEFKTH-HEMKEYSGFAGVSRPR-------GTFFRI 629
           S S     S   SRE K   + R      H H  +  S     SR R         F R 
Sbjct: 98  SRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRS 157

Query: 630 RGRGRARGVFAGTNTGPNNSNTTFQK----RPKEEEWDPEYTPKSKK 672
             R  +   F G NT  +      ++    +  +E+ + E   K K+
Sbjct: 158 LSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQ 204



 Score = 34.3 bits (77), Expect = 0.43
 Identities = 28/104 (26%), Positives = 46/104 (44%), Gaps = 14/104 (13%)

Query: 99  RRHS---RSPRRGRSRSRSPKRRSVSSQRSRSRS---------RRSYRSSRSPRSSSSRS 146
           RRH    +S ++ +S   + K  S    R R  S         R+  +SSR    S SRS
Sbjct: 12  RRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRS 71

Query: 147 SS--PYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPK 188
                 S+S   K+  S+ ++ KK+    +E    +S+S+E  +
Sbjct: 72  RERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKR 115



 Score = 30.0 bits (66), Expect = 8.2
 Identities = 44/187 (23%), Positives = 71/187 (37%), Gaps = 14/187 (7%)

Query: 441 HHVKEQYFKSAAMTLN--ERFTSYQKATEEHSTRQKSPEIHR---RIDISPSTLRKHTRL 495
           H+ KE         LN  E      K  E  S+R +S    R   R   S S  RK +R 
Sbjct: 29  HNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRS 88

Query: 496 AGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKE----RGDSKGSRESSGSRKQE 551
              ER       +  KK R  S + +  I  R + RS+     R  S+    S   +K+ 
Sbjct: 89  RSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRI 148

Query: 552 KTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREE-KESKKEREEEFKTHHEM 610
           + P+ +    S        R     R+++  A  +     E  K+ +++RE+E     + 
Sbjct: 149 EKPRRFSRSLSRTPSPPPFR----GRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQ 204

Query: 611 KEYSGFA 617
           +E +  A
Sbjct: 205 QEIAAAA 211


>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
           sapiens]
          Length = 434

 Score = 73.2 bits (178), Expect = 8e-13
 Identities = 60/186 (32%), Positives = 90/186 (48%), Gaps = 23/186 (12%)

Query: 1   MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD 60
           +  S +     + K R  S  RS SRS SR++R+ SRSR R  SRSRSR+R  SR   R+
Sbjct: 102 LNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRE 161

Query: 61  YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 120
            + +R   R    R R R   +               +R  +RS  R RSRSR  K+R  
Sbjct: 162 RKKSRSRSRERKRRIRSRSRSRSR-------------HRHRTRSRSRTRSRSRDRKKRIE 208

Query: 121 SSQR-SRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPL 179
             +R SRS SR     + SP     R+++  ++  +++R     ++ KK + + ++E   
Sbjct: 209 KPRRFSRSLSR-----TPSPPPFRGRNTAMDAQEALARRL----ERAKKLQEQREKEMVE 259

Query: 180 KSKSQE 185
           K K QE
Sbjct: 260 KQKQQE 265



 Score = 67.0 bits (162), Expect = 6e-11
 Identities = 57/186 (30%), Positives = 86/186 (46%), Gaps = 15/186 (8%)

Query: 3   RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYR 62
           +S++     RS+SRS+   R  S+  S KK  S     + +S  + R+R+ S +   D R
Sbjct: 53  KSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGED-R 111

Query: 63  NNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKR-RSVS 121
           + R  R+      RGR         + R   R   +R  SR  ++ RSRSR  K+ RS S
Sbjct: 112 HKRKERK----SSRGRS--------HSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRS 159

Query: 122 SQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKS 181
            +R +SRSR   R  R    S SRS   +     S+ R S+ +  KK   +P+  S   S
Sbjct: 160 RERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTR-SRSRDRKKRIEKPRRFSRSLS 218

Query: 182 KSQEEP 187
           ++   P
Sbjct: 219 RTPSPP 224



 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 59/188 (31%), Positives = 92/188 (48%), Gaps = 17/188 (9%)

Query: 6   SRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNNR 65
           S+ H SRS+SRS+   R   +S +  +++ SRSRS+   R  S+D+  S+ ++ +  N++
Sbjct: 36  SKHHYSRSRSRSRERKR---KSDNEGRKHRSRSRSKEGRRHESKDKS-SKKHKSEEHNDK 91

Query: 66  GMRRPYGYRGRGR-GYYQGGGGRYHRGGYRPVWNRRHSRS---PRRGRSRSRSPKRRSVS 121
                   +GR R    + G  R+ R   +    R HSRS    RR RSRSR  K+    
Sbjct: 92  EHSSD---KGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKK---- 144

Query: 122 SQRSRSRSRRSYRS-SRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK 180
             RSRSR R+  RS SR  + S SRS     +     R  S+ +   ++    +  S  +
Sbjct: 145 -SRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDR 203

Query: 181 SKSQEEPK 188
            K  E+P+
Sbjct: 204 KKRIEKPR 211



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 46/177 (25%), Positives = 73/177 (41%), Gaps = 8/177 (4%)

Query: 465 ATEEHSTRQKSPEIHRRIDISPSTLRKH---TRLAGEERVFKEENQKGDKKLRCDSAD-L 520
           A E+ S  +   +    + +SP   + H   +R    ER  K +N+    + R  S +  
Sbjct: 12  APEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGR 71

Query: 521 RHDI-DRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSS 579
           RH+  D+  K+   E  + K    SS   ++     +  E +  + + K  R + HSRS 
Sbjct: 72  RHESKDKSSKKHKSEEHNDK--EHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSR 129

Query: 580 SSSASPSSPSSREEKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFFRIRGRGRAR 636
           S      S  SRE K+S+    E  K+    +E       SR R    R R R R+R
Sbjct: 130 SRERRHRS-RSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSR 185



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 53/258 (20%), Positives = 97/258 (37%), Gaps = 19/258 (7%)

Query: 495 LAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKER---GDSKGSRESSGSRKQE 551
           LA E+     + +K   ++       +H   R R  RS+ER    D++G +  S SR +E
Sbjct: 11  LAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRS-RSRERKRKSDNEGRKHRSRSRSKE 69

Query: 552 KTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEMK 611
               + K+  S K  S+   +++HS         SS +  +  + K+ +    ++H   +
Sbjct: 70  GRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSR 129

Query: 612 EYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYTPKSK 671
                   SR R    R R R ++R          + S    + R +  E       +S+
Sbjct: 130 --------SRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSR 181

Query: 672 KYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRF--NFKKSGSSPKWTHDKYQGDGIVEDEE 729
               H  R         R R R        RF  +  ++ S P      ++G     D +
Sbjct: 182 SRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPP-----PFRGRNTAMDAQ 236

Query: 730 ETMENNEEKKDRRKEEKE 747
           E +    E+  + +E++E
Sbjct: 237 EALARRLERAKKLQEQRE 254



 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 45/168 (26%), Positives = 73/168 (43%), Gaps = 13/168 (7%)

Query: 456 NERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRC 515
           N++  S  K  E  ++ +   + H+R +   S  R H+R    ER  +  +++  KK R 
Sbjct: 89  NDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRE-RKKSRS 147

Query: 516 DSADLRHDIDRRR-----KERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHK 570
            S + +    R R     + RS+ER     SR  S SR + +T +     +S   D K +
Sbjct: 148 RSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRT-RSRSRTRSRSRDRKKR 206

Query: 571 REQDHSRSSSSSASPSSPSSR------EEKESKKEREEEFKTHHEMKE 612
            E+    S S S +PS P  R      + +E+   R E  K   E +E
Sbjct: 207 IEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQRE 254



 Score = 34.7 bits (78), Expect = 0.33
 Identities = 29/108 (26%), Positives = 45/108 (41%), Gaps = 9/108 (8%)

Query: 104 SPRRGRSRSRS-----PKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKR 158
           SP R + + +S     P+       RSRSRSR   R S     +  R     S+S   +R
Sbjct: 17  SPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKS----DNEGRKHRSRSRSKEGRR 72

Query: 159 RGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSS 206
             S++K +KK + E   +    S    E  ++ E+       +  KSS
Sbjct: 73  HESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSS 120



 Score = 30.0 bits (66), Expect = 8.2
 Identities = 44/187 (23%), Positives = 71/187 (37%), Gaps = 14/187 (7%)

Query: 441 HHVKEQYFKSAAMTLN--ERFTSYQKATEEHSTRQKSPEIHR---RIDISPSTLRKHTRL 495
           H+ KE         LN  E      K  E  S+R +S    R   R   S S  RK +R 
Sbjct: 88  HNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRS 147

Query: 496 AGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKE----RGDSKGSRESSGSRKQE 551
              ER       +  KK R  S + +  I  R + RS+     R  S+    S   +K+ 
Sbjct: 148 RSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRI 207

Query: 552 KTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREE-KESKKEREEEFKTHHEM 610
           + P+ +    S        R     R+++  A  +     E  K+ +++RE+E     + 
Sbjct: 208 EKPRRFSRSLSRTPSPPPFR----GRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQ 263

Query: 611 KEYSGFA 617
           +E +  A
Sbjct: 264 QEIAAAA 270


>gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens]
          Length = 344

 Score = 72.8 bits (177), Expect = 1e-12
 Identities = 61/177 (34%), Positives = 76/177 (42%), Gaps = 18/177 (10%)

Query: 13  SKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNNRGMRRPYG 72
           S  RS S SRSRSRS  R     SRSRSR  SRSRSR    SR   R     R   R  G
Sbjct: 186 SHRRSYSGSRSRSRSRRR-----SRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKG 240

Query: 73  YRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRS 132
            + R +   +    R      R      + +S  R RSRSRSPK       +S+SRSR  
Sbjct: 241 RKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKS--RSRSRSRSPKENGKGDIKSKSRSR-- 296

Query: 133 YRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKD 189
                    S SRS+SP    P   R  S   +   +    +  S  +S+S+   +D
Sbjct: 297 ---------SQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSSSRD 344



 Score = 71.2 bits (173), Expect = 3e-12
 Identities = 63/180 (35%), Positives = 86/180 (47%), Gaps = 17/180 (9%)

Query: 101 HSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRG 160
           + R+ R    + R+  RRS S  RSRSRSRR  RS RS RSS SRS S  SKS    R  
Sbjct: 172 NGRNIRLIEDKPRTSHRRSYSGSRSRSRSRRRSRS-RSRRSSRSRSRS-ISKSRSRSRSR 229

Query: 161 SQEKQTKKAEGEPQEESPLKSKSQEEPKD---TFEHDPSESIDEFNKSSATSGDIWP--- 214
           S+ +   +++G        +SKS+ +PK    +  H  S S DE+ KS + S    P   
Sbjct: 230 SKGRSRSRSKGRKS-----RSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKEN 284

Query: 215 ---GLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPER 271
               + +   S     S SP+  PPS++ S S  P  +T  S   + S+ S S   S  R
Sbjct: 285 GKGDIKSKSRSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSK-SRSRSRSSSR 343



 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 60/153 (39%), Positives = 75/153 (49%), Gaps = 30/153 (19%)

Query: 3   RSNSRSHS-SRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDY 61
           RS SRS S SRS+SRS+S  RSRSRS  RK R  S+S+ ++   S S  R  S+D   +Y
Sbjct: 213 RSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKD---EY 269

Query: 62  RNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSP------ 115
             +R   R    +  G+G  +                   S+S  R +SRS SP      
Sbjct: 270 EKSRSRSRSRSPKENGKGDIK-------------------SKSRSRSQSRSNSPLPVPPS 310

Query: 116 KRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSS 148
           K RSVS    R+ SR   R SRS   S SRSSS
Sbjct: 311 KARSVSPPPKRATSRSRSR-SRSKSRSRSRSSS 342



 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 54/201 (26%), Positives = 75/201 (37%), Gaps = 50/201 (24%)

Query: 1   MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD 60
           M R+  +   +    R+      + R+  R+    SRSRSR+  RSRSR R  SR     
Sbjct: 159 MKRALDKLDGTEINGRNIRLIEDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRS---- 214

Query: 61  YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 120
                                                    SRS  + RSRSRS   RS 
Sbjct: 215 ----------------------------------------RSRSISKSRSRSRS---RSK 231

Query: 121 SSQRSRSRSRRSYRSSRS-PRS--SSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEES 177
              RSRS+ R+S   S+S P+S   S   S   SK    K R     ++ K  G+   +S
Sbjct: 232 GRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKS 291

Query: 178 PLKSKSQEEPKDTFEHDPSES 198
             +S+SQ          PS++
Sbjct: 292 KSRSRSQSRSNSPLPVPPSKA 312



 Score = 38.1 bits (87), Expect = 0.030
 Identities = 37/149 (24%), Positives = 51/149 (34%), Gaps = 17/149 (11%)

Query: 461 SYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVF---KEENQKGDKKLRCDS 517
           S  ++     +R +     R   IS S  R  +R  G  R     ++   K   K + D 
Sbjct: 196 SRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDR 255

Query: 518 ADLRHDIDRRRKERSKERGDSKG--------------SRESSGSRKQEKTPKDYKEYKSY 563
               H   R + E  K R  S+               SR  S SR     P    + +S 
Sbjct: 256 GSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSV 315

Query: 564 KDDSKHKREQDHSRSSSSSASPSSPSSRE 592
               K    +  SRS S S S S  SSR+
Sbjct: 316 SPPPKRATSRSRSRSRSKSRSRSRSSSRD 344



 Score = 37.4 bits (85), Expect = 0.051
 Identities = 33/125 (26%), Positives = 52/125 (41%), Gaps = 5/125 (4%)

Query: 480 RRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRR-KERSKERGDS 538
           R I+  P T   H R     R      ++   + R  S      I + R + RS+ +G S
Sbjct: 177 RLIEDKPRT--SHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRS 234

Query: 539 KGSRESSGSRKQEKT-PKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESK 597
           +   +   SR + K+ PK  +   S+   S+ K E + SRS S S SP      + K   
Sbjct: 235 RSRSKGRKSRSKSKSKPKSDRGSHSHSR-SRSKDEYEKSRSRSRSRSPKENGKGDIKSKS 293

Query: 598 KEREE 602
           + R +
Sbjct: 294 RSRSQ 298



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 36/143 (25%), Positives = 56/143 (39%), Gaps = 13/143 (9%)

Query: 529 KERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSP 588
           K R+  R    GSR  S SR++          +S    S   R +  S+S S S S S  
Sbjct: 182 KPRTSHRRSYSGSRSRSRSRRRS---------RSRSRRSSRSRSRSISKSRSRSRSRSKG 232

Query: 589 SSREEKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNN 648
            SR   + +K R +  K+  +    S     SR +  + + R R R+R   +    G  +
Sbjct: 233 RSRSRSKGRKSRSKS-KSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSR---SPKENGKGD 288

Query: 649 SNTTFQKRPKEEEWDPEYTPKSK 671
             +  + R +     P   P SK
Sbjct: 289 IKSKSRSRSQSRSNSPLPVPPSK 311


>gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]
          Length = 330

 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 58/137 (42%), Positives = 67/137 (48%), Gaps = 21/137 (15%)

Query: 3   RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYR 62
           RS SRS  SRS SRS S S SRSRS SR  R SS S+SR+ S SR R R      R   R
Sbjct: 203 RSKSRSSHSRSSSRSSSPSSSRSRSRSRS-RSSSSSQSRSRSSSRERSRSRGSKSRSSSR 261

Query: 63  NNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSP-------RRGRSRSRSP 115
           ++RG   P     R R Y              P  NR+ SRS        ++ R+RSRSP
Sbjct: 262 SHRGSSSP-----RKRSYSSSSSS--------PERNRKRSRSRSSSSGDRKKRRTRSRSP 308

Query: 116 KRRSVSSQRSRSRSRRS 132
           +RR  SS  S     RS
Sbjct: 309 ERRHRSSSGSSHSGSRS 325



 Score = 70.1 bits (170), Expect = 7e-12
 Identities = 57/155 (36%), Positives = 72/155 (46%), Gaps = 14/155 (9%)

Query: 1   MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRS--RTYSRSRSRDRMYSRDYR 58
           + + N  +      ++ +S+ RSRS+S S   R SSRS S   + SRSRSR R  S    
Sbjct: 180 LSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQS 239

Query: 59  RDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWN--RRHSRSPRRGRSRSRSPK 116
           R   ++R        R R RG       R HRG   P        S SP R R RSRS  
Sbjct: 240 RSRSSSR-------ERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRS 292

Query: 117 RRSVSSQRSRSRSR---RSYRSSRSPRSSSSRSSS 148
             S   ++ R+RSR   R +RSS     S SRSSS
Sbjct: 293 SSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSS 327



 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 59/182 (32%), Positives = 74/182 (40%), Gaps = 48/182 (26%)

Query: 3   RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYR 62
           +SN RS S    S S+SSSRS S S SR +   SRSRSR+ S S+SR R  SR+      
Sbjct: 197 KSNRRSRSKSRSSHSRSSSRSSSPSSSRSR---SRSRSRSSSSSQSRSRSSSRE------ 247

Query: 63  NNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSS 122
                      R R RG                             +SRS S   R  SS
Sbjct: 248 -----------RSRSRG----------------------------SKSRSSSRSHRGSSS 268

Query: 123 QRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSK 182
            R RS S  S    R+ + S SRSSS   +     R  S E++ + + G     S   SK
Sbjct: 269 PRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSSK 328

Query: 183 SQ 184
            +
Sbjct: 329 KK 330



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 36/93 (38%), Positives = 47/93 (50%), Gaps = 9/93 (9%)

Query: 102 SRSPRRGRSRSRSPKRRSVSSQ---------RSRSRSRRSYRSSRSPRSSSSRSSSPYSK 152
           S SP   RSRSRS  R S SSQ         RSRSR  +S  SSRS R SSS     YS 
Sbjct: 217 SSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSS 276

Query: 153 SPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQE 185
           S  S  R  +  +++ +    +++   +S+S E
Sbjct: 277 SSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPE 309



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 43/187 (22%), Positives = 76/187 (40%), Gaps = 2/187 (1%)

Query: 456 NERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDK-KLR 514
           N  +   +++  E+    +  + +R   + P+++ K       E   ++E++   K KL 
Sbjct: 111 NVEYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLD 170

Query: 515 CDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQD 574
            D  +   D+ +   + S+E  DS   + +  SR + ++       +S    S   R + 
Sbjct: 171 EDEDEDDADLSKYNLDASEEE-DSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRS 229

Query: 575 HSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFFRIRGRGR 634
            SRSSSSS S S  SSRE   S+  +       H           S    +  R R R R
Sbjct: 230 RSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSR 289

Query: 635 ARGVFAG 641
           +R   +G
Sbjct: 290 SRSSSSG 296



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 35/87 (40%), Positives = 47/87 (54%), Gaps = 4/87 (4%)

Query: 103 RSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQ 162
           +S RR RS+SRS   RS SS+ S   S RS   SRS  SSSS+S S  S    S+ RGS+
Sbjct: 197 KSNRRSRSKSRSSHSRS-SSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSK 255

Query: 163 EKQTKKA---EGEPQEESPLKSKSQEE 186
            + + ++      P++ S   S S  E
Sbjct: 256 SRSSSRSHRGSSSPRKRSYSSSSSSPE 282



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 41/124 (33%), Positives = 51/124 (41%), Gaps = 1/124 (0%)

Query: 87  RYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRS 146
           R  R   R   +R  SRS     SRSRS + RS SS  S+SRSR S R     R S SRS
Sbjct: 200 RRSRSKSRSSHSRSSSRSSSPSSSRSRS-RSRSRSSSSSQSRSRSSSRERSRSRGSKSRS 258

Query: 147 SSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSS 206
           SS   +   S R+ S    +   E   +      S S +  K        E     +  S
Sbjct: 259 SSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGS 318

Query: 207 ATSG 210
           + SG
Sbjct: 319 SHSG 322



 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 54/193 (27%), Positives = 82/193 (42%), Gaps = 22/193 (11%)

Query: 145 RSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNK 204
           R    Y    V      +E + K++EGE ++E    SK +    D  E +    + ++N 
Sbjct: 129 RKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYK---LDEDEDEDDADLSKYNL 185

Query: 205 SSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHS---AKNTPSQH 261
            ++   D     S    S R   S S   +  S+SSS S +P  S   S   ++++ S  
Sbjct: 186 DASEEED-----SNKKKSNRRSRSKS--RSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQ 238

Query: 262 SHSIQHSPERSGS-GSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSS 320
           S S   S ERS S GS    SSR     +SP      +RS + + +     R  SR RSS
Sbjct: 239 SRSRSSSRERSRSRGSKSRSSSRSHRGSSSP-----RKRSYSSSSSSPERNRKRSRSRSS 293

Query: 321 FYPDGGDQETAKT 333
                GD++  +T
Sbjct: 294 ---SSGDRKKRRT 303



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 40/131 (30%), Positives = 53/131 (40%), Gaps = 8/131 (6%)

Query: 114 SPKRRSVSSQRSRSRSRRSYRSSRS--PRSSSSRSSSPYSKSPVSKRRG-SQEKQTKKAE 170
           S K++S    RS+SRS  S  SSRS  P SS SRS S    S  S+ R  S  ++  ++ 
Sbjct: 193 SNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSR 252

Query: 171 GEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPS 230
           G     S    +    P+       S S +   K S +        S+ D   R   S S
Sbjct: 253 GSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSS-----SSGDRKKRRTRSRS 307

Query: 231 PIATPPSQSSS 241
           P     S S S
Sbjct: 308 PERRHRSSSGS 318



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 39/154 (25%), Positives = 59/154 (38%), Gaps = 13/154 (8%)

Query: 121 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK 180
           +S+   S  ++S R SRS   SS   SS  S SP S R  S+ +    +  + +  S  +
Sbjct: 187 ASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSR 246

Query: 181 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS 240
            +S+           S      + S +  G   P   +Y +S  SP      +   S+SS
Sbjct: 247 ERSR-----------SRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSR--SRSS 293

Query: 241 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGS 274
           S  D     T   +     + S    HS  RS S
Sbjct: 294 SSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSS 327



 Score = 37.0 bits (84), Expect = 0.067
 Identities = 34/142 (23%), Positives = 53/142 (37%), Gaps = 12/142 (8%)

Query: 467 EEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDR 526
           EE S ++KS    R    S      H+R +           +   + R  S+        
Sbjct: 190 EEDSNKKKSNRRSRSKSRS-----SHSRSSSRSSSPSSSRSRSRSRSRSSSSS-----QS 239

Query: 527 RRKERSKERGDSKGSRESSGSRKQEKTPKDYK-EYKSYKDDSKHKREQDHSRSSSSSASP 585
           R +  S+ER  S+GS+  S SR    +    K  Y S     +  R++  SR SSSS   
Sbjct: 240 RSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSR-SSSSGDR 298

Query: 586 SSPSSREEKESKKEREEEFKTH 607
               +R     ++ R     +H
Sbjct: 299 KKRRTRSRSPERRHRSSSGSSH 320


>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
          Length = 1462

 Score = 71.2 bits (173), Expect = 3e-12
 Identities = 184/826 (22%), Positives = 291/826 (35%), Gaps = 166/826 (20%)

Query: 5    NSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNN 64
            NS S  S     S  SS S  RS SR  R  SRS SR+Y+RSRS    +SR         
Sbjct: 670  NSESDQSTYSKYSDRSSESSPRSRSRSSR--SRSYSRSYTRSRSLASSHSRS-------- 719

Query: 65   RGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRR----GRSRSRSPKRRSV 120
                R    R   R  Y           Y  + +    R+ RR    G+  S S K+ S 
Sbjct: 720  ----RSPSSRSHSRNKYSDHSQCSRSSSYTSISSDDGRRAKRRLRSSGKKNSVSHKKHSS 775

Query: 121  SSQ----------RSRSRSRRSYRSSRSP---RSSSSRSSSPYSKSPVSK-RRGSQEKQT 166
            SS+          R RS   R Y  SRS     S S +SS   ++S   K ++G  E+  
Sbjct: 776  SSEKTLHSKYVKGRDRSSCVRKYSESRSSLDYSSDSEQSSVQATQSAQEKEKQGQMERTH 835

Query: 167  KKAEGEPQEESPLKSKSQEE----PKDTFEHDPSESIDEFNKSSATS--GDIWPGLSAYD 220
             K E    EE   KSKS+ E     K T + + S+ +   +K    +  G  W   S  +
Sbjct: 836  NKQEKNRGEE---KSKSERECPHSKKRTLKENLSDHLRNGSKPKRKNYAGSKWDSESNSE 892

Query: 221  -----NSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSG 275
                 NS    H  S      + S S S+   +S +H  K  P+  S +    P+ +G+ 
Sbjct: 893  RDVTKNSKNDSHPSSDKEEGEATSDSESE---VSEIH-IKVKPTTKSSTNTSLPDDNGAW 948

Query: 276  SVGNGSSRYSPSQNSPIHHIPSRRSPA--KTIAPQNAPRDESRGRSSFYPDGGDQETAKT 333
                  +  S S+ S  +   +R  P   K  + +N  R+                T K 
Sbjct: 949  KSSKQRTSTSDSEGSCSNSENNRGKPQKHKHGSKENLKREH---------------TKKV 993

Query: 334  GKFLKSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLT 393
             + LK     K+   + K  F  + PL            E ++    V  +   +  S  
Sbjct: 994  KEKLKGKKDKKHKAPKRKQAFHWQPPLEF------GEEEEEEIDDKQVTQESKEKKVSEN 1047

Query: 394  KDRLLASTLVHSVKKEQEFRSIFDHIK----LPQASKSTSESFI--------QHIVSL-- 439
             + +  + L      E++     D +     L Q +K  S+  I        +++  L  
Sbjct: 1048 NETIKDNILKTEKSSEEDLSGKHDTVTVSSDLDQFTKDDSKLSISPTALNTEENVACLQN 1107

Query: 440  VHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQK----SPEIHRRIDISPSTLRKHTRL 495
            + HV+E         L +   + +  T + S+  K    SP  + R+D     +     +
Sbjct: 1108 IQHVEESVPNGVEDVL-QTDDNMEICTPDRSSPAKVEETSPLGNARLDTPDINIVLKQDM 1166

Query: 496  AGEE---RVFKEENQKGDKKLRCD-------SADLRHDIDRRRKERSKERG-----DSKG 540
            A E     V K+E+   + K+  +       SA L    +   K+   E+      D K 
Sbjct: 1167 ATEHPQAEVVKQESSMSESKVLGEVGKQDSSSASLASAGESTGKKEVAEKSQINLIDKKW 1226

Query: 541  S-----------------------------RESSGSRKQEKTPKDYKEYKSYKDDSKHKR 571
                                           +  G R + K+    +    + +  K  R
Sbjct: 1227 KPLQGVGNLAAPNAATSSAVEVKVLTTVPEMKPQGLRIEIKSKNKVRPGSLFDEVRKTAR 1286

Query: 572  EQDHSRSSSSSASPSSPS----SREEKESKKEREEEFKTHHEMKE--YSGFAGVSRPRGT 625
                 R+  SS+   +PS    S+    S+   + E K+ H  +   YS     SR   +
Sbjct: 1287 LNRRPRNQESSSDEQTPSRDDDSQSRSPSRSRSKSETKSRHRTRSVSYSHSRSRSRSSTS 1346

Query: 626  FFRIRG--RGRARGVFAGTNTGPNNSN--------TTFQKRPKEEEWDPEYTPKSKKYFL 675
             +R R   R R+RG ++   T   +S+        T+ + R +   +DP    +S  Y  
Sbjct: 1347 SYRSRSYSRSRSRGWYSRGRTRSRSSSYRSYKSHRTSSRSRSRSSSYDPHSRSRSYTY-- 1404

Query: 676  HDDRDDGVDYWAKRGRGRGTFQRG----RGRFNFKKSGSSPKWTHD 717
                    D +  R R R   QR     RGR   ++S S   +  D
Sbjct: 1405 --------DSYYSRSRSRSRSQRSDSYHRGRSYNRRSRSCRSYGSD 1442



 Score = 70.5 bits (171), Expect = 5e-12
 Identities = 65/178 (36%), Positives = 84/178 (47%), Gaps = 20/178 (11%)

Query: 4    SNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRN 63
            S+ ++ S    S+S+S SRSRS+S ++ +    R+RS +YS SRSR R  +  YR     
Sbjct: 1298 SDEQTPSRDDDSQSRSPSRSRSKSETKSRH---RTRSVSYSHSRSRSRSSTSSYRS---- 1350

Query: 64   NRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVS-- 121
                 R Y  R R RG+Y  G  R     YR   + R S S  R RS S  P  RS S  
Sbjct: 1351 -----RSYS-RSRSRGWYSRGRTRSRSSSYRSYKSHRTS-SRSRSRSSSYDPHSRSRSYT 1403

Query: 122  --SQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEES 177
              S  SRSRSR   RS RS      RS +  S+S  S    S+  ++      P E S
Sbjct: 1404 YDSYYSRSRSRS--RSQRSDSYHRGRSYNRRSRSCRSYGSDSESDRSYSHHRSPSESS 1459



 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 119/536 (22%), Positives = 202/536 (37%), Gaps = 80/536 (14%)

Query: 93  YRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSP-RSSSSRSSSPYS 151
           YRP    + S+  +     S     RS+S QRSRS S   Y S  S  R S         
Sbjct: 375 YRPPSGEKWSKGDKLSDPCSSRWDERSLS-QRSRSWSYNGYYSDLSTARHSGHHKKRRKE 433

Query: 152 KSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGD 211
           K    K++G ++K  ++ +   +    + S  +     T     S   +  ++SS+    
Sbjct: 434 KKVKHKKKGKKQKHCRRHKQTKKRRILIPSDIESSKSSTRRMKSSCDRERSSRSSS---- 489

Query: 212 IWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPER 271
               LS++ +S R              S S  D    S  HS++++    SHS  +S   
Sbjct: 490 ----LSSHHSSKRD------------WSKSDKDVQS-SLTHSSRDSYRSKSHSQSYS--- 529

Query: 272 SGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETA 331
                   GSSR   +  S  H                  R  S+ RSS     G ++ A
Sbjct: 530 -------RGSSRSRTASKSSSHS-----------------RSRSKSRSS--SKSGHRKRA 563

Query: 332 KTGKFLKSPPLHKNLDAREKSTFREESPLRIKMIASDSH--RPEVKLKMAPVPLDDSNRP 389
                  +  L +N   + +       PLR  M  +++   +P V   +  +PL DS  P
Sbjct: 564 SKSPRKTASQLSENKPVKTE-------PLRATMAQNENVVVQPVVAENIPVIPLSDSPPP 616

Query: 390 ASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFK 449
           +     +        S ++ QE ++   H+ LP  S  +  +  +   S  +H +E+  +
Sbjct: 617 SRWKPGQ---KPWKPSYERIQEMKAKTTHL-LPIQSTYSLANIKETGSSSSYHKREKNSE 672

Query: 450 SAAMTLNERFTSYQKATEEHSTRQKSPEIHRR-----IDISPSTLRKHTRLAGEERVFKE 504
           S   T    ++ Y   + E S R +S     R        S S    H+R          
Sbjct: 673 SDQST----YSKYSDRSSESSPRSRSRSSRSRSYSRSYTRSRSLASSHSRSRSPSSRSHS 728

Query: 505 ENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKD--YKEYKS 562
            N+  D   +C  +     I      R+K R  S G + S   +K   + +   + +Y  
Sbjct: 729 RNKYSDHS-QCSRSSSYTSISSDDGRRAKRRLRSSGKKNSVSHKKHSSSSEKTLHSKYVK 787

Query: 563 YKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEE---FKTHHEMKEYSG 615
            +D S   R+   SRSS   +S S  SS +  +S +E+E++    +TH++ ++  G
Sbjct: 788 GRDRSSCVRKYSESRSSLDYSSDSEQSSVQATQSAQEKEKQGQMERTHNKQEKNRG 843



 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 142/631 (22%), Positives = 234/631 (37%), Gaps = 101/631 (16%)

Query: 1    MGRSNSRSHSSRSKSRSQSSSRSR-----------SRSHSRKKRYSSRSRSRTYSRSRSR 49
            M  S  R  SSRS S S   S  R           S +HS +  Y S+S S++YSR  SR
Sbjct: 475  MKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQSYSRGSSR 534

Query: 50   DRMYSRDYRRDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGR 109
             R  S+                    R R   +      HR        +R S+SPR  +
Sbjct: 535  SRTASKS---------------SSHSRSRSKSRSSSKSGHR--------KRASKSPR--K 569

Query: 110  SRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKA 169
            + S+  + + V ++  R+   ++      P  + +    P S SP   R    +K  K +
Sbjct: 570  TASQLSENKPVKTEPLRATMAQNENVVVQPVVAENIPVIPLSDSPPPSRWKPGQKPWKPS 629

Query: 170  EGEPQEESP-----LKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPR 224
                QE        L  +S     +  E   S S  +  K+S +    +   S   +S  
Sbjct: 630  YERIQEMKAKTTHLLPIQSTYSLANIKETGSSSSYHKREKNSESDQSTYSKYSD-RSSES 688

Query: 225  SPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRY 284
            SP S S  +   S S S + +  L++ HS   +PS  SHS                 ++Y
Sbjct: 689  SPRSRSRSSRSRSYSRSYTRSRSLASSHSRSRSPSSRSHS----------------RNKY 732

Query: 285  SPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKS--PPL 342
            S       H   SR S   +I+  +  R + R RSS     G + +    K   S    L
Sbjct: 733  SD------HSQCSRSSSYTSISSDDGRRAKRRLRSS-----GKKNSVSHKKHSSSSEKTL 781

Query: 343  H-KNLDAREKST-FREESPLRIKM-IASDSHRPEV--------KLKMAPVPLDDSNRPAS 391
            H K +  R++S+  R+ S  R  +  +SDS +  V        K K   +    + +  +
Sbjct: 782  HSKYVKGRDRSSCVRKYSESRSSLDYSSDSEQSSVQATQSAQEKEKQGQMERTHNKQEKN 841

Query: 392  LTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSA 451
              +++  +       KK     ++ DH++    SK   +++         + +    K++
Sbjct: 842  RGEEKSKSERECPHSKKRTLKENLSDHLR--NGSKPKRKNYAGSKWDSESNSERDVTKNS 899

Query: 452  AMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRK-HTRLAGEERVFKEENQKGD 510
                N+   S  K   E ++  +S      I + P+T    +T L  +   +K   Q   
Sbjct: 900  K---NDSHPSSDKEEGEATSDSESEVSEIHIKVKPTTKSSTNTSLPDDNGAWKSSKQ--- 953

Query: 511  KKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHK 570
               R  ++D           R K +    GS+E   + K+E T K  KE    K D KHK
Sbjct: 954  ---RTSTSDSEGSCSNSENNRGKPQKHKHGSKE---NLKREHT-KKVKEKLKGKKDKKHK 1006

Query: 571  REQDHSRSSSSSASPSSPSSREEKESKKERE 601
              +   R  +    P      EE+E   +++
Sbjct: 1007 APK---RKQAFHWQPPLEFGEEEEEEIDDKQ 1034



 Score = 63.5 bits (153), Expect = 7e-10
 Identities = 147/688 (21%), Positives = 235/688 (34%), Gaps = 108/688 (15%)

Query: 2   GRSNSRSHS---SRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYR 58
           GR   R H+   SRS S S     S +  H +++      R R Y R  S ++    D  
Sbjct: 335 GRGTIRYHTPPRSRSCSESDDDDSSETPPHWKEEM----QRLRAY-RPPSGEKWSKGDKL 389

Query: 59  RDYRNNRGMRRPYGYRGRG---RGYYQGGGGRYHRG----------------GYRPVWNR 99
            D  ++R   R    R R     GYY       H G                G +    R
Sbjct: 390 SDPCSSRWDERSLSQRSRSWSYNGYYSDLSTARHSGHHKKRRKEKKVKHKKKGKKQKHCR 449

Query: 100 RHSR-----------------SPRRGRS---RSRSPKRRSVSSQRSRSR----------- 128
           RH +                 S RR +S   R RS +  S+SS  S  R           
Sbjct: 450 RHKQTKKRRILIPSDIESSKSSTRRMKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQS 509

Query: 129 -----SRRSYRS---SRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK 180
                SR SYRS   S+S    SSRS +    S  S+ R      +K    +   +SP K
Sbjct: 510 SLTHSSRDSYRSKSHSQSYSRGSSRSRTASKSSSHSRSRSKSRSSSKSGHRKRASKSPRK 569

Query: 181 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS 240
           + SQ       + +P  +    N++      +       +N P  P S SP   PPS+  
Sbjct: 570 TASQLSENKPVKTEPLRATMAQNENVVVQPVV------AENIPVIPLSDSP---PPSRWK 620

Query: 241 SCSD--APMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSR 298
                  P    +   K   + H   IQ +   +     G+ SS +   +NS      S 
Sbjct: 621 PGQKPWKPSYERIQEMK-AKTTHLLPIQSTYSLANIKETGSSSSYHKREKNSESDQ--ST 677

Query: 299 RSPAKTIAPQNAPRDESR-GRSSFYPDGGDQETAKTGKFLKSPPLHKNLDAREKSTFREE 357
            S     + +++PR  SR  RS  Y     +  +      +S        +R K +   +
Sbjct: 678 YSKYSDRSSESSPRSRSRSSRSRSYSRSYTRSRSLASSHSRSRSPSSRSHSRNKYSDHSQ 737

Query: 358 ---SPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHS------VKK 408
              S     + + D  R + +L+ +      S++  S + ++ L S  V        V+K
Sbjct: 738 CSRSSSYTSISSDDGRRAKRRLRSSGKKNSVSHKKHSSSSEKTLHSKYVKGRDRSSCVRK 797

Query: 409 EQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEE 468
             E RS  D+      S  + +S +Q   S      ++  K   M          +  E+
Sbjct: 798 YSESRSSLDY------SSDSEQSSVQATQS-----AQEKEKQGQMERTHNKQEKNRGEEK 846

Query: 469 HSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRR 528
             + ++ P  H +       L  H R   + +       K D +   +    ++  +   
Sbjct: 847 SKSERECP--HSKKRTLKENLSDHLRNGSKPKRKNYAGSKWDSESNSERDVTKNSKNDSH 904

Query: 529 KERSKERGDSKGSRESSGSR---KQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASP 585
               KE G++    ES  S    K + T K         D+   K  +  + +S S  S 
Sbjct: 905 PSSDKEEGEATSDSESEVSEIHIKVKPTTKSSTNTSLPDDNGAWKSSKQRTSTSDSEGSC 964

Query: 586 SSPSSREEKESKKER--EEEFKTHHEMK 611
           S+  +   K  K +   +E  K  H  K
Sbjct: 965 SNSENNRGKPQKHKHGSKENLKREHTKK 992



 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 57/144 (39%), Positives = 66/144 (45%), Gaps = 11/144 (7%)

Query: 3    RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYR 62
            RS S SHS RS+SRS +SS  RSRS+SR +     SR RT SRS S      R Y+    
Sbjct: 1330 RSVSYSHS-RSRSRSSTSSY-RSRSYSRSRSRGWYSRGRTRSRSSS-----YRSYKSHRT 1382

Query: 63   NNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSS 122
            ++R   R   Y    R         Y R   R     R  RS    R RS + + RS  S
Sbjct: 1383 SSRSRSRSSSYDPHSRSRSYTYDSYYSRSRSR----SRSQRSDSYHRGRSYNRRSRSCRS 1438

Query: 123  QRSRSRSRRSYRSSRSPRSSSSRS 146
              S S S RSY   RSP  SS  S
Sbjct: 1439 YGSDSESDRSYSHHRSPSESSRYS 1462



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 119/572 (20%), Positives = 201/572 (35%), Gaps = 79/572 (13%)

Query: 111 RSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAE 170
           + R     S  S  S + S  S  SS S           + + P  KR   + K+   +E
Sbjct: 187 KKRKKPTHSEGSDSSSNSSSSSESSSESELEHERSRRRKHKRRPKVKRSKKRRKEASSSE 246

Query: 171 GEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPS 230
            EP+ +  +  K   E  DT E    +S  +  K      +I P       +        
Sbjct: 247 -EPRNKHAMNPKGHSERSDTNEKRSVDSSAKREKPVVRPEEIPP----VPENRFLLRRDM 301

Query: 231 PIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQ-------HSPERSGSGSVG--NGS 281
           P+ T   +      AP++S     K + S+    I+       H+P RS S S    + S
Sbjct: 302 PVVTAEPEPKIPDVAPIVS---DQKPSVSKSGRKIKGRGTIRYHTPPRSRSCSESDDDDS 358

Query: 282 SRYSPSQNSPIHHIPSRRSPA--------KTIAPQNAPRDE----SRGRS----SFYPD- 324
           S   P     +  + + R P+        K   P ++  DE     R RS     +Y D 
Sbjct: 359 SETPPHWKEEMQRLRAYRPPSGEKWSKGDKLSDPCSSRWDERSLSQRSRSWSYNGYYSDL 418

Query: 325 -----GGDQETAKTGKFLKSPPLHKNLDAREKSTFR-EESPLRIKMIASD--SHRPEVKL 376
                 G  +  +  K +K    HK    ++K   R +++  R  +I SD  S +   + 
Sbjct: 419 STARHSGHHKKRRKEKKVK----HKKKGKKQKHCRRHKQTKKRRILIPSDIESSKSSTRR 474

Query: 377 KMAPVPLDDSNRPASLT-----------KDRLLASTLVHSVK-------KEQEFRSIFDH 418
             +    + S+R +SL+            D+ + S+L HS +         Q +      
Sbjct: 475 MKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQSYSRGSSR 534

Query: 419 IKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATE-------EHST 471
            +    S S S S  +   S     +++  KS   T ++   +    TE       ++  
Sbjct: 535 SRTASKSSSHSRSRSKSRSSSKSGHRKRASKSPRKTASQLSENKPVKTEPLRATMAQNEN 594

Query: 472 RQKSPEIHRRIDISP-STLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKE 530
               P +   I + P S     +R    ++ +K   ++  ++++  +  L          
Sbjct: 595 VVVQPVVAENIPVIPLSDSPPPSRWKPGQKPWKPSYER-IQEMKAKTTHLLPIQSTYSLA 653

Query: 531 RSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSS-SSSASPSSPS 589
             KE G S     SS  ++++ +  D   Y  Y D S     +  SRSS S S S S   
Sbjct: 654 NIKETGSS-----SSYHKREKNSESDQSTYSKYSDRSSESSPRSRSRSSRSRSYSRSYTR 708

Query: 590 SREEKESKKEREEEFKTHHEMKEYSGFAGVSR 621
           SR    S           H   +YS  +  SR
Sbjct: 709 SRSLASSHSRSRSPSSRSHSRNKYSDHSQCSR 740



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 88/386 (22%), Positives = 148/386 (38%), Gaps = 69/386 (17%)

Query: 273 GSGSVGNGSSRYSPSQNSPIHHIPSRRSP---------AKTIAPQNAPRDESRGRSSFYP 323
           GS S  N SS    S  S + H  SRR           +K    + +  +E R + +  P
Sbjct: 197 GSDSSSNSSSSSESSSESELEHERSRRRKHKRRPKVKRSKKRRKEASSSEEPRNKHAMNP 256

Query: 324 DGGDQETAKTGKFLKSPPLHKNLDA---REKSTFREES----PLRIKMIASD----SHRP 372
            G  + +    K        +++D+   REK   R E     P    ++  D    +  P
Sbjct: 257 KGHSERSDTNEK--------RSVDSSAKREKPVVRPEEIPPVPENRFLLRRDMPVVTAEP 308

Query: 373 EVKLK-MAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSES 431
           E K+  +AP+    S++  S++K          S +K +   +I  H   P  S+S SES
Sbjct: 309 EPKIPDVAPIV---SDQKPSVSK----------SGRKIKGRGTIRYHT--PPRSRSCSES 353

Query: 432 FIQHIVSLVHHVKE--QYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRI------- 482
                     H KE  Q  ++      E+++   K ++  S+R     + +R        
Sbjct: 354 DDDDSSETPPHWKEEMQRLRAYRPPSGEKWSKGDKLSDPCSSRWDERSLSQRSRSWSYNG 413

Query: 483 ---DISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSK 539
              D+S +    H +   +E+  K + +KG K+  C          RR K+  K R    
Sbjct: 414 YYSDLSTARHSGHHKKRRKEKKVKHK-KKGKKQKHC----------RRHKQTKKRRILIP 462

Query: 540 GSRESSGS--RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESK 597
              ESS S  R+ + +    +  +S    S H  ++D S+S     S  + SSR+   SK
Sbjct: 463 SDIESSKSSTRRMKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSK 522

Query: 598 KEREEEFKTHHEMKEYSGFAGVSRPR 623
              +   +     +  S  +  SR R
Sbjct: 523 SHSQSYSRGSSRSRTASKSSSHSRSR 548



 Score = 39.3 bits (90), Expect = 0.013
 Identities = 124/680 (18%), Positives = 232/680 (34%), Gaps = 119/680 (17%)

Query: 7    RSHSSRSKSRSQSSSRS-RSRSHSRKKRYSSRSRSRTYSRSRSRDRMY--------SRDY 57
            R+H+ + K+R +  S+S R   HS+K+           + S+ + + Y        S   
Sbjct: 833  RTHNKQEKNRGEEKSKSERECPHSKKRTLKENLSDHLRNGSKPKRKNYAGSKWDSESNSE 892

Query: 58   RRDYRNNRGMRRPYGYRGRGRGYYQGGG--GRYHRGGYRPVWNRRHSRSPRRGRSRSRSP 115
            R   +N++    P   +  G             H        +  ++  P    +   S 
Sbjct: 893  RDVTKNSKNDSHPSSDKEEGEATSDSESEVSEIHIKVKPTTKSSTNTSLPDDNGAWKSSK 952

Query: 116  KRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSS--SPYSKSPVSKRRGSQEKQTKKAE--- 170
            +R S S       +  + R         S+ +    ++K    K +G ++K+ K  +   
Sbjct: 953  QRTSTSDSEGSCSNSENNRGKPQKHKHGSKENLKREHTKKVKEKLKGKKDKKHKAPKRKQ 1012

Query: 171  ----------GEPQEESPLKSKSQEEPKDTFEHDPSESI-DEFNKSSATSGDIWPGLSAY 219
                      GE +EE     +  +E K+    + +E+I D   K+  +S +   G    
Sbjct: 1013 AFHWQPPLEFGEEEEEEIDDKQVTQESKEKKVSENNETIKDNILKTEKSSEEDLSG---- 1068

Query: 220  DNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHS--HSIQHSPERSGSGSV 277
                   H    +++   Q +   D   LS   +A NT    +   +IQH  E     SV
Sbjct: 1069 ------KHDTVTVSSDLDQFTK--DDSKLSISPTALNTEENVACLQNIQHVEE-----SV 1115

Query: 278  GNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFL 337
             NG      + ++     P R SPAK                        +ET+  G   
Sbjct: 1116 PNGVEDVLQTDDNMEICTPDRSSPAKV-----------------------EETSPLGNAR 1152

Query: 338  KSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPA------S 391
               P   +++   K     E P + +++  +S   E K+ +  V   DS+  +      S
Sbjct: 1153 LDTP---DINIVLKQDMATEHP-QAEVVKQESSMSESKV-LGEVGKQDSSSASLASAGES 1207

Query: 392  LTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSA 451
              K  +   + ++ + K+ +      ++  P A+  TS +    +++ V  +K Q  +  
Sbjct: 1208 TGKKEVAEKSQINLIDKKWKPLQGVGNLAAPNAA--TSSAVEVKVLTTVPEMKPQGLRIE 1265

Query: 452  AMTLNE-----------------RFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTR 494
              + N+                 R    Q+++ +  T  +  +   R   SPS  R  + 
Sbjct: 1266 IKSKNKVRPGSLFDEVRKTARLNRRPRNQESSSDEQTPSRDDDSQSR---SPSRSRSKSE 1322

Query: 495  LAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKER-------SKERGDS----KGSRE 543
                 R           + R  ++  R     R + R       ++ R  S    K  R 
Sbjct: 1323 TKSRHRTRSVSYSHSRSRSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSSYRSYKSHRT 1382

Query: 544  SSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKE------SK 597
            SS SR +  +   +   +SY  DS + R +  SRS  S +     S            S 
Sbjct: 1383 SSRSRSRSSSYDPHSRSRSYTYDSYYSRSRSRSRSQRSDSYHRGRSYNRRSRSCRSYGSD 1442

Query: 598  KEREEEFKTHHEMKEYSGFA 617
             E +  +  H    E S ++
Sbjct: 1443 SESDRSYSHHRSPSESSRYS 1462


>gi|126723149 chromosome 19 open reading frame 29 [Homo sapiens]
          Length = 758

 Score = 70.9 bits (172), Expect = 4e-12
 Identities = 69/222 (31%), Positives = 94/222 (42%), Gaps = 31/222 (13%)

Query: 3   RSNSRSHSSRSKSR-SQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDY 61
           RS SRS   R + R SQS SRSRSRSH R      R+R R     R R R  SR+ R D 
Sbjct: 6   RSRSRSAGRRGRRRQSQSGSRSRSRSHGR------RNRRRREDEGRRRRRRRSRERRSDS 59

Query: 62  RNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVS 121
              R  R                 G   R   RP W   HSR    G S+S S + +S  
Sbjct: 60  EEERWQR----------------SGMRSRSPPRPKW---HSRD---GSSQSDSGEEQSRG 97

Query: 122 SQRSRSRSRRSYRSSRSPRSSSS--RSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPL 179
               R R  RS+  S S  SS+S  RS SP + +    ++ S +++ +  E   Q+E  +
Sbjct: 98  QWARRRRRARSWSPSSSASSSASPGRSQSPRAAAAALSQQQSLQERLRLREERKQQEELM 157

Query: 180 KSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDN 221
           K+    E K        E+ +   +     G+ + G +  DN
Sbjct: 158 KAFETPEEKRARRLAKKEAKERKKREKMGWGEEYMGYTNTDN 199



 Score = 34.7 bits (78), Expect = 0.33
 Identities = 39/132 (29%), Positives = 49/132 (37%), Gaps = 24/132 (18%)

Query: 62  RNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVS 121
           R+ R   R  G RGR R    G   R          +R H R  RR R      +RR   
Sbjct: 3   RDTRSRSRSAGRRGRRRQSQSGSRSR----------SRSHGRRNRRRREDEGRRRRR--- 49

Query: 122 SQRSRSRS--------RRSYRSSRSPRSSS--SRSSSPYSKSPVSKRRGSQEKQTKKAEG 171
            +RSR R         +RS   SRSP      SR  S  S S   + RG   ++ ++A  
Sbjct: 50  -RRSRERRSDSEEERWQRSGMRSRSPPRPKWHSRDGSSQSDSGEEQSRGQWARRRRRARS 108

Query: 172 EPQEESPLKSKS 183
                S   S S
Sbjct: 109 WSPSSSASSSAS 120



 Score = 31.2 bits (69), Expect = 3.7
 Identities = 35/122 (28%), Positives = 51/122 (41%), Gaps = 36/122 (29%)

Query: 526 RRRKERSKER-GDSKGSR-ESSGSRKQEKT-PKDYKEYKSYKDDS-------------KH 569
           RRR+ RS+ER  DS+  R + SG R +    PK +    S + DS             + 
Sbjct: 46  RRRRRRSRERRSDSEEERWQRSGMRSRSPPRPKWHSRDGSSQSDSGEEQSRGQWARRRRR 105

Query: 570 KREQDHSRSSSSSASPSSPSS--------------------REEKESKKEREEEFKTHHE 609
            R    S S+SSSASP    S                    REE++ ++E  + F+T  E
Sbjct: 106 ARSWSPSSSASSSASPGRSQSPRAAAAALSQQQSLQERLRLREERKQQEELMKAFETPEE 165

Query: 610 MK 611
            +
Sbjct: 166 KR 167


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.308    0.124    0.351 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,326,211
Number of Sequences: 37866
Number of extensions: 1828768
Number of successful extensions: 34103
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 436
Number of HSP's successfully gapped in prelim test: 1010
Number of HSP's that attempted gapping in prelim test: 13674
Number of HSP's gapped (non-prelim): 10423
length of query: 747
length of database: 18,247,518
effective HSP length: 110
effective length of query: 637
effective length of database: 14,082,258
effective search space: 8970398346
effective search space used: 8970398346
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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