Guide to the Human Genome
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Search of human proteins with 239747548

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239747548 PREDICTED: achaete-scute complex homolog 5
(Drosophila) [Homo sapiens]
         (313 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239752994 PREDICTED: achaete-scute complex homolog 5 (Drosoph...   664   0.0  
gi|239747548 PREDICTED: achaete-scute complex homolog 5 (Drosoph...   664   0.0  
gi|239741422 PREDICTED: achaete-scute complex homolog 5 [Homo sa...   664   0.0  
gi|206597481 achaete-scute complex-like 4 [Homo sapiens]              109   4e-24
gi|10190680 ASCL3 [Homo sapiens]                                      106   3e-23
gi|4885665 achaete-scute complex homolog-like 2 [Homo sapiens]         88   1e-17
gi|55743094 achaete-scute complex homolog 1 [Homo sapiens]             75   7e-14
gi|239756681 PREDICTED: basic helix-loop-helix family, member a9...    60   3e-09
gi|30039710 pancreas specific transcription factor, 1a [Homo sap...    59   4e-09
gi|239751178 PREDICTED: basic helix-loop-helix family, member a9...    59   6e-09
gi|239745666 PREDICTED: basic helix-loop-helix family, member a9...    59   6e-09
gi|34147558 lymphoblastic leukemia derived sequence 1 [Homo sapi...    58   1e-08
gi|148922889 scleraxis homolog B [Homo sapiens]                        55   8e-08
gi|186972126 scleraxis homolog A [Homo sapiens]                        55   8e-08
gi|12545384 basic helix-loop-helix transcription factor HAND2 [H...    54   2e-07
gi|23097242 nephew of atonal 3 [Homo sapiens]                          53   3e-07
gi|29126247 basic helix-loop-helix family, member a15 [Homo sapi...    53   4e-07
gi|38455396 neurogenin 1 [Homo sapiens]                                51   1e-06
gi|4758506 basic helix-loop-helix transcription factor HAND1 [Ho...    51   1e-06
gi|23111009 myogenic differentiation 1 [Homo sapiens]                  50   2e-06
gi|17981708 twist homolog 2 [Homo sapiens]                             50   3e-06
gi|4885619 T-cell acute lymphocytic leukemia 2 [Homo sapiens]          50   3e-06
gi|4885075 atonal homolog 1 [Homo sapiens]                             49   4e-06
gi|4507363 T-cell acute lymphocytic leukemia 1 [Homo sapiens]          49   4e-06
gi|4507741 twist [Homo sapiens]                                        49   6e-06
gi|116517330 factor in the germline alpha [Homo sapiens]               49   6e-06
gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]         48   1e-05
gi|119508426 alpha 3 type IX collagen [Homo sapiens]                   48   1e-05
gi|48255909 basic helix-loop-helix transcription factor 15 [Homo...    48   1e-05
gi|6382071 diaphanous 2 isoform 12C [Homo sapiens]                     47   2e-05

>gi|239752994 PREDICTED: achaete-scute complex homolog 5
           (Drosophila) [Homo sapiens]
          Length = 313

 Score =  664 bits (1714), Expect = 0.0
 Identities = 313/313 (100%), Positives = 313/313 (100%)

Query: 1   MSAPLAFSLRTNWQESWKKARPEAAEGAAGQAGSPGDSAVPPGGSRATDQDKRCRRNKPR 60
           MSAPLAFSLRTNWQESWKKARPEAAEGAAGQAGSPGDSAVPPGGSRATDQDKRCRRNKPR
Sbjct: 1   MSAPLAFSLRTNWQESWKKARPEAAEGAAGQAGSPGDSAVPPGGSRATDQDKRCRRNKPR 60

Query: 61  EKCSRGLPPLSWRTPNSSHQFGDPGQPGDPEGREDQGPGAGVAPRGTMNNNFCRALVDRR 120
           EKCSRGLPPLSWRTPNSSHQFGDPGQPGDPEGREDQGPGAGVAPRGTMNNNFCRALVDRR
Sbjct: 61  EKCSRGLPPLSWRTPNSSHQFGDPGQPGDPEGREDQGPGAGVAPRGTMNNNFCRALVDRR 120

Query: 121 PLGPPSCMQLGVMPPPRQAPLPPAEPLGNVPFLLYPGPAEPPYYDAYAGVFPYVPFPGAF 180
           PLGPPSCMQLGVMPPPRQAPLPPAEPLGNVPFLLYPGPAEPPYYDAYAGVFPYVPFPGAF
Sbjct: 121 PLGPPSCMQLGVMPPPRQAPLPPAEPLGNVPFLLYPGPAEPPYYDAYAGVFPYVPFPGAF 180

Query: 181 GVYEYPFEPAFIQKRNERERQRVKCVNEGYARLRGHLPGALAEKRLSKVETLRAAIRYIK 240
           GVYEYPFEPAFIQKRNERERQRVKCVNEGYARLRGHLPGALAEKRLSKVETLRAAIRYIK
Sbjct: 181 GVYEYPFEPAFIQKRNERERQRVKCVNEGYARLRGHLPGALAEKRLSKVETLRAAIRYIK 240

Query: 241 YLQELLSSAPDGSTPPASRGLPGTGPCPAPPATPRPDRPGDGEARAPSSLVPESSESSCF 300
           YLQELLSSAPDGSTPPASRGLPGTGPCPAPPATPRPDRPGDGEARAPSSLVPESSESSCF
Sbjct: 241 YLQELLSSAPDGSTPPASRGLPGTGPCPAPPATPRPDRPGDGEARAPSSLVPESSESSCF 300

Query: 301 SPSPFLESEESWH 313
           SPSPFLESEESWH
Sbjct: 301 SPSPFLESEESWH 313


>gi|239747548 PREDICTED: achaete-scute complex homolog 5
           (Drosophila) [Homo sapiens]
          Length = 313

 Score =  664 bits (1714), Expect = 0.0
 Identities = 313/313 (100%), Positives = 313/313 (100%)

Query: 1   MSAPLAFSLRTNWQESWKKARPEAAEGAAGQAGSPGDSAVPPGGSRATDQDKRCRRNKPR 60
           MSAPLAFSLRTNWQESWKKARPEAAEGAAGQAGSPGDSAVPPGGSRATDQDKRCRRNKPR
Sbjct: 1   MSAPLAFSLRTNWQESWKKARPEAAEGAAGQAGSPGDSAVPPGGSRATDQDKRCRRNKPR 60

Query: 61  EKCSRGLPPLSWRTPNSSHQFGDPGQPGDPEGREDQGPGAGVAPRGTMNNNFCRALVDRR 120
           EKCSRGLPPLSWRTPNSSHQFGDPGQPGDPEGREDQGPGAGVAPRGTMNNNFCRALVDRR
Sbjct: 61  EKCSRGLPPLSWRTPNSSHQFGDPGQPGDPEGREDQGPGAGVAPRGTMNNNFCRALVDRR 120

Query: 121 PLGPPSCMQLGVMPPPRQAPLPPAEPLGNVPFLLYPGPAEPPYYDAYAGVFPYVPFPGAF 180
           PLGPPSCMQLGVMPPPRQAPLPPAEPLGNVPFLLYPGPAEPPYYDAYAGVFPYVPFPGAF
Sbjct: 121 PLGPPSCMQLGVMPPPRQAPLPPAEPLGNVPFLLYPGPAEPPYYDAYAGVFPYVPFPGAF 180

Query: 181 GVYEYPFEPAFIQKRNERERQRVKCVNEGYARLRGHLPGALAEKRLSKVETLRAAIRYIK 240
           GVYEYPFEPAFIQKRNERERQRVKCVNEGYARLRGHLPGALAEKRLSKVETLRAAIRYIK
Sbjct: 181 GVYEYPFEPAFIQKRNERERQRVKCVNEGYARLRGHLPGALAEKRLSKVETLRAAIRYIK 240

Query: 241 YLQELLSSAPDGSTPPASRGLPGTGPCPAPPATPRPDRPGDGEARAPSSLVPESSESSCF 300
           YLQELLSSAPDGSTPPASRGLPGTGPCPAPPATPRPDRPGDGEARAPSSLVPESSESSCF
Sbjct: 241 YLQELLSSAPDGSTPPASRGLPGTGPCPAPPATPRPDRPGDGEARAPSSLVPESSESSCF 300

Query: 301 SPSPFLESEESWH 313
           SPSPFLESEESWH
Sbjct: 301 SPSPFLESEESWH 313


>gi|239741422 PREDICTED: achaete-scute complex homolog 5 [Homo
           sapiens]
          Length = 313

 Score =  664 bits (1714), Expect = 0.0
 Identities = 313/313 (100%), Positives = 313/313 (100%)

Query: 1   MSAPLAFSLRTNWQESWKKARPEAAEGAAGQAGSPGDSAVPPGGSRATDQDKRCRRNKPR 60
           MSAPLAFSLRTNWQESWKKARPEAAEGAAGQAGSPGDSAVPPGGSRATDQDKRCRRNKPR
Sbjct: 1   MSAPLAFSLRTNWQESWKKARPEAAEGAAGQAGSPGDSAVPPGGSRATDQDKRCRRNKPR 60

Query: 61  EKCSRGLPPLSWRTPNSSHQFGDPGQPGDPEGREDQGPGAGVAPRGTMNNNFCRALVDRR 120
           EKCSRGLPPLSWRTPNSSHQFGDPGQPGDPEGREDQGPGAGVAPRGTMNNNFCRALVDRR
Sbjct: 61  EKCSRGLPPLSWRTPNSSHQFGDPGQPGDPEGREDQGPGAGVAPRGTMNNNFCRALVDRR 120

Query: 121 PLGPPSCMQLGVMPPPRQAPLPPAEPLGNVPFLLYPGPAEPPYYDAYAGVFPYVPFPGAF 180
           PLGPPSCMQLGVMPPPRQAPLPPAEPLGNVPFLLYPGPAEPPYYDAYAGVFPYVPFPGAF
Sbjct: 121 PLGPPSCMQLGVMPPPRQAPLPPAEPLGNVPFLLYPGPAEPPYYDAYAGVFPYVPFPGAF 180

Query: 181 GVYEYPFEPAFIQKRNERERQRVKCVNEGYARLRGHLPGALAEKRLSKVETLRAAIRYIK 240
           GVYEYPFEPAFIQKRNERERQRVKCVNEGYARLRGHLPGALAEKRLSKVETLRAAIRYIK
Sbjct: 181 GVYEYPFEPAFIQKRNERERQRVKCVNEGYARLRGHLPGALAEKRLSKVETLRAAIRYIK 240

Query: 241 YLQELLSSAPDGSTPPASRGLPGTGPCPAPPATPRPDRPGDGEARAPSSLVPESSESSCF 300
           YLQELLSSAPDGSTPPASRGLPGTGPCPAPPATPRPDRPGDGEARAPSSLVPESSESSCF
Sbjct: 241 YLQELLSSAPDGSTPPASRGLPGTGPCPAPPATPRPDRPGDGEARAPSSLVPESSESSCF 300

Query: 301 SPSPFLESEESWH 313
           SPSPFLESEESWH
Sbjct: 301 SPSPFLESEESWH 313


>gi|206597481 achaete-scute complex-like 4 [Homo sapiens]
          Length = 173

 Score =  109 bits (272), Expect = 4e-24
 Identities = 66/122 (54%), Positives = 77/122 (63%), Gaps = 16/122 (13%)

Query: 173 YVPFPGAFGVYEYPFEPAFIQKRNERERQRVKCVNEGYARLRGHLPGALAEKRLSKVETL 232
           Y+P P      +  FEPAF++KRNERERQRV+CVNEGYARLR HLP  LA+KRLSKVETL
Sbjct: 61  YLPVP-----LDSAFEPAFLRKRNERERQRVRCVNEGYARLRDHLPRELADKRLSKVETL 115

Query: 233 RAAIRYIKYLQELLSSAPDGSTPPASRGLPGTGPCPAPPATPRPDRPGDGEARAPSSLVP 292
           RAAI YIK+LQELL     G       G  G  P        R +   DGE++A S+  P
Sbjct: 116 RAAIDYIKHLQELLERQAWG-----LEGAAGAVP------QRRAECNSDGESKASSAPSP 164

Query: 293 ES 294
            S
Sbjct: 165 SS 166


>gi|10190680 ASCL3 [Homo sapiens]
          Length = 181

 Score =  106 bits (264), Expect = 3e-23
 Identities = 72/160 (45%), Positives = 85/160 (53%), Gaps = 33/160 (20%)

Query: 108 MNNNFCRALVDRRPLGPPSCMQLGVMPPPRQAPLPPAEPLGNVPFLLYPGPAEPPYYDAY 167
           M+N    +L D+ P+ P S      +P  R   L P      V F ++P   E P    Y
Sbjct: 2   MDNRGNSSLPDKLPIFPDSAR----LPLTRSFYLEPM-----VTFHVHP---EAPVSSPY 49

Query: 168 AGVFPYVPFPG---AFGVY------------------EYPFEPAFIQKRNERERQRVKCV 206
           +   P +PFP      G Y                  EY + PAF +KRNERERQRVKCV
Sbjct: 50  SEELPRLPFPSDSLILGNYSEPCPFSFPMPYPNYRGCEYSYGPAFTRKRNERERQRVKCV 109

Query: 207 NEGYARLRGHLPGALAEKRLSKVETLRAAIRYIKYLQELL 246
           NEGYA+LR HLP    EKRLSKVETLRAAI+YI YLQ LL
Sbjct: 110 NEGYAQLRHHLPEEYLEKRLSKVETLRAAIKYINYLQSLL 149


>gi|4885665 achaete-scute complex homolog-like 2 [Homo sapiens]
          Length = 193

 Score = 87.8 bits (216), Expect = 1e-17
 Identities = 55/124 (44%), Positives = 67/124 (54%), Gaps = 15/124 (12%)

Query: 190 AFIQKRNERERQRVKCVNEGYARLRGHLPGALAEKRLSKVETLRAAIRYIKYLQELLSS- 248
           A + +RNERER RVK VN G+  LR H+P   A K+LSKVETLR+A+ YI+ LQ LL+  
Sbjct: 50  AAVARRNERERNRVKLVNLGFQALRQHVPHGGASKKLSKVETLRSAVEYIRALQRLLAEH 109

Query: 249 -----------APDGSTPPASRGLPGTGPCPAPP--ATPRPDRPGDGEARAPSSLVPESS 295
                       P    P A RG PGT P  A P  A+  P R G  E  +P S    S 
Sbjct: 110 DAVRNALAGGLRPQAVRPSAPRGPPGTTPVAASPSRASSSPGRGGSSEPGSPRSAY-SSD 168

Query: 296 ESSC 299
           +S C
Sbjct: 169 DSGC 172


>gi|55743094 achaete-scute complex homolog 1 [Homo sapiens]
          Length = 236

 Score = 75.1 bits (183), Expect = 7e-14
 Identities = 35/59 (59%), Positives = 46/59 (77%)

Query: 188 EPAFIQKRNERERQRVKCVNEGYARLRGHLPGALAEKRLSKVETLRAAIRYIKYLQELL 246
           +PA + +RNERER RVK VN G+A LR H+P   A K++SKVETLR+A+ YI+ LQ+LL
Sbjct: 116 QPAAVARRNERERNRVKLVNLGFATLREHVPNGAANKKMSKVETLRSAVEYIRALQQLL 174


>gi|239756681 PREDICTED: basic helix-loop-helix family, member a9
           [Homo sapiens]
          Length = 203

 Score = 59.7 bits (143), Expect = 3e-09
 Identities = 45/119 (37%), Positives = 56/119 (47%), Gaps = 11/119 (9%)

Query: 196 NERERQRVKCVNEGYARLRGHLPGALAEKRLSKVETLRAAIRYIKYLQELLSSAPDGSTP 255
           N RER+R+   NE +  LR  L   L  KRLSK+ TLR AI  I  L  +L ++P    P
Sbjct: 71  NVRERKRILDYNEAFNALRRALRHDLGGKRLSKIATLRRAIHRIAALSLVLRASPAPRGP 130

Query: 256 --------PASRGLPG-TGPCPAPPATPRPDRPGDGEARAPSSLVPESSESSCFSPSPF 305
                   PA+RG  G TG  P PPA P   RP       PS+  P  +      P P+
Sbjct: 131 CGHLECHGPAARGDTGDTGASPPPPAGPSLARPDAARPSVPSA--PRCASCPPHGPPPW 187


>gi|30039710 pancreas specific transcription factor, 1a [Homo
           sapiens]
          Length = 328

 Score = 59.3 bits (142), Expect = 4e-09
 Identities = 38/90 (42%), Positives = 49/90 (54%), Gaps = 9/90 (10%)

Query: 193 QKRNERERQRVKCVNEGYARLRGHLPGALAEKRLSKVETLRAAIRYIKYLQELLSSAPDG 252
           Q  N RER+R++ +N+ +  LR H+P    EKRLSKV+TLR AI YI +L EL+      
Sbjct: 166 QAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSELVQ----- 220

Query: 253 STPPASRGLPGTGPCPAPPATPR--PDRPG 280
           +  P   G  G G C  P    R   D PG
Sbjct: 221 ADLPLRGG--GAGGCGGPGGGGRLGGDSPG 248


>gi|239751178 PREDICTED: basic helix-loop-helix family, member a9
           [Homo sapiens]
          Length = 235

 Score = 58.9 bits (141), Expect = 6e-09
 Identities = 42/103 (40%), Positives = 51/103 (49%), Gaps = 9/103 (8%)

Query: 196 NERERQRVKCVNEGYARLRGHLPGALAEKRLSKVETLRAAIRYIKYLQELLSSAPDGSTP 255
           N RER+R+   NE +  LR  L   L  KRLSK+ TLR AI  I  L  +L ++P    P
Sbjct: 71  NVRERKRILDYNEAFNALRRALRHDLGGKRLSKIATLRRAIHRIAALSLVLRASPAPRGP 130

Query: 256 --------PASRGLPG-TGPCPAPPATPRPDRPGDGEARAPSS 289
                   PA+RG  G TG  P PPA P   RP       PS+
Sbjct: 131 CGHLECHGPAARGDTGDTGASPPPPAGPSLARPDAARPSVPSA 173


>gi|239745666 PREDICTED: basic helix-loop-helix family, member a9
           [Homo sapiens]
          Length = 235

 Score = 58.9 bits (141), Expect = 6e-09
 Identities = 42/103 (40%), Positives = 51/103 (49%), Gaps = 9/103 (8%)

Query: 196 NERERQRVKCVNEGYARLRGHLPGALAEKRLSKVETLRAAIRYIKYLQELLSSAPDGSTP 255
           N RER+R+   NE +  LR  L   L  KRLSK+ TLR AI  I  L  +L ++P    P
Sbjct: 71  NVRERKRILDYNEAFNALRRALRHDLGGKRLSKIATLRRAIHRIAALSLVLRASPAPRGP 130

Query: 256 --------PASRGLPG-TGPCPAPPATPRPDRPGDGEARAPSS 289
                   PA+RG  G TG  P PPA P   RP       PS+
Sbjct: 131 CGHLECHGPAARGDTGDTGASPPPPAGPSLARPDAARPSVPSA 173


>gi|34147558 lymphoblastic leukemia derived sequence 1 [Homo
           sapiens]
          Length = 280

 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 70/251 (27%), Positives = 95/251 (37%), Gaps = 39/251 (15%)

Query: 84  PGQPGDPEGREDQGPGAGVAPRGTMNNNFCRALVDRRPLGPPSCMQLGVMPPPRQAPLPP 143
           P  PG P+  E    G    PR             R P       +LG + PP    L  
Sbjct: 34  PASPGPPQVEEVGHRGGSSPPRLPPGVPVISLGHSRPPGVAMPTTELGTLRPP----LLQ 89

Query: 144 AEPLGNVPFLL----YPGPAEPPYYDAYAGVFPYVPFPGAFGVYEYP----------FEP 189
              LG  P  L    +P P     Y   AG  P+  FP +  +   P           +P
Sbjct: 90  LSTLGTAPPTLALHYHPHPFLNSVYIGPAG--PFSIFPSS-RLKRRPSHCELDLAEGHQP 146

Query: 190 AFIQKR---NERERQRVKCVNEGYARLRGHLPGALAEKRLSKVETLRAAIRYIKYLQELL 246
             + +R   N RER R + VN  +A LR  LP    +++LSK E LR A++YI +L  LL
Sbjct: 147 QKVARRVFTNSRERWRQQNVNGAFAELRKLLPTHPPDRKLSKNEVLRLAMKYIGFLVRLL 206

Query: 247 ----SSAPDGSTPPASRGLP-----------GTGPCPAPPATPRPDRPGDGEARAPSSLV 291
               ++   G TPP  R  P           G+G      A  +P  P D +     +  
Sbjct: 207 RDQAAALAAGPTPPGPRKRPVHRVPDDGARRGSGRRAEAAARSQPAPPADPDGSPGGAAR 266

Query: 292 PESSESSCFSP 302
           P   E +  SP
Sbjct: 267 PIKMEQTALSP 277


>gi|148922889 scleraxis homolog B [Homo sapiens]
          Length = 201

 Score = 55.1 bits (131), Expect = 8e-08
 Identities = 35/106 (33%), Positives = 47/106 (44%), Gaps = 3/106 (2%)

Query: 188 EPAFIQKRNERERQRVKCVNEGYARLRGHLPGALAEKRLSKVETLRAAIRYIKYLQELL- 246
           EP      N RER R   VN  +  LR  +P   A+++LSK+ETLR A  YI +L  +L 
Sbjct: 73  EPRQRHTANARERDRTNSVNTAFTALRTLIPTEPADRKLSKIETLRLASSYISHLGNVLL 132

Query: 247 --SSAPDGSTPPASRGLPGTGPCPAPPATPRPDRPGDGEARAPSSL 290
              +  DG    +           +PP  P P    DGE   P  +
Sbjct: 133 AGEACGDGQPCHSGPAFFHAARAGSPPPPPPPPPARDGENTQPKQI 178


>gi|186972126 scleraxis homolog A [Homo sapiens]
          Length = 201

 Score = 55.1 bits (131), Expect = 8e-08
 Identities = 35/106 (33%), Positives = 47/106 (44%), Gaps = 3/106 (2%)

Query: 188 EPAFIQKRNERERQRVKCVNEGYARLRGHLPGALAEKRLSKVETLRAAIRYIKYLQELL- 246
           EP      N RER R   VN  +  LR  +P   A+++LSK+ETLR A  YI +L  +L 
Sbjct: 73  EPRQRHTANARERDRTNSVNTAFTALRTLIPTEPADRKLSKIETLRLASSYISHLGNVLL 132

Query: 247 --SSAPDGSTPPASRGLPGTGPCPAPPATPRPDRPGDGEARAPSSL 290
              +  DG    +           +PP  P P    DGE   P  +
Sbjct: 133 AGEACGDGQPCHSGPAFFHAARAGSPPPPPPPPPARDGENTQPKQI 178


>gi|12545384 basic helix-loop-helix transcription factor HAND2 [Homo
           sapiens]
          Length = 217

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 32/84 (38%), Positives = 47/84 (55%), Gaps = 10/84 (11%)

Query: 167 YAGVFPYVPFPGAFGVYEYPFEPAFIQKR---NERERQRVKCVNEGYARLRGHLPGALAE 223
           Y GV P    PG  G       P  +++R   N +ER+R + +N  +A LR  +P   A+
Sbjct: 80  YGGVPPGAGPPGLGG-------PRPVKRRGTANRKERRRTQSINSAFAELRECIPNVPAD 132

Query: 224 KRLSKVETLRAAIRYIKYLQELLS 247
            +LSK++TLR A  YI YL +LL+
Sbjct: 133 TKLSKIKTLRLATSYIAYLMDLLA 156


>gi|23097242 nephew of atonal 3 [Homo sapiens]
          Length = 166

 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 28/56 (50%), Positives = 38/56 (67%)

Query: 193 QKRNERERQRVKCVNEGYARLRGHLPGALAEKRLSKVETLRAAIRYIKYLQELLSS 248
           Q  N RER+R+  +NE + +LR  +P    EKRLS++ETLR AI YI ++ ELL S
Sbjct: 104 QAANIRERKRMFNLNEAFDQLRRKVPTFAYEKRLSRIETLRLAIVYISFMTELLES 159


>gi|29126247 basic helix-loop-helix family, member a15 [Homo
           sapiens]
          Length = 189

 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 33/78 (42%), Positives = 43/78 (55%), Gaps = 7/78 (8%)

Query: 192 IQKR---NERERQRVKCVNEGYARLRGHLPGALAEKRLSKVETLRAAIRYIKYLQELLSS 248
           IQ+R   NERERQR+  +N  +  LR  +P   A+K+LSK+ETL  A  YIK L   + +
Sbjct: 74  IQRRLESNERERQRMHKLNNAFQALREVIPHVRADKKLSKIETLTLAKNYIKSLTATILT 133

Query: 249 APDGSTPPASRGLPGTGP 266
                 P    GL G GP
Sbjct: 134 MSSSRLP----GLEGPGP 147


>gi|38455396 neurogenin 1 [Homo sapiens]
          Length = 237

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 43/119 (36%), Positives = 54/119 (45%), Gaps = 12/119 (10%)

Query: 194 KRNERERQRVKCVNEGYARLRGHLPGALAEKRLSKVETLRAAIRYIKYLQELLSSAPDGS 253
           K N+RER R+  +N     LR  LP    + +L+K+ETLR A  YI  L E L  A  G 
Sbjct: 96  KANDRERNRMHNLNAALDALRSVLPSFPDDTKLTKIETLRFAYNYIWALAETLRLADQGL 155

Query: 254 TPPASRGL---PGTGPCPAPPATPRPDRP--GDGEARA-----PSSLVPESSESSCFSP 302
               +R     P   PC   P +P  D    G G A A     PSS  P +SE   + P
Sbjct: 156 PGGGARERLLPPQCVPCLPGPPSPASDAESWGSGAAAASPLSDPSS--PAASEDFTYRP 212


>gi|4758506 basic helix-loop-helix transcription factor HAND1 [Homo
           sapiens]
          Length = 215

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 42/144 (29%), Positives = 63/144 (43%), Gaps = 29/144 (20%)

Query: 143 PAEPLGNVPFLLYPGPA---EPPYYDAY----AGVFPYVPFPG----------AFGVYEY 185
           PA P+ + PFL  P      E PY+ ++    A   P  P  G          A+G    
Sbjct: 18  PAHPMLHEPFLFGPASRCHQERPYFQSWLLSPADAAPDFPAGGPPPAAAAAATAYGPDAR 77

Query: 186 PFE-PAFIQKRNER-----------ERQRVKCVNEGYARLRGHLPGALAEKRLSKVETLR 233
           P + P  ++    R           ER+R + +N  +A LR  +P   A+ +LSK++TLR
Sbjct: 78  PGQSPGRLEALGGRLGRRKGSGPKKERRRTESINSAFAELRECIPNVPADTKLSKIKTLR 137

Query: 234 AAIRYIKYLQELLSSAPDGSTPPA 257
            A  YI YL ++L+       P A
Sbjct: 138 LATSYIAYLMDVLAKDAQSGDPEA 161


>gi|23111009 myogenic differentiation 1 [Homo sapiens]
          Length = 320

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 35/92 (38%), Positives = 44/92 (47%), Gaps = 4/92 (4%)

Query: 198 RERQRVKCVNEGYARLRGHLPGALAEKRLSKVETLRAAIRYIKYLQELLSSAPDGSTPPA 257
           RER+R+  VNE +  L+     +   +RL KVE LR AIRYI+ LQ LL    D    P 
Sbjct: 117 RERRRLSKVNEAFETLK-RCTSSNPNQRLPKVEILRNAIRYIEGLQALLR---DQDAAPP 172

Query: 258 SRGLPGTGPCPAPPATPRPDRPGDGEARAPSS 289
                   P P PP        GD +A +P S
Sbjct: 173 GAAAAFYAPGPLPPGRGGEHYSGDSDASSPRS 204


>gi|17981708 twist homolog 2 [Homo sapiens]
          Length = 160

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 31/80 (38%), Positives = 45/80 (56%), Gaps = 7/80 (8%)

Query: 175 PFPGAFGVYEYPFEPAFIQKR------NERERQRVKCVNEGYARLRGHLPGALAEKRLSK 228
           P PG  G    P   +F + +      N RERQR + +NE +A LR  +P  L   +LSK
Sbjct: 45  PTPGKRGKKGSPSAQSFEELQSQRILANVRERQRTQSLNEAFAALRKIIP-TLPSDKLSK 103

Query: 229 VETLRAAIRYIKYLQELLSS 248
           ++TL+ A RYI +L ++L S
Sbjct: 104 IQTLKLAARYIDFLYQVLQS 123


>gi|4885619 T-cell acute lymphocytic leukemia 2 [Homo sapiens]
          Length = 108

 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 28/65 (43%), Positives = 40/65 (61%)

Query: 196 NERERQRVKCVNEGYARLRGHLPGALAEKRLSKVETLRAAIRYIKYLQELLSSAPDGSTP 255
           N RER R + VN  +A+LR  +P    +K+LSK ETLR A+RYI +L ++L       T 
Sbjct: 8   NTRERWRQQNVNSAFAKLRKLIPTHPPDKKLSKNETLRLAMRYINFLVKVLGEQSLQQTG 67

Query: 256 PASRG 260
            A++G
Sbjct: 68  VAAQG 72


>gi|4885075 atonal homolog 1 [Homo sapiens]
          Length = 354

 Score = 49.3 bits (116), Expect = 4e-06
 Identities = 26/61 (42%), Positives = 36/61 (59%)

Query: 196 NERERQRVKCVNEGYARLRGHLPGALAEKRLSKVETLRAAIRYIKYLQELLSSAPDGSTP 255
           N RER+R+  +N  + +LR  +P    +K+LSK ETL+ A  YI  L ELL +   G  P
Sbjct: 165 NARERRRMHGLNHAFDQLRNVIPSFNNDKKLSKYETLQMAQIYINALSELLQTPSGGEQP 224

Query: 256 P 256
           P
Sbjct: 225 P 225


>gi|4507363 T-cell acute lymphocytic leukemia 1 [Homo sapiens]
          Length = 331

 Score = 49.3 bits (116), Expect = 4e-06
 Identities = 39/119 (32%), Positives = 54/119 (45%), Gaps = 9/119 (7%)

Query: 196 NERERQRVKCVNEGYARLRGHLPGALAEKRLSKVETLRAAIRYIKYLQELLSSAPDGSTP 255
           N RER R + VN  +A LR  +P    +K+LSK E LR A++YI +L +LL+   +  T 
Sbjct: 193 NSRERWRQQNVNGAFAELRKLIPTHPPDKKLSKNEILRLAMKYINFLAKLLNDQEEEGTQ 252

Query: 256 PASRGLPGTGPCPAPPATPRPDRPGDGEARAPSSLVPE--SSESSCFSPSPFLESEESW 312
            A  G         P         G G    P  L+ +  S  SSC S      S +S+
Sbjct: 253 RAKTG-------KDPVVGAGGGGGGGGGGAPPDDLLQDVLSPNSSCGSSLDGAASPDSY 304


>gi|4507741 twist [Homo sapiens]
          Length = 202

 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 25/53 (47%), Positives = 36/53 (67%), Gaps = 1/53 (1%)

Query: 196 NERERQRVKCVNEGYARLRGHLPGALAEKRLSKVETLRAAIRYIKYLQELLSS 248
           N RERQR + +NE +A LR  +P  L   +LSK++TL+ A RYI +L ++L S
Sbjct: 114 NVRERQRTQSLNEAFAALRKIIP-TLPSDKLSKIQTLKLAARYIDFLYQVLQS 165


>gi|116517330 factor in the germline alpha [Homo sapiens]
          Length = 219

 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 23/56 (41%), Positives = 36/56 (64%)

Query: 196 NERERQRVKCVNEGYARLRGHLPGALAEKRLSKVETLRAAIRYIKYLQELLSSAPD 251
           N +ER+R+K +N G+ARL+  +P     ++ SKV+ L+ A  YI+ L +LL  A D
Sbjct: 71  NAKERERIKNLNRGFARLKALVPFLPQSRKPSKVDILKGATEYIQVLSDLLEGAKD 126


>gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]
          Length = 1690

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 49/175 (28%), Positives = 60/175 (34%), Gaps = 41/175 (23%)

Query: 22   PEAAEGAAGQAGSPGDSAVPPGGSRATDQDKRCRRNKPREKCSRGLPPLSWRTPNSSHQF 81
            P    G  G+ G PG   + P G R        ++  P    S G P  +  T  +    
Sbjct: 1202 PVGIPGLKGERGDPGSPGISPPGPRG-------KKGPPGPPGSSGPPGPAGATGRAPKDI 1254

Query: 82   GDPGQPGDPEGREDQGPGAGVAPRGTMNNNFCRALVDRRPLGPPSCMQLGVMPPPRQAPL 141
             DPG PG      DQGP     PRG              P G P  + L +   P    L
Sbjct: 1255 PDPGPPG------DQGPPGPDGPRGAPG-----------PPGLPGSVDL-LRGEPGDCGL 1296

Query: 142  P-PAEPLGNVPFLLYPGPAEPPYYDAYAGVFPY------VPFPGAFGVYEYPFEP 189
            P P  P         PGP  PP Y  + G          V FPG  G + +P  P
Sbjct: 1297 PGPPGP---------PGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHGFPGPP 1342



 Score = 37.7 bits (86), Expect = 0.013
 Identities = 60/209 (28%), Positives = 72/209 (34%), Gaps = 55/209 (26%)

Query: 22  PEAAEGAAGQAGSPGDSAVPPG--GSRATDQDKRCRRNKPREKCSRGLP-----PLSWRT 74
           P  AEG  G  G  G S  PPG  G++      R + +K  E+   G P     P S   
Sbjct: 531 PPGAEGPPGLPGKHGASG-PPGNKGAKGDMVVSRVKGHKG-ERGPDGPPGFPGQPGSHGR 588

Query: 75  PNSSHQFGDPGQPGDPEGREDQGPG--AGVAPRGTMNNNFCRALVDRRPLGPPSCMQLGV 132
              + + GDPG PGD E     G G    + P G              P+GPP    LG 
Sbjct: 589 DGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAG-----------PVGPPG---LGF 634

Query: 133 MPPP--RQAPLPPAEPLGNVP-------------FLLYPGPAEPPYYDAYAGV--FP--- 172
             PP  R  P  P  P    P              + YPG   PP +D   G   FP   
Sbjct: 635 PGPPGERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQ 694

Query: 173 ----------YVPFPGAFGVYEYPFEPAF 191
                     +   PG  G  E P  P F
Sbjct: 695 GAPGLSGSDGHKGRPGTPGTAEIPGPPGF 723



 Score = 33.5 bits (75), Expect = 0.25
 Identities = 43/146 (29%), Positives = 48/146 (32%), Gaps = 35/146 (23%)

Query: 22  PEAAEGAAGQAGSPGDSAVPPGGSRATDQDKRCRRNKPREKCSRGLPPLSWRTPNSSHQF 81
           P+  EG AG  G PG    PPG S                 C RG P +         Q 
Sbjct: 808 PKGREGHAGFPGVPG----PPGHS-----------------CERGAPGIPG-------QP 839

Query: 82  GDPGQPGDPEGREDQGPGAGVAPRGTMNNNFCRALVDRRPL-GPPSCMQLGVMPPPRQAP 140
           G PG PG P     +G    V P G         L  R    GPP     G+  P     
Sbjct: 840 GLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLP--GIPGPFGDDG 897

Query: 141 LP----PAEPLGNVPFLLYPGPAEPP 162
           LP    P  P G   F  +PG    P
Sbjct: 898 LPGPPGPKGPRGLPGFPGFPGERGKP 923



 Score = 33.1 bits (74), Expect = 0.33
 Identities = 46/176 (26%), Positives = 58/176 (32%), Gaps = 40/176 (22%)

Query: 19   KARPEAAEGAAGQAGSPGDSAVPPGGSRATDQDKRCRRNKPREKCSRGLPPLSWRTPNSS 78
            K  P +  G  G  G PG    P G   A+ +        PR    R  PP S   P   
Sbjct: 1074 KGDPASHFGPPGPKGEPGSPGCP-GHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCP 1132

Query: 79   HQFGDPGQPGDPEGREDQGP-----GAGV-------APRGTMNNNFCRALVDRR------ 120
               G PG  G P    D GP       G+        P G+   N    L  ++      
Sbjct: 1133 GDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGAS 1192

Query: 121  ---PLGPPSCMQL-------------GVMPP-PRQAPLPPAEPLGNVPFLLYPGPA 159
                +GPP  + +             G+ PP PR    PP  P  + P    PGPA
Sbjct: 1193 GLHDVGPPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSGP----PGPA 1244



 Score = 33.1 bits (74), Expect = 0.33
 Identities = 42/153 (27%), Positives = 53/153 (34%), Gaps = 32/153 (20%)

Query: 22   PEAAEGAAGQAGSPGDSAVPPGGSRAT--------DQDKRCRRNKPREKCSRGLP----- 68
            P    G  G  G PG S  PPG + AT        D      +  P     RG P     
Sbjct: 1222 PPGPRGKKGPPGPPGSSG-PPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGL 1280

Query: 69   ----PLSWRTPNSSHQFGDPGQPGDP-----------EGREDQ-GPGAGVAPRGTMNNNF 112
                 L    P      G PG PG P           +G++ Q GP     P+G   + F
Sbjct: 1281 PGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGP--HGF 1338

Query: 113  CRALVDRRPLGPPSCMQLGVMPPPRQAPLPPAE 145
                 ++   GPP       +P PR  P PPA+
Sbjct: 1339 PGPPGEKGLPGPPGRKGPTGLPGPRGEPGPPAD 1371



 Score = 32.7 bits (73), Expect = 0.43
 Identities = 30/105 (28%), Positives = 38/105 (36%), Gaps = 29/105 (27%)

Query: 21  RPEAAEGAAGQAGSPGDSAVPPGGSRATDQDKRCRRNKPREKCSRGLPPLSWRTPNSSHQ 80
           RP++A G  G+ GSPG    P                        GL  L    P SS  
Sbjct: 427 RPDSAPGKPGKPGSPGLPGAP------------------------GLQGL----PGSSVI 458

Query: 81  FGDPGQPGDPEGREDQGPGAGVAPRGTMNNNFCRALVDRRPLGPP 125
           +   G PG    +   GP  G  P+G   N    A  +  P+GPP
Sbjct: 459 YCSVGNPGPQGIKGKVGPPGGRGPKGEKGNEGLCA-CEPGPMGPP 502



 Score = 32.7 bits (73), Expect = 0.43
 Identities = 69/292 (23%), Positives = 88/292 (30%), Gaps = 85/292 (29%)

Query: 27   GAAGQAGSPGDSAVPPGGSRATDQDKRCRRNKPREKCSRGLPPLSWRTPNSSHQFGDPGQ 86
            G  G+ GSPG    PPG S   D  +  + NK       G P   +  P    + G PG 
Sbjct: 1048 GDQGEPGSPG----PPGFS-GIDGARGPKGNK-------GDPASHFGPPGPKGEPGSPGC 1095

Query: 87   PGDPEGREDQGPGAGVAPRGTMNNNFCRALVDRRP-----LGPPSCMQLGVMPPPRQAPL 141
            PG      +QG      PRG+            RP      GPP C     MP  R  P 
Sbjct: 1096 PGHFGASGEQGLPGIQGPRGSPG----------RPGPPGSSGPPGCPGDHGMPGLRGQPG 1145

Query: 142  PPAEP----LGNVPFLLYP----GPAEPPYYDAYAGVFPYVPFPGAFGVYEY-PFEPAFI 192
               +P    L   P +  P    GP+  P  +   G+       GA G+++  P  P  I
Sbjct: 1146 EMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGI 1205

Query: 193  QKRNERERQRVKCVNEGYARLRGHLPGALAEKRLSKVETLRAAIRYIKYLQELLSSAPDG 252
                                     PG   E+                           G
Sbjct: 1206 -------------------------PGLKGERG---------------------DPGSPG 1219

Query: 253  STPPASRGLPGTGPCPAPPATPRPDRPGDGEARAPSSLVPESSESSCFSPSP 304
             +PP  RG  G    P PP +  P  P     RAP  +           P P
Sbjct: 1220 ISPPGPRGKKGP---PGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGP 1268



 Score = 31.2 bits (69), Expect = 1.2
 Identities = 52/192 (27%), Positives = 63/192 (32%), Gaps = 48/192 (25%)

Query: 22  PEAAEGAAGQAGSPGDSAV----PPG--------GSRATDQDKRCRRNKPREKCSRGLPP 69
           P  + G  GQ G PGD A     PPG        G +    D  C    P  +   G+P 
Sbjct: 746 PPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPGC----PGAEGPAGIPG 801

Query: 70  -LSWRTPNSSH-QFGDPGQPGDPEGREDQG-------------PGAGVAPRGTMNNNFCR 114
            L  + P       G PG PG P    ++G             PG+  AP G        
Sbjct: 802 FLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPG--- 858

Query: 115 ALVDRRPLGPPSCMQLGVMPPPRQAPLPPA-----EPLGNVPFLLYPGPAEPPYYDAYAG 169
              D  P GP     L  +P    A  PP       P G+      PGP  P     + G
Sbjct: 859 ---DVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPG 915

Query: 170 VFPYVPFPGAFG 181
                 FPG  G
Sbjct: 916 ------FPGERG 921



 Score = 30.4 bits (67), Expect = 2.1
 Identities = 27/85 (31%), Positives = 33/85 (38%), Gaps = 8/85 (9%)

Query: 27  GAAGQAGSPGDSAVPPGGSRATDQDKRCRRNKPREKCSRGLP-----PLSWRTPNSSHQF 81
           G +G+ G  GD   PPG   A D+  +     P      G+P     P     P  S   
Sbjct: 86  GLSGEKGMRGDRG-PPGA--AGDKGDKGPTGVPGFPGLDGIPGHPGPPGPRGKPGMSGHN 142

Query: 82  GDPGQPGDPEGREDQGPGAGVAPRG 106
           G  G PG P GR   GPG  +   G
Sbjct: 143 GSRGDPGFPGGRGALGPGGPLGHPG 167



 Score = 30.4 bits (67), Expect = 2.1
 Identities = 47/174 (27%), Positives = 61/174 (35%), Gaps = 15/174 (8%)

Query: 22   PEAAEGAAGQAGSPGDSAVP--PG--GSRATDQDKRC--RRNKPREKCSRGLPPLSWRTP 75
            P   +G  G  G  G   +P  PG  G R     + C   + +P EK   GLP       
Sbjct: 892  PFGDDGLPGPPGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPG-DRGLR 950

Query: 76   NSSHQFGDPGQPGDPEGREDQGPGAGVAPRGTMNNNFCRALVDRRPLGPPSCMQLGVMPP 135
             +    G PG  G+      +G      P G  ++ F     D+   G P  MQ     P
Sbjct: 951  GAKGAIGPPGDEGEMAIISQKGTPGEPGPPG--DDGFPGERGDK---GTPG-MQGRRGEP 1004

Query: 136  PRQAPLPPAEPLGNVPFLLYPGPAEPPYYDAYAGVFPYVPFPGAFGVYEYPFEP 189
             R  P  P    G       PGP  PP      G+  ++ FPG  G    P  P
Sbjct: 1005 GRYGP--PGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSP 1056



 Score = 28.9 bits (63), Expect = 6.2
 Identities = 52/214 (24%), Positives = 71/214 (33%), Gaps = 59/214 (27%)

Query: 22  PEAAEGAAGQAGSPGDSAVP-------PGGSRATDQDKRCRRNK----------PREKCS 64
           P    G +G  GS GD   P       PGG      +K  + N             ++  
Sbjct: 132 PRGKPGMSGHNGSRGDPGFPGGRGALGPGGPLGHPGEKGEKGNSVFILGAVKGIQGDRGD 191

Query: 65  RGLP--PLSWRT---------PNSSHQFGDPGQPGDPEGREDQGPGAGVAPRGTMNN--- 110
            GLP  P SW           P      G PGQPG P  + +  PG GV  +G M +   
Sbjct: 192 PGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRPGLKGN--PGVGV--KGQMGDPGE 247

Query: 111 ----------------NFCRALVDRRPLGPPSCMQLGVMPPPRQAPLPPAEPLGNVPFLL 154
                           +FC    ++   G P    +G+  PP +         G      
Sbjct: 248 VGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPG--MVGLPGPPGRKGESGIGAKGEKGIPG 305

Query: 155 YPGP-AEP-----PYYDAYAGVFPYVPFPGAFGV 182
           +PGP  +P     P +    G    V  PG FG+
Sbjct: 306 FPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGL 339


>gi|119508426 alpha 3 type IX collagen [Homo sapiens]
          Length = 684

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 46/163 (28%), Positives = 58/163 (35%), Gaps = 20/163 (12%)

Query: 22  PEAAEGAAGQAGSPGDSAVP--PGGSRATDQD-KRCRRNKPREKCSRGLPPLSWRTPNSS 78
           P   +GA G+ G PG++ +P  PG    T +D     +  P E+ S G        P   
Sbjct: 60  PPGPKGAPGKPGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLG--------PPGP 111

Query: 79  HQFGDPGQPGDPEGREDQGPGAGVAPRGTMNNNFCRALVDRRPLGPPSCMQLGVMPPPRQ 138
              G  G PG P      GP  G+  RG    +    L    P GPP        PP   
Sbjct: 112 PGLGGKGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPG--PPGPPG-------PPGHP 162

Query: 139 APLPPAEPLGNVPFLLYPGPAEPPYYDAYAGVFPYVPFPGAFG 181
             LP        P +  PGP  PP    + G   Y    G  G
Sbjct: 163 GVLPEGATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVG 205



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 65/258 (25%), Positives = 87/258 (33%), Gaps = 51/258 (19%)

Query: 27  GAAGQAGSPGDSAVPPGGSRATDQDKRCRRNKPREKCSRGLP--PLSWRTPNSSHQFGDP 84
           G  G+AG  G+  VP       ++ +   R        +G P  P            GDP
Sbjct: 355 GELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDP 414

Query: 85  GQPGDPEGRE----DQGPGAGVAPRGTMNNNFCRALV-DRRPLGPPSCMQLGVMPPPRQA 139
           G PG P+G      D+GPG    P+G         L  D+  LGP      G++ P  ++
Sbjct: 415 GLPG-PQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPS-----GLVGPKGES 468

Query: 140 -------PLPPAEPLGNVPFLLYPGPAEPPYYDAYAGVFPYVPFPGAFGVYEYPFEPAFI 192
                  P     P G       PGP  P       GV      PG  G      +P   
Sbjct: 469 GSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGV------PGITG------KPGVP 516

Query: 193 QKRNERERQRVKC---VNEGYARLRGHLPGALAEKRLSKVETLRAAIRYIKYLQELLSSA 249
            K    +R R  C   ++E  A+L  HL   LA   + +                  +  
Sbjct: 517 GKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGP---------------AGP 561

Query: 250 PDGSTPPASRGLPGT-GP 266
           P    PP S G PG  GP
Sbjct: 562 PGPPGPPGSIGHPGARGP 579



 Score = 30.4 bits (67), Expect = 2.1
 Identities = 49/173 (28%), Positives = 62/173 (35%), Gaps = 43/173 (24%)

Query: 20  ARPEAAEGAAGQAGSPGDSA-VPPGGSRATDQDKRCRRNKPREKCSRG-LPPLSWRTPNS 77
           A P+  +G AG  G PGD   + P G                E  SRG L P   + PN 
Sbjct: 435 AGPKGDQGIAGSDGLPGDKGELGPSG----------LVGPKGESGSRGELGPKGTQGPNG 484

Query: 78  SHQFGDPGQPGDPEGREDQG-PGA-------GVAPRGTMN---NNFCRALVD-------- 118
           +   G  G PG P     QG PG        GV  +          C  ++         
Sbjct: 485 TS--GVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAA 542

Query: 119 --RRPLGPPSCMQLGVMPPPRQAPLPPAEPLGNVPFLLYPGPAEPPYYDAYAG 169
             R+PL P S  +    P P   P PP  P G++    +PG   PP Y    G
Sbjct: 543 HLRKPLAPGSIGR----PGPAGPPGPPGPP-GSIG---HPGARGPPGYRGPTG 587



 Score = 30.0 bits (66), Expect = 2.8
 Identities = 36/129 (27%), Positives = 48/129 (37%), Gaps = 22/129 (17%)

Query: 26  EGAAGQAGSPGDSAVPPGGSRATDQDKRCRRNKPREKCSRG-LPPLSWRTPNSSHQFGDP 84
           +G  G  G PG + +P  GS    Q  R  R  P      G   P+ +R P      G P
Sbjct: 207 DGEKGDPGPPGPAGLP--GSVGL-QGPRGLRGLPGPLGPPGDRGPIGFRGPP-----GIP 258

Query: 85  GQPGDPEGREDQGPGAGVAPRGTMNNNFCRALVDRRPLGPPSCMQLGVMPPPRQAPLPPA 144
           G PG    R ++GP     P+G +            P G P     GV  P  +  +P  
Sbjct: 259 GAPGKAGDRGERGPEGFRGPKGDLGR--------PGPKGTP-----GVAGPSGEPGMPGK 305

Query: 145 EPLGNVPFL 153
           +    VP L
Sbjct: 306 DGQNGVPGL 314



 Score = 28.9 bits (63), Expect = 6.2
 Identities = 37/125 (29%), Positives = 47/125 (37%), Gaps = 32/125 (25%)

Query: 28  AAGQAGSPGDSAVPPGGSRATDQDKRCRRNKPREKCSRGLP----PLSWRTPNSSHQFGD 83
           A G  G PG +  PPG               P    S G P    P  +R P    + GD
Sbjct: 549 APGSIGRPGPAG-PPG--------------PPGPPGSIGHPGARGPPGYRGPTG--ELGD 591

Query: 84  PGQPGDPEGREDQG-PGAGV-APRGTMNNNFCRALVDRRPLGPPSCMQLGVMPPPRQAPL 141
           PG  G+   R D+G  GAG+  P G            + P G P   + G    P + P 
Sbjct: 592 PGPRGNQGDRGDKGAAGAGLDGPEGDQG--------PQGPQGVPGTSKDGQDGAPGE-PG 642

Query: 142 PPAEP 146
           PP +P
Sbjct: 643 PPGDP 647


>gi|48255909 basic helix-loop-helix transcription factor 15 [Homo
           sapiens]
          Length = 199

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 27/63 (42%), Positives = 36/63 (57%), Gaps = 3/63 (4%)

Query: 193 QKRNERERQRVKCVNEGYARLRGHLPGALAEKRLSKVETLRAAIRYIKYLQELL---SSA 249
           Q  N RER R + VN  +  LR  +P    +++LSK+ETLR A  YI +L  +L    SA
Sbjct: 75  QAANARERDRTQSVNTAFTALRTLIPTEPVDRKLSKIETLRLASSYIAHLANVLLLGDSA 134

Query: 250 PDG 252
            DG
Sbjct: 135 DDG 137


>gi|6382071 diaphanous 2 isoform 12C [Homo sapiens]
          Length = 1096

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 23/54 (42%), Positives = 33/54 (61%)

Query: 223 EKRLSKVETLRAAIRYIKYLQELLSSAPDGSTPPASRGLPGTGPCPAPPATPRP 276
           +KR  K++ L A I+ ++   ++LSS+     PPA+  LPG GP P PPA P P
Sbjct: 519 QKRDEKIKELEAEIQQLRTQAQVLSSSSGIPGPPAAPPLPGVGPPPPPPAPPLP 572



 Score = 28.9 bits (63), Expect = 6.2
 Identities = 37/148 (25%), Positives = 52/148 (35%), Gaps = 31/148 (20%)

Query: 19  KARPEAAEGAAGQAGSPGDSAVPPGGSRATDQDKRCRRNKPREKCSRGLPPLSWRTPNSS 78
           KA+ E +E  A +     D       +R   Q +  +R++  ++    +  L  +    S
Sbjct: 487 KAKVEESEQKAAEFSKKFDEEFT---ARQEAQAELQKRDEKIKELEAEIQQLRTQAQVLS 543

Query: 79  HQFGDPGQPGDPEGREDQGPGAGVAPRGTMNNNFCRALVDRRPLGPPSCMQLGVMPPPRQ 138
              G PG P  P       PG G  P                P  PP      + PPP  
Sbjct: 544 SSSGIPGPPAAPPL-----PGVGPPPP---------------PPAPPLPGGAPLPPPPPP 583

Query: 139 AP----LPPAEPLGNVPFLLYPGPAEPP 162
            P    +PP  P    P LL+ GP  PP
Sbjct: 584 LPGMMGIPPPPP----PPLLFGGPPPPP 607


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.136    0.434 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,079,257
Number of Sequences: 37866
Number of extensions: 1351180
Number of successful extensions: 12718
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 187
Number of HSP's successfully gapped in prelim test: 623
Number of HSP's that attempted gapping in prelim test: 8111
Number of HSP's gapped (non-prelim): 4288
length of query: 313
length of database: 18,247,518
effective HSP length: 102
effective length of query: 211
effective length of database: 14,385,186
effective search space: 3035274246
effective search space used: 3035274246
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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