Guide to the Human Genome
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Search of human proteins with 10835079

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|10835079 gap junction protein, beta 5, 31.1kDa [Homo
sapiens]
         (273 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|10835079 gap junction protein, beta 5, 31.1kDa [Homo sapiens]      577   e-165
gi|23397464 gap junction protein, beta 4 [Homo sapiens]               334   4e-92
gi|54607056 connexin 31 [Homo sapiens]                                310   9e-85
gi|13128960 connexin 31 [Homo sapiens]                                310   9e-85
gi|38348412 gap junction protein, beta 7, 25kDa [Homo sapiens]        271   6e-73
gi|148233402 gap junction protein, beta 1, 32kDa [Homo sapiens]       254   4e-68
gi|4504005 gap junction protein, beta 1, 32kDa [Homo sapiens]         254   4e-68
gi|159032020 gap junction protein, beta 6 [Homo sapiens]              253   2e-67
gi|158966714 gap junction protein, beta 6 [Homo sapiens]              253   2e-67
gi|158966717 gap junction protein, beta 6 [Homo sapiens]              253   2e-67
gi|40254837 gap junction protein, beta 6 [Homo sapiens]               253   2e-67
gi|42558283 gap junction protein beta 2 [Homo sapiens]                244   8e-65
gi|55953076 connexin 50 [Homo sapiens]                                198   4e-51
gi|62865885 connexin 37 [Homo sapiens]                                189   2e-48
gi|22779877 connexin 46 [Homo sapiens]                                184   9e-47
gi|4504001 connexin 43 [Homo sapiens]                                 181   8e-46
gi|14211941 gap junction protein, alpha 10 [Homo sapiens]             177   9e-45
gi|31542845 gap junction protein, alpha 9, 59kDa [Homo sapiens]       176   1e-44
gi|32483412 connexin 40 [Homo sapiens]                                174   7e-44
gi|6631083 connexin 40 [Homo sapiens]                                 174   7e-44
gi|122939172 connexin 45 [Homo sapiens]                               144   1e-34
gi|69122473 connexin 45 [Homo sapiens]                                144   1e-34
gi|148839378 gap junction protein, delta 3, 31.9kDa [Homo sapiens]    129   2e-30
gi|145699105 connexin40.1 [Homo sapiens]                              126   2e-29
gi|31559821 gap junction protein, gamma 3, 30.2kDa [Homo sapiens]     111   8e-25
gi|45439367 gap junction protein, gamma 2, 47kDa [Homo sapiens]       107   1e-23
gi|10190698 gap junction protein, delta 2, 36kDa [Homo sapiens]       100   2e-21
gi|169171704 PREDICTED: similar to hCG1770601 [Homo sapiens]           72   5e-13
gi|169171845 PREDICTED: similar to hCG1770601 [Homo sapiens]           72   5e-13
gi|169171183 PREDICTED: similar to hCG1770601 [Homo sapiens]           72   5e-13

>gi|10835079 gap junction protein, beta 5, 31.1kDa [Homo sapiens]
          Length = 273

 Score =  577 bits (1486), Expect = e-165
 Identities = 273/273 (100%), Positives = 273/273 (100%)

Query: 1   MNWSIFEGLLSGVNKYSTAFGRIWLSLVFIFRVLVYLVTAERVWSDDHKDFDCNTRQPGC 60
           MNWSIFEGLLSGVNKYSTAFGRIWLSLVFIFRVLVYLVTAERVWSDDHKDFDCNTRQPGC
Sbjct: 1   MNWSIFEGLLSGVNKYSTAFGRIWLSLVFIFRVLVYLVTAERVWSDDHKDFDCNTRQPGC 60

Query: 61  SNVCFDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYREVQEKRHREAHGENSGRLYLNP 120
           SNVCFDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYREVQEKRHREAHGENSGRLYLNP
Sbjct: 61  SNVCFDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYREVQEKRHREAHGENSGRLYLNP 120

Query: 121 GKKRGGLWWTYVCSLVFKASVDIAFLYVFHSFYPKYILPPVVKCHADPCPNIVDCFISKP 180
           GKKRGGLWWTYVCSLVFKASVDIAFLYVFHSFYPKYILPPVVKCHADPCPNIVDCFISKP
Sbjct: 121 GKKRGGLWWTYVCSLVFKASVDIAFLYVFHSFYPKYILPPVVKCHADPCPNIVDCFISKP 180

Query: 181 SEKNIFTLFMVATAAICILLNLVELIYLVSKRCHECLAARKAQAMCTGHHPHGTTSSCKQ 240
           SEKNIFTLFMVATAAICILLNLVELIYLVSKRCHECLAARKAQAMCTGHHPHGTTSSCKQ
Sbjct: 181 SEKNIFTLFMVATAAICILLNLVELIYLVSKRCHECLAARKAQAMCTGHHPHGTTSSCKQ 240

Query: 241 DDLLSGDLIFLGSDSHPPLLPDRPRDHVKKTIL 273
           DDLLSGDLIFLGSDSHPPLLPDRPRDHVKKTIL
Sbjct: 241 DDLLSGDLIFLGSDSHPPLLPDRPRDHVKKTIL 273


>gi|23397464 gap junction protein, beta 4 [Homo sapiens]
          Length = 266

 Score =  334 bits (857), Expect = 4e-92
 Identities = 153/226 (67%), Positives = 177/226 (78%)

Query: 1   MNWSIFEGLLSGVNKYSTAFGRIWLSLVFIFRVLVYLVTAERVWSDDHKDFDCNTRQPGC 60
           MNW+  +GLLSGVNKYST   RIWLS+VFIFRVLVY+V AE VW D+ KDF CNT+QPGC
Sbjct: 1   MNWAFLQGLLSGVNKYSTVLSRIWLSVVFIFRVLVYVVAAEEVWDDEQKDFVCNTKQPGC 60

Query: 61  SNVCFDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYREVQEKRHREAHGENSGRLYLNP 120
            NVC+DEFFPVSHVRLWALQLILVTCPSLLVVMHVAYRE +E++H   HG N+  LY N 
Sbjct: 61  PNVCYDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYREERERKHHLKHGPNAPSLYDNL 120

Query: 121 GKKRGGLWWTYVCSLVFKASVDIAFLYVFHSFYPKYILPPVVKCHADPCPNIVDCFISKP 180
            KKRGGLWWTY+ SL+FKA+VD  FLY+FH  Y  Y +P VV C  +PCP+ VDC+IS+P
Sbjct: 121 SKKRGGLWWTYLLSLIFKAAVDAGFLYIFHRLYKDYDMPRVVACSVEPCPHTVDCYISRP 180

Query: 181 SEKNIFTLFMVATAAICILLNLVELIYLVSKRCHECLAARKAQAMC 226
           +EK +FT FMV TAAICILLNL E+ YLV KRC E    R  +  C
Sbjct: 181 TEKKVFTYFMVTTAAICILLNLSEVFYLVGKRCMEIFGPRHRRPRC 226


>gi|54607056 connexin 31 [Homo sapiens]
          Length = 270

 Score =  310 bits (794), Expect = 9e-85
 Identities = 137/240 (57%), Positives = 182/240 (75%), Gaps = 1/240 (0%)

Query: 1   MNWSIFEGLLSGVNKYSTAFGRIWLSLVFIFRVLVYLVTAERVWSDDHKDFDCNTRQPGC 60
           M+W   + LLSGVNKYSTAFGRIWLS+VF+FRVLVY+V AERVW D+ KDFDCNT+QPGC
Sbjct: 1   MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGC 60

Query: 61  SNVCFDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYREVQEKRHREAHGENSGRLYLNP 120
           +NVC+D +FP+S++RLWALQLI VTCPSLLV++HVAYRE +E+RHR+ HG+   +LY N 
Sbjct: 61  TNVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERRHRQKHGDQCAKLYDNA 120

Query: 121 GKKRGGLWWTYVCSLVFKASVDIAFLYVFHSFYPKYILPPVVKC-HADPCPNIVDCFISK 179
           GKK GGLWWTY+ SL+FK  ++  FLY+ H+ +  + +P +V+C +  PCPNIVDC+I++
Sbjct: 121 GKKHGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIVDCYIAR 180

Query: 180 PSEKNIFTLFMVATAAICILLNLVELIYLVSKRCHECLAARKAQAMCTGHHPHGTTSSCK 239
           P+EK IFT FMV  +A+CI+L + EL YL+  R    L   K +  C+        S+C+
Sbjct: 181 PTEKKIFTYFMVGASAVCIVLTICELCYLICHRVLRGLHKDKPRGGCSPSSSASRASTCR 240


>gi|13128960 connexin 31 [Homo sapiens]
          Length = 270

 Score =  310 bits (794), Expect = 9e-85
 Identities = 137/240 (57%), Positives = 182/240 (75%), Gaps = 1/240 (0%)

Query: 1   MNWSIFEGLLSGVNKYSTAFGRIWLSLVFIFRVLVYLVTAERVWSDDHKDFDCNTRQPGC 60
           M+W   + LLSGVNKYSTAFGRIWLS+VF+FRVLVY+V AERVW D+ KDFDCNT+QPGC
Sbjct: 1   MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGC 60

Query: 61  SNVCFDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYREVQEKRHREAHGENSGRLYLNP 120
           +NVC+D +FP+S++RLWALQLI VTCPSLLV++HVAYRE +E+RHR+ HG+   +LY N 
Sbjct: 61  TNVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERRHRQKHGDQCAKLYDNA 120

Query: 121 GKKRGGLWWTYVCSLVFKASVDIAFLYVFHSFYPKYILPPVVKC-HADPCPNIVDCFISK 179
           GKK GGLWWTY+ SL+FK  ++  FLY+ H+ +  + +P +V+C +  PCPNIVDC+I++
Sbjct: 121 GKKHGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIVDCYIAR 180

Query: 180 PSEKNIFTLFMVATAAICILLNLVELIYLVSKRCHECLAARKAQAMCTGHHPHGTTSSCK 239
           P+EK IFT FMV  +A+CI+L + EL YL+  R    L   K +  C+        S+C+
Sbjct: 181 PTEKKIFTYFMVGASAVCIVLTICELCYLICHRVLRGLHKDKPRGGCSPSSSASRASTCR 240


>gi|38348412 gap junction protein, beta 7, 25kDa [Homo sapiens]
          Length = 223

 Score =  271 bits (692), Expect = 6e-73
 Identities = 123/216 (56%), Positives = 161/216 (74%), Gaps = 7/216 (3%)

Query: 1   MNWSIFEGLLSGVNKYSTAFGRIWLSLVFIFRVLVYLVTAERVWSDDHKDFDCNTRQPGC 60
           M+W     LLSGVNKYST  G IWL++VF+FR+LVY+V AE VW D+ K+F+CN+RQPGC
Sbjct: 1   MSWMFLRDLLSGVNKYSTGTGWIWLAVVFVFRLLVYMVAAEHVWKDEQKEFECNSRQPGC 60

Query: 61  SNVCFDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYREVQEKRHREAHGENSGRLYLNP 120
            NVCFD+FFP+S VRLWALQLI+V+ PSLLVV+HVAY E +EKRHR+       +LY++P
Sbjct: 61  KNVCFDDFFPISQVRLWALQLIMVSTPSLLVVLHVAYHEGREKRHRK-------KLYVSP 113

Query: 121 GKKRGGLWWTYVCSLVFKASVDIAFLYVFHSFYPKYILPPVVKCHADPCPNIVDCFISKP 180
           G   GGLW+ Y+ SL+ K   +I FL +F+  Y  + +P ++KC   PCPN VDCFISKP
Sbjct: 114 GTMDGGLWYAYLISLIVKTGFEIGFLVLFYKLYDGFSVPYLIKCDLKPCPNTVDCFISKP 173

Query: 181 SEKNIFTLFMVATAAICILLNLVELIYLVSKRCHEC 216
           +EK IF LF+V T+ +CI+LN +EL +LV K   +C
Sbjct: 174 TEKTIFILFLVITSCLCIVLNFIELSFLVLKCFIKC 209


>gi|148233402 gap junction protein, beta 1, 32kDa [Homo sapiens]
          Length = 283

 Score =  254 bits (650), Expect = 4e-68
 Identities = 120/230 (52%), Positives = 166/230 (72%), Gaps = 15/230 (6%)

Query: 1   MNWSIFEGLLSGVNKYSTAFGRIWLSLVFIFRVLVYLVTAERVWSDDHKDFDCNTRQPGC 60
           MNW+    LLSGVN++STA GR+WLS++FIFR++V +V AE VW D+   F CNT QPGC
Sbjct: 1   MNWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGC 60

Query: 61  SNVCFDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYREVQEKR--HREAHGENSGRLYL 118
           ++VC+D+FFP+SHVRLW+LQLILV+ P+LLV MHVA+++  EK+    E HG+    L+L
Sbjct: 61  NSVCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQQHIEKKMLRLEGHGD---PLHL 117

Query: 119 NPGKKR-----GGLWWTYVCSLVFKASVDIAFLYVFHSFYPKYILPPVVKCHADPCPNIV 173
              K+      G LWWTYV S+VF+   +  F+YVF+  YP Y +  +VKC   PCPN V
Sbjct: 118 EEVKRHKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVRLVKCDVYPCPNTV 177

Query: 174 DCFISKPSEKNIFTLFMVATAAICILLNLVELIYLVSKRCHECLAARKAQ 223
           DCF+S+P+EK +FT+FM+A + ICI+LN+ E++YL+ + C     AR+AQ
Sbjct: 178 DCFVSRPTEKTVFTVFMLAASGICIILNVAEVVYLIIRAC-----ARRAQ 222


>gi|4504005 gap junction protein, beta 1, 32kDa [Homo sapiens]
          Length = 283

 Score =  254 bits (650), Expect = 4e-68
 Identities = 120/230 (52%), Positives = 166/230 (72%), Gaps = 15/230 (6%)

Query: 1   MNWSIFEGLLSGVNKYSTAFGRIWLSLVFIFRVLVYLVTAERVWSDDHKDFDCNTRQPGC 60
           MNW+    LLSGVN++STA GR+WLS++FIFR++V +V AE VW D+   F CNT QPGC
Sbjct: 1   MNWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGC 60

Query: 61  SNVCFDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYREVQEKR--HREAHGENSGRLYL 118
           ++VC+D+FFP+SHVRLW+LQLILV+ P+LLV MHVA+++  EK+    E HG+    L+L
Sbjct: 61  NSVCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQQHIEKKMLRLEGHGD---PLHL 117

Query: 119 NPGKKR-----GGLWWTYVCSLVFKASVDIAFLYVFHSFYPKYILPPVVKCHADPCPNIV 173
              K+      G LWWTYV S+VF+   +  F+YVF+  YP Y +  +VKC   PCPN V
Sbjct: 118 EEVKRHKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVRLVKCDVYPCPNTV 177

Query: 174 DCFISKPSEKNIFTLFMVATAAICILLNLVELIYLVSKRCHECLAARKAQ 223
           DCF+S+P+EK +FT+FM+A + ICI+LN+ E++YL+ + C     AR+AQ
Sbjct: 178 DCFVSRPTEKTVFTVFMLAASGICIILNVAEVVYLIIRAC-----ARRAQ 222


>gi|159032020 gap junction protein, beta 6 [Homo sapiens]
          Length = 261

 Score =  253 bits (645), Expect = 2e-67
 Identities = 116/248 (46%), Positives = 165/248 (66%), Gaps = 9/248 (3%)

Query: 1   MNWSIFEGLLSGVNKYSTAFGRIWLSLVFIFRVLVYLVTAERVWSDDHKDFDCNTRQPGC 60
           M+W      + GVNK+ST+ G++W++++FIFRV++ +V A+ VW D+ +DF CNT QPGC
Sbjct: 1   MDWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGC 60

Query: 61  SNVCFDEFFPVSHVRLWALQLILVTCPSLLVVMHVA-YREVQEKRHREAHGENSGRLYLN 119
            NVC+D FFPVSH+RLWALQLI V+ P+LLV MHVA YR    ++ R     N  +   +
Sbjct: 61  KNVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRNDFKDIED 120

Query: 120 PGKKR----GGLWWTYVCSLVFKASVDIAFLYVFHSFYPKYILPPVVKCHADPCPNIVDC 175
             K++    G LWWTY  S+ F+   + AF+YVF+  Y  Y LP V+KC  DPCPN+VDC
Sbjct: 121 IKKQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPNLVDC 180

Query: 176 FISKPSEKNIFTLFMVATAAICILLNLVELIYLVSKRCHECLAARKAQAMCTGHHPHGTT 235
           FIS+P+EK +FT+FM++ + IC+LLN+ EL YL+ K C      R  +A    +HP+   
Sbjct: 181 FISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFR----RSKRAQTQKNHPNHAL 236

Query: 236 SSCKQDDL 243
              KQ+++
Sbjct: 237 KESKQNEM 244


>gi|158966714 gap junction protein, beta 6 [Homo sapiens]
          Length = 261

 Score =  253 bits (645), Expect = 2e-67
 Identities = 116/248 (46%), Positives = 165/248 (66%), Gaps = 9/248 (3%)

Query: 1   MNWSIFEGLLSGVNKYSTAFGRIWLSLVFIFRVLVYLVTAERVWSDDHKDFDCNTRQPGC 60
           M+W      + GVNK+ST+ G++W++++FIFRV++ +V A+ VW D+ +DF CNT QPGC
Sbjct: 1   MDWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGC 60

Query: 61  SNVCFDEFFPVSHVRLWALQLILVTCPSLLVVMHVA-YREVQEKRHREAHGENSGRLYLN 119
            NVC+D FFPVSH+RLWALQLI V+ P+LLV MHVA YR    ++ R     N  +   +
Sbjct: 61  KNVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRNDFKDIED 120

Query: 120 PGKKR----GGLWWTYVCSLVFKASVDIAFLYVFHSFYPKYILPPVVKCHADPCPNIVDC 175
             K++    G LWWTY  S+ F+   + AF+YVF+  Y  Y LP V+KC  DPCPN+VDC
Sbjct: 121 IKKQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPNLVDC 180

Query: 176 FISKPSEKNIFTLFMVATAAICILLNLVELIYLVSKRCHECLAARKAQAMCTGHHPHGTT 235
           FIS+P+EK +FT+FM++ + IC+LLN+ EL YL+ K C      R  +A    +HP+   
Sbjct: 181 FISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFR----RSKRAQTQKNHPNHAL 236

Query: 236 SSCKQDDL 243
              KQ+++
Sbjct: 237 KESKQNEM 244


>gi|158966717 gap junction protein, beta 6 [Homo sapiens]
          Length = 261

 Score =  253 bits (645), Expect = 2e-67
 Identities = 116/248 (46%), Positives = 165/248 (66%), Gaps = 9/248 (3%)

Query: 1   MNWSIFEGLLSGVNKYSTAFGRIWLSLVFIFRVLVYLVTAERVWSDDHKDFDCNTRQPGC 60
           M+W      + GVNK+ST+ G++W++++FIFRV++ +V A+ VW D+ +DF CNT QPGC
Sbjct: 1   MDWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGC 60

Query: 61  SNVCFDEFFPVSHVRLWALQLILVTCPSLLVVMHVA-YREVQEKRHREAHGENSGRLYLN 119
            NVC+D FFPVSH+RLWALQLI V+ P+LLV MHVA YR    ++ R     N  +   +
Sbjct: 61  KNVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRNDFKDIED 120

Query: 120 PGKKR----GGLWWTYVCSLVFKASVDIAFLYVFHSFYPKYILPPVVKCHADPCPNIVDC 175
             K++    G LWWTY  S+ F+   + AF+YVF+  Y  Y LP V+KC  DPCPN+VDC
Sbjct: 121 IKKQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPNLVDC 180

Query: 176 FISKPSEKNIFTLFMVATAAICILLNLVELIYLVSKRCHECLAARKAQAMCTGHHPHGTT 235
           FIS+P+EK +FT+FM++ + IC+LLN+ EL YL+ K C      R  +A    +HP+   
Sbjct: 181 FISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFR----RSKRAQTQKNHPNHAL 236

Query: 236 SSCKQDDL 243
              KQ+++
Sbjct: 237 KESKQNEM 244


>gi|40254837 gap junction protein, beta 6 [Homo sapiens]
          Length = 261

 Score =  253 bits (645), Expect = 2e-67
 Identities = 116/248 (46%), Positives = 165/248 (66%), Gaps = 9/248 (3%)

Query: 1   MNWSIFEGLLSGVNKYSTAFGRIWLSLVFIFRVLVYLVTAERVWSDDHKDFDCNTRQPGC 60
           M+W      + GVNK+ST+ G++W++++FIFRV++ +V A+ VW D+ +DF CNT QPGC
Sbjct: 1   MDWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGC 60

Query: 61  SNVCFDEFFPVSHVRLWALQLILVTCPSLLVVMHVA-YREVQEKRHREAHGENSGRLYLN 119
            NVC+D FFPVSH+RLWALQLI V+ P+LLV MHVA YR    ++ R     N  +   +
Sbjct: 61  KNVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRNDFKDIED 120

Query: 120 PGKKR----GGLWWTYVCSLVFKASVDIAFLYVFHSFYPKYILPPVVKCHADPCPNIVDC 175
             K++    G LWWTY  S+ F+   + AF+YVF+  Y  Y LP V+KC  DPCPN+VDC
Sbjct: 121 IKKQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPNLVDC 180

Query: 176 FISKPSEKNIFTLFMVATAAICILLNLVELIYLVSKRCHECLAARKAQAMCTGHHPHGTT 235
           FIS+P+EK +FT+FM++ + IC+LLN+ EL YL+ K C      R  +A    +HP+   
Sbjct: 181 FISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFR----RSKRAQTQKNHPNHAL 236

Query: 236 SSCKQDDL 243
              KQ+++
Sbjct: 237 KESKQNEM 244


>gi|42558283 gap junction protein beta 2 [Homo sapiens]
          Length = 226

 Score =  244 bits (622), Expect = 8e-65
 Identities = 110/218 (50%), Positives = 153/218 (70%), Gaps = 5/218 (2%)

Query: 1   MNWSIFEGLLSGVNKYSTAFGRIWLSLVFIFRVLVYLVTAERVWSDDHKDFDCNTRQPGC 60
           M+W   + +L GVNK+ST+ G+IWL+++FIFR+++ +V A+ VW D+  DF CNT QPGC
Sbjct: 1   MDWGTLQTILGGVNKHSTSIGKIWLTVLFIFRIMILVVAAKEVWGDEQADFVCNTLQPGC 60

Query: 61  SNVCFDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYREVQEKR---HREAHGENSGRLY 117
            NVC+D +FP+SH+RLWALQLI V+ P+LLV MHVAYR  ++KR     E   E      
Sbjct: 61  KNVCYDHYFPISHIRLWALQLIFVSTPALLVAMHVAYRRHEKKRKFIKGEIKSEFKDIEE 120

Query: 118 LNPGKKR--GGLWWTYVCSLVFKASVDIAFLYVFHSFYPKYILPPVVKCHADPCPNIVDC 175
           +   K R  G LWWTY  S+ F+   + AF+YVF+  Y  + +  +VKC+A PCPN VDC
Sbjct: 121 IKTQKVRIEGSLWWTYTSSIFFRVIFEAAFMYVFYVMYDGFSMQRLVKCNAWPCPNTVDC 180

Query: 176 FISKPSEKNIFTLFMVATAAICILLNLVELIYLVSKRC 213
           F+S+P+EK +FT+FM+A + ICILLN+ EL YL+ + C
Sbjct: 181 FVSRPTEKTVFTVFMIAVSGICILLNVTELCYLLIRYC 218


>gi|55953076 connexin 50 [Homo sapiens]
          Length = 433

 Score =  198 bits (504), Expect = 4e-51
 Identities = 101/235 (42%), Positives = 146/235 (62%), Gaps = 20/235 (8%)

Query: 2   NWSIFEGLLSGVNKYSTAFGRIWLSLVFIFRVLVYLVTAERVWSDDHKDFDCNTRQPGCS 61
           +WS    +L  VN++ST  GR+WL+++FIFR+L+    AE VW D+  DF CNT+QPGC 
Sbjct: 3   DWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPGCE 62

Query: 62  NVCFDEFFPVSHVRLWALQLILVTCPSLLVVMH-VAYREVQEKR-HREAH---------- 109
           NVC+DE FP+SH+RLW LQ+I V+ PSL+ V H V Y  ++EKR  REA           
Sbjct: 63  NVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGTNG 122

Query: 110 GENSGRLYLNPGKK-------RGGLWWTYVCSLVFKASVDIAFLYVFHSFYPKYILPPVV 162
           G + G +  + G K        G L  TY+C ++FK   ++ F+ V H F   + + P+ 
Sbjct: 123 GPDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFI-VGHYFLYGFRILPLY 181

Query: 163 KCHADPCPNIVDCFISKPSEKNIFTLFMVATAAICILLNLVELIYLVSKRCHECL 217
           +C   PCPN+VDCF+S+P+EK IF LFM++ A++ + LN++EL +L  K     L
Sbjct: 182 RCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSAL 236


>gi|62865885 connexin 37 [Homo sapiens]
          Length = 333

 Score =  189 bits (480), Expect = 2e-48
 Identities = 95/250 (38%), Positives = 143/250 (57%), Gaps = 34/250 (13%)

Query: 2   NWSIFEGLLSGVNKYSTAFGRIWLSLVFIFRVLVYLVTAERVWSDDHKDFDCNTRQPGCS 61
           +W   E LL  V ++ST  G+IWL+++FIFR+L+  +  E VW D+  DF+CNT QPGC+
Sbjct: 3   DWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPGCT 62

Query: 62  NVCFDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYREVQEKRHREAHGE---------- 111
           NVC+D+ FP+SH+R W LQ + V+ P+L+ + HV Y   +E+R R+  GE          
Sbjct: 63  NVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKDPQ 122

Query: 112 ------------------NSGRLYLNPGKKRGGLWWTYVCSLVFKASVDIAFLYVFHSFY 153
                               GRL +     RG L  TYV S++ K+ ++  FLY     Y
Sbjct: 123 VERALAAVERQMAKISVAEDGRLRI-----RGALMGTYVASVLCKSVLEAGFLYGQWRLY 177

Query: 154 PKYILPPVVKCHADPCPNIVDCFISKPSEKNIFTLFMVATAAICILLNLVELIYLVSKRC 213
             + + PV  C   PCP +VDCF+S+P+EK IF +FM+    I ++LNL+EL++L+ +  
Sbjct: 178 -GWTMEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCL 236

Query: 214 HECLAARKAQ 223
              + AR+ Q
Sbjct: 237 SRGMRARQGQ 246


>gi|22779877 connexin 46 [Homo sapiens]
          Length = 435

 Score =  184 bits (466), Expect = 9e-47
 Identities = 93/236 (39%), Positives = 140/236 (59%), Gaps = 18/236 (7%)

Query: 2   NWSIFEGLLSGVNKYSTAFGRIWLSLVFIFRVLVYLVTAERVWSDDHKDFDCNTRQPGCS 61
           +WS    LL    ++ST  G++WL+++FIFR+LV    AE VW D+  DF CNT+QPGC 
Sbjct: 3   DWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPGCE 62

Query: 62  NVCFDEFFPVSHVRLWALQLILVTCPSLLVVMHVAY----------REVQEKRHREA--- 108
           NVC+D  FP+SH+R WALQ+I V+ P+L+ + HV +          RE +E+  RE+   
Sbjct: 63  NVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKEREEEEQLKRESPSP 122

Query: 109 ----HGENSGRLYLNPGKKRGGLWWTYVCSLVFKASVDIAFLYVFHSFYPKYILPPVVKC 164
                   S R      +  G L  TYV +++FK   ++ F+   +  Y  + L P+ +C
Sbjct: 123 KEPPQDNPSSRDDRGRVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLY-GFELKPLYRC 181

Query: 165 HADPCPNIVDCFISKPSEKNIFTLFMVATAAICILLNLVELIYLVSKRCHECLAAR 220
              PCPN VDCFIS+P+EK IF +FM+A A   +LLN++E+ +L  K+  + + +R
Sbjct: 182 DRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKKLKQGVTSR 237


>gi|4504001 connexin 43 [Homo sapiens]
          Length = 382

 Score =  181 bits (458), Expect = 8e-46
 Identities = 93/233 (39%), Positives = 134/233 (57%), Gaps = 24/233 (10%)

Query: 2   NWSIFEGLLSGVNKYSTAFGRIWLSLVFIFRVLVYLVTAERVWSDDHKDFDCNTRQPGCS 61
           +WS    LL  V  YSTA G++WLS++FIFR+L+     E  W D+   F CNT+QPGC 
Sbjct: 3   DWSALGKLLDKVQAYSTAGGKVWLSVLFIFRILLLGTAVESAWGDEQSAFRCNTQQPGCE 62

Query: 62  NVCFDEFFPVSHVRLWALQLILVTCPSLLVVMHVAY---------REVQEKRHREAHGEN 112
           NVC+D+ FP+SHVR W LQ+I V+ P+LL + HV Y         ++ +E +  +  G N
Sbjct: 63  NVCYDKSFPISHVRFWVLQIIFVSVPTLLYLAHVFYVMRKEEKLNKKEEELKVAQTDGVN 122

Query: 113 --------------SGRLYLNPGKKRGGLWWTYVCSLVFKASVDIAFLYVFHSFYPKYIL 158
                          G       K RGGL  TY+ S++FK+  ++AFL +    Y  + L
Sbjct: 123 VDMHLKQIEIKKFKYGIEEHGKVKMRGGLLRTYIISILFKSIFEVAFLLIQWYIY-GFSL 181

Query: 159 PPVVKCHADPCPNIVDCFISKPSEKNIFTLFMVATAAICILLNLVELIYLVSK 211
             V  C  DPCP+ VDCF+S+P+EK IF +FM+  + + + LN++EL Y+  K
Sbjct: 182 SAVYTCKRDPCPHQVDCFLSRPTEKTIFIIFMLVVSLVSLALNIIELFYVFFK 234


>gi|14211941 gap junction protein, alpha 10 [Homo sapiens]
          Length = 543

 Score =  177 bits (449), Expect = 9e-45
 Identities = 93/237 (39%), Positives = 140/237 (59%), Gaps = 36/237 (15%)

Query: 2   NWSIFEGLLSGVNKYSTAFGRIWLSLVFIFRVLVYLVTAERVWSDDHKDFDCNTRQPGCS 61
           +W++  G+L  V+ +ST  G+IWL+++FIFR+LV  V AE VW D+   F CNTRQPGC+
Sbjct: 3   DWNLLGGILEEVHSHSTIVGKIWLTILFIFRMLVLRVAAEDVWDDEQSAFACNTRQPGCN 62

Query: 62  NVCFDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYR-------EVQEKRHREAHGEN-- 112
           N+C+D+ FP+S +R W LQ+I V+ PSL+ + H  YR         ++K H  A  EN  
Sbjct: 63  NICYDDAFPISLIRFWVLQIIFVSSPSLVYMGHALYRLRAFEKDRQRKKSHLRAQMENPD 122

Query: 113 ------------------SGRLYLNPGKKRGGLWWTYVCSLVFKASVDIAFL---YVFHS 151
                               R++  P K  G L  TYV  ++ ++ +++ F+   Y+ + 
Sbjct: 123 LDLEEQQRIDRELRRLEEQKRIHKVPLK--GCLLRTYVLHILTRSVLEVGFMIGQYILYG 180

Query: 152 FYPKYILPPVVKCHADPCPNIVDCFISKPSEKNIFTLFMVATAAICILLNLVELIYL 208
           F     + P+ KC   PCPN VDCF+S+P+EK IF LFM + AAI +LLN++E+ +L
Sbjct: 181 FQ----MHPLYKCTQPPCPNAVDCFVSRPTEKTIFMLFMHSIAAISLLLNILEIFHL 233


>gi|31542845 gap junction protein, alpha 9, 59kDa [Homo sapiens]
          Length = 515

 Score =  176 bits (447), Expect = 1e-44
 Identities = 93/239 (38%), Positives = 138/239 (57%), Gaps = 32/239 (13%)

Query: 2   NWSIFEGLLSGVNKYSTAFGRIWLSLVFIFRVLVYLVTAERVWSDDHKDFDCNTRQPGCS 61
           +W++    L  V+ +ST  G+IWL+++FIFR+LV  V AE VW+D+   F CNT QPGC 
Sbjct: 3   DWNLLGDTLEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPGCR 62

Query: 62  NVCFDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYR--------------------EVQ 101
           NVC+D+ FP+S +R W LQ+I V+ PSL+ + H  YR                    EV+
Sbjct: 63  NVCYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEEERQRMKAQLRVELEEVE 122

Query: 102 -----EKRHREAHGENSGRLYLNPGKKRGGLWWTYVCSLVFKASVDIAFL---YVFHSFY 153
                ++R  E       +  LN    RG L  TYV  +  ++ V++ F+   Y+ + F+
Sbjct: 123 FEMPRDRRRLEQELCQLEKRKLNKAPLRGTLLCTYVIHIFTRSVVEVGFMIGQYLLYGFH 182

Query: 154 PKYILPPVVKCHADPCPNIVDCFISKPSEKNIFTLFMVATAAICILLNLVELIYLVSKR 212
               L P+ KCH  PCPNI+DCF+S+P+EK IF LFM + A I + LN++E+ +L  K+
Sbjct: 183 ----LEPLFKCHGHPCPNIIDCFVSRPTEKTIFLLFMQSIATISLFLNILEIFHLGFKK 237


>gi|32483412 connexin 40 [Homo sapiens]
          Length = 358

 Score =  174 bits (441), Expect = 7e-44
 Identities = 98/265 (36%), Positives = 149/265 (56%), Gaps = 34/265 (12%)

Query: 2   NWSIFEGLLSGVNKYSTAFGRIWLSLVFIFRVLVYLVTAERVWSDDHKDFDCNTRQPGCS 61
           +WS     L  V+K+ST  G++WL+++FIFR+LV    AE  W D+  DF C+T QPGC 
Sbjct: 3   DWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQ 62

Query: 62  NVCFDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYR-EVQEKRH-------REAHG--- 110
           NVC+D+ FP+SH+R W LQ+I V+ PSL+ + H  +   +QEKR        +E  G   
Sbjct: 63  NVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGSGS 122

Query: 111 ---------------ENSGRLYLNPGKKRGGLWWTYVCSLVFKASVDIAFLYVFHSFYPK 155
                          E +GR+ L     +G L  TYVCS++ + ++++ F+ V   F   
Sbjct: 123 YEYPVAEKAELSCWEEGNGRIAL-----QGTLLNTYVCSILIRTTMEVGFI-VGQYFIYG 176

Query: 156 YILPPVVKCHADPCPNIVDCFISKPSEKNIFTLFMVATAAICILLNLVELIYLVSKRCHE 215
             L  +  C   PCP+ V+C++S+P+EKN+F +FM+A AA+ +LL+L EL +L  K+  +
Sbjct: 177 IFLTTLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQ 236

Query: 216 -CLAARKAQAMCTGHHPH-GTTSSC 238
             +  R+  A C    P  G   SC
Sbjct: 237 RFVKPRQHMAKCQLSGPSVGIVQSC 261


>gi|6631083 connexin 40 [Homo sapiens]
          Length = 358

 Score =  174 bits (441), Expect = 7e-44
 Identities = 98/265 (36%), Positives = 149/265 (56%), Gaps = 34/265 (12%)

Query: 2   NWSIFEGLLSGVNKYSTAFGRIWLSLVFIFRVLVYLVTAERVWSDDHKDFDCNTRQPGCS 61
           +WS     L  V+K+ST  G++WL+++FIFR+LV    AE  W D+  DF C+T QPGC 
Sbjct: 3   DWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQ 62

Query: 62  NVCFDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYR-EVQEKRH-------REAHG--- 110
           NVC+D+ FP+SH+R W LQ+I V+ PSL+ + H  +   +QEKR        +E  G   
Sbjct: 63  NVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGSGS 122

Query: 111 ---------------ENSGRLYLNPGKKRGGLWWTYVCSLVFKASVDIAFLYVFHSFYPK 155
                          E +GR+ L     +G L  TYVCS++ + ++++ F+ V   F   
Sbjct: 123 YEYPVAEKAELSCWEEGNGRIAL-----QGTLLNTYVCSILIRTTMEVGFI-VGQYFIYG 176

Query: 156 YILPPVVKCHADPCPNIVDCFISKPSEKNIFTLFMVATAAICILLNLVELIYLVSKRCHE 215
             L  +  C   PCP+ V+C++S+P+EKN+F +FM+A AA+ +LL+L EL +L  K+  +
Sbjct: 177 IFLTTLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQ 236

Query: 216 -CLAARKAQAMCTGHHPH-GTTSSC 238
             +  R+  A C    P  G   SC
Sbjct: 237 RFVKPRQHMAKCQLSGPSVGIVQSC 261


>gi|122939172 connexin 45 [Homo sapiens]
          Length = 396

 Score =  144 bits (362), Expect = 1e-34
 Identities = 81/254 (31%), Positives = 129/254 (50%), Gaps = 47/254 (18%)

Query: 1   MNWSIFEGLLSGVNKYSTAFGRIWLSLVFIFRVLVYLVTAERVWSDDHKDFDCNTRQPGC 60
           M+WS    LL  ++ +ST  G+IWL+++ +FR+++  V  E ++ D+   F CNT QPGC
Sbjct: 1   MSWSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPGC 60

Query: 61  SNVCFDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYR-------------------EVQ 101
            NVC+D F P+SHVR W  Q+ILV  PS++ + +  ++                    ++
Sbjct: 61  ENVCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPYAMR 120

Query: 102 EKRHR---------------------EAHGENSGRLYLNP---GKKR---GGLWWTYVCS 134
            K+HR                     E+  EN  +    P   G++R    GL   YV  
Sbjct: 121 WKQHRALEETEEDNEEDPMMYPEMELESDKENKEQSQPKPKHDGRRRIREDGLMKIYVLQ 180

Query: 135 LVFKASVDIAFLYVFHSFYPKYILPPVVKCHADPCPNIVDCFISKPSEKNIFTLFMVATA 194
           L+ +   ++ FL +   F   + + P   C   PCP+ +DCFIS+P+EK IF L M    
Sbjct: 181 LLARTVFEVGFL-IGQYFLYGFQVHPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGVT 239

Query: 195 AICILLNLVELIYL 208
            +C+LLN+ E+++L
Sbjct: 240 GLCLLLNIWEMLHL 253


>gi|69122473 connexin 45 [Homo sapiens]
          Length = 396

 Score =  144 bits (362), Expect = 1e-34
 Identities = 81/254 (31%), Positives = 129/254 (50%), Gaps = 47/254 (18%)

Query: 1   MNWSIFEGLLSGVNKYSTAFGRIWLSLVFIFRVLVYLVTAERVWSDDHKDFDCNTRQPGC 60
           M+WS    LL  ++ +ST  G+IWL+++ +FR+++  V  E ++ D+   F CNT QPGC
Sbjct: 1   MSWSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPGC 60

Query: 61  SNVCFDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYR-------------------EVQ 101
            NVC+D F P+SHVR W  Q+ILV  PS++ + +  ++                    ++
Sbjct: 61  ENVCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPYAMR 120

Query: 102 EKRHR---------------------EAHGENSGRLYLNP---GKKR---GGLWWTYVCS 134
            K+HR                     E+  EN  +    P   G++R    GL   YV  
Sbjct: 121 WKQHRALEETEEDNEEDPMMYPEMELESDKENKEQSQPKPKHDGRRRIREDGLMKIYVLQ 180

Query: 135 LVFKASVDIAFLYVFHSFYPKYILPPVVKCHADPCPNIVDCFISKPSEKNIFTLFMVATA 194
           L+ +   ++ FL +   F   + + P   C   PCP+ +DCFIS+P+EK IF L M    
Sbjct: 181 LLARTVFEVGFL-IGQYFLYGFQVHPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGVT 239

Query: 195 AICILLNLVELIYL 208
            +C+LLN+ E+++L
Sbjct: 240 GLCLLLNIWEMLHL 253


>gi|148839378 gap junction protein, delta 3, 31.9kDa [Homo sapiens]
          Length = 294

 Score =  129 bits (325), Expect = 2e-30
 Identities = 72/217 (33%), Positives = 111/217 (51%), Gaps = 13/217 (5%)

Query: 3   WSIFEGLLSGVNKYSTAFGRIWLSLVFIFRVLVYLVTAERVWSDDHKDFDCNTRQPGCSN 62
           W+    LL  V   S   GR+WL ++ IFR+LV       V+ D+ ++F CNT QPGC  
Sbjct: 4   WAFLGSLLDAVQLQSPLVGRLWLVVMLIFRILVLATVGGAVFEDEQEEFVCNTLQPGCRQ 63

Query: 63  VCFDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYREVQEKRHREAHGENSGRL------ 116
            C+D  FPVSH R W   ++L++ P +L V++  +R  +E    EA  + +  L      
Sbjct: 64  TCYDRAFPVSHYRFWLFHILLLSAPPVLFVVYSMHRAGKEAGGAEAAAQCAPGLPEAQCA 123

Query: 117 --YLNPGKKRGGLWWTYVCSLVFKASVDIAFLYVFHSFYPKYILPPVVKCHADPCPNIVD 174
              L   + R      Y+ S+  +   ++ FL      Y  + + P   C   PCP+ VD
Sbjct: 124 PCALRARRARR----CYLLSVALRLLAELTFLGGQALLY-GFRVAPHFACAGPPCPHTVD 178

Query: 175 CFISKPSEKNIFTLFMVATAAICILLNLVELIYLVSK 211
           CF+S+P+EK +F LF  A   +  LL++ EL +L+ K
Sbjct: 179 CFVSRPTEKTVFVLFYFAVGLLSALLSVAELGHLLWK 215


>gi|145699105 connexin40.1 [Homo sapiens]
          Length = 370

 Score =  126 bits (317), Expect = 2e-29
 Identities = 71/215 (33%), Positives = 116/215 (53%), Gaps = 12/215 (5%)

Query: 9   LLSGVNKYSTAFGRIWLSLVFIFRVLVYLVTAERVWSDDHKDFDCNTRQPGCSNVCFDEF 68
           L+  +N   T  G++W  L  + R+LV ++    V+ D+ + F CNT QPGC+NVC+D F
Sbjct: 10  LIITLNCNVTMVGKLWFVLTMLLRMLVIVLAGRPVYQDEQERFVCNTLQPGCANVCYDVF 69

Query: 69  FPVSHVRLWALQLILVTCPSLLVVMHVAYR-----EVQEKRHREAHGENSG-RLYLNPGK 122
            PVSH+R W +Q + V  PS +  ++V +R      +  +R  +     SG R    P  
Sbjct: 70  SPVSHLRFWLIQGVCVLLPSAVFSVYVLHRGATLAALGPRRCPDPREPASGQRRCPRPFG 129

Query: 123 KRGGLWWT-----YVCSLVFKASVDIAFLYVFHSFYPKYILPPVVKCHADPCPNIVDCFI 177
           +RGGL        Y+  L+ +  ++ AF    H F   ++ P    C   PC  +VDC++
Sbjct: 130 ERGGLQVPDFSAGYIIHLLLRTLLEAAF-GALHYFLFGFLAPKKFPCTRPPCTGVVDCYV 188

Query: 178 SKPSEKNIFTLFMVATAAICILLNLVELIYLVSKR 212
           S+P+EK++  LF+ A +A+  LL L +L+  + +R
Sbjct: 189 SRPTEKSLLMLFLWAVSALSFLLGLADLVCSLRRR 223


>gi|31559821 gap junction protein, gamma 3, 30.2kDa [Homo sapiens]
          Length = 279

 Score =  111 bits (277), Expect = 8e-25
 Identities = 65/209 (31%), Positives = 103/209 (49%), Gaps = 13/209 (6%)

Query: 9   LLSGVNKYSTAFGRIWLSLVFIFRVLVYLVTAERVWSDDHKDFDCNTRQPGCSNVCFDEF 68
           LL+  ++ ST  GR+ L ++  FR+++   +   V+ D+  +F C+T+QPGC   CFD F
Sbjct: 9   LLAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACFDAF 68

Query: 69  FPVSHVRLWALQLILVTCPSLLVVMHVAYREVQEKRHREAHGENSGRLYLNPGKKRG--- 125
            P+S +R W  Q+ILV  PS L +    Y  +    H E  G+      L  G++     
Sbjct: 69  HPLSPLRFWVFQVILVAVPSALYMGFTLYHVIW---HWELSGKGKEEETLIQGREGNTDV 125

Query: 126 ------GLWWTYVCSLVFKASVDIAFLYVFHSFYPKYILPPVVKCHADPCPNIVDCFISK 179
                  L W YV  L  +  ++ A L + +  Y  + +P    C  +PC   + C +S+
Sbjct: 126 PGAGSLRLLWAYVAQLGARLVLEGAALGLQYHLY-GFQMPSSFACRREPCLGSITCNLSR 184

Query: 180 PSEKNIFTLFMVATAAICILLNLVELIYL 208
           PSEK IF   M   +  C+L   +EL+ L
Sbjct: 185 PSEKTIFLKTMFGVSGFCLLFTFLELVLL 213


>gi|45439367 gap junction protein, gamma 2, 47kDa [Homo sapiens]
          Length = 439

 Score =  107 bits (267), Expect = 1e-23
 Identities = 46/124 (37%), Positives = 76/124 (61%), Gaps = 5/124 (4%)

Query: 1   MNWSIFEGLLSGVNKYSTAFGRIWLSLVFIFRVLVYLVTAERVWSDDHKDFDCNTRQPGC 60
           M+WS    LL  ++ +ST  G++WL+++ +FR+++  V  E ++SD+   F CNTRQPGC
Sbjct: 4   MSWSFLTRLLEEIHNHSTFVGKVWLTVLVVFRIVLTAVGGEAIYSDEQAKFTCNTRQPGC 63

Query: 61  SNVCFDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYREVQEKRHREAHGENSGRLYLNP 120
            NVC+D F P+SHVR W  Q+++++ PS++ + +  +R       R +  E    L   P
Sbjct: 64  DNVCYDAFAPLSHVRFWVFQIVVISTPSVMYLGYAVHRLA-----RASEQERRRALRRRP 118

Query: 121 GKKR 124
           G +R
Sbjct: 119 GPRR 122



 Score = 77.4 bits (189), Expect = 1e-14
 Identities = 39/112 (34%), Positives = 64/112 (57%), Gaps = 5/112 (4%)

Query: 110 GENSGRLYLNPGKKRGGLWWTYVCSLVFKASVDIAFLYVFHSFYPKYILPPVVKCHADPC 169
           G++ GR  +    +R GL   YV  LV +A+ ++AFL   +  Y  + + P   C   PC
Sbjct: 196 GQHDGRRRI----QREGLMRVYVAQLVARAAFEVAFLVGQYLLYG-FEVRPFFPCSRQPC 250

Query: 170 PNIVDCFISKPSEKNIFTLFMVATAAICILLNLVELIYLVSKRCHECLAARK 221
           P++VDCF+S+P+EK +F L M   + +C+LLNL E+ +L      + +  R+
Sbjct: 251 PHVVDCFVSRPTEKTVFLLVMYVVSCLCLLLNLCEMAHLGLGSAQDAVRGRR 302


>gi|10190698 gap junction protein, delta 2, 36kDa [Homo sapiens]
          Length = 321

 Score = 99.8 bits (247), Expect = 2e-21
 Identities = 43/105 (40%), Positives = 67/105 (63%), Gaps = 1/105 (0%)

Query: 3   WSIFEGLL-SGVNKYSTAFGRIWLSLVFIFRVLVYLVTAERVWSDDHKDFDCNTRQPGCS 61
           W+I E LL + V ++ST  GRI L++V IFR+L+  +  E V+ D+   F CNT QPGC+
Sbjct: 4   WTILERLLEAAVQQHSTMIGRILLTVVVIFRILIVAIVGETVYDDEQTMFVCNTLQPGCN 63

Query: 62  NVCFDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYREVQEKRHR 106
             C+D  FP+SH+R W  Q+I+V  PSL  + +  ++  +++  R
Sbjct: 64  QACYDRAFPISHIRYWVFQIIMVCTPSLCFITYSVHQSAKQRERR 108



 Score = 70.5 bits (171), Expect = 2e-12
 Identities = 37/103 (35%), Positives = 65/103 (63%), Gaps = 3/103 (2%)

Query: 122 KKRGGLWWTYVCSLVFKASVDIAFLYVFHSFYPKYILPPVVKCHADPCPNIVDCFISKPS 181
           +++ G+   Y+  +VF+ +++I FL V   F   + +P + +C+  PC   V+C++S+P+
Sbjct: 190 RRQEGISRFYIIQVVFRNALEIGFL-VGQYFLYGFSVPGLYECNRYPCIKEVECYVSRPT 248

Query: 182 EKNIFTLFMVATAAICILLNLVELIYLVSKRCHECLAARKAQA 224
           EK +F +FM A + IC++LNL EL +L  ++    LA R AQA
Sbjct: 249 EKTVFLVFMFAVSGICVVLNLAELNHLGWRKIK--LAVRGAQA 289


>gi|169171704 PREDICTED: similar to hCG1770601 [Homo sapiens]
          Length = 222

 Score = 72.0 bits (175), Expect = 5e-13
 Identities = 32/82 (39%), Positives = 51/82 (62%)

Query: 9   LLSGVNKYSTAFGRIWLSLVFIFRVLVYLVTAERVWSDDHKDFDCNTRQPGCSNVCFDEF 68
           LL+  + +ST  GR+   ++  FR+++   +   V+ D+  +F C+T+QPGC   CFD F
Sbjct: 28  LLAEESWHSTPVGRLLFPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACFDAF 87

Query: 69  FPVSHVRLWALQLILVTCPSLL 90
            P+S +R W  Q+ILV  PS+L
Sbjct: 88  HPLSPLRFWVFQVILVAVPSVL 109


>gi|169171845 PREDICTED: similar to hCG1770601 [Homo sapiens]
          Length = 222

 Score = 72.0 bits (175), Expect = 5e-13
 Identities = 32/82 (39%), Positives = 51/82 (62%)

Query: 9   LLSGVNKYSTAFGRIWLSLVFIFRVLVYLVTAERVWSDDHKDFDCNTRQPGCSNVCFDEF 68
           LL+  + +ST  GR+   ++  FR+++   +   V+ D+  +F C+T+QPGC   CFD F
Sbjct: 28  LLAEESWHSTPVGRLLFPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACFDAF 87

Query: 69  FPVSHVRLWALQLILVTCPSLL 90
            P+S +R W  Q+ILV  PS+L
Sbjct: 88  HPLSPLRFWVFQVILVAVPSVL 109


>gi|169171183 PREDICTED: similar to hCG1770601 [Homo sapiens]
          Length = 222

 Score = 72.0 bits (175), Expect = 5e-13
 Identities = 32/82 (39%), Positives = 51/82 (62%)

Query: 9   LLSGVNKYSTAFGRIWLSLVFIFRVLVYLVTAERVWSDDHKDFDCNTRQPGCSNVCFDEF 68
           LL+  + +ST  GR+   ++  FR+++   +   V+ D+  +F C+T+QPGC   CFD F
Sbjct: 28  LLAEESWHSTPVGRLLFPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACFDAF 87

Query: 69  FPVSHVRLWALQLILVTCPSLL 90
            P+S +R W  Q+ILV  PS+L
Sbjct: 88  HPLSPLRFWVFQVILVAVPSVL 109


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.327    0.141    0.468 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,517,279
Number of Sequences: 37866
Number of extensions: 500641
Number of successful extensions: 1340
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1273
Number of HSP's gapped (non-prelim): 47
length of query: 273
length of database: 18,247,518
effective HSP length: 101
effective length of query: 172
effective length of database: 14,423,052
effective search space: 2480764944
effective search space used: 2480764944
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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