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Search of human proteins with 117306178
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|117306178 hypothetical protein LOC55731 [Homo sapiens]
(562 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|117306178 hypothetical protein LOC55731 [Homo sapiens] 1159 0.0
gi|117306174 hypothetical protein LOC55731 [Homo sapiens] 1159 0.0
gi|14249534 hypothetical protein LOC84915 [Homo sapiens] 152 6e-37
gi|21327715 transcription elongation regulator 1 isoform 1 [Homo... 59 9e-09
gi|91208418 transcription elongation regulator 1 isoform 2 [Homo... 59 2e-08
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 57 6e-08
gi|222352122 hypothetical protein LOC284297 [Homo sapiens] 50 7e-06
gi|148612809 WNK lysine deficient protein kinase 1 [Homo sapiens] 49 9e-06
gi|163965366 nascent polypeptide-associated complex alpha subuni... 46 1e-04
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] 45 2e-04
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 44 4e-04
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] 44 5e-04
gi|157743257 POU domain, class 6, transcription factor 2 [Homo s... 43 7e-04
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 43 9e-04
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 43 9e-04
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 43 9e-04
gi|54112403 chromodomain helicase DNA binding protein 7 [Homo sa... 42 0.001
gi|17864090 autism susceptibility candidate 2 isoform 1 [Homo sa... 42 0.001
gi|91176325 bromodomain adjacent to zinc finger domain, 2A [Homo... 42 0.001
gi|239745032 PREDICTED: hypothetical protein XP_002343336 [Homo ... 42 0.002
gi|83977459 pleckstrin homology-like domain, family A, member 1 ... 42 0.002
gi|55750053 atrophin-1 [Homo sapiens] 41 0.003
gi|55750041 atrophin-1 [Homo sapiens] 41 0.003
gi|83776598 virus-induced signaling adapter [Homo sapiens] 41 0.003
gi|187829452 autism susceptibility candidate 2 isoform 2 [Homo s... 41 0.003
gi|149158696 HLA-B associated transcript-3 isoform b [Homo sapiens] 41 0.003
gi|18375632 HLA-B associated transcript-3 isoform b [Homo sapiens] 41 0.003
gi|18375630 HLA-B associated transcript-3 isoform b [Homo sapiens] 41 0.003
gi|149158692 HLA-B associated transcript-3 isoform a [Homo sapiens] 41 0.003
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 41 0.003
>gi|117306178 hypothetical protein LOC55731 [Homo sapiens]
Length = 562
Score = 1159 bits (2999), Expect = 0.0
Identities = 562/562 (100%), Positives = 562/562 (100%)
Query: 1 MLACLPGPGDLSFQLLSHTQMNTGLQKWDTTQKMRTAHYPTPAELDAYAKKVANNPLTIK 60
MLACLPGPGDLSFQLLSHTQMNTGLQKWDTTQKMRTAHYPTPAELDAYAKKVANNPLTIK
Sbjct: 1 MLACLPGPGDLSFQLLSHTQMNTGLQKWDTTQKMRTAHYPTPAELDAYAKKVANNPLTIK 60
Query: 61 IFPNSVKVPQRKHVRRTVNGLDTSAQRYSPYPTQAATKAGLLAIVKVPAKSILKDFDGTR 120
IFPNSVKVPQRKHVRRTVNGLDTSAQRYSPYPTQAATKAGLLAIVKVPAKSILKDFDGTR
Sbjct: 61 IFPNSVKVPQRKHVRRTVNGLDTSAQRYSPYPTQAATKAGLLAIVKVPAKSILKDFDGTR 120
Query: 121 ARLLPEAIMNPPVAPYATVAPSTLAHPQAQALARQQALQHAQTLAHAPPQTLQHPQGIPP 180
ARLLPEAIMNPPVAPYATVAPSTLAHPQAQALARQQALQHAQTLAHAPPQTLQHPQGIPP
Sbjct: 121 ARLLPEAIMNPPVAPYATVAPSTLAHPQAQALARQQALQHAQTLAHAPPQTLQHPQGIPP 180
Query: 181 PQALSHPQSLQQPQGLGHPQPMAQTQGLVHPQALAHQGLQHPHNPLLHGGRKMPDSDAPP 240
PQALSHPQSLQQPQGLGHPQPMAQTQGLVHPQALAHQGLQHPHNPLLHGGRKMPDSDAPP
Sbjct: 181 PQALSHPQSLQQPQGLGHPQPMAQTQGLVHPQALAHQGLQHPHNPLLHGGRKMPDSDAPP 240
Query: 241 NVTVSTSTIPLSMAATLQHSQPPDLSSIVHQINQFCQTRAGISTTSVCEGQIANPSPISR 300
NVTVSTSTIPLSMAATLQHSQPPDLSSIVHQINQFCQTRAGISTTSVCEGQIANPSPISR
Sbjct: 241 NVTVSTSTIPLSMAATLQHSQPPDLSSIVHQINQFCQTRAGISTTSVCEGQIANPSPISR 300
Query: 301 SLLINASTRVSTHSVPTPMPSCVVNPMEHTHAATAALPAAGPVNLPTGISRVPTGYPSDL 360
SLLINASTRVSTHSVPTPMPSCVVNPMEHTHAATAALPAAGPVNLPTGISRVPTGYPSDL
Sbjct: 301 SLLINASTRVSTHSVPTPMPSCVVNPMEHTHAATAALPAAGPVNLPTGISRVPTGYPSDL 360
Query: 361 KPVTWNQHQLAHLQQMCSEASGTPAPGLTGKHAAGRELAGPGFVGKAPAYPQELCLAQSF 420
KPVTWNQHQLAHLQQMCSEASGTPAPGLTGKHAAGRELAGPGFVGKAPAYPQELCLAQSF
Sbjct: 361 KPVTWNQHQLAHLQQMCSEASGTPAPGLTGKHAAGRELAGPGFVGKAPAYPQELCLAQSF 420
Query: 421 HLKPPLEKPTPSPPVNGMAAPLAYPNGHYFQPLWNNILPTPNSDSSGSQDLAMPFHGGQP 480
HLKPPLEKPTPSPPVNGMAAPLAYPNGHYFQPLWNNILPTPNSDSSGSQDLAMPFHGGQP
Sbjct: 421 HLKPPLEKPTPSPPVNGMAAPLAYPNGHYFQPLWNNILPTPNSDSSGSQDLAMPFHGGQP 480
Query: 481 TGAPLDCAAAPGAHYRAGTGGGPVASQNSLMQTVDYLSGDFQQACFREQSLAMLSKAHRA 540
TGAPLDCAAAPGAHYRAGTGGGPVASQNSLMQTVDYLSGDFQQACFREQSLAMLSKAHRA
Sbjct: 481 TGAPLDCAAAPGAHYRAGTGGGPVASQNSLMQTVDYLSGDFQQACFREQSLAMLSKAHRA 540
Query: 541 PGNRAPDPTESRSLHIQHPGYR 562
PGNRAPDPTESRSLHIQHPGYR
Sbjct: 541 PGNRAPDPTESRSLHIQHPGYR 562
>gi|117306174 hypothetical protein LOC55731 [Homo sapiens]
Length = 562
Score = 1159 bits (2999), Expect = 0.0
Identities = 562/562 (100%), Positives = 562/562 (100%)
Query: 1 MLACLPGPGDLSFQLLSHTQMNTGLQKWDTTQKMRTAHYPTPAELDAYAKKVANNPLTIK 60
MLACLPGPGDLSFQLLSHTQMNTGLQKWDTTQKMRTAHYPTPAELDAYAKKVANNPLTIK
Sbjct: 1 MLACLPGPGDLSFQLLSHTQMNTGLQKWDTTQKMRTAHYPTPAELDAYAKKVANNPLTIK 60
Query: 61 IFPNSVKVPQRKHVRRTVNGLDTSAQRYSPYPTQAATKAGLLAIVKVPAKSILKDFDGTR 120
IFPNSVKVPQRKHVRRTVNGLDTSAQRYSPYPTQAATKAGLLAIVKVPAKSILKDFDGTR
Sbjct: 61 IFPNSVKVPQRKHVRRTVNGLDTSAQRYSPYPTQAATKAGLLAIVKVPAKSILKDFDGTR 120
Query: 121 ARLLPEAIMNPPVAPYATVAPSTLAHPQAQALARQQALQHAQTLAHAPPQTLQHPQGIPP 180
ARLLPEAIMNPPVAPYATVAPSTLAHPQAQALARQQALQHAQTLAHAPPQTLQHPQGIPP
Sbjct: 121 ARLLPEAIMNPPVAPYATVAPSTLAHPQAQALARQQALQHAQTLAHAPPQTLQHPQGIPP 180
Query: 181 PQALSHPQSLQQPQGLGHPQPMAQTQGLVHPQALAHQGLQHPHNPLLHGGRKMPDSDAPP 240
PQALSHPQSLQQPQGLGHPQPMAQTQGLVHPQALAHQGLQHPHNPLLHGGRKMPDSDAPP
Sbjct: 181 PQALSHPQSLQQPQGLGHPQPMAQTQGLVHPQALAHQGLQHPHNPLLHGGRKMPDSDAPP 240
Query: 241 NVTVSTSTIPLSMAATLQHSQPPDLSSIVHQINQFCQTRAGISTTSVCEGQIANPSPISR 300
NVTVSTSTIPLSMAATLQHSQPPDLSSIVHQINQFCQTRAGISTTSVCEGQIANPSPISR
Sbjct: 241 NVTVSTSTIPLSMAATLQHSQPPDLSSIVHQINQFCQTRAGISTTSVCEGQIANPSPISR 300
Query: 301 SLLINASTRVSTHSVPTPMPSCVVNPMEHTHAATAALPAAGPVNLPTGISRVPTGYPSDL 360
SLLINASTRVSTHSVPTPMPSCVVNPMEHTHAATAALPAAGPVNLPTGISRVPTGYPSDL
Sbjct: 301 SLLINASTRVSTHSVPTPMPSCVVNPMEHTHAATAALPAAGPVNLPTGISRVPTGYPSDL 360
Query: 361 KPVTWNQHQLAHLQQMCSEASGTPAPGLTGKHAAGRELAGPGFVGKAPAYPQELCLAQSF 420
KPVTWNQHQLAHLQQMCSEASGTPAPGLTGKHAAGRELAGPGFVGKAPAYPQELCLAQSF
Sbjct: 361 KPVTWNQHQLAHLQQMCSEASGTPAPGLTGKHAAGRELAGPGFVGKAPAYPQELCLAQSF 420
Query: 421 HLKPPLEKPTPSPPVNGMAAPLAYPNGHYFQPLWNNILPTPNSDSSGSQDLAMPFHGGQP 480
HLKPPLEKPTPSPPVNGMAAPLAYPNGHYFQPLWNNILPTPNSDSSGSQDLAMPFHGGQP
Sbjct: 421 HLKPPLEKPTPSPPVNGMAAPLAYPNGHYFQPLWNNILPTPNSDSSGSQDLAMPFHGGQP 480
Query: 481 TGAPLDCAAAPGAHYRAGTGGGPVASQNSLMQTVDYLSGDFQQACFREQSLAMLSKAHRA 540
TGAPLDCAAAPGAHYRAGTGGGPVASQNSLMQTVDYLSGDFQQACFREQSLAMLSKAHRA
Sbjct: 481 TGAPLDCAAAPGAHYRAGTGGGPVASQNSLMQTVDYLSGDFQQACFREQSLAMLSKAHRA 540
Query: 541 PGNRAPDPTESRSLHIQHPGYR 562
PGNRAPDPTESRSLHIQHPGYR
Sbjct: 541 PGNRAPDPTESRSLHIQHPGYR 562
>gi|14249534 hypothetical protein LOC84915 [Homo sapiens]
Length = 452
Score = 152 bits (385), Expect = 6e-37
Identities = 164/568 (28%), Positives = 227/568 (39%), Gaps = 122/568 (21%)
Query: 1 MLACLPGPGDLSFQLLSHTQMNTGLQKWDTTQK-MRTAHYPTPAELDAYAKKVANNPLTI 59
MLACL + Q L+ + L+K + M ++ YP+PAELDAYA+KVAN+PL+I
Sbjct: 1 MLACLQRTQNAPGQHLACPSKSLELRKCEAVASAMHSSRYPSPAELDAYAEKVANSPLSI 60
Query: 60 KIFPNSVKVPQRKHVRRTVNGLDTSAQRYSPYPTQAATKAGLLAIVKVPAKSILKDFDGT 119
KIFP +++VPQ KH+ RTVNG DT QRYSPYP A GLLAIVK
Sbjct: 61 KIFPTNIRVPQHKHLSRTVNGYDTGGQRYSPYPQHTAGYQGLLAIVKA------------ 108
Query: 120 RARLLPEAIMNPPVAPYATVAPSTLAHPQAQALARQQALQHAQTLAHAPPQTLQHPQGIP 179
A+ + A A A S L + + A + P TL P P
Sbjct: 109 -------AVSSSSTAAPAGPAKSVLKSAEGKRTKLSPAAVQVGIAPYPVPSTLG-PLAYP 160
Query: 180 PPQALSHPQSLQQPQGLGHPQPMAQTQGLVHPQALAHQGLQHPHNPLLHGGRKMPDSDAP 239
P P++ P GL P A T V P GR +P P
Sbjct: 161 KP-----PEAPAPPPGL----PAAATAASVIPLP----------------GRGLP---LP 192
Query: 240 PNVTVSTSTIPLSMAATLQHSQPPDLSSIVHQINQFCQTRAGISTTSVCEGQ-IANPSPI 298
P S P + S+++Q+NQ CQ + C+G I +PSP
Sbjct: 193 P-------------------SNLPSIHSLLYQLNQQCQAPG--AAPPACQGMAIPHPSPA 231
Query: 299 SRSLLINASTRVSTHSVPTPMPSCVVNPMEHTHAATAALPAAGPVNLPTGISRVPTGYP- 357
+ S +S +P C E AT AL AG P GY
Sbjct: 232 KHGPV--PSFPSMAYSAAAGLPDCRKGT-ELGQGATQALTLAGAAK--------PAGYAD 280
Query: 358 SDLKPVTWNQHQLAHLQQMCSEASGTPAPGLTGKHAAGRELAGPGFVGKAPAYPQELCLA 417
S L + W Q P P + +G +A K+P E C
Sbjct: 281 SGLDYLLWPQKP-------------PPPPPQPLRAYSGSTVAS-----KSP----EACGG 318
Query: 418 QSFHLKPPLEKPTPSPPVNGMAAPLAYPNGHYFQPLWNNILPTPNSDSSGSQDLAMPFHG 477
+++ E+ + SP G+ P ++ G YF WN++L TP SD +
Sbjct: 319 RAY------ERASGSPLNCGVGLPTSFTVGQYFAAPWNSVLVTPTSDYYNPAAAVVVTEL 372
Query: 478 GQPTGAPLDCAAAPGAHYRAGTGGGPVASQ---NSLMQTVDYLSGDFQQACFREQSLAML 534
G L A P A +G V + +S +Q+++YL D + C +EQ ML
Sbjct: 373 GPGAAREL---AGPPADALSGLPSKSVCNTSVLSSSLQSLEYLINDIRPPCIKEQ---ML 426
Query: 535 SKAHRAPGNRAPDPTESRSLHIQHPGYR 562
K + P + + HI+ P YR
Sbjct: 427 GKGYETVA--VPRLLDHQHAHIRLPVYR 452
>gi|21327715 transcription elongation regulator 1 isoform 1 [Homo
sapiens]
Length = 1098
Score = 59.3 bits (142), Expect = 9e-09
Identities = 68/248 (27%), Positives = 97/248 (39%), Gaps = 31/248 (12%)
Query: 122 RLLPEAIMNPPVAPYATVAPSTLAHPQAQALARQQALQHAQTLAHAPPQTLQHPQGIPPP 181
+++ ++ + P +A A V A QAQA A+ QA AQ A A Q Q
Sbjct: 166 KVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQA--QA 223
Query: 182 QALSHPQSLQQPQGLGHPQPMAQTQGLVHPQALAHQGLQHPHNPLLHGGRKMPDSDAPPN 241
QA + Q+ Q Q Q AQ Q V QA+ G P S + P+
Sbjct: 224 QAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAV---GASTPTTSSPAPAVSTSTSSSTPS 280
Query: 242 VTVSTSTIPLSMAATLQHSQPPDLSSIVHQINQFCQTRAGISTTSVCEGQIANPSPISRS 301
T ST+T S+A T+ D Q + ++T +V ++ P+P
Sbjct: 281 STTSTTTTATSVAQTVSTPTTQD---------QTPSSAVSVATPTV---SVSTPAP---- 324
Query: 302 LLINASTRVSTHSVPTPMPSCVVNPMEHT-HAATAALPAAGPVNLPTGISRVP-TGYPSD 359
T +VP P P + + H+ T A+PA PV +P RVP G P
Sbjct: 325 ------TATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPP--FRVPLPGMPIP 376
Query: 360 LKPVTWNQ 367
L V Q
Sbjct: 377 LPGVAMMQ 384
>gi|91208418 transcription elongation regulator 1 isoform 2 [Homo
sapiens]
Length = 1077
Score = 58.5 bits (140), Expect = 2e-08
Identities = 67/244 (27%), Positives = 96/244 (39%), Gaps = 31/244 (12%)
Query: 122 RLLPEAIMNPPVAPYATVAPSTLAHPQAQALARQQALQHAQTLAHAPPQTLQHPQGIPPP 181
+++ ++ + P +A A V A QAQA A+ QA AQ A A Q Q
Sbjct: 166 KVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQA--QA 223
Query: 182 QALSHPQSLQQPQGLGHPQPMAQTQGLVHPQALAHQGLQHPHNPLLHGGRKMPDSDAPPN 241
QA + Q+ Q Q Q AQ Q V QA+ G P S + P+
Sbjct: 224 QAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAV---GASTPTTSSPAPAVSTSTSSSTPS 280
Query: 242 VTVSTSTIPLSMAATLQHSQPPDLSSIVHQINQFCQTRAGISTTSVCEGQIANPSPISRS 301
T ST+T S+A T+ D Q + ++T +V ++ P+P
Sbjct: 281 STTSTTTTATSVAQTVSTPTTQD---------QTPSSAVSVATPTV---SVSTPAP---- 324
Query: 302 LLINASTRVSTHSVPTPMPSCVVNPMEHT-HAATAALPAAGPVNLPTGISRVP-TGYPSD 359
T +VP P P + + H+ T A+PA PV +P RVP G P
Sbjct: 325 ------TATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPP--FRVPLPGMPIP 376
Query: 360 LKPV 363
L V
Sbjct: 377 LPGV 380
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 56.6 bits (135), Expect = 6e-08
Identities = 112/416 (26%), Positives = 152/416 (36%), Gaps = 77/416 (18%)
Query: 118 GTRARLLPEA--------IMNPPVAPYAT----VAPSTLAHPQAQALARQQALQHAQTLA 165
GT+AR +P PP P AT PS A P Q L A +Q
Sbjct: 311 GTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQ--- 367
Query: 166 HAPPQTLQHPQGIPPP----QALSHPQSLQQPQGLGHPQPMAQTQGLVHPQALAHQGLQH 221
APP P PP + P SL P P P+A L +L LQ
Sbjct: 368 -APPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLA-LSSLQATTSLGSPTLQA 425
Query: 222 PHNPLLHGGRKMPDSDAPPNVTVSTS------TIPLSMAAT--LQHSQPPDLSSI----- 268
H+ L R+ S P+ ST PLS+ A+ LQ S P +S +
Sbjct: 426 THSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLT 485
Query: 269 VHQINQFCQTRAGISTTSVCEGQIANPSPISRSLLINASTRVSTHSVPTP----MPSCVV 324
+H + Q + A S + I P ++S L S + S+ TP +PS
Sbjct: 486 IHPL-QALSSLASHSPQAPLSSLIMPPLE-TQSSLAPPSLQTPPASLTTPPLENLPSLAP 543
Query: 325 NPMEHT-------HAATAALPAAGPVNL-PTGISRVPTGYPSDL-KPVTWNQHQLAHLQQ 375
P++ H T PA P+ P+ ++ P PS + P LA
Sbjct: 544 PPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALA---- 599
Query: 376 MCSEASGTPAPGLTGKHAAGRELAGPGFVGKAPAYPQELCLAQSFHLKPPLEKPTPSPPV 435
G P+P L+ LA P P P L L PPL+ P PSPP
Sbjct: 600 -SPPLQGLPSPPLS-------PLATP-----PPQAPPXLAL-------PPLQAP-PSPPA 638
Query: 436 NGMAAPLAYPNGHYFQPLWNNILPTPNSDSSGSQDLAMPFHGGQPTGAPLDCAAAP 491
+ +PLA P+ L ++L P S S + PF P P+ +A P
Sbjct: 639 SPPLSPLATPSPQAPNALAVHLLQAPFSPPP-SPPVQAPF--SPPASPPVSPSATP 691
Score = 35.0 bits (79), Expect = 0.18
Identities = 104/414 (25%), Positives = 144/414 (34%), Gaps = 73/414 (17%)
Query: 125 PEAIMNPPVAPYATV---APSTLA------------HPQAQAL----ARQQALQHAQTLA 165
P +PP++P AT AP+ LA P QA A A +
Sbjct: 634 PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPS 693
Query: 166 HAPPQTLQHPQGIPPPQALSHPQSLQQPQGLGHPQPMAQTQGLVHPQALAHQGLQHPHNP 225
APP P +PP S P S P P+A V P A P +P
Sbjct: 694 QAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPA----SPPMSP 749
Query: 226 LLHGGRKMPDSDAPPNVTVSTS---TIPLSMAATLQHSQPPDLSSIVHQINQFCQTRAGI 282
++P A P + V S ++P+S A PP L++ Q A
Sbjct: 750 SATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQ--------ALP 801
Query: 283 STTSVCEGQIANPSPISRSLLINASTRVSTHSVPTPM-PSCVVNPMEHTHAATAALPAAG 341
S + GQ +P S S AS +S + P P P + P+ + PA+
Sbjct: 802 SPPASFPGQ----APFSPS----ASLPMSPLATPPPQAPPVLAAPLLQVPPSP---PASP 850
Query: 342 PVNLPTGISRVPTGYPSDLKPVTWNQHQLAHLQQMCSEASGTPAPGLTGKHAAGRELAGP 401
+ P R PT P V+ + LA S +P+ L+G AG
Sbjct: 851 TLQAP---RRPPT--PGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHS---- 901
Query: 402 GFVGKAPAYPQELCLAQSFHLKPPLEKPTPSPPVNGMAA--PLAYPNGH----YFQPLWN 455
A + P+EL + + P PP +AA P A+ G F+
Sbjct: 902 ---SSATSTPEEL---RGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPG 955
Query: 456 NILPTPNSDSSGSQDLAMPFHGGQPTGAPLDCAAAPGA---HYRAGTGGGPVAS 506
LP P + GS D + T P APGA GT GG A+
Sbjct: 956 APLPWPPATGPGSADGLCTIY---ETEGPESATPAPGALDPGPSPGTSGGKAAA 1006
>gi|222352122 hypothetical protein LOC284297 [Homo sapiens]
Length = 1573
Score = 49.7 bits (117), Expect = 7e-06
Identities = 76/327 (23%), Positives = 104/327 (31%), Gaps = 58/327 (17%)
Query: 119 TRARLLPEAIMNPPVAPYATVAPSTLAHPQAQALARQQALQHAQTLAHAPPQTLQHPQGI 178
T + ++P+ P P+ T+ P+T H H T H P T+ H I
Sbjct: 1210 THSTMIPDPTTTPQ--PFTTMQPTTTPH---------STTPHPTTTPH--PTTITHSTMI 1256
Query: 179 PPPQALSHPQSLQQPQGLGHPQPMAQTQGLVHPQALAHQGLQHPHNPLLHGGRKMPDSDA 238
P P P + QP + HP HP H PH P
Sbjct: 1257 PDPTTTPQPFTTMQPTTMPHPTTTPHPTTTPHPTTTPHP-TTTPH----------PTMTP 1305
Query: 239 PPNVTVSTSTIPLSMAATLQHSQPPDLSSIVHQINQFCQTRAGISTTSVCEGQIANPSPI 298
P T +T P T H PD SS T G +S PS
Sbjct: 1306 DPTTTPYPTTTP--DPTTTPHPTTPDPSSTPVITTVSLPTSLGTELSSPTLAPTVKPSLH 1363
Query: 299 SRSLLINASTRVSTHSVPT--PMPSCVVNPMEHTHAATAALPAAGPVNLPTGISRVPTGY 356
+ + ST +PT P P+ +P + AT+ P L T + P
Sbjct: 1364 PQLTFTAPAPHTSTSQIPTLEPSPALESSP-SRSSTATSMDP------LSTEDFKPPRSQ 1416
Query: 357 PSDLKPVTWNQHQLAHLQQMCSEASGTPAPGLT-GKHAAGRELAGPGFVGKAPAY---PQ 412
+L P H S+ + +P P L+ H P +G P P
Sbjct: 1417 SPNLTPPP------THTPHSASDLTVSPDPLLSPTAHPLDHPPLDPLTLGPTPGQSPGPH 1470
Query: 413 ELCLAQSFHLKPPLEKPTPSPPVNGMA 439
C+A P+PPV MA
Sbjct: 1471 GPCVA-------------PTPPVRVMA 1484
>gi|148612809 WNK lysine deficient protein kinase 1 [Homo sapiens]
Length = 2382
Score = 49.3 bits (116), Expect = 9e-06
Identities = 86/387 (22%), Positives = 145/387 (37%), Gaps = 46/387 (11%)
Query: 137 ATVAPSTLAHPQAQALARQQALQHAQTLAHAPPQTLQHPQGIPPPQALSHPQSLQQPQGL 196
+ ++ T+ Q ++ + + QT+++ H G P S Q+ QP G+
Sbjct: 648 SVLSDGTVDSGQGSSVFTESRVSSQQTVSYGSQHEQAHSTGTVPGHIPSTVQAQSQPHGV 707
Query: 197 GHPQPMAQTQGLVHPQALAHQGLQHPHNPLLHGGRKMP-DSDAPPNVTVSTS---TIPLS 252
P +AQ Q P + + G+ P+ H ++ APP TV S T S
Sbjct: 708 YPPSSVAQGQSQGQPSSSSLTGVS-SSQPIQHPQQQQGIQQTAPPQQTVQYSLSQTSTSS 766
Query: 253 MAATLQHSQPPDLSSIVHQINQFCQTRAGISTTSVCEGQIANPSPISRSLL---INASTR 309
A T Q P ++ Q++ Q ++ +G+ P S++ A
Sbjct: 767 EATTAQPVSQPQAPQVLPQVSAGKQLPVSQPVPTI-QGEPQIPVATQPSVVPVHSGAHFL 825
Query: 310 VSTHSVPTP-MPSCVVN--PMEHTHAATAALPAAG-PVNLPTGISR-------------- 351
+PTP +P V+ P+ H +TA + P+ + GI++
Sbjct: 826 PVGQPLPTPLLPQYPVSQIPISTPHVSTAQTGFSSLPITMAAGITQPLLTLASSATTAAI 885
Query: 352 ------VPTGYPSDLKPVTWNQHQLAHLQQMCSEASGTPAPGLTGKHA----AGRELAGP 401
VP+ P+ L+PVT Q+ H Q + P G+ A + ++
Sbjct: 886 PGVSTVVPSQLPTLLQPVTQLPSQV-HPQLLQPAVQSMGIPANLGQAAEVPLSSGDVLYQ 944
Query: 402 GFVGK-APAYPQELCLAQSFHLKPPLEKPT---PSPPVNGMAAPLAYPNGHYFQPLWNNI 457
GF + P YP + +A S ++ T P P +A P +P QP +
Sbjct: 945 GFPPRLPPQYPGDSNIAPSSNVASVCIHSTVLSPPMPTEVLATPGYFPT--VVQPYVESN 1002
Query: 458 LPTPNSDSSGSQDLAMPFHGGQPTGAP 484
L P G ++ P GG AP
Sbjct: 1003 LLVPMGGVGGQVQVSQP--GGSLAQAP 1027
Score = 30.4 bits (67), Expect = 4.5
Identities = 32/149 (21%), Positives = 56/149 (37%), Gaps = 11/149 (7%)
Query: 119 TRARLLPEAIMNPPVAPYATVAPSTLAHPQAQALARQQALQHAQTLAHAPPQTLQHPQGI 178
T+ +P A++ PP AP + + ++ + +L + PQ + G
Sbjct: 2103 TKLGKVPPAVIIPPAAPLS-------GRRRRPTKSKGSKSSRSSSLGNKSPQLSGNLSGQ 2155
Query: 179 PPPQALSHPQSLQQPQGLGHPQPMAQTQGLVHPQALAHQGLQHPHNPLLHGGRKMPDSDA 238
L HPQ P G P + L+ P + G +P A
Sbjct: 2156 SAASVL-HPQQTLHPPG---NIPESGQNQLLQPLKPSPSSDNLYSAFTSDGAISVPSLSA 2211
Query: 239 PPNVTVSTSTIPLSMAATLQHSQPPDLSS 267
P T ST+T+ ++ + +QPP ++S
Sbjct: 2212 PGQGTSSTNTVGATVNSQAAQAQPPAMTS 2240
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 45.8 bits (107), Expect = 1e-04
Identities = 101/420 (24%), Positives = 139/420 (33%), Gaps = 75/420 (17%)
Query: 83 TSAQRYSPYPTQAAT-KAGLLAIVKVPAKSILKDFDGTRARLLPEAIMNPPVAPYATVAP 141
T+A+ S Y T A+ G +++ P +K+ T L+P A N PVAP +P
Sbjct: 661 TTAKGTSTYTTTASPFLEGTVSLA--PKNHPVKEGTLTTLPLVPTASENCPVAP----SP 714
Query: 142 STLAHPQAQALARQQALQHAQTLAHAPPQTLQHPQGIPPPQALSHPQSLQQPQGLGHPQP 201
P A TL AP + P+ +P P S P + G P
Sbjct: 715 QNTCAPLA-------------TLVLAP----EIPKSVPSP---SLPPA-------GTPPG 747
Query: 202 MAQTQGLVHPQALAHQGLQHPHNPLLHGGRKMPDSDAPPNVTVSTSTIPLSMAATLQHSQ 261
+ G+ H ALA P G S ++ S PL ++ + Q +
Sbjct: 748 TKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKR 807
Query: 262 PPDLSSIVHQINQFCQTRAGISTTSVCEGQIANP-SPISRSLLINAS--------TRVST 312
PP T+ G + G +++P SP+ S L S + +T
Sbjct: 808 PP--------------TKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATT 853
Query: 313 HSVPTPMPSCVVNPMEHTHAATAALPAAGPVNLPT-GISRVPTGYPSDLKPVTWNQHQLA 371
HS P P P T + + P PT + +P P L+
Sbjct: 854 HSPTPPSPKGAPTPSAVTPLSPKGV-TLPPKETPTPSVVNLPFPKEGPATPAPKQAPALS 912
Query: 372 HLQQMCSEASGTPAPGLTGKHAAGRELAGPGFVGKAPAYPQELCLAQSFHLKPPLEKPTP 431
+A TPAP G A+ P P P+ S P TP
Sbjct: 913 MTSSSPKKARATPAP--KGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATP 970
Query: 432 SPPVNGMAAPLAYPNGHYFQPLWNNILPTPNSDSSGSQDLAMPFHGGQPTGAPLDCAAAP 491
P G A P P G P TP S G A P P GAP A P
Sbjct: 971 PSPKGGPATP--SPKGAPTPP-----AATPPSPKGGP---ATP----SPKGAPTPPAVTP 1016
Score = 42.7 bits (99), Expect = 9e-04
Identities = 95/439 (21%), Positives = 146/439 (33%), Gaps = 58/439 (13%)
Query: 119 TRARLLPEAIMNPPVAPYATVAPSTLAHPQAQALARQQALQHAQTLAHAPPQTLQHPQGI 178
T A L P+ + PP A PS P A ++ + P T +G
Sbjct: 1538 TPATLAPKEALIPP----AMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGA 1593
Query: 179 PPPQALSHPQSLQQPQGLGHPQPMAQTQGLVHPQALAHQGLQHPHNPLLHGGRKMPDSDA 238
P P+ L P ++ P P P A T P +P K P + A
Sbjct: 1594 PSPKELLIPPAVTSPSPKEAPTPPAVT----------------PPSP-----EKGPATPA 1632
Query: 239 PPNVTVSTSTIPLSMAATLQHSQPPDLSSIVHQINQFCQTRAGISTTSVCEGQIANPSPI 298
P S P S+ P +S+ + G + +G A P
Sbjct: 1633 PKGTPTSPPVTPSSL-----KDSPTSPASVT--------CKMGATVPQASKGLPAKKGPT 1679
Query: 299 SRSLLINASTRVSTHSVPTPMPSCVVNPMEHTHAATAALPAAGPVNLPTGISRVPTGYPS 358
+ ++ A ST + P P +AT+ P + T P+
Sbjct: 1680 ALKEVLVAPAPESTPIITAPTRK---GPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPA 1736
Query: 359 DLKPVTWNQHQLAHLQQMCSEASGTPAP----GLTGKHAAGRELAGP----GFVGKAPAY 410
L PV + + A + G AP T AA E P V AP+
Sbjct: 1737 PLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSP 1796
Query: 411 PQELCLAQS-FHLKPPLEKPTPSPP---VNGMAAPLAYPNGHYFQPLWNNILPTPNSDSS 466
P L LA S PP ++ PS P + + PLA + PL I P P S
Sbjct: 1797 PVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPL---IPPEPISGGV 1853
Query: 467 GSQDLAMPFHGGQPTGAPLDCAAAPGAHYRAGTGGGPVASQNSLMQTVDYLSGDFQQACF 526
Q + + + G P+ +A + G G + + + ++ D QA
Sbjct: 1854 PFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELE--EQDSTQATT 1911
Query: 527 REQSLAMLSKAHRAPGNRA 545
++ LA ++ P ++A
Sbjct: 1912 QQAQLAAAAEIDEEPVSKA 1930
Score = 42.0 bits (97), Expect = 0.001
Identities = 91/381 (23%), Positives = 116/381 (30%), Gaps = 44/381 (11%)
Query: 125 PEAIMNPPVAPYATVAPSTLAHPQAQALARQQALQHAQTLAHAPPQTLQHP--QGIPPPQ 182
P+ PP A PS P A L + A TL +P P +G P P
Sbjct: 1029 PKGASTPPAA----TPPSPKGSPAATPLPKGAPTTPAATLP-SPKGGPATPSLKGAPTPP 1083
Query: 183 ALSHPQSL---QQPQGLGHPQPMAQTQ-----GLVHPQALAHQGLQHPHNPLLHGGRKMP 234
A + P P G P P A T GL P P GG P
Sbjct: 1084 AATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATP 1143
Query: 235 DSDAPPNVTVST--------STIPLSMAATLQHSQPPDLSSIVHQINQFCQTRAGISTTS 286
P +T +T P A T + PP + + +T
Sbjct: 1144 PPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP 1203
Query: 287 VCEGQIANPSPISRSLLINASTRVSTHSVPTPMPSCVVNPMEHTHAATAALPAAGPVNLP 346
+G +A PSP A+ + TP P T AAT P GP P
Sbjct: 1204 SPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPT----TPAATPPSPKGGPATPP 1259
Query: 347 T-GISRVPTGYPSDLKP-VTWNQHQLAHLQQMCSEASGTPAPGLTG-KHAAGRELAGPGF 403
G P P LK + H+ A + + S P + K A A P
Sbjct: 1260 PKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPS 1319
Query: 404 VGKAPAYPQELCLAQSFHLKPPLEKPTPSPPVNGMAAPLAYPNGHYFQPLWNNILPTPNS 463
+P P PP K P+PP +P P P TP+S
Sbjct: 1320 PKGSPGTP------------PP--KGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSS 1365
Query: 464 DSSGSQDLAMPFHGGQPTGAP 484
+ A P H G P P
Sbjct: 1366 KEGPTPPAATPSHKGGPAMTP 1386
Score = 33.1 bits (74), Expect = 0.70
Identities = 83/356 (23%), Positives = 100/356 (28%), Gaps = 80/356 (22%)
Query: 165 AHAPPQTLQHPQGIPPPQALSHPQSLQQPQGLGHPQPMAQTQGL-VHPQALAHQGLQHPH 223
A PP P P P+ S P + P G P +G P A P
Sbjct: 1013 AVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPA 1072
Query: 224 NPLLHG----------------------GRKMPDSDAPPNVTVSTSTIPLSMAATLQHSQ 261
P L G G MP + PP+ +T P A T +
Sbjct: 1073 TPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAAT 1132
Query: 262 PPDLSSIVHQINQFCQTRAGISTTSVCEGQIANPSPISRSLLINASTRVSTHSVPTPMPS 321
PP + +T +G +A P P A+ + TP P
Sbjct: 1133 PPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPK 1192
Query: 322 CVVNPMEHTHAATAALPAAG-PVNLPTGISRVPTGYPSDLKPVTWNQHQLAHLQQMCSEA 380
T AAT P G P G P P K
Sbjct: 1193 GAPT----TPAATPPSPKGGLATPSPKGAPTTPAATPPSPK-----------------GG 1231
Query: 381 SGTPAPGLTGKHAAGRELAGPGFVGKAPAYPQELCLAQSFHLKPPLEKPTP---SPP--V 435
TP+P K A A P PA P PP PTP +PP
Sbjct: 1232 LATPSP----KGAPTTPAATPPSPKGGPATP------------PPKGAPTPPAATPPSLK 1275
Query: 436 NGMAAPLAYPNGHYFQPLWNNILPTPNSDSSGSQDLAMPFHGGQPTGAPLDCAAAP 491
G+A P H P N + TP S G P GAP AA P
Sbjct: 1276 GGLATP-----PHKGAP--NPAVVTPPSPKGGPAT-------SPPKGAPTPPAATP 1317
Score = 30.0 bits (66), Expect = 5.9
Identities = 80/367 (21%), Positives = 116/367 (31%), Gaps = 90/367 (24%)
Query: 141 PSTLAHPQAQALARQQALQHAQTLAHAPPQTLQHPQGIPPPQALSHPQSLQQPQGLGHPQ 200
P+ + P + + A T A P + + G PPP+ P ++ P G P
Sbjct: 1289 PAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPT 1348
Query: 201 PMAQT-------------QGLVHPQAL-AHQG--LQHPHNPLLHGGRKMPDSDAPPNVTV 244
A T +G P A +H+G P +P ++ P +P
Sbjct: 1349 LPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSP-----KRGPAIPSPKGDPT 1403
Query: 245 STSTIPLSMAATLQHSQPPDLSSIVHQINQFCQTRAGISTTSVCEGQIANPSPISRSLLI 304
S + IPLS + P TR G +T S +G + P+ SL
Sbjct: 1404 SPAVIPLSPKKA--PATP--------------VTREGAATPS--KGDLTPPAVTPVSLKK 1445
Query: 305 NASTRVSTHSVPTP-----------MPSCVVNPMEHTHAATAALPAAGPVN-LPTGISRV 352
+T TP P P AT++ P P P G +
Sbjct: 1446 APATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTL 1505
Query: 353 PTGYPSDLK--PVTWNQHQ-----------------LAHLQQMCSEASGTPAPGLT---- 389
P PS K P T + + LA + + A P+P T
Sbjct: 1506 PAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIP 1565
Query: 390 ----------GKHAAGRELAGPGFVGKAPAYPQELCLAQSFHLKPPLEKP-----TPSPP 434
K A+ P AP+ P+EL + + P E P TP P
Sbjct: 1566 TPKEAPATPSSKEASSPPAVTPSTYKGAPS-PKELLIPPAVTSPSPKEAPTPPAVTPPSP 1624
Query: 435 VNGMAAP 441
G A P
Sbjct: 1625 EKGPATP 1631
>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
Length = 788
Score = 44.7 bits (104), Expect = 2e-04
Identities = 66/231 (28%), Positives = 90/231 (38%), Gaps = 26/231 (11%)
Query: 131 PPVAPYATVAPSTLAHPQAQALARQQALQHAQTLAHAPPQTLQHPQGIPPPQALSHPQSL 190
P P A PS L PQ+Q Q + AQ L P + + Q PP + + P +
Sbjct: 305 PQQPPVAQNQPSQLP-PQSQT---QPLVSQAQAL----PGQMLYTQ--PPLKFVRAPMVV 354
Query: 191 QQPQGLGHPQPMAQTQGLVHPQALAHQ----GLQHPHNPLLHGGRKMPDSDAPPNVTVS- 245
QQP QP Q Q A A Q G+Q L GG + + PP VS
Sbjct: 355 QQPP----VQPQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIR-ARFPPTTAVSA 409
Query: 246 --TSTIPLSMAATLQHSQP--PDLSSIVHQINQFCQTRAGISTTSVCEGQIANPSPISRS 301
+S+IPL Q SQ P LSS Q QT + Q PS S
Sbjct: 410 IPSSSIPLGRQPMAQVSQSSLPMLSS--PSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNS 467
Query: 302 LLINASTRVSTHSVPTPMPSCVVNPMEHTHAATAALPAAGPVNLPTGISRV 352
+ + + +P+P P +P+ ++P+ GP+N P S V
Sbjct: 468 NVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSV 518
Score = 36.6 bits (83), Expect = 0.063
Identities = 65/264 (24%), Positives = 94/264 (35%), Gaps = 34/264 (12%)
Query: 148 QAQALARQQALQHAQTLAHAPPQTLQHPQGIPPPQALSHPQSLQQPQGLGHPQ------- 200
Q Q +QQALQ AQ PP +Q PQ PP + + PQ LQQ H Q
Sbjct: 254 QQQQQQQQQALQ-AQPPIQQPP--MQQPQ---PPPSQALPQQLQQMHHTQHHQPPPQPQQ 307
Query: 201 ------------PMAQTQGLV-HPQALAHQGL-QHPHNPLLHGGRKMPDSDAPPNVTVST 246
P +QTQ LV QAL Q L P + + P V
Sbjct: 308 PPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQ 367
Query: 247 STIPLSMAATLQHSQPPDLSSIVHQINQ-FCQTRAGISTTSVCEGQIANPSPISRSLLIN 305
+ + + AA + P + I + Q RA T+ ++ P+ R +
Sbjct: 368 TAVQTAQAAQM---VAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQ 424
Query: 306 ASTRVSTHSVPTPMPSCVVNPMEHTHAATAALPAAG-PVNLP-TGISRVPTGYPSDLKPV 363
S + S + +P P V + P G P + P + +S P PS P
Sbjct: 425 VS-QSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPS 483
Query: 364 TWNQHQLAHLQQMCSEASGTPAPG 387
Q + + + P+PG
Sbjct: 484 PSPQPSQSPVTARTPQNFSVPSPG 507
Score = 34.3 bits (77), Expect = 0.31
Identities = 79/373 (21%), Positives = 119/373 (31%), Gaps = 89/373 (23%)
Query: 148 QAQALARQQALQHAQTLAHAPPQTLQHPQ---------GIPPPQALSHPQSLQQPQGLGH 198
Q Q +QQ QH L H Q +Q Q + Q Q QQ Q L
Sbjct: 207 QQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQAL-Q 265
Query: 199 PQPMAQTQGLVHPQALAHQGLQHPHNPLLHGGRKMPDSDAPPNVTVSTSTIPLSMAATLQ 258
QP Q + PQ Q L + H P PP Q
Sbjct: 266 AQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQP----PP-----------------Q 304
Query: 259 HSQPPDLSSIVHQINQFCQTRAGISTTSVCEGQIANPSP---------ISRSLLINASTR 309
QPP + Q+ QT+ +S GQ+ P + + + +
Sbjct: 305 PQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQ 364
Query: 310 VSTHSVPTPMPSCVVNPMEHTHAATAALPAAG---PVNLP--TGISRVPTGYPSDLKPVT 364
+V T + +V P T AL G P T +S +P+ +
Sbjct: 365 QQQTAVQTAQAAQMVAP--GVQMITEALAQGGMHIRARFPPTTAVSAIPS------SSIP 416
Query: 365 WNQHQLAHLQQMCSEASGTPAPGLTGKHAAGRELAGPGFVGKAPAYPQELCLAQSFHLKP 424
+ +A + Q +P+PG Q++ QS P
Sbjct: 417 LGRQPMAQVSQSSLPMLSSPSPG------------------------QQVQTPQSM---P 449
Query: 425 PLEKPTPSPPVNGMAAPLAYPNGHYFQ---PLWNNILPTPNSDSSGSQDLA-MPFHGGQP 480
P +P+P P P + PN + P ++ LP+P+ S S A P + P
Sbjct: 450 PPPQPSPQP-----GQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVP 504
Query: 481 TGAPLDCAAAPGA 493
+ PL+ P +
Sbjct: 505 SPGPLNTPVNPSS 517
>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
Length = 2217
Score = 43.9 bits (102), Expect = 4e-04
Identities = 51/166 (30%), Positives = 69/166 (41%), Gaps = 23/166 (13%)
Query: 132 PVAPYATVAPSTLAHPQAQALARQQALQHAQTLAHAPPQTLQHPQGIPPPQALSHPQSLQ 191
P +P+ TV PQ AL Q L PPQ + PQ PPQ + PQ +
Sbjct: 925 PPSPHHTVQNMRATPPQP-ALPPQPTL---------PPQPVLPPQPTLPPQPVLPPQPTR 974
Query: 192 QPQGLGHPQPMAQTQGLVHPQ---ALAHQGLQHPHNPLLHGGRKMPDSD------APPNV 242
PQ + PQPM Q ++ PQ + + LQ PH P P S AP V
Sbjct: 975 PPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQ-PHLPEQAAPAATPGSQILLGHPAPYAV 1033
Query: 243 TVSTS--TIPLSMAATLQHSQPPDLSSIVHQ-INQFCQTRAGISTT 285
V+ T+P+ AA L P L + + QF + A +S +
Sbjct: 1034 DVAAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSAS 1079
Score = 42.4 bits (98), Expect = 0.001
Identities = 78/325 (24%), Positives = 111/325 (34%), Gaps = 62/325 (19%)
Query: 130 NPPVAPYATVAPSTLAHPQAQALARQQALQHAQTLAHAPPQTLQHPQGIPPPQALSHPQS 189
NPP AP A +APS+ P AL + A T+ T G PQ L+
Sbjct: 1375 NPPGAPPAPLAPSS---PPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELE 1431
Query: 190 LQQPQGLGHPQPMAQTQGLV--------HPQALAHQGLQHPHNPL--------LHGGRKM 233
QP H P+A Q LV P+A + + P PL H G
Sbjct: 1432 TSQPLAETHEAPLA-VQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQ 1490
Query: 234 PDSDAPP--------NVTVSTSTIPLSMAATLQHSQPPDLSSIVHQINQFCQTRAGISTT 285
P P V+++TS +P + L + PP S + + R G
Sbjct: 1491 PALGQPAPLLPAAVGAVSLATSQLP---SPPLGPTVPPQPPSALESDGEGPPPRVGF--- 1544
Query: 286 SVCEGQIANPSPISRSLLINASTRVSTHSVPTPM----------PSCVVNPMEHTHAATA 335
+ I + R+LL S+ S TP+ P P
Sbjct: 1545 --VDSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQPRSEVCGGDL 1602
Query: 336 ALP------AAGPVNLPTGISRVPTGYPSDLKPVTWNQHQLAHLQQMCSEASGTPAPGLT 389
ALP +G V LP P S+L P + M +E+S +
Sbjct: 1603 ALPPVPKEAVSGRVQLPQ-----PLVEKSELAPTRGAVMEQGTSSSMTAESS---PRSML 1654
Query: 390 GKHAAGRELAGPGFVGKAPAYPQEL 414
G GR++A V P+ PQ++
Sbjct: 1655 GYDRDGRQVASDSHV--VPSVPQDV 1677
Score = 31.6 bits (70), Expect = 2.0
Identities = 43/179 (24%), Positives = 60/179 (33%), Gaps = 32/179 (17%)
Query: 258 QHSQPPDLSSIVHQINQFCQTRAGISTTSVCEGQIANPSPISRSLLINASTRVSTHSVPT 317
QH PP L + + +G +T + Q + S + SL + P+
Sbjct: 596 QHLLPPTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSL---------ADAAPS 646
Query: 318 PMPSCVVNPMEHTHAATAALPAAGPVNLPTGISRVPTG-YPSDLKPVTWNQHQLAHLQQM 376
P P+ +LP+ G PT +P G P+ P + QH
Sbjct: 647 PAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQH---FPDPA 703
Query: 377 CSEASGTPAPGLTGKHAAGRELAGPGFVGKAPAYPQELCLAQSFHLKPPLEKPTPSPPV 435
S A P P GPG PA P + PPL +PTP P V
Sbjct: 704 MSFAPVLPPPSTPMP-------TGPG----QPAPPGQQ--------PPPLAQPTPLPQV 743
>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
Length = 748
Score = 43.5 bits (101), Expect = 5e-04
Identities = 62/233 (26%), Positives = 85/233 (36%), Gaps = 36/233 (15%)
Query: 148 QAQALARQQALQHAQTLAHAPPQTLQHPQGIPPPQALSHPQSLQQPQGLGHPQ------- 200
Q Q +QQALQ AQ PP +Q PQ PP + + PQ LQQ H Q
Sbjct: 254 QQQQQQQQQALQ-AQPPIQQPP--MQQPQ---PPPSQALPQQLQQMHHTQHHQPPPQPQQ 307
Query: 201 ------------PMAQTQGLV-HPQALAHQGL-QHPHNPLLHGGRKMPDSDAPPNVTVST 246
P +QTQ LV QAL Q L P + + P V
Sbjct: 308 PPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQ 367
Query: 247 STIPLSMAATL-------QHSQPPDLSSIVHQINQFCQTRAGISTTSVCEGQIANPSPIS 299
+ + + AA + S P LSS Q QT + Q PS
Sbjct: 368 TAVQTAQAAQMVAPGVQVSQSSLPMLSS--PSPGQQVQTPQSMPPPPQPSPQPGQPSSQP 425
Query: 300 RSLLINASTRVSTHSVPTPMPSCVVNPMEHTHAATAALPAAGPVNLPTGISRV 352
S + + + +P+P P +P+ ++P+ GP+N P S V
Sbjct: 426 NSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSV 478
Score = 32.7 bits (73), Expect = 0.91
Identities = 57/235 (24%), Positives = 87/235 (37%), Gaps = 26/235 (11%)
Query: 148 QAQALARQQALQHAQTLAHAPPQTLQHPQGIPPPQALSHPQSLQQPQGLGHPQP------ 201
Q Q +QQ LQ L Q Q Q QAL +QQP + PQP
Sbjct: 228 QQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPP-MQQPQPPPSQAL 286
Query: 202 MAQTQGLVHPQALAHQGLQHPHNPLLHGGRKMPDSDAPPNVTVSTSTIPLSMAATLQHSQ 261
Q Q + H Q HQ P P + + P P + T + ++ + ++Q
Sbjct: 287 PQQLQQMHHTQ--HHQPPPQPQQPPV--AQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQ 342
Query: 262 PP----DLSSIVHQ---INQFCQTRAGISTTSVCEGQIANPSPISRSLLINAST-----R 309
PP +V Q Q Q + + T + +A +S+S L S+ +
Sbjct: 343 PPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQ-MVAPGVQVSQSSLPMLSSPSPGQQ 401
Query: 310 VSTHSVPTPMPSCVVNPMEHTHAATAALPAAGPVNLPTGISRVPTGYPSDLKPVT 364
V T P P P + + + + ++GP P+ P+ PS PVT
Sbjct: 402 VQTPQSMPPPPQPSPQPGQPSSQPNSNV-SSGPAPSPSSFLPSPSPQPSQ-SPVT 454
>gi|157743257 POU domain, class 6, transcription factor 2 [Homo
sapiens]
Length = 691
Score = 43.1 bits (100), Expect = 7e-04
Identities = 52/201 (25%), Positives = 78/201 (38%), Gaps = 23/201 (11%)
Query: 135 PYATVAPSTLAHPQAQALARQQALQHAQTLAHAPPQTLQHPQGIPPPQALSHPQSLQQPQ 194
P + ++ + Q Q L Q Q Q PP T QHPQ P PQA S QS QQP
Sbjct: 165 PLQNLQATSSLNSQLQQLQLQLQQQQQQQQQQPPPSTNQHPQ--PAPQAPS--QSQQQPL 220
Query: 195 GLGHPQ--PMAQTQGLVHPQALAHQGLQHPHNPLLHGGRKMPDSDAPPNVTVSTSTIPLS 252
PQ P A Q P A Q LQ P H + P+ T +S+ P
Sbjct: 221 QPTPPQQPPPASQQ----PPAPTSQ-LQQAPQPQQHQPHSHSQNQNQPSPTQQSSSPPQK 275
Query: 253 MAATLQHSQPPDL----------SSIVHQINQFCQTRAGISTTSVCEGQIANPSPISRSL 302
+ + H P L + + Q + I+++ +++ ++ L
Sbjct: 276 PSQSPGHGLPSPLTPPNPLQLVNNPLASQAAAAAAAMSSIASSQAFGNALSSLQGVTGQL 335
Query: 303 LINASTRV--STHSVPTPMPS 321
+ NA ++ + +P P PS
Sbjct: 336 VTNAQGQIIGTIPLMPNPGPS 356
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 42.7 bits (99), Expect = 9e-04
Identities = 88/376 (23%), Positives = 121/376 (32%), Gaps = 90/376 (23%)
Query: 131 PPVAPYATVAPSTLAHPQAQALARQQALQHAQTLAHAPPQTLQHPQGIPPPQALSHPQ-- 188
P P AT P + +QA + QA H HPQ P P HP
Sbjct: 210 PGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPH 269
Query: 189 --------SLQQPQGLGHPQPMAQTQGLVHPQAL-AHQGLQHPHNPLLHGGRKMPDSDAP 239
S QP H QP QG P +L A LQHP P G +P +
Sbjct: 270 PPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFG---LPPQASQ 326
Query: 240 PNVTVSTS----------TIPLSMAATLQHSQPPDLSSIVHQINQFCQTRAGISTTSVCE 289
+ TS +P S +A LQ QPP + + TT + +
Sbjct: 327 GQAPLGTSPAAAYPHTSLQLPASQSA-LQSQQPPREQPLPPAPLAMPHIKPP-PTTPIPQ 384
Query: 290 ----------GQIANPSPISRSL------LINASTRVSTHSVPT-------------PMP 320
++ PSP S + + + +STH P+ P+P
Sbjct: 385 LPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLP 444
Query: 321 SCVVNPMEHTHAATAALPAAGPVNLPTGISRVP-----------TGYPSDLKPVTWNQHQ 369
S P T + P A + PTG+ +V G P + P T
Sbjct: 445 SSPAQPPGLTQSQNLPPPPAS--HPPTGLHQVAPQPPFAQHPFVPGGPPPITPPT----- 497
Query: 370 LAHLQQMCSEASGTPA-------PGLTGKHAAGRELAGPGFVGKAPAYPQELCLAQSFHL 422
C S PA P +G A+G +AG +E L +
Sbjct: 498 -------CPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEP 550
Query: 423 K---PPLEKPTPSPPV 435
+ PP P+P P V
Sbjct: 551 ESPPPPPRSPSPEPTV 566
Score = 39.3 bits (90), Expect = 0.010
Identities = 53/202 (26%), Positives = 72/202 (35%), Gaps = 32/202 (15%)
Query: 84 SAQRYSPYPTQAATKAGLLAIVKVPAKSILKDFDGTRARLLPEA------IMNPPVAPYA 137
++Q +P T A ++ ++S L+ R + LP A I PP P
Sbjct: 324 ASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIP 383
Query: 138 TVAPSTLAHPQAQALARQQALQHAQTLAHAPPQTLQ--------HPQGIPPPQALSHPQS 189
+ P+ AH L+ L PP L+ HP PP PQS
Sbjct: 384 QL-PAPQAHKHPPHLSGPSPFSMNANLP--PPPALKPLSSLSTHHPPSAHPPPLQLMPQS 440
Query: 190 LQQPQGLGHPQPMAQTQGL-----VHPQALAHQGLQHP---HNPLLHGGRKMPDSDAPPN 241
P P + Q+Q L HP HQ P +P + GG P PP
Sbjct: 441 QPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGG---PPPITPPT 497
Query: 242 VTVSTSTIPLSMAATLQHSQPP 263
STST P + +QPP
Sbjct: 498 CP-STSTPPAGPGTS---AQPP 515
Score = 34.7 bits (78), Expect = 0.24
Identities = 95/382 (24%), Positives = 121/382 (31%), Gaps = 62/382 (16%)
Query: 148 QAQALARQQALQHAQTLAHAPPQTLQHPQGIPPPQALSHP--------QSLQQPQGLGHP 199
QAQ A Q + APP T Q P P P A + P Q+ QPQ P
Sbjct: 181 QAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAP 240
Query: 200 QPMAQTQ--GLVHPQ------ALAHQGLQHPHNPLL-HGGRKMPDSDAPPNVTVSTSTIP 250
P Q +HPQ H P PL G+ S A P + P
Sbjct: 241 VPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGP 300
Query: 251 LSMAA--TLQHSQPPDLSSIVHQINQFCQTRAGISTTSVCEGQIANPSPISRSLL----- 303
S+ A LQH PP + Q +Q Q G S + + P S+S L
Sbjct: 301 HSLQAGPLLQHPGPPQPFGLPPQASQ-GQAPLGTSPAAAYP-HTSLQLPASQSALQSQQP 358
Query: 304 -----INASTRVSTHSVPTPMPSCVVNPMEHTHAATAALPAAGPVNLPTGISRVPTGYPS 358
+ + H P P P H L P ++ + P P
Sbjct: 359 PREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKP- 417
Query: 359 DLKPVTWNQHQLAHLQQMCSEASGTPAPGLTGKHAAGRELAGPGFVGKAPAYPQELCLAQ 418
L ++ + AH + P P +PA P L Q
Sbjct: 418 -LSSLSTHHPPSAHPPPLQLMPQSQPLP-------------------SSPAQPPG--LTQ 455
Query: 419 SFHLKPPLEKPTPSPPVN-GMAAPLAYPNGHYFQPLWNNILPTPNSDSSGSQDLAMPFHG 477
S +L PP P PP AP H F P + TP + S S A P
Sbjct: 456 SQNLPPP---PASHPPTGLHQVAPQPPFAQHPFVPGGPPPI-TPPTCPSTSTPPAGPGTS 511
Query: 478 GQPTGAPLDCAAAPGAHYRAGT 499
QP P AAA G G+
Sbjct: 512 AQP---PCSGAAASGGSIAGGS 530
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 42.7 bits (99), Expect = 9e-04
Identities = 88/376 (23%), Positives = 121/376 (32%), Gaps = 90/376 (23%)
Query: 131 PPVAPYATVAPSTLAHPQAQALARQQALQHAQTLAHAPPQTLQHPQGIPPPQALSHPQ-- 188
P P AT P + +QA + QA H HPQ P P HP
Sbjct: 764 PGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPH 823
Query: 189 --------SLQQPQGLGHPQPMAQTQGLVHPQAL-AHQGLQHPHNPLLHGGRKMPDSDAP 239
S QP H QP QG P +L A LQHP P G +P +
Sbjct: 824 PPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFG---LPPQASQ 880
Query: 240 PNVTVSTS----------TIPLSMAATLQHSQPPDLSSIVHQINQFCQTRAGISTTSVCE 289
+ TS +P S +A LQ QPP + + TT + +
Sbjct: 881 GQAPLGTSPAAAYPHTSLQLPASQSA-LQSQQPPREQPLPPAPLAMPHIKPP-PTTPIPQ 938
Query: 290 ----------GQIANPSPISRSL------LINASTRVSTHSVPT-------------PMP 320
++ PSP S + + + +STH P+ P+P
Sbjct: 939 LPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLP 998
Query: 321 SCVVNPMEHTHAATAALPAAGPVNLPTGISRVP-----------TGYPSDLKPVTWNQHQ 369
S P T + P A + PTG+ +V G P + P T
Sbjct: 999 SSPAQPPGLTQSQNLPPPPAS--HPPTGLHQVAPQPPFAQHPFVPGGPPPITPPT----- 1051
Query: 370 LAHLQQMCSEASGTPA-------PGLTGKHAAGRELAGPGFVGKAPAYPQELCLAQSFHL 422
C S PA P +G A+G +AG +E L +
Sbjct: 1052 -------CPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEP 1104
Query: 423 K---PPLEKPTPSPPV 435
+ PP P+P P V
Sbjct: 1105 ESPPPPPRSPSPEPTV 1120
Score = 39.3 bits (90), Expect = 0.010
Identities = 53/202 (26%), Positives = 72/202 (35%), Gaps = 32/202 (15%)
Query: 84 SAQRYSPYPTQAATKAGLLAIVKVPAKSILKDFDGTRARLLPEA------IMNPPVAPYA 137
++Q +P T A ++ ++S L+ R + LP A I PP P
Sbjct: 878 ASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIP 937
Query: 138 TVAPSTLAHPQAQALARQQALQHAQTLAHAPPQTLQ--------HPQGIPPPQALSHPQS 189
+ P+ AH L+ L PP L+ HP PP PQS
Sbjct: 938 QL-PAPQAHKHPPHLSGPSPFSMNANLP--PPPALKPLSSLSTHHPPSAHPPPLQLMPQS 994
Query: 190 LQQPQGLGHPQPMAQTQGL-----VHPQALAHQGLQHP---HNPLLHGGRKMPDSDAPPN 241
P P + Q+Q L HP HQ P +P + GG P PP
Sbjct: 995 QPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGG---PPPITPPT 1051
Query: 242 VTVSTSTIPLSMAATLQHSQPP 263
STST P + +QPP
Sbjct: 1052 CP-STSTPPAGPGTS---AQPP 1069
Score = 34.7 bits (78), Expect = 0.24
Identities = 95/382 (24%), Positives = 121/382 (31%), Gaps = 62/382 (16%)
Query: 148 QAQALARQQALQHAQTLAHAPPQTLQHPQGIPPPQALSHP--------QSLQQPQGLGHP 199
QAQ A Q + APP T Q P P P A + P Q+ QPQ P
Sbjct: 735 QAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAP 794
Query: 200 QPMAQTQ--GLVHPQ------ALAHQGLQHPHNPLL-HGGRKMPDSDAPPNVTVSTSTIP 250
P Q +HPQ H P PL G+ S A P + P
Sbjct: 795 VPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGP 854
Query: 251 LSMAA--TLQHSQPPDLSSIVHQINQFCQTRAGISTTSVCEGQIANPSPISRSLL----- 303
S+ A LQH PP + Q +Q Q G S + + P S+S L
Sbjct: 855 HSLQAGPLLQHPGPPQPFGLPPQASQ-GQAPLGTSPAAAYP-HTSLQLPASQSALQSQQP 912
Query: 304 -----INASTRVSTHSVPTPMPSCVVNPMEHTHAATAALPAAGPVNLPTGISRVPTGYPS 358
+ + H P P P H L P ++ + P P
Sbjct: 913 PREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKP- 971
Query: 359 DLKPVTWNQHQLAHLQQMCSEASGTPAPGLTGKHAAGRELAGPGFVGKAPAYPQELCLAQ 418
L ++ + AH + P P +PA P L Q
Sbjct: 972 -LSSLSTHHPPSAHPPPLQLMPQSQPLP-------------------SSPAQPPG--LTQ 1009
Query: 419 SFHLKPPLEKPTPSPPVN-GMAAPLAYPNGHYFQPLWNNILPTPNSDSSGSQDLAMPFHG 477
S +L PP P PP AP H F P + TP + S S A P
Sbjct: 1010 SQNLPPP---PASHPPTGLHQVAPQPPFAQHPFVPGGPPPI-TPPTCPSTSTPPAGPGTS 1065
Query: 478 GQPTGAPLDCAAAPGAHYRAGT 499
QP P AAA G G+
Sbjct: 1066 AQP---PCSGAAASGGSIAGGS 1084
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 42.7 bits (99), Expect = 9e-04
Identities = 88/376 (23%), Positives = 121/376 (32%), Gaps = 90/376 (23%)
Query: 131 PPVAPYATVAPSTLAHPQAQALARQQALQHAQTLAHAPPQTLQHPQGIPPPQALSHPQ-- 188
P P AT P + +QA + QA H HPQ P P HP
Sbjct: 764 PGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPH 823
Query: 189 --------SLQQPQGLGHPQPMAQTQGLVHPQAL-AHQGLQHPHNPLLHGGRKMPDSDAP 239
S QP H QP QG P +L A LQHP P G +P +
Sbjct: 824 PPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFG---LPPQASQ 880
Query: 240 PNVTVSTS----------TIPLSMAATLQHSQPPDLSSIVHQINQFCQTRAGISTTSVCE 289
+ TS +P S +A LQ QPP + + TT + +
Sbjct: 881 GQAPLGTSPAAAYPHTSLQLPASQSA-LQSQQPPREQPLPPAPLAMPHIKPP-PTTPIPQ 938
Query: 290 ----------GQIANPSPISRSL------LINASTRVSTHSVPT-------------PMP 320
++ PSP S + + + +STH P+ P+P
Sbjct: 939 LPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLP 998
Query: 321 SCVVNPMEHTHAATAALPAAGPVNLPTGISRVP-----------TGYPSDLKPVTWNQHQ 369
S P T + P A + PTG+ +V G P + P T
Sbjct: 999 SSPAQPPGLTQSQNLPPPPAS--HPPTGLHQVAPQPPFAQHPFVPGGPPPITPPT----- 1051
Query: 370 LAHLQQMCSEASGTPA-------PGLTGKHAAGRELAGPGFVGKAPAYPQELCLAQSFHL 422
C S PA P +G A+G +AG +E L +
Sbjct: 1052 -------CPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEP 1104
Query: 423 K---PPLEKPTPSPPV 435
+ PP P+P P V
Sbjct: 1105 ESPPPPPRSPSPEPTV 1120
Score = 39.3 bits (90), Expect = 0.010
Identities = 53/202 (26%), Positives = 72/202 (35%), Gaps = 32/202 (15%)
Query: 84 SAQRYSPYPTQAATKAGLLAIVKVPAKSILKDFDGTRARLLPEA------IMNPPVAPYA 137
++Q +P T A ++ ++S L+ R + LP A I PP P
Sbjct: 878 ASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIP 937
Query: 138 TVAPSTLAHPQAQALARQQALQHAQTLAHAPPQTLQ--------HPQGIPPPQALSHPQS 189
+ P+ AH L+ L PP L+ HP PP PQS
Sbjct: 938 QL-PAPQAHKHPPHLSGPSPFSMNANLP--PPPALKPLSSLSTHHPPSAHPPPLQLMPQS 994
Query: 190 LQQPQGLGHPQPMAQTQGL-----VHPQALAHQGLQHP---HNPLLHGGRKMPDSDAPPN 241
P P + Q+Q L HP HQ P +P + GG P PP
Sbjct: 995 QPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGG---PPPITPPT 1051
Query: 242 VTVSTSTIPLSMAATLQHSQPP 263
STST P + +QPP
Sbjct: 1052 CP-STSTPPAGPGTS---AQPP 1069
Score = 34.7 bits (78), Expect = 0.24
Identities = 95/382 (24%), Positives = 121/382 (31%), Gaps = 62/382 (16%)
Query: 148 QAQALARQQALQHAQTLAHAPPQTLQHPQGIPPPQALSHP--------QSLQQPQGLGHP 199
QAQ A Q + APP T Q P P P A + P Q+ QPQ P
Sbjct: 735 QAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAP 794
Query: 200 QPMAQTQ--GLVHPQ------ALAHQGLQHPHNPLL-HGGRKMPDSDAPPNVTVSTSTIP 250
P Q +HPQ H P PL G+ S A P + P
Sbjct: 795 VPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGP 854
Query: 251 LSMAA--TLQHSQPPDLSSIVHQINQFCQTRAGISTTSVCEGQIANPSPISRSLL----- 303
S+ A LQH PP + Q +Q Q G S + + P S+S L
Sbjct: 855 HSLQAGPLLQHPGPPQPFGLPPQASQ-GQAPLGTSPAAAYP-HTSLQLPASQSALQSQQP 912
Query: 304 -----INASTRVSTHSVPTPMPSCVVNPMEHTHAATAALPAAGPVNLPTGISRVPTGYPS 358
+ + H P P P H L P ++ + P P
Sbjct: 913 PREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKP- 971
Query: 359 DLKPVTWNQHQLAHLQQMCSEASGTPAPGLTGKHAAGRELAGPGFVGKAPAYPQELCLAQ 418
L ++ + AH + P P +PA P L Q
Sbjct: 972 -LSSLSTHHPPSAHPPPLQLMPQSQPLP-------------------SSPAQPPG--LTQ 1009
Query: 419 SFHLKPPLEKPTPSPPVN-GMAAPLAYPNGHYFQPLWNNILPTPNSDSSGSQDLAMPFHG 477
S +L PP P PP AP H F P + TP + S S A P
Sbjct: 1010 SQNLPPP---PASHPPTGLHQVAPQPPFAQHPFVPGGPPPI-TPPTCPSTSTPPAGPGTS 1065
Query: 478 GQPTGAPLDCAAAPGAHYRAGT 499
QP P AAA G G+
Sbjct: 1066 AQP---PCSGAAASGGSIAGGS 1084
>gi|54112403 chromodomain helicase DNA binding protein 7 [Homo
sapiens]
Length = 2997
Score = 42.0 bits (97), Expect = 0.001
Identities = 85/359 (23%), Positives = 134/359 (37%), Gaps = 72/359 (20%)
Query: 137 ATVAPSTLAHPQAQALARQQALQHAQTLAHAPPQTLQHPQGI---------PPPQALSHP 187
AT P L+H Q+ + +L+H+ H P T H + + PP Q P
Sbjct: 228 ATSGPGHLSHVPQQSPSMAPSLRHSVQQFHHHPSTALHGESVAHSPRFSPNPPQQGAVRP 287
Query: 188 QSLQ-QPQGLGHPQPMAQTQGLV--HPQALAHQGLQH--PHNPLLHGGRKMPDSDAPPNV 242
Q+L + P P G +P + +QGL + N L P + + P
Sbjct: 288 QTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRY 347
Query: 243 TVSTSTIPLSMAATLQHSQPPDLSSIVHQINQFCQTRAGISTTSVCEGQIANPSPIS--R 300
+ P + L H QP S ++Q+N QT S +G A+P P+S +
Sbjct: 348 PNAVG-FPSNSGQGLMHQQPIHPSGSLNQMN--TQT----MHPSQPQGTYASPPPMSPMK 400
Query: 301 SLLINAST---RVSTHSVPTPMPSCVVNPMEH---THAATAALPAA----GPVNLP---- 346
++ A T +V S PM M H +H A+ GP N+
Sbjct: 401 AMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQPPGAMGIGQRNMGPRNMQQSRP 460
Query: 347 -TGISRVPTGYPSDLKPVTWNQHQLAHLQQMCSEASGTPAPGLTGKHA-AGRELAGPGFV 404
G+S P ++P +G P GL A R + G
Sbjct: 461 FIGMSSAPRELTGHMRP------------------NGCPGVGLGDPQAIQERLIPGQQHP 502
Query: 405 GKAPAYPQELCLAQSFHLKPPLEKPTPSPPVNGMAAPLAYPNGHYFQPLWNNILPTPNS 463
G+ P++ Q PPL+ P P ++ ++P P+ H+ QP W + P+P +
Sbjct: 503 GQQPSF-------QQLPTCPPLQ---PHPGLHHQSSP---PHPHH-QP-WAQLHPSPQN 546
>gi|17864090 autism susceptibility candidate 2 isoform 1 [Homo
sapiens]
Length = 1259
Score = 42.0 bits (97), Expect = 0.001
Identities = 91/368 (24%), Positives = 125/368 (33%), Gaps = 59/368 (16%)
Query: 114 KDFDGTRARLLPEAIMNPPVAPYATVAPSTLAHPQAQALARQQAL-QHAQTLAHAPPQTL 172
K D + + ++ P A P PQ +A + L Q + PP +
Sbjct: 280 KSQDCCKEPIFEPVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLST 339
Query: 173 QHPQGIPPPQALSHPQSLQQPQGLGHPQPMAQTQGLVH---PQALAHQGLQHPHNPL--- 226
Q PQG PP+A P QPQ P+P + TQ L+H P AH Q PL
Sbjct: 340 QPPQG--PPEAQLQP--APQPQVQRPPRPQSPTQ-LLHQNLPPVQAHPSAQSLSQPLSAY 394
Query: 227 ---------LHGGRKMPDS---DAPPNVT--VSTSTIPLSMA-ATLQHSQPPDLS--SIV 269
L R + APP+++ S S PLS+ + HS P L +
Sbjct: 395 NSSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHS 454
Query: 270 HQINQFCQTRAGISTTSVCEGQIANPSPI-SRSLLINASTRVSTHSVPTPMPSCVVNPME 328
H N F A + P P+ S SL + ST+S + +
Sbjct: 455 HHPNMFAPPTA-----------LPPPPPLTSGSLQVAGHPAGSTYSEQDILRQELNTRFL 503
Query: 329 HTHAATAALPAAGPVNLPTGISRVPTGYPSDLKPVTWNQHQLAHLQQMCSEASGTPAPGL 388
+ +A P L T + +QHQ H Q + + TP P
Sbjct: 504 ASQSADRGASLGPPPYLRTEFHQ--------------HQHQHQHTHQHTHQHTFTPFPHA 549
Query: 389 TGKHAAGRELAGPGFVGKAPAYPQELCLAQSFHLKPPLEKPTPSPPVNGMAAPLAYPNGH 448
A A P F K P FH PP + PP+ P G
Sbjct: 550 IPPTAIMPTPAPPMF-DKYPTKVDPFYRHSLFHSYPP--AVSGIPPMIPPTGPFGSLQG- 605
Query: 449 YFQPLWNN 456
FQP +N
Sbjct: 606 AFQPKTSN 613
>gi|91176325 bromodomain adjacent to zinc finger domain, 2A [Homo
sapiens]
Length = 1905
Score = 42.0 bits (97), Expect = 0.001
Identities = 70/305 (22%), Positives = 105/305 (34%), Gaps = 56/305 (18%)
Query: 117 DGTRARLLPEAIMNPPVAPYATVAPSTLAHPQAQALARQQALQHAQTLAHAPPQTLQHPQ 176
+GT L+PE ++ A ++L + + L + T A +P + P+
Sbjct: 1137 EGTEGNLVPEEVIKKETDSLKVAAHASL---NPALFSMKMELAGSNTTASSPARARGRPR 1193
Query: 177 GIPP----PQALSHP---QSLQQPQGLGHPQPM----AQTQGLVHPQALAHQGLQHPHNP 225
P P+ L P Q +QPQ P+ AQ Q + Q +H+G
Sbjct: 1194 KTKPGSMQPRHLKSPVRGQDSEQPQAQLQPEAQLHAPAQPQPQLQLQLQSHKGFLEQEGS 1253
Query: 226 LLHGGRKMPDSDAPPNVTVSTSTIPLSMAATLQHSQPPDLSSIVHQINQFCQTRAGISTT 285
L G+ D +S S ++ T HS S + + A
Sbjct: 1254 PLSLGQSQHD--------LSQSAFLSWLSQTQSHSSLLSSSVLTPDSSPGKLDPAPSQPP 1305
Query: 286 SVCEGQIANPSPISRSLLINASTRVSTHSVPTPMPSCVVNPMEHTHAATAALPAAGPVNL 345
E A SP ++L N S ++ ++ PTP P A + P P L
Sbjct: 1306 EEPEPDEAESSPDPQALWFNISAQMPCNAAPTPPP-----------AVSEDQPTPSPQQL 1354
Query: 346 PTGISRVPTGYPSDLKPVTWNQHQLAHLQQMCS--EASGTPAPGLTGKHAAGRELAGPGF 403
S P PS P CS + S TP GL K AG PG
Sbjct: 1355 ---ASSKPMNRPSAANP--------------CSPVQFSSTPLAGLAPKRRAG----DPGE 1393
Query: 404 VGKAP 408
+ ++P
Sbjct: 1394 MPQSP 1398
Score = 30.0 bits (66), Expect = 5.9
Identities = 31/121 (25%), Positives = 48/121 (39%), Gaps = 11/121 (9%)
Query: 82 DTSAQRYSPYPTQAATKAGLLAIVKVPAKSILKDFDGTRARLLPEAIMNPPVAPYATVAP 141
D S + + +Q + + LL+ S+L D + +L P A PP P A
Sbjct: 1263 DLSQSAFLSWLSQTQSHSSLLS------SSVLTP-DSSPGKLDP-APSQPPEEPEPDEAE 1314
Query: 142 STLAHPQAQALARQQALQHAQTLAHAPPQTLQHPQGIPPPQALSHPQSLQQPQGLGHPQP 201
S+ P QAL + Q A PP + Q P PQ L+ + + +P P
Sbjct: 1315 SS---PDPQALWFNISAQMPCNAAPTPPPAVSEDQPTPSPQQLASSKPMNRPSAANPCSP 1371
Query: 202 M 202
+
Sbjct: 1372 V 1372
>gi|239745032 PREDICTED: hypothetical protein XP_002343336 [Homo
sapiens]
Length = 828
Score = 41.6 bits (96), Expect = 0.002
Identities = 50/223 (22%), Positives = 74/223 (33%), Gaps = 18/223 (8%)
Query: 125 PEAIMNPPVAPYATVAPSTLAHPQAQALARQQALQHAQTLAHAPPQTLQHPQGIPPPQAL 184
P +PP+ P+ HP L H P + HP PP +
Sbjct: 56 PSIHTHPPIHPHTHPPIHPPTHPSIHPLIHPSI----HPSLHPPTHSSIHPSTHPPTHSS 111
Query: 185 SHPQSLQQPQGLGHPQPMAQTQGLVHPQALAHQGLQHPHNPLLHGGRKMPDSDAPPNVTV 244
HP L HP T +HP +H +P +H P + +P + ++
Sbjct: 112 IHPSIHPSTHPLIHPSIHPSTHSSIHPPTHSHPSTHPLIHPSIH-----PPTHSPIHPSI 166
Query: 245 STSTIPLSMAATLQHSQPPDLSSIVHQINQFCQTRAGISTTSVCE---GQIANPSPISRS 301
T P + + P SSI + F T S +PS S +
Sbjct: 167 HPPTHPPTHPSIHSSIHLPTHSSIHPPTHSFIHPSIHPPTHSPIHPLTHPFIHPSDSSAA 226
Query: 302 LLINA----STRVSTHSVPT--PMPSCVVNPMEHTHAATAALP 338
TR+S H PT P+ + +P H+ ALP
Sbjct: 227 SAGGVGPALQTRMSGHPRPTGSPVLALASHPPWHSLEVYRALP 269
Score = 37.0 bits (84), Expect = 0.048
Identities = 55/244 (22%), Positives = 83/244 (34%), Gaps = 34/244 (13%)
Query: 126 EAIMNPPVAPYATVAPSTLAHPQAQALARQQALQHAQTLAHAPPQTLQHPQGIPP--PQA 183
EA++ V+P + HP + + ++ H P HP PP P
Sbjct: 6 EALLVLAVSPPGKICIHPPLHPPTHSPSIHPSI-------HPPTHPSIHPSIHPPTHPSI 58
Query: 184 LSHPQSLQQPQGLGHPQPMAQTQGLVHPQALAHQGLQHPHNPLLHGGRKMPDSDAPPNVT 243
+HP HP L+HP H L P + +H P + P + +
Sbjct: 59 HTHPPIHPHTHPPIHPPTHPSIHPLIHPSI--HPSLHPPTHSSIH-----PSTHPPTHSS 111
Query: 244 VSTSTIPLSMAATLQHSQPPDLSSIVHQINQFCQTRAGISTTSVCEGQIANP--SPISRS 301
+ S P S + S P S +H T + ST + I P SPI S
Sbjct: 112 IHPSIHP-STHPLIHPSIHPSTHSSIHP-----PTHSHPSTHPLIHPSIHPPTHSPIHPS 165
Query: 302 L----------LINASTRVSTHSVPTPMPSCVVNPMEHTHAATAALPAAGPVNLPTGISR 351
+ I++S + THS P ++P H + P P P+ S
Sbjct: 166 IHPPTHPPTHPSIHSSIHLPTHSSIHPPTHSFIHPSIHPPTHSPIHPLTHPFIHPSDSSA 225
Query: 352 VPTG 355
G
Sbjct: 226 ASAG 229
>gi|83977459 pleckstrin homology-like domain, family A, member 1
[Homo sapiens]
Length = 401
Score = 41.6 bits (96), Expect = 0.002
Identities = 29/71 (40%), Positives = 32/71 (45%), Gaps = 8/71 (11%)
Query: 154 RQQALQHAQTLAHAPPQTLQHPQGIPPPQALSHPQSLQQPQGLGHPQPMAQTQGLVHPQA 213
+QQ L Q + PQ PQ P PQ PQS QPQ PQP Q Q L HP
Sbjct: 298 KQQHLVQQQPPSQPQPQPQLQPQPQPQPQPQPQPQSQPQPQ----PQPKPQPQQL-HPYP 352
Query: 214 LAHQGLQHPHN 224
H HPH+
Sbjct: 353 HPH---PHPHS 360
Score = 40.4 bits (93), Expect = 0.004
Identities = 24/83 (28%), Positives = 30/83 (36%), Gaps = 5/83 (6%)
Query: 125 PEAIMNPPVAPYATVAPSTLAHPQAQALARQQALQHAQTLAHAPPQTLQHPQGIPPPQAL 184
P+ + P P P + PQ Q + Q Q H P HP P P
Sbjct: 313 PQPQLQPQPQPQPQPQPQPQSQPQPQPQPKPQP-QQLHPYPHPHPHPHSHPHSHPHPHPH 371
Query: 185 SHPQSLQQPQGLGHPQPMAQTQG 207
HP + P HPQP +Q G
Sbjct: 372 PHPHQIPHP----HPQPHSQPHG 390
Score = 37.4 bits (85), Expect = 0.037
Identities = 31/123 (25%), Positives = 41/123 (33%), Gaps = 1/123 (0%)
Query: 102 LAIVKVPAKSILKDFDGTRARLLPEAIMNPPVAPYATVAPSTLAHPQAQALARQQALQHA 161
L +V+ + + TR + PP P PQ Q + Q+
Sbjct: 278 LQMVQYKNRQAILAVKSTRQKQQHLVQQQPPSQPQPQPQLQPQPQPQPQPQPQPQSQPQP 337
Query: 162 QTLAHAPPQTLQHPQGIPPPQALSHPQSLQQPQGLGHPQPMAQTQGLVHPQALAHQGLQH 221
Q PQ L HP P P SHP S P HP + H Q H+ L+
Sbjct: 338 QPQPKPQPQQL-HPYPHPHPHPHSHPHSHPHPHPHPHPHQIPHPHPQPHSQPHGHRLLRS 396
Query: 222 PHN 224
N
Sbjct: 397 TSN 399
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 41.2 bits (95), Expect = 0.003
Identities = 85/364 (23%), Positives = 116/364 (31%), Gaps = 57/364 (15%)
Query: 122 RLLPEAIMNPPVAPYATVAPSTLAHPQAQALAR--QQALQHAQTLAHAPPQTLQHP--QG 177
RLL + +P P +T A ST AHP QQ Q Q Q QH G
Sbjct: 450 RLLANSNAHPGPFPPSTGAQST-AHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSG 508
Query: 178 IPPPQALSHPQSLQQPQGLGHPQPMAQTQGLVHPQALAHQGLQHPHNPLLH--GGRKMPD 235
PPP A HP HP M+ + G + P L PH+ + + G P
Sbjct: 509 PPPPGAFPHPLEGGSSHH-AHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPP 567
Query: 236 SDAPPNVTVSTSTIPLSMAATLQHSQPPDLSSIVHQINQFCQTRAGISTTSVCEGQIANP 295
+ N + STS + P + + A +ST
Sbjct: 568 VSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVI--------- 618
Query: 296 SPISRSLLINASTRVSTHSVPTPMPSCVVNPMEHTHAATAALPAAGPVNLPTGISRVPTG 355
+ + ++ T S P P P P + TA P P + P+ + P G
Sbjct: 619 -----ATVASSPAGYKTASPPGPPPYGKRAPSPGAY-KTATPPGYKPGSPPSFRTGTPPG 672
Query: 356 YPSDLKPVTWNQHQLAHLQQMCSEASGTPAPGLTGKHAAGRELAGPGFVGKAPAYPQELC 415
Y GT P G G GPG + PA P L
Sbjct: 673 Y------------------------RGTSPPAGPGTFKPGSPTVGPGPL--PPAGPSGLP 706
Query: 416 LAQSFHLKPPLEKPTPSPPVNGMAAPLAYPNGHYFQPLWNNILPTPNSDSSGSQDLAMPF 475
L PP P PP++ P Y P + +P S S + + +P
Sbjct: 707 -----SLPPPPAAPASGPPLSATQIK-QEPAEEYETP--ESPVPPARSPSPPPKVVDVPS 758
Query: 476 HGGQ 479
H Q
Sbjct: 759 HASQ 762
Score = 40.8 bits (94), Expect = 0.003
Identities = 76/367 (20%), Positives = 120/367 (32%), Gaps = 62/367 (16%)
Query: 147 PQAQALARQQALQHAQTLAHAPPQTLQHPQGIPPPQALSHPQSLQ----QPQGLGHPQPM 202
P+ R + + +++ P+ + Q +P PQ+ S SL G P+ +
Sbjct: 65 PKVNKQGRSEEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDI 124
Query: 203 AQTQGLVHPQALA--------------HQGLQHPHNP--LLHGGRKMPDS---------D 237
Q P + QG P++P L + PDS +
Sbjct: 125 DQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFE 184
Query: 238 APPNVTVSTSTIPLSMAATLQHSQPPDLSSIVHQINQFCQTRAGISTTSVCEGQIANPSP 297
P+VT + P+ + PP Q+ T V G P
Sbjct: 185 PHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPG-------GTGGVLSGPPMGPKG 237
Query: 298 ISRSLLINASTRVSTHSVPTPMPSCVVNPMEHTHAATAALPAAGPVNLPTGISRVPTGYP 357
+ + H PT P+ + + + P P P G +P+ P
Sbjct: 238 GGAASSVGGPNGGKQHPPPT-------TPISVSSSGASGAPPTKPPTTPVGGGNLPSAPP 290
Query: 358 -SDLKPVTWNQHQLAHLQQMCSEASGTPAPGLTGK----HAAGRELAGPGFVGKAPAYPQ 412
++ VT N L+ + + AS +P PGL + H G G G P +
Sbjct: 291 PANFPHVTPNLPPPPALRPL-NNASASP-PGLGAQPLPGHLPSPHAMGQGMGGLPPGPEK 348
Query: 413 ELCLAQSFHLKPPLEKPTPSPPVNGMAAPLAYPNGHYFQPLWNNILPTPNSDSSGSQDLA 472
LA S H PP P+PP+ Y + ++ +S SS S A
Sbjct: 349 GPTLAPSPHSLPPASSSAPAPPMR-----FPYSSS-------SSSSAAASSSSSSSSSSA 396
Query: 473 MPFHGGQ 479
PF Q
Sbjct: 397 SPFPASQ 403
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 41.2 bits (95), Expect = 0.003
Identities = 85/364 (23%), Positives = 116/364 (31%), Gaps = 57/364 (15%)
Query: 122 RLLPEAIMNPPVAPYATVAPSTLAHPQAQALAR--QQALQHAQTLAHAPPQTLQHP--QG 177
RLL + +P P +T A ST AHP QQ Q Q Q QH G
Sbjct: 450 RLLANSNAHPGPFPPSTGAQST-AHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSG 508
Query: 178 IPPPQALSHPQSLQQPQGLGHPQPMAQTQGLVHPQALAHQGLQHPHNPLLH--GGRKMPD 235
PPP A HP HP M+ + G + P L PH+ + + G P
Sbjct: 509 PPPPGAFPHPLEGGSSHH-AHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPP 567
Query: 236 SDAPPNVTVSTSTIPLSMAATLQHSQPPDLSSIVHQINQFCQTRAGISTTSVCEGQIANP 295
+ N + STS + P + + A +ST
Sbjct: 568 VSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVI--------- 618
Query: 296 SPISRSLLINASTRVSTHSVPTPMPSCVVNPMEHTHAATAALPAAGPVNLPTGISRVPTG 355
+ + ++ T S P P P P + TA P P + P+ + P G
Sbjct: 619 -----ATVASSPAGYKTASPPGPPPYGKRAPSPGAY-KTATPPGYKPGSPPSFRTGTPPG 672
Query: 356 YPSDLKPVTWNQHQLAHLQQMCSEASGTPAPGLTGKHAAGRELAGPGFVGKAPAYPQELC 415
Y GT P G G GPG + PA P L
Sbjct: 673 Y------------------------RGTSPPAGPGTFKPGSPTVGPGPL--PPAGPSGLP 706
Query: 416 LAQSFHLKPPLEKPTPSPPVNGMAAPLAYPNGHYFQPLWNNILPTPNSDSSGSQDLAMPF 475
L PP P PP++ P Y P + +P S S + + +P
Sbjct: 707 -----SLPPPPAAPASGPPLSATQIK-QEPAEEYETP--ESPVPPARSPSPPPKVVDVPS 758
Query: 476 HGGQ 479
H Q
Sbjct: 759 HASQ 762
Score = 40.8 bits (94), Expect = 0.003
Identities = 76/367 (20%), Positives = 120/367 (32%), Gaps = 62/367 (16%)
Query: 147 PQAQALARQQALQHAQTLAHAPPQTLQHPQGIPPPQALSHPQSLQ----QPQGLGHPQPM 202
P+ R + + +++ P+ + Q +P PQ+ S SL G P+ +
Sbjct: 65 PKVNKQGRSEEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDI 124
Query: 203 AQTQGLVHPQALA--------------HQGLQHPHNP--LLHGGRKMPDS---------D 237
Q P + QG P++P L + PDS +
Sbjct: 125 DQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFE 184
Query: 238 APPNVTVSTSTIPLSMAATLQHSQPPDLSSIVHQINQFCQTRAGISTTSVCEGQIANPSP 297
P+VT + P+ + PP Q+ T V G P
Sbjct: 185 PHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPG-------GTGGVLSGPPMGPKG 237
Query: 298 ISRSLLINASTRVSTHSVPTPMPSCVVNPMEHTHAATAALPAAGPVNLPTGISRVPTGYP 357
+ + H PT P+ + + + P P P G +P+ P
Sbjct: 238 GGAASSVGGPNGGKQHPPPT-------TPISVSSSGASGAPPTKPPTTPVGGGNLPSAPP 290
Query: 358 -SDLKPVTWNQHQLAHLQQMCSEASGTPAPGLTGK----HAAGRELAGPGFVGKAPAYPQ 412
++ VT N L+ + + AS +P PGL + H G G G P +
Sbjct: 291 PANFPHVTPNLPPPPALRPL-NNASASP-PGLGAQPLPGHLPSPHAMGQGMGGLPPGPEK 348
Query: 413 ELCLAQSFHLKPPLEKPTPSPPVNGMAAPLAYPNGHYFQPLWNNILPTPNSDSSGSQDLA 472
LA S H PP P+PP+ Y + ++ +S SS S A
Sbjct: 349 GPTLAPSPHSLPPASSSAPAPPMR-----FPYSSS-------SSSSAAASSSSSSSSSSA 396
Query: 473 MPFHGGQ 479
PF Q
Sbjct: 397 SPFPASQ 403
>gi|83776598 virus-induced signaling adapter [Homo sapiens]
Length = 540
Score = 40.8 bits (94), Expect = 0.003
Identities = 53/239 (22%), Positives = 89/239 (37%), Gaps = 53/239 (22%)
Query: 168 PPQTLQHPQ------GIPPPQAL-SHPQSLQQPQGLGHPQPMAQTQGLVHPQALAHQGLQ 220
PP L+ P G P P A S P + + + +P P+ +TQ P + Q LQ
Sbjct: 103 PPDPLEPPSLPAERPGPPTPAAAHSIPYNSCREKEPSYPMPVQETQAPESPGENSEQALQ 162
Query: 221 H------PHNP----------------LLHGGRKMPDSDAPPN---------------VT 243
P NP L G + D++ V+
Sbjct: 163 TLSPRAIPRNPDGGPLESSSDLAALSPLTSSGHQEQDTELGSTHTAGATSSLTPSRGPVS 222
Query: 244 VSTSTIPLSMAATLQHSQPPDLSSIVHQINQFCQTRAGISTTSVCEGQIANPSPISRSLL 303
S S PL+ + P S+V F + G+++ EG+ S + ++
Sbjct: 223 PSVSFQPLARSTPRASRLPGPTGSVVSTGTSFSSSSPGLASAGAAEGKQGAESDQAEPII 282
Query: 304 INASTRVSTHSVPTPMPSCVVNPMEHTHAATAALPAAGPVNLPTGISRVPTGYPSDLKP 362
++ +S+P+ +P+ ++ P+ T AL P N P +S VP+ P+ KP
Sbjct: 283 CSSGAEAPANSLPSKVPTTLM-PVN-----TVALKV--PAN-PASVSTVPSKLPTSSKP 332
>gi|187829452 autism susceptibility candidate 2 isoform 2 [Homo
sapiens]
Length = 1235
Score = 40.8 bits (94), Expect = 0.003
Identities = 84/343 (24%), Positives = 115/343 (33%), Gaps = 56/343 (16%)
Query: 114 KDFDGTRARLLPEAIMNPPVAPYATVAPSTLAHPQAQALARQQAL-QHAQTLAHAPPQTL 172
K D + + ++ P A P PQ +A + L Q + PP +
Sbjct: 280 KSQDCCKEPIFEPVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLST 339
Query: 173 QHPQGIPPPQALSHPQSLQQPQGLGHPQPMAQTQGLVH---PQALAHQGLQHPHNPL--- 226
Q PQG PP+A P QPQ P+P + TQ L+H P AH Q PL
Sbjct: 340 QPPQG--PPEAQLQP--APQPQVQRPPRPQSPTQ-LLHQNLPPVQAHPSAQSLSQPLSAY 394
Query: 227 ---------LHGGRKMPDS---DAPPNVT--VSTSTIPLSMA-ATLQHSQPPDLS--SIV 269
L R + APP+++ S S PLS+ + HS P L +
Sbjct: 395 NSSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHS 454
Query: 270 HQINQFCQTRAGISTTSVCEGQIANPSPI-SRSLLINASTRVSTHSVPTPMPSCVVNPME 328
H N F A + P P+ S SL + ST+S + +
Sbjct: 455 HHPNMFAPPTA-----------LPPPPPLTSGSLQVAGHPAGSTYSEQDILRQELNTRFL 503
Query: 329 HTHAATAALPAAGPVNLPTGISRVPTGYPSDLKPVTWNQHQLAHLQQMCSEASGTPAPGL 388
+ +A P L T + +QHQ H Q + + TP P
Sbjct: 504 ASQSADRGASLGPPPYLRTEFHQ--------------HQHQHQHTHQHTHQHTFTPFPHA 549
Query: 389 TGKHAAGRELAGPGFVGKAPAYPQELCLAQSFHLKPPLEKPTP 431
A A P F K P FH PP P
Sbjct: 550 IPPTAIMPTPAPPMF-DKYPTKVDPFYRHSLFHSYPPAVSGIP 591
>gi|149158696 HLA-B associated transcript-3 isoform b [Homo sapiens]
Length = 1126
Score = 40.8 bits (94), Expect = 0.003
Identities = 89/373 (23%), Positives = 128/373 (34%), Gaps = 94/373 (25%)
Query: 89 SPYPTQAATKAGLLAIVKVPAKSILKDFDGTRARLLPEAIMNPPVAPYAT-VAPSTLAHP 147
S Y T + + I ++ +GTR P A PP A+ VAPS+
Sbjct: 356 SHYTTPMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAPPPGPGQASSVAPSST--- 412
Query: 148 QAQALARQQALQHAQTLAHAPPQTLQHPQGIPPPQALSHPQSLQQPQGLGHPQPMAQTQG 207
+ ++ A P P G PP A SHP+ ++ + H
Sbjct: 413 ------------NVESSAEGAP-----PPGPAPPPATSHPRVIR----ISHQS------- 444
Query: 208 LVHPQALAHQGLQH--------------PHNPLLHG---GRKMPD-SDAPPNVTVSTSTI 249
V P + H +Q P P HG G+++P AP V ++ T
Sbjct: 445 -VEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQTLGQQVPGFPTAPTRVVIARPTP 503
Query: 250 PLSMAATLQHSQPPDLSSIVHQINQFCQTRAGISTTSVCEGQIAN--PSPISRSLLINAS 307
P A H P +S + AG+ T + ++ + + +L+
Sbjct: 504 P---QARPSHPGGPPVSGTLQ--------GAGLGTNASLAQMVSGLVGQLLMQPVLVAQG 552
Query: 308 TRVSTHSVPTPMPSCVVNPMEHTHAATAALPA-AGPVNLPTGISRVPTGYPSDLKPVTWN 366
T P P P+ T+ AT A PA GP P PT PS
Sbjct: 553 T---PGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPP------PTPQPS-------- 595
Query: 367 QHQLAHLQ--QMCSEASGTPAPGLTGKHAAGREL--AGPGFVGKAPAYPQELC-LAQSFH 421
+A LQ Q+ G PG G A + A PG PA+ Q + Q+
Sbjct: 596 ---MADLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPG----VPAFLQGMTDFLQATQ 648
Query: 422 LKPPLEKPTPSPP 434
PP P P PP
Sbjct: 649 TAPPPPPPPPPPP 661
>gi|18375632 HLA-B associated transcript-3 isoform b [Homo sapiens]
Length = 1126
Score = 40.8 bits (94), Expect = 0.003
Identities = 89/373 (23%), Positives = 128/373 (34%), Gaps = 94/373 (25%)
Query: 89 SPYPTQAATKAGLLAIVKVPAKSILKDFDGTRARLLPEAIMNPPVAPYAT-VAPSTLAHP 147
S Y T + + I ++ +GTR P A PP A+ VAPS+
Sbjct: 356 SHYTTPMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAPPPGPGQASSVAPSST--- 412
Query: 148 QAQALARQQALQHAQTLAHAPPQTLQHPQGIPPPQALSHPQSLQQPQGLGHPQPMAQTQG 207
+ ++ A P P G PP A SHP+ ++ + H
Sbjct: 413 ------------NVESSAEGAP-----PPGPAPPPATSHPRVIR----ISHQS------- 444
Query: 208 LVHPQALAHQGLQH--------------PHNPLLHG---GRKMPD-SDAPPNVTVSTSTI 249
V P + H +Q P P HG G+++P AP V ++ T
Sbjct: 445 -VEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQTLGQQVPGFPTAPTRVVIARPTP 503
Query: 250 PLSMAATLQHSQPPDLSSIVHQINQFCQTRAGISTTSVCEGQIAN--PSPISRSLLINAS 307
P A H P +S + AG+ T + ++ + + +L+
Sbjct: 504 P---QARPSHPGGPPVSGTLQ--------GAGLGTNASLAQMVSGLVGQLLMQPVLVAQG 552
Query: 308 TRVSTHSVPTPMPSCVVNPMEHTHAATAALPA-AGPVNLPTGISRVPTGYPSDLKPVTWN 366
T P P P+ T+ AT A PA GP P PT PS
Sbjct: 553 T---PGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPP------PTPQPS-------- 595
Query: 367 QHQLAHLQ--QMCSEASGTPAPGLTGKHAAGREL--AGPGFVGKAPAYPQELC-LAQSFH 421
+A LQ Q+ G PG G A + A PG PA+ Q + Q+
Sbjct: 596 ---MADLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPG----VPAFLQGMTDFLQATQ 648
Query: 422 LKPPLEKPTPSPP 434
PP P P PP
Sbjct: 649 TAPPPPPPPPPPP 661
>gi|18375630 HLA-B associated transcript-3 isoform b [Homo sapiens]
Length = 1126
Score = 40.8 bits (94), Expect = 0.003
Identities = 89/373 (23%), Positives = 128/373 (34%), Gaps = 94/373 (25%)
Query: 89 SPYPTQAATKAGLLAIVKVPAKSILKDFDGTRARLLPEAIMNPPVAPYAT-VAPSTLAHP 147
S Y T + + I ++ +GTR P A PP A+ VAPS+
Sbjct: 356 SHYTTPMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAPPPGPGQASSVAPSST--- 412
Query: 148 QAQALARQQALQHAQTLAHAPPQTLQHPQGIPPPQALSHPQSLQQPQGLGHPQPMAQTQG 207
+ ++ A P P G PP A SHP+ ++ + H
Sbjct: 413 ------------NVESSAEGAP-----PPGPAPPPATSHPRVIR----ISHQS------- 444
Query: 208 LVHPQALAHQGLQH--------------PHNPLLHG---GRKMPD-SDAPPNVTVSTSTI 249
V P + H +Q P P HG G+++P AP V ++ T
Sbjct: 445 -VEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQTLGQQVPGFPTAPTRVVIARPTP 503
Query: 250 PLSMAATLQHSQPPDLSSIVHQINQFCQTRAGISTTSVCEGQIAN--PSPISRSLLINAS 307
P A H P +S + AG+ T + ++ + + +L+
Sbjct: 504 P---QARPSHPGGPPVSGTLQ--------GAGLGTNASLAQMVSGLVGQLLMQPVLVAQG 552
Query: 308 TRVSTHSVPTPMPSCVVNPMEHTHAATAALPA-AGPVNLPTGISRVPTGYPSDLKPVTWN 366
T P P P+ T+ AT A PA GP P PT PS
Sbjct: 553 T---PGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPP------PTPQPS-------- 595
Query: 367 QHQLAHLQ--QMCSEASGTPAPGLTGKHAAGREL--AGPGFVGKAPAYPQELC-LAQSFH 421
+A LQ Q+ G PG G A + A PG PA+ Q + Q+
Sbjct: 596 ---MADLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPG----VPAFLQGMTDFLQATQ 648
Query: 422 LKPPLEKPTPSPP 434
PP P P PP
Sbjct: 649 TAPPPPPPPPPPP 661
>gi|149158692 HLA-B associated transcript-3 isoform a [Homo sapiens]
Length = 1132
Score = 40.8 bits (94), Expect = 0.003
Identities = 89/373 (23%), Positives = 128/373 (34%), Gaps = 94/373 (25%)
Query: 89 SPYPTQAATKAGLLAIVKVPAKSILKDFDGTRARLLPEAIMNPPVAPYAT-VAPSTLAHP 147
S Y T + + I ++ +GTR P A PP A+ VAPS+
Sbjct: 362 SHYTTPMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAPPPGPGQASSVAPSST--- 418
Query: 148 QAQALARQQALQHAQTLAHAPPQTLQHPQGIPPPQALSHPQSLQQPQGLGHPQPMAQTQG 207
+ ++ A P P G PP A SHP+ ++ + H
Sbjct: 419 ------------NVESSAEGAP-----PPGPAPPPATSHPRVIR----ISHQS------- 450
Query: 208 LVHPQALAHQGLQH--------------PHNPLLHG---GRKMPD-SDAPPNVTVSTSTI 249
V P + H +Q P P HG G+++P AP V ++ T
Sbjct: 451 -VEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQTLGQQVPGFPTAPTRVVIARPTP 509
Query: 250 PLSMAATLQHSQPPDLSSIVHQINQFCQTRAGISTTSVCEGQIAN--PSPISRSLLINAS 307
P A H P +S + AG+ T + ++ + + +L+
Sbjct: 510 P---QARPSHPGGPPVSGTLQ--------GAGLGTNASLAQMVSGLVGQLLMQPVLVAQG 558
Query: 308 TRVSTHSVPTPMPSCVVNPMEHTHAATAALPA-AGPVNLPTGISRVPTGYPSDLKPVTWN 366
T P P P+ T+ AT A PA GP P PT PS
Sbjct: 559 T---PGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPP------PTPQPS-------- 601
Query: 367 QHQLAHLQ--QMCSEASGTPAPGLTGKHAAGREL--AGPGFVGKAPAYPQELC-LAQSFH 421
+A LQ Q+ G PG G A + A PG PA+ Q + Q+
Sbjct: 602 ---MADLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPG----VPAFLQGMTDFLQATQ 654
Query: 422 LKPPLEKPTPSPP 434
PP P P PP
Sbjct: 655 TAPPPPPPPPPPP 667
>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
Length = 2285
Score = 40.8 bits (94), Expect = 0.003
Identities = 78/347 (22%), Positives = 113/347 (32%), Gaps = 56/347 (16%)
Query: 132 PVAPYATVAPSTLAHPQAQALARQQALQHAQTLAHAPPQTLQHPQGI------------- 178
P PY + P +P Q A+ PP Q P G
Sbjct: 418 PGQPYGSQTPQR--YPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQS 475
Query: 179 PPPQALSHPQSLQQPQGLGHPQPMAQTQGLVHPQALAHQGLQHPHNPLLHGGRKMPDSDA 238
P PQ P S Q P H QP Q Q P L Q Q P++ +
Sbjct: 476 PHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQL--QSSQPPYS----------QQPS 523
Query: 239 PPNVTVSTSTIPLSMAATLQHSQPPDLSSIVHQINQFCQTRAGISTTSVCEGQIANPSPI 298
P S + P + T QH Q S + + Q + S Q A P P
Sbjct: 524 QPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQ 583
Query: 299 SRSLLINASTRVSTHSVPTPM--------------PSCVVNP--MEHTHAATAALPAAGP 342
S+ + T S P P PS + E + + + P++ P
Sbjct: 584 SQQ---SQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLP 640
Query: 343 VNLPTGISRVPTGYPSDLKPVTWNQHQLAHLQQMCSEASGTPAPGLTGKHAAGRELAGPG 402
+L I +P G L P + ++ Q S + +P T H G P
Sbjct: 641 -DLSGSIDDLPMGTEGALSPGV-STSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPS 698
Query: 403 FVGKAPAYPQELCLAQSFHLKP---PLEKPTPSPPVNGMAAPLAYPN 446
VG P + ++S L P P + P PP +G + + +P+
Sbjct: 699 PVGS----PASVAQSRSGPLSPAAVPGNQMPPRPP-SGQSDSIMHPS 740
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.130 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,941,983
Number of Sequences: 37866
Number of extensions: 1641874
Number of successful extensions: 8493
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 55
Number of HSP's successfully gapped in prelim test: 360
Number of HSP's that attempted gapping in prelim test: 6843
Number of HSP's gapped (non-prelim): 1587
length of query: 562
length of database: 18,247,518
effective HSP length: 107
effective length of query: 455
effective length of database: 14,195,856
effective search space: 6459114480
effective search space used: 6459114480
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.