BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|117938254 BCL2-associated transcription factor 1 isoform 3 [Homo sapiens] (747 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|117938254 BCL2-associated transcription factor 1 isoform 3 [H... 1513 0.0 gi|7661958 BCL2-associated transcription factor 1 isoform 1 [Hom... 838 0.0 gi|117938251 BCL2-associated transcription factor 1 isoform 2 [H... 677 0.0 gi|169218320 PREDICTED: similar to BCL2-associated transcription... 675 0.0 gi|239756568 PREDICTED: similar to BCL2-associated transcription... 664 0.0 gi|167234419 thyroid hormone receptor associated protein 3 [Homo... 367 e-101 gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 109 8e-24 gi|115511057 hypothetical protein LOC256643 [Homo sapiens] 103 4e-22 gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 96 9e-20 gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 94 6e-19 gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sap... 89 1e-17 gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sap... 89 1e-17 gi|133922600 splicing factor, arginine/serine-rich 16 [Homo sapi... 89 2e-17 gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 86 2e-16 gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 86 2e-16 gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] 81 4e-15 gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 80 5e-15 gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] 80 9e-15 gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] 80 9e-15 gi|15055543 splicing factor, arginine/serine-rich 2B [Homo sapiens] 79 1e-14 gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 79 2e-14 gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 76 1e-13 gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 76 1e-13 gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 76 1e-13 gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo s... 73 8e-13 gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 73 8e-13 gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens] 73 1e-12 gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens] 72 2e-12 gi|6631100 natural killer-tumor recognition sequence [Homo sapiens] 71 3e-12 gi|126723149 chromosome 19 open reading frame 29 [Homo sapiens] 71 4e-12 >gi|117938254 BCL2-associated transcription factor 1 isoform 3 [Homo sapiens] Length = 747 Score = 1513 bits (3916), Expect = 0.0 Identities = 747/747 (100%), Positives = 747/747 (100%) Query: 1 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD 60 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD Sbjct: 1 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD 60 Query: 61 YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 120 YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV Sbjct: 61 YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 120 Query: 121 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK 180 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK Sbjct: 121 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK 180 Query: 181 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS 240 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS Sbjct: 181 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS 240 Query: 241 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS 300 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS Sbjct: 241 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS 300 Query: 301 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKSPPLHKNLDAREKSTFREESPL 360 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKSPPLHKNLDAREKSTFREESPL Sbjct: 301 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKSPPLHKNLDAREKSTFREESPL 360 Query: 361 RIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIK 420 RIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIK Sbjct: 361 RIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIK 420 Query: 421 LPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHR 480 LPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHR Sbjct: 421 LPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHR 480 Query: 481 RIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKG 540 RIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKG Sbjct: 481 RIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKG 540 Query: 541 SRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKER 600 SRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKER Sbjct: 541 SRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKER 600 Query: 601 EEEFKTHHEMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEE 660 EEEFKTHHEMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEE Sbjct: 601 EEEFKTHHEMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEE 660 Query: 661 EWDPEYTPKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQ 720 EWDPEYTPKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQ Sbjct: 661 EWDPEYTPKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQ 720 Query: 721 GDGIVEDEEETMENNEEKKDRRKEEKE 747 GDGIVEDEEETMENNEEKKDRRKEEKE Sbjct: 721 GDGIVEDEEETMENNEEKKDRRKEEKE 747 >gi|7661958 BCL2-associated transcription factor 1 isoform 1 [Homo sapiens] Length = 920 Score = 838 bits (2165), Expect = 0.0 Identities = 467/740 (63%), Positives = 515/740 (69%), Gaps = 61/740 (8%) Query: 13 SKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNNRGMRRPYG 72 S+S S S + S HS K S S S +S RS Sbjct: 237 SQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERS------------------------ 272 Query: 73 YRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRS 132 G G G RY P+ + RSP + + +P R SR R S Sbjct: 273 ----GSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAP--------RDESRGRSS 320 Query: 133 YRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAE-GEPQEESPLKSKSQEEPKDTF 191 + + ++ KR +E + + G +++ K K E+ + Sbjct: 321 FYPDGGDQETAKTGK-------FLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEG 373 Query: 192 EHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTV 251 E + E++D F+ + G +++S + +S +T Sbjct: 374 EWEDQEALDYFSDKES-------GKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATA 426 Query: 252 HSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAP 311 S +NT + +++ + S G+ S + +N + T ++ Sbjct: 427 -SHRNTEEE---GLKYKSKVSLKGN--RESDGFREEKNYKLKETGYVVERPSTTKDKHKE 480 Query: 312 RDESRGRSSFYPDGGDQETAKTGK----FLKSPPLHKNLDAREKSTFREESPLRIKMIAS 367 D++ R + + E K+ K F SPPLHKNLDAREKSTFREESPLRIKMIAS Sbjct: 481 EDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIAS 540 Query: 368 DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS 427 DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS Sbjct: 541 DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS 600 Query: 428 TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS 487 TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS Sbjct: 601 TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS 660 Query: 488 TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS 547 TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS Sbjct: 661 TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS 720 Query: 548 RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH 607 RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH Sbjct: 721 RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH 780 Query: 608 HEMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYT 667 HEMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYT Sbjct: 781 HEMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYT 840 Query: 668 PKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVED 727 PKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVED Sbjct: 841 PKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVED 900 Query: 728 EEETMENNEEKKDRRKEEKE 747 EEETMENNEEKKDRRKEEKE Sbjct: 901 EEETMENNEEKKDRRKEEKE 920 Score = 686 bits (1769), Expect = 0.0 Identities = 338/338 (100%), Positives = 338/338 (100%) Query: 1 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD 60 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD Sbjct: 1 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD 60 Query: 61 YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 120 YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV Sbjct: 61 YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 120 Query: 121 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK 180 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK Sbjct: 121 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK 180 Query: 181 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS 240 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS Sbjct: 181 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS 240 Query: 241 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS 300 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS Sbjct: 241 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS 300 Query: 301 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLK 338 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLK Sbjct: 301 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLK 338 Score = 38.1 bits (87), Expect = 0.030 Identities = 42/197 (21%), Positives = 75/197 (38%), Gaps = 26/197 (13%) Query: 564 KDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFK---------THHEMKEYS 614 + +S+ + SRS SSS S S SR+++ S + R + + ++Y Sbjct: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYR 62 Query: 615 GFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEY--TPKSKK 672 G+ RP G RGR RG + G + + W+ + +P+ + Sbjct: 63 NNRGMRRPYGY------RGRGRGYYQG-------GGGRYHRGGYRPVWNRRHSRSPRRGR 109 Query: 673 YFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSP--KWTHDKYQGDGIVEDEEE 730 + V R R R +++ R + SSP K K +G + ++ Sbjct: 110 SRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKA 169 Query: 731 TMENNEEKKDRRKEEKE 747 E EE + K ++E Sbjct: 170 EGEPQEESPLKSKSQEE 186 Score = 38.1 bits (87), Expect = 0.030 Identities = 42/197 (21%), Positives = 75/197 (38%), Gaps = 26/197 (13%) Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYR 62 + +S+ + SRS SSS S S SR+++ S + R + + ++Y Sbjct: 737 KDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFK---------THHEMKEYS 787 Query: 63 NNRGMRRPYGY------RGRGRGYYQG-------GGGRYHRGGYRPVWNRRHSRSPRRGR 109 G+ RP G RGR RG + G + + W+ + +P+ + Sbjct: 788 GFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEY--TPKSKK 845 Query: 110 SRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKA 169 + V R R R +++ R + SSP K K +G + ++ Sbjct: 846 YFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSP--KWTHDKYQGDGIVEDEEE 903 Query: 170 EGEPQEESPLKSKSQEE 186 E EE + K ++E Sbjct: 904 TMENNEEKKDRRKEEKE 920 Score = 33.1 bits (74), Expect = 0.97 Identities = 43/187 (22%), Positives = 78/187 (41%), Gaps = 25/187 (13%) Query: 460 TSYQKATEEHSTRQKSPEIHRRIDISP-STLRKHTRLAGEERVFKEENQKGDKKLRCDSA 518 +S K+ + S+R +S R+ S S R ++R +R++ + ++ + R Sbjct: 10 SSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNNR---- 65 Query: 519 DLRHDIDRRRKERSKERG--------------DSKGSRESSGSRKQEKTPKDYKEYKSYK 564 +R R + R +G + + SR R + ++PK + S + Sbjct: 66 GMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKR-RSVSSQR 124 Query: 565 DDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKT---HHEMKEYSGFAGVSR 621 S+ +R SRS SS+S SS + SK+ +E +T E +E S S+ Sbjct: 125 SRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQ 184 Query: 622 --PRGTF 626 P+ TF Sbjct: 185 EEPKDTF 191 Score = 33.1 bits (74), Expect = 0.97 Identities = 43/187 (22%), Positives = 78/187 (41%), Gaps = 25/187 (13%) Query: 10 SSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNNR---- 65 +S K+ + S+R +S R+ S S R ++R +R++ + ++ + R Sbjct: 633 TSYQKATEEHSTRQKSPEIHRRIDISP-STLRKHTRLAGEERVFKEENQKGDKKLRCDSA 691 Query: 66 GMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKR-RSVSSQR 124 +R R + R +G + + SR R + ++PK + S + Sbjct: 692 DLRHDIDRRRKERSKERG--------------DSKGSRESSGSRKQEKTPKDYKEYKSYK 737 Query: 125 SRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQ 184 S+ +R SRS SS+S SS + SK+ +E +T E +E S S+ Sbjct: 738 DDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKT---HHEMKEYSGFAGVSR 794 Query: 185 EEPKDTF 191 P+ TF Sbjct: 795 --PRGTF 799 >gi|117938251 BCL2-associated transcription factor 1 isoform 2 [Homo sapiens] Length = 869 Score = 677 bits (1748), Expect = 0.0 Identities = 336/338 (99%), Positives = 336/338 (99%), Gaps = 2/338 (0%) Query: 1 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD 60 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRY RSRSRTYSRSRSRDRMYSRDYRRD Sbjct: 1 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRY--RSRSRTYSRSRSRDRMYSRDYRRD 58 Query: 61 YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 120 YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV Sbjct: 59 YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 118 Query: 121 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK 180 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK Sbjct: 119 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK 178 Query: 181 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS 240 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS Sbjct: 179 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS 238 Query: 241 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS 300 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS Sbjct: 239 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS 298 Query: 301 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLK 338 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLK Sbjct: 299 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLK 336 Score = 659 bits (1700), Expect = 0.0 Identities = 403/748 (53%), Positives = 452/748 (60%), Gaps = 126/748 (16%) Query: 13 SKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNNRGMRRPYG 72 S+S S S + S HS K S S S +S RS Sbjct: 235 SQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERS------------------------ 270 Query: 73 YRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRS 132 G G G RY P+ + RSP + + +P R SR R S Sbjct: 271 ----GSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAP--------RDESRGRSS 318 Query: 133 YRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAE-GEPQEESPLKSKSQEEPKDTF 191 + + ++ KR +E + + G +++ K K E+ + Sbjct: 319 FYPDGGDQETAKTGK-------FLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEG 371 Query: 192 EHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTV 251 E + E++D F+ + G +++S + +S +T Sbjct: 372 EWEDQEALDYFSDKES-------GKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATA 424 Query: 252 HSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAP 311 S +NT + +++ + S G+ S + +N + T ++ Sbjct: 425 -SHRNTEEE---GLKYKSKVSLKGN--RESDGFREEKNYKLKETGYVVERPSTTKDKHKE 478 Query: 312 RDESRGRSSFYPDGGDQETAKTGK----FLKSPPLHKNLDAREKSTFREESPLRIKMIAS 367 D++ R + + E K+ K F SPPLHKNLDAREKSTFREESPLRIKMIAS Sbjct: 479 EDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIAS 538 Query: 368 DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS 427 DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS Sbjct: 539 DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS 598 Query: 428 TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS 487 TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS Sbjct: 599 TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS 658 Query: 488 TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS 547 TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS Sbjct: 659 TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS 718 Query: 548 RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH 607 RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH Sbjct: 719 RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH 778 Query: 608 HEMKEYSGFAGVSRPRGTFFRIRG--------RGRARGVFAGTNTGPNNSNTTFQKRPKE 659 HEMKEYSGFAGVSRPRGTF R RGR RG F Sbjct: 779 HEMKEYSGFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTF-------------------- 818 Query: 660 EEWDPEYTPKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKY 719 +RGR GRFNFKKSGSSPKWTHDKY Sbjct: 819 ----------------------------QRGR---------GRFNFKKSGSSPKWTHDKY 841 Query: 720 QGDGIVEDEEETMENNEEKKDRRKEEKE 747 QGDGIVEDEEETMENNEEKKDRRKEEKE Sbjct: 842 QGDGIVEDEEETMENNEEKKDRRKEEKE 869 Score = 42.7 bits (99), Expect = 0.001 Identities = 31/111 (27%), Positives = 48/111 (43%), Gaps = 25/111 (22%) Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYR 62 + +S+ + SRS SSS S S SR+++ S + R + + ++Y Sbjct: 735 KDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFK---------THHEMKEYS 785 Query: 63 NNRGMRRPYG--------------YRGRGRGYYQGGGGRYH--RGGYRPVW 97 G+ RP G RGRGRG +Q G GR++ + G P W Sbjct: 786 GFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKW 836 Score = 42.0 bits (97), Expect = 0.002 Identities = 52/225 (23%), Positives = 92/225 (40%), Gaps = 26/225 (11%) Query: 10 SSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNNR---- 65 +S K+ + S+R +S R+ S S R ++R +R++ + ++ + R Sbjct: 631 TSYQKATEEHSTRQKSPEIHRRIDISP-STLRKHTRLAGEERVFKEENQKGDKKLRCDSA 689 Query: 66 GMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKR-RSVSSQR 124 +R R + R +G + + SR R + ++PK + S + Sbjct: 690 DLRHDIDRRRKERSKERG--------------DSKGSRESSGSRKQEKTPKDYKEYKSYK 735 Query: 125 SRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQ 184 S+ +R SRS SS+S SS + SK+ +E +T E +E S S+ Sbjct: 736 DDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKT---HHEMKEYSGFAGVSR 792 Query: 185 EEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSP 229 P+ TF D + +D + K G G + N +S SP Sbjct: 793 --PRGTFHDDRDDGVDYWAKRGRGRGTFQRGRGRF-NFKKSGSSP 834 Score = 36.2 bits (82), Expect = 0.11 Identities = 41/195 (21%), Positives = 74/195 (37%), Gaps = 24/195 (12%) Query: 564 KDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKER-------EEEFKTHHEMKEYSGF 616 + +S+ + SRS SSS S S SR+++ + R + + ++Y Sbjct: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNN 62 Query: 617 AGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEY--TPKSKKYF 674 G+ RP G RGR RG + G + + W+ + +P+ + Sbjct: 63 RGMRRPYGY------RGRGRGYYQG-------GGGRYHRGGYRPVWNRRHSRSPRRGRSR 109 Query: 675 LHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSP--KWTHDKYQGDGIVEDEEETM 732 + V R R R +++ R + SSP K K +G + ++ Sbjct: 110 SRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEG 169 Query: 733 ENNEEKKDRRKEEKE 747 E EE + K ++E Sbjct: 170 EPQEESPLKSKSQEE 184 Score = 33.5 bits (75), Expect = 0.74 Identities = 43/186 (23%), Positives = 77/186 (41%), Gaps = 25/186 (13%) Query: 460 TSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSAD 519 +S K+ + S+R +S H R S R ++R +R++ + ++ + R Sbjct: 10 SSRSKSRSQSSSRSRSRS-HSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNNR----G 64 Query: 520 LRHDIDRRRKERSKERG--------------DSKGSRESSGSRKQEKTPKDYKEYKSYKD 565 +R R + R +G + + SR R + ++PK + S + Sbjct: 65 MRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKR-RSVSSQRS 123 Query: 566 DSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKT---HHEMKEYSGFAGVSR- 621 S+ +R SRS SS+S SS + SK+ +E +T E +E S S+ Sbjct: 124 RSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQE 183 Query: 622 -PRGTF 626 P+ TF Sbjct: 184 EPKDTF 189 Score = 30.4 bits (67), Expect = 6.3 Identities = 25/99 (25%), Positives = 41/99 (41%), Gaps = 20/99 (20%) Query: 631 GRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYTPKSKKYFLHDDRDD--GVDY--- 685 GR +R + ++ + S ++ + R + Y +S+ Y RD DY Sbjct: 2 GRSNSR---SHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRD 58 Query: 686 ----------WAKRGRGRGTFQRGRGRFNFKKSGSSPKW 714 + RGRGRG +Q G GR++ + G P W Sbjct: 59 YRNNRGMRRPYGYRGRGRGYYQGGGGRYH--RGGYRPVW 95 >gi|169218320 PREDICTED: similar to BCL2-associated transcription factor 1 isoform 2 [Homo sapiens] Length = 869 Score = 675 bits (1742), Expect = 0.0 Identities = 335/338 (99%), Positives = 335/338 (99%), Gaps = 2/338 (0%) Query: 1 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD 60 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRY RSRSRTYSRSRSRDRMYSRDYRRD Sbjct: 1 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRY--RSRSRTYSRSRSRDRMYSRDYRRD 58 Query: 61 YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 120 YRNNR MRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV Sbjct: 59 YRNNRAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 118 Query: 121 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK 180 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK Sbjct: 119 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK 178 Query: 181 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS 240 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS Sbjct: 179 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS 238 Query: 241 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS 300 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS Sbjct: 239 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS 298 Query: 301 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLK 338 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLK Sbjct: 299 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLK 336 Score = 643 bits (1658), Expect = 0.0 Identities = 397/749 (53%), Positives = 449/749 (59%), Gaps = 128/749 (17%) Query: 13 SKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNNRGMRRPYG 72 S+S S S + S HS K S S S +S RS Sbjct: 235 SQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERS------------------------ 270 Query: 73 YRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRS 132 G G G RY P+ + RSP + + +P R SR R S Sbjct: 271 ----GSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAP--------RDESRGRSS 318 Query: 133 YRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAE-GEPQEESPLKSKSQEEPKDTF 191 + + ++ KR +E + + G +++ K K E+ + Sbjct: 319 FYPDGGDQETAKTGK-------FLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEG 371 Query: 192 EHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTV 251 E + E++D F+ + G +++S + +S +T Sbjct: 372 EWEDQEALDYFSDKES-------GKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATA 424 Query: 252 HSAKNTPSQHSHSIQHSPERSGSGS-VGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNA 310 S +NT + +++ + S G+ +G ++ ++ R S K ++ Sbjct: 425 -SHRNTEEE---GLKYKSKVSLKGNRESDGFREEKNDKHKETGYVVERPSTTKD---KHK 477 Query: 311 PRDESRGRSSFYPDGGDQETAKTGK----FLKSPPLHKNLDAREKSTFREESPLRIKMIA 366 D++ R + + E K+ K F SPPLHKNLDAREKSTFREESPLRIKMIA Sbjct: 478 EEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIA 537 Query: 367 SDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASK 426 SDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASK Sbjct: 538 SDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASK 597 Query: 427 STSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISP 486 STSESFIQHIVSLVHHVKEQYFKSAAMTL+ERFTSYQKATEEHSTRQKSPEIHRRIDISP Sbjct: 598 STSESFIQHIVSLVHHVKEQYFKSAAMTLSERFTSYQKATEEHSTRQKSPEIHRRIDISP 657 Query: 487 STLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSG 546 STLRK TRLAGEERVFKEENQKGDKKLRCDSADLRHDID RRKERSKERGDSKGSRES G Sbjct: 658 STLRKDTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDHRRKERSKERGDSKGSRESRG 717 Query: 547 SRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKT 606 SRKQEKTPKDYKEYKSYKDDSKHKREQDHS SSSSSASPSSPSSREEKESKKEREEEFKT Sbjct: 718 SRKQEKTPKDYKEYKSYKDDSKHKREQDHSLSSSSSASPSSPSSREEKESKKEREEEFKT 777 Query: 607 HHEMKEYSGFAGVSRPRGTFFRIRG--------RGRARGVFAGTNTGPNNSNTTFQKRPK 658 HHEMKEYSGFAGVSRPRGTF R RGR RG F Sbjct: 778 HHEMKEYSGFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTF------------------- 818 Query: 659 EEEWDPEYTPKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDK 718 +RGR GRFNFKKSGSSPKW HDK Sbjct: 819 -----------------------------QRGR---------GRFNFKKSGSSPKWNHDK 840 Query: 719 YQGDGIVEDEEETMENNEEKKDRRKEEKE 747 YQGDGIVEDEEETMENNEEKKDR KEEKE Sbjct: 841 YQGDGIVEDEEETMENNEEKKDRCKEEKE 869 Score = 42.4 bits (98), Expect = 0.002 Identities = 31/112 (27%), Positives = 47/112 (41%), Gaps = 25/112 (22%) Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYR 62 + +S+ + S S SSS S S SR+++ S + R + ++Y Sbjct: 735 KDDSKHKREQDHSLSSSSSASPSSPSSREEKESKKEREEEFKTHHEM---------KEYS 785 Query: 63 NNRGMRRPYGY--------------RGRGRGYYQGGGGRYH--RGGYRPVWN 98 G+ RP G RGRGRG +Q G GR++ + G P WN Sbjct: 786 GFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWN 837 Score = 42.0 bits (97), Expect = 0.002 Identities = 53/230 (23%), Positives = 95/230 (41%), Gaps = 28/230 (12%) Query: 6 SRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNNR 65 S +S K+ + S+R +S R+ S S R +R +R++ + ++ + R Sbjct: 627 SERFTSYQKATEEHSTRQKSPEIHRRIDISP-STLRKDTRLAGEERVFKEENQKGDKKLR 685 Query: 66 ----GMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKR-RSV 120 +R +R + R +G + + SR R R + ++PK + Sbjct: 686 CDSADLRHDIDHRRKERSKERG--------------DSKGSRESRGSRKQEKTPKDYKEY 731 Query: 121 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTK-KAEGEPQEESPL 179 S + S+ +R S S SS S+SP S S ++ +E++ + K E +E S Sbjct: 732 KSYKDDSKHKREQDHSLS----SSSSASPSSPSSREEKESKKEREEEFKTHHEMKEYSGF 787 Query: 180 KSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSP 229 S+ P+ TF D + +D + K G G + N +S SP Sbjct: 788 AGVSR--PRGTFHDDRDDGVDYWAKRGRGRGTFQRGRGRF-NFKKSGSSP 834 Score = 33.9 bits (76), Expect = 0.57 Identities = 40/195 (20%), Positives = 73/195 (37%), Gaps = 24/195 (12%) Query: 564 KDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKER-------EEEFKTHHEMKEYSGF 616 + +S+ + SRS SSS S S SR+++ + R + + ++Y Sbjct: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNN 62 Query: 617 AGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEY--TPKSKKYF 674 + RP G RGR RG + G + + W+ + +P+ + Sbjct: 63 RAMRRPYGY------RGRGRGYYQG-------GGGRYHRGGYRPVWNRRHSRSPRRGRSR 109 Query: 675 LHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSP--KWTHDKYQGDGIVEDEEETM 732 + V R R R +++ R + SSP K K +G + ++ Sbjct: 110 SRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEG 169 Query: 733 ENNEEKKDRRKEEKE 747 E EE + K ++E Sbjct: 170 EPQEESPLKSKSQEE 184 Score = 33.9 bits (76), Expect = 0.57 Identities = 43/186 (23%), Positives = 77/186 (41%), Gaps = 25/186 (13%) Query: 460 TSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSAD 519 +S K+ + S+R +S H R S R ++R +R++ + ++ + R Sbjct: 10 SSRSKSRSQSSSRSRSRS-HSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNNRA---- 64 Query: 520 LRHDIDRRRKERSKERG--------------DSKGSRESSGSRKQEKTPKDYKEYKSYKD 565 +R R + R +G + + SR R + ++PK + S + Sbjct: 65 MRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKR-RSVSSQRS 123 Query: 566 DSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKT---HHEMKEYSGFAGVSR- 621 S+ +R SRS SS+S SS + SK+ +E +T E +E S S+ Sbjct: 124 RSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQE 183 Query: 622 -PRGTF 626 P+ TF Sbjct: 184 EPKDTF 189 Score = 30.4 bits (67), Expect = 6.3 Identities = 25/99 (25%), Positives = 41/99 (41%), Gaps = 20/99 (20%) Query: 631 GRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYTPKSKKYFLHDDRDD--GVDY--- 685 GR +R + ++ + S ++ + R + Y +S+ Y RD DY Sbjct: 2 GRSNSR---SHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRD 58 Query: 686 ----------WAKRGRGRGTFQRGRGRFNFKKSGSSPKW 714 + RGRGRG +Q G GR++ + G P W Sbjct: 59 YRNNRAMRRPYGYRGRGRGYYQGGGGRYH--RGGYRPVW 95 >gi|239756568 PREDICTED: similar to BCL2-associated transcription factor 1 [Homo sapiens] Length = 869 Score = 664 bits (1712), Expect = 0.0 Identities = 331/338 (97%), Positives = 331/338 (97%), Gaps = 2/338 (0%) Query: 1 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD 60 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRY RSRSRTYSRSRSRDRMYSRDYRRD Sbjct: 1 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRY--RSRSRTYSRSRSRDRMYSRDYRRD 58 Query: 61 YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 120 YRNNR MRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV Sbjct: 59 YRNNRAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 118 Query: 121 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK 180 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGE QEESPLK Sbjct: 119 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGELQEESPLK 178 Query: 181 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS 240 SKSQEEPKDTFEHD SESIDEFNKSSAT GDIWPGLSAYD SPRSPHSPSPIATPPSQSS Sbjct: 179 SKSQEEPKDTFEHDSSESIDEFNKSSATCGDIWPGLSAYDXSPRSPHSPSPIATPPSQSS 238 Query: 241 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS 300 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS Sbjct: 239 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS 298 Query: 301 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLK 338 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLK Sbjct: 299 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLK 336 Score = 643 bits (1658), Expect = 0.0 Identities = 397/749 (53%), Positives = 449/749 (59%), Gaps = 128/749 (17%) Query: 13 SKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNNRGMRRPYG 72 S+S S S + S HS K S S S +S RS Sbjct: 235 SQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERS------------------------ 270 Query: 73 YRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRS 132 G G G RY P+ + RSP + + +P R SR R S Sbjct: 271 ----GSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAP--------RDESRGRSS 318 Query: 133 YRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAE-GEPQEESPLKSKSQEEPKDTF 191 + + ++ KR +E + + G +++ K K E+ + Sbjct: 319 FYPDGGDQETAKTGK-------FLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEG 371 Query: 192 EHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTV 251 E + E++D F+ + G +++S + +S +T Sbjct: 372 EWEDQEALDYFSDKES-------GKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATA 424 Query: 252 HSAKNTPSQHSHSIQHSPERSGSGS-VGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNA 310 S +NT + +++ + S G+ +G ++ ++ R S K ++ Sbjct: 425 -SHRNTEEE---GLKYKSKVSLKGNRESDGFREEKNDKHKETGYVVERPSTTKD---KHK 477 Query: 311 PRDESRGRSSFYPDGGDQETAKTGK----FLKSPPLHKNLDAREKSTFREESPLRIKMIA 366 D++ R + + E K+ K F SPPLHKNLDAREKSTFREESPLRIKMIA Sbjct: 478 EEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIA 537 Query: 367 SDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASK 426 SDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASK Sbjct: 538 SDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASK 597 Query: 427 STSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISP 486 STSESFIQHIVSLVHHVKEQYFKSAAMTL+ERFTSYQKATEEHSTRQKSPEIHRRIDISP Sbjct: 598 STSESFIQHIVSLVHHVKEQYFKSAAMTLSERFTSYQKATEEHSTRQKSPEIHRRIDISP 657 Query: 487 STLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSG 546 STLRK TRLAGEERVFKEENQKGDKKLRCDSADLRHDID RRKERSKERGDSKGSRES G Sbjct: 658 STLRKDTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDHRRKERSKERGDSKGSRESRG 717 Query: 547 SRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKT 606 SRKQEKTPKDYKEYKSYKDDSKHKREQDHS SSSSSASPSSPSSREEKESKKEREEEFKT Sbjct: 718 SRKQEKTPKDYKEYKSYKDDSKHKREQDHSLSSSSSASPSSPSSREEKESKKEREEEFKT 777 Query: 607 HHEMKEYSGFAGVSRPRGTFFRIRG--------RGRARGVFAGTNTGPNNSNTTFQKRPK 658 HHEMKEYSGFAGVSRPRGTF R RGR RG F Sbjct: 778 HHEMKEYSGFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTF------------------- 818 Query: 659 EEEWDPEYTPKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDK 718 +RGR GRFNFKKSGSSPKW HDK Sbjct: 819 -----------------------------QRGR---------GRFNFKKSGSSPKWNHDK 840 Query: 719 YQGDGIVEDEEETMENNEEKKDRRKEEKE 747 YQGDGIVEDEEETMENNEEKKDR KEEKE Sbjct: 841 YQGDGIVEDEEETMENNEEKKDRCKEEKE 869 Score = 42.4 bits (98), Expect = 0.002 Identities = 31/112 (27%), Positives = 47/112 (41%), Gaps = 25/112 (22%) Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYR 62 + +S+ + S S SSS S S SR+++ S + R + ++Y Sbjct: 735 KDDSKHKREQDHSLSSSSSASPSSPSSREEKESKKEREEEFKTHHEM---------KEYS 785 Query: 63 NNRGMRRPYGY--------------RGRGRGYYQGGGGRYH--RGGYRPVWN 98 G+ RP G RGRGRG +Q G GR++ + G P WN Sbjct: 786 GFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWN 837 Score = 42.0 bits (97), Expect = 0.002 Identities = 53/230 (23%), Positives = 95/230 (41%), Gaps = 28/230 (12%) Query: 6 SRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNNR 65 S +S K+ + S+R +S R+ S S R +R +R++ + ++ + R Sbjct: 627 SERFTSYQKATEEHSTRQKSPEIHRRIDISP-STLRKDTRLAGEERVFKEENQKGDKKLR 685 Query: 66 ----GMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKR-RSV 120 +R +R + R +G + + SR R R + ++PK + Sbjct: 686 CDSADLRHDIDHRRKERSKERG--------------DSKGSRESRGSRKQEKTPKDYKEY 731 Query: 121 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTK-KAEGEPQEESPL 179 S + S+ +R S S SS S+SP S S ++ +E++ + K E +E S Sbjct: 732 KSYKDDSKHKREQDHSLS----SSSSASPSSPSSREEKESKKEREEEFKTHHEMKEYSGF 787 Query: 180 KSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSP 229 S+ P+ TF D + +D + K G G + N +S SP Sbjct: 788 AGVSR--PRGTFHDDRDDGVDYWAKRGRGRGTFQRGRGRF-NFKKSGSSP 834 Score = 35.4 bits (80), Expect = 0.19 Identities = 43/186 (23%), Positives = 78/186 (41%), Gaps = 25/186 (13%) Query: 460 TSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSAD 519 +S K+ + S+R +S H R S R ++R +R++ + ++ + R Sbjct: 10 SSRSKSRSQSSSRSRSRS-HSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNNRA---- 64 Query: 520 LRHDIDRRRKERSKERG--------------DSKGSRESSGSRKQEKTPKDYKEYKSYKD 565 +R R + R +G + + SR R + ++PK + S + Sbjct: 65 MRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKR-RSVSSQRS 123 Query: 566 DSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKT---HHEMKEYSGFAGVSR- 621 S+ +R SRS SS+S SS + SK+ +E +T E++E S S+ Sbjct: 124 RSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGELQEESPLKSKSQE 183 Query: 622 -PRGTF 626 P+ TF Sbjct: 184 EPKDTF 189 Score = 33.5 bits (75), Expect = 0.74 Identities = 40/195 (20%), Positives = 73/195 (37%), Gaps = 24/195 (12%) Query: 564 KDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKER-------EEEFKTHHEMKEYSGF 616 + +S+ + SRS SSS S S SR+++ + R + + ++Y Sbjct: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNN 62 Query: 617 AGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEY--TPKSKKYF 674 + RP G RGR RG + G + + W+ + +P+ + Sbjct: 63 RAMRRPYGY------RGRGRGYYQG-------GGGRYHRGGYRPVWNRRHSRSPRRGRSR 109 Query: 675 LHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSP--KWTHDKYQGDGIVEDEEETM 732 + V R R R +++ R + SSP K K +G + ++ Sbjct: 110 SRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEG 169 Query: 733 ENNEEKKDRRKEEKE 747 E EE + K ++E Sbjct: 170 ELQEESPLKSKSQEE 184 Score = 30.4 bits (67), Expect = 6.3 Identities = 25/99 (25%), Positives = 41/99 (41%), Gaps = 20/99 (20%) Query: 631 GRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYTPKSKKYFLHDDRDD--GVDY--- 685 GR +R + ++ + S ++ + R + Y +S+ Y RD DY Sbjct: 2 GRSNSR---SHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRD 58 Query: 686 ----------WAKRGRGRGTFQRGRGRFNFKKSGSSPKW 714 + RGRGRG +Q G GR++ + G P W Sbjct: 59 YRNNRAMRRPYGYRGRGRGYYQGGGGRYH--RGGYRPVW 95 >gi|167234419 thyroid hormone receptor associated protein 3 [Homo sapiens] Length = 955 Score = 367 bits (942), Expect = e-101 Identities = 297/834 (35%), Positives = 396/834 (47%), Gaps = 106/834 (12%) Query: 2 GRSNSRSHSSRSKS-RSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD 60 GRS SRS RS S RS+S SR+ +S S + R SS SRS S + SR R ++ Sbjct: 123 GRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRS---SSNHSRVESSKRKSAKE 179 Query: 61 YRNNRGMRRPYGYRGRGRG------YYQGG---------------------GGRYHRGGY 93 +++ RP G +G + GG G Sbjct: 180 KKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASRASAV 239 Query: 94 RPVWNRRHS--------------RSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSS--R 137 + R S RSPR SP S S S S Y+S + Sbjct: 240 SELSPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSGAGYQSGTHQ 299 Query: 138 SPRSSSSRSSSPYSKSPVSKRR-------GSQEKQTKKAEGEP-------QEESPLKSKS 183 S S SP KSPV K GS +K+ A G +E+ K Sbjct: 300 GQFDHGSGSLSPSKKSPVGKSPPSTGSTYGSSQKEESAASGGAAYTKRYLEEQKTENGKD 359 Query: 184 QEEPKDTFEHDPSESIDEFNKSSATSG----DIWPGLSAYDNSPRSPHSPSPIATPPSQS 239 +E+ + + + + F+ + G D + + + R SP Sbjct: 360 KEQKQTNTDKEKIKEKGSFSDTGLGDGKMKSDSFAPKTDSEKPFRGSQSPKRYKLRDDFE 419 Query: 240 SSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVG---NGSSRYSPSQNSPIHHIP 296 +D K+ S + S +G N S ++ P Sbjct: 420 KKMADFHKEEMDDQDKDKAKGRKESEFDDEPKFMSKVIGANKNQEEEKSGKWEGLVYAPP 479 Query: 297 SRRSPAKT--IAPQNAP---RDESRGRSS------FYPDGGDQETAKTGKFLKS--PPLH 343 + KT + ++ P + E RG+ S F P+ + TA KS PP Sbjct: 480 GKEKQRKTEELEEESFPERSKKEDRGKRSEGGHRGFVPEKNFRVTAYKAVQEKSSSPPPR 539 Query: 344 KNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLV 403 K ++R+K + + P K S + +V ++M D + L ++R L LV Sbjct: 540 KTSESRDKLGAKGDFPTG-KSSFSITREAQVNVRMDSFDEDLARPSGLLAQERKLCRDLV 598 Query: 404 HSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQ 463 HS KKEQEFRSIF HI+ Q+ +S SE F QHIV++VHHVKE +F S+ MTL+ERFT Y Sbjct: 599 HSNKKEQEFRSIFQHIQSAQSQRSPSELFAQHIVTIVHHVKEHHFGSSGMTLHERFTKYL 658 Query: 464 K--ATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLR 521 K +E + +KSPEIHRRIDISPST RKH E + +E K + K + D DLR Sbjct: 659 KRGTEQEAAKNKKSPEIHRRIDISPSTFRKHGLAHDEMKSPREPGYKAEGKYKDDPVDLR 718 Query: 522 HDIDRRRK--ERSKERGDSK---GSRESSGSRKQ--EKTPKDYKEYKSYKDDSKHKREQD 574 DI+RR+K ER +RG S+ SR+SS SR++ EKT K +K K K KH+R +D Sbjct: 719 LDIERRKKHKERDLKRGKSRESVDSRDSSHSRERSAEKTEKTHKGSKKQK---KHRRARD 775 Query: 575 HSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEM-----KEYSGFA--GVSRPRGTF- 626 SRSSSSS+ S EE + E EE T + K++ G + G R RGTF Sbjct: 776 RSRSSSSSSQSSHSYKAEEYTEETEEREESTTGFDKSRLGTKDFVGPSERGGGRARGTFQ 835 Query: 627 FRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYTPKSKKYFLHDDRD-DGVDY 685 FR RGRG RG ++G N NNSN FQKR +EEEWDPEYTPKSKKY+LHDDR+ +G D Sbjct: 836 FRARGRGWGRGNYSGNNN--NNSNNDFQKRNREEEWDPEYTPKSKKYYLHDDREGEGSDK 893 Query: 686 WAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQG-DGIVEDEEETMENNEEK 738 W RGRGRG F RGRGRF F+KS +SPKW HDK+ G +G +ED+E EN EEK Sbjct: 894 WVSRGRGRGAFPRGRGRFMFRKSSTSPKWAHDKFSGEEGEIEDDESGTENREEK 947 Score = 189 bits (479), Expect = 1e-47 Identities = 195/639 (30%), Positives = 301/639 (47%), Gaps = 73/639 (11%) Query: 2 GRSNSRSHS-SRSKSRSQSSSRSRSRS--HSRKKRYSSRSRSRTYSRSRSRDRMYSRDYR 58 G +SRS S SRS+SRS S SRSRSRS SRK+R SSRSRSR+YS + +R+R + R Y+ Sbjct: 10 GSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAHNRERNHPRVYQ 69 Query: 59 -RDYR-NNRGMRRPYGYRGRGRGYYQGGGGRYHRGG---YRPVW-NRRHSRSPRRGRSRS 112 RD+R +NRG RRPY +RGR RG+Y G+Y+RGG YR W N R + SPRRGRSRS Sbjct: 70 NRDFRGHNRGYRRPYYFRGRNRGFYP--WGQYNRGGYGNYRSNWQNYRQAYSPRRGRSRS 127 Query: 113 RSPKRRSVSSQRSRSRSRRSYRSS--RSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAE 170 RSPKRRS S RSRS SR S +SS RS RSSSSRSSS +S+ SKR+ ++EK++ + Sbjct: 128 RSPKRRS-PSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAKEKKSSSKD 186 Query: 171 GEPQEESPLKSKSQEEPKDTF------EHDPSESIDEFNKSSATSGDIWPGLSAYDNSP- 223 P + + ++ E + TF + SES + ++ +G + + SP Sbjct: 187 SRPSQAAG-DNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASRASAVSELSPR 245 Query: 224 -RSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGS--GSVGNG 280 RSP SP+ + + S +P+ +T S + +SG+ G +G Sbjct: 246 ERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSGAGYQSGTHQGQFDHG 305 Query: 281 SSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKSP 340 S SPS+ SP+ +SP T + + + E S GG A T ++L+ Sbjct: 306 SGSLSPSKKSPV-----GKSPPSTGSTYGSSQKEESAAS-----GG---AAYTKRYLEEQ 352 Query: 341 PLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKM-APVPLDDSNRPASLTKDRLLA 399 D +K T ++ ++ K SD+ + K+K + P DS +P ++ Sbjct: 353 KTENGKDKEQKQTNTDKEKIKEKGSFSDTGLGDGKMKSDSFAPKTDSEKPFRGSQS---- 408 Query: 400 STLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERF 459 K + R F+ K+ K + + K + K + +F Sbjct: 409 -------PKRYKLRDDFEK-KMADFHKEEMDDQDKD--------KAKGRKESEFDDEPKF 452 Query: 460 TSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSAD 519 S ++ +KS + + P ++ EE F E ++K D+ R + Sbjct: 453 MSKVIGANKNQEEEKSGKWEGLVYAPPGKEKQRKTEELEEESFPERSKKEDRGKRSEGGH 512 Query: 520 LRHDIDRRRK----ERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDH 575 ++ + + +E+ S R++S SR + D+ KS S + Q + Sbjct: 513 RGFVPEKNFRVTAYKAVQEKSSSPPPRKTSESRDKLGAKGDFPTGKS--SFSITREAQVN 570 Query: 576 SRSSSSSASPSSPSSREEKESK--------KEREEEFKT 606 R S + PS +E K ++E+EF++ Sbjct: 571 VRMDSFDEDLARPSGLLAQERKLCRDLVHSNKKEQEFRS 609 Score = 38.9 bits (89), Expect = 0.018 Identities = 46/195 (23%), Positives = 73/195 (37%), Gaps = 13/195 (6%) Query: 4 SNSRSHSSRSKSRSQSSSRSRSRSHSRK-KRYSSRSRSRTYSRSR-SRDRMYSRDYRRDY 61 S + R++ RS+SSS S SHS K + Y+ + R S + + R+ ++D+ Sbjct: 764 SKKQKKHRRARDRSRSSSSSSQSSHSYKAEEYTEETEEREESTTGFDKSRLGTKDFVGPS 823 Query: 62 RNNRGMRR-PYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 120 G R + +R RGRG+ G G Y N ++ +R R P+ Sbjct: 824 ERGGGRARGTFQFRARGRGW---GRGNYSGNNN----NNSNNDFQKRNREEEWDPEYTPK 876 Query: 121 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQ--TKKAEGEPQE-ES 177 S + R S + R + P + R+ S + K GE E E Sbjct: 877 SKKYYLHDDREGEGSDKWVSRGRGRGAFPRGRGRFMFRKSSTSPKWAHDKFSGEEGEIED 936 Query: 178 PLKSKSQEEPKDTFE 192 E KD + Sbjct: 937 DESGTENREEKDNIQ 951 Score = 35.8 bits (81), Expect = 0.15 Identities = 76/364 (20%), Positives = 120/364 (32%), Gaps = 63/364 (17%) Query: 424 ASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRID 483 AS+S S SF + S + ++ R SY A H+ + P +++ D Sbjct: 19 ASRSRSRSFSK---SRSRSRSLSRSRKRRLSSRSRSRSYSPA---HNRERNHPRVYQNRD 72 Query: 484 ISPST--LRKHTRLAGEERVFK---EENQKGDKKLRCDSADLRHDIDRRRKERSKERGDS 538 R+ G R F + N+ G R + + R RR RS+ R Sbjct: 73 FRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQAYSPRRG-RSRSRSPK 131 Query: 539 KGS---RESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKE 595 + S R S SR +K+ D + S + +HSR SS + K+ Sbjct: 132 RRSPSPRSRSHSRNSDKSSSDRS-----RRSSSSRSSSNHSRVESSKRKSAKEKKSSSKD 186 Query: 596 SKKEREEEFKTHHEMKEYSGFAGVSR-----------PRGTFFRIRGRGRARGVFAGTNT 644 S+ + E KE + G S+ P T+ G G A A + Sbjct: 187 SRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATY----GTGSASRASAVSEL 242 Query: 645 GPNNSNTTF----------QKRPKEEEWDPEYTPKSKKYFLHDDRDDGVDYWAKRGRGRG 694 P + ++ P+ P S + G Y + G +G Sbjct: 243 SPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSGAGY--QSGTHQG 300 Query: 695 TFQRGRGRFNFKKS---GSSPKWTHDKYQGDGIVED-------------EEETMENNEEK 738 F G G + K G SP T Y E EE+ EN ++K Sbjct: 301 QFDHGSGSLSPSKKSPVGKSPPSTGSTYGSSQKEESAASGGAAYTKRYLEEQKTENGKDK 360 Query: 739 KDRR 742 + ++ Sbjct: 361 EQKQ 364 Score = 30.0 bits (66), Expect = 8.2 Identities = 45/218 (20%), Positives = 74/218 (33%), Gaps = 38/218 (17%) Query: 564 KDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKER-------------EEEFKTHHEM 610 K S+ R + SRS S S S S SR S+K R + H + Sbjct: 8 KSGSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAHNRERNHPRV 67 Query: 611 KEYSGFAGVSRPRGTFFRIRGRGRA--------RGVFAGTNTGPNNSNTTFQ-KRPKEEE 661 + F G +R + RGR R RG + + N + +R + Sbjct: 68 YQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQAYSPRRGRSRS 127 Query: 662 WDPEY---TPKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSG--------- 709 P+ +P+S+ + + D+ D + R + R + +KS Sbjct: 128 RSPKRRSPSPRSRSHSRNSDKSSS-DRSRRSSSSRSSSNHSRVESSKRKSAKEKKSSSKD 186 Query: 710 SSPKWTHDKYQGDGIVEDEEETMENNEEKKDRRKEEKE 747 S P QGD E +E+T + + E + Sbjct: 187 SRPSQAAGDNQGD---EAKEQTFSGGTSQDTKASESSK 221 >gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] Length = 2752 Score = 109 bits (273), Expect = 8e-24 Identities = 185/681 (27%), Positives = 269/681 (39%), Gaps = 131/681 (19%) Query: 2 GRSNSRSHSSRSKSRSQSSSR-SRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSR----D 56 GRS+SRS ++R +SRS++ +R RSRS + +R RSRSRT +R RSR R +R Sbjct: 560 GRSHSRSPATRGRSRSRTPARRGRSRSRTPARR---RSRSRTPTRRRSRSRTPARRGRSR 616 Query: 57 YRRDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSP-RRGRSRSRSP 115 R R R P R R R + G R R R SR+P RRGRSRSR+P Sbjct: 617 SRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARR--GRSRSRTPARRGRSRSRTP 674 Query: 116 KRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQE 175 RRS S RSR+ +RR SR+PR SRS S RRG +T + G Sbjct: 675 ARRSGRS-RSRTPARRGRSRSRTPRRGRSRSRS-------LVRRGRSHSRTPQRRGRSGS 726 Query: 176 ESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSP--------- 226 S K+KS+ + S S E KS +S S +SPRS Sbjct: 727 SSERKNKSRTSQR----RSRSNSSPEMKKSRISS-----RRSRSLSSPRSKAKSRLSLRR 777 Query: 227 ----HSPSP---IATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGN 279 SP P TPP +S S S P + TP + S S P + S + Sbjct: 778 SLSGSSPCPKQKSQTPPRRSRSGSSQP-----KAKSRTPPRRSRSSSSPPPKQKSKT--- 829 Query: 280 GSSRYSPSQNSPIHHIPSRRSP--AKTIAPQNAPRDESRGRSSFYPDGGDQE-----TAK 332 SR S S +SP + S P +PQ + + R S + D E ++ Sbjct: 830 -PSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSR 888 Query: 333 TGKFLKSPPLHKNLDAREKSTFREESPL-RIKMIASDSHRPEVKLKMAPVPLDDSNR--- 388 SPP K+ +S R SP ++K I S R +P P ++R Sbjct: 889 HSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSH-SGSSSPSPSRVTSRTTP 947 Query: 389 -------PASLTKDRLL-------ASTLVHSVKKEQEFR-----SIFDHIKL-------- 421 P S + RLL +S+ VK E R SI + K+ Sbjct: 948 RRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGP 1007 Query: 422 -------PQASKSTSESFIQHI---VSLVHHVK------EQYFKSAAMTLNERFTSYQKA 465 P + + +S +Q +SL VK E YF +++ L + Sbjct: 1008 SLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLK----GQSQT 1063 Query: 466 TEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDID 525 + +H + SPE+ + SPS + ++Q K R S+ ++ Sbjct: 1064 SPDHRSDTSSPEVRQSHSESPS--------------LQSKSQTSPKGGRSRSSSPVTELA 1109 Query: 526 RRRKERSKERGDSKGS--RESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSA 583 R R ++RG+ S +S S +Q + D Y + DS Q ++ S Sbjct: 1110 SRSPIR-QDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTV--DSNSLLGQSRLETAESKE 1166 Query: 584 SPSSPSSREEKESKKEREEEF 604 + P + S ++++F Sbjct: 1167 KMALPPQEDATASPPRQKDKF 1187 Score = 97.1 bits (240), Expect = 5e-20 Identities = 119/393 (30%), Positives = 159/393 (40%), Gaps = 49/393 (12%) Query: 2 GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSS---RSRSRT-----YSRSRSRDRMY 53 GRS SR+ + R SRS+S RSRS R R S R RSR+ +SRSR+ R Sbjct: 493 GRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQR-- 550 Query: 54 SRDYRRDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSR 113 R R R R R RGR R GR P R SR+P R RSRSR Sbjct: 551 -RGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSR--SRTPARRRSRSRTPTRRRSRSR 607 Query: 114 SPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSP-----YSKSPVSKRRGSQEKQTKK 168 +P RR S RSR+ +RR R +RSP SRS SP S+S RRG +T Sbjct: 608 TPARRGRS--RSRTPARRRSR-TRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPA 664 Query: 169 AEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHS 228 G + +P + + + S S S + + G S HS Sbjct: 665 RRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRS---------HS 715 Query: 229 PSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQ 288 +P S SSS K+ SQ SPE S SSR S S Sbjct: 716 RTPQRRGRSGSSS---------ERKNKSRTSQRRSRSNSSPEMKKS----RISSRRSRSL 762 Query: 289 NSPIHHIPSRRSPAKTIAPQN-APRDESRGRSSFYPDGGDQETAKTGKFLKSPPLHKNLD 347 +SP SR S ++++ + P+ +S+ G Q AK+ ++PP Sbjct: 763 SSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKS----RTPPRRSRSS 818 Query: 348 AREKSTFREESPLRIKMIASDSHRPEVKLKMAP 380 + + ++P R +S H P+VK P Sbjct: 819 SSPPPKQKSKTPSRQSHSSSSPH-PKVKSGTPP 850 Score = 75.1 bits (183), Expect = 2e-13 Identities = 145/676 (21%), Positives = 246/676 (36%), Gaps = 71/676 (10%) Query: 16 RSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNNRGMRRPYGYRG 75 R SSSRS + +KK+ R R R+ S S R+R S ++ + +R Sbjct: 175 RESSSSRSPTPKQKKKKKKKDRGR-RSESSSPRRERKKSSKKKKHRSESESKKRK----- 228 Query: 76 RGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRS 135 HR ++R S+ +R RSRS +P +SRR++RS Sbjct: 229 -------------HRSPTPK--SKRKSKDKKRKRSRSTTP----------APKSRRAHRS 263 Query: 136 SRSPRSSSSRSSSPYSKSPVSKR-------RGSQEKQTKKAEGE-PQEESPLKSKSQEEP 187 + + +SSS +S S+S +K R ++ EG+ P E S + Sbjct: 264 TSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSS 323 Query: 188 KDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATP-PSQSSSCSDAP 246 +T PS ++ +K P S + S P P+P TP ++ S P Sbjct: 324 PETATKQPSSPYEDKDKDKKEKSATRPSPSP-ERSSTGPEPPAP--TPLLAERHGGSPQP 380 Query: 247 MLSTVHSAK--NTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKT 304 + +T S + N PS+ S + SP +S + SS SP P SR + + Sbjct: 381 LATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTK--VSRHASSSP 438 Query: 305 IAPQNAPRDESRGRSSFYPDGGDQE--TAKTGKFLKSPPLHKNLDAREKSTF---REESP 359 +P+ AP S S P ++ AK K P + +R +T R S Sbjct: 439 ESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSR 498 Query: 360 LRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDR------LLASTLVHSVKKEQEFR 413 K S S P+ + + S P + R S + + R Sbjct: 499 TPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSAR 558 Query: 414 SIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQ 473 H + P A++ S S +S + T R + + +R Sbjct: 559 RGRSHSRSP-ATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRS 617 Query: 474 KSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSK 533 ++P R SP R +R + R + ++ ++ R S R + ++ Sbjct: 618 RTPARRRSRTRSPVRRRSRSR-SPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPAR 676 Query: 534 ERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREE 593 G S+ + R + +TP+ + + S +R + HSR+ S S R+ Sbjct: 677 RSGRSRSRTPARRGRSRSRTPRRGRS----RSRSLVRRGRSHSRTPQRRGRSGSSSERKN 732 Query: 594 KESKKEREEEFKTHHEMKE----YSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNS 649 K +R + EMK+ +S PR + + R R +G++ P Sbjct: 733 KSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRS---KAKSRLSLRRSLSGSSPCPKQK 789 Query: 650 NTTFQKRPKEEEWDPE 665 + T +R + P+ Sbjct: 790 SQTPPRRSRSGSSQPK 805 Score = 71.6 bits (174), Expect = 2e-12 Identities = 116/456 (25%), Positives = 164/456 (35%), Gaps = 69/456 (15%) Query: 2 GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSR------ 55 GRS S +SRS+S + R + SS+S SR RSRSR R+ R Sbjct: 1760 GRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSG 1819 Query: 56 ----------DYRRDYRNNRG-MRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRR-HSR 103 R R RG R P R R R + R P +RR SR Sbjct: 1820 YHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSR 1879 Query: 104 SPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQE 163 +P R RSRS + VS +RSRSR+ + R SRS S SR S PV++RR Sbjct: 1880 TPLISRRRSRS-RTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSR 1938 Query: 164 KQT--KKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDN 221 T +++ + +S+S+ P S +S + + + S Sbjct: 1939 TPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRT 1998 Query: 222 SP----RSPHSPSPIA-------TPPS-QSSSCSDAPMLSTVHSAKNTP----------- 258 SP RS SP+ TPP+ + S S P+L S +P Sbjct: 1999 SPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRT 2058 Query: 259 ---SQHSHSIQHSP----ERSGSGSVGNGSSRYSP--------SQNSPIHHIPSRRSPAK 303 ++ S+ SP RS SGS + S +P S+ P+ SR S Sbjct: 2059 PRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFS 2118 Query: 304 TIAPQNAPRDESRGRSSFYPDGGDQETAKT-----GKFLKSP----PLHKNLDAREKSTF 354 + P D R P G + G + P P H+ E Sbjct: 2119 RPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHA- 2177 Query: 355 REESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPA 390 + L + I+ + RP + A + S PA Sbjct: 2178 QSRIALALTAISLGTARPPPSMSAAGLAARMSQVPA 2213 Score = 69.3 bits (168), Expect = 1e-11 Identities = 112/416 (26%), Positives = 155/416 (37%), Gaps = 57/416 (13%) Query: 3 RSNSRSHSSRSKS-RSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDY 61 R+ + S RS S + + RSRSRS K R + R S+S SR R SR R Sbjct: 1752 RTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVT 1811 Query: 62 RNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVS 121 R RG G GY+ R R SR+P R RSRS R+ Sbjct: 1812 RRRRG----------GSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRS---RTSP 1858 Query: 122 SQRSRSRSRRS---YRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESP 178 + RSRSR S +R SRS SR S SPVS+RR + + Sbjct: 1859 APWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPV 1918 Query: 179 LKSKSQEE-PKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSP----RSPHSPSPIA 233 + +S+ P T S + +S + + + S P RS SPI Sbjct: 1919 SRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPIT 1978 Query: 234 TPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIH 293 S+S + +P+ ++ +P S RS + V + R S S+ P Sbjct: 1979 RRRSRSRT---SPVTRRRSRSRTSPVTRRRS------RSRTSPV---TRRRSRSRTPPAI 2026 Query: 294 HIPSRRSPAKTIAPQNAPRDESRGRSSF-YPDGGDQETAKTGK----FLKSPPLHKNLDA 348 RRS ++T PR SR RS T +T + +SPP + A Sbjct: 2027 R---RRSRSRT---PLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSA 2080 Query: 349 REKSTFREESPL----------RIKMIASDSHRPEV--KLKMAPVPLDDSNRPASL 392 S+ R S R +A +S R + M+P PLD P L Sbjct: 2081 SGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGML 2136 Score = 58.9 bits (141), Expect = 2e-08 Identities = 135/608 (22%), Positives = 207/608 (34%), Gaps = 94/608 (15%) Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYS-SRSRSRTYSRSRSRDRMYSRDYRRDY 61 RS+ S S S + + S ++S S + R+ SR S S S M R Sbjct: 1377 RSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPS 1436 Query: 62 RNNRGMRRPYGYRGRGRGYYQGGG--GRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRS 119 R +R G G G G R+ G P + R+P RGRS S Sbjct: 1437 RRSRS--------GSSPGLRDGSGTPSRHSLSGSSPGM-KDIPRTPSRGRSECDSSPEPK 1487 Query: 120 VSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPL 179 Q R RS RS SS + +P +R GS+ +K +PL Sbjct: 1488 ALPQTPRPRS----------RSPSSPELNNKCLTPQRERSGSESSVDQKTVA----RTPL 1533 Query: 180 KSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQS 239 +S+ + PS S E ++S + SP S + TP Q Sbjct: 1534 GQRSRSGSSQELDVKPSASPQERSESDS-----------------SPDSKAKTRTPLRQR 1576 Query: 240 SSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRR 299 S +P + + ++ +P + RSGS R +P S P + Sbjct: 1577 SRSGSSPEVDS--KSRLSPRR---------SRSGSSPEVKDKPRAAPRAQSGSDSSPEPK 1625 Query: 300 SPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKSPPLHKNLDAREKSTFREESP 359 +P AP+ PR G SS + ++ T + PP K+ AR S Sbjct: 1626 AP----APRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPP--KSRTARRGS------- 1672 Query: 360 LRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHI 419 S P+ K + P + P K RL + S E R+ H Sbjct: 1673 -------RSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHR 1725 Query: 420 KLPQ------ASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLN--ERFTSYQKATEEHST 471 + P A KS S + S + +S + +R S + + +T Sbjct: 1726 RSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTT 1785 Query: 472 RQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKER 531 R++ R S ST R+ R RV + R + + R Sbjct: 1786 RRRD-----RSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQ-----ESSRTSS 1835 Query: 532 SKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSR--SSSSSASPSSPS 589 + RG S+ S + +P +K +S + H+R + + S S S +SP Sbjct: 1836 RRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPV 1895 Query: 590 SREEKESK 597 SR S+ Sbjct: 1896 SRRRSRSR 1903 Score = 56.2 bits (134), Expect = 1e-07 Identities = 124/620 (20%), Positives = 212/620 (34%), Gaps = 80/620 (12%) Query: 95 PVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSP 154 P ++ + R RS S SP+R +R +S ++ +RS + RS +P SK Sbjct: 185 PKQKKKKKKKDRGRRSESSSPRR-----ERKKSSKKKKHRSESESKKRKHRSPTPKSKR- 238 Query: 155 VSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWP 214 K + + K+++ P+ +S S + + D S S + ++ T Sbjct: 239 --KSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSS---DTSRSRSR-SAAAKTHTTALA 292 Query: 215 GLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGS 274 G S S R +P + P + S+ +P +T K S + + E+S Sbjct: 293 GRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETAT----KQPSSPYEDKDKDKKEKS-- 346 Query: 275 GSVGNGSSRYSPS-QNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKT 333 ++R SPS + S P +P +P+ + S P E + T Sbjct: 347 ------ATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPT 400 Query: 334 GKFLKSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLT 393 +SPP K+ + +S+ E SP + H P P S+R S + Sbjct: 401 RD--RSPP--KSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSS 456 Query: 394 KDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAM 453 SK+ S + S H + +S + Sbjct: 457 P-----------------------------TSKNRSHGRAKRDKSHSHTPSRRMGRSRSP 487 Query: 454 TLNERFTSYQKA-TEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKK 512 +R S + T+ +R +SP+ R + + G R + G + Sbjct: 488 ATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSR---SPQRPGWSR 544 Query: 513 LRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKRE 572 R + RR + RS RG S ++ R + +TP +S + R Sbjct: 545 SR--------NTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRS 596 Query: 573 QDHSRSSSSSASPSSPS-SREEKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFFRIRG 631 + +R S S +P+ SR +++ + S R R RG Sbjct: 597 RTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRG 656 Query: 632 RGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYTPKSKKYFLHDDRDDGVDYWAKRGR 691 R R+R G + S T ++ + P +S+ R +RGR Sbjct: 657 RSRSR---TPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSL-VRRGR 712 Query: 692 GRGTFQRGRGRFNFKKSGSS 711 + RGR SGSS Sbjct: 713 SHSRTPQRRGR-----SGSS 727 Score = 55.5 bits (132), Expect = 2e-07 Identities = 58/210 (27%), Positives = 78/210 (37%), Gaps = 18/210 (8%) Query: 111 RSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKA- 169 RS S S SS S S S S SS S S S SS P KR S K+A Sbjct: 2531 RSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAV 2590 Query: 170 -EGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHS 228 EG P E +P K K + + S S + SS++S S+ +S S S Sbjct: 2591 REGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPS 2650 Query: 229 P------------SPIATPPSQSSSCSDAPMLSTVHSAKNTP----SQHSHSIQHSPERS 272 P SP PP + S S + ++ +++ + S Q SP Sbjct: 2651 PAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQ 2710 Query: 273 GSGSVGNGSSRYSPSQNSPIHHIPSRRSPA 302 S S GS R + H R +P+ Sbjct: 2711 QSSSSERGSRRGQRGDSRSPSHKRRRETPS 2740 Score = 52.4 bits (124), Expect = 2e-06 Identities = 97/340 (28%), Positives = 131/340 (38%), Gaps = 51/340 (15%) Query: 3 RSNSRSHSS-RSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDY 61 RS S S S R S SSS S H K R ++R SR+ +++ R R RR Sbjct: 1635 RSRSGSSSKGRGPSPEGSSSTESSPEHPPKSR-TARRGSRSSPEPKTKSRTPPR--RRSS 1691 Query: 62 RNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRR-SV 120 R++ + R R R R P R S S +SRS +RR S Sbjct: 1692 RSSPELTRKARLSRRSRS---ASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSA 1748 Query: 121 SSQRSRSRSRRSYRSSRSPRS-SSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPL 179 SS R+++ SRR S PR SRS S K+ ++RR G Q S Sbjct: 1749 SSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRR--------DRSGSSQSTSRR 1800 Query: 180 KSKSQEEPKDTFE-------HDPSESIDEFNKSSATSGDIWPGLS----AYDNSPRSPHS 228 + +S+ + T H S + E SS TS G S RS S Sbjct: 1801 RQRSRSRSRVTRRRRGGSGYHSRSPARQE---SSRTSSRRRRGRSRTPPTSRKRSRSRTS 1857 Query: 229 PSP------IATPPSQSSSCSDAPMLSTVHSAKNTP------SQHSHSIQHSPERSGSGS 276 P+P A+P + S S P++S S T S+ S+ RS + Sbjct: 1858 PAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASP 1917 Query: 277 VGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESR 316 V S R S S+ P + RRS ++T P R SR Sbjct: 1918 V---SRRRSRSRTPP---VTRRRSRSRT--PTTRRRSRSR 1949 Score = 50.4 bits (119), Expect = 6e-06 Identities = 132/621 (21%), Positives = 209/621 (33%), Gaps = 80/621 (12%) Query: 109 RSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPY----SKSPVSKRRGSQEK 164 RS + SP+ R S+ +S+ S SP+ SRSSSP S+SP+ + RG Sbjct: 1068 RSDTSSPEVRQSHSESPSLQSK----SQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSA 1123 Query: 165 QTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGD---IWPGLSAYDN 221 G E+S +S S P D + + + +A S + + P A + Sbjct: 1124 SPMLKSGMSPEQSRFQSDSSSYP----TVDSNSLLGQSRLETAESKEKMALPPQEDATAS 1179 Query: 222 SPRSPHSPSP----------------IATPPSQSSSCSDAPMLSTVHSAKNTPSQHSH-- 263 PR SP + TPP + S +P +SA T SQ Sbjct: 1180 PPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELM 1239 Query: 264 SIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPS-RRSPAKTIA---PQNAPRDESRGRS 319 + E + + SS S P PA ++ Q+ E+ Sbjct: 1240 EVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVP 1299 Query: 320 SFYPDGGDQETAKTGKFLKSPPLHKNLDAREKSTFREESPLRIKM-------IASDSHRP 372 S G + K L + PL +N FR PL +M + D + P Sbjct: 1300 SMASSWGGPHFSPEHKELSNSPLREN-SFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGP 1358 Query: 373 EVKLKMAPVPLD---DSNRPASLTKDRLLASTLVHS-VKKEQEFRS-IFDHI-KLPQASK 426 + LD S R + + L + + + Q S + D + + P + Sbjct: 1359 FLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRER 1418 Query: 427 STSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISP 486 S+S S + L + ++ L + HS SP + + I +P Sbjct: 1419 SSSASSPEMKDGLPRTPSRRSRSGSSPGLRDG----SGTPSRHSLSGSSPGM-KDIPRTP 1473 Query: 487 STLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSK------- 539 S R + E + + + + + + +R + S+ D K Sbjct: 1474 SRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPL 1533 Query: 540 GSRESSGSR-----KQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSR--- 591 G R SGS K +P++ E S D R RS S S+ SR Sbjct: 1534 GQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSP 1593 Query: 592 EEKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFFR-IRGRGRARGVFAGTNTGPNNSN 650 S E + K + SG P+ R + R R+ G P S+ Sbjct: 1594 RRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSS 1653 Query: 651 TTFQKRPKEEEWDPEYTPKSK 671 +T E PE+ PKS+ Sbjct: 1654 ST--------ESSPEHPPKSR 1666 Score = 48.9 bits (115), Expect = 2e-05 Identities = 62/231 (26%), Positives = 92/231 (39%), Gaps = 23/231 (9%) Query: 95 PVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSP 154 P + + SPR S R+ R+RSR + R +S R+ SP Sbjct: 2373 PALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSP----- 2427 Query: 155 VSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPK----DTFEHDPSESIDEFNKSSATS- 209 S R G Q+ + Q SP+ S ++ + T S+S+ ++ TS Sbjct: 2428 -SSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSS 2486 Query: 210 -GDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHS 268 GD LS +P PH S + PP+ S+ L+ + AK S S S S Sbjct: 2487 AGDHNGMLSV--PAPGVPH--SDVGEPPA-STGAQQPSALAALQPAKERRSSSSSSSSSS 2541 Query: 269 PERSGSGSVGNGSSRYSPSQNSPIHHIP------SRRSPAKTIAPQNAPRD 313 S S S + SS S S +S +P +R P+ T AP+ A R+ Sbjct: 2542 SSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVRE 2592 Score = 48.9 bits (115), Expect = 2e-05 Identities = 57/214 (26%), Positives = 82/214 (38%), Gaps = 16/214 (7%) Query: 115 PKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEP- 173 P + + Q S + + + RS SSSS SSS S S S S + +EG Sbjct: 2509 PPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSL 2568 Query: 174 --QEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSP 231 Q E LK P P E++ E T S+ +S S S S Sbjct: 2569 PVQPEVALKRVPSPTPA------PKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSS 2622 Query: 232 IATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSP 291 ++ S SSS S + S+ S+ ++PS Q P+ + G R S S P Sbjct: 2623 SSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERR-SRSPRKP 2681 Query: 292 IHHIPSRRS------PAKTIAPQNAPRDESRGRS 319 I + RS + +PQ +PRD+ S Sbjct: 2682 IDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSS 2715 Score = 48.9 bits (115), Expect = 2e-05 Identities = 50/166 (30%), Positives = 61/166 (36%), Gaps = 23/166 (13%) Query: 104 SPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQE 163 +P + + RS S S SS S S S S SS S SSSS SSS S SP + G Q Sbjct: 2599 TPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQ- 2657 Query: 164 KQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSP 223 P+ SP K P + P + ID S + S SP Sbjct: 2658 -------ALPKPASPKK----PPPGERRSRSPRKPIDSLRDSRSLS-----------YSP 2695 Query: 224 RSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSP 269 PSP +P Q SS S+ +PS SP Sbjct: 2696 VERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSP 2741 Score = 47.4 bits (111), Expect = 5e-05 Identities = 116/558 (20%), Positives = 187/558 (33%), Gaps = 94/558 (16%) Query: 116 KRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQE 175 +R +VS +S+S+ S + P +SS +S E + Sbjct: 1276 ERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSP-----------------EHKELS 1318 Query: 176 ESPLKSKSQEEPKDTFEHDP----------SESIDEFNKSSATSGDIWPGLSAYDNSPRS 225 SPL+ S P + P SE ++ N + P L + S RS Sbjct: 1319 NSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRS 1378 Query: 226 P-HSPSPIATPPSQSSSCSDAPMLST--VHSAKNTPSQHSHSIQHSPE-----------R 271 HS S ++ + + S +S+ + + TPS+ S SPE R Sbjct: 1379 SGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRR 1438 Query: 272 SGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETA 331 S SGS S +P H S SP P+ R S SS P Q Sbjct: 1439 SRSGS----SPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPR 1494 Query: 332 KTGKFLKSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPAS 391 + SP L+ ++ ES + K +A P + + + +P++ Sbjct: 1495 PRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVA---RTPLGQRSRSGSSQELDVKPSA 1551 Query: 392 LTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSA 451 ++R + + S K + L Q S+S S + + Sbjct: 1552 SPQERSESDSSPDSKAKTRT--------PLRQRSRSGSSPEVD----------------S 1587 Query: 452 AMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDK 511 L+ R + + E + +P D SP A R ++ G Sbjct: 1588 KSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPK------APAPRALPRRSRSGSS 1641 Query: 512 -KLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHK 570 K R S + + + K R +GSR S + + +TP + +S + ++ Sbjct: 1642 SKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKA 1701 Query: 571 REQDHSRSSSS--------------SASPSSPSSREEKESKKEREEEFKTHHEMKEYSGF 616 R SRS+SS S S SSP E+ S + R + G Sbjct: 1702 RLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGR 1761 Query: 617 AGVSRPRGTFFRIRGRGR 634 + +PRG R R R R Sbjct: 1762 SPSPKPRG-LQRSRSRSR 1778 Score = 46.6 bits (109), Expect = 8e-05 Identities = 53/190 (27%), Positives = 67/190 (35%), Gaps = 39/190 (20%) Query: 134 RSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEH 193 RSS S SSSS SSS S S S GS ++ + Q E LK P Sbjct: 2531 RSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPA----- 2585 Query: 194 DPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHS 253 P E++ E P P+P SSS S Sbjct: 2586 -PKEAVREGR----------------------PPEPTPAKRKRRSSSSSSS--------- 2613 Query: 254 AKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRD 313 ++ S S S S S S S + SS S S +SP P ++ K +P+ P Sbjct: 2614 --SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPG 2671 Query: 314 ESRGRSSFYP 323 E R RS P Sbjct: 2672 ERRSRSPRKP 2681 Score = 45.8 bits (107), Expect = 1e-04 Identities = 51/156 (32%), Positives = 62/156 (39%), Gaps = 22/156 (14%) Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDY- 61 R +S S SS S S S SSS S S S S SS S S + S S S + + + Sbjct: 2605 RRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPAS 2664 Query: 62 --------RNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSR 113 R +R R+P R Y PV RR S P +S Sbjct: 2665 PKKPPPGERRSRSPRKPIDSLRDSRSL-----------SYSPVERRRPSPQPSPRDQQSS 2713 Query: 114 SPKRRSVSSQR--SRSRSRRSYRSSRSPRSSSSRSS 147 S +R S QR SRS S + R + SPR RSS Sbjct: 2714 SSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSS 2749 Score = 30.0 bits (66), Expect = 8.2 Identities = 19/49 (38%), Positives = 20/49 (40%) Query: 548 RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKES 596 R E TP K S S S SSSSS+S SS SS S Sbjct: 2594 RPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2642 >gi|115511057 hypothetical protein LOC256643 [Homo sapiens] Length = 682 Score = 103 bits (258), Expect = 4e-22 Identities = 154/644 (23%), Positives = 255/644 (39%), Gaps = 109/644 (16%) Query: 4 SNSRSHSSRSKSRSQSSSRSRSRSHSRKK--------------------RYSSRSRSRTY 43 + SRS S R K RS S R+ H +++ R S ++ Sbjct: 2 ARSRSRSPRWKHRSLSPV-PRNAEHYKQRHSHGHYGCEYRKDPKRPVAWRMDSEKHGQSK 60 Query: 44 SRSRSRDRMYSRDYRR-----DYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWN 98 R SR +Y + Y + RN+ + Y Y+ RGY G G R Y P ++ Sbjct: 61 PRIPSRGNIYYQSYEHRSPSPNIRNS--LENVYMYKPH-RGYSPGRGDSNRRAQYMPKYS 117 Query: 99 RRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSS---------- 148 P + R+ P++ R R S + + P+ S + S Sbjct: 118 EG---IPYKEHERNSYPQKVQGGHSPDDHRVRGSGKGGKPPQRSIADSFRFEGKWHEDEL 174 Query: 149 -----PYSKSPVSKRRGSQEKQTKKA--EGEPQEESPLK-SKSQEEPKDTFEHD------ 194 K S RRGS++ +T+ + + P++ K + + PKD ++ Sbjct: 175 RHQRIQEEKYSQSTRRGSEDFETRSSFQKRYPEDRDFRKYGHTSKRPKDVERYESREPAR 234 Query: 195 -----PSESIDEFNKSSATSGDIWP-GLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPML 248 P S+ + + + D W G Y ++ R H + AT S +L Sbjct: 235 NPKWKPEHSLPPYQEDT----DQWNLGPQTYRHAERE-HPETSSATKVSYDYRHKRPKLL 289 Query: 249 STVHSAKNTPSQ-------HSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSP 301 + +Q +S Q P G R +Q+ + P + S Sbjct: 290 DGDQDFSDGRTQKYCKEEDRKYSFQKGPLNRELDCFNTGRGR--ETQDGQVKE-PFKPSK 346 Query: 302 AKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKSPPLHKN-LDAREKSTFREESPL 360 +IA + +++ RSS D ++ K G K N LD +K + SP+ Sbjct: 347 KDSIACTYSNKNDVDLRSS--NDKWKEKIKKEGDCRKESNSSSNQLDKSQKLPDVKPSPI 404 Query: 361 RIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIK 420 ++ S +V +K +D +S + +R ++ LV +K + F +F+H+ Sbjct: 405 NLR---KKSLTVKVDVKKT---VDTFRVASSYSTERQMSHDLVAVGRKSENFHPVFEHLD 458 Query: 421 LPQ--ASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQ---KATEEHSTRQKS 475 Q +K T E F Q I++++H VK YF S +TL+ERF++ Q KA Sbjct: 459 STQNTENKPTGE-FAQEIITIIHQVKANYFPSPGITLHERFSTMQDIHKADVNEIPLNSD 517 Query: 476 PEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKER 535 PEIHRRID+S + L+ ++ V E Q K + D DLRHDI+RRRKER + Sbjct: 518 PEIHRRIDMSLAELQ------SKQAVIYESEQTLIKII--DPNDLRHDIERRRKERLQNE 569 Query: 536 GD---------SKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHK 570 + + + SS S+ KD +K ++ + H+ Sbjct: 570 DEHIFHIASAAERDDQNSSFSKNYTTQRKDIITHKPFEVEGNHR 613 >gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] Length = 715 Score = 96.3 bits (238), Expect = 9e-20 Identities = 98/347 (28%), Positives = 136/347 (39%), Gaps = 64/347 (18%) Query: 2 GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDY 61 G S+ R S RS+S S + R SRS S K RSRSR+ ++R R R S + RD Sbjct: 379 GSSSPRKESGRSQSGSPNKQRDHSRSRSPNKA-RDRSRSRSPYKARDRSRSRSPNKARDC 437 Query: 62 RNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPR--RGRSRSRSPKRRS 119 +R PY R R R + R SRSP R RSRSRSP + Sbjct: 438 SRSRS---PYKARDRSRSRSPNKARDHSR-----------SRSPNKARDRSRSRSPSKER 483 Query: 120 VSSQRSRSRSRRSYRSSRSP---------RSSSSRSSSPYSKSPVSKRRGSQEKQTKKAE 170 SQ R +R SRSP RSSS S+SP +R+ Q + K Sbjct: 484 DHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKER 543 Query: 171 GEPQEESP--------LKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNS 222 Q SP +S S+E + + E ++SS+ D + Sbjct: 544 DRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERD--------HSR 595 Query: 223 PRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSS 282 RSP+ S + P + S + +HS +P + G+ S SS Sbjct: 596 SRSPNKQSGYSRPRASS-------------------KEKAHSRSRTPSKEGNHSQSRTSS 636 Query: 283 RYSPSQNSPIHHIPS-RRSPAKT--IAPQNAPRDESRGRSSFYPDGG 326 + S S + P +RSP +T ++ P S S +P GG Sbjct: 637 KESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGG 683 Score = 84.0 bits (206), Expect = 5e-16 Identities = 154/679 (22%), Positives = 246/679 (36%), Gaps = 98/679 (14%) Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYR 62 R++ S SS ++S S+ R+ S S + R RS++RT SR + R D R Sbjct: 53 RNSVMSPSSSKSTKSTSTKRAPSNRPSSRSRV--RSKARTPSRVSTDTRTSKASKASDVR 110 Query: 63 NNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSS 122 ++ RR RGR G RR SRS +R SR+ +P R Sbjct: 111 CHQ--RRGTHSRGRTPG-------------------RRGSRSSKRSPSRASTPGR----- 144 Query: 123 QRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSK 182 R+ + +SR +P S+ S+ + +T E + L K Sbjct: 145 ----------IRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQPRNLSKK 194 Query: 183 SQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIAT-----PPS 237 S P + SE + + + P DN SP S + + PS Sbjct: 195 SYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNP--SPSSSRKVKSYGQMIIPS 252 Query: 238 QSSSCSDAPMLSTVHS---AKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHH 294 + S S M S V S A SHS SP RS SGS SR S + +H Sbjct: 253 REKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVR-SHSWKRNH 311 Query: 295 IPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKSPPLHKNLDAREKSTF 354 +R K I Q +SR S G Q ++T + +S +N + Sbjct: 312 SRARSRTRKGILSQMGRHSQSRSHSK----GKSQNQSRTPRRGRSHNWSRNPSKERSHSH 367 Query: 355 REESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRS 414 S S S R E + P + S + ++ + S K ++ Sbjct: 368 SRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSR 427 Query: 415 IFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQK 474 K S+S S +K+ R S KA + +R Sbjct: 428 SRSPNKARDCSRSRSP-----------------YKARD---RSRSRSPNKARDHSRSRSP 467 Query: 475 SPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLR-CDSADLRHDIDRRRKERSK 533 + R SPS R H++L + + K R C R+ + SK Sbjct: 468 NKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQC----------RQSRSSSK 517 Query: 534 ERGDSKGSRESS--GSRKQEKTP---KDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSP 588 ER D + SR S R+Q ++P +D + +S ++ +H++ + S+ S Sbjct: 518 ER-DHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPS 576 Query: 589 SSREEKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFFRIRGRGRAR-----GVFAGTN 643 RE ++S+ EE + H + + +G SRPR + + + R+R G + + Sbjct: 577 KERERRQSRSSSEE--RDHSRSRSPNKQSGYSRPRAS-SKEKAHSRSRTPSKEGNHSQSR 633 Query: 644 TGPNNSNTTFQKRPKEEEW 662 T S+ + P+ +W Sbjct: 634 TSSKESDPSQSTVPRSPDW 652 Score = 79.0 bits (193), Expect = 2e-14 Identities = 162/620 (26%), Positives = 233/620 (37%), Gaps = 72/620 (11%) Query: 2 GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDY 61 GR SRS S RS SR+ S+ R R+H + +SR R+ T + SR + Y R R Sbjct: 125 GRRGSRS-SKRSPSRA--STPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRP--RTS 179 Query: 62 RNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSP-KRRSV 120 R +P + Y GG R V + S + ++ + P K +S Sbjct: 180 NRERSDSQPRNL--SKKSYRPPGGSGIGRSSELAV-----TPSTAKCQTPTGIPSKEKSD 232 Query: 121 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGS--QEKQTKKAEGEPQEESP 178 + S SR +SY P S YS + +S R S Q + + Q SP Sbjct: 233 NPSPSSSRKVKSYGQMIIPSREKS-----YSPTEMSSRVKSYNQASTRSRPQSHSQSRSP 287 Query: 179 LKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRS-PHSPSPIATPPS 237 +S+S + K T S S N S A S LS +S HS Sbjct: 288 RRSRSGSQ-KRTHSRVRSHSWKR-NHSRARSRTRKGILSQMGRHSQSRSHS-------KG 338 Query: 238 QSSSCSDAPMLSTVHSAKNTPSQ---HSHSIQHSPERS--GSGSVGNGSSR-YSPSQNSP 291 +S + S P H+ PS+ HSHS S ER GS S S R S S N Sbjct: 339 KSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQ 398 Query: 292 IHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKSPPLHKNLDAREK 351 H S RSP N RD SR RS + A+ +SP ++ +R + Sbjct: 399 RDHSRS-RSP-------NKARDRSRSRSPY--------KARDRSRSRSPNKARDC-SRSR 441 Query: 352 STF--REESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKE 409 S + R+ S R A D R +P D +R S +K+R + + S KE Sbjct: 442 SPYKARDRSRSRSPNKARDHSR-----SRSPNKARDRSRSRSPSKER--DHSQLGSPSKE 494 Query: 410 QEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKA---- 465 ++ R K Q +S S S + KE+ + + ER S ++ Sbjct: 495 RDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEE 554 Query: 466 TEEHSTRQKSPEIHRRIDISPS--TLRKHTRLAGEERVFKE----ENQKGDKKLRCDSAD 519 E +R S E RR SPS R+ +R + EER Q G + R S + Sbjct: 555 REHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKE 614 Query: 520 LRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSS 579 H R + S+ES S+ D+K + R + S Sbjct: 615 KAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSH 674 Query: 580 SSSASPSSPSSREEKESKKE 599 S S PS + + +S+ + Sbjct: 675 SPSTFPSGGQTLSQDDSQAD 694 Score = 52.4 bits (124), Expect = 2e-06 Identities = 107/504 (21%), Positives = 180/504 (35%), Gaps = 84/504 (16%) Query: 141 SSSSRSSSP-YSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESI 199 SS RSS P S +P + + + + + +P +S +P + S S Sbjct: 2 SSPKRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPSS 61 Query: 200 DEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPS 259 + KS++T A N P S A PS+ S+ + S + Sbjct: 62 SKSTKSTSTK-------RAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQR 114 Query: 260 QHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESR-GR 318 + +HS +P R GS S S+RSP++ P +R G Sbjct: 115 RGTHSRGRTPGRRGSRS--------------------SKRSPSRASTPGRIRTHGARPGM 154 Query: 319 SSFYPDGGDQETAKTGKFLKSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKM 378 +S Q+ GK P +++ RE S + + ++ S+RP Sbjct: 155 ASRVRTPTSQQKGSRGKSYGRP----------RTSNRERSDSQPRNLSKKSYRP------ 198 Query: 379 APVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVS 438 P R + S K Q I K S S+S + Sbjct: 199 ----------PGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQM 248 Query: 439 LVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGE 498 ++ ++ Y + ++ R SY +A+ + S R S S R H+R+ Sbjct: 249 IIPSREKSY---SPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSH 305 Query: 499 ERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYK 558 +K + + + R I + S+ R SKG S+ Q +TP+ + Sbjct: 306 S--WKRNHSRARSRTR-------KGILSQMGRHSQSRSHSKGK-----SQNQSRTPRRGR 351 Query: 559 EYKSYKDDSKHKREQDHSRSSS------SSASPSSPSSREEKESKKEREEEFKTHHEMKE 612 + ++ SK +R HSRSSS S+SP S R + S ++ + H + Sbjct: 352 SHNWSRNPSK-ERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRD----HSRSRS 406 Query: 613 YSGFAGVSRPRGTFFRIRGRGRAR 636 + SR R ++ R R R+R Sbjct: 407 PNKARDRSRSRSP-YKARDRSRSR 429 Score = 50.8 bits (120), Expect = 4e-06 Identities = 113/536 (21%), Positives = 187/536 (34%), Gaps = 47/536 (8%) Query: 110 SRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKA 169 ++S +P R V ++ + SR+ S SP SS S S+ ++P S R S+ + KA Sbjct: 35 TKSATPNRSLVPTKPATSRN-----SVMSPSSSKSTKSTSTKRAP-SNRPSSRSRVRSKA 88 Query: 170 EGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSP 229 + + ++ + D H + S PG +S RSP Sbjct: 89 RTPSRVSTDTRTSKASKASDVRCHQ---------RRGTHSRGRTPGRRGSRSSKRSPSRA 139 Query: 230 SPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSR--YSPS 287 S + + A + T S + S+ + R S S S+ Y P Sbjct: 140 STPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRPP 199 Query: 288 QNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKSPPLHKNLD 347 S I RS + P A G S + D + + + +KS + Sbjct: 200 GGSGIG-----RSSELAVTPSTAKCQTPTGIPS--KEKSDNPSPSSSRKVKSYG-QMIIP 251 Query: 348 AREKSTFREESPLRIKMI--ASDSHRPEVKLKM-APVPLDDSNRPASLTKDRLLASTLVH 404 +REKS E R+K AS RP+ + +P ++ + ++ R + H Sbjct: 252 SREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNH 311 Query: 405 SVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQK 464 S + + + I + S+S S+ Q+ + + S Sbjct: 312 SRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSS 371 Query: 465 ATEEHSTRQKSP--EIHRRIDISPSTLRKHTRLAG----EERVFKEENQKGDKKLRCDSA 518 + E SP E R SP+ R H+R +R K + R S Sbjct: 372 SKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSP 431 Query: 519 DLRHDIDRRR-----KERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHK--- 570 + D R R ++RS+ R +K +R+ S SR K +D +S + H Sbjct: 432 NKARDCSRSRSPYKARDRSRSRSPNK-ARDHSRSRSPNKA-RDRSRSRSPSKERDHSQLG 489 Query: 571 ---REQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKEYSGFAGVSRPR 623 +E+DH RS S S SR + + R + + S R R Sbjct: 490 SPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDR 545 >gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] Length = 494 Score = 93.6 bits (231), Expect = 6e-19 Identities = 100/288 (34%), Positives = 133/288 (46%), Gaps = 32/288 (11%) Query: 4 SNSRSHS-SRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD-- 60 S+S+S S SRS SRS+S SRSRS+S SR K+ SRS S+ SRSRS SR +D Sbjct: 214 SHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQA 273 Query: 61 ---YRNNRGMRRPYG-------------YRGRGRGYYQGGGGRYHRG-GYRPVWNRRHSR 103 +NN + +P R + R + G RG + SR Sbjct: 274 EEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSR 333 Query: 104 SPRRGRSRSRSPKR-RSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQ 162 S +G SRSRS R +S ++ R RSR RS RS S RS SK + GS Sbjct: 334 SRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKR--DSKAGSS 391 Query: 163 EKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESID-EFNKSSATSGDIWPGLS-AYD 220 +K+ K+ Q SP +S S+E EH SES E S +G S + Sbjct: 392 KKKKKEDTDRSQSRSPSRSVSKER-----EHAKSESSQREGRGESENAGTNQETRSRSRS 446 Query: 221 NSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHS 268 NS P+ PS + S+S+S + + S SA +PS+ S S HS Sbjct: 447 NSKSKPNLPSE-SRSRSKSASKTRSRSKSRSRSASRSPSR-SRSRSHS 492 Score = 67.4 bits (163), Expect = 5e-11 Identities = 74/224 (33%), Positives = 97/224 (43%), Gaps = 49/224 (21%) Query: 1 MGRSNSRS---HSSRSKSRSQSSSR----------SRSRSHSRKKRYS-SRSRSRTYSRS 46 +G+ SRS H S+SKSRS+S R SR RS + R S SRSRS+ SRS Sbjct: 283 VGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRS 342 Query: 47 RSRDRMYSRDYR------RDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRR 100 RSR R S+D R R+ +R R R R RG + + + +R Sbjct: 343 RSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRS 402 Query: 101 HSRSPRRGRSRSRSPKRRSVSSQR----------------SRSRSRRSYRSSRSPRSSSS 144 SRSP R S+ R +S SSQR SRSRS S P S S Sbjct: 403 QSRSPSRSVSKERE-HAKSESSQREGRGESENAGTNQETRSRSRS-NSKSKPNLPSESRS 460 Query: 145 RSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPK 188 RS S SK R + +++ A SP +S+S+ + Sbjct: 461 RSKS------ASKTRSRSKSRSRSA-----SRSPSRSRSRSHSR 493 Score = 59.3 bits (142), Expect = 1e-08 Identities = 66/241 (27%), Positives = 91/241 (37%), Gaps = 16/241 (6%) Query: 101 HSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRG 160 + R R + S +RRS S RS SRSR R SR RS S S S +SKS R G Sbjct: 166 NGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSG 225 Query: 161 SQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYD 220 S+ + K+ Q S K + P S S KS + S D A + Sbjct: 226 SRSR--SKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSA---GKSRSKSKD-----QAEE 275 Query: 221 NSPRSPHSPSPIATPPSQSSSCSDAPMLS---TVHSAKNTPSQHSHSIQHSPERSGSGSV 277 + + P + PS+ S S + S V K S + S +S S S Sbjct: 276 KIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSR 335 Query: 278 GNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFL 337 G SR S++ +R K ++ R SR +S G + +K G Sbjct: 336 SKGGSR---SRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSK 392 Query: 338 K 338 K Sbjct: 393 K 393 Score = 48.5 bits (114), Expect = 2e-05 Identities = 65/324 (20%), Positives = 113/324 (34%), Gaps = 46/324 (14%) Query: 456 NERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRC 515 + R SY ++ +R +S + S S+ H++ R K + + Sbjct: 179 SRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQS 238 Query: 516 DSADLRHDIDRRRKERSKERGDSKG-SRESSGSRKQEK-------------TPKDYKEYK 561 S + KE+S+ R S G SR S + +EK +P +K Sbjct: 239 RSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKS 298 Query: 562 SYKDDSKHKREQDHSRSS-------------SSSASPSSPSSREEKESKKEREEEFKTHH 608 + S+ +R ++ R S S S S S SR S+ + +++ K Sbjct: 299 KSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRK 358 Query: 609 EMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYTP 668 +E S SR R R R RG R AG++ K+ K+E+ D + Sbjct: 359 RSREES--RSRSRSRSKSERSRKRGSKRDSKAGSS-----------KKKKKEDTDRSQSR 405 Query: 669 KSKKYFLHDDRDDGVDYWAKRGRGR----GTFQ--RGRGRFNFKKSGSSPKWTHDKYQGD 722 + + + + GRG GT Q R R R N K + P + + + Sbjct: 406 SPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSA 465 Query: 723 GIVEDEEETMENNEEKKDRRKEEK 746 ++ + + R + Sbjct: 466 SKTRSRSKSRSRSASRSPSRSRSR 489 Score = 47.4 bits (111), Expect = 5e-05 Identities = 74/368 (20%), Positives = 135/368 (36%), Gaps = 38/368 (10%) Query: 265 IQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPD 324 ++H+ GS G+G S Y ++ + P R+ + I + R + + Sbjct: 67 VEHARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDLKDYMRQ 126 Query: 325 GGDQETAKTGKFLKSPPLHKNLD------AREKSTFREESPLRIKMIAS---DSHRPEVK 375 G+ A K K+ + + + A EK E + +I+++ R Sbjct: 127 AGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYS 186 Query: 376 LKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQH 435 + +R + ++ R +S HS + + K S+S S S + Sbjct: 187 RSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEK 246 Query: 436 IVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHST----RQKSPEIHRRIDISPSTLRK 491 S SA + ++ ++ + + + +SP H+ + Sbjct: 247 SRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKS--------KS 298 Query: 492 HTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRR---------KERSKERGDSKG-- 540 +R +ER +EE + + R LR R R + RSK + KG Sbjct: 299 KSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRK 358 Query: 541 -SRESSGSRKQEKTPKDYKEYKSYKDD-----SKHKREQDHSRSSSSSASPSSPSSREEK 594 SRE S SR + ++ + + K D SK K+++D RS S S S S RE Sbjct: 359 RSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHA 418 Query: 595 ESKKEREE 602 +S+ + E Sbjct: 419 KSESSQRE 426 Score = 46.6 bits (109), Expect = 8e-05 Identities = 52/231 (22%), Positives = 86/231 (37%), Gaps = 33/231 (14%) Query: 505 ENQKGDKKLRCDSADLRHDIDRRRKERSKER----GDSKGSRESSGSRKQEKTPKDYKEY 560 E++ G ++ R S H R R S++ G SK S S SR + + K Sbjct: 174 EDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSR 233 Query: 561 KSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFK-------------TH 607 + S+ K+E+ S S S S S + + +SK + EE+ + + Sbjct: 234 SRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSR 293 Query: 608 HEMKEYSGFAGVSR-----PRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEW 662 H+ K S R RG+ RGR + + + + + + + R + + Sbjct: 294 HKSKSKSRSRSQERRVEEEKRGSV--SRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSK 351 Query: 663 DPEYTPKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPK 713 D K +K + R R R + R RG K+GSS K Sbjct: 352 DKR---KGRKRSREESRS------RSRSRSKSERSRKRGSKRDSKAGSSKK 393 Score = 44.3 bits (103), Expect = 4e-04 Identities = 79/350 (22%), Positives = 133/350 (38%), Gaps = 54/350 (15%) Query: 261 HSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSS 320 +S S HS RS S SR S++S RS +++ R +SR RS Sbjct: 185 YSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRS-------RSKSRSRS- 236 Query: 321 FYPDGGDQETAKTGKFLKSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAP 380 Q +++ K P ++EKS R S + + + D +++ Sbjct: 237 -------QSRSRSKKEKSRSP------SKEKSRSRSHSAGKSRSKSKDQAEEKIQNN--- 280 Query: 381 VPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLV 440 D+ +P S + R + + S +E+ + K S+ S+ SL Sbjct: 281 ---DNVGKPKSRSPSRHKSKSKSRSRSQERRV----EEEKRGSVSRGRSQE-----KSLR 328 Query: 441 HHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEER 500 K + + R S K+ ++ R++S E R S S + +R G +R Sbjct: 329 QSRSRSRSKGGSRS---RSRSRSKSKDKRKGRKRSREESRSRSRSRSKSER-SRKRGSKR 384 Query: 501 VFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDS-----KGSRESSGSRKQEKT-- 553 K + K KK D + R KER + +S +G E++G+ ++ ++ Sbjct: 385 DSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRS 444 Query: 554 -------PKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKES 596 P E +S + R + SRS S+S SPS SR S Sbjct: 445 RSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSRS 494 Score = 43.9 bits (102), Expect = 5e-04 Identities = 30/55 (54%), Positives = 37/55 (67%), Gaps = 8/55 (14%) Query: 3 RSNSRSHS---SRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYS 54 RSNS+S S S+SRS+S+S++RSRS SR SRS SR+ SRSRSR S Sbjct: 445 RSNSKSKPNLPSESRSRSKSASKTRSRSKSR-----SRSASRSPSRSRSRSHSRS 494 >gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sapiens] Length = 805 Score = 89.0 bits (219), Expect = 1e-17 Identities = 95/284 (33%), Positives = 129/284 (45%), Gaps = 32/284 (11%) Query: 4 SNSRSHSSRSKSRSQSSSRSRSRSHS--RKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDY 61 S S + SS S S S SSR+ SRS S RKKR+S RSRS T RSR R YSR R Sbjct: 526 STSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHS-RSRSPTIKARRSRSRSYSR--RIKI 582 Query: 62 RNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSP--RRGRSRSRSPKRRS 119 +NR + R R + RR +RSP R RSRSRS RR+ Sbjct: 583 ESNRARVKIRDRRRSNRNSIER--------------ERRRNRSPSRERRRSRSRSRDRRT 628 Query: 120 VSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQ--EKQTKKAEGE-PQEE 176 + RSRSR RR R S +S +K K+ S+ +K KK + E +E+ Sbjct: 629 NRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQ 688 Query: 177 SPLKSKSQEEPKD---TFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIA 233 K K + E KD + + D + E ++ + SG I + +D+ S S + + Sbjct: 689 DKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDS 748 Query: 234 TPPSQSS----SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSG 273 S S S S++P S AK S S++ S +RSG Sbjct: 749 KKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKS-QRSG 791 Score = 52.0 bits (123), Expect = 2e-06 Identities = 45/170 (26%), Positives = 74/170 (43%), Gaps = 18/170 (10%) Query: 451 AAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAG----EERVFKEEN 506 A + + +R S + + E R +SP RR S S R+ R + + R ++ Sbjct: 587 ARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQR 646 Query: 507 ---------QKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDY 557 KG+ K + + ID+ RK++ KER + R+ KQ++ KD+ Sbjct: 647 GNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKE----KQKREEKDF 702 Query: 558 KEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH 607 K + S D K KRE + + S S S S ++SKK ++ K H Sbjct: 703 K-FSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKH 751 Score = 50.4 bits (119), Expect = 6e-06 Identities = 115/578 (19%), Positives = 209/578 (36%), Gaps = 86/578 (14%) Query: 60 DYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRS------- 112 DY++ P G G Y+Q G G P NRR S R R RS Sbjct: 165 DYQHGAAFGPPQG--GFHPPYWQPGPP----GPPAPPQNRRERPSSFRDRQRSPIALPVK 218 Query: 113 RSPKRRSVSSQRSRSRSRRS--YRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAE 170 + P + +R+ R + R + + +S +SK+ ++K T+ AE Sbjct: 219 QEPPQIDAVKRRTLPAWIREGLEKMEREKQKKLEKERMEQQRSQLSKK---EKKATEDAE 275 Query: 171 GEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPS 230 G P +SK F+ D E D N +A+SG + S P+ HS Sbjct: 276 GGDGPRLPQRSK--------FDSDEEEE-DTENVEAASSGKVTRSPSPV---PQEEHSDP 323 Query: 231 PIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNS 290 + + ML T T + + + + Sbjct: 324 EMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKDA---------------------- 361 Query: 291 PIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKSPP-----LHKN 345 H + ++PAK +A +A + GD E ++ + +S L Sbjct: 362 ---HRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHR 418 Query: 346 LDAREKSTFREESPLRI---KMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTL 402 + ++++ +R+E ++ K + + + E K + SL + R + Sbjct: 419 IRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDV 478 Query: 403 VHSVKKE-QEFRSIFD----HIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNE 457 V+ K+ E S+ + H + + +S S S S S + T++ Sbjct: 479 VNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSS-----SNSRTSSTSSTVSS 533 Query: 458 RFTSYQKATEEHSTRQKSPEIHRRIDIS--PSTLRKHTRLAGEERVFKEENQKGDKKLRC 515 S + S+R SP+ +R S P+ + +R R K E+ + K+R Sbjct: 534 SSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIR- 592 Query: 516 DSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKT-PKDYKEYKSYKDDSKHKREQD 574 DRRR R+ + + +R S R++ ++ +D + ++ + S+ +R+ D Sbjct: 593 ---------DRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKID 643 Query: 575 HSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKE 612 R + S S +E+E KKER + K+ Sbjct: 644 DQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKD 681 Score = 47.8 bits (112), Expect = 4e-05 Identities = 38/168 (22%), Positives = 74/168 (44%), Gaps = 15/168 (8%) Query: 2 GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDY 61 G + SH + +++ Q + RSRS + ++ + R R + + + + +D++ Sbjct: 647 GNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSS 706 Query: 62 RNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRR--S 119 +++R R+ R + R G V RH +S ++ K+ S Sbjct: 707 QDDRLKRKRESER------------TFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGS 754 Query: 120 VSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTK 167 SS RS S S S + ++ + SRS S KS S ++ S++ ++K Sbjct: 755 DSSGRSSSESPGSSKEKKAKKPKHSRSRS-VEKSQRSGKKASRKHKSK 801 Score = 45.8 bits (107), Expect = 1e-04 Identities = 53/226 (23%), Positives = 85/226 (37%), Gaps = 19/226 (8%) Query: 541 SRESSGSRKQEK--TPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKK 598 +RE+ G EK TP + K + K K +Q SRS SSS+ SS +SR S Sbjct: 471 AREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSST 530 Query: 599 EREEEFKTHHEMKEYSGFAGV-------SRPRGTFF---RIRGRGRARGVFAGTNTG--- 645 + + S + SR R R R R +R + +N Sbjct: 531 VSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVK 590 Query: 646 ---PNNSNTTFQKRPKEEEWDPEYTPKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGR 702 SN +R + P + + D R + R R + QRG Sbjct: 591 IRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLS 650 Query: 703 FN-FKKSGSSPKWTHDKYQGDGIVEDEEETMENNEEKKDRRKEEKE 747 N K G + + K + I +D ++ + E ++D+RKE+++ Sbjct: 651 GNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQK 696 Score = 45.8 bits (107), Expect = 1e-04 Identities = 52/209 (24%), Positives = 81/209 (38%), Gaps = 23/209 (11%) Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYR 62 R++ R++S S+ RSRSRS R R+ SRSRSRDR D R + Sbjct: 599 RNSIERERRRNRSPSRERRRSRSRSRDR--------RTNRASRSRSRDRRKIDDQRGNLS 650 Query: 63 NNRGMRRPYGYRGRGRGYYQGGGGRYHRG---GYRPVWNRRHSRSPRRGRSRSRSPKRRS 119 N ++ +G Q R + R +R + R K Sbjct: 651 GN-------SHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFK 703 Query: 120 VSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKR---RGSQEKQTKKAEGEPQEE 176 SSQ R + +R + S S S + SK+ + S++ + G E Sbjct: 704 FSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSE 763 Query: 177 SPLKSKSQEEPKDTFEHDPSESIDEFNKS 205 SP SK ++ K +H S S+++ +S Sbjct: 764 SPGSSKEKKAKKP--KHSRSRSVEKSQRS 790 Score = 45.1 bits (105), Expect = 2e-04 Identities = 39/154 (25%), Positives = 72/154 (46%), Gaps = 18/154 (11%) Query: 470 STRQKSPEIHRRIDISPSTL----RKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDID 525 ++R +S + R+ID L KH A E+ KE ++ DK + + + D Sbjct: 631 ASRSRSRD-RRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQD 689 Query: 526 RRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSY---------KDDSKHKREQD-- 574 +R++++ +E D K S + +++ ++ + + S + DSK +D Sbjct: 690 KRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSK 749 Query: 575 -HSRSSSSSASPS-SPSSREEKESKKEREEEFKT 606 HS S SS S S SP S +EK++KK + ++ Sbjct: 750 KHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRS 783 Score = 43.5 bits (101), Expect = 7e-04 Identities = 103/473 (21%), Positives = 160/473 (33%), Gaps = 63/473 (13%) Query: 133 YRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFE 192 Y S S S R S R ++KQ E +E+ L K EE K E Sbjct: 391 YGSGDSEDERSDRGSESSDTDDEELRHRIRQKQEAFWRKE-KEQQLLHDKQMEEEKQQTE 449 Query: 193 HDPSESIDEFNKSSATSGDIWPGLSA----YDNSPRSPHSPSPIATPPSQSSSCSDAPML 248 E ++EF S + A + R+P+ + + P + Sbjct: 450 RVTKE-MNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRS 508 Query: 249 STVHSAKNTPSQHSH-SIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAP 307 + S+ + S +S S S S S S +GSSR S +SP RS + TI Sbjct: 509 RSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTI-- 566 Query: 308 QNAPRDESRGRSSFYPDGGDQETAKTGKFLKSPPLHKNLDAREKSTFREESPLRIKMIAS 367 A R SR S ++ K +S N ++ E+ R SP R Sbjct: 567 -KARRSRSRSYSRRIKIESNRARVKIRDRRRS-----NRNSIERERRRNRSPSR------ 614 Query: 368 DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS 427 + R S ++DR T S + ++ R I D Q Sbjct: 615 -----------------ERRRSRSRSRDR---RTNRASRSRSRDRRKIDD-----QRGNL 649 Query: 428 TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS 487 + S + K++ +S ++ ++ ++ +QK E + Sbjct: 650 SGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDD 709 Query: 488 TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS 547 L++ ER F K +R HD + K +S + K S S Sbjct: 710 RLKRKRE---SERTFSRSGSISVKIIR-------HDSRQDSK-KSTTKDSKKHSGSDSSG 758 Query: 548 RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKER 600 R ++P KE K+ K KH R SRS S +SR+ K + R Sbjct: 759 RSSSESPGSSKEKKAKK--PKHSR----SRSVEKSQRSGKKASRKHKSKSRSR 805 Score = 34.3 bits (77), Expect = 0.43 Identities = 17/48 (35%), Positives = 28/48 (58%) Query: 2 GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSR 49 GRS+S S S + +++ SRSRS + +R ++ + S+SRSR Sbjct: 758 GRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKSRSR 805 Score = 31.6 bits (70), Expect = 2.8 Identities = 19/59 (32%), Positives = 31/59 (52%), Gaps = 1/59 (1%) Query: 5 NSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRN 63 +S+ HS S S +SSS S S +K + SRSR+ +S+ + SR ++ R+ Sbjct: 747 DSKKHSG-SDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKSRS 804 >gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sapiens] Length = 805 Score = 89.0 bits (219), Expect = 1e-17 Identities = 95/284 (33%), Positives = 129/284 (45%), Gaps = 32/284 (11%) Query: 4 SNSRSHSSRSKSRSQSSSRSRSRSHS--RKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDY 61 S S + SS S S S SSR+ SRS S RKKR+S RSRS T RSR R YSR R Sbjct: 526 STSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHS-RSRSPTIKARRSRSRSYSR--RIKI 582 Query: 62 RNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSP--RRGRSRSRSPKRRS 119 +NR + R R + RR +RSP R RSRSRS RR+ Sbjct: 583 ESNRARVKIRDRRRSNRNSIER--------------ERRRNRSPSRERRRSRSRSRDRRT 628 Query: 120 VSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQ--EKQTKKAEGE-PQEE 176 + RSRSR RR R S +S +K K+ S+ +K KK + E +E+ Sbjct: 629 NRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQ 688 Query: 177 SPLKSKSQEEPKD---TFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIA 233 K K + E KD + + D + E ++ + SG I + +D+ S S + + Sbjct: 689 DKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDS 748 Query: 234 TPPSQSS----SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSG 273 S S S S++P S AK S S++ S +RSG Sbjct: 749 KKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKS-QRSG 791 Score = 52.0 bits (123), Expect = 2e-06 Identities = 45/170 (26%), Positives = 74/170 (43%), Gaps = 18/170 (10%) Query: 451 AAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAG----EERVFKEEN 506 A + + +R S + + E R +SP RR S S R+ R + + R ++ Sbjct: 587 ARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQR 646 Query: 507 ---------QKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDY 557 KG+ K + + ID+ RK++ KER + R+ KQ++ KD+ Sbjct: 647 GNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKE----KQKREEKDF 702 Query: 558 KEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH 607 K + S D K KRE + + S S S S ++SKK ++ K H Sbjct: 703 K-FSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKH 751 Score = 50.4 bits (119), Expect = 6e-06 Identities = 115/578 (19%), Positives = 209/578 (36%), Gaps = 86/578 (14%) Query: 60 DYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRS------- 112 DY++ P G G Y+Q G G P NRR S R R RS Sbjct: 165 DYQHGAAFGPPQG--GFHPPYWQPGPP----GPPAPPQNRRERPSSFRDRQRSPIALPVK 218 Query: 113 RSPKRRSVSSQRSRSRSRRS--YRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAE 170 + P + +R+ R + R + + +S +SK+ ++K T+ AE Sbjct: 219 QEPPQIDAVKRRTLPAWIREGLEKMEREKQKKLEKERMEQQRSQLSKK---EKKATEDAE 275 Query: 171 GEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPS 230 G P +SK F+ D E D N +A+SG + S P+ HS Sbjct: 276 GGDGPRLPQRSK--------FDSDEEEE-DTENVEAASSGKVTRSPSPV---PQEEHSDP 323 Query: 231 PIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNS 290 + + ML T T + + + + Sbjct: 324 EMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKDA---------------------- 361 Query: 291 PIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKSPP-----LHKN 345 H + ++PAK +A +A + GD E ++ + +S L Sbjct: 362 ---HRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHR 418 Query: 346 LDAREKSTFREESPLRI---KMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTL 402 + ++++ +R+E ++ K + + + E K + SL + R + Sbjct: 419 IRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDV 478 Query: 403 VHSVKKE-QEFRSIFD----HIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNE 457 V+ K+ E S+ + H + + +S S S S S + T++ Sbjct: 479 VNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSS-----SNSRTSSTSSTVSS 533 Query: 458 RFTSYQKATEEHSTRQKSPEIHRRIDIS--PSTLRKHTRLAGEERVFKEENQKGDKKLRC 515 S + S+R SP+ +R S P+ + +R R K E+ + K+R Sbjct: 534 SSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIR- 592 Query: 516 DSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKT-PKDYKEYKSYKDDSKHKREQD 574 DRRR R+ + + +R S R++ ++ +D + ++ + S+ +R+ D Sbjct: 593 ---------DRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKID 643 Query: 575 HSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKE 612 R + S S +E+E KKER + K+ Sbjct: 644 DQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKD 681 Score = 47.8 bits (112), Expect = 4e-05 Identities = 38/168 (22%), Positives = 74/168 (44%), Gaps = 15/168 (8%) Query: 2 GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDY 61 G + SH + +++ Q + RSRS + ++ + R R + + + + +D++ Sbjct: 647 GNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSS 706 Query: 62 RNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRR--S 119 +++R R+ R + R G V RH +S ++ K+ S Sbjct: 707 QDDRLKRKRESER------------TFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGS 754 Query: 120 VSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTK 167 SS RS S S S + ++ + SRS S KS S ++ S++ ++K Sbjct: 755 DSSGRSSSESPGSSKEKKAKKPKHSRSRS-VEKSQRSGKKASRKHKSK 801 Score = 45.8 bits (107), Expect = 1e-04 Identities = 53/226 (23%), Positives = 85/226 (37%), Gaps = 19/226 (8%) Query: 541 SRESSGSRKQEK--TPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKK 598 +RE+ G EK TP + K + K K +Q SRS SSS+ SS +SR S Sbjct: 471 AREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSST 530 Query: 599 EREEEFKTHHEMKEYSGFAGV-------SRPRGTFF---RIRGRGRARGVFAGTNTG--- 645 + + S + SR R R R R +R + +N Sbjct: 531 VSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVK 590 Query: 646 ---PNNSNTTFQKRPKEEEWDPEYTPKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGR 702 SN +R + P + + D R + R R + QRG Sbjct: 591 IRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLS 650 Query: 703 FN-FKKSGSSPKWTHDKYQGDGIVEDEEETMENNEEKKDRRKEEKE 747 N K G + + K + I +D ++ + E ++D+RKE+++ Sbjct: 651 GNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQK 696 Score = 45.8 bits (107), Expect = 1e-04 Identities = 52/209 (24%), Positives = 81/209 (38%), Gaps = 23/209 (11%) Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYR 62 R++ R++S S+ RSRSRS R R+ SRSRSRDR D R + Sbjct: 599 RNSIERERRRNRSPSRERRRSRSRSRDR--------RTNRASRSRSRDRRKIDDQRGNLS 650 Query: 63 NNRGMRRPYGYRGRGRGYYQGGGGRYHRG---GYRPVWNRRHSRSPRRGRSRSRSPKRRS 119 N ++ +G Q R + R +R + R K Sbjct: 651 GN-------SHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFK 703 Query: 120 VSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKR---RGSQEKQTKKAEGEPQEE 176 SSQ R + +R + S S S + SK+ + S++ + G E Sbjct: 704 FSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSE 763 Query: 177 SPLKSKSQEEPKDTFEHDPSESIDEFNKS 205 SP SK ++ K +H S S+++ +S Sbjct: 764 SPGSSKEKKAKKP--KHSRSRSVEKSQRS 790 Score = 45.1 bits (105), Expect = 2e-04 Identities = 39/154 (25%), Positives = 72/154 (46%), Gaps = 18/154 (11%) Query: 470 STRQKSPEIHRRIDISPSTL----RKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDID 525 ++R +S + R+ID L KH A E+ KE ++ DK + + + D Sbjct: 631 ASRSRSRD-RRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQD 689 Query: 526 RRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSY---------KDDSKHKREQD-- 574 +R++++ +E D K S + +++ ++ + + S + DSK +D Sbjct: 690 KRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSK 749 Query: 575 -HSRSSSSSASPS-SPSSREEKESKKEREEEFKT 606 HS S SS S S SP S +EK++KK + ++ Sbjct: 750 KHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRS 783 Score = 43.5 bits (101), Expect = 7e-04 Identities = 103/473 (21%), Positives = 160/473 (33%), Gaps = 63/473 (13%) Query: 133 YRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFE 192 Y S S S R S R ++KQ E +E+ L K EE K E Sbjct: 391 YGSGDSEDERSDRGSESSDTDDEELRHRIRQKQEAFWRKE-KEQQLLHDKQMEEEKQQTE 449 Query: 193 HDPSESIDEFNKSSATSGDIWPGLSA----YDNSPRSPHSPSPIATPPSQSSSCSDAPML 248 E ++EF S + A + R+P+ + + P + Sbjct: 450 RVTKE-MNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRS 508 Query: 249 STVHSAKNTPSQHSH-SIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAP 307 + S+ + S +S S S S S S +GSSR S +SP RS + TI Sbjct: 509 RSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTI-- 566 Query: 308 QNAPRDESRGRSSFYPDGGDQETAKTGKFLKSPPLHKNLDAREKSTFREESPLRIKMIAS 367 A R SR S ++ K +S N ++ E+ R SP R Sbjct: 567 -KARRSRSRSYSRRIKIESNRARVKIRDRRRS-----NRNSIERERRRNRSPSR------ 614 Query: 368 DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS 427 + R S ++DR T S + ++ R I D Q Sbjct: 615 -----------------ERRRSRSRSRDR---RTNRASRSRSRDRRKIDD-----QRGNL 649 Query: 428 TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS 487 + S + K++ +S ++ ++ ++ +QK E + Sbjct: 650 SGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDD 709 Query: 488 TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS 547 L++ ER F K +R HD + K +S + K S S Sbjct: 710 RLKRKRE---SERTFSRSGSISVKIIR-------HDSRQDSK-KSTTKDSKKHSGSDSSG 758 Query: 548 RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKER 600 R ++P KE K+ K KH R SRS S +SR+ K + R Sbjct: 759 RSSSESPGSSKEKKAKK--PKHSR----SRSVEKSQRSGKKASRKHKSKSRSR 805 Score = 34.3 bits (77), Expect = 0.43 Identities = 17/48 (35%), Positives = 28/48 (58%) Query: 2 GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSR 49 GRS+S S S + +++ SRSRS + +R ++ + S+SRSR Sbjct: 758 GRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKSRSR 805 Score = 31.6 bits (70), Expect = 2.8 Identities = 19/59 (32%), Positives = 31/59 (52%), Gaps = 1/59 (1%) Query: 5 NSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRN 63 +S+ HS S S +SSS S S +K + SRSR+ +S+ + SR ++ R+ Sbjct: 747 DSKKHSG-SDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKSRS 804 >gi|133922600 splicing factor, arginine/serine-rich 16 [Homo sapiens] Length = 674 Score = 88.6 bits (218), Expect = 2e-17 Identities = 85/224 (37%), Positives = 105/224 (46%), Gaps = 37/224 (16%) Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKR----YSS----RSRSRTYSRSRSRDRMYS 54 R +S S SS S SR+ SSSRS SRS SR +R Y S RSRSR++SRSRSR R YS Sbjct: 375 RRSSSSSSSSSASRT-SSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYS 433 Query: 55 RDYRRDYRNNRG-------------MRRPYGYRGRGRGYYQGGGGRYHRGG--------- 92 R R R++ G R YG R R R G RY RGG Sbjct: 434 RSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRS-RSHSGDRYRRGGRGLRHHSSS 492 Query: 93 -YRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSR-SSSPY 150 R W+ SRS RSRS SP S S RSRSRSR S R +R ++SP Sbjct: 493 RSRSSWSLSPSRSRSLTRSRSHSP---SPSQSRSRSRSRSQSPSPSPAREKLTRPAASPA 549 Query: 151 SKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHD 194 + K + K+T A+ + + LK + Q+ F+ D Sbjct: 550 VGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKAD 593 Score = 56.2 bits (134), Expect = 1e-07 Identities = 108/487 (22%), Positives = 187/487 (38%), Gaps = 84/487 (17%) Query: 110 SRSRSPKRRSVSSQRSRSRSRRSYRSSR------SPRSSSSRSSSPYSKSPVSKRRGSQE 163 +++ ++ S +RSR R RR +R R SP S + R S Y S S E Sbjct: 252 AKALEEEKAMYSGRRSR-RQRREFREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSSE 310 Query: 164 KQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSP 223 +++ P E K TF S DE ++A + + +P Sbjct: 311 SRSRSRSPTPGREE----------KITFITSFGGS-DEEAAAAAAAAAASGVTTGKPPAP 359 Query: 224 RSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSR 283 P P+P ++ S S S+ SA T S S S S R G G +G Sbjct: 360 PQPGGPAPGRNASARRRSSSS----SSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHA 415 Query: 284 YSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKSPPLH 343 S S++ SRR R SRGR + GG ++ + + +SP Sbjct: 416 RSRSRSWSRSRSRSRRYS----------RSRSRGRR--HSGGGSRDGHR---YSRSPARR 460 Query: 344 KNLDAREKSTFREESPLRIK-----MIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLL 398 R +S R S R + + S R ++P +R SLT+ R Sbjct: 461 GGYGPRRRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSP------SRSRSLTRSR-- 512 Query: 399 ASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAM-TLNE 457 H P S+S S S Q +E+ + AA + E Sbjct: 513 ------------------SHSPSPSQSRSRSRSRSQS--PSPSPAREKLTRPAASPAVGE 552 Query: 458 RFTSYQKATEEHSTRQK---SPEIHRRIDISPSTLR--KHTRLAGEERVFKEENQKGDKK 512 + + A + + K +P+ ++ + + R K + A +E++ ++E+++ +++ Sbjct: 553 KLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQERE 612 Query: 513 --LRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHK 570 LR + +R +R R+E+ +E + + SR+S + +P+ +EY S + S+ + Sbjct: 613 DELRAMARKIRMK-ERERREKEREEWERQYSRQS-----RSPSPRYSREYSSSRRRSRSR 666 Query: 571 REQDHSR 577 H R Sbjct: 667 SRSPHYR 673 Score = 39.7 bits (91), Expect = 0.010 Identities = 49/182 (26%), Positives = 68/182 (37%), Gaps = 35/182 (19%) Query: 4 SNSRSHSSRSKSRSQSSSRSRSRSHS---RKKRYSSRSRSRTYSRSRSRDRM-------- 52 S+SRS SS S S S+S S +RSRSHS + R SRSRS++ S S +R+++ Sbjct: 490 SSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASPA 549 Query: 53 ----------------------YSRDYRRDYRNNRGMRRPY--GYRGRGRGYYQGGGGRY 88 + + R + + R + + Q R Sbjct: 550 VGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQ 609 Query: 89 HRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSS 148 R R+ R R + R R S Q R S S S R S SRS S Sbjct: 610 EREDELRAMARKIRMKERERREKEREEWERQYSRQSRSPSPRYSREYSSSRRRSRSRSRS 669 Query: 149 PY 150 P+ Sbjct: 670 PH 671 Score = 32.0 bits (71), Expect = 2.2 Identities = 18/53 (33%), Positives = 25/53 (47%) Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSR 55 R+ +R + + R + R +SR+ R S SR YS SR R R SR Sbjct: 616 RAMARKIRMKERERREKEREEWERQYSRQSRSPSPRYSREYSSSRRRSRSRSR 668 Score = 30.0 bits (66), Expect = 8.2 Identities = 35/139 (25%), Positives = 51/139 (36%), Gaps = 11/139 (7%) Query: 459 FTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEE--RVFKEENQKGDKKLRCD 516 + S + A + +S RR S S R+H+ + R + ++G R Sbjct: 409 YRSGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRR 468 Query: 517 SADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKRE--QD 574 S H DR R+ +G R S SR + +S H Q Sbjct: 469 SRSRSHSGDRYRR-------GGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQS 521 Query: 575 HSRSSSSSASPSSPSSREE 593 SRS S S SPS +RE+ Sbjct: 522 RSRSRSRSQSPSPSPAREK 540 >gi|116089325 splicing factor, arginine/serine-rich 12 isoform a [Homo sapiens] Length = 624 Score = 85.5 bits (210), Expect = 2e-16 Identities = 89/334 (26%), Positives = 135/334 (40%), Gaps = 52/334 (15%) Query: 2 GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDY 61 G+SN R RS+S ++S SRS S+SHSR+KR S+ RSR+++RSRSR Sbjct: 298 GKSNERK-GGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQ----------- 345 Query: 62 RNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVS 121 ++ R + P+ R + R R +R HSR R+ K R Sbjct: 346 KDRRRSKSPHKKRSKSR-------------ERRKSRSRSHSRDKRKDTREKIKEKERVKE 392 Query: 122 SQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKS 181 R + R R R R + K + +E++ +K + +++ K Sbjct: 393 KDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKE--KE 450 Query: 182 KSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSS 241 K Q++ K+ E D S+ IDE K S P S Y+ S RS S S+SSS Sbjct: 451 KEQDKEKER-EKDRSKEIDEKRKKDKKSRT--PPRS-YNASRRSRSSSRERRRRRSRSSS 506 Query: 242 CSDAPMLSTVHSAKNTPSQHSHS------------IQHSPERSGSGSVGNGSS------- 282 S + + +PS S + I ER S S+ S+ Sbjct: 507 RSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEK 566 Query: 283 --RYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDE 314 + S S H+ S +K + ++APR E Sbjct: 567 LEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTE 600 Score = 52.4 bits (124), Expect = 2e-06 Identities = 67/297 (22%), Positives = 115/297 (38%), Gaps = 30/297 (10%) Query: 463 QKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRH 522 + +++ HS R++S HR + S R+ R + K + +K R S Sbjct: 317 RSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDK 376 Query: 523 DIDRRRKERSKER---GDSKGSRESSGSRKQEK---------TPKDYKEYKSYKDDSKHK 570 D R K + KER D + RE R++EK ++ K + D + + Sbjct: 377 RKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERE 436 Query: 571 REQDHSRSSSSSASPSSPSSRE-EKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFFRI 629 RE++H + +E EK+ KE +E+ K + + SR + R Sbjct: 437 REKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRE 496 Query: 630 RGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYTPKSKKYFLHDDRDDGVDYWAKR 689 R R R+R ++ P S T +K + P ++KK + D + +R Sbjct: 497 RRRRRSR----SSSRSPRTSKTIKRKSSR----SPSPRSRNKKDKKREKERDHIS--ERR 546 Query: 690 GRGRGTFQRGR-----GRFNFKKSGSSPKWTHDKYQGDGIV--EDEEETMENNEEKK 739 R R T R G+ +K+ +S K + D V E +++ EE K Sbjct: 547 ERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENK 603 Score = 48.9 bits (115), Expect = 2e-05 Identities = 60/267 (22%), Positives = 101/267 (37%), Gaps = 15/267 (5%) Query: 348 AREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVK 407 + E+ R S R K +S K + NR S KDR + + Sbjct: 300 SNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRS 359 Query: 408 KEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATE 467 K +E R K T E + VKE+ + ER +K Sbjct: 360 KSRERRKSRSRSHSRDKRKDTREKIKEK-----ERVKEKDREKEREREKER--EKEKERG 412 Query: 468 EHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRR 527 ++ R K E R D R+ + ++R ++E ++ +K R D +ID + Sbjct: 413 KNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKER--EKDRSKEIDEK 470 Query: 528 RKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSS 587 RK+ K R R + SR+ + ++ + +S + + R SS S S Sbjct: 471 RKKDKKSR---TPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRS---PS 524 Query: 588 PSSREEKESKKEREEEFKTHHEMKEYS 614 P SR +K+ K+E+E + + +E S Sbjct: 525 PRSRNKKDKKREKERDHISERRERERS 551 Score = 48.1 bits (113), Expect = 3e-05 Identities = 34/122 (27%), Positives = 53/122 (43%), Gaps = 5/122 (4%) Query: 95 PVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSP 154 P + + R R RS +RS R S S R RS+ +RS RS S + SKSP Sbjct: 295 PESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSP 354 Query: 155 VSKRRGSQEKQTKKAEGEPQEE-----SPLKSKSQEEPKDTFEHDPSESIDEFNKSSATS 209 KR S+E++ ++ +++ +K K + + KD + E E K + Sbjct: 355 HKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKN 414 Query: 210 GD 211 D Sbjct: 415 KD 416 Score = 45.8 bits (107), Expect = 1e-04 Identities = 83/402 (20%), Positives = 153/402 (38%), Gaps = 46/402 (11%) Query: 215 GLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGS 274 G+ D + HS + I PP + + + + + S S +I+ PE S Sbjct: 243 GVMFGDRPLKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIE--PESGKS 300 Query: 275 GSVGNGSSRY---SPSQNSPIHHIPSRRSPAKTIA-----PQNAPRDESRGRSSFYPDGG 326 G SR S S++S H +RS +K + ++ +D R +S Sbjct: 301 NERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSK 360 Query: 327 DQETAKTGKFLKSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDS 386 +E K+ +S K D REK +E+ ++ K + R + + K + Sbjct: 361 SRERRKSRS--RSHSRDKRKDTREK--IKEKERVKEKDREKEREREKEREK-------EK 409 Query: 387 NRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQ 446 R + +D+ +K++E +H K K + +++ Sbjct: 410 ERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQD-----------KEKE 458 Query: 447 YFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEEN 506 K + ++E+ +K ++ T +S RR S S R+ R R + Sbjct: 459 REKDRSKEIDEK----RKKDKKSRTPPRSYNASRR-SRSSSRERRRRRSRSSSRSPRTSK 513 Query: 507 QKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDD 566 K R S R+ D++R E+ ++ + RE S S ++ +D KE + + Sbjct: 514 TIKRKSSRSPSPRSRNKKDKKR-EKERDHISERRERERSTSMRKSSNDRDGKE--KLEKN 570 Query: 567 SKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHH 608 S +E++H++ P S S+E + R EE K H Sbjct: 571 STSLKEKEHNKE------PDSSVSKEVDDKDAPRTEENKIQH 606 Score = 37.4 bits (85), Expect = 0.051 Identities = 50/211 (23%), Positives = 80/211 (37%), Gaps = 37/211 (17%) Query: 537 DSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKES 596 +S S E G R + T K S K S+ KR Q RS S + S S ++ + S Sbjct: 296 ESGKSNERKGGRSRSHTRS--KSRSSSKSHSRRKRSQSKHRSRSHNRSRS--RQKDRRRS 351 Query: 597 KKEREEEFKTHHEMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKR 656 K ++ K+ K S + + T +I+ + R + + R Sbjct: 352 KSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKE----------------KDR 395 Query: 657 PKEEEWDPEYTPKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTH 716 KE E + E K K+ + DRD +R + R K+ + Sbjct: 396 EKEREREKE-REKEKERGKNKDRDK---------------EREKDREKDKEK-DRERERE 438 Query: 717 DKYQGDGIVEDEEETMENNEEKKDRRKEEKE 747 +++ D E E+E + E +KDR KE E Sbjct: 439 KEHEKDRDKEKEKEQDKEKEREKDRSKEIDE 469 Score = 35.4 bits (80), Expect = 0.19 Identities = 35/152 (23%), Positives = 57/152 (37%), Gaps = 20/152 (13%) Query: 464 KATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHD 523 K EE R + + I P + + + R G R + K Sbjct: 273 KELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSH--------- 323 Query: 524 IDRRRKERSKERGDSKG-SRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSS 582 RR++ +SK R S SR R++ K+P K +R + SRS S Sbjct: 324 -SRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHK-------KRSKSRERRKSRSRSHSRD 375 Query: 583 ASPSSPSSREEKE--SKKEREEEFKTHHEMKE 612 + +EKE +K+RE+E + E ++ Sbjct: 376 KRKDTREKIKEKERVKEKDREKEREREKEREK 407 >gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [Homo sapiens] Length = 508 Score = 85.5 bits (210), Expect = 2e-16 Identities = 89/334 (26%), Positives = 135/334 (40%), Gaps = 52/334 (15%) Query: 2 GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDY 61 G+SN R RS+S ++S SRS S+SHSR+KR S+ RSR+++RSRSR Sbjct: 182 GKSNERK-GGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQ----------- 229 Query: 62 RNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVS 121 ++ R + P+ R + R R +R HSR R+ K R Sbjct: 230 KDRRRSKSPHKKRSKSR-------------ERRKSRSRSHSRDKRKDTREKIKEKERVKE 276 Query: 122 SQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKS 181 R + R R R R + K + +E++ +K + +++ K Sbjct: 277 KDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKE--KE 334 Query: 182 KSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSS 241 K Q++ K+ E D S+ IDE K S P S Y+ S RS S S+SSS Sbjct: 335 KEQDKEKER-EKDRSKEIDEKRKKDKKSRT--PPRS-YNASRRSRSSSRERRRRRSRSSS 390 Query: 242 CSDAPMLSTVHSAKNTPSQHSHS------------IQHSPERSGSGSVGNGSS------- 282 S + + +PS S + I ER S S+ S+ Sbjct: 391 RSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEK 450 Query: 283 --RYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDE 314 + S S H+ S +K + ++APR E Sbjct: 451 LEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTE 484 Score = 52.4 bits (124), Expect = 2e-06 Identities = 67/297 (22%), Positives = 115/297 (38%), Gaps = 30/297 (10%) Query: 463 QKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRH 522 + +++ HS R++S HR + S R+ R + K + +K R S Sbjct: 201 RSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDK 260 Query: 523 DIDRRRKERSKER---GDSKGSRESSGSRKQEK---------TPKDYKEYKSYKDDSKHK 570 D R K + KER D + RE R++EK ++ K + D + + Sbjct: 261 RKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERE 320 Query: 571 REQDHSRSSSSSASPSSPSSRE-EKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFFRI 629 RE++H + +E EK+ KE +E+ K + + SR + R Sbjct: 321 REKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRE 380 Query: 630 RGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYTPKSKKYFLHDDRDDGVDYWAKR 689 R R R+R ++ P S T +K + P ++KK + D + +R Sbjct: 381 RRRRRSR----SSSRSPRTSKTIKRKSSR----SPSPRSRNKKDKKREKERDHIS--ERR 430 Query: 690 GRGRGTFQRGR-----GRFNFKKSGSSPKWTHDKYQGDGIV--EDEEETMENNEEKK 739 R R T R G+ +K+ +S K + D V E +++ EE K Sbjct: 431 ERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENK 487 Score = 48.9 bits (115), Expect = 2e-05 Identities = 60/267 (22%), Positives = 101/267 (37%), Gaps = 15/267 (5%) Query: 348 AREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVK 407 + E+ R S R K +S K + NR S KDR + + Sbjct: 184 SNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRS 243 Query: 408 KEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATE 467 K +E R K T E + VKE+ + ER +K Sbjct: 244 KSRERRKSRSRSHSRDKRKDTREKIKEK-----ERVKEKDREKEREREKER--EKEKERG 296 Query: 468 EHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRR 527 ++ R K E R D R+ + ++R ++E ++ +K R D +ID + Sbjct: 297 KNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKER--EKDRSKEIDEK 354 Query: 528 RKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSS 587 RK+ K R R + SR+ + ++ + +S + + R SS S S Sbjct: 355 RKKDKKSR---TPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRS---PS 408 Query: 588 PSSREEKESKKEREEEFKTHHEMKEYS 614 P SR +K+ K+E+E + + +E S Sbjct: 409 PRSRNKKDKKREKERDHISERRERERS 435 Score = 48.1 bits (113), Expect = 3e-05 Identities = 34/122 (27%), Positives = 53/122 (43%), Gaps = 5/122 (4%) Query: 95 PVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSP 154 P + + R R RS +RS R S S R RS+ +RS RS S + SKSP Sbjct: 179 PESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSP 238 Query: 155 VSKRRGSQEKQTKKAEGEPQEE-----SPLKSKSQEEPKDTFEHDPSESIDEFNKSSATS 209 KR S+E++ ++ +++ +K K + + KD + E E K + Sbjct: 239 HKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKN 298 Query: 210 GD 211 D Sbjct: 299 KD 300 Score = 45.8 bits (107), Expect = 1e-04 Identities = 83/402 (20%), Positives = 153/402 (38%), Gaps = 46/402 (11%) Query: 215 GLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGS 274 G+ D + HS + I PP + + + + + S S +I+ PE S Sbjct: 127 GVMFGDRPLKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIE--PESGKS 184 Query: 275 GSVGNGSSRY---SPSQNSPIHHIPSRRSPAKTIA-----PQNAPRDESRGRSSFYPDGG 326 G SR S S++S H +RS +K + ++ +D R +S Sbjct: 185 NERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSK 244 Query: 327 DQETAKTGKFLKSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDS 386 +E K+ +S K D REK +E+ ++ K + R + + K + Sbjct: 245 SRERRKSRS--RSHSRDKRKDTREK--IKEKERVKEKDREKEREREKEREK-------EK 293 Query: 387 NRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQ 446 R + +D+ +K++E +H K K + +++ Sbjct: 294 ERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQD-----------KEKE 342 Query: 447 YFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEEN 506 K + ++E+ +K ++ T +S RR S S R+ R R + Sbjct: 343 REKDRSKEIDEK----RKKDKKSRTPPRSYNASRR-SRSSSRERRRRRSRSSSRSPRTSK 397 Query: 507 QKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDD 566 K R S R+ D++R E+ ++ + RE S S ++ +D KE + + Sbjct: 398 TIKRKSSRSPSPRSRNKKDKKR-EKERDHISERRERERSTSMRKSSNDRDGKE--KLEKN 454 Query: 567 SKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHH 608 S +E++H++ P S S+E + R EE K H Sbjct: 455 STSLKEKEHNKE------PDSSVSKEVDDKDAPRTEENKIQH 490 Score = 37.4 bits (85), Expect = 0.051 Identities = 50/211 (23%), Positives = 80/211 (37%), Gaps = 37/211 (17%) Query: 537 DSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKES 596 +S S E G R + T K S K S+ KR Q RS S + S S ++ + S Sbjct: 180 ESGKSNERKGGRSRSHTRS--KSRSSSKSHSRRKRSQSKHRSRSHNRSRS--RQKDRRRS 235 Query: 597 KKEREEEFKTHHEMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKR 656 K ++ K+ K S + + T +I+ + R + + R Sbjct: 236 KSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKE----------------KDR 279 Query: 657 PKEEEWDPEYTPKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTH 716 KE E + E K K+ + DRD +R + R K+ + Sbjct: 280 EKEREREKE-REKEKERGKNKDRDK---------------EREKDREKDKEK-DRERERE 322 Query: 717 DKYQGDGIVEDEEETMENNEEKKDRRKEEKE 747 +++ D E E+E + E +KDR KE E Sbjct: 323 KEHEKDRDKEKEKEQDKEKEREKDRSKEIDE 353 Score = 35.4 bits (80), Expect = 0.19 Identities = 35/152 (23%), Positives = 57/152 (37%), Gaps = 20/152 (13%) Query: 464 KATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHD 523 K EE R + + I P + + + R G R + K Sbjct: 157 KELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSH--------- 207 Query: 524 IDRRRKERSKERGDSKG-SRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSS 582 RR++ +SK R S SR R++ K+P K +R + SRS S Sbjct: 208 -SRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHK-------KRSKSRERRKSRSRSHSRD 259 Query: 583 ASPSSPSSREEKE--SKKEREEEFKTHHEMKE 612 + +EKE +K+RE+E + E ++ Sbjct: 260 KRKDTREKIKEKERVKEKDREKEREREKEREK 291 >gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] Length = 484 Score = 80.9 bits (198), Expect = 4e-15 Identities = 71/241 (29%), Positives = 108/241 (44%), Gaps = 26/241 (10%) Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYR 62 + R HS RS+SRS+ R R+ S SR +R SRSR R++S+SRSR R S RR + Sbjct: 242 KEEKRRHS-RSRSRSR---RRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHS 297 Query: 63 NNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSS 122 RG R + R + + ++ S++P + S +R + RS S Sbjct: 298 RERGRRSRSTSKTRDK--------------KKEDKEKKRSKTPPKSYSTAR--RSRSASR 341 Query: 123 QRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSK 182 +R R RSR RS + PRS + S+SP S RR +EK+ K + ++E + Sbjct: 342 ERRRRRSRSGTRSPKKPRSPKRK----LSRSP-SPRRHKKEKKKDKDKERSRDERERSTS 396 Query: 183 SQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSC 242 +++ KD E D + + D YD+ PI T ++ C Sbjct: 397 KKKKSKDK-EKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKEC 455 Query: 243 S 243 S Sbjct: 456 S 456 Score = 51.2 bits (121), Expect = 3e-06 Identities = 66/302 (21%), Positives = 118/302 (39%), Gaps = 21/302 (6%) Query: 372 PEVKLKMAPVPLDDSN-RPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSE 430 P + +A + L +N SL D+LL L+ +V + + + + P TS Sbjct: 161 PTLDPALAALGLPGANLNSQSLAADQLLK--LMSTV--DPKLNHVAAGLVSPSLKSDTSS 216 Query: 431 SFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLR 490 I+ + V Q SAA+ ++ K + +R +S RR +PS+ R Sbjct: 217 KEIEEAMKRVREA--QSLISAAIEPDK------KEEKRRHSRSRSRSRRRR---TPSSSR 265 Query: 491 KHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQ 550 H R R + + K + R S R R R RS+ ++ ++ +K+ Sbjct: 266 -HRRSRSRSR--RRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKR 322 Query: 551 EKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEM 610 KTP K Y + + RE+ RS S + SP P S + K S+ K + Sbjct: 323 SKTPP--KSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKK 380 Query: 611 KEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYTPKS 670 + + R R T + + + + + + + + T +E+ +D E K Sbjct: 381 DKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKE 440 Query: 671 KK 672 +K Sbjct: 441 EK 442 Score = 51.2 bits (121), Expect = 3e-06 Identities = 51/231 (22%), Positives = 88/231 (38%), Gaps = 24/231 (10%) Query: 517 SADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHS 576 SA + D ++ S+ R S+ R S SR + + + S + + Sbjct: 234 SAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRR 293 Query: 577 RSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFFRIRGRGRAR 636 RS S S S+ + ++ KKE +E+ ++ K YS +R + R R R R+R Sbjct: 294 RSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYS----TARRSRSASRERRRRRSR 349 Query: 637 GVFAGTNTGPNNSNTTFQKRPKEEEWDPEYTPKSKKYFLHDDRDDGVDYWAKRGRGRGTF 696 S T K+P+ + +P +++ +D + + R Sbjct: 350 ------------SGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKD--------KDKERSRD 389 Query: 697 QRGRGRFNFKKSGSSPKWTHDKYQGDGIVEDEEETMENNEEKKDRRKEEKE 747 +R R KKS K K + D V+ + E+ D KE+KE Sbjct: 390 ERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKE 440 Score = 42.4 bits (98), Expect = 0.002 Identities = 35/161 (21%), Positives = 65/161 (40%), Gaps = 11/161 (6%) Query: 449 KSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQK 508 KS + R S ++ + +SP+ R S RK +R R KE+ + Sbjct: 328 KSYSTARRSRSASRERRRRRSRSGTRSPKKPR------SPKRKLSRSPSPRRHKKEKKKD 381 Query: 509 GDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSK 568 DK+ D + ++ K++ K+R R+S + ++ +DY E + D K Sbjct: 382 KDKERSRDERERSTSKKKKSKDKEKDR-----ERKSESDKDVKQVTRDYDEEEQGYDSEK 436 Query: 569 HKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHE 609 K+E+ + S + + +S +E + HHE Sbjct: 437 EKKEEKKPIETGSPKTKECSVEKGTGDSLRESKVNGDDHHE 477 Score = 35.0 bits (79), Expect = 0.25 Identities = 35/165 (21%), Positives = 65/165 (39%), Gaps = 13/165 (7%) Query: 442 HVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERV 501 H +E+ +S + + K + T KS RR + R+ +G Sbjct: 296 HSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSP 355 Query: 502 FKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYK 561 K + K +KL + RH ++ K++ K++ S+ RE S S+K K+ K Sbjct: 356 KKPRSPK--RKLSRSPSPRRH---KKEKKKDKDKERSRDERERSTSKK--------KKSK 402 Query: 562 SYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKT 606 + D + K E D + + ++ KKE ++ +T Sbjct: 403 DKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIET 447 >gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] Length = 904 Score = 80.5 bits (197), Expect = 5e-15 Identities = 153/655 (23%), Positives = 242/655 (36%), Gaps = 118/655 (18%) Query: 23 SRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNNRGMRRPYGYRGRGRGYYQ 82 S+ K R SRSRS++ SR+RSR ++R RR +R R R Y Sbjct: 265 SKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRR-------------HRSRSRSY-- 309 Query: 83 GGGGRYHRGGYRPVWNRRHSRSPRRGRS-RSRSPKRR---SVSSQRSRSRSRRSYRSSRS 138 + R SPRR S R R+P RR +RSRS RR RSS S Sbjct: 310 ---------------SPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSAS 354 Query: 139 PRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDT----FEHD 194 SSS SSS S+SP K +K SP + + + P T H Sbjct: 355 LSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHS 414 Query: 195 PSESIDEFNKSSATSGDIWPGLSA----YDNSPRSPHSPSPIATPPSQSSSCSDAPMLST 250 P+ + N++ + + PG ++ SPSP P S S+ Sbjct: 415 PTP--QQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGK 472 Query: 251 VHSAKNTPSQHSHSIQHSPERSGSGS-------------VGNGS----SRYSPSQN-SPI 292 + +A + + + Q+ S SGS V NG R+SPS++ SP Sbjct: 473 MAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPS 532 Query: 293 --------------HHIPS------RRSPAKTIAP--QNAPRDESRGRSSFYPDGGDQET 330 PS RRSP+ P + P R R+ P + Sbjct: 533 PRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPS 592 Query: 331 AKTGKFLKSPPLHKNLDAREKSTFREES-PLRIKMIASDSHRPEVKLKMAPVPLDDSNRP 389 + SPP+ + R S P K AS S P+ ++ +P P R Sbjct: 593 PRR----YSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPP---KQRS 645 Query: 390 ASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFK 449 + +TK R + + H K RS + + PQ +K S S + Sbjct: 646 SPVTKRRSPSLSSKHR-KGSSPSRSTRE-ARSPQPNKRHSPSPRPRAPQT--SSSPPPVR 701 Query: 450 SAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKG 509 A + +R S +T ++PE ++I + S + R R + Sbjct: 702 RGASSSPQRRQSPSPSTRPIRRVSRTPE-PKKIKKAASPSPQSVRRVSSSRSVSGSPEPA 760 Query: 510 DKKLRCDSADLRHD-----------IDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYK 558 KK + ++ + + + +E G +K++K K +K Sbjct: 761 AKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHK 820 Query: 559 EYKSYKDDSKHKREQDHSRSSSSSASPSSPS------SREE----KESKKEREEE 603 + K +K KHK+E+ + +++++ +P++ + ++EE E KKE E E Sbjct: 821 KDKKHKKHKKHKKEKAVAAAAAAAVTPAAIAAATTTLAQEEPVAAPEPKKETESE 875 Score = 74.3 bits (181), Expect = 4e-13 Identities = 149/649 (22%), Positives = 235/649 (36%), Gaps = 105/649 (16%) Query: 27 SHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNNRGMRRPYGYRGRGRGYYQGGGG 86 S K++ +R RSR+ S+SRSR R S + R R +R R Y R R Sbjct: 265 SKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRP--------- 315 Query: 87 RYHRGGYRPVWNRRHSRSPRRGRS-RSRSPKRRSVSS---QRSRSRSRRSYRSSRSPRSS 142 SPRR S R R+P RR +RSRS RR RSS S S Sbjct: 316 -----------------SPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGS 358 Query: 143 SSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDT----FEHDPSES 198 SS SSS S+SP K +K SP + + + P T H P+ Sbjct: 359 SSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQ 418 Query: 199 IDEFNKSSATSGDIWPGLSA----YDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSA 254 + N++ + + PG ++ SPSP P S S+ + +A Sbjct: 419 --QSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAA 476 Query: 255 KNTPSQHSHSIQHSPERSGSGS-------------VGNGS----SRYSPSQN-SPI---- 292 + + + Q+ S SGS V NG R+SPS++ SP Sbjct: 477 DSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKR 536 Query: 293 ----------HHIPS------RRSPAKTIAPQN--APRDESRGRSSFYPDGGDQETAKTG 334 PS RRSP+ P+ P R R+ P + + Sbjct: 537 QKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRR- 595 Query: 335 KFLKSPPLHKNLDAREKSTFREESPLRI-KMIASDSHRPEVKLKMAPVPLDDSNRPASLT 393 SPP+ + R SP K AS S P+ ++ +P P R + +T Sbjct: 596 ---YSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPP---KQRSSPVT 649 Query: 394 KDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAM 453 K R + + H K RS + + PQ +K S S + A Sbjct: 650 KRRSPSLSSKHR-KGSSPSRSTRE-ARSPQPNKRHSPSPRPRAPQTSSSPPP--VRRGAS 705 Query: 454 TLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKL 513 + +R S +T ++PE ++I + S + R R + KK Sbjct: 706 SSPQRRQSPSPSTRPIRRVSRTPE-PKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKP 764 Query: 514 RCDSADLRHDID----------RRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSY 563 + ++ ++ K + + S + G +K++K K K++K Sbjct: 765 PAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKK--KKDKKHKKD 822 Query: 564 KDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKE 612 K KHK+ + ++++A+ +P++ + +EE KE Sbjct: 823 KKHKKHKKHKKEKAVAAAAAAAVTPAAIAAATTTLAQEEPVAAPEPKKE 871 Score = 67.0 bits (162), Expect = 6e-11 Identities = 108/433 (24%), Positives = 160/433 (36%), Gaps = 81/433 (18%) Query: 99 RRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPR-SSSSRSSSP----YSKS 153 R SRSPRR +SRS SP+RRS +R R RS SRSPR + SRS SP K+ Sbjct: 166 RERSRSPRRRKSRSPSPRRRSSPVRRERKRSH-----SRSPRHRTKSRSPSPAPEKKEKT 220 Query: 154 P------VSKRRGSQEKQTKKAE----------GEPQEESPLKSKSQEEPKDTFEHDPSE 197 P V + S ++ T ++ EP+E SP K+ +E+ K E Sbjct: 221 PELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEK--------E 272 Query: 198 SIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNT 257 ++S + S S PR H + P + S P + Sbjct: 273 KTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRM 332 Query: 258 PSQHSHSIQHSP----ERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS--PAKT--IAPQ- 308 P H SP RS + G+ SS S SP P R S P KT ++P Sbjct: 333 PPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSA 392 Query: 309 NAPRDESR--------GRSSFYPDGGDQETAKTGKFLKSPPLHKNLDAREKSTFREESPL 360 + PR R ++ P + + SP + K T + ESP Sbjct: 393 SPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESP- 451 Query: 361 RIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIK 420 S + +P K++++ D + A+ SV++ +++R Sbjct: 452 ------SPAPKPR-KVELSESEEDKGGKMAA-----------ADSVQQRRQYRRQNQQSS 493 Query: 421 LPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQK--SPEI 478 S S+SE K + K+ + R + + A+ RQK SP Sbjct: 494 SDSGSSSSSED---------ERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRG 544 Query: 479 HRRIDISPSTLRK 491 RR SP R+ Sbjct: 545 RRRRSPSPPPTRR 557 Score = 58.9 bits (141), Expect = 2e-08 Identities = 107/495 (21%), Positives = 172/495 (34%), Gaps = 88/495 (17%) Query: 110 SRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSK-SPVSKRRGSQEKQTKK 168 S + + + + + SR SRSPR SRS SP + SPV + R ++ + Sbjct: 143 SMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPR 202 Query: 169 AEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHS 228 + + SP K ++ P+ +PS + E + ATS + + P P Sbjct: 203 HRTKSRSPSPAPEKKEKTPE---LPEPSVKVKEPSVQEATSTSDILKVPKPEPIP-EPKE 258 Query: 229 PSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHS-PERSGSGSVGNGSSRYSPS 287 PSP + P + +K+ S S H+ P R + S R PS Sbjct: 259 PSPEKNSKKEKEKEKTRPRSRS--RSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPS 316 Query: 288 ---QNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKSPPLHK 344 + SP P RR P ++ R RSS G ++ + +SPP Sbjct: 317 PRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRS--RSPP--- 371 Query: 345 NLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVH 404 +K R SP R S S P + + P P P T+ Sbjct: 372 -----KKPPKRTSSPPRKTRRLSPSASPP-RRRHRPSP---PATPPPKTR---------- 412 Query: 405 SVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQK 464 H PQ S T +S + S + + K Sbjct: 413 -------------HSPTPQQSNRTRKSRV----------------SVSPGRTSGKVTKHK 443 Query: 465 ATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAG-----EERVFKEENQKGDKKLRCDSAD 519 TE+ + +P+ R++++S S K ++A + R ++ +NQ+ DS Sbjct: 444 GTEKRESPSPAPK-PRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSS----DSGS 498 Query: 520 LRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSS 579 D R K + G+ R S SR +P+ KR+++ S Sbjct: 499 SSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPR--------------KRQKETSPRG 544 Query: 580 SSSASPSSPSSREEK 594 SPS P +R + Sbjct: 545 RRRRSPSPPPTRRRR 559 Score = 53.1 bits (126), Expect = 9e-07 Identities = 82/284 (28%), Positives = 112/284 (39%), Gaps = 42/284 (14%) Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRS-----RDRMYSRDY 57 RS S S R K S R RS S +R S S + R R+ R R S Sbjct: 527 RSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPP 586 Query: 58 RRDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSP--RRGRSRSRSP 115 RR + R P R Y + P RR S SP +R S S P Sbjct: 587 RRRSPSPRRYSPPIQRR-----YSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPP 641 Query: 116 KRRS--VSSQRSRSRSR---------RSYRSSRSPRSSSSRSSSPY------SKSPVSKR 158 K+RS V+ +RS S S RS R +RSP+ + S SP S SP R Sbjct: 642 KQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVR 701 Query: 159 RGSQEKQTKKAEGEPQEESPLK--SKSQEEPKDTFEHDPS-ESIDEFNKSSATSGDIWPG 215 RG+ ++ P P++ S++ E K PS +S+ + S + SG P Sbjct: 702 RGASSSPQRRQSPSPSTR-PIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPA 760 Query: 216 LSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPS 259 + + P PSP+ SQS S + +P + + TPS Sbjct: 761 ------AKKPPAPPSPV---QSQSPSTNWSPAVPVKKAKSPTPS 795 Score = 49.3 bits (116), Expect = 1e-05 Identities = 83/379 (21%), Positives = 136/379 (35%), Gaps = 43/379 (11%) Query: 3 RSNSRSHSSRSK-SRSQSSSRSRSRSHSRKKRYSS--RSRSRTYSRS---RSRDRMYSRD 56 R SSR K RS+S R +SRS S ++R S R R R++SRS R++ R S Sbjct: 154 RDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPA 213 Query: 57 YRRDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPK 116 + + + P+ + + + K Sbjct: 214 PEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEK 273 Query: 117 RRSVSSQRSRSRSRRSYRS-----SRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEG 171 R S RS+SRSR RS R S SRS SP + P +RR S ++T Sbjct: 274 TRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSP-RRRPSPRRRPSPRRRTPPRRM 332 Query: 172 EP-----QEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSP 226 P + SP++ + + S S+ + SS++S P P+ P Sbjct: 333 PPPPRHRRSRSPVRRRRRS----------SASLSGSSSSSSSSRSRSP--------PKKP 374 Query: 227 HSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSP 286 P ++PP ++ S + + P+ +HSP S SP Sbjct: 375 --PKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSP 432 Query: 287 SQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQ----ETAKTGKFLKSPPL 342 + S + + K +P AP+ S D G + ++ + + + Sbjct: 433 GRTS--GKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQ 490 Query: 343 HKNLDAREKSTFREESPLR 361 + D+ S+ +E P R Sbjct: 491 QSSSDSGSSSSSEDERPKR 509 Score = 37.4 bits (85), Expect = 0.051 Identities = 31/121 (25%), Positives = 50/121 (41%), Gaps = 11/121 (9%) Query: 483 DISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLR------HDIDRRRKERSKERG 536 ++ P L +AG F E ++ K+ + + L D D+R KE KE Sbjct: 104 ELWPLLLSAQENIAGIPSAFLELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEE-KESS 162 Query: 537 DSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKES 596 K R S R++ ++P + + +R++ HSRS SPS EK+ Sbjct: 163 REKRERSRSPRRRKSRSPSPRRR----SSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKE 218 Query: 597 K 597 K Sbjct: 219 K 219 Score = 36.2 bits (82), Expect = 0.11 Identities = 56/238 (23%), Positives = 86/238 (36%), Gaps = 28/238 (11%) Query: 428 TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS 487 +++ I I S +K++ K + E+ S +K E+ R K + S Sbjct: 111 SAQENIAGIPSAFLELKKEEIKQRQIE-QEKLASMKKQDEDKDKRDKEEK--------ES 161 Query: 488 TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGD---SKGSRES 544 + K R R +K R S R RR ++RS R +K S Sbjct: 162 SREKRERSRSPRR----------RKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPS 211 Query: 545 SGSRKQEKTPKDYKEYKSYKDDSKHK--REQDHSRSSSSSASPSSPSSREEKESKKEREE 602 K+EKTP+ + K+ S + D + P EK SKKE+E+ Sbjct: 212 PAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEK 271 Query: 603 EFKTHHEMKEYSGFAGVSR---PRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRP 657 E KT + S +R P T R R R R+R P + ++ P Sbjct: 272 E-KTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTP 328 >gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] Length = 2426 Score = 79.7 bits (195), Expect = 9e-15 Identities = 69/203 (33%), Positives = 97/203 (47%), Gaps = 23/203 (11%) Query: 3 RSNSRSHSSRSKSRSQSS------SRSRSRSHSRKKRYSSRSRS-----RTYSRSRSRDR 51 +S R+ SRS++R +SS S++RSRS SR++R SSRSRS R+ S+ + + Sbjct: 1835 KSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRS 1894 Query: 52 MYSRDYRRDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSR 111 R R+ + R R R R R H RR SRS R RS Sbjct: 1895 PKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPS-----RRRRSRSVGRRRSF 1949 Query: 112 SRSPKRRS-VSSQRSRSRSRRSYRSSRSPRSSSSRSSSP--YSKSPVSKRRGSQEKQTKK 168 S SP RRS S+RSR+ SRRS SR R+ S RS +P S++P +RR + + Sbjct: 1950 SISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRS 2009 Query: 169 AEGEP----QEESPLKSKSQEEP 187 P + +PL+ + P Sbjct: 2010 FSISPVRLRRSRTPLRRRFSRSP 2032 Score = 79.0 bits (193), Expect = 2e-14 Identities = 79/227 (34%), Positives = 107/227 (47%), Gaps = 22/227 (9%) Query: 3 RSNSRSHSSRSKS-RSQSSSRSRSRSHSRKKRYSSRSRSRTY-----------SRSRSRD 50 RS +R SS+SKS RSQ+ SRSRSR R R S+SR R RS+SR+ Sbjct: 1844 RSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRE 1903 Query: 51 RMYSRDYRRDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWN---RRHSRSP-R 106 R R RD R R R R R + R G R ++ R SR+P R Sbjct: 1904 RKRKRSSSRDNRKTVRARSRTPSR-RSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSR 1962 Query: 107 RGRS---RSRSPKRRS-VSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQ 162 R R+ RSR+P RRS S+RSR+ SRRS SR RS S +S SPV RR Sbjct: 1963 RSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRT 2022 Query: 163 EKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATS 209 + + + + + S+ PK + D ++ + E K++A + Sbjct: 2023 PLRRRFSRSPIRRKRSRSSERGRSPKRLTDLDKAQLL-EIAKANAAA 2068 Score = 68.2 bits (165), Expect = 3e-11 Identities = 65/199 (32%), Positives = 91/199 (45%), Gaps = 27/199 (13%) Query: 3 RSNSRSHSSRSKSRSQSSSRSRSR-----SHSRKKRYSSRS---RSRTYSRSRSRDRMYS 54 + R S RS+S+ SS +SR S SR ++ SS+S RS+T SRSRSR R S Sbjct: 1814 KEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRS 1873 Query: 55 RDYRRDYRNNRGM---RRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSR 111 R R R + +R + R + + R + V R SR+P R RSR Sbjct: 1874 SRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTV--RARSRTPSR-RSR 1930 Query: 112 SRSPKRRSVS-------------SQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKR 158 S +P RR S S+RSR+ SRRS SR R+ S RS +P +S R Sbjct: 1931 SHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSR 1990 Query: 159 RGSQEKQTKKAEGEPQEES 177 R + +++ + S Sbjct: 1991 RSRTPSRRRRSRSVVRRRS 2009 Score = 63.2 bits (152), Expect = 9e-10 Identities = 75/256 (29%), Positives = 102/256 (39%), Gaps = 41/256 (16%) Query: 4 SNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRN 63 S+ RS S RSKS S + S S SR ++ SS+S+S RS++R R SR RR R+ Sbjct: 1820 SSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSH---RSQTRSRSRSRRRRRSSRS 1876 Query: 64 NRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQ 123 + RGR R V + RSP+ RS+SR KR+ SS+ Sbjct: 1877 RS--------KSRGR---------------RSVSKEKRKRSPKH-RSKSRERKRKRSSSR 1912 Query: 124 ----------RSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRR--GSQEKQTKKAEG 171 R+ SR RS+ SR RS S +S SP + R + + + Sbjct: 1913 DNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSR 1972 Query: 172 EPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSP-RSPHSPS 230 P S S+ P PS + S I P +P R S S Sbjct: 1973 TPSRRSRTPSRRSRTPSRR-SRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRS 2031 Query: 231 PIATPPSQSSSCSDAP 246 PI S+SS +P Sbjct: 2032 PIRRKRSRSSERGRSP 2047 Score = 50.1 bits (118), Expect = 8e-06 Identities = 64/235 (27%), Positives = 89/235 (37%), Gaps = 29/235 (12%) Query: 102 SRSPRRGRSRSRSPKRRSVS----------------SQRSRSRSRRSYRSSRS-PRSSSS 144 SRS R S +S KR S S RSRSRSRR RSSRS +S Sbjct: 1824 SRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGR 1883 Query: 145 RSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNK 204 RS S + K R ++ +K ++++S+ + + H PS + Sbjct: 1884 RSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSV 1943 Query: 205 SSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHS 264 S I P + S RS +PS + PS+ S T TPS+ S + Sbjct: 1944 GRRRSFSISPSRRSRTPSRRS-RTPSRRSRTPSRRS--------RTPSRRSRTPSRRSRT 1994 Query: 265 IQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRS 319 S R V S SP + P RR +++ + R RGRS Sbjct: 1995 --PSRRRRSRSVVRRRSFSISPVRLRR-SRTPLRRRFSRSPIRRKRSRSSERGRS 2046 Score = 46.2 bits (108), Expect = 1e-04 Identities = 89/423 (21%), Positives = 150/423 (35%), Gaps = 48/423 (11%) Query: 211 DIWPGLSAYDN----SPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQ 266 D +PG+S D S P + P AT S+ + A LS V+ S + + Sbjct: 1579 DTYPGVSEADAGETLSSTGPFALEPDATGTSKGIEFTTASTLSLVNKYDVDLSLTTQDTE 1638 Query: 267 HSPERSGSGSVGNGSSRYSPSQNSPIH-HIPSRRS----------PAK----TIAPQNAP 311 H S S S G+ + P IH +PS + P K T+A +P Sbjct: 1639 HDMVISTSPSGGSEADIEGPLPAKDIHLDLPSNNNLVSKDTEEPLPVKESDQTLAALLSP 1698 Query: 312 RDESRGRSSFYPDGGDQETAKTGKF-----------LKSPPLHKNLDAREKSTFREESPL 360 ++ S G P +ET F L P L K+++ E PL Sbjct: 1699 KESSGGEKEVPPP--PKETLPDSGFSANIEDINEADLVRPLLPKDMERLTSLRAGIEGPL 1756 Query: 361 RIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIK 420 + D + P +S+ + + H K+ + R D + Sbjct: 1757 LASDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNR---DKGE 1813 Query: 421 LPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHR 480 + S+ S + S H +++ +S + R S + + TR +S R Sbjct: 1814 KEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRA---RKRSSKSKSHRSQTRSRSRSRRR 1870 Query: 481 RIDISPSTLRKHTRLAGEERVFKEENQKGDK---KLRCDSADLRHDIDRRRKERSKERGD 537 R + R ++ G V KE+ ++ K K R D R+ R++ R Sbjct: 1871 R-----RSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTP 1925 Query: 538 SKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESK 597 S+ SR + SR++ + +S+ + RS + S +PS R S+ Sbjct: 1926 SRRSRSHTPSRRRRS--RSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSR 1983 Query: 598 KER 600 + R Sbjct: 1984 RSR 1986 Score = 42.7 bits (99), Expect = 0.001 Identities = 91/331 (27%), Positives = 130/331 (39%), Gaps = 53/331 (16%) Query: 1 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYS-RSRSRDRMYSRDYRR 59 +GR S S S +SR+ S RSR+ SR+ R SR RSRT S RSR+ R RR Sbjct: 1943 VGRRRSFSISPSRRSRTPS---RRSRTPSRRSRTPSR-RSRTPSRRSRTPSRRSRTPSRR 1998 Query: 60 DYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSP-RRGRSRS----RS 114 R +R + R R + R R R RR SRSP RR RSRS RS Sbjct: 1999 --RRSRSVVR--------RRSFSISPVRLRRS--RTPLRRRFSRSPIRRKRSRSSERGRS 2046 Query: 115 PKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQ 174 PKR + +++ +++ + + + P + P +EK KK+ G Sbjct: 2047 PKR---LTDLDKAQLLEIAKANAAAMCAKAGVPLPPNLKPAPPPT-IEEKVAKKSGGATI 2102 Query: 175 EESPLKSK---SQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSP 231 EE K K +E D + P S +E + + + P P P Sbjct: 2103 EELTEKCKQIAQSKEDDDVIVNKPHVSDEEEEE------------PPFYHHPFKLSEPKP 2150 Query: 232 I----------ATPP-SQSSSCSDAPMLS-TVHSAKNTPSQHSHSIQHSPERSGSGSVGN 279 I TPP SQ + + P+ S + H K S + + + N Sbjct: 2151 IFFNLNIAAAKPTPPKSQVTLTKEFPVSSGSQHRKKEADSVYGEWVPVEKNGEENKDDDN 2210 Query: 280 GSSRYSPSQNSPIHHIPSRRSPAKTIAPQNA 310 S PS+ I S R+ A+ +NA Sbjct: 2211 VFSSNLPSEPVDISTAMSERALAQKRLSENA 2241 Score = 40.8 bits (94), Expect = 0.005 Identities = 72/289 (24%), Positives = 110/289 (38%), Gaps = 36/289 (12%) Query: 111 RSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKS-PVSKRRGSQEKQTKKA 169 RSRS KR S +SR R+ S RS RSS S+S ++S S+RR + K+ Sbjct: 1823 RSRS-KRSKSSEHKSRKRTSES-RSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKS 1880 Query: 170 EGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSP 229 G + +S + + E S N+ + + P + ++P Sbjct: 1881 RGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRS 1940 Query: 230 SPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQN 289 + +S S S + T TPS+ S +P R +PS+ Sbjct: 1941 RSVGR--RRSFSISPSRRSRTPSRRSRTPSRRS----RTPSRRSR----------TPSRR 1984 Query: 290 SPIHHIPSRRSPAKTIAPQNAPRDESRGRS-SFYPDG-GDQETAKTGKFLKSPPLHKNLD 347 S PSRRS +T + + R R RS S P T +F +SP K Sbjct: 1985 S---RTPSRRS--RTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRK--- 2036 Query: 348 AREKSTFREESPLRI------KMIASDSHRPEVKLKMAPVPLDDSNRPA 390 R +S+ R SP R+ +++ A VPL + +PA Sbjct: 2037 -RSRSSERGRSPKRLTDLDKAQLLEIAKANAAAMCAKAGVPLPPNLKPA 2084 Score = 35.4 bits (80), Expect = 0.19 Identities = 68/316 (21%), Positives = 122/316 (38%), Gaps = 38/316 (12%) Query: 127 SRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEE 186 SR R P S K +K++ ++++ KK + +P EES K+KS ++ Sbjct: 87 SRKSRCVSVQTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYKRQP-EESESKTKSHDD 145 Query: 187 PKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAP 246 E D D ++ SA + ++ A+ S + SP+ + PP S S+ Sbjct: 146 GNIDLESDSFLKFD--SEPSAVALEL--PTRAFGPS-ETNESPAVVLEPPVVSMEVSEPH 200 Query: 247 MLSTVHSAKNT-----------PSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHI 295 +L T+ A T Q S+ PE S + + + ++ P+ + Sbjct: 201 ILETLKPATKTAELSVVSTSVISEQSEQSVAVMPEPSMTKILDSFAAAPVPTTTL----V 256 Query: 296 PSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKSPPLHKNLDAREKSTFR 355 P T++ + + + S P E +K L PP+ K L+ E Sbjct: 257 LKSSEPVVTMSVEYQMKSVLKSVESTSP-----EPSKI--MLVEPPVAKVLEPSETLVVS 309 Query: 356 EESPLRIKMIASDSHR---PE------VKLKMAPVPLDDSNRPASLTKDRLLASTLVHSV 406 E+P + S S PE ++L PV + +S+T+ + L L + Sbjct: 310 SETPTEVYPEPSTSTTMDFPESSAIEALRLPEQPVDVPSEIADSSMTRPQELPE-LPKTT 368 Query: 407 KKEQEFRSIFDHIKLP 422 E + S+ ++LP Sbjct: 369 ALELQESSVASAMELP 384 Score = 35.4 bits (80), Expect = 0.19 Identities = 26/144 (18%), Positives = 57/144 (39%), Gaps = 3/144 (2%) Query: 463 QKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRH 522 ++A+E S + EI ++ + +K+ E+ K ++ + R S++ + Sbjct: 1777 ERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHK- 1835 Query: 523 DIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSS 582 R+R S+ R + S+ S + + + +S + SK + + S+ Sbjct: 1836 --SRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKR 1893 Query: 583 ASPSSPSSREEKESKKEREEEFKT 606 + SRE K + + KT Sbjct: 1894 SPKHRSKSRERKRKRSSSRDNRKT 1917 Score = 35.4 bits (80), Expect = 0.19 Identities = 33/154 (21%), Positives = 58/154 (37%), Gaps = 3/154 (1%) Query: 503 KEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKS 562 K+ ++K K D + D + RSK S+ S + + K + KS Sbjct: 1797 KDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKS 1856 Query: 563 YKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKEYSGFAGVSRP 622 ++ ++ + R SS S S S SK++R+ K + +E SR Sbjct: 1857 HRSQTRSRSRSRRRRRSSRS---RSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRD 1913 Query: 623 RGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKR 656 R R R +R + T + S + ++R Sbjct: 1914 NRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRR 1947 Score = 31.2 bits (69), Expect = 3.7 Identities = 16/75 (21%), Positives = 36/75 (48%), Gaps = 2/75 (2%) Query: 502 FKEENQKGDKKLRCDSA--DLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKE 559 +K + ++G +K RC S D +I ++ ++ K+ + K ++ +K ++ P++ + Sbjct: 79 YKPDLKEGSRKSRCVSVQTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYKRQPEESES 138 Query: 560 YKSYKDDSKHKREQD 574 DD E D Sbjct: 139 KTKSHDDGNIDLESD 153 >gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] Length = 2303 Score = 79.7 bits (195), Expect = 9e-15 Identities = 69/203 (33%), Positives = 97/203 (47%), Gaps = 23/203 (11%) Query: 3 RSNSRSHSSRSKSRSQSS------SRSRSRSHSRKKRYSSRSRS-----RTYSRSRSRDR 51 +S R+ SRS++R +SS S++RSRS SR++R SSRSRS R+ S+ + + Sbjct: 1835 KSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRS 1894 Query: 52 MYSRDYRRDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSR 111 R R+ + R R R R R H RR SRS R RS Sbjct: 1895 PKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPS-----RRRRSRSVGRRRSF 1949 Query: 112 SRSPKRRS-VSSQRSRSRSRRSYRSSRSPRSSSSRSSSP--YSKSPVSKRRGSQEKQTKK 168 S SP RRS S+RSR+ SRRS SR R+ S RS +P S++P +RR + + Sbjct: 1950 SISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRS 2009 Query: 169 AEGEP----QEESPLKSKSQEEP 187 P + +PL+ + P Sbjct: 2010 FSISPVRLRRSRTPLRRRFSRSP 2032 Score = 79.0 bits (193), Expect = 2e-14 Identities = 79/227 (34%), Positives = 107/227 (47%), Gaps = 22/227 (9%) Query: 3 RSNSRSHSSRSKS-RSQSSSRSRSRSHSRKKRYSSRSRSRTY-----------SRSRSRD 50 RS +R SS+SKS RSQ+ SRSRSR R R S+SR R RS+SR+ Sbjct: 1844 RSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRE 1903 Query: 51 RMYSRDYRRDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWN---RRHSRSP-R 106 R R RD R R R R R + R G R ++ R SR+P R Sbjct: 1904 RKRKRSSSRDNRKTVRARSRTPSR-RSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSR 1962 Query: 107 RGRS---RSRSPKRRS-VSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQ 162 R R+ RSR+P RRS S+RSR+ SRRS SR RS S +S SPV RR Sbjct: 1963 RSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRT 2022 Query: 163 EKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATS 209 + + + + + S+ PK + D ++ + E K++A + Sbjct: 2023 PLRRRFSRSPIRRKRSRSSERGRSPKRLTDLDKAQLL-EIAKANAAA 2068 Score = 68.2 bits (165), Expect = 3e-11 Identities = 65/199 (32%), Positives = 91/199 (45%), Gaps = 27/199 (13%) Query: 3 RSNSRSHSSRSKSRSQSSSRSRSR-----SHSRKKRYSSRS---RSRTYSRSRSRDRMYS 54 + R S RS+S+ SS +SR S SR ++ SS+S RS+T SRSRSR R S Sbjct: 1814 KEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRS 1873 Query: 55 RDYRRDYRNNRGM---RRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSR 111 R R R + +R + R + + R + V R SR+P R RSR Sbjct: 1874 SRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTV--RARSRTPSR-RSR 1930 Query: 112 SRSPKRRSVS-------------SQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKR 158 S +P RR S S+RSR+ SRRS SR R+ S RS +P +S R Sbjct: 1931 SHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSR 1990 Query: 159 RGSQEKQTKKAEGEPQEES 177 R + +++ + S Sbjct: 1991 RSRTPSRRRRSRSVVRRRS 2009 Score = 63.2 bits (152), Expect = 9e-10 Identities = 75/256 (29%), Positives = 102/256 (39%), Gaps = 41/256 (16%) Query: 4 SNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRN 63 S+ RS S RSKS S + S S SR ++ SS+S+S RS++R R SR RR R+ Sbjct: 1820 SSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSH---RSQTRSRSRSRRRRRSSRS 1876 Query: 64 NRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQ 123 + RGR R V + RSP+ RS+SR KR+ SS+ Sbjct: 1877 RS--------KSRGR---------------RSVSKEKRKRSPKH-RSKSRERKRKRSSSR 1912 Query: 124 ----------RSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRR--GSQEKQTKKAEG 171 R+ SR RS+ SR RS S +S SP + R + + + Sbjct: 1913 DNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSR 1972 Query: 172 EPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSP-RSPHSPS 230 P S S+ P PS + S I P +P R S S Sbjct: 1973 TPSRRSRTPSRRSRTPSRR-SRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRS 2031 Query: 231 PIATPPSQSSSCSDAP 246 PI S+SS +P Sbjct: 2032 PIRRKRSRSSERGRSP 2047 Score = 50.1 bits (118), Expect = 8e-06 Identities = 64/235 (27%), Positives = 89/235 (37%), Gaps = 29/235 (12%) Query: 102 SRSPRRGRSRSRSPKRRSVS----------------SQRSRSRSRRSYRSSRS-PRSSSS 144 SRS R S +S KR S S RSRSRSRR RSSRS +S Sbjct: 1824 SRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGR 1883 Query: 145 RSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNK 204 RS S + K R ++ +K ++++S+ + + H PS + Sbjct: 1884 RSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSV 1943 Query: 205 SSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHS 264 S I P + S RS +PS + PS+ S T TPS+ S + Sbjct: 1944 GRRRSFSISPSRRSRTPSRRS-RTPSRRSRTPSRRS--------RTPSRRSRTPSRRSRT 1994 Query: 265 IQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRS 319 S R V S SP + P RR +++ + R RGRS Sbjct: 1995 --PSRRRRSRSVVRRRSFSISPVRLRR-SRTPLRRRFSRSPIRRKRSRSSERGRS 2046 Score = 46.2 bits (108), Expect = 1e-04 Identities = 89/423 (21%), Positives = 150/423 (35%), Gaps = 48/423 (11%) Query: 211 DIWPGLSAYDN----SPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQ 266 D +PG+S D S P + P AT S+ + A LS V+ S + + Sbjct: 1579 DTYPGVSEADAGETLSSTGPFALEPDATGTSKGIEFTTASTLSLVNKYDVDLSLTTQDTE 1638 Query: 267 HSPERSGSGSVGNGSSRYSPSQNSPIH-HIPSRRS----------PAK----TIAPQNAP 311 H S S S G+ + P IH +PS + P K T+A +P Sbjct: 1639 HDMVISTSPSGGSEADIEGPLPAKDIHLDLPSNNNLVSKDTEEPLPVKESDQTLAALLSP 1698 Query: 312 RDESRGRSSFYPDGGDQETAKTGKF-----------LKSPPLHKNLDAREKSTFREESPL 360 ++ S G P +ET F L P L K+++ E PL Sbjct: 1699 KESSGGEKEVPPP--PKETLPDSGFSANIEDINEADLVRPLLPKDMERLTSLRAGIEGPL 1756 Query: 361 RIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIK 420 + D + P +S+ + + H K+ + R D + Sbjct: 1757 LASDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNR---DKGE 1813 Query: 421 LPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHR 480 + S+ S + S H +++ +S + R S + + TR +S R Sbjct: 1814 KEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRA---RKRSSKSKSHRSQTRSRSRSRRR 1870 Query: 481 RIDISPSTLRKHTRLAGEERVFKEENQKGDK---KLRCDSADLRHDIDRRRKERSKERGD 537 R + R ++ G V KE+ ++ K K R D R+ R++ R Sbjct: 1871 R-----RSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTP 1925 Query: 538 SKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESK 597 S+ SR + SR++ + +S+ + RS + S +PS R S+ Sbjct: 1926 SRRSRSHTPSRRRRS--RSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSR 1983 Query: 598 KER 600 + R Sbjct: 1984 RSR 1986 Score = 42.0 bits (97), Expect = 0.002 Identities = 67/210 (31%), Positives = 92/210 (43%), Gaps = 29/210 (13%) Query: 1 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYS-RSRSRDRMYSRDYRR 59 +GR S S S +SR+ S RSR+ SR+ R SR RSRT S RSR+ R RR Sbjct: 1943 VGRRRSFSISPSRRSRTPS---RRSRTPSRRSRTPSR-RSRTPSRRSRTPSRRSRTPSRR 1998 Query: 60 DYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSP-RRGRSRS----RS 114 R +R + R R + R R R RR SRSP RR RSRS RS Sbjct: 1999 --RRSRSVVR--------RRSFSISPVRLRRS--RTPLRRRFSRSPIRRKRSRSSERGRS 2046 Query: 115 PKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQ 174 PKR + +++ +++ + + + P + P +EK KK+ G Sbjct: 2047 PKR---LTDLDKAQLLEIAKANAAAMCAKAGVPLPPNLKPAPPPT-IEEKVAKKSGGATI 2102 Query: 175 EESPLKSK---SQEEPKDTFEHDPSESIDE 201 EE K K +E D + P S +E Sbjct: 2103 EELTEKCKQIAQSKEDDDVIVNKPHVSDEE 2132 Score = 40.8 bits (94), Expect = 0.005 Identities = 72/289 (24%), Positives = 110/289 (38%), Gaps = 36/289 (12%) Query: 111 RSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKS-PVSKRRGSQEKQTKKA 169 RSRS KR S +SR R+ S RS RSS S+S ++S S+RR + K+ Sbjct: 1823 RSRS-KRSKSSEHKSRKRTSES-RSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKS 1880 Query: 170 EGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSP 229 G + +S + + E S N+ + + P + ++P Sbjct: 1881 RGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRS 1940 Query: 230 SPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQN 289 + +S S S + T TPS+ S +P R +PS+ Sbjct: 1941 RSVGR--RRSFSISPSRRSRTPSRRSRTPSRRS----RTPSRRSR----------TPSRR 1984 Query: 290 SPIHHIPSRRSPAKTIAPQNAPRDESRGRS-SFYPDG-GDQETAKTGKFLKSPPLHKNLD 347 S PSRRS +T + + R R RS S P T +F +SP K Sbjct: 1985 S---RTPSRRS--RTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRK--- 2036 Query: 348 AREKSTFREESPLRI------KMIASDSHRPEVKLKMAPVPLDDSNRPA 390 R +S+ R SP R+ +++ A VPL + +PA Sbjct: 2037 -RSRSSERGRSPKRLTDLDKAQLLEIAKANAAAMCAKAGVPLPPNLKPA 2084 Score = 35.4 bits (80), Expect = 0.19 Identities = 68/316 (21%), Positives = 122/316 (38%), Gaps = 38/316 (12%) Query: 127 SRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEE 186 SR R P S K +K++ ++++ KK + +P EES K+KS ++ Sbjct: 87 SRKSRCVSVQTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYKRQP-EESESKTKSHDD 145 Query: 187 PKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAP 246 E D D ++ SA + ++ A+ S + SP+ + PP S S+ Sbjct: 146 GNIDLESDSFLKFD--SEPSAVALEL--PTRAFGPS-ETNESPAVVLEPPVVSMEVSEPH 200 Query: 247 MLSTVHSAKNT-----------PSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHI 295 +L T+ A T Q S+ PE S + + + ++ P+ + Sbjct: 201 ILETLKPATKTAELSVVSTSVISEQSEQSVAVMPEPSMTKILDSFAAAPVPTTTL----V 256 Query: 296 PSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKSPPLHKNLDAREKSTFR 355 P T++ + + + S P E +K L PP+ K L+ E Sbjct: 257 LKSSEPVVTMSVEYQMKSVLKSVESTSP-----EPSKI--MLVEPPVAKVLEPSETLVVS 309 Query: 356 EESPLRIKMIASDSHR---PE------VKLKMAPVPLDDSNRPASLTKDRLLASTLVHSV 406 E+P + S S PE ++L PV + +S+T+ + L L + Sbjct: 310 SETPTEVYPEPSTSTTMDFPESSAIEALRLPEQPVDVPSEIADSSMTRPQELPE-LPKTT 368 Query: 407 KKEQEFRSIFDHIKLP 422 E + S+ ++LP Sbjct: 369 ALELQESSVASAMELP 384 Score = 35.4 bits (80), Expect = 0.19 Identities = 26/144 (18%), Positives = 57/144 (39%), Gaps = 3/144 (2%) Query: 463 QKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRH 522 ++A+E S + EI ++ + +K+ E+ K ++ + R S++ + Sbjct: 1777 ERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHK- 1835 Query: 523 DIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSS 582 R+R S+ R + S+ S + + + +S + SK + + S+ Sbjct: 1836 --SRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKR 1893 Query: 583 ASPSSPSSREEKESKKEREEEFKT 606 + SRE K + + KT Sbjct: 1894 SPKHRSKSRERKRKRSSSRDNRKT 1917 Score = 35.4 bits (80), Expect = 0.19 Identities = 33/154 (21%), Positives = 58/154 (37%), Gaps = 3/154 (1%) Query: 503 KEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKS 562 K+ ++K K D + D + RSK S+ S + + K + KS Sbjct: 1797 KDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKS 1856 Query: 563 YKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKEYSGFAGVSRP 622 ++ ++ + R SS S S S SK++R+ K + +E SR Sbjct: 1857 HRSQTRSRSRSRRRRRSSRS---RSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRD 1913 Query: 623 RGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKR 656 R R R +R + T + S + ++R Sbjct: 1914 NRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRR 1947 Score = 31.2 bits (69), Expect = 3.7 Identities = 16/75 (21%), Positives = 36/75 (48%), Gaps = 2/75 (2%) Query: 502 FKEENQKGDKKLRCDSA--DLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKE 559 +K + ++G +K RC S D +I ++ ++ K+ + K ++ +K ++ P++ + Sbjct: 79 YKPDLKEGSRKSRCVSVQTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYKRQPEESES 138 Query: 560 YKSYKDDSKHKREQD 574 DD E D Sbjct: 139 KTKSHDDGNIDLESD 153 >gi|15055543 splicing factor, arginine/serine-rich 2B [Homo sapiens] Length = 282 Score = 79.3 bits (194), Expect = 1e-14 Identities = 70/183 (38%), Positives = 83/183 (45%), Gaps = 28/183 (15%) Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRT-YSRSRSRDRMYSRDYRRDY 61 RS S RS+SR S SRSRSRS R RYS SR+ YSRSR YSR R+ Sbjct: 124 RSRSPRRRHRSRSRGPSCSRSRSRSRYRGSRYSRSPYSRSPYSRSRYSRSPYSRSRYRES 183 Query: 62 RNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSR--SPRRGRSRSRSPKRRS 119 R GG Y GY N R+SR S R S RS Sbjct: 184 RY--------------------GGSHYSSSGYS---NSRYSRYHSSRSHSKSGSSTSSRS 220 Query: 120 VSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSP-VSKRRGSQEKQTKKAEGEPQEESP 178 S+ +S S +RRS SS S S SRSSS P VSKR+ ++K+ P+EE Sbjct: 221 ASTSKS-SSARRSKSSSVSRSRSRSRSSSMTRSPPRVSKRKSKSRSRSKRPPKSPEEEGQ 279 Query: 179 LKS 181 + S Sbjct: 280 MSS 282 Score = 60.1 bits (144), Expect = 7e-09 Identities = 70/204 (34%), Positives = 88/204 (43%), Gaps = 29/204 (14%) Query: 74 RGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRG-RSRSRSPKRRSVSSQRSRSRSRRS 132 RGR RG GG GR R R SRSPRR RSRSR P S RSRSRSR Sbjct: 106 RGRSRG---GGYGRRSRS------YGRRSRSPRRRHRSRSRGP-----SCSRSRSRSR-- 149 Query: 133 YRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFE 192 YR SR RS SRS PYS+S S+ S+ + + G S S S+ Sbjct: 150 YRGSRYSRSPYSRS--PYSRSRYSRSPYSRSRYRESRYGGSHYSSSGYSNSR-------- 199 Query: 193 HDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVH 252 + S +KS +++ S ++ RS S + S+SSS + +P V Sbjct: 200 YSRYHSSRSHSKSGSSTSSRSASTSKSSSARRSKSSSVSRSRSRSRSSSMTRSP--PRVS 257 Query: 253 SAKNTPSQHSHSIQHSPERSGSGS 276 K+ S SPE G S Sbjct: 258 KRKSKSRSRSKRPPKSPEEEGQMS 281 Score = 40.0 bits (92), Expect = 0.008 Identities = 60/222 (27%), Positives = 83/222 (37%), Gaps = 57/222 (25%) Query: 100 RHSRSPRRGRSRSRSPKRRSVS-SQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKR 158 R + RGRSR RRS S +RSRS RR SR P S SRS S Y Sbjct: 99 RSRQGEPRGRSRGGGYGRRSRSYGRRSRSPRRRHRSRSRGPSCSRSRSRSRY-------- 150 Query: 159 RGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSA 218 RGS+ ++ P SP S Sbjct: 151 RGSRYSRS------PYSRSPYSR-----------------------------------SR 169 Query: 219 YDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVG 278 Y RSP+S S S S + ++ +S ++ HS S + RS S S Sbjct: 170 YS---RSPYSRSRYRESRYGGSHYSSSGYSNSRYSRYHSSRSHSKSGSSTSSRSASTSKS 226 Query: 279 NGSSRYSPSQNSPIHHIPSR-RSPAKTIAPQNAPRDESRGRS 319 + + R S++S + SR RS + T +P + +S+ RS Sbjct: 227 SSARR---SKSSSVSRSRSRSRSSSMTRSPPRVSKRKSKSRS 265 Score = 30.0 bits (66), Expect = 8.2 Identities = 37/142 (26%), Positives = 49/142 (34%), Gaps = 16/142 (11%) Query: 462 YQKATEEHSTRQKSPEI-HRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADL 520 Y + + + R +SP HR PS R +R R + + S Sbjct: 114 YGRRSRSYGRRSRSPRRRHRSRSRGPSCSRSRSR--SRYRGSRYSRSPYSRSPYSRSRYS 171 Query: 521 RHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKH-----KREQDH 575 R R R S+ G S S SR Y Y S + SK R Sbjct: 172 RSPYSRSRYRESRYGGSHYSSSGYSNSR--------YSRYHSSRSHSKSGSSTSSRSAST 223 Query: 576 SRSSSSSASPSSPSSREEKESK 597 S+SSS+ S SS SR S+ Sbjct: 224 SKSSSARRSKSSSVSRSRSRSR 245 >gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapiens] Length = 1031 Score = 79.0 bits (193), Expect = 2e-14 Identities = 72/204 (35%), Positives = 89/204 (43%), Gaps = 42/204 (20%) Query: 1 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD 60 MGR SR + RS SR +S SRSRSRS S K+ S R R SRSR RDR R RD Sbjct: 1 MGRE-SRHYRKRSASRGRSGSRSRSRSPSDKR--SKRGDDRR-SRSRDRDRRRERSRSRD 56 Query: 61 YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 120 R +R R R R R R R R RSRS RR Sbjct: 57 KRRSRSRDRKRLRRSRSR-----------------------ERDRSRERRRSRSRDRR-- 91 Query: 121 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK 180 RSRSR RR SRSSSP +KS ++ R +++T E +++ Sbjct: 92 -RSRSRSRGRR------------SRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKKDKD 138 Query: 181 SKSQEEPKDTFEHDPSESIDEFNK 204 K E+ KD D ++ +E K Sbjct: 139 DKEDEKEKDAGNFDQNKLEEEMRK 162 Score = 61.2 bits (147), Expect = 3e-09 Identities = 58/205 (28%), Positives = 81/205 (39%), Gaps = 27/205 (13%) Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYR 62 RS SR R + R +S SR + RS SR ++ RSRSR RSR R R SRD RR Sbjct: 39 RSRSRD---RDRRRERSRSRDKRRSRSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRS 95 Query: 63 NNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSS 122 +RG R G + NR S+ G S+ K+ Sbjct: 96 RSRGRRSRSSSPGNKS---------------KKTENRSRSKEKTDGGESSKEKKKDKDDK 140 Query: 123 QRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQ---EESPL 179 + + + ++ ++ R K V K R Q K+ + GE + EE Sbjct: 141 EDEKEKDAGNFDQNKLEEEMRKR------KERVEKWREEQRKKAMENIGELKKEIEEMKQ 194 Query: 180 KSKSQEEPKDTFEHDPSESIDEFNK 204 K E D E DP+E+ E N+ Sbjct: 195 GKKWSLEDDDDDEDDPAEAEKEGNE 219 Score = 55.5 bits (132), Expect = 2e-07 Identities = 56/208 (26%), Positives = 85/208 (40%), Gaps = 28/208 (13%) Query: 541 SRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKER 600 SR SGSR + ++P D K K D R++D R S S SR+ K ++ R Sbjct: 14 SRGRSGSRSRSRSPSD-KRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSR 72 Query: 601 EEEFKTHHEMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEE 660 E E + SR R R R R R+RG + +++ N S T + +E Sbjct: 73 SRERDRSRERRR-------SRSRD---RRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKE 122 Query: 661 EWDPEYTPKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSS-PKWTHDKY 719 + D + K KK D+DD D ++ + G F + + +K KW Sbjct: 123 KTDGGESSKEKK----KDKDDKED---EKEKDAGNFDQNKLEEEMRKRKERVEKWRE--- 172 Query: 720 QGDGIVEDEEETMENNEEKKDRRKEEKE 747 E ++ MEN E K +E K+ Sbjct: 173 ------EQRKKAMENIGELKKEIEEMKQ 194 Score = 47.0 bits (110), Expect = 6e-05 Identities = 40/160 (25%), Positives = 72/160 (45%), Gaps = 13/160 (8%) Query: 458 RFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDK---KLR 514 R S +++ R +S + RR + S S ++ +R +R+ + +++ D+ + R Sbjct: 25 RSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRERDRSRERRR 84 Query: 515 CDSADLRHDIDRRRKERSKERGDSKGSRESSG-SRKQEKTP--KDYKEYKSYKDDSKHKR 571 S D R R R RS+ S+++ SR +EKT + KE K KDD + ++ Sbjct: 85 SRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKKDKDDKEDEK 144 Query: 572 EQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEMK 611 E+D + EE +KER E+++ K Sbjct: 145 EKDAGNFDQNKL-------EEEMRKRKERVEKWREEQRKK 177 Score = 37.7 bits (86), Expect = 0.039 Identities = 27/115 (23%), Positives = 45/115 (39%), Gaps = 2/115 (1%) Query: 490 RKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDR-RRKERSKERGDSKGSRESSGSR 548 RK + G DK+ + DR RR+ERS+ R D + SR R Sbjct: 9 RKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSR-DKRRSRSRDRKR 67 Query: 549 KQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEE 603 + ++ + + R + SRS + SSP ++ +K + R +E Sbjct: 68 LRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKE 122 >gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain containing B [Homo sapiens] Length = 546 Score = 76.3 bits (186), Expect = 1e-13 Identities = 65/205 (31%), Positives = 94/205 (45%), Gaps = 24/205 (11%) Query: 12 RSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNNRGMRRPY 71 RS+SR + SRSRSR +R R R + R R RDR Y ++ + R R Sbjct: 329 RSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRER 388 Query: 72 GYRGRGRG------YYQGGGGRYHRGGYRPVWN-RRHSRS-----PRRGRSRSRSPKRRS 119 R RG + + R HR R ++HSRS R RSRSR+ +RS Sbjct: 389 SKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRS 448 Query: 120 VSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPL 179 RSRS+ + S + S S+ R S+S R S EK K+ +E+S Sbjct: 449 ----RSRSKEKSSKHKNESKEKSNKR-----SRSGSQGRTDSVEKSKKREHSPSKEKSRK 499 Query: 180 KSKSQEEPKDTFEHDPSESIDEFNK 204 +S+S+E + + D S+S D+ +K Sbjct: 500 RSRSKER---SHKRDHSDSKDQSDK 521 Score = 58.5 bits (140), Expect = 2e-08 Identities = 67/311 (21%), Positives = 131/311 (42%), Gaps = 27/311 (8%) Query: 442 HVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERV 501 HV+ + +S +L+ R + + + H HR S S R+ R +R+ Sbjct: 254 HVERRRSRSPRRSLSPRRSPRRSRSRSH---------HREGHGSSSFDRELEREKERQRL 304 Query: 502 FKEENQKGDKKLRCDSADLRHDIDRRR-----KERSKERG-DSKGSRESSGSRKQEKTPK 555 +E ++ ++ R S D ++RRR + RS+ R D KG R ++++ + Sbjct: 305 EREAKEREKERRRSRSID--RGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENER 362 Query: 556 DYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKEYSG 615 + + Y + ++RE++ RS S S EEK+ K+++++ + + ++ Sbjct: 363 GRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDR-RHRDDKRDSKK 421 Query: 616 FAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYTPKSKKYFL 675 SR R + R R R+R N G + + + +K K + E + K + Sbjct: 422 EKKHSRSRSRERKHRSRSRSR------NAGKRSRSRSKEKSSKHKNESKEKSNKRSRSG- 474 Query: 676 HDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVEDEEETME-N 734 R D V+ KR ++ R R K+ + K Q D +++E Sbjct: 475 SQGRTDSVEKSKKREHSPSK-EKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQE 533 Query: 735 NEEKKDRRKEE 745 ++EK+ + K+E Sbjct: 534 SQEKQHKNKDE 544 Score = 58.5 bits (140), Expect = 2e-08 Identities = 53/182 (29%), Positives = 79/182 (43%), Gaps = 14/182 (7%) Query: 2 GRSNSRSHSS-RSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD 60 GR R + R R + RSR RS ++ R + + R R RD +++ Sbjct: 363 GRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKE 422 Query: 61 YRNNRGMRRPYGYRGRGRGYYQGGGGRY--------HRGGYRPVWNRRHSRSPRRGRSRS 112 +++R R +R R R G R H+ + N+R SRS +GR+ S Sbjct: 423 KKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKR-SRSGSQGRTDS 481 Query: 113 --RSPKR-RSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYS-KSPVSKRRGSQEKQTKK 168 +S KR S S ++SR RSR RS + S S S + + S + SQEKQ K Sbjct: 482 VEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQHKN 541 Query: 169 AE 170 + Sbjct: 542 KD 543 Score = 45.8 bits (107), Expect = 1e-04 Identities = 70/290 (24%), Positives = 99/290 (34%), Gaps = 44/290 (15%) Query: 99 RRHSRSPRRGRSRSRSPKR-RSVSSQR--------------------------SRSRSRR 131 RR SRSPRR S RSP+R RS S R R + RR Sbjct: 257 RRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKERR 316 Query: 132 SYRS---------SRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGE----PQEESP 178 RS SRS SRS S K R +EK+ ++ +E Sbjct: 317 RSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGN 376 Query: 179 LKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQ 238 + K +E ++ + S E K D D+ HS S + Sbjct: 377 EREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHR 436 Query: 239 SSSCS-DAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPS 297 S S S +A S S + + + S + S +RS SGS G S ++ H PS Sbjct: 437 SRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTD---SVEKSKKREHSPS 493 Query: 298 RRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKSPPLHKNLD 347 + K + S D D+ +++ + HKN D Sbjct: 494 KEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQHKNKD 543 Score = 43.1 bits (100), Expect = 0.001 Identities = 32/146 (21%), Positives = 59/146 (40%), Gaps = 6/146 (4%) Query: 467 EEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGD----KKLRCDSADLRH 522 E+ K HR +KH+R ER + ++ + + R +H Sbjct: 400 EKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKH 459 Query: 523 DIDRRRKERSKERGDSKGSRES-SGSRKQEKTPKDYKEYK-SYKDDSKHKREQDHSRSSS 580 + + K + R S+G +S S+K+E +P K K S + HKR+ S+ S Sbjct: 460 KNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQS 519 Query: 581 SSASPSSPSSREEKESKKEREEEFKT 606 S E++ +K+ + + +T Sbjct: 520 DKHDRRRSQSIEQESQEKQHKNKDET 545 Score = 42.7 bits (99), Expect = 0.001 Identities = 46/229 (20%), Positives = 94/229 (41%), Gaps = 31/229 (13%) Query: 520 LRHDIDRRRKERSKE-RGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRS 578 ++ +ID++ K R ++ + D K E + + + + S + + R + H R Sbjct: 225 VQKNIDQQIKTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHRE 284 Query: 579 SSSSASPSSPSSREEKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFFRIRGRGRARGV 638 S+S RE++ + ERE + + + S G+ R R R R R R+R Sbjct: 285 GHGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRRS---RSRERHRSRS- 340 Query: 639 FAGTNTGPNNSNTTFQKRPKEEEWDPEYTPKSKKYFLHD-DRDDGVDYWAKRGRGRGTFQ 697 + + +R ++ E + E ++ +D +R + + +R R R Q Sbjct: 341 --------RSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQ 392 Query: 698 RGRGRFNFKKSGSSPKWTHDKYQGDGIVEDEEETMENNEEKKDRRKEEK 746 R RG KK +++++ + ++K+D +KE+K Sbjct: 393 RSRGEVEEKKH-----------------KEDKDDRRHRDDKRDSKKEKK 424 Score = 32.3 bits (72), Expect = 1.6 Identities = 25/68 (36%), Positives = 34/68 (50%), Gaps = 2/68 (2%) Query: 118 RSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVS-KRRGSQEKQTKKAEGEPQEE 176 R V +RSRS RRS RSPR S SRS S R +EK+ ++ E E +E Sbjct: 253 RHVERRRSRS-PRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKER 311 Query: 177 SPLKSKSQ 184 + +S+ Sbjct: 312 EKERRRSR 319 >gi|42560244 peptidylprolyl isomerase G [Homo sapiens] Length = 754 Score = 76.3 bits (186), Expect = 1e-13 Identities = 69/214 (32%), Positives = 96/214 (44%), Gaps = 19/214 (8%) Query: 3 RSNSRSHSSR-SKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDY 61 R+ SRS +K + +SR+R RS SR + S R RSRT+ R RSR + Y R ++Y Sbjct: 541 RAQSRSRECDITKGKHSYNSRTRERSRSRDR--SRRVRSRTHDRDRSRSKEYHRYREQEY 598 Query: 62 RNNRGMRRPYGYR---GRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRR 118 R RG R R GR R + R R R R+ R S+S K Sbjct: 599 R-RRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKEN 657 Query: 119 SVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGS------QEKQTKKAEGE 172 S S +R S+SR S+ S + R SP+SK S + + K+ +K Sbjct: 658 SESEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSS 717 Query: 173 PQEESPLKSKSQE-----EPKDTFEHDPSESIDE 201 ++E+ KSK QE E F+H+ S DE Sbjct: 718 VEKENQ-KSKGQENDHVHEKNKKFDHESSPGTDE 750 Score = 68.2 bits (165), Expect = 3e-11 Identities = 66/214 (30%), Positives = 93/214 (43%), Gaps = 34/214 (15%) Query: 3 RSNSRSHSSRSKSRSQSSSRS----RSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYR 58 RS R H + + QS S+ RSRS + K+ S+S +S+S+ +DR R Sbjct: 488 RSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSR 547 Query: 59 -------------RDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSP 105 R +R R R R + YHR YR RR RS Sbjct: 548 ECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHR--YREQEYRRRGRSR 605 Query: 106 RR------GRSRSRSPKRR---SVSSQR--SRSRSRRSYRSSRSPRSSSSRSSSPYSKSP 154 R GRSRS+ +RR S SS+R S+SR++ YR+ S +SS + +S K Sbjct: 606 SRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQES-KSSHRKENSESEKRM 664 Query: 155 VSKRR---GSQEKQTKKAEGEPQEESPLKSKSQE 185 SK R S + KKA+ + S +K SQ+ Sbjct: 665 YSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQD 698 Score = 65.1 bits (157), Expect = 2e-10 Identities = 65/211 (30%), Positives = 90/211 (42%), Gaps = 40/211 (18%) Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKR-YSSRSRSRTYSRSRSRDRMYSRDYRRDY 61 +SN HS + ++ SRSR ++ K Y+SR+R R+ SR RSR R+ SR + RD Sbjct: 526 KSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSR-RVRSRTHDRD- 583 Query: 62 RNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVS 121 R R + Y+ RY YR RRGRSRSR R Sbjct: 584 ------------RSRSKEYH-----RYREQEYR-----------RRGRSRSRE---RRTP 612 Query: 122 SQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQT-KKAEGEPQEESPLK 180 RSRS+ RR R R RSS S +K K R + K + +K E ++ K Sbjct: 613 PGRSRSKDRR--RRRRDSRSSEREESQSRNK---DKYRNQESKSSHRKENSESEKRMYSK 667 Query: 181 SKSQEEPKDTFEHDPSESIDEFNKSSATSGD 211 S+ ++ E F+K +S D Sbjct: 668 SRDHNSSNNSREKKADRDQSPFSKIKQSSQD 698 Score = 63.9 bits (154), Expect = 5e-10 Identities = 107/510 (20%), Positives = 202/510 (39%), Gaps = 58/510 (11%) Query: 115 PKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQ 174 PK + ++ R +S S SS S SSS S S S S + E+++KK + + + Sbjct: 179 PKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQS---SSDSSDSESATEEKSKKRKKKHR 235 Query: 175 EESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIAT 234 + S K +++ K + + SES E N + + P + P P + + Sbjct: 236 KNSRKHKKEKKKRKKSKKSASSESEAE-NLEAQPQSTVRP-----EEIPPIPENRFLMRK 289 Query: 235 PPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHS--PERSGSGSVGNGSSRYSPSQNSPI 292 P ++ N P+ S Q RSG G G RY Sbjct: 290 SPPKADEKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRY-------- 341 Query: 293 HHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKF-LKSPPLHKNLDAREK 351 R+P+++ R R R S P QE + + + S D E Sbjct: 342 ------RTPSRS-------RSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSEL 388 Query: 352 STFRE--ESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKE 409 + +E SP+R+K HR + +P ++ + K + + +K+ Sbjct: 389 NEIKENQRSPVRVKERKITDHR---NVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKD 445 Query: 410 QEFRS-IFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTL-NERFTSYQKATE 467 ++++ + K SKS +S + S + +E+ +S + +E +K ++ Sbjct: 446 DKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSD 505 Query: 468 ---EHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLR-CDSADLRHD 523 + R +S E ++++ S S H++ KE++++ + R CD +H Sbjct: 506 SKGKDQERSRSKEKSKQLE-SKSNEHDHSK-------SKEKDRRAQSRSRECDITKGKHS 557 Query: 524 IDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRS--SSS 581 + R +ERS+ R S+ R + R + ++ KEY Y++ +R + SR + Sbjct: 558 YNSRTRERSRSRDRSRRVRSRTHDRDRSRS----KEYHRYREQEYRRRGRSRSRERRTPP 613 Query: 582 SASPSSPSSREEKESKKEREEEFKTHHEMK 611 S S R ++S+ EE ++ ++ K Sbjct: 614 GRSRSKDRRRRRRDSRSSEREESQSRNKDK 643 Score = 57.8 bits (138), Expect = 4e-08 Identities = 50/215 (23%), Positives = 89/215 (41%), Gaps = 25/215 (11%) Query: 5 NSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNN 64 N ++SKSRS+S +S+S+ K + R R+ S+ R + + ++ + D + Sbjct: 450 NKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGK 509 Query: 65 RGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRR-----------------HSRSPRR 107 R R + + H +RR +SR+ R Sbjct: 510 DQERS----RSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRER 565 Query: 108 GRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTK 167 RSR RS + RS + R RSRS+ +R RS S ++P + R ++ + Sbjct: 566 SRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRR 625 Query: 168 K-AEGEPQEESPLKSKSQ---EEPKDTFEHDPSES 198 + + +EES ++K + +E K + + SES Sbjct: 626 RDSRSSEREESQSRNKDKYRNQESKSSHRKENSES 660 Score = 55.5 bits (132), Expect = 2e-07 Identities = 115/619 (18%), Positives = 225/619 (36%), Gaps = 85/619 (13%) Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYR 62 R S S SS S S S SSS S+S S S ++ +S+ + + + R SR ++++ + Sbjct: 190 RHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSK---KRKKKHRKNSRKHKKEKK 246 Query: 63 NNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSS 122 + ++ P+ P +SP + Sbjct: 247 KRKKSKKSASSESEAENLEAQPQSTVRPEEIPPI--------PENRFLMRKSPPKADEKE 298 Query: 123 QRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRG---SQEKQTKKAEGEPQEESPL 179 +++R R R R +P + P S +R ++ + K G + +P Sbjct: 299 RKNRERERE-------------RECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPS 345 Query: 180 KSKSQEEPKDTFEHDPS--ESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPS 237 +S+S++ + + E P + + + +SG+ W + + + SP+ Sbjct: 346 RSRSRDRFRRS-ETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRV--- 401 Query: 238 QSSSCSDAPMLSTVHSAKNTPSQ----HSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIH 293 + +D +S + KN + H + + R S ++ S Sbjct: 402 KERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSR 461 Query: 294 HIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKSPPLHKNLDAREKST 353 +S +K ++ +E R RS G D E K + K D++ K Sbjct: 462 SKSKEKSKSKERDSKHNRNEEKRMRSR--SKGRDHENVKEKE--------KQSDSKGKDQ 511 Query: 354 FREESPLRIKMIASDSHRPE-VKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEF 412 R S + K + S S+ + K K +R +TK + ++ + ++ Sbjct: 512 ERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRD- 570 Query: 413 RSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTR 472 RS + +S S+ + H +EQ ++ R S + R Sbjct: 571 RSRRVRSRTHDRDRSRSKEY--------HRYREQEYR-------RRGRSRSRERRTPPGR 615 Query: 473 QKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERS 532 +S + RR S S+ R+ ++ +++ +E++ +K +S ++R +S Sbjct: 616 SRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSES-------EKRMYSKS 668 Query: 533 KERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSRE 592 ++ S SRE +K +D + K S QD+ SS + R Sbjct: 669 RDHNSSNNSRE-------KKADRDQSPFSKIKQSS-----QDNELKSSMLKNKEDEKIRS 716 Query: 593 --EKESKKEREEEFKTHHE 609 EKE++K + +E HE Sbjct: 717 SVEKENQKSKGQENDHVHE 735 Score = 50.8 bits (120), Expect = 4e-06 Identities = 118/603 (19%), Positives = 217/603 (35%), Gaps = 116/603 (19%) Query: 163 EKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNS 222 E Q A +P E + S + PK + + + + SS++S D Sbjct: 155 ENQKTDAASKPFAEVRILSCGELIPKSKVKKEEKKRHKSSSSSSSSSSD----------- 203 Query: 223 PRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSS 282 S ++ SS SD+ + S K +S +H E+ +S Sbjct: 204 -------SDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSAS 256 Query: 283 RYSPSQNSPIHHIPSRRSPAKTIAPQNAPR-DESRGRSSFYPDGGDQETAKTGKFLKSPP 341 S ++N P T+ P+ P E+R P D++ K Sbjct: 257 SESEAENL-------EAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKN-------- 301 Query: 342 LHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLAST 401 RE+ RE +P +++PAS + RLL + Sbjct: 302 -------RERERERECNP-------------------------PNSQPASYQR-RLLVTR 328 Query: 402 LVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKE-QYFKSAAMTLNERFT 460 +K R + P S+S S + + H +E Q + ++ ER+ Sbjct: 329 SGRKIKGRGPRR-----YRTP--SRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWI 381 Query: 461 SYQKAT-EEHSTRQKSPEIHRRIDISPSTLRKHTRLA-GEERVFKEENQKGDKKLRCDSA 518 K+ E Q+SP + + + H ++ R ++E + D K Sbjct: 382 KGDKSELNEIKENQRSP-----VRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKER 436 Query: 519 DLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRS 578 D+R + ++ K ++K + K ++ S S+ +EK+ KS + DSKH R ++ Sbjct: 437 DIRRNSEKDDKYKNKVK---KRAKSKSRSKSKEKS-------KSKERDSKHNRNEEKRMR 486 Query: 579 SSSSASPSSPSSREEKES-----KKEREEEFKTHHEMKEYSGFAGVSRPRGTFFRIRGRG 633 S S +EK+S +ER + +++ S S+ + R + R Sbjct: 487 SRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRS 546 Query: 634 RARGVFAGTNTGPNNSNTTFQKRPKE------EEWDPEYTPKSKKYFLHDDRDDGVDYWA 687 R + G ++ NS T + R ++ +SK+Y + +++ + Sbjct: 547 RECDITKGKHS--YNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQE-----YR 599 Query: 688 KRGRGRGTFQR---GRGRFNFKKSGSSPKWTHDKYQGDGIVEDEEETMENNEEKKDRRKE 744 +RGR R +R GR R ++ + ++ + +D+ N E K RKE Sbjct: 600 RRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDK---YRNQESKSSHRKE 656 Query: 745 EKE 747 E Sbjct: 657 NSE 659 Score = 49.3 bits (116), Expect = 1e-05 Identities = 57/270 (21%), Positives = 106/270 (39%), Gaps = 37/270 (13%) Query: 495 LAGEERVFKEENQKGD---------KKLRCDSADLRHDIDRRRKERSKERGDSKGSRESS 545 ++G+E V + ENQK D + L C + + + K+R K S S S Sbjct: 145 ISGQEVVREIENQKTDAASKPFAEVRILSCGELIPKSKVKKEEKKRHKSSSSSSSSSSDS 204 Query: 546 GSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFK 605 S ++ D + +S ++ KR++ H + +SR+ K+ KK+R++ K Sbjct: 205 DSSSDSQSSSDSSDSESATEEKSKKRKKKHRK-----------NSRKHKKEKKKRKKSKK 253 Query: 606 THHEMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWD-- 663 + E ++P+ T F + P + R +E E + Sbjct: 254 SASSESEAENLE--AQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNRERERERECN 311 Query: 664 -PEYTPKSKKYFLHDDRDDGVDYWAKRGRGRG-----TFQRGRGRFNFKKSGSSPKWTHD 717 P P S + L R ++ +GRG T R R R F++S + P W + Sbjct: 312 PPNSQPASYQRRLLVTRS------GRKIKGRGPRRYRTPSRSRSRDRFRRSETPPHWRQE 365 Query: 718 KYQGDGI-VEDEEETMENNEEKKDRRKEEK 746 + + V E ++ ++ + + KE + Sbjct: 366 MQRAQRMRVSSGERWIKGDKSELNEIKENQ 395 Score = 33.9 bits (76), Expect = 0.57 Identities = 22/64 (34%), Positives = 31/64 (48%), Gaps = 2/64 (3%) Query: 2 GRSNSRSHSSRSK-SRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD 60 GRS S+ R + SRS S+SR+ + + S+S R S S RMYS+ + Sbjct: 614 GRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRK-ENSESEKRMYSKSRDHN 672 Query: 61 YRNN 64 NN Sbjct: 673 SSNN 676 >gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] Length = 1301 Score = 75.9 bits (185), Expect = 1e-13 Identities = 111/492 (22%), Positives = 169/492 (34%), Gaps = 21/492 (4%) Query: 110 SRSRSPKRRSVSSQRS-RSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKK 168 S S+S S SS S S S S SS S SS S SS S S S S + Sbjct: 636 SDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSS--SDSSNSSDSSDSS 693 Query: 169 AEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHS 228 E S S + D+ + S S D + +S+ S D + D+S S S Sbjct: 694 DSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSS 753 Query: 229 PSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQ 288 S ++ S SS SD+ S + N+ + S S + S + SS S S Sbjct: 754 DSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSS 813 Query: 289 NSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKSPPLHKNLDA 348 +S + + + ++ SS DG D +++ S + D+ Sbjct: 814 DSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDS 873 Query: 349 REKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKK 408 S + S +SDS D SN S + D +S S Sbjct: 874 SNSSDSSDSSDSNESSNSSDSS-------------DSSNSSDSDSSDSSNSSDSSDSSNS 920 Query: 409 --EQEFRSIFDHIKLPQASKS--TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQK 464 E + D+ +S S +S+S S + + S + N +S Sbjct: 921 SDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSS 980 Query: 465 ATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDI 524 + + S S + D S S+ + + + + + D DS+D Sbjct: 981 NSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSS 1040 Query: 525 DRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSAS 584 D S + DS S +SS S D + D S+ D S SS SS S Sbjct: 1041 DSSDSSDSSDSSDSSNSSDSSDS-SDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDS 1099 Query: 585 PSSPSSREEKES 596 S S + +S Sbjct: 1100 SDSSDSSDSSDS 1111 Score = 67.4 bits (163), Expect = 5e-11 Identities = 103/491 (20%), Positives = 165/491 (33%), Gaps = 26/491 (5%) Query: 112 SRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEG 171 S S S SS S S S SS S S SS SS S S S + K++ Sbjct: 567 SDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDS 626 Query: 172 EPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSP 231 E S S+ + D+ D S++ D + S++++ + D+S S S S Sbjct: 627 SKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSS-----DSSDSSDSSDSSSSS 681 Query: 232 IATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSP 291 ++ S SS SD+ S + ++ S S + S S + SS S S NS Sbjct: 682 DSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSS 741 Query: 292 IHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKSPPLHKNLDAREK 351 S S + + ++ +S S +++ + S + D+ + Sbjct: 742 ----DSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDS 797 Query: 352 STFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQE 411 S + S +SDS + DS+ +S + D +S + Sbjct: 798 SNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSS-DSSNSSDSSDSSDSSDGSDSDSS 856 Query: 412 FRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHST 471 RS D +S S+ S S + NE S + +S+ Sbjct: 857 NRS--DSSNSSDSSDSSDSS-------------NSSDSSDSSDSNESSNSSDSSDSSNSS 901 Query: 472 RQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKER 531 S + D S S+ + + + + DS+D + D Sbjct: 902 DSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSD 961 Query: 532 SKERGDSKGSRESSGSRKQEKT-PKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSS 590 S DS S S S + D + D S D S SS SS S +S S Sbjct: 962 SSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDS 1021 Query: 591 REEKESKKERE 601 +S + Sbjct: 1022 SNSSDSSNSSD 1032 Score = 66.6 bits (161), Expect = 8e-11 Identities = 125/603 (20%), Positives = 199/603 (33%), Gaps = 15/603 (2%) Query: 5 NSRSHSSRSKSRSQSSSRSRSRSHSRKKRYS----SRSRSRTYSRSRSRDRMYSRDYRRD 60 N +S S + KS S S S S + S S S S S + S S D S D Sbjct: 537 NDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSS 596 Query: 61 YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 120 +N + + S+S + S S Sbjct: 597 DSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDS 656 Query: 121 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK 180 S + S S S SS S SSSS SS S S S + + + ++ + S Sbjct: 657 SDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSS 716 Query: 181 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS 240 S D+ + S+S D N S S D ++ D+S S S S ++ S SS Sbjct: 717 DSSNSNSSDSDSSNSSDSSDSSNSSD--SSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSS 774 Query: 241 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS 300 SD+ S + + N+ S S S S + S S + S S S NS S S Sbjct: 775 DSSDSSNSSDSNDSSNS-SDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSS 833 Query: 301 PAKTIAPQNAPRDESRGRSSFYPDGGDQ----ETAKTGKFLKSPPLHKNLDAREKSTFRE 356 + + + D S G S + D +++ + S + D+ E S + Sbjct: 834 DSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSD 893 Query: 357 ESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIF 416 S + S DS+ ++ + + + + S + S Sbjct: 894 SSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNS 953 Query: 417 DHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSP 476 S ++S+S + ++ + + +S + + S S Sbjct: 954 SDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1013 Query: 477 EIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSA---DLRHDIDRRRKERSK 533 + D S S+ ++ + + + + D DS+ D D S Sbjct: 1014 DSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 1073 Query: 534 ERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREE 593 + DS S ESS S D + D S D S SS SS S S S + Sbjct: 1074 DSSDSSDSSESSDS-SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS 1132 Query: 594 KES 596 +S Sbjct: 1133 SDS 1135 Score = 63.5 bits (153), Expect = 7e-10 Identities = 137/617 (22%), Positives = 191/617 (30%), Gaps = 63/617 (10%) Query: 4 SNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRN 63 S S S SS S S+S SS + S S S + S + S S D S D N Sbjct: 627 SKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSS-SSDSSN 685 Query: 64 NRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQ 123 + N S S S S S SS Sbjct: 686 SSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSD 745 Query: 124 RS-RSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSK 182 S S S S SS S SS S SS S S S + ++ S S Sbjct: 746 SSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSN 805 Query: 183 SQE--EPKDTFEHDPSESIDEFNKS----------SATSGDIWPGLSAYDNSPRSPHSPS 230 S + + D+ + D S S D N S S+ S D G S D+S RS S S Sbjct: 806 SSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDG-SDSDSSNRSDSSNS 864 Query: 231 PIATPPSQSSSCSDAPMLSTVHSAKNTP--SQHSHSIQHSPERSGSGSVGNGSSRYSPSQ 288 ++ S SS+ SD+ S + + N+ S S+S S + S + SS S S Sbjct: 865 SDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSS 924 Query: 289 NSPIHHIPSRRSPAKTIAPQNAPRDESRGR-------SSFYPDGGDQETAKTGKFLKSPP 341 S S S + + + D S SS D D ++ + S Sbjct: 925 ESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSD 984 Query: 342 LHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLAST 401 + D+ + S + S +SDS D SN S S+ Sbjct: 985 SSDSSDSSDSSDSSDSSNSSDSSDSSDSS-------------DSSNSSDSSNSSDSSNSS 1031 Query: 402 LVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTS 461 + D +S S+ S + +S Sbjct: 1032 DSSDSSDSSDSSDSSDSSDSSDSSNSSDSS------------------------DSSDSS 1067 Query: 462 YQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLR 521 + + S S E D S S+ + + + + + D +S+D Sbjct: 1068 DSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1127 Query: 522 HDIDRRRKERSKERGDSKGSRESSGS--RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSS 579 D S DS S ESS S D + D S D S SS Sbjct: 1128 DSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1187 Query: 580 SSSASPSSPSSREEKES 596 SS S S S + +S Sbjct: 1188 DSSDSSDSSDSSDSSDS 1204 Score = 62.8 bits (151), Expect = 1e-09 Identities = 124/596 (20%), Positives = 195/596 (32%), Gaps = 19/596 (3%) Query: 4 SNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRN 63 SNS S S S SS S S+S S + S + S S D S D + Sbjct: 696 SNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDS 755 Query: 64 NRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQ 123 + + N S S S S + S SS Sbjct: 756 SDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDS-SDSSNSSDSSNSSDSSDSSD 814 Query: 124 RSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKK--AEGEPQEESPLKS 181 S S S S SS S SS S +SS S S S + + + +S S Sbjct: 815 SSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSS 874 Query: 182 KSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSS 241 S + + ++ S S D + S+++ D ++ D+S S S S ++ S +S+ Sbjct: 875 NSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSN 934 Query: 242 CSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSP 301 SD+ S+ S + S S S S + S S + SS S S NS S S Sbjct: 935 SSDSSN-SSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSD 993 Query: 302 AKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKSPPLHKNLDAREKSTFREESPLR 361 + + + D S S +++ + S + D+ + S + S Sbjct: 994 SSDSSDSSNSSDSSDSSDSS-DSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1052 Query: 362 IKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKL 421 +SDS + + +S + D +S S S D Sbjct: 1053 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSS-DSSDS 1111 Query: 422 PQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRR 481 +S S+ S +++ + + +S + + S S + Sbjct: 1112 SDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDS 1171 Query: 482 IDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGS 541 D S S+ + + + + + D DS+D D S + DS S Sbjct: 1172 SDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1231 Query: 542 RESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESK 597 ESS S D S D S SS SS S S + + +SK Sbjct: 1232 NESSDS-------------SDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSK 1274 Score = 52.8 bits (125), Expect = 1e-06 Identities = 51/179 (28%), Positives = 73/179 (40%), Gaps = 2/179 (1%) Query: 121 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK 180 S+ S S S SS S SS S SS S S S + ++ +S Sbjct: 1121 SNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNS 1180 Query: 181 SKSQEEPKDTFEHDPSESIDEFNKS-SATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQS 239 S S + + D S+S D + S S+ S D + D+S S S S ++ S S Sbjct: 1181 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDS 1240 Query: 240 SSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGS-VGNGSSRYSPSQNSPIHHIPS 297 S SD+ S + ++ S S S +S SG+ NGS S S+ S +H S Sbjct: 1241 SDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTS 1299 Score = 50.4 bits (119), Expect = 6e-06 Identities = 88/468 (18%), Positives = 162/468 (34%), Gaps = 15/468 (3%) Query: 135 SSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHD 194 +S S +SSSR + Y+ S SK G+ +K AE + + + + S +D Sbjct: 478 NSESDNNSSSRGDASYN-SDESKDNGNGS-DSKGAEDDDSDSTSDTNNSDSNGNGNNGND 535 Query: 195 PSESIDEFN-KSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHS 253 ++ D KS ++ D ++ D+S S S + SS SD+ S S Sbjct: 536 DNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDS 595 Query: 254 AKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRD 313 + ++ S S S + S S + S S S+ S S+ + + + ++ Sbjct: 596 SDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSE-SDSSDSDSKSDSSDSNSSDSSDNS 654 Query: 314 ESRGRSSFYPDGGDQETAKTGKFLKSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPE 373 +S S+ +++ + S + D+ + S S +SDS Sbjct: 655 DSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSS- 713 Query: 374 VKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFI 433 D S+ S + D +++ S S S +S+S Sbjct: 714 ----------DSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSN 763 Query: 434 QHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHT 493 S + S + N+ S + +S+ + S + ++ Sbjct: 764 SSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNS 823 Query: 494 RLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKT 553 + + + D DS+D R + S S S S+ S + + Sbjct: 824 SDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSS 883 Query: 554 PKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKERE 601 + S DS + + D S SS+SS S S +S + ES + Sbjct: 884 DSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSD 931 Score = 48.1 bits (113), Expect = 3e-05 Identities = 43/170 (25%), Positives = 67/170 (39%), Gaps = 1/170 (0%) Query: 121 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK 180 S + S S S SS S SS+S SS S+S S + ++ +S Sbjct: 1118 SDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDS 1177 Query: 181 SKSQEEPKDTFEHDPSESIDEFNKS-SATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQS 239 S S + + D S+S D + S S+ S D + D+S S S S + S S Sbjct: 1178 SNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDS 1237 Query: 240 SSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQN 289 S SD+ S + ++ + + E GNG++ S S + Sbjct: 1238 SDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDS 1287 Score = 42.7 bits (99), Expect = 0.001 Identities = 54/226 (23%), Positives = 79/226 (34%), Gaps = 2/226 (0%) Query: 110 SRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKA 169 S + S S S S S S S S S SS SS+ S S S + + + Sbjct: 1054 SSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSD-SSDSS 1112 Query: 170 EGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKS-SATSGDIWPGLSAYDNSPRSPHS 228 + +S S S + + D S S D + S S+ S D + D+S S S Sbjct: 1113 DSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSS 1172 Query: 229 PSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQ 288 S ++ S SS SD+ S + ++ S S S + SS S S Sbjct: 1173 DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSN 1232 Query: 289 NSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTG 334 S S S + + + D S S + Q + G Sbjct: 1233 ESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNG 1278 Score = 30.4 bits (67), Expect = 6.3 Identities = 29/130 (22%), Positives = 43/130 (33%), Gaps = 29/130 (22%) Query: 502 FKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGD----------------SKGSRE-- 543 F +++ +GD D ++ D + S RGD SKG+ + Sbjct: 455 FDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDD 514 Query: 544 -----------SSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSRE 592 S+G+ D + K DS D S SS SS S S SS Sbjct: 515 SDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDS 574 Query: 593 EKESKKEREE 602 S + + Sbjct: 575 NSSSDSDSSD 584 >gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo sapiens] Length = 375 Score = 73.2 bits (178), Expect = 8e-13 Identities = 60/186 (32%), Positives = 90/186 (48%), Gaps = 23/186 (12%) Query: 1 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD 60 + S + + K R S RS SRS SR++R+ SRSR R SRSRSR+R SR R+ Sbjct: 43 LNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRE 102 Query: 61 YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 120 + +R R R R R + +R +RS R RSRSR K+R Sbjct: 103 RKKSRSRSRERKRRIRSRSRSRSR-------------HRHRTRSRSRTRSRSRDRKKRIE 149 Query: 121 SSQR-SRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPL 179 +R SRS SR + SP R+++ ++ +++R ++ KK + + ++E Sbjct: 150 KPRRFSRSLSR-----TPSPPPFRGRNTAMDAQEALARRL----ERAKKLQEQREKEMVE 200 Query: 180 KSKSQE 185 K K QE Sbjct: 201 KQKQQE 206 Score = 55.1 bits (131), Expect = 2e-07 Identities = 54/176 (30%), Positives = 79/176 (44%), Gaps = 23/176 (13%) Query: 12 RSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNNRGMRRPY 71 R +S+ +SS + +S H+ K+ S + R R S DR R++ +++RG Sbjct: 13 RHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDR----HKRKERKSSRGRSHS- 67 Query: 72 GYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRR 131 R R R R HR R R SRS R +SRSRS +R+ +SRSRSR Sbjct: 68 --RSRSRE-------RRHRSRSRERKKSR-SRSRERKKSRSRSRERK-----KSRSRSRE 112 Query: 132 SYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEP 187 R RS S SR ++ R S+ + KK +P+ S S++ P Sbjct: 113 RKRRIRSRSRSRSRHR---HRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPP 165 Score = 47.0 bits (110), Expect = 6e-05 Identities = 45/168 (26%), Positives = 73/168 (43%), Gaps = 13/168 (7%) Query: 456 NERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRC 515 N++ S K E ++ + + H+R + S R H+R ER + +++ KK R Sbjct: 30 NDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRE-RKKSRS 88 Query: 516 DSADLRHDIDRRR-----KERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHK 570 S + + R R + RS+ER SR S SR + +T + +S D K + Sbjct: 89 RSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRT-RSRSRTRSRSRDRKKR 147 Query: 571 REQDHSRSSSSSASPSSPSSR------EEKESKKEREEEFKTHHEMKE 612 E+ S S S +PS P R + +E+ R E K E +E Sbjct: 148 IEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQRE 195 Score = 45.1 bits (105), Expect = 2e-04 Identities = 56/227 (24%), Positives = 86/227 (37%), Gaps = 37/227 (16%) Query: 458 RFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDS 517 R + K H ++ KS + H+ + + ++H+ G ER+ EN + Sbjct: 3 RTNFFLKQGRRHESKDKSSKKHKSEEHND---KEHSSDKGRERLNSSENGED-------- 51 Query: 518 ADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSR 577 RH +RKER RG S SR S R+ ++ K+ +S RE+ SR Sbjct: 52 ---RH----KRKERKSSRGRSH-SRSRSRERRHRSRSRERKKSRS------RSRERKKSR 97 Query: 578 SSSSSASPSSPSSREEKESKKEREEEFKTH-HEMKEYSGFAGVSRPR-------GTFFRI 629 S S S SRE K + R H H + S SR R F R Sbjct: 98 SRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRS 157 Query: 630 RGRGRARGVFAGTNTGPNNSNTTFQK----RPKEEEWDPEYTPKSKK 672 R + F G NT + ++ + +E+ + E K K+ Sbjct: 158 LSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQ 204 Score = 34.3 bits (77), Expect = 0.43 Identities = 28/104 (26%), Positives = 46/104 (44%), Gaps = 14/104 (13%) Query: 99 RRHS---RSPRRGRSRSRSPKRRSVSSQRSRSRS---------RRSYRSSRSPRSSSSRS 146 RRH +S ++ +S + K S R R S R+ +SSR S SRS Sbjct: 12 RRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRS 71 Query: 147 SS--PYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPK 188 S+S K+ S+ ++ KK+ +E +S+S+E + Sbjct: 72 RERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKR 115 Score = 30.0 bits (66), Expect = 8.2 Identities = 44/187 (23%), Positives = 71/187 (37%), Gaps = 14/187 (7%) Query: 441 HHVKEQYFKSAAMTLN--ERFTSYQKATEEHSTRQKSPEIHR---RIDISPSTLRKHTRL 495 H+ KE LN E K E S+R +S R R S S RK +R Sbjct: 29 HNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRS 88 Query: 496 AGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKE----RGDSKGSRESSGSRKQE 551 ER + KK R S + + I R + RS+ R S+ S +K+ Sbjct: 89 RSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRI 148 Query: 552 KTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREE-KESKKEREEEFKTHHEM 610 + P+ + S R R+++ A + E K+ +++RE+E + Sbjct: 149 EKPRRFSRSLSRTPSPPPFR----GRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQ 204 Query: 611 KEYSGFA 617 +E + A Sbjct: 205 QEIAAAA 211 >gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo sapiens] Length = 434 Score = 73.2 bits (178), Expect = 8e-13 Identities = 60/186 (32%), Positives = 90/186 (48%), Gaps = 23/186 (12%) Query: 1 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD 60 + S + + K R S RS SRS SR++R+ SRSR R SRSRSR+R SR R+ Sbjct: 102 LNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRE 161 Query: 61 YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 120 + +R R R R R + +R +RS R RSRSR K+R Sbjct: 162 RKKSRSRSRERKRRIRSRSRSRSR-------------HRHRTRSRSRTRSRSRDRKKRIE 208 Query: 121 SSQR-SRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPL 179 +R SRS SR + SP R+++ ++ +++R ++ KK + + ++E Sbjct: 209 KPRRFSRSLSR-----TPSPPPFRGRNTAMDAQEALARRL----ERAKKLQEQREKEMVE 259 Query: 180 KSKSQE 185 K K QE Sbjct: 260 KQKQQE 265 Score = 67.0 bits (162), Expect = 6e-11 Identities = 57/186 (30%), Positives = 86/186 (46%), Gaps = 15/186 (8%) Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYR 62 +S++ RS+SRS+ R S+ S KK S + +S + R+R+ S + D R Sbjct: 53 KSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGED-R 111 Query: 63 NNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKR-RSVS 121 + R R+ RGR + R R +R SR ++ RSRSR K+ RS S Sbjct: 112 HKRKERK----SSRGRS--------HSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRS 159 Query: 122 SQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKS 181 +R +SRSR R R S SRS + S+ R S+ + KK +P+ S S Sbjct: 160 RERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTR-SRSRDRKKRIEKPRRFSRSLS 218 Query: 182 KSQEEP 187 ++ P Sbjct: 219 RTPSPP 224 Score = 66.2 bits (160), Expect = 1e-10 Identities = 59/188 (31%), Positives = 92/188 (48%), Gaps = 17/188 (9%) Query: 6 SRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNNR 65 S+ H SRS+SRS+ R +S + +++ SRSRS+ R S+D+ S+ ++ + N++ Sbjct: 36 SKHHYSRSRSRSRERKR---KSDNEGRKHRSRSRSKEGRRHESKDKS-SKKHKSEEHNDK 91 Query: 66 GMRRPYGYRGRGR-GYYQGGGGRYHRGGYRPVWNRRHSRS---PRRGRSRSRSPKRRSVS 121 +GR R + G R+ R + R HSRS RR RSRSR K+ Sbjct: 92 EHSSD---KGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKK---- 144 Query: 122 SQRSRSRSRRSYRS-SRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK 180 RSRSR R+ RS SR + S SRS + R S+ + ++ + S + Sbjct: 145 -SRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDR 203 Query: 181 SKSQEEPK 188 K E+P+ Sbjct: 204 KKRIEKPR 211 Score = 48.9 bits (115), Expect = 2e-05 Identities = 46/177 (25%), Positives = 73/177 (41%), Gaps = 8/177 (4%) Query: 465 ATEEHSTRQKSPEIHRRIDISPSTLRKH---TRLAGEERVFKEENQKGDKKLRCDSAD-L 520 A E+ S + + + +SP + H +R ER K +N+ + R S + Sbjct: 12 APEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGR 71 Query: 521 RHDI-DRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSS 579 RH+ D+ K+ E + K SS ++ + E + + + K R + HSRS Sbjct: 72 RHESKDKSSKKHKSEEHNDK--EHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSR 129 Query: 580 SSSASPSSPSSREEKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFFRIRGRGRAR 636 S S SRE K+S+ E K+ +E SR R R R R R+R Sbjct: 130 SRERRHRS-RSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSR 185 Score = 47.4 bits (111), Expect = 5e-05 Identities = 53/258 (20%), Positives = 97/258 (37%), Gaps = 19/258 (7%) Query: 495 LAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKER---GDSKGSRESSGSRKQE 551 LA E+ + +K ++ +H R R RS+ER D++G + S SR +E Sbjct: 11 LAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRS-RSRERKRKSDNEGRKHRSRSRSKE 69 Query: 552 KTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEMK 611 + K+ S K S+ +++HS SS + + + K+ + ++H + Sbjct: 70 GRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSR 129 Query: 612 EYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYTPKSK 671 SR R R R R ++R + S + R + E +S+ Sbjct: 130 --------SRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSR 181 Query: 672 KYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRF--NFKKSGSSPKWTHDKYQGDGIVEDEE 729 H R R R R RF + ++ S P ++G D + Sbjct: 182 SRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPP-----PFRGRNTAMDAQ 236 Query: 730 ETMENNEEKKDRRKEEKE 747 E + E+ + +E++E Sbjct: 237 EALARRLERAKKLQEQRE 254 Score = 47.0 bits (110), Expect = 6e-05 Identities = 45/168 (26%), Positives = 73/168 (43%), Gaps = 13/168 (7%) Query: 456 NERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRC 515 N++ S K E ++ + + H+R + S R H+R ER + +++ KK R Sbjct: 89 NDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRE-RKKSRS 147 Query: 516 DSADLRHDIDRRR-----KERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHK 570 S + + R R + RS+ER SR S SR + +T + +S D K + Sbjct: 148 RSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRT-RSRSRTRSRSRDRKKR 206 Query: 571 REQDHSRSSSSSASPSSPSSR------EEKESKKEREEEFKTHHEMKE 612 E+ S S S +PS P R + +E+ R E K E +E Sbjct: 207 IEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQRE 254 Score = 34.7 bits (78), Expect = 0.33 Identities = 29/108 (26%), Positives = 45/108 (41%), Gaps = 9/108 (8%) Query: 104 SPRRGRSRSRS-----PKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKR 158 SP R + + +S P+ RSRSRSR R S + R S+S +R Sbjct: 17 SPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKS----DNEGRKHRSRSRSKEGRR 72 Query: 159 RGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSS 206 S++K +KK + E + S E ++ E+ + KSS Sbjct: 73 HESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSS 120 Score = 30.0 bits (66), Expect = 8.2 Identities = 44/187 (23%), Positives = 71/187 (37%), Gaps = 14/187 (7%) Query: 441 HHVKEQYFKSAAMTLN--ERFTSYQKATEEHSTRQKSPEIHR---RIDISPSTLRKHTRL 495 H+ KE LN E K E S+R +S R R S S RK +R Sbjct: 88 HNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRS 147 Query: 496 AGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKE----RGDSKGSRESSGSRKQE 551 ER + KK R S + + I R + RS+ R S+ S +K+ Sbjct: 148 RSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRI 207 Query: 552 KTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREE-KESKKEREEEFKTHHEM 610 + P+ + S R R+++ A + E K+ +++RE+E + Sbjct: 208 EKPRRFSRSLSRTPSPPPFR----GRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQ 263 Query: 611 KEYSGFA 617 +E + A Sbjct: 264 QEIAAAA 270 >gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens] Length = 344 Score = 72.8 bits (177), Expect = 1e-12 Identities = 61/177 (34%), Positives = 76/177 (42%), Gaps = 18/177 (10%) Query: 13 SKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNNRGMRRPYG 72 S RS S SRSRSRS R SRSRSR SRSRSR SR R R R G Sbjct: 186 SHRRSYSGSRSRSRSRRR-----SRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKG 240 Query: 73 YRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRS 132 + R + + R R + +S R RSRSRSPK +S+SRSR Sbjct: 241 RKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKS--RSRSRSRSPKENGKGDIKSKSRSR-- 296 Query: 133 YRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKD 189 S SRS+SP P R S + + + S +S+S+ +D Sbjct: 297 ---------SQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSSSRD 344 Score = 71.2 bits (173), Expect = 3e-12 Identities = 63/180 (35%), Positives = 86/180 (47%), Gaps = 17/180 (9%) Query: 101 HSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRG 160 + R+ R + R+ RRS S RSRSRSRR RS RS RSS SRS S SKS R Sbjct: 172 NGRNIRLIEDKPRTSHRRSYSGSRSRSRSRRRSRS-RSRRSSRSRSRS-ISKSRSRSRSR 229 Query: 161 SQEKQTKKAEGEPQEESPLKSKSQEEPKD---TFEHDPSESIDEFNKSSATSGDIWP--- 214 S+ + +++G +SKS+ +PK + H S S DE+ KS + S P Sbjct: 230 SKGRSRSRSKGRKS-----RSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKEN 284 Query: 215 ---GLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPER 271 + + S S SP+ PPS++ S S P +T S + S+ S S S R Sbjct: 285 GKGDIKSKSRSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSK-SRSRSRSSSR 343 Score = 68.6 bits (166), Expect = 2e-11 Identities = 60/153 (39%), Positives = 75/153 (49%), Gaps = 30/153 (19%) Query: 3 RSNSRSHS-SRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDY 61 RS SRS S SRS+SRS+S RSRSRS RK R S+S+ ++ S S R S+D +Y Sbjct: 213 RSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKD---EY 269 Query: 62 RNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSP------ 115 +R R + G+G + S+S R +SRS SP Sbjct: 270 EKSRSRSRSRSPKENGKGDIK-------------------SKSRSRSQSRSNSPLPVPPS 310 Query: 116 KRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSS 148 K RSVS R+ SR R SRS S SRSSS Sbjct: 311 KARSVSPPPKRATSRSRSR-SRSKSRSRSRSSS 342 Score = 50.1 bits (118), Expect = 8e-06 Identities = 54/201 (26%), Positives = 75/201 (37%), Gaps = 50/201 (24%) Query: 1 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD 60 M R+ + + R+ + R+ R+ SRSRSR+ RSRSR R SR Sbjct: 159 MKRALDKLDGTEINGRNIRLIEDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRS---- 214 Query: 61 YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 120 SRS + RSRSRS RS Sbjct: 215 ----------------------------------------RSRSISKSRSRSRS---RSK 231 Query: 121 SSQRSRSRSRRSYRSSRS-PRS--SSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEES 177 RSRS+ R+S S+S P+S S S SK K R ++ K G+ +S Sbjct: 232 GRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKS 291 Query: 178 PLKSKSQEEPKDTFEHDPSES 198 +S+SQ PS++ Sbjct: 292 KSRSRSQSRSNSPLPVPPSKA 312 Score = 38.1 bits (87), Expect = 0.030 Identities = 37/149 (24%), Positives = 51/149 (34%), Gaps = 17/149 (11%) Query: 461 SYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVF---KEENQKGDKKLRCDS 517 S ++ +R + R IS S R +R G R ++ K K + D Sbjct: 196 SRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDR 255 Query: 518 ADLRHDIDRRRKERSKERGDSKG--------------SRESSGSRKQEKTPKDYKEYKSY 563 H R + E K R S+ SR S SR P + +S Sbjct: 256 GSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSV 315 Query: 564 KDDSKHKREQDHSRSSSSSASPSSPSSRE 592 K + SRS S S S S SSR+ Sbjct: 316 SPPPKRATSRSRSRSRSKSRSRSRSSSRD 344 Score = 37.4 bits (85), Expect = 0.051 Identities = 33/125 (26%), Positives = 52/125 (41%), Gaps = 5/125 (4%) Query: 480 RRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRR-KERSKERGDS 538 R I+ P T H R R ++ + R S I + R + RS+ +G S Sbjct: 177 RLIEDKPRT--SHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRS 234 Query: 539 KGSRESSGSRKQEKT-PKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESK 597 + + SR + K+ PK + S+ S+ K E + SRS S S SP + K Sbjct: 235 RSRSKGRKSRSKSKSKPKSDRGSHSHSR-SRSKDEYEKSRSRSRSRSPKENGKGDIKSKS 293 Query: 598 KEREE 602 + R + Sbjct: 294 RSRSQ 298 Score = 36.2 bits (82), Expect = 0.11 Identities = 36/143 (25%), Positives = 56/143 (39%), Gaps = 13/143 (9%) Query: 529 KERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSP 588 K R+ R GSR S SR++ +S S R + S+S S S S S Sbjct: 182 KPRTSHRRSYSGSRSRSRSRRRS---------RSRSRRSSRSRSRSISKSRSRSRSRSKG 232 Query: 589 SSREEKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNN 648 SR + +K R + K+ + S SR + + + R R R+R + G + Sbjct: 233 RSRSRSKGRKSRSKS-KSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSR---SPKENGKGD 288 Query: 649 SNTTFQKRPKEEEWDPEYTPKSK 671 + + R + P P SK Sbjct: 289 IKSKSRSRSQSRSNSPLPVPPSK 311 >gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens] Length = 330 Score = 71.6 bits (174), Expect = 2e-12 Identities = 58/137 (42%), Positives = 67/137 (48%), Gaps = 21/137 (15%) Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYR 62 RS SRS SRS SRS S S SRSRS SR R SS S+SR+ S SR R R R R Sbjct: 203 RSKSRSSHSRSSSRSSSPSSSRSRSRSRS-RSSSSSQSRSRSSSRERSRSRGSKSRSSSR 261 Query: 63 NNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSP-------RRGRSRSRSP 115 ++RG P R R Y P NR+ SRS ++ R+RSRSP Sbjct: 262 SHRGSSSP-----RKRSYSSSSSS--------PERNRKRSRSRSSSSGDRKKRRTRSRSP 308 Query: 116 KRRSVSSQRSRSRSRRS 132 +RR SS S RS Sbjct: 309 ERRHRSSSGSSHSGSRS 325 Score = 70.1 bits (170), Expect = 7e-12 Identities = 57/155 (36%), Positives = 72/155 (46%), Gaps = 14/155 (9%) Query: 1 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRS--RTYSRSRSRDRMYSRDYR 58 + + N + ++ +S+ RSRS+S S R SSRS S + SRSRSR R S Sbjct: 180 LSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQS 239 Query: 59 RDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWN--RRHSRSPRRGRSRSRSPK 116 R ++R R R RG R HRG P S SP R R RSRS Sbjct: 240 RSRSSSR-------ERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRS 292 Query: 117 RRSVSSQRSRSRSR---RSYRSSRSPRSSSSRSSS 148 S ++ R+RSR R +RSS S SRSSS Sbjct: 293 SSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSS 327 Score = 62.8 bits (151), Expect = 1e-09 Identities = 59/182 (32%), Positives = 74/182 (40%), Gaps = 48/182 (26%) Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYR 62 +SN RS S S S+SSSRS S S SR + SRSRSR+ S S+SR R SR+ Sbjct: 197 KSNRRSRSKSRSSHSRSSSRSSSPSSSRSR---SRSRSRSSSSSQSRSRSSSRE------ 247 Query: 63 NNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSS 122 R R RG +SRS S R SS Sbjct: 248 -----------RSRSRG----------------------------SKSRSSSRSHRGSSS 268 Query: 123 QRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSK 182 R RS S S R+ + S SRSSS + R S E++ + + G S SK Sbjct: 269 PRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSSK 328 Query: 183 SQ 184 + Sbjct: 329 KK 330 Score = 52.8 bits (125), Expect = 1e-06 Identities = 36/93 (38%), Positives = 47/93 (50%), Gaps = 9/93 (9%) Query: 102 SRSPRRGRSRSRSPKRRSVSSQ---------RSRSRSRRSYRSSRSPRSSSSRSSSPYSK 152 S SP RSRSRS R S SSQ RSRSR +S SSRS R SSS YS Sbjct: 217 SSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSS 276 Query: 153 SPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQE 185 S S R + +++ + +++ +S+S E Sbjct: 277 SSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPE 309 Score = 47.8 bits (112), Expect = 4e-05 Identities = 43/187 (22%), Positives = 76/187 (40%), Gaps = 2/187 (1%) Query: 456 NERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDK-KLR 514 N + +++ E+ + + +R + P+++ K E ++E++ K KL Sbjct: 111 NVEYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLD 170 Query: 515 CDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQD 574 D + D+ + + S+E DS + + SR + ++ +S S R + Sbjct: 171 EDEDEDDADLSKYNLDASEEE-DSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRS 229 Query: 575 HSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFFRIRGRGR 634 SRSSSSS S S SSRE S+ + H S + R R R R Sbjct: 230 RSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSR 289 Query: 635 ARGVFAG 641 +R +G Sbjct: 290 SRSSSSG 296 Score = 47.4 bits (111), Expect = 5e-05 Identities = 35/87 (40%), Positives = 47/87 (54%), Gaps = 4/87 (4%) Query: 103 RSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQ 162 +S RR RS+SRS RS SS+ S S RS SRS SSSS+S S S S+ RGS+ Sbjct: 197 KSNRRSRSKSRSSHSRS-SSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSK 255 Query: 163 EKQTKKA---EGEPQEESPLKSKSQEE 186 + + ++ P++ S S S E Sbjct: 256 SRSSSRSHRGSSSPRKRSYSSSSSSPE 282 Score = 47.4 bits (111), Expect = 5e-05 Identities = 41/124 (33%), Positives = 51/124 (41%), Gaps = 1/124 (0%) Query: 87 RYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRS 146 R R R +R SRS SRSRS + RS SS S+SRSR S R R S SRS Sbjct: 200 RRSRSKSRSSHSRSSSRSSSPSSSRSRS-RSRSRSSSSSQSRSRSSSRERSRSRGSKSRS 258 Query: 147 SSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSS 206 SS + S R+ S + E + S S + K E + S Sbjct: 259 SSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGS 318 Query: 207 ATSG 210 + SG Sbjct: 319 SHSG 322 Score = 43.5 bits (101), Expect = 7e-04 Identities = 54/193 (27%), Positives = 82/193 (42%), Gaps = 22/193 (11%) Query: 145 RSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNK 204 R Y V +E + K++EGE ++E SK + D E + + ++N Sbjct: 129 RKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYK---LDEDEDEDDADLSKYNL 185 Query: 205 SSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHS---AKNTPSQH 261 ++ D S S R S S + S+SSS S +P S S ++++ S Sbjct: 186 DASEEED-----SNKKKSNRRSRSKS--RSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQ 238 Query: 262 SHSIQHSPERSGS-GSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSS 320 S S S ERS S GS SSR +SP +RS + + + R SR RSS Sbjct: 239 SRSRSSSRERSRSRGSKSRSSSRSHRGSSSP-----RKRSYSSSSSSPERNRKRSRSRSS 293 Query: 321 FYPDGGDQETAKT 333 GD++ +T Sbjct: 294 ---SSGDRKKRRT 303 Score = 42.7 bits (99), Expect = 0.001 Identities = 40/131 (30%), Positives = 53/131 (40%), Gaps = 8/131 (6%) Query: 114 SPKRRSVSSQRSRSRSRRSYRSSRS--PRSSSSRSSSPYSKSPVSKRRG-SQEKQTKKAE 170 S K++S RS+SRS S SSRS P SS SRS S S S+ R S ++ ++ Sbjct: 193 SNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSR 252 Query: 171 GEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPS 230 G S + P+ S S + K S + S+ D R S S Sbjct: 253 GSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSS-----SSGDRKKRRTRSRS 307 Query: 231 PIATPPSQSSS 241 P S S S Sbjct: 308 PERRHRSSSGS 318 Score = 41.2 bits (95), Expect = 0.004 Identities = 39/154 (25%), Positives = 59/154 (38%), Gaps = 13/154 (8%) Query: 121 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK 180 +S+ S ++S R SRS SS SS S SP S R S+ + + + + S + Sbjct: 187 ASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSR 246 Query: 181 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS 240 +S+ S + S + G P +Y +S SP + S+SS Sbjct: 247 ERSR-----------SRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSR--SRSS 293 Query: 241 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGS 274 S D T + + S HS RS S Sbjct: 294 SSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSS 327 Score = 37.0 bits (84), Expect = 0.067 Identities = 34/142 (23%), Positives = 53/142 (37%), Gaps = 12/142 (8%) Query: 467 EEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDR 526 EE S ++KS R S H+R + + + R S+ Sbjct: 190 EEDSNKKKSNRRSRSKSRS-----SHSRSSSRSSSPSSSRSRSRSRSRSSSSS-----QS 239 Query: 527 RRKERSKERGDSKGSRESSGSRKQEKTPKDYK-EYKSYKDDSKHKREQDHSRSSSSSASP 585 R + S+ER S+GS+ S SR + K Y S + R++ SR SSSS Sbjct: 240 RSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSR-SSSSGDR 298 Query: 586 SSPSSREEKESKKEREEEFKTH 607 +R ++ R +H Sbjct: 299 KKRRTRSRSPERRHRSSSGSSH 320 >gi|6631100 natural killer-tumor recognition sequence [Homo sapiens] Length = 1462 Score = 71.2 bits (173), Expect = 3e-12 Identities = 184/826 (22%), Positives = 291/826 (35%), Gaps = 166/826 (20%) Query: 5 NSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNN 64 NS S S S SS S RS SR R SRS SR+Y+RSRS +SR Sbjct: 670 NSESDQSTYSKYSDRSSESSPRSRSRSSR--SRSYSRSYTRSRSLASSHSRS-------- 719 Query: 65 RGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRR----GRSRSRSPKRRSV 120 R R R Y Y + + R+ RR G+ S S K+ S Sbjct: 720 ----RSPSSRSHSRNKYSDHSQCSRSSSYTSISSDDGRRAKRRLRSSGKKNSVSHKKHSS 775 Query: 121 SSQ----------RSRSRSRRSYRSSRSP---RSSSSRSSSPYSKSPVSK-RRGSQEKQT 166 SS+ R RS R Y SRS S S +SS ++S K ++G E+ Sbjct: 776 SSEKTLHSKYVKGRDRSSCVRKYSESRSSLDYSSDSEQSSVQATQSAQEKEKQGQMERTH 835 Query: 167 KKAEGEPQEESPLKSKSQEE----PKDTFEHDPSESIDEFNKSSATS--GDIWPGLSAYD 220 K E EE KSKS+ E K T + + S+ + +K + G W S + Sbjct: 836 NKQEKNRGEE---KSKSERECPHSKKRTLKENLSDHLRNGSKPKRKNYAGSKWDSESNSE 892 Query: 221 -----NSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSG 275 NS H S + S S S+ +S +H K P+ S + P+ +G+ Sbjct: 893 RDVTKNSKNDSHPSSDKEEGEATSDSESE---VSEIH-IKVKPTTKSSTNTSLPDDNGAW 948 Query: 276 SVGNGSSRYSPSQNSPIHHIPSRRSPA--KTIAPQNAPRDESRGRSSFYPDGGDQETAKT 333 + S S+ S + +R P K + +N R+ T K Sbjct: 949 KSSKQRTSTSDSEGSCSNSENNRGKPQKHKHGSKENLKREH---------------TKKV 993 Query: 334 GKFLKSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLT 393 + LK K+ + K F + PL E ++ V + + S Sbjct: 994 KEKLKGKKDKKHKAPKRKQAFHWQPPLEF------GEEEEEEIDDKQVTQESKEKKVSEN 1047 Query: 394 KDRLLASTLVHSVKKEQEFRSIFDHIK----LPQASKSTSESFI--------QHIVSL-- 439 + + + L E++ D + L Q +K S+ I +++ L Sbjct: 1048 NETIKDNILKTEKSSEEDLSGKHDTVTVSSDLDQFTKDDSKLSISPTALNTEENVACLQN 1107 Query: 440 VHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQK----SPEIHRRIDISPSTLRKHTRL 495 + HV+E L + + + T + S+ K SP + R+D + + Sbjct: 1108 IQHVEESVPNGVEDVL-QTDDNMEICTPDRSSPAKVEETSPLGNARLDTPDINIVLKQDM 1166 Query: 496 AGEE---RVFKEENQKGDKKLRCD-------SADLRHDIDRRRKERSKERG-----DSKG 540 A E V K+E+ + K+ + SA L + K+ E+ D K Sbjct: 1167 ATEHPQAEVVKQESSMSESKVLGEVGKQDSSSASLASAGESTGKKEVAEKSQINLIDKKW 1226 Query: 541 S-----------------------------RESSGSRKQEKTPKDYKEYKSYKDDSKHKR 571 + G R + K+ + + + K R Sbjct: 1227 KPLQGVGNLAAPNAATSSAVEVKVLTTVPEMKPQGLRIEIKSKNKVRPGSLFDEVRKTAR 1286 Query: 572 EQDHSRSSSSSASPSSPS----SREEKESKKEREEEFKTHHEMKE--YSGFAGVSRPRGT 625 R+ SS+ +PS S+ S+ + E K+ H + YS SR + Sbjct: 1287 LNRRPRNQESSSDEQTPSRDDDSQSRSPSRSRSKSETKSRHRTRSVSYSHSRSRSRSSTS 1346 Query: 626 FFRIRG--RGRARGVFAGTNTGPNNSN--------TTFQKRPKEEEWDPEYTPKSKKYFL 675 +R R R R+RG ++ T +S+ T+ + R + +DP +S Y Sbjct: 1347 SYRSRSYSRSRSRGWYSRGRTRSRSSSYRSYKSHRTSSRSRSRSSSYDPHSRSRSYTY-- 1404 Query: 676 HDDRDDGVDYWAKRGRGRGTFQRG----RGRFNFKKSGSSPKWTHD 717 D + R R R QR RGR ++S S + D Sbjct: 1405 --------DSYYSRSRSRSRSQRSDSYHRGRSYNRRSRSCRSYGSD 1442 Score = 70.5 bits (171), Expect = 5e-12 Identities = 65/178 (36%), Positives = 84/178 (47%), Gaps = 20/178 (11%) Query: 4 SNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRN 63 S+ ++ S S+S+S SRSRS+S ++ + R+RS +YS SRSR R + YR Sbjct: 1298 SDEQTPSRDDDSQSRSPSRSRSKSETKSRH---RTRSVSYSHSRSRSRSSTSSYRS---- 1350 Query: 64 NRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVS-- 121 R Y R R RG+Y G R YR + R S S R RS S P RS S Sbjct: 1351 -----RSYS-RSRSRGWYSRGRTRSRSSSYRSYKSHRTS-SRSRSRSSSYDPHSRSRSYT 1403 Query: 122 --SQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEES 177 S SRSRSR RS RS RS + S+S S S+ ++ P E S Sbjct: 1404 YDSYYSRSRSRS--RSQRSDSYHRGRSYNRRSRSCRSYGSDSESDRSYSHHRSPSESS 1459 Score = 65.5 bits (158), Expect = 2e-10 Identities = 119/536 (22%), Positives = 202/536 (37%), Gaps = 80/536 (14%) Query: 93 YRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSP-RSSSSRSSSPYS 151 YRP + S+ + S RS+S QRSRS S Y S S R S Sbjct: 375 YRPPSGEKWSKGDKLSDPCSSRWDERSLS-QRSRSWSYNGYYSDLSTARHSGHHKKRRKE 433 Query: 152 KSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGD 211 K K++G ++K ++ + + + S + T S + ++SS+ Sbjct: 434 KKVKHKKKGKKQKHCRRHKQTKKRRILIPSDIESSKSSTRRMKSSCDRERSSRSSS---- 489 Query: 212 IWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPER 271 LS++ +S R S S D S HS++++ SHS +S Sbjct: 490 ----LSSHHSSKRD------------WSKSDKDVQS-SLTHSSRDSYRSKSHSQSYS--- 529 Query: 272 SGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETA 331 GSSR + S H R S+ RSS G ++ A Sbjct: 530 -------RGSSRSRTASKSSSHS-----------------RSRSKSRSS--SKSGHRKRA 563 Query: 332 KTGKFLKSPPLHKNLDAREKSTFREESPLRIKMIASDSH--RPEVKLKMAPVPLDDSNRP 389 + L +N + + PLR M +++ +P V + +PL DS P Sbjct: 564 SKSPRKTASQLSENKPVKTE-------PLRATMAQNENVVVQPVVAENIPVIPLSDSPPP 616 Query: 390 ASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFK 449 + + S ++ QE ++ H+ LP S + + + S +H +E+ + Sbjct: 617 SRWKPGQ---KPWKPSYERIQEMKAKTTHL-LPIQSTYSLANIKETGSSSSYHKREKNSE 672 Query: 450 SAAMTLNERFTSYQKATEEHSTRQKSPEIHRR-----IDISPSTLRKHTRLAGEERVFKE 504 S T ++ Y + E S R +S R S S H+R Sbjct: 673 SDQST----YSKYSDRSSESSPRSRSRSSRSRSYSRSYTRSRSLASSHSRSRSPSSRSHS 728 Query: 505 ENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKD--YKEYKS 562 N+ D +C + I R+K R S G + S +K + + + +Y Sbjct: 729 RNKYSDHS-QCSRSSSYTSISSDDGRRAKRRLRSSGKKNSVSHKKHSSSSEKTLHSKYVK 787 Query: 563 YKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEE---FKTHHEMKEYSG 615 +D S R+ SRSS +S S SS + +S +E+E++ +TH++ ++ G Sbjct: 788 GRDRSSCVRKYSESRSSLDYSSDSEQSSVQATQSAQEKEKQGQMERTHNKQEKNRG 843 Score = 65.1 bits (157), Expect = 2e-10 Identities = 142/631 (22%), Positives = 234/631 (37%), Gaps = 101/631 (16%) Query: 1 MGRSNSRSHSSRSKSRSQSSSRSR-----------SRSHSRKKRYSSRSRSRTYSRSRSR 49 M S R SSRS S S S R S +HS + Y S+S S++YSR SR Sbjct: 475 MKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQSYSRGSSR 534 Query: 50 DRMYSRDYRRDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGR 109 R S+ R R + HR +R S+SPR + Sbjct: 535 SRTASKS---------------SSHSRSRSKSRSSSKSGHR--------KRASKSPR--K 569 Query: 110 SRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKA 169 + S+ + + V ++ R+ ++ P + + P S SP R +K K + Sbjct: 570 TASQLSENKPVKTEPLRATMAQNENVVVQPVVAENIPVIPLSDSPPPSRWKPGQKPWKPS 629 Query: 170 EGEPQEESP-----LKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPR 224 QE L +S + E S S + K+S + + S +S Sbjct: 630 YERIQEMKAKTTHLLPIQSTYSLANIKETGSSSSYHKREKNSESDQSTYSKYSD-RSSES 688 Query: 225 SPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRY 284 SP S S + S S S + + L++ HS +PS SHS ++Y Sbjct: 689 SPRSRSRSSRSRSYSRSYTRSRSLASSHSRSRSPSSRSHS----------------RNKY 732 Query: 285 SPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKS--PPL 342 S H SR S +I+ + R + R RSS G + + K S L Sbjct: 733 SD------HSQCSRSSSYTSISSDDGRRAKRRLRSS-----GKKNSVSHKKHSSSSEKTL 781 Query: 343 H-KNLDAREKST-FREESPLRIKM-IASDSHRPEV--------KLKMAPVPLDDSNRPAS 391 H K + R++S+ R+ S R + +SDS + V K K + + + + Sbjct: 782 HSKYVKGRDRSSCVRKYSESRSSLDYSSDSEQSSVQATQSAQEKEKQGQMERTHNKQEKN 841 Query: 392 LTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSA 451 +++ + KK ++ DH++ SK +++ + + K++ Sbjct: 842 RGEEKSKSERECPHSKKRTLKENLSDHLR--NGSKPKRKNYAGSKWDSESNSERDVTKNS 899 Query: 452 AMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRK-HTRLAGEERVFKEENQKGD 510 N+ S K E ++ +S I + P+T +T L + +K Q Sbjct: 900 K---NDSHPSSDKEEGEATSDSESEVSEIHIKVKPTTKSSTNTSLPDDNGAWKSSKQ--- 953 Query: 511 KKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHK 570 R ++D R K + GS+E + K+E T K KE K D KHK Sbjct: 954 ---RTSTSDSEGSCSNSENNRGKPQKHKHGSKE---NLKREHT-KKVKEKLKGKKDKKHK 1006 Query: 571 REQDHSRSSSSSASPSSPSSREEKESKKERE 601 + R + P EE+E +++ Sbjct: 1007 APK---RKQAFHWQPPLEFGEEEEEEIDDKQ 1034 Score = 63.5 bits (153), Expect = 7e-10 Identities = 147/688 (21%), Positives = 235/688 (34%), Gaps = 108/688 (15%) Query: 2 GRSNSRSHS---SRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYR 58 GR R H+ SRS S S S + H +++ R R Y R S ++ D Sbjct: 335 GRGTIRYHTPPRSRSCSESDDDDSSETPPHWKEEM----QRLRAY-RPPSGEKWSKGDKL 389 Query: 59 RDYRNNRGMRRPYGYRGRG---RGYYQGGGGRYHRG----------------GYRPVWNR 99 D ++R R R R GYY H G G + R Sbjct: 390 SDPCSSRWDERSLSQRSRSWSYNGYYSDLSTARHSGHHKKRRKEKKVKHKKKGKKQKHCR 449 Query: 100 RHSR-----------------SPRRGRS---RSRSPKRRSVSSQRSRSR----------- 128 RH + S RR +S R RS + S+SS S R Sbjct: 450 RHKQTKKRRILIPSDIESSKSSTRRMKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQS 509 Query: 129 -----SRRSYRS---SRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK 180 SR SYRS S+S SSRS + S S+ R +K + +SP K Sbjct: 510 SLTHSSRDSYRSKSHSQSYSRGSSRSRTASKSSSHSRSRSKSRSSSKSGHRKRASKSPRK 569 Query: 181 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS 240 + SQ + +P + N++ + +N P P S SP PPS+ Sbjct: 570 TASQLSENKPVKTEPLRATMAQNENVVVQPVV------AENIPVIPLSDSP---PPSRWK 620 Query: 241 SCSD--APMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSR 298 P + K + H IQ + + G+ SS + +NS S Sbjct: 621 PGQKPWKPSYERIQEMK-AKTTHLLPIQSTYSLANIKETGSSSSYHKREKNSESDQ--ST 677 Query: 299 RSPAKTIAPQNAPRDESR-GRSSFYPDGGDQETAKTGKFLKSPPLHKNLDAREKSTFREE 357 S + +++PR SR RS Y + + +S +R K + + Sbjct: 678 YSKYSDRSSESSPRSRSRSSRSRSYSRSYTRSRSLASSHSRSRSPSSRSHSRNKYSDHSQ 737 Query: 358 ---SPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHS------VKK 408 S + + D R + +L+ + S++ S + ++ L S V V+K Sbjct: 738 CSRSSSYTSISSDDGRRAKRRLRSSGKKNSVSHKKHSSSSEKTLHSKYVKGRDRSSCVRK 797 Query: 409 EQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEE 468 E RS D+ S + +S +Q S ++ K M + E+ Sbjct: 798 YSESRSSLDY------SSDSEQSSVQATQS-----AQEKEKQGQMERTHNKQEKNRGEEK 846 Query: 469 HSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRR 528 + ++ P H + L H R + + K D + + ++ + Sbjct: 847 SKSERECP--HSKKRTLKENLSDHLRNGSKPKRKNYAGSKWDSESNSERDVTKNSKNDSH 904 Query: 529 KERSKERGDSKGSRESSGSR---KQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASP 585 KE G++ ES S K + T K D+ K + + +S S S Sbjct: 905 PSSDKEEGEATSDSESEVSEIHIKVKPTTKSSTNTSLPDDNGAWKSSKQRTSTSDSEGSC 964 Query: 586 SSPSSREEKESKKER--EEEFKTHHEMK 611 S+ + K K + +E K H K Sbjct: 965 SNSENNRGKPQKHKHGSKENLKREHTKK 992 Score = 61.6 bits (148), Expect = 3e-09 Identities = 57/144 (39%), Positives = 66/144 (45%), Gaps = 11/144 (7%) Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYR 62 RS S SHS RS+SRS +SS RSRS+SR + SR RT SRS S R Y+ Sbjct: 1330 RSVSYSHS-RSRSRSSTSSY-RSRSYSRSRSRGWYSRGRTRSRSSS-----YRSYKSHRT 1382 Query: 63 NNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSS 122 ++R R Y R Y R R R RS R RS + + RS S Sbjct: 1383 SSRSRSRSSSYDPHSRSRSYTYDSYYSRSRSR----SRSQRSDSYHRGRSYNRRSRSCRS 1438 Query: 123 QRSRSRSRRSYRSSRSPRSSSSRS 146 S S S RSY RSP SS S Sbjct: 1439 YGSDSESDRSYSHHRSPSESSRYS 1462 Score = 42.0 bits (97), Expect = 0.002 Identities = 119/572 (20%), Positives = 201/572 (35%), Gaps = 79/572 (13%) Query: 111 RSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAE 170 + R S S S + S S SS S + + P KR + K+ +E Sbjct: 187 KKRKKPTHSEGSDSSSNSSSSSESSSESELEHERSRRRKHKRRPKVKRSKKRRKEASSSE 246 Query: 171 GEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPS 230 EP+ + + K E DT E +S + K +I P + Sbjct: 247 -EPRNKHAMNPKGHSERSDTNEKRSVDSSAKREKPVVRPEEIPP----VPENRFLLRRDM 301 Query: 231 PIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQ-------HSPERSGSGSVG--NGS 281 P+ T + AP++S K + S+ I+ H+P RS S S + S Sbjct: 302 PVVTAEPEPKIPDVAPIVS---DQKPSVSKSGRKIKGRGTIRYHTPPRSRSCSESDDDDS 358 Query: 282 SRYSPSQNSPIHHIPSRRSPA--------KTIAPQNAPRDE----SRGRS----SFYPD- 324 S P + + + R P+ K P ++ DE R RS +Y D Sbjct: 359 SETPPHWKEEMQRLRAYRPPSGEKWSKGDKLSDPCSSRWDERSLSQRSRSWSYNGYYSDL 418 Query: 325 -----GGDQETAKTGKFLKSPPLHKNLDAREKSTFR-EESPLRIKMIASD--SHRPEVKL 376 G + + K +K HK ++K R +++ R +I SD S + + Sbjct: 419 STARHSGHHKKRRKEKKVK----HKKKGKKQKHCRRHKQTKKRRILIPSDIESSKSSTRR 474 Query: 377 KMAPVPLDDSNRPASLT-----------KDRLLASTLVHSVK-------KEQEFRSIFDH 418 + + S+R +SL+ D+ + S+L HS + Q + Sbjct: 475 MKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQSYSRGSSR 534 Query: 419 IKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATE-------EHST 471 + S S S S + S +++ KS T ++ + TE ++ Sbjct: 535 SRTASKSSSHSRSRSKSRSSSKSGHRKRASKSPRKTASQLSENKPVKTEPLRATMAQNEN 594 Query: 472 RQKSPEIHRRIDISP-STLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKE 530 P + I + P S +R ++ +K ++ ++++ + L Sbjct: 595 VVVQPVVAENIPVIPLSDSPPPSRWKPGQKPWKPSYER-IQEMKAKTTHLLPIQSTYSLA 653 Query: 531 RSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSS-SSSASPSSPS 589 KE G S SS ++++ + D Y Y D S + SRSS S S S S Sbjct: 654 NIKETGSS-----SSYHKREKNSESDQSTYSKYSDRSSESSPRSRSRSSRSRSYSRSYTR 708 Query: 590 SREEKESKKEREEEFKTHHEMKEYSGFAGVSR 621 SR S H +YS + SR Sbjct: 709 SRSLASSHSRSRSPSSRSHSRNKYSDHSQCSR 740 Score = 41.2 bits (95), Expect = 0.004 Identities = 88/386 (22%), Positives = 148/386 (38%), Gaps = 69/386 (17%) Query: 273 GSGSVGNGSSRYSPSQNSPIHHIPSRRSP---------AKTIAPQNAPRDESRGRSSFYP 323 GS S N SS S S + H SRR +K + + +E R + + P Sbjct: 197 GSDSSSNSSSSSESSSESELEHERSRRRKHKRRPKVKRSKKRRKEASSSEEPRNKHAMNP 256 Query: 324 DGGDQETAKTGKFLKSPPLHKNLDA---REKSTFREES----PLRIKMIASD----SHRP 372 G + + K +++D+ REK R E P ++ D + P Sbjct: 257 KGHSERSDTNEK--------RSVDSSAKREKPVVRPEEIPPVPENRFLLRRDMPVVTAEP 308 Query: 373 EVKLK-MAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSES 431 E K+ +AP+ S++ S++K S +K + +I H P S+S SES Sbjct: 309 EPKIPDVAPIV---SDQKPSVSK----------SGRKIKGRGTIRYHT--PPRSRSCSES 353 Query: 432 FIQHIVSLVHHVKE--QYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRI------- 482 H KE Q ++ E+++ K ++ S+R + +R Sbjct: 354 DDDDSSETPPHWKEEMQRLRAYRPPSGEKWSKGDKLSDPCSSRWDERSLSQRSRSWSYNG 413 Query: 483 ---DISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSK 539 D+S + H + +E+ K + +KG K+ C RR K+ K R Sbjct: 414 YYSDLSTARHSGHHKKRRKEKKVKHK-KKGKKQKHC----------RRHKQTKKRRILIP 462 Query: 540 GSRESSGS--RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESK 597 ESS S R+ + + + +S S H ++D S+S S + SSR+ SK Sbjct: 463 SDIESSKSSTRRMKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSK 522 Query: 598 KEREEEFKTHHEMKEYSGFAGVSRPR 623 + + + S + SR R Sbjct: 523 SHSQSYSRGSSRSRTASKSSSHSRSR 548 Score = 39.3 bits (90), Expect = 0.013 Identities = 124/680 (18%), Positives = 232/680 (34%), Gaps = 119/680 (17%) Query: 7 RSHSSRSKSRSQSSSRS-RSRSHSRKKRYSSRSRSRTYSRSRSRDRMY--------SRDY 57 R+H+ + K+R + S+S R HS+K+ + S+ + + Y S Sbjct: 833 RTHNKQEKNRGEEKSKSERECPHSKKRTLKENLSDHLRNGSKPKRKNYAGSKWDSESNSE 892 Query: 58 RRDYRNNRGMRRPYGYRGRGRGYYQGGG--GRYHRGGYRPVWNRRHSRSPRRGRSRSRSP 115 R +N++ P + G H + ++ P + S Sbjct: 893 RDVTKNSKNDSHPSSDKEEGEATSDSESEVSEIHIKVKPTTKSSTNTSLPDDNGAWKSSK 952 Query: 116 KRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSS--SPYSKSPVSKRRGSQEKQTKKAE--- 170 +R S S + + R S+ + ++K K +G ++K+ K + Sbjct: 953 QRTSTSDSEGSCSNSENNRGKPQKHKHGSKENLKREHTKKVKEKLKGKKDKKHKAPKRKQ 1012 Query: 171 ----------GEPQEESPLKSKSQEEPKDTFEHDPSESI-DEFNKSSATSGDIWPGLSAY 219 GE +EE + +E K+ + +E+I D K+ +S + G Sbjct: 1013 AFHWQPPLEFGEEEEEEIDDKQVTQESKEKKVSENNETIKDNILKTEKSSEEDLSG---- 1068 Query: 220 DNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHS--HSIQHSPERSGSGSV 277 H +++ Q + D LS +A NT + +IQH E SV Sbjct: 1069 ------KHDTVTVSSDLDQFTK--DDSKLSISPTALNTEENVACLQNIQHVEE-----SV 1115 Query: 278 GNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFL 337 NG + ++ P R SPAK +ET+ G Sbjct: 1116 PNGVEDVLQTDDNMEICTPDRSSPAKV-----------------------EETSPLGNAR 1152 Query: 338 KSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPA------S 391 P +++ K E P + +++ +S E K+ + V DS+ + S Sbjct: 1153 LDTP---DINIVLKQDMATEHP-QAEVVKQESSMSESKV-LGEVGKQDSSSASLASAGES 1207 Query: 392 LTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSA 451 K + + ++ + K+ + ++ P A+ TS + +++ V +K Q + Sbjct: 1208 TGKKEVAEKSQINLIDKKWKPLQGVGNLAAPNAA--TSSAVEVKVLTTVPEMKPQGLRIE 1265 Query: 452 AMTLNE-----------------RFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTR 494 + N+ R Q+++ + T + + R SPS R + Sbjct: 1266 IKSKNKVRPGSLFDEVRKTARLNRRPRNQESSSDEQTPSRDDDSQSR---SPSRSRSKSE 1322 Query: 495 LAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKER-------SKERGDS----KGSRE 543 R + R ++ R R + R ++ R S K R Sbjct: 1323 TKSRHRTRSVSYSHSRSRSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSSYRSYKSHRT 1382 Query: 544 SSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKE------SK 597 SS SR + + + +SY DS + R + SRS S + S S Sbjct: 1383 SSRSRSRSSSYDPHSRSRSYTYDSYYSRSRSRSRSQRSDSYHRGRSYNRRSRSCRSYGSD 1442 Query: 598 KEREEEFKTHHEMKEYSGFA 617 E + + H E S ++ Sbjct: 1443 SESDRSYSHHRSPSESSRYS 1462 >gi|126723149 chromosome 19 open reading frame 29 [Homo sapiens] Length = 758 Score = 70.9 bits (172), Expect = 4e-12 Identities = 69/222 (31%), Positives = 94/222 (42%), Gaps = 31/222 (13%) Query: 3 RSNSRSHSSRSKSR-SQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDY 61 RS SRS R + R SQS SRSRSRSH R R+R R R R R SR+ R D Sbjct: 6 RSRSRSAGRRGRRRQSQSGSRSRSRSHGR------RNRRRREDEGRRRRRRRSRERRSDS 59 Query: 62 RNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVS 121 R R G R RP W HSR G S+S S + +S Sbjct: 60 EEERWQR----------------SGMRSRSPPRPKW---HSRD---GSSQSDSGEEQSRG 97 Query: 122 SQRSRSRSRRSYRSSRSPRSSSS--RSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPL 179 R R RS+ S S SS+S RS SP + + ++ S +++ + E Q+E + Sbjct: 98 QWARRRRRARSWSPSSSASSSASPGRSQSPRAAAAALSQQQSLQERLRLREERKQQEELM 157 Query: 180 KSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDN 221 K+ E K E+ + + G+ + G + DN Sbjct: 158 KAFETPEEKRARRLAKKEAKERKKREKMGWGEEYMGYTNTDN 199 Score = 34.7 bits (78), Expect = 0.33 Identities = 39/132 (29%), Positives = 49/132 (37%), Gaps = 24/132 (18%) Query: 62 RNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVS 121 R+ R R G RGR R G R +R H R RR R +RR Sbjct: 3 RDTRSRSRSAGRRGRRRQSQSGSRSR----------SRSHGRRNRRRREDEGRRRRR--- 49 Query: 122 SQRSRSRS--------RRSYRSSRSPRSSS--SRSSSPYSKSPVSKRRGSQEKQTKKAEG 171 +RSR R +RS SRSP SR S S S + RG ++ ++A Sbjct: 50 -RRSRERRSDSEEERWQRSGMRSRSPPRPKWHSRDGSSQSDSGEEQSRGQWARRRRRARS 108 Query: 172 EPQEESPLKSKS 183 S S S Sbjct: 109 WSPSSSASSSAS 120 Score = 31.2 bits (69), Expect = 3.7 Identities = 35/122 (28%), Positives = 51/122 (41%), Gaps = 36/122 (29%) Query: 526 RRRKERSKER-GDSKGSR-ESSGSRKQEKT-PKDYKEYKSYKDDS-------------KH 569 RRR+ RS+ER DS+ R + SG R + PK + S + DS + Sbjct: 46 RRRRRRSRERRSDSEEERWQRSGMRSRSPPRPKWHSRDGSSQSDSGEEQSRGQWARRRRR 105 Query: 570 KREQDHSRSSSSSASPSSPSS--------------------REEKESKKEREEEFKTHHE 609 R S S+SSSASP S REE++ ++E + F+T E Sbjct: 106 ARSWSPSSSASSSASPGRSQSPRAAAAALSQQQSLQERLRLREERKQQEELMKAFETPEE 165 Query: 610 MK 611 + Sbjct: 166 KR 167 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.308 0.124 0.351 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 32,326,211 Number of Sequences: 37866 Number of extensions: 1828768 Number of successful extensions: 34103 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 436 Number of HSP's successfully gapped in prelim test: 1010 Number of HSP's that attempted gapping in prelim test: 13674 Number of HSP's gapped (non-prelim): 10423 length of query: 747 length of database: 18,247,518 effective HSP length: 110 effective length of query: 637 effective length of database: 14,082,258 effective search space: 8970398346 effective search space used: 8970398346 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.