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Search of human proteins with 239747195
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239747195 PREDICTED: similar to PITSLRE protein kinase beta
SV2 [Homo sapiens]
(153 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239747195 PREDICTED: similar to PITSLRE protein kinase beta S... 317 2e-87
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 312 8e-86
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 299 7e-82
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 298 1e-81
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 298 1e-81
gi|169161522 PREDICTED: similar to cell division cycle 2-like 1 ... 295 8e-81
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 289 6e-79
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 222 1e-58
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 218 2e-57
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 67 8e-12
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 64 7e-11
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 62 2e-10
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 60 6e-10
gi|148746195 trichohyalin [Homo sapiens] 55 3e-08
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 54 4e-08
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 54 7e-08
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 53 9e-08
gi|62244004 modulator of estrogen induced transcription isoform ... 52 2e-07
gi|63176611 modulator of estrogen induced transcription isoform ... 52 2e-07
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 52 2e-07
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 52 3e-07
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 52 3e-07
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 52 3e-07
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 52 3e-07
gi|239747174 PREDICTED: hypothetical protein XP_002343931, parti... 52 3e-07
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 51 4e-07
gi|56549694 enabled homolog isoform a [Homo sapiens] 51 4e-07
gi|39930375 enabled homolog isoform b [Homo sapiens] 51 4e-07
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 50 6e-07
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 50 6e-07
>gi|239747195 PREDICTED: similar to PITSLRE protein kinase beta SV2
[Homo sapiens]
Length = 153
Score = 317 bits (813), Expect = 2e-87
Identities = 153/153 (100%), Positives = 153/153 (100%)
Query: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI
Sbjct: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
Query: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHE 120
TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHE
Sbjct: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHE 120
Query: 121 RRKRHREEQDKARREWERQKRREMAREHSRRER 153
RRKRHREEQDKARREWERQKRREMAREHSRRER
Sbjct: 121 RRKRHREEQDKARREWERQKRREMAREHSRRER 153
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 312 bits (799), Expect = 8e-86
Identities = 152/153 (99%), Positives = 152/153 (99%)
Query: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI
Sbjct: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
Query: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHE 120
TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMS KEKVHHRKDEKRKEKWKHARVKEREHE
Sbjct: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKWKHARVKEREHE 120
Query: 121 RRKRHREEQDKARREWERQKRREMAREHSRRER 153
RRKRHREEQDKARREWERQKRREMAREHSRRER
Sbjct: 121 RRKRHREEQDKARREWERQKRREMAREHSRRER 153
Score = 41.2 bits (95), Expect = 3e-04
Identities = 37/154 (24%), Positives = 68/154 (44%), Gaps = 18/154 (11%)
Query: 2 GDEKDSWKVKTLDEILQEKK-------RRKEQEEKAEIK------RLKNSDDRDSKRDSL 48
G+E DS +K ++ +++K +RKE+ + A +K R ++ +++D R
Sbjct: 77 GEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKARREW 136
Query: 49 EEGELRDHCMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEK 108
E + R+ E + R R + +E + E + + + +Q KE+ R +E+RKE+
Sbjct: 137 ERQKRREMAREHSRRERD--RLEQLERKRERERKMREQQKEQREQKER-ERRAEERRKER 193
Query: 109 WKHARVKEREHERRKRHREEQDKARREWERQKRR 142
AR + H R R W R R
Sbjct: 194 --EARREVSAHHRTMREDYSDKVKASHWSRSPPR 225
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 299 bits (765), Expect = 7e-82
Identities = 151/163 (92%), Positives = 151/163 (92%), Gaps = 10/163 (6%)
Query: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI
Sbjct: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
Query: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEK----------WK 110
TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMS KEKVHHRKDEKRKEK K
Sbjct: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKCRHHSHSAEGGK 120
Query: 111 HARVKEREHERRKRHREEQDKARREWERQKRREMAREHSRRER 153
HARVKEREHERRKRHREEQDKARREWERQKRREMAREHSRRER
Sbjct: 121 HARVKEREHERRKRHREEQDKARREWERQKRREMAREHSRRER 163
Score = 36.2 bits (82), Expect = 0.011
Identities = 33/140 (23%), Positives = 59/140 (42%), Gaps = 6/140 (4%)
Query: 3 DEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITI 62
DEK K + + K + +E + E +R ++ +++D R E + R+ E +
Sbjct: 102 DEKRKEKCRHHSHSAEGGKHARVKEREHE-RRKRHREEQDKARREWERQKRREMAREHSR 160
Query: 63 RNSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERR 122
R R + +E + E + + + +Q KE+ R +E+RKE+ AR + H R
Sbjct: 161 RERD--RLEQLERKRERERKMREQQKEQREQKER-ERRAEERRKER--EARREVSAHHRT 215
Query: 123 KRHREEQDKARREWERQKRR 142
R W R R
Sbjct: 216 MREDYSDKVKASHWSRSPPR 235
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 298 bits (763), Expect = 1e-81
Identities = 151/155 (97%), Positives = 151/155 (97%), Gaps = 3/155 (1%)
Query: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI
Sbjct: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
Query: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARV--KERE 118
TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMS KEKVHHRKDEKRKEK KHARV KERE
Sbjct: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEK-KHARVKEKERE 119
Query: 119 HERRKRHREEQDKARREWERQKRREMAREHSRRER 153
HERRKRHREEQDKARREWERQKRREMAREHSRRER
Sbjct: 120 HERRKRHREEQDKARREWERQKRREMAREHSRRER 154
Score = 40.4 bits (93), Expect = 6e-04
Identities = 34/130 (26%), Positives = 59/130 (45%), Gaps = 6/130 (4%)
Query: 14 DEILQEKKRRKEQEEKAEIKRLK-NSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDS 72
DE +EKK + +E++ E +R K + +++D R E + R+ E + R R +
Sbjct: 102 DEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERD--RLEQ 159
Query: 73 MEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKA 132
+E + E + + + +Q KE+ R +E+RKE+ AR + H R R
Sbjct: 160 LERKRERERKMREQQKEQREQKER-ERRAEERRKER--EARREVSAHHRTMREDYSDKVK 216
Query: 133 RREWERQKRR 142
W R R
Sbjct: 217 ASHWSRSPPR 226
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
8 [Homo sapiens]
Length = 780
Score = 298 bits (763), Expect = 1e-81
Identities = 151/155 (97%), Positives = 151/155 (97%), Gaps = 3/155 (1%)
Query: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI
Sbjct: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
Query: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARV--KERE 118
TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMS KEKVHHRKDEKRKEK KHARV KERE
Sbjct: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEK-KHARVKEKERE 119
Query: 119 HERRKRHREEQDKARREWERQKRREMAREHSRRER 153
HERRKRHREEQDKARREWERQKRREMAREHSRRER
Sbjct: 120 HERRKRHREEQDKARREWERQKRREMAREHSRRER 154
Score = 37.0 bits (84), Expect = 0.007
Identities = 35/137 (25%), Positives = 61/137 (44%), Gaps = 11/137 (8%)
Query: 14 DEILQEKKRRKEQEEKAEIKRLK-NSDDRDSKRDSLEEGELRDHCMEITIRNSP------ 66
DE +EKK + +E++ E +R K + +++D R E + R+ E + R
Sbjct: 102 DEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERGNDGVCL 161
Query: 67 YR-REDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRH 125
+R R + +E + E + + + +Q KE+ R +E+RKE+ AR + H R R
Sbjct: 162 FRDRLEQLERKRERERKMREQQKEQREQKER-ERRAEERRKER--EARREVSAHHRTMRE 218
Query: 126 REEQDKARREWERQKRR 142
W R R
Sbjct: 219 DYSDKVKASHWSRSPPR 235
>gi|169161522 PREDICTED: similar to cell division cycle 2-like 1
(PITSLRE proteins) [Homo sapiens]
Length = 155
Score = 295 bits (756), Expect = 8e-81
Identities = 149/155 (96%), Positives = 149/155 (96%), Gaps = 2/155 (1%)
Query: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDH MEI
Sbjct: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEI 60
Query: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARV--KERE 118
TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMS KEK HHRKDEKRKEK KHARV KERE
Sbjct: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKERE 120
Query: 119 HERRKRHREEQDKARREWERQKRREMAREHSRRER 153
HERRKRHREEQDKARREWERQKRREMAREHSRRER
Sbjct: 121 HERRKRHREEQDKARREWERQKRREMAREHSRRER 155
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 289 bits (740), Expect = 6e-79
Identities = 150/165 (90%), Positives = 150/165 (90%), Gaps = 12/165 (7%)
Query: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDH MEI
Sbjct: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEI 60
Query: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEK----------WK 110
TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMS KEKVHHRKDEKRKEK K
Sbjct: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKRRHRSHSAEGGK 120
Query: 111 HARV--KEREHERRKRHREEQDKARREWERQKRREMAREHSRRER 153
HARV KEREHERRKRHREEQDKARREWERQKRREMAREHSRRER
Sbjct: 121 HARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRER 165
Score = 37.7 bits (86), Expect = 0.004
Identities = 29/123 (23%), Positives = 54/123 (43%), Gaps = 5/123 (4%)
Query: 20 KKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGEE 79
K R +++E+ +R ++ +++D R E + R+ E + R R + +E + E
Sbjct: 120 KHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERD--RLEQLERKRER 177
Query: 80 DDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKARREWERQ 139
+ + + +Q KE+ R +E+RKE+ AR + H R R W R
Sbjct: 178 ERKMREQQKEQREQKER-ERRAEERRKER--EARREVSAHHRTMREDYSDKVKASHWSRS 234
Query: 140 KRR 142
R
Sbjct: 235 PPR 237
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 222 bits (565), Expect = 1e-58
Identities = 113/121 (93%), Positives = 114/121 (94%), Gaps = 3/121 (2%)
Query: 35 LKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSWK 94
+ SDDRDSKRDSLEEGELRDH MEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMS K
Sbjct: 1 MSQSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRK 60
Query: 95 EKVHHRKDEKRKEKWKHARV--KEREHERRKRHREEQDKARREWERQKRREMAREHSRRE 152
EKVHHRKDEKRKEK KHARV KEREHERRKRHREEQDKARREWERQKRREMAREHSRRE
Sbjct: 61 EKVHHRKDEKRKEK-KHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRE 119
Query: 153 R 153
R
Sbjct: 120 R 120
Score = 40.4 bits (93), Expect = 6e-04
Identities = 34/130 (26%), Positives = 59/130 (45%), Gaps = 6/130 (4%)
Query: 14 DEILQEKKRRKEQEEKAEIKRLK-NSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDS 72
DE +EKK + +E++ E +R K + +++D R E + R+ E + R R +
Sbjct: 68 DEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERD--RLEQ 125
Query: 73 MEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKA 132
+E + E + + + +Q KE+ R +E+RKE+ AR + H R R
Sbjct: 126 LERKRERERKMREQQKEQREQKER-ERRAEERRKER--EARREVSAHHRTMREDYSDKVK 182
Query: 133 RREWERQKRR 142
W R R
Sbjct: 183 ASHWSRSPPR 192
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 218 bits (554), Expect = 2e-57
Identities = 113/131 (86%), Positives = 114/131 (87%), Gaps = 12/131 (9%)
Query: 35 LKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSWK 94
+ SDDRDSKRDSLEEGELRDH MEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMS K
Sbjct: 1 MSQSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRK 60
Query: 95 EKVHHRKDEKRKEK----------WKHARV--KEREHERRKRHREEQDKARREWERQKRR 142
EKVHHRKDEKRKEK KHARV KEREHERRKRHREEQDKARREWERQKRR
Sbjct: 61 EKVHHRKDEKRKEKRRHRSHSAEGGKHARVKEKEREHERRKRHREEQDKARREWERQKRR 120
Query: 143 EMAREHSRRER 153
EMAREHSRRER
Sbjct: 121 EMAREHSRRER 131
Score = 56.6 bits (135), Expect = 8e-09
Identities = 40/153 (26%), Positives = 73/153 (47%), Gaps = 14/153 (9%)
Query: 2 GDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEIT 61
G+E DS +K ++ +++K ++EK + KR S + + + + + R+H
Sbjct: 43 GEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKRRHRSHSAEGGKHARVKEKEREH----- 97
Query: 62 IRNSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKERE-HE 120
E R E+D + Q+ + H R++ R E+ + R +ER+ E
Sbjct: 98 --------ERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMRE 149
Query: 121 RRKRHREEQDKARREWERQKRREMAREHSRRER 153
++K RE++++ RR ER+K RE RE S R
Sbjct: 150 QQKEQREQKERERRAEERRKEREARREVSAHHR 182
Score = 37.7 bits (86), Expect = 0.004
Identities = 29/123 (23%), Positives = 54/123 (43%), Gaps = 5/123 (4%)
Query: 20 KKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGEE 79
K R +++E+ +R ++ +++D R E + R+ E + R R + +E + E
Sbjct: 86 KHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERD--RLEQLERKRER 143
Query: 80 DDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKARREWERQ 139
+ + + +Q KE+ R +E+RKE+ AR + H R R W R
Sbjct: 144 ERKMREQQKEQREQKER-ERRAEERRKER--EARREVSAHHRTMREDYSDKVKASHWSRS 200
Query: 140 KRR 142
R
Sbjct: 201 PPR 203
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 66.6 bits (161), Expect = 8e-12
Identities = 54/176 (30%), Positives = 88/176 (50%), Gaps = 29/176 (16%)
Query: 3 DEKDSWKVKTLDEILQEKK---RRKEQEEKAEIKRLKNSDDRDS-KRDSLEEGELRDHCM 58
D+ S+K+KT+ + EKK R+K EEKA++++LK ++ ++ K+D ++ E +
Sbjct: 218 DDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFE 277
Query: 59 EITIRNS--------PYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWK 110
E T+++ P E + EDD+ K + K+K K+EK KEK K
Sbjct: 278 EETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKD---KKKKKGEKEEKEKEKKK 334
Query: 111 H-------------ARVKEREHERRKRHREEQDKARREWERQKRREMAREHSRRER 153
A++KE E ER+KR EE+ K E E +++ E E +RER
Sbjct: 335 GPSKATVKAMQEALAKLKEEE-ERQKREEEERIKRLEELEAKRKEEERLEQEKRER 389
Score = 40.0 bits (92), Expect = 8e-04
Identities = 28/125 (22%), Positives = 60/125 (48%), Gaps = 13/125 (10%)
Query: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
M ++++ KV+ ++ K+ +E+EE+ E + +D +S+ + EEGE
Sbjct: 509 MASDEETEKVEGNKVHIEVKENPEEEEEEEE----EEEEDEESEEEEEEEGESEG----- 559
Query: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHE 120
+ ++ + D + +L KP ++MS + + D++ KE+ + + K R +
Sbjct: 560 ---SEGDEEDEKVSDEKDSGKTLDKKPSKEMS-SDSEYDSDDDRTKEERAYDKAKRRIEK 615
Query: 121 RRKRH 125
RR H
Sbjct: 616 RRLEH 620
Score = 35.0 bits (79), Expect = 0.025
Identities = 32/124 (25%), Positives = 62/124 (50%), Gaps = 7/124 (5%)
Query: 20 KKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGEE 79
KK +E++ K++K +S +S +E + + +N + ++E E+
Sbjct: 159 KKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNED 218
Query: 80 DD-SLAIKPPQQMSW--KEKVHHRKDEKRKEKWKHARVKEREH-ERRKRHREEQDKARRE 135
DD S IK Q KE+ ++DE EK K ++KE+E E K+ + +Q +++R+
Sbjct: 219 DDASFKIKTVAQKKAEKKERERKKRDE---EKAKLRKLKEKEELETGKKDQSKQKESQRK 275
Query: 136 WERQ 139
+E +
Sbjct: 276 FEEE 279
Score = 34.7 bits (78), Expect = 0.033
Identities = 39/167 (23%), Positives = 70/167 (41%), Gaps = 34/167 (20%)
Query: 15 EILQEKKRRKEQEEKAEIKRLKNSDDRDS-----------------KRDSLEEGELRDHC 57
E L++K + ++ K +++ SDD D K D EE E D+
Sbjct: 114 EELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDE--DNS 171
Query: 58 MEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKV-----HHRKDEKRKEKWKHA 112
+I R+ R S E E D+ L + Q+ + K K +D+ K K
Sbjct: 172 KKIKERS---RINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTV 228
Query: 113 RVKEREHERRKRHREEQDKA-------RREWERQKRREMAREHSRRE 152
K+ E + R+R + +++KA + E E K+ + ++ S+R+
Sbjct: 229 AQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRK 275
Score = 34.7 bits (78), Expect = 0.033
Identities = 30/127 (23%), Positives = 51/127 (40%), Gaps = 15/127 (11%)
Query: 17 LQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDR 76
+ E K+RK+ ++ E K + S + + + +E+G E P ED+ ED
Sbjct: 445 IYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKE--ETPPPVEPEEEEDT-EDA 501
Query: 77 GEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKARREW 136
G +D W+ + EK + H VKE E + EE++ E
Sbjct: 502 GLDD------------WEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEE 549
Query: 137 ERQKRRE 143
E ++ E
Sbjct: 550 EEEEEGE 556
Score = 32.3 bits (72), Expect = 0.16
Identities = 30/145 (20%), Positives = 60/145 (41%), Gaps = 26/145 (17%)
Query: 6 DSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNS 65
D W+ DE + K + K I+ +N ++ + + + EE E
Sbjct: 504 DDWEAMASDE-----ETEKVEGNKVHIEVKENPEEEEEEEEEEEEDE------------- 545
Query: 66 PYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRH 125
E+ E+ GE + S + +++S ++ D+K ++ + + +R K
Sbjct: 546 --ESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEE 603
Query: 126 REEQDKARREWERQKRREMAREHSR 150
R DKA+R E+++ EHS+
Sbjct: 604 R-AYDKAKRRIEKRR-----LEHSK 622
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 63.5 bits (153), Expect = 7e-11
Identities = 45/139 (32%), Positives = 76/139 (54%), Gaps = 4/139 (2%)
Query: 18 QEKKRRKEQEEK-AEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDR 76
+ KKRR+E+E K E K + ++ + + +EG+ R+ E R RE E+R
Sbjct: 96 ERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERER-KEERKREERKERERKKEER 154
Query: 77 GEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARV-KEREHERRKRHREEQDKAR-R 134
+E + K ++ EK RK+++RKE+ K R KER+ ER ++ R E+ K R +
Sbjct: 155 EKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKK 214
Query: 135 EWERQKRREMAREHSRRER 153
+ ER+K R+ R+ + RE+
Sbjct: 215 KEERKKERQKDRQTNWREK 233
Score = 56.6 bits (135), Expect = 8e-09
Identities = 45/149 (30%), Positives = 78/149 (52%), Gaps = 20/149 (13%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRG 77
+E +R+KE+ E+ + KR + + + + ++GE + R RR + G
Sbjct: 55 RESERKKERREREKRKREREKERKRERGKKEKKGERKKE-----ERERKKRRREKENKEG 109
Query: 78 EEDDSLAIKPPQQMSW-------KEKVHHRKDEKRK--EKWKHARVKEREH-ERRKRHRE 127
EE + K ++ +E+ RK E+RK E+ K R KERE ER+KR R+
Sbjct: 110 EEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERK 169
Query: 128 ---EQDKARREWERQKRREMAREHSRRER 153
E+++ R+E ER++R++ RE +R+ER
Sbjct: 170 QVGEKEEERKEKERKERKK--RERNRKER 196
Score = 53.1 bits (126), Expect = 9e-08
Identities = 51/169 (30%), Positives = 80/169 (47%), Gaps = 34/169 (20%)
Query: 18 QEKKRRKE-----------QEEKAEIKRLKNSDDRD----SKRDSLE---------EGEL 53
+EK+R++E +EE+ KR + ++++ KR E EG+
Sbjct: 73 REKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKE 132
Query: 54 RDHCMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKH-- 111
R+ E R RE E+R +E + K ++ EK RK+++RKE+ K
Sbjct: 133 RER-KEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRER 191
Query: 112 ---ARVKEREH-ERRKRHREEQDKARREWERQKRRE---MAREHSRRER 153
R KERE ERR+R +E + K R+ ERQK R+ +E +RER
Sbjct: 192 NRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRER 240
Score = 53.1 bits (126), Expect = 9e-08
Identities = 38/150 (25%), Positives = 74/150 (49%), Gaps = 18/150 (12%)
Query: 2 GDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEIT 61
G+EK+ K K E + K KE+E K E KR + + K + +E E ++
Sbjct: 109 GEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKE------ 162
Query: 62 IRNSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHER 121
R++ + GE+++ K ++ K++ +RK+ K++ + K R +++E ++
Sbjct: 163 ------RKKRERKQVGEKEEER--KEKERKERKKRERNRKERKKERERKERRERKKERKK 214
Query: 122 RKRHREEQDKAR----REWERQKRREMARE 147
++ ++E+ K R RE ER KR R+
Sbjct: 215 KEERKKERQKDRQTNWREKERGKRERKERK 244
Score = 50.4 bits (119), Expect = 6e-07
Identities = 35/135 (25%), Positives = 71/135 (52%), Gaps = 6/135 (4%)
Query: 20 KKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGEE 79
++R +E E + E K+ + S+ + +R E E R E + ++E E + EE
Sbjct: 39 REREREIETRKEGKKERESERKKERR----EREKRKREREKERKRERGKKEKKGERKKEE 94
Query: 80 DDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARV-KEREHERRKRHREEQDKARREWER 138
+ + ++ E+ RK +++KE+ + ++ KERE + ++ E +++ R++ ER
Sbjct: 95 RERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEER 154
Query: 139 QKRREMAREHSRRER 153
+K RE +E +RER
Sbjct: 155 EKERE-RKERKKRER 168
Score = 48.5 bits (114), Expect = 2e-06
Identities = 34/116 (29%), Positives = 60/116 (51%), Gaps = 9/116 (7%)
Query: 18 QEKKR--RKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMED 75
+E+KR RKE+E K E + + KR+ + GE + E R +RE + ++
Sbjct: 137 EERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKE-KERKERKKRERNRKE 195
Query: 76 RGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDK 131
R +E + ++ ++K +K+E++KE+ K + RE ER KR R+E+ K
Sbjct: 196 RKKE------RERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
Score = 43.5 bits (101), Expect = 7e-05
Identities = 31/110 (28%), Positives = 55/110 (50%), Gaps = 15/110 (13%)
Query: 50 EGELRDHCMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKW 109
+ E+R+ EI R + +S + + ++ +E+ RK E+ K++
Sbjct: 35 QSEIREREREIETRKEGKKERESERKKERRE--------REKRKREREKERKRERGKKEK 86
Query: 110 KHARVKEREHERRKRHREEQDKARREWERQKRRE------MAREHSRRER 153
K R KE E ER+KR RE+++K E E++K++E ++E RER
Sbjct: 87 KGERKKE-ERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERER 135
Score = 42.4 bits (98), Expect = 2e-04
Identities = 36/141 (25%), Positives = 63/141 (44%), Gaps = 25/141 (17%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRG 77
+E + RKE +++ E +R K +R+ ++ E+ R+ E +G
Sbjct: 43 REIETRKEGKKERESERKKERREREKRKREREKERKRER--------------GKKEKKG 88
Query: 78 EEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKER-----EHERRKRHREEQDKA 132
E K ++ + + K+ + KEK K KER E + R+R E + +
Sbjct: 89 ERK-----KEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREE 143
Query: 133 RREWERQKRREMAREHSRRER 153
R+E ER K+ E +E R+ER
Sbjct: 144 RKERER-KKEEREKERERKER 163
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 62.0 bits (149), Expect = 2e-10
Identities = 38/135 (28%), Positives = 72/135 (53%), Gaps = 8/135 (5%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRG 77
+ +K+RKE+ EK KR K R+ K+ E + + E R + RRE + R
Sbjct: 81 EREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKE-RERENKQRRERKRKKRR 139
Query: 78 EEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKARREWE 137
+ K ++ +EK +++ KRK++ K R K+RE R++R +E + K RRE +
Sbjct: 140 K-------KKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERK 192
Query: 138 RQKRREMAREHSRRE 152
+++++E ++ R++
Sbjct: 193 KERKKERRKKKERKK 207
Score = 60.5 bits (145), Expect = 6e-10
Identities = 40/136 (29%), Positives = 70/136 (51%), Gaps = 13/136 (9%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRG 77
+EKK+RK++E E +R + +R+ +R E E R + +RE R
Sbjct: 61 KEKKKRKKRERGKERERKRK--EREKQRKERREKERRKR------KKEKKKRERKQRGRR 112
Query: 78 EEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKARREWE 137
E K ++ + + R++ KRK++ K R KER+ E+ + RE + K R++ E
Sbjct: 113 ERK-----KKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEE 167
Query: 138 RQKRREMAREHSRRER 153
R+K+RE R+ ++ER
Sbjct: 168 REKKRERNRKERKKER 183
Score = 59.7 bits (143), Expect = 9e-10
Identities = 40/141 (28%), Positives = 72/141 (51%), Gaps = 7/141 (4%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRG 77
+EK+R++E+ +K + KR K ++ +R E + R E R ++E +R
Sbjct: 50 REKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKR--KKEKKKRERK 107
Query: 78 EEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKARREWE 137
+ K ++ + + R++ KRK++ K R KER+ E+ + RE + K R++ E
Sbjct: 108 QRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEE 167
Query: 138 RQKRREMAR-----EHSRRER 153
R+K+RE R E R+ER
Sbjct: 168 REKKRERNRKERKKERERKER 188
Score = 55.8 bits (133), Expect = 1e-08
Identities = 40/141 (28%), Positives = 73/141 (51%), Gaps = 7/141 (4%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRG 77
+E+++RK + EK E KR + ++ KR E G+ R+ + + RRE R
Sbjct: 41 REREKRKREREK-ERKRERGKKEK-KKRKKRERGKERERKRKEREKQRKERREKERRKRK 98
Query: 78 EEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHE-RRKRHREEQDKARREW 136
+E K + K+K ++ E+ ++ + + K+R + RRK + E+++ +RE
Sbjct: 99 KEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRER 158
Query: 137 ERQKR----REMAREHSRRER 153
+R+KR RE RE +R+ER
Sbjct: 159 KRKKRKKEEREKKRERNRKER 179
Score = 47.8 bits (112), Expect = 4e-06
Identities = 28/83 (33%), Positives = 44/83 (53%), Gaps = 15/83 (18%)
Query: 86 KPPQQMSWKEKVHHRKDEKRKEKWKHARVKER---------------EHERRKRHREEQD 130
KP Q + K R+ EKRK + + R +ER E ER+++ RE+Q
Sbjct: 27 KPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQR 86
Query: 131 KARREWERQKRREMAREHSRRER 153
K RRE ER+KR++ ++ R++R
Sbjct: 87 KERREKERRKRKKEKKKRERKQR 109
Score = 46.2 bits (108), Expect = 1e-05
Identities = 32/137 (23%), Positives = 67/137 (48%), Gaps = 29/137 (21%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRG 77
+E +R+KE+ E+ + KR + +++ KR+ R +++ +RG
Sbjct: 32 RESERKKERREREKRKRER---EKERKRE----------------RGKKEKKKRKKRERG 72
Query: 78 EEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKE-REHERRKRHREEQDKARREW 136
+E ++ KE+ RK+ + KE+ K + K+ RE ++R R ++ K R+E
Sbjct: 73 KE---------RERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKER 123
Query: 137 ERQKRREMAREHSRRER 153
ER+ ++ R+ +R +
Sbjct: 124 ERENKQRRERKRKKRRK 140
Score = 43.9 bits (102), Expect = 5e-05
Identities = 23/97 (23%), Positives = 45/97 (46%)
Query: 57 CMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKE 116
C + RRE R E + + ++ ++K K+ +RK K + + KE
Sbjct: 29 CTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKE 88
Query: 117 REHERRKRHREEQDKARREWERQKRREMAREHSRRER 153
R + R++ ++E+ K R+ ++ R+ +E RER
Sbjct: 89 RREKERRKRKKEKKKRERKQRGRRERKKKKERKERER 125
Score = 41.6 bits (96), Expect = 3e-04
Identities = 28/130 (21%), Positives = 75/130 (57%), Gaps = 7/130 (5%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRG 77
+++K+++E++++ +R K + ++ +R++ + E + R +RE ++RG
Sbjct: 98 KKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKRE---KERG 154
Query: 78 EEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKAR-REW 136
+ + + ++ K++ +RK E++KE+ + R +ER+ ER+K R+++++ + R+
Sbjct: 155 KRERKRKKRKKEERE-KKRERNRK-ERKKERERKER-RERKKERKKERRKKKERKKDRKT 211
Query: 137 ERQKRREMAR 146
+RQ ++ R
Sbjct: 212 DRQTDSQVFR 221
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 60.5 bits (145), Expect = 6e-10
Identities = 43/142 (30%), Positives = 79/142 (55%), Gaps = 9/142 (6%)
Query: 14 DEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSM 73
DE+ ++++R + + ++ + +R + + +RD +R+ E E R+ E R+ +E +
Sbjct: 652 DELERDERREERRVDRVDDRRDERARERDRERERDRERE-RERERE---RDREREKEREL 707
Query: 74 E-DRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKA 132
E +R E + K + +++ H R+ E+ +E+ R KERE ER +R RE + +
Sbjct: 708 ERERAREREREREKERDRERDRDRDHDRERERERER---DREKEREREREERERERERER 764
Query: 133 RREWERQKRREMAREHSR-RER 153
RE ER++ RE ARE + RER
Sbjct: 765 ERERERERERERARERDKERER 786
Score = 55.1 bits (131), Expect = 2e-08
Identities = 41/151 (27%), Positives = 67/151 (44%), Gaps = 20/151 (13%)
Query: 14 DEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSM 73
DE +E+ R +E++ + E +R + D K LE R+ E R D
Sbjct: 673 DERARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRERDRDRD 732
Query: 74 EDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKAR 133
DR E + + +EK R+ E+R+ + + R +ERE ER + E+DK R
Sbjct: 733 HDRERERE--------RERDREKEREREREERERERERERERERERERERERARERDKER 784
Query: 134 ---REWE---------RQKRREMAREHSRRE 152
R+WE R+KR E+ + + R+
Sbjct: 785 ERQRDWEDKDKGRDDRREKREEIREDRNPRD 815
Score = 48.5 bits (114), Expect = 2e-06
Identities = 37/157 (23%), Positives = 70/157 (44%), Gaps = 10/157 (6%)
Query: 3 DEKDSWKVKTLDEILQEKKRR----KEQEEKAEIKRLKNSDD--RDSKRDSLEEGELRDH 56
D +D + + + E+ RR ++Q + I+ +D+ RD +R+ + D
Sbjct: 612 DNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDR 671
Query: 57 CMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKE 116
E R D +R E + + ++ +E+ R+ E+ KE+ + R ++
Sbjct: 672 RDERARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRE-RDRD 730
Query: 117 REHERRKRHREEQDKARREWERQKRREMAREHSRRER 153
R+H+R + E+D RE ER++ RE RER
Sbjct: 731 RDHDRERERERERD---REKEREREREERERERERER 764
Score = 48.5 bits (114), Expect = 2e-06
Identities = 39/149 (26%), Positives = 67/149 (44%), Gaps = 23/149 (15%)
Query: 5 KDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRN 64
+D K K+L EI E+K R +Q ++ E R +SD +DS R+
Sbjct: 1233 RDREKTKSL-EITGERKSRIDQLKRGEPSRSTSSDRQDS-------------------RS 1272
Query: 65 SPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHER--- 121
RR DR S + ++ +++ H ++ +R+ + R +R+ ++
Sbjct: 1273 HSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWP 1332
Query: 122 RKRHREEQDKARREWERQKRREMAREHSR 150
R R R+ + RE ER KRR++ RE R
Sbjct: 1333 RNRDRDRLRERERERERDKRRDLDRERER 1361
Score = 40.8 bits (94), Expect = 5e-04
Identities = 33/141 (23%), Positives = 61/141 (43%), Gaps = 5/141 (3%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITI---RNSPYRREDSME 74
+E+ R +E+E + E +R + + K E RDH E R+ RE E
Sbjct: 695 RERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKERERERE 754
Query: 75 DRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRH--REEQDKA 132
+R E + + ++ +E+ R E+ +++ + K R+ R KR RE+++
Sbjct: 755 ERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPR 814
Query: 133 RREWERQKRREMAREHSRRER 153
ER+ ++ E S R
Sbjct: 815 DGHDERKSKKRYRNEGSPSPR 835
Score = 40.0 bits (92), Expect = 8e-04
Identities = 36/137 (26%), Positives = 56/137 (40%), Gaps = 4/137 (2%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRRE-DSMEDR 76
Q RR E+ E KR + D R+ + ++ RDH + R+ RR+ DR
Sbjct: 408 QSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDR 467
Query: 77 GEEDDSLAIKPPQQM-SWKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKARRE 135
E DS ++ ++M + +D + + A R+ E R HR+E D E
Sbjct: 468 RELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAH-DYRDREGRDTHRKE-DTYPEE 525
Query: 136 WERQKRREMAREHSRRE 152
R + E SR E
Sbjct: 526 SRSYGRNHLREESSRTE 542
Score = 37.0 bits (84), Expect = 0.007
Identities = 42/169 (24%), Positives = 71/169 (42%), Gaps = 31/169 (18%)
Query: 4 EKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSD-DRDSKRDSLEEGELRDHCMEITI 62
EK+ + + E +E++R +E+E + E +R + D +R+ +RD ++ + RD E
Sbjct: 746 EKEREREREERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRRE--- 802
Query: 63 RNSPYRREDSMEDRGEEDDSLAIK----------PPQQMSWKEKVHHRKD-------EKR 105
+RE+ EDR D K P + S K + H D + +
Sbjct: 803 -----KREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDK 857
Query: 106 KEKWKHARVKEREHERRK---RHREEQDKARREWERQKRREMAREHSRR 151
EK + R E R H E + R W+ + R+ +E SRR
Sbjct: 858 NEKHRLLSQVVRPQESRSLSPSHLTEDRQGR--WKEEDRKPERKESSRR 904
Score = 33.5 bits (75), Expect = 0.073
Identities = 27/137 (19%), Positives = 55/137 (40%), Gaps = 15/137 (10%)
Query: 24 KEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGEEDDSL 83
+E+ + EI+ ++ R R+ G R E+ + S RG + DS
Sbjct: 535 REESSRTEIRNESRNESRSEIRND-RMGRSRGRVPELP-------EKGSRGSRGSQIDSH 586
Query: 84 AIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKARREW------- 136
+ SW+ + + + ++ E+ + ++ ERR R+ +D R+
Sbjct: 587 SSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIR 646
Query: 137 ERQKRREMAREHSRRER 153
+ + E+ R+ R ER
Sbjct: 647 HQGRNDELERDERREER 663
Score = 32.3 bits (72), Expect = 0.16
Identities = 21/68 (30%), Positives = 31/68 (45%), Gaps = 3/68 (4%)
Query: 87 PPQQMS-WKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKARREWERQKRREMA 145
PP+ S +EK H D +R + R + RE R KR RE+ + RE+E+ +
Sbjct: 388 PPRHRSPMREKGRH--DHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRD 445
Query: 146 REHSRRER 153
R R
Sbjct: 446 HRDDREPR 453
Score = 28.1 bits (61), Expect = 3.1
Identities = 19/95 (20%), Positives = 41/95 (43%), Gaps = 6/95 (6%)
Query: 63 RNSPYRREDSMEDRGEED-----DSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKER 117
+ SP R M ++G D S + ++ + K KD + + +++ + R
Sbjct: 385 KQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSR 444
Query: 118 EHERRKRHREEQDKARREWERQKRREMAREHSRRE 152
+H + R+ +D+ R + + RRE+ R+
Sbjct: 445 DHRDDREPRDGRDR-RDARDTRDRRELRDSRDMRD 478
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 54.7 bits (130), Expect = 3e-08
Identities = 40/161 (24%), Positives = 89/161 (55%), Gaps = 18/161 (11%)
Query: 3 DEKDSWK-----VKTLDEILQEK---KRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELR 54
+E+ W+ ++ +E LQE+ ++R+ QEE+ ++++L+ + R +++ ++ +
Sbjct: 241 EEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRL 300
Query: 55 DHCMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARV 114
++ + RRE E R +++ + QQ +E+ R+ E+R+E+
Sbjct: 301 RREQQLRRKQEEERREQQEERREQQE-----RREQQEERREQQLRREQEERREQQLR--- 352
Query: 115 KEREHERRKRH-REEQDKARREWERQKRREMAREHS-RRER 153
+E+E ERR++ R EQ++ RRE + ++ +++ RE RRE+
Sbjct: 353 REQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQ 393
Score = 53.1 bits (126), Expect = 9e-08
Identities = 38/157 (24%), Positives = 79/157 (50%), Gaps = 7/157 (4%)
Query: 3 DEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLE-EGELRDHCM--- 58
+E+ +++ E +E++ R+EQEE+ ++L+ + + + L E +LR
Sbjct: 332 EERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRR 391
Query: 59 -EITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKER 117
+ R RRE + + ++ QQ+ +E+ R ++K +++ + R+K
Sbjct: 392 EQQLRREQQLRREQQLRREQQLRREQQLRREQQLR-REQEEERHEQKHEQERREQRLKRE 450
Query: 118 EHERRKRHREEQDKARREWERQKRR-EMAREHSRRER 153
+ ERR + E++ R E ER+K++ + +E RRER
Sbjct: 451 QEERRDWLKREEETERHEQERRKQQLKRDQEEERRER 487
Score = 52.4 bits (124), Expect = 2e-07
Identities = 36/163 (22%), Positives = 76/163 (46%), Gaps = 17/163 (10%)
Query: 3 DEKDSWKVKTLDEILQEKKR----------RKEQE--EKAEIKRLKNSDDRDSKRDSLEE 50
+EK + + D + QE++ RKE+E ++ E +R + + + + LE
Sbjct: 224 EEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLER 283
Query: 51 GELRDHCMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWK 110
ELR E + RRE + + EE+ + QQ +E+ R+ ++ + + +
Sbjct: 284 QELRRERQEEEQQQQRLRREQQLRRKQEEE-----RREQQEERREQQERREQQEERREQQ 338
Query: 111 HARVKEREHERRKRHREEQDKARREWERQKRREMAREHSRRER 153
R +E E++ R +E+++ ++ R++ E + RRE+
Sbjct: 339 LRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQ 381
Score = 51.6 bits (122), Expect = 3e-07
Identities = 32/158 (20%), Positives = 82/158 (51%), Gaps = 8/158 (5%)
Query: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
+G+E+++ + + L+ ++++ +++EE+ + + ++ +R EE EL+ ++
Sbjct: 1064 LGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQL 1123
Query: 61 TIRNSPYRREDSM-------EDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHAR 113
RR + E+ +E++ L + P++ +E ++E+ ++ +
Sbjct: 1124 LREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQL 1183
Query: 114 VKEREHERRKRHREEQDKARREWERQKRREMAREHSRR 151
++E E E+R++ RE Q + E +RQKR++ R+ +R
Sbjct: 1184 LRE-EQEKRRQERERQYREEEELQRQKRKQRYRDEDQR 1220
Score = 50.1 bits (118), Expect = 8e-07
Identities = 30/154 (19%), Positives = 73/154 (47%), Gaps = 4/154 (2%)
Query: 3 DEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITI 62
+ ++ + + E +E++ R+EQEE+ E ++L+ + + + L + + +
Sbjct: 320 ERREQQERREQQEERREQQLRREQEERRE-QQLRREQEEERREQQLRREQEEERREQQLR 378
Query: 63 RNSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERR 122
R RRE + + ++ QQ+ ++++ + +R+++ + + +ER ++
Sbjct: 379 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKH 438
Query: 123 KRHREEQDKARREWERQ---KRREMAREHSRRER 153
++ R EQ R + ER+ KR E H + R
Sbjct: 439 EQERREQRLKREQEERRDWLKREEETERHEQERR 472
Score = 49.7 bits (117), Expect = 1e-06
Identities = 39/143 (27%), Positives = 73/143 (51%), Gaps = 9/143 (6%)
Query: 11 KTLDEILQEKKRRKEQEEKAE--IKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYR 68
K L++ +E++ ++EQEE+ + +KR + + KR+ E E R E+ R
Sbjct: 556 KRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEER 615
Query: 69 REDSMEDRGEEDD---SLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRH 125
RE ++ E++ L Q+ ++++ + E+R+++ K +ER +R KR
Sbjct: 616 REQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKRE 675
Query: 126 REEQDKARREWE-RQKRREMARE 147
EE+ RRE E ++ +E ARE
Sbjct: 676 HEEE---RREQELAEEEQEQARE 695
Score = 49.3 bits (116), Expect = 1e-06
Identities = 36/156 (23%), Positives = 77/156 (49%), Gaps = 18/156 (11%)
Query: 3 DEKDSWKVKTLDEILQEKKRRK-----EQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHC 57
+E+ W + + E++RRK +QEE+ + LK ++ ++ E +LR
Sbjct: 452 EERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLR--- 508
Query: 58 MEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKER 117
R RRE ++ R EE++ L Q++ ++++ ++E+R++ K K
Sbjct: 509 -----REQEERREQRLK-RQEEEERL----QQRLRSEQQLRREQEERREQLLKREEEKRL 558
Query: 118 EHERRKRHREEQDKARREWERQKRREMAREHSRRER 153
E ERR++ + + + RR+ ++ E ++ +RE+
Sbjct: 559 EQERREQRLKREQEERRDQLLKREEERRQQRLKREQ 594
Score = 48.9 bits (115), Expect = 2e-06
Identities = 41/161 (25%), Positives = 78/161 (48%), Gaps = 17/161 (10%)
Query: 4 EKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRD------SLEEGELRDHC 57
E+ ++K E ++ +R+E+ E+ E +R K RD + + LEE E R+
Sbjct: 441 ERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQ 500
Query: 58 --MEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVK 115
E +R R + R EE++ L Q++ ++++ ++E+R++ K K
Sbjct: 501 ERREQQLRREQEERREQRLKRQEEEERLQ----QRLRSEQQLRREQEERREQLLKREEEK 556
Query: 116 EREHERR----KRHREEQ-DKARREWERQKRREMAREHSRR 151
E ERR KR +EE+ D+ + E ++++ + RE R
Sbjct: 557 RLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEER 597
Score = 48.1 bits (113), Expect = 3e-06
Identities = 35/152 (23%), Positives = 79/152 (51%), Gaps = 14/152 (9%)
Query: 14 DEILQEKKRRKEQEEKAEIKRLKNSD----DRDSKRDSL----EEGELRDHCMEITIRNS 65
+E +++ +R+E+EE+ + +RL++ +++ +R+ L EE L E ++
Sbjct: 512 EERREQRLKRQEEEERLQ-QRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKRE 570
Query: 66 PYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEK-RKEKWKHARVKEREHERRKR 124
R D + R EE +K Q+ ++++ + E+ +E+ + R+K E E +R
Sbjct: 571 QEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERR 630
Query: 125 HR----EEQDKARREWERQKRREMAREHSRRE 152
+ EEQ++ R++ R++++E + +RE
Sbjct: 631 QQLLKSEEQEERRQQQLRREQQERREQRLKRE 662
Score = 47.4 bits (111), Expect = 5e-06
Identities = 35/164 (21%), Positives = 78/164 (47%), Gaps = 30/164 (18%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRG 77
+E+ R EQEE+ E +RLK + + +R L + E ++ + +R R + R
Sbjct: 604 REEVERLEQEERRE-QRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKRE 662
Query: 78 EEDDSLAIKPPQQMSWKEKVHHRKDEKRKE----------KWK--------------HAR 113
EE++ L + ++ + + +E++++ KW+ ++R
Sbjct: 663 EEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSR 722
Query: 114 VKEREHERRKRHREEQDKARR---EWERQKR--REMAREHSRRE 152
+++E +RR++ +EE+ + R +W+ ++R R+ E RR+
Sbjct: 723 PRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRD 766
Score = 47.0 bits (110), Expect = 6e-06
Identities = 39/151 (25%), Positives = 68/151 (45%), Gaps = 15/151 (9%)
Query: 14 DEILQEKKRRKEQ-------EEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSP 66
+E Q +++R+E+ EE+ +++R + + + D L+E + R E R
Sbjct: 815 EEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQE--QRRDQ 872
Query: 67 YRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRHR 126
R E+R +L KP Q + K E+ +E + R K R E+ +++R
Sbjct: 873 KWRWQLEEERKRRRHTLYAKPALQEQLR-KEQQLLQEEEEELQREEREKRRRQEQERQYR 931
Query: 127 EEQDKARRE-----WERQKRREMAREHSRRE 152
EE+ + E ER+KRR RE R+
Sbjct: 932 EEEQLQQEEEQLLREEREKRRRQERERQYRK 962
Score = 47.0 bits (110), Expect = 6e-06
Identities = 41/153 (26%), Positives = 75/153 (49%), Gaps = 21/153 (13%)
Query: 15 EILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSP----YRRE 70
+IL+E++ R E+EE+ +++R +RD K EE +LR E +R+ +R E
Sbjct: 1748 KILEEEQLRPEREEQ-QLRR----QERDRK--FREEEQLRQEREEQQLRSQESDRKFREE 1800
Query: 71 DSMEDRGEEDDSLAIKPPQQMSWKEK---VHHRKDEKRKEKWKHARVKEREHERRKRHRE 127
+ + EE + + W+E+ + ++ R+E+ + R +E+ + K RE
Sbjct: 1801 EQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRRE 1860
Query: 128 EQD-------KARREWERQKRREMAREHSRRER 153
EQ+ K R+E ER+ R E R + E+
Sbjct: 1861 EQELWQEEEQKRRQERERKLREEHIRRQQKEEQ 1893
Score = 46.6 bits (109), Expect = 8e-06
Identities = 37/169 (21%), Positives = 84/169 (49%), Gaps = 34/169 (20%)
Query: 3 DEKDSWKVKTLDEILQEKKRRKE--------QEEKAEIKRLKNSDDRDSKRDSLEEGELR 54
D+K W+++ +E+KRR+ QE+ + ++L ++ + +R+ E+ +
Sbjct: 871 DQKWRWQLE------EERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQ 924
Query: 55 DHCMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWK---- 110
+ + YR E+ ++ EE+ L + ++ + + +RKD+K ++K +
Sbjct: 925 E-------QERQYREEEQLQQ--EEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLG 975
Query: 111 HARVKEREHERRKRHREEQD-------KARREWERQKRREMAREHSRRE 152
K R ER K++REE++ R E E+++R+E R++ +++
Sbjct: 976 EEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKD 1024
Score = 46.6 bits (109), Expect = 8e-06
Identities = 41/158 (25%), Positives = 72/158 (45%), Gaps = 22/158 (13%)
Query: 17 LQEKKRRKEQ---EEKAEIKRLKNSDDR--DSKRDSLEEGELRDHCMEITIRNSPYRRED 71
LQE+ R+++Q EE+ E++R + R + +R EE +L+ ++ RR
Sbjct: 895 LQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQ 954
Query: 72 SMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREH----ERRKRHRE 127
E + +D L K Q + + + R++ ++K + + +E E ER KR R+
Sbjct: 955 ERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQ 1014
Query: 128 EQDKARRE-------------WERQKRREMAREHSRRE 152
E ++ R+ ER+KRR RE RE
Sbjct: 1015 EWERQYRKKDELQQEEEQLLREEREKRRLQERERQYRE 1052
Score = 46.2 bits (108), Expect = 1e-05
Identities = 36/139 (25%), Positives = 71/139 (51%), Gaps = 8/139 (5%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCM--EITIRNSPYRREDSMED 75
+++ RR+++EE+ E K+ +R +R E+ E RD E T R+ RR+ ++
Sbjct: 422 EQQLRREQEEERHE---QKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKR 478
Query: 76 RGEEDDSLAIKPPQQMSWKEKVHHRKDEKRK--EKWKHARVKEREHERRKRHR-EEQDKA 132
EE+ ++ +E+ R+ + R+ E+ + R+K +E E R + R + +
Sbjct: 479 DQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQL 538
Query: 133 RREWERQKRREMAREHSRR 151
RRE E ++ + + RE +R
Sbjct: 539 RREQEERREQLLKREEEKR 557
Score = 45.4 bits (106), Expect = 2e-05
Identities = 33/133 (24%), Positives = 67/133 (50%), Gaps = 3/133 (2%)
Query: 14 DEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSL---EEGELRDHCMEITIRNSPYRRE 70
++ L++++ RK +EE+ ++ + +RD EE +LR + R R +
Sbjct: 1452 EQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQ 1511
Query: 71 DSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQD 130
+ EE+ L + Q+ +E+ R+ E+ +++ + K RE E+ ++ REEQ
Sbjct: 1512 EPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQ 1571
Query: 131 KARREWERQKRRE 143
+R+E +R+ R E
Sbjct: 1572 LSRQERDRKFRLE 1584
Score = 44.7 bits (104), Expect = 3e-05
Identities = 40/162 (24%), Positives = 80/162 (49%), Gaps = 25/162 (15%)
Query: 15 EILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCM--EITIRNSPYRREDS 72
++ +E++ R+EQEE E K+ +R +R E+ E RD E T R+ RR+
Sbjct: 418 QLRREQQLRREQEE--ERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQ 475
Query: 73 ME-DRGEEDDSLAIK------PPQQMSWKEKVHHRKDEKRKEKWKHARVKER-------- 117
++ D+ EE +K QQ ++++ ++E+R+++ K +ER
Sbjct: 476 LKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSE 535
Query: 118 ------EHERRKRHREEQDKARREWERQKRREMAREHSRRER 153
+ ERR++ + +++ R E ER+++R + RR++
Sbjct: 536 QQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQ 577
Score = 44.7 bits (104), Expect = 3e-05
Identities = 32/135 (23%), Positives = 71/135 (52%), Gaps = 12/135 (8%)
Query: 20 KKRRKEQEEKAEIKR--LKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRG 77
++RR+EQEEK + L+ ++ + R EE + RD + ++ E+ E RG
Sbjct: 729 QRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQ-------WQAEEKSE-RG 780
Query: 78 EEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKARREWE 137
+ L+ +PP + + ++ + ++R++++ ++ + R++R RE++ + E E
Sbjct: 781 RQ--RLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEE 838
Query: 138 RQKRREMAREHSRRE 152
+ +RRE A++ E
Sbjct: 839 QLQRRERAQQLQEEE 853
Score = 44.7 bits (104), Expect = 3e-05
Identities = 32/161 (19%), Positives = 80/161 (49%), Gaps = 22/161 (13%)
Query: 14 DEILQEKKRRKEQEEKAEIK-RLKNSDDRDSKRDSL------------EEGELRDHCMEI 60
D + ++++RR+ QE++ + K R + ++R +R +L E+ L++ E+
Sbjct: 854 DGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEEL 913
Query: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHE 120
RR E + E++ L + +Q+ +E+ R+ E+ ++ K +++++E +
Sbjct: 914 QREEREKRRRQEQERQYREEEQLQ-QEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQ 972
Query: 121 --------RRKRHREEQDKARREWERQKRREMAREHSRRER 153
RR++ RE++ + E ++++ + + E +R R
Sbjct: 973 LLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRR 1013
Score = 44.7 bits (104), Expect = 3e-05
Identities = 30/151 (19%), Positives = 71/151 (47%), Gaps = 12/151 (7%)
Query: 14 DEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSM 73
DE+ QE+++ +E + + + R+ + EE +L E R R+
Sbjct: 1024 DELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKE 1083
Query: 74 EDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKR--------- 124
E+ +E++ L + P++ +E+ ++E+ ++ + ++E +RR++
Sbjct: 1084 EELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREE 1143
Query: 125 ---HREEQDKARREWERQKRREMAREHSRRE 152
+EE+ R E E+++R+E+ R++ E
Sbjct: 1144 EEVQQEEEQLLREEPEKRRRQELERQYREEE 1174
Score = 44.3 bits (103), Expect = 4e-05
Identities = 33/153 (21%), Positives = 73/153 (47%), Gaps = 4/153 (2%)
Query: 3 DEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITI 62
D+++ + + L +E++ ++E+ E+ + + ++ KR EE + E +
Sbjct: 479 DQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQL 538
Query: 63 RNSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDE--KRKEKWKHARVKEREHE 120
R R + + R EE + Q++ K + R+D+ KR+E+ + R+K + E
Sbjct: 539 RREQEERREQLLKREEEKRLEQERREQRL--KREQEERRDQLLKREEERRQQRLKREQEE 596
Query: 121 RRKRHREEQDKARREWERQKRREMAREHSRRER 153
R ++ + ++ R E E ++ + + RE ER
Sbjct: 597 RLEQRLKREEVERLEQEERREQRLKREEPEEER 629
Score = 44.3 bits (103), Expect = 4e-05
Identities = 28/148 (18%), Positives = 74/148 (50%), Gaps = 8/148 (5%)
Query: 3 DEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITI 62
+E+ +++ + +E++ ++E+EE+ +RLK + + + L E E I
Sbjct: 640 EERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKS 699
Query: 63 RNSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERR 122
R ++ + +E + S P++ +E R++++ K + + + ++ +E ER
Sbjct: 700 RIPKWQWQ--LESEADARQSKVYSRPRK---QEGQRRRQEQEEKRRRRESELQWQEEERA 754
Query: 123 KRHREEQDKARR---EWERQKRREMARE 147
R ++E+++ R +W+ +++ E R+
Sbjct: 755 HRQQQEEEQRRDFTWQWQAEEKSERGRQ 782
Score = 44.3 bits (103), Expect = 4e-05
Identities = 42/148 (28%), Positives = 72/148 (48%), Gaps = 13/148 (8%)
Query: 18 QEKKRR-KEQEEKAEIKRLKNSDDRDSKRDSL------EEGELRDHCMEITIR-NSPYRR 69
QE++R+ +E+EE KR + D D + D +E +RD+ + R N +R+
Sbjct: 1193 QERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQ 1252
Query: 70 -EDS-MEDRGEEDDSLAIKPPQQMSWKEKVHHR---KDEKRKEKWKHARVKEREHERRKR 124
EDS + DR + D + QQ +E+ R +D E+ + R +++E +RR R
Sbjct: 1253 LEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDR 1312
Query: 125 HREEQDKARREWERQKRREMAREHSRRE 152
+E+ + RE +KRR + RE
Sbjct: 1313 KSQEEKQLLREEREEKRRRQETDRKFRE 1340
Score = 43.9 bits (102), Expect = 5e-05
Identities = 29/133 (21%), Positives = 66/133 (49%), Gaps = 10/133 (7%)
Query: 15 EILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSME 74
++ +E++ R+EQ+ + E + + R + + E + E ++ R D ++
Sbjct: 400 QLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLK 459
Query: 75 DRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKARR 134
R EE + +Q K+++ ++E+R+E+W +K E ERR++ + + RR
Sbjct: 460 -REEETER-----HEQERRKQQLKRDQEEERRERW----LKLEEEERREQQERREQQLRR 509
Query: 135 EWERQKRREMARE 147
E E ++ + + R+
Sbjct: 510 EQEERREQRLKRQ 522
Score = 43.1 bits (100), Expect = 9e-05
Identities = 31/135 (22%), Positives = 69/135 (51%), Gaps = 17/135 (12%)
Query: 20 KKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGEE 79
++ R+E+E++ + R + R + + E+ E R R RRE E R ++
Sbjct: 287 RRERQEEEQQQQRLRREQQLRRKQEEERREQQEER--------REQQERREQQEERREQQ 338
Query: 80 DDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKARREWERQ 139
++ Q+ ++++ ++E+R+E+ +E+E ERR++ + + RRE + +
Sbjct: 339 -----LRREQEERREQQLRREQEEERREQQLR---REQEEERREQQLRREQQLRREQQLR 390
Query: 140 KRREMAREHS-RRER 153
+ +++ RE RRE+
Sbjct: 391 REQQLRREQQLRREQ 405
Score = 43.1 bits (100), Expect = 9e-05
Identities = 33/144 (22%), Positives = 74/144 (51%), Gaps = 11/144 (7%)
Query: 14 DEILQEKKRRKEQ-EEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDS 72
+E Q++ RR++Q K E +R + ++R +++ E+ E R + R RRE
Sbjct: 293 EEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERRE--QQLRREQEERREQQ 350
Query: 73 MEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKW--KHARVKEREHERRKRHREEQD 130
+ EE+ + QQ+ +++ R+ + R+E+ + +++ + RR++ +
Sbjct: 351 LRREQEEE-----RREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQ 405
Query: 131 KARREWERQKRREMAREHS-RRER 153
+ RRE + ++ +++ RE RRE+
Sbjct: 406 QLRREQQLRREQQLRREQQLRREQ 429
Score = 43.1 bits (100), Expect = 9e-05
Identities = 33/149 (22%), Positives = 71/149 (47%), Gaps = 15/149 (10%)
Query: 18 QEKKRRKEQEEKAEI------KRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYR--- 68
+++ RR+++E + ++ KRL+ +R +R E+ E RD ++ R
Sbjct: 535 EQQLRREQEERREQLLKREEEKRLE--QERREQRLKREQEERRDQLLKREEERRQQRLKR 592
Query: 69 -REDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHE---RRKR 124
+E+ +E R + ++ ++ ++ + K ++E+R++ K +ER + R ++
Sbjct: 593 EQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQ 652
Query: 125 HREEQDKARREWERQKRREMAREHSRRER 153
R EQ R E E + + + REH R
Sbjct: 653 ERREQRLKREEEEERLEQRLKREHEEERR 681
Score = 43.1 bits (100), Expect = 9e-05
Identities = 34/147 (23%), Positives = 70/147 (47%), Gaps = 13/147 (8%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRD--HCMEITIRNSPYRREDSMED 75
+E++ +E+ EK + + +D K EE L + R YR E+ ++
Sbjct: 939 EEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQ 998
Query: 76 RGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEK---WKHARVKEREHERRKRHREEQDKA 132
E+ + ++ W E+ + +KDE ++E+ + R K R ER +++REE++
Sbjct: 999 EEEQLLREEREKRRRQEW-ERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQ 1057
Query: 133 R-------REWERQKRREMAREHSRRE 152
+ E E ++R+E+ R++ + E
Sbjct: 1058 QEEEQLLGEERETRRRQELERQYRKEE 1084
Score = 43.1 bits (100), Expect = 9e-05
Identities = 37/171 (21%), Positives = 88/171 (51%), Gaps = 19/171 (11%)
Query: 1 MGDEKDSWKVKTLDEILQEKKRRKEQE-----EKAEIKRLKNSDDRDSKRDSLEEGE--- 52
+G+E + + + ++ +E++ +++E E+ E +R + + + K+D L++ E
Sbjct: 974 LGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQL 1033
Query: 53 LRD--HCMEITIRNSPYRREDSMEDR-----GEEDDSLAIKP-PQQMSWKEKVHHRKDEK 104
LR+ + R YR E+ ++ GEE ++ + +Q +E++ +++
Sbjct: 1034 LREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQL 1093
Query: 105 RKEKWKHARVKEREHERRKR---HREEQDKARREWERQKRREMAREHSRRE 152
+E+ + R +ERE + R+ +EE+ R E E+++R+E+ R++ E
Sbjct: 1094 LREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEE 1144
Score = 43.1 bits (100), Expect = 9e-05
Identities = 38/156 (24%), Positives = 75/156 (48%), Gaps = 7/156 (4%)
Query: 3 DEKDSWKVKTLDEILQEKKRRKEQEEK-AEIKRLKNSDDRDSKRDSLEEGELRDHCMEIT 61
D K + + L E +EK+RR+E + K E ++L + R + + R+ +
Sbjct: 1311 DRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQ 1370
Query: 62 IRNSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHH-RKDEKRKEKWKHARVKEREHE 120
+ + E+ R E + +K QQ+ +E+ R+D RK + + ++ +E +
Sbjct: 1371 EQGRKFLEEEQRLRRQERERKF-LKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERD 1429
Query: 121 RRKRHREEQDKARREWER---QKRREMAREHSRRER 153
R+ R EEQ R+E ER ++ +++ +E R+ R
Sbjct: 1430 RKFRE-EEQQVRRQERERKFLEEEQQLRQERHRKFR 1464
Score = 42.7 bits (99), Expect = 1e-04
Identities = 30/145 (20%), Positives = 74/145 (51%), Gaps = 7/145 (4%)
Query: 14 DEILQEKKR---RKEQEEKAE-IKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRR 69
++ L+ K+ R++QEE+ E +R + ++R ++ E+ E R+ ++ RR
Sbjct: 303 EQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERRE--QQLRREQEEERR 360
Query: 70 EDSM-EDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREE 128
E + ++ EE ++ QQ+ ++++ + +R+++ + + RE + R+ +
Sbjct: 361 EQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 420
Query: 129 QDKARREWERQKRREMAREHSRRER 153
+++ R + ++R E E RRE+
Sbjct: 421 REQQLRREQEEERHEQKHEQERREQ 445
Score = 42.4 bits (98), Expect = 2e-04
Identities = 31/151 (20%), Positives = 69/151 (45%), Gaps = 4/151 (2%)
Query: 3 DEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITI 62
++ S K +E E++ R+ E E++R + + +R+ + + E
Sbjct: 191 EQLQSCKGHETEEFPDEEQLRRR--ELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRK 248
Query: 63 RNSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERR 122
R + R+E+ E ++ ++ K + + E+++E+ + R++ + RR
Sbjct: 249 RETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRR 308
Query: 123 KRHREEQDKARREWERQKRREMAREHSRRER 153
K+ E +++ E+Q+RRE E RRE+
Sbjct: 309 KQEEERREQQEERREQQERREQQEE--RREQ 337
Score = 42.4 bits (98), Expect = 2e-04
Identities = 35/153 (22%), Positives = 73/153 (47%), Gaps = 15/153 (9%)
Query: 15 EILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSL--EEGELRDHCMEITIRNSPYRREDS 72
++ +++++RK +E+ +++R + R RD EE +LR E + R+
Sbjct: 1523 QLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFR 1582
Query: 73 MED---RGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQ 129
+E+ R +E + ++ QQ+ +E + E R K++ +E E ++ HR+E+
Sbjct: 1583 LEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQE-RDRKFREDEQLLQEREEQQLHRQER 1641
Query: 130 DKA---------RREWERQKRREMAREHSRRER 153
D+ R+E E+Q R + R+ E+
Sbjct: 1642 DRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQ 1674
Score = 42.0 bits (97), Expect = 2e-04
Identities = 35/131 (26%), Positives = 59/131 (45%), Gaps = 1/131 (0%)
Query: 20 KKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGEE 79
K R EQ + E +L++ + + L E + RD E R R E++ E
Sbjct: 1243 KGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERR-RWQQRDRHFPEEEQLER 1301
Query: 80 DDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKARREWERQ 139
++ K + S +EK R++ + K + + K RE E+ + REEQ R+E +R+
Sbjct: 1302 EEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRK 1361
Query: 140 KRREMAREHSR 150
R E R +
Sbjct: 1362 FREEELRHQEQ 1372
Score = 42.0 bits (97), Expect = 2e-04
Identities = 38/157 (24%), Positives = 73/157 (46%), Gaps = 9/157 (5%)
Query: 3 DEKDSWKVKTLDEILQEKKR--RKEQEEKAEIKRLKNSDDRDSKRDSL----EEGELRDH 56
+ ++ + K D QE+K+ R+E+EEK +R + +D + + + L EE LR
Sbjct: 1300 EREEQKEAKRRDRKSQEEKQLLREEREEK---RRRQETDRKFREEEQLLQEREEQPLRRQ 1356
Query: 57 CMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKE 116
+ R R ++ EE+ L + ++ KE+ R E+ ++ + K
Sbjct: 1357 ERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKF 1416
Query: 117 REHERRKRHREEQDKARREWERQKRREMAREHSRRER 153
RE E++ +E K R E ++ +R+E R+ E+
Sbjct: 1417 REEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQ 1453
Score = 41.2 bits (95), Expect = 3e-04
Identities = 27/154 (17%), Positives = 76/154 (49%), Gaps = 4/154 (2%)
Query: 4 EKDSWKVKTLDEILQEKK-RRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITI 62
E+D + + D L+E+ +R+ Q+ + + + L +++ K++ LE+ + + E+
Sbjct: 116 EEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWR 175
Query: 63 RNSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERR 122
+ ++ + E+ S ++ +E++ R+ + + K + + ++R +
Sbjct: 176 QRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQD 235
Query: 123 KRHREEQDKARREWE---RQKRREMAREHSRRER 153
+ +EE++K R+ E R++ ++ E +R+R
Sbjct: 236 RVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQR 269
Score = 41.2 bits (95), Expect = 3e-04
Identities = 32/133 (24%), Positives = 62/133 (46%), Gaps = 6/133 (4%)
Query: 22 RRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRG-EED 80
RRK +EEK + +R + +D EE E R + + E+ R +E+
Sbjct: 219 RRKGREEKQQQRR----ERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEE 274
Query: 81 DSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKARREWERQK 140
+ K +Q +E+ + ++R + + R K+ E ERR++ E +++ R ++++
Sbjct: 275 EEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEE-ERREQQEERREQQERREQQEE 333
Query: 141 RREMAREHSRRER 153
RRE + ER
Sbjct: 334 RREQQLRREQEER 346
Score = 41.2 bits (95), Expect = 3e-04
Identities = 31/138 (22%), Positives = 69/138 (50%), Gaps = 12/138 (8%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGE---LRDHCMEITIRNSPYRREDSME 74
Q++++R EE+ + +R + +R+ + LEE E R+ ++ ED ++
Sbjct: 804 QQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQL------QEEEDGLQ 857
Query: 75 DRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKARR 134
+ E S + Q+ W+ ++ + +R + ++E+ + ++ +EE+++ +R
Sbjct: 858 EDQERRRSQEQRRDQK--WRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQR 915
Query: 135 EWERQKRREMAREHSRRE 152
E ER+KRR +E RE
Sbjct: 916 E-EREKRRRQEQERQYRE 932
Score = 41.2 bits (95), Expect = 3e-04
Identities = 36/140 (25%), Positives = 70/140 (50%), Gaps = 9/140 (6%)
Query: 18 QEKKRRKEQEEKAEIKRLKNS-DDRDSKRDSLEEGELRDHCMEITIR----NSPYRREDS 72
QE+ R+ +EE+ +R + ++S R EE +LR E +R + YR E+
Sbjct: 1767 QERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEE 1826
Query: 73 MEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEK--WKHARVKEREHERRKRHREEQD 130
E++ L + +Q +E+ ++ +R+E+ W+ K R+ ER ++ REE
Sbjct: 1827 QLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQ-ERERKLREEHI 1885
Query: 131 KARREWERQKRREMAREHSR 150
+ R++ E Q+ R++ S+
Sbjct: 1886 R-RQQKEEQRHRQVGEIKSQ 1904
Score = 40.4 bits (93), Expect = 6e-04
Identities = 25/86 (29%), Positives = 49/86 (56%), Gaps = 4/86 (4%)
Query: 69 REDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREE 128
+E ++DR +E+D + P+ +E+ R+ +KR+E+ + E + E+++R E+
Sbjct: 106 KESLLQDRRQEEDQRRFE-PRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQER-LEQ 163
Query: 129 QDKARREWE--RQKRREMAREHSRRE 152
+D+ RR+ E RQ++ RE R E
Sbjct: 164 RDRQRRDEELWRQRQEWQEREERRAE 189
Score = 40.4 bits (93), Expect = 6e-04
Identities = 37/144 (25%), Positives = 70/144 (48%), Gaps = 10/144 (6%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPY--RREDSMED 75
+++K R+E++ + E + + S ++ LEE ++R E RR++ +
Sbjct: 1553 RDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQ 1612
Query: 76 RGEEDDSLAIKPPQQMSWKEKVH-HRKDEKRK--EKWKHARVKERE----HERRKRHREE 128
+E D + Q + +E+ HR++ RK E+ R +ERE H+R ++ REE
Sbjct: 1613 LRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREE 1672
Query: 129 QDKARREWERQKRREMAREHSRRE 152
++ +E E Q+ R R+ RE
Sbjct: 1673 -EQLLQEGEEQQLRRQERDRKFRE 1695
Score = 40.0 bits (92), Expect = 8e-04
Identities = 31/136 (22%), Positives = 65/136 (47%), Gaps = 9/136 (6%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRG 77
+E++ +E++++A+ + K+ +++ R+ EE R + +R E+ +
Sbjct: 1295 EEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQET------DRKFREEEQLLQER 1348
Query: 78 EEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKARREWE 137
EE + ++ +E H + K E+ + R +ERE RK +EEQ +E E
Sbjct: 1349 EEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERE---RKFLKEEQQLRCQERE 1405
Query: 138 RQKRREMAREHSRRER 153
+Q R++ R+ E+
Sbjct: 1406 QQLRQDRDRKFREEEQ 1421
Score = 39.3 bits (90), Expect = 0.001
Identities = 34/154 (22%), Positives = 72/154 (46%), Gaps = 17/154 (11%)
Query: 15 EILQEKKRRKEQEEKAEIKRLKNSD----DRDSK----RDSLEEGELRDHCMEITIRNSP 66
++ ++++ RK EE+ +++R + DRD K L+EGE + + R+
Sbjct: 1635 QLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGE--EQQLRRQERDRK 1692
Query: 67 YRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERR---- 122
+R E+ R E + + Q + + R++E+ +++ + +++ +E R+
Sbjct: 1693 FREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEE 1752
Query: 123 ---KRHREEQDKARREWERQKRREMAREHSRRER 153
+ REEQ R+E +R+ R E R E+
Sbjct: 1753 EQLRPEREEQQLRRQERDRKFREEEQLRQEREEQ 1786
Score = 38.9 bits (89), Expect = 0.002
Identities = 34/152 (22%), Positives = 70/152 (46%), Gaps = 7/152 (4%)
Query: 3 DEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSL-EEGELRDHCMEIT 61
+E+ + + D +E++ R ++ E+ ++ + + +R L EE +LR
Sbjct: 1489 EEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQ----- 1543
Query: 62 IRNSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHER 121
RR+D EE+ + QQ+S +E+ + E++K + + K E E+
Sbjct: 1544 -ERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQ 1602
Query: 122 RKRHREEQDKARREWERQKRREMAREHSRRER 153
+ R +E Q + R+E +R+ R + R E+
Sbjct: 1603 QLRRQEGQQQLRQERDRKFREDEQLLQEREEQ 1634
Score = 37.7 bits (86), Expect = 0.004
Identities = 36/162 (22%), Positives = 77/162 (47%), Gaps = 25/162 (15%)
Query: 14 DEILQEKKRR---KEQEEKAEIKRLKNSDDRDSKRDS--------------LEEGELRDH 56
+E LQ +KR+ +++++++++K + ++ RD+ LE+ +LRD
Sbjct: 1202 EEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDR 1261
Query: 57 CMEITIRN---SPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHAR 113
+ +++ R+ E R + +Q+ +E+ ++ +++ ++ K
Sbjct: 1262 QSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLL 1321
Query: 114 VKEREHERRKRHREEQDKARREWER--QKRREMAREHSRRER 153
+ERE E KR R+E D+ RE E+ Q+R E R+R
Sbjct: 1322 REERE-E--KRRRQETDRKFREEEQLLQEREEQPLRRQERDR 1360
Score = 37.7 bits (86), Expect = 0.004
Identities = 32/152 (21%), Positives = 74/152 (48%), Gaps = 16/152 (10%)
Query: 15 EILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSME 74
++ ++++ RK EE+ ++++ ++ R+ ++ E E + H E R+ + E+
Sbjct: 1438 QVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQE---RDRKFLEEEQQL 1494
Query: 75 DRGEEDDSL------AIKPPQQMSWKEKVHHRKDEKRK------EKWKHARVKEREHERR 122
R E D + +P ++ +E+ HR+ +RK + + R ++R +R
Sbjct: 1495 RRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRD 1554
Query: 123 KRHREEQD-KARREWERQKRREMAREHSRRER 153
++ REE+ + RE ++ R+E R+ E+
Sbjct: 1555 RKFREEEQLRQEREEQQLSRQERDRKFRLEEQ 1586
Score = 37.7 bits (86), Expect = 0.004
Identities = 32/150 (21%), Positives = 76/150 (50%), Gaps = 11/150 (7%)
Query: 4 EKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIR 63
E+ + + L+ +E+++ +++ E+ +++R ++ R LEE +LR E +R
Sbjct: 1712 EEQQLRRQELERKFREEEQLRQETEQEQLRR------QERYRKILEEEQLRPEREEQQLR 1765
Query: 64 NSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRK 123
R+E + R EE + Q S + R++E+ +++ + +++ ++ + +
Sbjct: 1766 ----RQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKY 1821
Query: 124 RHREEQDKARREWERQKRREMAREHSRRER 153
R EEQ + E E++ R+E R++ E+
Sbjct: 1822 RWEEEQLQLE-EQEQRLRQERDRQYRAEEQ 1850
Score = 37.4 bits (85), Expect = 0.005
Identities = 38/152 (25%), Positives = 75/152 (49%), Gaps = 9/152 (5%)
Query: 9 KVKTLDEILQEKKR----RKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRN 64
K + +++ QE++ R+E++ K ++ K ++ +E +LR + +R
Sbjct: 1556 KFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQ 1615
Query: 65 SPYR--REDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKE-REHER 121
R RED + E+ L + + +E+ R+ E R+++ +H R ++ RE E+
Sbjct: 1616 ERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQE-REQQLRHDRDRKFREEEQ 1674
Query: 122 RKRHREEQDKARREWERQKRREMAREHSRRER 153
+ EEQ R+E +R K RE ++ R+ER
Sbjct: 1675 LLQEGEEQQLRRQERDR-KFREEEQQLRRQER 1705
Score = 37.0 bits (84), Expect = 0.007
Identities = 36/139 (25%), Positives = 70/139 (50%), Gaps = 21/139 (15%)
Query: 18 QEKKRR---KEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSME 74
QE++R+ +EQ+ + + + + DRD K E+ R R+ +R E+ +
Sbjct: 1386 QERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQE------RDRKFREEEQ-Q 1438
Query: 75 DRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKARR 134
R +E + ++ QQ+ R++ RK + + ++ERE + + HR+E+D+
Sbjct: 1439 VRRQERERKFLEEEQQL--------RQERHRKFREEEQLLQEREEQ--QLHRQERDRKFL 1488
Query: 135 EWERQKRREMAREHSRRER 153
E E+Q RR+ R+ RE+
Sbjct: 1489 EEEQQLRRQ-ERDRKFREQ 1506
Score = 36.6 bits (83), Expect = 0.009
Identities = 33/163 (20%), Positives = 72/163 (44%), Gaps = 17/163 (10%)
Query: 4 EKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIR 63
E+ + + ++ L++ + RK +EE+ ++ R +RD K E+ R +
Sbjct: 1395 EEQQLRCQEREQQLRQDRDRKFREEEQQLSR----QERDRKFREEEQQVRRQERERKFLE 1450
Query: 64 NSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRK 123
R++ EE+ L + QQ+ +E+ +E+++ + + K RE E R
Sbjct: 1451 EEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRS 1510
Query: 124 R-------------HREEQDKARREWERQKRREMAREHSRRER 153
+ HR+++ + + E+Q RR+ + R++R
Sbjct: 1511 QEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDR 1553
Score = 36.2 bits (82), Expect = 0.011
Identities = 33/154 (21%), Positives = 73/154 (47%), Gaps = 5/154 (3%)
Query: 3 DEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSL---EEGELRDHCME 59
+E+ + + ++ L+ + RK +EE+ ++ + R +RD EE +LR E
Sbjct: 1647 EEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERE 1706
Query: 60 IT-IRNSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKERE 118
++ R +E + E++ L + Q+ +++ + + E+ + + + + R
Sbjct: 1707 RKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRR 1766
Query: 119 HERRKRHREEQDKARREWERQKRREMAREHSRRE 152
ER ++ REE ++ R+E E Q+ R + RE
Sbjct: 1767 QERDRKFREE-EQLRQEREEQQLRSQESDRKFRE 1799
Score = 35.8 bits (81), Expect = 0.015
Identities = 33/140 (23%), Positives = 67/140 (47%), Gaps = 12/140 (8%)
Query: 14 DEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSM 73
+E+ +++ RK EE+ ++R + ++ EE +LR C E R R++
Sbjct: 1365 EELRHQEQGRKFLEEEQRLRRQERE-----RKFLKEEQQLR--CQE---REQQLRQDRDR 1414
Query: 74 EDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKAR 133
+ R EE+ L+ + + ++E+ + ++R+ K+ + R+ RK EEQ
Sbjct: 1415 KFR-EEEQQLS-RQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQE 1472
Query: 134 REWERQKRREMAREHSRRER 153
RE ++ R+E R+ E+
Sbjct: 1473 REEQQLHRQERDRKFLEEEQ 1492
Score = 35.4 bits (80), Expect = 0.019
Identities = 30/143 (20%), Positives = 71/143 (49%), Gaps = 9/143 (6%)
Query: 15 EILQEKKRRKEQEEKAEIKRLKNS-----DDRDSKRDSLEEGELRDHCMEITIRNSPYRR 69
++ ++++ RK +EE+ +++R + +++ +R LE + + RR
Sbjct: 1683 QLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRR 1742
Query: 70 EDSMEDRGEEDDSLAIKPPQQMSWKEKVHH-RKDEKRKEKWKHARVKEREHERRKRHREE 128
++ EE+ + QQ+ +E+ R++E+ +++ + +++ +E +R+ R EE
Sbjct: 1743 QERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFRE-EE 1801
Query: 129 QDKARREWERQKRREMAREHSRR 151
Q R+E E Q+ R R+ R
Sbjct: 1802 QL--RQEREEQQLRPQQRDGKYR 1822
Score = 32.3 bits (72), Expect = 0.16
Identities = 35/187 (18%), Positives = 83/187 (44%), Gaps = 36/187 (19%)
Query: 3 DEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITI 62
+E++ + + L+ +E++ +++EE+ + + ++ +R EE EL+ ++
Sbjct: 1126 EEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLR 1185
Query: 63 RNSPYRREDSMEDRGEEDDSLAIKPPQQ---------MSWK---EKVHHRKDEK------ 104
RR++ EE++ K Q+ + W+ EK + +D K
Sbjct: 1186 EEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGR 1245
Query: 105 RKEKWKH---ARVKEREHERRKRH------REEQDKARREW---------ERQKRREMAR 146
E+++ +++++R+ ++ +H ++++ RR W E Q RE +
Sbjct: 1246 ENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQK 1305
Query: 147 EHSRRER 153
E RR+R
Sbjct: 1306 EAKRRDR 1312
Score = 31.6 bits (70), Expect = 0.28
Identities = 13/54 (24%), Positives = 33/54 (61%)
Query: 100 RKDEKRKEKWKHARVKEREHERRKRHREEQDKARREWERQKRREMAREHSRRER 153
+++++R+ + + +++E +RR++ R+EQ++ E E Q ++ E R+R
Sbjct: 115 QEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQR 168
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 54.3 bits (129), Expect = 4e-08
Identities = 36/146 (24%), Positives = 73/146 (50%), Gaps = 16/146 (10%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRG 77
+E++R K ++E+ E +R + +++ R S E G R+ E R+ D DR
Sbjct: 177 KEREREKNRQERRERERQREKENKTEDRHS-ERGRERERERETETETERKRQTDRERDRQ 235
Query: 78 EEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKARR--- 134
+ + + ++ + +E+ R+ E+ KE+ + R ++R+ +RR++ RE Q +R
Sbjct: 236 RKTE----REREKQAERERASERETERDKER-ERERDRDRDRDRRQKERERQTDRKRQRR 290
Query: 135 -------EWERQKRREMAREHSRRER 153
E +R+++RE RE R +
Sbjct: 291 TERDRETERKRERQRERERERERNRK 316
Score = 54.3 bits (129), Expect = 4e-08
Identities = 42/138 (30%), Positives = 72/138 (52%), Gaps = 8/138 (5%)
Query: 20 KKRRKEQEEKAEIKRLKNSD-DRDSKRDSLEEGELRDHCMEITIRNSPYRREDSME-DRG 77
++R +E+E + E +R + +D +RD +R + E E + + R + +E E DR
Sbjct: 210 RERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRD 269
Query: 78 EEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHER-RKRHREEQDKARREW 136
+ D + +Q K + +D + + K + R +ERE ER RKR RE + RE
Sbjct: 270 RDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERE----RER 325
Query: 137 ERQKRREMAREHSR-RER 153
ER+++RE R+ + RER
Sbjct: 326 ERERQRETERDREKERER 343
Score = 53.1 bits (126), Expect = 9e-08
Identities = 40/145 (27%), Positives = 68/145 (46%), Gaps = 12/145 (8%)
Query: 21 KRRKEQEEKAEIKRLKNSD---DRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRG 77
+R +E++ AE +R + +D R ++R+ +E E + E R +E+ EDR
Sbjct: 146 QRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRH 205
Query: 78 EED--------DSLAIKPPQQMSWKEKVHHRKDEKRKEKW-KHARVKEREHERRKRHREE 128
E ++ ++ + +E+ RK E+ +EK + R ERE ER K E
Sbjct: 206 SERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERE 265
Query: 129 QDKARREWERQKRREMAREHSRRER 153
+D+ R RQK RE + R+ R
Sbjct: 266 RDRDRDRDRRQKERERQTDRKRQRR 290
Score = 52.0 bits (123), Expect = 2e-07
Identities = 42/160 (26%), Positives = 78/160 (48%), Gaps = 27/160 (16%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGEL-RDHCMEITIRNSPYRREDSMEDR 76
+++K +E+E++AE +R + +R+++RD E E RD + + + + + R
Sbjct: 234 RQRKTEREREKQAERER---ASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRR 290
Query: 77 GEEDDSLAIKPPQQMSW-KEKVHHRKDEKRKEKWKHA-------RVKEREHERRKRHREE 128
E D K +Q +E+ +RK E+ +E+ + R +E+E ER+++ + E
Sbjct: 291 TERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTE 350
Query: 129 QDKAR---------------REWERQKRREMAREHSRRER 153
D+ R RE ER++ R+ ARE RER
Sbjct: 351 MDRERNRQTGREGRRQAERERERERERDRQSAREREERER 390
Score = 51.6 bits (122), Expect = 3e-07
Identities = 36/138 (26%), Positives = 72/138 (52%), Gaps = 8/138 (5%)
Query: 18 QEKKRR-KEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDR 76
Q+++ R K ++E+ E +R + +++ R S E G R+ E R+ D DR
Sbjct: 176 QKEREREKNRQERRERERQREKENKTEDRHS-ERGRERERERETETETERKRQTDRERDR 234
Query: 77 GEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKARREW 136
+ + + ++ + +E+ R+ E+ KE+ + R ++R+ +RR++ RE Q +R+
Sbjct: 235 QRKTE----REREKQAERERASERETERDKER-ERERDRDRDRDRRQKERERQTDRKRQR 289
Query: 137 ERQKRREMAREHSR-RER 153
++ RE R+ R RER
Sbjct: 290 RTERDRETERKRERQRER 307
Score = 49.7 bits (117), Expect = 1e-06
Identities = 39/136 (28%), Positives = 66/136 (48%), Gaps = 15/136 (11%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRG 77
+EK+R ++++ + E+ R +N R + R+ + E R S RE+ DR
Sbjct: 337 REKERERKRKRQTEMDRERN---RQTGREGRRQAERERERERERDRQSAREREERERDRD 393
Query: 78 EEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHER---RKRHREEQDKARR 134
+ K ++ + K++ R+ EK++E R K+RE ER R R RE+Q R
Sbjct: 394 RDRQ----KERERQTEKDRDGQRETEKQRE-----REKDRESERGRERGREREKQKGRER 444
Query: 135 EWERQKRREMAREHSR 150
+ ERQ R+ R+ R
Sbjct: 445 DRERQTDRQAGRQRKR 460
Score = 46.6 bits (109), Expect = 8e-06
Identities = 31/141 (21%), Positives = 74/141 (52%), Gaps = 9/141 (6%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSD-DRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDR 76
+EK+R ++ + + + +R K + ++ +R++ EGE R + + R+ D+ ++R
Sbjct: 101 REKERERQTDRERDRQREKERNRQKERERETEREGE-RGRDRQTDGQRERERQRDAEKER 159
Query: 77 GEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRH----REEQDKA 132
+ D + ++ KE+ +++ R+E+ + R +E+E++ RH RE + +
Sbjct: 160 ERQTDRERQRQTERNRQKER---EREKNRQERRERERQREKENKTEDRHSERGRERERER 216
Query: 133 RREWERQKRREMAREHSRRER 153
E E +++R+ RE R+ +
Sbjct: 217 ETETETERKRQTDRERDRQRK 237
Score = 45.8 bits (107), Expect = 1e-05
Identities = 33/152 (21%), Positives = 64/152 (42%), Gaps = 5/152 (3%)
Query: 4 EKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSD-----DRDSKRDSLEEGELRDHCM 58
E+D + + D +R+KE+E + + KR + ++ +R +R E E +
Sbjct: 257 ERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRK 316
Query: 59 EITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKERE 118
R RE E + + K +Q + + + + + + + R +ERE
Sbjct: 317 RERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERE 376
Query: 119 HERRKRHREEQDKARREWERQKRREMAREHSR 150
+R+ E+ + R+ +RQK RE E R
Sbjct: 377 RDRQSAREREERERDRDRDRQKERERQTEKDR 408
Score = 43.5 bits (101), Expect = 7e-05
Identities = 42/155 (27%), Positives = 73/155 (47%), Gaps = 10/155 (6%)
Query: 3 DEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSD-DRDSKRDSLEEGELRDHCMEIT 61
D K + + E ++++R++E+E + E R + + +R+ +R+ E E RD E
Sbjct: 284 DRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETE-RDREKERE 342
Query: 62 IRNSPYRREDSMEDR--GEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREH 119
+ D +R G E A + ++ +++ R+ E+R+ R KERE
Sbjct: 343 RKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERE- 401
Query: 120 ERRKRHREEQDKARREWERQKRREMAREHSR-RER 153
R E+ +RE E+Q+ RE RE R RER
Sbjct: 402 ----RQTEKDRDGQRETEKQREREKDRESERGRER 432
Score = 42.4 bits (98), Expect = 2e-04
Identities = 45/170 (26%), Positives = 79/170 (46%), Gaps = 23/170 (13%)
Query: 4 EKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSD---DRDSKRDSLEEGELRDHCMEI 60
E++ + K E ++KR + +E+ KR ++ + DR+ +R+ + E RD E
Sbjct: 61 ERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRE-RDRQREK 119
Query: 61 TIRNSPYRREDSMEDRGE-----EDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVK 115
RN RE E GE + D + Q+ + KE+ + D +R+ + + R K
Sbjct: 120 E-RNRQKERERETEREGERGRDRQTDGQRERERQRDAEKER-ERQTDRERQRQTERNRQK 177
Query: 116 EREHER---------RKRHREEQDKAR---REWERQKRREMAREHSRRER 153
ERE E+ R+R +E + + R R ER++ RE E R+ +
Sbjct: 178 EREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQ 227
Score = 41.6 bits (96), Expect = 3e-04
Identities = 39/155 (25%), Positives = 75/155 (48%), Gaps = 39/155 (25%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRG 77
+E+ R+KE+E + E ++ + DR KR+ E + +R+ D +R
Sbjct: 54 RERNRQKERERRREKRQTERETDR--KRERRREKDR-------------HRKRDRHRERQ 98
Query: 78 EEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHER---------RKRHRE- 127
+ + K ++ + +E+ R+ E+ ++K + R ERE ER R+R R+
Sbjct: 99 RDRE----KERERQTDRERDRQREKERNRQK-ERERETEREGERGRDRQTDGQRERERQR 153
Query: 128 --EQDKAR-------REWERQKRREMAREHSRRER 153
E+++ R R+ ER +++E RE +R+ER
Sbjct: 154 DAEKERERQTDRERQRQTERNRQKEREREKNRQER 188
Score = 40.4 bits (93), Expect = 6e-04
Identities = 41/143 (28%), Positives = 70/143 (48%), Gaps = 12/143 (8%)
Query: 17 LQEKKRRKEQEEKAEIKRL----KNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDS 72
L +RR +E + L K++D D +R+ +E E R + T R + +RE
Sbjct: 24 LDFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQ-TERETDRKRERR 82
Query: 73 ME-DRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRK---RHREE 128
E DR + D + + +E+ R+ ++++EK ++ R KERE E + R R+
Sbjct: 83 REKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERN-RQKERERETEREGERGRDR 141
Query: 129 QDKARREWERQKRREMAREHSRR 151
Q +RE ERQ R+ +E R+
Sbjct: 142 QTDGQRERERQ--RDAEKERERQ 162
Score = 39.3 bits (90), Expect = 0.001
Identities = 32/138 (23%), Positives = 67/138 (48%), Gaps = 11/138 (7%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSD---DRDSKRDSLEEGELRDHCMEITIRNSPYRREDSME 74
+ +KR +E+E + E +R + ++ +++ +R + E+ T R + E E
Sbjct: 313 RNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERE 372
Query: 75 DRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKAR- 133
E D A + ++ +++ ++ E++ EK R +RE E+++ ++++ R
Sbjct: 373 RERERDRQSAREREERERDRDRDRQKERERQTEK---DRDGQRETEKQREREKDRESERG 429
Query: 134 ----REWERQKRREMARE 147
RE E+QK RE RE
Sbjct: 430 RERGREREKQKGRERDRE 447
Score = 30.4 bits (67), Expect = 0.62
Identities = 16/47 (34%), Positives = 25/47 (53%), Gaps = 3/47 (6%)
Query: 110 KHARVKEREHERRKRHREEQDKARREWERQKRREMARE---HSRRER 153
K A +RE R+K ++K + E E ++RE RE H +R+R
Sbjct: 47 KDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDR 93
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 53.5 bits (127), Expect = 7e-08
Identities = 32/137 (23%), Positives = 66/137 (48%), Gaps = 24/137 (17%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRG 77
++KK++KE EE E + + ++++ K R+E E R
Sbjct: 2 KKKKKKKETEETEETEETEEEEEKEGK-----------------------RKEKRKEKRK 38
Query: 78 EEDDSLAIKPPQQMSWKEKVH-HRKDEKRKEKWKHARVKEREHERRKRHREEQDKARREW 136
E++ K ++ KE+ RK +++K+K + R +E E E ++ EE+++ RR
Sbjct: 39 EKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRK 98
Query: 137 ERQKRREMAREHSRRER 153
+++KRR E ++++
Sbjct: 99 KKKKRRRKEEEEEKKKK 115
Score = 47.4 bits (111), Expect = 5e-06
Identities = 32/121 (26%), Positives = 60/121 (49%), Gaps = 15/121 (12%)
Query: 11 KTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRRE 70
+T +E +E KR+++++EK + K K KR EE E + R +++
Sbjct: 18 ETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK--------RKRKRKKK 69
Query: 71 DSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQD 130
E+R EE++ ++ KE+ + +RK+K K R +E E +++KR R+ +
Sbjct: 70 KEEEEREEEEE-------EEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKK 122
Query: 131 K 131
K
Sbjct: 123 K 123
Score = 35.0 bits (79), Expect = 0.025
Identities = 29/128 (22%), Positives = 51/128 (39%), Gaps = 40/128 (31%)
Query: 4 EKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIR 63
EK K K EK++ KE+EEK ++ K + + + + EE E
Sbjct: 35 EKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEE----------- 83
Query: 64 NSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRK 123
E++ EE+ +++ +R++K K R KE E E++K
Sbjct: 84 ----------EEKEEEE-------------------KEEGRRRKKKKKRRRKEEEEEKKK 114
Query: 124 RHREEQDK 131
+ R + K
Sbjct: 115 KRRRKTKK 122
Score = 33.9 bits (76), Expect = 0.056
Identities = 17/64 (26%), Positives = 35/64 (54%), Gaps = 4/64 (6%)
Query: 94 KEKVHHRKDEKRKEKWKHARVKEREHERRKRHR----EEQDKARREWERQKRREMAREHS 149
K+K +K+ + E+ + +E + +RK R +E++K ++ E +KR+E E
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60
Query: 150 RRER 153
+R+R
Sbjct: 61 KRKR 64
>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
Length = 953
Score = 53.1 bits (126), Expect = 9e-08
Identities = 48/163 (29%), Positives = 78/163 (47%), Gaps = 24/163 (14%)
Query: 15 EILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEIT--IRNSP------ 66
E+L++ RKEQE E KR + D + E RD I +R++
Sbjct: 310 EVLKKATIRKEQEPDFEEKRFTVTIGEDEREFDKENEVFRDWNSRIPRDVRDTVLEPYAD 369
Query: 67 --YRREDSMEDRGEEDDSLAIKPPQQM---SWKEKVHHRKDEKRKEKWKHARVKEREHER 121
Y E RG + ++ ++ + +++E+ R+ E R+ + + R ++RE ER
Sbjct: 370 PYYDYEIERFWRGGQYENFRVQYTETEPYHNYRERERERERENRQRERERERERDRERER 429
Query: 122 RKRHRE-----EQDKARR----EWERQ--KRREMAREHSRRER 153
R+R RE E+DK R+ EWER+ KR E R+H R+R
Sbjct: 430 RQREREREREHERDKERQRRKEEWERERAKRDEKDRQHRDRDR 472
Score = 38.1 bits (87), Expect = 0.003
Identities = 21/83 (25%), Positives = 40/83 (48%), Gaps = 3/83 (3%)
Query: 63 RNSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKD---EKRKEKWKHARVKEREH 119
R RE+ +R E + + +Q + + H +D ++RKE+W+ R K E
Sbjct: 404 RERERERENRQRERERERERDRERERRQREREREREHERDKERQRRKEEWERERAKRDEK 463
Query: 120 ERRKRHREEQDKARREWERQKRR 142
+R+ R R+ + + +E + K R
Sbjct: 464 DRQHRDRDREKEREKEKGKPKPR 486
Score = 34.7 bits (78), Expect = 0.033
Identities = 29/124 (23%), Positives = 50/124 (40%), Gaps = 25/124 (20%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRG 77
+E++R +E+E + + + DR+ +R E R+H R+ + R
Sbjct: 402 RERERERERENRQRERERERERDRERERRQREREREREH-----------ERDKERQRRK 450
Query: 78 EEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKARREWE 137
EE W E+ ++DEK ++ R KERE E+ K R+ E
Sbjct: 451 EE-------------W-ERERAKRDEKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAE 496
Query: 138 RQKR 141
K+
Sbjct: 497 PPKK 500
Score = 29.3 bits (64), Expect = 1.4
Identities = 15/41 (36%), Positives = 24/41 (58%), Gaps = 6/41 (14%)
Query: 15 EILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRD 55
E L+ K +K++++ EI DD + D LEEGE++D
Sbjct: 178 ESLEAAKEKKKEDDDGEI------DDGEIDDDDLEEGEVKD 212
Score = 28.1 bits (61), Expect = 3.1
Identities = 30/108 (27%), Positives = 46/108 (42%), Gaps = 16/108 (14%)
Query: 26 QEEKAEIKRLKNSDDRD---SKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGEEDDS 82
+EE E + + SD RD S L+E EL D+ E+ +P +ED E G EDD
Sbjct: 98 EEEGDEGEEDRTSDLRDEASSVTRELDEHEL-DYDEEVPEEPAPAVQEDEAEKAGAEDD- 155
Query: 83 LAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQD 130
+EK E+ K + KE +++ +E+ D
Sbjct: 156 -----------EEKGEGTPREEGKAGVQSVGEKESLEAAKEKKKEDDD 192
>gi|62244004 modulator of estrogen induced transcription isoform b
[Homo sapiens]
Length = 1016
Score = 52.4 bits (124), Expect = 2e-07
Identities = 48/170 (28%), Positives = 82/170 (48%), Gaps = 25/170 (14%)
Query: 2 GDEKDSW--KVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCME 59
GD+K++ KT + +E+KR E+ EK E K K + +D K D+ G+ +
Sbjct: 465 GDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKIEGKDEKNDNGASGQTSE---- 520
Query: 60 ITIRNSPYRREDSMEDRG-----EEDDSLAIKPPQQMSWKEKVHHRKDEKR-----KEKW 109
+I+ S ++ S + G ++ +P ++ + EK+H R EK K++
Sbjct: 521 -SIKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRY-EKIHGRSKEKERASLDKKRD 578
Query: 110 KHARVKE------REHERRKRHREEQDKARREWERQKRREMAREHSRRER 153
K R KE + +R + H ++ RR E ++RRE+A E RRER
Sbjct: 579 KDYRRKEILPFEKMKEQRLREHLVRFERLRRAMELRRRREIA-ERERRER 627
Score = 38.9 bits (89), Expect = 0.002
Identities = 35/138 (25%), Positives = 67/138 (48%), Gaps = 15/138 (10%)
Query: 23 RKEQEEKAEIKRLKNSDDRDSKR---DSLEEGELRDHCMEITIRNSPYRREDSMEDRGEE 79
R +++E+A + + ++ D R + + ++E LR+H +R RR + R E
Sbjct: 564 RSKEKERASLDKKRDKDYRRKEILPFEKMKEQRLREHL----VRFERLRRAMELRRRRE- 618
Query: 80 DDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKER---EHERRKRHREEQDKARREW 136
+A + ++ + R++ +R ++ + ER E ER +R R E+++ R E
Sbjct: 619 ---IAERERRERERIRIIREREERERLQRERERLEIERQKLERERMERERLERERIRIEQ 675
Query: 137 ERQKRRE-MAREHSRRER 153
ER+K E +ARE R
Sbjct: 676 ERRKEAERIAREREELRR 693
Score = 33.1 bits (74), Expect = 0.095
Identities = 35/146 (23%), Positives = 64/146 (43%), Gaps = 16/146 (10%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDR-------DSKRDSLEEGELRDHCMEITIRNSPYRRE 70
Q+++ R EQE++ +KR ++ D R ++K+ SL+ H + + + + +
Sbjct: 694 QQQQLRYEQEKRNSLKRPRDVDHRRDDPYWSENKKLSLDTDARFGHGSDYSRQQNRFNDF 753
Query: 71 DSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRH----- 125
D E RG +S A+ Q S++ + + K+ AR ++ ER ++
Sbjct: 754 DHRE-RGRFPESSAV---QSSSFERRDRFVGQSEGKKARPTARREDPSFERYPKNFSDSR 809
Query: 126 REEQDKARREWERQKRREMAREHSRR 151
R E R E RRE+ E R
Sbjct: 810 RNEPPPPRNELRESDRREVRGERDER 835
>gi|63176611 modulator of estrogen induced transcription isoform a
[Homo sapiens]
Length = 1034
Score = 52.4 bits (124), Expect = 2e-07
Identities = 48/170 (28%), Positives = 82/170 (48%), Gaps = 25/170 (14%)
Query: 2 GDEKDSW--KVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCME 59
GD+K++ KT + +E+KR E+ EK E K K + +D K D+ G+ +
Sbjct: 483 GDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKIEGKDEKNDNGASGQTSE---- 538
Query: 60 ITIRNSPYRREDSMEDRG-----EEDDSLAIKPPQQMSWKEKVHHRKDEKR-----KEKW 109
+I+ S ++ S + G ++ +P ++ + EK+H R EK K++
Sbjct: 539 -SIKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRY-EKIHGRSKEKERASLDKKRD 596
Query: 110 KHARVKE------REHERRKRHREEQDKARREWERQKRREMAREHSRRER 153
K R KE + +R + H ++ RR E ++RRE+A E RRER
Sbjct: 597 KDYRRKEILPFEKMKEQRLREHLVRFERLRRAMELRRRREIA-ERERRER 645
Score = 38.9 bits (89), Expect = 0.002
Identities = 35/138 (25%), Positives = 67/138 (48%), Gaps = 15/138 (10%)
Query: 23 RKEQEEKAEIKRLKNSDDRDSKR---DSLEEGELRDHCMEITIRNSPYRREDSMEDRGEE 79
R +++E+A + + ++ D R + + ++E LR+H +R RR + R E
Sbjct: 582 RSKEKERASLDKKRDKDYRRKEILPFEKMKEQRLREHL----VRFERLRRAMELRRRRE- 636
Query: 80 DDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKER---EHERRKRHREEQDKARREW 136
+A + ++ + R++ +R ++ + ER E ER +R R E+++ R E
Sbjct: 637 ---IAERERRERERIRIIREREERERLQRERERLEIERQKLERERMERERLERERIRIEQ 693
Query: 137 ERQKRRE-MAREHSRRER 153
ER+K E +ARE R
Sbjct: 694 ERRKEAERIAREREELRR 711
Score = 33.1 bits (74), Expect = 0.095
Identities = 35/146 (23%), Positives = 64/146 (43%), Gaps = 16/146 (10%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDR-------DSKRDSLEEGELRDHCMEITIRNSPYRRE 70
Q+++ R EQE++ +KR ++ D R ++K+ SL+ H + + + + +
Sbjct: 712 QQQQLRYEQEKRNSLKRPRDVDHRRDDPYWSENKKLSLDTDARFGHGSDYSRQQNRFNDF 771
Query: 71 DSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRH----- 125
D E RG +S A+ Q S++ + + K+ AR ++ ER ++
Sbjct: 772 DHRE-RGRFPESSAV---QSSSFERRDRFVGQSEGKKARPTARREDPSFERYPKNFSDSR 827
Query: 126 REEQDKARREWERQKRREMAREHSRR 151
R E R E RRE+ E R
Sbjct: 828 RNEPPPPRNELRESDRREVRGERDER 853
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 52.0 bits (123), Expect = 2e-07
Identities = 43/156 (27%), Positives = 75/156 (48%), Gaps = 8/156 (5%)
Query: 3 DEKDSWKVKTLDEILQEKKRR-KEQEEKAEIKRLKNSDDRDSKRDSLEEGEL---RDHCM 58
+E+ K K EI +E++ R +E+E + E + + +R+ +R+ +E E RD
Sbjct: 292 EEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRDR 351
Query: 59 EITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKERE 118
+ T R + DR E S K + K + R+ E+ +E+ R +ERE
Sbjct: 352 DRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERER---ERERERE 408
Query: 119 HER-RKRHREEQDKARREWERQKRREMAREHSRRER 153
ER R+R RE + + RE ++++ RE E + R
Sbjct: 409 REREREREREREREREREKDKKRDREEDEEDAYERR 444
Score = 50.1 bits (118), Expect = 8e-07
Identities = 38/140 (27%), Positives = 71/140 (50%), Gaps = 6/140 (4%)
Query: 18 QEKKRRKEQE-EKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDR 76
+E++R +E+E E+ + K + +RD RD +E + RD E R D +DR
Sbjct: 323 REREREREREREREKEKERERERERDRDRDRTKERD-RDRDRERDRDRDRERSSDRNKDR 381
Query: 77 GEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHER---RKRHREEQDKAR 133
+ + ++ +E+ R+ E+ +E+ + R +ERE ER +KR REE ++
Sbjct: 382 SRSREKSRDRERERERERERERERERERERER-EREREREREREREKDKKRDREEDEEDA 440
Query: 134 REWERQKRREMAREHSRRER 153
E + +R+ +E + +ER
Sbjct: 441 YERRKLERKLREKEAAYQER 460
Score = 48.5 bits (114), Expect = 2e-06
Identities = 37/146 (25%), Positives = 70/146 (47%), Gaps = 6/146 (4%)
Query: 9 KVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYR 68
K + + L+E+K +KE+E + EI++ + +R+ +R+ R+ E R
Sbjct: 283 KFRDTHKKLEEEKGKKEKERQ-EIEKERRERERERERERERREREREREREREREKEKER 341
Query: 69 REDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREE 128
+ DR + + + +++ R ++ K++ +R K R+ R+R RE
Sbjct: 342 ERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDR-SRSREKSRD---RERERER 397
Query: 129 QDKARREWERQKRREMAREHSR-RER 153
+ + RE ER++ RE RE R RER
Sbjct: 398 ERERERERERERERERERERERERER 423
Score = 48.5 bits (114), Expect = 2e-06
Identities = 42/151 (27%), Positives = 66/151 (43%), Gaps = 7/151 (4%)
Query: 4 EKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIR 63
++D + K D ++ R E++ + S R+ RD E E R+ E
Sbjct: 348 DRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERE-RERERERERE 406
Query: 64 NSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKER----EH 119
R + +R E + K + +E + R+ +RK + K A +ER E
Sbjct: 407 REREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEI 466
Query: 120 ERRKRHREEQDKARREWERQKRREMAREHSR 150
RK+ RE + +A RE ER RREMA+E R
Sbjct: 467 RERKKTREYEKEAEREEER--RREMAKEAKR 495
Score = 48.1 bits (113), Expect = 3e-06
Identities = 45/157 (28%), Positives = 70/157 (44%), Gaps = 20/157 (12%)
Query: 14 DEILQEKKRRKEQEEKAEIKRLKN---------SDDRDS----KRDSLEEGELRDHCMEI 60
+E L E+ +R++Q K I+ L S + DS K+ +E R +
Sbjct: 193 EEALDEETKRRDQMIKGAIEVLIREYSSELNAPSQESDSHPRKKKKEKKEDIFRRFPVAP 252
Query: 61 TIRNSPYRREDSMEDRGEED--DSLAIKPPQQMSWKEKVHHRKDEKRKE-----KWKHAR 113
I +ED EED D ++ + + +K+ K +K KE K + R
Sbjct: 253 LIPYPLITKEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRER 312
Query: 114 VKEREHERRKRHREEQDKARREWERQKRREMAREHSR 150
+ERE ER +R RE + + RE E++K RE RE R
Sbjct: 313 ERERERERERREREREREREREREKEKERERERERDR 349
Score = 45.8 bits (107), Expect = 1e-05
Identities = 43/162 (26%), Positives = 72/162 (44%), Gaps = 30/162 (18%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRG 77
+E++R +E+E + E +R + +RD RD +E + RD E R D +DR
Sbjct: 325 REREREREREREKEKER-ERERERDRDRDRTKERD-RDRDRERDRDRDRERSSDRNKDRS 382
Query: 78 EEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHER---RKRHREEQDKARR 134
+ + ++ +E+ R+ E+ +E+ + R +ERE ER +KR REE ++
Sbjct: 383 RSREKSRDRERERERERERERERERERERER-EREREREREREREKDKKRDREEDEEDAY 441
Query: 135 E---------------------WE---RQKRREMAREHSRRE 152
E WE R+K RE +E R E
Sbjct: 442 ERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREE 483
Score = 37.7 bits (86), Expect = 0.004
Identities = 34/134 (25%), Positives = 63/134 (47%), Gaps = 6/134 (4%)
Query: 26 QEEKAEIKRLKNSDDRDS-KRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGEEDDSLA 84
+E+K ++ + S RD+ K+ E+G+ EI RE E E +
Sbjct: 270 EEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERERER 329
Query: 85 IKPPQQMSWKEKVHHRKDEKRKEKWKHA---RVKEREHERRKRHREEQDKAR-REWERQK 140
+ ++ KE+ R+ ++ +++ K R +ER+ +R + +++K R R E+ +
Sbjct: 330 EREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSR 389
Query: 141 RREMAREHSR-RER 153
RE RE R RER
Sbjct: 390 DRERERERERERER 403
Score = 35.8 bits (81), Expect = 0.015
Identities = 28/117 (23%), Positives = 61/117 (52%), Gaps = 5/117 (4%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSD-DRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDR 76
+EK R +E+E + E +R + + +R+ +R+ E E R+ E ++ RE+ ED
Sbjct: 385 REKSRDRERERERERERERERERERERERERERERE-RERERE---KDKKRDREEDEEDA 440
Query: 77 GEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKAR 133
E ++ +++E++ + + +RK+ ++ + ERE ERR+ +E + +
Sbjct: 441 YERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLK 497
Score = 35.4 bits (80), Expect = 0.019
Identities = 44/175 (25%), Positives = 78/175 (44%), Gaps = 32/175 (18%)
Query: 3 DEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGEL-RDHCMEIT 61
DE+D+++ + L+ L+EK E A +RLKN + R+ K+ E E R+
Sbjct: 436 DEEDAYERRKLERKLREK-------EAAYQERLKNWEIRERKKTREYEKEAEREEERRRE 488
Query: 62 IRNSPYRREDSMEDRGEEDDS------LAIKPPQQMSWKEKVHHRKDEKR-KEKWKHARV 114
+ R ++ +ED ++ D A++ + KE +D KR KE+ + R
Sbjct: 489 MAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQ 548
Query: 115 K----------------EREHERRKRHREEQDKARREWERQKR-REMAREHSRRE 152
+ E+E ERR++ + +Q+ E E +K+ +E RE E
Sbjct: 549 RLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEE 603
Score = 33.1 bits (74), Expect = 0.095
Identities = 27/102 (26%), Positives = 44/102 (43%), Gaps = 9/102 (8%)
Query: 17 LQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDR 76
LQ++ R +E+E +A D+RD KR+ E E+R + P ME
Sbjct: 518 LQKRLRDREKEMEA--------DERDRKREKEELEEIRQRLLAEG-HPDPDAELQRMEQE 568
Query: 77 GEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKERE 118
E IK + +E+ K+EKR+E + E++
Sbjct: 569 AERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQK 610
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 51.6 bits (122), Expect = 3e-07
Identities = 36/138 (26%), Positives = 73/138 (52%), Gaps = 11/138 (7%)
Query: 18 QEKKRRKEQEEKAEIKR---LKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSME 74
+E+++R+E+EE A K+ L+ +++ E E R E R RRE+ E
Sbjct: 768 EEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREE--E 825
Query: 75 DRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKARR 134
+R ++++ L + + W R++E+ + + + R++ E R RH EE+ K R+
Sbjct: 826 ERRKQEELLRKQEEEAAKWA-----REEEEAQRRLEENRLRMEEEAARLRHEEEERK-RK 879
Query: 135 EWERQKRREMAREHSRRE 152
E E Q+++E+ R+ +++
Sbjct: 880 ELEVQRQKELMRQRQQQQ 897
Score = 37.4 bits (85), Expect = 0.005
Identities = 29/90 (32%), Positives = 47/90 (52%), Gaps = 6/90 (6%)
Query: 68 RREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDE---KRKEKWKHARVKEREHERRKR 124
RRE M + EE++ + + +E++ R+ E KR+E+ + AR K+ E RR+R
Sbjct: 735 RREAEMRAKREEEERK--RQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQR 792
Query: 125 HRE-EQDKARREWERQKRREMAREHSRRER 153
+E + R E ERQ++ E R R R
Sbjct: 793 EQEIALRRQREEEERQQQEEALRRLEERRR 822
Score = 35.8 bits (81), Expect = 0.015
Identities = 30/133 (22%), Positives = 61/133 (45%), Gaps = 15/133 (11%)
Query: 17 LQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDR 76
L++ K K ++E+ E + ++ + KR ELR EI RR+ E +
Sbjct: 723 LEKAKAAKLEQERREAEMRAKREEEERKRQE----ELRRQQEEIL------RRQQEEERK 772
Query: 77 GEEDDSLAIKPPQQMSWKEKVHH---RKDEKRKEKWKHARVKEREHERRKRHREEQDKAR 133
E++ LA + ++ +++ R+ + +E+ + R ERR+ EE+ + +
Sbjct: 773 RREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRRE--EEERRKQ 830
Query: 134 REWERQKRREMAR 146
E R++ E A+
Sbjct: 831 EELLRKQEEEAAK 843
Score = 35.8 bits (81), Expect = 0.015
Identities = 33/167 (19%), Positives = 76/167 (45%), Gaps = 27/167 (16%)
Query: 10 VKTLDEILQEKKRRKEQEE---KAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSP 66
++ L+E +E++ R++QEE K E + K + + + + LEE LR +R+
Sbjct: 814 LRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEE 873
Query: 67 ----------YRREDSMEDRGEEDDSLA-------------IKPPQQMSWKEKVHHRKDE 103
R+++ M R ++ ++L +K P +W ++ + +
Sbjct: 874 EERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQ 933
Query: 104 KRKEKWKHARVKEREHERRKRHREEQDKARREWERQKRREMAREHSR 150
+ A +++ E ER ++ REEQ + +RE + +++ ++ +
Sbjct: 934 SQATL-SLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQK 979
Score = 33.5 bits (75), Expect = 0.073
Identities = 19/67 (28%), Positives = 40/67 (59%), Gaps = 2/67 (2%)
Query: 89 QQMSWKEKVHHRK-DEKRKEKWKHARVKEREHERRKRHREEQDKA-RREWERQKRREMAR 146
+Q+ EK K +++R+E A+ +E E +R++ R +Q++ RR+ E +++R
Sbjct: 718 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 777
Query: 147 EHSRRER 153
E +RR++
Sbjct: 778 ELARRKQ 784
Score = 32.3 bits (72), Expect = 0.16
Identities = 17/80 (21%), Positives = 40/80 (50%)
Query: 73 MEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKA 132
+E E + A + ++ +E++ +++E + + + R + E E +R +EE +
Sbjct: 731 LEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRR 790
Query: 133 RREWERQKRREMAREHSRRE 152
+RE E RR+ E +++
Sbjct: 791 QREQEIALRRQREEEERQQQ 810
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
sapiens]
Length = 1320
Score = 51.6 bits (122), Expect = 3e-07
Identities = 36/138 (26%), Positives = 73/138 (52%), Gaps = 11/138 (7%)
Query: 18 QEKKRRKEQEEKAEIKR---LKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSME 74
+E+++R+E+EE A K+ L+ +++ E E R E R RRE+ E
Sbjct: 795 EEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREE--E 852
Query: 75 DRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKARR 134
+R ++++ L + + W R++E+ + + + R++ E R RH EE+ K R+
Sbjct: 853 ERRKQEELLRKQEEEAAKWA-----REEEEAQRRLEENRLRMEEEAARLRHEEEERK-RK 906
Query: 135 EWERQKRREMAREHSRRE 152
E E Q+++E+ R+ +++
Sbjct: 907 ELEVQRQKELMRQRQQQQ 924
Score = 37.4 bits (85), Expect = 0.005
Identities = 29/90 (32%), Positives = 47/90 (52%), Gaps = 6/90 (6%)
Query: 68 RREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDE---KRKEKWKHARVKEREHERRKR 124
RRE M + EE++ + + +E++ R+ E KR+E+ + AR K+ E RR+R
Sbjct: 762 RREAEMRAKREEEERK--RQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQR 819
Query: 125 HRE-EQDKARREWERQKRREMAREHSRRER 153
+E + R E ERQ++ E R R R
Sbjct: 820 EQEIALRRQREEEERQQQEEALRRLEERRR 849
Score = 35.8 bits (81), Expect = 0.015
Identities = 30/133 (22%), Positives = 61/133 (45%), Gaps = 15/133 (11%)
Query: 17 LQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDR 76
L++ K K ++E+ E + ++ + KR ELR EI RR+ E +
Sbjct: 750 LEKAKAAKLEQERREAEMRAKREEEERKRQE----ELRRQQEEIL------RRQQEEERK 799
Query: 77 GEEDDSLAIKPPQQMSWKEKVHH---RKDEKRKEKWKHARVKEREHERRKRHREEQDKAR 133
E++ LA + ++ +++ R+ + +E+ + R ERR+ EE+ + +
Sbjct: 800 RREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRRE--EEERRKQ 857
Query: 134 REWERQKRREMAR 146
E R++ E A+
Sbjct: 858 EELLRKQEEEAAK 870
Score = 35.8 bits (81), Expect = 0.015
Identities = 33/167 (19%), Positives = 76/167 (45%), Gaps = 27/167 (16%)
Query: 10 VKTLDEILQEKKRRKEQEE---KAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSP 66
++ L+E +E++ R++QEE K E + K + + + + LEE LR +R+
Sbjct: 841 LRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEE 900
Query: 67 ----------YRREDSMEDRGEEDDSLA-------------IKPPQQMSWKEKVHHRKDE 103
R+++ M R ++ ++L +K P +W ++ + +
Sbjct: 901 EERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQ 960
Query: 104 KRKEKWKHARVKEREHERRKRHREEQDKARREWERQKRREMAREHSR 150
+ A +++ E ER ++ REEQ + +RE + +++ ++ +
Sbjct: 961 SQATL-SLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQK 1006
Score = 33.5 bits (75), Expect = 0.073
Identities = 19/67 (28%), Positives = 40/67 (59%), Gaps = 2/67 (2%)
Query: 89 QQMSWKEKVHHRK-DEKRKEKWKHARVKEREHERRKRHREEQDKA-RREWERQKRREMAR 146
+Q+ EK K +++R+E A+ +E E +R++ R +Q++ RR+ E +++R
Sbjct: 745 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 804
Query: 147 EHSRRER 153
E +RR++
Sbjct: 805 ELARRKQ 811
Score = 32.3 bits (72), Expect = 0.16
Identities = 17/80 (21%), Positives = 40/80 (50%)
Query: 73 MEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKA 132
+E E + A + ++ +E++ +++E + + + R + E E +R +EE +
Sbjct: 758 LEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRR 817
Query: 133 RREWERQKRREMAREHSRRE 152
+RE E RR+ E +++
Sbjct: 818 QREQEIALRRQREEEERQQQ 837
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 51.6 bits (122), Expect = 3e-07
Identities = 36/138 (26%), Positives = 73/138 (52%), Gaps = 11/138 (7%)
Query: 18 QEKKRRKEQEEKAEIKR---LKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSME 74
+E+++R+E+EE A K+ L+ +++ E E R E R RRE+ E
Sbjct: 774 EEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREE--E 831
Query: 75 DRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKARR 134
+R ++++ L + + W R++E+ + + + R++ E R RH EE+ K R+
Sbjct: 832 ERRKQEELLRKQEEEAAKWA-----REEEEAQRRLEENRLRMEEEAARLRHEEEERK-RK 885
Query: 135 EWERQKRREMAREHSRRE 152
E E Q+++E+ R+ +++
Sbjct: 886 ELEVQRQKELMRQRQQQQ 903
Score = 37.4 bits (85), Expect = 0.005
Identities = 29/90 (32%), Positives = 47/90 (52%), Gaps = 6/90 (6%)
Query: 68 RREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDE---KRKEKWKHARVKEREHERRKR 124
RRE M + EE++ + + +E++ R+ E KR+E+ + AR K+ E RR+R
Sbjct: 741 RREAEMRAKREEEERK--RQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQR 798
Query: 125 HRE-EQDKARREWERQKRREMAREHSRRER 153
+E + R E ERQ++ E R R R
Sbjct: 799 EQEIALRRQREEEERQQQEEALRRLEERRR 828
Score = 35.8 bits (81), Expect = 0.015
Identities = 30/133 (22%), Positives = 61/133 (45%), Gaps = 15/133 (11%)
Query: 17 LQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDR 76
L++ K K ++E+ E + ++ + KR ELR EI RR+ E +
Sbjct: 729 LEKAKAAKLEQERREAEMRAKREEEERKRQE----ELRRQQEEIL------RRQQEEERK 778
Query: 77 GEEDDSLAIKPPQQMSWKEKVHH---RKDEKRKEKWKHARVKEREHERRKRHREEQDKAR 133
E++ LA + ++ +++ R+ + +E+ + R ERR+ EE+ + +
Sbjct: 779 RREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRRE--EEERRKQ 836
Query: 134 REWERQKRREMAR 146
E R++ E A+
Sbjct: 837 EELLRKQEEEAAK 849
Score = 35.8 bits (81), Expect = 0.015
Identities = 33/167 (19%), Positives = 76/167 (45%), Gaps = 27/167 (16%)
Query: 10 VKTLDEILQEKKRRKEQEE---KAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSP 66
++ L+E +E++ R++QEE K E + K + + + + LEE LR +R+
Sbjct: 820 LRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEE 879
Query: 67 ----------YRREDSMEDRGEEDDSLA-------------IKPPQQMSWKEKVHHRKDE 103
R+++ M R ++ ++L +K P +W ++ + +
Sbjct: 880 EERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQ 939
Query: 104 KRKEKWKHARVKEREHERRKRHREEQDKARREWERQKRREMAREHSR 150
+ A +++ E ER ++ REEQ + +RE + +++ ++ +
Sbjct: 940 SQATL-SLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQK 985
Score = 33.5 bits (75), Expect = 0.073
Identities = 19/67 (28%), Positives = 40/67 (59%), Gaps = 2/67 (2%)
Query: 89 QQMSWKEKVHHRK-DEKRKEKWKHARVKEREHERRKRHREEQDKA-RREWERQKRREMAR 146
+Q+ EK K +++R+E A+ +E E +R++ R +Q++ RR+ E +++R
Sbjct: 724 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 783
Query: 147 EHSRRER 153
E +RR++
Sbjct: 784 ELARRKQ 790
Score = 32.3 bits (72), Expect = 0.16
Identities = 17/80 (21%), Positives = 40/80 (50%)
Query: 73 MEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKA 132
+E E + A + ++ +E++ +++E + + + R + E E +R +EE +
Sbjct: 737 LEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRR 796
Query: 133 RREWERQKRREMAREHSRRE 152
+RE E RR+ E +++
Sbjct: 797 QREQEIALRRQREEEERQQQ 816
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 51.6 bits (122), Expect = 3e-07
Identities = 36/138 (26%), Positives = 73/138 (52%), Gaps = 11/138 (7%)
Query: 18 QEKKRRKEQEEKAEIKR---LKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSME 74
+E+++R+E+EE A K+ L+ +++ E E R E R RRE+ E
Sbjct: 774 EEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREE--E 831
Query: 75 DRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKARR 134
+R ++++ L + + W R++E+ + + + R++ E R RH EE+ K R+
Sbjct: 832 ERRKQEELLRKQEEEAAKWA-----REEEEAQRRLEENRLRMEEEAARLRHEEEERK-RK 885
Query: 135 EWERQKRREMAREHSRRE 152
E E Q+++E+ R+ +++
Sbjct: 886 ELEVQRQKELMRQRQQQQ 903
Score = 37.4 bits (85), Expect = 0.005
Identities = 29/90 (32%), Positives = 47/90 (52%), Gaps = 6/90 (6%)
Query: 68 RREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDE---KRKEKWKHARVKEREHERRKR 124
RRE M + EE++ + + +E++ R+ E KR+E+ + AR K+ E RR+R
Sbjct: 741 RREAEMRAKREEEERK--RQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQR 798
Query: 125 HRE-EQDKARREWERQKRREMAREHSRRER 153
+E + R E ERQ++ E R R R
Sbjct: 799 EQEIALRRQREEEERQQQEEALRRLEERRR 828
Score = 35.8 bits (81), Expect = 0.015
Identities = 30/133 (22%), Positives = 61/133 (45%), Gaps = 15/133 (11%)
Query: 17 LQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDR 76
L++ K K ++E+ E + ++ + KR ELR EI RR+ E +
Sbjct: 729 LEKAKAAKLEQERREAEMRAKREEEERKRQE----ELRRQQEEIL------RRQQEEERK 778
Query: 77 GEEDDSLAIKPPQQMSWKEKVHH---RKDEKRKEKWKHARVKEREHERRKRHREEQDKAR 133
E++ LA + ++ +++ R+ + +E+ + R ERR+ EE+ + +
Sbjct: 779 RREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRRE--EEERRKQ 836
Query: 134 REWERQKRREMAR 146
E R++ E A+
Sbjct: 837 EELLRKQEEEAAK 849
Score = 35.8 bits (81), Expect = 0.015
Identities = 33/167 (19%), Positives = 76/167 (45%), Gaps = 27/167 (16%)
Query: 10 VKTLDEILQEKKRRKEQEE---KAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSP 66
++ L+E +E++ R++QEE K E + K + + + + LEE LR +R+
Sbjct: 820 LRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEE 879
Query: 67 ----------YRREDSMEDRGEEDDSLA-------------IKPPQQMSWKEKVHHRKDE 103
R+++ M R ++ ++L +K P +W ++ + +
Sbjct: 880 EERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQ 939
Query: 104 KRKEKWKHARVKEREHERRKRHREEQDKARREWERQKRREMAREHSR 150
+ A +++ E ER ++ REEQ + +RE + +++ ++ +
Sbjct: 940 SQATL-SLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQK 985
Score = 33.5 bits (75), Expect = 0.073
Identities = 19/67 (28%), Positives = 40/67 (59%), Gaps = 2/67 (2%)
Query: 89 QQMSWKEKVHHRK-DEKRKEKWKHARVKEREHERRKRHREEQDKA-RREWERQKRREMAR 146
+Q+ EK K +++R+E A+ +E E +R++ R +Q++ RR+ E +++R
Sbjct: 724 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 783
Query: 147 EHSRRER 153
E +RR++
Sbjct: 784 ELARRKQ 790
Score = 32.3 bits (72), Expect = 0.16
Identities = 17/80 (21%), Positives = 40/80 (50%)
Query: 73 MEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKA 132
+E E + A + ++ +E++ +++E + + + R + E E +R +EE +
Sbjct: 737 LEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRR 796
Query: 133 RREWERQKRREMAREHSRRE 152
+RE E RR+ E +++
Sbjct: 797 QREQEIALRRQREEEERQQQ 816
>gi|239747174 PREDICTED: hypothetical protein XP_002343931, partial
[Homo sapiens]
Length = 213
Score = 51.6 bits (122), Expect = 3e-07
Identities = 50/164 (30%), Positives = 76/164 (46%), Gaps = 21/164 (12%)
Query: 4 EKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIR 63
E+D K ++ E+ R++++E E R DR+ ++ + EGE + R
Sbjct: 30 ERDRAKESKTEDRHSERDRQRDRERNRERDR-----DREREKQTDREGERQRERERDRDR 84
Query: 64 NSPYRREDSME---DRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHA-------R 113
RE E DR E D K Q+ E+V R+ EK+KE + R
Sbjct: 85 QRETERERDKERETDRHTETDRERQK--QKEREMERVRDREREKQKEMGRERQTDRETDR 142
Query: 114 VKEREHERRK---RHREEQDKAR-REWERQKRREMAREHSRRER 153
+ER+ ER + R R+ +D+ R RE ER++ RE RE RER
Sbjct: 143 ERERQAERERETGRERKTEDRHRERERERKRERERKRETKERER 186
Score = 46.2 bits (108), Expect = 1e-05
Identities = 34/140 (24%), Positives = 70/140 (50%), Gaps = 20/140 (14%)
Query: 9 KVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYR 68
+ +T+D ++++RR+E + + + + ++DR S+RD + E R+
Sbjct: 13 ETETMD---RQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRE------RDRDRE 63
Query: 69 REDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHA-RVKEREHERRKRHRE 127
RE + GE Q+ +++ R+ E+ ++K + R E + ER+K+
Sbjct: 64 REKQTDREGER---------QRERERDRDRQRETERERDKERETDRHTETDRERQKQKER 114
Query: 128 EQDKARREWERQKRREMARE 147
E ++ R + ER+K++EM RE
Sbjct: 115 EMERVR-DREREKQKEMGRE 133
Score = 45.1 bits (105), Expect = 2e-05
Identities = 33/138 (23%), Positives = 67/138 (48%), Gaps = 6/138 (4%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSD---DRDSKRDSLEEGELRDHCMEITIRNSPYRRE-DSM 73
++++R K+ + + E +R + D R+++R+ +E E H R RE + +
Sbjct: 60 RDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERV 119
Query: 74 EDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRHRE-EQDKA 132
DR E + Q ++ R+ E+ +E + + ++R H R+R R+ E+++
Sbjct: 120 RDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDR-HRERERERKRERERK 178
Query: 133 RREWERQKRREMAREHSR 150
R ER++ +M RE R
Sbjct: 179 RETKERERHTDMERERQR 196
Score = 45.1 bits (105), Expect = 2e-05
Identities = 30/133 (22%), Positives = 62/133 (46%), Gaps = 4/133 (3%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRG 77
++++ +E++++ E R +D K+ E +RD E R+ D DR
Sbjct: 84 RQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRE 143
Query: 78 EEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKARREWE 137
E + + + E H ++ +RK + R ++RE + R+RH + + + +RE +
Sbjct: 144 RERQAERERETGRERKTEDRHRERERERKRE----RERKRETKERERHTDMERERQRETD 199
Query: 138 RQKRREMAREHSR 150
R++ R+ E R
Sbjct: 200 RKRDRQRESERER 212
Score = 34.3 bits (77), Expect = 0.043
Identities = 23/64 (35%), Positives = 32/64 (50%), Gaps = 10/64 (15%)
Query: 100 RKDEKRKEKWKHARVKEREHER-------RKRHREEQDKARREWERQKRREMAREHSR-- 150
R+ ++ KE R ER+ +R R R RE + + RE ERQ+ RE R+ R
Sbjct: 29 RERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERERDRDRQRET 88
Query: 151 -RER 153
RER
Sbjct: 89 ERER 92
Score = 30.4 bits (67), Expect = 0.62
Identities = 28/121 (23%), Positives = 49/121 (40%), Gaps = 16/121 (13%)
Query: 46 DSLEEGELRDHCMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKR 105
+S EG E R RRE E ++ + ++ +++ +R+ ++
Sbjct: 2 ESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRD 61
Query: 106 KEKWKHARVKEREHERRKRHRE-------EQDKAR---------REWERQKRREMAREHS 149
+E+ K + R+R R+ E+DK R RE ++QK REM R
Sbjct: 62 REREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRD 121
Query: 150 R 150
R
Sbjct: 122 R 122
Score = 27.3 bits (59), Expect = 5.2
Identities = 14/48 (29%), Positives = 23/48 (47%), Gaps = 3/48 (6%)
Query: 106 KEKWKHARVKEREHERRKRHREEQDKARREWERQKRREMAREHSRRER 153
K + +H + +R++ R E D RE +R K + HS R+R
Sbjct: 4 KTEGRHTHTETETMDRQRERRRETD---RERDRAKESKTEDRHSERDR 48
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 50.8 bits (120), Expect = 4e-07
Identities = 31/138 (22%), Positives = 77/138 (55%), Gaps = 9/138 (6%)
Query: 4 EKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIR 63
E+ W+ + ++I +++++R+EQEEK K + + + ++E E + E IR
Sbjct: 583 EEKVWRQE--EKIREQEEKRQEQEEKM----WKQEEKIREQEEKIQEQEEKIREQEEKIR 636
Query: 64 NSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRK 123
++ E GE+++ + + ++M +E+ R++EK +E+ K +++E+E + R+
Sbjct: 637 EQEEMTQEQEEKMGEQEEKMC-EQEEKMQEQEETMWRQEEKIREQEK--KIREQEEKIRE 693
Query: 124 RHREEQDKARREWERQKR 141
+ Q++ + WE++++
Sbjct: 694 QEEMMQEQEEKMWEQEEK 711
Score = 48.1 bits (113), Expect = 3e-06
Identities = 33/139 (23%), Positives = 74/139 (53%), Gaps = 15/139 (10%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRG 77
QEKK +++E+ E ++++ + R + + + E EI +R+++ M ++
Sbjct: 449 QEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEI------WRQKEKMHEQE 502
Query: 78 EEDDSLAIKPPQQMSWK--EKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKARRE 135
E+ I+ ++ W+ EK+ ++++ R+++ K R +E+ E+ + REE+ +E
Sbjct: 503 EK-----IRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQE 557
Query: 136 --WERQKRREMAREHSRRE 152
WE +KR+E + R+E
Sbjct: 558 KIWEEEKRQEQEDKMWRQE 576
Score = 46.2 bits (108), Expect = 1e-05
Identities = 32/145 (22%), Positives = 79/145 (54%), Gaps = 16/145 (11%)
Query: 4 EKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIR 63
EK W+ +E + E+++ +E+E++ E + + +++ +++ + + + H E IR
Sbjct: 450 EKKMWRQ---EEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIR 506
Query: 64 NSP---YRREDSMEDRGEEDDSLAIKPPQQMSWK--EKVHHRKDEKRKEKWKHARVKERE 118
+R+E+ + ++ E+ I+ ++ W+ EK+ +++ R+E+ H + K E
Sbjct: 507 KQEEKVWRQEEKIREQEEK-----IREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWE 561
Query: 119 HERRKRHREEQDKARREWERQKRRE 143
E+R +E++DK R+ E+ + +E
Sbjct: 562 EEKR---QEQEDKMWRQEEKIREQE 583
Score = 45.4 bits (106), Expect = 2e-05
Identities = 35/159 (22%), Positives = 80/159 (50%), Gaps = 18/159 (11%)
Query: 3 DEKDSW----KVKTLDEILQEKKRRKEQEEKA---EIKRLKNSDDRDSKRDSLEEGELRD 55
++++ W K+ +EI ++K++ EQEEK E K + + + + + E E +
Sbjct: 474 EQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKM 533
Query: 56 HCMEITIRNSP--YRREDSM---------EDRGEEDDSLAIKPPQQMSWKEKVHHRKDEK 104
E IR +R E+ M E R E++D + + + +EKV ++++
Sbjct: 534 WRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKI 593
Query: 105 RKEKWKHARVKEREHERRKRHREEQDKARREWERQKRRE 143
R+++ K +E+ ++ ++ RE+++K + + E+ + +E
Sbjct: 594 REQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQE 632
Score = 45.1 bits (105), Expect = 2e-05
Identities = 35/146 (23%), Positives = 73/146 (50%), Gaps = 15/146 (10%)
Query: 9 KVKTLDEILQEKKRRKEQEEKA----EIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRN 64
K++ +E++ EK+ + ++E+ E K + + K + + E E + H E
Sbjct: 350 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQE----- 404
Query: 65 SPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKR 124
+ + E R EE+ I+ ++ +E R++EK +E+ + R +E++ R++
Sbjct: 405 ---KIREQEEKRQEEEK---IREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEE 458
Query: 125 HREEQDKARREWERQKRREMAREHSR 150
EQ+K R E +RQ++ EM R+ +
Sbjct: 459 KIHEQEKIREEEKRQEQEEMWRQEEK 484
Score = 44.7 bits (104), Expect = 3e-05
Identities = 34/152 (22%), Positives = 78/152 (51%), Gaps = 30/152 (19%)
Query: 4 EKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIR 63
E+ W+ + L+EK +E+ + E KR + R+ ++ +E ++
Sbjct: 383 EEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKM---------- 432
Query: 64 NSPYRREDSMEDRGEEDDSLAIKPPQQMSWK--EKVHH----RKDEKRKEKWKHARVKER 117
+R+E+ + ++ E+ I+ ++ W+ EK+H R++EKR+E+ + R +E+
Sbjct: 433 ---WRQEEKIREQEEK-----IREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEK 484
Query: 118 EHE------RRKRHREEQDKARREWERQKRRE 143
HE ++++ E+++K R++ E+ R+E
Sbjct: 485 IHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQE 516
Score = 42.7 bits (99), Expect = 1e-04
Identities = 32/158 (20%), Positives = 75/158 (47%), Gaps = 7/158 (4%)
Query: 1 MGDEKDSWKVKTLDEILQEK--KRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCM 58
+G E S K ++ + + R +Q+E+ ++ + + + K EE ++R+
Sbjct: 270 LGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEE-KIREQEE 328
Query: 59 EITIRNSPYRREDSM----EDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARV 114
+I + RR++ M E++ + + + ++M +E++ K+EK + + +
Sbjct: 329 KIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWE 388
Query: 115 KEREHERRKRHREEQDKARREWERQKRREMAREHSRRE 152
KE + + EQ+K R + E+++ E RE +R+
Sbjct: 389 KEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQ 426
Score = 40.8 bits (94), Expect = 5e-04
Identities = 40/159 (25%), Positives = 78/159 (49%), Gaps = 17/159 (10%)
Query: 3 DEKDSWKVKTLDEILQEKKRRKEQ-----EEKAEIKRLKNSDDRDSKRDSLEEGELRDHC 57
+E + W L++ +EK R+E+ EEK + + K + + R+ E+ ++
Sbjct: 286 EENELWN--RLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEM 343
Query: 58 MEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSW-KEKVHHRKDEKRKEKWKHAR-VK 115
M + RR++ M EE ++ ++M W KE+ R++E EK + R ++
Sbjct: 344 M--WEKEEKMRRQEEMMWEKEEK----MRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELE 397
Query: 116 EREHERRKRHREEQDKARRE--WERQKRREMAREHSRRE 152
E+ HE+ K +E+ + E E++KR+E + R+E
Sbjct: 398 EKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 436
Score = 40.4 bits (93), Expect = 6e-04
Identities = 33/163 (20%), Positives = 82/163 (50%), Gaps = 42/163 (25%)
Query: 9 KVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYR 68
K++ L+E + E+++ +EQEEK + +++ +++ +E E + +R
Sbjct: 392 KIRELEEKMHEQEKIREQEEK------RQEEEKIREQEKRQEQEAK-----------MWR 434
Query: 69 REDSMEDRGEEDDSLAIKPPQQMSWK-EKVHHRKDEKRKEK--------WKHA------- 112
+E+ + ++ E+ I+ ++ W+ E+ H +++ R+E+ W+
Sbjct: 435 QEEKIREQEEK-----IREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQE 489
Query: 113 ---RVKEREHERRKRHREEQDKARREWER-QKRREMAREHSRR 151
R KE+ HE+ ++ R++++K R+ E+ +++ E RE +
Sbjct: 490 EIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEK 532
Score = 39.7 bits (91), Expect = 0.001
Identities = 30/160 (18%), Positives = 79/160 (49%), Gaps = 18/160 (11%)
Query: 4 EKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSL---EEGELRDHCMEI 60
E+ W+ + + +EK + +E++ + + ++++ +++ +++ + +E ++R +
Sbjct: 299 EEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMM 358
Query: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSWK---------EKVHHRKDEKRKEKWKH 111
+ RR++ M EE ++ ++M W+ EK+H ++ + +E+ +
Sbjct: 359 WEKEEKMRRQEEMMWEKEEK----MRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQ 414
Query: 112 ARVKEREHERRKRHREEQDKARREWERQKRREMAREHSRR 151
K RE E KR +E R+E + +++ E RE ++
Sbjct: 415 EEEKIREQE--KRQEQEAKMWRQEEKIREQEEKIREQEKK 452
Score = 37.7 bits (86), Expect = 0.004
Identities = 27/139 (19%), Positives = 72/139 (51%), Gaps = 5/139 (3%)
Query: 14 DEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSM 73
D++ +++++ +EQEEK ++ + +++ KR EE + E IR + ++
Sbjct: 570 DKMWRQEEKIREQEEKVW-RQEEKIREQEEKRQEQEEKMWKQ---EEKIREQEEKIQEQE 625
Query: 74 EDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKAR 133
E E+++ + + +EK+ ++++ +++ K +E + ++ RE++ K R
Sbjct: 626 EKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIR 685
Query: 134 REWER-QKRREMAREHSRR 151
+ E+ +++ EM +E +
Sbjct: 686 EQEEKIREQEEMMQEQEEK 704
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 50.8 bits (120), Expect = 4e-07
Identities = 32/131 (24%), Positives = 73/131 (55%), Gaps = 8/131 (6%)
Query: 14 DEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSM 73
+E+ ++++ +EQ+ + E++R + +R +R+ LE L +E +E
Sbjct: 138 EELEIQRRQLQEQQRQKELERERLERER-MERERLERERLERERLE----RERLEQEQLE 192
Query: 74 EDRGEEDDSLAIKPPQQMSWKEKV--HHRKDEKRKEKWKHARVKEREHERRKRHREEQ-D 130
+R E + ++ +++ +E++ R D +R+E+ + R++ E ER++R R+EQ +
Sbjct: 193 RERQERERQERLERQERLERQERLERQERLDRERQERQERERLERLERERQERERQEQLE 252
Query: 131 KARREWERQKR 141
+ + EWER++R
Sbjct: 253 REQLEWERERR 263
Score = 37.0 bits (84), Expect = 0.007
Identities = 21/92 (22%), Positives = 45/92 (48%), Gaps = 7/92 (7%)
Query: 62 IRNSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHER 121
++N P + E ++ R ++ Q+ E+ ++ +E+ + R++ ER
Sbjct: 131 VQNGPSQEELEIQRR-------QLQEQQRQKELERERLERERMERERLERERLERERLER 183
Query: 122 RKRHREEQDKARREWERQKRREMAREHSRRER 153
+ +E+ ++ R+E ERQ+R E R+ER
Sbjct: 184 ERLEQEQLERERQERERQERLERQERLERQER 215
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 50.8 bits (120), Expect = 4e-07
Identities = 32/131 (24%), Positives = 73/131 (55%), Gaps = 8/131 (6%)
Query: 14 DEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSM 73
+E+ ++++ +EQ+ + E++R + +R +R+ LE L +E +E
Sbjct: 138 EELEIQRRQLQEQQRQKELERERLERER-MERERLERERLERERLE----RERLEQEQLE 192
Query: 74 EDRGEEDDSLAIKPPQQMSWKEKV--HHRKDEKRKEKWKHARVKEREHERRKRHREEQ-D 130
+R E + ++ +++ +E++ R D +R+E+ + R++ E ER++R R+EQ +
Sbjct: 193 RERQERERQERLERQERLERQERLERQERLDRERQERQERERLERLERERQERERQEQLE 252
Query: 131 KARREWERQKR 141
+ + EWER++R
Sbjct: 253 REQLEWERERR 263
Score = 37.0 bits (84), Expect = 0.007
Identities = 21/92 (22%), Positives = 45/92 (48%), Gaps = 7/92 (7%)
Query: 62 IRNSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHER 121
++N P + E ++ R ++ Q+ E+ ++ +E+ + R++ ER
Sbjct: 131 VQNGPSQEELEIQRR-------QLQEQQRQKELERERLERERMERERLERERLERERLER 183
Query: 122 RKRHREEQDKARREWERQKRREMAREHSRRER 153
+ +E+ ++ R+E ERQ+R E R+ER
Sbjct: 184 ERLEQEQLERERQERERQERLERQERLERQER 215
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 50.4 bits (119), Expect = 6e-07
Identities = 42/159 (26%), Positives = 77/159 (48%), Gaps = 15/159 (9%)
Query: 9 KVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEE---GELRDHCMEITIRNS 65
+++ ++ L+E+K +EQEE+ + + K + + R+ E+ E R E +R
Sbjct: 329 ELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQ 388
Query: 66 PYRREDSMEDRGEEDDSLAIKPP----QQMSWKEKVHHRKDEKRKEKWKHAR-------V 114
+ D E E+D+ L K Q+ W++ R+++K +E+ K R
Sbjct: 389 EQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQE 448
Query: 115 KEREHERRKRHREEQDKARREWER-QKRREMAREHSRRE 152
+ER ER K+ REE++ R + E+ QK+ E E +E
Sbjct: 449 EERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKE 487
Score = 48.1 bits (113), Expect = 3e-06
Identities = 34/167 (20%), Positives = 84/167 (50%), Gaps = 17/167 (10%)
Query: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDR-DSKRDSLEEGELRDHCME 59
M D+++ + KT + QEKK ++E+ E +R++ + + + + + E E + E
Sbjct: 560 MWDQEERMEKKTQE---QEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQE 616
Query: 60 ITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKV--HHRKDEKRKEKWKHARVKER 117
++ + + E E+++ + + + +EK+ R E++++ W+H +++E+
Sbjct: 617 EKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQ 676
Query: 118 EH---------ERRKRHREEQDKARREWERQKRR--EMAREHSRRER 153
E E+ K ++ Q++ ++ W+++K R E RE ++ R
Sbjct: 677 EKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMR 723
Score = 45.8 bits (107), Expect = 1e-05
Identities = 27/141 (19%), Positives = 67/141 (47%), Gaps = 2/141 (1%)
Query: 14 DEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSM 73
+E +QE++ + +++E+ ++ + +++ K EE + P ++E
Sbjct: 609 EEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLW 668
Query: 74 EDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKERE--HERRKRHREEQDK 131
E ++ + +++ +EK+ + E+ K+ W +++E E ER K+ REE++
Sbjct: 669 EHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEM 728
Query: 132 ARREWERQKRREMAREHSRRE 152
R + E+ + +E + E
Sbjct: 729 MREQEEKMQEQEEKMQEQEEE 749
Score = 44.7 bits (104), Expect = 3e-05
Identities = 35/158 (22%), Positives = 81/158 (51%), Gaps = 15/158 (9%)
Query: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
M +E+++ + + QE+ +++E++ + +RL ++ +++ ++E E + E
Sbjct: 459 MREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEE 518
Query: 61 TIRNSP--YRREDSM---EDRGEEDDSL-----AIKPPQQMSW--KEKVHHRKDEKRKEK 108
IR+ + +E M E E++D + ++ +Q W +E++ + E+ K+
Sbjct: 519 KIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKT 578
Query: 109 W---KHARVKEREHERRKRHREEQDKARREWERQKRRE 143
W + R +ER ER K+ REE++ R + E+ + +E
Sbjct: 579 WDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQE 616
Score = 43.5 bits (101), Expect = 7e-05
Identities = 23/156 (14%), Positives = 75/156 (48%), Gaps = 21/156 (13%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRG 77
Q +K R+E++ + + K+ ++ +++ + + + E E + E T+R + + E+
Sbjct: 422 QVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMW 481
Query: 78 EEDDS----LAIKPPQQMSWKEKVHHRKDEK-----------------RKEKWKHARVKE 116
E+++ + ++ W+++ ++EK K+ W+ +++E
Sbjct: 482 EQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMRE 541
Query: 117 REHERRKRHREEQDKARREWERQKRREMAREHSRRE 152
+E + ++ + +D+ ++ W++++R E + ++
Sbjct: 542 QEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKK 577
Score = 43.1 bits (100), Expect = 9e-05
Identities = 41/172 (23%), Positives = 86/172 (50%), Gaps = 25/172 (14%)
Query: 4 EKDSWKVKTLDEILQEKKRRKEQEEKA--EIKRLKNSDD--RDSKRDSLEEGELRDHCME 59
E+ W+ + + + +++ + +EQEEK + KRL+ + R+ +++ E+ ELR+ +
Sbjct: 292 EEKMWRQE--ERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQ 349
Query: 60 ITIRNSP-YRREDSMEDRGE----------EDDSLAIKPPQQMSWKEKVHHRKDEKRKEK 108
+ + + +E+ M ++ E E + + Q+M +E+ +DE+ +EK
Sbjct: 350 MQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREK 409
Query: 109 WKHARVKEREHERRKRHREE-----QDKARREWERQKRRE---MAREHSRRE 152
+ R +E+ E+ ++ REE Q+K R+ E + + E RE RE
Sbjct: 410 EERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMRE 461
Score = 43.1 bits (100), Expect = 9e-05
Identities = 30/137 (21%), Positives = 71/137 (51%), Gaps = 21/137 (15%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSL--EEGELRDHCMEITIRNSPYRREDSMED 75
QE+K R ++E + K++ + + D + +E ++RD ++ + +E+ ME
Sbjct: 516 QEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKM------WDQEERMEK 569
Query: 76 RGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKE---REHERRKRHREE--QD 130
+ +E + + +W ++ R++E+ +E+ K R +E RE E + + +EE Q+
Sbjct: 570 KTQEQE--------KKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQE 621
Query: 131 KARREWERQKRREMARE 147
+ + WE++++ + E
Sbjct: 622 QEEKMWEQEEKMQEQEE 638
Score = 42.0 bits (97), Expect = 2e-04
Identities = 33/154 (21%), Positives = 74/154 (48%), Gaps = 24/154 (15%)
Query: 15 EILQEKKRRKEQEEKA--EIKRLKNSDDRDSK---------RDSLEEGELRDHCMEITIR 63
E +QE+++ +EQEEK + K K + +++ K +S+ E E + E +R
Sbjct: 671 EKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMR 730
Query: 64 NSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKV--HHRKDEKRKEKWKHARVKE----- 116
+ ++ E E+++ + + + +EK+ R E++++ W+H +++E
Sbjct: 731 EQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIW 790
Query: 117 ------REHERRKRHREEQDKARREWERQKRREM 144
R+ E + R +EE+ + + E R + +M
Sbjct: 791 EQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKM 824
Score = 41.6 bits (96), Expect = 3e-04
Identities = 32/146 (21%), Positives = 71/146 (48%), Gaps = 23/146 (15%)
Query: 14 DEILQEKKRRKEQEEKA--------EIKRLKNSDD--RDSKRDSLEEGELRDHCMEITIR 63
DE L+EK+ R ++EK E K+++ + RD + EE +R+ ++
Sbjct: 403 DERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREE 462
Query: 64 NSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREH---- 119
R ++ + EE+ + ++ W+++ R E++++ W+ +++E+E
Sbjct: 463 EETMREQEEKMQKQEEN----MWEQEEKEWQQQ---RLPEQKEKLWEQEKMQEQEEKIWE 515
Query: 120 -ERRKRHREEQ-DKARREWERQKRRE 143
E + R +EE + ++ W ++K RE
Sbjct: 516 QEEKIRDQEEMWGQEKKMWRQEKMRE 541
Score = 40.4 bits (93), Expect = 6e-04
Identities = 31/151 (20%), Positives = 76/151 (50%), Gaps = 14/151 (9%)
Query: 4 EKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDS-LEEGELRDHCMEITI 62
E+ W+ + + + +++K+ +EQE+K +++ ++R ++D L E E R E
Sbjct: 368 EEKMWRQE--ERLWEQEKQMREQEQK-----MRDQEERMWEQDERLREKEERMREQEKMW 420
Query: 63 RNSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERR 122
RE E + +E + ++M +E++ R+ + R+E+ ++E+E + +
Sbjct: 421 EQVEKMRE---EKKMQEQEKKTRDQEEKMQEEERIREREKKMREEE---ETMREQEEKMQ 474
Query: 123 KRHREEQDKARREWERQKRREMAREHSRRER 153
K+ ++ +EW++Q+ E + +E+
Sbjct: 475 KQEENMWEQEEKEWQQQRLPEQKEKLWEQEK 505
Score = 38.9 bits (89), Expect = 0.002
Identities = 27/153 (17%), Positives = 73/153 (47%), Gaps = 11/153 (7%)
Query: 4 EKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIR 63
E+ W+ + L E +K++ E E+ E ++++ +++ +++ +E+ + T
Sbjct: 651 EEKMWEQQRLPE---QKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQE--KKTWD 705
Query: 64 NSPYRREDSMEDRGE---EDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHE 120
R E+SM +R + E++ + + ++M +E+ + E+ +E W+ + E
Sbjct: 706 QEKMREEESMREREKKMREEEEMMREQEEKMQEQEE---KMQEQEEEMWEQEEKMWEQEE 762
Query: 121 RRKRHREEQDKARREWERQKRREMAREHSRRER 153
+ + ++ + WE +K +E + + E+
Sbjct: 763 KMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEK 795
Score = 36.6 bits (83), Expect = 0.009
Identities = 32/145 (22%), Positives = 70/145 (48%), Gaps = 8/145 (5%)
Query: 4 EKDSW----KVKTLDEILQEKKRRKEQEEKA-EIKRLKNSDDRDSKRDSLEEGELRDHCM 58
E++ W K+ +E + E++R EQ+EK E ++++ + + + + + E +
Sbjct: 747 EEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQ 806
Query: 59 EITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKERE 118
E +R + E +++ + + + +EK+ + +EK +EK + K RE
Sbjct: 807 EEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQ-EEKMEEKMQGQEEKMRE 865
Query: 119 HERRKRHREEQDKARREWERQKRRE 143
E + R +EE K R + E+ + +E
Sbjct: 866 QEEKMRGQEE--KMREQEEKMRGQE 888
Score = 36.2 bits (82), Expect = 0.011
Identities = 26/137 (18%), Positives = 67/137 (48%), Gaps = 4/137 (2%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRG 77
QE+K +++E+ E +RL ++ + + ++E E E I + + E
Sbjct: 643 QEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQE-QEEKIWEQEKMEKKTQEQEK 701
Query: 78 EEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKARREWE 137
+ D ++ + M +EK ++E +E+ +++E+E + +++ E ++ + WE
Sbjct: 702 KTWDQEKMREEESMREREKKMREEEEMMREQ--EEKMQEQEEKMQEQEEEMWEQEEKMWE 759
Query: 138 RQKRR-EMAREHSRRER 153
++++ E R ++E+
Sbjct: 760 QEEKMWEQQRLPEQKEK 776
Score = 35.8 bits (81), Expect = 0.015
Identities = 22/68 (32%), Positives = 40/68 (58%), Gaps = 6/68 (8%)
Query: 89 QQMSWKEKVHHRKDEK--RKEKWKHARVKEREHERRKRHREEQDKARREWERQKR-REMA 145
Q+ W+++ R+ EK RK++ K R +ER E+ + RE+++K W ++KR RE
Sbjct: 271 QEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKM---WRQEKRLREQE 327
Query: 146 REHSRRER 153
+E +E+
Sbjct: 328 KELREQEK 335
Score = 33.5 bits (75), Expect = 0.073
Identities = 36/157 (22%), Positives = 74/157 (47%), Gaps = 16/157 (10%)
Query: 9 KVKTLDEILQEKKRRKEQEE---KAEIKRLKNSDDRDS------KRDSLEEGELRDHCME 59
++K + LQEK E E+ + +K LK +R + ++L+E R E
Sbjct: 222 ELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQE-EE 280
Query: 60 ITIRNSPYRREDSMEDRGEE---DDSLAIKPPQQMSWKEKVHHRKDEKR-KEKWKHARVK 115
+ + R+++ R EE + ++ ++ W+++ R+ EK +E+ K R +
Sbjct: 281 LREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQ 340
Query: 116 E--REHERRKRHREEQDKARREWERQKRREMAREHSR 150
+ RE E + + +EE+ + E R++ +M R+ R
Sbjct: 341 KELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEER 377
Score = 33.5 bits (75), Expect = 0.073
Identities = 34/157 (21%), Positives = 73/157 (46%), Gaps = 29/157 (18%)
Query: 20 KKRRKEQEEKAEIKRLKNSDD----RDSKRDSLEEGELRDHCMEITIRNSPYRREDSMED 75
KK+ E +EK + + S+ ++ KR L T++ +R+E+ + +
Sbjct: 224 KKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELRE 283
Query: 76 RGEEDDSLAIKPPQQMSWKEKVHHRKDE-----KRKEKWKHA-RVKEREHERRK------ 123
+ ++ I+ ++ W+++ R+ E + ++ W+ R++E+E E R+
Sbjct: 284 QEKK-----IRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELR 338
Query: 124 -----RHREEQDKARRE--WER-QKRREMAREHSRRE 152
R +EEQ + + E WE+ +K RE + R+E
Sbjct: 339 EQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQE 375
Score = 30.0 bits (66), Expect = 0.81
Identities = 29/146 (19%), Positives = 72/146 (49%), Gaps = 12/146 (8%)
Query: 14 DEILQEKKRRKEQEEKA-EIKRLKNSDDRDSKRDSLEEGE--------LRDHCMEITIRN 64
+E+ +++++ EQEEK E +RL ++ + + ++E E +RD ++ +
Sbjct: 748 EEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQE 807
Query: 65 SPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKR 124
R ++ + RG+E+ + ++M +E+ ++EK + + K + E + R
Sbjct: 808 EKMRGQEE-KMRGQEEKMWGQE--EKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMR 864
Query: 125 HREEQDKARREWERQKRREMAREHSR 150
+EE+ + + E R++ +M + +
Sbjct: 865 EQEEKMRGQEEKMREQEEKMRGQEEK 890
Score = 29.3 bits (64), Expect = 1.4
Identities = 26/121 (21%), Positives = 58/121 (47%), Gaps = 12/121 (9%)
Query: 9 KVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYR 68
K++ ++I +++++ ++QEEK + K + R E+ ++ M +
Sbjct: 782 KMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKM--------WG 833
Query: 69 REDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREE 128
+E+ M + E+ K ++M +E+ K +++EK + K RE E + R +EE
Sbjct: 834 QEEKMWGQEEKMWGQEEKMEEKMQGQEE----KMREQEEKMRGQEEKMREQEEKMRGQEE 889
Query: 129 Q 129
+
Sbjct: 890 K 890
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 50.4 bits (119), Expect = 6e-07
Identities = 32/148 (21%), Positives = 76/148 (51%), Gaps = 7/148 (4%)
Query: 3 DEKDSW----KVKTLDEILQEKKRRKEQEEKA---EIKRLKNSDDRDSKRDSLEEGELRD 55
++++ W K++ +EI ++K++ EQEEK E K + + + + + E E +
Sbjct: 521 EQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKV 580
Query: 56 HCMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVK 115
E IR + + E E+++ + + +EK+ ++++ ++++ K R +
Sbjct: 581 WRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQE 640
Query: 116 EREHERRKRHREEQDKARREWERQKRRE 143
E+ E+ K+ RE+++K R + E + +E
Sbjct: 641 EKIREQEKKIREQEEKIREQEEMMQEQE 668
Score = 48.1 bits (113), Expect = 3e-06
Identities = 32/149 (21%), Positives = 82/149 (55%), Gaps = 15/149 (10%)
Query: 3 DEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLE-----EGELRDHC 57
++++ W+ K ++I +++++ ++QEEK + K D + R+ E E ++R+
Sbjct: 534 EQEEIWRQK--EKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQE 591
Query: 58 MEITIRNSPYRREDSM-----EDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHA 112
+I + R ++ M E GE+++ + + + +EK+ R++EK +E+ K
Sbjct: 592 EKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMR-RQEEKIREQEK-- 648
Query: 113 RVKEREHERRKRHREEQDKARREWERQKR 141
+++E+E + R++ Q++ + WE++++
Sbjct: 649 KIREQEEKIREQEEMMQEQEEKMWEQEEK 677
Score = 47.8 bits (112), Expect = 4e-06
Identities = 38/173 (21%), Positives = 88/173 (50%), Gaps = 23/173 (13%)
Query: 4 EKDSWKVKTLDEILQEKKR-----RKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCM 58
E+ W+ + L+EK R+++E++ E ++++ + R + + E +
Sbjct: 430 EEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ 489
Query: 59 EITIRNSP---YRREDSM--------EDRGEEDDSLAIKP----PQQMSW--KEKVHHRK 101
E IR +R+E+ + E++ +E + + + Q+ W KEK+H ++
Sbjct: 490 EEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQE 549
Query: 102 DEKRKEKWKHARVKEREHERRKRHREEQDKARREWER-QKRREMAREHSRRER 153
++ RK++ K R +E+ H++ ++ RE+++K R+ E+ +++ E RE + R
Sbjct: 550 EKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIR 602
Score = 45.4 bits (106), Expect = 2e-05
Identities = 33/149 (22%), Positives = 76/149 (51%), Gaps = 7/149 (4%)
Query: 9 KVKTLDEILQEKKRRKEQEEKA----EIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRN 64
K++ +E++ EK+ + ++E+ E K + + K + + E E + H E IR
Sbjct: 397 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQE-KIRE 455
Query: 65 SPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKR 124
+R++ E++ E + + + +EK+ ++++ R+++ K R +E+ HE+ K
Sbjct: 456 QEEKRQE--EEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKI 513
Query: 125 HREEQDKARREWERQKRREMAREHSRRER 153
EE+ + + E RQ+ + +E R++
Sbjct: 514 REEEKRQEQEEMWRQEEKIREQEEIWRQK 542
Score = 40.4 bits (93), Expect = 6e-04
Identities = 38/158 (24%), Positives = 78/158 (49%), Gaps = 11/158 (6%)
Query: 1 MGDEKDSWKVKTLDEILQEK--KRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCM 58
+G E S K ++ + + R +Q+E+ ++ + + + K EE ++R+
Sbjct: 331 LGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEE-KIREQEE 389
Query: 59 EITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSW-KEKVHHRKDEKRKEKWKHAR-VKE 116
+I + RR++ M EE ++ ++M W KE+ R++E EK + R ++E
Sbjct: 390 KIREQEEKMRRQEEMMWEKEEK----MRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEE 445
Query: 117 REHERRKRHREEQDKARRE--WERQKRREMAREHSRRE 152
+ HE+ K +E+ + E E++KR+E + R+E
Sbjct: 446 KMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 483
Score = 37.4 bits (85), Expect = 0.005
Identities = 27/133 (20%), Positives = 69/133 (51%), Gaps = 6/133 (4%)
Query: 9 KVKTLDEILQEKKRR-KEQEEKAEIKRLKNSDDRDS---KRDSLEEGELRDHCMEITIRN 64
K++ +E ++E++ + +EQEE + + K + + + + ++E E + E IR
Sbjct: 586 KIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIRE 645
Query: 65 SPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKER--EHERR 122
+ + E E+++ + + + +EK+ ++++ ++++ K R +E+ E E R
Sbjct: 646 QEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVR 705
Query: 123 KRHREEQDKARRE 135
R +EE+ + +E
Sbjct: 706 LRQQEEKMQEHQE 718
Score = 37.4 bits (85), Expect = 0.005
Identities = 24/123 (19%), Positives = 62/123 (50%), Gaps = 5/123 (4%)
Query: 9 KVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYR 68
K++ +E+ QE++ + ++E+ ++ + +++ K EE ++R+ +I + R
Sbjct: 600 KIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEE-KIREQEKKIREQEEKIR 658
Query: 69 REDSM----EDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKEREHERRKR 124
++ M E++ E + + ++M +E+ R++EK E+ R +E + + +
Sbjct: 659 EQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 718
Query: 125 HRE 127
H E
Sbjct: 719 HLE 721
Score = 37.0 bits (84), Expect = 0.007
Identities = 34/158 (21%), Positives = 76/158 (48%), Gaps = 15/158 (9%)
Query: 3 DEKDSWKVKTLDEILQEKKRRKEQ-----EEKAEIKRLKNSDDRDSKRDSLEEGELRDHC 57
+E + W L++ +EK R+E+ EEK + + K + + R+ E+ ++
Sbjct: 347 EENELWN--RLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEM 404
Query: 58 MEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARVKE- 116
M + RR++ M EE ++ ++M W+++ R+ E++ + + R +E
Sbjct: 405 M--WEKEEKMRRQEEMMWEKEEK----MRRQEEMMWEKEEKIRELEEKMHEQEKIREQEE 458
Query: 117 -REHERRKRHREEQDKARREWERQKRREMAREHSRRER 153
R+ E + R +E++ + + RQ+ + +E RE+
Sbjct: 459 KRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQ 496
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.126 0.360
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,861,306
Number of Sequences: 37866
Number of extensions: 352659
Number of successful extensions: 11717
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 560
Number of HSP's successfully gapped in prelim test: 590
Number of HSP's that attempted gapping in prelim test: 3272
Number of HSP's gapped (non-prelim): 4678
length of query: 153
length of database: 18,247,518
effective HSP length: 93
effective length of query: 60
effective length of database: 14,725,980
effective search space: 883558800
effective search space used: 883558800
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 57 (26.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.