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Search of human proteins with 116812593
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|116812593 liver-specific organic anion transporter 3TM12
[Homo sapiens]
(640 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|116812593 liver-specific organic anion transporter 3TM12 [Hom... 1287 0.0
gi|9790233 solute carrier organic anion transporter family, memb... 1030 0.0
gi|225543525 solute carrier organic anion transporter family, me... 966 0.0
gi|8394291 solute carrier organic anion transporter family, memb... 563 e-160
gi|225543118 solute carrier organic anion transporter family, me... 551 e-157
gi|225543116 solute carrier organic anion transporter family, me... 482 e-136
gi|10835099 organic anion transporting polypeptide A [Homo sapiens] 481 e-135
gi|19913403 organic anion transporting polypeptide A [Homo sapiens] 481 e-135
gi|225543114 solute carrier organic anion transporter family, me... 466 e-131
gi|222831575 solute carrier organic anion transporter family, me... 342 6e-94
gi|222831573 solute carrier organic anion transporter family, me... 342 6e-94
gi|188528663 solute carrier organic anion transporter family, me... 339 4e-93
gi|223634012 solute carrier organic anion transporter family, me... 311 1e-84
gi|6005820 solute carrier organic anion transporter family, memb... 311 1e-84
gi|225637473 solute carrier organic anion transporter family, me... 307 2e-83
gi|38679890 solute carrier organic anion transporter family, mem... 303 3e-82
gi|225637475 solute carrier organic anion transporter family, me... 271 1e-72
gi|39777594 solute carrier organic anion transporter family memb... 264 2e-70
gi|225637477 solute carrier organic anion transporter family, me... 247 2e-65
gi|223634014 solute carrier organic anion transporter family, me... 245 8e-65
gi|93277099 solute carrier organic anion transporter family, mem... 187 3e-47
gi|11863156 RECK protein precursor [Homo sapiens] 38 0.025
gi|47679099 Kazal type serine protease inhibitor 5-like 2 [Homo ... 35 0.21
gi|66082554 low density lipoprotein receptor-related protein 8 i... 33 0.62
gi|41327156 solute carrier family 16 (monocarboxylic acid transp... 33 0.81
gi|12383051 transmembrane protein with EGF-like and two follista... 33 1.1
gi|54873613 agrin [Homo sapiens] 32 1.8
gi|118600977 C3 and PZP-like, alpha-2-macroglobulin domain conta... 32 1.8
gi|13375930 suppressor of variegation 3-9 homolog 2 [Homo sapiens] 31 3.1
gi|218156275 hypothetical protein LOC374393 isoform b [Homo sapi... 31 4.0
>gi|116812593 liver-specific organic anion transporter 3TM12 [Homo
sapiens]
Length = 640
Score = 1287 bits (3331), Expect = 0.0
Identities = 640/640 (100%), Positives = 640/640 (100%)
Query: 1 MKISTTQIERRFEISSSLVGLIDGSFEIGNLFVIVFVSYFGSKLHRPKLIGIGCFLMGTG 60
MKISTTQIERRFEISSSLVGLIDGSFEIGNLFVIVFVSYFGSKLHRPKLIGIGCFLMGTG
Sbjct: 1 MKISTTQIERRFEISSSLVGLIDGSFEIGNLFVIVFVSYFGSKLHRPKLIGIGCFLMGTG 60
Query: 61 SILMALPHFFMGYYRYSKETNIDPSENSTSNLPNCLINQMLSLNRTPSEIIERGCVKESG 120
SILMALPHFFMGYYRYSKETNIDPSENSTSNLPNCLINQMLSLNRTPSEIIERGCVKESG
Sbjct: 61 SILMALPHFFMGYYRYSKETNIDPSENSTSNLPNCLINQMLSLNRTPSEIIERGCVKESG 120
Query: 121 SHMWIYVFMGNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLGTVNVMGMTGLVFAFMLG 180
SHMWIYVFMGNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLGTVNVMGMTGLVFAFMLG
Sbjct: 121 SHMWIYVFMGNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLGTVNVMGMTGLVFAFMLG 180
Query: 181 SLFAKMYVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGIVSIISSIPFFFLPLNPNKPQ 240
SLFAKMYVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGIVSIISSIPFFFLPLNPNKPQ
Sbjct: 181 SLFAKMYVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGIVSIISSIPFFFLPLNPNKPQ 240
Query: 241 KERKVSLFLHVLKTNDKRNQIANLTNRRKYITKNVTGFFQSLKSILTNPLYVIFVIFTLL 300
KERKVSLFLHVLKTNDKRNQIANLTNRRKYITKNVTGFFQSLKSILTNPLYVIFVIFTLL
Sbjct: 241 KERKVSLFLHVLKTNDKRNQIANLTNRRKYITKNVTGFFQSLKSILTNPLYVIFVIFTLL 300
Query: 301 HMSSYIASLTYIIKMVEQQYGWSASKTNFLLGVLALPAVAIGMFSGGYIIKKFKLSLVGL 360
HMSSYIASLTYIIKMVEQQYGWSASKTNFLLGVLALPAVAIGMFSGGYIIKKFKLSLVGL
Sbjct: 301 HMSSYIASLTYIIKMVEQQYGWSASKTNFLLGVLALPAVAIGMFSGGYIIKKFKLSLVGL 360
Query: 361 AKLAFCSATVHLLSQVLYFFLICESKSVAGLTLTYDGNSPVRSHVDVPLSYCNSECNCDE 420
AKLAFCSATVHLLSQVLYFFLICESKSVAGLTLTYDGNSPVRSHVDVPLSYCNSECNCDE
Sbjct: 361 AKLAFCSATVHLLSQVLYFFLICESKSVAGLTLTYDGNSPVRSHVDVPLSYCNSECNCDE 420
Query: 421 SQWEPVCGNNGITYLSPCLAGCKSSSGNKEPIVFYNCSCVEVIGLQNKNYSAHLGECPRD 480
SQWEPVCGNNGITYLSPCLAGCKSSSGNKEPIVFYNCSCVEVIGLQNKNYSAHLGECPRD
Sbjct: 421 SQWEPVCGNNGITYLSPCLAGCKSSSGNKEPIVFYNCSCVEVIGLQNKNYSAHLGECPRD 480
Query: 481 DACTRKSYVYFVIQVLDAFLCAVGLTSYSVLVIRIVQPELKALAIGFHSMIMRSLGGILV 540
DACTRKSYVYFVIQVLDAFLCAVGLTSYSVLVIRIVQPELKALAIGFHSMIMRSLGGILV
Sbjct: 481 DACTRKSYVYFVIQVLDAFLCAVGLTSYSVLVIRIVQPELKALAIGFHSMIMRSLGGILV 540
Query: 541 PIYFGALIDTTCMKWSTNSCGARGACRIYNSTYLGRAFFGLKVALIFPVLVLLTVFIFVV 600
PIYFGALIDTTCMKWSTNSCGARGACRIYNSTYLGRAFFGLKVALIFPVLVLLTVFIFVV
Sbjct: 541 PIYFGALIDTTCMKWSTNSCGARGACRIYNSTYLGRAFFGLKVALIFPVLVLLTVFIFVV 600
Query: 601 RKKSHGKDTKVLENERQVMDEANLEFLNDSEHFVPSAEEQ 640
RKKSHGKDTKVLENERQVMDEANLEFLNDSEHFVPSAEEQ
Sbjct: 601 RKKSHGKDTKVLENERQVMDEANLEFLNDSEHFVPSAEEQ 640
>gi|9790233 solute carrier organic anion transporter family, member
1B3 [Homo sapiens]
Length = 702
Score = 1030 bits (2663), Expect = 0.0
Identities = 499/637 (78%), Positives = 556/637 (87%)
Query: 1 MKISTTQIERRFEISSSLVGLIDGSFEIGNLFVIVFVSYFGSKLHRPKLIGIGCFLMGTG 60
MKIS TQIERRF+ISSSL GLIDGSFEIGNL VIVFVSYFGSKLHRPKLIGIGC LMGTG
Sbjct: 48 MKISITQIERRFDISSSLAGLIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCLLMGTG 107
Query: 61 SILMALPHFFMGYYRYSKETNIDPSENSTSNLPNCLINQMLSLNRTPSEIIERGCVKESG 120
SIL +LPHFFMGYYRYSKET+I+PSENSTS+L CLINQ LS N T EI+E+ CVKESG
Sbjct: 108 SILTSLPHFFMGYYRYSKETHINPSENSTSSLSTCLINQTLSFNGTSPEIVEKDCVKESG 167
Query: 121 SHMWIYVFMGNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLGTVNVMGMTGLVFAFMLG 180
SHMWIYVFMGNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLG++N +GM G V F LG
Sbjct: 168 SHMWIYVFMGNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLGSLNAIGMIGPVIGFALG 227
Query: 181 SLFAKMYVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGIVSIISSIPFFFLPLNPNKPQ 240
SLFAKMYVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSG+ SIISSIPFFFLP NPNKPQ
Sbjct: 228 SLFAKMYVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGLFSIISSIPFFFLPKNPNKPQ 287
Query: 241 KERKVSLFLHVLKTNDKRNQIANLTNRRKYITKNVTGFFQSLKSILTNPLYVIFVIFTLL 300
KERK+SL LHVLKTND RNQ ANLTN+ K +TKNVTGFFQSLKSILTNPLYVIF++ TLL
Sbjct: 288 KERKISLSLHVLKTNDDRNQTANLTNQGKNVTKNVTGFFQSLKSILTNPLYVIFLLLTLL 347
Query: 301 HMSSYIASLTYIIKMVEQQYGWSASKTNFLLGVLALPAVAIGMFSGGYIIKKFKLSLVGL 360
+SS+I S TY+ K +EQQYG SAS NFLLG++ +P VA GMF GG+IIKKFKLSLVG+
Sbjct: 348 QVSSFIGSFTYVFKYMEQQYGQSASHANFLLGIITIPTVATGMFLGGFIIKKFKLSLVGI 407
Query: 361 AKLAFCSATVHLLSQVLYFFLICESKSVAGLTLTYDGNSPVRSHVDVPLSYCNSECNCDE 420
AK +F ++ + L Q+LYF LICESKSVAGLTLTYDGN+ V SHVDVPLSYCNSECNCDE
Sbjct: 408 AKFSFLTSMISFLFQLLYFPLICESKSVAGLTLTYDGNNSVASHVDVPLSYCNSECNCDE 467
Query: 421 SQWEPVCGNNGITYLSPCLAGCKSSSGNKEPIVFYNCSCVEVIGLQNKNYSAHLGECPRD 480
SQWEPVCGNNGITYLSPCLAGCKSSSG K+ VFYNCSCVEV GLQN+NYSAHLGECPRD
Sbjct: 468 SQWEPVCGNNGITYLSPCLAGCKSSSGIKKHTVFYNCSCVEVTGLQNRNYSAHLGECPRD 527
Query: 481 DACTRKSYVYFVIQVLDAFLCAVGLTSYSVLVIRIVQPELKALAIGFHSMIMRSLGGILV 540
+ CTRK ++Y IQV+++ A G T++ +L ++IVQPELKALA+GF SM++R+LGGIL
Sbjct: 528 NTCTRKFFIYVAIQVINSLFSATGGTTFILLTVKIVQPELKALAMGFQSMVIRTLGGILA 587
Query: 541 PIYFGALIDTTCMKWSTNSCGARGACRIYNSTYLGRAFFGLKVALIFPVLVLLTVFIFVV 600
PIYFGALID TCMKWSTNSCGA+GACRIYNS + GR + GL +AL FP LVL VFIF +
Sbjct: 588 PIYFGALIDKTCMKWSTNSCGAQGACRIYNSVFFGRVYLGLSIALRFPALVLYIVFIFAM 647
Query: 601 RKKSHGKDTKVLENERQVMDEANLEFLNDSEHFVPSA 637
+KK GKDTK +NER+VMDEANLEFLN+ EHFVPSA
Sbjct: 648 KKKFQGKDTKASDNERKVMDEANLEFLNNGEHFVPSA 684
>gi|225543525 solute carrier organic anion transporter family,
member 1B1 [Homo sapiens]
Length = 691
Score = 966 bits (2497), Expect = 0.0
Identities = 468/637 (73%), Positives = 534/637 (83%), Gaps = 1/637 (0%)
Query: 1 MKISTTQIERRFEISSSLVGLIDGSFEIGNLFVIVFVSYFGSKLHRPKLIGIGCFLMGTG 60
MK S IERRFEISSSLVG IDGSFEIGNL VIVFVSYFGSKLHRPKLIGIGCF+MG G
Sbjct: 48 MKSSIIHIERRFEISSSLVGFIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCFIMGIG 107
Query: 61 SILMALPHFFMGYYRYSKETNIDPSENSTSNLPNCLINQMLSLNRTPSEIIERGCVKESG 120
+L ALPHFFMGYYRYSKETNI+ SENSTS L CLINQ+LSLNR EI+ +GC+KESG
Sbjct: 108 GVLTALPHFFMGYYRYSKETNINSSENSTSTLSTCLINQILSLNRASPEIVGKGCLKESG 167
Query: 121 SHMWIYVFMGNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLGTVNVMGMTGLVFAFMLG 180
S+MWIYVFMGNMLRGIGETPIVPLG+SYIDDFAKEGHSSLYLG +N + M G + F LG
Sbjct: 168 SYMWIYVFMGNMLRGIGETPIVPLGLSYIDDFAKEGHSSLYLGILNAIAMIGPIIGFTLG 227
Query: 181 SLFAKMYVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGIVSIISSIPFFFLPLNPNKPQ 240
SLF+KMYVDIGYVDLSTIRITP DSRWVGAWWL FLVSG+ SIISSIPFFFLP PNKPQ
Sbjct: 228 SLFSKMYVDIGYVDLSTIRITPTDSRWVGAWWLNFLVSGLFSIISSIPFFFLPQTPNKPQ 287
Query: 241 KERKVSLFLHVLKTNDKRNQIANLTNRRKYITKNVTGFFQSLKSILTNPLYVIFVIFTLL 300
KERK SL LHVL+TND+++Q ANLTN+ K ITKNVTGFFQS KSILTNPLYV+FV+ TLL
Sbjct: 288 KERKASLSLHVLETNDEKDQTANLTNQGKNITKNVTGFFQSFKSILTNPLYVMFVLLTLL 347
Query: 301 HMSSYIASLTYIIKMVEQQYGWSASKTNFLLGVLALPAVAIGMFSGGYIIKKFKLSLVGL 360
+SSYI + TY+ K VEQQYG +SK N LLGV+ +P A GMF GGYIIKKFKL+ VG+
Sbjct: 348 QVSSYIGAFTYVFKYVEQQYGQPSSKANILLGVITIPIFASGMFLGGYIIKKFKLNTVGI 407
Query: 361 AKLAFCSATVHLLSQVLYFFLICESKSVAGLTLTYDGNSPVRSHVDVPLSYCNSECNCDE 420
AK + +A + L +LYFF++CE+KSVAGLT+TYDGN+PV SH DVPLSYCNS+CNCDE
Sbjct: 408 AKFSCFTAVMSLSFYLLYFFILCENKSVAGLTMTYDGNNPVTSHRDVPLSYCNSDCNCDE 467
Query: 421 SQWEPVCGNNGITYLSPCLAGCKSSSGNKEPIVFYNCSCVEVIGLQNKNYSAHLGECPRD 480
SQWEPVCGNNGITY+SPCLAGCKSSSGNK+PIVFYNCSC+EV GLQN+NYSAHLGECPRD
Sbjct: 468 SQWEPVCGNNGITYISPCLAGCKSSSGNKKPIVFYNCSCLEVTGLQNRNYSAHLGECPRD 527
Query: 481 DACTRKSYVYFVIQVLDAFLCAVGLTSYSVLVIRIVQPELKALAIGFHSMIMRSLGGILV 540
DACTRK Y + IQVL+ F A+G TS+ +L+++IVQPELK+LA+GFHSM++R+LGGIL
Sbjct: 528 DACTRKFYFFVAIQVLNLFFSALGGTSHVMLIVKIVQPELKSLALGFHSMVIRALGGILA 587
Query: 541 PIYFGALIDTTCMKWSTNSCGARGACRIYNSTYLGRAFFGLKVALIFPVLVLLTVFIFVV 600
PIYFGALIDTTC+KWSTN+CG RG+CR YNST R + GL L LVL + I+ +
Sbjct: 588 PIYFGALIDTTCIKWSTNNCGTRGSCRTYNSTSFSRVYLGLSSMLRVSSLVLYIILIYAM 647
Query: 601 RKKSHGKDTKVLENERQVMDEANLEFLNDSEHFVPSA 637
+KK KD EN VMDEANLE LN ++HFVPSA
Sbjct: 648 KKKYQEKDINASEN-GSVMDEANLESLNKNKHFVPSA 683
>gi|8394291 solute carrier organic anion transporter family, member
1C1 isoform 2 [Homo sapiens]
Length = 712
Score = 563 bits (1451), Expect = e-160
Identities = 271/613 (44%), Positives = 408/613 (66%), Gaps = 15/613 (2%)
Query: 1 MKISTTQIERRFEISSSLVGLIDGSFEIGNLFVIVFVSYFGSKLHRPKLIGIGCFLMGTG 60
+K + TQIERRF+I SSLVG+IDGSFEIGNL VI FVSYFG+KLHRPK+IG GC +MG G
Sbjct: 63 LKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSYFGAKLHRPKIIGAGCVIMGVG 122
Query: 61 SILMALPHFFMGYYRYSKETNIDPSENSTSNLPNCLINQMLSLNRTPSEIIERG------ 114
++L+A+P FFM Y+Y + + PS NST ++ CL+ S ++ P ++E+
Sbjct: 123 TLLIAMPQFFMEQYKYERYS---PSSNSTLSISPCLLE---SSSQLPVSVMEKSKSKISN 176
Query: 115 -CVKESGSHMWIYVFMGNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLGTVNVMGMTGL 173
C ++ S MWIYVF+GN+LRGIGETPI PLGI+Y+DDFA E +++ Y+G V + + G
Sbjct: 177 ECEVDTSSSMWIYVFLGNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGP 236
Query: 174 VFAFMLGSLFAKMYVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGIVSIISSIPFFFLP 233
+F F+LGSL AK+YVDIG+V+L I ITPKD +WVGAWWLG+L++GI+S+++++PF++LP
Sbjct: 237 IFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLP 296
Query: 234 LN-PNKPQKERKVSLFLHVLKTNDKRNQIANLTNRRKYITKNVTGFFQSLKSILTNPLYV 292
+ P +E S D I + F SLK++ NP+Y
Sbjct: 297 KSLPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYF 356
Query: 293 IFVIFTLLHMSSYIASLTYIIKMVEQQYGWSASKTNFLLGVLALPAVAIGMFSGGYIIKK 352
+++ + + +S +TY K +EQQYG S+S+ NF++G++ +PAVA+G+FSGG ++KK
Sbjct: 357 LYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKK 416
Query: 353 FKLSLVGLAKLAFCSATVHLLSQVLYFFLICESKSVAGLTLTYDGNSPVRSHVDVPLSYC 412
F++S+ G AKL S+ L + F L CE+ VAGLT++Y G PV H S C
Sbjct: 417 FRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDC 476
Query: 413 NSECNCDESQWEPVCGNNGITYLSPCLAGCKSSSGNKEPIVFYNCSCVEVIGLQNKNYSA 472
NS C C E++WEP+CG NGITY+S CLAGC++S+ + + I+FYNC+CV + ++ N S
Sbjct: 477 NSRCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSG 536
Query: 473 HLGECPRDDACTRKSYVYFVIQVLDAFLCAVGLTSYSVLVIRIVQPELKALAIGFHSMIM 532
+G C +D+ C + + VI V+ ++ ++G +L++R ++P+LK+ A+G +++ +
Sbjct: 537 IVGRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAI 596
Query: 533 RSLGGILVPIYFGALIDTTCMKWSTNSCGARGACRIYNSTYLGRAFFGLKVALIFPVLVL 592
R L GI P+YFG LIDT+C+KW CG+RG+CR+Y+S + GL V ++ V +L
Sbjct: 597 RVLAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRHIYLGLTV-ILGTVSIL 655
Query: 593 LTVFIFVVRKKSH 605
L++ + + KK++
Sbjct: 656 LSIAVLFILKKNY 668
>gi|225543118 solute carrier organic anion transporter family,
member 1C1 isoform 1 [Homo sapiens]
Length = 730
Score = 551 bits (1420), Expect = e-157
Identities = 263/579 (45%), Positives = 390/579 (67%), Gaps = 14/579 (2%)
Query: 1 MKISTTQIERRFEISSSLVGLIDGSFEIGNLFVIVFVSYFGSKLHRPKLIGIGCFLMGTG 60
+K + TQIERRF+I SSLVG+IDGSFEIGNL VI FVSYFG+KLHRPK+IG GC +MG G
Sbjct: 63 LKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSYFGAKLHRPKIIGAGCVIMGVG 122
Query: 61 SILMALPHFFMGYYRYSKETNIDPSENSTSNLPNCLINQMLSLNRTPSEIIERG------ 114
++L+A+P FFM Y+Y + + PS NST ++ CL+ S ++ P ++E+
Sbjct: 123 TLLIAMPQFFMEQYKYERYS---PSSNSTLSISPCLLE---SSSQLPVSVMEKSKSKISN 176
Query: 115 -CVKESGSHMWIYVFMGNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLGTVNVMGMTGL 173
C ++ S MWIYVF+GN+LRGIGETPI PLGI+Y+DDFA E +++ Y+G V + + G
Sbjct: 177 ECEVDTSSSMWIYVFLGNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGP 236
Query: 174 VFAFMLGSLFAKMYVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGIVSIISSIPFFFLP 233
+F F+LGSL AK+YVDIG+V+L I ITPKD +WVGAWWLG+L++GI+S+++++PF++LP
Sbjct: 237 IFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLP 296
Query: 234 LN-PNKPQKERKVSLFLHVLKTNDKRNQIANLTNRRKYITKNVTGFFQSLKSILTNPLYV 292
+ P +E S D I + F SLK++ NP+Y
Sbjct: 297 KSLPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYF 356
Query: 293 IFVIFTLLHMSSYIASLTYIIKMVEQQYGWSASKTNFLLGVLALPAVAIGMFSGGYIIKK 352
+++ + + +S +TY K +EQQYG S+S+ NF++G++ +PAVA+G+FSGG ++KK
Sbjct: 357 LYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKK 416
Query: 353 FKLSLVGLAKLAFCSATVHLLSQVLYFFLICESKSVAGLTLTYDGNSPVRSHVDVPLSYC 412
F++S+ G AKL S+ L + F L CE+ VAGLT++Y G PV H S C
Sbjct: 417 FRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDC 476
Query: 413 NSECNCDESQWEPVCGNNGITYLSPCLAGCKSSSGNKEPIVFYNCSCVEVIGLQNKNYSA 472
NS C C E++WEP+CG NGITY+S CLAGC++S+ + + I+FYNC+CV + ++ N S
Sbjct: 477 NSRCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSG 536
Query: 473 HLGECPRDDACTRKSYVYFVIQVLDAFLCAVGLTSYSVLVIRIVQPELKALAIGFHSMIM 532
+G C +D+ C + + VI V+ ++ ++G +L++R ++P+LK+ A+G +++ +
Sbjct: 537 IVGRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAI 596
Query: 533 RSLGGILVPIYFGALIDTTCMKWSTNSCGARGACRIYNS 571
R L GI P+YFG LIDT+C+KW CG+RG+CR+Y+S
Sbjct: 597 RVLAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDS 635
>gi|225543116 solute carrier organic anion transporter family,
member 1C1 isoform 3 [Homo sapiens]
Length = 663
Score = 482 bits (1240), Expect = e-136
Identities = 243/606 (40%), Positives = 370/606 (61%), Gaps = 50/606 (8%)
Query: 1 MKISTTQIERRFEISSSLVGLIDGSFEIGNLFVIVFVSYFGSKLHRPKLIGIGCFLMGTG 60
+K + TQIERRF+I SSLVG+IDGSFEIGNL VI FVSYFG+KLHRPK+IG GC +MG G
Sbjct: 63 LKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSYFGAKLHRPKIIGAGCVIMGVG 122
Query: 61 SILMALPHFFMGYYRYSKETNIDPSENSTSNLPNCLINQMLSLNRTPSEIIERGCVKESG 120
++L+A+P FFM Y+Y + + PS NST ++ CL+ S ++ P ++E+ K S
Sbjct: 123 TLLIAMPQFFMEQYKYERYS---PSSNSTLSISPCLLE---SSSQLPVSVMEKSKSKISN 176
Query: 121 SHMWIYVFMGNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLGTVNVMGMTGLVFAFMLG 180
G V + + G +F F+LG
Sbjct: 177 ------------------------------------------GCVQTVAIIGPIFGFLLG 194
Query: 181 SLFAKMYVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGIVSIISSIPFFFLPLN-PNKP 239
SL AK+YVDIG+V+L I ITPKD +WVGAWWLG+L++GI+S+++++PF++LP + P
Sbjct: 195 SLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKSLPRSQ 254
Query: 240 QKERKVSLFLHVLKTNDKRNQIANLTNRRKYITKNVTGFFQSLKSILTNPLYVIFVIFTL 299
+E S D I + F SLK++ NP+Y +++ +
Sbjct: 255 SREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLYLCTST 314
Query: 300 LHMSSYIASLTYIIKMVEQQYGWSASKTNFLLGVLALPAVAIGMFSGGYIIKKFKLSLVG 359
+ +S +TY K +EQQYG S+S+ NF++G++ +PAVA+G+FSGG ++KKF++S+ G
Sbjct: 315 VQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFRISVCG 374
Query: 360 LAKLAFCSATVHLLSQVLYFFLICESKSVAGLTLTYDGNSPVRSHVDVPLSYCNSECNCD 419
AKL S+ L + F L CE+ VAGLT++Y G PV H S CNS C C
Sbjct: 375 AAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNSRCKCS 434
Query: 420 ESQWEPVCGNNGITYLSPCLAGCKSSSGNKEPIVFYNCSCVEVIGLQNKNYSAHLGECPR 479
E++WEP+CG NGITY+S CLAGC++S+ + + I+FYNC+CV + ++ N S +G C +
Sbjct: 435 ETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIVGRCQK 494
Query: 480 DDACTRKSYVYFVIQVLDAFLCAVGLTSYSVLVIRIVQPELKALAIGFHSMIMRSLGGIL 539
D+ C + + VI V+ ++ ++G +L++R ++P+LK+ A+G +++ +R L GI
Sbjct: 495 DNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLAGIP 554
Query: 540 VPIYFGALIDTTCMKWSTNSCGARGACRIYNSTYLGRAFFGLKVALIFPVLVLLTVFIFV 599
P+YFG LIDT+C+KW CG+RG+CR+Y+S + GL V ++ V +LL++ +
Sbjct: 555 APVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRHIYLGLTV-ILGTVSILLSIAVLF 613
Query: 600 VRKKSH 605
+ KK++
Sbjct: 614 ILKKNY 619
>gi|10835099 organic anion transporting polypeptide A [Homo sapiens]
Length = 670
Score = 481 bits (1237), Expect = e-135
Identities = 250/605 (41%), Positives = 371/605 (61%), Gaps = 22/605 (3%)
Query: 1 MKISTTQIERRFEISSSLVGLIDGSFEIGNLFVIVFVSYFGSKLHRPKLIGIGCFLMGTG 60
M TQIER+F I +SLVG I+GSFEIGNL +I+FVSYFG+KLHRP +IGIGC +MG G
Sbjct: 40 MNSMLTQIERQFNIPTSLVGFINGSFEIGNLLLIIFVSYFGTKLHRPIMIGIGCVVMGLG 99
Query: 61 SILMALPHFFMGYYRYSKETNIDPSENSTSNLPNCLIN--QMLSLNRTPSEIIERGCVKE 118
L +LPHF M Y Y E+ + S N +SN C+ N Q+L + PSE C KE
Sbjct: 100 CFLKSLPHFLMNQYEY--ESTVSVSGNLSSNSFLCMENGTQILRPTQDPSE-----CTKE 152
Query: 119 SGSHMWIYVFMGNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLGTVNVMGMTGLVFAFM 178
S MW+YV +GN++RG+GETPI+PLGISYI+DFAK +S LY+G V + G + +
Sbjct: 153 VKSLMWVYVLVGNIVRGMGETPILPLGISYIEDFAKFENSPLYIGLVETGAIIGPLIGLL 212
Query: 179 LGSLFAKMYVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGIVSIISSIPFFFLPLNPNK 238
L S A +YVD G+V+ + ITP D+RWVGAWW GFL+ V+++++IPFFFLP K
Sbjct: 213 LASFCANVYVDTGFVNTDDLIITPTDTRWVGAWWFGFLICAGVNVLTAIPFFFLPNTLPK 272
Query: 239 PQKERKVSLFLHVLKTNDKRNQIANLTNRRKYITKNVTGFFQSLKSILTNPLYVIFVIFT 298
E ++K ++ Q + + ITK+ F +KS+ NP+Y++F++ +
Sbjct: 273 EGLETNAD----IIKNENEDKQKEEVKKEKYGITKD---FLPFMKSLSCNPIYMLFILVS 325
Query: 299 LLHMSSYIASLTYIIKMVEQQYGWSASKTNFLLGVLALPAVAIGMFSGGYIIKKFKLSLV 358
++ ++++ ++++ K +EQQYG S+S FL+G+ LP + IG GG I+KKFK+++
Sbjct: 326 VIQFNAFVNMISFMPKYLEQQYGISSSDAIFLMGIYNLPPICIGYIIGGLIMKKFKITVK 385
Query: 359 GLAKLAFCSATVHLLSQVLYFFLICESKSVAGLTLTYDGNSPVRSHVDVPL-SYCNSECN 417
A + + + L L F + CE+ SV G+ +Y+G P +V+ + + CN +CN
Sbjct: 386 QAAHIGCWLSLLEYLLYFLSFLMTCENSSVVGINTSYEG-IPQDLYVENDIFADCNVDCN 444
Query: 418 CDESQWEPVCGNNGITYLSPCLAGCKSSSGNKEPIVFYNCSCVEVIGLQNKNYSAHLGEC 477
C W+PVCGNNG++YLS CLAGC++S G +VF NCSC++ G N SA LG C
Sbjct: 445 CPSKIWDPVCGNNGLSYLSACLAGCETSIGTGINMVFQNCSCIQTSG----NSSAVLGLC 500
Query: 478 PRDDACTRKSYVYFVIQVLDAFLCAVGLTSYSVLVIRIVQPELKALAIGFHSMIMRSLGG 537
+ C+ + ++ + +F+ ++ ++++R ++ E K+L +G H+ R G
Sbjct: 501 DKGPDCSLMLQYFLILSAMSSFIYSLAAIPGYMVLLRCMKSEEKSLGVGLHTFCTRVFAG 560
Query: 538 ILVPIYFGALIDTTCMKWSTNSCGARGACRIYNSTYLGRAFFGLKVALIFPVLVLLTVFI 597
I PIYFGAL+D+TC+ W T CG GACRIY+ST + GL AL V + +
Sbjct: 561 IPAPIYFGALMDSTCLHWGTLKCGESGACRIYDSTTFRYIYLGLPAALRGSSFVPALIIL 620
Query: 598 FVVRK 602
++RK
Sbjct: 621 ILLRK 625
>gi|19913403 organic anion transporting polypeptide A [Homo sapiens]
Length = 670
Score = 481 bits (1237), Expect = e-135
Identities = 250/605 (41%), Positives = 371/605 (61%), Gaps = 22/605 (3%)
Query: 1 MKISTTQIERRFEISSSLVGLIDGSFEIGNLFVIVFVSYFGSKLHRPKLIGIGCFLMGTG 60
M TQIER+F I +SLVG I+GSFEIGNL +I+FVSYFG+KLHRP +IGIGC +MG G
Sbjct: 40 MNSMLTQIERQFNIPTSLVGFINGSFEIGNLLLIIFVSYFGTKLHRPIMIGIGCVVMGLG 99
Query: 61 SILMALPHFFMGYYRYSKETNIDPSENSTSNLPNCLIN--QMLSLNRTPSEIIERGCVKE 118
L +LPHF M Y Y E+ + S N +SN C+ N Q+L + PSE C KE
Sbjct: 100 CFLKSLPHFLMNQYEY--ESTVSVSGNLSSNSFLCMENGTQILRPTQDPSE-----CTKE 152
Query: 119 SGSHMWIYVFMGNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLGTVNVMGMTGLVFAFM 178
S MW+YV +GN++RG+GETPI+PLGISYI+DFAK +S LY+G V + G + +
Sbjct: 153 VKSLMWVYVLVGNIVRGMGETPILPLGISYIEDFAKFENSPLYIGLVETGAIIGPLIGLL 212
Query: 179 LGSLFAKMYVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGIVSIISSIPFFFLPLNPNK 238
L S A +YVD G+V+ + ITP D+RWVGAWW GFL+ V+++++IPFFFLP K
Sbjct: 213 LASFCANVYVDTGFVNTDDLIITPTDTRWVGAWWFGFLICAGVNVLTAIPFFFLPNTLPK 272
Query: 239 PQKERKVSLFLHVLKTNDKRNQIANLTNRRKYITKNVTGFFQSLKSILTNPLYVIFVIFT 298
E ++K ++ Q + + ITK+ F +KS+ NP+Y++F++ +
Sbjct: 273 EGLETNAD----IIKNENEDKQKEEVKKEKYGITKD---FLPFMKSLSCNPIYMLFILVS 325
Query: 299 LLHMSSYIASLTYIIKMVEQQYGWSASKTNFLLGVLALPAVAIGMFSGGYIIKKFKLSLV 358
++ ++++ ++++ K +EQQYG S+S FL+G+ LP + IG GG I+KKFK+++
Sbjct: 326 VIQFNAFVNMISFMPKYLEQQYGISSSDAIFLMGIYNLPPICIGYIIGGLIMKKFKITVK 385
Query: 359 GLAKLAFCSATVHLLSQVLYFFLICESKSVAGLTLTYDGNSPVRSHVDVPL-SYCNSECN 417
A + + + L L F + CE+ SV G+ +Y+G P +V+ + + CN +CN
Sbjct: 386 QAAHIGCWLSLLEYLLYFLSFLMTCENSSVVGINTSYEG-IPQDLYVENDIFADCNVDCN 444
Query: 418 CDESQWEPVCGNNGITYLSPCLAGCKSSSGNKEPIVFYNCSCVEVIGLQNKNYSAHLGEC 477
C W+PVCGNNG++YLS CLAGC++S G +VF NCSC++ G N SA LG C
Sbjct: 445 CPSKIWDPVCGNNGLSYLSACLAGCETSIGTGINMVFQNCSCIQTSG----NSSAVLGLC 500
Query: 478 PRDDACTRKSYVYFVIQVLDAFLCAVGLTSYSVLVIRIVQPELKALAIGFHSMIMRSLGG 537
+ C+ + ++ + +F+ ++ ++++R ++ E K+L +G H+ R G
Sbjct: 501 DKGPDCSLMLQYFLILSAMSSFIYSLAAIPGYMVLLRCMKSEEKSLGVGLHTFCTRVFAG 560
Query: 538 ILVPIYFGALIDTTCMKWSTNSCGARGACRIYNSTYLGRAFFGLKVALIFPVLVLLTVFI 597
I PIYFGAL+D+TC+ W T CG GACRIY+ST + GL AL V + +
Sbjct: 561 IPAPIYFGALMDSTCLHWGTLKCGESGACRIYDSTTFRYIYLGLPAALRGSSFVPALIIL 620
Query: 598 FVVRK 602
++RK
Sbjct: 621 ILLRK 625
>gi|225543114 solute carrier organic anion transporter family,
member 1C1 isoform 4 [Homo sapiens]
Length = 612
Score = 466 bits (1198), Expect = e-131
Identities = 221/523 (42%), Positives = 341/523 (65%), Gaps = 14/523 (2%)
Query: 57 MGTGSILMALPHFFMGYYRYSKETNIDPSENSTSNLPNCLINQMLSLNRTPSEIIERG-- 114
MG G++L+A+P FFM Y+Y + + PS NST ++ CL+ S ++ P ++E+
Sbjct: 1 MGVGTLLIAMPQFFMEQYKYERYS---PSSNSTLSISPCLLE---SSSQLPVSVMEKSKS 54
Query: 115 -----CVKESGSHMWIYVFMGNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLGTVNVMG 169
C ++ S MWIYVF+GN+LRGIGETPI PLGI+Y+DDFA E +++ Y+G V +
Sbjct: 55 KISNECEVDTSSSMWIYVFLGNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVA 114
Query: 170 MTGLVFAFMLGSLFAKMYVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGIVSIISSIPF 229
+ G +F F+LGSL AK+YVDIG+V+L I ITPKD +WVGAWWLG+L++GI+S+++++PF
Sbjct: 115 IIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPF 174
Query: 230 FFLPLN-PNKPQKERKVSLFLHVLKTNDKRNQIANLTNRRKYITKNVTGFFQSLKSILTN 288
++LP + P +E S D I + F SLK++ N
Sbjct: 175 WYLPKSLPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGN 234
Query: 289 PLYVIFVIFTLLHMSSYIASLTYIIKMVEQQYGWSASKTNFLLGVLALPAVAIGMFSGGY 348
P+Y +++ + + +S +TY K +EQQYG S+S+ NF++G++ +PAVA+G+FSGG
Sbjct: 235 PVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGI 294
Query: 349 IIKKFKLSLVGLAKLAFCSATVHLLSQVLYFFLICESKSVAGLTLTYDGNSPVRSHVDVP 408
++KKF++S+ G AKL S+ L + F L CE+ VAGLT++Y G PV H
Sbjct: 295 VMKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERAL 354
Query: 409 LSYCNSECNCDESQWEPVCGNNGITYLSPCLAGCKSSSGNKEPIVFYNCSCVEVIGLQNK 468
S CNS C C E++WEP+CG NGITY+S CLAGC++S+ + + I+FYNC+CV + ++
Sbjct: 355 FSDCNSRCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSG 414
Query: 469 NYSAHLGECPRDDACTRKSYVYFVIQVLDAFLCAVGLTSYSVLVIRIVQPELKALAIGFH 528
N S +G C +D+ C + + VI V+ ++ ++G +L++R ++P+LK+ A+G +
Sbjct: 415 NSSGIVGRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIY 474
Query: 529 SMIMRSLGGILVPIYFGALIDTTCMKWSTNSCGARGACRIYNS 571
++ +R L GI P+YFG LIDT+C+KW CG+RG+CR+Y+S
Sbjct: 475 TLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDS 517
>gi|222831575 solute carrier organic anion transporter family,
member 3A1 isoform 1 [Homo sapiens]
Length = 710
Score = 342 bits (877), Expect = 6e-94
Identities = 208/607 (34%), Positives = 321/607 (52%), Gaps = 31/607 (5%)
Query: 6 TQIERRFEISSSLVGLIDGSFEIGNLFVIVFVSYFGSKLHRPKLIGIGCFLMGTGSILMA 65
T +ERRF + S+ VG+I SFEIGNL +I+FVSYFG++ HRP+LIG G +M G++L A
Sbjct: 65 TTLERRFNLQSADVGVIASSFEIGNLALILFVSYFGARGHRPRLIGCGGIVMALGALLSA 124
Query: 66 LPHFFMGYYRYSKETNIDPSENSTSNLPNCLINQMLSLNRTPSEIIERGCVKESGSHMWI 125
LP F Y+Y +E C N ++I R + + + M++
Sbjct: 125 LPEFLTHQYKYEAGEIRWGAEGRDV----CAANGSGGDEGPDPDLICRN--RTATNMMYL 178
Query: 126 YVFMGNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLGTVNVMGMTGLVFAFMLGSLFAK 185
+ +L GIG TP+ PLG+SYIDD + SSLY+G + M + G F+LGS K
Sbjct: 179 LLIGAQVLLGIGATPVQPLGVSYIDDHVRRKDSSLYIGILFTMLVFGPACGFILGSFCTK 238
Query: 186 MYVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGIVSIISSIPFFFLP--LNP-NKPQKE 242
+YVD ++D S + ITP D RW+GAWW GFL+ G + SS+ F P L P ++P E
Sbjct: 239 IYVDAVFIDTSNLDITPDDPRWIGAWWGGFLLCGALLFFSSLLMFGFPQSLPPHSEPAME 298
Query: 243 RKVSLFLHVLKTNDKRNQIANLTNRRKYITKNVTGFFQSL-------KSILTNPLYVIFV 295
+ ++ + + +R + +N R + FQ L K +L+NP++ +
Sbjct: 299 SEQAM---LSEREYERPKPSNGVLRHPLEPDSSASCFQQLRVIPKVTKHLLSNPVFTCII 355
Query: 296 IFTLLHMSSYIASLTYIIKMVEQQYGWSASKTNFLLGVLALPAVAIGMFSGGYIIKKFKL 355
+ + ++ ++ K +EQQ+ + S N LLG+ A+P +G+F GG ++KK L
Sbjct: 356 LAACMEIAVVAGFAAFLGKYLEQQFNLTTSSANQLLGMTAIPCACLGIFLGGLLVKKLSL 415
Query: 356 SLVGLAKLAFCSATVHLLSQVLYFFLICESKSVAGLTLTYDGNSPVRSHVDVPLSYCNSE 415
S +G ++A V V + FL C++ VAG+T+ Y GNS P S CN+
Sbjct: 416 SALGAIRMAMLVNLVSTACYVSFLFLGCDTGPVAGVTVPY-GNSTAPGSALDPYSPCNNN 474
Query: 416 CNCDESQWEPVCGNNGITYLSPCLAGCKSSSGNKEPIVFYNCSCVEVIGLQNKNYSAHLG 475
C C + PVCG +GITYLS C AGC S++ C+C+ + +N G
Sbjct: 475 CECQTDSFTPVCGADGITYLSACFAGCNSTN-------LTGCACLTTVPAENATVVP--G 525
Query: 476 ECPRDDACTRKSYVYFVIQVLDAFLCAVGLTSYSVLVIRIVQPELKALAIGFHSMIMRSL 535
+CP C + + + + + A+ T +++IR V PELK+ A+G +++R L
Sbjct: 526 KCP-SPGCQEAFLTFLCVMCICSLIGAMAQTPSVIILIRTVSPELKSYALGVLFLLLRLL 584
Query: 536 GGILVPIYFGALIDTTCMKWSTNSCGARGACRIYNSTYLGRAFFGLKVALIFPVLVLLTV 595
G I P+ FGA ID+TC+ WST CG +GAC +Y++ + + +AL +L T
Sbjct: 585 GFIPPPLIFGAGIDSTCLFWST-FCGEQGACVLYDNVVYRYLYVSIAIALKSFAFILYTT 643
Query: 596 FIFVVRK 602
+RK
Sbjct: 644 TWQCLRK 650
>gi|222831573 solute carrier organic anion transporter family,
member 3A1 isoform 2 [Homo sapiens]
Length = 692
Score = 342 bits (877), Expect = 6e-94
Identities = 208/607 (34%), Positives = 321/607 (52%), Gaps = 31/607 (5%)
Query: 6 TQIERRFEISSSLVGLIDGSFEIGNLFVIVFVSYFGSKLHRPKLIGIGCFLMGTGSILMA 65
T +ERRF + S+ VG+I SFEIGNL +I+FVSYFG++ HRP+LIG G +M G++L A
Sbjct: 65 TTLERRFNLQSADVGVIASSFEIGNLALILFVSYFGARGHRPRLIGCGGIVMALGALLSA 124
Query: 66 LPHFFMGYYRYSKETNIDPSENSTSNLPNCLINQMLSLNRTPSEIIERGCVKESGSHMWI 125
LP F Y+Y +E C N ++I R + + + M++
Sbjct: 125 LPEFLTHQYKYEAGEIRWGAEGRDV----CAANGSGGDEGPDPDLICRN--RTATNMMYL 178
Query: 126 YVFMGNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLGTVNVMGMTGLVFAFMLGSLFAK 185
+ +L GIG TP+ PLG+SYIDD + SSLY+G + M + G F+LGS K
Sbjct: 179 LLIGAQVLLGIGATPVQPLGVSYIDDHVRRKDSSLYIGILFTMLVFGPACGFILGSFCTK 238
Query: 186 MYVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGIVSIISSIPFFFLP--LNP-NKPQKE 242
+YVD ++D S + ITP D RW+GAWW GFL+ G + SS+ F P L P ++P E
Sbjct: 239 IYVDAVFIDTSNLDITPDDPRWIGAWWGGFLLCGALLFFSSLLMFGFPQSLPPHSEPAME 298
Query: 243 RKVSLFLHVLKTNDKRNQIANLTNRRKYITKNVTGFFQSL-------KSILTNPLYVIFV 295
+ ++ + + +R + +N R + FQ L K +L+NP++ +
Sbjct: 299 SEQAM---LSEREYERPKPSNGVLRHPLEPDSSASCFQQLRVIPKVTKHLLSNPVFTCII 355
Query: 296 IFTLLHMSSYIASLTYIIKMVEQQYGWSASKTNFLLGVLALPAVAIGMFSGGYIIKKFKL 355
+ + ++ ++ K +EQQ+ + S N LLG+ A+P +G+F GG ++KK L
Sbjct: 356 LAACMEIAVVAGFAAFLGKYLEQQFNLTTSSANQLLGMTAIPCACLGIFLGGLLVKKLSL 415
Query: 356 SLVGLAKLAFCSATVHLLSQVLYFFLICESKSVAGLTLTYDGNSPVRSHVDVPLSYCNSE 415
S +G ++A V V + FL C++ VAG+T+ Y GNS P S CN+
Sbjct: 416 SALGAIRMAMLVNLVSTACYVSFLFLGCDTGPVAGVTVPY-GNSTAPGSALDPYSPCNNN 474
Query: 416 CNCDESQWEPVCGNNGITYLSPCLAGCKSSSGNKEPIVFYNCSCVEVIGLQNKNYSAHLG 475
C C + PVCG +GITYLS C AGC S++ C+C+ + +N G
Sbjct: 475 CECQTDSFTPVCGADGITYLSACFAGCNSTN-------LTGCACLTTVPAENATVVP--G 525
Query: 476 ECPRDDACTRKSYVYFVIQVLDAFLCAVGLTSYSVLVIRIVQPELKALAIGFHSMIMRSL 535
+CP C + + + + + A+ T +++IR V PELK+ A+G +++R L
Sbjct: 526 KCP-SPGCQEAFLTFLCVMCICSLIGAMAQTPSVIILIRTVSPELKSYALGVLFLLLRLL 584
Query: 536 GGILVPIYFGALIDTTCMKWSTNSCGARGACRIYNSTYLGRAFFGLKVALIFPVLVLLTV 595
G I P+ FGA ID+TC+ WST CG +GAC +Y++ + + +AL +L T
Sbjct: 585 GFIPPPLIFGAGIDSTCLFWST-FCGEQGACVLYDNVVYRYLYVSIAIALKSFAFILYTT 643
Query: 596 FIFVVRK 602
+RK
Sbjct: 644 TWQCLRK 650
>gi|188528663 solute carrier organic anion transporter family,
member 2A1 [Homo sapiens]
Length = 643
Score = 339 bits (870), Expect = 4e-93
Identities = 206/605 (34%), Positives = 321/605 (53%), Gaps = 31/605 (5%)
Query: 2 KISTTQIERRFEISSSLVGLIDGSFEIGNLFVIVFVSYFGSKLHRPKLIGIGCFLMGTGS 61
K S T IE+RF +SSS GLI EI N +I+FVSYFGS++HRP+LIGIG + G+
Sbjct: 53 KSSLTTIEKRFGLSSSSSGLISSLNEISNAILIIFVSYFGSRVHRPRLIGIGGLFLAAGA 112
Query: 62 ILMALPHFFMGYYRYSKETNIDPSENSTSNLPNCLINQMLSLNRTPSEIIERGCVKESGS 121
++ LPHF Y+Y T NS C L + + KE+ S
Sbjct: 113 FILTLPHFLSEPYQY---TLASTGNNSRLQAELCQ-KHWQDLPPSKCHSTTQNPQKETSS 168
Query: 122 HMWIYVFMGNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLGTVNVMGMTGLVFAFMLGS 181
MW + + +L GIG PI P GISY+DDF++ +S LY+ + + + G F ++LGS
Sbjct: 169 -MWGLMVVAQLLAGIGTVPIQPFGISYVDDFSEPSNSPLYISILFAISVFGPAFGYLLGS 227
Query: 182 LFAKMYVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGIVSIISSIPFFFLPLNPNKPQK 241
+ +++VD G V+ + + + P D RW+GAWWLG L+S + +++S PFFF P K
Sbjct: 228 VMLQIFVDYGRVNTAAVNLVPGDPRWIGAWWLGLLISSALLVLTSFPFFFFPRAMPIGAK 287
Query: 242 ERKVSLFLHVLKTNDKRNQIANLTNRRKYITKNVTGFFQSLKSILTNPLYVIFVIFTLLH 301
T D+ ++ +R + + F +L N L+V+ V+
Sbjct: 288 RAPA--------TADEARKLEEAKSRGS-LVDFIKRFPCIFLRLLMNSLFVL-VVLAQCT 337
Query: 302 MSSYIASL-TYIIKMVEQQYGWSASKTNFLLGVLALPAVAIGMFSGGYIIKKFKLSLVGL 360
SS IA L T++ K +E+QYG SA+ NFL+G + LPA A+GM GG ++K+F SL +
Sbjct: 338 FSSVIAGLSTFLNKFLEKQYGTSAAYANFLIGAVNLPAAALGMLFGGILMKRFVFSLQAI 397
Query: 361 AKLAFCSATVHLLSQVLYFFLICESKSVAGLTLTYDGNSPVRSHVDVPLSYCNSECNCDE 420
++A T+ ++ V FF+ C + +VA + Y ++ H P C +C+C +
Sbjct: 398 PRIATTIITISMILCVPLFFMGCSTPTVAEV---YPPSTSSSIHPQSPA--CRRDCSCPD 452
Query: 421 SQWEPVCGNNGITYLSPCLAGCKS---SSGNKEPIVFYNCSCVEVIGLQNKNYSAHLGEC 477
S + PVCG+NGI YLSPC AGC + SS + +++ NCSCV + SA G C
Sbjct: 453 SIFHPVCGDNGIEYLSPCHAGCSNINMSSATSKQLIYLNCSCV-----TGGSASAKTGSC 507
Query: 478 PRDDACTRKSYVYFVIQVLDAFLCAVGLTSYSVLVIRIVQPELKALAIGFHSMIMRSLGG 537
P A ++ + V + + + ++V+R+V E K+ AIG ++MR L
Sbjct: 508 PVPCAHFLLPAIFLISFV--SLIACISHNPLYMMVLRVVNQEEKSFAIGVQFLLMRLLAW 565
Query: 538 ILVPIYFGALIDTTCMKWSTNSCGARGACRIYNSTYLGRAFFGLKVALIFPVLVLLTVFI 597
+ P +G ID +C++W++ G RGAC Y++ L + GL++ ++LL
Sbjct: 566 LPSPALYGLTIDHSCIRWNSLCLGRRGACAYYDNDALRDRYLGLQMGYKALGMLLLCFIS 625
Query: 598 FVVRK 602
+ V+K
Sbjct: 626 WRVKK 630
>gi|223634012 solute carrier organic anion transporter family,
member 2B1 isoform 2 [Homo sapiens]
Length = 687
Score = 311 bits (797), Expect = 1e-84
Identities = 206/642 (32%), Positives = 316/642 (49%), Gaps = 59/642 (9%)
Query: 1 MKISTTQIERRFEISSSLVGLIDGSFEIGNLFVIVFVSYFGSKLHRPKLIGIGCFLMGTG 60
+K S + +E+RF +SS GL+ E+GN +IVFVSYFGS++HRP++IG G L+
Sbjct: 47 LKSSISTVEKRFGLSSQTSGLLASFNEVGNTALIVFVSYFGSRVHRPRMIGYGAILVALA 106
Query: 61 SILMALPHFFMGYYRYSKETNIDPSENSTSNL--PNCLINQMLSLNRTPSEIIERGCVKE 118
+LM LPHF YRY + D ++ ++L P N S E +
Sbjct: 107 GLLMTLPHFISEPYRYDNTSPEDMPQDFKASLCLPTTSAPASAPSNGNCSSYTETQHLSV 166
Query: 119 SGSHMWIYVFMGNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLGTVNVMGMTGLVFAFM 178
G +F+ L G+G PI P GISYIDDFA +S LYLG + + M G AF
Sbjct: 167 VG-----IMFVAQTLLGVGGVPIQPFGISYIDDFAHNSNSPLYLGILFAVTMMGPGLAFG 221
Query: 179 LGSLFAKMYVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGIVSIISSIPFFFLPLNPNK 238
LGSL ++YVDI + I +T KD RWVGAWWLGFL++ +++IP+FF P
Sbjct: 222 LGSLMLRLYVDINQMPEGGISLTIKDPRWVGAWWLGFLIAAGAVALAAIPYFFFP--KEM 279
Query: 239 PQKERKVSLFLHVL-----------------------KTNDKRNQIA-NLTNRRKYITKN 274
P+++R++ VL K D QIA NLT + +
Sbjct: 280 PKEKRELQFRRKVLAVTDSPARKGKDSPSKQSPGESTKKQDGLVQIAPNLT-----VIQF 334
Query: 275 VTGFFQSLKSILTNPLYVIFVIFTLLHMSSYIASLTYIIKMVEQQYGWSASKTNFLLGVL 334
+ F + L L +P++++ V+ + S T++ K +E+Q+ +AS N L+G L
Sbjct: 335 IKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAGMATFLPKFLERQFSITASYANLLIGCL 394
Query: 335 ALPAVAIGMFSGGYIIKKFKLSLVGLAKLAFCSATVHLLSQVLYFFLICESKSVAGLTLT 394
+ P+V +G+ GG ++K+ L VG L + L + FF+ C S +AG+T
Sbjct: 395 SFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLGMLLCLFFSLPLFFIGCSSHQIAGIT-- 452
Query: 395 YDGNSPVRSHVDVPLS-YCNSECNCDESQWEPVCG-NNGITYLSPCLAGCKS----SSGN 448
+H + LS C C+C + PVC + + Y++PC AGC S + +
Sbjct: 453 ----HQTSAHPGLELSPSCMEACSCPLDGFNPVCDPSTRVEYITPCHAGCSSWVVQDALD 508
Query: 449 KEPIVFYNCSCVEVIGLQNKNYSAHLGECPRDDACTRKSYVYFVIQVLDAFLCAVGLTSY 508
+ + NCSCV + G C D C+ + ++ L + L + T
Sbjct: 509 NSQVFYTNCSCVV------EGNPVLAGSC--DSTCSHLVVPFLLLVSLGSALACLTHTPS 560
Query: 509 SVLVIRIVQPELKALAIGFHSMIMRSLGGILVPIYFGALIDTTCMKWSTNSCGARGACRI 568
+L++R V+ E K LA+G M +R L + P+ G+ IDTTC+ W+ SCG R CR
Sbjct: 561 FMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDTTCVHWAL-SCGRRAVCRY 619
Query: 569 YNSTYLGRAFFGLKVALIFPVLVLLTVFIFVVRKKSHGKDTK 610
YN+ L F GL+ ++ + + V+R++ TK
Sbjct: 620 YNNDLLRNRFIGLQFFFKTGSVICFALVLAVLRQQDKEARTK 661
>gi|6005820 solute carrier organic anion transporter family, member
2B1 isoform 1 [Homo sapiens]
Length = 709
Score = 311 bits (797), Expect = 1e-84
Identities = 206/642 (32%), Positives = 316/642 (49%), Gaps = 59/642 (9%)
Query: 1 MKISTTQIERRFEISSSLVGLIDGSFEIGNLFVIVFVSYFGSKLHRPKLIGIGCFLMGTG 60
+K S + +E+RF +SS GL+ E+GN +IVFVSYFGS++HRP++IG G L+
Sbjct: 69 LKSSISTVEKRFGLSSQTSGLLASFNEVGNTALIVFVSYFGSRVHRPRMIGYGAILVALA 128
Query: 61 SILMALPHFFMGYYRYSKETNIDPSENSTSNL--PNCLINQMLSLNRTPSEIIERGCVKE 118
+LM LPHF YRY + D ++ ++L P N S E +
Sbjct: 129 GLLMTLPHFISEPYRYDNTSPEDMPQDFKASLCLPTTSAPASAPSNGNCSSYTETQHLSV 188
Query: 119 SGSHMWIYVFMGNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLGTVNVMGMTGLVFAFM 178
G +F+ L G+G PI P GISYIDDFA +S LYLG + + M G AF
Sbjct: 189 VG-----IMFVAQTLLGVGGVPIQPFGISYIDDFAHNSNSPLYLGILFAVTMMGPGLAFG 243
Query: 179 LGSLFAKMYVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGIVSIISSIPFFFLPLNPNK 238
LGSL ++YVDI + I +T KD RWVGAWWLGFL++ +++IP+FF P
Sbjct: 244 LGSLMLRLYVDINQMPEGGISLTIKDPRWVGAWWLGFLIAAGAVALAAIPYFFFP--KEM 301
Query: 239 PQKERKVSLFLHVL-----------------------KTNDKRNQIA-NLTNRRKYITKN 274
P+++R++ VL K D QIA NLT + +
Sbjct: 302 PKEKRELQFRRKVLAVTDSPARKGKDSPSKQSPGESTKKQDGLVQIAPNLT-----VIQF 356
Query: 275 VTGFFQSLKSILTNPLYVIFVIFTLLHMSSYIASLTYIIKMVEQQYGWSASKTNFLLGVL 334
+ F + L L +P++++ V+ + S T++ K +E+Q+ +AS N L+G L
Sbjct: 357 IKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAGMATFLPKFLERQFSITASYANLLIGCL 416
Query: 335 ALPAVAIGMFSGGYIIKKFKLSLVGLAKLAFCSATVHLLSQVLYFFLICESKSVAGLTLT 394
+ P+V +G+ GG ++K+ L VG L + L + FF+ C S +AG+T
Sbjct: 417 SFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLGMLLCLFFSLPLFFIGCSSHQIAGIT-- 474
Query: 395 YDGNSPVRSHVDVPLS-YCNSECNCDESQWEPVCG-NNGITYLSPCLAGCKS----SSGN 448
+H + LS C C+C + PVC + + Y++PC AGC S + +
Sbjct: 475 ----HQTSAHPGLELSPSCMEACSCPLDGFNPVCDPSTRVEYITPCHAGCSSWVVQDALD 530
Query: 449 KEPIVFYNCSCVEVIGLQNKNYSAHLGECPRDDACTRKSYVYFVIQVLDAFLCAVGLTSY 508
+ + NCSCV + G C D C+ + ++ L + L + T
Sbjct: 531 NSQVFYTNCSCVV------EGNPVLAGSC--DSTCSHLVVPFLLLVSLGSALACLTHTPS 582
Query: 509 SVLVIRIVQPELKALAIGFHSMIMRSLGGILVPIYFGALIDTTCMKWSTNSCGARGACRI 568
+L++R V+ E K LA+G M +R L + P+ G+ IDTTC+ W+ SCG R CR
Sbjct: 583 FMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDTTCVHWAL-SCGRRAVCRY 641
Query: 569 YNSTYLGRAFFGLKVALIFPVLVLLTVFIFVVRKKSHGKDTK 610
YN+ L F GL+ ++ + + V+R++ TK
Sbjct: 642 YNNDLLRNRFIGLQFFFKTGSVICFALVLAVLRQQDKEARTK 683
>gi|225637473 solute carrier organic anion transporter family,
member 5A1 isoform 1 [Homo sapiens]
Length = 848
Score = 307 bits (787), Expect = 2e-83
Identities = 207/635 (32%), Positives = 318/635 (50%), Gaps = 56/635 (8%)
Query: 6 TQIERRFEISSSLVGLIDGSFEIGNLFVIVFVSYFGSKLHRPKLIGIGCFLMGTGSILMA 65
T IERR+ + SS GL+ F+IGNL V+VFVSYFG + RP + +G L+ G+ L A
Sbjct: 154 TTIERRYSLKSSESGLLVSCFDIGNLVVVVFVSYFGGRGRRPLWLAVGGLLIAFGAALFA 213
Query: 66 LPHFFMGYYRYSKETNIDPSENSTSNLPNCLINQMLSLNRTPSEIIERGCVKESG-SHMW 124
LPHF Y+ + P++ + + + C K+SG ++ W
Sbjct: 214 LPHFISPPYQIQELNASAPNDGLCQG------------GNSTATLEPPACPKDSGGNNHW 261
Query: 125 IYVFM---GNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLGTVNVMGMTGLVFAFMLGS 181
+YV + +L G+G TPI LG +Y+DD K+ +SSLYL + VMG G ++LG
Sbjct: 262 VYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLAIMYVMGALGPAVGYLLGG 321
Query: 182 LFAKMYVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGIVSIISSIPFFFLP--LNP-NK 238
L YVD + + + D R++G WW GFL+ I + P F P L P +K
Sbjct: 322 LLIGFYVD----PRNPVHLDQNDPRFIGNWWSGFLLCAIAMFLVIFPMFTFPKKLPPRHK 377
Query: 239 PQKERKVSLFL----HVLKTNDKRNQIANLTNRRKYITKNVTGFFQSLKSILTNPLYVIF 294
+K++K S+ VLK ++ A+ K+V ++ IL+N ++
Sbjct: 378 KKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKDVRDLPRAAVRILSNMTFLFV 437
Query: 295 VIFTLLHMSSYIASLTYIIKMVEQQYGWSASKTNFLLGVLALPAVAIGMFSGGYIIKKFK 354
+ + A +T+I K +E Q+G AS + GV+ +P+ +G+ GGYIIKK K
Sbjct: 438 SLSYTAESAIVTAFITFIPKFIESQFGIPASNASIYTGVIIVPSAGVGIVLGGYIIKKLK 497
Query: 355 LSLVGLAKLAFCSATVHLLSQVLYFFLICESKSVAGLTLTY-DGNSPVRSHVDVPLSYCN 413
L AKLA + V LL F + CES ++ G+ + Y G S H ++ S CN
Sbjct: 498 LGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTTGPSLTMPHRNLTGS-CN 556
Query: 414 SECNCDESQWEPVCGNNGITYLSPCLAGCKSSSGNKEPIVFY-NCSCVE--------VIG 464
C C ++EPVCG++GITY +PCLAGC +S I Y C+CV+ +G
Sbjct: 557 VNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTECTCVQSRQVITPPTVG 616
Query: 465 LQ------------NKNYSAHLGECPRDDACTRKSYVYFVIQV-LDAFLCAVGLTSYSVL 511
+ N+N A G+C R T + + F++ + + F+ A S ++
Sbjct: 617 QRSQLRVVIVKTYLNENGYAVSGKCKR----TCNTLIPFLVFLFIVTFITACAQPSAIIV 672
Query: 512 VIRIVQPELKALAIGFHSMIMRSLGGILVPIYFGALIDTTCMKWSTNSCGARGACRIYNS 571
+R V+ E + A+G +++R+L I PIYFGA+IDTTCM W CG +G+C YN
Sbjct: 673 TLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGAVIDTTCMLWQ-QECGVQGSCWEYNV 731
Query: 572 TYLGRAFFGLKVALIFPVLVLLTVFIFVVRKKSHG 606
T +FGL L F + + + + ++ K G
Sbjct: 732 TSFRFVYFGLAAGLKFVGFIFIFLAWYSIKYKEDG 766
>gi|38679890 solute carrier organic anion transporter family, member
4C1 [Homo sapiens]
Length = 724
Score = 303 bits (776), Expect = 3e-82
Identities = 177/592 (29%), Positives = 299/592 (50%), Gaps = 53/592 (8%)
Query: 1 MKISTTQIERRFEISSSLVGLIDGSFEIGNLFVIVFVSYFGSKLHRPKLIGIGCFLMGTG 60
+ IS + +E+R+E+ SSL GLI S++I + +FVS+FG + H+P+ + F++G G
Sbjct: 126 VNISISTVEKRYEMKSSLTGLISSSYDISFCLLSLFVSFFGERGHKPRWLAFAAFMIGLG 185
Query: 61 SILMALPHFFMGYYRYSK--ETNIDPSENSTSNLPNCLINQMLSLNRTPSEIIERGCVKE 118
+++ +LP FF G Y+ E + NSTS C
Sbjct: 186 ALVFSLPQFFSGEYKLGSLFEDTCVTTRNSTS------------------------CTSS 221
Query: 119 SGS-HMWIYVF-MGNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLGTVNVMGMTGLVFA 176
+ S ++YVF +G +L G G TP+ LG +++DD SSLY+GT M + G
Sbjct: 222 TSSLSNYLYVFILGQLLLGAGGTPLYTLGTAFLDDSVPTHKSSLYIGTGYAMSILGPAIG 281
Query: 177 FMLGSLFAKMYVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGIVSIISSIPFFFLPLNP 236
++LG +Y+D+ + + +T D RW+GAWW+GFL+S I + IPF P
Sbjct: 282 YVLGGQLLTIYIDVAMGE--STDVTEDDPRWLGAWWIGFLLSWIFAWSLIIPFSCFP--- 336
Query: 237 NKPQKERKVSLFLHVLKTNDKRNQIANLTNRRKYITKNVTGFFQSLKSILTNPLYVIFVI 296
K + + KT+ +N + K++ F +LK+++ N +++ V+
Sbjct: 337 ----KHLPGTAEIQAGKTSQAHQSNSNADVK---FGKSIKDFPAALKNLMKNAVFMCLVL 389
Query: 297 FTLLHMSSYIASLTYIIKMVEQQYGWSASKTNFLLGVLALPAVAIGMFSGGYIIKKFKLS 356
T T++ K +E Q+G ++S L G + +P A+G GG+++ KF+++
Sbjct: 390 STSSEALITTGFATFLPKFIENQFGLTSSFAATLGGAVLIPGAALGQILGGFLVSKFRMT 449
Query: 357 LVGLAKLAFCSATVHLLSQVLYFFLICESKSVAGLTLTYDGNSPVRSHVDVPLSYCNSEC 416
K A ++ V L ++ + CE++ AG++ +Y+G + + + + CN+ C
Sbjct: 450 CKNTMKFALFTSGVALTLSFVFMYAKCENEPFAGVSESYNGTGELGNLI----APCNANC 505
Query: 417 NCDESQWEPVCGNNGITYLSPCLAGCKSSSGNKEPIVFYNCSCVE-----VIGLQNKNYS 471
NC S + PVCG +G+ Y SPC AGC + +++P V+YNCSC+E + +
Sbjct: 506 NCSRSYYYPVCG-DGVQYFSPCFAGCSNPVAHRKPKVYYNCSCIERKTEITSTAETFGFE 564
Query: 472 AHLGECPRDDACTRKSYVYFVIQVLDAFLCAVGLTSYSVLVIRIVQPELKALAIGFHSMI 531
A G+C A F I ++ F+ +T V ++R V ++LA+G M+
Sbjct: 565 AKAGKCETHCAKLPIFLCIFFIVIIFTFMAGTPIT---VSILRCVNHRQRSLALGIQFMV 621
Query: 532 MRSLGGILVPIYFGALIDTTCMKWSTNSCGARGACRIYNSTYLGRAFFGLKV 583
+R LG I PI FG ID+TC+ W N CG +GAC IY++ + + V
Sbjct: 622 LRLLGTIPGPIIFGFTIDSTCILWDINDCGIKGACWIYDNIKMAHMLVAISV 673
>gi|225637475 solute carrier organic anion transporter family,
member 5A1 isoform 3 [Homo sapiens]
Length = 793
Score = 271 bits (693), Expect = 1e-72
Identities = 190/629 (30%), Positives = 296/629 (47%), Gaps = 99/629 (15%)
Query: 6 TQIERRFEISSSLVGLIDGSFEIGNLFVIVFVSYFGSKLHRPKLIGIGCFLMGTGSILMA 65
T IERR+ + SS GL+ F+IGNL V+VFVSYFG + RP + +G L+ G+ L A
Sbjct: 154 TTIERRYSLKSSESGLLVSCFDIGNLVVVVFVSYFGGRGRRPLWLAVGGLLIAFGAALFA 213
Query: 66 LPHFFMGYYRYSKETNIDPSENSTSNLPNCLINQMLSLNRTPSEIIERGCVKESG-SHMW 124
LPHF Y+ + P++ + + + C K+SG ++ W
Sbjct: 214 LPHFISPPYQIQELNASAPNDGLCQG------------GNSTATLEPPACPKDSGGNNHW 261
Query: 125 IYVFM---GNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLGTVNVMGMTGLVFAFMLGS 181
+YV + +L G+G TPI LG +Y+DD K+ +SSLYL + VMG G ++LG
Sbjct: 262 VYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLAIMYVMGALGPAVGYLLGG 321
Query: 182 LFAKMYVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGIVSIISSIPFFFLPLN-PNKPQ 240
L YVD + + + D R++G WW GFL+ I + P F P P + +
Sbjct: 322 LLIGFYVD----PRNPVHLDQNDPRFIGNWWSGFLLCAIAMFLVIFPMFTFPKKLPPRHK 377
Query: 241 KERKVSLFLHVLKTNDKRNQIANLTNRRKYITKNVTGFFQSLKSILTNPLYVIFVIFTLL 300
K++K + + +D + +N + + ++ GF + ++
Sbjct: 378 KKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSM-GFGKDVR----------------- 419
Query: 301 HMSSYIASLTYIIKMVEQQYGWSASKTNFLLGVLALPAVAIGMFSGGYIIKKFKLSLVGL 360
GV+ +P+ +G+ GGYIIKK KL
Sbjct: 420 -------------------------------GVIIVPSAGVGIVLGGYIIKKLKLGARES 448
Query: 361 AKLAFCSATVHLLSQVLYFFLICESKSVAGLTLTYD-GNSPVRSHVDVPLSYCNSECNCD 419
AKLA + V LL F + CES ++ G+ + Y G S H ++ S CN C C
Sbjct: 449 AKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTTGPSLTMPHRNLTGS-CNVNCGCK 507
Query: 420 ESQWEPVCGNNGITYLSPCLAGCKSSSGNKEPIVFY-NCSCVE--------VIGLQ---- 466
++EPVCG++GITY +PCLAGC +S I Y C+CV+ +G +
Sbjct: 508 IHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTECTCVQSRQVITPPTVGQRSQLR 567
Query: 467 --------NKNYSAHLGECPRDDACTRKSYVYFVIQV-LDAFLCAVGLTSYSVLVIRIVQ 517
N+N A G+C R T + + F++ + + F+ A S ++ +R V+
Sbjct: 568 VVIVKTYLNENGYAVSGKCKR----TCNTLIPFLVFLFIVTFITACAQPSAIIVTLRSVE 623
Query: 518 PELKALAIGFHSMIMRSLGGILVPIYFGALIDTTCMKWSTNSCGARGACRIYNSTYLGRA 577
E + A+G +++R+L I PIYFGA+IDTTCM W CG +G+C YN T
Sbjct: 624 DEERPFALGMQFVLLRTLAYIPTPIYFGAVIDTTCMLWQ-QECGVQGSCWEYNVTSFRFV 682
Query: 578 FFGLKVALIFPVLVLLTVFIFVVRKKSHG 606
+FGL L F + + + + ++ K G
Sbjct: 683 YFGLAAGLKFVGFIFIFLAWYSIKYKEDG 711
>gi|39777594 solute carrier organic anion transporter family member
4A1 [Homo sapiens]
Length = 722
Score = 264 bits (674), Expect = 2e-70
Identities = 183/616 (29%), Positives = 298/616 (48%), Gaps = 60/616 (9%)
Query: 6 TQIERRFEISSSLVGLIDGSFEIGNLFVIVFVSYFGSKLHRPKLIGIGCFLMGTGSILMA 65
T +ERR+++ S GLI S++I + FVSYFG H+P+ +G G LMGTGS++ A
Sbjct: 129 TSLERRYDLHSYQSGLIASSYDIAACLCLTFVSYFGGSGHKPRWLGWGVLLMGTGSLVFA 188
Query: 66 LPHFFMGYYRYSKETNIDPSENSTSNLPNCLINQMLSLNRTPSEIIERGCVKESGSHMWI 125
LPHF G Y E +D + P + SG +
Sbjct: 189 LPHFTAGRY----EVELDAGVRTCPANPGAVCAD-----------------STSGLSRYQ 227
Query: 126 YVFM-GNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLGTVNVMGMTGLVFAFMLGSLFA 184
VFM G L G+G TP+ LG++Y+D+ K S +Y+ + G +++G
Sbjct: 228 LVFMLGQFLHGVGATPLYTLGVTYLDENVKSSCSPVYIAIFYTAAILGPAAGYLIGGALL 287
Query: 185 KMYVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGIVSIISSIPFFFLPLN-PNKPQKER 243
+Y ++G +T + WVGAWW+GFL SG + +++P P P +
Sbjct: 288 NIYTEMG----RRTELTTESPLWVGAWWVGFLGSGAAAFFTAVPILGYPRQLPGSQRYAV 343
Query: 244 KVSLFLHVLKTNDKRNQIANLTNRRKYITKNVTGFFQSLKSILTNPLYVIFVIFTLLHMS 303
+ +H LK + R + +N K + S+ +L NP +++ + +
Sbjct: 344 MRAAEMHQLK-DSSRGEASN-----PDFGKTIRDLPLSIWLLLKNPTFILLCLAGATEAT 397
Query: 304 SYIASLTYIIKMVEQQYGWSASKTNFLLGVLALPAVAIGMFSGGYIIKKFKLSLVGLAKL 363
T+ K +E Q+ SAS+ L G L +PA G F GG+ + K +L G A +
Sbjct: 398 LITGMSTFSPKFLESQFSLSASEAATLFGYLVVPAGGGGTFLGGFFVNKLRLR--GSAVI 455
Query: 364 AFC-SATVHLLSQVLYFFLICESKSVAGLTLTYDGNSPVRSHVDVPLSYCNSECNCDESQ 422
FC TV L +L F L C S +AG+T +Y G+ H+++ + CN+ C+C
Sbjct: 456 KFCLFCTVVSLLGILVFSLHCPSVPMAGVTASYGGSLLPEGHLNL-TAPCNAACSCQPEH 514
Query: 423 WEPVCGNNGITYLSPCLAGCKSSS-----GNKEPIVFYNCSCVEVIGLQNKNYSAHLGEC 477
+ PVCG++G+ Y S C AGC +++ G K V+ +CSC+ L + A G+C
Sbjct: 515 YSPVCGSDGLMYFSLCHAGCPAATETNVDGQK---VYRDCSCIPQ-NLSSGFGHATAGKC 570
Query: 478 PRDDACTRKS--YVYFVIQVLDAFLCAV-GLTSYSVLVIRIVQPELKALAIGFHSMIMRS 534
C RK V+ + + FL ++ LT+ +R V+ ++ A+G +++R
Sbjct: 571 --TSTCQRKPLLLVFIFVVIFFTFLSSIPALTA----TLRCVRDPQRSFALGIQWIVVRI 624
Query: 535 LGGILVPIYFGALIDTTCMKWSTNSCGARGACRIYNSTYLGRAFFGLKVALIFPVLVLL- 593
LGGI PI FG +ID C+ W + CG +G+C +Y ++ + R + L + L++ VL +L
Sbjct: 625 LGGIPGPIAFGWVIDKACLLWQ-DQCGQQGSCLVYQNSAMSR--YILIMGLLYKVLGVLF 681
Query: 594 -TVFIFVVRKKSHGKD 608
+ F+ + S D
Sbjct: 682 FAIACFLYKPLSESSD 697
>gi|225637477 solute carrier organic anion transporter family,
member 5A1 isoform 2 [Homo sapiens]
Length = 687
Score = 247 bits (631), Expect = 2e-65
Identities = 160/469 (34%), Positives = 240/469 (51%), Gaps = 30/469 (6%)
Query: 6 TQIERRFEISSSLVGLIDGSFEIGNLFVIVFVSYFGSKLHRPKLIGIGCFLMGTGSILMA 65
T IERR+ + SS GL+ F+IGNL V+VFVSYFG + RP + +G L+ G+ L A
Sbjct: 154 TTIERRYSLKSSESGLLVSCFDIGNLVVVVFVSYFGGRGRRPLWLAVGGLLIAFGAALFA 213
Query: 66 LPHFFMGYYRYSKETNIDPSENSTSNLPNCLINQMLSLNRTPSEIIERGCVKESG-SHMW 124
LPHF Y+ + P++ + + + C K+SG ++ W
Sbjct: 214 LPHFISPPYQIQELNASAPNDGLCQG------------GNSTATLEPPACPKDSGGNNHW 261
Query: 125 IYVFM---GNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLGTVNVMGMTGLVFAFMLGS 181
+YV + +L G+G TPI LG +Y+DD K+ +SSLYL + VMG G ++LG
Sbjct: 262 VYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLAIMYVMGALGPAVGYLLGG 321
Query: 182 LFAKMYVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGIVSIISSIPFFFLP--LNP-NK 238
L YVD + + + D R++G WW GFL+ I + P F P L P +K
Sbjct: 322 LLIGFYVD----PRNPVHLDQNDPRFIGNWWSGFLLCAIAMFLVIFPMFTFPKKLPPRHK 377
Query: 239 PQKERKVSLFL----HVLKTNDKRNQIANLTNRRKYITKNVTGFFQSLKSILTNPLYVIF 294
+K++K S+ VLK ++ A+ K+V ++ IL+N ++
Sbjct: 378 KKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKDVRDLPRAAVRILSNMTFLFV 437
Query: 295 VIFTLLHMSSYIASLTYIIKMVEQQYGWSASKTNFLLGVLALPAVAIGMFSGGYIIKKFK 354
+ + A +T+I K +E Q+G AS + GV+ +P+ +G+ GGYIIKK K
Sbjct: 438 SLSYTAESAIVTAFITFIPKFIESQFGIPASNASIYTGVIIVPSAGVGIVLGGYIIKKLK 497
Query: 355 LSLVGLAKLAFCSATVHLLSQVLYFFLICESKSVAGLTLTY-DGNSPVRSHVDVPLSYCN 413
L AKLA + V LL F + CES ++ G+ + Y G S H ++ S CN
Sbjct: 498 LGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTTGPSLTMPHRNLTGS-CN 556
Query: 414 SECNCDESQWEPVCGNNGITYLSPCLAGCKSSSGNKEPIVFY-NCSCVE 461
C C ++EPVCG++GITY +PCLAGC +S I Y C+CV+
Sbjct: 557 VNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTECTCVQ 605
>gi|223634014 solute carrier organic anion transporter family,
member 2B1 isoform 3 [Homo sapiens]
Length = 565
Score = 245 bits (626), Expect = 8e-65
Identities = 162/514 (31%), Positives = 252/514 (49%), Gaps = 52/514 (10%)
Query: 127 VFMGNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLGTVNVMGMTGLVFAFMLGSLFAKM 186
+F+ L G+G PI P GISYIDDFA +S LYLG + + M G AF LGSL ++
Sbjct: 48 MFVAQTLLGVGGVPIQPFGISYIDDFAHNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRL 107
Query: 187 YVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGIVSIISSIPFFFLPLNPNKPQKERKVS 246
YVDI + I +T KD RWVGAWWLGFL++ +++IP+FF P P+++R++
Sbjct: 108 YVDINQMPEGGISLTIKDPRWVGAWWLGFLIAAGAVALAAIPYFFFP--KEMPKEKRELQ 165
Query: 247 LFLHVL-----------------------KTNDKRNQIA-NLTNRRKYITKNVTGFFQSL 282
VL K D QIA NLT + + + F + L
Sbjct: 166 FRRKVLAVTDSPARKGKDSPSKQSPGESTKKQDGLVQIAPNLT-----VIQFIKVFPRVL 220
Query: 283 KSILTNPLYVIFVIFTLLHMSSYIASLTYIIKMVEQQYGWSASKTNFLLGVLALPAVAIG 342
L +P++++ V+ + S T++ K +E+Q+ +AS N L+G L+ P+V +G
Sbjct: 221 LQTLRHPIFLLVVLSQVCLSSMAAGMATFLPKFLERQFSITASYANLLIGCLSFPSVIVG 280
Query: 343 MFSGGYIIKKFKLSLVGLAKLAFCSATVHLLSQVLYFFLICESKSVAGLTLTYDGNSPVR 402
+ GG ++K+ L VG L + L + FF+ C S +AG+T
Sbjct: 281 IVVGGVLVKRLHLGPVGCGALCLLGMLLCLFFSLPLFFIGCSSHQIAGIT------HQTS 334
Query: 403 SHVDVPLS-YCNSECNCDESQWEPVCG-NNGITYLSPCLAGCKS----SSGNKEPIVFYN 456
+H + LS C C+C + PVC + + Y++PC AGC S + + + + N
Sbjct: 335 AHPGLELSPSCMEACSCPLDGFNPVCDPSTRVEYITPCHAGCSSWVVQDALDNSQVFYTN 394
Query: 457 CSCVEVIGLQNKNYSAHLGECPRDDACTRKSYVYFVIQVLDAFLCAVGLTSYSVLVIRIV 516
CSCV + G C D C+ + ++ L + L + T +L++R V
Sbjct: 395 CSCVV------EGNPVLAGSC--DSTCSHLVVPFLLLVSLGSALACLTHTPSFMLILRGV 446
Query: 517 QPELKALAIGFHSMIMRSLGGILVPIYFGALIDTTCMKWSTNSCGARGACRIYNSTYLGR 576
+ E K LA+G M +R L + P+ G+ IDTTC+ W+ SCG R CR YN+ L
Sbjct: 447 KKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDTTCVHWAL-SCGRRAVCRYYNNDLLRN 505
Query: 577 AFFGLKVALIFPVLVLLTVFIFVVRKKSHGKDTK 610
F GL+ ++ + + V+R++ TK
Sbjct: 506 RFIGLQFFFKTGSVICFALVLAVLRQQDKEARTK 539
>gi|93277099 solute carrier organic anion transporter family, member
6A1 [Homo sapiens]
Length = 719
Score = 187 bits (475), Expect = 3e-47
Identities = 145/612 (23%), Positives = 261/612 (42%), Gaps = 56/612 (9%)
Query: 3 ISTTQIERRFEISSSLVGLIDGSFEIGNLFVIVFVSYFGSKLHRPKLIGI--GCFLMGTG 60
+S ++ +++ + ++ S++I + V +F++++G R K+I FL+G G
Sbjct: 128 VSIGDFQKEYQLKTIEKLALEKSYDISSGLVAIFIAFYGD---RKKVIWFVASSFLIGLG 184
Query: 61 SILMALPHFFMGYYRYSKETNIDPSENSTSNLPNCLINQMLSLNRTPSEI-IERGCVKES 119
S+L A P EN S + + EI + GC
Sbjct: 185 SLLCAFPSI--------------NEENKQSKV---------GIEDICEEIKVVSGCQSSG 221
Query: 120 GSHMWIYV---FMGNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLGTVNVMGMTGLVFA 176
S Y+ +G ++GI P+ LGI++ID+ + +YLG M G
Sbjct: 222 ISFQSKYLSFFILGQTVQGIAGMPLYILGITFIDENVATHSAGIYLGIAECTSMIGYALG 281
Query: 177 FMLGSLFAKMYVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGIVSIISSIPFFFLPLNP 236
++LG+ K V + + W+ WW+ FL + +V+ + IP P
Sbjct: 282 YVLGAPLVK--VPENTTSATNTTVNNGSPEWLWTWWINFLFAAVVAWCTLIPLSCFP--N 337
Query: 237 NKPQKERKVSLFLHVLKTNDKRNQIANLTNRRKYIT--KNVTGFFQSLKSILTNPLYVIF 294
N P R +K KR Q+ +R K + N+ +L ++ NP+ +
Sbjct: 338 NMPGSTR--------IKAR-KRKQLHFFDSRLKDLKLGTNIKDLCAALWILMKNPVLICL 388
Query: 295 VIFTLLHMSSYIASLTYIIKMVEQQYGWSASKTNFLLGVLALPAVAIGMFSGGYIIKKFK 354
+ I + ++ +E Q+ + + L G++ +P A+G GG I+ +
Sbjct: 389 ALSKATEYLVIIGASEFLPIYLENQFILTPTVATTLAGLVLIPGGALGQLLGGVIVSTLE 448
Query: 355 LSLVGLAKLAFCSATVHLLSQVLYFFLICESKSVAGLTLTYDGNSPVRSHVDVPLSYCNS 414
+S L + ++ + L+ V F+ C AG+ YDG + ++ P CN
Sbjct: 449 MSCKALMRFIMVTSVISLILLVFIIFVRCNPVQFAGINEDYDGTGKL-GNLTAP---CNE 504
Query: 415 ECNCDESQWEPVCGNNGITYLSPCLAGCKSSSGNKEPIVFYNCSCVEVIGLQNKNYSAHL 474
+C C S + +CG + I Y SPC AGC S + ++YNCSC++ GL +
Sbjct: 505 KCRCSSSIYSSICGRDDIEYFSPCFAGCTYSKAQNQKKMYYNCSCIKE-GLITADAEGDF 563
Query: 475 GECPRDDACTRKSY-VYFVIQVLDAFLCAVGLTSYSVL--VIRIVQPELKALAIGFHSMI 531
+ R C K Y + I + + L G + ++ + R+V +L++LA+G +I
Sbjct: 564 IDA-RPGKCDAKCYKLPLFIAFIFSTLIFSGFSGVPIVLAMTRVVPDKLRSLALGVSYVI 622
Query: 532 MRSLGGILVPIYFGALIDTTCMKWSTNSCGARGACRIYNSTYLGRAFFGLKVALIFPVLV 591
+R G I P F +T+C+ N CG G C IYN T + G+ ++
Sbjct: 623 LRIFGTIPGPSIFKMSGETSCILRDVNKCGHTGRCWIYNKTKMAFLLVGICFLCKLCTII 682
Query: 592 LLTVFIFVVRKK 603
T+ F+ +++
Sbjct: 683 FTTIAFFIYKRR 694
>gi|11863156 RECK protein precursor [Homo sapiens]
Length = 971
Score = 38.1 bits (87), Expect = 0.025
Identities = 23/68 (33%), Positives = 29/68 (42%), Gaps = 23/68 (33%)
Query: 416 CNCDESQWEPVCGNNGITYLSPCLAGCKSSSGNKEPIVFYNCSCVEVIGLQNKNYSAHLG 475
CNC + Q+ PVCG NG TY S C+A C +GLQ+ + G
Sbjct: 633 CNCAD-QFVPVCGQNGRTYPSACIARC--------------------VGLQDHQF--EFG 669
Query: 476 ECPRDDAC 483
C D C
Sbjct: 670 SCMSKDPC 677
Score = 30.0 bits (66), Expect = 6.8
Identities = 18/56 (32%), Positives = 27/56 (48%), Gaps = 6/56 (10%)
Query: 424 EPVCGNNGITYLSPCLAGCKSSSGNKEPIVFY-NCSCVEVIGLQNKNYSAHLGECP 478
EPVCG+NG TY S C A ++ + +Y +C V V+ + +CP
Sbjct: 758 EPVCGHNGETYSSVCAA-----YSDRVAVDYYGDCQAVGVLSEHSSVAECASVKCP 808
>gi|47679099 Kazal type serine protease inhibitor 5-like 2 [Homo
sapiens]
Length = 97
Score = 35.0 bits (79), Expect = 0.21
Identities = 19/50 (38%), Positives = 27/50 (54%), Gaps = 1/50 (2%)
Query: 407 VPLSYCNSECNCDESQWEPVCGNNGITYLSPCLAGCKSSSGNKEPIVFYN 456
V LS+ N N ++P+CG N ITY +PC+ C S + I FY+
Sbjct: 45 VNLSWYNGTVNPCPGLYQPICGTNFITYDNPCIL-CVESLKSHGRIRFYH 93
>gi|66082554 low density lipoprotein receptor-related protein 8
isoform 2 precursor [Homo sapiens]
Length = 793
Score = 33.5 bits (75), Expect = 0.62
Identities = 24/87 (27%), Positives = 40/87 (45%), Gaps = 10/87 (11%)
Query: 403 SHVDVPLSY-CNSECNCDESQWEPVCGNNGITYLSPCL---AGCKSSSGNKEPIVFYNCS 458
SH VP S+ C+ E +C+ E C T+L+ CL GC + + + + C+
Sbjct: 138 SHKCVPASWRCDGEKDCEGGADEAGCA----TWLNECLHNNGGCSHICTDLK--IGFECT 191
Query: 459 CVEVIGLQNKNYSAHLGECPRDDACTR 485
C L ++ + EC DAC++
Sbjct: 192 CPAGFQLLDQKTCGDIDECKDPDACSQ 218
>gi|41327156 solute carrier family 16 (monocarboxylic acid
transporters), member 14 [Homo sapiens]
Length = 510
Score = 33.1 bits (74), Expect = 0.81
Identities = 52/229 (22%), Positives = 92/229 (40%), Gaps = 23/229 (10%)
Query: 243 RKVSLFLHVLKTNDKRNQIANLTNR-RKYITKNVTGFFQSLKSILTNPLYVIFVIFTLLH 301
RK L +LKT ++ LT R RK +G+F + S+ TN ++V F+ + L
Sbjct: 274 RKNMCALRILKT------VSWLTMRVRKGFEDWYSGYFGTA-SLFTNRMFVAFIFWALFA 326
Query: 302 MSSYIASLTYIIKMVEQQYGWSASKTNF-LLGVLAL----PAVAIGMFSGGYIIKKFKLS 356
SS++ ++ ++V Y S F L ++A+ V +G+ + I + +
Sbjct: 327 YSSFVIPFIHLPEIV-NLYNLSEQNDVFPLTSIIAIVHIFGKVILGVIADLPCISVWNVF 385
Query: 357 LVGLAKLAFCSATVHLLSQVLYFFLICESKSVAGLTLTYDGNSPVRSHVDVPLSYCNSEC 416
L+ L + L+ +IC ++ G + Y PV + V + + +
Sbjct: 386 LLANFTLVLSIFILPLMHTYAGLAVIC---ALIGFSSGYFSLMPVVTEDLVGIEHLANAY 442
Query: 417 NCDESQWEPVCGNNGITYLSPCLAGCKSSSGNKEPIVFYNCSCVEVIGL 465
+C N L P AG K FY C + +IG+
Sbjct: 443 GI------IICANGISALLGPPFAGWIYDITQKYDFSFYICGLLYMIGI 485
>gi|12383051 transmembrane protein with EGF-like and two
follistatin-like domains 2 [Homo sapiens]
Length = 374
Score = 32.7 bits (73), Expect = 1.1
Identities = 22/62 (35%), Positives = 28/62 (45%), Gaps = 9/62 (14%)
Query: 406 DVPLSYCNSECNCDESQWEPVCGNNGITYLSPCL---AGCKSSSGNKEPIVFYNCSCVEV 462
D C +CN D + PVCG+NG +Y + C A CK S E +V SC
Sbjct: 85 DTVTCVCQFKCNND---YVPVCGSNGESYQNECYLRQAACKQQS---EILVVSEGSCATD 138
Query: 463 IG 464
G
Sbjct: 139 AG 140
>gi|54873613 agrin [Homo sapiens]
Length = 2045
Score = 32.0 bits (71), Expect = 1.8
Identities = 14/39 (35%), Positives = 21/39 (53%), Gaps = 3/39 (7%)
Query: 412 CNSECNCDESQWEPVCGNNGITYLSPC---LAGCKSSSG 447
C + +C PVCG++G+TY + C A C+S G
Sbjct: 703 CVCDFSCQSVPGSPVCGSDGVTYSTECELKKARCESQRG 741
Score = 29.6 bits (65), Expect = 8.9
Identities = 12/26 (46%), Positives = 18/26 (69%), Gaps = 3/26 (11%)
Query: 416 CNCDE---SQWEPVCGNNGITYLSPC 438
C C + S ++PVCG++G+TY S C
Sbjct: 488 CECLQACSSLYDPVCGSDGVTYGSAC 513
>gi|118600977 C3 and PZP-like, alpha-2-macroglobulin domain containing
8 [Homo sapiens]
Length = 1932
Score = 32.0 bits (71), Expect = 1.8
Identities = 14/39 (35%), Positives = 22/39 (56%), Gaps = 6/39 (15%)
Query: 414 SECNCDE---SQWEPVCGNNGITYLSPCL---AGCKSSS 446
+ C CD +Q PVCG++G+ Y S C A C+ ++
Sbjct: 1755 ARCGCDHDCGAQGNPVCGSDGVVYASACRLREAACRQAA 1793
>gi|13375930 suppressor of variegation 3-9 homolog 2 [Homo sapiens]
Length = 350
Score = 31.2 bits (69), Expect = 3.1
Identities = 30/107 (28%), Positives = 44/107 (41%), Gaps = 21/107 (19%)
Query: 348 YIIKKFK----LSLVGLAKLAFCSATVHLLSQVLYFFLICESKSVAGLTLTYDGNSPVRS 403
Y I ++K +SLV A CS T +F C ++ AG+ L Y+ N ++
Sbjct: 110 YYINEYKPAPGISLVNEATFG-CSCTD------CFFQKCCPAE--AGVLLAYNKNQQIKI 160
Query: 404 HVDVPLSYCNSECNCDESQWEPVCGNNGI---TYLSPCLAGCKSSSG 447
P+ CNS C C P C N + T S C+ + G
Sbjct: 161 PPGTPIYECNSRCQCG-----PDCPNRIVQKGTQYSLCIFRTSNGRG 202
>gi|218156275 hypothetical protein LOC374393 isoform b [Homo
sapiens]
Length = 704
Score = 30.8 bits (68), Expect = 4.0
Identities = 28/108 (25%), Positives = 48/108 (44%), Gaps = 7/108 (6%)
Query: 60 GSILMALP---HFFM--GYYRYSKETNIDPSENSTSNLPNCLINQMLSLNRTPSEIIERG 114
G L LP HF + G + SKE + N+ C++ ++++ RT +I++
Sbjct: 114 GMPLKCLPSDSHFKITFGQRKSSKEDGHILRQCENPNM-ECILFHVVAIGRTRKKIVKIN 172
Query: 115 CVKESGSHMWIYVFMGNMLRG-IGETPIVPLGISYIDDFAKEGHSSLY 161
+ E GS + IY G + G + + I + KEGH +Y
Sbjct: 173 ELHEKGSKLCIYALKGETIEGALCKDGRFRSDIGEFEWKLKEGHKKIY 220
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.140 0.425
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,441,687
Number of Sequences: 37866
Number of extensions: 992543
Number of successful extensions: 2767
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 29
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 2628
Number of HSP's gapped (non-prelim): 63
length of query: 640
length of database: 18,247,518
effective HSP length: 109
effective length of query: 531
effective length of database: 14,120,124
effective search space: 7497785844
effective search space used: 7497785844
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.