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Search of human proteins with 239746532
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239746532 PREDICTED: ankyrin repeat domain 60 [Homo sapiens]
(345 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239746532 PREDICTED: ankyrin repeat domain 60 [Homo sapiens] 702 0.0
gi|239757533 PREDICTED: ankyrin repeat domain 60 [Homo sapiens] 681 0.0
gi|239752049 PREDICTED: ankyrin repeat domain 60 [Homo sapiens] 681 0.0
gi|215598574 ankyrin 1 isoform 9 [Homo sapiens] 72 9e-13
gi|70780359 ankyrin 1 isoform 1 [Homo sapiens] 72 9e-13
gi|70780357 ankyrin 1 isoform 3 [Homo sapiens] 72 9e-13
gi|70780355 ankyrin 1 isoform 2 [Homo sapiens] 72 9e-13
gi|70780353 ankyrin 1 isoform 4 [Homo sapiens] 72 9e-13
gi|157743284 ankyrin repeat domain 52 [Homo sapiens] 62 1e-09
gi|188595682 ankyrin 2 isoform 3 [Homo sapiens] 61 1e-09
gi|52426737 ankyrin 2 isoform 2 [Homo sapiens] 61 1e-09
gi|52426735 ankyrin 2 isoform 1 [Homo sapiens] 61 1e-09
gi|62988328 ankyrin repeat domain 50 [Homo sapiens] 60 2e-09
gi|32967601 ankyrin 3 isoform 1 [Homo sapiens] 60 3e-09
gi|92087060 ankyrin repeat and SOCS box-containing 15 [Homo sapi... 60 4e-09
gi|68131557 ankyrin repeat domain 28 [Homo sapiens] 59 8e-09
gi|169403959 ankyrin repeat domain 53 isoform a [Homo sapiens] 59 8e-09
gi|169403957 ankyrin repeat domain 53 isoform b [Homo sapiens] 59 8e-09
gi|55741641 kinase D-interacting substrate of 220 kDa [Homo sapi... 57 2e-08
gi|20270347 ankyrin repeat domain 54 [Homo sapiens] 57 3e-08
gi|52486194 phospholipase A2, group VI isoform a [Homo sapiens] 56 4e-08
gi|56676397 ankyrin repeat domain 11 [Homo sapiens] 55 7e-08
gi|215598824 ankyrin repeat and SOCS box-containing 10 isoform 2... 55 7e-08
gi|215598819 ankyrin repeat and SOCS box-containing 10 isoform 1... 55 7e-08
gi|8051593 GA binding protein transcription factor, beta subunit... 55 7e-08
gi|8051595 GA binding protein transcription factor, beta subunit... 55 7e-08
gi|32483404 GA binding protein transcription factor, beta subuni... 55 7e-08
gi|8051597 GA binding protein transcription factor, beta subunit... 55 7e-08
gi|8051599 GA binding protein transcription factor, beta subunit... 55 7e-08
gi|156142184 ankyrin repeat domain 39 [Homo sapiens] 55 7e-08
>gi|239746532 PREDICTED: ankyrin repeat domain 60 [Homo sapiens]
Length = 345
Score = 702 bits (1811), Expect = 0.0
Identities = 345/345 (100%), Positives = 345/345 (100%)
Query: 1 MTRGRAWGMRRAAAGAGGARAAGPTGGASRLHPNAGRRSGARAGAQGCGGPRVGSADSRA 60
MTRGRAWGMRRAAAGAGGARAAGPTGGASRLHPNAGRRSGARAGAQGCGGPRVGSADSRA
Sbjct: 1 MTRGRAWGMRRAAAGAGGARAAGPTGGASRLHPNAGRRSGARAGAQGCGGPRVGSADSRA 60
Query: 61 LPAQPLACARGRSQRLVCDPKAASALPDLAPDVFVLRVRLEETGEMFRVANCRGDMTVRE 120
LPAQPLACARGRSQRLVCDPKAASALPDLAPDVFVLRVRLEETGEMFRVANCRGDMTVRE
Sbjct: 61 LPAQPLACARGRSQRLVCDPKAASALPDLAPDVFVLRVRLEETGEMFRVANCRGDMTVRE 120
Query: 121 LKEELDLMVGIPFNLQRLQYLDEGVLMDDTTLKFHDVVPGGIISLCIWHHDGWTELVLAA 180
LKEELDLMVGIPFNLQRLQYLDEGVLMDDTTLKFHDVVPGGIISLCIWHHDGWTELVLAA
Sbjct: 121 LKEELDLMVGIPFNLQRLQYLDEGVLMDDTTLKFHDVVPGGIISLCIWHHDGWTELVLAA 180
Query: 181 VEGDPSKLSCLGLTEDSFYRTANSEHFEGEKWKHWTSQRAFVALYVASHRGHFDAVQYLL 240
VEGDPSKLSCLGLTEDSFYRTANSEHFEGEKWKHWTSQRAFVALYVASHRGHFDAVQYLL
Sbjct: 181 VEGDPSKLSCLGLTEDSFYRTANSEHFEGEKWKHWTSQRAFVALYVASHRGHFDAVQYLL 240
Query: 241 EHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRDAKGETPISIAHRLNHTL 300
EHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRDAKGETPISIAHRLNHTL
Sbjct: 241 EHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRDAKGETPISIAHRLNHTL 300
Query: 301 SERQMVLLHRIAKSGIRDLNDLVMKNALQRVKSGFRSEKMTMTPH 345
SERQMVLLHRIAKSGIRDLNDLVMKNALQRVKSGFRSEKMTMTPH
Sbjct: 301 SERQMVLLHRIAKSGIRDLNDLVMKNALQRVKSGFRSEKMTMTPH 345
>gi|239757533 PREDICTED: ankyrin repeat domain 60 [Homo sapiens]
Length = 337
Score = 681 bits (1756), Expect = 0.0
Identities = 336/337 (99%), Positives = 336/337 (99%)
Query: 9 MRRAAAGAGGARAAGPTGGASRLHPNAGRRSGARAGAQGCGGPRVGSADSRALPAQPLAC 68
MRRAAAGAGGARAAGPTGGASRLHPNAGRRSGARAGAQGCGGPRVGSADSRALPAQPLAC
Sbjct: 1 MRRAAAGAGGARAAGPTGGASRLHPNAGRRSGARAGAQGCGGPRVGSADSRALPAQPLAC 60
Query: 69 ARGRSQRLVCDPKAASALPDLAPDVFVLRVRLEETGEMFRVANCRGDMTVRELKEELDLM 128
ARGRSQRLVCDPKAASALPDLAPDVFVLRVRLEETGEMFRVANCRGDMTVRELKEELDLM
Sbjct: 61 ARGRSQRLVCDPKAASALPDLAPDVFVLRVRLEETGEMFRVANCRGDMTVRELKEELDLM 120
Query: 129 VGIPFNLQRLQYLDEGVLMDDTTLKFHDVVPGGIISLCIWHHDGWTELVLAAVEGDPSKL 188
VGIPFNLQRLQYLDEGVLMDDTTLKFHDVVPGGIISLCIWHHDGWTELVLAAVEGDPSKL
Sbjct: 121 VGIPFNLQRLQYLDEGVLMDDTTLKFHDVVPGGIISLCIWHHDGWTELVLAAVEGDPSKL 180
Query: 189 SCLGLTEDSFYRTANSEHFEGEKWKHWTSQRAFVALYVASHRGHFDAVQYLLEHGASCLS 248
SCLGLTEDSFYRTANSEHFEGEKWKHWTSQRAFVALYVASHRGHFDAVQYLLEHGASCLS
Sbjct: 181 SCLGLTEDSFYRTANSEHFEGEKWKHWTSQRAFVALYVASHRGHFDAVQYLLEHGASCLS 240
Query: 249 RSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRDAKGETPISIAHRLNHTLSERQMVLL 308
RSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRDAKGETPISIAH LNHTLSERQMVLL
Sbjct: 241 RSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRDAKGETPISIAHCLNHTLSERQMVLL 300
Query: 309 HRIAKSGIRDLNDLVMKNALQRVKSGFRSEKMTMTPH 345
HRIAKSGIRDLNDLVMKNALQRVKSGFRSEKMTMTPH
Sbjct: 301 HRIAKSGIRDLNDLVMKNALQRVKSGFRSEKMTMTPH 337
>gi|239752049 PREDICTED: ankyrin repeat domain 60 [Homo sapiens]
Length = 337
Score = 681 bits (1756), Expect = 0.0
Identities = 336/337 (99%), Positives = 336/337 (99%)
Query: 9 MRRAAAGAGGARAAGPTGGASRLHPNAGRRSGARAGAQGCGGPRVGSADSRALPAQPLAC 68
MRRAAAGAGGARAAGPTGGASRLHPNAGRRSGARAGAQGCGGPRVGSADSRALPAQPLAC
Sbjct: 1 MRRAAAGAGGARAAGPTGGASRLHPNAGRRSGARAGAQGCGGPRVGSADSRALPAQPLAC 60
Query: 69 ARGRSQRLVCDPKAASALPDLAPDVFVLRVRLEETGEMFRVANCRGDMTVRELKEELDLM 128
ARGRSQRLVCDPKAASALPDLAPDVFVLRVRLEETGEMFRVANCRGDMTVRELKEELDLM
Sbjct: 61 ARGRSQRLVCDPKAASALPDLAPDVFVLRVRLEETGEMFRVANCRGDMTVRELKEELDLM 120
Query: 129 VGIPFNLQRLQYLDEGVLMDDTTLKFHDVVPGGIISLCIWHHDGWTELVLAAVEGDPSKL 188
VGIPFNLQRLQYLDEGVLMDDTTLKFHDVVPGGIISLCIWHHDGWTELVLAAVEGDPSKL
Sbjct: 121 VGIPFNLQRLQYLDEGVLMDDTTLKFHDVVPGGIISLCIWHHDGWTELVLAAVEGDPSKL 180
Query: 189 SCLGLTEDSFYRTANSEHFEGEKWKHWTSQRAFVALYVASHRGHFDAVQYLLEHGASCLS 248
SCLGLTEDSFYRTANSEHFEGEKWKHWTSQRAFVALYVASHRGHFDAVQYLLEHGASCLS
Sbjct: 181 SCLGLTEDSFYRTANSEHFEGEKWKHWTSQRAFVALYVASHRGHFDAVQYLLEHGASCLS 240
Query: 249 RSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRDAKGETPISIAHRLNHTLSERQMVLL 308
RSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRDAKGETPISIAH LNHTLSERQMVLL
Sbjct: 241 RSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRDAKGETPISIAHCLNHTLSERQMVLL 300
Query: 309 HRIAKSGIRDLNDLVMKNALQRVKSGFRSEKMTMTPH 345
HRIAKSGIRDLNDLVMKNALQRVKSGFRSEKMTMTPH
Sbjct: 301 HRIAKSGIRDLNDLVMKNALQRVKSGFRSEKMTMTPH 337
>gi|215598574 ankyrin 1 isoform 9 [Homo sapiens]
Length = 1897
Score = 71.6 bits (174), Expect = 9e-13
Identities = 34/83 (40%), Positives = 56/83 (67%)
Query: 216 TSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQH 275
T++ + L+VASH G+ V++LL+H A +++ LG +PLH AA G +D + LLL++
Sbjct: 730 TTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKN 789
Query: 276 GASIHDRDAKGETPISIAHRLNH 298
GAS ++ + G TP++IA RL +
Sbjct: 790 GASPNEVSSDGTTPLAIAKRLGY 812
Score = 58.9 bits (141), Expect = 6e-09
Identities = 39/111 (35%), Positives = 57/111 (51%), Gaps = 2/111 (1%)
Query: 221 FVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIH 280
F L++A + H ++ LL+ GAS + + G TPLHVA+ MG + LLQ GAS +
Sbjct: 405 FTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPN 464
Query: 281 DRDAKGETPISIAHRLNHTLSERQMVLLHRIAKSGIRDLNDLVMKNALQRV 331
+ K ETP+ +A R HT E LL AK + +D + R+
Sbjct: 465 VSNVKVETPLHMAARAGHT--EVAKYLLQNKAKVNAKAKDDQTPLHCAARI 513
Score = 57.4 bits (137), Expect = 2e-08
Identities = 35/97 (36%), Positives = 51/97 (52%), Gaps = 2/97 (2%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L+ A+ GH + LL+HGA +++ G +P+H+AA DC+ LLLQ+ A I D
Sbjct: 309 LHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDIT 368
Query: 284 AKGETPISIAHRLNHTLSERQMVLLHRIAKSGIRDLN 320
TP+ +A H + VLL + AK R LN
Sbjct: 369 LDHLTPLHVAAHCGHHRVAK--VLLDKGAKPNSRALN 403
Score = 53.5 bits (127), Expect = 3e-07
Identities = 30/89 (33%), Positives = 52/89 (58%), Gaps = 2/89 (2%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L++A+ GH + +YLL++ A +++ +TPLH AA +G ++ + LLL++ A+ +
Sbjct: 474 LHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLAT 533
Query: 284 AKGETPISIAHRLNHTLSERQMVLLHRIA 312
G TP+ IA R H E + LL + A
Sbjct: 534 TAGHTPLHIAAREGHV--ETVLALLEKEA 560
Score = 53.1 bits (126), Expect = 3e-07
Identities = 29/83 (34%), Positives = 45/83 (54%)
Query: 217 SQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHG 276
++ L+VAS GH V+ LL+ GAS + TPLH+AA G ++ LLQ+
Sbjct: 434 TESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNK 493
Query: 277 ASIHDRDAKGETPISIAHRLNHT 299
A ++ + +TP+ A R+ HT
Sbjct: 494 AKVNAKAKDDQTPLHCAARIGHT 516
Score = 52.8 bits (125), Expect = 5e-07
Identities = 30/85 (35%), Positives = 46/85 (54%)
Query: 214 HWTSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLL 273
++T Q L++AS RG+ V+ LL+ GA +++ TPLH AA G +LL
Sbjct: 266 NFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILL 325
Query: 274 QHGASIHDRDAKGETPISIAHRLNH 298
HGA I + G +PI +A + +H
Sbjct: 326 DHGAPIQAKTKNGLSPIHMAAQGDH 350
Score = 52.0 bits (123), Expect = 8e-07
Identities = 30/75 (40%), Positives = 41/75 (54%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L+VA+H GH + LL+ GA SR+ G TPLH+A + LLL+ GASI
Sbjct: 375 LHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVT 434
Query: 284 AKGETPISIAHRLNH 298
G TP+ +A + H
Sbjct: 435 ESGLTPLHVASFMGH 449
Score = 52.0 bits (123), Expect = 8e-07
Identities = 36/103 (34%), Positives = 54/103 (52%), Gaps = 8/103 (7%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L+VA H + D V+ LL G S S + G TPLH+AA + + LLQ+G S +
Sbjct: 606 LHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAES 665
Query: 284 AKGETPISIAHRLNHTLSERQMVLLHRIA------KSGIRDLN 320
+G TP+ +A + H +E +LL + A KSG+ L+
Sbjct: 666 VQGVTPLHLAAQEGH--AEMVALLLSKQANGNLGNKSGLTPLH 706
Score = 50.4 bits (119), Expect = 2e-06
Identities = 29/82 (35%), Positives = 40/82 (48%)
Query: 217 SQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHG 276
S+ F L++A+H + + Q LL GAS G TPLH+A+ G + LLL G
Sbjct: 236 SKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRG 295
Query: 277 ASIHDRDAKGETPISIAHRLNH 298
A I + TP+ A R H
Sbjct: 296 AQIETKTKDELTPLHCAARNGH 317
Score = 50.1 bits (118), Expect = 3e-06
Identities = 24/76 (31%), Positives = 40/76 (52%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L++ + GH L++HG + + +G TPLHVA+ G + LLQH A ++ +
Sbjct: 705 LHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKT 764
Query: 284 AKGETPISIAHRLNHT 299
G +P+ A + HT
Sbjct: 765 KLGYSPLHQAAQQGHT 780
Score = 49.7 bits (117), Expect = 4e-06
Identities = 38/114 (33%), Positives = 57/114 (50%), Gaps = 6/114 (5%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L+ A+ GH + V+ LLE+ A+ + G TPLH+AA G + ++ LL+ AS
Sbjct: 507 LHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMT 566
Query: 284 AKGETPISIAH-----RLNHTLSERQMVLLHRIAKSGIRDLNDLVMKNALQRVK 332
KG TP+ +A R+ L ER + K+G+ L+ V N L VK
Sbjct: 567 KKGFTPLHVAAKYGKVRVAELLLERD-AHPNAAGKNGLTPLHVAVHHNNLDIVK 619
Score = 49.3 bits (116), Expect = 5e-06
Identities = 32/109 (29%), Positives = 52/109 (47%), Gaps = 7/109 (6%)
Query: 197 SFYRTANS-------EHFEGEKWKHWTSQRAFVALYVASHRGHFDAVQYLLEHGASCLSR 249
SF R A S +H + +Q L++AS GH V LL +
Sbjct: 48 SFLRAARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETT 107
Query: 250 SPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRDAKGETPISIAHRLNH 298
+ G T LH+AA G+ + + L+ +GA+++ + KG TP+ +A + NH
Sbjct: 108 TKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENH 156
Score = 48.9 bits (115), Expect = 7e-06
Identities = 43/135 (31%), Positives = 62/135 (45%), Gaps = 17/135 (12%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
+++A+ H D V+ LL++ A + TPLHVAA G +LL GA + R
Sbjct: 342 IHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRA 401
Query: 284 AKGETPISIAHRLNHTLSERQMVLLHR-------IAKSGIRDLNDL-------VMKNALQ 329
G TP+ IA + NH R M LL + + +SG+ L+ ++KN LQ
Sbjct: 402 LNGFTPLHIACKKNHV---RVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQ 458
Query: 330 RVKSGFRSEKMTMTP 344
R S S TP
Sbjct: 459 RGASPNVSNVKVETP 473
Score = 48.5 bits (114), Expect = 9e-06
Identities = 30/90 (33%), Positives = 42/90 (46%)
Query: 217 SQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHG 276
+++ F L+VA+ G + LLE A + G TPLHVA D + LLL G
Sbjct: 566 TKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRG 625
Query: 277 ASIHDRDAKGETPISIAHRLNHTLSERQMV 306
S H G TP+ IA + N R ++
Sbjct: 626 GSPHSPAWNGYTPLHIAAKQNQVEVARSLL 655
Score = 48.1 bits (113), Expect = 1e-05
Identities = 25/83 (30%), Positives = 50/83 (60%)
Query: 216 TSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQH 275
T+++ AL++A+ G + V+ L+ +GA+ ++S G TPL++AA + + LL++
Sbjct: 107 TTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLEN 166
Query: 276 GASIHDRDAKGETPISIAHRLNH 298
GA+ + G TP+++A + H
Sbjct: 167 GANQNVATEDGFTPLAVALQQGH 189
Score = 46.6 bits (109), Expect = 3e-05
Identities = 24/85 (28%), Positives = 45/85 (52%)
Query: 214 HWTSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLL 273
H + + L++A+ + + + LL++G S + S G TPLH+AA G ++ + LLL
Sbjct: 629 HSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLL 688
Query: 274 QHGASIHDRDAKGETPISIAHRLNH 298
A+ + + G TP+ + + H
Sbjct: 689 SKQANGNLGNKSGLTPLHLVAQEGH 713
Score = 45.1 bits (105), Expect = 1e-04
Identities = 22/60 (36%), Positives = 35/60 (58%)
Query: 217 SQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHG 276
SQ+ F LY+A+ H + V++LLE+GA+ + G TPL VA G + + L+ +G
Sbjct: 141 SQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYG 200
Score = 44.7 bits (104), Expect = 1e-04
Identities = 34/125 (27%), Positives = 56/125 (44%), Gaps = 15/125 (12%)
Query: 217 SQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHG 276
S + L++A+ GH + V LL A+ + G TPLH+ A G +L++HG
Sbjct: 665 SVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHG 724
Query: 277 ASIHDRDAKGETPISIAH-----RLNHTLSERQMVL----------LHRIAKSGIRDLND 321
+ G TP+ +A +L L + Q + LH+ A+ G D+
Sbjct: 725 VMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVT 784
Query: 322 LVMKN 326
L++KN
Sbjct: 785 LLLKN 789
Score = 42.0 bits (97), Expect = 8e-04
Identities = 41/160 (25%), Positives = 63/160 (39%), Gaps = 38/160 (23%)
Query: 199 YRTANSEHFEGEKW-------KHWTSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSP 251
Y A H E K+ ++ ++ F L VA +GH + V +L+ +G R P
Sbjct: 149 YMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLP 208
Query: 252 L-----------------------------GRTPLHVAAAMGRSDCIILLLQHGASIHDR 282
G TPLH+AA + LLL GAS++
Sbjct: 209 ALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFT 268
Query: 283 DAKGETPISIAHRLNHTLSERQMVLLHRIAKSGIRDLNDL 322
G TP+ IA R + + R +LL R A+ + ++L
Sbjct: 269 PQNGITPLHIASRRGNVIMVR--LLLDRGAQIETKTKDEL 306
>gi|70780359 ankyrin 1 isoform 1 [Homo sapiens]
Length = 1881
Score = 71.6 bits (174), Expect = 9e-13
Identities = 34/83 (40%), Positives = 56/83 (67%)
Query: 216 TSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQH 275
T++ + L+VASH G+ V++LL+H A +++ LG +PLH AA G +D + LLL++
Sbjct: 697 TTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKN 756
Query: 276 GASIHDRDAKGETPISIAHRLNH 298
GAS ++ + G TP++IA RL +
Sbjct: 757 GASPNEVSSDGTTPLAIAKRLGY 779
Score = 58.9 bits (141), Expect = 6e-09
Identities = 39/111 (35%), Positives = 57/111 (51%), Gaps = 2/111 (1%)
Query: 221 FVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIH 280
F L++A + H ++ LL+ GAS + + G TPLHVA+ MG + LLQ GAS +
Sbjct: 372 FTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPN 431
Query: 281 DRDAKGETPISIAHRLNHTLSERQMVLLHRIAKSGIRDLNDLVMKNALQRV 331
+ K ETP+ +A R HT E LL AK + +D + R+
Sbjct: 432 VSNVKVETPLHMAARAGHT--EVAKYLLQNKAKVNAKAKDDQTPLHCAARI 480
Score = 57.4 bits (137), Expect = 2e-08
Identities = 35/97 (36%), Positives = 51/97 (52%), Gaps = 2/97 (2%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L+ A+ GH + LL+HGA +++ G +P+H+AA DC+ LLLQ+ A I D
Sbjct: 276 LHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDIT 335
Query: 284 AKGETPISIAHRLNHTLSERQMVLLHRIAKSGIRDLN 320
TP+ +A H + VLL + AK R LN
Sbjct: 336 LDHLTPLHVAAHCGHHRVAK--VLLDKGAKPNSRALN 370
Score = 53.5 bits (127), Expect = 3e-07
Identities = 30/89 (33%), Positives = 52/89 (58%), Gaps = 2/89 (2%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L++A+ GH + +YLL++ A +++ +TPLH AA +G ++ + LLL++ A+ +
Sbjct: 441 LHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLAT 500
Query: 284 AKGETPISIAHRLNHTLSERQMVLLHRIA 312
G TP+ IA R H E + LL + A
Sbjct: 501 TAGHTPLHIAAREGHV--ETVLALLEKEA 527
Score = 53.1 bits (126), Expect = 3e-07
Identities = 29/83 (34%), Positives = 45/83 (54%)
Query: 217 SQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHG 276
++ L+VAS GH V+ LL+ GAS + TPLH+AA G ++ LLQ+
Sbjct: 401 TESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNK 460
Query: 277 ASIHDRDAKGETPISIAHRLNHT 299
A ++ + +TP+ A R+ HT
Sbjct: 461 AKVNAKAKDDQTPLHCAARIGHT 483
Score = 52.8 bits (125), Expect = 5e-07
Identities = 30/85 (35%), Positives = 46/85 (54%)
Query: 214 HWTSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLL 273
++T Q L++AS RG+ V+ LL+ GA +++ TPLH AA G +LL
Sbjct: 233 NFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILL 292
Query: 274 QHGASIHDRDAKGETPISIAHRLNH 298
HGA I + G +PI +A + +H
Sbjct: 293 DHGAPIQAKTKNGLSPIHMAAQGDH 317
Score = 52.0 bits (123), Expect = 8e-07
Identities = 30/75 (40%), Positives = 41/75 (54%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L+VA+H GH + LL+ GA SR+ G TPLH+A + LLL+ GASI
Sbjct: 342 LHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVT 401
Query: 284 AKGETPISIAHRLNH 298
G TP+ +A + H
Sbjct: 402 ESGLTPLHVASFMGH 416
Score = 52.0 bits (123), Expect = 8e-07
Identities = 36/103 (34%), Positives = 54/103 (52%), Gaps = 8/103 (7%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L+VA H + D V+ LL G S S + G TPLH+AA + + LLQ+G S +
Sbjct: 573 LHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAES 632
Query: 284 AKGETPISIAHRLNHTLSERQMVLLHRIA------KSGIRDLN 320
+G TP+ +A + H +E +LL + A KSG+ L+
Sbjct: 633 VQGVTPLHLAAQEGH--AEMVALLLSKQANGNLGNKSGLTPLH 673
Score = 50.4 bits (119), Expect = 2e-06
Identities = 29/82 (35%), Positives = 40/82 (48%)
Query: 217 SQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHG 276
S+ F L++A+H + + Q LL GAS G TPLH+A+ G + LLL G
Sbjct: 203 SKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRG 262
Query: 277 ASIHDRDAKGETPISIAHRLNH 298
A I + TP+ A R H
Sbjct: 263 AQIETKTKDELTPLHCAARNGH 284
Score = 50.1 bits (118), Expect = 3e-06
Identities = 24/76 (31%), Positives = 40/76 (52%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L++ + GH L++HG + + +G TPLHVA+ G + LLQH A ++ +
Sbjct: 672 LHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKT 731
Query: 284 AKGETPISIAHRLNHT 299
G +P+ A + HT
Sbjct: 732 KLGYSPLHQAAQQGHT 747
Score = 49.7 bits (117), Expect = 4e-06
Identities = 38/114 (33%), Positives = 57/114 (50%), Gaps = 6/114 (5%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L+ A+ GH + V+ LLE+ A+ + G TPLH+AA G + ++ LL+ AS
Sbjct: 474 LHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMT 533
Query: 284 AKGETPISIAH-----RLNHTLSERQMVLLHRIAKSGIRDLNDLVMKNALQRVK 332
KG TP+ +A R+ L ER + K+G+ L+ V N L VK
Sbjct: 534 KKGFTPLHVAAKYGKVRVAELLLERD-AHPNAAGKNGLTPLHVAVHHNNLDIVK 586
Score = 49.3 bits (116), Expect = 5e-06
Identities = 32/109 (29%), Positives = 52/109 (47%), Gaps = 7/109 (6%)
Query: 197 SFYRTANS-------EHFEGEKWKHWTSQRAFVALYVASHRGHFDAVQYLLEHGASCLSR 249
SF R A S +H + +Q L++AS GH V LL +
Sbjct: 15 SFLRAARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETT 74
Query: 250 SPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRDAKGETPISIAHRLNH 298
+ G T LH+AA G+ + + L+ +GA+++ + KG TP+ +A + NH
Sbjct: 75 TKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENH 123
Score = 48.9 bits (115), Expect = 7e-06
Identities = 43/135 (31%), Positives = 62/135 (45%), Gaps = 17/135 (12%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
+++A+ H D V+ LL++ A + TPLHVAA G +LL GA + R
Sbjct: 309 IHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRA 368
Query: 284 AKGETPISIAHRLNHTLSERQMVLLHR-------IAKSGIRDLNDL-------VMKNALQ 329
G TP+ IA + NH R M LL + + +SG+ L+ ++KN LQ
Sbjct: 369 LNGFTPLHIACKKNHV---RVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQ 425
Query: 330 RVKSGFRSEKMTMTP 344
R S S TP
Sbjct: 426 RGASPNVSNVKVETP 440
Score = 48.5 bits (114), Expect = 9e-06
Identities = 30/90 (33%), Positives = 42/90 (46%)
Query: 217 SQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHG 276
+++ F L+VA+ G + LLE A + G TPLHVA D + LLL G
Sbjct: 533 TKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRG 592
Query: 277 ASIHDRDAKGETPISIAHRLNHTLSERQMV 306
S H G TP+ IA + N R ++
Sbjct: 593 GSPHSPAWNGYTPLHIAAKQNQVEVARSLL 622
Score = 48.1 bits (113), Expect = 1e-05
Identities = 25/83 (30%), Positives = 50/83 (60%)
Query: 216 TSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQH 275
T+++ AL++A+ G + V+ L+ +GA+ ++S G TPL++AA + + LL++
Sbjct: 74 TTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLEN 133
Query: 276 GASIHDRDAKGETPISIAHRLNH 298
GA+ + G TP+++A + H
Sbjct: 134 GANQNVATEDGFTPLAVALQQGH 156
Score = 46.6 bits (109), Expect = 3e-05
Identities = 24/85 (28%), Positives = 45/85 (52%)
Query: 214 HWTSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLL 273
H + + L++A+ + + + LL++G S + S G TPLH+AA G ++ + LLL
Sbjct: 596 HSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLL 655
Query: 274 QHGASIHDRDAKGETPISIAHRLNH 298
A+ + + G TP+ + + H
Sbjct: 656 SKQANGNLGNKSGLTPLHLVAQEGH 680
Score = 45.1 bits (105), Expect = 1e-04
Identities = 22/60 (36%), Positives = 35/60 (58%)
Query: 217 SQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHG 276
SQ+ F LY+A+ H + V++LLE+GA+ + G TPL VA G + + L+ +G
Sbjct: 108 SQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYG 167
Score = 44.7 bits (104), Expect = 1e-04
Identities = 34/125 (27%), Positives = 56/125 (44%), Gaps = 15/125 (12%)
Query: 217 SQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHG 276
S + L++A+ GH + V LL A+ + G TPLH+ A G +L++HG
Sbjct: 632 SVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHG 691
Query: 277 ASIHDRDAKGETPISIAH-----RLNHTLSERQMVL----------LHRIAKSGIRDLND 321
+ G TP+ +A +L L + Q + LH+ A+ G D+
Sbjct: 692 VMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVT 751
Query: 322 LVMKN 326
L++KN
Sbjct: 752 LLLKN 756
Score = 42.0 bits (97), Expect = 8e-04
Identities = 41/160 (25%), Positives = 63/160 (39%), Gaps = 38/160 (23%)
Query: 199 YRTANSEHFEGEKW-------KHWTSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSP 251
Y A H E K+ ++ ++ F L VA +GH + V +L+ +G R P
Sbjct: 116 YMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLP 175
Query: 252 L-----------------------------GRTPLHVAAAMGRSDCIILLLQHGASIHDR 282
G TPLH+AA + LLL GAS++
Sbjct: 176 ALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFT 235
Query: 283 DAKGETPISIAHRLNHTLSERQMVLLHRIAKSGIRDLNDL 322
G TP+ IA R + + R +LL R A+ + ++L
Sbjct: 236 PQNGITPLHIASRRGNVIMVR--LLLDRGAQIETKTKDEL 273
>gi|70780357 ankyrin 1 isoform 3 [Homo sapiens]
Length = 1880
Score = 71.6 bits (174), Expect = 9e-13
Identities = 34/83 (40%), Positives = 56/83 (67%)
Query: 216 TSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQH 275
T++ + L+VASH G+ V++LL+H A +++ LG +PLH AA G +D + LLL++
Sbjct: 697 TTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKN 756
Query: 276 GASIHDRDAKGETPISIAHRLNH 298
GAS ++ + G TP++IA RL +
Sbjct: 757 GASPNEVSSDGTTPLAIAKRLGY 779
Score = 58.9 bits (141), Expect = 6e-09
Identities = 39/111 (35%), Positives = 57/111 (51%), Gaps = 2/111 (1%)
Query: 221 FVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIH 280
F L++A + H ++ LL+ GAS + + G TPLHVA+ MG + LLQ GAS +
Sbjct: 372 FTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPN 431
Query: 281 DRDAKGETPISIAHRLNHTLSERQMVLLHRIAKSGIRDLNDLVMKNALQRV 331
+ K ETP+ +A R HT E LL AK + +D + R+
Sbjct: 432 VSNVKVETPLHMAARAGHT--EVAKYLLQNKAKVNAKAKDDQTPLHCAARI 480
Score = 57.4 bits (137), Expect = 2e-08
Identities = 35/97 (36%), Positives = 51/97 (52%), Gaps = 2/97 (2%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L+ A+ GH + LL+HGA +++ G +P+H+AA DC+ LLLQ+ A I D
Sbjct: 276 LHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDIT 335
Query: 284 AKGETPISIAHRLNHTLSERQMVLLHRIAKSGIRDLN 320
TP+ +A H + VLL + AK R LN
Sbjct: 336 LDHLTPLHVAAHCGHHRVAK--VLLDKGAKPNSRALN 370
Score = 53.5 bits (127), Expect = 3e-07
Identities = 30/89 (33%), Positives = 52/89 (58%), Gaps = 2/89 (2%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L++A+ GH + +YLL++ A +++ +TPLH AA +G ++ + LLL++ A+ +
Sbjct: 441 LHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLAT 500
Query: 284 AKGETPISIAHRLNHTLSERQMVLLHRIA 312
G TP+ IA R H E + LL + A
Sbjct: 501 TAGHTPLHIAAREGHV--ETVLALLEKEA 527
Score = 53.1 bits (126), Expect = 3e-07
Identities = 29/83 (34%), Positives = 45/83 (54%)
Query: 217 SQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHG 276
++ L+VAS GH V+ LL+ GAS + TPLH+AA G ++ LLQ+
Sbjct: 401 TESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNK 460
Query: 277 ASIHDRDAKGETPISIAHRLNHT 299
A ++ + +TP+ A R+ HT
Sbjct: 461 AKVNAKAKDDQTPLHCAARIGHT 483
Score = 52.8 bits (125), Expect = 5e-07
Identities = 30/85 (35%), Positives = 46/85 (54%)
Query: 214 HWTSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLL 273
++T Q L++AS RG+ V+ LL+ GA +++ TPLH AA G +LL
Sbjct: 233 NFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILL 292
Query: 274 QHGASIHDRDAKGETPISIAHRLNH 298
HGA I + G +PI +A + +H
Sbjct: 293 DHGAPIQAKTKNGLSPIHMAAQGDH 317
Score = 52.0 bits (123), Expect = 8e-07
Identities = 30/75 (40%), Positives = 41/75 (54%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L+VA+H GH + LL+ GA SR+ G TPLH+A + LLL+ GASI
Sbjct: 342 LHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVT 401
Query: 284 AKGETPISIAHRLNH 298
G TP+ +A + H
Sbjct: 402 ESGLTPLHVASFMGH 416
Score = 52.0 bits (123), Expect = 8e-07
Identities = 36/103 (34%), Positives = 54/103 (52%), Gaps = 8/103 (7%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L+VA H + D V+ LL G S S + G TPLH+AA + + LLQ+G S +
Sbjct: 573 LHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAES 632
Query: 284 AKGETPISIAHRLNHTLSERQMVLLHRIA------KSGIRDLN 320
+G TP+ +A + H +E +LL + A KSG+ L+
Sbjct: 633 VQGVTPLHLAAQEGH--AEMVALLLSKQANGNLGNKSGLTPLH 673
Score = 50.4 bits (119), Expect = 2e-06
Identities = 29/82 (35%), Positives = 40/82 (48%)
Query: 217 SQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHG 276
S+ F L++A+H + + Q LL GAS G TPLH+A+ G + LLL G
Sbjct: 203 SKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRG 262
Query: 277 ASIHDRDAKGETPISIAHRLNH 298
A I + TP+ A R H
Sbjct: 263 AQIETKTKDELTPLHCAARNGH 284
Score = 50.1 bits (118), Expect = 3e-06
Identities = 24/76 (31%), Positives = 40/76 (52%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L++ + GH L++HG + + +G TPLHVA+ G + LLQH A ++ +
Sbjct: 672 LHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKT 731
Query: 284 AKGETPISIAHRLNHT 299
G +P+ A + HT
Sbjct: 732 KLGYSPLHQAAQQGHT 747
Score = 49.7 bits (117), Expect = 4e-06
Identities = 38/114 (33%), Positives = 57/114 (50%), Gaps = 6/114 (5%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L+ A+ GH + V+ LLE+ A+ + G TPLH+AA G + ++ LL+ AS
Sbjct: 474 LHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMT 533
Query: 284 AKGETPISIAH-----RLNHTLSERQMVLLHRIAKSGIRDLNDLVMKNALQRVK 332
KG TP+ +A R+ L ER + K+G+ L+ V N L VK
Sbjct: 534 KKGFTPLHVAAKYGKVRVAELLLERD-AHPNAAGKNGLTPLHVAVHHNNLDIVK 586
Score = 49.3 bits (116), Expect = 5e-06
Identities = 32/109 (29%), Positives = 52/109 (47%), Gaps = 7/109 (6%)
Query: 197 SFYRTANS-------EHFEGEKWKHWTSQRAFVALYVASHRGHFDAVQYLLEHGASCLSR 249
SF R A S +H + +Q L++AS GH V LL +
Sbjct: 15 SFLRAARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETT 74
Query: 250 SPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRDAKGETPISIAHRLNH 298
+ G T LH+AA G+ + + L+ +GA+++ + KG TP+ +A + NH
Sbjct: 75 TKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENH 123
Score = 48.9 bits (115), Expect = 7e-06
Identities = 43/135 (31%), Positives = 62/135 (45%), Gaps = 17/135 (12%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
+++A+ H D V+ LL++ A + TPLHVAA G +LL GA + R
Sbjct: 309 IHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRA 368
Query: 284 AKGETPISIAHRLNHTLSERQMVLLHR-------IAKSGIRDLNDL-------VMKNALQ 329
G TP+ IA + NH R M LL + + +SG+ L+ ++KN LQ
Sbjct: 369 LNGFTPLHIACKKNHV---RVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQ 425
Query: 330 RVKSGFRSEKMTMTP 344
R S S TP
Sbjct: 426 RGASPNVSNVKVETP 440
Score = 48.5 bits (114), Expect = 9e-06
Identities = 30/90 (33%), Positives = 42/90 (46%)
Query: 217 SQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHG 276
+++ F L+VA+ G + LLE A + G TPLHVA D + LLL G
Sbjct: 533 TKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRG 592
Query: 277 ASIHDRDAKGETPISIAHRLNHTLSERQMV 306
S H G TP+ IA + N R ++
Sbjct: 593 GSPHSPAWNGYTPLHIAAKQNQVEVARSLL 622
Score = 48.1 bits (113), Expect = 1e-05
Identities = 25/83 (30%), Positives = 50/83 (60%)
Query: 216 TSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQH 275
T+++ AL++A+ G + V+ L+ +GA+ ++S G TPL++AA + + LL++
Sbjct: 74 TTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLEN 133
Query: 276 GASIHDRDAKGETPISIAHRLNH 298
GA+ + G TP+++A + H
Sbjct: 134 GANQNVATEDGFTPLAVALQQGH 156
Score = 46.6 bits (109), Expect = 3e-05
Identities = 24/85 (28%), Positives = 45/85 (52%)
Query: 214 HWTSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLL 273
H + + L++A+ + + + LL++G S + S G TPLH+AA G ++ + LLL
Sbjct: 596 HSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLL 655
Query: 274 QHGASIHDRDAKGETPISIAHRLNH 298
A+ + + G TP+ + + H
Sbjct: 656 SKQANGNLGNKSGLTPLHLVAQEGH 680
Score = 45.1 bits (105), Expect = 1e-04
Identities = 22/60 (36%), Positives = 35/60 (58%)
Query: 217 SQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHG 276
SQ+ F LY+A+ H + V++LLE+GA+ + G TPL VA G + + L+ +G
Sbjct: 108 SQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYG 167
Score = 44.7 bits (104), Expect = 1e-04
Identities = 34/125 (27%), Positives = 56/125 (44%), Gaps = 15/125 (12%)
Query: 217 SQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHG 276
S + L++A+ GH + V LL A+ + G TPLH+ A G +L++HG
Sbjct: 632 SVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHG 691
Query: 277 ASIHDRDAKGETPISIAH-----RLNHTLSERQMVL----------LHRIAKSGIRDLND 321
+ G TP+ +A +L L + Q + LH+ A+ G D+
Sbjct: 692 VMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVT 751
Query: 322 LVMKN 326
L++KN
Sbjct: 752 LLLKN 756
Score = 42.0 bits (97), Expect = 8e-04
Identities = 41/160 (25%), Positives = 63/160 (39%), Gaps = 38/160 (23%)
Query: 199 YRTANSEHFEGEKW-------KHWTSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSP 251
Y A H E K+ ++ ++ F L VA +GH + V +L+ +G R P
Sbjct: 116 YMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLP 175
Query: 252 L-----------------------------GRTPLHVAAAMGRSDCIILLLQHGASIHDR 282
G TPLH+AA + LLL GAS++
Sbjct: 176 ALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFT 235
Query: 283 DAKGETPISIAHRLNHTLSERQMVLLHRIAKSGIRDLNDL 322
G TP+ IA R + + R +LL R A+ + ++L
Sbjct: 236 PQNGITPLHIASRRGNVIMVR--LLLDRGAQIETKTKDEL 273
>gi|70780355 ankyrin 1 isoform 2 [Homo sapiens]
Length = 1719
Score = 71.6 bits (174), Expect = 9e-13
Identities = 34/83 (40%), Positives = 56/83 (67%)
Query: 216 TSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQH 275
T++ + L+VASH G+ V++LL+H A +++ LG +PLH AA G +D + LLL++
Sbjct: 697 TTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKN 756
Query: 276 GASIHDRDAKGETPISIAHRLNH 298
GAS ++ + G TP++IA RL +
Sbjct: 757 GASPNEVSSDGTTPLAIAKRLGY 779
Score = 58.9 bits (141), Expect = 6e-09
Identities = 39/111 (35%), Positives = 57/111 (51%), Gaps = 2/111 (1%)
Query: 221 FVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIH 280
F L++A + H ++ LL+ GAS + + G TPLHVA+ MG + LLQ GAS +
Sbjct: 372 FTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPN 431
Query: 281 DRDAKGETPISIAHRLNHTLSERQMVLLHRIAKSGIRDLNDLVMKNALQRV 331
+ K ETP+ +A R HT E LL AK + +D + R+
Sbjct: 432 VSNVKVETPLHMAARAGHT--EVAKYLLQNKAKVNAKAKDDQTPLHCAARI 480
Score = 57.4 bits (137), Expect = 2e-08
Identities = 35/97 (36%), Positives = 51/97 (52%), Gaps = 2/97 (2%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L+ A+ GH + LL+HGA +++ G +P+H+AA DC+ LLLQ+ A I D
Sbjct: 276 LHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDIT 335
Query: 284 AKGETPISIAHRLNHTLSERQMVLLHRIAKSGIRDLN 320
TP+ +A H + VLL + AK R LN
Sbjct: 336 LDHLTPLHVAAHCGHHRVAK--VLLDKGAKPNSRALN 370
Score = 53.5 bits (127), Expect = 3e-07
Identities = 30/89 (33%), Positives = 52/89 (58%), Gaps = 2/89 (2%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L++A+ GH + +YLL++ A +++ +TPLH AA +G ++ + LLL++ A+ +
Sbjct: 441 LHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLAT 500
Query: 284 AKGETPISIAHRLNHTLSERQMVLLHRIA 312
G TP+ IA R H E + LL + A
Sbjct: 501 TAGHTPLHIAAREGHV--ETVLALLEKEA 527
Score = 53.1 bits (126), Expect = 3e-07
Identities = 29/83 (34%), Positives = 45/83 (54%)
Query: 217 SQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHG 276
++ L+VAS GH V+ LL+ GAS + TPLH+AA G ++ LLQ+
Sbjct: 401 TESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNK 460
Query: 277 ASIHDRDAKGETPISIAHRLNHT 299
A ++ + +TP+ A R+ HT
Sbjct: 461 AKVNAKAKDDQTPLHCAARIGHT 483
Score = 52.8 bits (125), Expect = 5e-07
Identities = 30/85 (35%), Positives = 46/85 (54%)
Query: 214 HWTSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLL 273
++T Q L++AS RG+ V+ LL+ GA +++ TPLH AA G +LL
Sbjct: 233 NFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILL 292
Query: 274 QHGASIHDRDAKGETPISIAHRLNH 298
HGA I + G +PI +A + +H
Sbjct: 293 DHGAPIQAKTKNGLSPIHMAAQGDH 317
Score = 52.0 bits (123), Expect = 8e-07
Identities = 30/75 (40%), Positives = 41/75 (54%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L+VA+H GH + LL+ GA SR+ G TPLH+A + LLL+ GASI
Sbjct: 342 LHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVT 401
Query: 284 AKGETPISIAHRLNH 298
G TP+ +A + H
Sbjct: 402 ESGLTPLHVASFMGH 416
Score = 52.0 bits (123), Expect = 8e-07
Identities = 36/103 (34%), Positives = 54/103 (52%), Gaps = 8/103 (7%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L+VA H + D V+ LL G S S + G TPLH+AA + + LLQ+G S +
Sbjct: 573 LHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAES 632
Query: 284 AKGETPISIAHRLNHTLSERQMVLLHRIA------KSGIRDLN 320
+G TP+ +A + H +E +LL + A KSG+ L+
Sbjct: 633 VQGVTPLHLAAQEGH--AEMVALLLSKQANGNLGNKSGLTPLH 673
Score = 50.4 bits (119), Expect = 2e-06
Identities = 29/82 (35%), Positives = 40/82 (48%)
Query: 217 SQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHG 276
S+ F L++A+H + + Q LL GAS G TPLH+A+ G + LLL G
Sbjct: 203 SKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRG 262
Query: 277 ASIHDRDAKGETPISIAHRLNH 298
A I + TP+ A R H
Sbjct: 263 AQIETKTKDELTPLHCAARNGH 284
Score = 50.1 bits (118), Expect = 3e-06
Identities = 24/76 (31%), Positives = 40/76 (52%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L++ + GH L++HG + + +G TPLHVA+ G + LLQH A ++ +
Sbjct: 672 LHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKT 731
Query: 284 AKGETPISIAHRLNHT 299
G +P+ A + HT
Sbjct: 732 KLGYSPLHQAAQQGHT 747
Score = 49.7 bits (117), Expect = 4e-06
Identities = 38/114 (33%), Positives = 57/114 (50%), Gaps = 6/114 (5%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L+ A+ GH + V+ LLE+ A+ + G TPLH+AA G + ++ LL+ AS
Sbjct: 474 LHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMT 533
Query: 284 AKGETPISIAH-----RLNHTLSERQMVLLHRIAKSGIRDLNDLVMKNALQRVK 332
KG TP+ +A R+ L ER + K+G+ L+ V N L VK
Sbjct: 534 KKGFTPLHVAAKYGKVRVAELLLERD-AHPNAAGKNGLTPLHVAVHHNNLDIVK 586
Score = 49.3 bits (116), Expect = 5e-06
Identities = 32/109 (29%), Positives = 52/109 (47%), Gaps = 7/109 (6%)
Query: 197 SFYRTANS-------EHFEGEKWKHWTSQRAFVALYVASHRGHFDAVQYLLEHGASCLSR 249
SF R A S +H + +Q L++AS GH V LL +
Sbjct: 15 SFLRAARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETT 74
Query: 250 SPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRDAKGETPISIAHRLNH 298
+ G T LH+AA G+ + + L+ +GA+++ + KG TP+ +A + NH
Sbjct: 75 TKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENH 123
Score = 48.9 bits (115), Expect = 7e-06
Identities = 43/135 (31%), Positives = 62/135 (45%), Gaps = 17/135 (12%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
+++A+ H D V+ LL++ A + TPLHVAA G +LL GA + R
Sbjct: 309 IHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRA 368
Query: 284 AKGETPISIAHRLNHTLSERQMVLLHR-------IAKSGIRDLNDL-------VMKNALQ 329
G TP+ IA + NH R M LL + + +SG+ L+ ++KN LQ
Sbjct: 369 LNGFTPLHIACKKNHV---RVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQ 425
Query: 330 RVKSGFRSEKMTMTP 344
R S S TP
Sbjct: 426 RGASPNVSNVKVETP 440
Score = 48.5 bits (114), Expect = 9e-06
Identities = 30/90 (33%), Positives = 42/90 (46%)
Query: 217 SQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHG 276
+++ F L+VA+ G + LLE A + G TPLHVA D + LLL G
Sbjct: 533 TKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRG 592
Query: 277 ASIHDRDAKGETPISIAHRLNHTLSERQMV 306
S H G TP+ IA + N R ++
Sbjct: 593 GSPHSPAWNGYTPLHIAAKQNQVEVARSLL 622
Score = 48.1 bits (113), Expect = 1e-05
Identities = 25/83 (30%), Positives = 50/83 (60%)
Query: 216 TSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQH 275
T+++ AL++A+ G + V+ L+ +GA+ ++S G TPL++AA + + LL++
Sbjct: 74 TTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLEN 133
Query: 276 GASIHDRDAKGETPISIAHRLNH 298
GA+ + G TP+++A + H
Sbjct: 134 GANQNVATEDGFTPLAVALQQGH 156
Score = 46.6 bits (109), Expect = 3e-05
Identities = 24/85 (28%), Positives = 45/85 (52%)
Query: 214 HWTSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLL 273
H + + L++A+ + + + LL++G S + S G TPLH+AA G ++ + LLL
Sbjct: 596 HSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLL 655
Query: 274 QHGASIHDRDAKGETPISIAHRLNH 298
A+ + + G TP+ + + H
Sbjct: 656 SKQANGNLGNKSGLTPLHLVAQEGH 680
Score = 45.1 bits (105), Expect = 1e-04
Identities = 22/60 (36%), Positives = 35/60 (58%)
Query: 217 SQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHG 276
SQ+ F LY+A+ H + V++LLE+GA+ + G TPL VA G + + L+ +G
Sbjct: 108 SQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYG 167
Score = 44.7 bits (104), Expect = 1e-04
Identities = 34/125 (27%), Positives = 56/125 (44%), Gaps = 15/125 (12%)
Query: 217 SQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHG 276
S + L++A+ GH + V LL A+ + G TPLH+ A G +L++HG
Sbjct: 632 SVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHG 691
Query: 277 ASIHDRDAKGETPISIAH-----RLNHTLSERQMVL----------LHRIAKSGIRDLND 321
+ G TP+ +A +L L + Q + LH+ A+ G D+
Sbjct: 692 VMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVT 751
Query: 322 LVMKN 326
L++KN
Sbjct: 752 LLLKN 756
Score = 42.0 bits (97), Expect = 8e-04
Identities = 41/160 (25%), Positives = 63/160 (39%), Gaps = 38/160 (23%)
Query: 199 YRTANSEHFEGEKW-------KHWTSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSP 251
Y A H E K+ ++ ++ F L VA +GH + V +L+ +G R P
Sbjct: 116 YMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLP 175
Query: 252 L-----------------------------GRTPLHVAAAMGRSDCIILLLQHGASIHDR 282
G TPLH+AA + LLL GAS++
Sbjct: 176 ALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFT 235
Query: 283 DAKGETPISIAHRLNHTLSERQMVLLHRIAKSGIRDLNDL 322
G TP+ IA R + + R +LL R A+ + ++L
Sbjct: 236 PQNGITPLHIASRRGNVIMVR--LLLDRGAQIETKTKDEL 273
>gi|70780353 ankyrin 1 isoform 4 [Homo sapiens]
Length = 1856
Score = 71.6 bits (174), Expect = 9e-13
Identities = 34/83 (40%), Positives = 56/83 (67%)
Query: 216 TSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQH 275
T++ + L+VASH G+ V++LL+H A +++ LG +PLH AA G +D + LLL++
Sbjct: 697 TTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKN 756
Query: 276 GASIHDRDAKGETPISIAHRLNH 298
GAS ++ + G TP++IA RL +
Sbjct: 757 GASPNEVSSDGTTPLAIAKRLGY 779
Score = 58.9 bits (141), Expect = 6e-09
Identities = 39/111 (35%), Positives = 57/111 (51%), Gaps = 2/111 (1%)
Query: 221 FVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIH 280
F L++A + H ++ LL+ GAS + + G TPLHVA+ MG + LLQ GAS +
Sbjct: 372 FTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPN 431
Query: 281 DRDAKGETPISIAHRLNHTLSERQMVLLHRIAKSGIRDLNDLVMKNALQRV 331
+ K ETP+ +A R HT E LL AK + +D + R+
Sbjct: 432 VSNVKVETPLHMAARAGHT--EVAKYLLQNKAKVNAKAKDDQTPLHCAARI 480
Score = 57.4 bits (137), Expect = 2e-08
Identities = 35/97 (36%), Positives = 51/97 (52%), Gaps = 2/97 (2%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L+ A+ GH + LL+HGA +++ G +P+H+AA DC+ LLLQ+ A I D
Sbjct: 276 LHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDIT 335
Query: 284 AKGETPISIAHRLNHTLSERQMVLLHRIAKSGIRDLN 320
TP+ +A H + VLL + AK R LN
Sbjct: 336 LDHLTPLHVAAHCGHHRVAK--VLLDKGAKPNSRALN 370
Score = 53.5 bits (127), Expect = 3e-07
Identities = 30/89 (33%), Positives = 52/89 (58%), Gaps = 2/89 (2%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L++A+ GH + +YLL++ A +++ +TPLH AA +G ++ + LLL++ A+ +
Sbjct: 441 LHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLAT 500
Query: 284 AKGETPISIAHRLNHTLSERQMVLLHRIA 312
G TP+ IA R H E + LL + A
Sbjct: 501 TAGHTPLHIAAREGHV--ETVLALLEKEA 527
Score = 53.1 bits (126), Expect = 3e-07
Identities = 29/83 (34%), Positives = 45/83 (54%)
Query: 217 SQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHG 276
++ L+VAS GH V+ LL+ GAS + TPLH+AA G ++ LLQ+
Sbjct: 401 TESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNK 460
Query: 277 ASIHDRDAKGETPISIAHRLNHT 299
A ++ + +TP+ A R+ HT
Sbjct: 461 AKVNAKAKDDQTPLHCAARIGHT 483
Score = 52.8 bits (125), Expect = 5e-07
Identities = 30/85 (35%), Positives = 46/85 (54%)
Query: 214 HWTSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLL 273
++T Q L++AS RG+ V+ LL+ GA +++ TPLH AA G +LL
Sbjct: 233 NFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILL 292
Query: 274 QHGASIHDRDAKGETPISIAHRLNH 298
HGA I + G +PI +A + +H
Sbjct: 293 DHGAPIQAKTKNGLSPIHMAAQGDH 317
Score = 52.0 bits (123), Expect = 8e-07
Identities = 30/75 (40%), Positives = 41/75 (54%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L+VA+H GH + LL+ GA SR+ G TPLH+A + LLL+ GASI
Sbjct: 342 LHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVT 401
Query: 284 AKGETPISIAHRLNH 298
G TP+ +A + H
Sbjct: 402 ESGLTPLHVASFMGH 416
Score = 52.0 bits (123), Expect = 8e-07
Identities = 36/103 (34%), Positives = 54/103 (52%), Gaps = 8/103 (7%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L+VA H + D V+ LL G S S + G TPLH+AA + + LLQ+G S +
Sbjct: 573 LHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAES 632
Query: 284 AKGETPISIAHRLNHTLSERQMVLLHRIA------KSGIRDLN 320
+G TP+ +A + H +E +LL + A KSG+ L+
Sbjct: 633 VQGVTPLHLAAQEGH--AEMVALLLSKQANGNLGNKSGLTPLH 673
Score = 50.4 bits (119), Expect = 2e-06
Identities = 29/82 (35%), Positives = 40/82 (48%)
Query: 217 SQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHG 276
S+ F L++A+H + + Q LL GAS G TPLH+A+ G + LLL G
Sbjct: 203 SKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRG 262
Query: 277 ASIHDRDAKGETPISIAHRLNH 298
A I + TP+ A R H
Sbjct: 263 AQIETKTKDELTPLHCAARNGH 284
Score = 50.1 bits (118), Expect = 3e-06
Identities = 24/76 (31%), Positives = 40/76 (52%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L++ + GH L++HG + + +G TPLHVA+ G + LLQH A ++ +
Sbjct: 672 LHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKT 731
Query: 284 AKGETPISIAHRLNHT 299
G +P+ A + HT
Sbjct: 732 KLGYSPLHQAAQQGHT 747
Score = 49.7 bits (117), Expect = 4e-06
Identities = 38/114 (33%), Positives = 57/114 (50%), Gaps = 6/114 (5%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L+ A+ GH + V+ LLE+ A+ + G TPLH+AA G + ++ LL+ AS
Sbjct: 474 LHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMT 533
Query: 284 AKGETPISIAH-----RLNHTLSERQMVLLHRIAKSGIRDLNDLVMKNALQRVK 332
KG TP+ +A R+ L ER + K+G+ L+ V N L VK
Sbjct: 534 KKGFTPLHVAAKYGKVRVAELLLERD-AHPNAAGKNGLTPLHVAVHHNNLDIVK 586
Score = 49.3 bits (116), Expect = 5e-06
Identities = 32/109 (29%), Positives = 52/109 (47%), Gaps = 7/109 (6%)
Query: 197 SFYRTANS-------EHFEGEKWKHWTSQRAFVALYVASHRGHFDAVQYLLEHGASCLSR 249
SF R A S +H + +Q L++AS GH V LL +
Sbjct: 15 SFLRAARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETT 74
Query: 250 SPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRDAKGETPISIAHRLNH 298
+ G T LH+AA G+ + + L+ +GA+++ + KG TP+ +A + NH
Sbjct: 75 TKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENH 123
Score = 48.9 bits (115), Expect = 7e-06
Identities = 43/135 (31%), Positives = 62/135 (45%), Gaps = 17/135 (12%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
+++A+ H D V+ LL++ A + TPLHVAA G +LL GA + R
Sbjct: 309 IHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRA 368
Query: 284 AKGETPISIAHRLNHTLSERQMVLLHR-------IAKSGIRDLNDL-------VMKNALQ 329
G TP+ IA + NH R M LL + + +SG+ L+ ++KN LQ
Sbjct: 369 LNGFTPLHIACKKNHV---RVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQ 425
Query: 330 RVKSGFRSEKMTMTP 344
R S S TP
Sbjct: 426 RGASPNVSNVKVETP 440
Score = 48.5 bits (114), Expect = 9e-06
Identities = 30/90 (33%), Positives = 42/90 (46%)
Query: 217 SQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHG 276
+++ F L+VA+ G + LLE A + G TPLHVA D + LLL G
Sbjct: 533 TKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRG 592
Query: 277 ASIHDRDAKGETPISIAHRLNHTLSERQMV 306
S H G TP+ IA + N R ++
Sbjct: 593 GSPHSPAWNGYTPLHIAAKQNQVEVARSLL 622
Score = 48.1 bits (113), Expect = 1e-05
Identities = 25/83 (30%), Positives = 50/83 (60%)
Query: 216 TSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQH 275
T+++ AL++A+ G + V+ L+ +GA+ ++S G TPL++AA + + LL++
Sbjct: 74 TTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLEN 133
Query: 276 GASIHDRDAKGETPISIAHRLNH 298
GA+ + G TP+++A + H
Sbjct: 134 GANQNVATEDGFTPLAVALQQGH 156
Score = 46.6 bits (109), Expect = 3e-05
Identities = 24/85 (28%), Positives = 45/85 (52%)
Query: 214 HWTSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLL 273
H + + L++A+ + + + LL++G S + S G TPLH+AA G ++ + LLL
Sbjct: 596 HSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLL 655
Query: 274 QHGASIHDRDAKGETPISIAHRLNH 298
A+ + + G TP+ + + H
Sbjct: 656 SKQANGNLGNKSGLTPLHLVAQEGH 680
Score = 45.1 bits (105), Expect = 1e-04
Identities = 22/60 (36%), Positives = 35/60 (58%)
Query: 217 SQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHG 276
SQ+ F LY+A+ H + V++LLE+GA+ + G TPL VA G + + L+ +G
Sbjct: 108 SQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYG 167
Score = 44.7 bits (104), Expect = 1e-04
Identities = 34/125 (27%), Positives = 56/125 (44%), Gaps = 15/125 (12%)
Query: 217 SQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHG 276
S + L++A+ GH + V LL A+ + G TPLH+ A G +L++HG
Sbjct: 632 SVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHG 691
Query: 277 ASIHDRDAKGETPISIAH-----RLNHTLSERQMVL----------LHRIAKSGIRDLND 321
+ G TP+ +A +L L + Q + LH+ A+ G D+
Sbjct: 692 VMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVT 751
Query: 322 LVMKN 326
L++KN
Sbjct: 752 LLLKN 756
Score = 42.0 bits (97), Expect = 8e-04
Identities = 41/160 (25%), Positives = 63/160 (39%), Gaps = 38/160 (23%)
Query: 199 YRTANSEHFEGEKW-------KHWTSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSP 251
Y A H E K+ ++ ++ F L VA +GH + V +L+ +G R P
Sbjct: 116 YMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLP 175
Query: 252 L-----------------------------GRTPLHVAAAMGRSDCIILLLQHGASIHDR 282
G TPLH+AA + LLL GAS++
Sbjct: 176 ALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFT 235
Query: 283 DAKGETPISIAHRLNHTLSERQMVLLHRIAKSGIRDLNDL 322
G TP+ IA R + + R +LL R A+ + ++L
Sbjct: 236 PQNGITPLHIASRRGNVIMVR--LLLDRGAQIETKTKDEL 273
>gi|157743284 ankyrin repeat domain 52 [Homo sapiens]
Length = 1076
Score = 61.6 bits (148), Expect = 1e-09
Identities = 34/83 (40%), Positives = 43/83 (51%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L +A GH D V LLE G++ + GRT LH A G DC+ LL H A + RD
Sbjct: 692 LMLAIMNGHVDCVHLLLEKGSTADAADLRGRTALHRGAVTGCEDCLAALLDHDAFVLCRD 751
Query: 284 AKGETPISIAHRLNHTLSERQMV 306
KG TPI +A HT R ++
Sbjct: 752 FKGRTPIHLASACGHTAVLRTLL 774
Score = 55.5 bits (132), Expect = 7e-08
Identities = 27/70 (38%), Positives = 39/70 (55%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L+ A+ G+ + + LL GA R GRTPLH AAA G C + L+ GA +++ D
Sbjct: 427 LHAAASGGNVECLNLLLSSGADLRRRDKFGRTPLHYAAANGSYQCAVTLVTAGAGVNEAD 486
Query: 284 AKGETPISIA 293
KG +P+ A
Sbjct: 487 CKGCSPLHYA 496
Score = 48.9 bits (115), Expect = 7e-06
Identities = 24/76 (31%), Positives = 42/76 (55%)
Query: 218 QRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGA 277
++ + L+ A+ G + V+YLL GA + G T LH+A +G+ I L+ GA
Sbjct: 204 RKGYGLLHTAAASGQIEVVKYLLRMGAEIDEPNAFGNTALHIACYLGQDAVAIELVNAGA 263
Query: 278 SIHDRDAKGETPISIA 293
+++ + KG TP+ +A
Sbjct: 264 NVNQPNDKGFTPLHVA 279
Score = 48.1 bits (113), Expect = 1e-05
Identities = 34/102 (33%), Positives = 55/102 (53%), Gaps = 8/102 (7%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L++A++ GH +A++ L E + R GRT L +A G ++C+ +L HGAS ++
Sbjct: 589 LHLAAYNGHCEALKTLAETLVNLDVRDHKGRTALFLATERGSTECVEVLTAHGASALIKE 648
Query: 284 AKGE-TPISIAHRLNHTLSERQMVLLHRIAKSGIR-DLNDLV 323
K + TP+ A HT S LH + SG R D+ D++
Sbjct: 649 RKRKWTPLHAAAASGHTDS------LHLLIDSGERADITDVM 684
Score = 47.4 bits (111), Expect = 2e-05
Identities = 30/86 (34%), Positives = 47/86 (54%), Gaps = 3/86 (3%)
Query: 217 SQRAFVALYVA--SHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQ 274
+ + F L+VA S G ++ L+ +GA +S G++PLH+AA GR +L+Q
Sbjct: 269 NDKGFTPLHVAAVSTNGAL-CLELLVNNGADVNYQSKEGKSPLHMAAIHGRFTRSQILIQ 327
Query: 275 HGASIHDRDAKGETPISIAHRLNHTL 300
+G+ I D G TP+ +A R H L
Sbjct: 328 NGSEIDCADKFGNTPLHVAARYGHEL 353
Score = 47.0 bits (110), Expect = 3e-05
Identities = 26/70 (37%), Positives = 39/70 (55%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L+ A++ G +Q LL GA+ ++ L TPLH AAA + LLL H A ++ RD
Sbjct: 45 LHAAAYVGDVPILQLLLMSGANVNAKDTLWLTPLHRAAASRNEKVLGLLLAHSADVNARD 104
Query: 284 AKGETPISIA 293
+TP+ +A
Sbjct: 105 KLWQTPLHVA 114
Score = 45.8 bits (107), Expect = 6e-05
Identities = 26/64 (40%), Positives = 34/64 (53%)
Query: 223 ALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDR 282
AL+ A H GH + V LL GAS R PLH AA +G + + LL+ GA + +
Sbjct: 143 ALHHAVHSGHLETVNLLLNKGASLNVCDKKERQPLHWAAFLGHLEVLKLLVARGADLGCK 202
Query: 283 DAKG 286
D KG
Sbjct: 203 DRKG 206
Score = 44.3 bits (103), Expect = 2e-04
Identities = 23/57 (40%), Positives = 32/57 (56%)
Query: 237 QYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRDAKGETPISIA 293
+++L G + LGRT LH AA+ G +C+ LLL GA + RD G TP+ A
Sbjct: 407 EHVLSAGFDINTPDNLGRTCLHAAASGGNVECLNLLLSSGADLRRRDKFGRTPLHYA 463
Score = 44.3 bits (103), Expect = 2e-04
Identities = 36/133 (27%), Positives = 60/133 (45%), Gaps = 19/133 (14%)
Query: 162 IISLCIWHHDGWTELVLAAVEGDPSKLSCLGLTEDSFYRTAN-SEHFEGEKWKHWTSQRA 220
+++L + H G T L LA G + L TA+ + E+ + WT
Sbjct: 608 LVNLDVRDHKGRTALFLATERGSTECVEVL---------TAHGASALIKERKRKWTP--- 655
Query: 221 FVALYVASHRGHFDAVQYLLEHGASCLSRSPL---GRTPLHVAAAMGRSDCIILLLQHGA 277
L+ A+ GH D++ L++ G + G+TPL +A G DC+ LLL+ G+
Sbjct: 656 ---LHAAAASGHTDSLHLLIDSGERADITDVMDAYGQTPLMLAIMNGHVDCVHLLLEKGS 712
Query: 278 SIHDRDAKGETPI 290
+ D +G T +
Sbjct: 713 TADAADLRGRTAL 725
Score = 42.4 bits (98), Expect = 6e-04
Identities = 34/90 (37%), Positives = 48/90 (53%), Gaps = 6/90 (6%)
Query: 224 LYVASHRGHFDAVQYLLEHGA-SCLSRSPLGRTPLHVAAAMGRSDCIILLLQH-GASI-H 280
++ AS+ GH D ++ LLEH S L +P TPLH A + +LL GA I +
Sbjct: 795 MHWASYTGHEDCLELLLEHSPFSYLEGNPF--TPLHCAVINNQDSTTEMLLGALGAKIVN 852
Query: 281 DRDAKGETPISIAHRLNHTLSERQMVLLHR 310
RDAKG TP+ A +S +M+L H+
Sbjct: 853 SRDAKGRTPLHAA-AFADNVSGLRMLLQHQ 881
Score = 41.6 bits (96), Expect = 0.001
Identities = 24/70 (34%), Positives = 38/70 (54%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L+ A+ GH + ++ L+ GA + G LH AAA G+ + + LL+ GA I + +
Sbjct: 177 LHWAAFLGHLEVLKLLVARGADLGCKDRKGYGLLHTAAASGQIEVVKYLLRMGAEIDEPN 236
Query: 284 AKGETPISIA 293
A G T + IA
Sbjct: 237 AFGNTALHIA 246
Score = 41.2 bits (95), Expect = 0.001
Identities = 29/84 (34%), Positives = 40/84 (47%), Gaps = 4/84 (4%)
Query: 219 RAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGAS 278
R AL+ + G D + LL+H A L R GRTP+H+A+A G + + LLQ S
Sbjct: 720 RGRTALHRGAVTGCEDCLAALLDHDAFVLCRDFKGRTPIHLASACGHTAVLRTLLQAALS 779
Query: 279 IHDRDA----KGETPISIAHRLNH 298
DA G +P+ A H
Sbjct: 780 TDPLDAGVDYSGYSPMHWASYTGH 803
Score = 40.8 bits (94), Expect = 0.002
Identities = 24/80 (30%), Positives = 38/80 (47%)
Query: 214 HWTSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLL 273
++ S+ L++A+ G F Q L+++G+ G TPLHVAA G I L+
Sbjct: 300 NYQSKEGKSPLHMAAIHGRFTRSQILIQNGSEIDCADKFGNTPLHVAARYGHELLISTLM 359
Query: 274 QHGASIHDRDAKGETPISIA 293
+GA R P+ +A
Sbjct: 360 TNGADTARRGIHDMFPLHLA 379
Score = 39.7 bits (91), Expect = 0.004
Identities = 23/72 (31%), Positives = 42/72 (58%), Gaps = 1/72 (1%)
Query: 223 ALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAA-AMGRSDCIILLLQHGASIHD 281
AL++A + G L+ GA+ + G TPLHVAA + + C+ LL+ +GA ++
Sbjct: 242 ALHIACYLGQDAVAIELVNAGANVNQPNDKGFTPLHVAAVSTNGALCLELLVNNGADVNY 301
Query: 282 RDAKGETPISIA 293
+ +G++P+ +A
Sbjct: 302 QSKEGKSPLHMA 313
Score = 37.0 bits (84), Expect = 0.026
Identities = 22/78 (28%), Positives = 42/78 (53%), Gaps = 2/78 (2%)
Query: 218 QRAFVALYVASHRGHFDAVQYLLEHGASCLS--RSPLGRTPLHVAAAMGRSDCIILLLQH 275
++ + A++ A+ G+ ++ LLE +CL S + +PLH+AA G + + L +
Sbjct: 548 RQGYTAVHYAAAYGNRQNLELLLEMSFNCLEDVESTIPVSPLHLAAYNGHCEALKTLAET 607
Query: 276 GASIHDRDAKGETPISIA 293
++ RD KG T + +A
Sbjct: 608 LVNLDVRDHKGRTALFLA 625
Score = 36.6 bits (83), Expect = 0.034
Identities = 24/71 (33%), Positives = 36/71 (50%), Gaps = 5/71 (7%)
Query: 223 ALYVASHRGHFDAVQYLLEH----GASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGAS 278
AL++A +GH +L G + S L + PLH+AA G + + LL HGA+
Sbjct: 928 ALHLACSKGHEKCALMILAETQDLGLINATNSAL-QMPLHIAARNGLASVVQALLSHGAT 986
Query: 279 IHDRDAKGETP 289
+ D +G TP
Sbjct: 987 VLAVDEEGHTP 997
Score = 35.4 bits (80), Expect = 0.075
Identities = 21/55 (38%), Positives = 32/55 (58%), Gaps = 3/55 (5%)
Query: 254 RTPLHVAAAMGRSDCIILLLQHGASIHDRDAKGETPISIAHRLNHTLSERQMVLL 308
RTPLH AA +G + LLL GA+++ +D TP+ HR + +E+ + LL
Sbjct: 42 RTPLHAAAYVGDVPILQLLLMSGANVNAKDTLWLTPL---HRAAASRNEKVLGLL 93
Score = 35.4 bits (80), Expect = 0.075
Identities = 20/53 (37%), Positives = 26/53 (49%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHG 276
L+VA+ GH + L+ +GA R PLH+A G SDC LL G
Sbjct: 343 LHVAARYGHELLISTLMTNGADTARRGIHDMFPLHLAVLFGFSDCCRKLLSSG 395
Score = 35.0 bits (79), Expect = 0.098
Identities = 26/80 (32%), Positives = 38/80 (47%), Gaps = 2/80 (2%)
Query: 239 LLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRDAKGETPISIAHRLNH 298
LL H A +R L +TPLHVAAA + C L +S++ D G + + A H
Sbjct: 93 LLAHSADVNARDKLWQTPLHVAAANRATKCAEALAPLLSSLNVADRSGRSALHHAVHSGH 152
Query: 299 TLSERQMVLLHRIAKSGIRD 318
E +LL++ A + D
Sbjct: 153 L--ETVNLLLNKGASLNVCD 170
Score = 35.0 bits (79), Expect = 0.098
Identities = 23/70 (32%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
Query: 216 TSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTP-LHVAAAMGRSDCIILLLQ 274
T+ + L++A+ G VQ LL HGA+ L+ G TP L A +DC+ L+L
Sbjct: 957 TNSALQMPLHIAARNGLASVVQALLSHGATVLAVDEEGHTPALACAPNKDVADCLALILS 1016
Query: 275 HGASIHDRDA 284
+DA
Sbjct: 1017 TMKPFPPKDA 1026
Score = 33.5 bits (75), Expect = 0.29
Identities = 24/66 (36%), Positives = 33/66 (50%), Gaps = 2/66 (3%)
Query: 253 GRTPLHVAAAMGRSDCIILLLQHGASIHDRDAKGETPISIAHRLNHTLSERQMVLLHRIA 312
GR+ LH A G + + LLL GAS++ D K P+ A L H E +L+ R A
Sbjct: 140 GRSALHHAVHSGHLETVNLLLNKGASLNVCDKKERQPLHWAAFLGHL--EVLKLLVARGA 197
Query: 313 KSGIRD 318
G +D
Sbjct: 198 DLGCKD 203
Score = 32.3 bits (72), Expect = 0.64
Identities = 20/62 (32%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 233 FDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRDAKGETPISI 292
F +++LL++GA R G T +H AAA G + LLL+ + + D + P+S
Sbjct: 530 FFCLEFLLDNGADPSLRDRQGYTAVHYAAAYGNRQNLELLLEMSFNCLE-DVESTIPVSP 588
Query: 293 AH 294
H
Sbjct: 589 LH 590
Score = 32.0 bits (71), Expect = 0.83
Identities = 31/126 (24%), Positives = 51/126 (40%), Gaps = 7/126 (5%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHG-ASIHDR 282
L+ A+ + ++ LL+H A + GRT L AA G++ + LL G A +
Sbjct: 862 LHAAAFADNVSGLRMLLQHQAEVNATDHTGRTALMTAAENGQTAAVEFLLYRGKADLTVL 921
Query: 283 DAKGETPISIAHRLNH------TLSERQMVLLHRIAKSGIRDLNDLVMKNALQRVKSGFR 336
D T + +A H L+E Q + L S ++ + +N L V
Sbjct: 922 DENKNTALHLACSKGHEKCALMILAETQDLGLINATNSALQMPLHIAARNGLASVVQALL 981
Query: 337 SEKMTM 342
S T+
Sbjct: 982 SHGATV 987
>gi|188595682 ankyrin 2 isoform 3 [Homo sapiens]
Length = 1863
Score = 61.2 bits (147), Expect = 1e-09
Identities = 36/91 (39%), Positives = 50/91 (54%), Gaps = 5/91 (5%)
Query: 213 KHWTSQRA-----FVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSD 267
KH Q A + L VA H G+ V +LL+ GA+ +++ G TPLH AA G +
Sbjct: 695 KHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTH 754
Query: 268 CIILLLQHGASIHDRDAKGETPISIAHRLNH 298
I +LLQHGA + A G T ++IA RL +
Sbjct: 755 IINVLLQHGAKPNATTANGNTALAIAKRLGY 785
Score = 58.2 bits (139), Expect = 1e-08
Identities = 40/122 (32%), Positives = 61/122 (50%), Gaps = 6/122 (4%)
Query: 216 TSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQH 275
T++ F L++A+H G+ + LL GA+ + G TPLHVA+ G ++ + LLL
Sbjct: 208 TTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDR 267
Query: 276 GASIHDRDAKGETPISIAHRLNH-----TLSERQMVLLHRIAKSGIRDLNDLVMKNALQR 330
G I + G TP+ A R H L ER LL R K+G+ L+ + ++
Sbjct: 268 GGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLAR-TKNGLSPLHMAAQGDHVEC 326
Query: 331 VK 332
VK
Sbjct: 327 VK 328
Score = 57.8 bits (138), Expect = 1e-08
Identities = 35/109 (32%), Positives = 60/109 (55%), Gaps = 7/109 (6%)
Query: 197 SFYRTANS-------EHFEGEKWKHWTSQRAFVALYVASHRGHFDAVQYLLEHGASCLSR 249
SF R A + E+ +G + +Q AL++A+ GH VQ LL G+S S
Sbjct: 13 SFLRAARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSA 72
Query: 250 SPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRDAKGETPISIAHRLNH 298
+ G T LH+A+ G+++ + +L++ GA+I+ + G TP+ +A + NH
Sbjct: 73 TKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENH 121
Score = 56.2 bits (134), Expect = 4e-08
Identities = 28/75 (37%), Positives = 47/75 (62%)
Query: 221 FVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIH 280
F L++A + ++ L+++GAS + + G TP+HVAA MG + ++LLLQ+GAS
Sbjct: 378 FTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPD 437
Query: 281 DRDAKGETPISIAHR 295
+ +GET + +A R
Sbjct: 438 VTNIRGETALHMAAR 452
Score = 56.2 bits (134), Expect = 4e-08
Identities = 45/144 (31%), Positives = 71/144 (49%), Gaps = 19/144 (13%)
Query: 216 TSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQH 275
T+ R AL++A+ G + V+ LL +GA +R+ +TPLH+A+ +G+++ + LLLQH
Sbjct: 439 TNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQH 498
Query: 276 GASIHDRDAKGETPISIAHR--------------LNHTLSERQ-MVLLHRIAKSGIRDLN 320
A G TP+ I+ R H+L+ ++ LH AK G D
Sbjct: 499 MAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLD-- 556
Query: 321 DLVMKNALQRVKSGFRSEKMTMTP 344
V K LQR + + K +TP
Sbjct: 557 --VAKLLLQRRAAADSAGKNGLTP 578
Score = 55.5 bits (132), Expect = 7e-08
Identities = 41/139 (29%), Positives = 64/139 (46%), Gaps = 18/139 (12%)
Query: 217 SQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHG 276
+++ F L+VA+ G D + LL+ A+ S G TPLHVAA +LLL+ G
Sbjct: 539 TKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKG 598
Query: 277 ASIHDRDAKGETPISIAHRLN---------------HTLSERQMVLLHRIAKSGIRDLND 321
AS H G TP+ IA + N + ++++ + LH ++ G D+
Sbjct: 599 ASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVT 658
Query: 322 LVM---KNALQRVKSGFRS 337
L++ N KSG S
Sbjct: 659 LLLDKGANIHMSTKSGLTS 677
Score = 54.7 bits (130), Expect = 1e-07
Identities = 30/76 (39%), Positives = 45/76 (59%)
Query: 223 ALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDR 282
AL+VA+H GH+ + LL+ A+ +R+ G TPLH+A R + LL+++GASI
Sbjct: 347 ALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAI 406
Query: 283 DAKGETPISIAHRLNH 298
G TPI +A + H
Sbjct: 407 TESGLTPIHVAAFMGH 422
Score = 54.3 bits (129), Expect = 2e-07
Identities = 29/84 (34%), Positives = 48/84 (57%)
Query: 215 WTSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQ 274
+T++ L+VAS RG+ + V+ LL+ G +++ G TPLH AA G + LLL+
Sbjct: 240 FTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLE 299
Query: 275 HGASIHDRDAKGETPISIAHRLNH 298
GA + R G +P+ +A + +H
Sbjct: 300 RGAPLLARTKNGLSPLHMAAQGDH 323
Score = 54.3 bits (129), Expect = 2e-07
Identities = 38/116 (32%), Positives = 55/116 (47%), Gaps = 10/116 (8%)
Query: 221 FVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIH 280
+ L++++ G D LLE GA+ + G TPLHVAA G D LLLQ A+
Sbjct: 510 YTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAAD 569
Query: 281 DRDAKGETPISIAHRLNHTLSERQMVLL-------HRIAKSGIRDLNDLVMKNALQ 329
G TP+ +A H +++ +LL H AK+G L+ KN +Q
Sbjct: 570 SAGKNGLTPLHVA---AHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQ 622
Score = 53.9 bits (128), Expect = 2e-07
Identities = 46/166 (27%), Positives = 83/166 (50%), Gaps = 20/166 (12%)
Query: 153 KFHDVVPGGI-ISLCIWHHDGWTELVLAAVEGDPSKLSCLGLTEDSFYRTANSEHFEGEK 211
K + + GGI I+ C + +G L LAA EG +GL ++ R ++ +
Sbjct: 25 KVVEYLKGGIDINTC--NQNGLNALHLAAKEGH------VGLVQELLGRGSSVDS----- 71
Query: 212 WKHWTSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIIL 271
+++ AL++AS G + V+ L++ GA+ ++S G TPL++AA D +
Sbjct: 72 ----ATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKY 127
Query: 272 LLQHGASIHDRDAKGETPISIAHRLNHTLSERQMVLLHRIAKSGIR 317
LL++GA+ G TP+++A + H ++ +LL K +R
Sbjct: 128 LLENGANQSTATEDGFTPLAVALQQGH--NQAVAILLENDTKGKVR 171
Score = 53.5 bits (127), Expect = 3e-07
Identities = 33/96 (34%), Positives = 54/96 (56%), Gaps = 2/96 (2%)
Query: 217 SQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHG 276
++ ++VA+ GH + V LL++GAS + G T LH+AA G+ + + LL++G
Sbjct: 407 TESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNG 466
Query: 277 ASIHDRDAKGETPISIAHRLNHTLSERQMVLLHRIA 312
A + R + +TP+ IA RL T E +LL +A
Sbjct: 467 ALVDARAREEQTPLHIASRLGKT--EIVQLLLQHMA 500
Score = 53.1 bits (126), Expect = 3e-07
Identities = 32/112 (28%), Positives = 58/112 (51%), Gaps = 8/112 (7%)
Query: 217 SQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHG 276
SQ F LY+A+ H D V+YLLE+GA+ + + G TPL VA G + + +LL++
Sbjct: 106 SQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLEND 165
Query: 277 A-------SIHDRDAKGET-PISIAHRLNHTLSERQMVLLHRIAKSGIRDLN 320
++H K +T ++ + +H + ++++R +SG L+
Sbjct: 166 TKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLH 217
Score = 53.1 bits (126), Expect = 3e-07
Identities = 34/97 (35%), Positives = 49/97 (50%), Gaps = 2/97 (2%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L+ A+ GH V+ LLE GA L+R+ G +PLH+AA +C+ LLQH A + D
Sbjct: 282 LHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVT 341
Query: 284 AKGETPISIAHRLNHTLSERQMVLLHRIAKSGIRDLN 320
T + +A H + +LL + A R LN
Sbjct: 342 LDYLTALHVAAHCGHYRVTK--LLLDKRANPNARALN 376
Score = 51.2 bits (121), Expect = 1e-06
Identities = 26/80 (32%), Positives = 42/80 (52%)
Query: 214 HWTSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLL 273
H T++ + L++A+ + LL +GA + G TPLH+A+ G +D + LLL
Sbjct: 602 HATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLL 661
Query: 274 QHGASIHDRDAKGETPISIA 293
GA+IH G T + +A
Sbjct: 662 DKGANIHMSTKSGLTSLHLA 681
Score = 48.1 bits (113), Expect = 1e-05
Identities = 25/86 (29%), Positives = 44/86 (51%)
Query: 214 HWTSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLL 273
H +++ +L++A+ + L +HGA + + LG TPL VA G + LL
Sbjct: 668 HMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLL 727
Query: 274 QHGASIHDRDAKGETPISIAHRLNHT 299
+ GA+++ + G TP+ A + HT
Sbjct: 728 KQGANVNAKTKNGYTPLHQAAQQGHT 753
Score = 45.1 bits (105), Expect = 1e-04
Identities = 25/77 (32%), Positives = 40/77 (51%)
Query: 217 SQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHG 276
+++ L++AS GH D V LL+ GA+ + G T LH+AA + + +L +HG
Sbjct: 638 TKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHG 697
Query: 277 ASIHDRDAKGETPISIA 293
A G TP+ +A
Sbjct: 698 ADQDAHTKLGYTPLIVA 714
Score = 37.7 bits (86), Expect = 0.015
Identities = 26/74 (35%), Positives = 38/74 (51%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L++A+ H + V++LL+H A + T LHVAA G LLL A+ + R
Sbjct: 315 LHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARA 374
Query: 284 AKGETPISIAHRLN 297
G TP+ IA + N
Sbjct: 375 LNGFTPLHIACKKN 388
>gi|52426737 ankyrin 2 isoform 2 [Homo sapiens]
Length = 1872
Score = 61.2 bits (147), Expect = 1e-09
Identities = 36/91 (39%), Positives = 50/91 (54%), Gaps = 5/91 (5%)
Query: 213 KHWTSQRA-----FVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSD 267
KH Q A + L VA H G+ V +LL+ GA+ +++ G TPLH AA G +
Sbjct: 716 KHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTH 775
Query: 268 CIILLLQHGASIHDRDAKGETPISIAHRLNH 298
I +LLQHGA + A G T ++IA RL +
Sbjct: 776 IINVLLQHGAKPNATTANGNTALAIAKRLGY 806
Score = 58.2 bits (139), Expect = 1e-08
Identities = 40/122 (32%), Positives = 61/122 (50%), Gaps = 6/122 (4%)
Query: 216 TSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQH 275
T++ F L++A+H G+ + LL GA+ + G TPLHVA+ G ++ + LLL
Sbjct: 229 TTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDR 288
Query: 276 GASIHDRDAKGETPISIAHRLNH-----TLSERQMVLLHRIAKSGIRDLNDLVMKNALQR 330
G I + G TP+ A R H L ER LL R K+G+ L+ + ++
Sbjct: 289 GGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLAR-TKNGLSPLHMAAQGDHVEC 347
Query: 331 VK 332
VK
Sbjct: 348 VK 349
Score = 57.8 bits (138), Expect = 1e-08
Identities = 35/109 (32%), Positives = 60/109 (55%), Gaps = 7/109 (6%)
Query: 197 SFYRTANS-------EHFEGEKWKHWTSQRAFVALYVASHRGHFDAVQYLLEHGASCLSR 249
SF R A + E+ +G + +Q AL++A+ GH VQ LL G+S S
Sbjct: 34 SFLRAARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSA 93
Query: 250 SPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRDAKGETPISIAHRLNH 298
+ G T LH+A+ G+++ + +L++ GA+I+ + G TP+ +A + NH
Sbjct: 94 TKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENH 142
Score = 56.2 bits (134), Expect = 4e-08
Identities = 28/75 (37%), Positives = 47/75 (62%)
Query: 221 FVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIH 280
F L++A + ++ L+++GAS + + G TP+HVAA MG + ++LLLQ+GAS
Sbjct: 399 FTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPD 458
Query: 281 DRDAKGETPISIAHR 295
+ +GET + +A R
Sbjct: 459 VTNIRGETALHMAAR 473
Score = 56.2 bits (134), Expect = 4e-08
Identities = 45/144 (31%), Positives = 71/144 (49%), Gaps = 19/144 (13%)
Query: 216 TSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQH 275
T+ R AL++A+ G + V+ LL +GA +R+ +TPLH+A+ +G+++ + LLLQH
Sbjct: 460 TNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQH 519
Query: 276 GASIHDRDAKGETPISIAHR--------------LNHTLSERQ-MVLLHRIAKSGIRDLN 320
A G TP+ I+ R H+L+ ++ LH AK G D
Sbjct: 520 MAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLD-- 577
Query: 321 DLVMKNALQRVKSGFRSEKMTMTP 344
V K LQR + + K +TP
Sbjct: 578 --VAKLLLQRRAAADSAGKNGLTP 599
Score = 55.5 bits (132), Expect = 7e-08
Identities = 41/139 (29%), Positives = 64/139 (46%), Gaps = 18/139 (12%)
Query: 217 SQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHG 276
+++ F L+VA+ G D + LL+ A+ S G TPLHVAA +LLL+ G
Sbjct: 560 TKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKG 619
Query: 277 ASIHDRDAKGETPISIAHRLN---------------HTLSERQMVLLHRIAKSGIRDLND 321
AS H G TP+ IA + N + ++++ + LH ++ G D+
Sbjct: 620 ASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVT 679
Query: 322 LVM---KNALQRVKSGFRS 337
L++ N KSG S
Sbjct: 680 LLLDKGANIHMSTKSGLTS 698
Score = 54.7 bits (130), Expect = 1e-07
Identities = 30/76 (39%), Positives = 45/76 (59%)
Query: 223 ALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDR 282
AL+VA+H GH+ + LL+ A+ +R+ G TPLH+A R + LL+++GASI
Sbjct: 368 ALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAI 427
Query: 283 DAKGETPISIAHRLNH 298
G TPI +A + H
Sbjct: 428 TESGLTPIHVAAFMGH 443
Score = 54.3 bits (129), Expect = 2e-07
Identities = 29/84 (34%), Positives = 48/84 (57%)
Query: 215 WTSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQ 274
+T++ L+VAS RG+ + V+ LL+ G +++ G TPLH AA G + LLL+
Sbjct: 261 FTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLE 320
Query: 275 HGASIHDRDAKGETPISIAHRLNH 298
GA + R G +P+ +A + +H
Sbjct: 321 RGAPLLARTKNGLSPLHMAAQGDH 344
Score = 54.3 bits (129), Expect = 2e-07
Identities = 38/116 (32%), Positives = 55/116 (47%), Gaps = 10/116 (8%)
Query: 221 FVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIH 280
+ L++++ G D LLE GA+ + G TPLHVAA G D LLLQ A+
Sbjct: 531 YTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAAD 590
Query: 281 DRDAKGETPISIAHRLNHTLSERQMVLL-------HRIAKSGIRDLNDLVMKNALQ 329
G TP+ +A H +++ +LL H AK+G L+ KN +Q
Sbjct: 591 SAGKNGLTPLHVA---AHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQ 643
Score = 53.9 bits (128), Expect = 2e-07
Identities = 46/166 (27%), Positives = 83/166 (50%), Gaps = 20/166 (12%)
Query: 153 KFHDVVPGGI-ISLCIWHHDGWTELVLAAVEGDPSKLSCLGLTEDSFYRTANSEHFEGEK 211
K + + GGI I+ C + +G L LAA EG +GL ++ R ++ +
Sbjct: 46 KVVEYLKGGIDINTC--NQNGLNALHLAAKEGH------VGLVQELLGRGSSVDS----- 92
Query: 212 WKHWTSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIIL 271
+++ AL++AS G + V+ L++ GA+ ++S G TPL++AA D +
Sbjct: 93 ----ATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKY 148
Query: 272 LLQHGASIHDRDAKGETPISIAHRLNHTLSERQMVLLHRIAKSGIR 317
LL++GA+ G TP+++A + H ++ +LL K +R
Sbjct: 149 LLENGANQSTATEDGFTPLAVALQQGH--NQAVAILLENDTKGKVR 192
Score = 53.5 bits (127), Expect = 3e-07
Identities = 33/96 (34%), Positives = 54/96 (56%), Gaps = 2/96 (2%)
Query: 217 SQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHG 276
++ ++VA+ GH + V LL++GAS + G T LH+AA G+ + + LL++G
Sbjct: 428 TESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNG 487
Query: 277 ASIHDRDAKGETPISIAHRLNHTLSERQMVLLHRIA 312
A + R + +TP+ IA RL T E +LL +A
Sbjct: 488 ALVDARAREEQTPLHIASRLGKT--EIVQLLLQHMA 521
Score = 53.1 bits (126), Expect = 3e-07
Identities = 32/112 (28%), Positives = 58/112 (51%), Gaps = 8/112 (7%)
Query: 217 SQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHG 276
SQ F LY+A+ H D V+YLLE+GA+ + + G TPL VA G + + +LL++
Sbjct: 127 SQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLEND 186
Query: 277 A-------SIHDRDAKGET-PISIAHRLNHTLSERQMVLLHRIAKSGIRDLN 320
++H K +T ++ + +H + ++++R +SG L+
Sbjct: 187 TKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLH 238
Score = 53.1 bits (126), Expect = 3e-07
Identities = 34/97 (35%), Positives = 49/97 (50%), Gaps = 2/97 (2%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L+ A+ GH V+ LLE GA L+R+ G +PLH+AA +C+ LLQH A + D
Sbjct: 303 LHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVT 362
Query: 284 AKGETPISIAHRLNHTLSERQMVLLHRIAKSGIRDLN 320
T + +A H + +LL + A R LN
Sbjct: 363 LDYLTALHVAAHCGHYRVTK--LLLDKRANPNARALN 397
Score = 51.2 bits (121), Expect = 1e-06
Identities = 26/80 (32%), Positives = 42/80 (52%)
Query: 214 HWTSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLL 273
H T++ + L++A+ + LL +GA + G TPLH+A+ G +D + LLL
Sbjct: 623 HATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLL 682
Query: 274 QHGASIHDRDAKGETPISIA 293
GA+IH G T + +A
Sbjct: 683 DKGANIHMSTKSGLTSLHLA 702
Score = 48.1 bits (113), Expect = 1e-05
Identities = 25/86 (29%), Positives = 44/86 (51%)
Query: 214 HWTSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLL 273
H +++ +L++A+ + L +HGA + + LG TPL VA G + LL
Sbjct: 689 HMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLL 748
Query: 274 QHGASIHDRDAKGETPISIAHRLNHT 299
+ GA+++ + G TP+ A + HT
Sbjct: 749 KQGANVNAKTKNGYTPLHQAAQQGHT 774
Score = 45.1 bits (105), Expect = 1e-04
Identities = 25/77 (32%), Positives = 40/77 (51%)
Query: 217 SQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHG 276
+++ L++AS GH D V LL+ GA+ + G T LH+AA + + +L +HG
Sbjct: 659 TKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHG 718
Query: 277 ASIHDRDAKGETPISIA 293
A G TP+ +A
Sbjct: 719 ADQDAHTKLGYTPLIVA 735
Score = 37.7 bits (86), Expect = 0.015
Identities = 26/74 (35%), Positives = 38/74 (51%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L++A+ H + V++LL+H A + T LHVAA G LLL A+ + R
Sbjct: 336 LHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARA 395
Query: 284 AKGETPISIAHRLN 297
G TP+ IA + N
Sbjct: 396 LNGFTPLHIACKKN 409
>gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]
Length = 3957
Score = 61.2 bits (147), Expect = 1e-09
Identities = 36/91 (39%), Positives = 50/91 (54%), Gaps = 5/91 (5%)
Query: 213 KHWTSQRA-----FVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSD 267
KH Q A + L VA H G+ V +LL+ GA+ +++ G TPLH AA G +
Sbjct: 716 KHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTH 775
Query: 268 CIILLLQHGASIHDRDAKGETPISIAHRLNH 298
I +LLQHGA + A G T ++IA RL +
Sbjct: 776 IINVLLQHGAKPNATTANGNTALAIAKRLGY 806
Score = 58.2 bits (139), Expect = 1e-08
Identities = 40/122 (32%), Positives = 61/122 (50%), Gaps = 6/122 (4%)
Query: 216 TSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQH 275
T++ F L++A+H G+ + LL GA+ + G TPLHVA+ G ++ + LLL
Sbjct: 229 TTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDR 288
Query: 276 GASIHDRDAKGETPISIAHRLNH-----TLSERQMVLLHRIAKSGIRDLNDLVMKNALQR 330
G I + G TP+ A R H L ER LL R K+G+ L+ + ++
Sbjct: 289 GGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLAR-TKNGLSPLHMAAQGDHVEC 347
Query: 331 VK 332
VK
Sbjct: 348 VK 349
Score = 57.8 bits (138), Expect = 1e-08
Identities = 35/109 (32%), Positives = 60/109 (55%), Gaps = 7/109 (6%)
Query: 197 SFYRTANS-------EHFEGEKWKHWTSQRAFVALYVASHRGHFDAVQYLLEHGASCLSR 249
SF R A + E+ +G + +Q AL++A+ GH VQ LL G+S S
Sbjct: 34 SFLRAARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSA 93
Query: 250 SPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRDAKGETPISIAHRLNH 298
+ G T LH+A+ G+++ + +L++ GA+I+ + G TP+ +A + NH
Sbjct: 94 TKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENH 142
Score = 56.2 bits (134), Expect = 4e-08
Identities = 28/75 (37%), Positives = 47/75 (62%)
Query: 221 FVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIH 280
F L++A + ++ L+++GAS + + G TP+HVAA MG + ++LLLQ+GAS
Sbjct: 399 FTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPD 458
Query: 281 DRDAKGETPISIAHR 295
+ +GET + +A R
Sbjct: 459 VTNIRGETALHMAAR 473
Score = 56.2 bits (134), Expect = 4e-08
Identities = 45/144 (31%), Positives = 71/144 (49%), Gaps = 19/144 (13%)
Query: 216 TSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQH 275
T+ R AL++A+ G + V+ LL +GA +R+ +TPLH+A+ +G+++ + LLLQH
Sbjct: 460 TNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQH 519
Query: 276 GASIHDRDAKGETPISIAHR--------------LNHTLSERQ-MVLLHRIAKSGIRDLN 320
A G TP+ I+ R H+L+ ++ LH AK G D
Sbjct: 520 MAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLD-- 577
Query: 321 DLVMKNALQRVKSGFRSEKMTMTP 344
V K LQR + + K +TP
Sbjct: 578 --VAKLLLQRRAAADSAGKNGLTP 599
Score = 55.5 bits (132), Expect = 7e-08
Identities = 41/139 (29%), Positives = 64/139 (46%), Gaps = 18/139 (12%)
Query: 217 SQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHG 276
+++ F L+VA+ G D + LL+ A+ S G TPLHVAA +LLL+ G
Sbjct: 560 TKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKG 619
Query: 277 ASIHDRDAKGETPISIAHRLN---------------HTLSERQMVLLHRIAKSGIRDLND 321
AS H G TP+ IA + N + ++++ + LH ++ G D+
Sbjct: 620 ASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVT 679
Query: 322 LVM---KNALQRVKSGFRS 337
L++ N KSG S
Sbjct: 680 LLLDKGANIHMSTKSGLTS 698
Score = 54.7 bits (130), Expect = 1e-07
Identities = 30/76 (39%), Positives = 45/76 (59%)
Query: 223 ALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDR 282
AL+VA+H GH+ + LL+ A+ +R+ G TPLH+A R + LL+++GASI
Sbjct: 368 ALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAI 427
Query: 283 DAKGETPISIAHRLNH 298
G TPI +A + H
Sbjct: 428 TESGLTPIHVAAFMGH 443
Score = 54.3 bits (129), Expect = 2e-07
Identities = 29/84 (34%), Positives = 48/84 (57%)
Query: 215 WTSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQ 274
+T++ L+VAS RG+ + V+ LL+ G +++ G TPLH AA G + LLL+
Sbjct: 261 FTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLE 320
Query: 275 HGASIHDRDAKGETPISIAHRLNH 298
GA + R G +P+ +A + +H
Sbjct: 321 RGAPLLARTKNGLSPLHMAAQGDH 344
Score = 54.3 bits (129), Expect = 2e-07
Identities = 38/116 (32%), Positives = 55/116 (47%), Gaps = 10/116 (8%)
Query: 221 FVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIH 280
+ L++++ G D LLE GA+ + G TPLHVAA G D LLLQ A+
Sbjct: 531 YTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAAD 590
Query: 281 DRDAKGETPISIAHRLNHTLSERQMVLL-------HRIAKSGIRDLNDLVMKNALQ 329
G TP+ +A H +++ +LL H AK+G L+ KN +Q
Sbjct: 591 SAGKNGLTPLHVA---AHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQ 643
Score = 53.9 bits (128), Expect = 2e-07
Identities = 46/166 (27%), Positives = 83/166 (50%), Gaps = 20/166 (12%)
Query: 153 KFHDVVPGGI-ISLCIWHHDGWTELVLAAVEGDPSKLSCLGLTEDSFYRTANSEHFEGEK 211
K + + GGI I+ C + +G L LAA EG +GL ++ R ++ +
Sbjct: 46 KVVEYLKGGIDINTC--NQNGLNALHLAAKEGH------VGLVQELLGRGSSVDS----- 92
Query: 212 WKHWTSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIIL 271
+++ AL++AS G + V+ L++ GA+ ++S G TPL++AA D +
Sbjct: 93 ----ATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKY 148
Query: 272 LLQHGASIHDRDAKGETPISIAHRLNHTLSERQMVLLHRIAKSGIR 317
LL++GA+ G TP+++A + H ++ +LL K +R
Sbjct: 149 LLENGANQSTATEDGFTPLAVALQQGH--NQAVAILLENDTKGKVR 192
Score = 53.5 bits (127), Expect = 3e-07
Identities = 33/96 (34%), Positives = 54/96 (56%), Gaps = 2/96 (2%)
Query: 217 SQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHG 276
++ ++VA+ GH + V LL++GAS + G T LH+AA G+ + + LL++G
Sbjct: 428 TESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNG 487
Query: 277 ASIHDRDAKGETPISIAHRLNHTLSERQMVLLHRIA 312
A + R + +TP+ IA RL T E +LL +A
Sbjct: 488 ALVDARAREEQTPLHIASRLGKT--EIVQLLLQHMA 521
Score = 53.1 bits (126), Expect = 3e-07
Identities = 32/112 (28%), Positives = 58/112 (51%), Gaps = 8/112 (7%)
Query: 217 SQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHG 276
SQ F LY+A+ H D V+YLLE+GA+ + + G TPL VA G + + +LL++
Sbjct: 127 SQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLEND 186
Query: 277 A-------SIHDRDAKGET-PISIAHRLNHTLSERQMVLLHRIAKSGIRDLN 320
++H K +T ++ + +H + ++++R +SG L+
Sbjct: 187 TKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLH 238
Score = 53.1 bits (126), Expect = 3e-07
Identities = 34/97 (35%), Positives = 49/97 (50%), Gaps = 2/97 (2%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L+ A+ GH V+ LLE GA L+R+ G +PLH+AA +C+ LLQH A + D
Sbjct: 303 LHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVT 362
Query: 284 AKGETPISIAHRLNHTLSERQMVLLHRIAKSGIRDLN 320
T + +A H + +LL + A R LN
Sbjct: 363 LDYLTALHVAAHCGHYRVTK--LLLDKRANPNARALN 397
Score = 51.2 bits (121), Expect = 1e-06
Identities = 26/80 (32%), Positives = 42/80 (52%)
Query: 214 HWTSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLL 273
H T++ + L++A+ + LL +GA + G TPLH+A+ G +D + LLL
Sbjct: 623 HATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLL 682
Query: 274 QHGASIHDRDAKGETPISIA 293
GA+IH G T + +A
Sbjct: 683 DKGANIHMSTKSGLTSLHLA 702
Score = 48.1 bits (113), Expect = 1e-05
Identities = 25/86 (29%), Positives = 44/86 (51%)
Query: 214 HWTSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLL 273
H +++ +L++A+ + L +HGA + + LG TPL VA G + LL
Sbjct: 689 HMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLL 748
Query: 274 QHGASIHDRDAKGETPISIAHRLNHT 299
+ GA+++ + G TP+ A + HT
Sbjct: 749 KQGANVNAKTKNGYTPLHQAAQQGHT 774
Score = 45.1 bits (105), Expect = 1e-04
Identities = 25/77 (32%), Positives = 40/77 (51%)
Query: 217 SQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHG 276
+++ L++AS GH D V LL+ GA+ + G T LH+AA + + +L +HG
Sbjct: 659 TKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHG 718
Query: 277 ASIHDRDAKGETPISIA 293
A G TP+ +A
Sbjct: 719 ADQDAHTKLGYTPLIVA 735
Score = 37.7 bits (86), Expect = 0.015
Identities = 26/74 (35%), Positives = 38/74 (51%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L++A+ H + V++LL+H A + T LHVAA G LLL A+ + R
Sbjct: 336 LHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARA 395
Query: 284 AKGETPISIAHRLN 297
G TP+ IA + N
Sbjct: 396 LNGFTPLHIACKKN 409
>gi|62988328 ankyrin repeat domain 50 [Homo sapiens]
Length = 1429
Score = 60.5 bits (145), Expect = 2e-09
Identities = 43/126 (34%), Positives = 59/126 (46%), Gaps = 17/126 (13%)
Query: 169 HHD--GWTELVLAAVEGDPSKLSCLGLTEDSFYRTANSEHFEGEKWKHWTSQRAFVALYV 226
H D GWT L +AA EG +L C L E A + + + + +
Sbjct: 842 HRDDAGWTPLHMAAFEGH--RLICEALIEQG----ARTNEIDND---------GRIPFIL 886
Query: 227 ASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRDAKG 286
AS GH+D VQ LLE+ ++ R GR L VAA G D + LL HGA ++ +DA G
Sbjct: 887 ASQEGHYDCVQILLENKSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADG 946
Query: 287 ETPISI 292
+ I
Sbjct: 947 RPTLYI 952
Score = 55.8 bits (133), Expect = 5e-08
Identities = 45/125 (36%), Positives = 61/125 (48%), Gaps = 14/125 (11%)
Query: 171 DGWTELVLAAVEGDPSK--LSCLGLTEDSFYRTANSEHFEGEKWKHWTSQRAFVALYVAS 228
DG T L +AA+ SK S + L D R A +H + + L VA+
Sbjct: 709 DGRTALSVAALCVPASKGHASVVSLLID---RGAEVDHCDKD---------GMTPLLVAA 756
Query: 229 HRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRDAKGET 288
+ GH D V LLE GA GRTPL AA+MG + + LL GA++ D++G T
Sbjct: 757 YEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRT 816
Query: 289 PISIA 293
+SIA
Sbjct: 817 VLSIA 821
Score = 55.5 bits (132), Expect = 7e-08
Identities = 41/123 (33%), Positives = 54/123 (43%), Gaps = 15/123 (12%)
Query: 171 DGWTELVLAAVEGDPSKLSCLGLTEDSFYRTANSEHFEGEKWKHWTSQRAFVALYVASHR 230
DGWT L AA G +S L Y + + + + AL A+
Sbjct: 610 DGWTALRSAAWGGHTEVVSAL------LYAGVKVDCADAD---------SRTALRAAAWG 654
Query: 231 GHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRDAKGETPI 290
GH D V LL+HGA GRT L AA MG + + LL HGA ++ D G T +
Sbjct: 655 GHEDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTAL 714
Query: 291 SIA 293
S+A
Sbjct: 715 SVA 717
Score = 52.8 bits (125), Expect = 5e-07
Identities = 29/63 (46%), Positives = 35/63 (55%)
Query: 216 TSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQH 275
T + AL +A+ GH D VQ LLEHGA GRT + VAA G S I LL ++
Sbjct: 1041 TCNQGATALCIAAQEGHIDVVQVLLEHGADPNHADQFGRTAMRVAAKNGHSQIIKLLEKY 1100
Query: 276 GAS 278
GAS
Sbjct: 1101 GAS 1103
Score = 52.4 bits (124), Expect = 6e-07
Identities = 40/127 (31%), Positives = 54/127 (42%), Gaps = 15/127 (11%)
Query: 172 GWTELVLAAVEGDPSKLSCLGLTEDSFYRTANSEHFEGEKWKHWTSQRAFVALYVASHRG 231
G T L LAA +G ++CL AN H + + W AL A+ G
Sbjct: 578 GHTPLTLAARQGHTKVVNCL------IGCGANINHTDQDGW---------TALRSAAWGG 622
Query: 232 HFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRDAKGETPIS 291
H + V LL G RT L AA G D ++ LLQHGA ++ D +G T +
Sbjct: 623 HTEVVSALLYAGVKVDCADADSRTALRAAAWGGHEDIVLNLLQHGAEVNKADNEGRTALI 682
Query: 292 IAHRLNH 298
A + H
Sbjct: 683 AAAYMGH 689
Score = 51.6 bits (122), Expect = 1e-06
Identities = 35/98 (35%), Positives = 50/98 (51%), Gaps = 6/98 (6%)
Query: 223 ALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDR 282
AL A+ +GH VQ L+EHGA G T L +AA G D + +LL+HGA +
Sbjct: 1015 ALQSAAWQGHVKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVLLEHGADPNHA 1074
Query: 283 DAKGETPISIAHRLNHTLSERQMVLLHRIAKSGIRDLN 320
D G T + +A + H+ Q++ L + K G LN
Sbjct: 1075 DQFGRTAMRVAAKNGHS----QIIKL--LEKYGASSLN 1106
Score = 50.4 bits (119), Expect = 2e-06
Identities = 29/76 (38%), Positives = 38/76 (50%)
Query: 223 ALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDR 282
AL V + +GH V L++ GA G TPL VAA G D + LLL+ GA +
Sbjct: 718 ALCVPASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHT 777
Query: 283 DAKGETPISIAHRLNH 298
D G TP+ A + H
Sbjct: 778 DNNGRTPLLAAASMGH 793
Score = 49.7 bits (117), Expect = 4e-06
Identities = 29/81 (35%), Positives = 42/81 (51%), Gaps = 5/81 (6%)
Query: 223 ALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVA-----AAMGRSDCIILLLQHGA 277
AL A++ GH + V++LL+HGA GRT L VA A+ G + + LL+ GA
Sbjct: 680 ALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHASVVSLLIDRGA 739
Query: 278 SIHDRDAKGETPISIAHRLNH 298
+ D G TP+ +A H
Sbjct: 740 EVDHCDKDGMTPLLVAAYEGH 760
Score = 49.3 bits (116), Expect = 5e-06
Identities = 27/66 (40%), Positives = 38/66 (57%)
Query: 234 DAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRDAKGETPISIA 293
D+++ LL++GAS GRT L AA G D + LL+ GA + DA G TP+++A
Sbjct: 526 DSIRTLLDNGASVNQCDSNGRTLLANAAYSGSLDVVNLLVSRGADLEIEDAHGHTPLTLA 585
Query: 294 HRLNHT 299
R HT
Sbjct: 586 ARQGHT 591
Score = 48.1 bits (113), Expect = 1e-05
Identities = 40/130 (30%), Positives = 52/130 (40%), Gaps = 15/130 (11%)
Query: 171 DGWTELVLAAVEGDPSKLSCLGLTEDSFYRTANSEHFEGEKWKHWTSQRAFVALYVASHR 230
DG T L++AA EG + L EG T L A+
Sbjct: 747 DGMTPLLVAAYEGHVDVVDLL---------------LEGGADVDHTDNNGRTPLLAAASM 791
Query: 231 GHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRDAKGETPI 290
GH V LL GA+ S GRT L +A+A G + + LL G + RD G TP+
Sbjct: 792 GHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPL 851
Query: 291 SIAHRLNHTL 300
+A H L
Sbjct: 852 HMAAFEGHRL 861
Score = 43.1 bits (100), Expect = 4e-04
Identities = 25/75 (33%), Positives = 38/75 (50%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L +AS +G+ + V+ LL+ G R G TPLH+AA G L++ GA ++ D
Sbjct: 818 LSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEID 877
Query: 284 AKGETPISIAHRLNH 298
G P +A + H
Sbjct: 878 NDGRIPFILASQEGH 892
Score = 39.3 bits (90), Expect = 0.005
Identities = 24/73 (32%), Positives = 34/73 (46%)
Query: 227 ASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRDAKG 286
A++ G D V L+ GA G TPL +AA G + + L+ GA+I+ D G
Sbjct: 552 AAYSGSLDVVNLLVSRGADLEIEDAHGHTPLTLAARQGHTKVVNCLIGCGANINHTDQDG 611
Query: 287 ETPISIAHRLNHT 299
T + A HT
Sbjct: 612 WTALRSAAWGGHT 624
Score = 37.4 bits (85), Expect = 0.020
Identities = 19/75 (25%), Positives = 36/75 (48%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
LY+ + +Y LE+GA+ + GRT LHV+ G + + +L+ + A ++ D
Sbjct: 950 LYILALENQLTMAEYFLENGANVEASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAAD 1009
Query: 284 AKGETPISIAHRLNH 298
+ + + A H
Sbjct: 1010 NEKRSALQSAAWQGH 1024
Score = 31.6 bits (70), Expect = 1.1
Identities = 21/60 (35%), Positives = 32/60 (53%), Gaps = 2/60 (3%)
Query: 234 DAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRDAKGETPISIA 293
+ +Q L++ GA S RT V A+ R D I LL +GAS++ D+ G T ++ A
Sbjct: 495 EVLQLLVKAGAHVNSEDD--RTSCIVRQALEREDSIRTLLDNGASVNQCDSNGRTLLANA 552
>gi|32967601 ankyrin 3 isoform 1 [Homo sapiens]
Length = 4377
Score = 60.1 bits (144), Expect = 3e-09
Identities = 29/83 (34%), Positives = 51/83 (61%)
Query: 216 TSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQH 275
T+ R AL++A+ G + V+YL++ GA +++ +TPLH++A +G++D + LLQ
Sbjct: 462 TNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQ 521
Query: 276 GASIHDRDAKGETPISIAHRLNH 298
GAS + G TP+ ++ R H
Sbjct: 522 GASPNAATTSGYTPLHLSAREGH 544
Score = 60.1 bits (144), Expect = 3e-09
Identities = 39/115 (33%), Positives = 60/115 (52%), Gaps = 10/115 (8%)
Query: 221 FVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIH 280
+ L++++ GH D +LL+HGAS + G TPLHVAA G+ + LLLQ AS
Sbjct: 533 YTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSAS-- 590
Query: 281 DRDAKGETPISIAHRLNHTLSERQMVLL-------HRIAKSGIRDLNDLVMKNAL 328
DA G++ ++ H H +++ +LL H AK+G L+ KN +
Sbjct: 591 -PDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQM 644
Score = 58.9 bits (141), Expect = 6e-09
Identities = 39/122 (31%), Positives = 61/122 (50%), Gaps = 15/122 (12%)
Query: 223 ALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDR 282
AL+VA+H GH+ + LL+ A+ +++ G TPLH+A R + LLL+HGASI
Sbjct: 370 ALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAV 429
Query: 283 DAKGETPISIAHRLNH---------------TLSERQMVLLHRIAKSGIRDLNDLVMKNA 327
G TPI +A + H T + R LH A+SG ++ ++++
Sbjct: 430 TESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDG 489
Query: 328 LQ 329
Q
Sbjct: 490 AQ 491
Score = 58.2 bits (139), Expect = 1e-08
Identities = 30/86 (34%), Positives = 48/86 (55%)
Query: 221 FVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIH 280
F L++A + ++ LL+HGAS + + G TP+HVAA MG + + L+ HGAS +
Sbjct: 401 FTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPN 460
Query: 281 DRDAKGETPISIAHRLNHTLSERQMV 306
+ +GET + +A R R +V
Sbjct: 461 TTNVRGETALHMAARSGQAEVVRYLV 486
Score = 57.8 bits (138), Expect = 1e-08
Identities = 29/82 (35%), Positives = 46/82 (56%)
Query: 217 SQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHG 276
++ + L+V H G+ V +LL+H A +++ G TPLH AA G + I +LLQ+
Sbjct: 727 TKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNN 786
Query: 277 ASIHDRDAKGETPISIAHRLNH 298
AS ++ G T + IA RL +
Sbjct: 787 ASPNELTVNGNTALGIARRLGY 808
Score = 56.2 bits (134), Expect = 4e-08
Identities = 29/70 (41%), Positives = 41/70 (58%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L++++ G D VQ LL+ GAS + + G TPLH++A G D LL HGAS+
Sbjct: 503 LHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITT 562
Query: 284 AKGETPISIA 293
KG TP+ +A
Sbjct: 563 KKGFTPLHVA 572
Score = 54.7 bits (130), Expect = 1e-07
Identities = 26/82 (31%), Positives = 50/82 (60%)
Query: 217 SQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHG 276
+Q AL++AS GH + V LL+ A+ + + G T LH+A+ G+++ + +L+ +G
Sbjct: 71 NQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNG 130
Query: 277 ASIHDRDAKGETPISIAHRLNH 298
A+++ + G TP+ +A + NH
Sbjct: 131 ANVNAQSQNGFTPLYMAAQENH 152
Score = 53.9 bits (128), Expect = 2e-07
Identities = 26/80 (32%), Positives = 46/80 (57%)
Query: 217 SQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHG 276
++ ++VA+ GH + V L+ HGAS + + G T LH+AA G+++ + L+Q G
Sbjct: 430 TESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDG 489
Query: 277 ASIHDRDAKGETPISIAHRL 296
A + + +TP+ I+ RL
Sbjct: 490 AQVEAKAKDDQTPLHISARL 509
Score = 53.9 bits (128), Expect = 2e-07
Identities = 31/82 (37%), Positives = 42/82 (51%)
Query: 216 TSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQH 275
T+++ F L+VA+ G + LL+ AS + G TPLHVAA +LLL
Sbjct: 561 TTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQ 620
Query: 276 GASIHDRDAKGETPISIAHRLN 297
GAS H G TP+ IA + N
Sbjct: 621 GASPHAAAKNGYTPLHIAAKKN 642
Score = 52.8 bits (125), Expect = 5e-07
Identities = 31/97 (31%), Positives = 54/97 (55%), Gaps = 1/97 (1%)
Query: 215 WTSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQ 274
+T++ L+VAS RG+ + V+ LL+ GA +++ G TPLH A G + +LL
Sbjct: 263 FTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLD 322
Query: 275 HGASIHDRDAKGETPISIAHRLNHTLSERQMVLLHRI 311
A I + G +P+ +A + +H L+ Q++L H +
Sbjct: 323 RAAPILSKTKNGLSPLHMATQGDH-LNCVQLLLQHNV 358
Score = 48.1 bits (113), Expect = 1e-05
Identities = 41/144 (28%), Positives = 71/144 (49%), Gaps = 18/144 (12%)
Query: 156 DVVPGGI-ISLCIWHHDGWTELVLAAVEGDPSKLSCLGLTEDSFYRTANSEHFEGEKWKH 214
D + G+ I++C + +G L LA+ EG +S L R AN +
Sbjct: 59 DYIKNGVDINIC--NQNGLNALHLASKEGHVEVVSEL------LQREANVDA-------- 102
Query: 215 WTSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQ 274
+++ AL++AS G + V+ L+ +GA+ ++S G TPL++AA + + LL
Sbjct: 103 -ATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLD 161
Query: 275 HGASIHDRDAKGETPISIAHRLNH 298
+GAS G TP+++A + H
Sbjct: 162 NGASQSLATEDGFTPLAVALQQGH 185
Score = 47.8 bits (112), Expect = 1e-05
Identities = 30/97 (30%), Positives = 46/97 (47%), Gaps = 2/97 (2%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L+ + GH V+ LL+ A LS++ G +PLH+A +C+ LLLQH + D
Sbjct: 305 LHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVT 364
Query: 284 AKGETPISIAHRLNHTLSERQMVLLHRIAKSGIRDLN 320
T + +A H + VLL + A + LN
Sbjct: 365 NDYLTALHVAAHCGHYKVAK--VLLDKKANPNAKALN 399
Score = 47.8 bits (112), Expect = 1e-05
Identities = 23/84 (27%), Positives = 42/84 (50%)
Query: 216 TSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQH 275
+++ L++A+ + + L+ GA +++ +G TPLHV G + LLQH
Sbjct: 693 SNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQH 752
Query: 276 GASIHDRDAKGETPISIAHRLNHT 299
A ++ + G TP+ A + HT
Sbjct: 753 SAKVNAKTKNGYTPLHQAAQQGHT 776
Score = 47.4 bits (111), Expect = 2e-05
Identities = 27/78 (34%), Positives = 40/78 (51%), Gaps = 7/78 (8%)
Query: 217 SQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHG 276
SQ F LY+A+ H + V++LL++GAS + G TPL VA G + LLL++
Sbjct: 137 SQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLEN- 195
Query: 277 ASIHDRDAKGETPISIAH 294
D KG+ + H
Sbjct: 196 ------DTKGKVRLPALH 207
Score = 45.4 bits (106), Expect = 7e-05
Identities = 23/80 (28%), Positives = 42/80 (52%)
Query: 214 HWTSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLL 273
H ++ + L++A+ + D LLE+GA + + G +H+AA G D + LLL
Sbjct: 625 HAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLL 684
Query: 274 QHGASIHDRDAKGETPISIA 293
A+++ + G TP+ +A
Sbjct: 685 GRNANVNLSNKSGLTPLHLA 704
Score = 43.5 bits (101), Expect = 3e-04
Identities = 22/76 (28%), Positives = 40/76 (52%)
Query: 217 SQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHG 276
+++ ++++A+ GH D V LL A+ + G TPLH+AA R + +L+ G
Sbjct: 661 TRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQG 720
Query: 277 ASIHDRDAKGETPISI 292
A + + G TP+ +
Sbjct: 721 AHVDAQTKMGYTPLHV 736
Score = 42.7 bits (99), Expect = 5e-04
Identities = 32/103 (31%), Positives = 51/103 (49%), Gaps = 8/103 (7%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L+VA+H + LL+ GAS + + G TPLH+AA + D LL++GA +
Sbjct: 602 LHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVT 661
Query: 284 AKGETPISIAHRLNHTLSERQMVLLHRIA------KSGIRDLN 320
+G + +A + H + +LL R A KSG+ L+
Sbjct: 662 RQGIASVHLAAQEGHV--DMVSLLLGRNANVNLSNKSGLTPLH 702
Score = 38.5 bits (88), Expect = 0.009
Identities = 27/91 (29%), Positives = 44/91 (48%), Gaps = 2/91 (2%)
Query: 223 ALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDR 282
AL++A+ + A LL++ + S G TPLH+AA G + LLL A++
Sbjct: 205 ALHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFT 264
Query: 283 DAKGETPISIAHRLNHTLSERQMVLLHRIAK 313
TP+ +A + + + +LL R AK
Sbjct: 265 ARNDITPLHVASKRGN--ANMVKLLLDRGAK 293
Score = 36.6 bits (83), Expect = 0.034
Identities = 26/86 (30%), Positives = 42/86 (48%), Gaps = 1/86 (1%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L++A+ H + VQ LL+H + T LHVAA G +LL A+ + +
Sbjct: 338 LHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKA 397
Query: 284 AKGETPISIAHRLNHTLSERQMVLLH 309
G TP+ IA + N + +++L H
Sbjct: 398 LNGFTPLHIACKKNR-IKVMELLLKH 422
Score = 31.6 bits (70), Expect = 1.1
Identities = 25/98 (25%), Positives = 41/98 (41%), Gaps = 7/98 (7%)
Query: 203 NSEHFEGEKWKHWTSQR-------AFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRT 255
N+E +K KH R A + A+ GH + +++G + G
Sbjct: 17 NAEEEPEKKRKHRKRSRDRKKKSDANASYLRAARAGHLEKALDYIKNGVDINICNQNGLN 76
Query: 256 PLHVAAAMGRSDCIILLLQHGASIHDRDAKGETPISIA 293
LH+A+ G + + LLQ A++ KG T + IA
Sbjct: 77 ALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIA 114
>gi|92087060 ankyrin repeat and SOCS box-containing 15 [Homo
sapiens]
Length = 588
Score = 59.7 bits (143), Expect = 4e-09
Identities = 34/104 (32%), Positives = 50/104 (48%), Gaps = 5/104 (4%)
Query: 212 WKHWTSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIIL 271
W + + + L +A +G +D V L++H S + +H AA GR D + L
Sbjct: 136 WPNTKNDKGETPLLIAVKKGSYDMVSTLIKHNTSLDQPCVKRWSAMHEAAKQGRKDIVAL 195
Query: 272 LLQHGASIHDRDAKGETPISIAHRLNHTLSERQMVLLHRIAKSG 315
LL+HG ++H RD G TP+ +A H VL H I K G
Sbjct: 196 LLKHGGNVHLRDGFGVTPLGVAAEYGHC-----DVLEHLIHKGG 234
Score = 49.7 bits (117), Expect = 4e-06
Identities = 32/100 (32%), Positives = 53/100 (53%), Gaps = 3/100 (3%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L VA+ GH D +++L+ G L+ + G + L AA G DCI LLL++G S + +
Sbjct: 214 LGVAAEYGHCDVLEHLIHKGGDVLALADDGASVLFEAAGGGNPDCISLLLEYGGSGNVPN 273
Query: 284 AKGETPISIAHRLNHTLSERQMVLL---HRIAKSGIRDLN 320
G PI A H L+ + ++ + + I KSG+ ++
Sbjct: 274 RAGHLPIHRAAYEGHYLALKYLIPVTSKNAIRKSGLTPIH 313
Score = 35.8 bits (81), Expect = 0.058
Identities = 26/89 (29%), Positives = 43/89 (48%), Gaps = 15/89 (16%)
Query: 253 GRTPLHVAAAMGRSDCIILLLQHGASIHDRDAKGETPISIAHR----------LNHTLSE 302
G TPL +A G + + LL+ G + ++ KGETP+ IA + + H S
Sbjct: 111 GETPLTLAVKAGLVENVRTLLEKGVWPNTKNDKGETPLLIAVKKGSYDMVSTLIKHNTSL 170
Query: 303 RQMVL-----LHRIAKSGIRDLNDLVMKN 326
Q + +H AK G +D+ L++K+
Sbjct: 171 DQPCVKRWSAMHEAAKQGRKDIVALLLKH 199
Score = 33.9 bits (76), Expect = 0.22
Identities = 17/57 (29%), Positives = 34/57 (59%), Gaps = 1/57 (1%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIH 280
++ A++ GH+ A++YL+ + R G TP+H AA + C+ LL+++G ++
Sbjct: 280 IHRAAYEGHYLALKYLIPVTSKNAIRKS-GLTPIHSAADGQNAQCLELLIENGFDVN 335
>gi|68131557 ankyrin repeat domain 28 [Homo sapiens]
Length = 1053
Score = 58.5 bits (140), Expect = 8e-09
Identities = 29/68 (42%), Positives = 38/68 (55%)
Query: 231 GHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRDAKGETPI 290
GH D V LL GA+ ++ GRT LH A G +C+ LLQHGA RD++G TPI
Sbjct: 664 GHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPI 723
Query: 291 SIAHRLNH 298
++ H
Sbjct: 724 HLSAACGH 731
Score = 55.1 bits (131), Expect = 9e-08
Identities = 34/95 (35%), Positives = 49/95 (51%), Gaps = 1/95 (1%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L+ A+ G+ + + LL GA + GR+PLH AAA C+ L+ GAS++D D
Sbjct: 409 LHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLD 468
Query: 284 AKGETPISIAHRLNHTLSERQMVLLHRIAKSGIRD 318
+G TP+ A + T + LL A GIRD
Sbjct: 469 ERGCTPLHYA-ATSDTDGKCLEYLLRNDANPGIRD 502
Score = 52.0 bits (123), Expect = 8e-07
Identities = 24/71 (33%), Positives = 40/71 (56%)
Query: 223 ALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDR 282
A++ A++ GH + V+ L+ HGA + TPLH AA+ G + LL G +++
Sbjct: 176 AIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEP 235
Query: 283 DAKGETPISIA 293
+A G TP+ +A
Sbjct: 236 NAYGNTPLHVA 246
Score = 52.0 bits (123), Expect = 8e-07
Identities = 27/65 (41%), Positives = 37/65 (56%)
Query: 223 ALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDR 282
AL+ + GH + V LL+HGA CL R GRTP+H++AA G + LLQ AS+
Sbjct: 689 ALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSAASMDAN 748
Query: 283 DAKGE 287
A +
Sbjct: 749 PATAD 753
Score = 49.3 bits (116), Expect = 5e-06
Identities = 25/81 (30%), Positives = 42/81 (51%)
Query: 218 QRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGA 277
++++ L+ A+ G V+YLL+ G + G TPLHVA G+ + L+ GA
Sbjct: 204 KKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGA 263
Query: 278 SIHDRDAKGETPISIAHRLNH 298
++ ++ KG TP+ A H
Sbjct: 264 IVNQKNEKGFTPLHFAAASTH 284
Score = 48.5 bits (114), Expect = 9e-06
Identities = 31/93 (33%), Positives = 49/93 (52%), Gaps = 2/93 (2%)
Query: 216 TSQRAFVALYVASHRGHFDAVQYLLEH-GASCLSRSPL-GRTPLHVAAAMGRSDCIILLL 273
T AF L+ A + A + L++ GAS ++ + GRTPLH AA +C+ LLL
Sbjct: 784 TEGNAFSPLHCAVINDNEGAAEMLIDTLGASIVNATDSKGRTPLHAAAFTDHVECLQLLL 843
Query: 274 QHGASIHDRDAKGETPISIAHRLNHTLSERQMV 306
H A ++ D+ G+TP+ +A T + +V
Sbjct: 844 SHNAQVNSVDSTGKTPLMMAAENGQTNTVEMLV 876
Score = 48.1 bits (113), Expect = 1e-05
Identities = 29/85 (34%), Positives = 44/85 (51%), Gaps = 1/85 (1%)
Query: 217 SQRAFVALYVASHRGHFD-AVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQH 275
+++ F L+ A+ H ++ L+ +GA +S G+TPLH+ A GR ++Q
Sbjct: 269 NEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQS 328
Query: 276 GASIHDRDAKGETPISIAHRLNHTL 300
GA I D G TP+ IA R H L
Sbjct: 329 GAVIDCEDKNGNTPLHIAARYGHEL 353
Score = 47.8 bits (112), Expect = 1e-05
Identities = 26/71 (36%), Positives = 39/71 (54%)
Query: 223 ALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDR 282
AL+ A+ GH + V+ LL GA+ + R +H AA MG + + LL+ HGA + +
Sbjct: 143 ALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCK 202
Query: 283 DAKGETPISIA 293
D K TP+ A
Sbjct: 203 DKKSYTPLHAA 213
Score = 46.6 bits (109), Expect = 3e-05
Identities = 26/70 (37%), Positives = 37/70 (52%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L++A+ G D + LL G + GRT LH AAA G +C+ LLL GA + +D
Sbjct: 376 LHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKD 435
Query: 284 AKGETPISIA 293
G +P+ A
Sbjct: 436 KFGRSPLHYA 445
Score = 46.6 bits (109), Expect = 3e-05
Identities = 28/84 (33%), Positives = 46/84 (54%), Gaps = 1/84 (1%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L++A++ GH A++ L++ R+ GRTPL +AA G +C+ +L+ GASI +D
Sbjct: 554 LHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILVKD 613
Query: 284 -AKGETPISIAHRLNHTLSERQMV 306
TPI A H+ R ++
Sbjct: 614 YILKRTPIHAAATNGHSECLRLLI 637
Score = 44.7 bits (104), Expect = 1e-04
Identities = 30/118 (25%), Positives = 52/118 (44%), Gaps = 15/118 (12%)
Query: 176 LVLAAVEGDPSKLSCLGLTEDSFYRTANSEHFEGEKWKHWTSQRAFVALYVASHRGHFDA 235
LV A GDP ++ L ++ N + L+ A++ G +
Sbjct: 12 LVQAIFNGDPDEVRALIFKKEDVNFQDNEKR---------------TPLHAAAYLGDAEI 56
Query: 236 VQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRDAKGETPISIA 293
++ L+ GA ++ TPLH A A + + +LL+H A ++ RD +TP+ IA
Sbjct: 57 IELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIA 114
Score = 42.7 bits (99), Expect = 5e-04
Identities = 26/70 (37%), Positives = 33/70 (47%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L++A+ GH + L+ GA R G PLH+AA G SDC LL G I D
Sbjct: 343 LHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPD 402
Query: 284 AKGETPISIA 293
G T + A
Sbjct: 403 DFGRTCLHAA 412
Score = 40.0 bits (92), Expect = 0.003
Identities = 27/114 (23%), Positives = 53/114 (46%), Gaps = 3/114 (2%)
Query: 216 TSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQH 275
T + L+ A+ H + +Q LL H A S G+TPL +AA G+++ + +L+
Sbjct: 819 TDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDSTGKTPLMMAAENGQTNTVEMLVSS 878
Query: 276 -GASIHDRDAKGETPISIAHRLNHTLSERQMVLLHRIAKSGIRDLNDLVMKNAL 328
A + +D T + +A H S +++L +I + + + ++ L
Sbjct: 879 ASAELTLQDNSKNTALHLACSKGHETS--ALLILEKITDRNLINATNAALQTPL 930
Score = 38.5 bits (88), Expect = 0.009
Identities = 29/88 (32%), Positives = 41/88 (46%), Gaps = 2/88 (2%)
Query: 234 DAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRDAKGETPISIA 293
+AVQ LL+H A +R +TPLH+AAA C L+ ++++ D G T + A
Sbjct: 88 EAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHA 147
Query: 294 HRLNHTLSERQMVLLHRIAKSGIRDLND 321
H E +LL R A D D
Sbjct: 148 AFSGH--GEMVKLLLSRGANINAFDKKD 173
Score = 38.5 bits (88), Expect = 0.009
Identities = 22/70 (31%), Positives = 32/70 (45%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L++ + G F Q +++ GA G TPLH+AA G I L+ GA R
Sbjct: 310 LHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRG 369
Query: 284 AKGETPISIA 293
G P+ +A
Sbjct: 370 IHGMFPLHLA 379
Score = 37.0 bits (84), Expect = 0.026
Identities = 36/132 (27%), Positives = 49/132 (37%), Gaps = 39/132 (29%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSP-LGRTPLHVAAAMGRS---------------- 266
L +A+ +GH + V L+ GAS L + L RTP+H AA G S
Sbjct: 587 LDLAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNGHSECLRLLIGNAEPQNAV 646
Query: 267 --------------------DCIILLLQHGASIHDRDAKGETPISIAHRLNHTLSERQMV 306
DC+ LL GA++ +D G T + H E
Sbjct: 647 DIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGH--EECVDA 704
Query: 307 LLHRIAKSGIRD 318
LL AK +RD
Sbjct: 705 LLQHGAKCLLRD 716
Score = 33.9 bits (76), Expect = 0.22
Identities = 19/46 (41%), Positives = 24/46 (52%)
Query: 253 GRTPLHVAAAMGRSDCIILLLQHGASIHDRDAKGETPISIAHRLNH 298
GRT LH AA G + + LLL GA+I+ D K I A + H
Sbjct: 140 GRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGH 185
Score = 32.7 bits (73), Expect = 0.49
Identities = 24/70 (34%), Positives = 35/70 (50%), Gaps = 3/70 (4%)
Query: 223 ALYVASHRGHFDAVQYLLEHGAS---CLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASI 279
AL++A +GH + +LE + + +TPLHVAA G + + LL GAS+
Sbjct: 893 ALHLACSKGHETSALLILEKITDRNLINATNAALQTPLHVAARNGLTMVVQELLGKGASV 952
Query: 280 HDRDAKGETP 289
D G TP
Sbjct: 953 LAVDENGYTP 962
Score = 30.4 bits (67), Expect = 2.4
Identities = 19/64 (29%), Positives = 34/64 (53%), Gaps = 2/64 (3%)
Query: 255 TPLHVAAAMGRSDCIILLLQHGASIHDRDAKGETPISIAHRLNHTLSERQMVLLHRIAKS 314
+PLH+AA G + +L+Q + R++ G TP+ +A H E VL+++ A
Sbjct: 552 SPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHV--ECVDVLINQGASI 609
Query: 315 GIRD 318
++D
Sbjct: 610 LVKD 613
>gi|169403959 ankyrin repeat domain 53 isoform a [Homo sapiens]
Length = 530
Score = 58.5 bits (140), Expect = 8e-09
Identities = 32/84 (38%), Positives = 46/84 (54%), Gaps = 4/84 (4%)
Query: 224 LYVASHRGH----FDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASI 279
L++ HR + + YLLE GA +++ G TPLH+AA G DC+ +L+Q GA++
Sbjct: 178 LHLVIHRDNTTVALPCIYYLLEKGADLNAQTCNGSTPLHLAARDGLLDCVKVLVQSGANV 237
Query: 280 HDRDAKGETPISIAHRLNHTLSER 303
H +DA G PI NH R
Sbjct: 238 HAQDAMGYKPIDFCKIWNHRACAR 261
>gi|169403957 ankyrin repeat domain 53 isoform b [Homo sapiens]
Length = 343
Score = 58.5 bits (140), Expect = 8e-09
Identities = 32/84 (38%), Positives = 46/84 (54%), Gaps = 4/84 (4%)
Query: 224 LYVASHRGH----FDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASI 279
L++ HR + + YLLE GA +++ G TPLH+AA G DC+ +L+Q GA++
Sbjct: 178 LHLVIHRDNTTVALPCIYYLLEKGADLNAQTCNGSTPLHLAARDGLLDCVKVLVQSGANV 237
Query: 280 HDRDAKGETPISIAHRLNHTLSER 303
H +DA G PI NH R
Sbjct: 238 HAQDAMGYKPIDFCKIWNHRACAR 261
>gi|55741641 kinase D-interacting substrate of 220 kDa [Homo
sapiens]
Length = 1771
Score = 57.4 bits (137), Expect = 2e-08
Identities = 41/128 (32%), Positives = 58/128 (45%), Gaps = 15/128 (11%)
Query: 171 DGWTELVLAAVEGDPSKLSCLGLTEDSFYRTANSEHFEGEKWKHWTSQRAFVALYVASHR 230
D WT L+ A+ EG + + E+ N EH + W AL A ++
Sbjct: 70 DNWTALISASKEGH------VHIVEELLKCGVNLEHRDMGGW---------TALMWACYK 114
Query: 231 GHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRDAKGETPI 290
G D V+ LL HGA+ P+ AA G +D + LLLQ+GA ++ D G TP+
Sbjct: 115 GRTDVVELLLSHGANPSVTGLYSVYPIIWAAGRGHADIVHLLLQNGAKVNCSDKYGTTPL 174
Query: 291 SIAHRLNH 298
A R H
Sbjct: 175 VWAARKGH 182
Score = 42.0 bits (97), Expect = 8e-04
Identities = 34/107 (31%), Positives = 49/107 (45%), Gaps = 15/107 (14%)
Query: 172 GWTELVLAAVEGDPSKLSCLGLTEDSFYRTANSEHFEGEKWKHWTSQRAFVALYVASHRG 231
G T L++AA +G+ L + ++ AN + + W AL AS G
Sbjct: 38 GQTPLMIAAEQGN------LEIVKELIKNGANCNLEDLDNW---------TALISASKEG 82
Query: 232 HFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGAS 278
H V+ LL+ G + R G T L A GR+D + LLL HGA+
Sbjct: 83 HVHIVEELLKCGVNLEHRDMGGWTALMWACYKGRTDVVELLLSHGAN 129
Score = 40.4 bits (93), Expect = 0.002
Identities = 26/73 (35%), Positives = 37/73 (50%)
Query: 223 ALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDR 282
ALY A +G+ V+ +L+ + G TPL A M + + LLL GA +
Sbjct: 305 ALYWAVEKGNATMVRDILQCNPDTEICTKDGETPLIKATKMRNIEVVELLLDKGAKVSAV 364
Query: 283 DAKGETPISIAHR 295
D KG+TP+ IA R
Sbjct: 365 DKKGDTPLHIAIR 377
Score = 37.4 bits (85), Expect = 0.020
Identities = 21/73 (28%), Positives = 35/73 (47%)
Query: 227 ASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRDAKG 286
A+ +GH + V++LL GA T L VA G + + +L+ +++ D G
Sbjct: 177 AARKGHLECVKHLLAMGADVDQEGANSMTALIVAVKGGYTQSVKEILKRNPNVNLTDKDG 236
Query: 287 ETPISIAHRLNHT 299
T + IA + HT
Sbjct: 237 NTALMIASKEGHT 249
Score = 32.3 bits (72), Expect = 0.64
Identities = 19/64 (29%), Positives = 33/64 (51%)
Query: 235 AVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRDAKGETPISIAH 294
A++ LLE R+ G+TPL +AA G + + L+++GA+ + D T + A
Sbjct: 20 ALKALLEKCKDVDERNECGQTPLMIAAEQGNLEIVKELIKNGANCNLEDLDNWTALISAS 79
Query: 295 RLNH 298
+ H
Sbjct: 80 KEGH 83
Score = 32.3 bits (72), Expect = 0.64
Identities = 27/98 (27%), Positives = 44/98 (44%), Gaps = 2/98 (2%)
Query: 220 AFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASI 279
+ AL VA G+ +V+ +L+ + G T L +A+ G ++ + LL G +
Sbjct: 203 SMTALIVAVKGGYTQSVKEILKRNPNVNLTDKDGNTALMIASKEGHTEIVQDLLDAGTYV 262
Query: 280 HDRDAKGETPISIAHRLNHTLSERQMVLLHRIAKSGIR 317
+ D G+T + A R H E LL + A IR
Sbjct: 263 NIPDRSGDTVLIGAVRGGHV--EIVRALLQKYADIDIR 298
Score = 30.8 bits (68), Expect = 1.9
Identities = 24/75 (32%), Positives = 32/75 (42%)
Query: 216 TSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQH 275
T + AL +AS GH + VQ LL+ G G T L A G + + LLQ
Sbjct: 232 TDKDGNTALMIASKEGHTEIVQDLLDAGTYVNIPDRSGDTVLIGAVRGGHVEIVRALLQK 291
Query: 276 GASIHDRDAKGETPI 290
A I R +T +
Sbjct: 292 YADIDIRGQDNKTAL 306
>gi|20270347 ankyrin repeat domain 54 [Homo sapiens]
Length = 300
Score = 56.6 bits (135), Expect = 3e-08
Identities = 33/80 (41%), Positives = 42/80 (52%)
Query: 223 ALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDR 282
AL+ AS G+ VQ LL+HGA R LG TPLH+AA I LL+ GA +
Sbjct: 146 ALHFASCNGNDQIVQLLLDHGADPNQRDGLGNTPLHLAACTNHVPVITTLLRGGARVDAL 205
Query: 283 DAKGETPISIAHRLNHTLSE 302
D G TP+ +A + L E
Sbjct: 206 DRAGRTPLHLAKSKLNILQE 225
Score = 54.3 bits (129), Expect = 2e-07
Identities = 28/65 (43%), Positives = 35/65 (53%)
Query: 234 DAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRDAKGETPISIA 293
+ VQ LLE GA + GRT LH A+ G + LLL HGA + RD G TP+ +A
Sbjct: 124 ETVQQLLEDGADPCAADDKGRTALHFASCNGNDQIVQLLLDHGADPNQRDGLGNTPLHLA 183
Query: 294 HRLNH 298
NH
Sbjct: 184 ACTNH 188
>gi|52486194 phospholipase A2, group VI isoform a [Homo sapiens]
Length = 806
Score = 56.2 bits (134), Expect = 4e-08
Identities = 32/95 (33%), Positives = 49/95 (51%)
Query: 216 TSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQH 275
TS AL+VA R FD LL HGA+ +R G TPLH+A + + I L+
Sbjct: 313 TSSAGNTALHVAVMRNRFDCAIVLLTHGANADARGEHGNTPLHLAMSKDNVEMIKALIVF 372
Query: 276 GASIHDRDAKGETPISIAHRLNHTLSERQMVLLHR 310
GA + + GETP +A ++ ++ + ++ L R
Sbjct: 373 GAEVDTPNDFGETPTFLASKIGRLVTRKAILTLLR 407
Score = 49.7 bits (117), Expect = 4e-06
Identities = 25/60 (41%), Positives = 33/60 (55%)
Query: 234 DAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRDAKGETPISIA 293
+ + LL+ G + S S G T LHVA R DC I+LL HGA+ R G TP+ +A
Sbjct: 298 EMARMLLKRGCNVNSTSSAGNTALHVAVMRNRFDCAIVLLTHGANADARGEHGNTPLHLA 357
Score = 30.8 bits (68), Expect = 1.9
Identities = 22/70 (31%), Positives = 37/70 (52%), Gaps = 4/70 (5%)
Query: 253 GRTPLHVAAAMGRSDCIILLLQHGASIHD-RDAKGETPISIAHRLNHTLSERQMVLLHRI 311
G TPLH+A G + ++ L+Q+ + D D KGET + H + + + LL R
Sbjct: 152 GCTPLHLACRKGDGEILVELVQYCHTQMDVTDYKGET---VFHYAVQGDNSQVLQLLGRN 208
Query: 312 AKSGIRDLND 321
A +G+ +N+
Sbjct: 209 AVAGLNQVNN 218
>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
Length = 2663
Score = 55.5 bits (132), Expect = 7e-08
Identities = 41/123 (33%), Positives = 63/123 (51%), Gaps = 15/123 (12%)
Query: 172 GWTELVLAAVEGDPSKLSCLGLTEDSFYRTANSEHFEGEKWKHWTSQRAFVALYVASHRG 231
G T L AA+ GD ++ L ++E + N + F G WT AL+ A +RG
Sbjct: 168 GETRLHRAAIRGDARRIKEL-ISEGA---DVNVKDFAG-----WT------ALHEACNRG 212
Query: 232 HFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRDAKGETPIS 291
++D + LL GA ++ TPLH AA G + LLL++G + + KGETP+
Sbjct: 213 YYDVAKQLLAAGAEVNTKGLDDDTPLHDAANNGHYKVVKLLLRYGGNPQQSNRKGETPLK 272
Query: 292 IAH 294
+A+
Sbjct: 273 VAN 275
Score = 34.3 bits (77), Expect = 0.17
Identities = 23/82 (28%), Positives = 36/82 (43%)
Query: 217 SQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHG 276
++R L+ A+ RG ++ L+ GA + G T LH A G D LL G
Sbjct: 165 NERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDVAKQLLAAG 224
Query: 277 ASIHDRDAKGETPISIAHRLNH 298
A ++ + +TP+ A H
Sbjct: 225 AEVNTKGLDDDTPLHDAANNGH 246
>gi|215598824 ankyrin repeat and SOCS box-containing 10 isoform 2
[Homo sapiens]
Length = 474
Score = 55.5 bits (132), Expect = 7e-08
Identities = 49/178 (27%), Positives = 79/178 (44%), Gaps = 28/178 (15%)
Query: 175 ELVLAAVEGDPSKL---SCLGLTEDSFYRTANSEHFEGEK--------WKHWTSQRAFVA 223
+ VLA G S++ S GL DS + T++ E + + W +
Sbjct: 105 QAVLAGDVGCVSRILADSSTGLAPDSVFDTSDPERWRDFRFNIRALRLWSLTYEEELTTP 164
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L+VA+ RGH + ++ LL A S +P GRT LH A A G + C+ +LL GA + D
Sbjct: 165 LHVAASRGHTEVLRLLLRRRARPDS-APGGRTALHEACAAGHTACVHVLLVAGADPNIAD 223
Query: 284 AKGETPISIAH----------------RLNHTLSERQMVLLHRIAKSGIRDLNDLVMK 325
G+ P+ + R++ E + LH A+ G +L DL+++
Sbjct: 224 QDGKRPLHLCRGPGTLECAELLLRFGARVDGRSEEEEETPLHVAARLGHVELADLLLR 281
Score = 40.8 bits (94), Expect = 0.002
Identities = 27/71 (38%), Positives = 37/71 (52%), Gaps = 1/71 (1%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGR-TPLHVAAAMGRSDCIILLLQHGASIHDR 282
L++ G + + LL GA RS TPLHVAA +G + LLL+ GA R
Sbjct: 230 LHLCRGPGTLECAELLLRFGARVDGRSEEEEETPLHVAARLGHVELADLLLRRGACPDAR 289
Query: 283 DAKGETPISIA 293
+A+G TP+ A
Sbjct: 290 NAEGWTPLLAA 300
Score = 37.0 bits (84), Expect = 0.026
Identities = 34/121 (28%), Positives = 52/121 (42%), Gaps = 23/121 (19%)
Query: 171 DGWTELVLAA-------VEGDPSKLSCLGLTEDSFYRTANSEHFEGEKWKHWTSQRAFVA 223
+GWT L+ A + + + CL L A+++ + +K +
Sbjct: 292 EGWTPLLAACDVRCQSITDAEATTARCLQLCSLLLSAGADADAADQDKQR---------P 342
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHV-----AAAMGRS--DCIILLLQHG 276
L++A RGH V+ LL G S + G TPLH AAA+ +S + LL HG
Sbjct: 343 LHLACRRGHAAVVELLLSCGVSANTMDYGGHTPLHCALQGPAAALAQSPEHVVRALLNHG 402
Query: 277 A 277
A
Sbjct: 403 A 403
Score = 32.3 bits (72), Expect = 0.64
Identities = 19/55 (34%), Positives = 26/55 (47%)
Query: 239 LLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRDAKGETPISIA 293
LL GA + + PLH+A G + + LLL G S + D G TP+ A
Sbjct: 325 LLSAGADADAADQDKQRPLHLACRRGHAAVVELLLSCGVSANTMDYGGHTPLHCA 379
>gi|215598819 ankyrin repeat and SOCS box-containing 10 isoform 1
[Homo sapiens]
Length = 512
Score = 55.5 bits (132), Expect = 7e-08
Identities = 49/178 (27%), Positives = 79/178 (44%), Gaps = 28/178 (15%)
Query: 175 ELVLAAVEGDPSKL---SCLGLTEDSFYRTANSEHFEGEK--------WKHWTSQRAFVA 223
+ VLA G S++ S GL DS + T++ E + + W +
Sbjct: 105 QAVLAGDVGCVSRILADSSTGLAPDSVFDTSDPERWRDFRFNIRALRLWSLTYEEELTTP 164
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L+VA+ RGH + ++ LL A S +P GRT LH A A G + C+ +LL GA + D
Sbjct: 165 LHVAASRGHTEVLRLLLRRRARPDS-APGGRTALHEACAAGHTACVHVLLVAGADPNIAD 223
Query: 284 AKGETPISIAH----------------RLNHTLSERQMVLLHRIAKSGIRDLNDLVMK 325
G+ P+ + R++ E + LH A+ G +L DL+++
Sbjct: 224 QDGKRPLHLCRGPGTLECAELLLRFGARVDGRSEEEEETPLHVAARLGHVELADLLLR 281
Score = 40.8 bits (94), Expect = 0.002
Identities = 27/71 (38%), Positives = 37/71 (52%), Gaps = 1/71 (1%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGR-TPLHVAAAMGRSDCIILLLQHGASIHDR 282
L++ G + + LL GA RS TPLHVAA +G + LLL+ GA R
Sbjct: 230 LHLCRGPGTLECAELLLRFGARVDGRSEEEEETPLHVAARLGHVELADLLLRRGACPDAR 289
Query: 283 DAKGETPISIA 293
+A+G TP+ A
Sbjct: 290 NAEGWTPLLAA 300
Score = 37.0 bits (84), Expect = 0.026
Identities = 34/121 (28%), Positives = 52/121 (42%), Gaps = 23/121 (19%)
Query: 171 DGWTELVLAA-------VEGDPSKLSCLGLTEDSFYRTANSEHFEGEKWKHWTSQRAFVA 223
+GWT L+ A + + + CL L A+++ + +K +
Sbjct: 292 EGWTPLLAACDVRCQSITDAEATTARCLQLCSLLLSAGADADAADQDKQR---------P 342
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHV-----AAAMGRS--DCIILLLQHG 276
L++A RGH V+ LL G S + G TPLH AAA+ +S + LL HG
Sbjct: 343 LHLACRRGHAAVVELLLSCGVSANTMDYGGHTPLHCALQGPAAALAQSPEHVVRALLNHG 402
Query: 277 A 277
A
Sbjct: 403 A 403
Score = 32.3 bits (72), Expect = 0.64
Identities = 19/55 (34%), Positives = 26/55 (47%)
Query: 239 LLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRDAKGETPISIA 293
LL GA + + PLH+A G + + LLL G S + D G TP+ A
Sbjct: 325 LLSAGADADAADQDKQRPLHLACRRGHAAVVELLLSCGVSANTMDYGGHTPLHCA 379
>gi|8051593 GA binding protein transcription factor, beta subunit 1
isoform beta 1 [Homo sapiens]
Length = 395
Score = 55.5 bits (132), Expect = 7e-08
Identities = 27/75 (36%), Positives = 45/75 (60%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L++A+ GH+ + LL G S +R+ + RTPLH+AA+ G + + +LL+HGA ++ +D
Sbjct: 42 LHLAAQYGHYSTTEVLLRAGVSRDARTKVDRTPLHMAASEGHASIVEVLLKHGADVNAKD 101
Query: 284 AKGETPISIAHRLNH 298
T + A NH
Sbjct: 102 MLKMTALHWATEHNH 116
Score = 44.7 bits (104), Expect = 1e-04
Identities = 22/70 (31%), Positives = 38/70 (54%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L++A+ GH V+ LL+HGA ++ L T LH A + + LL+++GA +H +
Sbjct: 75 LHMAASEGHASIVEVLLKHGADVNAKDMLKMTALHWATEHNHQEVVELLIKYGADVHTQS 134
Query: 284 AKGETPISIA 293
+T I+
Sbjct: 135 KFCKTAFDIS 144
Score = 36.6 bits (83), Expect = 0.034
Identities = 25/75 (33%), Positives = 36/75 (48%), Gaps = 1/75 (1%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L A+ G D V+ L+ +GA + LG +PLH+AA G +LL+ G S R
Sbjct: 10 LLEAARAGQDDEVRILMANGAP-FTTDWLGTSPLHLAAQYGHYSTTEVLLRAGVSRDART 68
Query: 284 AKGETPISIAHRLNH 298
TP+ +A H
Sbjct: 69 KVDRTPLHMAASEGH 83
>gi|8051595 GA binding protein transcription factor, beta subunit 1
isoform beta 2 [Homo sapiens]
Length = 383
Score = 55.5 bits (132), Expect = 7e-08
Identities = 27/75 (36%), Positives = 45/75 (60%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L++A+ GH+ + LL G S +R+ + RTPLH+AA+ G + + +LL+HGA ++ +D
Sbjct: 42 LHLAAQYGHYSTTEVLLRAGVSRDARTKVDRTPLHMAASEGHASIVEVLLKHGADVNAKD 101
Query: 284 AKGETPISIAHRLNH 298
T + A NH
Sbjct: 102 MLKMTALHWATEHNH 116
Score = 44.7 bits (104), Expect = 1e-04
Identities = 22/70 (31%), Positives = 38/70 (54%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L++A+ GH V+ LL+HGA ++ L T LH A + + LL+++GA +H +
Sbjct: 75 LHMAASEGHASIVEVLLKHGADVNAKDMLKMTALHWATEHNHQEVVELLIKYGADVHTQS 134
Query: 284 AKGETPISIA 293
+T I+
Sbjct: 135 KFCKTAFDIS 144
Score = 36.6 bits (83), Expect = 0.034
Identities = 25/75 (33%), Positives = 36/75 (48%), Gaps = 1/75 (1%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L A+ G D V+ L+ +GA + LG +PLH+AA G +LL+ G S R
Sbjct: 10 LLEAARAGQDDEVRILMANGAP-FTTDWLGTSPLHLAAQYGHYSTTEVLLRAGVSRDART 68
Query: 284 AKGETPISIAHRLNH 298
TP+ +A H
Sbjct: 69 KVDRTPLHMAASEGH 83
>gi|32483404 GA binding protein transcription factor, beta subunit 1
isoform gamma 2 [Homo sapiens]
Length = 348
Score = 55.5 bits (132), Expect = 7e-08
Identities = 27/75 (36%), Positives = 45/75 (60%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L++A+ GH+ + LL G S +R+ + RTPLH+AA+ G + + +LL+HGA ++ +D
Sbjct: 42 LHLAAQYGHYSTTEVLLRAGVSRDARTKVDRTPLHMAASEGHASIVEVLLKHGADVNAKD 101
Query: 284 AKGETPISIAHRLNH 298
T + A NH
Sbjct: 102 MLKMTALHWATEHNH 116
Score = 44.7 bits (104), Expect = 1e-04
Identities = 22/70 (31%), Positives = 38/70 (54%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L++A+ GH V+ LL+HGA ++ L T LH A + + LL+++GA +H +
Sbjct: 75 LHMAASEGHASIVEVLLKHGADVNAKDMLKMTALHWATEHNHQEVVELLIKYGADVHTQS 134
Query: 284 AKGETPISIA 293
+T I+
Sbjct: 135 KFCKTAFDIS 144
Score = 36.6 bits (83), Expect = 0.034
Identities = 25/75 (33%), Positives = 36/75 (48%), Gaps = 1/75 (1%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L A+ G D V+ L+ +GA + LG +PLH+AA G +LL+ G S R
Sbjct: 10 LLEAARAGQDDEVRILMANGAP-FTTDWLGTSPLHLAAQYGHYSTTEVLLRAGVSRDART 68
Query: 284 AKGETPISIAHRLNH 298
TP+ +A H
Sbjct: 69 KVDRTPLHMAASEGH 83
>gi|8051597 GA binding protein transcription factor, beta subunit 1
isoform gamma 1 [Homo sapiens]
Length = 360
Score = 55.5 bits (132), Expect = 7e-08
Identities = 27/75 (36%), Positives = 45/75 (60%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L++A+ GH+ + LL G S +R+ + RTPLH+AA+ G + + +LL+HGA ++ +D
Sbjct: 42 LHLAAQYGHYSTTEVLLRAGVSRDARTKVDRTPLHMAASEGHASIVEVLLKHGADVNAKD 101
Query: 284 AKGETPISIAHRLNH 298
T + A NH
Sbjct: 102 MLKMTALHWATEHNH 116
Score = 44.7 bits (104), Expect = 1e-04
Identities = 22/70 (31%), Positives = 38/70 (54%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L++A+ GH V+ LL+HGA ++ L T LH A + + LL+++GA +H +
Sbjct: 75 LHMAASEGHASIVEVLLKHGADVNAKDMLKMTALHWATEHNHQEVVELLIKYGADVHTQS 134
Query: 284 AKGETPISIA 293
+T I+
Sbjct: 135 KFCKTAFDIS 144
Score = 36.6 bits (83), Expect = 0.034
Identities = 25/75 (33%), Positives = 36/75 (48%), Gaps = 1/75 (1%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L A+ G D V+ L+ +GA + LG +PLH+AA G +LL+ G S R
Sbjct: 10 LLEAARAGQDDEVRILMANGAP-FTTDWLGTSPLHLAAQYGHYSTTEVLLRAGVSRDART 68
Query: 284 AKGETPISIAHRLNH 298
TP+ +A H
Sbjct: 69 KVDRTPLHMAASEGH 83
>gi|8051599 GA binding protein transcription factor, beta subunit 1
isoform gamma 2 [Homo sapiens]
Length = 348
Score = 55.5 bits (132), Expect = 7e-08
Identities = 27/75 (36%), Positives = 45/75 (60%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L++A+ GH+ + LL G S +R+ + RTPLH+AA+ G + + +LL+HGA ++ +D
Sbjct: 42 LHLAAQYGHYSTTEVLLRAGVSRDARTKVDRTPLHMAASEGHASIVEVLLKHGADVNAKD 101
Query: 284 AKGETPISIAHRLNH 298
T + A NH
Sbjct: 102 MLKMTALHWATEHNH 116
Score = 44.7 bits (104), Expect = 1e-04
Identities = 22/70 (31%), Positives = 38/70 (54%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L++A+ GH V+ LL+HGA ++ L T LH A + + LL+++GA +H +
Sbjct: 75 LHMAASEGHASIVEVLLKHGADVNAKDMLKMTALHWATEHNHQEVVELLIKYGADVHTQS 134
Query: 284 AKGETPISIA 293
+T I+
Sbjct: 135 KFCKTAFDIS 144
Score = 36.6 bits (83), Expect = 0.034
Identities = 25/75 (33%), Positives = 36/75 (48%), Gaps = 1/75 (1%)
Query: 224 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRD 283
L A+ G D V+ L+ +GA + LG +PLH+AA G +LL+ G S R
Sbjct: 10 LLEAARAGQDDEVRILMANGAP-FTTDWLGTSPLHLAAQYGHYSTTEVLLRAGVSRDART 68
Query: 284 AKGETPISIAHRLNH 298
TP+ +A H
Sbjct: 69 KVDRTPLHMAASEGH 83
>gi|156142184 ankyrin repeat domain 39 [Homo sapiens]
Length = 183
Score = 55.5 bits (132), Expect = 7e-08
Identities = 35/98 (35%), Positives = 50/98 (51%), Gaps = 1/98 (1%)
Query: 221 FVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIH 280
+ AL+ AS GH+ Q+LLE GA C +++ G T LH A+ G ++ LLL HG++
Sbjct: 65 YTALHYASRNGHYAVCQFLLESGAKCDAQTHGGATALHRASYCGHTEIARLLLSHGSNPR 124
Query: 281 DRDAKGETPISIAHRLNHTLSERQMVLLHRIAKSGIRD 318
D G T + A H ++L H A IRD
Sbjct: 125 VVDDDGMTSLHKAAERGHG-DICSLLLQHSPALKAIRD 161
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.135 0.417
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,736,611
Number of Sequences: 37866
Number of extensions: 658260
Number of successful extensions: 5783
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 355
Number of HSP's successfully gapped in prelim test: 200
Number of HSP's that attempted gapping in prelim test: 3626
Number of HSP's gapped (non-prelim): 2033
length of query: 345
length of database: 18,247,518
effective HSP length: 103
effective length of query: 242
effective length of database: 14,347,320
effective search space: 3472051440
effective search space used: 3472051440
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.