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Search of human proteins with 239745127
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
(655 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 1303 0.0
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 1301 0.0
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 530 e-150
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 529 e-150
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 529 e-150
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 515 e-146
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 427 e-119
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 422 e-118
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 319 4e-87
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 231 2e-60
gi|239752551 PREDICTED: hypothetical protein [Homo sapiens] 222 7e-58
gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo sap... 184 2e-46
gi|148746195 trichohyalin [Homo sapiens] 180 3e-45
gi|31317305 M-phase phosphoprotein 10 [Homo sapiens] 177 3e-44
gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo sap... 155 1e-37
gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C... 155 1e-37
gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo sapi... 154 2e-37
gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo sapi... 152 1e-36
gi|221219020 NYD-SP11 protein [Homo sapiens] 148 1e-35
gi|194097392 Golgi autoantigen, golgin subfamily a, 2 [Homo sapi... 146 7e-35
gi|169208458 PREDICTED: similar to golgi autoantigen, golgin sub... 140 4e-33
gi|154937324 hypothetical protein LOC440295 [Homo sapiens] 140 4e-33
gi|169210281 PREDICTED: similar to M-phase phosphoprotein 10 (U3... 140 5e-33
gi|169210488 PREDICTED: similar to M-phase phosphoprotein 10 (U3... 140 5e-33
gi|169210051 PREDICTED: similar to M-phase phosphoprotein 10 (U3... 140 5e-33
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 134 3e-31
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 134 3e-31
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 134 3e-31
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 134 3e-31
gi|239745259 PREDICTED: hypothetical protein isoform 2 [Homo sap... 134 3e-31
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 1303 bits (3373), Expect = 0.0
Identities = 655/655 (100%), Positives = 655/655 (100%)
Query: 1 MGGDNPEVSERANSSKFDPTKSPVLSDEDSDLDFHINKLEQQSKVRNKGHGKPREKSIAD 60
MGGDNPEVSERANSSKFDPTKSPVLSDEDSDLDFHINKLEQQSKVRNKGHGKPREKSIAD
Sbjct: 1 MGGDNPEVSERANSSKFDPTKSPVLSDEDSDLDFHINKLEQQSKVRNKGHGKPREKSIAD 60
Query: 61 EKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAG 120
EKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAG
Sbjct: 61 EKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAG 120
Query: 121 VSHVKKNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETL 180
VSHVKKNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETL
Sbjct: 121 VSHVKKNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETL 180
Query: 181 HFDHAVRMGTYIEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLN 240
HFDHAVRMGTYIEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLN
Sbjct: 181 HFDHAVRMGTYIEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLN 240
Query: 241 VKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMW 300
VKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMW
Sbjct: 241 VKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMW 300
Query: 301 RQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEE 360
RQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEE
Sbjct: 301 RQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEE 360
Query: 361 KIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDE 420
KIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDE
Sbjct: 361 KIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDE 420
Query: 421 KIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQE 480
KIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQE
Sbjct: 421 KIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQE 480
Query: 481 QEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRL 540
QEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRL
Sbjct: 481 QEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRL 540
Query: 541 WQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQ 600
WQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQ
Sbjct: 541 WQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQ 600
Query: 601 SLQQQQDHYRGHLQQYVAAYQQLASGKEALPSCSSRKLRAKRWLRWPTNSCRRPS 655
SLQQQQDHYRGHLQQYVAAYQQLASGKEALPSCSSRKLRAKRWLRWPTNSCRRPS
Sbjct: 601 SLQQQQDHYRGHLQQYVAAYQQLASGKEALPSCSSRKLRAKRWLRWPTNSCRRPS 655
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 1301 bits (3366), Expect = 0.0
Identities = 654/655 (99%), Positives = 654/655 (99%)
Query: 1 MGGDNPEVSERANSSKFDPTKSPVLSDEDSDLDFHINKLEQQSKVRNKGHGKPREKSIAD 60
MGGDNPEVSERANSSKFDPTKSPVLSDEDSDLDFHINKLEQQSKVRNKGHGKPREKSIAD
Sbjct: 1 MGGDNPEVSERANSSKFDPTKSPVLSDEDSDLDFHINKLEQQSKVRNKGHGKPREKSIAD 60
Query: 61 EKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAG 120
EKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAG
Sbjct: 61 EKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAG 120
Query: 121 VSHVKKNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETL 180
VSHVKKNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETL
Sbjct: 121 VSHVKKNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETL 180
Query: 181 HFDHAVRMGTYIEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLN 240
HFDHAVRMGTYIEKLTKERDA SLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLN
Sbjct: 181 HFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLN 240
Query: 241 VKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMW 300
VKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMW
Sbjct: 241 VKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMW 300
Query: 301 RQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEE 360
RQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEE
Sbjct: 301 RQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEE 360
Query: 361 KIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDE 420
KIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDE
Sbjct: 361 KIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDE 420
Query: 421 KIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQE 480
KIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQE
Sbjct: 421 KIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQE 480
Query: 481 QEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRL 540
QEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRL
Sbjct: 481 QEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRL 540
Query: 541 WQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQ 600
WQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQ
Sbjct: 541 WQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQ 600
Query: 601 SLQQQQDHYRGHLQQYVAAYQQLASGKEALPSCSSRKLRAKRWLRWPTNSCRRPS 655
SLQQQQDHYRGHLQQYVAAYQQLASGKEALPSCSSRKLRAKRWLRWPTNSCRRPS
Sbjct: 601 SLQQQQDHYRGHLQQYVAAYQQLASGKEALPSCSSRKLRAKRWLRWPTNSCRRPS 655
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 530 bits (1364), Expect = e-150
Identities = 307/472 (65%), Positives = 342/472 (72%), Gaps = 102/472 (21%)
Query: 191 YIEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLER 250
YIE+LTKERDALSLELYRNTITDEELKEKNA+LQEKL+LVESEKSEIQLNVK+LKRKLER
Sbjct: 194 YIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLER 253
Query: 251 AQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQE-- 308
A+LLLPQQQLQ EAD LGKELQSVSAKLQAQVEENELWN LNQQQEEKMWRQEEKIQE
Sbjct: 254 AKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWE 313
Query: 309 -----QEEKMCEQELKIREQEEKMWRQEE------------------------------- 332
QEEK+ EQE KIREQEEKM RQEE
Sbjct: 314 EKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMW 373
Query: 333 -----------KMHEQE------------EKIREQED------KMWRQEEKIREQEEKIR 363
KMHEQE EKIREQE KMWRQEEKIREQEEKIR
Sbjct: 374 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 433
Query: 364 EQEEKMWRQEEKIREQDEKIQEQE-----EEMWRQEEKIREQEE---------------K 403
EQE+KMWRQEEKI EQ EKI+E+E EEMWRQEEKIREQEE K
Sbjct: 434 EQEKKMWRQEEKIHEQ-EKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRK 492
Query: 404 RQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEK 463
++EK+WRQE+KM +Q+EKIREQEE+MWRQEEKIRE EE +++QEEK+RE EE MQE+EEK
Sbjct: 493 QEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEK 552
Query: 464 MQEQEEKIQ------RQEEKIQEQEEKTWRQ-EKLLKQEEKIWEQEEK-------MWRQE 509
M EQEEK+Q RQEEKI+EQEEK Q EK+ +QEEKIWEQEEK M QE
Sbjct: 553 MGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQE 612
Query: 510 EKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERL 561
EKMWEQEEKM EQEEKMQ QEEKMR QE ++W+QE ++++QE ++QE +E L
Sbjct: 613 EKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHL 664
Score = 343 bits (880), Expect = 3e-94
Identities = 219/512 (42%), Positives = 309/512 (60%), Gaps = 82/512 (16%)
Query: 66 LSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVK 125
+++ E +N K + + E + E + K+ K L+R LP + +A H+
Sbjct: 214 ITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEA--DHLG 271
Query: 126 KNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQK--RPENSLLE-ETLHF 182
K E++S K Q ++ E W RL + +K R E + E E
Sbjct: 272 K---ELQSVSAKLQAQVEENEL-----------WNRLNQQQEEKMWRQEEKIQEWEEKIQ 317
Query: 183 DHAVRMGTYIEKLTKERDALSLELYRNTITDEELKEKNA---ELQEKLRLVESEKSEIQL 239
+ ++ EK+ ++ + + + +E+++ + E +EK+R +E E +
Sbjct: 318 EQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEE 377
Query: 240 NVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKM 299
+++L+ K+ + + Q++ + E +++ ++ + Q+QE KM
Sbjct: 378 KIRELEEKMHEQEKIREQEEKRQEEEKIREQEK-------------------RQEQEAKM 418
Query: 300 WRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQE----EKIREQEDKMWRQEEKI 355
WRQEEKI+EQEEK IREQE+KMWRQEEK+HEQE E+ R+++++MWRQEEKI
Sbjct: 419 WRQEEKIREQEEK-------IREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKI 471
Query: 356 REQE------------EKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEK 403
REQE EKIR+QEEK+WRQEEK+ +Q+EKI+EQEE+MWRQEEKIREQEE
Sbjct: 472 REQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEE- 530
Query: 404 RQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEK 463
K+REQ+EKIREQEE M QEEK+ E EE MQ+Q EK+R EEK++E+EEK
Sbjct: 531 ----------KIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQ-EKMRRQEEKIREQEEK 579
Query: 464 MQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQE 523
++EQ+EKI+ QEEKI EQEEK QE++++ EQEEKMW QEEKM EQEEKMQEQE
Sbjct: 580 IREQKEKIREQEEKIWEQEEKIREQEEMMQ------EQEEKMWEQEEKMCEQEEKMQEQE 633
Query: 524 EKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQ 555
EKM+RQEEKM EQEVRL QQEEKMQE + L+
Sbjct: 634 EKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLE 665
Score = 196 bits (498), Expect = 6e-50
Identities = 144/466 (30%), Positives = 238/466 (51%), Gaps = 87/466 (18%)
Query: 21 KSPVLSDEDSDLDFHINKLE-----------QQSKVRNKGHGKPREKSIADEKFFQLSEM 69
K ++ E S++ ++ +L+ QQ H +S++ + Q+ E
Sbjct: 229 KLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEEN 288
Query: 70 EAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSD 129
E + +++ K W +++ ++E E+ Q +E R +E I
Sbjct: 289 ELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIR-----EQEEKIR------------ 331
Query: 130 EVKSSFKKRQEKMNEKNYTFRKRVVI----KKPWLRLGEVTAQKRPENSLLEETLHFDHA 185
E + ++++E M EK R++ + ++ RL E+ +K + LEE +H
Sbjct: 332 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEK 391
Query: 186 VR----MGTYIEKLTKE--RDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQL 239
+R EK+ ++ R +++R E +EK E QEK + EK Q
Sbjct: 392 IREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE-QEKKMWRQEEKIHEQE 450
Query: 240 NVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQ------ 293
+++ +++ E+ ++ +++++ E + + ++ + + + + + +E ++W +
Sbjct: 451 KIREEEKRQEQEEMWRQEEKIR-EQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEE 509
Query: 294 ---QQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEK---------- 340
+QEEKMWRQEEKI+EQEEK+ EQE KIREQEE M QEEKM EQEEK
Sbjct: 510 KIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQ 569
Query: 341 -----------------IREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKI 383
IREQE+K+W QEEKIREQEE ++EQEEKMW QEEK+ EQ+EK+
Sbjct: 570 EEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKM 629
Query: 384 QEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEM 429
QEQEE+M RQE EKMW QE ++R+Q+EK++E +E +
Sbjct: 630 QEQEEKMRRQE-----------EKMWEQEVRLRQQEEKMQEHQEHL 664
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 529 bits (1363), Expect = e-150
Identities = 289/388 (74%), Positives = 324/388 (83%), Gaps = 29/388 (7%)
Query: 191 YIEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLER 250
YIE+LTKERDALSLELYRNTITDEELKEKNA+LQEKL+LVESEKSEIQLNVK+LKRKLER
Sbjct: 182 YIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLER 241
Query: 251 AQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQE 310
A+LLLPQQQLQ EAD LGKELQSVSAKLQAQVEENELWN LNQQQEEKMWRQEEKIQE+E
Sbjct: 242 AKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQERE 301
Query: 311 EKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIRE------QEEKIRE 364
EK+ EQE KIREQEEKM RQEE M E+EEK+R QE+ MW +EEKIRE ++EKIRE
Sbjct: 302 EKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIRE 361
Query: 365 QEE-------------------KMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEK-- 403
QEE KMWRQEEKIREQ+EKI+EQEE M QEEK+ EQEEK
Sbjct: 362 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMW 421
Query: 404 -RQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462
++E+M QE+KMR Q+EKIREQE+++ QEEKIRE EEMMQ+QEEK+ E E KM E+E
Sbjct: 422 EQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEA 481
Query: 463 KMQEQEEKIQRQEEKIQEQEEKTWRQ-EKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQE 521
KMQEQEEK++RQEEKI+EQE+K Q EK+ +QEE + EQEEKMW QEEKM EQEEKMQE
Sbjct: 482 KMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 541
Query: 522 QEEKMQRQEEKMREQEVRLWQQEEKMQE 549
QEEKM+RQEEKMREQEVRL QQEEKMQE
Sbjct: 542 QEEKMRRQEEKMREQEVRLRQQEEKMQE 569
Score = 198 bits (503), Expect = 1e-50
Identities = 146/431 (33%), Positives = 225/431 (52%), Gaps = 91/431 (21%)
Query: 21 KSPVLSDEDSDLDFHINKLE-----------QQSKVRNKGHGKPREKSIADEKFFQLSEM 69
K ++ E S++ ++ +L+ QQ H +S++ + Q+ E
Sbjct: 217 KLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEEN 276
Query: 70 EAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSD 129
E + +++ K W +++ ++E E+ Q +E R
Sbjct: 277 ELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIR------------------------ 312
Query: 130 EVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMG 189
E + ++++E M EK R++ E+ +K + LEE +H +R
Sbjct: 313 EQEEKMRRQEEMMWEKEEKMRRQE----------EMMWEKEEKIRELEEKMHEQEKIR-- 360
Query: 190 TYIEKLTKERDALSLELYRNTITDEELKE--KNAELQEKLRLVESEKSEIQLNVKDLKRK 247
E+ K ++ +E+++E K E + K+ E + E + +++
Sbjct: 361 ---EQEEKRQE------------EEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE---- 401
Query: 248 LERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQ 307
++ +Q + +++G++ K+ Q EE Q+QEEKM RQEEKI+
Sbjct: 402 --------QEEMMQEQEEKMGEQ----EEKMWEQEEE-------MQEQEEKMRRQEEKIR 442
Query: 308 EQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEE 367
EQE+K+ EQE KIREQEE M QEEKM EQE K+ EQE KM QEEK+R QEEKIREQE+
Sbjct: 443 EQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEK 502
Query: 368 KMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEE 427
K+ QEEKIREQ+E +QEQEE+MW QEEK+ EQEEK QE QE+KMR Q+EK+REQE
Sbjct: 503 KIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE----QEEKMRRQEEKMREQEV 558
Query: 428 EMWRQEEKIRE 438
+ +QEEK++E
Sbjct: 559 RLRQQEEKMQE 569
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 529 bits (1362), Expect = e-150
Identities = 304/467 (65%), Positives = 338/467 (72%), Gaps = 97/467 (20%)
Query: 191 YIEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLER 250
YIE+LTKERDALSLELYRNTITDEELKEKNA+LQEKL+LVESEKSEIQLNVK+LKRKLER
Sbjct: 255 YIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLER 314
Query: 251 AQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQE-- 308
A+LLLPQQQLQ EAD LGKELQSVSAKLQAQVEENELWN LNQQQEEKMWRQEEKIQE
Sbjct: 315 AKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWE 374
Query: 309 -----QEEKMCEQELKIREQEEKMWRQEE------------------------------- 332
QEEK+ EQE KIREQEEKM RQEE
Sbjct: 375 EKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMW 434
Query: 333 -----------KMHEQE------------EKIREQED------KMWRQEEKIREQEEKIR 363
KMHEQE EKIREQE KMWRQEEKIREQEEKIR
Sbjct: 435 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 494
Query: 364 EQEEKMWRQEEKIREQDEKIQEQE-----EEMWRQEEKIREQEE---------------- 402
EQEEKMWRQEEKI EQ EKI+E+E EEMWRQEEKIREQEE
Sbjct: 495 EQEEKMWRQEEKIHEQ-EKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIR 553
Query: 403 KRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462
K++EKMWRQE+KM +Q+EKIREQEE++WRQEEKIRE EE +++QEEK+RE EE QE+EE
Sbjct: 554 KQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEE 613
Query: 463 KMQEQEEKIQRQEEKIQEQEEKTWRQE--------KLLKQEEKIWEQEEKMWRQEEKMWE 514
KM EQEEK+ QEEK+QEQEEK RQE K+ +QEEKI EQEE M QEEKMWE
Sbjct: 614 KMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWE 673
Query: 515 QEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERL 561
QEEKM EQEEKMQ QEEKMR QE ++W+QE ++++QE ++QE +E L
Sbjct: 674 QEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHL 720
Score = 327 bits (838), Expect = 2e-89
Identities = 206/493 (41%), Positives = 298/493 (60%), Gaps = 72/493 (14%)
Query: 66 LSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVK 125
+++ E +N K + + E + E + K+ K L+R LP + +A H+
Sbjct: 275 ITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEA--DHLG 332
Query: 126 KNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQK--RPENSLLE-ETLHF 182
K E++S K Q ++ E W RL + +K R E + E E
Sbjct: 333 K---ELQSVSAKLQAQVEENEL-----------WNRLNQQQEEKMWRQEEKIQEWEEKIQ 378
Query: 183 DHAVRMGTYIEKLTKERDALSLELYRNTITDEELKEKNA---ELQEKLRLVESEKSEIQL 239
+ ++ EK+ ++ + + + +E+++ + E +EK+R E E +
Sbjct: 379 EQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 438
Query: 240 NVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKM 299
+++L+ K+ + + Q++ + E +++ ++ + Q+QE KM
Sbjct: 439 KIRELEEKMHEQEKIREQEEKRQEEEKIREQEK-------------------RQEQEAKM 479
Query: 300 WRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIRE------------QEDK 347
WRQEEKI+EQEEK IREQEEKMWRQEEK+HEQE KIRE QE+K
Sbjct: 480 WRQEEKIREQEEK-------IREQEEKMWRQEEKIHEQE-KIREEEKRQEQEEMWRQEEK 531
Query: 348 M------WRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQE 401
+ WRQ+EKI EQEEKIR+QEEKMWRQEEK+ +Q+EKI+EQEE++WRQEEKIREQE
Sbjct: 532 IREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQE 591
Query: 402 EKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEE 461
EK +E QE+K+REQ+E +EQEE+M QEEK+ E EE MQ+QEEK+R EEK++E+E
Sbjct: 592 EKIRE----QEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQE 647
Query: 462 EKMQEQEEKIQRQEEKIQEQEEKTWRQ-EKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQ 520
+K++EQEEKI+ QEE +QEQEEK W Q EK+ +QEEK+ EQEEKM RQEEKMWEQE +++
Sbjct: 648 KKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLR 707
Query: 521 EQEEKMQRQEEKM 533
+QEEKMQ +E +
Sbjct: 708 QQEEKMQEHQEHL 720
Score = 221 bits (562), Expect = 2e-57
Identities = 157/462 (33%), Positives = 249/462 (53%), Gaps = 63/462 (13%)
Query: 21 KSPVLSDEDSDLDFHINKLE-----------QQSKVRNKGHGKPREKSIADEKFFQLSEM 69
K ++ E S++ ++ +L+ QQ H +S++ + Q+ E
Sbjct: 290 KLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEEN 349
Query: 70 EAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSD 129
E + +++ K W +++ ++E E+ Q +E R +E I
Sbjct: 350 ELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIR-----EQEEKIR------------ 392
Query: 130 EVKSSFKKRQEKMNEKNYTFRKRVVI----KKPWLRLGEVTAQKRPENSLLEETLHFDHA 185
E + ++++E M EK R++ + ++ R E+ +K + LEE +H
Sbjct: 393 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEK 452
Query: 186 VR----MGTYIEKLTKE--RDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQL 239
+R EK+ ++ R +++R E +EK E +EK+ E EK Q
Sbjct: 453 IREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQE-EKIHEQE 511
Query: 240 NVKDLKRKLERAQLLLPQQQL--QVEADRLGKELQSVSAKLQAQVEENELWNLLNQ---- 293
+++ +++ E+ ++ ++++ Q E R +++ K++ Q E ++W +
Sbjct: 512 KIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQ--EEKMWRQEEKMHDQ 569
Query: 294 -----QQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKM 348
+QEEK+WRQEEKI+EQEEK+ EQE KIREQEE QEEKM EQEEK+ EQE+KM
Sbjct: 570 EEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKM 629
Query: 349 WRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKM 408
QEEK+R QEEKIREQE+K+ QEEKIREQ+E +QEQEE+MW QEEK+ EQEE
Sbjct: 630 QEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE------ 683
Query: 409 WRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKL 450
KM+EQ+EK+R QEE+MW QE ++R+ EE MQ+ +E L
Sbjct: 684 -----KMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHL 720
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 515 bits (1327), Expect = e-146
Identities = 291/496 (58%), Positives = 361/496 (72%), Gaps = 58/496 (11%)
Query: 191 YIEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLER 250
YIE+LTKERDALSLELYRNTITDEELKEKNA+LQEKL+LVESEKSEIQLNVK+LKRKLER
Sbjct: 194 YIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLER 253
Query: 251 AQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQ-------E 303
A+LLLPQQQLQ EAD LGKELQSVSAKLQAQVEENELWN LNQQQEEKMWRQ E
Sbjct: 254 AKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWE 313
Query: 304 EKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIR------- 356
EKIQEQEEK+ EQE KIREQEEKM RQEE M E+EEK+R QE+ MW +EEK+R
Sbjct: 314 EKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMW 373
Query: 357 EQEEKIREQEEKMWRQEEKIREQDEKI-------------------------QEQEEEMW 391
E+EEK+R QEE MW +EEKIRE +EK+ QEQE +MW
Sbjct: 374 EKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMW 433
Query: 392 RQEEKIREQEEK---RQEKMWRQEKKMREQDEKIREQE-----EEMWRQEEKIRELEEMM 443
RQEEKIREQEEK +++KMWRQE+K+ EQ EKIRE+E EEMWRQEEKI E EE+
Sbjct: 434 RQEEKIREQEEKIREQEKKMWRQEEKIHEQ-EKIREEEKRQEQEEMWRQEEKIHEQEEIW 492
Query: 444 QDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEE 503
+ Q+EK+ E EEK++++EEK+ QEEKI+ QEEKI+EQEEK WRQE+ ++++E++W +EE
Sbjct: 493 R-QKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEE 551
Query: 504 KMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGK 563
KM ++EK+WE EEK QEQE+KM RQEEK+REQE ++W+QEEK++EQE + QE EE++ K
Sbjct: 552 KM-HEQEKIWE-EEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWK 609
Query: 564 LGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQQYVAAYQQL 623
+K RE + I + E K +E + + Q+Q+ G ++ + ++
Sbjct: 610 QEEKI-------REQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEK 662
Query: 624 ASGKEALPSCSSRKLR 639
+E K+R
Sbjct: 663 MQEQEETMWRQEEKIR 678
Score = 391 bits (1004), Expect = e-108
Identities = 242/539 (44%), Positives = 332/539 (61%), Gaps = 58/539 (10%)
Query: 66 LSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVK 125
+++ E +N K + + E + E + K+ K L+R LP + +A H+
Sbjct: 214 ITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEA--DHLG 271
Query: 126 KNSDEVKSSFKKRQEK---MNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHF 182
K V + + + E+ N N +++ ++ ++ E Q++ E +E
Sbjct: 272 KELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIR 331
Query: 183 DHAVRMGTYIEKLTKERDALSLELYRNTITDEELKEKNA---ELQEKLRLVESEKSEIQL 239
+ +M E + ++ + + + +E+++ + E +EK+R E E +
Sbjct: 332 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 391
Query: 240 NVKDLKRKLERAQLLLPQQQLQVEADRLGKE--LQSVSAKLQAQVEENELWNLLNQQQEE 297
+++L+ K+ + + Q++ + E +++ ++ Q AK+ Q E+ ++QE+
Sbjct: 392 KIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEK 451
Query: 298 KMWRQEEKIQEQE-----------EKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQED 346
KMWRQEEKI EQE E+M QE KI EQEE +WRQ+EKMHEQEEKIR+QE+
Sbjct: 452 KMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEE-IWRQKEKMHEQEEKIRKQEE 510
Query: 347 KMWRQEEKIREQEEKIREQEEKMWRQEEKIRE---------------------------- 378
K+WRQEEKIREQEEKIREQEEKMWRQEEKIRE
Sbjct: 511 KVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQED 570
Query: 379 ----QDEKIQEQEEEMWRQEEKIREQEEKRQ---EKMWRQEKKMREQDEKIREQEEEMWR 431
Q+EKI+EQEE++WRQEEKIREQEEKRQ EKMW+QE+K+REQ+EKI+EQEE++
Sbjct: 571 KMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIRE 630
Query: 432 QEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQ-EK 490
QEEKIRE EEM Q+QEEK+ E EEKM E+EEKMQEQEE + RQEEKI+EQE+K Q EK
Sbjct: 631 QEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEK 690
Query: 491 LLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQE 549
+ +QEE + EQEEKMW QEEKM EQEEKMQEQEEKM+RQEEKM EQEVRL QQEEKMQE
Sbjct: 691 IREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
Score = 248 bits (632), Expect = 2e-65
Identities = 159/435 (36%), Positives = 248/435 (57%), Gaps = 85/435 (19%)
Query: 38 KLEQQSKVRNKGHGKPREKSIADEKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSK 97
K+ +Q K+R + + E+ I ++ E R+ + K W +++ + E E+
Sbjct: 399 KMHEQEKIREQEEKRQEEEKIREQ------------EKRQEQEAKMWRQEEKIREQEE-- 444
Query: 98 QCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKK 157
+ +E K++ +E I + QEK+ E+ KR ++
Sbjct: 445 KIREQEKKM---WRQEEKIHE--------------------QEKIREE----EKRQEQEE 477
Query: 158 PWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDALSLELYRNTITDEELK 217
W R E + E+ E++ ++++ + E +
Sbjct: 478 MW----------RQEEKIHEQ--------------EEIWRQKEKM-----------HEQE 502
Query: 218 EKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAK 277
EK + +EK+ E + E + +++ + K+ R + + +Q+ + E + + +
Sbjct: 503 EKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEE 562
Query: 278 LQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQ 337
+ Q +E+++W +QEEK+ QEEK+ QEEK+ EQE K +EQEEKMW+QEEK+ EQ
Sbjct: 563 EKRQEQEDKMW-----RQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQ 617
Query: 338 EEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKI 397
EEKI+EQE+K+ QEEKIREQEE +EQEEKM QEEK+ EQ+EK+QEQEE MWRQEEKI
Sbjct: 618 EEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKI 677
Query: 398 REQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKM 457
REQE+K +E QE+K+REQ+E ++EQEE+MW QEEK+ E EE MQ+QEEK+R EEKM
Sbjct: 678 REQEKKIRE----QEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKM 733
Query: 458 QEEEEKMQEQEEKIQ 472
E+E ++++QEEK+Q
Sbjct: 734 WEQEVRLRQQEEKMQ 748
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 427 bits (1097), Expect = e-119
Identities = 229/389 (58%), Positives = 304/389 (78%), Gaps = 43/389 (11%)
Query: 191 YIEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLER 250
YIE+LTKERDALSLELYRNTIT+EELK+KNAELQEKLRL ESEKSEIQLNVK+LKRKLER
Sbjct: 160 YIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLER 219
Query: 251 AQLLLPQQQ---LQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQ 307
A+ LLPQ Q LQ E R +EL+ K+ ++QEEKMWRQEE+++
Sbjct: 220 AKFLLPQVQTNTLQEEMWRQEEELREQEKKI--------------RKQEEKMWRQEERLR 265
Query: 308 EQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEE 367
EQE KM REQEEKM RQE+++ EQE+++REQE ++ R+++K+REQEE+++EQEE
Sbjct: 266 EQEGKM-------REQEEKMRRQEKRLREQEKELREQEKEL-REQKKLREQEEQMQEQEE 317
Query: 368 KMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEK---RQEKMWRQEKKMREQDEKIRE 424
KMW QEEK+REQ+EK+ QEE +W QE+++REQE+K ++E+MW Q++++RE++E++RE
Sbjct: 318 KMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMRE 377
Query: 425 QEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEK------I 478
Q E+MW QEEK++E EE ++++E+K+RE EE M+E+EEKMQ+QEE + QEEK +
Sbjct: 378 Q-EKMWEQEEKMQE-EERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRL 435
Query: 479 QEQEEKTWRQEKLLKQEEKIWEQEEK------MWRQEEKMWEQEEKMQEQEEKMQRQEEK 532
EQ+EK W QEK+ +QEEKIWEQEEK MW QE+KMW Q EKM+EQE++M QEEK
Sbjct: 436 PEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQ-EKMREQEDQMWEQEEK 494
Query: 533 MREQEVRLWQQEEKMQEQEVRLQELEERL 561
MR+QE ++W QEE+M EQ+ RL+E EER+
Sbjct: 495 MRDQEQKMWDQEERMWEQDERLREKEERM 523
Score = 348 bits (894), Expect = 7e-96
Identities = 222/561 (39%), Positives = 347/561 (61%), Gaps = 58/561 (10%)
Query: 21 KSPVLSDEDSDLDFHINKLEQQSKVRNKGHGKPREKSIADEKFFQLSEMEAYLENRKRRG 80
K + E S++ ++ +L+++ + + + ++ +E + Q E+ + +++
Sbjct: 195 KLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQE 254
Query: 81 TKRWDEDDDLEESEDS-KQCKESLKRVTFTLPDDEAI--EDAGVSHVKKNSDEVKSSFKK 137
K W +++ L E E ++ +E ++R L + E E +K E + ++
Sbjct: 255 EKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQE 314
Query: 138 RQEKMNEKNYTFRKRVVIKKPWL---RLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEK 194
++EKM E+ R++ +K W RL E Q R + + D RM E+
Sbjct: 315 QEEKMWEQEEKMREQE--EKMWRQEERLWEQEKQMREQEQKMR-----DQEERMWEQDER 367
Query: 195 LTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLL 254
L ++ + + + E++ E+ ++QE+ R+ E EK K + E +
Sbjct: 368 LREKEERMREQ--------EKMWEQEEKMQEEERIREREK----------KMREEEETMR 409
Query: 255 LPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMC 314
++++Q + + + ++ EE E +Q+EK+W QE K+QEQEEK+
Sbjct: 410 EQEEKMQKQEENMWEQ------------EEKEWQQQRLPEQKEKLWEQE-KMQEQEEKIW 456
Query: 315 EQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEE 374
EQE KIR+QEE MW QE+KM QE K+REQED+MW QEEK+R+QE+K+ +QEE+MW Q+E
Sbjct: 457 EQEEKIRDQEE-MWGQEKKMWRQE-KMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDE 514
Query: 375 KIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEE 434
++RE++E+++EQ ++MW+QEEK+RE E+K QE QEKK +Q+EK+RE EE M +E+
Sbjct: 515 RLREKEERMREQ-KKMWQQEEKMRE-EKKTQE----QEKKTWDQEEKMRE-EERMREREK 567
Query: 435 KIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQE---KL 491
K+RE EEMM++QEEK++E EEKM+E+EEKM EQEEK+Q QEEK+ EQEEK W QE K+
Sbjct: 568 KMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKM 627
Query: 492 LKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQE 551
+QEE +WEQEEKM QEEKMWEQEEKM+EQEEKM+ QEEKM+ QE ++ +QEEKMQ QE
Sbjct: 628 QEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQE 687
Query: 552 VRLQELEERLGKLGQKAELLG 572
+++E EE++ GQ+ ++ G
Sbjct: 688 EKMREQEEKM--RGQEEKMWG 706
Score = 203 bits (517), Expect = 4e-52
Identities = 125/383 (32%), Positives = 224/383 (58%), Gaps = 51/383 (13%)
Query: 272 QSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQE 331
+++ +++AQ + + E ++ ++ ++ E+ + + + W
Sbjct: 81 EALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGESKDLAGRLHHSWHFA 140
Query: 332 EKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQ----- 386
++ + K R E++ ++ + + + + E++++++ ++QE+
Sbjct: 141 GELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAE 200
Query: 387 --------------------------------EEEMWRQEEKIREQEE---KRQEKMWRQ 411
+EEMWRQEE++REQE+ K++EKMWRQ
Sbjct: 201 SEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQ 260
Query: 412 EKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKI 471
E+++REQ+ K+REQEE+M RQE+++RE E+ +++QE++LRE ++K++E+EE+MQEQEEK+
Sbjct: 261 EERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELRE-QKKLREQEEQMQEQEEKM 319
Query: 472 QRQEEKIQEQEEKTWRQ-EKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQE------E 524
QEEK++EQEEK WRQ E+L +QE+++ EQE+KM QEE+MWEQ+E+++E+E E
Sbjct: 320 WEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQE 379
Query: 525 KMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLP 584
KM QEEKM+E+E R+ ++E+KM+E+E ++E EE++ K Q+ + +E QRLP
Sbjct: 380 KMWEQEEKMQEEE-RIREREKKMREEEETMREQEEKMQK--QEENMWEQEEKEWQQQRLP 436
Query: 585 TLTPILQVELKSQEAQSLQQQQD 607
L + K QE + +Q+
Sbjct: 437 EQKEKLWEQEKMQEQEEKIWEQE 459
Score = 200 bits (508), Expect = 4e-51
Identities = 137/432 (31%), Positives = 239/432 (55%), Gaps = 51/432 (11%)
Query: 38 KLEQQSKVRNKGHGKPREKSIADEKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSK 97
+L +Q K + K R++ +E+ ++ E E R R K W++++ ++E E +
Sbjct: 339 RLWEQEKQMREQEQKMRDQ---EERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIR 395
Query: 98 QCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEV---------------KSSFKKRQEKM 142
+ ++ ++ T+ + E ++ + ++ + ++++EK+
Sbjct: 396 EREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKI 455
Query: 143 NEKNYTFRKRVVI----KKPW----LRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEK 194
E+ R + + KK W +R E ++ E +E +D RM E+
Sbjct: 456 WEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDER 515
Query: 195 LTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLL 254
L ++ + + + ++ +EK + QEK + EK + +++ ++K+ + +
Sbjct: 516 LREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEM 575
Query: 255 LPQQQ--LQVEADRLGKELQSV-SAKLQAQVEENELWNLLNQQQEEKMWRQEE--KIQEQ 309
+ +Q+ +Q + +++ ++ + + + + Q +E ++W +QEEKMW QEE K+QEQ
Sbjct: 576 MREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMW-----EQEEKMWEQEEEDKMQEQ 630
Query: 310 EEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKM 369
EE M EQE K++EQEEKMW QEEKM EQEEK+REQE+KM QEEK+REQEEK++ QEEKM
Sbjct: 631 EEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKM 690
Query: 370 WRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEM 429
QEEK+R Q+EK+ QEE+MW QE EKMW QE +MRE++E+IR+Q+E+M
Sbjct: 691 REQEEKMRGQEEKMWGQEEKMWGQE-----------EKMWGQE-EMREKEERIRDQKEKM 738
Query: 430 WRQEEKIRELEE 441
+E++ E EE
Sbjct: 739 ---QERLPEHEE 747
Score = 134 bits (337), Expect = 3e-31
Identities = 95/339 (28%), Positives = 182/339 (53%), Gaps = 28/339 (8%)
Query: 294 QQEEKMWRQEEKIQEQEEKMCEQELKI-----REQEEKMWRQEEKMHEQEE-KIREQED- 346
+ E+K Q ++ +E + + ++I E E ++ ++ + E+ + E +D
Sbjct: 70 EDEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGESKDL 129
Query: 347 -----KMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQE 401
W +++ + +K R E++ ++ + + + E+++++
Sbjct: 130 AGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKN 189
Query: 402 EKRQEKMWRQEKKMREQDEKIREQEEEMWRQ-----EEKIRELEEMMQDQEEKLREVEEK 456
+ QEK+ E + E ++E + ++ R + + L+E M QEE+LRE E+K
Sbjct: 190 AELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKK 249
Query: 457 MQEEEEKMQE-----QEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEK 511
+ + QE QEE+++ QE K++EQEEK RQEK L+++EK ++EK R+++K
Sbjct: 250 I-----RKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKK 304
Query: 512 MWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELL 571
+ EQEE+MQEQEEKM QEEKMREQE ++W+QEE++ EQE +++E E+++ ++
Sbjct: 305 LREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQ 364
Query: 572 GGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYR 610
RE +R+ + + E K QE + +++++ R
Sbjct: 365 DERLREK-EERMREQEKMWEQEEKMQEEERIREREKKMR 402
Score = 41.6 bits (96), Expect = 0.002
Identities = 51/279 (18%), Positives = 118/279 (42%), Gaps = 38/279 (13%)
Query: 395 EKIREQEEKRQEKMWRQEKKMRE---QDEKIR-------EQEEEMWRQEEKIRELEEMMQ 444
E E++++ QE RE QD IR E E ++ ++ R+ E+
Sbjct: 64 EGCHSPEDEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNL 123
Query: 445 DQEEKLR-------EVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEE--------KTWRQE 489
+ + L ++Q + +K R E++ ++ + T E
Sbjct: 124 GESKDLAGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNE 183
Query: 490 KLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVR-----LWQQE 544
+L K+ ++ +EK+ E + E + ++E + K++R + + + + +W+QE
Sbjct: 184 ELKKKNAEL---QEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQE 240
Query: 545 EKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQ 604
E+++EQE ++++ EE++ + ++ G RE + + + E + +E + +
Sbjct: 241 EELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELR 300
Query: 605 QQDHYRGHLQQYVAAYQQLASGKEALPSCSSRKLRAKRW 643
+Q R +Q +++ +E + R+ K W
Sbjct: 301 EQKKLREQEEQMQEQEEKMWEQEEKM-----REQEEKMW 334
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 422 bits (1085), Expect = e-118
Identities = 250/505 (49%), Positives = 334/505 (66%), Gaps = 106/505 (20%)
Query: 191 YIEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLER 250
YIE+LTKERDALSLELYRNTIT+EELK+KNAELQEKL L ESEKSEIQLNVK+LKRKLER
Sbjct: 198 YIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLER 257
Query: 251 AQLLLPQQQ---LQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQ 307
A+ LLPQ Q LQ E R +EL+ K++ Q E ++W +QEE++ QE K++
Sbjct: 258 AKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQ--EEKMW-----RQEERLREQEGKMR 310
Query: 308 EQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEE 367
EQEEKM QE ++REQE+++ QE+++ EQ+E +REQE++M QEEK+ EQEEK+REQEE
Sbjct: 311 EQEEKMWRQEKRLREQEKELREQEKELREQKE-LREQEEQMQEQEEKMWEQEEKMREQEE 369
Query: 368 KMWRQEEKI-------REQDEKIQEQEEEMWRQEEKIREQEE--KRQEKMW------RQE 412
KMWRQEE++ REQ++K+++QEE MW Q+E++RE+EE + QEKMW R+E
Sbjct: 370 KMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREE 429
Query: 413 KKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQE------------- 459
KKM+EQ++K R+QEE+M ++EE+IRE E+ M+++EE +RE EEKMQ+
Sbjct: 430 KKMQEQEKKTRDQEEKM-QEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEW 488
Query: 460 -------------EEEKMQEQEEKIQRQEEKIQEQEE------KTWRQEKLLKQEEKIWE 500
E+EKMQEQEEKI QEEKI++QEE K WRQEK+ +QE+++WE
Sbjct: 489 QQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWE 548
Query: 501 QEEKMWRQEEKMWEQEEKMQ--------------------------------------EQ 522
QEEKM QE+KMW+QEE+M+ EQ
Sbjct: 549 QEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQ 608
Query: 523 EEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQR 582
EEKMQ QEEKM+EQE ++W+QEEKMQEQE ++ E EE++ + +K QR
Sbjct: 609 EEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKM---------WEQQR 659
Query: 583 LPTLTPILQVELKSQEAQSLQQQQD 607
LP L K QE + +Q+Q++
Sbjct: 660 LPEQKEKLWEHEKMQEQEKMQEQEE 684
Score = 345 bits (884), Expect = 1e-94
Identities = 231/672 (34%), Positives = 384/672 (57%), Gaps = 99/672 (14%)
Query: 21 KSPVLSDEDSDLDFHINKLEQQSKVRNKGHGKPREKSIADEKFFQLSEMEAYLENRKRRG 80
K P+ E S++ ++ +L+++ + + + ++ +E + Q E+ + +++
Sbjct: 233 KLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQE 292
Query: 81 TKRWDEDDDLEESEDS-KQCKESLKRVTFTLPDDEAI--EDAGVSHVKKNSDEVKSSFKK 137
K W +++ L E E ++ +E + R L + E E +K E + ++
Sbjct: 293 EKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQE 352
Query: 138 RQEKMNEKNYTFRKRVVIKKPWL---RLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEK 194
++EKM E+ R++ +K W RL E Q R + + D RM E+
Sbjct: 353 QEEKMWEQEEKMREQE--EKMWRQEERLWEQEKQMREQEQKMR-----DQEERMWEQDER 405
Query: 195 LTKERDAL--------SLELYRNTITDEELKEKNAELQEKL----RLVESEKS--EIQLN 240
L ++ + + +E R +E ++K + +EK+ R+ E EK E +
Sbjct: 406 LREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEET 465
Query: 241 VKDLKRKLERAQL-LLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWN----LLNQQ- 294
+++ + K+++ + + Q++ + + RL ++ + + + + Q +E ++W + +Q+
Sbjct: 466 MREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEE 525
Query: 295 ---QEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMW----------------------- 328
QE+KMWRQE K++EQE++M EQE K+R+QE+KMW
Sbjct: 526 MWGQEKKMWRQE-KMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEK 584
Query: 329 -RQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQE 387
R+EE+M E+E+K+RE+E+ M QEEK++EQEEK++EQEEKMW QEEK++EQ+EK+ EQE
Sbjct: 585 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQE 644
Query: 388 EEMWRQEEKIREQEE--KRQEKMWRQEK-----KMREQDEKIREQE-------------- 426
E+MW QEEK+ EQ+ +++EK+W EK KM+EQ+EKI EQE
Sbjct: 645 EKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTW 704
Query: 427 -EEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKT 485
+E R+EE +RE E+ M+++EE +RE EEKMQE+EEKMQEQEE++ QEEK+ EQEEK
Sbjct: 705 DQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKM 764
Query: 486 WRQEKLLKQEEKIWEQE-----EKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRL 540
W Q++L +Q+EK+WE E EK+W QEEKM +QEEKM+ QEEKM+ QEEKMR QE ++
Sbjct: 765 WEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKM 824
Query: 541 WQQEEKMQEQEVRLQELEERL-GKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEA 599
W QEEKM QE ++ EE++ G+ + E + G + Q + +++ QE
Sbjct: 825 WGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQ---------EEKMRGQE- 874
Query: 600 QSLQQQQDHYRG 611
+ +++Q++ RG
Sbjct: 875 EKMREQEEKMRG 886
Score = 329 bits (844), Expect = 4e-90
Identities = 221/587 (37%), Positives = 336/587 (57%), Gaps = 111/587 (18%)
Query: 40 EQQSKVRNKGHGKPREKSIADEKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQC 99
EQ+ K+R + R++ E+ Q+ E E + +++ R W++D+ L E E+ +
Sbjct: 359 EQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEER---MWEQDERLREKEERMRE 415
Query: 100 KESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSS-----FKKRQEKMNEKNYTFRKRVV 154
+E + + +++ +++ KK D+ + ++R++KM E+ T R++
Sbjct: 416 QEKMWEQVEKMREEKKMQE----QEKKTRDQEEKMQEEERIREREKKMREEEETMREQ-- 469
Query: 155 IKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDALSLELYRNTITDE 214
E QK+ EN +E + R+ EKL ++ +
Sbjct: 470 ---------EEKMQKQEENMWEQEEKEWQQQ-RLPEQKEKLWEQEKM------------Q 507
Query: 215 ELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSV 274
E +EK E +EK+R ++ E+ K + R Q++++ + D++ ++ + +
Sbjct: 508 EQEEKIWEQEEKIR----DQEEMWGQEKKMWR----------QEKMREQEDQMWEQEEKM 553
Query: 275 SAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKM 334
+ Q ++ E Q+QE+K W QEEK++E EE+M E+E K+RE+EE M QEEKM
Sbjct: 554 RDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMRE-EERMREREKKMREEEEMMREQEEKM 612
Query: 335 HEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQD-------------- 380
EQEEK++EQE+KMW QEEK++EQEEK+ EQEEKMW QEEK+ EQ
Sbjct: 613 QEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEK 672
Query: 381 ----EKIQEQEEEMWRQE----------------EKIREQEEKRQ---------EKMWRQ 411
EK+QEQEE++W QE EK+RE+E R+ E M Q
Sbjct: 673 MQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQ 732
Query: 412 EKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQE------------EKLREVEEKMQE 459
E+KM+EQ+EK++EQEEEMW QEEK+ E EE M +Q+ EK++E +EK+ E
Sbjct: 733 EEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQE-QEKIWE 791
Query: 460 EEEKMQEQEEKIQRQEEKIQEQEEK-TWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEK 518
+EEKM++QEEK++ QEEK++ QEEK ++EK+ QEEK+W QEEKMW QEEKMW QEEK
Sbjct: 792 QEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEK 851
Query: 519 MQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLG 565
M EEKMQ QEEKMREQE ++ QEEKM+EQE +++ EE++ +G
Sbjct: 852 M---EEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEKIYCVG 895
Score = 204 bits (518), Expect = 3e-52
Identities = 125/346 (36%), Positives = 203/346 (58%), Gaps = 69/346 (19%)
Query: 328 WRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQ- 386
W ++ + + K R E++ ++ + + + + E++++++ ++QE+
Sbjct: 175 WHFAGELQRALSAVSTRHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKL 234
Query: 387 ------------------------------------EEEMWRQEEKIREQEE---KRQEK 407
+EEMWRQEE++REQE+ K++EK
Sbjct: 235 PLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEK 294
Query: 408 MWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQE------EKLREVEEKMQEEE 461
MWRQE+++REQ+ K+REQEE+MWRQE+++RE E+ +++QE ++LRE EE+MQE+E
Sbjct: 295 MWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQE 354
Query: 462 EKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLK-QEEKIWEQEEKMW-------------R 507
EKM EQEEK++ QEEK+ QEE+ W QEK ++ QE+K+ +QEE+MW R
Sbjct: 355 EKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMR 414
Query: 508 QEEKMWEQ------EEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERL 561
++EKMWEQ E+KMQEQE+K + QEEKM+E+E R+ ++E+KM+E+E ++E EE++
Sbjct: 415 EQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEE-RIREREKKMREEEETMREQEEKM 473
Query: 562 GKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQD 607
K Q+ + +E QRLP L + K QE + +Q+
Sbjct: 474 QK--QEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQE 517
Score = 147 bits (372), Expect = 2e-35
Identities = 90/271 (33%), Positives = 163/271 (60%), Gaps = 14/271 (5%)
Query: 349 WRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKM 408
W +++ + + +K R E++ ++ + + + E+++++ + QEK+
Sbjct: 175 WHFAGELQRALSAVSTRHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKL 234
Query: 409 WRQEKKMREQDEKIREQEEEMWRQ-----EEKIRELEEMMQDQEEKLREVEEKMQEEEEK 463
E + E ++E + ++ R + + L+E M QEE+LRE E+K++++EEK
Sbjct: 235 PLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEK 294
Query: 464 MQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQE 523
M QEE+++ QE K++EQEEK WRQEK L+++EK ++EK R+++++ EQEE+MQEQE
Sbjct: 295 MWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQE 354
Query: 524 EKMQRQEEKMREQEVRLWQQEEKMQEQE--VRLQE--LEERLGKLGQKAELLGGAGRESG 579
EKM QEEKMREQE ++W+QEE++ EQE +R QE + ++ ++ ++ E L RE
Sbjct: 355 EKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERL----REK- 409
Query: 580 SQRLPTLTPILQVELKSQEAQSLQQQQDHYR 610
+R+ + + K +E + +Q+Q+ R
Sbjct: 410 EERMREQEKMWEQVEKMREEKKMQEQEKKTR 440
Score = 40.8 bits (94), Expect = 0.004
Identities = 36/201 (17%), Positives = 92/201 (45%), Gaps = 14/201 (6%)
Query: 449 KLREVEEKMQEEEEKMQEQEEKIQRQEEKIQ-EQEEKTWRQEKLLKQEEKIWEQEEKMWR 507
+L+ + +K E++ ++ + + E T E+L K+ ++ +EK+
Sbjct: 180 ELQRALSAVSTRHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAEL---QEKLPL 236
Query: 508 QEEKMWEQEEKMQEQEEKMQRQEEKMREQEVR-----LWQQEEKMQEQEVRLQELEERLG 562
E + E + ++E + K++R + + + + +W+QEE+++EQE ++++ EE++
Sbjct: 237 AESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMW 296
Query: 563 KLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQQYVAAYQQ 622
+ ++ G RE + + + E + +E + ++Q R +Q ++
Sbjct: 297 RQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEK 356
Query: 623 LASGKEALPSCSSRKLRAKRW 643
+ +E + R+ K W
Sbjct: 357 MWEQEEKM-----REQEEKMW 372
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 319 bits (818), Expect = 4e-87
Identities = 178/420 (42%), Positives = 292/420 (69%), Gaps = 50/420 (11%)
Query: 211 ITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKE 270
IT+EELKEKNAELQE+L+LVE+EKSEIQL++K+LKRKLE ++ LPQ+ E + +E
Sbjct: 4 ITNEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVRE 63
Query: 271 LQSVSAKLQAQVEENELWNLLNQQ----------------------------------QE 296
+ + + QV E E + +Q QE
Sbjct: 64 QEGQVREQEGQVREQE--GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 121
Query: 297 EKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIR 356
++ QE +++EQE ++ EQE ++REQE ++ QE ++ EQE ++REQE ++ QE ++R
Sbjct: 122 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 181
Query: 357 EQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEE---KRQEKMWRQEK 413
EQE ++REQE +M QE ++ EQ+E++ EQEE+M +QEE++ EQEE K++E+M QE+
Sbjct: 182 EQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEE 241
Query: 414 KMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKL------REVEEKMQEEEEKMQEQ 467
++++Q+E++++QEE+M +QEE++RE EE M++QEE++ E EE+ E+EE+M+EQ
Sbjct: 242 QVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQ 301
Query: 468 EEKIQRQEEKIQEQEEKTWRQEKLL-KQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKM 526
EE+++ QEE+++EQEE+ QE+ + KQEE++WEQ+E+MW Q+E+MW+QEE+M EQEE+M
Sbjct: 302 EEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQM 361
Query: 527 QRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLG----KLGQKAELLGGAGRESGSQR 582
Q+QEE++R+QE ++ +QEE+M++QE ++++ EE++G ++G++ E + + G Q+
Sbjct: 362 QKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQK 421
Score = 266 bits (681), Expect = 3e-71
Identities = 152/398 (38%), Positives = 279/398 (70%), Gaps = 38/398 (9%)
Query: 215 ELKEKNAELQEK---LRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQV-EADRLGKE 270
+++E+ +++E+ +R E + E + V++ + ++ + + +Q+ QV E + +E
Sbjct: 67 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 126
Query: 271 LQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQ 330
+ + + QV E E ++QE ++ QE +++EQE ++ EQE ++REQE ++ Q
Sbjct: 127 QEGQVREQEGQVREQEGQV---REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 183
Query: 331 EEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEM 390
E ++ EQE ++ EQE +M QEE++ EQEE++++QEE+M QEE++R+Q+E++ EQEE++
Sbjct: 184 EGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQV 243
Query: 391 WRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKL 450
+QEE++++QE E+M +QE++MREQ+E++REQEE+M +Q+E+ E EE +QEE++
Sbjct: 244 QKQEEQVQKQE----EQMRKQEEQMREQEEQMREQEEQMLKQKEQ-TEQEEQTGEQEEQM 298
Query: 451 REVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEE 510
RE EE+M+E+EE+M+EQEE+++ QEE++ +QEE+ W +Q+E++WEQ+E+MW+QEE
Sbjct: 299 REQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMW------EQKEQMWEQKEQMWKQEE 352
Query: 511 KMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAEL 570
+M EQEE+MQ+QEE++++QEE+MR+QE ++ +QEE+M++QE ++ E +E++G+ QK ++
Sbjct: 353 QMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGE--QKEQM 410
Query: 571 LGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDH 608
RE Q E ++ + +++Q++H
Sbjct: 411 -----RE-------------QEEQMGEQKEQMRKQEEH 430
Score = 257 bits (657), Expect = 2e-68
Identities = 143/352 (40%), Positives = 259/352 (73%), Gaps = 10/352 (2%)
Query: 215 ELKEKNAELQEK---LRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQV-EADRLGKE 270
+++E+ +++E+ +R E + E + V++ + ++ + + +Q+ QV E + +E
Sbjct: 88 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 147
Query: 271 LQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQ 330
+ + + QV E E ++QE ++ QE +++EQE ++ EQE ++ EQE +M Q
Sbjct: 148 QEGQVREQEGQVREQEGQV---REQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQ 204
Query: 331 EEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEM 390
EE+M EQEE++++QE++M QEE++R+QEE++ EQEE++ +QEE++++Q+E++++QEE+M
Sbjct: 205 EEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQM 264
Query: 391 WRQEEKIREQEEK--RQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEE 448
QEE++REQEE+ +Q++ QE++ EQ+E++REQEE+M QEE++RE EE M++QEE
Sbjct: 265 REQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEE 324
Query: 449 KLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQ-EKLLKQEEKIWEQEEKMWR 507
++ + EE+M E++E+M EQ+E++ +QEE++ EQEE+ +Q E++ KQEE++ +QEE+M +
Sbjct: 325 QMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRK 384
Query: 508 QEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEE 559
QEE+M +QEE+M EQ+E+M Q+E+MREQE ++ +Q+E+M++QE + E +E
Sbjct: 385 QEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
Score = 201 bits (512), Expect = 1e-51
Identities = 117/341 (34%), Positives = 215/341 (63%), Gaps = 18/341 (5%)
Query: 290 LLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMW 349
+ N++ +EK +E++Q E + E +L I+E + K+ + + QE ++REQE ++
Sbjct: 4 ITNEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPL-PQEGQVREQEGQVR 62
Query: 350 RQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMW 409
QE ++REQE ++REQE ++ QE ++REQ+ +++EQE ++ QE ++REQE + +E
Sbjct: 63 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE--- 119
Query: 410 RQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEE 469
QE ++REQ+ ++REQE ++ QE ++RE E +++QE ++RE E +++E+E +++EQE
Sbjct: 120 -QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 178
Query: 470 KIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQ 529
+++ QE +++EQE + + EQE +M QEE+M EQEE+MQ+QEE+M Q
Sbjct: 179 QVREQEGQVREQEGQ-------------MGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQ 225
Query: 530 EEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPI 589
EE+MR+QE ++ +QEE++Q+QE ++Q+ EE++ K ++ RE Q L
Sbjct: 226 EEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQT 285
Query: 590 LQVELKSQEAQSLQQQQDHYRGHLQQYVAAYQQLASGKEAL 630
Q E ++ + +++Q++ R +Q +Q+ +E +
Sbjct: 286 EQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQM 326
Score = 172 bits (437), Expect = 7e-43
Identities = 92/236 (38%), Positives = 163/236 (69%), Gaps = 4/236 (1%)
Query: 213 DEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQ 272
+E++ E+ ++Q++ + ++ +++ + + + E+ Q Q Q Q E R +E
Sbjct: 205 EEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQM 264
Query: 273 SVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEE 332
+ + EE L +QEE+ QEE+++EQEE+M EQE ++REQEE+M QEE
Sbjct: 265 REQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEE 324
Query: 333 KMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWR 392
+M +QEE++ EQ+++MW Q+E++ +QEE++ EQEE+M +QEE++R+Q+E++++QEE+M +
Sbjct: 325 QMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRK 384
Query: 393 QEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEE 448
QEE++R+QE E+M Q+++M EQ E++REQEE+M Q+E++R+ EE M +Q+E
Sbjct: 385 QEEQMRKQE----EQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
Score = 162 bits (409), Expect = 1e-39
Identities = 108/421 (25%), Positives = 243/421 (57%), Gaps = 23/421 (5%)
Query: 24 VLSDEDSDLDFHINKLEQQ---SKVRNKGHGKPREKS-IADEKFFQLSEMEAYLEN---- 75
++ E S++ HI +L+++ K+ G+ RE+ E+ Q+ E E +
Sbjct: 22 LVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 81
Query: 76 -RKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSS 134
R++ G R E E+ ++ + ++ + + E V++ +V+
Sbjct: 82 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 141
Query: 135 ---FKKRQEKMNEKNYTFRKRV-VIKKPWLRLGEVTAQKRPENSLL--EETLHFDHAVRM 188
++++ ++ E+ R++ +++ ++ E Q R + + +E + +M
Sbjct: 142 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQM 201
Query: 189 GTYIEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKL 248
G E++ ++ + + + + +E+++++ ++ E+ V+ ++ ++Q + ++++
Sbjct: 202 GEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQE 261
Query: 249 ERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQ--QQEEKMWRQEEKI 306
E Q+ ++Q++ + +++ K+ + + Q +E ++ Q +QEE+M QEE++
Sbjct: 262 E--QMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQM 319
Query: 307 QEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQE 366
+EQEE+M +QE ++ EQ+E+MW Q+E+M +QEE++ EQE++M +QEE++R+QEE++R+QE
Sbjct: 320 REQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQE 379
Query: 367 EKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQE 426
E+M +QEE++R+Q+E++ EQ+E+M Q+E++REQE E+M Q+++MR+Q+E + EQ+
Sbjct: 380 EQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQE----EQMGEQKEQMRKQEEHMGEQK 435
Query: 427 E 427
E
Sbjct: 436 E 436
Score = 114 bits (286), Expect = 2e-25
Identities = 78/275 (28%), Positives = 165/275 (60%), Gaps = 18/275 (6%)
Query: 377 REQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIR-EQEEEMWRQEEK 435
R +E+++E+ E+ QEE + EK + ++ +E K + + +KI QE ++ QE +
Sbjct: 3 RITNEELKEKNAEL--QEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQ 60
Query: 436 IRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQE-KLLKQ 494
+RE E +++QE ++RE E +++E+E +++EQE +++ QE +++EQE + QE ++ +Q
Sbjct: 61 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 120
Query: 495 EEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRL 554
E ++ EQE ++ QE ++ EQE +++EQE +++ QE ++REQE ++ +QE +++EQE ++
Sbjct: 121 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 180
Query: 555 QELE----ERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYR 610
+E E E+ G++G++ +G + G Q + +++ QE Q + +Q++ R
Sbjct: 181 REQEGQVREQEGQMGEQEGQMGEQEEQMGEQ---------EEQMQKQEEQ-MGEQEEQMR 230
Query: 611 GHLQQYVAAYQQLASGKEALPSCSSRKLRAKRWLR 645
+Q +Q+ +E + + + + +R
Sbjct: 231 KQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMR 265
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 231 bits (589), Expect = 2e-60
Identities = 148/420 (35%), Positives = 247/420 (58%), Gaps = 58/420 (13%)
Query: 190 TYIEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKL- 248
T +E L + L++ L ++ +L E L + E +K EI L V+ L R L
Sbjct: 82 TTLEDLESQYQELAVALDSSSAIISQLTENINSLVRTSK--EEKKHEIHL-VQKLGRSLF 138
Query: 249 ----ERAQLLLPQ--------QQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQ--- 293
+ A+ L P+ +QLQ E + L KEL+SV +LQA+VE N++ +LLN+
Sbjct: 139 KLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQE 198
Query: 294 ----QQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMW 349
+QEE++ QEE+++EQEE++CEQE ++REQEE++ QEE++ EQEE++RE E+++
Sbjct: 199 ERLREQEERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQEERLREHEERLC 258
Query: 350 RQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMW 409
QEE++ EQEE++REQEE++ QEE++ EQ+E+++EQEE + QEE++REQEE
Sbjct: 259 EQEERLCEQEERLREQEERLHEQEERLCEQEERLREQEERLCEQEERLREQEE------- 311
Query: 410 RQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEE 469
++ EQ+E++REQEE + QE+ + QE L EV EK+ E+E + +EQE
Sbjct: 312 ----RLCEQEERLREQEERLCEQEK--------LPGQERLLEEV-EKLLEQERRQEEQER 358
Query: 470 KIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQ 529
++R E++ E+ E+ QE+L +Q+E++W+QE ++ E+++E E ++
Sbjct: 359 LLER--ERLLEEVEELLEQERLRQQDERLWQQE---------TLQELERLRELERMLELG 407
Query: 530 EEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPI 589
E + EQ E++ + +LE+++ +L + GGA GS+ P+
Sbjct: 408 WEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELKKS----GGAEEPRGSESAAAARPV 463
Score = 155 bits (392), Expect = 1e-37
Identities = 100/333 (30%), Positives = 182/333 (54%), Gaps = 62/333 (18%)
Query: 175 LLEETLHFDHAVR-MGTYIEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESE 233
L +ET H + +G ++ + LSL R E +E+ E +E+LR E
Sbjct: 162 LQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQEER 221
Query: 234 KSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQ 293
E +++L+ + +RL +
Sbjct: 222 LCE-------------------QEERLREQEERL-------------------------R 237
Query: 294 QQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEE 353
+QEE++ QEE+++E EE++CEQE ++ EQEE++ QEE++HEQEE++ EQE+++ QEE
Sbjct: 238 EQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQEE 297
Query: 354 KIREQEEKIREQEEKMWRQEEKIREQDEKIQEQE-----EEMWRQEEKIREQE--EKRQE 406
++ EQEE++REQEE++ QEE++REQ+E++ EQE E + + EK+ EQE ++ QE
Sbjct: 298 RLCEQEERLREQEERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQE 357
Query: 407 KMWRQEKKMRE-----QDEKIREQEEEMWRQE-----EKIRELEEMMQDQEEKLREVEEK 456
++ +E+ + E + E++R+Q+E +W+QE E++RELE M++ E L E +
Sbjct: 358 RLLERERLLEEVEELLEQERLRQQDERLWQQETLQELERLRELERMLELGWEALYEQRAE 417
Query: 457 MQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQE 489
+ E++ + + + E++++E ++ +E
Sbjct: 418 PRSGFEELNNENKSTLQLEQQVKELKKSGGAEE 450
>gi|239752551 PREDICTED: hypothetical protein [Homo sapiens]
Length = 238
Score = 222 bits (566), Expect = 7e-58
Identities = 112/177 (63%), Positives = 149/177 (84%), Gaps = 5/177 (2%)
Query: 309 QEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEK 368
+EE+M E+E K+RE+EE M QEEKM EQEEK+REQE+KMW QEEK++EQEEK+ EQEEK
Sbjct: 3 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 62
Query: 369 MWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEK-RQEKMWRQEKKMREQDEKIREQEE 427
MW QEEK+ EQ +++ EQ+E+MW Q+E++RE+EE+ R++KMW+Q +KMR EK + QEE
Sbjct: 63 MWEQEEKMWEQ-QRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMR---EKKKTQEE 118
Query: 428 EMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEK 484
+M QEEK++E EEMM +QEEK++E EEKM E+EEKM+EQEEK++ QEEK+Q QEEK
Sbjct: 119 KMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEK 175
Score = 219 bits (557), Expect = 8e-57
Identities = 114/197 (57%), Positives = 153/197 (77%), Gaps = 20/197 (10%)
Query: 329 RQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEE 388
R+EE+M E+E+K+RE+E+ M QEEK++EQEEK+REQEEKMW QEEK++EQ+EK+ EQEE
Sbjct: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
Query: 389 EMWRQEEKIREQEE--KRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQ 446
+MW QEEK+ EQ+ +++EKMW Q++++RE++E++REQ +MW+Q EK+R
Sbjct: 62 KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQ--KMWQQVEKMR--------- 110
Query: 447 EEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMW 506
EK + EEKMQE+EEKMQEQEE + QEEK+QEQEEK W +QEEK+ EQEEKM
Sbjct: 111 -EKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMW------EQEEKMREQEEKMR 163
Query: 507 RQEEKMWEQEEKMQEQE 523
QEEKM QEEKM++ E
Sbjct: 164 EQEEKMQGQEEKMRDVE 180
Score = 215 bits (548), Expect = 9e-56
Identities = 108/183 (59%), Positives = 150/183 (81%), Gaps = 10/183 (5%)
Query: 293 QQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQE 352
+++E+KM +EE ++EQEEKM EQE K+REQEEKMW QEEKM EQEEK+ EQE+KMW QE
Sbjct: 8 REREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE 67
Query: 353 EKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQE 412
EK+ EQ +++ EQ+EKMW Q+E++RE++E+++EQ +MW+Q EK+RE+++ QE
Sbjct: 68 EKMWEQ-QRLPEQKEKMWEQDERLREKEERMREQ--KMWQQVEKMREKKK-------TQE 117
Query: 413 KKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQ 472
+KM+EQ+EK++EQEE MW QEEK++E EE M +QEEK+RE EEKM+E+EEKMQ QEEK++
Sbjct: 118 EKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMR 177
Query: 473 RQE 475
E
Sbjct: 178 DVE 180
Score = 209 bits (532), Expect = 6e-54
Identities = 117/217 (53%), Positives = 157/217 (72%), Gaps = 27/217 (12%)
Query: 350 RQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMW 409
R+EE++RE+E+K+RE+EE M QEEK++EQ+EK++EQEE+MW QEEK++EQ +EKMW
Sbjct: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQ----EEKMW 57
Query: 410 RQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEE-----EKM 464
EQ+EK+ EQEE+MW Q+ ++ E +E M +Q+E+LRE EE+M+E++ EKM
Sbjct: 58 -------EQEEKMWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQKMWQQVEKM 109
Query: 465 QE----QEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQ 520
+E QEEK+Q QEEK+QEQEE W +QEEK+ EQEEKMW QEEKM EQEEKM+
Sbjct: 110 REKKKTQEEKMQEQEEKMQEQEEMMW------EQEEKMQEQEEKMWEQEEKMREQEEKMR 163
Query: 521 EQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQEL 557
EQEEKMQ QEEKMR+ E + E + QE+
Sbjct: 164 EQEEKMQGQEEKMRDVEPAGGEAGEGSPQDNPTAQEI 200
Score = 198 bits (504), Expect = 1e-50
Identities = 115/235 (48%), Positives = 159/235 (67%), Gaps = 30/235 (12%)
Query: 371 RQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMW 430
R+EE++RE+++K++E+EE M QEEK++EQEEK MREQ+EK+ EQEE+M
Sbjct: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEK-----------MREQEEKMWEQEEKMQ 50
Query: 431 RQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQ-- 488
QEEK+ E EE M +QEEK+ E ++++ E++EKM EQ+E+++ +EE+++EQ K W+Q
Sbjct: 51 EQEEKMWEQEEKMWEQEEKMWE-QQRLPEQKEKMWEQDERLREKEERMREQ--KMWQQVE 107
Query: 489 ---EKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEE 545
EK QEEK+ EQEEKM QEE MWEQEEKMQEQEEKM QEEKMREQE ++ +QEE
Sbjct: 108 KMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEE 167
Query: 546 KMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQ 600
KMQ QE +++++E GG E Q PT I+Q+ + AQ
Sbjct: 168 KMQGQEEKMRDVEP-----------AGGEAGEGSPQDNPTAQEIMQLFCGMKNAQ 211
Score = 191 bits (486), Expect = 1e-48
Identities = 103/175 (58%), Positives = 133/175 (76%), Gaps = 27/175 (15%)
Query: 283 EENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEK-- 340
EE E+ ++QEEKM QEEK++EQEEKM EQE K++EQEEKMW QEEKM EQEEK
Sbjct: 16 EEEEMM----REQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMW 71
Query: 341 ----IREQEDKMWRQEEKIREQEEKIREQEEKMWRQ-----------EEKIREQDEKIQE 385
+ EQ++KMW Q+E++RE+EE++REQ KMW+Q EEK++EQ+EK+QE
Sbjct: 72 EQQRLPEQKEKMWEQDERLREKEERMREQ--KMWQQVEKMREKKKTQEEKMQEQEEKMQE 129
Query: 386 QEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELE 440
QEE MW QEEK++EQEEK MW QE+KMREQ+EK+REQEE+M QEEK+R++E
Sbjct: 130 QEEMMWEQEEKMQEQEEK----MWEQEEKMREQEEKMREQEEKMQGQEEKMRDVE 180
Score = 169 bits (428), Expect = 7e-42
Identities = 94/192 (48%), Positives = 139/192 (72%), Gaps = 18/192 (9%)
Query: 241 VKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLN--QQQEEK 298
+++ +R ER + + ++++ E + +++Q K++ Q E ++W Q+QEEK
Sbjct: 1 MREEERMREREKKMREEEEMMREQE---EKMQEQEEKMREQ--EEKMWEQEEKMQEQEEK 55
Query: 299 MWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIRE- 357
MW QEEK+ EQEEKM EQ+ ++ EQ+EKMW Q+E++ E+EE++REQ KMW+Q EK+RE
Sbjct: 56 MWEQEEKMWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQ--KMWQQVEKMREK 112
Query: 358 ---QEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKK 414
QEEK++EQEEKM QEE + EQ+EK+QEQEE+MW QEEK+REQEEK +E QE+K
Sbjct: 113 KKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMRE----QEEK 168
Query: 415 MREQDEKIREQE 426
M+ Q+EK+R+ E
Sbjct: 169 MQGQEEKMRDVE 180
Score = 145 bits (365), Expect = 1e-34
Identities = 80/184 (43%), Positives = 125/184 (67%), Gaps = 21/184 (11%)
Query: 234 KSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSV-SAKLQAQVEENELWNLLN 292
+ E ++ ++ K + E + ++++Q + +++ ++ + + + + Q +E ++W
Sbjct: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMW---- 57
Query: 293 QQQEEKMWRQEEK------IQEQEEKMCEQELKIREQEE-----KMWRQEEKMHE----Q 337
+QEEKMW QEEK + EQ+EKM EQ+ ++RE+EE KMW+Q EKM E Q
Sbjct: 58 -EQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQ 116
Query: 338 EEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKI 397
EEK++EQE+KM QEE + EQEEK++EQEEKMW QEEK+REQ+EK++EQEE+M QEEK+
Sbjct: 117 EEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKM 176
Query: 398 REQE 401
R+ E
Sbjct: 177 RDVE 180
Score = 111 bits (278), Expect = 2e-24
Identities = 68/144 (47%), Positives = 94/144 (65%), Gaps = 23/144 (15%)
Query: 473 RQEEKIQEQEEKTWRQEKLLK-QEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEE 531
R+EE+++E+E+K +E++++ QEEK+ EQEEKM QEEKMWEQEEKMQEQEEKM QEE
Sbjct: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
Query: 532 KMREQEVRLWQQE------EKMQEQEVRLQELEERL--GKLGQKAELLGGAGRESGSQRL 583
KM EQE ++W+Q+ EKM EQ+ RL+E EER+ K+ Q+ E + RE +
Sbjct: 62 KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKM----REKKKTQ- 116
Query: 584 PTLTPILQVELKSQEAQSLQQQQD 607
E K QE + Q+Q+
Sbjct: 117 ---------EEKMQEQEEKMQEQE 131
Score = 100 bits (250), Expect = 3e-21
Identities = 57/129 (44%), Positives = 83/129 (64%), Gaps = 4/129 (3%)
Query: 478 IQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQE 537
++E+E R++K+ ++EE + EQEEKM QEEKM EQEEKM EQEEKMQ QEEKM EQE
Sbjct: 1 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60
Query: 538 VRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQ 597
++W+QEEKM EQ Q L E+ K+ ++ E L Q++ ++ + K+Q
Sbjct: 61 EKMWEQEEKMWEQ----QRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQ 116
Query: 598 EAQSLQQQQ 606
E + +Q++
Sbjct: 117 EEKMQEQEE 125
Score = 95.5 bits (236), Expect = 1e-19
Identities = 61/182 (33%), Positives = 102/182 (56%), Gaps = 5/182 (2%)
Query: 164 EVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDALSLELYRNTITDEELKEKNAEL 223
E ++R + EE + + +M EK+ ++ + +++ +E +EK E
Sbjct: 4 EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEE----KMWEQEEKMQEQEEKMWEQ 59
Query: 224 QEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVE 283
+EK+ + EK Q + + K K+ L +++ ++ ++ ++++ + K + Q E
Sbjct: 60 EEKM-WEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEE 118
Query: 284 ENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIRE 343
+ + Q+QEE MW QEEK+QEQEEKM EQE K+REQEEKM QEEKM QEEK+R+
Sbjct: 119 KMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRD 178
Query: 344 QE 345
E
Sbjct: 179 VE 180
>gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo
sapiens]
Length = 479
Score = 184 bits (467), Expect = 2e-46
Identities = 123/337 (36%), Positives = 207/337 (61%), Gaps = 35/337 (10%)
Query: 190 TYIEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKL- 248
T ++ L + L++ L ++ +L E L + E +K EI L V+ L R L
Sbjct: 82 TTLQDLESQYQELAVALDSSSAIISQLTENINSLVRTSK--EEKKHEIHL-VQKLGRSLF 138
Query: 249 ----ERAQLLLPQ--------QQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQE 296
+ A+ L P+ +QLQ E + L KEL+SV +LQA+VE N++ +LLN++QE
Sbjct: 139 KLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQE 198
Query: 297 EKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIR 356
E++ QEE++ EQEE++ EQE ++ EQEE++ QEE++ EQEE++REQE+++ QEE++
Sbjct: 199 ERLREQEERLHEQEERLHEQEERLCEQEERLCEQEERLREQEERLREQEERLHEQEERLC 258
Query: 357 EQEEKIREQEEKMWRQE-----EKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQ 411
EQEE++ EQEE++ QE E++ E+ EK+ EQE RQEE+ R E +E++ +
Sbjct: 259 EQEERLCEQEERLCEQEKLPGQERLLEEVEKLLEQER---RQEEQERLLE---RERLLDE 312
Query: 412 EKKMREQDEKIREQEEEMWRQE-----EKIRELEEMMQDQEEKLREVEEKMQEEEEKMQE 466
+++ EQ E++R+Q+E +W+QE E++RELE + + E+LRE+E ++ E + E
Sbjct: 313 VEELLEQ-ERLRQQDERLWQQETLRELERLRELERLR--ELERLRELERMLELGWEALYE 369
Query: 467 QEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEE 503
Q + + E++ + + T + E+ +K+ EK EE
Sbjct: 370 QRAEPRSGFEELNNENKSTLQLEQQVKELEKSGGAEE 406
Score = 143 bits (361), Expect = 4e-34
Identities = 97/271 (35%), Positives = 162/271 (59%), Gaps = 26/271 (9%)
Query: 330 QEEKMHEQEEKIREQEDKMWRQEEKIREQE-EKIREQEEKMWRQEEKIREQDEKIQEQEE 388
+EEK HE K+ R K++ Q E + + + E+++++ ++++ E
Sbjct: 120 KEEKKHEIH-----LVQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELE 174
Query: 389 EMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEE 448
+ RQ + E + RQE+++REQ+E++ EQEE + QEE++ E EE + +QEE
Sbjct: 175 SVGRQLQAEVENNQMLSLLNRRQEERLREQEERLHEQEERLHEQEERLCEQEERLCEQEE 234
Query: 449 KLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQE------EKIWEQE 502
+LRE EE+++E+EE++ EQEE++ QEE++ EQEE+ QEKL QE EK+ EQE
Sbjct: 235 RLREQEERLREQEERLHEQEERLCEQEERLCEQEERLCEQEKLPGQERLLEEVEKLLEQE 294
Query: 503 EKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQE-----EKMQEQEVRLQEL 557
+ ++E++ E+E + E EE ++ +E++R+Q+ RLWQQE E+++E E RL+EL
Sbjct: 295 RRQ-EEQERLLERERLLDEVEELLE--QERLRQQDERLWQQETLRELERLRELE-RLREL 350
Query: 558 E-----ERLGKLGQKAELLGGAGRESGSQRL 583
E ER+ +LG +A A SG + L
Sbjct: 351 ERLRELERMLELGWEALYEQRAEPRSGFEEL 381
Score = 65.9 bits (159), Expect = 1e-10
Identities = 55/236 (23%), Positives = 122/236 (51%), Gaps = 17/236 (7%)
Query: 168 QKRPENSLLEETLHFDHAVRMGTYIEKLTKERDALSLELYRNTITDEELKEKNAELQEKL 227
Q EN+ + L+ R+ E+L ++ + L + R +E L E+ L+E+
Sbjct: 181 QAEVENNQMLSLLNRRQEERLREQEERLHEQEERLHEQEERLCEQEERLCEQEERLREQE 240
Query: 228 RLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRL-GKELQSVSAKLQAQVEENE 286
+ ++ + + +R E+ + L Q++ E ++L G+E +L +VE +
Sbjct: 241 ERLREQEERLH---EQEERLCEQEERLCEQEERLCEQEKLPGQE------RLLEEVE--K 289
Query: 287 LWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQED 346
L +Q+E++ + E++ ++ E++ EQE ++R+Q+E++W+QE + E++RE E
Sbjct: 290 LLEQERRQEEQERLLERERLLDEVEELLEQE-RLRQQDERLWQQETL--RELERLRELE- 345
Query: 347 KMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEE 402
R+ E++RE E + E ++ Q + R E++ + + + E++++E E+
Sbjct: 346 -RLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELEK 400
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 180 bits (457), Expect = 3e-45
Identities = 147/560 (26%), Positives = 298/560 (53%), Gaps = 64/560 (11%)
Query: 40 EQQSKVRNKGHGKPREKSIADEKFFQL-SEMEA-----YLENRKRRGTKRWDEDDDLEES 93
EQ+ + + R KS + +QL SE +A Y RK+ G +R E ++
Sbjct: 682 EQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRR 741
Query: 94 EDSKQCKESLKRVTFTLPDDEAIED---AGVSHVKKNSDEVKSSFKKRQEKMNEKNYTFR 150
+S+ + +R ++E D + K + S + + E+
Sbjct: 742 RESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAE 801
Query: 151 KRVVIKKPWLRLGEVTAQKRPENSLLEETLHF---DHAVRMGTYIEKLTKERDALSLELY 207
+R ++ +L E Q+R + E+ L F + ++ ++L +E D L +
Sbjct: 802 ERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQED-- 859
Query: 208 RNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRL 267
E + + +K R E+ + + + K L+ QL QQ LQ E + L
Sbjct: 860 -----QERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQE-QLRKEQQLLQEEEEEL 913
Query: 268 GKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMC--EQELKIREQEE 325
Q EE E +Q++E+ +R+EE++Q++EE++ E+E + R++ E
Sbjct: 914 -------------QREEREK---RRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERE 957
Query: 326 KMWRQEEKMHEQEEKIREQEDKMWRQEE---KIREQEEKIREQEEKMWRQEEKIREQDEK 382
+ +R+++K+ ++EE++ +E + R++E K RE+EE +E+E+ + + EK R Q+ +
Sbjct: 958 RQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWE 1017
Query: 383 IQEQEEEMWRQEEK--IREQEEKR----QEKMWRQEKKMREQDEKIREQEEEMWRQEE-- 434
Q ++++ +QEE+ +RE+ EKR +E+ +R+E+++++++E++ +E E R++E
Sbjct: 1018 RQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELE 1077
Query: 435 -KIRELEEMMQDQEEKLREVEEK--MQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQ--E 489
+ R+ EE+ Q++E+ LRE EK QE E + +E+EE Q +E+ ++E+ EK RQ E
Sbjct: 1078 RQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELE 1137
Query: 490 KLLKQEEKIWEQEEKMWRQE---------EKMWEQEEKMQEQEEKMQRQE-EKMREQEVR 539
+ ++EE++ ++EE++ R+E E+ + +EE++Q++EE++ R+E EK R++ R
Sbjct: 1138 RQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERER 1197
Query: 540 LWQQEEKMQEQEVRLQELEE 559
+++EE++Q Q+ + + +E
Sbjct: 1198 QYREEEELQRQKRKQRYRDE 1217
Score = 178 bits (451), Expect = 2e-44
Identities = 164/581 (28%), Positives = 310/581 (53%), Gaps = 86/581 (14%)
Query: 60 DEKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDE---AI 116
D++ F+ + + E +RR KR +++ +L E E+ + +E L++ D+E
Sbjct: 118 DQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQR 177
Query: 117 EDAGVSHVKKNSDEVKSSFK--KRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENS 174
++ ++ +E S K + +E +E+ R+ + +++ + ++R +
Sbjct: 178 QEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRV 237
Query: 175 LLEETLHFDHAVRMGTYIEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEK 234
EE EK ++R+ + + +E+L+E+ + Q +L ++
Sbjct: 238 FQEEE-------------EKEWRKRETVLRK------EEEKLQEEEPQRQREL-----QE 273
Query: 235 SEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQ 294
E QL RKLER +L +Q+ + + RL +E Q L+ + EE +Q
Sbjct: 274 EEEQL------RKLERQELRRERQEEEQQQQRLRREQQ-----LRRKQEEER-----REQ 317
Query: 295 QEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQ----EDKMWR 350
QEE+ R++++ +EQ+E+ EQ+L+ REQEE+ R+++ EQEE+ REQ E + R
Sbjct: 318 QEER--REQQERREQQEERREQQLR-REQEER--REQQLRREQEEERREQQLRREQEEER 372
Query: 351 QEEKIREQEEKIREQE---EKMWRQEEKIREQDEKIQEQ----EEEMWRQEEKIREQEEK 403
+E+++R +++ REQ+ E+ R+E+++R + + +EQ E+++ R+++ REQEE+
Sbjct: 373 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEE 432
Query: 404 RQEKMWRQEKK----MREQDEK----IREQEEEMWRQEEKIRELEEMMQDQEE------- 448
R E+ QE++ REQ+E+ RE+E E QE R +++ +DQEE
Sbjct: 433 RHEQKHEQERREQRLKREQEERRDWLKREEETERHEQE---RRKQQLKRDQEEERRERWL 489
Query: 449 KLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQ 508
KL E E + Q+E + Q + E+ +R+E++++ QEE+ Q++L +++ EQEE R+
Sbjct: 490 KLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEE---RR 546
Query: 509 EEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKA 568
E+ + +EEK EQE + QR + + E+ +L ++EE+ ++Q ++ +E EERL + ++
Sbjct: 547 EQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLK-REQEERLEQRLKRE 605
Query: 569 ELLGGAGRESGSQRLPTLTP---ILQVELKSQEAQSLQQQQ 606
E+ E QRL P Q LKS+E + +QQQ
Sbjct: 606 EVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQ 646
Score = 175 bits (443), Expect = 1e-43
Identities = 167/652 (25%), Positives = 341/652 (52%), Gaps = 95/652 (14%)
Query: 38 KLEQQSKVRNKGHGKPREKSIADEKFFQLSEMEAYLE--NRKRRGTKRWDEDDDLEESED 95
+LE++ R + + +E+ +A+ + + SE + LE +R+RR + W + + +E E+
Sbjct: 128 QLEEEPGQRRRQKRQEQERELAEGE--EQSEKQERLEQRDRQRRDEELWRQRQEWQEREE 185
Query: 96 SKQCKESLKRV----TFTLPDDEAIEDAGVSHVK-KNSDEVKSSFKKRQEKM--NEKNYT 148
+ +E L+ T PD+E + + ++ K +E + ++RQ+++ E+
Sbjct: 186 RRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKE 245
Query: 149 FRKR-VVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDALSLELY 207
+RKR V++K +L E Q++ E EE L + ++ +++ L E
Sbjct: 246 WRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQ 305
Query: 208 RNTITDEELKEKNAEL--QEKLRLVESEKSEIQLN-------VKDLKRKLE---RAQLLL 255
+EE +E+ E Q++ R + E+ E QL + L+R+ E R Q L
Sbjct: 306 LRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLR 365
Query: 256 PQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCE 315
+Q+ + +L +E Q + + Q+ + Q + E+ R+E++++ +++ E
Sbjct: 366 REQEEERREQQLRREQQ---LRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 422
Query: 316 QELKIREQEEKMWRQEEKMHEQEEKI-REQEDKM-W--------RQEEKIREQEEKIREQ 365
Q+L+ REQEE+ Q+ + +E+++ REQE++ W R E++ R+Q+ K ++
Sbjct: 423 QQLR-REQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQE 481
Query: 366 EEKMWR----QEEKIREQDEKIQEQ---------EEEMWRQEEK-------------IRE 399
EE+ R +EE+ REQ E+ ++Q E+ + RQEE+ RE
Sbjct: 482 EERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRRE 541
Query: 400 QEEKRQEKMWRQEKKMREQDEK----IREQEE---EMWRQEEKIRELEEMMQDQEEKLRE 452
QEE+R++ + R+E+K EQ+ + REQEE ++ ++EE+ R+ + + ++QEE+L
Sbjct: 542 QEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQ-QRLKREQEERL-- 598
Query: 453 VEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKM 512
E++++ EE + EQEE R+E++++ +E + R+++LLK EE+ +++++ R++++
Sbjct: 599 -EQRLKREEVERLEQEE---RREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQER 654
Query: 513 WEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKL-------- 564
EQ K +E+EE+++++ ++ E+E R +QE +EQE + ++ R+ K
Sbjct: 655 REQRLKREEEEERLEQRLKREHEEERR--EQELAEEEQEQARERIKSRIPKWQWQLESEA 712
Query: 565 -GQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQQ 615
+++++ ++ G +R + E K + +S Q Q+ R H QQ
Sbjct: 713 DARQSKVYSRPRKQEGQRRRQ------EQEEKRRRRESELQWQEEERAHRQQ 758
Score = 171 bits (434), Expect = 1e-42
Identities = 156/533 (29%), Positives = 298/533 (55%), Gaps = 77/533 (14%)
Query: 129 DEVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRM 188
D +S + R+++ +++ + R R + ++P G+ QKR E E +
Sbjct: 104 DGKESLLQDRRQEEDQRRFEPRDRQLEEEP----GQRRRQKRQEQE--RELAEGEEQSEK 157
Query: 189 GTYIEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRK- 247
+E+ ++R EL+R +E +E+ AE +E+L+ + ++E + + L+R+
Sbjct: 158 QERLEQ--RDRQRRDEELWRQRQEWQEREERRAE-EEQLQSCKGHETEEFPDEEQLRRRE 214
Query: 248 ---LERAQLLLPQQQLQVEADRLGKE--------LQSVSAKLQAQVEENELWNLLNQQQE 296
L R QQQ + DR+ +E ++V K + +++E E Q+E
Sbjct: 215 LLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEE 274
Query: 297 E----KMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQE 352
E K+ RQE + + QEE+ +Q+ ++R +++ +QEE+ EQ+E+ REQ+++ +QE
Sbjct: 275 EEQLRKLERQELRRERQEEE--QQQQRLRREQQLRRKQEEERREQQEERREQQERREQQE 332
Query: 353 EKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQ----EEEMWRQEEKIREQEEKRQEKM 408
E+ REQ+ + REQEE+ R+++ REQ+E+ +EQ E+E R+E+++R +++ R+E+
Sbjct: 333 ER-REQQLR-REQEER--REQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQ 388
Query: 409 WRQEKKMREQDEKIREQE---EEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKM- 464
R+E+++R + + REQ+ E+ R+E+++R +++ ++QEE+ E + + + E+++
Sbjct: 389 LRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLK 448
Query: 465 QEQEEK---IQRQEEKIQEQEEK----------TWRQEKLLK-QEEKIWEQEEK----MW 506
+EQEE+ ++R+EE + ++E+ R+E+ LK +EE+ EQ+E+ +
Sbjct: 449 REQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLR 508
Query: 507 RQEEKMWEQEEKMQEQEEKMQR----QEEKMREQEVR----LWQQEEKMQEQEVRLQEL- 557
R++E+ EQ K QE+EE++Q+ +++ REQE R L ++EEK EQE R Q L
Sbjct: 509 REQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLK 568
Query: 558 ---EERLGKLGQKAELLGGAGRESGSQRLP-TLTPILQVELKSQEAQSLQQQQ 606
EER +L ++ E E QRL L+ LK +E + L+Q++
Sbjct: 569 REQEERRDQLLKREE-------ERRQQRLKREQEERLEQRLKREEVERLEQEE 614
Score = 170 bits (430), Expect = 4e-42
Identities = 154/571 (26%), Positives = 296/571 (51%), Gaps = 82/571 (14%)
Query: 40 EQQSKVRNKGHGKPREKSIADEKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQC 99
E++ K + + + REK + Q E E L+ R+ R + +E+D L+E ++ ++
Sbjct: 813 EEEEKEQRRRQRREREKEL------QFLEEEEQLQ-RRERAQQLQEEEDGLQEDQERRRS 865
Query: 100 KESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPW 159
+E + + +E E H ++ +K Q+ + E+ ++ K+
Sbjct: 866 QEQRRDQKWRWQLEE--ERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKR-- 921
Query: 160 LRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDALSLELYRNTITDEELKEK 219
R E Q R E L +E + +R E+ K R YR D++L++K
Sbjct: 922 -RRQEQERQYREEEQLQQEE---EQLLR-----EEREKRRRQERERQYRK---DKKLQQK 969
Query: 220 NAEL----QEKLRLVESEKS-----EIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKE 270
+L EK R E EK E+Q + L R+ + ++ + D L +E
Sbjct: 970 EEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQE 1029
Query: 271 LQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMC--EQELKIREQEEKMW 328
+ + L+ + E+ L Q+ E+ +R+EE++Q++EE++ E+E + R++ E+ +
Sbjct: 1030 EEQL---LREEREKRRL------QERERQYREEEELQQEEEQLLGEERETRRRQELERQY 1080
Query: 329 RQEEKMHEQEEKI-REQEDKMWRQEEK--IREQEEKIREQEEKMWRQEEKIREQDEKIQE 385
R+EE++ ++EE++ RE+ +K RQE + RE+EE +E+E+ + + EK R Q+ + Q
Sbjct: 1081 RKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQY 1140
Query: 386 QEEEMWRQEEK--IREQEEKRQ----EKMWRQEKKMREQDEKIREQEEEMWRQE-EKIRE 438
+EEE +QEE+ +RE+ EKR+ E+ +R+E+++++++E++ +E+E RQE E+
Sbjct: 1141 REEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYR 1200
Query: 439 LEEMMQDQEEKLREVEE------KMQEEEEKM------------QEQEEKIQRQEEKIQE 480
EE +Q Q+ K R +E K Q E EK +E E+ Q ++ ++++
Sbjct: 1201 EEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRD 1260
Query: 481 QEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEK------MQRQEEKM- 533
++ + Q L +Q+E+ EQE + W+Q ++ + +EE+++ +E+K + QEEK
Sbjct: 1261 RQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQL 1320
Query: 534 ----REQEVRLWQQEEKMQEQEVRLQELEER 560
RE++ R + + K +E+E LQE EE+
Sbjct: 1321 LREEREEKRRRQETDRKFREEEQLLQEREEQ 1351
Score = 168 bits (425), Expect = 2e-41
Identities = 166/682 (24%), Positives = 328/682 (48%), Gaps = 135/682 (19%)
Query: 48 KGHGKPREKSIADEKFFQLSEMEAYLENRKRRGTKRWDED----DDLEESEDS----KQC 99
K + REK +E+ Q E + E R++R + W+ D+L++ E+ ++
Sbjct: 980 KRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREERE 1039
Query: 100 KESLKRVTFTLPDDEAIEDA-----GVSHVKKNSDEVKSSFKKRQEKMNEKNYTFRKRVV 154
K L+ ++E ++ G + E++ ++K +E E+ R+
Sbjct: 1040 KRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPE 1099
Query: 155 IKKPWLRLGEVTAQKRPENSLLEET---LHFDHAVRMGTYIEKLTKERDALSLELYRNTI 211
+ R E Q R E L +E L + R +E+ +E + + E +
Sbjct: 1100 KR----RRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQE-EEQLL 1154
Query: 212 TDEELKEKNAELQEKLRLVES--EKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRL-- 267
+E K + EL+ + R E ++ E L + KR+ ER + +++LQ + +
Sbjct: 1155 REEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRY 1214
Query: 268 -----------------------------GKE----LQSVSAKLQAQVEENELWNLLNQQ 294
G+E Q ++L+ + + +L +LL +Q
Sbjct: 1215 RDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQ 1274
Query: 295 QEE------KMWRQ-------EEKIQEQEEKMC---------EQELKIREQEEKMWRQE- 331
QE + W+Q EE+++ +E+K E++L E+EEK RQE
Sbjct: 1275 QERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQET 1334
Query: 332 -EKMHEQEEKIREQEDKMWRQEE---KIREQEEKIREQEEKMWRQEEKIREQDEKIQEQE 387
K E+E+ ++E+E++ R++E K RE+E + +EQ K +E+++R QE+E
Sbjct: 1335 DRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRR-----QERE 1389
Query: 388 EEMWRQEEKIREQEEKRQ-----EKMWRQEKKM---REQDEKIREQEEEMWRQEEKIREL 439
+ ++E+++R QE ++Q ++ +R+E++ +E+D K RE+E+++ RQE + + L
Sbjct: 1390 RKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFL 1449
Query: 440 EE---MMQDQEEKLREVEEKMQEEEEKM---QEQEEKIQRQEEKIQEQE-EKTWRQEKLL 492
EE + Q++ K RE E+ +QE EE+ QE++ K +E++++ QE ++ +R+++L
Sbjct: 1450 EEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELR 1509
Query: 493 KQ--EEKIWEQEEKMWRQ--EEKMWEQEEKMQEQEEKMQRQEE---KMREQEVRLWQQEE 545
Q E K E+E+++ RQ + K ++E++++ QE QR+++ K RE+E ++EE
Sbjct: 1510 SQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREE 1569
Query: 546 ------------KMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVE 593
+++EQ+VR QE E + + Q+ R+ G Q+L + +
Sbjct: 1570 QQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLR------RQEGQQQLRQ-----ERD 1618
Query: 594 LKSQEAQSLQQQQDHYRGHLQQ 615
K +E + L Q+++ + H Q+
Sbjct: 1619 RKFREDEQLLQEREEQQLHRQE 1640
Score = 166 bits (420), Expect = 6e-41
Identities = 156/648 (24%), Positives = 315/648 (48%), Gaps = 83/648 (12%)
Query: 35 HINKLEQQSKV-RNKGHGKPREKSIADEKFFQLSEMEAYLENRKR----RGTKRWDEDDD 89
H K EQ+ + R K + R + E+ + E E + KR +RW + ++
Sbjct: 434 HEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEE 493
Query: 90 LEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSFKKRQEKMNEKNYTF 149
E E ++ ++ L+R E+ +K+ +E + + R E+ +
Sbjct: 494 EERREQQERREQQLRREQ---------EERREQRLKRQEEEERLQQRLRSEQQLRREQEE 544
Query: 150 RKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDALSLELYRN 209
R+ ++K+ +KR E E+ L + R + L +E + L R
Sbjct: 545 RREQLLKRE--------EEKRLEQERREQRLKREQEERRD---QLLKREEERRQQRLKRE 593
Query: 210 TITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGK 269
EE E+ + +E RL + E+ E +L ++ + + R QLL ++Q + +L +
Sbjct: 594 ---QEERLEQRLKREEVERLEQEERREQRLKREEPEEE-RRQQLLKSEEQEERRQQQLRR 649
Query: 270 ELQSV-SAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMW 328
E Q +L+ + EE L L ++ EE+ R+E+++ E+E++ + +K R + + W
Sbjct: 650 EQQERREQRLKREEEEERLEQRLKREHEEE--RREQELAEEEQEQARERIKSRIPKWQ-W 706
Query: 329 RQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEE 388
+ E + ++ K+ + K Q + ++E++ R + E W++EE+ Q ++ +++ +
Sbjct: 707 QLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRD 766
Query: 389 EMWRQEEKIREQ------------EEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKI 436
W+ + + + + E+R+ ++ +E++ REQ E+E+E R++ +
Sbjct: 767 FTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRRE 826
Query: 437 RELEEMMQDQEEKL--REVEEKMQEEEEKMQEQEEKIQRQEEKIQ-------EQEEKTWR 487
RE E ++EE+L RE +++QEEE+ +QE +E+ + QE++ E+E K R
Sbjct: 827 REKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRR 886
Query: 488 ---------QEKLLKQEEKIWEQEEKMWRQE-EKMWEQEEKMQEQEEKMQRQEEKM---R 534
QE+L K+++ + E+EE++ R+E EK QE++ Q +EE+ +QEE+
Sbjct: 887 HTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLRE 946
Query: 535 EQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVEL 594
E+E R Q+ E+ ++ +LQ+ EE+L LG++ E RE + + EL
Sbjct: 947 EREKRRRQERERQYRKDKKLQQKEEQL--LGEEPEKRRRQEREKKYRE--------EEEL 996
Query: 595 KSQEAQSLQQQQDHYRGHLQQYVAAYQQLASGKEALPSCSSRKLRAKR 642
+ +E Q L+++++ R Q++ Y++ K+ L + LR +R
Sbjct: 997 QQEEEQLLREEREKRR--RQEWERQYRK----KDELQQEEEQLLREER 1038
Score = 164 bits (414), Expect = 3e-40
Identities = 163/671 (24%), Positives = 319/671 (47%), Gaps = 104/671 (15%)
Query: 18 DPTKSPVLSDEDSDLDFHINKLEQQSKVRNKGHGKPREKSIADEKFFQLSEMEAYLENRK 77
+P + L +E+ L KLE+Q R + + +++ + E+ + + E E ++
Sbjct: 264 EPQRQRELQEEEEQL----RKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQE 319
Query: 78 RRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSFKK 137
R ++ + E E + ++ +R + E E+ +++ +E + +
Sbjct: 320 ERREQQERREQQEERREQQLRREQEERREQQLRREQE--EERREQQLRREQEEERREQQL 377
Query: 138 RQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTK 197
R+E+ + R+ +++ +L +R + E+ L + +R + +
Sbjct: 378 RREQQLRREQQLRREQQLRREQ-QLRREQQLRREQQLRREQQLRREQQLR-----REQEE 431
Query: 198 ERDALSLELYRNTITDEELKEKNAELQEKL-RLVESEKSEIQLNVKDLKRKLERAQLLLP 256
ER E R ++ LK + E ++ L R E+E+ E + + LKR E +
Sbjct: 432 ERHEQKHEQERR---EQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERR--- 485
Query: 257 QQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMW---RQEEKIQEQEEKM 313
++ L++E + ++ + +L+ + EE L Q++EE++ R E++++ ++E+
Sbjct: 486 ERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEER 545
Query: 314 CEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWR-- 371
EQ LK +EEK QE + + + E+ D++ ++EE+ R+Q K REQEE++ +
Sbjct: 546 REQLLK--REEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLK-REQEERLEQRL 602
Query: 372 --------QEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIR 423
++E+ REQ K +E EEE +Q K EQEE+RQ+++ R++++ REQ K
Sbjct: 603 KREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKRE 662
Query: 424 EQEEEMW----RQEEKIRELEEMMQDQEEKLRE-------------------------VE 454
E+EE + R+ E+ R +E+ ++++E+ RE
Sbjct: 663 EEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSR 722
Query: 455 EKMQEEEEKMQEQEEKIQRQEEKIQEQEEK---------------TWRQEKLLKQEE--- 496
+ QE + + QEQEEK +R+E ++Q QEE+ TW+ + K E
Sbjct: 723 PRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQ 782
Query: 497 ------KIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKM-REQEVRLWQQEEKMQE 549
+ EQ E+ R EE+ ++ + E+EEK QR+ ++ RE+E++ ++EE++Q
Sbjct: 783 RLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQR 842
Query: 550 QEVRLQELEERLGKLGQKAELLGGAGR-----------ESGSQRLPTL--TPILQVELKS 596
+E R Q+L+E L + E + E +R TL P LQ +L+
Sbjct: 843 RE-RAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLR- 900
Query: 597 QEAQSLQQQQD 607
+E Q LQ++++
Sbjct: 901 KEQQLLQEEEE 911
Score = 162 bits (410), Expect = 9e-40
Identities = 163/719 (22%), Positives = 330/719 (45%), Gaps = 125/719 (17%)
Query: 4 DNPEVSERANSSKFDPTKSPVLSDEDS--DLDFHINKLEQQSKVRNKGHGKPREKSIADE 61
DN + + +F + L D S DL + + +++ + + + + R++ +E
Sbjct: 1237 DNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEE 1296
Query: 62 KFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGV 121
+ + E + KRR K +E L E + K+ ++ R +++ +++
Sbjct: 1297 EQLEREEQK----EAKRRDRKSQEEKQLLREEREEKRRRQETDRKF--REEEQLLQEREE 1350
Query: 122 SHVKKNSDEVKSSFKKRQEKMNEKNYTF-----------RKRVVIKKPW-LRLGEVTAQK 169
+++ + K F++ + + E+ F R+R +K+ LR E Q
Sbjct: 1351 QPLRRQERDRK--FREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQL 1408
Query: 170 RPEN-----------SLLEETLHF---DHAVRMGTYIEKLTKERDALSLELYRNTITDEE 215
R + S E F + VR K +E L E +R +E+
Sbjct: 1409 RQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQ 1468
Query: 216 L----KEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKEL 271
L +E+ QE+ R E+ +++ +D K + + + P+++ E +L ++
Sbjct: 1469 LLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQ 1528
Query: 272 QSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQE 331
+ + Q + +Q ++ +R+EE+++++ E EQ+L +E++ K +E
Sbjct: 1529 RQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQERE---EQQLSRQERDRKFRLEE 1585
Query: 332 EKMH--EQEEKIREQEDKMWRQE----------EKIREQEEKIREQEEKMWRQEE----- 374
+K+ EQE K E E ++ RQE K RE E+ ++E+EE+ ++E
Sbjct: 1586 QKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKF 1645
Query: 375 ----------------------KIREQDEKIQEQEEEMWRQEEKIRE-QEEKRQEKMWRQ 411
K RE+++ +QE EE+ R++E+ R+ +EE++Q + +
Sbjct: 1646 LEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQER 1705
Query: 412 EKKMREQDEKIREQE-EEMWRQEEKIR-ELEEMMQDQEEKLREVEEKMQ------EEEEK 463
E+K ++++++R QE E +R+EE++R E E+ ++E+ R++ E+ Q E++ +
Sbjct: 1706 ERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLR 1765
Query: 464 MQEQEEKIQRQEEKIQEQEEKTWRQE----KLLKQEEKIWEQEEKMWRQEEK----MWEQ 515
QE++ K + +E+ QE+EE+ R + K ++E+ E+EE+ R +++ WE+
Sbjct: 1766 RQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEE 1825
Query: 516 EEKMQEQEEKMQRQE--------------EKMREQEVRLWQQEE---------KMQEQEV 552
E+ E++E+ RQE EK R +E LWQ+EE K++E+ +
Sbjct: 1826 EQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHI 1885
Query: 553 RLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEA-QSLQQQQDHYR 610
R Q+ EE+ + Q E+ G+ G P V ++S + +Q+Q+ YR
Sbjct: 1886 RRQQKEEQRHR--QVGEIKSQEGKGHGRLLEPGTHQFASVPVRSSPLYEYIQEQRSQYR 1942
Score = 151 bits (381), Expect = 2e-36
Identities = 128/459 (27%), Positives = 259/459 (56%), Gaps = 59/459 (12%)
Query: 217 KEKNAELQEKLRLVESEKSEI-QLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVS 275
+EK A K L++ + E Q + R+LE +Q+ Q E +R E + S
Sbjct: 97 EEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQ-EQERELAEGEEQS 155
Query: 276 AKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQEL--KIREQEEKMWRQEEK 333
K Q ++E+ + Q+++E++WRQ ++ QE+EE+ E+E + E + + EE+
Sbjct: 156 EK-QERLEQRD-----RQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQ 209
Query: 334 MHEQE-----EKIRE--QEDKMWRQEEKIREQEEK-IREQEEKMWRQEEKIREQD----E 381
+ +E K RE Q+ + RQ+ +E+EEK R++E + ++EEK++E++
Sbjct: 210 LRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQR 269
Query: 382 KIQEQEEEMWRQE----EKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIR 437
++QE+EE++ + E + R++EE++Q+++ R+++ R+Q+E+ REQ+EE Q+E+
Sbjct: 270 ELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERRE 329
Query: 438 ELEE-----------------MMQDQEEKLREVEEKMQEEEEKMQEQ---EEKIQRQEEK 477
+ EE + ++QEE+ RE + + ++EEE+ ++Q E++++R+++
Sbjct: 330 QQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQL 389
Query: 478 IQEQE---EKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKM- 533
+EQ+ E+ R+E+ L++E+++ +E+++ R+++ EQEE+ EQ+ + +R+E+++
Sbjct: 390 RREQQLRREQQLRREQQLRREQQL-RREQQLRREQQLRREQEEERHEQKHEQERREQRLK 448
Query: 534 REQEVRL-W---QQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPI 589
REQE R W ++E + EQE R Q+L+ + ++ E E ++
Sbjct: 449 REQEERRDWLKREEETERHEQERRKQQLKR--DQEEERRERWLKLEEEERREQQERREQQ 506
Query: 590 LQVELKSQEAQSLQQQQDHYRGHLQQYVAAYQQLASGKE 628
L+ E + + Q L++Q++ R LQQ + + QQL +E
Sbjct: 507 LRREQEERREQRLKRQEEEER--LQQRLRSEQQLRREQE 543
Score = 143 bits (361), Expect = 4e-34
Identities = 105/355 (29%), Positives = 206/355 (58%), Gaps = 36/355 (10%)
Query: 291 LNQQQEEKMWRQEEKIQEQEEKMCEQELKIRE---QEEKMWRQEEKMHEQEEKIREQEDK 347
L++++ + +E +Q++ ++ ++ + R+ +EE R+ +K EQE ++ E E++
Sbjct: 95 LDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQ 154
Query: 348 MWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEE---------EMWRQEEKIR 398
+QE EQ ++ R EE +WRQ ++ +E++E+ E+E+ E + EE++R
Sbjct: 155 SEKQERL--EQRDRQRRDEE-LWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLR 211
Query: 399 EQ---EEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEE 455
+ E +R+ + +Q+++ QD +E+EE+ WR+ E + EE +EE R+ E
Sbjct: 212 RRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRE- 270
Query: 456 KMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLL--KQEEKIWEQEEKMWRQEEKMW 513
+QEEEE++++ E + R+E + +EQ+++ R+E+ L KQEE+ EQ+E+ Q+E+
Sbjct: 271 -LQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERRE 329
Query: 514 EQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGG 573
+QEE+ +E++++R++E+ REQ++R Q+EE+ ++Q R QE E R +L ++ +L
Sbjct: 330 QQEER---REQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQL--- 383
Query: 574 AGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQQYVAAYQQLASGKE 628
RE +R L+ E + + Q L+++Q R +Q + QQL +E
Sbjct: 384 -RREQQLRR----EQQLRREQQLRREQQLRREQQLRR---EQQLRREQQLRREQE 430
>gi|31317305 M-phase phosphoprotein 10 [Homo sapiens]
Length = 681
Score = 177 bits (449), Expect = 3e-44
Identities = 144/469 (30%), Positives = 234/469 (49%), Gaps = 54/469 (11%)
Query: 2 GGDNPEVSERANSSKFDPTKSPVLSDEDSDLDFHINKLEQQSKVRNKGHGKPREKSIADE 61
G + + + + K+ PV SDED + H ++L+ + + IA+E
Sbjct: 251 GSKKLKSGKSSRNLKYKDFFDPVESDEDIT-NVHDDELDSNKE----------DDEIAEE 299
Query: 62 KFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGV 121
+ +LS E DEDDDL+E+ED+KQ KESLKRVTF LPDD ED GV
Sbjct: 300 EAEELSISET-------------DEDDDLQENEDNKQHKESLKRVTFALPDDAETEDTGV 346
Query: 122 SHVKKNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLH 181
+VKKNSDEVKSSF+KRQEKMNEK + K ++ KKPW GEVTAQKRPENSLLEETLH
Sbjct: 347 LNVKKNSDEVKSSFEKRQEKMNEKIASLEKELLEKKPWQLQGEVTAQKRPENSLLEETLH 406
Query: 182 FDHAVRMGTYI--------EKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESE 233
FDHAVRM I E + K+R + + + + + E+ KE E +++L L + E
Sbjct: 407 FDHAVRMAPVITEETTLQLEDIIKQR--IRDQAWDDVVRKEKPKEDAYEYKKRLTL-DHE 463
Query: 234 KSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQ 293
KS++ L E+ + L QQ+ E + E+Q + L +++ ++ +
Sbjct: 464 KSKL-----SLAEIYEQEYIKLNQQKTAEEENPEHVEIQKMMDSLFLKLDALSNFHFI-- 516
Query: 294 QQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEE 353
K E K+ I +E + E+I+E+ +
Sbjct: 517 ----------PKPPVPEIKVVSNLPAITMEEVAPVSVSDAALLAPEEIKEKNKAGDIKTA 566
Query: 354 KIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEK 413
+ +K RE+ +K +++ KI+E++++ + E+ Q K + EK+ + K
Sbjct: 567 AEKTATDKKRERRKKKYQKRMKIKEKEKRRKLLEKSSVDQAGKY--SKTVASEKLKQLTK 624
Query: 414 KMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462
+ K +++ + + +L++ ++ Q ++ E+K ++ ++
Sbjct: 625 TGKASFIKDEGKDKALKSSQAFFSKLQDQVKMQINDAKKTEKKKKKRQD 673
Score = 50.1 bits (118), Expect = 7e-06
Identities = 79/421 (18%), Positives = 185/421 (43%), Gaps = 67/421 (15%)
Query: 210 TITDEELKE-KNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLG 268
TI DE++ +E QE+ E + SEI+ + K+ LE ++ + + +G
Sbjct: 98 TINDEDISLLPESEEQER----EEDGSEIEADDKEDLEDLEEEEV----SDMGNDDPEMG 149
Query: 269 K--ELQSVSAKLQAQV---EENEL-WNLLNQQQEEKMW-------RQEEKIQEQEEKMCE 315
+ E S S ++ V E+++L +++ +Q+ K+ R++ + ++ K+ E
Sbjct: 150 ERAENSSKSDLRKSPVFSDEDSDLDFDISKLEQQSKVQNKGQGKPREKSIVDDKFFKLSE 209
Query: 316 QELKIREQEEKMWRQEEKMHEQE-----EKIREQED----------KMWRQEEKIREQE- 359
E + E++ R+++ E+E E I ED K + ++ ++
Sbjct: 210 MEAYLENIEKEEERKDDNDEEEEDIDFFEDIDSDEDEGGLFGSKKLKSGKSSRNLKYKDF 269
Query: 360 -EKIREQEEKMWRQEEKI---REQDEKIQEQEEEM----WRQEEKIREQEEKRQEKMWRQ 411
+ + E+ ++++ +E DE +E+ EE+ +++ ++E E+ +Q K +
Sbjct: 270 FDPVESDEDITNVHDDELDSNKEDDEIAEEEAEELSISETDEDDDLQENEDNKQHKESLK 329
Query: 412 EKKMREQDEKIREQEEEM---WRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE-KMQEQ 467
D+ E + +E E+ + EK+ +E+++ E++ ++Q +
Sbjct: 330 RVTFALPDDAETEDTGVLNVKKNSDEVKSSFEKRQEKMNEKIASLEKELLEKKPWQLQGE 389
Query: 468 EEKIQRQEEKIQEQ---------------EEKTWRQEKLLKQE--EKIWEQEEKMWRQEE 510
+R E + E+ EE T + E ++KQ ++ W+ + + +E
Sbjct: 390 VTAQKRPENSLLEETLHFDHAVRMAPVITEETTLQLEDIIKQRIRDQAWDDVVRKEKPKE 449
Query: 511 KMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAEL 570
+E ++++ EK + ++ EQE Q++ +E+ E+++ + L K +
Sbjct: 450 DAYEYKKRLTLDHEKSKLSLAEIYEQEYIKLNQQKTAEEENPEHVEIQKMMDSLFLKLDA 509
Query: 571 L 571
L
Sbjct: 510 L 510
Score = 47.4 bits (111), Expect = 4e-05
Identities = 55/257 (21%), Positives = 115/257 (44%), Gaps = 25/257 (9%)
Query: 324 EEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIR---EQEEKIREQEEKMWRQEEKIREQD 380
+E++W+Q E +E + + +E I E EE+ RE++ ++K E
Sbjct: 73 DEQIWQQLELQNEPILQYFQNAVSETINDEDISLLPESEEQEREEDGSEIEADDK--EDL 130
Query: 381 EKIQEQE-EEMWRQEEKIREQEEKRQEKMWRQEKKMREQDE-------KIREQEEEMWRQ 432
E ++E+E +M + ++ E+ E + R+ ++D K+ +Q + +
Sbjct: 131 EDLEEEEVSDMGNDDPEMGERAENSSKSDLRKSPVFSDEDSDLDFDISKLEQQSKVQNKG 190
Query: 433 EEKIRELEEMMQDQEEKLREVE------EKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTW 486
+ K RE + ++ D+ KL E+E EK +E ++ E+EE I E+ +++E
Sbjct: 191 QGKPRE-KSIVDDKFFKLSEMEAYLENIEKEEERKDDNDEEEEDIDFFEDIDSDEDEGGL 249
Query: 487 RQEKLLKQEE-----KIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLW 541
K LK + K + + + E+ ++++ +E + EE+ E +
Sbjct: 250 FGSKKLKSGKSSRNLKYKDFFDPVESDEDITNVHDDELDSNKEDDEIAEEEAEELSISET 309
Query: 542 QQEEKMQEQEVRLQELE 558
+++ +QE E Q E
Sbjct: 310 DEDDDLQENEDNKQHKE 326
>gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo
sapiens]
Length = 693
Score = 155 bits (392), Expect = 1e-37
Identities = 109/424 (25%), Positives = 228/424 (53%), Gaps = 38/424 (8%)
Query: 164 EVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDALSLELYRNTITDEELK--EKNA 221
E Q+R + ++ E L H ++ ++++ ERD Y I E + E+
Sbjct: 194 EAVLQRRLQQTIKERALLNAHVTQVTESLKQVQLERDE-----YAKHIKGERARWQERMW 248
Query: 222 ELQEKLRLVESEKS-------EIQLNVKDLKRKLERAQLLLPQ------QQLQVEADRLG 268
++ + R ++ EK E++ ++ +LK ++ L P +QLQ EA L
Sbjct: 249 KMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLR 308
Query: 269 KELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMW 328
+E++ + KLQ+QVE N+ +LL+++Q++++ QEE ++EQE + ++ ++ EQ E++
Sbjct: 309 QEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLR 368
Query: 329 RQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEE 388
Q++ + EQ E++R+QE ++ +QEE++R++EE++++QE+++W QEE++ +++E++Q+QEE
Sbjct: 369 EQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEE 428
Query: 389 EM-WRQEEKIREQEEKRQ---EKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQ 444
+ Q K+ +Q + Q E + ++K + +++++E +E++ EE + + Q
Sbjct: 429 RLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKL--DEEHLEAASQRNQ 486
Query: 445 DQEEKLREVEEKMQ-EEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEE 503
E +L V + + + + +EE+ R I E E + ++ + E
Sbjct: 487 QLETQLSLVALPGEGDGGQHLDSEEEEAPRPTPNIPEDLESREATSSFMDLPKEKADGTE 546
Query: 504 KMWRQE----------EKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVR 553
++ R+E + M E + Q + ++M E +RL Q+EE+M+ + +
Sbjct: 547 QVERRELGFVQPSGVTDGMRESFTVYESQGAVPNTRHQEM-EDVIRLAQKEEEMKVKLLE 605
Query: 554 LQEL 557
LQEL
Sbjct: 606 LQEL 609
Score = 145 bits (367), Expect = 9e-35
Identities = 125/528 (23%), Positives = 251/528 (47%), Gaps = 73/528 (13%)
Query: 136 KKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKL 195
+ RQ K+ ++ K P + G T +K+ ++S T H+ Y E
Sbjct: 16 ESRQNKLAAAKKKLKEYQQRKSPGIPAGAKTKKKKTDSSPETTTSGGGHSPGDSQYQE-- 73
Query: 196 TKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRK-------- 247
L++ L +++T +L E L+++ + VE + E + ++ +
Sbjct: 74 ------LAVALESSSVTINQLNENIESLKQQKKQVEHQLEEAKKTNNEIHKAQMEQLETI 127
Query: 248 ----LERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVE-----ENELWNLLNQQQEEK 298
LE+A L + A +E + ++ +LQ ++ E L + QQQEE
Sbjct: 128 NILTLEKADLKTTLYHTKRAARHFEEESKDLAGRLQYSLQHIQELERALCAVSTQQQEED 187
Query: 299 MWRQEEKIQEQEEKMCEQELKIRE-------------QEEKMWRQEEKMHEQEEKIREQE 345
R + ++ +Q +K R ++ ++ R E H + E+ R QE
Sbjct: 188 --RSSSCREAVLQRRLQQTIKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERARWQE 245
Query: 346 DKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQE-----------EEMWRQE 394
+MW+ + R +E+ + ++ E + E ++ E E++ +
Sbjct: 246 -RMWKMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEA 304
Query: 395 EKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVE 454
+ +R++ E + K+ Q + + +EQ++ + QEE +RE E ++E+L E
Sbjct: 305 KHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQN 364
Query: 455 EKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQE-KLLKQEEKIWEQEEKMWRQEEKMW 513
E+++E+++ +QEQ E++++QE+++++QEE+ ++E +L KQE+++W+QEE++W++EE++
Sbjct: 365 ERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQ 424
Query: 514 EQEEKMQ-EQEEKMQRQ-------------EEKMR---EQEVRLWQQ---EEKMQEQEVR 553
+QEE++ Q K+ +Q E+K EQ+V+ Q+ EE ++ R
Sbjct: 425 KQEERLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASQR 484
Query: 554 LQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQS 601
Q+LE +L + E GG +S + P TP + +L+S+EA S
Sbjct: 485 NQQLETQLSLVALPGEGDGGQHLDSEEEEAPRPTPNIPEDLESREATS 532
>gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C
isoform 1 [Homo sapiens]
Length = 693
Score = 155 bits (392), Expect = 1e-37
Identities = 109/424 (25%), Positives = 228/424 (53%), Gaps = 38/424 (8%)
Query: 164 EVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDALSLELYRNTITDEELK--EKNA 221
E Q+R + ++ E L H ++ ++++ ERD Y I E + E+
Sbjct: 194 EAVLQRRLQQTIKERALLNAHVTQVTESLKQVQLERDE-----YAKHIKGERARWQERMW 248
Query: 222 ELQEKLRLVESEKS-------EIQLNVKDLKRKLERAQLLLPQ------QQLQVEADRLG 268
++ + R ++ EK E++ ++ +LK ++ L P +QLQ EA L
Sbjct: 249 KMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLR 308
Query: 269 KELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMW 328
+E++ + KLQ+QVE N+ +LL+++Q++++ QEE ++EQE + ++ ++ EQ E++
Sbjct: 309 QEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLR 368
Query: 329 RQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEE 388
Q++ + EQ E++R+QE ++ +QEE++R++EE++++QE+++W QEE++ +++E++Q+QEE
Sbjct: 369 EQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEE 428
Query: 389 EM-WRQEEKIREQEEKRQ---EKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQ 444
+ Q K+ +Q + Q E + ++K + +++++E +E++ EE + + Q
Sbjct: 429 RLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKL--DEEHLEAASQRNQ 486
Query: 445 DQEEKLREVEEKMQ-EEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEE 503
E +L V + + + + +EE+ R I E E + ++ + E
Sbjct: 487 QLETQLSLVALPGEGDGGQHLDSEEEEAPRPTPNIPEDLESREATSSFMDLPKEKADGTE 546
Query: 504 KMWRQE----------EKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVR 553
++ R+E + M E + Q + ++M E +RL Q+EE+M+ + +
Sbjct: 547 QVERRELGFVQPSGVTDGMRESFTVYESQGAVPNTRHQEM-EDVIRLAQKEEEMKVKLLE 605
Query: 554 LQEL 557
LQEL
Sbjct: 606 LQEL 609
Score = 145 bits (366), Expect = 1e-34
Identities = 125/528 (23%), Positives = 251/528 (47%), Gaps = 73/528 (13%)
Query: 136 KKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKL 195
+ RQ K+ ++ K P + G T +K+ ++S T H+ Y E
Sbjct: 16 ESRQNKLAAAKKKLKEYQQRKSPGIPAGAKTKKKKTDSSPETTTSGGGHSPGDSQYQE-- 73
Query: 196 TKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRK-------- 247
L++ L +++T +L E L+++ + VE + E + ++ +
Sbjct: 74 ------LAVALESSSVTINQLNENIESLKQQKKQVEHQLEEAKKTNNEIHKAQMEQLETI 127
Query: 248 ----LERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVE-----ENELWNLLNQQQEEK 298
LE+A L + A +E + ++ +LQ ++ E L + QQQEE
Sbjct: 128 NILTLEKADLKTTLYHTKRAARHFEEESKDLAGRLQYSLQRIQELERALSAVSTQQQEED 187
Query: 299 MWRQEEKIQEQEEKMCEQELKIRE-------------QEEKMWRQEEKMHEQEEKIREQE 345
R + ++ +Q +K R ++ ++ R E H + E+ R QE
Sbjct: 188 --RSSSCREAVLQRRLQQTIKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERARWQE 245
Query: 346 DKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQE-----------EEMWRQE 394
+MW+ + R +E+ + ++ E + E ++ E E++ +
Sbjct: 246 -RMWKMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEA 304
Query: 395 EKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVE 454
+ +R++ E + K+ Q + + +EQ++ + QEE +RE E ++E+L E
Sbjct: 305 KHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQN 364
Query: 455 EKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQE-KLLKQEEKIWEQEEKMWRQEEKMW 513
E+++E+++ +QEQ E++++QE+++++QEE+ ++E +L KQE+++W+QEE++W++EE++
Sbjct: 365 ERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQ 424
Query: 514 EQEEKMQ-EQEEKMQRQ-------------EEKMR---EQEVRLWQQ---EEKMQEQEVR 553
+QEE++ Q K+ +Q E+K EQ+V+ Q+ EE ++ R
Sbjct: 425 KQEERLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASQR 484
Query: 554 LQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQS 601
Q+LE +L + E GG +S + P TP + +L+S+EA S
Sbjct: 485 NQQLETQLSLVALPGEGDGGQHLDSEEEEAPRPTPNIPEDLESREATS 532
>gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo
sapiens]
Length = 693
Score = 154 bits (389), Expect = 2e-37
Identities = 108/424 (25%), Positives = 228/424 (53%), Gaps = 38/424 (8%)
Query: 164 EVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDALSLELYRNTITDEELK--EKNA 221
E +R + ++ E L H ++ ++++ ERD Y I E + E+
Sbjct: 194 EAVLHRRLQQTIKERALLNAHVTQVTESLKQVQLERDE-----YAKHIKGERARWQERMW 248
Query: 222 ELQEKLRLVESEKS-------EIQLNVKDLKRKLERAQLLLPQ------QQLQVEADRLG 268
++ + R ++ EK E++ ++ +LK ++ + L P +QLQ EA L
Sbjct: 249 KMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAKPPSLAPPAVTSVVEQLQDEAKHLR 308
Query: 269 KELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMW 328
+E++ + KLQ+QVE N+ +LL+++Q++++ QEE ++EQE + ++ ++ EQ E++
Sbjct: 309 QEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEVQRVREQERLCEQNERLR 368
Query: 329 RQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEE 388
Q++ + EQ E++R+QE ++ +QEE++R++EE++++QE+++W QEE++ +++E++Q+QEE
Sbjct: 369 EQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEE 428
Query: 389 EM-WRQEEKIREQEEKRQ---EKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQ 444
+ Q K+ +Q + Q E + ++K + +++++E +E++ EE + + Q
Sbjct: 429 RLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKL--DEEHLEAASQQNQ 486
Query: 445 DQEEKLREVEEKMQ-EEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEE 503
E +L V + + + + +EE+ R I E E + ++ + E
Sbjct: 487 QLETQLSLVALPGEGDGGQHLDSEEEEAPRPTPNIPEDLESREATSSFMDLPKEKADGTE 546
Query: 504 KMWRQE----------EKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVR 553
++ R+E + M E + Q + ++M E +RL Q+EE+M+ + +
Sbjct: 547 QVERRELGFVQPSGVTDGMRESFTVYESQGAVPNTRHQEM-EDVIRLAQKEEEMKVKLLE 605
Query: 554 LQEL 557
LQEL
Sbjct: 606 LQEL 609
Score = 143 bits (360), Expect = 6e-34
Identities = 126/523 (24%), Positives = 260/523 (49%), Gaps = 63/523 (12%)
Query: 136 KKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKL 195
+ RQ K+ ++ K P + G T +K+ ++S T H+ Y ++L
Sbjct: 16 ESRQNKLAAAKKKLKEYQQRKSPGIPAGAKTKKKKTDSSPETTTSGGGHSPGDSQY-QEL 74
Query: 196 TKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKR-------KL 248
++ S+ + + E LK++ +++ +L E++K+ +++ ++R L
Sbjct: 75 AVALESSSVTISQLNENIESLKQQKKQVEHQLE--EAKKTNNEIHKAQMERLETINILTL 132
Query: 249 ERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVE-----ENELWNLLNQQQEEKMWRQE 303
E+A L + A +E + ++ +LQ ++ E L + QQQEE R
Sbjct: 133 EKADLKTTLYHTKRAARHFEEESKDLAGRLQYSLQRIQELERALCAVSTQQQEED--RSS 190
Query: 304 EKIQEQEEKMCEQELKIRE-------------QEEKMWRQEEKMHEQEEKIREQEDKMWR 350
+ + +Q +K R ++ ++ R E H + E+ R QE +MW+
Sbjct: 191 SCREAVLHRRLQQTIKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERARWQE-RMWK 249
Query: 351 QEEKIRE-QEEKIRE--QEEKMWRQEEKIREQDEK--------IQEQEEEMWRQEEKIRE 399
+ R +EEK R+ + +++ R +++ Q K + E++ + + +R+
Sbjct: 250 MSVEARTLKEEKKRDIHRIQELERSLSELKNQMAKPPSLAPPAVTSVVEQLQDEAKHLRQ 309
Query: 400 QEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQE 459
+ E + K+ Q + + +EQ++ + QEE +RE E ++E+L E E+++E
Sbjct: 310 EVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEVQRVREQERLCEQNERLRE 369
Query: 460 EEEKMQEQEEKIQRQEEKIQEQEEKTWRQE-KLLKQEEKIWEQEEKMWRQEEKMWEQEEK 518
+++ +QEQ E++++QE+++++QEE+ ++E +L KQE+++W+QEE++W++EE++ +QEE+
Sbjct: 370 QQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEER 429
Query: 519 MQ-EQEEKMQRQ-------------EEKMR---EQEVRLWQQ---EEKMQEQEVRLQELE 558
+ Q K+ +Q E+K EQ+V+ Q+ EE ++ + Q+LE
Sbjct: 430 LALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASQQNQQLE 489
Query: 559 ERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQS 601
+L + E GG +S + P TP + +L+S+EA S
Sbjct: 490 TQLSLVALPGEGDGGQHLDSEEEEAPRPTPNIPEDLESREATS 532
>gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo
sapiens]
Length = 693
Score = 152 bits (383), Expect = 1e-36
Identities = 108/424 (25%), Positives = 226/424 (53%), Gaps = 38/424 (8%)
Query: 164 EVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDALSLELYRNTITDEELK--EKNA 221
E Q+ + ++ E L H ++ ++++ ERD Y I E + E+
Sbjct: 194 EAVLQRWLQQTIKERALLNAHVTQVTESLKQVQLERDE-----YAKHIKGERARWQERMW 248
Query: 222 ELQEKLRLVESEKS-------EIQLNVKDLKRKLERAQLLLPQ------QQLQVEADRLG 268
++ + R ++ EK E++ ++ +LK ++ L P +QLQ EA L
Sbjct: 249 KMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLR 308
Query: 269 KELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMW 328
+E++ + KLQ+QVE N+ +LL+++Q++++ QEE ++EQE + ++ ++ EQ E++
Sbjct: 309 QEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLR 368
Query: 329 RQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEE 388
Q++ + EQ E++R+QE ++ +QEE++R++EE++++QE+++W QEE++ +++E++Q+QEE
Sbjct: 369 EQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEE 428
Query: 389 EM-WRQEEKIREQEEKRQ---EKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQ 444
+ Q K+ +Q + Q E + ++K + +++++E +E++ EE + Q
Sbjct: 429 RLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKL--DEEHLEAASHQNQ 486
Query: 445 DQEEKLREVEEKMQ-EEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEE 503
E +L V + + + + +EE+ R I E E + ++ + E
Sbjct: 487 QLETQLSLVALPGEGDGGQHLDSEEEEAPRPTPNIPEDLESREATSSFMDLPKEKADGTE 546
Query: 504 KMWRQE----------EKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVR 553
++ R+E + M E + Q + ++M E +RL Q+EE+M+ + +
Sbjct: 547 QVERRELGFVQPSGVTDGMRESFTVYESQGAVPNTRHQEM-EDVIRLAQKEEEMKVKLLE 605
Query: 554 LQEL 557
LQEL
Sbjct: 606 LQEL 609
Score = 144 bits (363), Expect = 3e-34
Identities = 123/523 (23%), Positives = 256/523 (48%), Gaps = 63/523 (12%)
Query: 136 KKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKL 195
+ RQ K+ ++ K P + G T +K+ ++S T H+ Y ++L
Sbjct: 16 ESRQNKLAAAKKKLKEYQQRKSPGIPAGAKTKKKKTDSSPETTTSGGCHSPGDSQY-QEL 74
Query: 196 TKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKR-------KL 248
++ S+ + + E LK++ +++ +L E++K+ +++ ++R L
Sbjct: 75 AVALESSSVTISQLNENIESLKQQKKQVEHQLE--EAKKTNNEIHKAQMERLETINILTL 132
Query: 249 ERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVE-----ENELWNLLNQQQEEKMWRQE 303
E+A L + A +E + ++ +LQ ++ E L + QQQEE R
Sbjct: 133 EKADLKTTLYHTKRAARHFEEESKDLAGRLQYSLQRIQELERALCAVSTQQQEED--RSS 190
Query: 304 EKIQEQEEKMCEQELKIRE-------------QEEKMWRQEEKMHEQEEKIREQEDKMWR 350
+ ++ +Q +K R ++ ++ R E H + E+ R QE +MW+
Sbjct: 191 SCREAVLQRWLQQTIKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERARWQE-RMWK 249
Query: 351 QEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQE-----------EEMWRQEEKIRE 399
+ R +E+ + ++ E + E ++ E E++ + + +R+
Sbjct: 250 MSVEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQ 309
Query: 400 QEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQE 459
+ E + K+ Q + + +EQ++ + QEE +RE E ++E+L E E+++E
Sbjct: 310 EVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLRE 369
Query: 460 EEEKMQEQEEKIQRQEEKIQEQEEKTWRQE-KLLKQEEKIWEQEEKMWRQEEKMWEQEEK 518
+++ +QEQ E++++QE+++++QEE+ ++E +L KQE+++W+QEE++W++EE++ +QEE+
Sbjct: 370 QQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEER 429
Query: 519 MQ-EQEEKMQRQ-------------EEKMR---EQEVRLWQQ---EEKMQEQEVRLQELE 558
+ Q K+ +Q E+K EQ+V+ Q+ EE ++ + Q+LE
Sbjct: 430 LALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASHQNQQLE 489
Query: 559 ERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQS 601
+L + E GG +S + P TP + +L+S+EA S
Sbjct: 490 TQLSLVALPGEGDGGQHLDSEEEEAPRPTPNIPEDLESREATS 532
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 148 bits (374), Expect = 1e-35
Identities = 89/383 (23%), Positives = 214/383 (55%), Gaps = 35/383 (9%)
Query: 214 EELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQS 273
E+L + LQE +L E ++ N+ K K E+ + L+ E R G+E +
Sbjct: 1501 EKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSK-EQQYKDEEEVTLEEEVSREGEEKEQ 1559
Query: 274 VSAKLQAQVEENELWNLLNQQQ---EEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQ 330
+ Q ++E W +++++ E+K ++E K+ ++EEK+ ++E ++ ++E K+ +
Sbjct: 1560 QVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQA 1619
Query: 331 EEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEM 390
K+ + + ++ + E K ++EE + ++ EK+ ++ EK+ ++ +K+ ++ EK+ +EE++
Sbjct: 1620 YVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKL 1679
Query: 391 WRQ-----------EEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEE----- 434
++ +K+ E ++ Q W++++ +E +E + EE W++EE
Sbjct: 1680 AKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEE 1739
Query: 435 --------KIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTW 486
K+ E EE + Q EKL E E K+ +EEE + +++EK+ + +EK+ E+EE+
Sbjct: 1740 GKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLG 1799
Query: 487 R-QEKLLKQEEKIWEQEEKMWRQEEKMWE------QEEKMQEQEEKMQRQEEKMREQEVR 539
R +E+L++++ K+ ++ E+ E++ + Q++ + ++++ + +++EK+ +++
Sbjct: 1800 RKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKEN 1859
Query: 540 LWQQEEKMQEQEVRLQELEERLG 562
L +E++ + +L +++ +LG
Sbjct: 1860 LLYNKERLTHSKKQLVQVKNKLG 1882
Score = 142 bits (359), Expect = 7e-34
Identities = 127/473 (26%), Positives = 242/473 (51%), Gaps = 47/473 (9%)
Query: 121 VSHVKKNSDEVKSSFKKRQEKMNEKNY--TFRKRVVIKKPWLRLGEVTAQKRPENSLLEE 178
++ +K +V+ S K+QEK+ ++ K +V K LR GE+ K + LE
Sbjct: 1909 LAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLR-GELDIAKEEKALNLEM 1967
Query: 179 TLHFDHAVRMGTYIEKLTKERDALSLELYRNTITDEELKEKNAELQEKL-----RLVESE 233
+ +R+ E L+K + + T ++EL E+ L+EK+ R++ E
Sbjct: 1968 KRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKILLHEDRILAME 2027
Query: 234 KSEIQLNVKDLKRKLE--RAQLLLPQQQ--LQVEADRLGKELQSVSAKLQAQVEENELWN 289
+SEI K KLE R Q + Q Q L + +L K+ +S+S E +L
Sbjct: 2028 ESEIA------KGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSK------EPAKLNK 2075
Query: 290 LLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMW 349
+L Q K+ R E K+ ++E KM + + + +E ++ ++ K+ +E E+ ++
Sbjct: 2076 ILKALQ--KLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELT 2133
Query: 350 RQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQ---- 405
+ E+K+ ++ K+ + +M +EEK+ E++ K+ + E+ +E+ EE+
Sbjct: 2134 KDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFL 2193
Query: 406 EKMWRQEKKMREQD---EKIREQEEEMWRQEEKIRELEEMMQDQE-------EKLREVEE 455
++ WR+ K+ + D EK Q +E+ +E E+E ++ + E E+ E EE
Sbjct: 2194 KRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREE 2253
Query: 456 KMQEEEEKMQEQEEKIQRQ---EEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKM 512
+ + EEE+++E+EE+ + + EEK E+EE+ +++K K++E++ E+EE +EE M
Sbjct: 2254 EEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIM 2313
Query: 513 WEQEEKM----QEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERL 561
E+E + +E+EE +EE RE+E+ +++ K+QEQ + ER+
Sbjct: 2314 SEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRRKSLRGRERV 2366
Score = 138 bits (347), Expect = 2e-32
Identities = 120/580 (20%), Positives = 285/580 (49%), Gaps = 40/580 (6%)
Query: 25 LSDEDSDLDFHINKLE--QQSKVRNKGHGKPREKSIADEKFFQLSEMEAYLENRKRRGTK 82
++ E+ D+ + ++ ++ V+ +G E++ + + + + + + R+ K
Sbjct: 1420 MTKEERDMSEEVEEMATLEEKVVKQEGKLVMIERTPSWQDWKKAWDEWKQVHGETRKSWK 1479
Query: 83 RWDEDDD---LEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSFKKRQ 139
W E+ + L+E E Q E L L +D+ ++ V +N + SS K Q
Sbjct: 1480 AWKEEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWEN---MLSSKSKEQ 1536
Query: 140 EKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKER 199
+ +E+ T + V R GE E + EE H + K +
Sbjct: 1537 QYKDEEEVTLEEEVS------REGE-----EKEQQVTEEQRHIQEEHKWARIHRKRARAE 1585
Query: 200 DALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQ 259
+ E + +E+L QE+ +L + E+ Q VK + E AQ Q
Sbjct: 1586 KKRAQEERKLAQEEEKLA------QEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQ 1639
Query: 260 LQVEADRLGKELQSVSAKL-QAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQEL 318
+ + G++L + KL Q + + + W EK+ R+EEK+ ++ K+ E +
Sbjct: 1640 KEETLAQRGEKLSQEAEKLAQKRKKLAKKW--------EKVAREEEKLAKKGGKLAEVKN 1691
Query: 319 KIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIRE 378
+ ++ E++ ++E+ + QE+++ ++ +++ E++ +EE++ ++E K+ +++K+ E
Sbjct: 1692 ILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAE 1751
Query: 379 QDEKIQEQEEEMWRQEEKIREQEE---KRQEKMWRQEKKMREQDEKIREQEEEMWRQEEK 435
++E + Q E++ +E K+ ++EE + +EK+ + ++KM E++E++ + E++ ++ K
Sbjct: 1752 EEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMK 1811
Query: 436 IRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQE 495
+ + E + E+L + + + +++ QE++ Q +E+ Q +E + +E+L +
Sbjct: 1812 LAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSK 1871
Query: 496 EKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQ 555
+++ + + K+ + + + EEK+ +++E + +++EK+ E E +L Q E+ + +++ +
Sbjct: 1872 KQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQ---E 1928
Query: 556 ELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELK 595
+L + KL + ++ G R G + L +E+K
Sbjct: 1929 KLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKALNLEMK 1968
Score = 133 bits (334), Expect = 6e-31
Identities = 124/568 (21%), Positives = 268/568 (47%), Gaps = 70/568 (12%)
Query: 131 VKSSFKKRQEKMNEKNYTFRKRVVIKK--PWLRLGEVTAQKRPENSLLEETLHFDHAVRM 188
+ S K E +N + TF + +++ + W E+ + E+ +L E L +D
Sbjct: 1254 ISGSQTKMSENLNAELVTFAQEMLVDRHPSWELFQEICPLLKKESKVLLEDLDWD----- 1308
Query: 189 GTYIEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKL 248
+ E+ + ++ I ++ ++ E+ ++ E+ + Q +D+ L
Sbjct: 1309 -----VVPPEKKPIFIQ--EGAIREDMIQGVTQEVIRHKEVMPREEEQAQKKARDMLG-L 1360
Query: 249 ERAQLLLPQQQLQVEAD----RLGKELQSVSAKLQAQVEENELWNLLNQQQE-----EKM 299
E Q++L + + + + +GKE+ K Q + + ++++ +M
Sbjct: 1361 EETQVILKKGKKVIFLEPGNVTMGKEISKKEEKKTFQKSPKQGRKAVQKERKVGKIKREM 1420
Query: 300 WRQEEKIQEQEEKMCEQELKIREQEEKM--------WRQEEKMHEQEEKIREQEDKMWRQ 351
++E + E+ E+M E K+ +QE K+ W+ +K ++ +++ + K W+
Sbjct: 1421 TKEERDMSEEVEEMATLEEKVVKQEGKLVMIERTPSWQDWKKAWDEWKQVHGETRKSWKA 1480
Query: 352 -----EEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQ--EEKIREQEEKR 404
E+++ ++EEK+ + EK+ +EE ++E + E+ +++W K +EQ+ K
Sbjct: 1481 WKEEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKD 1540
Query: 405 QEKMWRQEKKMREQDEKIRE--------QEEEMW--------RQEEKIRELEEMMQDQEE 448
+E++ +E+ RE +EK ++ QEE W R E+K + E + +EE
Sbjct: 1541 EEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEE 1600
Query: 449 KLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQE-EKIWEQEEKMWR 507
KL + E ++ +EE K+ + KI + + ++ + E K ++E+ L Q EK+ ++ EK+ +
Sbjct: 1601 KLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQ 1660
Query: 508 QEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKM---------QEQEV--RLQE 556
+ +K+ ++ EK+ +EEK+ ++ K+ E + L Q+ E++ QE+E+ L+E
Sbjct: 1661 KRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEE 1720
Query: 557 LEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQQY 616
LE + +L K E L +E G + E + + + L +++ +
Sbjct: 1721 LEWDMEELSWKEEEL---NQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELL 1777
Query: 617 VAAYQQLASGKEALPSCSSRKLRAKRWL 644
+ ++LA KE +P R R + L
Sbjct: 1778 IQEKEKLAQHKEKMPEEEERLGRKREQL 1805
Score = 118 bits (295), Expect = 2e-26
Identities = 126/566 (22%), Positives = 273/566 (48%), Gaps = 63/566 (11%)
Query: 51 GKPREKSIADE--------KFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKES 102
G+ +E+ + +E K+ ++ A E ++ + ++ ++++ E+ + +E
Sbjct: 1554 GEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEE 1613
Query: 103 LKR----VTFTLPDDEAIEDAG---------VSHVKKNSDEVKSSFKKRQEKMNEKNYTF 149
K V T D E + G +K S E + +KR++ +
Sbjct: 1614 RKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVA 1673
Query: 150 RKRVVIKKPWLRLGEVT---AQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDALSLEL 206
R+ + K +L EV AQK E E+ L + ++L +E + L ++
Sbjct: 1674 REEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQE--------KELAQELEELEWDM 1725
Query: 207 YRNTITDEELKEKNAEL-QEKLRLVESEKS-----------EIQLNVKDLKRKLERAQLL 254
+ +EEL ++ +L +EK +L E E++ E +L ++ E+ +L
Sbjct: 1726 EELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLA 1785
Query: 255 LPQQQLQVEADRLGKELQSVSAKLQAQVEENELW-NLLNQQQEEKMWRQEEKIQEQEEKM 313
++++ E +RLG++ + + K ++ E W N + + + KM ++K QE+K
Sbjct: 1786 QHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKN 1845
Query: 314 CEQEL-KIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQ 372
QE K+ +++E + +E++ ++++ + ++K+ + + + EEK+ +++E + ++
Sbjct: 1846 LAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKK 1905
Query: 373 EEKIREQDEKIQEQEEEMWRQEEKIREQEEK-RQEKMWRQEKKMREQDEKIREQEE---- 427
+EK+ E ++K+ + E+ + +++EK+ +++ K EK Q KK + I ++E+
Sbjct: 1906 KEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKALNL 1965
Query: 428 EMWR-QEEKIRELE--EMMQDQEEKLREVEEKMQEEEEKMQEQ----EEKIQRQEEKIQE 480
EM R EEK+R +E E + E + KM + E+++ E+ EEKI E++I
Sbjct: 1966 EMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKILLHEDRILA 2025
Query: 481 QEEKTWRQEKL-LKQEEKIWEQ-EEKMWRQEEKMWEQEEKMQEQEEKMQ---RQEEKMRE 535
EE + KL + ++I+ Q + K+ + K+ ++ E + ++ K+ + +K+
Sbjct: 2026 MEESEIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLNKILKALQKLTR 2085
Query: 536 QEVRLWQQEEKMQEQEVRLQELEERL 561
E +L Q+E KM + + L E RL
Sbjct: 2086 DERKLTQEEIKMTKMKRALFVKERRL 2111
Score = 110 bits (275), Expect = 4e-24
Identities = 134/602 (22%), Positives = 291/602 (48%), Gaps = 101/602 (16%)
Query: 54 REKSIADEKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDD 113
+++ +A EK M+ LE +G KR + D+ + E K +KR+
Sbjct: 1926 KQEKLAQEK------MKLALEKAMVQGKKRLRGELDIAKEE--KALNLEMKRL------- 1970
Query: 114 EAIEDAGVSHVKKNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPEN 173
A E + K+ + ++ RQ KM + +R + + + L E E+
Sbjct: 1971 -AEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKILLHEDRILAMEES 2029
Query: 174 SLLEETLHFDHAVR--------MGTYIEKLTKERDALSLELYRNTITDEELKEKNAELQE 225
+ + L F R + KL K+R++LS E + ++ LK ++
Sbjct: 2030 EIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAK---LNKILKALQKLTRD 2086
Query: 226 KLRLVESE----KSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQ 281
+ +L + E K + L VK+ + +E+++L + + + L K+ + ++ K +
Sbjct: 2087 ERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQRKL 2146
Query: 282 VEENELWNLLNQQQEEKMWRQEEKIQEQEEKMC---EQELKIREQE-----EKMWRQEEK 333
N++ ++N+ EEKM +E K+ + ++ E+E I E+E ++ WR+ ++
Sbjct: 2147 A--NKMRRMINK--EEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKE 2202
Query: 334 MH---EQEEKIREQEDKMWRQEEKIREQE---EKIREQEEKMWRQEEKIREQDEKIQEQE 387
+ +EK Q D++ +E E E +++ +QE +EE+ E++E
Sbjct: 2203 AKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEE------ 2256
Query: 388 EEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQE 447
R+EE++RE+EE+R+E+ +EK++ +++E+ +++++E +++E+++E EE+ +++E
Sbjct: 2257 ----REEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKE--KKKEEVQEKEEVFEEKE 2310
Query: 448 EKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEE--KIWEQEEKM 505
E + E EE E + ++EE EE+ EE+ R++++LK+E+ K+ EQ K
Sbjct: 2311 EIMSE------EETESLSDEEE-----EEESCSLEEEVDREKEILKKEKQFKLQEQRRKS 2359
Query: 506 WRQEEKMWE-------------QEEKMQEQEEKMQRQEEKMREQ-EVRLWQQEEKMQEQE 551
R E++ + ++ +K+ +M+E+ V + +++ ++++
Sbjct: 2360 LRGRERVLSILRGVPHGKGRAIRLGVLKSPLKKLMSTALEMKEKTPVPVPEKQISWEDKK 2419
Query: 552 VRLQELEER-LGKLGQKAELLG----------GAGRESGSQRL--PTLTPILQVELKSQE 598
+ E+ + LG + ++ E++G G ES +Q L P ++ IL+ ++++E
Sbjct: 2420 ATVVEIPRKFLGTMDKEREVMGKYEPIPPHVLGTVLESQAQDLKTPFMSHILRRTVEAEE 2479
Query: 599 AQ 600
Q
Sbjct: 2480 LQ 2481
>gi|194097392 Golgi autoantigen, golgin subfamily a, 2 [Homo
sapiens]
Length = 1002
Score = 146 bits (368), Expect = 7e-35
Identities = 126/491 (25%), Positives = 241/491 (49%), Gaps = 63/491 (12%)
Query: 191 YIEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLER 250
Y ++LTKERDAL LELY+NT ++E+LK++ +EL+EKLR++ +EK+ +QLN+++L++KLE
Sbjct: 285 YNKELTKERDALRLELYKNTQSNEDLKQEKSELEEKLRVLVTEKAGMQLNLEELQKKLEM 344
Query: 251 AQLLLPQQQLQVEADRLGKEL-QSVSAKLQAQVEENELWNLLNQQQEEK----------- 298
+LLL Q + EA ++L Q++ + Q + ++ + Q Q E+
Sbjct: 345 TELLLQQFSSRCEAPDANQQLQQAMEERAQLEAHLGQVMESVRQLQMERDKYAENLKGES 404
Query: 299 -MWRQE-EKIQEQ-----EEKMCE----QELKIREQEEKMWRQEEKMHEQEEKIREQEDK 347
MWRQ +++ EQ EEK C QEL+ E + E E E E +
Sbjct: 405 AMWRQRMQQMSEQVHTLREEKECSMSRVQELETSLAELRNQMAEPPPPEPPAGPSEVEQQ 464
Query: 348 MWRQEEKIREQEEKIREQEEKMWRQEEKI----REQDEKIQEQEE--EMWRQEEKIREQ- 400
+ + E +R++ E + Q + + E + REQ+E++ E E E+W ++ + R Q
Sbjct: 465 LQAEAEHLRKELEGLAGQLQAQVQDNEGLSRLNREQEERLLELERAAELWGEQAEARRQI 524
Query: 401 ---EEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKM 457
+ + + R + RE E++ E + + + E+ +Q ++ RE+ +K+
Sbjct: 525 LETMQNDRTTISRALSQNRELKEQLAELQSGFVKLTNENMEITSALQSEQHVKRELGKKL 584
Query: 458 QEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEE 517
E +EK+ E +E ++ + ++ Q +++ + L+Q ++Q E+++ +
Sbjct: 585 GELQEKLSELKETVELKSQEAQSLQQQRDQYLGHLQQYVAAYQQ----LTSEKEVLHNQL 640
Query: 518 KMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRE 577
+Q Q +Q+E + + +QE +QE + RL+ ++ +L + L+ G
Sbjct: 641 LLQTQLVDQLQQQEAQGKAVAEMARQE--LQETQERLEAATQQNQQLRAQLSLMAHPGEG 698
Query: 578 SGSQR---------------LPTLTPILQVELKSQEAQ---------SLQQQQDHYRGHL 613
G R +P P + +L+S+EA S +++Q RG L
Sbjct: 699 DGLDREEEEDEEEEEEEAVAVPQPMPSIPEDLESREAMVAFFNSAVASAEEEQARLRGQL 758
Query: 614 QQYVAAYQQLA 624
++ ++LA
Sbjct: 759 KEQRVRCRRLA 769
Score = 118 bits (296), Expect = 2e-26
Identities = 132/480 (27%), Positives = 225/480 (46%), Gaps = 85/480 (17%)
Query: 211 ITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKL------------ERAQLLLPQQ 258
IT E+LK++N E+ ++L E EK E L+ +L E+A+L
Sbjct: 182 ITIEKLKQQNQEITDQL---EEEKKECHQKQGALREQLQVHIQTIGILVSEKAELQTALA 238
Query: 259 QLQVEADRLGKELQSVSAKLQ-AQVEENELWNLLN--QQQEEKMWRQEEKIQEQEEKMCE 315
Q A + E + ++++LQ ++ EL L+ Q++K R +++ ++ + +
Sbjct: 239 HTQHAARQKEGESEDLASRLQYSRRRVGELERALSAVSTQQKKADRYNKELTKERDAL-R 297
Query: 316 QELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEK 375
EL Q + +QE+ E EEK+R + + + E ++K+ E + + +
Sbjct: 298 LELYKNTQSNEDLKQEKS--ELEEKLRVLVTEKAGMQLNLEELQKKLEMTELLLQQFSSR 355
Query: 376 IREQD--EKIQEQEEEMWRQE-------EKIREQEEKR---------QEKMWRQE-KKMR 416
D +++Q+ EE + E E +R+ + +R + MWRQ ++M
Sbjct: 356 CEAPDANQQLQQAMEERAQLEAHLGQVMESVRQLQMERDKYAENLKGESAMWRQRMQQMS 415
Query: 417 EQDEKIREQEE-EMWRQEEKIRELEEMMQDQEEKL--------REVEEKMQEEEEKMQEQ 467
EQ +RE++E M R +E L E+ E EVE+++Q E E ++++
Sbjct: 416 EQVHTLREEKECSMSRVQELETSLAELRNQMAEPPPPEPPAGPSEVEQQLQAEAEHLRKE 475
Query: 468 EEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEE--KMWRQEEKMWEQE-EKMQEQEE 524
E + Q + + E R + +QEE++ E E ++W ++ + Q E MQ
Sbjct: 476 LEGLAGQLQAQVQDNEGLSRLNR--EQEERLLELERAAELWGEQAEARRQILETMQNDRT 533
Query: 525 KMQR---QEEKMREQEVRLWQQEEKMQEQEVRL-----------QELEERLGKLGQKAEL 570
+ R Q +++EQ L K+ + + + +EL ++LG+L +K
Sbjct: 534 TISRALSQNRELKEQLAELQSGFVKLTNENMEITSALQSEQHVKRELGKKLGELQEKLSE 593
Query: 571 LGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQQYVAAYQQLASGKEAL 630
L +E+ VELKSQEAQSLQQQ+D Y GHLQQYVAAYQQL S KE L
Sbjct: 594 L----KET-------------VELKSQEAQSLQQQRDQYLGHLQQYVAAYQQLTSEKEVL 636
Score = 89.0 bits (219), Expect = 1e-17
Identities = 123/629 (19%), Positives = 271/629 (43%), Gaps = 64/629 (10%)
Query: 37 NKLEQQSKVRNKGHGKPREKS---------IADEKFFQLSEMEAYLENRKRRGTKRWDED 87
++LE++ K ++ G RE+ + EK +E++ L + + ++ E
Sbjct: 196 DQLEEEKKECHQKQGALREQLQVHIQTIGILVSEK----AELQTALAHTQHAARQKEGES 251
Query: 88 DDLEES-EDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSFKKRQE-----K 141
+DL + S++ L+R + + D + K D ++ K + K
Sbjct: 252 EDLASRLQYSRRRVGELERALSAVSTQQKKADRYNKELTKERDALRLELYKNTQSNEDLK 311
Query: 142 MNEKNYTFRKRVVI-KKPWLRLGEVTAQKRPENS--LLEETLHFDHAVRMGTYIEKLTKE 198
+ + RV++ +K ++L QK+ E + LL++ A +++ +E
Sbjct: 312 QEKSELEEKLRVLVTEKAGMQLNLEELQKKLEMTELLLQQFSSRCEAPDANQQLQQAMEE 371
Query: 199 RDALSLEL----------------YRNTITDEEL--KEKNAELQEKLRLVESEKSEIQLN 240
R L L Y + E +++ ++ E++ + EK
Sbjct: 372 RAQLEAHLGQVMESVRQLQMERDKYAENLKGESAMWRQRMQQMSEQVHTLREEKECSMSR 431
Query: 241 VKDLKRKLE--RAQLLLP------------QQQLQVEADRLGKELQSVSAKLQAQVEENE 286
V++L+ L R Q+ P +QQLQ EA+ L KEL+ ++ +LQAQV++NE
Sbjct: 432 VQELETSLAELRNQMAEPPPPEPPAGPSEVEQQLQAEAEHLRKELEGLAGQLQAQVQDNE 491
Query: 287 LWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQED 346
+ LN++QEE++ + E+ E + E +I E + + Q +++EQ
Sbjct: 492 GLSRLNREQEERLL-ELERAAELWGEQAEARRQILETMQNDRTTISRALSQNRELKEQLA 550
Query: 347 KMWRQEEKIREQEEKIRE--QEEKMWRQE--EKIREQDEKIQEQEEEMWRQEEKIREQEE 402
++ K+ + +I Q E+ ++E +K+ E EK+ E +E + + ++ + ++
Sbjct: 551 ELQSGFVKLTNENMEITSALQSEQHVKRELGKKLGELQEKLSELKETVELKSQEAQSLQQ 610
Query: 403 KRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462
+R + + ++ + +++ ++E + Q +L + +Q QE + + V E ++E +
Sbjct: 611 QRDQYLGHLQQYVAAY-QQLTSEKEVLHNQLLLQTQLVDQLQQQEAQGKAVAEMARQELQ 669
Query: 463 KMQEQEEKIQRQEEKIQEQEEKTWRQEKL----LKQEEKIWEQEEKMWRQEEKMWEQEEK 518
+ QE+ E +Q ++++ Q + ++EE E+EE+ + M E
Sbjct: 670 ETQERLEAATQQNQQLRAQLSLMAHPGEGDGLDREEEEDEEEEEEEAVAVPQPMPSIPED 729
Query: 519 MQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRES 578
++ +E + + E + +++EQ VR + L L ++ E A
Sbjct: 730 LESREAMVAFFNSAVASAEEEQARLRGQLKEQRVRCRRLAHLLASAQKEPEAAAPAPGTG 789
Query: 579 GSQRLPTLTPILQVELKSQEAQSLQQQQD 607
G LQ ++ +++ ++ Q+
Sbjct: 790 GDSVCGETHRALQGAMEKLQSRFMELMQE 818
Score = 46.6 bits (109), Expect = 7e-05
Identities = 66/330 (20%), Positives = 136/330 (41%), Gaps = 43/330 (13%)
Query: 194 KLTKERDALSLELYRNTITDEELKEKNAELQEKL----RLVESEKSEIQLNVKDLKRKLE 249
KLT E ++ L EL +K ELQEKL VE + E Q + + L
Sbjct: 558 KLTNENMEITSALQSEQHVKRELGKKLGELQEKLSELKETVELKSQEAQSLQQQRDQYLG 617
Query: 250 RAQ-LLLPQQQLQVEADRLGKEL----QSVSAKLQAQVEENELWNLLNQQQEEKMWRQEE 304
Q + QQL E + L +L Q V Q + + + + Q+ +E R E
Sbjct: 618 HLQQYVAAYQQLTSEKEVLHNQLLLQTQLVDQLQQQEAQGKAVAEMARQELQETQERLEA 677
Query: 305 KIQEQEEKMCEQELKIREQE-EKMWRQEEKMHEQEEK--------IREQEDKMWRQEEKI 355
Q+ ++ + L E + + R+EE+ E+EE+ + + + +E +
Sbjct: 678 ATQQNQQLRAQLSLMAHPGEGDGLDREEEEDEEEEEEEAVAVPQPMPSIPEDLESREAMV 737
Query: 356 REQEEKIREQEEKMWRQEEKIREQDEKIQE--------QEE-----------------EM 390
+ EE+ R +++EQ + + Q+E E
Sbjct: 738 AFFNSAVASAEEEQARLRGQLKEQRVRCRRLAHLLASAQKEPEAAAPAPGTGGDSVCGET 797
Query: 391 WRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKL 450
R + E+ + R ++ +++ ++E+ E++ + ++ + + I E + Q Q L
Sbjct: 798 HRALQGAMEKLQSRFMELMQEKADLKERVEELEHRCIQLSGETDTIGEYIALYQSQRAVL 857
Query: 451 REVEEKMQEEEEKMQEQEEKIQRQEEKIQE 480
+E + +E ++ + +E+++ + ++QE
Sbjct: 858 KERHREKEEYISRLAQDKEEMKVKLLELQE 887
Score = 41.6 bits (96), Expect = 0.002
Identities = 70/418 (16%), Positives = 174/418 (41%), Gaps = 52/418 (12%)
Query: 68 EMEAYLENRKRRGTKRWDEDDDLEESEDSKQC----KESLKRVTFTLPDDEAIEDAGVSH 123
+++A +++ + ++++ L E E + + E+ +++ T+ +D +S
Sbjct: 482 QLQAQVQDNEGLSRLNREQEERLLELERAAELWGEQAEARRQILETMQNDRTTISRALSQ 541
Query: 124 ---VKKNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETL 180
+K+ E++S F K + E + +K+ LG+ + + + S L+ET+
Sbjct: 542 NRELKEQLAELQSGFVKLTNENMEITSALQSEQHVKR---ELGKKLGELQEKLSELKETV 598
Query: 181 HFDHAVRMGTYIEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLN 240
+ L ++RD L + ++L + L +L L ++Q
Sbjct: 599 ELK-----SQEAQSLQQQRDQYLGHLQQYVAAYQQLTSEKEVLHNQLLLQTQLVDQLQQQ 653
Query: 241 VKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMW 300
K E A+ L + Q ++EA ++ Q + A+L E L +++E++
Sbjct: 654 EAQGKAVAEMARQELQETQERLEAAT--QQNQQLRAQLSLMAHPGEGDGLDREEEEDEEE 711
Query: 301 RQEEKIQ-EQEEKMCEQELKIREQ------------EEKMWRQEEKMHEQEEKIREQEDK 347
+EE + Q ++L+ RE EE+ R ++ EQ + R
Sbjct: 712 EEEEAVAVPQPMPSIPEDLESREAMVAFFNSAVASAEEEQARLRGQLKEQRVRCRRLAHL 771
Query: 348 MWRQEEK----------------------IREQEEKIREQEEKMWRQEEKIREQDEKIQE 385
+ +++ ++ EK++ + ++ +++ ++E+ E+++
Sbjct: 772 LASAQKEPEAAAPAPGTGGDSVCGETHRALQGAMEKLQSRFMELMQEKADLKERVEELEH 831
Query: 386 QEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMM 443
+ ++ + + I E Q + +++ RE++E I ++ + K+ EL+E++
Sbjct: 832 RCIQLSGETDTIGEYIALYQSQRAVLKERHREKEEYISRLAQDKEEMKVKLLELQELV 889
>gi|169208458 PREDICTED: similar to golgi autoantigen, golgin
subfamily a-like [Homo sapiens]
Length = 432
Score = 140 bits (353), Expect = 4e-33
Identities = 94/278 (33%), Positives = 166/278 (59%), Gaps = 32/278 (11%)
Query: 190 TYIEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKL- 248
T ++ L + L++ L ++ +L E L + E +K EI L V+ L R L
Sbjct: 82 TTLQDLESQYQELAVALDSSSAIISQLTENINSLVRTSK--EEKKHEIHL-VQKLGRSLF 138
Query: 249 ----ERAQLLLPQ--------QQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQE 296
+ A+ L PQ +QLQ E + L KEL+SV +LQA+VE N++ +LLN++QE
Sbjct: 139 KLKNQTAEPLAPQPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQE 198
Query: 297 EKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQE-----EKIREQEDKMWRQ 351
E++ QEE+++EQEE++CEQE ++ EQEE++ QEE++ EQE E++ E+ +K+ +Q
Sbjct: 199 ERLREQEERLREQEERLCEQEERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLKQ 258
Query: 352 EEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQE-----EKIREQE---EK 403
E + EQE + + E++ + E++ EQ E++++Q+E +W+QE E++RE E E
Sbjct: 259 ERRQEEQERLL--ERERLLDEVEELLEQ-ERLRQQDERLWQQETLRELERLRELERMLEL 315
Query: 404 RQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEE 441
E ++ Q + R E++ + + + E++++ELE+
Sbjct: 316 GWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELEK 353
Score = 108 bits (270), Expect = 2e-23
Identities = 78/266 (29%), Positives = 145/266 (54%), Gaps = 19/266 (7%)
Query: 330 QEEKMHEQEEKIREQEDKMWRQEEKIREQE-EKIREQEEKMWRQEEKIREQDEKIQEQEE 388
+EEK HE K+ R K++ Q E + Q + E+++++ ++++ E
Sbjct: 120 KEEKKHEIH-----LVQKLGRSLFKLKNQTAEPLAPQPPAGPSKVEQLQDETNHLRKELE 174
Query: 389 EMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEE 448
+ RQ + E + RQE+++REQ+E++REQEE + QEE++ E EE +++QEE
Sbjct: 175 SVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLCEQEERLCEQEERLREQEE 234
Query: 449 KLREVE-----EKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEE 503
+L E E E++ EE EK+ +QE + Q ++E++ E+E E+LL+Q E++ +Q+E
Sbjct: 235 RLCEQEKLPGQERLLEEVEKLLKQERR-QEEQERLLERERLLDEVEELLEQ-ERLRQQDE 292
Query: 504 KMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGK 563
++W+QE + E+++E E ++ E + EQ E++ + +LE+++ +
Sbjct: 293 RLWQQE--TLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKE 350
Query: 564 LGQKAELLGGAGRESGSQRLPTLTPI 589
L E GGA GS+ P+
Sbjct: 351 L----EKSGGAEEPRGSESAAAARPV 372
Score = 90.1 bits (222), Expect = 6e-18
Identities = 66/231 (28%), Positives = 126/231 (54%), Gaps = 32/231 (13%)
Query: 382 KIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQD------------EKIREQEEEM 429
++ E + R ++ ++ E +K+ R K++ Q K+ + ++E
Sbjct: 107 QLTENINSLVRTSKEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPQPPAGPSKVEQLQDET 166
Query: 430 WRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQ- 488
+++ + +Q + E + + + +EE+++EQEE+++ QEE++ EQEE+ Q
Sbjct: 167 NHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLCEQEERLCEQE 226
Query: 489 EKLLKQEEKIWEQE-----EKMWRQEEKMWEQEEKMQEQEEKMQR-----------QEEK 532
E+L +QEE++ EQE E++ + EK+ +QE + +EQE ++R ++E+
Sbjct: 227 ERLREQEERLCEQEKLPGQERLLEEVEKLLKQERRQEEQERLLERERLLDEVEELLEQER 286
Query: 533 MREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRL 583
+R+Q+ RLWQQ E ++E E RL+EL ER+ +LG +A A SG + L
Sbjct: 287 LRQQDERLWQQ-ETLRELE-RLREL-ERMLELGWEALYEQRAEPRSGFEEL 334
Score = 55.5 bits (132), Expect = 2e-07
Identities = 48/223 (21%), Positives = 108/223 (48%), Gaps = 24/223 (10%)
Query: 175 LLEETLHFDHAVR-MGTYIEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESE 233
L +ET H + +G ++ + LSL R E +E+ E +E+L E
Sbjct: 162 LQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLCEQEER 221
Query: 234 KSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQ 293
E + +++ + +L + L Q++L E ++L K+ + +
Sbjct: 222 LCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLKQER--------------------R 261
Query: 294 QQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEE 353
Q+E++ + E++ ++ E++ EQE ++R+Q+E++W+QE + E++RE E + E
Sbjct: 262 QEEQERLLERERLLDEVEELLEQE-RLRQQDERLWQQETL--RELERLRELERMLELGWE 318
Query: 354 KIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEK 396
+ EQ + R E++ + + + +++++E E+ +E +
Sbjct: 319 ALYEQRAEPRSGFEELNNENKSTLQLEQQVKELEKSGGAEEPR 361
>gi|154937324 hypothetical protein LOC440295 [Homo sapiens]
Length = 432
Score = 140 bits (353), Expect = 4e-33
Identities = 94/278 (33%), Positives = 166/278 (59%), Gaps = 32/278 (11%)
Query: 190 TYIEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKL- 248
T ++ L + L++ L ++ +L E L + E +K EI L V+ L R L
Sbjct: 82 TTLQDLESQYQELAVALDSSSAIISQLTENINSLVRTSK--EEKKHEIHL-VQKLGRSLF 138
Query: 249 ----ERAQLLLPQ--------QQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQE 296
+ A+ L PQ +QLQ E + L KEL+SV +LQA+VE N++ +LLN++QE
Sbjct: 139 KLKNQTAEPLAPQPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQE 198
Query: 297 EKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQE-----EKIREQEDKMWRQ 351
E++ QEE+++EQEE++CEQE ++ EQEE++ QEE++ EQE E++ E+ +K+ +Q
Sbjct: 199 ERLREQEERLREQEERLCEQEERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLKQ 258
Query: 352 EEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQE-----EKIREQE---EK 403
E + EQE + + E++ + E++ EQ E++++Q+E +W+QE E++RE E E
Sbjct: 259 ERRQEEQERLL--ERERLLDEVEELLEQ-ERLRQQDERLWQQETLRELERLRELERMLEL 315
Query: 404 RQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEE 441
E ++ Q + R E++ + + + E++++ELE+
Sbjct: 316 GWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELEK 353
Score = 108 bits (270), Expect = 2e-23
Identities = 78/266 (29%), Positives = 145/266 (54%), Gaps = 19/266 (7%)
Query: 330 QEEKMHEQEEKIREQEDKMWRQEEKIREQE-EKIREQEEKMWRQEEKIREQDEKIQEQEE 388
+EEK HE K+ R K++ Q E + Q + E+++++ ++++ E
Sbjct: 120 KEEKKHEIH-----LVQKLGRSLFKLKNQTAEPLAPQPPAGPSKVEQLQDETNHLRKELE 174
Query: 389 EMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEE 448
+ RQ + E + RQE+++REQ+E++REQEE + QEE++ E EE +++QEE
Sbjct: 175 SVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLCEQEERLCEQEERLREQEE 234
Query: 449 KLREVE-----EKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEE 503
+L E E E++ EE EK+ +QE + Q ++E++ E+E E+LL+Q E++ +Q+E
Sbjct: 235 RLCEQEKLPGQERLLEEVEKLLKQERR-QEEQERLLERERLLDEVEELLEQ-ERLRQQDE 292
Query: 504 KMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGK 563
++W+QE + E+++E E ++ E + EQ E++ + +LE+++ +
Sbjct: 293 RLWQQE--TLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKE 350
Query: 564 LGQKAELLGGAGRESGSQRLPTLTPI 589
L E GGA GS+ P+
Sbjct: 351 L----EKSGGAEEPRGSESAAAARPV 372
Score = 90.1 bits (222), Expect = 6e-18
Identities = 66/231 (28%), Positives = 126/231 (54%), Gaps = 32/231 (13%)
Query: 382 KIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQD------------EKIREQEEEM 429
++ E + R ++ ++ E +K+ R K++ Q K+ + ++E
Sbjct: 107 QLTENINSLVRTSKEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPQPPAGPSKVEQLQDET 166
Query: 430 WRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQ- 488
+++ + +Q + E + + + +EE+++EQEE+++ QEE++ EQEE+ Q
Sbjct: 167 NHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLCEQEERLCEQE 226
Query: 489 EKLLKQEEKIWEQE-----EKMWRQEEKMWEQEEKMQEQEEKMQR-----------QEEK 532
E+L +QEE++ EQE E++ + EK+ +QE + +EQE ++R ++E+
Sbjct: 227 ERLREQEERLCEQEKLPGQERLLEEVEKLLKQERRQEEQERLLERERLLDEVEELLEQER 286
Query: 533 MREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRL 583
+R+Q+ RLWQQ E ++E E RL+EL ER+ +LG +A A SG + L
Sbjct: 287 LRQQDERLWQQ-ETLRELE-RLREL-ERMLELGWEALYEQRAEPRSGFEEL 334
Score = 55.5 bits (132), Expect = 2e-07
Identities = 48/223 (21%), Positives = 108/223 (48%), Gaps = 24/223 (10%)
Query: 175 LLEETLHFDHAVR-MGTYIEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESE 233
L +ET H + +G ++ + LSL R E +E+ E +E+L E
Sbjct: 162 LQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLCEQEER 221
Query: 234 KSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQ 293
E + +++ + +L + L Q++L E ++L K+ + +
Sbjct: 222 LCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLKQER--------------------R 261
Query: 294 QQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEE 353
Q+E++ + E++ ++ E++ EQE ++R+Q+E++W+QE + E++RE E + E
Sbjct: 262 QEEQERLLERERLLDEVEELLEQE-RLRQQDERLWQQETL--RELERLRELERMLELGWE 318
Query: 354 KIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEK 396
+ EQ + R E++ + + + +++++E E+ +E +
Sbjct: 319 ALYEQRAEPRSGFEELNNENKSTLQLEQQVKELEKSGGAEEPR 361
>gi|169210281 PREDICTED: similar to M-phase phosphoprotein 10 (U3
small nucleolar ribonucleoprotein) [Homo sapiens]
Length = 213
Score = 140 bits (352), Expect = 5e-33
Identities = 79/143 (55%), Positives = 99/143 (69%), Gaps = 9/143 (6%)
Query: 1 MGGDNPEVSERA-NSSKFDPTKSPVLSDEDSDLDFHINKLEQQSKVRNKGHGKPREKSIA 59
MGGDNPEV ++A NSSKF+ KSPV SDEDSDLDF I+KLEQQSKV+N GHGKPREKSI
Sbjct: 63 MGGDNPEVGKKARNSSKFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSII 122
Query: 60 DEKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDA 119
DEKFFQLSEMEAYLENR++ ++ D DD+ +S + K+ V E+ ED
Sbjct: 123 DEKFFQLSEMEAYLENREKEEERKDDNDDESGKSSRNVNNKDFFDPV-------ESDEDI 175
Query: 120 GVSHVKK-NSDEVKSSFKKRQEK 141
H + S+++ KK+Q+K
Sbjct: 176 ASDHDDELGSNKMMKLLKKKQKK 198
Score = 35.8 bits (81), Expect = 0.13
Identities = 34/137 (24%), Positives = 61/137 (44%), Gaps = 6/137 (4%)
Query: 430 WRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQE 489
W+ E E EE Q+ EE E E QE+ E +QE+EE + E +K
Sbjct: 22 WQIVELGEESEE--QECEEDGSETETGGQEDLEDLQEEEEVSDMGGDN-PEVGKKARNSS 78
Query: 490 KLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQE---EK 546
K ++ ++ E+ + EQ+ K+Q R++ + E+ +L + E E
Sbjct: 79 KFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLEN 138
Query: 547 MQEQEVRLQELEERLGK 563
+++E R + ++ GK
Sbjct: 139 REKEEERKDDNDDESGK 155
>gi|169210488 PREDICTED: similar to M-phase phosphoprotein 10 (U3
small nucleolar ribonucleoprotein) [Homo sapiens]
Length = 213
Score = 140 bits (352), Expect = 5e-33
Identities = 79/143 (55%), Positives = 99/143 (69%), Gaps = 9/143 (6%)
Query: 1 MGGDNPEVSERA-NSSKFDPTKSPVLSDEDSDLDFHINKLEQQSKVRNKGHGKPREKSIA 59
MGGDNPEV ++A NSSKF+ KSPV SDEDSDLDF I+KLEQQSKV+N GHGKPREKSI
Sbjct: 63 MGGDNPEVGKKARNSSKFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSII 122
Query: 60 DEKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDA 119
DEKFFQLSEMEAYLENR++ ++ D DD+ +S + K+ V E+ ED
Sbjct: 123 DEKFFQLSEMEAYLENREKEEERKDDNDDESVKSSRNVNNKDFFDPV-------ESDEDI 175
Query: 120 GVSHVKK-NSDEVKSSFKKRQEK 141
H + S+++ KK+Q+K
Sbjct: 176 ASDHDDELGSNKMMKLLKKKQKK 198
Score = 33.5 bits (75), Expect = 0.64
Identities = 30/122 (24%), Positives = 54/122 (44%), Gaps = 3/122 (2%)
Query: 430 WRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQE 489
W+ E E EE Q+ EE E E QE+ E +QE+EE + E +K
Sbjct: 22 WQIVELGEESEE--QECEEDGSETETGGQEDLEDLQEEEEVSDMGGDN-PEVGKKARNSS 78
Query: 490 KLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQE 549
K ++ ++ E+ + EQ+ K+Q R++ + E+ +L + E ++
Sbjct: 79 KFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLEN 138
Query: 550 QE 551
+E
Sbjct: 139 RE 140
>gi|169210051 PREDICTED: similar to M-phase phosphoprotein 10 (U3
small nucleolar ribonucleoprotein) [Homo sapiens]
Length = 213
Score = 140 bits (352), Expect = 5e-33
Identities = 79/143 (55%), Positives = 99/143 (69%), Gaps = 9/143 (6%)
Query: 1 MGGDNPEVSERA-NSSKFDPTKSPVLSDEDSDLDFHINKLEQQSKVRNKGHGKPREKSIA 59
MGGDNPEV ++A NSSKF+ KSPV SDEDSDLDF I+KLEQQSKV+N GHGKPREKSI
Sbjct: 63 MGGDNPEVGKKARNSSKFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSII 122
Query: 60 DEKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDA 119
DEKFFQLSEMEAYLENR++ ++ D DD+ +S + K+ V E+ ED
Sbjct: 123 DEKFFQLSEMEAYLENREKEEERKDDNDDESGKSSRNVNNKDFFDPV-------ESDEDI 175
Query: 120 GVSHVKK-NSDEVKSSFKKRQEK 141
H + S+++ KK+Q+K
Sbjct: 176 ASDHDDELGSNKMMKLLKKKQKK 198
Score = 35.8 bits (81), Expect = 0.13
Identities = 34/137 (24%), Positives = 61/137 (44%), Gaps = 6/137 (4%)
Query: 430 WRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQE 489
W+ E E EE Q+ EE E E QE+ E +QE+EE + E +K
Sbjct: 22 WQIVELGEESEE--QECEEDGSETETGGQEDLEDLQEEEEVSDMGGDN-PEVGKKARNSS 78
Query: 490 KLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQE---EK 546
K ++ ++ E+ + EQ+ K+Q R++ + E+ +L + E E
Sbjct: 79 KFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLEN 138
Query: 547 MQEQEVRLQELEERLGK 563
+++E R + ++ GK
Sbjct: 139 REKEEERKDDNDDESGK 155
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sapiens]
Length = 1293
Score = 134 bits (337), Expect = 3e-31
Identities = 111/455 (24%), Positives = 231/455 (50%), Gaps = 70/455 (15%)
Query: 193 EKLTKERDALSL--------------ELYRNTITDEELKEKNAELQEKLRLVESEKSEIQ 238
E+LT++++ +L + Y + ++ +++ Q++L L+ + ++
Sbjct: 602 ERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTLK 661
Query: 239 LNVKDLKRKLERAQLLLPQQQLQVEADRLGK--ELQSVSAKLQAQVEENELWNLL----- 291
+ + D Q ++P V G ELQ +++ E +W+L
Sbjct: 662 MRISD--------QNIIPSVTRSVSVPDTGSIWELQPTASQPTVW-EGGSVWDLPLDTTT 712
Query: 292 -NQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQ--EDKM 348
E+ ++ K + E++ E E++ + +EE+ RQEE +QEE +R Q E++
Sbjct: 713 PGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERK 772
Query: 349 WRQEEKI--REQEEKIREQEEKMWRQEEKIREQ--DEKIQEQEEEMWRQEEKIREQEEKR 404
R+EE++ R+QEE +R Q E QE +R Q +E+ Q+QEE + R EE+ RE+EE+
Sbjct: 773 RREEEELARRKQEEALRRQRE----QEIALRRQREEEERQQQEEALRRLEERRREEEER- 827
Query: 405 QEKMWRQEKKMREQDEKIREQEEE--MWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462
R+Q+E +R+QEEE W +EE+ E + +++ ++ E +++ EEE
Sbjct: 828 -----------RKQEELLRKQEEEAAKWAREEE--EAQRRLEENRLRMEEEAARLRHEEE 874
Query: 463 KMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEK---M 519
+ + +E ++QRQ+E +++++++ +L +Q+++ +Q +M W Q+
Sbjct: 875 ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQ--QQLAQMKLPSSSTWGQQSNTTAC 932
Query: 520 QEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESG 579
Q Q + +K+ E+ R ++E++ Q++E+ ++ L+++ + QK G + SG
Sbjct: 933 QSQATLSLAEIQKLEEERERQLREEQRRQQREL-MKALQQQQQQQQQKLSGWGNVSKPSG 991
Query: 580 SQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQ 614
+ + +E++ +EA+ +Q+QQ + H Q
Sbjct: 992 TTK-------SLLEIQQEEARQMQKQQQQQQQHQQ 1019
Score = 110 bits (275), Expect = 4e-24
Identities = 82/258 (31%), Positives = 146/258 (56%), Gaps = 20/258 (7%)
Query: 378 EQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIR 437
+Q EK + + E R+E ++R + E+ + K RQE+ R+Q+E +R Q+EE E K R
Sbjct: 721 QQLEKAKAAKLEQERREAEMRAKREEEERK--RQEELRRQQEEILRRQQEE----ERKRR 774
Query: 438 ELEEMMQ-DQEEKLR-----EVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKL 491
E EE+ + QEE LR E+ + Q EEE+ Q+QEE ++R EE+ +E+EE+ ++E L
Sbjct: 775 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 834
Query: 492 LKQEEKI--W--EQEEKMWRQEE---KMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQE 544
KQEE+ W E+EE R EE +M E+ +++ +EE+ +R+E +++ Q+ L +Q
Sbjct: 835 RKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQK-ELMRQR 893
Query: 545 EKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQ 604
++ QE RLQ+ +++ K G++S + + + E++ E + +Q
Sbjct: 894 QQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQ 953
Query: 605 QQDHYRGHLQQYVAAYQQ 622
++ R ++ + A QQ
Sbjct: 954 LREEQRRQQRELMKALQQ 971
Score = 97.4 bits (241), Expect = 4e-20
Identities = 72/245 (29%), Positives = 133/245 (54%), Gaps = 22/245 (8%)
Query: 395 EKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMM---QDQEEKLR 451
E++++ E+ + K+ E++ RE + + + +EEE RQEE R+ EE++ Q++E K R
Sbjct: 718 EQLQQLEKAKAAKL---EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 774
Query: 452 EVEE---KMQEEEEKMQEQEE---KIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKM 505
E EE + QEE + Q ++E + QR+EE+ Q+QEE R E+ ++EE+ +QEE +
Sbjct: 775 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 834
Query: 506 WRQEEK--MWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGK 563
+QEE+ W +EE +E + +++ +M E+ RL +EE+ + +E+ +Q +E + +
Sbjct: 835 RKQEEEAAKWAREE--EEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQ 892
Query: 564 LGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQQYVAAYQQL 623
Q+ E L ++ Q+L Q++L S Q + +A Q+L
Sbjct: 893 RQQQQEALRRLQQQQQQQQL------AQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKL 946
Query: 624 ASGKE 628
+E
Sbjct: 947 EEERE 951
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sapiens]
Length = 1320
Score = 134 bits (337), Expect = 3e-31
Identities = 111/455 (24%), Positives = 231/455 (50%), Gaps = 70/455 (15%)
Query: 193 EKLTKERDALSL--------------ELYRNTITDEELKEKNAELQEKLRLVESEKSEIQ 238
E+LT++++ +L + Y + ++ +++ Q++L L+ + ++
Sbjct: 629 ERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTLK 688
Query: 239 LNVKDLKRKLERAQLLLPQQQLQVEADRLGK--ELQSVSAKLQAQVEENELWNLL----- 291
+ + D Q ++P V G ELQ +++ E +W+L
Sbjct: 689 MRISD--------QNIIPSVTRSVSVPDTGSIWELQPTASQPTVW-EGGSVWDLPLDTTT 739
Query: 292 -NQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQ--EDKM 348
E+ ++ K + E++ E E++ + +EE+ RQEE +QEE +R Q E++
Sbjct: 740 PGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERK 799
Query: 349 WRQEEKI--REQEEKIREQEEKMWRQEEKIREQ--DEKIQEQEEEMWRQEEKIREQEEKR 404
R+EE++ R+QEE +R Q E QE +R Q +E+ Q+QEE + R EE+ RE+EE+
Sbjct: 800 RREEEELARRKQEEALRRQRE----QEIALRRQREEEERQQQEEALRRLEERRREEEER- 854
Query: 405 QEKMWRQEKKMREQDEKIREQEEE--MWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462
R+Q+E +R+QEEE W +EE+ E + +++ ++ E +++ EEE
Sbjct: 855 -----------RKQEELLRKQEEEAAKWAREEE--EAQRRLEENRLRMEEEAARLRHEEE 901
Query: 463 KMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEK---M 519
+ + +E ++QRQ+E +++++++ +L +Q+++ +Q +M W Q+
Sbjct: 902 ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQ--QQLAQMKLPSSSTWGQQSNTTAC 959
Query: 520 QEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESG 579
Q Q + +K+ E+ R ++E++ Q++E+ ++ L+++ + QK G + SG
Sbjct: 960 QSQATLSLAEIQKLEEERERQLREEQRRQQREL-MKALQQQQQQQQQKLSGWGNVSKPSG 1018
Query: 580 SQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQ 614
+ + +E++ +EA+ +Q+QQ + H Q
Sbjct: 1019 TTK-------SLLEIQQEEARQMQKQQQQQQQHQQ 1046
Score = 110 bits (275), Expect = 4e-24
Identities = 82/258 (31%), Positives = 146/258 (56%), Gaps = 20/258 (7%)
Query: 378 EQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIR 437
+Q EK + + E R+E ++R + E+ + K RQE+ R+Q+E +R Q+EE E K R
Sbjct: 748 QQLEKAKAAKLEQERREAEMRAKREEEERK--RQEELRRQQEEILRRQQEE----ERKRR 801
Query: 438 ELEEMMQ-DQEEKLR-----EVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKL 491
E EE+ + QEE LR E+ + Q EEE+ Q+QEE ++R EE+ +E+EE+ ++E L
Sbjct: 802 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 861
Query: 492 LKQEEKI--W--EQEEKMWRQEE---KMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQE 544
KQEE+ W E+EE R EE +M E+ +++ +EE+ +R+E +++ Q+ L +Q
Sbjct: 862 RKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQK-ELMRQR 920
Query: 545 EKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQ 604
++ QE RLQ+ +++ K G++S + + + E++ E + +Q
Sbjct: 921 QQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQ 980
Query: 605 QQDHYRGHLQQYVAAYQQ 622
++ R ++ + A QQ
Sbjct: 981 LREEQRRQQRELMKALQQ 998
Score = 97.4 bits (241), Expect = 4e-20
Identities = 72/245 (29%), Positives = 133/245 (54%), Gaps = 22/245 (8%)
Query: 395 EKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMM---QDQEEKLR 451
E++++ E+ + K+ E++ RE + + + +EEE RQEE R+ EE++ Q++E K R
Sbjct: 745 EQLQQLEKAKAAKL---EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 801
Query: 452 EVEE---KMQEEEEKMQEQEE---KIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKM 505
E EE + QEE + Q ++E + QR+EE+ Q+QEE R E+ ++EE+ +QEE +
Sbjct: 802 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 861
Query: 506 WRQEEK--MWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGK 563
+QEE+ W +EE +E + +++ +M E+ RL +EE+ + +E+ +Q +E + +
Sbjct: 862 RKQEEEAAKWAREE--EEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQ 919
Query: 564 LGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQQYVAAYQQL 623
Q+ E L ++ Q+L Q++L S Q + +A Q+L
Sbjct: 920 RQQQQEALRRLQQQQQQQQL------AQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKL 973
Query: 624 ASGKE 628
+E
Sbjct: 974 EEERE 978
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sapiens]
Length = 1299
Score = 134 bits (337), Expect = 3e-31
Identities = 111/455 (24%), Positives = 231/455 (50%), Gaps = 70/455 (15%)
Query: 193 EKLTKERDALSL--------------ELYRNTITDEELKEKNAELQEKLRLVESEKSEIQ 238
E+LT++++ +L + Y + ++ +++ Q++L L+ + ++
Sbjct: 608 ERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTLK 667
Query: 239 LNVKDLKRKLERAQLLLPQQQLQVEADRLGK--ELQSVSAKLQAQVEENELWNLL----- 291
+ + D Q ++P V G ELQ +++ E +W+L
Sbjct: 668 MRISD--------QNIIPSVTRSVSVPDTGSIWELQPTASQPTVW-EGGSVWDLPLDTTT 718
Query: 292 -NQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQ--EDKM 348
E+ ++ K + E++ E E++ + +EE+ RQEE +QEE +R Q E++
Sbjct: 719 PGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERK 778
Query: 349 WRQEEKI--REQEEKIREQEEKMWRQEEKIREQ--DEKIQEQEEEMWRQEEKIREQEEKR 404
R+EE++ R+QEE +R Q E QE +R Q +E+ Q+QEE + R EE+ RE+EE+
Sbjct: 779 RREEEELARRKQEEALRRQRE----QEIALRRQREEEERQQQEEALRRLEERRREEEER- 833
Query: 405 QEKMWRQEKKMREQDEKIREQEEE--MWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462
R+Q+E +R+QEEE W +EE+ E + +++ ++ E +++ EEE
Sbjct: 834 -----------RKQEELLRKQEEEAAKWAREEE--EAQRRLEENRLRMEEEAARLRHEEE 880
Query: 463 KMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEK---M 519
+ + +E ++QRQ+E +++++++ +L +Q+++ +Q +M W Q+
Sbjct: 881 ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQ--QQLAQMKLPSSSTWGQQSNTTAC 938
Query: 520 QEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESG 579
Q Q + +K+ E+ R ++E++ Q++E+ ++ L+++ + QK G + SG
Sbjct: 939 QSQATLSLAEIQKLEEERERQLREEQRRQQREL-MKALQQQQQQQQQKLSGWGNVSKPSG 997
Query: 580 SQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQ 614
+ + +E++ +EA+ +Q+QQ + H Q
Sbjct: 998 TTK-------SLLEIQQEEARQMQKQQQQQQQHQQ 1025
Score = 110 bits (275), Expect = 4e-24
Identities = 82/258 (31%), Positives = 146/258 (56%), Gaps = 20/258 (7%)
Query: 378 EQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIR 437
+Q EK + + E R+E ++R + E+ + K RQE+ R+Q+E +R Q+EE E K R
Sbjct: 727 QQLEKAKAAKLEQERREAEMRAKREEEERK--RQEELRRQQEEILRRQQEE----ERKRR 780
Query: 438 ELEEMMQ-DQEEKLR-----EVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKL 491
E EE+ + QEE LR E+ + Q EEE+ Q+QEE ++R EE+ +E+EE+ ++E L
Sbjct: 781 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 840
Query: 492 LKQEEKI--W--EQEEKMWRQEE---KMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQE 544
KQEE+ W E+EE R EE +M E+ +++ +EE+ +R+E +++ Q+ L +Q
Sbjct: 841 RKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQK-ELMRQR 899
Query: 545 EKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQ 604
++ QE RLQ+ +++ K G++S + + + E++ E + +Q
Sbjct: 900 QQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQ 959
Query: 605 QQDHYRGHLQQYVAAYQQ 622
++ R ++ + A QQ
Sbjct: 960 LREEQRRQQRELMKALQQ 977
Score = 97.4 bits (241), Expect = 4e-20
Identities = 72/245 (29%), Positives = 133/245 (54%), Gaps = 22/245 (8%)
Query: 395 EKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMM---QDQEEKLR 451
E++++ E+ + K+ E++ RE + + + +EEE RQEE R+ EE++ Q++E K R
Sbjct: 724 EQLQQLEKAKAAKL---EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 780
Query: 452 EVEE---KMQEEEEKMQEQEE---KIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKM 505
E EE + QEE + Q ++E + QR+EE+ Q+QEE R E+ ++EE+ +QEE +
Sbjct: 781 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 840
Query: 506 WRQEEK--MWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGK 563
+QEE+ W +EE +E + +++ +M E+ RL +EE+ + +E+ +Q +E + +
Sbjct: 841 RKQEEEAAKWAREE--EEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQ 898
Query: 564 LGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQQYVAAYQQL 623
Q+ E L ++ Q+L Q++L S Q + +A Q+L
Sbjct: 899 RQQQQEALRRLQQQQQQQQL------AQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKL 952
Query: 624 ASGKE 628
+E
Sbjct: 953 EEERE 957
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapiens]
Length = 1299
Score = 134 bits (337), Expect = 3e-31
Identities = 111/455 (24%), Positives = 231/455 (50%), Gaps = 70/455 (15%)
Query: 193 EKLTKERDALSL--------------ELYRNTITDEELKEKNAELQEKLRLVESEKSEIQ 238
E+LT++++ +L + Y + ++ +++ Q++L L+ + ++
Sbjct: 608 ERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTLK 667
Query: 239 LNVKDLKRKLERAQLLLPQQQLQVEADRLGK--ELQSVSAKLQAQVEENELWNLL----- 291
+ + D Q ++P V G ELQ +++ E +W+L
Sbjct: 668 MRISD--------QNIIPSVTRSVSVPDTGSIWELQPTASQPTVW-EGGSVWDLPLDTTT 718
Query: 292 -NQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQ--EDKM 348
E+ ++ K + E++ E E++ + +EE+ RQEE +QEE +R Q E++
Sbjct: 719 PGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERK 778
Query: 349 WRQEEKI--REQEEKIREQEEKMWRQEEKIREQ--DEKIQEQEEEMWRQEEKIREQEEKR 404
R+EE++ R+QEE +R Q E QE +R Q +E+ Q+QEE + R EE+ RE+EE+
Sbjct: 779 RREEEELARRKQEEALRRQRE----QEIALRRQREEEERQQQEEALRRLEERRREEEER- 833
Query: 405 QEKMWRQEKKMREQDEKIREQEEE--MWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462
R+Q+E +R+QEEE W +EE+ E + +++ ++ E +++ EEE
Sbjct: 834 -----------RKQEELLRKQEEEAAKWAREEE--EAQRRLEENRLRMEEEAARLRHEEE 880
Query: 463 KMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEK---M 519
+ + +E ++QRQ+E +++++++ +L +Q+++ +Q +M W Q+
Sbjct: 881 ERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQ--QQLAQMKLPSSSTWGQQSNTTAC 938
Query: 520 QEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESG 579
Q Q + +K+ E+ R ++E++ Q++E+ ++ L+++ + QK G + SG
Sbjct: 939 QSQATLSLAEIQKLEEERERQLREEQRRQQREL-MKALQQQQQQQQQKLSGWGNVSKPSG 997
Query: 580 SQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQ 614
+ + +E++ +EA+ +Q+QQ + H Q
Sbjct: 998 TTK-------SLLEIQQEEARQMQKQQQQQQQHQQ 1025
Score = 110 bits (275), Expect = 4e-24
Identities = 82/258 (31%), Positives = 146/258 (56%), Gaps = 20/258 (7%)
Query: 378 EQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIR 437
+Q EK + + E R+E ++R + E+ + K RQE+ R+Q+E +R Q+EE E K R
Sbjct: 727 QQLEKAKAAKLEQERREAEMRAKREEEERK--RQEELRRQQEEILRRQQEE----ERKRR 780
Query: 438 ELEEMMQ-DQEEKLR-----EVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKL 491
E EE+ + QEE LR E+ + Q EEE+ Q+QEE ++R EE+ +E+EE+ ++E L
Sbjct: 781 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 840
Query: 492 LKQEEKI--W--EQEEKMWRQEE---KMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQE 544
KQEE+ W E+EE R EE +M E+ +++ +EE+ +R+E +++ Q+ L +Q
Sbjct: 841 RKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQK-ELMRQR 899
Query: 545 EKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQ 604
++ QE RLQ+ +++ K G++S + + + E++ E + +Q
Sbjct: 900 QQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQ 959
Query: 605 QQDHYRGHLQQYVAAYQQ 622
++ R ++ + A QQ
Sbjct: 960 LREEQRRQQRELMKALQQ 977
Score = 97.4 bits (241), Expect = 4e-20
Identities = 72/245 (29%), Positives = 133/245 (54%), Gaps = 22/245 (8%)
Query: 395 EKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMM---QDQEEKLR 451
E++++ E+ + K+ E++ RE + + + +EEE RQEE R+ EE++ Q++E K R
Sbjct: 724 EQLQQLEKAKAAKL---EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRR 780
Query: 452 EVEE---KMQEEEEKMQEQEE---KIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKM 505
E EE + QEE + Q ++E + QR+EE+ Q+QEE R E+ ++EE+ +QEE +
Sbjct: 781 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 840
Query: 506 WRQEEK--MWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGK 563
+QEE+ W +EE +E + +++ +M E+ RL +EE+ + +E+ +Q +E + +
Sbjct: 841 RKQEEEAAKWAREE--EEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQ 898
Query: 564 LGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQQYVAAYQQL 623
Q+ E L ++ Q+L Q++L S Q + +A Q+L
Sbjct: 899 RQQQQEALRRLQQQQQQQQL------AQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKL 952
Query: 624 ASGKE 628
+E
Sbjct: 953 EEERE 957
>gi|239745259 PREDICTED: hypothetical protein isoform 2 [Homo
sapiens]
Length = 432
Score = 134 bits (337), Expect = 3e-31
Identities = 92/278 (33%), Positives = 164/278 (58%), Gaps = 32/278 (11%)
Query: 190 TYIEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKL- 248
T ++ L + L++ L ++ +L E L + E +K EI L V+ L R L
Sbjct: 82 TTLQDLESQYQELAVALDSSSAIISQLTENINSLVRTSK--EEKKHEIHL-VQKLGRSLF 138
Query: 249 ----ERAQLLLPQ--------QQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQE 296
+ A+ L P+ +QLQ E + L KEL+SV +LQA+VE N++ +LLN++QE
Sbjct: 139 KLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQE 198
Query: 297 EKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQE-----EKIREQEDKMWRQ 351
E++ QEE+++EQEE++ EQE ++ EQEE++ QEE++ EQE E++ E+ +K+ Q
Sbjct: 199 ERLREQEERLREQEERLHEQEERLCEQEERLCEQEERLCEQEKLPGQERLLEEVEKLLEQ 258
Query: 352 EEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQE-----EKIREQE---EK 403
E + EQE + + E++ + E++ EQ E++++Q+E +W+QE E++RE E E
Sbjct: 259 ERRQEEQERLL--ERERLLDEVEELLEQ-ERLRQQDERLWQQETLRELERLRELERMLEL 315
Query: 404 RQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEE 441
E ++ Q + R E++ + + + E++++ELE+
Sbjct: 316 GWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELEK 353
Score = 98.6 bits (244), Expect = 2e-20
Identities = 80/285 (28%), Positives = 154/285 (54%), Gaps = 35/285 (12%)
Query: 258 QQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQE 317
Q L+ + L L S SA + +Q+ EN + +L+ +EEK + E + + K+
Sbjct: 85 QDLESQYQELAVALDSSSAII-SQLTEN-INSLVRTSKEEK--KHEIHLVQ---KLGRSL 137
Query: 318 LKIREQEEKMWRQE--------EKMHEQEEKIREQEDKMWRQEEKI-----------REQ 358
K++ Q + E E++ ++ +R++ + + RQ + R Q
Sbjct: 138 FKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQ 197
Query: 359 EEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEE-KRQEKMWRQEKKMRE 417
EE++REQEE++ QEE++ EQ+E++ EQEE + QEE++ EQE+ QE++ + +K+ E
Sbjct: 198 EERLREQEERLREQEERLHEQEERLCEQEERLCEQEERLCEQEKLPGQERLLEEVEKLLE 257
Query: 418 QDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEE-----EKMQEQEEKIQ 472
Q E+ +E++E + +E + E+EE++ ++E+LR+ +E++ ++E E+++E E ++
Sbjct: 258 Q-ERRQEEQERLLERERLLDEVEELL--EQERLRQQDERLWQQETLRELERLRELERMLE 314
Query: 473 RQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEE 517
E + EQ + + L E K Q E+ ++ EK EE
Sbjct: 315 LGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELEKSGGAEE 359
Score = 93.2 bits (230), Expect = 7e-19
Identities = 67/231 (29%), Positives = 126/231 (54%), Gaps = 32/231 (13%)
Query: 382 KIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQD------------EKIREQEEEM 429
++ E + R ++ ++ E +K+ R K++ Q K+ + ++E
Sbjct: 107 QLTENINSLVRTSKEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDET 166
Query: 430 WRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQ- 488
+++ + +Q + E + + + +EE+++EQEE+++ QEE++ EQEE+ Q
Sbjct: 167 NHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLHEQEERLCEQE 226
Query: 489 EKLLKQEEKIWEQE-----EKMWRQEEKMWEQEEKMQEQEEKMQR-----------QEEK 532
E+L +QEE++ EQE E++ + EK+ EQE + +EQE ++R ++E+
Sbjct: 227 ERLCEQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLDEVEELLEQER 286
Query: 533 MREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRL 583
+R+Q+ RLWQQ E ++E E RL+EL ER+ +LG +A A SG + L
Sbjct: 287 LRQQDERLWQQ-ETLRELE-RLREL-ERMLELGWEALYEQRAEPRSGFEEL 334
Score = 53.5 bits (127), Expect = 6e-07
Identities = 48/234 (20%), Positives = 104/234 (44%), Gaps = 48/234 (20%)
Query: 175 LLEETLHFDHAVR-MGTYIEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESE 233
L +ET H + +G ++ + LSL R E +E+ E +E+L E
Sbjct: 162 LQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLHEQEER 221
Query: 234 KSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQ 293
E + + + + +L + L Q++L E ++L
Sbjct: 222 LCEQEERLCEQEERLCEQEKLPGQERLLEEVEKL-------------------------- 255
Query: 294 QQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQE- 352
++E+ QE++E++ E+E + E EE + ++E++R+Q++++W+QE
Sbjct: 256 -------LEQERRQEEQERLLERERLLDEVEELL---------EQERLRQQDERLWQQET 299
Query: 353 ----EKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEE 402
E++RE E + E ++ Q + R E++ + + + E++++E E+
Sbjct: 300 LRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELEK 353
Score = 50.1 bits (118), Expect = 7e-06
Identities = 46/184 (25%), Positives = 94/184 (51%), Gaps = 22/184 (11%)
Query: 193 EKLTKERDALSLELYRNTITDEELKEKNAEL-QEKLRLVESEKSEIQLNVKDLKRKLERA 251
E+L ++ + L + R +E L E+ L +++ RL E EK Q +R LE
Sbjct: 199 ERLREQEERLREQEERLHEQEERLCEQEERLCEQEERLCEQEKLPGQ------ERLLEEV 252
Query: 252 QLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEE 311
+ LL Q++ Q E +RL E + + +++ +E+ L +QQ+E++W Q+E ++E E
Sbjct: 253 EKLLEQERRQEEQERL-LERERLLDEVEELLEQERL-----RQQDERLW-QQETLRELE- 304
Query: 312 KMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWR 371
++RE E + E ++EQ + R +++ + + + E++++E E+
Sbjct: 305 -------RLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELEKSGGA 357
Query: 372 QEEK 375
+E +
Sbjct: 358 EEPR 361
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.306 0.124 0.335
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,549,515
Number of Sequences: 37866
Number of extensions: 1709028
Number of successful extensions: 159417
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1821
Number of HSP's successfully gapped in prelim test: 1272
Number of HSP's that attempted gapping in prelim test: 15552
Number of HSP's gapped (non-prelim): 33818
length of query: 655
length of database: 18,247,518
effective HSP length: 109
effective length of query: 546
effective length of database: 14,120,124
effective search space: 7709587704
effective search space used: 7709587704
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.