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Search of human proteins with 239744300
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239744300 PREDICTED: otogelin isoform 2 [Homo sapiens]
(2852 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239755545 PREDICTED: otogelin isoform 1 [Homo sapiens] 6020 0.0
gi|239744300 PREDICTED: otogelin isoform 2 [Homo sapiens] 6020 0.0
gi|239749989 PREDICTED: otogelin isoform 2 [Homo sapiens] 6016 0.0
gi|239755543 PREDICTED: otogelin isoform 2 [Homo sapiens] 6007 0.0
gi|239744298 PREDICTED: otogelin isoform 1 [Homo sapiens] 6007 0.0
gi|239749987 PREDICTED: otogelin isoform 1 [Homo sapiens] 6003 0.0
gi|239755901 PREDICTED: chromosome 12 open reading frame 64 [Hom... 1167 0.0
gi|239750386 PREDICTED: chromosome 12 open reading frame 64 [Hom... 1167 0.0
gi|239744688 PREDICTED: hypothetical protein LOC283310 [Homo sap... 1167 0.0
gi|89191868 von Willebrand factor preproprotein [Homo sapiens] 654 0.0
gi|116284392 mucin 2 precursor [Homo sapiens] 615 e-175
gi|169202626 PREDICTED: similar to mucin 5, partial [Homo sapiens] 612 e-174
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens] 574 e-163
gi|161019170 mucin 5AC [Homo sapiens] 570 e-162
gi|134031945 SCO-spondin [Homo sapiens] 546 e-155
gi|151301154 mucin 6, gastric [Homo sapiens] 512 e-144
gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo ... 476 e-133
gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo ... 476 e-133
gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens] 430 e-119
gi|239751787 PREDICTED: hypothetical protein XP_002348012 [Homo ... 310 2e-83
gi|154146262 Fc fragment of IgG binding protein [Homo sapiens] 308 4e-83
gi|239757282 PREDICTED: similar to Fc fragment of IgG binding pr... 297 9e-80
gi|239757286 PREDICTED: similar to Fc fragment of IgG binding pr... 280 1e-74
gi|239755776 PREDICTED: similar to Mucin-19 [Homo sapiens] 268 4e-71
gi|134268640 tectorin alpha precursor [Homo sapiens] 237 1e-61
gi|16554449 zonadhesin isoform 3 [Homo sapiens] 230 2e-59
gi|27881494 zonadhesin isoform 6 [Homo sapiens] 230 2e-59
gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens] 160 2e-38
gi|239757284 PREDICTED: similar to Fc fragment of IgG binding pr... 147 1e-34
gi|37693519 BMP-binding endothelial regulator precursor protein ... 145 4e-34
>gi|239755545 PREDICTED: otogelin isoform 1 [Homo sapiens]
Length = 2852
Score = 6020 bits (15618), Expect = 0.0
Identities = 2852/2852 (100%), Positives = 2852/2852 (100%)
Query: 1 MGDKATVVGGQQAEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECVHPAFCDCRRFNA 60
MGDKATVVGGQQAEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECVHPAFCDCRRFNA
Sbjct: 1 MGDKATVVGGQQAEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECVHPAFCDCRRFNA 60
Query: 61 TGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQV 120
TGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQV
Sbjct: 61 TGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQV 120
Query: 121 HNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIV 180
HNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIV
Sbjct: 121 HNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIV 180
Query: 181 RHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHS 240
RHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHS
Sbjct: 181 RHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHS 240
Query: 241 WQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTAS 300
WQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTAS
Sbjct: 241 WQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTAS 300
Query: 301 CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 360
CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC
Sbjct: 301 CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 360
Query: 361 CPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDC 420
CPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDC
Sbjct: 361 CPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDC 420
Query: 421 NTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTL 480
NTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTL
Sbjct: 421 NTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTL 480
Query: 481 QNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS 540
QNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS
Sbjct: 481 QNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS 540
Query: 541 SVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPEST 600
SVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPEST
Sbjct: 541 SVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPEST 600
Query: 601 PQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPY 660
PQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPY
Sbjct: 601 PQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPY 660
Query: 661 FEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPC 720
FEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPC
Sbjct: 661 FEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPC 720
Query: 721 GRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDY 780
GRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDY
Sbjct: 721 GRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDY 780
Query: 781 PPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLL 840
PPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLL
Sbjct: 781 PPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLL 840
Query: 841 NLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG 900
NLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG
Sbjct: 841 NLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG 900
Query: 901 SFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSS 960
SFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSS
Sbjct: 901 SFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSS 960
Query: 961 GMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLW 1020
GMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLW
Sbjct: 961 GMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLW 1020
Query: 1021 DQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTL 1080
DQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTL
Sbjct: 1021 DQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTL 1080
Query: 1081 DPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECF 1140
DPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECF
Sbjct: 1081 DPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECF 1140
Query: 1141 CASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVG 1200
CASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVG
Sbjct: 1141 CASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVG 1200
Query: 1201 DDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFLHVTANGSLELAK 1260
DDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFLHVTANGSLELAK
Sbjct: 1201 DDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFLHVTANGSLELAK 1260
Query: 1261 WQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTL 1320
WQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTL
Sbjct: 1261 WQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTL 1320
Query: 1321 FRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCPTPQVLDE 1380
FRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCPTPQVLDE
Sbjct: 1321 FRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCPTPQVLDE 1380
Query: 1381 VTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTP 1440
VTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTP
Sbjct: 1381 VTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTP 1440
Query: 1441 AAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAI 1500
AAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAI
Sbjct: 1441 AAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAI 1500
Query: 1501 PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVT 1560
PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVT
Sbjct: 1501 PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVT 1560
Query: 1561 VRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV 1620
VRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV
Sbjct: 1561 VRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV 1620
Query: 1621 PQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQ 1680
PQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQ
Sbjct: 1621 PQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQ 1680
Query: 1681 PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSG 1740
PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSG
Sbjct: 1681 PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSG 1740
Query: 1741 LPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHP 1800
LPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHP
Sbjct: 1741 LPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHP 1800
Query: 1801 PTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPT 1860
PTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPT
Sbjct: 1801 PTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPT 1860
Query: 1861 SMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLV 1920
SMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLV
Sbjct: 1861 SMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLV 1920
Query: 1921 LLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCV 1980
LLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCV
Sbjct: 1921 LLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCV 1980
Query: 1981 PIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCS 2040
PIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCS
Sbjct: 1981 PIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCS 2040
Query: 2041 IFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNM 2100
IFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNM
Sbjct: 2041 IFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNM 2100
Query: 2101 THLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLM 2160
THLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLM
Sbjct: 2101 THLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLM 2160
Query: 2161 IVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT 2220
IVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT
Sbjct: 2161 IVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT 2220
Query: 2221 RFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAM 2280
RFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAM
Sbjct: 2221 RFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAM 2280
Query: 2281 CHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCV 2340
CHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCV
Sbjct: 2281 CHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCV 2340
Query: 2341 CSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDL 2400
CSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDL
Sbjct: 2341 CSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDL 2400
Query: 2401 GCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDS 2460
GCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDS
Sbjct: 2401 GCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDS 2460
Query: 2461 CCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEA 2520
CCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEA
Sbjct: 2461 CCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEA 2520
Query: 2521 LTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVP 2580
LTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVP
Sbjct: 2521 LTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVP 2580
Query: 2581 RCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHT 2640
RCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHT
Sbjct: 2581 RCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHT 2640
Query: 2641 SRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTT 2700
SRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTT
Sbjct: 2641 SRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTT 2700
Query: 2701 SLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTC 2760
SLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTC
Sbjct: 2701 SLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTC 2760
Query: 2761 KEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVG 2820
KEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVG
Sbjct: 2761 KEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVG 2820
Query: 2821 LQRRSVQLFCATNATWVPYTVQEPTDCACQWS 2852
LQRRSVQLFCATNATWVPYTVQEPTDCACQWS
Sbjct: 2821 LQRRSVQLFCATNATWVPYTVQEPTDCACQWS 2852
>gi|239744300 PREDICTED: otogelin isoform 2 [Homo sapiens]
Length = 2852
Score = 6020 bits (15618), Expect = 0.0
Identities = 2852/2852 (100%), Positives = 2852/2852 (100%)
Query: 1 MGDKATVVGGQQAEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECVHPAFCDCRRFNA 60
MGDKATVVGGQQAEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECVHPAFCDCRRFNA
Sbjct: 1 MGDKATVVGGQQAEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECVHPAFCDCRRFNA 60
Query: 61 TGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQV 120
TGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQV
Sbjct: 61 TGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQV 120
Query: 121 HNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIV 180
HNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIV
Sbjct: 121 HNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIV 180
Query: 181 RHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHS 240
RHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHS
Sbjct: 181 RHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHS 240
Query: 241 WQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTAS 300
WQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTAS
Sbjct: 241 WQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTAS 300
Query: 301 CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 360
CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC
Sbjct: 301 CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 360
Query: 361 CPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDC 420
CPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDC
Sbjct: 361 CPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDC 420
Query: 421 NTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTL 480
NTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTL
Sbjct: 421 NTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTL 480
Query: 481 QNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS 540
QNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS
Sbjct: 481 QNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS 540
Query: 541 SVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPEST 600
SVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPEST
Sbjct: 541 SVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPEST 600
Query: 601 PQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPY 660
PQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPY
Sbjct: 601 PQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPY 660
Query: 661 FEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPC 720
FEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPC
Sbjct: 661 FEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPC 720
Query: 721 GRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDY 780
GRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDY
Sbjct: 721 GRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDY 780
Query: 781 PPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLL 840
PPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLL
Sbjct: 781 PPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLL 840
Query: 841 NLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG 900
NLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG
Sbjct: 841 NLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG 900
Query: 901 SFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSS 960
SFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSS
Sbjct: 901 SFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSS 960
Query: 961 GMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLW 1020
GMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLW
Sbjct: 961 GMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLW 1020
Query: 1021 DQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTL 1080
DQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTL
Sbjct: 1021 DQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTL 1080
Query: 1081 DPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECF 1140
DPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECF
Sbjct: 1081 DPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECF 1140
Query: 1141 CASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVG 1200
CASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVG
Sbjct: 1141 CASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVG 1200
Query: 1201 DDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFLHVTANGSLELAK 1260
DDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFLHVTANGSLELAK
Sbjct: 1201 DDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFLHVTANGSLELAK 1260
Query: 1261 WQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTL 1320
WQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTL
Sbjct: 1261 WQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTL 1320
Query: 1321 FRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCPTPQVLDE 1380
FRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCPTPQVLDE
Sbjct: 1321 FRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCPTPQVLDE 1380
Query: 1381 VTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTP 1440
VTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTP
Sbjct: 1381 VTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTP 1440
Query: 1441 AAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAI 1500
AAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAI
Sbjct: 1441 AAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAI 1500
Query: 1501 PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVT 1560
PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVT
Sbjct: 1501 PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVT 1560
Query: 1561 VRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV 1620
VRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV
Sbjct: 1561 VRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV 1620
Query: 1621 PQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQ 1680
PQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQ
Sbjct: 1621 PQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQ 1680
Query: 1681 PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSG 1740
PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSG
Sbjct: 1681 PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSG 1740
Query: 1741 LPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHP 1800
LPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHP
Sbjct: 1741 LPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHP 1800
Query: 1801 PTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPT 1860
PTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPT
Sbjct: 1801 PTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPT 1860
Query: 1861 SMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLV 1920
SMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLV
Sbjct: 1861 SMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLV 1920
Query: 1921 LLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCV 1980
LLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCV
Sbjct: 1921 LLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCV 1980
Query: 1981 PIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCS 2040
PIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCS
Sbjct: 1981 PIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCS 2040
Query: 2041 IFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNM 2100
IFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNM
Sbjct: 2041 IFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNM 2100
Query: 2101 THLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLM 2160
THLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLM
Sbjct: 2101 THLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLM 2160
Query: 2161 IVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT 2220
IVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT
Sbjct: 2161 IVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT 2220
Query: 2221 RFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAM 2280
RFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAM
Sbjct: 2221 RFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAM 2280
Query: 2281 CHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCV 2340
CHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCV
Sbjct: 2281 CHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCV 2340
Query: 2341 CSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDL 2400
CSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDL
Sbjct: 2341 CSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDL 2400
Query: 2401 GCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDS 2460
GCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDS
Sbjct: 2401 GCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDS 2460
Query: 2461 CCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEA 2520
CCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEA
Sbjct: 2461 CCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEA 2520
Query: 2521 LTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVP 2580
LTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVP
Sbjct: 2521 LTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVP 2580
Query: 2581 RCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHT 2640
RCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHT
Sbjct: 2581 RCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHT 2640
Query: 2641 SRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTT 2700
SRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTT
Sbjct: 2641 SRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTT 2700
Query: 2701 SLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTC 2760
SLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTC
Sbjct: 2701 SLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTC 2760
Query: 2761 KEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVG 2820
KEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVG
Sbjct: 2761 KEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVG 2820
Query: 2821 LQRRSVQLFCATNATWVPYTVQEPTDCACQWS 2852
LQRRSVQLFCATNATWVPYTVQEPTDCACQWS
Sbjct: 2821 LQRRSVQLFCATNATWVPYTVQEPTDCACQWS 2852
>gi|239749989 PREDICTED: otogelin isoform 2 [Homo sapiens]
Length = 2852
Score = 6016 bits (15608), Expect = 0.0
Identities = 2851/2852 (99%), Positives = 2851/2852 (99%)
Query: 1 MGDKATVVGGQQAEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECVHPAFCDCRRFNA 60
MGDKATVVGGQQAEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECVHPAFCDCRRFNA
Sbjct: 1 MGDKATVVGGQQAEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECVHPAFCDCRRFNA 60
Query: 61 TGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQV 120
TGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQV
Sbjct: 61 TGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQV 120
Query: 121 HNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIV 180
HNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIV
Sbjct: 121 HNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIV 180
Query: 181 RHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHS 240
RHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHS
Sbjct: 181 RHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHS 240
Query: 241 WQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTAS 300
WQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTAS
Sbjct: 241 WQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTAS 300
Query: 301 CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 360
CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC
Sbjct: 301 CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 360
Query: 361 CPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDC 420
CPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDC
Sbjct: 361 CPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDC 420
Query: 421 NTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTL 480
NTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTL
Sbjct: 421 NTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTL 480
Query: 481 QNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS 540
QNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS
Sbjct: 481 QNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS 540
Query: 541 SVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPEST 600
SVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPEST
Sbjct: 541 SVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPEST 600
Query: 601 PQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPY 660
PQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPY
Sbjct: 601 PQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPY 660
Query: 661 FEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPC 720
FEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPC
Sbjct: 661 FEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPC 720
Query: 721 GRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDY 780
GRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDY
Sbjct: 721 GRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDY 780
Query: 781 PPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLL 840
PPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLL
Sbjct: 781 PPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLL 840
Query: 841 NLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG 900
NLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG
Sbjct: 841 NLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG 900
Query: 901 SFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSS 960
SFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSS
Sbjct: 901 SFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSS 960
Query: 961 GMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLW 1020
GMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLW
Sbjct: 961 GMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLW 1020
Query: 1021 DQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTL 1080
DQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTL
Sbjct: 1021 DQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTL 1080
Query: 1081 DPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECF 1140
DPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECF
Sbjct: 1081 DPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECF 1140
Query: 1141 CASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVG 1200
CASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVG
Sbjct: 1141 CASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVG 1200
Query: 1201 DDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFLHVTANGSLELAK 1260
DDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFLHVTANGSLELAK
Sbjct: 1201 DDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFLHVTANGSLELAK 1260
Query: 1261 WQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTL 1320
WQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTL
Sbjct: 1261 WQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTL 1320
Query: 1321 FRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCPTPQVLDE 1380
FRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCPTPQVLDE
Sbjct: 1321 FRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCPTPQVLDE 1380
Query: 1381 VTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTP 1440
VTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTP
Sbjct: 1381 VTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTP 1440
Query: 1441 AAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAI 1500
AAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAI
Sbjct: 1441 AAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAI 1500
Query: 1501 PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVT 1560
PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVT
Sbjct: 1501 PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVT 1560
Query: 1561 VRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV 1620
VRGHGSLPVRTTP QPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV
Sbjct: 1561 VRGHGSLPVRTTPLQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV 1620
Query: 1621 PQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQ 1680
PQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQ
Sbjct: 1621 PQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQ 1680
Query: 1681 PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSG 1740
PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSG
Sbjct: 1681 PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSG 1740
Query: 1741 LPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHP 1800
LPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHP
Sbjct: 1741 LPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHP 1800
Query: 1801 PTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPT 1860
PTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPT
Sbjct: 1801 PTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPT 1860
Query: 1861 SMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLV 1920
SMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLV
Sbjct: 1861 SMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLV 1920
Query: 1921 LLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCV 1980
LLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCV
Sbjct: 1921 LLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCV 1980
Query: 1981 PIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCS 2040
PIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCS
Sbjct: 1981 PIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCS 2040
Query: 2041 IFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNM 2100
IFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNM
Sbjct: 2041 IFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNM 2100
Query: 2101 THLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLM 2160
THLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLM
Sbjct: 2101 THLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLM 2160
Query: 2161 IVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT 2220
IVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT
Sbjct: 2161 IVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT 2220
Query: 2221 RFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAM 2280
RFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAM
Sbjct: 2221 RFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAM 2280
Query: 2281 CHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCV 2340
CHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCV
Sbjct: 2281 CHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCV 2340
Query: 2341 CSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDL 2400
CSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDL
Sbjct: 2341 CSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDL 2400
Query: 2401 GCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDS 2460
GCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDS
Sbjct: 2401 GCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDS 2460
Query: 2461 CCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEA 2520
CCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEA
Sbjct: 2461 CCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEA 2520
Query: 2521 LTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVP 2580
LTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVP
Sbjct: 2521 LTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVP 2580
Query: 2581 RCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHT 2640
RCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHT
Sbjct: 2581 RCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHT 2640
Query: 2641 SRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTT 2700
SRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTT
Sbjct: 2641 SRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTT 2700
Query: 2701 SLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTC 2760
SLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTC
Sbjct: 2701 SLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTC 2760
Query: 2761 KEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVG 2820
KEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVG
Sbjct: 2761 KEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVG 2820
Query: 2821 LQRRSVQLFCATNATWVPYTVQEPTDCACQWS 2852
LQRRSVQLFCATNATWVPYTVQEPTDCACQWS
Sbjct: 2821 LQRRSVQLFCATNATWVPYTVQEPTDCACQWS 2852
>gi|239755543 PREDICTED: otogelin isoform 2 [Homo sapiens]
Length = 2924
Score = 6007 bits (15583), Expect = 0.0
Identities = 2848/2852 (99%), Positives = 2848/2852 (99%), Gaps = 1/2852 (0%)
Query: 1 MGDKATVVGGQQAEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECVHPAFCDCRRFNA 60
MGDKATVVGGQ AEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECVHPAFCDCRRFNA
Sbjct: 74 MGDKATVVGGQ-AEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECVHPAFCDCRRFNA 132
Query: 61 TGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQV 120
TGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQV
Sbjct: 133 TGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQV 192
Query: 121 HNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIV 180
HNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIV
Sbjct: 193 HNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIV 252
Query: 181 RHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHS 240
RHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHS
Sbjct: 253 RHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHS 312
Query: 241 WQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTAS 300
WQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTAS
Sbjct: 313 WQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTAS 372
Query: 301 CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 360
CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC
Sbjct: 373 CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 432
Query: 361 CPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDC 420
CPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDC
Sbjct: 433 CPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDC 492
Query: 421 NTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTL 480
NTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTL
Sbjct: 493 NTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTL 552
Query: 481 QNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS 540
QNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS
Sbjct: 553 QNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS 612
Query: 541 SVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPEST 600
SVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPEST
Sbjct: 613 SVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPEST 672
Query: 601 PQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPY 660
PQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPY
Sbjct: 673 PQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPY 732
Query: 661 FEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPC 720
FEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPC
Sbjct: 733 FEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPC 792
Query: 721 GRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDY 780
GRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDY
Sbjct: 793 GRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDY 852
Query: 781 PPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLL 840
PPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLL
Sbjct: 853 PPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLL 912
Query: 841 NLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG 900
NLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG
Sbjct: 913 NLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG 972
Query: 901 SFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSS 960
SFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSS
Sbjct: 973 SFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSS 1032
Query: 961 GMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLW 1020
GMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLW
Sbjct: 1033 GMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLW 1092
Query: 1021 DQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTL 1080
DQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTL
Sbjct: 1093 DQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTL 1152
Query: 1081 DPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECF 1140
DPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECF
Sbjct: 1153 DPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECF 1212
Query: 1141 CASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVG 1200
CASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVG
Sbjct: 1213 CASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVG 1272
Query: 1201 DDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFLHVTANGSLELAK 1260
DDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFLHVTANGSLELAK
Sbjct: 1273 DDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFLHVTANGSLELAK 1332
Query: 1261 WQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTL 1320
WQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTL
Sbjct: 1333 WQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTL 1392
Query: 1321 FRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCPTPQVLDE 1380
FRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPR CVPVCPTPQVLDE
Sbjct: 1393 FRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPRGRSCVPVCPTPQVLDE 1452
Query: 1381 VTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTP 1440
VTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTP
Sbjct: 1453 VTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTP 1512
Query: 1441 AAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAI 1500
AAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAI
Sbjct: 1513 AAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAI 1572
Query: 1501 PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVT 1560
PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVT
Sbjct: 1573 PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVT 1632
Query: 1561 VRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV 1620
VRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV
Sbjct: 1633 VRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV 1692
Query: 1621 PQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQ 1680
PQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQ
Sbjct: 1693 PQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQ 1752
Query: 1681 PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSG 1740
PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSG
Sbjct: 1753 PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSG 1812
Query: 1741 LPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHP 1800
LPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHP
Sbjct: 1813 LPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHP 1872
Query: 1801 PTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPT 1860
PTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPT
Sbjct: 1873 PTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPT 1932
Query: 1861 SMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLV 1920
SMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLV
Sbjct: 1933 SMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLV 1992
Query: 1921 LLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCV 1980
LLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCV
Sbjct: 1993 LLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCV 2052
Query: 1981 PIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCS 2040
PIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCS
Sbjct: 2053 PIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCS 2112
Query: 2041 IFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNM 2100
IFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNM
Sbjct: 2113 IFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNM 2172
Query: 2101 THLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLM 2160
THLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLM
Sbjct: 2173 THLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLM 2232
Query: 2161 IVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT 2220
IVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT
Sbjct: 2233 IVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT 2292
Query: 2221 RFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAM 2280
RFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAM
Sbjct: 2293 RFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAM 2352
Query: 2281 CHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCV 2340
CHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCV
Sbjct: 2353 CHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCV 2412
Query: 2341 CSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDL 2400
CSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDL
Sbjct: 2413 CSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDL 2472
Query: 2401 GCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDS 2460
GCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDS
Sbjct: 2473 GCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDS 2532
Query: 2461 CCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEA 2520
CCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEA
Sbjct: 2533 CCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEA 2592
Query: 2521 LTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVP 2580
LTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVP
Sbjct: 2593 LTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVP 2652
Query: 2581 RCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHT 2640
RCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHT
Sbjct: 2653 RCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHT 2712
Query: 2641 SRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTT 2700
SRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTT
Sbjct: 2713 SRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTT 2772
Query: 2701 SLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTC 2760
SLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTC
Sbjct: 2773 SLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTC 2832
Query: 2761 KEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVG 2820
KEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVG
Sbjct: 2833 KEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVG 2892
Query: 2821 LQRRSVQLFCATNATWVPYTVQEPTDCACQWS 2852
LQRRSVQLFCATNATWVPYTVQEPTDCACQWS
Sbjct: 2893 LQRRSVQLFCATNATWVPYTVQEPTDCACQWS 2924
>gi|239744298 PREDICTED: otogelin isoform 1 [Homo sapiens]
Length = 2924
Score = 6007 bits (15583), Expect = 0.0
Identities = 2848/2852 (99%), Positives = 2848/2852 (99%), Gaps = 1/2852 (0%)
Query: 1 MGDKATVVGGQQAEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECVHPAFCDCRRFNA 60
MGDKATVVGGQ AEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECVHPAFCDCRRFNA
Sbjct: 74 MGDKATVVGGQ-AEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECVHPAFCDCRRFNA 132
Query: 61 TGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQV 120
TGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQV
Sbjct: 133 TGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQV 192
Query: 121 HNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIV 180
HNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIV
Sbjct: 193 HNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIV 252
Query: 181 RHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHS 240
RHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHS
Sbjct: 253 RHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHS 312
Query: 241 WQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTAS 300
WQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTAS
Sbjct: 313 WQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTAS 372
Query: 301 CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 360
CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC
Sbjct: 373 CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 432
Query: 361 CPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDC 420
CPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDC
Sbjct: 433 CPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDC 492
Query: 421 NTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTL 480
NTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTL
Sbjct: 493 NTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTL 552
Query: 481 QNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS 540
QNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS
Sbjct: 553 QNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS 612
Query: 541 SVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPEST 600
SVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPEST
Sbjct: 613 SVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPEST 672
Query: 601 PQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPY 660
PQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPY
Sbjct: 673 PQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPY 732
Query: 661 FEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPC 720
FEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPC
Sbjct: 733 FEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPC 792
Query: 721 GRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDY 780
GRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDY
Sbjct: 793 GRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDY 852
Query: 781 PPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLL 840
PPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLL
Sbjct: 853 PPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLL 912
Query: 841 NLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG 900
NLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG
Sbjct: 913 NLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG 972
Query: 901 SFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSS 960
SFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSS
Sbjct: 973 SFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSS 1032
Query: 961 GMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLW 1020
GMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLW
Sbjct: 1033 GMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLW 1092
Query: 1021 DQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTL 1080
DQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTL
Sbjct: 1093 DQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTL 1152
Query: 1081 DPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECF 1140
DPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECF
Sbjct: 1153 DPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECF 1212
Query: 1141 CASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVG 1200
CASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVG
Sbjct: 1213 CASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVG 1272
Query: 1201 DDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFLHVTANGSLELAK 1260
DDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFLHVTANGSLELAK
Sbjct: 1273 DDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFLHVTANGSLELAK 1332
Query: 1261 WQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTL 1320
WQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTL
Sbjct: 1333 WQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTL 1392
Query: 1321 FRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCPTPQVLDE 1380
FRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPR CVPVCPTPQVLDE
Sbjct: 1393 FRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPRGRSCVPVCPTPQVLDE 1452
Query: 1381 VTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTP 1440
VTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTP
Sbjct: 1453 VTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTP 1512
Query: 1441 AAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAI 1500
AAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAI
Sbjct: 1513 AAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAI 1572
Query: 1501 PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVT 1560
PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVT
Sbjct: 1573 PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVT 1632
Query: 1561 VRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV 1620
VRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV
Sbjct: 1633 VRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV 1692
Query: 1621 PQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQ 1680
PQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQ
Sbjct: 1693 PQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQ 1752
Query: 1681 PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSG 1740
PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSG
Sbjct: 1753 PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSG 1812
Query: 1741 LPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHP 1800
LPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHP
Sbjct: 1813 LPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHP 1872
Query: 1801 PTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPT 1860
PTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPT
Sbjct: 1873 PTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPT 1932
Query: 1861 SMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLV 1920
SMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLV
Sbjct: 1933 SMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLV 1992
Query: 1921 LLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCV 1980
LLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCV
Sbjct: 1993 LLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCV 2052
Query: 1981 PIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCS 2040
PIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCS
Sbjct: 2053 PIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCS 2112
Query: 2041 IFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNM 2100
IFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNM
Sbjct: 2113 IFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNM 2172
Query: 2101 THLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLM 2160
THLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLM
Sbjct: 2173 THLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLM 2232
Query: 2161 IVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT 2220
IVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT
Sbjct: 2233 IVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT 2292
Query: 2221 RFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAM 2280
RFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAM
Sbjct: 2293 RFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAM 2352
Query: 2281 CHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCV 2340
CHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCV
Sbjct: 2353 CHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCV 2412
Query: 2341 CSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDL 2400
CSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDL
Sbjct: 2413 CSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDL 2472
Query: 2401 GCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDS 2460
GCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDS
Sbjct: 2473 GCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDS 2532
Query: 2461 CCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEA 2520
CCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEA
Sbjct: 2533 CCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEA 2592
Query: 2521 LTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVP 2580
LTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVP
Sbjct: 2593 LTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVP 2652
Query: 2581 RCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHT 2640
RCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHT
Sbjct: 2653 RCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHT 2712
Query: 2641 SRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTT 2700
SRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTT
Sbjct: 2713 SRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTT 2772
Query: 2701 SLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTC 2760
SLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTC
Sbjct: 2773 SLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTC 2832
Query: 2761 KEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVG 2820
KEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVG
Sbjct: 2833 KEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVG 2892
Query: 2821 LQRRSVQLFCATNATWVPYTVQEPTDCACQWS 2852
LQRRSVQLFCATNATWVPYTVQEPTDCACQWS
Sbjct: 2893 LQRRSVQLFCATNATWVPYTVQEPTDCACQWS 2924
>gi|239749987 PREDICTED: otogelin isoform 1 [Homo sapiens]
Length = 2924
Score = 6003 bits (15573), Expect = 0.0
Identities = 2847/2852 (99%), Positives = 2847/2852 (99%), Gaps = 1/2852 (0%)
Query: 1 MGDKATVVGGQQAEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECVHPAFCDCRRFNA 60
MGDKATVVGGQ AEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECVHPAFCDCRRFNA
Sbjct: 74 MGDKATVVGGQ-AEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECVHPAFCDCRRFNA 132
Query: 61 TGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQV 120
TGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQV
Sbjct: 133 TGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQV 192
Query: 121 HNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIV 180
HNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIV
Sbjct: 193 HNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIV 252
Query: 181 RHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHS 240
RHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHS
Sbjct: 253 RHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHS 312
Query: 241 WQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTAS 300
WQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTAS
Sbjct: 313 WQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTAS 372
Query: 301 CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 360
CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC
Sbjct: 373 CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 432
Query: 361 CPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDC 420
CPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDC
Sbjct: 433 CPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDC 492
Query: 421 NTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTL 480
NTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTL
Sbjct: 493 NTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTL 552
Query: 481 QNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS 540
QNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS
Sbjct: 553 QNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS 612
Query: 541 SVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPEST 600
SVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPEST
Sbjct: 613 SVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPEST 672
Query: 601 PQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPY 660
PQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPY
Sbjct: 673 PQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPY 732
Query: 661 FEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPC 720
FEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPC
Sbjct: 733 FEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPC 792
Query: 721 GRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDY 780
GRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDY
Sbjct: 793 GRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDY 852
Query: 781 PPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLL 840
PPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLL
Sbjct: 853 PPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLL 912
Query: 841 NLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG 900
NLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG
Sbjct: 913 NLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG 972
Query: 901 SFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSS 960
SFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSS
Sbjct: 973 SFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSS 1032
Query: 961 GMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLW 1020
GMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLW
Sbjct: 1033 GMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLW 1092
Query: 1021 DQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTL 1080
DQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTL
Sbjct: 1093 DQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTL 1152
Query: 1081 DPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECF 1140
DPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECF
Sbjct: 1153 DPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECF 1212
Query: 1141 CASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVG 1200
CASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVG
Sbjct: 1213 CASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVG 1272
Query: 1201 DDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFLHVTANGSLELAK 1260
DDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFLHVTANGSLELAK
Sbjct: 1273 DDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFLHVTANGSLELAK 1332
Query: 1261 WQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTL 1320
WQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTL
Sbjct: 1333 WQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTL 1392
Query: 1321 FRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCPTPQVLDE 1380
FRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPR CVPVCPTPQVLDE
Sbjct: 1393 FRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPRGRSCVPVCPTPQVLDE 1452
Query: 1381 VTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTP 1440
VTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTP
Sbjct: 1453 VTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTP 1512
Query: 1441 AAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAI 1500
AAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAI
Sbjct: 1513 AAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAI 1572
Query: 1501 PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVT 1560
PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVT
Sbjct: 1573 PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVT 1632
Query: 1561 VRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV 1620
VRGHGSLPVRTTP QPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV
Sbjct: 1633 VRGHGSLPVRTTPLQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV 1692
Query: 1621 PQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQ 1680
PQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQ
Sbjct: 1693 PQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQ 1752
Query: 1681 PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSG 1740
PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSG
Sbjct: 1753 PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSG 1812
Query: 1741 LPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHP 1800
LPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHP
Sbjct: 1813 LPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHP 1872
Query: 1801 PTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPT 1860
PTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPT
Sbjct: 1873 PTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPT 1932
Query: 1861 SMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLV 1920
SMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLV
Sbjct: 1933 SMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLV 1992
Query: 1921 LLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCV 1980
LLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCV
Sbjct: 1993 LLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCV 2052
Query: 1981 PIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCS 2040
PIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCS
Sbjct: 2053 PIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCS 2112
Query: 2041 IFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNM 2100
IFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNM
Sbjct: 2113 IFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNM 2172
Query: 2101 THLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLM 2160
THLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLM
Sbjct: 2173 THLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLM 2232
Query: 2161 IVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT 2220
IVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT
Sbjct: 2233 IVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT 2292
Query: 2221 RFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAM 2280
RFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAM
Sbjct: 2293 RFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAM 2352
Query: 2281 CHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCV 2340
CHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCV
Sbjct: 2353 CHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCV 2412
Query: 2341 CSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDL 2400
CSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDL
Sbjct: 2413 CSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDL 2472
Query: 2401 GCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDS 2460
GCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDS
Sbjct: 2473 GCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDS 2532
Query: 2461 CCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEA 2520
CCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEA
Sbjct: 2533 CCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEA 2592
Query: 2521 LTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVP 2580
LTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVP
Sbjct: 2593 LTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVP 2652
Query: 2581 RCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHT 2640
RCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHT
Sbjct: 2653 RCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHT 2712
Query: 2641 SRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTT 2700
SRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTT
Sbjct: 2713 SRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTT 2772
Query: 2701 SLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTC 2760
SLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTC
Sbjct: 2773 SLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTC 2832
Query: 2761 KEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVG 2820
KEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVG
Sbjct: 2833 KEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVG 2892
Query: 2821 LQRRSVQLFCATNATWVPYTVQEPTDCACQWS 2852
LQRRSVQLFCATNATWVPYTVQEPTDCACQWS
Sbjct: 2893 LQRRSVQLFCATNATWVPYTVQEPTDCACQWS 2924
>gi|239755901 PREDICTED: chromosome 12 open reading frame 64 [Homo
sapiens]
Length = 2250
Score = 1167 bits (3019), Expect = 0.0
Identities = 548/1385 (39%), Positives = 803/1385 (57%), Gaps = 72/1385 (5%)
Query: 39 FSCFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLS 98
+ C NG C CDC+ F A G RCQ++ N G RD IC+ WGQ+H ETFDG+YYY
Sbjct: 24 YECLNGAFCSKTGTCDCQIFQALGTRCQIIPNMGNGRDGICKTWGQYHFETFDGIYYYFP 83
Query: 99 GKGSYTLV---GRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHL-AKEVT 154
G SY G EP +++ VHN P+C S Y+C R++SLFF ++EI + E+
Sbjct: 84 GNCSYIFAKDCGDLEPR---YTVWVHNSPKCLGSVYSCYRSISLFFSNQEEIRIYGHEIK 140
Query: 155 HGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGN 214
G+ + LP +G +++LA Y++V+ F+LAWDG S +Y+K+S + G + GLCGN
Sbjct: 141 KNGISLTLPQTIGQIFIEKLADYILVKTTFGFSLAWDGISGIYLKLSEDHKGKSCGLCGN 200
Query: 215 NNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVY 274
N DD + T+D+ F +SW Q P+ T S PC P + ++
Sbjct: 201 YNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVLTPSDFPNPCSSGMPA-FEAIF 259
Query: 275 EQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQ 334
+C+ LL+ PF +CH Y+ P + ASC +DLC++ D T+CRA EYARAC+ AG P+Q
Sbjct: 260 FKCQILLQFPFLSCHEYIDPYLYIASCVNDLCKTDDD-ETYCRAATEYARACSHAGYPIQ 318
Query: 335 GWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGG 394
WR CT C + +F + +CI+CCP +C C+ S + C+DGCYCP+GL+ ++G
Sbjct: 319 DWRDDFPACTDKCDD-SFVHRDCISCCPPTCTFEKQCLGSNLHCLDGCYCPDGLVMDNGT 377
Query: 395 CVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDG 454
C++ CPC FHG Y GS ++++C C C G W C+ CP +CSV GD HFTTFDG
Sbjct: 378 CISLENCPCGFHGLAYSVGSKIEQECTECVCVGGVWNCTEQDCPVQCSVVGDSHFTTFDG 437
Query: 455 RRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQA 514
R Y+F CQYIL K FT+TLQ APC N C+QS+++IL D +QVTL +
Sbjct: 438 RHYSFIGMCQYILVKGTGKDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGRG 497
Query: 515 GDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVED 574
G +L + EI+ LSS+F+ ++T G+++L+ +G R+Y+Q+ W
Sbjct: 498 GQILTSPNQGF---NLNGIVEIQTLSSLFILLKTTFGLKILFAIDGERIYIQLTSAWKRR 554
Query: 575 TVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAAS 634
T+GLCGTFNGN +DDFLSP G+ E TPQL N+W+ S C V +DPC+++ Q
Sbjct: 555 TLGLCGTFNGNIRDDFLSPSGMIEGTPQLHANAWRVSSTCFAPVHVPVVDPCNINQQNIG 614
Query: 635 YSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPV 694
Y+ C V+ E+FAPC ++SP Y++ CR DAC+CG CLC LAHYA+LC +HG+P+
Sbjct: 615 YAAH-CDVIHQELFAPCHIYISPGLYYQLCRHDACKCGSSCLCNALAHYAYLCGQHGVPI 673
Query: 695 DFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPP 754
DFR ++ CA+ C+ Y C + C +C L+SPE C D+C EGC CP
Sbjct: 674 DFRTQISFCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCS---------DDCAEGCNCPE 724
Query: 755 DTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAA---C 811
+ + + CVP C CH++G Y PG+ G C C +G + CD A +A C
Sbjct: 725 GKFYEDTLNFCVPIFHCRCHYRGSVYQPGELIPTPSGLCQCSNGTVKCDELATPSAVHIC 784
Query: 812 PAGQVFVNCSDLHTDLE---LSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACF 868
P G+ + +C +L ++ E TC +N + + PC+SGC C G
Sbjct: 785 PEGKEYFDCRFPDPELPAGGVNCETTCANLAMNFTCTPSSPCISGCVCAPG--------- 835
Query: 869 LPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLP 928
VC+RG F CT +PC + CT YGDRHY +FDGL
Sbjct: 836 ---------------------------VCRRGMFNCTYYPCPAVCTIYGDRHYYSFDGLE 868
Query: 929 FDFVGACKVHLVKSTSDVSFSVIVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSP 988
+D++ C+V L+KS D SVI +N C+ + ++C K + I+VG++ I +D
Sbjct: 869 YDYISDCQVFLIKSADDSDISVIAQNKKCFDNDIVCSKSVLISVGDTEIYLNDTPYKQKQ 928
Query: 989 ESF-LDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDL 1047
F L++K W+ G++ +V+FP++ IT+LWD++TT+H++ GPQW+ +L+GLCGNFD
Sbjct: 929 SGFFLENKSTYQLWKAGYYIVVYFPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDK 988
Query: 1048 KTINEMRTPENLELTNPQEFGSSWAAVECPDTLDPRDMCVLNPLREPFAKKECSILLSEV 1107
T N+M T NLE+ N + FG SWA +C + C + + P+AKKECSIL S++
Sbjct: 989 CTSNDMTTSNNLEVRNARVFGDSWALGQCESPDETIKPCEAHQNKFPYAKKECSILYSDI 1048
Query: 1108 FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCP 1167
F C V+DVT F NC DTC C+ GGDCEC C S++AYA++CCQ G+++ WR+ +C
Sbjct: 1049 FASCRNVIDVTSFAKNCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIHWRSSTVCS 1108
Query: 1168 YDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVGDDIVLVRTEDVAPADIVSFLLTAALYK 1227
DC+++N+ LG+GPY L+S G ++G + + V + F++T L+K
Sbjct: 1109 LDCEYYNEGLGEGPYMLASYGQSGLVLGANMTSRSVFCLPRSSVHTSLFFYFMITPGLFK 1168
Query: 1228 AKAHDPDVVSLEAADRPNFFLHVTANGSLELAKWQGRDTFQQHASFLLHRGTRQAGLVAL 1287
K +VSLE+A+RPN+FL+V N +L L W+ F + A+F H+G G A
Sbjct: 1169 EKVSSLALVSLESAERPNYFLYVHDNDTLSLELWEANSAFHRRATFFHHQGLWIPGYSAF 1228
Query: 1288 ESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTLFRLLDAKPSGAAYPICEWRYDACASPC 1347
E +K F+ + + + Y+ +E F+ + F + + + + +CEWRY+ CA+PC
Sbjct: 1229 ELYSKKGFFIIFTDSSVKASKYDDSEEFKHSSSFSIEEIQAAVPYRKMCEWRYEPCATPC 1288
Query: 1348 FQTCRDPRAASCRDVPRVEGCVPVCPTPQVLDEVTQRCVYLEDCVEPAVWVPTEALGNET 1407
F+TC DP A +C+ +P VEGC+P CP +LDEVT +CVY DC+ +PTE
Sbjct: 1289 FKTCSDPEALACKFLPPVEGCLPYCPKNMILDEVTLKCVYPRDCIPV---IPTEP---TL 1342
Query: 1408 LPPSQ 1412
+PP++
Sbjct: 1343 MPPAK 1347
Score = 742 bits (1916), Expect = 0.0
Identities = 360/923 (39%), Positives = 506/923 (54%), Gaps = 20/923 (2%)
Query: 1941 PVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVPIAEQ------DCVRHICLE 1994
P + P+ + P ++ E + + T + T TT + Q DC ++ICL
Sbjct: 1337 PTEPTLMPPAKPTVPMFTVWEMITPSDITVFDMLTPTTGLECEPQKFDPVYDCSQYICLN 1396
Query: 1995 GQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSH 2054
+ N S +CP+ P CG G V+V D CCP WEC CRCS+ +LS +TFDG++
Sbjct: 1397 MEWQLYNWSLNCPKDVEMPDCGFRGRPVQVNSDICCPEWECPCRCSMLSELSIITFDGNN 1456
Query: 2055 VALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNR 2114
AL+ A YIL + P E++ H+ C C LN+T H++ ++R R
Sbjct: 1457 AALYSMASYILVRIPGEIIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLAR 1516
Query: 2115 KVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH- 2173
KV VD V P S IED+G MY+I TP+ + I+W H +G++ + +
Sbjct: 1517 KVEVDSIVVPLPFSSQELSIEDSGSMYVITTPAGLIIKWSHLTGIIDIHFGFRFNLSSYT 1576
Query: 2174 -GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDC 2232
GLCGIC+ D +DL +++G+++ ED F++SW++ S + R +C DC
Sbjct: 1577 EGLCGICNEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTMRRPVR--NCTEHDC 1634
Query: 2233 SPCLRMVSNRTFSACHRFVPPESFCE-LWIRDTKYVQQPCVALTVYVAMCHKFHVCIEWR 2291
S C+ +++ R F CH V PE FCE +WI T + C AL+ YVA+C+KF +CI+WR
Sbjct: 1635 SQCIDLLNRRIFIPCHDKVSPEDFCEKMWINYTYFWNYECDALSAYVALCNKFDICIQWR 1694
Query: 2292 RSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRH 2351
DYC C YQ CV CE G C L E CVC GT+LHR H
Sbjct: 1695 TPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTS---CLNLREDCVCKVGTVLHRPH 1751
Query: 2352 SALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCL 2411
SA CIPE +CACTDS PR GE WN + C ++C +I+P++ C C
Sbjct: 1752 SAQCIPEKECACTDSEDQPRTAGEIWNGGIDECTLYKCLENGSIIPIEPDCDEEPTPVCE 1811
Query: 2412 RFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCECDP 2471
R EV + + K CC VC C+ TLCE PTC +L+ SCCP Y CECDP
Sbjct: 1812 REAEVVMGIIDKWTCCSKEVCGCDTTLCETSIPTCTNSQKLIVGHSPLSCCPQYKCECDP 1871
Query: 2472 DLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEALTVHRNTTELC 2531
C + P CR+DQ +I R + CC S FC C C +P C +GE LTV N+T C
Sbjct: 1872 LKCPSISTPECREDQFMIQVRQEEPCCFSPFCVCESCTKPVPLCHDGEFLTVDLNSTHFC 1931
Query: 2532 CPLYQCVCENFRCPQ--VQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVPRCHLWEKSQ 2589
CP Y CVCE CP + C LV+ +CCP CEC+C+ + +P C + E +
Sbjct: 1932 CPQYYCVCEPNLCPMPLLNCAEDMNLVKENVSGQCCPTWHCECNCENLVMPTCEVGEFTA 1991
Query: 2590 LDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHTSRCTTVLDP 2649
+D H+ ++ CGC +Y C K VC+ +E+ V+ PGQ++++ + C+T C D
Sbjct: 1992 ID----HNFQSDCGCIQYLCEKDDVCVFQEVSVLNPGQSMIKYLEEDFCYTIECLEEKDN 2047
Query: 2650 LTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTTSLFLPGASW 2709
T F+ +N T V C C+ +Q Y CCG+C+NVSC F NGT+ ++ G++W
Sbjct: 2048 HTGFHTLNFTLVNCSKKCDVHQVYTPSPSDYGCCGTCKNVSCKFHMENGTSVVYAVGSTW 2107
Query: 2710 IADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTCKEDGRSCKK 2769
+C + C T GA+++ + CPP NETEC G V EGCC+ CK + R C+K
Sbjct: 2108 HYNCTTYECVKTDEGAIILNYTMVCPPFNETECKMSEGIVKLYNEGCCKICKREERICQK 2167
Query: 2770 VTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVGLQRRSVQLF 2829
V I+ IRK +C S +P+N+ SCDG+CPSA+IYN NI ++ RFCKCCRE G++ SV L+
Sbjct: 2168 VIIKSVIRKQDCMSQSPINVASCDGKCPSATIYNINIESHLRFCKCCRENGVRNLSVPLY 2227
Query: 2830 CATNATWVPYTVQEPTDCACQWS 2852
C+ N T + YT+QEP DC CQW+
Sbjct: 2228 CSGNGTEIMYTLQEPIDCTCQWN 2250
Score = 85.1 bits (209), Expect = 9e-16
Identities = 123/516 (23%), Positives = 187/516 (36%), Gaps = 105/516 (20%)
Query: 2004 QHCPQGAAPPRCGILGLA--------------VRVGGDRCCPLWECACRCSIFPDLSFVT 2049
++CP CG GLA V VGG C +C +CS+ D F T
Sbjct: 382 ENCP-------CGFHGLAYSVGSKIEQECTECVCVGGVWNCTEQDCPVQCSVVGDSHFTT 434
Query: 2050 FDGSHVALFKEAIYILSQSPDE---MLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQ 2106
FDG H + YIL + + +T+ C+ NLG + CL + +
Sbjct: 435 FDGRHYSFIGMCQYILVKGTGKDKFTITLQKAPCEQ-NLGLV-----CLQSITL------ 482
Query: 2107 VTIDRFNRKVTVDLQPVWPPVSRYGF------RIEDTGHMYMIL-TPSDIQIQWLHSSGL 2159
+ D FN++VT+ GF I+ ++++L T ++I +
Sbjct: 483 ILEDDFNKQVTLGRGGQILTSPNQGFNLNGIVEIQTLSSLFILLKTTFGLKILFAIDGER 542
Query: 2160 MIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQ 2219
+ ++ + K + GLCG +G+ +D G + G P ++W+V S
Sbjct: 543 IYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEG---TPQLHANAWRVSS------- 592
Query: 2220 TRFRPDSCATTDCSPC------------LRMVSNRTFSACHRFVPPESFCELWIRDTKYV 2267
T F P D PC ++ F+ CH ++ P + +L D
Sbjct: 593 TCFAPVHVPVVD--PCNINQQNIGYAAHCDVIHQELFAPCHIYISPGLYYQLCRHDACKC 650
Query: 2268 QQPCV--ALTVYVAMCHKFHVCIEWR-RSDYCPFLCSSDSTYQACVTACEPPKTCQDGIL 2324
C+ AL Y +C + V I++R + +C +C Y C C +
Sbjct: 651 GSSCLCNALAHYAYLCGQHGVPIDFRTQISFCAVVCQKGMLYHHC------SSFCLHSCI 704
Query: 2325 GPLDPEHC-QVLGEGCVCSEGTILHRRHSALCIPEAKCAC--TDSMGVPRALGETWNSSL 2381
PE C EGC C EG + C+P C C S+ P L T S L
Sbjct: 705 SLSSPEQCSDDCAEGCNCPEGK-FYEDTLNFCVPIFHCRCHYRGSVYQPGELIPT-PSGL 762
Query: 2382 SGCCQHQCQAPDTIVPVDLG-CPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCE 2440
C + + P + CP + RF + LP C +T C
Sbjct: 763 CQCSNGTVKCDELATPSAVHICPEGKEYFDCRFPDPE--LPAGGVNC--------ETTCA 812
Query: 2441 GLAP--TCRPGHRLLTHFQEDSCCPSYSCECDPDLC 2474
LA TC P S C S C C P +C
Sbjct: 813 NLAMNFTCTP----------SSPCIS-GCVCAPGVC 837
Score = 79.7 bits (195), Expect = 4e-14
Identities = 107/510 (20%), Positives = 172/510 (33%), Gaps = 117/510 (22%)
Query: 354 YNECIACCPASCHPRASCVDSEIACVDGC--YCPNGLIFEDGG--CVAPAEC----PCEF 405
Y C C +C + + V+GC YCP +I ++ CV P +C P E
Sbjct: 1281 YEPCATPCFKTCSDPEALACKFLPPVEGCLPYCPKNMILDEVTLKCVYPRDCIPVIPTE- 1339
Query: 406 HGTLYPPGSVVKE------------------------------------DCNTCTCTSGK 429
TL PP DC+ C + +
Sbjct: 1340 -PTLMPPAKPTVPMFTVWEMITPSDITVFDMLTPTTGLECEPQKFDPVYDCSQYICLNME 1398
Query: 430 WE-------------------------------CSTAVCPAECSVTGDIHFTTFDGRRYT 458
W+ C CP CS+ ++ TFDG
Sbjct: 1399 WQLYNWSLNCPKDVEMPDCGFRGRPVQVNSDICCPEWECPCRCSMLSELSIITFDGNNAA 1458
Query: 459 FPATCQYILAKSRSSGTFTVTLQNAPCGLNQ------DGACVQSVSVILHQDPRRQVTLT 512
+ YIL + + C +NQ G C + ++V P ++ +
Sbjct: 1459 LYSMASYILVRIPGE---IIVAHIEKCSMNQAPSGRISGLCFKKLNVTT---PIHKIIVN 1512
Query: 513 QAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRW- 571
+ + D + P++ I S+++ + T G+ + + + + R+
Sbjct: 1513 RLARKVEVDSIVVPLPFSSQELSIEDSGSMYV-ITTPAGLIIKWSHLTGIIDIHFGFRFN 1571
Query: 572 -VEDTVGLCGTFNGNTQDDFLSPVGVPESTPQ---LFGNSWKTLSACSPLVSGSPLDPCD 627
T GLCG N + DD G + + LF SW+ + + P+ C
Sbjct: 1572 LSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIGLFIESWE-IEKSFEVTMRRPVRNCT 1630
Query: 628 VHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQPCLCATLAHYAHLC 687
H + Q +L +F PC +SP + E+ + C L+ Y LC
Sbjct: 1631 EHDCS-----QCIDLLNRRIFIPCHDKVSPEDFCEKMWINYTYFWN-YECDALSAYVALC 1684
Query: 688 RRHGLPVDFRARLPACALSCEASKEYSPCVAPC-GRTC--QDLASPEACGVDGGDDLSRD 744
+ + + +R C+LSC KEY PCV PC RTC Q +C
Sbjct: 1685 NKFDICIQWRTP-DYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSC----------L 1733
Query: 745 ECVEGCACPPDTYLD-TQADLCVPRNQCSC 773
E C C T L + C+P +C+C
Sbjct: 1734 NLREDCVCKVGTVLHRPHSAQCIPEKECAC 1763
Score = 65.1 bits (157), Expect = 1e-09
Identities = 91/363 (25%), Positives = 135/363 (37%), Gaps = 64/363 (17%)
Query: 73 PERDSICRA--WGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSP 130
PE + CR + + TFDG L SY LV G+ I V + +C +
Sbjct: 1433 PEWECPCRCSMLSELSIITFDGNNAALYSMASYILV---RIPGE---IIVAHIEKCSMNQ 1486
Query: 131 YTCSRAVSLFFVG---EQEIH------LAKEVTHGGMRVQLPHVMGSARLQQLAGYVIVR 181
R L F IH LA++V + V LP ++ ++
Sbjct: 1487 APSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQELSIEDSGSMYVIT 1546
Query: 182 HQSAFTLAWD---GASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKL---TDDVV 235
+ + W G ++ L +T GLCG N DP DDL +G + +D+
Sbjct: 1547 TPAGLIIKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIG 1606
Query: 236 EFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALL-RPPFDACHAYVSP 294
F+ SW+ + + T P C + + QC LL R F CH VSP
Sbjct: 1607 LFIESWEIEKSFE----VTMRRPVRNCTEHD-------CSQCIDLLNRRIFIPCHDKVSP 1655
Query: 295 LPFTASCTSDLCQSMGDVATW-----CRALAEYARACAQAGRPLQGWRTQLRQCTVHCKE 349
D C+ M T+ C AL+ Y C + +Q WRT C++ C E
Sbjct: 1656 --------EDFCEKMWINYTYFWNYECDALSAYVALCNKFDICIQ-WRTP-DYCSLSCPE 1705
Query: 350 KAFTYNECIACCPA-SC-----HPRASCVDSEIACVDGCYCPNGLIF---EDGGCVAPAE 400
Y C+ C A +C + SC++ + C C G + C+ E
Sbjct: 1706 -GKEYQPCVRPCEARTCLNQWFYGHTSCLNLR----EDCVCKVGTVLHRPHSAQCIPEKE 1760
Query: 401 CPC 403
C C
Sbjct: 1761 CAC 1763
Score = 62.8 bits (151), Expect = 5e-09
Identities = 83/394 (21%), Positives = 137/394 (34%), Gaps = 62/394 (15%)
Query: 2007 PQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLS--------------FVTFDG 2052
P G+ P C + G C RC I P++ F TFDG
Sbjct: 18 PSGSCPYECLNGAFCSKTGTCDCQIFQALGTRCQIIPNMGNGRDGICKTWGQYHFETFDG 77
Query: 2053 SHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNW---PPFCLVMLNMTH------L 2103
+ YI ++ DC + W P CL + +
Sbjct: 78 IYYYFPGNCSYIFAK-----------DCGDLEPRYTVWVHNSPKCLGSVYSCYRSISLFF 126
Query: 2104 AHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVE 2163
++Q I + ++ + + P + IE ++ T + W SG+ + +
Sbjct: 127 SNQEEIRIYGHEIKKNGISLTLPQTIGQIFIEKLADYILVKTTFGFSLAWDGISGIYL-K 185
Query: 2164 ASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSW--QVPSSLTSVGQTR 2221
S+ K + GLCG + ++D + ED A F +SW Q P V
Sbjct: 186 LSEDHKGKSCGLCGNYNDIQSDDFIILQEDYT---EDIAMFANSWSVQTPDDTKCVLTPS 242
Query: 2222 FRPDSCATTDCSPCLRMVSNRT-------FSACHRFVPPESFCELWIRD---TKYVQQPC 2271
P+ C++ P + + F +CH ++ P + + D T + C
Sbjct: 243 DFPNPCSSG--MPAFEAIFFKCQILLQFPFLSCHEYIDPYLYIASCVNDLCKTDDDETYC 300
Query: 2272 VALTVYVAMCHKFHVCIEWRRSDY--CPFLCSSDSTYQACVTACEPPKTCQDGILGPLDP 2329
A T Y C I+ R D+ C C ++ C++ C P T + LG
Sbjct: 301 RAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTCTFEKQCLG--SN 358
Query: 2330 EHCQVLGEGCVCSEGTILHRRHSALCIPEAKCAC 2363
HC +GC C +G ++ + CI C C
Sbjct: 359 LHCL---DGCYCPDGLVM---DNGTCISLENCPC 386
Score = 44.3 bits (103), Expect = 0.002
Identities = 58/283 (20%), Positives = 104/283 (36%), Gaps = 27/283 (9%)
Query: 2030 CPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLN 2089
C + C C+I+ D + +FDG + L +S D+ + K +
Sbjct: 844 CTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLIKSADDSDISVIAQNKKCFDNDIV 903
Query: 2090 WPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPS-D 2148
L+ + T + T + +K Q + ++ +++ G+ ++ P D
Sbjct: 904 CSKSVLISVGDTEIYLNDT--PYKQK-----QSGFFLENKSTYQLWKAGYYIVVYFPEKD 956
Query: 2149 IQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSW 2208
I I W + + I + K + GLCG D +ND+T + V A F DSW
Sbjct: 957 ITILWDRKTTIHI-KVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNAR---VFGDSW 1012
Query: 2209 -----QVPSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRD 2263
+ P + A +CS ++ + F++C + SF + D
Sbjct: 1013 ALGQCESPDETIKPCEAHQNKFPYAKKECS----ILYSDIFASCRNVIDVTSFAKNCHED 1068
Query: 2264 T------KYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFLC 2300
T + C ++ Y C + + I WR S C C
Sbjct: 1069 TCNCNLGGDCECLCTSIAAYAYKCCQEGISIHWRSSTVCSLDC 1111
Score = 43.1 bits (100), Expect = 0.004
Identities = 100/480 (20%), Positives = 164/480 (34%), Gaps = 79/480 (16%)
Query: 713 YSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCA--CPPDTYLDTQADLCVPRNQ 770
Y PC PC +TC D PEA VEGC CP + LD CV
Sbjct: 1281 YEPCATPCFKTCSD---PEALACKFLPP------VEGCLPYCPKNMILDEVTLKCVYPRD 1331
Query: 771 CS--CHFQGVDYPPGDSDIP--SLGHCHCKDGVMSCDSRAPAAACPAG-QVFVNCSDLHT 825
C + PP +P ++ + D P Q F D
Sbjct: 1332 CIPVIPTEPTLMPPAKPTVPMFTVWEMITPSDITVFDMLTPTTGLECEPQKFDPVYDCSQ 1391
Query: 826 DLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPG 885
+ L+ E QL N S++ CP+ + E C ++G+
Sbjct: 1392 YICLNME----WQLYNWSLN----------CPKDV----------EMPDCGFRGRPVQVN 1427
Query: 886 DQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD 945
+ P C C+ C+ + TFDG LV+ +
Sbjct: 1428 SDICCPEWECPCR--------------CSMLSELSIITFDGNNAALYSMASYILVRIPGE 1473
Query: 946 VSFSVIVE-NVNCYSSGMI---CRKFISINVGNSLIVFDDDSGNPSPESFLD----DKQE 997
+ + I + ++N SG I C K +++ I+ + + +S + QE
Sbjct: 1474 IIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQE 1533
Query: 998 VHTWRVGFFTLVHFPQEHITLLWDQRT---TVHVQAGPQWQGQLAGLCGNFDLKTINEMR 1054
+ G ++ P I + W T +H GLCG + +++R
Sbjct: 1534 LSIEDSGSMYVITTPAGLI-IKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLR 1592
Query: 1055 TPENLELTNPQEFGSSWAAVECPDTLDPRDMCVLNPLREPFAKKECS----ILLSEVFEI 1110
+TN ++ G + E + + + + P+R + +CS +L +F
Sbjct: 1593 MQNGTIITNMEDIGLFIESWEIEKSFE---VTMRRPVRN-CTEHDCSQCIDLLNRRIFIP 1648
Query: 1111 CHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDC 1170
CH V F C + + EC ++SAY C + + + WRTP C C
Sbjct: 1649 CHDKVSPEDF---CEKMWINYTYFWNYEC--DALSAYVALCNKFDICIQWRTPDYCSLSC 1703
>gi|239750386 PREDICTED: chromosome 12 open reading frame 64 [Homo
sapiens]
Length = 2250
Score = 1167 bits (3019), Expect = 0.0
Identities = 548/1385 (39%), Positives = 803/1385 (57%), Gaps = 72/1385 (5%)
Query: 39 FSCFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLS 98
+ C NG C CDC+ F A G RCQ++ N G RD IC+ WGQ+H ETFDG+YYY
Sbjct: 24 YECLNGAFCSKTGTCDCQIFQALGTRCQIIPNMGNGRDGICKTWGQYHFETFDGIYYYFP 83
Query: 99 GKGSYTLV---GRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHL-AKEVT 154
G SY G EP +++ VHN P+C S Y+C R++SLFF ++EI + E+
Sbjct: 84 GNCSYIFAKDCGDLEPR---YTVWVHNSPKCLGSVYSCYRSISLFFSNQEEIRIYGHEIK 140
Query: 155 HGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGN 214
G+ + LP +G +++LA Y++V+ F+LAWDG S +Y+K+S + G + GLCGN
Sbjct: 141 KNGISLTLPQTIGQIFIEKLADYILVKTTFGFSLAWDGISGIYLKLSEDHKGKSCGLCGN 200
Query: 215 NNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVY 274
N DD + T+D+ F +SW Q P+ T S PC P + ++
Sbjct: 201 YNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVLTPSDFPNPCSSGMPA-FEAIF 259
Query: 275 EQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQ 334
+C+ LL+ PF +CH Y+ P + ASC +DLC++ D T+CRA EYARAC+ AG P+Q
Sbjct: 260 FKCQILLQFPFLSCHEYIDPYLYIASCVNDLCKTDDD-ETYCRAATEYARACSHAGYPIQ 318
Query: 335 GWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGG 394
WR CT C + +F + +CI+CCP +C C+ S + C+DGCYCP+GL+ ++G
Sbjct: 319 DWRDDFPACTDKCDD-SFVHRDCISCCPPTCTFEKQCLGSNLHCLDGCYCPDGLVMDNGT 377
Query: 395 CVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDG 454
C++ CPC FHG Y GS ++++C C C G W C+ CP +CSV GD HFTTFDG
Sbjct: 378 CISLENCPCGFHGLAYSVGSKIEQECTECVCVGGVWNCTEQDCPVQCSVVGDSHFTTFDG 437
Query: 455 RRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQA 514
R Y+F CQYIL K FT+TLQ APC N C+QS+++IL D +QVTL +
Sbjct: 438 RHYSFIGMCQYILVKGTGKDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGRG 497
Query: 515 GDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVED 574
G +L + EI+ LSS+F+ ++T G+++L+ +G R+Y+Q+ W
Sbjct: 498 GQILTSPNQGF---NLNGIVEIQTLSSLFILLKTTFGLKILFAIDGERIYIQLTSAWKRR 554
Query: 575 TVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAAS 634
T+GLCGTFNGN +DDFLSP G+ E TPQL N+W+ S C V +DPC+++ Q
Sbjct: 555 TLGLCGTFNGNIRDDFLSPSGMIEGTPQLHANAWRVSSTCFAPVHVPVVDPCNINQQNIG 614
Query: 635 YSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPV 694
Y+ C V+ E+FAPC ++SP Y++ CR DAC+CG CLC LAHYA+LC +HG+P+
Sbjct: 615 YAAH-CDVIHQELFAPCHIYISPGLYYQLCRHDACKCGSSCLCNALAHYAYLCGQHGVPI 673
Query: 695 DFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPP 754
DFR ++ CA+ C+ Y C + C +C L+SPE C D+C EGC CP
Sbjct: 674 DFRTQISFCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCS---------DDCAEGCNCPE 724
Query: 755 DTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAA---C 811
+ + + CVP C CH++G Y PG+ G C C +G + CD A +A C
Sbjct: 725 GKFYEDTLNFCVPIFHCRCHYRGSVYQPGELIPTPSGLCQCSNGTVKCDELATPSAVHIC 784
Query: 812 PAGQVFVNCSDLHTDLE---LSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACF 868
P G+ + +C +L ++ E TC +N + + PC+SGC C G
Sbjct: 785 PEGKEYFDCRFPDPELPAGGVNCETTCANLAMNFTCTPSSPCISGCVCAPG--------- 835
Query: 869 LPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLP 928
VC+RG F CT +PC + CT YGDRHY +FDGL
Sbjct: 836 ---------------------------VCRRGMFNCTYYPCPAVCTIYGDRHYYSFDGLE 868
Query: 929 FDFVGACKVHLVKSTSDVSFSVIVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSP 988
+D++ C+V L+KS D SVI +N C+ + ++C K + I+VG++ I +D
Sbjct: 869 YDYISDCQVFLIKSADDSDISVIAQNKKCFDNDIVCSKSVLISVGDTEIYLNDTPYKQKQ 928
Query: 989 ESF-LDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDL 1047
F L++K W+ G++ +V+FP++ IT+LWD++TT+H++ GPQW+ +L+GLCGNFD
Sbjct: 929 SGFFLENKSTYQLWKAGYYIVVYFPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDK 988
Query: 1048 KTINEMRTPENLELTNPQEFGSSWAAVECPDTLDPRDMCVLNPLREPFAKKECSILLSEV 1107
T N+M T NLE+ N + FG SWA +C + C + + P+AKKECSIL S++
Sbjct: 989 CTSNDMTTSNNLEVRNARVFGDSWALGQCESPDETIKPCEAHQNKFPYAKKECSILYSDI 1048
Query: 1108 FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCP 1167
F C V+DVT F NC DTC C+ GGDCEC C S++AYA++CCQ G+++ WR+ +C
Sbjct: 1049 FASCRNVIDVTSFAKNCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIHWRSSTVCS 1108
Query: 1168 YDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVGDDIVLVRTEDVAPADIVSFLLTAALYK 1227
DC+++N+ LG+GPY L+S G ++G + + V + F++T L+K
Sbjct: 1109 LDCEYYNEGLGEGPYMLASYGQSGLVLGANMTSRSVFCLPRSSVHTSLFFYFMITPGLFK 1168
Query: 1228 AKAHDPDVVSLEAADRPNFFLHVTANGSLELAKWQGRDTFQQHASFLLHRGTRQAGLVAL 1287
K +VSLE+A+RPN+FL+V N +L L W+ F + A+F H+G G A
Sbjct: 1169 EKVSSLALVSLESAERPNYFLYVHDNDTLSLELWEANSAFHRRATFFHHQGLWIPGYSAF 1228
Query: 1288 ESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTLFRLLDAKPSGAAYPICEWRYDACASPC 1347
E +K F+ + + + Y+ +E F+ + F + + + + +CEWRY+ CA+PC
Sbjct: 1229 ELYSKKGFFIIFTDSSVKASKYDDSEEFKHSSSFSIEEIQAAVPYRKMCEWRYEPCATPC 1288
Query: 1348 FQTCRDPRAASCRDVPRVEGCVPVCPTPQVLDEVTQRCVYLEDCVEPAVWVPTEALGNET 1407
F+TC DP A +C+ +P VEGC+P CP +LDEVT +CVY DC+ +PTE
Sbjct: 1289 FKTCSDPEALACKFLPPVEGCLPYCPKNMILDEVTLKCVYPRDCIPV---IPTEP---TL 1342
Query: 1408 LPPSQ 1412
+PP++
Sbjct: 1343 MPPAK 1347
Score = 742 bits (1916), Expect = 0.0
Identities = 361/923 (39%), Positives = 506/923 (54%), Gaps = 20/923 (2%)
Query: 1941 PVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVPIAEQ------DCVRHICLE 1994
P + P+ + P ++ E + + T + T TT + Q DC ++ICL
Sbjct: 1337 PTEPTLMPPAKPTVPMFTVWEMITPSDITVFDMLTPTTGLECEPQKFDPVYDCSQYICLN 1396
Query: 1995 GQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSH 2054
+ N S +CP+ P CG G V+V D CCP WEC CRCS+ +LS +TFDG++
Sbjct: 1397 MEWQLYNWSLNCPKDVEMPDCGFRGRPVQVNSDICCPEWECPCRCSMLSELSIITFDGNN 1456
Query: 2055 VALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNR 2114
AL+ A YIL + P E++ H+ C C LN+T H++ ++R R
Sbjct: 1457 AALYSMASYILVRIPGEIIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLAR 1516
Query: 2115 KVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH- 2173
KV VD V P S IED+G MY+I TP+ + I+W H +G++ + +
Sbjct: 1517 KVEVDSIVVPLPFSSQELSIEDSGSMYVITTPAGLIIKWSHLTGIIDIHFGFRFNLSSYT 1576
Query: 2174 -GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDC 2232
GLCGIC+ D +DL +++G+++ ED F++SW++ S + R +C DC
Sbjct: 1577 EGLCGICNEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTMRRPVR--NCTEHDC 1634
Query: 2233 SPCLRMVSNRTFSACHRFVPPESFCE-LWIRDTKYVQQPCVALTVYVAMCHKFHVCIEWR 2291
S C+ +++ R F CH V PE FCE +WI T + C AL+ YVA+C+KF +CI+WR
Sbjct: 1635 SQCIDLLNRRIFIPCHDKVSPEDFCEKMWINYTYFWNYECDALSAYVALCNKFDICIQWR 1694
Query: 2292 RSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRH 2351
DYC C YQ CV CE G C L E CVC GTILHR H
Sbjct: 1695 TPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTS---CLNLREDCVCKVGTILHRPH 1751
Query: 2352 SALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCL 2411
SA CIPE +CACTDS PR GE WN + C ++C +I+P++ C C
Sbjct: 1752 SAQCIPEKECACTDSEDQPRTAGEIWNGGIDECTLYKCLENGSIIPIEPDCDEEPTPVCE 1811
Query: 2412 RFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCECDP 2471
R EV + + K CC VC C+ TLCE PTC +L+ SCCP Y CECDP
Sbjct: 1812 REAEVVMGIIDKWTCCSKEVCGCDTTLCETSIPTCTNSQKLIVGHSPLSCCPQYKCECDP 1871
Query: 2472 DLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEALTVHRNTTELC 2531
C + P CR+DQ +I R + CC S FC C C +P C +GE LTV N+T C
Sbjct: 1872 LKCPSISTPECREDQFMIQVRQEEPCCFSPFCVCESCTKPVPLCHDGEFLTVDLNSTHFC 1931
Query: 2532 CPLYQCVCENFRCPQ--VQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVPRCHLWEKSQ 2589
CP Y CVCE CP + C LV+ +CCP CEC+C+ + +P C + E +
Sbjct: 1932 CPQYYCVCEPNLCPMPLLNCAEDMNLVKENVSGQCCPTWHCECNCENLVMPTCEVGEFTA 1991
Query: 2590 LDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHTSRCTTVLDP 2649
+D H+ ++ CGC +Y C K VC+ +E+ V+ PGQ++++ + C+T C D
Sbjct: 1992 ID----HNFQSDCGCIQYLCEKDDVCVFQEVSVLNPGQSMIKYLEEDFCYTIECLEEKDN 2047
Query: 2650 LTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTTSLFLPGASW 2709
T F+ +N T V C C+ +Q Y CCG+C+NVSC F NGT+ ++ G++W
Sbjct: 2048 HTGFHTLNFTLVNCSKKCDVHQVYTPSPSDYGCCGTCKNVSCKFHMENGTSVVYAVGSTW 2107
Query: 2710 IADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTCKEDGRSCKK 2769
+C + C T GA+++ + CPP NETEC G V EGCC+ CK + R C+K
Sbjct: 2108 HYNCTTYECVKTDEGAIILNYTMVCPPFNETECKMNEGIVKLYNEGCCKICKREERICQK 2167
Query: 2770 VTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVGLQRRSVQLF 2829
V I+ IRK +C S +P+N+ SCDG+CPSA+IYN NI ++ RFCKCCRE G++ SV L+
Sbjct: 2168 VIIKSVIRKQDCMSQSPINVASCDGKCPSATIYNINIESHLRFCKCCRENGVRNLSVPLY 2227
Query: 2830 CATNATWVPYTVQEPTDCACQWS 2852
C+ N T + YT+QEP DC CQW+
Sbjct: 2228 CSGNGTEIMYTLQEPIDCTCQWN 2250
Score = 85.1 bits (209), Expect = 9e-16
Identities = 123/516 (23%), Positives = 187/516 (36%), Gaps = 105/516 (20%)
Query: 2004 QHCPQGAAPPRCGILGLA--------------VRVGGDRCCPLWECACRCSIFPDLSFVT 2049
++CP CG GLA V VGG C +C +CS+ D F T
Sbjct: 382 ENCP-------CGFHGLAYSVGSKIEQECTECVCVGGVWNCTEQDCPVQCSVVGDSHFTT 434
Query: 2050 FDGSHVALFKEAIYILSQSPDE---MLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQ 2106
FDG H + YIL + + +T+ C+ NLG + CL + +
Sbjct: 435 FDGRHYSFIGMCQYILVKGTGKDKFTITLQKAPCEQ-NLGLV-----CLQSITL------ 482
Query: 2107 VTIDRFNRKVTVDLQPVWPPVSRYGF------RIEDTGHMYMIL-TPSDIQIQWLHSSGL 2159
+ D FN++VT+ GF I+ ++++L T ++I +
Sbjct: 483 ILEDDFNKQVTLGRGGQILTSPNQGFNLNGIVEIQTLSSLFILLKTTFGLKILFAIDGER 542
Query: 2160 MIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQ 2219
+ ++ + K + GLCG +G+ +D G + G P ++W+V S
Sbjct: 543 IYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEG---TPQLHANAWRVSS------- 592
Query: 2220 TRFRPDSCATTDCSPC------------LRMVSNRTFSACHRFVPPESFCELWIRDTKYV 2267
T F P D PC ++ F+ CH ++ P + +L D
Sbjct: 593 TCFAPVHVPVVD--PCNINQQNIGYAAHCDVIHQELFAPCHIYISPGLYYQLCRHDACKC 650
Query: 2268 QQPCV--ALTVYVAMCHKFHVCIEWR-RSDYCPFLCSSDSTYQACVTACEPPKTCQDGIL 2324
C+ AL Y +C + V I++R + +C +C Y C C +
Sbjct: 651 GSSCLCNALAHYAYLCGQHGVPIDFRTQISFCAVVCQKGMLYHHC------SSFCLHSCI 704
Query: 2325 GPLDPEHC-QVLGEGCVCSEGTILHRRHSALCIPEAKCAC--TDSMGVPRALGETWNSSL 2381
PE C EGC C EG + C+P C C S+ P L T S L
Sbjct: 705 SLSSPEQCSDDCAEGCNCPEGK-FYEDTLNFCVPIFHCRCHYRGSVYQPGELIPT-PSGL 762
Query: 2382 SGCCQHQCQAPDTIVPVDLG-CPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCE 2440
C + + P + CP + RF + LP C +T C
Sbjct: 763 CQCSNGTVKCDELATPSAVHICPEGKEYFDCRFPDPE--LPAGGVNC--------ETTCA 812
Query: 2441 GLAP--TCRPGHRLLTHFQEDSCCPSYSCECDPDLC 2474
LA TC P S C S C C P +C
Sbjct: 813 NLAMNFTCTP----------SSPCIS-GCVCAPGVC 837
Score = 79.7 bits (195), Expect = 4e-14
Identities = 107/510 (20%), Positives = 172/510 (33%), Gaps = 117/510 (22%)
Query: 354 YNECIACCPASCHPRASCVDSEIACVDGC--YCPNGLIFEDGG--CVAPAEC----PCEF 405
Y C C +C + + V+GC YCP +I ++ CV P +C P E
Sbjct: 1281 YEPCATPCFKTCSDPEALACKFLPPVEGCLPYCPKNMILDEVTLKCVYPRDCIPVIPTE- 1339
Query: 406 HGTLYPPGSVVKE------------------------------------DCNTCTCTSGK 429
TL PP DC+ C + +
Sbjct: 1340 -PTLMPPAKPTVPMFTVWEMITPSDITVFDMLTPTTGLECEPQKFDPVYDCSQYICLNME 1398
Query: 430 WE-------------------------------CSTAVCPAECSVTGDIHFTTFDGRRYT 458
W+ C CP CS+ ++ TFDG
Sbjct: 1399 WQLYNWSLNCPKDVEMPDCGFRGRPVQVNSDICCPEWECPCRCSMLSELSIITFDGNNAA 1458
Query: 459 FPATCQYILAKSRSSGTFTVTLQNAPCGLNQ------DGACVQSVSVILHQDPRRQVTLT 512
+ YIL + + C +NQ G C + ++V P ++ +
Sbjct: 1459 LYSMASYILVRIPGE---IIVAHIEKCSMNQAPSGRISGLCFKKLNVTT---PIHKIIVN 1512
Query: 513 QAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRW- 571
+ + D + P++ I S+++ + T G+ + + + + R+
Sbjct: 1513 RLARKVEVDSIVVPLPFSSQELSIEDSGSMYV-ITTPAGLIIKWSHLTGIIDIHFGFRFN 1571
Query: 572 -VEDTVGLCGTFNGNTQDDFLSPVGVPESTPQ---LFGNSWKTLSACSPLVSGSPLDPCD 627
T GLCG N + DD G + + LF SW+ + + P+ C
Sbjct: 1572 LSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIGLFIESWE-IEKSFEVTMRRPVRNCT 1630
Query: 628 VHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQPCLCATLAHYAHLC 687
H + Q +L +F PC +SP + E+ + C L+ Y LC
Sbjct: 1631 EHDCS-----QCIDLLNRRIFIPCHDKVSPEDFCEKMWINYTYFWN-YECDALSAYVALC 1684
Query: 688 RRHGLPVDFRARLPACALSCEASKEYSPCVAPC-GRTC--QDLASPEACGVDGGDDLSRD 744
+ + + +R C+LSC KEY PCV PC RTC Q +C
Sbjct: 1685 NKFDICIQWRTP-DYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSC----------L 1733
Query: 745 ECVEGCACPPDTYLD-TQADLCVPRNQCSC 773
E C C T L + C+P +C+C
Sbjct: 1734 NLREDCVCKVGTILHRPHSAQCIPEKECAC 1763
Score = 65.5 bits (158), Expect = 7e-10
Identities = 92/363 (25%), Positives = 135/363 (37%), Gaps = 64/363 (17%)
Query: 73 PERDSICRA--WGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSP 130
PE + CR + + TFDG L SY LV G+ I V + +C +
Sbjct: 1433 PEWECPCRCSMLSELSIITFDGNNAALYSMASYILV---RIPGE---IIVAHIEKCSMNQ 1486
Query: 131 YTCSRAVSLFFVG---EQEIH------LAKEVTHGGMRVQLPHVMGSARLQQLAGYVIVR 181
R L F IH LA++V + V LP ++ ++
Sbjct: 1487 APSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQELSIEDSGSMYVIT 1546
Query: 182 HQSAFTLAWD---GASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKL---TDDVV 235
+ + W G ++ L +T GLCG N DP DDL +G + +D+
Sbjct: 1547 TPAGLIIKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIG 1606
Query: 236 EFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALL-RPPFDACHAYVSP 294
F+ SW+ + + T P C + + QC LL R F CH VSP
Sbjct: 1607 LFIESWEIEKSFE----VTMRRPVRNCTEHD-------CSQCIDLLNRRIFIPCHDKVSP 1655
Query: 295 LPFTASCTSDLCQSMGDVATW-----CRALAEYARACAQAGRPLQGWRTQLRQCTVHCKE 349
D C+ M T+ C AL+ Y C + +Q WRT C++ C E
Sbjct: 1656 --------EDFCEKMWINYTYFWNYECDALSAYVALCNKFDICIQ-WRTP-DYCSLSCPE 1705
Query: 350 KAFTYNECIACCPA-SC-----HPRASCVDSEIACVDGCYCPNGLIF---EDGGCVAPAE 400
Y C+ C A +C + SC++ + C C G I C+ E
Sbjct: 1706 -GKEYQPCVRPCEARTCLNQWFYGHTSCLNLR----EDCVCKVGTILHRPHSAQCIPEKE 1760
Query: 401 CPC 403
C C
Sbjct: 1761 CAC 1763
Score = 62.8 bits (151), Expect = 5e-09
Identities = 83/394 (21%), Positives = 137/394 (34%), Gaps = 62/394 (15%)
Query: 2007 PQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLS--------------FVTFDG 2052
P G+ P C + G C RC I P++ F TFDG
Sbjct: 18 PSGSCPYECLNGAFCSKTGTCDCQIFQALGTRCQIIPNMGNGRDGICKTWGQYHFETFDG 77
Query: 2053 SHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNW---PPFCLVMLNMTH------L 2103
+ YI ++ DC + W P CL + +
Sbjct: 78 IYYYFPGNCSYIFAK-----------DCGDLEPRYTVWVHNSPKCLGSVYSCYRSISLFF 126
Query: 2104 AHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVE 2163
++Q I + ++ + + P + IE ++ T + W SG+ + +
Sbjct: 127 SNQEEIRIYGHEIKKNGISLTLPQTIGQIFIEKLADYILVKTTFGFSLAWDGISGIYL-K 185
Query: 2164 ASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSW--QVPSSLTSVGQTR 2221
S+ K + GLCG + ++D + ED A F +SW Q P V
Sbjct: 186 LSEDHKGKSCGLCGNYNDIQSDDFIILQEDYT---EDIAMFANSWSVQTPDDTKCVLTPS 242
Query: 2222 FRPDSCATTDCSPCLRMVSNRT-------FSACHRFVPPESFCELWIRD---TKYVQQPC 2271
P+ C++ P + + F +CH ++ P + + D T + C
Sbjct: 243 DFPNPCSSG--MPAFEAIFFKCQILLQFPFLSCHEYIDPYLYIASCVNDLCKTDDDETYC 300
Query: 2272 VALTVYVAMCHKFHVCIEWRRSDY--CPFLCSSDSTYQACVTACEPPKTCQDGILGPLDP 2329
A T Y C I+ R D+ C C ++ C++ C P T + LG
Sbjct: 301 RAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTCTFEKQCLG--SN 358
Query: 2330 EHCQVLGEGCVCSEGTILHRRHSALCIPEAKCAC 2363
HC +GC C +G ++ + CI C C
Sbjct: 359 LHCL---DGCYCPDGLVM---DNGTCISLENCPC 386
Score = 44.3 bits (103), Expect = 0.002
Identities = 58/283 (20%), Positives = 104/283 (36%), Gaps = 27/283 (9%)
Query: 2030 CPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLN 2089
C + C C+I+ D + +FDG + L +S D+ + K +
Sbjct: 844 CTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLIKSADDSDISVIAQNKKCFDNDIV 903
Query: 2090 WPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPS-D 2148
L+ + T + T + +K Q + ++ +++ G+ ++ P D
Sbjct: 904 CSKSVLISVGDTEIYLNDT--PYKQK-----QSGFFLENKSTYQLWKAGYYIVVYFPEKD 956
Query: 2149 IQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSW 2208
I I W + + I + K + GLCG D +ND+T + V A F DSW
Sbjct: 957 ITILWDRKTTIHI-KVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNAR---VFGDSW 1012
Query: 2209 -----QVPSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRD 2263
+ P + A +CS ++ + F++C + SF + D
Sbjct: 1013 ALGQCESPDETIKPCEAHQNKFPYAKKECS----ILYSDIFASCRNVIDVTSFAKNCHED 1068
Query: 2264 T------KYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFLC 2300
T + C ++ Y C + + I WR S C C
Sbjct: 1069 TCNCNLGGDCECLCTSIAAYAYKCCQEGISIHWRSSTVCSLDC 1111
Score = 43.1 bits (100), Expect = 0.004
Identities = 100/480 (20%), Positives = 164/480 (34%), Gaps = 79/480 (16%)
Query: 713 YSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCA--CPPDTYLDTQADLCVPRNQ 770
Y PC PC +TC D PEA VEGC CP + LD CV
Sbjct: 1281 YEPCATPCFKTCSD---PEALACKFLPP------VEGCLPYCPKNMILDEVTLKCVYPRD 1331
Query: 771 CS--CHFQGVDYPPGDSDIP--SLGHCHCKDGVMSCDSRAPAAACPAG-QVFVNCSDLHT 825
C + PP +P ++ + D P Q F D
Sbjct: 1332 CIPVIPTEPTLMPPAKPTVPMFTVWEMITPSDITVFDMLTPTTGLECEPQKFDPVYDCSQ 1391
Query: 826 DLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPG 885
+ L+ E QL N S++ CP+ + E C ++G+
Sbjct: 1392 YICLNME----WQLYNWSLN----------CPKDV----------EMPDCGFRGRPVQVN 1427
Query: 886 DQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD 945
+ P C C+ C+ + TFDG LV+ +
Sbjct: 1428 SDICCPEWECPCR--------------CSMLSELSIITFDGNNAALYSMASYILVRIPGE 1473
Query: 946 VSFSVIVE-NVNCYSSGMI---CRKFISINVGNSLIVFDDDSGNPSPESFLD----DKQE 997
+ + I + ++N SG I C K +++ I+ + + +S + QE
Sbjct: 1474 IIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQE 1533
Query: 998 VHTWRVGFFTLVHFPQEHITLLWDQRT---TVHVQAGPQWQGQLAGLCGNFDLKTINEMR 1054
+ G ++ P I + W T +H GLCG + +++R
Sbjct: 1534 LSIEDSGSMYVITTPAGLI-IKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLR 1592
Query: 1055 TPENLELTNPQEFGSSWAAVECPDTLDPRDMCVLNPLREPFAKKECS----ILLSEVFEI 1110
+TN ++ G + E + + + + P+R + +CS +L +F
Sbjct: 1593 MQNGTIITNMEDIGLFIESWEIEKSFE---VTMRRPVRN-CTEHDCSQCIDLLNRRIFIP 1648
Query: 1111 CHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDC 1170
CH V F C + + EC ++SAY C + + + WRTP C C
Sbjct: 1649 CHDKVSPEDF---CEKMWINYTYFWNYEC--DALSAYVALCNKFDICIQWRTPDYCSLSC 1703
>gi|239744688 PREDICTED: hypothetical protein LOC283310 [Homo sapiens]
Length = 2250
Score = 1167 bits (3019), Expect = 0.0
Identities = 548/1385 (39%), Positives = 803/1385 (57%), Gaps = 72/1385 (5%)
Query: 39 FSCFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLS 98
+ C NG C CDC+ F A G RCQ++ N G RD IC+ WGQ+H ETFDG+YYY
Sbjct: 24 YECLNGAFCSKTGTCDCQIFQALGTRCQIIPNMGNGRDGICKTWGQYHFETFDGIYYYFP 83
Query: 99 GKGSYTLV---GRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHL-AKEVT 154
G SY G EP +++ VHN P+C S Y+C R++SLFF ++EI + E+
Sbjct: 84 GNCSYIFAKDCGDLEPR---YTVWVHNSPKCLGSVYSCYRSISLFFSNQEEIRIYGHEIK 140
Query: 155 HGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGN 214
G+ + LP +G +++LA Y++V+ F+LAWDG S +Y+K+S + G + GLCGN
Sbjct: 141 KNGISLTLPQTIGQIFIEKLADYILVKTTFGFSLAWDGISGIYLKLSEDHKGKSCGLCGN 200
Query: 215 NNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVY 274
N DD + T+D+ F +SW Q P+ T S PC P + ++
Sbjct: 201 YNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVLTPSDFPNPCSSGMPA-FEAIF 259
Query: 275 EQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQ 334
+C+ LL+ PF +CH Y+ P + ASC +DLC++ D T+CRA EYARAC+ AG P+Q
Sbjct: 260 FKCQILLQFPFLSCHEYIDPYLYIASCVNDLCKTDDD-ETYCRAATEYARACSHAGYPIQ 318
Query: 335 GWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGG 394
WR CT C + +F + +CI+CCP +C C+ S + C+DGCYCP+GL+ ++G
Sbjct: 319 DWRDDFPACTDKCDD-SFVHRDCISCCPPTCTFEKQCLGSNLHCLDGCYCPDGLVMDNGT 377
Query: 395 CVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDG 454
C++ CPC FHG Y GS ++++C C C G W C+ CP +CSV GD HFTTFDG
Sbjct: 378 CISLENCPCGFHGLAYSVGSKIEQECTECVCVGGVWNCTEQDCPVQCSVVGDSHFTTFDG 437
Query: 455 RRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQA 514
R Y+F CQYIL K FT+TLQ APC N C+QS+++IL D +QVTL +
Sbjct: 438 RHYSFIGMCQYILVKGTGKDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGRG 497
Query: 515 GDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVED 574
G +L + EI+ LSS+F+ ++T G+++L+ +G R+Y+Q+ W
Sbjct: 498 GQILTSPNQGF---NLNGIVEIQTLSSLFILLKTTFGLKILFAIDGERIYIQLTSAWKRR 554
Query: 575 TVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAAS 634
T+GLCGTFNGN +DDFLSP G+ E TPQL N+W+ S C V +DPC+++ Q
Sbjct: 555 TLGLCGTFNGNIRDDFLSPSGMIEGTPQLHANAWRVSSTCFAPVHVPVVDPCNINQQNIG 614
Query: 635 YSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPV 694
Y+ C V+ E+FAPC ++SP Y++ CR DAC+CG CLC LAHYA+LC +HG+P+
Sbjct: 615 YAAH-CDVIHQELFAPCHIYISPGLYYQLCRHDACKCGSSCLCNALAHYAYLCGQHGVPI 673
Query: 695 DFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPP 754
DFR ++ CA+ C+ Y C + C +C L+SPE C D+C EGC CP
Sbjct: 674 DFRTQISFCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCS---------DDCAEGCNCPE 724
Query: 755 DTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAA---C 811
+ + + CVP C CH++G Y PG+ G C C +G + CD A +A C
Sbjct: 725 GKFYEDTLNFCVPIFHCRCHYRGSVYQPGELIPTPSGLCQCSNGTVKCDELATPSAVHIC 784
Query: 812 PAGQVFVNCSDLHTDLE---LSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACF 868
P G+ + +C +L ++ E TC +N + + PC+SGC C G
Sbjct: 785 PEGKEYFDCRFPDPELPAGGVNCETTCANLAMNFTCTPSSPCISGCVCAPG--------- 835
Query: 869 LPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLP 928
VC+RG F CT +PC + CT YGDRHY +FDGL
Sbjct: 836 ---------------------------VCRRGMFNCTYYPCPAVCTIYGDRHYYSFDGLE 868
Query: 929 FDFVGACKVHLVKSTSDVSFSVIVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSP 988
+D++ C+V L+KS D SVI +N C+ + ++C K + I+VG++ I +D
Sbjct: 869 YDYISDCQVFLIKSADDSDISVIAQNKKCFDNDIVCSKSVLISVGDTEIYLNDTPYKQKQ 928
Query: 989 ESF-LDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDL 1047
F L++K W+ G++ +V+FP++ IT+LWD++TT+H++ GPQW+ +L+GLCGNFD
Sbjct: 929 SGFFLENKSTYQLWKAGYYIVVYFPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDK 988
Query: 1048 KTINEMRTPENLELTNPQEFGSSWAAVECPDTLDPRDMCVLNPLREPFAKKECSILLSEV 1107
T N+M T NLE+ N + FG SWA +C + C + + P+AKKECSIL S++
Sbjct: 989 CTSNDMTTSNNLEVRNARVFGDSWALGQCESPDETIKPCEAHQNKFPYAKKECSILYSDI 1048
Query: 1108 FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCP 1167
F C V+DVT F NC DTC C+ GGDCEC C S++AYA++CCQ G+++ WR+ +C
Sbjct: 1049 FASCRNVIDVTSFAKNCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIHWRSSTVCS 1108
Query: 1168 YDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVGDDIVLVRTEDVAPADIVSFLLTAALYK 1227
DC+++N+ LG+GPY L+S G ++G + + V + F++T L+K
Sbjct: 1109 LDCEYYNEGLGEGPYMLASYGQSGLVLGANMTSRSVFCLPRSSVHTSLFFYFMITPGLFK 1168
Query: 1228 AKAHDPDVVSLEAADRPNFFLHVTANGSLELAKWQGRDTFQQHASFLLHRGTRQAGLVAL 1287
K +VSLE+A+RPN+FL+V N +L L W+ F + A+F H+G G A
Sbjct: 1169 EKVSSLALVSLESAERPNYFLYVHDNDTLSLELWEANSAFHRRATFFHHQGLWIPGYSAF 1228
Query: 1288 ESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTLFRLLDAKPSGAAYPICEWRYDACASPC 1347
E +K F+ + + + Y+ +E F+ + F + + + + +CEWRY+ CA+PC
Sbjct: 1229 ELYSKKGFFIIFTDSSVKASKYDDSEEFKHSSSFSIEEIQAAVPYRKMCEWRYEPCATPC 1288
Query: 1348 FQTCRDPRAASCRDVPRVEGCVPVCPTPQVLDEVTQRCVYLEDCVEPAVWVPTEALGNET 1407
F+TC DP A +C+ +P VEGC+P CP +LDEVT +CVY DC+ +PTE
Sbjct: 1289 FKTCSDPEALACKFLPPVEGCLPYCPKNMILDEVTLKCVYPRDCIPV---IPTEP---TL 1342
Query: 1408 LPPSQ 1412
+PP++
Sbjct: 1343 MPPAK 1347
Score = 740 bits (1910), Expect = 0.0
Identities = 360/923 (39%), Positives = 505/923 (54%), Gaps = 20/923 (2%)
Query: 1941 PVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVPIAEQ------DCVRHICLE 1994
P + P+ + P ++ E + + T + T TT + Q DC ++ICL
Sbjct: 1337 PTEPTLMPPAKPTVPMFTVWEMITPSDITVFDMLTPTTGLECEPQKFDPVYDCSQYICLN 1396
Query: 1995 GQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSH 2054
+ N S +CP+ P CG G V+V D CCP WEC CRCS+ +LS +TFDG++
Sbjct: 1397 MEWQLYNWSLNCPKDVEMPDCGFRGRPVQVNSDICCPEWECPCRCSMLSELSIITFDGNN 1456
Query: 2055 VALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNR 2114
AL+ A YIL + P E++ H+ C C LN+T H++ ++R R
Sbjct: 1457 AALYSMASYILVRIPGEIIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLAR 1516
Query: 2115 KVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH- 2173
KV VD V P S IED+G MY+I TP+ + I+W H +G++ + +
Sbjct: 1517 KVEVDSIVVPLPFSSQELSIEDSGSMYVITTPAGLIIKWSHLTGIIDIHFGFRFNLSSYT 1576
Query: 2174 -GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDC 2232
GLCGIC+ D +DL +++G+++ ED F++SW++ S + R +C DC
Sbjct: 1577 EGLCGICNEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTMRRPVR--NCTEHDC 1634
Query: 2233 SPCLRMVSNRTFSACHRFVPPESFCE-LWIRDTKYVQQPCVALTVYVAMCHKFHVCIEWR 2291
S C+ +++ R F CH V PE FCE +WI T + C AL+ YVA+C+KF +CI+WR
Sbjct: 1635 SQCIDLLNRRIFIPCHDKVSPEDFCEKMWINYTYFWNYECDALSAYVALCNKFDICIQWR 1694
Query: 2292 RSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRH 2351
DYC C YQ CV CE G C L E CVC GTILHR H
Sbjct: 1695 TPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTS---CLNLREDCVCKVGTILHRPH 1751
Query: 2352 SALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCL 2411
SA CIPE +CACTDS PR GE WN + C ++C +I+P++ C C
Sbjct: 1752 SAQCIPEKECACTDSEDQPRTAGEIWNGGIDECTLYKCLENGSIIPIEPDCDEEPTPVCE 1811
Query: 2412 RFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCECDP 2471
R EV + + K CC VC C+ TLCE PTC +L+ SCCP Y CECDP
Sbjct: 1812 REAEVVMGIIDKWTCCSKEVCGCDTTLCETSIPTCTNSQKLIVGHSPLSCCPQYKCECDP 1871
Query: 2472 DLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEALTVHRNTTELC 2531
C + P CR+DQ +I R + CC S FC C C +P C +GE LTV N+T C
Sbjct: 1872 LKCPSISTPECREDQFMIQVRQEEPCCFSPFCVCESCTKPVPLCHDGEFLTVDLNSTHFC 1931
Query: 2532 CPLYQCVCENFRCPQ--VQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVPRCHLWEKSQ 2589
CP Y CVCE CP + C LV+ +CCP CEC+C+ + +P C + E +
Sbjct: 1932 CPQYYCVCEPNLCPMPLLNCAEDMNLVKENVSGQCCPTWHCECNCENLIMPTCEVGEFTA 1991
Query: 2590 LDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHTSRCTTVLDP 2649
+D H+ ++ CGC +Y C K VC+ +E+ V+ PGQ++++ + C+ C D
Sbjct: 1992 ID----HNFQSDCGCIQYLCEKDDVCVFQEVSVLNPGQSMIKYLEEDFCYAIECLEEKDN 2047
Query: 2650 LTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTTSLFLPGASW 2709
T F+ +N T V C C+ +Q Y CCG+C+NVSC F NGT+ ++ G++W
Sbjct: 2048 HTGFHTLNFTLVNCSKKCDVHQVYTPSPSDYGCCGTCKNVSCKFHMENGTSVVYAVGSTW 2107
Query: 2710 IADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTCKEDGRSCKK 2769
+C + C T GA+++ + CPP NETEC G V EGCC+ CK + R C+K
Sbjct: 2108 HYNCTTYECVKTDEGAIILNYTMVCPPFNETECKMNEGIVKLYNEGCCKICKREERICQK 2167
Query: 2770 VTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVGLQRRSVQLF 2829
V I+ IRK +C S +P+N+ SCDG+CPSA+IYN NI ++ RFCKCCRE G++ SV L+
Sbjct: 2168 VIIKSVIRKQDCMSQSPINVASCDGKCPSATIYNINIESHLRFCKCCRENGVRNLSVPLY 2227
Query: 2830 CATNATWVPYTVQEPTDCACQWS 2852
C+ N T + YT+QEP DC CQW+
Sbjct: 2228 CSGNGTEIMYTLQEPIDCTCQWN 2250
Score = 85.1 bits (209), Expect = 9e-16
Identities = 123/516 (23%), Positives = 187/516 (36%), Gaps = 105/516 (20%)
Query: 2004 QHCPQGAAPPRCGILGLA--------------VRVGGDRCCPLWECACRCSIFPDLSFVT 2049
++CP CG GLA V VGG C +C +CS+ D F T
Sbjct: 382 ENCP-------CGFHGLAYSVGSKIEQECTECVCVGGVWNCTEQDCPVQCSVVGDSHFTT 434
Query: 2050 FDGSHVALFKEAIYILSQSPDE---MLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQ 2106
FDG H + YIL + + +T+ C+ NLG + CL + +
Sbjct: 435 FDGRHYSFIGMCQYILVKGTGKDKFTITLQKAPCEQ-NLGLV-----CLQSITL------ 482
Query: 2107 VTIDRFNRKVTVDLQPVWPPVSRYGF------RIEDTGHMYMIL-TPSDIQIQWLHSSGL 2159
+ D FN++VT+ GF I+ ++++L T ++I +
Sbjct: 483 ILEDDFNKQVTLGRGGQILTSPNQGFNLNGIVEIQTLSSLFILLKTTFGLKILFAIDGER 542
Query: 2160 MIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQ 2219
+ ++ + K + GLCG +G+ +D G + G P ++W+V S
Sbjct: 543 IYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEG---TPQLHANAWRVSS------- 592
Query: 2220 TRFRPDSCATTDCSPC------------LRMVSNRTFSACHRFVPPESFCELWIRDTKYV 2267
T F P D PC ++ F+ CH ++ P + +L D
Sbjct: 593 TCFAPVHVPVVD--PCNINQQNIGYAAHCDVIHQELFAPCHIYISPGLYYQLCRHDACKC 650
Query: 2268 QQPCV--ALTVYVAMCHKFHVCIEWR-RSDYCPFLCSSDSTYQACVTACEPPKTCQDGIL 2324
C+ AL Y +C + V I++R + +C +C Y C C +
Sbjct: 651 GSSCLCNALAHYAYLCGQHGVPIDFRTQISFCAVVCQKGMLYHHC------SSFCLHSCI 704
Query: 2325 GPLDPEHC-QVLGEGCVCSEGTILHRRHSALCIPEAKCAC--TDSMGVPRALGETWNSSL 2381
PE C EGC C EG + C+P C C S+ P L T S L
Sbjct: 705 SLSSPEQCSDDCAEGCNCPEGK-FYEDTLNFCVPIFHCRCHYRGSVYQPGELIPT-PSGL 762
Query: 2382 SGCCQHQCQAPDTIVPVDLG-CPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCE 2440
C + + P + CP + RF + LP C +T C
Sbjct: 763 CQCSNGTVKCDELATPSAVHICPEGKEYFDCRFPDPE--LPAGGVNC--------ETTCA 812
Query: 2441 GLAP--TCRPGHRLLTHFQEDSCCPSYSCECDPDLC 2474
LA TC P S C S C C P +C
Sbjct: 813 NLAMNFTCTP----------SSPCIS-GCVCAPGVC 837
Score = 79.7 bits (195), Expect = 4e-14
Identities = 107/510 (20%), Positives = 172/510 (33%), Gaps = 117/510 (22%)
Query: 354 YNECIACCPASCHPRASCVDSEIACVDGC--YCPNGLIFEDGG--CVAPAEC----PCEF 405
Y C C +C + + V+GC YCP +I ++ CV P +C P E
Sbjct: 1281 YEPCATPCFKTCSDPEALACKFLPPVEGCLPYCPKNMILDEVTLKCVYPRDCIPVIPTE- 1339
Query: 406 HGTLYPPGSVVKE------------------------------------DCNTCTCTSGK 429
TL PP DC+ C + +
Sbjct: 1340 -PTLMPPAKPTVPMFTVWEMITPSDITVFDMLTPTTGLECEPQKFDPVYDCSQYICLNME 1398
Query: 430 WE-------------------------------CSTAVCPAECSVTGDIHFTTFDGRRYT 458
W+ C CP CS+ ++ TFDG
Sbjct: 1399 WQLYNWSLNCPKDVEMPDCGFRGRPVQVNSDICCPEWECPCRCSMLSELSIITFDGNNAA 1458
Query: 459 FPATCQYILAKSRSSGTFTVTLQNAPCGLNQ------DGACVQSVSVILHQDPRRQVTLT 512
+ YIL + + C +NQ G C + ++V P ++ +
Sbjct: 1459 LYSMASYILVRIPGE---IIVAHIEKCSMNQAPSGRISGLCFKKLNVTT---PIHKIIVN 1512
Query: 513 QAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRW- 571
+ + D + P++ I S+++ + T G+ + + + + R+
Sbjct: 1513 RLARKVEVDSIVVPLPFSSQELSIEDSGSMYV-ITTPAGLIIKWSHLTGIIDIHFGFRFN 1571
Query: 572 -VEDTVGLCGTFNGNTQDDFLSPVGVPESTPQ---LFGNSWKTLSACSPLVSGSPLDPCD 627
T GLCG N + DD G + + LF SW+ + + P+ C
Sbjct: 1572 LSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIGLFIESWE-IEKSFEVTMRRPVRNCT 1630
Query: 628 VHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQPCLCATLAHYAHLC 687
H + Q +L +F PC +SP + E+ + C L+ Y LC
Sbjct: 1631 EHDCS-----QCIDLLNRRIFIPCHDKVSPEDFCEKMWINYTYFWN-YECDALSAYVALC 1684
Query: 688 RRHGLPVDFRARLPACALSCEASKEYSPCVAPC-GRTC--QDLASPEACGVDGGDDLSRD 744
+ + + +R C+LSC KEY PCV PC RTC Q +C
Sbjct: 1685 NKFDICIQWRTP-DYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSC----------L 1733
Query: 745 ECVEGCACPPDTYLD-TQADLCVPRNQCSC 773
E C C T L + C+P +C+C
Sbjct: 1734 NLREDCVCKVGTILHRPHSAQCIPEKECAC 1763
Score = 65.5 bits (158), Expect = 7e-10
Identities = 92/363 (25%), Positives = 135/363 (37%), Gaps = 64/363 (17%)
Query: 73 PERDSICRA--WGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSP 130
PE + CR + + TFDG L SY LV G+ I V + +C +
Sbjct: 1433 PEWECPCRCSMLSELSIITFDGNNAALYSMASYILV---RIPGE---IIVAHIEKCSMNQ 1486
Query: 131 YTCSRAVSLFFVG---EQEIH------LAKEVTHGGMRVQLPHVMGSARLQQLAGYVIVR 181
R L F IH LA++V + V LP ++ ++
Sbjct: 1487 APSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQELSIEDSGSMYVIT 1546
Query: 182 HQSAFTLAWD---GASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKL---TDDVV 235
+ + W G ++ L +T GLCG N DP DDL +G + +D+
Sbjct: 1547 TPAGLIIKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIG 1606
Query: 236 EFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALL-RPPFDACHAYVSP 294
F+ SW+ + + T P C + + QC LL R F CH VSP
Sbjct: 1607 LFIESWEIEKSFE----VTMRRPVRNCTEHD-------CSQCIDLLNRRIFIPCHDKVSP 1655
Query: 295 LPFTASCTSDLCQSMGDVATW-----CRALAEYARACAQAGRPLQGWRTQLRQCTVHCKE 349
D C+ M T+ C AL+ Y C + +Q WRT C++ C E
Sbjct: 1656 --------EDFCEKMWINYTYFWNYECDALSAYVALCNKFDICIQ-WRTP-DYCSLSCPE 1705
Query: 350 KAFTYNECIACCPA-SC-----HPRASCVDSEIACVDGCYCPNGLIF---EDGGCVAPAE 400
Y C+ C A +C + SC++ + C C G I C+ E
Sbjct: 1706 -GKEYQPCVRPCEARTCLNQWFYGHTSCLNLR----EDCVCKVGTILHRPHSAQCIPEKE 1760
Query: 401 CPC 403
C C
Sbjct: 1761 CAC 1763
Score = 62.8 bits (151), Expect = 5e-09
Identities = 83/394 (21%), Positives = 137/394 (34%), Gaps = 62/394 (15%)
Query: 2007 PQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLS--------------FVTFDG 2052
P G+ P C + G C RC I P++ F TFDG
Sbjct: 18 PSGSCPYECLNGAFCSKTGTCDCQIFQALGTRCQIIPNMGNGRDGICKTWGQYHFETFDG 77
Query: 2053 SHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNW---PPFCLVMLNMTH------L 2103
+ YI ++ DC + W P CL + +
Sbjct: 78 IYYYFPGNCSYIFAK-----------DCGDLEPRYTVWVHNSPKCLGSVYSCYRSISLFF 126
Query: 2104 AHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVE 2163
++Q I + ++ + + P + IE ++ T + W SG+ + +
Sbjct: 127 SNQEEIRIYGHEIKKNGISLTLPQTIGQIFIEKLADYILVKTTFGFSLAWDGISGIYL-K 185
Query: 2164 ASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSW--QVPSSLTSVGQTR 2221
S+ K + GLCG + ++D + ED A F +SW Q P V
Sbjct: 186 LSEDHKGKSCGLCGNYNDIQSDDFIILQEDYT---EDIAMFANSWSVQTPDDTKCVLTPS 242
Query: 2222 FRPDSCATTDCSPCLRMVSNRT-------FSACHRFVPPESFCELWIRD---TKYVQQPC 2271
P+ C++ P + + F +CH ++ P + + D T + C
Sbjct: 243 DFPNPCSSG--MPAFEAIFFKCQILLQFPFLSCHEYIDPYLYIASCVNDLCKTDDDETYC 300
Query: 2272 VALTVYVAMCHKFHVCIEWRRSDY--CPFLCSSDSTYQACVTACEPPKTCQDGILGPLDP 2329
A T Y C I+ R D+ C C ++ C++ C P T + LG
Sbjct: 301 RAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTCTFEKQCLG--SN 358
Query: 2330 EHCQVLGEGCVCSEGTILHRRHSALCIPEAKCAC 2363
HC +GC C +G ++ + CI C C
Sbjct: 359 LHCL---DGCYCPDGLVM---DNGTCISLENCPC 386
Score = 44.3 bits (103), Expect = 0.002
Identities = 58/283 (20%), Positives = 104/283 (36%), Gaps = 27/283 (9%)
Query: 2030 CPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLN 2089
C + C C+I+ D + +FDG + L +S D+ + K +
Sbjct: 844 CTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLIKSADDSDISVIAQNKKCFDNDIV 903
Query: 2090 WPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPS-D 2148
L+ + T + T + +K Q + ++ +++ G+ ++ P D
Sbjct: 904 CSKSVLISVGDTEIYLNDT--PYKQK-----QSGFFLENKSTYQLWKAGYYIVVYFPEKD 956
Query: 2149 IQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSW 2208
I I W + + I + K + GLCG D +ND+T + V A F DSW
Sbjct: 957 ITILWDRKTTIHI-KVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNAR---VFGDSW 1012
Query: 2209 -----QVPSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRD 2263
+ P + A +CS ++ + F++C + SF + D
Sbjct: 1013 ALGQCESPDETIKPCEAHQNKFPYAKKECS----ILYSDIFASCRNVIDVTSFAKNCHED 1068
Query: 2264 T------KYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFLC 2300
T + C ++ Y C + + I WR S C C
Sbjct: 1069 TCNCNLGGDCECLCTSIAAYAYKCCQEGISIHWRSSTVCSLDC 1111
Score = 43.1 bits (100), Expect = 0.004
Identities = 100/480 (20%), Positives = 164/480 (34%), Gaps = 79/480 (16%)
Query: 713 YSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCA--CPPDTYLDTQADLCVPRNQ 770
Y PC PC +TC D PEA VEGC CP + LD CV
Sbjct: 1281 YEPCATPCFKTCSD---PEALACKFLPP------VEGCLPYCPKNMILDEVTLKCVYPRD 1331
Query: 771 CS--CHFQGVDYPPGDSDIP--SLGHCHCKDGVMSCDSRAPAAACPAG-QVFVNCSDLHT 825
C + PP +P ++ + D P Q F D
Sbjct: 1332 CIPVIPTEPTLMPPAKPTVPMFTVWEMITPSDITVFDMLTPTTGLECEPQKFDPVYDCSQ 1391
Query: 826 DLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPG 885
+ L+ E QL N S++ CP+ + E C ++G+
Sbjct: 1392 YICLNME----WQLYNWSLN----------CPKDV----------EMPDCGFRGRPVQVN 1427
Query: 886 DQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD 945
+ P C C+ C+ + TFDG LV+ +
Sbjct: 1428 SDICCPEWECPCR--------------CSMLSELSIITFDGNNAALYSMASYILVRIPGE 1473
Query: 946 VSFSVIVE-NVNCYSSGMI---CRKFISINVGNSLIVFDDDSGNPSPESFLD----DKQE 997
+ + I + ++N SG I C K +++ I+ + + +S + QE
Sbjct: 1474 IIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQE 1533
Query: 998 VHTWRVGFFTLVHFPQEHITLLWDQRT---TVHVQAGPQWQGQLAGLCGNFDLKTINEMR 1054
+ G ++ P I + W T +H GLCG + +++R
Sbjct: 1534 LSIEDSGSMYVITTPAGLI-IKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLR 1592
Query: 1055 TPENLELTNPQEFGSSWAAVECPDTLDPRDMCVLNPLREPFAKKECS----ILLSEVFEI 1110
+TN ++ G + E + + + + P+R + +CS +L +F
Sbjct: 1593 MQNGTIITNMEDIGLFIESWEIEKSFE---VTMRRPVRN-CTEHDCSQCIDLLNRRIFIP 1648
Query: 1111 CHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDC 1170
CH V F C + + EC ++SAY C + + + WRTP C C
Sbjct: 1649 CHDKVSPEDF---CEKMWINYTYFWNYEC--DALSAYVALCNKFDICIQWRTPDYCSLSC 1703
>gi|89191868 von Willebrand factor preproprotein [Homo sapiens]
Length = 2813
Score = 654 bits (1688), Expect = 0.0
Identities = 393/1135 (34%), Positives = 560/1135 (49%), Gaps = 80/1135 (7%)
Query: 79 CRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVS 138
C +G V TFDG Y +G SY L G + S N + S Y +
Sbjct: 35 CSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRSFSIIGDFQNGKRVSLSVY-----LG 89
Query: 139 LFFVGEQEIHLAKE--VTHGGMRVQLPHVMGSARLQQLAGYVIVRHQS-AFTLAWDGASA 195
FF +IHL VT G RV +P+ L+ AGY + ++ F DG+
Sbjct: 90 EFF----DIHLFVNGTVTQGDQRVSMPYASKGLYLETEAGYYKLSGEAYGFVARIDGSGN 145
Query: 196 VYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTS 255
+ +S T GLCGN N +DD +T G LT D +F +SW + Q +
Sbjct: 146 FQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQ--WCERA 203
Query: 256 SLPRPPCLQQNPGTMQGVYEQCEALLRPP-FDACHAYVSPLPFTASCTSDLCQSMGDVAT 314
S P C + +G++EQC+ L F CH V P PF A C LC+ G +
Sbjct: 204 SPPSSSCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVDPEPFVALCEKTLCECAGGLEC 263
Query: 315 WCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASC---HPRASC 371
C AL EYAR CAQ G L GW T C+ C Y +C++ C +C H C
Sbjct: 264 ACPALLEYARTCAQEGMVLYGW-TDHSACSPVCPA-GMEYRQCVSPCARTCQSLHINEMC 321
Query: 372 VDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWE 431
+ CVDGC CP G + ++G CV ECPC G YPPG+ + DCNTC C + +W
Sbjct: 322 QER---CVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYPPGTSLSRDCNTCICRNSQWI 378
Query: 432 CSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDG 491
CS CP EC VTG HF +FD R +TF CQY+LA+ +F++ ++ C ++D
Sbjct: 379 CSNEECPGECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQDHSFSIVIETVQCADDRDA 438
Query: 492 ACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVG 551
C +SV+V L V L V + Q +P D +R +V VR + G
Sbjct: 439 VCTRSVTVRLPGLHNSLVKLKHGAGVAMDGQDVQLPLLKGD---LRIQHTVTASVRLSYG 495
Query: 552 VRVLYDREGL-RLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKT 610
+ D +G RL +++ + T GLCG +NGN DDFL+P G+ E + FGN+WK
Sbjct: 496 EDLQMDWDGRGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKL 555
Query: 611 LSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACR 670
C L DPC ++ + +S +AC+VLT F C +SP+PY CR D C
Sbjct: 556 HGDCQDL-QKQHSDPCALNPRMTRFSEEACAVLTSPTFEACHRAVSPLPYLRNCRYDVCS 614
Query: 671 C--GQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLA 728
C G+ CLC LA YA C G+ V +R C L+C + Y C PC TC+ L+
Sbjct: 615 CSDGRECLCGALASYAAACAGRGVRVAWR-EPGRCELNCPKGQVYLQCGTPCNLTCRSLS 673
Query: 729 SPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIP 788
P D+ + C+EGC CPP Y+D + D CVP+ QC C++ G + P D
Sbjct: 674 YP--------DEECNEACLEGCFCPPGLYMDERGD-CVPKAQCPCYYDGEIFQPEDIFSD 724
Query: 789 SLGHCHCKDGVMSCD-SRAPAA-------------------ACPAGQVFVNCSDLHTDLE 828
C+C+DG M C S P + +C V + C + E
Sbjct: 725 HHTMCYCEDGFMHCTMSGVPGSLLPDAVLSSPLSHRSKRSLSCRPPMVKLVCPADNLRAE 784
Query: 829 -LSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQ 887
L +TC Q +L + G C+SGC CP G++RH + C E CPC +GKEY PG+
Sbjct: 785 GLECTKTC--QNYDLECMSMG-CVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGET 841
Query: 888 VMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVK---STS 944
V C+TCVC+ + CT H C +TC+ G HY TFDGL + F G C+ LV+ ++
Sbjct: 842 VKIGCNTCVCRDRKWNCTDHVCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSN 901
Query: 945 DVSFSVIVENVNCYSSGMICRKFISINV-GNSLIVFDDDSGNPSPESFLDDKQEVHTWRV 1003
+F ++V N C + C+K ++I V G + +FD + P + D+
Sbjct: 902 PGTFRILVGNKGCSHPSVKCKKRVTILVEGGEIELFDGEVNVKRP---MKDETHFEVVES 958
Query: 1004 GFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLEL-T 1062
G + ++ + ++++WD+ ++ V +Q ++ GLCGNFD N++ T NL++
Sbjct: 959 GRYIILLLGKA-LSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDL-TSSNLQVEE 1016
Query: 1063 NPQEFGSSW-AAVECPDTLD-PRD----MCVLNPLREPFAKKECSILLSEVFEICHPVVD 1116
+P +FG+SW + +C DT P D C N +++ C IL S+VF+ C+ +VD
Sbjct: 1017 DPVDFGNSWKVSSQCADTRKVPLDSSPATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVD 1076
Query: 1117 VTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCD 1171
+ C+ DTC C GDC CFC +++AYAH C QHG V WRT LCP C+
Sbjct: 1077 PEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVVTWRTATLCPQSCE 1131
Score = 240 bits (612), Expect = 2e-62
Identities = 232/952 (24%), Positives = 362/952 (38%), Gaps = 148/952 (15%)
Query: 1994 EGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGS 2053
+GQ + + +C +G P C V+V + C W C C C+ VTFDG
Sbjct: 1907 DGQTLLKSHRVNCDRGLRPS-CPNSQSPVKVE-ETCGCRWTCPCVCTGSSTRHIVTFDGQ 1964
Query: 2054 HVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFN 2113
+ L Y+L Q+ ++ L V +L + + G C+ + + H A V + +
Sbjct: 1965 NFKLTGSCSYVLFQNKEQDLEV-ILHNGACSPGARQG---CMKSIEVKHSALSVELHS-D 2019
Query: 2114 RKVTVDLQPVWPP-------VSRYG-----FRIEDTGHMYMILTPSDIQIQWLHSSGLMI 2161
+VTV+ + V P V+ YG R GH++ TP + + Q +
Sbjct: 2020 MEVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLGHIFTF-TPQNNEFQ--------L 2070
Query: 2162 VEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT- 2220
+ KT ++ +GLCGICD + AND L+DG+V D + W V GQT
Sbjct: 2071 QLSPKTFASKTYGLCGICDENGANDFMLRDGTVT---TDWKTLVQEWTVQRP----GQTC 2123
Query: 2221 -RFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVA 2279
+ C D S C +++ F+ CH+ + P +F + +D+ + +Q C + Y
Sbjct: 2124 QPILEEQCLVPDSSHC-QVLLLPLFAECHKVLAPATFYAICQQDSCHQEQVCEVIASYAH 2182
Query: 2280 MCHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGC 2339
+C VC++WR D+C C Y C C P+ C + D EGC
Sbjct: 2183 LCRTNGVCVDWRTPDFCAMSCPPSLVYNHCEHGC--PRHCDGNVSSCGDHP-----SEGC 2235
Query: 2340 VCSEGTILHRRHSALCIPEAKCA-CTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPV 2398
C ++ C+PE C C GV E W C C + +
Sbjct: 2236 FCPPDKVMLE---GSCVPEEACTQCIGEDGVQHQFLEAWVPDHQPCQICTCLSGRKVNCT 2292
Query: 2399 DLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCE-GLAPTCRPGHRLLTHFQ 2457
CP+ + +C EVA L D CC CVC+ C+ P C G + T
Sbjct: 2293 TQPCPTAKAPTC-GLCEVARLRQNADQCCPEYECVCDPVSCDLPPVPHCERGLQP-TLTN 2350
Query: 2458 EDSCCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQE 2517
C P+++C C + C+ PSC ++ + CC Y CAC +C +S C
Sbjct: 2351 PGECRPNFTCACRKEECKRVSPPSCPPHRLPTLRKT--QCCDEYECAC-NCVNSTVSCPL 2407
Query: 2518 G-------------------EALTVHRNTTELCCPLYQ-----CVCENF----------R 2543
G + + VHR+T ++ C C + +
Sbjct: 2408 GYLASTATNDCGCTTTTCLPDKVCVHRSTIYPVGQFWEEGCDVCTCTDMEDAVMGLRVAQ 2467
Query: 2544 CPQVQC------GLGTALVEVWSPDRCCPYKSCECDCDT-----------------IPVP 2580
C Q C G L E RC P +CE + P
Sbjct: 2468 CSQKPCEDSCRSGFTYVLHEGECCGRCLP-SACEVVTGSPRGDSQSSWKSVGSQWASPEN 2526
Query: 2581 RCHLWEKSQLDEE---------------------FMHSVENVCGCAKYECVKAPVCLSRE 2619
C + E ++ EE F S + C C + C+
Sbjct: 2527 PCLINECVRVKEEVFIQQRNVSCPQLEVPVCPSGFQLSCKTSACCPSCRCERMEACMLNG 2586
Query: 2620 LGVMQPGQTVVELSADGVCHTSRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDL 2679
V+ PG+TV+ VC T RC + ++ F ++ C+ C Y+ +
Sbjct: 2587 T-VIGPGKTVMI----DVCTTCRCMVQVGVISGF-KLECRKTTCN-PCPLG--YKEENNT 2637
Query: 2680 AACCGSCRNVSCLFTFPNGTTSLFLPGASWIADCARHHCSSTPLGAVLVRSPIS-CPPLN 2738
CCG C +C G + C H C G ++ CPP +
Sbjct: 2638 GECCGRCLPTACTIQLRGGQIMTLKRDETLQDGCDTHFCKVNERGEYFWEKRVTGCPPFD 2697
Query: 2739 ETECAKVGGSVVPSLEGCCRTCKEDGRSCKKVTIRMT-IRKNECRSSTPVNLVSCDGRCP 2797
E +C GG ++ CC TC+E C +T R+ ++ C+S V++ C G+C
Sbjct: 2698 EHKCLAEGGKIMKIPGTCCDTCEEP--ECNDITARLQYVKVGSCKSEVEVDIHYCQGKCA 2755
Query: 2798 SASIYNYNINTYARFCKCCREVGLQRRSVQLFCATNATWVPYTVQEPTDCAC 2849
S ++Y+ +IN C CC + V L C TN + V + V +C C
Sbjct: 2756 SKAMYSIDINDVQDQCSCCSPTRTEPMQVALHC-TNGSVVYHEVLNAMECKC 2806
Score = 233 bits (594), Expect = 2e-60
Identities = 150/461 (32%), Positives = 207/461 (44%), Gaps = 58/461 (12%)
Query: 376 IACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTA 435
+ CV GC CP G++ + CVA CPC G Y PG VK CNTC C KW C+
Sbjct: 802 MGCVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGETVKIGCNTCVCRDRKWNCTDH 861
Query: 436 VCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKS---RSSGTFTVTLQNAPCGLNQDGA 492
VC A CS G H+ TFDG +Y FP CQY+L + + GTF + + N C +
Sbjct: 862 VCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRILVGNKGCS-HPSVK 920
Query: 493 CVQSVSVILHQDPRRQVTLTQAGDVLLFD-QYKIIPPYTDDA-FEIRRLSSVFLRVRTNV 550
C + V++ L + G++ LFD + + P D+ FE+ S ++ +
Sbjct: 921 CKKRVTI-----------LVEGGEIELFDGEVNVKRPMKDETHFEVVE-SGRYIILLLGK 968
Query: 551 GVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKT 610
+ V++DR L + + + Q + E GLCG F+G +D S E P FGNSWK
Sbjct: 969 ALSVVWDRH-LSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKV 1027
Query: 611 LSACSPLVSGSPLDP----CDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRR 666
S C+ PLD C ++ + +C +LT ++F C+ + P PY + C
Sbjct: 1028 SSQCAD-TRKVPLDSSPATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVDPEPYLDVCIY 1086
Query: 667 DACRCGQ----PCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASK----------E 712
D C C C C T+A YAH+C +HG V +R C SCE
Sbjct: 1087 DTCSCESIGDCACFCDTIAAYAHVCAQHGKVVTWRTAT-LCPQSCEERNLRENGYECEWR 1145
Query: 713 YSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCA--CPPDTYLDTQADLCVPRNQ 770
Y+ C C TCQ P AC V +CVEGC CPP LD CV
Sbjct: 1146 YNSCAPACQVTCQH-PEPLACPV---------QCVEGCHAHCPPGKILDELLQTCVDPED 1195
Query: 771 CS-CHFQGVDYPPG------DSDIPSLGHCHCKDGVMSCDS 804
C C G + G SD CHC ++C++
Sbjct: 1196 CPVCEVAGRRFASGKKVTLNPSDPEHCQICHCDVVNLTCEA 1236
Score = 157 bits (396), Expect = 2e-37
Identities = 110/380 (28%), Positives = 157/380 (41%), Gaps = 31/380 (8%)
Query: 439 AECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVS 498
A CS+ G TFDG Y+F C Y+LA +F++ G Q+G + VS
Sbjct: 33 ARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRSFSI------IGDFQNG---KRVS 83
Query: 499 VILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDR 558
+ ++ + L G V DQ ++ PY + + + G D
Sbjct: 84 LSVYLGEFFDIHLFVNGTVTQGDQ-RVSMPYASKGLYLETEAGYYKLSGEAYGFVARIDG 142
Query: 559 EGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA---CS 615
G + + R+ T GLCG FN +DDF++ G S P F NSW S C
Sbjct: 143 SG-NFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQWCE 201
Query: 616 PLVSGSPLDPCDVHLQAASYSV-QACSVL-TGEMFAPCSAFLSPVPYFEQCRRDACRC-- 671
+ P C++ + + C +L + +FA C + P P+ C + C C
Sbjct: 202 R--ASPPSSSCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVDPEPFVALCEKTLCECAG 259
Query: 672 GQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPE 731
G C C L YA C + G+ + AC+ C A EY CV+PC RTCQ L E
Sbjct: 260 GLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQSLHINE 319
Query: 732 ACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLG 791
C ++ CV+GC+CP LD LCV +C C G YPPG S
Sbjct: 320 MC---------QERCVDGCSCPEGQLLD--EGLCVESTECPCVHSGKRYPPGTSLSRDCN 368
Query: 792 HCHCKDGVMSCDSRAPAAAC 811
C C++ C + C
Sbjct: 369 TCICRNSQWICSNEECPGEC 388
Score = 136 bits (342), Expect = 3e-31
Identities = 124/453 (27%), Positives = 180/453 (39%), Gaps = 72/453 (15%)
Query: 29 HRAKCAPSYLFSCFNGGECVHPA----------FCDCRRFNATGPRCQMVYNAGPERDSI 78
H +C CF+ G+ P C R++N T C D+
Sbjct: 817 HENRCVALERCPCFHQGKEYAPGETVKIGCNTCVCRDRKWNCTDHVC----------DAT 866
Query: 79 CRAWGQHHVETFDGLYYYLSGKGSYTLVGRH-EPEGQSFSIQVHNDPQCGSSPYTCSRAV 137
C G H TFDGL Y G+ Y LV + +F I V N C C + V
Sbjct: 867 CSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRILVGN-KGCSHPSVKCKKRV 925
Query: 138 SLFFVGEQEIHLAKEVTHGGMRVQLP-------HVMGSARLQQLAGYVIVRHQSAFTLAW 190
++ G + E+ G + V+ P V+ S R Y+I+ A ++ W
Sbjct: 926 TILVEGGE-----IELFDGEVNVKRPMKDETHFEVVESGR------YIILLLGKALSVVW 974
Query: 191 DGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ--EQAPNQ 248
D ++ + + GLCGN + +DL +S+ ++ +D V+F +SW+ Q +
Sbjct: 975 DRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKVSSQCADT 1034
Query: 249 PPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDL--C 306
P SS P N V C L F C+ V P P+ C D C
Sbjct: 1035 RKVPLDSS---PATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVDPEPYLDVCIYDTCSC 1091
Query: 307 QSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEK---------AFTYNEC 357
+S+GD A +C +A YA CAQ G+ + WRT C C+E+ + YN C
Sbjct: 1092 ESIGDCACFCDTIAAYAHVCAQHGKVVT-WRT-ATLCPQSCEERNLRENGYECEWRYNSC 1149
Query: 358 IACCPASC-HPRASCVDSEIACVDGC--YCPNGLIFED--GGCVAPAECP-CEFHGTLYP 411
C +C HP + + CV+GC +CP G I ++ CV P +CP CE G +
Sbjct: 1150 APACQVTCQHPEP--LACPVQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCEVAGRRFA 1207
Query: 412 PGSVV------KEDCNTCTCTSGKWECSTAVCP 438
G V E C C C C P
Sbjct: 1208 SGKKVTLNPSDPEHCQICHCDVVNLTCEACQEP 1240
Score = 129 bits (323), Expect = 5e-29
Identities = 101/363 (27%), Positives = 151/363 (41%), Gaps = 58/363 (15%)
Query: 422 TCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQ 481
TC C +W CP C+ + H TFDG+ + +C Y+L +++ V L
Sbjct: 1939 TCGC---RW-----TCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQD-LEVILH 1989
Query: 482 NAPCGLNQDGACVQSV-------SVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAF 534
N C C++S+ SV LH D + +T G + + PY
Sbjct: 1990 NGACSPGARQGCMKSIEVKHSALSVELHSD----MEVTVNGRL-------VSVPYVGGNM 2038
Query: 535 EIRRLSSVFLRVRTN-VGVRVLYDREGLRLYLQVDQR-WVEDTVGLCGTFNGNTQDDFLS 592
E+ ++ VR N +G + + LQ+ + + T GLCG + N +DF+
Sbjct: 2039 EVNVYGAIMHEVRFNHLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFML 2098
Query: 593 PVGVPESTPQLFGNSWKTL---SACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFA 649
G + + W C P++ L P H C VL +FA
Sbjct: 2099 RDGTVTTDWKTLVQEWTVQRPGQTCQPILEEQCLVPDSSH----------CQVLLLPLFA 2148
Query: 650 PCSAFLSPVPYFEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEA 709
C L+P ++ C++D+C Q +C +A YAHLCR +G+ VD+R CA+SC
Sbjct: 2149 ECHKVLAPATFYAICQQDSCH--QEQVCEVIASYAHLCRTNGVCVDWRTP-DFCAMSCPP 2205
Query: 710 SKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRN 769
S Y+ C C R C S +CG D EGC CPPD + CVP
Sbjct: 2206 SLVYNHCEHGCPRHCDGNVS--SCG---------DHPSEGCFCPPDKVM--LEGSCVPEE 2252
Query: 770 QCS 772
C+
Sbjct: 2253 ACT 2255
Score = 119 bits (298), Expect = 4e-26
Identities = 103/380 (27%), Positives = 149/380 (39%), Gaps = 50/380 (13%)
Query: 78 ICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAV 137
+C H+ TFDG + L+G SY L E Q + +HN + C +++
Sbjct: 1949 VCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKE---QDLEVILHNGACSPGARQGCMKSI 2005
Query: 138 SLFFVG-EQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFT------LAW 190
+ E+H EVT G V +P+V G+ + Y + H+ F
Sbjct: 2006 EVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEVNV---YGAIMHEVRFNHLGHIFTFT 2062
Query: 191 DGASAVYIKMSPELLGW-THGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQP 249
+ +++SP+ T+GLCG + + +D + G +T D V W Q P Q
Sbjct: 2063 PQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQRPGQ- 2121
Query: 250 PGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSM 309
T + CL + C+ LL P F CH ++P F A C D C
Sbjct: 2122 ---TCQPILEEQCLVPDSS-------HCQVLLLPLFAECHKVLAPATFYAICQQDSCHQ- 2170
Query: 310 GDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPR- 368
C +A YA C G + WRT C + C + YN C CP C
Sbjct: 2171 ---EQVCEVIASYAHLCRTNGVCVD-WRTP-DFCAMSC-PPSLVYNHCEHGCPRHCDGNV 2224
Query: 369 ASCVDSEIACVDGCYCPNGLIFEDGGCVAPAEC-PC--------EFHGTLYPPGSVVKED 419
+SC D +GC+CP + +G CV C C +F P +
Sbjct: 2225 SSCGDHP---SEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPD----HQP 2277
Query: 420 CNTCTCTSG-KWECSTAVCP 438
C CTC SG K C+T CP
Sbjct: 2278 CQICTCLSGRKVNCTTQPCP 2297
Score = 91.3 bits (225), Expect = 1e-17
Identities = 82/333 (24%), Positives = 119/333 (35%), Gaps = 41/333 (12%)
Query: 862 RHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG---SFQCTLHP---------- 908
R GD LP++C P Q + H C RG S + P
Sbjct: 1888 RPGDVWTLPDQCHTV----TCQPDGQTLLKSHRVNCDRGLRPSCPNSQSPVKVEETCGCR 1943
Query: 909 --CASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSSGMI-CR 965
C CT RH TFDG F G+C L ++ + VI+ N C C
Sbjct: 1944 WTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQN-KEQDLEVILHNGACSPGARQGCM 2002
Query: 966 KFISINVGNSLIVFDDD-----SGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLW 1020
K I + + D +G ++ EV+ + + HI
Sbjct: 2003 KSIEVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLGHIFTFT 2062
Query: 1021 DQRTTVHVQAGPQ-WQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDT 1079
Q +Q P+ + + GLCG D N+ + T+ + W T
Sbjct: 2063 PQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQRPGQT 2122
Query: 1080 LDP--RDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDC 1137
P + C++ C +LL +F CH V+ FY+ C D+C Q
Sbjct: 2123 CQPILEEQCLVPD------SSHCQVLLLPLFAECHKVLAPATFYAICQQDSCHQEQ---- 2172
Query: 1138 ECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDC 1170
C +++YAH C +GV VDWRTP C C
Sbjct: 2173 --VCEVIASYAHLCRTNGVCVDWRTPDFCAMSC 2203
Score = 82.8 bits (203), Expect = 4e-15
Identities = 85/360 (23%), Positives = 139/360 (38%), Gaps = 55/360 (15%)
Query: 2030 CPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDE---MLTVHVLDCKSANLG 2086
C EC C + F +FD + Y+L++ + + + + C
Sbjct: 379 CSNEECPGECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQDHSFSIVIETVQCADDR-- 436
Query: 2087 HLNWPPFCL--VMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMIL 2144
C V + + L + + + V +D Q V P+ + RI+ T + L
Sbjct: 437 ----DAVCTRSVTVRLPGLHNSLVKLKHGAGVAMDGQDVQLPLLKGDLRIQHTVTASVRL 492
Query: 2145 T-PSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAP 2203
+ D+Q+ W G ++V+ S + GLCG +G+ +D G ED
Sbjct: 493 SYGEDLQMDW-DGRGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVED--- 548
Query: 2204 FLDSWQVPSSLTSVGQ------------TRFRPDSCATTDCSPCLRMVSNRTFSACHRFV 2251
F ++W++ + + TRF ++CA ++++ TF ACHR V
Sbjct: 549 FGNAWKLHGDCQDLQKQHSDPCALNPRMTRFSEEACA---------VLTSPTFEACHRAV 599
Query: 2252 PPESFCELWIRDTKYV--------QQPCVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSD 2303
P + +R+ +Y + C AL Y A C V + WR C C
Sbjct: 600 SPLPY----LRNCRYDVCSCSDGRECLCGALASYAAACAGRGVRVAWREPGRCELNCPKG 655
Query: 2304 STYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCAC 2363
Y C T C TC+ L D E + EGC C G + R C+P+A+C C
Sbjct: 656 QVYLQCGTPCN--LTCRS--LSYPDEECNEACLEGCFCPPGLYMDERGD--CVPKAQCPC 709
Score = 79.7 bits (195), Expect = 4e-14
Identities = 108/447 (24%), Positives = 164/447 (36%), Gaps = 67/447 (14%)
Query: 1986 DCVRHICLEGQLIRVNQSQHCPQGAAPPRCGIL--------GLAVRVGGDRC-------- 2029
+C+ C+ G L +H + A RC G V++G + C
Sbjct: 798 ECMSMGCVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGETVKIGCNTCVCRDRKWN 857
Query: 2030 CPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS--PDEMLTVHVLDCKSANLGH 2087
C C CS ++TFDG E Y+L Q T +L N G
Sbjct: 858 CTDHVCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRIL---VGNKGC 914
Query: 2088 LNWPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPS 2147
+ P +T L I+ F+ +V V P F + ++G ++L
Sbjct: 915 SH--PSVKCKKRVTILVEGGEIELFDGEVNVKR----PMKDETHFEVVESGRYIILLLGK 968
Query: 2148 DIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDS 2207
+ + W + +V +T + + GLCG DG NDLT + V EDP F +S
Sbjct: 969 ALSVVWDRHLSISVV-LKQTYQEKVCGLCGNFDGIQNNDLTSSNLQV---EEDPVDFGNS 1024
Query: 2208 WQVPSSLTSVGQTRF--RPDSCAT-----TDCSPCLRMVSNRTFSACHRFVPPESFCELW 2260
W+V S + P +C T R++++ F C++ V PE + ++
Sbjct: 1025 WKVSSQCADTRKVPLDSSPATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVDPEPYLDVC 1084
Query: 2261 IRDTKYVQQP------CVALTVYVAMCHKFHVCIEWRRSDYCPFLCSS----------DS 2304
I DT + C + Y +C + + WR + CP C +
Sbjct: 1085 IYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVVTWRTATLCPQSCEERNLRENGYECEW 1144
Query: 2305 TYQACVTACEPPKTCQDGILGPLDPEHCQV-LGEGC--VCSEGTILHRRHSALCIPEAKC 2361
Y +C AC+ TCQ +P C V EGC C G IL C+ C
Sbjct: 1145 RYNSCAPACQ--VTCQHP-----EPLACPVQCVEGCHAHCPPGKILDELLQT-CVDPEDC 1196
Query: 2362 ACTDSMGVPRALGE--TWNSSLSGCCQ 2386
+ G A G+ T N S CQ
Sbjct: 1197 PVCEVAGRRFASGKKVTLNPSDPEHCQ 1223
Score = 74.7 bits (182), Expect = 1e-12
Identities = 89/366 (24%), Positives = 137/366 (37%), Gaps = 38/366 (10%)
Query: 2017 ILGLAVRVGGDRCCPLWE---CACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEML 2073
+L LA+ + G C RCS+F TFDGS + Y+L+ +
Sbjct: 10 LLALALILPGTLCAEGTRGRSSTARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRS 69
Query: 2074 TVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRF-NRKVTVDLQPVWPPVSRYGF 2132
+ D ++ L+ +L I F N VT Q V P + G
Sbjct: 70 FSIIGDFQNGKRVSLS-----------VYLGEFFDIHLFVNGTVTQGDQRVSMPYASKGL 118
Query: 2133 RIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDG 2192
+E Y + + + + SG V S + GLCG + A +D ++G
Sbjct: 119 YLETEAGYYKLSGEAYGFVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEG 178
Query: 2193 SVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTD-------CSPCLRMVSNRTFS 2245
++ DP F +SW + S + SC + C + S F+
Sbjct: 179 TLTS---DPYDFANSWALSSGEQWCERASPPSSSCNISSGEMQKGLWEQCQLLKSTSVFA 235
Query: 2246 ACHRFVPPESF---CELWIRD-TKYVQQPCVALTVYVAMC-HKFHVCIEWRRSDYCPFLC 2300
CH V PE F CE + + ++ C AL Y C + V W C +C
Sbjct: 236 RCHPLVDPEPFVALCEKTLCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVC 295
Query: 2301 SSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAK 2360
+ Y+ CV+ C +TCQ + + E C +GC C EG +L LC+ +
Sbjct: 296 PAGMEYRQCVSPC--ARTCQSLHINEMCQERCV---DGCSCPEGQLL---DEGLCVESTE 347
Query: 2361 CACTDS 2366
C C S
Sbjct: 348 CPCVHS 353
Score = 62.4 bits (150), Expect = 6e-09
Identities = 28/56 (50%), Positives = 35/56 (62%), Gaps = 1/56 (1%)
Query: 1336 CEWRYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCPTPQVLDEVTQRCVYLEDC 1391
CEWRY++CA C TC+ P +C V VEGC CP ++LDE+ Q CV EDC
Sbjct: 1142 CEWRYNSCAPACQVTCQHPEPLAC-PVQCVEGCHAHCPPGKILDELLQTCVDPEDC 1196
Score = 45.4 bits (106), Expect = 8e-04
Identities = 53/200 (26%), Positives = 73/200 (36%), Gaps = 50/200 (25%)
Query: 331 RPLQGWRTQLRQC----TVHCKEKAFTYNECIACCPASCHP-------RASCVDSEIACV 379
R LQ T +C T C+++ EC P SC P + C D E C
Sbjct: 2342 RGLQPTLTNPGECRPNFTCACRKE-----ECKRVSPPSCPPHRLPTLRKTQCCD-EYECA 2395
Query: 380 DGCY-----CPNGLIFE----DGGCVAPAECP---CEFHGTLYPPGSVVKEDCNTCTCTS 427
C CP G + D GC P C T+YP G +E C+ CTCT
Sbjct: 2396 CNCVNSTVSCPLGYLASTATNDCGCTTTTCLPDKVCVHRSTIYPVGQFWEEGCDVCTCTD 2455
Query: 428 GK--------WECSTAVCPAEC--SVTGDIHFTTFDGRRYTFPATCQYILAKSR------ 471
+ +CS C C T +H GR P+ C+ + R
Sbjct: 2456 MEDAVMGLRVAQCSQKPCEDSCRSGFTYVLHEGECCGR--CLPSACEVVTGSPRGDSQSS 2513
Query: 472 --SSGTFTVTLQNAPCGLNQ 489
S G+ + +N PC +N+
Sbjct: 2514 WKSVGSQWASPEN-PCLINE 2532
Score = 34.7 bits (78), Expect = 1.4
Identities = 22/63 (34%), Positives = 28/63 (44%), Gaps = 6/63 (9%)
Query: 1331 AAYPICE--WRYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCPTPQVLDEVTQRCVYL 1388
A P+C Y C SPC +TC+ V+GC CP Q+LDE CV
Sbjct: 290 ACSPVCPAGMEYRQCVSPCARTCQSLHINEMCQERCVDGC--SCPEGQLLDE--GLCVES 345
Query: 1389 EDC 1391
+C
Sbjct: 346 TEC 348
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 615 bits (1585), Expect = e-175
Identities = 362/1124 (32%), Positives = 557/1124 (49%), Gaps = 59/1124 (5%)
Query: 77 SICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRA 136
++C WG H +TFDG + G Y + F++ + P +P
Sbjct: 35 NVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQAEAPAGVESI 94
Query: 137 VSLFFVGEQEIHLAKEVTH-GGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASA 195
L + + I+L + + G V PH +++ Y V ++ TL W+ A
Sbjct: 95 --LLTIKDDTIYLTRHLAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLTLMWNREDA 152
Query: 196 VYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTS 255
+ +++ + T GLCG+ N S G L + EF + Q NQP
Sbjct: 153 LMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPL-EFGNM---QKINQP-----D 203
Query: 256 SLPRPPCLQQNPGTMQGVYEQCEALLRPP-FDACHAYVSPLPFTASCTSDLCQSMGDVAT 314
+ P + P + +CE LL F C V P+ +C D C+ G
Sbjct: 204 VVCEDPEEEVAPASCSEHRAECERLLTAEAFADCQDLVPLEPYLRACQQDRCRCPGGDTC 263
Query: 315 WCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDS 374
C +AE++R C+ AG WRT C C C H S +
Sbjct: 264 VCSTVAEFSRQCSHAGGRPGNWRTATL-CPKTCPGNLVYLESGSPCMDTCSHLEVSSLCE 322
Query: 375 EIACVDGCYCPNGLIFED---GGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWE 431
E +DGC+CP G +++D GCV ++C C HG LY PG + DC C C +G+W
Sbjct: 323 EHR-MDGCFCPEGTVYDDIGDSGCVPVSQCHCRLHGHLYTPGQEITNDCEQCVCNAGRWV 381
Query: 432 CSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDG 491
C CP C++ G H TTFDG+ YTF C Y+LAK + ++ + + APCG
Sbjct: 382 CKDLPCPGTCALEGGSHITTFDGKTYTFHGDCYYVLAKGDHNDSYALLGELAPCGSTDKQ 441
Query: 492 ACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVG 551
C+++V +L D ++ V + ++ +L ++ ++ P+ +F + R SS + V +G
Sbjct: 442 TCLKTV--VLLADKKKNVVVFKSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVSMAIG 499
Query: 552 VRVLYDREG-LRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKT 610
VR+ ++L++ +DQ GLCG FNG DDF + G+ E+T F N+WK
Sbjct: 500 VRLQVQLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKA 559
Query: 611 LSACSPLVSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDA 668
S+C + DPC +++++A+Y+ CS+L T F C + + P Y+++C+ D
Sbjct: 560 QSSCHDKLDWLD-DPCSLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDT 618
Query: 669 CRC--GQPCLCATLAHYAHLCRRHGLPVDFRARLPACAL---SCEASKEYSPCVAPCGRT 723
C C + CLCA L+ YA C G+ + + R C SC S+ + + C +T
Sbjct: 619 CNCQNNEDCLCAALSSYARACTAKGVML-WGWREHVCNKDVGSCPNSQVFLYNLTTCQQT 677
Query: 724 CQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPG 783
C+ L+ ++ ++G V+GC CP T+LD + CVP +CSC+ +G+ G
Sbjct: 678 CRSLSEADSHCLEGFAP------VDGCGCPDHTFLDEKGR-CVPLAKCSCYHRGLYLEAG 730
Query: 784 DSDIPSLGHCHCKDGVMSCDS-RAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNL 842
D + C C+DG + C R +C A ++ ++CS+L T L S+ R Q L
Sbjct: 731 DVVVRQEERCVCRDGRLHCRQIRLIGQSCTAPKIHMDCSNL-TALATSKPRALSCQTLAA 789
Query: 843 SVSARGPCLSGCACPQGLLRHG-DACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGS 901
C+SGC CP GL+ G C + +ECPC Y G ++ C+TC C+RG
Sbjct: 790 GYY-HTECVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGR 848
Query: 902 FQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVK-----STSDVSFSVIVENVN 956
+ CT C TC+ YG HY TFDG +DF G C V+ ++S SFS+I ENV
Sbjct: 849 WVCTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVP 908
Query: 957 CYSSGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVH-----TWRVGFFTLVHF 1011
C ++G+ C K I I +G + + +D + + E H T VG + +V
Sbjct: 909 CGTTGVTCSKAIKIFMGRTELKLEDK------HRVVIQRDEGHHVAYTTREVGQYLVVE- 961
Query: 1012 PQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSW 1071
I ++WD+RTTV ++ P ++G + GLCGNFD ++ N+ T +++ +++ +FG+SW
Sbjct: 962 SSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSW 1021
Query: 1072 A-AVECPDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCG 1130
A CPD + C LNP R +A+K+CSIL S VF ICH VD FY C+ D+C
Sbjct: 1022 KEAPTCPDVSTNPEPCSLNPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCS 1081
Query: 1131 CSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFN 1174
C GGDCECFC++V++YA +C + G V WRTP LCP CD++N
Sbjct: 1082 CDTGGDCECFCSAVASYAQECTKEGACVFWRTPDLCPIFCDYYN 1125
Score = 250 bits (639), Expect = 1e-65
Identities = 228/921 (24%), Positives = 364/921 (39%), Gaps = 187/921 (20%)
Query: 25 ERRLHRAKCAPSYLFSCFNGGECVHPAFCDCRRFN--------ATGPRCQMVYNAGP--- 73
E R+ C ++ CV + C CR T Q V NAG
Sbjct: 323 EHRMDGCFCPEGTVYDDIGDSGCVPVSQCHCRLHGHLYTPGQEITNDCEQCVCNAGRWVC 382
Query: 74 ---ERDSICRAWGQHHVETFDGLYYYLSGKGSYTLV-GRHEPEGQSFSIQVHNDPQCGSS 129
C G H+ TFDG Y G Y L G H S+++ P CGS+
Sbjct: 383 KDLPCPGTCALEGGSHITTFDGKTYTFHGDCYYVLAKGDHN---DSYALLGELAP-CGST 438
Query: 130 P-YTCSRAVSLFFVGEQEIHLAKE---VTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSA 185
TC + V L ++ + + K V ++V LPHV S + + + Y I+ +
Sbjct: 439 DKQTCLKTVVLLADKKKNVVVFKSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVSMAI 498
Query: 186 ---FTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ 242
+ +++ + G GLCGN N DD T+SG + F ++W+
Sbjct: 499 GVRLQVQLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWK 558
Query: 243 EQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRP--PFDACHAYVSPLPF--- 297
Q+ PC N + C L + PF CH+ V P +
Sbjct: 559 AQSSCHDKLDWLDD----PC-SLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKR 613
Query: 298 ----TASCTSD---LCQSMGD---------VATW-------------------------- 315
T +C ++ LC ++ V W
Sbjct: 614 CKYDTCNCQNNEDCLCAALSSYARACTAKGVMLWGWREHVCNKDVGSCPNSQVFLYNLTT 673
Query: 316 ----CRALAEYARACAQAGRPLQGW----------------------------------- 336
CR+L+E C + P+ G
Sbjct: 674 CQQTCRSLSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVV 733
Query: 337 -----RTQLRQCTVHCKEKAFTYNECIA----------CCPASCHPRASCVDSEIA---- 377
R R +HC++ C A A+ PRA + A
Sbjct: 734 VRQEERCVCRDGRLHCRQIRLIGQSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYH 793
Query: 378 --CVDGCYCPNGLIFED-GGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWECST 434
CV GC CP+GL+ + GGCV ECPC + LY G+ +K DCNTCTC G+W C+
Sbjct: 794 TECVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQ 853
Query: 435 AVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAK-----SRSSGTFTVTLQNAPCGLNQ 489
AVC CS+ G H+ TFDG+ Y F C Y+ + + S G+F++ +N PCG
Sbjct: 854 AVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTT- 912
Query: 490 DGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDD---AFEIRRLSSVFLRV 546
C +++ + + + ++ L D+++++ + A+ R + +L V
Sbjct: 913 GVTCSKAIKIFMGRT-----------ELKLEDKHRVVIQRDEGHHVAYTTREVGQ-YLVV 960
Query: 547 RTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGN 606
++ G+ V++D+ +++++ + GLCG F+ + +DF + + S+ FGN
Sbjct: 961 ESSTGIIVIWDKR-TTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGN 1019
Query: 607 SWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRR 666
SWK C P VS +P +PC ++ S++ + CS+L +F+ C + + P P++E C
Sbjct: 1020 SWKEAPTC-PDVSTNP-EPCSLNPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVH 1077
Query: 667 DACRCGQ----PCLCATLAHYAHLCRRHGLPVDFRARLPACALSC-------EASKEYSP 715
D+C C C C+ +A YA C + G V +R C + C E Y P
Sbjct: 1078 DSCSCDTGGDCECFCSAVASYAQECTKEGACVFWRTP-DLCPIFCDYYNPPHECEWHYEP 1136
Query: 716 CVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGC--ACPPDTYL-DTQADLCVPRNQCS 772
C TC+ + G+ +S +EGC CP D + + CV ++C
Sbjct: 1137 CGNRSFETCRTIN-----GIHSNISVSY---LEGCYPRCPKDRPIYEEDLKKCVTADKCG 1188
Query: 773 CHFQGVDYPPGDSDIPSLGHC 793
C+ + YPPG S +P+ C
Sbjct: 1189 CYVEDTHYPPGAS-VPTEETC 1208
Score = 248 bits (632), Expect = 8e-65
Identities = 316/1346 (23%), Positives = 474/1346 (35%), Gaps = 216/1346 (16%)
Query: 1415 PTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNP-PVTATEEPVVSPGPTQTTLQQPL 1473
PTP+ + + T T P TP T P T T P +P TQT P+
Sbjct: 3797 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3856
Query: 1474 ELTASQLPAGP---TESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRV 1530
T + P T++P + +T + P TP P QTPT + TT
Sbjct: 3857 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPT----PTGTQTPTTTPI-----TTTT 3906
Query: 1531 TVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGS---LPVRTTP-----PQPSLTASP 1582
TV +P T + + P +T T G + P+ TT P P+ T +P
Sbjct: 3907 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3966
Query: 1583 SSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTA 1642
++ P+ + ++ +PT +G+ TP T + T P PT + + +TP+T T
Sbjct: 3967 TTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTV 4023
Query: 1643 AE-------QVPVS-PLATRSLEIVLSTEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQ 1693
Q P + P+ T + T G + + P+ + + P P P+ P
Sbjct: 4024 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 4083
Query: 1694 HTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVG 1753
T + T + P TP T T TP + + P+ +G T+ P+
Sbjct: 4084 -TPITTTTTVTPTPTP------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 4136
Query: 1754 TSAPVATPGPKASVITTPLQPQAT--------------TLPAQTLSPVLPFTPAAMTQAH 1799
T P TP + TTP+ T T P T + V P TQ
Sbjct: 4137 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTG 4196
Query: 1800 PPTHIA-----------PPAAGTAPGLLLGATLP---TSGVLPVAEGTASMVSVVPRKST 1845
PPTH + PP + P + P ++ +L M S P +
Sbjct: 4197 PPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTP 4256
Query: 1846 TGKVAILSKQ-VSLPTSMYGSAEGGPTE-LTPATSHPLTPLVAEPEGAQAGTALPVPTSY 1903
T +S P S S G PT T +S TP + A T P P S
Sbjct: 4257 TAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLST 4316
Query: 1904 ALSRVSARTAPQDSMLVLLPQLAEAH---------GTSAGPHLAAEPVDEATTEPSGRSA 1954
+ P S +++ L + + GT T E S
Sbjct: 4317 PSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSC 4376
Query: 1955 PALSIVEGLAEALATTTEANTSTTCVPIAEQ---------------------DCVRHICL 1993
P+ T +ST P DC C
Sbjct: 4377 PSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECPDFDPPRQENETWWLCDCFMATCK 4436
Query: 1994 EGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGG-DRCCPLWECACRCSIFPDLSFVTFDG 2052
+ + + + P P C VRV D CC WEC C C+ + D +VTFDG
Sbjct: 4437 YNNTVEIVKVECEPPPM--PTCSNGLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDG 4494
Query: 2053 SHVALFKEAIYILSQ--SPDEMLTVHVLDCKSANLGHLNWPP----FCLVMLNMTHLAHQ 2106
+ + Y+L + SP +D + + + P C L + H +
Sbjct: 4495 LYYSYQGNCTYVLVEEISPS-------VDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQE 4547
Query: 2107 VTIDRFNR-----KVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMI 2161
V I + +V V+ Q V P +YG + +G Y++ P + + +
Sbjct: 4548 VLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVLVSYNGLSFSV 4607
Query: 2162 VEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVP---------S 2212
G CG C ++D L G +V E A D W V S
Sbjct: 4608 RLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAA---DQWLVNDPSKPHCPHS 4664
Query: 2213 SLTSVGQTRFRPDSCATT---DC--SPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYV 2267
S T+ P TT DC SP +++ + F+ CH VPP+ + + + D+ ++
Sbjct: 4665 SSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSCFM 4724
Query: 2268 ---QQPCVALTVYVAMCHKFHVCIEWRRSDY--CPFLCSSDSTYQACVTACEPPKTCQDG 2322
C +L Y A+C + ++C++WR + C C S YQAC A EP TC+
Sbjct: 4725 PGSSLECASLQAYAALCAQQNICLDWRNHTHGACLVECPSHREYQACGPAEEP--TCKSS 4782
Query: 2323 ILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLS 2382
++ VL EGC C EGT+ + +C+ C C VPR GE +
Sbjct: 4783 S----SQQNNTVLVEGCFCPEGTMNYAPGFDVCVKT--CGCVGPDNVPREFGEHFEFDCK 4836
Query: 2383 GCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGE-VALLLPTKDPCCLGTVCVCNQTLCEG 2441
C + I+ C C+ G +A + D CC TVC CN +LC+
Sbjct: 4837 NCVC--LEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTCCNITVCKCNTSLCKE 4894
Query: 2442 LAPTCRPGHRLLTHFQEDSCCPSYSCECDPDLC---EAELVPSCRQDQILITGRLGDSCC 2498
C G + + CCP Y CE +C AE P
Sbjct: 4895 KPSVCPLGFEVKSKMVPGRCCPFYWCE-SKGVCVHGNAEYQPG----------------S 4937
Query: 2499 TSYFCACGDCPDSIPECQEGEALTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEV 2558
Y C DC C + V NT L C + C C G L+E
Sbjct: 4938 PVYSSKCQDC-----VCTD----KVDNNTL-----LNVIACTHVPC-NTSCSPGFELME- 4981
Query: 2559 WSPDRCCPYKSCE---C---------------DCDTIPVPRCHLWEKSQLDEEFMHSVEN 2600
+P CC K CE C D + P C + ++ + + SV N
Sbjct: 4982 -APGECC--KKCEQTHCIIKRPDNQHVILKPGDFKSDPKNNCTFFSCVKIHNQLISSVSN 5038
Query: 2601 VCGCAKYECVKAPVCLSRELGVMQPG 2626
+ C ++ A +C+ + M G
Sbjct: 5039 IT-CPNFD---ASICIPGSITFMPNG 5060
Score = 157 bits (398), Expect = 1e-37
Identities = 125/396 (31%), Positives = 180/396 (45%), Gaps = 40/396 (10%)
Query: 79 CRAWGQHHVETFDGLYYYLSGKGSYTLV----GRHEPEGQSFSIQVHNDPQCGSSPYTCS 134
C +G H TFDG YY G SY V G++ G SFSI N P CG++ TCS
Sbjct: 860 CSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLG-SFSIITENVP-CGTTGVTCS 917
Query: 135 RAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGAS 194
+A+ +F +G E+ L + R + HV + R ++ Y++V + + WD +
Sbjct: 918 KAIKIF-MGRTELKLEDKHRVVIQRDEGHHVAYTTR--EVGQYLVVESSTGIIVIWDKRT 974
Query: 195 AVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTT 254
V+IK++P G GLCGN + +D T + ++F +SW+E P P
Sbjct: 975 TVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEA----PTCPDV 1030
Query: 255 SSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQ--SMGDV 312
S+ P P L NP +QC L F CH+ V P PF +C D C + GD
Sbjct: 1031 STNPEPCSL--NPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDC 1088
Query: 313 ATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCK------EKAFTYNECIACCPASCH 366
+C A+A YA+ C + G + WRT C + C E + Y C +C
Sbjct: 1089 ECFCSAVASYAQECTKEGACVF-WRTP-DLCPIFCDYYNPPHECEWHYEPCGNRSFETCR 1146
Query: 367 PRASCVDS-EIACVDGCY--CPNGL-IFEDG--GCVAPAECPCEFHGTLYPPGSVV--KE 418
+ ++ ++GCY CP I+E+ CV +C C T YPPG+ V +E
Sbjct: 1147 TINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGASVPTEE 1206
Query: 419 DCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDG 454
C +C CT+ S VC E G I T DG
Sbjct: 1207 TCKSCVCTNS----SQVVCRPE---EGKILNQTQDG 1235
Score = 125 bits (313), Expect = 8e-28
Identities = 141/630 (22%), Positives = 223/630 (35%), Gaps = 66/630 (10%)
Query: 1380 EVTQRCVYLEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALT 1439
E+ +C +CV + T N T P + + T + P + +TPT T
Sbjct: 1870 EINVQCC---ECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPT----TT 1922
Query: 1440 PAAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLA 1499
P TT VT T P + PT T + +T + P G T++P + +T +
Sbjct: 1923 PITTTTT-----VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-TQTPTTTPITTTTTV 1976
Query: 1500 IPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAV 1559
P TP P QTPT + TT TV +P T + + P +T
Sbjct: 1977 TP-TP----TPTGTQTPTTTPI-----TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2026
Query: 1560 TVRG---HGSLPVRTT-----PPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAV 1611
T G + P+ TT P P+ T +P++ P+ + ++ +PT +G+ TP
Sbjct: 2027 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2086
Query: 1612 TKVISRTGVPQPTQAQSASSPSTPLTVAGT-------AAEQVP-VSPLATRSLEIVLSTE 1663
T + T P PT + + +TP+T T Q P +P+ T + T
Sbjct: 2087 T---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2143
Query: 1664 KG-EAGHSQPMGSPASPQPHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLA 1722
G + + P+ + + P P P+ P T + T + P TP T T
Sbjct: 2144 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTPTP------TGTQTPT 2196
Query: 1723 ATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLP-- 1780
TP + + P+ +G T+ P+ T P TP + TTP+ T P
Sbjct: 2197 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2256
Query: 1781 ------AQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTA 1834
T +P+ T T T T + PT P
Sbjct: 2257 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2316
Query: 1835 SMVSVVPRKSTTGKVAILSKQVSLPTSMYGSAEGGPTE---LTPATSHPLTPLVAEPEGA 1891
+ +V P + TG + ++ T++ + T+ TP T+ P G
Sbjct: 2317 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2376
Query: 1892 QAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLAEAHGTSAGPHLAAEPVDEATTEPSG 1951
Q T P+ T+ ++ T Q + T+ P TT P
Sbjct: 2377 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT-----TTVTPTPTPTGTQTPTTTPIT 2431
Query: 1952 RSAPALSIVEGLAEALATTTEANTSTTCVP 1981
+ TTT T+TT P
Sbjct: 2432 TTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2461
Score = 124 bits (310), Expect = 2e-27
Identities = 140/590 (23%), Positives = 213/590 (36%), Gaps = 58/590 (9%)
Query: 1415 PTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNP-PVTATEEPVVSPGPTQTTLQQPL 1473
PTP+ + + T T P TP T P T T P +P TQT P+
Sbjct: 3705 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3764
Query: 1474 ELTASQLPAGP---TESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRV 1530
T + P T++P + +T + P TP P QTPT + TT
Sbjct: 3765 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPT----PTGTQTPTTTPI-----TTTT 3814
Query: 1531 TVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGS---LPVRTTP-----PQPSLTASP 1582
TV +P T + + P +T T G + P+ TT P P+ T +P
Sbjct: 3815 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3874
Query: 1583 SSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTA 1642
++ P+ + ++ +PT +G+ TP T + T P PT + + +TP+T T
Sbjct: 3875 TTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTV 3931
Query: 1643 AE-------QVPVS-PLATRSLEIVLSTEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQ 1693
Q P + P+ T + T G + + P+ + + P P P+ P
Sbjct: 3932 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3991
Query: 1694 HTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVG 1753
T + T + P TP T T TP + + P+ +G T+ P+
Sbjct: 3992 -TPITTTTTVTPTPTP------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 4044
Query: 1754 TSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAP 1813
T P TP + TTP+ T P T + T +T T P P
Sbjct: 4045 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 4104
Query: 1814 GLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGSAEGGPTEL 1873
T T P GT + TT + + PT G+ T +
Sbjct: 4105 TTTPITTTTTVTPTPTPTGT--------QTPTTTPITTTTTVTPTPTPT-GTQTPTTTPI 4155
Query: 1874 TPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDS--MLVLLPQLAEAHGT 1931
T T+ TP P G Q T P+ T+ ++ T Q +AE +
Sbjct: 4156 TTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTS 4212
Query: 1932 SAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 1981
+ P + +T+ P S LS L A+ T+ A ST P
Sbjct: 4213 NPPPESSTPQTSRSTSSPLTESTTLLST---LPPAIEMTSTAPPSTPTAP 4259
Score = 123 bits (308), Expect = 3e-27
Identities = 142/643 (22%), Positives = 220/643 (34%), Gaps = 62/643 (9%)
Query: 1373 PTPQVLDEVTQRCVYLEDCVEPAVWVPTEA--LGNETLPPSQGLPTPSDEEPQLSQESPR 1430
PTP +T PT T+ P+ PTP+ + +
Sbjct: 1893 PTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITT 1949
Query: 1431 TPTHRPALTPAAPLTTALNP-PVTATEEPVVSPGPTQTTLQQPLELTASQLPAGP---TE 1486
T T P TP T P T T P +P TQT P+ T + P T+
Sbjct: 1950 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2009
Query: 1487 SPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRS 1546
+P + +T + P TP P QTPT + TT TV +P T + +
Sbjct: 2010 TPTTTPITTTTTVTP-TPT----PTGTQTPTTTPI-----TTTTTVTPTPTPTGTQTPTT 2059
Query: 1547 PPAPRFPLMTKAVTVRGHGS---LPVRTTP-----PQPSLTASPSSRPVASPGAISRSPT 1598
P +T T G + P+ TT P P+ T +P++ P+ + ++ +PT
Sbjct: 2060 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2119
Query: 1599 SSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTAAE-------QVPVS-P 1650
+G+ TP T + T P PT + + +TP+T T Q P + P
Sbjct: 2120 PTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2176
Query: 1651 LATRSLEIVLSTEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQHTTMATRSPALPPETP 1709
+ T + T G + + P+ + + P P P+ P T + T + P TP
Sbjct: 2177 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTPTP 2235
Query: 1710 AAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAPVATPGPKASVIT 1769
T T TP + + P+ +G T+ P+ T P TP + T
Sbjct: 2236 ------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2289
Query: 1770 TPLQPQATTLP--------AQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATL 1821
TP+ T P T +P+ T T T T +
Sbjct: 2290 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2349
Query: 1822 PTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGSAEGGPTE---LTPATS 1878
PT P + +V P + TG + ++ T++ + T+ TP T+
Sbjct: 2350 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2409
Query: 1879 HPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLAEAHGTSAGPHLA 1938
P G Q T P+ T+ ++ T Q + T+ P
Sbjct: 2410 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT-----TTVTPTPT 2464
Query: 1939 AEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 1981
TT P + TTT T+TT P
Sbjct: 2465 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2507
Score = 122 bits (306), Expect = 5e-27
Identities = 134/599 (22%), Positives = 209/599 (34%), Gaps = 57/599 (9%)
Query: 1415 PTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNP-PVTATEEPVVSPGPTQTTLQQPL 1473
PTP+ + + T T P TP T P T T P +P TQT P+
Sbjct: 2095 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2154
Query: 1474 ELTASQLPAGP---TESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRV 1530
T + P T++P + +T + P TP P QTPT + TT
Sbjct: 2155 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPT----PTGTQTPTTTPI-----TTTT 2204
Query: 1531 TVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGS---LPVRTTP-----PQPSLTASP 1582
TV +P T + + P +T T G + P+ TT P P+ T +P
Sbjct: 2205 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2264
Query: 1583 SSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTA 1642
++ P+ + ++ +PT +G+ TP T + T P PT + + +TP+T T
Sbjct: 2265 TTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTV 2321
Query: 1643 AE-------QVPVS-PLATRSLEIVLSTEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQ 1693
Q P + P+ T + T G + + P+ + + P P P+ P
Sbjct: 2322 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2381
Query: 1694 HTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVG 1753
T + T + P TP T T TP + + P+ +G T+ P+
Sbjct: 2382 -TPITTTTTVTPTPTP------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2434
Query: 1754 TSAPVATPGPKASVITTPLQPQATTLP--------AQTLSPVLPFTPAAMTQAHPPTHIA 1805
T P TP + TTP+ T P T +P+ T T T
Sbjct: 2435 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2494
Query: 1806 PPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGS 1865
T + PT P + +V P + TG + ++ T++ +
Sbjct: 2495 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2554
Query: 1866 AEGGPTE---LTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLL 1922
T+ TP T+ P G Q T P+ T+ ++ T Q +
Sbjct: 2555 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2614
Query: 1923 PQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 1981
T+ P TT P + TTT T+TT P
Sbjct: 2615 TTT-----TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2668
Score = 122 bits (306), Expect = 5e-27
Identities = 134/599 (22%), Positives = 209/599 (34%), Gaps = 57/599 (9%)
Query: 1415 PTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNP-PVTATEEPVVSPGPTQTTLQQPL 1473
PTP+ + + T T P TP T P T T P +P TQT P+
Sbjct: 2256 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2315
Query: 1474 ELTASQLPAGP---TESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRV 1530
T + P T++P + +T + P TP P QTPT + TT
Sbjct: 2316 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPT----PTGTQTPTTTPI-----TTTT 2365
Query: 1531 TVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGS---LPVRTTP-----PQPSLTASP 1582
TV +P T + + P +T T G + P+ TT P P+ T +P
Sbjct: 2366 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2425
Query: 1583 SSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTA 1642
++ P+ + ++ +PT +G+ TP T + T P PT + + +TP+T T
Sbjct: 2426 TTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTV 2482
Query: 1643 AE-------QVPVS-PLATRSLEIVLSTEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQ 1693
Q P + P+ T + T G + + P+ + + P P P+ P
Sbjct: 2483 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2542
Query: 1694 HTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVG 1753
T + T + P TP T T TP + + P+ +G T+ P+
Sbjct: 2543 -TPITTTTTVTPTPTP------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2595
Query: 1754 TSAPVATPGPKASVITTPLQPQATTLP--------AQTLSPVLPFTPAAMTQAHPPTHIA 1805
T P TP + TTP+ T P T +P+ T T T
Sbjct: 2596 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2655
Query: 1806 PPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGS 1865
T + PT P + +V P + TG + ++ T++ +
Sbjct: 2656 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2715
Query: 1866 AEGGPTE---LTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLL 1922
T+ TP T+ P G Q T P+ T+ ++ T Q +
Sbjct: 2716 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2775
Query: 1923 PQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 1981
T+ P TT P + TTT T+TT P
Sbjct: 2776 TTT-----TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2829
Score = 122 bits (306), Expect = 5e-27
Identities = 134/599 (22%), Positives = 209/599 (34%), Gaps = 57/599 (9%)
Query: 1415 PTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNP-PVTATEEPVVSPGPTQTTLQQPL 1473
PTP+ + + T T P TP T P T T P +P TQT P+
Sbjct: 2417 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2476
Query: 1474 ELTASQLPAGP---TESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRV 1530
T + P T++P + +T + P TP P QTPT + TT
Sbjct: 2477 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPT----PTGTQTPTTTPI-----TTTT 2526
Query: 1531 TVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGS---LPVRTTP-----PQPSLTASP 1582
TV +P T + + P +T T G + P+ TT P P+ T +P
Sbjct: 2527 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2586
Query: 1583 SSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTA 1642
++ P+ + ++ +PT +G+ TP T + T P PT + + +TP+T T
Sbjct: 2587 TTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTV 2643
Query: 1643 AE-------QVPVS-PLATRSLEIVLSTEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQ 1693
Q P + P+ T + T G + + P+ + + P P P+ P
Sbjct: 2644 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2703
Query: 1694 HTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVG 1753
T + T + P TP T T TP + + P+ +G T+ P+
Sbjct: 2704 -TPITTTTTVTPTPTP------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2756
Query: 1754 TSAPVATPGPKASVITTPLQPQATTLP--------AQTLSPVLPFTPAAMTQAHPPTHIA 1805
T P TP + TTP+ T P T +P+ T T T
Sbjct: 2757 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2816
Query: 1806 PPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGS 1865
T + PT P + +V P + TG + ++ T++ +
Sbjct: 2817 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2876
Query: 1866 AEGGPTE---LTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLL 1922
T+ TP T+ P G Q T P+ T+ ++ T Q +
Sbjct: 2877 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2936
Query: 1923 PQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 1981
T+ P TT P + TTT T+TT P
Sbjct: 2937 TTT-----TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2990
Score = 122 bits (306), Expect = 5e-27
Identities = 134/599 (22%), Positives = 209/599 (34%), Gaps = 57/599 (9%)
Query: 1415 PTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNP-PVTATEEPVVSPGPTQTTLQQPL 1473
PTP+ + + T T P TP T P T T P +P TQT P+
Sbjct: 2578 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2637
Query: 1474 ELTASQLPAGP---TESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRV 1530
T + P T++P + +T + P TP P QTPT + TT
Sbjct: 2638 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPT----PTGTQTPTTTPI-----TTTT 2687
Query: 1531 TVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGS---LPVRTTP-----PQPSLTASP 1582
TV +P T + + P +T T G + P+ TT P P+ T +P
Sbjct: 2688 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2747
Query: 1583 SSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTA 1642
++ P+ + ++ +PT +G+ TP T + T P PT + + +TP+T T
Sbjct: 2748 TTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTV 2804
Query: 1643 AE-------QVPVS-PLATRSLEIVLSTEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQ 1693
Q P + P+ T + T G + + P+ + + P P P+ P
Sbjct: 2805 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2864
Query: 1694 HTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVG 1753
T + T + P TP T T TP + + P+ +G T+ P+
Sbjct: 2865 -TPITTTTTVTPTPTP------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2917
Query: 1754 TSAPVATPGPKASVITTPLQPQATTLP--------AQTLSPVLPFTPAAMTQAHPPTHIA 1805
T P TP + TTP+ T P T +P+ T T T
Sbjct: 2918 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2977
Query: 1806 PPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGS 1865
T + PT P + +V P + TG + ++ T++ +
Sbjct: 2978 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3037
Query: 1866 AEGGPTE---LTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLL 1922
T+ TP T+ P G Q T P+ T+ ++ T Q +
Sbjct: 3038 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3097
Query: 1923 PQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 1981
T+ P TT P + TTT T+TT P
Sbjct: 3098 TTT-----TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3151
Score = 122 bits (306), Expect = 5e-27
Identities = 134/599 (22%), Positives = 209/599 (34%), Gaps = 57/599 (9%)
Query: 1415 PTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNP-PVTATEEPVVSPGPTQTTLQQPL 1473
PTP+ + + T T P TP T P T T P +P TQT P+
Sbjct: 2739 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2798
Query: 1474 ELTASQLPAGP---TESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRV 1530
T + P T++P + +T + P TP P QTPT + TT
Sbjct: 2799 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPT----PTGTQTPTTTPI-----TTTT 2848
Query: 1531 TVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGS---LPVRTTP-----PQPSLTASP 1582
TV +P T + + P +T T G + P+ TT P P+ T +P
Sbjct: 2849 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2908
Query: 1583 SSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTA 1642
++ P+ + ++ +PT +G+ TP T + T P PT + + +TP+T T
Sbjct: 2909 TTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTV 2965
Query: 1643 AE-------QVPVS-PLATRSLEIVLSTEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQ 1693
Q P + P+ T + T G + + P+ + + P P P+ P
Sbjct: 2966 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3025
Query: 1694 HTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVG 1753
T + T + P TP T T TP + + P+ +G T+ P+
Sbjct: 3026 -TPITTTTTVTPTPTP------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3078
Query: 1754 TSAPVATPGPKASVITTPLQPQATTLP--------AQTLSPVLPFTPAAMTQAHPPTHIA 1805
T P TP + TTP+ T P T +P+ T T T
Sbjct: 3079 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3138
Query: 1806 PPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGS 1865
T + PT P + +V P + TG + ++ T++ +
Sbjct: 3139 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3198
Query: 1866 AEGGPTE---LTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLL 1922
T+ TP T+ P G Q T P+ T+ ++ T Q +
Sbjct: 3199 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3258
Query: 1923 PQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 1981
T+ P TT P + TTT T+TT P
Sbjct: 3259 TTT-----TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3312
Score = 122 bits (306), Expect = 5e-27
Identities = 134/599 (22%), Positives = 209/599 (34%), Gaps = 57/599 (9%)
Query: 1415 PTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNP-PVTATEEPVVSPGPTQTTLQQPL 1473
PTP+ + + T T P TP T P T T P +P TQT P+
Sbjct: 2900 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2959
Query: 1474 ELTASQLPAGP---TESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRV 1530
T + P T++P + +T + P TP P QTPT + TT
Sbjct: 2960 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPT----PTGTQTPTTTPI-----TTTT 3009
Query: 1531 TVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGS---LPVRTTP-----PQPSLTASP 1582
TV +P T + + P +T T G + P+ TT P P+ T +P
Sbjct: 3010 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3069
Query: 1583 SSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTA 1642
++ P+ + ++ +PT +G+ TP T + T P PT + + +TP+T T
Sbjct: 3070 TTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTV 3126
Query: 1643 AE-------QVPVS-PLATRSLEIVLSTEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQ 1693
Q P + P+ T + T G + + P+ + + P P P+ P
Sbjct: 3127 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3186
Query: 1694 HTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVG 1753
T + T + P TP T T TP + + P+ +G T+ P+
Sbjct: 3187 -TPITTTTTVTPTPTP------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3239
Query: 1754 TSAPVATPGPKASVITTPLQPQATTLP--------AQTLSPVLPFTPAAMTQAHPPTHIA 1805
T P TP + TTP+ T P T +P+ T T T
Sbjct: 3240 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3299
Query: 1806 PPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGS 1865
T + PT P + +V P + TG + ++ T++ +
Sbjct: 3300 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3359
Query: 1866 AEGGPTE---LTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLL 1922
T+ TP T+ P G Q T P+ T+ ++ T Q +
Sbjct: 3360 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3419
Query: 1923 PQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 1981
T+ P TT P + TTT T+TT P
Sbjct: 3420 TTT-----TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3473
Score = 122 bits (306), Expect = 5e-27
Identities = 134/599 (22%), Positives = 209/599 (34%), Gaps = 57/599 (9%)
Query: 1415 PTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNP-PVTATEEPVVSPGPTQTTLQQPL 1473
PTP+ + + T T P TP T P T T P +P TQT P+
Sbjct: 3061 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3120
Query: 1474 ELTASQLPAGP---TESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRV 1530
T + P T++P + +T + P TP P QTPT + TT
Sbjct: 3121 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPT----PTGTQTPTTTPI-----TTTT 3170
Query: 1531 TVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGS---LPVRTTP-----PQPSLTASP 1582
TV +P T + + P +T T G + P+ TT P P+ T +P
Sbjct: 3171 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3230
Query: 1583 SSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTA 1642
++ P+ + ++ +PT +G+ TP T + T P PT + + +TP+T T
Sbjct: 3231 TTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTV 3287
Query: 1643 AE-------QVPVS-PLATRSLEIVLSTEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQ 1693
Q P + P+ T + T G + + P+ + + P P P+ P
Sbjct: 3288 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3347
Query: 1694 HTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVG 1753
T + T + P TP T T TP + + P+ +G T+ P+
Sbjct: 3348 -TPITTTTTVTPTPTP------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3400
Query: 1754 TSAPVATPGPKASVITTPLQPQATTLP--------AQTLSPVLPFTPAAMTQAHPPTHIA 1805
T P TP + TTP+ T P T +P+ T T T
Sbjct: 3401 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3460
Query: 1806 PPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGS 1865
T + PT P + +V P + TG + ++ T++ +
Sbjct: 3461 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3520
Query: 1866 AEGGPTE---LTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLL 1922
T+ TP T+ P G Q T P+ T+ ++ T Q +
Sbjct: 3521 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3580
Query: 1923 PQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 1981
T+ P TT P + TTT T+TT P
Sbjct: 3581 TTT-----TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3634
Score = 122 bits (306), Expect = 5e-27
Identities = 134/599 (22%), Positives = 209/599 (34%), Gaps = 57/599 (9%)
Query: 1415 PTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNP-PVTATEEPVVSPGPTQTTLQQPL 1473
PTP+ + + T T P TP T P T T P +P TQT P+
Sbjct: 3222 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3281
Query: 1474 ELTASQLPAGP---TESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRV 1530
T + P T++P + +T + P TP P QTPT + TT
Sbjct: 3282 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPT----PTGTQTPTTTPI-----TTTT 3331
Query: 1531 TVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGS---LPVRTTP-----PQPSLTASP 1582
TV +P T + + P +T T G + P+ TT P P+ T +P
Sbjct: 3332 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3391
Query: 1583 SSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTA 1642
++ P+ + ++ +PT +G+ TP T + T P PT + + +TP+T T
Sbjct: 3392 TTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTV 3448
Query: 1643 AE-------QVPVS-PLATRSLEIVLSTEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQ 1693
Q P + P+ T + T G + + P+ + + P P P+ P
Sbjct: 3449 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3508
Query: 1694 HTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVG 1753
T + T + P TP T T TP + + P+ +G T+ P+
Sbjct: 3509 -TPITTTTTVTPTPTP------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3561
Query: 1754 TSAPVATPGPKASVITTPLQPQATTLP--------AQTLSPVLPFTPAAMTQAHPPTHIA 1805
T P TP + TTP+ T P T +P+ T T T
Sbjct: 3562 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3621
Query: 1806 PPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGS 1865
T + PT P + +V P + TG + ++ T++ +
Sbjct: 3622 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3681
Query: 1866 AEGGPTE---LTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLL 1922
T+ TP T+ P G Q T P+ T+ ++ T Q +
Sbjct: 3682 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3741
Query: 1923 PQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 1981
T+ P TT P + TTT T+TT P
Sbjct: 3742 TTT-----TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3795
Score = 122 bits (306), Expect = 5e-27
Identities = 134/599 (22%), Positives = 209/599 (34%), Gaps = 57/599 (9%)
Query: 1415 PTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNP-PVTATEEPVVSPGPTQTTLQQPL 1473
PTP+ + + T T P TP T P T T P +P TQT P+
Sbjct: 3383 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3442
Query: 1474 ELTASQLPAGP---TESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRV 1530
T + P T++P + +T + P TP P QTPT + TT
Sbjct: 3443 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPT----PTGTQTPTTTPI-----TTTT 3492
Query: 1531 TVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGS---LPVRTTP-----PQPSLTASP 1582
TV +P T + + P +T T G + P+ TT P P+ T +P
Sbjct: 3493 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3552
Query: 1583 SSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTA 1642
++ P+ + ++ +PT +G+ TP T + T P PT + + +TP+T T
Sbjct: 3553 TTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTV 3609
Query: 1643 AE-------QVPVS-PLATRSLEIVLSTEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQ 1693
Q P + P+ T + T G + + P+ + + P P P+ P
Sbjct: 3610 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3669
Query: 1694 HTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVG 1753
T + T + P TP T T TP + + P+ +G T+ P+
Sbjct: 3670 -TPITTTTTVTPTPTP------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3722
Query: 1754 TSAPVATPGPKASVITTPLQPQATTLP--------AQTLSPVLPFTPAAMTQAHPPTHIA 1805
T P TP + TTP+ T P T +P+ T T T
Sbjct: 3723 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3782
Query: 1806 PPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGS 1865
T + PT P + +V P + TG + ++ T++ +
Sbjct: 3783 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3842
Query: 1866 AEGGPTE---LTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLL 1922
T+ TP T+ P G Q T P+ T+ ++ T Q +
Sbjct: 3843 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3902
Query: 1923 PQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 1981
T+ P TT P + TTT T+TT P
Sbjct: 3903 TTT-----TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3956
Score = 122 bits (306), Expect = 5e-27
Identities = 134/599 (22%), Positives = 209/599 (34%), Gaps = 57/599 (9%)
Query: 1415 PTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNP-PVTATEEPVVSPGPTQTTLQQPL 1473
PTP+ + + T T P TP T P T T P +P TQT P+
Sbjct: 3544 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3603
Query: 1474 ELTASQLPAGP---TESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRV 1530
T + P T++P + +T + P TP P QTPT + TT
Sbjct: 3604 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPT----PTGTQTPTTTPI-----TTTT 3653
Query: 1531 TVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGS---LPVRTTP-----PQPSLTASP 1582
TV +P T + + P +T T G + P+ TT P P+ T +P
Sbjct: 3654 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3713
Query: 1583 SSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTA 1642
++ P+ + ++ +PT +G+ TP T + T P PT + + +TP+T T
Sbjct: 3714 TTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTV 3770
Query: 1643 AE-------QVPVS-PLATRSLEIVLSTEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQ 1693
Q P + P+ T + T G + + P+ + + P P P+ P
Sbjct: 3771 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3830
Query: 1694 HTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVG 1753
T + T + P TP T T TP + + P+ +G T+ P+
Sbjct: 3831 -TPITTTTTVTPTPTP------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3883
Query: 1754 TSAPVATPGPKASVITTPLQPQATTLP--------AQTLSPVLPFTPAAMTQAHPPTHIA 1805
T P TP + TTP+ T P T +P+ T T T
Sbjct: 3884 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3943
Query: 1806 PPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGS 1865
T + PT P + +V P + TG + ++ T++ +
Sbjct: 3944 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 4003
Query: 1866 AEGGPTE---LTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLL 1922
T+ TP T+ P G Q T P+ T+ ++ T Q +
Sbjct: 4004 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 4063
Query: 1923 PQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 1981
T+ P TT P + TTT T+TT P
Sbjct: 4064 TTT-----TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 4117
Score = 119 bits (297), Expect = 6e-26
Identities = 139/580 (23%), Positives = 226/580 (38%), Gaps = 108/580 (18%)
Query: 403 CEFHGTLYPPGSVVKEDCNTC---TCTSG--------------KWECSTAVCPAECSVTG 445
C+++ T+ +VK +C TC++G WEC C+ G
Sbjct: 4435 CKYNNTV----EIVKVECEPPPMPTCSNGLQPVRVEDPDGCCWHWECD-----CYCTGWG 4485
Query: 446 DIHFTTFDGRRYTFPATCQYILAK--SRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQ 503
D H+ TFDG Y++ C Y+L + S S F V + N C N +C +++ ++ H+
Sbjct: 4486 DPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSCPRTL-IVRHE 4544
Query: 504 DPR---RQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREG 560
+ V + + ++ + PY E+ + ++ +GV V Y+ G
Sbjct: 4545 TQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVLVSYN--G 4602
Query: 561 LRLYLQVD-QRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLV- 618
L +++ R+ +T G CGT T DD + P G S + + W P
Sbjct: 4603 LSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCP 4662
Query: 619 -SGSPLDPCDVHLQAASYSV--------QACSVLTGEMFAPCSAFLSPVPYFEQCRRDAC 669
S S V + + C ++ +FA C A + P Y++ C D+C
Sbjct: 4663 HSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSC 4722
Query: 670 -RCGQPCLCATLAHYAHLCRRHGLPVDFRARL-PACALSCEASKEYSPCVAPCGRTCQDL 727
G CA+L YA LC + + +D+R AC + C + +EY C TC+
Sbjct: 4723 FMPGSSLECASLQAYAALCAQQNICLDWRNHTHGACLVECPSHREYQACGPAEEPTCKSS 4782
Query: 728 ASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQA-DLCVPRNQCSCHFQGVDYPP---G 783
+S + + VEGC CP T D+CV C C G D P G
Sbjct: 4783 SSQQ----------NNTVLVEGCFCPEGTMNYAPGFDVCV--KTCGC--VGPDNVPREFG 4828
Query: 784 DSDIPSLGHCHCKDG--VMSCD----SRAPAAACPAGQVF----VNCSDLHTDLELSRER 833
+ +C C +G + C S+ P C + VN +D ++ + +
Sbjct: 4829 EHFEFDCKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTCCNITVCKCN 4888
Query: 834 T--CEQQ--LLNLSVSARGPCLSGCACP------QGLLRHGDACFLPEECPCTWKGKEYF 883
T C+++ + L + + G CP +G+ HG+A EY
Sbjct: 4889 TSLCKEKPSVCPLGFEVKSKMVPGRCCPFYWCESKGVCVHGNA--------------EYQ 4934
Query: 884 PGDQV-MSPCHTCVCQ--------RGSFQCTLHPCASTCT 914
PG V S C CVC CT PC ++C+
Sbjct: 4935 PGSPVYSSKCQDCVCTDKVDNNTLLNVIACTHVPCNTSCS 4974
Score = 115 bits (289), Expect = 5e-25
Identities = 109/399 (27%), Positives = 155/399 (38%), Gaps = 49/399 (12%)
Query: 74 ERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTC 133
E D C WG H TFDGLYY G +Y LV P +F + + N + +C
Sbjct: 4476 ECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSC 4535
Query: 134 SRAVSLFFVGEQEIHLAKEVTHGGMRVQ---------LPH-VMGSARLQQLAGYVIVRHQ 183
R +L E + L K V M+VQ LP+ G Q YV+ +
Sbjct: 4536 PR--TLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPE 4593
Query: 184 SAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQE 243
++++G S T G CG DD + SG++ + W
Sbjct: 4594 LGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLV 4653
Query: 244 QAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQ------CEALLRPPFDACHAYVSPLPF 297
P++P P +SS + P + G ++ C+ + F CHA V P +
Sbjct: 4654 NDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHY 4713
Query: 298 TASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLR-QCTVHCKEKAFTYNE 356
+C D C G + C +L YA CAQ L WR C V C ++ E
Sbjct: 4714 YDACVFDSCFMPGS-SLECASLQAYAALCAQQNICLD-WRNHTHGACLVECP----SHRE 4767
Query: 357 CIACCPA---SCHPRASCVDSEIACVDGCYCPNG---------LIFEDGGCVAPAECPCE 404
AC PA +C +S ++ + V+GC+CP G + + GCV P P E
Sbjct: 4768 YQACGPAEEPTCKSSSSQQNNTV-LVEGCFCPEGTMNYAPGFDVCVKTCGCVGPDNVPRE 4826
Query: 405 FHGTLYPPGSVVKEDCNTCTCTSGKWECSTAVC-PAECS 442
F G + DC C C G S +C P CS
Sbjct: 4827 F-------GEHFEFDCKNCVCLEGG---SGIICQPKRCS 4855
Score = 113 bits (282), Expect = 3e-24
Identities = 147/644 (22%), Positives = 226/644 (35%), Gaps = 78/644 (12%)
Query: 1385 CVYLEDCV---EPAVWVPTEALGNETLPPSQGLPTP----SDEEPQLSQESP---RTPTH 1434
C ++ C+ P P+ + T P P+P + P + SP T T
Sbjct: 1389 CWPMDKCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTP 1448
Query: 1435 RPALTPAAPLTTALNPPVTATEEP-VVSPGPTQTTLQQPLELTASQLPAGPTESPASKGV 1493
P TP+ P++T PP T T P +P P TT P T + P P + +
Sbjct: 1449 PPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPI 1508
Query: 1494 T--ASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPR 1551
T AS +P T S TP P TT +T + + ++ SPP
Sbjct: 1509 TPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPP--- 1565
Query: 1552 FPLMTKAVTVRGHGSLPVRTTPPQPSLTAS--PSSRPVASPGAISRSPTSSGSHKAVLTP 1609
P T S P TTP P++T + P + + P + +P + + T
Sbjct: 1566 -PTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTT 1624
Query: 1610 AVTKVISRTGVPQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGH 1669
+T S T +P T +PS P T T SP T +
Sbjct: 1625 PITPPTSTTTLPPTT------TPSPPPTTTTTPPPTTTPSPPTTTT-------------P 1665
Query: 1670 SQPMGSPASPQPHPLPSAP----PRPAQHTTMATRSPALPPETPAAASLSTATDGLAATP 1725
S P+ + +P P PS+P P P TTM T SP P +P + + ++ + P
Sbjct: 1666 SPPITTTTTPPPTTTPSSPITTTPSPPT-TTMTTPSPTTTPSSPITTTTTPSSTTTPSPP 1724
Query: 1726 FMSLESTRPSQLLSGLPPDTSL-PLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTL 1784
++ T PS + PP T++ L TS+P+ T S+ P +TT P
Sbjct: 1725 PTTM--TTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPC 1782
Query: 1785 SPVLPFT---PAAMTQAHPP---THIAPPAAGT--APGLLLGATLPTS------GVLPVA 1830
P+ +T + H P T + G A + AT+ G V
Sbjct: 1783 VPLCNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANISCRATMYPDVPIGQLGQTVVC 1842
Query: 1831 EGTASMVSVVPRKSTTGKVAI-----------LSKQVSLPTSMYGSAEGGPT--ELTPAT 1877
+ + ++ + G + + + V+ PT+M + PT TP T
Sbjct: 1843 DVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPIT 1902
Query: 1878 SHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLAEAHGTSAGPHL 1937
+ P G Q T P+ T+ ++ T Q + T+ P
Sbjct: 1903 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT-----TTVTPTP 1957
Query: 1938 AAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 1981
TT P + TTT T+TT P
Sbjct: 1958 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2001
Score = 112 bits (281), Expect = 4e-24
Identities = 182/770 (23%), Positives = 255/770 (33%), Gaps = 128/770 (16%)
Query: 1336 CEWRYDACASPCFQTCRDPRAASCR-DVPRVEGCVPVCPTPQ-VLDEVTQRCVYLEDC-- 1391
CEW Y+ C + F+TCR V +EGC P CP + + +E ++CV + C
Sbjct: 1130 CEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGC 1189
Query: 1392 ------VEPAVWVPTEALGNETLPPSQGLPTPSDEEPQ-LSQESPRTPTHRPALTPAAPL 1444
P VPTE + + EE + L+Q + P +
Sbjct: 1190 YVEDTHYPPGASVPTEETCKSCVCTNSSQVVCRPEEGKILNQTQDGAFCYWEICGPNGTV 1249
Query: 1445 TTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTP 1504
N T ++ T T P T + PT S + TP
Sbjct: 1250 EKHFNICSITTRPSTLTTFTTITLPTTPTTFTTTTTTTTPTSSTV----------LSTTP 1299
Query: 1505 ESSSLP---VALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTV 1561
+ L + P+ G G ET G+P + RS P L V
Sbjct: 1300 KLCCLWSDWINEDHPSSGSDDGDRETFDGV---CGAPE-DIECRSVKDPHLSLEQLGQKV 1355
Query: 1562 R---------------GHG--------SLPVRTTPPQPSLTASPSSRPVASPGAISRSPT 1598
+ G+G + V P +PS P +P S PT
Sbjct: 1356 QCDVSVGFICKNEDQFGNGPFGLCYDYKIRVNCCWPMDKCITTPSP-PTTTP---SPPPT 1411
Query: 1599 SSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEI 1658
S+ + TP+ + T P PT ++PS P+T T SP
Sbjct: 1412 STTTLPPTTTPSPPTTTTTT--PPPT-----TTPSPPITTTTTPPPTTTPSP-------- 1456
Query: 1659 VLSTEKGEAGHSQPMGSPASPQPHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTAT 1718
+ST + P +P P +PP T T +P+ P TP ST T
Sbjct: 1457 PISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTT 1516
Query: 1719 DGLAATPF-MSLESTRPSQLLSGLPPDTS--LPLAKVGTSAPVATPGPKASVITTPLQPQ 1775
TP + +T P + PP T+ P T P TP P + TTP P
Sbjct: 1517 LPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTP-PPT 1575
Query: 1776 ATTLPAQTLSPVLP----FTPAAMTQAHPPTHIA---PPAAGTAPGLLLGATLPTSGVLP 1828
T P T +P P TP T PPT PP +P T PTS
Sbjct: 1576 TTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTL 1635
Query: 1829 VAEGTAS---MVSVVPRKSTTGKVAILSKQVSLPTSMYGSAEGGPTELTPATSHPLTPLV 1885
T S + P +TT S PT+ S T P T+ P +P+
Sbjct: 1636 PPTTTPSPPPTTTTTPPPTTT---------PSPPTTTTPSPPITTTTTPPPTTTPSSPIT 1686
Query: 1886 AEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLAEAHGTSAGPHLAAEP--VD 1943
P P PT+ S ++ T P + P T+ P P
Sbjct: 1687 TTPSPPTTTMTTPSPTTTPSSPITTTTTPSST---TTPSPPPTTMTTPSPTTTPSPPTTT 1743
Query: 1944 EATTEPSGRSAPAL------SIVEGLAEALATTTEANTSTTCVPIAEQDCVRHICLEGQL 1997
T P+ S+P SI +TTT +T CVP+ G L
Sbjct: 1744 MTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTT---PTTPCVPLCN--------WTGWL 1792
Query: 1998 IRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLW--ECACRCSIFPDL 2045
+ H P G + GD C P W +CR +++PD+
Sbjct: 1793 DSGKPNFHKPGG-----------DTELIGDVCGPGWAANISCRATMYPDV 1831
Score = 96.3 bits (238), Expect = 4e-19
Identities = 118/550 (21%), Positives = 187/550 (34%), Gaps = 76/550 (13%)
Query: 1443 PLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPH 1502
P+ LN + V+ T TT T ++ P PT +P + T
Sbjct: 1862 PMAFCLNYEINVQCCECVTQPTTMTT-------TTTENPTPPTTTPITTTTTV------- 1907
Query: 1503 TPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVR 1562
TP + P QTPT + TT TV +P T + + P +T TV
Sbjct: 1908 TPTPT--PTGTQTPTTTPI-----TTTTTVTPTPTPTGTQTPTTTP------ITTTTTV- 1953
Query: 1563 GHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQ 1622
T P P+ T +P++ P+ + ++ +PT +G+ TP T + T P
Sbjct: 1954 --------TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPT 2002
Query: 1623 PTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPH 1682
PT + + +TP+T T V +P T + + + P+ + + P
Sbjct: 2003 PTPTGTQTPTTTPITTTTT----VTPTPTPTGT----------QTPTTTPITTTTTVTPT 2048
Query: 1683 PLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLP 1742
P P+ P T + T + P TP T T TP + + P+ +G
Sbjct: 2049 PTPTGTQTPTT-TPITTTTTVTPTPTP------TGTQTPTTTPITTTTTVTPTPTPTGTQ 2101
Query: 1743 PDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLP--------AQTLSPVLPFTPAA 1794
T+ P+ T P TP + TTP+ T P T +P+ T
Sbjct: 2102 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2161
Query: 1795 MTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSK 1854
T T T + PT P + +V P + TG +
Sbjct: 2162 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2221
Query: 1855 QVSLPTSMYGSAEGGPTE---LTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSAR 1911
++ T++ + T+ TP T+ P G Q T P+ T+ ++
Sbjct: 2222 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2281
Query: 1912 TAPQDSMLVLLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTT 1971
T Q + T+ P TT P + TTT
Sbjct: 2282 TGTQTPTTTPITTT-----TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2336
Query: 1972 EANTSTTCVP 1981
T+TT P
Sbjct: 2337 PITTTTTVTP 2346
Score = 75.5 bits (184), Expect = 7e-13
Identities = 70/313 (22%), Positives = 118/313 (37%), Gaps = 46/313 (14%)
Query: 904 CTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVK--STSDVSFSVIVENVNCYSSG 961
C C CT +GD HY TFDGL + + G C LV+ S S +F V ++N +C +
Sbjct: 4472 CWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPND 4531
Query: 962 MI-CRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEV---------HTWRVGFFTLVHF 1011
+ C + + + ++ P ++Q V ++ G +V
Sbjct: 4532 KVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDI 4591
Query: 1012 PQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSW 1071
P+ + + ++ + ++ G CG T ++ P ++N + W
Sbjct: 4592 PELGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQW 4651
Query: 1072 AAVE-----CPDTLD----------------PRDMCVLNPLREPFAKKECSILLSEVFEI 1110
+ CP + P C +PL C ++ +F
Sbjct: 4652 LVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPL--------CQLIKDSLFAQ 4703
Query: 1111 CHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWR--TPRLCPY 1168
CH +V +Y C+ D+C G EC AS+ AYA C Q + +DWR T C
Sbjct: 4704 CHALVPPQHYYDACVFDSC-FMPGSSLEC--ASLQAYAALCAQQNICLDWRNHTHGACLV 4760
Query: 1169 DCDFFNKVLGKGP 1181
+C + GP
Sbjct: 4761 ECPSHREYQACGP 4773
Score = 67.4 bits (163), Expect = 2e-10
Identities = 89/398 (22%), Positives = 145/398 (36%), Gaps = 67/398 (16%)
Query: 2030 CPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDC-KSANLGHL 2088
C C CSI+ ++TFDG + Y+ Q C ++++LG
Sbjct: 851 CTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDY----------CGQNSSLGS- 899
Query: 2089 NWPPFCLVMLNM----THLAHQVTIDRFNRKVTVDLQPVWPPVSR------YGFRIEDTG 2138
F ++ N+ T + I F + + L+ V + + + G
Sbjct: 900 ----FSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYTTREVG 955
Query: 2139 HMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGA 2198
++ + + I + W + ++ + + K GLCG D + ND T +D VV
Sbjct: 956 QYLVVESSTGIIVIW-DKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSE 1014
Query: 2199 EDPAPFLDSWQVPSSLTSVGQTRFRPDSC---------ATTDCSPCLRMVSNRTFSACHR 2249
D F +SW+ + V P+ C A CS ++ + FS CH
Sbjct: 1015 LD---FGNSWKEAPTCPDVSTN---PEPCSLNPHRRSWAEKQCS----ILKSSVFSICHS 1064
Query: 2250 FVPPESFCELWIRDTKYVQQP------CVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSD 2303
V P+ F E + D+ C A+ Y C K C+ WR D CP C
Sbjct: 1065 KVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACVFWRTPDLCPIFCDYY 1124
Query: 2304 STYQACVTACEPP-----KTCQ--DGILGPLDPEHCQVLGEGCV--CSEGTILHRRHSAL 2354
+ C EP +TC+ +GI + + EGC C + ++
Sbjct: 1125 NPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYL----EGCYPRCPKDRPIYEEDLKK 1180
Query: 2355 CIPEAKCAC--TDSMGVPRALGETWNSSLSGCCQHQCQ 2390
C+ KC C D+ P A T + S C + Q
Sbjct: 1181 CVTADKCGCYVEDTHYPPGASVPTEETCKSCVCTNSSQ 1218
Score = 55.8 bits (133), Expect = 6e-07
Identities = 92/411 (22%), Positives = 146/411 (35%), Gaps = 61/411 (14%)
Query: 1979 CVPIAEQDCVRH--ICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECA 2036
CVP+++ C H + GQ I N + C A G C C
Sbjct: 345 CVPVSQCHCRLHGHLYTPGQEI-TNDCEQCVCNA---------------GRWVCKDLPCP 388
Query: 2037 CRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLV 2096
C++ TFDG + Y+L++ + L + A G +
Sbjct: 389 GTCALEGGSHITTFDGKTYTFHGDCYYVLAKGDHN--DSYALLGELAPCGSTDKQTCLKT 446
Query: 2097 MLNMTHLAHQVTIDRFNRKVTV-DLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQ-WL 2154
++ + V + + + V + +LQ P V+ + + M+ +++Q L
Sbjct: 447 VVLLADKKKNVVVFKSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQL 506
Query: 2155 HSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSL 2214
+ V + S+ Q GLCG +G +D G V A F ++W+ SS
Sbjct: 507 APVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATG---AGFANTWKAQSSC 563
Query: 2215 TSVGQTRFRPDSCATTDCSP------CLRMVSNRT-FSACHRFVPPESFCELWIRDTKYV 2267
+ + D C+ S C + T F CH V P + + DT
Sbjct: 564 HD--KLDWLDDPCSLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNC 621
Query: 2268 QQP----CVALTVYVAMCHKFHVCI-EWRRS------DYCP----FLCSSDSTYQACVTA 2312
Q C AL+ Y C V + WR CP FL + + Q C +
Sbjct: 622 QNNEDCLCAALSSYARACTAKGVMLWGWREHVCNKDVGSCPNSQVFLYNLTTCQQTCRSL 681
Query: 2313 CEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCAC 2363
E C +G P+D GC C + T L + C+P AKC+C
Sbjct: 682 SEADSHCLEG-FAPVD---------GCGCPDHTFLDEK--GRCVPLAKCSC 720
Score = 55.5 bits (132), Expect = 8e-07
Identities = 58/242 (23%), Positives = 93/242 (38%), Gaps = 22/242 (9%)
Query: 2131 GFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLT 2188
G IE + + + + + + W LM+ +K + H GLCG +G +
Sbjct: 125 GLLIEKSDAYTKVYSRAGLTLMWNREDALML---ELDTKFRNHTCGLCGDYNGLQSYSEF 181
Query: 2189 LKDGSVVGGAEDPAPFLDSWQV--PSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRTFSA 2246
L DG + P F + ++ P + + P SC+ C R+++ F+
Sbjct: 182 LSDGVLFS----PLEFGNMQKINQPDVVCEDPEEEVAPASCSEHRAE-CERLLTAEAFAD 236
Query: 2247 CHRFVPPESFCELWIRDTKYVQ--QPCVALTV--YVAMC-HKFHVCIEWRRSDYCPFLCS 2301
C VP E + +D CV TV + C H WR + CP C
Sbjct: 237 CQDLVPLEPYLRACQQDRCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATLCPKTCP 296
Query: 2302 SDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKC 2361
+ Y + C TC + L EH +GC C EGT+ + C+P ++C
Sbjct: 297 GNLVYLESGSPCMD--TCSHLEVSSLCEEHRM---DGCFCPEGTVYDDIGDSGCVPVSQC 351
Query: 2362 AC 2363
C
Sbjct: 352 HC 353
Score = 52.8 bits (125), Expect = 5e-06
Identities = 78/325 (24%), Positives = 111/325 (34%), Gaps = 77/325 (23%)
Query: 1409 PPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTT 1468
P G TP+ + TPT TP P+T T +P PT T
Sbjct: 4142 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-------TTPITTTTTVTPTPTPTGTQ 4194
Query: 1469 LQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETT 1528
P + + + T +P + T P T S+S P+ T
Sbjct: 4195 TGPPTHTSTAPIAELTTSNPPPESST------PQTSRSTSSPL---------------TE 4233
Query: 1529 RVTVIFAGSPNITVSSRSPPA-PRFPLMTKAVTVRGHGSLPVRTTPPQPSLTASPSSRPV 1587
T++ P I ++S +PP+ P P T GH T P PS T SP
Sbjct: 4234 STTLLSTLPPAIEMTSTAPPSTPTAPTTTSG----GH------TLSPPPSTTTSP----- 4278
Query: 1588 ASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTAAEQVP 1647
PG +R T++GS A V + P PT STP + T P
Sbjct: 4279 --PGTPTRG-TTTGSSSAPTPSTVQTTTTSAWTPTPTPL------STPSIIRTTGLRPYP 4329
Query: 1648 VSPLATRSLEIVLSTEKGEAGHSQPMGS--------------------PASPQPHPLPS- 1686
S L L GE ++ G P++P P P PS
Sbjct: 4330 SSVLICCVLNDTYYA-PGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSK 4388
Query: 1687 APPRPAQHTTMATRSP--ALPPETP 1709
+ P P++ ++ ++ PPE P
Sbjct: 4389 STPTPSKPSSTPSKPTPGTKPPECP 4413
>gi|169202626 PREDICTED: similar to mucin 5, partial [Homo sapiens]
Length = 2013
Score = 612 bits (1577), Expect = e-174
Identities = 381/1126 (33%), Positives = 548/1126 (48%), Gaps = 65/1126 (5%)
Query: 78 ICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAV 137
+C WG H +TFDG + G +Y + F+IQ+ + S+ T SR
Sbjct: 80 VCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQE--SAAPTLSRV- 136
Query: 138 SLFFVGEQEIHLAK-EVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAV 196
L V I L K V G V LP +QQ + Y V + L W+ ++
Sbjct: 137 -LMKVDGVVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKVEARLGLVLMWNHDDSL 195
Query: 197 YIKMSPELLGWTHGLCGNNNADPK-DDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTS 255
+++ + T GLCG+ N P +L++ + KLT +EF + Q + P
Sbjct: 196 LLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTP--MEFGNL---QKMDDPTEQCQD 250
Query: 256 SLPRPPCLQQNPGTMQGVYEQCEALLRPP-FDACHAYVSPLPFTASCTSDLC--QSMGDV 312
+P PP +N T G+ CE LL F C A V + +C DLC + +
Sbjct: 251 PVPEPP---RNCSTGFGI---CEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLL 304
Query: 313 ATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCV 372
+ C LAEY+R C AG Q WR C C Y+EC + C +C +
Sbjct: 305 SCVCHTLAEYSRQCTHAGGLPQDWRGP-DFCPQKCPNN-MQYHECRSPCADTCSNQEHSR 362
Query: 373 DSEIACVDGCYCPNGLIFED---GGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGK 429
E CV GC+CP G + +D GCV ++C C ++G Y PG+ DC CTC+ G+
Sbjct: 363 ACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYSTDCTNCTCSGGR 422
Query: 430 WECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQ 489
W C CP CSV G HF+TFDG++YT C Y+L K S FTV + CGL
Sbjct: 423 WSCQEVPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCGLTD 482
Query: 490 DGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTN 549
C++SV++ L + V + +G+V L Y +P + I R S+ F+ +T+
Sbjct: 483 SETCLKSVTLSL-DGVQTVVVIKASGEVFLNQIYTQLPISAANV-TIFRPSTFFIIAQTS 540
Query: 550 VGVRV-LYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSW 608
+G+++ L ++L++Q+ + T GLCG FN DDF + GV E+T F N++
Sbjct: 541 LGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTF 600
Query: 609 KTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGE--MFAPCSAFLSPVPYFEQCRR 666
KT +AC P + S DPC + ++ Y+ CS LT F C A + P Y+ C
Sbjct: 601 KTQAAC-PNIRNSFEDPCSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMF 659
Query: 667 DACRC--GQPCLCATLAHYAHLCRRHGLPVDFRARLPACA---LSCEASKEYSPCVAPCG 721
D C C + CLCA L+ Y H C G+ + R C +C S Y V+ C
Sbjct: 660 DTCNCERSEDCLCAALSSYVHACAAKGVQLG-GWRDGVCTKPMTTCPKSMTYHYHVSTCQ 718
Query: 722 RTCQDLASPE-ACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDY 780
TC+ L+ + C V V+GC CP T+LD CV + C C+ +G
Sbjct: 719 PTCRSLSEGDITCSVGFIP-------VDGCICPKGTFLDDTGK-CVQASNCPCYHRGSMI 770
Query: 781 PPGDSDIPSLGHCHCKDGVMSC-DSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQL 839
P G+S S C C G +SC +APA C A VF +C + C++
Sbjct: 771 PNGESVHDSGAICTCTHGKLSCIGGQAPAPVCAAPMVFFDCRNATPG---DTGAGCQKSC 827
Query: 840 LNLSVSARGP-CLSGCACPQGLLRHGDA-CFLPEECPCTWKGKEYFPGDQVMSPCHTCVC 897
L ++ P C+ GC CP GL+ G+ C E+CPC Y G + C+TC C
Sbjct: 828 HTLDMTCYSPQCVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRVGCNTCTC 887
Query: 898 QRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLV------KSTSDVSFSVI 951
++CT PC +TC YGD HY TFDG + F G C+ LV K ++ SF V+
Sbjct: 888 DSRMWRCTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVV 947
Query: 952 VENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESF-LDDKQEV-HTWRVGFFTLV 1009
ENV C ++G C K I I +G F+ + E D+ QEV +T R LV
Sbjct: 948 TENVPCGTTGTTCSKAIKIFLGG----FELKLSHGKVEVIGTDESQEVPYTIRQMGIYLV 1003
Query: 1010 HFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGS 1069
+ LLWD++T++ + P+++G++ GLCGNFD +N+ T + + EFG+
Sbjct: 1004 VDTDIGLVLLWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGN 1063
Query: 1070 SWA-AVECPDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDT 1128
SW + CPD L P+D C NP R+ +A+K+CSIL F CH V+ +Y C+ D
Sbjct: 1064 SWKLSPSCPDALAPKDPCTANPFRKSWAQKQCSILHGPTFAACHAHVEPARYYEACVNDA 1123
Query: 1129 CGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFN 1174
C C GGDCECFC +V+AYA C + G+ V WRTP +CP CD++N
Sbjct: 1124 CACDSGGDCECFCTAVAAYAQACHEVGLCVSWRTPSICPLFCDYYN 1169
Score = 231 bits (590), Expect = 6e-60
Identities = 152/486 (31%), Positives = 221/486 (45%), Gaps = 62/486 (12%)
Query: 359 ACCPASCHPR-ASCVDSEIACVDGCYCPNGLIFE-DGGCVAPAECPCEFHGTLYPPGSVV 416
A C SCH +C + CV GC CP+GL+ + +GGC+ +CPC + Y G +
Sbjct: 821 AGCQKSCHTLDMTCYSPQ--CVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTI 878
Query: 417 KEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSG-- 474
+ CNTCTC S W C+ C A C+V GD H+ TFDG+ Y+F C+Y L ++ G
Sbjct: 879 RVGCNTCTCDSRMWRCTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKD 938
Query: 475 ----TFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYT 530
+F V +N PCG C +++ + L G L K+ T
Sbjct: 939 STQDSFRVVTENVPCGTTGT-TCSKAIKIFL------------GGFELKLSHGKVEVIGT 985
Query: 531 DDAFEIR---RLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQ 587
D++ E+ R ++L V T++G+ +L+D++ +++ + + GLCG F+
Sbjct: 986 DESQEVPYTIRQMGIYLVVDTDIGLVLLWDKK-TSIFINLSPEFKGRVCGLCGNFDDIAV 1044
Query: 588 DDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEM 647
+DF + FGNSWK +C ++ P DPC + S++ + CS+L G
Sbjct: 1045 NDFATRSRSVVGDVLEFGNSWKLSPSCPDALA--PKDPCTANPFRKSWAQKQCSILHGPT 1102
Query: 648 FAPCSAFLSPVPYFEQCRRDACRCGQ----PCLCATLAHYAHLCRRHGLPVDFRARLPAC 703
FA C A + P Y+E C DAC C C C +A YA C GL V +R C
Sbjct: 1103 FAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCVSWRTP-SIC 1161
Query: 704 ALSCE-------ASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGC--ACPP 754
L C+ Y PC PC RTC++ GD L +EGC CPP
Sbjct: 1162 PLFCDYYNPEGQCEWHYQPCGVPCLRTCRN---------PRGDCLRDVWGLEGCYPKCPP 1212
Query: 755 DT-YLDTQADLCV-----PRNQCSCHFQGVDYPPGDSDIPSLGHCH---CKDGVMSCDSR 805
+ D CV P CH G Y PG + +PS +C C + + C +
Sbjct: 1213 EAPIFDEDKMQCVATCPTPPLPPRCHVHGKSYRPG-AVVPSDKNCQSCLCTERGVECTYK 1271
Query: 806 APAAAC 811
A A C
Sbjct: 1272 AEACVC 1277
Score = 184 bits (468), Expect = 8e-46
Identities = 136/449 (30%), Positives = 201/449 (44%), Gaps = 68/449 (15%)
Query: 53 CDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRH--- 109
CD R + T C + C +G H TFDG Y +G YTLV H
Sbjct: 887 CDSRMWRCTDDPCL----------ATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGG 936
Query: 110 -EPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRV-------Q 161
+ SF + N P CG++ TCS+A+ +F G + +++HG + V +
Sbjct: 937 KDSTQDSFRVVTENVP-CGTTGTTCSKAIKIFLGGFE-----LKLSHGKVEVIGTDESQE 990
Query: 162 LPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKD 221
+P+ ++Q+ Y++V L WD ++++I +SPE G GLCGN + +
Sbjct: 991 VPYT-----IRQMGIYLVVDTDIGLVLLWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVN 1045
Query: 222 DLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALL 281
D T S + DV+EF +SW+ P + P+ PC NP +QC L
Sbjct: 1046 DFATRSRSVVGDVLEFGNSWKLS-----PSCPDALAPKDPCTA-NPFRKSWAQKQCSILH 1099
Query: 282 RPPFDACHAYVSPLPFTASCTSDLC--QSMGDVATWCRALAEYARACAQAGRPLQGWRTQ 339
P F ACHA+V P + +C +D C S GD +C A+A YA+AC + G + WRT
Sbjct: 1100 GPTFAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCVS-WRTP 1158
Query: 340 LRQCTVHCK------EKAFTYNECIACCPASC-HPRASCVDSEIACVDGCY--CP-NGLI 389
C + C + + Y C C +C +PR C+ ++ ++GCY CP I
Sbjct: 1159 -SICPLFCDYYNPEGQCEWHYQPCGVPCLRTCRNPRGDCL-RDVWGLEGCYPKCPPEAPI 1216
Query: 390 FEDGGCVAPAECP-------CEFHGTLYPPGSVVKED--CNTCTCTSGKWECSTAVCPAE 440
F++ A CP C HG Y PG+VV D C +C CT EC+
Sbjct: 1217 FDEDKMQCVATCPTPPLPPRCHVHGKSYRPGAVVPSDKNCQSCLCTERGVECTYKAEACV 1276
Query: 441 CSVT------GDIHFTTFDGRRYTFPATC 463
C+ GD+ + T DG A C
Sbjct: 1277 CTYNGQRFHPGDVIYHTTDGTGGCISARC 1305
Score = 79.3 bits (194), Expect = 5e-14
Identities = 69/285 (24%), Positives = 110/285 (38%), Gaps = 18/285 (6%)
Query: 2107 VTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASK 2166
V I V V+ PV P S+ G I+ + + + + W H L++ +K
Sbjct: 143 VVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKVEARLGLVLMWNHDDSLLLELDTK 202
Query: 2167 TSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDS 2226
+ + GLCG +G L + + P F + ++ P
Sbjct: 203 YAN-KTCGLCGDFNGMPVVSELLSHNTKL----TPMEFGNLQKMDDPTEQCQDPVPEPPR 257
Query: 2227 CATTDCSPCLRMVSNRTFSACHRFVPPESFCEL------WIRDTKYVQQPCVALTVYVAM 2280
+T C ++ + FS C V S+ E + DT + C L Y
Sbjct: 258 NCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLLSCVCHTLAEYSRQ 317
Query: 2281 C-HKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGC 2339
C H + +WR D+CP C ++ Y C + C TC + +HC GC
Sbjct: 318 CTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCAD--TCSNQEHSRACEDHCVA---GC 372
Query: 2340 VCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGC 2384
C EGT+L C+P +KCAC + G A G T+++ + C
Sbjct: 373 FCPEGTVLDDIGQTGCVPVSKCACVYN-GAAYAPGATYSTDCTNC 416
Score = 72.4 bits (176), Expect = 6e-12
Identities = 78/332 (23%), Positives = 122/332 (36%), Gaps = 44/332 (13%)
Query: 2019 GLAVRVGGDRCC---PLWECA-----CRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPD 2070
G +RVG + C +W C C+++ D ++TFDG + + Y L Q+
Sbjct: 875 GQTIRVGCNTCTCDSRMWRCTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNH- 933
Query: 2071 EMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPV--WPPVS 2128
D + + C A ++ + F K++ V
Sbjct: 934 ----CGGKDSTQDSFRVVTENVPCGTTGTTCSKAIKIFLGGFELKLSHGKVEVIGTDESQ 989
Query: 2129 RYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLT 2188
+ I G ++ T + + W + + I S K + GLCG D A ND
Sbjct: 990 EVPYTIRQMGIYLVVDTDIGLVLLWDKKTSIFI-NLSPEFKGRVCGLCGNFDDIAVNDFA 1048
Query: 2189 LKDGSVVGGAEDPAPFLDSWQV----PSSLTSVGQTRFRP--DSCATTDCSPCLRMVSNR 2242
+ SVVG D F +SW++ P +L P S A CS ++
Sbjct: 1049 TRSRSVVG---DVLEFGNSWKLSPSCPDALAPKDPCTANPFRKSWAQKQCS----ILHGP 1101
Query: 2243 TFSACHRFVPPESFCELWIRDTKYVQQP------CVALTVYVAMCHKFHVCIEWRRSDYC 2296
TF+ACH V P + E + D C A+ Y CH+ +C+ WR C
Sbjct: 1102 TFAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCVSWRTPSIC 1161
Query: 2297 PFLC-------SSDSTYQACVTACEPPKTCQD 2321
P C + YQ C C +TC++
Sbjct: 1162 PLFCDYYNPEGQCEWHYQPCGVPC--LRTCRN 1191
Score = 70.1 bits (170), Expect = 3e-11
Identities = 148/661 (22%), Positives = 225/661 (34%), Gaps = 108/661 (16%)
Query: 1977 TTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECA 2036
T CVP+++ CV N + + P C + GG C C
Sbjct: 386 TGCVPVSKCACV-----------YNGAAYAPGATYSTDCTNCTCS---GGRWSCQEVPCP 431
Query: 2037 CRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLV 2096
CS+ F TFDG + + Y+L++ D + + + L CL
Sbjct: 432 GTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCGLTD---SETCLK 488
Query: 2097 MLNMTHLAHQ-VTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPS---DIQIQ 2152
+ ++ Q V + + + +V ++ P+S I ++I S + +Q
Sbjct: 489 SVTLSLDGVQTVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQ 548
Query: 2153 WLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPS 2212
+ + L + A K + Q GLCG + A+D G V A A F ++++ +
Sbjct: 549 LVPTMQLFMQLAPKL-RGQTCGLCGNFNSIQADDFRTLSGVVEATA---AAFFNTFKTQA 604
Query: 2213 SLTSVGQTRFRPDSCATTDCSPCLRMVSNRT-----FSACHRFVPPESFCELWIRDTKYV 2267
+ ++ + P S + + S T F CH V P ++ + DT
Sbjct: 605 ACPNIRNSFEDPCSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNC 664
Query: 2268 QQP----CVALTVYVAMCHKFHVCIEWRRSDYCP---FLCSSDSTYQACVTACEPPKTCQ 2320
++ C AL+ YV C V + R C C TY V+ C+P TC+
Sbjct: 665 ERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVSTCQP--TCR 722
Query: 2321 DGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSS 2380
G + + +GC+C +GT L + C+ + C C G GE+ + S
Sbjct: 723 SLSEGDITCSVGFIPVDGCICPKGTFLD--DTGKCVQASNCPCY-HRGSMIPNGESVHDS 779
Query: 2381 LSGC-CQH---QCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQ 2436
+ C C H C PV C +P V P G C Q
Sbjct: 780 GAICTCTHGKLSCIGGQAPAPV---CAAPM---------VFFDCRNATPGDTGAGC---Q 824
Query: 2437 TLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDS 2496
C L TC YS +C VP C L+ G
Sbjct: 825 KSCHTLDMTC------------------YSPQC---------VPGCVCPDGLVADGEG-G 856
Query: 2497 CCTSYFCACGDCPDSIPECQEGEALTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALV 2556
C T+ DCP C EA T + C C +RC C A
Sbjct: 857 CITA-----EDCP-----CVHNEASYRAGQTIRVGCNTCTCDSRMWRCTDDPC---LATC 903
Query: 2557 EVWSPDRCCPYK----SCECDCDTIPVPRCHLWEKSQLDEEFMHSVENV-CGCAKYECVK 2611
V+ + S DC+ V H K + F ENV CG C K
Sbjct: 904 AVYGDGHYLTFDGQSYSFNGDCEYTLVQN-HCGGKDSTQDSFRVVTENVPCGTTGTTCSK 962
Query: 2612 A 2612
A
Sbjct: 963 A 963
Score = 65.9 bits (159), Expect = 6e-10
Identities = 106/450 (23%), Positives = 150/450 (33%), Gaps = 73/450 (16%)
Query: 1336 CEWRYDACASPCFQTCRDPRAASCRDVPRVEGCVPVC-PTPQVLDEVTQRCVYLEDCVEP 1394
CEW Y C PC +TCR+PR RDV +EGC P C P + DE +CV C P
Sbjct: 1174 CEWHYQPCGVPCLRTCRNPRGDCLRDVWGLEGCYPKCPPEAPIFDEDKMQCV--ATCPTP 1231
Query: 1395 AVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTA 1454
+ G P G PSD+ Q + L T T
Sbjct: 1232 PLPPRCHVHGKSYRP---GAVVPSDKNCQ------------------SCLCTERGVECTY 1270
Query: 1455 TEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQ 1514
E V Q + + G + T P +P + P
Sbjct: 1271 KAEACVCTYNGQRFHPGDVIYHTTDGTGGCISARCGANGTIERRVYPCSPTTPVPPTTFS 1330
Query: 1515 TPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRTTPP 1574
TP +V + T S + + PP+ +P T G T+P
Sbjct: 1331 FSTPPLVVSSTHTP--------SNGPSSAHTGPPSSAWP------TTAG-------TSPR 1369
Query: 1575 QPSLTASPSSRPVA------SPGAISRSP---TSSGSHKAV--LTPAVTKVISRTGVPQP 1623
TAS S PV SP P T SG + L +V P+
Sbjct: 1370 TRLPTASASLPPVCGEKCLWSPWMDVSRPGRGTDSGDFDTLENLRAHGYRVCES---PRS 1426
Query: 1624 TQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQ---PMGSPASPQ 1680
+ ++ +P PL G + P L R+ E Q P+ S
Sbjct: 1427 VECRAEDAPGVPLRALGQRVQCSPDVGLTCRNREQASGLCYNYQIRVQCCTPLA--CSTS 1484
Query: 1681 PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSG 1740
P + PP ++ T + P TP SLSTA TP ++ +
Sbjct: 1485 SSPAQTTPPTTSKTTETRASGSSAPSSTPGTVSLSTA----RTTPAPGTATSVKKTFSTP 1540
Query: 1741 LPPDTSLPLAKVGTSAPVATPGPKASVITT 1770
PP P+ TS+ ++T P SV+++
Sbjct: 1541 SPP----PVPATSTSS-MSTTTPGTSVVSS 1565
Score = 42.4 bits (98), Expect = 0.007
Identities = 51/186 (27%), Positives = 71/186 (38%), Gaps = 33/186 (17%)
Query: 1451 PVTATEEPVVSPG--------PTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPH 1502
PVT+T PV +P PTQ+T T + + T +P + A H
Sbjct: 1848 PVTST--PVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYA------H 1899
Query: 1503 TPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSS-RSPPAPRFPLMTKAVTV 1561
T ++S P A T P TTR T + SP T S + P+P T +
Sbjct: 1900 TTSTTSAPTARTTSAP--------TTRTT---SASPASTTSGPGNTPSPVPTTSTISAPT 1948
Query: 1562 RGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV- 1620
S P +T P T+S +S P S + S T+S + + T S G
Sbjct: 1949 TSITSAPTTSTTSAP--TSSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPGTT 2006
Query: 1621 --PQPT 1624
P PT
Sbjct: 2007 PSPVPT 2012
Score = 41.2 bits (95), Expect = 0.015
Identities = 73/344 (21%), Positives = 117/344 (34%), Gaps = 47/344 (13%)
Query: 1511 VALQTPTPGMVSGAMETTRVTVI-FAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPV 1569
VA PTP +TT T + A + T +SR P +VT H +
Sbjct: 1687 VATTRPTPHPTGAQTQTTFTTHMPSASTEQPTATSRGGPT------ATSVTQGTHTTPVT 1740
Query: 1570 RTTPPQPSLTA-----SPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPT 1624
R P+ + T PS P + SG +T++
Sbjct: 1741 RNCHPRCTWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRL---------- 1790
Query: 1625 QAQSASSPSTPLTVAGTAAEQVPVSPLATRS------LEIVLSTEKGEAGHSQPMGSPAS 1678
Q ++ S P + G + L R+ ++ L+ E P G P +
Sbjct: 1791 QCRAKSHPEVSIEHLGQVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCPVT 1850
Query: 1679 PQPHPLPSAPP-------------RPAQHTTMATRSPALPPETPAAASLSTATDGLAATP 1725
P PS P + ++ TT+ T S P+T + +T+T
Sbjct: 1851 STPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTAR 1910
Query: 1726 FMSLESTR-----PSQLLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLP 1780
S +TR P+ SG P +T P+ T + T A +T P ++T
Sbjct: 1911 TTSAPTTRTTSASPASTTSG-PGNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTS 1969
Query: 1781 AQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTS 1824
A T S T + + T AP + T+ + +PT+
Sbjct: 1970 APTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPGTTPSPVPTT 2013
Score = 39.3 bits (90), Expect = 0.056
Identities = 47/167 (28%), Positives = 64/167 (38%), Gaps = 21/167 (12%)
Query: 1754 TSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPA----AMTQAHPPTHIAPPAA 1809
TS PV P + +P Q ++ ++T + V T + + T AH + + P A
Sbjct: 1850 TSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTA 1909
Query: 1810 GT--APGLLLGATLPTS-----GVLPVAEGTASMVSV-------VPRKSTTGKVAILSKQ 1855
T AP + P S G P T S +S P STT A S
Sbjct: 1910 RTTSAPTTRTTSASPASTTSGPGNTPSPVPTTSTISAPTTSITSAPTTSTTS--APTSST 1967
Query: 1856 VSLPTSMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTS 1902
S PT+ SA T +P TS P + G T PVPT+
Sbjct: 1968 TSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSG-PGTTPSPVPTT 2013
Score = 35.8 bits (81), Expect = 0.62
Identities = 43/169 (25%), Positives = 59/169 (34%), Gaps = 13/169 (7%)
Query: 1407 TLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQ 1466
T P + S + S + RT T T + P T+ T+T + PT
Sbjct: 1855 TAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTST-----TSAPTA 1909
Query: 1467 TTLQQPLELTASQLPAGPTESPA---SKGVTASLLAIPHTPESSSLPVALQTPTPGMVSG 1523
T P T S PA T P S T S ++ P T +S P T P +
Sbjct: 1910 RTTSAPTTRTTSASPASTTSGPGNTPSPVPTTSTISAP-TTSITSAPTTSTTSAPTSSTT 1968
Query: 1524 AMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRTT 1572
+ TT T S + + + AP T + G PV TT
Sbjct: 1969 SAPTTSTTSAPTSSTTSSPQTSTTSAP----TTSTTSGPGTTPSPVPTT 2013
Score = 34.7 bits (78), Expect = 1.4
Identities = 19/54 (35%), Positives = 26/54 (48%), Gaps = 3/54 (5%)
Query: 1339 RYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCPTPQVLDEVTQR-CVYLEDC 1391
+Y C SPC TC + + + V GC CP VLD++ Q CV + C
Sbjct: 343 QYHECRSPCADTCSNQEHSRACEDHCVAGC--FCPEGTVLDDIGQTGCVPVSKC 394
Score = 32.7 bits (73), Expect = 5.3
Identities = 29/96 (30%), Positives = 40/96 (41%), Gaps = 7/96 (7%)
Query: 1724 TPFMSLESTRPSQLLSGLPPDTS--LPLAKVGTSAPVATPGPKA--SVITTPLQPQATTL 1779
TP S+ P+Q PP TS G+SAP +TPG + + TTP AT++
Sbjct: 1477 TPLACSTSSSPAQTT---PPTTSKTTETRASGSSAPSSTPGTVSLSTARTTPAPGTATSV 1533
Query: 1780 PAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGL 1815
+P P PA T + T + P L
Sbjct: 1534 KKTFSTPSPPPVPATSTSSMSTTTPGTSVVSSKPTL 1569
>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
Length = 5765
Score = 574 bits (1479), Expect = e-163
Identities = 348/1128 (30%), Positives = 539/1128 (47%), Gaps = 72/1128 (6%)
Query: 78 ICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAV 137
+C WG H +TFDG + G +Y + F++Q+ GS P V
Sbjct: 76 VCSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCRAAYEDFNVQLRRG-LVGSRP-----VV 129
Query: 138 SLFFVGEQEIHLAKE---VTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGAS 194
+ + Q + L V G R +LP+ ++Q Y+ V + T W+G
Sbjct: 130 TRVVIKAQGLVLEASNGSVLINGQREELPYSRTGLLVEQSGDYIKVSIRLVLTFLWNGED 189
Query: 195 AVYIKMSPELLGWTHGLCGNNNADPK-DDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPT 253
+ +++ P+ T GLCG+ N P ++ + +LT ++F + + P + P
Sbjct: 190 SALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLTP--LQFGNLQKLDGPTEQC-PD 246
Query: 254 TSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVA 313
LP C + +G+ + LL P F CHA V + A+C DLC+
Sbjct: 247 PLPLPAGNCTDE-----EGICHR--TLLGPAFAECHALVDSTAYLAACAQDLCRCP---T 296
Query: 314 TWCRALAEYARACAQAGRPLQGWRTQL---RQCTVHCKEKAFTYNECIACCPASCHPRAS 370
C EY+R CA AG + WR R C ++ + + EC + C +C
Sbjct: 297 CPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQ-----HQECGSPCTDTCSNPQR 351
Query: 371 CVDSEIACVDGCYCPNG---LIFED---GGCVAPAECPCEFHGTLYPPGSVVKEDCNTCT 424
E CVDGC+CP G + +D GC+ +CPC G Y PG+ C++CT
Sbjct: 352 AQLCEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHGGRTYSPGTSFNTTCSSCT 411
Query: 425 CTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAP 484
C+ G W+C CP CSV G H +T+D + Y C Y+L+K + +FTV +
Sbjct: 412 CSGGLWQCQDLPCPGTCSVQGGAHISTYDEKLYDLHGDCSYVLSKKCADSSFTVLAELRK 471
Query: 485 CGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFL 544
CGL + C+++V++ L + + G V L Y +P + + SS F+
Sbjct: 472 CGLTDNENCLKAVTLSLDGGDTA-IRVQADGGVFLNSIYTQLPLSAAN-ITLFTPSSFFI 529
Query: 545 RVRTNVGVRVLYDREGL-RLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQL 603
V+T +G+++L L ++++++D GLCG FN N DDF + GV E+T
Sbjct: 530 VVQTGLGLQLLVQLVPLMQVFVRLDPAHQGQMCGLCGNFNQNQADDFTALSGVVEATGAA 589
Query: 604 FGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLT--GEMFAPCSAFLSPVPYF 661
F N+WK +AC+ S DPC + ++ +Y+ CS LT F+ C + ++P P+
Sbjct: 590 FANTWKAQAACAN-ARNSFEDPCSLSVENENYARHWCSRLTDPNSAFSRCHSIINPKPFH 648
Query: 662 EQCRRDACRC--GQPCLCATLAHYAHLCRRHGLPV-DFRARLPACAL-SCEASKEYSPCV 717
C D C C + CLCA L+ Y H C G+ + D+R + + +C S+ Y+ V
Sbjct: 649 SNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLSDWRDGVCTKYMQNCPKSQRYAYVV 708
Query: 718 APCGRTCQDLASPEA-CGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQ 776
C TC+ L+ + C V V+GC CP T+L+ A CVP +C C+
Sbjct: 709 DACQPTCRGLSEADVTCSVSFVP-------VDGCTCPAGTFLN-DAGACVPAQECPCYAH 760
Query: 777 GVDYPPGDSDIPSLGHCHCKDGVMSC--DSRAPAAACPAGQVFVNCSDLHTDLELSRERT 834
G PG+ C C G +SC S + C A V+++CS+ +
Sbjct: 761 GTVLAPGEVVHDEGAVCSCTGGKLSCLGASLQKSTGCAAPMVYLDCSNSSAGTPGAE--- 817
Query: 835 CEQQLLNLSVSARGP-CLSGCACPQGLLRHGDA-CFLPEECPCTWKGKEYFPGDQVMSPC 892
C + L V C+SGC CP GL+ G C E+CPC Y PG+ + C
Sbjct: 818 CLRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKPGETIRVDC 877
Query: 893 HTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVK-----STSDVS 947
+TC C+ ++C+ C TC AYGD H+ TFDG + F G+C+ L + +T+ +
Sbjct: 878 NTCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNTTHGT 937
Query: 948 FSVIVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFT 1007
F ++ EN+ C ++G C K I + V + ++ + + D + +G F
Sbjct: 938 FRIVTENIPCGTTGTTCSKAIKLFVESYELILQEGTFKAVARGPGGDPPYKIRY-MGIFL 996
Query: 1008 LVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEF 1067
++ + + WD++T+V ++ ++G++ GLCGNFD IN+ T + + EF
Sbjct: 997 VIE--THGMAVSWDRKTSVFIRLHQDYKGRVCGLCGNFDDNAINDFATRSRSVVGDALEF 1054
Query: 1068 GSSWA-AVECPDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLT 1126
G+SW + CPD L P+D C NP R+ +A+K+CSIL F C VD T +Y C+
Sbjct: 1055 GNSWKLSPSCPDALAPKDPCTANPFRKSWAQKQCSILHGPTFAACRSQVDSTKYYEACVN 1114
Query: 1127 DTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFN 1174
D C C GGDCECFC +V+AYA C G+ V WRTP CP CDF+N
Sbjct: 1115 DACACDSGGDCECFCTAVAAYAQACHDAGLCVSWRTPDTCPLFCDFYN 1162
Score = 237 bits (605), Expect = 1e-61
Identities = 152/481 (31%), Positives = 221/481 (45%), Gaps = 64/481 (13%)
Query: 361 CPASCHPR-ASCVDSEIACVDGCYCPNGLIFE-DGGCVAPAECPCEFHGTLYPPGSVVKE 418
C SCH C + CV GC CP GL+ + GGC+A +CPC + Y PG ++
Sbjct: 818 CLRSCHTLDVGCFSTH--CVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKPGETIRV 875
Query: 419 DCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAK-----SRSS 473
DCNTCTC + +WECS +C C GD HF TFDG RY+F +C+YILA+ + +
Sbjct: 876 DCNTCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNTTH 935
Query: 474 GTFTVTLQNAPCGLNQDGAC------VQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIP 527
GTF + +N PCG V+S +IL + + V GD P
Sbjct: 936 GTFRIVTENIPCGTTGTTCSKAIKLFVESYELILQEGTFKAVARGPGGD----------P 985
Query: 528 PYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQ 587
PY R +FL + T+ G+ V +DR+ +++++ Q + GLCG F+ N
Sbjct: 986 PYKI------RYMGIFLVIETH-GMAVSWDRK-TSVFIRLHQDYKGRVCGLCGNFDDNAI 1037
Query: 588 DDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEM 647
+DF + FGNSWK +C ++ P DPC + S++ + CS+L G
Sbjct: 1038 NDFATRSRSVVGDALEFGNSWKLSPSCPDALA--PKDPCTANPFRKSWAQKQCSILHGPT 1095
Query: 648 FAPCSAFLSPVPYFEQCRRDACRCGQ----PCLCATLAHYAHLCRRHGLPVDFRARLPAC 703
FA C + + Y+E C DAC C C C +A YA C GL V +R C
Sbjct: 1096 FAACRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACHDAGLCVSWRTP-DTC 1154
Query: 704 ALSCE-------ASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGC--ACPP 754
L C+ Y PC APC +TC++ + + G +EGC CPP
Sbjct: 1155 PLFCDFYNPHGGCEWHYQPCGAPCLKTCRNPSGHCLVDLPG---------LEGCYPKCPP 1205
Query: 755 -DTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGH---CHCKDGVMSCDSRAPAAA 810
+ + CV QC C+ + +Y + +P+ + C+C + C A
Sbjct: 1206 SQPFFNEDQMKCVA--QCGCYDKDGNYYDVGARVPTAENCQSCNCTPSGIQCAHSLEACT 1263
Query: 811 C 811
C
Sbjct: 1264 C 1264
Score = 207 bits (528), Expect = 9e-53
Identities = 320/1341 (23%), Positives = 466/1341 (34%), Gaps = 245/1341 (18%)
Query: 1401 EALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVV 1460
E T+ ++ T + +P T LT AA T A P T P
Sbjct: 4361 ETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATGPTAT----PSS 4416
Query: 1461 SPGPTQ--TTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQTPTP 1518
+PG T T L TAS G T +P+S T +L P T + ++P T T
Sbjct: 4417 TPGTTWILTELTTTATTTAS---TGSTATPSSTPGTTWILTEPSTTATVTVPTG-STATA 4472
Query: 1519 GMVSGAMETTRVTVIFAGSPNITVSSRSPP-----APRFPLMTKAVTVRGHGS------- 1566
T V+ A +P +T S +P A P + T S
Sbjct: 4473 SSTQATAGTPHVSTT-ATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSFTAIPSS 4531
Query: 1567 --------LPVRTTPPQPSLTASPSSRP--VASPGAISRSPTSSGSHKAVLTPAVTKVIS 1616
L TTP TA+PSS P V + ++ + T++G+ +V TP+ T +
Sbjct: 4532 SLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTATATTTGATGSVATPSSTPGTA 4591
Query: 1617 RTG-VPQPTQ----AQSASSPSTPLTV-AGTAAEQVPVSPLATRSLEIVLSTEKGEAGHS 1670
T VP T A +SSP T LT + P + T S V + H+
Sbjct: 4592 HTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTTTPTTSGSTVTPSSIPGTTHT 4651
Query: 1671 QPM----------GSPASPQPHPLPSAPPRPAQHTTM----ATRSPALPPETPAAASLST 1716
+ GS A+P S P P+ TT AT S P TP ++
Sbjct: 4652 ARVLTTTTTTVATGSMATPSSSTQTSGTP-PSLTTTATTITATGSTTNPSSTPGTTPITP 4710
Query: 1717 ATDGLAATPFMSLESTRPS---QLLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTPLQ 1773
A TP + S + + LP TS TS TP P +++ TT
Sbjct: 4711 VLTSTATTPAATSSKATSSSSPRTATTLPVLTSTATKSTATSF---TPIPSSTLWTTWTV 4767
Query: 1774 PQATTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGT-------APGLLLGATLPTSGV 1826
P TT P T+S + T + H T + A T P LG T + +
Sbjct: 4768 PAQTTTPMSTMSTI--HTSSTPETTHTSTVLTTTATMTRATNSTATPSSTLGTTRILTEL 4825
Query: 1827 LPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGSAEGGPTELTPATSH------- 1879
A TA+ S ST G IL++ ++ T M + T T+H
Sbjct: 4826 TTTATTTAATGSTATLSSTPGTTWILTEPSTIATVMVPTGSTATASSTLGTAHTPKVVTT 4885
Query: 1880 ----PLTPLVAEPEGAQAGTA-LPVPTSYALSRVSARTAPQDSMLVLLPQ---------- 1924
P P + GT P +L S T + L P
Sbjct: 4886 MATMPTATASTVPSSSTVGTTRTPAVLPSSLPTFSVSTVSSSVLTTLRPTGFPSSHFSTP 4945
Query: 1925 -LAEAHGTSAGP-HLAAEPVDEA----------------------TTEPSGRSAPALSIV 1960
A G P + D A T+ P SAP
Sbjct: 4946 CFCRAFGQFFSPGEVIYNKTDRAGCHFYAVCNQHCDIDRFQGACPTSPPPVSSAP----- 5000
Query: 1961 EGLAEALATTTEANTSTTCVPIAE-------QDCVRHICL-EGQLIRVNQSQHCPQGAAP 2012
L++ + A +P+ + ++C C+ + +++ ++ P+ A
Sbjct: 5001 ------LSSPSPAPGCDNAIPLRQVNETWTLENCTVARCVGDNRVVLLD-----PKPVAN 5049
Query: 2013 PRCGILGLAVRVG--GDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPD 2070
C L ++V C +EC C CS++ + TFDG+ Y+L +
Sbjct: 5050 VTCVNKHLPIKVSDPSQPCDFHYECECICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIH 5109
Query: 2071 EM---LTVHVLD---CKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVW 2124
L++++ + SA P + + VT+ + + +
Sbjct: 5110 ARFGNLSLYLDNHYCTASATAAAARCPRALSIHYKSMDIVLTVTMVHGKEEGLILFDQI- 5168
Query: 2125 PPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQ---------GHGL 2175
PVS GF G + +L + +++ + + G+ + + +A+ G
Sbjct: 5169 -PVSS-GF--SKNGVLVSVLGTTTMRVD-IPALGVSVTFNGQVFQARLPYSLFHNNTEGQ 5223
Query: 2176 CGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSC-------- 2227
CG C + +D +DG+ +D A +W VP S R D C
Sbjct: 5224 CGTCTNNQRDDCLQRDGTTAASCKDMAK---TWLVPDS---------RKDGCWAPTGTPP 5271
Query: 2228 ------------ATTDCSP---CLRMVSNRTFSACHRFVPPESFCELWIRD--TKYVQQP 2270
T C P C M+S + F+ CH VPP F I D ++ P
Sbjct: 5272 TASPAAPVSSTPTPTPCPPQPLCDLMLS-QVFAECHNLVPPGPFFNACISDHCRGRLEVP 5330
Query: 2271 CVALTVYVAMCHKFHVCIEWRRSD--YCPFLCSSDSTYQACVTACEPPKTCQDGILGPLD 2328
C +L Y +C VC +WR + C C Y+ C P TC P
Sbjct: 5331 CQSLEAYAELCRARGVCSDWRGATGGLCDLTCPPTKVYKPCGPI--QPATCNSRNQSP-- 5386
Query: 2329 PEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQ 2388
+ + EGC C E IL H +C+ C C G P+ GE W S+ C +
Sbjct: 5387 --QLEGMAEGCFCPEDQILFNAHMGICVQA--CPCVGPDGFPKFPGERWVSNCQSCVCDE 5442
Query: 2389 CQAPDTIVPVDLGCPSPRPESCLRFGEVALLLP-TKDPCCLGTVCVCNQTLCEGLAPTCR 2447
P+ +P C R G V + P ++PCC TVCVCN T C P C
Sbjct: 5443 GSVSVQCKPLPCDAQG-QPPPCNRPGFVTVTRPRAENPCCPETVCVCNTTTCPQSLPVCP 5501
Query: 2448 PGHRLLTHFQEDSCCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGD 2507
PG + +E CCP++ C P LC + G L CT C GD
Sbjct: 5502 PGQESICTQEEGDCCPTFRCR--PQLCSYN--GTFYGVGATFPGALPCHMCT---CLSGD 5554
Query: 2508 CPDSIPECQEGEALTVHRNTTELCCP--------LYQCVCENFRCPQVQC----GLGTAL 2555
D +CQE NTT CP QC E C Q C G L
Sbjct: 5555 TQDPTVQCQEDAC----NNTT---CPQGFEYKRVAGQCCGE---CVQTACLTPDGQPVQL 5604
Query: 2556 VEVW---SPDRCCPYKSCECD 2573
E W D C Y CE +
Sbjct: 5605 NETWVNSHVDNCTVY-LCEAE 5624
Score = 137 bits (344), Expect = 2e-31
Identities = 116/411 (28%), Positives = 177/411 (43%), Gaps = 42/411 (10%)
Query: 79 CRAWGQHHVETFDGLYYYLSGKGSYTLV----GRHEPEGQSFSIQVHNDPQCGSSPYTCS 134
C A+G H TFDG Y G Y L G + G +F I N P CG++ TCS
Sbjct: 898 CVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNTTHG-TFRIVTENIP-CGTTGTTCS 955
Query: 135 RAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQ-QLAGYVIVRHQSAFTLAWDGA 193
+A+ LF + I + G + G + + G +V ++WD
Sbjct: 956 KAIKLFVESYELI-----LQEGTFKAVARGPGGDPPYKIRYMGIFLVIETHGMAVSWDRK 1010
Query: 194 SAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPT 253
++V+I++ + G GLCGN + + +D T S + D +EF +SW+ P
Sbjct: 1011 TSVFIRLHQDYKGRVCGLCGNFDDNAINDFATRSRSVVGDALEFGNSWKLS-----PSCP 1065
Query: 254 TSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLC--QSMGD 311
+ P+ PC NP +QC L P F AC + V + +C +D C S GD
Sbjct: 1066 DALAPKDPCTA-NPFRKSWAQKQCSILHGPTFAACRSQVDSTKYYEACVNDACACDSGGD 1124
Query: 312 VATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEK------AFTYNECIACCPASC 365
+C A+A YA+AC AG + WRT C + C + Y C A C +C
Sbjct: 1125 CECFCTAVAAYAQACHDAGLCVS-WRTP-DTCPLFCDFYNPHGGCEWHYQPCGAPCLKTC 1182
Query: 366 -HPRASCVDSEIACVDGCY--CPNGL-IFEDGGCVAPAECPC-EFHGTLYPPGSVVK--E 418
+P C+ ++ ++GCY CP F + A+C C + G Y G+ V E
Sbjct: 1183 RNPSGHCL-VDLPGLEGCYPKCPPSQPFFNEDQMKCVAQCGCYDKDGNYYDVGARVPTAE 1241
Query: 419 DCNTCTCTSGKWECSTAVCPAECSVTG------DIHFTTFDGRRYTFPATC 463
+C +C CT +C+ ++ C+ D+ + T DG A C
Sbjct: 1242 NCQSCNCTPSGIQCAHSLEACTCTYEDRTYSYQDVIYNTTDGLGACLIAIC 1292
Score = 132 bits (333), Expect = 4e-30
Identities = 139/540 (25%), Positives = 208/540 (38%), Gaps = 87/540 (16%)
Query: 437 CPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSS--GTFTVTLQNAPCGLNQDGA-- 492
C CS+ G H++TFDG YTF C Y+L + + G ++ L N C + A
Sbjct: 5074 CECICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTASATAAAA 5133
Query: 493 -CVQSVSV-ILHQDPRRQVTLTQAGD--VLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRT 548
C +++S+ D VT+ + ++LFDQ + ++ + + L + +RV
Sbjct: 5134 RCPRALSIHYKSMDIVLTVTMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMRVDI 5193
Query: 549 N-VGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNS 607
+GV V ++ + + L + +T G CGT N +DD L G ++ + +
Sbjct: 5194 PALGVSVTFNGQVFQARLPYSL-FHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKT 5252
Query: 608 W-----------------KTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAP 650
W T S +P+ S PC C ++ ++FA
Sbjct: 5253 WLVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQ--------PLCDLMLSQVFAE 5304
Query: 651 CSAFLSPVPYFEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFR-ARLPACALSCEA 709
C + P P+F C D CR C +L YA LCR G+ D+R A C L+C
Sbjct: 5305 CHNLVPPGPFFNACISDHCRGRLEVPCQSLEAYAELCRARGVCSDWRGATGGLCDLTCPP 5364
Query: 710 SKEYSPCVAPCGRTCQDL-ASPEACGVDGGDDLSRDECVEGCACPPDTYL-DTQADLCVP 767
+K Y PC TC SP+ G+ EGC CP D L + +CV
Sbjct: 5365 TKVYKPCGPIQPATCNSRNQSPQLEGM-----------AEGCFCPEDQILFNAHMGICV- 5412
Query: 768 RNQCSC-HFQGVDYPPGDSDIPSLGHCHCKDGVMS-------CDSRAPAAACPAGQVFVN 819
C C G PG+ + + C C +G +S CD++ C N
Sbjct: 5413 -QACPCVGPDGFPKFPGERWVSNCQSCVCDEGSVSVQCKPLPCDAQGQPPPC-------N 5464
Query: 820 CSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQG-----LLRHGDAC--FLPEE 872
T E C + + + + P S CP G GD C F
Sbjct: 5465 RPGFVTVTRPRAENPCCPETVCVCNTTTCP-QSLPVCPPGQESICTQEEGDCCPTFRCRP 5523
Query: 873 CPCTWKGKEY-----FPGDQVMSPCHTCVCQRG-----SFQCTLHPCASTCTAYGDRHYR 922
C++ G Y FPG PCH C C G + QC C +T G + R
Sbjct: 5524 QLCSYNGTFYGVGATFPG---ALPCHMCTCLSGDTQDPTVQCQEDACNNTTCPQGFEYKR 5580
Score = 92.8 bits (229), Expect = 4e-18
Identities = 102/400 (25%), Positives = 149/400 (37%), Gaps = 48/400 (12%)
Query: 74 ERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYT- 132
E + IC WG H TFDG Y G +Y L+ + S+ + N S+
Sbjct: 5073 ECECICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTASATAAA 5132
Query: 133 --CSRAVSLFFVGEQEIHLAKEVTHG---GMRV--QLPHVMGSAR---LQQLAGYVIVRH 182
C RA+S+ + +I L + HG G+ + Q+P G ++ L + G +R
Sbjct: 5133 ARCPRALSIHYKS-MDIVLTVTMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMRV 5191
Query: 183 Q-SAFTLAWDGASAVYIKMSPELL--GWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVH 239
A ++ V+ P L T G CG + +DD + G +
Sbjct: 5192 DIPALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAK 5251
Query: 240 SW-------------QEQAPNQPPGPTTSSLPRP-PCLQQNPGTMQGVYEQCEALLRPPF 285
+W P P SS P P PC Q C+ +L F
Sbjct: 5252 TWLVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQ---------PLCDLMLSQVF 5302
Query: 286 DACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQL-RQCT 344
CH V P PF +C SD C+ G + C++L YA C G WR C
Sbjct: 5303 AECHNLVPPGPFFNACISDHCR--GRLEVPCQSLEAYAELCRARG-VCSDWRGATGGLCD 5359
Query: 345 VHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCP-NGLIFEDGGCVAPAECPC 403
+ C Y C PA+C+ R E +GC+CP + ++F + CPC
Sbjct: 5360 LTCPPTK-VYKPCGPIQPATCNSRNQSPQLE-GMAEGCFCPEDQILFNAHMGICVQACPC 5417
Query: 404 EF-HGTLYPPGSVVKEDCNTCTCTSG--KWECSTAVCPAE 440
G PG +C +C C G +C C A+
Sbjct: 5418 VGPDGFPKFPGERWVSNCQSCVCDEGSVSVQCKPLPCDAQ 5457
Score = 91.3 bits (225), Expect = 1e-17
Identities = 142/537 (26%), Positives = 207/537 (38%), Gaps = 65/537 (12%)
Query: 1398 VPTEALGNE-TLPPSQGLP--TPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTA 1454
+P+ LG TLP P T S P + E+ T T LT A T A + T
Sbjct: 3072 IPSFTLGTTGTLPEQTTTPMATMSTIHPSSTPETTHTST---VLTTKATTTRATSSMST- 3127
Query: 1455 TEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQ 1514
P +PG T + T + GPT +P+S T +L P T + ++P
Sbjct: 3128 ---PSSTPGTTWILTELTTAATTTAA-TGPTATPSSTPGTTWILTEPSTTATVTVPTG-S 3182
Query: 1515 TPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRTTPP 1574
T T T +V A +P + +SSR+ P+ T +R TTP
Sbjct: 3183 TATASSTRATAGTLKVLTSTATTPTV-ISSRATPSSSPGTATALPALRS-----TATTPT 3236
Query: 1575 QPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTG---VPQPTQAQSASS 1631
S+TA PSS + +S++ T + + + TP+ T T T ++ S
Sbjct: 3237 ATSVTAIPSSSLGTAWTRLSQTTTPTAT-MSTATPSSTPETVHTSTVLTTTTTTTRATGS 3295
Query: 1632 PSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPL-PSAPPR 1690
+TP + GTA + ++ +T G + P SP + P+ S
Sbjct: 3296 VATPSSTPGTA-----------HTTKVPTTTTTGFT--ATPSSSPGTALTPPVWISTTTT 3342
Query: 1691 PAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLA 1750
P T +T +P+ P T A++ T T AT M+ S+ S SG PP SL
Sbjct: 3343 PT--TRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSS--STQTSGTPP--SLTTT 3396
Query: 1751 KVGTSAPVATPGPKASVITTPLQPQAT---TLPAQTLSPVLPFTPAAMTQAHPPTHIAPP 1807
+A +T P ++ TTP+ P T T PA T S V P + T P P
Sbjct: 3397 ATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPP----VPN 3452
Query: 1808 AAGTAPGLLLGATLP----------TSGVLPVAEGT-ASMVSVVPRKSTTGKVAILSKQV 1856
T G L + P TSG+L T S V+ +TT + +
Sbjct: 3453 TTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTPAATTSTTQHSTPAL 3512
Query: 1857 SLPTSMYGSAEGGPTELTPATSH----PLTPLVAEPEGAQAGTALP-VPTSYALSRV 1908
S P + E P+ T H T A P + T LP PTS ++ V
Sbjct: 3513 SSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPSKTRTSTLLPSSPTSAPITTV 3569
Score = 89.0 bits (219), Expect = 6e-17
Identities = 96/386 (24%), Positives = 149/386 (38%), Gaps = 60/386 (15%)
Query: 2482 CRQDQILITGRLGDSCCTSYFCACGDCPDSIPE------CQEGEALTVHRNTTELCCPLY 2535
C +DQIL +G C C C PD P+ ++ + + C
Sbjct: 5397 CPEDQILFNAHMG--ICVQA-CPCVG-PDGFPKFPGERWVSNCQSCVCDEGSVSVQCKPL 5452
Query: 2536 QCVCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIP--VPRCHLWEKSQLDEE 2593
C + P + G T + + + CCP C C+ T P +P C ++S +E
Sbjct: 5453 PCDAQGQPPPCNRPGFVT-VTRPRAENPCCPETVCVCNTTTCPQSLPVCPPGQESICTQE 5511
Query: 2594 FMHSVENVCGCAKYECVKAPVCLSR----ELGVMQPGQTVVELSADGVCHTSRCTT--VL 2647
E C C + C + +C +G PG CH C +
Sbjct: 5512 -----EGDC-CPTFRC-RPQLCSYNGTFYGVGATFPGAL--------PCHMCTCLSGDTQ 5556
Query: 2648 DPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTTSLFLPGA 2707
DP + + C Q +E+ R CCG C +CL P+G
Sbjct: 5557 DPTVQCQEDACNNTTCP------QGFEYKRVAGQCCGECVQTACL--TPDGQPVQL--NE 5606
Query: 2708 SW----IADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTCKED 2763
+W + +C + C + +L P SCP ++ GS+ + GCC +C+ED
Sbjct: 5607 TWVNSHVDNCTVYLCEAEGGVHLLTPQPASCPDVSSCR-----GSLRKT--GCCYSCEED 5659
Query: 2764 GRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVGLQR 2823
SC +V I TI ++ T VN+ C+G CP AS Y+ C CC+E +
Sbjct: 5660 --SC-QVRINTTILWHQ-GCETEVNITFCEGSCPGASKYSAEAQAMQHQCTCCQERRVHE 5715
Query: 2824 RSVQLFCATNATWVPYTVQEPTDCAC 2849
+V L C N + + +T +C C
Sbjct: 5716 ETVPLHC-PNGSAILHTYTHVDECGC 5740
Score = 80.9 bits (198), Expect = 2e-14
Identities = 102/416 (24%), Positives = 154/416 (37%), Gaps = 67/416 (16%)
Query: 2019 GLAVRVGGDRCC---PLWECACR-----CSIFPDLSFVTFDGSHVALFKEAIYILSQSPD 2070
G +RV + C WEC+ R C + D F+TFDG + YIL+Q
Sbjct: 870 GETIRVDCNTCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYC 929
Query: 2071 EMLTVH-VLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSR 2129
T H + N+ C + + ++++ + K PP
Sbjct: 930 GDNTTHGTFRIVTENIPCGTTGTTCSKAIKLFVESYELILQEGTFKAVARGPGGDPP--- 986
Query: 2130 YGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTL 2189
++I G +++++ + + W + + I + K + GLCG D +A ND
Sbjct: 987 --YKIRYMG-IFLVIETHGMAVSWDRKTSVFI-RLHQDYKGRVCGLCGNFDDNAINDFAT 1042
Query: 2190 KDGSVVGGAEDPAPFLDSWQV----PSSLTSVGQTRFRP--DSCATTDCSPCLRMVSNRT 2243
+ SVVG D F +SW++ P +L P S A CS ++ T
Sbjct: 1043 RSRSVVG---DALEFGNSWKLSPSCPDALAPKDPCTANPFRKSWAQKQCS----ILHGPT 1095
Query: 2244 FSACHRFVPPESFCELWIRDTKYVQQP------CVALTVYVAMCHKFHVCIEWRRSDYCP 2297
F+AC V + E + D C A+ Y CH +C+ WR D CP
Sbjct: 1096 FAACRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACHDAGLCVSWRTPDTCP 1155
Query: 2298 FLC-------SSDSTYQACVTACEPPKTCQDGILGPLDPEHCQV---LGEGCV--CSEGT 2345
C + YQ C C KTC++ HC V EGC C
Sbjct: 1156 LFCDFYNPHGGCEWHYQPCGAPC--LKTCRN------PSGHCLVDLPGLEGCYPKCPPSQ 1207
Query: 2346 ILHRRHSALCIPEAKCACTDSMG--------VPRALG-ETWNSSLSGC-CQHQCQA 2391
C+ A+C C D G VP A ++ N + SG C H +A
Sbjct: 1208 PFFNEDQMKCV--AQCGCYDKDGNYYDVGARVPTAENCQSCNCTPSGIQCAHSLEA 1261
Score = 80.1 bits (196), Expect = 3e-14
Identities = 132/523 (25%), Positives = 191/523 (36%), Gaps = 77/523 (14%)
Query: 1501 PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGS-------------PNITVSSRSP 1547
P TP +SS + TP + + TT T GS P + S +
Sbjct: 4232 PSTPATSSTAMPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTAPPPKVLTSPATT 4291
Query: 1548 PAPRFPLMTKAVTVRGHGSLPVRTT----PPQPSLTASPSS-------------RPVASP 1590
P T + + R +LPV T+ S+T PSS PVA+
Sbjct: 4292 PTATSSKATSSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGTLPEQTTTPVATM 4351
Query: 1591 GAISRSPTSSGSH-KAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAG--TAAEQVP 1647
I S T +H VLT T + + P+ + T LT A TAA
Sbjct: 4352 STIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATGPT 4411
Query: 1648 VSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPRPAQHTTMATRSPALPPE 1707
+P +T +L+ A + GS A+P P + +T AT +P
Sbjct: 4412 ATPSSTPGTTWILTELTTTATTTASTGSTATPS--STPGTTWILTEPSTTAT--VTVPTG 4467
Query: 1708 TPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPD------TSLPLAKVGTSAPVATP 1761
+ A AS + AT A TP +S +T P+ S P T+LP + + P AT
Sbjct: 4468 STATASSTQAT---AGTPHVSTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATS 4524
Query: 1762 G---PKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLG 1818
P +S+ TT + TT P T+S P + T T A T G
Sbjct: 4525 FTAIPSSSLGTTWTRLSQTTTPTATMSTATP----SSTPETVHTSTVLTATATTTGATGS 4580
Query: 1819 ATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQ--VSLPTSMYGSAEGGPTELTPA 1876
P+S GTA + VP +TTG A S +L ++ S PT TP
Sbjct: 4581 VATPSS-----TPGTAH-TTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTTTPT 4634
Query: 1877 TS-HPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLAEAHGTSAGP 1935
TS +TP +++P T A + T + + GT
Sbjct: 4635 TSGSTVTP-----------SSIPGTTHTARVLTTTTTTVATGSMATPSSSTQTSGTPPSL 4683
Query: 1936 HLAAEPVDE--ATTEPSGRSAPALSIVEGLAEALATTTEANTS 1976
A + +TT PS S P + + + + ATT A +S
Sbjct: 4684 TTTATTITATGSTTNPS--STPGTTPITPVLTSTATTPAATSS 4724
Score = 76.6 bits (187), Expect = 3e-13
Identities = 118/438 (26%), Positives = 164/438 (37%), Gaps = 44/438 (10%)
Query: 1501 PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSS-RSPPAPRFPLMTKAV 1559
P TP +SS TP + TT T GS S+ R+ P P+ L T A
Sbjct: 1889 PSTPATSSTATPSSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPKV-LTTTAT 1947
Query: 1560 TVRGHGSLPVRTTPPQPSLTASPSSRPVA-SPGAISRSPTSSGS-------HKAVLTPAV 1611
T S ++ P + TA P+ R A +P A S +P S S TP
Sbjct: 1948 TPTVTSSKATPSSSP-GTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPTA 2006
Query: 1612 TKVISRTGVPQPTQAQSASSPSTPLTVAGTAAEQVPVS-PLATRSLEIVLSTEKGEAGHS 1670
T + T S +T T T + P S P + ++ +T G +
Sbjct: 2007 TMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFT--A 2064
Query: 1671 QPMGSPASPQPHPL-PSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSL 1729
P SP + P+ S P T +T +P+ P T A++ T T AT M+
Sbjct: 2065 TPSSSPGTALTPPVWISTTTTPT--TRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMAT 2122
Query: 1730 ESTRPSQLLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQAT---TLPAQTLSP 1786
S+ S SG PP SL +A +T P ++ TTP+ P T T PA T +
Sbjct: 2123 PSS--STQTSGTPP--SLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSNT 2178
Query: 1787 VLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLP----------TSGVLPVAEGT-AS 1835
V P + T P P T G L + P TSG+L T S
Sbjct: 2179 VTPSSALGTTHTPP----VPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPS 2234
Query: 1836 MVSVVPRKSTTGKVAILSKQVSLPTSMYGSAEGGPTELTPATSHPL----TPLVAEPEGA 1891
V+ +TTG + +S P + E P+ T H T A P
Sbjct: 2235 TVTSHTLAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKT 2294
Query: 1892 QAGTALP-VPTSYALSRV 1908
+ T LP PTS ++ V
Sbjct: 2295 RTSTLLPSSPTSAPITTV 2312
Score = 75.1 bits (183), Expect = 9e-13
Identities = 98/389 (25%), Positives = 155/389 (39%), Gaps = 37/389 (9%)
Query: 1431 TPTHRPALTPAAPLTTALNPPVTATE-EPVVSPGPTQTTLQQPLELTASQLPAGPTESP- 1488
T T R A P TTA P VT+++ P SPG T T L P + + P + +P
Sbjct: 1930 TSTLRTAPPPKVLTTTATTPTVTSSKATPSSSPG-TATAL--PALRSTATTPTATSVTPI 1986
Query: 1489 --ASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRS 1546
+S G T + L+ TP ++ + T TP T+ V A + T S +
Sbjct: 1987 PSSSLGTTWTRLSQTTTPTAT-----MSTATPSSTPETAHTSTVLTATATTTGATGSVAT 2041
Query: 1547 PPA-PRFPLMTKAVTVRGHGSLPVRTTPPQPSLT----ASPSSRPVASPGAISRSPTSSG 1601
P + P TK T G ++ P +LT S ++ P ++ S
Sbjct: 2042 PSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGT 2101
Query: 1602 SHKA-VLTPAVTKVISRTGVPQPTQAQSASSP----STPLTVAGTAAEQVPVSPLATRSL 1656
+H A VLT T V + + + Q++ +P +T T+ T + P S T +
Sbjct: 2102 THTATVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPI 2161
Query: 1657 EIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPRPAQHTTMATRSPALPPETP--AAASL 1714
VL+T + +P+S L + P +T T +LPP +P +
Sbjct: 2162 PPVLTTTATTPAATSNTVTPSS----ALGTTHTPPVPNTMATTHGRSLPPSSPHTVRTAW 2217
Query: 1715 STATDGLAATPFMSLESTRPSQLLSGLPPDT--SLPLAKVGTSAPVATPGPKASVITTPL 1772
++AT G+ T ++ ST S L+ T S P + T P + TTP
Sbjct: 2218 TSATSGILGTTHITEPSTVTSHTLAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPG 2277
Query: 1773 QPQATTLPAQTLSP-------VLPFTPAA 1794
AT+ T +P +LP +P +
Sbjct: 2278 HTTATSRTTATATPSKTRTSTLLPSSPTS 2306
Score = 74.7 bits (182), Expect = 1e-12
Identities = 149/651 (22%), Positives = 216/651 (33%), Gaps = 83/651 (12%)
Query: 1399 PTEALGNETLPPSQGLPTPSDEEPQLSQESPRTP-THRPALTPAAPLTTALNPPVTATEE 1457
P+ ALG PP T + L SP T T + T TT + P T T
Sbjct: 3438 PSSALGTTHTPPVPNT-TATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSH 3496
Query: 1458 PVVSPGPTQTTLQQPLELTASQLPAG-PTESPASKGVTASLLAIPHTPESSSLPVALQTP 1516
+P T +T Q +S P+ TESP S G T P +S A TP
Sbjct: 3497 ---TPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTT-----PGHTRGTSRTTATATP 3548
Query: 1517 TPGMVSGAMETTRV-----TVIFAG-SPNITVS-----SRSPPAPRFPLMTKAVTVRGHG 1565
+ S + ++ TV+ G P S S P P +R G
Sbjct: 3549 SKTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAG 3608
Query: 1566 SLPVRT-------TPPQPSLTASPSSRPVASP---GAISRSPTSSGSHKAVLTPAVTKVI 1615
QP + + V G + R+ G K +
Sbjct: 3609 GAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFC 3668
Query: 1616 SRTG-VPQPTQAQSASSPS---------TPLTVAGTAAEQV--PVSPLATRSLEIVLSTE 1663
G P S ++PS T LT T E +P +T +L+
Sbjct: 3669 CNYGHCPSTPATSSTATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEP 3728
Query: 1664 KGEAGHSQPMGSPASPQPHPLPSAPPRPAQHTTM--ATRSPALPPETPAAASLSTATDGL 1721
A + P GS A+ + P + T T S A P +P A+ A
Sbjct: 3729 STTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRST 3788
Query: 1722 AATPFMSLESTRPSQLLSGL---PPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATT 1778
A TP + + PS L T+ P A + T+ P +TP + + +T L ATT
Sbjct: 3789 ATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTP--ETAHTSTVLTTTATT 3846
Query: 1779 LPAQTLSPVLPFTPAAMTQAHPPTHI----------APPAAGTAPGLLLGATLPTSGVLP 1828
A TP PT +P A T P + T PT+
Sbjct: 3847 TRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGST 3906
Query: 1829 VAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGSAEGGPTELTPATSHPLTPLVAEP 1888
V + + P TT + + ++ P+S ++ P+ +T AT+ T P
Sbjct: 3907 VTPSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLITTATTITATGSTTNP 3966
Query: 1889 EGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLAEAHGTSAGPHLAAEPVDEATTE 1948
T +P + + T P + + P + A GT+ P PV T
Sbjct: 3967 SSTPGTTPIPPVLT------TTATTPAATSSTVTP--SSALGTTHTP-----PVPNTTAT 4013
Query: 1949 PSGRSAPALS-------IVEGLAEALATT--TEANTSTTCVPIAEQDCVRH 1990
GRS S + L TT TE +T T+ P A +H
Sbjct: 4014 THGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQH 4064
Score = 73.9 bits (180), Expect = 2e-12
Identities = 147/611 (24%), Positives = 219/611 (35%), Gaps = 107/611 (17%)
Query: 1398 VPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEE 1457
+P+ +LG SQ + +P T LT A T A T
Sbjct: 2543 IPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATTTGATGSVAT---- 2598
Query: 1458 PVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPES-------SSLP 1510
P +PG TT + L T + A P+ SP + ++ TP + SS+P
Sbjct: 2599 PSSTPGTAHTT--KVLTTTTTGFTATPSSSPGTARTLPVWISTTTTPTTRGSTVTPSSIP 2656
Query: 1511 VALQTPTPGMVSGAMETTRVTVIFAGS----PNITVSSRSPPAPRFPLMTKAVTVRGHGS 1566
TPT + TT T + GS + T +S +PP+ L T A T+ GS
Sbjct: 2657 GTTHTPT-------VLTTTTTTVATGSMATPSSSTQTSGTPPS----LTTTATTITATGS 2705
Query: 1567 LPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRT-GVPQPTQ 1625
TT P +++P + P+ P ++ + T+ + + +TP+ + T VP T
Sbjct: 2706 ----TTNP----SSTPGTTPI--PPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTA 2755
Query: 1626 AQ--SASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHP 1683
+ SPS+P TV TA L T + TE P + + Q
Sbjct: 2756 TTHGRSLSPSSPHTVR-TAWTSATSGTLGTTHI-----TEPSTGTSHTPAATTGTTQHST 2809
Query: 1684 LPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPP 1743
+ P P+ T T SP P T + +T+ ATP TR S LL P
Sbjct: 2810 PALSSPHPSSRT---TESPPSPGTTTPGHTRATSRTTATATP----SKTRTSTLLPSSP- 2861
Query: 1744 DTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHPPTH 1803
TSAP+ T V+T +PQ S +P +
Sbjct: 2862 ----------TSAPITT------VVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIR 2905
Query: 1804 IAPPAAGTAP-GLLLGAT----LPTSGVLPVAEGTASMVSVVPRKSTTGKVAI-LSKQVS 1857
A A P GL A +P + V E + V + GK + + ++
Sbjct: 2906 AAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIR 2965
Query: 1858 LPTSMYGSAEGGPTELTPATSHPLTPLVAE------PEGAQAGTALPVPTSYALSRVSAR 1911
+ YG TPATS TP E A T S A+ +
Sbjct: 2966 VFCCNYGHCPS-----TPATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIPSSTPG 3020
Query: 1912 TAPQDSMLVLLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTT 1971
TAP +L T+ P + +AT+ S R+A L + L +T
Sbjct: 3021 TAPPPKVLT---------STATTPTATS---SKATSSSSPRTATTLPV-------LTSTA 3061
Query: 1972 EANTSTTCVPI 1982
+T+T+ PI
Sbjct: 3062 TKSTATSFTPI 3072
Score = 73.2 bits (178), Expect = 4e-12
Identities = 131/571 (22%), Positives = 204/571 (35%), Gaps = 60/571 (10%)
Query: 1398 VPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEE 1457
+P+ +LG SQ + +P T LT A T A T
Sbjct: 4528 IPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTATATTTGATGSVAT---- 4583
Query: 1458 PVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQTPT 1517
P +PG TT + T + A P+ SP + ++ TP +++ + T T
Sbjct: 4584 PSSTPGTAHTT--KVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTTTPTTSGSTVT 4641
Query: 1518 PGMVSGAMETTRV-----TVIFAGS----PNITVSSRSPPAPRFPLMTKAVTVRGHGSL- 1567
P + G T RV T + GS + T +S +PP+ L T A T+ GS
Sbjct: 4642 PSSIPGTTHTARVLTTTTTTVATGSMATPSSSTQTSGTPPS----LTTTATTITATGSTT 4697
Query: 1568 ----PVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLT-PAVTKVISRTGVPQ 1622
TTP P LT++ +P A S TSS S + T P +T +++
Sbjct: 4698 NPSSTPGTTPITPVLTST-----ATTPAATSSKATSSSSPRTATTLPVLTSTATKS---- 4748
Query: 1623 PTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPH 1682
T PS+ L T Q +P++T S ST E H+ + + +
Sbjct: 4749 -TATSFTPIPSSTLWTTWTVPAQT-TTPMSTMSTIHTSSTP--ETTHTSTVLTTTATMTR 4804
Query: 1683 PLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLP 1742
S + T + T AA+ STAT L++TP + T PS + + +
Sbjct: 4805 ATNSTATPSSTLGTTRILTELTTTATTTAATGSTAT--LSSTPGTTWILTEPSTIATVMV 4862
Query: 1743 PDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHPPT 1802
P S A T TP ++ T P +T + T+ TPA + + P
Sbjct: 4863 PTGSTATAS-STLGTAHTPKVVTTMATMPTATASTVPSSSTVGTTR--TPAVLPSSLPTF 4919
Query: 1803 HIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSM 1862
++ ++ TL +G T + + G+V I +K
Sbjct: 4920 SVSTVSSSVL------TTLRPTGFPSSHFSTPCFCRAFGQFFSPGEV-IYNKTDRAGCHF 4972
Query: 1863 YGSAE----------GGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSART 1912
Y PT P +S PL+ P A V ++ L +
Sbjct: 4973 YAVCNQHCDIDRFQGACPTSPPPVSSAPLSSPSPAPGCDNAIPLRQVNETWTLENCTVAR 5032
Query: 1913 APQDSMLVLLPQLAEAHGTSAGPHLAAEPVD 1943
D+ +VLL A+ T HL + D
Sbjct: 5033 CVGDNRVVLLDPKPVANVTCVNKHLPIKVSD 5063
Score = 71.6 bits (174), Expect = 1e-11
Identities = 143/597 (23%), Positives = 209/597 (35%), Gaps = 87/597 (14%)
Query: 1423 QLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPA 1482
+LSQ + T T A + P T + +TAT + G T P +++P
Sbjct: 1997 RLSQTTTPTATMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPT 2056
Query: 1483 ----GPTESPASKGVTASLLAIPHTPESSSLPVAL-QTPTPGMVSGAMET-----TRVTV 1532
G T +P+S TA L P +++ P T TP + G T T T
Sbjct: 2057 TTTTGFTATPSSSPGTA--LTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTT 2114
Query: 1533 IFAGS----PNITVSSRSPPAPRFPLMTKAVTVRGHGSL-----PVRTTPPQPSLTASPS 1583
+ GS + T +S +PP+ L T A T+ GS TTP P LT +
Sbjct: 2115 VATGSMATPSSSTQTSGTPPS----LTTTATTITATGSTTNPSSTPGTTPIPPVLTTT-- 2168
Query: 1584 SRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTAA 1643
+P A S + T S + TP V ++ T ++ SSP T T +A
Sbjct: 2169 ---ATTPAATSNTVTPSSALGTTHTPPVPNTMATT----HGRSLPPSSPHTVRTAWTSAT 2221
Query: 1644 EQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPRPAQHTTMATRSPA 1703
+ + T + T G +Q +PA PHP ++ T SP
Sbjct: 2222 SGILGTTHITEPSTVTSHTLAATTGTTQ-HSTPALSSPHP-----------SSRTTESPP 2269
Query: 1704 LPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAPVATPGP 1763
P T + +T+ ATP TR S LL P TSAP+ T
Sbjct: 2270 SPGTTTPGHTTATSRTTATATP----SKTRTSTLLPSSP-----------TSAPITT--- 2311
Query: 1764 KASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAP-GLLLGAT-- 1820
V+T +PQ S +P + A A P GL A
Sbjct: 2312 ---VVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQ 2368
Query: 1821 --LPTSGVLPVAEGTASMVSVVPRKSTTGKVAI-LSKQVSLPTSMYGSAEGGPT------ 1871
+P + V E + V + GK + + ++ + YG P
Sbjct: 2369 PGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAM 2428
Query: 1872 -ELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLAEAHG 1930
TP T+ LT L ++ + P+S T P + V +P + A
Sbjct: 2429 PSSTPGTTWILTELTTTATTTESTGSTATPSS-TPGTTWILTEPSTTATVTVPTGSTATA 2487
Query: 1931 TSAGPHLAAEPVDEATTEPSGRSAPALSIVE-GLAEAL-----ATTTEANTSTTCVP 1981
+S V T P+ S+ A G A AL TT TS T +P
Sbjct: 2488 SSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIP 2544
Score = 71.2 bits (173), Expect = 1e-11
Identities = 130/553 (23%), Positives = 194/553 (35%), Gaps = 83/553 (15%)
Query: 1501 PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVT 1560
P TP +SS TP + T T GS I S+ P L + A T
Sbjct: 2975 PSTPATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATT 3034
Query: 1561 -------VRGHGSLPVRTTPPQPSLTASPSSRPVASP---------GAISRSPTSSGSHK 1604
S TT P + TA+ S+ +P G + T+ +
Sbjct: 3035 PTATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLPEQTTTPMATM 3094
Query: 1605 AVLTPAVTKVISRTGVPQPTQA---QSASSPSTPLTVAG--------------TAAEQVP 1647
+ + P+ T + T T+A ++ SS STP + G TAA
Sbjct: 3095 STIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTAATTTAATGPT 3154
Query: 1648 VSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPR---PAQHTTMATRSPAL 1704
+P +T +L+ A + P GS A+ + + T S A
Sbjct: 3155 ATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTATTPTVISSRAT 3214
Query: 1705 PPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGL---PPDTSLPLAKVGTSAPVATP 1761
P +P A+ A A TP + + PS L T+ P A + T+ P +TP
Sbjct: 3215 PSSSPGTATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPSSTP 3274
Query: 1762 GPKASVITTPLQPQATTLPAQTLSPVLP-FTPAAMTQAHPPT----------HIAPPAAG 1810
+V T+ + TT T S P TP PT +P A
Sbjct: 3275 ---ETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTAL 3331
Query: 1811 TAPGLLLGATLPT---SGVLPVA-EGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGSA 1866
T P + T PT S V P + GT +V+ +TT + + ++ P+S ++
Sbjct: 3332 TPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTT----VATGSMATPSSSTQTS 3387
Query: 1867 EGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLA 1926
P+ T AT+ T P T +P + + T P + + P +
Sbjct: 3388 GTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLT------TTATTPAATSSTVTP--S 3439
Query: 1927 EAHGTSAGPHLAAEPVDEATTEPSGRSAPALS-------IVEGLAEALATT--TEANTST 1977
A GT+ P PV T GRS P S + L TT TE +T T
Sbjct: 3440 SALGTTHTP-----PVPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVT 3494
Query: 1978 TCVPIAEQDCVRH 1990
+ P A +H
Sbjct: 3495 SHTPAATTSTTQH 3507
Score = 70.9 bits (172), Expect = 2e-11
Identities = 145/613 (23%), Positives = 214/613 (34%), Gaps = 90/613 (14%)
Query: 1407 TLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEE-------PV 1459
T PS L T Q + + T P+ TP T+ + T T P
Sbjct: 3241 TAIPSSSLGTAWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPS 3300
Query: 1460 VSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQTPTPG 1519
+PG TT + T + A P+ SP + ++ TP + T TP
Sbjct: 3301 STPGTAHTT--KVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRG-----STVTPS 3353
Query: 1520 MVSGAMET-----TRVTVIFAGS----PNITVSSRSPPAPRFPLMTKAVTVRGHGSLPVR 1570
+ G T T T + GS + T +S +PP+ L T A T+ GS
Sbjct: 3354 SIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTPPS----LTTTATTITATGS---- 3405
Query: 1571 TTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRT-GVPQPTQAQSA 1629
TT P +++P + P+ P ++ + T+ + + +TP+ + T VP T
Sbjct: 3406 TTNP----SSTPGTTPI--PPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHG 3459
Query: 1630 SS--PSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSA 1687
S PS+P TV TA L T + TE P + ++ Q +
Sbjct: 3460 RSLPPSSPHTVR-TAWTSATSGILGTTHI-----TEPSTVTSHTPAATTSTTQHSTPALS 3513
Query: 1688 PPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSL 1747
P P+ T T SP P T + T+ ATP TR S LL P
Sbjct: 3514 SPHPSSRT---TESPPSPGTTTPGHTRGTSRTTATATP----SKTRTSTLLPSSP----- 3561
Query: 1748 PLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHPPTHIAPP 1807
TSAP+ T V+TT +PQ S +P + A
Sbjct: 3562 ------TSAPITT------VVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGG 3609
Query: 1808 AAGTAP-GLLLGAT----LPTSGVLPVAEGTASMVSVVPRKSTTGKVAI-LSKQVSLPTS 1861
A P GL A +P + V E + V + GK + + ++ +
Sbjct: 3610 AVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCC 3669
Query: 1862 MYGSAEGGPT-------ELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAP 1914
YG P TP T+ LT L ++ + P+S T P
Sbjct: 3670 NYGHCPSTPATSSTATPSSTPGTTWILTKLTTTATTTESTGSTATPSS-TPGTTWILTEP 3728
Query: 1915 QDSMLVLLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVE-GLAEAL-----A 1968
+ V +P + A +S V T P+ S+ A G A AL
Sbjct: 3729 STTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRST 3788
Query: 1969 TTTEANTSTTCVP 1981
TT TS T +P
Sbjct: 3789 ATTPTATSFTAIP 3801
Score = 70.9 bits (172), Expect = 2e-11
Identities = 140/603 (23%), Positives = 210/603 (34%), Gaps = 91/603 (15%)
Query: 1398 VPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEE 1457
+P+ +LG SQ + +P T LT A T A T
Sbjct: 3800 IPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTTRATGSVAT---- 3855
Query: 1458 PVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQTPT 1517
P +PG TT + T + P+ SP + ++ TP +S T T
Sbjct: 3856 PSSTPGTAHTT--KVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSG-----STVT 3908
Query: 1518 PGMVSGAMET-----TRVTVIFAGS----PNITVSSRSPPAPRFPLMTKAVTVRGHGSLP 1568
P V G T T T + GS + T +S +PP+ L+T A T+ GS
Sbjct: 3909 PSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPS----LITTATTITATGS-- 3962
Query: 1569 VRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRT-GVPQPTQAQ 1627
TT P +++P + P+ P ++ + T+ + + +TP+ + T VP T
Sbjct: 3963 --TTNP----SSTPGTTPI--PPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATT 4014
Query: 1628 --SASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLP 1685
+ SPS+P TV TA L T + TE P + + Q
Sbjct: 4015 HGRSLSPSSPHTVR-TAWTSATSGTLGTTHI-----TEPSTGTSHTPAATTGTTQHSTPA 4068
Query: 1686 SAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDT 1745
+ P P+ T T SP P T + +T+ ATP TR S LL P
Sbjct: 4069 LSSPHPSSRT---TESPPSPGTTTPGHTTATSRTTATATP----SKTRTSTLLPSSP--- 4118
Query: 1746 SLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHPPTHIA 1805
TSAP+ T V+TT +PQ S +P + A
Sbjct: 4119 --------TSAPITT------VVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAA 4164
Query: 1806 PPAAGTAP-GLLLGAT----LPTSGVLPVAEGTASMVSVVPRKSTTGKVAI-LSKQVSLP 1859
A P GL A +P + V E + V + GK + + ++ +
Sbjct: 4165 GGAVCEQPLGLECRAQAQPGVPLGELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVF 4224
Query: 1860 TSMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSML 1919
YG TPATS P + P T L + S S T
Sbjct: 4225 CCNYGHCPS-----TPATSSTAMP-SSTPGTTWILTELTTTATTTASTGSTATP------ 4272
Query: 1920 VLLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTC 1979
+ GT+ P + P T S ++ + L +T +T+T+
Sbjct: 4273 ------SSTPGTAPPPKVLTSPATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSV 4326
Query: 1980 VPI 1982
PI
Sbjct: 4327 TPI 4329
Score = 69.7 bits (169), Expect = 4e-11
Identities = 109/448 (24%), Positives = 168/448 (37%), Gaps = 53/448 (11%)
Query: 1397 WVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATE 1456
W+ TE T+ +PT S +Q + TP TTA P VT+++
Sbjct: 3723 WILTEPSTTATVT----VPTGSTATASSTQATAGTPHVS---------TTATTPTVTSSK 3769
Query: 1457 -EPVVSPGPTQTTLQQPLELTASQLPAGPTESPASK-GVTASLLAIPHTPESS-SLPVAL 1513
P SPG T T L + T P+S G T + L+ TP ++ S
Sbjct: 3770 ATPFSSPG-TATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPS 3828
Query: 1514 QTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRT-- 1571
TP S + TT T GS + S P T G P +
Sbjct: 3829 STPETAHTSTVLTTTATTTRATGS---VATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPG 3885
Query: 1572 TPPQPSLTASPSSRPVASPGAISRSPTSSGSH-KAVLTPAVTKVISRTGVPQPTQAQSAS 1630
T P + S ++ P S ++ S +H VLT T V + + + Q++
Sbjct: 3886 TARTPPVWISTTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSG 3945
Query: 1631 SP----STPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPS 1686
+P +T T+ T + P S T + VL+T + +P+S L +
Sbjct: 3946 TPPSLITTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSS----ALGT 4001
Query: 1687 APPRPAQHTTMATRSPALPPETP--AAASLSTATDGLAATPFMSLESTRPSQLLSGLPPD 1744
P +TT T +L P +P + ++AT G T ++ ST S
Sbjct: 4002 THTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSH-------- 4053
Query: 1745 TSLPLAKVGT---SAP-VATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHP 1800
P A GT S P +++P P + +P P TT P T + T A T +
Sbjct: 4054 --TPAATTGTTQHSTPALSSPHPSSRTTESPPSP-GTTTPGHTTA--TSRTTATATPSKT 4108
Query: 1801 PTHIAPPAAGTAPGLLLGATLPTSGVLP 1828
T P++ T+ + T+ T+G P
Sbjct: 4109 RTSTLLPSSPTSAPI---TTVVTTGCEP 4133
Score = 69.3 bits (168), Expect = 5e-11
Identities = 76/304 (25%), Positives = 111/304 (36%), Gaps = 46/304 (15%)
Query: 904 CTLH-PCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDV--SFSVIVENVNCYSS 960
C H C C+ +G HY TFDG + F G C L++ + S+ ++N C +S
Sbjct: 5068 CDFHYECECICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTAS 5127
Query: 961 GMI----CRKFISINVGN---------------SLIVFDDDSGNPSPESFLDDKQEVHTW 1001
C + +SI+ + LI+FD P S K V
Sbjct: 5128 ATAAAARCPRALSIHYKSMDIVLTVTMVHGKEEGLILFDQ-----IPVSSGFSKNGVLVS 5182
Query: 1002 RVGFFTL-VHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNF-----------DLKT 1049
+G T+ V P +++ ++ + + G CG D T
Sbjct: 5183 VLGTTTMRVDIPALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTT 5242
Query: 1050 INEMRTPENLELTNPQEFGSSWAAVECPDTLDPRDMCVLNPLREPFAKKE-CSILLSEVF 1108
+ L WA P T P P P + C ++LS+VF
Sbjct: 5243 AASCKDMAKTWLVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQPLCDLMLSQVF 5302
Query: 1109 EICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWR--TPRLC 1166
CH +V F++ C++D C G E C S+ AYA C GV DWR T LC
Sbjct: 5303 AECHNLVPPGPFFNACISDHC----RGRLEVPCQSLEAYAELCRARGVCSDWRGATGGLC 5358
Query: 1167 PYDC 1170
C
Sbjct: 5359 DLTC 5362
Score = 68.6 bits (166), Expect = 9e-11
Identities = 147/620 (23%), Positives = 222/620 (35%), Gaps = 95/620 (15%)
Query: 1407 TLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQ 1466
T PP+ L T + Q +P+ PT P LT A PP + T P +S G T
Sbjct: 1612 TPPPTTELETATTTTTQALFSTPQ-PTSSPGLTRA--------PPASTTAVPTLSEGLTS 1662
Query: 1467 TTLQQPLELTAS---QLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSG 1523
L + PAG TE P GV S L P S+LP +G
Sbjct: 1663 PRYTSTLGTATTGGPTTPAGSTE-PTVPGVATSTL-----PTRSALPGT---------TG 1707
Query: 1524 AMETTRVTVIFAGSPNITVSSRSPP------APRFPLMTK-AVTVRGHGSLP-VRTTPPQ 1575
++ T R + +P +SR+ P A + PL T A T+ S T+ P+
Sbjct: 1708 SLGTWRPSQPPTLAPTTMATSRARPTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPR 1767
Query: 1576 PSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVP-------QPTQAQS 1628
T SP + S G P K T +GV + +A
Sbjct: 1768 TETTMSPLTNTTTSQGTTRCQP------KCEWTEWFDVDFPTSGVAGGDMETFENIRAAG 1821
Query: 1629 ASSPSTPLTVAGTAAEQVP------VSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPH 1682
P ++ AE P V + T SLE L+ + + M + +
Sbjct: 1822 GKMCWAPKSIE-CRAENYPEVSIDQVGQVLTCSLETGLTCKNEDQTGRFNMCFNYNVRVL 1880
Query: 1683 PLPSAPPRPAQHTTMATRSPALPPET------PAAASLSTATDGLAATPFMSLESTRPSQ 1736
P+ T +T +P+ P T P + +TA+ G ATP +L + P +
Sbjct: 1881 CCDDYSHCPSTPATSSTATPSSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPK 1940
Query: 1737 LLSGLPPDTSLPLAKVGTSAPVATPGPKA------SVITTPLQPQATTLPAQTLSPV--- 1787
+L+ + P + P ++PG S TTP T +P+ +L
Sbjct: 1941 VLT---TTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTR 1997
Query: 1788 --LPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKST 1845
TP A P+ P A T+ +L AT T+G A G+ + S P +
Sbjct: 1998 LSQTTTPTATMSTATPSS-TPETAHTS--TVLTATATTTG----ATGSVATPSSTPGTAH 2050
Query: 1846 TGKVAILSKQ--VSLPTSMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSY 1903
T KV + + P+S G+A P ++ T+ P +++P T
Sbjct: 2051 TTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTP------SSIPGTTHT 2104
Query: 1904 ALSRVSARTAPQDSMLVLLPQLAEAHGTSAGPHLAAEPVDE--ATTEPSGRSAPALSIVE 1961
A + T + + GT A + +TT PS S P + +
Sbjct: 2105 ATVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPS--STPGTTPIP 2162
Query: 1962 GLAEALATTTEANTSTTCVP 1981
+ ATT A TS T P
Sbjct: 2163 PVLTTTATTPAA-TSNTVTP 2181
Score = 68.2 bits (165), Expect = 1e-10
Identities = 92/396 (23%), Positives = 154/396 (38%), Gaps = 32/396 (8%)
Query: 1445 TTALNPPVTATE-EPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHT 1503
+TA P V ++ P SPG T T L + T P+S TA T
Sbjct: 3201 STATTPTVISSRATPSSSPG-TATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTT 3259
Query: 1504 PESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRG 1563
++++ A + TP V + T T + ++ S +P TK T
Sbjct: 3260 TPTATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAH---TTKVPTTTT 3316
Query: 1564 HGSLPVRTTPPQPSLT----ASPSSRPVASPGAISRSPTSSGSHKA-VLTPAVTKVISRT 1618
G ++ P +LT S ++ P ++ S +H A VLT T V + +
Sbjct: 3317 TGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGS 3376
Query: 1619 GVPQPTQAQSASSP----STPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMG 1674
+ Q++ +P +T T+ T + P S T + VL+T +
Sbjct: 3377 MATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTV 3436
Query: 1675 SPASPQPHPLPSAPPRPAQHTTMATRSPALPPETP--AAASLSTATDGLAATPFMSLEST 1732
+P+S L + P +TT T +LPP +P + ++AT G+ T + T
Sbjct: 3437 TPSS----ALGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHI----T 3488
Query: 1733 RPSQLLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTP 1792
PS + S P T+ ++ +++P P + +P P TT P T T
Sbjct: 3489 EPSTVTSHTPAATTSTTQH--STPALSSPHPSSRTTESPPSP-GTTTPGHTRG--TSRTT 3543
Query: 1793 AAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLP 1828
A T + T P++ T+ + T+ T+G P
Sbjct: 3544 ATATPSKTRTSTLLPSSPTSAPI---TTVVTTGCEP 3576
Score = 67.8 bits (164), Expect = 1e-10
Identities = 84/375 (22%), Positives = 135/375 (36%), Gaps = 36/375 (9%)
Query: 2039 CSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVML 2098
CS + D + TFDG Y+ S+ + + +G V+
Sbjct: 77 CSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCRAAYEDFNVQLRRGLVGSRP------VVT 130
Query: 2099 NMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSG 2158
+ A + ++ N V ++ Q P SR G +E +G + + W +
Sbjct: 131 RVVIKAQGLVLEASNGSVLINGQREELPYSRTGLLVEQSGDYIKVSIRLVLTFLW-NGED 189
Query: 2159 LMIVEASKTSKAQGHGLCGICDG-DAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSV 2217
++E Q GLCG +G A N+ + + P F + ++
Sbjct: 190 SALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLT-----PLQFGNLQKLDGPTEQC 244
Query: 2218 GQTRFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDT-KYVQQPCVALTV 2276
P T + C R + F+ CH V ++ +D + PC
Sbjct: 245 PDPLPLPAGNCTDEEGICHRTLLGPAFAECHALVDSTAYLAACAQDLCRCPTCPCATFVE 304
Query: 2277 YVAMC-HKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVL 2335
Y C H WR + CP C + +Q C + C TC + L +HC
Sbjct: 305 YSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPC--TDTCSNPQRAQLCEDHCV-- 360
Query: 2336 GEGCVCSEG---TILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGC-CQ---HQ 2388
+GC C G T+L + C+P +C CT G + G ++N++ S C C Q
Sbjct: 361 -DGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHG-GRTYSPGTSFNTTCSSCTCSGGLWQ 418
Query: 2389 CQAPDTIVPVDLGCP 2403
CQ DL CP
Sbjct: 419 CQ--------DLPCP 425
Score = 67.8 bits (164), Expect = 1e-10
Identities = 103/429 (24%), Positives = 161/429 (37%), Gaps = 62/429 (14%)
Query: 1397 WVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATE 1456
W+ TE T+ +PT S +Q + TP TTA P VT+++
Sbjct: 2466 WILTEPSTTATVT----VPTGSTATASSTQATAGTPHVS---------TTATTPTVTSSK 2512
Query: 1457 -EPVVSPGPTQTTLQQPLELTASQLPAGPTESPASK-GVTASLLAIPHTPESSSLPVALQ 1514
P SPG T T L + T P+S G T + L+ TP ++ +
Sbjct: 2513 ATPFSSPG-TATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTAT-----MS 2566
Query: 1515 TPTPGMVSGAMETTRV---TVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLP--- 1568
T TP + T+ V T G+ + S P T G + P
Sbjct: 2567 TATPSSTPETVHTSTVLTTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSS 2626
Query: 1569 ---VRTTPPQPSLTASPSSR-----PVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV 1620
RT P S T +P++R P + PG + +PT VLT T V + +
Sbjct: 2627 PGTARTLPVWISTTTTPTTRGSTVTPSSIPGT-THTPT-------VLTTTTTTVATGSMA 2678
Query: 1621 PQPTQAQSASSP----STPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSP 1676
+ Q++ +P +T T+ T + P S T + VL+T + +P
Sbjct: 2679 TPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTP 2738
Query: 1677 ASPQPHPLPSAPPRPAQHTTMATRSPALPPETP--AAASLSTATDGLAATPFMSLESTRP 1734
+S L + P +TT T +L P +P + ++AT G T ++ ST
Sbjct: 2739 SS----ALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGT 2794
Query: 1735 SQLLSGLPPDT--SLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSP------ 1786
S + T S P + T P + TTP +AT+ T +P
Sbjct: 2795 SHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRATSRTTATATPSKTRTS 2854
Query: 1787 -VLPFTPAA 1794
+LP +P +
Sbjct: 2855 TLLPSSPTS 2863
Score = 65.9 bits (159), Expect = 6e-10
Identities = 143/620 (23%), Positives = 221/620 (35%), Gaps = 84/620 (13%)
Query: 1405 NETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGP 1464
+ TL + G T P LS SP P+ R +P +P TT TAT + P
Sbjct: 2238 SHTLAATTG--TTQHSTPALS--SPH-PSSRTTESPPSPGTTTPGH-TTATSRTTATATP 2291
Query: 1465 TQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGA 1524
++T T++ LP+ PT +P + VT P S L + P P SG
Sbjct: 2292 SKTR-------TSTLLPSSPTSAPITTVVTMG--CEPQCAWSEWLDYSYPMPGP---SGG 2339
Query: 1525 METTRVTVIFAGSP----NITVSSRSPPAPRFPLMTKAVTVRGHGSLPV----RTTPPQP 1576
T + AG + + R+ P PL V + R +
Sbjct: 2340 DFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKF 2399
Query: 1577 SLTASPSSRPVA-SPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTP 1635
+ + R + G +P +S + TP T +++ T +S S +TP
Sbjct: 2400 KMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPGTTWILTEL-TTTATTTESTGSTATP 2458
Query: 1636 LTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPRPAQHT 1695
+ GT + P T ++ + P GS A+ + P +
Sbjct: 2459 SSTPGTT--WILTEPSTTATVTV-------------PTGSTATASSTQATAGTPHVSTTA 2503
Query: 1696 TM--ATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGL---PPDTSLPLA 1750
T T S A P +P A+ A A TP + + PS L T+ P A
Sbjct: 2504 TTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTA 2563
Query: 1751 KVGTSAPVATPGP--KASVITTPLQPQATT----LPAQT-----LSPVLPFTPAAMTQAH 1799
+ T+ P +TP ++V+TT T P+ T + VL T T A
Sbjct: 2564 TMSTATPSSTPETVHTSTVLTTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFT-AT 2622
Query: 1800 PPTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLP 1859
P + +P A T P + T PT+ V + + P TT + + ++ P
Sbjct: 2623 PSS--SPGTARTLPVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSMATP 2680
Query: 1860 TSMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSML 1919
+S ++ P+ T AT+ T P T +P + + T P +
Sbjct: 2681 SSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLT------TTATTPAATSS 2734
Query: 1920 VLLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALS-------IVEGLAEALATT-- 1970
+ P + A GT+ P PV T GRS S + L TT
Sbjct: 2735 TVTP--SSALGTTHTP-----PVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHI 2787
Query: 1971 TEANTSTTCVPIAEQDCVRH 1990
TE +T T+ P A +H
Sbjct: 2788 TEPSTGTSHTPAATTGTTQH 2807
Score = 61.2 bits (147), Expect = 1e-08
Identities = 63/260 (24%), Positives = 104/260 (40%), Gaps = 22/260 (8%)
Query: 2160 MIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQ 2219
+ V + Q GLCG + + A+D T G V A F ++W+ ++ +
Sbjct: 549 VFVRLDPAHQGQMCGLCGNFNQNQADDFTALSGVVEATG---AAFANTWKAQAACANARN 605
Query: 2220 TRFRPDSCATTDCSP----CLRMVS-NRTFSACHRFVPPESFCELWIRDTKYVQQP---- 2270
+ P S + + + C R+ N FS CH + P+ F + DT ++
Sbjct: 606 SFEDPCSLSVENENYARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNCERSEDCL 665
Query: 2271 CVALTVYVAMCHKFHVCI-EWRRSDYCPFL--CSSDSTYQACVTACEPPKTCQDGILGPL 2327
C AL+ YV C V + +WR ++ C Y V AC+P TC+ +
Sbjct: 666 CAALSSYVHACAAKGVQLSDWRDGVCTKYMQNCPKSQRYAYVVDACQP--TCRGLSEADV 723
Query: 2328 DPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWN--SSLSGCC 2385
V +GC C GT L+ + C+P +C C + G A GE + ++ C
Sbjct: 724 TCSVSFVPVDGCTCPAGTFLN--DAGACVPAQECPCY-AHGTVLAPGEVVHDEGAVCSCT 780
Query: 2386 QHQCQAPDTIVPVDLGCPSP 2405
+ + GC +P
Sbjct: 781 GGKLSCLGASLQKSTGCAAP 800
Score = 59.7 bits (143), Expect = 4e-08
Identities = 82/355 (23%), Positives = 119/355 (33%), Gaps = 53/355 (14%)
Query: 1336 CEWRYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCPTPQ-VLDEVTQRCVYLEDCVEP 1394
CEW Y C +PC +TCR+P D+P +EGC P CP Q +E +CV C +
Sbjct: 1167 CEWHYQPCGAPCLKTCRNPSGHCLVDLPGLEGCYPKCPPSQPFFNEDQMKCVAQCGCYDK 1226
Query: 1395 -------AVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTP-----AA 1442
VPT G+ E RT +++ + A
Sbjct: 1227 DGNYYDVGARVPTAENCQSCNCTPSGIQCAHSLEACTCTYEDRTYSYQDVIYNTTDGLGA 1286
Query: 1443 PLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPH 1502
L T + V PG TT P T + +P S S + S + +
Sbjct: 1287 CLIAICGSNGTIIRKAVACPGTPATT---PFTFTTAWVP----HSTTSPALPVSTVCVRE 1339
Query: 1503 TPESSSLPVALQTPTPGMVSGAMET--------TRVTVIFAGSPNITVSSRSPPAPRFPL 1554
SS P PG+ G ET +V + A + R+ P PL
Sbjct: 1340 VCRWSSWYNG-HRPEPGLGGGDFETFENLRQRGYQVCPVLA-----DIECRAAQLPDMPL 1393
Query: 1555 --MTKAVTVRGHGSLPVRTTPPQPSLTASPSSR----------PVASPGAISRSPTSSGS 1602
+ + V L + P L R P +PG + S+ +
Sbjct: 1394 EELGQQVDCDRMRGLMCANSQQSPPLCHDYELRVLCCEYVPCGPSPAPGTSPQPSLSAST 1453
Query: 1603 HKAVLTPAVTKVISRTGVPQPTQAQSAS-------SPSTPLTVAGTAAEQVPVSP 1650
AV TP T +T + +S + S S P+TV +A P
Sbjct: 1454 EPAVPTPTQTTATEKTTLWVTPSIRSTAALTSQTGSSSGPVTVTPSAPGTTTCQP 1508
Score = 49.7 bits (117), Expect = 4e-05
Identities = 97/478 (20%), Positives = 160/478 (33%), Gaps = 76/478 (15%)
Query: 1562 RGHGSLPVRTTPPQPSLTASPSS-----RPVASPGAISRSPTSSGSHKAVLTPAVTKVIS 1616
RG + P TT + + T + + +P +SPG ++R+P +S + L+ +T
Sbjct: 1607 RGRATTPPPTTELETATTTTTQALFSTPQPTSSPG-LTRAPPASTTAVPTLSEGLTS--- 1662
Query: 1617 RTGVPQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSP 1676
P+ T ++ P T AG+ VP +T L G G +P P
Sbjct: 1663 ----PRYTSTLGTATTGGPTTPAGSTEPTVPGVATSTLPTRSALPGTTGSLGTWRP-SQP 1717
Query: 1677 ASPQPHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATP-----FMSLES 1731
+ P + ++ RP + A++ P P S + + +TP L +
Sbjct: 1718 PTLAPTTMATSRARPTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPRTETTMSPLTN 1777
Query: 1732 TRPSQLLSGLPP--------DTSLPLAKVG-----TSAPVATPGPKASVITTPLQPQATT 1778
T SQ + P D P + V T + G K ++ +A
Sbjct: 1778 TTTSQGTTRCQPKCEWTEWFDVDFPTSGVAGGDMETFENIRAAGGKMCWAPKSIECRAEN 1837
Query: 1779 LPAQTLSPVLPFTPAAM-----------------------------TQAHPPTHIAPPAA 1809
P ++ V ++ +H P+ A +
Sbjct: 1838 YPEVSIDQVGQVLTCSLETGLTCKNEDQTGRFNMCFNYNVRVLCCDDYSHCPSTPATSST 1897
Query: 1810 GT---APGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGSA 1866
T PG T PT+ A T S + T +L+ + PT S+
Sbjct: 1898 ATPSSTPGTTWILTKPTTTATTTA-STGSTATPTSTLRTAPPPKVLTTTATTPT--VTSS 1954
Query: 1867 EGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTS---YALSRVSARTAPQDSMLVLLP 1923
+ P+ +P T+ L L + A + P+P+S +R+S T P +M P
Sbjct: 1955 KATPSS-SPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATP 2013
Query: 1924 QLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 1981
T H + ATT + S S G A T T T P
Sbjct: 2014 S-----STPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATP 2066
Score = 37.7 bits (86), Expect = 0.16
Identities = 25/83 (30%), Positives = 32/83 (38%), Gaps = 10/83 (12%)
Query: 365 CHPRASCVDSEIACVDGC-YCPNG----LIFEDGGCVAPAECP---CEFHGTLYPPGSVV 416
C P CV + C CP G E+G C C C ++GT Y G+
Sbjct: 5480 CCPETVCVCNTTTCPQSLPVCPPGQESICTQEEGDCCPTFRCRPQLCSYNGTFYGVGATF 5539
Query: 417 KE--DCNTCTCTSGKWECSTAVC 437
C+ CTC SG + T C
Sbjct: 5540 PGALPCHMCTCLSGDTQDPTVQC 5562
Score = 35.4 bits (80), Expect = 0.81
Identities = 20/57 (35%), Positives = 30/57 (52%), Gaps = 6/57 (10%)
Query: 1339 RYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCPTPQ---VLDEVTQR-CVYLEDC 1391
++ C SPC TC +P+ A + V+GC CP + VLD++T C+ L C
Sbjct: 334 QHQECGSPCTDTCSNPQRAQLCEDHCVDGC--FCPPGRSCTVLDDITHSGCLPLGQC 388
>gi|161019170 mucin 5AC [Homo sapiens]
Length = 6207
Score = 570 bits (1468), Expect = e-162
Identities = 350/1159 (30%), Positives = 547/1159 (47%), Gaps = 100/1159 (8%)
Query: 78 ICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAV 137
+C WG H +TFDG + G +Y + F++Q+ GS P V
Sbjct: 732 VCSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCRAAYEDFNVQLRRG-LVGSRP-----VV 785
Query: 138 SLFFVGEQEIHLAKE---VTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGAS 194
+ + Q + L V G R +LP+ ++Q Y+ V + T W+G
Sbjct: 786 TRVVIKAQGLVLEASNGSVLINGQREELPYSRTGLLVEQSGDYIKVSIRLVLTFLWNGED 845
Query: 195 AVYIKMSPELLGWTHGLCGNNNADPK-DDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPT 253
+ +++ P+ T GLCG+ N P ++ + +LT ++F + + P + P
Sbjct: 846 SALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLTP--LQFGNLQKLDGPTEQC-PD 902
Query: 254 TSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVA 313
LP C + +G+ + LL P F CHA V + A+C DLC+
Sbjct: 903 PLPLPAGNCTDE-----EGICHR--TLLGPAFAECHALVDSTAYLAACAQDLCRCP---T 952
Query: 314 TWCRALAEYARACAQAGRPLQGWRTQL---RQCTVHCKEKAFTYNECIACCPASCHPRAS 370
C EY+R CA AG + WR R C ++ + + EC + C +C
Sbjct: 953 CPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQ-----HQECGSPCTDTCSNPQR 1007
Query: 371 CVDSEIACVDGCYCPNG---LIFED---GGCVAPAECPCEFHGTLYPPGSVVKEDCNTCT 424
E CVDGC+CP G + +D GC+ +CPC G Y PG+ C++CT
Sbjct: 1008 AQLCEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHGGRTYSPGTSFNTTCSSCT 1067
Query: 425 CTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAP 484
C+ G W+C CP CSV G H +T+D + Y C Y+L+K + +FTV +
Sbjct: 1068 CSGGLWQCQDLPCPGTCSVQGGAHISTYDEKLYDLHGDCSYVLSKKCADSSFTVLAELRK 1127
Query: 485 CGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFL 544
CGL + C+++V++ L + + G V L Y + P + + SS F+
Sbjct: 1128 CGLTDNENCLKAVTLSL-DGGDTAIRVQADGGVFLNSIYTQL-PLSAANITLFTPSSFFI 1185
Query: 545 RVRTNVGVRVLYDREGL-RLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQL 603
V+T +G+++L L ++++++D GLCG FN N DDF + GV E+T
Sbjct: 1186 VVQTGLGLQLLVQLVPLMQVFVRLDPAHQGQMCGLCGNFNQNQADDFTALSGVVEATGAA 1245
Query: 604 FGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLT--GEMFAPCSAFLSPVPYF 661
F N+WK +AC+ S DPC + ++ +Y+ CS LT F+ C + ++P P+
Sbjct: 1246 FANTWKAQAACAN-ARNSFEDPCSLSVENENYARHWCSRLTDPNSAFSRCHSIINPKPFH 1304
Query: 662 EQCRRDACRC--GQPCLCATLAHYAHLCRRHGLPV-DFRARLPACAL-SCEASKEYSPCV 717
C D C C + CLCA L+ Y H C G+ + D+R + + +C S+ Y+ V
Sbjct: 1305 SNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLSDWRDGVCTKYMQNCPKSQRYAYVV 1364
Query: 718 APCGRTCQDLASPE-ACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQ 776
C TC+ L+ + C V V+GC CP T+L+ A CVP +C C+
Sbjct: 1365 DACQPTCRGLSEADVTCSVSFVP-------VDGCTCPAGTFLN-DAGACVPAQECPCYAH 1416
Query: 777 GVDYPPGDSDIPSLGHCHCKDGVMSC--DSRAPAAACPAGQVFVNCSDLHTDLELSRERT 834
G PG+ C C G +SC S + C A V+++CS+ +
Sbjct: 1417 GTVLAPGEVVHDEGAVCSCTGGKLSCLGASLQKSTGCAAPMVYLDCSNSSAG---TPGAE 1473
Query: 835 CEQQLLNLSVSARGP-CLSGCACPQGLLRHGD-ACFLPEECPCTWKGKEYFPGDQVMSPC 892
C + L V C+SGC CP GL+ G C E+CPC Y PG+ + C
Sbjct: 1474 CLRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKPGETIRVDC 1533
Query: 893 HTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVK-----STSDVS 947
+TC C+ ++C+ C TC AYGD H+ TFDG + F G+C+ L + +T+ +
Sbjct: 1534 NTCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNTTHGT 1593
Query: 948 FSVIVENVNCYSSGMICRK----FISINVGNSLIVFDDDSGNPSP-ESFLDDKQEV---- 998
F ++ EN+ C ++G C K F+ + ++ D + P+P E+ + +Q +
Sbjct: 1594 FRIVTENIPCGTTGTTCSKAIKLFVEVRTAPAVSTPDPAANEPAPREASVGFRQRLPPLQ 1653
Query: 999 ---------------------HTWRVGFFTLVHFPQEH-ITLLWDQRTTVHVQAGPQWQG 1036
+++ + + + H + + WD++T+V ++ ++G
Sbjct: 1654 SYELILQEGTFKAVARGPGGDPPYKIRYMGIFLVIETHGMAVSWDRKTSVFIRLHQDYKG 1713
Query: 1037 QLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSW-AAVECPDTLDPRDMCVLNPLREPF 1095
++ GLCGNFD IN+ T + + EFG+SW + CPD L P+D C NP R+ +
Sbjct: 1714 RVCGLCGNFDDNAINDFATRSRSVVGDALEFGNSWKLSPSCPDALAPKDPCTANPFRKSW 1773
Query: 1096 AKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHG 1155
A+K+CSIL F C VD T +Y C+ D C C GGDCECFC +V+AYA C G
Sbjct: 1774 AQKQCSILHGPTFAACRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACHDAG 1833
Query: 1156 VAVDWRTPRLCPYDCDFFN 1174
+ V WRTP CP CDF+N
Sbjct: 1834 LCVSWRTPDTCPLFCDFYN 1852
Score = 264 bits (675), Expect = 8e-70
Identities = 180/565 (31%), Positives = 268/565 (47%), Gaps = 29/565 (5%)
Query: 78 ICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAV 137
+C WG H +TFDG + G +Y + F+IQ+ + S+ T SR
Sbjct: 80 VCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQE--SAAPTLSRV- 136
Query: 138 SLFFVGEQEIHLAK-EVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAV 196
L V I L K V G V LP +QQ + Y V + L W+ ++
Sbjct: 137 -LMKVDGVVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKVEARLGLVLMWNHDDSL 195
Query: 197 YIKMSPELLGWTHGLCGNNNADPK-DDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTS 255
+++ + T GLCG+ N P +L++ + KLT +EF + Q + P
Sbjct: 196 LLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTP--MEFGNL---QKMDDPTEQCQD 250
Query: 256 SLPRPPCLQQNPGTMQGVYEQCEALLRPP-FDACHAYVSPLPFTASCTSDLC--QSMGDV 312
+P PP +N T G+ CE LL F C A V + +C DLC + +
Sbjct: 251 PVPEPP---RNCSTGFGI---CEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLL 304
Query: 313 ATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCV 372
+ C LAEY+R C AG Q WR C C Y+EC + C +C +
Sbjct: 305 SCVCHTLAEYSRQCTHAGGLPQDWRGP-DFCPQKCPNN-MQYHECRSPCADTCSNQEHSR 362
Query: 373 DSEIACVDGCYCPNGLIFED---GGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGK 429
E CV GC+CP G + +D GCV ++C C ++G Y PG+ DC CTC+ G+
Sbjct: 363 ACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYSTDCTNCTCSGGR 422
Query: 430 WECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQ 489
W C CP CSV G HF+TFDG++YT C Y+L K S FTV + CGL
Sbjct: 423 WSCQEVPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCGLTD 482
Query: 490 DGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTN 549
C++SV++ L D + V + +A + +Q P + I R S+ F+ +T+
Sbjct: 483 SETCLKSVTLSL--DGAQTVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTS 540
Query: 550 VGVRV-LYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSW 608
+G+++ L ++L++Q+ + T GLCG FN DDF + GV E+T F N++
Sbjct: 541 LGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTF 600
Query: 609 KTLSACSPLVSGSPLDPCDVHLQAA 633
KT +AC P + S DPC + ++ A
Sbjct: 601 KTQAAC-PNIRNSFEDPCSLSVENA 624
Score = 231 bits (589), Expect = 8e-60
Identities = 152/500 (30%), Positives = 233/500 (46%), Gaps = 68/500 (13%)
Query: 361 CPASCHPR-ASCVDSEIACVDGCYCPNGLIFE-DGGCVAPAECPCEFHGTLYPPGSVVKE 418
C SCH C + CV GC CP GL+ + GGC+A +CPC + Y PG ++
Sbjct: 1474 CLRSCHTLDVGCFSTH--CVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKPGETIRV 1531
Query: 419 DCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAK-----SRSS 473
DCNTCTC + +WECS +C C GD HF TFDG RY+F +C+YILA+ + +
Sbjct: 1532 DCNTCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNTTH 1591
Query: 474 GTFTVTLQNAPCGLNQDGAC--------VQSVSVILHQDP--------------RRQVTL 511
GTF + +N PCG V++ + DP R+++
Sbjct: 1592 GTFRIVTENIPCGTTGTTCSKAIKLFVEVRTAPAVSTPDPAANEPAPREASVGFRQRLPP 1651
Query: 512 TQAGDVLLFD-QYKIIP--PYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVD 568
Q+ +++L + +K + P D ++IR + +FL + T+ G+ V +DR+ +++++
Sbjct: 1652 LQSYELILQEGTFKAVARGPGGDPPYKIRYM-GIFLVIETH-GMAVSWDRK-TSVFIRLH 1708
Query: 569 QRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDV 628
Q + GLCG F+ N +DF + FGNSWK +C + +P DPC
Sbjct: 1709 QDYKGRVCGLCGNFDDNAINDFATRSRSVVGDALEFGNSWKLSPSCPDAL--APKDPCTA 1766
Query: 629 HLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQ----PCLCATLAHYA 684
+ S++ + CS+L G FA C + + Y+E C DAC C C C +A YA
Sbjct: 1767 NPFRKSWAQKQCSILHGPTFAACRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYA 1826
Query: 685 HLCRRHGLPVDFRARLPACALSCE-------ASKEYSPCVAPCGRTCQDLASPEACGVDG 737
C GL V +R C L C+ Y PC APC +TC++ + + G
Sbjct: 1827 QACHDAGLCVSWRTP-DTCPLFCDFYNPHGGCEWHYQPCGAPCLKTCRNPSGHCLVDLPG 1885
Query: 738 GDDLSRDECVEGC--ACPP-DTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGH-- 792
+EGC CPP + + CV QC C+ + +Y + +P+ +
Sbjct: 1886 ---------LEGCYPKCPPSQPFFNEDQMKCVA--QCGCYDKDGNYYDVGARVPTAENCQ 1934
Query: 793 -CHCKDGVMSCDSRAPAAAC 811
C+C + C A C
Sbjct: 1935 SCNCTPSGIQCAHSLEACTC 1954
Score = 149 bits (376), Expect = 4e-35
Identities = 107/380 (28%), Positives = 163/380 (42%), Gaps = 35/380 (9%)
Query: 441 CSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSG--TFTVTLQNAPCGLNQDGACVQSVS 498
CS G H+ TFDG + FP C Y+ ++ + F + L+ + Q+ A
Sbjct: 81 CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRS-----QESAAPTLSR 135
Query: 499 VILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDR 558
V++ D V + +L + + ++ P++ I++ SS + +V +G+ ++++
Sbjct: 136 VLMKVDG---VVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSS-YTKVEARLGLVLMWNH 191
Query: 559 EGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLV 618
+ L L++D ++ T GLCG FNG L + TP FGN K
Sbjct: 192 DD-SLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNT-KLTPMEFGNLQKMDDPTEQCQ 249
Query: 619 SGSPLDPCDVHLQAASYSVQACS-VLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQ---- 673
P P + S C +L G++F+ C A + Y E CR+D C C
Sbjct: 250 DPVPEPP-----RNCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLL 304
Query: 674 PCLCATLAHYAHLC-RRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEA 732
C+C TLA Y+ C GLP D+R C C + +Y C +PC TC + A
Sbjct: 305 SCVCHTLAEYSRQCTHAGGLPQDWRGP-DFCPQKCPNNMQYHECRSPCADTCSNQEHSRA 363
Query: 733 CGVDGGDDLSRDECVEGCACPPDTYLDTQADL-CVPRNQCSCHFQGVDYPPGDSDIPSLG 791
C D CV GC CP T LD CVP ++C+C + G Y PG +
Sbjct: 364 C---------EDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYSTDCT 414
Query: 792 HCHCKDGVMSCDSRAPAAAC 811
+C C G SC C
Sbjct: 415 NCTCSGGRWSCQEVPCPGTC 434
Score = 144 bits (363), Expect = 1e-33
Identities = 127/443 (28%), Positives = 162/443 (36%), Gaps = 83/443 (18%)
Query: 2174 GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSC------ 2227
G CG C + +D +DG+ +D A +W VP S R D C
Sbjct: 5556 GQCGTCTNNQRDDCLQRDGTTAASCKDMAK---TWLVPDS---------RKDGCWAPTGT 5603
Query: 2228 --------------ATTDCSP---CLRMVSNRTFSACHRFVPPESFCELWIRD--TKYVQ 2268
T C P C M+S + F+ CH VPP F I D ++
Sbjct: 5604 PPTASPAAPVSSTPTPTPCPPQPLCDLMLS-QVFAECHNLVPPGPFFNACISDHCRGRLE 5662
Query: 2269 QPCVALTVYVAMCHKFHVCIEWRRSD--YCPFLCSSDSTYQACVTACEPPKTCQDGILGP 2326
PC +L Y +C VC +WR + C C Y+ C P TC P
Sbjct: 5663 VPCQSLEAYAELCRARGVCSDWRGATGGLCDLTCPPTKVYKPCGPI--QPATCNSRNQSP 5720
Query: 2327 LDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQ 2386
+ + EGC C E IL H +C+ C C G P+ GE W S+ C
Sbjct: 5721 ----QLEGMAEGCFCPEDQILFNAHMGICVQA--CPCVGPDGFPKFPGERWVSNCQSCVC 5774
Query: 2387 HQCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLP-TKDPCCLGTVCVCNQTLCEGLAPT 2445
+ P+ +P C R G V + P ++PCC TVCVCN T C P
Sbjct: 5775 DEGSVSVQCKPLPCDAQG-QPPPCNRPGFVTVTRPRAENPCCPETVCVCNTTTCPQSLPV 5833
Query: 2446 CRPGHRLLTHFQEDSCCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCAC 2505
C PG + +E CCP++ C P LC + G L CT C
Sbjct: 5834 CPPGQESICTQEEGDCCPTFRCR--PQLCSYN--GTFYGVGATFPGALPCHMCT---CLS 5886
Query: 2506 GDCPDSIPECQEGEALTVHRNTTELCCP--------LYQCVCENFRCPQVQC----GLGT 2553
GD D +CQE NTT CP QC E C Q C G
Sbjct: 5887 GDTQDPTVQCQEDAC----NNTT---CPQGFEYKRVAGQCCGE---CVQTACLTPDGQPV 5936
Query: 2554 ALVEVW---SPDRCCPYKSCECD 2573
L E W D C Y CE +
Sbjct: 5937 QLNETWVNSHVDNCTVY-LCEAE 5958
Score = 134 bits (337), Expect = 1e-30
Identities = 147/579 (25%), Positives = 220/579 (37%), Gaps = 108/579 (18%)
Query: 402 PCEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTAVCPAE--CSVTGDIHFTTFDGRRYTF 459
PC+FH +C C C G+ + P CS+ G H++TFDG YTF
Sbjct: 5386 PCDFH-----------YECE-CECVGGR-----GITPGAGICSMWGGSHYSTFDGTSYTF 5428
Query: 460 PATCQYILAKSRSS--GTFTVTLQNAPCGLNQDGA-----CVQSVSV-ILHQDPRRQVTL 511
C Y+L + + G ++ L N C + A C +++S+ D VT+
Sbjct: 5429 RGNCTYVLMREIHARFGNLSLYLDNHYCTASATAAAAAARCPRALSIHYKSMDIVLTVTM 5488
Query: 512 TQAGD--VLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTN-VGVRVLYDREGLRLYLQVD 568
+ ++LFDQ + ++ + + L + +RV +GV V ++ + + L
Sbjct: 5489 VHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMRVDIPALGVSVTFNGQVFQARLPYS 5548
Query: 569 QRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSW-----------------KTL 611
+ +T G CGT N +DD L G ++ + +W T
Sbjct: 5549 L-FHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTWLVPDSRKDGCWAPTGTPPTA 5607
Query: 612 SACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRC 671
S +P+ S PC C ++ ++FA C + P P+F C D CR
Sbjct: 5608 SPAAPVSSTPTPTPCPPQ--------PLCDLMLSQVFAECHNLVPPGPFFNACISDHCRG 5659
Query: 672 GQPCLCATLAHYAHLCRRHGLPVDFR-ARLPACALSCEASKEYSPCVAPCGRTCQDL-AS 729
C +L YA LCR G+ D+R A C L+C +K Y PC TC S
Sbjct: 5660 RLEVPCQSLEAYAELCRARGVCSDWRGATGGLCDLTCPPTKVYKPCGPIQPATCNSRNQS 5719
Query: 730 PEACGVDGGDDLSRDECVEGCACPPDTYL-DTQADLCVPRNQCSC-HFQGVDYPPGDSDI 787
P+ G+ EGC CP D L + +CV C C G PG+ +
Sbjct: 5720 PQLEGM-----------AEGCFCPEDQILFNAHMGICV--QACPCVGPDGFPKFPGERWV 5766
Query: 788 PSLGHCHCKDGVMS-------CDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLL 840
+ C C +G +S CD++ C N T E C + +
Sbjct: 5767 SNCQSCVCDEGSVSVQCKPLPCDAQGQPPPC-------NRPGFVTVTRPRAENPCCPETV 5819
Query: 841 NLSVSARGPCLSGCACPQG-----LLRHGDAC--FLPEECPCTWKGKEY-----FPGDQV 888
+ + P S CP G GD C F C++ G Y FPG
Sbjct: 5820 CVCNTTTCP-QSLPVCPPGQESICTQEEGDCCPTFRCRPQLCSYNGTFYGVGATFPG--- 5875
Query: 889 MSPCHTCVCQRG-----SFQCTLHPCASTCTAYGDRHYR 922
PCH C C G + QC C +T G + R
Sbjct: 5876 ALPCHMCTCLSGDTQDPTVQCQEDACNNTTCPQGFEYKR 5914
Score = 133 bits (334), Expect = 3e-30
Identities = 121/444 (27%), Positives = 183/444 (41%), Gaps = 74/444 (16%)
Query: 79 CRAWGQHHVETFDGLYYYLSGKGSYTLV----GRHEPEGQSFSIQVHNDPQCGSSPYTCS 134
C A+G H TFDG Y G Y L G + G +F I N P CG++ TCS
Sbjct: 1554 CVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNTTHG-TFRIVTENIP-CGTTGTTCS 1611
Query: 135 RAVSLFFVGEQEIHLAKEVTHG--------------GMRVQLPHVMGSARLQQ------- 173
+A+ LF E+ A V+ G R +LP + + Q
Sbjct: 1612 KAIKLFV----EVRTAPAVSTPDPAANEPAPREASVGFRQRLPPLQSYELILQEGTFKAV 1667
Query: 174 -------------LAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPK 220
G +V ++WD ++V+I++ + G GLCGN + +
Sbjct: 1668 ARGPGGDPPYKIRYMGIFLVIETHGMAVSWDRKTSVFIRLHQDYKGRVCGLCGNFDDNAI 1727
Query: 221 DDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEAL 280
+D T S + D +EF +SW+ P + P+ PC NP +QC L
Sbjct: 1728 NDFATRSRSVVGDALEFGNSWK-----LSPSCPDALAPKDPC-TANPFRKSWAQKQCSIL 1781
Query: 281 LRPPFDACHAYVSPLPFTASCTSD--LCQSMGDVATWCRALAEYARACAQAGRPLQGWRT 338
P F AC + V + +C +D C S GD +C A+A YA+AC AG + WRT
Sbjct: 1782 HGPTFAACRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACHDAGLCV-SWRT 1840
Query: 339 QLRQCTVHCK------EKAFTYNECIACCPASC-HPRASCVDSEIACVDGCY--C-PNGL 388
C + C + Y C A C +C +P C+ ++ ++GCY C P+
Sbjct: 1841 P-DTCPLFCDFYNPHGGCEWHYQPCGAPCLKTCRNPSGHCL-VDLPGLEGCYPKCPPSQP 1898
Query: 389 IFEDGGCVAPAECPC-EFHGTLYPPGSVV--KEDCNTCTCTSGKWECSTAVCPAECSVTG 445
F + A+C C + G Y G+ V E+C +C CT +C+ ++ C+
Sbjct: 1899 FFNEDQMKCVAQCGCYDKDGNYYDVGARVPTAENCQSCNCTPSGIQCAHSLEACTCTYED 1958
Query: 446 ------DIHFTTFDGRRYTFPATC 463
D+ + T DG A C
Sbjct: 1959 RTYSYQDVIYNTTDGLGACLIAIC 1982
Score = 101 bits (251), Expect = 1e-20
Identities = 103/408 (25%), Positives = 156/408 (38%), Gaps = 67/408 (16%)
Query: 724 CQDLAS--PEACGVDGG--DDLSRDECVEGCACPPD--TYLDT-QADLCVPRN----QCS 772
CQD P C G ++L + GC D +YL+ + DLC + C
Sbjct: 248 CQDPVPEPPRNCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLLSCV 307
Query: 773 CHFQGVDYP---------PGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDL 823
CH +Y P D P C + + + R+P C+D
Sbjct: 308 CHTLA-EYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSP------------CADT 354
Query: 824 HTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHG---DACFLPEECPCTWKGK 880
++ E SR CE C++GC CP+G + C +C C + G
Sbjct: 355 CSNQEHSR--ACEDH-----------CVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGA 401
Query: 881 EYFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLV 940
Y PG + C C C G + C PC TC+ G H+ TFDG + G C L
Sbjct: 402 AYAPGATYSTDCTNCTCSGGRWSCQEVPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLT 461
Query: 941 KSTSDVSFSVIVENVNC-YSSGMICRKFISINV-GNSLIVFDDDSGNPSPESFLD----- 993
K +F+V+ E C + C K +++++ G +V SG E FL+
Sbjct: 462 KPCDSSAFTVLAELRRCGLTDSETCLKSVTLSLDGAQTVVVIKASG----EVFLNQIYTQ 517
Query: 994 ---DKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVH--VQAGPQWQGQLAGLCGNFDLK 1048
V +R F ++ + L T+ +Q P+ +GQ GLCGNF+
Sbjct: 518 LPISAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSI 577
Query: 1049 TINEMRTPEN-LELTNPQEFGSSWAAVECPDTLDP-RDMCVLNPLREP 1094
++ RT +E T F + CP+ + D C L+ P
Sbjct: 578 QADDFRTLSGVVEATAAAFFNTFKTQAACPNIRNSFEDPCSLSVENAP 625
Score = 91.7 bits (226), Expect = 1e-17
Identities = 100/398 (25%), Positives = 147/398 (36%), Gaps = 50/398 (12%)
Query: 78 ICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHN-----DPQCGSSPYT 132
IC WG H TFDG Y G +Y L+ + S+ + N ++
Sbjct: 5409 ICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTASATAAAAAAR 5468
Query: 133 CSRAVSLFFVGEQEIHLAKEVTHG---GMRV--QLPHVMGSAR---LQQLAGYVIVRHQ- 183
C RA+S+ + +I L + HG G+ + Q+P G ++ L + G +R
Sbjct: 5469 CPRALSIHYKS-MDIVLTVTMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMRVDI 5527
Query: 184 SAFTLAWDGASAVYIKMSPELL--GWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSW 241
A ++ V+ P L T G CG + +DD + G + +W
Sbjct: 5528 PALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTW 5587
Query: 242 -------------QEQAPNQPPGPTTSSLPRP-PCLQQNPGTMQGVYEQCEALLRPPFDA 287
P P SS P P PC Q C+ +L F
Sbjct: 5588 LVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQ---------PLCDLMLSQVFAE 5638
Query: 288 CHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQL-RQCTVH 346
CH V P PF +C SD C+ G + C++L YA C G WR C +
Sbjct: 5639 CHNLVPPGPFFNACISDHCR--GRLEVPCQSLEAYAELCRARG-VCSDWRGATGGLCDLT 5695
Query: 347 CKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCP-NGLIFEDGGCVAPAECPCEF 405
C Y C PA+C+ R E +GC+CP + ++F + CPC
Sbjct: 5696 CPPTK-VYKPCGPIQPATCNSRNQSPQLE-GMAEGCFCPEDQILFNAHMGICVQACPCVG 5753
Query: 406 -HGTLYPPGSVVKEDCNTCTCTSG--KWECSTAVCPAE 440
G PG +C +C C G +C C A+
Sbjct: 5754 PDGFPKFPGERWVSNCQSCVCDEGSVSVQCKPLPCDAQ 5791
Score = 91.3 bits (225), Expect = 1e-17
Identities = 137/521 (26%), Positives = 192/521 (36%), Gaps = 74/521 (14%)
Query: 1407 TLPPSQGLPTPSD-----EEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVVS 1461
T PP + L +P+ S SPRT T P LT A +TA + T P +
Sbjct: 4748 TAPPPKVLTSPATTPTATSSKATSSSSPRTATTLPVLTSTATKSTA----TSVTPIPSST 4803
Query: 1462 PGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMV 1521
G T T +Q A+ P+ +P + T+++L T ++ + + TPG
Sbjct: 4804 LGTTGTLPEQTTTPVATMSTIHPSSTPETTH-TSTVLTTKATTTRATSSTSTPSSTPGTT 4862
Query: 1522 SGAME-TTRVTVIFAGSPNITVSSRSPPAPRF---PLMTKAVTVRGHGSLPVRTTPP--- 1574
E TT T A P T S S P + L T A T GS ++ P
Sbjct: 4863 WILTELTTAATTTAATGPTATPS--STPGTTWILTELTTTATTTASTGSTATPSSTPGTT 4920
Query: 1575 ----QPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSAS 1630
+PS TA+ + P S S + ++G+ T V S P + + +
Sbjct: 4921 WILTEPSTTATVTV-PTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGTATA 4979
Query: 1631 SP---STPLTVAGTAAEQVPVSPLATRSLEI-VLSTEKGEAGHSQPMGSPASPQPHPLPS 1686
P ST T T+ +P S L T + +T + P +P + + +
Sbjct: 4980 LPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLT 5039
Query: 1687 APPRPAQHTTMATRSPALPPETPAAASL----STATDGLAATPFMSLESTRPSQLLSGLP 1742
A TT AT S A P TP A +T T G ATP S
Sbjct: 5040 A----TATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSS-------------- 5081
Query: 1743 PDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHPPT 1802
P T+L + P TP S I T P+ T S VL T A MT+A T
Sbjct: 5082 PGTAL-------TPPTTTPMSTMSTIHTSSTPETT-----HTSTVLT-TTATMTRATNST 5128
Query: 1803 HIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSM 1862
P LG T + + A TA+ S ST G IL++ ++ T M
Sbjct: 5129 --------ATPSSTLGTTRILTELTTTATTTAATGSTATLSSTPGTTWILTEPSTIATVM 5180
Query: 1863 YGSAEGGPTELTPATSHPLTPLVAEPEGAQ-AGTALPVPTS 1902
+ T T+H TP V TA VP+S
Sbjct: 5181 VPTGSTATASSTLGTAH--TPKVVTTMATMPTATASTVPSS 5219
Score = 84.7 bits (208), Expect = 1e-15
Identities = 95/386 (24%), Positives = 147/386 (38%), Gaps = 60/386 (15%)
Query: 2482 CRQDQILITGRLGDSCCTSYFCACGDCPDSIPE------CQEGEALTVHRNTTELCCPLY 2535
C +DQIL +G C C C PD P+ ++ + + C
Sbjct: 5731 CPEDQILFNAHMG--ICVQA-CPCVG-PDGFPKFPGERWVSNCQSCVCDEGSVSVQCKPL 5786
Query: 2536 QCVCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIP--VPRCHLWEKSQLDEE 2593
C + P + G T + + + CCP C C+ T P +P C ++S +E
Sbjct: 5787 PCDAQGQPPPCNRPGFVT-VTRPRAENPCCPETVCVCNTTTCPQSLPVCPPGQESICTQE 5845
Query: 2594 FMHSVENVCGCAKYECVKAPVCLSR----ELGVMQPGQTVVELSADGVCHTSRCTT--VL 2647
E C C + C + +C +G PG CH C +
Sbjct: 5846 -----EGDC-CPTFRC-RPQLCSYNGTFYGVGATFPGAL--------PCHMCTCLSGDTQ 5890
Query: 2648 DPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTTSLFLPGA 2707
DP + + C Q +E+ R CCG C +CL P+G
Sbjct: 5891 DPTVQCQEDACNNTTCP------QGFEYKRVAGQCCGECVQTACL--TPDGQPVQL--NE 5940
Query: 2708 SW----IADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTCKED 2763
+W + +C + C + +L P SCP ++ GS+ + GCC +C+ED
Sbjct: 5941 TWVNSHVDNCTVYLCEAEGGVHLLTPQPASCPDVSSCR-----GSLRKT--GCCYSCEED 5993
Query: 2764 GRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVGLQR 2823
SC +V I TI ++ T VN+ C+G CP AS Y+ C CC+E +
Sbjct: 5994 --SC-QVRINTTILWHQ-GCETEVNITFCEGSCPGASKYSAEAQAMQHQCTCCQERRVHE 6049
Query: 2824 RSVQLFCATNATWVPYTVQEPTDCAC 2849
+V L C N + + +T C
Sbjct: 6050 ETVPLHC-PNGSAILHTYTHAVQVLC 6074
Score = 83.2 bits (204), Expect = 3e-15
Identities = 133/580 (22%), Positives = 205/580 (35%), Gaps = 65/580 (11%)
Query: 1429 PRTP-THRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTES 1487
P TP T A+ + P TT + +T T S G T T P ++ P +
Sbjct: 4702 PSTPATSSTAMPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTAPPPKVLTSPATT 4761
Query: 1488 PASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGS-PNITVSSRS 1546
P + A+ + P T +++LPV T T + T+ G+ P T + +
Sbjct: 4762 PTATSSKATSSSSPRT--ATTLPVLTSTATKSTATSVTPIPSSTLGTTGTLPEQTTTPVA 4819
Query: 1547 PPAPRFPLMTKAVTVRGHGSLPVRTTPPQPSLTASPSSRP----------VASPGAISRS 1596
+ P T T TT S T++PSS P A+ +
Sbjct: 4820 TMSTIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATG 4879
Query: 1597 PTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSL 1656
PT++ S TP T +++ T A S S +TP + GT + P T ++
Sbjct: 4880 PTATPSS----TPGTTWILTELTTTATTTA-STGSTATPSSTPGTT--WILTEPSTTATV 4932
Query: 1657 EIVLSTEKGEAGHSQPMGSPASPQPHPLP---SAPPRPAQHTTMATRSPAL--PPETPAA 1711
+ + + G+P P S+ P+ AT PAL TP A
Sbjct: 4933 TVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTA 4992
Query: 1712 ASLSTATDGLAATPFMSL-ESTRPSQLLSGLPPDTSLPLAKVGT--SAPVATPGPKASVI 1768
S + T + L ++T P+ +S P ++ T +A T G SV
Sbjct: 4993 TSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTATATTTGATGSVA 5052
Query: 1769 T---TPLQPQATTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAA---GTAPGLLLGATLP 1822
T TP T +P T + FT A + P T + PP T + +T
Sbjct: 5053 TPSSTPGTAHTTKVPTTTTTG---FT--ATPSSSPGTALTPPTTTPMSTMSTIHTSSTPE 5107
Query: 1823 TSGVLPVAEGTASMV----SVVPRKSTTGKVAILSKQVSLPTSMYGSAEGGPTELTPATS 1878
T+ V TA+M S ST G IL++ + T+ + TP T+
Sbjct: 5108 TTHTSTVLTTTATMTRATNSTATPSSTLGTTRILTELTTTATTTAATGSTATLSSTPGTT 5167
Query: 1879 HPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLAEAHGTSAGPHLA 1938
LT EP S ++ P S L AH +A
Sbjct: 5168 WILT----EP-----------------STIATVMVPTGSTATASSTLGTAHTPKVVTTMA 5206
Query: 1939 AEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTT 1978
P A+T PS + L +L T + + S++
Sbjct: 5207 TMPTATASTVPSSSTVGTTRTPAVLPSSLPTFSVSTVSSS 5246
Score = 80.9 bits (198), Expect = 2e-14
Identities = 136/523 (26%), Positives = 192/523 (36%), Gaps = 84/523 (16%)
Query: 1501 PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGS-------------PNITVSSRSP 1547
P TP +SS + TP + + TT T GS P + S +
Sbjct: 4702 PSTPATSSTAMPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTAPPPKVLTSPATT 4761
Query: 1548 PAPRFPLMTKAVTVRGHGSLPVRTT----PPQPSLTASPSS-------------RPVASP 1590
P T + + R +LPV T+ S+T PSS PVA+
Sbjct: 4762 PTATSSKATSSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGTLPEQTTTPVATM 4821
Query: 1591 GAISRSPTSSGSH-KAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAG--TAAEQVP 1647
I S T +H VLT T + + P+ + T LT A TAA
Sbjct: 4822 STIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATGPT 4881
Query: 1648 VSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPRPAQHTTMATRSPALPPE 1707
+P +T +L+ A + GS A+P P + +T AT +P
Sbjct: 4882 ATPSSTPGTTWILTELTTTATTTASTGSTATPS--STPGTTWILTEPSTTAT--VTVPTG 4937
Query: 1708 TPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPD------TSLPLAKVGTSAPVATP 1761
+ A AS + AT A TP +S +T P+ S P T+LP + + P AT
Sbjct: 4938 STATASSTQAT---AGTPHVSTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATS 4994
Query: 1762 G---PKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLG 1818
P +S+ TT + TT P T+S P + T T A T G
Sbjct: 4995 FTAIPSSSLGTTWTRLSQTTTPTATMSTATP----SSTPETVHTSTVLTATATTTGATGS 5050
Query: 1819 ATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGSAEGGPTELTPATS 1878
P+S GTA + VP +TTG A P+S G+A PT TP ++
Sbjct: 5051 VATPSS-----TPGTAH-TTKVPTTTTTGFTA-------TPSSSPGTALTPPT-TTPMST 5096
Query: 1879 HPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLAEAHGTSAGPHLA 1938
+ PE T L T+ ++R + TA S L GT+ +
Sbjct: 5097 MSTIHTSSTPETTHTSTVL--TTTATMTRATNSTATPSSTL----------GTT---RIL 5141
Query: 1939 AEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 1981
E ATT + S LS G L T + +T VP
Sbjct: 5142 TELTTTATTTAATGSTATLSSTPGTTWIL--TEPSTIATVMVP 5182
Score = 79.3 bits (194), Expect = 5e-14
Identities = 69/285 (24%), Positives = 110/285 (38%), Gaps = 18/285 (6%)
Query: 2107 VTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASK 2166
V I V V+ PV P S+ G I+ + + + + W H L++ +K
Sbjct: 143 VVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKVEARLGLVLMWNHDDSLLLELDTK 202
Query: 2167 TSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDS 2226
+ + GLCG +G L + + P F + ++ P
Sbjct: 203 YAN-KTCGLCGDFNGMPVVSELLSHNTKL----TPMEFGNLQKMDDPTEQCQDPVPEPPR 257
Query: 2227 CATTDCSPCLRMVSNRTFSACHRFVPPESFCEL------WIRDTKYVQQPCVALTVYVAM 2280
+T C ++ + FS C V S+ E + DT + C L Y
Sbjct: 258 NCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLLSCVCHTLAEYSRQ 317
Query: 2281 C-HKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGC 2339
C H + +WR D+CP C ++ Y C + C TC + +HC GC
Sbjct: 318 CTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCAD--TCSNQEHSRACEDHCVA---GC 372
Query: 2340 VCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGC 2384
C EGT+L C+P +KCAC + G A G T+++ + C
Sbjct: 373 FCPEGTVLDDIGQTGCVPVSKCACVYN-GAAYAPGATYSTDCTNC 416
Score = 79.0 bits (193), Expect = 6e-14
Identities = 71/280 (25%), Positives = 120/280 (42%), Gaps = 44/280 (15%)
Query: 913 CTAYGDRHYRTFDGLPFDFVGACKV-------------HLVKSTSDVSFSVIVENVNCYS 959
C+ +G HY+TFDG F F G C ++ S S + + V
Sbjct: 81 CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQESAAPTLSRVLMKV 140
Query: 960 SGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLL 1019
G++ I + G+ L+ +G+P F + V + +T V + + L+
Sbjct: 141 DGVV----IQLTKGSVLV-----NGHPVLLPF--SQSGVLIQQSSSYTKVE-ARLGLVLM 188
Query: 1020 WDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDT 1079
W+ ++ ++ ++ + GLCG+F+ + N +LT P EFG+ ++ D
Sbjct: 189 WNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLT-PMEFGN----LQKMD- 242
Query: 1080 LDPRDMCVLNPLREPFAKKECS--------ILLSEVFEICHPVVDVTWFYSNCLTDTCGC 1131
DP + C +P+ EP + CS +L ++F C +VDV + C D C C
Sbjct: 243 -DPTEQCQ-DPVPEP--PRNCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFC 298
Query: 1132 SQGGDCECFCASVSAYAHQCCQ-HGVAVDWRTPRLCPYDC 1170
C C +++ Y+ QC G+ DWR P CP C
Sbjct: 299 EDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKC 338
Score = 75.1 bits (183), Expect = 9e-13
Identities = 115/455 (25%), Positives = 168/455 (36%), Gaps = 80/455 (17%)
Query: 1398 VPTEALGNE-TLPPSQGLP--TPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTA 1454
+P+ LG TLP P T S P + E+ T T LT A T A + T
Sbjct: 3652 IPSFTLGTTGTLPEQTTTPMATMSTIHPSSTPETTHTST---VLTTKATTTRATSSMST- 3707
Query: 1455 TEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQ 1514
P +PG T + T + GPT +P+S T +L P T + ++P
Sbjct: 3708 ---PSSTPGTTWILTELTTAATTTAA-TGPTATPSSTPGTTWILTEPSTTATVTVPTG-S 3762
Query: 1515 TPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRT--- 1571
T T T +V A +P + +SSR+ P+ T +R + P T
Sbjct: 3763 TATASSTRATAGTLKVLTSTATTPTV-ISSRATPSSSPGTATALPALRSTATTPTATSVT 3821
Query: 1572 ------------------TPPQPSLTASPSSRP--VASPGAISRSPTSSGSHKAVLTPAV 1611
TP TA+PSS P V + ++ + T++ + +V TP+
Sbjct: 3822 AIPSSSLGTAWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSS 3881
Query: 1612 TKVISRTG-VPQPTQ----AQSASSPSTPLT----VAGTAAEQV------PVSPLATRSL 1656
T + T VP T A +SSP T LT ++ T P S T
Sbjct: 3882 TPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHT 3941
Query: 1657 EIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPRPAQHTTMATRSPALPPETP--AAASL 1714
VL+T +S Q PP P +TT T +LPP +P +
Sbjct: 3942 ATVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVP--NTTATTHGRSLPPSSPHTVRTAW 3999
Query: 1715 STATDGLAATPFMS-----------------------LESTRPSQLLSGLPPD--TSLPL 1749
++AT G+ T ++ L S PS + PP T+ P
Sbjct: 4000 TSATSGILGTTHITEPSTVTSHTPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPG 4059
Query: 1750 AKVGTSAPVATPGPKASVITTPLQPQATTLPAQTL 1784
GTS AT P + +T L T+ P T+
Sbjct: 4060 HTRGTSRTTATATPSKTRTSTLLPSSPTSAPITTV 4094
Score = 73.9 bits (180), Expect = 2e-12
Identities = 104/444 (23%), Positives = 158/444 (35%), Gaps = 89/444 (20%)
Query: 2019 GLAVRVGGDRCC---PLWECACR-----CSIFPDLSFVTFDGSHVALFKEAIYILSQSPD 2070
G +RV + C WEC+ R C + D F+TFDG + YIL+Q
Sbjct: 1526 GETIRVDCNTCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYC 1585
Query: 2071 EMLTVH-VLDCKSANLGHLNWPPFCLVMLNM---THLAHQVTI------DRFNRKVTVDL 2120
T H + N+ C + + A V+ + R+ +V
Sbjct: 1586 GDNTTHGTFRIVTENIPCGTTGTTCSKAIKLFVEVRTAPAVSTPDPAANEPAPREASVGF 1645
Query: 2121 QPVWPPVSRYGFRIEDTGH-------------------MYMILTPSDIQIQWLHSSGLMI 2161
+ PP+ Y +++ +++++ + + W + + I
Sbjct: 1646 RQRLPPLQSYELILQEGTFKAVARGPGGDPPYKIRYMGIFLVIETHGMAVSWDRKTSVFI 1705
Query: 2162 VEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQV----PSSLTSV 2217
+ K + GLCG D +A ND + SVVG D F +SW++ P +L
Sbjct: 1706 -RLHQDYKGRVCGLCGNFDDNAINDFATRSRSVVG---DALEFGNSWKLSPSCPDALAPK 1761
Query: 2218 GQTRFRP--DSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----- 2270
P S A CS ++ TF+AC V + E + D
Sbjct: 1762 DPCTANPFRKSWAQKQCS----ILHGPTFAACRSQVDSTKYYEACVNDACACDSGGDCEC 1817
Query: 2271 -CVALTVYVAMCHKFHVCIEWRRSDYCPFLC-------SSDSTYQACVTACEPPKTCQDG 2322
C A+ Y CH +C+ WR D CP C + YQ C C KTC++
Sbjct: 1818 FCTAVAAYAQACHDAGLCVSWRTPDTCPLFCDFYNPHGGCEWHYQPCGAPC--LKTCRN- 1874
Query: 2323 ILGPLDPEHCQV---LGEGCV--CSEGTILHRRHSALCIPEAKCACTDSMG--------V 2369
HC V EGC C C+ A+C C D G V
Sbjct: 1875 -----PSGHCLVDLPGLEGCYPKCPPSQPFFNEDQMKCV--AQCGCYDKDGNYYDVGARV 1927
Query: 2370 PRALG-ETWNSSLSGC-CQHQCQA 2391
P A ++ N + SG C H +A
Sbjct: 1928 PTAENCQSCNCTPSGIQCAHSLEA 1951
Score = 70.9 bits (172), Expect = 2e-11
Identities = 137/593 (23%), Positives = 211/593 (35%), Gaps = 75/593 (12%)
Query: 1431 TPTHRPALTPAAPLTTALNPPVTATE-EPVVSPGPTQTTLQQPLELTASQLPAGPTESP- 1488
T T R A P TTA P VT+++ P SPG T T L P + + P + +P
Sbjct: 2620 TSTLRTAPPPKVLTTTATTPTVTSSKATPSSSPG-TATAL--PALRSTATTPTATSVTPI 2676
Query: 1489 --ASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRS 1546
+S G T + L+ TP ++ + T TP T+ V A + T S +
Sbjct: 2677 PSSSLGTTWTRLSQTTTPTAT-----MSTATPSSTPETAHTSTVLTATATTTGATGSVAT 2731
Query: 1547 PPA-PRFPLMTKAVTVRGHGSLPVRTTPPQPSLT----ASPSSRPVASPGAISRSPTSSG 1601
P + P TK T G ++ P +LT S ++ P ++ S
Sbjct: 2732 PSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGT 2791
Query: 1602 SHKAVLTPAVTKVISRTGVPQPTQAQSAS----SPSTPLTVAGTAAEQVPVSPLATRSLE 1657
+H A + T ++ + P+ + S +P P T+A T +P P + ++
Sbjct: 2792 THTATVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTMATTHGRSLP--PSSPHTVR 2849
Query: 1658 IVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPRPAQHTTMA----------TRSPALPPE 1707
++ + + P++ H L +A QH+T A T SP P
Sbjct: 2850 TAWTSATSGILGTTHITEPSTVTSHTL-AATTGTTQHSTPALSSPHPSSRTTESPPSPGT 2908
Query: 1708 TPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAPVATPGPKASV 1767
T + +T+ ATP TR S LL P TSAP+ T V
Sbjct: 2909 TTPGHTTATSRTTATATP----SKTRTSTLLPSSP-----------TSAPITT------V 2947
Query: 1768 ITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAP-GLLLGAT----LP 1822
+T +PQ S +P + A A P GL A +P
Sbjct: 2948 VTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVP 3007
Query: 1823 TSGVLPVAEGTASMVSVVPRKSTTGKVAI-LSKQVSLPTSMYGSAEGGPT-------ELT 1874
+ V E + V + GK + + ++ + YG P T
Sbjct: 3008 LRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSST 3067
Query: 1875 PATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLAEAHGTSAG 1934
P T+ LT L ++ + P+S T P + V +P + A +S
Sbjct: 3068 PGTTWILTELTTTATTTESTGSTATPSS-TPGTTWILTEPSTTATVTVPTGSTATASSTQ 3126
Query: 1935 PHLAAEPVDEATTEPSGRSAPALSIVE-GLAEAL-----ATTTEANTSTTCVP 1981
V T P+ S+ A G A AL TT TS T +P
Sbjct: 3127 ATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIP 3179
Score = 69.3 bits (168), Expect = 5e-11
Identities = 105/439 (23%), Positives = 159/439 (36%), Gaps = 58/439 (13%)
Query: 1429 PRTPTHRPALTPAA-PLTTALNPPVTATEEPVVSPGPTQTT---------LQQPLELTAS 1478
P TP TP++ P TT + +T T S G T T L +P
Sbjct: 4200 PSTPATSSTATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEPSTTATV 4259
Query: 1479 QLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSP 1538
+P G T + +S TA PH +++ P + S T P
Sbjct: 4260 TVPTGSTATASSTQATA---GTPHVSTTATTPTVTSSKATPFSSPGTAT--------ALP 4308
Query: 1539 NITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRTTPPQPSLTASPSSRP--VASPGAISRS 1596
+ ++ +P A F + + L TTP TA+PSS P + ++ +
Sbjct: 4309 ALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTT 4368
Query: 1597 PTSSGSHKAVLTPAVTK-VISRTGVPQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRS 1655
T++ + +V TP+ T T VP T +PS+ SP R+
Sbjct: 4369 ATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSS--------------SPGTART 4414
Query: 1656 LEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPRPAQHTTMATRSPALPPETPAAASLS 1715
+ +ST + P S ++ P +P P T + T + + + A S S
Sbjct: 4415 PPVWISTT------TTPTTSGSTVTPSSVPGTTHTP---TVLTTTTTTVATGSMATPSSS 4465
Query: 1716 TATDGLAAT-PFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTPLQP 1774
T T G T P + +T + LS P T TS + T T P
Sbjct: 4466 TQTSGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTP 4525
Query: 1775 QATTLPAQTLSPVL--PFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLP----TSGVLP 1828
ATT Q +P L P + T++ P P TA P TS +LP
Sbjct: 4526 AATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLP 4585
Query: 1829 VAEGTASMVSVVPRKSTTG 1847
+ +A + +VV TTG
Sbjct: 4586 SSPTSAPITTVV----TTG 4600
Score = 68.9 bits (167), Expect = 7e-11
Identities = 157/651 (24%), Positives = 232/651 (35%), Gaps = 124/651 (19%)
Query: 1407 TLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQ 1466
T PP+ L T + Q +P+ PT P LT A PP + T P +S G T
Sbjct: 2302 TPPPTTELETATTTTTQALFSTPQ-PTSSPGLTRA--------PPASTTAVPTLSEGLTS 2352
Query: 1467 TTLQQPLELTAS---QLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSG 1523
L + PAG TE P GV S L P S+LP +G
Sbjct: 2353 PRYTSTLGTATTGGPTTPAGSTE-PTVPGVATSTL-----PTRSALPGT---------TG 2397
Query: 1524 AMETTRVTVIFAGSPNITVSSRSPP------APRFPLMTK-AVTVRGHGSLP-VRTTPPQ 1575
++ T R + +P +SR+ P A + PL T A T+ S T+ P+
Sbjct: 2398 SLGTWRPSQPPTLAPTTMATSRARPTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPR 2457
Query: 1576 PSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVP-------QPTQAQS 1628
T SP + S G P K T +GV + +A
Sbjct: 2458 TETTMSPLTNTTTSQGTTRCQP------KCEWTEWFDVDFPTSGVAGGDMETFENIRAAG 2511
Query: 1629 ASSPSTPLTVAGTAAEQVP------VSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPH 1682
P ++ AE P V + T SLE L+ + + M + +
Sbjct: 2512 GKMCWAPKSIE-CRAENYPEVSIDQVGQVLTCSLETGLTCKNEDQTGRFNMCFNYNVRVL 2570
Query: 1683 PLPSAPPRPAQHTTMATRSPALPPET------PAAASLSTATDGLAATPFMSLESTRPSQ 1736
P+ T +T +P+ P T P + +TA+ G ATP +L + P +
Sbjct: 2571 CCDDYSHCPSTPATSSTATPSSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPK 2630
Query: 1737 LL-----------------SGLPPDTSLPLAKVGTSAPVA---TPGPKASVITTPLQPQA 1776
+L S T+LP + + P A TP P +S+ TT +
Sbjct: 2631 VLTTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQ 2690
Query: 1777 TTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASM 1836
TT P T+S P + AH T + A T G P+S GTA
Sbjct: 2691 TTTPTATMSTATP--SSTPETAHTSTVLT--ATATTTGATGSVATPSS-----TPGTAH- 2740
Query: 1837 VSVVPRKSTTGKVAILSKQ--VSLPTSMYGSAEGGPT--------ELTPATSHPLTPLVA 1886
+ VP +TTG A S +L ++ S PT P T+H T L
Sbjct: 2741 TTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTT 2800
Query: 1887 EPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLAEAHGTS---AGPHLAAEPVD 1943
G ++ P+S + + T P + +A HG S + PH
Sbjct: 2801 TTTTVATG-SMATPSSSTQTSGTTHTPPVPN------TMATTHGRSLPPSSPHTVRTAWT 2853
Query: 1944 EAT---------TEPSGRSAPALSIVEGLAE----ALATTTEANTSTTCVP 1981
AT TEPS ++ L+ G + AL++ ++ +T P
Sbjct: 2854 SATSGILGTTHITEPSTVTSHTLAATTGTTQHSTPALSSPHPSSRTTESPP 2904
Score = 68.9 bits (167), Expect = 7e-11
Identities = 79/314 (25%), Positives = 115/314 (36%), Gaps = 52/314 (16%)
Query: 895 CVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDV--SFSVIV 952
CV RG + P A C+ +G HY TFDG + F G C L++ + S+ +
Sbjct: 5397 CVGGRG-----ITPGAGICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYL 5451
Query: 953 ENVNCYSSGMI------CRKFISINVGN---------------SLIVFDDDSGNPSPESF 991
+N C +S C + +SI+ + LI+FD P S
Sbjct: 5452 DNHYCTASATAAAAAARCPRALSIHYKSMDIVLTVTMVHGKEEGLILFDQ-----IPVSS 5506
Query: 992 LDDKQEVHTWRVGFFTL-VHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNF----- 1045
K V +G T+ V P +++ ++ + + G CG
Sbjct: 5507 GFSKNGVLVSVLGTTTMRVDIPALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQR 5566
Query: 1046 ------DLKTINEMRTPENLELTNPQEFGSSWAAVECPDTLDPRDMCVLNPLREPFAKKE 1099
D T + L WA P T P P P +
Sbjct: 5567 DDCLQRDGTTAASCKDMAKTWLVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQP 5626
Query: 1100 -CSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV 1158
C ++LS+VF CH +V F++ C++D C G E C S+ AYA C GV
Sbjct: 5627 LCDLMLSQVFAECHNLVPPGPFFNACISDHC----RGRLEVPCQSLEAYAELCRARGVCS 5682
Query: 1159 DWR--TPRLCPYDC 1170
DWR T LC C
Sbjct: 5683 DWRGATGGLCDLTC 5696
Score = 67.8 bits (164), Expect = 1e-10
Identities = 84/375 (22%), Positives = 135/375 (36%), Gaps = 36/375 (9%)
Query: 2039 CSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVML 2098
CS + D + TFDG Y+ S+ + + +G V+
Sbjct: 733 CSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCRAAYEDFNVQLRRGLVGSRP------VVT 786
Query: 2099 NMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSG 2158
+ A + ++ N V ++ Q P SR G +E +G + + W +
Sbjct: 787 RVVIKAQGLVLEASNGSVLINGQREELPYSRTGLLVEQSGDYIKVSIRLVLTFLW-NGED 845
Query: 2159 LMIVEASKTSKAQGHGLCGICDG-DAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSV 2217
++E Q GLCG +G A N+ + + P F + ++
Sbjct: 846 SALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLT-----PLQFGNLQKLDGPTEQC 900
Query: 2218 GQTRFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDT-KYVQQPCVALTV 2276
P T + C R + F+ CH V ++ +D + PC
Sbjct: 901 PDPLPLPAGNCTDEEGICHRTLLGPAFAECHALVDSTAYLAACAQDLCRCPTCPCATFVE 960
Query: 2277 YVAMC-HKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVL 2335
Y C H WR + CP C + +Q C + C TC + L +HC
Sbjct: 961 YSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPC--TDTCSNPQRAQLCEDHCV-- 1016
Query: 2336 GEGCVCSEG---TILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGC-CQ---HQ 2388
+GC C G T+L + C+P +C CT G + G ++N++ S C C Q
Sbjct: 1017 -DGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHG-GRTYSPGTSFNTTCSSCTCSGGLWQ 1074
Query: 2389 CQAPDTIVPVDLGCP 2403
CQ DL CP
Sbjct: 1075 CQ--------DLPCP 1081
Score = 67.8 bits (164), Expect = 1e-10
Identities = 114/436 (26%), Positives = 152/436 (34%), Gaps = 95/436 (21%)
Query: 1501 PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVT 1560
P TP +SS TP + TT T GS S+
Sbjct: 2579 PSTPATSSTATPSSTPGTTWILTKPTTTATTTASTGSTATPTST---------------- 2622
Query: 1561 VRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV 1620
+RT PP LT + ++ V S S++ SS A PA+ R+
Sbjct: 2623 --------LRTAPPPKVLTTTATTPTVTS----SKATPSSSPGTATALPAL-----RSTA 2665
Query: 1621 PQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQ 1680
PT PS+ L T Q +P AT S ST E H+ + + +
Sbjct: 2666 TTPTATSVTPIPSSSLGTTWTRLSQT-TTPTATMSTATPSSTP--ETAHTSTVLTATAT- 2721
Query: 1681 PHPLPSAPPRPAQHTTMATRSPALPPETPAAASL----STATDGLAATPFMSLESTRPSQ 1736
TT AT S A P TP A +T T G ATP S+ P
Sbjct: 2722 --------------TTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATP-----SSSPGT 2762
Query: 1737 LLSGLPP----DTSLPLAKVGTSAPVATPGP--KASVITTPLQPQATTLPAQTLSPVLPF 1790
L+ PP T+ P + T P + PG A+V+TT AT A
Sbjct: 2763 ALT--PPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMA--------- 2811
Query: 1791 TPAAMTQAHPPTHI--APPAAGTAPGLLLGATLP----------TSGVLPVAEGT-ASMV 1837
TP++ TQ TH P T G L + P TSG+L T S V
Sbjct: 2812 TPSSSTQTSGTTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTV 2871
Query: 1838 SVVPRKSTTGKVAILSKQVSLPTSMYGSAEGGPTELTPATSHPL----TPLVAEPEGAQA 1893
+ +TTG + +S P + E P+ T H T A P +
Sbjct: 2872 TSHTLAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRT 2931
Query: 1894 GTALP-VPTSYALSRV 1908
T LP PTS ++ V
Sbjct: 2932 STLLPSSPTSAPITTV 2947
Score = 67.0 bits (162), Expect = 3e-10
Identities = 115/507 (22%), Positives = 168/507 (33%), Gaps = 46/507 (9%)
Query: 1501 PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVT 1560
P TP +SS TP + T T GS I S+ P L + A T
Sbjct: 3555 PSTPATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATT 3614
Query: 1561 -------VRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVT- 1612
S TT P + TA+ S+ +P T+ + TP T
Sbjct: 3615 PTATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLPEQTTTPMATM 3674
Query: 1613 KVISRTGVPQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQP 1672
I + P+ T + + T A T++ P S T + L+T + P
Sbjct: 3675 STIHPSSTPETTHTSTVLTTKATTTRA-TSSMSTPSSTPGTTWILTELTTAATTTAATGP 3733
Query: 1673 MGSPASPQPHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLEST 1732
+P+S P T+ T S A T A A A TP +
Sbjct: 3734 TATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTATTPTVISSRA 3793
Query: 1733 RPSQLLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTP 1792
PS S T+LP + + P AT + I + A T +QT +P +
Sbjct: 3794 TPS---SSPGTATALPALRSTATTPTAT---SVTAIPSSSLGTAWTRLSQTTTPTATMST 3847
Query: 1793 AAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAIL 1852
A + H + T ++ T P GTA + VP +TTG A
Sbjct: 3848 ATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTP---GTAH-TTKVPTTTTTGFTA-- 3901
Query: 1853 SKQVSLPTSMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSART 1912
P+S G+A P ++ T+ P +++P T A + T
Sbjct: 3902 -----TPSSSPGTALTPPVWISTTTTPTTRGSTVTP------SSIPGTTHTATVLTTTTT 3950
Query: 1913 APQDSMLVLLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALS-------IVEGLAE 1965
+ + GT+ P PV T GRS P S +
Sbjct: 3951 TVATGSMATPSSSTQTSGTTHTP-----PVPNTTATTHGRSLPPSSPHTVRTAWTSATSG 4005
Query: 1966 ALATT--TEANTSTTCVPIAEQDCVRH 1990
L TT TE +T T+ P A +H
Sbjct: 4006 ILGTTHITEPSTVTSHTPAATTSTTQH 4032
Score = 66.2 bits (160), Expect = 4e-10
Identities = 140/612 (22%), Positives = 207/612 (33%), Gaps = 86/612 (14%)
Query: 1397 WVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATE 1456
W+ TE T+ +PT S +Q + TP TTA P VT+++
Sbjct: 4248 WILTEPSTTATVT----VPTGSTATASSTQATAGTPHVS---------TTATTPTVTSSK 4294
Query: 1457 -EPVVSPGPTQTTLQQPLELTASQLPAGPTESPASK-GVTASLLAIPHTPESS-SLPVAL 1513
P SPG T T L + T P+S G T + L+ TP ++ S
Sbjct: 4295 ATPFSSPG-TATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPS 4353
Query: 1514 QTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRT-- 1571
TP S + TT T GS + S P T G P +
Sbjct: 4354 STPETAHTSTVLTTTATTTRATGS---VATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPG 4410
Query: 1572 TPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSAS- 1630
T P + S ++ P S ++ S +H + T ++ + P+ + S
Sbjct: 4411 TARTPPVWISTTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSG 4470
Query: 1631 ---SPSTPLTVAGTAAEQV-PVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPS 1686
+P P T A T + P SP R+ S G G + + P++ H P+
Sbjct: 4471 TTHTPPVPNTTATTHGRSLSPSSPHTVRT--AWTSATSGTLGTTH-ITEPSTGTSH-TPA 4526
Query: 1687 APPRPAQHTTMA----------TRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQ 1736
A QH+T A T SP P T + +T+ ATP TR S
Sbjct: 4527 ATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATP----SKTRTST 4582
Query: 1737 LLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMT 1796
LL P TSAP+ T V+TT +PQ S +P
Sbjct: 4583 LLPSSP-----------TSAPITT------VVTTGCEPQCAWSEWLDYSYPMPGPSGGDF 4625
Query: 1797 QAHPPTHIAPPAAGTAP-GLLLGAT----LPTSGVLPVAEGTASMVSVVPRKSTTGKVAI 1851
+ A A P GL A +P + V E + V + GK +
Sbjct: 4626 DTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLGELGQVVECSLDFGLVCRNREQVGKFKM 4685
Query: 1852 -LSKQVSLPTSMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSA 1910
+ ++ + YG TPATS P + P T L + S S
Sbjct: 4686 CFNYEIRVFCCNYGHCPS-----TPATSSTAMP-SSTPGTTWILTELTTTATTTASTGST 4739
Query: 1911 RTAPQDSMLVLLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATT 1970
T + GT+ P + P T S ++ + L +T
Sbjct: 4740 ATP------------SSTPGTAPPPKVLTSPATTPTATSSKATSSSSPRTATTLPVLTST 4787
Query: 1971 TEANTSTTCVPI 1982
+T+T+ PI
Sbjct: 4788 ATKSTATSVTPI 4799
Score = 65.1 bits (157), Expect = 1e-09
Identities = 144/620 (23%), Positives = 218/620 (35%), Gaps = 102/620 (16%)
Query: 1397 WVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATE 1456
W+ TE T+ +PT S +Q + TP TTA P VT+++
Sbjct: 3101 WILTEPSTTATVT----VPTGSTATASSTQATAGTPHVS---------TTATTPTVTSSK 3147
Query: 1457 -EPVVSPGPTQTTLQQPLELTASQLPAGPTESPASK-GVTASLLAIPHTPESSSLPVALQ 1514
P SPG T T L + T P+S G T + L+ TP ++ +
Sbjct: 3148 ATPFSSPG-TATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTAT-----MS 3201
Query: 1515 TPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPA-PRFPLMTKAVTVRGHGSLPVRTTP 1573
T TP + T+ V A + T S +P + P TK +T G ++
Sbjct: 3202 TATPSSTPETVHTSTVLTTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSS 3261
Query: 1574 PQPSLT----ASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSA 1629
P + T S ++ P ++ S +H + T ++ + P+ +
Sbjct: 3262 PGTARTLPVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQT 3321
Query: 1630 S----SPSTPLTVAGTAAEQV-PVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPL 1684
S +P P T A T + P SP R+ S G G + + P++ H
Sbjct: 3322 SGTTHTPPVPNTTATTHGRSLSPSSPHTVRT--AWTSATSGTLGTTH-ITEPSTGTSH-T 3377
Query: 1685 PSAPPRPAQHTTMA----------TRSPALPPETPAAASLSTATDGLAATPFMSLESTRP 1734
P+A QH+T A T SP P T + +T+ ATP TR
Sbjct: 3378 PAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRATSRTTATATP----SKTRT 3433
Query: 1735 SQLLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAA 1794
S LL P TSAP+ T V+T +PQ S +P
Sbjct: 3434 STLLPSSP-----------TSAPITT------VVTMGCEPQCAWSEWLDYSYPMPGPSGG 3476
Query: 1795 MTQAHPPTHIAPPAAGTAP-GLLLGAT----LPTSGVLPVAEGTASMVSVVPRKSTTGKV 1849
+ A A P GL A +P + V E + V + GK
Sbjct: 3477 DFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKF 3536
Query: 1850 AI-LSKQVSLPTSMYGSAEGGPTELTPATSHPLTPLVAE------PEGAQAGTALPVPTS 1902
+ + ++ + YG TPATS TP E A T S
Sbjct: 3537 KMCFNYEIRVFCCNYGHCPS-----TPATSSTATPSSTPGTTWILTEQTTAATTTATTGS 3591
Query: 1903 YALSRVSARTAPQDSMLVLLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEG 1962
A+ + TAP +L T+ P + +AT+ S R+A L +
Sbjct: 3592 TAIPSSTPGTAPPPKVLT---------STATTPTATS---SKATSSSSPRTATTLPV--- 3636
Query: 1963 LAEALATTTEANTSTTCVPI 1982
L +T +T+T+ PI
Sbjct: 3637 ----LTSTATKSTATSFTPI 3652
Score = 64.3 bits (155), Expect = 2e-09
Identities = 76/301 (25%), Positives = 117/301 (38%), Gaps = 20/301 (6%)
Query: 1428 SPRTPTHRPALTPAAPL--TTALNPPVTA-TEEPVVSPGPTQTTLQQPLELTASQLPAGP 1484
S TP+ P A P +TA P T+ T P S G T T L Q TA+ A P
Sbjct: 4966 SKATPSSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATP 5025
Query: 1485 TESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSS 1544
+ +P + T+++L T ++ VA + TPG T T F +P+ + +
Sbjct: 5026 SSTPETVH-TSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGT 5084
Query: 1545 RSPPAPRFPLMTKAVTVRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHK 1604
P P+ T + H S TT LT + + + A +P+S+
Sbjct: 5085 ALTPPTTTPMSTMSTI---HTSSTPETTHTSTVLTTTATMTRATNSTA---TPSSTLGTT 5138
Query: 1605 AVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTAAE-QVPVSPLATRSLEIVLSTE 1663
+LT T + S + LT T A VP AT S +
Sbjct: 5139 RILTELTTTATTTAATGSTATLSSTPGTTWILTEPSTIATVMVPTGSTATASSTL----- 5193
Query: 1664 KGEAGHSQPMGSPASPQPHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAA 1723
G A + + + A+ P +A P+ T TR+PA+ P + S+ST + +
Sbjct: 5194 -GTAHTPKVVTTMATM---PTATASTVPSSSTVGTTRTPAVLPSSLPTFSVSTVSSSVLT 5249
Query: 1724 T 1724
T
Sbjct: 5250 T 5250
Score = 62.8 bits (151), Expect = 5e-09
Identities = 138/642 (21%), Positives = 203/642 (31%), Gaps = 106/642 (16%)
Query: 1428 SPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTES 1487
SP T T PAL A TA + T P S G T L Q TA+ A P+ +
Sbjct: 3798 SPGTATALPALRSTATTPTA----TSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPSST 3853
Query: 1488 PASKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPN-------- 1539
P + T+++L T ++ VA + TPG T T F +P+
Sbjct: 3854 PETVH-TSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALT 3912
Query: 1540 --ITVSSRSPPAPR---------------FPLMTKAVTVRGHGSLPVRT----------T 1572
+ +S+ + P R ++T T GS+ + T
Sbjct: 3913 PPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTTHT 3972
Query: 1573 PPQPSLTASPSSR--PVASPGAISRSPTSSGSHKAVL--------------TPAVTKVIS 1616
PP P+ TA+ R P +SP + + TS+ S +L TPA T +
Sbjct: 3973 PPVPNTTATTHGRSLPPSSPHTVRTAWTSATS--GILGTTHITEPSTVTSHTPAATTSTT 4030
Query: 1617 RTGVP-----QPTQAQSASSPS----TPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEA 1667
+ P P+ + S PS TP GT+ +P TR+ +L + A
Sbjct: 4031 QHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPSKTRT-STLLPSSPTSA 4089
Query: 1668 GHSQPMGSPASPQ---------PHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTAT 1718
+ + + PQ +P+P P T + A L
Sbjct: 4090 PITTVVTTGCEPQCAWSEWLDYSYPMPG--PSGGDFDTYSNIRAAGGAVCEQPLGLECRA 4147
Query: 1719 DGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAPV-----------ATPGPKASV 1767
P L L GL + K P S
Sbjct: 4148 QAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSS 4207
Query: 1768 ITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVL 1827
TP TT L+ T + + A P + T P T+PT
Sbjct: 4208 TATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTA 4267
Query: 1828 PVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGSAEGGPTELTPATSHPLTPLVAE 1887
+ A+ + P STT ++ + P S G+A P + AT+ T A
Sbjct: 4268 TASSTQAT--AGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAI 4325
Query: 1888 PEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLAEAHGTSAGPHLAAEPVDEATT 1947
P + T +R+S T P +M P T H + ATT
Sbjct: 4326 PSSSLGTT---------WTRLSQTTTPTATMSTATPS-----STPETAHTSTVLTTTATT 4371
Query: 1948 EPSGRSAPALSIVEGLAEALATTTEANTSTTCVPIAEQDCVR 1989
+ S S G A T T T P + R
Sbjct: 4372 TRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTAR 4413
Score = 61.2 bits (147), Expect = 1e-08
Identities = 63/260 (24%), Positives = 104/260 (40%), Gaps = 22/260 (8%)
Query: 2160 MIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQ 2219
+ V + Q GLCG + + A+D T G V A F ++W+ ++ +
Sbjct: 1205 VFVRLDPAHQGQMCGLCGNFNQNQADDFTALSGVVEATG---AAFANTWKAQAACANARN 1261
Query: 2220 TRFRPDSCATTDCSP----CLRMVS-NRTFSACHRFVPPESFCELWIRDTKYVQQP---- 2270
+ P S + + + C R+ N FS CH + P+ F + DT ++
Sbjct: 1262 SFEDPCSLSVENENYARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNCERSEDCL 1321
Query: 2271 CVALTVYVAMCHKFHVCI-EWRRSDYCPFL--CSSDSTYQACVTACEPPKTCQDGILGPL 2327
C AL+ YV C V + +WR ++ C Y V AC+P TC+ +
Sbjct: 1322 CAALSSYVHACAAKGVQLSDWRDGVCTKYMQNCPKSQRYAYVVDACQP--TCRGLSEADV 1379
Query: 2328 DPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWN--SSLSGCC 2385
V +GC C GT L+ + C+P +C C + G A GE + ++ C
Sbjct: 1380 TCSVSFVPVDGCTCPAGTFLN--DAGACVPAQECPCY-AHGTVLAPGEVVHDEGAVCSCT 1436
Query: 2386 QHQCQAPDTIVPVDLGCPSP 2405
+ + GC +P
Sbjct: 1437 GGKLSCLGASLQKSTGCAAP 1456
Score = 59.7 bits (143), Expect = 4e-08
Identities = 82/355 (23%), Positives = 119/355 (33%), Gaps = 53/355 (14%)
Query: 1336 CEWRYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCPTPQ-VLDEVTQRCVYLEDCVEP 1394
CEW Y C +PC +TCR+P D+P +EGC P CP Q +E +CV C +
Sbjct: 1857 CEWHYQPCGAPCLKTCRNPSGHCLVDLPGLEGCYPKCPPSQPFFNEDQMKCVAQCGCYDK 1916
Query: 1395 -------AVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTP-----AA 1442
VPT G+ E RT +++ + A
Sbjct: 1917 DGNYYDVGARVPTAENCQSCNCTPSGIQCAHSLEACTCTYEDRTYSYQDVIYNTTDGLGA 1976
Query: 1443 PLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPH 1502
L T + V PG TT P T + +P S S + S + +
Sbjct: 1977 CLIAICGSNGTIIRKAVACPGTPATT---PFTFTTAWVP----HSTTSPALPVSTVCVRE 2029
Query: 1503 TPESSSLPVALQTPTPGMVSGAMET--------TRVTVIFAGSPNITVSSRSPPAPRFPL 1554
SS P PG+ G ET +V + A + R+ P PL
Sbjct: 2030 VCRWSSWYNG-HRPEPGLGGGDFETFENLRQRGYQVCPVLA-----DIECRAAQLPDMPL 2083
Query: 1555 --MTKAVTVRGHGSLPVRTTPPQPSLTASPSSR----------PVASPGAISRSPTSSGS 1602
+ + V L + P L R P +PG + S+ +
Sbjct: 2084 EELGQQVDCDRMRGLMCANSQQSPPLCHDYELRVLCCEYVPCGPSPAPGTSPQPSLSAST 2143
Query: 1603 HKAVLTPAVTKVISRTGVPQPTQAQSAS-------SPSTPLTVAGTAAEQVPVSP 1650
AV TP T +T + +S + S S P+TV +A P
Sbjct: 2144 EPAVPTPTQTTATEKTTLWVTPSIRSTAALTSQTGSSSGPVTVTPSAPGTTTCQP 2198
Score = 49.7 bits (117), Expect = 4e-05
Identities = 97/478 (20%), Positives = 160/478 (33%), Gaps = 76/478 (15%)
Query: 1562 RGHGSLPVRTTPPQPSLTASPSS-----RPVASPGAISRSPTSSGSHKAVLTPAVTKVIS 1616
RG + P TT + + T + + +P +SPG ++R+P +S + L+ +T
Sbjct: 2297 RGRATTPPPTTELETATTTTTQALFSTPQPTSSPG-LTRAPPASTTAVPTLSEGLTS--- 2352
Query: 1617 RTGVPQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSP 1676
P+ T ++ P T AG+ VP +T L G G +P P
Sbjct: 2353 ----PRYTSTLGTATTGGPTTPAGSTEPTVPGVATSTLPTRSALPGTTGSLGTWRP-SQP 2407
Query: 1677 ASPQPHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATDGLAATP-----FMSLES 1731
+ P + ++ RP + A++ P P S + + +TP L +
Sbjct: 2408 PTLAPTTMATSRARPTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPRTETTMSPLTN 2467
Query: 1732 TRPSQLLSGLPP--------DTSLPLAKVG-----TSAPVATPGPKASVITTPLQPQATT 1778
T SQ + P D P + V T + G K ++ +A
Sbjct: 2468 TTTSQGTTRCQPKCEWTEWFDVDFPTSGVAGGDMETFENIRAAGGKMCWAPKSIECRAEN 2527
Query: 1779 LPAQTLSPVLPFTPAAM-----------------------------TQAHPPTHIAPPAA 1809
P ++ V ++ +H P+ A +
Sbjct: 2528 YPEVSIDQVGQVLTCSLETGLTCKNEDQTGRFNMCFNYNVRVLCCDDYSHCPSTPATSST 2587
Query: 1810 GT---APGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGSA 1866
T PG T PT+ A T S + T +L+ + PT S+
Sbjct: 2588 ATPSSTPGTTWILTKPTTTATTTA-STGSTATPTSTLRTAPPPKVLTTTATTPT--VTSS 2644
Query: 1867 EGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTS---YALSRVSARTAPQDSMLVLLP 1923
+ P+ +P T+ L L + A + P+P+S +R+S T P +M P
Sbjct: 2645 KATPSS-SPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATP 2703
Query: 1924 QLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 1981
T H + ATT + S S G A T T T P
Sbjct: 2704 S-----STPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATP 2756
Score = 35.4 bits (80), Expect = 0.81
Identities = 20/57 (35%), Positives = 30/57 (52%), Gaps = 6/57 (10%)
Query: 1339 RYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCPTPQ---VLDEVTQR-CVYLEDC 1391
++ C SPC TC +P+ A + V+GC CP + VLD++T C+ L C
Sbjct: 990 QHQECGSPCTDTCSNPQRAQLCEDHCVDGC--FCPPGRSCTVLDDITHSGCLPLGQC 1044
Score = 34.7 bits (78), Expect = 1.4
Identities = 19/54 (35%), Positives = 26/54 (48%), Gaps = 3/54 (5%)
Query: 1339 RYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCPTPQVLDEVTQR-CVYLEDC 1391
+Y C SPC TC + + + V GC CP VLD++ Q CV + C
Sbjct: 343 QYHECRSPCADTCSNQEHSRACEDHCVAGC--FCPEGTVLDDIGQTGCVPVSKC 394
Score = 34.3 bits (77), Expect = 1.8
Identities = 50/245 (20%), Positives = 93/245 (37%), Gaps = 25/245 (10%)
Query: 1977 TTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECA 2036
T CVP+++ CV N + + P C + GG C C
Sbjct: 386 TGCVPVSKCACV-----------YNGAAYAPGATYSTDCTNCTCS---GGRWSCQEVPCP 431
Query: 2037 CRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLV 2096
CS+ F TFDG + + Y+L++ D + + + L CL
Sbjct: 432 GTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCGLTD---SETCLK 488
Query: 2097 MLNMT-HLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPS---DIQIQ 2152
+ ++ A V + + + +V ++ P+S I ++I S + +Q
Sbjct: 489 SVTLSLDGAQTVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQ 548
Query: 2153 WLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPS 2212
+ + L + A K + Q GLCG + A+D G V A A F ++++ +
Sbjct: 549 LVPTMQLFMQLAPKL-RGQTCGLCGNFNSIQADDFRTLSGVVEATA---AAFFNTFKTQA 604
Query: 2213 SLTSV 2217
+ ++
Sbjct: 605 ACPNI 609
>gi|134031945 SCO-spondin [Homo sapiens]
Length = 5147
Score = 546 bits (1408), Expect = e-155
Identities = 350/1132 (30%), Positives = 520/1132 (45%), Gaps = 89/1132 (7%)
Query: 79 CRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVS 138
C +W H TFDG +Y+ G+ +Y L G + ++++ + +C P C R
Sbjct: 195 CASWSGFHYRTFDGRHYHFLGRCTYLLAGAAD---STWAVHLTPGDRC-PQPGHCQRVT- 249
Query: 139 LFFVGEQEIHL-AKEVTHGGMRVQLPH--VMGSARLQQLAGYVIVRHQSAFTLAWDGASA 195
+G +E+ + A V+ G V ++ LQ L ++++ + D +
Sbjct: 250 ---MGPEEVLIQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDRTGS 306
Query: 196 VYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTS 255
+ I + EL G T GLCG N P+DD + G L F +SW+ P G +
Sbjct: 307 ISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWR--LPGSESGCLDA 364
Query: 256 SLPRPPC-------LQQNPGTMQG-VYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQ 307
C PG ++ + C LL PF CHA VSP + +C C
Sbjct: 365 VEVAQGCDPLGLIDADVEPGHLRAEAQDVCHQLLEGPFGQCHAQVSPAEYHEACLFAYCA 424
Query: 308 SM-------GDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 360
G C A Y +ACA+ ++ WR C C Y++C++
Sbjct: 425 GAMAGSGQEGRQQAVCATFASYVQACARRHIHIR-WRKP-GFCERLCPGGQL-YSDCVSL 481
Query: 361 CPASCHP-----RASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSV 415
CP SC SC + CV GC CP GL + CV A CPC + Y PG
Sbjct: 482 CPPSCEAVGQGEEESCREE---CVSGCECPRGLFWNGTLCVPAAHCPCYYCRQRYVPGDT 538
Query: 416 VKEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTF--PATCQYILAKSRSS 473
V++ CN C C G+W C+ A+CPAEC+V GD H+ TFDGR Y+F C+Y L +
Sbjct: 539 VRQLCNPCVCRDGRWHCAQALCPAECAVGGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVK 598
Query: 474 GTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDA 533
G + L++ C G+C+ ++SV L + L +G VL+ Q +P +
Sbjct: 599 GQLLILLEHGAC---DAGSCLHAISVSLED---THIQLRDSGAVLVNGQDVGLPWIGAEG 652
Query: 534 FEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSP 593
+RR SS FL +R G +VL+ Y+ +D R GLCGTF N QDDFL+P
Sbjct: 653 LSVRRASSAFLLLRW-PGAQVLWGLSDPVAYITLDPRHAHQVQGLCGTFTQNQQDDFLTP 711
Query: 594 VGVPESTPQLFGNSWKTL-SACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCS 652
G E++ F + ++ P + L PC H Q +++ AC++L +F C
Sbjct: 712 AGDVETSIAAFASKFQVAGKGRCPSEDSALLSPCTTHSQRHAFAEAACAILHSSVFQECH 771
Query: 653 AFLSPVPYFEQCRRDACRC--GQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEAS 710
+ P++ +C C C G CLC L+ YA C + G +R + C + C
Sbjct: 772 RLVDKEPFYLRCLAAVCGCDPGSDCLCPVLSAYARRCAQEGASPPWRNQ-TLCPVMCPGG 830
Query: 711 KEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQ 770
+EY C CG+ C PE CG G CV GC CP D + CVP +
Sbjct: 831 QEYRECAPACGQHC---GKPEDCGELG-------SCVAGCNCPLGLLWDPEGQ-CVPPSL 879
Query: 771 CSCHFQGVDYPPGDSDIPSLGHCHCKD-GVMSCDSR-APAAA-CPAGQVFVNCSDLHTDL 827
C C Y PG + + C C++ G+ +C +R P+ A CP V+ + L
Sbjct: 880 CPCQLGARRYAPGSATMKECNRCICQERGLWNCTARHCPSQAFCPRELVYAPGACL---- 935
Query: 828 ELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQ 887
TC+ N S A GC CP G + + C P+ CPC G+ Y P
Sbjct: 936 -----LTCDSPSANHSCPAGS--TDGCVCPPGTVLLDERCVPPDLCPCRHSGQWYLPNAT 988
Query: 888 VMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVS 947
+ C+ CVC+ + CT + C A G HY TFDGL F + GAC+ LV+ S +
Sbjct: 989 IQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREASGL- 1047
Query: 948 FSVIVENVNCYSSGMICRKFISINVGNSLI-------VFDDDSGNPSPESFLDDKQEVHT 1000
F+V +N+ C +SG+ C K +++ + +++ V + P+ + +
Sbjct: 1048 FTVSAQNLPCGASGLTCTKALAVRLEGTVVHMLRGRAVTVNGVSVTPPKVYTGPGLSLR- 1106
Query: 1001 WRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLE 1060
R G F L+ +TLLWD T V VQ PQ++G++AGLCG+FD N++R+ + +
Sbjct: 1107 -RAGLFLLLS-THLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVL 1164
Query: 1061 LTNPQEFGSSW-AAVECPDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTW 1119
+ SW + CP+ D C +N R +A+ C LL +F +CH V
Sbjct: 1165 EPTAELAAHSWRLSPLCPEPGDLPHPCTMNTHRAGWARARCGALLQPLFTLCHAEVPPQQ 1224
Query: 1120 FYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCD 1171
Y CL D CGC GGDCEC C++++ YA +C +HG V WR+ LC C+
Sbjct: 1225 HYEWCLYDACGCDSGGDCECLCSAIATYADECARHGHHVRWRSQELCSLQCE 1276
Score = 255 bits (651), Expect = 5e-67
Identities = 153/473 (32%), Positives = 223/473 (47%), Gaps = 29/473 (6%)
Query: 340 LRQCTV-HCKEKAFTYNECI---ACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGC 395
L CT HC +AF E + C +C ++ DGC CP G + D C
Sbjct: 909 LWNCTARHCPSQAFCPRELVYAPGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLLDERC 968
Query: 396 VAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGR 455
V P CPC G Y P + ++EDCN C C +W C+ C +G H+ TFDG
Sbjct: 969 VPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGL 1028
Query: 456 RYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAG 515
+T+P C+Y+L + +SG FTV+ QN PCG + C ++++V L V G
Sbjct: 1029 AFTYPGACEYLLVRE-ASGLFTVSAQNLPCGAS-GLTCTKALAVRLEGT----VVHMLRG 1082
Query: 516 DVLLFDQYKIIPP--YTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVE 573
+ + + PP YT +RR + +FL + T++G+ +L+D G R+ +Q+ ++
Sbjct: 1083 RAVTVNGVSVTPPKVYTGPGLSLRR-AGLFLLLSTHLGLTLLWDG-GTRVLVQLSPQFRG 1140
Query: 574 DTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAA 633
GLCG F+G+ +D S GV E T +L +SW+ C G PC ++ A
Sbjct: 1141 RVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLSPLCPE--PGDLPHPCTMNTHRA 1198
Query: 634 SYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQ----PCLCATLAHYAHLCRR 689
++ C L +F C A + P ++E C DAC C CLC+ +A YA C R
Sbjct: 1199 GWARARCGALLQPLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADECAR 1258
Query: 690 HGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEG 749
HG V +R++ C+L CE + Y C C TC + PE G CVEG
Sbjct: 1259 HGHHVRWRSQ-ELCSLQCEGGQVYEACGPTCPPTCHE-QHPEP-----GWHCQVVACVEG 1311
Query: 750 CACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSC 802
C CP T L A C+ C C + +PPG G+C C++G C
Sbjct: 1312 CFCPEGTLLHGGA--CLEPASCPCEWGRNSFPPGSVLQKDCGNCTCQEGQWHC 1362
Score = 214 bits (546), Expect = 7e-55
Identities = 139/410 (33%), Positives = 195/410 (47%), Gaps = 23/410 (5%)
Query: 32 KCAPSYLFSCFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFD 91
+C P L C + G+ P N R + + G R C+A G H TFD
Sbjct: 967 RCVPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFD 1026
Query: 92 GLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHL-- 149
GL + G Y LV E G F++ N P CG+S TC++A+++ G +H+
Sbjct: 1027 GLAFTYPGACEYLLV--REASGL-FTVSAQNLP-CGASGLTCTKALAVRLEGTV-VHMLR 1081
Query: 150 AKEVTHGGMRVQLPHVMGSARLQ-QLAG-YVIVRHQSAFTLAWDGASAVYIKMSPELLGW 207
+ VT G+ V P V L + AG ++++ TL WDG + V +++SP+ G
Sbjct: 1082 GRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGR 1141
Query: 208 THGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNP 267
GLCG+ + D +DL + G L HSW+ P P LP P + N
Sbjct: 1142 VAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLS----PLCPEPGDLPHPCTM--NT 1195
Query: 268 GTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLC--QSMGDVATWCRALAEYARA 325
+C ALL+P F CHA V P C D C S GD C A+A YA
Sbjct: 1196 HRAGWARARCGALLQPLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADE 1255
Query: 326 CAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCH---PRASCVDSEIACVDGC 382
CA+ G ++ WR+Q C++ C E Y C CP +CH P +ACV+GC
Sbjct: 1256 CARHGHHVR-WRSQ-ELCSLQC-EGGQVYEACGPTCPPTCHEQHPEPGWHCQVVACVEGC 1312
Query: 383 YCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWEC 432
+CP G + G C+ PA CPCE+ +PPGSV+++DC CTC G+W C
Sbjct: 1313 FCPEGTLLHGGACLEPASCPCEWGRNSFPPGSVLQKDCGNCTCQEGQWHC 1362
Score = 146 bits (369), Expect = 3e-34
Identities = 152/516 (29%), Positives = 203/516 (39%), Gaps = 72/516 (13%)
Query: 336 WRTQLRQCT-----VHCKE---KAFTYNECIACCPASCHPRASCVDSEIACVDGCYC-PN 386
W +R C HC E KA C A C +A ++ ++ C P
Sbjct: 87 WNRTVRTCCPGWGGAHCTEALAKASPEGHCFAMW--QCQLQAGSANASAGSLEECCARPW 144
Query: 387 GLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDC-NTCTCTSGKWECSTAVCPAECSVTG 445
G + DG A C + + PGS G+ A C+
Sbjct: 145 GQSWWDGSSQACRSC-----SSRHLPGSASSPALLQPLAGAVGQLWSQHQRPSATCASWS 199
Query: 446 DIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDP 505
H+ TFDGR Y F C Y+LA + S T+ V L Q G C Q V++
Sbjct: 200 GFHYRTFDGRHYHFLGRCTYLLAGAADS-TWAVHLTPGD-RCPQPGHC-QRVTM------ 250
Query: 506 RRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS----SVFLRVRTNVGVRVLYDREGL 561
+ L QAG+V + Q ++P ++ + LS +L + +GV V DR G
Sbjct: 251 GPEEVLIQAGNVSVKGQ--LVP--EGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDRTG- 305
Query: 562 RLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWK-------TLSAC 614
+ + VD T GLCG +NG +DDF+ P G FGNSW+ L A
Sbjct: 306 SISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSESGCLDAV 365
Query: 615 SPLVSGSPLDPCDV-----HLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDAC 669
PL D HL+A + V C L F C A +SP Y E C C
Sbjct: 366 EVAQGCDPLGLIDADVEPGHLRAEAQDV--CHQLLEGPFGQCHAQVSPAEYHEACLFAYC 423
Query: 670 RCG---------QPCLCATLAHYAHLC-RRHGLPVDFRARLPA-CALSCEASKEYSPCVA 718
Q +CAT A Y C RRH + R R P C C + YS CV+
Sbjct: 424 AGAMAGSGQEGRQQAVCATFASYVQACARRH---IHIRWRKPGFCERLCPGGQLYSDCVS 480
Query: 719 PCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGV 778
C +C EA G G ++ R+ECV GC CP + + LCVP C C++
Sbjct: 481 LCPPSC------EAVG-QGEEESCREECVSGCECPRGLFWN--GTLCVPAAHCPCYYCRQ 531
Query: 779 DYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAG 814
Y PGD+ C C+DG C A C G
Sbjct: 532 RYVPGDTVRQLCNPCVCRDGRWHCAQALCPAECAVG 567
Score = 98.2 bits (243), Expect = 1e-19
Identities = 133/533 (24%), Positives = 184/533 (34%), Gaps = 114/533 (21%)
Query: 2033 WEC-----ACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGH 2087
W C + RC +VTFDG Y+L + + TV + G
Sbjct: 1003 WHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREASGLFTVSAQNLPCGASG- 1061
Query: 2088 LNWPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPP--VSRYGFRIEDTGHMYMILT 2145
L V L T + H + R VTV+ V PP + G + G ++ T
Sbjct: 1062 LTCTKALAVRLEGT-VVHMLR----GRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLST 1116
Query: 2146 PSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFL 2205
+ + W ++V+ S + + GLCG DGDA+NDL + G + AE A
Sbjct: 1117 HLGLTLLW-DGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAA--- 1172
Query: 2206 DSWQVPSSLTSVGQTRFRPDSC---------ATTDCSPCLRMVSNRTFSACHRFVPPESF 2256
SW++ G P C A C L+ + F+ CH VPP+
Sbjct: 1173 HSWRLSPLCPEPGDL---PHPCTMNTHRAGWARARCGALLQPL----FTLCHAEVPPQQH 1225
Query: 2257 CELWIRDTKYVQQP------CVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSDSTYQACV 2310
E + D C A+ Y C + + WR + C C Y+AC
Sbjct: 1226 YEWCLYDACGCDSGGDCECLCSAIATYADECARHGHHVRWRSQELCSLQCEGGQVYEACG 1285
Query: 2311 TACEPPKTCQDGILGPLDPEHCQVLG--EGCVCSEGTILHRRHSALCIPEAKCACTDSMG 2368
C P TC + P HCQV+ EGC C EGT+L H C+ A C C
Sbjct: 1286 PTC--PPTCHE--QHPEPGWHCQVVACVEGCFCPEGTLL---HGGACLEPASCPC----- 1333
Query: 2369 VPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCL 2428
W P +++ D G +C C
Sbjct: 1334 -------EWG--------RNSFPPGSVLQKDCG-------NC--------------TCQE 1357
Query: 2429 GT-VCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCECD-PDLC------EAELVP 2480
G C + CE L P C G L QE+ C + CD D C E P
Sbjct: 1358 GQWHCGGDGGHCEELVPACAEGEALC---QENGHCVPHGWLCDNQDDCGDGSDEEGCAAP 1414
Query: 2481 SCRQDQILITGRLGDSCCTSYFC----ACGD--------CPDSIPECQEGEAL 2521
C + Q +T G + C CGD CP + C +G L
Sbjct: 1415 GCGEGQ--MTCSSGHCLPLALLCDRQDDCGDGTDEPSYPCPQGLLACADGRCL 1465
Score = 85.1 bits (209), Expect = 9e-16
Identities = 43/133 (32%), Positives = 59/133 (44%), Gaps = 10/133 (7%)
Query: 316 CRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC------CPASCHPRA 369
C +LA C + TQ CT C E + C CP C +
Sbjct: 2857 CSSLAPGDTTCPGPHSQTRDCNTQ--PCTAQCPENML-FRSAEQCHQEGGPCPRLCLTQG 2913
Query: 370 SCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKED-CNTCTCTSG 428
++ C GC CP GL + C+ ++CPC+ HG LY G++ + D CN CTC SG
Sbjct: 2914 PGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYASGAMARLDSCNNCTCVSG 2973
Query: 429 KWECSTAVCPAEC 441
K C++ CP C
Sbjct: 2974 KMACTSERCPVAC 2986
Score = 81.6 bits (200), Expect = 1e-14
Identities = 96/400 (24%), Positives = 144/400 (36%), Gaps = 59/400 (14%)
Query: 1996 QLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACR----CSIFPDLSFVTFD 2051
Q R S+H P A+ P + LA VG LW R C+ + + TFD
Sbjct: 154 QACRSCSSRHLPGSASSPAL-LQPLAGAVG-----QLWSQHQRPSATCASWSGFHYRTFD 207
Query: 2052 GSHVALFKEAIYILSQSPDEMLTVHVLDC-KSANLGHLNWPPFCLVMLNMTHLAHQVTID 2110
G H Y+L+ + D VH+ + GH +T +V I
Sbjct: 208 GRHYHFLGRCTYLLAGAADSTWAVHLTPGDRCPQPGHCQ---------RVTMGPEEVLIQ 258
Query: 2111 RFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKA 2170
N V L P +G ++ G +++L+ + L +G + +
Sbjct: 259 AGNVSVKGQLVPEGQSWLLHGLSLQWLGD-WLVLSGGLGVVVRLDRTGSISISVDHELWG 317
Query: 2171 QGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSC--- 2227
Q GLCG+ +G +D G G A A F +SW++P S + C
Sbjct: 318 QTQGLCGLYNGWPEDDFMEPGG---GLAMLAATFGNSWRLPGSESGCLDAVEVAQGCDPL 374
Query: 2228 --ATTDCSP----------CLRMVSNRTFSACHRFVPPESFCELWI-----------RDT 2264
D P C +++ F CH V P + E +
Sbjct: 375 GLIDADVEPGHLRAEAQDVCHQLLEG-PFGQCHAQVSPAEYHEACLFAYCAGAMAGSGQE 433
Query: 2265 KYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGIL 2324
Q C YV C + H+ I WR+ +C LC Y CV+ C P +C+ +
Sbjct: 434 GRQQAVCATFASYVQACARRHIHIRWRKPGFCERLCPGGQLYSDCVSLC--PPSCE--AV 489
Query: 2325 GPLDPEHC-QVLGEGCVCSEGTILHRRHSALCIPEAKCAC 2363
G + E C + GC C G + LC+P A C C
Sbjct: 490 GQGEEESCREECVSGCECPRGLFW---NGTLCVPAAHCPC 526
Score = 73.9 bits (180), Expect = 2e-12
Identities = 42/129 (32%), Positives = 60/129 (46%), Gaps = 14/129 (10%)
Query: 323 ARACAQ-----AGRPLQGWRTQLRQCT-VHCKEKAFTYNECIAC---CPASCHPRAS--- 370
+R+C+ G P G R Q R C + C+ E + C CP C
Sbjct: 4028 SRSCSSPPSKNGGAPCAGERHQARLCNPMPCEAGCPAGMEVVTCANRCPRRCSDLQEGIV 4087
Query: 371 CVDSEIACVDGCYCPNGLIFEDGGCVAPAECPC-EFHGTLYPPGSVVKEDCNTCTCTSGK 429
C D ++ C GC CP G + +DGGCV C C + G + PGS ++ CN C+C +G+
Sbjct: 4088 CQDDQV-CQKGCRCPKGSLEQDGGCVPIGHCDCTDAQGHSWAPGSQHQDACNNCSCQAGQ 4146
Query: 430 WECSTAVCP 438
C+ CP
Sbjct: 4147 LSCTAQPCP 4155
Score = 72.4 bits (176), Expect = 6e-12
Identities = 97/423 (22%), Positives = 136/423 (32%), Gaps = 146/423 (34%)
Query: 606 NSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCR 665
+ W S C P + S L P A+ +++ + +P L+P+ EQ R
Sbjct: 4526 SEWSEWSPCGPCLPPSALAP------ASRTALEEHWLRDPTGLSPT---LAPLLASEQHR 4576
Query: 666 RDACR--------CGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASK--EYSP 715
C G P LC LC G AC SC+ S +SP
Sbjct: 4577 HRLCLDPATGRPWTGAPHLCTAPLSQQRLCPDPG----------ACPDSCQWSLWGPWSP 4626
Query: 716 CVAPC---------------GRTCQDLASPEACGVDGG---------------------- 738
C PC G C++ + E+C +GG
Sbjct: 4627 CQVPCSGGFRLRWREAEALCGGGCREPWAQESC--NGGPCPECEAQDTVFTLDCANQCPH 4684
Query: 739 ---DDLSRDECVEG-----CACPPDTYLDTQADLCVPRNQCSCHFQGV----DYPPGDSD 786
D R +C++G C CPP + Q CVP + C C + P +
Sbjct: 4685 SCADLWDRVQCLQGPCRPGCRCPPGQLV--QDGRCVPISSCRCGLPSANASWELAPAQAV 4742
Query: 787 IPSLGHCHCKDGVMSCDSRAPAAACPA---GQVFVNCSDLHTDLELSRERTCE------- 836
+C C + + C P CP + +CS + R RTCE
Sbjct: 4743 QLDCQNCTCVNESLVC----PHQECPVLGPWSAWSSCSAPCGGGTMERHRTCEGGPGVAP 4798
Query: 837 --------QQLLNL-----------------------------SVSARGPCLSGCACPQG 859
+Q NL ++ + PC GC CP G
Sbjct: 4799 CQAQDTEQRQECNLQPCPECPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGG 4858
Query: 860 LLRHGDACFLPEECPCT-----W--------KGKEYFPGDQVMSPCHTCVCQRGSFQCTL 906
L H C P CPCT W + +E PG + C CVC G+F C+L
Sbjct: 4859 QLLHNGTCVPPTACPCTQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSL 4918
Query: 907 HPC 909
C
Sbjct: 4919 VDC 4921
Score = 70.9 bits (172), Expect = 2e-11
Identities = 30/78 (38%), Positives = 41/78 (52%), Gaps = 6/78 (7%)
Query: 362 PASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCN 421
PASC ++ + C GC+CP+G++ + CV +CPC G LYPPGS V C
Sbjct: 3103 PASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCAHEGHLYPPGSTVVRPCE 3162
Query: 422 TCTCTSG------KWECS 433
C+C SG W C+
Sbjct: 3163 NCSCVSGLIANCSSWPCA 3180
Score = 70.9 bits (172), Expect = 2e-11
Identities = 54/221 (24%), Positives = 72/221 (32%), Gaps = 28/221 (12%)
Query: 707 CEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCV 766
C + S C C C L C ++ C GC CP L CV
Sbjct: 4818 CPPGQVLSACATSCPCLCWHLQPGAIC--------VQEPCQPGCGCPGGQLLHNGT--CV 4867
Query: 767 PRNQCSC-------------HFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPA 813
P C C Q + PPG + C C G SC P
Sbjct: 4868 PPTACPCTQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCS--LVDCQVPP 4925
Query: 814 GQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEE- 872
G+ + + +L L + E + SGC C G R +PE+
Sbjct: 4926 GETWQQVAP--GELGLCEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDH 4983
Query: 873 CPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPCASTC 913
C C G+ + PG + C +C+C G CT H TC
Sbjct: 4984 CECWHLGRPHLPGSEWQEACESCLCLSGRPVCTQHCSPLTC 5024
Score = 70.1 bits (170), Expect = 3e-11
Identities = 89/374 (23%), Positives = 143/374 (38%), Gaps = 65/374 (17%)
Query: 845 SARGPCLSGCACP-QGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQR---- 899
S G C + C Q + A L E C W G+ ++ G C +C +
Sbjct: 111 SPEGHCFAMWQCQLQAGSANASAGSLEECCARPW-GQSWWDGSS--QACRSCSSRHLPGS 167
Query: 900 GSFQCTLHPCA--------------STCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD 945
S L P A +TC ++ HYRTFDG + F+G C +L+ +D
Sbjct: 168 ASSPALLQPLAGAVGQLWSQHQRPSATCASWSGFHYRTFDGRHYHFLGRC-TYLLAGAAD 226
Query: 946 VSFSV-IVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVG 1004
+++V + C G R + +G ++ +GN S + L E +W +
Sbjct: 227 STWAVHLTPGDRCPQPGHCQR----VTMGPEEVLI--QAGNVSVKGQL--VPEGQSWLLH 278
Query: 1005 FFT-------LVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPE 1057
+ LV + + D+ ++ + + GQ GLCG ++ ++ P
Sbjct: 279 GLSLQWLGDWLVLSGGLGVVVRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPG 338
Query: 1058 NLELTNPQEFGSSWA----------AVECPDTLDPRDMCVLNPLREP-----FAKKECSI 1102
FG+SW AVE DP + +++ EP A+ C
Sbjct: 339 GGLAMLAATFGNSWRLPGSESGCLDAVEVAQGCDP--LGLIDADVEPGHLRAEAQDVCHQ 396
Query: 1103 LLSEVFEICHPVVDVTWFYSNCLTDTC-----GCSQGGDCECFCASVSAYAHQCCQHGVA 1157
LL F CH V ++ CL C G Q G + CA+ ++Y C + +
Sbjct: 397 LLEGPFGQCHAQVSPAEYHEACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIH 456
Query: 1158 VDWRTP----RLCP 1167
+ WR P RLCP
Sbjct: 457 IRWRKPGFCERLCP 470
Score = 70.1 bits (170), Expect = 3e-11
Identities = 65/239 (27%), Positives = 89/239 (37%), Gaps = 50/239 (20%)
Query: 241 WQEQAPNQPP--GPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFT 298
W E P G T S C G E EA + +AC +Y
Sbjct: 3414 WSEWTMCSQPCRGQTRSRSRACACPTPQHGGAPCTGEAGEAGAQHQREACPSY------- 3466
Query: 299 ASCTSDLCQSMGDVATW-----CRALAEYARACA-----QAGRPLQGWRTQLRQC---TV 345
A+C D + G W C + +RAC+ + GRP G TQ R C +
Sbjct: 3467 ATCPVD--GAWGPWGPWSPCDMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENST 3524
Query: 346 HCKE--KAFTYNECIACCPASCH---PRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE 400
C + + + C CP SC P + C + C C CP G + +DG CV PA
Sbjct: 3525 QCTDCGGGQSLHPCGQPCPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAH 3584
Query: 401 CPCEFH--------------GTLY------PPGSVVKEDCNTCTCTSGKWECSTAV-CP 438
C C++ G+ + PG VV C+ CTC +G +C CP
Sbjct: 3585 CRCQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCP 3643
Score = 70.1 bits (170), Expect = 3e-11
Identities = 49/166 (29%), Positives = 61/166 (36%), Gaps = 31/166 (18%)
Query: 301 CTSDLCQSMGDVATWCRALA-------EYARAC--AQAGRPLQGWRTQLRQ-CTVH-CKE 349
C C +G + W A E R C P Q T+ RQ C + C E
Sbjct: 4758 CPHQECPVLGPWSAWSSCSAPCGGGTMERHRTCEGGPGVAPCQAQDTEQRQECNLQPCPE 4817
Query: 350 --KAFTYNECIACCPASC---HPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCE 404
+ C CP C P A CV C GC CP G + +G CV P CPC
Sbjct: 4818 CPPGQVLSACATSCPCLCWHLQPGAICVQEP--CQPGCGCPGGQLLHNGTCVPPTACPCT 4875
Query: 405 FHGTLY-------------PPGSVVKEDCNTCTCTSGKWECSTAVC 437
H + PPG+V+ +C C C G + CS C
Sbjct: 4876 QHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDC 4921
Score = 69.7 bits (169), Expect = 4e-11
Identities = 55/208 (26%), Positives = 73/208 (35%), Gaps = 19/208 (9%)
Query: 716 CVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHF 775
C+AP G S C G D E PP + + L P + CS
Sbjct: 2788 CLAPGGGPGWRSRS-RLCPSPGDSSCPGDATQEEPCSPPVCPVPSIWGLWAPWSTCSAPC 2846
Query: 776 QG---------VDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTD 826
G PGD+ P H +D C+++ A CP +F + H +
Sbjct: 2847 DGGIQTRGRSCSSLAPGDTTCPG-PHSQTRD----CNTQPCTAQCPENMLFRSAEQCHQE 2901
Query: 827 LELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGD 886
R C Q + G C GC CP GL H +C +CPC G+ Y G
Sbjct: 2902 GGPC-PRLCLTQ--GPGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYASGA 2958
Query: 887 QV-MSPCHTCVCQRGSFQCTLHPCASTC 913
+ C+ C C G CT C C
Sbjct: 2959 MARLDSCNNCTCVSGKMACTSERCPVAC 2986
Score = 68.9 bits (167), Expect = 7e-11
Identities = 69/260 (26%), Positives = 85/260 (32%), Gaps = 67/260 (25%)
Query: 700 LPACALSCEASK--EYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTY 757
LP +C A + EYSPC PC R+C DL C GC CPP
Sbjct: 3304 LPCPVTNCTAIEGAEYSPCGPPCPRSCDDLVHCVW------------RCQPGCYCPPGQV 3351
Query: 758 LDTQADLCVPRNQCSC--HFQGVDYPPGD--SDIPSLGHCHCKDGVMSCDS---RAPAAA 810
L + +CV CSC G + PG + HC C +G ++C P
Sbjct: 3352 LSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGRLNCTDLPCPVPGGW 3411
Query: 811 CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLP 870
CP + + CS SR R C PC +G A G +AC
Sbjct: 3412 CPWSE-WTMCSQPCRGQTRSRSRAC---ACPTPQHGGAPC-TGEAGEAGAQHQREACPSY 3466
Query: 871 EECPCTWKGKEYFPGDQVMSPCHTCV------------------------------CQRG 900
CP + P SPC C+ CQ
Sbjct: 3467 ATCPVDGAWGPWGP----WSPCDMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQEN 3522
Query: 901 SFQCT-------LHPCASTC 913
S QCT LHPC C
Sbjct: 3523 STQCTDCGGGQSLHPCGQPC 3542
Score = 68.9 bits (167), Expect = 7e-11
Identities = 56/208 (26%), Positives = 80/208 (38%), Gaps = 31/208 (14%)
Query: 258 PRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATW-- 315
P PC + + C L+ C++ L T C S C ++W
Sbjct: 4315 PWGPCSRSCGPGLASRSGSCPCLMAKADPTCNSTFLHLD-TQGCYSGPCPEECVWSSWSS 4373
Query: 316 -----CRALAEY-------ARACAQAGRPLQGWRTQLRQCTV-HCKEKA----FTYNECI 358
CR L + A A+AG P R C + +C E + F ++ C
Sbjct: 4374 WTRCSCRVLVQQRYRHQGPASRGARAGAPCTRLDGHFRPCLISNCSEDSCTPPFEFHACG 4433
Query: 359 ACCPASCHPRAS---CVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFH------GTL 409
+ C C S C D C GCYCP GL+ + GGC+ P EC C +H G
Sbjct: 4434 SPCAGLCATHLSHQLCQDLP-PCQPGCYCPKGLLEQAGGCIPPEECNC-WHTSAAGAGMT 4491
Query: 410 YPPGSVVKEDCNTCTCTSGKWECSTAVC 437
PG ++ C C C G+ C++ C
Sbjct: 4492 LAPGDRLQLGCKECECRRGELHCTSQGC 4519
Score = 66.6 bits (161), Expect = 3e-10
Identities = 131/556 (23%), Positives = 193/556 (34%), Gaps = 101/556 (18%)
Query: 1957 LSIVEGLAEALATTTEANTSTTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCG 2016
+S+ EA+ E + CV E C R + G L + HCP R
Sbjct: 479 VSLCPPSCEAVGQGEEESCREECVSGCE--CPRGLFWNGTLCV--PAAHCPCYYCRQRY- 533
Query: 2017 ILGLAVRVGGDRCC---PLWECA-----CRCSIFPDLSFVTFDGSHVALF--KEAIYILS 2066
+ G VR + C W CA C++ D ++TFDG + + + Y L
Sbjct: 534 VPGDTVRQLCNPCVCRDGRWHCAQALCPAECAVGGDGHYLTFDGRSYSFWGGQGCRYSLV 593
Query: 2067 QSPDEMLTVHVLDCKSANLGHLNWPPFCL----VMLNMTHLAHQVTIDRFNRKVTVDLQP 2122
Q + + +L+ + + G CL V L TH+ R + V V+ Q
Sbjct: 594 QDYVKGQLLILLEHGACDAGS------CLHAISVSLEDTHIQL-----RDSGAVLVNGQD 642
Query: 2123 VWPP-VSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDG 2181
V P + G + +++L Q+ W S + + Q GLCG
Sbjct: 643 VGLPWIGAEGLSVRRASSAFLLLRWPGAQVLWGLSDPVAYITLDPRHAHQVQGLCGTFTQ 702
Query: 2182 DAANDLTLKDGSVVGGAEDPAPFLDSWQVP---------SSLTSVGQTRFRPDSCATTDC 2232
+ +D G V A F +QV S+L S T + + A C
Sbjct: 703 NQQDDFLTPAGDVETSI---AAFASKFQVAGKGRCPSEDSALLSPCTTHSQRHAFAEAAC 759
Query: 2233 SPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYV-------QQPCVALTVYVAMCHKFH 2285
+ ++ + F CHR V E F ++R V C L+ Y C +
Sbjct: 760 A----ILHSSVFQECHRLVDKEPF---YLRCLAAVCGCDPGSDCLCPVLSAYARRCAQEG 812
Query: 2286 VCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGE---GCVCS 2342
WR CP +C Y+ C AC + C PE C LG GC C
Sbjct: 813 ASPPWRNQTLCPVMCPGGQEYRECAPAC--GQHCG-------KPEDCGELGSCVAGCNCP 863
Query: 2343 EGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGC 2402
G + C+P + C C +G R ++++ C + CQ C
Sbjct: 864 LGLLWD--PEGQCVPPSLCPC--QLGARRY--APGSATMKECNRCICQERGLWNCTARHC 917
Query: 2403 PS----PRPESCLRFGEVALLLPTKDP-----CCLGTVCVCNQTLCEGLAPTCRPGHRLL 2453
PS PR L + A LL P C G+ C C PG LL
Sbjct: 918 PSQAFCPRE---LVYAPGACLLTCDSPSANHSCPAGSTDGC----------VCPPGTVLL 964
Query: 2454 THFQEDSCCPSYSCEC 2469
++ C P C C
Sbjct: 965 ----DERCVPPDLCPC 976
Score = 66.6 bits (161), Expect = 3e-10
Identities = 78/351 (22%), Positives = 107/351 (30%), Gaps = 125/351 (35%)
Query: 674 PC-LCATLAHYAHLCRRHGLPVDFR------ARLPAC------ALSCEASKEYSPCVAPC 720
PC +C +H + C R P R + C C + PC PC
Sbjct: 3483 PCDMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTDCGGGQSLHPCGQPC 3542
Query: 721 GRTCQDLASPEAC--GVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQ-- 776
R+CQDL+ C G G C C CP +Q LCVP C C +Q
Sbjct: 3543 PRSCQDLSPGSVCQPGSVG--------CQPTCGCPLGQL--SQDGLCVPPAHCRCQYQPG 3592
Query: 777 --GV----------------DYPPGDSDIPSLGHCHCKDGVMSCD--------------- 803
G+ PG+ +C C G++ C
Sbjct: 3593 AMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCPDPGVWSSWG 3652
Query: 804 --------------------SRAPA-----------------AACPAGQVFVNCSDLHTD 826
+R P A CPAG+++ C
Sbjct: 3653 PWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCSTQVCREAGCPAGRLYRECQPGE-- 3710
Query: 827 LELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPC---TW------ 877
+C + + G C GC CP+G +H AC +ECPC W
Sbjct: 3711 ---GCPFSCAHVTQQVGCFSEG-CEEGCHCPEGTFQHRLACV--QECPCVLTAWLLQELG 3764
Query: 878 -----KGKEYFPGDQVMS------PCHTCVCQRGSFQCTLHPCASTCTAYG 917
G+ PGD++ S C C C G C+L C +G
Sbjct: 3765 ATIGDPGQPLGPGDELDSGQTLRTSCGNCSCAHGKLSCSLDDCFEADGGFG 3815
Score = 64.7 bits (156), Expect = 1e-09
Identities = 39/128 (30%), Positives = 51/128 (39%), Gaps = 12/128 (9%)
Query: 317 RALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEI 376
+ L +Y G Q + CT + Y+ C CP SC CV
Sbjct: 3285 QGLGDYCEGPRAQGEVCQALPCPVTNCTAI---EGAEYSPCGPPCPRSCDDLVHCV---W 3338
Query: 377 ACVDGCYCPNGLIFEDGG--CVAPAECPCE--FHGTLYPPGSVVK--EDCNTCTCTSGKW 430
C GCYCP G + G CV P C C G + PG+ + + CN CTC G+
Sbjct: 3339 RCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGRL 3398
Query: 431 ECSTAVCP 438
C+ CP
Sbjct: 3399 NCTDLPCP 3406
Score = 64.3 bits (155), Expect = 2e-09
Identities = 34/109 (31%), Positives = 42/109 (38%), Gaps = 8/109 (7%)
Query: 802 CDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLL 861
C+ A CPAG V C++ R C + C GC CP+G L
Sbjct: 4053 CNPMPCEAGCPAGMEVVTCAN-------RCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSL 4105
Query: 862 RHGDACFLPEECPCT-WKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPC 909
C C CT +G + PG Q C+ C CQ G CT PC
Sbjct: 4106 EQDGGCVPIGHCDCTDAQGHSWAPGSQHQDACNNCSCQAGQLSCTAQPC 4154
Score = 63.9 bits (154), Expect = 2e-09
Identities = 42/139 (30%), Positives = 55/139 (39%), Gaps = 8/139 (5%)
Query: 778 VDYPP--GDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTC 835
VD PP G + P G+ C C G+V+V+ L +C
Sbjct: 2583 VDPPPKNGGAPCPGASQERAPCGLQPCSG---GTDCELGRVYVSADLCQKGLVPPCPPSC 2639
Query: 836 EQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPG-DQVMSPCHT 894
N S S G C+ GC CP GLL H C ECPC + +PG ++ C
Sbjct: 2640 LDPKANRSCS--GHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLGNCSQ 2697
Query: 895 CVCQRGSFQCTLHPCASTC 913
CVC++G C C C
Sbjct: 2698 CVCEKGELLCQPGGCPLPC 2716
Score = 62.4 bits (150), Expect = 6e-09
Identities = 56/203 (27%), Positives = 73/203 (35%), Gaps = 39/203 (19%)
Query: 258 PRPPCLQQNPGTMQGVYEQCEALLRPPFDACHA--YVSPLPFTASCTSDLCQSMGDVATW 315
P PC + QG +C L C + S FTA+C D G+ +TW
Sbjct: 1702 PWGPCSRTCGPWGQGRSRRCSPLGLLVLQNCPGPEHQSQACFTAACPVD-----GEWSTW 1756
Query: 316 ---------CRALAEYARACAQAGRPLQGWRT------------QLRQCTVHCKEKAFTY 354
CR R C P G RT Q + C A
Sbjct: 1757 SPWSVCSEPCRGTMTRQRQCHS---PQNGGRTCAALPGGLHSTRQTKPCPQDGCPNATCS 1813
Query: 355 NECI----ACCPASCHP---RASCVDSEIACVDGCYCPNGLIF-EDGGCVAPAECPCEFH 406
E + A CP +C + +C GC+CP G + +G CV P +CPC
Sbjct: 1814 GELMFQPCAPCPLTCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSEGWCVWPRQCPCLVD 1873
Query: 407 GTLYPPGSVVKEDCNTCTCTSGK 429
G Y PG +K DC C C G+
Sbjct: 1874 GARYWPGQRIKADCQLCICQDGR 1896
Score = 62.4 bits (150), Expect = 6e-09
Identities = 34/85 (40%), Positives = 43/85 (50%), Gaps = 7/85 (8%)
Query: 361 CPASC-HPRA--SCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPG-SVV 416
CP SC P+A SC CV+GC CP GL+ D C+ +ECPC L PG S +
Sbjct: 2635 CPPSCLDPKANRSCSGH---CVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFL 2691
Query: 417 KEDCNTCTCTSGKWECSTAVCPAEC 441
+C+ C C G+ C CP C
Sbjct: 2692 LGNCSQCVCEKGELLCQPGGCPLPC 2716
Score = 62.0 bits (149), Expect = 8e-09
Identities = 36/115 (31%), Positives = 49/115 (42%), Gaps = 14/115 (12%)
Query: 798 GVMSCDSRAPAAACPAGQVFVNCSDLHTDL-ELSRERTCEQQLLNLSVSARGPCLSGCAC 856
G+ C P CP + +++C+ ELS R Q C GC C
Sbjct: 3078 GLQPCAGPVPGM-CPRDKQWLDCAQGPASCAELSAPRGTNQT-----------CHPGCHC 3125
Query: 857 PQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSF-QCTLHPCA 910
P G+L + C ++CPC +G Y PG V+ PC C C G C+ PCA
Sbjct: 3126 PSGMLLLNNVCVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPCA 3180
Score = 61.6 bits (148), Expect = 1e-08
Identities = 27/66 (40%), Positives = 31/66 (46%), Gaps = 5/66 (7%)
Query: 849 PCLSGCACPQGLLRHGDACFLPEECPC-----TWKGKEYFPGDQVMSPCHTCVCQRGSFQ 903
PC GC CP+GLL C PEEC C G PGD++ C C C+RG
Sbjct: 4454 PCQPGCYCPKGLLEQAGGCIPPEECNCWHTSAAGAGMTLAPGDRLQLGCKECECRRGELH 4513
Query: 904 CTLHPC 909
CT C
Sbjct: 4514 CTSQGC 4519
Score = 60.5 bits (145), Expect = 2e-08
Identities = 62/231 (26%), Positives = 83/231 (35%), Gaps = 38/231 (16%)
Query: 707 CEASKEYSPCVAPCGRTCQDLASPEA--CGVDG--------GDDLSRDECVEGCACPPDT 756
C A +SP PC RTC + C G G + C ACP D
Sbjct: 1694 CGAWGPWSPW-GPCSRTCGPWGQGRSRRCSPLGLLVLQNCPGPEHQSQACFTA-ACPVDG 1751
Query: 757 YLDTQADLCVPRNQC--------SCHFQGVDYPPGDSDIPSL-GHCHCKDGVMSC-DSRA 806
T + V C CH G +L G H C
Sbjct: 1752 EWSTWSPWSVCSEPCRGTMTRQRQCHSP----QNGGRTCAALPGGLHSTRQTKPCPQDGC 1807
Query: 807 PAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLS-GCACPQGLLRHGD 865
P A C +F C+ TC+ ++ PC S GC CP+G + +
Sbjct: 1808 PNATCSGELMFQPCAPCPL--------TCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSE 1859
Query: 866 A-CFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRG-SFQCTLHP-CASTC 913
C P +CPC G Y+PG ++ + C C+CQ G +C L+P CA C
Sbjct: 1860 GWCVWPRQCPCLVDGARYWPGQRIKADCQLCICQDGRPRRCRLNPDCAVDC 1910
Score = 58.2 bits (139), Expect = 1e-07
Identities = 42/137 (30%), Positives = 51/137 (37%), Gaps = 25/137 (18%)
Query: 677 CATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVD 736
CA H A LC + +P C C A E C C R C DL C D
Sbjct: 4043 CAGERHQARLC--NPMP---------CEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDD 4091
Query: 737 GGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSC-HFQGVDYPPGDSDIPSLGHCHC 795
C +GC CP + Q CVP C C QG + PG + +C C
Sbjct: 4092 -------QVCQKGCRCPKGSL--EQDGGCVPIGHCDCTDAQGHSWAPGSQHQDACNNCSC 4142
Query: 796 KDGVMSCDSRAPAAACP 812
+ G +SC A CP
Sbjct: 4143 QAGQLSC----TAQPCP 4155
Score = 53.9 bits (128), Expect = 2e-06
Identities = 29/90 (32%), Positives = 36/90 (40%), Gaps = 9/90 (10%)
Query: 356 ECIACCPASCHP---RASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGT---- 408
+C CP SC R C+ C GC CP G + +DG CV + C C
Sbjct: 4677 DCANQCPHSCADLWDRVQCLQGP--CRPGCRCPPGQLVQDGRCVPISSCRCGLPSANASW 4734
Query: 409 LYPPGSVVKEDCNTCTCTSGKWECSTAVCP 438
P V+ DC CTC + C CP
Sbjct: 4735 ELAPAQAVQLDCQNCTCVNESLVCPHQECP 4764
Score = 51.2 bits (121), Expect = 1e-05
Identities = 85/323 (26%), Positives = 111/323 (34%), Gaps = 81/323 (25%)
Query: 2296 CPFLCSSDSTYQACVTACEPPKTC---QDGILGPLDPEHCQVLGEGCVCSEGTILHRRHS 2352
CP C AC T+C P C Q G + +P CQ GC C G +LH +
Sbjct: 4815 CPE-CPPGQVLSACATSC--PCLCWHLQPGAICVQEP--CQ---PGCGCPGGQLLH---N 4863
Query: 2353 ALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVP--------------- 2397
C+P C CT +P W +L+ Q Q P T++
Sbjct: 4864 GTCVPPTACPCTQH-SLP------WGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSC 4916
Query: 2398 --VDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPT---CRPGHRL 2452
VD P + GE+ L T CL Q+ C + C+PGH
Sbjct: 4917 SLVDCQVPPGETWQQVAPGELGLCEQT----CLEMNATKTQSNCSSARASGCVCQPGH-- 4970
Query: 2453 LTHFQEDSCCPSYSCEC----DPDL--------CEAELV----PSCRQDQILITGRLGDS 2496
Q C P CEC P L CE+ L P C Q +T G+
Sbjct: 4971 -FRSQAGPCVPEDHCECWHLGRPHLPGSEWQEACESCLCLSGRPVCTQHCSPLTCAQGEE 5029
Query: 2497 CCTSYFCACGDCPDSIPECQEG--EALTVHRNTTELCCPLYQ---CVCENFRCPQVQCGL 2551
C C PE Q + LT RN T+ C L Q C + C
Sbjct: 5030 MVLEPGSCCPSCRREAPEEQSPSCQLLTELRNFTKGTCYLDQVEVSYCSGY------CPS 5083
Query: 2552 GTALVEVWSPDRCCPYKSCECDC 2574
T ++ P+ PY +CDC
Sbjct: 5084 STHVM----PEE--PYLQSQCDC 5100
Score = 50.1 bits (118), Expect = 3e-05
Identities = 42/143 (29%), Positives = 52/143 (36%), Gaps = 32/143 (22%)
Query: 323 ARACAQAGRPLQGWRTQLRQCTVH-CKEKAFT----YNECIAC--CPASC-HPRASCVDS 374
+R CA+ P G Q R C+ C+E Y EC CP SC H
Sbjct: 3669 SRRCARP--PCPGPARQSRTCSTQVCREAGCPAGRLYRECQPGEGCPFSCAHVTQQVGCF 3726
Query: 375 EIACVDGCYCPNGLIFEDGGCVAPAECPC--------EFHGTLYPPGS------------ 414
C +GC+CP G CV ECPC E T+ PG
Sbjct: 3727 SEGCEEGCHCPEGTFQHRLACVQ--ECPCVLTAWLLQELGATIGDPGQPLGPGDELDSGQ 3784
Query: 415 VVKEDCNTCTCTSGKWECSTAVC 437
++ C C+C GK CS C
Sbjct: 3785 TLRTSCGNCSCAHGKLSCSLDDC 3807
Score = 49.3 bits (116), Expect = 5e-05
Identities = 29/103 (28%), Positives = 45/103 (43%), Gaps = 12/103 (11%)
Query: 707 CEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCV 766
C K++ C A +C +L++P + C GC CP L ++CV
Sbjct: 3090 CPRDKQWLDC-AQGPASCAELSAPRG---------TNQTCHPGCHCPSGMLLLN--NVCV 3137
Query: 767 PRNQCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAA 809
P C C +G YPPG + + +C C G+++ S P A
Sbjct: 3138 PTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPCA 3180
Score = 48.9 bits (115), Expect = 7e-05
Identities = 33/115 (28%), Positives = 44/115 (38%), Gaps = 14/115 (12%)
Query: 706 SCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLC 765
SC E+ C +PC C S + C DL C GC CP L QA C
Sbjct: 4422 SCTPPFEFHACGSPCAGLCATHLSHQLC-----QDL--PPCQPGCYCPKG--LLEQAGGC 4472
Query: 766 VPRNQCSCHF-----QGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQ 815
+P +C+C G+ PGD C C+ G + C S+ P +
Sbjct: 4473 IPPEECNCWHTSAAGAGMTLAPGDRLQLGCKECECRRGELHCTSQGCQGLLPLSE 4527
Score = 47.8 bits (112), Expect = 2e-04
Identities = 71/335 (21%), Positives = 109/335 (32%), Gaps = 70/335 (20%)
Query: 608 WKTLSACSPLVSGSPLD------------PCDVH--LQAASYSVQACSVLT-GEMFAPCS 652
W S+CS G ++ PC Q ++Q C G++ + C+
Sbjct: 4769 WSAWSSCSAPCGGGTMERHRTCEGGPGVAPCQAQDTEQRQECNLQPCPECPPGQVLSACA 4828
Query: 653 AFLSPVPYFEQ----CRRDACRCGQPCLCATLAHY-------AHLCRRHGLPVDFRARL- 700
+ + Q C ++ C+ G C L H A C +H LP L
Sbjct: 4829 TSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTACPCTQHSLPWGLTLTLE 4888
Query: 701 -------PACALSCEASK----------EYSPCVAPCGRTCQDLASPE------ACGVDG 737
P L+ ++ C P G T Q +A E C ++
Sbjct: 4889 EQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQVPPGETWQQVAPGELGLCEQTC-LEM 4947
Query: 738 GDDLSRDEC----VEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHC 793
++ C GC C P + +QA CVP + C C G + PG + C
Sbjct: 4948 NATKTQSNCSSARASGCVCQPG-HFRSQAGPCVPEDHCECWHLGRPHLPGSEWQEACESC 5006
Query: 794 HCKDGVMSCDSRAPAAACPAGQVFV-----NCSDLHTDLELSRERTCEQQLLNLSVSARG 848
C G C C G+ V C + + +C Q L L +G
Sbjct: 5007 LCLSGRPVCTQHCSPLTCAQGEEMVLEPGSCCPSCRREAPEEQSPSC-QLLTELRNFTKG 5065
Query: 849 PC------LSGCA--CPQGLLRHGDACFLPEECPC 875
C +S C+ CP + +L +C C
Sbjct: 5066 TCYLDQVEVSYCSGYCPSSTHVMPEEPYLQSQCDC 5100
Score = 46.6 bits (109), Expect = 4e-04
Identities = 54/201 (26%), Positives = 66/201 (32%), Gaps = 46/201 (22%)
Query: 750 CACPPDTYLDTQADLCVPRNQ---CS--------CHFQGVDYPPGDSDIPSLGHCH--CK 796
CA P T A L +P CS C QG D G HC C
Sbjct: 3210 CARSPSAVPSTVAPLPLPATPTPLCSGPEAEEEPCLLQGCDRAGGWGPWGPWSHCSRSCG 3269
Query: 797 DGVMS----CDSRAP------------------AAACPAGQVFVNCSDLHTDLELSRERT 834
G+ S CD P A CP NC+ +
Sbjct: 3270 GGLRSRTRACDQPPPQGLGDYCEGPRAQGEVCQALPCPV----TNCTAIEGAEYSPCGPP 3325
Query: 835 CEQQLLNLSVSARGPCLSGCACPQG--LLRHGDACFLPEECPCT--WKGKEYFPGDQVMS 890
C + +L V C GC CP G L +G C P C C G+ + PG ++
Sbjct: 3326 CPRSCDDL-VHCVWRCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLAR 3384
Query: 891 P--CHTCVCQRGSFQCTLHPC 909
P C+ C C G CT PC
Sbjct: 3385 PDGCNHCTCLEGRLNCTDLPC 3405
Score = 45.4 bits (106), Expect = 8e-04
Identities = 57/226 (25%), Positives = 77/226 (34%), Gaps = 36/226 (15%)
Query: 2296 CPFLCSSDSTYQACVTACEPPKTC---QDGILGPLDPEHCQVLGEGCVCSEGTILHRRHS 2352
C C + C C P+ C Q+GI+ D QV +GC C +G++
Sbjct: 4058 CEAGCPAGMEVVTCANRC--PRRCSDLQEGIVCQDD----QVCQKGCRCPKGSL---EQD 4108
Query: 2353 ALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGC---PSPRPES 2409
C+P C CTD+ G A G + + C CQA L C P P P
Sbjct: 4109 GGCVPIGHCDCTDAQGHSWAPGSQHQDACNNC---SCQAG------QLSCTAQPCPPPTH 4159
Query: 2410 CLRFGEVALLLPTKDPC-CLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCE 2468
C + + P C G + AP CR + CP SC
Sbjct: 4160 C-AWSHWSAWSPCSHSCGPRGQQSRFRSSTSGSWAPECREEQ------SQSQPCPQPSC- 4211
Query: 2469 CDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPE 2514
P LC + S + G CT C D ++PE
Sbjct: 4212 --PPLC-LQGTRSRTLGDSWLQGECQRCSCTPEGVICEDTECAVPE 4254
Score = 44.7 bits (104), Expect = 0.001
Identities = 23/67 (34%), Positives = 30/67 (44%), Gaps = 1/67 (1%)
Query: 377 ACVDGCYC-PNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTA 435
A GC C P + G CV C C G + PGS +E C +C C SG+ C+
Sbjct: 4959 ARASGCVCQPGHFRSQAGPCVPEDHCECWHLGRPHLPGSEWQEACESCLCLSGRPVCTQH 5018
Query: 436 VCPAECS 442
P C+
Sbjct: 5019 CSPLTCA 5025
Score = 43.1 bits (100), Expect = 0.004
Identities = 26/88 (29%), Positives = 40/88 (45%), Gaps = 14/88 (15%)
Query: 717 VAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYL-DTQADLCVPRNQCSCHF 775
V PC +C D + +C CVEGC CPP L DT+ C+P ++C C
Sbjct: 2632 VPPCPPSCLDPKANRSCS---------GHCVEGCRCPPGLLLHDTR---CLPLSECPCLV 2679
Query: 776 -QGVDYPPGDSDIPSLGHCHCKDGVMSC 802
+ + +P + + C C+ G + C
Sbjct: 2680 GEELKWPGVSFLLGNCSQCVCEKGELLC 2707
Score = 35.4 bits (80), Expect = 0.81
Identities = 86/396 (21%), Positives = 118/396 (29%), Gaps = 71/396 (17%)
Query: 2229 TTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQ-QPCVALTVYVAMCHKFHVC 2287
+T +PC + R S C P ++ C T+ QPC A + C
Sbjct: 2840 STCSAPCDGGIQTRGRS-CSSLAPGDTTCPGPHSQTRDCNTQPCTAQCPENMLFRSAEQC 2898
Query: 2288 IEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGIL------GPLDPEHCQVLGEGCVC 2341
+ CP LC + C C P TC G+ P CQ+ G+
Sbjct: 2899 HQ--EGGPCPRLCLTQGPGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYAS 2956
Query: 2342 SEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNS-SLSGCCQHQCQA-------PD 2393
L ++ C+ K ACT S P A G W+ +L C C
Sbjct: 2957 GAMARLDSCNNCTCV-SGKMACT-SERCPVACG--WSPWTLWSLCSCSCNVGIRRRFRAG 3012
Query: 2394 TIVPVDLG---CPSPRPESCLRFGEVALLLPTKDPCC-LGTVCVCNQTLCEGLAPTCRPG 2449
T P G C P E+ E L P P G C + C G
Sbjct: 3013 TAPPAAFGGAECQGPTMEA-----EFCSLRPCPGPGGEWGPWSPC--------SVPCGGG 3059
Query: 2450 HRLLTHFQEDSCCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCP 2509
+R T S +C P C + C +D+ + G + C G
Sbjct: 3060 YRNRTRGSSRSLMEFSTCGLQP--CAGPVPGMCPRDKQWLDCAQGPASCAELSAPRGTNQ 3117
Query: 2510 DSIPECQEGEALTVHRNTTELCCPLYQCVC----------ENFRCPQVQCGLGTALV--- 2556
P C + + N +C P C C P C + L+
Sbjct: 3118 TCHPGCHCPSGMLLLNN---VCVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANC 3174
Query: 2557 ---------EVWSPDRCCPYKSCECDCDTIPVPRCH 2583
WSP P+ C C RCH
Sbjct: 3175 SSWPCAEGEPTWSP--WTPWSQCSASCGP---ARCH 3205
Score = 34.7 bits (78), Expect = 1.4
Identities = 31/104 (29%), Positives = 43/104 (41%), Gaps = 32/104 (30%)
Query: 2319 CQDGILGP-----LDPE-------HCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDS 2366
CQ G++ P LDP+ HC EGC C G +L H C+P ++C C
Sbjct: 2627 CQKGLVPPCPPSCLDPKANRSCSGHCV---EGCRCPPGLLL---HDTRCLPLSECPC--- 2677
Query: 2367 MGVPRALGE--TW---NSSLSGCCQHQCQAPDTIVPVDLGCPSP 2405
+GE W + L C Q C+ + + GCP P
Sbjct: 2678 -----LVGEELKWPGVSFLLGNCSQCVCEKGELLCQPG-GCPLP 2715
Score = 33.9 bits (76), Expect = 2.4
Identities = 24/78 (30%), Positives = 33/78 (42%), Gaps = 7/78 (8%)
Query: 1338 WRYDACASPCFQTCRDPRAAS-CRDVPRVEGCVPVCPTPQVLDEVTQRCVYLEDCVEPAV 1396
+ + AC SPC C + C+D+P C P C P+ L E C+ E+C
Sbjct: 4427 FEFHACGSPCAGLCATHLSHQLCQDLPP---CQPGCYCPKGLLEQAGGCIPPEEC---NC 4480
Query: 1397 WVPTEALGNETLPPSQGL 1414
W + A TL P L
Sbjct: 4481 WHTSAAGAGMTLAPGDRL 4498
Score = 32.7 bits (73), Expect = 5.3
Identities = 35/118 (29%), Positives = 47/118 (39%), Gaps = 26/118 (22%)
Query: 1727 MSLESTRPSQLL----SGLPPDTSLPLAKVGTSAPVAT----PGPKASV----------I 1768
++L S +P QLL GL P + ++P T PGP + V
Sbjct: 2285 LALSSAQPGQLLHWPREGLAETEHWPPGQESPTSPTETRPVSPGPASGVPHHGESVQMVT 2344
Query: 1769 TTPL-QPQATTLPAQTLS-------PVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLG 1818
TTP+ Q +A TLP + PV P TPA + A P G P +LG
Sbjct: 2345 TTPIPQMEARTLPPGMAAVTVVPPHPVTPATPAGQSVAPGPFPPVQCGPGQTPCEVLG 2402
Score = 32.7 bits (73), Expect = 5.3
Identities = 26/88 (29%), Positives = 38/88 (43%), Gaps = 14/88 (15%)
Query: 2300 CSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHR-RHSALCIPE 2358
C + C C P++CQD G + CQ GC + G L + LC+P
Sbjct: 3529 CGGGQSLHPCGQPC--PRSCQDLSPGSV----CQPGSVGCQPTCGCPLGQLSQDGLCVPP 3582
Query: 2359 AKCAC---TDSMGVP----RALGETWNS 2379
A C C +MG+P R+ G ++S
Sbjct: 3583 AHCRCQYQPGAMGIPENQSRSAGSRFSS 3610
>gi|151301154 mucin 6, gastric [Homo sapiens]
Length = 2439
Score = 512 bits (1318), Expect = e-144
Identities = 350/1152 (30%), Positives = 520/1152 (45%), Gaps = 87/1152 (7%)
Query: 79 CRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVS 138
C WG H TFD Y SG +Y + +FS+Q+ P S S
Sbjct: 45 CSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRRGPDGSISRIIVELGAS 104
Query: 139 LFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQ---QLAGYVIVRHQSAFTLAWDGASA 195
+ V E I + K++ G+ + LP+ ++ Q V + + + W S
Sbjct: 105 VVTVSEAIISV-KDI---GV-ISLPYTSNGLQITPFGQSVRLVAKQLELELEVVWGPDSH 159
Query: 196 VYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGP--T 253
+ + + + +G GLCGN + ++ V+ GK + H + PG T
Sbjct: 160 LMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEP-----HKFAALQKLDDPGEICT 214
Query: 254 TSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSM--GD 311
+P Q + C LL C VS PF SC +D+ + G
Sbjct: 215 FQDIPSTHVRQAQHARI------CTQLLTLVAPECS--VSKEPFVLSCQADVAAAPQPGP 266
Query: 312 VATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASC-HPRAS 370
+ C L+EY+R C+ G+P++ WR+ C+V Y EC + C +C +P+ S
Sbjct: 267 QNSSCATLSEYSRQCSMVGQPVRRWRSP-GLCSVGQCPANQVYQECGSACVKTCSNPQHS 325
Query: 371 CVDSEIACVDGCYCPNGLIFEDGG----CVAPAECPCEFHGTLYPPGSVVKEDCNTCTCT 426
C S C GC+CP G + D CV +CPC HG +Y PG V C TC CT
Sbjct: 326 CSSS---CTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTIAACQTCRCT 382
Query: 427 SGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRS---SGTFTVTLQNA 483
G+W C+ CP CS+ G TTFD R Y F TC YIL +S G +
Sbjct: 383 LGRWVCTERPCPGHCSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYDKS 442
Query: 484 PCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVF 543
G++ + +V + QD ++ ++Q V + K +P Y + R +S
Sbjct: 443 --GVSHSETSLVAVVYLSRQD---KIVISQDEVVTNNGEAKWLP-YKTRNITVFRQTSTH 496
Query: 544 LRVRTNVGVRVLYD-REGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQ 602
L++ T+ G+ ++ R + Y+ V ++ T GLCG FNG+T DDF + +G+ E T
Sbjct: 497 LQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTAS 556
Query: 603 LFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPY 660
LF +SW+ + P DPC + + CS+L TG +F C A ++P P+
Sbjct: 557 LFVDSWRAGNC--PAALERETDPCSMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPF 614
Query: 661 FEQCRRDACRCGQ--PCLCATLAHYAHLCRRHGLPV-DFRARLPACALSCEASKEYSPCV 717
+++C AC + P +CA L Y H C G+ + +R+ + C + C + +S
Sbjct: 615 YKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNS 674
Query: 718 APCGRTCQDLASPEACGVDGGDDLSRDEC------VEGCACPPDTYLDTQADLCVPRNQC 771
C RTC L+ EC V+GC CP TYL+ + + CV + QC
Sbjct: 675 QACERTCLSLSDRAT------------ECHHSAVPVDGCNCPDGTYLNQKGE-CVRKAQC 721
Query: 772 SCHFQGVDYPPGDSDIPSLG-HCHCKDGVMSCDSRAPA--AACPAGQVFVNCSDLHTD-L 827
C +G + + G CHC +G +SC R A+C A + F +CS +
Sbjct: 722 PCILEGYKFILAEQSTVINGITCHCINGRLSCPQRPQMFLASCQAPKTFKSCSQSSENKF 781
Query: 828 ELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDA-CFLPEECPCTWKGKEYFPGD 886
+ TC Q L C GC C +GL + D C PEECPC + G Y G
Sbjct: 782 GAACAPTC-QMLATGVACVPTKCEPGCVCAEGLYENADGQCVPPEECPCEFSGVSYPGGA 840
Query: 887 QVMSPCHTCVCQRGSFQCTLHP-CASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD 945
++ + C TC C RG + C C STCT YG+ H TFDG F F G C+ L
Sbjct: 841 ELHTDCRTCSCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCG 900
Query: 946 VS-----FSVIVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHT 1000
V+ F ++ ENV C +SG+ C + I I +G +V D + + E + V
Sbjct: 901 VNDSQPTFKILTENVICGNSGVTCSRAIKIFLGGLSVVLADRNYTVTGEE-PHVQLGVTP 959
Query: 1001 WRVGFFTLVHFPQEH-ITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENL 1059
+ + P + +TL+W++ T+ ++ Q L GLCGNF+ ++ T
Sbjct: 960 GALSLVVDISIPGRYNLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRY 1019
Query: 1060 ELTNPQEFGSSWAAVE-CPDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVT 1118
++ E +SW C D D C LN R +A+++CS++ S+ F CH V
Sbjct: 1020 VASSELELVNSWKESPLCGDVSFVTDPCSLNAFRRSWAERKCSVINSQTFATCHSKVYHL 1079
Query: 1119 WFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVL- 1177
+Y C+ D CGC GGDCEC C +V+AYA C GV VDWRTP CP C F+N
Sbjct: 1080 PYYEACVRDACGCDSGGDCECLCDAVAAYAQACLDKGVCVDWRTPAFCPIYCGFYNTHTQ 1139
Query: 1178 -GKGPYQLSSLA 1188
G G YQ + A
Sbjct: 1140 DGHGEYQYTQEA 1151
Score = 226 bits (577), Expect = 2e-58
Identities = 218/864 (25%), Positives = 335/864 (38%), Gaps = 197/864 (22%)
Query: 79 CRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVS 138
C G V TFD Y G +Y L+ + + V++ + G S S
Sbjct: 397 CSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYD--KSGVSHSETSLVAV 454
Query: 139 LFFVGEQEIHLAKE--VTHGGMRVQLPHV--------MGSARLQQLAGY---VIVRHQSA 185
++ + +I ++++ VT+ G LP+ S LQ + ++V+ +
Sbjct: 455 VYLSRQDKIVISQDEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQLRPI 514
Query: 186 FTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQE-- 243
F Y+ + P+ G T GLCGN N D DD TS G FV SW+
Sbjct: 515 FQ--------AYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWRAGN 566
Query: 244 --QAPNQPPGPTTSSLPRPPCLQQNPGTMQG---VYEQCEALLRPP-------FDACHAY 291
A + P + S C + + + V+E+C A + P + AC+ Y
Sbjct: 567 CPAALERETDPCSMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQACN-Y 625
Query: 292 VSPLPF-----------------------------TASCTSDL------------CQSMG 310
P T CT + C S+
Sbjct: 626 EETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLSLS 685
Query: 311 DVATWCRALAEYARAC-----------------AQAGRPLQGWR-------TQLRQCTVH 346
D AT C A C AQ L+G++ T + T H
Sbjct: 686 DRATECHHSAVPVDGCNCPDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVINGITCH 745
Query: 347 C---------KEKAF--------TYNECIACCP----ASCHPRASCVDSEIACVD----- 380
C + + F T+ C A+C P + + +ACV
Sbjct: 746 CINGRLSCPQRPQMFLASCQAPKTFKSCSQSSENKFGAACAPTCQMLATGVACVPTKCEP 805
Query: 381 GCYCPNGLIFE-DGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTAV-CP 438
GC C GL DG CV P ECPCEF G YP G+ + DC TC+C+ G+W C CP
Sbjct: 806 GCVCAEGLYENADGQCVPPEECPCEFSGVSYPGGAELHTDCRTCSCSRGRWACQQGTHCP 865
Query: 439 AECSVTGDIHFTTFDGRRYTFPATCQYILAK-----SRSSGTFTVTLQNAPCGLNQDGAC 493
+ C++ G+ H TFDG+R+ F C+YILA + S TF + +N CG N C
Sbjct: 866 STCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPTFKILTENVICG-NSGVTC 924
Query: 494 VQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVR 553
+++ + L V L + ++ + T A + V + + +
Sbjct: 925 SRAIKIFLGG---LSVVLADRNYTVTGEEPHVQLGVTPGALSL----VVDISIPGRYNLT 977
Query: 554 VLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA 613
++++R + + +++ + + GLCG FNGN +DDF + S+ NSWK
Sbjct: 978 LIWNRH-MTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSWKESPL 1036
Query: 614 CSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQ 673
C + DPC ++ S++ + CSV+ + FA C + + +PY+E C RDAC C
Sbjct: 1037 CGDV--SFVTDPCSLNAFRRSWAERKCSVINSQTFATCHSKVYHLPYYEACVRDACGCDS 1094
Query: 674 ----PCLCATLAHYAHLCRRHGLPVDFRARLPA-CALSC--------------------E 708
CLC +A YA C G+ VD+R PA C + C
Sbjct: 1095 GGDCECLCDAVAAYAQACLDKGVCVDWRT--PAFCPIYCGFYNTHTQDGHGEYQYTQEAN 1152
Query: 709 ASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCA-CPPDTYLDTQADLCVP 767
+ Y PC+ P + P++ V G + +EGC C D Y D + +CVP
Sbjct: 1153 CTWHYQPCLCP--------SQPQS--VPGSN-------IEGCYNCSQDEYFDHEEGVCVP 1195
Query: 768 RNQCSCHFQGVDYPPGDSDIPSLG 791
C PP +P+ G
Sbjct: 1196 -----CMPPTTPQPPTTPQLPTTG 1214
Score = 118 bits (295), Expect = 1e-25
Identities = 114/402 (28%), Positives = 172/402 (42%), Gaps = 43/402 (10%)
Query: 434 TAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSG--TFTVTLQNAPCGLNQDG 491
TA +CS G HF+TFD Y F TC YI A + TF+V L+ P G
Sbjct: 38 TAPDKGQCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRRGPDG----- 92
Query: 492 ACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRL--SSVFLRVRTN 549
S+S I+ + VT+++A + + D I PYT + +I S + +
Sbjct: 93 ----SISRIIVELGASVVTVSEA-IISVKDIGVISLPYTSNGLQITPFGQSVRLVAKQLE 147
Query: 550 VGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWK 609
+ + V++ + L + V+++++ GLCG F+G ++F+S G P F K
Sbjct: 148 LELEVVWGPDS-HLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEG-KFLEPHKFAALQK 205
Query: 610 TLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDAC 669
P + D H++ A ++ + C+ L + CS +S P+ C+ D
Sbjct: 206 ---LDDPGEICTFQDIPSTHVRQAQHA-RICTQLLTLVAPECS--VSKEPFVLSCQADVA 259
Query: 670 RCGQP----CLCATLAHYAHLCRRHGLPVDFRARLPA-CAL-SCEASKEYSPCVAPCGRT 723
QP CATL+ Y+ C G PV R R P C++ C A++ Y C + C +T
Sbjct: 260 AAPQPGPQNSSCATLSEYSRQCSMVGQPVR-RWRSPGLCSVGQCPANQVYQECGSACVKT 318
Query: 724 CQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQAD--LCVPRNQCSCHFQGVDYP 781
C + +C C GC CP T L+ ++ CVP QC C G Y
Sbjct: 319 CSN--PQHSCS---------SSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYA 367
Query: 782 PGDSDIPSLGHCHCKDGVMSCDSR-APAAACPAGQVFVNCSD 822
PG+ I + C C G C R P G FV D
Sbjct: 368 PGEVTIAACQTCRCTLGRWVCTERPCPGHCSLEGGSFVTTFD 409
Score = 111 bits (277), Expect = 1e-23
Identities = 117/426 (27%), Positives = 164/426 (38%), Gaps = 67/426 (15%)
Query: 32 KCAPSYLFSCFNG------GECVHPAFCDCRRFNATGP---------------RCQMVYN 70
KC P + C G G+CV P C C + P R +
Sbjct: 802 KCEPGCV--CAEGLYENADGQCVPPEECPCEFSGVSYPGGAELHTDCRTCSCSRGRWACQ 859
Query: 71 AGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLV----GRHEPEGQSFSIQVHNDPQC 126
G S C +G+ HV TFDG + G Y L G ++ + +F I N C
Sbjct: 860 QGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQ-PTFKILTEN-VIC 917
Query: 127 GSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAF 186
G+S TCSRA+ +F G + + T G + PHV L+ V + +
Sbjct: 918 GNSGVTCSRAIKIFLGGLSVVLADRNYTVTG---EEPHVQLGVTPGALSLVVDISIPGRY 974
Query: 187 --TLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQ 244
TL W+ + I+++ GLCGN N + KDD T S + +E V+SW+E
Sbjct: 975 NLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSWKES 1034
Query: 245 APNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSD 304
P S PC N +C + F CH+ V LP+ +C D
Sbjct: 1035 -----PLCGDVSFVTDPC-SLNAFRRSWAERKCSVINSQTFATCHSKVYHLPYYEACVRD 1088
Query: 305 L--CQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHC---------KEKAFT 353
C S GD C A+A YA+AC G + WRT C ++C +
Sbjct: 1089 ACGCDSGGDCECLCDAVAAYAQACLDKGVCVD-WRTP-AFCPIYCGFYNTHTQDGHGEYQ 1146
Query: 354 YNECIACC----PASCHPRASCVDSEIACVDGCY-CPNGLIF--EDGGCVAPAECPCEFH 406
Y + C P C + V + ++GCY C F E+G CV PC
Sbjct: 1147 YTQEANCTWHYQPCLCPSQPQSVPG--SNIEGCYNCSQDEYFDHEEGVCV-----PCMPP 1199
Query: 407 GTLYPP 412
T PP
Sbjct: 1200 TTPQPP 1205
Score = 94.7 bits (234), Expect = 1e-18
Identities = 176/738 (23%), Positives = 253/738 (34%), Gaps = 116/738 (15%)
Query: 1336 CEWRYDACASPCFQTCRDPRAASCRDVP--RVEGCVPVCPTPQVLDEVTQRCVYLEDCVE 1393
C W Y C P + + VP +EGC C + D CV C+
Sbjct: 1153 CTWHYQPCLCP----------SQPQSVPGSNIEGCYN-CSQDEYFDHEEGVCV---PCMP 1198
Query: 1394 PAVWVP--TEALGNETLPPSQ-----------GLPTPSDEEPQLSQESPRTPTHRP---- 1436
P P T L P+Q GL + + P S +P +PT P
Sbjct: 1199 PTTPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPS-SNHTPASPTQTPLLPA 1257
Query: 1437 ALTPAAPLTTALNPP-VTATEEPVVSPG--PTQTTLQQPLELTASQLPAGPTESPASKGV 1493
LT + P ++ PP T P + G PT T + T +Q T S AS
Sbjct: 1258 TLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATASTASPAT 1317
Query: 1494 TASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSR---SPPAP 1550
T++ + T + P T S E T P T +S + P P
Sbjct: 1318 TSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGPTTPQP 1377
Query: 1551 RFPLMTKAVTVRGHGSLPVRTTPPQPSLTASP--SSRPVASPGAISRS--------PTSS 1600
P A + TTP P T SP + PV S G ++ + PT S
Sbjct: 1378 GQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPTPS 1437
Query: 1601 GSH-----------KAVLTPAVTKVISRTGVPQPTQAQSASSPS------TPLTVAGTAA 1643
+++TP+ VI+ T T A + S+P+ T L G+
Sbjct: 1438 HPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKATGSTH 1497
Query: 1644 EQVPVSPL--ATRSLEIVLSTEKGEAG-HS------QPMGSPASP---QPHPLPSAPPRP 1691
P++P T ST K HS P +P S P+P + P
Sbjct: 1498 TAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTP 1557
Query: 1692 AQHTTMATRSPALPPET----PAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSL 1747
HT AT S PP T P +S ++T + AT F + +T P+ P T+L
Sbjct: 1558 VAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT-TTTYPTP----SHPQTTL 1612
Query: 1748 PLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHPPTHIAP- 1806
P S + T P + TP Q T + P P +A TH AP
Sbjct: 1613 PTHVPPFSTSLVT--PSTHTVITPTHAQMATSASIHSMPTGTIPPPTTLKATGSTHTAPT 1670
Query: 1807 ---PAAGTAPGLLLGATLPTSGVLPV-------AEGTA-SMVSVVPRKSTTG--KVAILS 1853
+GT+ L T TS L AE T+ S ++ P ++TG + + +
Sbjct: 1671 MTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTT 1730
Query: 1854 KQVSLPTSMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVP--TSYALSRVSAR 1911
S S + +A+ T + H T PE T P TS A
Sbjct: 1731 SGTSQSRSSFSTAK------TSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAH 1784
Query: 1912 TAPQDSMLVLLPQLAEAHGTSAGPHLAAEPVD----EATTEPSGRSAPALSIVEGLAEAL 1967
T S + P + T P + PV + TT S P ++ +
Sbjct: 1785 TTSATSSRLPTPFTTHSPPTGTTPISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFS 1844
Query: 1968 ATTTEANTSTTCVPIAEQ 1985
+ +T T +P Q
Sbjct: 1845 TSLVTPSTHTVIIPTHTQ 1862
Score = 94.4 bits (233), Expect = 1e-18
Identities = 146/606 (24%), Positives = 231/606 (38%), Gaps = 63/606 (10%)
Query: 1411 SQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTTLQ 1470
SQ + S + S S + TH P +TP + T NP T T PV + T+ +
Sbjct: 1510 SQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTN-SATSSR 1568
Query: 1471 QPLELTASQLPAGPTESPASKGVTASLLAIPHT-PESSSLPVALQTPTPGMVSGAMETTR 1529
P T P G + ++ +TA+ T P S L T P + + +
Sbjct: 1569 PPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPST 1628
Query: 1530 VTVIFAGSPNITVSS--RSPPAPRFPLMTKAVTVRGHGSLPVRTTPPQPSLTASPSSRPV 1587
TVI + S+ S P P T T++ GS T P +LT S +S+ +
Sbjct: 1629 HTVITPTHAQMATSASIHSMPTGTIPPPT---TLKATGS---THTAPTMTLTTSGTSQAL 1682
Query: 1588 ASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV-PQPTQAQSASSPSTPLTVAGTAAEQV 1646
+S +++ TS SH + A S T + P PT S +P +T +GT+ +
Sbjct: 1683 SSLNT-AKTSTSLHSHTSSTHHAEATSTSTTNITPNPT---STGTPPMTVTTSGTSQSR- 1737
Query: 1647 PVSPLATRSLEIVLSTEKGEAGHSQPMG-SPASPQPHPLPSAPPRPAQHTTMATRSPALP 1705
S +T L + H + S S P+ + P HTT AT S
Sbjct: 1738 --SSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPT 1795
Query: 1706 PET----PAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAPVATP 1761
P T P + ++T + AT F + +T P+ P T+LP S + TP
Sbjct: 1796 PFTTHSPPTGTTPISSTGPVTATSFQT-TTTYPTP----SHPHTTLPTHVPSFSTSLVTP 1850
Query: 1762 GPKASVITTPLQPQAT----TLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLL 1817
+I T Q + ++P T+ P P T A H + P +GT+
Sbjct: 1851 STHTVIIPTHTQMATSASIHSMPTGTIPP--PTTIKATGSTHTAPPMTPTTSGTSQSPSS 1908
Query: 1818 GATLPTSGVLPVAEGT--------ASMVSVVPRKSTTGKVAILSKQVS-----LPTSM-- 1862
+T TS LP + S ++ P+ ++TG ++ S LPT
Sbjct: 1909 FSTAKTSTSLPYHTSSTHHPEVTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTT 1968
Query: 1863 ----YGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPV---PTSYALSRVSARTAPQ 1915
GS+ T ATS T P Q T LP P S +L S T
Sbjct: 1969 HSPPTGSSPFSSTGPMTATSFQTTTTYPTPSHPQ--TTLPTHVPPFSTSLVTPSTHTV-- 2024
Query: 1916 DSMLVLLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSI-VEGLAEALATTTEAN 1974
++ Q+A + + P P S +AP +++ G ++ ++ + A
Sbjct: 2025 --IITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPPMTVTTSGTSQTHSSFSTAT 2082
Query: 1975 TSTTCV 1980
S++ +
Sbjct: 2083 ASSSFI 2088
Score = 92.8 bits (229), Expect = 4e-18
Identities = 128/530 (24%), Positives = 195/530 (36%), Gaps = 74/530 (13%)
Query: 1972 EANTSTTCVPIAEQDCVRHICLEGQ-LIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCC 2030
+ + + TCVP+ + CV H + + + Q C RC + G C
Sbjct: 344 DLSNNHTCVPVTQCPCVLHGAMYAPGEVTIAACQTC-------RCTL--------GRWVC 388
Query: 2031 PLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSP---DEMLTVHVLDCKSANLGH 2087
C CS+ TFD YIL QSP ++ + V D + + H
Sbjct: 389 TERPCPGHCSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYD--KSGVSH 446
Query: 2088 LNWPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRI--EDTGHMYMILT 2145
+V L+ ++ I + + VT + + W P + + + H+ M +
Sbjct: 447 SETSLVAVVYLSRQD---KIVISQ-DEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATS 502
Query: 2146 PSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFL 2205
+ L V + Q GLCG +GD +D T G G A + F+
Sbjct: 503 FGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTA---SLFV 559
Query: 2206 DSWQV------------PSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRTFSACHRFVPP 2253
DSW+ P S++ + + CA T CS LR + F CH V P
Sbjct: 560 DSWRAGNCPAALERETDPCSMSQLNKV------CAETHCSMLLR--TGTVFERCHATVNP 611
Query: 2254 ESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCI-EWRRS-DYCPFLCSSDSTYQ 2307
F + + ++ C AL YV C V + WR S D C C+ ++T+
Sbjct: 612 APFYKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFS 671
Query: 2308 ACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSM 2367
ACE +TC + H V +GC C +GT L+++ C+ +A+C C
Sbjct: 672 YNSQACE--RTCLSLSDRATECHHSAVPVDGCNCPDGTYLNQKGE--CVRKAQCPCI-LE 726
Query: 2368 GVPRALGE---TWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRP-ESCLRFGE---VALLL 2420
G L E N C + P C +P+ +SC + E A
Sbjct: 727 GYKFILAEQSTVINGITCHCINGRLSCPQRPQMFLASCQAPKTFKSCSQSSENKFGAACA 786
Query: 2421 PTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCECD 2470
PT G CV T CE P C L + + C P C C+
Sbjct: 787 PTCQMLATGVACV--PTKCE---PGCVCAEGLYEN-ADGQCVPPEECPCE 830
Score = 76.6 bits (187), Expect = 3e-13
Identities = 68/270 (25%), Positives = 113/270 (41%), Gaps = 23/270 (8%)
Query: 908 PCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSSGMICRKF 967
P C+ +G H+ TFD +DF G C ++ +T +F + G I R
Sbjct: 40 PDKGQCSTWGAGHFSTFDHHVYDFSGTCN-YIFAATCKDAFPTFSVQLRRGPDGSISRII 98
Query: 968 IS-----INVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQ 1022
+ + V ++I D P + + ++ + + + + ++W
Sbjct: 99 VELGASVVTVSEAIISVKDIGVISLP--YTSNGLQITPFGQSVRLVAKQLELELEVVWGP 156
Query: 1023 RTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTLDP 1082
+ + V ++ GQ+ GLCGNFD K NE + E + P +F AA++ D DP
Sbjct: 157 DSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEG-KFLEPHKF----AALQKLD--DP 209
Query: 1083 RDMCVLNPL-----REPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDC 1137
++C + R+ + C+ LL+ V C V F +C D Q G
Sbjct: 210 GEICTFQDIPSTHVRQAQHARICTQLLTLVAPECS--VSKEPFVLSCQADVAAAPQPGPQ 267
Query: 1138 ECFCASVSAYAHQCCQHGVAV-DWRTPRLC 1166
CA++S Y+ QC G V WR+P LC
Sbjct: 268 NSSCATLSEYSRQCSMVGQPVRRWRSPGLC 297
Score = 75.1 bits (183), Expect = 9e-13
Identities = 124/521 (23%), Positives = 202/521 (38%), Gaps = 76/521 (14%)
Query: 1407 TLPPSQGLPTPSDEEPQLSQESPRTPT-----HRPALTPAAPLTTALNPPVTATEEPVVS 1461
T+PP PT P TPT P+ A +T+L ++T P V+
Sbjct: 1876 TIPP----PTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVT 1931
Query: 1462 PGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMV 1521
P T T + T ++ P T S +S + H+P + S P + P M
Sbjct: 1932 PTST-TNITPKHTSTGTRTPVAHTTSASSSRLPTPFTT--HSPPTGSSPFSSTGP---MT 1985
Query: 1522 SGAMETTRVTVIFAGSPNITVSSRSPPAPR-----------FPLMTKAVTVRGHGSLPVR 1570
+ + +TT T P T+ + PP T+ T S P
Sbjct: 1986 ATSFQTT-TTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTG 2044
Query: 1571 TTPPQPSLTASPSSRPVASPGAISRSPTS-SGSHKAVLTPAVTKVISRTGVPQPTQAQSA 1629
T PP +L A+ S+ A P ++ S TS + S + T + + + S + +PQ + S+
Sbjct: 2045 TVPPPTTLKATGSTH-TAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNS---SS 2100
Query: 1630 SSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPH-PLPSAP 1688
PS+P+T Q+P LS+ + + S SP P P +
Sbjct: 2101 RPPSSPITT------QLP-----------HLSSATTPVSTTNQLSSSFSPSPSAPSTVSS 2143
Query: 1689 PRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLP 1748
P+ H++ T SP S+ T++ ++A + S+ LS P S+
Sbjct: 2144 YVPSSHSSPQTSSP----------SVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVS 2193
Query: 1749 LAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPA 1808
+ + S+P A+ +A++ T P TLS +LP + ++ P +H+A
Sbjct: 2194 ASPLFPSSPAASTTIRATLPHTISSP-------FTLSALLPISTVTVSPT-PSSHLASST 2245
Query: 1809 AGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTS---MYGS 1865
A+ T+ T+ S+ R T+G V++ S +PTS +
Sbjct: 2246 IAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNLTT 2305
Query: 1866 AEGGPTELTPATSHPLTPLVAE---PEGAQAGT-ALPVPTS 1902
GPT L+P T + L A P A + P PTS
Sbjct: 2306 RHPGPT-LSPTTRFLTSSLTAHGSTPASAPVSSLGTPTPTS 2345
Score = 55.1 bits (131), Expect = 1e-06
Identities = 70/288 (24%), Positives = 107/288 (37%), Gaps = 47/288 (16%)
Query: 2119 DLQPVWPPVSRYGFRIEDTGHMYMILTPS---DIQIQWLHSSGLMIVEASKTSKAQGHGL 2175
D+ + P + G +I G ++ ++++ W S LM++ K Q GL
Sbjct: 117 DIGVISLPYTSNGLQITPFGQSVRLVAKQLELELEVVWGPDSHLMVLVERKYM-GQMCGL 175
Query: 2176 CGICDGDAANDLTLKDG--------SVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSC 2227
CG DG N+ ++G + + +DP +PS T V Q +
Sbjct: 176 CGNFDGKVTNEFVSEEGKFLEPHKFAALQKLDDPGEICTFQDIPS--THVRQAQH----- 228
Query: 2228 ATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP------CVALTVYVAMC 2281
C+ L +V A V E F D QP C L+ Y C
Sbjct: 229 -ARICTQLLTLV------APECSVSKEPFVLSCQADVAAAPQPGPQNSSCATLSEYSRQC 281
Query: 2282 HKFHVCI-EWRRSDYCPF-LCSSDSTYQACVTACEPPKTCQDGILGPLDPEH--CQVLGE 2337
+ WR C C ++ YQ C +AC KTC +P+H
Sbjct: 282 SMVGQPVRRWRSPGLCSVGQCPANQVYQECGSAC--VKTCS-------NPQHSCSSSCTF 332
Query: 2338 GCVCSEGTILH-RRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGC 2384
GC C EGT+L+ ++ C+P +C C G A GE ++ C
Sbjct: 333 GCFCPEGTVLNDLSNNHTCVPVTQCPCV-LHGAMYAPGEVTIAACQTC 379
Score = 51.2 bits (121), Expect = 1e-05
Identities = 84/384 (21%), Positives = 129/384 (33%), Gaps = 92/384 (23%)
Query: 1975 TSTTCVPI-AEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLW 2033
T CVP E CV C EG L Q P P C G++ G +
Sbjct: 794 TGVACVPTKCEPGCV---CAEG-LYENADGQCVPPEECP--CEFSGVSYPGGAELHTDCR 847
Query: 2034 ECACR---------------CSIFPDLSFVTFDGSHVALFKEAIYIL---------SQSP 2069
C+C C+++ + +TFDG YIL SQ
Sbjct: 848 TCSCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPT 907
Query: 2070 DEMLTVHVL------DCKSANLGHLNWPPFCLVMLNMT------HLAHQVTIDRFNRKVT 2117
++LT +V+ C A L L N T H+ VT + V
Sbjct: 908 FKILTENVICGNSGVTCSRAIKIFLGGLSVVLADRNYTVTGEEPHVQLGVTPGALSLVVD 967
Query: 2118 VDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCG 2177
+ + RY + HM +++ ++ S+ GLCG
Sbjct: 968 ISIP------GRYNLTLIWNRHM------------------TILIRIARASQDPLCGLCG 1003
Query: 2178 ICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSC---------A 2228
+G+ +D + V A ++SW+ G F D C A
Sbjct: 1004 NFNGNMKDDFETRSRYV---ASSELELVNSWK---ESPLCGDVSFVTDPCSLNAFRRSWA 1057
Query: 2229 TTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP------CVALTVYVAMCH 2282
CS +++++TF+ CH V + E +RD C A+ Y C
Sbjct: 1058 ERKCS----VINSQTFATCHSKVYHLPYYEACVRDACGCDSGGDCECLCDAVAAYAQACL 1113
Query: 2283 KFHVCIEWRRSDYCPFLCSSDSTY 2306
VC++WR +CP C +T+
Sbjct: 1114 DKGVCVDWRTPAFCPIYCGFYNTH 1137
Score = 33.9 bits (76), Expect = 2.4
Identities = 18/66 (27%), Positives = 30/66 (45%), Gaps = 3/66 (4%)
Query: 2787 VNLVSCDGRCPSASIYNYNINTYARFCKCCREVGLQRRSVQLFC---ATNATWVPYTVQE 2843
V + C+G C SA+ +N C CCR + + ++L C +T + T+Q
Sbjct: 2367 VTVTRCEGACISAASFNIITQQVDARCSCCRPLHSYEQQLELPCPDPSTPGRRLVLTLQV 2426
Query: 2844 PTDCAC 2849
+ C C
Sbjct: 2427 FSHCVC 2432
>gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo
sapiens]
Length = 2134
Score = 476 bits (1226), Expect = e-133
Identities = 288/932 (30%), Positives = 447/932 (47%), Gaps = 65/932 (6%)
Query: 275 EQCEALLRPPFDACHAYVS-PLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGR-P 332
+ C ++ F+ C + + C + CQ+ +T C +E +R CA G
Sbjct: 687 QHCNKIIGTYFEKCGKVAALSNDYKMICIDEYCQTRDKTST-CDTYSELSRLCASDGPGT 745
Query: 333 LQGWRTQLRQC--TVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIF 390
+ WR+ T C E+ Y EC PA+C A DSE CV GC CP G +
Sbjct: 746 FESWRSDSDVVCETQRCPEQHI-YKECGPSNPATCSNVAPFQDSE--CVSGCTCPEGYLL 802
Query: 391 ED----GGCVAPAECPCEFHGTLYPPGSVVKEDCNT-CTCTSGKWECSTAVCPAECSVTG 445
+D G CV AECPCE GT+Y PG V + C + CTC KW C+ A+CP C V G
Sbjct: 803 DDIGEKGKCVLKAECPCESSGTVYQPGEVREGPCGSQCTCQDAKWSCTEALCPGRCKVEG 862
Query: 446 DIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDP 505
TTFDG +Y FP C ++ + ++++++ PC Q G C+ SV+++L+
Sbjct: 863 S-SLTTFDGVKYNFPGNCHFLAVHNED---WSISVELRPCPSGQTGTCLNSVTLLLNSSV 918
Query: 506 RRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRV-LYDREGLRLY 564
+ + + D+ + Y D +I SS +L+V T V++ + ++LY
Sbjct: 919 PVDKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASSSYLQVETYFHVKLQIQIVPVMQLY 978
Query: 565 LQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLD 624
+ + DTVGLCG++N +DDF+S + E T Q F NSW+ +S G+P
Sbjct: 979 VSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMSC----PKGNP-S 1033
Query: 625 PCDVHLQAASYSVQACSVLTGEM--FAPCSAFLSPVPYFEQCRRDACRC--GQPCLCATL 680
C + ++ ++ + C +L A C ++P PY E+C++ C C Q CLC L
Sbjct: 1034 SC-ISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTIL 1092
Query: 681 AHYAHLC-RRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPE-ACGVDGG 738
+Y C + V +R L C SC + + V C +C+ L+ + +C V+
Sbjct: 1093 GNYVKACAEKETYIVGWRTGL--CEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVE-- 1148
Query: 739 DDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCHCKDG 798
D V+GC CP Y + + + CV ++QC C+ PG C C+DG
Sbjct: 1149 -----DVPVDGCTCPDAMYQNNEGN-CVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDG 1202
Query: 799 VMSCDSRAPAAA--CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARG-PCLSGCA 855
++ C C G +V+CSD + RTC + N+ V PC GC
Sbjct: 1203 ILLCQIPIDLTLQNCSGGAEYVDCSD--PKAQRRTNRTCSTR--NIPVFDENLPCKRGCF 1258
Query: 856 CPQGLLRHGDA-CFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCT 914
CP+G++R+ C P +CPC++ G+EY G C+ C C +GS+ CT + C + C
Sbjct: 1259 CPEGMVRNSKGICVFPNDCPCSFGGREYDEGSVTSVGCNECTCIKGSWSCTQNECQTICH 1318
Query: 915 AYGDRHYRTFDGLPFDFVGACKVHLVKST---SDVSFSVIVENVNCYSSGMICRKFISIN 971
YG+ H RTFDG + F G C+ ++ + +F ++ E+V C G+ C + I +
Sbjct: 1319 IYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHENGTFRILTESVPCCEDGLTCSRKIIVA 1378
Query: 972 VGNSLIVFDDDSGNPSPESFLDDKQ--------EVHTWRVGFFTLVHFPQEHITLLWDQR 1023
+ IV D G + + K+ +HT VG + ++ F Q I ++WD+
Sbjct: 1379 FQDQNIVLQD--GKVTAVKSTESKKCELNANAYSIHT--VGLYLILKF-QNGIIVIWDKN 1433
Query: 1024 TTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSW-AAVECPDTLDP 1082
T + V P W G++ GLCGN + ++ T + + EFG+SW + EC DT+
Sbjct: 1434 TRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQ 1493
Query: 1083 RDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCA 1142
C NP + +A ++C IL F CH VD + ++ C+ + C C G FC
Sbjct: 1494 TFPCDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCT 1553
Query: 1143 SVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFN 1174
+V+ YA C GV V WR P LCP CD++N
Sbjct: 1554 AVAMYAEACSAVGVCVSWRKPNLCPVYCDYYN 1585
Score = 211 bits (537), Expect = 8e-54
Identities = 140/455 (30%), Positives = 201/455 (44%), Gaps = 41/455 (9%)
Query: 373 DSEIACVDGCYCPNGLIFEDGG-CVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWE 431
D + C GC+CP G++ G CV P +CPC F G Y GSV CN CTC G W
Sbjct: 1248 DENLPCKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYDEGSVTSVGCNECTCIKGSWS 1307
Query: 432 CSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKS---RSSGTFTVTLQNAPCGLN 488
C+ C C + G+ H TFDG+ Y+F CQY + +GTF + ++ PC
Sbjct: 1308 CTQNECQTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHENGTFRILTESVPCC-- 1365
Query: 489 QDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIP-PYTDDAFEIRRLSSVFLRVR 547
+DG ++ QD Q + Q G V + +A+ I + ++L ++
Sbjct: 1366 EDGLTCSRKIIVAFQD---QNIVLQDGKVTAVKSTESKKCELNANAYSIHTVG-LYLILK 1421
Query: 548 TNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNS 607
G+ V++D+ RL + +D W GLCG NG+ +DDF + S FGNS
Sbjct: 1422 FQNGIIVIWDKN-TRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNS 1480
Query: 608 WKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRD 667
WKT CS V+ + PCD + +++V+ C +L F C + P Y + C +
Sbjct: 1481 WKTSQECSDTVAQT--FPCDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEE 1538
Query: 668 ACRCGQPC----LCATLAHYAHLCRRHGLPVDFRARLPACALSC-------EASKEYSPC 716
AC C C +A YA C G+ V +R + C + C E Y PC
Sbjct: 1539 ACACDMEGKYLGFCTAVAMYAEACSAVGVCVSWR-KPNLCPVYCDYYNAPGECRWHYEPC 1597
Query: 717 VAPCGRTCQDLASPEACGVDGGDDLSRDECVEGC--ACPPDT-YLDTQADLCVPRNQCSC 773
+TC+D G S +EGC CP YLD CV ++CSC
Sbjct: 1598 GTVTAKTCKDQLV--------GQKFS--SLLEGCYAKCPDSAPYLDENTMKCVSLSECSC 1647
Query: 774 HFQGVDYPPGDSDIPSLGH-CHCKDGVMSCDSRAP 807
+ V P G + G C+C G + C AP
Sbjct: 1648 FYNDV-IPAGGVIEDNCGRTCYCIAGQLECSETAP 1681
Score = 132 bits (333), Expect = 4e-30
Identities = 107/380 (28%), Positives = 167/380 (43%), Gaps = 34/380 (8%)
Query: 74 ERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRH-EPEGQSFSIQVHNDPQCGSSPYT 132
E +IC +G+ HV TFDG Y G Y+ + + E +F I + P C T
Sbjct: 1312 ECQTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHENGTFRILTESVPCCEDG-LT 1370
Query: 133 CSRAVSLFFVGEQEIHLAKEVTH----GGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTL 188
CSR + + F + + +VT + +L + + + Y+I++ Q+ +
Sbjct: 1371 CSRKIIVAFQDQNIVLQDGKVTAVKSTESKKCELN--ANAYSIHTVGLYLILKFQNGIIV 1428
Query: 189 AWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQ 248
WD + + + + P G GLCGNNN D KDD T + +EF +SW+ +Q
Sbjct: 1429 IWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWK---TSQ 1485
Query: 249 PPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSD--LC 306
T + PC NP +CE L F CH V P + C + C
Sbjct: 1486 ECSDTVAQ--TFPC-DSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACAC 1542
Query: 307 QSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCK------EKAFTYNECIAC 360
G +C A+A YA AC+ G WR + C V+C E + Y C
Sbjct: 1543 DMEGKYLGFCTAVAMYAEACSAVG-VCVSWR-KPNLCPVYCDYYNAPGECRWHYEPCGTV 1600
Query: 361 CPASCHPRASCVDSEI-ACVDGCY--CPNGLIFEDGG---CVAPAECPCEFHGTLYPPGS 414
+C + V + + ++GCY CP+ + D CV+ +EC C F+ + P G
Sbjct: 1601 TAKTC--KDQLVGQKFSSLLEGCYAKCPDSAPYLDENTMKCVSLSECSC-FYNDVIPAGG 1657
Query: 415 VVKEDC-NTCTCTSGKWECS 433
V++++C TC C +G+ ECS
Sbjct: 1658 VIEDNCGRTCYCIAGQLECS 1677
Score = 111 bits (277), Expect = 1e-23
Identities = 114/451 (25%), Positives = 164/451 (36%), Gaps = 83/451 (18%)
Query: 33 CAPSYLFSCFNG-GECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRA--------W- 82
C YL G+CV A C C VY G R+ C + W
Sbjct: 796 CPEGYLLDDIGEKGKCVLKAECPCESSGT-------VYQPGEVREGPCGSQCTCQDAKWS 848
Query: 83 -------GQHHVE-----TFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSP 130
G+ VE TFDG+ Y G + V + +SI V P
Sbjct: 849 CTEALCPGRCKVEGSSLTTFDGVKYNFPGNCHFLAV-----HNEDWSISVELRPCPSGQT 903
Query: 131 YTCSRAVSLFF-----VGEQEIHLAKEVTHGGMRVQ-------LPHVMGSARLQQLAGYV 178
TC +V+L V + + VT+ +R Q + S+ Q+ Y
Sbjct: 904 GTCLNSVTLLLNSSVPVDKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASSSYLQVETYF 963
Query: 179 IVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFV 238
V+ Q +Y+ M P T GLCG+ N +DD ++S L F
Sbjct: 964 HVKLQIQIVPVMQ----LYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFA 1019
Query: 239 HSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQ------CEALL--RPPFDACHA 290
+SW+ + C + NP + + ++ C LL P +CH
Sbjct: 1020 NSWEMMS----------------CPKGNPSSCISIEKEKFAERHCGILLDSSGPLASCHP 1063
Query: 291 YVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKE- 349
V+P P+ C C C L Y +ACA+ + GWRT L C C
Sbjct: 1064 IVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGL--CEHSCPSG 1121
Query: 350 KAFTYNECIACCPASCH---PRASCVDSEIACVDGCYCPNGLI-FEDGGCVAPAECPCEF 405
F YN + C +SC R D E VDGC CP+ + +G CV ++C C
Sbjct: 1122 LVFKYN--VKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYI 1179
Query: 406 HGTLYPPGSVVKEDCNTCTCTSGKWECSTAV 436
+ + PG ++ D N C C G C +
Sbjct: 1180 NDEVMQPGKLIHIDDNKCVCRDGILLCQIPI 1210
Score = 75.5 bits (184), Expect = 7e-13
Identities = 56/207 (27%), Positives = 89/207 (42%), Gaps = 26/207 (12%)
Query: 2174 GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDS---CATT 2230
GLCG +GD +D T + SV GA + F +SW+ + F DS C
Sbjct: 1450 GLCGNNNGDLKDDFTTRYSSVASGALE---FGNSWKTSQECSDTVAQTFPCDSNPYCKAW 1506
Query: 2231 DCSPCLRMVSNRTFSACHRFVPPESFCELWIRDT-------KYVQQPCVALTVYVAMCHK 2283
C ++ + TF CH V P ++ ++ I + KY+ C A+ +Y C
Sbjct: 1507 AVRKC-EILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGF-CTAVAMYAEACSA 1564
Query: 2284 FHVCIEWRRSDYCPFLCSSDSTYQACVTACEP-----PKTCQDGILGPLDPEHCQVLGEG 2338
VC+ WR+ + CP C + C EP KTC+D ++G + L EG
Sbjct: 1565 VGVCVSWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVG----QKFSSLLEG 1620
Query: 2339 CV--CSEGTILHRRHSALCIPEAKCAC 2363
C C + ++ C+ ++C+C
Sbjct: 1621 CYAKCPDSAPYLDENTMKCVSLSECSC 1647
Score = 73.6 bits (179), Expect = 3e-12
Identities = 124/529 (23%), Positives = 190/529 (35%), Gaps = 80/529 (15%)
Query: 1336 CEWRYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCP-TPQVLDEVTQRCVYLEDC--- 1391
C W Y+ C + +TC+D + + +EGC CP + LDE T +CV L +C
Sbjct: 1590 CRWHYEPCGTVTAKTCKD-QLVGQKFSSLLEGCYAKCPDSAPYLDENTMKCVSLSECSCF 1648
Query: 1392 ---VEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTAL 1448
V PA V + G T G S+ P S + T T L+ A +T
Sbjct: 1649 YNDVIPAGGVIEDNCG-RTCYCIAGQLECSETAPTNSTFAVSTTTATTILSTGAAITLVT 1707
Query: 1449 NPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSS 1508
P TA P ++ ++TT GP P + G+T + + I T ++
Sbjct: 1708 GGPSTAASIPAITTSSSETT----------GTTLGPLTEPFTTGITETSVPIISTSGNAG 1757
Query: 1509 LPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLP 1568
+ + G A T V G+ + S R+ PR T AV G GS
Sbjct: 1758 MTGVVSPTVTGASGMAGTTGGVDAATTGAASENTSERA-GTPRVSGATPAV---GGGS-- 1811
Query: 1569 VRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQS 1628
TP + A+ S S G+I+ SP +S A + S++G P+
Sbjct: 1812 ---TPGEAGPGATVSGSTGVSAGSITASPGAS---------ATSSESSKSGTTGPSVGGK 1859
Query: 1629 ASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAP 1688
+ S+ T + + S +T + ++ + G SP P P +P
Sbjct: 1860 TGATSSEATSSEGMSGVTGQSLGSTAGSDSEITAKTSFTG-----SSPPGKLTRPSPGSP 1914
Query: 1689 PRPAQHTT------------------MATRSPALPPETPAAASLSTATDG---------- 1720
+ TT + + ++ T A + + T G
Sbjct: 1915 GHFSGGTTEWGNVATTGAAGENTSGALGSTEGSVEATTSAGSGNTAGTSGTGDTGPGNTA 1974
Query: 1721 LAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAPVA----TPGPKASVITTPLQPQA 1776
++ TP +S +T P S P + + G S T A + TP A
Sbjct: 1975 VSGTPVVSPGAT-PGAPGSSTPGEADIGNTSFGKSGKSGHDSLTVLNPAFLRRTPTVSAA 2033
Query: 1777 TTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSG 1825
+T T SPV T AA A + P GT G G + TSG
Sbjct: 2034 ST----TSSPVSKHTDAASATAVTISGSKPGTPGTPGGATSGGKI-TSG 2077
Score = 49.7 bits (117), Expect = 4e-05
Identities = 91/424 (21%), Positives = 152/424 (35%), Gaps = 59/424 (13%)
Query: 1975 TSTTCVPIAEQDCVRHI-CLEGQLIR-VNQSQHCPQGAAPPRCGILGLAVRVG------- 2025
T + P + +CV C EG L+ + + C A P C G + G
Sbjct: 778 TCSNVAPFQDSECVSGCTCPEGYLLDDIGEKGKCVLKAECP-CESSGTVYQPGEVREGPC 836
Query: 2026 GDRC--------CPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHV 2077
G +C C C RC + S TFDG ++ + D ++V +
Sbjct: 837 GSQCTCQDAKWSCTEALCPGRCKV-EGSSLTTFDGVKYNFPGNCHFLAVHNEDWSISVEL 895
Query: 2078 LDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDR--FNRKVTVDLQPVWPPVSRYGFRIE 2135
C S G CL + + L V +D+ FN TV + Y +I+
Sbjct: 896 RPCPSGQTGT------CLNSVTLL-LNSSVPVDKYVFNSDGTVTNDKIRNQGYYYSDKIQ 948
Query: 2136 --DTGHMYMILTPS---DIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLK 2190
+ Y+ + +QIQ + L V GLCG + A +D
Sbjct: 949 IFNASSSYLQVETYFHVKLQIQIVPVMQLY-VSMPPNQFTDTVGLCGSYNNKAEDDFMSS 1007
Query: 2191 DGSVVGGAEDPAPFLDSWQV-------PSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRT 2243
+ ++ F +SW++ PSS S+ + +F C + + S+
Sbjct: 1008 QNILEKTSQ---AFANSWEMMSCPKGNPSSCISIEKEKFAERHCG-------ILLDSSGP 1057
Query: 2244 FSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCIEWRRSDYCPFL 2299
++CH V P+ + E + T + C L YV C + I R+ C
Sbjct: 1058 LASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHS 1117
Query: 2300 CSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEA 2359
C S ++ V AC D E V +GC C + +++ + C+ ++
Sbjct: 1118 CPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPV--DGCTCPDA--MYQNNEGNCVLKS 1173
Query: 2360 KCAC 2363
+C C
Sbjct: 1174 QCDC 1177
>gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo
sapiens]
Length = 2134
Score = 476 bits (1226), Expect = e-133
Identities = 288/932 (30%), Positives = 447/932 (47%), Gaps = 65/932 (6%)
Query: 275 EQCEALLRPPFDACHAYVS-PLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGR-P 332
+ C ++ F+ C + + C + CQ+ +T C +E +R CA G
Sbjct: 687 QHCNKIIGTYFEKCGKVAALSNDYKMICIDEYCQTRDKTST-CDTYSELSRLCASDGPGT 745
Query: 333 LQGWRTQLRQC--TVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIF 390
+ WR+ T C E+ Y EC PA+C A DSE CV GC CP G +
Sbjct: 746 FESWRSDSDVVCGTQRCPEQHI-YKECGPSNPATCSNVAPFQDSE--CVSGCTCPEGYLL 802
Query: 391 ED----GGCVAPAECPCEFHGTLYPPGSVVKEDCNT-CTCTSGKWECSTAVCPAECSVTG 445
+D G CV AECPCE GT+Y PG V + C + CTC KW C+ A+CP C V G
Sbjct: 803 DDIGEKGKCVLKAECPCESSGTVYQPGEVREGPCGSQCTCQDAKWSCTEALCPGRCKVEG 862
Query: 446 DIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDP 505
TTFDG +Y FP C ++ + ++++++ PC Q G C+ SV+++L+
Sbjct: 863 S-SLTTFDGVKYNFPGNCHFLAVHNED---WSISVELRPCPSGQTGTCLNSVTLLLNSSV 918
Query: 506 RRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRV-LYDREGLRLY 564
+ + + D+ + Y D +I SS +L+V T V++ + ++LY
Sbjct: 919 PVDKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASSSYLQVETYFHVKLQIQIVPVMQLY 978
Query: 565 LQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLD 624
+ + DTVGLCG++N +DDF+S + E T Q F NSW+ +S G+P
Sbjct: 979 VSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMSC----PKGNP-S 1033
Query: 625 PCDVHLQAASYSVQACSVLTGEM--FAPCSAFLSPVPYFEQCRRDACRC--GQPCLCATL 680
C + ++ ++ + C +L A C ++P PY E+C++ C C Q CLC L
Sbjct: 1034 SC-ISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTIL 1092
Query: 681 AHYAHLC-RRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPE-ACGVDGG 738
+Y C + V +R L C SC + + V C +C+ L+ + +C V+
Sbjct: 1093 GNYVKACAEKETYIVGWRTGL--CEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVE-- 1148
Query: 739 DDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCHCKDG 798
D V+GC CP Y + + + CV ++QC C+ PG C C+DG
Sbjct: 1149 -----DVPVDGCTCPDAMYQNNEGN-CVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDG 1202
Query: 799 VMSCDSRAPAAA--CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARG-PCLSGCA 855
++ C C G +V+CSD + RTC + N+ V PC GC
Sbjct: 1203 ILLCQIPIDLTLQNCSGGAEYVDCSD--PKAQRRTNRTCSTR--NIPVFDENLPCKRGCF 1258
Query: 856 CPQGLLRHGDA-CFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCT 914
CP+G++R+ C P +CPC++ G+EY G C+ C C +GS+ CT + C + C
Sbjct: 1259 CPEGMVRNSKGICVFPNDCPCSFGGREYDEGSVTSVGCNECTCIKGSWSCTQNECQTICH 1318
Query: 915 AYGDRHYRTFDGLPFDFVGACKVHLVKST---SDVSFSVIVENVNCYSSGMICRKFISIN 971
YG+ H RTFDG + F G C+ ++ + +F ++ E+V C G+ C + I +
Sbjct: 1319 IYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHENGTFRILTESVPCCEDGLTCSRKIIVA 1378
Query: 972 VGNSLIVFDDDSGNPSPESFLDDKQ--------EVHTWRVGFFTLVHFPQEHITLLWDQR 1023
+ IV D G + + K+ +HT VG + ++ F Q I ++WD+
Sbjct: 1379 FQDQNIVLQD--GKVTAVKSTESKKCELNANAYSIHT--VGLYLILKF-QNGIIVIWDKN 1433
Query: 1024 TTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSW-AAVECPDTLDP 1082
T + V P W G++ GLCGN + ++ T + + EFG+SW + EC DT+
Sbjct: 1434 TRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQ 1493
Query: 1083 RDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCA 1142
C NP + +A ++C IL F CH VD + ++ C+ + C C G FC
Sbjct: 1494 TFPCDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCT 1553
Query: 1143 SVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFN 1174
+V+ YA C GV V WR P LCP CD++N
Sbjct: 1554 AVAMYAEACSAVGVCVSWRKPNLCPVYCDYYN 1585
Score = 211 bits (537), Expect = 8e-54
Identities = 140/455 (30%), Positives = 201/455 (44%), Gaps = 41/455 (9%)
Query: 373 DSEIACVDGCYCPNGLIFEDGG-CVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWE 431
D + C GC+CP G++ G CV P +CPC F G Y GSV CN CTC G W
Sbjct: 1248 DENLPCKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYDEGSVTSVGCNECTCIKGSWS 1307
Query: 432 CSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKS---RSSGTFTVTLQNAPCGLN 488
C+ C C + G+ H TFDG+ Y+F CQY + +GTF + ++ PC
Sbjct: 1308 CTQNECQTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHENGTFRILTESVPCC-- 1365
Query: 489 QDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIP-PYTDDAFEIRRLSSVFLRVR 547
+DG ++ QD Q + Q G V + +A+ I + ++L ++
Sbjct: 1366 EDGLTCSRKIIVAFQD---QNIVLQDGKVTAVKSTESKKCELNANAYSIHTVG-LYLILK 1421
Query: 548 TNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNS 607
G+ V++D+ RL + +D W GLCG NG+ +DDF + S FGNS
Sbjct: 1422 FQNGIIVIWDKN-TRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNS 1480
Query: 608 WKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRD 667
WKT CS V+ + PCD + +++V+ C +L F C + P Y + C +
Sbjct: 1481 WKTSQECSDTVAQT--FPCDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEE 1538
Query: 668 ACRCGQPC----LCATLAHYAHLCRRHGLPVDFRARLPACALSC-------EASKEYSPC 716
AC C C +A YA C G+ V +R + C + C E Y PC
Sbjct: 1539 ACACDMEGKYLGFCTAVAMYAEACSAVGVCVSWR-KPNLCPVYCDYYNAPGECRWHYEPC 1597
Query: 717 VAPCGRTCQDLASPEACGVDGGDDLSRDECVEGC--ACPPDT-YLDTQADLCVPRNQCSC 773
+TC+D G S +EGC CP YLD CV ++CSC
Sbjct: 1598 GTVTAKTCKDQLV--------GQKFS--SLLEGCYAKCPDSAPYLDENTMKCVSLSECSC 1647
Query: 774 HFQGVDYPPGDSDIPSLGH-CHCKDGVMSCDSRAP 807
+ V P G + G C+C G + C AP
Sbjct: 1648 FYNDV-IPAGGVIEDNCGRTCYCIAGQLECSETAP 1681
Score = 132 bits (333), Expect = 4e-30
Identities = 107/380 (28%), Positives = 167/380 (43%), Gaps = 34/380 (8%)
Query: 74 ERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRH-EPEGQSFSIQVHNDPQCGSSPYT 132
E +IC +G+ HV TFDG Y G Y+ + + E +F I + P C T
Sbjct: 1312 ECQTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHENGTFRILTESVPCCEDG-LT 1370
Query: 133 CSRAVSLFFVGEQEIHLAKEVTH----GGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTL 188
CSR + + F + + +VT + +L + + + Y+I++ Q+ +
Sbjct: 1371 CSRKIIVAFQDQNIVLQDGKVTAVKSTESKKCELN--ANAYSIHTVGLYLILKFQNGIIV 1428
Query: 189 AWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQ 248
WD + + + + P G GLCGNNN D KDD T + +EF +SW+ +Q
Sbjct: 1429 IWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWK---TSQ 1485
Query: 249 PPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSD--LC 306
T + PC NP +CE L F CH V P + C + C
Sbjct: 1486 ECSDTVAQ--TFPC-DSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACAC 1542
Query: 307 QSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCK------EKAFTYNECIAC 360
G +C A+A YA AC+ G WR + C V+C E + Y C
Sbjct: 1543 DMEGKYLGFCTAVAMYAEACSAVG-VCVSWR-KPNLCPVYCDYYNAPGECRWHYEPCGTV 1600
Query: 361 CPASCHPRASCVDSEI-ACVDGCY--CPNGLIFEDGG---CVAPAECPCEFHGTLYPPGS 414
+C + V + + ++GCY CP+ + D CV+ +EC C F+ + P G
Sbjct: 1601 TAKTC--KDQLVGQKFSSLLEGCYAKCPDSAPYLDENTMKCVSLSECSC-FYNDVIPAGG 1657
Query: 415 VVKEDC-NTCTCTSGKWECS 433
V++++C TC C +G+ ECS
Sbjct: 1658 VIEDNCGRTCYCIAGQLECS 1677
Score = 111 bits (277), Expect = 1e-23
Identities = 114/451 (25%), Positives = 164/451 (36%), Gaps = 83/451 (18%)
Query: 33 CAPSYLFSCFNG-GECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRA--------W- 82
C YL G+CV A C C VY G R+ C + W
Sbjct: 796 CPEGYLLDDIGEKGKCVLKAECPCESSGT-------VYQPGEVREGPCGSQCTCQDAKWS 848
Query: 83 -------GQHHVE-----TFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSP 130
G+ VE TFDG+ Y G + V + +SI V P
Sbjct: 849 CTEALCPGRCKVEGSSLTTFDGVKYNFPGNCHFLAV-----HNEDWSISVELRPCPSGQT 903
Query: 131 YTCSRAVSLFF-----VGEQEIHLAKEVTHGGMRVQ-------LPHVMGSARLQQLAGYV 178
TC +V+L V + + VT+ +R Q + S+ Q+ Y
Sbjct: 904 GTCLNSVTLLLNSSVPVDKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASSSYLQVETYF 963
Query: 179 IVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFV 238
V+ Q +Y+ M P T GLCG+ N +DD ++S L F
Sbjct: 964 HVKLQIQIVPVMQ----LYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFA 1019
Query: 239 HSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQ------CEALL--RPPFDACHA 290
+SW+ + C + NP + + ++ C LL P +CH
Sbjct: 1020 NSWEMMS----------------CPKGNPSSCISIEKEKFAERHCGILLDSSGPLASCHP 1063
Query: 291 YVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKE- 349
V+P P+ C C C L Y +ACA+ + GWRT L C C
Sbjct: 1064 IVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGL--CEHSCPSG 1121
Query: 350 KAFTYNECIACCPASCH---PRASCVDSEIACVDGCYCPNGLI-FEDGGCVAPAECPCEF 405
F YN + C +SC R D E VDGC CP+ + +G CV ++C C
Sbjct: 1122 LVFKYN--VKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYI 1179
Query: 406 HGTLYPPGSVVKEDCNTCTCTSGKWECSTAV 436
+ + PG ++ D N C C G C +
Sbjct: 1180 NDEVMQPGKLIHIDDNKCVCRDGILLCQIPI 1210
Score = 75.5 bits (184), Expect = 7e-13
Identities = 56/207 (27%), Positives = 89/207 (42%), Gaps = 26/207 (12%)
Query: 2174 GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDS---CATT 2230
GLCG +GD +D T + SV GA + F +SW+ + F DS C
Sbjct: 1450 GLCGNNNGDLKDDFTTRYSSVASGALE---FGNSWKTSQECSDTVAQTFPCDSNPYCKAW 1506
Query: 2231 DCSPCLRMVSNRTFSACHRFVPPESFCELWIRDT-------KYVQQPCVALTVYVAMCHK 2283
C ++ + TF CH V P ++ ++ I + KY+ C A+ +Y C
Sbjct: 1507 AVRKC-EILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGF-CTAVAMYAEACSA 1564
Query: 2284 FHVCIEWRRSDYCPFLCSSDSTYQACVTACEP-----PKTCQDGILGPLDPEHCQVLGEG 2338
VC+ WR+ + CP C + C EP KTC+D ++G + L EG
Sbjct: 1565 VGVCVSWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVG----QKFSSLLEG 1620
Query: 2339 CV--CSEGTILHRRHSALCIPEAKCAC 2363
C C + ++ C+ ++C+C
Sbjct: 1621 CYAKCPDSAPYLDENTMKCVSLSECSC 1647
Score = 73.6 bits (179), Expect = 3e-12
Identities = 128/545 (23%), Positives = 197/545 (36%), Gaps = 82/545 (15%)
Query: 1336 CEWRYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCP-TPQVLDEVTQRCVYLEDC--- 1391
C W Y+ C + +TC+D + + +EGC CP + LDE T +CV L +C
Sbjct: 1590 CRWHYEPCGTVTAKTCKD-QLVGQKFSSLLEGCYAKCPDSAPYLDENTMKCVSLSECSCF 1648
Query: 1392 ---VEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTAL 1448
V PA V + G T G S+ P S + T T L+ A +T
Sbjct: 1649 YNDVIPAGGVIEDNCG-RTCYCIAGQLECSETAPTNSTFAVSTTTATTILSTGAAITLVT 1707
Query: 1449 NPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSS 1508
P TA P ++ ++TT GP P + G+T + + I T ++
Sbjct: 1708 GGPSTAASIPAITTSSSETT----------GTTLGPLTEPFTTGITETSVPIISTSGNAG 1757
Query: 1509 LPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLP 1568
+ + G A T V G+ + S R+ PR T AV G GS
Sbjct: 1758 MTGVVSPTVTGASGMAGTTGGVDAATTGAASENTSERA-GTPRVSGETPAV---GGGS-- 1811
Query: 1569 VRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQS 1628
TP + A+ S S G+I+ SP +S A + S++G P+
Sbjct: 1812 ---TPGEAGPGATVSGSTGVSAGSITASPGAS---------ATSSESSKSGTTGPSVGGK 1859
Query: 1629 ASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAP 1688
+ S+ T + + S +T + ++ + G SP P P +P
Sbjct: 1860 TGATSSEATSSEGMSGVTGQSLGSTAGSDSEITAKTSFTG-----SSPPGKLTRPSPGSP 1914
Query: 1689 PRPAQHTT------------------MATRSPALPPETPAAASLSTATDG---------- 1720
+ TT + + ++ T A + + T G
Sbjct: 1915 GHFSGGTTEWGNVATTGAAGENTSGALGSTEGSVEATTSAGSGNTAGTSGTGDTGPGNTA 1974
Query: 1721 LAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAPVA----TPGPKASVITTPLQPQA 1776
++ TP +S +T P S P + + G S T A + TP A
Sbjct: 1975 VSGTPVVSPGAT-PGAPGSSTPGEADIGNTSFGKSGKSGHDSLTVLNPAFLRRTPTVSAA 2033
Query: 1777 TTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASM 1836
+T T SPV T AA A + P GT G G + TSG + GT++
Sbjct: 2034 ST----TSSPVSKHTDAASATAVTISGSKPGTPGTPGGATSGGKI-TSGW--SSSGTSTG 2086
Query: 1837 VSVVP 1841
S P
Sbjct: 2087 ASNTP 2091
Score = 49.7 bits (117), Expect = 4e-05
Identities = 91/424 (21%), Positives = 152/424 (35%), Gaps = 59/424 (13%)
Query: 1975 TSTTCVPIAEQDCVRHI-CLEGQLIR-VNQSQHCPQGAAPPRCGILGLAVRVG------- 2025
T + P + +CV C EG L+ + + C A P C G + G
Sbjct: 778 TCSNVAPFQDSECVSGCTCPEGYLLDDIGEKGKCVLKAECP-CESSGTVYQPGEVREGPC 836
Query: 2026 GDRC--------CPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHV 2077
G +C C C RC + S TFDG ++ + D ++V +
Sbjct: 837 GSQCTCQDAKWSCTEALCPGRCKV-EGSSLTTFDGVKYNFPGNCHFLAVHNEDWSISVEL 895
Query: 2078 LDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDR--FNRKVTVDLQPVWPPVSRYGFRIE 2135
C S G CL + + L V +D+ FN TV + Y +I+
Sbjct: 896 RPCPSGQTGT------CLNSVTLL-LNSSVPVDKYVFNSDGTVTNDKIRNQGYYYSDKIQ 948
Query: 2136 --DTGHMYMILTPS---DIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLK 2190
+ Y+ + +QIQ + L V GLCG + A +D
Sbjct: 949 IFNASSSYLQVETYFHVKLQIQIVPVMQLY-VSMPPNQFTDTVGLCGSYNNKAEDDFMSS 1007
Query: 2191 DGSVVGGAEDPAPFLDSWQV-------PSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRT 2243
+ ++ F +SW++ PSS S+ + +F C + + S+
Sbjct: 1008 QNILEKTSQ---AFANSWEMMSCPKGNPSSCISIEKEKFAERHCG-------ILLDSSGP 1057
Query: 2244 FSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCIEWRRSDYCPFL 2299
++CH V P+ + E + T + C L YV C + I R+ C
Sbjct: 1058 LASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHS 1117
Query: 2300 CSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEA 2359
C S ++ V AC D E V +GC C + +++ + C+ ++
Sbjct: 1118 CPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPV--DGCTCPDA--MYQNNEGNCVLKS 1173
Query: 2360 KCAC 2363
+C C
Sbjct: 1174 QCDC 1177
>gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]
Length = 2639
Score = 430 bits (1105), Expect = e-119
Identities = 243/698 (34%), Positives = 377/698 (54%), Gaps = 39/698 (5%)
Query: 498 SVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYD 557
+V+L D ++ V + ++ +L ++ ++ P+ +F + R SS + V +GVR+
Sbjct: 347 TVVLLADKKKNVVVFKSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQ 406
Query: 558 REG-LRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSP 616
++L++ +DQ GLCG FNG DDF + G+ E+T F N+WK S+C
Sbjct: 407 LAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHD 466
Query: 617 LVSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDACRC--G 672
+ DPC +++++A+Y+ CS+L T F C + + P Y+++C+ D C C
Sbjct: 467 KLDWLD-DPCSLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNN 525
Query: 673 QPCLCATLAHYAHLCRRHGLPVDFRARLPACAL---SCEASKEYSPCVAPCGRTCQDLAS 729
+ CLCA L+ YA C G+ + + R C SC S+ + + C +TC+ L+
Sbjct: 526 EDCLCAALSSYARACTAKGVML-WGWREHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSE 584
Query: 730 PEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPS 789
++ ++G V+GC CP T+LD + CVP +CSC+ +G+ GD +
Sbjct: 585 ADSHCLEGFAP------VDGCGCPDHTFLDEKGR-CVPLAKCSCYHRGLYLEAGDVVVRQ 637
Query: 790 LGHCHCKDGVMSCDS-RAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARG 848
C C+DG + C R +C A ++ ++CS+L T L S+ R Q L
Sbjct: 638 EERCVCRDGRLHCRQIRLIGQSCTAPKIHMDCSNL-TALATSKPRALSCQTLAAGYY-HT 695
Query: 849 PCLSGCACPQGLLRHG-DACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLH 907
C+SGC CP GL+ G C + +ECPC Y G ++ C+TC C+RG + CT
Sbjct: 696 ECVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQA 755
Query: 908 PCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVK-----STSDVSFSVIVENVNCYSSGM 962
C TC+ YG HY TFDG +DF G C V+ ++S SFS+I ENV C ++G+
Sbjct: 756 VCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGV 815
Query: 963 ICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVH-----TWRVGFFTLVHFPQEHIT 1017
C K I I +G + + +D + + E H T VG + +V I
Sbjct: 816 TCSKAIKIFMGRTELKLEDK------HRVVIQRDEGHHVAYTTREVGQYLVVE-SSTGII 868
Query: 1018 LLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWA-AVEC 1076
++WD+RTTV ++ P ++G + GLCGNFD ++ N+ T +++ +++ +FG+SW A C
Sbjct: 869 VIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTC 928
Query: 1077 PDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGD 1136
PD + C LNP R +A+K+CSIL S VF ICH VD FY C+ D+C C GGD
Sbjct: 929 PDVSTNPEPCSLNPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGD 988
Query: 1137 CECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFN 1174
CECFC++V++YA +C + G V WRTP LCP CD++N
Sbjct: 989 CECFCSAVASYAQECTKEGACVFWRTPDLCPIFCDYYN 1026
Score = 239 bits (610), Expect = 3e-62
Identities = 318/1356 (23%), Positives = 477/1356 (35%), Gaps = 232/1356 (17%)
Query: 1380 EVTQRCVYLEDCVEPAVWVPTEALGNETLPP----SQGLPTPSDEEPQLSQESP--RTPT 1433
E+ +C +CV + T N T P + PTP+ Q + +P T T
Sbjct: 1288 EINVQCC---ECVTQPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTT 1344
Query: 1434 HRPALTPAAPLTTALNP-PVTATEEPVVSPGPTQTTLQQPLELTASQLPAGP---TESPA 1489
P TP T P T T P +P TQT P+ T + P T++P
Sbjct: 1345 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 1404
Query: 1490 SKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPA 1549
S +T + P TP P QTPT TT +T +P T + P
Sbjct: 1405 STPITTTTTVTP-TPT----PTGTQTPT---------TTPITTTTTVTPTPTPTGTQAPT 1450
Query: 1550 PRFPLMTKAVTVRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTP 1609
P T VT P P+ T +P++ P+ + ++ +PT +G+ TP
Sbjct: 1451 PTAITTTSTVT-----------PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ----TP 1495
Query: 1610 AVTKVISRTGV-PQPTQAQSASSPSTPLTVAGTAAE-------QVPV-SPLATRSLEIVL 1660
T + + T V P PT + + STP+T T Q P +P++T +
Sbjct: 1496 TPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPT 1555
Query: 1661 STEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATD 1719
T G + + P+ + + P P P+ P + T + P TP T+T
Sbjct: 1556 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-VLITTTTTMTPTPTP------TSTK 1608
Query: 1720 GLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAPVATP-----GPKASVITTPLQP 1774
TP + + + +G T +P++ T P TP GP T P+
Sbjct: 1609 STTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAE 1668
Query: 1775 QATTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTA 1834
T+ P PP P + + L +T S + P E T+
Sbjct: 1669 LTTSNP-------------------PPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
Query: 1835 SMVSVVPRKSTTGKVAILSKQVSLPTSMYGSAEGGPTE-LTPATSHPLTPLVAEPEGAQA 1893
+ P TT +S P S S G PT T +S TP + A
Sbjct: 1710 TAPPSTPTAPTTTSGG---HTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSA 1766
Query: 1894 GTALPVPTSYALSRVSARTAPQDSMLVLLPQLAEAH---------GTSAGPHLAAEPVDE 1944
T P P S + P S +++ L + + GT
Sbjct: 1767 WTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLS 1826
Query: 1945 ATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVPIAEQ------------------- 1985
T E S P+ T +ST P
Sbjct: 1827 CTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECPDFDPPRQENETWW 1886
Query: 1986 --DCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGG-DRCCPLWECACRCSIF 2042
DC C + + + + P P C VRV D CC WEC C C+ +
Sbjct: 1887 LCDCFMATCKYNNTVEIVKVECEPPPM--PTCSNGLQPVRVEDPDGCCWHWECDCYCTGW 1944
Query: 2043 PDLSFVTFDGSHVALFKEAIYILSQ--SPDEMLTVHVLDCKSANLGHLNWPP----FCLV 2096
D +VTFDG + + Y+L + SP +D + + + P C
Sbjct: 1945 GDPHYVTFDGLYYSYQGNCTYVLVEEISPS-------VDNFGVYIDNYHCDPNDKVSCPR 1997
Query: 2097 MLNMTHLAHQVTIDRFNR-----KVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQI 2151
L + H +V I + +V V+ Q V P +YG + +G Y++ P +
Sbjct: 1998 TLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVL 2057
Query: 2152 QWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVP 2211
+ + G CG C ++D L G +V E A D W V
Sbjct: 2058 VSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAA---DQWLVN 2114
Query: 2212 ---------SSLTSVGQTRFRPDSCATT---DC--SPCLRMVSNRTFSACHRFVPPESFC 2257
SS T+ P TT DC SP +++ + F+ CH VPP+ +
Sbjct: 2115 DPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYY 2174
Query: 2258 ELWIRDTKYV---QQPCVALTVYVAMCHKFHVCIEWRRSDY--CPFLCSSDSTYQACVTA 2312
+ + D+ ++ C +L Y A+C + ++C++WR + C C S YQAC A
Sbjct: 2175 DACVFDSCFMPGSSLECASLQAYAALCAQQNICLDWRNHTHGACLVECPSHREYQACGPA 2234
Query: 2313 CEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRA 2372
EP TC+ ++ VL EGC C EGT+ + +C+ C C VPR
Sbjct: 2235 EEP--TCKSSS----SQQNNTVLVEGCFCPEGTMNYAPGFDVCVKT--CGCVGPDNVPRE 2286
Query: 2373 LGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGE-VALLLPTKDPCCLGTV 2431
GE + C + I+ C C+ G +A + D CC TV
Sbjct: 2287 FGEHFEFDCKNCVC--LEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTCCNITV 2344
Query: 2432 CVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCECDPDLC---EAELVPSCRQDQIL 2488
C CN +LC+ C G + + CCP Y CE +C AE P
Sbjct: 2345 CKCNTSLCKEKPSVCPLGFEVKSKMVPGRCCPFYWCE-SKGVCVHGNAEYQPG------- 2396
Query: 2489 ITGRLGDSCCTSYFCACGDCPDSIPECQEGEALTVHRNTTELCCPLYQCVCENFRCPQVQ 2548
Y C DC C + V NT L C + C
Sbjct: 2397 ---------SPVYSSKCQDC-----VCTD----KVDNNTL-----LNVIACTHVPC-NTS 2432
Query: 2549 CGLGTALVEVWSPDRCCPYKSCE---C---------------DCDTIPVPRCHLWEKSQL 2590
C G L+E +P CC K CE C D + P C + ++
Sbjct: 2433 CSPGFELME--APGECC--KKCEQTHCIIKRPDNQHVILKPGDFKSDPKNNCTFFSCVKI 2488
Query: 2591 DEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPG 2626
+ + SV N+ C ++ A +C+ + M G
Sbjct: 2489 HNQLISSVSNIT-CPNFD---ASICIPGSITFMPNG 2520
Score = 231 bits (589), Expect = 8e-60
Identities = 190/769 (24%), Positives = 312/769 (40%), Gaps = 164/769 (21%)
Query: 158 MRVQLPHVMGSARLQQLAGYVIVRHQSA---FTLAWDGASAVYIKMSPELLGWTHGLCGN 214
++V LPHV S + + + Y I+ + + +++ + G GLCGN
Sbjct: 372 LQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGLCGN 431
Query: 215 NNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVY 274
N DD T+SG + F ++W+ Q+ PC N +
Sbjct: 432 FNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKLDWLDD----PC-SLNIESANYAE 486
Query: 275 EQCEALLRP--PFDACHAYVSPLPF-------TASCTSD---LCQSMGD---------VA 313
C L + PF CH+ V P + T +C ++ LC ++ V
Sbjct: 487 HWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGVM 546
Query: 314 TW------------------------------CRALAEYARACAQAGRPLQGW------- 336
W CR+L+E C + P+ G
Sbjct: 547 LWGWREHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGCPDHTF 606
Query: 337 ---------------------------------RTQLRQCTVHCKEKAFTYNECIA---- 359
R R +HC++ C A
Sbjct: 607 LDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEERCVCRDGRLHCRQIRLIGQSCTAPKIH 666
Query: 360 ------CCPASCHPRASCVDSEIA------CVDGCYCPNGLIFED-GGCVAPAECPCEFH 406
A+ PRA + A CV GC CP+GL+ + GGCV ECPC +
Sbjct: 667 MDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDGLMDDGRGGCVVEKECPCVHN 726
Query: 407 GTLYPPGSVVKEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYI 466
LY G+ +K DCNTCTC G+W C+ AVC CS+ G H+ TFDG+ Y F C Y+
Sbjct: 727 NDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYV 786
Query: 467 -----LAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFD 521
++ S G+F++ +N PCG C +++ + + + ++ L D
Sbjct: 787 AVQDYCGQNSSLGSFSIITENVPCG-TTGVTCSKAIKIFMGRT-----------ELKLED 834
Query: 522 QYKIIPPYTDD---AFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGL 578
+++++ + A+ R + +L V ++ G+ V++D+ +++++ + GL
Sbjct: 835 KHRVVIQRDEGHHVAYTTREVGQ-YLVVESSTGIIVIWDKR-TTVFIKLAPSYKGTVCGL 892
Query: 579 CGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQ 638
CG F+ + +DF + + S+ FGNSWK C P VS +P +PC ++ S++ +
Sbjct: 893 CGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTC-PDVSTNP-EPCSLNPHRRSWAEK 950
Query: 639 ACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQ----PCLCATLAHYAHLCRRHGLPV 694
CS+L +F+ C + + P P++E C D+C C C C+ +A YA C + G V
Sbjct: 951 QCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACV 1010
Query: 695 DFRARLPACALSC-------EASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECV 747
+R C + C E Y PC TC+ + G+ +S +
Sbjct: 1011 FWRTP-DLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTIN-----GIHSNISVS---YL 1061
Query: 748 EGC--ACPPDTYL-DTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHC 793
EGC CP D + + CV ++C C+ + YPPG S +P+ C
Sbjct: 1062 EGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGAS-VPTEETC 1109
Score = 157 bits (398), Expect = 1e-37
Identities = 125/396 (31%), Positives = 180/396 (45%), Gaps = 40/396 (10%)
Query: 79 CRAWGQHHVETFDGLYYYLSGKGSYTLV----GRHEPEGQSFSIQVHNDPQCGSSPYTCS 134
C +G H TFDG YY G SY V G++ G SFSI N P CG++ TCS
Sbjct: 761 CSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLG-SFSIITENVP-CGTTGVTCS 818
Query: 135 RAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGAS 194
+A+ +F +G E+ L + R + HV + R ++ Y++V + + WD +
Sbjct: 819 KAIKIF-MGRTELKLEDKHRVVIQRDEGHHVAYTTR--EVGQYLVVESSTGIIVIWDKRT 875
Query: 195 AVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTT 254
V+IK++P G GLCGN + +D T + ++F +SW+E P P
Sbjct: 876 TVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKE----APTCPDV 931
Query: 255 SSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSD--LCQSMGDV 312
S+ P P L NP +QC L F CH+ V P PF +C D C + GD
Sbjct: 932 STNPEPCSL--NPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDC 989
Query: 313 ATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHC------KEKAFTYNECIACCPASCH 366
+C A+A YA+ C + G + WRT C + C E + Y C +C
Sbjct: 990 ECFCSAVASYAQECTKEGACV-FWRTP-DLCPIFCDYYNPPHECEWHYEPCGNRSFETCR 1047
Query: 367 P-RASCVDSEIACVDGCY--CPNGL-IFEDG--GCVAPAECPCEFHGTLYPPGSVV--KE 418
+ ++ ++GCY CP I+E+ CV +C C T YPPG+ V +E
Sbjct: 1048 TINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGASVPTEE 1107
Query: 419 DCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDG 454
C +C CT+ S VC E G I T DG
Sbjct: 1108 TCKSCVCTNS----SQVVCRPE---EGKILNQTQDG 1136
Score = 119 bits (297), Expect = 6e-26
Identities = 139/580 (23%), Positives = 226/580 (38%), Gaps = 108/580 (18%)
Query: 403 CEFHGTLYPPGSVVKEDCNTC---TCTSG--------------KWECSTAVCPAECSVTG 445
C+++ T+ +VK +C TC++G WEC C+ G
Sbjct: 1895 CKYNNTV----EIVKVECEPPPMPTCSNGLQPVRVEDPDGCCWHWECD-----CYCTGWG 1945
Query: 446 DIHFTTFDGRRYTFPATCQYILAK--SRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQ 503
D H+ TFDG Y++ C Y+L + S S F V + N C N +C +++ ++ H+
Sbjct: 1946 DPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSCPRTL-IVRHE 2004
Query: 504 DPR---RQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREG 560
+ V + + ++ + PY E+ + ++ +GV V Y+ G
Sbjct: 2005 TQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVLVSYN--G 2062
Query: 561 LRLYLQVD-QRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLV- 618
L +++ R+ +T G CGT T DD + P G S + + W P
Sbjct: 2063 LSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCP 2122
Query: 619 -SGSPLDPCDVHLQAASYSV--------QACSVLTGEMFAPCSAFLSPVPYFEQCRRDAC 669
S S V + + C ++ +FA C A + P Y++ C D+C
Sbjct: 2123 HSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSC 2182
Query: 670 -RCGQPCLCATLAHYAHLCRRHGLPVDFRARL-PACALSCEASKEYSPCVAPCGRTCQDL 727
G CA+L YA LC + + +D+R AC + C + +EY C TC+
Sbjct: 2183 FMPGSSLECASLQAYAALCAQQNICLDWRNHTHGACLVECPSHREYQACGPAEEPTCKSS 2242
Query: 728 ASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQA-DLCVPRNQCSCHFQGVDYPP---G 783
+S + + VEGC CP T D+CV C C G D P G
Sbjct: 2243 SSQQ----------NNTVLVEGCFCPEGTMNYAPGFDVCV--KTCGC--VGPDNVPREFG 2288
Query: 784 DSDIPSLGHCHCKDG--VMSCD----SRAPAAACPAGQVF----VNCSDLHTDLELSRER 833
+ +C C +G + C S+ P C + VN +D ++ + +
Sbjct: 2289 EHFEFDCKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTCCNITVCKCN 2348
Query: 834 T--CEQQ--LLNLSVSARGPCLSGCACP------QGLLRHGDACFLPEECPCTWKGKEYF 883
T C+++ + L + + G CP +G+ HG+A EY
Sbjct: 2349 TSLCKEKPSVCPLGFEVKSKMVPGRCCPFYWCESKGVCVHGNA--------------EYQ 2394
Query: 884 PGDQV-MSPCHTCVCQ--------RGSFQCTLHPCASTCT 914
PG V S C CVC CT PC ++C+
Sbjct: 2395 PGSPVYSSKCQDCVCTDKVDNNTLLNVIACTHVPCNTSCS 2434
Score = 115 bits (289), Expect = 5e-25
Identities = 109/399 (27%), Positives = 155/399 (38%), Gaps = 49/399 (12%)
Query: 74 ERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTC 133
E D C WG H TFDGLYY G +Y LV P +F + + N + +C
Sbjct: 1936 ECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSC 1995
Query: 134 SRAVSLFFVGEQEIHLAKEVTHGGMRVQ---------LPH-VMGSARLQQLAGYVIVRHQ 183
R +L E + L K V M+VQ LP+ G Q YV+ +
Sbjct: 1996 PR--TLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPE 2053
Query: 184 SAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQE 243
++++G S T G CG DD + SG++ + W
Sbjct: 2054 LGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLV 2113
Query: 244 QAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQ------CEALLRPPFDACHAYVSPLPF 297
P++P P +SS + P + G ++ C+ + F CHA V P +
Sbjct: 2114 NDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHY 2173
Query: 298 TASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLR-QCTVHCKEKAFTYNE 356
+C D C G + C +L YA CAQ L WR C V C ++ E
Sbjct: 2174 YDACVFDSCFMPGS-SLECASLQAYAALCAQQNICLD-WRNHTHGACLVECP----SHRE 2227
Query: 357 CIACCPA---SCHPRASCVDSEIACVDGCYCPNG---------LIFEDGGCVAPAECPCE 404
AC PA +C +S ++ + V+GC+CP G + + GCV P P E
Sbjct: 2228 YQACGPAEEPTCKSSSSQQNNTV-LVEGCFCPEGTMNYAPGFDVCVKTCGCVGPDNVPRE 2286
Query: 405 FHGTLYPPGSVVKEDCNTCTCTSGKWECSTAVC-PAECS 442
F G + DC C C G S +C P CS
Sbjct: 2287 F-------GEHFEFDCKNCVCLEGG---SGIICQPKRCS 2315
Score = 109 bits (273), Expect = 3e-23
Identities = 91/329 (27%), Positives = 145/329 (44%), Gaps = 32/329 (9%)
Query: 441 CSVTGDIHFTTFDGRRYTFPATCQYILAKS--RSSGTFTVTLQNAPCGLNQDGACVQSVS 498
CS G+ H+ TFDG + FP C Y A S F V L+ P G + A V+S+
Sbjct: 37 CSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGP-GQAEAPAGVESIL 95
Query: 499 VILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDR 558
+ + D T+ + + + + P+ I + S + +V + G+ ++++R
Sbjct: 96 LTIKDD-----TIYLTRHLAVLNGAVVSTPHYSPGLLIEK-SDAYTKVYSRAGLTLMWNR 149
Query: 559 EGLRLYLQVDQRWVEDTVGLCGTFNG-NTQDDFLSPVGVPESTPQLFGNSWKTLSACSPL 617
E L L++D ++ T GLCG +NG + +FLS GV S P FGN K +
Sbjct: 150 ED-ALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSD-GVLFS-PLEFGNMQKINQ--PDV 204
Query: 618 VSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRC--GQPC 675
V P + + + + +LT E FA C + PY C++D CRC G C
Sbjct: 205 VCEDPEEEV-APASCSEHRAECERLLTAEAFADCQDLVPLEPYLRACQQDRCRCPGGDTC 263
Query: 676 LCATLAHYAHLC-RRHGLPVDFR----ARLPACALSCEASKEYSPCVAPCGRTCQDLASP 730
+C+T+A ++ C G P ++R A P + +C + Y +PC TC L
Sbjct: 264 VCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTCSHLEVS 323
Query: 731 EACGVDGGDDLSRDECVEGCACPPDTYLD 759
C + ++GC CP D
Sbjct: 324 SLC---------EEHRMDGCFCPEGAQAD 343
Score = 102 bits (255), Expect = 4e-21
Identities = 154/720 (21%), Positives = 244/720 (33%), Gaps = 105/720 (14%)
Query: 1336 CEWRYDACASPCFQTCRDPRAA-SCRDVPRVEGCVPVCPTPQ-VLDEVTQRCVYLEDC-- 1391
CEW Y+ C + F+TCR S V +EGC P CP + + +E ++CV + C
Sbjct: 1031 CEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGC 1090
Query: 1392 ------VEPAVWVPTEALGNETLPPSQGLPTPSDEEPQ-LSQESPRTPTHRPALTPAAPL 1444
P VPTE + + EE + L+Q + P +
Sbjct: 1091 YVEDTHYPPGASVPTEETCKSCVCTNSSQVVCRPEEGKILNQTQDGAFCYWEICGPNGTV 1150
Query: 1445 TTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTP 1504
N T ++ T T P T + PT S + TP
Sbjct: 1151 EKHFNICSITTRPSTLTTFTTITLPTTPTTFTTTTTTTTPTSS----------TVLSTTP 1200
Query: 1505 ESSSL---PVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFP-------- 1553
+ L + P+ G G ET G+P + RS P
Sbjct: 1201 KLCCLWSDWINEDHPSSGSDDGDRETFDGV---CGAPE-DIECRSVKDPHLSLEQLGQKV 1256
Query: 1554 ---------LMTKAVTVRGHGSLPV-----------------RTTPPQPSLTASPSSRPV 1587
L+ K + G +P+ + T + T +P+ P+
Sbjct: 1257 QLVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPTPI 1316
Query: 1588 ASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGT------ 1641
+ ++ +PT + + TP T + T P PT + + +TP+T T
Sbjct: 1317 TTTTTVTPTPTPTSTQSTTPTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 1373
Query: 1642 -AAEQVP-VSPLATRSLEIVLSTEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQHTTMA 1698
Q P +P+ T + T G + S P+ + + P P P+ P T +
Sbjct: 1374 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTT-TPIT 1432
Query: 1699 TRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAP- 1757
T + P TP T T T + + P+ +G T+ P+ T P
Sbjct: 1433 TTTTVTPTPTP------TGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPT 1486
Query: 1758 -----VATPGPKASVITTPLQP--------QATTLPAQTLSPVLPFTPAAMTQAHPPTHI 1804
TP P A TT + P T+ P T + V P TQ PT I
Sbjct: 1487 PTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPI 1546
Query: 1805 APPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSL-PTSMY 1863
+ T G PT+ P+ T + P + T +++ ++ PT
Sbjct: 1547 STTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTP 1604
Query: 1864 GSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDS--MLVL 1921
S + T +TP T+ P G Q T +P+ T+ ++ T
Sbjct: 1605 TSTKS--TTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTS 1662
Query: 1922 LPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 1981
+AE ++ P + +T+ P S LS L A+ T+ A ST P
Sbjct: 1663 TAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLST---LPPAIEMTSTAPPSTPTAP 1719
Score = 91.3 bits (225), Expect = 1e-17
Identities = 78/317 (24%), Positives = 124/317 (39%), Gaps = 18/317 (5%)
Query: 77 SICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRA 136
++C WG H +TFDG + G Y + F++ + P +P
Sbjct: 35 NVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQAEAPAGVESI 94
Query: 137 VSLFFVGEQEIHLAKEVTH-GGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASA 195
L + + I+L + + G V PH +++ Y V ++ TL W+ A
Sbjct: 95 --LLTIKDDTIYLTRHLAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLTLMWNREDA 152
Query: 196 VYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTS 255
+ +++ + T GLCG+ N S G L + EF + Q NQP
Sbjct: 153 LMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPL-EFGNM---QKINQP-----D 203
Query: 256 SLPRPPCLQQNPGTMQGVYEQCEALLRPP-FDACHAYVSPLPFTASCTSDLCQSMGDVAT 314
+ P + P + +CE LL F C V P+ +C D C+ G
Sbjct: 204 VVCEDPEEEVAPASCSEHRAECERLLTAEAFADCQDLVPLEPYLRACQQDRCRCPGGDTC 263
Query: 315 WCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKA---FTYNECIACCPASC-HPRAS 370
C +AE++R C+ AG WRT + + Y E + C +C H S
Sbjct: 264 VCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTCSHLEVS 323
Query: 371 CVDSEIACVDGCYCPNG 387
+ E +DGC+CP G
Sbjct: 324 SLCEEHR-MDGCFCPEG 339
Score = 75.5 bits (184), Expect = 7e-13
Identities = 70/313 (22%), Positives = 118/313 (37%), Gaps = 46/313 (14%)
Query: 904 CTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVK--STSDVSFSVIVENVNCYSSG 961
C C CT +GD HY TFDGL + + G C LV+ S S +F V ++N +C +
Sbjct: 1932 CWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPND 1991
Query: 962 MI-CRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEV---------HTWRVGFFTLVHF 1011
+ C + + + ++ P ++Q V ++ G +V
Sbjct: 1992 KVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDI 2051
Query: 1012 PQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSW 1071
P+ + + ++ + ++ G CG T ++ P ++N + W
Sbjct: 2052 PELGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQW 2111
Query: 1072 AAVE-----CPDTLD----------------PRDMCVLNPLREPFAKKECSILLSEVFEI 1110
+ CP + P C +PL C ++ +F
Sbjct: 2112 LVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPL--------CQLIKDSLFAQ 2163
Query: 1111 CHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWR--TPRLCPY 1168
CH +V +Y C+ D+C G EC AS+ AYA C Q + +DWR T C
Sbjct: 2164 CHALVPPQHYYDACVFDSC-FMPGSSLEC--ASLQAYAALCAQQNICLDWRNHTHGACLV 2220
Query: 1169 DCDFFNKVLGKGP 1181
+C + GP
Sbjct: 2221 ECPSHREYQACGP 2233
Score = 67.4 bits (163), Expect = 2e-10
Identities = 89/398 (22%), Positives = 145/398 (36%), Gaps = 67/398 (16%)
Query: 2030 CPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDC-KSANLGHL 2088
C C CSI+ ++TFDG + Y+ Q C ++++LG
Sbjct: 752 CTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDY----------CGQNSSLGS- 800
Query: 2089 NWPPFCLVMLNM----THLAHQVTIDRFNRKVTVDLQPVWPPVSR------YGFRIEDTG 2138
F ++ N+ T + I F + + L+ V + + + G
Sbjct: 801 ----FSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYTTREVG 856
Query: 2139 HMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGA 2198
++ + + I + W + ++ + + K GLCG D + ND T +D VV
Sbjct: 857 QYLVVESSTGIIVIW-DKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSE 915
Query: 2199 EDPAPFLDSWQVPSSLTSVGQTRFRPDSC---------ATTDCSPCLRMVSNRTFSACHR 2249
D F +SW+ + V P+ C A CS ++ + FS CH
Sbjct: 916 LD---FGNSWKEAPTCPDVSTN---PEPCSLNPHRRSWAEKQCS----ILKSSVFSICHS 965
Query: 2250 FVPPESFCELWIRDTKYVQQP------CVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSD 2303
V P+ F E + D+ C A+ Y C K C+ WR D CP C
Sbjct: 966 KVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACVFWRTPDLCPIFCDYY 1025
Query: 2304 STYQACVTACEPP-----KTCQ--DGILGPLDPEHCQVLGEGCV--CSEGTILHRRHSAL 2354
+ C EP +TC+ +GI + + EGC C + ++
Sbjct: 1026 NPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYL----EGCYPRCPKDRPIYEEDLKK 1081
Query: 2355 CIPEAKCAC--TDSMGVPRALGETWNSSLSGCCQHQCQ 2390
C+ KC C D+ P A T + S C + Q
Sbjct: 1082 CVTADKCGCYVEDTHYPPGASVPTEETCKSCVCTNSSQ 1119
Score = 66.6 bits (161), Expect = 3e-10
Identities = 66/274 (24%), Positives = 120/274 (43%), Gaps = 43/274 (15%)
Query: 911 STCTAYGDRHYRTFDGLPFDFVGACK---------------VHLVKSTSDVSFSVIVENV 955
+ C+ +G+ HY+TFDG F F G C VHL + VE++
Sbjct: 35 NVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQAEAPAGVESI 94
Query: 956 NCYSSGMICRKFISINVGNSLIVFDD---DSGNPSPESFLDDKQEVHTWRVGFFTLVHFP 1012
++ K +I + L V + + + SP L +K + +T +
Sbjct: 95 ------LLTIKDDTIYLTRHLAVLNGAVVSTPHYSP-GLLIEKSDAYT--------KVYS 139
Query: 1013 QEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFD-LKTINEMRTPENLELTNPQEFGSSW 1071
+ +TL+W++ + ++ +++ GLCG+++ L++ +E + L +P EFG+
Sbjct: 140 RAGLTLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDG--VLFSPLEFGNM- 196
Query: 1072 AAVECPDTL--DPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTC 1129
+ PD + DP + E A+ E +L +E F C +V + + C D C
Sbjct: 197 QKINQPDVVCEDPEEEVAPASCSEHRAECE-RLLTAEAFADCQDLVPLEPYLRACQQDRC 255
Query: 1130 GCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRT 1162
C G C C++V+ ++ QC G +WRT
Sbjct: 256 RCPGGD--TCVCSTVAEFSRQCSHAGGRPGNWRT 287
Score = 51.6 bits (122), Expect = 1e-05
Identities = 59/226 (26%), Positives = 84/226 (37%), Gaps = 39/226 (17%)
Query: 2160 MIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQ 2219
+ V + S+ Q GLCG +G +D G V A F ++W+ SS +
Sbjct: 413 LFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATG---AGFANTWKAQSSCHD--K 467
Query: 2220 TRFRPDSCATTDCSP------CLRMVSNRT-FSACHRFVPPESFCELWIRDTKYVQQP-- 2270
+ D C+ S C + T F CH V P + + DT Q
Sbjct: 468 LDWLDDPCSLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNED 527
Query: 2271 --CVALTVYVAMCHKFHVCI-EWRRS------DYCP----FLCSSDSTYQACVTACEPPK 2317
C AL+ Y C V + WR CP FL + + Q C + E
Sbjct: 528 CLCAALSSYARACTAKGVMLWGWREHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADS 587
Query: 2318 TCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCAC 2363
C +G P+D GC C + T L + C+P AKC+C
Sbjct: 588 HCLEGF-APVD---------GCGCPDHTFLDEK--GRCVPLAKCSC 621
>gi|239751787 PREDICTED: hypothetical protein XP_002348012 [Homo
sapiens]
Length = 3003
Score = 310 bits (793), Expect = 2e-83
Identities = 311/1220 (25%), Positives = 449/1220 (36%), Gaps = 196/1220 (16%)
Query: 49 HPAFCDCRRFNATGPRCQM---VYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTL 105
H C ++ G RC + + P+R C+ G H +FDG + G +Y L
Sbjct: 831 HQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLL 890
Query: 106 VGRHEPEGQ--SFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLP 163
VG +F + V N+ + GS + +RAV V + + +A + G +V +
Sbjct: 891 VGSCGQNAALPAFRVLVENEHR-GSQTVSYTRAVR---VEARGVKVAVRREYPG-QVLVD 945
Query: 164 HVMGSARLQQLAGYV---------IVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGN 214
V+ Q G V +VR T+ +D + V K+ GLCGN
Sbjct: 946 DVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGN 1005
Query: 215 NNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVY 274
N DP DDL G + + F +SWQE+ PG + P L
Sbjct: 1006 FNGDPADDLALRGGGQAANALAFGNSWQEETR---PGCGATEPGDCPKLDSLVAQQLQSK 1062
Query: 275 EQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRP 332
+C L P PF CH+ + P C D C G C ALA YA AC AG
Sbjct: 1063 NECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGAT 1122
Query: 333 LQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFED 392
+ WR++ C + C + Y C CP SC C +GC C G
Sbjct: 1123 VHPWRSE-ELCPLSCPPHSH-YEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSG 1180
Query: 393 GGCVAPAECPCEFHGTLYPPGSVVKED--CNT-CTCTSGKW-ECSTAVC----------- 437
C+ A C C GT +PPG C++ C C G C ++ C
Sbjct: 1181 ESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGG 1240
Query: 438 --------PAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSS----GTFTVTLQNAPC 485
+ C +GD H+TTFDGRR+ F TC Y+LA++ + F V +N
Sbjct: 1241 SLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAW 1300
Query: 486 GLNQDGA----CVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS- 540
G + VQ + L + R+ D+ L P +IR
Sbjct: 1301 GNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKL--------PVVLANGQIRASQH 1352
Query: 541 SVFLRVRTNVGVRVLYDREGLRLYLQ--VDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPE 598
+ + T+ G+RV YD L Y++ V + + GLCG +NG+ +DDF P G
Sbjct: 1353 GSDVVIETDFGLRVAYD---LVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQA 1409
Query: 599 STPQLFGNSWKTLSACSPLVSGSPLDP----------CDVHLQAASYSVQACSVLTGEM- 647
FGNSW+ + SP + +P P C L+ + C +L+
Sbjct: 1410 GNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTG 1469
Query: 648 -FAPCSAFLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACA 704
+ C + P + C D C G LC+ + Y C+ G V+ C
Sbjct: 1470 PLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCP 1529
Query: 705 LSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADL 764
+ C + Y C C C L++P C +D C EGC C + QA
Sbjct: 1530 MECPPNSHYELCADTCSLGCSALSAPPQC---------QDGCAEGCQCDSGFLYNGQA-- 1578
Query: 765 CVPRNQCSCHFQGVDYPPGDS----DIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNC 820
CVP QC C+ GV Y P + + CH G M C +C GQV
Sbjct: 1579 CVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKG-MVCQEH----SCKPGQV---- 1629
Query: 821 SDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGK 880
C+ LS + PC HG C
Sbjct: 1630 --------------CQPSGGILSCVTKDPC------------HGVTC------------- 1650
Query: 881 EYFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHL- 939
P TC Q G C L +TC +GD HY +FDG FDF G C L
Sbjct: 1651 ---------RPQETCKEQGGQGVC-LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLA 1700
Query: 940 ------VKSTSDVSFSVIVENVNCYSSGMICRKFISI-NVGNSLIVFDDDSG-------- 984
V + F+V +N N + + + +++ +G ++ + D+ G
Sbjct: 1701 TTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNG 1760
Query: 985 --NPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLC 1042
P S D + V + F + + +D V V + G + GLC
Sbjct: 1761 VLTALPVSVADGRISVAQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLC 1817
Query: 1043 GNFDLKTINEMRTPENLELTNPQEFGSSWAAV--------ECPDTLDPRDMCVLNPLREP 1094
GN D N+ P + +G SW A EC + C + L +
Sbjct: 1818 GNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSC---PTCPEDRLEQY 1874
Query: 1095 FAKKECSILLSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQC 1151
C L S F CH V F+ C+ D C GGD + C ++++Y C
Sbjct: 1875 EGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDRDILCKALASYVAAC 1932
Query: 1152 CQHGVAV-DWRTPRLCPYDC 1170
GV + DWR C C
Sbjct: 1933 QAAGVVIEDWRAQVGCEITC 1952
Score = 296 bits (758), Expect = 2e-79
Identities = 305/1176 (25%), Positives = 449/1176 (38%), Gaps = 199/1176 (16%)
Query: 73 PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS-----FSIQVHNDPQCG 127
P ++ C WG H +FDG + G +Y L P + F++ N + G
Sbjct: 1667 PNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNR-G 1725
Query: 128 SSPYTCSRAVSLFFVGEQ-EIHLAK----EVTHGGMRVQLPHVMGSARLQ--QLAGYVIV 180
+ + R V++ +G IH + V G+ LP + R+ Q A ++
Sbjct: 1726 NPAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALL 1785
Query: 181 RHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHS 240
+++D V + + G GLCGN + +P +D V +G L + + S
Sbjct: 1786 VADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGS 1845
Query: 241 WQEQAPNQPP---GPTTSSLPRPP--CLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPL 295
W+ AP P S P P L+Q G G + PF CHA+V P
Sbjct: 1846 WR--APGWDPLCWDECRGSCPTCPEDRLEQYEGP--GFCGPLASGTGGPFTTCHAHVPPE 1901
Query: 296 PFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYN 355
F C D+C GD C+ALA Y AC AG ++ WR Q+ C + C E + Y
Sbjct: 1902 SFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV-GCEITCPENSH-YE 1959
Query: 356 ECIACCPASC---HPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE-CPCEFHGTLYP 411
C CPASC P + E CV+GC C G + CV C C +GT +
Sbjct: 1960 VCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHE 2019
Query: 412 PGSVVKED--CNT-CTC--TSGKWECSTAVC--------------------PAECSVTGD 446
GS D C+ C C G C+ A C AEC GD
Sbjct: 2020 AGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGD 2079
Query: 447 IHFTTFDGRRYTFPATCQYILA-----KSRSSGTFTVTLQNAPCGLNQDGACVQSVSVIL 501
H+ T DG R+ F TC+Y+L+ + FTVT+ N G +Q + +SV++ +
Sbjct: 2080 PHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTLQI 2138
Query: 502 HQDPRRQVTLTQAGD-VLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREG 560
+ +TL+ L D + P+ D+ LS + V T G+ + +D +
Sbjct: 2139 Y---NHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDS 2195
Query: 561 LRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA--CSPLV 618
+ L+V + GLCG +N + DD + G P W+ A C V
Sbjct: 2196 F-VRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQGCGECV 2246
Query: 619 SGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDACRC-GQP- 674
S PC Q + AC V+ T APC + P YF+ C DAC+ G P
Sbjct: 2247 SKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPG 2306
Query: 675 CLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACG 734
LC +A Y C+ G + R C L C A Y C C +C L++PE C
Sbjct: 2307 GLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEGC- 2365
Query: 735 VDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCH 794
C EGC C D D CVP QC C G YP G+ P
Sbjct: 2366 --------ESACREGCVC--DAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPG----- 2410
Query: 795 CKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGC 854
C+ R P G V TC++
Sbjct: 2411 -----PECERRCECG--PGGHV-----------------TCQE----------------- 2429
Query: 855 ACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCT 914
G AC EEC + + CH C R C
Sbjct: 2430 ---------GAACGPHEECRL----------EDGVQACHATGCGR-------------CL 2457
Query: 915 AYGDRHYRTFDGLPFDFVGACKVHLVK----STSDVSFSVIVENVNCYSSGMICR----- 965
A G HY T DG +D G+C L + D FS+++E ++G + R
Sbjct: 2458 ANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEK---NAAGDLQRLLVTV 2514
Query: 966 --KFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQR 1023
+ +S+ G + V + P + E +V + + LL+D
Sbjct: 2515 AGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGR-------NMVLQTTKGLRLLFDGD 2567
Query: 1024 TTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAA----VECPDT 1079
+ + ++G+L GLCGNF+ ++ P ++ + FG++W A C +
Sbjct: 2568 AHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEG 2627
Query: 1080 LDPR--DMCVLNPLREPFAKKECSILLSE--VFEICHPVVDVTWFYSNCLTDTCGCSQGG 1135
P+ +C+ + + C L + F C V+ + ++ C+ D C+Q G
Sbjct: 2628 CGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDL--CAQKG 2685
Query: 1136 DCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1170
D C S++AY C GVAV WRT CP C
Sbjct: 2686 DKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHC 2721
Score = 280 bits (716), Expect = 1e-74
Identities = 247/825 (29%), Positives = 336/825 (40%), Gaps = 105/825 (12%)
Query: 60 ATGPRCQMVYNAG---PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQ-- 114
A G RCQ+V E ++CRA G H TFDG Y + G SYT+V +
Sbjct: 450 AAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLP 509
Query: 115 SFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHL---AKEVTHG--------GMRVQLP 163
+FS++ N+ + SR VS +VG + + +T G R +LP
Sbjct: 510 AFSVEAKNE-------HRGSRRVS--YVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLP 560
Query: 164 HVMGSARLQ--QLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKD 221
+ RL+ Q +V + +D + + + GLCGN N DP D
Sbjct: 561 VSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPAD 620
Query: 222 DLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEA-- 279
D +T G L D VEF SW+ + L C P G + E
Sbjct: 621 DFLTPDGALAPDAVEFASSWKLDDGDY--------LCEDGCQNNCPACTPGQAQHYEGDR 672
Query: 280 ------LLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 333
L PF CH + P PF C DLC G+ + CR L+ YA+AC + G +
Sbjct: 673 LCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISV 732
Query: 334 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVD-SEIACVDGCYCPNGLIFED 392
WR+ C + C + Y C CP SC+ A+ + S CV+GC C G +
Sbjct: 733 GDWRSP-ANCPLSCPANS-RYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASG 790
Query: 393 GGCVAPAECPCEFHGTLYPPGSVVKED--C-NTCTCTSGKWECS---TAVCPA--ECSV- 443
G CV + C C F G PG V D C CTC + + CPA CSV
Sbjct: 791 GACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQ 850
Query: 444 ----------------TGDIHFTTFDGRRYTFPATCQYILAKSRSSG----TFTVTLQNA 483
+GD H+ +FDGRR+ F TC Y+L S F V ++N
Sbjct: 851 NGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENE 910
Query: 484 PCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIP-PYTDDAFEIRRLSSV 542
G +Q + ++V V + + V G VL+ D + +P D ++ R
Sbjct: 911 HRG-SQTVSYTRAVRVEA-RGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRD 968
Query: 543 FLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQ 602
+ VRT+ G+ V YD R+ +V + E GLCG FNG+ DD G +
Sbjct: 969 AV-VRTDFGLTVTYDWNA-RVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANAL 1026
Query: 603 LFGNSW--KTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEM--FAPCSAFLSPV 658
FGNSW +T C G D + S C +L F C + L P
Sbjct: 1027 AFGNSWQEETRPGCGATEPGD-CPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQ 1085
Query: 659 PYFEQCRRDACRC-GQP-CLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPC 716
C D C GQ LC LA YA C+ G V C LSC Y C
Sbjct: 1086 GAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEAC 1145
Query: 717 VAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQ 776
C +C DL P CG EC EGC C D + C+P C C Q
Sbjct: 1146 SYGCPLSCGDLPVPGGCG---------SECHEGCVC--DEGFALSGESCLPLASCGCVHQ 1194
Query: 777 GVDYPPGDSDIPSLG---HCHCKD-GVMSCDSRA--PAAAC-PAG 814
G +PPG + P G CHC++ G++SC+S + P AC P+G
Sbjct: 1195 GTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSG 1239
Score = 254 bits (649), Expect = 9e-67
Identities = 233/821 (28%), Positives = 317/821 (38%), Gaps = 90/821 (10%)
Query: 44 GGECV-HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGS 102
GG V PA C P Q + P + C+AWG H T DG + G
Sbjct: 2040 GGSLVCTPASCGLGEVCGLLPSGQ--HGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCE 2097
Query: 103 YTLVGR-HEPE--GQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQ---EIHLAKEVTHG 156
Y L H P ++F++ V N+ + GS + +R+V+L +++
Sbjct: 2098 YLLSAPCHGPPLGAENFTVTVANEHR-GSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD 2156
Query: 157 GMRVQLPHVMGSARLQQLAGY-VIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNN 215
G+ V LP + S L+G V+V S +LA+DG S V +++ GLCGN
Sbjct: 2157 GVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNY 2216
Query: 216 NADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQ--GV 273
N DP DDL GK V E P P T P Q++ G GV
Sbjct: 2217 NQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCT------PEQQESFGGPDACGV 2270
Query: 274 YEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 333
+ L P CH V P + C D CQ G C A+A Y AC AG L
Sbjct: 2271 ISATDGPLAP----CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQL 2326
Query: 334 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDG 393
WR C + C + Y C CP SC ++ E AC +GC C G +
Sbjct: 2327 GEWRRP-DFCPLQCPAHSH-YELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGD 2384
Query: 394 GCVAPAECPCEFHGTLYP------PGSVVKEDCNT-------------------CTCTSG 428
CV +C C G YP PG + C C G
Sbjct: 2385 TCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDG 2444
Query: 429 KWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAK----SRSSGTFTVTLQNAP 484
C C C G IH+ T DGR Y +C Y+LA+ F++ L+
Sbjct: 2445 VQACHATGC-GRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNA 2503
Query: 485 CGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFL 544
G + +L + V+L Q V + + +P ++ L
Sbjct: 2504 AG---------DLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVL 2554
Query: 545 RVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLF 604
+ T G+R+L+D + L + + + GLCG FNGN DDF+ P G S+ + F
Sbjct: 2555 Q--TTKGLRLLFDGDA-HLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETF 2611
Query: 605 GNSWKTLSACSPLVSGSPLDPCDVHL--QAASY-SVQACSVLTGEM--FAPCSAFLSPVP 659
G +W+ + G C V L + A Y S +AC L FA C A LSP
Sbjct: 2612 GAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSE 2671
Query: 660 YFEQCRRDAC--RCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCV 717
YF QC D C + + LC +LA Y C+ G+ V C L C A YS C
Sbjct: 2672 YFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICT 2731
Query: 718 APCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQG 777
C +C L+ C C EGC C D +L +Q +C+P C C G
Sbjct: 2732 RTCQGSCAALSGLTGC---------TTRCFEGCEC-DDRFLLSQG-VCIPVQDCGCTHNG 2780
Query: 778 VDYPPGDSDIPS--LGHCHCKDGVMSCDSRAPAAACPAGQV 816
P S + S C C S AA CP G+V
Sbjct: 2781 RYLPVNSSLLTSDCSERCSCSS---SSGLTCQAAGCPPGRV 2818
Score = 161 bits (408), Expect = 8e-39
Identities = 154/588 (26%), Positives = 227/588 (38%), Gaps = 47/588 (7%)
Query: 30 RAKCAPSYLFSCFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVET 89
R +C P +C G C +CR + Q + G R C A G H T
Sbjct: 2416 RCECGPGGHVTCQEGAACGPHE--ECRLEDGV----QACHATGCGR---CLANGGIHYIT 2466
Query: 90 FDGLYYYLSGKGSYTL--VGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEI 147
DG Y L G SY L V +P + FSI + + L V Q +
Sbjct: 2467 LDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRL-------LVTVAGQVV 2519
Query: 148 HLAK--EVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELL 205
LA+ +VT G V LP +G R+ ++++ L +DG + + + +
Sbjct: 2520 SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFR 2579
Query: 206 GWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQ 265
G GLCGN N + DD V +G V F +W+ ++ G P CL +
Sbjct: 2580 GRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAE 2639
Query: 266 NPGTMQGVYEQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYA 323
+ E C L P PF C A +SP + C DLC GD A CR+LA Y
Sbjct: 2640 ETAPYES-NEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYT 2698
Query: 324 RACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCY 383
AC AG ++ WRT C +HC + Y+ C C SC + C +GC
Sbjct: 2699 AACQAAGVAVKPWRTD-SFCPLHCPAHSH-YSICTRTCQGSCAALSGLTGCTTRCFEGCE 2756
Query: 384 CPNGLIFEDGGCVAPAECPCEFHGTLYP-PGSVVKEDCN-TCTCTSGK-WECSTAVCP-- 438
C + + G C+ +C C +G P S++ DC+ C+C+S C A CP
Sbjct: 2757 CDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPG 2816
Query: 439 ------AE----------CSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQN 482
AE C ++ + TTFDG R + Y L+ T+
Sbjct: 2817 RVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYR 2876
Query: 483 APCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSV 542
+ ++V + VTLT V + +P + + R
Sbjct: 2877 VVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDG 2936
Query: 543 FLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDF 590
L VR GV+V G ++ + V G CG F+G+ +D+
Sbjct: 2937 SLLVRQKAGVQVWLGANG-KVAVIVSNDHAGKLCGACGNFDGDQTNDW 2983
Score = 115 bits (287), Expect = 8e-25
Identities = 111/421 (26%), Positives = 162/421 (38%), Gaps = 61/421 (14%)
Query: 798 GVMSCDSRAPA---AACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGC 854
G+ D R+PA +CPA + C + +C + S R PC+ GC
Sbjct: 729 GISVGDWRSPANCPLSCPANSRYELCGP-------ACPTSCNGAAAPSNCSGR-PCVEGC 780
Query: 855 ACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSP--C-HTCVCQRGSFQCTLHPCAS 911
C G + G AC C CT++G + PG +V + C C C + Q T S
Sbjct: 781 VCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQS 840
Query: 912 ----------------------TCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD---- 945
TC GD HY +FDG FDF+G C LV S
Sbjct: 841 CPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL 900
Query: 946 VSFSVIVENVNCYSSGMICRKFISINVGNSLI---------VFDDDSGNPSPESFLDDKQ 996
+F V+VEN + S + + + + + V DD P D
Sbjct: 901 PAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADG-- 958
Query: 997 EVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTP 1056
+V +R G +V +T+ +D V + + L GLCGNF+ +++
Sbjct: 959 QVQVFRQGRDAVVR-TDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALR 1017
Query: 1057 ENLELTNPQEFGSSWAAVECP--DTLDPRDMCVLNPL--REPFAKKECSILLSE--VFEI 1110
+ N FG+SW P +P D L+ L ++ +K EC IL F
Sbjct: 1018 GGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRE 1077
Query: 1111 CHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYD 1169
CH +D +C+ D C G C +++ YA C G V WR+ LCP
Sbjct: 1078 CHSKLDPQGAVRDCVYDR--CLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLS 1135
Query: 1170 C 1170
C
Sbjct: 1136 C 1136
Score = 98.6 bits (244), Expect = 8e-20
Identities = 82/297 (27%), Positives = 126/297 (42%), Gaps = 27/297 (9%)
Query: 895 CVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD----VSFSV 950
C G C A C A GD HY TFDG +D +G C +V+ S+ +FSV
Sbjct: 455 CQVVGGKAGCVAESTA-VCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSV 513
Query: 951 IVENVN------CYSSGMICRKF---ISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTW 1001
+N + Y + R + +S+ G V D+ + P S + + V+
Sbjct: 514 EAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQS 573
Query: 1002 RVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLEL 1061
+ F +T WD + + + A ++Q Q+ GLCGN++ ++ TP+
Sbjct: 574 GPRAVVELVFGLV-VTYDWDCQLALSLPA--RFQDQVCGLCGNYNGDPADDFLTPDGALA 630
Query: 1062 TNPQEFGSSWAAVE----CPDTLDPR-DMCVLNPLREPFAKKECSIL--LSEVFEICHPV 1114
+ EF SSW + C D C + + C +L L F +CH
Sbjct: 631 PDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDT 690
Query: 1115 VDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1170
+D F C+ D C GG+ C +SAYA C + G++V DWR+P CP C
Sbjct: 691 LDPRPFLEQCVYDL--CVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSC 745
Score = 92.4 bits (228), Expect = 6e-18
Identities = 116/501 (23%), Positives = 186/501 (37%), Gaps = 85/501 (16%)
Query: 1953 SAPALSIVEGLAEALATTTEAN-----TSTTCVPIAEQDCVRHICLEGQLIRVNQSQHC- 2006
S P+LS EG A + + TCVP+ + C+ +G+ + + +
Sbjct: 2355 SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLH----DGRYYPLGEVFYPG 2410
Query: 2007 PQGAAPPRCGILGLAVRVGGDRCCPLWEC-------AC------RCSIFPDLSFVTFDGS 2053
P+ CG G G C P EC AC RC + ++T DG
Sbjct: 2411 PECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGR 2470
Query: 2054 HVALFKEAIYILSQ-----SPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVT 2108
L Y+L+Q DE ++ + + +L L + +A QV
Sbjct: 2471 VYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRL-----------LVTVAGQVV 2519
Query: 2109 IDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTS 2168
++VTVD + V PV+ R+ G ++ T +++ + + L++ S S
Sbjct: 2520 SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLM---SIPS 2576
Query: 2169 KAQGH--GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDS 2226
+G GLCG +G+ ++D L +GS E F +W+ P S G+
Sbjct: 2577 PFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVET---FGAAWRAPGSSKGCGE------G 2627
Query: 2227 CATTDCSPCL--RMVSNRTFSACHRFVPPE---SFCELWIRDTKYVQQP----------- 2270
C C CL + AC + P+ + C+ + ++Y +Q
Sbjct: 2628 CGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDK 2687
Query: 2271 ---CVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGP 2326
C +L Y A C V ++ WR +CP C + S Y C C+ G+ G
Sbjct: 2688 AFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTG- 2746
Query: 2327 LDPEHCQV-LGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCC 2385
C EGC C + +L + +CIP C CT + S S C
Sbjct: 2747 -----CTTRCFEGCECDDRFLLSQ---GVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERC 2798
Query: 2386 QHQCQAPDTIVPVDLGCPSPR 2406
C + + GCP R
Sbjct: 2799 --SCSSSSGLTCQAAGCPPGR 2817
Score = 91.3 bits (225), Expect = 1e-17
Identities = 115/456 (25%), Positives = 171/456 (37%), Gaps = 78/456 (17%)
Query: 1962 GLAEALATTTEANTSTTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLA 2021
GLA+A+ T A+ T + E C C GQ RC +
Sbjct: 419 GLAKAIGYATAADCGRTVLSPVEPSCEGMQCAAGQ-----------------RCQV---- 457
Query: 2022 VRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQ--SPDEMLTVHVLD 2079
VGG C + E C D + TFDG + Y + + S D+ L ++
Sbjct: 458 --VGGKAGC-VAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVE 514
Query: 2080 CKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRK-VTVDLQPVWPPVS--RYGFRIED 2136
K+ + G LV + +H V++ R V VD Q PVS R+
Sbjct: 515 AKNEHRGSRRVSYVGLVTVRA--YSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQ 572
Query: 2137 TGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVG 2196
+G ++ + + + L + ++ Q GLCG +GD A+D DG++
Sbjct: 573 SGPRAVVELVFGLVVTYDWDCQLALSLPARFQD-QVCGLCGNYNGDPADDFLTPDGAL-- 629
Query: 2197 GAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCL----------RMVSNRT--- 2243
A D F SW++ D C +C C R+ T
Sbjct: 630 -APDAVEFASSWKLDDG------DYLCEDGCQN-NCPACTPGQAQHYEGDRLCGMLTKLD 681
Query: 2244 --FSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCI-EWRRSDYC 2296
F+ CH + P F E + D V C L+ Y C + + + +WR C
Sbjct: 682 GPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANC 741
Query: 2297 PFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHC--QVLGEGCVCSEGTILHRRHSAL 2354
P C ++S Y+ C AC P +C G P +C + EGCVC G +
Sbjct: 742 PLSCPANSRYELCGPAC--PTSCN----GAAAPSNCSGRPCVEGCVCLPGFV---ASGGA 792
Query: 2355 CIPEAKCACTDSMGVPRALG-ETWNSSLSGCCQHQC 2389
C+P + C CT G+ A G E W L CQ +C
Sbjct: 793 CVPASSCGCT-FQGLQLAPGQEVWADEL---CQRRC 824
Score = 90.1 bits (222), Expect = 3e-17
Identities = 122/510 (23%), Positives = 186/510 (36%), Gaps = 84/510 (16%)
Query: 1992 CLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFD 2051
C EG L+ S P A P G LG C + C+ S D + TFD
Sbjct: 1216 CQEGGLVSCESSSCGPHEACQPSGGSLG---------CVAVGSSTCQAS--GDPHYTTFD 1264
Query: 2052 GSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDR 2111
G +Y+L+Q+ +H N+ N ++ + + +++
Sbjct: 1265 GRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQ 1324
Query: 2112 FNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMI-VEASKTSKA 2170
KVTV+ + PV +I + H ++ +D ++ + + V
Sbjct: 1325 RQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQ 1384
Query: 2171 QGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQ--VPSSLTSVGQTRFRP---D 2225
Q GLCG +GD +D +GS G A + F +SW+ VP S + T P D
Sbjct: 1385 QMCGLCGNYNGDPKDDFQKPNGSQAGNANE---FGNSWEEVVPDS-PCLPPTPCPPGSED 1440
Query: 2226 SCATTDCSPCLR----------MVSNRT--FSACHRFVPPESFCELWIRDTKY----VQQ 2269
+ C P L ++S+ T S+CH+ V P+ + I D +
Sbjct: 1441 CIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSI 1500
Query: 2270 PCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTAC-------EPPKTCQD 2321
C + YV+ C +E WR +CP C +S Y+ C C P CQD
Sbjct: 1501 LCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQD 1560
Query: 2322 GILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSL 2381
G EGC C G + + C+P +C C + GV E + L
Sbjct: 1561 G------------CAEGCQCDSGFLY---NGQACVPIQQCGCYHN-GV---YYEPEQTVL 1601
Query: 2382 SGCCQHQ--CQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLC 2439
C+ Q C A +V + C +P + L TKDP C
Sbjct: 1602 IDNCRQQCTCHAGKGMVCQEHSC---KPGQVCQPSGGILSCVTKDP-------------C 1645
Query: 2440 EGLAPTCRPGHRLLTHFQEDSCCPSYSCEC 2469
G+ TCRP + C P+Y C
Sbjct: 1646 HGV--TCRPQETCKEQGGQGVCLPNYEATC 1673
Score = 84.7 bits (208), Expect = 1e-15
Identities = 105/415 (25%), Positives = 157/415 (37%), Gaps = 79/415 (19%)
Query: 2012 PPRCG---ILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS 2068
P CG + GL + G C P+ C + D +VT DG Y+LS
Sbjct: 2047 PASCGLGEVCGL-LPSGQHGCQPV--STAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAP 2103
Query: 2069 PDEMLTVHVLDCKSANLGHLNWPPFCLVMLN------MTHLAHQVTIDRFNRKVTVDLQP 2122
C LG N F + + N VT+ +N +T+ +
Sbjct: 2104 -----------CHGPPLGAEN---FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSAR- 2148
Query: 2123 VWPPVSRYG-------FRIEDTGHMYM------ILTPSDIQIQWLHSSGLMIVEASKTSK 2169
WP + F+++ H ++ + T S + + + S + + +
Sbjct: 2149 -WPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRL----RVPA 2203
Query: 2170 AQGHGLCGICDG---DAANDLTLKDGSV----VGGAEDPAPFLDSWQVPSSLTSVGQTRF 2222
A LCG+C D A+DL G VGGA+ + S PS T Q F
Sbjct: 2204 AYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECV-SKPCPSPCTPEQQESF 2262
Query: 2223 R-PDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVY 2277
PD+C + + + CH VPP + + + D VQ C A+ Y
Sbjct: 2263 GGPDACGVISAT-------DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATY 2315
Query: 2278 VAMCHKFHVCI-EWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQ-VL 2335
VA C + EWRR D+CP C + S Y+ C +C P +C PE C+
Sbjct: 2316 VAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSC--PVSCP----SLSAPEGCESAC 2369
Query: 2336 GEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQ 2390
EGCVC G +L C+P +C C G LGE + C+ +C+
Sbjct: 2370 REGCVCDAGFVL---SGDTCVPVGQCGCLHD-GRYYPLGEVFYPGPE--CERRCE 2418
Score = 78.6 bits (192), Expect = 8e-14
Identities = 118/489 (24%), Positives = 165/489 (33%), Gaps = 103/489 (21%)
Query: 1983 AEQDCVRHICLEGQLIRVN--QSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCS 2040
A++ C R G +V Q CP G RC +V+ G C P C+ S
Sbjct: 816 ADELCQRRCTCNGATHQVTCRDKQSCPAGE---RC-----SVQNGLLGCYPDRFGTCQGS 867
Query: 2041 IFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNM 2100
D +V+FDG Y+L S + + P V++
Sbjct: 868 --GDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL----------------PAFRVLVEN 909
Query: 2101 THLAHQVTIDRFNRKVTVDLQPVWPPVSRY--GFRIEDTGHMYMILTPSDIQIQWLHSSG 2158
H Q + R V V+ + V V R G + D Y+ +D Q+Q
Sbjct: 910 EHRGSQTV--SYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGR 967
Query: 2159 LMIVEA---------------SKTSKAQGHGLCGIC---DGDAANDLTLKDGSVVGGAED 2200
+V +K + LCG+C +GD A+DL L+ G G A +
Sbjct: 968 DAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGG---GQAAN 1024
Query: 2201 PAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRT----------FSACHRF 2250
F +SWQ T G P C D ++ S F CH
Sbjct: 1025 ALAFGNSWQEE---TRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSK 1081
Query: 2251 VPPESFCELWIRDTKYVQ--------QPCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCS 2301
+ P+ +RD Y + C AL Y A C + WR + CP C
Sbjct: 1082 LDPQGA----VRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCP 1137
Query: 2302 SDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKC 2361
S Y+AC C P +C D + C EGCVC EG L C+P A C
Sbjct: 1138 PHSHYEACSYGC--PLSCGDLPVPGGCGSECH---EGCVCDEGFAL---SGESCLPLASC 1189
Query: 2362 ACTDSMGVPRALGETW-------------NSSLSGCCQHQCQAPDTIVPV--DLGCPSPR 2406
C G G+T+ L C C + P LGC +
Sbjct: 1190 GCV-HQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVG 1248
Query: 2407 PESCLRFGE 2415
+C G+
Sbjct: 1249 SSTCQASGD 1257
Score = 63.9 bits (154), Expect = 2e-09
Identities = 113/434 (26%), Positives = 158/434 (36%), Gaps = 67/434 (15%)
Query: 2029 CCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS-----PDEMLTVHVLDCKSA 2083
C P +E C ++ D + +FDG Y+L+ + + LT + K+
Sbjct: 1665 CLPNYEATCW--LWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQ 1722
Query: 2084 NLGHLNWPPFCLV-MLNMTHLAHQVTIDRFN-RKVTVDLQPVWP--PVSRYGFRIEDTGH 2139
N G+ P V ++ + L ++I + KV V + V PVS RI
Sbjct: 1723 NRGN---PAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQG 1779
Query: 2140 MYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLKDGSVVGG 2197
L +D +Q + V+ + S G GLCG D + ND +G++
Sbjct: 1780 ASKALLVADFGLQVSYDWNWR-VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTL--- 1835
Query: 2198 AEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPC----------------LRMVSN 2241
AP + W S + G D C + C C L +
Sbjct: 1836 ----APSIPIWG--GSWRAPGWDPLCWDECRGS-CPTCPEDRLEQYEGPGFCGPLASGTG 1888
Query: 2242 RTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCIE-WRRSDYC 2296
F+ CH VPPESF + + D C AL YVA C V IE WR C
Sbjct: 1889 GPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGC 1948
Query: 2297 PFLCSSDSTYQACVTACEPPKTCQDGILGPL-DPEHCQ-VLGEGCVCSEGTILHRRHSAL 2354
C +S Y+ C C P +C PL P C+ EGC C G +L +
Sbjct: 1949 EITCPENSHYEVCGPPC--PASCPSP--APLTTPAVCEGPCVEGCQCDAGFVL---SADR 2001
Query: 2355 CIP-EAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRF 2413
C+P C C + A E W G C C+ G P SC
Sbjct: 2002 CVPLNNGCGCWANGTYHEAGSEFW---ADGTCSQWCRCGP-----GGGSLVCTPASC-GL 2052
Query: 2414 GEVALLLPTKDPCC 2427
GEV LLP+ C
Sbjct: 2053 GEVCGLLPSGQHGC 2066
Score = 32.7 bits (73), Expect = 5.3
Identities = 26/96 (27%), Positives = 33/96 (34%), Gaps = 17/96 (17%)
Query: 811 CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLS--VSARGPCLSGCACPQGLLRHGDACF 868
CPA + C+ RTC+ LS C GC C L C
Sbjct: 2721 CPAHSHYSICT-----------RTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCI 2769
Query: 869 LPEECPCTWKGKEYFP--GDQVMSPC-HTCVCQRGS 901
++C CT G+ Y P + S C C C S
Sbjct: 2770 PVQDCGCTHNGR-YLPVNSSLLTSDCSERCSCSSSS 2804
>gi|154146262 Fc fragment of IgG binding protein [Homo sapiens]
Length = 5405
Score = 308 bits (790), Expect = 4e-83
Identities = 310/1218 (25%), Positives = 448/1218 (36%), Gaps = 194/1218 (15%)
Query: 49 HPAFCDCRRFNATGPRCQM---VYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTL 105
H C ++ G RC + + P+R C+ G H +FDG + G +Y L
Sbjct: 831 HQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLL 890
Query: 106 VGRHEPEGQ--SFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLP 163
VG +F + V N+ + GS + +RAV V + + +A + G +V +
Sbjct: 891 VGSCGQNAALPAFRVLVENEHR-GSQTVSYTRAVR---VEARGVKVAVRREYPG-QVLVD 945
Query: 164 HVMGSARLQQLAGYV---------IVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGN 214
V+ Q G V +VR T+ +D + V K+ GLCGN
Sbjct: 946 DVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGN 1005
Query: 215 NNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVY 274
N DP DDL G + + F +SWQE+ PG + P L
Sbjct: 1006 FNGDPADDLALRGGGQAANALAFGNSWQEETR---PGCGATEPGDCPKLDSLVAQQLQSK 1062
Query: 275 EQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRP 332
+C L P PF CH+ + P C D C G C ALA YA AC AG
Sbjct: 1063 NECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGAT 1122
Query: 333 LQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFED 392
+ WR++ C + C + Y C CP SC C +GC C G
Sbjct: 1123 VHPWRSE-ELCPLSCPPHSH-YEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSG 1180
Query: 393 GGCVAPAECPCEFHGTLYPPGSVVKED--CNT-CTCTSGKW-ECSTAVC----------- 437
C+ A C C GT +PPG C++ C C G C ++ C
Sbjct: 1181 ESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGG 1240
Query: 438 --------PAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSS----GTFTVTLQNAPC 485
+ C +GD H+TTFDGRR+ F TC Y+LA++ + F V +N
Sbjct: 1241 SLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAW 1300
Query: 486 GLNQDGA----CVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS- 540
G + VQ + L + R+ D+ L P +IR
Sbjct: 1301 GNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKL--------PVVLANGQIRASQH 1352
Query: 541 SVFLRVRTNVGVRVLYDREGLRLYLQ--VDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPE 598
+ + T+ G+RV YD L Y++ V + + GLCG +NG+ +DDF P G
Sbjct: 1353 GSDVVIETDFGLRVAYD---LVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQA 1409
Query: 599 STPQLFGNSWKTLSACSPLVSGSPLDP----------CDVHLQAASYSVQACSVLTGEM- 647
FGNSW+ + SP + +P P C L+ + C +L+
Sbjct: 1410 GNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTG 1469
Query: 648 -FAPCSAFLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACA 704
+ C + P + C D C G LC+ + Y C+ G V+ C
Sbjct: 1470 PLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCP 1529
Query: 705 LSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADL 764
+ C + Y C C C L++P C +D C EGC C + QA
Sbjct: 1530 MECPPNSHYELCADTCSLGCSALSAPPQC---------QDGCAEGCQCDSGFLYNGQA-- 1578
Query: 765 CVPRNQCSCHFQGVDYPPGDS----DIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNC 820
CVP QC C+ GV Y P + + CH G M C +C GQV
Sbjct: 1579 CVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKG-MVCQEH----SCKPGQV---- 1629
Query: 821 SDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGK 880
C+ LS + PC HG C
Sbjct: 1630 --------------CQPSGGILSCVTKDPC------------HGVTC------------- 1650
Query: 881 EYFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHL- 939
P TC Q G C L +TC +GD HY +FDG FDF G C L
Sbjct: 1651 ---------RPQETCKEQGGQGVC-LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLA 1700
Query: 940 ------VKSTSDVSFSVIVENVNCYSSGMICRKFISI-NVGNSLIVFDDDSG-------- 984
V + F+V +N N + + + +++ +G ++ + D+ G
Sbjct: 1701 TTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVL 1760
Query: 985 NPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGN 1044
P S D + V + F + + +D V V + G + GLCGN
Sbjct: 1761 TALPVSVADGRISVTQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGN 1817
Query: 1045 FDLKTINEMRTPENLELTNPQEFGSSWAAV--------ECPDTLDPRDMCVLNPLREPFA 1096
D N+ P + +G SW A EC + C + L +
Sbjct: 1818 MDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSC---PTCPEDRLEQYEG 1874
Query: 1097 KKECSILLSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQ 1153
C L F CH V F+ C+ D C GGD + C ++++Y C
Sbjct: 1875 PGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDRDILCKALASYVAACQA 1932
Query: 1154 HGVAV-DWRTPRLCPYDC 1170
GV + DWR C C
Sbjct: 1933 AGVVIEDWRAQVGCEITC 1950
Score = 306 bits (785), Expect = 1e-82
Identities = 321/1217 (26%), Positives = 449/1217 (36%), Gaps = 193/1217 (15%)
Query: 44 GGECV-HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGS 102
GG V PA C P Q + P + C+AWG H T DG + G
Sbjct: 3239 GGSLVCTPASCGLGEVCGLLPSGQ--HGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCE 3296
Query: 103 YTLVGR-HEPE--GQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQ---EIHLAKEVTHG 156
Y L H P ++F++ V N+ + GS + +R+V+L +++
Sbjct: 3297 YLLSAPCHGPPLGAENFTVTVANEHR-GSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD 3355
Query: 157 GMRVQLPHVMGSARLQQLAGY-VIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNN 215
G+ V LP + S L+G V+V S +LA+DG S V +++ G GLCGN
Sbjct: 3356 GVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNY 3415
Query: 216 NADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQ--GV 273
N DP DDL GK V E P P T P Q++ G GV
Sbjct: 3416 NQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCT------PEQQESFGGPDACGV 3469
Query: 274 YEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 333
+ L P CH V P + C D CQ G C A+A Y AC AG L
Sbjct: 3470 ISATDGPLAP----CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQL 3525
Query: 334 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDG 393
+ WR C C + Y C CP SC ++ E AC +GC C G +
Sbjct: 3526 REWRRP-DFCPFQCPAHSH-YELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGD 3583
Query: 394 GCVAPAECPCEFHGTLYPPG---------------------SVVKEDCN---TCTCTSGK 429
CV +C C YP G S C TC + G
Sbjct: 3584 TCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGS 3643
Query: 430 WECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSS----GTFTVTLQNAPC 485
C AV C +GD H+TTFDG R+ F TC Y+LA++ + F V +N
Sbjct: 3644 LGC-VAVGSTTCQASGDPHYTTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAW 3702
Query: 486 GLNQDGA----CVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS- 540
G + VQ + L + R+ D+ L P +IR
Sbjct: 3703 GNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKL--------PVVLANGQIRASQH 3754
Query: 541 SVFLRVRTNVGVRVLYDREGLRLYLQ--VDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPE 598
+ + T+ G+RV YD L Y++ V + + GLCG +NG+ +DDF P G
Sbjct: 3755 GSDVVIETDFGLRVAYD---LVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQA 3811
Query: 599 STPQLFGNSWKTLSACSPLV------SGS----PLDPCDVHLQAASYSVQACSVLTGEM- 647
FGNSW+ + SP + GS P D C L+ + C +L+
Sbjct: 3812 GNANEFGNSWEEVVPDSPCLPPPTCPPGSAGCIPSDKCPPELEKKYQKEEFCGLLSSPTG 3871
Query: 648 -FAPCSAFLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACA 704
+ C + P + C D C G LC+ + Y C+ G V+ C
Sbjct: 3872 PLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRNETFCP 3931
Query: 705 LSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADL 764
+ C + Y C C C L++P C D C EGC C + QA
Sbjct: 3932 MECPQNSHYELCADTCSLGCSALSAPLQC---------PDGCAEGCQCDSGFLYNGQA-- 3980
Query: 765 CVPRNQCSCHFQGVDYPPGDSDI--PSLGHCHCKDG-VMSCDSRAPAAACPAGQVFVNCS 821
CVP QC C+ GV Y P + + C C G V+ C +C GQV
Sbjct: 3981 CVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHVGKVVVCQEH----SCKPGQV----- 4031
Query: 822 DLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKE 881
C+ LS + PC HG C
Sbjct: 4032 -------------CQPSGGILSCVTKDPC------------HGVTC-------------- 4052
Query: 882 YFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHL-- 939
P TC Q G C L +TC +GD HY +FDG FDF G C L
Sbjct: 4053 --------RPQETCKEQGGQGVC-LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLAT 4103
Query: 940 -----VKSTSDVSFSVIVENVNCYSSGMICRKFISI-NVGNSLIVFDDDSG--------N 985
V + F+V +N N + + + +++ +G ++ + D+ G
Sbjct: 4104 TGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLT 4163
Query: 986 PSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNF 1045
P S D + V + F + + +D V V + G + GLCGN
Sbjct: 4164 ALPVSVADGRISVAQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNM 4220
Query: 1046 DLKTINEMRTPENLELTNPQEFGSSWAAV--------ECPDTLDPRDMCVLNPLREPFAK 1097
D N+ P + +G SW A EC + C + L +
Sbjct: 4221 DRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSC---PTCPEDRLEQYEGP 4277
Query: 1098 KECSILLSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQH 1154
C L S F CH V F+ C+ D C GGD + C ++++Y C
Sbjct: 4278 GFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDRDILCKALASYVAACQAA 4335
Query: 1155 GVAV-DWRTPRLCPYDC 1170
GV + DWR C C
Sbjct: 4336 GVVIEDWRAQVGCEITC 4352
Score = 304 bits (778), Expect = 9e-82
Identities = 319/1217 (26%), Positives = 448/1217 (36%), Gaps = 193/1217 (15%)
Query: 44 GGECV-HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGS 102
GG V PA C P Q + P + C+AWG H T DG + G
Sbjct: 2038 GGSLVCTPASCGLGEVCGLLPSGQ--HGCQPVSTAECQAWGDPHYVTLDGHRFNFQGTCE 2095
Query: 103 YTLVGR-HEPE--GQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQ---EIHLAKEVTHG 156
Y L H P ++F++ V N+ + GS + +R+V+L +++
Sbjct: 2096 YLLSAPCHGPPLGAENFTVTVANEHR-GSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD 2154
Query: 157 GMRVQLPHVMGSARLQQLAGY-VIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNN 215
G+ V LP + S L+G V+V S +LA+DG S V +++ G GLCGN
Sbjct: 2155 GVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNY 2214
Query: 216 NADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQ--GV 273
N DP DDL GK V E P P T P Q++ G GV
Sbjct: 2215 NQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCT------PEQQESFGGPDACGV 2268
Query: 274 YEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 333
+ L P CH V P + C D CQ G C A+A Y AC AG L
Sbjct: 2269 ISATDGPLAP----CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQL 2324
Query: 334 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDG 393
+ WR C C + Y C CP SC ++ E AC +GC C G +
Sbjct: 2325 REWRRP-DFCPFQCPAHSH-YELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGD 2382
Query: 394 GCVAPAECPCEFHGTLYPPG---------------------SVVKEDCN---TCTCTSGK 429
CV +C C YP G S C TC + G
Sbjct: 2383 TCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGS 2442
Query: 430 WECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSS----GTFTVTLQNAPC 485
C AV C +GD H+TTFDGRR+ F TC Y+LA++ + F V +N
Sbjct: 2443 LGC-VAVGSTTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAW 2501
Query: 486 GLNQDGA----CVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS- 540
G + VQ + L + R+ D+ L P +IR
Sbjct: 2502 GNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKL--------PVVLANGQIRASQH 2553
Query: 541 SVFLRVRTNVGVRVLYDREGLRLYLQ--VDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPE 598
+ + T+ G+RV YD L Y++ V + + GLCG +NG+ +DDF P G
Sbjct: 2554 GSDVVIETDFGLRVAYD---LVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQA 2610
Query: 599 STPQLFGNSWKTLSACSPLV------SGS----PLDPCDVHLQAASYSVQACSVLTGEM- 647
FGNSW+ + SP + GS P + C L+ + C +L+
Sbjct: 2611 GNANEFGNSWEEVVPDSPCLPPPTCPPGSEGCIPSEECPPELEKKYQKEEFCGLLSSPTG 2670
Query: 648 -FAPCSAFLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACA 704
+ C + P + C D C G LC+ + Y C+ G V+ C
Sbjct: 2671 PLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGQVEPWRNETFCP 2730
Query: 705 LSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADL 764
+ C + Y C C C L++P C D C EGC C + QA
Sbjct: 2731 MECPQNSHYELCADTCSLGCSALSAPLQC---------PDGCAEGCQCDSGFLYNGQA-- 2779
Query: 765 CVPRNQCSCHFQGVDYPPGDSDI--PSLGHCHCKDG-VMSCDSRAPAAACPAGQVFVNCS 821
CVP QC C+ G Y P + + C C G V+ C +C GQV
Sbjct: 2780 CVPIQQCGCYHNGAYYEPEQTVLIDNCRQQCTCHVGKVVVCQEH----SCKPGQV----- 2830
Query: 822 DLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKE 881
C+ LS + PC HG C
Sbjct: 2831 -------------CQPSGGILSCVNKDPC------------HGVTC-------------- 2851
Query: 882 YFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHL-- 939
P TC Q G C L +TC +GD HY +FDG FDF G C L
Sbjct: 2852 --------RPQETCKEQGGQGVC-LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLAT 2902
Query: 940 -----VKSTSDVSFSVIVENVNCYSSGMICRKFISI-NVGNSLIVFDDDSG--------N 985
V + F+V +N N + + + +++ +G ++ + D+ G
Sbjct: 2903 TGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLT 2962
Query: 986 PSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNF 1045
P S D + V + F + + +D V V + G + GLCGN
Sbjct: 2963 ALPVSVADGRISVTQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNM 3019
Query: 1046 DLKTINEMRTPENLELTNPQEFGSSWAAV--------ECPDTLDPRDMCVLNPLREPFAK 1097
D N+ P + +G SW A EC + C + L +
Sbjct: 3020 DRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSC---PTCPEDRLEQYEGP 3076
Query: 1098 KECSILLSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQH 1154
C L F CH V F+ C+ D C GGD + C ++++Y C
Sbjct: 3077 GFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDRDILCKALASYVAACQAA 3134
Query: 1155 GVAV-DWRTPRLCPYDC 1170
GV + DWR C C
Sbjct: 3135 GVVIEDWRAQVGCEITC 3151
Score = 298 bits (762), Expect = 7e-80
Identities = 305/1174 (25%), Positives = 450/1174 (38%), Gaps = 197/1174 (16%)
Query: 73 PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS-----FSIQVHNDPQCG 127
P ++ C WG H +FDG + G +Y L P + F++ N + G
Sbjct: 4069 PNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNR-G 4127
Query: 128 SSPYTCSRAVSLFFVGEQ-EIHLAK--EVTHGGMRVQLPHVMGSARLQ--QLAGYVIVRH 182
+ + R V++ +G IH + +V G+ LP + R+ Q A ++
Sbjct: 4128 NPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVA 4187
Query: 183 QSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ 242
+++D V + + G GLCGN + +P +D V +G L + + SW+
Sbjct: 4188 DFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWR 4247
Query: 243 EQAPNQPP---GPTTSSLPRPP--CLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPF 297
AP P S P P L+Q G G + PF CHA+V P F
Sbjct: 4248 --APGWDPLCWDECRGSCPTCPEDRLEQYEGP--GFCGPLSSGTGGPFTTCHAHVPPESF 4303
Query: 298 TASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNEC 357
C D+C GD C+ALA Y AC AG ++ WR Q+ C + C E + Y C
Sbjct: 4304 FKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV-GCEITCPENSH-YEVC 4361
Query: 358 IACCPASC---HPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE-CPCEFHGTLYPPG 413
CPASC P + E CV+GC C G + CV C C +GT + G
Sbjct: 4362 GPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAG 4421
Query: 414 SVVKED--CNT-CTC--TSGKWECSTAVC--------------------PAECSVTGDIH 448
S D C+ C C G C+ A C AEC GD H
Sbjct: 4422 SEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPH 4481
Query: 449 FTTFDGRRYTFPATCQYILA-----KSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQ 503
+ T DG R+ F TC+Y+L+ + FTVT+ N G +Q + +SV++ ++
Sbjct: 4482 YVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTLQIY- 4539
Query: 504 DPRRQVTLTQAGD-VLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLR 562
+TL+ L D + P+ D+ LS + V T G+ + +D +
Sbjct: 4540 --NHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSF- 4596
Query: 563 LYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA--CSPLVSG 620
+ L+V + GLCG +N + DD + G P W+ A C VS
Sbjct: 4597 VRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQGCGECVSK 4648
Query: 621 SPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDACRC-GQP-CL 676
PC Q + AC V+ T APC + P YF+ C DAC+ G P L
Sbjct: 4649 PCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGL 4708
Query: 677 CATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVD 736
C +A Y C+ G + R C L C A Y C C +C L++PE C
Sbjct: 4709 CPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEGC--- 4765
Query: 737 GGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCHCK 796
C EGC C D D CVP QC C G YP G+ P
Sbjct: 4766 ------ESACREGCVC--DAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPG------- 4810
Query: 797 DGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCAC 856
C+ R P G V TC++
Sbjct: 4811 ---PECERRCECG--PGGHV-----------------TCQE------------------- 4829
Query: 857 PQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAY 916
G AC EEC + + CH C R C A
Sbjct: 4830 -------GAACGPHEECRL----------EDGVQACHATGCGR-------------CLAN 4859
Query: 917 GDRHYRTFDGLPFDFVGACKVHLVK----STSDVSFSVIVENVNCYSSGMICR------- 965
G HY T DG +D G+C L + D FS+++E ++G + R
Sbjct: 4860 GGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEK---NAAGDLQRLLVTVAG 4916
Query: 966 KFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTT 1025
+ +S+ G + V + P + E +V + + LL+D
Sbjct: 4917 QVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGR-------NMVLQTTKGLRLLFDGDAH 4969
Query: 1026 VHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAA----VECPDTLD 1081
+ + ++G+L GLCGNF+ ++ P ++ + FG++W A C +
Sbjct: 4970 LLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCG 5029
Query: 1082 PR--DMCVLNPLREPFAKKECSILLSE--VFEICHPVVDVTWFYSNCLTDTCGCSQGGDC 1137
P+ +C+ + + C L + F C V+ + ++ C+ D C+Q GD
Sbjct: 5030 PQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDL--CAQKGDK 5087
Query: 1138 ECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1170
C S++AY C GVAV WRT CP C
Sbjct: 5088 AFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHC 5121
Score = 280 bits (716), Expect = 1e-74
Identities = 247/825 (29%), Positives = 336/825 (40%), Gaps = 105/825 (12%)
Query: 60 ATGPRCQMVYNAG---PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQ-- 114
A G RCQ+V E ++CRA G H TFDG Y + G SYT+V +
Sbjct: 450 AAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLP 509
Query: 115 SFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHL---AKEVTHG--------GMRVQLP 163
+FS++ N+ + SR VS +VG + + +T G R +LP
Sbjct: 510 AFSVEAKNE-------HRGSRRVS--YVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLP 560
Query: 164 HVMGSARLQ--QLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKD 221
+ RL+ Q +V + +D + + + GLCGN N DP D
Sbjct: 561 VSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPAD 620
Query: 222 DLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEA-- 279
D +T G L D VEF SW+ + L C P G + E
Sbjct: 621 DFLTPDGALAPDAVEFASSWKLDDGDY--------LCEDGCQNNCPACTPGQAQHYEGDR 672
Query: 280 ------LLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 333
L PF CH + P PF C DLC G+ + CR L+ YA+AC + G +
Sbjct: 673 LCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISV 732
Query: 334 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVD-SEIACVDGCYCPNGLIFED 392
WR+ C + C + Y C CP SC+ A+ + S CV+GC C G +
Sbjct: 733 GDWRSP-ANCPLSCPANS-RYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASG 790
Query: 393 GGCVAPAECPCEFHGTLYPPGSVVKED--C-NTCTCTSGKWECS---TAVCPA--ECSV- 443
G CV + C C F G PG V D C CTC + + CPA CSV
Sbjct: 791 GACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQ 850
Query: 444 ----------------TGDIHFTTFDGRRYTFPATCQYILAKSRSSG----TFTVTLQNA 483
+GD H+ +FDGRR+ F TC Y+L S F V ++N
Sbjct: 851 NGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENE 910
Query: 484 PCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIP-PYTDDAFEIRRLSSV 542
G +Q + ++V V + + V G VL+ D + +P D ++ R
Sbjct: 911 HRG-SQTVSYTRAVRVEA-RGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRD 968
Query: 543 FLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQ 602
+ VRT+ G+ V YD R+ +V + E GLCG FNG+ DD G +
Sbjct: 969 AV-VRTDFGLTVTYDWNA-RVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANAL 1026
Query: 603 LFGNSW--KTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEM--FAPCSAFLSPV 658
FGNSW +T C G D + S C +L F C + L P
Sbjct: 1027 AFGNSWQEETRPGCGATEPGD-CPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQ 1085
Query: 659 PYFEQCRRDACRC-GQP-CLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPC 716
C D C GQ LC LA YA C+ G V C LSC Y C
Sbjct: 1086 GAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEAC 1145
Query: 717 VAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQ 776
C +C DL P CG EC EGC C D + C+P C C Q
Sbjct: 1146 SYGCPLSCGDLPVPGGCG---------SECHEGCVC--DEGFALSGESCLPLASCGCVHQ 1194
Query: 777 GVDYPPGDSDIPSLG---HCHCKD-GVMSCDSRA--PAAAC-PAG 814
G +PPG + P G CHC++ G++SC+S + P AC P+G
Sbjct: 1195 GTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSG 1239
Score = 254 bits (649), Expect = 9e-67
Identities = 233/821 (28%), Positives = 317/821 (38%), Gaps = 90/821 (10%)
Query: 44 GGECV-HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGS 102
GG V PA C P Q + P + C+AWG H T DG + G
Sbjct: 4440 GGSLVCTPASCGLGEVCGLLPSGQ--HGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCE 4497
Query: 103 YTLVGR-HEPE--GQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQ---EIHLAKEVTHG 156
Y L H P ++F++ V N+ + GS + +R+V+L +++
Sbjct: 4498 YLLSAPCHGPPLGAENFTVTVANEHR-GSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD 4556
Query: 157 GMRVQLPHVMGSARLQQLAGY-VIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNN 215
G+ V LP + S L+G V+V S +LA+DG S V +++ GLCGN
Sbjct: 4557 GVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNY 4616
Query: 216 NADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQ--GV 273
N DP DDL GK V E P P T P Q++ G GV
Sbjct: 4617 NQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCT------PEQQESFGGPDACGV 4670
Query: 274 YEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 333
+ L P CH V P + C D CQ G C A+A Y AC AG L
Sbjct: 4671 ISATDGPLAP----CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQL 4726
Query: 334 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDG 393
WR C + C + Y C CP SC ++ E AC +GC C G +
Sbjct: 4727 GEWRRP-DFCPLQCPAHSH-YELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGD 4784
Query: 394 GCVAPAECPCEFHGTLYP------PGSVVKEDCNT-------------------CTCTSG 428
CV +C C G YP PG + C C G
Sbjct: 4785 TCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDG 4844
Query: 429 KWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAK----SRSSGTFTVTLQNAP 484
C C C G IH+ T DGR Y +C Y+LA+ F++ L+
Sbjct: 4845 VQACHATGC-GRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNA 4903
Query: 485 CGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFL 544
G + +L + V+L Q V + + +P ++ L
Sbjct: 4904 AG---------DLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVL 4954
Query: 545 RVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLF 604
+ T G+R+L+D + L + + + GLCG FNGN DDF+ P G S+ + F
Sbjct: 4955 Q--TTKGLRLLFDGDA-HLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETF 5011
Query: 605 GNSWKTLSACSPLVSGSPLDPCDVHL--QAASY-SVQACSVLTGEM--FAPCSAFLSPVP 659
G +W+ + G C V L + A Y S +AC L FA C A LSP
Sbjct: 5012 GAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSE 5071
Query: 660 YFEQCRRDAC--RCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCV 717
YF QC D C + + LC +LA Y C+ G+ V C L C A YS C
Sbjct: 5072 YFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICT 5131
Query: 718 APCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQG 777
C +C L+ C C EGC C D +L +Q +C+P C C G
Sbjct: 5132 RTCQGSCAALSGLTGC---------TTRCFEGCEC-DDRFLLSQG-VCIPVQDCGCTHNG 5180
Query: 778 VDYPPGDSDIPS--LGHCHCKDGVMSCDSRAPAAACPAGQV 816
P S + S C C S AA CP G+V
Sbjct: 5181 RYLPVNSSLLTSDCSERCSCSS---SSGLTCQAAGCPPGRV 5218
Score = 248 bits (634), Expect = 5e-65
Identities = 229/809 (28%), Positives = 327/809 (40%), Gaps = 102/809 (12%)
Query: 73 PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS-----FSIQVHNDPQCG 127
P ++ C WG H +FDG + G +Y L P + F++ N + G
Sbjct: 1667 PNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNR-G 1725
Query: 128 SSPYTCSRAVSLFFVGEQ-EIHLAK--EVTHGGMRVQLPHVMGSARLQ--QLAGYVIVRH 182
+ + R V++ +G IH + +V G+ LP + R+ Q A ++
Sbjct: 1726 NPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVA 1785
Query: 183 QSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ 242
+++D V + + G GLCGN + +P +D V +G L + + SW+
Sbjct: 1786 DFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWR 1845
Query: 243 EQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEAL-----LRP----PFDACHAYVS 293
AP P L C P + EQ E L P PF CHA+V
Sbjct: 1846 --APGWDP------LCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVP 1897
Query: 294 PLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFT 353
P F C D+C GD C+ALA Y AC AG ++ WR Q+ C + C E +
Sbjct: 1898 PESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV-GCEITCPENSH- 1955
Query: 354 YNECIACCPASC---HPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE-CPCEFHGTL 409
Y C + CPASC P + E CV+GC C G + CV C C +GT
Sbjct: 1956 YEVCGSPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTY 2015
Query: 410 YPPGSVVKED--CNT-CTC--TSGKWECSTAVC--------------------PAECSVT 444
+ GS D C+ C C G C+ A C AEC
Sbjct: 2016 HEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAW 2075
Query: 445 GDIHFTTFDGRRYTFPATCQYILA-----KSRSSGTFTVTLQNAPCGLNQDGACVQSVSV 499
GD H+ T DG R+ F TC+Y+L+ + FTVT+ N G +Q + +SV++
Sbjct: 2076 GDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTL 2134
Query: 500 ILHQDPRRQVTLTQAGD-VLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDR 558
++ +TL+ L D + P+ D+ LS + V T G+ + +D
Sbjct: 2135 QIY---NHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDG 2191
Query: 559 EGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA--CSP 616
+ + L+V + GLCG +N + DD + G P W+ A C
Sbjct: 2192 DSF-VRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQGCGE 2242
Query: 617 LVSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDACRC-GQ 673
VS PC Q + AC V+ T APC + P YF+ C DAC+ G
Sbjct: 2243 CVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGH 2302
Query: 674 P-CLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEA 732
P LC +A Y C+ G + R C C A Y C C +C L++PE
Sbjct: 2303 PGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPEG 2362
Query: 733 CGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLG- 791
C C EGC C D D CVP QC C YP G + P G
Sbjct: 2363 C---------ESACREGCVC--DAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGC 2411
Query: 792 --HCHCKD-GVMSCD--SRAPAAAC-PAG 814
C C++ G +SC+ S P C P+G
Sbjct: 2412 DSLCRCREGGEVSCEPSSCGPHETCRPSG 2440
Score = 248 bits (634), Expect = 5e-65
Identities = 240/854 (28%), Positives = 339/854 (39%), Gaps = 115/854 (13%)
Query: 33 CAPSY-LFSCFNGGECVHPAFC----DCRRFNATGPRCQMVYNAGPERDSICRAWGQHHV 87
C PS + SC N C H C C+ G P ++ C WG H
Sbjct: 2831 CQPSGGILSCVNKDPC-HGVTCRPQETCKEQGGQGVCL-------PNYEATCWLWGDPHY 2882
Query: 88 ETFDGLYYYLSGKGSYTLVGRHEPEGQS-----FSIQVHNDPQCGSSPYTCSRAVSLFFV 142
+FDG + G +Y L P + F++ N + G+ + R V++ +
Sbjct: 2883 HSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNR-GNPAVSYVRVVTVAAL 2941
Query: 143 GEQ-EIHLAK--EVTHGGMRVQLPHVMGSARLQ--QLAGYVIVRHQSAFTLAWDGASAVY 197
G IH + +V G+ LP + R+ Q A ++ +++D V
Sbjct: 2942 GTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVD 3001
Query: 198 IKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSL 257
+ + G GLCGN + +P +D V +G L + + SW+ AP P L
Sbjct: 3002 VTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWR--APGWDP------L 3053
Query: 258 PRPPCLQQNPGTMQGVYEQCEAL-----LRP----PFDACHAYVSPLPFTASCTSDLCQS 308
C P + EQ E L P PF CHA+V P F C D+C
Sbjct: 3054 CWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMG 3113
Query: 309 MGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASC--- 365
GD C+ALA Y AC AG ++ WR Q+ C + C E + Y C CPASC
Sbjct: 3114 GGDRDILCKALASYVAACQAAGVVIEDWRAQV-GCEITCPENSH-YEVCGPPCPASCPSP 3171
Query: 366 HPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE-CPCEFHGTLYPPGSVVKED--CNT 422
P + E CV+GC C G + CV C C +GT + GS D C+
Sbjct: 3172 APLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQ 3231
Query: 423 -CTC--TSGKWECSTAVC--------------------PAECSVTGDIHFTTFDGRRYTF 459
C C G C+ A C AEC GD H+ T DG R+ F
Sbjct: 3232 WCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDF 3291
Query: 460 PATCQYILA-----KSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQA 514
TC+Y+L+ + FTVT+ N G +Q + +SV++ ++ +TL+
Sbjct: 3292 QGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTLQIY---NHSLTLSAR 3347
Query: 515 GD-VLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVE 573
L D + P+ D+ LS + V T G+ + +D + + L+V +
Sbjct: 3348 WPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSF-VRLRVPAAYAG 3406
Query: 574 DTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA--CSPLVSGSPLDPCDVHLQ 631
GLCG +N + DD + G P W+ A C VS PC Q
Sbjct: 3407 SLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQGCGECVSKPCPSPCTPEQQ 3458
Query: 632 AASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDACRC-GQP-CLCATLAHYAHLC 687
+ AC V+ T APC + P YF+ C DAC+ G P LC +A Y C
Sbjct: 3459 ESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAAC 3518
Query: 688 RRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECV 747
+ G + R C C A Y C C +C L++PE C C
Sbjct: 3519 QAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPEGC---------ESACR 3569
Query: 748 EGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLG---HCHCKD-GVMSCD 803
EGC C D D CVP QC C YP G + P G C C++ G +SC+
Sbjct: 3570 EGCVC--DAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCE 3627
Query: 804 --SRAPAAAC-PAG 814
S P C P+G
Sbjct: 3628 PSSCGPHETCRPSG 3641
Score = 161 bits (408), Expect = 8e-39
Identities = 154/588 (26%), Positives = 227/588 (38%), Gaps = 47/588 (7%)
Query: 30 RAKCAPSYLFSCFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVET 89
R +C P +C G C +CR + Q + G R C A G H T
Sbjct: 4816 RCECGPGGHVTCQEGAACGPHE--ECRLEDGV----QACHATGCGR---CLANGGIHYIT 4866
Query: 90 FDGLYYYLSGKGSYTL--VGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEI 147
DG Y L G SY L V +P + FSI + + L V Q +
Sbjct: 4867 LDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRL-------LVTVAGQVV 4919
Query: 148 HLAK--EVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELL 205
LA+ +VT G V LP +G R+ ++++ L +DG + + + +
Sbjct: 4920 SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFR 4979
Query: 206 GWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQ 265
G GLCGN N + DD V +G V F +W+ ++ G P CL +
Sbjct: 4980 GRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAE 5039
Query: 266 NPGTMQGVYEQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYA 323
+ E C L P PF C A +SP + C DLC GD A CR+LA Y
Sbjct: 5040 ETAPYES-NEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYT 5098
Query: 324 RACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCY 383
AC AG ++ WRT C +HC + Y+ C C SC + C +GC
Sbjct: 5099 AACQAAGVAVKPWRTD-SFCPLHCPAHSH-YSICTRTCQGSCAALSGLTGCTTRCFEGCE 5156
Query: 384 CPNGLIFEDGGCVAPAECPCEFHGTLYP-PGSVVKEDCN-TCTCTSGK-WECSTAVCP-- 438
C + + G C+ +C C +G P S++ DC+ C+C+S C A CP
Sbjct: 5157 CDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPG 5216
Query: 439 ------AE----------CSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQN 482
AE C ++ + TTFDG R + Y L+ T+
Sbjct: 5217 RVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYR 5276
Query: 483 APCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSV 542
+ ++V + VTLT V + +P + + R
Sbjct: 5277 VVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDG 5336
Query: 543 FLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDF 590
L VR GV+V G ++ + V G CG F+G+ +D+
Sbjct: 5337 SLLVRQKAGVQVWLGANG-KVAVIVSNDHAGKLCGACGNFDGDQTNDW 5383
Score = 115 bits (287), Expect = 8e-25
Identities = 111/421 (26%), Positives = 162/421 (38%), Gaps = 61/421 (14%)
Query: 798 GVMSCDSRAPA---AACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGC 854
G+ D R+PA +CPA + C + +C + S R PC+ GC
Sbjct: 729 GISVGDWRSPANCPLSCPANSRYELCGP-------ACPTSCNGAAAPSNCSGR-PCVEGC 780
Query: 855 ACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSP--C-HTCVCQRGSFQCTLHPCAS 911
C G + G AC C CT++G + PG +V + C C C + Q T S
Sbjct: 781 VCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQS 840
Query: 912 ----------------------TCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD---- 945
TC GD HY +FDG FDF+G C LV S
Sbjct: 841 CPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL 900
Query: 946 VSFSVIVENVNCYSSGMICRKFISINVGNSLI---------VFDDDSGNPSPESFLDDKQ 996
+F V+VEN + S + + + + + V DD P D
Sbjct: 901 PAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADG-- 958
Query: 997 EVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTP 1056
+V +R G +V +T+ +D V + + L GLCGNF+ +++
Sbjct: 959 QVQVFRQGRDAVVR-TDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALR 1017
Query: 1057 ENLELTNPQEFGSSWAAVECP--DTLDPRDMCVLNPL--REPFAKKECSILLSE--VFEI 1110
+ N FG+SW P +P D L+ L ++ +K EC IL F
Sbjct: 1018 GGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRE 1077
Query: 1111 CHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYD 1169
CH +D +C+ D C G C +++ YA C G V WR+ LCP
Sbjct: 1078 CHSKLDPQGAVRDCVYDR--CLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLS 1135
Query: 1170 C 1170
C
Sbjct: 1136 C 1136
Score = 98.6 bits (244), Expect = 8e-20
Identities = 82/297 (27%), Positives = 126/297 (42%), Gaps = 27/297 (9%)
Query: 895 CVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD----VSFSV 950
C G C A C A GD HY TFDG +D +G C +V+ S+ +FSV
Sbjct: 455 CQVVGGKAGCVAESTA-VCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSV 513
Query: 951 IVENVN------CYSSGMICRKF---ISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTW 1001
+N + Y + R + +S+ G V D+ + P S + + V+
Sbjct: 514 EAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQS 573
Query: 1002 RVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLEL 1061
+ F +T WD + + + A ++Q Q+ GLCGN++ ++ TP+
Sbjct: 574 GPRAVVELVFGLV-VTYDWDCQLALSLPA--RFQDQVCGLCGNYNGDPADDFLTPDGALA 630
Query: 1062 TNPQEFGSSWAAVE----CPDTLDPR-DMCVLNPLREPFAKKECSIL--LSEVFEICHPV 1114
+ EF SSW + C D C + + C +L L F +CH
Sbjct: 631 PDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDT 690
Query: 1115 VDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1170
+D F C+ D C GG+ C +SAYA C + G++V DWR+P CP C
Sbjct: 691 LDPRPFLEQCVYDL--CVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSC 745
Score = 92.4 bits (228), Expect = 6e-18
Identities = 116/501 (23%), Positives = 186/501 (37%), Gaps = 85/501 (16%)
Query: 1953 SAPALSIVEGLAEALATTTEAN-----TSTTCVPIAEQDCVRHICLEGQLIRVNQSQHC- 2006
S P+LS EG A + + TCVP+ + C+ +G+ + + +
Sbjct: 4755 SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLH----DGRYYPLGEVFYPG 4810
Query: 2007 PQGAAPPRCGILGLAVRVGGDRCCPLWEC-------AC------RCSIFPDLSFVTFDGS 2053
P+ CG G G C P EC AC RC + ++T DG
Sbjct: 4811 PECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGR 4870
Query: 2054 HVALFKEAIYILSQ-----SPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVT 2108
L Y+L+Q DE ++ + + +L L + +A QV
Sbjct: 4871 VYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRL-----------LVTVAGQVV 4919
Query: 2109 IDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTS 2168
++VTVD + V PV+ R+ G ++ T +++ + + L++ S S
Sbjct: 4920 SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLM---SIPS 4976
Query: 2169 KAQGH--GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDS 2226
+G GLCG +G+ ++D L +GS E F +W+ P S G+
Sbjct: 4977 PFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVET---FGAAWRAPGSSKGCGE------G 5027
Query: 2227 CATTDCSPCL--RMVSNRTFSACHRFVPPE---SFCELWIRDTKYVQQP----------- 2270
C C CL + AC + P+ + C+ + ++Y +Q
Sbjct: 5028 CGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDK 5087
Query: 2271 ---CVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGP 2326
C +L Y A C V ++ WR +CP C + S Y C C+ G+ G
Sbjct: 5088 AFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTG- 5146
Query: 2327 LDPEHCQV-LGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCC 2385
C EGC C + +L + +CIP C CT + S S C
Sbjct: 5147 -----CTTRCFEGCECDDRFLLSQ---GVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERC 5198
Query: 2386 QHQCQAPDTIVPVDLGCPSPR 2406
C + + GCP R
Sbjct: 5199 --SCSSSSGLTCQAAGCPPGR 5217
Score = 91.3 bits (225), Expect = 1e-17
Identities = 115/456 (25%), Positives = 171/456 (37%), Gaps = 78/456 (17%)
Query: 1962 GLAEALATTTEANTSTTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLA 2021
GLA+A+ T A+ T + E C C GQ RC +
Sbjct: 419 GLAKAIGYATAADCGRTVLSPVEPSCEGMQCAAGQ-----------------RCQV---- 457
Query: 2022 VRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQ--SPDEMLTVHVLD 2079
VGG C + E C D + TFDG + Y + + S D+ L ++
Sbjct: 458 --VGGKAGC-VAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVE 514
Query: 2080 CKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRK-VTVDLQPVWPPVS--RYGFRIED 2136
K+ + G LV + +H V++ R V VD Q PVS R+
Sbjct: 515 AKNEHRGSRRVSYVGLVTVRA--YSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQ 572
Query: 2137 TGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVG 2196
+G ++ + + + L + ++ Q GLCG +GD A+D DG++
Sbjct: 573 SGPRAVVELVFGLVVTYDWDCQLALSLPARFQD-QVCGLCGNYNGDPADDFLTPDGAL-- 629
Query: 2197 GAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCL----------RMVSNRT--- 2243
A D F SW++ D C +C C R+ T
Sbjct: 630 -APDAVEFASSWKLDDG------DYLCEDGCQN-NCPACTPGQAQHYEGDRLCGMLTKLD 681
Query: 2244 --FSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCI-EWRRSDYC 2296
F+ CH + P F E + D V C L+ Y C + + + +WR C
Sbjct: 682 GPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANC 741
Query: 2297 PFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHC--QVLGEGCVCSEGTILHRRHSAL 2354
P C ++S Y+ C AC P +C G P +C + EGCVC G +
Sbjct: 742 PLSCPANSRYELCGPAC--PTSCN----GAAAPSNCSGRPCVEGCVCLPGFV---ASGGA 792
Query: 2355 CIPEAKCACTDSMGVPRALG-ETWNSSLSGCCQHQC 2389
C+P + C CT G+ A G E W L CQ +C
Sbjct: 793 CVPASSCGCT-FQGLQLAPGQEVWADEL---CQRRC 824
Score = 90.1 bits (222), Expect = 3e-17
Identities = 122/510 (23%), Positives = 186/510 (36%), Gaps = 84/510 (16%)
Query: 1992 CLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFD 2051
C EG L+ S P A P G LG C + C+ S D + TFD
Sbjct: 1216 CQEGGLVSCESSSCGPHEACQPSGGSLG---------CVAVGSSTCQAS--GDPHYTTFD 1264
Query: 2052 GSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDR 2111
G +Y+L+Q+ +H N+ N ++ + + +++
Sbjct: 1265 GRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQ 1324
Query: 2112 FNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMI-VEASKTSKA 2170
KVTV+ + PV +I + H ++ +D ++ + + V
Sbjct: 1325 RQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQ 1384
Query: 2171 QGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQ--VPSSLTSVGQTRFRP---D 2225
Q GLCG +GD +D +GS G A + F +SW+ VP S + T P D
Sbjct: 1385 QMCGLCGNYNGDPKDDFQKPNGSQAGNANE---FGNSWEEVVPDS-PCLPPTPCPPGSED 1440
Query: 2226 SCATTDCSPCLR----------MVSNRT--FSACHRFVPPESFCELWIRDTKY----VQQ 2269
+ C P L ++S+ T S+CH+ V P+ + I D +
Sbjct: 1441 CIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSI 1500
Query: 2270 PCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTAC-------EPPKTCQD 2321
C + YV+ C +E WR +CP C +S Y+ C C P CQD
Sbjct: 1501 LCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQD 1560
Query: 2322 GILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSL 2381
G EGC C G + + C+P +C C + GV E + L
Sbjct: 1561 G------------CAEGCQCDSGFLY---NGQACVPIQQCGCYHN-GV---YYEPEQTVL 1601
Query: 2382 SGCCQHQ--CQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLC 2439
C+ Q C A +V + C +P + L TKDP C
Sbjct: 1602 IDNCRQQCTCHAGKGMVCQEHSC---KPGQVCQPSGGILSCVTKDP-------------C 1645
Query: 2440 EGLAPTCRPGHRLLTHFQEDSCCPSYSCEC 2469
G+ TCRP + C P+Y C
Sbjct: 1646 HGV--TCRPQETCKEQGGQGVCLPNYEATC 1673
Score = 86.3 bits (212), Expect = 4e-16
Identities = 87/371 (23%), Positives = 133/371 (35%), Gaps = 62/371 (16%)
Query: 848 GPCLSGCACPQGLLRHGDACF-LPEECPCTWKGKEY------FPGDQVMSPCHTCVCQRG 900
GPC+ GC C G + D C L C C W Y F D S C G
Sbjct: 3182 GPCVEGCQCDAGFVLSADRCVPLNNGCGC-WANGTYHEAGSEFWADGTCSQWCRCGPGGG 3240
Query: 901 SFQCTLHPCA--------------------STCTAYGDRHYRTFDGLPFDFVGACKVHLV 940
S CT C + C A+GD HY T DG FDF G C+ L
Sbjct: 3241 SLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLS 3300
Query: 941 -----KSTSDVSFSVIVENVNCYSSGMICRKFISINVGNSLIVFDD--------DSGNPS 987
+F+V V N + S + + +++ + N + D +
Sbjct: 3301 APCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVT 3360
Query: 988 PESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDL 1047
LD H + +V ++L +D + V ++ + G L GLCGN++
Sbjct: 3361 LPFQLDSLLHAH---LSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQ 3417
Query: 1048 KTINEMRT----PENLELTNPQEFGSSWAAVECPDTLDPRDMCVLNPLREPFAKKECSIL 1103
++++ P ++ Q G + CP P +E F + +
Sbjct: 3418 DPADDLKAVGGKPAGWQVGGAQGCGEC-VSKPCPSPCTPEQ-------QESFGGPDACGV 3469
Query: 1104 LSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-D 1159
+S CH +V ++ CL D C G C +V+ Y C G + +
Sbjct: 3470 ISATDGPLAPCHGLVPPAQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLRE 3527
Query: 1160 WRTPRLCPYDC 1170
WR P CP+ C
Sbjct: 3528 WRRPDFCPFQC 3538
Score = 85.9 bits (211), Expect = 5e-16
Identities = 100/388 (25%), Positives = 148/388 (38%), Gaps = 76/388 (19%)
Query: 2012 PPRCG---ILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS 2068
P CG + GL + G C P+ C + D +VT DG Y+LS
Sbjct: 2045 PASCGLGEVCGL-LPSGQHGCQPV--STAECQAWGDPHYVTLDGHRFNFQGTCEYLLSAP 2101
Query: 2069 PDEMLTVHVLDCKSANLGHLNWPPFCLVMLN------MTHLAHQVTIDRFNRKVTVDLQP 2122
C LG N F + + N VT+ +N +T+ +
Sbjct: 2102 -----------CHGPPLGAEN---FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSAR- 2146
Query: 2123 VWPPVSRYG-------FRIEDTGHMYM------ILTPSDIQIQWLHSSGLMIVEASKTSK 2169
WP + F+++ H ++ + T S + + + S + + +
Sbjct: 2147 -WPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRL----RVPA 2201
Query: 2170 AQGHGLCGICDG---DAANDLTLKDGSV----VGGAEDPAPFLDSWQVPSSLTSVGQTRF 2222
A LCG+C D A+DL G VGGA+ + S PS T Q F
Sbjct: 2202 AYAGSLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECV-SKPCPSPCTPEQQESF 2260
Query: 2223 R-PDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVY 2277
PD+C + + + CH VPP + + + D VQ C A+ Y
Sbjct: 2261 GGPDACGVISAT-------DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATY 2313
Query: 2278 VAMCHKFHVCI-EWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQ-VL 2335
VA C + EWRR D+CPF C + S Y+ C +C P +C PE C+
Sbjct: 2314 VAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSC--PGSCP----SLSAPEGCESAC 2367
Query: 2336 GEGCVCSEGTILHRRHSALCIPEAKCAC 2363
EGCVC G +L C+P +C C
Sbjct: 2368 REGCVCDAGFVL---SGDTCVPVGQCGC 2392
Score = 85.9 bits (211), Expect = 5e-16
Identities = 100/388 (25%), Positives = 148/388 (38%), Gaps = 76/388 (19%)
Query: 2012 PPRCG---ILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS 2068
P CG + GL + G C P+ C + D +VT DG Y+LS
Sbjct: 3246 PASCGLGEVCGL-LPSGQHGCQPV--STAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAP 3302
Query: 2069 PDEMLTVHVLDCKSANLGHLNWPPFCLVMLN------MTHLAHQVTIDRFNRKVTVDLQP 2122
C LG N F + + N VT+ +N +T+ +
Sbjct: 3303 -----------CHGPPLGAEN---FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSAR- 3347
Query: 2123 VWPPVSRYG-------FRIEDTGHMYM------ILTPSDIQIQWLHSSGLMIVEASKTSK 2169
WP + F+++ H ++ + T S + + + S + + +
Sbjct: 3348 -WPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRL----RVPA 3402
Query: 2170 AQGHGLCGICDG---DAANDLTLKDGSV----VGGAEDPAPFLDSWQVPSSLTSVGQTRF 2222
A LCG+C D A+DL G VGGA+ + S PS T Q F
Sbjct: 3403 AYAGSLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECV-SKPCPSPCTPEQQESF 3461
Query: 2223 R-PDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVY 2277
PD+C + + + CH VPP + + + D VQ C A+ Y
Sbjct: 3462 GGPDACGVISAT-------DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATY 3514
Query: 2278 VAMCHKFHVCI-EWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQ-VL 2335
VA C + EWRR D+CPF C + S Y+ C +C P +C PE C+
Sbjct: 3515 VAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSC--PGSCP----SLSAPEGCESAC 3568
Query: 2336 GEGCVCSEGTILHRRHSALCIPEAKCAC 2363
EGCVC G +L C+P +C C
Sbjct: 3569 REGCVCDAGFVL---SGDTCVPVGQCGC 3593
Score = 84.7 bits (208), Expect = 1e-15
Identities = 105/415 (25%), Positives = 157/415 (37%), Gaps = 79/415 (19%)
Query: 2012 PPRCG---ILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS 2068
P CG + GL + G C P+ C + D +VT DG Y+LS
Sbjct: 4447 PASCGLGEVCGL-LPSGQHGCQPV--STAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAP 4503
Query: 2069 PDEMLTVHVLDCKSANLGHLNWPPFCLVMLN------MTHLAHQVTIDRFNRKVTVDLQP 2122
C LG N F + + N VT+ +N +T+ +
Sbjct: 4504 -----------CHGPPLGAEN---FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSAR- 4548
Query: 2123 VWPPVSRYG-------FRIEDTGHMYM------ILTPSDIQIQWLHSSGLMIVEASKTSK 2169
WP + F+++ H ++ + T S + + + S + + +
Sbjct: 4549 -WPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRL----RVPA 4603
Query: 2170 AQGHGLCGICDG---DAANDLTLKDGSV----VGGAEDPAPFLDSWQVPSSLTSVGQTRF 2222
A LCG+C D A+DL G VGGA+ + S PS T Q F
Sbjct: 4604 AYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECV-SKPCPSPCTPEQQESF 4662
Query: 2223 R-PDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVY 2277
PD+C + + + CH VPP + + + D VQ C A+ Y
Sbjct: 4663 GGPDACGVISAT-------DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATY 4715
Query: 2278 VAMCHKFHVCI-EWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQ-VL 2335
VA C + EWRR D+CP C + S Y+ C +C P +C PE C+
Sbjct: 4716 VAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSC--PVSCP----SLSAPEGCESAC 4769
Query: 2336 GEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQ 2390
EGCVC G +L C+P +C C G LGE + C+ +C+
Sbjct: 4770 REGCVCDAGFVL---SGDTCVPVGQCGCLHD-GRYYPLGEVFYPGPE--CERRCE 4818
Score = 84.3 bits (207), Expect = 2e-15
Identities = 86/371 (23%), Positives = 133/371 (35%), Gaps = 62/371 (16%)
Query: 848 GPCLSGCACPQGLLRHGDACF-LPEECPCTWKGKEY------FPGDQVMSPCHTCVCQRG 900
GPC+ GC C G + D C L C C W Y F D S C G
Sbjct: 1981 GPCVEGCQCDAGFVLSADRCVPLNNGCGC-WANGTYHEAGSEFWADGTCSQWCRCGPGGG 2039
Query: 901 SFQCTLHPCA--------------------STCTAYGDRHYRTFDGLPFDFVGACKVHLV 940
S CT C + C A+GD HY T DG F+F G C+ L
Sbjct: 2040 SLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFNFQGTCEYLLS 2099
Query: 941 -----KSTSDVSFSVIVENVNCYSSGMICRKFISINVGNSLIVFDD--------DSGNPS 987
+F+V V N + S + + +++ + N + D +
Sbjct: 2100 APCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVT 2159
Query: 988 PESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDL 1047
LD H + +V ++L +D + V ++ + G L GLCGN++
Sbjct: 2160 LPFQLDSLLHAH---LSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQ 2216
Query: 1048 KTINEMRT----PENLELTNPQEFGSSWAAVECPDTLDPRDMCVLNPLREPFAKKECSIL 1103
++++ P ++ Q G + CP P +E F + +
Sbjct: 2217 DPADDLKAVGGKPAGWQVGGAQGCGEC-VSKPCPSPCTPEQ-------QESFGGPDACGV 2268
Query: 1104 LSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-D 1159
+S CH +V ++ CL D C G C +V+ Y C G + +
Sbjct: 2269 ISATDGPLAPCHGLVPPAQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLRE 2326
Query: 1160 WRTPRLCPYDC 1170
WR P CP+ C
Sbjct: 2327 WRRPDFCPFQC 2337
Score = 83.6 bits (205), Expect = 3e-15
Identities = 131/574 (22%), Positives = 200/574 (34%), Gaps = 109/574 (18%)
Query: 1953 SAPALSIVEGLAEALATTTEAN-----TSTTCVPIAEQDCVRHI---------------- 1991
S P+LS EG A + + TCVP+ + C+
Sbjct: 3554 SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCD 3613
Query: 1992 ----CLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSF 2047
C EG + S P P G LG C + C+ S D +
Sbjct: 3614 SLCRCREGGEVSCEPSSCGPHETCRPSGGSLG---------CVAVGSTTCQAS--GDPHY 3662
Query: 2048 VTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQV 2107
TFDG +Y+L+Q+ +H N+ N ++ + +
Sbjct: 3663 TTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTL 3722
Query: 2108 TIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMI-VEASK 2166
+++ KVTV+ + PV +I + H ++ +D ++ + + V
Sbjct: 3723 RLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPG 3782
Query: 2167 TSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQ--VPSSLTSVGQTRFRP 2224
GLCG +GD +D +GS G A + F +SW+ VP S T P
Sbjct: 3783 NYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANE---FGNSWEEVVPDSPCLPPPT-CPP 3838
Query: 2225 DS--CATTD-CSPCLR----------MVSNRT--FSACHRFVPPESFCELWIRDTKY--- 2266
S C +D C P L ++S+ T S+CH+ V P+ + I D
Sbjct: 3839 GSAGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGG 3898
Query: 2267 -VQQPCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTAC-------EPPK 2317
+ C + YV+ C +E WR +CP C +S Y+ C C P
Sbjct: 3899 NLSILCSNIHAYVSACQAAGGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPL 3958
Query: 2318 TCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETW 2377
C DG EGC C G + + C+P +C C + GV E
Sbjct: 3959 QCPDG------------CAEGCQCDSGFLY---NGQACVPIQQCGCYHN-GV---YYEPE 3999
Query: 2378 NSSLSGCCQHQ--CQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCN 2435
+ L C+ Q C +V + C +P + L TKDP
Sbjct: 4000 QTVLIDNCRQQCTCHVGKVVVCQEHSC---KPGQVCQPSGGILSCVTKDP---------- 4046
Query: 2436 QTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCEC 2469
C G+ TCRP + C P+Y C
Sbjct: 4047 ---CHGV--TCRPQETCKEQGGQGVCLPNYEATC 4075
Score = 82.0 bits (201), Expect = 8e-15
Identities = 126/579 (21%), Positives = 197/579 (34%), Gaps = 119/579 (20%)
Query: 1953 SAPALSIVEGLAEALATTTEAN-----TSTTCVPIAEQDCVRHI---------------- 1991
S P+LS EG A + + TCVP+ + C+
Sbjct: 2353 SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCD 2412
Query: 1992 ----CLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSF 2047
C EG + S P P G LG C + C+ S D +
Sbjct: 2413 SLCRCREGGEVSCEPSSCGPHETCRPSGGSLG---------CVAVGSTTCQAS--GDPHY 2461
Query: 2048 VTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQV 2107
TFDG +Y+L+Q+ +H N+ N ++ + +
Sbjct: 2462 TTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTL 2521
Query: 2108 TIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMI-VEASK 2166
+++ KVTV+ + PV +I + H ++ +D ++ + + V
Sbjct: 2522 RLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPG 2581
Query: 2167 TSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQ--VPSSLTSVGQTRFRP 2224
GLCG +GD +D +GS G A + F +SW+ VP S P
Sbjct: 2582 NYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANE---FGNSWEEVVPDSPC------LPP 2632
Query: 2225 DSCA--------TTDCSPCLR----------MVSNRT--FSACHRFVPPESFCELWIRDT 2264
+C + +C P L ++S+ T S+CH+ V P+ + I D
Sbjct: 2633 PTCPPGSEGCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDL 2692
Query: 2265 KY----VQQPCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTAC------ 2313
+ C + YV+ C +E WR +CP C +S Y+ C C
Sbjct: 2693 CLGGGNLSILCSNIHAYVSACQAAGGQVEPWRNETFCPMECPQNSHYELCADTCSLGCSA 2752
Query: 2314 -EPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRA 2372
P C DG EGC C G + + C+P +C C + A
Sbjct: 2753 LSAPLQCPDG------------CAEGCQCDSGFLY---NGQACVPIQQCGCYHN----GA 2793
Query: 2373 LGETWNSSLSGCCQHQ--CQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGT 2430
E + L C+ Q C +V + C +P + L KDP
Sbjct: 2794 YYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSC---KPGQVCQPSGGILSCVNKDP----- 2845
Query: 2431 VCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCEC 2469
C G+ TCRP + C P+Y C
Sbjct: 2846 --------CHGV--TCRPQETCKEQGGQGVCLPNYEATC 2874
Score = 78.6 bits (192), Expect = 8e-14
Identities = 118/489 (24%), Positives = 165/489 (33%), Gaps = 103/489 (21%)
Query: 1983 AEQDCVRHICLEGQLIRVN--QSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCS 2040
A++ C R G +V Q CP G RC +V+ G C P C+ S
Sbjct: 816 ADELCQRRCTCNGATHQVTCRDKQSCPAGE---RC-----SVQNGLLGCYPDRFGTCQGS 867
Query: 2041 IFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNM 2100
D +V+FDG Y+L S + + P V++
Sbjct: 868 --GDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL----------------PAFRVLVEN 909
Query: 2101 THLAHQVTIDRFNRKVTVDLQPVWPPVSRY--GFRIEDTGHMYMILTPSDIQIQWLHSSG 2158
H Q + R V V+ + V V R G + D Y+ +D Q+Q
Sbjct: 910 EHRGSQTV--SYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGR 967
Query: 2159 LMIVEA---------------SKTSKAQGHGLCGIC---DGDAANDLTLKDGSVVGGAED 2200
+V +K + LCG+C +GD A+DL L+ G G A +
Sbjct: 968 DAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGG---GQAAN 1024
Query: 2201 PAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRT----------FSACHRF 2250
F +SWQ T G P C D ++ S F CH
Sbjct: 1025 ALAFGNSWQEE---TRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSK 1081
Query: 2251 VPPESFCELWIRDTKYVQ--------QPCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCS 2301
+ P+ +RD Y + C AL Y A C + WR + CP C
Sbjct: 1082 LDPQGA----VRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCP 1137
Query: 2302 SDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKC 2361
S Y+AC C P +C D + C EGCVC EG L C+P A C
Sbjct: 1138 PHSHYEACSYGC--PLSCGDLPVPGGCGSECH---EGCVCDEGFAL---SGESCLPLASC 1189
Query: 2362 ACTDSMGVPRALGETW-------------NSSLSGCCQHQCQAPDTIVPV--DLGCPSPR 2406
C G G+T+ L C C + P LGC +
Sbjct: 1190 GCV-HQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVG 1248
Query: 2407 PESCLRFGE 2415
+C G+
Sbjct: 1249 SSTCQASGD 1257
Score = 67.0 bits (162), Expect = 3e-10
Identities = 113/432 (26%), Positives = 159/432 (36%), Gaps = 65/432 (15%)
Query: 2029 CCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS-----PDEMLTVHVLDCKSA 2083
C P +E C ++ D + +FDG Y+L+ + + LT + K+
Sbjct: 1665 CLPNYEATCW--LWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQ 1722
Query: 2084 NLGHLNWPPFCLV-MLNMTHLAHQVTIDRFN-RKVTVDLQPVWPPVSRYGFRIEDTGHMY 2141
N G+ P V ++ + L ++I + KV V+ PVS RI T
Sbjct: 1723 NRGN---PAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGAS 1779
Query: 2142 MILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLKDGSVVGGAE 2199
L +D +Q + V+ + S G GLCG D + ND +G++
Sbjct: 1780 KALLVADFGLQVSYDWNWR-VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTL----- 1833
Query: 2200 DPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPC----------------LRMVSNRT 2243
AP + W S + G D C + C C L +
Sbjct: 1834 --APSIPIWG--GSWRAPGWDPLCWDECRGS-CPTCPEDRLEQYEGPGFCGPLAPGTGGP 1888
Query: 2244 FSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCIE-WRRSDYCPF 2298
F+ CH VPPESF + + D C AL YVA C V IE WR C
Sbjct: 1889 FTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEI 1948
Query: 2299 LCSSDSTYQACVTACEPPKTCQDGILGPL-DPEHCQ-VLGEGCVCSEGTILHRRHSALCI 2356
C +S Y+ C + C P +C PL P C+ EGC C G +L + C+
Sbjct: 1949 TCPENSHYEVCGSPC--PASCPSP--APLTTPAVCEGPCVEGCQCDAGFVL---SADRCV 2001
Query: 2357 P-EAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGE 2415
P C C + A E W G C C+ G P SC GE
Sbjct: 2002 PLNNGCGCWANGTYHEAGSEFW---ADGTCSQWCRCGP-----GGGSLVCTPASC-GLGE 2052
Query: 2416 VALLLPTKDPCC 2427
V LLP+ C
Sbjct: 2053 VCGLLPSGQHGC 2064
Score = 67.0 bits (162), Expect = 3e-10
Identities = 126/501 (25%), Positives = 178/501 (35%), Gaps = 85/501 (16%)
Query: 1977 TTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGIL---------GLAVRV--- 2024
T + Q C H+ G+++ + P P GIL G+ R
Sbjct: 2800 TVLIDNCRQQCTCHV---GKVVVCQEHSCKPGQVCQPSGGILSCVNKDPCHGVTCRPQET 2856
Query: 2025 -----GGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS-----PDEMLT 2074
G C P +E C ++ D + +FDG Y+L+ + + LT
Sbjct: 2857 CKEQGGQGVCLPNYEATCW--LWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLT 2914
Query: 2075 VHVLDCKSANLGHLNWPPFCLV-MLNMTHLAHQVTIDRFN-RKVTVDLQPVWPPVSRYGF 2132
+ K+ N G+ P V ++ + L ++I + KV V+ PVS
Sbjct: 2915 PFTVTTKNQNRGN---PAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADG 2971
Query: 2133 RIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLK 2190
RI T L +D +Q + V+ + S G GLCG D + ND
Sbjct: 2972 RISVTQGASKALLVADFGLQVSYDWNWR-VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFP 3030
Query: 2191 DGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPC--------------- 2235
+G++ AP + W S + G D C + C C
Sbjct: 3031 NGTL-------APSIPIWG--GSWRAPGWDPLCWDECRGS-CPTCPEDRLEQYEGPGFCG 3080
Query: 2236 -LRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCIE- 2289
L + F+ CH VPPESF + + D C AL YVA C V IE
Sbjct: 3081 PLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIED 3140
Query: 2290 WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPL-DPEHCQ-VLGEGCVCSEGTIL 2347
WR C C +S Y+ C C P +C PL P C+ EGC C G +L
Sbjct: 3141 WRAQVGCEITCPENSHYEVCGPPC--PASCPSP--APLTTPAVCEGPCVEGCQCDAGFVL 3196
Query: 2348 HRRHSALCIP-EAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPR 2406
+ C+P C C + A E W G C C+ G
Sbjct: 3197 ---SADRCVPLNNGCGCWANGTYHEAGSEFW---ADGTCSQWCRCGP-----GGGSLVCT 3245
Query: 2407 PESCLRFGEVALLLPTKDPCC 2427
P SC GEV LLP+ C
Sbjct: 3246 PASC-GLGEVCGLLPSGQHGC 3265
Score = 65.9 bits (159), Expect = 6e-10
Identities = 123/499 (24%), Positives = 174/499 (34%), Gaps = 81/499 (16%)
Query: 1977 TTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVR--VGGDRCCPLWE 2034
T + Q C H+ G+++ + P P GIL + G C P
Sbjct: 4001 TVLIDNCRQQCTCHV---GKVVVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQET 4057
Query: 2035 CA-------------CRCSIFPDLSFVTFDGSHVALFKEAIYILSQS-----PDEMLTVH 2076
C C ++ D + +FDG Y+L+ + + LT
Sbjct: 4058 CKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPF 4117
Query: 2077 VLDCKSANLGHLNWPPFCLV-MLNMTHLAHQVTIDRFN-RKVTVDLQPVWPPVSRYGFRI 2134
+ K+ N G+ P V ++ + L ++I + KV V+ PVS RI
Sbjct: 4118 TVTTKNQNRGN---PAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRI 4174
Query: 2135 EDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLKDG 2192
L +D +Q + V+ + S G GLCG D + ND +G
Sbjct: 4175 SVAQGASKALLVADFGLQVSYDWNWR-VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNG 4233
Query: 2193 SVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPC----------------L 2236
++ AP + W S + G D C + C C L
Sbjct: 4234 TL-------APSIPIWG--GSWRAPGWDPLCWDECRGS-CPTCPEDRLEQYEGPGFCGPL 4283
Query: 2237 RMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCIE-WR 2291
+ F+ CH VPPESF + + D C AL YVA C V IE WR
Sbjct: 4284 SSGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWR 4343
Query: 2292 RSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPL-DPEHCQ-VLGEGCVCSEGTILHR 2349
C C +S Y+ C C P +C PL P C+ EGC C G +L
Sbjct: 4344 AQVGCEITCPENSHYEVCGPPC--PASCPSP--APLTTPAVCEGPCVEGCQCDAGFVL-- 4397
Query: 2350 RHSALCIP-EAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPE 2408
+ C+P C C + A E W G C C+ G P
Sbjct: 4398 -SADRCVPLNNGCGCWANGTYHEAGSEFW---ADGTCSQWCRCGP-----GGGSLVCTPA 4448
Query: 2409 SCLRFGEVALLLPTKDPCC 2427
SC GEV LLP+ C
Sbjct: 4449 SC-GLGEVCGLLPSGQHGC 4466
Score = 32.7 bits (73), Expect = 5.3
Identities = 26/96 (27%), Positives = 33/96 (34%), Gaps = 17/96 (17%)
Query: 811 CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLS--VSARGPCLSGCACPQGLLRHGDACF 868
CPA + C+ RTC+ LS C GC C L C
Sbjct: 5121 CPAHSHYSICT-----------RTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCI 5169
Query: 869 LPEECPCTWKGKEYFP--GDQVMSPC-HTCVCQRGS 901
++C CT G+ Y P + S C C C S
Sbjct: 5170 PVQDCGCTHNGR-YLPVNSSLLTSDCSERCSCSSSS 5204
>gi|239757282 PREDICTED: similar to Fc fragment of IgG binding protein
[Homo sapiens]
Length = 1403
Score = 297 bits (761), Expect = 9e-80
Identities = 305/1178 (25%), Positives = 452/1178 (38%), Gaps = 205/1178 (17%)
Query: 73 PERDSICRAWGQHHVETFDGLYYYLSGKGSYTL-----VGRHEPEGQSFSIQVHNDPQCG 127
P ++ C WG H +FDG + G +Y L +G F++ N+ + G
Sbjct: 69 PNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLTPFTVTTKNENR-G 127
Query: 128 SSPYTCSRAVSLFFVGEQ-EIHLAK--EVTHGGMRVQLPHVMGSARLQ--QLAGYVIVRH 182
+ + R V++ +G IH + +V G+ LP + R+ Q A ++
Sbjct: 128 NPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVA 187
Query: 183 QSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ 242
+++D V + + G GLCGN + +P +D V +G L + + SW+
Sbjct: 188 DFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWR 247
Query: 243 EQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEAL-----LRP----PFDACHAYVS 293
AP P L C P + EQ E L P PF CHA+V
Sbjct: 248 --APGWDP------LCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVP 299
Query: 294 PLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFT 353
P F C D+C GD C+ALA Y AC AG ++ WR Q+ C + C E +
Sbjct: 300 PESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVVIEDWRAQV-GCEITCPENSH- 357
Query: 354 YNECIACCPASC---HPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE-CPCEFHGTL 409
Y C CPASC P + E CV+GC C G + CV C C +GT
Sbjct: 358 YEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTY 417
Query: 410 YPPGSVVKED--CNT-CTC--TSGKWECSTAVC--------------------PAECSVT 444
+ GS D C+ C C G C+ A C AEC
Sbjct: 418 HEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAW 477
Query: 445 GDIHFTTFDGRRYTFPATCQYILA-----KSRSSGTFTVTLQNAPCGLNQDGACVQSVSV 499
GD H+ T DG R+ F TC+Y+L+ + FTVT+ N G +Q + +SV++
Sbjct: 478 GDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTL 536
Query: 500 ILHQDPRRQVTLTQAGD-VLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDR 558
++ +TL+ L D + P+ D+ LS + V T G+ + +D
Sbjct: 537 QIY---NHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDG 593
Query: 559 EGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA--CSP 616
+ + L+V + GLCG +N + DD + G P W+ A C
Sbjct: 594 DSF-VRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQGCGE 644
Query: 617 LVSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDACRC-GQ 673
VS PC Q + AC V+ T APC + P YF+ C DAC+ G
Sbjct: 645 CVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGH 704
Query: 674 P-CLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEA 732
P LC +A Y C+ G + R C L C A Y C C +C L++PE
Sbjct: 705 PGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEG 764
Query: 733 CGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGH 792
C C EGC C D D CVP QC C G YP G+ P
Sbjct: 765 C---------ESACREGCVC--DAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPG--- 810
Query: 793 CHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLS 852
C+ R P G V TC++
Sbjct: 811 -------PECERRCECG--PGGHV-----------------TCQE--------------- 829
Query: 853 GCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPCAST 912
G AC EEC + + CH C R
Sbjct: 830 -----------GAACGPHEECRL----------EDGVQACHATGCGR------------- 855
Query: 913 CTAYGDRHYRTFDGLPFDFVGACKVHLVK----STSDVSFSVIVENVNCYSSGMICR--- 965
C A G HY T DG +D G+C L + D FS+++E ++G + R
Sbjct: 856 CLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEK---NAAGDLQRLLV 912
Query: 966 ----KFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWD 1021
+ +S+ G + V + P + E +V + + LL+D
Sbjct: 913 TVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGR-------NMVLQTTKGLRLLFD 965
Query: 1022 QRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSW----AAVECP 1077
+ + ++G+L GLCGNF+ ++ P ++ + FG++W ++ C
Sbjct: 966 GDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCG 1025
Query: 1078 DTLDPR--DMCVLNPLREPFAKKECSILLSE--VFEICHPVVDVTWFYSNCLTDTCGCSQ 1133
+ P+ +C+ + + C L + F C V+ + ++ C+ D C+Q
Sbjct: 1026 EGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDL--CAQ 1083
Query: 1134 GGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1170
GD C S++AY C GVAV WRT CP C
Sbjct: 1084 KGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHC 1121
Score = 254 bits (649), Expect = 9e-67
Identities = 233/821 (28%), Positives = 317/821 (38%), Gaps = 90/821 (10%)
Query: 44 GGECV-HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGS 102
GG V PA C P Q + P + C+AWG H T DG + G
Sbjct: 440 GGSLVCTPASCGLGEVCGLLPSGQ--HGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCE 497
Query: 103 YTLVGR-HEPE--GQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQ---EIHLAKEVTHG 156
Y L H P ++F++ V N+ + GS + +R+V+L +++
Sbjct: 498 YLLSAPCHGPPLGAENFTVTVANEHR-GSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD 556
Query: 157 GMRVQLPHVMGSARLQQLAGY-VIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNN 215
G+ V LP + S L+G V+V S +LA+DG S V +++ GLCGN
Sbjct: 557 GVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNY 616
Query: 216 NADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQ--GV 273
N DP DDL GK V E P P T P Q++ G GV
Sbjct: 617 NQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCT------PEQQESFGGPDACGV 670
Query: 274 YEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 333
+ L P CH V P + C D CQ G C A+A Y AC AG L
Sbjct: 671 ISATDGPLAP----CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQL 726
Query: 334 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDG 393
WR C + C + Y C CP SC ++ E AC +GC C G +
Sbjct: 727 GEWRRP-DFCPLQCPAHSH-YELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGD 784
Query: 394 GCVAPAECPCEFHGTLYP------PGSVVKEDCNT-------------------CTCTSG 428
CV +C C G YP PG + C C G
Sbjct: 785 TCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDG 844
Query: 429 KWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAK----SRSSGTFTVTLQNAP 484
C C C G IH+ T DGR Y +C Y+LA+ F++ L+
Sbjct: 845 VQACHATGC-GRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNA 903
Query: 485 CGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFL 544
G + +L + V+L Q V + + +P ++ L
Sbjct: 904 AG---------DLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVL 954
Query: 545 RVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLF 604
+ T G+R+L+D + L + + + GLCG FNGN DDF+ P G S+ + F
Sbjct: 955 Q--TTKGLRLLFDGDA-HLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETF 1011
Query: 605 GNSWKTLSACSPLVSGSPLDPCDVHL--QAASY-SVQACSVLTGEM--FAPCSAFLSPVP 659
G +W+ + G C V L + A Y S +AC L FA C A LSP
Sbjct: 1012 GAAWRVPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSE 1071
Query: 660 YFEQCRRDAC--RCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCV 717
YF QC D C + + LC +LA Y C+ G+ V C L C A YS C
Sbjct: 1072 YFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICT 1131
Query: 718 APCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQG 777
C +C L+ C C EGC C D +L +Q +C+P C C G
Sbjct: 1132 RTCQGSCAALSGLTGC---------TTRCFEGCEC-DDRFLLSQG-VCIPVQDCGCTHNG 1180
Query: 778 VDYPPGDSDIPS--LGHCHCKDGVMSCDSRAPAAACPAGQV 816
P S + S C C S AA CP G+V
Sbjct: 1181 RYLPVNSSLLTSDCSERCSCSS---SSGLTCQAAGCPPGRV 1218
Score = 161 bits (407), Expect = 1e-38
Identities = 154/588 (26%), Positives = 227/588 (38%), Gaps = 47/588 (7%)
Query: 30 RAKCAPSYLFSCFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVET 89
R +C P +C G C +CR + Q + G R C A G H T
Sbjct: 816 RCECGPGGHVTCQEGAACGPHE--ECRLEDGV----QACHATGCGR---CLANGGIHYIT 866
Query: 90 FDGLYYYLSGKGSYTL--VGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEI 147
DG Y L G SY L V +P + FSI + + L V Q +
Sbjct: 867 LDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRL-------LVTVAGQVV 919
Query: 148 HLAK--EVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELL 205
LA+ +VT G V LP +G R+ ++++ L +DG + + + +
Sbjct: 920 SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFR 979
Query: 206 GWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQ 265
G GLCGN N + DD V +G V F +W+ ++ G P CL +
Sbjct: 980 GRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEGCGPQGCPVCLAE 1039
Query: 266 NPGTMQGVYEQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYA 323
+ E C L P PF C A +SP + C DLC GD A CR+LA Y
Sbjct: 1040 ETAPYES-NEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYT 1098
Query: 324 RACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCY 383
AC AG ++ WRT C +HC + Y+ C C SC + C +GC
Sbjct: 1099 AACQAAGVAVKPWRTD-SFCPLHCPAHSH-YSICTRTCQGSCAALSGLTGCTTRCFEGCE 1156
Query: 384 CPNGLIFEDGGCVAPAECPCEFHGTLYP-PGSVVKEDCN-TCTCTSGK-WECSTAVCP-- 438
C + + G C+ +C C +G P S++ DC+ C+C+S C A CP
Sbjct: 1157 CDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPG 1216
Query: 439 ------AE----------CSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQN 482
AE C ++ + TTFDG R + Y L+ T+
Sbjct: 1217 RVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYR 1276
Query: 483 APCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSV 542
+ ++V + VTLT V + +P + + R
Sbjct: 1277 VVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDG 1336
Query: 543 FLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDF 590
L VR GV+V G ++ + V G CG F+G+ +D+
Sbjct: 1337 SLLVRQKAGVQVWLGANG-KVAVIVSNDHAGKLCGACGNFDGDQTNDW 1383
Score = 94.0 bits (232), Expect = 2e-18
Identities = 117/501 (23%), Positives = 187/501 (37%), Gaps = 85/501 (16%)
Query: 1953 SAPALSIVEGLAEALATTTEAN-----TSTTCVPIAEQDCVRHICLEGQLIRVNQSQHC- 2006
S P+LS EG A + + TCVP+ + C+ +G+ + + +
Sbjct: 755 SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLH----DGRYYPLGEVFYPG 810
Query: 2007 PQGAAPPRCGILGLAVRVGGDRCCPLWEC-------AC------RCSIFPDLSFVTFDGS 2053
P+ CG G G C P EC AC RC + ++T DG
Sbjct: 811 PECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGR 870
Query: 2054 HVALFKEAIYILSQ-----SPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVT 2108
L Y+L+Q DE ++ + + +L L + +A QV
Sbjct: 871 VYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRL-----------LVTVAGQVV 919
Query: 2109 IDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTS 2168
++VTVD + V PV+ R+ G ++ T +++ + + L++ S S
Sbjct: 920 SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLM---SIPS 976
Query: 2169 KAQGH--GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDS 2226
+G GLCG +G+ ++D L +GS E F +W+VP S G+
Sbjct: 977 PFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVET---FGAAWRVPGSSKGCGE------G 1027
Query: 2227 CATTDCSPCL--RMVSNRTFSACHRFVPPE---SFCELWIRDTKYVQQP----------- 2270
C C CL + AC + P+ + C+ + ++Y +Q
Sbjct: 1028 CGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDK 1087
Query: 2271 ---CVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGP 2326
C +L Y A C V ++ WR +CP C + S Y C C+ G+ G
Sbjct: 1088 AFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTG- 1146
Query: 2327 LDPEHCQV-LGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCC 2385
C EGC C + +L + +CIP C CT + S S C
Sbjct: 1147 -----CTTRCFEGCECDDRFLLSQ---GVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERC 1198
Query: 2386 QHQCQAPDTIVPVDLGCPSPR 2406
C + + GCP R
Sbjct: 1199 --SCSSSSGLTCQAAGCPPGR 1217
Score = 84.7 bits (208), Expect = 1e-15
Identities = 105/415 (25%), Positives = 157/415 (37%), Gaps = 79/415 (19%)
Query: 2012 PPRCG---ILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS 2068
P CG + GL + G C P+ C + D +VT DG Y+LS
Sbjct: 447 PASCGLGEVCGL-LPSGQHGCQPV--STAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAP 503
Query: 2069 PDEMLTVHVLDCKSANLGHLNWPPFCLVMLN------MTHLAHQVTIDRFNRKVTVDLQP 2122
C LG N F + + N VT+ +N +T+ +
Sbjct: 504 -----------CHGPPLGAEN---FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSAR- 548
Query: 2123 VWPPVSRYG-------FRIEDTGHMYM------ILTPSDIQIQWLHSSGLMIVEASKTSK 2169
WP + F+++ H ++ + T S + + + S + + +
Sbjct: 549 -WPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRL----RVPA 603
Query: 2170 AQGHGLCGICDG---DAANDLTLKDGSV----VGGAEDPAPFLDSWQVPSSLTSVGQTRF 2222
A LCG+C D A+DL G VGGA+ + S PS T Q F
Sbjct: 604 AYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECV-SKPCPSPCTPEQQESF 662
Query: 2223 R-PDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVY 2277
PD+C + + + CH VPP + + + D VQ C A+ Y
Sbjct: 663 GGPDACGVISAT-------DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATY 715
Query: 2278 VAMCHKFHVCI-EWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQ-VL 2335
VA C + EWRR D+CP C + S Y+ C +C P +C PE C+
Sbjct: 716 VAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSC--PVSCP----SLSAPEGCESAC 769
Query: 2336 GEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQ 2390
EGCVC G +L C+P +C C G LGE + C+ +C+
Sbjct: 770 REGCVCDAGFVL---SGDTCVPVGQCGCLHD-GRYYPLGEVFYPGPE--CERRCE 818
Score = 80.9 bits (198), Expect = 2e-14
Identities = 77/315 (24%), Positives = 117/315 (37%), Gaps = 43/315 (13%)
Query: 891 PCHTCVC-------QRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHL---- 939
PCH C ++G L +TC +GD HY +FDG FDF G C L
Sbjct: 46 PCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTG 105
Query: 940 ---VKSTSDVSFSVIVENVNCYSSGMICRKFISI-NVGNSLIVFDDDSG--------NPS 987
V + F+V +N N + + + +++ +G ++ + D+ G
Sbjct: 106 CLGVSTQGLTPFTVTTKNENRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTAL 165
Query: 988 PESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDL 1047
P S D + V + F + + +D V V + G + GLCGN D
Sbjct: 166 PVSVADGRISVAQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDR 222
Query: 1048 KTINEMRTPENLELTNPQEFGSSWAAV--------ECPDTLDPRDMCVLNPLREPFAKKE 1099
N+ P + +G SW A EC + C + L +
Sbjct: 223 NPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSC---PTCPEDRLEQYEGPGF 279
Query: 1100 CSILLSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGV 1156
C L F CH V F+ C+ D C GGD + C ++++Y C GV
Sbjct: 280 CGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDHDILCKALASYVAACQAAGV 337
Query: 1157 AV-DWRTPRLCPYDC 1170
+ DWR C C
Sbjct: 338 VIEDWRAQVGCEITC 352
Score = 64.3 bits (155), Expect = 2e-09
Identities = 112/432 (25%), Positives = 157/432 (36%), Gaps = 65/432 (15%)
Query: 2029 CCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS-----PDEMLTVHVLDCKSA 2083
C P +E C ++ D + +FDG Y+L+ + + LT + K+
Sbjct: 67 CLPNYEATCW--LWGDPHYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLTPFTVTTKNE 124
Query: 2084 NLGHLNWPPFCLV-MLNMTHLAHQVTIDRFN-RKVTVDLQPVWPPVSRYGFRIEDTGHMY 2141
N G+ P V ++ + L ++I + KV V+ PVS RI
Sbjct: 125 NRGN---PAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGAS 181
Query: 2142 MILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLKDGSVVGGAE 2199
L +D +Q + V+ + S G GLCG D + ND +G++
Sbjct: 182 KALLVADFGLQVSYDWNWR-VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTL----- 235
Query: 2200 DPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPC----------------LRMVSNRT 2243
AP + W S + G D C + C C L +
Sbjct: 236 --APSIPIWG--GSWRAPGWDPLCWDECRGS-CPTCPEDRLEQYEGPGFCGPLAPGTGGP 290
Query: 2244 FSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCIE-WRRSDYCPF 2298
F+ CH VPPESF + + D C AL YVA C V IE WR C
Sbjct: 291 FTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVVIEDWRAQVGCEI 350
Query: 2299 LCSSDSTYQACVTACEPPKTCQDGILGPL-DPEHCQ-VLGEGCVCSEGTILHRRHSALCI 2356
C +S Y+ C C P +C PL P C+ EGC C G +L + C+
Sbjct: 351 TCPENSHYEVCGPPC--PASCPSP--APLTTPAVCEGPCVEGCQCDAGFVL---SADRCV 403
Query: 2357 P-EAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGE 2415
P C C + A E W G C C+ G P SC GE
Sbjct: 404 PLNNGCGCWANGTYHEAGSEFW---ADGTCSQWCRCGP-----GGGSLVCTPASC-GLGE 454
Query: 2416 VALLLPTKDPCC 2427
V LLP+ C
Sbjct: 455 VCGLLPSGQHGC 466
Score = 32.7 bits (73), Expect = 5.3
Identities = 26/96 (27%), Positives = 33/96 (34%), Gaps = 17/96 (17%)
Query: 811 CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLS--VSARGPCLSGCACPQGLLRHGDACF 868
CPA + C+ RTC+ LS C GC C L C
Sbjct: 1121 CPAHSHYSICT-----------RTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCI 1169
Query: 869 LPEECPCTWKGKEYFP--GDQVMSPC-HTCVCQRGS 901
++C CT G+ Y P + S C C C S
Sbjct: 1170 PVQDCGCTHNGR-YLPVNSSLLTSDCSERCSCSSSS 1204
>gi|239757286 PREDICTED: similar to Fc fragment of IgG binding protein
[Homo sapiens]
Length = 1472
Score = 280 bits (716), Expect = 1e-74
Identities = 247/825 (29%), Positives = 336/825 (40%), Gaps = 105/825 (12%)
Query: 60 ATGPRCQMVYNAG---PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQ-- 114
A G RCQ+V E ++CRA G H TFDG Y + G SYT+V +
Sbjct: 511 AAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLP 570
Query: 115 SFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHL---AKEVTHG--------GMRVQLP 163
+FS++ N+ + SR VS +VG + + +T G R +LP
Sbjct: 571 AFSVEAKNE-------HRGSRRVS--YVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLP 621
Query: 164 HVMGSARLQ--QLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKD 221
+ RL+ Q +V + +D + + + GLCGN N DP D
Sbjct: 622 VSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPAD 681
Query: 222 DLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEA-- 279
D +T G L D VEF SW+ + L C P G + E
Sbjct: 682 DFLTPDGALAPDAVEFASSWKLDDGDY--------LCEDGCQNNCPACTPGQAQHYEGDR 733
Query: 280 ------LLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 333
L PF CH + P PF C DLC G+ + CR L+ YA+AC + G +
Sbjct: 734 LCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISV 793
Query: 334 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVD-SEIACVDGCYCPNGLIFED 392
WR+ C + C + Y C CP SC+ A+ + S CV+GC C G +
Sbjct: 794 GDWRSP-ANCPLSCPANS-RYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASG 851
Query: 393 GGCVAPAECPCEFHGTLYPPGSVVKED--C-NTCTCTSGKWECS---TAVCPA--ECSV- 443
G CV + C C F G PG V D C CTC + + CPA CSV
Sbjct: 852 GACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQ 911
Query: 444 ----------------TGDIHFTTFDGRRYTFPATCQYILAKSRSSG----TFTVTLQNA 483
+GD H+ +FDGRR+ F TC Y+L S F V ++N
Sbjct: 912 NGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENE 971
Query: 484 PCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIP-PYTDDAFEIRRLSSV 542
G +Q + ++V V + + V G VL+ D + +P D ++ R
Sbjct: 972 HRG-SQTVSYTRAVRVEA-RGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRD 1029
Query: 543 FLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQ 602
+ VRT+ G+ V YD R+ +V + E GLCG FNG+ DD G +
Sbjct: 1030 AV-VRTDFGLTVTYDWNA-RVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANAL 1087
Query: 603 LFGNSW--KTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEM--FAPCSAFLSPV 658
FGNSW +T C G D + S C +L F C + L P
Sbjct: 1088 AFGNSWQEETRPGCGATEPGD-CPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQ 1146
Query: 659 PYFEQCRRDACRC-GQP-CLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPC 716
C D C GQ LC LA YA C+ G V C LSC Y C
Sbjct: 1147 GAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEAC 1206
Query: 717 VAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQ 776
C +C DL P CG EC EGC C D + C+P C C Q
Sbjct: 1207 SYGCPLSCGDLPVPGGCG---------SECHEGCVC--DEGFALSGESCLPLASCGCVHQ 1255
Query: 777 GVDYPPGDSDIPSLG---HCHCKD-GVMSCDSRA--PAAAC-PAG 814
G +PPG + P G CHC++ G++SC+S + P AC P+G
Sbjct: 1256 GTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSG 1300
Score = 162 bits (409), Expect = 6e-39
Identities = 130/461 (28%), Positives = 184/461 (39%), Gaps = 49/461 (10%)
Query: 49 HPAFCDCRRFNATGPRCQM---VYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTL 105
H C ++ G RC + + P+R C+ G H +FDG + G +Y L
Sbjct: 892 HQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLL 951
Query: 106 VGRHEPEGQ--SFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLP 163
VG +F + V N+ + GS + +RAV V + + +A + G +V +
Sbjct: 952 VGSCGQNAALPAFRVLVENEHR-GSQTVSYTRAVR---VEARGVKVAVRREYPG-QVLVD 1006
Query: 164 HVMGSARLQQLAGYV---------IVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGN 214
V+ Q G V +VR T+ +D + V K+ GLCGN
Sbjct: 1007 DVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGN 1066
Query: 215 NNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVY 274
N DP DDL G + + F +SWQE+ PG + P L
Sbjct: 1067 FNGDPADDLALRGGGQAANALAFGNSWQEETR---PGCGATEPGDCPKLDSLVAQQLQSK 1123
Query: 275 EQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRP 332
+C L P PF CH+ + P C D C G C ALA YA AC AG
Sbjct: 1124 NECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGAT 1183
Query: 333 LQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFED 392
+ WR++ C + C + Y C CP SC C +GC C G
Sbjct: 1184 VHPWRSE-ELCPLSCPPHSH-YEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSG 1241
Query: 393 GGCVAPAECPCEFHGTLYPPGSVVKED--CNT-CTCTSGKW-ECSTAVC----------- 437
C+ A C C GT +PPG C++ C C G C ++ C
Sbjct: 1242 ESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGG 1301
Query: 438 --------PAECSVTGDIHFTTFDGRRYTFPATCQYILAKS 470
+ C +GD H+TTFDGRR+ F TC Y+LA++
Sbjct: 1302 SLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQT 1342
Score = 115 bits (287), Expect = 8e-25
Identities = 111/421 (26%), Positives = 162/421 (38%), Gaps = 61/421 (14%)
Query: 798 GVMSCDSRAPA---AACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGC 854
G+ D R+PA +CPA + C + +C + S R PC+ GC
Sbjct: 790 GISVGDWRSPANCPLSCPANSRYELCGP-------ACPTSCNGAAAPSNCSGR-PCVEGC 841
Query: 855 ACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSP--C-HTCVCQRGSFQCTLHPCAS 911
C G + G AC C CT++G + PG +V + C C C + Q T S
Sbjct: 842 VCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQS 901
Query: 912 ----------------------TCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD---- 945
TC GD HY +FDG FDF+G C LV S
Sbjct: 902 CPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL 961
Query: 946 VSFSVIVENVNCYSSGMICRKFISINVGNSLI---------VFDDDSGNPSPESFLDDKQ 996
+F V+VEN + S + + + + + V DD P D
Sbjct: 962 PAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADG-- 1019
Query: 997 EVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTP 1056
+V +R G +V +T+ +D V + + L GLCGNF+ +++
Sbjct: 1020 QVQVFRQGRDAVVR-TDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALR 1078
Query: 1057 ENLELTNPQEFGSSWAAVECP--DTLDPRDMCVLNPL--REPFAKKECSILLSE--VFEI 1110
+ N FG+SW P +P D L+ L ++ +K EC IL F
Sbjct: 1079 GGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRE 1138
Query: 1111 CHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYD 1169
CH +D +C+ D C G C +++ YA C G V WR+ LCP
Sbjct: 1139 CHSKLDPQGAVRDCVYDR--CLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLS 1196
Query: 1170 C 1170
C
Sbjct: 1197 C 1197
Score = 98.6 bits (244), Expect = 8e-20
Identities = 82/297 (27%), Positives = 126/297 (42%), Gaps = 27/297 (9%)
Query: 895 CVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD----VSFSV 950
C G C A C A GD HY TFDG +D +G C +V+ S+ +FSV
Sbjct: 516 CQVVGGKAGCVAESTA-VCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSV 574
Query: 951 IVENVN------CYSSGMICRKF---ISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTW 1001
+N + Y + R + +S+ G V D+ + P S + + V+
Sbjct: 575 EAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQS 634
Query: 1002 RVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLEL 1061
+ F +T WD + + + A ++Q Q+ GLCGN++ ++ TP+
Sbjct: 635 GPRAVVELVFGLV-VTYDWDCQLALSLPA--RFQDQVCGLCGNYNGDPADDFLTPDGALA 691
Query: 1062 TNPQEFGSSWAAVE----CPDTLDPR-DMCVLNPLREPFAKKECSIL--LSEVFEICHPV 1114
+ EF SSW + C D C + + C +L L F +CH
Sbjct: 692 PDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDT 751
Query: 1115 VDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1170
+D F C+ D C GG+ C +SAYA C + G++V DWR+P CP C
Sbjct: 752 LDPRPFLEQCVYDL--CVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSC 806
Score = 91.3 bits (225), Expect = 1e-17
Identities = 115/456 (25%), Positives = 171/456 (37%), Gaps = 78/456 (17%)
Query: 1962 GLAEALATTTEANTSTTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLA 2021
GLA+A+ T A+ T + E C C GQ RC +
Sbjct: 480 GLAKAIGYATAADCGRTVLSPVEPSCEGMQCAAGQ-----------------RCQV---- 518
Query: 2022 VRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQ--SPDEMLTVHVLD 2079
VGG C + E C D + TFDG + Y + + S D+ L ++
Sbjct: 519 --VGGKAGC-VAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVE 575
Query: 2080 CKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRK-VTVDLQPVWPPVS--RYGFRIED 2136
K+ + G LV + +H V++ R V VD Q PVS R+
Sbjct: 576 AKNEHRGSRRVSYVGLVTVRA--YSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQ 633
Query: 2137 TGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVG 2196
+G ++ + + + L + ++ Q GLCG +GD A+D DG++
Sbjct: 634 SGPRAVVELVFGLVVTYDWDCQLALSLPARFQD-QVCGLCGNYNGDPADDFLTPDGAL-- 690
Query: 2197 GAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCL----------RMVSNRT--- 2243
A D F SW++ D C +C C R+ T
Sbjct: 691 -APDAVEFASSWKLDDG------DYLCEDGCQN-NCPACTPGQAQHYEGDRLCGMLTKLD 742
Query: 2244 --FSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCI-EWRRSDYC 2296
F+ CH + P F E + D V C L+ Y C + + + +WR C
Sbjct: 743 GPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANC 802
Query: 2297 PFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHC--QVLGEGCVCSEGTILHRRHSAL 2354
P C ++S Y+ C AC P +C G P +C + EGCVC G +
Sbjct: 803 PLSCPANSRYELCGPAC--PTSCN----GAAAPSNCSGRPCVEGCVCLPGFV---ASGGA 853
Query: 2355 CIPEAKCACTDSMGVPRALG-ETWNSSLSGCCQHQC 2389
C+P + C CT G+ A G E W L CQ +C
Sbjct: 854 CVPASSCGCT-FQGLQLAPGQEVWADEL---CQRRC 885
Score = 78.6 bits (192), Expect = 8e-14
Identities = 118/489 (24%), Positives = 165/489 (33%), Gaps = 103/489 (21%)
Query: 1983 AEQDCVRHICLEGQLIRVN--QSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCS 2040
A++ C R G +V Q CP G RC +V+ G C P C+ S
Sbjct: 877 ADELCQRRCTCNGATHQVTCRDKQSCPAGE---RC-----SVQNGLLGCYPDRFGTCQGS 928
Query: 2041 IFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNM 2100
D +V+FDG Y+L S + + P V++
Sbjct: 929 --GDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL----------------PAFRVLVEN 970
Query: 2101 THLAHQVTIDRFNRKVTVDLQPVWPPVSRY--GFRIEDTGHMYMILTPSDIQIQWLHSSG 2158
H Q + R V V+ + V V R G + D Y+ +D Q+Q
Sbjct: 971 EHRGSQTV--SYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGR 1028
Query: 2159 LMIVEA---------------SKTSKAQGHGLCGIC---DGDAANDLTLKDGSVVGGAED 2200
+V +K + LCG+C +GD A+DL L+ G G A +
Sbjct: 1029 DAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGG---GQAAN 1085
Query: 2201 PAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRT----------FSACHRF 2250
F +SWQ T G P C D ++ S F CH
Sbjct: 1086 ALAFGNSWQEE---TRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSK 1142
Query: 2251 VPPESFCELWIRDTKYVQ--------QPCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCS 2301
+ P+ +RD Y + C AL Y A C + WR + CP C
Sbjct: 1143 LDPQGA----VRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCP 1198
Query: 2302 SDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKC 2361
S Y+AC C P +C D + C EGCVC EG L C+P A C
Sbjct: 1199 PHSHYEACSYGC--PLSCGDLPVPGGCGSECH---EGCVCDEGFAL---SGESCLPLASC 1250
Query: 2362 ACTDSMGVPRALGETW-------------NSSLSGCCQHQCQAPDTIVPV--DLGCPSPR 2406
C G G+T+ L C C + P LGC +
Sbjct: 1251 GCV-HQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVG 1309
Query: 2407 PESCLRFGE 2415
+C G+
Sbjct: 1310 SSTCQASGD 1318
Score = 68.9 bits (167), Expect = 7e-11
Identities = 47/156 (30%), Positives = 66/156 (42%), Gaps = 35/156 (22%)
Query: 850 CLSGCACPQGLLRHGDACFLPEECPCTWKG------KEYFPGDQVMSPCHTCVCQRGSF- 902
C GC C +G G++C C C +G + ++PG S CH CQ G
Sbjct: 1227 CHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCH---CQEGGLV 1283
Query: 903 QCTLHPC-------------------ASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKST 943
C C +STC A GD HY TFDG FDF+G C V+++ T
Sbjct: 1284 SCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTC-VYVLAQT 1342
Query: 944 SDV-----SFSVIVENVNCYSSGMICRKFISINVGN 974
F+V+ ENV + + + I++ V N
Sbjct: 1343 CGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVAN 1378
Score = 32.7 bits (73), Expect = 5.3
Identities = 22/77 (28%), Positives = 30/77 (38%), Gaps = 11/77 (14%)
Query: 1992 CLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFD 2051
C EG L+ S P A P G LG C + C+ S D + TFD
Sbjct: 1277 CQEGGLVSCESSSCGPHEACQPSGGSLG---------CVAVGSSTCQAS--GDPHYTTFD 1325
Query: 2052 GSHVALFKEAIYILSQS 2068
G +Y+L+Q+
Sbjct: 1326 GRRFDFMGTCVYVLAQT 1342
>gi|239755776 PREDICTED: similar to Mucin-19 [Homo sapiens]
Length = 1950
Score = 268 bits (686), Expect = 4e-71
Identities = 171/552 (30%), Positives = 262/552 (47%), Gaps = 43/552 (7%)
Query: 301 CTSDLCQSMGDVATWCRALAEYARACAQAGR-PLQGWRTQLRQC--TVHCKEKAFTYNEC 357
C + CQ+ +T C +E +R CA G + WR+ T C E+ Y EC
Sbjct: 692 CIDEYCQTRDKTST-CDTYSELSRLCASDGPGTFESWRSDSDVVCETQRCPEQHI-YKEC 749
Query: 358 IACCPASCHPRASCVDSEIACVDGCYCPNGLIFED----GGCVAPAECPCEFHGTLYPPG 413
PA+C A DSE CV GC CP G + +D G CV AECPCE GT+Y PG
Sbjct: 750 GPSNPATCSNVAPFQDSE--CVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPG 807
Query: 414 SVVKEDCNT-CTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRS 472
V + C + CTC KW C+ A+CP C V G TTFDG +Y FP C ++ +
Sbjct: 808 EVREGPCGSQCTCQDAKWSCTEALCPGRCKVEGS-SLTTFDGVKYNFPGNCHFLAVHNED 866
Query: 473 SGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDD 532
++++++ PC Q G C+ SV+++L+ + + + D+ + Y D
Sbjct: 867 ---WSISVELRPCPSGQTGTCLNSVTLLLNSSVPVDKYVFNSDGTVTNDKIRNQGYYYSD 923
Query: 533 AFEIRRLSSVFLRVRTNVGVRV-LYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFL 591
+I SS +L+V T V++ + ++LY+ + DTVGLCG++N +DDF+
Sbjct: 924 KIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFM 983
Query: 592 SPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVL--TGEMFA 649
S + E T Q F NSW+ +S G+P C + ++ ++ + C +L + A
Sbjct: 984 SSQNILEKTSQAFANSWEMMSC----PKGNP-SSC-ISIEKEKFAERHCGILLDSSGPLA 1037
Query: 650 PCSAFLSPVPYFEQCRRDACRC--GQPCLCATLAHYAHLC-RRHGLPVDFRARLPACALS 706
C ++P PY E+C++ C C Q CLC L +Y C + V +R L C S
Sbjct: 1038 SCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGL--CEHS 1095
Query: 707 CEASKEYSPCVAPCGRTCQDLASPE-ACGVDGGDDLSRDECVEGCACPPDTYLDTQADLC 765
C + + V C +C+ L+ + +C V+ D V+GC CP Y + + + C
Sbjct: 1096 CPSGLVFKYNVKACNSSCRSLSERDRSCDVE-------DVPVDGCTCPDAMYQNNEGN-C 1147
Query: 766 VPRNQCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAA--CPAGQVFVNCSDL 823
V ++QC C+ PG C C+DG++ C C G +V+CSD
Sbjct: 1148 VLKSQCDCYINDEVMQPGKLIHTDDNKCVCRDGILLCQIPIDLTLQNCSGGAEYVDCSD- 1206
Query: 824 HTDLELSRERTC 835
+ RTC
Sbjct: 1207 -PKAQRRTNRTC 1217
Score = 126 bits (316), Expect = 3e-28
Identities = 103/403 (25%), Positives = 162/403 (40%), Gaps = 41/403 (10%)
Query: 785 SDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSV 844
SD P D + C+++ CP ++ C S TC N++
Sbjct: 718 SDGPGTFESWRSDSDVVCETQR----CPEQHIYKECGP-------SNPATCS----NVAP 762
Query: 845 SARGPCLSGCACPQGLLRHG----DACFLPEECPCTWKGKEYFPGDQVMSPCHT-CVCQR 899
C+SGC CP+G L C L ECPC G Y PG+ PC + C CQ
Sbjct: 763 FQDSECVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGEVREGPCGSQCTCQD 822
Query: 900 GSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYS 959
+ CT C C G TFDG+ ++F G C L D S SV +
Sbjct: 823 AKWSCTEALCPGRCKVEGSS-LTTFDGVKYNFPGNCHF-LAVHNEDWSISVELRPCPSGQ 880
Query: 960 SGMICRKFISINVGNSL----IVFDDDSGNPSPES-----FLDDKQEVHTWRVGFFTLVH 1010
+G C +++ + +S+ VF+ D + + + DK ++ + +
Sbjct: 881 TGT-CLNSVTLLLNSSVPVDKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASSSYLQVET 939
Query: 1011 FPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSS 1070
+ + + ++V P GLCG+++ K ++ + +N+ Q F +S
Sbjct: 940 YFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANS 999
Query: 1071 WAAVECPDTLDPRDMCVLNPLREPFAKKECSILL--SEVFEICHPVVDVTWFYSNCLTDT 1128
W + CP +P + +E FA++ C ILL S CHP+V+ ++ C T
Sbjct: 1000 WEMMSCPKG-NPSSCISIE--KEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYT 1056
Query: 1129 CGCSQGGDCECFCASVSAYAHQCCQ-HGVAVDWRTPRLCPYDC 1170
C C D C C + Y C + V WRT LC + C
Sbjct: 1057 CTCENSQD--CLCTILGNYVKACAEKETYIVGWRT-GLCEHSC 1096
Score = 112 bits (281), Expect = 4e-24
Identities = 125/511 (24%), Positives = 179/511 (35%), Gaps = 97/511 (18%)
Query: 33 CAPSYLFSCFNG-GECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRA--------W- 82
C YL G+CV A C C VY G R+ C + W
Sbjct: 774 CPEGYLLDDIGEKGKCVLKAECPCESSGT-------VYQPGEVREGPCGSQCTCQDAKWS 826
Query: 83 -------GQHHVE-----TFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSP 130
G+ VE TFDG+ Y G + V + +SI V P
Sbjct: 827 CTEALCPGRCKVEGSSLTTFDGVKYNFPGNCHFLAV-----HNEDWSISVELRPCPSGQT 881
Query: 131 YTCSRAVSLFF-----VGEQEIHLAKEVTHGGMRVQ-------LPHVMGSARLQQLAGYV 178
TC +V+L V + + VT+ +R Q + S+ Q+ Y
Sbjct: 882 GTCLNSVTLLLNSSVPVDKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASSSYLQVETYF 941
Query: 179 IVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFV 238
V+ Q +Y+ M P T GLCG+ N +DD ++S L F
Sbjct: 942 HVKLQIQIVPVMQ----LYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFA 997
Query: 239 HSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQ------CEALLRP--PFDACHA 290
+SW+ + C + NP + + ++ C LL P +CH
Sbjct: 998 NSWEMMS----------------CPKGNPSSCISIEKEKFAERHCGILLDSSGPLASCHP 1041
Query: 291 YVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKE- 349
V+P P+ C C C L Y +ACA+ + GWRT L C C
Sbjct: 1042 IVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGL--CEHSCPSG 1099
Query: 350 KAFTYNECIACCPASCH---PRASCVDSEIACVDGCYCPNGLI-FEDGGCVAPAECPCEF 405
F YN + C +SC R D E VDGC CP+ + +G CV ++C C
Sbjct: 1100 LVFKYN--VKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYI 1157
Query: 406 HGTLYPPGSVVKEDCNTCTCTSG-----------KWECSTAVCPAECSVTGDIHFTTFDG 454
+ + PG ++ D N C C G CS +CS T
Sbjct: 1158 NDEVMQPGKLIHTDDNKCVCRDGILLCQIPIDLTLQNCSGGAEYVDCSDPKAQRRTNRTC 1217
Query: 455 RRYTFPATCQYILAKSRSSGTFTVTLQNAPC 485
P Y +GTF + ++ PC
Sbjct: 1218 STRNIPVFDDYC---GHENGTFRILTESVPC 1245
Score = 105 bits (263), Expect = 5e-22
Identities = 51/142 (35%), Positives = 75/142 (52%), Gaps = 1/142 (0%)
Query: 1034 WQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSW-AAVECPDTLDPRDMCVLNPLR 1092
+QG++ GLCGN + ++ T + + EFG+SW + EC DT+ C NP
Sbjct: 1260 FQGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQTFPCDSNPYC 1319
Query: 1093 EPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCC 1152
+ +A ++C IL F CH VD + ++ C+ + C C G FC +V+ YA C
Sbjct: 1320 KAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACS 1379
Query: 1153 QHGVAVDWRTPRLCPYDCDFFN 1174
GV V WR P LCP CD++N
Sbjct: 1380 AVGVCVSWRKPNLCPVYCDYYN 1401
Score = 105 bits (262), Expect = 6e-22
Identities = 76/246 (30%), Positives = 104/246 (42%), Gaps = 29/246 (11%)
Query: 577 GLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYS 636
GLCG NG+ +DDF + S FGNSWKT CS V+ + PCD + +++
Sbjct: 1266 GLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQT--FPCDSNPYCKAWA 1323
Query: 637 VQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQP----CLCATLAHYAHLCRRHGL 692
V+ C +L F C + P Y + C +AC C C +A YA C G+
Sbjct: 1324 VRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGV 1383
Query: 693 PVDFRARLPACALSC-------EASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDE 745
V +R + C + C E Y PC +TC+D G S
Sbjct: 1384 CVSWR-KPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLV--------GQKFS--S 1432
Query: 746 CVEGC--ACPPDT-YLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGH-CHCKDGVMS 801
+EGC CP YLD CV ++CSC + V P G + G C+C G +
Sbjct: 1433 LLEGCYAKCPDSAPYLDENTMKCVSLSECSCFYNDV-IPAGGVIEDNCGRTCYCIAGQLE 1491
Query: 802 CDSRAP 807
C AP
Sbjct: 1492 CSETAP 1497
Score = 99.0 bits (245), Expect = 6e-20
Identities = 74/239 (30%), Positives = 107/239 (44%), Gaps = 26/239 (10%)
Query: 210 GLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGT 269
GLCGNNN D KDD T + +EF +SW+ +Q T + PC NP
Sbjct: 1266 GLCGNNNGDLKDDFTTRYSSVASGALEFGNSWK---TSQECSDTVAQ--TFPC-DSNPYC 1319
Query: 270 MQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSD--LCQSMGDVATWCRALAEYARACA 327
+CE L F CH V P + C + C G +C A+A YA AC+
Sbjct: 1320 KAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACS 1379
Query: 328 QAGRPLQGWRTQLRQCTVHCK------EKAFTYNECIACCPASCHPRASCVDSEI-ACVD 380
G WR + C V+C E + Y C +C + V + + ++
Sbjct: 1380 AVG-VCVSWR-KPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTC--KDQLVGQKFSSLLE 1435
Query: 381 GCY--CPNGLIFEDGG---CVAPAECPCEFHGTLYPPGSVVKEDC-NTCTCTSGKWECS 433
GCY CP+ + D CV+ +EC C F+ + P G V++++C TC C +G+ ECS
Sbjct: 1436 GCYAKCPDSAPYLDENTMKCVSLSECSC-FYNDVIPAGGVIEDNCGRTCYCIAGQLECS 1493
Score = 75.5 bits (184), Expect = 7e-13
Identities = 56/207 (27%), Positives = 89/207 (42%), Gaps = 26/207 (12%)
Query: 2174 GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDS---CATT 2230
GLCG +GD +D T + SV GA + F +SW+ + F DS C
Sbjct: 1266 GLCGNNNGDLKDDFTTRYSSVASGALE---FGNSWKTSQECSDTVAQTFPCDSNPYCKAW 1322
Query: 2231 DCSPCLRMVSNRTFSACHRFVPPESFCELWIRDT-------KYVQQPCVALTVYVAMCHK 2283
C ++ + TF CH V P ++ ++ I + KY+ C A+ +Y C
Sbjct: 1323 AVRKC-EILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGF-CTAVAMYAEACSA 1380
Query: 2284 FHVCIEWRRSDYCPFLCSSDSTYQACVTACEP-----PKTCQDGILGPLDPEHCQVLGEG 2338
VC+ WR+ + CP C + C EP KTC+D ++G + L EG
Sbjct: 1381 VGVCVSWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVG----QKFSSLLEG 1436
Query: 2339 CV--CSEGTILHRRHSALCIPEAKCAC 2363
C C + ++ C+ ++C+C
Sbjct: 1437 CYAKCPDSAPYLDENTMKCVSLSECSC 1463
Score = 73.6 bits (179), Expect = 3e-12
Identities = 124/529 (23%), Positives = 190/529 (35%), Gaps = 80/529 (15%)
Query: 1336 CEWRYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCP-TPQVLDEVTQRCVYLEDC--- 1391
C W Y+ C + +TC+D + + +EGC CP + LDE T +CV L +C
Sbjct: 1406 CRWHYEPCGTVTAKTCKD-QLVGQKFSSLLEGCYAKCPDSAPYLDENTMKCVSLSECSCF 1464
Query: 1392 ---VEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTAL 1448
V PA V + G T G S+ P S + T T L+ A +T
Sbjct: 1465 YNDVIPAGGVIEDNCG-RTCYCIAGQLECSETAPTNSTFAVSTTTATTILSTGAAITLVT 1523
Query: 1449 NPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSS 1508
P TA P ++ ++TT GP P + G+T + + I T ++
Sbjct: 1524 GGPSTAASIPAITTSSSETT----------GTTLGPLTEPFTTGITETSVPIISTSGNAG 1573
Query: 1509 LPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLP 1568
+ + G A T V G+ + S R+ PR T AV G GS
Sbjct: 1574 MTGVVSPTVTGASGMAGTTGGVDAATTGAASENTSERA-GTPRVSGATPAV---GGGS-- 1627
Query: 1569 VRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQS 1628
TP + A+ S S G+I+ SP +S A + S++G P+
Sbjct: 1628 ---TPGEAGPGATVSGSTGVSAGSITASPGAS---------ATSSESSKSGTTGPSVGGK 1675
Query: 1629 ASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAP 1688
+ S+ T + + S +T + ++ + G SP P P +P
Sbjct: 1676 TGATSSEATSSEGMSGVTGQSLGSTAGSDSEITAKTSFTG-----SSPPGKLTRPSPGSP 1730
Query: 1689 PRPAQHTT------------------MATRSPALPPETPAAASLSTATDG---------- 1720
+ TT + + ++ T A + + T G
Sbjct: 1731 GHFSGGTTEWGNVATTGAAGENTSGALGSTEGSVEATTSAGSGNTAGTSGTGDTGPGNTA 1790
Query: 1721 LAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAPVA----TPGPKASVITTPLQPQA 1776
++ TP +S +T P S P + + G S T A + TP A
Sbjct: 1791 VSGTPVVSPGAT-PGAPGSSTPGEADIGNTSFGKSGKSGHDSLTVLNPAFLRRTPTVSAA 1849
Query: 1777 TTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSG 1825
+T T SPV T AA A + P GT G G + TSG
Sbjct: 1850 ST----TSSPVSKHTDAASATAVTISGSKPGTPGTPGGATSGGKI-TSG 1893
Score = 49.7 bits (117), Expect = 4e-05
Identities = 91/424 (21%), Positives = 152/424 (35%), Gaps = 59/424 (13%)
Query: 1975 TSTTCVPIAEQDCVRHI-CLEGQLIR-VNQSQHCPQGAAPPRCGILGLAVRVG------- 2025
T + P + +CV C EG L+ + + C A P C G + G
Sbjct: 756 TCSNVAPFQDSECVSGCTCPEGYLLDDIGEKGKCVLKAECP-CESSGTVYQPGEVREGPC 814
Query: 2026 GDRC--------CPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHV 2077
G +C C C RC + S TFDG ++ + D ++V +
Sbjct: 815 GSQCTCQDAKWSCTEALCPGRCKV-EGSSLTTFDGVKYNFPGNCHFLAVHNEDWSISVEL 873
Query: 2078 LDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDR--FNRKVTVDLQPVWPPVSRYGFRIE 2135
C S G CL + + L V +D+ FN TV + Y +I+
Sbjct: 874 RPCPSGQTGT------CLNSVTLL-LNSSVPVDKYVFNSDGTVTNDKIRNQGYYYSDKIQ 926
Query: 2136 --DTGHMYMILTPS---DIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLK 2190
+ Y+ + +QIQ + L V GLCG + A +D
Sbjct: 927 IFNASSSYLQVETYFHVKLQIQIVPVMQLY-VSMPPNQFTDTVGLCGSYNNKAEDDFMSS 985
Query: 2191 DGSVVGGAEDPAPFLDSWQV-------PSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRT 2243
+ ++ F +SW++ PSS S+ + +F C + + S+
Sbjct: 986 QNILEKTSQ---AFANSWEMMSCPKGNPSSCISIEKEKFAERHCG-------ILLDSSGP 1035
Query: 2244 FSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCIEWRRSDYCPFL 2299
++CH V P+ + E + T + C L YV C + I R+ C
Sbjct: 1036 LASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHS 1095
Query: 2300 CSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEA 2359
C S ++ V AC D E V +GC C + +++ + C+ ++
Sbjct: 1096 CPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPV--DGCTCPDA--MYQNNEGNCVLKS 1151
Query: 2360 KCAC 2363
+C C
Sbjct: 1152 QCDC 1155
Score = 42.7 bits (99), Expect = 0.005
Identities = 41/187 (21%), Positives = 71/187 (37%), Gaps = 49/187 (26%)
Query: 810 ACPAGQVFVN----CSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGD 865
+CP+G VF C+ L R+R+C+ + + + GC CP + ++ +
Sbjct: 1095 SCPSGLVFKYNVKACNSSCRSLS-ERDRSCDVEDVPVD---------GCTCPDAMYQNNE 1144
Query: 866 A-CFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQC------TLHPCAS------- 911
C L +C C + PG + + + CVC+ G C TL C+
Sbjct: 1145 GNCVLKSQCDCYINDEVMQPGKLIHTDDNKCVCRDGILLCQIPIDLTLQNCSGGAEYVDC 1204
Query: 912 --------TCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSSGMI 963
T R+ FD D+ G + +F ++ E+V C G+
Sbjct: 1205 SDPKAQRRTNRTCSTRNIPVFD----DYCG---------HENGTFRILTESVPCCEDGLT 1251
Query: 964 CRKFISI 970
C + I +
Sbjct: 1252 CSRKIIV 1258
>gi|134268640 tectorin alpha precursor [Homo sapiens]
Length = 2155
Score = 237 bits (605), Expect = 1e-61
Identities = 210/797 (26%), Positives = 321/797 (40%), Gaps = 105/797 (13%)
Query: 73 PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHND-PQCGSSPY 131
P+R+++C + TFDG Y + SYTL+ + I ++ P G +
Sbjct: 707 PKRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERPEYLEIDINKKKPDAGPAWL 766
Query: 132 TCSRAVSLFFVGEQEIHL----AKEVTHGGMRVQLP--HVMGSARLQQLAGYVIVRHQSA 185
R + V +QE+ + A EV G V+LP H G + + V +
Sbjct: 767 RGLRIL----VADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVESKGV 822
Query: 186 FTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ--E 243
T+ + +YI++S T GLCG NA+ D+ +GK TD++ F+ SW E
Sbjct: 823 VTVQYSDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTFE 882
Query: 244 QAPNQPPGPTTSSLPRPPCLQQNPGTMQGVY---EQCEALLRP---PFDACHAYVSPLPF 297
+ N G + N + Y +C + P F CH V+ +
Sbjct: 883 EICNGECGDLLKAC-------NNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAY 935
Query: 298 TASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNEC 357
+C LCQS G+ + C ++A YA AC A + WRT C + C E + + EC
Sbjct: 936 YRTCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRT-YDFCPLECPENSH-FEEC 993
Query: 358 IACCPASCHPRA---SCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGS 414
I C +C CVDS C +GC C G CV +EC C F G
Sbjct: 994 IT-CTETCETLTLGPICVDS---CSEGCQCDEGYALLGSQCVTRSECGCNFEGHQLATNE 1049
Query: 415 V--VKEDCNT---CTCTSGKWECSTAVC-------------------PAECSVTGDIHFT 450
V DC C+ T + C T C A C V+G H+
Sbjct: 1050 TFWVDLDCQIFCYCSGTDNRVHCETIPCKDDEYCMEEGGLYYCQARTDASCIVSGYGHYL 1109
Query: 451 TFDGRRYTFPATCQYILA------KSRSSGTFTVTLQN------APCGLNQDGACVQSVS 498
TFDG + F +C IL S S F VT +N + Q V S
Sbjct: 1110 TFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNEDRDPSLALWVKQVDVTVFGYS 1169
Query: 499 VILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVF-LRVRTNVGVRVLYD 557
+++H+ + V L + ++ P +I S F + V T+ G++V+YD
Sbjct: 1170 IVIHRAYKHTV---------LVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYD 1220
Query: 558 REGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPL 617
+ L + V + T GLCG +NGN DD P+G+ S+ FG SW +
Sbjct: 1221 WKTF-LSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKRDTFCQV 1279
Query: 618 VSGSPLDPCDVHLQAASYSVQACSVLTGE--MFAPCSAFLSPVPYFEQCRRDACRCG--Q 673
G C ++ S Q CS++ + F+ C + ++P +++ C D+C G
Sbjct: 1280 GCGDRCPSC-AKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGAV 1338
Query: 674 PCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEAC 733
C+ L +YA C+ G+ V +C ++C + Y CV+ C C + C
Sbjct: 1339 QTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCAAIRLKSDC 1398
Query: 734 GVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPP----GDSDIPS 789
CVEGC C L+ ++ C+ + C C+ G Y P +SD
Sbjct: 1399 S---------HYCVEGCHCDAGYVLNGKS--CILPHSCGCYSDGKYYEPKQLFWNSDCTR 1447
Query: 790 LGHCHC-KDGVMSCDSR 805
C C + V+ CD R
Sbjct: 1448 --RCRCFRRNVIQCDPR 1462
Score = 202 bits (513), Expect = 5e-51
Identities = 200/816 (24%), Positives = 318/816 (38%), Gaps = 78/816 (9%)
Query: 41 CFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGK 100
C + ++ C + P+ + Y + E S C +G+ H TFDG ++ G
Sbjct: 285 CLDFNNEIYCQEASCSPYEVCEPKGKFFYCSAVET-STCVVFGEPHYHTFDGFLFHFQGS 343
Query: 101 GSYTLVGRHEPEGQS---FSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGG 157
+Y L+ R + S FS++ N+ + GS+ + + +S+ G + L + ++G
Sbjct: 344 CAY-LLARQCLQTSSLPFFSVEAKNEHRRGSA-VSWVKELSVEVNGYKI--LIPKGSYGR 399
Query: 158 MRVQ-----LPHVM--GSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHG 210
++V LP + G+ ++ Q V + +DG I + + T G
Sbjct: 400 VKVNDLVTSLPVTLDLGTVKIYQSGISTAVETDFGLLVTFDGQHYASISVPGSYINSTCG 459
Query: 211 LCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTM 270
LCGN N +P DD + G+ V++ SW+ + S C Q + T
Sbjct: 460 LCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHADWK----CDSGCVDNCTQCDAAT- 514
Query: 271 QGVY---EQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARA 325
+ +Y + C L + P C V P F SC DLC + C+A+ YA
Sbjct: 515 EALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALV 574
Query: 326 CAQAGRPLQGWRTQLR-QCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYC 384
C G P+ WRTQ TV C + Y+ C + CP +C + + C +GC C
Sbjct: 575 CQALGIPIGDWRTQTGCVSTVQCPSFSH-YSVCTSSCPDTCSDLTASRNCATPCTEGCEC 633
Query: 385 PNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCN---TCTCTSG-------KWECST 434
G + CV +C C+F G Y G N C C G K S
Sbjct: 634 NQGFVLSTSQCVPLHKCGCDFDGHYYTMGEFFWATANCTVQCLCEEGGDVYCFNKTCGSG 693
Query: 435 AVCPAE-------------CSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQ 481
VC E C ++ + TFDG Y FP+ Y L K+ + +
Sbjct: 694 EVCAVEDGYQGCFPKRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERPEYLEID 753
Query: 482 NAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPY-TDDAFEIRRLS 540
+ A ++ + +++ D ++ A +V L Q +P + EI R +
Sbjct: 754 INKKKPDAGPAWLRGLRILV-ADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYR-N 811
Query: 541 SVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPEST 600
V + V V Y GL LY+++ + T GLCG +N N D+F P G
Sbjct: 812 KNSTTVESKGVVTVQYSDIGL-LYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDN 870
Query: 601 PQLFGNSWKTLSACSPLVSGSPLDPC--DVHLQAASYSVQACSVL---TGEMFAPCSAFL 655
+F SW T G L C D L S C ++ + F C +
Sbjct: 871 LAVFLESWTTFEEICNGECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVV 930
Query: 656 SPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEY 713
+ Y+ C C+ G + LC ++A YA C+ + V C L C + +
Sbjct: 931 NVTAYYRTCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHF 990
Query: 714 SPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSC 773
C+ C TC+ L C D C EGC C D CV R++C C
Sbjct: 991 EECIT-CTETCETLTLGPIC---------VDSCSEGCQC--DEGYALLGSQCVTRSECGC 1038
Query: 774 HFQGVDYPPGDS---DIPSLGHCHCK--DGVMSCDS 804
+F+G ++ D+ C+C D + C++
Sbjct: 1039 NFEGHQLATNETFWVDLDCQIFCYCSGTDNRVHCET 1074
Score = 182 bits (461), Expect = 5e-45
Identities = 185/718 (25%), Positives = 268/718 (37%), Gaps = 72/718 (10%)
Query: 68 VYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGR-HEPEGQSFS---IQVHND 123
+Y D+ C G H TFDG + L P SF + N+
Sbjct: 1089 LYYCQARTDASCIVSGYGHYLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNE 1148
Query: 124 PQCGSSPYTCSRAVSLFFVGEQEIHLAKE--VTHGGMRVQLPHVMGSARLQ--QLAGYVI 179
+ S + F IH A + V R+ LP +G ++ +V+
Sbjct: 1149 DRDPSLALWVKQVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVV 1208
Query: 180 VRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVH 239
V + +D + + I + + T+GLCG N +P DDL G L V EF
Sbjct: 1209 VETDFGLKVVYDWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQ 1268
Query: 240 SWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEAL--LRPPFDACHAYVSPLPF 297
SW ++ G P C + V + C + F CH+ V+P F
Sbjct: 1269 SWVKRDTFCQVGCGDRC---PSCAKVEG--FSKVQQLCSLIPNQNAAFSKCHSKVNPTFF 1323
Query: 298 TASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNEC 357
+C D C G V T C L YA C G + GWR CTV C + Y C
Sbjct: 1324 YKNCLFDSCIDGGAVQTACSWLQNYASTCQTQGITVTGWRNYT-SCTVTCPPNSH-YESC 1381
Query: 358 IACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVV- 416
++ C C D CV+GC+C G + C+ P C C G Y P +
Sbjct: 1382 VSVCQPRCAAIRLKSDCSHYCVEGCHCDAGYVLNGKSCILPHSCGCYSDGKYYEPKQLFW 1441
Query: 417 KEDCNT-CTC-TSGKWECSTAVCPAE-------------------CSVTGDIHFTTFDGR 455
DC C C +C C ++ C G F TFDG
Sbjct: 1442 NSDCTRRCRCFRRNVIQCDPRQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGA 1501
Query: 456 RYTFPATCQYILAKSRSSGTFTVTLQNAPCGL--NQDGACVQSVSVI---LHQDPRRQVT 510
FPA C ++L+ T L + L N D ++++I Q+
Sbjct: 1502 FLRFPANCAFVLS------TICQKLPDISFQLIINFDKWSAPNLTIISPVYFYINEEQIL 1555
Query: 511 LTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQR 570
+ V + +P T A +I S FL + T+ +++ Y+ + + + + +R
Sbjct: 1556 INDRNTVKVNGTQVNVPFITGLATKIYS-SEGFLVIDTSPDIQIYYNGFNV-IKISISER 1613
Query: 571 WVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKT--------LSACSPLVSGSP 622
GLCG FNG+ DD+++ G P + + SWKT +C+ L
Sbjct: 1614 LQNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKTNGMQKRPLAPSCNELQFSQY 1673
Query: 623 LDPCD-VHLQAASYSVQACSVLTG--EMFAPCSAFLSPVPYFEQCRRDACRCGQPC-LCA 678
CD VH+Q C LT F PC L P+P++E C D C + LC
Sbjct: 1674 AAMCDNVHIQKMQ-GDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYLDGCYSHKKFQLCG 1732
Query: 679 TLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCV-APC-GRTCQDLASPEACG 734
+LA Y CR G+ C+ E PCV A C RTC+ E CG
Sbjct: 1733 SLAAYGEACRSFGILSTEWIEKENCSGVVE-----DPCVGADCPNRTCELGNGRELCG 1785
Score = 134 bits (337), Expect = 1e-30
Identities = 119/454 (26%), Positives = 184/454 (40%), Gaps = 56/454 (12%)
Query: 375 EIACVDGC-----YCPNGLIF-EDGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCT-- 426
EI +GC + G +F +D C C +F+ +Y C +C+
Sbjct: 253 EIDPANGCTSRGQFLRRGEVFWDDLNCTVKCRC-LDFNNEIY---------CQEASCSPY 302
Query: 427 -----SGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAK----SRSSGTFT 477
GK+ +AV + C V G+ H+ TFDG + F +C Y+LA+ + S F+
Sbjct: 303 EVCEPKGKFFYCSAVETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFS 362
Query: 478 VTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQA--GDVLLFDQYKIIPPYTDDAFE 535
V +N ++ G+ V V + + ++ + + G V + D +P D
Sbjct: 363 VEAKNE----HRRGSAVSWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTV 418
Query: 536 IRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVG 595
S + V T+ G+ V +D + + V ++ T GLCG +N N DDFL P G
Sbjct: 419 KIYQSGISTAVETDFGLLVTFDGQHYAS-ISVPGSYINSTCGLCGNYNKNPLDDFLRPDG 477
Query: 596 VPESTPQLFGNSWKTLSACSPLVSG--SPLDPCDVHLQAASYSVQACSVL--TGEMFAPC 651
P + G SW+ A SG CD +A + C L T C
Sbjct: 478 RPAMSVLDLGESWRVYHADWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGPLWEC 537
Query: 652 SAFLSPVPYFEQCRRDAC--RCGQPCLCATLAHYAHLCRRHGLPV-DFRARLPACA-LSC 707
+ P + C D C R LC + YA +C+ G+P+ D+R + + + C
Sbjct: 538 GTVVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQC 597
Query: 708 EASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVP 767
+ YS C + C TC DL + C C EGC C L T CVP
Sbjct: 598 PSFSHYSVCTSSCPDTCSDLTASRNCAT---------PCTEGCECNQGFVLSTSQ--CVP 646
Query: 768 RNQCSCHFQGVDYPPGD---SDIPSLGHCHCKDG 798
++C C F G Y G+ + C C++G
Sbjct: 647 LHKCGCDFDGHYYTMGEFFWATANCTVQCLCEEG 680
Score = 112 bits (279), Expect = 7e-24
Identities = 104/403 (25%), Positives = 158/403 (39%), Gaps = 57/403 (14%)
Query: 811 CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLP 870
CP F C ++ TCE L L C GC C +G G C
Sbjct: 984 CPENSHFEEC--------ITCTETCET--LTLGPICVDSCSEGCQCDEGYALLGSQCVTR 1033
Query: 871 EECPCTWKGKE-----------------YFPGDQVMSPCHTCVC--------QRGSFQCT 905
EC C ++G + Y G C T C + G + C
Sbjct: 1034 SECGCNFEGHQLATNETFWVDLDCQIFCYCSGTDNRVHCETIPCKDDEYCMEEGGLYYCQ 1093
Query: 906 LHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLV------KSTSDVSFSVIVENVNCYS 959
AS C G HY TFDG PFDF +C + L S S F V +N +
Sbjct: 1094 ARTDAS-CIVSGYGHYLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNEDRDP 1152
Query: 960 SGMICRKFISINV-GNSLIV---FDDDSGNPSPESFLDDK---QEVHTWRVGFFTLVHFP 1012
S + K + + V G S+++ + S +L K +++ + GF +V
Sbjct: 1153 SLALWVKQVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVE-T 1211
Query: 1013 QEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWA 1072
+ +++D +T + + Q GLCG ++ +++ P L ++ EFG SW
Sbjct: 1212 DFGLKVVYDWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWV 1271
Query: 1073 AVECPDTLDPRDMCVLNPLREPFAKKE--CSILLSE--VFEICHPVVDVTWFYSNCLTDT 1128
+ + D C E F+K + CS++ ++ F CH V+ T+FY NCL D+
Sbjct: 1272 KRDTFCQVGCGDRCPSCAKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDS 1331
Query: 1129 CGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1170
C GG + C+ + YA C G+ V WR C C
Sbjct: 1332 --CIDGGAVQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTC 1372
Score = 84.3 bits (207), Expect = 2e-15
Identities = 82/338 (24%), Positives = 128/338 (37%), Gaps = 27/338 (7%)
Query: 852 SGCACPQGLLRHGDACF----LPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLH 907
+GC LR G+ + +C C E + + SP C + F C+
Sbjct: 258 NGCTSRGQFLRRGEVFWDDLNCTVKCRCLDFNNEIYCQEASCSPYEVCEPKGKFFYCSAV 317
Query: 908 PCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVS----FSVIVENVNCYSSGMI 963
STC +G+ HY TFDG F F G+C L + S FSV +N + S +
Sbjct: 318 E-TSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHRRGSAVS 376
Query: 964 CRKFISINV-GNSLIVFDDDSGNPSPESFLD------DKQEVHTWRVGFFTLVHFPQEHI 1016
K +S+ V G +++ G + D V ++ G T V +
Sbjct: 377 WVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQSGISTAVE-TDFGL 435
Query: 1017 TLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSW----A 1072
+ +D + + + GLCGN++ +++ P+ + + G SW A
Sbjct: 436 LVTFDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHA 495
Query: 1073 AVECPD-TLDPRDMCVLNPLREPFAKKECSILLSEVFEI--CHPVVDVTWFYSNCLTDTC 1129
+C +D C F C L + C VVD T F +C+ D C
Sbjct: 496 DWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLC 555
Query: 1130 GCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLC 1166
G C ++ AYA C G+ + DWRT C
Sbjct: 556 SVRDNG--TLLCQAIQAYALVCQALGIPIGDWRTQTGC 591
Score = 72.4 bits (176), Expect = 6e-12
Identities = 92/403 (22%), Positives = 142/403 (35%), Gaps = 58/403 (14%)
Query: 811 CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLP 870
CP+ + C+ D TC L S + PC GC C QG + C
Sbjct: 597 CPSFSHYSVCTSSCPD-------TCSD--LTASRNCATPCTEGCECNQGFVLSTSQCVPL 647
Query: 871 EECPCTWKGKEYFPGDQVMSPCHT---CVCQRGS-FQCTLHPCAS--------------- 911
+C C + G Y G+ + + C+C+ G C C S
Sbjct: 648 HKCGCDFDGHYYTMGEFFWATANCTVQCLCEEGGDVYCFNKTCGSGEVCAVEDGYQGCFP 707
Query: 912 ----TCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD-VSFSVIVENVNCYSSGMICRK 966
C ++ TFDG + F L+K+ + + I N +G +
Sbjct: 708 KRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERPEYLEIDINKKKPDAGPAWLR 767
Query: 967 FISINVGNSLIVFDDD-------SGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLL 1019
+ I V + + +G F ++ +R T V + +T+
Sbjct: 768 GLRILVADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVE-SKGVVTVQ 826
Query: 1020 WDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVE---- 1075
+ ++++ + GLCG ++ +E P N F SW E
Sbjct: 827 YSDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTFEEICN 886
Query: 1076 --CPDTLDP--RDMCVLNPLREPFAKKECSIL---LSEVFEICHPVVDVTWFYSNCLTDT 1128
C D L D +L R ++ C I+ + F CH VV+VT +Y CL
Sbjct: 887 GECGDLLKACNNDSELLKFYR---SRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRL 943
Query: 1129 CGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1170
C GG+ C SV+ YA C V V WRT CP +C
Sbjct: 944 --CQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLEC 984
Score = 70.5 bits (171), Expect = 2e-11
Identities = 70/286 (24%), Positives = 114/286 (39%), Gaps = 30/286 (10%)
Query: 2158 GLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSV 2217
GL+ + S T GLCG + +A+++ L +G ++ A FL+SW + +
Sbjct: 831 GLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCT---DNLAVFLESWTTFEEICN- 886
Query: 2218 GQTRFRPDSCATTD--------CSPC--LRMVSNRTFSACHRFVPPESFCELWI----RD 2263
G+ +C S C + SN +F CH V ++ + +
Sbjct: 887 GECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRLCQS 946
Query: 2264 TKYVQQPCVALTVYVAMCHKFHVCI-EWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDG 2322
+ C ++ Y + C V + WR D+CP C +S ++ C+T E TC+
Sbjct: 947 GGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEECITCTE---TCETL 1003
Query: 2323 ILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLS 2382
LGP+ + C EGC C EG L + C+ ++C C + G A ET+ L
Sbjct: 1004 TLGPICVDSC---SEGCQCDEGYAL---LGSQCVTRSECGC-NFEGHQLATNETFWVDLD 1056
Query: 2383 GCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCL 2428
C D V + P E C+ G + D C+
Sbjct: 1057 CQIFCYCSGTDNRVHCET-IPCKDDEYCMEEGGLYYCQARTDASCI 1101
Score = 70.1 bits (170), Expect = 3e-11
Identities = 79/361 (21%), Positives = 128/361 (35%), Gaps = 49/361 (13%)
Query: 850 CLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVM-SPC-HTCVC-QRGSFQCTL 906
C+ GC C G + +G +C LP C C GK Y P S C C C +R QC
Sbjct: 1402 CVEGCHCDAGYVLNGKSCILPHSCGCYSDGKYYEPKQLFWNSDCTRRCRCFRRNVIQCDP 1461
Query: 907 HPC-------------------ASTCTAYGDRHYRTFDGLPFDFVGACKVHL---VKSTS 944
C S C A G +RTFDG F C L +
Sbjct: 1462 RQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANCAFVLSTICQKLP 1521
Query: 945 DVSFSVIVENVNCYSSGMICRKFISINVGNSLIVFDDD-----SGNPSPESFLDDKQEVH 999
D+SF +I+ + + + + I+ +D +G F+
Sbjct: 1522 DISFQLIINFDKWSAPNLTIISPVYFYINEEQILINDRNTVKVNGTQVNVPFITGLATKI 1581
Query: 1000 TWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENL 1059
GF + P I + ++ + + + Q ++ GLCGNF+ ++ T
Sbjct: 1582 YSSEGFLVIDTSPD--IQIYYNGFNVIKISISERLQNKVCGLCGNFNGDLTDDYVTLRGK 1639
Query: 1060 ELTNPQEFGSSW---------AAVECPDTLDPR--DMCVLNPLREPFAKKECSIL--LSE 1106
+ + SW A C + + MC +++ C L +
Sbjct: 1640 PVVSSVVLAQSWKTNGMQKRPLAPSCNELQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKG 1699
Query: 1107 VFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGV-AVDWRTPRL 1165
F+ C+ ++D FY +C D C + C S++AY C G+ + +W
Sbjct: 1700 FFQPCYGLLDPLPFYESCYLDGCYSHKKFQ---LCGSLAAYGEACRSFGILSTEWIEKEN 1756
Query: 1166 C 1166
C
Sbjct: 1757 C 1757
Score = 68.2 bits (165), Expect = 1e-10
Identities = 81/368 (22%), Positives = 138/368 (37%), Gaps = 44/368 (11%)
Query: 2098 LNMTHLAHQVTIDR-FNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHS 2156
+++T + + I R + V V+ + ++ P+ +I + ++ +D ++ ++
Sbjct: 1161 VDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYD 1220
Query: 2157 -SGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLT 2215
+ + ++ + +GLCG +G+ +DL + G + + F SW +
Sbjct: 1221 WKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNE---FGQSWVKRDTFC 1277
Query: 2216 SVGQTRFRPDSCATTDCSPCLRMVS-----NRTFSACHRFVPPESFCELWIRDTKY---- 2266
VG P S ++ S N FS CH V P F + + D+
Sbjct: 1278 QVGCGDRCPSCAKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGA 1337
Query: 2267 VQQPCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILG 2325
VQ C L Y + C + + WR C C +S Y++CV+ C+P C I
Sbjct: 1338 VQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQP--RCA-AIRL 1394
Query: 2326 PLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCC 2385
D H V EGC C G +L+ + CI C C WNS + C
Sbjct: 1395 KSDCSHYCV--EGCHCDAGYVLNGKS---CILPHSCGCYSDGKYYEPKQLFWNSDCTRRC 1449
Query: 2386 Q-----------HQCQAPDTIVPVD--LGCPSPRPESCL--------RFGEVALLLPTKD 2424
+ QC++ + + GC S + CL F L P
Sbjct: 1450 RCFRRNVIQCDPRQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANC 1509
Query: 2425 PCCLGTVC 2432
L T+C
Sbjct: 1510 AFVLSTIC 1517
Score = 53.9 bits (128), Expect = 2e-06
Identities = 65/277 (23%), Positives = 101/277 (36%), Gaps = 43/277 (15%)
Query: 2174 GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCS 2233
GLCG + + +D DG D +SW+V + ++ DS +C+
Sbjct: 459 GLCGNYNKNPLDDFLRPDGRPAMSVLDLG---ESWRVYHA-------DWKCDSGCVDNCT 508
Query: 2234 PCLRMVSNRTFSA---------------CHRFVPPESFCELWIRDTKYVQQP----CVAL 2274
C F + C V P +F + D V+ C A+
Sbjct: 509 QCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQAI 568
Query: 2275 TVYVAMCHKFHVCI-EWRRSDYC--PFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEH 2331
Y +C + I +WR C C S S Y C ++C P TC D
Sbjct: 569 QAYALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSSC--PDTCSDLTASRNCATP 626
Query: 2332 CQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQA 2391
C EGC C++G +L ++ C+P KC C D G +GE + ++ + Q C+
Sbjct: 627 CT---EGCECNQGFVL---STSQCVPLHKCGC-DFDGHYYTMGEFFWATANCTVQCLCEE 679
Query: 2392 PDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCL 2428
+ + C S E C P ++ CL
Sbjct: 680 GGDVYCFNKTCGS--GEVCAVEDGYQGCFPKRETVCL 714
Score = 40.4 bits (93), Expect = 0.025
Identities = 69/305 (22%), Positives = 111/305 (36%), Gaps = 50/305 (16%)
Query: 2047 FVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHL--- 2103
F TFDG+ + ++LS ++ + + W L +++ +
Sbjct: 1495 FRTFDGAFLRFPANCAFVLSTICQKLPDISF----QLIINFDKWSAPNLTIISPVYFYIN 1550
Query: 2104 AHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVE 2163
Q+ I+ N Q P ++ +I + +I T DIQI + +G +++
Sbjct: 1551 EEQILINDRNTVKVNGTQVNVPFITGLATKIYSSEGFLVIDTSPDIQIYY---NGFNVIK 1607
Query: 2164 ASKTSKAQGH--GLCGICDGDAAND-LTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQT 2220
S + + Q GLCG +GD +D +TL+ VV SW+ T+ Q
Sbjct: 1608 ISISERLQNKVCGLCGNFNGDLTDDYVTLRGKPVVSS----VVLAQSWK-----TNGMQK 1658
Query: 2221 RFRPDSCATTDCSP------------------CLRMVSNR-TFSACHRFVPPESFCELWI 2261
R SC S CL++ + F C+ + P F E
Sbjct: 1659 RPLAPSCNELQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYESCY 1718
Query: 2262 RDTKYVQ---QPCVALTVYVAMCHKFHV-CIEWRRSDYCPFLCSSDSTYQACVTACEPPK 2317
D Y Q C +L Y C F + EW + C S CV A P +
Sbjct: 1719 LDGCYSHKKFQLCGSLAAYGEACRSFGILSTEWIEKENC-----SGVVEDPCVGADCPNR 1773
Query: 2318 TCQDG 2322
TC+ G
Sbjct: 1774 TCELG 1778
>gi|16554449 zonadhesin isoform 3 [Homo sapiens]
Length = 2812
Score = 230 bits (586), Expect = 2e-59
Identities = 201/752 (26%), Positives = 299/752 (39%), Gaps = 77/752 (10%)
Query: 79 CRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS----FSIQVHNDPQCGSSPYTCS 134
C +G H TFDG ++ GK +Y L +P G S F + N+ Q G +C
Sbjct: 1156 CLVYGDPHYVTFDGRHFGFMGKCTYILA---QPCGNSTDPFFRVTAKNEEQ-GQEGVSCL 1211
Query: 135 RAVSLFFVGEQEIHLAK--EVTHGGMRVQLPHVMGSARLQQLAG-YVIVRHQSAFTLAWD 191
V + + E + L K GG +V LP + +G +V ++ + + WD
Sbjct: 1212 SKVYVT-LPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWD 1270
Query: 192 GASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPG 251
G +Y+ +S G GLCGN + + +D + G D E +SWQ
Sbjct: 1271 GDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQEC 1330
Query: 252 PTTSSLPRPPCLQQNPGTMQGVYEQCEALL--RPPFDACHAYVSPLPFTASCTSDLCQSM 309
+ P C +M G C L+ PF+ C +V F SC D+C
Sbjct: 1331 QKYQVVNSPSCDSSLQSSMSGP-GFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQ 1389
Query: 310 GDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRA 369
G C ++ C AG ++ WR + C + C + Y+ C CP +CH
Sbjct: 1390 GLQHLLCTHMSTMTTTCQDAGHAVKPWR-EPHFCPMACPPNS-KYSLCAKPCPDTCHSGF 1447
Query: 370 SCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSV-------VKEDC-N 421
S + CV+ C C G + C+ ++C C L+P GS K C
Sbjct: 1448 SGMFCSDRCVEACECNPGFVLSGLECIPRSQCGC-----LHPAGSYFKVGERWYKPGCKE 1502
Query: 422 TCTCTSGK------WECST--------------AVCPAECSVTGDIHFTTFDGRRYTFPA 461
C C S W C A A C+ +GD H+ TFDG + F
Sbjct: 1503 LCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMG 1562
Query: 462 TCQYILAK---SRSSGT-FTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDV 517
TC Y+L + SRS + F V+ N G + + +++V V + ++L + V
Sbjct: 1563 TCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFD---LSISLLRGCKV 1619
Query: 518 LLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVG 577
+L +P + RLSS + + TN G++V YD L + + V + G
Sbjct: 1620 MLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHL-VEVTVPSSYGGQLCG 1678
Query: 578 LCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSP---LVSGSPLDPCDVHLQAAS 634
LCG +N N+ DD L P G +WK + P LV G P C + A +
Sbjct: 1679 LCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKP-SSCQENSMADA 1737
Query: 635 YSVQACSVLTGEM--FAPCSAFLSPVPYFEQCRRDAC--RCGQPCLCATLAHYAHLCRRH 690
++ + C++L F+ C + P F C C + LC +L YA LC +
Sbjct: 1738 WN-KNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQA 1796
Query: 691 GLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGC 750
G +R R C + C YSPC +PC TC + +P C C E C
Sbjct: 1797 GQAPAWRNR-TFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCP-------KALPCAESC 1848
Query: 751 ACPPDTYLDTQADLCVPRNQCSCHFQGVDYPP 782
C L + CVP QC C Y P
Sbjct: 1849 ECQKGHILSGTS--CVPLGQCGCTDPAGSYHP 1878
Score = 224 bits (570), Expect = 1e-57
Identities = 218/885 (24%), Positives = 348/885 (39%), Gaps = 127/885 (14%)
Query: 25 ERRLHRAKCAPSYLFS---CFNGGEC--VHPA-----------------FCDCRRFNATG 62
+R + +C P ++ S C +C +HPA C C N
Sbjct: 1454 DRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRI- 1512
Query: 63 PRCQM--------------VYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGR 108
RCQ +Y + + C A G H TFDG ++ G +Y L
Sbjct: 1513 -RCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRP 1571
Query: 109 HEPEGQS--FSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAK--EVTHGGMRVQLPH 164
Q F + N+ + G + +AV + V + I L + +V G RV LP
Sbjct: 1572 CWSRSQDSYFVVSATNENRGGILEVSYIKAVHVT-VFDLSISLLRGCKVMLNGHRVALPV 1630
Query: 165 VMGSAR--LQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDD 222
+ R ++ + V++ + +DG+ V + + G GLCGN N + DD
Sbjct: 1631 WLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDD 1690
Query: 223 LVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQ-CEALL 281
+ KL D ++ +W+ ++P +P Q+N +M + + C L+
Sbjct: 1691 NLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGG--KPSSCQEN--SMADAWNKNCAILI 1746
Query: 282 RP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQ 339
P PF CH V P ASC C + GD CR+L YA CAQAG+ WR +
Sbjct: 1747 NPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQ-APAWRNR 1805
Query: 340 LRQCTVHCKEKAFTYNECIACCPASC----HPRASCVDSEIACVDGCYCPNGLIFEDGGC 395
C + C + +Y+ C + CP +C +PR C + C + C C G I C
Sbjct: 1806 -TFCPMRCPPGS-SYSPCSSPCPDTCSSINNPR-DC-PKALPCAESCECQKGHILSGTSC 1861
Query: 396 VAPAECPC-EFHGTLYPPGS--VVKEDC-NTCTCT-SGKWECSTAVCPAE---------- 440
V +C C + G+ +P G + C CTC+ C + C
Sbjct: 1862 VPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLL 1921
Query: 441 ---------CSVTGDIHFTTFDGRRYTFPATCQYILAK----SRSSGTFTVTLQNAPCGL 487
C + G+ H+ +FDG ++ P C +L K + + F ++ ++
Sbjct: 1922 RCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEG 1981
Query: 488 NQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVR 547
+ + V + ++ QVTL + VL+ + +P + + SS++ V
Sbjct: 1982 GTEAFRLHEVYIDIYD---AQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVN 2038
Query: 548 TNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNS 607
+GV+V +D L L +++ + G+CG FN +D+ + P ++ F NS
Sbjct: 2039 IKIGVQVKFDGNHL-LEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNS 2097
Query: 608 WKTLS---ACSPLVSGSPLDPCD-----------VHLQAASYSVQACSVLTGEMFAPCSA 653
WK +C L+ P + L+ A +A L ++A C++
Sbjct: 2098 WKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEA--ALRAPVWAQCAS 2155
Query: 654 FLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASK 711
+ P+ C C G LC L + C+ GL C L C A
Sbjct: 2156 RIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYS 2215
Query: 712 EYSPCVAPCGRTCQDLASPEACGVDGGDDLSR--DECVEGCACPPDTYLDTQADLCVPRN 769
Y+ C+ C +C DL DG + ++ C EGC C P L D CVPR+
Sbjct: 2216 SYTNCLPSCSPSCWDL--------DGRCEGAKVPSACAEGCICQPGYVL--SEDKCVPRS 2265
Query: 770 QCSC-HFQGVDYPPGDSDIPS--LGHCHCKDGVMSC-DSRAPAAA 810
QC C G P G S + S C C G + C D R P+ +
Sbjct: 2266 QCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQCGDFRCPSGS 2310
Score = 179 bits (454), Expect = 3e-44
Identities = 144/476 (30%), Positives = 196/476 (41%), Gaps = 63/476 (13%)
Query: 335 GWRTQLRQCTVHCKEKAFTYNECIACCPASCH-PRASCVDSEIACVDGCYCPNGLIFEDG 393
G T R T C A Y C CPASC PR SC C +GC C G +F D
Sbjct: 1032 GTTTTSRSSTERCPPNA-RYESC--ACPASCKSPRPSCGP---LCREGCVCNPGFLFSDN 1085
Query: 394 GCVAPAECPCEFHGTLYPPGSV-----VKEDCN------------------TCTCTSGKW 430
C+ + C C ++ Y PG+ E C C +G++
Sbjct: 1086 HCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQY 1145
Query: 431 ECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGT---FTVTLQNAPCGL 487
C A C V GD H+ TFDGR + F C YILA+ + T F VT +N G
Sbjct: 1146 GCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQG- 1204
Query: 488 NQDG-ACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRV 546
Q+G +C+ V V L P VTL + L+ Q +P + S F+ +
Sbjct: 1205 -QEGVSCLSKVYVTL---PESTVTLLKGRRTLVGGQQVTLPAIPSKGVFL-GASGRFVEL 1259
Query: 547 RTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGN 606
+T G+RV +D + +LY+ V + GLCG ++GN+ +D L G P + GN
Sbjct: 1260 QTEFGLRVRWDGD-QQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGN 1318
Query: 607 SWKT----LSACSPL-VSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVP 659
SW+T C V SP CD LQ++ C L T F C +
Sbjct: 1319 SWQTDQDEDQECQKYQVVNSP--SCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAAS 1376
Query: 660 YFEQCRRDAC--RCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCV 717
+F+ C D C + Q LC ++ C+ G V C ++C + +YS C
Sbjct: 1377 FFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCA 1436
Query: 718 APCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSC 773
PC TC S C D CVE C C P L C+PR+QC C
Sbjct: 1437 KPCPDTCHSGFSGMFCS---------DRCVEACECNPGFVLSGLE--CIPRSQCGC 1481
Score = 164 bits (414), Expect = 2e-39
Identities = 201/850 (23%), Positives = 306/850 (36%), Gaps = 170/850 (20%)
Query: 78 ICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS--FSIQV-HNDPQCGSSPYTCS 134
+C+ G+ H +FDG + + + LV P F I H + G+ +
Sbjct: 1930 VCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLH 1989
Query: 135 RAVSLFFVGEQEIHLAKEVTHGGMRVQLPHV--MGSARLQQLAGYVIVRHQSAFTLAWDG 192
+ + + V +V LP + + ++ + Y IV + + +DG
Sbjct: 1990 EVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDG 2049
Query: 193 ASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGP 252
+ I++ G G+CGN N + +D+L+ S ++ + EFV+SW+++ + P
Sbjct: 2050 NHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDID----P 2105
Query: 253 TTSSL-----PRPPCLQQNPG------TMQGVYEQCEALLRPPFDA-CHAYVSPLPFTAS 300
+ SL P Q+NP ++ E+CEA LR P A C + + PF
Sbjct: 2106 SCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVD 2165
Query: 301 CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 360
C + LC+ G C+AL + C G WR C + C + +Y C+
Sbjct: 2166 CANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNS-SFCPLECPAYS-SYTNCLPS 2223
Query: 361 CPASCHPR-ASCVDSEI--ACVDGCYCPNGLIFEDGGCVAPAECPC-EFHGTLYPPG-SV 415
C SC C +++ AC +GC C G + + CV ++C C + HG P G S
Sbjct: 2224 CSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSW 2283
Query: 416 VKEDCNT-CTCTSGKWECSTAVCPA---------------------ECSVTGDIHFTTFD 453
V C C CT G +C CP+ +CSV GD + TFD
Sbjct: 2284 VSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFD 2343
Query: 454 GRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTL-- 511
G Y Y+L K T+ P G+ + V+ + + PR + L
Sbjct: 2344 GFSYRLQGRMTYVLIK---------TVDVLPEGV--EPLLVEGRNKM--DPPRSSIFLQE 2390
Query: 512 -----------TQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREG 560
QAG L+ + K+ PY R N +RV G
Sbjct: 2391 VITTVYGYKVQLQAGLELVVNNQKMAVPY-----------------RPNEHLRVTL--WG 2431
Query: 561 LRLYLQVDQRWVED------------------TVGLCGTFNGNTQDDFLSPVGVPESTPQ 602
RLYL D V GLCG ++ N ++D + P G
Sbjct: 2432 QRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLN 2491
Query: 603 LFGNSWKTLS-------------------ACSPLVSGSPLDPCDVHLQAASYSVQACSVL 643
FGNSW+ + A L +G + C Q AS S QAC VL
Sbjct: 2492 TFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPE-QLASNSTQACRVL 2550
Query: 644 TGEM--FAPCSAFLSPVPYFEQCRRDACRCGQP-----CLCATLAHYAHLCRRH------ 690
FA C ++P P+ E C D C P C L+ + R H
Sbjct: 2551 ADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGHGVSSRYHISELYD 2610
Query: 691 -------------GLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDG 737
GL R RL C P +A CG T +
Sbjct: 2611 TLPSILCQPGRPRGLRGPLRGRLRQHPRLC-LQWHPEPPLADCGCTSNGIY------YQL 2663
Query: 738 GDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSC--HFQGV--DYPPGDSDIPSLGHC 793
G ++C + C C L + C C+ H QG + P + + G C
Sbjct: 2664 GSSFLTEDCSQRCTCASSRILLCEPFSCRAGEVCTLGNHTQGCFPESPCLQNPCQNDGQC 2723
Query: 794 HCKDGVMSCD 803
+ +C+
Sbjct: 2724 REQGATFTCE 2733
Score = 151 bits (382), Expect = 8e-36
Identities = 234/1057 (22%), Positives = 367/1057 (34%), Gaps = 223/1057 (21%)
Query: 1399 PTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEP 1458
PT T+P + PT S E+P + E P P+ +P + P P + + +
Sbjct: 584 PTVPKEKPTIPTEK--PTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPT 641
Query: 1459 VVSPGPTQTTLQQPLELTASQLPAGPTESPASKGV-TASLLAIPHTP-ESSSLP-----V 1511
+ S PT +T + P PTE P + T + + P P E S+P +
Sbjct: 642 IPSEKPTIST----------EKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSI 691
Query: 1512 ALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRT 1571
+ PT M + T + T+ SP P P + P +
Sbjct: 692 PTEKPTISMEETIISTEKPTI-------------SPEKPTIPTEKPTIPTEKSTISPEKP 738
Query: 1572 TPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQS--A 1629
T P T P+ +P SP PT TP IS + PT+ +
Sbjct: 739 TTPTEKPTI-PTEKPTISP----EKPT---------TPTEKPTISPEKLTIPTEKPTIPT 784
Query: 1630 SSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPP 1689
P+ P T T + + P +P E +STEK S PM P P S
Sbjct: 785 EKPTIP-TEKPTISTEEPTTPTE----ETTISTEKP----SIPMEKPTLPTEETTTSV-- 833
Query: 1690 RPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPL 1749
+ TT++T +P E P ++ST + T P++ + P ++P
Sbjct: 834 ---EETTISTEKLTIPMEKP---TISTE------------KPTIPTEKPTISPEKLTIPT 875
Query: 1750 AKVGTSAPVATPGPKASVITTPLQPQATTLPAQ--TLSPVLPFTPAAMTQAHPPTHIAPP 1807
K+ + T P + T + + T+P + T+SP P ++ P
Sbjct: 876 EKL----TIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKP----TISTEKP------- 920
Query: 1808 AAGTAPGLLLGATLPTSG-VLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGSA 1866
T+PT +P E T S + T K I +++++PT
Sbjct: 921 ------------TIPTEKPTIPTEETTISTEKLT---IPTEKPTISPEKLTIPTE----- 960
Query: 1867 EGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLA 1926
+ T +T P P L +PT T P + + L P
Sbjct: 961 -----KPTISTEKPTIPT----------EKLTIPTEKPTIPTEKPTIPTEKLTALRPP-- 1003
Query: 1927 EAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEA------------- 1973
H + LAA P S P S++ G ++TE
Sbjct: 1004 --HPSPTATGLAA-----LVMSPHAPSTPMTSVILGTTTTSRSSTERCPPNARYESCACP 1056
Query: 1974 ----NTSTTCVPIAEQDCV--------RHICLEG----------------QLIRVNQSQH 2005
+ +C P+ + CV + C++ + N ++H
Sbjct: 1057 ASCKSPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEH 1116
Query: 2006 C---PQGAAP---PRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFK 2059
C P +CG + G C + C ++ D +VTFDG H
Sbjct: 1117 CRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMG 1176
Query: 2060 EAIYILSQ----SPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRK 2115
+ YIL+Q S D V + + G CL + +T VT+ + R
Sbjct: 1177 KCTYILAQPCGNSTDPFFRVTAKNEEQGQEG-----VSCLSKVYVTLPESTVTLLKGRRT 1231
Query: 2116 VTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGL 2175
+ Q P + G + +G + T ++++W + V S T + GL
Sbjct: 1232 LVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRW-DGDQQLYVTVSSTYSGKLCGL 1290
Query: 2176 CGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSP- 2234
CG DG++ ND DGS G E+ +SWQ Q +++ + + D S
Sbjct: 1291 CGNYDGNSDNDHLKLDGSPAGDKEELG---NSWQTDQDEDQECQ-KYQVVNSPSCDSSLQ 1346
Query: 2235 --------CLRMV-SNRTFSACHRFVPPESFCELWIRDTKYVQ----QPCVALTVYVAMC 2281
C R+V ++ F C V SF + + D Q C ++ C
Sbjct: 1347 SSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTC 1406
Query: 2282 HKF-HVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCV 2340
H WR +CP C +S Y C C P TC G G + C E C
Sbjct: 1407 QDAGHAVKPWREPHFCPMACPPNSKYSLCAKPC--PDTCHSGFSGMFCSDRCV---EACE 1461
Query: 2341 CSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETW 2377
C+ G +L CIP ++C C G +GE W
Sbjct: 1462 CNPGFVL---SGLECIPRSQCGCLHPAGSYFKVGERW 1495
Score = 108 bits (269), Expect = 1e-22
Identities = 102/406 (25%), Positives = 158/406 (38%), Gaps = 63/406 (15%)
Query: 810 ACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFL 869
ACP + C+ D TC + S R C+ C C G + G C
Sbjct: 1425 ACPPNSKYSLCAKPCPD-------TCHSGFSGMFCSDR--CVEACECNPGFVLSGLECIP 1475
Query: 870 PEECPCTWKGKEYFP-GDQVMSP-C-HTCVCQRGS-FQCTLHPC---------------- 909
+C C YF G++ P C CVC+ + +C C
Sbjct: 1476 RSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCH 1535
Query: 910 ---ASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKS----TSDVSFSVIVENVN------ 956
A+TCTA GD HY TFDG F+G C L + + D F V N N
Sbjct: 1536 AQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILE 1595
Query: 957 -CYSSGMICRKF-ISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQE 1014
Y + F +SI++ V + P + + R+ ++ +
Sbjct: 1596 VSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTI---RLSSNLVLLYTNF 1652
Query: 1015 HITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAV 1074
+ + +D V V + GQL GLCGN++ ++++ P+ + + G++W
Sbjct: 1653 GLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAW--- 1709
Query: 1075 ECPDTLDPR--------DMCVLNPLREPFAKKECSILLSEV--FEICHPVVDVTWFYSNC 1124
+ P++ +P C N + + + K C+IL++ F CH VV +++C
Sbjct: 1710 KLPESSEPGCFLVGGKPSSCQENSMADAW-NKNCAILINPQGPFSQCHQVVPPQSSFASC 1768
Query: 1125 LTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDC 1170
+ CG GD C S+ AYA C Q G A WR CP C
Sbjct: 1769 VHGQCGTK--GDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRC 1812
Score = 107 bits (268), Expect = 1e-22
Identities = 100/406 (24%), Positives = 147/406 (36%), Gaps = 55/406 (13%)
Query: 804 SRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRH 863
SR+ CP + +C+ C + S C GC C G L
Sbjct: 1037 SRSSTERCPPNARYESCA-------------CPASCKSPRPSCGPLCREGCVCNPGFLFS 1083
Query: 864 GDACFLPEECPCTWKGKEYFPGDQVMSP--------------------CHT-CVCQRGSF 902
+ C C C + Y PG + SP C T VCQ +
Sbjct: 1084 DNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNG 1143
Query: 903 QCTLHPCA--STCTAYGDRHYRTFDGLPFDFVGACKVHLVK---STSDVSFSVIVENVNC 957
Q HP A +TC YGD HY TFDG F F+G C L + +++D F V +N
Sbjct: 1144 QYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQ 1203
Query: 958 YSSGMICRKFISINVGNSLIVFDDDS----GNPSPESFLDDKQEVHTWRVGFFTLVHFPQ 1013
G+ C + + + S + G + V G F + +
Sbjct: 1204 GQEGVSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQ-TE 1262
Query: 1014 EHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAA 1073
+ + WD ++V + G+L GLCGN+D + N+ + + +E G+SW
Sbjct: 1263 FGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQT 1322
Query: 1074 VECPDTLDPRDMCVLNPLREPFAKKE------CSILLSE--VFEICHPVVDVTWFYSNCL 1125
+ D + V +P + + C L+ FE C V F+ +C+
Sbjct: 1323 DQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCM 1382
Query: 1126 TDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1170
D CG G C +S C G AV WR P CP C
Sbjct: 1383 LDMCGFQ--GLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMAC 1426
Score = 93.2 bits (230), Expect = 3e-18
Identities = 93/378 (24%), Positives = 147/378 (38%), Gaps = 69/378 (18%)
Query: 2036 ACRCSIFPDLSFVTFDGSHVALFKEAIYIL-----SQSPDEMLTVHVLDCKSANLGHLNW 2090
A C+ D ++TFDG+ Y+L S+S D V + + +++
Sbjct: 1539 AATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSY 1598
Query: 2091 PPF---------------CLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIE 2135
C VMLN H+V + PVW R R+
Sbjct: 1599 IKAVHVTVFDLSISLLRGCKVMLN----GHRVAL------------PVWLAQGRVTIRL- 1641
Query: 2136 DTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLKDGS 2193
+ ++ ++ T +Q+++ G +VE + S G GLCG + ++ +D D
Sbjct: 1642 -SSNLVLLYTNFGLQVRY---DGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRK 1697
Query: 2194 VVGGAEDPAPFLDSWQVP-SSLTSVGQTRFRPDSCATTDCSP-----CLRMVSNR-TFSA 2246
+ G D +W++P SS +P SC + C +++ + FS
Sbjct: 1698 LAG---DSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQ 1754
Query: 2247 CHRFVPPESFCELWIR-------DTKYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFL 2299
CH+ VPP+S + DT + C +L Y ++C + WR +CP
Sbjct: 1755 CHQVVPPQSSFASCVHGQCGTKGDTTAL---CRSLQAYASLCAQAGQAPAWRNRTFCPMR 1811
Query: 2300 CSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEA 2359
C S+Y C + C P TC I P D E C C +G IL C+P
Sbjct: 1812 CPPGSSYSPCSSPC--PDTC-SSINNPRDCPKALPCAESCECQKGHIL---SGTSCVPLG 1865
Query: 2360 KCACTDSMGVPRALGETW 2377
+C CTD G +GE W
Sbjct: 1866 QCGCTDPAGSYHPVGERW 1883
Score = 80.5 bits (197), Expect = 2e-14
Identities = 107/485 (22%), Positives = 175/485 (36%), Gaps = 60/485 (12%)
Query: 1393 EPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPV 1452
+P V + ++ E + PT E+P +S E P P+ +P + P+ T P
Sbjct: 569 KPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNM-PSEKPTIPSEKPT 627
Query: 1453 TATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPA--SKGVTASLLAIPHTPESSSLP 1510
TE+P + + T+ +++ P PTE P ++ T S+ E S+P
Sbjct: 628 ILTEKPTIP--SEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIP 685
Query: 1511 -----VALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHG 1565
+ + PT M + T + T+ SP P P +
Sbjct: 686 TEKPSIPTEKPTISMEETIISTEKPTI-------------SPEKPTIPTEKPTIPTEKST 732
Query: 1566 SLPVRTTPPQPSLTASPSSRPVAS---PGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQ 1622
P + T P T P+ +P S P + PT S + T T + +P
Sbjct: 733 ISPEKPTTPTEKPTI-PTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPT 791
Query: 1623 PTQAQSASSPSTPLTVAGTAAEQ---------VPVSPLATRSLEIVLSTEKGEAGHSQPM 1673
S P+TP + E+ +P T E +STEK +P
Sbjct: 792 EKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPT 851
Query: 1674 GSPASPQ-PHPLPSAPPR----PAQHTTMATRSPALPPE--TPAAASLSTATDGLAATPF 1726
S P P P+ P P + T+ T P +P E T + L+ T+ +P
Sbjct: 852 ISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPE 911
Query: 1727 MSLESTRPSQLLSGLP----PDTSLPLAK--VGTSAPVATP--------GPKASVITTPL 1772
ST + + P +T++ K + T P +P P S +
Sbjct: 912 KPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTI 971
Query: 1773 QPQATTLPAQ--TLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVA 1830
+ T+P + T+ P P A P H +P A G A L++ P++ + V
Sbjct: 972 PTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLA-ALVMSPHAPSTPMTSVI 1030
Query: 1831 EGTAS 1835
GT +
Sbjct: 1031 LGTTT 1035
Score = 76.6 bits (187), Expect = 3e-13
Identities = 87/428 (20%), Positives = 153/428 (35%), Gaps = 88/428 (20%)
Query: 811 CPAGQVFVNCSDLHTDL--ELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACF 868
CP G + CS D ++ R C + L PC C C +G + G +C
Sbjct: 1812 CPPGSSYSPCSSPCPDTCSSINNPRDCPKAL---------PCAESCECQKGHILSGTSCV 1862
Query: 869 LPEECPCTWKGKEYFPGDQVMSPCHTCV----CQRGS----FQCTLHP------------ 908
+C CT Y P + +TC C + FQ T P
Sbjct: 1863 PLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLR 1922
Query: 909 CAST----CTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDV------------------ 946
C ++ C G+ HY +FDG AC + LVK
Sbjct: 1923 CRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGG 1982
Query: 947 --SFSVIVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVG 1004
+F + ++ Y + + +K + + + + S P + ++G
Sbjct: 1983 TEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIG 2042
Query: 1005 FFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNP 1064
+ + +D + ++ + G++ G+CGNF+ + +E+ P + +
Sbjct: 2043 -----------VQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSD 2091
Query: 1065 QEFGSSWAAVE----CPDTL------------DPRDMCVLNPLREPFAKKEC-SILLSEV 1107
EF +SW + C L +P C LR A+++C + L + V
Sbjct: 2092 SEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRR--AREKCEAALRAPV 2149
Query: 1108 FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVD-WRTPRLC 1166
+ C +D+T F +C C GG + C ++ A+ C G+ WR C
Sbjct: 2150 WAQCASRIDLTPFLVDCANTL--CEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFC 2207
Query: 1167 PYDCDFFN 1174
P +C ++
Sbjct: 2208 PLECPAYS 2215
Score = 76.3 bits (186), Expect = 4e-13
Identities = 77/322 (23%), Positives = 129/322 (40%), Gaps = 35/322 (10%)
Query: 2106 QVTIDRFNRKVTVDLQPVWPPVSRY-GFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEA 2164
QVT+ + +R + Q P +S+ G ++ + ++ +Q+++ + L+ +E
Sbjct: 1999 QVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKF-DGNHLLEIEI 2057
Query: 2165 SKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQV----PSSLTSVGQT 2220
T + G+CG + + ++L + V A + F++SW+ PS + +
Sbjct: 2058 PTTYYGKVCGMCGNFNDEEEDELMMPSDEV---ANSDSEFVNSWKDKDIDPSCQSLLVDE 2114
Query: 2221 RFRPDSCATTDCSPCLRMVSNRTFSACHRFV--PPESFCELWIRDTKYV----------- 2267
+ P C R C + P + C I T ++
Sbjct: 2115 QQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFG 2174
Query: 2268 ---QQPCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDG- 2322
Q C AL + A C + WR S +CP C + S+Y C+ +C P DG
Sbjct: 2175 GLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGR 2234
Query: 2323 ILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLS 2382
G P C EGC+C G +L C+P ++C C D+ G LG++W S S
Sbjct: 2235 CEGAKVPSAC---AEGCICQPGYVLSEDK---CVPRSQCGCKDAHGGSIPLGKSWVS--S 2286
Query: 2383 GCCQHQCQAPDTIVPVDLGCPS 2404
GC + I D CPS
Sbjct: 2287 GCTEKCVCTGGAIQCGDFRCPS 2308
Score = 75.1 bits (183), Expect = 9e-13
Identities = 93/442 (21%), Positives = 152/442 (34%), Gaps = 86/442 (19%)
Query: 61 TGPRCQMVY-----NAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHE--PEG 113
+G CQ+ N ++ C +G TFDG Y L G+ +Y L+ + PEG
Sbjct: 2308 SGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEG 2367
Query: 114 -QSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQ 172
+ ++ N S ++ + + ++ E+ ++ +P+
Sbjct: 2368 VEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRV 2427
Query: 173 QLAG---YVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGK 229
L G Y++ + +++ G I + G GLCGN + + K+D++ SG
Sbjct: 2428 TLWGQRLYLVTDFE--LVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGA 2485
Query: 230 LTDDVVEFVHSWQEQAPNQPPGPTTSSLPRP-PCLQQNPGTMQGV--------------- 273
LT ++ F +SW+ + + PR P ++ G G+
Sbjct: 2486 LTQNLNTFGNSWEVKTED-----ALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLA 2540
Query: 274 ---YEQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMG---DVATWCRALAEYA-- 323
+ C L P PF ACH V+P PF C DLC + C+ L+ +
Sbjct: 2541 SNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGHGVS 2600
Query: 324 -------------RACAQAGRP--LQG---------------WRTQLRQCTVHCKEKAFT 353
Q GRP L+G W + C
Sbjct: 2601 SRYHISELYDTLPSILCQPGRPRGLRGPLRGRLRQHPRLCLQWHPEPPLADCGCTSNGIY 2660
Query: 354 YNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDG----GCVAPAEC---PCEFH 406
Y + C R +C S I + C G + G GC + C PC+
Sbjct: 2661 YQLGSSFLTEDCSQRCTCASSRILLCEPFSCRAGEVCTLGNHTQGCFPESPCLQNPCQND 2720
Query: 407 GTLYPPGSVVKEDCNTCTCTSG 428
G G+ TC C G
Sbjct: 2721 GQCREQGATF-----TCECEVG 2737
Score = 74.7 bits (182), Expect = 1e-12
Identities = 109/472 (23%), Positives = 174/472 (36%), Gaps = 95/472 (20%)
Query: 1363 PRVEGCVPVCPTPQVLDEVTQRCVYLEDCVEPAVW--VPTEALGNETLPPSQGL------ 1414
P + P PT + + +E+ V P +PTE T P+ +
Sbjct: 647 PTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIIS 706
Query: 1415 ---PTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTTLQQ 1471
PT S E+P + E P PT + ++P P TT P TE+P +SP
Sbjct: 707 TEKPTISPEKPTIPTEKPTIPTEKSTISPEKP-TTPTEKPTIPTEKPTISP--------- 756
Query: 1472 PLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQT-PTPGMVSGAMETTRV 1530
+ P PTE P ++ L IP E ++P T PT E T
Sbjct: 757 -------EKPTTPTEKPT---ISPEKLTIP--TEKPTIPTEKPTIPTEKPTISTEEPTTP 804
Query: 1531 TVIFAGSPNITVSSRSP--PAPRFPLMTKAVTVRGHGSLPVRTTPPQPSLTASPSSRPVA 1588
T T+S+ P P + L T+ T T+ + +++ + P+
Sbjct: 805 T------EETTISTEKPSIPMEKPTLPTEETT----------TSVEETTISTEKLTIPME 848
Query: 1589 SPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTAAEQVPV 1648
P + PT + K ++P + + P+ LT+ T +P+
Sbjct: 849 KPTISTEKPTIP-TEKPTISP-----------------EKLTIPTEKLTIP-TEKPTIPI 889
Query: 1649 SPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPR-PAQHTTMATRSPALPPE 1707
+ ++ + TEK +P S P +P+ P P + TT++T +P E
Sbjct: 890 EETTISTEKLTIPTEKPTISPEKPTISTEKP---TIPTEKPTIPTEETTISTEKLTIPTE 946
Query: 1708 TPAAA--SLSTATDGLAATPFMSLES-TRPSQLLSGLPPDTSLPLAKVGTSAPVATPGPK 1764
P + L+ T+ P +S E T P++ L+ ++P K P K
Sbjct: 947 KPTISPEKLTIPTE----KPTISTEKPTIPTEKLTIPTEKPTIPTEK------PTIPTEK 996
Query: 1765 ASVITTP-LQPQATTLPAQTLSPVLPFTP------AAMTQAHPPTHIAPPAA 1809
+ + P P AT L A +SP P TP T + T PP A
Sbjct: 997 LTALRPPHPSPTATGLAALVMSPHAPSTPMTSVILGTTTTSRSSTERCPPNA 1048
Score = 70.9 bits (172), Expect = 2e-11
Identities = 90/382 (23%), Positives = 129/382 (33%), Gaps = 77/382 (20%)
Query: 811 CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLP 870
CPA + NC + + CE C GC C G + D C
Sbjct: 2211 CPAYSSYTNCLPSCSPSCWDLDGRCE------GAKVPSACAEGCICQPGYVLSEDKCVPR 2264
Query: 871 EECPC--TWKGKEYFPGDQVMSPC-HTCVCQRGSFQCTLHPCAS---------------- 911
+C C G V S C CVC G+ QC C S
Sbjct: 2265 SQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCV 2324
Query: 912 -----TCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSV---IVENVNCYS---S 960
C+ YGD Y TFDG + G L+K+ + V +VE N S
Sbjct: 2325 SDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRS 2384
Query: 961 GMICRKFIS--------INVGNSLIVFDDDSGNP-SPESFLDDKQEVHTWRVGFFTLVHF 1011
+ ++ I+ + G L+V + P P L V W + + F
Sbjct: 2385 SIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHL----RVTLWGQRLYLVTDF 2440
Query: 1012 PQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSW 1071
+ + + R + ++G ++GLCGN+D N+M P N FG+SW
Sbjct: 2441 ---ELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSW 2497
Query: 1072 AAVECPDTL--DPRDMCVLNP-------LREPFAKKECS------------ILLSE---V 1107
V+ D L PR + LR ECS +L++
Sbjct: 2498 -EVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGP 2556
Query: 1108 FEICHPVVDVTWFYSNCLTDTC 1129
F CH V F +C+ D C
Sbjct: 2557 FAACHQTVAPEPFQEHCVLDLC 2578
Score = 49.7 bits (117), Expect = 4e-05
Identities = 119/546 (21%), Positives = 192/546 (35%), Gaps = 107/546 (19%)
Query: 1954 APALSIVEGLAEALATTTEANTSTTCVP---IAEQDCVRHI---CLEGQLIRVNQSQHCP 2007
+P+ ++G E + C P ++E CV C + + +
Sbjct: 2225 SPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWV 2284
Query: 2008 QGAAPPRCGILGLAVRVGGDRCCPLWECAC---------------RCSIFPDLSFVTFDG 2052
+C G A++ G RC C +CS++ D ++TFDG
Sbjct: 2285 SSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDG 2344
Query: 2053 SHVALFKEAIYILSQSPDEMLT-VHVLDCKSANLGHLNWPPFCLVMLN---MTHLAHQVT 2108
L Y+L ++ D + V L + N PP + L T ++V
Sbjct: 2345 FSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMD---PPRSSIFLQEVITTVYGYKVQ 2401
Query: 2109 IDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTS 2168
+ V + + P R+ G ++T ++ + + +I S S
Sbjct: 2402 LQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVI---SLPS 2458
Query: 2169 KAQG--HGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQV-------------PSS 2213
+G GLCG D + ND+ L G++ ++ F +SW+V P+
Sbjct: 2459 MYEGLVSGLCGNYDKNRKNDMMLPSGALT---QNLNTFGNSWEVKTEDALLRFPRAIPAE 2515
Query: 2214 LTSVGQTRFRPDSCATTDCSPCLRMVSNRT------------FSACHRFVPPESFCELWI 2261
G ++CSP ++ SN T F+ACH+ V PE F E +
Sbjct: 2516 EEGQGAELGLRTGLQVSECSP-EQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCV 2574
Query: 2262 RDTKYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQD 2321
D Q P + + V + S+ L S C+P +
Sbjct: 2575 LDLCSAQDPREQEELRCQVLSGHGVSSRYHISELYDTLPS---------ILCQPGR--PR 2623
Query: 2322 GILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCI------PEAKCACTDSMGVPRALGE 2375
G+ GPL G + R+H LC+ P A C CT S G+ LG
Sbjct: 2624 GLRGPL---------------RGRL--RQHPRLCLQWHPEPPLADCGCT-SNGIYYQLG- 2664
Query: 2376 TWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCN 2435
+S L+ C +C + + L C P SC R GEV L C + C+ N
Sbjct: 2665 --SSFLTEDCSQRCTCASSRI---LLC---EPFSC-RAGEVCTLGNHTQGCFPESPCLQN 2715
Query: 2436 QTLCEG 2441
+G
Sbjct: 2716 PCQNDG 2721
Score = 32.7 bits (73), Expect = 5.3
Identities = 25/95 (26%), Positives = 33/95 (34%), Gaps = 19/95 (20%)
Query: 707 CEASKEYSPCVAPCGRTCQDLASPE-ACGVDGGDDLSRDECVEGCACPPDTYLDTQADLC 765
C + Y C P +C+ SP +CG C EGC C P C
Sbjct: 1044 CPPNARYESCACPA--SCK---SPRPSCG---------PLCREGCVCNPGFLFSDNH--C 1087
Query: 766 VPRNQCSCHFQGVDYPPGDS--DIPSLGHCHCKDG 798
+ + C+C + Y PG HC C G
Sbjct: 1088 IQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPG 1122
>gi|27881494 zonadhesin isoform 6 [Homo sapiens]
Length = 2721
Score = 230 bits (586), Expect = 2e-59
Identities = 201/752 (26%), Positives = 299/752 (39%), Gaps = 77/752 (10%)
Query: 79 CRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS----FSIQVHNDPQCGSSPYTCS 134
C +G H TFDG ++ GK +Y L +P G S F + N+ Q G +C
Sbjct: 1156 CLVYGDPHYVTFDGRHFGFMGKCTYILA---QPCGNSTDPFFRVTAKNEEQ-GQEGVSCL 1211
Query: 135 RAVSLFFVGEQEIHLAK--EVTHGGMRVQLPHVMGSARLQQLAG-YVIVRHQSAFTLAWD 191
V + + E + L K GG +V LP + +G +V ++ + + WD
Sbjct: 1212 SKVYVT-LPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWD 1270
Query: 192 GASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPG 251
G +Y+ +S G GLCGN + + +D + G D E +SWQ
Sbjct: 1271 GDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQEC 1330
Query: 252 PTTSSLPRPPCLQQNPGTMQGVYEQCEALL--RPPFDACHAYVSPLPFTASCTSDLCQSM 309
+ P C +M G C L+ PF+ C +V F SC D+C
Sbjct: 1331 QKYQVVNSPSCDSSLQSSMSGP-GFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQ 1389
Query: 310 GDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRA 369
G C ++ C AG ++ WR + C + C + Y+ C CP +CH
Sbjct: 1390 GLQHLLCTHMSTMTTTCQDAGHAVKPWR-EPHFCPMACPPNS-KYSLCAKPCPDTCHSGF 1447
Query: 370 SCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSV-------VKEDC-N 421
S + CV+ C C G + C+ ++C C L+P GS K C
Sbjct: 1448 SGMFCSDRCVEACECNPGFVLSGLECIPRSQCGC-----LHPAGSYFKVGERWYKPGCKE 1502
Query: 422 TCTCTSGK------WECST--------------AVCPAECSVTGDIHFTTFDGRRYTFPA 461
C C S W C A A C+ +GD H+ TFDG + F
Sbjct: 1503 LCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMG 1562
Query: 462 TCQYILAK---SRSSGT-FTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDV 517
TC Y+L + SRS + F V+ N G + + +++V V + ++L + V
Sbjct: 1563 TCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFD---LSISLLRGCKV 1619
Query: 518 LLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVG 577
+L +P + RLSS + + TN G++V YD L + + V + G
Sbjct: 1620 MLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHL-VEVTVPSSYGGQLCG 1678
Query: 578 LCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSP---LVSGSPLDPCDVHLQAAS 634
LCG +N N+ DD L P G +WK + P LV G P C + A +
Sbjct: 1679 LCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKP-SSCQENSMADA 1737
Query: 635 YSVQACSVLTGEM--FAPCSAFLSPVPYFEQCRRDAC--RCGQPCLCATLAHYAHLCRRH 690
++ + C++L F+ C + P F C C + LC +L YA LC +
Sbjct: 1738 WN-KNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQA 1796
Query: 691 GLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGC 750
G +R R C + C YSPC +PC TC + +P C C E C
Sbjct: 1797 GQAPAWRNR-TFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCP-------KALPCAESC 1848
Query: 751 ACPPDTYLDTQADLCVPRNQCSCHFQGVDYPP 782
C L + CVP QC C Y P
Sbjct: 1849 ECQKGHILSGTS--CVPLGQCGCTDPAGSYHP 1878
Score = 224 bits (570), Expect = 1e-57
Identities = 218/885 (24%), Positives = 348/885 (39%), Gaps = 127/885 (14%)
Query: 25 ERRLHRAKCAPSYLFS---CFNGGEC--VHPA-----------------FCDCRRFNATG 62
+R + +C P ++ S C +C +HPA C C N
Sbjct: 1454 DRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRI- 1512
Query: 63 PRCQM--------------VYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGR 108
RCQ +Y + + C A G H TFDG ++ G +Y L
Sbjct: 1513 -RCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRP 1571
Query: 109 HEPEGQS--FSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAK--EVTHGGMRVQLPH 164
Q F + N+ + G + +AV + V + I L + +V G RV LP
Sbjct: 1572 CWSRSQDSYFVVSATNENRGGILEVSYIKAVHVT-VFDLSISLLRGCKVMLNGHRVALPV 1630
Query: 165 VMGSAR--LQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDD 222
+ R ++ + V++ + +DG+ V + + G GLCGN N + DD
Sbjct: 1631 WLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDD 1690
Query: 223 LVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQ-CEALL 281
+ KL D ++ +W+ ++P +P Q+N +M + + C L+
Sbjct: 1691 NLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGG--KPSSCQEN--SMADAWNKNCAILI 1746
Query: 282 RP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQ 339
P PF CH V P ASC C + GD CR+L YA CAQAG+ WR +
Sbjct: 1747 NPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQ-APAWRNR 1805
Query: 340 LRQCTVHCKEKAFTYNECIACCPASC----HPRASCVDSEIACVDGCYCPNGLIFEDGGC 395
C + C + +Y+ C + CP +C +PR C + C + C C G I C
Sbjct: 1806 -TFCPMRCPPGS-SYSPCSSPCPDTCSSINNPR-DC-PKALPCAESCECQKGHILSGTSC 1861
Query: 396 VAPAECPC-EFHGTLYPPGS--VVKEDC-NTCTCT-SGKWECSTAVCPAE---------- 440
V +C C + G+ +P G + C CTC+ C + C
Sbjct: 1862 VPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLL 1921
Query: 441 ---------CSVTGDIHFTTFDGRRYTFPATCQYILAK----SRSSGTFTVTLQNAPCGL 487
C + G+ H+ +FDG ++ P C +L K + + F ++ ++
Sbjct: 1922 RCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEG 1981
Query: 488 NQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVR 547
+ + V + ++ QVTL + VL+ + +P + + SS++ V
Sbjct: 1982 GTEAFRLHEVYIDIYD---AQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVN 2038
Query: 548 TNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNS 607
+GV+V +D L L +++ + G+CG FN +D+ + P ++ F NS
Sbjct: 2039 IKIGVQVKFDGNHL-LEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNS 2097
Query: 608 WKTLS---ACSPLVSGSPLDPCD-----------VHLQAASYSVQACSVLTGEMFAPCSA 653
WK +C L+ P + L+ A +A L ++A C++
Sbjct: 2098 WKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEA--ALRAPVWAQCAS 2155
Query: 654 FLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASK 711
+ P+ C C G LC L + C+ GL C L C A
Sbjct: 2156 RIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYS 2215
Query: 712 EYSPCVAPCGRTCQDLASPEACGVDGGDDLSR--DECVEGCACPPDTYLDTQADLCVPRN 769
Y+ C+ C +C DL DG + ++ C EGC C P L D CVPR+
Sbjct: 2216 SYTNCLPSCSPSCWDL--------DGRCEGAKVPSACAEGCICQPGYVL--SEDKCVPRS 2265
Query: 770 QCSC-HFQGVDYPPGDSDIPS--LGHCHCKDGVMSC-DSRAPAAA 810
QC C G P G S + S C C G + C D R P+ +
Sbjct: 2266 QCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQCGDFRCPSGS 2310
Score = 179 bits (454), Expect = 3e-44
Identities = 144/476 (30%), Positives = 196/476 (41%), Gaps = 63/476 (13%)
Query: 335 GWRTQLRQCTVHCKEKAFTYNECIACCPASCH-PRASCVDSEIACVDGCYCPNGLIFEDG 393
G T R T C A Y C CPASC PR SC C +GC C G +F D
Sbjct: 1032 GTTTTSRSSTERCPPNA-RYESC--ACPASCKSPRPSCGP---LCREGCVCNPGFLFSDN 1085
Query: 394 GCVAPAECPCEFHGTLYPPGSV-----VKEDCN------------------TCTCTSGKW 430
C+ + C C ++ Y PG+ E C C +G++
Sbjct: 1086 HCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQY 1145
Query: 431 ECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGT---FTVTLQNAPCGL 487
C A C V GD H+ TFDGR + F C YILA+ + T F VT +N G
Sbjct: 1146 GCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQG- 1204
Query: 488 NQDG-ACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRV 546
Q+G +C+ V V L P VTL + L+ Q +P + S F+ +
Sbjct: 1205 -QEGVSCLSKVYVTL---PESTVTLLKGRRTLVGGQQVTLPAIPSKGVFL-GASGRFVEL 1259
Query: 547 RTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGN 606
+T G+RV +D + +LY+ V + GLCG ++GN+ +D L G P + GN
Sbjct: 1260 QTEFGLRVRWDGD-QQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGN 1318
Query: 607 SWKT----LSACSPL-VSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVP 659
SW+T C V SP CD LQ++ C L T F C +
Sbjct: 1319 SWQTDQDEDQECQKYQVVNSP--SCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAAS 1376
Query: 660 YFEQCRRDAC--RCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCV 717
+F+ C D C + Q LC ++ C+ G V C ++C + +YS C
Sbjct: 1377 FFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCA 1436
Query: 718 APCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSC 773
PC TC S C D CVE C C P L C+PR+QC C
Sbjct: 1437 KPCPDTCHSGFSGMFCS---------DRCVEACECNPGFVLSGLE--CIPRSQCGC 1481
Score = 168 bits (426), Expect = 6e-41
Identities = 195/782 (24%), Positives = 295/782 (37%), Gaps = 156/782 (19%)
Query: 78 ICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS--FSIQV-HNDPQCGSSPYTCS 134
+C+ G+ H +FDG + + + LV P F I H + G+ +
Sbjct: 1930 VCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLH 1989
Query: 135 RAVSLFFVGEQEIHLAKEVTHGGMRVQLPHV--MGSARLQQLAGYVIVRHQSAFTLAWDG 192
+ + + V +V LP + + ++ + Y IV + + +DG
Sbjct: 1990 EVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDG 2049
Query: 193 ASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGP 252
+ I++ G G+CGN N + +D+L+ S ++ + EFV+SW+++ + P
Sbjct: 2050 NHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDID----P 2105
Query: 253 TTSSL-----PRPPCLQQNPG------TMQGVYEQCEALLRPPFDA-CHAYVSPLPFTAS 300
+ SL P Q+NP ++ E+CEA LR P A C + + PF
Sbjct: 2106 SCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVD 2165
Query: 301 CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 360
C + LC+ G C+AL + C G WR C + C + +Y C+
Sbjct: 2166 CANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNS-SFCPLECPAYS-SYTNCLPS 2223
Query: 361 CPASCHPR-ASCVDSEI--ACVDGCYCPNGLIFEDGGCVAPAECPC-EFHGTLYPPG-SV 415
C SC C +++ AC +GC C G + + CV ++C C + HG P G S
Sbjct: 2224 CSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSW 2283
Query: 416 VKEDCNT-CTCTSGKWECSTAVCPA---------------------ECSVTGDIHFTTFD 453
V C C CT G +C CP+ +CSV GD + TFD
Sbjct: 2284 VSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFD 2343
Query: 454 GRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTL-- 511
G Y Y+L K T+ P G+ + V+ + + PR + L
Sbjct: 2344 GFSYRLQGRMTYVLIK---------TVDVLPEGV--EPLLVEGRNKM--DPPRSSIFLQE 2390
Query: 512 -----------TQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREG 560
QAG L+ + K+ PY R N +RV G
Sbjct: 2391 VITTVYGYKVQLQAGLELVVNNQKMAVPY-----------------RPNEHLRVTL--WG 2431
Query: 561 LRLYLQVDQRWVED------------------TVGLCGTFNGNTQDDFLSPVGVPESTPQ 602
RLYL D V GLCG ++ N ++D + P G
Sbjct: 2432 QRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLN 2491
Query: 603 LFGNSWKTLS-------------------ACSPLVSGSPLDPCDVHLQAASYSVQACSVL 643
FGNSW+ + A L +G + C Q AS S QAC VL
Sbjct: 2492 TFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPE-QLASNSTQACRVL 2550
Query: 644 TGEM--FAPCSAFLSPVPYFEQCRRDACRCGQP-----CLCATLAHYAHLCRRHGLPV-D 695
FA C ++P P+ E C D C P C L+ YA LC+ G +
Sbjct: 2551 ADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAG 2610
Query: 696 FRARLPACALSCEASKEYSPCVA-PCGR--TCQDLASPEACGVDGGDDLSRDECVEGCAC 752
+R R CE SPC+ PC C++ + C + G C+E
Sbjct: 2611 WRDR-----TLCE-----SPCLQNPCQNDGQCREQGATFTCECEVG--YGGGLCMEPRDA 2658
Query: 753 PP 754
PP
Sbjct: 2659 PP 2660
Score = 151 bits (382), Expect = 8e-36
Identities = 234/1057 (22%), Positives = 367/1057 (34%), Gaps = 223/1057 (21%)
Query: 1399 PTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEP 1458
PT T+P + PT S E+P + E P P+ +P + P P + + +
Sbjct: 584 PTVPKEKPTIPTEK--PTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPT 641
Query: 1459 VVSPGPTQTTLQQPLELTASQLPAGPTESPASKGV-TASLLAIPHTP-ESSSLP-----V 1511
+ S PT +T + P PTE P + T + + P P E S+P +
Sbjct: 642 IPSEKPTIST----------EKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSI 691
Query: 1512 ALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRT 1571
+ PT M + T + T+ SP P P + P +
Sbjct: 692 PTEKPTISMEETIISTEKPTI-------------SPEKPTIPTEKPTIPTEKSTISPEKP 738
Query: 1572 TPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQS--A 1629
T P T P+ +P SP PT TP IS + PT+ +
Sbjct: 739 TTPTEKPTI-PTEKPTISP----EKPT---------TPTEKPTISPEKLTIPTEKPTIPT 784
Query: 1630 SSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPP 1689
P+ P T T + + P +P E +STEK S PM P P S
Sbjct: 785 EKPTIP-TEKPTISTEEPTTPTE----ETTISTEKP----SIPMEKPTLPTEETTTSV-- 833
Query: 1690 RPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPL 1749
+ TT++T +P E P ++ST + T P++ + P ++P
Sbjct: 834 ---EETTISTEKLTIPMEKP---TISTE------------KPTIPTEKPTISPEKLTIPT 875
Query: 1750 AKVGTSAPVATPGPKASVITTPLQPQATTLPAQ--TLSPVLPFTPAAMTQAHPPTHIAPP 1807
K+ + T P + T + + T+P + T+SP P ++ P
Sbjct: 876 EKL----TIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKP----TISTEKP------- 920
Query: 1808 AAGTAPGLLLGATLPTSG-VLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGSA 1866
T+PT +P E T S + T K I +++++PT
Sbjct: 921 ------------TIPTEKPTIPTEETTISTEKLT---IPTEKPTISPEKLTIPTE----- 960
Query: 1867 EGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLA 1926
+ T +T P P L +PT T P + + L P
Sbjct: 961 -----KPTISTEKPTIPT----------EKLTIPTEKPTIPTEKPTIPTEKLTALRPP-- 1003
Query: 1927 EAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEA------------- 1973
H + LAA P S P S++ G ++TE
Sbjct: 1004 --HPSPTATGLAA-----LVMSPHAPSTPMTSVILGTTTTSRSSTERCPPNARYESCACP 1056
Query: 1974 ----NTSTTCVPIAEQDCV--------RHICLEG----------------QLIRVNQSQH 2005
+ +C P+ + CV + C++ + N ++H
Sbjct: 1057 ASCKSPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEH 1116
Query: 2006 C---PQGAAP---PRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFK 2059
C P +CG + G C + C ++ D +VTFDG H
Sbjct: 1117 CRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMG 1176
Query: 2060 EAIYILSQ----SPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRK 2115
+ YIL+Q S D V + + G CL + +T VT+ + R
Sbjct: 1177 KCTYILAQPCGNSTDPFFRVTAKNEEQGQEG-----VSCLSKVYVTLPESTVTLLKGRRT 1231
Query: 2116 VTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGL 2175
+ Q P + G + +G + T ++++W + V S T + GL
Sbjct: 1232 LVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRW-DGDQQLYVTVSSTYSGKLCGL 1290
Query: 2176 CGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSP- 2234
CG DG++ ND DGS G E+ +SWQ Q +++ + + D S
Sbjct: 1291 CGNYDGNSDNDHLKLDGSPAGDKEELG---NSWQTDQDEDQECQ-KYQVVNSPSCDSSLQ 1346
Query: 2235 --------CLRMV-SNRTFSACHRFVPPESFCELWIRDTKYVQ----QPCVALTVYVAMC 2281
C R+V ++ F C V SF + + D Q C ++ C
Sbjct: 1347 SSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTC 1406
Query: 2282 HKF-HVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCV 2340
H WR +CP C +S Y C C P TC G G + C E C
Sbjct: 1407 QDAGHAVKPWREPHFCPMACPPNSKYSLCAKPC--PDTCHSGFSGMFCSDRCV---EACE 1461
Query: 2341 CSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETW 2377
C+ G +L CIP ++C C G +GE W
Sbjct: 1462 CNPGFVL---SGLECIPRSQCGCLHPAGSYFKVGERW 1495
Score = 108 bits (269), Expect = 1e-22
Identities = 102/406 (25%), Positives = 158/406 (38%), Gaps = 63/406 (15%)
Query: 810 ACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFL 869
ACP + C+ D TC + S R C+ C C G + G C
Sbjct: 1425 ACPPNSKYSLCAKPCPD-------TCHSGFSGMFCSDR--CVEACECNPGFVLSGLECIP 1475
Query: 870 PEECPCTWKGKEYFP-GDQVMSP-C-HTCVCQRGS-FQCTLHPC---------------- 909
+C C YF G++ P C CVC+ + +C C
Sbjct: 1476 RSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCH 1535
Query: 910 ---ASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKS----TSDVSFSVIVENVN------ 956
A+TCTA GD HY TFDG F+G C L + + D F V N N
Sbjct: 1536 AQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILE 1595
Query: 957 -CYSSGMICRKF-ISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQE 1014
Y + F +SI++ V + P + + R+ ++ +
Sbjct: 1596 VSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTI---RLSSNLVLLYTNF 1652
Query: 1015 HITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAV 1074
+ + +D V V + GQL GLCGN++ ++++ P+ + + G++W
Sbjct: 1653 GLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAW--- 1709
Query: 1075 ECPDTLDPR--------DMCVLNPLREPFAKKECSILLSEV--FEICHPVVDVTWFYSNC 1124
+ P++ +P C N + + + K C+IL++ F CH VV +++C
Sbjct: 1710 KLPESSEPGCFLVGGKPSSCQENSMADAW-NKNCAILINPQGPFSQCHQVVPPQSSFASC 1768
Query: 1125 LTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDC 1170
+ CG GD C S+ AYA C Q G A WR CP C
Sbjct: 1769 VHGQCGTK--GDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRC 1812
Score = 107 bits (268), Expect = 1e-22
Identities = 100/406 (24%), Positives = 147/406 (36%), Gaps = 55/406 (13%)
Query: 804 SRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRH 863
SR+ CP + +C+ C + S C GC C G L
Sbjct: 1037 SRSSTERCPPNARYESCA-------------CPASCKSPRPSCGPLCREGCVCNPGFLFS 1083
Query: 864 GDACFLPEECPCTWKGKEYFPGDQVMSP--------------------CHT-CVCQRGSF 902
+ C C C + Y PG + SP C T VCQ +
Sbjct: 1084 DNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNG 1143
Query: 903 QCTLHPCA--STCTAYGDRHYRTFDGLPFDFVGACKVHLVK---STSDVSFSVIVENVNC 957
Q HP A +TC YGD HY TFDG F F+G C L + +++D F V +N
Sbjct: 1144 QYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQ 1203
Query: 958 YSSGMICRKFISINVGNSLIVFDDDS----GNPSPESFLDDKQEVHTWRVGFFTLVHFPQ 1013
G+ C + + + S + G + V G F + +
Sbjct: 1204 GQEGVSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQ-TE 1262
Query: 1014 EHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAA 1073
+ + WD ++V + G+L GLCGN+D + N+ + + +E G+SW
Sbjct: 1263 FGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQT 1322
Query: 1074 VECPDTLDPRDMCVLNPLREPFAKKE------CSILLSE--VFEICHPVVDVTWFYSNCL 1125
+ D + V +P + + C L+ FE C V F+ +C+
Sbjct: 1323 DQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCM 1382
Query: 1126 TDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1170
D CG G C +S C G AV WR P CP C
Sbjct: 1383 LDMCGFQ--GLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMAC 1426
Score = 93.2 bits (230), Expect = 3e-18
Identities = 93/378 (24%), Positives = 147/378 (38%), Gaps = 69/378 (18%)
Query: 2036 ACRCSIFPDLSFVTFDGSHVALFKEAIYIL-----SQSPDEMLTVHVLDCKSANLGHLNW 2090
A C+ D ++TFDG+ Y+L S+S D V + + +++
Sbjct: 1539 AATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSY 1598
Query: 2091 PPF---------------CLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIE 2135
C VMLN H+V + PVW R R+
Sbjct: 1599 IKAVHVTVFDLSISLLRGCKVMLN----GHRVAL------------PVWLAQGRVTIRL- 1641
Query: 2136 DTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLKDGS 2193
+ ++ ++ T +Q+++ G +VE + S G GLCG + ++ +D D
Sbjct: 1642 -SSNLVLLYTNFGLQVRY---DGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRK 1697
Query: 2194 VVGGAEDPAPFLDSWQVP-SSLTSVGQTRFRPDSCATTDCSP-----CLRMVSNR-TFSA 2246
+ G D +W++P SS +P SC + C +++ + FS
Sbjct: 1698 LAG---DSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQ 1754
Query: 2247 CHRFVPPESFCELWIR-------DTKYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFL 2299
CH+ VPP+S + DT + C +L Y ++C + WR +CP
Sbjct: 1755 CHQVVPPQSSFASCVHGQCGTKGDTTAL---CRSLQAYASLCAQAGQAPAWRNRTFCPMR 1811
Query: 2300 CSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEA 2359
C S+Y C + C P TC I P D E C C +G IL C+P
Sbjct: 1812 CPPGSSYSPCSSPC--PDTC-SSINNPRDCPKALPCAESCECQKGHIL---SGTSCVPLG 1865
Query: 2360 KCACTDSMGVPRALGETW 2377
+C CTD G +GE W
Sbjct: 1866 QCGCTDPAGSYHPVGERW 1883
Score = 86.3 bits (212), Expect = 4e-16
Identities = 86/377 (22%), Positives = 141/377 (37%), Gaps = 60/377 (15%)
Query: 61 TGPRCQMVY-----NAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHE--PEG 113
+G CQ+ N ++ C +G TFDG Y L G+ +Y L+ + PEG
Sbjct: 2308 SGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEG 2367
Query: 114 -QSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQ 172
+ ++ N S ++ + + ++ E+ ++ +P+
Sbjct: 2368 VEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRV 2427
Query: 173 QLAG---YVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGK 229
L G Y++ + +++ G I + G GLCGN + + K+D++ SG
Sbjct: 2428 TLWGQRLYLVTDFE--LVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGA 2485
Query: 230 LTDDVVEFVHSWQEQAPNQPPGPTTSSLPRP-PCLQQNPGTMQGV--------------- 273
LT ++ F +SW+ + + PR P ++ G G+
Sbjct: 2486 LTQNLNTFGNSWEVKTED-----ALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLA 2540
Query: 274 ---YEQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMG---DVATWCRALAEYARA 325
+ C L P PF ACH V+P PF C DLC + C+ L+ YA
Sbjct: 2541 SNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAIL 2600
Query: 326 CAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCP 385
C +AG L GWR + C+ C C C E C C
Sbjct: 2601 CQEAGAALAGWRDR-----TLCES---------PCLQNPCQNDGQC--REQGATFTCECE 2644
Query: 386 NGLIFEDGGCVAPAECP 402
G + G C+ P + P
Sbjct: 2645 VG--YGGGLCMEPRDAP 2659
Score = 84.3 bits (207), Expect = 2e-15
Identities = 103/425 (24%), Positives = 146/425 (34%), Gaps = 79/425 (18%)
Query: 811 CPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLP 870
CPA + NC + + CE C GC C G + D C
Sbjct: 2211 CPAYSSYTNCLPSCSPSCWDLDGRCE------GAKVPSACAEGCICQPGYVLSEDKCVPR 2264
Query: 871 EECPC--TWKGKEYFPGDQVMSPC-HTCVCQRGSFQCTLHPCAS---------------- 911
+C C G V S C CVC G+ QC C S
Sbjct: 2265 SQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCV 2324
Query: 912 -----TCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSV---IVENVNCYS---S 960
C+ YGD Y TFDG + G L+K+ + V +VE N S
Sbjct: 2325 SDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRS 2384
Query: 961 GMICRKFIS--------INVGNSLIVFDDDSGNP-SPESFLDDKQEVHTWRVGFFTLVHF 1011
+ ++ I+ + G L+V + P P L V W + + F
Sbjct: 2385 SIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHL----RVTLWGQRLYLVTDF 2440
Query: 1012 PQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSW 1071
+ + + R + ++G ++GLCGN+D N+M P N FG+SW
Sbjct: 2441 ---ELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSW 2497
Query: 1072 AAVECPDTL--DPRDMCVLNP-------LREPFAKKECS------------ILLSE---V 1107
V+ D L PR + LR ECS +L++
Sbjct: 2498 -EVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGP 2556
Query: 1108 FEICHPVVDVTWFYSNCLTDTCGCSQGGDC-ECFCASVSAYAHQCCQHGVAV-DWRTPRL 1165
F CH V F +C+ D C + E C +S YA C + G A+ WR L
Sbjct: 2557 FAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTL 2616
Query: 1166 CPYDC 1170
C C
Sbjct: 2617 CESPC 2621
Score = 80.5 bits (197), Expect = 2e-14
Identities = 107/485 (22%), Positives = 175/485 (36%), Gaps = 60/485 (12%)
Query: 1393 EPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPV 1452
+P V + ++ E + PT E+P +S E P P+ +P + P+ T P
Sbjct: 569 KPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNM-PSEKPTIPSEKPT 627
Query: 1453 TATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPA--SKGVTASLLAIPHTPESSSLP 1510
TE+P + + T+ +++ P PTE P ++ T S+ E S+P
Sbjct: 628 ILTEKPTIP--SEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIP 685
Query: 1511 -----VALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHG 1565
+ + PT M + T + T+ SP P P +
Sbjct: 686 TEKPSIPTEKPTISMEETIISTEKPTI-------------SPEKPTIPTEKPTIPTEKST 732
Query: 1566 SLPVRTTPPQPSLTASPSSRPVAS---PGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQ 1622
P + T P T P+ +P S P + PT S + T T + +P
Sbjct: 733 ISPEKPTTPTEKPTI-PTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPT 791
Query: 1623 PTQAQSASSPSTPLTVAGTAAEQ---------VPVSPLATRSLEIVLSTEKGEAGHSQPM 1673
S P+TP + E+ +P T E +STEK +P
Sbjct: 792 EKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPT 851
Query: 1674 GSPASPQ-PHPLPSAPPR----PAQHTTMATRSPALPPE--TPAAASLSTATDGLAATPF 1726
S P P P+ P P + T+ T P +P E T + L+ T+ +P
Sbjct: 852 ISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPE 911
Query: 1727 MSLESTRPSQLLSGLP----PDTSLPLAK--VGTSAPVATP--------GPKASVITTPL 1772
ST + + P +T++ K + T P +P P S +
Sbjct: 912 KPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTI 971
Query: 1773 QPQATTLPAQ--TLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVA 1830
+ T+P + T+ P P A P H +P A G A L++ P++ + V
Sbjct: 972 PTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLA-ALVMSPHAPSTPMTSVI 1030
Query: 1831 EGTAS 1835
GT +
Sbjct: 1031 LGTTT 1035
Score = 76.6 bits (187), Expect = 3e-13
Identities = 87/428 (20%), Positives = 153/428 (35%), Gaps = 88/428 (20%)
Query: 811 CPAGQVFVNCSDLHTDL--ELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACF 868
CP G + CS D ++ R C + L PC C C +G + G +C
Sbjct: 1812 CPPGSSYSPCSSPCPDTCSSINNPRDCPKAL---------PCAESCECQKGHILSGTSCV 1862
Query: 869 LPEECPCTWKGKEYFPGDQVMSPCHTCV----CQRGS----FQCTLHP------------ 908
+C CT Y P + +TC C + FQ T P
Sbjct: 1863 PLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLR 1922
Query: 909 CAST----CTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDV------------------ 946
C ++ C G+ HY +FDG AC + LVK
Sbjct: 1923 CRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGG 1982
Query: 947 --SFSVIVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVG 1004
+F + ++ Y + + +K + + + + S P + ++G
Sbjct: 1983 TEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIG 2042
Query: 1005 FFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNP 1064
+ + +D + ++ + G++ G+CGNF+ + +E+ P + +
Sbjct: 2043 -----------VQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSD 2091
Query: 1065 QEFGSSWAAVE----CPDTL------------DPRDMCVLNPLREPFAKKEC-SILLSEV 1107
EF +SW + C L +P C LR A+++C + L + V
Sbjct: 2092 SEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRR--AREKCEAALRAPV 2149
Query: 1108 FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVD-WRTPRLC 1166
+ C +D+T F +C C GG + C ++ A+ C G+ WR C
Sbjct: 2150 WAQCASRIDLTPFLVDCANTL--CEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFC 2207
Query: 1167 PYDCDFFN 1174
P +C ++
Sbjct: 2208 PLECPAYS 2215
Score = 76.3 bits (186), Expect = 4e-13
Identities = 77/322 (23%), Positives = 129/322 (40%), Gaps = 35/322 (10%)
Query: 2106 QVTIDRFNRKVTVDLQPVWPPVSRY-GFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEA 2164
QVT+ + +R + Q P +S+ G ++ + ++ +Q+++ + L+ +E
Sbjct: 1999 QVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKF-DGNHLLEIEI 2057
Query: 2165 SKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQV----PSSLTSVGQT 2220
T + G+CG + + ++L + V A + F++SW+ PS + +
Sbjct: 2058 PTTYYGKVCGMCGNFNDEEEDELMMPSDEV---ANSDSEFVNSWKDKDIDPSCQSLLVDE 2114
Query: 2221 RFRPDSCATTDCSPCLRMVSNRTFSACHRFV--PPESFCELWIRDTKYV----------- 2267
+ P C R C + P + C I T ++
Sbjct: 2115 QQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFG 2174
Query: 2268 ---QQPCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDG- 2322
Q C AL + A C + WR S +CP C + S+Y C+ +C P DG
Sbjct: 2175 GLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGR 2234
Query: 2323 ILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLS 2382
G P C EGC+C G +L C+P ++C C D+ G LG++W S S
Sbjct: 2235 CEGAKVPSAC---AEGCICQPGYVLSEDK---CVPRSQCGCKDAHGGSIPLGKSWVS--S 2286
Query: 2383 GCCQHQCQAPDTIVPVDLGCPS 2404
GC + I D CPS
Sbjct: 2287 GCTEKCVCTGGAIQCGDFRCPS 2308
Score = 74.7 bits (182), Expect = 1e-12
Identities = 109/472 (23%), Positives = 174/472 (36%), Gaps = 95/472 (20%)
Query: 1363 PRVEGCVPVCPTPQVLDEVTQRCVYLEDCVEPAVW--VPTEALGNETLPPSQGL------ 1414
P + P PT + + +E+ V P +PTE T P+ +
Sbjct: 647 PTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIIS 706
Query: 1415 ---PTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTTLQQ 1471
PT S E+P + E P PT + ++P P TT P TE+P +SP
Sbjct: 707 TEKPTISPEKPTIPTEKPTIPTEKSTISPEKP-TTPTEKPTIPTEKPTISP--------- 756
Query: 1472 PLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQT-PTPGMVSGAMETTRV 1530
+ P PTE P ++ L IP E ++P T PT E T
Sbjct: 757 -------EKPTTPTEKPT---ISPEKLTIP--TEKPTIPTEKPTIPTEKPTISTEEPTTP 804
Query: 1531 TVIFAGSPNITVSSRSP--PAPRFPLMTKAVTVRGHGSLPVRTTPPQPSLTASPSSRPVA 1588
T T+S+ P P + L T+ T T+ + +++ + P+
Sbjct: 805 T------EETTISTEKPSIPMEKPTLPTEETT----------TSVEETTISTEKLTIPME 848
Query: 1589 SPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTAAEQVPV 1648
P + PT + K ++P + + P+ LT+ T +P+
Sbjct: 849 KPTISTEKPTIP-TEKPTISP-----------------EKLTIPTEKLTIP-TEKPTIPI 889
Query: 1649 SPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPR-PAQHTTMATRSPALPPE 1707
+ ++ + TEK +P S P +P+ P P + TT++T +P E
Sbjct: 890 EETTISTEKLTIPTEKPTISPEKPTISTEKP---TIPTEKPTIPTEETTISTEKLTIPTE 946
Query: 1708 TPAAA--SLSTATDGLAATPFMSLES-TRPSQLLSGLPPDTSLPLAKVGTSAPVATPGPK 1764
P + L+ T+ P +S E T P++ L+ ++P K P K
Sbjct: 947 KPTISPEKLTIPTE----KPTISTEKPTIPTEKLTIPTEKPTIPTEK------PTIPTEK 996
Query: 1765 ASVITTP-LQPQATTLPAQTLSPVLPFTP------AAMTQAHPPTHIAPPAA 1809
+ + P P AT L A +SP P TP T + T PP A
Sbjct: 997 LTALRPPHPSPTATGLAALVMSPHAPSTPMTSVILGTTTTSRSSTERCPPNA 1048
Score = 49.3 bits (116), Expect = 5e-05
Identities = 85/407 (20%), Positives = 143/407 (35%), Gaps = 70/407 (17%)
Query: 1954 APALSIVEGLAEALATTTEANTSTTCVP---IAEQDCVRHI---CLEGQLIRVNQSQHCP 2007
+P+ ++G E + C P ++E CV C + + +
Sbjct: 2225 SPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWV 2284
Query: 2008 QGAAPPRCGILGLAVRVGGDRCCPLWECAC---------------RCSIFPDLSFVTFDG 2052
+C G A++ G RC C +CS++ D ++TFDG
Sbjct: 2285 SSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDG 2344
Query: 2053 SHVALFKEAIYILSQSPDEMLT-VHVLDCKSANLGHLNWPPFCLVMLN---MTHLAHQVT 2108
L Y+L ++ D + V L + N PP + L T ++V
Sbjct: 2345 FSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMD---PPRSSIFLQEVITTVYGYKVQ 2401
Query: 2109 IDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTS 2168
+ V + + P R+ G ++T ++ + + +I S S
Sbjct: 2402 LQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVI---SLPS 2458
Query: 2169 KAQG--HGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQV-------------PSS 2213
+G GLCG D + ND+ L G++ ++ F +SW+V P+
Sbjct: 2459 MYEGLVSGLCGNYDKNRKNDMMLPSGALT---QNLNTFGNSWEVKTEDALLRFPRAIPAE 2515
Query: 2214 LTSVGQTRFRPDSCATTDCSPCLRMVSNRT------------FSACHRFVPPESFCELWI 2261
G ++CSP ++ SN T F+ACH+ V PE F E +
Sbjct: 2516 EEGQGAELGLRTGLQVSECSP-EQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCV 2574
Query: 2262 RDTKYVQQP-------CVALTVYVAMCHKFHVCIE-WRRSDYCPFLC 2300
D Q P C L+ Y +C + + WR C C
Sbjct: 2575 LDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCESPC 2621
Score = 32.7 bits (73), Expect = 5.3
Identities = 25/95 (26%), Positives = 33/95 (34%), Gaps = 19/95 (20%)
Query: 707 CEASKEYSPCVAPCGRTCQDLASPE-ACGVDGGDDLSRDECVEGCACPPDTYLDTQADLC 765
C + Y C P +C+ SP +CG C EGC C P C
Sbjct: 1044 CPPNARYESCACPA--SCK---SPRPSCG---------PLCREGCVCNPGFLFSDNH--C 1087
Query: 766 VPRNQCSCHFQGVDYPPGDS--DIPSLGHCHCKDG 798
+ + C+C + Y PG HC C G
Sbjct: 1088 IQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPG 1122
>gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens]
Length = 1503
Score = 160 bits (405), Expect = 2e-38
Identities = 167/602 (27%), Positives = 229/602 (38%), Gaps = 118/602 (19%)
Query: 654 FLSPVPYFEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRA----RLPACALSCEA 709
F P E CR C+ GQ C L C+ L V R R C E
Sbjct: 850 FEGPAGSCEWCR---CQAGQVS-CVRLQCPPLPCK---LQVTERGSCCPRCRGCLAHGEE 902
Query: 710 SKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRN 769
E S V P D A +G +R +C+ CA P D C P
Sbjct: 903 HPEGSRWVPP------DSACSSCVCHEGVVTCARIQCISSCAQPRQGPHD-----CCP-- 949
Query: 770 QCS-CHFQGVDYPPGDSDIPSLGHCH---CK---DGVMS--CDSR--------------- 805
QCS C +G Y PG+S P C C+ +G S C R
Sbjct: 950 QCSDCEHEGRKYEPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQLLP 1009
Query: 806 -APAAACPA-GQVFVNCSDLHTDLELSRERTCE----QQLLNLSVSARGPCLS------- 852
P CP + NCS+ EL+ C Q L L + P LS
Sbjct: 1010 PGPQHCCPTCAEALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIHQACPELSCPLSERH 1069
Query: 853 ---GCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQ-VMSPCHTCVCQRGSFQCTLHP 908
G CP C P + C +G+E G++ + C +C C G+ +C
Sbjct: 1070 TPPGSCCP--------VCRAPTQS-CVHQGREVASGERWTVDTCTSCSCMAGTVRCQSQR 1120
Query: 909 CA-------------------------STCTAYGDRHYRTFDGLPFDFVGACKVHLVKST 943
C+ ++C A+GD HYRTFDG F G+C L K
Sbjct: 1121 CSPLSCGPDKAPALSPGSCCPRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKDC 1180
Query: 944 SDVSFSVIVENVNCYSSGMICRKFISINVGNSLIVFDDDS-----GNPSPESFLDDKQEV 998
FSV V N + SG+ + +++ +G+ + D G+P FL +
Sbjct: 1181 HSGDFSVHVTNDDRGRSGVAWTQEVAVLLGDMAVRLLQDGAVTVDGHPVALPFLQEPLLY 1240
Query: 999 HTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPEN 1058
R G ++H Q + +LWD ++ V V +QG+ GLCGNF+ ++++ PE
Sbjct: 1241 VELR-GHTVILH-AQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEG 1298
Query: 1059 LELTNPQEFGSSWAAVE---------CPDTLDPRDMCVLNPLREPFAKKECSILLSEVFE 1109
L L + FG+SW E +DP RE A C +L S F
Sbjct: 1299 LLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPCRAAGYRARRE--ANARCGVLKSSPFS 1356
Query: 1110 ICHPVVDVTWFYSNCLTDTCGCSQGGDCE-CFCASVSAYAHQCCQHGVAVDWRTPRLCPY 1168
CH VV F++ C+ D C C G + C C ++ AYA C Q GV WR P LC
Sbjct: 1357 RCHAVVPPEPFFAACVYDLCACGPGSSADACLCDALEAYASHCRQAGVTPTWRGPTLCVV 1416
Query: 1169 DC 1170
C
Sbjct: 1417 GC 1418
Score = 159 bits (403), Expect = 3e-38
Identities = 141/474 (29%), Positives = 188/474 (39%), Gaps = 74/474 (15%)
Query: 360 CCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKED 419
C +C P SC SE G CP C AP + C G G D
Sbjct: 1053 CIHQAC-PELSCPLSERHTPPGSCCPV--------CRAPTQS-CVHQGREVASGERWTVD 1102
Query: 420 -CNTCTCTSGKWECSTAVC-------------------------PAECSVTGDIHFTTFD 453
C +C+C +G C + C PA C GD H+ TFD
Sbjct: 1103 TCTSCSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPASCMAFGDPHYRTFD 1162
Query: 454 GRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQ 513
GR F +C Y+LAK SG F+V + N G A Q V+V+L V L Q
Sbjct: 1163 GRLLHFQGSCSYVLAKDCHSGDFSVHVTNDDRG-RSGVAWTQEVAVLLGD---MAVRLLQ 1218
Query: 514 AGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVE 573
G V + D + + P+ + L + + G++VL+D + ++ + V +
Sbjct: 1219 DGAVTV-DGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWDGQS-QVEVSVPGSYQG 1276
Query: 574 DTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKT---LSACSPLVSGSPLDPCDVHL 630
T GLCG FNG QDD P G+ + FGNSW+ L P +G +DPC
Sbjct: 1277 RTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPC---- 1332
Query: 631 QAASYSVQ-----ACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCG-----QPCLCATL 680
+AA Y + C VL F+ C A + P P+F C D C CG CLC L
Sbjct: 1333 RAAGYRARREANARCGVLKSSPFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDAL 1392
Query: 681 AHYAHLCRRHGLPVDFRARLPACALSC--EASKEYSPCVAPCGRTCQDLASPEACGVDGG 738
YA CR+ G+ +R C + C E + C PC RTC + P
Sbjct: 1393 EAYASHCRQAGVTPTWRGP-TLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLG------ 1445
Query: 739 DDLSRD---ECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPS 789
+L+ CV GC CP L C+P C D P G PS
Sbjct: 1446 -ELAAHCVRPCVPGCQCPAG--LVEHEAHCIPPEACPQVLLTGDQPLGARPSPS 1496
Score = 158 bits (400), Expect = 6e-38
Identities = 114/344 (33%), Positives = 152/344 (44%), Gaps = 26/344 (7%)
Query: 75 RDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCS 134
R + C A+G H TFDG + G SY L + FS+ V ND + G S +
Sbjct: 1146 RPASCMAFGDPHYRTFDGRLLHFQGSCSYVLA--KDCHSGDFSVHVTNDDR-GRSGVAWT 1202
Query: 135 RAVSLFFVGEQEIHLAKE--VTHGGMRVQLPHVMGSARLQQLAGYVIVRH-QSAFTLAWD 191
+ V++ +G+ + L ++ VT G V LP + +L G+ ++ H Q + WD
Sbjct: 1203 QEVAVL-LGDMAVRLLQDGAVTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWD 1261
Query: 192 GASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPG 251
G S V + + G T GLCGN N +DDL G L F +SWQ P
Sbjct: 1262 GQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGR 1321
Query: 252 PTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQ---- 307
P ++ PC + +C L PF CHA V P PF A+C DLC
Sbjct: 1322 PCSAGREVDPCRAAGYRARREANARCGVLKSSPFSRCHAVVPPEPFFAACVYDLCACGPG 1381
Query: 308 SMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCK-EKAFTYNECIACCPASCH 366
S D A C AL YA C QAG WR C V C E+ F ++EC CP +C
Sbjct: 1382 SSAD-ACLCDALEAYASHCRQAG-VTPTWRGP-TLCVVGCPLERGFVFDECGPPCPRTCF 1438
Query: 367 PR--------ASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECP 402
+ A CV CV GC CP GL+ + C+ P CP
Sbjct: 1439 NQHIPLGELAAHCVR---PCVPGCQCPAGLVEHEAHCIPPEACP 1479
Score = 84.3 bits (207), Expect = 2e-15
Identities = 113/404 (27%), Positives = 156/404 (38%), Gaps = 58/404 (14%)
Query: 1987 CVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACR---CSIFP 2043
C C+ G +R QSQ C +P CG A + CCP C R C F
Sbjct: 1104 CTSCSCMAGT-VRC-QSQRC----SPLSCGP-DKAPALSPGSCCP--RCLPRPASCMAFG 1154
Query: 2044 DLSFVTFDGSHVALFKEAIYILSQSPDEM-LTVHVLDCKSANLGHLNWPPFCLVMLNMTH 2102
D + TFDG + Y+L++ +VHV + G + W V+L
Sbjct: 1155 DPHYRTFDGRLLHFQGSCSYVLAKDCHSGDFSVHVTNDDRGRSG-VAWTQEVAVLLG--D 1211
Query: 2103 LAHQVTIDRFNRKVTVDLQPVWPPVSRYGFR-IEDTGHMYMILTPSDIQIQWLHSSGLMI 2161
+A ++ D VTVD PV P + +E GH ++ +Q+ W G
Sbjct: 1212 MAVRLLQDG---AVTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLW---DGQSQ 1265
Query: 2162 VEASKTSKAQGH--GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSL----- 2214
VE S QG GLCG +G A +DL +G ++ A F +SWQV L
Sbjct: 1266 VEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLL---PSEAAFGNSWQVSEGLWPGRP 1322
Query: 2215 TSVGQTRFRPDSC------ATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRD----- 2263
S G+ D C A + + ++ + FS CH VPPE F + D
Sbjct: 1323 CSAGR---EVDPCRAAGYRARREANARCGVLKSSPFSRCHAVVPPEPFFAACVYDLCACG 1379
Query: 2264 --TKYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSDS--TYQACVTACEPPKTC 2319
+ C AL Y + C + V WR C C + + C C P+TC
Sbjct: 1380 PGSSADACLCDALEAYASHCRQAGVTPTWRGPTLCVVGCPLERGFVFDECGPPC--PRTC 1437
Query: 2320 --QDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKC 2361
Q LG L + GC C G + H H CIP C
Sbjct: 1438 FNQHIPLGELAAHCVRPCVPGCQCPAGLVEHEAH---CIPPEAC 1478
Score = 58.5 bits (140), Expect = 9e-08
Identities = 66/231 (28%), Positives = 80/231 (34%), Gaps = 47/231 (20%)
Query: 720 CGRTCQDLASPEACGVDGG------DDLSRDECVEGCA------CPPDTYLDTQADLCVP 767
C C D E VDG D C EG A CP C P
Sbjct: 477 CCPRCPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPLPGTCCP 536
Query: 768 RNQCSCHFQGVDYPPGDSDIPSLGH----CHCKDGVMSCDSRA------------PAAAC 811
+ C F G +YP G +D P C C G + C +R P C
Sbjct: 537 NDCSGCAFGGKEYPSG-ADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECC 595
Query: 812 PAGQVFVNCSD------LHTDLELSRERTCEQQL-LNLSVSA-RGPCLSG-CACPQGLLR 862
P C H + C + L L+ SVS R PC CA P R
Sbjct: 596 PQCPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHP----R 651
Query: 863 HGDACFLPEECPCTWKGKEYFPGDQVMSP---CHTCVCQRGSFQCTLHPCA 910
G C P C ++GKE+ G++ SP CH C+C GS C CA
Sbjct: 652 QGPCC--PSCDGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACA 700
Score = 55.8 bits (133), Expect = 6e-07
Identities = 61/242 (25%), Positives = 84/242 (34%), Gaps = 55/242 (22%)
Query: 715 PCVAPC---GRTCQDLASPEACGVDG-------------GDDLSRDECVEGCA------C 752
PC P G C +P C G GD R C++G C
Sbjct: 583 PCPEPVLLPGECCPQCPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPC 642
Query: 753 PPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCH---CKDGVMSCDSRAPAA 809
PP + C P C +QG ++ G+ CH C +G +SC+ +A A
Sbjct: 643 PPAPCAHPRQGPCCPSCD-GCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAP 701
Query: 810 A----------CP-------AGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLS 852
A CP G+ +++ + E TC L R PC
Sbjct: 702 ALCPFPARGDCCPDCDGCEYLGESYLSNQEFPDPREPCNLCTC---LGGFVTCGRRPCEP 758
Query: 853 -GCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSP----CHTCVCQRGSFQCTLH 907
GC+ P L+ G C P C + G G+ + P C C CQ GS +C
Sbjct: 759 PGCSHP--LIPSGHCC--PTCQGCRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKK 814
Query: 908 PC 909
PC
Sbjct: 815 PC 816
Score = 50.8 bits (120), Expect = 2e-05
Identities = 53/182 (29%), Positives = 67/182 (36%), Gaps = 39/182 (21%)
Query: 707 CEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCV 766
C A +E PC A R ++ + CGV SR V PP+ + CV
Sbjct: 1323 CSAGREVDPCRAAGYRARREANA--RCGVLKSSPFSRCHAV----VPPEPFFAA----CV 1372
Query: 767 PRNQCSCHFQGVDYPPGDS------DIPSLGHCHCKDGVMSCDSRAPA---AACPA--GQ 815
+ C+C PG S D HC+ ++ R P CP G
Sbjct: 1373 -YDLCACG-------PGSSADACLCDALEAYASHCRQAGVTPTWRGPTLCVVGCPLERGF 1424
Query: 816 VFVNCSDLHTDLELSRERTCEQQ---LLNLSVSARGPCLSGCACPQGLLRHGDACFLPEE 872
VF C RTC Q L L+ PC+ GC CP GL+ H C PE
Sbjct: 1425 VFDECGP-------PCPRTCFNQHIPLGELAAHCVRPCVPGCQCPAGLVEHEAHCIPPEA 1477
Query: 873 CP 874
CP
Sbjct: 1478 CP 1479
Score = 50.4 bits (119), Expect = 2e-05
Identities = 83/312 (26%), Positives = 106/312 (33%), Gaps = 72/312 (23%)
Query: 619 SGSPL---DPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQPC 675
SG P+ DPC H + A+ SVQ C L PC PVP CR GQ C
Sbjct: 261 SGEPVGSGDPCS-HCRCANGSVQ-CEPL------PCP----PVP----CRHPGKIPGQCC 304
Query: 676 -LCATLAHYAHLCRRHGLPVDFRARLPACALSC-----EASKEYSPC-VAPCGRTCQDLA 728
+C + H ++ FR + + C E S E C V PC
Sbjct: 305 PVCDGCEYQGH---QYQSQETFRLQERGLCVRCSCQAGEVSCEEQECPVTPCALPASGRQ 361
Query: 729 SPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIP 788
AC +DG +E EG PD P C C +P
Sbjct: 362 LCPACELDG------EEFAEGVQWEPDGR---------PCTACVCQ----------DGVP 396
Query: 789 SLGHCHCKDGVMSCDSRAPAAACPA-------GQVFVNCSDLHTDLELSRERTCEQQLLN 841
G C ++ P A CP+ QV+ N + TD + S C Q
Sbjct: 397 KCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNF-TDAD-SPCHACHCQDGT 454
Query: 842 LSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMS----PCHTCVC 897
++ S + CA PQ G C CP +E F + S PC C C
Sbjct: 455 VTCSLVDCPPTTCARPQS--GPGQCC---PRCPDCILEEEVFVDGESFSHPRDPCQECRC 509
Query: 898 QRGSFQCTLHPC 909
Q G C PC
Sbjct: 510 QEGHAHCQPRPC 521
Score = 48.1 bits (113), Expect = 1e-04
Identities = 53/215 (24%), Positives = 73/215 (33%), Gaps = 45/215 (20%)
Query: 735 VDGGDDLSRDECVEGCA------CPPDTYLDTQADLCVPRNQC----SCHFQGVDYPPGD 784
V GD S C G CPP + + +P C C +QG Y +
Sbjct: 265 VGSGDPCSHCRCANGSVQCEPLPCPP---VPCRHPGKIPGQCCPVCDGCEYQGHQYQSQE 321
Query: 785 S-DIPSLG---HCHCKDGVMSCDSRAPAAACPAGQVFVNCS--DLHTDLELSRERTCEQQ 838
+ + G C C+ G +SC+ + CP + S L EL E E
Sbjct: 322 TFRLQERGLCVRCSCQAGEVSCEEQE----CPVTPCALPASGRQLCPACELDGEEFAE-- 375
Query: 839 LLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECP---------------CTWKGKEYF 883
+ G + C C G+ + G P C CT+ + Y
Sbjct: 376 --GVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYA 433
Query: 884 PGDQVM---SPCHTCVCQRGSFQCTLHPCASTCTA 915
G SPCH C CQ G+ C+L C T A
Sbjct: 434 NGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCA 468
Score = 46.2 bits (108), Expect = 5e-04
Identities = 37/128 (28%), Positives = 49/128 (38%), Gaps = 17/128 (13%)
Query: 793 CHCKDGVMSCDSRAPAAACPA----GQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARG 848
C C+DG C +A C GQ + N D TC + L +V +G
Sbjct: 117 CVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACT----TC--RCLTGAVQCQG 170
Query: 849 PCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSP---CHTCVCQRGSFQCT 905
P S C + G+ C + C CT G + G + +P C C C G QC
Sbjct: 171 PSCSELNCLESCTPPGECCPI---C-CTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCR 226
Query: 906 LHPCASTC 913
CAS C
Sbjct: 227 QRECASLC 234
Score = 44.7 bits (104), Expect = 0.001
Identities = 92/389 (23%), Positives = 121/389 (31%), Gaps = 116/389 (29%)
Query: 2326 PLDPEHCQVLGEGCVCSEGTILHRRHS---ALCIPEAK-------CACTDSMGVPRALGE 2375
PLDP C + C C EG++ ++ ALC + C S G GE
Sbjct: 794 PLDPT-CSL----CTCQEGSMRCQKKPCPPALCPHPSPGPCFCPVCHSCLSQGREHQDGE 848
Query: 2376 TWNSSLSGCCQHQCQAPDTIVPVDLGCPS--------------PRPESCLRFGEV----A 2417
+ C +CQA + V L CP PR CL GE +
Sbjct: 849 EFEGPAGSCEWCRCQAGQ-VSCVRLQCPPLPCKLQVTERGSCCPRCRGCLAHGEEHPEGS 907
Query: 2418 LLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYS----------- 2466
+P C + CVC++ + C D CCP S
Sbjct: 908 RWVPPDSAC---SSCVCHEGVVTCARIQCISSCAQPRQGPHD-CCPQCSDCEHEGRKYEP 963
Query: 2467 -------------CECDPD-------LCEAELVPS---CRQDQILITGRLGDSCCTSYFC 2503
C C+P C PS C Q+L G CC +
Sbjct: 964 GESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQLLPPGP--QHCCPTCAE 1021
Query: 2504 ACGDCPDSIP-------------ECQEGEALTVHRNTTELCCPLYQ------CVCENFRC 2544
A +C + + +CQ+ L +H+ EL CPL + C R
Sbjct: 1022 ALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIHQACPELSCPLSERHTPPGSCCPVCRA 1081
Query: 2545 PQVQC---GLGTALVEVWSPDRCCPYKSCECDCDTIPVPRCHLWEKSQLDEEFMHSVENV 2601
P C G A E W+ D C SC C T+ RC S L
Sbjct: 1082 PTQSCVHQGREVASGERWTVDTC---TSCSCMAGTV---RCQSQRCSPLS---------- 1125
Query: 2602 CGCAKYECVK----APVCLSRELGVMQPG 2626
CG K + P CL R M G
Sbjct: 1126 CGPDKAPALSPGSCCPRCLPRPASCMAFG 1154
Score = 42.0 bits (97), Expect = 0.009
Identities = 130/604 (21%), Positives = 178/604 (29%), Gaps = 164/604 (27%)
Query: 2224 PDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAMCHK 2283
P +C DCS C + + + F P C L + VQ C+A C +
Sbjct: 531 PGTCCPNDCSGCA--FGGKEYPSGADFPHPSDPCRLCRCLSGNVQ--CLARRCVPLPCPE 586
Query: 2284 FHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTC-QDGILGPLDPEHCQVLGEGC--- 2339
P L + C C P C + G E+ G+ C
Sbjct: 587 -------------PVLLPGE-----CCPQCPAPAGCPRPGAAHARHQEYFSPPGDPCRRC 628
Query: 2340 VCSEGTILHRRHSALCIPEAKCA------CTDS------MGVPRALGETWNSSLSGCCQH 2387
+C +G++ +R L P A CA C S G A GE + S + C H
Sbjct: 629 LCLDGSVSCQR---LPCPPAPCAHPRQGPCCPSCDGCLYQGKEFASGERFPSPTAAC--H 683
Query: 2388 QCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCC--------LGTVCVCNQTLC 2439
C + G S P++C P + CC LG + NQ
Sbjct: 684 LCLCWE-------GSVSCEPKAC---APALCPFPARGDCCPDCDGCEYLGESYLSNQEF- 732
Query: 2440 EGLAPTCRPGHRLLTHFQEDSCCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCT 2499
P R L T C CE P C L+PS CC
Sbjct: 733 ----PDPREPCNLCTCLGGFVTCGRRPCE--PPGCSHPLIPS-------------GHCCP 773
Query: 2500 SYFCACGDCPDSIPECQEGEALTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVW 2559
+ C C GE L + T C L C + RC + C
Sbjct: 774 T----CQGCRYHGVTTASGETLPDPLDPT---CSLCTCQEGSMRCQKKPC---------- 816
Query: 2560 SPDRCCPYKSC-ECDCDTIPVPRCHLWEKSQLDEEFMHSVENVCG-------------CA 2605
P CP+ S C C P CH + + E G C
Sbjct: 817 -PPALCPHPSPGPCFC-----PVCHSCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCV 870
Query: 2606 KYECVKAPV---------CLSRELGVMQPGQTVVELSA----DGVCHTSRCTTVLDPLTN 2652
+ +C P C R G + G+ E S D C + C +
Sbjct: 871 RLQCPPLPCKLQVTERGSCCPRCRGCLAHGEEHPEGSRWVPPDSACSSCVCHEGV----- 925
Query: 2653 FYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTTSLFLPGASWIAD 2712
+ + C C Q + P D C C + + F PGA
Sbjct: 926 ---VTCARIQCISSCA--QPRQGPHDCCPQCSDCEHEGRKYE----PGESFQPGADPCEV 976
Query: 2713 CARHHCSSTPLGAVLVR-------SPISCPPLNETECAKVGGSVVPSLEGCCRTCKEDGR 2765
C C P G +R S + CPP + P + CC TC E
Sbjct: 977 CI---CEPQPEGPPSLRCHRRQCPSLVGCPPSQ---------LLPPGPQHCCPTCAEALS 1024
Query: 2766 SCKK 2769
+C +
Sbjct: 1025 NCSE 1028
Score = 42.0 bits (97), Expect = 0.009
Identities = 66/278 (23%), Positives = 89/278 (32%), Gaps = 50/278 (17%)
Query: 659 PYFEQCRRDACRCGQ------PCLCATLAH--------YAHLCRRHGLPVDFRARLPACA 704
P + CRR C G PC A AH C G R P+
Sbjct: 620 PPGDPCRRCLCLDGSVSCQRLPCPPAPCAHPRQGPCCPSCDGCLYQGKEFASGERFPSPT 679
Query: 705 LSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQA-- 762
+C + V+ + C +P C D D +GC ++YL Q
Sbjct: 680 AACHLCLCWEGSVSCEPKAC----APALCPFPARGDCCPD--CDGCEYLGESYLSNQEFP 733
Query: 763 DLCVPRNQCSCHFQGVDY------PPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQV 816
D P N C+C V PPG S P + HC C R +G+
Sbjct: 734 DPREPCNLCTCLGGFVTCGRRPCEPPGCSH-PLIPSGHCCPTCQGC--RYHGVTTASGET 790
Query: 817 FVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDA--CFLPEECP 874
+ D L TC++ + CP L H CF P
Sbjct: 791 LPDPLDPTCSL-----CTCQEGSMRCQKKP---------CPPALCPHPSPGPCFCPVCHS 836
Query: 875 CTWKGKEYFPGDQVMSP---CHTCVCQRGSFQCTLHPC 909
C +G+E+ G++ P C C CQ G C C
Sbjct: 837 CLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQC 874
Score = 39.3 bits (90), Expect = 0.056
Identities = 62/242 (25%), Positives = 85/242 (35%), Gaps = 60/242 (24%)
Query: 2214 LTSVGQTRFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVA 2273
++S Q R P C CS C R + F P CE+ I + + P +
Sbjct: 934 ISSCAQPRQGPHDCCP-QCSDCEH--EGRKYEPGESFQPGADPCEVCICEPQPEGPPSLR 990
Query: 2274 LTVYVAMCHKFHVCIEWRRSDYCPFLCSSDSTY-------QACVTACEPPKTCQDGILG- 2325
CH+ CP L + C T E C +G+LG
Sbjct: 991 -------CHRRQ----------CPSLVGCPPSQLLPPGPQHCCPTCAEALSNCSEGLLGS 1033
Query: 2326 ---PLDPEH---CQVLGEGCV---CSEGTI-LHRRHS--ALCIPEAKCACTDSMGVPR-- 2371
P DP + CQ L C+ C E + L RH+ C P + + R
Sbjct: 1034 ELAPPDPCYTCQCQDLTWLCIHQACPELSCPLSERHTPPGSCCPVCRAPTQSCVHQGREV 1093
Query: 2372 ALGETWN-------SSLSGCCQHQCQ-------APDTIVPVDLG--CPS--PRPESCLRF 2413
A GE W S ++G + Q Q PD + G CP PRP SC+ F
Sbjct: 1094 ASGERWTVDTCTSCSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPASCMAF 1153
Query: 2414 GE 2415
G+
Sbjct: 1154 GD 1155
Score = 37.7 bits (86), Expect = 0.16
Identities = 56/248 (22%), Positives = 74/248 (29%), Gaps = 81/248 (32%)
Query: 668 ACRCGQPCL-CATLAHYAHL--CRRHGLPV-DFRARLPACALSCEASKEYSPCVAPCGRT 723
AC C C AH H C ++G + P +C C P +
Sbjct: 116 ACVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLTGAVQCQGP---S 172
Query: 724 CQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPG 783
C +L E+C G EC C ++ + + P + C
Sbjct: 173 CSELNCLESCTPPG-------ECCPICCTEGGSHWEHGQEWTTPGDPCRI---------- 215
Query: 784 DSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLS 843
C C +G + C R A+ CP
Sbjct: 216 ---------CRCLEGHIQCRQRECASLCP------------------------------- 235
Query: 844 VSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMS--PCHTCVCQRGS 901
AR L G CP D CFL G+E+ G+ V S PC C C GS
Sbjct: 236 YPARP--LPGTCCPV-----CDGCFL--------NGREHRSGEPVGSGDPCSHCRCANGS 280
Query: 902 FQCTLHPC 909
QC PC
Sbjct: 281 VQCEPLPC 288
Score = 36.6 bits (83), Expect = 0.36
Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 8/74 (10%)
Query: 852 SGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSP--CHTCVCQRGSFQCTLHPC 909
+ C C G G LP C+ G+ Y G + SP C TC C G+ QC C
Sbjct: 115 TACVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNG-ETFSPDACTTCRCLTGAVQCQGPSC 173
Query: 910 A-----STCTAYGD 918
+ +CT G+
Sbjct: 174 SELNCLESCTPPGE 187
Score = 36.6 bits (83), Expect = 0.36
Identities = 28/97 (28%), Positives = 34/97 (35%), Gaps = 5/97 (5%)
Query: 350 KAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTL 409
K F E A+CH C + ++C P F G P CE+ G
Sbjct: 667 KEFASGERFPSPTAACH-LCLCWEGSVSCEPKACAPALCPFPARGDCCPDCDGCEYLGES 725
Query: 410 YPPGSVV---KEDCNTCTCTSGKWECSTAVC-PAECS 442
Y +E CN CTC G C C P CS
Sbjct: 726 YLSNQEFPDPREPCNLCTCLGGFVTCGRRPCEPPGCS 762
Score = 36.2 bits (82), Expect = 0.48
Identities = 53/202 (26%), Positives = 70/202 (34%), Gaps = 44/202 (21%)
Query: 257 LPRPPCLQQNPGTMQGVYEQCEALLRPPFDAC----HAYVSPLPFTAS----CTSDLCQS 308
LP PP ++PG + G QC P D C H Y S F C CQ+
Sbjct: 286 LPCPPVPCRHPGKIPG---QC----CPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQA 338
Query: 309 MGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPR 368
G+V+ C CA P G RQ C+ + E + P P
Sbjct: 339 -GEVS--CEEQECPVTPCAL---PASG-----RQLCPACELDGEEFAEGVQWEPDG-RPC 386
Query: 369 ASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE-----CP----CEFHGTLYPPGSVVKE- 418
+CV C DG ++ C P + CP C +H +Y G +
Sbjct: 387 TACV-----CQDGVPKCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDA 441
Query: 419 --DCNTCTCTSGKWECSTAVCP 438
C+ C C G CS CP
Sbjct: 442 DSPCHACHCQDGTVTCSLVDCP 463
Score = 35.4 bits (80), Expect = 0.81
Identities = 88/382 (23%), Positives = 121/382 (31%), Gaps = 111/382 (29%)
Query: 2309 CVTACEPPKTC------------QDGILGPLDPEHCQVLGEGCVCSEGTILHRRH--SAL 2354
C+ +C PP C + G + C++ C C EG I R+ ++L
Sbjct: 178 CLESCTPPGECCPICCTEGGSHWEHGQEWTTPGDPCRI----CRCLEGHIQCRQRECASL 233
Query: 2355 C------IPEAKCACTDSM---GVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSP 2405
C +P C D G GE S C H A ++ L CP
Sbjct: 234 CPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSG--DPCSHCRCANGSVQCEPLPCP-- 289
Query: 2406 RPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSY 2465
P C G++ CC VC+ +G + RL QE C
Sbjct: 290 -PVPCRHPGKIP------GQCCP----VCDGCEYQGHQYQSQETFRL----QERGLCVRC 334
Query: 2466 SCECDPDLCEAE---------------LVPSCRQD--------QILITGRLGDSC----- 2497
SC+ CE + L P+C D Q GR +C
Sbjct: 335 SCQAGEVSCEEQECPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTACVCQDG 394
Query: 2498 ---CTSYFCACGDC--PDSIPE--CQEGEALTVH-------RNTTELCCPLYQCVCEN-- 2541
C + C C P P C ++ T H +N T+ P + C C++
Sbjct: 395 VPKCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADSPCHACHCQDGT 454
Query: 2542 FRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVPRCHLWEKSQLD-EEFMH---- 2596
C V C T P +CCP C P C L E+ +D E F H
Sbjct: 455 VTCSLVDCPPTTCARPQSGPGQCCP----RC-------PDCILEEEVFVDGESFSHPRDP 503
Query: 2597 -----SVENVCGCAKYECVKAP 2613
E C C +AP
Sbjct: 504 CQECRCQEGHAHCQPRPCPRAP 525
Score = 33.5 bits (75), Expect = 3.1
Identities = 42/181 (23%), Positives = 61/181 (33%), Gaps = 46/181 (25%)
Query: 300 SCTSDLCQSMGDVATWC--RALAEYARACAQAGRPLQGWRT-QLRQCT--------VHCK 348
+CT+ +CQ D A C +A + R C+Q G+ T CT V C+
Sbjct: 113 ACTACVCQ---DGAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLTGAVQCQ 169
Query: 349 EKAFTYNECIA-------CCPASCHPRAS-------------------CVDSEIACVD-- 380
+ + C+ CCP C S C++ I C
Sbjct: 170 GPSCSELNCLESCTPPGECCPICCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRE 229
Query: 381 -GCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVK--EDCNTCTCTSGKWECSTAVC 437
CP G C P C +G + G V + C+ C C +G +C C
Sbjct: 230 CASLCPYPARPLPGTC-CPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPC 288
Query: 438 P 438
P
Sbjct: 289 P 289
Score = 33.5 bits (75), Expect = 3.1
Identities = 25/84 (29%), Positives = 33/84 (39%), Gaps = 12/84 (14%)
Query: 1340 YDACASPCFQTCRDPR------AASCRDVPRVEGCVPVCPTPQVLDEVTQRCVYLEDCVE 1393
+D C PC +TC + AA C V CVP C P L E C+ E C +
Sbjct: 1426 FDECGPPCPRTCFNQHIPLGELAAHC-----VRPCVPGCQCPAGLVEHEAHCIPPEACPQ 1480
Query: 1394 PAVWVPTEALGNETLPPSQGLPTP 1417
+ + LG P + TP
Sbjct: 1481 -VLLTGDQPLGARPSPSREPQETP 1503
Score = 33.1 bits (74), Expect = 4.0
Identities = 21/76 (27%), Positives = 26/76 (34%), Gaps = 19/76 (25%)
Query: 382 CYCPNGLIF------EDGGCVAPAE-----CP----CEFHGTLYPPGSVVKED----CNT 422
C C G + E GC P CP C +HG G + + C+
Sbjct: 742 CTCLGGFVTCGRRPCEPPGCSHPLIPSGHCCPTCQGCRYHGVTTASGETLPDPLDPTCSL 801
Query: 423 CTCTSGKWECSTAVCP 438
CTC G C CP
Sbjct: 802 CTCQEGSMRCQKKPCP 817
Score = 32.7 bits (73), Expect = 5.3
Identities = 40/152 (26%), Positives = 53/152 (34%), Gaps = 20/152 (13%)
Query: 301 CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 360
CT+ +CQ D C A+ C +P CT H + A N A
Sbjct: 386 CTACVCQ---DGVPKCGAVLCPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDAD 442
Query: 361 CPA-SCHPRASCVDSEIAC--VDGCYCPNGLIF--EDGGCVAPAECP-CEFHGTLYPPG- 413
P +CH C D + C VD CP + G CP C ++ G
Sbjct: 443 SPCHACH----CQDGTVTCSLVD---CPPTTCARPQSGPGQCCPRCPDCILEEEVFVDGE 495
Query: 414 --SVVKEDCNTCTCTSGKWECSTAVCP-AECS 442
S ++ C C C G C CP A C+
Sbjct: 496 SFSHPRDPCQECRCQEGHAHCQPRPCPRAPCA 527
Score = 32.7 bits (73), Expect = 5.3
Identities = 25/90 (27%), Positives = 30/90 (33%), Gaps = 17/90 (18%)
Query: 356 ECIA--CCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPG 413
+C+A C P C P + E C C P GC P PPG
Sbjct: 573 QCLARRCVPLPC-PEPVLLPGE--CCPQCPAP-------AGCPRPGAAHARHQEYFSPPG 622
Query: 414 SVVKEDCNTCTCTSGKWECSTAVC-PAECS 442
+ C C C G C C PA C+
Sbjct: 623 ----DPCRRCLCLDGSVSCQRLPCPPAPCA 648
Score = 32.0 bits (71), Expect = 9.0
Identities = 27/92 (29%), Positives = 37/92 (40%), Gaps = 17/92 (18%)
Query: 362 PASCHPRASCVDSEIACVDGCYCP----NGLIFEDGGCVAPAECP----CEFHGTLYPPG 413
PA C +++CV CP + E G C CP C HG +P G
Sbjct: 853 PAGSCEWCRCQAGQVSCVR-LQCPPLPCKLQVTERGSC-----CPRCRGCLAHGEEHPEG 906
Query: 414 SV-VKED--CNTCTCTSGKWECSTAVCPAECS 442
S V D C++C C G C+ C + C+
Sbjct: 907 SRWVPPDSACSSCVCHEGVVTCARIQCISSCA 938
>gi|239757284 PREDICTED: similar to Fc fragment of IgG binding protein
[Homo sapiens]
Length = 593
Score = 147 bits (371), Expect = 1e-34
Identities = 143/565 (25%), Positives = 215/565 (38%), Gaps = 79/565 (13%)
Query: 546 VRTNVGVRVLYDREGLRLYLQVDQ--RWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQL 603
+ T+ G+RV YD L Y++V + + GLCG +NG+ +DDF P G
Sbjct: 23 IETDFGLRVAYD---LVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANE 79
Query: 604 FGNSWKTLSACSPLVSGSPLDP----------CDVHLQAASYSVQACSVLTGEM--FAPC 651
FGNSW+ + SP + +P P C L+ + C +L+ + C
Sbjct: 80 FGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSC 139
Query: 652 SAFLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEA 709
+ P + C D C G LC+ + Y C+ G V+ C + C
Sbjct: 140 HKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPP 199
Query: 710 SKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRN 769
+ Y C C C L++P C +D C EGC C + QA CVP
Sbjct: 200 NSHYELCADTCSLGCSALSAPPQC---------QDGCAEGCQCDSGFLYNGQA--CVPIQ 248
Query: 770 QCSCHFQGVDYPPGDSDI--PSLGHCHCKDG-VMSCDSRAPAAACPAGQVFVNCSDLHTD 826
QC C+ GV Y P + + C C G V+ C +C GQV +
Sbjct: 249 QCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEH----SCKPGQVCQPSGGI--- 301
Query: 827 LELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGD--ACFLPEECPCTWKGKEYFP 884
+C ++ S++ G + G A +L +G LP P G
Sbjct: 302 ------LSCVTKVTLRSLAQTGVDVEGAA----ILYNGQPLKVLLPLLSPDPCHG----- 346
Query: 885 GDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHL----- 939
P TC Q G C L +TC +GD HY +FDG FDF G C L
Sbjct: 347 --VTCRPQETCKEQGGQGVC-LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGC 403
Query: 940 --VKSTSDVSFSVIVENVNCYSSGMICRKFISI-NVGNSLIVFDDDSG--------NPSP 988
V + F+V +N N + + + +++ +G ++ + D+ G P
Sbjct: 404 PGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALP 463
Query: 989 ESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLK 1048
S D + V + F + + +D V V + G + GLCGN D
Sbjct: 464 VSVADGRISVTQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRN 520
Query: 1049 TINEMRTPENLELTNPQEFGSSWAA 1073
N+ P + +G SW A
Sbjct: 521 PNNDQVFPNGTLAPSIPIWGGSWRA 545
Score = 129 bits (323), Expect = 5e-29
Identities = 84/285 (29%), Positives = 128/285 (44%), Gaps = 20/285 (7%)
Query: 160 VQLPHVM--GSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNA 217
++LP V+ G R Q V++ +A+D V + + GLCGN N
Sbjct: 1 MKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNG 60
Query: 218 DPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPP----CLQQN--PGTMQ 271
DPKDD +G + EF +SW+E P+ P P T P PP C+ + P ++
Sbjct: 61 DPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPT---PCPPGSEDCIPSHKCPPELE 117
Query: 272 GVYEQ---CEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARAC 326
Y++ C L P P +CH V P C DLC G+++ C + Y AC
Sbjct: 118 KKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSAC 177
Query: 327 AQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPN 386
AG ++ WRT+ C + C + Y C C C ++ + C +GC C +
Sbjct: 178 QAAGGHVEPWRTE-TFCPMECPPNSH-YELCADTCSLGCSALSAPPQCQDGCAEGCQCDS 235
Query: 387 GLIFEDGGCVAPAECPCEFHGTLY-PPGSVVKEDC-NTCTCTSGK 429
G ++ CV +C C +G Y P +V+ ++C CTC +GK
Sbjct: 236 GFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGK 280
Score = 67.0 bits (162), Expect = 3e-10
Identities = 88/345 (25%), Positives = 125/345 (36%), Gaps = 74/345 (21%)
Query: 2174 GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQ--VPSSLTSVGQTRFRP---DSCA 2228
GLCG +GD +D +GS G A + F +SW+ VP S + T P D
Sbjct: 53 GLCGNYNGDPKDDFQKPNGSQAGNANE---FGNSWEEVVPDS-PCLPPTPCPPGSEDCIP 108
Query: 2229 TTDCSPCLR----------MVSNRT--FSACHRFVPPESFCELWIRDTKY----VQQPCV 2272
+ C P L ++S+ T S+CH+ V P+ + I D + C
Sbjct: 109 SHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCS 168
Query: 2273 ALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTAC-------EPPKTCQDGIL 2324
+ YV+ C +E WR +CP C +S Y+ C C P CQDG
Sbjct: 169 NIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDG-- 226
Query: 2325 GPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGC 2384
EGC C G + + C+P +C C + GV E + L
Sbjct: 227 ----------CAEGCQCDSGFLY---NGQACVPIQQCGCYHN-GV---YYEPEQTVLIDN 269
Query: 2385 CQHQ--CQAPDTIVPVDLGC-------PSPRPESCLRFGEVALLLPTKDPCCLGTVCVCN 2435
C+ Q C A +V + C PS SC+ + L T +
Sbjct: 270 CRQQCTCHAGKVVVCQEHSCKPGQVCQPSGGILSCVTKVTLRSLAQTGVDVEGAAILYNG 329
Query: 2436 QTL-----------CEGLAPTCRPGHRLLTHFQEDSCCPSYSCEC 2469
Q L C G+ TCRP + C P+Y C
Sbjct: 330 QPLKVLLPLLSPDPCHGV--TCRPQETCKEQGGQGVCLPNYEATC 372
Score = 66.6 bits (161), Expect = 3e-10
Identities = 47/162 (29%), Positives = 70/162 (43%), Gaps = 20/162 (12%)
Query: 1026 VHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAV----------E 1075
V V + Q+ GLCGN++ ++ + P + N EFG+SW V
Sbjct: 39 VRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTP 98
Query: 1076 CP---DTLDPRDMCVLNPLREPFAKKE-CSILLSEV--FEICHPVVDVTWFYSNCLTDTC 1129
CP + P C L + + K+E C +L S CH +VD +C+ D
Sbjct: 99 CPPGSEDCIPSHKCP-PELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDL- 156
Query: 1130 GCSQGGDCECFCASVSAYAHQCCQHGVAVD-WRTPRLCPYDC 1170
C GG+ C+++ AY C G V+ WRT CP +C
Sbjct: 157 -CLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMEC 197
Score = 46.6 bits (109), Expect = 4e-04
Identities = 45/188 (23%), Positives = 78/188 (41%), Gaps = 13/188 (6%)
Query: 73 PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS-----FSIQVHNDPQCG 127
P ++ C WG H +FDG + G +Y L P + F++ N + G
Sbjct: 366 PNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNR-G 424
Query: 128 SSPYTCSRAVSLFFVGEQ-EIHLAK--EVTHGGMRVQLPHVMGSARLQ--QLAGYVIVRH 182
+ + R V++ +G IH + +V G+ LP + R+ Q A ++
Sbjct: 425 NPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVA 484
Query: 183 QSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ 242
+++D V + + G GLCGN + +P +D V +G L + + SW
Sbjct: 485 DFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSW- 543
Query: 243 EQAPNQPP 250
+AP P
Sbjct: 544 -RAPGWDP 550
>gi|37693519 BMP-binding endothelial regulator precursor protein
[Homo sapiens]
Length = 685
Score = 145 bits (367), Expect = 4e-34
Identities = 95/332 (28%), Positives = 142/332 (42%), Gaps = 10/332 (3%)
Query: 74 ERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTC 133
E+ +C +G H TFDG + G Y L F + V ND + S ++
Sbjct: 359 EKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKNDARRTRS-FSW 417
Query: 134 SRAVSLFFVGEQEIHLAKEVT--HGGMRVQLPHVMGSARLQQLAGYVI-VRHQSAFTLAW 190
+++V L +GE + L + +T G R+ LP + L GY++ V ++ ++W
Sbjct: 418 TKSVELV-LGESRVSLQQHLTVRWNGSRIALPCRAPHFHID-LDGYLLKVTTKAGLEISW 475
Query: 191 DGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPP 250
DG S V + +P L G GLCGN N +DDL+ G DV +F SW+ ++
Sbjct: 476 DGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCN 535
Query: 251 GPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMG 310
P P P Q + +C+ L F CH+ V F SC +D+C+
Sbjct: 536 RPQRK--PVPELCQGTVKVKLRAHRECQKLKSWEFQTCHSTVDYATFYRSCVTDMCECPV 593
Query: 311 DVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRAS 370
+C + Y RAC + G + W Q CK A Y+ C C +C
Sbjct: 594 HKNCYCESFLAYTRACQREGIKVH-WEPQQNCAATQCKHGA-VYDTCGPGCIKTCDNWNE 651
Query: 371 CVDSEIACVDGCYCPNGLIFEDGGCVAPAECP 402
CV GC+CP L+ G C+ P CP
Sbjct: 652 IGPCNKPCVAGCHCPANLVLHKGRCIKPVLCP 683
Score = 134 bits (338), Expect = 1e-30
Identities = 112/453 (24%), Positives = 174/453 (38%), Gaps = 64/453 (14%)
Query: 345 VHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGC-------VA 397
V+ +F Y+ C AC +C DS + C C P G GC V
Sbjct: 244 VYDNGSSFLYDNCTAC---------TCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVP 294
Query: 398 PAECP-CEFHGTLYPPGSVVKE-DCNTCTCTSGKWECSTAVC------------------ 437
P + C+F ++ G + +C C C G+ EC C
Sbjct: 295 PEDIKVCKFGNKIFQDGEMWSSINCTICACVKGRTECRNKQCIPISSCPQGKILNRKGCC 354
Query: 438 ------PAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSS--GTFTVTLQNAPCGLNQ 489
P C+V GD H+ TFDGR + F TCQY+L K SS F V ++N +
Sbjct: 355 PICTEKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKN-DARRTR 413
Query: 490 DGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTN 549
+ +SV ++L + +V+L Q V ++ +I P F I L L+V T
Sbjct: 414 SFSWTKSVELVLGES---RVSLQQHLTV-RWNGSRIALPCRAPHFHI-DLDGYLLKVTTK 468
Query: 550 VGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWK 609
G+ + +D + + + GLCG +NG+ +DD + G + F SW+
Sbjct: 469 AGLEISWDGDSF-VEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWR 527
Query: 610 TLS--ACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRD 667
S C+ + C ++ + + C L F C + + ++ C D
Sbjct: 528 VESNEFCNRPQRKPVPELCQGTVKVKLRAHRECQKLKSWEFQTCHSTVDYATFYRSCVTD 587
Query: 668 ACRC--GQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQ 725
C C + C C + Y C+R G+ V + + A C+ Y C C +TC
Sbjct: 588 MCECPVHKNCYCESFLAYTRACQREGIKVHWEPQQNCAATQCKHGAVYDTCGPGCIKTCD 647
Query: 726 DLASPEACGVDGGDDLSRDECVEGCACPPDTYL 758
+ C CV GC CP + L
Sbjct: 648 NWNEIGPC---------NKPCVAGCHCPANLVL 671
Score = 122 bits (305), Expect = 7e-27
Identities = 138/578 (23%), Positives = 205/578 (35%), Gaps = 104/578 (17%)
Query: 674 PCLCATLAHYAHLCRRHGLPVDFR------ARLPACALSCE----------ASKEYSPCV 717
PC+ + C+R PV R + AC C+ +S ++
Sbjct: 66 PCIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCKGCTYEGNTYNSSFKWQSPA 125
Query: 718 APCG-RTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQ 776
PC R CQ+ E+ GV CV C P + +C P C F+
Sbjct: 126 EPCVLRQCQEGVVTES-GV---------RCVVHCKNPLE-----HLGMCCPTCP-GCVFE 169
Query: 777 GVDYPPGDSDIPS---LGHCHCKDGVMSCDSRA-PAAACPA-------GQVFVNC----- 820
GV Y G+ P C C G C P +CP GQ C
Sbjct: 170 GVQYQEGEEFQPEGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQCCPKCLGQRK 229
Query: 821 ------------SDLHTDLELSRERTCEQ-QLLNLSVSARGPCLSGCACPQGLLRHGDAC 867
SD++ + C + +V + C C QG + C
Sbjct: 230 VFDLPFGSCLFRSDVYDNGSSFLYDNCTACTCRDSTVVCKRKCSHPGGCDQGQEGCCEEC 289
Query: 868 FL---PEECPCTWKGKEYFPGDQVMSP--CHTCVCQRGSFQCTLHPCA------------ 910
L PE+ G + F ++ S C C C +G +C C
Sbjct: 290 LLRVPPEDIKVCKFGNKIFQDGEMWSSINCTICACVKGRTECRNKQCIPISSCPQGKILN 349
Query: 911 ------------STCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVS--FSVIVENVN 956
CT +GD HY TFDG F+F G C+ L K S + F V+V+N
Sbjct: 350 RKGCCPICTEKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKNDA 409
Query: 957 CYSSGMICRKFISINVGNSLIVFDDD---SGNPSPESFLDDKQEVHTWRVGFFTLVHFPQ 1013
+ K + + +G S + N S + H G+ V +
Sbjct: 410 RRTRSFSWTKSVELVLGESRVSLQQHLTVRWNGSRIALPCRAPHFHIDLDGYLLKVT-TK 468
Query: 1014 EHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAA 1073
+ + WD + V V A P +G+L GLCGN++ +++ + + +F SW
Sbjct: 469 AGLEISWDGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRV 528
Query: 1074 VE---C--PDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDT 1128
C P ++C + A +EC L S F+ CH VD FY +C+TD
Sbjct: 529 ESNEFCNRPQRKPVPELCQGTVKVKLRAHRECQKLKSWEFQTCHSTVDYATFYRSCVTDM 588
Query: 1129 CGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLC 1166
C C + C+C S AY C + G+ V W + C
Sbjct: 589 CECPVHKN--CYCESFLAYTRACQREGIKVHWEPQQNC 624
Score = 66.6 bits (161), Expect = 3e-10
Identities = 92/406 (22%), Positives = 154/406 (37%), Gaps = 71/406 (17%)
Query: 1986 DCVRHICLEGQLIRVNQS----QHCPQGAAPPRCGILGLAVRVGGDRCCPLW-ECACRCS 2040
+C C++G+ N+ CPQG R G CCP+ E C+
Sbjct: 318 NCTICACVKGRTECRNKQCIPISSCPQGKILNRKG------------CCPICTEKPGVCT 365
Query: 2041 IFPDLSFVTFDGSHVALFKEAIYILSQ---SPDEMLTVHVLDCKSANLGHLNWPPFCLVM 2097
+F D + TFDG Y+L++ SP V V + + +W ++
Sbjct: 366 VFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKN-DARRTRSFSWTKSVELV 424
Query: 2098 LNMTHLAHQ--VTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLH 2155
L + ++ Q +T+ ++ + P F I+ G++ + T + ++I W
Sbjct: 425 LGESRVSLQQHLTVRWNGSRIAL-------PCRAPHFHIDLDGYLLKVTTKAGLEISW-D 476
Query: 2156 SSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSS-L 2214
+ V A+ K + GLCG +G +DL DG+ +D F +SW+V S+
Sbjct: 477 GDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDD---FAESWRVESNEF 533
Query: 2215 TSVGQTRFRPDSCATT---------DCSPCLRMVSNRTFSACHRFVPPESF--------C 2257
+ Q + P+ C T +C + + + F CH V +F C
Sbjct: 534 CNRPQRKPVPELCQGTVKVKLRAHREC----QKLKSWEFQTCHSTVDYATFYRSCVTDMC 589
Query: 2258 ELWIRDTKYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFL-CSSDSTYQACVTACEPP 2316
E + Y C + Y C + + + W C C + Y C C
Sbjct: 590 ECPVHKNCY----CESFLAYTRACQREGIKVHWEPQQNCAATQCKHGAVYDTCGPGC--I 643
Query: 2317 KTCQD-GILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKC 2361
KTC + +GP + + C GC C +LH+ CI C
Sbjct: 644 KTCDNWNEIGPCN-KPCVA---GCHCPANLVLHK---GRCIKPVLC 682
Score = 41.6 bits (96), Expect = 0.011
Identities = 39/154 (25%), Positives = 55/154 (35%), Gaps = 12/154 (7%)
Query: 292 VSPLPFTASCTSDLCQSMGDVATWCRALAEY-ARACAQAGRPLQGWRTQLRQCTV--HCK 348
V +PF +C + T R +R CA A + Q + CT +
Sbjct: 56 VLQIPFITDNPCIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCKGCTYEGNTY 115
Query: 349 EKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECP-CEFHG 407
+F + C +S + CV C P E G P CP C F G
Sbjct: 116 NSSFKWQSPAEPCVLRQCQEGVVTESGVRCVVHCKNP----LEHLGMCCPT-CPGCVFEG 170
Query: 408 TLYPPGSVVKED---CNTCTCTSGKWECSTAVCP 438
Y G + + C C+CT G+ +C VCP
Sbjct: 171 VQYQEGEEFQPEGSKCTKCSCTGGRTQCVREVCP 204
Score = 34.7 bits (78), Expect = 1.4
Identities = 12/26 (46%), Positives = 15/26 (57%)
Query: 849 PCLSGCACPQGLLRHGDACFLPEECP 874
PC++GC CP L+ H C P CP
Sbjct: 658 PCVAGCHCPANLVLHKGRCIKPVLCP 683
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.134 0.440
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 134,581,752
Number of Sequences: 37866
Number of extensions: 7529964
Number of successful extensions: 50229
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 141
Number of HSP's successfully gapped in prelim test: 1710
Number of HSP's that attempted gapping in prelim test: 28266
Number of HSP's gapped (non-prelim): 11886
length of query: 2852
length of database: 18,247,518
effective HSP length: 120
effective length of query: 2732
effective length of database: 13,703,598
effective search space: 37438229736
effective search space used: 37438229736
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 71 (32.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.