BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|239745153 PREDICTED: similar to Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] (655 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 1305 0.0 gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 1301 0.0 gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 527 e-149 gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 526 e-149 gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 526 e-149 gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 513 e-145 gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 424 e-118 gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 419 e-117 gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 319 4e-87 gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 229 8e-60 gi|239752551 PREDICTED: hypothetical protein [Homo sapiens] 222 7e-58 gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo sap... 183 5e-46 gi|148746195 trichohyalin [Homo sapiens] 180 3e-45 gi|31317305 M-phase phosphoprotein 10 [Homo sapiens] 176 5e-44 gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo sap... 155 1e-37 gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C... 155 1e-37 gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo sapi... 154 2e-37 gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo sapi... 152 1e-36 gi|221219020 NYD-SP11 protein [Homo sapiens] 148 1e-35 gi|194097392 Golgi autoantigen, golgin subfamily a, 2 [Homo sapi... 143 4e-34 gi|169210281 PREDICTED: similar to M-phase phosphoprotein 10 (U3... 140 5e-33 gi|169210488 PREDICTED: similar to M-phase phosphoprotein 10 (U3... 140 5e-33 gi|169210051 PREDICTED: similar to M-phase phosphoprotein 10 (U3... 140 5e-33 gi|169208458 PREDICTED: similar to golgi autoantigen, golgin sub... 139 8e-33 gi|154937324 hypothetical protein LOC440295 [Homo sapiens] 139 8e-33 gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 134 3e-31 gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 134 3e-31 gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 134 3e-31 gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 134 3e-31 gi|239745259 PREDICTED: hypothetical protein isoform 2 [Homo sap... 133 6e-31 >gi|239745153 PREDICTED: similar to Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 655 Score = 1305 bits (3376), Expect = 0.0 Identities = 655/655 (100%), Positives = 655/655 (100%) Query: 1 MGGDNPEVSERANSSKFDPTKSPVLSDEDSDLDFHINKLEQQSKVRNKGHGKPREKSIAD 60 MGGDNPEVSERANSSKFDPTKSPVLSDEDSDLDFHINKLEQQSKVRNKGHGKPREKSIAD Sbjct: 1 MGGDNPEVSERANSSKFDPTKSPVLSDEDSDLDFHINKLEQQSKVRNKGHGKPREKSIAD 60 Query: 61 EKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAG 120 EKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAG Sbjct: 61 EKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAG 120 Query: 121 VSHVKKNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETL 180 VSHVKKNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETL Sbjct: 121 VSHVKKNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETL 180 Query: 181 HFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLN 240 HFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLN Sbjct: 181 HFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLN 240 Query: 241 VKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMW 300 VKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMW Sbjct: 241 VKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMW 300 Query: 301 RQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEE 360 RQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEE Sbjct: 301 RQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEE 360 Query: 361 KIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDE 420 KIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDE Sbjct: 361 KIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDE 420 Query: 421 KIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQE 480 KIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQE Sbjct: 421 KIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQE 480 Query: 481 QEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRL 540 QEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRL Sbjct: 481 QEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRL 540 Query: 541 WQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQ 600 WQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQ Sbjct: 541 WQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQ 600 Query: 601 SLQQQQDHYRGHLQQYVAAYQQLASGKEALPSCSSRKLRAKRWLRWPTNSCRRPS 655 SLQQQQDHYRGHLQQYVAAYQQLASGKEALPSCSSRKLRAKRWLRWPTNSCRRPS Sbjct: 601 SLQQQQDHYRGHLQQYVAAYQQLASGKEALPSCSSRKLRAKRWLRWPTNSCRRPS 655 >gi|239745127 PREDICTED: similar to Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 655 Score = 1301 bits (3366), Expect = 0.0 Identities = 654/655 (99%), Positives = 654/655 (99%) Query: 1 MGGDNPEVSERANSSKFDPTKSPVLSDEDSDLDFHINKLEQQSKVRNKGHGKPREKSIAD 60 MGGDNPEVSERANSSKFDPTKSPVLSDEDSDLDFHINKLEQQSKVRNKGHGKPREKSIAD Sbjct: 1 MGGDNPEVSERANSSKFDPTKSPVLSDEDSDLDFHINKLEQQSKVRNKGHGKPREKSIAD 60 Query: 61 EKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAG 120 EKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAG Sbjct: 61 EKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAG 120 Query: 121 VSHVKKNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETL 180 VSHVKKNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETL Sbjct: 121 VSHVKKNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETL 180 Query: 181 HFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLN 240 HFDHAVRMGTYIEKLTKERDA SLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLN Sbjct: 181 HFDHAVRMGTYIEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLN 240 Query: 241 VKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMW 300 VKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMW Sbjct: 241 VKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMW 300 Query: 301 RQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEE 360 RQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEE Sbjct: 301 RQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEE 360 Query: 361 KIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDE 420 KIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDE Sbjct: 361 KIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDE 420 Query: 421 KIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQE 480 KIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQE Sbjct: 421 KIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQE 480 Query: 481 QEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRL 540 QEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRL Sbjct: 481 QEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRL 540 Query: 541 WQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQ 600 WQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQ Sbjct: 541 WQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQ 600 Query: 601 SLQQQQDHYRGHLQQYVAAYQQLASGKEALPSCSSRKLRAKRWLRWPTNSCRRPS 655 SLQQQQDHYRGHLQQYVAAYQQLASGKEALPSCSSRKLRAKRWLRWPTNSCRRPS Sbjct: 601 SLQQQQDHYRGHLQQYVAAYQQLASGKEALPSCSSRKLRAKRWLRWPTNSCRRPS 655 >gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 668 Score = 527 bits (1357), Expect = e-149 Identities = 306/472 (64%), Positives = 341/472 (72%), Gaps = 102/472 (21%) Query: 191 YIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLER 250 YIE+LTKERDA SLELYRNTITDEELKEKNA+LQEKL+LVESEKSEIQLNVK+LKRKLER Sbjct: 194 YIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLER 253 Query: 251 AQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQE-- 308 A+LLLPQQQLQ EAD LGKELQSVSAKLQAQVEENELWN LNQQQEEKMWRQEEKIQE Sbjct: 254 AKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWE 313 Query: 309 -----QEEKMCEQELKIREQEEKMWRQEE------------------------------- 332 QEEK+ EQE KIREQEEKM RQEE Sbjct: 314 EKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMW 373 Query: 333 -----------KMHEQE------------EKIREQED------KMWRQEEKIREQEEKIR 363 KMHEQE EKIREQE KMWRQEEKIREQEEKIR Sbjct: 374 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 433 Query: 364 EQEEKMWRQEEKIREQDEKIQEQE-----EEMWRQEEKIREQEE---------------K 403 EQE+KMWRQEEKI EQ EKI+E+E EEMWRQEEKIREQEE K Sbjct: 434 EQEKKMWRQEEKIHEQ-EKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRK 492 Query: 404 RQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEK 463 ++EK+WRQE+KM +Q+EKIREQEE+MWRQEEKIRE EE +++QEEK+RE EE MQE+EEK Sbjct: 493 QEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEK 552 Query: 464 MQEQEEKIQ------RQEEKIQEQEEKTWRQ-EKLLKQEEKIWEQEEK-------MWRQE 509 M EQEEK+Q RQEEKI+EQEEK Q EK+ +QEEKIWEQEEK M QE Sbjct: 553 MGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQE 612 Query: 510 EKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERL 561 EKMWEQEEKM EQEEKMQ QEEKMR QE ++W+QE ++++QE ++QE +E L Sbjct: 613 EKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHL 664 Score = 342 bits (876), Expect = 8e-94 Identities = 219/512 (42%), Positives = 308/512 (60%), Gaps = 82/512 (16%) Query: 66 LSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVK 125 +++ E +N K + + E + E + K+ K L+R LP + +A H+ Sbjct: 214 ITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEA--DHLG 271 Query: 126 KNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQK--RPENSLLE-ETLHF 182 K E++S K Q ++ E W RL + +K R E + E E Sbjct: 272 K---ELQSVSAKLQAQVEENEL-----------WNRLNQQQEEKMWRQEEKIQEWEEKIQ 317 Query: 183 DHAVRMGTYIEKLTKERDAPSLELYRNTITDEELKEKNA---ELQEKLRLVESEKSEIQL 239 + ++ EK+ ++ + + +E+++ + E +EK+R +E E + Sbjct: 318 EQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEE 377 Query: 240 NVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKM 299 +++L+ K+ + + Q++ + E +++ ++ + Q+QE KM Sbjct: 378 KIRELEEKMHEQEKIREQEEKRQEEEKIREQEK-------------------RQEQEAKM 418 Query: 300 WRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQE----EKIREQEDKMWRQEEKI 355 WRQEEKI+EQEEK IREQE+KMWRQEEK+HEQE E+ R+++++MWRQEEKI Sbjct: 419 WRQEEKIREQEEK-------IREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKI 471 Query: 356 REQE------------EKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEK 403 REQE EKIR+QEEK+WRQEEK+ +Q+EKI+EQEE+MWRQEEKIREQEE Sbjct: 472 REQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEE- 530 Query: 404 RQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEK 463 K+REQ+EKIREQEE M QEEK+ E EE MQ+Q EK+R EEK++E+EEK Sbjct: 531 ----------KIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQ-EKMRRQEEKIREQEEK 579 Query: 464 MQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQE 523 ++EQ+EKI+ QEEKI EQEEK QE++++ EQEEKMW QEEKM EQEEKMQEQE Sbjct: 580 IREQKEKIREQEEKIWEQEEKIREQEEMMQ------EQEEKMWEQEEKMCEQEEKMQEQE 633 Query: 524 EKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQ 555 EKM+RQEEKM EQEVRL QQEEKMQE + L+ Sbjct: 634 EKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLE 665 Score = 196 bits (499), Expect = 4e-50 Identities = 144/466 (30%), Positives = 238/466 (51%), Gaps = 87/466 (18%) Query: 21 KSPVLSDEDSDLDFHINKLE-----------QQSKVRNKGHGKPREKSIADEKFFQLSEM 69 K ++ E S++ ++ +L+ QQ H +S++ + Q+ E Sbjct: 229 KLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEEN 288 Query: 70 EAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSD 129 E + +++ K W +++ ++E E+ Q +E R +E I Sbjct: 289 ELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIR-----EQEEKIR------------ 331 Query: 130 EVKSSFKKRQEKMNEKNYTFRKRVVI----KKPWLRLGEVTAQKRPENSLLEETLHFDHA 185 E + ++++E M EK R++ + ++ RL E+ +K + LEE +H Sbjct: 332 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEK 391 Query: 186 VR----MGTYIEKLTKE--RDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQL 239 +R EK+ ++ R +++R E +EK E QEK + EK Q Sbjct: 392 IREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE-QEKKMWRQEEKIHEQE 450 Query: 240 NVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQ------ 293 +++ +++ E+ ++ +++++ E + + ++ + + + + + +E ++W + Sbjct: 451 KIREEEKRQEQEEMWRQEEKIR-EQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEE 509 Query: 294 ---QQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEK---------- 340 +QEEKMWRQEEKI+EQEEK+ EQE KIREQEE M QEEKM EQEEK Sbjct: 510 KIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQ 569 Query: 341 -----------------IREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKI 383 IREQE+K+W QEEKIREQEE ++EQEEKMW QEEK+ EQ+EK+ Sbjct: 570 EEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKM 629 Query: 384 QEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEM 429 QEQEE+M RQE EKMW QE ++R+Q+EK++E +E + Sbjct: 630 QEQEEKMRRQE-----------EKMWEQEVRLRQQEEKMQEHQEHL 664 >gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sapiens] Length = 570 Score = 526 bits (1356), Expect = e-149 Identities = 288/388 (74%), Positives = 323/388 (83%), Gaps = 29/388 (7%) Query: 191 YIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLER 250 YIE+LTKERDA SLELYRNTITDEELKEKNA+LQEKL+LVESEKSEIQLNVK+LKRKLER Sbjct: 182 YIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLER 241 Query: 251 AQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQE 310 A+LLLPQQQLQ EAD LGKELQSVSAKLQAQVEENELWN LNQQQEEKMWRQEEKIQE+E Sbjct: 242 AKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQERE 301 Query: 311 EKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIRE------QEEKIRE 364 EK+ EQE KIREQEEKM RQEE M E+EEK+R QE+ MW +EEKIRE ++EKIRE Sbjct: 302 EKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIRE 361 Query: 365 QEE-------------------KMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEK-- 403 QEE KMWRQEEKIREQ+EKI+EQEE M QEEK+ EQEEK Sbjct: 362 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMW 421 Query: 404 -RQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462 ++E+M QE+KMR Q+EKIREQE+++ QEEKIRE EEMMQ+QEEK+ E E KM E+E Sbjct: 422 EQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEA 481 Query: 463 KMQEQEEKIQRQEEKIQEQEEKTWRQ-EKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQE 521 KMQEQEEK++RQEEKI+EQE+K Q EK+ +QEE + EQEEKMW QEEKM EQEEKMQE Sbjct: 482 KMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 541 Query: 522 QEEKMQRQEEKMREQEVRLWQQEEKMQE 549 QEEKM+RQEEKMREQEVRL QQEEKMQE Sbjct: 542 QEEKMRRQEEKMREQEVRLRQQEEKMQE 569 Score = 198 bits (504), Expect = 1e-50 Identities = 145/429 (33%), Positives = 222/429 (51%), Gaps = 87/429 (20%) Query: 21 KSPVLSDEDSDLDFHINKLE-----------QQSKVRNKGHGKPREKSIADEKFFQLSEM 69 K ++ E S++ ++ +L+ QQ H +S++ + Q+ E Sbjct: 217 KLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEEN 276 Query: 70 EAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSD 129 E + +++ K W +++ ++E E+ Q +E R Sbjct: 277 ELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIR------------------------ 312 Query: 130 EVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMG 189 E + ++++E M EK R++ E+ +K + LEE +H +R Sbjct: 313 EQEEKMRRQEEMMWEKEEKMRRQE----------EMMWEKEEKIRELEEKMHEQEKIR-- 360 Query: 190 TYIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLE 249 E+ K ++ + +EK E + K+ E + E + +++ Sbjct: 361 ---EQEEKRQEEEKIRE----------QEKRQEQEAKMWRQEEKIREQEEKIRE------ 401 Query: 250 RAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQ 309 ++ +Q + +++G++ K+ Q EE Q+QEEKM RQEEKI+EQ Sbjct: 402 ------QEEMMQEQEEKMGEQ----EEKMWEQEEE-------MQEQEEKMRRQEEKIREQ 444 Query: 310 EEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKM 369 E+K+ EQE KIREQEE M QEEKM EQE K+ EQE KM QEEK+R QEEKIREQE+K+ Sbjct: 445 EKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKI 504 Query: 370 WRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEM 429 QEEKIREQ+E +QEQEE+MW QEEK+ EQEEK QE QE+KMR Q+EK+REQE + Sbjct: 505 REQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE----QEEKMRRQEEKMREQEVRL 560 Query: 430 WRQEEKIRE 438 +QEEK++E Sbjct: 561 RQQEEKMQE 569 >gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 724 Score = 526 bits (1355), Expect = e-149 Identities = 303/467 (64%), Positives = 337/467 (72%), Gaps = 97/467 (20%) Query: 191 YIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLER 250 YIE+LTKERDA SLELYRNTITDEELKEKNA+LQEKL+LVESEKSEIQLNVK+LKRKLER Sbjct: 255 YIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLER 314 Query: 251 AQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQE-- 308 A+LLLPQQQLQ EAD LGKELQSVSAKLQAQVEENELWN LNQQQEEKMWRQEEKIQE Sbjct: 315 AKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWE 374 Query: 309 -----QEEKMCEQELKIREQEEKMWRQEE------------------------------- 332 QEEK+ EQE KIREQEEKM RQEE Sbjct: 375 EKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMW 434 Query: 333 -----------KMHEQE------------EKIREQED------KMWRQEEKIREQEEKIR 363 KMHEQE EKIREQE KMWRQEEKIREQEEKIR Sbjct: 435 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 494 Query: 364 EQEEKMWRQEEKIREQDEKIQEQE-----EEMWRQEEKIREQEE---------------- 402 EQEEKMWRQEEKI EQ EKI+E+E EEMWRQEEKIREQEE Sbjct: 495 EQEEKMWRQEEKIHEQ-EKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIR 553 Query: 403 KRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462 K++EKMWRQE+KM +Q+EKIREQEE++WRQEEKIRE EE +++QEEK+RE EE QE+EE Sbjct: 554 KQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEE 613 Query: 463 KMQEQEEKIQRQEEKIQEQEEKTWRQE--------KLLKQEEKIWEQEEKMWRQEEKMWE 514 KM EQEEK+ QEEK+QEQEEK RQE K+ +QEEKI EQEE M QEEKMWE Sbjct: 614 KMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWE 673 Query: 515 QEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERL 561 QEEKM EQEEKMQ QEEKMR QE ++W+QE ++++QE ++QE +E L Sbjct: 674 QEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHL 720 Score = 325 bits (834), Expect = 6e-89 Identities = 206/493 (41%), Positives = 297/493 (60%), Gaps = 72/493 (14%) Query: 66 LSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVK 125 +++ E +N K + + E + E + K+ K L+R LP + +A H+ Sbjct: 275 ITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEA--DHLG 332 Query: 126 KNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQK--RPENSLLE-ETLHF 182 K E++S K Q ++ E W RL + +K R E + E E Sbjct: 333 K---ELQSVSAKLQAQVEENEL-----------WNRLNQQQEEKMWRQEEKIQEWEEKIQ 378 Query: 183 DHAVRMGTYIEKLTKERDAPSLELYRNTITDEELKEKNA---ELQEKLRLVESEKSEIQL 239 + ++ EK+ ++ + + +E+++ + E +EK+R E E + Sbjct: 379 EQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 438 Query: 240 NVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKM 299 +++L+ K+ + + Q++ + E +++ ++ + Q+QE KM Sbjct: 439 KIRELEEKMHEQEKIREQEEKRQEEEKIREQEK-------------------RQEQEAKM 479 Query: 300 WRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIRE------------QEDK 347 WRQEEKI+EQEEK IREQEEKMWRQEEK+HEQE KIRE QE+K Sbjct: 480 WRQEEKIREQEEK-------IREQEEKMWRQEEKIHEQE-KIREEEKRQEQEEMWRQEEK 531 Query: 348 M------WRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQE 401 + WRQ+EKI EQEEKIR+QEEKMWRQEEK+ +Q+EKI+EQEE++WRQEEKIREQE Sbjct: 532 IREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQE 591 Query: 402 EKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEE 461 EK +E QE+K+REQ+E +EQEE+M QEEK+ E EE MQ+QEEK+R EEK++E+E Sbjct: 592 EKIRE----QEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQE 647 Query: 462 EKMQEQEEKIQRQEEKIQEQEEKTWRQ-EKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQ 520 +K++EQEEKI+ QEE +QEQEEK W Q EK+ +QEEK+ EQEEKM RQEEKMWEQE +++ Sbjct: 648 KKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLR 707 Query: 521 EQEEKMQRQEEKM 533 +QEEKMQ +E + Sbjct: 708 QQEEKMQEHQEHL 720 Score = 249 bits (635), Expect = 7e-66 Identities = 167/476 (35%), Positives = 268/476 (56%), Gaps = 61/476 (12%) Query: 21 KSPVLSDEDSDLDFHINKLE-----------QQSKVRNKGHGKPREKSIADEKFFQLSEM 69 K ++ E S++ ++ +L+ QQ H +S++ + Q+ E Sbjct: 290 KLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEEN 349 Query: 70 EAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSD 129 E + +++ K W +++ ++E E+ Q +E R +E I Sbjct: 350 ELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIR-----EQEEKIR------------ 392 Query: 130 EVKSSFKKRQEKMNEKNYTFRKRVVI----KKPWLRLGEVTAQKRPENSLLEETLHFDHA 185 E + ++++E M EK R++ + ++ R E+ +K + LEE +H Sbjct: 393 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEK 452 Query: 186 VRMGTYIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLK 245 +R E+ K ++ + +EK E + K+ E + E + +++ + Sbjct: 453 IR-----EQEEKRQEEEKIRE----------QEKRQEQEAKMWRQEEKIREQEEKIREQE 497 Query: 246 RKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQ--QQEEKMWRQE 303 K+ R + + +Q+ ++ + +E + + + + E+ E+W + +QEEK+ +QE Sbjct: 498 EKMWRQEEKIHEQE-KIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQE 556 Query: 304 EKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIR 363 EK+ QEEKM +QE KIREQEEK+WRQEEK+ EQEEKIRE QEEKIREQEE + Sbjct: 557 EKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIRE-------QEEKIREQEEMTQ 609 Query: 364 EQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIR 423 EQEEKM QEEK+ EQ+EK+QEQEE+M RQEEKIREQE+K +E QE+K+REQ+E ++ Sbjct: 610 EQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIRE----QEEKIREQEEMMQ 665 Query: 424 EQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQ 479 EQEE+MW QEEK+ E EE MQ+QEEK+R EEKM E+E ++++QEEK+Q +E ++ Sbjct: 666 EQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLE 721 >gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 750 Score = 513 bits (1320), Expect = e-145 Identities = 290/496 (58%), Positives = 360/496 (72%), Gaps = 58/496 (11%) Query: 191 YIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLER 250 YIE+LTKERDA SLELYRNTITDEELKEKNA+LQEKL+LVESEKSEIQLNVK+LKRKLER Sbjct: 194 YIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLER 253 Query: 251 AQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQ-------E 303 A+LLLPQQQLQ EAD LGKELQSVSAKLQAQVEENELWN LNQQQEEKMWRQ E Sbjct: 254 AKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWE 313 Query: 304 EKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIR------- 356 EKIQEQEEK+ EQE KIREQEEKM RQEE M E+EEK+R QE+ MW +EEK+R Sbjct: 314 EKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMW 373 Query: 357 EQEEKIREQEEKMWRQEEKIREQDEKI-------------------------QEQEEEMW 391 E+EEK+R QEE MW +EEKIRE +EK+ QEQE +MW Sbjct: 374 EKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMW 433 Query: 392 RQEEKIREQEEK---RQEKMWRQEKKMREQDEKIREQE-----EEMWRQEEKIRELEEMM 443 RQEEKIREQEEK +++KMWRQE+K+ EQ EKIRE+E EEMWRQEEKI E EE+ Sbjct: 434 RQEEKIREQEEKIREQEKKMWRQEEKIHEQ-EKIREEEKRQEQEEMWRQEEKIHEQEEIW 492 Query: 444 QDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEE 503 + Q+EK+ E EEK++++EEK+ QEEKI+ QEEKI+EQEEK WRQE+ ++++E++W +EE Sbjct: 493 R-QKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEE 551 Query: 504 KMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGK 563 KM ++EK+WE EEK QEQE+KM RQEEK+REQE ++W+QEEK++EQE + QE EE++ K Sbjct: 552 KM-HEQEKIWE-EEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWK 609 Query: 564 LGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQQYVAAYQQL 623 +K RE + I + E K +E + + Q+Q+ G ++ + ++ Sbjct: 610 QEEKI-------REQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEK 662 Query: 624 ASGKEALPSCSSRKLR 639 +E K+R Sbjct: 663 MQEQEETMWRQEEKIR 678 Score = 389 bits (1000), Expect = e-108 Identities = 242/539 (44%), Positives = 331/539 (61%), Gaps = 58/539 (10%) Query: 66 LSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVK 125 +++ E +N K + + E + E + K+ K L+R LP + +A H+ Sbjct: 214 ITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEA--DHLG 271 Query: 126 KNSDEVKSSFKKRQEK---MNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHF 182 K V + + + E+ N N +++ ++ ++ E Q++ E +E Sbjct: 272 KELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIR 331 Query: 183 DHAVRMGTYIEKLTKERDAPSLELYRNTITDEELKEKNA---ELQEKLRLVESEKSEIQL 239 + +M E + ++ + + +E+++ + E +EK+R E E + Sbjct: 332 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 391 Query: 240 NVKDLKRKLERAQLLLPQQQLQVEADRLGKE--LQSVSAKLQAQVEENELWNLLNQQQEE 297 +++L+ K+ + + Q++ + E +++ ++ Q AK+ Q E+ ++QE+ Sbjct: 392 KIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEK 451 Query: 298 KMWRQEEKIQEQE-----------EKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQED 346 KMWRQEEKI EQE E+M QE KI EQEE +WRQ+EKMHEQEEKIR+QE+ Sbjct: 452 KMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEE-IWRQKEKMHEQEEKIRKQEE 510 Query: 347 KMWRQEEKIREQEEKIREQEEKMWRQEEKIRE---------------------------- 378 K+WRQEEKIREQEEKIREQEEKMWRQEEKIRE Sbjct: 511 KVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQED 570 Query: 379 ----QDEKIQEQEEEMWRQEEKIREQEEKRQ---EKMWRQEKKMREQDEKIREQEEEMWR 431 Q+EKI+EQEE++WRQEEKIREQEEKRQ EKMW+QE+K+REQ+EKI+EQEE++ Sbjct: 571 KMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIRE 630 Query: 432 QEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQ-EK 490 QEEKIRE EEM Q+QEEK+ E EEKM E+EEKMQEQEE + RQEEKI+EQE+K Q EK Sbjct: 631 QEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEK 690 Query: 491 LLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQE 549 + +QEE + EQEEKMW QEEKM EQEEKMQEQEEKM+RQEEKM EQEVRL QQEEKMQE Sbjct: 691 IREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749 Score = 247 bits (631), Expect = 2e-65 Identities = 163/435 (37%), Positives = 247/435 (56%), Gaps = 85/435 (19%) Query: 38 KLEQQSKVRNKGHGKPREKSIADEKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSK 97 K+ +Q K+R + + E+ I ++ E R+ + K W +++ + E E+ Sbjct: 399 KMHEQEKIREQEEKRQEEEKIREQ------------EKRQEQEAKMWRQEEKIREQEE-- 444 Query: 98 QCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKK 157 + +E K++ +E I + QEK+ E+ KR ++ Sbjct: 445 KIREQEKKM---WRQEEKIHE--------------------QEKIREE----EKRQEQEE 477 Query: 158 PWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEELK 217 W R E + E+ + +M EK+ K+ + +++R E + Sbjct: 478 MW----------RQEEKIHEQEEIWRQKEKMHEQEEKIRKQEE----KVWRQEEKIREQE 523 Query: 218 EKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAK 277 EK E +EK+ E + E Q+++ E +++ E + + + Sbjct: 524 EKIREQEEKMWRQEEKIRE--------------------QEEMWREEEKM-HEQEKIWEE 562 Query: 278 LQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQ 337 + Q +E+++W +QEEK+ QEEK+ QEEK+ EQE K +EQEEKMW+QEEK+ EQ Sbjct: 563 EKRQEQEDKMW-----RQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQ 617 Query: 338 EEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKI 397 EEKI+EQE+K+ QEEKIREQEE +EQEEKM QEEK+ EQ+EK+QEQEE MWRQEEKI Sbjct: 618 EEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKI 677 Query: 398 REQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKM 457 REQE+K +E QE+K+REQ+E ++EQEE+MW QEEK+ E EE MQ+QEEK+R EEKM Sbjct: 678 REQEKKIRE----QEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKM 733 Query: 458 QEEEEKMQEQEEKIQ 472 E+E ++++QEEK+Q Sbjct: 734 WEQEVRLRQQEEKMQ 748 >gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 828 Score = 424 bits (1090), Expect = e-118 Identities = 228/389 (58%), Positives = 303/389 (77%), Gaps = 43/389 (11%) Query: 191 YIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLER 250 YIE+LTKERDA SLELYRNTIT+EELK+KNAELQEKLRL ESEKSEIQLNVK+LKRKLER Sbjct: 160 YIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLER 219 Query: 251 AQLLLPQQQ---LQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQ 307 A+ LLPQ Q LQ E R +EL+ K+ ++QEEKMWRQEE+++ Sbjct: 220 AKFLLPQVQTNTLQEEMWRQEEELREQEKKI--------------RKQEEKMWRQEERLR 265 Query: 308 EQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEE 367 EQE KM REQEEKM RQE+++ EQE+++REQE ++ R+++K+REQEE+++EQEE Sbjct: 266 EQEGKM-------REQEEKMRRQEKRLREQEKELREQEKEL-REQKKLREQEEQMQEQEE 317 Query: 368 KMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEK---RQEKMWRQEKKMREQDEKIRE 424 KMW QEEK+REQ+EK+ QEE +W QE+++REQE+K ++E+MW Q++++RE++E++RE Sbjct: 318 KMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMRE 377 Query: 425 QEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEK------I 478 Q E+MW QEEK++E EE ++++E+K+RE EE M+E+EEKMQ+QEE + QEEK + Sbjct: 378 Q-EKMWEQEEKMQE-EERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRL 435 Query: 479 QEQEEKTWRQEKLLKQEEKIWEQEEK------MWRQEEKMWEQEEKMQEQEEKMQRQEEK 532 EQ+EK W QEK+ +QEEKIWEQEEK MW QE+KMW Q EKM+EQE++M QEEK Sbjct: 436 PEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQ-EKMREQEDQMWEQEEK 494 Query: 533 MREQEVRLWQQEEKMQEQEVRLQELEERL 561 MR+QE ++W QEE+M EQ+ RL+E EER+ Sbjct: 495 MRDQEQKMWDQEERMWEQDERLREKEERM 523 Score = 348 bits (894), Expect = 7e-96 Identities = 223/559 (39%), Positives = 346/559 (61%), Gaps = 54/559 (9%) Query: 21 KSPVLSDEDSDLDFHINKLEQQSKVRNKGHGKPREKSIADEKFFQLSEMEAYLENRKRRG 80 K + E S++ ++ +L+++ + + + ++ +E + Q E+ + +++ Sbjct: 195 KLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQE 254 Query: 81 TKRWDEDDDLEESEDS-KQCKESLKRVTFTLPDDEAI--EDAGVSHVKKNSDEVKSSFKK 137 K W +++ L E E ++ +E ++R L + E E +K E + ++ Sbjct: 255 EKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQE 314 Query: 138 RQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTK 197 ++EKM E+ R++ +K W R E L E+ E+ K Sbjct: 315 QEEKMWEQEEKMREQE--EKMW----------RQEERLWEQEKQMR---------EQEQK 353 Query: 198 ERDAPSLELYRNTITDEELKEKNAELQEKLRLVESE-KSEIQLNVKDLKRKLERAQLLLP 256 RD R DE L+EK ++E+ ++ E E K + + +++ ++K+ + + Sbjct: 354 MRDQEE----RMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMR 409 Query: 257 QQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQ 316 +Q+ +++Q + Q EE E +Q+EK+W QE K+QEQEEK+ EQ Sbjct: 410 EQE---------EKMQKQEENMWEQ-EEKEWQQQRLPEQKEKLWEQE-KMQEQEEKIWEQ 458 Query: 317 ELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKI 376 E KIR+QEE MW QE+KM QE K+REQED+MW QEEK+R+QE+K+ +QEE+MW Q+E++ Sbjct: 459 EEKIRDQEE-MWGQEKKMWRQE-KMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERL 516 Query: 377 REQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKI 436 RE++E+++EQ ++MW+QEEK+RE E+K QE QEKK +Q+EK+RE EE M +E+K+ Sbjct: 517 REKEERMREQ-KKMWQQEEKMRE-EKKTQE----QEKKTWDQEEKMRE-EERMREREKKM 569 Query: 437 RELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQE---KLLK 493 RE EEMM++QEEK++E EEKM+E+EEKM EQEEK+Q QEEK+ EQEEK W QE K+ + Sbjct: 570 REEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQE 629 Query: 494 QEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVR 553 QEE +WEQEEKM QEEKMWEQEEKM+EQEEKM+ QEEKM+ QE ++ +QEEKMQ QE + Sbjct: 630 QEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEK 689 Query: 554 LQELEERLGKLGQKAELLG 572 ++E EE++ GQ+ ++ G Sbjct: 690 MREQEEKM--RGQEEKMWG 706 Score = 203 bits (517), Expect = 4e-52 Identities = 125/383 (32%), Positives = 224/383 (58%), Gaps = 51/383 (13%) Query: 272 QSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQE 331 +++ +++AQ + + E ++ ++ ++ E+ + + + W Sbjct: 81 EALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGESKDLAGRLHHSWHFA 140 Query: 332 EKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQ----- 386 ++ + K R E++ ++ + + + + E++++++ ++QE+ Sbjct: 141 GELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAE 200 Query: 387 --------------------------------EEEMWRQEEKIREQEE---KRQEKMWRQ 411 +EEMWRQEE++REQE+ K++EKMWRQ Sbjct: 201 SEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQ 260 Query: 412 EKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKI 471 E+++REQ+ K+REQEE+M RQE+++RE E+ +++QE++LRE ++K++E+EE+MQEQEEK+ Sbjct: 261 EERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELRE-QKKLREQEEQMQEQEEKM 319 Query: 472 QRQEEKIQEQEEKTWRQ-EKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQE------E 524 QEEK++EQEEK WRQ E+L +QE+++ EQE+KM QEE+MWEQ+E+++E+E E Sbjct: 320 WEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQE 379 Query: 525 KMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLP 584 KM QEEKM+E+E R+ ++E+KM+E+E ++E EE++ K Q+ + +E QRLP Sbjct: 380 KMWEQEEKMQEEE-RIREREKKMREEEETMREQEEKMQK--QEENMWEQEEKEWQQQRLP 436 Query: 585 TLTPILQVELKSQEAQSLQQQQD 607 L + K QE + +Q+ Sbjct: 437 EQKEKLWEQEKMQEQEEKIWEQE 459 Score = 200 bits (508), Expect = 4e-51 Identities = 140/433 (32%), Positives = 242/433 (55%), Gaps = 53/433 (12%) Query: 38 KLEQQSKVRNKGHGKPREKSIADEKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSK 97 +L +Q K + K R++ +E+ ++ E E R R K W++++ ++E E + Sbjct: 339 RLWEQEKQMREQEQKMRDQ---EERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIR 395 Query: 98 QCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEV---------------KSSFKKRQEKM 142 + ++ ++ T+ + E ++ + ++ + ++++EK+ Sbjct: 396 EREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKI 455 Query: 143 NEKNYTFRKRVVI----KKPW----LRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEK 194 E+ R + + KK W +R E ++ E +E +D RM E+ Sbjct: 456 WEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDER 515 Query: 195 LTKERDAPSLELYRNTITDEELKE-KNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQL 253 L +E++ E + +E+++E K + QEK + EK + +++ ++K+ + Sbjct: 516 L-REKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEE 574 Query: 254 LLPQQQ--LQVEADRLGKELQSV-SAKLQAQVEENELWNLLNQQQEEKMWRQEE--KIQE 308 ++ +Q+ +Q + +++ ++ + + + + Q +E ++W +QEEKMW QEE K+QE Sbjct: 575 MMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMW-----EQEEKMWEQEEEDKMQE 629 Query: 309 QEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEK 368 QEE M EQE K++EQEEKMW QEEKM EQEEK+REQE+KM QEEK+REQEEK++ QEEK Sbjct: 630 QEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEK 689 Query: 369 MWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEE 428 M QEEK+R Q+EK+ QEE+MW QE EKMW QE +MRE++E+IR+Q+E+ Sbjct: 690 MREQEEKMRGQEEKMWGQEEKMWGQE-----------EKMWGQE-EMREKEERIRDQKEK 737 Query: 429 MWRQEEKIRELEE 441 M +E++ E EE Sbjct: 738 M---QERLPEHEE 747 Score = 134 bits (337), Expect = 3e-31 Identities = 95/339 (28%), Positives = 182/339 (53%), Gaps = 28/339 (8%) Query: 294 QQEEKMWRQEEKIQEQEEKMCEQELKI-----REQEEKMWRQEEKMHEQEE-KIREQED- 346 + E+K Q ++ +E + + ++I E E ++ ++ + E+ + E +D Sbjct: 70 EDEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGESKDL 129 Query: 347 -----KMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQE 401 W +++ + +K R E++ ++ + + + E+++++ Sbjct: 130 AGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKN 189 Query: 402 EKRQEKMWRQEKKMREQDEKIREQEEEMWRQ-----EEKIRELEEMMQDQEEKLREVEEK 456 + QEK+ E + E ++E + ++ R + + L+E M QEE+LRE E+K Sbjct: 190 AELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKK 249 Query: 457 MQEEEEKMQE-----QEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEK 511 + + QE QEE+++ QE K++EQEEK RQEK L+++EK ++EK R+++K Sbjct: 250 I-----RKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKK 304 Query: 512 MWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELL 571 + EQEE+MQEQEEKM QEEKMREQE ++W+QEE++ EQE +++E E+++ ++ Sbjct: 305 LREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQ 364 Query: 572 GGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYR 610 RE +R+ + + E K QE + +++++ R Sbjct: 365 DERLREK-EERMREQEKMWEQEEKMQEEERIREREKKMR 402 Score = 41.6 bits (96), Expect = 0.002 Identities = 51/279 (18%), Positives = 118/279 (42%), Gaps = 38/279 (13%) Query: 395 EKIREQEEKRQEKMWRQEKKMRE---QDEKIR-------EQEEEMWRQEEKIRELEEMMQ 444 E E++++ QE RE QD IR E E ++ ++ R+ E+ Sbjct: 64 EGCHSPEDEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNL 123 Query: 445 DQEEKLR-------EVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEE--------KTWRQE 489 + + L ++Q + +K R E++ ++ + T E Sbjct: 124 GESKDLAGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNE 183 Query: 490 KLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVR-----LWQQE 544 +L K+ ++ +EK+ E + E + ++E + K++R + + + + +W+QE Sbjct: 184 ELKKKNAEL---QEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQE 240 Query: 545 EKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQ 604 E+++EQE ++++ EE++ + ++ G RE + + + E + +E + + Sbjct: 241 EELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELR 300 Query: 605 QQDHYRGHLQQYVAAYQQLASGKEALPSCSSRKLRAKRW 643 +Q R +Q +++ +E + R+ K W Sbjct: 301 EQKKLREQEEQMQEQEEKMWEQEEKM-----REQEEKMW 334 >gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 899 Score = 419 bits (1078), Expect = e-117 Identities = 249/505 (49%), Positives = 333/505 (65%), Gaps = 106/505 (20%) Query: 191 YIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLER 250 YIE+LTKERDA SLELYRNTIT+EELK+KNAELQEKL L ESEKSEIQLNVK+LKRKLER Sbjct: 198 YIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLER 257 Query: 251 AQLLLPQQQ---LQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQ 307 A+ LLPQ Q LQ E R +EL+ K++ Q E ++W +QEE++ QE K++ Sbjct: 258 AKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQ--EEKMW-----RQEERLREQEGKMR 310 Query: 308 EQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEE 367 EQEEKM QE ++REQE+++ QE+++ EQ+E +REQE++M QEEK+ EQEEK+REQEE Sbjct: 311 EQEEKMWRQEKRLREQEKELREQEKELREQKE-LREQEEQMQEQEEKMWEQEEKMREQEE 369 Query: 368 KMWRQEEKI-------REQDEKIQEQEEEMWRQEEKIREQEE--KRQEKMW------RQE 412 KMWRQEE++ REQ++K+++QEE MW Q+E++RE+EE + QEKMW R+E Sbjct: 370 KMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREE 429 Query: 413 KKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQE------------- 459 KKM+EQ++K R+QEE+M ++EE+IRE E+ M+++EE +RE EEKMQ+ Sbjct: 430 KKMQEQEKKTRDQEEKM-QEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEW 488 Query: 460 -------------EEEKMQEQEEKIQRQEEKIQEQEE------KTWRQEKLLKQEEKIWE 500 E+EKMQEQEEKI QEEKI++QEE K WRQEK+ +QE+++WE Sbjct: 489 QQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWE 548 Query: 501 QEEKMWRQEEKMWEQEEKMQ--------------------------------------EQ 522 QEEKM QE+KMW+QEE+M+ EQ Sbjct: 549 QEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQ 608 Query: 523 EEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQR 582 EEKMQ QEEKM+EQE ++W+QEEKMQEQE ++ E EE++ + +K QR Sbjct: 609 EEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKM---------WEQQR 659 Query: 583 LPTLTPILQVELKSQEAQSLQQQQD 607 LP L K QE + +Q+Q++ Sbjct: 660 LPEQKEKLWEHEKMQEQEKMQEQEE 684 Score = 345 bits (884), Expect = 1e-94 Identities = 222/666 (33%), Positives = 380/666 (57%), Gaps = 87/666 (13%) Query: 21 KSPVLSDEDSDLDFHINKLEQQSKVRNKGHGKPREKSIADEKFFQLSEMEAYLENRKRRG 80 K P+ E S++ ++ +L+++ + + + ++ +E + Q E+ + +++ Sbjct: 233 KLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQE 292 Query: 81 TKRWDEDDDLEESEDS-KQCKESLKRVTFTLPDDEAI--EDAGVSHVKKNSDEVKSSFKK 137 K W +++ L E E ++ +E + R L + E E +K E + ++ Sbjct: 293 EKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQE 352 Query: 138 RQEKMNEKNYTFRKRVVIKKPWL---RLGEVTAQKRPENS---------------LLEET 179 ++EKM E+ R++ +K W RL E Q R + L E+ Sbjct: 353 QEEKMWEQEEKMREQE--EKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKE 410 Query: 180 LHFDHAVRMGTYIEKLTKER-----DAPSLELYRNTITDEELKEKNAELQEKLRLVESEK 234 +M +EK+ +E+ + + + +E ++E+ +++E+ + ++ Sbjct: 411 ERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQE 470 Query: 235 SEIQLNVKDL----------KRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEE 284 ++Q +++ +R E+ + L Q+++Q + +++ ++ + + + + +E Sbjct: 471 EKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQE 530 Query: 285 NELWNLLN-QQQEEKMWRQEEKIQEQEEKMCEQE----LKIREQEEKMWRQEEKMHEQE- 338 ++W ++QE++MW QEEK+++QE+KM +QE K +EQE+K W QEEKM E+E Sbjct: 531 KKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEER 590 Query: 339 -----EKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQ 393 +K+RE+E+ M QEEK++EQEEK++EQEEKMW QEEK++EQ+EK+ EQEE+MW Q Sbjct: 591 MREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQ 650 Query: 394 EEKIREQEE--KRQEKMWRQEK-----KMREQDEKIREQE---------------EEMWR 431 EEK+ EQ+ +++EK+W EK KM+EQ+EKI EQE +E R Sbjct: 651 EEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMR 710 Query: 432 QEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKL 491 +EE +RE E+ M+++EE +RE EEKMQE+EEKMQEQEE++ QEEK+ EQEEK W Q++L Sbjct: 711 EEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRL 770 Query: 492 LKQEEKIWEQE-----EKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEK 546 +Q+EK+WE E EK+W QEEKM +QEEKM+ QEEKM+ QEEKMR QE ++W QEEK Sbjct: 771 PEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEK 830 Query: 547 MQEQEVRLQELEERL-GKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQ 605 M QE ++ EE++ G+ + E + G + Q + +++ QE + +++Q Sbjct: 831 MWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQ---------EEKMRGQE-EKMREQ 880 Query: 606 QDHYRG 611 ++ RG Sbjct: 881 EEKMRG 886 Score = 332 bits (850), Expect = 9e-91 Identities = 221/587 (37%), Positives = 337/587 (57%), Gaps = 111/587 (18%) Query: 40 EQQSKVRNKGHGKPREKSIADEKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQC 99 EQ+ K+R + R++ E+ Q+ E E + +++ R W++D+ L E E+ + Sbjct: 359 EQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEER---MWEQDERLREKEERMRE 415 Query: 100 KESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSS-----FKKRQEKMNEKNYTFRKRVV 154 +E + + +++ +++ KK D+ + ++R++KM E+ T R++ Sbjct: 416 QEKMWEQVEKMREEKKMQE----QEKKTRDQEEKMQEEERIREREKKMREEEETMREQ-- 469 Query: 155 IKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDAPSLELYRNTITDE 214 E QK+ EN +E EK +++ P Sbjct: 470 ---------EEKMQKQEENMWEQE--------------EKEWQQQRLP------------ 494 Query: 215 ELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSV 274 E KEK E QEK++ E + E + ++D + + + + Q++++ + D++ ++ + + Sbjct: 495 EQKEKLWE-QEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKM 553 Query: 275 SAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKM 334 + Q ++ E Q+QE+K W QEEK++E EE+M E+E K+RE+EE M QEEKM Sbjct: 554 RDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMRE-EERMREREKKMREEEEMMREQEEKM 612 Query: 335 HEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQD-------------- 380 EQEEK++EQE+KMW QEEK++EQEEK+ EQEEKMW QEEK+ EQ Sbjct: 613 QEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEK 672 Query: 381 ----EKIQEQEEEMWRQE----------------EKIREQEEKRQ---------EKMWRQ 411 EK+QEQEE++W QE EK+RE+E R+ E M Q Sbjct: 673 MQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQ 732 Query: 412 EKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQE------------EKLREVEEKMQE 459 E+KM+EQ+EK++EQEEEMW QEEK+ E EE M +Q+ EK++E +EK+ E Sbjct: 733 EEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQE-QEKIWE 791 Query: 460 EEEKMQEQEEKIQRQEEKIQEQEEK-TWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEK 518 +EEKM++QEEK++ QEEK++ QEEK ++EK+ QEEK+W QEEKMW QEEKMW QEEK Sbjct: 792 QEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEK 851 Query: 519 MQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLG 565 M EEKMQ QEEKMREQE ++ QEEKM+EQE +++ EE++ +G Sbjct: 852 M---EEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEKIYCVG 895 Score = 204 bits (518), Expect = 3e-52 Identities = 125/346 (36%), Positives = 203/346 (58%), Gaps = 69/346 (19%) Query: 328 WRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQ- 386 W ++ + + K R E++ ++ + + + + E++++++ ++QE+ Sbjct: 175 WHFAGELQRALSAVSTRHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKL 234 Query: 387 ------------------------------------EEEMWRQEEKIREQEE---KRQEK 407 +EEMWRQEE++REQE+ K++EK Sbjct: 235 PLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEK 294 Query: 408 MWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQE------EKLREVEEKMQEEE 461 MWRQE+++REQ+ K+REQEE+MWRQE+++RE E+ +++QE ++LRE EE+MQE+E Sbjct: 295 MWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQE 354 Query: 462 EKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLK-QEEKIWEQEEKMW-------------R 507 EKM EQEEK++ QEEK+ QEE+ W QEK ++ QE+K+ +QEE+MW R Sbjct: 355 EKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMR 414 Query: 508 QEEKMWEQ------EEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERL 561 ++EKMWEQ E+KMQEQE+K + QEEKM+E+E R+ ++E+KM+E+E ++E EE++ Sbjct: 415 EQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEE-RIREREKKMREEEETMREQEEKM 473 Query: 562 GKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQD 607 K Q+ + +E QRLP L + K QE + +Q+ Sbjct: 474 QK--QEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQE 517 Score = 148 bits (373), Expect = 2e-35 Identities = 135/484 (27%), Positives = 233/484 (48%), Gaps = 64/484 (13%) Query: 134 SFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIE 193 S K RQ K+ E +K+ + W G T + + + + G + Sbjct: 14 SEKTRQNKLAEA----KKKFTDYRQWNIAGVGTGATDTKKKKINHGTNPETTTSGGCHSP 69 Query: 194 KLTKERDAPSLELYRNTITDEELKEKNAELQEK-LRLVESEKSEIQLNV---KDLKRKLE 249 + T++ A E + + +E + E Q+ +R++ +K+E++ + +D RK E Sbjct: 70 EDTQQNRAQLKEEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFE 129 Query: 250 RAQLLLPQQ-QLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQE 308 L P L + G L VS L E +L L+ W ++Q Sbjct: 130 DGNLGTPSSFNLALSQAFRGSPLGCVSTSL-IPGESKDLAGRLHHS-----WHFAGELQR 183 Query: 309 QEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEK 368 + + K E++ ++ + + + ++R E ++K E +EK Sbjct: 184 ALSAVSTRHKKADRYIEELTKERDALSLE----------LYRNTITNEELKKKNAELQEK 233 Query: 369 MWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEE 428 + E + E IQ +E+ R+ E+ K + +EE Sbjct: 234 LPLAESEKSE----IQLNVKELKRKLERA----------------KFLLPQVQTNTLQEE 273 Query: 429 MWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQ 488 MWRQEE++RE E+ ++ QEEK+ EE+++E+E KM+EQEEK+ RQE++++EQE++ Q Sbjct: 274 MWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQ 333 Query: 489 EKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQ 548 EK L++++++ EQEE+M QEEKMWEQEEKM+EQEEKM RQEE RLW+QE++M Sbjct: 334 EKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEE-------RLWEQEKQM- 385 Query: 549 EQEVRLQE--LEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQ 606 R QE + ++ ++ ++ E L RE +R+ + + K +E + +Q+Q+ Sbjct: 386 ----REQEQKMRDQEERMWEQDERL----REK-EERMREQEKMWEQVEKMREEKKMQEQE 436 Query: 607 DHYR 610 R Sbjct: 437 KKTR 440 Score = 40.8 bits (94), Expect = 0.004 Identities = 36/201 (17%), Positives = 92/201 (45%), Gaps = 14/201 (6%) Query: 449 KLREVEEKMQEEEEKMQEQEEKIQRQEEKIQ-EQEEKTWRQEKLLKQEEKIWEQEEKMWR 507 +L+ + +K E++ ++ + + E T E+L K+ ++ +EK+ Sbjct: 180 ELQRALSAVSTRHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAEL---QEKLPL 236 Query: 508 QEEKMWEQEEKMQEQEEKMQRQEEKMREQEVR-----LWQQEEKMQEQEVRLQELEERLG 562 E + E + ++E + K++R + + + + +W+QEE+++EQE ++++ EE++ Sbjct: 237 AESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMW 296 Query: 563 KLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQQYVAAYQQ 622 + ++ G RE + + + E + +E + ++Q R +Q ++ Sbjct: 297 RQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEK 356 Query: 623 LASGKEALPSCSSRKLRAKRW 643 + +E + R+ K W Sbjct: 357 MWEQEEKM-----REQEEKMW 372 >gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapiens] Length = 436 Score = 319 bits (818), Expect = 4e-87 Identities = 178/419 (42%), Positives = 292/419 (69%), Gaps = 48/419 (11%) Query: 211 ITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKE 270 IT+EELKEKNAELQE+L+LVE+EKSEIQL++K+LKRKLE ++ LPQ+ E + +E Sbjct: 4 ITNEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVRE 63 Query: 271 LQSVSAKLQAQVEENELWNLLNQ---------------------------------QQEE 297 + + + QV E E + Q +QE Sbjct: 64 QEGQVREQEGQVREQE-GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 122 Query: 298 KMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIRE 357 ++ QE +++EQE ++ EQE ++REQE ++ QE ++ EQE ++REQE ++ QE ++RE Sbjct: 123 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 182 Query: 358 QEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEE---KRQEKMWRQEKK 414 QE ++REQE +M QE ++ EQ+E++ EQEE+M +QEE++ EQEE K++E+M QE++ Sbjct: 183 QEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQ 242 Query: 415 MREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKL------REVEEKMQEEEEKMQEQE 468 +++Q+E++++QEE+M +QEE++RE EE M++QEE++ E EE+ E+EE+M+EQE Sbjct: 243 VQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQE 302 Query: 469 EKIQRQEEKIQEQEEKTWRQEKLL-KQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQ 527 E+++ QEE+++EQEE+ QE+ + KQEE++WEQ+E+MW Q+E+MW+QEE+M EQEE+MQ Sbjct: 303 EQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQ 362 Query: 528 RQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLG----KLGQKAELLGGAGRESGSQR 582 +QEE++R+QE ++ +QEE+M++QE ++++ EE++G ++G++ E + + G Q+ Sbjct: 363 KQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQK 421 Score = 266 bits (681), Expect = 3e-71 Identities = 152/398 (38%), Positives = 279/398 (70%), Gaps = 38/398 (9%) Query: 215 ELKEKNAELQEK---LRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQV-EADRLGKE 270 +++E+ +++E+ +R E + E + V++ + ++ + + +Q+ QV E + +E Sbjct: 67 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 126 Query: 271 LQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQ 330 + + + QV E E ++QE ++ QE +++EQE ++ EQE ++REQE ++ Q Sbjct: 127 QEGQVREQEGQVREQEGQV---REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 183 Query: 331 EEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEM 390 E ++ EQE ++ EQE +M QEE++ EQEE++++QEE+M QEE++R+Q+E++ EQEE++ Sbjct: 184 EGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQV 243 Query: 391 WRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKL 450 +QEE++++QE E+M +QE++MREQ+E++REQEE+M +Q+E+ E EE +QEE++ Sbjct: 244 QKQEEQVQKQE----EQMRKQEEQMREQEEQMREQEEQMLKQKEQ-TEQEEQTGEQEEQM 298 Query: 451 REVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEE 510 RE EE+M+E+EE+M+EQEE+++ QEE++ +QEE+ W +Q+E++WEQ+E+MW+QEE Sbjct: 299 REQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMW------EQKEQMWEQKEQMWKQEE 352 Query: 511 KMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAEL 570 +M EQEE+MQ+QEE++++QEE+MR+QE ++ +QEE+M++QE ++ E +E++G+ QK ++ Sbjct: 353 QMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGE--QKEQM 410 Query: 571 LGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDH 608 RE Q E ++ + +++Q++H Sbjct: 411 -----RE-------------QEEQMGEQKEQMRKQEEH 430 Score = 257 bits (657), Expect = 2e-68 Identities = 143/352 (40%), Positives = 259/352 (73%), Gaps = 10/352 (2%) Query: 215 ELKEKNAELQEK---LRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQV-EADRLGKE 270 +++E+ +++E+ +R E + E + V++ + ++ + + +Q+ QV E + +E Sbjct: 88 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 147 Query: 271 LQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQ 330 + + + QV E E ++QE ++ QE +++EQE ++ EQE ++ EQE +M Q Sbjct: 148 QEGQVREQEGQVREQEGQV---REQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQ 204 Query: 331 EEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEM 390 EE+M EQEE++++QE++M QEE++R+QEE++ EQEE++ +QEE++++Q+E++++QEE+M Sbjct: 205 EEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQM 264 Query: 391 WRQEEKIREQEEK--RQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEE 448 QEE++REQEE+ +Q++ QE++ EQ+E++REQEE+M QEE++RE EE M++QEE Sbjct: 265 REQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEE 324 Query: 449 KLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQ-EKLLKQEEKIWEQEEKMWR 507 ++ + EE+M E++E+M EQ+E++ +QEE++ EQEE+ +Q E++ KQEE++ +QEE+M + Sbjct: 325 QMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRK 384 Query: 508 QEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEE 559 QEE+M +QEE+M EQ+E+M Q+E+MREQE ++ +Q+E+M++QE + E +E Sbjct: 385 QEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436 Score = 201 bits (512), Expect = 1e-51 Identities = 117/341 (34%), Positives = 215/341 (63%), Gaps = 18/341 (5%) Query: 290 LLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMW 349 + N++ +EK +E++Q E + E +L I+E + K+ + + QE ++REQE ++ Sbjct: 4 ITNEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPL-PQEGQVREQEGQVR 62 Query: 350 RQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMW 409 QE ++REQE ++REQE ++ QE ++REQ+ +++EQE ++ QE ++REQE + +E Sbjct: 63 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE--- 119 Query: 410 RQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEE 469 QE ++REQ+ ++REQE ++ QE ++RE E +++QE ++RE E +++E+E +++EQE Sbjct: 120 -QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 178 Query: 470 KIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQ 529 +++ QE +++EQE + + EQE +M QEE+M EQEE+MQ+QEE+M Q Sbjct: 179 QVREQEGQVREQEGQ-------------MGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQ 225 Query: 530 EEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPI 589 EE+MR+QE ++ +QEE++Q+QE ++Q+ EE++ K ++ RE Q L Sbjct: 226 EEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQT 285 Query: 590 LQVELKSQEAQSLQQQQDHYRGHLQQYVAAYQQLASGKEAL 630 Q E ++ + +++Q++ R +Q +Q+ +E + Sbjct: 286 EQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQM 326 Score = 172 bits (437), Expect = 7e-43 Identities = 92/236 (38%), Positives = 163/236 (69%), Gaps = 4/236 (1%) Query: 213 DEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQ 272 +E++ E+ ++Q++ + ++ +++ + + + E+ Q Q Q Q E R +E Sbjct: 205 EEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQM 264 Query: 273 SVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEE 332 + + EE L +QEE+ QEE+++EQEE+M EQE ++REQEE+M QEE Sbjct: 265 REQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEE 324 Query: 333 KMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWR 392 +M +QEE++ EQ+++MW Q+E++ +QEE++ EQEE+M +QEE++R+Q+E++++QEE+M + Sbjct: 325 QMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRK 384 Query: 393 QEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEE 448 QEE++R+QE E+M Q+++M EQ E++REQEE+M Q+E++R+ EE M +Q+E Sbjct: 385 QEEQMRKQE----EQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436 Score = 160 bits (405), Expect = 3e-39 Identities = 108/421 (25%), Positives = 242/421 (57%), Gaps = 23/421 (5%) Query: 24 VLSDEDSDLDFHINKLEQQ---SKVRNKGHGKPREKS-IADEKFFQLSEMEAYLEN---- 75 ++ E S++ HI +L+++ K+ G+ RE+ E+ Q+ E E + Sbjct: 22 LVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 81 Query: 76 -RKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSS 134 R++ G R E E+ ++ + ++ + + E V++ +V+ Sbjct: 82 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 141 Query: 135 ---FKKRQEKMNEKNYTFRKRV-VIKKPWLRLGEVTAQKRPENSLL--EETLHFDHAVRM 188 ++++ ++ E+ R++ +++ ++ E Q R + + +E + +M Sbjct: 142 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQM 201 Query: 189 GTYIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKL 248 G E++ ++ + + + +E+++++ ++ E+ V+ ++ ++Q + ++++ Sbjct: 202 GEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQE 261 Query: 249 ERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQ--QQEEKMWRQEEKI 306 E Q+ ++Q++ + +++ K+ + + Q +E ++ Q +QEE+M QEE++ Sbjct: 262 E--QMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQM 319 Query: 307 QEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQE 366 +EQEE+M +QE ++ EQ+E+MW Q+E+M +QEE++ EQE++M +QEE++R+QEE++R+QE Sbjct: 320 REQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQE 379 Query: 367 EKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQE 426 E+M +QEE++R+Q+E++ EQ+E+M Q+E++REQE E+M Q+++MR+Q+E + EQ+ Sbjct: 380 EQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQE----EQMGEQKEQMRKQEEHMGEQK 435 Query: 427 E 427 E Sbjct: 436 E 436 Score = 114 bits (286), Expect = 2e-25 Identities = 78/275 (28%), Positives = 165/275 (60%), Gaps = 18/275 (6%) Query: 377 REQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIR-EQEEEMWRQEEK 435 R +E+++E+ E+ QEE + EK + ++ +E K + + +KI QE ++ QE + Sbjct: 3 RITNEELKEKNAEL--QEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQ 60 Query: 436 IRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQE-KLLKQ 494 +RE E +++QE ++RE E +++E+E +++EQE +++ QE +++EQE + QE ++ +Q Sbjct: 61 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 120 Query: 495 EEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRL 554 E ++ EQE ++ QE ++ EQE +++EQE +++ QE ++REQE ++ +QE +++EQE ++ Sbjct: 121 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 180 Query: 555 QELE----ERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYR 610 +E E E+ G++G++ +G + G Q + +++ QE Q + +Q++ R Sbjct: 181 REQEGQVREQEGQMGEQEGQMGEQEEQMGEQ---------EEQMQKQEEQ-MGEQEEQMR 230 Query: 611 GHLQQYVAAYQQLASGKEALPSCSSRKLRAKRWLR 645 +Q +Q+ +E + + + + +R Sbjct: 231 KQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMR 265 >gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] Length = 523 Score = 229 bits (583), Expect = 8e-60 Identities = 140/379 (36%), Positives = 231/379 (60%), Gaps = 56/379 (14%) Query: 231 ESEKSEIQLNVKDLKRKL-----ERAQLLLPQ--------QQLQVEADRLGKELQSVSAK 277 E +K EI L V+ L R L + A+ L P+ +QLQ E + L KEL+SV + Sbjct: 121 EEKKHEIHL-VQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQ 179 Query: 278 LQAQVEENELWNLLNQ-------QQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQ 330 LQA+VE N++ +LLN+ +QEE++ QEE+++EQEE++CEQE ++REQEE++ Q Sbjct: 180 LQAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQEERLCEQEERLREQEERLREQ 239 Query: 331 EEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEM 390 EE++ EQEE++RE E+++ QEE++ EQEE++REQEE++ QEE++ EQ+E+++EQEE + Sbjct: 240 EERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQEERL 299 Query: 391 WRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKL 450 QEE++REQEE ++ EQ+E++REQEE + QE+ + QE L Sbjct: 300 CEQEERLREQEE-----------RLCEQEERLREQEERLCEQEK--------LPGQERLL 340 Query: 451 REVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEE 510 EV EK+ E+E + +EQE ++R E++ E+ E+ QE+L +Q+E++W+QE Sbjct: 341 EEV-EKLLEQERRQEEQERLLER--ERLLEEVEELLEQERLRQQDERLWQQE-------- 389 Query: 511 KMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAEL 570 ++ E+++E E ++ E + EQ E++ + +LE+++ +L + Sbjct: 390 -TLQELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELKKS--- 445 Query: 571 LGGAGRESGSQRLPTLTPI 589 GGA GS+ P+ Sbjct: 446 -GGAEEPRGSESAAAARPV 463 Score = 52.8 bits (125), Expect = 1e-06 Identities = 67/310 (21%), Positives = 145/310 (46%), Gaps = 38/310 (12%) Query: 68 EMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKN 127 +++A +EN + +++ L E E+ + +E R ++ + ++ Sbjct: 179 QLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLRE----------QEERLCEQEER 228 Query: 128 SDEVKSSFKKRQEKMNEKNYTFRKRVV-IKKPWLRLGEVTAQKRPENSLLEETLHFDHAV 186 E + ++++E++ E+ R+ + + RL E + R + EE LH + Sbjct: 229 LREQEERLREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQ----EERLH-EQEE 283 Query: 187 RMGTYIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKL-RLVESEKSEIQLNVKDLK 245 R+ E+L ++ + + R +E L E+ L+E+ RL E EK Q + Sbjct: 284 RLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEKLPGQ------E 337 Query: 246 RKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEK 305 R LE + LL Q++ Q E +RL E + + +++ +E+ L +QQ+E++W Q+E Sbjct: 338 RLLEEVEKLLEQERRQEEQERL-LERERLLEEVEELLEQERL-----RQQDERLW-QQET 390 Query: 306 IQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQ 365 +QE E ++RE E + E ++EQ + R +++ + + + E++++E Sbjct: 391 LQELE--------RLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKEL 442 Query: 366 EEKMWRQEEK 375 ++ +E + Sbjct: 443 KKSGGAEEPR 452 >gi|239752551 PREDICTED: hypothetical protein [Homo sapiens] Length = 238 Score = 222 bits (566), Expect = 7e-58 Identities = 112/177 (63%), Positives = 149/177 (84%), Gaps = 5/177 (2%) Query: 309 QEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEK 368 +EE+M E+E K+RE+EE M QEEKM EQEEK+REQE+KMW QEEK++EQEEK+ EQEEK Sbjct: 3 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 62 Query: 369 MWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEK-RQEKMWRQEKKMREQDEKIREQEE 427 MW QEEK+ EQ +++ EQ+E+MW Q+E++RE+EE+ R++KMW+Q +KMR EK + QEE Sbjct: 63 MWEQEEKMWEQ-QRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMR---EKKKTQEE 118 Query: 428 EMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEK 484 +M QEEK++E EEMM +QEEK++E EEKM E+EEKM+EQEEK++ QEEK+Q QEEK Sbjct: 119 KMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEK 175 Score = 219 bits (557), Expect = 8e-57 Identities = 114/197 (57%), Positives = 153/197 (77%), Gaps = 20/197 (10%) Query: 329 RQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEE 388 R+EE+M E+E+K+RE+E+ M QEEK++EQEEK+REQEEKMW QEEK++EQ+EK+ EQEE Sbjct: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61 Query: 389 EMWRQEEKIREQEE--KRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQ 446 +MW QEEK+ EQ+ +++EKMW Q++++RE++E++REQ +MW+Q EK+R Sbjct: 62 KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQ--KMWQQVEKMR--------- 110 Query: 447 EEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMW 506 EK + EEKMQE+EEKMQEQEE + QEEK+QEQEEK W +QEEK+ EQEEKM Sbjct: 111 -EKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMW------EQEEKMREQEEKMR 163 Query: 507 RQEEKMWEQEEKMQEQE 523 QEEKM QEEKM++ E Sbjct: 164 EQEEKMQGQEEKMRDVE 180 Score = 215 bits (548), Expect = 9e-56 Identities = 108/183 (59%), Positives = 150/183 (81%), Gaps = 10/183 (5%) Query: 293 QQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQE 352 +++E+KM +EE ++EQEEKM EQE K+REQEEKMW QEEKM EQEEK+ EQE+KMW QE Sbjct: 8 REREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE 67 Query: 353 EKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQE 412 EK+ EQ +++ EQ+EKMW Q+E++RE++E+++EQ +MW+Q EK+RE+++ QE Sbjct: 68 EKMWEQ-QRLPEQKEKMWEQDERLREKEERMREQ--KMWQQVEKMREKKK-------TQE 117 Query: 413 KKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQ 472 +KM+EQ+EK++EQEE MW QEEK++E EE M +QEEK+RE EEKM+E+EEKMQ QEEK++ Sbjct: 118 EKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMR 177 Query: 473 RQE 475 E Sbjct: 178 DVE 180 Score = 209 bits (532), Expect = 6e-54 Identities = 117/217 (53%), Positives = 157/217 (72%), Gaps = 27/217 (12%) Query: 350 RQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMW 409 R+EE++RE+E+K+RE+EE M QEEK++EQ+EK++EQEE+MW QEEK++EQ +EKMW Sbjct: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQ----EEKMW 57 Query: 410 RQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEE-----EKM 464 EQ+EK+ EQEE+MW Q+ ++ E +E M +Q+E+LRE EE+M+E++ EKM Sbjct: 58 -------EQEEKMWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQKMWQQVEKM 109 Query: 465 QE----QEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQ 520 +E QEEK+Q QEEK+QEQEE W +QEEK+ EQEEKMW QEEKM EQEEKM+ Sbjct: 110 REKKKTQEEKMQEQEEKMQEQEEMMW------EQEEKMQEQEEKMWEQEEKMREQEEKMR 163 Query: 521 EQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQEL 557 EQEEKMQ QEEKMR+ E + E + QE+ Sbjct: 164 EQEEKMQGQEEKMRDVEPAGGEAGEGSPQDNPTAQEI 200 Score = 198 bits (504), Expect = 1e-50 Identities = 115/235 (48%), Positives = 159/235 (67%), Gaps = 30/235 (12%) Query: 371 RQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMW 430 R+EE++RE+++K++E+EE M QEEK++EQEEK MREQ+EK+ EQEE+M Sbjct: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEK-----------MREQEEKMWEQEEKMQ 50 Query: 431 RQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQ-- 488 QEEK+ E EE M +QEEK+ E ++++ E++EKM EQ+E+++ +EE+++EQ K W+Q Sbjct: 51 EQEEKMWEQEEKMWEQEEKMWE-QQRLPEQKEKMWEQDERLREKEERMREQ--KMWQQVE 107 Query: 489 ---EKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEE 545 EK QEEK+ EQEEKM QEE MWEQEEKMQEQEEKM QEEKMREQE ++ +QEE Sbjct: 108 KMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEE 167 Query: 546 KMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQ 600 KMQ QE +++++E GG E Q PT I+Q+ + AQ Sbjct: 168 KMQGQEEKMRDVEP-----------AGGEAGEGSPQDNPTAQEIMQLFCGMKNAQ 211 Score = 191 bits (486), Expect = 1e-48 Identities = 103/175 (58%), Positives = 133/175 (76%), Gaps = 27/175 (15%) Query: 283 EENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEK-- 340 EE E+ ++QEEKM QEEK++EQEEKM EQE K++EQEEKMW QEEKM EQEEK Sbjct: 16 EEEEMM----REQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMW 71 Query: 341 ----IREQEDKMWRQEEKIREQEEKIREQEEKMWRQ-----------EEKIREQDEKIQE 385 + EQ++KMW Q+E++RE+EE++REQ KMW+Q EEK++EQ+EK+QE Sbjct: 72 EQQRLPEQKEKMWEQDERLREKEERMREQ--KMWQQVEKMREKKKTQEEKMQEQEEKMQE 129 Query: 386 QEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELE 440 QEE MW QEEK++EQEEK MW QE+KMREQ+EK+REQEE+M QEEK+R++E Sbjct: 130 QEEMMWEQEEKMQEQEEK----MWEQEEKMREQEEKMREQEEKMQGQEEKMRDVE 180 Score = 169 bits (428), Expect = 7e-42 Identities = 94/192 (48%), Positives = 139/192 (72%), Gaps = 18/192 (9%) Query: 241 VKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLN--QQQEEK 298 +++ +R ER + + ++++ E + +++Q K++ Q E ++W Q+QEEK Sbjct: 1 MREEERMREREKKMREEEEMMREQE---EKMQEQEEKMREQ--EEKMWEQEEKMQEQEEK 55 Query: 299 MWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIRE- 357 MW QEEK+ EQEEKM EQ+ ++ EQ+EKMW Q+E++ E+EE++REQ KMW+Q EK+RE Sbjct: 56 MWEQEEKMWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQ--KMWQQVEKMREK 112 Query: 358 ---QEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKK 414 QEEK++EQEEKM QEE + EQ+EK+QEQEE+MW QEEK+REQEEK +E QE+K Sbjct: 113 KKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMRE----QEEK 168 Query: 415 MREQDEKIREQE 426 M+ Q+EK+R+ E Sbjct: 169 MQGQEEKMRDVE 180 Score = 145 bits (365), Expect = 1e-34 Identities = 80/184 (43%), Positives = 125/184 (67%), Gaps = 21/184 (11%) Query: 234 KSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSV-SAKLQAQVEENELWNLLN 292 + E ++ ++ K + E + ++++Q + +++ ++ + + + + Q +E ++W Sbjct: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMW---- 57 Query: 293 QQQEEKMWRQEEK------IQEQEEKMCEQELKIREQEE-----KMWRQEEKMHE----Q 337 +QEEKMW QEEK + EQ+EKM EQ+ ++RE+EE KMW+Q EKM E Q Sbjct: 58 -EQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQ 116 Query: 338 EEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKI 397 EEK++EQE+KM QEE + EQEEK++EQEEKMW QEEK+REQ+EK++EQEE+M QEEK+ Sbjct: 117 EEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKM 176 Query: 398 REQE 401 R+ E Sbjct: 177 RDVE 180 Score = 111 bits (278), Expect = 2e-24 Identities = 68/144 (47%), Positives = 94/144 (65%), Gaps = 23/144 (15%) Query: 473 RQEEKIQEQEEKTWRQEKLLK-QEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEE 531 R+EE+++E+E+K +E++++ QEEK+ EQEEKM QEEKMWEQEEKMQEQEEKM QEE Sbjct: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61 Query: 532 KMREQEVRLWQQE------EKMQEQEVRLQELEERL--GKLGQKAELLGGAGRESGSQRL 583 KM EQE ++W+Q+ EKM EQ+ RL+E EER+ K+ Q+ E + RE + Sbjct: 62 KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKM----REKKKTQ- 116 Query: 584 PTLTPILQVELKSQEAQSLQQQQD 607 E K QE + Q+Q+ Sbjct: 117 ---------EEKMQEQEEKMQEQE 131 Score = 100 bits (250), Expect = 3e-21 Identities = 57/129 (44%), Positives = 83/129 (64%), Gaps = 4/129 (3%) Query: 478 IQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQE 537 ++E+E R++K+ ++EE + EQEEKM QEEKM EQEEKM EQEEKMQ QEEKM EQE Sbjct: 1 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60 Query: 538 VRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQ 597 ++W+QEEKM EQ Q L E+ K+ ++ E L Q++ ++ + K+Q Sbjct: 61 EKMWEQEEKMWEQ----QRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQ 116 Query: 598 EAQSLQQQQ 606 E + +Q++ Sbjct: 117 EEKMQEQEE 125 Score = 95.5 bits (236), Expect = 1e-19 Identities = 61/182 (33%), Positives = 102/182 (56%), Gaps = 5/182 (2%) Query: 164 EVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEELKEKNAEL 223 E ++R + EE + + +M EK+ ++ + +++ +E +EK E Sbjct: 4 EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEE----KMWEQEEKMQEQEEKMWEQ 59 Query: 224 QEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVE 283 +EK+ + EK Q + + K K+ L +++ ++ ++ ++++ + K + Q E Sbjct: 60 EEKM-WEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEE 118 Query: 284 ENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIRE 343 + + Q+QEE MW QEEK+QEQEEKM EQE K+REQEEKM QEEKM QEEK+R+ Sbjct: 119 KMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRD 178 Query: 344 QE 345 E Sbjct: 179 VE 180 >gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo sapiens] Length = 479 Score = 183 bits (464), Expect = 5e-46 Identities = 116/296 (39%), Positives = 191/296 (64%), Gaps = 33/296 (11%) Query: 231 ESEKSEIQLNVKDLKRKL-----ERAQLLLPQ--------QQLQVEADRLGKELQSVSAK 277 E +K EI L V+ L R L + A+ L P+ +QLQ E + L KEL+SV + Sbjct: 121 EEKKHEIHL-VQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQ 179 Query: 278 LQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQ 337 LQA+VE N++ +LLN++QEE++ QEE++ EQEE++ EQE ++ EQEE++ QEE++ EQ Sbjct: 180 LQAEVENNQMLSLLNRRQEERLREQEERLHEQEERLHEQEERLCEQEERLCEQEERLREQ 239 Query: 338 EEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQE-----EKIREQDEKIQEQEEEMWR 392 EE++REQE+++ QEE++ EQEE++ EQEE++ QE E++ E+ EK+ EQE R Sbjct: 240 EERLREQEERLHEQEERLCEQEERLCEQEERLCEQEKLPGQERLLEEVEKLLEQER---R 296 Query: 393 QEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQE-----EKIRELEEMMQDQE 447 QEE+ R E +E++ + +++ EQ E++R+Q+E +W+QE E++RELE + + Sbjct: 297 QEEQERLLE---RERLLDEVEELLEQ-ERLRQQDERLWQQETLRELERLRELERLR--EL 350 Query: 448 EKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEE 503 E+LRE+E ++ E + EQ + + E++ + + T + E+ +K+ EK EE Sbjct: 351 ERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELEKSGGAEE 406 Score = 143 bits (361), Expect = 4e-34 Identities = 97/271 (35%), Positives = 162/271 (59%), Gaps = 26/271 (9%) Query: 330 QEEKMHEQEEKIREQEDKMWRQEEKIREQE-EKIREQEEKMWRQEEKIREQDEKIQEQEE 388 +EEK HE K+ R K++ Q E + + + E+++++ ++++ E Sbjct: 120 KEEKKHEIH-----LVQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELE 174 Query: 389 EMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEE 448 + RQ + E + RQE+++REQ+E++ EQEE + QEE++ E EE + +QEE Sbjct: 175 SVGRQLQAEVENNQMLSLLNRRQEERLREQEERLHEQEERLHEQEERLCEQEERLCEQEE 234 Query: 449 KLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQE------EKIWEQE 502 +LRE EE+++E+EE++ EQEE++ QEE++ EQEE+ QEKL QE EK+ EQE Sbjct: 235 RLREQEERLREQEERLHEQEERLCEQEERLCEQEERLCEQEKLPGQERLLEEVEKLLEQE 294 Query: 503 EKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQE-----EKMQEQEVRLQEL 557 + ++E++ E+E + E EE ++ +E++R+Q+ RLWQQE E+++E E RL+EL Sbjct: 295 RRQ-EEQERLLERERLLDEVEELLE--QERLRQQDERLWQQETLRELERLRELE-RLREL 350 Query: 558 E-----ERLGKLGQKAELLGGAGRESGSQRL 583 E ER+ +LG +A A SG + L Sbjct: 351 ERLRELERMLELGWEALYEQRAEPRSGFEEL 381 Score = 50.8 bits (120), Expect = 4e-06 Identities = 46/189 (24%), Positives = 102/189 (53%), Gaps = 11/189 (5%) Query: 215 ELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKL-ERAQLLLPQQQLQVEADRL-GKE-- 270 E +E+ E +E+LR E E + + + + +L E+ + L Q++ E ++L G+E Sbjct: 224 EQEERLCEQEERLREQEERLREQEERLHEQEERLCEQEERLCEQEERLCEQEKLPGQERL 283 Query: 271 LQSVSAKLQAQVEENELWNLLNQQQ---EEKMWRQEEKIQEQEEKMCEQELKIREQEEKM 327 L+ V L+ + + E LL +++ E + ++E++++Q+E++ +QE +RE E Sbjct: 284 LEEVEKLLEQERRQEEQERLLERERLLDEVEELLEQERLRQQDERLWQQE-TLRELER-- 340 Query: 328 WRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQE 387 R+ E++ E E++RE E + E + EQ + R E++ + + + +++++E E Sbjct: 341 LRELERLREL-ERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELE 399 Query: 388 EEMWRQEEK 396 + +E + Sbjct: 400 KSGGAEEPR 408 >gi|148746195 trichohyalin [Homo sapiens] Length = 1943 Score = 180 bits (457), Expect = 3e-45 Identities = 142/557 (25%), Positives = 298/557 (53%), Gaps = 58/557 (10%) Query: 40 EQQSKVRNKGHGKPREKSIADEKFFQL-SEMEA-----YLENRKRRGTKRWDEDDDLEES 93 EQ+ + + R KS + +QL SE +A Y RK+ G +R E ++ Sbjct: 682 EQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRR 741 Query: 94 EDSKQCKESLKRVTFTLPDDEAIED---AGVSHVKKNSDEVKSSFKKRQEKMNEKNYTFR 150 +S+ + +R ++E D + K + S + + E+ Sbjct: 742 RESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAE 801 Query: 151 KRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDAPSLELYRNT 210 +R ++ +L E Q+R + E+ L F E+L + A L+ + Sbjct: 802 ERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEE------EQLQRRERAQQLQEEEDG 855 Query: 211 ITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKE 270 + +++ + ++ E + +K QL + + R L + LQ + + + Sbjct: 856 LQEDQERRRSQEQRR------DQKWRWQLE----EERKRRRHTLYAKPALQEQLRKEQQL 905 Query: 271 LQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMC--EQELKIREQEEKMW 328 LQ +LQ + E +Q++E+ +R+EE++Q++EE++ E+E + R++ E+ + Sbjct: 906 LQEEEEELQREEREKR-----RRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQY 960 Query: 329 RQEEKMHEQEEKIREQEDKMWRQEE---KIREQEEKIREQEEKMWRQEEKIREQDEKIQE 385 R+++K+ ++EE++ +E + R++E K RE+EE +E+E+ + + EK R Q+ + Q Sbjct: 961 RKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQY 1020 Query: 386 QEEEMWRQEEK--IREQEEKR----QEKMWRQEKKMREQDEKIREQEEEMWRQEE---KI 436 ++++ +QEE+ +RE+ EKR +E+ +R+E+++++++E++ +E E R++E + Sbjct: 1021 RKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQY 1080 Query: 437 RELEEMMQDQEEKLREVEEK--MQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQ--EKLL 492 R+ EE+ Q++E+ LRE EK QE E + +E+EE Q +E+ ++E+ EK RQ E+ Sbjct: 1081 RKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQY 1140 Query: 493 KQEEKIWEQEEKMWRQE---------EKMWEQEEKMQEQEEKMQRQE-EKMREQEVRLWQ 542 ++EE++ ++EE++ R+E E+ + +EE++Q++EE++ R+E EK R++ R ++ Sbjct: 1141 REEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYR 1200 Query: 543 QEEKMQEQEVRLQELEE 559 +EE++Q Q+ + + +E Sbjct: 1201 EEEELQRQKRKQRYRDE 1217 Score = 177 bits (450), Expect = 2e-44 Identities = 161/579 (27%), Positives = 297/579 (51%), Gaps = 82/579 (14%) Query: 60 DEKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDE---AI 116 D++ F+ + + E +RR KR +++ +L E E+ + +E L++ D+E Sbjct: 118 DQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQR 177 Query: 117 EDAGVSHVKKNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLL 176 ++ ++ +E S K + + R+R +++ E Q+R Sbjct: 178 QEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQ--- 234 Query: 177 EETLHFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSE 236 +++ +E + + EE K + E Q + L E E+ Sbjct: 235 ----------------DRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQ- 277 Query: 237 IQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQE 296 RKLER +L +Q+ + + RL +E Q L+ + EE +QQE Sbjct: 278 --------LRKLERQELRRERQEEEQQQQRLRREQQ-----LRRKQEEER-----REQQE 319 Query: 297 EKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQ----EDKMWRQE 352 E+ R++++ +EQ+E+ EQ+L+ REQEE+ R+++ EQEE+ REQ E + R+E Sbjct: 320 ER--REQQERREQQEERREQQLR-REQEER--REQQLRREQEEERREQQLRREQEEERRE 374 Query: 353 EKIREQEEKIREQE---EKMWRQEEKIREQDEKIQEQ----EEEMWRQEEKIREQEEKRQ 405 +++R +++ REQ+ E+ R+E+++R + + +EQ E+++ R+++ REQEE+R Sbjct: 375 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERH 434 Query: 406 EKMWRQEKK----MREQDEK----IREQEEEMWRQEEKIRELEEMMQDQEE-------KL 450 E+ QE++ REQ+E+ RE+E E QE R +++ +DQEE KL Sbjct: 435 EQKHEQERREQRLKREQEERRDWLKREEETERHEQE---RRKQQLKRDQEEERRERWLKL 491 Query: 451 REVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEE 510 E E + Q+E + Q + E+ +R+E++++ QEE+ Q++L +++ EQEE R+E+ Sbjct: 492 EEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEE---RREQ 548 Query: 511 KMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAEL 570 + +EEK EQE + QR + + E+ +L ++EE+ ++Q ++ +E EERL + ++ E+ Sbjct: 549 LLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLK-REQEERLEQRLKREEV 607 Query: 571 LGGAGRESGSQRLPTLTP---ILQVELKSQEAQSLQQQQ 606 E QRL P Q LKS+E + +QQQ Sbjct: 608 ERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQ 646 Score = 176 bits (446), Expect = 6e-44 Identities = 152/567 (26%), Positives = 299/567 (52%), Gaps = 78/567 (13%) Query: 74 ENRKRRGTKRWDEDDDLEESEDSK-QCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVK 132 E + RG +R L E + + + +E +R LP++E E Sbjct: 774 EEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQ-------------- 819 Query: 133 SSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAV---RMG 189 ++RQ + EK F + ++ L+ E Q + E L+E + R Sbjct: 820 ---RRRQRREREKELQFLE----EEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQ 872 Query: 190 TYIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLE 249 + +L +ER LY E+L+++ LQE E+ E+Q ++ +R+ E Sbjct: 873 KWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQE-------EEEELQREEREKRRRQE 925 Query: 250 RAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQ 309 + + ++QLQ E ++L +E + + Q+ E+ +R+++K+Q++ Sbjct: 926 QERQYREEEQLQQEEEQLLREEREKRRR----------------QERERQYRKDKKLQQK 969 Query: 310 EEKMC--EQELKIREQEEKMWRQEEKMHEQEEKI-REQEDKMWRQE-EKIREQEEKIREQ 365 EE++ E E + R++ EK +R+EE++ ++EE++ RE+ +K RQE E+ ++++++++ Sbjct: 970 EEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQE 1029 Query: 366 EEKMWRQE-EKIREQDEKIQEQEEEMWRQEEK--IREQEEKRQ----EKMWRQEKKMREQ 418 EE++ R+E EK R Q+ + Q +EEE +QEE+ + E+ E R+ E+ +R+E++++++ Sbjct: 1030 EEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQE 1089 Query: 419 DEKIREQEEEMWRQEEK---IRELEEMMQDQEEKLREVEEKMQEEE-EKMQEQEEKIQRQ 474 +E++ +E E R++E+ RE EE+ Q++E+ LRE EK + +E E+ +EE++Q++ Sbjct: 1090 EEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQE 1149 Query: 475 EEKI-QEQEEKTWRQE---------KLLKQEEKIWEQEEKMWRQE-EKMWEQEEKMQEQE 523 EE++ +E+ EK RQE +L ++EE++ +E++ RQE E+ + +EE++Q Q+ Sbjct: 1150 EEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQK 1209 Query: 524 EKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQR- 582 K + ++E R W+ E +E VR ++ + + Q +L R+ SQ+ Sbjct: 1210 RKQRYRDEDQRSDLKWQWEPE---KENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQD 1266 Query: 583 LPTLTPILQVELKSQEAQSLQQQQDHY 609 L L Q + QE + QQ+ H+ Sbjct: 1267 LQHLLGEQQERDREQERRRWQQRDRHF 1293 Score = 174 bits (441), Expect = 2e-43 Identities = 165/650 (25%), Positives = 332/650 (51%), Gaps = 91/650 (14%) Query: 40 EQQSKVRNKGHGKPREKSIADEKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQC 99 E+ + R K K ++ E++ +L E E + +R R ++++ E+ ++ Sbjct: 465 ERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEE 524 Query: 100 KESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPW 159 +E L++ + ++ + K +E + ++R++++ + R +++ ++ Sbjct: 525 EERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEE 584 Query: 160 LRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTK-ERDAPSLELYRNTITDEELKE 218 R + KR + LE+ L + R+ + + +R+ P E + + EE +E Sbjct: 585 RRQQRL---KREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEE 641 Query: 219 ------------------KNAELQEKL-----RLVESEKSEIQLNVKDLKRKLERAQLLL 255 K E +E+L R E E+ E +L ++ ++ ER + + Sbjct: 642 RRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRI 701 Query: 256 P--QQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKM 313 P Q QL+ EAD ++ S K + Q Q+QEEK R+E ++Q QEE+ Sbjct: 702 PKWQWQLESEADARQSKVYSRPRKQEGQRRR--------QEQEEKRRRRESELQWQEEER 753 Query: 314 CEQELKIREQEEKM---WRQEEKMHEQEEKI------REQEDKMWRQEEKIREQEEKIRE 364 ++ + EQ W+ EEK +++ REQ ++ R EE+ + ++ + E Sbjct: 754 AHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPE 813 Query: 365 QEEKMWRQEEKIREQDEKIQ--EQEEEMWRQE--EKIREQEEKRQEKMWRQEKKMREQDE 420 +EEK R+ ++ RE+++++Q E+EE++ R+E ++++E+E+ QE R+ + + +D+ Sbjct: 814 EEEKEQRRRQR-REREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQ 872 Query: 421 KIREQ-EEEMWRQ----------EEKIRELEEMMQDQEEKL---------REVEEKMQEE 460 K R Q EEE R+ +E++R+ ++++Q++EE+L R+ +E+ E Sbjct: 873 KWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYRE 932 Query: 461 EEKMQEQEEKIQRQE-EKIQEQE-EKTWRQEKLLKQEEK--IWEQEEKMWRQE--EKMWE 514 EE++Q++EE++ R+E EK + QE E+ +R++K L+Q+E+ + E+ EK RQE +K E Sbjct: 933 EEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYRE 992 Query: 515 QEEKMQEQEEKMQRQEEKMREQE-VRLWQQEEKMQEQEV----------RLQELEERL-- 561 +EE QE+E+ ++ + EK R QE R +++++++Q++E RLQE E + Sbjct: 993 EEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYRE 1052 Query: 562 -GKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYR 610 +L Q+ E L G RE+ ++ + EL+ +E Q L+++ + R Sbjct: 1053 EEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRR 1102 Score = 173 bits (438), Expect = 5e-43 Identities = 166/652 (25%), Positives = 340/652 (52%), Gaps = 95/652 (14%) Query: 38 KLEQQSKVRNKGHGKPREKSIADEKFFQLSEMEAYLE--NRKRRGTKRWDEDDDLEESED 95 +LE++ R + + +E+ +A+ + + SE + LE +R+RR + W + + +E E+ Sbjct: 128 QLEEEPGQRRRQKRQEQERELAEGE--EQSEKQERLEQRDRQRRDEELWRQRQEWQEREE 185 Query: 96 SKQCKESLKRV----TFTLPDDEAIEDAGVSHVK-KNSDEVKSSFKKRQEKM--NEKNYT 148 + +E L+ T PD+E + + ++ K +E + ++RQ+++ E+ Sbjct: 186 RRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKE 245 Query: 149 FRKR-VVIKKPWLRLGEVTAQKRPENSLLEETLHF--DHAVRMGTYIEKLTKERDAPSLE 205 +RKR V++K +L E Q++ E EE L +R E+ ++R + Sbjct: 246 WRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQ 305 Query: 206 LYRNTITDEELKEKNAELQEKLRLVESEKSEIQLN-------VKDLKRKLE---RAQLLL 255 L R + +++ Q++ R + E+ E QL + L+R+ E R Q L Sbjct: 306 LRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLR 365 Query: 256 PQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCE 315 +Q+ + +L +E Q + + Q+ + Q + E+ R+E++++ +++ E Sbjct: 366 REQEEERREQQLRREQQ---LRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 422 Query: 316 QELKIREQEEKMWRQEEKMHEQEEKI-REQEDKM-W--------RQEEKIREQEEKIREQ 365 Q+L+ REQEE+ Q+ + +E+++ REQE++ W R E++ R+Q+ K ++ Sbjct: 423 QQLR-REQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQE 481 Query: 366 EEKMWR----QEEKIREQDEKIQEQ---------EEEMWRQEEK-------------IRE 399 EE+ R +EE+ REQ E+ ++Q E+ + RQEE+ RE Sbjct: 482 EERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRRE 541 Query: 400 QEEKRQEKMWRQEKKMREQDEK----IREQEE---EMWRQEEKIRELEEMMQDQEEKLRE 452 QEE+R++ + R+E+K EQ+ + REQEE ++ ++EE+ R+ + + ++QEE+L Sbjct: 542 QEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQ-QRLKREQEERL-- 598 Query: 453 VEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKM 512 E++++ EE + EQEE R+E++++ +E + R+++LLK EE+ +++++ R++++ Sbjct: 599 -EQRLKREEVERLEQEE---RREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQER 654 Query: 513 WEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKL-------- 564 EQ K +E+EE+++++ ++ E+E R +QE +EQE + ++ R+ K Sbjct: 655 REQRLKREEEEERLEQRLKREHEEERR--EQELAEEEQEQARERIKSRIPKWQWQLESEA 712 Query: 565 -GQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQQ 615 +++++ ++ G +R + E K + +S Q Q+ R H QQ Sbjct: 713 DARQSKVYSRPRKQEGQRRRQ------EQEEKRRRRESELQWQEEERAHRQQ 758 Score = 171 bits (434), Expect = 1e-42 Identities = 156/533 (29%), Positives = 298/533 (55%), Gaps = 77/533 (14%) Query: 129 DEVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRM 188 D +S + R+++ +++ + R R + ++P G+ QKR E E + Sbjct: 104 DGKESLLQDRRQEEDQRRFEPRDRQLEEEP----GQRRRQKRQEQE--RELAEGEEQSEK 157 Query: 189 GTYIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRK- 247 +E+ ++R EL+R +E +E+ AE +E+L+ + ++E + + L+R+ Sbjct: 158 QERLEQ--RDRQRRDEELWRQRQEWQEREERRAE-EEQLQSCKGHETEEFPDEEQLRRRE 214 Query: 248 ---LERAQLLLPQQQLQVEADRLGKE--------LQSVSAKLQAQVEENELWNLLNQQQE 296 L R QQQ + DR+ +E ++V K + +++E E Q+E Sbjct: 215 LLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEE 274 Query: 297 E----KMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQE 352 E K+ RQE + + QEE+ +Q+ ++R +++ +QEE+ EQ+E+ REQ+++ +QE Sbjct: 275 EEQLRKLERQELRRERQEEE--QQQQRLRREQQLRRKQEEERREQQEERREQQERREQQE 332 Query: 353 EKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQ----EEEMWRQEEKIREQEEKRQEKM 408 E+ REQ+ + REQEE+ R+++ REQ+E+ +EQ E+E R+E+++R +++ R+E+ Sbjct: 333 ER-REQQLR-REQEER--REQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQ 388 Query: 409 WRQEKKMREQDEKIREQE---EEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKM- 464 R+E+++R + + REQ+ E+ R+E+++R +++ ++QEE+ E + + + E+++ Sbjct: 389 LRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLK 448 Query: 465 QEQEEK---IQRQEEKIQEQEEK----------TWRQEKLLK-QEEKIWEQEEK----MW 506 +EQEE+ ++R+EE + ++E+ R+E+ LK +EE+ EQ+E+ + Sbjct: 449 REQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLR 508 Query: 507 RQEEKMWEQEEKMQEQEEKMQR----QEEKMREQEVR----LWQQEEKMQEQEVRLQEL- 557 R++E+ EQ K QE+EE++Q+ +++ REQE R L ++EEK EQE R Q L Sbjct: 509 REQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLK 568 Query: 558 ---EERLGKLGQKAELLGGAGRESGSQRLP-TLTPILQVELKSQEAQSLQQQQ 606 EER +L ++ E E QRL L+ LK +E + L+Q++ Sbjct: 569 REQEERRDQLLKREE-------ERRQQRLKREQEERLEQRLKREEVERLEQEE 614 Score = 171 bits (432), Expect = 3e-42 Identities = 154/571 (26%), Positives = 296/571 (51%), Gaps = 82/571 (14%) Query: 40 EQQSKVRNKGHGKPREKSIADEKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQC 99 E++ K + + + REK + Q E E L+ R+ R + +E+D L+E ++ ++ Sbjct: 813 EEEEKEQRRRQRREREKEL------QFLEEEEQLQ-RRERAQQLQEEEDGLQEDQERRRS 865 Query: 100 KESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPW 159 +E + + +E E H ++ +K Q+ + E+ ++ K+ Sbjct: 866 QEQRRDQKWRWQLEE--ERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKR-- 921 Query: 160 LRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEELKEK 219 R E Q R E L +E + +R E+ K R YR D++L++K Sbjct: 922 -RRQEQERQYREEEQLQQEE---EQLLR-----EEREKRRRQERERQYRK---DKKLQQK 969 Query: 220 NAEL----QEKLRLVESEKS-----EIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKE 270 +L EK R E EK E+Q + L R+ + ++ + D L +E Sbjct: 970 EEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQE 1029 Query: 271 LQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMC--EQELKIREQEEKMW 328 + + L+ + E+ L Q+ E+ +R+EE++Q++EE++ E+E + R++ E+ + Sbjct: 1030 EEQL---LREEREKRRL------QERERQYREEEELQQEEEQLLGEERETRRRQELERQY 1080 Query: 329 RQEEKMHEQEEKI-REQEDKMWRQEEK--IREQEEKIREQEEKMWRQEEKIREQDEKIQE 385 R+EE++ ++EE++ RE+ +K RQE + RE+EE +E+E+ + + EK R Q+ + Q Sbjct: 1081 RKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQY 1140 Query: 386 QEEEMWRQEEK--IREQEEKRQ----EKMWRQEKKMREQDEKIREQEEEMWRQE-EKIRE 438 +EEE +QEE+ +RE+ EKR+ E+ +R+E+++++++E++ +E+E RQE E+ Sbjct: 1141 REEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYR 1200 Query: 439 LEEMMQDQEEKLREVEE------KMQEEEEKM------------QEQEEKIQRQEEKIQE 480 EE +Q Q+ K R +E K Q E EK +E E+ Q ++ ++++ Sbjct: 1201 EEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRD 1260 Query: 481 QEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEK------MQRQEEKM- 533 ++ + Q L +Q+E+ EQE + W+Q ++ + +EE+++ +E+K + QEEK Sbjct: 1261 RQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQL 1320 Query: 534 ----REQEVRLWQQEEKMQEQEVRLQELEER 560 RE++ R + + K +E+E LQE EE+ Sbjct: 1321 LREEREEKRRRQETDRKFREEEQLLQEREEQ 1351 Score = 167 bits (422), Expect = 4e-41 Identities = 166/682 (24%), Positives = 327/682 (47%), Gaps = 135/682 (19%) Query: 48 KGHGKPREKSIADEKFFQLSEMEAYLENRKRRGTKRWDED----DDLEESEDS----KQC 99 K + REK +E+ Q E + E R++R + W+ D+L++ E+ ++ Sbjct: 980 KRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREERE 1039 Query: 100 KESLKRVTFTLPDDEAIEDA-----GVSHVKKNSDEVKSSFKKRQEKMNEKNYTFRKRVV 154 K L+ ++E ++ G + E++ ++K +E E+ R+ Sbjct: 1040 KRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPE 1099 Query: 155 IKKPWLRLGEVTAQKRPENSLLEET---LHFDHAVRMGTYIEKLTKERDAPSLELYRNTI 211 + R E Q R E L +E L + R +E+ +E + E + Sbjct: 1100 KR----RRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQE-EEQLL 1154 Query: 212 TDEELKEKNAELQEKLRLVES--EKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRL-- 267 +E K + EL+ + R E ++ E L + KR+ ER + +++LQ + + Sbjct: 1155 REEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRY 1214 Query: 268 -----------------------------GKE----LQSVSAKLQAQVEENELWNLLNQQ 294 G+E Q ++L+ + + +L +LL +Q Sbjct: 1215 RDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQ 1274 Query: 295 QEE------KMWRQ-------EEKIQEQEEKMC---------EQELKIREQEEKMWRQE- 331 QE + W+Q EE+++ +E+K E++L E+EEK RQE Sbjct: 1275 QERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQET 1334 Query: 332 -EKMHEQEEKIREQEDKMWRQEE---KIREQEEKIREQEEKMWRQEEKIREQDEKIQEQE 387 K E+E+ ++E+E++ R++E K RE+E + +EQ K +E+++R QE+E Sbjct: 1335 DRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRR-----QERE 1389 Query: 388 EEMWRQEEKIREQEEKRQ-----EKMWRQEKKM---REQDEKIREQEEEMWRQEEKIREL 439 + ++E+++R QE ++Q ++ +R+E++ +E+D K RE+E+++ RQE + + L Sbjct: 1390 RKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFL 1449 Query: 440 EE---MMQDQEEKLREVEEKMQEEEEKM---QEQEEKIQRQEEKIQEQE-EKTWRQEKLL 492 EE + Q++ K RE E+ +QE EE+ QE++ K +E++++ QE ++ +R+++L Sbjct: 1450 EEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELR 1509 Query: 493 KQ--EEKIWEQEEKMWRQ--EEKMWEQEEKMQEQEEKMQRQEE---KMREQEVRLWQQEE 545 Q E K E+E+++ RQ + K ++E++++ QE QR+++ K RE+E ++EE Sbjct: 1510 SQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREE 1569 Query: 546 ------------KMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVE 593 +++EQ+VR QE E + + Q+ R+ G Q+L + + Sbjct: 1570 QQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLR------RQEGQQQLRQ-----ERD 1618 Query: 594 LKSQEAQSLQQQQDHYRGHLQQ 615 K +E + L Q+++ + H Q+ Sbjct: 1619 RKFREDEQLLQEREEQQLHRQE 1640 Score = 164 bits (415), Expect = 2e-40 Identities = 163/671 (24%), Positives = 319/671 (47%), Gaps = 104/671 (15%) Query: 18 DPTKSPVLSDEDSDLDFHINKLEQQSKVRNKGHGKPREKSIADEKFFQLSEMEAYLENRK 77 +P + L +E+ L KLE+Q R + + +++ + E+ + + E E ++ Sbjct: 264 EPQRQRELQEEEEQL----RKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQE 319 Query: 78 RRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSFKK 137 R ++ + E E + ++ +R + E E+ +++ +E + + Sbjct: 320 ERREQQERREQQEERREQQLRREQEERREQQLRREQE--EERREQQLRREQEEERREQQL 377 Query: 138 RQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTK 197 R+E+ + R+ +++ +L +R + E+ L + +R + + Sbjct: 378 RREQQLRREQQLRREQQLRREQ-QLRREQQLRREQQLRREQQLRREQQLR-----REQEE 431 Query: 198 ERDAPSLELYRNTITDEELKEKNAELQEKL-RLVESEKSEIQLNVKDLKRKLERAQLLLP 256 ER E R ++ LK + E ++ L R E+E+ E + + LKR E + Sbjct: 432 ERHEQKHEQERR---EQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERR--- 485 Query: 257 QQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMW---RQEEKIQEQEEKM 313 ++ L++E + ++ + +L+ + EE L Q++EE++ R E++++ ++E+ Sbjct: 486 ERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEER 545 Query: 314 CEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWR-- 371 EQ LK +EEK QE + + + E+ D++ ++EE+ R+Q K REQEE++ + Sbjct: 546 REQLLK--REEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLK-REQEERLEQRL 602 Query: 372 --------QEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIR 423 ++E+ REQ K +E EEE +Q K EQEE+RQ+++ R++++ REQ K Sbjct: 603 KREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKRE 662 Query: 424 EQEEEMW----RQEEKIRELEEMMQDQEEKLRE-------------------------VE 454 E+EE + R+ E+ R +E+ ++++E+ RE Sbjct: 663 EEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSR 722 Query: 455 EKMQEEEEKMQEQEEKIQRQEEKIQEQEEK---------------TWRQEKLLKQEE--- 496 + QE + + QEQEEK +R+E ++Q QEE+ TW+ + K E Sbjct: 723 PRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQ 782 Query: 497 ------KIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKM-REQEVRLWQQEEKMQE 549 + EQ E+ R EE+ ++ + E+EEK QR+ ++ RE+E++ ++EE++Q Sbjct: 783 RLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQR 842 Query: 550 QEVRLQELEERLGKLGQKAELLGGAGR-----------ESGSQRLPTL--TPILQVELKS 596 +E R Q+L+E L + E + E +R TL P LQ +L+ Sbjct: 843 RE-RAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLR- 900 Query: 597 QEAQSLQQQQD 607 +E Q LQ++++ Sbjct: 901 KEQQLLQEEEE 911 Score = 161 bits (407), Expect = 2e-39 Identities = 157/679 (23%), Positives = 315/679 (46%), Gaps = 117/679 (17%) Query: 19 PTKSPVLSDEDSDLDFHINKLEQQSKVRNKGHGKPREKSIADEKFFQLSEMEAYLENRKR 78 P + + +E + K +++ ++ + + R + D KF E E L+ R+ Sbjct: 1294 PEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKF---REEEQLLQEREE 1350 Query: 79 RGTKRWDED-----DDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKS 133 + +R + D ++L E ++ E +R+ + + +++ ++ +++ Sbjct: 1351 QPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQ 1410 Query: 134 SFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIE 193 R K E+ ++ +K +V Q+R L EE R E Sbjct: 1411 D---RDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEE 1467 Query: 194 KLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKS--EIQLNVKDLKRKLERA 251 +L +ER+ L +E K E +++LR E ++ E +L ++ +RK Sbjct: 1468 QLLQEREEQQLHR-------QERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEE 1520 Query: 252 QLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEE 311 + L +QQ Q ++ +L+ Q + +Q ++ +R+EE+++++ E Sbjct: 1521 EQQLHRQQRQ-------RKFLQEEQQLRRQERGQQ-----RRQDRDRKFREEEQLRQERE 1568 Query: 312 KMCEQELKIREQEEKMWRQEEKMH--EQEEKIREQEDKMWRQE----------EKIREQE 359 EQ+L +E++ K +E+K+ EQE K E E ++ RQE K RE E Sbjct: 1569 ---EQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDE 1625 Query: 360 EKIREQEEKMWRQEE---------------------------KIREQDEKIQEQEEEMWR 392 + ++E+EE+ ++E K RE+++ +QE EE+ R Sbjct: 1626 QLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLR 1685 Query: 393 QEEKIRE-QEEKRQEKMWRQEKKMREQDEKIREQE-EEMWRQEEKIR-ELEEMMQDQEEK 449 ++E+ R+ +EE++Q + +E+K ++++++R QE E +R+EE++R E E+ ++E+ Sbjct: 1686 RQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQER 1745 Query: 450 LREVEEKMQ------EEEEKMQEQEEKIQRQEEKIQEQEEKTWRQE----KLLKQEEKIW 499 R++ E+ Q E++ + QE++ K + +E+ QE+EE+ R + K ++E+ Sbjct: 1746 YRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQ 1805 Query: 500 EQEEKMWRQEEK----MWEQEEKMQEQEEKMQRQE--------------EKMREQEVRLW 541 E+EE+ R +++ WE+E+ E++E+ RQE EK R +E LW Sbjct: 1806 EREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELW 1865 Query: 542 QQEE---------KMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQV 592 Q+EE K++E+ +R Q+ EE+ + Q E+ G+ G P V Sbjct: 1866 QEEEQKRRQERERKLREEHIRRQQKEEQRHR--QVGEIKSQEGKGHGRLLEPGTHQFASV 1923 Query: 593 ELKSQEA-QSLQQQQDHYR 610 ++S + +Q+Q+ YR Sbjct: 1924 PVRSSPLYEYIQEQRSQYR 1942 Score = 151 bits (381), Expect = 2e-36 Identities = 128/459 (27%), Positives = 259/459 (56%), Gaps = 59/459 (12%) Query: 217 KEKNAELQEKLRLVESEKSEI-QLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVS 275 +EK A K L++ + E Q + R+LE +Q+ Q E +R E + S Sbjct: 97 EEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQ-EQERELAEGEEQS 155 Query: 276 AKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQEL--KIREQEEKMWRQEEK 333 K Q ++E+ + Q+++E++WRQ ++ QE+EE+ E+E + E + + EE+ Sbjct: 156 EK-QERLEQRD-----RQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQ 209 Query: 334 MHEQE-----EKIRE--QEDKMWRQEEKIREQEEK-IREQEEKMWRQEEKIREQD----E 381 + +E K RE Q+ + RQ+ +E+EEK R++E + ++EEK++E++ Sbjct: 210 LRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQR 269 Query: 382 KIQEQEEEMWRQE----EKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIR 437 ++QE+EE++ + E + R++EE++Q+++ R+++ R+Q+E+ REQ+EE Q+E+ Sbjct: 270 ELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERRE 329 Query: 438 ELEE-----------------MMQDQEEKLREVEEKMQEEEEKMQEQ---EEKIQRQEEK 477 + EE + ++QEE+ RE + + ++EEE+ ++Q E++++R+++ Sbjct: 330 QQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQL 389 Query: 478 IQEQE---EKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKM- 533 +EQ+ E+ R+E+ L++E+++ +E+++ R+++ EQEE+ EQ+ + +R+E+++ Sbjct: 390 RREQQLRREQQLRREQQLRREQQL-RREQQLRREQQLRREQEEERHEQKHEQERREQRLK 448 Query: 534 REQEVRL-W---QQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPI 589 REQE R W ++E + EQE R Q+L+ + ++ E E ++ Sbjct: 449 REQEERRDWLKREEETERHEQERRKQQLKR--DQEEERRERWLKLEEEERREQQERREQQ 506 Query: 590 LQVELKSQEAQSLQQQQDHYRGHLQQYVAAYQQLASGKE 628 L+ E + + Q L++Q++ R LQQ + + QQL +E Sbjct: 507 LRREQEERREQRLKRQEEEER--LQQRLRSEQQLRREQE 543 Score = 143 bits (361), Expect = 4e-34 Identities = 105/355 (29%), Positives = 206/355 (58%), Gaps = 36/355 (10%) Query: 291 LNQQQEEKMWRQEEKIQEQEEKMCEQELKIRE---QEEKMWRQEEKMHEQEEKIREQEDK 347 L++++ + +E +Q++ ++ ++ + R+ +EE R+ +K EQE ++ E E++ Sbjct: 95 LDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQ 154 Query: 348 MWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEE---------EMWRQEEKIR 398 +QE EQ ++ R EE +WRQ ++ +E++E+ E+E+ E + EE++R Sbjct: 155 SEKQERL--EQRDRQRRDEE-LWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLR 211 Query: 399 EQ---EEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEE 455 + E +R+ + +Q+++ QD +E+EE+ WR+ E + EE +EE R+ E Sbjct: 212 RRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRE- 270 Query: 456 KMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLL--KQEEKIWEQEEKMWRQEEKMW 513 +QEEEE++++ E + R+E + +EQ+++ R+E+ L KQEE+ EQ+E+ Q+E+ Sbjct: 271 -LQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERRE 329 Query: 514 EQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGG 573 +QEE+ +E++++R++E+ REQ++R Q+EE+ ++Q R QE E R +L ++ +L Sbjct: 330 QQEER---REQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQL--- 383 Query: 574 AGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQQYVAAYQQLASGKE 628 RE +R L+ E + + Q L+++Q R +Q + QQL +E Sbjct: 384 -RREQQLRR----EQQLRREQQLRREQQLRREQQLRR---EQQLRREQQLRREQE 430 >gi|31317305 M-phase phosphoprotein 10 [Homo sapiens] Length = 681 Score = 176 bits (447), Expect = 5e-44 Identities = 144/469 (30%), Positives = 233/469 (49%), Gaps = 54/469 (11%) Query: 2 GGDNPEVSERANSSKFDPTKSPVLSDEDSDLDFHINKLEQQSKVRNKGHGKPREKSIADE 61 G + + + + K+ PV SDED + H ++L+ + + IA+E Sbjct: 251 GSKKLKSGKSSRNLKYKDFFDPVESDEDIT-NVHDDELDSNKE----------DDEIAEE 299 Query: 62 KFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGV 121 + +LS E DEDDDL+E+ED+KQ KESLKRVTF LPDD ED GV Sbjct: 300 EAEELSISET-------------DEDDDLQENEDNKQHKESLKRVTFALPDDAETEDTGV 346 Query: 122 SHVKKNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLH 181 +VKKNSDEVKSSF+KRQEKMNEK + K ++ KKPW GEVTAQKRPENSLLEETLH Sbjct: 347 LNVKKNSDEVKSSFEKRQEKMNEKIASLEKELLEKKPWQLQGEVTAQKRPENSLLEETLH 406 Query: 182 FDHAVRMGTYI--------EKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESE 233 FDHAVRM I E + K+R + + + + E+ KE E +++L L + E Sbjct: 407 FDHAVRMAPVITEETTLQLEDIIKQRIRD--QAWDDVVRKEKPKEDAYEYKKRLTL-DHE 463 Query: 234 KSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQ 293 KS++ L E+ + L QQ+ E + E+Q + L +++ ++ + Sbjct: 464 KSKL-----SLAEIYEQEYIKLNQQKTAEEENPEHVEIQKMMDSLFLKLDALSNFHFI-- 516 Query: 294 QQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEE 353 K E K+ I +E + E+I+E+ + Sbjct: 517 ----------PKPPVPEIKVVSNLPAITMEEVAPVSVSDAALLAPEEIKEKNKAGDIKTA 566 Query: 354 KIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEK 413 + +K RE+ +K +++ KI+E++++ + E+ Q K + EK+ + K Sbjct: 567 AEKTATDKKRERRKKKYQKRMKIKEKEKRRKLLEKSSVDQAGKY--SKTVASEKLKQLTK 624 Query: 414 KMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462 + K +++ + + +L++ ++ Q ++ E+K ++ ++ Sbjct: 625 TGKASFIKDEGKDKALKSSQAFFSKLQDQVKMQINDAKKTEKKKKKRQD 673 Score = 52.4 bits (124), Expect = 1e-06 Identities = 82/436 (18%), Positives = 193/436 (44%), Gaps = 71/436 (16%) Query: 199 RDAPSLELYRN----TITDEELKE-KNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQL 253 ++ P L+ ++N TI DE++ +E QE+ E + SEI+ + K+ LE ++ Sbjct: 83 QNEPILQYFQNAVSETINDEDISLLPESEEQER----EEDGSEIEADDKEDLEDLEEEEV 138 Query: 254 LLPQQQLQVEADRLGK--ELQSVSAKLQAQV---EENEL-WNLLNQQQEEKMW------- 300 + + +G+ E S S ++ V E+++L +++ +Q+ K+ Sbjct: 139 ----SDMGNDDPEMGERAENSSKSDLRKSPVFSDEDSDLDFDISKLEQQSKVQNKGQGKP 194 Query: 301 RQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQE-----EKIREQED--------- 346 R++ + ++ K+ E E + E++ R+++ E+E E I ED Sbjct: 195 REKSIVDDKFFKLSEMEAYLENIEKEEERKDDNDEEEEDIDFFEDIDSDEDEGGLFGSKK 254 Query: 347 -KMWRQEEKIREQE--EKIREQEEKMWRQEEKI---REQDEKIQEQEEEM----WRQEEK 396 K + ++ ++ + + E+ ++++ +E DE +E+ EE+ +++ Sbjct: 255 LKSGKSSRNLKYKDFFDPVESDEDITNVHDDELDSNKEDDEIAEEEAEELSISETDEDDD 314 Query: 397 IREQEEKRQEKMWRQEKKMREQDEKIREQEEEM---WRQEEKIRELEEMMQDQEEKLREV 453 ++E E+ +Q K + D+ E + +E E+ + EK+ + Sbjct: 315 LQENEDNKQHKESLKRVTFALPDDAETEDTGVLNVKKNSDEVKSSFEKRQEKMNEKIASL 374 Query: 454 EEKMQEEEE-KMQEQEEKIQRQEEKIQEQ---------------EEKTWRQEKLLKQE-- 495 E+++ E++ ++Q + +R E + E+ EE T + E ++KQ Sbjct: 375 EKELLEKKPWQLQGEVTAQKRPENSLLEETLHFDHAVRMAPVITEETTLQLEDIIKQRIR 434 Query: 496 EKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQ 555 ++ W+ + + +E +E ++++ EK + ++ EQE Q++ +E+ Sbjct: 435 DQAWDDVVRKEKPKEDAYEYKKRLTLDHEKSKLSLAEIYEQEYIKLNQQKTAEEENPEHV 494 Query: 556 ELEERLGKLGQKAELL 571 E+++ + L K + L Sbjct: 495 EIQKMMDSLFLKLDAL 510 Score = 47.4 bits (111), Expect = 4e-05 Identities = 55/257 (21%), Positives = 115/257 (44%), Gaps = 25/257 (9%) Query: 324 EEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIR---EQEEKIREQEEKMWRQEEKIREQD 380 +E++W+Q E +E + + +E I E EE+ RE++ ++K E Sbjct: 73 DEQIWQQLELQNEPILQYFQNAVSETINDEDISLLPESEEQEREEDGSEIEADDK--EDL 130 Query: 381 EKIQEQE-EEMWRQEEKIREQEEKRQEKMWRQEKKMREQDE-------KIREQEEEMWRQ 432 E ++E+E +M + ++ E+ E + R+ ++D K+ +Q + + Sbjct: 131 EDLEEEEVSDMGNDDPEMGERAENSSKSDLRKSPVFSDEDSDLDFDISKLEQQSKVQNKG 190 Query: 433 EEKIRELEEMMQDQEEKLREVE------EKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTW 486 + K RE + ++ D+ KL E+E EK +E ++ E+EE I E+ +++E Sbjct: 191 QGKPRE-KSIVDDKFFKLSEMEAYLENIEKEEERKDDNDEEEEDIDFFEDIDSDEDEGGL 249 Query: 487 RQEKLLKQEE-----KIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLW 541 K LK + K + + + E+ ++++ +E + EE+ E + Sbjct: 250 FGSKKLKSGKSSRNLKYKDFFDPVESDEDITNVHDDELDSNKEDDEIAEEEAEELSISET 309 Query: 542 QQEEKMQEQEVRLQELE 558 +++ +QE E Q E Sbjct: 310 DEDDDLQENEDNKQHKE 326 >gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo sapiens] Length = 693 Score = 155 bits (392), Expect = 1e-37 Identities = 109/424 (25%), Positives = 228/424 (53%), Gaps = 38/424 (8%) Query: 164 EVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEELK--EKNA 221 E Q+R + ++ E L H ++ ++++ ERD Y I E + E+ Sbjct: 194 EAVLQRRLQQTIKERALLNAHVTQVTESLKQVQLERDE-----YAKHIKGERARWQERMW 248 Query: 222 ELQEKLRLVESEKS-------EIQLNVKDLKRKLERAQLLLPQ------QQLQVEADRLG 268 ++ + R ++ EK E++ ++ +LK ++ L P +QLQ EA L Sbjct: 249 KMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLR 308 Query: 269 KELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMW 328 +E++ + KLQ+QVE N+ +LL+++Q++++ QEE ++EQE + ++ ++ EQ E++ Sbjct: 309 QEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLR 368 Query: 329 RQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEE 388 Q++ + EQ E++R+QE ++ +QEE++R++EE++++QE+++W QEE++ +++E++Q+QEE Sbjct: 369 EQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEE 428 Query: 389 EM-WRQEEKIREQEEKRQ---EKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQ 444 + Q K+ +Q + Q E + ++K + +++++E +E++ EE + + Q Sbjct: 429 RLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKL--DEEHLEAASQRNQ 486 Query: 445 DQEEKLREVEEKMQ-EEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEE 503 E +L V + + + + +EE+ R I E E + ++ + E Sbjct: 487 QLETQLSLVALPGEGDGGQHLDSEEEEAPRPTPNIPEDLESREATSSFMDLPKEKADGTE 546 Query: 504 KMWRQE----------EKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVR 553 ++ R+E + M E + Q + ++M E +RL Q+EE+M+ + + Sbjct: 547 QVERRELGFVQPSGVTDGMRESFTVYESQGAVPNTRHQEM-EDVIRLAQKEEEMKVKLLE 605 Query: 554 LQEL 557 LQEL Sbjct: 606 LQEL 609 Score = 146 bits (368), Expect = 7e-35 Identities = 124/521 (23%), Positives = 254/521 (48%), Gaps = 59/521 (11%) Query: 136 KKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKL 195 + RQ K+ ++ K P + G T +K+ ++S T H+ Y ++L Sbjct: 16 ESRQNKLAAAKKKLKEYQQRKSPGIPAGAKTKKKKTDSSPETTTSGGGHSPGDSQY-QEL 74 Query: 196 TKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEI-QLNVKDLKR----KLER 250 ++ S+ + + E LK++ +++ +L + +EI + ++ L+ LE+ Sbjct: 75 AVALESSSVTINQLNENIESLKQQKKQVEHQLEEAKKTNNEIHKAQMEQLETINILTLEK 134 Query: 251 AQLLLPQQQLQVEADRLGKELQSVSAKLQAQVE-----ENELWNLLNQQQEEKMWRQEEK 305 A L + A +E + ++ +LQ ++ E L + QQQEE R Sbjct: 135 ADLKTTLYHTKRAARHFEEESKDLAGRLQYSLQHIQELERALCAVSTQQQEED--RSSSC 192 Query: 306 IQEQEEKMCEQELKIRE-------------QEEKMWRQEEKMHEQEEKIREQEDKMWRQE 352 + ++ +Q +K R ++ ++ R E H + E+ R QE +MW+ Sbjct: 193 REAVLQRRLQQTIKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERARWQE-RMWKMS 251 Query: 353 EKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQE-----------EEMWRQEEKIREQE 401 + R +E+ + ++ E + E ++ E E++ + + +R++ Sbjct: 252 VEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQEV 311 Query: 402 EKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEE 461 E + K+ Q + + +EQ++ + QEE +RE E ++E+L E E+++E++ Sbjct: 312 EGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQ 371 Query: 462 EKMQEQEEKIQRQEEKIQEQEEKTWRQE-KLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQ 520 + +QEQ E++++QE+++++QEE+ ++E +L KQE+++W+QEE++W++EE++ +QEE++ Sbjct: 372 KTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLA 431 Query: 521 -EQEEKMQRQ-------------EEKMR---EQEVRLWQQ---EEKMQEQEVRLQELEER 560 Q K+ +Q E+K EQ+V+ Q+ EE ++ R Q+LE + Sbjct: 432 LSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASQRNQQLETQ 491 Query: 561 LGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQS 601 L + E GG +S + P TP + +L+S+EA S Sbjct: 492 LSLVALPGEGDGGQHLDSEEEEAPRPTPNIPEDLESREATS 532 >gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C isoform 1 [Homo sapiens] Length = 693 Score = 155 bits (392), Expect = 1e-37 Identities = 109/424 (25%), Positives = 228/424 (53%), Gaps = 38/424 (8%) Query: 164 EVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEELK--EKNA 221 E Q+R + ++ E L H ++ ++++ ERD Y I E + E+ Sbjct: 194 EAVLQRRLQQTIKERALLNAHVTQVTESLKQVQLERDE-----YAKHIKGERARWQERMW 248 Query: 222 ELQEKLRLVESEKS-------EIQLNVKDLKRKLERAQLLLPQ------QQLQVEADRLG 268 ++ + R ++ EK E++ ++ +LK ++ L P +QLQ EA L Sbjct: 249 KMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLR 308 Query: 269 KELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMW 328 +E++ + KLQ+QVE N+ +LL+++Q++++ QEE ++EQE + ++ ++ EQ E++ Sbjct: 309 QEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLR 368 Query: 329 RQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEE 388 Q++ + EQ E++R+QE ++ +QEE++R++EE++++QE+++W QEE++ +++E++Q+QEE Sbjct: 369 EQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEE 428 Query: 389 EM-WRQEEKIREQEEKRQ---EKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQ 444 + Q K+ +Q + Q E + ++K + +++++E +E++ EE + + Q Sbjct: 429 RLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKL--DEEHLEAASQRNQ 486 Query: 445 DQEEKLREVEEKMQ-EEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEE 503 E +L V + + + + +EE+ R I E E + ++ + E Sbjct: 487 QLETQLSLVALPGEGDGGQHLDSEEEEAPRPTPNIPEDLESREATSSFMDLPKEKADGTE 546 Query: 504 KMWRQE----------EKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVR 553 ++ R+E + M E + Q + ++M E +RL Q+EE+M+ + + Sbjct: 547 QVERRELGFVQPSGVTDGMRESFTVYESQGAVPNTRHQEM-EDVIRLAQKEEEMKVKLLE 605 Query: 554 LQEL 557 LQEL Sbjct: 606 LQEL 609 Score = 145 bits (367), Expect = 9e-35 Identities = 124/521 (23%), Positives = 254/521 (48%), Gaps = 59/521 (11%) Query: 136 KKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKL 195 + RQ K+ ++ K P + G T +K+ ++S T H+ Y ++L Sbjct: 16 ESRQNKLAAAKKKLKEYQQRKSPGIPAGAKTKKKKTDSSPETTTSGGGHSPGDSQY-QEL 74 Query: 196 TKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEI-QLNVKDLKR----KLER 250 ++ S+ + + E LK++ +++ +L + +EI + ++ L+ LE+ Sbjct: 75 AVALESSSVTINQLNENIESLKQQKKQVEHQLEEAKKTNNEIHKAQMEQLETINILTLEK 134 Query: 251 AQLLLPQQQLQVEADRLGKELQSVSAKLQAQVE-----ENELWNLLNQQQEEKMWRQEEK 305 A L + A +E + ++ +LQ ++ E L + QQQEE R Sbjct: 135 ADLKTTLYHTKRAARHFEEESKDLAGRLQYSLQRIQELERALSAVSTQQQEED--RSSSC 192 Query: 306 IQEQEEKMCEQELKIRE-------------QEEKMWRQEEKMHEQEEKIREQEDKMWRQE 352 + ++ +Q +K R ++ ++ R E H + E+ R QE +MW+ Sbjct: 193 REAVLQRRLQQTIKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERARWQE-RMWKMS 251 Query: 353 EKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQE-----------EEMWRQEEKIREQE 401 + R +E+ + ++ E + E ++ E E++ + + +R++ Sbjct: 252 VEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQEV 311 Query: 402 EKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEE 461 E + K+ Q + + +EQ++ + QEE +RE E ++E+L E E+++E++ Sbjct: 312 EGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQ 371 Query: 462 EKMQEQEEKIQRQEEKIQEQEEKTWRQE-KLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQ 520 + +QEQ E++++QE+++++QEE+ ++E +L KQE+++W+QEE++W++EE++ +QEE++ Sbjct: 372 KTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLA 431 Query: 521 -EQEEKMQRQ-------------EEKMR---EQEVRLWQQ---EEKMQEQEVRLQELEER 560 Q K+ +Q E+K EQ+V+ Q+ EE ++ R Q+LE + Sbjct: 432 LSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASQRNQQLETQ 491 Query: 561 LGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQS 601 L + E GG +S + P TP + +L+S+EA S Sbjct: 492 LSLVALPGEGDGGQHLDSEEEEAPRPTPNIPEDLESREATS 532 >gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo sapiens] Length = 693 Score = 154 bits (389), Expect = 2e-37 Identities = 108/424 (25%), Positives = 228/424 (53%), Gaps = 38/424 (8%) Query: 164 EVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEELK--EKNA 221 E +R + ++ E L H ++ ++++ ERD Y I E + E+ Sbjct: 194 EAVLHRRLQQTIKERALLNAHVTQVTESLKQVQLERDE-----YAKHIKGERARWQERMW 248 Query: 222 ELQEKLRLVESEKS-------EIQLNVKDLKRKLERAQLLLPQ------QQLQVEADRLG 268 ++ + R ++ EK E++ ++ +LK ++ + L P +QLQ EA L Sbjct: 249 KMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAKPPSLAPPAVTSVVEQLQDEAKHLR 308 Query: 269 KELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMW 328 +E++ + KLQ+QVE N+ +LL+++Q++++ QEE ++EQE + ++ ++ EQ E++ Sbjct: 309 QEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEVQRVREQERLCEQNERLR 368 Query: 329 RQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEE 388 Q++ + EQ E++R+QE ++ +QEE++R++EE++++QE+++W QEE++ +++E++Q+QEE Sbjct: 369 EQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEE 428 Query: 389 EM-WRQEEKIREQEEKRQ---EKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQ 444 + Q K+ +Q + Q E + ++K + +++++E +E++ EE + + Q Sbjct: 429 RLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKL--DEEHLEAASQQNQ 486 Query: 445 DQEEKLREVEEKMQ-EEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEE 503 E +L V + + + + +EE+ R I E E + ++ + E Sbjct: 487 QLETQLSLVALPGEGDGGQHLDSEEEEAPRPTPNIPEDLESREATSSFMDLPKEKADGTE 546 Query: 504 KMWRQE----------EKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVR 553 ++ R+E + M E + Q + ++M E +RL Q+EE+M+ + + Sbjct: 547 QVERRELGFVQPSGVTDGMRESFTVYESQGAVPNTRHQEM-EDVIRLAQKEEEMKVKLLE 605 Query: 554 LQEL 557 LQEL Sbjct: 606 LQEL 609 Score = 143 bits (361), Expect = 4e-34 Identities = 126/523 (24%), Positives = 260/523 (49%), Gaps = 63/523 (12%) Query: 136 KKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKL 195 + RQ K+ ++ K P + G T +K+ ++S T H+ Y ++L Sbjct: 16 ESRQNKLAAAKKKLKEYQQRKSPGIPAGAKTKKKKTDSSPETTTSGGGHSPGDSQY-QEL 74 Query: 196 TKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKR-------KL 248 ++ S+ + + E LK++ +++ +L E++K+ +++ ++R L Sbjct: 75 AVALESSSVTISQLNENIESLKQQKKQVEHQLE--EAKKTNNEIHKAQMERLETINILTL 132 Query: 249 ERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVE-----ENELWNLLNQQQEEKMWRQE 303 E+A L + A +E + ++ +LQ ++ E L + QQQEE R Sbjct: 133 EKADLKTTLYHTKRAARHFEEESKDLAGRLQYSLQRIQELERALCAVSTQQQEED--RSS 190 Query: 304 EKIQEQEEKMCEQELKIRE-------------QEEKMWRQEEKMHEQEEKIREQEDKMWR 350 + + +Q +K R ++ ++ R E H + E+ R QE +MW+ Sbjct: 191 SCREAVLHRRLQQTIKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERARWQE-RMWK 249 Query: 351 QEEKIRE-QEEKIRE--QEEKMWRQEEKIREQDEK--------IQEQEEEMWRQEEKIRE 399 + R +EEK R+ + +++ R +++ Q K + E++ + + +R+ Sbjct: 250 MSVEARTLKEEKKRDIHRIQELERSLSELKNQMAKPPSLAPPAVTSVVEQLQDEAKHLRQ 309 Query: 400 QEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQE 459 + E + K+ Q + + +EQ++ + QEE +RE E ++E+L E E+++E Sbjct: 310 EVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEVQRVREQERLCEQNERLRE 369 Query: 460 EEEKMQEQEEKIQRQEEKIQEQEEKTWRQE-KLLKQEEKIWEQEEKMWRQEEKMWEQEEK 518 +++ +QEQ E++++QE+++++QEE+ ++E +L KQE+++W+QEE++W++EE++ +QEE+ Sbjct: 370 QQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEER 429 Query: 519 MQ-EQEEKMQRQ-------------EEKMR---EQEVRLWQQ---EEKMQEQEVRLQELE 558 + Q K+ +Q E+K EQ+V+ Q+ EE ++ + Q+LE Sbjct: 430 LALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASQQNQQLE 489 Query: 559 ERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQS 601 +L + E GG +S + P TP + +L+S+EA S Sbjct: 490 TQLSLVALPGEGDGGQHLDSEEEEAPRPTPNIPEDLESREATS 532 >gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo sapiens] Length = 693 Score = 152 bits (383), Expect = 1e-36 Identities = 108/424 (25%), Positives = 226/424 (53%), Gaps = 38/424 (8%) Query: 164 EVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEELK--EKNA 221 E Q+ + ++ E L H ++ ++++ ERD Y I E + E+ Sbjct: 194 EAVLQRWLQQTIKERALLNAHVTQVTESLKQVQLERDE-----YAKHIKGERARWQERMW 248 Query: 222 ELQEKLRLVESEKS-------EIQLNVKDLKRKLERAQLLLPQ------QQLQVEADRLG 268 ++ + R ++ EK E++ ++ +LK ++ L P +QLQ EA L Sbjct: 249 KMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLR 308 Query: 269 KELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMW 328 +E++ + KLQ+QVE N+ +LL+++Q++++ QEE ++EQE + ++ ++ EQ E++ Sbjct: 309 QEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLR 368 Query: 329 RQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEE 388 Q++ + EQ E++R+QE ++ +QEE++R++EE++++QE+++W QEE++ +++E++Q+QEE Sbjct: 369 EQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEE 428 Query: 389 EM-WRQEEKIREQEEKRQ---EKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQ 444 + Q K+ +Q + Q E + ++K + +++++E +E++ EE + Q Sbjct: 429 RLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKL--DEEHLEAASHQNQ 486 Query: 445 DQEEKLREVEEKMQ-EEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEE 503 E +L V + + + + +EE+ R I E E + ++ + E Sbjct: 487 QLETQLSLVALPGEGDGGQHLDSEEEEAPRPTPNIPEDLESREATSSFMDLPKEKADGTE 546 Query: 504 KMWRQE----------EKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVR 553 ++ R+E + M E + Q + ++M E +RL Q+EE+M+ + + Sbjct: 547 QVERRELGFVQPSGVTDGMRESFTVYESQGAVPNTRHQEM-EDVIRLAQKEEEMKVKLLE 605 Query: 554 LQEL 557 LQEL Sbjct: 606 LQEL 609 Score = 144 bits (364), Expect = 2e-34 Identities = 123/523 (23%), Positives = 256/523 (48%), Gaps = 63/523 (12%) Query: 136 KKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKL 195 + RQ K+ ++ K P + G T +K+ ++S T H+ Y ++L Sbjct: 16 ESRQNKLAAAKKKLKEYQQRKSPGIPAGAKTKKKKTDSSPETTTSGGCHSPGDSQY-QEL 74 Query: 196 TKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKR-------KL 248 ++ S+ + + E LK++ +++ +L E++K+ +++ ++R L Sbjct: 75 AVALESSSVTISQLNENIESLKQQKKQVEHQLE--EAKKTNNEIHKAQMERLETINILTL 132 Query: 249 ERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVE-----ENELWNLLNQQQEEKMWRQE 303 E+A L + A +E + ++ +LQ ++ E L + QQQEE R Sbjct: 133 EKADLKTTLYHTKRAARHFEEESKDLAGRLQYSLQRIQELERALCAVSTQQQEED--RSS 190 Query: 304 EKIQEQEEKMCEQELKIRE-------------QEEKMWRQEEKMHEQEEKIREQEDKMWR 350 + ++ +Q +K R ++ ++ R E H + E+ R QE +MW+ Sbjct: 191 SCREAVLQRWLQQTIKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERARWQE-RMWK 249 Query: 351 QEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQE-----------EEMWRQEEKIRE 399 + R +E+ + ++ E + E ++ E E++ + + +R+ Sbjct: 250 MSVEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQ 309 Query: 400 QEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQE 459 + E + K+ Q + + +EQ++ + QEE +RE E ++E+L E E+++E Sbjct: 310 EVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLRE 369 Query: 460 EEEKMQEQEEKIQRQEEKIQEQEEKTWRQE-KLLKQEEKIWEQEEKMWRQEEKMWEQEEK 518 +++ +QEQ E++++QE+++++QEE+ ++E +L KQE+++W+QEE++W++EE++ +QEE+ Sbjct: 370 QQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEER 429 Query: 519 MQ-EQEEKMQRQ-------------EEKMR---EQEVRLWQQ---EEKMQEQEVRLQELE 558 + Q K+ +Q E+K EQ+V+ Q+ EE ++ + Q+LE Sbjct: 430 LALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASHQNQQLE 489 Query: 559 ERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQS 601 +L + E GG +S + P TP + +L+S+EA S Sbjct: 490 TQLSLVALPGEGDGGQHLDSEEEEAPRPTPNIPEDLESREATS 532 >gi|221219020 NYD-SP11 protein [Homo sapiens] Length = 2873 Score = 148 bits (374), Expect = 1e-35 Identities = 89/383 (23%), Positives = 214/383 (55%), Gaps = 35/383 (9%) Query: 214 EELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQS 273 E+L + LQE +L E ++ N+ K K E+ + L+ E R G+E + Sbjct: 1501 EKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSK-EQQYKDEEEVTLEEEVSREGEEKEQ 1559 Query: 274 VSAKLQAQVEENELWNLLNQQQ---EEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQ 330 + Q ++E W +++++ E+K ++E K+ ++EEK+ ++E ++ ++E K+ + Sbjct: 1560 QVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQA 1619 Query: 331 EEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEM 390 K+ + + ++ + E K ++EE + ++ EK+ ++ EK+ ++ +K+ ++ EK+ +EE++ Sbjct: 1620 YVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKL 1679 Query: 391 WRQ-----------EEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEE----- 434 ++ +K+ E ++ Q W++++ +E +E + EE W++EE Sbjct: 1680 AKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEE 1739 Query: 435 --------KIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTW 486 K+ E EE + Q EKL E E K+ +EEE + +++EK+ + +EK+ E+EE+ Sbjct: 1740 GKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLG 1799 Query: 487 R-QEKLLKQEEKIWEQEEKMWRQEEKMWE------QEEKMQEQEEKMQRQEEKMREQEVR 539 R +E+L++++ K+ ++ E+ E++ + Q++ + ++++ + +++EK+ +++ Sbjct: 1800 RKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKEN 1859 Query: 540 LWQQEEKMQEQEVRLQELEERLG 562 L +E++ + +L +++ +LG Sbjct: 1860 LLYNKERLTHSKKQLVQVKNKLG 1882 Score = 143 bits (361), Expect = 4e-34 Identities = 127/473 (26%), Positives = 242/473 (51%), Gaps = 47/473 (9%) Query: 121 VSHVKKNSDEVKSSFKKRQEKMNEKNY--TFRKRVVIKKPWLRLGEVTAQKRPENSLLEE 178 ++ +K +V+ S K+QEK+ ++ K +V K LR GE+ K + LE Sbjct: 1909 LAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLR-GELDIAKEEKALNLEM 1967 Query: 179 TLHFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKL-----RLVESE 233 + +R+ E L+K + + T ++EL E+ L+EK+ R++ E Sbjct: 1968 KRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKILLHEDRILAME 2027 Query: 234 KSEIQLNVKDLKRKLE--RAQLLLPQQQ--LQVEADRLGKELQSVSAKLQAQVEENELWN 289 +SEI K KLE R Q + Q Q L + +L K+ +S+S E +L Sbjct: 2028 ESEIA------KGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSK------EPAKLNK 2075 Query: 290 LLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMW 349 +L Q K+ R E K+ ++E KM + + + +E ++ ++ K+ +E E+ ++ Sbjct: 2076 ILKALQ--KLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELT 2133 Query: 350 RQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQ---- 405 + E+K+ ++ K+ + +M +EEK+ E++ K+ + E+ +E+ EE+ Sbjct: 2134 KDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFL 2193 Query: 406 EKMWRQEKKMREQD---EKIREQEEEMWRQEEKIRELEEMMQDQE-------EKLREVEE 455 ++ WR+ K+ + D EK Q +E+ +E E+E ++ + E E+ E EE Sbjct: 2194 KRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREE 2253 Query: 456 KMQEEEEKMQEQEEKIQRQ---EEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKM 512 + + EEE+++E+EE+ + + EEK E+EE+ +++K K++E++ E+EE +EE M Sbjct: 2254 EEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIM 2313 Query: 513 WEQEEKM----QEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERL 561 E+E + +E+EE +EE RE+E+ +++ K+QEQ + ER+ Sbjct: 2314 SEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRRKSLRGRERV 2366 Score = 138 bits (347), Expect = 2e-32 Identities = 120/580 (20%), Positives = 285/580 (49%), Gaps = 40/580 (6%) Query: 25 LSDEDSDLDFHINKLE--QQSKVRNKGHGKPREKSIADEKFFQLSEMEAYLENRKRRGTK 82 ++ E+ D+ + ++ ++ V+ +G E++ + + + + + + R+ K Sbjct: 1420 MTKEERDMSEEVEEMATLEEKVVKQEGKLVMIERTPSWQDWKKAWDEWKQVHGETRKSWK 1479 Query: 83 RWDEDDD---LEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSFKKRQ 139 W E+ + L+E E Q E L L +D+ ++ V +N + SS K Q Sbjct: 1480 AWKEEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWEN---MLSSKSKEQ 1536 Query: 140 EKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKER 199 + +E+ T + V R GE E + EE H + K + Sbjct: 1537 QYKDEEEVTLEEEVS------REGE-----EKEQQVTEEQRHIQEEHKWARIHRKRARAE 1585 Query: 200 DAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQ 259 + E + +E+L QE+ +L + E+ Q VK + E AQ Q Sbjct: 1586 KKRAQEERKLAQEEEKLA------QEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQ 1639 Query: 260 LQVEADRLGKELQSVSAKL-QAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQEL 318 + + G++L + KL Q + + + W EK+ R+EEK+ ++ K+ E + Sbjct: 1640 KEETLAQRGEKLSQEAEKLAQKRKKLAKKW--------EKVAREEEKLAKKGGKLAEVKN 1691 Query: 319 KIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIRE 378 + ++ E++ ++E+ + QE+++ ++ +++ E++ +EE++ ++E K+ +++K+ E Sbjct: 1692 ILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAE 1751 Query: 379 QDEKIQEQEEEMWRQEEKIREQEE---KRQEKMWRQEKKMREQDEKIREQEEEMWRQEEK 435 ++E + Q E++ +E K+ ++EE + +EK+ + ++KM E++E++ + E++ ++ K Sbjct: 1752 EEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMK 1811 Query: 436 IRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQE 495 + + E + E+L + + + +++ QE++ Q +E+ Q +E + +E+L + Sbjct: 1812 LAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSK 1871 Query: 496 EKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQ 555 +++ + + K+ + + + EEK+ +++E + +++EK+ E E +L Q E+ + +++ + Sbjct: 1872 KQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQ---E 1928 Query: 556 ELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELK 595 +L + KL + ++ G R G + L +E+K Sbjct: 1929 KLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKALNLEMK 1968 Score = 132 bits (333), Expect = 8e-31 Identities = 123/568 (21%), Positives = 265/568 (46%), Gaps = 70/568 (12%) Query: 131 VKSSFKKRQEKMNEKNYTFRKRVVIKK--PWLRLGEVTAQKRPENSLLEETLHFDHAVRM 188 + S K E +N + TF + +++ + W E+ + E+ +L E L +D Sbjct: 1254 ISGSQTKMSENLNAELVTFAQEMLVDRHPSWELFQEICPLLKKESKVLLEDLDWD----- 1308 Query: 189 GTYIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKL 248 + + + I ++ ++ E+ ++ E+ + Q +D+ L Sbjct: 1309 -------VVPPEKKPIFIQEGAIREDMIQGVTQEVIRHKEVMPREEEQAQKKARDMLG-L 1360 Query: 249 ERAQLLLPQQQLQVEAD----RLGKELQSVSAKLQAQVEENELWNLLNQQQE-----EKM 299 E Q++L + + + + +GKE+ K Q + + ++++ +M Sbjct: 1361 EETQVILKKGKKVIFLEPGNVTMGKEISKKEEKKTFQKSPKQGRKAVQKERKVGKIKREM 1420 Query: 300 WRQEEKIQEQEEKMCEQELKIREQEEKM--------WRQEEKMHEQEEKIREQEDKMWRQ 351 ++E + E+ E+M E K+ +QE K+ W+ +K ++ +++ + K W+ Sbjct: 1421 TKEERDMSEEVEEMATLEEKVVKQEGKLVMIERTPSWQDWKKAWDEWKQVHGETRKSWKA 1480 Query: 352 -----EEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQ--EEKIREQEEKR 404 E+++ ++EEK+ + EK+ +EE ++E + E+ +++W K +EQ+ K Sbjct: 1481 WKEEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKD 1540 Query: 405 QEKMWRQEKKMREQDEKIRE--------QEEEMW--------RQEEKIRELEEMMQDQEE 448 +E++ +E+ RE +EK ++ QEE W R E+K + E + +EE Sbjct: 1541 EEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEE 1600 Query: 449 KLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQE-EKIWEQEEKMWR 507 KL + E ++ +EE K+ + KI + + ++ + E K ++E+ L Q EK+ ++ EK+ + Sbjct: 1601 KLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQ 1660 Query: 508 QEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKM---------QEQEV--RLQE 556 + +K+ ++ EK+ +EEK+ ++ K+ E + L Q+ E++ QE+E+ L+E Sbjct: 1661 KRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEE 1720 Query: 557 LEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQQY 616 LE + +L K E L +E G + E + + + L +++ + Sbjct: 1721 LEWDMEELSWKEEEL---NQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELL 1777 Query: 617 VAAYQQLASGKEALPSCSSRKLRAKRWL 644 + ++LA KE +P R R + L Sbjct: 1778 IQEKEKLAQHKEKMPEEEERLGRKREQL 1805 Score = 115 bits (288), Expect = 1e-25 Identities = 125/566 (22%), Positives = 272/566 (48%), Gaps = 63/566 (11%) Query: 51 GKPREKSIADE--------KFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKES 102 G+ +E+ + +E K+ ++ A E ++ + ++ ++++ E+ + +E Sbjct: 1554 GEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEE 1613 Query: 103 LKR----VTFTLPDDEAIEDAG---------VSHVKKNSDEVKSSFKKRQEKMNEKNYTF 149 K V T D E + G +K S E + +KR++ + Sbjct: 1614 RKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVA 1673 Query: 150 RKRVVIKKPWLRLGEVT---AQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDAPSLEL 206 R+ + K +L EV AQK E E+ L + ++L +E + ++ Sbjct: 1674 REEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQE--------KELAQELEELEWDM 1725 Query: 207 YRNTITDEELKEKNAEL-QEKLRLVESEKS-----------EIQLNVKDLKRKLERAQLL 254 + +EEL ++ +L +EK +L E E++ E +L ++ E+ +L Sbjct: 1726 EELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLA 1785 Query: 255 LPQQQLQVEADRLGKELQSVSAKLQAQVEENELW-NLLNQQQEEKMWRQEEKIQEQEEKM 313 ++++ E +RLG++ + + K ++ E W N + + + KM ++K QE+K Sbjct: 1786 QHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKN 1845 Query: 314 CEQEL-KIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQ 372 QE K+ +++E + +E++ ++++ + ++K+ + + + EEK+ +++E + ++ Sbjct: 1846 LAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKK 1905 Query: 373 EEKIREQDEKIQEQEEEMWRQEEKIREQEEK-RQEKMWRQEKKMREQDEKIREQEE---- 427 +EK+ E ++K+ + E+ + +++EK+ +++ K EK Q KK + I ++E+ Sbjct: 1906 KEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKALNL 1965 Query: 428 EMWR-QEEKIRELE--EMMQDQEEKLREVEEKMQEEEEKMQEQ----EEKIQRQEEKIQE 480 EM R EEK+R +E E + E + KM + E+++ E+ EEKI E++I Sbjct: 1966 EMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKILLHEDRILA 2025 Query: 481 QEEKTWRQEKL-LKQEEKIWEQ-EEKMWRQEEKMWEQEEKMQEQEEKMQ---RQEEKMRE 535 EE + KL + ++I+ Q + K+ + K+ ++ E + ++ K+ + +K+ Sbjct: 2026 MEESEIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLNKILKALQKLTR 2085 Query: 536 QEVRLWQQEEKMQEQEVRLQELEERL 561 E +L Q+E KM + + L E RL Sbjct: 2086 DERKLTQEEIKMTKMKRALFVKERRL 2111 Score = 107 bits (268), Expect = 3e-23 Identities = 133/602 (22%), Positives = 290/602 (48%), Gaps = 101/602 (16%) Query: 54 REKSIADEKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDD 113 +++ +A EK M+ LE +G KR + D+ + E K +KR+ Sbjct: 1926 KQEKLAQEK------MKLALEKAMVQGKKRLRGELDIAKEE--KALNLEMKRL------- 1970 Query: 114 EAIEDAGVSHVKKNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPEN 173 A E + K+ + ++ RQ KM + +R + + + L E E+ Sbjct: 1971 -AEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKILLHEDRILAMEES 2029 Query: 174 SLLEETLHFDHAVR--------MGTYIEKLTKERDAPSLELYRNTITDEELKEKNAELQE 225 + + L F R + KL K+R++ S E + ++ LK ++ Sbjct: 2030 EIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAK---LNKILKALQKLTRD 2086 Query: 226 KLRLVESE----KSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQ 281 + +L + E K + L VK+ + +E+++L + + + L K+ + ++ K + Sbjct: 2087 ERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQRKL 2146 Query: 282 VEENELWNLLNQQQEEKMWRQEEKIQEQEEKMC---EQELKIREQE-----EKMWRQEEK 333 N++ ++N+ EEKM +E K+ + ++ E+E I E+E ++ WR+ ++ Sbjct: 2147 A--NKMRRMINK--EEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKE 2202 Query: 334 MH---EQEEKIREQEDKMWRQEEKIREQE---EKIREQEEKMWRQEEKIREQDEKIQEQE 387 + +EK Q D++ +E E E +++ +QE +EE+ E++E Sbjct: 2203 AKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEE------ 2256 Query: 388 EEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQE 447 R+EE++RE+EE+R+E+ +EK++ +++E+ +++++E +++E+++E EE+ +++E Sbjct: 2257 ----REEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKE--KKKEEVQEKEEVFEEKE 2310 Query: 448 EKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEE--KIWEQEEKM 505 E + E EE E + ++EE EE+ EE+ R++++LK+E+ K+ EQ K Sbjct: 2311 EIMSE------EETESLSDEEE-----EEESCSLEEEVDREKEILKKEKQFKLQEQRRKS 2359 Query: 506 WRQEEKMWE-------------QEEKMQEQEEKMQRQEEKMREQ-EVRLWQQEEKMQEQE 551 R E++ + ++ +K+ +M+E+ V + +++ ++++ Sbjct: 2360 LRGRERVLSILRGVPHGKGRAIRLGVLKSPLKKLMSTALEMKEKTPVPVPEKQISWEDKK 2419 Query: 552 VRLQELEER-LGKLGQKAELLG----------GAGRESGSQRL--PTLTPILQVELKSQE 598 + E+ + LG + ++ E++G G ES +Q L P ++ IL+ ++++E Sbjct: 2420 ATVVEIPRKFLGTMDKEREVMGKYEPIPPHVLGTVLESQAQDLKTPFMSHILRRTVEAEE 2479 Query: 599 AQ 600 Q Sbjct: 2480 LQ 2481 >gi|194097392 Golgi autoantigen, golgin subfamily a, 2 [Homo sapiens] Length = 1002 Score = 143 bits (361), Expect = 4e-34 Identities = 125/491 (25%), Positives = 240/491 (48%), Gaps = 63/491 (12%) Query: 191 YIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLER 250 Y ++LTKERDA LELY+NT ++E+LK++ +EL+EKLR++ +EK+ +QLN+++L++KLE Sbjct: 285 YNKELTKERDALRLELYKNTQSNEDLKQEKSELEEKLRVLVTEKAGMQLNLEELQKKLEM 344 Query: 251 AQLLLPQQQLQVEADRLGKEL-QSVSAKLQAQVEENELWNLLNQQQEEK----------- 298 +LLL Q + EA ++L Q++ + Q + ++ + Q Q E+ Sbjct: 345 TELLLQQFSSRCEAPDANQQLQQAMEERAQLEAHLGQVMESVRQLQMERDKYAENLKGES 404 Query: 299 -MWRQE-EKIQEQ-----EEKMCE----QELKIREQEEKMWRQEEKMHEQEEKIREQEDK 347 MWRQ +++ EQ EEK C QEL+ E + E E E E + Sbjct: 405 AMWRQRMQQMSEQVHTLREEKECSMSRVQELETSLAELRNQMAEPPPPEPPAGPSEVEQQ 464 Query: 348 MWRQEEKIREQEEKIREQEEKMWRQEEKI----REQDEKIQEQEE--EMWRQEEKIREQ- 400 + + E +R++ E + Q + + E + REQ+E++ E E E+W ++ + R Q Sbjct: 465 LQAEAEHLRKELEGLAGQLQAQVQDNEGLSRLNREQEERLLELERAAELWGEQAEARRQI 524 Query: 401 ---EEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKM 457 + + + R + RE E++ E + + + E+ +Q ++ RE+ +K+ Sbjct: 525 LETMQNDRTTISRALSQNRELKEQLAELQSGFVKLTNENMEITSALQSEQHVKRELGKKL 584 Query: 458 QEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEE 517 E +EK+ E +E ++ + ++ Q +++ + L+Q ++Q E+++ + Sbjct: 585 GELQEKLSELKETVELKSQEAQSLQQQRDQYLGHLQQYVAAYQQ----LTSEKEVLHNQL 640 Query: 518 KMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRE 577 +Q Q +Q+E + + +QE +QE + RL+ ++ +L + L+ G Sbjct: 641 LLQTQLVDQLQQQEAQGKAVAEMARQE--LQETQERLEAATQQNQQLRAQLSLMAHPGEG 698 Query: 578 SGSQR---------------LPTLTPILQVELKSQEAQ---------SLQQQQDHYRGHL 613 G R +P P + +L+S+EA S +++Q RG L Sbjct: 699 DGLDREEEEDEEEEEEEAVAVPQPMPSIPEDLESREAMVAFFNSAVASAEEEQARLRGQL 758 Query: 614 QQYVAAYQQLA 624 ++ ++LA Sbjct: 759 KEQRVRCRRLA 769 Score = 118 bits (296), Expect = 2e-26 Identities = 132/480 (27%), Positives = 225/480 (46%), Gaps = 85/480 (17%) Query: 211 ITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKL------------ERAQLLLPQQ 258 IT E+LK++N E+ ++L E EK E L+ +L E+A+L Sbjct: 182 ITIEKLKQQNQEITDQL---EEEKKECHQKQGALREQLQVHIQTIGILVSEKAELQTALA 238 Query: 259 QLQVEADRLGKELQSVSAKLQ-AQVEENELWNLLN--QQQEEKMWRQEEKIQEQEEKMCE 315 Q A + E + ++++LQ ++ EL L+ Q++K R +++ ++ + + Sbjct: 239 HTQHAARQKEGESEDLASRLQYSRRRVGELERALSAVSTQQKKADRYNKELTKERDAL-R 297 Query: 316 QELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEK 375 EL Q + +QE+ E EEK+R + + + E ++K+ E + + + Sbjct: 298 LELYKNTQSNEDLKQEKS--ELEEKLRVLVTEKAGMQLNLEELQKKLEMTELLLQQFSSR 355 Query: 376 IREQD--EKIQEQEEEMWRQE-------EKIREQEEKR---------QEKMWRQE-KKMR 416 D +++Q+ EE + E E +R+ + +R + MWRQ ++M Sbjct: 356 CEAPDANQQLQQAMEERAQLEAHLGQVMESVRQLQMERDKYAENLKGESAMWRQRMQQMS 415 Query: 417 EQDEKIREQEE-EMWRQEEKIRELEEMMQDQEEKL--------REVEEKMQEEEEKMQEQ 467 EQ +RE++E M R +E L E+ E EVE+++Q E E ++++ Sbjct: 416 EQVHTLREEKECSMSRVQELETSLAELRNQMAEPPPPEPPAGPSEVEQQLQAEAEHLRKE 475 Query: 468 EEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEE--KMWRQEEKMWEQE-EKMQEQEE 524 E + Q + + E R + +QEE++ E E ++W ++ + Q E MQ Sbjct: 476 LEGLAGQLQAQVQDNEGLSRLNR--EQEERLLELERAAELWGEQAEARRQILETMQNDRT 533 Query: 525 KMQR---QEEKMREQEVRLWQQEEKMQEQEVRL-----------QELEERLGKLGQKAEL 570 + R Q +++EQ L K+ + + + +EL ++LG+L +K Sbjct: 534 TISRALSQNRELKEQLAELQSGFVKLTNENMEITSALQSEQHVKRELGKKLGELQEKLSE 593 Query: 571 LGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQQYVAAYQQLASGKEAL 630 L +E+ VELKSQEAQSLQQQ+D Y GHLQQYVAAYQQL S KE L Sbjct: 594 L----KET-------------VELKSQEAQSLQQQRDQYLGHLQQYVAAYQQLTSEKEVL 636 Score = 88.2 bits (217), Expect = 2e-17 Identities = 110/558 (19%), Positives = 245/558 (43%), Gaps = 51/558 (9%) Query: 74 ENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKS 133 E K R R + + + +ED KQ K L+ L ++A ++ N +E++ Sbjct: 288 ELTKERDALRLELYKNTQSNEDLKQEKSELEEKLRVLVTEKA-------GMQLNLEELQK 340 Query: 134 SFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIE 193 + + +++++ R A ++ + ++ E H ++ + Sbjct: 341 KLEMTE-------------LLLQQFSSRCEAPDANQQLQQAMEERAQLEAHLGQVMESVR 387 Query: 194 KLTKERDAPSLELYRNTITDEEL--KEKNAELQEKLRLVESEKSEIQLNVKDLKRKLE-- 249 +L ERD Y + E +++ ++ E++ + EK V++L+ L Sbjct: 388 QLQMERDK-----YAENLKGESAMWRQRMQQMSEQVHTLREEKECSMSRVQELETSLAEL 442 Query: 250 RAQLLLP------------QQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEE 297 R Q+ P +QQLQ EA+ L KEL+ ++ +LQAQV++NE + LN++QEE Sbjct: 443 RNQMAEPPPPEPPAGPSEVEQQLQAEAEHLRKELEGLAGQLQAQVQDNEGLSRLNREQEE 502 Query: 298 KMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIRE 357 ++ + E+ E + E +I E + + Q +++EQ ++ K+ Sbjct: 503 RLL-ELERAAELWGEQAEARRQILETMQNDRTTISRALSQNRELKEQLAELQSGFVKLTN 561 Query: 358 QEEKIRE--QEEKMWRQE--EKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEK 413 + +I Q E+ ++E +K+ E EK+ E +E + + ++ + +++R + + ++ Sbjct: 562 ENMEITSALQSEQHVKRELGKKLGELQEKLSELKETVELKSQEAQSLQQQRDQYLGHLQQ 621 Query: 414 KMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQR 473 + +++ ++E + Q +L + +Q QE + + V E ++E ++ QE+ E + Sbjct: 622 YVAAY-QQLTSEKEVLHNQLLLQTQLVDQLQQQEAQGKAVAEMARQELQETQERLEAATQ 680 Query: 474 QEEKIQEQEEKTWRQEKL----LKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQ 529 Q ++++ Q + ++EE E+EE+ + M E ++ +E + Sbjct: 681 QNQQLRAQLSLMAHPGEGDGLDREEEEDEEEEEEEAVAVPQPMPSIPEDLESREAMVAFF 740 Query: 530 EEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPI 589 + E + +++EQ VR + L L ++ E A G Sbjct: 741 NSAVASAEEEQARLRGQLKEQRVRCRRLAHLLASAQKEPEAAAPAPGTGGDSVCGETHRA 800 Query: 590 LQVELKSQEAQSLQQQQD 607 LQ ++ +++ ++ Q+ Sbjct: 801 LQGAMEKLQSRFMELMQE 818 Score = 45.4 bits (106), Expect = 2e-04 Identities = 58/304 (19%), Positives = 128/304 (42%), Gaps = 40/304 (13%) Query: 215 ELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKEL--- 271 EL+EK +EL+E + L E +Q L+ Q + QQL E + L +L Sbjct: 586 ELQEKLSELKETVELKSQEAQSLQQQRDQYLGHLQ--QYVAAYQQLTSEKEVLHNQLLLQ 643 Query: 272 -QSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQE-EKMWR 329 Q V Q + + + + Q+ +E R E Q+ ++ + L E + + R Sbjct: 644 TQLVDQLQQQEAQGKAVAEMARQELQETQERLEAATQQNQQLRAQLSLMAHPGEGDGLDR 703 Query: 330 QEEKMHEQEEK--------IREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDE 381 +EE+ E+EE+ + + + +E + + EE+ R +++EQ Sbjct: 704 EEEEDEEEEEEEAVAVPQPMPSIPEDLESREAMVAFFNSAVASAEEEQARLRGQLKEQRV 763 Query: 382 KIQE--------QEE-----------------EMWRQEEKIREQEEKRQEKMWRQEKKMR 416 + + Q+E E R + E+ + R ++ +++ ++ Sbjct: 764 RCRRLAHLLASAQKEPEAAAPAPGTGGDSVCGETHRALQGAMEKLQSRFMELMQEKADLK 823 Query: 417 EQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEE 476 E+ E++ + ++ + + I E + Q Q L+E + +E ++ + +E+++ + Sbjct: 824 ERVEELEHRCIQLSGETDTIGEYIALYQSQRAVLKERHREKEEYISRLAQDKEEMKVKLL 883 Query: 477 KIQE 480 ++QE Sbjct: 884 ELQE 887 Score = 40.8 bits (94), Expect = 0.004 Identities = 70/418 (16%), Positives = 174/418 (41%), Gaps = 52/418 (12%) Query: 68 EMEAYLENRKRRGTKRWDEDDDLEESEDSKQC----KESLKRVTFTLPDDEAIEDAGVSH 123 +++A +++ + ++++ L E E + + E+ +++ T+ +D +S Sbjct: 482 QLQAQVQDNEGLSRLNREQEERLLELERAAELWGEQAEARRQILETMQNDRTTISRALSQ 541 Query: 124 ---VKKNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETL 180 +K+ E++S F K + E + +K+ LG+ + + + S L+ET+ Sbjct: 542 NRELKEQLAELQSGFVKLTNENMEITSALQSEQHVKR---ELGKKLGELQEKLSELKETV 598 Query: 181 HFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLN 240 + L ++RD L + ++L + L +L L ++Q Sbjct: 599 ELK-----SQEAQSLQQQRDQYLGHLQQYVAAYQQLTSEKEVLHNQLLLQTQLVDQLQQQ 653 Query: 241 VKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMW 300 K E A+ L + Q ++EA ++ Q + A+L E L +++E++ Sbjct: 654 EAQGKAVAEMARQELQETQERLEAAT--QQNQQLRAQLSLMAHPGEGDGLDREEEEDEEE 711 Query: 301 RQEEKIQ-EQEEKMCEQELKIREQ------------EEKMWRQEEKMHEQEEKIREQEDK 347 +EE + Q ++L+ RE EE+ R ++ EQ + R Sbjct: 712 EEEEAVAVPQPMPSIPEDLESREAMVAFFNSAVASAEEEQARLRGQLKEQRVRCRRLAHL 771 Query: 348 MWRQEEK----------------------IREQEEKIREQEEKMWRQEEKIREQDEKIQE 385 + +++ ++ EK++ + ++ +++ ++E+ E+++ Sbjct: 772 LASAQKEPEAAAPAPGTGGDSVCGETHRALQGAMEKLQSRFMELMQEKADLKERVEELEH 831 Query: 386 QEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMM 443 + ++ + + I E Q + +++ RE++E I ++ + K+ EL+E++ Sbjct: 832 RCIQLSGETDTIGEYIALYQSQRAVLKERHREKEEYISRLAQDKEEMKVKLLELQELV 889 >gi|169210281 PREDICTED: similar to M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) [Homo sapiens] Length = 213 Score = 140 bits (352), Expect = 5e-33 Identities = 79/143 (55%), Positives = 99/143 (69%), Gaps = 9/143 (6%) Query: 1 MGGDNPEVSERA-NSSKFDPTKSPVLSDEDSDLDFHINKLEQQSKVRNKGHGKPREKSIA 59 MGGDNPEV ++A NSSKF+ KSPV SDEDSDLDF I+KLEQQSKV+N GHGKPREKSI Sbjct: 63 MGGDNPEVGKKARNSSKFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSII 122 Query: 60 DEKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDA 119 DEKFFQLSEMEAYLENR++ ++ D DD+ +S + K+ V E+ ED Sbjct: 123 DEKFFQLSEMEAYLENREKEEERKDDNDDESGKSSRNVNNKDFFDPV-------ESDEDI 175 Query: 120 GVSHVKK-NSDEVKSSFKKRQEK 141 H + S+++ KK+Q+K Sbjct: 176 ASDHDDELGSNKMMKLLKKKQKK 198 Score = 35.8 bits (81), Expect = 0.13 Identities = 34/137 (24%), Positives = 61/137 (44%), Gaps = 6/137 (4%) Query: 430 WRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQE 489 W+ E E EE Q+ EE E E QE+ E +QE+EE + E +K Sbjct: 22 WQIVELGEESEE--QECEEDGSETETGGQEDLEDLQEEEEVSDMGGDN-PEVGKKARNSS 78 Query: 490 KLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQE---EK 546 K ++ ++ E+ + EQ+ K+Q R++ + E+ +L + E E Sbjct: 79 KFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLEN 138 Query: 547 MQEQEVRLQELEERLGK 563 +++E R + ++ GK Sbjct: 139 REKEEERKDDNDDESGK 155 >gi|169210488 PREDICTED: similar to M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) [Homo sapiens] Length = 213 Score = 140 bits (352), Expect = 5e-33 Identities = 79/143 (55%), Positives = 99/143 (69%), Gaps = 9/143 (6%) Query: 1 MGGDNPEVSERA-NSSKFDPTKSPVLSDEDSDLDFHINKLEQQSKVRNKGHGKPREKSIA 59 MGGDNPEV ++A NSSKF+ KSPV SDEDSDLDF I+KLEQQSKV+N GHGKPREKSI Sbjct: 63 MGGDNPEVGKKARNSSKFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSII 122 Query: 60 DEKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDA 119 DEKFFQLSEMEAYLENR++ ++ D DD+ +S + K+ V E+ ED Sbjct: 123 DEKFFQLSEMEAYLENREKEEERKDDNDDESVKSSRNVNNKDFFDPV-------ESDEDI 175 Query: 120 GVSHVKK-NSDEVKSSFKKRQEK 141 H + S+++ KK+Q+K Sbjct: 176 ASDHDDELGSNKMMKLLKKKQKK 198 Score = 33.5 bits (75), Expect = 0.64 Identities = 30/122 (24%), Positives = 54/122 (44%), Gaps = 3/122 (2%) Query: 430 WRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQE 489 W+ E E EE Q+ EE E E QE+ E +QE+EE + E +K Sbjct: 22 WQIVELGEESEE--QECEEDGSETETGGQEDLEDLQEEEEVSDMGGDN-PEVGKKARNSS 78 Query: 490 KLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQE 549 K ++ ++ E+ + EQ+ K+Q R++ + E+ +L + E ++ Sbjct: 79 KFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLEN 138 Query: 550 QE 551 +E Sbjct: 139 RE 140 >gi|169210051 PREDICTED: similar to M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) [Homo sapiens] Length = 213 Score = 140 bits (352), Expect = 5e-33 Identities = 79/143 (55%), Positives = 99/143 (69%), Gaps = 9/143 (6%) Query: 1 MGGDNPEVSERA-NSSKFDPTKSPVLSDEDSDLDFHINKLEQQSKVRNKGHGKPREKSIA 59 MGGDNPEV ++A NSSKF+ KSPV SDEDSDLDF I+KLEQQSKV+N GHGKPREKSI Sbjct: 63 MGGDNPEVGKKARNSSKFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSII 122 Query: 60 DEKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDA 119 DEKFFQLSEMEAYLENR++ ++ D DD+ +S + K+ V E+ ED Sbjct: 123 DEKFFQLSEMEAYLENREKEEERKDDNDDESGKSSRNVNNKDFFDPV-------ESDEDI 175 Query: 120 GVSHVKK-NSDEVKSSFKKRQEK 141 H + S+++ KK+Q+K Sbjct: 176 ASDHDDELGSNKMMKLLKKKQKK 198 Score = 35.8 bits (81), Expect = 0.13 Identities = 34/137 (24%), Positives = 61/137 (44%), Gaps = 6/137 (4%) Query: 430 WRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQE 489 W+ E E EE Q+ EE E E QE+ E +QE+EE + E +K Sbjct: 22 WQIVELGEESEE--QECEEDGSETETGGQEDLEDLQEEEEVSDMGGDN-PEVGKKARNSS 78 Query: 490 KLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQE---EK 546 K ++ ++ E+ + EQ+ K+Q R++ + E+ +L + E E Sbjct: 79 KFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLEN 138 Query: 547 MQEQEVRLQELEERLGK 563 +++E R + ++ GK Sbjct: 139 REKEEERKDDNDDESGK 155 >gi|169208458 PREDICTED: similar to golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 432 Score = 139 bits (350), Expect = 8e-33 Identities = 87/237 (36%), Positives = 150/237 (63%), Gaps = 30/237 (12%) Query: 231 ESEKSEIQLNVKDLKRKL-----ERAQLLLPQ--------QQLQVEADRLGKELQSVSAK 277 E +K EI L V+ L R L + A+ L PQ +QLQ E + L KEL+SV + Sbjct: 121 EEKKHEIHL-VQKLGRSLFKLKNQTAEPLAPQPPAGPSKVEQLQDETNHLRKELESVGRQ 179 Query: 278 LQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQ 337 LQA+VE N++ +LLN++QEE++ QEE+++EQEE++CEQE ++ EQEE++ QEE++ EQ Sbjct: 180 LQAEVENNQMLSLLNRRQEERLREQEERLREQEERLCEQEERLCEQEERLREQEERLCEQ 239 Query: 338 E-----EKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWR 392 E E++ E+ +K+ +QE + EQE + + E++ + E++ EQ E++++Q+E +W+ Sbjct: 240 EKLPGQERLLEEVEKLLKQERRQEEQERLL--ERERLLDEVEELLEQ-ERLRQQDERLWQ 296 Query: 393 QE-----EKIREQE---EKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEE 441 QE E++RE E E E ++ Q + R E++ + + + E++++ELE+ Sbjct: 297 QETLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELEK 353 Score = 108 bits (270), Expect = 2e-23 Identities = 78/266 (29%), Positives = 145/266 (54%), Gaps = 19/266 (7%) Query: 330 QEEKMHEQEEKIREQEDKMWRQEEKIREQE-EKIREQEEKMWRQEEKIREQDEKIQEQEE 388 +EEK HE K+ R K++ Q E + Q + E+++++ ++++ E Sbjct: 120 KEEKKHEIH-----LVQKLGRSLFKLKNQTAEPLAPQPPAGPSKVEQLQDETNHLRKELE 174 Query: 389 EMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEE 448 + RQ + E + RQE+++REQ+E++REQEE + QEE++ E EE +++QEE Sbjct: 175 SVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLCEQEERLCEQEERLREQEE 234 Query: 449 KLREVE-----EKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEE 503 +L E E E++ EE EK+ +QE + Q ++E++ E+E E+LL+Q E++ +Q+E Sbjct: 235 RLCEQEKLPGQERLLEEVEKLLKQERR-QEEQERLLERERLLDEVEELLEQ-ERLRQQDE 292 Query: 504 KMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGK 563 ++W+QE + E+++E E ++ E + EQ E++ + +LE+++ + Sbjct: 293 RLWQQE--TLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKE 350 Query: 564 LGQKAELLGGAGRESGSQRLPTLTPI 589 L E GGA GS+ P+ Sbjct: 351 L----EKSGGAEEPRGSESAAAARPV 372 Score = 90.1 bits (222), Expect = 6e-18 Identities = 66/231 (28%), Positives = 126/231 (54%), Gaps = 32/231 (13%) Query: 382 KIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQD------------EKIREQEEEM 429 ++ E + R ++ ++ E +K+ R K++ Q K+ + ++E Sbjct: 107 QLTENINSLVRTSKEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPQPPAGPSKVEQLQDET 166 Query: 430 WRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQ- 488 +++ + +Q + E + + + +EE+++EQEE+++ QEE++ EQEE+ Q Sbjct: 167 NHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLCEQEERLCEQE 226 Query: 489 EKLLKQEEKIWEQE-----EKMWRQEEKMWEQEEKMQEQEEKMQR-----------QEEK 532 E+L +QEE++ EQE E++ + EK+ +QE + +EQE ++R ++E+ Sbjct: 227 ERLREQEERLCEQEKLPGQERLLEEVEKLLKQERRQEEQERLLERERLLDEVEELLEQER 286 Query: 533 MREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRL 583 +R+Q+ RLWQQ E ++E E RL+EL ER+ +LG +A A SG + L Sbjct: 287 LRQQDERLWQQ-ETLRELE-RLREL-ERMLELGWEALYEQRAEPRSGFEEL 334 Score = 48.5 bits (114), Expect = 2e-05 Identities = 46/184 (25%), Positives = 93/184 (50%), Gaps = 22/184 (11%) Query: 193 EKLTKERDAPSLELYRNTITDEELKEKNAELQEKL-RLVESEKSEIQLNVKDLKRKLERA 251 E+L ++ + + R +E L E+ L+E+ RL E EK Q +R LE Sbjct: 199 ERLREQEERLREQEERLCEQEERLCEQEERLREQEERLCEQEKLPGQ------ERLLEEV 252 Query: 252 QLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEE 311 + LL Q++ Q E +RL E + + +++ +E+ L +QQ+E++W Q+E ++E E Sbjct: 253 EKLLKQERRQEEQERL-LERERLLDEVEELLEQERL-----RQQDERLW-QQETLRELE- 304 Query: 312 KMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWR 371 ++RE E + E ++EQ + R +++ + + + E++++E E+ Sbjct: 305 -------RLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELEKSGGA 357 Query: 372 QEEK 375 +E + Sbjct: 358 EEPR 361 >gi|154937324 hypothetical protein LOC440295 [Homo sapiens] Length = 432 Score = 139 bits (350), Expect = 8e-33 Identities = 87/237 (36%), Positives = 150/237 (63%), Gaps = 30/237 (12%) Query: 231 ESEKSEIQLNVKDLKRKL-----ERAQLLLPQ--------QQLQVEADRLGKELQSVSAK 277 E +K EI L V+ L R L + A+ L PQ +QLQ E + L KEL+SV + Sbjct: 121 EEKKHEIHL-VQKLGRSLFKLKNQTAEPLAPQPPAGPSKVEQLQDETNHLRKELESVGRQ 179 Query: 278 LQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQ 337 LQA+VE N++ +LLN++QEE++ QEE+++EQEE++CEQE ++ EQEE++ QEE++ EQ Sbjct: 180 LQAEVENNQMLSLLNRRQEERLREQEERLREQEERLCEQEERLCEQEERLREQEERLCEQ 239 Query: 338 E-----EKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWR 392 E E++ E+ +K+ +QE + EQE + + E++ + E++ EQ E++++Q+E +W+ Sbjct: 240 EKLPGQERLLEEVEKLLKQERRQEEQERLL--ERERLLDEVEELLEQ-ERLRQQDERLWQ 296 Query: 393 QE-----EKIREQE---EKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEE 441 QE E++RE E E E ++ Q + R E++ + + + E++++ELE+ Sbjct: 297 QETLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELEK 353 Score = 108 bits (270), Expect = 2e-23 Identities = 78/266 (29%), Positives = 145/266 (54%), Gaps = 19/266 (7%) Query: 330 QEEKMHEQEEKIREQEDKMWRQEEKIREQE-EKIREQEEKMWRQEEKIREQDEKIQEQEE 388 +EEK HE K+ R K++ Q E + Q + E+++++ ++++ E Sbjct: 120 KEEKKHEIH-----LVQKLGRSLFKLKNQTAEPLAPQPPAGPSKVEQLQDETNHLRKELE 174 Query: 389 EMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEE 448 + RQ + E + RQE+++REQ+E++REQEE + QEE++ E EE +++QEE Sbjct: 175 SVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLCEQEERLCEQEERLREQEE 234 Query: 449 KLREVE-----EKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEE 503 +L E E E++ EE EK+ +QE + Q ++E++ E+E E+LL+Q E++ +Q+E Sbjct: 235 RLCEQEKLPGQERLLEEVEKLLKQERR-QEEQERLLERERLLDEVEELLEQ-ERLRQQDE 292 Query: 504 KMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGK 563 ++W+QE + E+++E E ++ E + EQ E++ + +LE+++ + Sbjct: 293 RLWQQE--TLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKE 350 Query: 564 LGQKAELLGGAGRESGSQRLPTLTPI 589 L E GGA GS+ P+ Sbjct: 351 L----EKSGGAEEPRGSESAAAARPV 372 Score = 90.1 bits (222), Expect = 6e-18 Identities = 66/231 (28%), Positives = 126/231 (54%), Gaps = 32/231 (13%) Query: 382 KIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQD------------EKIREQEEEM 429 ++ E + R ++ ++ E +K+ R K++ Q K+ + ++E Sbjct: 107 QLTENINSLVRTSKEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPQPPAGPSKVEQLQDET 166 Query: 430 WRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQ- 488 +++ + +Q + E + + + +EE+++EQEE+++ QEE++ EQEE+ Q Sbjct: 167 NHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLCEQEERLCEQE 226 Query: 489 EKLLKQEEKIWEQE-----EKMWRQEEKMWEQEEKMQEQEEKMQR-----------QEEK 532 E+L +QEE++ EQE E++ + EK+ +QE + +EQE ++R ++E+ Sbjct: 227 ERLREQEERLCEQEKLPGQERLLEEVEKLLKQERRQEEQERLLERERLLDEVEELLEQER 286 Query: 533 MREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRL 583 +R+Q+ RLWQQ E ++E E RL+EL ER+ +LG +A A SG + L Sbjct: 287 LRQQDERLWQQ-ETLRELE-RLREL-ERMLELGWEALYEQRAEPRSGFEEL 334 Score = 48.5 bits (114), Expect = 2e-05 Identities = 46/184 (25%), Positives = 93/184 (50%), Gaps = 22/184 (11%) Query: 193 EKLTKERDAPSLELYRNTITDEELKEKNAELQEKL-RLVESEKSEIQLNVKDLKRKLERA 251 E+L ++ + + R +E L E+ L+E+ RL E EK Q +R LE Sbjct: 199 ERLREQEERLREQEERLCEQEERLCEQEERLREQEERLCEQEKLPGQ------ERLLEEV 252 Query: 252 QLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEE 311 + LL Q++ Q E +RL E + + +++ +E+ L +QQ+E++W Q+E ++E E Sbjct: 253 EKLLKQERRQEEQERL-LERERLLDEVEELLEQERL-----RQQDERLW-QQETLRELE- 304 Query: 312 KMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWR 371 ++RE E + E ++EQ + R +++ + + + E++++E E+ Sbjct: 305 -------RLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELEKSGGA 357 Query: 372 QEEK 375 +E + Sbjct: 358 EEPR 361 >gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sapiens] Length = 1293 Score = 134 bits (337), Expect = 3e-31 Identities = 111/455 (24%), Positives = 231/455 (50%), Gaps = 70/455 (15%) Query: 193 EKLTKERDAPSL--------------ELYRNTITDEELKEKNAELQEKLRLVESEKSEIQ 238 E+LT++++ +L + Y + ++ +++ Q++L L+ + ++ Sbjct: 602 ERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTLK 661 Query: 239 LNVKDLKRKLERAQLLLPQQQLQVEADRLGK--ELQSVSAKLQAQVEENELWNLL----- 291 + + D Q ++P V G ELQ +++ E +W+L Sbjct: 662 MRISD--------QNIIPSVTRSVSVPDTGSIWELQPTASQPTVW-EGGSVWDLPLDTTT 712 Query: 292 -NQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQ--EDKM 348 E+ ++ K + E++ E E++ + +EE+ RQEE +QEE +R Q E++ Sbjct: 713 PGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERK 772 Query: 349 WRQEEKI--REQEEKIREQEEKMWRQEEKIREQ--DEKIQEQEEEMWRQEEKIREQEEKR 404 R+EE++ R+QEE +R Q E QE +R Q +E+ Q+QEE + R EE+ RE+EE+ Sbjct: 773 RREEEELARRKQEEALRRQRE----QEIALRRQREEEERQQQEEALRRLEERRREEEER- 827 Query: 405 QEKMWRQEKKMREQDEKIREQEEE--MWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462 R+Q+E +R+QEEE W +EE+ E + +++ ++ E +++ EEE Sbjct: 828 -----------RKQEELLRKQEEEAAKWAREEE--EAQRRLEENRLRMEEEAARLRHEEE 874 Query: 463 KMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEK---M 519 + + +E ++QRQ+E +++++++ +L +Q+++ +Q +M W Q+ Sbjct: 875 ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQ--QQLAQMKLPSSSTWGQQSNTTAC 932 Query: 520 QEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESG 579 Q Q + +K+ E+ R ++E++ Q++E+ ++ L+++ + QK G + SG Sbjct: 933 QSQATLSLAEIQKLEEERERQLREEQRRQQREL-MKALQQQQQQQQQKLSGWGNVSKPSG 991 Query: 580 SQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQ 614 + + +E++ +EA+ +Q+QQ + H Q Sbjct: 992 TTK-------SLLEIQQEEARQMQKQQQQQQQHQQ 1019 Score = 110 bits (275), Expect = 4e-24 Identities = 82/258 (31%), Positives = 146/258 (56%), Gaps = 20/258 (7%) Query: 378 EQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIR 437 +Q EK + + E R+E ++R + E+ + K RQE+ R+Q+E +R Q+EE E K R Sbjct: 721 QQLEKAKAAKLEQERREAEMRAKREEEERK--RQEELRRQQEEILRRQQEE----ERKRR 774 Query: 438 ELEEMMQ-DQEEKLR-----EVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKL 491 E EE+ + QEE LR E+ + Q EEE+ Q+QEE ++R EE+ +E+EE+ ++E L Sbjct: 775 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 834 Query: 492 LKQEEKI--W--EQEEKMWRQEE---KMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQE 544 KQEE+ W E+EE R EE +M E+ +++ +EE+ +R+E +++ Q+ L +Q Sbjct: 835 RKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQK-ELMRQR 893 Query: 545 EKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQ 604 ++ QE RLQ+ +++ K G++S + + + E++ E + +Q Sbjct: 894 QQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQ 953 Query: 605 QQDHYRGHLQQYVAAYQQ 622 ++ R ++ + A QQ Sbjct: 954 LREEQRRQQRELMKALQQ 971 Score = 97.4 bits (241), Expect = 4e-20 Identities = 72/245 (29%), Positives = 133/245 (54%), Gaps = 22/245 (8%) Query: 395 EKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMM---QDQEEKLR 451 E++++ E+ + K+ E++ RE + + + +EEE RQEE R+ EE++ Q++E K R Sbjct: 718 EQLQQLEKAKAAKL---EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 774 Query: 452 EVEE---KMQEEEEKMQEQEE---KIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKM 505 E EE + QEE + Q ++E + QR+EE+ Q+QEE R E+ ++EE+ +QEE + Sbjct: 775 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 834 Query: 506 WRQEEK--MWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGK 563 +QEE+ W +EE +E + +++ +M E+ RL +EE+ + +E+ +Q +E + + Sbjct: 835 RKQEEEAAKWAREE--EEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQ 892 Query: 564 LGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQQYVAAYQQL 623 Q+ E L ++ Q+L Q++L S Q + +A Q+L Sbjct: 893 RQQQQEALRRLQQQQQQQQL------AQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKL 946 Query: 624 ASGKE 628 +E Sbjct: 947 EEERE 951 >gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sapiens] Length = 1320 Score = 134 bits (337), Expect = 3e-31 Identities = 111/455 (24%), Positives = 231/455 (50%), Gaps = 70/455 (15%) Query: 193 EKLTKERDAPSL--------------ELYRNTITDEELKEKNAELQEKLRLVESEKSEIQ 238 E+LT++++ +L + Y + ++ +++ Q++L L+ + ++ Sbjct: 629 ERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTLK 688 Query: 239 LNVKDLKRKLERAQLLLPQQQLQVEADRLGK--ELQSVSAKLQAQVEENELWNLL----- 291 + + D Q ++P V G ELQ +++ E +W+L Sbjct: 689 MRISD--------QNIIPSVTRSVSVPDTGSIWELQPTASQPTVW-EGGSVWDLPLDTTT 739 Query: 292 -NQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQ--EDKM 348 E+ ++ K + E++ E E++ + +EE+ RQEE +QEE +R Q E++ Sbjct: 740 PGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERK 799 Query: 349 WRQEEKI--REQEEKIREQEEKMWRQEEKIREQ--DEKIQEQEEEMWRQEEKIREQEEKR 404 R+EE++ R+QEE +R Q E QE +R Q +E+ Q+QEE + R EE+ RE+EE+ Sbjct: 800 RREEEELARRKQEEALRRQRE----QEIALRRQREEEERQQQEEALRRLEERRREEEER- 854 Query: 405 QEKMWRQEKKMREQDEKIREQEEE--MWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462 R+Q+E +R+QEEE W +EE+ E + +++ ++ E +++ EEE Sbjct: 855 -----------RKQEELLRKQEEEAAKWAREEE--EAQRRLEENRLRMEEEAARLRHEEE 901 Query: 463 KMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEK---M 519 + + +E ++QRQ+E +++++++ +L +Q+++ +Q +M W Q+ Sbjct: 902 ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQ--QQLAQMKLPSSSTWGQQSNTTAC 959 Query: 520 QEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESG 579 Q Q + +K+ E+ R ++E++ Q++E+ ++ L+++ + QK G + SG Sbjct: 960 QSQATLSLAEIQKLEEERERQLREEQRRQQREL-MKALQQQQQQQQQKLSGWGNVSKPSG 1018 Query: 580 SQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQ 614 + + +E++ +EA+ +Q+QQ + H Q Sbjct: 1019 TTK-------SLLEIQQEEARQMQKQQQQQQQHQQ 1046 Score = 110 bits (275), Expect = 4e-24 Identities = 82/258 (31%), Positives = 146/258 (56%), Gaps = 20/258 (7%) Query: 378 EQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIR 437 +Q EK + + E R+E ++R + E+ + K RQE+ R+Q+E +R Q+EE E K R Sbjct: 748 QQLEKAKAAKLEQERREAEMRAKREEEERK--RQEELRRQQEEILRRQQEE----ERKRR 801 Query: 438 ELEEMMQ-DQEEKLR-----EVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKL 491 E EE+ + QEE LR E+ + Q EEE+ Q+QEE ++R EE+ +E+EE+ ++E L Sbjct: 802 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 861 Query: 492 LKQEEKI--W--EQEEKMWRQEE---KMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQE 544 KQEE+ W E+EE R EE +M E+ +++ +EE+ +R+E +++ Q+ L +Q Sbjct: 862 RKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQK-ELMRQR 920 Query: 545 EKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQ 604 ++ QE RLQ+ +++ K G++S + + + E++ E + +Q Sbjct: 921 QQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQ 980 Query: 605 QQDHYRGHLQQYVAAYQQ 622 ++ R ++ + A QQ Sbjct: 981 LREEQRRQQRELMKALQQ 998 Score = 97.4 bits (241), Expect = 4e-20 Identities = 72/245 (29%), Positives = 133/245 (54%), Gaps = 22/245 (8%) Query: 395 EKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMM---QDQEEKLR 451 E++++ E+ + K+ E++ RE + + + +EEE RQEE R+ EE++ Q++E K R Sbjct: 745 EQLQQLEKAKAAKL---EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 801 Query: 452 EVEE---KMQEEEEKMQEQEE---KIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKM 505 E EE + QEE + Q ++E + QR+EE+ Q+QEE R E+ ++EE+ +QEE + Sbjct: 802 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 861 Query: 506 WRQEEK--MWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGK 563 +QEE+ W +EE +E + +++ +M E+ RL +EE+ + +E+ +Q +E + + Sbjct: 862 RKQEEEAAKWAREE--EEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQ 919 Query: 564 LGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQQYVAAYQQL 623 Q+ E L ++ Q+L Q++L S Q + +A Q+L Sbjct: 920 RQQQQEALRRLQQQQQQQQL------AQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKL 973 Query: 624 ASGKE 628 +E Sbjct: 974 EEERE 978 >gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sapiens] Length = 1299 Score = 134 bits (337), Expect = 3e-31 Identities = 111/455 (24%), Positives = 231/455 (50%), Gaps = 70/455 (15%) Query: 193 EKLTKERDAPSL--------------ELYRNTITDEELKEKNAELQEKLRLVESEKSEIQ 238 E+LT++++ +L + Y + ++ +++ Q++L L+ + ++ Sbjct: 608 ERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTLK 667 Query: 239 LNVKDLKRKLERAQLLLPQQQLQVEADRLGK--ELQSVSAKLQAQVEENELWNLL----- 291 + + D Q ++P V G ELQ +++ E +W+L Sbjct: 668 MRISD--------QNIIPSVTRSVSVPDTGSIWELQPTASQPTVW-EGGSVWDLPLDTTT 718 Query: 292 -NQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQ--EDKM 348 E+ ++ K + E++ E E++ + +EE+ RQEE +QEE +R Q E++ Sbjct: 719 PGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERK 778 Query: 349 WRQEEKI--REQEEKIREQEEKMWRQEEKIREQ--DEKIQEQEEEMWRQEEKIREQEEKR 404 R+EE++ R+QEE +R Q E QE +R Q +E+ Q+QEE + R EE+ RE+EE+ Sbjct: 779 RREEEELARRKQEEALRRQRE----QEIALRRQREEEERQQQEEALRRLEERRREEEER- 833 Query: 405 QEKMWRQEKKMREQDEKIREQEEE--MWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462 R+Q+E +R+QEEE W +EE+ E + +++ ++ E +++ EEE Sbjct: 834 -----------RKQEELLRKQEEEAAKWAREEE--EAQRRLEENRLRMEEEAARLRHEEE 880 Query: 463 KMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEK---M 519 + + +E ++QRQ+E +++++++ +L +Q+++ +Q +M W Q+ Sbjct: 881 ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQ--QQLAQMKLPSSSTWGQQSNTTAC 938 Query: 520 QEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESG 579 Q Q + +K+ E+ R ++E++ Q++E+ ++ L+++ + QK G + SG Sbjct: 939 QSQATLSLAEIQKLEEERERQLREEQRRQQREL-MKALQQQQQQQQQKLSGWGNVSKPSG 997 Query: 580 SQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQ 614 + + +E++ +EA+ +Q+QQ + H Q Sbjct: 998 TTK-------SLLEIQQEEARQMQKQQQQQQQHQQ 1025 Score = 110 bits (275), Expect = 4e-24 Identities = 82/258 (31%), Positives = 146/258 (56%), Gaps = 20/258 (7%) Query: 378 EQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIR 437 +Q EK + + E R+E ++R + E+ + K RQE+ R+Q+E +R Q+EE E K R Sbjct: 727 QQLEKAKAAKLEQERREAEMRAKREEEERK--RQEELRRQQEEILRRQQEE----ERKRR 780 Query: 438 ELEEMMQ-DQEEKLR-----EVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKL 491 E EE+ + QEE LR E+ + Q EEE+ Q+QEE ++R EE+ +E+EE+ ++E L Sbjct: 781 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 840 Query: 492 LKQEEKI--W--EQEEKMWRQEE---KMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQE 544 KQEE+ W E+EE R EE +M E+ +++ +EE+ +R+E +++ Q+ L +Q Sbjct: 841 RKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQK-ELMRQR 899 Query: 545 EKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQ 604 ++ QE RLQ+ +++ K G++S + + + E++ E + +Q Sbjct: 900 QQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQ 959 Query: 605 QQDHYRGHLQQYVAAYQQ 622 ++ R ++ + A QQ Sbjct: 960 LREEQRRQQRELMKALQQ 977 Score = 97.4 bits (241), Expect = 4e-20 Identities = 72/245 (29%), Positives = 133/245 (54%), Gaps = 22/245 (8%) Query: 395 EKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMM---QDQEEKLR 451 E++++ E+ + K+ E++ RE + + + +EEE RQEE R+ EE++ Q++E K R Sbjct: 724 EQLQQLEKAKAAKL---EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 780 Query: 452 EVEE---KMQEEEEKMQEQEE---KIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKM 505 E EE + QEE + Q ++E + QR+EE+ Q+QEE R E+ ++EE+ +QEE + Sbjct: 781 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 840 Query: 506 WRQEEK--MWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGK 563 +QEE+ W +EE +E + +++ +M E+ RL +EE+ + +E+ +Q +E + + Sbjct: 841 RKQEEEAAKWAREE--EEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQ 898 Query: 564 LGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQQYVAAYQQL 623 Q+ E L ++ Q+L Q++L S Q + +A Q+L Sbjct: 899 RQQQQEALRRLQQQQQQQQL------AQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKL 952 Query: 624 ASGKE 628 +E Sbjct: 953 EEERE 957 >gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapiens] Length = 1299 Score = 134 bits (337), Expect = 3e-31 Identities = 111/455 (24%), Positives = 231/455 (50%), Gaps = 70/455 (15%) Query: 193 EKLTKERDAPSL--------------ELYRNTITDEELKEKNAELQEKLRLVESEKSEIQ 238 E+LT++++ +L + Y + ++ +++ Q++L L+ + ++ Sbjct: 608 ERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTLK 667 Query: 239 LNVKDLKRKLERAQLLLPQQQLQVEADRLGK--ELQSVSAKLQAQVEENELWNLL----- 291 + + D Q ++P V G ELQ +++ E +W+L Sbjct: 668 MRISD--------QNIIPSVTRSVSVPDTGSIWELQPTASQPTVW-EGGSVWDLPLDTTT 718 Query: 292 -NQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQ--EDKM 348 E+ ++ K + E++ E E++ + +EE+ RQEE +QEE +R Q E++ Sbjct: 719 PGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERK 778 Query: 349 WRQEEKI--REQEEKIREQEEKMWRQEEKIREQ--DEKIQEQEEEMWRQEEKIREQEEKR 404 R+EE++ R+QEE +R Q E QE +R Q +E+ Q+QEE + R EE+ RE+EE+ Sbjct: 779 RREEEELARRKQEEALRRQRE----QEIALRRQREEEERQQQEEALRRLEERRREEEER- 833 Query: 405 QEKMWRQEKKMREQDEKIREQEEE--MWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462 R+Q+E +R+QEEE W +EE+ E + +++ ++ E +++ EEE Sbjct: 834 -----------RKQEELLRKQEEEAAKWAREEE--EAQRRLEENRLRMEEEAARLRHEEE 880 Query: 463 KMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEK---M 519 + + +E ++QRQ+E +++++++ +L +Q+++ +Q +M W Q+ Sbjct: 881 ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQ--QQLAQMKLPSSSTWGQQSNTTAC 938 Query: 520 QEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESG 579 Q Q + +K+ E+ R ++E++ Q++E+ ++ L+++ + QK G + SG Sbjct: 939 QSQATLSLAEIQKLEEERERQLREEQRRQQREL-MKALQQQQQQQQQKLSGWGNVSKPSG 997 Query: 580 SQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQ 614 + + +E++ +EA+ +Q+QQ + H Q Sbjct: 998 TTK-------SLLEIQQEEARQMQKQQQQQQQHQQ 1025 Score = 110 bits (275), Expect = 4e-24 Identities = 82/258 (31%), Positives = 146/258 (56%), Gaps = 20/258 (7%) Query: 378 EQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIR 437 +Q EK + + E R+E ++R + E+ + K RQE+ R+Q+E +R Q+EE E K R Sbjct: 727 QQLEKAKAAKLEQERREAEMRAKREEEERK--RQEELRRQQEEILRRQQEE----ERKRR 780 Query: 438 ELEEMMQ-DQEEKLR-----EVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKL 491 E EE+ + QEE LR E+ + Q EEE+ Q+QEE ++R EE+ +E+EE+ ++E L Sbjct: 781 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 840 Query: 492 LKQEEKI--W--EQEEKMWRQEE---KMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQE 544 KQEE+ W E+EE R EE +M E+ +++ +EE+ +R+E +++ Q+ L +Q Sbjct: 841 RKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQK-ELMRQR 899 Query: 545 EKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQ 604 ++ QE RLQ+ +++ K G++S + + + E++ E + +Q Sbjct: 900 QQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQ 959 Query: 605 QQDHYRGHLQQYVAAYQQ 622 ++ R ++ + A QQ Sbjct: 960 LREEQRRQQRELMKALQQ 977 Score = 97.4 bits (241), Expect = 4e-20 Identities = 72/245 (29%), Positives = 133/245 (54%), Gaps = 22/245 (8%) Query: 395 EKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMM---QDQEEKLR 451 E++++ E+ + K+ E++ RE + + + +EEE RQEE R+ EE++ Q++E K R Sbjct: 724 EQLQQLEKAKAAKL---EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 780 Query: 452 EVEE---KMQEEEEKMQEQEE---KIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKM 505 E EE + QEE + Q ++E + QR+EE+ Q+QEE R E+ ++EE+ +QEE + Sbjct: 781 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 840 Query: 506 WRQEEK--MWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGK 563 +QEE+ W +EE +E + +++ +M E+ RL +EE+ + +E+ +Q +E + + Sbjct: 841 RKQEEEAAKWAREE--EEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQ 898 Query: 564 LGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQQYVAAYQQL 623 Q+ E L ++ Q+L Q++L S Q + +A Q+L Sbjct: 899 RQQQQEALRRLQQQQQQQQL------AQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKL 952 Query: 624 ASGKE 628 +E Sbjct: 953 EEERE 957 >gi|239745259 PREDICTED: hypothetical protein isoform 2 [Homo sapiens] Length = 432 Score = 133 bits (334), Expect = 6e-31 Identities = 85/237 (35%), Positives = 148/237 (62%), Gaps = 30/237 (12%) Query: 231 ESEKSEIQLNVKDLKRKL-----ERAQLLLPQ--------QQLQVEADRLGKELQSVSAK 277 E +K EI L V+ L R L + A+ L P+ +QLQ E + L KEL+SV + Sbjct: 121 EEKKHEIHL-VQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQ 179 Query: 278 LQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQ 337 LQA+VE N++ +LLN++QEE++ QEE+++EQEE++ EQE ++ EQEE++ QEE++ EQ Sbjct: 180 LQAEVENNQMLSLLNRRQEERLREQEERLREQEERLHEQEERLCEQEERLCEQEERLCEQ 239 Query: 338 E-----EKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWR 392 E E++ E+ +K+ QE + EQE + + E++ + E++ EQ E++++Q+E +W+ Sbjct: 240 EKLPGQERLLEEVEKLLEQERRQEEQERLL--ERERLLDEVEELLEQ-ERLRQQDERLWQ 296 Query: 393 QE-----EKIREQE---EKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEE 441 QE E++RE E E E ++ Q + R E++ + + + E++++ELE+ Sbjct: 297 QETLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELEK 353 Score = 98.6 bits (244), Expect = 2e-20 Identities = 80/285 (28%), Positives = 154/285 (54%), Gaps = 35/285 (12%) Query: 258 QQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQE 317 Q L+ + L L S SA + +Q+ EN + +L+ +EEK + E + + K+ Sbjct: 85 QDLESQYQELAVALDSSSAII-SQLTEN-INSLVRTSKEEK--KHEIHLVQ---KLGRSL 137 Query: 318 LKIREQEEKMWRQE--------EKMHEQEEKIREQEDKMWRQEEKI-----------REQ 358 K++ Q + E E++ ++ +R++ + + RQ + R Q Sbjct: 138 FKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQ 197 Query: 359 EEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEE-KRQEKMWRQEKKMRE 417 EE++REQEE++ QEE++ EQ+E++ EQEE + QEE++ EQE+ QE++ + +K+ E Sbjct: 198 EERLREQEERLREQEERLHEQEERLCEQEERLCEQEERLCEQEKLPGQERLLEEVEKLLE 257 Query: 418 QDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEE-----EKMQEQEEKIQ 472 Q E+ +E++E + +E + E+EE++ ++E+LR+ +E++ ++E E+++E E ++ Sbjct: 258 Q-ERRQEEQERLLERERLLDEVEELL--EQERLRQQDERLWQQETLRELERLRELERMLE 314 Query: 473 RQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEE 517 E + EQ + + L E K Q E+ ++ EK EE Sbjct: 315 LGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELEKSGGAEE 359 Score = 93.2 bits (230), Expect = 7e-19 Identities = 67/231 (29%), Positives = 126/231 (54%), Gaps = 32/231 (13%) Query: 382 KIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQD------------EKIREQEEEM 429 ++ E + R ++ ++ E +K+ R K++ Q K+ + ++E Sbjct: 107 QLTENINSLVRTSKEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDET 166 Query: 430 WRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQ- 488 +++ + +Q + E + + + +EE+++EQEE+++ QEE++ EQEE+ Q Sbjct: 167 NHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLHEQEERLCEQE 226 Query: 489 EKLLKQEEKIWEQE-----EKMWRQEEKMWEQEEKMQEQEEKMQR-----------QEEK 532 E+L +QEE++ EQE E++ + EK+ EQE + +EQE ++R ++E+ Sbjct: 227 ERLCEQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLDEVEELLEQER 286 Query: 533 MREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRL 583 +R+Q+ RLWQQ E ++E E RL+EL ER+ +LG +A A SG + L Sbjct: 287 LRQQDERLWQQ-ETLRELE-RLREL-ERMLELGWEALYEQRAEPRSGFEEL 334 Score = 49.7 bits (117), Expect = 9e-06 Identities = 42/193 (21%), Positives = 98/193 (50%), Gaps = 12/193 (6%) Query: 195 LTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKL-ERAQL 253 L KE ++ +L ++ L N +E+LR E E + + + + +L E+ + Sbjct: 169 LRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLHEQEERLCEQEER 228 Query: 254 LLPQQQLQVEADRL-GKE--LQSVSAKLQAQVEENELWNLLNQQQ---EEKMWRQEEKIQ 307 L Q++ E ++L G+E L+ V L+ + + E LL +++ E + ++E+++ Sbjct: 229 LCEQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLDEVEELLEQERLR 288 Query: 308 EQEEKMCEQEL-----KIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKI 362 +Q+E++ +QE ++RE E + E ++EQ + R +++ + + + E+++ Sbjct: 289 QQDERLWQQETLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQV 348 Query: 363 REQEEKMWRQEEK 375 +E E+ +E + Sbjct: 349 KELEKSGGAEEPR 361 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.306 0.124 0.335 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 27,723,758 Number of Sequences: 37866 Number of extensions: 1722063 Number of successful extensions: 149353 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 1821 Number of HSP's successfully gapped in prelim test: 1227 Number of HSP's that attempted gapping in prelim test: 13119 Number of HSP's gapped (non-prelim): 31393 length of query: 655 length of database: 18,247,518 effective HSP length: 109 effective length of query: 546 effective length of database: 14,120,124 effective search space: 7709587704 effective search space used: 7709587704 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 43 (22.0 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.