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Search of human proteins with 116805330
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|116805330 small conductance calcium-activated potassium
channel protein 3 isoform a [Homo sapiens]
(731 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|116805330 small conductance calcium-activated potassium chann... 1463 0.0
gi|25777650 small conductance calcium-activated potassium channe... 828 0.0
gi|25777645 small conductance calcium-activated potassium channe... 816 0.0
gi|25777643 potassium intermediate/small conductance calcium-act... 698 0.0
gi|4504859 intermediate conductance calcium-activated potassium ... 340 2e-93
gi|25777647 small conductance calcium-activated potassium channe... 335 9e-92
gi|33286444 mastermind-like 2 [Homo sapiens] 65 2e-10
gi|114431236 zinc finger protein 462 [Homo sapiens] 63 8e-10
gi|110347429 mediator complex subunit 12 [Homo sapiens] 62 2e-09
gi|17017963 forkhead box P2 isoform I [Homo sapiens] 62 2e-09
gi|22538413 forkhead box P2 isoform III [Homo sapiens] 62 2e-09
gi|149999352 forkhead box P2 isoform II [Homo sapiens] 62 2e-09
gi|157743257 POU domain, class 6, transcription factor 2 [Homo s... 62 2e-09
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 60 9e-09
gi|27886520 nuclear factor of activated T-cells 5 isoform a [Hom... 59 1e-08
gi|5729945 nuclear factor of activated T-cells 5 isoform c [Homo... 59 1e-08
gi|164419746 nuclear factor of activated T-cells 5 isoform d [Ho... 59 1e-08
gi|164419744 nuclear factor of activated T-cells 5 isoform b [Ho... 59 1e-08
gi|27886524 nuclear factor of activated T-cells 5 isoform a [Hom... 59 1e-08
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)... 59 2e-08
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)... 59 2e-08
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)... 59 2e-08
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 58 3e-08
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 58 3e-08
gi|4507379 TATA box binding protein [Homo sapiens] 57 8e-08
gi|32307128 nuclear receptor coactivator 6 [Homo sapiens] 57 8e-08
gi|187829452 autism susceptibility candidate 2 isoform 2 [Homo s... 55 2e-07
gi|17864090 autism susceptibility candidate 2 isoform 1 [Homo sa... 55 2e-07
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] 55 2e-07
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] 55 2e-07
>gi|116805330 small conductance calcium-activated potassium channel
protein 3 isoform a [Homo sapiens]
Length = 731
Score = 1463 bits (3788), Expect = 0.0
Identities = 731/731 (100%), Positives = 731/731 (100%)
Query: 1 MDTSGHFHDSGVGDLDEDPKCPCPSSGDEQQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQ 60
MDTSGHFHDSGVGDLDEDPKCPCPSSGDEQQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQ
Sbjct: 1 MDTSGHFHDSGVGDLDEDPKCPCPSSGDEQQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQ 60
Query: 61 PQPPQLQQQQQQQQQQQQQQPPHPLSQLAQLQSQPVHPGLLHSSPTAFRAPPSSNSTAIL 120
PQPPQLQQQQQQQQQQQQQQPPHPLSQLAQLQSQPVHPGLLHSSPTAFRAPPSSNSTAIL
Sbjct: 61 PQPPQLQQQQQQQQQQQQQQPPHPLSQLAQLQSQPVHPGLLHSSPTAFRAPPSSNSTAIL 120
Query: 121 HPSSRQGSQLNLNDHLLGHSPSSTATSGPGGGSRHRQASPLVHRRDSNPFTEIAMSSCKY 180
HPSSRQGSQLNLNDHLLGHSPSSTATSGPGGGSRHRQASPLVHRRDSNPFTEIAMSSCKY
Sbjct: 121 HPSSRQGSQLNLNDHLLGHSPSSTATSGPGGGSRHRQASPLVHRRDSNPFTEIAMSSCKY 180
Query: 181 SGGVMKPLSRLSASRRNLIEAETEGQPLQLFSPSNPPEIVISSREDNHAHQTLLHHPNAT 240
SGGVMKPLSRLSASRRNLIEAETEGQPLQLFSPSNPPEIVISSREDNHAHQTLLHHPNAT
Sbjct: 181 SGGVMKPLSRLSASRRNLIEAETEGQPLQLFSPSNPPEIVISSREDNHAHQTLLHHPNAT 240
Query: 241 HNHQHAGTTASSTTFPKANKRKNQNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVI 300
HNHQHAGTTASSTTFPKANKRKNQNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVI
Sbjct: 241 HNHQHAGTTASSTTFPKANKRKNQNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVI 300
Query: 301 ETELSWGLYSKDSMFSLALKCLISLSTIILLGLIIAYHTREVQLFVIDNGADDWRIAMTY 360
ETELSWGLYSKDSMFSLALKCLISLSTIILLGLIIAYHTREVQLFVIDNGADDWRIAMTY
Sbjct: 301 ETELSWGLYSKDSMFSLALKCLISLSTIILLGLIIAYHTREVQLFVIDNGADDWRIAMTY 360
Query: 361 ERILYISLEMLVCAIHPIPGEYKFFWTARLAFSYTPSRAEADVDIILSIPMFLRLYLIAR 420
ERILYISLEMLVCAIHPIPGEYKFFWTARLAFSYTPSRAEADVDIILSIPMFLRLYLIAR
Sbjct: 361 ERILYISLEMLVCAIHPIPGEYKFFWTARLAFSYTPSRAEADVDIILSIPMFLRLYLIAR 420
Query: 421 VMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRV 480
VMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRV
Sbjct: 421 VMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRV 480
Query: 481 CERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVA 540
CERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVA
Sbjct: 481 CERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVA 540
Query: 541 VVARKLELTKAEKHVHNFMMDTQLTKRIKNAAANVLRETWLIYKHTKLLKKIDHAKVRKH 600
VVARKLELTKAEKHVHNFMMDTQLTKRIKNAAANVLRETWLIYKHTKLLKKIDHAKVRKH
Sbjct: 541 VVARKLELTKAEKHVHNFMMDTQLTKRIKNAAANVLRETWLIYKHTKLLKKIDHAKVRKH 600
Query: 601 QRKFLQAIHQLRSVKMEQRKLSDQANTLVDLSKMQNVMYDLITELNDRSEDLEKQIGSLE 660
QRKFLQAIHQLRSVKMEQRKLSDQANTLVDLSKMQNVMYDLITELNDRSEDLEKQIGSLE
Sbjct: 601 QRKFLQAIHQLRSVKMEQRKLSDQANTLVDLSKMQNVMYDLITELNDRSEDLEKQIGSLE 660
Query: 661 SKLEHLTASFNSLPLLIADTLRQQQQQLLSAIIEARGVSVAVGTTHTPISDSPIGVSSTS 720
SKLEHLTASFNSLPLLIADTLRQQQQQLLSAIIEARGVSVAVGTTHTPISDSPIGVSSTS
Sbjct: 661 SKLEHLTASFNSLPLLIADTLRQQQQQLLSAIIEARGVSVAVGTTHTPISDSPIGVSSTS 720
Query: 721 FPTPYTSSSSC 731
FPTPYTSSSSC
Sbjct: 721 FPTPYTSSSSC 731
>gi|25777650 small conductance calcium-activated potassium channel
protein 3 isoform b [Homo sapiens]
Length = 426
Score = 828 bits (2138), Expect = 0.0
Identities = 421/421 (100%), Positives = 421/421 (100%)
Query: 311 KDSMFSLALKCLISLSTIILLGLIIAYHTREVQLFVIDNGADDWRIAMTYERILYISLEM 370
KDSMFSLALKCLISLSTIILLGLIIAYHTREVQLFVIDNGADDWRIAMTYERILYISLEM
Sbjct: 6 KDSMFSLALKCLISLSTIILLGLIIAYHTREVQLFVIDNGADDWRIAMTYERILYISLEM 65
Query: 371 LVCAIHPIPGEYKFFWTARLAFSYTPSRAEADVDIILSIPMFLRLYLIARVMLLHSKLFT 430
LVCAIHPIPGEYKFFWTARLAFSYTPSRAEADVDIILSIPMFLRLYLIARVMLLHSKLFT
Sbjct: 66 LVCAIHPIPGEYKFFWTARLAFSYTPSRAEADVDIILSIPMFLRLYLIARVMLLHSKLFT 125
Query: 431 DASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRVCERYHDQQDV 490
DASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRVCERYHDQQDV
Sbjct: 126 DASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRVCERYHDQQDV 185
Query: 491 TSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTK 550
TSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTK
Sbjct: 186 TSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTK 245
Query: 551 AEKHVHNFMMDTQLTKRIKNAAANVLRETWLIYKHTKLLKKIDHAKVRKHQRKFLQAIHQ 610
AEKHVHNFMMDTQLTKRIKNAAANVLRETWLIYKHTKLLKKIDHAKVRKHQRKFLQAIHQ
Sbjct: 246 AEKHVHNFMMDTQLTKRIKNAAANVLRETWLIYKHTKLLKKIDHAKVRKHQRKFLQAIHQ 305
Query: 611 LRSVKMEQRKLSDQANTLVDLSKMQNVMYDLITELNDRSEDLEKQIGSLESKLEHLTASF 670
LRSVKMEQRKLSDQANTLVDLSKMQNVMYDLITELNDRSEDLEKQIGSLESKLEHLTASF
Sbjct: 306 LRSVKMEQRKLSDQANTLVDLSKMQNVMYDLITELNDRSEDLEKQIGSLESKLEHLTASF 365
Query: 671 NSLPLLIADTLRQQQQQLLSAIIEARGVSVAVGTTHTPISDSPIGVSSTSFPTPYTSSSS 730
NSLPLLIADTLRQQQQQLLSAIIEARGVSVAVGTTHTPISDSPIGVSSTSFPTPYTSSSS
Sbjct: 366 NSLPLLIADTLRQQQQQLLSAIIEARGVSVAVGTTHTPISDSPIGVSSTSFPTPYTSSSS 425
Query: 731 C 731
C
Sbjct: 426 C 426
>gi|25777645 small conductance calcium-activated potassium channel
protein 2 isoform a [Homo sapiens]
Length = 579
Score = 816 bits (2108), Expect = 0.0
Identities = 427/579 (73%), Positives = 476/579 (82%), Gaps = 25/579 (4%)
Query: 175 MSSCKYSGGVMKPLSRLSASRRNLIEAETEGQPLQ----------LFSPS---------- 214
MSSC+Y+GGVM+PLS LSASRRNL E ++E QPLQ SPS
Sbjct: 1 MSSCRYNGGVMRPLSNLSASRRNLHEMDSEAQPLQPPASVGGGGGASSPSAAAAAAAAVS 60
Query: 215 -NPPEIVISSREDNHAHQTLLHHPNATHNHQHAG----TTASSTTFPKANKRKNQNIGYK 269
+ PEIV+S E N+++ L+ + G + S++ K++K+KNQNIGYK
Sbjct: 61 SSAPEIVVSKPEHNNSNNLALYGTGGGGSTGGGGGGGGSGHGSSSGTKSSKKKNQNIGYK 120
Query: 270 LGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGLYSKDSMFSLALKCLISLSTII 329
LGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWG Y K S++SLALKCLISLSTII
Sbjct: 121 LGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGAYDKASLYSLALKCLISLSTII 180
Query: 330 LLGLIIAYHTREVQLFVIDNGADDWRIAMTYERILYISLEMLVCAIHPIPGEYKFFWTAR 389
LLGLII YH RE+QLF++DNGADDWRIAMTYERI +I LE+LVCAIHPIPG Y F WTAR
Sbjct: 181 LLGLIIVYHAREIQLFMVDNGADDWRIAMTYERIFFICLEILVCAIHPIPGNYTFTWTAR 240
Query: 390 LAFSYTPSRAEADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRF 449
LAFSY PS ADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRF
Sbjct: 241 LAFSYAPSTTTADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRF 300
Query: 450 VMKTLMTICPGTVLLVFSISLWIIAAWTVRVCERYHDQQDVTSNFLGAMWLISITFLSIG 509
VMKTLMTICPGTVLLVFSISLWIIAAWTVR CERYHDQQDVTSNFLGAMWLISITFLSIG
Sbjct: 301 VMKTLMTICPGTVLLVFSISLWIIAAWTVRACERYHDQQDVTSNFLGAMWLISITFLSIG 360
Query: 510 YGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRIK 569
YGDMVP+TYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKR+K
Sbjct: 361 YGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVK 420
Query: 570 NAAANVLRETWLIYKHTKLLKKIDHAKVRKHQRKFLQAIHQLRSVKMEQRKLSDQANTLV 629
NAAANVLRETWLIYK+TKL+KKIDHAKVRKHQRKFLQAIHQLRSVKMEQRKL+DQANTLV
Sbjct: 421 NAAANVLRETWLIYKNTKLVKKIDHAKVRKHQRKFLQAIHQLRSVKMEQRKLNDQANTLV 480
Query: 630 DLSKMQNVMYDLITELNDRSEDLEKQIGSLESKLEHLTASFNSLPLLIADTLRQQQQQLL 689
DL+K QN+MYD+I++LN+RSED EK+I +LE+KLE L S ++LP LI+ T+RQQQ+ +
Sbjct: 481 DLAKTQNIMYDMISDLNERSEDFEKRIVTLETKLETLIGSIHALPGLISQTIRQQQRDFI 540
Query: 690 SAIIEARGVSVAVGTTHTPISDSPIGVSSTSFPTPYTSS 728
A +E+ V + S SST+ PT SS
Sbjct: 541 EAQMESYDKHVTYNAERSRSSSRRRRSSSTAPPTSSESS 579
>gi|25777643 potassium intermediate/small conductance
calcium-activated channel, subfamily N, member 1 [Homo
sapiens]
Length = 543
Score = 698 bits (1802), Expect = 0.0
Identities = 343/424 (80%), Positives = 386/424 (91%), Gaps = 3/424 (0%)
Query: 262 KNQNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGLYSKDSMFSLALKC 321
K N+G++LGHRRALFEKRKRLSDYALIFGMFGIVVMV ETELSWG+Y+K+S++S ALKC
Sbjct: 85 KPSNVGHRLGHRRALFEKRKRLSDYALIFGMFGIVVMVTETELSWGVYTKESLYSFALKC 144
Query: 322 LISLSTIILLGLIIAYHTREVQLFVIDNGADDWRIAMTYERILYISLEMLVCAIHPIPGE 381
LISLST ILLGL++ YH RE+QLF++DNGADDWRIAMT ER+ ISLE+ VCAIHP+PG
Sbjct: 145 LISLSTAILLGLVVLYHAREIQLFMVDNGADDWRIAMTCERVFLISLELAVCAIHPVPGH 204
Query: 382 YKFFWTARLAFSYTPSRAEADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALN 441
Y+F WTARLAF+Y PS AEADVD++LSIPMFLRLYL+ RVMLLHSK+FTDASSRSIGALN
Sbjct: 205 YRFTWTARLAFTYAPSVAEADVDVLLSIPMFLRLYLLGRVMLLHSKIFTDASSRSIGALN 264
Query: 442 KINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRVCERYHDQQDVTSNFLGAMWLI 501
KI FNTRFVMKTLMTICPGTVLLVFSIS WIIAAWTVRVCERYHD+Q+VTSNFLGAMWLI
Sbjct: 265 KITFNTRFVMKTLMTICPGTVLLVFSISSWIIAAWTVRVCERYHDKQEVTSNFLGAMWLI 324
Query: 502 SITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMD 561
SITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMD
Sbjct: 325 SITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMD 384
Query: 562 TQLTKRIKNAAANVLRETWLIYKHTKLLKKIDHAKVRKHQRKFLQAIHQ---LRSVKMEQ 618
TQLTKR+KNAAANVLRETWLIYKHT+L+KK D A+VRKHQRKFLQAIHQ LRSVK+EQ
Sbjct: 385 TQLTKRVKNAAANVLRETWLIYKHTRLVKKPDQARVRKHQRKFLQAIHQAQKLRSVKIEQ 444
Query: 619 RKLSDQANTLVDLSKMQNVMYDLITELNDRSEDLEKQIGSLESKLEHLTASFNSLPLLIA 678
KL+DQANTL DL+K Q VMYDL++EL+ + E+LE ++ +LES+L+ L AS +LP LIA
Sbjct: 445 GKLNDQANTLTDLAKTQTVMYDLVSELHAQHEELEARLATLESRLDALGASLQALPGLIA 504
Query: 679 DTLR 682
+R
Sbjct: 505 QAIR 508
>gi|4504859 intermediate conductance calcium-activated potassium
channel protein 1 [Homo sapiens]
Length = 427
Score = 340 bits (873), Expect = 2e-93
Identities = 188/405 (46%), Positives = 256/405 (63%), Gaps = 16/405 (3%)
Query: 270 LGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGLYSKDSMFSLALKCLISLSTII 329
L R+ L E+ K L+ +AL+ GI +MV+ E+ W +++ +KC IS+ST +
Sbjct: 12 LRRRKRLLEQEKSLAGWALVLAGTGIGLMVLHAEMLWFGGCSWALYLFLVKCTISISTFL 71
Query: 330 LLGLIIAYHTREVQLFVIDNGADDWRIAMTYERILYISLEMLVCAIHPIP-------GEY 382
LL LI+A+H +EVQLF+ DNG DWR+A+T + I LE++VC +HP P +
Sbjct: 72 LLCLIVAFHAKEVQLFMTDNGLRDWRVALTGRQAAQIVLELVVCGLHPAPVRGPPCVQDL 131
Query: 383 KFFWTARLAFSYTPSRAEADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNK 442
T+ + + EA +LS+ M LRLYL+ R +LL S + +AS RSIGALN+
Sbjct: 132 GAPLTSPQPWPGFLGQGEA----LLSLAMLLRLYLVPRAVLLRSGVLLNASYRSIGALNQ 187
Query: 443 INFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRVCERYHDQQDVTSNFLGAMWLIS 502
+ F FV K M PG +LL ++ LW+ AW + V ER + T + +WLI
Sbjct: 188 VRFRHWFVAKLYMNTHPGRLLLGLTLGLWLTTAWVLSVAER--QAVNATGHLSDTLWLIP 245
Query: 503 ITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDT 562
ITFL+IGYGD+VP T GK VCL TG+MG CTAL+VAVVARKLE KAEKHVHNFMMD
Sbjct: 246 ITFLTIGYGDVVPGTMWGKIVCLCTGVMGVCCTALLVAVVARKLEFNKAEKHVHNFMMDI 305
Query: 563 QLTKRIKNAAANVLRETWLIYKHTKLLKKIDHAKVRKHQRKFLQAIHQLRSVKMEQRKLS 622
Q TK +K +AA VL+E W+ YKHT+ +K HA R+HQRK L AI+ R V+++ RKL
Sbjct: 306 QYTKEMKESAARVLQEAWMFYKHTR--RKESHA-ARRHQRKLLAAINAFRQVRLKHRKLR 362
Query: 623 DQANTLVDLSKMQNVMYDLITELNDRSEDLEKQIGSLESKLEHLT 667
+Q N++VD+SKM ++YDL L+ LEKQI +L KL+ LT
Sbjct: 363 EQVNSMVDISKMHMILYDLQQNLSSSHRALEKQIDTLAGKLDALT 407
>gi|25777647 small conductance calcium-activated potassium channel
protein 2 isoform b [Homo sapiens]
Length = 231
Score = 335 bits (859), Expect = 9e-92
Identities = 172/231 (74%), Positives = 196/231 (84%)
Query: 498 MWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHN 557
MWLISITFLSIGYGDMVP+TYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHN
Sbjct: 1 MWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHN 60
Query: 558 FMMDTQLTKRIKNAAANVLRETWLIYKHTKLLKKIDHAKVRKHQRKFLQAIHQLRSVKME 617
FMMDTQLTKR+KNAAANVLRETWLIYK+TKL+KKIDHAKVRKHQRKFLQAIHQLRSVKME
Sbjct: 61 FMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHAKVRKHQRKFLQAIHQLRSVKME 120
Query: 618 QRKLSDQANTLVDLSKMQNVMYDLITELNDRSEDLEKQIGSLESKLEHLTASFNSLPLLI 677
QRKL+DQANTLVDL+K QN+MYD+I++LN+RSED EK+I +LE+KLE L S ++LP LI
Sbjct: 121 QRKLNDQANTLVDLAKTQNIMYDMISDLNERSEDFEKRIVTLETKLETLIGSIHALPGLI 180
Query: 678 ADTLRQQQQQLLSAIIEARGVSVAVGTTHTPISDSPIGVSSTSFPTPYTSS 728
+ T+RQQQ+ + A +E+ V + S SST+ PT SS
Sbjct: 181 SQTIRQQQRDFIEAQMESYDKHVTYNAERSRSSSRRRRSSSTAPPTSSESS 231
>gi|33286444 mastermind-like 2 [Homo sapiens]
Length = 1156
Score = 65.1 bits (157), Expect = 2e-10
Identities = 42/74 (56%), Positives = 46/74 (62%), Gaps = 6/74 (8%)
Query: 29 EQQQQQQQQQQQQPPPPAPPAAPQQPLGPSL-----QPQPPQLQQQQQQQQQQQQQQPPH 83
+QQQQQQQQQQQQ + A QQ S+ Q Q Q QQQQQQQQQQQQQQ
Sbjct: 606 QQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQ 665
Query: 84 PLSQLAQ-LQSQPV 96
P SQ AQ L SQP+
Sbjct: 666 PSSQPAQSLPSQPL 679
Score = 61.2 bits (147), Expect = 3e-09
Identities = 51/144 (35%), Positives = 56/144 (38%), Gaps = 19/144 (13%)
Query: 29 EQQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQPQPPQ-----LQQQQQQQQQQQQQQPPH 83
+QQQQQQQQQQQQ QQ S Q Q Q QQQQQQQQQQQQQQ
Sbjct: 596 QQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQ 655
Query: 84 PLSQLAQLQSQPVHPGLLHSSPTAFRAPPSSNSTAILHPSSRQ---------GSQLNLND 134
Q Q Q P S R+P +L Q Q +
Sbjct: 656 QQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQVSQQQRQDQ 715
Query: 135 HLL-----GHSPSSTATSGPGGGS 153
H + G SPS S P GS
Sbjct: 716 HSVVGQNTGPSPSPNPCSNPNTGS 739
Score = 48.5 bits (114), Expect = 2e-05
Identities = 41/112 (36%), Positives = 57/112 (50%), Gaps = 6/112 (5%)
Query: 29 EQQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQQQQQQQQPPHPLS-Q 87
+QQQQQQQQQQQQ P + P Q L PS L QQ+ QQ Q QP + Q
Sbjct: 648 QQQQQQQQQQQQQQQQQQPSSQPAQSL-PSQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQ 706
Query: 88 LAQLQSQPVHPGL-LHSSPTAFRAPPSSNSTAILHPSSRQGSQLNLNDHLLG 138
++Q Q Q H + ++ P+ P S+ +T + +S+Q LN L+G
Sbjct: 707 VSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQQSL---LNQQLMG 755
Score = 48.1 bits (113), Expect = 3e-05
Identities = 35/70 (50%), Positives = 35/70 (50%), Gaps = 15/70 (21%)
Query: 30 QQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQ-----QQQQQQQPPHP 84
QQQQQQQQQQQQ QQ Q Q Q QQQQQQQ QQQQQQQ
Sbjct: 588 QQQQQQQQQQQQ----------QQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSIS 637
Query: 85 LSQLAQLQSQ 94
Q Q Q Q
Sbjct: 638 AQQQQQQQQQ 647
Score = 43.1 bits (100), Expect = 0.001
Identities = 27/57 (47%), Positives = 28/57 (49%)
Query: 37 QQQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQQQQQQQQPPHPLSQLAQLQS 93
Q QQ P P L + Q Q Q QQQQQQQQQQQQQQ Q Q QS
Sbjct: 566 QANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQS 622
Score = 41.2 bits (95), Expect = 0.003
Identities = 25/59 (42%), Positives = 28/59 (47%)
Query: 38 QQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQQQQQQQQPPHPLSQLAQLQSQPV 96
Q Q P P+ + L Q Q Q QQQQQQQQQQQQQQ Q Q Q +
Sbjct: 566 QANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSI 624
Score = 32.3 bits (72), Expect = 1.6
Identities = 36/137 (26%), Positives = 46/137 (33%), Gaps = 14/137 (10%)
Query: 19 PKCPCPSSGDEQQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQQQQQ- 77
P+ PS+G P P P + Q G P Q+ QQ +Q
Sbjct: 380 PQLRPPSAGPAFSMANSALSTSSPIPSVPQSQAQPQTGSGASRALPSWQEVSHAQQLKQI 439
Query: 78 -QQQPPHPLSQLAQLQSQPVHPGLLHSSPTAFRAPPSSNSTAILHPSSRQGSQLNLNDHL 136
+ H Q Q Q QP + L SS A +P I PS Q +
Sbjct: 440 AANRQQHARMQQHQQQHQPTNWSALPSS--AGPSPGPFGQEKIPSPSFGQQT-------- 489
Query: 137 LGHSPSSTATSGPGGGS 153
SP S+ G GGS
Sbjct: 490 --FSPQSSPMPGVAGGS 504
Score = 32.0 bits (71), Expect = 2.1
Identities = 24/87 (27%), Positives = 30/87 (34%), Gaps = 17/87 (19%)
Query: 42 PPPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQQQQQ-----------QQQPPHPL----- 85
PPPPA P A Q + P PP QQ +QQPP
Sbjct: 106 PPPPAAPPAASQAAATAAPPPPPDYHHHHQQHLLNSSNNGGSGGINGEQQPPASTPGDQR 165
Query: 86 -SQLAQLQSQPVHPGLLHSSPTAFRAP 111
S L LQ +++ SP + P
Sbjct: 166 NSALIALQGSLKRKQVVNLSPANSKRP 192
>gi|114431236 zinc finger protein 462 [Homo sapiens]
Length = 2506
Score = 63.2 bits (152), Expect = 8e-10
Identities = 34/64 (53%), Positives = 36/64 (56%), Gaps = 2/64 (3%)
Query: 35 QQQQQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQQQQQQQQPPHPLSQLAQLQSQ 94
QQQQ QPPPP PP P QP P QPQPPQLQ Q Q Q Q PP Q Q+
Sbjct: 538 QQQQPPQPPPPPPPPPPSQPQ-PLQQPQPPQLQPPHQVPPQPQTQPPPTQQPQ-PPTQAA 595
Query: 95 PVHP 98
P+HP
Sbjct: 596 PLHP 599
Score = 39.3 bits (90), Expect = 0.013
Identities = 38/118 (32%), Positives = 42/118 (35%), Gaps = 25/118 (21%)
Query: 19 PKCPCPSSGDEQQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQQQQQQ 78
P P P Q QQ Q Q QPP PP QP P+ QPQPP Q
Sbjct: 547 PPPPPPPPSQPQPLQQPQPPQLQPPHQVPPQPQTQP-PPTQQPQPP------------TQ 593
Query: 79 QQPPHPLS------QLAQLQSQPVHPGLLHS---SPTAFRAPPSS---NSTAILHPSS 124
P HP L+ VH HS + F PSS + HPSS
Sbjct: 594 AAPLHPYKCTMCNYSTTTLKGLRVHQQHKHSFCDNLPKFEGQPSSLPLENETDSHPSS 651
>gi|110347429 mediator complex subunit 12 [Homo sapiens]
Length = 2177
Score = 62.0 bits (149), Expect = 2e-09
Identities = 38/70 (54%), Positives = 40/70 (57%), Gaps = 2/70 (2%)
Query: 29 EQQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQQQQQQQQPPHPLSQL 88
+QQQQQQQQQQQQ QQ L Q Q Q QQQQQQQQQQQQQQ H Q
Sbjct: 2062 QQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQH--QQQ 2119
Query: 89 AQLQSQPVHP 98
Q Q+ P P
Sbjct: 2120 QQQQAAPPQP 2129
Score = 58.2 bits (139), Expect = 3e-08
Identities = 35/70 (50%), Positives = 37/70 (52%)
Query: 29 EQQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQQQQQQQQPPHPLSQL 88
+QQQQQQQQQQQQ QQ L+ Q Q QQQQQQQQQQQQQQ
Sbjct: 2058 QQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQ 2117
Query: 89 AQLQSQPVHP 98
Q Q Q P
Sbjct: 2118 QQQQQQAAPP 2127
Score = 57.0 bits (136), Expect = 6e-08
Identities = 34/66 (51%), Positives = 36/66 (54%)
Query: 29 EQQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQQQQQQQQPPHPLSQL 88
EQQQQQQQQQQQQ QQ Q Q Q+ +QQQQQQQQQQQQ Q
Sbjct: 2050 EQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQ 2109
Query: 89 AQLQSQ 94
Q Q Q
Sbjct: 2110 QQQQQQ 2115
Score = 52.8 bits (125), Expect = 1e-06
Identities = 36/67 (53%), Positives = 37/67 (55%), Gaps = 21/67 (31%)
Query: 29 EQQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQQQQQQQQPPHPLSQL 88
+QQQQQQQQQQQQ QQ Q Q Q QQQQ QQQQQQQ PP P
Sbjct: 2090 QQQQQQQQQQQQQ----------QQ------QQQQQQQQQQQHQQQQQQQAAPPQP---- 2129
Query: 89 AQLQSQP 95
Q QSQP
Sbjct: 2130 -QPQSQP 2135
Score = 51.2 bits (121), Expect = 3e-06
Identities = 34/71 (47%), Positives = 37/71 (52%), Gaps = 4/71 (5%)
Query: 29 EQQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQPQ-PPQLQQQQQQQQQQQQQQPP---HP 84
+QQQQQQQQQQQQ QQ P QPQ PQ Q+Q QQ QQQQQ
Sbjct: 2099 QQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQL 2158
Query: 85 LSQLAQLQSQP 95
QL+ Q QP
Sbjct: 2159 QQQLSNTQPQP 2169
Score = 49.7 bits (117), Expect = 1e-05
Identities = 31/67 (46%), Positives = 36/67 (53%), Gaps = 1/67 (1%)
Query: 29 EQQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQPQP-PQLQQQQQQQQQQQQQQPPHPLSQ 87
+QQQQQQQQQQQQ QQ + PQP PQ Q Q Q+Q QQ QQ +
Sbjct: 2095 QQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAAL 2154
Query: 88 LAQLQSQ 94
+ QLQ Q
Sbjct: 2155 VRQLQQQ 2161
Score = 41.6 bits (96), Expect = 0.003
Identities = 31/70 (44%), Positives = 32/70 (45%), Gaps = 15/70 (21%)
Query: 30 QQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQ-----QQQQQQQPPHP 84
+QQQQQQQQQQQ QQ Q Q Q QQQQQQ Q Q Q QP
Sbjct: 2089 RQQQQQQQQQQQ----------QQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQ 2138
Query: 85 LSQLAQLQSQ 94
L Q Q Q
Sbjct: 2139 RQGLQQTQQQ 2148
Score = 38.1 bits (87), Expect = 0.029
Identities = 26/81 (32%), Positives = 34/81 (41%), Gaps = 6/81 (7%)
Query: 20 KCPCPSSGDEQQQQQQQQQQQQPP------PPAPPAAPQQPLGPSLQPQPPQLQQQQQQQ 73
+ P G Q+ Q QQ P P + ++ P+ Q QQQQQQQ
Sbjct: 2002 QAPTYGHGLTSTQRFSHQTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQ 2061
Query: 74 QQQQQQQPPHPLSQLAQLQSQ 94
QQQQQQQ Q ++ Q
Sbjct: 2062 QQQQQQQQQQQQQQQYHIRQQ 2082
Score = 38.1 bits (87), Expect = 0.029
Identities = 21/38 (55%), Positives = 21/38 (55%)
Query: 57 PSLQPQPPQLQQQQQQQQQQQQQQPPHPLSQLAQLQSQ 94
P Q Q Q QQQQQQQQQQQQQQ Q Q Q
Sbjct: 2049 PEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQ 2086
Score = 36.2 bits (82), Expect = 0.11
Identities = 22/65 (33%), Positives = 26/65 (40%)
Query: 33 QQQQQQQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQQQQQQQQPPHPLSQLAQLQ 92
Q+ Q Q P P G + + +QQQQQQQQQQQ Q Q Q
Sbjct: 2014 QRFSHQTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQ 2073
Query: 93 SQPVH 97
Q H
Sbjct: 2074 QQQYH 2078
Score = 35.8 bits (81), Expect = 0.15
Identities = 21/40 (52%), Positives = 23/40 (57%), Gaps = 2/40 (5%)
Query: 59 LQPQPPQLQQQQQQQQQQQQQQPPHPLSQ--LAQLQSQPV 96
L Q Q QQQQQQQQQQQQQQ Q + Q Q Q +
Sbjct: 2048 LPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQI 2087
Score = 30.4 bits (67), Expect = 6.1
Identities = 39/165 (23%), Positives = 61/165 (36%), Gaps = 30/165 (18%)
Query: 88 LAQLQSQPVHPGLLHSSPTAFRA-PPSSNSTAILH---PSSRQGS----QLNLNDHLLGH 139
+ +L ++P +PG+L ++ T PSS T++ P+ QG QL + +LG
Sbjct: 1865 MQKLPTRPTYPGVLPTTMTGVMGLEPSSYKTSVYRQQQPAVPQGQRLRQQLQQSQGMLGQ 1924
Query: 140 SPSSTATSGPGGGSRHRQA-SPLVHRRDSNPFTEIAMSSCKYSGGVMKPLSRLSASRRNL 198
S T G + Q +P V + + + G M P S S
Sbjct: 1925 SSVHQMTPSSSYGLQTSQGYTPYV--------SHVGLQQHTGPAGTMVPPSYSS------ 1970
Query: 199 IEAETEGQPLQLFSPSNPPEIVISSREDNHAHQTLLHHPNATHNH 243
QP Q PS P +V +R +H T+ H
Sbjct: 1971 -------QPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGH 2008
>gi|17017963 forkhead box P2 isoform I [Homo sapiens]
Length = 715
Score = 61.6 bits (148), Expect = 2e-09
Identities = 63/187 (33%), Positives = 77/187 (41%), Gaps = 31/187 (16%)
Query: 29 EQQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQQQQQQQQPPHPLSQL 88
+QQQQQQQQQQQQ QQ P Q + Q QQQQQQQ QQ L Q+
Sbjct: 165 QQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQM 224
Query: 89 AQLQSQP-----VHPGLLHSSPTAFRAPPSSNSTAILHPSSRQGSQL--------NLNDH 135
QLQ Q GL+ P P S A L P+ Q QL ++ D+
Sbjct: 225 QQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQ--QLWKEVTGVHSMEDN 282
Query: 136 LLGH--------SPSSTATSGPGGGSR--------HRQASPLVHRRDSNPFTEIAMSSCK 179
+ H + SST +S S + Q+S L RRDS+ E S
Sbjct: 283 GIKHGGLDLTTNNSSSTTSSNTSKASPPITHHSIVNGQSSVLSARRDSSSHEETGASHTL 342
Query: 180 YSGGVMK 186
Y GV K
Sbjct: 343 YGHGVCK 349
Score = 59.7 bits (143), Expect = 9e-09
Identities = 61/209 (29%), Positives = 80/209 (38%), Gaps = 32/209 (15%)
Query: 29 EQQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQQQQQQQQPPHPLSQL 88
+QQQQQQQQQQQQ QQ Q Q Q QQQQQQQQQQQQQQ HP Q
Sbjct: 152 QQQQQQQQQQQQQ----------QQ----QQQQQQQQQQQQQQQQQQQQQQQQQHPGKQA 197
Query: 89 AQLQSQPVHPGLLHSSPTAFRAPPSSNSTAILHPSSRQGSQLNLNDHLLGHSPSSTATSG 148
+ Q Q L + F+ Q QL HLL +
Sbjct: 198 KEQQQQQQQQQQLAAQQLVFQ------------QQLLQMQQLQQQQHLLSLQRQGLISIP 245
Query: 149 PGGGSRHRQASP---LVHRRDSNPFTEIAMSSCKYSGGVMK---PLSRLSASRRNLIEAE 202
PG + Q+ P L + E+ G+ L+ ++S
Sbjct: 246 PGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIKHGGLDLTTNNSSSTTSSNTS 305
Query: 203 TEGQPLQLFSPSNPPEIVISSREDNHAHQ 231
P+ S N V+S+R D+ +H+
Sbjct: 306 KASPPITHHSIVNGQSSVLSARRDSSSHE 334
>gi|22538413 forkhead box P2 isoform III [Homo sapiens]
Length = 623
Score = 61.6 bits (148), Expect = 2e-09
Identities = 63/187 (33%), Positives = 77/187 (41%), Gaps = 31/187 (16%)
Query: 29 EQQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQQQQQQQQPPHPLSQL 88
+QQQQQQQQQQQQ QQ P Q + Q QQQQQQQ QQ L Q+
Sbjct: 73 QQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQM 132
Query: 89 AQLQSQP-----VHPGLLHSSPTAFRAPPSSNSTAILHPSSRQGSQL--------NLNDH 135
QLQ Q GL+ P P S A L P+ Q QL ++ D+
Sbjct: 133 QQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQ--QLWKEVTGVHSMEDN 190
Query: 136 LLGH--------SPSSTATSGPGGGSR--------HRQASPLVHRRDSNPFTEIAMSSCK 179
+ H + SST +S S + Q+S L RRDS+ E S
Sbjct: 191 GIKHGGLDLTTNNSSSTTSSNTSKASPPITHHSIVNGQSSVLSARRDSSSHEETGASHTL 250
Query: 180 YSGGVMK 186
Y GV K
Sbjct: 251 YGHGVCK 257
Score = 59.7 bits (143), Expect = 9e-09
Identities = 61/209 (29%), Positives = 80/209 (38%), Gaps = 32/209 (15%)
Query: 29 EQQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQQQQQQQQPPHPLSQL 88
+QQQQQQQQQQQQ QQ Q Q Q QQQQQQQQQQQQQQ HP Q
Sbjct: 60 QQQQQQQQQQQQQ----------QQ----QQQQQQQQQQQQQQQQQQQQQQQQQHPGKQA 105
Query: 89 AQLQSQPVHPGLLHSSPTAFRAPPSSNSTAILHPSSRQGSQLNLNDHLLGHSPSSTATSG 148
+ Q Q L + F+ Q QL HLL +
Sbjct: 106 KEQQQQQQQQQQLAAQQLVFQ------------QQLLQMQQLQQQQHLLSLQRQGLISIP 153
Query: 149 PGGGSRHRQASP---LVHRRDSNPFTEIAMSSCKYSGGVMK---PLSRLSASRRNLIEAE 202
PG + Q+ P L + E+ G+ L+ ++S
Sbjct: 154 PGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIKHGGLDLTTNNSSSTTSSNTS 213
Query: 203 TEGQPLQLFSPSNPPEIVISSREDNHAHQ 231
P+ S N V+S+R D+ +H+
Sbjct: 214 KASPPITHHSIVNGQSSVLSARRDSSSHE 242
>gi|149999352 forkhead box P2 isoform II [Homo sapiens]
Length = 740
Score = 61.6 bits (148), Expect = 2e-09
Identities = 63/187 (33%), Positives = 77/187 (41%), Gaps = 31/187 (16%)
Query: 29 EQQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQQQQQQQQPPHPLSQL 88
+QQQQQQQQQQQQ QQ P Q + Q QQQQQQQ QQ L Q+
Sbjct: 190 QQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQM 249
Query: 89 AQLQSQP-----VHPGLLHSSPTAFRAPPSSNSTAILHPSSRQGSQL--------NLNDH 135
QLQ Q GL+ P P S A L P+ Q QL ++ D+
Sbjct: 250 QQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQ--QLWKEVTGVHSMEDN 307
Query: 136 LLGH--------SPSSTATSGPGGGSR--------HRQASPLVHRRDSNPFTEIAMSSCK 179
+ H + SST +S S + Q+S L RRDS+ E S
Sbjct: 308 GIKHGGLDLTTNNSSSTTSSNTSKASPPITHHSIVNGQSSVLSARRDSSSHEETGASHTL 367
Query: 180 YSGGVMK 186
Y GV K
Sbjct: 368 YGHGVCK 374
Score = 59.7 bits (143), Expect = 9e-09
Identities = 61/209 (29%), Positives = 80/209 (38%), Gaps = 32/209 (15%)
Query: 29 EQQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQQQQQQQQPPHPLSQL 88
+QQQQQQQQQQQQ QQ Q Q Q QQQQQQQQQQQQQQ HP Q
Sbjct: 177 QQQQQQQQQQQQQ----------QQ----QQQQQQQQQQQQQQQQQQQQQQQQQHPGKQA 222
Query: 89 AQLQSQPVHPGLLHSSPTAFRAPPSSNSTAILHPSSRQGSQLNLNDHLLGHSPSSTATSG 148
+ Q Q L + F+ Q QL HLL +
Sbjct: 223 KEQQQQQQQQQQLAAQQLVFQ------------QQLLQMQQLQQQQHLLSLQRQGLISIP 270
Query: 149 PGGGSRHRQASP---LVHRRDSNPFTEIAMSSCKYSGGVMK---PLSRLSASRRNLIEAE 202
PG + Q+ P L + E+ G+ L+ ++S
Sbjct: 271 PGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIKHGGLDLTTNNSSSTTSSNTS 330
Query: 203 TEGQPLQLFSPSNPPEIVISSREDNHAHQ 231
P+ S N V+S+R D+ +H+
Sbjct: 331 KASPPITHHSIVNGQSSVLSARRDSSSHE 359
>gi|157743257 POU domain, class 6, transcription factor 2 [Homo
sapiens]
Length = 691
Score = 61.6 bits (148), Expect = 2e-09
Identities = 42/101 (41%), Positives = 46/101 (45%), Gaps = 2/101 (1%)
Query: 31 QQQQQQQQQQQPPPPAPPAAPQ-QPLGPSLQPQPPQLQQQQQQQQQQQQQQPPHPLSQLA 89
Q QQQQQQQQQ PPP+ PQ P PS Q P LQ QQ QQPP P SQL
Sbjct: 185 QLQQQQQQQQQQPPPSTNQHPQPAPQAPSQSQQQP-LQPTPPQQPPPASQQPPAPTSQLQ 243
Query: 90 QLQSQPVHPGLLHSSPTAFRAPPSSNSTAILHPSSRQGSQL 130
Q H HS +P +S+ PS G L
Sbjct: 244 QAPQPQQHQPHSHSQNQNQPSPTQQSSSPPQKPSQSPGHGL 284
Score = 56.6 bits (135), Expect = 8e-08
Identities = 45/109 (41%), Positives = 50/109 (45%), Gaps = 29/109 (26%)
Query: 30 QQQQQQQQQQQQPPP-------PAPPA---APQQPLGPSLQPQPP-----------QLQQ 68
Q QQQQQQQQQQPPP PAP A + QQPL P+ QPP QLQQ
Sbjct: 185 QLQQQQQQQQQQPPPSTNQHPQPAPQAPSQSQQQPLQPTPPQQPPPASQQPPAPTSQLQQ 244
Query: 69 QQQQQQQQ-----QQQQPPHPLSQLAQLQSQPVH-PGLLHSSPTAFRAP 111
Q QQ Q Q Q P P Q + +P PG H P+ P
Sbjct: 245 APQPQQHQPHSHSQNQNQPSPTQQSSSPPQKPSQSPG--HGLPSPLTPP 291
Score = 53.1 bits (126), Expect = 9e-07
Identities = 41/115 (35%), Positives = 54/115 (46%), Gaps = 11/115 (9%)
Query: 58 SLQPQPPQLQQQQQQQQQQQQQQPPHPLSQ--------LAQLQSQPVHPGLLHSSPTAFR 109
SL Q QLQ Q QQQQQQQQQQPP +Q +Q Q QP+ P P A +
Sbjct: 174 SLNSQLQQLQLQLQQQQQQQQQQPPPSTNQHPQPAPQAPSQSQQQPLQPTPPQQPPPASQ 233
Query: 110 APPSSNSTAILHPSSRQGSQLNLNDHLLGHSPSSTATSGPGGGSR---HRQASPL 161
PP+ S P +Q + + + SP+ ++S P S+ H SPL
Sbjct: 234 QPPAPTSQLQQAPQPQQHQPHSHSQNQNQPSPTQQSSSPPQKPSQSPGHGLPSPL 288
Score = 39.3 bits (90), Expect = 0.013
Identities = 44/160 (27%), Positives = 58/160 (36%), Gaps = 28/160 (17%)
Query: 19 PKCPCPSSGDEQQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQQQ--- 75
P PS +Q Q QQ P PP AP L + QPQ Q Q Q Q
Sbjct: 207 PAPQAPSQSQQQPLQPTPPQQPPPASQQPP-APTSQLQQAPQPQQHQPHSHSQNQNQPSP 265
Query: 76 -QQQQQPPHPLSQL----AQLQSQPVHPGLLHSSPTAFRAPPSSNSTAILHPSSRQGSQL 130
QQ PP SQ P +P L ++P A +A ++ + + + S G+ L
Sbjct: 266 TQQSSSPPQKPSQSPGHGLPSPLTPPNPLQLVNNPLASQAAAAAAAMSSIASSQAFGNAL 325
Query: 131 ------------NLNDHLLG-------HSPSSTATSGPGG 151
N ++G PSS A SG G
Sbjct: 326 SSLQGVTGQLVTNAQGQIIGTIPLMPNPGPSSQAASGTQG 365
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 59.7 bits (143), Expect = 9e-09
Identities = 39/106 (36%), Positives = 44/106 (41%), Gaps = 6/106 (5%)
Query: 15 LDEDPKCPCPSSGDEQQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQP---QPPQLQQQQQ 71
+ P P P QQQ QQQ PPPP P PQQ P +P QP Q Q
Sbjct: 950 VQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQ 1009
Query: 72 QQQQQQQQQPPHPLSQLAQLQSQPVHPGLL---HSSPTAFRAPPSS 114
Q Q QQPPHP QP P + H SP ++ P S
Sbjct: 1010 QPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYS 1055
Score = 58.5 bits (140), Expect = 2e-08
Identities = 61/216 (28%), Positives = 77/216 (35%), Gaps = 15/216 (6%)
Query: 16 DEDPKCPCPSSGDEQQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQQQ 75
DE+P P P + + Q QQ Q+ QPP P P+ Q P P PP QQQ QQQ
Sbjct: 915 DEEPPAP-PLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQ 973
Query: 76 QQQQQPPHPLSQLAQLQSQPVHPGLLHSSPTAFRAPPSSNSTAILHPSSRQGSQLNLNDH 135
PP P Q P P +H P F ST I P QG Q
Sbjct: 974 PPPPPPPQPQPPPQQQHQPPPRP--VHLQPMQF-------STHIQQPPPPQGQQPPHPPP 1024
Query: 136 LLGHSPSSTATSGPGGGSRHRQASPLVHRRD--SNPFTEIAMSSCKYSGGVMKPLSRLSA 193
G P + P +H SP H+ D S A S M L+
Sbjct: 1025 --GQQPPPPQPAKPQQVIQHHH-SPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTH 1081
Query: 194 SRRNLIEAETEGQPLQLFSPSNPPEIVISSREDNHA 229
+ + Q L+ S P +V+ E H+
Sbjct: 1082 QSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHS 1117
Score = 45.4 bits (106), Expect = 2e-04
Identities = 33/84 (39%), Positives = 38/84 (45%), Gaps = 13/84 (15%)
Query: 27 GDEQQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQQQQQQQQPPHPLS 86
G EQ++ QQ PAP PQQP P QP PP QQQQQ PP P
Sbjct: 732 GREQKKHHHHHHQQMQQAPAP--VPQQPPPPPQQPPPP------PPPQQQQQPPPPPPPP 783
Query: 87 QLAQLQSQPVHPGLLHSSPTAFRA 110
+ Q Q+ P + SSP F A
Sbjct: 784 SMPQ-QAAPA----MKSSPPPFIA 802
Score = 45.4 bits (106), Expect = 2e-04
Identities = 32/108 (29%), Positives = 40/108 (37%), Gaps = 6/108 (5%)
Query: 19 PKCPCPSSGDEQQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQQQQQQ 78
P+ P P QQQQQ PPPP PP+ PQQ PP + Q + Q
Sbjct: 754 PQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLP 813
Query: 79 QQPPHPLSQLAQ----LQSQPVHPGLLHSSPTAFRAPPSSNSTAILHP 122
P+ Q L + P L P PP N A++ P
Sbjct: 814 GSVFDPIGHFTQPILHLPQPELPPHL--PQPPEHSTPPHLNQHAVVSP 859
Score = 42.4 bits (98), Expect = 0.002
Identities = 41/148 (27%), Positives = 56/148 (37%), Gaps = 11/148 (7%)
Query: 29 EQQQQQQQQQQQQPPPPA----PPAAPQQPLGPSLQPQPPQLQQQQQQQQQQQQQQPPHP 84
+Q QQ QQPPPP PP PQQ P P PP + QQ + PP
Sbjct: 744 QQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSM--PQQAAPAMKSSPPPFI 801
Query: 85 LSQLAQLQSQPVHPGLLHSSPTAFRAPPSSNSTAILHPSSRQGSQLNLNDHLLGH---SP 141
+Q+ L +P PG + F P L P Q + + HL H SP
Sbjct: 802 ATQVPVL--EPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSP 859
Query: 142 SSTATSGPGGGSRHRQASPLVHRRDSNP 169
+ + P SR + + + + P
Sbjct: 860 PALHNALPQQPSRPSNRAAALPPKPARP 887
Score = 42.0 bits (97), Expect = 0.002
Identities = 21/53 (39%), Positives = 34/53 (64%)
Query: 28 DEQQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQQQQQQQQ 80
++QQQQ+Q+QQQQQ A AA P S QPQ QQ++ ++++Q+++
Sbjct: 1284 EQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQQRELARKREQERR 1336
Score = 38.9 bits (89), Expect = 0.017
Identities = 29/90 (32%), Positives = 35/90 (38%), Gaps = 20/90 (22%)
Query: 29 EQQQQQQQQQQQQPPPPA-PPAAPQQPLGPSLQPQPPQLQ-------------------Q 68
+Q + + PP PA PPA L PQPP Q Q
Sbjct: 868 QQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQ 927
Query: 69 QQQQQQQQQQQQPPHPLSQLAQLQSQPVHP 98
Q QQ Q+ QPP PL ++QSQP P
Sbjct: 928 MQLYLQQLQKVQPPTPLLPSVKVQSQPPPP 957
Score = 32.7 bits (73), Expect = 1.2
Identities = 16/32 (50%), Positives = 21/32 (65%)
Query: 67 QQQQQQQQQQQQQQPPHPLSQLAQLQSQPVHP 98
QQQQ+Q+QQQQQQQ ++ A Q+Q P
Sbjct: 1286 QQQQRQEQQQQQQQQAAAVAAAATPQAQSSQP 1317
Score = 31.6 bits (70), Expect = 2.7
Identities = 17/50 (34%), Positives = 29/50 (58%), Gaps = 2/50 (4%)
Query: 29 EQQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQQQQQQ 78
EQQQQQQQQ P A QP S+ Q +L ++++Q++++++
Sbjct: 1292 EQQQQQQQQAAAVAAAATPQAQSSQP--QSMLDQQRELARKREQERRRRE 1339
Score = 31.2 bits (69), Expect = 3.6
Identities = 24/84 (28%), Positives = 32/84 (38%), Gaps = 3/84 (3%)
Query: 24 PSSGDEQQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQQQQQQQQPPH 83
P++ Q Q Q PPP P + P L Q P + Q Q PP
Sbjct: 197 PNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQ 256
Query: 84 PLSQLAQLQSQPV--HPGLLHSSP 105
P A QPV HP ++ ++P
Sbjct: 257 PQPPPAP-APQPVQSHPPIIAATP 279
Score = 30.4 bits (67), Expect = 6.1
Identities = 16/32 (50%), Positives = 19/32 (59%)
Query: 62 QPPQLQQQQQQQQQQQQQQPPHPLSQLAQLQS 93
Q Q QQ+Q+QQQQQQQQ + Q QS
Sbjct: 1283 QEQQQQQRQEQQQQQQQQAAAVAAAATPQAQS 1314
>gi|27886520 nuclear factor of activated T-cells 5 isoform a [Homo
sapiens]
Length = 1455
Score = 59.3 bits (142), Expect = 1e-08
Identities = 75/257 (29%), Positives = 96/257 (37%), Gaps = 65/257 (25%)
Query: 24 PSSGDEQQQQQQQQQQQQPPPP---------APPAAPQQP-----LGPSLQPQPPQLQQQ 69
PS +QQQQQQQQQQQQ A A+P+QP P+ P Q QQ
Sbjct: 1170 PSQEQQQQQQQQQQQQQQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNPMANQEQQN 1229
Query: 70 QQQQQQQQQQQPPHPLSQLAQLQSQPV-----HPG----------LLHSSP--TAFRAPP 112
Q QQ P + Q Q QSQ +PG L HSSP + P
Sbjct: 1230 QSIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQNPGPTQSESSQTPLFHSSPQIQLVQGSP 1289
Query: 113 SSNS---TAILHPSSRQGSQLNLNDHLLGHSPSST----------ATSGP---------- 149
SS T L P+S Q ++N + SP + ATS P
Sbjct: 1290 SSQEQQVTLFLSPASMSALQTSINQQDMQQSPLYSPQNNMPGIQGATSSPQPQATLFHNT 1349
Query: 150 -GGGSRHRQASPLVHRRDSNPFTEIAMSSCKY---SGGVMKPLSRLSASRRNLIEAETEG 205
GG Q SP ++ S F ++C SG P ++ S+ + + EG
Sbjct: 1350 AGGTMNQLQNSPGSSQQTSGMFLFGIQNNCSQLLTSGPATLPDQLMAISQPG--QPQNEG 1407
Query: 206 QP-----LQLFSPSNPP 217
QP L P N P
Sbjct: 1408 QPPVTTLLSQQMPENSP 1424
Score = 50.4 bits (119), Expect = 6e-06
Identities = 58/248 (23%), Positives = 94/248 (37%), Gaps = 30/248 (12%)
Query: 30 QQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQ-----------------PQPPQLQQQQQQ 72
Q+Q Q QQ P A + P P+ S Q P Q QQQQQQ
Sbjct: 1122 QEQAQPPQQGLFQPQVALGSLPPNPMPQSQQGTMFQSQHSIVAMQSNSPSQEQQQQQQQQ 1181
Query: 73 QQQQQQQQP------PHPLSQLAQLQSQPVHPGLLHSSPTAFRAPPSSNSTAILHPSSRQ 126
QQQQQQQQ + ++ +A + P P ++ + A + +I H S
Sbjct: 1182 QQQQQQQQQSILFSNQNTMATMASPKQPP--PNMIFNPNQNPMANQEQQNQSIFHQQSNM 1239
Query: 127 GSQLNLNDHLLGHSPSSTATS--GPGGGSRHRQASPLVHRRDSNPFTEIAMSSCKYSGGV 184
+ +N + ST +S PG +PL H + + SS + +
Sbjct: 1240 -APMNQEQQPMQFQSQSTVSSLQNPGPTQSESSQTPLFHSSPQIQLVQGSPSSQEQQVTL 1298
Query: 185 MKPLSRLSASRRNLIEAETEGQPLQLFSPSNPPEIVISSREDNHAHQTLLHHPNATHNHQ 244
+ +SA + ++ + + + P L+SP N + + TL H+ +Q
Sbjct: 1299 FLSPASMSALQTSINQQDMQQSP--LYSPQNNMPGIQGATSSPQPQATLFHNTAGGTMNQ 1356
Query: 245 HAGTTASS 252
+ SS
Sbjct: 1357 LQNSPGSS 1364
Score = 38.1 bits (87), Expect = 0.029
Identities = 57/251 (22%), Positives = 87/251 (34%), Gaps = 24/251 (9%)
Query: 24 PSSGDEQQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQ---------QQQQQ 74
P S + QQQQQQQQQ + AA + S+ Q+Q + QQ
Sbjct: 794 PQSENTLSNQQQQQQQQQQVMES-SAAMVMEMQQSICQAAAQIQSELFPSTASANGNLQQ 852
Query: 75 QQQQQQPPHPLSQLAQLQSQPVHPGLLHSSP---------TAFRAPPSSNSTAILHPSSR 125
QQ H +S L+ + + L S P T + + +T SS
Sbjct: 853 SPVYQQTSHMMSALSTNEDMQMQCELFSSPPAVSGNETSTTTTQQVATPGTTMFQTSSSG 912
Query: 126 QGSQLNLNDHLLGHSPSSTATSGPGGGSRHRQASPLVHRRDSNPFTEIAMSSCKYSGGVM 185
G + + +S T G Q + L S + + + + +G
Sbjct: 913 DGEETGTQAKQIQNSVFQTMVQMQHSGDNQPQVN-LFSSTKSMMSVQNSGTQQQGNGLFQ 971
Query: 186 KPLSRLSASRRNLIEAETEGQPLQLFSPSNPPEIVISSREDNHAHQTLLHHPNATHNHQH 245
+ +S N ++ + Q QLF P NP I + +L H PN H
Sbjct: 972 QGNEMMSLQSGNFLQQSSHSQ-AQLFHPQNP--IADAQNLSQETQGSLFHSPNPI-VHSQ 1027
Query: 246 AGTTASSTTFP 256
TT+S P
Sbjct: 1028 TSTTSSEQMQP 1038
Score = 31.2 bits (69), Expect = 3.6
Identities = 36/146 (24%), Positives = 51/146 (34%), Gaps = 39/146 (26%)
Query: 10 SGVGDLDEDPKCPCPSSGDEQQQQQ------------QQQQQQQPPP-PAPPAAPQQPLG 56
+G G PS ++QQQ Q Q Q QP PA A+ Q P
Sbjct: 566 AGNGSFSSPSSSHLPSENEKQQQIQPKAYNPETLTTIQTQDISQPGTFPAVSASSQLPNS 625
Query: 57 PSLQPQPPQLQQQQQQQQQ----------------QQQQQPPHPLSQLAQLQSQPVHPGL 100
+L Q Q Q ++ Q ++ QQQ PL + AQ Q + +
Sbjct: 626 DALLQQATQFQTRETQSREILQSDGTVVNLSQLTEASQQQQQSPLQEQAQTLQQQISSNI 685
Query: 101 LHSSPTAFRAPPSSNSTAILHPSSRQ 126
PS NS + L + +Q
Sbjct: 686 F----------PSPNSVSQLQNTIQQ 701
Score = 30.0 bits (66), Expect = 8.0
Identities = 43/196 (21%), Positives = 69/196 (35%), Gaps = 33/196 (16%)
Query: 63 PPQLQQQQQQQQQQQQQQPPHPLS--QLAQLQSQPVHPGLLHSSPTAFRAPPSSNSTAIL 120
P Q +QQ QQQ P + L+Q Q+QP GL PP+
Sbjct: 1093 PLQSTSNSEQQAAFQQQAPISHIQTPMLSQEQAQPPQQGLFQPQVALGSLPPNP------ 1146
Query: 121 HPSSRQGSQLNLNDHLLGHSPSSTATSGPGGGSRHRQASPLVHRRD-------SNPFTEI 173
P S+QG+ HS + ++ P + +Q ++ SN T
Sbjct: 1147 MPQSQQGTMFQSQ-----HSIVAMQSNSPSQEQQQQQQQQQQQQQQQQQSILFSNQNTMA 1201
Query: 174 AMSSCKYSGGVM------KPLSRLSASRRNLIEAET-------EGQPLQLFSPSNPPEIV 220
M+S K M P++ +++ ++ E QP+Q S S +
Sbjct: 1202 TMASPKQPPPNMIFNPNQNPMANQEQQNQSIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQ 1261
Query: 221 ISSREDNHAHQTLLHH 236
+ + QT L H
Sbjct: 1262 NPGPTQSESSQTPLFH 1277
>gi|5729945 nuclear factor of activated T-cells 5 isoform c [Homo
sapiens]
Length = 1531
Score = 59.3 bits (142), Expect = 1e-08
Identities = 75/257 (29%), Positives = 96/257 (37%), Gaps = 65/257 (25%)
Query: 24 PSSGDEQQQQQQQQQQQQPPPP---------APPAAPQQP-----LGPSLQPQPPQLQQQ 69
PS +QQQQQQQQQQQQ A A+P+QP P+ P Q QQ
Sbjct: 1246 PSQEQQQQQQQQQQQQQQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNPMANQEQQN 1305
Query: 70 QQQQQQQQQQQPPHPLSQLAQLQSQPV-----HPG----------LLHSSP--TAFRAPP 112
Q QQ P + Q Q QSQ +PG L HSSP + P
Sbjct: 1306 QSIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQNPGPTQSESSQTPLFHSSPQIQLVQGSP 1365
Query: 113 SSNS---TAILHPSSRQGSQLNLNDHLLGHSPSST----------ATSGP---------- 149
SS T L P+S Q ++N + SP + ATS P
Sbjct: 1366 SSQEQQVTLFLSPASMSALQTSINQQDMQQSPLYSPQNNMPGIQGATSSPQPQATLFHNT 1425
Query: 150 -GGGSRHRQASPLVHRRDSNPFTEIAMSSCKY---SGGVMKPLSRLSASRRNLIEAETEG 205
GG Q SP ++ S F ++C SG P ++ S+ + + EG
Sbjct: 1426 AGGTMNQLQNSPGSSQQTSGMFLFGIQNNCSQLLTSGPATLPDQLMAISQPG--QPQNEG 1483
Query: 206 QP-----LQLFSPSNPP 217
QP L P N P
Sbjct: 1484 QPPVTTLLSQQMPENSP 1500
Score = 50.4 bits (119), Expect = 6e-06
Identities = 58/248 (23%), Positives = 94/248 (37%), Gaps = 30/248 (12%)
Query: 30 QQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQ-----------------PQPPQLQQQQQQ 72
Q+Q Q QQ P A + P P+ S Q P Q QQQQQQ
Sbjct: 1198 QEQAQPPQQGLFQPQVALGSLPPNPMPQSQQGTMFQSQHSIVAMQSNSPSQEQQQQQQQQ 1257
Query: 73 QQQQQQQQP------PHPLSQLAQLQSQPVHPGLLHSSPTAFRAPPSSNSTAILHPSSRQ 126
QQQQQQQQ + ++ +A + P P ++ + A + +I H S
Sbjct: 1258 QQQQQQQQQSILFSNQNTMATMASPKQPP--PNMIFNPNQNPMANQEQQNQSIFHQQSNM 1315
Query: 127 GSQLNLNDHLLGHSPSSTATS--GPGGGSRHRQASPLVHRRDSNPFTEIAMSSCKYSGGV 184
+ +N + ST +S PG +PL H + + SS + +
Sbjct: 1316 -APMNQEQQPMQFQSQSTVSSLQNPGPTQSESSQTPLFHSSPQIQLVQGSPSSQEQQVTL 1374
Query: 185 MKPLSRLSASRRNLIEAETEGQPLQLFSPSNPPEIVISSREDNHAHQTLLHHPNATHNHQ 244
+ +SA + ++ + + + P L+SP N + + TL H+ +Q
Sbjct: 1375 FLSPASMSALQTSINQQDMQQSP--LYSPQNNMPGIQGATSSPQPQATLFHNTAGGTMNQ 1432
Query: 245 HAGTTASS 252
+ SS
Sbjct: 1433 LQNSPGSS 1440
Score = 38.1 bits (87), Expect = 0.029
Identities = 57/251 (22%), Positives = 87/251 (34%), Gaps = 24/251 (9%)
Query: 24 PSSGDEQQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQ---------QQQQQ 74
P S + QQQQQQQQQ + AA + S+ Q+Q + QQ
Sbjct: 870 PQSENTLSNQQQQQQQQQQVMES-SAAMVMEMQQSICQAAAQIQSELFPSTASANGNLQQ 928
Query: 75 QQQQQQPPHPLSQLAQLQSQPVHPGLLHSSP---------TAFRAPPSSNSTAILHPSSR 125
QQ H +S L+ + + L S P T + + +T SS
Sbjct: 929 SPVYQQTSHMMSALSTNEDMQMQCELFSSPPAVSGNETSTTTTQQVATPGTTMFQTSSSG 988
Query: 126 QGSQLNLNDHLLGHSPSSTATSGPGGGSRHRQASPLVHRRDSNPFTEIAMSSCKYSGGVM 185
G + + +S T G Q + L S + + + + +G
Sbjct: 989 DGEETGTQAKQIQNSVFQTMVQMQHSGDNQPQVN-LFSSTKSMMSVQNSGTQQQGNGLFQ 1047
Query: 186 KPLSRLSASRRNLIEAETEGQPLQLFSPSNPPEIVISSREDNHAHQTLLHHPNATHNHQH 245
+ +S N ++ + Q QLF P NP I + +L H PN H
Sbjct: 1048 QGNEMMSLQSGNFLQQSSHSQ-AQLFHPQNP--IADAQNLSQETQGSLFHSPNPI-VHSQ 1103
Query: 246 AGTTASSTTFP 256
TT+S P
Sbjct: 1104 TSTTSSEQMQP 1114
Score = 31.2 bits (69), Expect = 3.6
Identities = 36/146 (24%), Positives = 51/146 (34%), Gaps = 39/146 (26%)
Query: 10 SGVGDLDEDPKCPCPSSGDEQQQQQ------------QQQQQQQPPP-PAPPAAPQQPLG 56
+G G PS ++QQQ Q Q Q QP PA A+ Q P
Sbjct: 642 AGNGSFSSPSSSHLPSENEKQQQIQPKAYNPETLTTIQTQDISQPGTFPAVSASSQLPNS 701
Query: 57 PSLQPQPPQLQQQQQQQQQ----------------QQQQQPPHPLSQLAQLQSQPVHPGL 100
+L Q Q Q ++ Q ++ QQQ PL + AQ Q + +
Sbjct: 702 DALLQQATQFQTRETQSREILQSDGTVVNLSQLTEASQQQQQSPLQEQAQTLQQQISSNI 761
Query: 101 LHSSPTAFRAPPSSNSTAILHPSSRQ 126
PS NS + L + +Q
Sbjct: 762 F----------PSPNSVSQLQNTIQQ 777
Score = 30.0 bits (66), Expect = 8.0
Identities = 43/196 (21%), Positives = 69/196 (35%), Gaps = 33/196 (16%)
Query: 63 PPQLQQQQQQQQQQQQQQPPHPLS--QLAQLQSQPVHPGLLHSSPTAFRAPPSSNSTAIL 120
P Q +QQ QQQ P + L+Q Q+QP GL PP+
Sbjct: 1169 PLQSTSNSEQQAAFQQQAPISHIQTPMLSQEQAQPPQQGLFQPQVALGSLPPNP------ 1222
Query: 121 HPSSRQGSQLNLNDHLLGHSPSSTATSGPGGGSRHRQASPLVHRRD-------SNPFTEI 173
P S+QG+ HS + ++ P + +Q ++ SN T
Sbjct: 1223 MPQSQQGTMFQSQ-----HSIVAMQSNSPSQEQQQQQQQQQQQQQQQQQSILFSNQNTMA 1277
Query: 174 AMSSCKYSGGVM------KPLSRLSASRRNLIEAET-------EGQPLQLFSPSNPPEIV 220
M+S K M P++ +++ ++ E QP+Q S S +
Sbjct: 1278 TMASPKQPPPNMIFNPNQNPMANQEQQNQSIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQ 1337
Query: 221 ISSREDNHAHQTLLHH 236
+ + QT L H
Sbjct: 1338 NPGPTQSESSQTPLFH 1353
>gi|164419746 nuclear factor of activated T-cells 5 isoform d [Homo
sapiens]
Length = 1548
Score = 59.3 bits (142), Expect = 1e-08
Identities = 75/257 (29%), Positives = 96/257 (37%), Gaps = 65/257 (25%)
Query: 24 PSSGDEQQQQQQQQQQQQPPPP---------APPAAPQQP-----LGPSLQPQPPQLQQQ 69
PS +QQQQQQQQQQQQ A A+P+QP P+ P Q QQ
Sbjct: 1263 PSQEQQQQQQQQQQQQQQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNPMANQEQQN 1322
Query: 70 QQQQQQQQQQQPPHPLSQLAQLQSQPV-----HPG----------LLHSSP--TAFRAPP 112
Q QQ P + Q Q QSQ +PG L HSSP + P
Sbjct: 1323 QSIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQNPGPTQSESSQTPLFHSSPQIQLVQGSP 1382
Query: 113 SSNS---TAILHPSSRQGSQLNLNDHLLGHSPSST----------ATSGP---------- 149
SS T L P+S Q ++N + SP + ATS P
Sbjct: 1383 SSQEQQVTLFLSPASMSALQTSINQQDMQQSPLYSPQNNMPGIQGATSSPQPQATLFHNT 1442
Query: 150 -GGGSRHRQASPLVHRRDSNPFTEIAMSSCKY---SGGVMKPLSRLSASRRNLIEAETEG 205
GG Q SP ++ S F ++C SG P ++ S+ + + EG
Sbjct: 1443 AGGTMNQLQNSPGSSQQTSGMFLFGIQNNCSQLLTSGPATLPDQLMAISQPG--QPQNEG 1500
Query: 206 QP-----LQLFSPSNPP 217
QP L P N P
Sbjct: 1501 QPPVTTLLSQQMPENSP 1517
Score = 50.4 bits (119), Expect = 6e-06
Identities = 58/248 (23%), Positives = 94/248 (37%), Gaps = 30/248 (12%)
Query: 30 QQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQ-----------------PQPPQLQQQQQQ 72
Q+Q Q QQ P A + P P+ S Q P Q QQQQQQ
Sbjct: 1215 QEQAQPPQQGLFQPQVALGSLPPNPMPQSQQGTMFQSQHSIVAMQSNSPSQEQQQQQQQQ 1274
Query: 73 QQQQQQQQP------PHPLSQLAQLQSQPVHPGLLHSSPTAFRAPPSSNSTAILHPSSRQ 126
QQQQQQQQ + ++ +A + P P ++ + A + +I H S
Sbjct: 1275 QQQQQQQQQSILFSNQNTMATMASPKQPP--PNMIFNPNQNPMANQEQQNQSIFHQQSNM 1332
Query: 127 GSQLNLNDHLLGHSPSSTATS--GPGGGSRHRQASPLVHRRDSNPFTEIAMSSCKYSGGV 184
+ +N + ST +S PG +PL H + + SS + +
Sbjct: 1333 -APMNQEQQPMQFQSQSTVSSLQNPGPTQSESSQTPLFHSSPQIQLVQGSPSSQEQQVTL 1391
Query: 185 MKPLSRLSASRRNLIEAETEGQPLQLFSPSNPPEIVISSREDNHAHQTLLHHPNATHNHQ 244
+ +SA + ++ + + + P L+SP N + + TL H+ +Q
Sbjct: 1392 FLSPASMSALQTSINQQDMQQSP--LYSPQNNMPGIQGATSSPQPQATLFHNTAGGTMNQ 1449
Query: 245 HAGTTASS 252
+ SS
Sbjct: 1450 LQNSPGSS 1457
Score = 38.1 bits (87), Expect = 0.029
Identities = 57/251 (22%), Positives = 87/251 (34%), Gaps = 24/251 (9%)
Query: 24 PSSGDEQQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQ---------QQQQQ 74
P S + QQQQQQQQQ + AA + S+ Q+Q + QQ
Sbjct: 887 PQSENTLSNQQQQQQQQQQVMES-SAAMVMEMQQSICQAAAQIQSELFPSTASANGNLQQ 945
Query: 75 QQQQQQPPHPLSQLAQLQSQPVHPGLLHSSP---------TAFRAPPSSNSTAILHPSSR 125
QQ H +S L+ + + L S P T + + +T SS
Sbjct: 946 SPVYQQTSHMMSALSTNEDMQMQCELFSSPPAVSGNETSTTTTQQVATPGTTMFQTSSSG 1005
Query: 126 QGSQLNLNDHLLGHSPSSTATSGPGGGSRHRQASPLVHRRDSNPFTEIAMSSCKYSGGVM 185
G + + +S T G Q + L S + + + + +G
Sbjct: 1006 DGEETGTQAKQIQNSVFQTMVQMQHSGDNQPQVN-LFSSTKSMMSVQNSGTQQQGNGLFQ 1064
Query: 186 KPLSRLSASRRNLIEAETEGQPLQLFSPSNPPEIVISSREDNHAHQTLLHHPNATHNHQH 245
+ +S N ++ + Q QLF P NP I + +L H PN H
Sbjct: 1065 QGNEMMSLQSGNFLQQSSHSQ-AQLFHPQNP--IADAQNLSQETQGSLFHSPNPI-VHSQ 1120
Query: 246 AGTTASSTTFP 256
TT+S P
Sbjct: 1121 TSTTSSEQMQP 1131
Score = 31.2 bits (69), Expect = 3.6
Identities = 36/146 (24%), Positives = 51/146 (34%), Gaps = 39/146 (26%)
Query: 10 SGVGDLDEDPKCPCPSSGDEQQQQQ------------QQQQQQQPPP-PAPPAAPQQPLG 56
+G G PS ++QQQ Q Q Q QP PA A+ Q P
Sbjct: 659 AGNGSFSSPSSSHLPSENEKQQQIQPKAYNPETLTTIQTQDISQPGTFPAVSASSQLPNS 718
Query: 57 PSLQPQPPQLQQQQQQQQQ----------------QQQQQPPHPLSQLAQLQSQPVHPGL 100
+L Q Q Q ++ Q ++ QQQ PL + AQ Q + +
Sbjct: 719 DALLQQATQFQTRETQSREILQSDGTVVNLSQLTEASQQQQQSPLQEQAQTLQQQISSNI 778
Query: 101 LHSSPTAFRAPPSSNSTAILHPSSRQ 126
PS NS + L + +Q
Sbjct: 779 F----------PSPNSVSQLQNTIQQ 794
Score = 30.0 bits (66), Expect = 8.0
Identities = 43/196 (21%), Positives = 69/196 (35%), Gaps = 33/196 (16%)
Query: 63 PPQLQQQQQQQQQQQQQQPPHPLS--QLAQLQSQPVHPGLLHSSPTAFRAPPSSNSTAIL 120
P Q +QQ QQQ P + L+Q Q+QP GL PP+
Sbjct: 1186 PLQSTSNSEQQAAFQQQAPISHIQTPMLSQEQAQPPQQGLFQPQVALGSLPPNP------ 1239
Query: 121 HPSSRQGSQLNLNDHLLGHSPSSTATSGPGGGSRHRQASPLVHRRD-------SNPFTEI 173
P S+QG+ HS + ++ P + +Q ++ SN T
Sbjct: 1240 MPQSQQGTMFQSQ-----HSIVAMQSNSPSQEQQQQQQQQQQQQQQQQQSILFSNQNTMA 1294
Query: 174 AMSSCKYSGGVM------KPLSRLSASRRNLIEAET-------EGQPLQLFSPSNPPEIV 220
M+S K M P++ +++ ++ E QP+Q S S +
Sbjct: 1295 TMASPKQPPPNMIFNPNQNPMANQEQQNQSIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQ 1354
Query: 221 ISSREDNHAHQTLLHH 236
+ + QT L H
Sbjct: 1355 NPGPTQSESSQTPLFH 1370
>gi|164419744 nuclear factor of activated T-cells 5 isoform b [Homo
sapiens]
Length = 1549
Score = 59.3 bits (142), Expect = 1e-08
Identities = 75/257 (29%), Positives = 96/257 (37%), Gaps = 65/257 (25%)
Query: 24 PSSGDEQQQQQQQQQQQQPPPP---------APPAAPQQP-----LGPSLQPQPPQLQQQ 69
PS +QQQQQQQQQQQQ A A+P+QP P+ P Q QQ
Sbjct: 1264 PSQEQQQQQQQQQQQQQQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNPMANQEQQN 1323
Query: 70 QQQQQQQQQQQPPHPLSQLAQLQSQPV-----HPG----------LLHSSP--TAFRAPP 112
Q QQ P + Q Q QSQ +PG L HSSP + P
Sbjct: 1324 QSIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQNPGPTQSESSQTPLFHSSPQIQLVQGSP 1383
Query: 113 SSNS---TAILHPSSRQGSQLNLNDHLLGHSPSST----------ATSGP---------- 149
SS T L P+S Q ++N + SP + ATS P
Sbjct: 1384 SSQEQQVTLFLSPASMSALQTSINQQDMQQSPLYSPQNNMPGIQGATSSPQPQATLFHNT 1443
Query: 150 -GGGSRHRQASPLVHRRDSNPFTEIAMSSCKY---SGGVMKPLSRLSASRRNLIEAETEG 205
GG Q SP ++ S F ++C SG P ++ S+ + + EG
Sbjct: 1444 AGGTMNQLQNSPGSSQQTSGMFLFGIQNNCSQLLTSGPATLPDQLMAISQPG--QPQNEG 1501
Query: 206 QP-----LQLFSPSNPP 217
QP L P N P
Sbjct: 1502 QPPVTTLLSQQMPENSP 1518
Score = 50.4 bits (119), Expect = 6e-06
Identities = 58/248 (23%), Positives = 94/248 (37%), Gaps = 30/248 (12%)
Query: 30 QQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQ-----------------PQPPQLQQQQQQ 72
Q+Q Q QQ P A + P P+ S Q P Q QQQQQQ
Sbjct: 1216 QEQAQPPQQGLFQPQVALGSLPPNPMPQSQQGTMFQSQHSIVAMQSNSPSQEQQQQQQQQ 1275
Query: 73 QQQQQQQQP------PHPLSQLAQLQSQPVHPGLLHSSPTAFRAPPSSNSTAILHPSSRQ 126
QQQQQQQQ + ++ +A + P P ++ + A + +I H S
Sbjct: 1276 QQQQQQQQQSILFSNQNTMATMASPKQPP--PNMIFNPNQNPMANQEQQNQSIFHQQSNM 1333
Query: 127 GSQLNLNDHLLGHSPSSTATS--GPGGGSRHRQASPLVHRRDSNPFTEIAMSSCKYSGGV 184
+ +N + ST +S PG +PL H + + SS + +
Sbjct: 1334 -APMNQEQQPMQFQSQSTVSSLQNPGPTQSESSQTPLFHSSPQIQLVQGSPSSQEQQVTL 1392
Query: 185 MKPLSRLSASRRNLIEAETEGQPLQLFSPSNPPEIVISSREDNHAHQTLLHHPNATHNHQ 244
+ +SA + ++ + + + P L+SP N + + TL H+ +Q
Sbjct: 1393 FLSPASMSALQTSINQQDMQQSP--LYSPQNNMPGIQGATSSPQPQATLFHNTAGGTMNQ 1450
Query: 245 HAGTTASS 252
+ SS
Sbjct: 1451 LQNSPGSS 1458
Score = 38.1 bits (87), Expect = 0.029
Identities = 57/251 (22%), Positives = 87/251 (34%), Gaps = 24/251 (9%)
Query: 24 PSSGDEQQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQ---------QQQQQ 74
P S + QQQQQQQQQ + AA + S+ Q+Q + QQ
Sbjct: 888 PQSENTLSNQQQQQQQQQQVMES-SAAMVMEMQQSICQAAAQIQSELFPSTASANGNLQQ 946
Query: 75 QQQQQQPPHPLSQLAQLQSQPVHPGLLHSSP---------TAFRAPPSSNSTAILHPSSR 125
QQ H +S L+ + + L S P T + + +T SS
Sbjct: 947 SPVYQQTSHMMSALSTNEDMQMQCELFSSPPAVSGNETSTTTTQQVATPGTTMFQTSSSG 1006
Query: 126 QGSQLNLNDHLLGHSPSSTATSGPGGGSRHRQASPLVHRRDSNPFTEIAMSSCKYSGGVM 185
G + + +S T G Q + L S + + + + +G
Sbjct: 1007 DGEETGTQAKQIQNSVFQTMVQMQHSGDNQPQVN-LFSSTKSMMSVQNSGTQQQGNGLFQ 1065
Query: 186 KPLSRLSASRRNLIEAETEGQPLQLFSPSNPPEIVISSREDNHAHQTLLHHPNATHNHQH 245
+ +S N ++ + Q QLF P NP I + +L H PN H
Sbjct: 1066 QGNEMMSLQSGNFLQQSSHSQ-AQLFHPQNP--IADAQNLSQETQGSLFHSPNPI-VHSQ 1121
Query: 246 AGTTASSTTFP 256
TT+S P
Sbjct: 1122 TSTTSSEQMQP 1132
Score = 31.2 bits (69), Expect = 3.6
Identities = 36/146 (24%), Positives = 51/146 (34%), Gaps = 39/146 (26%)
Query: 10 SGVGDLDEDPKCPCPSSGDEQQQQQ------------QQQQQQQPPP-PAPPAAPQQPLG 56
+G G PS ++QQQ Q Q Q QP PA A+ Q P
Sbjct: 660 AGNGSFSSPSSSHLPSENEKQQQIQPKAYNPETLTTIQTQDISQPGTFPAVSASSQLPNS 719
Query: 57 PSLQPQPPQLQQQQQQQQQ----------------QQQQQPPHPLSQLAQLQSQPVHPGL 100
+L Q Q Q ++ Q ++ QQQ PL + AQ Q + +
Sbjct: 720 DALLQQATQFQTRETQSREILQSDGTVVNLSQLTEASQQQQQSPLQEQAQTLQQQISSNI 779
Query: 101 LHSSPTAFRAPPSSNSTAILHPSSRQ 126
PS NS + L + +Q
Sbjct: 780 F----------PSPNSVSQLQNTIQQ 795
Score = 30.0 bits (66), Expect = 8.0
Identities = 43/196 (21%), Positives = 69/196 (35%), Gaps = 33/196 (16%)
Query: 63 PPQLQQQQQQQQQQQQQQPPHPLS--QLAQLQSQPVHPGLLHSSPTAFRAPPSSNSTAIL 120
P Q +QQ QQQ P + L+Q Q+QP GL PP+
Sbjct: 1187 PLQSTSNSEQQAAFQQQAPISHIQTPMLSQEQAQPPQQGLFQPQVALGSLPPNP------ 1240
Query: 121 HPSSRQGSQLNLNDHLLGHSPSSTATSGPGGGSRHRQASPLVHRRD-------SNPFTEI 173
P S+QG+ HS + ++ P + +Q ++ SN T
Sbjct: 1241 MPQSQQGTMFQSQ-----HSIVAMQSNSPSQEQQQQQQQQQQQQQQQQQSILFSNQNTMA 1295
Query: 174 AMSSCKYSGGVM------KPLSRLSASRRNLIEAET-------EGQPLQLFSPSNPPEIV 220
M+S K M P++ +++ ++ E QP+Q S S +
Sbjct: 1296 TMASPKQPPPNMIFNPNQNPMANQEQQNQSIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQ 1355
Query: 221 ISSREDNHAHQTLLHH 236
+ + QT L H
Sbjct: 1356 NPGPTQSESSQTPLFH 1371
>gi|27886524 nuclear factor of activated T-cells 5 isoform a [Homo
sapiens]
Length = 1455
Score = 59.3 bits (142), Expect = 1e-08
Identities = 75/257 (29%), Positives = 96/257 (37%), Gaps = 65/257 (25%)
Query: 24 PSSGDEQQQQQQQQQQQQPPPP---------APPAAPQQP-----LGPSLQPQPPQLQQQ 69
PS +QQQQQQQQQQQQ A A+P+QP P+ P Q QQ
Sbjct: 1170 PSQEQQQQQQQQQQQQQQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNPMANQEQQN 1229
Query: 70 QQQQQQQQQQQPPHPLSQLAQLQSQPV-----HPG----------LLHSSP--TAFRAPP 112
Q QQ P + Q Q QSQ +PG L HSSP + P
Sbjct: 1230 QSIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQNPGPTQSESSQTPLFHSSPQIQLVQGSP 1289
Query: 113 SSNS---TAILHPSSRQGSQLNLNDHLLGHSPSST----------ATSGP---------- 149
SS T L P+S Q ++N + SP + ATS P
Sbjct: 1290 SSQEQQVTLFLSPASMSALQTSINQQDMQQSPLYSPQNNMPGIQGATSSPQPQATLFHNT 1349
Query: 150 -GGGSRHRQASPLVHRRDSNPFTEIAMSSCKY---SGGVMKPLSRLSASRRNLIEAETEG 205
GG Q SP ++ S F ++C SG P ++ S+ + + EG
Sbjct: 1350 AGGTMNQLQNSPGSSQQTSGMFLFGIQNNCSQLLTSGPATLPDQLMAISQPG--QPQNEG 1407
Query: 206 QP-----LQLFSPSNPP 217
QP L P N P
Sbjct: 1408 QPPVTTLLSQQMPENSP 1424
Score = 50.4 bits (119), Expect = 6e-06
Identities = 58/248 (23%), Positives = 94/248 (37%), Gaps = 30/248 (12%)
Query: 30 QQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQ-----------------PQPPQLQQQQQQ 72
Q+Q Q QQ P A + P P+ S Q P Q QQQQQQ
Sbjct: 1122 QEQAQPPQQGLFQPQVALGSLPPNPMPQSQQGTMFQSQHSIVAMQSNSPSQEQQQQQQQQ 1181
Query: 73 QQQQQQQQP------PHPLSQLAQLQSQPVHPGLLHSSPTAFRAPPSSNSTAILHPSSRQ 126
QQQQQQQQ + ++ +A + P P ++ + A + +I H S
Sbjct: 1182 QQQQQQQQQSILFSNQNTMATMASPKQPP--PNMIFNPNQNPMANQEQQNQSIFHQQSNM 1239
Query: 127 GSQLNLNDHLLGHSPSSTATS--GPGGGSRHRQASPLVHRRDSNPFTEIAMSSCKYSGGV 184
+ +N + ST +S PG +PL H + + SS + +
Sbjct: 1240 -APMNQEQQPMQFQSQSTVSSLQNPGPTQSESSQTPLFHSSPQIQLVQGSPSSQEQQVTL 1298
Query: 185 MKPLSRLSASRRNLIEAETEGQPLQLFSPSNPPEIVISSREDNHAHQTLLHHPNATHNHQ 244
+ +SA + ++ + + + P L+SP N + + TL H+ +Q
Sbjct: 1299 FLSPASMSALQTSINQQDMQQSP--LYSPQNNMPGIQGATSSPQPQATLFHNTAGGTMNQ 1356
Query: 245 HAGTTASS 252
+ SS
Sbjct: 1357 LQNSPGSS 1364
Score = 38.1 bits (87), Expect = 0.029
Identities = 57/251 (22%), Positives = 87/251 (34%), Gaps = 24/251 (9%)
Query: 24 PSSGDEQQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQ---------QQQQQ 74
P S + QQQQQQQQQ + AA + S+ Q+Q + QQ
Sbjct: 794 PQSENTLSNQQQQQQQQQQVMES-SAAMVMEMQQSICQAAAQIQSELFPSTASANGNLQQ 852
Query: 75 QQQQQQPPHPLSQLAQLQSQPVHPGLLHSSP---------TAFRAPPSSNSTAILHPSSR 125
QQ H +S L+ + + L S P T + + +T SS
Sbjct: 853 SPVYQQTSHMMSALSTNEDMQMQCELFSSPPAVSGNETSTTTTQQVATPGTTMFQTSSSG 912
Query: 126 QGSQLNLNDHLLGHSPSSTATSGPGGGSRHRQASPLVHRRDSNPFTEIAMSSCKYSGGVM 185
G + + +S T G Q + L S + + + + +G
Sbjct: 913 DGEETGTQAKQIQNSVFQTMVQMQHSGDNQPQVN-LFSSTKSMMSVQNSGTQQQGNGLFQ 971
Query: 186 KPLSRLSASRRNLIEAETEGQPLQLFSPSNPPEIVISSREDNHAHQTLLHHPNATHNHQH 245
+ +S N ++ + Q QLF P NP I + +L H PN H
Sbjct: 972 QGNEMMSLQSGNFLQQSSHSQ-AQLFHPQNP--IADAQNLSQETQGSLFHSPNPI-VHSQ 1027
Query: 246 AGTTASSTTFP 256
TT+S P
Sbjct: 1028 TSTTSSEQMQP 1038
Score = 31.2 bits (69), Expect = 3.6
Identities = 36/146 (24%), Positives = 51/146 (34%), Gaps = 39/146 (26%)
Query: 10 SGVGDLDEDPKCPCPSSGDEQQQQQ------------QQQQQQQPPP-PAPPAAPQQPLG 56
+G G PS ++QQQ Q Q Q QP PA A+ Q P
Sbjct: 566 AGNGSFSSPSSSHLPSENEKQQQIQPKAYNPETLTTIQTQDISQPGTFPAVSASSQLPNS 625
Query: 57 PSLQPQPPQLQQQQQQQQQ----------------QQQQQPPHPLSQLAQLQSQPVHPGL 100
+L Q Q Q ++ Q ++ QQQ PL + AQ Q + +
Sbjct: 626 DALLQQATQFQTRETQSREILQSDGTVVNLSQLTEASQQQQQSPLQEQAQTLQQQISSNI 685
Query: 101 LHSSPTAFRAPPSSNSTAILHPSSRQ 126
PS NS + L + +Q
Sbjct: 686 F----------PSPNSVSQLQNTIQQ 701
Score = 30.0 bits (66), Expect = 8.0
Identities = 43/196 (21%), Positives = 69/196 (35%), Gaps = 33/196 (16%)
Query: 63 PPQLQQQQQQQQQQQQQQPPHPLS--QLAQLQSQPVHPGLLHSSPTAFRAPPSSNSTAIL 120
P Q +QQ QQQ P + L+Q Q+QP GL PP+
Sbjct: 1093 PLQSTSNSEQQAAFQQQAPISHIQTPMLSQEQAQPPQQGLFQPQVALGSLPPNP------ 1146
Query: 121 HPSSRQGSQLNLNDHLLGHSPSSTATSGPGGGSRHRQASPLVHRRD-------SNPFTEI 173
P S+QG+ HS + ++ P + +Q ++ SN T
Sbjct: 1147 MPQSQQGTMFQSQ-----HSIVAMQSNSPSQEQQQQQQQQQQQQQQQQQSILFSNQNTMA 1201
Query: 174 AMSSCKYSGGVM------KPLSRLSASRRNLIEAET-------EGQPLQLFSPSNPPEIV 220
M+S K M P++ +++ ++ E QP+Q S S +
Sbjct: 1202 TMASPKQPPPNMIFNPNQNPMANQEQQNQSIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQ 1261
Query: 221 ISSREDNHAHQTLLHH 236
+ + QT L H
Sbjct: 1262 NPGPTQSESSQTPLFH 1277
>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 58.9 bits (141), Expect = 2e-08
Identities = 28/53 (52%), Positives = 30/53 (56%)
Query: 32 QQQQQQQQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQQQQQQQQPPHP 84
++ QQQQPPPP P P P PQPP QQQ QQQ Q Q QQPP P
Sbjct: 1641 ERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQQQPQPQPQQPPPP 1693
Score = 58.5 bits (140), Expect = 2e-08
Identities = 30/64 (46%), Positives = 33/64 (51%)
Query: 24 PSSGDEQQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQQQQQQQQPPH 83
P S ++ QQQQ PPPP P P P+ QP PPQ Q QQQ Q Q QQ PP
Sbjct: 1635 PQSCVVERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQQQPQPQPQQPPPPP 1694
Query: 84 PLSQ 87
P Q
Sbjct: 1695 PPQQ 1698
Score = 40.0 bits (92), Expect = 0.008
Identities = 40/150 (26%), Positives = 57/150 (38%), Gaps = 29/150 (19%)
Query: 22 PCPSSGDEQQQQQQQQQQQQPPPPAPPAAPQQP------LGPSLQPQPPQLQQQQQQQQ- 74
P P +Q QQQ Q Q QQPPPP PP QQP + S P P ++ +
Sbjct: 1670 PQPPPPQQQPQQQPQPQPQQPPPPPPP--QQQPPLSQCSMNNSFTPAPMIMEIPESGSTG 1727
Query: 75 ---------------QQQQQQPPHPLSQLAQLQSQPVHPGLLHSSPTAFRAPPSSNSTAI 119
Q L++L QL + + P H+ P + +S +T++
Sbjct: 1728 NISIYERIPGDFGAGSYSQPSATFSLAKLQQLTNTIMDP---HAMPYSHSPAVTSYATSV 1784
Query: 120 LHPSSRQGSQLNLNDHLLGHSPSSTATSGP 149
S G H L +P + AT P
Sbjct: 1785 --SLSNTGLAQLAPSHPLAGTPQAQATMTP 1812
Score = 35.0 bits (79), Expect = 0.25
Identities = 34/132 (25%), Positives = 47/132 (35%), Gaps = 10/132 (7%)
Query: 17 EDPKCPCPSSGDEQQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQQQQ 76
+ P+ P P Q QQQ QQ P P PQQP P PP QQ Q
Sbjct: 1657 QQPQPPPPQPQPAPQPPPPQQQPQQQPQP----QPQQP-----PPPPPPQQQPPLSQCSM 1707
Query: 77 QQQQPPHPLSQLAQLQSQPVHPGLLHSSPTAFRAPPSSNSTAILHPSS-RQGSQLNLNDH 135
P P+ + + P F A S +A + +Q + ++ H
Sbjct: 1708 NNSFTPAPMIMEIPESGSTGNISIYERIPGDFGAGSYSQPSATFSLAKLQQLTNTIMDPH 1767
Query: 136 LLGHSPSSTATS 147
+ +S S TS
Sbjct: 1768 AMPYSHSPAVTS 1779
Score = 34.3 bits (77), Expect = 0.42
Identities = 28/85 (32%), Positives = 30/85 (35%), Gaps = 7/85 (8%)
Query: 36 QQQQQQPPPPAPPAAPQQ------PLGPSLQPQPPQLQQQQQQQQQQQQQQPPHPLSQLA 89
QQ QP +PQ P QP PP QQ Q Q Q P P Q
Sbjct: 1620 QQSSVQPAANCSIKSPQSCVVERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQP 1679
Query: 90 QLQSQPVHPGLLHSSPTAFRAPPSS 114
Q Q QP P P + PP S
Sbjct: 1680 QQQPQP-QPQQPPPPPPPQQQPPLS 1703
>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 58.9 bits (141), Expect = 2e-08
Identities = 28/53 (52%), Positives = 30/53 (56%)
Query: 32 QQQQQQQQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQQQQQQQQPPHP 84
++ QQQQPPPP P P P PQPP QQQ QQQ Q Q QQPP P
Sbjct: 1641 ERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQQQPQPQPQQPPPP 1693
Score = 58.5 bits (140), Expect = 2e-08
Identities = 30/64 (46%), Positives = 33/64 (51%)
Query: 24 PSSGDEQQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQQQQQQQQPPH 83
P S ++ QQQQ PPPP P P P+ QP PPQ Q QQQ Q Q QQ PP
Sbjct: 1635 PQSCVVERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQQQPQPQPQQPPPPP 1694
Query: 84 PLSQ 87
P Q
Sbjct: 1695 PPQQ 1698
Score = 40.0 bits (92), Expect = 0.008
Identities = 40/150 (26%), Positives = 57/150 (38%), Gaps = 29/150 (19%)
Query: 22 PCPSSGDEQQQQQQQQQQQQPPPPAPPAAPQQP------LGPSLQPQPPQLQQQQQQQQ- 74
P P +Q QQQ Q Q QQPPPP PP QQP + S P P ++ +
Sbjct: 1670 PQPPPPQQQPQQQPQPQPQQPPPPPPP--QQQPPLSQCSMNNSFTPAPMIMEIPESGSTG 1727
Query: 75 ---------------QQQQQQPPHPLSQLAQLQSQPVHPGLLHSSPTAFRAPPSSNSTAI 119
Q L++L QL + + P H+ P + +S +T++
Sbjct: 1728 NISIYERIPGDFGAGSYSQPSATFSLAKLQQLTNTIMDP---HAMPYSHSPAVTSYATSV 1784
Query: 120 LHPSSRQGSQLNLNDHLLGHSPSSTATSGP 149
S G H L +P + AT P
Sbjct: 1785 --SLSNTGLAQLAPSHPLAGTPQAQATMTP 1812
Score = 35.0 bits (79), Expect = 0.25
Identities = 34/132 (25%), Positives = 47/132 (35%), Gaps = 10/132 (7%)
Query: 17 EDPKCPCPSSGDEQQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQQQQ 76
+ P+ P P Q QQQ QQ P P PQQP P PP QQ Q
Sbjct: 1657 QQPQPPPPQPQPAPQPPPPQQQPQQQPQP----QPQQP-----PPPPPPQQQPPLSQCSM 1707
Query: 77 QQQQPPHPLSQLAQLQSQPVHPGLLHSSPTAFRAPPSSNSTAILHPSS-RQGSQLNLNDH 135
P P+ + + P F A S +A + +Q + ++ H
Sbjct: 1708 NNSFTPAPMIMEIPESGSTGNISIYERIPGDFGAGSYSQPSATFSLAKLQQLTNTIMDPH 1767
Query: 136 LLGHSPSSTATS 147
+ +S S TS
Sbjct: 1768 AMPYSHSPAVTS 1779
Score = 34.3 bits (77), Expect = 0.42
Identities = 28/85 (32%), Positives = 30/85 (35%), Gaps = 7/85 (8%)
Query: 36 QQQQQQPPPPAPPAAPQQ------PLGPSLQPQPPQLQQQQQQQQQQQQQQPPHPLSQLA 89
QQ QP +PQ P QP PP QQ Q Q Q P P Q
Sbjct: 1620 QQSSVQPAANCSIKSPQSCVVERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQP 1679
Query: 90 QLQSQPVHPGLLHSSPTAFRAPPSS 114
Q Q QP P P + PP S
Sbjct: 1680 QQQPQP-QPQQPPPPPPPQQQPPLS 1703
>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 58.9 bits (141), Expect = 2e-08
Identities = 28/53 (52%), Positives = 30/53 (56%)
Query: 32 QQQQQQQQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQQQQQQQQPPHP 84
++ QQQQPPPP P P P PQPP QQQ QQQ Q Q QQPP P
Sbjct: 1641 ERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQQQPQPQPQQPPPP 1693
Score = 58.5 bits (140), Expect = 2e-08
Identities = 30/64 (46%), Positives = 33/64 (51%)
Query: 24 PSSGDEQQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQQQQQQQQPPH 83
P S ++ QQQQ PPPP P P P+ QP PPQ Q QQQ Q Q QQ PP
Sbjct: 1635 PQSCVVERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQPQQQPQPQPQQPPPPP 1694
Query: 84 PLSQ 87
P Q
Sbjct: 1695 PPQQ 1698
Score = 40.0 bits (92), Expect = 0.008
Identities = 40/150 (26%), Positives = 57/150 (38%), Gaps = 29/150 (19%)
Query: 22 PCPSSGDEQQQQQQQQQQQQPPPPAPPAAPQQP------LGPSLQPQPPQLQQQQQQQQ- 74
P P +Q QQQ Q Q QQPPPP PP QQP + S P P ++ +
Sbjct: 1670 PQPPPPQQQPQQQPQPQPQQPPPPPPP--QQQPPLSQCSMNNSFTPAPMIMEIPESGSTG 1727
Query: 75 ---------------QQQQQQPPHPLSQLAQLQSQPVHPGLLHSSPTAFRAPPSSNSTAI 119
Q L++L QL + + P H+ P + +S +T++
Sbjct: 1728 NISIYERIPGDFGAGSYSQPSATFSLAKLQQLTNTIMDP---HAMPYSHSPAVTSYATSV 1784
Query: 120 LHPSSRQGSQLNLNDHLLGHSPSSTATSGP 149
S G H L +P + AT P
Sbjct: 1785 --SLSNTGLAQLAPSHPLAGTPQAQATMTP 1812
Score = 35.0 bits (79), Expect = 0.25
Identities = 34/132 (25%), Positives = 47/132 (35%), Gaps = 10/132 (7%)
Query: 17 EDPKCPCPSSGDEQQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQQQQ 76
+ P+ P P Q QQQ QQ P P PQQP P PP QQ Q
Sbjct: 1657 QQPQPPPPQPQPAPQPPPPQQQPQQQPQP----QPQQP-----PPPPPPQQQPPLSQCSM 1707
Query: 77 QQQQPPHPLSQLAQLQSQPVHPGLLHSSPTAFRAPPSSNSTAILHPSS-RQGSQLNLNDH 135
P P+ + + P F A S +A + +Q + ++ H
Sbjct: 1708 NNSFTPAPMIMEIPESGSTGNISIYERIPGDFGAGSYSQPSATFSLAKLQQLTNTIMDPH 1767
Query: 136 LLGHSPSSTATS 147
+ +S S TS
Sbjct: 1768 AMPYSHSPAVTS 1779
Score = 34.3 bits (77), Expect = 0.42
Identities = 28/85 (32%), Positives = 30/85 (35%), Gaps = 7/85 (8%)
Query: 36 QQQQQQPPPPAPPAAPQQ------PLGPSLQPQPPQLQQQQQQQQQQQQQQPPHPLSQLA 89
QQ QP +PQ P QP PP QQ Q Q Q P P Q
Sbjct: 1620 QQSSVQPAANCSIKSPQSCVVERPPSNQQQQPPPPPPQQPQPPPPQPQPAPQPPPPQQQP 1679
Query: 90 QLQSQPVHPGLLHSSPTAFRAPPSS 114
Q Q QP P P + PP S
Sbjct: 1680 QQQPQP-QPQQPPPPPPPQQQPPLS 1703
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 58.2 bits (139), Expect = 3e-08
Identities = 76/258 (29%), Positives = 105/258 (40%), Gaps = 44/258 (17%)
Query: 29 EQQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQQQQ-QQQQPPHPLS- 86
+Q QQQQQ QQQQ QQ LQ Q QLQQQQQQQQQQ QQQQ +
Sbjct: 3918 QQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGL 3977
Query: 87 ----------QLAQLQSQPVHPGLLHSSPTAFRAPPSSNSTAILHPSSRQGSQLNLNDHL 136
Q Q Q + PG+ F +P + T +L G + N D
Sbjct: 3978 LNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLL-----TGKEQNTVDPA 4032
Query: 137 LGHSPSSTATSGPGGGSRHRQASPLVHRRDSNPFTEIAMSSCKYSGGVMKPLSRLSASRR 196
+ SS AT GP S H Q PL S G +KP S S+
Sbjct: 4033 V----SSEATEGP---STH-QGGPLA--------IGTTPESMATEPGEVKP-SLSGDSQL 4075
Query: 197 NLIEAETEGQP--LQLFSPSNPPEIVISSREDNHAHQTLLHHP-NATHNHQHAGTTASST 253
L++ + + QP LQL P P +LLH +H +G+++ ++
Sbjct: 4076 LLVQPQPQPQPSSLQLQPPLRLP-------GQQQQQVSLLHTAGGGSHGQLGSGSSSEAS 4128
Query: 254 TFPKANKRKNQNIGYKLG 271
+ P + + ++G + G
Sbjct: 4129 SVPHLLAQPSVSLGDQPG 4146
Score = 47.8 bits (112), Expect = 4e-05
Identities = 57/166 (34%), Positives = 66/166 (39%), Gaps = 37/166 (22%)
Query: 35 QQQQQQQPPPPAPPAAPQ----------QPLGPS---LQPQPPQLQQQQQQ------QQQ 75
QQQQQQ A P + LGP LQ + QLQQQ+ Q QQQ
Sbjct: 3679 QQQQQQHSGGAGSLAGPSGGFFPGNLALRSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQ 3738
Query: 76 QQQQQPPHPLSQLAQLQSQPVHPGL-----LHSSPTAFRAPPSSNSTAI---LHPSSRQG 127
QQQQQ H L Q+A Q Q PG+ L P PPSS+ + L P QG
Sbjct: 3739 QQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKPQGL-MPPSSHQGLLVQQLSPQPPQG 3797
Query: 128 SQLNLNDH----LLGHSPSSTATSGPGGGSRHRQASPLVHRRDSNP 169
Q L L P + GP HRQ R S+P
Sbjct: 3798 PQGMLGPAQVAVLQQQHPGALGPQGP-----HRQVLMTQSRVLSSP 3838
Score = 47.4 bits (111), Expect = 5e-05
Identities = 36/80 (45%), Positives = 39/80 (48%), Gaps = 15/80 (18%)
Query: 26 SGDEQQQQQQQQQQ---------QQP--PPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQQ 74
+ +QQQQQQ QQQ QQ P QP+G Q Q Q QQQQQ Q
Sbjct: 3854 TAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQ 3913
Query: 75 QQQQQQPPHPLSQLAQLQSQ 94
QQQQQQ L Q QLQ Q
Sbjct: 3914 QQQQQQ----LQQQQQLQQQ 3929
Score = 46.6 bits (109), Expect = 8e-05
Identities = 35/84 (41%), Positives = 36/84 (42%), Gaps = 18/84 (21%)
Query: 29 EQQQQQQQQQQQ------------------QPPPPAPPAAPQQPLGPSLQPQPPQLQQQQ 70
+QQQQQQQ QQQ QP A P Q L Q Q Q QQQ
Sbjct: 3856 QQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQ 3915
Query: 71 QQQQQQQQQQPPHPLSQLAQLQSQ 94
QQQQ QQQQQ Q Q Q Q
Sbjct: 3916 QQQQLQQQQQLQQQQLQQQQQQQQ 3939
Score = 42.4 bits (98), Expect = 0.002
Identities = 34/86 (39%), Positives = 37/86 (43%), Gaps = 15/86 (17%)
Query: 29 EQQQQQQQQQQ--------QQPPPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQQQQQQQQ 80
+QQQQQQQQQQ QQ P Q LGP Q P Q QQ Q
Sbjct: 3735 QQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQP 3794
Query: 81 PPHPL-----SQLAQLQSQPVHPGLL 101
P P +Q+A LQ Q HPG L
Sbjct: 3795 PQGPQGMLGPAQVAVLQQQ--HPGAL 3818
Score = 41.2 bits (95), Expect = 0.003
Identities = 33/100 (33%), Positives = 41/100 (41%), Gaps = 8/100 (8%)
Query: 22 PCPSSGDEQQQQQQQQQQQQPPPPAPPAAPQQP--LGPSLQPQPPQLQQQQQQQQQQQQQ 79
P P +G Q+ + Q P PAPP A LGP + P PP Q+ ++
Sbjct: 4267 PGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGP-VHPTPPP----SSPQEPKRPS 4321
Query: 80 QPPHPLSQL-AQLQSQPVHPGLLHSSPTAFRAPPSSNSTA 118
Q P P SQL + Q P HPG PP S A
Sbjct: 4322 QLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPA 4361
Score = 36.2 bits (82), Expect = 0.11
Identities = 37/124 (29%), Positives = 45/124 (36%), Gaps = 8/124 (6%)
Query: 26 SGDEQQQQQQQQQQQQ------PPPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQQQQQQQ 79
S Q QQQQQQQQQ P P + P + PSL QL +Q
Sbjct: 3267 SAQLQPAQQQQQQQQQHSLLSAPGPAQAMSLPHEGSSPSLAGSQQQLSLGLAGARQPGLP 3326
Query: 80 QPPHPLSQLAQLQSQPVHPGLLHSSPTAFRAPPSSNSTAILHPSSRQGSQLNLNDHLLGH 139
QP P A Q + P + S A L P +Q SQ L+ +G
Sbjct: 3327 QPLMPTQPPAHALQQRLAPSMAMVSNQGHMLSGQHGGQAGLVP--QQSSQPVLSQKPMGT 3384
Query: 140 SPSS 143
P S
Sbjct: 3385 MPPS 3388
Score = 34.7 bits (78), Expect = 0.32
Identities = 23/52 (44%), Positives = 27/52 (51%), Gaps = 8/52 (15%)
Query: 29 EQQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQQQQQQQQ 80
EQQ + Q+Q Q QQ +L + QQQQQQQQQQQQQQ
Sbjct: 3569 EQQSKIQKQLDQ--------VRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQ 3612
Score = 34.3 bits (77), Expect = 0.42
Identities = 26/69 (37%), Positives = 34/69 (49%), Gaps = 10/69 (14%)
Query: 41 QPPPPAPPAA----PQQPLGPSLQ-----PQPPQLQQQQQQQQQQQQQQPPHPLSQLAQL 91
+PPPPA P++ +Q +G S P P L QQQQQQ QQQQ S +
Sbjct: 2774 RPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAM 2833
Query: 92 QSQ-PVHPG 99
++ P PG
Sbjct: 2834 SARFPSTPG 2842
Score = 33.9 bits (76), Expect = 0.55
Identities = 29/114 (25%), Positives = 40/114 (35%), Gaps = 16/114 (14%)
Query: 16 DEDPKCPCPSSGDEQQQQQQQQQQQQPPPPAPPAAPQQPL------GPSLQPQPPQLQQQ 69
+E P P Q ++ QP P A P++P GP L PQP +L
Sbjct: 748 EEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLS 807
Query: 70 QQQQQQQQQQQPPHPL-------SQLAQLQSQPV---HPGLLHSSPTAFRAPPS 113
Q ++ P P S L+ +P P H SP + P S
Sbjct: 808 PQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLS 861
Score = 32.3 bits (72), Expect = 1.6
Identities = 35/126 (27%), Positives = 42/126 (33%), Gaps = 39/126 (30%)
Query: 24 PSSGDEQQQQQQQQQQQQPPPPA------PPAAP-------------QQPLGPSLQPQPP 64
P + + Q + Q PPPA PP+ P Q PL P QP PP
Sbjct: 2333 PRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPP 2392
Query: 65 Q-----------------LQQQQQQQQQQQQQQPPHPLSQLAQLQSQPVHPGLLHSSPTA 107
+ + Q Q Q P PLS A S PV P SP
Sbjct: 2393 ESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPS-PVTPRF--QSPDP 2449
Query: 108 FRAPPS 113
+ PPS
Sbjct: 2450 YSRPPS 2455
Score = 32.0 bits (71), Expect = 2.1
Identities = 20/39 (51%), Positives = 23/39 (58%), Gaps = 4/39 (10%)
Query: 67 QQQQQQQQQQQQQQPPHPLSQLAQLQSQPVHPGLLHSSP 105
+QQQQQQQQQQQQQ + L+ QS P LL P
Sbjct: 3598 KQQQQQQQQQQQQQQHSAVLALSPSQS----PRLLTKLP 3632
Score = 30.8 bits (68), Expect = 4.7
Identities = 32/116 (27%), Positives = 42/116 (36%), Gaps = 19/116 (16%)
Query: 16 DEDPKCPCPSSGDEQQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQPQP--PQLQQQQQQQ 73
++ P P P D ++ P P P P+ GP L P+P P L + ++
Sbjct: 703 EDSPASPPPE--DSLMSLPLEESPLLPLPEEPQLCPRSE-GPHLSPRPEEPHLSPRPEEP 759
Query: 74 QQQQQQQPPHPLSQLAQLQSQPVHPGLL------HSSPTAFRAPPSSNSTAILHPS 123
Q + PH L QP P L H SP A P S LH S
Sbjct: 760 HLSPQAEEPH-------LSPQPEEPCLCAVPEEPHLSPQA-EGPHLSPQPEELHLS 807
Score = 30.4 bits (67), Expect = 6.1
Identities = 31/145 (21%), Positives = 45/145 (31%), Gaps = 15/145 (10%)
Query: 16 DEDPKCPCPSSGDEQQQQQQQQQQQQPPP------PAPPAAPQQPLGPSLQPQPPQLQQQ 69
+E P P P + ++ PPP P P P PL +L P +
Sbjct: 436 EEMPLLPPPE--ESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESP 493
Query: 70 QQQQQQQQQQQPPHPLSQLAQLQSQPVHPGLLHSSPTAFRAPPSSNSTAILHPSSRQGSQ 129
++ PP S + L+ P+ SP P + T + P
Sbjct: 494 LSPPPEESPLSPPPESSPFSPLEESPL-------SPPEESPPSPALETPLSPPPEASPLS 546
Query: 130 LNLNDHLLGHSPSSTATSGPGGGSR 154
+ L P TS P SR
Sbjct: 547 PPFEESPLSPPPEELPTSPPPEASR 571
Score = 30.4 bits (67), Expect = 6.1
Identities = 24/96 (25%), Positives = 35/96 (36%), Gaps = 20/96 (20%)
Query: 16 DEDPKCPCPSSGDEQQQQQQQQQQQQPPPPAPPA----APQQPLGPS----LQPQPPQLQ 67
D DP+ P + E + P P PP +P P+GP+ ++P PPQ
Sbjct: 966 DSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCS 1025
Query: 68 QQQQQQQQQQQQQP------------PHPLSQLAQL 91
Q Q P P PLS + ++
Sbjct: 1026 PLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKV 1061
Score = 30.0 bits (66), Expect = 8.0
Identities = 30/118 (25%), Positives = 42/118 (35%), Gaps = 5/118 (4%)
Query: 52 QQPLGPSLQPQPPQLQQQQQQQQQQQQQQPPHPLSQLAQLQSQPVHPGLLHSSPTAFRAP 111
+Q L LQP QQQQQQQQQ P P +Q L + P L S
Sbjct: 3263 KQQLSAQLQPA----QQQQQQQQQHSLLSAPGP-AQAMSLPHEGSSPSLAGSQQQLSLGL 3317
Query: 112 PSSNSTAILHPSSRQGSQLNLNDHLLGHSPSSTATSGPGGGSRHRQASPLVHRRDSNP 169
+ + P + L S + + G +H + LV ++ S P
Sbjct: 3318 AGARQPGLPQPLMPTQPPAHALQQRLAPSMAMVSNQGHMLSGQHGGQAGLVPQQSSQP 3375
>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
tract binding protein associated) [Homo sapiens]
Length = 707
Score = 58.2 bits (139), Expect = 3e-08
Identities = 48/141 (34%), Positives = 56/141 (39%), Gaps = 25/141 (17%)
Query: 11 GVGDLDEDPKCPCPSSGDEQQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQQ 70
G G PK P P QQQQQPPP PP PQQP P QP P
Sbjct: 48 GPGPGQSGPKPPIPPP-------PPHQQQQQPPPQQPP--PQQP--PPHQPPP-----HP 91
Query: 71 QQQQQQQQQQPPHPLSQLAQLQSQPVHPGLLHSSPTAFRAPPSSNSTAILHPSSRQGSQL 130
Q QQQQ PP S+ Q PG+ + P + APP++ T+ P S G
Sbjct: 92 QPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPT- 150
Query: 131 NLNDHLLGHSPSSTATSGPGG 151
+P TS P G
Sbjct: 151 --------PTPPPAVTSAPPG 163
>gi|4507379 TATA box binding protein [Homo sapiens]
Length = 339
Score = 56.6 bits (135), Expect = 8e-08
Identities = 40/99 (40%), Positives = 49/99 (49%), Gaps = 14/99 (14%)
Query: 29 EQQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQQQQQQQQPPHPLSQL 88
E+QQ+QQQQQQQQ QQ Q Q Q QQQQQQQQQQQQQQ + +
Sbjct: 53 EEQQRQQQQQQQQ----------QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAV 102
Query: 89 AQLQSQPVHPGLLHSSPTAFRAPPSSNS----TAILHPS 123
Q SQ G +P F + + + T L+PS
Sbjct: 103 QQSTSQQATQGTSGQAPQLFHSQTLTTAPLPGTTPLYPS 141
Score = 53.5 bits (127), Expect = 7e-07
Identities = 47/146 (32%), Positives = 53/146 (36%), Gaps = 21/146 (14%)
Query: 44 PPAPPAAPQQPLGPSLQPQP------------PQLQQQQQQQQQQQQQQPPHPLSQLAQL 91
P P +P P G L PQP Q QQQQQQQQQQQQQQ Q Q
Sbjct: 23 PGIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQ 82
Query: 92 QSQPVHPGLLHSSPTAFRAPPSSNSTAILHPSSRQGSQLNLNDHLLGHSPSSTATSGPGG 151
Q Q A A S S +S Q QL S T T+ P
Sbjct: 83 QQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQL---------FHSQTLTTAPLP 133
Query: 152 GSRHRQASPLVHRRDSNPFTEIAMSS 177
G+ SP+ P T + SS
Sbjct: 134 GTTPLYPSPMTPMTPITPATPASESS 159
Score = 37.0 bits (84), Expect = 0.065
Identities = 33/104 (31%), Positives = 42/104 (40%), Gaps = 5/104 (4%)
Query: 29 EQQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQQQQQQQQPPHPLSQL 88
+QQQQQQQQQQQQ A + S Q Q Q Q Q PL
Sbjct: 76 QQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQLFHSQTLTTAPLPGT 135
Query: 89 AQLQSQPVHPGLLHSSPTAFRAPPSSNSTAILHPSSRQGSQLNL 132
L P+ P + +P A P+S S+ I+ S +NL
Sbjct: 136 TPLYPSPMTP-MTPITP----ATPASESSGIVPQLQNIVSTVNL 174
>gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]
Length = 2063
Score = 56.6 bits (135), Expect = 8e-08
Identities = 59/203 (29%), Positives = 74/203 (36%), Gaps = 26/203 (12%)
Query: 24 PSSGDEQQQQQQ---QQQQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQQQQQQQQ 80
PS EQ+ QQ Q Q PPP PP QP P Q PP Q Q QQQQQQQQQ
Sbjct: 974 PSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQM 1033
Query: 81 PPHPLSQLAQLQSQPVHPGLLHSSPTAFRAPPSSNSTAILHPSSRQGSQLNLNDHLLGHS 140
+ L ++ P + R P S N P + ++ + G
Sbjct: 1034 ----MMML-----------MMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQS--GSV 1076
Query: 141 PSSTATSGPGGGSRHRQASPLVHRRDSNPFTEIAMSSCK--YSGGVMKPLSRLSASRRNL 198
P + GP SP R T + +S K Y P S A +L
Sbjct: 1077 PVMVSLQGPAS----VPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASL 1132
Query: 199 IEAETEGQPLQLFSPSNPPEIVI 221
EA P P+N P V+
Sbjct: 1133 PEASGSEAPSVPGGPNNMPSHVV 1155
Score = 53.5 bits (127), Expect = 7e-07
Identities = 43/130 (33%), Positives = 51/130 (39%), Gaps = 20/130 (15%)
Query: 19 PKCPCPSSGDEQQQQ-----QQQQQQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQ 73
P+ P P+S + QQQ APP P QP+ + Q P Q QQQQ
Sbjct: 205 PRTPRPASQSDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPVSVNRQMNPANFPQLQQQQ 264
Query: 74 QQQQQQQPPHPLSQLAQLQSQ-PVHPGLLH------------SSPTAFRAPPSSNS--TA 118
QQQQQQQ Q Q Q Q P H ++PT PP N +
Sbjct: 265 QQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWNQLPSG 324
Query: 119 ILHPSSRQGS 128
L P QGS
Sbjct: 325 ALQPPPAQGS 334
Score = 42.7 bits (99), Expect = 0.001
Identities = 57/227 (25%), Positives = 77/227 (33%), Gaps = 33/227 (14%)
Query: 22 PCPSSGDEQQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQQQQQQQQP 81
P P +Q Q Q QQQQ PPP P + QQ QQQQQ QQ
Sbjct: 996 PPPQPPQQQPQPQLPQQQQPPPPSQPQSQQQQ-------------QQQQQMMMMLMMQQD 1042
Query: 82 PHPLSQLAQLQSQPVHPGLLHSSPTAFRAP-PSSNSTAILHPSSRQGSQLNLNDHLLGHS 140
P + SQ VHP +P + R P S S ++ S D
Sbjct: 1043 P---KSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPM 1099
Query: 141 PSSTATSGPGGGSRHRQASPLVHRRDSNPFTEIA-------MSSCKYSGGVMKPLSRLSA 193
P +T G SR S+P E+A + GG S +
Sbjct: 1100 PVNTPL---GSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEAPSVPGGPNNMPSHVVL 1156
Query: 194 SRRNLIEA--ETEGQPLQLFSPSNPPEIVISSREDNHAHQTLLHHPN 238
+ L+ + PL + P + ++S +H H H PN
Sbjct: 1157 PQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGH----HFPN 1199
Score = 40.0 bits (92), Expect = 0.008
Identities = 40/140 (28%), Positives = 55/140 (39%), Gaps = 5/140 (3%)
Query: 15 LDEDPKCPCPSSGDEQQQQQQQQQQQQP-PPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQ 73
L + + P PS QQQQQQQQQ P + + P+ ++ P L Q+
Sbjct: 1009 LPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRM 1068
Query: 74 QQQQQQQPPHPLSQLAQLQSQPVHPGLLHSSPTAFRAPPSSNSTAILHPSSRQGSQLNLN 133
QQ P +S L S P P P P SNS +++ S Q +
Sbjct: 1069 PMQQSGSVPVMVS-LQGPASVPPSPD-KQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPL 1126
Query: 134 DHL--LGHSPSSTATSGPGG 151
+ L + S A S PGG
Sbjct: 1127 AEMASLPEASGSEAPSVPGG 1146
Score = 35.0 bits (79), Expect = 0.25
Identities = 39/127 (30%), Positives = 50/127 (39%), Gaps = 24/127 (18%)
Query: 35 QQQQQQQPPPPAPPAAPQQPLGPSLQP-QPPQLQQQQQQQQ-QQQQQQPPHPLSQLAQLQ 92
Q QQQ P PP PQ P P + P +QQ QQQPP+
Sbjct: 448 QTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQPPNQ-------G 500
Query: 93 SQPVHPGLLHSSPTAFRAPPSSNSTAILHPSSRQGSQLNLNDHLLGHSPSSTATSGPGGG 152
Q +HPGL R PP ++ Q N N + G PS+TAT+ G
Sbjct: 501 PQSLHPGL---GGMPKRLPPGFSA-----------GQANPN-FMQGQVPSTTATTPGNSG 545
Query: 153 SRHRQAS 159
+ QA+
Sbjct: 546 APQLQAN 552
Score = 34.3 bits (77), Expect = 0.42
Identities = 46/163 (28%), Positives = 61/163 (37%), Gaps = 26/163 (15%)
Query: 24 PSSGDEQQQQQQQQQQQQPPP--PAPPAAPQQPLGPSLQPQPPQLQQQQQQQQQQQQQQP 81
P +QQQ Q + Q P P PP Q P G +LQP P Q Q ++ P
Sbjct: 290 PPQQHQQQQPQGIRPQFTAPTQVPVPPGWNQLPSG-ALQPPPAQGSLGTMTANQGWKKAP 348
Query: 82 -PHPLSQLAQLQ------SQPVHP------GLLHSSPTAFRAPPSSNSTAILHP--SSRQ 126
P P+ Q Q + P HP G +S P SN P S Q
Sbjct: 349 LPGPMQQQLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQ 408
Query: 127 GSQLNL-----NDHLLGHSPSSTATSGPGGGSRHRQASPLVHR 164
G + HL SP+S+ +S G +SP V++
Sbjct: 409 GGPSRVPTPLQQPHLTNKSPASSPSSFQQGSP---ASSPTVNQ 448
>gi|187829452 autism susceptibility candidate 2 isoform 2 [Homo
sapiens]
Length = 1235
Score = 55.5 bits (132), Expect = 2e-07
Identities = 74/268 (27%), Positives = 97/268 (36%), Gaps = 43/268 (16%)
Query: 20 KCPCPSSGDEQQQQQQQQQQQQPPPPAP----PAAPQQPLGPSLQPQPPQ--LQQQQQQQ 73
K PCP Q Q + Q + P P AP QP P L QPPQ + Q Q
Sbjct: 296 KDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQP--PPLSTQPPQGPPEAQLQPA 353
Query: 74 QQQQQQQPPHPLSQLAQLQSQPVHPGLLHSSPTAFRAPPSSNSTAILH-----------P 122
Q Q Q+PP P S QL Q + P H S + P S+ +++ L P
Sbjct: 354 PQPQVQRPPRPQSP-TQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTP 412
Query: 123 SSRQGSQLNLNDH---------LLGHSP--SSTATSGPGGGSRH-RQASPLVHRRDSNPF 170
+ Q + +++ H L HSP S T T P S H +P P
Sbjct: 413 AKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPPL 472
Query: 171 TEIAMSSCKYSGGVMKPLSRLSASRRNLIEAETEGQPLQLFSPSNPPEIVISSREDNHAH 230
T ++ + G S R+ L Q + PP + R + H H
Sbjct: 473 TSGSLQVAGHPAG--STYSEQDILRQELNTRFLASQSADRGASLGPPPYL---RTEFHQH 527
Query: 231 QTLLHHPNATHNHQHAGTTASSTTFPKA 258
Q H TH H H T T FP A
Sbjct: 528 Q---HQHQHTHQHTHQHT---FTPFPHA 549
>gi|17864090 autism susceptibility candidate 2 isoform 1 [Homo
sapiens]
Length = 1259
Score = 55.5 bits (132), Expect = 2e-07
Identities = 74/268 (27%), Positives = 97/268 (36%), Gaps = 43/268 (16%)
Query: 20 KCPCPSSGDEQQQQQQQQQQQQPPPPAP----PAAPQQPLGPSLQPQPPQ--LQQQQQQQ 73
K PCP Q Q + Q + P P AP QP P L QPPQ + Q Q
Sbjct: 296 KDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQP--PPLSTQPPQGPPEAQLQPA 353
Query: 74 QQQQQQQPPHPLSQLAQLQSQPVHPGLLHSSPTAFRAPPSSNSTAILH-----------P 122
Q Q Q+PP P S QL Q + P H S + P S+ +++ L P
Sbjct: 354 PQPQVQRPPRPQSP-TQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTP 412
Query: 123 SSRQGSQLNLNDH---------LLGHSP--SSTATSGPGGGSRH-RQASPLVHRRDSNPF 170
+ Q + +++ H L HSP S T T P S H +P P
Sbjct: 413 AKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPPL 472
Query: 171 TEIAMSSCKYSGGVMKPLSRLSASRRNLIEAETEGQPLQLFSPSNPPEIVISSREDNHAH 230
T ++ + G S R+ L Q + PP + R + H H
Sbjct: 473 TSGSLQVAGHPAG--STYSEQDILRQELNTRFLASQSADRGASLGPPPYL---RTEFHQH 527
Query: 231 QTLLHHPNATHNHQHAGTTASSTTFPKA 258
Q H TH H H T T FP A
Sbjct: 528 Q---HQHQHTHQHTHQHT---FTPFPHA 549
>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
Length = 788
Score = 55.5 bits (132), Expect = 2e-07
Identities = 39/81 (48%), Positives = 44/81 (54%), Gaps = 15/81 (18%)
Query: 29 EQQQQQQQQQQQ------QPPPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQQQQ---QQQ 79
+QQQQQQQQQQQ QPP PP QQP P Q P QLQQ Q Q Q Q
Sbjct: 249 QQQQQQQQQQQQQQALQAQPPIQQPPM--QQPQPPPSQALPQQLQQMHHTQHHQPPPQPQ 306
Query: 80 QPPHPLSQLAQL----QSQPV 96
QPP +Q +QL Q+QP+
Sbjct: 307 QPPVAQNQPSQLPPQSQTQPL 327
Score = 55.1 bits (131), Expect = 2e-07
Identities = 34/69 (49%), Positives = 35/69 (50%), Gaps = 3/69 (4%)
Query: 30 QQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQPQPP---QLQQQQQQQQQQQQQQPPHPLS 86
QQQQQQQQQQQQ A A P P QPQPP L QQ QQ Q QPP
Sbjct: 247 QQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQ 306
Query: 87 QLAQLQSQP 95
Q Q+QP
Sbjct: 307 QPPVAQNQP 315
Score = 53.9 bits (128), Expect = 5e-07
Identities = 46/118 (38%), Positives = 52/118 (44%), Gaps = 21/118 (17%)
Query: 29 EQQQQQQQQQQQQP------PPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQQQQQQQ--- 79
+QQQ QQQQQQQQ QQ L Q Q Q QQQQQQQQQQQQQ
Sbjct: 206 QQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQ 265
Query: 80 -----------QPPHPLSQLAQLQSQPVHPGLLHSSPTAFRAPP-SSNSTAILHPSSR 125
QP P SQ Q Q +H H P + PP + N + L P S+
Sbjct: 266 AQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQ 323
Score = 48.9 bits (115), Expect = 2e-05
Identities = 52/161 (32%), Positives = 61/161 (37%), Gaps = 30/161 (18%)
Query: 29 EQQQQQQ-------------QQQQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQQ- 74
+QQQQQQ QQQQQQ A +A QQ +Q Q QLQQQQQQQQ
Sbjct: 161 QQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQ-QQQQLQQQQQQQQH 219
Query: 75 --------QQQQQQPPHPLSQLAQL---QSQPVHPGLLHSSPTAFRAPPSSNSTAILH-- 121
QQQ QQ L ++AQL Q Q A +A P +
Sbjct: 220 LIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQ 279
Query: 122 --PSSRQGSQLNLNDHLLGHSPSSTATSGPGGGSRHRQASP 160
PS QL H H P P ++ Q P
Sbjct: 280 PPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPP 320
Score = 45.4 bits (106), Expect = 2e-04
Identities = 48/206 (23%), Positives = 77/206 (37%), Gaps = 25/206 (12%)
Query: 29 EQQQQQQQQ-------------QQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQQQ 75
+QQQQQQQQ QQ QPPP Q + + QPP QQ Q
Sbjct: 254 QQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQN 313
Query: 76 QQQQQPPHPLSQLAQLQSQPVHPGLLHSSPTA--FRAPPSSNSTAILHPSSRQGSQLNLN 133
Q Q PP +Q Q+Q + +L++ P RAP + +Q + +
Sbjct: 314 QPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTA 373
Query: 134 D--HLLGHSPSSTATSGPGGGSRHRQASPLVHRRDSNPFTEIAMSSCKYSGGVMKPLSRL 191
++ + GG R P + P + I + +P++++
Sbjct: 374 QAAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLG--------RQPMAQV 425
Query: 192 SASRRNLIEAETEGQPLQLFSPSNPP 217
S S ++ + + GQ +Q PP
Sbjct: 426 SQSSLPMLSSPSPGQQVQTPQSMPPP 451
Score = 41.6 bits (96), Expect = 0.003
Identities = 39/135 (28%), Positives = 51/135 (37%), Gaps = 15/135 (11%)
Query: 22 PCPSSGDEQQQQQQQQQQQQPPPPAP---PAAPQQP--LGPSLQPQPPQLQQQQQQQQQQ 76
P PS QQ QQ Q PPP P P A QP L P Q Q P + Q Q Q
Sbjct: 280 PPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQ-PLVSQAQALPGQM 338
Query: 77 QQQQPPHPLSQLAQLQSQPVHPGLLHSSPTAFRAPPSSNSTA----ILHPSSRQGSQLNL 132
QPP + + QP + TA + ++ A ++ + QG
Sbjct: 339 LYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGM--- 395
Query: 133 NDHLLGHSPSSTATS 147
H+ P +TA S
Sbjct: 396 --HIRARFPPTTAVS 408
Score = 40.0 bits (92), Expect = 0.008
Identities = 33/92 (35%), Positives = 35/92 (38%), Gaps = 7/92 (7%)
Query: 10 SGVGDLDEDPKCPCPSSGDEQQQQQQQQQQQQPPPPAPPAAPQQPLGPS-------LQPQ 62
+G+G P G Q QPPP AP S LQ Q
Sbjct: 97 AGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQ 156
Query: 63 PPQLQQQQQQQQQQQQQQPPHPLSQLAQLQSQ 94
LQQQQQQQQ QQQQQ Q Q Q Q
Sbjct: 157 QVALQQQQQQQQFQQQQQAALQQQQQQQQQQQ 188
Score = 32.3 bits (72), Expect = 1.6
Identities = 29/107 (27%), Positives = 36/107 (33%), Gaps = 6/107 (5%)
Query: 24 PSSGDEQQQQQQQQQQQQPPP----PAPPAAPQQP--LGPSLQPQPPQLQQQQQQQQQQQ 77
PSS +Q Q Q P P+P Q P + P QP P Q Q
Sbjct: 411 PSSSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVS 470
Query: 78 QQQPPHPLSQLAQLQSQPVHPGLLHSSPTAFRAPPSSNSTAILHPSS 124
P P S L QP + +P F P ++PSS
Sbjct: 471 SGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSS 517
Score = 30.4 bits (67), Expect = 6.1
Identities = 29/85 (34%), Positives = 33/85 (38%), Gaps = 14/85 (16%)
Query: 42 PPPPAPPAAP-------QQPLGPSLQPQPPQLQQQ---QQQQQQQQQQQPPHPLSQLAQL 91
PP A A P +QP+ Q P L QQ Q Q PP P Q Q
Sbjct: 402 PPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQP 461
Query: 92 QSQP---VHPGLLHSSPTAFRAPPS 113
SQP V G SP++F PS
Sbjct: 462 SSQPNSNVSSGPA-PSPSSFLPSPS 485
>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
Length = 748
Score = 55.5 bits (132), Expect = 2e-07
Identities = 39/81 (48%), Positives = 44/81 (54%), Gaps = 15/81 (18%)
Query: 29 EQQQQQQQQQQQ------QPPPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQQQQ---QQQ 79
+QQQQQQQQQQQ QPP PP QQP P Q P QLQQ Q Q Q Q
Sbjct: 249 QQQQQQQQQQQQQQALQAQPPIQQPPM--QQPQPPPSQALPQQLQQMHHTQHHQPPPQPQ 306
Query: 80 QPPHPLSQLAQL----QSQPV 96
QPP +Q +QL Q+QP+
Sbjct: 307 QPPVAQNQPSQLPPQSQTQPL 327
Score = 55.1 bits (131), Expect = 2e-07
Identities = 34/69 (49%), Positives = 35/69 (50%), Gaps = 3/69 (4%)
Query: 30 QQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQPQPP---QLQQQQQQQQQQQQQQPPHPLS 86
QQQQQQQQQQQQ A A P P QPQPP L QQ QQ Q QPP
Sbjct: 247 QQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQ 306
Query: 87 QLAQLQSQP 95
Q Q+QP
Sbjct: 307 QPPVAQNQP 315
Score = 53.9 bits (128), Expect = 5e-07
Identities = 46/118 (38%), Positives = 52/118 (44%), Gaps = 21/118 (17%)
Query: 29 EQQQQQQQQQQQQP------PPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQQQQQQQ--- 79
+QQQ QQQQQQQQ QQ L Q Q Q QQQQQQQQQQQQQ
Sbjct: 206 QQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQ 265
Query: 80 -----------QPPHPLSQLAQLQSQPVHPGLLHSSPTAFRAPP-SSNSTAILHPSSR 125
QP P SQ Q Q +H H P + PP + N + L P S+
Sbjct: 266 AQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQ 323
Score = 48.9 bits (115), Expect = 2e-05
Identities = 52/161 (32%), Positives = 61/161 (37%), Gaps = 30/161 (18%)
Query: 29 EQQQQQQ-------------QQQQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQQ- 74
+QQQQQQ QQQQQQ A +A QQ +Q Q QLQQQQQQQQ
Sbjct: 161 QQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQ-QQQQLQQQQQQQQH 219
Query: 75 --------QQQQQQPPHPLSQLAQL---QSQPVHPGLLHSSPTAFRAPPSSNSTAILH-- 121
QQQ QQ L ++AQL Q Q A +A P +
Sbjct: 220 LIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQ 279
Query: 122 --PSSRQGSQLNLNDHLLGHSPSSTATSGPGGGSRHRQASP 160
PS QL H H P P ++ Q P
Sbjct: 280 PPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPP 320
Score = 44.7 bits (104), Expect = 3e-04
Identities = 63/223 (28%), Positives = 84/223 (37%), Gaps = 43/223 (19%)
Query: 29 EQQQQQQQQQQ-------------QQPPPPAPPAAPQQPLG--------PSLQPQ-PPQL 66
+QQQQQQQQQQ QQP PP A PQQ P QPQ PP
Sbjct: 252 QQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVA 311
Query: 67 QQQQQQQQQQQQQQPPHPLSQLAQLQSQPVH---PGLLHSSPTAFRAPP-----SSNSTA 118
Q Q Q Q Q QP +SQ L Q ++ P +P + PP TA
Sbjct: 312 QNQPSQLPPQSQTQP--LVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTA 369
Query: 119 ILHPSSRQ----GSQLNLNDHLLGHSPS-STATSGPGGGSRHRQASPLVHRRDSNPFTEI 173
+ + Q G Q++ + + SPS P Q SP + S P + +
Sbjct: 370 VQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNV 429
Query: 174 AMSSCKYSGGVMKPLSRLSASRRNLIEAETEGQPLQLFSPSNP 216
+ SG P S L + ++ + Q FS +P
Sbjct: 430 S------SGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSP 466
Score = 42.4 bits (98), Expect = 0.002
Identities = 49/189 (25%), Positives = 63/189 (33%), Gaps = 50/189 (26%)
Query: 22 PCPSSGDEQQQQQQQQQQQQPPPP---APPAAPQQP--LGPSLQPQP------------- 63
P PS QQ QQ Q PPP PP A QP L P Q QP
Sbjct: 280 PPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQML 339
Query: 64 -----------PQLQQQQQQQQQQQQQQPPHPLSQLAQLQSQPVH-------------PG 99
P + QQ Q Q QQQQ +Q AQ+ + V PG
Sbjct: 340 YTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPG 399
Query: 100 LLHSSPTAFRAPPSSNSTAILHPSSRQGSQLNLNDHLLGHSPSSTATSGPGGGSRHRQAS 159
+P + PP PS + G + + + P+ + +S S S
Sbjct: 400 QQVQTPQSMPPPP--------QPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQS 451
Query: 160 PLVHRRDSN 168
P+ R N
Sbjct: 452 PVTARTPQN 460
Score = 40.0 bits (92), Expect = 0.008
Identities = 33/92 (35%), Positives = 35/92 (38%), Gaps = 7/92 (7%)
Query: 10 SGVGDLDEDPKCPCPSSGDEQQQQQQQQQQQQPPPPAPPAAPQQPLGPS-------LQPQ 62
+G+G P G Q QPPP AP S LQ Q
Sbjct: 97 AGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQ 156
Query: 63 PPQLQQQQQQQQQQQQQQPPHPLSQLAQLQSQ 94
LQQQQQQQQ QQQQQ Q Q Q Q
Sbjct: 157 QVALQQQQQQQQFQQQQQAALQQQQQQQQQQQ 188
Score = 32.3 bits (72), Expect = 1.6
Identities = 23/94 (24%), Positives = 28/94 (29%)
Query: 31 QQQQQQQQQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQQQQQQQQPPHPLSQLAQ 90
Q Q P P Q + P QP P Q Q P P S L
Sbjct: 384 QVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPS 443
Query: 91 LQSQPVHPGLLHSSPTAFRAPPSSNSTAILHPSS 124
QP + +P F P ++PSS
Sbjct: 444 PSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSS 477
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.132 0.389
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,262,982
Number of Sequences: 37866
Number of extensions: 1512766
Number of successful extensions: 36868
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 589
Number of HSP's successfully gapped in prelim test: 752
Number of HSP's that attempted gapping in prelim test: 16311
Number of HSP's gapped (non-prelim): 9691
length of query: 731
length of database: 18,247,518
effective HSP length: 110
effective length of query: 621
effective length of database: 14,082,258
effective search space: 8745082218
effective search space used: 8745082218
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.