BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|10863879 solute carrier family 5 (sodium-dependent vitamin transporter), member 6 [Homo sapiens] (635 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|10863879 solute carrier family 5 (sodium-dependent vitamin tr... 1268 0.0 gi|167466278 solute carrier family 5 (iodide transporter), membe... 502 e-142 gi|157671931 solute carrier family 5 (sodium/glucose cotransport... 481 e-136 gi|4507035 solute carrier family 5 (sodium iodide symporter), me... 444 e-124 gi|109659836 solute carrier family 5 (sodium/glucose cotransport... 136 5e-32 gi|109659839 solute carrier family 5 (sodium/glucose cotransport... 134 2e-31 gi|17941285 solute carrier family 5 (sodium/glucose cotransporte... 119 6e-27 gi|4507031 solute carrier family 5 (sodium/glucose cotransporter... 119 1e-26 gi|14140236 solute carrier family 5 (low affinity glucose cotran... 115 1e-25 gi|206597483 solute carrier family 5 (sodium/glucose cotransport... 107 3e-23 gi|4507033 solute carrier family 5 (sodium/glucose cotransporter... 99 9e-21 gi|206597487 solute carrier family 5 (sodium/glucose cotransport... 99 2e-20 gi|110835708 solute carrier family 5 (inositol transporters), me... 89 9e-18 gi|11141885 solute carrier family 5 (choline transporter), membe... 58 2e-08 gi|21361423 solute carrier family 39 (zinc transporter), member ... 35 0.16 gi|28872803 myeloid translocation gene on chromosome 16 isoform ... 33 1.0 gi|28872805 myeloid translocation gene on chromosome 16 isoform ... 33 1.0 gi|40354205 aldolase B, fructose-bisphosphate [Homo sapiens] 32 1.8 gi|45580709 unc-93 homolog B1 [Homo sapiens] 32 1.8 gi|28329422 acute myelogenous leukemia 1 translocation 1 protein... 31 3.0 gi|28329419 acute myelogenous leukemia 1 translocation 1 protein... 31 3.0 gi|28329416 acute myelogenous leukemia 1 translocation 1 protein... 31 3.0 gi|4757916 acute myelogenous leukemia 1 translocation 1 protein ... 31 3.0 gi|31543630 solute carrier family 20 (phosphate transporter), me... 31 3.0 gi|225579067 solute carrier family 12, member 4 isoform e [Homo ... 31 4.0 gi|225579065 solute carrier family 12, member 4 isoform d [Homo ... 31 4.0 gi|225579063 solute carrier family 12, member 4 isoform c [Homo ... 31 4.0 gi|225579061 solute carrier family 12, member 4 isoform b [Homo ... 31 4.0 gi|4827006 solute carrier family 12, member 4 isoform a [Homo sa... 31 4.0 gi|62912479 major histocompatibility complex, class I, E precurs... 30 8.8 >gi|10863879 solute carrier family 5 (sodium-dependent vitamin transporter), member 6 [Homo sapiens] Length = 635 Score = 1268 bits (3280), Expect = 0.0 Identities = 635/635 (100%), Positives = 635/635 (100%) Query: 1 MSVGVSTSAPLSPTSGTSVGMSTFSIMDYVVFVLLLVLSLAIGLYHACRGWGRHTVGELL 60 MSVGVSTSAPLSPTSGTSVGMSTFSIMDYVVFVLLLVLSLAIGLYHACRGWGRHTVGELL Sbjct: 1 MSVGVSTSAPLSPTSGTSVGMSTFSIMDYVVFVLLLVLSLAIGLYHACRGWGRHTVGELL 60 Query: 61 MADRKMGCLPVALSLLATFQSAVAILGVPSEIYRFGTQYWFLGCCYFLGLLIPAHIFIPV 120 MADRKMGCLPVALSLLATFQSAVAILGVPSEIYRFGTQYWFLGCCYFLGLLIPAHIFIPV Sbjct: 61 MADRKMGCLPVALSLLATFQSAVAILGVPSEIYRFGTQYWFLGCCYFLGLLIPAHIFIPV 120 Query: 121 FYRLHLTSAYEYLELRFNKTVRVCGTVTFIFQMVIYMGVVLYAPSLALNAVTGFDLWLSV 180 FYRLHLTSAYEYLELRFNKTVRVCGTVTFIFQMVIYMGVVLYAPSLALNAVTGFDLWLSV Sbjct: 121 FYRLHLTSAYEYLELRFNKTVRVCGTVTFIFQMVIYMGVVLYAPSLALNAVTGFDLWLSV 180 Query: 181 LALGIVCTVYTALGGLKAVIWTDVFQTLVMFLGQLAVIIVGSAKVGGLGRVWAVASQHGR 240 LALGIVCTVYTALGGLKAVIWTDVFQTLVMFLGQLAVIIVGSAKVGGLGRVWAVASQHGR Sbjct: 181 LALGIVCTVYTALGGLKAVIWTDVFQTLVMFLGQLAVIIVGSAKVGGLGRVWAVASQHGR 240 Query: 241 ISGFELDPDPFVRHTFWTLAFGGVFMMLSLYGVNQAQVQRYLSSRTEKAAVLSCYAVFPF 300 ISGFELDPDPFVRHTFWTLAFGGVFMMLSLYGVNQAQVQRYLSSRTEKAAVLSCYAVFPF Sbjct: 241 ISGFELDPDPFVRHTFWTLAFGGVFMMLSLYGVNQAQVQRYLSSRTEKAAVLSCYAVFPF 300 Query: 301 QQVSLCVGCLIGLVMFAYYQEYPMSIQQAQAAPDQFVLYFVMDLLKGLPGLPGLFIACLF 360 QQVSLCVGCLIGLVMFAYYQEYPMSIQQAQAAPDQFVLYFVMDLLKGLPGLPGLFIACLF Sbjct: 301 QQVSLCVGCLIGLVMFAYYQEYPMSIQQAQAAPDQFVLYFVMDLLKGLPGLPGLFIACLF 360 Query: 361 SGSLSTISSAFNSLATVTMEDLIRPWFPEFSEARAIMLSRGLAFGYGLLCLGMAYISSQM 420 SGSLSTISSAFNSLATVTMEDLIRPWFPEFSEARAIMLSRGLAFGYGLLCLGMAYISSQM Sbjct: 361 SGSLSTISSAFNSLATVTMEDLIRPWFPEFSEARAIMLSRGLAFGYGLLCLGMAYISSQM 420 Query: 421 GPVLQAAISIFGMVGGPLLGLFCLGMFFPCANPPGAVVGLLAGLVMAFWIGIGSIVTSMG 480 GPVLQAAISIFGMVGGPLLGLFCLGMFFPCANPPGAVVGLLAGLVMAFWIGIGSIVTSMG Sbjct: 421 GPVLQAAISIFGMVGGPLLGLFCLGMFFPCANPPGAVVGLLAGLVMAFWIGIGSIVTSMG 480 Query: 481 FSMPPSPSNGSSFSLPTNLTVATVTTLMPLTTFSKPTGLQRFYSLSYLWYSAHNSTTVIV 540 FSMPPSPSNGSSFSLPTNLTVATVTTLMPLTTFSKPTGLQRFYSLSYLWYSAHNSTTVIV Sbjct: 481 FSMPPSPSNGSSFSLPTNLTVATVTTLMPLTTFSKPTGLQRFYSLSYLWYSAHNSTTVIV 540 Query: 541 VGLIVSLLTGRMRGRSLNPATIYPVLPKLLSLLPLSCQKRLHCRSYGQDHLDTGLFPEKP 600 VGLIVSLLTGRMRGRSLNPATIYPVLPKLLSLLPLSCQKRLHCRSYGQDHLDTGLFPEKP Sbjct: 541 VGLIVSLLTGRMRGRSLNPATIYPVLPKLLSLLPLSCQKRLHCRSYGQDHLDTGLFPEKP 600 Query: 601 RNGVLGDSRDKEAMALDGTAYQGSSSTCILQETSL 635 RNGVLGDSRDKEAMALDGTAYQGSSSTCILQETSL Sbjct: 601 RNGVLGDSRDKEAMALDGTAYQGSSSTCILQETSL 635 >gi|167466278 solute carrier family 5 (iodide transporter), member 8 [Homo sapiens] Length = 610 Score = 502 bits (1293), Expect = e-142 Identities = 265/560 (47%), Positives = 360/560 (64%), Gaps = 21/560 (3%) Query: 17 TSVGMSTFSIMDYVVFVLLLVLSLAIGLYHACRGWGRHTVGELLMADRKMGCLPVALSLL 76 T G+ TF + DYVVF +LV+S AIG+Y+A G G+ T + LM R+M +PVALSL Sbjct: 3 TPRGIGTFVVWDYVVFAGMLVISAAIGIYYAFAGGGQQTSKDFLMGGRRMTAVPVALSLT 62 Query: 77 ATFQSAVAILGVPSEIYRFGTQYWFLGCCYFLGLLIPAHIFIPVFYRLHLTSAYEYLELR 136 A+F SAV +LG PSE+YRFG + YF ++I A +F+PVFY+L +TS YEYLELR Sbjct: 63 ASFMSAVTVLGTPSEVYRFGAIFSIFAFTYFFVVVISAEVFLPVFYKLGITSTYEYLELR 122 Query: 137 FNKTVRVCGTVTFIFQMVIYMGVVLYAPSLALNAVTGFDLWLSVLALGIVCTVYTALGGL 196 FNK VR+CGTV FI Q ++Y G+V+YAP+LALN VTGFDLW +V+A G+VCT Y LGGL Sbjct: 123 FNKCVRLCGTVLFIVQTILYTGIVIYAPALALNQVTGFDLWGAVVATGVVCTFYCTLGGL 182 Query: 197 KAVIWTDVFQTLVMFLGQLAVIIVGSAKVGGLGRVWAVASQHGRISGFELDPDPFVRHTF 256 KAVIWTDVFQ +M G +VII GG+ + A GR++ + +P+P RHTF Sbjct: 183 KAVIWTDVFQVGIMVAGFASVIIQAVVMQGGISTILNDAYDGGRLNFWNFNPNPLQRHTF 242 Query: 257 WTLAFGGVFMMLSLYGVNQAQVQRYLSSRTEKAAVLSCYAVFPFQQVSLCVGCLIGLVMF 316 WT+ GG F S+YGVNQ+QVQRY+S ++ A LS Y L GL ++ Sbjct: 243 WTIIIGGTFTWTSIYGVNQSQVQRYISCKSRFQAKLSLYINLVGLWAILTCSVFCGLALY 302 Query: 317 AYYQEYPMSIQQAQAAPDQFVLYFVMDLLKGLPGLPGLFIACLFSGSLSTISSAFNSLAT 376 + Y + + +APDQ + Y V+D+L+ PGLPGLF+AC +SG+LST+SS+ N+LA Sbjct: 303 SRYHDCDPWTAKKVSAPDQLMPYLVLDILQDYPGLPGLFVACAYSGTLSTVSSSINALAA 362 Query: 377 VTMEDLIRPWFPEFSEARAIMLSRGLAFGYGLLCLGMAYISSQMGPVLQAAISIFGMVGG 436 VT+EDLI+P+F SE +S+G++ YG LC+GMA ++S MG +LQAA+S+FGMVGG Sbjct: 363 VTVEDLIKPYFRSLSERSLSWISQGMSVVYGALCIGMAALASLMGALLQAALSVFGMVGG 422 Query: 437 PLLGLFCLGMFFPCANPPGAVVGLLAGLVMAFWIGIGSIVTSMGFSMPPSPSNGSSFSLP 496 PL+GLF LG+ P AN GA+VGL+AG ++ W+GIG+ + PP P L Sbjct: 423 PLMGLFALGILVPFANSIGALVGLMAGFAISLWVGIGAQI------YPPLPERTLPLHLD 476 Query: 497 T-------NLTVATVTTLMPLTT-------FSKPTGLQRFYSLSYLWYSAHNSTTVIVVG 542 N T TT MP TT + + +YSLSYL++S + ++VG Sbjct: 477 IQGCNSTYNETNLMTTTEMPFTTSVFQIYNVQRTPLMDNWYSLSYLYFSTVGTLVTLLVG 536 Query: 543 LIVSLLTGRMRGRSLNPATI 562 ++VSL TG R ++L+P I Sbjct: 537 ILVSLSTGG-RKQNLDPRYI 555 >gi|157671931 solute carrier family 5 (sodium/glucose cotransporter), member 12 [Homo sapiens] Length = 618 Score = 481 bits (1238), Expect = e-136 Identities = 250/546 (45%), Positives = 342/546 (62%), Gaps = 7/546 (1%) Query: 21 MSTFSIMDYVVFVLLLVLSLAIGLYHACRGWGRHTVGELLMADRKMGCLPVALSLLATFQ 80 + F++ DYVVF L +S IG++ A + + T E L+ R+M PV LSL A+F Sbjct: 3 VKNFAVWDYVVFAALFFISSGIGVFFAIKERKKATSREFLVGGRQMSFGPVGLSLTASFM 62 Query: 81 SAVAILGVPSEIYRFGTQYWFLGCCYFLGLLIPAHIFIPVFYRLHLTSAYEYLELRFNKT 140 SAV +LG PSE+YRFG + Y +L+ + +F+PVFYR +TS YEYL+LRFNK Sbjct: 63 SAVTVLGTPSEVYRFGASFLVFFIAYLFVILLTSELFLPVFYRSGITSTYEYLQLRFNKP 122 Query: 141 VRVCGTVTFIFQMVIYMGVVLYAPSLALNAVTGFDLWLSVLALGIVCTVYTALGGLKAVI 200 VR TV +I Q ++Y GVV+YAP+LALN VTGFDLW SV A GIVCT Y LGGLKAV+ Sbjct: 123 VRYAATVIYIVQTILYTGVVVYAPALALNQVTGFDLWGSVFATGIVCTFYCTLGGLKAVV 182 Query: 201 WTDVFQTLVMFLGQLAVIIVGSAKVGGLGRVWAVASQHGRISGFELDPDPFVRHTFWTLA 260 WTD FQ +VM +G L V+I GS GG V ++ R+ F+ D DP RHTFWT+ Sbjct: 183 WTDAFQMVVMIVGFLTVLIQGSTHAGGFHNVLEQSTNGSRLHIFDFDVDPLRRHTFWTIT 242 Query: 261 FGGVFMMLSLYGVNQAQVQRYLSSRTEKAAVLSCYAVFPFQQVSLCVGCLIGLVMFAYYQ 320 GG F L +YGVNQ+ +QR +S +TEK A L+ Y + L GL+M+++++ Sbjct: 243 VGGTFTWLGIYGVNQSTIQRCISCKTEKHAKLALYFNLLGLWIILVCAVFSGLIMYSHFK 302 Query: 321 EYPMSIQQAQAAPDQFVLYFVMDLLKGLPGLPGLFIACLFSGSLSTISSAFNSLATVTME 380 + +APDQ + YFVM++ +PGLPGLF+AC FSG+LST++S+ N+LATVT E Sbjct: 303 DCDPWTSGIISAPDQLMPYFVMEIFATMPGLPGLFVACAFSGTLSTVASSINALATVTFE 362 Query: 381 DLIRPWFPEFSEARAIMLSRGLAFGYGLLCLGMAYISSQMGPVLQAAISIFGMVGGPLLG 440 D ++ FP S+ + +S+GL +G++C MA +S MG V+QA++SI GM GGP+LG Sbjct: 363 DFVKSCFPHLSDKLSTWISKGLCLLFGVMCTSMAVAASVMGGVVQASLSIHGMCGGPMLG 422 Query: 441 LFCLGMFFPCANPPGAVVGLLAGLVMAFWIGIGSIVTSMGFSMPPSPSNGSSFSLPTNLT 500 LF LG+ FP N GA+ GLL G+ ++FW+ IG+ F P S L T+ Sbjct: 423 LFSLGIVFPFVNWKGALGGLLTGITLSFWVAIGA------FIYPAPASKTWPLPLSTDQC 476 Query: 501 V-ATVTTLMPLTTFSKPTGLQRFYSLSYLWYSAHNSTTVIVVGLIVSLLTGRMRGRSLNP 559 + + VT P S+P +YS+SYL+YSA IV G+I+SL+TGR RG + P Sbjct: 477 IKSNVTATGPPVLSSRPGIADTWYSISYLYYSAVGCLGCIVAGVIISLITGRQRGEDIQP 536 Query: 560 ATIYPV 565 I PV Sbjct: 537 LLIRPV 542 >gi|4507035 solute carrier family 5 (sodium iodide symporter), member 5 [Homo sapiens] Length = 643 Score = 444 bits (1141), Expect = e-124 Identities = 237/562 (42%), Positives = 348/562 (61%), Gaps = 29/562 (5%) Query: 23 TFSIMDYVVFVLLLVLSLAIGLYHACRGWGRHTVGELLMADRKMGCLPVALSLLATFQSA 82 TF DY VF L+L++S IGL+ G+ + + R++ LPV LSL A+F SA Sbjct: 11 TFGAWDYGVFALMLLVSTGIGLWVGLARGGQRSAEDFFTGGRRLAALPVGLSLSASFMSA 70 Query: 83 VAILGVPSEIYRFGTQYWFLGCCYFLGLLIPAHIFIPVFYRLHLTSAYEYLELRFNKTVR 142 V +LGVPSE YR+G ++ ++ L ++ A +F+PVFYRL LTS YEYLE+RF++ VR Sbjct: 71 VQVLGVPSEAYRYGLKFLWMCLGQLLNSVLTALLFMPVFYRLGLTSTYEYLEMRFSRAVR 130 Query: 143 VCGTVTFIFQMVIYMGVVLYAPSLALNAVTGFDLWLSVLALGIVCTVYTALGGLKAVIWT 202 +CGT+ +I ++Y G+V+YAP+L LN VTG D+W S+L+ GI+CT YTA+GG+KAV+WT Sbjct: 131 LCGTLQYIVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTFYTAVGGMKAVVWT 190 Query: 203 DVFQTLVMFLGQLAVIIVGSAKVGGLGRVWAVASQHGRISGFELDPDPFVRHTFWTLAFG 262 DVFQ +VM G V+ G VGG +V +A H RI+ + +PDP R+TFWT G Sbjct: 191 DVFQVVVMLSGFWVVLARGVMLVGGPRQVLTLAQNHSRINLMDFNPDPRSRYTFWTFVVG 250 Query: 263 GVFMMLSLYGVNQAQVQRYLSSRTEKAAVLSCY--AVFPFQQVSLCVGCLIGLVMFAYYQ 320 G + LS+YGVNQAQVQRY++ RTEK A L+ V F VS C G+VMF +Y Sbjct: 251 GTLVWLSMYGVNQAQVQRYVACRTEKQAKLALLINQVGLFLIVSSAACC--GIVMFVFYT 308 Query: 321 EYPMSIQQAQAAPDQFVLYFVMDLLKGLPGLPGLFIACLFSGSLSTISSAFNSLATVTME 380 + + +APDQ++ V+D+ + LPG+PGLF+AC +SG+LST S++ N++A VT+E Sbjct: 309 DCDPLLLGRISAPDQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTASTSINAMAAVTVE 368 Query: 381 DLIRPWFPEFSEARAIMLSRGLAFGYGLLCLGMAYISSQM-GPVLQAAISIFGMVGGPLL 439 DLI+P + + +++S+GL+ YG CL +A +SS + G VLQ + ++ G++ GPLL Sbjct: 369 DLIKPRLRSLAPRKLVIISKGLSLIYGSACLTVAALSSLLGGGVLQGSFTVMGVISGPLL 428 Query: 440 GLFCLGMFFPCANPPGAVVGLLAGLVMAFWIGIGSIVTSMGFSMPPS-------PSNGS- 491 G F LGMF P N PG + GL AGL ++ W+ +G+ + PPS PS+ + Sbjct: 429 GAFILGMFLPACNTPGVLAGLGAGLALSLWVALGATL------YPPSEQTMRVLPSSAAR 482 Query: 492 SFSLPTNLTVATVTTLMPLT----------TFSKPTGLQRFYSLSYLWYSAHNSTTVIVV 541 +L N + L+P S+P FY++SYL+Y A + T ++ Sbjct: 483 CVALSVNASGLLDPALLPANDSSRAPSSGMDASRPALADSFYAISYLYYGALGTLTTVLC 542 Query: 542 GLIVSLLTGRMRGRSLNPATIY 563 G ++S LTG + +L P ++ Sbjct: 543 GALISCLTGPTKRSTLAPGLLW 564 >gi|109659836 solute carrier family 5 (sodium/glucose cotransporter), member 10 isoform 2 [Homo sapiens] Length = 596 Score = 136 bits (343), Expect = 5e-32 Identities = 126/483 (26%), Positives = 224/483 (46%), Gaps = 36/483 (7%) Query: 14 TSGTSVGMSTFSIMDYVVFVLLLVLSLAIGLYHACRGWGRHTVGELLMADRKMGCLPVAL 73 TS + S+ D +V + L++A+G++ +CR R+TV +A R M P+ Sbjct: 6 TSDLHTPGTQLSVADIIVITVYFALNVAVGIWSSCRA-SRNTVNGYFLAGRDMTWWPIGA 64 Query: 74 SLLATFQSAVAILGVPSEIYRFGTQYWFLGCCYFLGLLIPAHIFIPVFYRLHLTSAYEYL 133 SL A+ + + +G+ G LL A +F+P++ + + EY+ Sbjct: 65 SLFASSEGSGLFIGLAGSGAAGGLAVAGFEWNATYVLLALAWVFVPIYISSEIVTLPEYI 124 Query: 134 ELRFN-KTVRV-CGTVTFIFQMVIYMGVVLYAPSLALNAVTGFDLWLS-VLALGIVCTVY 190 + R+ + +R+ ++ + + + + LYA +L ++ G++ +LS +L LGI +Y Sbjct: 125 QKRYGGQRIRMYLSVLSLLLSVFTKISLDLYAGALFVHICLGWNFYLSTILTLGITA-LY 183 Query: 191 TALGGLKAVIWTDVFQTLVMFLGQLAVIIVGSAKVGGLGRVWAVASQH------------ 238 T GGL AVI+TD QTL+M +G + + I ++GG G++ A +Q Sbjct: 184 TIAGGLAAVIYTDALQTLIMVVGAVILTIKAFDQIGGYGQLEAAYAQAIPSRTIANTTCH 243 Query: 239 -GRISGFELDPDPFVRHTFWT-LAFGGVFMMLSLYGVNQAQVQRYLSSRTEKAAVLSCYA 296 R + DP WT + FG M + +Q VQR LS+R A Sbjct: 244 LPRTDAMHMFRDPHTGDLPWTGMTFGLTIMATWYWCTDQVIVQRSLSARDLNHAKAGSIL 303 Query: 297 VFPFQQVSLCVGCLIGLVMFAYYQE-----YPMSIQQAQAAP--DQFVLY--FVMDLLKG 347 + + + + + G++ A + + P +A A + Y VM+L+ Sbjct: 304 ASYLKMLPMGLIIMPGMISRALFPDDVGCVVPSECLRACGAEVGCSNIAYPKLVMELMP- 362 Query: 348 LPGLPGLFIACLFSGSLSTISSAFNSLATVTMEDLIRPWFPEFSEARAIMLSRGLAFGYG 407 GL GL IA + + +S+++S FNS +T+ D+ R P E +++ R + Sbjct: 363 -IGLRGLMIAVMLAALMSSLTSIFNSSSTLFTMDIWRRLRPRSGERELLLVGRLVI--VA 419 Query: 408 LLCLGMAYI----SSQMGPVLQAAISIFGMVGGPLLGLFCLGMFFPCANPPGAVVGLLAG 463 L+ + +A+I S G + S+ + P+ +F LG+F+ AN GA GL+AG Sbjct: 420 LIGVSVAWIPVLQDSNSGQLFIYMQSVTSSLAPPVTAVFVLGVFWRRANEQGAFWGLIAG 479 Query: 464 LVM 466 LV+ Sbjct: 480 LVV 482 >gi|109659839 solute carrier family 5 (sodium/glucose cotransporter), member 10 isoform 1 [Homo sapiens] Length = 612 Score = 134 bits (338), Expect = 2e-31 Identities = 128/500 (25%), Positives = 230/500 (46%), Gaps = 54/500 (10%) Query: 14 TSGTSVGMSTFSIMDYVVFVLLLVLSLAIGLYHACRGWGRHTVGELLMADRKMGCLPVAL 73 TS + S+ D +V + L++A+G++ +CR R+TV +A R M P+ Sbjct: 6 TSDLHTPGTQLSVADIIVITVYFALNVAVGIWSSCRA-SRNTVNGYFLAGRDMTWWPIGA 64 Query: 74 SLLATFQSAVAILGVPSEIYRFGTQYWFLGCCYFLGLLIPAHIFIPVFYRLHLTSAYEYL 133 SL A+ + + +G+ G LL A +F+P++ + + EY+ Sbjct: 65 SLFASSEGSGLFIGLAGSGAAGGLAVAGFEWNATYVLLALAWVFVPIYISSEIVTLPEYI 124 Query: 134 ELRFN-KTVRV-CGTVTFIFQMVIYMGVVLYAPSLALNAVTGFDLWLS-VLALGIVCTVY 190 + R+ + +R+ ++ + + + + LYA +L ++ G++ +LS +L LGI +Y Sbjct: 125 QKRYGGQRIRMYLSVLSLLLSVFTKISLDLYAGALFVHICLGWNFYLSTILTLGITA-LY 183 Query: 191 TALGGLKAVIWTDVFQTLVMFLGQLAVIIVGSAKVGGLGRVWAVASQH------------ 238 T GGL AVI+TD QTL+M +G + + I ++GG G++ A +Q Sbjct: 184 TIAGGLAAVIYTDALQTLIMVVGAVILTIKAFDQIGGYGQLEAAYAQAIPSRTIANTTCH 243 Query: 239 -GRISGFELDPDPFVRHTFWT-LAFGGVFMMLSLYGVNQAQVQRYLSSR----TEKAAVL 292 R + DP WT + FG M + +Q VQR LS+R + ++L Sbjct: 244 LPRTDAMHMFRDPHTGDLPWTGMTFGLTIMATWYWCTDQVIVQRSLSARDLNHAKAGSIL 303 Query: 293 SCYAVFPFQQVSLCVGCLIGLVMF----AYYQEYPMSIQQAQ----AAPDQF-------- 336 + Y + + G +I +F Y + + +S+ + P + Sbjct: 304 ASYLKMLPMGLIIMPG-MISRALFPGAHVYEERHQVSVSRTDDVGCVVPSECLRACGAEV 362 Query: 337 ----VLY--FVMDLLKGLPGLPGLFIACLFSGSLSTISSAFNSLATVTMEDLIRPWFPEF 390 + Y VM+L+ GL GL IA + + +S+++S FNS +T+ D+ R P Sbjct: 363 GCSNIAYPKLVMELMP--IGLRGLMIAVMLAALMSSLTSIFNSSSTLFTMDIWRRLRPRS 420 Query: 391 SEARAIMLSRGLAFGYGLLCLGMAYI----SSQMGPVLQAAISIFGMVGGPLLGLFCLGM 446 E +++ R + L+ + +A+I S G + S+ + P+ +F LG+ Sbjct: 421 GERELLLVGRLVI--VALIGVSVAWIPVLQDSNSGQLFIYMQSVTSSLAPPVTAVFVLGV 478 Query: 447 FFPCANPPGAVVGLLAGLVM 466 F+ AN GA GL+AGLV+ Sbjct: 479 FWRRANEQGAFWGLIAGLVV 498 >gi|17941285 solute carrier family 5 (sodium/glucose cotransporter), member 11 [Homo sapiens] Length = 675 Score = 119 bits (299), Expect = 6e-27 Identities = 136/545 (24%), Positives = 235/545 (43%), Gaps = 49/545 (8%) Query: 28 DYVVFVLLLVLSLAIGLYHACRGWGRHTVGELLMADRKMGCLPVALSLLATFQSAVAILG 87 D V VL + LA+GL+ + R TV +A M PV SL A+ + +G Sbjct: 28 DIAVLVLYFLFVLAVGLWSTVKT-KRDTVKGYFLAGGDMVWWPVGASLFASNVGSGHFIG 86 Query: 88 VPSEIYRFGTQYWFLGCCYFLGLLIPAHIFIPVFYRLHLTSAYEYLELRFNKT-VRVCGT 146 + G +L+ A IF+P++ +T+ EYL RF + + Sbjct: 87 LAGSGAATGISVSAYELNGLFSVLMLAWIFLPIYIAGQVTTMPEYLRKRFGGIRIPIILA 146 Query: 147 VTFIFQMVIY-MGVVLYAPSLALNAVTGFDLWLSVLALGIVCTVYTALGGLKAVIWTDVF 205 V ++F + + V +YA ++ + DL+L+++ L + VYT GGL AVI+TD Sbjct: 147 VLYLFIYIFTKISVDMYAGAIFIQQSLHLDLYLAIVGLLAITAVYTVAGGLAAVIYTDAL 206 Query: 206 QTLVMFLGQLAVIIVGSAKVGGLGRV-----WAVASQHG--------RISGFELDPDPFV 252 QTL+M +G L ++ A VGG+ + A+AS R F + DP Sbjct: 207 QTLIMLIGALTLMGYSFAAVGGMEGLKEKYFLALASNRSENSSCGLPREDAFHIFRDPLT 266 Query: 253 RHTFWT-LAFGGVFMMLSLYGVNQAQVQRYLSSRTEKAAVLSCYAVFPFQQVSLCVGCLI 311 W + FG L + +Q VQR L+++ A + + L + Sbjct: 267 SDLPWPGVLFGMSIPSLWYWCTDQVIVQRTLAAKNLSHAKGGALMAAYLKVLPLFIMVFP 326 Query: 312 GLVMFAYYQEY-----PMSIQQAQAAP----DQFVLYFVMDLLKGLPGLPGLFIACLFSG 362 G+V + + P Q+ + P D V++LL GL GL +A + + Sbjct: 327 GMVSRILFPDQVACADPEICQKICSNPSGCSDIAYPKLVLELLP--TGLRGLMMAVMVAA 384 Query: 363 SLSTISSAFNSLATVTMEDLIRPWFPEFSEARAIMLSRGLAFGYGLLCLGMAYI----SS 418 +S+++S FNS +T+ DL P SE +++ R F L+ + + +I +S Sbjct: 385 LMSSLTSIFNSASTIFTMDLWNHLRPRASEKELMIVGR--VFVLLLVLVSILWIPVVQAS 442 Query: 419 QMGPVLQAAISIFGMVGGPLLGLFCLGMFFPCANPPGAVVGLLAGLVMAFWIGIGSIVTS 478 Q G + SI + P+ +F +G F+ N GA GL++GL+ +G+ +V Sbjct: 443 QGGQLFIYIQSISSYLQPPVAVVFIMGCFWKRTNEKGAFWGLISGLL----LGLVRLVLD 498 Query: 479 MGFSMPPSPSNGSSFSLPTN---------LTVATVTTLMPLTTFSKPTGLQRFYSLSYLW 529 + P L + L+ T+ T+ ++ F++P + L+ W Sbjct: 499 FIYVQPRCDQPDERPVLVKSIHYLYFSMILSTVTLITVSTVSWFTEPPSKEMVSHLT--W 556 Query: 530 YSAHN 534 ++ H+ Sbjct: 557 FTRHD 561 >gi|4507031 solute carrier family 5 (sodium/glucose cotransporter), member 1 [Homo sapiens] Length = 664 Score = 119 bits (297), Expect = 1e-26 Identities = 121/498 (24%), Positives = 217/498 (43%), Gaps = 63/498 (12%) Query: 28 DYVVFVLLLVLSLAIGLYHACRGWGRHTVGELLMADRKMGCLPVALSLLATFQSA----- 82 D + V+ V+ +A+GL+ A R TVG +A R M P+ SL A+ + Sbjct: 28 DISIIVIYFVVVMAVGLW-AMFSTNRGTVGGFFLAGRSMVWWPIGASLFASNIGSGHFVG 86 Query: 83 VAILGVPSEIYRFGTQYWFLGCCYFLGLLIPAHIFIPVFYRLHLTSAYEYLELRFN-KTV 141 +A G S I G ++ L LG L F+P++ + + + EYL RF + + Sbjct: 87 LAGTGAASGIAIGGFEWNALVLVVVLGWL-----FVPIYIKAGVVTMPEYLRKRFGGQRI 141 Query: 142 RV-CGTVTFIFQMVIYMGVVLYAPSLALNAVTGFDLWLSVLALGIVCTVYTALGGLKAVI 200 +V ++ + + + +++ ++ +N G +L+L++ L + +YT GGL AVI Sbjct: 142 QVYLSLLSLLLYIFTKISADIFSGAIFINLALGLNLYLAIFLLLAITALYTITGGLAAVI 201 Query: 201 WTDVFQTLVMFLGQLAVIIVGSAKVGG--------LGRVWAVASQHG----------RIS 242 +TD QT++M +G L + +VGG + + + S R Sbjct: 202 YTDTLQTVIMLVGSLILTGFAFHEVGGYDAFMEKYMKAIPTIVSDGNTTFQEKCYTPRAD 261 Query: 243 GFELDPDPFVRHTFWT-LAFGGVFMMLSLYGVNQAQVQRYLSSRTEKAAVLSCYAVFPFQ 301 F + DP W FG + L + +Q VQR LS++ C + Sbjct: 262 SFHIFRDPLTGDLPWPGFIFGMSILTLWYWCTDQVIVQRCLSAKNMSHVKGGCILCGYLK 321 Query: 302 QVSLCVGCLIGLVMFAYYQEYPMSIQQAQAAPDQFVLY--------------FVMDLLKG 347 + + + + G++ Y E + A P + Y V++L+ Sbjct: 322 LMPMFIMVMPGMISRILYTE-----KIACVVPSECEKYCGTKVGCTNIAYPTLVVELMPN 376 Query: 348 LPGLPGLFIACLFSGSLSTISSAFNSLATVTMEDLIRPWFPEFSEARAIMLSRGLAFGYG 407 GL GL ++ + + +S+++S FNS +T+ D+ SE ++ R F Sbjct: 377 --GLRGLMLSVMLASLMSSLTSIFNSASTLFTMDIYAKVRKRASEKELMIAGR--LFILV 432 Query: 408 LLCLGMAYI----SSQMGPVLQAAISIFGMVGGPLLGLFCLGMFFPCANPPGAVVGLLAG 463 L+ + +A++ S+Q G + SI +G P+ +F L +F+ N PGA GL+ G Sbjct: 433 LIGISIAWVPIVQSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFWKRVNEPGAFWGLILG 492 Query: 464 LVMAFWIGIGSIVTSMGF 481 L+ IGI ++T + Sbjct: 493 LL----IGISRMITEFAY 506 >gi|14140236 solute carrier family 5 (low affinity glucose cotransporter), member 4 [Homo sapiens] Length = 659 Score = 115 bits (288), Expect = 1e-25 Identities = 118/496 (23%), Positives = 209/496 (42%), Gaps = 45/496 (9%) Query: 28 DYVVFVLLLVLSLAIGLYHACRGWGRHTVGELLMADRKMGCLPVALSLLATFQSAVAILG 87 D V V+ ++ +A+GL+ A R T+G +A R M P+ SL A+ + +G Sbjct: 28 DISVIVIYFLVVMAVGLW-AMLKTNRGTIGGFFLAGRDMAWWPMGASLFASNIGSNHYVG 86 Query: 88 VPSEIYRFGTQYWFLGCCYFLGLLIPAHIFIPVFYRLHLTSAYEYLELRFN-KTVRVCGT 146 + G + LLI IF+P++ + + + EYL+ RF + ++V + Sbjct: 87 LAGTGAASGVATVTFEWTSSVMLLILGWIFVPIYIKSGVMTMPEYLKKRFGGERLQVYLS 146 Query: 147 VTFIFQMVIYM-GVVLYAPSLALNAVTGFDLWLSVLALGIVCTVYTALGGLKAVIWTDVF 205 + +F V+ + ++A ++ + G DL+L++ L + VYT GGL +VI+TD Sbjct: 147 ILSLFICVVLLISADIFAGAIFIKLALGLDLYLAIFILLAMTAVYTTTGGLASVIYTDTL 206 Query: 206 QTLVMFLGQLAVIIVGSAKVGGL------------------GRVWAVASQHGRISGFELD 247 QT++M +G ++ +VGG + + R F + Sbjct: 207 QTIIMLIGSFILMGFAFNEVGGYESFTEKYVNATPSVVEGDNLTISASCYTPRADSFHIF 266 Query: 248 PDPFVRHTFWT-LAFGGVFMMLSLYGVNQAQVQRYLSSRTEKAAVLSCYAVFPFQQVSLC 306 D W + FG L + NQ VQR L + +C + + + Sbjct: 267 RDAVTGDIPWPGIIFGMPITALWYWCTNQVIVQRCLCGKDMSHVKAACIMCAYLKLLPMF 326 Query: 307 VGCLIGLVMFAYYQEYPMSIQQAQAAPDQFVLYFVMDL-----------LKGLP-GLPGL 354 + + G++ Y + A P + V + +D+ L+ +P GL GL Sbjct: 327 LMVMPGMISRILYTD-----MVACVVPSECVKHCGVDVGCTNYAYPTMVLELMPQGLRGL 381 Query: 355 FIACLFSGSLSTISSAFNSLATVTMEDLIRPWFPEFSEARAIMLSRGLAFGYGLLCLGMA 414 ++ + + +S+++S FNS +T+ DL + SE +L G F L + + Sbjct: 382 MLSVMLASLMSSLTSIFNSASTLFTIDLYTKMRKQASEKE--LLIAGRIFVLLLTVVSIV 439 Query: 415 YIS----SQMGPVLQAAISIFGMVGGPLLGLFCLGMFFPCANPPGAVVGLLAGLVMAFWI 470 ++ SQ G ++ SI +G P+ +F L +F N GA GL+ GL M Sbjct: 440 WVPLVQVSQNGQLIHYTESISSYLGPPIAAVFVLAIFCKRVNEQGAFWGLMVGLAMGLIR 499 Query: 471 GIGSIVTSMGFSMPPS 486 I G + PS Sbjct: 500 MITEFAYGTGSCLAPS 515 >gi|206597483 solute carrier family 5 (sodium/glucose cotransporter), member 9 isoform 2 [Homo sapiens] Length = 681 Score = 107 bits (267), Expect = 3e-23 Identities = 144/588 (24%), Positives = 248/588 (42%), Gaps = 69/588 (11%) Query: 4 GVSTSAPLSPTSGTSVGMSTFSIMDYVVFVLLLVLSLAIGLYHACRGWGRHTVGELLMAD 63 GV T + VG+ + I V V+ V +A+G++ + R R T+G +A Sbjct: 16 GVRTETAPHIALDSRVGLHAYDIS---VVVIYFVFVIAVGIWSSIRA-SRGTIGGYFLAG 71 Query: 64 RKMGCLPVALSLLATFQSAVAILGVPSEIYRFGTQYWFLGCCYFLGLLIPAHIFIPVFYR 123 R M P+ SL+++ + +G+ G LL +F+PV+ Sbjct: 72 RSMSWWPIGASLMSSNVGSGLFIGLAGTGAAGGLAVGGFEWNATWLLLALGWVFVPVYIA 131 Query: 124 LHLTSAYEYLELRFN-KTVRVCGTV-TFIFQMVIYMGVVLYAPSLALNAVTGFDLWLSVL 181 + + +YL+ RF + ++V +V + I + + +++ +L + G++L+LS Sbjct: 132 AGVVTMPQYLKKRFGGQRIQVYMSVLSLILYIFTKISTDIFSGALFIQMALGWNLYLSTG 191 Query: 182 ALGIVCTVYTALGGLKAVIWTDVFQTLVMFLGQLAVIIVGSAKVG---GLGRVWAVASQH 238 L +V VYT GGL AVI+TD QT++M G L ++ +G VG GL + + A + Sbjct: 192 ILLVVTAVYTIAGGLMAVIYTDALQTVIMVGGALVLMFLGFQDVGWYPGLEQRYRQAIPN 251 Query: 239 ----------GRISGFELDPDPFVRHTFWT-LAFGGVFMMLSLYGVNQAQVQRYLS---- 283 R F + DP W L FG + + +Q VQR LS Sbjct: 252 VTVPNTTCHLPRPDAFHILRDPVSGDIPWPGLIFGLTVLATWCWCTDQVIVQRSLSAKSL 311 Query: 284 SRTEKAAVLSCYAVFPFQQVSLCVGCLIGLVMFAYYQEY-----PMSIQQAQAA--PDQF 336 S + +VL Y + + + + G++ A + + P Q+ A Sbjct: 312 SHAKGGSVLGGY----LKILPMFFIVMPGMISRALFPDEVGCVDPDVCQRICGARVGCSN 367 Query: 337 VLYFVMDLLKGLPGLPGLFIACLFSGSLSTISSAFNSLATVTMEDLIRPWFPEFSEARAI 396 + Y + + GL GL IA + + +S+++S FNS +T+ D+ + + + +E + Sbjct: 368 IAYPKLVMALMPVGLRGLMIAVIMAALMSSLTSIFNSSSTLFTIDVWQRFRRKSTEQELM 427 Query: 397 MLSRGLAFGYGLLCLGMAYI----SSQMGPVLQAAISIFGMVGGPLLGLFCLGMFFPCAN 452 ++ R F L+ + + +I SS G + ++ + P+ LF L +F Sbjct: 428 VVGR--VFVVFLVVISILWIPIIQSSNSGQLFDYIQAVTSYLAPPITALFLLAIFCKRVT 485 Query: 453 PPGAVVGLLAGLVMAFWIGIGSIVTSMGFSMPPSPSNGSSFSLPTNL------------- 499 PGA GL+ GL G+G + + FS P+P+ G P L Sbjct: 486 EPGAFWGLVFGL------GVGLLRMILEFSY-PAPACGEVDRRPAVLKDFHYLYFAILLC 538 Query: 500 --------TVATVTTLMPLTTFSKPTGLQRFYSLSYLWYSAHNSTTVI 539 V+ TT +P ++ T R LS L AH ST I Sbjct: 539 GLTAIVIVIVSLCTTPIPEEQLTRLTWWTRNCPLSELEKEAHESTPEI 586 >gi|4507033 solute carrier family 5 (sodium/glucose cotransporter), member 2 [Homo sapiens] Length = 672 Score = 99.4 bits (246), Expect = 9e-21 Identities = 124/503 (24%), Positives = 217/503 (43%), Gaps = 69/503 (13%) Query: 28 DYVVFVLLLVLSLAIGLYHACRGWGRHTVGELLMADRKMGCLPVALSLLATFQSA----- 82 D +V +L + +GL+ CR R TVG +A R M PV SL A+ + Sbjct: 25 DILVIAAYFLLVIGVGLWSMCRT-NRGTVGGYFLAGRSMVWWPVGASLFASNIGSGHFVG 83 Query: 83 VAILGVPSEIYRFGTQYWFLGCCYFLGLLIPAHIFIPVFYRLHLTSAYEYLELRFN-KTV 141 +A G S + G ++ L LG L F PV+ + + +YL RF + + Sbjct: 84 LAGTGAASGLAVAGFEWNALFVVLLLGWL-----FAPVYLTAGVITMPQYLRKRFGGRRI 138 Query: 142 RVCGTVTFIFQMVIY-MGVVLYAPSLALNAVTGFDLWLSVLALGIVCTVYTALGGLKAVI 200 R+ +V +F + + V +++ ++ + G++++ SV+AL + +YT GGL A++ Sbjct: 139 RLYLSVLSLFLYIFTKISVDMFSGAVFIQQALGWNIYASVIALLGITMIYTVTGGLAALM 198 Query: 201 WTDVFQTLVMFLGQLAVIIVGSA--KVGG--------LGRVWAVASQH----GRISGFEL 246 +TD QT V+ G A I++G A +VGG LG ++ G IS F Sbjct: 199 YTDTVQTFVILGG--ACILMGYAFHEVGGYSGLFDKYLGAATSLTVSEDPAVGNISSFCY 256 Query: 247 DPDP----FVRHTF-----WTLAFGGVFMMLSLYGV-NQAQVQRYLSSRTEKAAVLSCYA 296 P P +RH W G+ ++ Y +Q VQR L+ ++ C Sbjct: 257 RPRPDSYHLLRHPVTGDLPWPALLLGLTIVSGWYWCSDQVIVQRCLAGKSLTHIKAGCIL 316 Query: 297 VFPFQQVSLCVGCLIGLVMFAYYQEYPMSI------QQAQAAPDQFVLYFVMDLLKGLP- 349 + + + + G++ Y + + + + + ++K +P Sbjct: 317 CGYLKLTPMFLMVMPGMISRILYPDEVACVVPEVCRRVCGTEVGCSNIAYPRLVVKLMPN 376 Query: 350 GLPGLFIACLFSGSLSTISSAFNSLATVTMEDLIRPWFPEFSEARAIMLSRGLAFGYGLL 409 GL GL +A + + +S+++S FNS +T+ D+ P + +++ R L Sbjct: 377 GLRGLMLAVMLAALMSSLASIFNSSSTLFTMDIYTRLRPRAGDRELLLVGR-------LW 429 Query: 410 CLGMAYISSQMGPVLQAA---------ISIFGMVGGPLLGLFCLGMFFPCANPPGAVVGL 460 + + +S PV+QAA ++ + P+ +F L +F P N GA GL Sbjct: 430 VVFIVVVSVAWLPVVQAAQGGQLFDYIQAVSSYLAPPVSAVFVLALFVPRVNEQGAFWGL 489 Query: 461 LAGLVMA-------FWIGIGSIV 476 + GL+M F G GS V Sbjct: 490 IGGLLMGLARLIPEFSFGSGSCV 512 >gi|206597487 solute carrier family 5 (sodium/glucose cotransporter), member 9 isoform 1 [Homo sapiens] Length = 706 Score = 98.6 bits (244), Expect = 2e-20 Identities = 146/613 (23%), Positives = 251/613 (40%), Gaps = 94/613 (15%) Query: 4 GVSTSAPLSPTSGTSVGMSTFSIMDYVVFVLLLVLSLAIGLYHACRGWGRHTVGELLMAD 63 GV T + VG+ + I V V+ V +A+G++ + R R T+G +A Sbjct: 16 GVRTETAPHIALDSRVGLHAYDIS---VVVIYFVFVIAVGIWSSIRA-SRGTIGGYFLAG 71 Query: 64 RKMGCLPVALSLLATFQSAVAILGVPSEIYRFGTQY----WFLGCCYFLG---------- 109 R M P+ SL+++ + +G+ G W + G Sbjct: 72 RSMSWWPIGASLMSSNVGSGLFIGLAGTGAAGGLAVGGFEWNMRKSRSGGDRGIHPRSHG 131 Query: 110 -----------LLIPAHIFIPVFYRLHLTSAYEYLELRFN-KTVRVCGTV-TFIFQMVIY 156 LL +F+PV+ + + +YL+ RF + ++V +V + I + Sbjct: 132 RTGVRSQATWLLLALGWVFVPVYIAAGVVTMPQYLKKRFGGQRIQVYMSVLSLILYIFTK 191 Query: 157 MGVVLYAPSLALNAVTGFDLWLSVLALGIVCTVYTALGGLKAVIWTDVFQTLVMFLGQLA 216 + +++ +L + G++L+LS L +V VYT GGL AVI+TD QT++M G L Sbjct: 192 ISTDIFSGALFIQMALGWNLYLSTGILLVVTAVYTIAGGLMAVIYTDALQTVIMVGGALV 251 Query: 217 VIIVGSAKVG---GLGRVWAVASQH----------GRISGFELDPDPFVRHTFWT-LAFG 262 ++ +G VG GL + + A + R F + DP W L FG Sbjct: 252 LMFLGFQDVGWYPGLEQRYRQAIPNVTVPNTTCHLPRPDAFHILRDPVSGDIPWPGLIFG 311 Query: 263 GVFMMLSLYGVNQAQVQRYLS----SRTEKAAVLSCYAVFPFQQVSLCVGCLIGLVMFAY 318 + + +Q VQR LS S + +VL Y + + + + G++ A Sbjct: 312 LTVLATWCWCTDQVIVQRSLSAKSLSHAKGGSVLGGY----LKILPMFFIVMPGMISRAL 367 Query: 319 YQEY-----PMSIQQAQAA--PDQFVLYFVMDLLKGLPGLPGLFIACLFSGSLSTISSAF 371 + + P Q+ A + Y + + GL GL IA + + +S+++S F Sbjct: 368 FPDEVGCVDPDVCQRICGARVGCSNIAYPKLVMALMPVGLRGLMIAVIMAALMSSLTSIF 427 Query: 372 NSLATVTMEDLIRPWFPEFSEARAIMLSRGLAFGYGLLCLGMAYI----SSQMGPVLQAA 427 NS +T+ D+ + + + +E +++ R F L+ + + +I SS G + Sbjct: 428 NSSSTLFTIDVWQRFRRKSTEQELMVVGR--VFVVFLVVISILWIPIIQSSNSGQLFDYI 485 Query: 428 ISIFGMVGGPLLGLFCLGMFFPCANPPGAVVGLLAGLVMAFWIGIGSIVTSMGFSMPPSP 487 ++ + P+ LF L +F PGA GL+ GL G+G + + FS P+P Sbjct: 486 QAVTSYLAPPITALFLLAIFCKRVTEPGAFWGLVFGL------GVGLLRMILEFSY-PAP 538 Query: 488 SNGSSFSLPTNL---------------------TVATVTTLMPLTTFSKPTGLQRFYSLS 526 + G P L V+ TT +P ++ T R LS Sbjct: 539 ACGEVDRRPAVLKDFHYLYFAILLCGLTAIVIVIVSLCTTPIPEEQLTRLTWWTRNCPLS 598 Query: 527 YLWYSAHNSTTVI 539 L AH ST I Sbjct: 599 ELEKEAHESTPEI 611 >gi|110835708 solute carrier family 5 (inositol transporters), member 3 [Homo sapiens] Length = 718 Score = 89.4 bits (220), Expect = 9e-18 Identities = 113/508 (22%), Positives = 212/508 (41%), Gaps = 53/508 (10%) Query: 28 DYVVFVLLLVLSLAIGLYHACRGWGRHTVGELLMADRKMGCLPVALSLLATFQSAVAILG 87 D + L +L + IG + + R TV +A R M + + SL + + +G Sbjct: 9 DIAIVALYFILVMCIGFFAMWKS-NRSTVSGYFLAGRSMTWVTIGASLFVSNIGSEHFIG 67 Query: 88 VPSE--IYRFGTQYWFLGCCYFLGLLIPAHIFIPVFYRLHLTSAYEYLELRF--NKTVRV 143 + F W L LL +FIP++ R + + EYL RF ++ Sbjct: 68 LAGSGAASGFAVGAWEFNALLLLQLL--GWVFIPIYIRSGVYTMPEYLSKRFGGHRIQVY 125 Query: 144 CGTVTFIFQMVIYMGVVLYAPSLALNAVTGFDLWLSVLALGIVCTVYTALGGLKAVIWTD 203 ++ I + + V LY+ +L + G++L++SV+ L + + T GGL AVI+TD Sbjct: 126 FAALSLILYIFTKLSVDLYSGALFIQESLGWNLYVSVILLIGMTALLTVTGGLVAVIYTD 185 Query: 204 VFQTLVMFLGQLAVIIVGSAKVGGLGRV---WAVASQH----------GRISGFELDP-- 248 Q L+M +G L ++I+ ++GG V + +AS + + P Sbjct: 186 TLQALLMIIGALTLMIISIMEIGGFEEVKRRYMLASPDVTSILLTYNLSNTNSCNVSPKK 245 Query: 249 -------DPFVRHTFWT-LAFGGVFMMLSLYGVNQAQVQRYLSSRT---EKAAVLSCYAV 297 +P W G + + +Q VQR L+++ K + L + Sbjct: 246 EALKMLRNPTDEDVPWPGFILGQTPASVWYWCADQVIVQRVLAAKNIAHAKGSTLMAGFL 305 Query: 298 FPFQQVSLCVGCLIGLVMF-----AYYQEYPMSIQQAQAAPDQFVLYFVMDLLKGLP-GL 351 + V +I ++F E+ M + ++A + + ++K +P GL Sbjct: 306 KLLPMFIIVVPGMISRILFTDDIACINPEHCMLVCGSRAGCSN--IAYPRLVMKLVPVGL 363 Query: 352 PGLFIACLFSGSLSTISSAFNSLATVTMEDLIRPWFPEFSEARAIMLSRGLAFGYGLLCL 411 GL +A + + +S + S FNS +T+ D+ + + + +R +M+ G F ++ + Sbjct: 364 RGLMMAVMIAALMSDLDSIFNSASTIFTLDVYK-LIRKSASSRELMIV-GRIFVAFMVVI 421 Query: 412 GMAY----ISSQMGPVLQAAISIFGMVGGPLLGLFCLGMFFPCANPPGAVVGLLAGLVMA 467 +A+ + Q G + + + P+ LF L +F+ N GA G +AG V Sbjct: 422 SIAWVPIIVEMQGGQMYLYIQEVADYLTPPVAALFLLAIFWKRCNEQGAFYGGMAGFV-- 479 Query: 468 FWIGIGSIVTSMGFSMP--PSPSNGSSF 493 +G ++ + + P P N F Sbjct: 480 --LGAVRLILAFAYRAPECDQPDNRPGF 505 >gi|11141885 solute carrier family 5 (choline transporter), member 7 [Homo sapiens] Length = 580 Score = 58.2 bits (139), Expect = 2e-08 Identities = 111/477 (23%), Positives = 193/477 (40%), Gaps = 68/477 (14%) Query: 24 FSIMDYVVFVLLLVLSLAIGLYHACR----GWGRHTVGELLMADRKMGCLPVALSLLATF 79 F + + ++ +L L +G++ A R G +++ R +G L ++ AT+ Sbjct: 3 FHVEGLIAIIVFYLLILLVGIWAAWRTKNSGSAEERSEAIIVGGRDIGLLVGGFTMTATW 62 Query: 80 QSAVAILGVPSEIYRFGTQYWFLGCCYFLGLLIPAHIFIPVFYRLHLTSAYEYLELRFNK 139 I G +Y G GL A P+ Y L L L F K Sbjct: 63 VGGGYINGTAEAVYVPG-----------YGL---AWAQAPIGYSLSLILG----GLFFAK 104 Query: 140 TVRVCGTVTFI--FQMVI--YMGVVLYAPSL----------------ALNAVTGFDLWLS 179 +R G VT + FQ + MG +L+ P+L ++ + D+ +S Sbjct: 105 PMRSKGYVTMLDPFQQIYGKRMGGLLFIPALMGEMFWAAAIFSALGATISVIIDVDMHIS 164 Query: 180 VLALGIVCTVYTALGGLKAVIWTDVFQTLVMFLGQLAVI--IVGSAKVGGLGRVWAVASQ 237 V+ ++ T+YT +GGL +V +TDV Q +F+G + + V +G AV ++ Sbjct: 165 VIISALIATLYTLVGGLYSVAYTDVVQLFCIFVGLWISVPFALSHPAVADIG-FTAVHAK 223 Query: 238 HGRISGFELDPDPFVRHTFWTLAFGGVFMMLSLYGVN-QAQVQRYLSSRTEK-AAVLSCY 295 + + +D ++ F++L L G+ QA QR LSS + A VLS Sbjct: 224 YQKPWLGTVDSSE-------VYSWLDSFLLLMLGGIPWQAYFQRVLSSSSATYAQVLSFL 276 Query: 296 AVFPFQQVSL------CVGCLIGLVMFAYYQEYPMSIQQAQAAPDQFVLYFVMDLLKGLP 349 A F +++ +G AY P + ++A VL ++ + Sbjct: 277 AAFGCLVMAIPAILIGAIGASTDWNQTAYGLPDPKTTEEADMIL-PIVLQYLCPVYISFF 335 Query: 350 GLPGLFIACLFSGSLSTISSAFNSLATVTMEDLIRPWFPEFSEARAIMLSRGLAFGYGLL 409 GL G A + S + S+I SA + A + R S+ + + R F +G Sbjct: 336 GL-GAVSAAVMSSADSSILSASSMFARNIYQLSFR---QNASDKEIVWVMRITVFVFGAS 391 Query: 410 CLGMAYISSQMGPVLQAAISIFGMVGGPLLGLFCLGMFFPCANPPGAVVGLLAGLVM 466 MA ++ + + + + +V P L C+ +F N GAV G ++GL + Sbjct: 392 ATAMALLTKTVYGLWYLSSDLVYIVIFP--QLLCV-LFVKGTNTYGAVAGYVSGLFL 445 >gi|21361423 solute carrier family 39 (zinc transporter), member 1 [Homo sapiens] Length = 324 Score = 35.4 bits (80), Expect = 0.16 Identities = 55/215 (25%), Positives = 83/215 (38%), Gaps = 43/215 (20%) Query: 262 GGVFMMLSLYGVNQAQVQRYLSSRTEKAAVLSCYAVFPFQQVSLCVGCLIGLVM----FA 317 GGVF+ L + + YL++ E A L FP Q+ L +G + LVM A Sbjct: 77 GGVFLATCLLDL----LPDYLAAIDEALAALHVTLQFPLQEFILAMGFFLVLVMEQITLA 132 Query: 318 Y-YQEYPMSIQQAQA-------APDQFVLYFVMDLLKGLPGLPGLFIACLFSGSLSTISS 369 Y Q P +++ +A P + + G P P AC+ SL+ + S Sbjct: 133 YKEQSGPSPLEETRALLGTVNGGPQHWHDGPGVPQASGAPATPSALRACVLVFSLA-LHS 191 Query: 370 AFNSLATVTMEDLIRPWFPEFSEARAIMLSRGLAFGYGLLCLGMAYISSQMGPVLQAAIS 429 F LA D ARA+ L L G+L + ++ +LQ+ + Sbjct: 192 VFEGLAVGLQRD----------RARAMELCLALLLHKGILAVSLSL------RLLQSHLR 235 Query: 430 IFGMVGGPLLGLFCLGMFFPCANPPGAVVGLLAGL 464 + G G+ F C P G +GL A L Sbjct: 236 AQVVAG--------CGILFSCMTPLG--IGLGAAL 260 >gi|28872803 myeloid translocation gene on chromosome 16 isoform MTG16a [Homo sapiens] Length = 653 Score = 32.7 bits (73), Expect = 1.0 Identities = 36/115 (31%), Positives = 50/115 (43%), Gaps = 8/115 (6%) Query: 473 GSIVTSMGFSMPPSPSNGSSFSLPTNLTVATVTTLMPLTTFSKPTGLQRFYSLSYLWYSA 532 G+ T GFS P+ S+ +S S L L F T LQ+F S + Sbjct: 140 GAPCTPNGFSNGPATSSTASLSTQHLPPACGARQLSKLKRFL--TTLQQFGS--DISPEI 195 Query: 533 HNSTTVIVVGLIVSLLTGRMRGRSLNPATIYP----VLPKLLSLLPLSCQKRLHC 583 +V+GL+ S LT L AT +P V+P L + LPL ++ LHC Sbjct: 196 GERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHC 250 >gi|28872805 myeloid translocation gene on chromosome 16 isoform MTG16b [Homo sapiens] Length = 567 Score = 32.7 bits (73), Expect = 1.0 Identities = 36/115 (31%), Positives = 50/115 (43%), Gaps = 8/115 (6%) Query: 473 GSIVTSMGFSMPPSPSNGSSFSLPTNLTVATVTTLMPLTTFSKPTGLQRFYSLSYLWYSA 532 G+ T GFS P+ S+ +S S L L F T LQ+F S + Sbjct: 54 GAPCTPNGFSNGPATSSTASLSTQHLPPACGARQLSKLKRFL--TTLQQFGS--DISPEI 109 Query: 533 HNSTTVIVVGLIVSLLTGRMRGRSLNPATIYP----VLPKLLSLLPLSCQKRLHC 583 +V+GL+ S LT L AT +P V+P L + LPL ++ LHC Sbjct: 110 GERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHC 164 >gi|40354205 aldolase B, fructose-bisphosphate [Homo sapiens] Length = 364 Score = 32.0 bits (71), Expect = 1.8 Identities = 23/74 (31%), Positives = 36/74 (48%), Gaps = 5/74 (6%) Query: 333 PDQFVLYFVMDLLKGLPG-LPGLFIACLFSGSLSTISSAFNSLATVTMEDLIRPWFPEFS 391 P+Q + V L + +P +PG+ C SG +S + N L + + L +PW FS Sbjct: 246 PEQVAMATVTALHRTVPAAVPGI---CFLSGGMSEEDATLN-LNAINLCPLPKPWKLSFS 301 Query: 392 EARAIMLSRGLAFG 405 RA+ S A+G Sbjct: 302 YGRALQASALAAWG 315 >gi|45580709 unc-93 homolog B1 [Homo sapiens] Length = 597 Score = 32.0 bits (71), Expect = 1.8 Identities = 24/87 (27%), Positives = 39/87 (44%), Gaps = 6/87 (6%) Query: 390 FSEARAIMLSRGLAFGYGLLCLGMAYISSQMGPVLQAAISIFGMVGGPLLGLFCLGMFFP 449 +S + G+A GYG+ +G+ ++ L A S+ G LLGL L + P Sbjct: 349 YSGFEVLFACTGIALGYGVCSVGLERLA-----YLLVAYSL-GASAASLLGLLGLWLPRP 402 Query: 450 CANPPGAVVGLLAGLVMAFWIGIGSIV 476 GA V LL ++ FW + ++ Sbjct: 403 VPLVAGAGVHLLLTFILFFWAPVPRVL 429 >gi|28329422 acute myelogenous leukemia 1 translocation 1 protein isoform MTG8c [Homo sapiens] Length = 567 Score = 31.2 bits (69), Expect = 3.0 Identities = 34/108 (31%), Positives = 47/108 (43%), Gaps = 8/108 (7%) Query: 480 GFSMPPSPSNGSSFSLPTNLTVATVTTLMPLTTFSKPTGLQRFYSLSYLWYSAHNSTTVI 539 GFS PS S+ SS + L L F T LQ+F + + + Sbjct: 59 GFSNGPSSSSSSSLANQQLPPACGARQLSKLKRFL--TTLQQFGN--DISPEIGERVRTL 114 Query: 540 VVGLIVSLLTGRMRGRSLNPATIYP----VLPKLLSLLPLSCQKRLHC 583 V+GL+ S LT L AT +P V+P L + LPL ++ LHC Sbjct: 115 VLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHC 162 >gi|28329419 acute myelogenous leukemia 1 translocation 1 protein isoform MTG8c [Homo sapiens] Length = 567 Score = 31.2 bits (69), Expect = 3.0 Identities = 34/108 (31%), Positives = 47/108 (43%), Gaps = 8/108 (7%) Query: 480 GFSMPPSPSNGSSFSLPTNLTVATVTTLMPLTTFSKPTGLQRFYSLSYLWYSAHNSTTVI 539 GFS PS S+ SS + L L F T LQ+F + + + Sbjct: 59 GFSNGPSSSSSSSLANQQLPPACGARQLSKLKRFL--TTLQQFGN--DISPEIGERVRTL 114 Query: 540 VVGLIVSLLTGRMRGRSLNPATIYP----VLPKLLSLLPLSCQKRLHC 583 V+GL+ S LT L AT +P V+P L + LPL ++ LHC Sbjct: 115 VLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHC 162 >gi|28329416 acute myelogenous leukemia 1 translocation 1 protein isoform MTG8b [Homo sapiens] Length = 604 Score = 31.2 bits (69), Expect = 3.0 Identities = 34/108 (31%), Positives = 47/108 (43%), Gaps = 8/108 (7%) Query: 480 GFSMPPSPSNGSSFSLPTNLTVATVTTLMPLTTFSKPTGLQRFYSLSYLWYSAHNSTTVI 539 GFS PS S+ SS + L L F T LQ+F + + + Sbjct: 96 GFSNGPSSSSSSSLANQQLPPACGARQLSKLKRFL--TTLQQFGN--DISPEIGERVRTL 151 Query: 540 VVGLIVSLLTGRMRGRSLNPATIYP----VLPKLLSLLPLSCQKRLHC 583 V+GL+ S LT L AT +P V+P L + LPL ++ LHC Sbjct: 152 VLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHC 199 >gi|4757916 acute myelogenous leukemia 1 translocation 1 protein isoform MTG8a [Homo sapiens] Length = 577 Score = 31.2 bits (69), Expect = 3.0 Identities = 34/108 (31%), Positives = 47/108 (43%), Gaps = 8/108 (7%) Query: 480 GFSMPPSPSNGSSFSLPTNLTVATVTTLMPLTTFSKPTGLQRFYSLSYLWYSAHNSTTVI 539 GFS PS S+ SS + L L F T LQ+F + + + Sbjct: 69 GFSNGPSSSSSSSLANQQLPPACGARQLSKLKRFL--TTLQQFGN--DISPEIGERVRTL 124 Query: 540 VVGLIVSLLTGRMRGRSLNPATIYP----VLPKLLSLLPLSCQKRLHC 583 V+GL+ S LT L AT +P V+P L + LPL ++ LHC Sbjct: 125 VLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLLQRELLHC 172 >gi|31543630 solute carrier family 20 (phosphate transporter), member 1 [Homo sapiens] Length = 679 Score = 31.2 bits (69), Expect = 3.0 Identities = 21/83 (25%), Positives = 42/83 (50%), Gaps = 6/83 (7%) Query: 436 GPLLGLFCLGMFFPCANPPGAVVGLL----AGLVMAFWIGIGSIVTSMGFSMPP-SPSNG 490 GPL+ L+ + ++ + LL G+ + W+ ++ +MG + P +PS+G Sbjct: 540 GPLVALYLVYDTGDVSSKVATPIWLLLYGGVGICVGLWVWGRRVIQTMGKDLTPITPSSG 599 Query: 491 SSFSLPTNLTVATVTTL-MPLTT 512 S L + LTV + + +P++T Sbjct: 600 FSIELASALTVVIASNIGLPIST 622 >gi|225579067 solute carrier family 12, member 4 isoform e [Homo sapiens] Length = 1054 Score = 30.8 bits (68), Expect = 4.0 Identities = 27/96 (28%), Positives = 42/96 (43%), Gaps = 3/96 (3%) Query: 454 PGAVVGLLAGLVMAFWIGIGSIVTSMGFSMPPSPSNGSSFSLPTNLTVATVTTLMPLTTF 513 PGA G+L + + ++ G IV G +PS S L +AT T++ F Sbjct: 338 PGAAAGVLQENLWSAYLEKGDIVEKHGLPSADAPSLKESLPLYVVADIATSFTVLVGIFF 397 Query: 514 SKPTGLQRFYSLSYLWYSAHNSTTVIVVGLIVSLLT 549 TG+ + S A S I VG I++++T Sbjct: 398 PSVTGIMAGSNRSGDLRDAQKS---IPVGTILAIIT 430 >gi|225579065 solute carrier family 12, member 4 isoform d [Homo sapiens] Length = 1079 Score = 30.8 bits (68), Expect = 4.0 Identities = 27/96 (28%), Positives = 42/96 (43%), Gaps = 3/96 (3%) Query: 454 PGAVVGLLAGLVMAFWIGIGSIVTSMGFSMPPSPSNGSSFSLPTNLTVATVTTLMPLTTF 513 PGA G+L + + ++ G IV G +PS S L +AT T++ F Sbjct: 363 PGAAAGVLQENLWSAYLEKGDIVEKHGLPSADAPSLKESLPLYVVADIATSFTVLVGIFF 422 Query: 514 SKPTGLQRFYSLSYLWYSAHNSTTVIVVGLIVSLLT 549 TG+ + S A S I VG I++++T Sbjct: 423 PSVTGIMAGSNRSGDLRDAQKS---IPVGTILAIIT 455 >gi|225579063 solute carrier family 12, member 4 isoform c [Homo sapiens] Length = 1087 Score = 30.8 bits (68), Expect = 4.0 Identities = 27/96 (28%), Positives = 42/96 (43%), Gaps = 3/96 (3%) Query: 454 PGAVVGLLAGLVMAFWIGIGSIVTSMGFSMPPSPSNGSSFSLPTNLTVATVTTLMPLTTF 513 PGA G+L + + ++ G IV G +PS S L +AT T++ F Sbjct: 371 PGAAAGVLQENLWSAYLEKGDIVEKHGLPSADAPSLKESLPLYVVADIATSFTVLVGIFF 430 Query: 514 SKPTGLQRFYSLSYLWYSAHNSTTVIVVGLIVSLLT 549 TG+ + S A S I VG I++++T Sbjct: 431 PSVTGIMAGSNRSGDLRDAQKS---IPVGTILAIIT 463 >gi|225579061 solute carrier family 12, member 4 isoform b [Homo sapiens] Length = 1079 Score = 30.8 bits (68), Expect = 4.0 Identities = 27/96 (28%), Positives = 42/96 (43%), Gaps = 3/96 (3%) Query: 454 PGAVVGLLAGLVMAFWIGIGSIVTSMGFSMPPSPSNGSSFSLPTNLTVATVTTLMPLTTF 513 PGA G+L + + ++ G IV G +PS S L +AT T++ F Sbjct: 369 PGAAAGVLQENLWSAYLEKGDIVEKHGLPSADAPSLKESLPLYVVADIATSFTVLVGIFF 428 Query: 514 SKPTGLQRFYSLSYLWYSAHNSTTVIVVGLIVSLLT 549 TG+ + S A S I VG I++++T Sbjct: 429 PSVTGIMAGSNRSGDLRDAQKS---IPVGTILAIIT 461 >gi|4827006 solute carrier family 12, member 4 isoform a [Homo sapiens] Length = 1085 Score = 30.8 bits (68), Expect = 4.0 Identities = 27/96 (28%), Positives = 42/96 (43%), Gaps = 3/96 (3%) Query: 454 PGAVVGLLAGLVMAFWIGIGSIVTSMGFSMPPSPSNGSSFSLPTNLTVATVTTLMPLTTF 513 PGA G+L + + ++ G IV G +PS S L +AT T++ F Sbjct: 369 PGAAAGVLQENLWSAYLEKGDIVEKHGLPSADAPSLKESLPLYVVADIATSFTVLVGIFF 428 Query: 514 SKPTGLQRFYSLSYLWYSAHNSTTVIVVGLIVSLLT 549 TG+ + S A S I VG I++++T Sbjct: 429 PSVTGIMAGSNRSGDLRDAQKS---IPVGTILAIIT 461 >gi|62912479 major histocompatibility complex, class I, E precursor [Homo sapiens] Length = 358 Score = 29.6 bits (65), Expect = 8.8 Identities = 14/46 (30%), Positives = 26/46 (56%) Query: 449 PCANPPGAVVGLLAGLVMAFWIGIGSIVTSMGFSMPPSPSNGSSFS 494 P + P +VG++AGLV+ + G++V ++ + S G S+S Sbjct: 297 PASQPTIPIVGIIAGLVLLGSVVSGAVVAAVIWRKKSSGGKGGSYS 342 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.327 0.141 0.436 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 22,711,629 Number of Sequences: 37866 Number of extensions: 985426 Number of successful extensions: 3296 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 16 Number of HSP's successfully gapped in prelim test: 16 Number of HSP's that attempted gapping in prelim test: 3214 Number of HSP's gapped (non-prelim): 69 length of query: 635 length of database: 18,247,518 effective HSP length: 109 effective length of query: 526 effective length of database: 14,120,124 effective search space: 7427185224 effective search space used: 7427185224 T: 11 A: 40 X1: 15 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.7 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.