Guide to the Human Genome
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Search of human proteins with 239745153

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
         (655 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239745153 PREDICTED: similar to Putative golgin subfamily A m...  1305   0.0  
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m...  1301   0.0  
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa...   527   e-149
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap...   526   e-149
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik...   526   e-149
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa...   513   e-145
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li...   424   e-118
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li...   419   e-117
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi...   319   4e-87
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]           229   8e-60
gi|239752551 PREDICTED: hypothetical protein [Homo sapiens]           222   7e-58
gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo sap...   183   5e-46
gi|148746195 trichohyalin [Homo sapiens]                              180   3e-45
gi|31317305 M-phase phosphoprotein 10 [Homo sapiens]                  176   5e-44
gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo sap...   155   1e-37
gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C...   155   1e-37
gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo sapi...   154   2e-37
gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo sapi...   152   1e-36
gi|221219020 NYD-SP11 protein [Homo sapiens]                          148   1e-35
gi|194097392 Golgi autoantigen, golgin subfamily a, 2 [Homo sapi...   143   4e-34
gi|169210281 PREDICTED: similar to M-phase phosphoprotein 10 (U3...   140   5e-33
gi|169210488 PREDICTED: similar to M-phase phosphoprotein 10 (U3...   140   5e-33
gi|169210051 PREDICTED: similar to M-phase phosphoprotein 10 (U3...   140   5e-33
gi|169208458 PREDICTED: similar to golgi autoantigen, golgin sub...   139   8e-33
gi|154937324 hypothetical protein LOC440295 [Homo sapiens]            139   8e-33
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap...   134   3e-31
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap...   134   3e-31
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap...   134   3e-31
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi...   134   3e-31
gi|239745259 PREDICTED: hypothetical protein isoform 2 [Homo sap...   133   6e-31

>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
           member 6-like protein 6 [Homo sapiens]
          Length = 655

 Score = 1305 bits (3376), Expect = 0.0
 Identities = 655/655 (100%), Positives = 655/655 (100%)

Query: 1   MGGDNPEVSERANSSKFDPTKSPVLSDEDSDLDFHINKLEQQSKVRNKGHGKPREKSIAD 60
           MGGDNPEVSERANSSKFDPTKSPVLSDEDSDLDFHINKLEQQSKVRNKGHGKPREKSIAD
Sbjct: 1   MGGDNPEVSERANSSKFDPTKSPVLSDEDSDLDFHINKLEQQSKVRNKGHGKPREKSIAD 60

Query: 61  EKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAG 120
           EKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAG
Sbjct: 61  EKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAG 120

Query: 121 VSHVKKNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETL 180
           VSHVKKNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETL
Sbjct: 121 VSHVKKNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETL 180

Query: 181 HFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLN 240
           HFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLN
Sbjct: 181 HFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLN 240

Query: 241 VKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMW 300
           VKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMW
Sbjct: 241 VKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMW 300

Query: 301 RQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEE 360
           RQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEE
Sbjct: 301 RQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEE 360

Query: 361 KIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDE 420
           KIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDE
Sbjct: 361 KIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDE 420

Query: 421 KIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQE 480
           KIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQE
Sbjct: 421 KIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQE 480

Query: 481 QEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRL 540
           QEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRL
Sbjct: 481 QEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRL 540

Query: 541 WQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQ 600
           WQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQ
Sbjct: 541 WQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQ 600

Query: 601 SLQQQQDHYRGHLQQYVAAYQQLASGKEALPSCSSRKLRAKRWLRWPTNSCRRPS 655
           SLQQQQDHYRGHLQQYVAAYQQLASGKEALPSCSSRKLRAKRWLRWPTNSCRRPS
Sbjct: 601 SLQQQQDHYRGHLQQYVAAYQQLASGKEALPSCSSRKLRAKRWLRWPTNSCRRPS 655


>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
           member 6-like protein 6 [Homo sapiens]
          Length = 655

 Score = 1301 bits (3366), Expect = 0.0
 Identities = 654/655 (99%), Positives = 654/655 (99%)

Query: 1   MGGDNPEVSERANSSKFDPTKSPVLSDEDSDLDFHINKLEQQSKVRNKGHGKPREKSIAD 60
           MGGDNPEVSERANSSKFDPTKSPVLSDEDSDLDFHINKLEQQSKVRNKGHGKPREKSIAD
Sbjct: 1   MGGDNPEVSERANSSKFDPTKSPVLSDEDSDLDFHINKLEQQSKVRNKGHGKPREKSIAD 60

Query: 61  EKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAG 120
           EKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAG
Sbjct: 61  EKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAG 120

Query: 121 VSHVKKNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETL 180
           VSHVKKNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETL
Sbjct: 121 VSHVKKNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETL 180

Query: 181 HFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLN 240
           HFDHAVRMGTYIEKLTKERDA SLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLN
Sbjct: 181 HFDHAVRMGTYIEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLN 240

Query: 241 VKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMW 300
           VKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMW
Sbjct: 241 VKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMW 300

Query: 301 RQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEE 360
           RQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEE
Sbjct: 301 RQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEE 360

Query: 361 KIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDE 420
           KIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDE
Sbjct: 361 KIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDE 420

Query: 421 KIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQE 480
           KIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQE
Sbjct: 421 KIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQE 480

Query: 481 QEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRL 540
           QEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRL
Sbjct: 481 QEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRL 540

Query: 541 WQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQ 600
           WQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQ
Sbjct: 541 WQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQ 600

Query: 601 SLQQQQDHYRGHLQQYVAAYQQLASGKEALPSCSSRKLRAKRWLRWPTNSCRRPS 655
           SLQQQQDHYRGHLQQYVAAYQQLASGKEALPSCSSRKLRAKRWLRWPTNSCRRPS
Sbjct: 601 SLQQQQDHYRGHLQQYVAAYQQLASGKEALPSCSSRKLRAKRWLRWPTNSCRRPS 655


>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 668

 Score =  527 bits (1357), Expect = e-149
 Identities = 306/472 (64%), Positives = 341/472 (72%), Gaps = 102/472 (21%)

Query: 191 YIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLER 250
           YIE+LTKERDA SLELYRNTITDEELKEKNA+LQEKL+LVESEKSEIQLNVK+LKRKLER
Sbjct: 194 YIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLER 253

Query: 251 AQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQE-- 308
           A+LLLPQQQLQ EAD LGKELQSVSAKLQAQVEENELWN LNQQQEEKMWRQEEKIQE  
Sbjct: 254 AKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWE 313

Query: 309 -----QEEKMCEQELKIREQEEKMWRQEE------------------------------- 332
                QEEK+ EQE KIREQEEKM RQEE                               
Sbjct: 314 EKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMW 373

Query: 333 -----------KMHEQE------------EKIREQED------KMWRQEEKIREQEEKIR 363
                      KMHEQE            EKIREQE       KMWRQEEKIREQEEKIR
Sbjct: 374 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 433

Query: 364 EQEEKMWRQEEKIREQDEKIQEQE-----EEMWRQEEKIREQEE---------------K 403
           EQE+KMWRQEEKI EQ EKI+E+E     EEMWRQEEKIREQEE               K
Sbjct: 434 EQEKKMWRQEEKIHEQ-EKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRK 492

Query: 404 RQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEK 463
           ++EK+WRQE+KM +Q+EKIREQEE+MWRQEEKIRE EE +++QEEK+RE EE MQE+EEK
Sbjct: 493 QEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEK 552

Query: 464 MQEQEEKIQ------RQEEKIQEQEEKTWRQ-EKLLKQEEKIWEQEEK-------MWRQE 509
           M EQEEK+Q      RQEEKI+EQEEK   Q EK+ +QEEKIWEQEEK       M  QE
Sbjct: 553 MGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQE 612

Query: 510 EKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERL 561
           EKMWEQEEKM EQEEKMQ QEEKMR QE ++W+QE ++++QE ++QE +E L
Sbjct: 613 EKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHL 664



 Score =  342 bits (876), Expect = 8e-94
 Identities = 219/512 (42%), Positives = 308/512 (60%), Gaps = 82/512 (16%)

Query: 66  LSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVK 125
           +++ E   +N K +   +  E +  E   + K+ K  L+R    LP  +   +A   H+ 
Sbjct: 214 ITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEA--DHLG 271

Query: 126 KNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQK--RPENSLLE-ETLHF 182
           K   E++S   K Q ++ E              W RL +   +K  R E  + E E    
Sbjct: 272 K---ELQSVSAKLQAQVEENEL-----------WNRLNQQQEEKMWRQEEKIQEWEEKIQ 317

Query: 183 DHAVRMGTYIEKLTKERDAPSLELYRNTITDEELKEKNA---ELQEKLRLVESEKSEIQL 239
           +   ++    EK+ ++ +    +       +E+++ +     E +EK+R +E    E + 
Sbjct: 318 EQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEE 377

Query: 240 NVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKM 299
            +++L+ K+   + +  Q++ + E +++ ++ +                    Q+QE KM
Sbjct: 378 KIRELEEKMHEQEKIREQEEKRQEEEKIREQEK-------------------RQEQEAKM 418

Query: 300 WRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQE----EKIREQEDKMWRQEEKI 355
           WRQEEKI+EQEEK       IREQE+KMWRQEEK+HEQE    E+ R+++++MWRQEEKI
Sbjct: 419 WRQEEKIREQEEK-------IREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKI 471

Query: 356 REQE------------EKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEK 403
           REQE            EKIR+QEEK+WRQEEK+ +Q+EKI+EQEE+MWRQEEKIREQEE 
Sbjct: 472 REQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEE- 530

Query: 404 RQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEK 463
                     K+REQ+EKIREQEE M  QEEK+ E EE MQ+Q EK+R  EEK++E+EEK
Sbjct: 531 ----------KIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQ-EKMRRQEEKIREQEEK 579

Query: 464 MQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQE 523
           ++EQ+EKI+ QEEKI EQEEK   QE++++      EQEEKMW QEEKM EQEEKMQEQE
Sbjct: 580 IREQKEKIREQEEKIWEQEEKIREQEEMMQ------EQEEKMWEQEEKMCEQEEKMQEQE 633

Query: 524 EKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQ 555
           EKM+RQEEKM EQEVRL QQEEKMQE +  L+
Sbjct: 634 EKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLE 665



 Score =  196 bits (499), Expect = 4e-50
 Identities = 144/466 (30%), Positives = 238/466 (51%), Gaps = 87/466 (18%)

Query: 21  KSPVLSDEDSDLDFHINKLE-----------QQSKVRNKGHGKPREKSIADEKFFQLSEM 69
           K  ++  E S++  ++ +L+           QQ       H     +S++ +   Q+ E 
Sbjct: 229 KLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEEN 288

Query: 70  EAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSD 129
           E +    +++  K W +++ ++E E+  Q +E   R       +E I             
Sbjct: 289 ELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIR-----EQEEKIR------------ 331

Query: 130 EVKSSFKKRQEKMNEKNYTFRKRVVI----KKPWLRLGEVTAQKRPENSLLEETLHFDHA 185
           E +   ++++E M EK    R++  +    ++   RL E+  +K  +   LEE +H    
Sbjct: 332 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEK 391

Query: 186 VR----MGTYIEKLTKE--RDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQL 239
           +R         EK+ ++  R     +++R      E +EK  E QEK    + EK   Q 
Sbjct: 392 IREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE-QEKKMWRQEEKIHEQE 450

Query: 240 NVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQ------ 293
            +++ +++ E+ ++   +++++ E + + ++ + +  + + + +E ++W    +      
Sbjct: 451 KIREEEKRQEQEEMWRQEEKIR-EQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEE 509

Query: 294 ---QQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEK---------- 340
              +QEEKMWRQEEKI+EQEEK+ EQE KIREQEE M  QEEKM EQEEK          
Sbjct: 510 KIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQ 569

Query: 341 -----------------IREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKI 383
                            IREQE+K+W QEEKIREQEE ++EQEEKMW QEEK+ EQ+EK+
Sbjct: 570 EEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKM 629

Query: 384 QEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEM 429
           QEQEE+M RQE           EKMW QE ++R+Q+EK++E +E +
Sbjct: 630 QEQEEKMRRQE-----------EKMWEQEVRLRQQEEKMQEHQEHL 664


>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
           sapiens]
          Length = 570

 Score =  526 bits (1356), Expect = e-149
 Identities = 288/388 (74%), Positives = 323/388 (83%), Gaps = 29/388 (7%)

Query: 191 YIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLER 250
           YIE+LTKERDA SLELYRNTITDEELKEKNA+LQEKL+LVESEKSEIQLNVK+LKRKLER
Sbjct: 182 YIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLER 241

Query: 251 AQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQE 310
           A+LLLPQQQLQ EAD LGKELQSVSAKLQAQVEENELWN LNQQQEEKMWRQEEKIQE+E
Sbjct: 242 AKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQERE 301

Query: 311 EKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIRE------QEEKIRE 364
           EK+ EQE KIREQEEKM RQEE M E+EEK+R QE+ MW +EEKIRE      ++EKIRE
Sbjct: 302 EKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIRE 361

Query: 365 QEE-------------------KMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEK-- 403
           QEE                   KMWRQEEKIREQ+EKI+EQEE M  QEEK+ EQEEK  
Sbjct: 362 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMW 421

Query: 404 -RQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462
            ++E+M  QE+KMR Q+EKIREQE+++  QEEKIRE EEMMQ+QEEK+ E E KM E+E 
Sbjct: 422 EQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEA 481

Query: 463 KMQEQEEKIQRQEEKIQEQEEKTWRQ-EKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQE 521
           KMQEQEEK++RQEEKI+EQE+K   Q EK+ +QEE + EQEEKMW QEEKM EQEEKMQE
Sbjct: 482 KMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 541

Query: 522 QEEKMQRQEEKMREQEVRLWQQEEKMQE 549
           QEEKM+RQEEKMREQEVRL QQEEKMQE
Sbjct: 542 QEEKMRRQEEKMREQEVRLRQQEEKMQE 569



 Score =  198 bits (504), Expect = 1e-50
 Identities = 145/429 (33%), Positives = 222/429 (51%), Gaps = 87/429 (20%)

Query: 21  KSPVLSDEDSDLDFHINKLE-----------QQSKVRNKGHGKPREKSIADEKFFQLSEM 69
           K  ++  E S++  ++ +L+           QQ       H     +S++ +   Q+ E 
Sbjct: 217 KLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEEN 276

Query: 70  EAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSD 129
           E +    +++  K W +++ ++E E+  Q +E   R                        
Sbjct: 277 ELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIR------------------------ 312

Query: 130 EVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMG 189
           E +   ++++E M EK    R++           E+  +K  +   LEE +H    +R  
Sbjct: 313 EQEEKMRRQEEMMWEKEEKMRRQE----------EMMWEKEEKIRELEEKMHEQEKIR-- 360

Query: 190 TYIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLE 249
              E+  K ++   +            +EK  E + K+   E +  E +  +++      
Sbjct: 361 ---EQEEKRQEEEKIRE----------QEKRQEQEAKMWRQEEKIREQEEKIRE------ 401

Query: 250 RAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQ 309
                  ++ +Q + +++G++      K+  Q EE        Q+QEEKM RQEEKI+EQ
Sbjct: 402 ------QEEMMQEQEEKMGEQ----EEKMWEQEEE-------MQEQEEKMRRQEEKIREQ 444

Query: 310 EEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKM 369
           E+K+ EQE KIREQEE M  QEEKM EQE K+ EQE KM  QEEK+R QEEKIREQE+K+
Sbjct: 445 EKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKI 504

Query: 370 WRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEM 429
             QEEKIREQ+E +QEQEE+MW QEEK+ EQEEK QE    QE+KMR Q+EK+REQE  +
Sbjct: 505 REQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE----QEEKMRRQEEKMREQEVRL 560

Query: 430 WRQEEKIRE 438
            +QEEK++E
Sbjct: 561 RQQEEKMQE 569


>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
           protein 6 [Homo sapiens]
          Length = 724

 Score =  526 bits (1355), Expect = e-149
 Identities = 303/467 (64%), Positives = 337/467 (72%), Gaps = 97/467 (20%)

Query: 191 YIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLER 250
           YIE+LTKERDA SLELYRNTITDEELKEKNA+LQEKL+LVESEKSEIQLNVK+LKRKLER
Sbjct: 255 YIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLER 314

Query: 251 AQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQE-- 308
           A+LLLPQQQLQ EAD LGKELQSVSAKLQAQVEENELWN LNQQQEEKMWRQEEKIQE  
Sbjct: 315 AKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWE 374

Query: 309 -----QEEKMCEQELKIREQEEKMWRQEE------------------------------- 332
                QEEK+ EQE KIREQEEKM RQEE                               
Sbjct: 375 EKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMW 434

Query: 333 -----------KMHEQE------------EKIREQED------KMWRQEEKIREQEEKIR 363
                      KMHEQE            EKIREQE       KMWRQEEKIREQEEKIR
Sbjct: 435 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 494

Query: 364 EQEEKMWRQEEKIREQDEKIQEQE-----EEMWRQEEKIREQEE---------------- 402
           EQEEKMWRQEEKI EQ EKI+E+E     EEMWRQEEKIREQEE                
Sbjct: 495 EQEEKMWRQEEKIHEQ-EKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIR 553

Query: 403 KRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462
           K++EKMWRQE+KM +Q+EKIREQEE++WRQEEKIRE EE +++QEEK+RE EE  QE+EE
Sbjct: 554 KQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEE 613

Query: 463 KMQEQEEKIQRQEEKIQEQEEKTWRQE--------KLLKQEEKIWEQEEKMWRQEEKMWE 514
           KM EQEEK+  QEEK+QEQEEK  RQE        K+ +QEEKI EQEE M  QEEKMWE
Sbjct: 614 KMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWE 673

Query: 515 QEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERL 561
           QEEKM EQEEKMQ QEEKMR QE ++W+QE ++++QE ++QE +E L
Sbjct: 674 QEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHL 720



 Score =  325 bits (834), Expect = 6e-89
 Identities = 206/493 (41%), Positives = 297/493 (60%), Gaps = 72/493 (14%)

Query: 66  LSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVK 125
           +++ E   +N K +   +  E +  E   + K+ K  L+R    LP  +   +A   H+ 
Sbjct: 275 ITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEA--DHLG 332

Query: 126 KNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQK--RPENSLLE-ETLHF 182
           K   E++S   K Q ++ E              W RL +   +K  R E  + E E    
Sbjct: 333 K---ELQSVSAKLQAQVEENEL-----------WNRLNQQQEEKMWRQEEKIQEWEEKIQ 378

Query: 183 DHAVRMGTYIEKLTKERDAPSLELYRNTITDEELKEKNA---ELQEKLRLVESEKSEIQL 239
           +   ++    EK+ ++ +    +       +E+++ +     E +EK+R  E    E + 
Sbjct: 379 EQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 438

Query: 240 NVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKM 299
            +++L+ K+   + +  Q++ + E +++ ++ +                    Q+QE KM
Sbjct: 439 KIRELEEKMHEQEKIREQEEKRQEEEKIREQEK-------------------RQEQEAKM 479

Query: 300 WRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIRE------------QEDK 347
           WRQEEKI+EQEEK       IREQEEKMWRQEEK+HEQE KIRE            QE+K
Sbjct: 480 WRQEEKIREQEEK-------IREQEEKMWRQEEKIHEQE-KIREEEKRQEQEEMWRQEEK 531

Query: 348 M------WRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQE 401
           +      WRQ+EKI EQEEKIR+QEEKMWRQEEK+ +Q+EKI+EQEE++WRQEEKIREQE
Sbjct: 532 IREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQE 591

Query: 402 EKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEE 461
           EK +E    QE+K+REQ+E  +EQEE+M  QEEK+ E EE MQ+QEEK+R  EEK++E+E
Sbjct: 592 EKIRE----QEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQE 647

Query: 462 EKMQEQEEKIQRQEEKIQEQEEKTWRQ-EKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQ 520
           +K++EQEEKI+ QEE +QEQEEK W Q EK+ +QEEK+ EQEEKM RQEEKMWEQE +++
Sbjct: 648 KKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLR 707

Query: 521 EQEEKMQRQEEKM 533
           +QEEKMQ  +E +
Sbjct: 708 QQEEKMQEHQEHL 720



 Score =  249 bits (635), Expect = 7e-66
 Identities = 167/476 (35%), Positives = 268/476 (56%), Gaps = 61/476 (12%)

Query: 21  KSPVLSDEDSDLDFHINKLE-----------QQSKVRNKGHGKPREKSIADEKFFQLSEM 69
           K  ++  E S++  ++ +L+           QQ       H     +S++ +   Q+ E 
Sbjct: 290 KLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEEN 349

Query: 70  EAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSD 129
           E +    +++  K W +++ ++E E+  Q +E   R       +E I             
Sbjct: 350 ELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIR-----EQEEKIR------------ 392

Query: 130 EVKSSFKKRQEKMNEKNYTFRKRVVI----KKPWLRLGEVTAQKRPENSLLEETLHFDHA 185
           E +   ++++E M EK    R++  +    ++   R  E+  +K  +   LEE +H    
Sbjct: 393 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEK 452

Query: 186 VRMGTYIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLK 245
           +R     E+  K ++   +            +EK  E + K+   E +  E +  +++ +
Sbjct: 453 IR-----EQEEKRQEEEKIRE----------QEKRQEQEAKMWRQEEKIREQEEKIREQE 497

Query: 246 RKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQ--QQEEKMWRQE 303
            K+ R +  + +Q+ ++  +   +E + +  + +   E+ E+W    +  +QEEK+ +QE
Sbjct: 498 EKMWRQEEKIHEQE-KIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQE 556

Query: 304 EKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIR 363
           EK+  QEEKM +QE KIREQEEK+WRQEEK+ EQEEKIRE       QEEKIREQEE  +
Sbjct: 557 EKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIRE-------QEEKIREQEEMTQ 609

Query: 364 EQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIR 423
           EQEEKM  QEEK+ EQ+EK+QEQEE+M RQEEKIREQE+K +E    QE+K+REQ+E ++
Sbjct: 610 EQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIRE----QEEKIREQEEMMQ 665

Query: 424 EQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQ 479
           EQEE+MW QEEK+ E EE MQ+QEEK+R  EEKM E+E ++++QEEK+Q  +E ++
Sbjct: 666 EQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLE 721


>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 750

 Score =  513 bits (1320), Expect = e-145
 Identities = 290/496 (58%), Positives = 360/496 (72%), Gaps = 58/496 (11%)

Query: 191 YIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLER 250
           YIE+LTKERDA SLELYRNTITDEELKEKNA+LQEKL+LVESEKSEIQLNVK+LKRKLER
Sbjct: 194 YIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLER 253

Query: 251 AQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQ-------E 303
           A+LLLPQQQLQ EAD LGKELQSVSAKLQAQVEENELWN LNQQQEEKMWRQ       E
Sbjct: 254 AKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWE 313

Query: 304 EKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIR------- 356
           EKIQEQEEK+ EQE KIREQEEKM RQEE M E+EEK+R QE+ MW +EEK+R       
Sbjct: 314 EKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMW 373

Query: 357 EQEEKIREQEEKMWRQEEKIREQDEKI-------------------------QEQEEEMW 391
           E+EEK+R QEE MW +EEKIRE +EK+                         QEQE +MW
Sbjct: 374 EKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMW 433

Query: 392 RQEEKIREQEEK---RQEKMWRQEKKMREQDEKIREQE-----EEMWRQEEKIRELEEMM 443
           RQEEKIREQEEK   +++KMWRQE+K+ EQ EKIRE+E     EEMWRQEEKI E EE+ 
Sbjct: 434 RQEEKIREQEEKIREQEKKMWRQEEKIHEQ-EKIREEEKRQEQEEMWRQEEKIHEQEEIW 492

Query: 444 QDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEE 503
           + Q+EK+ E EEK++++EEK+  QEEKI+ QEEKI+EQEEK WRQE+ ++++E++W +EE
Sbjct: 493 R-QKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEE 551

Query: 504 KMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGK 563
           KM  ++EK+WE EEK QEQE+KM RQEEK+REQE ++W+QEEK++EQE + QE EE++ K
Sbjct: 552 KM-HEQEKIWE-EEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWK 609

Query: 564 LGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQQYVAAYQQL 623
             +K        RE   +       I + E K +E + + Q+Q+   G  ++ +   ++ 
Sbjct: 610 QEEKI-------REQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEK 662

Query: 624 ASGKEALPSCSSRKLR 639
              +E        K+R
Sbjct: 663 MQEQEETMWRQEEKIR 678



 Score =  389 bits (1000), Expect = e-108
 Identities = 242/539 (44%), Positives = 331/539 (61%), Gaps = 58/539 (10%)

Query: 66  LSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVK 125
           +++ E   +N K +   +  E +  E   + K+ K  L+R    LP  +   +A   H+ 
Sbjct: 214 ITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEA--DHLG 271

Query: 126 KNSDEVKSSFKKRQEK---MNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHF 182
           K    V +  + + E+    N  N    +++  ++  ++  E   Q++ E    +E    
Sbjct: 272 KELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIR 331

Query: 183 DHAVRMGTYIEKLTKERDAPSLELYRNTITDEELKEKNA---ELQEKLRLVESEKSEIQL 239
           +   +M    E + ++ +    +       +E+++ +     E +EK+R  E    E + 
Sbjct: 332 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 391

Query: 240 NVKDLKRKLERAQLLLPQQQLQVEADRLGKE--LQSVSAKLQAQVEENELWNLLNQQQEE 297
            +++L+ K+   + +  Q++ + E +++ ++   Q   AK+  Q E+        ++QE+
Sbjct: 392 KIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEK 451

Query: 298 KMWRQEEKIQEQE-----------EKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQED 346
           KMWRQEEKI EQE           E+M  QE KI EQEE +WRQ+EKMHEQEEKIR+QE+
Sbjct: 452 KMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEE-IWRQKEKMHEQEEKIRKQEE 510

Query: 347 KMWRQEEKIREQEEKIREQEEKMWRQEEKIRE---------------------------- 378
           K+WRQEEKIREQEEKIREQEEKMWRQEEKIRE                            
Sbjct: 511 KVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQED 570

Query: 379 ----QDEKIQEQEEEMWRQEEKIREQEEKRQ---EKMWRQEKKMREQDEKIREQEEEMWR 431
               Q+EKI+EQEE++WRQEEKIREQEEKRQ   EKMW+QE+K+REQ+EKI+EQEE++  
Sbjct: 571 KMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIRE 630

Query: 432 QEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQ-EK 490
           QEEKIRE EEM Q+QEEK+ E EEKM E+EEKMQEQEE + RQEEKI+EQE+K   Q EK
Sbjct: 631 QEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEK 690

Query: 491 LLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQE 549
           + +QEE + EQEEKMW QEEKM EQEEKMQEQEEKM+RQEEKM EQEVRL QQEEKMQE
Sbjct: 691 IREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749



 Score =  247 bits (631), Expect = 2e-65
 Identities = 163/435 (37%), Positives = 247/435 (56%), Gaps = 85/435 (19%)

Query: 38  KLEQQSKVRNKGHGKPREKSIADEKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSK 97
           K+ +Q K+R +   +  E+ I ++            E R+ +  K W +++ + E E+  
Sbjct: 399 KMHEQEKIREQEEKRQEEEKIREQ------------EKRQEQEAKMWRQEEKIREQEE-- 444

Query: 98  QCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKK 157
           + +E  K++      +E I +                    QEK+ E+     KR   ++
Sbjct: 445 KIREQEKKM---WRQEEKIHE--------------------QEKIREE----EKRQEQEE 477

Query: 158 PWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEELK 217
            W          R E  + E+   +    +M    EK+ K+ +    +++R      E +
Sbjct: 478 MW----------RQEEKIHEQEEIWRQKEKMHEQEEKIRKQEE----KVWRQEEKIREQE 523

Query: 218 EKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAK 277
           EK  E +EK+   E +  E                    Q+++  E +++  E + +  +
Sbjct: 524 EKIREQEEKMWRQEEKIRE--------------------QEEMWREEEKM-HEQEKIWEE 562

Query: 278 LQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQ 337
            + Q +E+++W     +QEEK+  QEEK+  QEEK+ EQE K +EQEEKMW+QEEK+ EQ
Sbjct: 563 EKRQEQEDKMW-----RQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQ 617

Query: 338 EEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKI 397
           EEKI+EQE+K+  QEEKIREQEE  +EQEEKM  QEEK+ EQ+EK+QEQEE MWRQEEKI
Sbjct: 618 EEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKI 677

Query: 398 REQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKM 457
           REQE+K +E    QE+K+REQ+E ++EQEE+MW QEEK+ E EE MQ+QEEK+R  EEKM
Sbjct: 678 REQEKKIRE----QEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKM 733

Query: 458 QEEEEKMQEQEEKIQ 472
            E+E ++++QEEK+Q
Sbjct: 734 WEQEVRLRQQEEKMQ 748


>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 828

 Score =  424 bits (1090), Expect = e-118
 Identities = 228/389 (58%), Positives = 303/389 (77%), Gaps = 43/389 (11%)

Query: 191 YIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLER 250
           YIE+LTKERDA SLELYRNTIT+EELK+KNAELQEKLRL ESEKSEIQLNVK+LKRKLER
Sbjct: 160 YIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLER 219

Query: 251 AQLLLPQQQ---LQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQ 307
           A+ LLPQ Q   LQ E  R  +EL+    K+              ++QEEKMWRQEE+++
Sbjct: 220 AKFLLPQVQTNTLQEEMWRQEEELREQEKKI--------------RKQEEKMWRQEERLR 265

Query: 308 EQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEE 367
           EQE KM       REQEEKM RQE+++ EQE+++REQE ++ R+++K+REQEE+++EQEE
Sbjct: 266 EQEGKM-------REQEEKMRRQEKRLREQEKELREQEKEL-REQKKLREQEEQMQEQEE 317

Query: 368 KMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEK---RQEKMWRQEKKMREQDEKIRE 424
           KMW QEEK+REQ+EK+  QEE +W QE+++REQE+K   ++E+MW Q++++RE++E++RE
Sbjct: 318 KMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMRE 377

Query: 425 QEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEK------I 478
           Q E+MW QEEK++E EE ++++E+K+RE EE M+E+EEKMQ+QEE +  QEEK      +
Sbjct: 378 Q-EKMWEQEEKMQE-EERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRL 435

Query: 479 QEQEEKTWRQEKLLKQEEKIWEQEEK------MWRQEEKMWEQEEKMQEQEEKMQRQEEK 532
            EQ+EK W QEK+ +QEEKIWEQEEK      MW QE+KMW Q EKM+EQE++M  QEEK
Sbjct: 436 PEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQ-EKMREQEDQMWEQEEK 494

Query: 533 MREQEVRLWQQEEKMQEQEVRLQELEERL 561
           MR+QE ++W QEE+M EQ+ RL+E EER+
Sbjct: 495 MRDQEQKMWDQEERMWEQDERLREKEERM 523



 Score =  348 bits (894), Expect = 7e-96
 Identities = 223/559 (39%), Positives = 346/559 (61%), Gaps = 54/559 (9%)

Query: 21  KSPVLSDEDSDLDFHINKLEQQSKVRNKGHGKPREKSIADEKFFQLSEMEAYLENRKRRG 80
           K  +   E S++  ++ +L+++ +       + +  ++ +E + Q  E+    +  +++ 
Sbjct: 195 KLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQE 254

Query: 81  TKRWDEDDDLEESEDS-KQCKESLKRVTFTLPDDEAI--EDAGVSHVKKNSDEVKSSFKK 137
            K W +++ L E E   ++ +E ++R    L + E    E       +K   E +   ++
Sbjct: 255 EKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQE 314

Query: 138 RQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTK 197
           ++EKM E+    R++   +K W          R E  L E+              E+  K
Sbjct: 315 QEEKMWEQEEKMREQE--EKMW----------RQEERLWEQEKQMR---------EQEQK 353

Query: 198 ERDAPSLELYRNTITDEELKEKNAELQEKLRLVESE-KSEIQLNVKDLKRKLERAQLLLP 256
            RD       R    DE L+EK   ++E+ ++ E E K + +  +++ ++K+   +  + 
Sbjct: 354 MRDQEE----RMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMR 409

Query: 257 QQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQ 316
           +Q+         +++Q     +  Q EE E       +Q+EK+W QE K+QEQEEK+ EQ
Sbjct: 410 EQE---------EKMQKQEENMWEQ-EEKEWQQQRLPEQKEKLWEQE-KMQEQEEKIWEQ 458

Query: 317 ELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKI 376
           E KIR+QEE MW QE+KM  QE K+REQED+MW QEEK+R+QE+K+ +QEE+MW Q+E++
Sbjct: 459 EEKIRDQEE-MWGQEKKMWRQE-KMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERL 516

Query: 377 REQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKI 436
           RE++E+++EQ ++MW+QEEK+RE E+K QE    QEKK  +Q+EK+RE EE M  +E+K+
Sbjct: 517 REKEERMREQ-KKMWQQEEKMRE-EKKTQE----QEKKTWDQEEKMRE-EERMREREKKM 569

Query: 437 RELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQE---KLLK 493
           RE EEMM++QEEK++E EEKM+E+EEKM EQEEK+Q QEEK+ EQEEK W QE   K+ +
Sbjct: 570 REEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQE 629

Query: 494 QEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVR 553
           QEE +WEQEEKM  QEEKMWEQEEKM+EQEEKM+ QEEKM+ QE ++ +QEEKMQ QE +
Sbjct: 630 QEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEK 689

Query: 554 LQELEERLGKLGQKAELLG 572
           ++E EE++   GQ+ ++ G
Sbjct: 690 MREQEEKM--RGQEEKMWG 706



 Score =  203 bits (517), Expect = 4e-52
 Identities = 125/383 (32%), Positives = 224/383 (58%), Gaps = 51/383 (13%)

Query: 272 QSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQE 331
           +++  +++AQ     +      + E  ++  ++  ++ E+    +   +  +    W   
Sbjct: 81  EALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGESKDLAGRLHHSWHFA 140

Query: 332 EKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQ----- 386
            ++      +     K  R  E++ ++ + +  +  +     E++++++ ++QE+     
Sbjct: 141 GELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAE 200

Query: 387 --------------------------------EEEMWRQEEKIREQEE---KRQEKMWRQ 411
                                           +EEMWRQEE++REQE+   K++EKMWRQ
Sbjct: 201 SEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQ 260

Query: 412 EKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKI 471
           E+++REQ+ K+REQEE+M RQE+++RE E+ +++QE++LRE ++K++E+EE+MQEQEEK+
Sbjct: 261 EERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELRE-QKKLREQEEQMQEQEEKM 319

Query: 472 QRQEEKIQEQEEKTWRQ-EKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQE------E 524
             QEEK++EQEEK WRQ E+L +QE+++ EQE+KM  QEE+MWEQ+E+++E+E      E
Sbjct: 320 WEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQE 379

Query: 525 KMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLP 584
           KM  QEEKM+E+E R+ ++E+KM+E+E  ++E EE++ K  Q+  +     +E   QRLP
Sbjct: 380 KMWEQEEKMQEEE-RIREREKKMREEEETMREQEEKMQK--QEENMWEQEEKEWQQQRLP 436

Query: 585 TLTPILQVELKSQEAQSLQQQQD 607
                L  + K QE +    +Q+
Sbjct: 437 EQKEKLWEQEKMQEQEEKIWEQE 459



 Score =  200 bits (508), Expect = 4e-51
 Identities = 140/433 (32%), Positives = 242/433 (55%), Gaps = 53/433 (12%)

Query: 38  KLEQQSKVRNKGHGKPREKSIADEKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSK 97
           +L +Q K   +   K R++   +E+ ++  E     E R R   K W++++ ++E E  +
Sbjct: 339 RLWEQEKQMREQEQKMRDQ---EERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIR 395

Query: 98  QCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEV---------------KSSFKKRQEKM 142
           + ++ ++    T+ + E        ++ +  ++                +   ++++EK+
Sbjct: 396 EREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKI 455

Query: 143 NEKNYTFRKRVVI----KKPW----LRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEK 194
            E+    R +  +    KK W    +R  E    ++ E    +E   +D   RM    E+
Sbjct: 456 WEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDER 515

Query: 195 LTKERDAPSLELYRNTITDEELKE-KNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQL 253
           L +E++    E  +    +E+++E K  + QEK    + EK   +  +++ ++K+   + 
Sbjct: 516 L-REKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEE 574

Query: 254 LLPQQQ--LQVEADRLGKELQSV-SAKLQAQVEENELWNLLNQQQEEKMWRQEE--KIQE 308
           ++ +Q+  +Q + +++ ++ + +   + + Q +E ++W     +QEEKMW QEE  K+QE
Sbjct: 575 MMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMW-----EQEEKMWEQEEEDKMQE 629

Query: 309 QEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEK 368
           QEE M EQE K++EQEEKMW QEEKM EQEEK+REQE+KM  QEEK+REQEEK++ QEEK
Sbjct: 630 QEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEK 689

Query: 369 MWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEE 428
           M  QEEK+R Q+EK+  QEE+MW QE           EKMW QE +MRE++E+IR+Q+E+
Sbjct: 690 MREQEEKMRGQEEKMWGQEEKMWGQE-----------EKMWGQE-EMREKEERIRDQKEK 737

Query: 429 MWRQEEKIRELEE 441
           M   +E++ E EE
Sbjct: 738 M---QERLPEHEE 747



 Score =  134 bits (337), Expect = 3e-31
 Identities = 95/339 (28%), Positives = 182/339 (53%), Gaps = 28/339 (8%)

Query: 294 QQEEKMWRQEEKIQEQEEKMCEQELKI-----REQEEKMWRQEEKMHEQEE-KIREQED- 346
           + E+K   Q ++   +E +  +  ++I      E E  ++  ++   + E+  + E +D 
Sbjct: 70  EDEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGESKDL 129

Query: 347 -----KMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQE 401
                  W    +++     +    +K  R  E++ ++ + +  +        E+++++ 
Sbjct: 130 AGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKN 189

Query: 402 EKRQEKMWRQEKKMREQDEKIREQEEEMWRQ-----EEKIRELEEMMQDQEEKLREVEEK 456
            + QEK+   E +  E    ++E + ++ R      + +   L+E M  QEE+LRE E+K
Sbjct: 190 AELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKK 249

Query: 457 MQEEEEKMQE-----QEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEK 511
           +     + QE     QEE+++ QE K++EQEEK  RQEK L+++EK   ++EK  R+++K
Sbjct: 250 I-----RKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKK 304

Query: 512 MWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELL 571
           + EQEE+MQEQEEKM  QEEKMREQE ++W+QEE++ EQE +++E E+++    ++    
Sbjct: 305 LREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQ 364

Query: 572 GGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYR 610
               RE   +R+     + + E K QE + +++++   R
Sbjct: 365 DERLREK-EERMREQEKMWEQEEKMQEEERIREREKKMR 402



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 51/279 (18%), Positives = 118/279 (42%), Gaps = 38/279 (13%)

Query: 395 EKIREQEEKRQEKMWRQEKKMRE---QDEKIR-------EQEEEMWRQEEKIRELEEMMQ 444
           E     E++++     QE   RE   QD  IR       E E  ++  ++  R+ E+   
Sbjct: 64  EGCHSPEDEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNL 123

Query: 445 DQEEKLR-------EVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEE--------KTWRQE 489
            + + L            ++Q     +    +K  R  E++ ++ +         T   E
Sbjct: 124 GESKDLAGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNE 183

Query: 490 KLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVR-----LWQQE 544
           +L K+  ++   +EK+   E +  E +  ++E + K++R +  + + +       +W+QE
Sbjct: 184 ELKKKNAEL---QEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQE 240

Query: 545 EKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQ 604
           E+++EQE ++++ EE++ +  ++     G  RE   +       + + E + +E +   +
Sbjct: 241 EELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELR 300

Query: 605 QQDHYRGHLQQYVAAYQQLASGKEALPSCSSRKLRAKRW 643
           +Q   R   +Q     +++   +E +     R+   K W
Sbjct: 301 EQKKLREQEEQMQEQEEKMWEQEEKM-----REQEEKMW 334


>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 899

 Score =  419 bits (1078), Expect = e-117
 Identities = 249/505 (49%), Positives = 333/505 (65%), Gaps = 106/505 (20%)

Query: 191 YIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLER 250
           YIE+LTKERDA SLELYRNTIT+EELK+KNAELQEKL L ESEKSEIQLNVK+LKRKLER
Sbjct: 198 YIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLER 257

Query: 251 AQLLLPQQQ---LQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQ 307
           A+ LLPQ Q   LQ E  R  +EL+    K++ Q  E ++W     +QEE++  QE K++
Sbjct: 258 AKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQ--EEKMW-----RQEERLREQEGKMR 310

Query: 308 EQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEE 367
           EQEEKM  QE ++REQE+++  QE+++ EQ+E +REQE++M  QEEK+ EQEEK+REQEE
Sbjct: 311 EQEEKMWRQEKRLREQEKELREQEKELREQKE-LREQEEQMQEQEEKMWEQEEKMREQEE 369

Query: 368 KMWRQEEKI-------REQDEKIQEQEEEMWRQEEKIREQEE--KRQEKMW------RQE 412
           KMWRQEE++       REQ++K+++QEE MW Q+E++RE+EE  + QEKMW      R+E
Sbjct: 370 KMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREE 429

Query: 413 KKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQE------------- 459
           KKM+EQ++K R+QEE+M ++EE+IRE E+ M+++EE +RE EEKMQ+             
Sbjct: 430 KKMQEQEKKTRDQEEKM-QEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEW 488

Query: 460 -------------EEEKMQEQEEKIQRQEEKIQEQEE------KTWRQEKLLKQEEKIWE 500
                        E+EKMQEQEEKI  QEEKI++QEE      K WRQEK+ +QE+++WE
Sbjct: 489 QQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWE 548

Query: 501 QEEKMWRQEEKMWEQEEKMQ--------------------------------------EQ 522
           QEEKM  QE+KMW+QEE+M+                                      EQ
Sbjct: 549 QEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQ 608

Query: 523 EEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQR 582
           EEKMQ QEEKM+EQE ++W+QEEKMQEQE ++ E EE++ +  +K             QR
Sbjct: 609 EEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKM---------WEQQR 659

Query: 583 LPTLTPILQVELKSQEAQSLQQQQD 607
           LP     L    K QE + +Q+Q++
Sbjct: 660 LPEQKEKLWEHEKMQEQEKMQEQEE 684



 Score =  345 bits (884), Expect = 1e-94
 Identities = 222/666 (33%), Positives = 380/666 (57%), Gaps = 87/666 (13%)

Query: 21  KSPVLSDEDSDLDFHINKLEQQSKVRNKGHGKPREKSIADEKFFQLSEMEAYLENRKRRG 80
           K P+   E S++  ++ +L+++ +       + +  ++ +E + Q  E+    +  +++ 
Sbjct: 233 KLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQE 292

Query: 81  TKRWDEDDDLEESEDS-KQCKESLKRVTFTLPDDEAI--EDAGVSHVKKNSDEVKSSFKK 137
            K W +++ L E E   ++ +E + R    L + E    E       +K   E +   ++
Sbjct: 293 EKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQE 352

Query: 138 RQEKMNEKNYTFRKRVVIKKPWL---RLGEVTAQKRPENS---------------LLEET 179
           ++EKM E+    R++   +K W    RL E   Q R +                 L E+ 
Sbjct: 353 QEEKMWEQEEKMREQE--EKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKE 410

Query: 180 LHFDHAVRMGTYIEKLTKER-----DAPSLELYRNTITDEELKEKNAELQEKLRLVESEK 234
                  +M   +EK+ +E+     +  + +       +E ++E+  +++E+   +  ++
Sbjct: 411 ERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQE 470

Query: 235 SEIQLNVKDL----------KRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEE 284
            ++Q   +++          +R  E+ + L  Q+++Q + +++ ++ + +  + +   +E
Sbjct: 471 EKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQE 530

Query: 285 NELWNLLN-QQQEEKMWRQEEKIQEQEEKMCEQE----LKIREQEEKMWRQEEKMHEQE- 338
            ++W     ++QE++MW QEEK+++QE+KM +QE     K +EQE+K W QEEKM E+E 
Sbjct: 531 KKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEER 590

Query: 339 -----EKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQ 393
                +K+RE+E+ M  QEEK++EQEEK++EQEEKMW QEEK++EQ+EK+ EQEE+MW Q
Sbjct: 591 MREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQ 650

Query: 394 EEKIREQEE--KRQEKMWRQEK-----KMREQDEKIREQE---------------EEMWR 431
           EEK+ EQ+   +++EK+W  EK     KM+EQ+EKI EQE               +E  R
Sbjct: 651 EEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMR 710

Query: 432 QEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKL 491
           +EE +RE E+ M+++EE +RE EEKMQE+EEKMQEQEE++  QEEK+ EQEEK W Q++L
Sbjct: 711 EEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRL 770

Query: 492 LKQEEKIWEQE-----EKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEK 546
            +Q+EK+WE E     EK+W QEEKM +QEEKM+ QEEKM+ QEEKMR QE ++W QEEK
Sbjct: 771 PEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEK 830

Query: 547 MQEQEVRLQELEERL-GKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQ 605
           M  QE ++   EE++ G+  +  E + G   +   Q         + +++ QE + +++Q
Sbjct: 831 MWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQ---------EEKMRGQE-EKMREQ 880

Query: 606 QDHYRG 611
           ++  RG
Sbjct: 881 EEKMRG 886



 Score =  332 bits (850), Expect = 9e-91
 Identities = 221/587 (37%), Positives = 337/587 (57%), Gaps = 111/587 (18%)

Query: 40  EQQSKVRNKGHGKPREKSIADEKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQC 99
           EQ+ K+R +     R++    E+  Q+ E E  + +++ R    W++D+ L E E+  + 
Sbjct: 359 EQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEER---MWEQDERLREKEERMRE 415

Query: 100 KESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSS-----FKKRQEKMNEKNYTFRKRVV 154
           +E +      + +++ +++      KK  D+ +        ++R++KM E+  T R++  
Sbjct: 416 QEKMWEQVEKMREEKKMQE----QEKKTRDQEEKMQEEERIREREKKMREEEETMREQ-- 469

Query: 155 IKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDAPSLELYRNTITDE 214
                    E   QK+ EN   +E              EK  +++  P            
Sbjct: 470 ---------EEKMQKQEENMWEQE--------------EKEWQQQRLP------------ 494

Query: 215 ELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSV 274
           E KEK  E QEK++  E +  E +  ++D +    + + +  Q++++ + D++ ++ + +
Sbjct: 495 EQKEKLWE-QEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKM 553

Query: 275 SAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKM 334
             + Q   ++ E      Q+QE+K W QEEK++E EE+M E+E K+RE+EE M  QEEKM
Sbjct: 554 RDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMRE-EERMREREKKMREEEEMMREQEEKM 612

Query: 335 HEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQD-------------- 380
            EQEEK++EQE+KMW QEEK++EQEEK+ EQEEKMW QEEK+ EQ               
Sbjct: 613 QEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEK 672

Query: 381 ----EKIQEQEEEMWRQE----------------EKIREQEEKRQ---------EKMWRQ 411
               EK+QEQEE++W QE                EK+RE+E  R+         E M  Q
Sbjct: 673 MQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQ 732

Query: 412 EKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQE------------EKLREVEEKMQE 459
           E+KM+EQ+EK++EQEEEMW QEEK+ E EE M +Q+            EK++E +EK+ E
Sbjct: 733 EEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQE-QEKIWE 791

Query: 460 EEEKMQEQEEKIQRQEEKIQEQEEK-TWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEK 518
           +EEKM++QEEK++ QEEK++ QEEK   ++EK+  QEEK+W QEEKMW QEEKMW QEEK
Sbjct: 792 QEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEK 851

Query: 519 MQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLG 565
           M   EEKMQ QEEKMREQE ++  QEEKM+EQE +++  EE++  +G
Sbjct: 852 M---EEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEKIYCVG 895



 Score =  204 bits (518), Expect = 3e-52
 Identities = 125/346 (36%), Positives = 203/346 (58%), Gaps = 69/346 (19%)

Query: 328 WRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQ- 386
           W    ++      +  +  K  R  E++ ++ + +  +  +     E++++++ ++QE+ 
Sbjct: 175 WHFAGELQRALSAVSTRHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKL 234

Query: 387 ------------------------------------EEEMWRQEEKIREQEE---KRQEK 407
                                               +EEMWRQEE++REQE+   K++EK
Sbjct: 235 PLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEK 294

Query: 408 MWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQE------EKLREVEEKMQEEE 461
           MWRQE+++REQ+ K+REQEE+MWRQE+++RE E+ +++QE      ++LRE EE+MQE+E
Sbjct: 295 MWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQE 354

Query: 462 EKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLK-QEEKIWEQEEKMW-------------R 507
           EKM EQEEK++ QEEK+  QEE+ W QEK ++ QE+K+ +QEE+MW             R
Sbjct: 355 EKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMR 414

Query: 508 QEEKMWEQ------EEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERL 561
           ++EKMWEQ      E+KMQEQE+K + QEEKM+E+E R+ ++E+KM+E+E  ++E EE++
Sbjct: 415 EQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEE-RIREREKKMREEEETMREQEEKM 473

Query: 562 GKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQD 607
            K  Q+  +     +E   QRLP     L  + K QE +    +Q+
Sbjct: 474 QK--QEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQE 517



 Score =  148 bits (373), Expect = 2e-35
 Identities = 135/484 (27%), Positives = 233/484 (48%), Gaps = 64/484 (13%)

Query: 134 SFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIE 193
           S K RQ K+ E     +K+    + W   G  T     +   +    + +     G +  
Sbjct: 14  SEKTRQNKLAEA----KKKFTDYRQWNIAGVGTGATDTKKKKINHGTNPETTTSGGCHSP 69

Query: 194 KLTKERDAPSLELYRNTITDEELKEKNAELQEK-LRLVESEKSEIQLNV---KDLKRKLE 249
           + T++  A   E  + +   +E   +  E Q+  +R++  +K+E++  +   +D  RK E
Sbjct: 70  EDTQQNRAQLKEEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFE 129

Query: 250 RAQLLLPQQ-QLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQE 308
              L  P    L +     G  L  VS  L    E  +L   L+       W    ++Q 
Sbjct: 130 DGNLGTPSSFNLALSQAFRGSPLGCVSTSL-IPGESKDLAGRLHHS-----WHFAGELQR 183

Query: 309 QEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEK 368
               +  +  K     E++ ++ + +  +          ++R      E ++K  E +EK
Sbjct: 184 ALSAVSTRHKKADRYIEELTKERDALSLE----------LYRNTITNEELKKKNAELQEK 233

Query: 369 MWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEE 428
           +   E +  E    IQ   +E+ R+ E+                 K      +    +EE
Sbjct: 234 LPLAESEKSE----IQLNVKELKRKLERA----------------KFLLPQVQTNTLQEE 273

Query: 429 MWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQ 488
           MWRQEE++RE E+ ++ QEEK+   EE+++E+E KM+EQEEK+ RQE++++EQE++   Q
Sbjct: 274 MWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQ 333

Query: 489 EKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQ 548
           EK L++++++ EQEE+M  QEEKMWEQEEKM+EQEEKM RQEE       RLW+QE++M 
Sbjct: 334 EKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEE-------RLWEQEKQM- 385

Query: 549 EQEVRLQE--LEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQ 606
               R QE  + ++  ++ ++ E L    RE   +R+     + +   K +E + +Q+Q+
Sbjct: 386 ----REQEQKMRDQEERMWEQDERL----REK-EERMREQEKMWEQVEKMREEKKMQEQE 436

Query: 607 DHYR 610
              R
Sbjct: 437 KKTR 440



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 36/201 (17%), Positives = 92/201 (45%), Gaps = 14/201 (6%)

Query: 449 KLREVEEKMQEEEEKMQEQEEKIQRQEEKIQ-EQEEKTWRQEKLLKQEEKIWEQEEKMWR 507
           +L+     +    +K     E++ ++ + +  E    T   E+L K+  ++   +EK+  
Sbjct: 180 ELQRALSAVSTRHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAEL---QEKLPL 236

Query: 508 QEEKMWEQEEKMQEQEEKMQRQEEKMREQEVR-----LWQQEEKMQEQEVRLQELEERLG 562
            E +  E +  ++E + K++R +  + + +       +W+QEE+++EQE ++++ EE++ 
Sbjct: 237 AESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMW 296

Query: 563 KLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQQYVAAYQQ 622
           +  ++     G  RE   +       + + E + +E +   ++Q   R   +Q     ++
Sbjct: 297 RQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEK 356

Query: 623 LASGKEALPSCSSRKLRAKRW 643
           +   +E +     R+   K W
Sbjct: 357 MWEQEEKM-----REQEEKMW 372


>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 436

 Score =  319 bits (818), Expect = 4e-87
 Identities = 178/419 (42%), Positives = 292/419 (69%), Gaps = 48/419 (11%)

Query: 211 ITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKE 270
           IT+EELKEKNAELQE+L+LVE+EKSEIQL++K+LKRKLE  ++ LPQ+    E +   +E
Sbjct: 4   ITNEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVRE 63

Query: 271 LQSVSAKLQAQVEENELWNLLNQ---------------------------------QQEE 297
            +    + + QV E E   +  Q                                 +QE 
Sbjct: 64  QEGQVREQEGQVREQE-GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 122

Query: 298 KMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIRE 357
           ++  QE +++EQE ++ EQE ++REQE ++  QE ++ EQE ++REQE ++  QE ++RE
Sbjct: 123 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 182

Query: 358 QEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEE---KRQEKMWRQEKK 414
           QE ++REQE +M  QE ++ EQ+E++ EQEE+M +QEE++ EQEE   K++E+M  QE++
Sbjct: 183 QEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQ 242

Query: 415 MREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKL------REVEEKMQEEEEKMQEQE 468
           +++Q+E++++QEE+M +QEE++RE EE M++QEE++       E EE+  E+EE+M+EQE
Sbjct: 243 VQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQE 302

Query: 469 EKIQRQEEKIQEQEEKTWRQEKLL-KQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQ 527
           E+++ QEE+++EQEE+   QE+ + KQEE++WEQ+E+MW Q+E+MW+QEE+M EQEE+MQ
Sbjct: 303 EQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQ 362

Query: 528 RQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLG----KLGQKAELLGGAGRESGSQR 582
           +QEE++R+QE ++ +QEE+M++QE ++++ EE++G    ++G++ E +     + G Q+
Sbjct: 363 KQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQK 421



 Score =  266 bits (681), Expect = 3e-71
 Identities = 152/398 (38%), Positives = 279/398 (70%), Gaps = 38/398 (9%)

Query: 215 ELKEKNAELQEK---LRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQV-EADRLGKE 270
           +++E+  +++E+   +R  E +  E +  V++ + ++   +  + +Q+ QV E +   +E
Sbjct: 67  QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 126

Query: 271 LQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQ 330
            +    + + QV E E      ++QE ++  QE +++EQE ++ EQE ++REQE ++  Q
Sbjct: 127 QEGQVREQEGQVREQEGQV---REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 183

Query: 331 EEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEM 390
           E ++ EQE ++ EQE +M  QEE++ EQEE++++QEE+M  QEE++R+Q+E++ EQEE++
Sbjct: 184 EGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQV 243

Query: 391 WRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKL 450
            +QEE++++QE    E+M +QE++MREQ+E++REQEE+M +Q+E+  E EE   +QEE++
Sbjct: 244 QKQEEQVQKQE----EQMRKQEEQMREQEEQMREQEEQMLKQKEQ-TEQEEQTGEQEEQM 298

Query: 451 REVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEE 510
           RE EE+M+E+EE+M+EQEE+++ QEE++ +QEE+ W      +Q+E++WEQ+E+MW+QEE
Sbjct: 299 REQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMW------EQKEQMWEQKEQMWKQEE 352

Query: 511 KMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAEL 570
           +M EQEE+MQ+QEE++++QEE+MR+QE ++ +QEE+M++QE ++ E +E++G+  QK ++
Sbjct: 353 QMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGE--QKEQM 410

Query: 571 LGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDH 608
                RE             Q E   ++ + +++Q++H
Sbjct: 411 -----RE-------------QEEQMGEQKEQMRKQEEH 430



 Score =  257 bits (657), Expect = 2e-68
 Identities = 143/352 (40%), Positives = 259/352 (73%), Gaps = 10/352 (2%)

Query: 215 ELKEKNAELQEK---LRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQV-EADRLGKE 270
           +++E+  +++E+   +R  E +  E +  V++ + ++   +  + +Q+ QV E +   +E
Sbjct: 88  QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 147

Query: 271 LQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQ 330
            +    + + QV E E      ++QE ++  QE +++EQE ++ EQE ++ EQE +M  Q
Sbjct: 148 QEGQVREQEGQVREQEGQV---REQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQ 204

Query: 331 EEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEM 390
           EE+M EQEE++++QE++M  QEE++R+QEE++ EQEE++ +QEE++++Q+E++++QEE+M
Sbjct: 205 EEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQM 264

Query: 391 WRQEEKIREQEEK--RQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEE 448
             QEE++REQEE+  +Q++   QE++  EQ+E++REQEE+M  QEE++RE EE M++QEE
Sbjct: 265 REQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEE 324

Query: 449 KLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQ-EKLLKQEEKIWEQEEKMWR 507
           ++ + EE+M E++E+M EQ+E++ +QEE++ EQEE+  +Q E++ KQEE++ +QEE+M +
Sbjct: 325 QMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRK 384

Query: 508 QEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEE 559
           QEE+M +QEE+M EQ+E+M  Q+E+MREQE ++ +Q+E+M++QE  + E +E
Sbjct: 385 QEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436



 Score =  201 bits (512), Expect = 1e-51
 Identities = 117/341 (34%), Positives = 215/341 (63%), Gaps = 18/341 (5%)

Query: 290 LLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMW 349
           + N++ +EK    +E++Q  E +  E +L I+E + K+   +  +  QE ++REQE ++ 
Sbjct: 4   ITNEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPL-PQEGQVREQEGQVR 62

Query: 350 RQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMW 409
            QE ++REQE ++REQE ++  QE ++REQ+ +++EQE ++  QE ++REQE + +E   
Sbjct: 63  EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE--- 119

Query: 410 RQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEE 469
            QE ++REQ+ ++REQE ++  QE ++RE E  +++QE ++RE E +++E+E +++EQE 
Sbjct: 120 -QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 178

Query: 470 KIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQ 529
           +++ QE +++EQE +             + EQE +M  QEE+M EQEE+MQ+QEE+M  Q
Sbjct: 179 QVREQEGQVREQEGQ-------------MGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQ 225

Query: 530 EEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPI 589
           EE+MR+QE ++ +QEE++Q+QE ++Q+ EE++ K  ++        RE   Q L      
Sbjct: 226 EEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQT 285

Query: 590 LQVELKSQEAQSLQQQQDHYRGHLQQYVAAYQQLASGKEAL 630
            Q E   ++ + +++Q++  R   +Q     +Q+   +E +
Sbjct: 286 EQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQM 326



 Score =  172 bits (437), Expect = 7e-43
 Identities = 92/236 (38%), Positives = 163/236 (69%), Gaps = 4/236 (1%)

Query: 213 DEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQ 272
           +E++ E+  ++Q++   +  ++ +++   + +  + E+ Q    Q Q Q E  R  +E  
Sbjct: 205 EEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQM 264

Query: 273 SVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEE 332
               +   + EE  L      +QEE+   QEE+++EQEE+M EQE ++REQEE+M  QEE
Sbjct: 265 REQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEE 324

Query: 333 KMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWR 392
           +M +QEE++ EQ+++MW Q+E++ +QEE++ EQEE+M +QEE++R+Q+E++++QEE+M +
Sbjct: 325 QMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRK 384

Query: 393 QEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEE 448
           QEE++R+QE    E+M  Q+++M EQ E++REQEE+M  Q+E++R+ EE M +Q+E
Sbjct: 385 QEEQMRKQE----EQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436



 Score =  160 bits (405), Expect = 3e-39
 Identities = 108/421 (25%), Positives = 242/421 (57%), Gaps = 23/421 (5%)

Query: 24  VLSDEDSDLDFHINKLEQQ---SKVRNKGHGKPREKS-IADEKFFQLSEMEAYLEN---- 75
           ++  E S++  HI +L+++    K+     G+ RE+     E+  Q+ E E  +      
Sbjct: 22  LVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 81

Query: 76  -RKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSS 134
            R++ G  R  E    E+    ++ +  ++     + + E         V++   +V+  
Sbjct: 82  VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 141

Query: 135 ---FKKRQEKMNEKNYTFRKRV-VIKKPWLRLGEVTAQKRPENSLL--EETLHFDHAVRM 188
               ++++ ++ E+    R++   +++   ++ E   Q R +   +  +E    +   +M
Sbjct: 142 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQM 201

Query: 189 GTYIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKL 248
           G   E++ ++ +    +  +    +E+++++  ++ E+   V+ ++ ++Q   + ++++ 
Sbjct: 202 GEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQE 261

Query: 249 ERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQ--QQEEKMWRQEEKI 306
           E  Q+   ++Q++ + +++ K+ +    + Q   +E ++     Q  +QEE+M  QEE++
Sbjct: 262 E--QMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQM 319

Query: 307 QEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQE 366
           +EQEE+M +QE ++ EQ+E+MW Q+E+M +QEE++ EQE++M +QEE++R+QEE++R+QE
Sbjct: 320 REQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQE 379

Query: 367 EKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQE 426
           E+M +QEE++R+Q+E++ EQ+E+M  Q+E++REQE    E+M  Q+++MR+Q+E + EQ+
Sbjct: 380 EQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQE----EQMGEQKEQMRKQEEHMGEQK 435

Query: 427 E 427
           E
Sbjct: 436 E 436



 Score =  114 bits (286), Expect = 2e-25
 Identities = 78/275 (28%), Positives = 165/275 (60%), Gaps = 18/275 (6%)

Query: 377 REQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIR-EQEEEMWRQEEK 435
           R  +E+++E+  E+  QEE    + EK + ++  +E K + + +KI   QE ++  QE +
Sbjct: 3   RITNEELKEKNAEL--QEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQ 60

Query: 436 IRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQE-KLLKQ 494
           +RE E  +++QE ++RE E +++E+E +++EQE +++ QE +++EQE +   QE ++ +Q
Sbjct: 61  VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 120

Query: 495 EEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRL 554
           E ++ EQE ++  QE ++ EQE +++EQE +++ QE ++REQE ++ +QE +++EQE ++
Sbjct: 121 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 180

Query: 555 QELE----ERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYR 610
           +E E    E+ G++G++   +G    + G Q         + +++ QE Q + +Q++  R
Sbjct: 181 REQEGQVREQEGQMGEQEGQMGEQEEQMGEQ---------EEQMQKQEEQ-MGEQEEQMR 230

Query: 611 GHLQQYVAAYQQLASGKEALPSCSSRKLRAKRWLR 645
              +Q     +Q+   +E +     +  + +  +R
Sbjct: 231 KQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMR 265


>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 523

 Score =  229 bits (583), Expect = 8e-60
 Identities = 140/379 (36%), Positives = 231/379 (60%), Gaps = 56/379 (14%)

Query: 231 ESEKSEIQLNVKDLKRKL-----ERAQLLLPQ--------QQLQVEADRLGKELQSVSAK 277
           E +K EI L V+ L R L     + A+ L P+        +QLQ E + L KEL+SV  +
Sbjct: 121 EEKKHEIHL-VQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQ 179

Query: 278 LQAQVEENELWNLLNQ-------QQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQ 330
           LQA+VE N++ +LLN+       +QEE++  QEE+++EQEE++CEQE ++REQEE++  Q
Sbjct: 180 LQAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQEERLCEQEERLREQEERLREQ 239

Query: 331 EEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEM 390
           EE++ EQEE++RE E+++  QEE++ EQEE++REQEE++  QEE++ EQ+E+++EQEE +
Sbjct: 240 EERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQEERL 299

Query: 391 WRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKL 450
             QEE++REQEE           ++ EQ+E++REQEE +  QE+        +  QE  L
Sbjct: 300 CEQEERLREQEE-----------RLCEQEERLREQEERLCEQEK--------LPGQERLL 340

Query: 451 REVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEE 510
            EV EK+ E+E + +EQE  ++R  E++ E+ E+   QE+L +Q+E++W+QE        
Sbjct: 341 EEV-EKLLEQERRQEEQERLLER--ERLLEEVEELLEQERLRQQDERLWQQE-------- 389

Query: 511 KMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAEL 570
              ++ E+++E E  ++   E + EQ        E++  +     +LE+++ +L +    
Sbjct: 390 -TLQELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELKKS--- 445

Query: 571 LGGAGRESGSQRLPTLTPI 589
            GGA    GS+      P+
Sbjct: 446 -GGAEEPRGSESAAAARPV 463



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 67/310 (21%), Positives = 145/310 (46%), Gaps = 38/310 (12%)

Query: 68  EMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKN 127
           +++A +EN +        +++ L E E+  + +E   R           ++  +   ++ 
Sbjct: 179 QLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLRE----------QEERLCEQEER 228

Query: 128 SDEVKSSFKKRQEKMNEKNYTFRKRVV-IKKPWLRLGEVTAQKRPENSLLEETLHFDHAV 186
             E +   ++++E++ E+    R+    + +   RL E   + R +    EE LH +   
Sbjct: 229 LREQEERLREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQ----EERLH-EQEE 283

Query: 187 RMGTYIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKL-RLVESEKSEIQLNVKDLK 245
           R+    E+L ++ +    +  R    +E L E+   L+E+  RL E EK   Q      +
Sbjct: 284 RLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEKLPGQ------E 337

Query: 246 RKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEK 305
           R LE  + LL Q++ Q E +RL  E + +  +++  +E+  L     +QQ+E++W Q+E 
Sbjct: 338 RLLEEVEKLLEQERRQEEQERL-LERERLLEEVEELLEQERL-----RQQDERLW-QQET 390

Query: 306 IQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQ 365
           +QE E        ++RE E  +    E ++EQ  + R   +++  + +   + E++++E 
Sbjct: 391 LQELE--------RLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKEL 442

Query: 366 EEKMWRQEEK 375
           ++    +E +
Sbjct: 443 KKSGGAEEPR 452


>gi|239752551 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 238

 Score =  222 bits (566), Expect = 7e-58
 Identities = 112/177 (63%), Positives = 149/177 (84%), Gaps = 5/177 (2%)

Query: 309 QEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEK 368
           +EE+M E+E K+RE+EE M  QEEKM EQEEK+REQE+KMW QEEK++EQEEK+ EQEEK
Sbjct: 3   EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 62

Query: 369 MWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEK-RQEKMWRQEKKMREQDEKIREQEE 427
           MW QEEK+ EQ +++ EQ+E+MW Q+E++RE+EE+ R++KMW+Q +KMR   EK + QEE
Sbjct: 63  MWEQEEKMWEQ-QRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMR---EKKKTQEE 118

Query: 428 EMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEK 484
           +M  QEEK++E EEMM +QEEK++E EEKM E+EEKM+EQEEK++ QEEK+Q QEEK
Sbjct: 119 KMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEK 175



 Score =  219 bits (557), Expect = 8e-57
 Identities = 114/197 (57%), Positives = 153/197 (77%), Gaps = 20/197 (10%)

Query: 329 RQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEE 388
           R+EE+M E+E+K+RE+E+ M  QEEK++EQEEK+REQEEKMW QEEK++EQ+EK+ EQEE
Sbjct: 2   REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61

Query: 389 EMWRQEEKIREQEE--KRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQ 446
           +MW QEEK+ EQ+   +++EKMW Q++++RE++E++REQ  +MW+Q EK+R         
Sbjct: 62  KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQ--KMWQQVEKMR--------- 110

Query: 447 EEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMW 506
            EK +  EEKMQE+EEKMQEQEE +  QEEK+QEQEEK W      +QEEK+ EQEEKM 
Sbjct: 111 -EKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMW------EQEEKMREQEEKMR 163

Query: 507 RQEEKMWEQEEKMQEQE 523
            QEEKM  QEEKM++ E
Sbjct: 164 EQEEKMQGQEEKMRDVE 180



 Score =  215 bits (548), Expect = 9e-56
 Identities = 108/183 (59%), Positives = 150/183 (81%), Gaps = 10/183 (5%)

Query: 293 QQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQE 352
           +++E+KM  +EE ++EQEEKM EQE K+REQEEKMW QEEKM EQEEK+ EQE+KMW QE
Sbjct: 8   REREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE 67

Query: 353 EKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQE 412
           EK+ EQ +++ EQ+EKMW Q+E++RE++E+++EQ  +MW+Q EK+RE+++        QE
Sbjct: 68  EKMWEQ-QRLPEQKEKMWEQDERLREKEERMREQ--KMWQQVEKMREKKK-------TQE 117

Query: 413 KKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQ 472
           +KM+EQ+EK++EQEE MW QEEK++E EE M +QEEK+RE EEKM+E+EEKMQ QEEK++
Sbjct: 118 EKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMR 177

Query: 473 RQE 475
             E
Sbjct: 178 DVE 180



 Score =  209 bits (532), Expect = 6e-54
 Identities = 117/217 (53%), Positives = 157/217 (72%), Gaps = 27/217 (12%)

Query: 350 RQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMW 409
           R+EE++RE+E+K+RE+EE M  QEEK++EQ+EK++EQEE+MW QEEK++EQ    +EKMW
Sbjct: 2   REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQ----EEKMW 57

Query: 410 RQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEE-----EKM 464
                  EQ+EK+ EQEE+MW Q+ ++ E +E M +Q+E+LRE EE+M+E++     EKM
Sbjct: 58  -------EQEEKMWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQKMWQQVEKM 109

Query: 465 QE----QEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQ 520
           +E    QEEK+Q QEEK+QEQEE  W      +QEEK+ EQEEKMW QEEKM EQEEKM+
Sbjct: 110 REKKKTQEEKMQEQEEKMQEQEEMMW------EQEEKMQEQEEKMWEQEEKMREQEEKMR 163

Query: 521 EQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQEL 557
           EQEEKMQ QEEKMR+ E    +  E   +     QE+
Sbjct: 164 EQEEKMQGQEEKMRDVEPAGGEAGEGSPQDNPTAQEI 200



 Score =  198 bits (504), Expect = 1e-50
 Identities = 115/235 (48%), Positives = 159/235 (67%), Gaps = 30/235 (12%)

Query: 371 RQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMW 430
           R+EE++RE+++K++E+EE M  QEEK++EQEEK           MREQ+EK+ EQEE+M 
Sbjct: 2   REEERMREREKKMREEEEMMREQEEKMQEQEEK-----------MREQEEKMWEQEEKMQ 50

Query: 431 RQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQ-- 488
            QEEK+ E EE M +QEEK+ E ++++ E++EKM EQ+E+++ +EE+++EQ  K W+Q  
Sbjct: 51  EQEEKMWEQEEKMWEQEEKMWE-QQRLPEQKEKMWEQDERLREKEERMREQ--KMWQQVE 107

Query: 489 ---EKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEE 545
              EK   QEEK+ EQEEKM  QEE MWEQEEKMQEQEEKM  QEEKMREQE ++ +QEE
Sbjct: 108 KMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEE 167

Query: 546 KMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQ 600
           KMQ QE +++++E             GG   E   Q  PT   I+Q+    + AQ
Sbjct: 168 KMQGQEEKMRDVEP-----------AGGEAGEGSPQDNPTAQEIMQLFCGMKNAQ 211



 Score =  191 bits (486), Expect = 1e-48
 Identities = 103/175 (58%), Positives = 133/175 (76%), Gaps = 27/175 (15%)

Query: 283 EENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEK-- 340
           EE E+     ++QEEKM  QEEK++EQEEKM EQE K++EQEEKMW QEEKM EQEEK  
Sbjct: 16  EEEEMM----REQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMW 71

Query: 341 ----IREQEDKMWRQEEKIREQEEKIREQEEKMWRQ-----------EEKIREQDEKIQE 385
               + EQ++KMW Q+E++RE+EE++REQ  KMW+Q           EEK++EQ+EK+QE
Sbjct: 72  EQQRLPEQKEKMWEQDERLREKEERMREQ--KMWQQVEKMREKKKTQEEKMQEQEEKMQE 129

Query: 386 QEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELE 440
           QEE MW QEEK++EQEEK    MW QE+KMREQ+EK+REQEE+M  QEEK+R++E
Sbjct: 130 QEEMMWEQEEKMQEQEEK----MWEQEEKMREQEEKMREQEEKMQGQEEKMRDVE 180



 Score =  169 bits (428), Expect = 7e-42
 Identities = 94/192 (48%), Positives = 139/192 (72%), Gaps = 18/192 (9%)

Query: 241 VKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLN--QQQEEK 298
           +++ +R  ER + +  ++++  E +   +++Q    K++ Q  E ++W      Q+QEEK
Sbjct: 1   MREEERMREREKKMREEEEMMREQE---EKMQEQEEKMREQ--EEKMWEQEEKMQEQEEK 55

Query: 299 MWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIRE- 357
           MW QEEK+ EQEEKM EQ+ ++ EQ+EKMW Q+E++ E+EE++REQ  KMW+Q EK+RE 
Sbjct: 56  MWEQEEKMWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQ--KMWQQVEKMREK 112

Query: 358 ---QEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKK 414
              QEEK++EQEEKM  QEE + EQ+EK+QEQEE+MW QEEK+REQEEK +E    QE+K
Sbjct: 113 KKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMRE----QEEK 168

Query: 415 MREQDEKIREQE 426
           M+ Q+EK+R+ E
Sbjct: 169 MQGQEEKMRDVE 180



 Score =  145 bits (365), Expect = 1e-34
 Identities = 80/184 (43%), Positives = 125/184 (67%), Gaps = 21/184 (11%)

Query: 234 KSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSV-SAKLQAQVEENELWNLLN 292
           + E ++  ++ K + E   +   ++++Q + +++ ++ + +   + + Q +E ++W    
Sbjct: 2   REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMW---- 57

Query: 293 QQQEEKMWRQEEK------IQEQEEKMCEQELKIREQEE-----KMWRQEEKMHE----Q 337
            +QEEKMW QEEK      + EQ+EKM EQ+ ++RE+EE     KMW+Q EKM E    Q
Sbjct: 58  -EQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQ 116

Query: 338 EEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKI 397
           EEK++EQE+KM  QEE + EQEEK++EQEEKMW QEEK+REQ+EK++EQEE+M  QEEK+
Sbjct: 117 EEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKM 176

Query: 398 REQE 401
           R+ E
Sbjct: 177 RDVE 180



 Score =  111 bits (278), Expect = 2e-24
 Identities = 68/144 (47%), Positives = 94/144 (65%), Gaps = 23/144 (15%)

Query: 473 RQEEKIQEQEEKTWRQEKLLK-QEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEE 531
           R+EE+++E+E+K   +E++++ QEEK+ EQEEKM  QEEKMWEQEEKMQEQEEKM  QEE
Sbjct: 2   REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61

Query: 532 KMREQEVRLWQQE------EKMQEQEVRLQELEERL--GKLGQKAELLGGAGRESGSQRL 583
           KM EQE ++W+Q+      EKM EQ+ RL+E EER+   K+ Q+ E +    RE    + 
Sbjct: 62  KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKM----REKKKTQ- 116

Query: 584 PTLTPILQVELKSQEAQSLQQQQD 607
                    E K QE +   Q+Q+
Sbjct: 117 ---------EEKMQEQEEKMQEQE 131



 Score =  100 bits (250), Expect = 3e-21
 Identities = 57/129 (44%), Positives = 83/129 (64%), Gaps = 4/129 (3%)

Query: 478 IQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQE 537
           ++E+E    R++K+ ++EE + EQEEKM  QEEKM EQEEKM EQEEKMQ QEEKM EQE
Sbjct: 1   MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60

Query: 538 VRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQ 597
            ++W+QEEKM EQ    Q L E+  K+ ++ E L         Q++      ++ + K+Q
Sbjct: 61  EKMWEQEEKMWEQ----QRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQ 116

Query: 598 EAQSLQQQQ 606
           E +  +Q++
Sbjct: 117 EEKMQEQEE 125



 Score = 95.5 bits (236), Expect = 1e-19
 Identities = 61/182 (33%), Positives = 102/182 (56%), Gaps = 5/182 (2%)

Query: 164 EVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEELKEKNAEL 223
           E   ++R +    EE +  +   +M    EK+ ++ +    +++      +E +EK  E 
Sbjct: 4   EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEE----KMWEQEEKMQEQEEKMWEQ 59

Query: 224 QEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVE 283
           +EK+   + EK   Q  + + K K+      L +++ ++   ++ ++++ +  K + Q E
Sbjct: 60  EEKM-WEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEE 118

Query: 284 ENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIRE 343
           + +      Q+QEE MW QEEK+QEQEEKM EQE K+REQEEKM  QEEKM  QEEK+R+
Sbjct: 119 KMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRD 178

Query: 344 QE 345
            E
Sbjct: 179 VE 180


>gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo
           sapiens]
          Length = 479

 Score =  183 bits (464), Expect = 5e-46
 Identities = 116/296 (39%), Positives = 191/296 (64%), Gaps = 33/296 (11%)

Query: 231 ESEKSEIQLNVKDLKRKL-----ERAQLLLPQ--------QQLQVEADRLGKELQSVSAK 277
           E +K EI L V+ L R L     + A+ L P+        +QLQ E + L KEL+SV  +
Sbjct: 121 EEKKHEIHL-VQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQ 179

Query: 278 LQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQ 337
           LQA+VE N++ +LLN++QEE++  QEE++ EQEE++ EQE ++ EQEE++  QEE++ EQ
Sbjct: 180 LQAEVENNQMLSLLNRRQEERLREQEERLHEQEERLHEQEERLCEQEERLCEQEERLREQ 239

Query: 338 EEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQE-----EKIREQDEKIQEQEEEMWR 392
           EE++REQE+++  QEE++ EQEE++ EQEE++  QE     E++ E+ EK+ EQE    R
Sbjct: 240 EERLREQEERLHEQEERLCEQEERLCEQEERLCEQEKLPGQERLLEEVEKLLEQER---R 296

Query: 393 QEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQE-----EKIRELEEMMQDQE 447
           QEE+ R  E   +E++  + +++ EQ E++R+Q+E +W+QE     E++RELE +   + 
Sbjct: 297 QEEQERLLE---RERLLDEVEELLEQ-ERLRQQDERLWQQETLRELERLRELERLR--EL 350

Query: 448 EKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEE 503
           E+LRE+E  ++   E + EQ  + +   E++  + + T + E+ +K+ EK    EE
Sbjct: 351 ERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELEKSGGAEE 406



 Score =  143 bits (361), Expect = 4e-34
 Identities = 97/271 (35%), Positives = 162/271 (59%), Gaps = 26/271 (9%)

Query: 330 QEEKMHEQEEKIREQEDKMWRQEEKIREQE-EKIREQEEKMWRQEEKIREQDEKIQEQEE 388
           +EEK HE          K+ R   K++ Q  E +  +      + E+++++   ++++ E
Sbjct: 120 KEEKKHEIH-----LVQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELE 174

Query: 389 EMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEE 448
            + RQ +   E  +       RQE+++REQ+E++ EQEE +  QEE++ E EE + +QEE
Sbjct: 175 SVGRQLQAEVENNQMLSLLNRRQEERLREQEERLHEQEERLHEQEERLCEQEERLCEQEE 234

Query: 449 KLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQE------EKIWEQE 502
           +LRE EE+++E+EE++ EQEE++  QEE++ EQEE+   QEKL  QE      EK+ EQE
Sbjct: 235 RLREQEERLREQEERLHEQEERLCEQEERLCEQEERLCEQEKLPGQERLLEEVEKLLEQE 294

Query: 503 EKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQE-----EKMQEQEVRLQEL 557
            +   ++E++ E+E  + E EE ++  +E++R+Q+ RLWQQE     E+++E E RL+EL
Sbjct: 295 RRQ-EEQERLLERERLLDEVEELLE--QERLRQQDERLWQQETLRELERLRELE-RLREL 350

Query: 558 E-----ERLGKLGQKAELLGGAGRESGSQRL 583
           E     ER+ +LG +A     A   SG + L
Sbjct: 351 ERLRELERMLELGWEALYEQRAEPRSGFEEL 381



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 46/189 (24%), Positives = 102/189 (53%), Gaps = 11/189 (5%)

Query: 215 ELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKL-ERAQLLLPQQQLQVEADRL-GKE-- 270
           E +E+  E +E+LR  E    E +  + + + +L E+ + L  Q++   E ++L G+E  
Sbjct: 224 EQEERLCEQEERLREQEERLREQEERLHEQEERLCEQEERLCEQEERLCEQEKLPGQERL 283

Query: 271 LQSVSAKLQAQVEENELWNLLNQQQ---EEKMWRQEEKIQEQEEKMCEQELKIREQEEKM 327
           L+ V   L+ +  + E   LL +++   E +   ++E++++Q+E++ +QE  +RE E   
Sbjct: 284 LEEVEKLLEQERRQEEQERLLERERLLDEVEELLEQERLRQQDERLWQQE-TLRELER-- 340

Query: 328 WRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQE 387
            R+ E++ E  E++RE E  +    E + EQ  + R   E++  + +   + +++++E E
Sbjct: 341 LRELERLREL-ERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELE 399

Query: 388 EEMWRQEEK 396
           +    +E +
Sbjct: 400 KSGGAEEPR 408


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score =  180 bits (457), Expect = 3e-45
 Identities = 142/557 (25%), Positives = 298/557 (53%), Gaps = 58/557 (10%)

Query: 40   EQQSKVRNKGHGKPREKSIADEKFFQL-SEMEA-----YLENRKRRGTKRWDEDDDLEES 93
            EQ+     +   + R KS   +  +QL SE +A     Y   RK+ G +R  E ++    
Sbjct: 682  EQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRR 741

Query: 94   EDSKQCKESLKRVTFTLPDDEAIED---AGVSHVKKNSDEVKSSFKKRQEKMNEKNYTFR 150
             +S+   +  +R      ++E   D      +  K      + S +    +  E+     
Sbjct: 742  RESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAE 801

Query: 151  KRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDAPSLELYRNT 210
            +R   ++ +L   E   Q+R +    E+ L F          E+L +   A  L+   + 
Sbjct: 802  ERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEE------EQLQRRERAQQLQEEEDG 855

Query: 211  ITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKE 270
            + +++ + ++ E +        +K   QL     + +  R   L  +  LQ +  +  + 
Sbjct: 856  LQEDQERRRSQEQRR------DQKWRWQLE----EERKRRRHTLYAKPALQEQLRKEQQL 905

Query: 271  LQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMC--EQELKIREQEEKMW 328
            LQ    +LQ +  E        +Q++E+ +R+EE++Q++EE++   E+E + R++ E+ +
Sbjct: 906  LQEEEEELQREEREKR-----RRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQY 960

Query: 329  RQEEKMHEQEEKIREQEDKMWRQEE---KIREQEEKIREQEEKMWRQEEKIREQDEKIQE 385
            R+++K+ ++EE++  +E +  R++E   K RE+EE  +E+E+ +  + EK R Q+ + Q 
Sbjct: 961  RKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQY 1020

Query: 386  QEEEMWRQEEK--IREQEEKR----QEKMWRQEKKMREQDEKIREQEEEMWRQEE---KI 436
            ++++  +QEE+  +RE+ EKR    +E+ +R+E+++++++E++  +E E  R++E   + 
Sbjct: 1021 RKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQY 1080

Query: 437  RELEEMMQDQEEKLREVEEK--MQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQ--EKLL 492
            R+ EE+ Q++E+ LRE  EK   QE E + +E+EE  Q +E+ ++E+ EK  RQ  E+  
Sbjct: 1081 RKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQY 1140

Query: 493  KQEEKIWEQEEKMWRQE---------EKMWEQEEKMQEQEEKMQRQE-EKMREQEVRLWQ 542
            ++EE++ ++EE++ R+E         E+ + +EE++Q++EE++ R+E EK R++  R ++
Sbjct: 1141 REEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYR 1200

Query: 543  QEEKMQEQEVRLQELEE 559
            +EE++Q Q+ + +  +E
Sbjct: 1201 EEEELQRQKRKQRYRDE 1217



 Score =  177 bits (450), Expect = 2e-44
 Identities = 161/579 (27%), Positives = 297/579 (51%), Gaps = 82/579 (14%)

Query: 60  DEKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDE---AI 116
           D++ F+  + +   E  +RR  KR +++ +L E E+  + +E L++      D+E     
Sbjct: 118 DQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQR 177

Query: 117 EDAGVSHVKKNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLL 176
           ++      ++  +E   S K  + +        R+R +++       E   Q+R      
Sbjct: 178 QEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQ--- 234

Query: 177 EETLHFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSE 236
                           +++ +E +          +  EE K +  E Q +  L E E+  
Sbjct: 235 ----------------DRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQ- 277

Query: 237 IQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQE 296
                    RKLER +L   +Q+ + +  RL +E Q     L+ + EE        +QQE
Sbjct: 278 --------LRKLERQELRRERQEEEQQQQRLRREQQ-----LRRKQEEER-----REQQE 319

Query: 297 EKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQ----EDKMWRQE 352
           E+  R++++ +EQ+E+  EQ+L+ REQEE+  R+++   EQEE+ REQ    E +  R+E
Sbjct: 320 ER--REQQERREQQEERREQQLR-REQEER--REQQLRREQEEERREQQLRREQEEERRE 374

Query: 353 EKIREQEEKIREQE---EKMWRQEEKIREQDEKIQEQ----EEEMWRQEEKIREQEEKRQ 405
           +++R +++  REQ+   E+  R+E+++R + +  +EQ    E+++ R+++  REQEE+R 
Sbjct: 375 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERH 434

Query: 406 EKMWRQEKK----MREQDEK----IREQEEEMWRQEEKIRELEEMMQDQEE-------KL 450
           E+   QE++     REQ+E+     RE+E E   QE   R  +++ +DQEE       KL
Sbjct: 435 EQKHEQERREQRLKREQEERRDWLKREEETERHEQE---RRKQQLKRDQEEERRERWLKL 491

Query: 451 REVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEE 510
            E E + Q+E  + Q + E+ +R+E++++ QEE+   Q++L  +++   EQEE   R+E+
Sbjct: 492 EEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEE---RREQ 548

Query: 511 KMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAEL 570
            +  +EEK  EQE + QR + +  E+  +L ++EE+ ++Q ++ +E EERL +  ++ E+
Sbjct: 549 LLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLK-REQEERLEQRLKREEV 607

Query: 571 LGGAGRESGSQRLPTLTP---ILQVELKSQEAQSLQQQQ 606
                 E   QRL    P     Q  LKS+E +  +QQQ
Sbjct: 608 ERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQ 646



 Score =  176 bits (446), Expect = 6e-44
 Identities = 152/567 (26%), Positives = 299/567 (52%), Gaps = 78/567 (13%)

Query: 74   ENRKRRGTKRWDEDDDLEESEDSK-QCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVK 132
            E +  RG +R      L E  + + + +E  +R    LP++E  E               
Sbjct: 774  EEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQ-------------- 819

Query: 133  SSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAV---RMG 189
               ++RQ +  EK   F +    ++  L+  E   Q + E   L+E      +    R  
Sbjct: 820  ---RRRQRREREKELQFLE----EEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQ 872

Query: 190  TYIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLE 249
             +  +L +ER      LY      E+L+++   LQE       E+ E+Q   ++ +R+ E
Sbjct: 873  KWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQE-------EEEELQREEREKRRRQE 925

Query: 250  RAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQ 309
            + +    ++QLQ E ++L +E +    +                Q+ E+ +R+++K+Q++
Sbjct: 926  QERQYREEEQLQQEEEQLLREEREKRRR----------------QERERQYRKDKKLQQK 969

Query: 310  EEKMC--EQELKIREQEEKMWRQEEKMHEQEEKI-REQEDKMWRQE-EKIREQEEKIREQ 365
            EE++   E E + R++ EK +R+EE++ ++EE++ RE+ +K  RQE E+   ++++++++
Sbjct: 970  EEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQE 1029

Query: 366  EEKMWRQE-EKIREQDEKIQEQEEEMWRQEEK--IREQEEKRQ----EKMWRQEKKMREQ 418
            EE++ R+E EK R Q+ + Q +EEE  +QEE+  + E+ E R+    E+ +R+E++++++
Sbjct: 1030 EEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQE 1089

Query: 419  DEKIREQEEEMWRQEEK---IRELEEMMQDQEEKLREVEEKMQEEE-EKMQEQEEKIQRQ 474
            +E++  +E E  R++E+    RE EE+ Q++E+ LRE  EK + +E E+   +EE++Q++
Sbjct: 1090 EEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQE 1149

Query: 475  EEKI-QEQEEKTWRQE---------KLLKQEEKIWEQEEKMWRQE-EKMWEQEEKMQEQE 523
            EE++ +E+ EK  RQE         +L ++EE++  +E++  RQE E+ + +EE++Q Q+
Sbjct: 1150 EEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQK 1209

Query: 524  EKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQR- 582
             K + ++E  R      W+ E   +E  VR  ++  +  +  Q  +L     R+  SQ+ 
Sbjct: 1210 RKQRYRDEDQRSDLKWQWEPE---KENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQD 1266

Query: 583  LPTLTPILQVELKSQEAQSLQQQQDHY 609
            L  L    Q   + QE +  QQ+  H+
Sbjct: 1267 LQHLLGEQQERDREQERRRWQQRDRHF 1293



 Score =  174 bits (441), Expect = 2e-43
 Identities = 165/650 (25%), Positives = 332/650 (51%), Gaps = 91/650 (14%)

Query: 40   EQQSKVRNKGHGKPREKSIADEKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQC 99
            E+  + R K   K  ++    E++ +L E E   +  +R    R ++++  E+    ++ 
Sbjct: 465  ERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEE 524

Query: 100  KESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPW 159
            +E L++   +       ++     + K  +E +   ++R++++  +    R +++ ++  
Sbjct: 525  EERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEE 584

Query: 160  LRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTK-ERDAPSLELYRNTITDEELKE 218
             R   +   KR +   LE+ L  +   R+     +  + +R+ P  E  +  +  EE +E
Sbjct: 585  RRQQRL---KREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEE 641

Query: 219  ------------------KNAELQEKL-----RLVESEKSEIQLNVKDLKRKLERAQLLL 255
                              K  E +E+L     R  E E+ E +L  ++ ++  ER +  +
Sbjct: 642  RRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRI 701

Query: 256  P--QQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKM 313
            P  Q QL+ EAD    ++ S   K + Q           Q+QEEK  R+E ++Q QEE+ 
Sbjct: 702  PKWQWQLESEADARQSKVYSRPRKQEGQRRR--------QEQEEKRRRRESELQWQEEER 753

Query: 314  CEQELKIREQEEKM---WRQEEKMHEQEEKI------REQEDKMWRQEEKIREQEEKIRE 364
              ++ +  EQ       W+ EEK     +++      REQ ++  R EE+ + ++  + E
Sbjct: 754  AHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPE 813

Query: 365  QEEKMWRQEEKIREQDEKIQ--EQEEEMWRQE--EKIREQEEKRQEKMWRQEKKMREQDE 420
            +EEK  R+ ++ RE+++++Q  E+EE++ R+E  ++++E+E+  QE   R+  + + +D+
Sbjct: 814  EEEKEQRRRQR-REREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQ 872

Query: 421  KIREQ-EEEMWRQ----------EEKIRELEEMMQDQEEKL---------REVEEKMQEE 460
            K R Q EEE  R+          +E++R+ ++++Q++EE+L         R+ +E+   E
Sbjct: 873  KWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYRE 932

Query: 461  EEKMQEQEEKIQRQE-EKIQEQE-EKTWRQEKLLKQEEK--IWEQEEKMWRQE--EKMWE 514
            EE++Q++EE++ R+E EK + QE E+ +R++K L+Q+E+  + E+ EK  RQE  +K  E
Sbjct: 933  EEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYRE 992

Query: 515  QEEKMQEQEEKMQRQEEKMREQE-VRLWQQEEKMQEQEV----------RLQELEERL-- 561
            +EE  QE+E+ ++ + EK R QE  R +++++++Q++E           RLQE E +   
Sbjct: 993  EEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYRE 1052

Query: 562  -GKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYR 610
              +L Q+ E L G  RE+  ++        + EL+ +E Q L+++ +  R
Sbjct: 1053 EEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRR 1102



 Score =  173 bits (438), Expect = 5e-43
 Identities = 166/652 (25%), Positives = 340/652 (52%), Gaps = 95/652 (14%)

Query: 38  KLEQQSKVRNKGHGKPREKSIADEKFFQLSEMEAYLE--NRKRRGTKRWDEDDDLEESED 95
           +LE++   R +   + +E+ +A+ +  + SE +  LE  +R+RR  + W +  + +E E+
Sbjct: 128 QLEEEPGQRRRQKRQEQERELAEGE--EQSEKQERLEQRDRQRRDEELWRQRQEWQEREE 185

Query: 96  SKQCKESLKRV----TFTLPDDEAIEDAGVSHVK-KNSDEVKSSFKKRQEKM--NEKNYT 148
            +  +E L+      T   PD+E +    +  ++ K  +E +   ++RQ+++   E+   
Sbjct: 186 RRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKE 245

Query: 149 FRKR-VVIKKPWLRLGEVTAQKRPENSLLEETLHF--DHAVRMGTYIEKLTKERDAPSLE 205
           +RKR  V++K   +L E   Q++ E    EE L       +R     E+  ++R     +
Sbjct: 246 WRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQ 305

Query: 206 LYRNTITDEELKEKNAELQEKLRLVESEKSEIQLN-------VKDLKRKLE---RAQLLL 255
           L R    +   +++    Q++ R  + E+ E QL         + L+R+ E   R Q L 
Sbjct: 306 LRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLR 365

Query: 256 PQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCE 315
            +Q+ +    +L +E Q    + + Q+   +      Q + E+  R+E++++ +++   E
Sbjct: 366 REQEEERREQQLRREQQ---LRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 422

Query: 316 QELKIREQEEKMWRQEEKMHEQEEKI-REQEDKM-W--------RQEEKIREQEEKIREQ 365
           Q+L+ REQEE+   Q+ +   +E+++ REQE++  W        R E++ R+Q+ K  ++
Sbjct: 423 QQLR-REQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQE 481

Query: 366 EEKMWR----QEEKIREQDEKIQEQ---------EEEMWRQEEK-------------IRE 399
           EE+  R    +EE+ REQ E+ ++Q         E+ + RQEE+              RE
Sbjct: 482 EERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRRE 541

Query: 400 QEEKRQEKMWRQEKKMREQDEK----IREQEE---EMWRQEEKIRELEEMMQDQEEKLRE 452
           QEE+R++ + R+E+K  EQ+ +     REQEE   ++ ++EE+ R+ + + ++QEE+L  
Sbjct: 542 QEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQ-QRLKREQEERL-- 598

Query: 453 VEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKM 512
            E++++ EE +  EQEE   R+E++++ +E +  R+++LLK EE+   +++++ R++++ 
Sbjct: 599 -EQRLKREEVERLEQEE---RREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQER 654

Query: 513 WEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKL-------- 564
            EQ  K +E+EE+++++ ++  E+E R  +QE   +EQE   + ++ R+ K         
Sbjct: 655 REQRLKREEEEERLEQRLKREHEEERR--EQELAEEEQEQARERIKSRIPKWQWQLESEA 712

Query: 565 -GQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQQ 615
             +++++     ++ G +R        + E K +  +S  Q Q+  R H QQ
Sbjct: 713 DARQSKVYSRPRKQEGQRRRQ------EQEEKRRRRESELQWQEEERAHRQQ 758



 Score =  171 bits (434), Expect = 1e-42
 Identities = 156/533 (29%), Positives = 298/533 (55%), Gaps = 77/533 (14%)

Query: 129 DEVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRM 188
           D  +S  + R+++ +++ +  R R + ++P    G+   QKR E     E    +     
Sbjct: 104 DGKESLLQDRRQEEDQRRFEPRDRQLEEEP----GQRRRQKRQEQE--RELAEGEEQSEK 157

Query: 189 GTYIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRK- 247
              +E+  ++R     EL+R     +E +E+ AE +E+L+  +  ++E   + + L+R+ 
Sbjct: 158 QERLEQ--RDRQRRDEELWRQRQEWQEREERRAE-EEQLQSCKGHETEEFPDEEQLRRRE 214

Query: 248 ---LERAQLLLPQQQLQVEADRLGKE--------LQSVSAKLQAQVEENELWNLLNQQQE 296
              L R      QQQ +   DR+ +E         ++V  K + +++E E       Q+E
Sbjct: 215 LLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEE 274

Query: 297 E----KMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQE 352
           E    K+ RQE + + QEE+  +Q+ ++R +++   +QEE+  EQ+E+ REQ+++  +QE
Sbjct: 275 EEQLRKLERQELRRERQEEE--QQQQRLRREQQLRRKQEEERREQQEERREQQERREQQE 332

Query: 353 EKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQ----EEEMWRQEEKIREQEEKRQEKM 408
           E+ REQ+ + REQEE+  R+++  REQ+E+ +EQ    E+E  R+E+++R +++ R+E+ 
Sbjct: 333 ER-REQQLR-REQEER--REQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQ 388

Query: 409 WRQEKKMREQDEKIREQE---EEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKM- 464
            R+E+++R + +  REQ+   E+  R+E+++R  +++ ++QEE+  E + + +  E+++ 
Sbjct: 389 LRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLK 448

Query: 465 QEQEEK---IQRQEEKIQEQEEK----------TWRQEKLLK-QEEKIWEQEEK----MW 506
           +EQEE+   ++R+EE  + ++E+            R+E+ LK +EE+  EQ+E+    + 
Sbjct: 449 REQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLR 508

Query: 507 RQEEKMWEQEEKMQEQEEKMQR----QEEKMREQEVR----LWQQEEKMQEQEVRLQEL- 557
           R++E+  EQ  K QE+EE++Q+    +++  REQE R    L ++EEK  EQE R Q L 
Sbjct: 509 REQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLK 568

Query: 558 ---EERLGKLGQKAELLGGAGRESGSQRLP-TLTPILQVELKSQEAQSLQQQQ 606
              EER  +L ++ E       E   QRL       L+  LK +E + L+Q++
Sbjct: 569 REQEERRDQLLKREE-------ERRQQRLKREQEERLEQRLKREEVERLEQEE 614



 Score =  171 bits (432), Expect = 3e-42
 Identities = 154/571 (26%), Positives = 296/571 (51%), Gaps = 82/571 (14%)

Query: 40   EQQSKVRNKGHGKPREKSIADEKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQC 99
            E++ K + +   + REK +      Q  E E  L+ R+ R  +  +E+D L+E ++ ++ 
Sbjct: 813  EEEEKEQRRRQRREREKEL------QFLEEEEQLQ-RRERAQQLQEEEDGLQEDQERRRS 865

Query: 100  KESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPW 159
            +E  +   +    +E  E     H       ++   +K Q+ + E+    ++    K+  
Sbjct: 866  QEQRRDQKWRWQLEE--ERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKR-- 921

Query: 160  LRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEELKEK 219
             R  E   Q R E  L +E    +  +R     E+  K R       YR    D++L++K
Sbjct: 922  -RRQEQERQYREEEQLQQEE---EQLLR-----EEREKRRRQERERQYRK---DKKLQQK 969

Query: 220  NAEL----QEKLRLVESEKS-----EIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKE 270
              +L     EK R  E EK      E+Q   + L R+    +     ++   + D L +E
Sbjct: 970  EEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQE 1029

Query: 271  LQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMC--EQELKIREQEEKMW 328
             + +   L+ + E+  L      Q+ E+ +R+EE++Q++EE++   E+E + R++ E+ +
Sbjct: 1030 EEQL---LREEREKRRL------QERERQYREEEELQQEEEQLLGEERETRRRQELERQY 1080

Query: 329  RQEEKMHEQEEKI-REQEDKMWRQEEK--IREQEEKIREQEEKMWRQEEKIREQDEKIQE 385
            R+EE++ ++EE++ RE+ +K  RQE +   RE+EE  +E+E+ +  + EK R Q+ + Q 
Sbjct: 1081 RKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQY 1140

Query: 386  QEEEMWRQEEK--IREQEEKRQ----EKMWRQEKKMREQDEKIREQEEEMWRQE-EKIRE 438
            +EEE  +QEE+  +RE+ EKR+    E+ +R+E+++++++E++  +E+E  RQE E+   
Sbjct: 1141 REEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYR 1200

Query: 439  LEEMMQDQEEKLREVEE------KMQEEEEKM------------QEQEEKIQRQEEKIQE 480
             EE +Q Q+ K R  +E      K Q E EK             +E E+  Q ++ ++++
Sbjct: 1201 EEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRD 1260

Query: 481  QEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEK------MQRQEEKM- 533
            ++ +   Q  L +Q+E+  EQE + W+Q ++ + +EE+++ +E+K       + QEEK  
Sbjct: 1261 RQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQL 1320

Query: 534  ----REQEVRLWQQEEKMQEQEVRLQELEER 560
                RE++ R  + + K +E+E  LQE EE+
Sbjct: 1321 LREEREEKRRRQETDRKFREEEQLLQEREEQ 1351



 Score =  167 bits (422), Expect = 4e-41
 Identities = 166/682 (24%), Positives = 327/682 (47%), Gaps = 135/682 (19%)

Query: 48   KGHGKPREKSIADEKFFQLSEMEAYLENRKRRGTKRWDED----DDLEESEDS----KQC 99
            K   + REK   +E+  Q  E +   E R++R  + W+      D+L++ E+     ++ 
Sbjct: 980  KRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREERE 1039

Query: 100  KESLKRVTFTLPDDEAIEDA-----GVSHVKKNSDEVKSSFKKRQEKMNEKNYTFRKRVV 154
            K  L+       ++E ++       G     +   E++  ++K +E   E+    R+   
Sbjct: 1040 KRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPE 1099

Query: 155  IKKPWLRLGEVTAQKRPENSLLEET---LHFDHAVRMGTYIEKLTKERDAPSLELYRNTI 211
             +    R  E   Q R E  L +E    L  +   R    +E+  +E +    E     +
Sbjct: 1100 KR----RRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQE-EEQLL 1154

Query: 212  TDEELKEKNAELQEKLRLVES--EKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRL-- 267
             +E  K +  EL+ + R  E   ++ E  L  +  KR+ ER +    +++LQ +  +   
Sbjct: 1155 REEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRY 1214

Query: 268  -----------------------------GKE----LQSVSAKLQAQVEENELWNLLNQQ 294
                                         G+E     Q   ++L+ +  + +L +LL +Q
Sbjct: 1215 RDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQ 1274

Query: 295  QEE------KMWRQ-------EEKIQEQEEKMC---------EQELKIREQEEKMWRQE- 331
            QE       + W+Q       EE+++ +E+K           E++L   E+EEK  RQE 
Sbjct: 1275 QERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQET 1334

Query: 332  -EKMHEQEEKIREQEDKMWRQEE---KIREQEEKIREQEEKMWRQEEKIREQDEKIQEQE 387
              K  E+E+ ++E+E++  R++E   K RE+E + +EQ  K   +E+++R      QE+E
Sbjct: 1335 DRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRR-----QERE 1389

Query: 388  EEMWRQEEKIREQEEKRQ-----EKMWRQEKKM---REQDEKIREQEEEMWRQEEKIREL 439
             +  ++E+++R QE ++Q     ++ +R+E++    +E+D K RE+E+++ RQE + + L
Sbjct: 1390 RKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFL 1449

Query: 440  EE---MMQDQEEKLREVEEKMQEEEEKM---QEQEEKIQRQEEKIQEQE-EKTWRQEKLL 492
            EE   + Q++  K RE E+ +QE EE+    QE++ K   +E++++ QE ++ +R+++L 
Sbjct: 1450 EEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELR 1509

Query: 493  KQ--EEKIWEQEEKMWRQ--EEKMWEQEEKMQEQEEKMQRQEE---KMREQEVRLWQQEE 545
             Q  E K  E+E+++ RQ  + K  ++E++++ QE   QR+++   K RE+E    ++EE
Sbjct: 1510 SQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREE 1569

Query: 546  ------------KMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVE 593
                        +++EQ+VR QE E +  +  Q+        R+ G Q+L       + +
Sbjct: 1570 QQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLR------RQEGQQQLRQ-----ERD 1618

Query: 594  LKSQEAQSLQQQQDHYRGHLQQ 615
             K +E + L Q+++  + H Q+
Sbjct: 1619 RKFREDEQLLQEREEQQLHRQE 1640



 Score =  164 bits (415), Expect = 2e-40
 Identities = 163/671 (24%), Positives = 319/671 (47%), Gaps = 104/671 (15%)

Query: 18  DPTKSPVLSDEDSDLDFHINKLEQQSKVRNKGHGKPREKSIADEKFFQLSEMEAYLENRK 77
           +P +   L +E+  L     KLE+Q   R +   + +++ +  E+  +  + E   E ++
Sbjct: 264 EPQRQRELQEEEEQL----RKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQE 319

Query: 78  RRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSFKK 137
            R  ++   +   E  E   + ++  +R      + E  E+     +++  +E +   + 
Sbjct: 320 ERREQQERREQQEERREQQLRREQEERREQQLRREQE--EERREQQLRREQEEERREQQL 377

Query: 138 RQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTK 197
           R+E+   +    R+   +++   +L      +R +    E+ L  +  +R      +  +
Sbjct: 378 RREQQLRREQQLRREQQLRREQ-QLRREQQLRREQQLRREQQLRREQQLR-----REQEE 431

Query: 198 ERDAPSLELYRNTITDEELKEKNAELQEKL-RLVESEKSEIQLNVKDLKRKLERAQLLLP 256
           ER     E  R    ++ LK +  E ++ L R  E+E+ E +   + LKR  E  +    
Sbjct: 432 ERHEQKHEQERR---EQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERR--- 485

Query: 257 QQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMW---RQEEKIQEQEEKM 313
           ++ L++E +   ++ +    +L+ + EE     L  Q++EE++    R E++++ ++E+ 
Sbjct: 486 ERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEER 545

Query: 314 CEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWR-- 371
            EQ LK   +EEK   QE +    + +  E+ D++ ++EE+ R+Q  K REQEE++ +  
Sbjct: 546 REQLLK--REEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLK-REQEERLEQRL 602

Query: 372 --------QEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIR 423
                   ++E+ REQ  K +E EEE  +Q  K  EQEE+RQ+++ R++++ REQ  K  
Sbjct: 603 KREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKRE 662

Query: 424 EQEEEMW----RQEEKIRELEEMMQDQEEKLRE-------------------------VE 454
           E+EE +     R+ E+ R  +E+ ++++E+ RE                           
Sbjct: 663 EEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSR 722

Query: 455 EKMQEEEEKMQEQEEKIQRQEEKIQEQEEK---------------TWRQEKLLKQEE--- 496
            + QE + + QEQEEK +R+E ++Q QEE+               TW+ +   K E    
Sbjct: 723 PRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQ 782

Query: 497 ------KIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKM-REQEVRLWQQEEKMQE 549
                  + EQ E+  R EE+   ++  + E+EEK QR+ ++  RE+E++  ++EE++Q 
Sbjct: 783 RLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQR 842

Query: 550 QEVRLQELEERLGKLGQKAELLGGAGR-----------ESGSQRLPTL--TPILQVELKS 596
           +E R Q+L+E    L +  E      +           E   +R  TL   P LQ +L+ 
Sbjct: 843 RE-RAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLR- 900

Query: 597 QEAQSLQQQQD 607
           +E Q LQ++++
Sbjct: 901 KEQQLLQEEEE 911



 Score =  161 bits (407), Expect = 2e-39
 Identities = 157/679 (23%), Positives = 315/679 (46%), Gaps = 117/679 (17%)

Query: 19   PTKSPVLSDEDSDLDFHINKLEQQSKVRNKGHGKPREKSIADEKFFQLSEMEAYLENRKR 78
            P +  +  +E  +      K +++ ++  +   + R +   D KF    E E  L+ R+ 
Sbjct: 1294 PEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKF---REEEQLLQEREE 1350

Query: 79   RGTKRWDED-----DDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKS 133
            +  +R + D     ++L   E  ++  E  +R+     + + +++      ++   +++ 
Sbjct: 1351 QPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQ 1410

Query: 134  SFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIE 193
                R  K  E+     ++   +K      +V  Q+R    L EE        R     E
Sbjct: 1411 D---RDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEE 1467

Query: 194  KLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKS--EIQLNVKDLKRKLERA 251
            +L +ER+   L         +E   K  E +++LR  E ++   E +L  ++ +RK    
Sbjct: 1468 QLLQEREEQQLHR-------QERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEE 1520

Query: 252  QLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEE 311
            +  L +QQ Q       ++      +L+ Q    +      +Q  ++ +R+EE+++++ E
Sbjct: 1521 EQQLHRQQRQ-------RKFLQEEQQLRRQERGQQ-----RRQDRDRKFREEEQLRQERE 1568

Query: 312  KMCEQELKIREQEEKMWRQEEKMH--EQEEKIREQEDKMWRQE----------EKIREQE 359
               EQ+L  +E++ K   +E+K+   EQE K  E E ++ RQE           K RE E
Sbjct: 1569 ---EQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDE 1625

Query: 360  EKIREQEEKMWRQEE---------------------------KIREQDEKIQEQEEEMWR 392
            + ++E+EE+   ++E                           K RE+++ +QE EE+  R
Sbjct: 1626 QLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLR 1685

Query: 393  QEEKIRE-QEEKRQEKMWRQEKKMREQDEKIREQE-EEMWRQEEKIR-ELEEMMQDQEEK 449
            ++E+ R+ +EE++Q +   +E+K  ++++++R QE E  +R+EE++R E E+    ++E+
Sbjct: 1686 RQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQER 1745

Query: 450  LREVEEKMQ------EEEEKMQEQEEKIQRQEEKIQEQEEKTWRQE----KLLKQEEKIW 499
             R++ E+ Q      E++ + QE++ K + +E+  QE+EE+  R +    K  ++E+   
Sbjct: 1746 YRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQ 1805

Query: 500  EQEEKMWRQEEK----MWEQEEKMQEQEEKMQRQE--------------EKMREQEVRLW 541
            E+EE+  R +++     WE+E+   E++E+  RQE              EK R +E  LW
Sbjct: 1806 EREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELW 1865

Query: 542  QQEE---------KMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQV 592
            Q+EE         K++E+ +R Q+ EE+  +  Q  E+    G+  G    P       V
Sbjct: 1866 QEEEQKRRQERERKLREEHIRRQQKEEQRHR--QVGEIKSQEGKGHGRLLEPGTHQFASV 1923

Query: 593  ELKSQEA-QSLQQQQDHYR 610
             ++S    + +Q+Q+  YR
Sbjct: 1924 PVRSSPLYEYIQEQRSQYR 1942



 Score =  151 bits (381), Expect = 2e-36
 Identities = 128/459 (27%), Positives = 259/459 (56%), Gaps = 59/459 (12%)

Query: 217 KEKNAELQEKLRLVESEKSEI-QLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVS 275
           +EK A    K  L++  + E  Q   +   R+LE       +Q+ Q E +R   E +  S
Sbjct: 97  EEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQ-EQERELAEGEEQS 155

Query: 276 AKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQEL--KIREQEEKMWRQEEK 333
            K Q ++E+ +      Q+++E++WRQ ++ QE+EE+  E+E     +  E + +  EE+
Sbjct: 156 EK-QERLEQRD-----RQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQ 209

Query: 334 MHEQE-----EKIRE--QEDKMWRQEEKIREQEEK-IREQEEKMWRQEEKIREQD----E 381
           +  +E      K RE  Q+ +  RQ+   +E+EEK  R++E  + ++EEK++E++     
Sbjct: 210 LRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQR 269

Query: 382 KIQEQEEEMWRQE----EKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIR 437
           ++QE+EE++ + E     + R++EE++Q+++ R+++  R+Q+E+ REQ+EE   Q+E+  
Sbjct: 270 ELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERRE 329

Query: 438 ELEE-----------------MMQDQEEKLREVEEKMQEEEEKMQEQ---EEKIQRQEEK 477
           + EE                 + ++QEE+ RE + + ++EEE+ ++Q   E++++R+++ 
Sbjct: 330 QQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQL 389

Query: 478 IQEQE---EKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKM- 533
            +EQ+   E+  R+E+ L++E+++  +E+++ R+++   EQEE+  EQ+ + +R+E+++ 
Sbjct: 390 RREQQLRREQQLRREQQLRREQQL-RREQQLRREQQLRREQEEERHEQKHEQERREQRLK 448

Query: 534 REQEVRL-W---QQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPI 589
           REQE R  W   ++E +  EQE R Q+L+    +  ++ E       E   ++       
Sbjct: 449 REQEERRDWLKREEETERHEQERRKQQLKR--DQEEERRERWLKLEEEERREQQERREQQ 506

Query: 590 LQVELKSQEAQSLQQQQDHYRGHLQQYVAAYQQLASGKE 628
           L+ E + +  Q L++Q++  R  LQQ + + QQL   +E
Sbjct: 507 LRREQEERREQRLKRQEEEER--LQQRLRSEQQLRREQE 543



 Score =  143 bits (361), Expect = 4e-34
 Identities = 105/355 (29%), Positives = 206/355 (58%), Gaps = 36/355 (10%)

Query: 291 LNQQQEEKMWRQEEKIQEQEEKMCEQELKIRE---QEEKMWRQEEKMHEQEEKIREQEDK 347
           L++++  +   +E  +Q++ ++  ++  + R+   +EE   R+ +K  EQE ++ E E++
Sbjct: 95  LDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQ 154

Query: 348 MWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEE---------EMWRQEEKIR 398
             +QE    EQ ++ R  EE +WRQ ++ +E++E+  E+E+         E +  EE++R
Sbjct: 155 SEKQERL--EQRDRQRRDEE-LWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLR 211

Query: 399 EQ---EEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEE 455
            +   E +R+ +  +Q+++   QD   +E+EE+ WR+ E +   EE    +EE  R+ E 
Sbjct: 212 RRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRE- 270

Query: 456 KMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLL--KQEEKIWEQEEKMWRQEEKMW 513
            +QEEEE++++ E +  R+E + +EQ+++  R+E+ L  KQEE+  EQ+E+   Q+E+  
Sbjct: 271 -LQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERRE 329

Query: 514 EQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGG 573
           +QEE+   +E++++R++E+ REQ++R  Q+EE+ ++Q  R QE E R  +L ++ +L   
Sbjct: 330 QQEER---REQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQL--- 383

Query: 574 AGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQQYVAAYQQLASGKE 628
             RE   +R       L+ E + +  Q L+++Q   R   +Q +   QQL   +E
Sbjct: 384 -RREQQLRR----EQQLRREQQLRREQQLRREQQLRR---EQQLRREQQLRREQE 430


>gi|31317305 M-phase phosphoprotein 10 [Homo sapiens]
          Length = 681

 Score =  176 bits (447), Expect = 5e-44
 Identities = 144/469 (30%), Positives = 233/469 (49%), Gaps = 54/469 (11%)

Query: 2   GGDNPEVSERANSSKFDPTKSPVLSDEDSDLDFHINKLEQQSKVRNKGHGKPREKSIADE 61
           G    +  + + + K+     PV SDED   + H ++L+   +          +  IA+E
Sbjct: 251 GSKKLKSGKSSRNLKYKDFFDPVESDEDIT-NVHDDELDSNKE----------DDEIAEE 299

Query: 62  KFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGV 121
           +  +LS  E              DEDDDL+E+ED+KQ KESLKRVTF LPDD   ED GV
Sbjct: 300 EAEELSISET-------------DEDDDLQENEDNKQHKESLKRVTFALPDDAETEDTGV 346

Query: 122 SHVKKNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLH 181
            +VKKNSDEVKSSF+KRQEKMNEK  +  K ++ KKPW   GEVTAQKRPENSLLEETLH
Sbjct: 347 LNVKKNSDEVKSSFEKRQEKMNEKIASLEKELLEKKPWQLQGEVTAQKRPENSLLEETLH 406

Query: 182 FDHAVRMGTYI--------EKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESE 233
           FDHAVRM   I        E + K+R     + + + +  E+ KE   E +++L L + E
Sbjct: 407 FDHAVRMAPVITEETTLQLEDIIKQRIRD--QAWDDVVRKEKPKEDAYEYKKRLTL-DHE 463

Query: 234 KSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQ 293
           KS++      L    E+  + L QQ+   E +    E+Q +   L  +++    ++ +  
Sbjct: 464 KSKL-----SLAEIYEQEYIKLNQQKTAEEENPEHVEIQKMMDSLFLKLDALSNFHFI-- 516

Query: 294 QQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEE 353
                      K    E K+      I  +E       +      E+I+E+      +  
Sbjct: 517 ----------PKPPVPEIKVVSNLPAITMEEVAPVSVSDAALLAPEEIKEKNKAGDIKTA 566

Query: 354 KIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEK 413
             +   +K RE+ +K +++  KI+E++++ +  E+    Q  K    +    EK+ +  K
Sbjct: 567 AEKTATDKKRERRKKKYQKRMKIKEKEKRRKLLEKSSVDQAGKY--SKTVASEKLKQLTK 624

Query: 414 KMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462
             +    K   +++ +   +    +L++ ++ Q    ++ E+K ++ ++
Sbjct: 625 TGKASFIKDEGKDKALKSSQAFFSKLQDQVKMQINDAKKTEKKKKKRQD 673



 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 82/436 (18%), Positives = 193/436 (44%), Gaps = 71/436 (16%)

Query: 199 RDAPSLELYRN----TITDEELKE-KNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQL 253
           ++ P L+ ++N    TI DE++     +E QE+    E + SEI+ + K+    LE  ++
Sbjct: 83  QNEPILQYFQNAVSETINDEDISLLPESEEQER----EEDGSEIEADDKEDLEDLEEEEV 138

Query: 254 LLPQQQLQVEADRLGK--ELQSVSAKLQAQV---EENEL-WNLLNQQQEEKMW------- 300
                 +  +   +G+  E  S S   ++ V   E+++L +++   +Q+ K+        
Sbjct: 139 ----SDMGNDDPEMGERAENSSKSDLRKSPVFSDEDSDLDFDISKLEQQSKVQNKGQGKP 194

Query: 301 RQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQE-----EKIREQED--------- 346
           R++  + ++  K+ E E  +   E++  R+++   E+E     E I   ED         
Sbjct: 195 REKSIVDDKFFKLSEMEAYLENIEKEEERKDDNDEEEEDIDFFEDIDSDEDEGGLFGSKK 254

Query: 347 -KMWRQEEKIREQE--EKIREQEEKMWRQEEKI---REQDEKIQEQEEEM----WRQEEK 396
            K  +    ++ ++  + +   E+     ++++   +E DE  +E+ EE+      +++ 
Sbjct: 255 LKSGKSSRNLKYKDFFDPVESDEDITNVHDDELDSNKEDDEIAEEEAEELSISETDEDDD 314

Query: 397 IREQEEKRQEKMWRQEKKMREQDEKIREQEEEM---WRQEEKIRELEEMMQDQEEKLREV 453
           ++E E+ +Q K   +       D+   E    +      +E     E+  +   EK+  +
Sbjct: 315 LQENEDNKQHKESLKRVTFALPDDAETEDTGVLNVKKNSDEVKSSFEKRQEKMNEKIASL 374

Query: 454 EEKMQEEEE-KMQEQEEKIQRQEEKIQEQ---------------EEKTWRQEKLLKQE-- 495
           E+++ E++  ++Q +    +R E  + E+               EE T + E ++KQ   
Sbjct: 375 EKELLEKKPWQLQGEVTAQKRPENSLLEETLHFDHAVRMAPVITEETTLQLEDIIKQRIR 434

Query: 496 EKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQ 555
           ++ W+   +  + +E  +E ++++    EK +    ++ EQE     Q++  +E+     
Sbjct: 435 DQAWDDVVRKEKPKEDAYEYKKRLTLDHEKSKLSLAEIYEQEYIKLNQQKTAEEENPEHV 494

Query: 556 ELEERLGKLGQKAELL 571
           E+++ +  L  K + L
Sbjct: 495 EIQKMMDSLFLKLDAL 510



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 55/257 (21%), Positives = 115/257 (44%), Gaps = 25/257 (9%)

Query: 324 EEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIR---EQEEKIREQEEKMWRQEEKIREQD 380
           +E++W+Q E  +E   +  +        +E I    E EE+ RE++      ++K  E  
Sbjct: 73  DEQIWQQLELQNEPILQYFQNAVSETINDEDISLLPESEEQEREEDGSEIEADDK--EDL 130

Query: 381 EKIQEQE-EEMWRQEEKIREQEEKRQEKMWRQEKKMREQDE-------KIREQEEEMWRQ 432
           E ++E+E  +M   + ++ E+ E   +   R+     ++D        K+ +Q +   + 
Sbjct: 131 EDLEEEEVSDMGNDDPEMGERAENSSKSDLRKSPVFSDEDSDLDFDISKLEQQSKVQNKG 190

Query: 433 EEKIRELEEMMQDQEEKLREVE------EKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTW 486
           + K RE + ++ D+  KL E+E      EK +E ++   E+EE I   E+   +++E   
Sbjct: 191 QGKPRE-KSIVDDKFFKLSEMEAYLENIEKEEERKDDNDEEEEDIDFFEDIDSDEDEGGL 249

Query: 487 RQEKLLKQEE-----KIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLW 541
              K LK  +     K  +  + +   E+     ++++   +E  +  EE+  E  +   
Sbjct: 250 FGSKKLKSGKSSRNLKYKDFFDPVESDEDITNVHDDELDSNKEDDEIAEEEAEELSISET 309

Query: 542 QQEEKMQEQEVRLQELE 558
            +++ +QE E   Q  E
Sbjct: 310 DEDDDLQENEDNKQHKE 326


>gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo
           sapiens]
          Length = 693

 Score =  155 bits (392), Expect = 1e-37
 Identities = 109/424 (25%), Positives = 228/424 (53%), Gaps = 38/424 (8%)

Query: 164 EVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEELK--EKNA 221
           E   Q+R + ++ E  L   H  ++   ++++  ERD      Y   I  E  +  E+  
Sbjct: 194 EAVLQRRLQQTIKERALLNAHVTQVTESLKQVQLERDE-----YAKHIKGERARWQERMW 248

Query: 222 ELQEKLRLVESEKS-------EIQLNVKDLKRKLERAQLLLPQ------QQLQVEADRLG 268
           ++  + R ++ EK        E++ ++ +LK ++     L P       +QLQ EA  L 
Sbjct: 249 KMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLR 308

Query: 269 KELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMW 328
           +E++ +  KLQ+QVE N+  +LL+++Q++++  QEE ++EQE +   ++ ++ EQ E++ 
Sbjct: 309 QEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLR 368

Query: 329 RQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEE 388
            Q++ + EQ E++R+QE ++ +QEE++R++EE++++QE+++W QEE++ +++E++Q+QEE
Sbjct: 369 EQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEE 428

Query: 389 EM-WRQEEKIREQEEKRQ---EKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQ 444
            +   Q  K+ +Q  + Q   E +  ++K   + +++++E +E++   EE +    +  Q
Sbjct: 429 RLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKL--DEEHLEAASQRNQ 486

Query: 445 DQEEKLREVEEKMQ-EEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEE 503
             E +L  V    + +  + +  +EE+  R    I E  E        +   ++  +  E
Sbjct: 487 QLETQLSLVALPGEGDGGQHLDSEEEEAPRPTPNIPEDLESREATSSFMDLPKEKADGTE 546

Query: 504 KMWRQE----------EKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVR 553
           ++ R+E          + M E     + Q      + ++M E  +RL Q+EE+M+ + + 
Sbjct: 547 QVERRELGFVQPSGVTDGMRESFTVYESQGAVPNTRHQEM-EDVIRLAQKEEEMKVKLLE 605

Query: 554 LQEL 557
           LQEL
Sbjct: 606 LQEL 609



 Score =  146 bits (368), Expect = 7e-35
 Identities = 124/521 (23%), Positives = 254/521 (48%), Gaps = 59/521 (11%)

Query: 136 KKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKL 195
           + RQ K+       ++    K P +  G  T +K+ ++S    T    H+     Y ++L
Sbjct: 16  ESRQNKLAAAKKKLKEYQQRKSPGIPAGAKTKKKKTDSSPETTTSGGGHSPGDSQY-QEL 74

Query: 196 TKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEI-QLNVKDLKR----KLER 250
               ++ S+ + +     E LK++  +++ +L   +   +EI +  ++ L+      LE+
Sbjct: 75  AVALESSSVTINQLNENIESLKQQKKQVEHQLEEAKKTNNEIHKAQMEQLETINILTLEK 134

Query: 251 AQLLLPQQQLQVEADRLGKELQSVSAKLQAQVE-----ENELWNLLNQQQEEKMWRQEEK 305
           A L       +  A    +E + ++ +LQ  ++     E  L  +  QQQEE   R    
Sbjct: 135 ADLKTTLYHTKRAARHFEEESKDLAGRLQYSLQHIQELERALCAVSTQQQEED--RSSSC 192

Query: 306 IQEQEEKMCEQELKIRE-------------QEEKMWRQEEKMHEQEEKIREQEDKMWRQE 352
            +   ++  +Q +K R              ++ ++ R E   H + E+ R QE +MW+  
Sbjct: 193 REAVLQRRLQQTIKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERARWQE-RMWKMS 251

Query: 353 EKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQE-----------EEMWRQEEKIREQE 401
            + R  +E+ +    ++   E  + E   ++ E             E++  + + +R++ 
Sbjct: 252 VEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQEV 311

Query: 402 EKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEE 461
           E  + K+  Q +  +      +EQ++ +  QEE +RE E     ++E+L E  E+++E++
Sbjct: 312 EGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQ 371

Query: 462 EKMQEQEEKIQRQEEKIQEQEEKTWRQE-KLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQ 520
           + +QEQ E++++QE+++++QEE+  ++E +L KQE+++W+QEE++W++EE++ +QEE++ 
Sbjct: 372 KTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLA 431

Query: 521 -EQEEKMQRQ-------------EEKMR---EQEVRLWQQ---EEKMQEQEVRLQELEER 560
             Q  K+ +Q             E+K     EQ+V+  Q+   EE ++    R Q+LE +
Sbjct: 432 LSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASQRNQQLETQ 491

Query: 561 LGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQS 601
           L  +    E  GG   +S  +  P  TP +  +L+S+EA S
Sbjct: 492 LSLVALPGEGDGGQHLDSEEEEAPRPTPNIPEDLESREATS 532


>gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C
           isoform 1 [Homo sapiens]
          Length = 693

 Score =  155 bits (392), Expect = 1e-37
 Identities = 109/424 (25%), Positives = 228/424 (53%), Gaps = 38/424 (8%)

Query: 164 EVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEELK--EKNA 221
           E   Q+R + ++ E  L   H  ++   ++++  ERD      Y   I  E  +  E+  
Sbjct: 194 EAVLQRRLQQTIKERALLNAHVTQVTESLKQVQLERDE-----YAKHIKGERARWQERMW 248

Query: 222 ELQEKLRLVESEKS-------EIQLNVKDLKRKLERAQLLLPQ------QQLQVEADRLG 268
           ++  + R ++ EK        E++ ++ +LK ++     L P       +QLQ EA  L 
Sbjct: 249 KMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLR 308

Query: 269 KELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMW 328
           +E++ +  KLQ+QVE N+  +LL+++Q++++  QEE ++EQE +   ++ ++ EQ E++ 
Sbjct: 309 QEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLR 368

Query: 329 RQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEE 388
            Q++ + EQ E++R+QE ++ +QEE++R++EE++++QE+++W QEE++ +++E++Q+QEE
Sbjct: 369 EQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEE 428

Query: 389 EM-WRQEEKIREQEEKRQ---EKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQ 444
            +   Q  K+ +Q  + Q   E +  ++K   + +++++E +E++   EE +    +  Q
Sbjct: 429 RLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKL--DEEHLEAASQRNQ 486

Query: 445 DQEEKLREVEEKMQ-EEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEE 503
             E +L  V    + +  + +  +EE+  R    I E  E        +   ++  +  E
Sbjct: 487 QLETQLSLVALPGEGDGGQHLDSEEEEAPRPTPNIPEDLESREATSSFMDLPKEKADGTE 546

Query: 504 KMWRQE----------EKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVR 553
           ++ R+E          + M E     + Q      + ++M E  +RL Q+EE+M+ + + 
Sbjct: 547 QVERRELGFVQPSGVTDGMRESFTVYESQGAVPNTRHQEM-EDVIRLAQKEEEMKVKLLE 605

Query: 554 LQEL 557
           LQEL
Sbjct: 606 LQEL 609



 Score =  145 bits (367), Expect = 9e-35
 Identities = 124/521 (23%), Positives = 254/521 (48%), Gaps = 59/521 (11%)

Query: 136 KKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKL 195
           + RQ K+       ++    K P +  G  T +K+ ++S    T    H+     Y ++L
Sbjct: 16  ESRQNKLAAAKKKLKEYQQRKSPGIPAGAKTKKKKTDSSPETTTSGGGHSPGDSQY-QEL 74

Query: 196 TKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEI-QLNVKDLKR----KLER 250
               ++ S+ + +     E LK++  +++ +L   +   +EI +  ++ L+      LE+
Sbjct: 75  AVALESSSVTINQLNENIESLKQQKKQVEHQLEEAKKTNNEIHKAQMEQLETINILTLEK 134

Query: 251 AQLLLPQQQLQVEADRLGKELQSVSAKLQAQVE-----ENELWNLLNQQQEEKMWRQEEK 305
           A L       +  A    +E + ++ +LQ  ++     E  L  +  QQQEE   R    
Sbjct: 135 ADLKTTLYHTKRAARHFEEESKDLAGRLQYSLQRIQELERALSAVSTQQQEED--RSSSC 192

Query: 306 IQEQEEKMCEQELKIRE-------------QEEKMWRQEEKMHEQEEKIREQEDKMWRQE 352
            +   ++  +Q +K R              ++ ++ R E   H + E+ R QE +MW+  
Sbjct: 193 REAVLQRRLQQTIKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERARWQE-RMWKMS 251

Query: 353 EKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQE-----------EEMWRQEEKIREQE 401
            + R  +E+ +    ++   E  + E   ++ E             E++  + + +R++ 
Sbjct: 252 VEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQEV 311

Query: 402 EKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEE 461
           E  + K+  Q +  +      +EQ++ +  QEE +RE E     ++E+L E  E+++E++
Sbjct: 312 EGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQ 371

Query: 462 EKMQEQEEKIQRQEEKIQEQEEKTWRQE-KLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQ 520
           + +QEQ E++++QE+++++QEE+  ++E +L KQE+++W+QEE++W++EE++ +QEE++ 
Sbjct: 372 KTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLA 431

Query: 521 -EQEEKMQRQ-------------EEKMR---EQEVRLWQQ---EEKMQEQEVRLQELEER 560
             Q  K+ +Q             E+K     EQ+V+  Q+   EE ++    R Q+LE +
Sbjct: 432 LSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASQRNQQLETQ 491

Query: 561 LGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQS 601
           L  +    E  GG   +S  +  P  TP +  +L+S+EA S
Sbjct: 492 LSLVALPGEGDGGQHLDSEEEEAPRPTPNIPEDLESREATS 532


>gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo
           sapiens]
          Length = 693

 Score =  154 bits (389), Expect = 2e-37
 Identities = 108/424 (25%), Positives = 228/424 (53%), Gaps = 38/424 (8%)

Query: 164 EVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEELK--EKNA 221
           E    +R + ++ E  L   H  ++   ++++  ERD      Y   I  E  +  E+  
Sbjct: 194 EAVLHRRLQQTIKERALLNAHVTQVTESLKQVQLERDE-----YAKHIKGERARWQERMW 248

Query: 222 ELQEKLRLVESEKS-------EIQLNVKDLKRKLERAQLLLPQ------QQLQVEADRLG 268
           ++  + R ++ EK        E++ ++ +LK ++ +   L P       +QLQ EA  L 
Sbjct: 249 KMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAKPPSLAPPAVTSVVEQLQDEAKHLR 308

Query: 269 KELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMW 328
           +E++ +  KLQ+QVE N+  +LL+++Q++++  QEE ++EQE +   ++ ++ EQ E++ 
Sbjct: 309 QEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEVQRVREQERLCEQNERLR 368

Query: 329 RQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEE 388
            Q++ + EQ E++R+QE ++ +QEE++R++EE++++QE+++W QEE++ +++E++Q+QEE
Sbjct: 369 EQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEE 428

Query: 389 EM-WRQEEKIREQEEKRQ---EKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQ 444
            +   Q  K+ +Q  + Q   E +  ++K   + +++++E +E++   EE +    +  Q
Sbjct: 429 RLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKL--DEEHLEAASQQNQ 486

Query: 445 DQEEKLREVEEKMQ-EEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEE 503
             E +L  V    + +  + +  +EE+  R    I E  E        +   ++  +  E
Sbjct: 487 QLETQLSLVALPGEGDGGQHLDSEEEEAPRPTPNIPEDLESREATSSFMDLPKEKADGTE 546

Query: 504 KMWRQE----------EKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVR 553
           ++ R+E          + M E     + Q      + ++M E  +RL Q+EE+M+ + + 
Sbjct: 547 QVERRELGFVQPSGVTDGMRESFTVYESQGAVPNTRHQEM-EDVIRLAQKEEEMKVKLLE 605

Query: 554 LQEL 557
           LQEL
Sbjct: 606 LQEL 609



 Score =  143 bits (361), Expect = 4e-34
 Identities = 126/523 (24%), Positives = 260/523 (49%), Gaps = 63/523 (12%)

Query: 136 KKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKL 195
           + RQ K+       ++    K P +  G  T +K+ ++S    T    H+     Y ++L
Sbjct: 16  ESRQNKLAAAKKKLKEYQQRKSPGIPAGAKTKKKKTDSSPETTTSGGGHSPGDSQY-QEL 74

Query: 196 TKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKR-------KL 248
               ++ S+ + +     E LK++  +++ +L   E++K+  +++   ++R        L
Sbjct: 75  AVALESSSVTISQLNENIESLKQQKKQVEHQLE--EAKKTNNEIHKAQMERLETINILTL 132

Query: 249 ERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVE-----ENELWNLLNQQQEEKMWRQE 303
           E+A L       +  A    +E + ++ +LQ  ++     E  L  +  QQQEE   R  
Sbjct: 133 EKADLKTTLYHTKRAARHFEEESKDLAGRLQYSLQRIQELERALCAVSTQQQEED--RSS 190

Query: 304 EKIQEQEEKMCEQELKIRE-------------QEEKMWRQEEKMHEQEEKIREQEDKMWR 350
              +    +  +Q +K R              ++ ++ R E   H + E+ R QE +MW+
Sbjct: 191 SCREAVLHRRLQQTIKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERARWQE-RMWK 249

Query: 351 QEEKIRE-QEEKIRE--QEEKMWRQEEKIREQDEK--------IQEQEEEMWRQEEKIRE 399
              + R  +EEK R+  + +++ R   +++ Q  K        +    E++  + + +R+
Sbjct: 250 MSVEARTLKEEKKRDIHRIQELERSLSELKNQMAKPPSLAPPAVTSVVEQLQDEAKHLRQ 309

Query: 400 QEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQE 459
           + E  + K+  Q +  +      +EQ++ +  QEE +RE E     ++E+L E  E+++E
Sbjct: 310 EVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEVQRVREQERLCEQNERLRE 369

Query: 460 EEEKMQEQEEKIQRQEEKIQEQEEKTWRQE-KLLKQEEKIWEQEEKMWRQEEKMWEQEEK 518
           +++ +QEQ E++++QE+++++QEE+  ++E +L KQE+++W+QEE++W++EE++ +QEE+
Sbjct: 370 QQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEER 429

Query: 519 MQ-EQEEKMQRQ-------------EEKMR---EQEVRLWQQ---EEKMQEQEVRLQELE 558
           +   Q  K+ +Q             E+K     EQ+V+  Q+   EE ++    + Q+LE
Sbjct: 430 LALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASQQNQQLE 489

Query: 559 ERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQS 601
            +L  +    E  GG   +S  +  P  TP +  +L+S+EA S
Sbjct: 490 TQLSLVALPGEGDGGQHLDSEEEEAPRPTPNIPEDLESREATS 532


>gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo
           sapiens]
          Length = 693

 Score =  152 bits (383), Expect = 1e-36
 Identities = 108/424 (25%), Positives = 226/424 (53%), Gaps = 38/424 (8%)

Query: 164 EVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEELK--EKNA 221
           E   Q+  + ++ E  L   H  ++   ++++  ERD      Y   I  E  +  E+  
Sbjct: 194 EAVLQRWLQQTIKERALLNAHVTQVTESLKQVQLERDE-----YAKHIKGERARWQERMW 248

Query: 222 ELQEKLRLVESEKS-------EIQLNVKDLKRKLERAQLLLPQ------QQLQVEADRLG 268
           ++  + R ++ EK        E++ ++ +LK ++     L P       +QLQ EA  L 
Sbjct: 249 KMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLR 308

Query: 269 KELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMW 328
           +E++ +  KLQ+QVE N+  +LL+++Q++++  QEE ++EQE +   ++ ++ EQ E++ 
Sbjct: 309 QEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLR 368

Query: 329 RQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEE 388
            Q++ + EQ E++R+QE ++ +QEE++R++EE++++QE+++W QEE++ +++E++Q+QEE
Sbjct: 369 EQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEE 428

Query: 389 EM-WRQEEKIREQEEKRQ---EKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQ 444
            +   Q  K+ +Q  + Q   E +  ++K   + +++++E +E++   EE +       Q
Sbjct: 429 RLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKL--DEEHLEAASHQNQ 486

Query: 445 DQEEKLREVEEKMQ-EEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEE 503
             E +L  V    + +  + +  +EE+  R    I E  E        +   ++  +  E
Sbjct: 487 QLETQLSLVALPGEGDGGQHLDSEEEEAPRPTPNIPEDLESREATSSFMDLPKEKADGTE 546

Query: 504 KMWRQE----------EKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVR 553
           ++ R+E          + M E     + Q      + ++M E  +RL Q+EE+M+ + + 
Sbjct: 547 QVERRELGFVQPSGVTDGMRESFTVYESQGAVPNTRHQEM-EDVIRLAQKEEEMKVKLLE 605

Query: 554 LQEL 557
           LQEL
Sbjct: 606 LQEL 609



 Score =  144 bits (364), Expect = 2e-34
 Identities = 123/523 (23%), Positives = 256/523 (48%), Gaps = 63/523 (12%)

Query: 136 KKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKL 195
           + RQ K+       ++    K P +  G  T +K+ ++S    T    H+     Y ++L
Sbjct: 16  ESRQNKLAAAKKKLKEYQQRKSPGIPAGAKTKKKKTDSSPETTTSGGCHSPGDSQY-QEL 74

Query: 196 TKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKR-------KL 248
               ++ S+ + +     E LK++  +++ +L   E++K+  +++   ++R        L
Sbjct: 75  AVALESSSVTISQLNENIESLKQQKKQVEHQLE--EAKKTNNEIHKAQMERLETINILTL 132

Query: 249 ERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVE-----ENELWNLLNQQQEEKMWRQE 303
           E+A L       +  A    +E + ++ +LQ  ++     E  L  +  QQQEE   R  
Sbjct: 133 EKADLKTTLYHTKRAARHFEEESKDLAGRLQYSLQRIQELERALCAVSTQQQEED--RSS 190

Query: 304 EKIQEQEEKMCEQELKIRE-------------QEEKMWRQEEKMHEQEEKIREQEDKMWR 350
              +   ++  +Q +K R              ++ ++ R E   H + E+ R QE +MW+
Sbjct: 191 SCREAVLQRWLQQTIKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERARWQE-RMWK 249

Query: 351 QEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQE-----------EEMWRQEEKIRE 399
              + R  +E+ +    ++   E  + E   ++ E             E++  + + +R+
Sbjct: 250 MSVEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQ 309

Query: 400 QEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQE 459
           + E  + K+  Q +  +      +EQ++ +  QEE +RE E     ++E+L E  E+++E
Sbjct: 310 EVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLRE 369

Query: 460 EEEKMQEQEEKIQRQEEKIQEQEEKTWRQE-KLLKQEEKIWEQEEKMWRQEEKMWEQEEK 518
           +++ +QEQ E++++QE+++++QEE+  ++E +L KQE+++W+QEE++W++EE++ +QEE+
Sbjct: 370 QQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEER 429

Query: 519 MQ-EQEEKMQRQ-------------EEKMR---EQEVRLWQQ---EEKMQEQEVRLQELE 558
           +   Q  K+ +Q             E+K     EQ+V+  Q+   EE ++    + Q+LE
Sbjct: 430 LALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASHQNQQLE 489

Query: 559 ERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQS 601
            +L  +    E  GG   +S  +  P  TP +  +L+S+EA S
Sbjct: 490 TQLSLVALPGEGDGGQHLDSEEEEAPRPTPNIPEDLESREATS 532


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score =  148 bits (374), Expect = 1e-35
 Identities = 89/383 (23%), Positives = 214/383 (55%), Gaps = 35/383 (9%)

Query: 214  EELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQS 273
            E+L  +   LQE  +L   E  ++  N+   K K E+      +  L+ E  R G+E + 
Sbjct: 1501 EKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSK-EQQYKDEEEVTLEEEVSREGEEKEQ 1559

Query: 274  VSAKLQAQVEENELWNLLNQQQ---EEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQ 330
               + Q  ++E   W  +++++   E+K  ++E K+ ++EEK+ ++E ++ ++E K+ + 
Sbjct: 1560 QVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQA 1619

Query: 331  EEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEM 390
              K+ + + ++ + E K  ++EE + ++ EK+ ++ EK+ ++ +K+ ++ EK+  +EE++
Sbjct: 1620 YVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKL 1679

Query: 391  WRQ-----------EEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEE----- 434
             ++            +K+ E  ++ Q   W++++  +E +E   + EE  W++EE     
Sbjct: 1680 AKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEE 1739

Query: 435  --------KIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTW 486
                    K+ E EE +  Q EKL E E K+ +EEE + +++EK+ + +EK+ E+EE+  
Sbjct: 1740 GKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLG 1799

Query: 487  R-QEKLLKQEEKIWEQEEKMWRQEEKMWE------QEEKMQEQEEKMQRQEEKMREQEVR 539
            R +E+L++++ K+ ++ E+     E++ +      Q++ + ++++ + +++EK+ +++  
Sbjct: 1800 RKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKEN 1859

Query: 540  LWQQEEKMQEQEVRLQELEERLG 562
            L   +E++   + +L +++ +LG
Sbjct: 1860 LLYNKERLTHSKKQLVQVKNKLG 1882



 Score =  143 bits (361), Expect = 4e-34
 Identities = 127/473 (26%), Positives = 242/473 (51%), Gaps = 47/473 (9%)

Query: 121  VSHVKKNSDEVKSSFKKRQEKMNEKNY--TFRKRVVIKKPWLRLGEVTAQKRPENSLLEE 178
            ++  +K   +V+ S  K+QEK+ ++       K +V  K  LR GE+   K  +   LE 
Sbjct: 1909 LAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLR-GELDIAKEEKALNLEM 1967

Query: 179  TLHFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKL-----RLVESE 233
                +  +R+    E L+K     +    + T  ++EL E+   L+EK+     R++  E
Sbjct: 1968 KRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKILLHEDRILAME 2027

Query: 234  KSEIQLNVKDLKRKLE--RAQLLLPQQQ--LQVEADRLGKELQSVSAKLQAQVEENELWN 289
            +SEI       K KLE  R Q +  Q Q  L   + +L K+ +S+S       E  +L  
Sbjct: 2028 ESEIA------KGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSK------EPAKLNK 2075

Query: 290  LLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMW 349
            +L   Q  K+ R E K+ ++E KM + +  +  +E ++  ++ K+  +E    E+  ++ 
Sbjct: 2076 ILKALQ--KLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELT 2133

Query: 350  RQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQ---- 405
            + E+K+  ++ K+  +  +M  +EEK+ E++ K+  +  E+   +E+    EE+      
Sbjct: 2134 KDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFL 2193

Query: 406  EKMWRQEKKMREQD---EKIREQEEEMWRQEEKIRELEEMMQDQE-------EKLREVEE 455
            ++ WR+ K+ +  D   EK   Q +E+  +E    E+E ++ + E       E+  E EE
Sbjct: 2194 KRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREE 2253

Query: 456  KMQEEEEKMQEQEEKIQRQ---EEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKM 512
            + + EEE+++E+EE+ + +   EEK  E+EE+  +++K  K++E++ E+EE    +EE M
Sbjct: 2254 EEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIM 2313

Query: 513  WEQEEKM----QEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERL 561
             E+E +     +E+EE    +EE  RE+E+   +++ K+QEQ  +     ER+
Sbjct: 2314 SEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRRKSLRGRERV 2366



 Score =  138 bits (347), Expect = 2e-32
 Identities = 120/580 (20%), Positives = 285/580 (49%), Gaps = 40/580 (6%)

Query: 25   LSDEDSDLDFHINKLE--QQSKVRNKGHGKPREKSIADEKFFQLSEMEAYLENRKRRGTK 82
            ++ E+ D+   + ++   ++  V+ +G     E++ + + + +  +    +    R+  K
Sbjct: 1420 MTKEERDMSEEVEEMATLEEKVVKQEGKLVMIERTPSWQDWKKAWDEWKQVHGETRKSWK 1479

Query: 83   RWDEDDD---LEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSFKKRQ 139
             W E+ +   L+E E   Q  E L      L +D+ ++      V +N   + SS  K Q
Sbjct: 1480 AWKEEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWEN---MLSSKSKEQ 1536

Query: 140  EKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKER 199
            +  +E+  T  + V       R GE       E  + EE  H     +      K  +  
Sbjct: 1537 QYKDEEEVTLEEEVS------REGE-----EKEQQVTEEQRHIQEEHKWARIHRKRARAE 1585

Query: 200  DAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQ 259
               + E  +    +E+L       QE+ +L + E+   Q  VK  +   E AQ      Q
Sbjct: 1586 KKRAQEERKLAQEEEKLA------QEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQ 1639

Query: 260  LQVEADRLGKELQSVSAKL-QAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQEL 318
             +    + G++L   + KL Q + +  + W        EK+ R+EEK+ ++  K+ E + 
Sbjct: 1640 KEETLAQRGEKLSQEAEKLAQKRKKLAKKW--------EKVAREEEKLAKKGGKLAEVKN 1691

Query: 319  KIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIRE 378
             + ++ E++ ++E+ +  QE+++ ++ +++    E++  +EE++ ++E K+  +++K+ E
Sbjct: 1692 ILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAE 1751

Query: 379  QDEKIQEQEEEMWRQEEKIREQEE---KRQEKMWRQEKKMREQDEKIREQEEEMWRQEEK 435
            ++E +  Q E++  +E K+ ++EE   + +EK+ + ++KM E++E++  + E++  ++ K
Sbjct: 1752 EEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMK 1811

Query: 436  IRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQE 495
            + +  E   +  E+L + +  + +++   QE++   Q +E+  Q +E   + +E+L   +
Sbjct: 1812 LAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSK 1871

Query: 496  EKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQ 555
            +++ + + K+    + + + EEK+ +++E + +++EK+ E E +L Q E+ + +++   +
Sbjct: 1872 KQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQ---E 1928

Query: 556  ELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELK 595
            +L +   KL  +  ++ G  R  G   +      L +E+K
Sbjct: 1929 KLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKALNLEMK 1968



 Score =  132 bits (333), Expect = 8e-31
 Identities = 123/568 (21%), Positives = 265/568 (46%), Gaps = 70/568 (12%)

Query: 131  VKSSFKKRQEKMNEKNYTFRKRVVIKK--PWLRLGEVTAQKRPENSLLEETLHFDHAVRM 188
            +  S  K  E +N +  TF + +++ +   W    E+    + E+ +L E L +D     
Sbjct: 1254 ISGSQTKMSENLNAELVTFAQEMLVDRHPSWELFQEICPLLKKESKVLLEDLDWD----- 1308

Query: 189  GTYIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKL 248
                       +   + +    I ++ ++    E+     ++  E+ + Q   +D+   L
Sbjct: 1309 -------VVPPEKKPIFIQEGAIREDMIQGVTQEVIRHKEVMPREEEQAQKKARDMLG-L 1360

Query: 249  ERAQLLLPQQQLQVEAD----RLGKELQSVSAKLQAQVEENELWNLLNQQQE-----EKM 299
            E  Q++L + +  +  +     +GKE+     K   Q    +    + ++++      +M
Sbjct: 1361 EETQVILKKGKKVIFLEPGNVTMGKEISKKEEKKTFQKSPKQGRKAVQKERKVGKIKREM 1420

Query: 300  WRQEEKIQEQEEKMCEQELKIREQEEKM--------WRQEEKMHEQEEKIREQEDKMWRQ 351
             ++E  + E+ E+M   E K+ +QE K+        W+  +K  ++ +++  +  K W+ 
Sbjct: 1421 TKEERDMSEEVEEMATLEEKVVKQEGKLVMIERTPSWQDWKKAWDEWKQVHGETRKSWKA 1480

Query: 352  -----EEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQ--EEKIREQEEKR 404
                 E+++ ++EEK+ +  EK+  +EE ++E  +   E+ +++W      K +EQ+ K 
Sbjct: 1481 WKEEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKD 1540

Query: 405  QEKMWRQEKKMREQDEKIRE--------QEEEMW--------RQEEKIRELEEMMQDQEE 448
            +E++  +E+  RE +EK ++        QEE  W        R E+K  + E  +  +EE
Sbjct: 1541 EEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEE 1600

Query: 449  KLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQE-EKIWEQEEKMWR 507
            KL + E ++ +EE K+ +   KI + + ++ + E K  ++E+ L Q  EK+ ++ EK+ +
Sbjct: 1601 KLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQ 1660

Query: 508  QEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKM---------QEQEV--RLQE 556
            + +K+ ++ EK+  +EEK+ ++  K+ E +  L Q+ E++         QE+E+   L+E
Sbjct: 1661 KRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEE 1720

Query: 557  LEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQQY 616
            LE  + +L  K E L    +E G           + E  + + + L +++       +  
Sbjct: 1721 LEWDMEELSWKEEEL---NQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELL 1777

Query: 617  VAAYQQLASGKEALPSCSSRKLRAKRWL 644
            +   ++LA  KE +P    R  R +  L
Sbjct: 1778 IQEKEKLAQHKEKMPEEEERLGRKREQL 1805



 Score =  115 bits (288), Expect = 1e-25
 Identities = 125/566 (22%), Positives = 272/566 (48%), Gaps = 63/566 (11%)

Query: 51   GKPREKSIADE--------KFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKES 102
            G+ +E+ + +E        K+ ++    A  E ++ +  ++  ++++    E+ +  +E 
Sbjct: 1554 GEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEE 1613

Query: 103  LKR----VTFTLPDDEAIEDAG---------VSHVKKNSDEVKSSFKKRQEKMNEKNYTF 149
             K     V  T  D E  +  G             +K S E +   +KR++   +     
Sbjct: 1614 RKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVA 1673

Query: 150  RKRVVIKKPWLRLGEVT---AQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDAPSLEL 206
            R+   + K   +L EV    AQK  E    E+ L +          ++L +E +    ++
Sbjct: 1674 REEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQE--------KELAQELEELEWDM 1725

Query: 207  YRNTITDEELKEKNAEL-QEKLRLVESEKS-----------EIQLNVKDLKRKLERAQLL 254
               +  +EEL ++  +L +EK +L E E++           E +L  ++     E+ +L 
Sbjct: 1726 EELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLA 1785

Query: 255  LPQQQLQVEADRLGKELQSVSAKLQAQVEENELW-NLLNQQQEEKMWRQEEKIQEQEEKM 313
              ++++  E +RLG++ + +  K     ++ E W N + +  + KM   ++K   QE+K 
Sbjct: 1786 QHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKN 1845

Query: 314  CEQEL-KIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQ 372
              QE  K+ +++E +   +E++   ++++ + ++K+    + + + EEK+ +++E + ++
Sbjct: 1846 LAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKK 1905

Query: 373  EEKIREQDEKIQEQEEEMWRQEEKIREQEEK-RQEKMWRQEKKMREQDEKIREQEE---- 427
            +EK+ E ++K+ + E+ + +++EK+ +++ K   EK   Q KK    +  I ++E+    
Sbjct: 1906 KEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKALNL 1965

Query: 428  EMWR-QEEKIRELE--EMMQDQEEKLREVEEKMQEEEEKMQEQ----EEKIQRQEEKIQE 480
            EM R  EEK+R +E  E +   E      + KM + E+++ E+    EEKI   E++I  
Sbjct: 1966 EMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKILLHEDRILA 2025

Query: 481  QEEKTWRQEKL-LKQEEKIWEQ-EEKMWRQEEKMWEQEEKMQEQEEKMQ---RQEEKMRE 535
             EE    + KL   + ++I+ Q + K+ +   K+ ++ E + ++  K+    +  +K+  
Sbjct: 2026 MEESEIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLNKILKALQKLTR 2085

Query: 536  QEVRLWQQEEKMQEQEVRLQELEERL 561
             E +L Q+E KM + +  L   E RL
Sbjct: 2086 DERKLTQEEIKMTKMKRALFVKERRL 2111



 Score =  107 bits (268), Expect = 3e-23
 Identities = 133/602 (22%), Positives = 290/602 (48%), Gaps = 101/602 (16%)

Query: 54   REKSIADEKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDD 113
            +++ +A EK      M+  LE    +G KR   + D+ + E  K     +KR+       
Sbjct: 1926 KQEKLAQEK------MKLALEKAMVQGKKRLRGELDIAKEE--KALNLEMKRL------- 1970

Query: 114  EAIEDAGVSHVKKNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPEN 173
             A E   +   K+   + ++    RQ KM +      +R +  +  + L E       E+
Sbjct: 1971 -AEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKILLHEDRILAMEES 2029

Query: 174  SLLEETLHFDHAVR--------MGTYIEKLTKERDAPSLELYRNTITDEELKEKNAELQE 225
             + +  L F    R        +     KL K+R++ S E  +    ++ LK      ++
Sbjct: 2030 EIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAK---LNKILKALQKLTRD 2086

Query: 226  KLRLVESE----KSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQ 281
            + +L + E    K +  L VK+ +  +E+++L + +     +   L K+ + ++ K +  
Sbjct: 2087 ERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQRKL 2146

Query: 282  VEENELWNLLNQQQEEKMWRQEEKIQEQEEKMC---EQELKIREQE-----EKMWRQEEK 333
               N++  ++N+  EEKM  +E K+  +  ++    E+E  I E+E     ++ WR+ ++
Sbjct: 2147 A--NKMRRMINK--EEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKE 2202

Query: 334  MH---EQEEKIREQEDKMWRQEEKIREQE---EKIREQEEKMWRQEEKIREQDEKIQEQE 387
                 + +EK   Q D++  +E    E E   +++ +QE     +EE+  E++E      
Sbjct: 2203 AKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEE------ 2256

Query: 388  EEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQE 447
                R+EE++RE+EE+R+E+   +EK++ +++E+ +++++E  +++E+++E EE+ +++E
Sbjct: 2257 ----REEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKE--KKKEEVQEKEEVFEEKE 2310

Query: 448  EKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEE--KIWEQEEKM 505
            E + E      EE E + ++EE     EE+    EE+  R++++LK+E+  K+ EQ  K 
Sbjct: 2311 EIMSE------EETESLSDEEE-----EEESCSLEEEVDREKEILKKEKQFKLQEQRRKS 2359

Query: 506  WRQEEKMWE-------------QEEKMQEQEEKMQRQEEKMREQ-EVRLWQQEEKMQEQE 551
             R  E++               +   ++   +K+     +M+E+  V + +++   ++++
Sbjct: 2360 LRGRERVLSILRGVPHGKGRAIRLGVLKSPLKKLMSTALEMKEKTPVPVPEKQISWEDKK 2419

Query: 552  VRLQELEER-LGKLGQKAELLG----------GAGRESGSQRL--PTLTPILQVELKSQE 598
              + E+  + LG + ++ E++G          G   ES +Q L  P ++ IL+  ++++E
Sbjct: 2420 ATVVEIPRKFLGTMDKEREVMGKYEPIPPHVLGTVLESQAQDLKTPFMSHILRRTVEAEE 2479

Query: 599  AQ 600
             Q
Sbjct: 2480 LQ 2481


>gi|194097392 Golgi autoantigen, golgin subfamily a, 2 [Homo
           sapiens]
          Length = 1002

 Score =  143 bits (361), Expect = 4e-34
 Identities = 125/491 (25%), Positives = 240/491 (48%), Gaps = 63/491 (12%)

Query: 191 YIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLER 250
           Y ++LTKERDA  LELY+NT ++E+LK++ +EL+EKLR++ +EK+ +QLN+++L++KLE 
Sbjct: 285 YNKELTKERDALRLELYKNTQSNEDLKQEKSELEEKLRVLVTEKAGMQLNLEELQKKLEM 344

Query: 251 AQLLLPQQQLQVEADRLGKEL-QSVSAKLQAQVEENELWNLLNQQQEEK----------- 298
            +LLL Q   + EA    ++L Q++  + Q +    ++   + Q Q E+           
Sbjct: 345 TELLLQQFSSRCEAPDANQQLQQAMEERAQLEAHLGQVMESVRQLQMERDKYAENLKGES 404

Query: 299 -MWRQE-EKIQEQ-----EEKMCE----QELKIREQEEKMWRQEEKMHEQEEKIREQEDK 347
            MWRQ  +++ EQ     EEK C     QEL+    E +    E    E      E E +
Sbjct: 405 AMWRQRMQQMSEQVHTLREEKECSMSRVQELETSLAELRNQMAEPPPPEPPAGPSEVEQQ 464

Query: 348 MWRQEEKIREQEEKIREQEEKMWRQEEKI----REQDEKIQEQEE--EMWRQEEKIREQ- 400
           +  + E +R++ E +  Q +   +  E +    REQ+E++ E E   E+W ++ + R Q 
Sbjct: 465 LQAEAEHLRKELEGLAGQLQAQVQDNEGLSRLNREQEERLLELERAAELWGEQAEARRQI 524

Query: 401 ---EEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKM 457
               +  +  + R   + RE  E++ E +    +   +  E+   +Q ++   RE+ +K+
Sbjct: 525 LETMQNDRTTISRALSQNRELKEQLAELQSGFVKLTNENMEITSALQSEQHVKRELGKKL 584

Query: 458 QEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEE 517
            E +EK+ E +E ++ + ++ Q  +++  +    L+Q    ++Q       E+++   + 
Sbjct: 585 GELQEKLSELKETVELKSQEAQSLQQQRDQYLGHLQQYVAAYQQ----LTSEKEVLHNQL 640

Query: 518 KMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRE 577
            +Q Q     +Q+E   +    + +QE  +QE + RL+   ++  +L  +  L+   G  
Sbjct: 641 LLQTQLVDQLQQQEAQGKAVAEMARQE--LQETQERLEAATQQNQQLRAQLSLMAHPGEG 698

Query: 578 SGSQR---------------LPTLTPILQVELKSQEAQ---------SLQQQQDHYRGHL 613
            G  R               +P   P +  +L+S+EA          S +++Q   RG L
Sbjct: 699 DGLDREEEEDEEEEEEEAVAVPQPMPSIPEDLESREAMVAFFNSAVASAEEEQARLRGQL 758

Query: 614 QQYVAAYQQLA 624
           ++     ++LA
Sbjct: 759 KEQRVRCRRLA 769



 Score =  118 bits (296), Expect = 2e-26
 Identities = 132/480 (27%), Positives = 225/480 (46%), Gaps = 85/480 (17%)

Query: 211 ITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKL------------ERAQLLLPQQ 258
           IT E+LK++N E+ ++L   E EK E       L+ +L            E+A+L     
Sbjct: 182 ITIEKLKQQNQEITDQL---EEEKKECHQKQGALREQLQVHIQTIGILVSEKAELQTALA 238

Query: 259 QLQVEADRLGKELQSVSAKLQ-AQVEENELWNLLN--QQQEEKMWRQEEKIQEQEEKMCE 315
             Q  A +   E + ++++LQ ++    EL   L+    Q++K  R  +++ ++ + +  
Sbjct: 239 HTQHAARQKEGESEDLASRLQYSRRRVGELERALSAVSTQQKKADRYNKELTKERDAL-R 297

Query: 316 QELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEK 375
            EL    Q  +  +QE+   E EEK+R    +    +  + E ++K+   E  + +   +
Sbjct: 298 LELYKNTQSNEDLKQEKS--ELEEKLRVLVTEKAGMQLNLEELQKKLEMTELLLQQFSSR 355

Query: 376 IREQD--EKIQEQEEEMWRQE-------EKIREQEEKR---------QEKMWRQE-KKMR 416
               D  +++Q+  EE  + E       E +R+ + +R         +  MWRQ  ++M 
Sbjct: 356 CEAPDANQQLQQAMEERAQLEAHLGQVMESVRQLQMERDKYAENLKGESAMWRQRMQQMS 415

Query: 417 EQDEKIREQEE-EMWRQEEKIRELEEMMQDQEEKL--------REVEEKMQEEEEKMQEQ 467
           EQ   +RE++E  M R +E    L E+     E           EVE+++Q E E ++++
Sbjct: 416 EQVHTLREEKECSMSRVQELETSLAELRNQMAEPPPPEPPAGPSEVEQQLQAEAEHLRKE 475

Query: 468 EEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEE--KMWRQEEKMWEQE-EKMQEQEE 524
            E +  Q +   +  E   R  +  +QEE++ E E   ++W ++ +   Q  E MQ    
Sbjct: 476 LEGLAGQLQAQVQDNEGLSRLNR--EQEERLLELERAAELWGEQAEARRQILETMQNDRT 533

Query: 525 KMQR---QEEKMREQEVRLWQQEEKMQEQEVRL-----------QELEERLGKLGQKAEL 570
            + R   Q  +++EQ   L     K+  + + +           +EL ++LG+L +K   
Sbjct: 534 TISRALSQNRELKEQLAELQSGFVKLTNENMEITSALQSEQHVKRELGKKLGELQEKLSE 593

Query: 571 LGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQQYVAAYQQLASGKEAL 630
           L    +E+             VELKSQEAQSLQQQ+D Y GHLQQYVAAYQQL S KE L
Sbjct: 594 L----KET-------------VELKSQEAQSLQQQRDQYLGHLQQYVAAYQQLTSEKEVL 636



 Score = 88.2 bits (217), Expect = 2e-17
 Identities = 110/558 (19%), Positives = 245/558 (43%), Gaps = 51/558 (9%)

Query: 74  ENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKS 133
           E  K R   R +   + + +ED KQ K  L+     L  ++A        ++ N +E++ 
Sbjct: 288 ELTKERDALRLELYKNTQSNEDLKQEKSELEEKLRVLVTEKA-------GMQLNLEELQK 340

Query: 134 SFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIE 193
             +  +             +++++   R     A ++ + ++ E      H  ++   + 
Sbjct: 341 KLEMTE-------------LLLQQFSSRCEAPDANQQLQQAMEERAQLEAHLGQVMESVR 387

Query: 194 KLTKERDAPSLELYRNTITDEEL--KEKNAELQEKLRLVESEKSEIQLNVKDLKRKLE-- 249
           +L  ERD      Y   +  E    +++  ++ E++  +  EK      V++L+  L   
Sbjct: 388 QLQMERDK-----YAENLKGESAMWRQRMQQMSEQVHTLREEKECSMSRVQELETSLAEL 442

Query: 250 RAQLLLP------------QQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEE 297
           R Q+  P            +QQLQ EA+ L KEL+ ++ +LQAQV++NE  + LN++QEE
Sbjct: 443 RNQMAEPPPPEPPAGPSEVEQQLQAEAEHLRKELEGLAGQLQAQVQDNEGLSRLNREQEE 502

Query: 298 KMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIRE 357
           ++  + E+  E   +  E   +I E  +       +   Q  +++EQ  ++     K+  
Sbjct: 503 RLL-ELERAAELWGEQAEARRQILETMQNDRTTISRALSQNRELKEQLAELQSGFVKLTN 561

Query: 358 QEEKIRE--QEEKMWRQE--EKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEK 413
           +  +I    Q E+  ++E  +K+ E  EK+ E +E +  + ++ +  +++R + +   ++
Sbjct: 562 ENMEITSALQSEQHVKRELGKKLGELQEKLSELKETVELKSQEAQSLQQQRDQYLGHLQQ 621

Query: 414 KMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQR 473
            +    +++  ++E +  Q     +L + +Q QE + + V E  ++E ++ QE+ E   +
Sbjct: 622 YVAAY-QQLTSEKEVLHNQLLLQTQLVDQLQQQEAQGKAVAEMARQELQETQERLEAATQ 680

Query: 474 QEEKIQEQEEKTWRQEKL----LKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQ 529
           Q ++++ Q        +      ++EE   E+EE+     + M    E ++ +E  +   
Sbjct: 681 QNQQLRAQLSLMAHPGEGDGLDREEEEDEEEEEEEAVAVPQPMPSIPEDLESREAMVAFF 740

Query: 530 EEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPI 589
              +   E    +   +++EQ VR + L   L    ++ E    A    G          
Sbjct: 741 NSAVASAEEEQARLRGQLKEQRVRCRRLAHLLASAQKEPEAAAPAPGTGGDSVCGETHRA 800

Query: 590 LQVELKSQEAQSLQQQQD 607
           LQ  ++  +++ ++  Q+
Sbjct: 801 LQGAMEKLQSRFMELMQE 818



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 58/304 (19%), Positives = 128/304 (42%), Gaps = 40/304 (13%)

Query: 215 ELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKEL--- 271
           EL+EK +EL+E + L   E   +Q         L+  Q +   QQL  E + L  +L   
Sbjct: 586 ELQEKLSELKETVELKSQEAQSLQQQRDQYLGHLQ--QYVAAYQQLTSEKEVLHNQLLLQ 643

Query: 272 -QSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQE-EKMWR 329
            Q V    Q + +   +  +  Q+ +E   R E   Q+ ++   +  L     E + + R
Sbjct: 644 TQLVDQLQQQEAQGKAVAEMARQELQETQERLEAATQQNQQLRAQLSLMAHPGEGDGLDR 703

Query: 330 QEEKMHEQEEK--------IREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDE 381
           +EE+  E+EE+        +    + +  +E  +      +   EE+  R   +++EQ  
Sbjct: 704 EEEEDEEEEEEEAVAVPQPMPSIPEDLESREAMVAFFNSAVASAEEEQARLRGQLKEQRV 763

Query: 382 KIQE--------QEE-----------------EMWRQEEKIREQEEKRQEKMWRQEKKMR 416
           + +         Q+E                 E  R  +   E+ + R  ++ +++  ++
Sbjct: 764 RCRRLAHLLASAQKEPEAAAPAPGTGGDSVCGETHRALQGAMEKLQSRFMELMQEKADLK 823

Query: 417 EQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEE 476
           E+ E++  +  ++  + + I E   + Q Q   L+E   + +E   ++ + +E+++ +  
Sbjct: 824 ERVEELEHRCIQLSGETDTIGEYIALYQSQRAVLKERHREKEEYISRLAQDKEEMKVKLL 883

Query: 477 KIQE 480
           ++QE
Sbjct: 884 ELQE 887



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 70/418 (16%), Positives = 174/418 (41%), Gaps = 52/418 (12%)

Query: 68  EMEAYLENRKRRGTKRWDEDDDLEESEDSKQC----KESLKRVTFTLPDDEAIEDAGVSH 123
           +++A +++ +       ++++ L E E + +      E+ +++  T+ +D       +S 
Sbjct: 482 QLQAQVQDNEGLSRLNREQEERLLELERAAELWGEQAEARRQILETMQNDRTTISRALSQ 541

Query: 124 ---VKKNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETL 180
              +K+   E++S F K   +  E     +    +K+    LG+   + + + S L+ET+
Sbjct: 542 NRELKEQLAELQSGFVKLTNENMEITSALQSEQHVKR---ELGKKLGELQEKLSELKETV 598

Query: 181 HFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLN 240
                       + L ++RD     L +     ++L  +   L  +L L      ++Q  
Sbjct: 599 ELK-----SQEAQSLQQQRDQYLGHLQQYVAAYQQLTSEKEVLHNQLLLQTQLVDQLQQQ 653

Query: 241 VKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMW 300
               K   E A+  L + Q ++EA    ++ Q + A+L       E   L  +++E++  
Sbjct: 654 EAQGKAVAEMARQELQETQERLEAAT--QQNQQLRAQLSLMAHPGEGDGLDREEEEDEEE 711

Query: 301 RQEEKIQ-EQEEKMCEQELKIREQ------------EEKMWRQEEKMHEQEEKIREQEDK 347
            +EE +   Q      ++L+ RE             EE+  R   ++ EQ  + R     
Sbjct: 712 EEEEAVAVPQPMPSIPEDLESREAMVAFFNSAVASAEEEQARLRGQLKEQRVRCRRLAHL 771

Query: 348 MWRQEEK----------------------IREQEEKIREQEEKMWRQEEKIREQDEKIQE 385
           +   +++                      ++   EK++ +  ++ +++  ++E+ E+++ 
Sbjct: 772 LASAQKEPEAAAPAPGTGGDSVCGETHRALQGAMEKLQSRFMELMQEKADLKERVEELEH 831

Query: 386 QEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMM 443
           +  ++  + + I E     Q +    +++ RE++E I    ++    + K+ EL+E++
Sbjct: 832 RCIQLSGETDTIGEYIALYQSQRAVLKERHREKEEYISRLAQDKEEMKVKLLELQELV 889


>gi|169210281 PREDICTED: similar to M-phase phosphoprotein 10 (U3
           small nucleolar ribonucleoprotein) [Homo sapiens]
          Length = 213

 Score =  140 bits (352), Expect = 5e-33
 Identities = 79/143 (55%), Positives = 99/143 (69%), Gaps = 9/143 (6%)

Query: 1   MGGDNPEVSERA-NSSKFDPTKSPVLSDEDSDLDFHINKLEQQSKVRNKGHGKPREKSIA 59
           MGGDNPEV ++A NSSKF+  KSPV SDEDSDLDF I+KLEQQSKV+N GHGKPREKSI 
Sbjct: 63  MGGDNPEVGKKARNSSKFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSII 122

Query: 60  DEKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDA 119
           DEKFFQLSEMEAYLENR++   ++ D DD+  +S  +   K+    V       E+ ED 
Sbjct: 123 DEKFFQLSEMEAYLENREKEEERKDDNDDESGKSSRNVNNKDFFDPV-------ESDEDI 175

Query: 120 GVSHVKK-NSDEVKSSFKKRQEK 141
              H  +  S+++    KK+Q+K
Sbjct: 176 ASDHDDELGSNKMMKLLKKKQKK 198



 Score = 35.8 bits (81), Expect = 0.13
 Identities = 34/137 (24%), Positives = 61/137 (44%), Gaps = 6/137 (4%)

Query: 430 WRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQE 489
           W+  E   E EE  Q+ EE   E E   QE+ E +QE+EE      +   E  +K     
Sbjct: 22  WQIVELGEESEE--QECEEDGSETETGGQEDLEDLQEEEEVSDMGGDN-PEVGKKARNSS 78

Query: 490 KLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQE---EK 546
           K   ++  ++  E+     +    EQ+ K+Q       R++  + E+  +L + E   E 
Sbjct: 79  KFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLEN 138

Query: 547 MQEQEVRLQELEERLGK 563
            +++E R  + ++  GK
Sbjct: 139 REKEEERKDDNDDESGK 155


>gi|169210488 PREDICTED: similar to M-phase phosphoprotein 10 (U3
           small nucleolar ribonucleoprotein) [Homo sapiens]
          Length = 213

 Score =  140 bits (352), Expect = 5e-33
 Identities = 79/143 (55%), Positives = 99/143 (69%), Gaps = 9/143 (6%)

Query: 1   MGGDNPEVSERA-NSSKFDPTKSPVLSDEDSDLDFHINKLEQQSKVRNKGHGKPREKSIA 59
           MGGDNPEV ++A NSSKF+  KSPV SDEDSDLDF I+KLEQQSKV+N GHGKPREKSI 
Sbjct: 63  MGGDNPEVGKKARNSSKFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSII 122

Query: 60  DEKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDA 119
           DEKFFQLSEMEAYLENR++   ++ D DD+  +S  +   K+    V       E+ ED 
Sbjct: 123 DEKFFQLSEMEAYLENREKEEERKDDNDDESVKSSRNVNNKDFFDPV-------ESDEDI 175

Query: 120 GVSHVKK-NSDEVKSSFKKRQEK 141
              H  +  S+++    KK+Q+K
Sbjct: 176 ASDHDDELGSNKMMKLLKKKQKK 198



 Score = 33.5 bits (75), Expect = 0.64
 Identities = 30/122 (24%), Positives = 54/122 (44%), Gaps = 3/122 (2%)

Query: 430 WRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQE 489
           W+  E   E EE  Q+ EE   E E   QE+ E +QE+EE      +   E  +K     
Sbjct: 22  WQIVELGEESEE--QECEEDGSETETGGQEDLEDLQEEEEVSDMGGDN-PEVGKKARNSS 78

Query: 490 KLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQE 549
           K   ++  ++  E+     +    EQ+ K+Q       R++  + E+  +L + E  ++ 
Sbjct: 79  KFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLEN 138

Query: 550 QE 551
           +E
Sbjct: 139 RE 140


>gi|169210051 PREDICTED: similar to M-phase phosphoprotein 10 (U3
           small nucleolar ribonucleoprotein) [Homo sapiens]
          Length = 213

 Score =  140 bits (352), Expect = 5e-33
 Identities = 79/143 (55%), Positives = 99/143 (69%), Gaps = 9/143 (6%)

Query: 1   MGGDNPEVSERA-NSSKFDPTKSPVLSDEDSDLDFHINKLEQQSKVRNKGHGKPREKSIA 59
           MGGDNPEV ++A NSSKF+  KSPV SDEDSDLDF I+KLEQQSKV+N GHGKPREKSI 
Sbjct: 63  MGGDNPEVGKKARNSSKFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSII 122

Query: 60  DEKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDA 119
           DEKFFQLSEMEAYLENR++   ++ D DD+  +S  +   K+    V       E+ ED 
Sbjct: 123 DEKFFQLSEMEAYLENREKEEERKDDNDDESGKSSRNVNNKDFFDPV-------ESDEDI 175

Query: 120 GVSHVKK-NSDEVKSSFKKRQEK 141
              H  +  S+++    KK+Q+K
Sbjct: 176 ASDHDDELGSNKMMKLLKKKQKK 198



 Score = 35.8 bits (81), Expect = 0.13
 Identities = 34/137 (24%), Positives = 61/137 (44%), Gaps = 6/137 (4%)

Query: 430 WRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQE 489
           W+  E   E EE  Q+ EE   E E   QE+ E +QE+EE      +   E  +K     
Sbjct: 22  WQIVELGEESEE--QECEEDGSETETGGQEDLEDLQEEEEVSDMGGDN-PEVGKKARNSS 78

Query: 490 KLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQE---EK 546
           K   ++  ++  E+     +    EQ+ K+Q       R++  + E+  +L + E   E 
Sbjct: 79  KFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLEN 138

Query: 547 MQEQEVRLQELEERLGK 563
            +++E R  + ++  GK
Sbjct: 139 REKEEERKDDNDDESGK 155


>gi|169208458 PREDICTED: similar to golgi autoantigen, golgin
           subfamily a-like [Homo sapiens]
          Length = 432

 Score =  139 bits (350), Expect = 8e-33
 Identities = 87/237 (36%), Positives = 150/237 (63%), Gaps = 30/237 (12%)

Query: 231 ESEKSEIQLNVKDLKRKL-----ERAQLLLPQ--------QQLQVEADRLGKELQSVSAK 277
           E +K EI L V+ L R L     + A+ L PQ        +QLQ E + L KEL+SV  +
Sbjct: 121 EEKKHEIHL-VQKLGRSLFKLKNQTAEPLAPQPPAGPSKVEQLQDETNHLRKELESVGRQ 179

Query: 278 LQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQ 337
           LQA+VE N++ +LLN++QEE++  QEE+++EQEE++CEQE ++ EQEE++  QEE++ EQ
Sbjct: 180 LQAEVENNQMLSLLNRRQEERLREQEERLREQEERLCEQEERLCEQEERLREQEERLCEQ 239

Query: 338 E-----EKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWR 392
           E     E++ E+ +K+ +QE +  EQE  +  + E++  + E++ EQ E++++Q+E +W+
Sbjct: 240 EKLPGQERLLEEVEKLLKQERRQEEQERLL--ERERLLDEVEELLEQ-ERLRQQDERLWQ 296

Query: 393 QE-----EKIREQE---EKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEE 441
           QE     E++RE E   E   E ++ Q  + R   E++  + +   + E++++ELE+
Sbjct: 297 QETLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELEK 353



 Score =  108 bits (270), Expect = 2e-23
 Identities = 78/266 (29%), Positives = 145/266 (54%), Gaps = 19/266 (7%)

Query: 330 QEEKMHEQEEKIREQEDKMWRQEEKIREQE-EKIREQEEKMWRQEEKIREQDEKIQEQEE 388
           +EEK HE          K+ R   K++ Q  E +  Q      + E+++++   ++++ E
Sbjct: 120 KEEKKHEIH-----LVQKLGRSLFKLKNQTAEPLAPQPPAGPSKVEQLQDETNHLRKELE 174

Query: 389 EMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEE 448
            + RQ +   E  +       RQE+++REQ+E++REQEE +  QEE++ E EE +++QEE
Sbjct: 175 SVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLCEQEERLCEQEERLREQEE 234

Query: 449 KLREVE-----EKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEE 503
           +L E E     E++ EE EK+ +QE + Q ++E++ E+E      E+LL+Q E++ +Q+E
Sbjct: 235 RLCEQEKLPGQERLLEEVEKLLKQERR-QEEQERLLERERLLDEVEELLEQ-ERLRQQDE 292

Query: 504 KMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGK 563
           ++W+QE     + E+++E E  ++   E + EQ        E++  +     +LE+++ +
Sbjct: 293 RLWQQE--TLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKE 350

Query: 564 LGQKAELLGGAGRESGSQRLPTLTPI 589
           L    E  GGA    GS+      P+
Sbjct: 351 L----EKSGGAEEPRGSESAAAARPV 372



 Score = 90.1 bits (222), Expect = 6e-18
 Identities = 66/231 (28%), Positives = 126/231 (54%), Gaps = 32/231 (13%)

Query: 382 KIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQD------------EKIREQEEEM 429
           ++ E    + R  ++ ++ E    +K+ R   K++ Q              K+ + ++E 
Sbjct: 107 QLTENINSLVRTSKEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPQPPAGPSKVEQLQDET 166

Query: 430 WRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQ- 488
               +++  +   +Q + E  + +    + +EE+++EQEE+++ QEE++ EQEE+   Q 
Sbjct: 167 NHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLCEQEERLCEQE 226

Query: 489 EKLLKQEEKIWEQE-----EKMWRQEEKMWEQEEKMQEQEEKMQR-----------QEEK 532
           E+L +QEE++ EQE     E++  + EK+ +QE + +EQE  ++R           ++E+
Sbjct: 227 ERLREQEERLCEQEKLPGQERLLEEVEKLLKQERRQEEQERLLERERLLDEVEELLEQER 286

Query: 533 MREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRL 583
           +R+Q+ RLWQQ E ++E E RL+EL ER+ +LG +A     A   SG + L
Sbjct: 287 LRQQDERLWQQ-ETLRELE-RLREL-ERMLELGWEALYEQRAEPRSGFEEL 334



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 46/184 (25%), Positives = 93/184 (50%), Gaps = 22/184 (11%)

Query: 193 EKLTKERDAPSLELYRNTITDEELKEKNAELQEKL-RLVESEKSEIQLNVKDLKRKLERA 251
           E+L ++ +    +  R    +E L E+   L+E+  RL E EK   Q      +R LE  
Sbjct: 199 ERLREQEERLREQEERLCEQEERLCEQEERLREQEERLCEQEKLPGQ------ERLLEEV 252

Query: 252 QLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEE 311
           + LL Q++ Q E +RL  E + +  +++  +E+  L     +QQ+E++W Q+E ++E E 
Sbjct: 253 EKLLKQERRQEEQERL-LERERLLDEVEELLEQERL-----RQQDERLW-QQETLRELE- 304

Query: 312 KMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWR 371
                  ++RE E  +    E ++EQ  + R   +++  + +   + E++++E E+    
Sbjct: 305 -------RLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELEKSGGA 357

Query: 372 QEEK 375
           +E +
Sbjct: 358 EEPR 361


>gi|154937324 hypothetical protein LOC440295 [Homo sapiens]
          Length = 432

 Score =  139 bits (350), Expect = 8e-33
 Identities = 87/237 (36%), Positives = 150/237 (63%), Gaps = 30/237 (12%)

Query: 231 ESEKSEIQLNVKDLKRKL-----ERAQLLLPQ--------QQLQVEADRLGKELQSVSAK 277
           E +K EI L V+ L R L     + A+ L PQ        +QLQ E + L KEL+SV  +
Sbjct: 121 EEKKHEIHL-VQKLGRSLFKLKNQTAEPLAPQPPAGPSKVEQLQDETNHLRKELESVGRQ 179

Query: 278 LQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQ 337
           LQA+VE N++ +LLN++QEE++  QEE+++EQEE++CEQE ++ EQEE++  QEE++ EQ
Sbjct: 180 LQAEVENNQMLSLLNRRQEERLREQEERLREQEERLCEQEERLCEQEERLREQEERLCEQ 239

Query: 338 E-----EKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWR 392
           E     E++ E+ +K+ +QE +  EQE  +  + E++  + E++ EQ E++++Q+E +W+
Sbjct: 240 EKLPGQERLLEEVEKLLKQERRQEEQERLL--ERERLLDEVEELLEQ-ERLRQQDERLWQ 296

Query: 393 QE-----EKIREQE---EKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEE 441
           QE     E++RE E   E   E ++ Q  + R   E++  + +   + E++++ELE+
Sbjct: 297 QETLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELEK 353



 Score =  108 bits (270), Expect = 2e-23
 Identities = 78/266 (29%), Positives = 145/266 (54%), Gaps = 19/266 (7%)

Query: 330 QEEKMHEQEEKIREQEDKMWRQEEKIREQE-EKIREQEEKMWRQEEKIREQDEKIQEQEE 388
           +EEK HE          K+ R   K++ Q  E +  Q      + E+++++   ++++ E
Sbjct: 120 KEEKKHEIH-----LVQKLGRSLFKLKNQTAEPLAPQPPAGPSKVEQLQDETNHLRKELE 174

Query: 389 EMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEE 448
            + RQ +   E  +       RQE+++REQ+E++REQEE +  QEE++ E EE +++QEE
Sbjct: 175 SVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLCEQEERLCEQEERLREQEE 234

Query: 449 KLREVE-----EKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEE 503
           +L E E     E++ EE EK+ +QE + Q ++E++ E+E      E+LL+Q E++ +Q+E
Sbjct: 235 RLCEQEKLPGQERLLEEVEKLLKQERR-QEEQERLLERERLLDEVEELLEQ-ERLRQQDE 292

Query: 504 KMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGK 563
           ++W+QE     + E+++E E  ++   E + EQ        E++  +     +LE+++ +
Sbjct: 293 RLWQQE--TLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKE 350

Query: 564 LGQKAELLGGAGRESGSQRLPTLTPI 589
           L    E  GGA    GS+      P+
Sbjct: 351 L----EKSGGAEEPRGSESAAAARPV 372



 Score = 90.1 bits (222), Expect = 6e-18
 Identities = 66/231 (28%), Positives = 126/231 (54%), Gaps = 32/231 (13%)

Query: 382 KIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQD------------EKIREQEEEM 429
           ++ E    + R  ++ ++ E    +K+ R   K++ Q              K+ + ++E 
Sbjct: 107 QLTENINSLVRTSKEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPQPPAGPSKVEQLQDET 166

Query: 430 WRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQ- 488
               +++  +   +Q + E  + +    + +EE+++EQEE+++ QEE++ EQEE+   Q 
Sbjct: 167 NHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLCEQEERLCEQE 226

Query: 489 EKLLKQEEKIWEQE-----EKMWRQEEKMWEQEEKMQEQEEKMQR-----------QEEK 532
           E+L +QEE++ EQE     E++  + EK+ +QE + +EQE  ++R           ++E+
Sbjct: 227 ERLREQEERLCEQEKLPGQERLLEEVEKLLKQERRQEEQERLLERERLLDEVEELLEQER 286

Query: 533 MREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRL 583
           +R+Q+ RLWQQ E ++E E RL+EL ER+ +LG +A     A   SG + L
Sbjct: 287 LRQQDERLWQQ-ETLRELE-RLREL-ERMLELGWEALYEQRAEPRSGFEEL 334



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 46/184 (25%), Positives = 93/184 (50%), Gaps = 22/184 (11%)

Query: 193 EKLTKERDAPSLELYRNTITDEELKEKNAELQEKL-RLVESEKSEIQLNVKDLKRKLERA 251
           E+L ++ +    +  R    +E L E+   L+E+  RL E EK   Q      +R LE  
Sbjct: 199 ERLREQEERLREQEERLCEQEERLCEQEERLREQEERLCEQEKLPGQ------ERLLEEV 252

Query: 252 QLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEE 311
           + LL Q++ Q E +RL  E + +  +++  +E+  L     +QQ+E++W Q+E ++E E 
Sbjct: 253 EKLLKQERRQEEQERL-LERERLLDEVEELLEQERL-----RQQDERLW-QQETLRELE- 304

Query: 312 KMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWR 371
                  ++RE E  +    E ++EQ  + R   +++  + +   + E++++E E+    
Sbjct: 305 -------RLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELEKSGGA 357

Query: 372 QEEK 375
           +E +
Sbjct: 358 EEPR 361


>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sapiens]
          Length = 1293

 Score =  134 bits (337), Expect = 3e-31
 Identities = 111/455 (24%), Positives = 231/455 (50%), Gaps = 70/455 (15%)

Query: 193  EKLTKERDAPSL--------------ELYRNTITDEELKEKNAELQEKLRLVESEKSEIQ 238
            E+LT++++  +L              + Y   +  ++    +++ Q++L L+  +   ++
Sbjct: 602  ERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTLK 661

Query: 239  LNVKDLKRKLERAQLLLPQQQLQVEADRLGK--ELQSVSAKLQAQVEENELWNLL----- 291
            + + D        Q ++P     V     G   ELQ  +++     E   +W+L      
Sbjct: 662  MRISD--------QNIIPSVTRSVSVPDTGSIWELQPTASQPTVW-EGGSVWDLPLDTTT 712

Query: 292  -NQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQ--EDKM 348
                 E+    ++ K  + E++  E E++ + +EE+  RQEE   +QEE +R Q  E++ 
Sbjct: 713  PGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERK 772

Query: 349  WRQEEKI--REQEEKIREQEEKMWRQEEKIREQ--DEKIQEQEEEMWRQEEKIREQEEKR 404
             R+EE++  R+QEE +R Q E    QE  +R Q  +E+ Q+QEE + R EE+ RE+EE+ 
Sbjct: 773  RREEEELARRKQEEALRRQRE----QEIALRRQREEEERQQQEEALRRLEERRREEEER- 827

Query: 405  QEKMWRQEKKMREQDEKIREQEEE--MWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462
                       R+Q+E +R+QEEE   W +EE+  E +  +++   ++ E   +++ EEE
Sbjct: 828  -----------RKQEELLRKQEEEAAKWAREEE--EAQRRLEENRLRMEEEAARLRHEEE 874

Query: 463  KMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEK---M 519
            + + +E ++QRQ+E +++++++     +L +Q+++  +Q  +M       W Q+      
Sbjct: 875  ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQ--QQLAQMKLPSSSTWGQQSNTTAC 932

Query: 520  QEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESG 579
            Q Q      + +K+ E+  R  ++E++ Q++E+ ++ L+++  +  QK    G   + SG
Sbjct: 933  QSQATLSLAEIQKLEEERERQLREEQRRQQREL-MKALQQQQQQQQQKLSGWGNVSKPSG 991

Query: 580  SQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQ 614
            + +         +E++ +EA+ +Q+QQ   + H Q
Sbjct: 992  TTK-------SLLEIQQEEARQMQKQQQQQQQHQQ 1019



 Score =  110 bits (275), Expect = 4e-24
 Identities = 82/258 (31%), Positives = 146/258 (56%), Gaps = 20/258 (7%)

Query: 378 EQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIR 437
           +Q EK +  + E  R+E ++R + E+ + K  RQE+  R+Q+E +R Q+EE    E K R
Sbjct: 721 QQLEKAKAAKLEQERREAEMRAKREEEERK--RQEELRRQQEEILRRQQEE----ERKRR 774

Query: 438 ELEEMMQ-DQEEKLR-----EVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKL 491
           E EE+ +  QEE LR     E+  + Q EEE+ Q+QEE ++R EE+ +E+EE+  ++E L
Sbjct: 775 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 834

Query: 492 LKQEEKI--W--EQEEKMWRQEE---KMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQE 544
            KQEE+   W  E+EE   R EE   +M E+  +++ +EE+ +R+E +++ Q+  L +Q 
Sbjct: 835 RKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQK-ELMRQR 893

Query: 545 EKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQ 604
           ++ QE   RLQ+ +++      K       G++S +    +   +   E++  E +  +Q
Sbjct: 894 QQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQ 953

Query: 605 QQDHYRGHLQQYVAAYQQ 622
            ++  R   ++ + A QQ
Sbjct: 954 LREEQRRQQRELMKALQQ 971



 Score = 97.4 bits (241), Expect = 4e-20
 Identities = 72/245 (29%), Positives = 133/245 (54%), Gaps = 22/245 (8%)

Query: 395 EKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMM---QDQEEKLR 451
           E++++ E+ +  K+   E++ RE + + + +EEE  RQEE  R+ EE++   Q++E K R
Sbjct: 718 EQLQQLEKAKAAKL---EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 774

Query: 452 EVEE---KMQEEEEKMQEQEE---KIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKM 505
           E EE   + QEE  + Q ++E   + QR+EE+ Q+QEE   R E+  ++EE+  +QEE +
Sbjct: 775 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 834

Query: 506 WRQEEK--MWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGK 563
            +QEE+   W +EE  +E + +++    +M E+  RL  +EE+ + +E+ +Q  +E + +
Sbjct: 835 RKQEEEAAKWAREE--EEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQ 892

Query: 564 LGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQQYVAAYQQL 623
             Q+ E L    ++   Q+L       Q++L S      Q      +      +A  Q+L
Sbjct: 893 RQQQQEALRRLQQQQQQQQL------AQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKL 946

Query: 624 ASGKE 628
              +E
Sbjct: 947 EEERE 951


>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sapiens]
          Length = 1320

 Score =  134 bits (337), Expect = 3e-31
 Identities = 111/455 (24%), Positives = 231/455 (50%), Gaps = 70/455 (15%)

Query: 193  EKLTKERDAPSL--------------ELYRNTITDEELKEKNAELQEKLRLVESEKSEIQ 238
            E+LT++++  +L              + Y   +  ++    +++ Q++L L+  +   ++
Sbjct: 629  ERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTLK 688

Query: 239  LNVKDLKRKLERAQLLLPQQQLQVEADRLGK--ELQSVSAKLQAQVEENELWNLL----- 291
            + + D        Q ++P     V     G   ELQ  +++     E   +W+L      
Sbjct: 689  MRISD--------QNIIPSVTRSVSVPDTGSIWELQPTASQPTVW-EGGSVWDLPLDTTT 739

Query: 292  -NQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQ--EDKM 348
                 E+    ++ K  + E++  E E++ + +EE+  RQEE   +QEE +R Q  E++ 
Sbjct: 740  PGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERK 799

Query: 349  WRQEEKI--REQEEKIREQEEKMWRQEEKIREQ--DEKIQEQEEEMWRQEEKIREQEEKR 404
             R+EE++  R+QEE +R Q E    QE  +R Q  +E+ Q+QEE + R EE+ RE+EE+ 
Sbjct: 800  RREEEELARRKQEEALRRQRE----QEIALRRQREEEERQQQEEALRRLEERRREEEER- 854

Query: 405  QEKMWRQEKKMREQDEKIREQEEE--MWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462
                       R+Q+E +R+QEEE   W +EE+  E +  +++   ++ E   +++ EEE
Sbjct: 855  -----------RKQEELLRKQEEEAAKWAREEE--EAQRRLEENRLRMEEEAARLRHEEE 901

Query: 463  KMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEK---M 519
            + + +E ++QRQ+E +++++++     +L +Q+++  +Q  +M       W Q+      
Sbjct: 902  ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQ--QQLAQMKLPSSSTWGQQSNTTAC 959

Query: 520  QEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESG 579
            Q Q      + +K+ E+  R  ++E++ Q++E+ ++ L+++  +  QK    G   + SG
Sbjct: 960  QSQATLSLAEIQKLEEERERQLREEQRRQQREL-MKALQQQQQQQQQKLSGWGNVSKPSG 1018

Query: 580  SQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQ 614
            + +         +E++ +EA+ +Q+QQ   + H Q
Sbjct: 1019 TTK-------SLLEIQQEEARQMQKQQQQQQQHQQ 1046



 Score =  110 bits (275), Expect = 4e-24
 Identities = 82/258 (31%), Positives = 146/258 (56%), Gaps = 20/258 (7%)

Query: 378 EQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIR 437
           +Q EK +  + E  R+E ++R + E+ + K  RQE+  R+Q+E +R Q+EE    E K R
Sbjct: 748 QQLEKAKAAKLEQERREAEMRAKREEEERK--RQEELRRQQEEILRRQQEE----ERKRR 801

Query: 438 ELEEMMQ-DQEEKLR-----EVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKL 491
           E EE+ +  QEE LR     E+  + Q EEE+ Q+QEE ++R EE+ +E+EE+  ++E L
Sbjct: 802 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 861

Query: 492 LKQEEKI--W--EQEEKMWRQEE---KMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQE 544
            KQEE+   W  E+EE   R EE   +M E+  +++ +EE+ +R+E +++ Q+  L +Q 
Sbjct: 862 RKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQK-ELMRQR 920

Query: 545 EKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQ 604
           ++ QE   RLQ+ +++      K       G++S +    +   +   E++  E +  +Q
Sbjct: 921 QQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQ 980

Query: 605 QQDHYRGHLQQYVAAYQQ 622
            ++  R   ++ + A QQ
Sbjct: 981 LREEQRRQQRELMKALQQ 998



 Score = 97.4 bits (241), Expect = 4e-20
 Identities = 72/245 (29%), Positives = 133/245 (54%), Gaps = 22/245 (8%)

Query: 395 EKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMM---QDQEEKLR 451
           E++++ E+ +  K+   E++ RE + + + +EEE  RQEE  R+ EE++   Q++E K R
Sbjct: 745 EQLQQLEKAKAAKL---EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 801

Query: 452 EVEE---KMQEEEEKMQEQEE---KIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKM 505
           E EE   + QEE  + Q ++E   + QR+EE+ Q+QEE   R E+  ++EE+  +QEE +
Sbjct: 802 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 861

Query: 506 WRQEEK--MWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGK 563
            +QEE+   W +EE  +E + +++    +M E+  RL  +EE+ + +E+ +Q  +E + +
Sbjct: 862 RKQEEEAAKWAREE--EEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQ 919

Query: 564 LGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQQYVAAYQQL 623
             Q+ E L    ++   Q+L       Q++L S      Q      +      +A  Q+L
Sbjct: 920 RQQQQEALRRLQQQQQQQQL------AQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKL 973

Query: 624 ASGKE 628
              +E
Sbjct: 974 EEERE 978


>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sapiens]
          Length = 1299

 Score =  134 bits (337), Expect = 3e-31
 Identities = 111/455 (24%), Positives = 231/455 (50%), Gaps = 70/455 (15%)

Query: 193  EKLTKERDAPSL--------------ELYRNTITDEELKEKNAELQEKLRLVESEKSEIQ 238
            E+LT++++  +L              + Y   +  ++    +++ Q++L L+  +   ++
Sbjct: 608  ERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTLK 667

Query: 239  LNVKDLKRKLERAQLLLPQQQLQVEADRLGK--ELQSVSAKLQAQVEENELWNLL----- 291
            + + D        Q ++P     V     G   ELQ  +++     E   +W+L      
Sbjct: 668  MRISD--------QNIIPSVTRSVSVPDTGSIWELQPTASQPTVW-EGGSVWDLPLDTTT 718

Query: 292  -NQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQ--EDKM 348
                 E+    ++ K  + E++  E E++ + +EE+  RQEE   +QEE +R Q  E++ 
Sbjct: 719  PGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERK 778

Query: 349  WRQEEKI--REQEEKIREQEEKMWRQEEKIREQ--DEKIQEQEEEMWRQEEKIREQEEKR 404
             R+EE++  R+QEE +R Q E    QE  +R Q  +E+ Q+QEE + R EE+ RE+EE+ 
Sbjct: 779  RREEEELARRKQEEALRRQRE----QEIALRRQREEEERQQQEEALRRLEERRREEEER- 833

Query: 405  QEKMWRQEKKMREQDEKIREQEEE--MWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462
                       R+Q+E +R+QEEE   W +EE+  E +  +++   ++ E   +++ EEE
Sbjct: 834  -----------RKQEELLRKQEEEAAKWAREEE--EAQRRLEENRLRMEEEAARLRHEEE 880

Query: 463  KMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEK---M 519
            + + +E ++QRQ+E +++++++     +L +Q+++  +Q  +M       W Q+      
Sbjct: 881  ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQ--QQLAQMKLPSSSTWGQQSNTTAC 938

Query: 520  QEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESG 579
            Q Q      + +K+ E+  R  ++E++ Q++E+ ++ L+++  +  QK    G   + SG
Sbjct: 939  QSQATLSLAEIQKLEEERERQLREEQRRQQREL-MKALQQQQQQQQQKLSGWGNVSKPSG 997

Query: 580  SQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQ 614
            + +         +E++ +EA+ +Q+QQ   + H Q
Sbjct: 998  TTK-------SLLEIQQEEARQMQKQQQQQQQHQQ 1025



 Score =  110 bits (275), Expect = 4e-24
 Identities = 82/258 (31%), Positives = 146/258 (56%), Gaps = 20/258 (7%)

Query: 378 EQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIR 437
           +Q EK +  + E  R+E ++R + E+ + K  RQE+  R+Q+E +R Q+EE    E K R
Sbjct: 727 QQLEKAKAAKLEQERREAEMRAKREEEERK--RQEELRRQQEEILRRQQEE----ERKRR 780

Query: 438 ELEEMMQ-DQEEKLR-----EVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKL 491
           E EE+ +  QEE LR     E+  + Q EEE+ Q+QEE ++R EE+ +E+EE+  ++E L
Sbjct: 781 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 840

Query: 492 LKQEEKI--W--EQEEKMWRQEE---KMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQE 544
            KQEE+   W  E+EE   R EE   +M E+  +++ +EE+ +R+E +++ Q+  L +Q 
Sbjct: 841 RKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQK-ELMRQR 899

Query: 545 EKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQ 604
           ++ QE   RLQ+ +++      K       G++S +    +   +   E++  E +  +Q
Sbjct: 900 QQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQ 959

Query: 605 QQDHYRGHLQQYVAAYQQ 622
            ++  R   ++ + A QQ
Sbjct: 960 LREEQRRQQRELMKALQQ 977



 Score = 97.4 bits (241), Expect = 4e-20
 Identities = 72/245 (29%), Positives = 133/245 (54%), Gaps = 22/245 (8%)

Query: 395 EKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMM---QDQEEKLR 451
           E++++ E+ +  K+   E++ RE + + + +EEE  RQEE  R+ EE++   Q++E K R
Sbjct: 724 EQLQQLEKAKAAKL---EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 780

Query: 452 EVEE---KMQEEEEKMQEQEE---KIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKM 505
           E EE   + QEE  + Q ++E   + QR+EE+ Q+QEE   R E+  ++EE+  +QEE +
Sbjct: 781 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 840

Query: 506 WRQEEK--MWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGK 563
            +QEE+   W +EE  +E + +++    +M E+  RL  +EE+ + +E+ +Q  +E + +
Sbjct: 841 RKQEEEAAKWAREE--EEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQ 898

Query: 564 LGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQQYVAAYQQL 623
             Q+ E L    ++   Q+L       Q++L S      Q      +      +A  Q+L
Sbjct: 899 RQQQQEALRRLQQQQQQQQL------AQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKL 952

Query: 624 ASGKE 628
              +E
Sbjct: 953 EEERE 957


>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapiens]
          Length = 1299

 Score =  134 bits (337), Expect = 3e-31
 Identities = 111/455 (24%), Positives = 231/455 (50%), Gaps = 70/455 (15%)

Query: 193  EKLTKERDAPSL--------------ELYRNTITDEELKEKNAELQEKLRLVESEKSEIQ 238
            E+LT++++  +L              + Y   +  ++    +++ Q++L L+  +   ++
Sbjct: 608  ERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTLK 667

Query: 239  LNVKDLKRKLERAQLLLPQQQLQVEADRLGK--ELQSVSAKLQAQVEENELWNLL----- 291
            + + D        Q ++P     V     G   ELQ  +++     E   +W+L      
Sbjct: 668  MRISD--------QNIIPSVTRSVSVPDTGSIWELQPTASQPTVW-EGGSVWDLPLDTTT 718

Query: 292  -NQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQ--EDKM 348
                 E+    ++ K  + E++  E E++ + +EE+  RQEE   +QEE +R Q  E++ 
Sbjct: 719  PGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERK 778

Query: 349  WRQEEKI--REQEEKIREQEEKMWRQEEKIREQ--DEKIQEQEEEMWRQEEKIREQEEKR 404
             R+EE++  R+QEE +R Q E    QE  +R Q  +E+ Q+QEE + R EE+ RE+EE+ 
Sbjct: 779  RREEEELARRKQEEALRRQRE----QEIALRRQREEEERQQQEEALRRLEERRREEEER- 833

Query: 405  QEKMWRQEKKMREQDEKIREQEEE--MWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462
                       R+Q+E +R+QEEE   W +EE+  E +  +++   ++ E   +++ EEE
Sbjct: 834  -----------RKQEELLRKQEEEAAKWAREEE--EAQRRLEENRLRMEEEAARLRHEEE 880

Query: 463  KMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEK---M 519
            + + +E ++QRQ+E +++++++     +L +Q+++  +Q  +M       W Q+      
Sbjct: 881  ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQ--QQLAQMKLPSSSTWGQQSNTTAC 938

Query: 520  QEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESG 579
            Q Q      + +K+ E+  R  ++E++ Q++E+ ++ L+++  +  QK    G   + SG
Sbjct: 939  QSQATLSLAEIQKLEEERERQLREEQRRQQREL-MKALQQQQQQQQQKLSGWGNVSKPSG 997

Query: 580  SQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQ 614
            + +         +E++ +EA+ +Q+QQ   + H Q
Sbjct: 998  TTK-------SLLEIQQEEARQMQKQQQQQQQHQQ 1025



 Score =  110 bits (275), Expect = 4e-24
 Identities = 82/258 (31%), Positives = 146/258 (56%), Gaps = 20/258 (7%)

Query: 378 EQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIR 437
           +Q EK +  + E  R+E ++R + E+ + K  RQE+  R+Q+E +R Q+EE    E K R
Sbjct: 727 QQLEKAKAAKLEQERREAEMRAKREEEERK--RQEELRRQQEEILRRQQEE----ERKRR 780

Query: 438 ELEEMMQ-DQEEKLR-----EVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKL 491
           E EE+ +  QEE LR     E+  + Q EEE+ Q+QEE ++R EE+ +E+EE+  ++E L
Sbjct: 781 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 840

Query: 492 LKQEEKI--W--EQEEKMWRQEE---KMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQE 544
            KQEE+   W  E+EE   R EE   +M E+  +++ +EE+ +R+E +++ Q+  L +Q 
Sbjct: 841 RKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQK-ELMRQR 899

Query: 545 EKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQ 604
           ++ QE   RLQ+ +++      K       G++S +    +   +   E++  E +  +Q
Sbjct: 900 QQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQ 959

Query: 605 QQDHYRGHLQQYVAAYQQ 622
            ++  R   ++ + A QQ
Sbjct: 960 LREEQRRQQRELMKALQQ 977



 Score = 97.4 bits (241), Expect = 4e-20
 Identities = 72/245 (29%), Positives = 133/245 (54%), Gaps = 22/245 (8%)

Query: 395 EKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMM---QDQEEKLR 451
           E++++ E+ +  K+   E++ RE + + + +EEE  RQEE  R+ EE++   Q++E K R
Sbjct: 724 EQLQQLEKAKAAKL---EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 780

Query: 452 EVEE---KMQEEEEKMQEQEE---KIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKM 505
           E EE   + QEE  + Q ++E   + QR+EE+ Q+QEE   R E+  ++EE+  +QEE +
Sbjct: 781 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 840

Query: 506 WRQEEK--MWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGK 563
            +QEE+   W +EE  +E + +++    +M E+  RL  +EE+ + +E+ +Q  +E + +
Sbjct: 841 RKQEEEAAKWAREE--EEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQ 898

Query: 564 LGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQQYVAAYQQL 623
             Q+ E L    ++   Q+L       Q++L S      Q      +      +A  Q+L
Sbjct: 899 RQQQQEALRRLQQQQQQQQL------AQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKL 952

Query: 624 ASGKE 628
              +E
Sbjct: 953 EEERE 957


>gi|239745259 PREDICTED: hypothetical protein isoform 2 [Homo
           sapiens]
          Length = 432

 Score =  133 bits (334), Expect = 6e-31
 Identities = 85/237 (35%), Positives = 148/237 (62%), Gaps = 30/237 (12%)

Query: 231 ESEKSEIQLNVKDLKRKL-----ERAQLLLPQ--------QQLQVEADRLGKELQSVSAK 277
           E +K EI L V+ L R L     + A+ L P+        +QLQ E + L KEL+SV  +
Sbjct: 121 EEKKHEIHL-VQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQ 179

Query: 278 LQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQ 337
           LQA+VE N++ +LLN++QEE++  QEE+++EQEE++ EQE ++ EQEE++  QEE++ EQ
Sbjct: 180 LQAEVENNQMLSLLNRRQEERLREQEERLREQEERLHEQEERLCEQEERLCEQEERLCEQ 239

Query: 338 E-----EKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWR 392
           E     E++ E+ +K+  QE +  EQE  +  + E++  + E++ EQ E++++Q+E +W+
Sbjct: 240 EKLPGQERLLEEVEKLLEQERRQEEQERLL--ERERLLDEVEELLEQ-ERLRQQDERLWQ 296

Query: 393 QE-----EKIREQE---EKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEE 441
           QE     E++RE E   E   E ++ Q  + R   E++  + +   + E++++ELE+
Sbjct: 297 QETLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELEK 353



 Score = 98.6 bits (244), Expect = 2e-20
 Identities = 80/285 (28%), Positives = 154/285 (54%), Gaps = 35/285 (12%)

Query: 258 QQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQE 317
           Q L+ +   L   L S SA + +Q+ EN + +L+   +EEK  + E  + +   K+    
Sbjct: 85  QDLESQYQELAVALDSSSAII-SQLTEN-INSLVRTSKEEK--KHEIHLVQ---KLGRSL 137

Query: 318 LKIREQEEKMWRQE--------EKMHEQEEKIREQEDKMWRQEEKI-----------REQ 358
            K++ Q  +    E        E++ ++   +R++ + + RQ +             R Q
Sbjct: 138 FKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQ 197

Query: 359 EEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEE-KRQEKMWRQEKKMRE 417
           EE++REQEE++  QEE++ EQ+E++ EQEE +  QEE++ EQE+   QE++  + +K+ E
Sbjct: 198 EERLREQEERLREQEERLHEQEERLCEQEERLCEQEERLCEQEKLPGQERLLEEVEKLLE 257

Query: 418 QDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEE-----EKMQEQEEKIQ 472
           Q E+ +E++E +  +E  + E+EE++  ++E+LR+ +E++ ++E     E+++E E  ++
Sbjct: 258 Q-ERRQEEQERLLERERLLDEVEELL--EQERLRQQDERLWQQETLRELERLRELERMLE 314

Query: 473 RQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEE 517
              E + EQ  +     + L  E K   Q E+  ++ EK    EE
Sbjct: 315 LGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELEKSGGAEE 359



 Score = 93.2 bits (230), Expect = 7e-19
 Identities = 67/231 (29%), Positives = 126/231 (54%), Gaps = 32/231 (13%)

Query: 382 KIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQD------------EKIREQEEEM 429
           ++ E    + R  ++ ++ E    +K+ R   K++ Q              K+ + ++E 
Sbjct: 107 QLTENINSLVRTSKEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDET 166

Query: 430 WRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQ- 488
               +++  +   +Q + E  + +    + +EE+++EQEE+++ QEE++ EQEE+   Q 
Sbjct: 167 NHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLHEQEERLCEQE 226

Query: 489 EKLLKQEEKIWEQE-----EKMWRQEEKMWEQEEKMQEQEEKMQR-----------QEEK 532
           E+L +QEE++ EQE     E++  + EK+ EQE + +EQE  ++R           ++E+
Sbjct: 227 ERLCEQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLDEVEELLEQER 286

Query: 533 MREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRL 583
           +R+Q+ RLWQQ E ++E E RL+EL ER+ +LG +A     A   SG + L
Sbjct: 287 LRQQDERLWQQ-ETLRELE-RLREL-ERMLELGWEALYEQRAEPRSGFEEL 334



 Score = 49.7 bits (117), Expect = 9e-06
 Identities = 42/193 (21%), Positives = 98/193 (50%), Gaps = 12/193 (6%)

Query: 195 LTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKL-ERAQL 253
           L KE ++   +L      ++ L   N   +E+LR  E    E +  + + + +L E+ + 
Sbjct: 169 LRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLHEQEERLCEQEER 228

Query: 254 LLPQQQLQVEADRL-GKE--LQSVSAKLQAQVEENELWNLLNQQQ---EEKMWRQEEKIQ 307
           L  Q++   E ++L G+E  L+ V   L+ +  + E   LL +++   E +   ++E+++
Sbjct: 229 LCEQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLDEVEELLEQERLR 288

Query: 308 EQEEKMCEQEL-----KIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKI 362
           +Q+E++ +QE      ++RE E  +    E ++EQ  + R   +++  + +   + E+++
Sbjct: 289 QQDERLWQQETLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQV 348

Query: 363 REQEEKMWRQEEK 375
           +E E+    +E +
Sbjct: 349 KELEKSGGAEEPR 361


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.306    0.124    0.335 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,723,758
Number of Sequences: 37866
Number of extensions: 1722063
Number of successful extensions: 149353
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1821
Number of HSP's successfully gapped in prelim test: 1227
Number of HSP's that attempted gapping in prelim test: 13119
Number of HSP's gapped (non-prelim): 31393
length of query: 655
length of database: 18,247,518
effective HSP length: 109
effective length of query: 546
effective length of database: 14,120,124
effective search space: 7709587704
effective search space used: 7709587704
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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