Search of human proteins with 10863967

Search of human proteins with 10863967

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|10863967 hairy and enhancer of split 4 isoform 2 [Homo
sapiens]
         (221 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|10863967 hairy and enhancer of split 4 isoform 2 [Homo sapiens]    442   e-124
gi|216548627 hairy and enhancer of split 4 isoform 1 [Homo sapiens]   428   e-120
gi|5031763 hairy and enhancer of split 1 [Homo sapiens]               236   1e-62
gi|63055047 hairy and enhancer of split homolog 2 [Homo sapiens]      120   7e-28
gi|145207994 hairy and enhancer of split 7 [Homo sapiens]              97   1e-20
gi|7657154 hairy/enhancer-of-split related with YRPW motif-like ...    93   2e-19
gi|105990528 hairy/enhancer-of-split related with YRPW motif 1 i...    91   1e-18
gi|218751874 hairy and enhancer of split 6 isoform b [Homo sapiens]    89   3e-18
gi|21361763 hairy and enhancer of split 6 isoform a [Homo sapiens]     89   4e-18
gi|105990526 hairy/enhancer-of-split related with YRPW motif 1 i...    88   7e-18
gi|6912414 hairy/enhancer-of-split related with YRPW motif 2 [Ho...    87   1e-17
gi|58219048 hairy and enhancer of split 5 [Homo sapiens]               80   1e-15
gi|66912172 hairy and enhancer of split 3 [Homo sapiens]               79   2e-15
gi|13540521 basic helix-loop-helix domain containing, class B, 3...    63   2e-10
gi|4503299 basic helix-loop-helix family, member e40 [Homo sapiens]    60   1e-09
gi|71274142 HES/HEY-like transcription factor [Homo sapiens]           54   1e-07
gi|119703742 vitelliform macular dystrophy 2-like 1 [Homo sapiens]     40   0.001
gi|9945318 MAX binding protein [Homo sapiens]                          39   0.003
gi|91208437 GEM interacting protein [Homo sapiens]                     39   0.004
gi|29789008 Huntingtin interacting protein C isoform 2 [Homo sap...    39   0.005
gi|72534686 Huntingtin interacting protein C isoform 1 [Homo sap...    39   0.005
gi|192807323 SWI/SNF-related matrix-associated actin-dependent r...    38   0.006
gi|192807320 SWI/SNF-related matrix-associated actin-dependent r...    38   0.006
gi|192807318 SWI/SNF-related matrix-associated actin-dependent r...    38   0.006
gi|192807316 SWI/SNF-related matrix-associated actin-dependent r...    38   0.006
gi|192807314 SWI/SNF-related matrix-associated actin-dependent r...    38   0.006
gi|192807312 SWI/SNF-related matrix-associated actin-dependent r...    38   0.006
gi|21071056 SWI/SNF-related matrix-associated actin-dependent re...    38   0.006
gi|148613882 homeobox A4 [Homo sapiens]                                38   0.006
gi|59853099 dynamin 1 isoform 1 [Homo sapiens]                         38   0.006

>gi|10863967 hairy and enhancer of split 4 isoform 2 [Homo sapiens]
          Length = 221

 Score =  442 bits (1137), Expect = e-124
 Identities = 221/221 (100%), Positives = 221/221 (100%)

Query: 1   MAADTPGKPSASPMAGAPASASRTPDKPRSAAEHRKSSKPVMEKRRRARINESLAQLKTL 60
           MAADTPGKPSASPMAGAPASASRTPDKPRSAAEHRKSSKPVMEKRRRARINESLAQLKTL
Sbjct: 1   MAADTPGKPSASPMAGAPASASRTPDKPRSAAEHRKSSKPVMEKRRRARINESLAQLKTL 60

Query: 61  ILDALRKESSRHSKLEKADILEMTVRHLRSLRRVQVTAALSADPAVLGKYRAGFHECLAE 120
           ILDALRKESSRHSKLEKADILEMTVRHLRSLRRVQVTAALSADPAVLGKYRAGFHECLAE
Sbjct: 61  ILDALRKESSRHSKLEKADILEMTVRHLRSLRRVQVTAALSADPAVLGKYRAGFHECLAE 120

Query: 121 VNRFLAGCEGVPADVRSRLLGHLAACLRQLGPSRRPASLSPAAPAEAPAPEVYAGRPLLP 180
           VNRFLAGCEGVPADVRSRLLGHLAACLRQLGPSRRPASLSPAAPAEAPAPEVYAGRPLLP
Sbjct: 121 VNRFLAGCEGVPADVRSRLLGHLAACLRQLGPSRRPASLSPAAPAEAPAPEVYAGRPLLP 180

Query: 181 SLGGPFPLLAPPLLPGLTRALPAAPRAGPQGPGGPWRPWLR 221
           SLGGPFPLLAPPLLPGLTRALPAAPRAGPQGPGGPWRPWLR
Sbjct: 181 SLGGPFPLLAPPLLPGLTRALPAAPRAGPQGPGGPWRPWLR 221


>gi|216548627 hairy and enhancer of split 4 isoform 1 [Homo sapiens]
          Length = 247

 Score =  428 bits (1100), Expect = e-120
 Identities = 221/247 (89%), Positives = 221/247 (89%), Gaps = 26/247 (10%)

Query: 1   MAADTPGKPSASPMAGAPASASRTPDKPRSAAEHRK------------------------ 36
           MAADTPGKPSASPMAGAPASASRTPDKPRSAAEHRK                        
Sbjct: 1   MAADTPGKPSASPMAGAPASASRTPDKPRSAAEHRKVGSRPGVRGATGGREGRGTQPVPD 60

Query: 37  --SSKPVMEKRRRARINESLAQLKTLILDALRKESSRHSKLEKADILEMTVRHLRSLRRV 94
             SSKPVMEKRRRARINESLAQLKTLILDALRKESSRHSKLEKADILEMTVRHLRSLRRV
Sbjct: 61  PQSSKPVMEKRRRARINESLAQLKTLILDALRKESSRHSKLEKADILEMTVRHLRSLRRV 120

Query: 95  QVTAALSADPAVLGKYRAGFHECLAEVNRFLAGCEGVPADVRSRLLGHLAACLRQLGPSR 154
           QVTAALSADPAVLGKYRAGFHECLAEVNRFLAGCEGVPADVRSRLLGHLAACLRQLGPSR
Sbjct: 121 QVTAALSADPAVLGKYRAGFHECLAEVNRFLAGCEGVPADVRSRLLGHLAACLRQLGPSR 180

Query: 155 RPASLSPAAPAEAPAPEVYAGRPLLPSLGGPFPLLAPPLLPGLTRALPAAPRAGPQGPGG 214
           RPASLSPAAPAEAPAPEVYAGRPLLPSLGGPFPLLAPPLLPGLTRALPAAPRAGPQGPGG
Sbjct: 181 RPASLSPAAPAEAPAPEVYAGRPLLPSLGGPFPLLAPPLLPGLTRALPAAPRAGPQGPGG 240

Query: 215 PWRPWLR 221
           PWRPWLR
Sbjct: 241 PWRPWLR 247


>gi|5031763 hairy and enhancer of split 1 [Homo sapiens]
          Length = 280

 Score =  236 bits (602), Expect = 1e-62
 Identities = 129/217 (59%), Positives = 151/217 (69%), Gaps = 17/217 (7%)

Query: 1   MAADTPGKPSASPMAGAPASASRTPDKPRSAAEHRKSSKPVMEKRRRARINESLAQLKTL 60
           M AD   K S+SP+A  PAS + TPDKP++A+EHRKSSKP+MEKRRRARINESL+QLKTL
Sbjct: 1   MPADIMEKNSSSPVAATPASVNTTPDKPKTASEHRKSSKPIMEKRRRARINESLSQLKTL 60

Query: 61  ILDALRKESSRHSKLEKADILEMTVRHLRSLRRVQVTAALSADPAVLGKYRAGFHECLAE 120
           ILDAL+K+SSRHSKLEKADILEMTV+HLR+L+R Q+TAALS DP+VLGKYRAGF EC+ E
Sbjct: 61  ILDALKKDSSRHSKLEKADILEMTVKHLRNLQRAQMTAALSTDPSVLGKYRAGFSECMNE 120

Query: 121 VNRFLAGCEGVPADVRSRLLGHLAACLRQLGPSRRPASLSPAAPAEAPAPEVYAGRPLLP 180
           V RFL+ CEGV  +VR+RLLGHLA C+ Q+     P    PA  A  P P         P
Sbjct: 121 VTRFLSTCEGVNTEVRTRLLGHLANCMTQINAMTYPGQPHPALQAPPPPP---------P 171

Query: 181 SLGGP--FPLLAPPLLPGLTRALPAAPRAGPQGPGGP 215
             GGP   P   PP L      +P    A P   G P
Sbjct: 172 GPGGPQHAPFAPPPPL------VPIPGGAAPPPGGAP 202


>gi|63055047 hairy and enhancer of split homolog 2 [Homo sapiens]
          Length = 173

 Score =  120 bits (302), Expect = 7e-28
 Identities = 85/197 (43%), Positives = 105/197 (53%), Gaps = 29/197 (14%)

Query: 25  PDKPRSAAEHRKSSKPVMEKRRRARINESLAQLKTLILDALRKESSRHSKLEKADILEMT 84
           P +   AAE RKS KP++EKRRRARIN+SL+QLK LIL  L +E+S  SKLEKAD+LEMT
Sbjct: 4   PRRAGDAAELRKSLKPLLEKRRRARINQSLSQLKGLILPLLGRENSNCSKLEKADVLEMT 63

Query: 85  VRHLRSLRRVQVTAALSADPAVLGKYRAGFHECLAEVNRFLAGCEGVPADVRSRLLGHL- 143
           VR L+ L     ++  +A P     YR G+  C+A + R L  C  +   V +RLL HL 
Sbjct: 64  VRFLQEL---PASSWPTAAPLPCDSYREGYSACVARLARVLPACRVLEPAVSARLLEHLW 120

Query: 144 -AACLRQLGPSRRPASLSPAAPAEAPAPEVYAGRPLLPSLGGPFPLLAPPLLPGLTRALP 202
             A    L   R   S  P+APA APA               P P  AP  +P      P
Sbjct: 121 RRAASATLDGGRAGDSSGPSAPAPAPA-------------SAPEPASAP--VPS-----P 160

Query: 203 AAPRAGPQGPGGPWRPW 219
            +P  GP    G WRPW
Sbjct: 161 PSPPCGP----GLWRPW 173


>gi|145207994 hairy and enhancer of split 7 [Homo sapiens]
          Length = 225

 Score = 97.1 bits (240), Expect = 1e-20
 Identities = 84/226 (37%), Positives = 108/226 (47%), Gaps = 40/226 (17%)

Query: 29  RSAAEHR---KSSKPVMEKRRRARINESLAQLKTLILDALRKESSRHSKLEKADILEMTV 85
           R  AE+R   K  KP++EKRRR RIN SL +L+ L+L+  R ++ R+ KLEKA+ILE  V
Sbjct: 4   RDRAENRDGPKMLKPLVEKRRRDRINRSLEELRLLLLERTRDQNLRNPKLEKAEILEFAV 63

Query: 86  RHLRSLRRVQ----VTAALSADPAVLGKYRAGFHECLAEVNRFLAGCEGVPADVRSRLLG 141
            +LR   RV+      + +    A+   Y +GF ECL  +  F    +  PA  R++L  
Sbjct: 64  GYLRERSRVEPPGVPRSPVQDAEALASCYLSGFRECLLRLAAF--AHDASPA-ARAQLFS 120

Query: 142 HLAACLRQLGPSRRPA---------SLSPAAPAEAPA----PEVYAGRP-----LLPSL- 182
            L   LR   P  +P          SL PAAPA  PA    P V+ G P       PSL 
Sbjct: 121 ALHGYLRPKPPRPKPVDPRPPAPRPSLDPAAPALGPALHQRPPVHQGHPSPRCAWSPSLC 180

Query: 183 -------GGPFPL--LAPPLLPGLTRALPAAPRAGPQGPGGPWRPW 219
                  G P PL  L PP  P        AP+A    P   WRPW
Sbjct: 181 SPRAGDSGAPAPLTGLLPP--PPPPHRQDGAPKAPLPPPPAFWRPW 224


>gi|7657154 hairy/enhancer-of-split related with YRPW motif-like
           [Homo sapiens]
          Length = 328

 Score = 93.2 bits (230), Expect = 2e-19
 Identities = 69/184 (37%), Positives = 95/184 (51%), Gaps = 17/184 (9%)

Query: 30  SAAEHRKSSKPVMEKRRRARINESLAQLKTLILDALRKESSRHSKLEKADILEMTVRHLR 89
           S  + RK  + ++EKRRR RIN SL++L+ L+  A  K+ S  SKLEKA++L+MTV HL+
Sbjct: 39  SQMQARKKRRGIIEKRRRDRINSSLSELRRLVPTAFEKQGS--SKLEKAEVLQMTVDHLK 96

Query: 90  SLRRVQVTAALSADPAVLGKYRAGFHECLAEVNRFLAGCEGVPA---DVRSRLLGHLAAC 146
            L     T    A    +     GF ECL EV R+L   EG  +    VR RLL HL + 
Sbjct: 97  MLHATGGTGFFDARALAVDFRSIGFRECLTEVIRYLGVLEGPSSRADPVRIRLLSHLNSY 156

Query: 147 LRQLGPSRRPASLSPAAPAEAPA--PEVYAGRPLLPSLGGPFPLLA---PPLLPGLTRAL 201
             ++ PS      +P  P   PA     +   P LP+L     +L     P+LPG++   
Sbjct: 157 AAEMEPSP-----TPTGPLAFPAWPWSFFHSCPGLPALSNQLAILGRVPSPVLPGVSS-- 209

Query: 202 PAAP 205
           PA P
Sbjct: 210 PAYP 213



 Score = 28.9 bits (63), Expect = 3.6
 Identities = 27/86 (31%), Positives = 32/86 (37%), Gaps = 5/86 (5%)

Query: 138 RLLGHLAACLRQLGPSRRPASLSPAAPAEAPA---PEVYAGRPLLPSLGGPFPLLAPPLL 194
           R  G +    R + PSR  +S   A P E PA   P   + R    S   P    + P  
Sbjct: 224 RATGIILPARRNVLPSRGASSTRRARPLERPATPVPVAPSSRAARSSHIAPLLQSSSPTP 283

Query: 195 PGLT--RALPAAPRAGPQGPGGPWRP 218
           PG T   A  A P      PG   RP
Sbjct: 284 PGPTGSAAYVAVPTPNSSSPGPAGRP 309


>gi|105990528 hairy/enhancer-of-split related with YRPW motif 1
           isoform a [Homo sapiens]
          Length = 304

 Score = 90.5 bits (223), Expect = 1e-18
 Identities = 76/199 (38%), Positives = 96/199 (48%), Gaps = 21/199 (10%)

Query: 35  RKSSKPVMEKRRRARINESLAQLKTLILDALRKESSRHSKLEKADILEMTVRHLRSLRRV 94
           RK  + ++EKRRR RIN SL++L+ L+  A  K+ S  +KLEKA+IL+MTV HL+ L   
Sbjct: 50  RKRRRGIIEKRRRDRINNSLSELRRLVPSAFEKQGS--AKLEKAEILQMTVDHLKMLHTA 107

Query: 95  QVTAALSADPAVLGKYRAGFHECLAEVNRFLAGCEGVPAD--VRSRLLGHLAACLRQLGP 152
                  A    +     GF ECLAEV R+L+  EG+ A   +R RL+ H    L     
Sbjct: 108 GGKGYFDAHALAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSH----LNNYAS 163

Query: 153 SRRPASLSPAAPAEAPAPEVYAGRP------LLPSLG-GPFPLLAPPLLP----GLTRAL 201
            R  AS + A     P   V+   P      LLP  G G     A P  P     L  A 
Sbjct: 164 QREAASGAHAGLGHIPWGTVFGHHPHIAHPLLLPQNGHGNAGTTASPTEPHHQGRLGSAH 223

Query: 202 PAAP--RAGPQGPGGPWRP 218
           P AP  RA P G  GP  P
Sbjct: 224 PEAPALRAPPSGSLGPVLP 242


>gi|218751874 hairy and enhancer of split 6 isoform b [Homo sapiens]
          Length = 222

 Score = 89.0 bits (219), Expect = 3e-18
 Identities = 69/232 (29%), Positives = 100/232 (43%), Gaps = 34/232 (14%)

Query: 11  ASPMAGAPASASRTPDKPRSAAEHRKSSKPVMEKRRRARINESLAQLKTLILDALRKESS 70
           A P A       R  +        RK+ KP++EK+RRARINESL +L+ L+  A      
Sbjct: 2   APPAAPGRDRVGREDEDGWETRGDRKARKPLVEKKRRARINESLQELRLLLAGA------ 55

Query: 71  RHSKLEKADILEMTVRHLRSLRRVQVTAALSADPAVLGKYRAGFHECLAEVNRFLAGCEG 130
             +KLE A++LE+TVR ++ + R +             ++ AG+ +C+ EV+ F++ C+ 
Sbjct: 56  -EAKLENAEVLELTVRRVQGVLRGRAREREQLQAEASERFAAGYIQCMHEVHTFVSTCQA 114

Query: 131 VPADVRSRLLGHLAACLRQLGPSRRPASLS----------PAAPAEAPAPEVYAGRPLLP 180
           + A V + LL HL   +    P R  +S            P AP  +  P   A    +P
Sbjct: 115 IDATVAAELLNHLLESM----PLREGSSFQDLLGDALAGPPRAPGRSGWPAGGAPGSPIP 170

Query: 181 SLGGPFPLLAPPLLPGLTRALPAAPRAGP-------------QGPGGPWRPW 219
           S  GP   L   L       L  AP  GP             Q     WRPW
Sbjct: 171 SPPGPGDDLCSDLEEAPEAELSQAPAEGPDLVPAALGSLTTAQIARSVWRPW 222


>gi|21361763 hairy and enhancer of split 6 isoform a [Homo sapiens]
          Length = 224

 Score = 88.6 bits (218), Expect = 4e-18
 Identities = 69/232 (29%), Positives = 100/232 (43%), Gaps = 32/232 (13%)

Query: 11  ASPMAGAPASASRTPDKPRSAAEHRKSSKPVMEKRRRARINESLAQLKTLILDALRKESS 70
           A P A       R  +        RK+ KP++EK+RRARINESL +L+ L+  A      
Sbjct: 2   APPAAPGRDRVGREDEDGWETRGDRKARKPLVEKKRRARINESLQELRLLLAGA-----E 56

Query: 71  RHSKLEKADILEMTVRHLRSLRRVQVTAALSADPAVLGKYRAGFHECLAEVNRFLAGCEG 130
             +KLE A++LE+TVR ++ + R +             ++ AG+ +C+ EV+ F++ C+ 
Sbjct: 57  VQAKLENAEVLELTVRRVQGVLRGRAREREQLQAEASERFAAGYIQCMHEVHTFVSTCQA 116

Query: 131 VPADVRSRLLGHLAACLRQLGPSRRPASLS----------PAAPAEAPAPEVYAGRPLLP 180
           + A V + LL HL   +    P R  +S            P AP  +  P   A    +P
Sbjct: 117 IDATVAAELLNHLLESM----PLREGSSFQDLLGDALAGPPRAPGRSGWPAGGAPGSPIP 172

Query: 181 SLGGPFPLLAPPLLPGLTRALPAAPRAGP-------------QGPGGPWRPW 219
           S  GP   L   L       L  AP  GP             Q     WRPW
Sbjct: 173 SPPGPGDDLCSDLEEAPEAELSQAPAEGPDLVPAALGSLTTAQIARSVWRPW 224


>gi|105990526 hairy/enhancer-of-split related with YRPW motif 1
           isoform b [Homo sapiens]
          Length = 308

 Score = 87.8 bits (216), Expect = 7e-18
 Identities = 75/201 (37%), Positives = 95/201 (47%), Gaps = 21/201 (10%)

Query: 35  RKSSKPVMEKRRRARINESLAQLKTLILDALRKESSRH--SKLEKADILEMTVRHLRSLR 92
           RK  + ++EKRRR RIN SL++L+ L+  A  K+      +KLEKA+IL+MTV HL+ L 
Sbjct: 50  RKRRRGIIEKRRRDRINNSLSELRRLVPSAFEKQVMEQGSAKLEKAEILQMTVDHLKMLH 109

Query: 93  RVQVTAALSADPAVLGKYRAGFHECLAEVNRFLAGCEGVPAD--VRSRLLGHLAACLRQL 150
                    A    +     GF ECLAEV R+L+  EG+ A   +R RL+ H    L   
Sbjct: 110 TAGGKGYFDAHALAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSH----LNNY 165

Query: 151 GPSRRPASLSPAAPAEAPAPEVYAGRP------LLPSLG-GPFPLLAPPLLP----GLTR 199
              R  AS + A     P   V+   P      LLP  G G     A P  P     L  
Sbjct: 166 ASQREAASGAHAGLGHIPWGTVFGHHPHIAHPLLLPQNGHGNAGTTASPTEPHHQGRLGS 225

Query: 200 ALPAAP--RAGPQGPGGPWRP 218
           A P AP  RA P G  GP  P
Sbjct: 226 AHPEAPALRAPPSGSLGPVLP 246


>gi|6912414 hairy/enhancer-of-split related with YRPW motif 2 [Homo
           sapiens]
          Length = 337

 Score = 86.7 bits (213), Expect = 1e-17
 Identities = 50/128 (39%), Positives = 75/128 (58%), Gaps = 4/128 (3%)

Query: 35  RKSSKPVMEKRRRARINESLAQLKTLILDALRKESSRHSKLEKADILEMTVRHLRSLRRV 94
           RK  + ++EKRRR RIN SL++L+ L+  A  K+ S  +KLEKA+IL+MTV HL+ L+  
Sbjct: 49  RKKRRGIIEKRRRDRINNSLSELRRLVPTAFEKQGS--AKLEKAEILQMTVDHLKMLQAT 106

Query: 95  QVTAALSADPAVLGKYRAGFHECLAEVNRFLAGCEGVPAD--VRSRLLGHLAACLRQLGP 152
                  A    +     GF ECL EV R+L+  EG+ +   +R RL+ HL+ C  Q   
Sbjct: 107 GGKGYFDAHALAMDFMSIGFRECLTEVARYLSSVEGLDSSDPLRVRLVSHLSTCATQREA 166

Query: 153 SRRPASLS 160
           +   +S++
Sbjct: 167 AAMTSSMA 174


>gi|58219048 hairy and enhancer of split 5 [Homo sapiens]
          Length = 166

 Score = 80.1 bits (196), Expect = 1e-15
 Identities = 73/193 (37%), Positives = 91/193 (47%), Gaps = 41/193 (21%)

Query: 30  SAAEHRKSSKPVMEKRRRARINESLAQLKTLILDALRKESSRH---SKLEKADILEMTVR 86
           S  E  +  KPV+EK RR RIN S+ QLK L    L +E +RH   SKLEKADILEM V 
Sbjct: 12  SPKEKNRLRKPVVEKMRRDRINSSIEQLKLL----LEQEFARHQPNSKLEKADILEMAVS 67

Query: 87  HLRSLRRVQVTAALSADPAVLGKYRAGFHECLAEVNRFLAGCEGVPADVRSRLLGHLAAC 146
           +   L+  +   A +   ++   Y  G+  CL E  +FL       +D + +LL H    
Sbjct: 68  Y---LKHSKAFVAAAGPKSLHQDYSEGYSWCLQEAVQFLT--LHAASDTQMKLLYHF--- 119

Query: 147 LRQLGPSRRPASLSPAAPAEAPAPEVYAGRPLLPSLGGPFPLLAPPLLPGLTRALPAAPR 206
                  +RP    PAAPA APA E  A            P  APP  P L+    AA  
Sbjct: 120 -------QRP----PAAPA-APAKEPKA------------PGAAPP--PALSAKATAAAA 153

Query: 207 AGPQGPGGPWRPW 219
           A  Q   G WRPW
Sbjct: 154 AAHQPACGLWRPW 166


>gi|66912172 hairy and enhancer of split 3 [Homo sapiens]
          Length = 186

 Score = 79.3 bits (194), Expect = 2e-15
 Identities = 71/189 (37%), Positives = 95/189 (50%), Gaps = 22/189 (11%)

Query: 42  MEKRRRARINESLAQLKTLILDALRKESSRHSKLEKADILEMTVRHLRSLRRVQVTAALS 101
           MEK+RRARIN SL QLK+L L+       R  KLEKADILE++V+++RSL+     +   
Sbjct: 1   MEKKRRARINVSLEQLKSL-LEKHYSHQIRKRKLEKADILELSVKYMRSLQ----NSLQG 55

Query: 102 ADPAVLG-KYRAGFHECLAEVNRFLAGCEGVPADVRSRLLGHLAA--CLRQLGPSRR-PA 157
             P   G +  +GF  CL  V++ L   + V + +R  L+   AA   +   G  +  PA
Sbjct: 56  LWPVPRGAEQPSGFRSCLPGVSQLLRRGDEVGSGLRCPLVPESAAGSTMDSAGLGQEAPA 115

Query: 158 SLSPAAPAE-APAPEVYAGRPLLPSLGGPFPLLAPPLLPGLTRALPAAPRAGPQGPGGP- 215
              P  PA  APAP   AG P  P    P  LL P  LPG + ++P    A  +    P 
Sbjct: 116 LFRPCTPAVWAPAPA--AGGPRSP----PPLLLLPESLPGSSASVPPPQPASSRCAESPG 169

Query: 216 -----WRPW 219
                WRPW
Sbjct: 170 LGLRVWRPW 178


>gi|13540521 basic helix-loop-helix domain containing, class B, 3
           [Homo sapiens]
          Length = 482

 Score = 62.8 bits (151), Expect = 2e-10
 Identities = 58/186 (31%), Positives = 93/186 (50%), Gaps = 24/186 (12%)

Query: 41  VMEKRRRARINESLAQLKTLILDALRKESSRHSKLEKADILEMTVRHLRSL------RRV 94
           ++EK+RR RINE +AQLK L+ + L+  +  H  LEKA +LE+T++HL++L      +  
Sbjct: 51  LIEKKRRDRINECIAQLKDLLPEHLKLTTLGH--LEKAVVLELTLKHLKALTALTEQQHQ 108

Query: 95  QVTAALSADPAV-------LGKYRAGFHECLAEVNRFLAGCEG-VPADVRS-RLLGHLAA 145
           ++ A  + + ++       L  + +GF  C  EV ++L+  E   P + R  +L+ HL A
Sbjct: 109 KIIALQNGERSLKSPIQSDLDAFHSGFQTCAKEVLQYLSRFESWTPREPRCVQLINHLHA 168

Query: 146 CLRQLGPSRRPASLSPAAPAE----APAPEVYAGRPLLPSLGGPFPLLAPPLLPGLTRAL 201
              Q  P+  P  L+   P      AP+    A  P L   G     LA   +P + R  
Sbjct: 169 VATQFLPT--PQLLTQQVPLSKGTGAPSAAGSAAAPCLERAGQKLEPLA-YCVPVIQRTQ 225

Query: 202 PAAPRA 207
           P+A  A
Sbjct: 226 PSAELA 231


>gi|4503299 basic helix-loop-helix family, member e40 [Homo sapiens]
          Length = 412

 Score = 60.5 bits (145), Expect = 1e-09
 Identities = 55/182 (30%), Positives = 92/182 (50%), Gaps = 32/182 (17%)

Query: 27  KPRSAAEHRKSSKPVMEKRRRARINESLAQLKTLILDALRKESSRHSKLEKADILEMTVR 86
           +   + E  K    ++EK+RR RINE +AQLK L+ + L+  +  H  LEKA +LE+T++
Sbjct: 45  RSEDSKETYKLPHRLIEKKRRDRINECIAQLKDLLPEHLKLTTLGH--LEKAVVLELTLK 102

Query: 87  HLRSL------RRVQVTAALSADPA--VLGK--------YRAGFHECLAEVNRFLAGCEG 130
           H+++L      ++ ++ A  S   A  + G+        + +GF  C  EV ++LA  E 
Sbjct: 103 HVKALTNLIDQQQQKIIALQSGLQAGELSGRNVETGQEMFCSGFQTCAREVLQYLAKHEN 162

Query: 131 VPADVRSRLLGHLAACLRQL---GPSRRPASLSPAAPAEAPAPEV--YAGRPLLPSLGGP 185
                 S+L+ HL   + +L   G SR+P+          PAP+V  +  +P  P+ G  
Sbjct: 163 TRDLKSSQLVTHLHRVVSELLQGGTSRKPSD---------PAPKVMDFKEKPSSPAKGSE 213

Query: 186 FP 187
            P
Sbjct: 214 GP 215


>gi|71274142 HES/HEY-like transcription factor [Homo sapiens]
          Length = 327

 Score = 53.5 bits (127), Expect = 1e-07
 Identities = 70/266 (26%), Positives = 98/266 (36%), Gaps = 74/266 (27%)

Query: 2   AADTPGKPSASPMAGA--PASASRTPDKPRSAAEHRKSSKPVMEKRRRARINESLAQLKT 59
           A+D+P +    PMAG     + S    + R+   H+     V+EKRRR RIN  L +L  
Sbjct: 25  ASDSPTRHLGGPMAGKCPHGTLSVEESRVRTPVSHK-----VIEKRRRDRINRCLNELGK 79

Query: 60  LILDALRKESSRHS---------------------------------------KLEKADI 80
            +  AL K+                                            KLEKA+I
Sbjct: 80  TVPMALAKQGEPQEALAQIRSRVRSLVLSSATVPDQQALGRCEGPFLLLQSSGKLEKAEI 139

Query: 81  LEMTVRHLRSLR-----RVQVTAALSADPAVLGKYRAGFHECLAEVNRFLAGCEGVPADV 135
           LEMTV++LR+L      R +  A L A+ A    +  G+HEC+  +  +L   E +  + 
Sbjct: 140 LEMTVQYLRALHSADFPRGREKAELLAEFA--NYFHYGYHECMKNLVHYLTTVERM--ET 195

Query: 136 RSRLLGHLAACLRQLGPSRRPASLSPAAPAEAPAPE---VYAGRPLLPSLGGPFPLLAPP 192
           +      + A L+    S+      PA P     PE    Y   P  P   G        
Sbjct: 196 KDTKYARILAFLQ----SKARLGAEPAFPPLGSLPEPDFSYQLHPAGPEFAGH------- 244

Query: 193 LLPGLTRALPAAPRAGPQGPGGPWRP 218
             PG     P    AGP     PW P
Sbjct: 245 -SPGEAAVFPQGSGAGP----FPWPP 265


>gi|119703742 vitelliform macular dystrophy 2-like 1 [Homo sapiens]
          Length = 509

 Score = 40.4 bits (93), Expect = 0.001
 Identities = 27/69 (39%), Positives = 29/69 (42%), Gaps = 8/69 (11%)

Query: 157 ASLSPAAPAEAPAPEVYAGRPLLPSLGGPFPLLAPP-------LLPGLTRALPAAPRAGP 209
           AS S A   E  APE   G PLL   G P P   PP       L+PG           GP
Sbjct: 431 ASCSCAVVPEGAAPECSCGDPLLDP-GLPEPEAPPPAGPEPLTLIPGPVEPFSIVTMPGP 489

Query: 210 QGPGGPWRP 218
           +GP  PW P
Sbjct: 490 RGPAPPWLP 498


>gi|9945318 MAX binding protein [Homo sapiens]
          Length = 582

 Score = 39.3 bits (90), Expect = 0.003
 Identities = 24/56 (42%), Positives = 28/56 (50%), Gaps = 5/56 (8%)

Query: 156 PASLSPAAPAEAPAPEVYAGRPL----LPSL-GGPFPLLAPPLLPGLTRALPAAPR 206
           P  LSP AP  AP P +    PL    +P +   P PL  PP LP   + LP APR
Sbjct: 64  PLPLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAAAQPLPLAPR 119



 Score = 31.6 bits (70), Expect = 0.56
 Identities = 25/94 (26%), Positives = 43/94 (45%), Gaps = 7/94 (7%)

Query: 1   MAADTPGKPSASPMAGAPASASRTPD-KPRSAAEHRKSSKPVMEKRRRARINESLAQLKT 59
           +A   P  P+   +  APA   ++ + K R      +     +EK RRA + E    LK 
Sbjct: 186 LAPQQPPPPTLGTLKLAPAEEVKSSEQKKRPGGIGTREVHNKLEKNRRAHLKECFETLKR 245

Query: 60  LILDALRKESSRHSKLEKADILEMTVRHLRSLRR 93
            I +   K++S  S      +L   +R+++SL+R
Sbjct: 246 NIPNVDDKKTSNLS------VLRTALRYIQSLKR 273



 Score = 28.5 bits (62), Expect = 4.7
 Identities = 20/65 (30%), Positives = 25/65 (38%), Gaps = 5/65 (7%)

Query: 154 RRPASLSPAAPAEAPAPEVYAGRPLLPSLGGPFPLLAPPLLPGLTRALPAAPRAGPQGPG 213
           + PA L        PAP +   +  +P  G P PL   P     T  L  AP  G Q   
Sbjct: 132 KEPAPLPSRPQVPTPAPLLPDSKATIPPNGSPKPLQPLP-----TPVLTIAPHPGVQPQL 186

Query: 214 GPWRP 218
            P +P
Sbjct: 187 APQQP 191


>gi|91208437 GEM interacting protein [Homo sapiens]
          Length = 970

 Score = 38.9 bits (89), Expect = 0.004
 Identities = 55/209 (26%), Positives = 78/209 (37%), Gaps = 40/209 (19%)

Query: 22  SRTPDKPRSAAEHRKSSKPVMEKRRRARINESLA---QLKTLILDALRKESSRHSKLEKA 78
           +R+   P  +A          ++RRR    E+ A   + + L    +R+ ++R   LE A
Sbjct: 229 ARSQGSPEDSAPQASPGPSKQQERRRRSREEAQAKAQEAEALYQACVREANARQQDLEIA 288

Query: 79  DILEMTVRHLRSLRRVQVTAALSADPAVLGKYRAGFHECLAEVNRFLAGCEGVPADVRSR 138
              +  V H+R L           D            E L  V   L G  G  A+   R
Sbjct: 289 K--QRIVSHVRKL-------VFQGD------------EVLRRVTLSLFGLRGAQAERGPR 327

Query: 139 LLGHLAACLRQLGPSRR----PASLSPAAPAEAPAPEVYAGRPLLPSLGGPFPL-----L 189
               LA C     P +R      +L P AP   P P  ++ +  LPSL    PL     L
Sbjct: 328 AFAALAECCAPFEPGQRYQEFVRALRPEAP--PPPPPAFSFQEFLPSLNSS-PLDIRKKL 384

Query: 190 APPLLPGLTRALPAAPRAGP-QGPGGPWR 217
           + PL P L      +   GP + PG  WR
Sbjct: 385 SGPLPPRLDE---NSAEPGPWEDPGTGWR 410


>gi|29789008 Huntingtin interacting protein C isoform 2 [Homo
           sapiens]
          Length = 858

 Score = 38.5 bits (88), Expect = 0.005
 Identities = 22/66 (33%), Positives = 32/66 (48%), Gaps = 15/66 (22%)

Query: 153 SRRPASLSPAAPAEAPAPEVYAGRPLLPSLGGPFPL-----LAPPLLPGLTRALPAAPRA 207
           S+RP ++ P  P   P        P+LP +G P PL     + PP++PG+   +PA P  
Sbjct: 19  SQRPPAIPPMPPGILP--------PMLPPMGAPPPLTQIPGMVPPMMPGM--LMPAVPVT 68

Query: 208 GPQGPG 213
               PG
Sbjct: 69  AATAPG 74


>gi|72534686 Huntingtin interacting protein C isoform 1 [Homo
           sapiens]
          Length = 871

 Score = 38.5 bits (88), Expect = 0.005
 Identities = 22/66 (33%), Positives = 32/66 (48%), Gaps = 15/66 (22%)

Query: 153 SRRPASLSPAAPAEAPAPEVYAGRPLLPSLGGPFPL-----LAPPLLPGLTRALPAAPRA 207
           S+RP ++ P  P   P        P+LP +G P PL     + PP++PG+   +PA P  
Sbjct: 25  SQRPPAIPPMPPGILP--------PMLPPMGAPPPLTQIPGMVPPMMPGM--LMPAVPVT 74

Query: 208 GPQGPG 213
               PG
Sbjct: 75  AATAPG 80


>gi|192807323 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a4 isoform A [Homo sapiens]
          Length = 1679

 Score = 38.1 bits (87), Expect = 0.006
 Identities = 36/134 (26%), Positives = 55/134 (41%), Gaps = 22/134 (16%)

Query: 102 ADPAVLGKYRAG--------FHECLAEVNRF--LAGCEGVPADVRSRLLGHLAAC-LRQL 150
           ADP  LG+   G         H+  A++  +  LA  + +P  ++  + G      ++Q 
Sbjct: 157 ADPQALGQQNRGPTPFNQNQLHQLRAQIMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQ 216

Query: 151 GPSRRPASLSPAAPAEAPAPEVYAGR-PLLPSLGGPF----PLLAPPLLPGLTRALPAAP 205
            P+  P S+S   P   P P    G  P  P+   P     P + PP   G+   +P  P
Sbjct: 217 MPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQP 276

Query: 206 RAGPQGPGGPWRPW 219
                 PGGP +PW
Sbjct: 277 ------PGGPPKPW 284


>gi|192807320 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a4 isoform F [Homo sapiens]
          Length = 1613

 Score = 38.1 bits (87), Expect = 0.006
 Identities = 36/134 (26%), Positives = 55/134 (41%), Gaps = 22/134 (16%)

Query: 102 ADPAVLGKYRAG--------FHECLAEVNRF--LAGCEGVPADVRSRLLGHLAAC-LRQL 150
           ADP  LG+   G         H+  A++  +  LA  + +P  ++  + G      ++Q 
Sbjct: 157 ADPQALGQQNRGPTPFNQNQLHQLRAQIMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQ 216

Query: 151 GPSRRPASLSPAAPAEAPAPEVYAGR-PLLPSLGGPF----PLLAPPLLPGLTRALPAAP 205
            P+  P S+S   P   P P    G  P  P+   P     P + PP   G+   +P  P
Sbjct: 217 MPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQP 276

Query: 206 RAGPQGPGGPWRPW 219
                 PGGP +PW
Sbjct: 277 ------PGGPPKPW 284


>gi|192807318 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a4 isoform E [Homo sapiens]
          Length = 1614

 Score = 38.1 bits (87), Expect = 0.006
 Identities = 36/134 (26%), Positives = 55/134 (41%), Gaps = 22/134 (16%)

Query: 102 ADPAVLGKYRAG--------FHECLAEVNRF--LAGCEGVPADVRSRLLGHLAAC-LRQL 150
           ADP  LG+   G         H+  A++  +  LA  + +P  ++  + G      ++Q 
Sbjct: 157 ADPQALGQQNRGPTPFNQNQLHQLRAQIMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQ 216

Query: 151 GPSRRPASLSPAAPAEAPAPEVYAGR-PLLPSLGGPF----PLLAPPLLPGLTRALPAAP 205
            P+  P S+S   P   P P    G  P  P+   P     P + PP   G+   +P  P
Sbjct: 217 MPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQP 276

Query: 206 RAGPQGPGGPWRPW 219
                 PGGP +PW
Sbjct: 277 ------PGGPPKPW 284


>gi|192807316 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a4 isoform D [Homo sapiens]
          Length = 1616

 Score = 38.1 bits (87), Expect = 0.006
 Identities = 36/134 (26%), Positives = 55/134 (41%), Gaps = 22/134 (16%)

Query: 102 ADPAVLGKYRAG--------FHECLAEVNRF--LAGCEGVPADVRSRLLGHLAAC-LRQL 150
           ADP  LG+   G         H+  A++  +  LA  + +P  ++  + G      ++Q 
Sbjct: 157 ADPQALGQQNRGPTPFNQNQLHQLRAQIMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQ 216

Query: 151 GPSRRPASLSPAAPAEAPAPEVYAGR-PLLPSLGGPF----PLLAPPLLPGLTRALPAAP 205
            P+  P S+S   P   P P    G  P  P+   P     P + PP   G+   +P  P
Sbjct: 217 MPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQP 276

Query: 206 RAGPQGPGGPWRPW 219
                 PGGP +PW
Sbjct: 277 ------PGGPPKPW 284


>gi|192807314 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a4 isoform C [Homo sapiens]
          Length = 1617

 Score = 38.1 bits (87), Expect = 0.006
 Identities = 36/134 (26%), Positives = 55/134 (41%), Gaps = 22/134 (16%)

Query: 102 ADPAVLGKYRAG--------FHECLAEVNRF--LAGCEGVPADVRSRLLGHLAAC-LRQL 150
           ADP  LG+   G         H+  A++  +  LA  + +P  ++  + G      ++Q 
Sbjct: 157 ADPQALGQQNRGPTPFNQNQLHQLRAQIMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQ 216

Query: 151 GPSRRPASLSPAAPAEAPAPEVYAGR-PLLPSLGGPF----PLLAPPLLPGLTRALPAAP 205
            P+  P S+S   P   P P    G  P  P+   P     P + PP   G+   +P  P
Sbjct: 217 MPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQP 276

Query: 206 RAGPQGPGGPWRPW 219
                 PGGP +PW
Sbjct: 277 ------PGGPPKPW 284


>gi|192807312 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a4 isoform B [Homo sapiens]
          Length = 1647

 Score = 38.1 bits (87), Expect = 0.006
 Identities = 36/134 (26%), Positives = 55/134 (41%), Gaps = 22/134 (16%)

Query: 102 ADPAVLGKYRAG--------FHECLAEVNRF--LAGCEGVPADVRSRLLGHLAAC-LRQL 150
           ADP  LG+   G         H+  A++  +  LA  + +P  ++  + G      ++Q 
Sbjct: 157 ADPQALGQQNRGPTPFNQNQLHQLRAQIMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQ 216

Query: 151 GPSRRPASLSPAAPAEAPAPEVYAGR-PLLPSLGGPF----PLLAPPLLPGLTRALPAAP 205
            P+  P S+S   P   P P    G  P  P+   P     P + PP   G+   +P  P
Sbjct: 217 MPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQP 276

Query: 206 RAGPQGPGGPWRPW 219
                 PGGP +PW
Sbjct: 277 ------PGGPPKPW 284


>gi|21071056 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a4 isoform B [Homo sapiens]
          Length = 1647

 Score = 38.1 bits (87), Expect = 0.006
 Identities = 36/134 (26%), Positives = 55/134 (41%), Gaps = 22/134 (16%)

Query: 102 ADPAVLGKYRAG--------FHECLAEVNRF--LAGCEGVPADVRSRLLGHLAAC-LRQL 150
           ADP  LG+   G         H+  A++  +  LA  + +P  ++  + G      ++Q 
Sbjct: 157 ADPQALGQQNRGPTPFNQNQLHQLRAQIMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQ 216

Query: 151 GPSRRPASLSPAAPAEAPAPEVYAGR-PLLPSLGGPF----PLLAPPLLPGLTRALPAAP 205
            P+  P S+S   P   P P    G  P  P+   P     P + PP   G+   +P  P
Sbjct: 217 MPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQP 276

Query: 206 RAGPQGPGGPWRPW 219
                 PGGP +PW
Sbjct: 277 ------PGGPPKPW 284


>gi|148613882 homeobox A4 [Homo sapiens]
          Length = 320

 Score = 38.1 bits (87), Expect = 0.006
 Identities = 26/70 (37%), Positives = 29/70 (41%), Gaps = 2/70 (2%)

Query: 152 PSRRPASLSPAAPAEAPAPEVYAGRPLLPSLGGPF-PLLAPPLLPGLTRALPAAPRAGPQ 210
           P R P    P A A+ PA  ++A   L P L  P  P   PP  P    A PA P   P 
Sbjct: 110 PGRPPQPEQPPAQAKGPAHGLHASHVLQPQLPPPLQPRAVPPAAPRRCEAAPATPGV-PA 168

Query: 211 GPGGPWRPWL 220
           G   P  P L
Sbjct: 169 GGSAPACPLL 178


>gi|59853099 dynamin 1 isoform 1 [Homo sapiens]
          Length = 864

 Score = 38.1 bits (87), Expect = 0.006
 Identities = 33/94 (35%), Positives = 37/94 (39%), Gaps = 5/94 (5%)

Query: 129 EGVPADVRSRLLGHLAACLRQLGPSRRPASLSPAAPAEAPAPEVYAGRPLLPSLGG--PF 186
           + VPA  RS              P  RP S  PA P   PA     G P +PS  G  P 
Sbjct: 766 QSVPAGRRSPTSSPTPQRRAPAVPPARPGSRGPA-PGPPPAGSALGGAPPVPSRPGASPD 824

Query: 187 PLLAPPLLPGL-TRALPAAP-RAGPQGPGGPWRP 218
           P   PP +P    RA P  P R+G   P  P  P
Sbjct: 825 PFGPPPQVPSRPNRAPPGVPSRSGQASPSRPESP 858


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.133    0.400 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,288,173
Number of Sequences: 37866
Number of extensions: 603787
Number of successful extensions: 7050
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 129
Number of HSP's successfully gapped in prelim test: 487
Number of HSP's that attempted gapping in prelim test: 5570
Number of HSP's gapped (non-prelim): 1931
length of query: 221
length of database: 18,247,518
effective HSP length: 98
effective length of query: 123
effective length of database: 14,536,650
effective search space: 1788007950
effective search space used: 1788007950
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.