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Search of human proteins with 239743134
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239743134 PREDICTED: NAC alpha domain containing [Homo
sapiens]
(1562 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|226437579 NAC alpha domain containing [Homo sapiens] 3083 0.0
gi|239743134 PREDICTED: NAC alpha domain containing [Homo sapiens] 3083 0.0
gi|239754540 PREDICTED: NAC alpha domain containing [Homo sapiens] 2961 0.0
gi|239749105 PREDICTED: NAC alpha domain containing [Homo sapiens] 2959 0.0
gi|239508792 PREDICTED: NAC alpha domain containing [Homo sapiens] 2959 0.0
gi|163965366 nascent polypeptide-associated complex alpha subuni... 327 7e-89
gi|163965362 nascent polypeptide-associated complex alpha subuni... 243 8e-64
gi|5031931 nascent polypeptide-associated complex alpha subunit ... 243 8e-64
gi|163965364 nascent polypeptide-associated complex alpha subuni... 243 8e-64
gi|40548328 nascent-polypeptide-associated complex alpha polypep... 222 2e-57
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 109 2e-23
gi|91982772 mucin 17 [Homo sapiens] 102 4e-21
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 99 4e-20
gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens] 98 5e-20
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 95 6e-19
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 95 6e-19
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 95 6e-19
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 95 6e-19
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 90 1e-17
gi|167736355 mucin 4 isoform a [Homo sapiens] 89 3e-17
gi|169205253 PREDICTED: hypothetical protein [Homo sapiens] 87 1e-16
gi|150418009 transforming, acidic coiled-coil containing protein... 87 2e-16
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 86 2e-16
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 86 2e-16
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 86 2e-16
gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 85 6e-16
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 82 4e-15
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 79 3e-14
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ... 79 3e-14
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 76 3e-13
>gi|226437579 NAC alpha domain containing [Homo sapiens]
Length = 1562
Score = 3083 bits (7994), Expect = 0.0
Identities = 1562/1562 (100%), Positives = 1562/1562 (100%)
Query: 1 MPGEAARAELLLPEADRPGPRTDLSCDAAAATTILGGDRREPCALTPGPSHLALTFLPSK 60
MPGEAARAELLLPEADRPGPRTDLSCDAAAATTILGGDRREPCALTPGPSHLALTFLPSK
Sbjct: 1 MPGEAARAELLLPEADRPGPRTDLSCDAAAATTILGGDRREPCALTPGPSHLALTFLPSK 60
Query: 61 PGARPQPEGASWDAGPGGAPSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIV 120
PGARPQPEGASWDAGPGGAPSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIV
Sbjct: 61 PGARPQPEGASWDAGPGGAPSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIV 120
Query: 121 MGEETCQALLSPRAARTALRDQEGGHASPDPPPELCSQGDLSVPSPPPDPDSFFTPPSTP 180
MGEETCQALLSPRAARTALRDQEGGHASPDPPPELCSQGDLSVPSPPPDPDSFFTPPSTP
Sbjct: 121 MGEETCQALLSPRAARTALRDQEGGHASPDPPPELCSQGDLSVPSPPPDPDSFFTPPSTP 180
Query: 181 TKTTYALLPACGPHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLA 240
TKTTYALLPACGPHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLA
Sbjct: 181 TKTTYALLPACGPHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLA 240
Query: 241 PAEGLDFPSGWGLSPQGSMVDERELHPAGTPEPPSSESSLSADSSSSWGQEGHFFDLDFL 300
PAEGLDFPSGWGLSPQGSMVDERELHPAGTPEPPSSESSLSADSSSSWGQEGHFFDLDFL
Sbjct: 241 PAEGLDFPSGWGLSPQGSMVDERELHPAGTPEPPSSESSLSADSSSSWGQEGHFFDLDFL 300
Query: 301 ANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEEAVADPDPGGDLAGEGEEDSTSAS 360
ANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEEAVADPDPGGDLAGEGEEDSTSAS
Sbjct: 301 ANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEEAVADPDPGGDLAGEGEEDSTSAS 360
Query: 361 FLQSLSDLSITEGMDEAFAFRDDTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSV 420
FLQSLSDLSITEGMDEAFAFRDDTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSV
Sbjct: 361 FLQSLSDLSITEGMDEAFAFRDDTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSV 420
Query: 421 QKTEEESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQEST 480
QKTEEESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQEST
Sbjct: 421 QKTEEESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQEST 480
Query: 481 ATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQES 540
ATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQES
Sbjct: 481 ATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQES 540
Query: 541 VTAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDS 600
VTAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDS
Sbjct: 541 VTAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDS 600
Query: 601 AMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPV 660
AMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPV
Sbjct: 601 AMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPV 660
Query: 661 AAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDS 720
AAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDS
Sbjct: 661 AAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDS 720
Query: 721 AMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV 780
AMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV
Sbjct: 721 AMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV 780
Query: 781 AAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDS 840
AAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDS
Sbjct: 781 AAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDS 840
Query: 841 AMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV 900
AMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV
Sbjct: 841 AMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV 900
Query: 901 AAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEP 960
AAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEP
Sbjct: 901 AAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEP 960
Query: 961 VATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDAD 1020
VATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDAD
Sbjct: 961 VATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDAD 1020
Query: 1021 STLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQ 1080
STLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQ
Sbjct: 1021 STLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQ 1080
Query: 1081 EGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLP 1140
EGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLP
Sbjct: 1081 EGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLP 1140
Query: 1141 SAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSV 1200
SAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSV
Sbjct: 1141 SAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSV 1200
Query: 1201 LGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVE 1260
LGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVE
Sbjct: 1201 LGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVE 1260
Query: 1261 DEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLAL 1320
DEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLAL
Sbjct: 1261 DEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLAL 1320
Query: 1321 QILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELD 1380
QILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELD
Sbjct: 1321 QILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELD 1380
Query: 1381 EQDILAPQTVQCPAQAPAGGSEETIAKAKQSRSEKKARKAMSKLGLRQIQGVTRITIQKS 1440
EQDILAPQTVQCPAQAPAGGSEETIAKAKQSRSEKKARKAMSKLGLRQIQGVTRITIQKS
Sbjct: 1381 EQDILAPQTVQCPAQAPAGGSEETIAKAKQSRSEKKARKAMSKLGLRQIQGVTRITIQKS 1440
Query: 1441 KNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPR 1500
KNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPR
Sbjct: 1441 KNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPR 1500
Query: 1501 PRVRLECKEEEEEEEEEVDEAGLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMEL 1560
PRVRLECKEEEEEEEEEVDEAGLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMEL
Sbjct: 1501 PRVRLECKEEEEEEEEEVDEAGLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMEL 1560
Query: 1561 TM 1562
TM
Sbjct: 1561 TM 1562
>gi|239743134 PREDICTED: NAC alpha domain containing [Homo sapiens]
Length = 1562
Score = 3083 bits (7994), Expect = 0.0
Identities = 1562/1562 (100%), Positives = 1562/1562 (100%)
Query: 1 MPGEAARAELLLPEADRPGPRTDLSCDAAAATTILGGDRREPCALTPGPSHLALTFLPSK 60
MPGEAARAELLLPEADRPGPRTDLSCDAAAATTILGGDRREPCALTPGPSHLALTFLPSK
Sbjct: 1 MPGEAARAELLLPEADRPGPRTDLSCDAAAATTILGGDRREPCALTPGPSHLALTFLPSK 60
Query: 61 PGARPQPEGASWDAGPGGAPSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIV 120
PGARPQPEGASWDAGPGGAPSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIV
Sbjct: 61 PGARPQPEGASWDAGPGGAPSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIV 120
Query: 121 MGEETCQALLSPRAARTALRDQEGGHASPDPPPELCSQGDLSVPSPPPDPDSFFTPPSTP 180
MGEETCQALLSPRAARTALRDQEGGHASPDPPPELCSQGDLSVPSPPPDPDSFFTPPSTP
Sbjct: 121 MGEETCQALLSPRAARTALRDQEGGHASPDPPPELCSQGDLSVPSPPPDPDSFFTPPSTP 180
Query: 181 TKTTYALLPACGPHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLA 240
TKTTYALLPACGPHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLA
Sbjct: 181 TKTTYALLPACGPHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLA 240
Query: 241 PAEGLDFPSGWGLSPQGSMVDERELHPAGTPEPPSSESSLSADSSSSWGQEGHFFDLDFL 300
PAEGLDFPSGWGLSPQGSMVDERELHPAGTPEPPSSESSLSADSSSSWGQEGHFFDLDFL
Sbjct: 241 PAEGLDFPSGWGLSPQGSMVDERELHPAGTPEPPSSESSLSADSSSSWGQEGHFFDLDFL 300
Query: 301 ANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEEAVADPDPGGDLAGEGEEDSTSAS 360
ANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEEAVADPDPGGDLAGEGEEDSTSAS
Sbjct: 301 ANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEEAVADPDPGGDLAGEGEEDSTSAS 360
Query: 361 FLQSLSDLSITEGMDEAFAFRDDTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSV 420
FLQSLSDLSITEGMDEAFAFRDDTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSV
Sbjct: 361 FLQSLSDLSITEGMDEAFAFRDDTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSV 420
Query: 421 QKTEEESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQEST 480
QKTEEESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQEST
Sbjct: 421 QKTEEESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQEST 480
Query: 481 ATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQES 540
ATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQES
Sbjct: 481 ATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQES 540
Query: 541 VTAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDS 600
VTAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDS
Sbjct: 541 VTAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDS 600
Query: 601 AMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPV 660
AMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPV
Sbjct: 601 AMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPV 660
Query: 661 AAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDS 720
AAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDS
Sbjct: 661 AAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDS 720
Query: 721 AMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV 780
AMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV
Sbjct: 721 AMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV 780
Query: 781 AAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDS 840
AAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDS
Sbjct: 781 AAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDS 840
Query: 841 AMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV 900
AMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV
Sbjct: 841 AMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV 900
Query: 901 AAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEP 960
AAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEP
Sbjct: 901 AAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEP 960
Query: 961 VATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDAD 1020
VATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDAD
Sbjct: 961 VATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDAD 1020
Query: 1021 STLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQ 1080
STLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQ
Sbjct: 1021 STLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQ 1080
Query: 1081 EGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLP 1140
EGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLP
Sbjct: 1081 EGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLP 1140
Query: 1141 SAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSV 1200
SAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSV
Sbjct: 1141 SAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSV 1200
Query: 1201 LGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVE 1260
LGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVE
Sbjct: 1201 LGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVE 1260
Query: 1261 DEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLAL 1320
DEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLAL
Sbjct: 1261 DEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLAL 1320
Query: 1321 QILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELD 1380
QILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELD
Sbjct: 1321 QILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELD 1380
Query: 1381 EQDILAPQTVQCPAQAPAGGSEETIAKAKQSRSEKKARKAMSKLGLRQIQGVTRITIQKS 1440
EQDILAPQTVQCPAQAPAGGSEETIAKAKQSRSEKKARKAMSKLGLRQIQGVTRITIQKS
Sbjct: 1381 EQDILAPQTVQCPAQAPAGGSEETIAKAKQSRSEKKARKAMSKLGLRQIQGVTRITIQKS 1440
Query: 1441 KNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPR 1500
KNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPR
Sbjct: 1441 KNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPR 1500
Query: 1501 PRVRLECKEEEEEEEEEVDEAGLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMEL 1560
PRVRLECKEEEEEEEEEVDEAGLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMEL
Sbjct: 1501 PRVRLECKEEEEEEEEEVDEAGLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMEL 1560
Query: 1561 TM 1562
TM
Sbjct: 1561 TM 1562
>gi|239754540 PREDICTED: NAC alpha domain containing [Homo sapiens]
Length = 1522
Score = 2961 bits (7676), Expect = 0.0
Identities = 1509/1562 (96%), Positives = 1514/1562 (96%), Gaps = 40/1562 (2%)
Query: 1 MPGEAARAELLLPEADRPGPRTDLSCDAAAATTILGGDRREPCALTPGPSHLALTFLPSK 60
MPGEAARAELLLPEADRPGPRTDLSCDAAAATTILGGDRREPCALTPGPSHLALTFLPSK
Sbjct: 1 MPGEAARAELLLPEADRPGPRTDLSCDAAAATTILGGDRREPCALTPGPSHLALTFLPSK 60
Query: 61 PGARPQPEGASWDAGPGGAPSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIV 120
PGARPQPEGASWDAGPGGAPSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIV
Sbjct: 61 PGARPQPEGASWDAGPGGAPSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIV 120
Query: 121 MGEETCQALLSPRAARTALRDQEGGHASPDPPPELCSQGDLSVPSPPPDPDSFFTPPSTP 180
MGEETCQALLSPRAARTALRDQEGGHASPDPPPELCSQGDLSVPSPPPDPDSFFTPPSTP
Sbjct: 121 MGEETCQALLSPRAARTALRDQEGGHASPDPPPELCSQGDLSVPSPPPDPDSFFTPPSTP 180
Query: 181 TKTTYALLPACGPHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLA 240
TKTTYALLPACGPHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLA
Sbjct: 181 TKTTYALLPACGPHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLA 240
Query: 241 PAEGLDFPSGWGLSPQGSMVDERELHPAGTPEPPSSESSLSADSSSSWGQEGHFFDLDFL 300
PAEGLDFPSGWGLSPQGSMVDERELHPAGTPEPPSSESSLSADSSSSWGQEGHFFDLDFL
Sbjct: 241 PAEGLDFPSGWGLSPQGSMVDERELHPAGTPEPPSSESSLSADSSSSWGQEGHFFDLDFL 300
Query: 301 ANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEEAVADPDPGGDLAGEGEEDSTSAS 360
ANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEEAVADPDPGGDLAGEGEEDSTSAS
Sbjct: 301 ANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEEAVADPDPGGDLAGEGEEDSTSAS 360
Query: 361 FLQSLSDLSITEGMDEAFAFRDDTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSV 420
FLQSLSDLSITEGMDEAFAFRDDTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSV
Sbjct: 361 FLQSLSDLSITEGMDEAFAFRDDTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSV 420
Query: 421 QKTEEESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQEST 480
QKTEEESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQEST
Sbjct: 421 QKTEEESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQEST 480
Query: 481 ATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQES 540
ATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQES
Sbjct: 481 ATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQES 540
Query: 541 VTAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDS 600
VTAEKLPTPQEETSLTLCPDSPQNLKEEGGL
Sbjct: 541 VTAEKLPTPQEETSLTLCPDSPQNLKEEGGL----------------------------- 571
Query: 601 AMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPV 660
DL S KPVAAATIV +QAEE LTLPQDS MTPPLPLQDT+LSSAPKPV
Sbjct: 572 -----------DLPSGRKPVAAATIVPRQAEEDLTLPQDSAMTPPLPLQDTDLSSAPKPV 620
Query: 661 AAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDS 720
AAAT+VSQQAEEGLTLPQDS MTPPLPLQDT+LSSAPKPVAAATLVSQQAEEGLTLPQDS
Sbjct: 621 AAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDS 680
Query: 721 AMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV 780
AMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV
Sbjct: 681 AMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV 740
Query: 781 AAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDS 840
AAAT+VSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDS
Sbjct: 741 AAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDS 800
Query: 841 AMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV 900
AMTPPLPLQDTDLSSAPKPVAAAT VSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV
Sbjct: 801 AMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV 860
Query: 901 AAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEP 960
AAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEP
Sbjct: 861 AAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEP 920
Query: 961 VATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDAD 1020
VATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDAD
Sbjct: 921 VATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDAD 980
Query: 1021 STLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQ 1080
STLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQ
Sbjct: 981 STLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQ 1040
Query: 1081 EGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLP 1140
EGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLP
Sbjct: 1041 EGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLP 1100
Query: 1141 SAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSV 1200
SAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSV
Sbjct: 1101 SAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSV 1160
Query: 1201 LGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVE 1260
LGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVE
Sbjct: 1161 LGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVE 1220
Query: 1261 DEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLAL 1320
DEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLAL
Sbjct: 1221 DEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLAL 1280
Query: 1321 QILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELD 1380
QILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELD
Sbjct: 1281 QILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELD 1340
Query: 1381 EQDILAPQTVQCPAQAPAGGSEETIAKAKQSRSEKKARKAMSKLGLRQIQGVTRITIQKS 1440
EQDILAPQTVQCPAQAPAGGSEETIAKAKQSRSEKKARKAMSKLGLRQIQGVTRITIQKS
Sbjct: 1341 EQDILAPQTVQCPAQAPAGGSEETIAKAKQSRSEKKARKAMSKLGLRQIQGVTRITIQKS 1400
Query: 1441 KNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPR 1500
KNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPR
Sbjct: 1401 KNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPR 1460
Query: 1501 PRVRLECKEEEEEEEEEVDEAGLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMEL 1560
PRVRLECKEEEEEEEEEVDEAGLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMEL
Sbjct: 1461 PRVRLECKEEEEEEEEEVDEAGLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMEL 1520
Query: 1561 TM 1562
TM
Sbjct: 1521 TM 1522
>gi|239749105 PREDICTED: NAC alpha domain containing [Homo sapiens]
Length = 1522
Score = 2959 bits (7672), Expect = 0.0
Identities = 1508/1562 (96%), Positives = 1514/1562 (96%), Gaps = 40/1562 (2%)
Query: 1 MPGEAARAELLLPEADRPGPRTDLSCDAAAATTILGGDRREPCALTPGPSHLALTFLPSK 60
MPGEAARAELLLPEADRPGPRTDLSCDAAAATTILGGDRREPCALTPGPSHLALTFLPSK
Sbjct: 1 MPGEAARAELLLPEADRPGPRTDLSCDAAAATTILGGDRREPCALTPGPSHLALTFLPSK 60
Query: 61 PGARPQPEGASWDAGPGGAPSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIV 120
PGARPQPEGASWDAGPGGAPSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIV
Sbjct: 61 PGARPQPEGASWDAGPGGAPSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIV 120
Query: 121 MGEETCQALLSPRAARTALRDQEGGHASPDPPPELCSQGDLSVPSPPPDPDSFFTPPSTP 180
MGEETCQALLSPRAARTALRDQEGGHASPDPPPELCSQGDLSVPSPPPDPDSFFTPPSTP
Sbjct: 121 MGEETCQALLSPRAARTALRDQEGGHASPDPPPELCSQGDLSVPSPPPDPDSFFTPPSTP 180
Query: 181 TKTTYALLPACGPHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLA 240
TKTTYALLPACGPHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLA
Sbjct: 181 TKTTYALLPACGPHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLA 240
Query: 241 PAEGLDFPSGWGLSPQGSMVDERELHPAGTPEPPSSESSLSADSSSSWGQEGHFFDLDFL 300
PAEGLDFPSGWGLSPQGSMVDERELHPAGTPEPPSSESSLSADSSSSWGQEGHFFDLDFL
Sbjct: 241 PAEGLDFPSGWGLSPQGSMVDERELHPAGTPEPPSSESSLSADSSSSWGQEGHFFDLDFL 300
Query: 301 ANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEEAVADPDPGGDLAGEGEEDSTSAS 360
ANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEEAVADPDPGGDLAGEGEEDSTSAS
Sbjct: 301 ANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEEAVADPDPGGDLAGEGEEDSTSAS 360
Query: 361 FLQSLSDLSITEGMDEAFAFRDDTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSV 420
FLQSLSDLSITEGMDEAFAFRDDTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSV
Sbjct: 361 FLQSLSDLSITEGMDEAFAFRDDTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSV 420
Query: 421 QKTEEESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQEST 480
QKTEEESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQEST
Sbjct: 421 QKTEEESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQEST 480
Query: 481 ATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQES 540
ATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQES
Sbjct: 481 ATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQES 540
Query: 541 VTAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDS 600
VTAEKLPTPQEETSLTLCPDSPQNLKEEGGL
Sbjct: 541 VTAEKLPTPQEETSLTLCPDSPQNLKEEGGL----------------------------- 571
Query: 601 AMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPV 660
DL S KPVAAATIV +QA+E LTLPQDS MTPPLPLQDT+LSSAPKPV
Sbjct: 572 -----------DLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPV 620
Query: 661 AAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDS 720
AAAT+VSQQAEEGLTLPQDS MTPPLPLQDT+LSSAPKPVAAATLVSQQAEEGLTLPQDS
Sbjct: 621 AAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDS 680
Query: 721 AMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV 780
AMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV
Sbjct: 681 AMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV 740
Query: 781 AAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDS 840
AAAT+VSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDS
Sbjct: 741 AAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDS 800
Query: 841 AMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV 900
AMTPPLPLQDTDLSSAPKPVAAAT VSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV
Sbjct: 801 AMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV 860
Query: 901 AAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEP 960
AAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEP
Sbjct: 861 AAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEP 920
Query: 961 VATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDAD 1020
VATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDAD
Sbjct: 921 VATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDAD 980
Query: 1021 STLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQ 1080
STLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQ
Sbjct: 981 STLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQ 1040
Query: 1081 EGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLP 1140
EGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLP
Sbjct: 1041 EGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLP 1100
Query: 1141 SAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSV 1200
SAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSV
Sbjct: 1101 SAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSV 1160
Query: 1201 LGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVE 1260
LGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVE
Sbjct: 1161 LGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVE 1220
Query: 1261 DEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLAL 1320
DEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLAL
Sbjct: 1221 DEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLAL 1280
Query: 1321 QILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELD 1380
QILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELD
Sbjct: 1281 QILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELD 1340
Query: 1381 EQDILAPQTVQCPAQAPAGGSEETIAKAKQSRSEKKARKAMSKLGLRQIQGVTRITIQKS 1440
EQDILAPQTVQCPAQAPAGGSEETIAKAKQSRSEKKARKAMSKLGLRQIQGVTRITIQKS
Sbjct: 1341 EQDILAPQTVQCPAQAPAGGSEETIAKAKQSRSEKKARKAMSKLGLRQIQGVTRITIQKS 1400
Query: 1441 KNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPR 1500
KNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPR
Sbjct: 1401 KNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPR 1460
Query: 1501 PRVRLECKEEEEEEEEEVDEAGLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMEL 1560
PRVRLECKEEEEEEEEEVDEAGLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMEL
Sbjct: 1461 PRVRLECKEEEEEEEEEVDEAGLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMEL 1520
Query: 1561 TM 1562
TM
Sbjct: 1521 TM 1522
>gi|239508792 PREDICTED: NAC alpha domain containing [Homo sapiens]
Length = 1522
Score = 2959 bits (7672), Expect = 0.0
Identities = 1508/1562 (96%), Positives = 1514/1562 (96%), Gaps = 40/1562 (2%)
Query: 1 MPGEAARAELLLPEADRPGPRTDLSCDAAAATTILGGDRREPCALTPGPSHLALTFLPSK 60
MPGEAARAELLLPEADRPGPRTDLSCDAAAATTILGGDRREPCALTPGPSHLALTFLPSK
Sbjct: 1 MPGEAARAELLLPEADRPGPRTDLSCDAAAATTILGGDRREPCALTPGPSHLALTFLPSK 60
Query: 61 PGARPQPEGASWDAGPGGAPSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIV 120
PGARPQPEGASWDAGPGGAPSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIV
Sbjct: 61 PGARPQPEGASWDAGPGGAPSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIV 120
Query: 121 MGEETCQALLSPRAARTALRDQEGGHASPDPPPELCSQGDLSVPSPPPDPDSFFTPPSTP 180
MGEETCQALLSPRAARTALRDQEGGHASPDPPPELCSQGDLSVPSPPPDPDSFFTPPSTP
Sbjct: 121 MGEETCQALLSPRAARTALRDQEGGHASPDPPPELCSQGDLSVPSPPPDPDSFFTPPSTP 180
Query: 181 TKTTYALLPACGPHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLA 240
TKTTYALLPACGPHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLA
Sbjct: 181 TKTTYALLPACGPHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLA 240
Query: 241 PAEGLDFPSGWGLSPQGSMVDERELHPAGTPEPPSSESSLSADSSSSWGQEGHFFDLDFL 300
PAEGLDFPSGWGLSPQGSMVDERELHPAGTPEPPSSESSLSADSSSSWGQEGHFFDLDFL
Sbjct: 241 PAEGLDFPSGWGLSPQGSMVDERELHPAGTPEPPSSESSLSADSSSSWGQEGHFFDLDFL 300
Query: 301 ANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEEAVADPDPGGDLAGEGEEDSTSAS 360
ANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEEAVADPDPGGDLAGEGEEDSTSAS
Sbjct: 301 ANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEEAVADPDPGGDLAGEGEEDSTSAS 360
Query: 361 FLQSLSDLSITEGMDEAFAFRDDTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSV 420
FLQSLSDLSITEGMDEAFAFRDDTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSV
Sbjct: 361 FLQSLSDLSITEGMDEAFAFRDDTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSV 420
Query: 421 QKTEEESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQEST 480
QKTEEESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQEST
Sbjct: 421 QKTEEESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQEST 480
Query: 481 ATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQES 540
ATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQES
Sbjct: 481 ATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQES 540
Query: 541 VTAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDS 600
VTAEKLPTPQEETSLTLCPDSPQNLKEEGGL
Sbjct: 541 VTAEKLPTPQEETSLTLCPDSPQNLKEEGGL----------------------------- 571
Query: 601 AMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPV 660
DL S KPVAAATIV +QA+E LTLPQDS MTPPLPLQDT+LSSAPKPV
Sbjct: 572 -----------DLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPV 620
Query: 661 AAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDS 720
AAAT+VSQQAEEGLTLPQDS MTPPLPLQDT+LSSAPKPVAAATLVSQQAEEGLTLPQDS
Sbjct: 621 AAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDS 680
Query: 721 AMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV 780
AMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV
Sbjct: 681 AMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV 740
Query: 781 AAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDS 840
AAAT+VSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDS
Sbjct: 741 AAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDS 800
Query: 841 AMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV 900
AMTPPLPLQDTDLSSAPKPVAAAT VSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV
Sbjct: 801 AMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV 860
Query: 901 AAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEP 960
AAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEP
Sbjct: 861 AAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEP 920
Query: 961 VATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDAD 1020
VATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDAD
Sbjct: 921 VATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDAD 980
Query: 1021 STLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQ 1080
STLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQ
Sbjct: 981 STLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQ 1040
Query: 1081 EGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLP 1140
EGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLP
Sbjct: 1041 EGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLP 1100
Query: 1141 SAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSV 1200
SAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSV
Sbjct: 1101 SAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSV 1160
Query: 1201 LGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVE 1260
LGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVE
Sbjct: 1161 LGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVE 1220
Query: 1261 DEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLAL 1320
DEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLAL
Sbjct: 1221 DEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLAL 1280
Query: 1321 QILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELD 1380
QILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELD
Sbjct: 1281 QILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELD 1340
Query: 1381 EQDILAPQTVQCPAQAPAGGSEETIAKAKQSRSEKKARKAMSKLGLRQIQGVTRITIQKS 1440
EQDILAPQTVQCPAQAPAGGSEETIAKAKQSRSEKKARKAMSKLGLRQIQGVTRITIQKS
Sbjct: 1341 EQDILAPQTVQCPAQAPAGGSEETIAKAKQSRSEKKARKAMSKLGLRQIQGVTRITIQKS 1400
Query: 1441 KNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPR 1500
KNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPR
Sbjct: 1401 KNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPR 1460
Query: 1501 PRVRLECKEEEEEEEEEVDEAGLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMEL 1560
PRVRLECKEEEEEEEEEVDEAGLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMEL
Sbjct: 1461 PRVRLECKEEEEEEEEEVDEAGLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMEL 1520
Query: 1561 TM 1562
TM
Sbjct: 1521 TM 1522
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 327 bits (837), Expect = 7e-89
Identities = 452/1602 (28%), Positives = 597/1602 (37%), Gaps = 269/1602 (16%)
Query: 82 AWADPGEGGP---SPMLLPEGLSSQALSTEAPLPATLEPRIVMGEETCQALLSPRAARTA 138
++A P GP S ++ P + A E+ PA + P G T SP T
Sbjct: 625 SYAGPDSAGPLLKSSLITP---TVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTV 681
Query: 139 LRDQEG-----GHASPDPPPELCSQGDLSVPSPPPDPDSFFT---PPSTPTKTTYALLPA 190
+ G + P S+ PSP T P P LP
Sbjct: 682 SLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPP 741
Query: 191 CGPHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLAPAEGLDFPSG 250
G + + L +SP G S +S +L+ LA + P G
Sbjct: 742 AGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPS---PLG 798
Query: 251 WGLSPQGSMVDERELHPAGTPEPPSSESSLSADSSSSWGQEGHFFDLDFLANDPMIPAAL 310
+SPQ T PP+ + S D+ G+ +P
Sbjct: 799 VSVSPQ-------------TKRPPTKKGSAGPDTPI-----GNLSSPVSPVEASFLPENS 840
Query: 311 LPFQGSLIFQVEAVEVTPLSPEEEEEEAVADP-DPGGDLAGEGEEDSTSASFLQSLSDLS 369
L FQGS TP SP+ + P P G E + S L +
Sbjct: 841 LSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGP 900
Query: 370 ITEGMDEAFAFRDDTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSVQKTEEESGG 429
T +A A S SS A A S P T GG
Sbjct: 901 ATPAPKQAPAL----SMTSSSPKKARATPAPKGIPASPSPKGAPT---PPAATPPSPKGG 953
Query: 430 GAKGLQAQDGTVSWAVE--AAPQTSDRGAYLSQRQELISEVTEEGLALGQESTATVTPHT 487
A + WA AA S +G + + + AT +P
Sbjct: 954 PATP------SPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKG 1007
Query: 488 LQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEIL----GQESVTA 543
P + T +P+ T G + A P PS +G G + A
Sbjct: 1008 APTPPAV-----TPPSPKGSPAATPFPKGASTPPAATP-PSPKGSPAATPLPKGAPTTPA 1061
Query: 544 EKLPTPQ---EETSLTLCPDSPQNL--KEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQ 598
LP+P+ SL P P +GG PS + P K L P
Sbjct: 1062 ATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPP 1121
Query: 599 DS------AMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTE 652
A TPP P + P P A T + P+ + TPP T
Sbjct: 1122 HKGAPTTPAATPPSPKGGL---ATPPPKGAPTTPAATPPS----PKGGLATPPPKGAPTT 1174
Query: 653 LSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQ---Q 709
++ P P L + + T P A TPP P + P P A T +
Sbjct: 1175 PAATP-PSPKGGLATPSPKGAPTTP---AATPPSPKGGL---ATPSPKGAPTTPAATPPS 1227
Query: 710 AEEGLTLPQDS------AMTPPLPLQDTDL---SSAPKPVAAATLVSQQAEEGLTLP--- 757
+ GL P A TPP P AP P AA + GL P
Sbjct: 1228 PKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATP---PSLKGGLATPPHK 1284
Query: 758 ---QDSAMTPPLPLQDTDLS---SAPKPVAAATIVSQQAEEGLTLPQDS----AMTPPLP 807
+ +TPP P S AP P AAT S + G P+ + A+TPP P
Sbjct: 1285 GAPNPAVVTPPSPKGGPATSPPKGAPTP-PAATPPSPKGSPGTPPPKGAPTPPAVTPPSP 1343
Query: 808 LQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDS-------AMTPPLPLQDTDLSS----- 855
+ T A P + + ++EG T P + AMTPP P + + S
Sbjct: 1344 -KGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDP 1402
Query: 856 --------APKPVAAATPVSQQAEEGLTLPQDSAMTPP----LPLQDTDLSSAPKPVAAA 903
+PK A ATPV++ EG P +TPP + L+ +SAPK
Sbjct: 1403 TSPAVIPLSPKK-APATPVTR---EGAATPSKGDLTPPAVTPVSLKKAPATSAPK----G 1454
Query: 904 TPVSQQAEEGLTLPQDSAMTAPLPLQDTGP----TSGPEPLAVATPQTLQAEAGCAPGTE 959
P + ++ TLP A+T P P + P TS A ATP + A P
Sbjct: 1455 GPATPSSKGDPTLP---AVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGA-----PTLP 1506
Query: 960 PVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDA 1019
V + +EV R P A L + PA L + P PA +P
Sbjct: 1507 AVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIP-PAMTVPSP------- 1558
Query: 1020 DSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQ 1079
+ ++P P EA + P + A T K KE L
Sbjct: 1559 -----KKTPAIPTPK--------EAPATPSSKEASSPPAVTPSTYKGAPSPKELL----- 1600
Query: 1080 QEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTL 1139
+ P P+ A PPA P + +PA + G T P
Sbjct: 1601 ----IPPAVTSPSPKEA--------PTPPAVTPPSPEKGPATPAPK-----GTPTSPPVT 1643
Query: 1140 PSAVATEASLDSCPESSVGA-VSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVP 1198
PS++ + + +GA V +G P PT+ +++ P
Sbjct: 1644 PSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTA---------------LKEVLVAP 1688
Query: 1199 SVLGTPLLQPPENLA-KGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQED 1257
+ TP++ P + + S+ P+ PDPSA G PL AP Q+D
Sbjct: 1689 APESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKG----PLSTVAPAPLLPVQKD 1744
Query: 1258 SVE-------DEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSP-- 1308
S + P G L PP P AA P VS +P P+ P
Sbjct: 1745 SSKTAKGKDASHSPKGPLA-PPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLA 1803
Query: 1309 --KVASMDAKDLALQILPPCQVPPPSGPQSPAG--------------------------P 1340
V ++ K L P + PS P +PA P
Sbjct: 1804 PSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMP 1863
Query: 1341 QGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELDEQDILAPQTVQCPAQAPAGG 1400
SA + + + GSG SDS ES EL+EQD T Q A A
Sbjct: 1864 TPKSAGIPVPTPSAKQPVTKNNKGSGTESDSD-ESVPELEEQDSTQATTQQAQLAAAAEI 1922
Query: 1401 SEETIAKAKQSRSEKKARKAMSKLGLRQIQGVTRITIQKSKNILFVIAKPDVFKSPASDT 1460
EE ++KAKQSRSEKKARKAMSKLGLRQ+ GVTR+TI+KSKNILFVI KPDV+KSPASDT
Sbjct: 1923 DEEPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDT 1982
Query: 1461 YVVFGEAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPRPRVRLECKEEEEEEEEEVDE 1520
Y+VFGEAKIEDLSQQ AAAEKFKV E + + E+ P V +EE EEEEVDE
Sbjct: 1983 YIVFGEAKIEDLSQQAQLAAAEKFKVQGEAVSNIQENTQTPTV------QEESEEEEVDE 2036
Query: 1521 AGLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMELTM 1562
G+E++DIELVM+QANVSRAKAVRAL++N +DIVNAIMELTM
Sbjct: 2037 TGVEVKDIELVMSQANVSRAKAVRALKNNSNDIVNAIMELTM 2078
Score = 103 bits (257), Expect = 1e-21
Identities = 241/1020 (23%), Positives = 348/1020 (34%), Gaps = 196/1020 (19%)
Query: 474 ALGQESTATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAM-PQPSQEGI 532
++G P T+ AP EVAT V+P + AA+ M P +E
Sbjct: 435 SVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPS 494
Query: 533 SEILGQESV-TAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQA- 590
+++ + + LP P++ +L S +K DL + + A P QA
Sbjct: 495 TQVATTLRIPVSPPLPDPEDLKNL----PSSVLVKFPTQKDLQTVPASLEGAPFSPAQAG 550
Query: 591 ----KEDLTLPQDSAMTPPLPLQDTDLSSAPKPVA-AATIVSQQAEEGLTLPQD-SVMTP 644
K+ LP A P + SS P++ AT+ + E L + + S MT
Sbjct: 551 LTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTS 610
Query: 645 PLPLQD------TELSSAPK---PVAAATLVS--------QQAEEGLTLP-----QDSAM 682
PL + T+ + P P+ ++L++ + A+ P +
Sbjct: 611 PLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYT 670
Query: 683 TPPLPLQDTDLSSAPK--PVAAATLVS----QQAEEGLTL---PQDS-AMTPPLPLQDTD 732
T P + +S APK PV TL + A E + PQ++ A L L
Sbjct: 671 TTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEI 730
Query: 733 LSSAPKP--VAAATLVSQQAEEGLTLPQDSAMTP------PLPLQD-------------T 771
S P P A T + +G++ SA+ P P +D T
Sbjct: 731 PKSVPSPSLPPAGTPPGTKKVDGIS--HTSALAPVASSPKECPTEDSGASATASSKGTLT 788
Query: 772 DLSSAPKPVAAATI------VSQQAEEGLTLPQDSAMTPPLPLQDTDLSS---------- 815
L+ +P P+ + +++ G P + +P P++ + L
Sbjct: 789 YLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKD 848
Query: 816 -----------APKPVAAATIVSQQAEEGLTLPQDSAMTP--------------PLPLQD 850
+PK + V+ + +G+TLP TP P P Q
Sbjct: 849 SPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQA 908
Query: 851 TDL---SSAPKPVAAATPVSQ---QAEEGLTLPQDSAMTPPLPLQDTDLSS---APKPVA 901
L SS+PK A ATP + + P A TPP P S AP P
Sbjct: 909 PALSMTSSSPKK-ARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTP-P 966
Query: 902 AATPVSQQAEEGLTLPQDS----AMTAPLPL---QDTGPTSGPEPLAVATPQTLQAEAGC 954
AATP S + P+ + A T P P P P P AV P + A
Sbjct: 967 AATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAAT 1026
Query: 955 ----APGTEPVATMAQQEVGEALGPRP--APEEKNAALPTVPEPAALDQVQQDDPQPAAE 1008
T P AT + A P P AP A LP+ A ++ PAA
Sbjct: 1027 PFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAAT 1086
Query: 1009 AGTPWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTG----DGA 1064
+P P S G + A + P + L H G A
Sbjct: 1087 PPSPKGG---------------PATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAA 1131
Query: 1065 KPDSPQKETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAR 1124
P SP K L + P A P+ L PP P A SP
Sbjct: 1132 TPPSP-KGGLATPPPKGAPTTPAATPPSPKGGLA------TPPPKGAPTTPAATPPSPK- 1183
Query: 1125 EERGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEP 1184
G +TP P A T A+ P+ G + +G P PA T P P
Sbjct: 1184 -----GGLATPSP--KGAPTTPAATPPSPKG--GLATPSPKGAPTTPAAT------PPSP 1228
Query: 1185 VLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDR--PLGPDPSAPGTLAGAALPP 1242
GL + P P+ TP PP KG P+TP + P P + P G A PP
Sbjct: 1229 KGGL-ATPSPKGAPT---TPAATPPS--PKGGPATPPPKGAPTPPAATPPSLKGGLATPP 1282
Query: 1243 LE-PPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSP 1301
+ P P + P PP G P P A P+ GT P G +++P
Sbjct: 1283 HKGAPNPAVVTPPSPKGGPATSPP--KGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTP 1340
Query: 1302 HSPLLSPKVASMDAKDLALQILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSPR 1361
SP +P L P P+ P S GP +A + ++ SP+
Sbjct: 1341 PSPKGTP----------TLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPK 1390
Score = 99.0 bits (245), Expect = 3e-20
Identities = 207/892 (23%), Positives = 311/892 (34%), Gaps = 154/892 (17%)
Query: 529 QEGISEILGQESVTAEKLPTPQ-EETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVP 587
Q G++ + T + +PQ ++T+++ SPQN G L L P AA ++
Sbjct: 224 QSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQN---PGSLSLKGPVSPPAALSL-S 279
Query: 588 RQAKEDLTLPQDSA--MTPP----------LPLQDTDLSS----------APKPVAAATI 625
Q+ +T Q +A TPP PL + S A TI
Sbjct: 280 TQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTI 339
Query: 626 VSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPP 685
+ G + P + PPLP ++ + P VAA +V+ ++G + +P
Sbjct: 340 SVDHSSTGASYPSQRSVIPPLPSRNEVV---PATVAAFPVVAPSVDKGPSTISSITCSPS 396
Query: 686 -----------LPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLS 734
P L S+P LV+Q +P S T PL + +
Sbjct: 397 GSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQ-------MPVSSVGTTPLVVTN---- 445
Query: 735 SAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGL 794
P +AAA + + ++ P S P+ + + +S P + A + ++ +
Sbjct: 446 --PCTIAAAPTTTFEVATCVSPPMSSG-----PISNIEPTS-PAALVMAPVAPKEPSTQV 497
Query: 795 TLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLS 854
++PPLP DL + P V + + T+P P P Q L+
Sbjct: 498 ATTLRIPVSPPLP-DPEDLKNLPSSVLVKFPTQKDLQ---TVPASLEGAPFSPAQ-AGLT 552
Query: 855 SAPKPVAAATPVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGL 914
+ P P+ Q A + Q ++ +P +PL + + A K + P+ + A
Sbjct: 553 TKKDPTVL--PLVQAAPKNSPSFQSTSSSPEIPLSP-EATLAKKSLGEPLPIGKPA---- 605
Query: 915 TLPQDSAMTAPLPLQDT----------GPTS-GP-------EPLAVATPQTLQAEAGCAP 956
S+MT+PL + + GP S GP P A P AG AP
Sbjct: 606 -----SSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAP 660
Query: 957 ----GTEPVATMAQQ--EVGEALGPR--PAPEEKNAALPTVPEPAALDQVQQDDPQPAAE 1008
GT T A E +L P+ P E LP VP + V A
Sbjct: 661 TTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAP 720
Query: 1009 AGTPWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDS 1068
T A E S + + SLP + G + + +S HT A S
Sbjct: 721 LATLVLAPEIPKS---VPSPSLPPAGTPPGTKKVDGIS------------HTSALAPVAS 765
Query: 1069 PQKETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERG 1128
KE ++ G A G + L D+P VS P + +G
Sbjct: 766 SPKEC----PTEDSGASATASSKGTLTYLA------DSPSPLGVSVSPQTKRPPTK--KG 813
Query: 1129 LSGKSTPEPTLPSAVA-TEASLDSCPESSVGAVSSLDRGC----PDAPAPTSAPTSQQPE 1183
+G TP L S V+ EAS PE+S+ S D P P+P APT
Sbjct: 814 SAGPDTPIGNLSSPVSPVEASF--LPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVT 871
Query: 1184 PVLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDRP---LGPDPSAPGTLAGAAL 1240
P+ G P E P+ L P E P+TP + L S+P
Sbjct: 872 PLSPKGVTLPPKETPTPSVVNLPFPKEG-----PATPAPKQAPALSMTSSSPKKARATPA 926
Query: 1241 PPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQ------AGVQPAAAAVSGTTQPLGTG 1294
P P +P P + P G P P+ A P+ T P G
Sbjct: 927 PKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAP 986
Query: 1295 PRVSLSPHSPLLSPKVASMDAKDLALQILPPCQVPPPSGPQSPAGPQGLSAP 1346
+ +P SP P S + PP P P + P+G S P
Sbjct: 987 TPPAATPPSPKGGPATPSPKGAPTPPAVTPP---SPKGSPAATPFPKGASTP 1035
Score = 83.6 bits (205), Expect = 1e-15
Identities = 198/966 (20%), Positives = 328/966 (33%), Gaps = 134/966 (13%)
Query: 13 PEADRPGPRTDLSCDAAAATTILGGDRREPCALTPGPSHLALTFLPSKPGARPQPEGASW 72
P + + GP T A + + A TP P + + P + P
Sbjct: 993 PPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPL 1052
Query: 73 DAGPGGAPSAWADPGEGGPSPMLL-------------PEGLSSQALSTEAPL-PATLEPR 118
G P+A +GGP+ L P+G + AP+ PA P
Sbjct: 1053 PKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPS 1112
Query: 119 IVMGEETCQALLSPRAARTALRDQEGGHASPDPPPELCSQGDLSVP--SPPPDPDSFFTP 176
G T +P +GG A+P P +G + P +PP TP
Sbjct: 1113 PKGGLATPPHKGAPTTPAATPPSPKGGLATPPP------KGAPTTPAATPPSPKGGLATP 1166
Query: 177 PSTPTKTTYALLPACGPHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSL 236
P TT A P G A S +PP SP G T ++P+ +
Sbjct: 1167 PPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP-SPKGGLATPSPKGAPTTPAATP 1225
Query: 237 SLLAPAEGLDFPSGWGL---------SPQGSMVDERELHPAGTPEPPSSESSLSADSSSS 287
+P GL PS G SP+G P G P PP++ ++
Sbjct: 1226 P--SPKGGLATPSPKGAPTTPAATPPSPKGGPATP---PPKGAPTPPAATPPSLKGGLAT 1280
Query: 288 WGQEGHFFDLDFLANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEEAVADPDPGG- 346
+G A +P + P G + P + + + P P G
Sbjct: 1281 PPHKG--------APNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGA 1332
Query: 347 ---------DLAGEGEEDSTSASFLQSLSDLSITEGMDEAFAFRDDTSAASSDSDSASYA 397
G +T+ S + S EG A + S
Sbjct: 1333 PTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRG 1392
Query: 398 EADDERLYSGEPHAQATL-----LQDSVQKTEEESGGGAKGLQAQDGTVSWAVEAAPQTS 452
A G+P + A + + T E + +KG +++ AP TS
Sbjct: 1393 PAIPSP--KGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATS 1450
Query: 453 -DRGAYLSQRQELISEVTEEGLALGQESTATVTPHTLQVAPGLQVEVATRVTPQAGEEET 511
+G + + G + VTP + + P + +VAT +P+ T
Sbjct: 1451 APKGGPATPSSK------------GDPTLPAVTPPSPKEPPAPK-QVATSSSPKKA-PAT 1496
Query: 512 DSTAGQESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLTLCPDSPQNLKEEGGL 571
+ G + +P +E + + A ++T TL +P+ +
Sbjct: 1497 PAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATL---APKEALIPPAM 1553
Query: 572 DLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAE 631
+PS +K A T P+++ TP + +S+P V +T +
Sbjct: 1554 TVPSPKKTPAIPT------------PKEAPATP-----SSKEASSPPAVTPSTYKGAPSP 1596
Query: 632 EGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDT 691
+ L +P +T P P AP P A + E+G P P+ +
Sbjct: 1597 KELLIP--PAVTSPSP------KEAPTPPA---VTPPSPEKGPATPAPKGTPTSPPVTPS 1645
Query: 692 DLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTP----PLPLQDTDLSSAPKPVAAATLVS 747
L +P A+ T + G T+PQ S P P L++ ++ AP+ + +++
Sbjct: 1646 SLKDSPTSPASVT-----CKMGATVPQASKGLPAKKGPTALKEVLVAPAPE---STPIIT 1697
Query: 748 QQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKP---VAAATIVSQQAEEGLTLP-QDSAMT 803
+G + SA +PP+ + + + P VA A ++ Q + T +D++ +
Sbjct: 1698 APTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHS 1757
Query: 804 PPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAA 863
P PL AP A+T ++ A E + +SA P L AP PV
Sbjct: 1758 PKGPL-------APPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTL 1810
Query: 864 TPVSQQAEEGLTLPQDSAMTPPLPLQDTDLSS--APKPVAAATPVSQQAEEGLTLPQDSA 921
P Q L +S P P + +L P+P++ P Q + P+ +
Sbjct: 1811 PPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPF-QSVLVNMPTPKSAG 1869
Query: 922 MTAPLP 927
+ P P
Sbjct: 1870 IPVPTP 1875
Score = 53.5 bits (127), Expect = 2e-06
Identities = 126/537 (23%), Positives = 197/537 (36%), Gaps = 83/537 (15%)
Query: 836 LPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTPP-LPLQDTDLS 894
LPQ A T LP+ SSA AA + G TLP + P PL + +
Sbjct: 16 LPQPQAETAVLPM-----SSALSVTAAL------GQPGPTLPPPCSPAPQQCPLSAANQA 64
Query: 895 SA-PKP-VAAATPVS---QQAEEGLTLPQDSAMTAPLPLQDT-GPTSGPEPLAVATPQTL 948
S P P A+TP+ Q+ G LP +A AP L + GP P LA+A+P
Sbjct: 65 SPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIA 124
Query: 949 QAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALP----TVPEPAALDQVQQDDPQ 1004
G + P+A +A P +K++A P T P A+
Sbjct: 125 PTLKGTPSSSAPLALVAL---------APHSVQKSSAFPPNLLTSPPSVAV--------- 166
Query: 1005 PAAEAGT------PWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARA 1058
AE+G+ P A E + + + +P P G + P A
Sbjct: 167 --AESGSVITLSAPIAPSEPKTNLNKVPSEVVPNP-KGTPSPPCIVSTVPYHCVTPMASI 223
Query: 1059 HTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQAR 1118
+G + P + TL + + Q + P++ + + P +PPAA +Q+
Sbjct: 224 QSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQS- 282
Query: 1119 LLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPT 1178
L + +G +TP P P ++ + L +SS G+V L + P A + + T
Sbjct: 283 -LPVVTSSQKTAGPNTP-PDFP--ISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKT 338
Query: 1179 SQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDRPLGPDP------SAP 1232
G Q +P + + P A + VD+ GP S
Sbjct: 339 ISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDK--GPSTISSITCSPS 396
Query: 1233 GTLAGAALPPLEPPAPCLCQDPQEDS----VEDEEPPGSLGLPPPQAGVQPAAAAVSGTT 1288
G+L A L P + + + + + P S+G P P A + TT
Sbjct: 397 GSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVG-TTPLVVTNPCTIAAAPTT 455
Query: 1289 ---------QPLGTGPRVSLSPHSPL------LSPKVASMD-AKDLALQILPPCQVP 1329
P+ +GP ++ P SP ++PK S A L + + PP P
Sbjct: 456 TFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDP 512
Score = 46.2 bits (108), Expect = 2e-04
Identities = 68/283 (24%), Positives = 93/283 (32%), Gaps = 42/283 (14%)
Query: 18 PGPRTDLSCDAAAATTILGGDRREPCALTPGPSHLALTFLPSKPGARPQPEGASWDAGPG 77
P P+ + AA + GG P P + P A P P+GAS
Sbjct: 980 PSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGAS------ 1033
Query: 78 GAPSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIVMGEETCQALLSPRAART 137
P+A +G P+ LP+G + PA P G T +P
Sbjct: 1034 TPPAATPPSPKGSPAATPLPKGAPT--------TPAATLPSPKGGPATPSLKGAPTPPAA 1085
Query: 138 ALRDQEGGHASPDP-----PPELCSQGDLSVPSPPPDPDSFFTPPSTPTKTTYALLPACG 192
+GG A+P P PP +PP TPP TT A P
Sbjct: 1086 TPPSPKGGPATPSPKGAPMPP---------AATPPSPKGGLATPPHKGAPTTPAATPP-S 1135
Query: 193 PHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLAPAEGLDFPSGWG 252
P G + + P SP G T ++P+ + +P GL PS G
Sbjct: 1136 PKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPP--SPKGGLATPSPKG 1193
Query: 253 L---------SPQGSMVDERELHPAGTP--EPPSSESSLSADS 284
SP+G + TP PPS + L+ S
Sbjct: 1194 APTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPS 1236
Score = 43.5 bits (101), Expect = 0.002
Identities = 61/240 (25%), Positives = 83/240 (34%), Gaps = 42/240 (17%)
Query: 46 TPGPSH---LALTFL-PSKPGARPQPEGASWDAGPGGAPSAWADPGEGGPSPMLLPEGLS 101
TP P L++T P K A P P+G P GAP+ P PSP P S
Sbjct: 902 TPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPT---PPAATPPSPKGGPATPS 958
Query: 102 SQALSTEAPLPATLEPRIVMGEETCQALLSPRAARTALRDQEGGHASPDP-----PPELC 156
+ T PA P G T +P +GG A+P P PP +
Sbjct: 959 PKWAPTP---PAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVT 1015
Query: 157 SQGDLSVPSPPPDPDSFFTPPSTPTKTTYALLPACGPHGDARDSEAELRDELLDSPPASP 216
P+ P P TPP+ T + PA P L P +P
Sbjct: 1016 PPSPKGSPAATPFPKGASTPPAA-TPPSPKGSPAATP--------------LPKGAPTTP 1060
Query: 217 SGSYITADGDSWASSPSCSLSLLAPAEGLDFPSGWGLSPQGSMVDERELHPAGTPEPPSS 276
+ + + G ++PS + PA P G +P P G P PP++
Sbjct: 1061 AATLPSPKGG--PATPSLKGAPTPPAATPPSPKGGPATPS----------PKGAPMPPAA 1108
Score = 42.4 bits (98), Expect = 0.004
Identities = 55/207 (26%), Positives = 78/207 (37%), Gaps = 19/207 (9%)
Query: 1136 EPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPH 1195
E LP A A L S++ ++L + P P P S Q P L + P
Sbjct: 13 EQELPQPQAETAVLPM--SSALSVTAALGQPGPTLPPPCSPAPQQCP---LSAANQASPF 67
Query: 1196 EVPSVLGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQD-- 1253
PS + + L+ P Q S+ PLG P AP L PP+ P A L
Sbjct: 68 PSPSTIASTPLEVPFP----QSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMI 123
Query: 1254 -PQEDSVEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPL--LSPKV 1310
P P +L P + + +A + T P P V+++ + LS +
Sbjct: 124 APTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSP----PSVAVAESGSVITLSAPI 179
Query: 1311 ASMDAKDLALQILPPCQVPPPSGPQSP 1337
A + K L +P VP P G SP
Sbjct: 180 APSEPK-TNLNKVPSEVVPNPKGTPSP 205
>gi|163965362 nascent polypeptide-associated complex alpha subunit
isoform b [Homo sapiens]
Length = 215
Score = 243 bits (621), Expect = 8e-64
Identities = 139/219 (63%), Positives = 162/219 (73%), Gaps = 10/219 (4%)
Query: 1347 EQQEDEDSLEEDSPRA---LGSGQHSDSHGESSAELDEQDILAPQTVQCPAQAPAGGSEE 1403
E E + E++ P+ GSG SDS ES EL+EQD T Q A A EE
Sbjct: 4 EATETVPATEQELPQPQAETGSGTESDSD-ESVPELEEQDSTQATTQQAQLAAAAEIDEE 62
Query: 1404 TIAKAKQSRSEKKARKAMSKLGLRQIQGVTRITIQKSKNILFVIAKPDVFKSPASDTYVV 1463
++KAKQSRSEKKARKAMSKLGLRQ+ GVTR+TI+KSKNILFVI KPDV+KSPASDTY+V
Sbjct: 63 PVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTYIV 122
Query: 1464 FGEAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPRPRVRLECKEEEEEEEEEVDEAGL 1523
FGEAKIEDLSQQ AAAEKFKV E + + E+ P V +EE EEEEVDE G+
Sbjct: 123 FGEAKIEDLSQQAQLAAAEKFKVQGEAVSNIQENTQTPTV------QEESEEEEVDETGV 176
Query: 1524 ELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMELTM 1562
E++DIELVM+QANVSRAKAVRAL++N +DIVNAIMELTM
Sbjct: 177 EVKDIELVMSQANVSRAKAVRALKNNSNDIVNAIMELTM 215
>gi|5031931 nascent polypeptide-associated complex alpha subunit
isoform b [Homo sapiens]
Length = 215
Score = 243 bits (621), Expect = 8e-64
Identities = 139/219 (63%), Positives = 162/219 (73%), Gaps = 10/219 (4%)
Query: 1347 EQQEDEDSLEEDSPRA---LGSGQHSDSHGESSAELDEQDILAPQTVQCPAQAPAGGSEE 1403
E E + E++ P+ GSG SDS ES EL+EQD T Q A A EE
Sbjct: 4 EATETVPATEQELPQPQAETGSGTESDSD-ESVPELEEQDSTQATTQQAQLAAAAEIDEE 62
Query: 1404 TIAKAKQSRSEKKARKAMSKLGLRQIQGVTRITIQKSKNILFVIAKPDVFKSPASDTYVV 1463
++KAKQSRSEKKARKAMSKLGLRQ+ GVTR+TI+KSKNILFVI KPDV+KSPASDTY+V
Sbjct: 63 PVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTYIV 122
Query: 1464 FGEAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPRPRVRLECKEEEEEEEEEVDEAGL 1523
FGEAKIEDLSQQ AAAEKFKV E + + E+ P V +EE EEEEVDE G+
Sbjct: 123 FGEAKIEDLSQQAQLAAAEKFKVQGEAVSNIQENTQTPTV------QEESEEEEVDETGV 176
Query: 1524 ELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMELTM 1562
E++DIELVM+QANVSRAKAVRAL++N +DIVNAIMELTM
Sbjct: 177 EVKDIELVMSQANVSRAKAVRALKNNSNDIVNAIMELTM 215
>gi|163965364 nascent polypeptide-associated complex alpha subunit
isoform b [Homo sapiens]
Length = 215
Score = 243 bits (621), Expect = 8e-64
Identities = 139/219 (63%), Positives = 162/219 (73%), Gaps = 10/219 (4%)
Query: 1347 EQQEDEDSLEEDSPRA---LGSGQHSDSHGESSAELDEQDILAPQTVQCPAQAPAGGSEE 1403
E E + E++ P+ GSG SDS ES EL+EQD T Q A A EE
Sbjct: 4 EATETVPATEQELPQPQAETGSGTESDSD-ESVPELEEQDSTQATTQQAQLAAAAEIDEE 62
Query: 1404 TIAKAKQSRSEKKARKAMSKLGLRQIQGVTRITIQKSKNILFVIAKPDVFKSPASDTYVV 1463
++KAKQSRSEKKARKAMSKLGLRQ+ GVTR+TI+KSKNILFVI KPDV+KSPASDTY+V
Sbjct: 63 PVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTYIV 122
Query: 1464 FGEAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPRPRVRLECKEEEEEEEEEVDEAGL 1523
FGEAKIEDLSQQ AAAEKFKV E + + E+ P V +EE EEEEVDE G+
Sbjct: 123 FGEAKIEDLSQQAQLAAAEKFKVQGEAVSNIQENTQTPTV------QEESEEEEVDETGV 176
Query: 1524 ELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMELTM 1562
E++DIELVM+QANVSRAKAVRAL++N +DIVNAIMELTM
Sbjct: 177 EVKDIELVMSQANVSRAKAVRALKNNSNDIVNAIMELTM 215
>gi|40548328 nascent-polypeptide-associated complex alpha
polypeptide-like [Homo sapiens]
Length = 215
Score = 222 bits (566), Expect = 2e-57
Identities = 128/219 (58%), Positives = 157/219 (71%), Gaps = 10/219 (4%)
Query: 1347 EQQEDEDSLEEDSPRA---LGSGQHSDSHGESSAELDEQDILAPQTVQCPAQAPAGGSEE 1403
E E + E++ P++ GSG SDS GES ++EQD T + A A EE
Sbjct: 4 EATETVPATEQELPQSQAETGSGTASDS-GESVPGIEEQDSTQTTTQKAWLVAAAEIDEE 62
Query: 1404 TIAKAKQSRSEKKARKAMSKLGLRQIQGVTRITIQKSKNILFVIAKPDVFKSPASDTYVV 1463
+ KAKQSRSEK+ARKAMSKLGL Q+ GVTR+TI KSKNILFVI K DV+KSPASD Y+V
Sbjct: 63 PVGKAKQSRSEKRARKAMSKLGLLQVTGVTRVTIWKSKNILFVITKLDVYKSPASDAYIV 122
Query: 1464 FGEAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPRPRVRLECKEEEEEEEEEVDEAGL 1523
FGEAKI+DLSQQ AAAEKF+V E + E+ P V +EE EEEEVDE G+
Sbjct: 123 FGEAKIQDLSQQAQLAAAEKFRVQGEAVGNIQENTQTPTV------QEESEEEEVDETGV 176
Query: 1524 ELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMELTM 1562
E++D++LVM+QANVSRAKAVRAL++N +DIVNAIMELT+
Sbjct: 177 EVKDVKLVMSQANVSRAKAVRALKNNSNDIVNAIMELTV 215
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 109 bits (272), Expect = 2e-23
Identities = 210/865 (24%), Positives = 309/865 (35%), Gaps = 142/865 (16%)
Query: 597 PQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSA 656
P S +PP P P A V+ Q + P+ +T P + L
Sbjct: 367 PVCSRFSPPEP------GDTPTDEPDALYVACQGQ-----PKGGHVTSMQPKEPGPLQCE 415
Query: 657 PKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPK-----PVAAATLVSQQAE 711
KP+ A + Q E L P + M P +++ LS P+ P A+ +S E
Sbjct: 416 AKPLGKAGV---QLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPE 472
Query: 712 EGLTLPQDSAMTPPLPLQDTDLSSAPK-----PVAAATLVSQQAEEGLTLPQDSAMTPPL 766
E P A+ PL+++ LS P+ P ++ S E L+ P++S PP
Sbjct: 473 ELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEES---PPS 529
Query: 767 PLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIV 826
P +T LS P+ A+ +S EE S ++PP +L ++P P A+
Sbjct: 530 PALETPLSPPPE----ASPLSPPFEE-------SPLSPP----PEELPTSPPPEASRLSP 574
Query: 827 SQQAEEGLTLPQDSAMTPPL-------PLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQD 879
+ P++S M+PP P +++ LS P+ + P +A P+D
Sbjct: 575 PPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPP--PEASRLSPPPED 632
Query: 880 SAMTPPL-------PLQDTDLSSAP-----KPVAAATPVSQQAEEGLTLPQDSAMTAPLP 927
S M+PP P + + LS P P +P+S EE T P A P
Sbjct: 633 SPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPP 692
Query: 928 LQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPVATMAQ--QEVGEALGPR--PAPEEKN 983
+D+ PTS P + A+P + P+ + + Q + GP P PEE +
Sbjct: 693 PEDS-PTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPH 751
Query: 984 AALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSL---PEPASGAGEE 1040
+ P EP Q ++ P E A E+ + E L PE + +
Sbjct: 752 LS-PRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQT 810
Query: 1041 IAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQ-QEGGLKPLAQEHG-----PR 1094
LS E CL SPQ E + Q +E L P +E +
Sbjct: 811 EEPHLSPVPEEPCL-------------SPQPEESHLSPQSEEPCLSPRPEESHLSPELEK 857
Query: 1095 SALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPE 1154
L E P P CP + L P E P + P + P
Sbjct: 858 PPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPL 917
Query: 1155 SSVGAVSSLDRGCPDAPAPTSAP---TSQQPEPVLGLGSVEQPH--------EVP---SV 1200
S G S + P P P T+ P + LG +E P E P +
Sbjct: 918 SPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPI 977
Query: 1201 LGTPLLQPPE-NLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSV 1259
L TP+ PPE N +P P+ P +PG+ G A P L P P C + S+
Sbjct: 978 LETPISPPPEANCTDPEPVPPMILP-----PSPGSPVGPASPILMEPLPPQCSPLLQHSL 1032
Query: 1260 EDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLA 1319
+ P S PP +V P+ G V +S + L + +
Sbjct: 1033 VPQNSPPSQCSPP------ALPLSVPSPLSPI--GKVVGVSDEAELHEMETEKVSE---- 1080
Query: 1320 LQILPPCQVPPPSGPQSPAGPQG-LSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAE 1378
P C PS P G LS P +P + GE +A
Sbjct: 1081 ----PECPALEPSATSPLPSPMGDLSCP------------APSPAPALDDFSGLGEDTAP 1124
Query: 1379 LDEQDILAPQTVQCPAQAPAGGSEE 1403
LD D AP + P Q P + E
Sbjct: 1125 LDGID--APGSQPEPGQTPGSLASE 1147
Score = 70.9 bits (172), Expect = 9e-12
Identities = 221/931 (23%), Positives = 324/931 (34%), Gaps = 162/931 (17%)
Query: 503 TPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLTLCPDSP 562
+P + EE+ + E+ P+ S S E+LPT + L P
Sbjct: 518 SPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPE 577
Query: 563 QNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAA 622
++ + P P A+ P + P++S ++PP + S P
Sbjct: 578 ESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPP---PEASRLSPP----- 629
Query: 623 ATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAM 682
P+DS M+P P +++ +S P+ VS+ + LP S +
Sbjct: 630 --------------PEDSPMSP--PPEESPMSPPPE-------VSRLS----PLPVVSRL 662
Query: 683 TPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAA 742
+P P +++ LS P P + T +A P+DS +PP D ++P P +
Sbjct: 663 SP--PPEESPLS--PPPEESPTSPPPEASRLSPPPEDSPTSPP----PEDSPASPPPEDS 714
Query: 743 ATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPK-----PVAAATIVSQQAEEGLTLP 797
+ + L LP++ + P + LS P+ P +S QAEE P
Sbjct: 715 LMSLPLEESPLLPLPEEPQLCP--RSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSP 772
Query: 798 QDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAP 857
Q ++ LS P A +S Q EE PQ ++ LS
Sbjct: 773 QPEEPCLCAVPEEPHLS----PQAEGPHLSPQPEELHLSPQ---------TEEPHLS--- 816
Query: 858 KPVAAATPVSQQAEEGLTLPQ-DSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTL 916
PV +S Q EE PQ + P P +++ LS P P+S + E+
Sbjct: 817 -PVPEEPCLSPQPEESHLSPQSEEPCLSPRP-EESHLS----PELEKPPLSPRPEKPPEE 870
Query: 917 PQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPVATMAQQEVGEALGPR 976
P LPL P P + L A PG P++
Sbjct: 871 PGQCPAPEELPL-------FPPPGEPSLSPLLGEPALSEPGEPPLS-------------- 909
Query: 977 PAPEEKNAALPTVP--EPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLG-----MEALS 1029
P PEE LP P EP+ Q+ DP P + AA A S LG A
Sbjct: 910 PLPEE----LPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKG 965
Query: 1030 LPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQ 1089
+P S I E P EA P SP G P+
Sbjct: 966 DSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSP--------GSPVGPASPILM 1017
Query: 1090 EHGPR--SALGGAREVP-DAPPAACP----EVSQARLLSPAREERGLSGKSTPEPTLPSA 1142
E P S L VP ++PP+ C +S LSP + G+S E L
Sbjct: 1018 EPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVS----DEAELHEM 1073
Query: 1143 VATEASLDSCPESSVGAVSSL-----DRGCP-DAPAPTSAPTSQQPEPVLGLGSVEQPHE 1196
+ S CP A S L D CP +PAP S E L ++ P
Sbjct: 1074 ETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGS 1133
Query: 1197 VPSVLGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQE 1256
P Q P +LA +PV L P+ AP T P+E C Q
Sbjct: 1134 QPEP-----GQTPGSLASELKGSPV--LLDPEELAPVT-------PMEVYPECKQTAGQG 1179
Query: 1257 DSVEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHS-PLL-SPKVASMD 1314
E++E P + P P ++ + + L G + P S PLL SP
Sbjct: 1180 SPCEEQEEPRAPVAPTPPTLIK---SDIVNEISNLSQGDASASFPGSEPLLGSPDPEGGG 1236
Query: 1315 AKDLALQILPPCQVPPPSGPQSPAGPQG---LSAPEQQEDEDSLEEDSPRALGSGQHSDS 1371
+ + L + S SPA +G L E +DSL D+ A+ G+
Sbjct: 1237 SLSMELGV---------STDVSPARDEGSLRLCTDSLPETDDSLLCDAGTAISGGKAEGE 1287
Query: 1372 HGESSAELDEQDILAPQTVQCPA-QAPAGGS 1401
G + I ++ P + P GG+
Sbjct: 1288 KGRRRSSPARSRIKQGRSSSFPGRRRPRGGA 1318
Score = 49.3 bits (116), Expect = 3e-05
Identities = 154/683 (22%), Positives = 230/683 (33%), Gaps = 101/683 (14%)
Query: 647 PLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLV 706
P T + PKP L+ + +GL + Q S P P Q P VA V
Sbjct: 3761 PGVQTNQALGPKPQG---LMPPSSHQGLLVQQLS----PQPPQGPQGMLGPAQVA----V 3809
Query: 707 SQQAEEGLTLPQDS----AMTPPLPLQDTDLSSAPKPVAAATLVS-QQAEEGLTLPQDSA 761
QQ G PQ MT L L+ + + LV+ QQ ++ Q +
Sbjct: 3810 LQQQHPGALGPQGPHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGS 3869
Query: 762 MTPPLPLQDTDLSSAPKPVAAATIVS--QQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKP 819
M LQ + +S + +P +A + QQ ++ L Q L Q +
Sbjct: 3870 MAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQ----LQQQQQQQLQQQQQ 3925
Query: 820 VAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQD 879
+ + QQ ++ L Q L Q L + QQ ++ L Q
Sbjct: 3926 LQQQQLQQQQQQQQLQQQQQQQ----LQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQS 3981
Query: 880 SAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQ----DSAMTAPLPLQDTGPTS 935
+ P Q ++ P A P+ + G P P + T
Sbjct: 3982 RTLLSPQQQQQQQVALGPG--MPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATE 4039
Query: 936 GPE-----PLAVAT-PQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTV 989
GP PLA+ T P+++ E G E +++ + P+P P+ + L
Sbjct: 4040 GPSTHQGGPLAIGTTPESMATEPG-----EVKPSLSGDSQLLLVQPQPQPQPSSLQLQP- 4093
Query: 990 PEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLP----EPASGAGEE---IA 1042
P L QQ AG Q + S+ EA S+P +P+ G++ +
Sbjct: 4094 --PLRLPGQQQQQVSLLHTAGGGSHGQLGSGSS--SEASSVPHLLAQPSVSLGDQPGSMT 4149
Query: 1043 EALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALGGARE 1102
+ L P ++ LE G +P P + G+ P + R+ L G
Sbjct: 4150 QNLLGP-QQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQL--RAQLQGVLA 4206
Query: 1103 VPDAPPAACPEVSQA--RLLSPAREERGLSGKSTP---EP-----TLPSAVATEASLDSC 1152
P+ Q LL + ++ + + TP EP L + + L
Sbjct: 4207 KNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGF 4266
Query: 1153 PESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPENL 1212
P G + L G P P P P L G V P V TP P+
Sbjct: 4267 PGPQTGPLQELGAG----PRPQGPPRLPAPPGALSTGPVLGP-----VHPTPPPSSPQ-- 4315
Query: 1213 AKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPP 1272
+P P P P P A LPP P P PQ ++E P
Sbjct: 4316 ---EPKRPSQLP-SPSSQLP---TEAQLPPTHPGTP----KPQGPTLE-----------P 4353
Query: 1273 PQAGVQPAAAAVSGTTQPLGTGP 1295
P V PAAA ++ T G GP
Sbjct: 4354 PPGRVSPAAAQLADTLFSKGLGP 4376
Score = 45.1 bits (105), Expect = 5e-04
Identities = 78/294 (26%), Positives = 107/294 (36%), Gaps = 46/294 (15%)
Query: 45 LTPGPSHLALTFLPSKPGARPQPEGASWDAGPGGAPSAWADPGEGGPSPMLLPEGLS--- 101
L+P P L +P +P PQ EG P P E SP LS
Sbjct: 770 LSPQPEEPCLCAVPEEPHLSPQAEG----------PHLSPQPEELHLSPQTEEPHLSPVP 819
Query: 102 SQALSTEAPLPATLEPRIVMGEETCQALLSPRAARTALRDQ-EGGHASPDP--PPELCSQ 158
+ + P + L P+ EE C LSPR + L + E SP P PPE Q
Sbjct: 820 EEPCLSPQPEESHLSPQ---SEEPC---LSPRPEESHLSPELEKPPLSPRPEKPPEEPGQ 873
Query: 159 GDLSVPSPPPDPDSFFTPPSTPTKTTYALLPACGPHGDARDSEAELRDELLDSPPASPSG 218
P P+ F PP P+ + PA G+ S L +EL SP PS
Sbjct: 874 ------CPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLS--PLPEELPLSPSGEPSL 925
Query: 219 SYITADGDSWASSPSCSLSLLAPAEGLDFPSGWGLSPQGSMVDERELHPAGTPEPPSSES 278
S D S ++ AP LSP G + E G +P S +
Sbjct: 926 SPQLMPPDPLPPPLSPIITAAAPP---------ALSPLGEL--EYPFGAKGDSDPESPLA 974
Query: 279 SLSADSSSSWGQEGHFFDLDFLANDPMIPAALLPFQGSLIFQVEAVEVTPLSPE 332
+ ++ S E + D +P+ P L P GS + + + PL P+
Sbjct: 975 APILETPISPPPEANCTD-----PEPVPPMILPPSPGSPVGPASPILMEPLPPQ 1023
Score = 43.9 bits (102), Expect = 0.001
Identities = 134/609 (22%), Positives = 197/609 (32%), Gaps = 68/609 (11%)
Query: 606 LPLQDTDLSSAPKPVAAATIV--SQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAA 663
+P Q L S P P AA TI S GL+ D + PP S P P +
Sbjct: 2106 IPPQPGALGSPP-PAAAPTIFIGSPTTPAGLSTSADGFLKPPA-------GSVPGPDSPG 2157
Query: 664 TLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMT 723
L L LP + +P QD + P+ + P +
Sbjct: 2158 ELF-------LKLPPQ--VPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQ 2208
Query: 724 PPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAA 783
PP+ L ++ +P A G Q S P L + L + P +
Sbjct: 2209 PPM------LGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPG 2262
Query: 784 TIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMT 843
+ +E L+ P L ++ +L ++ + + P
Sbjct: 2263 VGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDS------PSSGTHL 2316
Query: 844 PPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTL--PQDSAMTPPLPLQDTDL-------S 894
L L+ D+ AP A+ Q GL P + P P D+
Sbjct: 2317 GGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTD 2376
Query: 895 SAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGC 954
+P P E LP S + P P S + TP+ L AEA C
Sbjct: 2377 PYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFC 2436
Query: 955 APGTEPVATMAQQEVGEALGP-RPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPW 1013
PV Q + P RP + A L P P P+ A +AG+
Sbjct: 2437 ---PSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRP--------QPPEVAFKAGSL- 2484
Query: 1014 AAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKET 1073
A ++LG PA AGE A+ S G+ TG SP + T
Sbjct: 2485 -----AHTSLGAGGFPAALPAGPAGELHAKVPS--GQPPNFVRSPGTGAFVGTPSPMRFT 2537
Query: 1074 LEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLS----PAREERGL 1129
+ E LKP + G G P P+ + + + P+ G
Sbjct: 2538 FP-QAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGP 2596
Query: 1130 SGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLG 1189
S ST E S + + L P + G++ L G TS P ++ +P G+G
Sbjct: 2597 SSGSTGESYGLSPLRPPSVLP--PPAPDGSLPYLSHGASQRSGITS-PVEKREDPGTGMG 2653
Query: 1190 SVEQPHEVP 1198
S E+P
Sbjct: 2654 SSLATAELP 2662
Score = 43.1 bits (100), Expect = 0.002
Identities = 137/635 (21%), Positives = 199/635 (31%), Gaps = 78/635 (12%)
Query: 727 PLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIV 786
P T+ + PKP L+ + +GL + Q S P P Q P VA V
Sbjct: 3761 PGVQTNQALGPKPQG---LMPPSSHQGLLVQQLS----PQPPQGPQGMLGPAQVA----V 3809
Query: 787 SQQAEEGLTLPQDS----AMTPPLPLQDTDLSSAPKPVAAATIVS-QQAEEGLTLPQDSA 841
QQ G PQ MT L L+ + + +V+ QQ ++ Q +
Sbjct: 3810 LQQQHPGALGPQGPHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGS 3869
Query: 842 MTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVA 901
M LQ + +S + +P +A P+ + L Q + LQ +
Sbjct: 3870 MAGLSHLQQSLMSHSGQPKLSAQPMGSLQQ----LQQQQQLQQQQQLQQQQQQQLQQQQQ 3925
Query: 902 AATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPV 961
QQ ++ L Q Q + Q Q +
Sbjct: 3926 LQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLL 3985
Query: 962 ATMAQQEVGEALGP-RPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDAD 1020
+ QQ+ ALGP PA ++ + P P L ++ Q D
Sbjct: 3986 SPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKE---------------QNTVD 4030
Query: 1021 STLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQ 1080
+ EA P G I G P+S E EV+
Sbjct: 4031 PAVSSEATEGPSTHQGGPLAI---------------------GTTPESMATEPGEVKPSL 4069
Query: 1081 EGGLKPLAQEHGPRSALGGAREVPDA--PPAACPEVSQARLLSPAREERGLSGKSTPEPT 1138
G + L + P+ + P P +VS + SG S+ +
Sbjct: 4070 SGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASS 4129
Query: 1139 LPSAVATEA-SLDSCPESSVGAVSSLDRGCPDAPAPTSA-PTSQQPEPVLGLGSVEQPHE 1196
+P +A + SL P S + + + P + P +P PVL G
Sbjct: 4130 VPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVG 4189
Query: 1197 VPSVLGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDP-- 1254
+ +G Q LAK P R L P L + + + Q P
Sbjct: 4190 IMPTVGQLRAQLQGVLAKN----PQLRHLSPQQQQQ--LQALLMQRQLQQSQAVRQTPPY 4243
Query: 1255 QEDSVEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMD 1314
QE + G LG P G +G Q LG GPR P P A
Sbjct: 4244 QEPGTQTSPLQGLLGCQPQLGGFP---GPQTGPLQELGAGPRPQGPPRLP------APPG 4294
Query: 1315 AKDLALQILPPCQVPPPSGPQSPAGPQGLSAPEQQ 1349
A + P PPPS PQ P P L +P Q
Sbjct: 4295 ALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQ 4329
Score = 42.4 bits (98), Expect = 0.004
Identities = 193/878 (21%), Positives = 303/878 (34%), Gaps = 152/878 (17%)
Query: 605 PLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAAT 664
P P D +S P+ + V + EEG P P Q T + +P AA
Sbjct: 3100 PPPAAD---ASEPRLASVLPEVKPKVEEGGRHPS--------PCQFTIATPKVEPAPAAN 3148
Query: 665 LVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTP 724
+ GL L +M + +DT + + P + T +++A G T + +
Sbjct: 3149 SL------GLGLKPGQSM---MGSRDTRMGTGPFSSSGHT--AEKASFGATGGPPAHLLT 3197
Query: 725 PLPLQDTDLSSAPKPVAAATLVSQQAEEG-LTLPQDSAMT-PPLPLQDTDLSSAPKPVAA 782
P PL P ++ L + E G LTLP A + L ++ L ++ P+
Sbjct: 3198 PSPLSG--------PGGSSLLEKFELESGALTLPGGPAASGDELDKMESSLVASELPLLI 3249
Query: 783 ATIVSQQAEEGLTLPQDSAMTPPLPLQDTD-----LSSAPKPVAAATIVSQQA------- 830
++ + +E Q SA P Q L SAP P A ++ + +
Sbjct: 3250 EDLLEHEKKELQKKQQLSAQLQPAQQQQQQQQQHSLLSAPGPAQAMSLPHEGSSPSLAGS 3309
Query: 831 EEGLTLPQDSAMTP--PLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLP-QDSAMTPPLP 887
++ L+L A P P PL T + A ++ + +G L Q +P
Sbjct: 3310 QQQLSLGLAGARQPGLPQPLMPTQPPAHALQQRLAPSMAMVSNQGHMLSGQHGGQAGLVP 3369
Query: 888 LQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPE---PLAVAT 944
Q + + KP+ P + L + Q A + P D + + P+A A
Sbjct: 3370 QQSSQPVLSQKPMGTMPPSMCMKPQQLAMQQQLANSF-FPDTDLDKFAAEDIIDPIAKAK 3428
Query: 945 PQTL--------QAEAGCAPGT--EPVATMAQQEVGEALGPRP---------APEEKNAA 985
L Q G APG + V+ +AQ+ G GP + +E++A
Sbjct: 3429 MVALKGIKKVMAQGSIGVAPGMNRQQVSLLAQRLSG---GPSSDLQNHVAAGSGQERSAG 3485
Query: 986 LPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPASGAGEEIAEAL 1045
P+ P P +P A+ A Q + L L E+I +
Sbjct: 3486 DPSQPRP---------NPPTFAQGVINEADQRQYEEWLFHTQQLLQMQLKVLEEQIG--V 3534
Query: 1046 SRPGREA-CLEARAHTGDGAKPDSPQKETLEVENQQEGGL-KPLAQ------EHGPRSA- 1096
R R+A C + R G + E L++ +Q+ + K L Q EH A
Sbjct: 3535 HRKSRKALCAKQRTAKKAGREFPEADAEKLKLVTEQQSKIQKQLDQVRKQQKEHTNLMAE 3594
Query: 1097 -LGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPES 1155
++ + S LSP++ R L+ LP + L P+
Sbjct: 3595 YRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRLLT-------KLPGQLLPGHGLQP-PQG 3646
Query: 1156 SVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLAKG 1215
G + R P A P P L +Q + S L P G
Sbjct: 3647 PPGGQAGGLRLTPGGMALPGQPGG----PFLNTALAQQQQQQHSGGAGSLAGPSGGFFPG 3702
Query: 1216 QPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQA 1275
+ R LGPD L L+ L Q Q+ + ++ LG Q
Sbjct: 3703 NLAL---RSLGPD----SRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLG----QV 3751
Query: 1276 GVQPAAAAVSG--TTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLALQILPPCQVPPPSG 1333
+Q G T Q LG P+ + P S + L +Q L P PP G
Sbjct: 3752 AIQQQQQQGPGVQTNQALGPKPQGLMPPSSH-----------QGLLVQQLSP---QPPQG 3797
Query: 1334 PQSPAGPQGLSAPEQQEDEDSLEEDSPRALG-SGQHSDSHGESSAELDEQDILAPQTVQC 1392
PQ GP ++ +QQ P ALG G H S L +
Sbjct: 3798 PQGMLGPAQVAVLQQQH---------PGALGPQGPHRQVLMTQSRVLSSPQL-------- 3840
Query: 1393 PAQAPAGGSEETIAKAKQSRSEKKARKAMSKLGLRQIQ 1430
AQ G + A+Q + +++ ++ S GL +Q
Sbjct: 3841 -AQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQ 3877
Score = 40.8 bits (94), Expect = 0.010
Identities = 87/375 (23%), Positives = 133/375 (35%), Gaps = 54/375 (14%)
Query: 931 TGPTSGPEPLAVATPQTLQAEA--GCAP----GTEPVATMAQQEVGEALGPRPAPEEKN- 983
+ P + P L P ++Q + G P G P + ++ AL R E K+
Sbjct: 4617 SNPPTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERAL--RDTSEVKSL 4674
Query: 984 ---AALPTVPEPAALD-QVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPASGAGE 1039
AALPT P D +++ D+ + ++ P ++ E S LG EA P SG E
Sbjct: 4675 DLLAALPTPPHNQTEDVRMESDEDSDSPDSIVPASSPE---SILGEEAPRFPHLGSGRWE 4731
Query: 1040 EIAEALS-----------------RPGREACLEARA-------HTGDGAKPDSPQKETLE 1075
+ ALS +P LE G G++ +
Sbjct: 4732 QEDRALSPVIPLIPRASIPVFPDTKPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAA 4791
Query: 1076 VENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTP 1135
G + +A+ + P++P A E + P +E+GL GKS P
Sbjct: 4792 AAKNLNGVMVAVAELLSMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGKEKGLEGKS-P 4850
Query: 1136 EPTLPSAVATEASLDSCP-ESSVGAVSSLDRGCPDAPAPT----SAPTSQQPEPVLGLGS 1190
+ +A L +S + +S L + P PT + S L
Sbjct: 4851 DTGPDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPP 4910
Query: 1191 VEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCL 1250
E+P PS L PP P+ P+ +P P L A+ P P P
Sbjct: 4911 PEEPSPPPSPLAPSPASPPTEPLVELPTEPL-----AEPPVPSPLPLASSPESARPKP-R 4964
Query: 1251 CQDPQEDSVEDEEPP 1265
+ P+E ED PP
Sbjct: 4965 ARPPEEG--EDSRPP 4977
Score = 39.7 bits (91), Expect = 0.023
Identities = 202/1000 (20%), Positives = 307/1000 (30%), Gaps = 167/1000 (16%)
Query: 501 RVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQESVTAEKLPTPQE--ETSLTLC 558
R+ PQ G + A + + P + G A +P P E L L
Sbjct: 2105 RIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLP 2164
Query: 559 PDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPK 618
P P + + P G P A + PR T P + T P Q L ++ +
Sbjct: 2165 PQVPAQVPSQD----PFGLAP--AYPLEPRFPTAPPTYPPYPSPTGA-PAQPPMLGASSR 2217
Query: 619 PVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQ 678
P A G Q S P L + L + P + + +E L+ P
Sbjct: 2218 PGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPP 2277
Query: 679 DSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPK 738
L ++ +L ++ L + P L L+ D+ AP
Sbjct: 2278 FGESRKALEVKKEELGASSPSYGPPNLGFVDS------PSSGTHLGGLELKTPDVFKAPL 2331
Query: 739 PVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTL-- 796
A+ + Q GL PQ+ PP S P + A+ LT
Sbjct: 2332 TPRASQVEPQSPGLGLR-PQEP---PPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRP 2387
Query: 797 ----PQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTD 852
P+ PP L S P A+ SQ + + P+ + P T
Sbjct: 2388 QPPPPESCCALPPRSLPSDPFSRVP-----ASPQSQSSSQSPLTPRPLSAEAFCPSPVTP 2442
Query: 853 LSSAPKPVAAATPVSQQAEEGLTLPQDSAMTPPL------PLQDTDLSSAPKPVAAATPV 906
+P P + Q + L + PP L T L + P AA P
Sbjct: 2443 RFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFP--AALPA 2500
Query: 907 SQQAEEGLTLPQDSA------------MTAPLPLQDTGPTSGPEPL--------AVATPQ 946
E +P + P P++ T P + EP + P
Sbjct: 2501 GPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPH 2560
Query: 947 TLQAEAGCAPG-------TEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQ 999
+ + G P VAT G LGP ++ L + P+ L
Sbjct: 2561 GINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVL---- 2616
Query: 1000 QDDPQPAAEAGTPWAAQEDAD-STLGMEALSLPEPASGAGEEIAEALSRPGREACLEARA 1058
P PA + P+ + + S + +P +G G +A A ++ + +
Sbjct: 2617 ---PPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLS 2673
Query: 1059 HTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDA------------ 1106
T + ++ E+ +Q+ L QE +A GA P +
Sbjct: 2674 QTE--LEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQ 2731
Query: 1107 ------PPAACPEVSQARLLSPAREERGLSGK----STPEPTLPSAVATEASLDSCPESS 1156
P A + S L P++ + G S + P AT +S+D
Sbjct: 2732 LSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPATPSSMDVNSRQL 2791
Query: 1157 VGAVSSLDRGCPDAPAPTSAPTSQQPEPV-----------------LGLGSVEQPHEVPS 1199
VG + + AP P S P QQ + + S P
Sbjct: 2792 VGGSQAFYQR---APYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQ 2848
Query: 1200 VLGTPLLQPPENLAKGQPSTPVDRPLGPDP------------SAPGTLAGAALPPLEPPA 1247
LG+PL L P PV P GP GT PP P
Sbjct: 2849 ALGSPLAGISTRLPG--PGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRF 2906
Query: 1248 PCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPA---------AAAVSGTTQPLGTGPRVS 1298
+ +DP + E GLPP + PA G T P G V+
Sbjct: 2907 YPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNSLHPTPHTKGPTLPTGL-ELVN 2965
Query: 1299 LSPHSPLLS-PKVASMDAKDLALQILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLE- 1356
P S L P +++A L PC + P A + ED++ L
Sbjct: 2966 RPPSSTELGRPNPLALEAGKL------PC--------EDPELDDDFDAHKALEDDEELAH 3011
Query: 1357 ----------EDSPRALGSGQHSDSHGESSAELDEQDILA 1386
+D L + + +D H + DE D+LA
Sbjct: 3012 LGLGVDVAKGDDELGTLENLETNDPHLDDLLNGDEFDLLA 3051
Score = 35.0 bits (79), Expect = 0.57
Identities = 36/128 (28%), Positives = 51/128 (39%), Gaps = 18/128 (14%)
Query: 132 PRAARTALRDQEGGHASPDPPP---ELCSQGDLSVPSPPPDPDSFFTPPSTPTKTTYALL 188
P ++ LR G A P P +L ++ +LS P PP PPS K +
Sbjct: 4584 PVNGQSQLRGAFGSGALPTGPDYYSQLLTKNNLSNPPTPPSSLPPTPPPSVQQKMVNGVT 4643
Query: 189 PA--CGPH----GDARDSEAELRD-------ELLDSPPASPSGSY--ITADGDSWASSPS 233
P+ G H ARDSE LRD +LL + P P + + D + SP
Sbjct: 4644 PSEELGEHPKDAASARDSERALRDTSEVKSLDLLAALPTPPHNQTEDVRMESDEDSDSPD 4703
Query: 234 CSLSLLAP 241
+ +P
Sbjct: 4704 SIVPASSP 4711
Score = 34.7 bits (78), Expect = 0.74
Identities = 46/174 (26%), Positives = 63/174 (36%), Gaps = 16/174 (9%)
Query: 112 PATLEPRIVMGEETCQALLSPRAARTALRDQEGGHASPDPPPELCSQGDLSVPSPPPDPD 171
P P I +G T A LS +A L+ G PD P EL + VP+ P D
Sbjct: 2117 PPAAAPTIFIGSPTTPAGLST-SADGFLKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQD 2175
Query: 172 SFFTPPSTPTKTTYALLPACGPHGDARDSEAELRDELLDS---PPASPSGSYITADGDSW 228
F P+ P + + P P + + A + +L + P A G + T +
Sbjct: 2176 PFGLAPAYPLEPRFPTAPPTYPPYPS-PTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTP 2234
Query: 229 ASSPSCSLSLLAP----AEGLDFPSGWGLSPQGSMVDERELHPAGTPEPPSSES 278
PS L P + L P G+ G E L P PP ES
Sbjct: 2235 RHQPSTPDPFLKPRCPSLDNLAVPESPGVG--GGKASEPLLSP-----PPFGES 2281
Score = 32.3 bits (72), Expect = 3.7
Identities = 69/269 (25%), Positives = 96/269 (35%), Gaps = 57/269 (21%)
Query: 44 ALTPGPSHLALTFLP-------SKPGARPQPEGASWDAGPGGAPSAWADPGEGGPSPML- 95
AL P P F P ++P P+P+ P S A P PS
Sbjct: 2357 ALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQ-------PPPPESCCALPPRSLPSDPFS 2409
Query: 96 -LPEGLSSQALSTEAPLPATLEPRIVMGEETCQALLSPRAARTALRDQEGGHASPDP--- 151
+P SQ+ S+++PL PR + E C + ++PR SPDP
Sbjct: 2410 RVPASPQSQS-SSQSPLT----PRPLSAEAFCPSPVTPR------------FQSPDPYSR 2452
Query: 152 PPELCSQGD----LSVPSPPPDPDSFFTPPSTP-TKTTYALLPACGPHGDARDSEAELRD 206
PP D L P P P+ F S T PA P G A + A++
Sbjct: 2453 PPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPS 2512
Query: 207 ELLDSPPASP-SGSYITADGDSWASSPSC----SLSLLAPAEGLDFPSGWGL-------- 253
+ SP +G+++ + P SL P GL P G
Sbjct: 2513 GQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTL 2572
Query: 254 -SPQGS--MVDERELHPAGTPEPPSSESS 279
PQ + V HP+G+P PSS S+
Sbjct: 2573 GKPQSTNYTVATGNFHPSGSPLGPSSGST 2601
Score = 31.2 bits (69), Expect = 8.2
Identities = 83/340 (24%), Positives = 111/340 (32%), Gaps = 37/340 (10%)
Query: 13 PEADRPGPRTDLSCDAAAATTILGGDRREPCALTPGPSHLALTFLPSKPGARPQPEGASW 72
PEA R P + S + E L P L+ P + P PE +
Sbjct: 567 PEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRL 626
Query: 73 DAGPGGAPSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIVMGEETCQALLSP 132
P +P + P E SP PE +S +PLP R+ E P
Sbjct: 627 SPPPEDSPMS-PPPEESPMSPP--PE------VSRLSPLPVV--SRLSPPPEESPLSPPP 675
Query: 133 RAARTALRDQEGGHASPDPPPELCSQGDLSVPSPPPDPDSFFT-----PPSTPTKTTYAL 187
+ T+ E SP P S P+ PP DS + P P L
Sbjct: 676 EESPTS-PPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQL 734
Query: 188 LPAC-GPHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLAPAEGLD 246
P GPH R E L + P SP A+ + P P E
Sbjct: 735 CPRSEGPHLSPRPEEPHLSPR-PEEPHLSPQ-----AEEPHLSPQPEEPCLCAVPEEPHL 788
Query: 247 FPSGWG--LSPQGSMVDERELHPAGTPEPPSSESSLSADSSSSWGQEGHFFDLDFLANDP 304
P G LSPQ ELH + E P S +E H L + +P
Sbjct: 789 SPQAEGPHLSPQ-----PEELHLSPQTEEPHLSPVPEEPCLSPQPEESH---LSPQSEEP 840
Query: 305 MIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEEAVADPDP 344
+ P + L ++E ++P PE+ EE P P
Sbjct: 841 CLSPR--PEESHLSPELEKPPLSP-RPEKPPEEPGQCPAP 877
>gi|91982772 mucin 17 [Homo sapiens]
Length = 4493
Score = 102 bits (253), Expect = 4e-21
Identities = 215/954 (22%), Positives = 341/954 (35%), Gaps = 167/954 (17%)
Query: 509 EETDSTAGQESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLT------------ 556
E+T S E + M PS+E IS + V+ LP+ + TSLT
Sbjct: 134 EDTSSPTTPEGTDVPMSTPSEESISSTMA--FVSTAPLPSFEAYTSLTYKVDMSTPLTTS 191
Query: 557 -------LCPDS---PQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQD------- 599
P+S P++ EG L S P + + +A LT P +
Sbjct: 192 TQASSSPTTPESTTIPKSTNSEGSTPLTS--MPASTMKVASSEAITLLTTPVEISTPVTI 249
Query: 600 --SAMTPPLPLQDTDLS-SAPK---------PVAAATIVSQQAEEGLTLPQDSVMTPPLP 647
A + P + LS SAP P++ +VS +A TL T
Sbjct: 250 SAQASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEAS---TLSTTPAATNIPV 306
Query: 648 LQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSS-APKPVAAATLV 706
+ TE SS+P ++ + EG T P S +P+ +++S+ + PV +TLV
Sbjct: 307 ITSTEASSSPTTAEGTSIPTSTYTEGST-PLTSTPASTMPVATSEMSTLSITPVDTSTLV 365
Query: 707 SQQAEEG---LTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDS--- 760
+ E T S +T L T L++ PV+ + S +A T+P DS
Sbjct: 366 TTSTEPSSLPTTAEATSMLTSTLSEGSTPLTN--MPVSTILVASSEASTTSTIPVDSKTF 423
Query: 761 ------AMTPPLPLQDTDLSSA----------PKPVAAATIVSQQAEEGLTLPQDSAMTP 804
A + P +DT ++++ PV+ + S +A T P DS
Sbjct: 424 VTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQ- 482
Query: 805 PLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSS-APKPVAAA 863
T+ SS+P ++ + EG T P S +P+ ++ S+ + PV +
Sbjct: 483 --VTTSTEASSSPPTAEVNSMPTSTPSEGST-PLTSMSVSTMPVASSEASTLSTTPVDTS 539
Query: 864 TPV--SQQAEEGLTLPQDSAMTPPLPLQ-DTDLSSAPKPVAAATPVSQQAEEGLTLPQDS 920
TPV S +A T P+ +++ P + T L++ PV+ VS +A T P DS
Sbjct: 540 TPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTN--MPVSTRLVVSSEASTTSTTPADS 597
Query: 921 AMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPE 980
+ + ++ E + P + +E G + V+T EA P
Sbjct: 598 NTFVTTSSEASSSSTTAE--GTSMPTSTYSERGTTITSMSVSTTLVAS-SEASTLSTTPV 654
Query: 981 EKNAALPTVPEPAALDQVQQDDPQPAA---EAGTP---------WAAQEDADS------- 1021
+ N + T E + + P + E TP A +A +
Sbjct: 655 DSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVD 714
Query: 1022 -----TLGMEALSLPEPASGA-------GEEIAEALSRPGREACL-EARAHTGDGAKPDS 1068
T EA S P A GA E S P + L + A T D+
Sbjct: 715 TSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDT 774
Query: 1069 PQKETLEVE-----NQQEGGLKPLAQEHGPRSALGGAREVP-DAPPAACPEVSQARLL-- 1120
T E EG P++ P +P P PE S
Sbjct: 775 STHITTSTEASCSPTTTEGTSMPIST---PSEGSPLLTSIPVSITPVTSPEASTLSTTPV 831
Query: 1121 ---SPAREERGLSGKSTPE--PTLPSAVATE--ASLDSCPES----SVGAVSSLDRGCPD 1169
SP +S TP ++P++ +E L S P S + A+S+L D
Sbjct: 832 DSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVD 891
Query: 1170 APAPTSAPTSQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPENL-------AKGQPSTPVD 1222
P + T + P G+ P P TPL P++ A+ +TPVD
Sbjct: 892 TSTPVTNSTEARSSPTTSEGT-SMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVD 950
Query: 1223 --RPLGPD---PSAPGTLAGAALP---PLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQ 1274
P+ S+P T G ++P P E P L P ++ +L P
Sbjct: 951 TSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTP-LTSTPVSHTLVANSEASTLSTTPVD 1009
Query: 1275 AGVQPAAAAVSGTTQPLGTGPRVSLSPHS---------PLLSPKVASMDAKDLA 1319
+ + + + P G + S S P+ + VAS + L+
Sbjct: 1010 SNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLS 1063
Score = 99.0 bits (245), Expect = 3e-20
Identities = 223/1083 (20%), Positives = 371/1083 (34%), Gaps = 138/1083 (12%)
Query: 468 VTEEGLALGQESTATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQP 527
V+ +A + ST + TP V+ + VT + +TA S ++ P
Sbjct: 2876 VSTTPVASSEASTLSTTP----------VDTSIPVTTSTEGSSSPTTAEGTSMPISTPSE 2925
Query: 528 SQEGISEIL-------GQESVTAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSG---- 576
++ IL G E+ T P T +T ++ + G +P
Sbjct: 2926 VSTPLTSILVSTVPVAGSEASTLSTTPV-DTRTPVTTSAEASSSPTTAEGTSMPISTPGE 2984
Query: 577 -RKPVAAATI--VPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEG 633
R P+ + ++ +P + E TL + A T T+ SS+P I EG
Sbjct: 2985 RRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEG 3044
Query: 634 LT-LPQDSVMTPPLPLQDTE-LSSAP----KPVAAATLVSQQAE--EGLTLPQDSAMTPP 685
T L V T P+ + + LS+ P PV +T VS EG ++P +
Sbjct: 3045 STPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGS 3104
Query: 686 LPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATL 745
PL +S+ P +A + +S T P D++ TP T+ S+P ++
Sbjct: 3105 TPLTGVPVSTTPVTSSAISTLS-------TTPVDTS-TPVTT--STEAHSSPTTSEGTSM 3154
Query: 746 VSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAE-------EGLTLPQ 798
+ EG T ++ L + D + + PV +T V+ E EG ++P
Sbjct: 3155 PTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPT 3214
Query: 799 DSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEG---LTLPQDSAMTPP------LPLQ 849
+ PL +S+ P + A+I+S + LT +++ +PP +P
Sbjct: 3215 STPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTS 3274
Query: 850 DTDLSSAP---KPVAAATPVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAAT-- 904
S P PV+ T S + T P D++ P+ +S+ P+A T
Sbjct: 3275 TPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTST----PVTTYSQASSSPPIADGTSM 3330
Query: 905 PVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPVATM 964
P S +E L S T P+ + T P+ +TP T EA +P T ++
Sbjct: 3331 PTSTYSEGSTPLTNMSFSTTPV-VSSEASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSI 3389
Query: 965 AQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLG 1024
E P A++P P +V P + E + S
Sbjct: 3390 PTSSPSEGTTPL-------ASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTI 3442
Query: 1025 MEALSLPEPASGAG---------------EEIAEALSRPGREACLEARAHTGDGAKPDSP 1069
E SLP + G A LS + + + P +
Sbjct: 3443 AEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTA 3502
Query: 1070 QKETLEVENQQEGGL----KPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPARE 1125
+ ++ EG P++ S P SQA SPA
Sbjct: 3503 EVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQAS-SSPATL 3561
Query: 1126 ERGLSGKSTPEPTLPS--AVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPE 1183
+ STP S + ++ + E+S + S+DR P + S T PE
Sbjct: 3562 QVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPPE 3621
Query: 1184 PVLGLGSVEQPHEVPSVLGTPLLQPPENLAK------GQPST-PVDRPL-----GPDPSA 1231
+ P PS + TPL P + G ST PVD S+
Sbjct: 3622 ------VITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSS 3675
Query: 1232 PGTLAGAALP---PLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAAAAVSGTT 1288
P T G +P P E P V E GS P P V+ +T
Sbjct: 3676 PVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSE--GSTLSTPSVVTSTP----VTTST 3729
Query: 1289 QPLGTGPRVSLSPHSPLLSPKVASMDAKDLALQILPPCQVPPPSGPQSPAGPQGLSAPEQ 1348
+ + + + + S + +++++ + + P + P S P P+ +S
Sbjct: 3730 EAISSSATLDSTTMSVSMPMEISTL-GTTILVSTTPVTRFPESSTPSIPSVYTSMSMTTA 3788
Query: 1349 QEDEDSLEEDSPRAL-GSGQHSDSHGESSAELDEQDILAPQTVQCPAQA------PAGGS 1401
E SP L G+ S + L +++P +V P++A P S
Sbjct: 3789 SEG-----SSSPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLSTPPGDTS 3843
Query: 1402 EETIAKAKQSRSEKKARKAMSKLGLRQIQGVTRITIQKSKNILFVIAKPDVFKSPASDTY 1461
+ K A ++ + + T+ S + + +P DT
Sbjct: 3844 TPLLTSTKAGSFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPGASIASTPPLDTS 3903
Query: 1462 VVF 1464
F
Sbjct: 3904 TTF 3906
Score = 93.6 bits (231), Expect = 1e-18
Identities = 278/1320 (21%), Positives = 453/1320 (34%), Gaps = 193/1320 (14%)
Query: 165 SPPPDPDSFFTPPSTPTKTTYALLPACGPHGDARDSEAELRDELLDSPPASPSGSYITAD 224
S P + P STP++ T L H +SEA L + P S + +T
Sbjct: 963 SSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEAST----LSTTPVD-SNTPLTTS 1017
Query: 225 GDSWASSPSC---SLSLLAPAEGLDFPSGWGLSPQ---GSMVDERELHPAGTPEPPSSES 278
++ + P+ S+ P+EG + +S S PA T P ++ S
Sbjct: 1018 TEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYS 1077
Query: 279 SLSADSSSSWGQEGHFFDLDFLANDPMIPAALLPFQGSLIFQVEA--VEVTPLS---PEE 333
S+ S+++ G ++ P +P L+ EA + TP+ P
Sbjct: 1078 QASSSSTTADGTSMPTSTY----SEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVT 1133
Query: 334 EEEEAVADPDPGGDLAGEGEEDSTSASFLQSLSDLSITEGMDEAFAFR-----DDTSAAS 388
EA + P + S + L S+ + EA T A+
Sbjct: 1134 TSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVAT 1193
Query: 389 SDSDSASYAEADDERLYSGEPHAQATLLQDSVQKTEEESGGGAKGLQAQDGTVSWAVEAA 448
S S+ A+ + + P ++T L + + A L S V +
Sbjct: 1194 STEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTS 1253
Query: 449 PQTSDRGAYLSQRQELISEVTEEGLAL-------------GQESTATVTPHTLQVAPGLQ 495
+TS ++ L + T EG L + ST TP +
Sbjct: 1254 AETSSSPT-TAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTS 1312
Query: 496 VEVATRVTPQAGEEETDSTAGQESAAM-AMPQPSQEGISEILGQESVTAEKLPTPQEETS 554
EV++ TP G ST + + ++P + S + S T TP TS
Sbjct: 1313 NEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVT-TS 1371
Query: 555 LTLCPDS--------PQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPL 606
C P + EG L S PV+ +V +A P D+
Sbjct: 1372 TEACSSPTTSEGTSMPNSNPSEGTTPLTS--IPVSTTPVVSSEASTLSATPVDT------ 1423
Query: 607 PLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLV 666
S P +A S EG+++P + PL+ +S+ P + A+ +
Sbjct: 1424 --------STPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTL 1475
Query: 667 SQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPL 726
S T P DS P+ + T +SS+P P ++ EG T A+T +
Sbjct: 1476 S-------TTPVDS--NSPV-VTSTAVSSSPTPAEGTSIAISTPSEGST-----ALTS-I 1519
Query: 727 PLQDTDLSSAP------KPVAAATLV---SQQAEEGLTLPQDSAMTPPLPLQDTDLSSAP 777
P+ T ++S+ P +T V SQ + T S T T L+S P
Sbjct: 1520 PVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLP 1579
Query: 778 KPVAAATIVSQQAEEGLTLPQDS-------------------AMTPPLPLQDTDLSSAPK 818
V+ +VS +A T P DS +MT P + + L ++
Sbjct: 1580 --VSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPLLTSI- 1636
Query: 819 PVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQ 878
PV+ + S +A T P DS P+ + T++SS+P P + + EG T P
Sbjct: 1637 PVSTTPVASPEASTLSTTPVDS--NSPV-ITSTEVSSSPTPAEGTSMPTSTYTEGRT-PL 1692
Query: 879 DSAMTPPLPLQDTDLSS-APKPVAAATPVSQQAE--------EGLTLPQDSAMTAPLPLQ 929
S P+ + +S+ + PV +TPV+ E EG ++P + PL
Sbjct: 1693 TSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLT 1752
Query: 930 DTGPTSGP-----------EPLAVATPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPA 978
++ P P+ +TP T EA +P T ++ + E + P +
Sbjct: 1753 SIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTS 1812
Query: 979 --------PEEKNAALPTVP----EPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGME 1026
+ + L T P P P PA GT A ++ + +
Sbjct: 1813 TPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPA--EGTSIATSTPSEGSTAL- 1869
Query: 1027 ALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKP 1086
S+P + LS + + P + ++ +EG +P
Sbjct: 1870 -TSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREG--RP 1926
Query: 1087 LAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPT-LPSAVAT 1145
+ + E+ + S A S +T + T +P+ +
Sbjct: 1927 PLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQAS-----SSPTTADGTSMPTPAYS 1981
Query: 1146 EAS--LDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPE----PVLGLGSVEQPHEVPS 1199
E S L S P S+ VSS P TS P + E P G+ Q PS
Sbjct: 1982 EGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQT-STPS 2040
Query: 1200 VLGTPLLQPPENL-----AKGQ--PSTPVDRPL----GPDPSAPGTLAGAALPPLEPP-- 1246
TPL P + ++G +TPVD + S+ T G+++ P
Sbjct: 2041 ERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEG 2100
Query: 1247 APCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGT-GPRVSLSPHS-- 1303
+P L P + +L P + P + ++ P+ T G + S +S
Sbjct: 2101 SPLLTSIPLSTTPVASPEASTLSTTPVDSN-SPVITSTEVSSSPIPTEGTSMQTSTYSDR 2159
Query: 1304 --PLLSPKVASMDAKDLALQIL--PPCQVPPP-----SGPQSPAGPQGLSAPEQQEDEDS 1354
PL S V++ A+ L P P SP +G S P E S
Sbjct: 2160 RTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGS 2219
Score = 91.3 bits (225), Expect = 7e-18
Identities = 325/1483 (21%), Positives = 496/1483 (33%), Gaps = 237/1483 (15%)
Query: 63 ARPQPEGASWDAGPGGAPSAWADPGEGGP---SPMLLPEG--LSSQALSTEAPLP----A 113
AR P + + P PS P P +P+L E LS+ + T P+ A
Sbjct: 1727 ARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEA 1786
Query: 114 TLEPRIVMG--------EETCQALLSPRAARTALRDQEGGHASPDP----PPELCSQGDL 161
T P G E L S + T + + E S P P + S
Sbjct: 1787 TSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVS 1846
Query: 162 SVPSPPPDPDSFFTPPSTPTKTTYAL--LPACGPHGDARDSEAELRDELLDSPP----AS 215
S P+P + STP++ + AL +P + ++ + S P A
Sbjct: 1847 SSPTPA---EGTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQ 1903
Query: 216 PSGSYITADGDSWASSPSCSLSLLAPAEGLDFPSGWGLSPQGSMVDERELHPAGTP--EP 273
S S TADG S +S P EG P + + V E++ T +
Sbjct: 1904 VSSSPTTADGSSMPTS--------TPREGR--PPLTSIPVSTTTVASSEINTLSTTLADT 1953
Query: 274 PSSESSLSADSSSSWGQEGHFFDLDFLANDPMIPAALLPFQGSLIFQVEA--VEVTPL-- 329
+ ++ S SSS +G + + P +P +L+ EA + TP+
Sbjct: 1954 RTPVTTYSQASSSPTTADGTSMPTPAYS-EGSTPLTSMPLSTTLVVSSEASTLSTTPVDT 2012
Query: 330 -SPEEEEEEAVADPDPGGDLAGEGEEDSTSASFLQSLSDLSIT-------EGMDEAFAFR 381
+P E + P G G + ST + L+ + ++ EG +
Sbjct: 2013 STPATTSTEGSSSPTTAG---GTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLSTTPV 2069
Query: 382 DDTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSVQKTEEESGGGAKGLQA----- 436
D + ++ ++++S A A+ + P + LL T + A L
Sbjct: 2070 DSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVASPEASTLSTTPVDS 2129
Query: 437 -QDGTVSWAVEAAPQTSD-----RGAYLSQRQELIS-EVTEEGLALGQESTATVTPHTLQ 489
S V ++P ++ Y +R L S V+ +A ST + TP
Sbjct: 2130 NSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTS 2189
Query: 490 VAPGLQVEVATRVTPQAGEEETDSTAGQESAAM-AMPQPSQEGISEILGQESVTAEKLPT 548
E + T G ST + S +MP + ++ S T T
Sbjct: 2190 TPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTST 2249
Query: 549 P-QEETSLTLCPDS------PQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDSA 601
P T T P + P + EG L S PV+ + + T P DS
Sbjct: 2250 PVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTS--IPVSHTLVANSEVSTLSTTPVDSN 2307
Query: 602 MTPPLPLQDTDLSSAPKPVAAATIV--SQQAEEGLTLPQDSVMTPPLPLQDTE-LSSAPK 658
P + +S+P P A T + S +E L + V T + +T LS+ P
Sbjct: 2308 T----PFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPA 2363
Query: 659 PVAAATLVSQQAEEGLTLPQDSAM-TPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLP 717
+ QA T D++M T T L+S P V+ +VS +A T P
Sbjct: 2364 DTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVP--VSTMPVVSSEASTHSTTP 2421
Query: 718 QDS---------AMTPPLPLQDTDLSSAPK----------PVAAATLVSQQAEEGLTLPQ 758
D+ A + P + T + ++P PV+ +VS +A T P
Sbjct: 2422 VDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPV 2481
Query: 759 DSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAM--TPPLPLQDTDLSSA 816
D++ TP T+ SS+P + A EG TL + TP + + LS+
Sbjct: 2482 DTS-TPMTT--STEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEASTLSTT 2538
Query: 817 P----KPVAAATIVSQQAE--EGLTLPQDSAMTPPLPLQDTDLSSAP-----------KP 859
P PV +T +S A EG ++P + PL+ +S+ P P
Sbjct: 2539 PVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTTP 2598
Query: 860 VAAATPVSQQAEEGL--TLPQDSAMTPPLPLQ-DTDLSS---APKPVAAA-------TPV 906
V + PV+ E T +D++M P + T L+S + PVA++ TPV
Sbjct: 2599 VDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPV 2658
Query: 907 --------------SQQAEEGLTLPQDSAMTAPLPLQDT-----------GPTSGPEPLA 941
S EG ++P + PL + T P+
Sbjct: 2659 DTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVD 2718
Query: 942 VATPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQD 1001
+TP T AEA +P T +M + G P + LP A+
Sbjct: 2719 TSTPVTTSAEASSSPTTAEGTSMRISTPSD--GSTPLTSILVSTLPVASSEASTVSTTAV 2776
Query: 1002 DPQPAAEAGTPWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTG 1061
D T E + S E S+ P S E S P + A +
Sbjct: 2777 DTSIPVTTST-----EASSSPTTAEVTSM--PTSTPSETSTPLTSMPVNHTPV---ASSE 2826
Query: 1062 DGAKPDSPQKETLEVENQQEGGLKPLAQEH---GPRSALGGAREVPDAPPAACPEV-SQA 1117
G +P + V + P E +A G+ + P + P S+A
Sbjct: 2827 AGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEA 2886
Query: 1118 RLLSP---------AREERGLSGKSTPEPT-LPSAVATEAS--LDSCPESSVGAVSSLDR 1165
LS G S +T E T +P + +E S L S S+V S
Sbjct: 2887 STLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEAS 2946
Query: 1166 GCPDAPAPTSAPTSQQPE-------------PVLGLGSVEQPHEVPSVLGTPLLQPPENL 1212
P T P + E P+ G P SV P+ +
Sbjct: 2947 TLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEAST 3006
Query: 1213 AKGQP---STPVDRPLGPDPSAPGTLAGAALP---PLEPPAPCLCQDP--------QEDS 1258
P STPV S+P T G +P P E P L P E S
Sbjct: 3007 LSRTPADTSTPVTTSTEAS-SSPTTAEGTGIPISTPSEGSTP-LTSIPVSTTPVAIPEAS 3064
Query: 1259 VEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDL 1318
P S V + GT+ P+ T S +PL V++
Sbjct: 3065 TLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGS----TPLTGVPVSTTPVTSS 3120
Query: 1319 ALQIL--PPCQVPPP-----SGPQSPAGPQGLSAPEQQEDEDS 1354
A+ L P P SP +G S P E S
Sbjct: 3121 AISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGS 3163
Score = 89.4 bits (220), Expect = 3e-17
Identities = 263/1192 (22%), Positives = 402/1192 (33%), Gaps = 158/1192 (13%)
Query: 211 SPPASPSGSYITADGDSWASSPSCSLSLLAPAEGLDFPSGWGLSPQGSMVDERELHPAGT 270
S P +P + I +S S+P S+ PA + S ++ T
Sbjct: 196 SSPTTPESTTIPKSTNSEGSTPLTSM----PASTMKVASSEAITL------------LTT 239
Query: 271 PEPPSSESSLSADSSSS-WGQEGHFFDLDFLANDPMIPAALLPFQGSLIFQVEA--VEVT 327
P S+ ++SA +SSS EG + + P +P L+ EA + T
Sbjct: 240 PVEISTPVTISAQASSSPTTAEGPSLS-NSAPSGGSTPLTRMPLSVMLVVSSEASTLSTT 298
Query: 328 PLS---PEEEEEEAVADPDPGGDLAGEGEEDSTSASFLQSLSDLSITEGMDEAFAFRDDT 384
P + P EA + P EG TS + TEG + T
Sbjct: 299 PAATNIPVITSTEASSSPT-----TAEGTSIPTS----------TYTEGSTPLTSTPAST 343
Query: 385 S-AASSDSDSASYAEADDERLY--SGEPHAQATLLQDSVQKTEEESGGGAKGLQAQDGTV 441
A+S+ + S D L S EP + T + + T S G T+
Sbjct: 344 MPVATSEMSTLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTI 403
Query: 442 SWAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQESTATVTPHTLQVAPGLQVEVATR 501
A A TS SE + S AT TP P + V+T
Sbjct: 404 LVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGST-PLTSMPVST- 461
Query: 502 VTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQESVTAEKLPTPQE-ETSLTLCPD 560
TP A E ++ + + + ++ S + V + TP E T LT
Sbjct: 462 -TPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAE--VNSMPTSTPSEGSTPLTSMSV 518
Query: 561 SPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQ-DTDLSSAPKP 619
S + L + + +A T P+ +++ P + T L++ P
Sbjct: 519 STMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMP-- 576
Query: 620 VAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQD 679
V+ +VS +A T P DS + + S+ + + T S +E G T+
Sbjct: 577 VSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPT--STYSERGTTITSM 634
Query: 680 SAMTPPLPLQDTD-LSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPK 738
S T + + LS+ P S +A T + ++M P +
Sbjct: 635 SVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSM-PTSTYTEGSTPLTSM 693
Query: 739 PVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQ 798
PV + S +A T P D++ TP T+ SS+P A++ + EG T
Sbjct: 694 PVNTTLVASSEASTLSTTPVDTS-TPVTT--STEASSSPTTADGASMPTSTPSEGSTPLT 750
Query: 799 DSAMTPPL--PLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSA 856
++ L + + LS+ P + S +A T + ++M P + + L ++
Sbjct: 751 SMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTS 810
Query: 857 PKPVAAATPVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTL 916
PV+ S +A T P DS P+ T++SS+P P + + EG T
Sbjct: 811 I-PVSITPVTSPEASTLSTTPVDS--NSPVTTS-TEVSSSPTPAEGTSMPTSTYSEGRTP 866
Query: 917 PQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPVATMAQQEVGEALGPR 976
++ L T P+ +TP T EA +P T +M P
Sbjct: 867 LTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSM----------PT 916
Query: 977 PAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADS--TLGMEALSLPEPA 1034
P E + L ++P+ P ++EA T A D + T EA S P A
Sbjct: 917 STPGEGSTPLTSMPDSTT--------PVVSSEARTLSATPVDTSTPVTTSTEATSSPTTA 968
Query: 1035 SGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPR 1094
G + S P G +P TL V N + L +
Sbjct: 969 EGT----SIPTSTPSE----------GTTPLTSTPVSHTL-VANSEASTLSTTPVD--SN 1011
Query: 1095 SALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPE 1154
+ L + E PP A G S P T PS +T L P
Sbjct: 1012 TPLTTSTEASSPPPTA-------------------EGTSMPTST-PSEGST--PLTRMPV 1049
Query: 1155 SSVGAVSSLDRGCPDAPAPTSAPT---SQQPEPVLGLGSVEQPHEVPSVLGTPLLQPP-- 1209
S+ SS PA TS P SQ P S TPL P
Sbjct: 1050 STTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVS 1109
Query: 1210 -----ENLAKGQPSTPVDRPL-----GPDPSAPGTLAGAAL---PPLEPPAPCLCQDPQE 1256
+ A +TPVD + S+P T G ++ PP E P L P
Sbjct: 1110 TRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTP-LASMPVS 1168
Query: 1257 DSVEDEEPPGSLGLPPPQAGVQPAAAAVSG--------TTQPLGT-GPRVSLSPHSPLLS 1307
++ +L P + Q A + + T+ P T G R + P+
Sbjct: 1169 TTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRH 1228
Query: 1308 PKVASMDAKDLALQILPPCQVPPP-----SGPQSPAGPQGLSAPEQQEDEDS 1354
VAS +A L+ P P SP +G S P E S
Sbjct: 1229 TPVASSEASTLSTS---PVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGS 1277
Score = 84.7 bits (208), Expect = 6e-16
Identities = 255/1236 (20%), Positives = 412/1236 (33%), Gaps = 147/1236 (11%)
Query: 88 EGGPSPMLLPEGLS---SQALSTEAPLPATLEPRI-VMGEETCQALLSPRAARTALRDQE 143
EG SP EG S S PL + L + V G E +P RT +
Sbjct: 2905 EGSSSPTTA-EGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTS- 2962
Query: 144 GGHASPDPPPELCSQGDLSVPSPPPDPDSFFTPPSTPTKTTYALLPACGPHGDARDSEAE 203
AS P + +S P P + + + P ++ A + P A S
Sbjct: 2963 -AEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTP---ADTSTPV 3018
Query: 204 LRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLAPAEGLDFPSGWGLSPQGS---MV 260
S P + G+ I S S+P S+ + + S +P S +V
Sbjct: 3019 TTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVV 3078
Query: 261 DERELHPAGTPEPPSSESSLSADSSSSWGQEGHFFDLDFLANDPMIPAALLPFQGSLIFQ 320
E+ + TP +S +S S S G +P + P S I
Sbjct: 3079 TSTEVSSSPTPAEGTS-MPISTYSEGSTPLTG-------------VPVSTTPVTSSAIST 3124
Query: 321 VEAVEVTPLSPEEEEEEAVADPDPGGDLA---GEGEEDSTSASFLQSLSDLSITEGMDEA 377
+ V +P EA + P + E ST +++ + L ++
Sbjct: 3125 LSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTL 3184
Query: 378 FAFRDDTSA-ASSDSDSASYAEADDERLYSGEPHAQATLLQDSVQKTEEESGGGAKGLQA 436
A DTS ++ +++ S A+ + + P T L + A L
Sbjct: 3185 SATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILST 3244
Query: 437 QDGTVSWAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQESTATVTPHTLQVAPGLQV 496
+ + + + S S T EG ++ ST + L P
Sbjct: 3245 TPVDSNTPLTTSTEASS------------SPPTAEGTSM-PTSTPSEGSTPLTSMPVSTT 3291
Query: 497 EVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLT 556
VA+ T D++ + + A P I++ + T + TP S +
Sbjct: 3292 TVASSETSTLSTTPADTSTPVTTYSQASSSPP---IADGTSMPTSTYSEGSTPLTNMSFS 3348
Query: 557 LCP--DSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLS 614
P S + +D + A++ P A E ++P S PL
Sbjct: 3349 TTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTTA-EGTSIPTSSPSEGTTPL------ 3401
Query: 615 SAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGL 674
A PV+ +VS + T P DS L TE SS+P +L + EG
Sbjct: 3402 -ASMPVSTTPVVSSEVNTLSTTPVDS---NTLVTTSTEASSSPTIAEGTSLPTSTTSEG- 3456
Query: 675 TLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPP----LPLQD 730
S +PL T ++S+ + T V + P +S+ T +P
Sbjct: 3457 -----STPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTST 3511
Query: 731 TDLSSAP---KPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVS 787
S P PV+ + S +A T P DS + SS+P + T+
Sbjct: 3512 AGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNT---FVTSSSQASSSPATLQVTTMRM 3568
Query: 788 QQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPP-- 845
EG S++T L L T ++S+ + V + + +S TPP
Sbjct: 3569 STPSEG-----SSSLTTML-LSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPPEV 3622
Query: 846 --LPLQDTDLSSAP---KPVAAATPVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV 900
LP+ S P PV+ + +A TLP D++ TP + T +SS+P
Sbjct: 3623 ITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTS-TPVIT--STQVSSSPVTP 3679
Query: 901 AAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEP 960
T EG T ++ G T + +TP T EA + T
Sbjct: 3680 EGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAISSSATLD 3739
Query: 961 VATMAQQEVGE--------ALGPRPA---PEEKNAALPTVPEPAALDQVQQDDPQPAAEA 1009
TM+ E + P PE ++P+V ++ + P
Sbjct: 3740 STTMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSVYTSMSMTTASEGSSSPTTLE 3799
Query: 1010 GTPWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSP 1069
GT + L P S A LS P + T G+
Sbjct: 3800 GTTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLSTPPGDTSTPLLTSTKAGSFSIPA 3859
Query: 1070 QKETLEVE--NQQEGGLKPLAQEHGPRSALGGAREVPDAPP-------------AACPEV 1114
+ T+ + +++ L L ++ GA + PP A+ P +
Sbjct: 3860 EVTTIRISITSERSTPLTTLLVSTTLPTSFPGA-SIASTPPLDTSTTFTPSTDTASTPTI 3918
Query: 1115 SQARLLSPAREERGLSGKSTPEPT--LPSAVATEASLDSCPESSVGAVSS--LDRGCPDA 1170
A +S + G STP T +PS T ++ D P ++ GAVS+ + +
Sbjct: 3919 PVATTISVSVITEG----STPGTTIFIPSTPVTSSTADVFP-ATTGAVSTPVITSTELNT 3973
Query: 1171 PAPTSAPTSQQPEPVLGLGSVEQPHEVPSVLGTPLLQP--PENLAKG---------QPST 1219
P+ +S+ T+ + P T P P ++G ST
Sbjct: 3974 PSTSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPSTPRTTSRGCTTSASTLSATST 4033
Query: 1220 P------VDRPLGP--DPSAPGTLAGAALPPLEPPA 1247
P RP+ P + S P T+ +PP PPA
Sbjct: 4034 PHTSTSVTTRPVTPSSESSRPSTITSHTIPPTFPPA 4069
Score = 81.6 bits (200), Expect = 5e-15
Identities = 192/878 (21%), Positives = 296/878 (33%), Gaps = 120/878 (13%)
Query: 558 CPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAP 617
C +P+ E + S V++ + P +++ DS P +DT SS
Sbjct: 85 CSTNPEMTSIESSVT--SDTPGVSSTRMTPTESRTTSESTSDSTTLFPSSTEDT--SSPT 140
Query: 618 KPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPK-PVAAATLVSQQAEEGLTL 676
P +S +EE ++ V T PLP + S K ++ S QA T
Sbjct: 141 TPEGTDVPMSTPSEESISSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTT 200
Query: 677 PQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSA 736
P+ + +P S P A+ + + E +TL +T P+ + S
Sbjct: 201 PESTT----IPKSTNSEGSTPLTSMPASTMKVASSEAITL-----LTTPVEI------ST 245
Query: 737 PKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTL 796
P ++A S EG +L + PL P++ +VS +A TL
Sbjct: 246 PVTISAQASSSPTTAEGPSLSNSAPSGGSTPL-------TRMPLSVMLVVSSEAS---TL 295
Query: 797 PQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSS- 855
A T + T+ SS+P +I + EG T P S +P+ +++S+
Sbjct: 296 STTPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGST-PLTSTPASTMPVATSEMSTL 354
Query: 856 APKPVAAATPVSQQAEEG---LTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEE 912
+ PV +T V+ E T S +T L T L++ PV+ S +A
Sbjct: 355 SITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTN--MPVSTILVASSEAST 412
Query: 913 GLTLPQDS---------AMTAPLPLQDTG-----PTSGPEPLA---VATPQTLQAEAGCA 955
T+P DS A ++P +DT P+ G PL V+T +EA
Sbjct: 413 TSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNL 472
Query: 956 PGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPE--------------PAALDQVQQD 1001
T PV + Q P E N+ + P P A +
Sbjct: 473 -STTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTL 531
Query: 1002 DPQPAAEAGTPWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTG 1061
P + + E + S+ E S+P G + R + + A T
Sbjct: 532 STTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTR-LVVSSEASTT 590
Query: 1062 DGAKPDS-----PQKETLEVENQQEGGLKPLA--QEHGPR-SALGGAREVPDAPPAACPE 1113
DS E EG P + E G +++ + + + A+
Sbjct: 591 STTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLS 650
Query: 1114 VSQARLLSP-AREERGLSGKSTPEPT-LPSAVATEAS--LDSCPESSVGAVSSLDRGCPD 1169
+ +P S +T E T +P++ TE S L S P ++ SS
Sbjct: 651 TTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLST 710
Query: 1170 APAPTSAPTSQQPE----PVLGLGSVEQPHEVPSVLGTPLLQPPEN---LAKGQPSTPVD 1222
P TS P + E P G+ P PS TPL P + L + ST
Sbjct: 711 TPVDTSTPVTTSTEASSSPTTADGA-SMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLST 769
Query: 1223 RPLGPD---------PSAPGTLAGAALPPLEPP--APCLCQDP--------QEDSVEDEE 1263
PL +P T G ++P P +P L P E S
Sbjct: 770 TPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTT 829
Query: 1264 PPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLALQIL 1323
P S V + GT+ P T +PL S V++ A+ L
Sbjct: 830 PVDSNSPVTTSTEVSSSPTPAEGTSMPTST----YSEGRTPLTSMPVSTTLVATSAISTL 885
Query: 1324 --PPCQVPPP-----SGPQSPAGPQGLSAPEQQEDEDS 1354
P P SP +G S P E S
Sbjct: 886 STTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGS 923
Score = 46.6 bits (109), Expect = 2e-04
Identities = 88/411 (21%), Positives = 134/411 (32%), Gaps = 75/411 (18%)
Query: 479 STATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEG------- 531
ST VT P + + A E + T + + M M S+
Sbjct: 3761 STTPVTRFPESSTPSIPSVYTSMSMTTASEGSSSPTTLEGTTTMPMSTTSERSTLLTTVL 3820
Query: 532 ISEILGQESVTAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAK 591
IS I A L TP +TS L + + G +P+ + + R
Sbjct: 3821 ISPISVMSPSEASTLSTPPGDTSTPLLTST-----KAGSFSIPAEVTTIRISITSERSTP 3875
Query: 592 -----EDLTLPQDS-----AMTPPLPLQ-----DTDLSSAPKPVAAATIVSQQAEEGLTL 636
TLP A TPPL TD +S P A TI EG T
Sbjct: 3876 LTTLLVSTTLPTSFPGASIASTPPLDTSTTFTPSTDTASTPTIPVATTISVSVITEGST- 3934
Query: 637 PQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSA 696
P ++ P P+ + P A + TP + T+L++
Sbjct: 3935 PGTTIFIPSTPVTSSTADVFPATTGAVS------------------TPVIT--STELNT- 3973
Query: 697 PKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAP---KPVAAATLVSQQAEEG 753
P +++T S + T P AMT PL +S+AP + + S
Sbjct: 3974 PSTSSSSTTTSFSTTKEFTTP---AMTTAAPLTYVTMSTAPSTPRTTSRGCTTSASTLSA 4030
Query: 754 LTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPL------- 806
+ P S P+ + SS P + + TI T P + TPP
Sbjct: 4031 TSTPHTSTSVTTRPVTPSSESSRPSTITSHTIPP-------TFPPAHSSTPPTTSASSTT 4083
Query: 807 --PLQDTDLSSAPKP----VAAATIVSQQAEEGLTLPQDSAMTPPLPLQDT 851
P T +++ KP + T+ + T+ + TP +P T
Sbjct: 4084 VNPEAVTTMTTRTKPSTRTTSFPTVTTTAVPTNTTIKSNPTSTPTVPRTTT 4134
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 98.6 bits (244), Expect = 4e-20
Identities = 207/776 (26%), Positives = 266/776 (34%), Gaps = 122/776 (15%)
Query: 680 SAMTPPLPLQDTDLS-SAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPK 738
S T P PL L SA + VA L+ + P P P
Sbjct: 121 SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTP-------GTPS 173
Query: 739 PVAAATLVSQQAEEGLTLPQDSAMT-PPLPLQDTDLSSA-------PKPVAAATIVSQQA 790
P A + E GL P SA PP +SSA P P A A
Sbjct: 174 PAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRR---PSA 230
Query: 791 EEGLTLPQD---SAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPL- 846
GL P S+ PL SA A SQ +GL + +TPP
Sbjct: 231 GGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRK 290
Query: 847 -------PLQDTDLSS----------APKPVAAATPVSQQAEEGLTLPQDSAMTPPLPLQ 889
PL + L++ P P AATP+ TLP + PLPL
Sbjct: 291 DAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPA------TLPPSPPLATPLPLA 344
Query: 890 DTDLSSAPK----PVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATP 945
S+ P P ATP SQ A +T P M AP LQ P P L T
Sbjct: 345 PPSPSAPPSLQTLPSPPATPPSQ-APPSMTTPP---MQAPPSLQTIPPIQVPHSL---TS 397
Query: 946 QTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQP 1005
+LQA P+A + Q +LG P + ++ L P Q Q P
Sbjct: 398 PSLQAPPS------PLALSSLQAT-TSLGS-PTLQATHSFLTMSPR-----QTQASLTSP 444
Query: 1006 AAEAGTPWAAQEDADSTLGMEALSLPE--PASGAGEEIAEALSRPGREACLEARAHTGDG 1063
+ A TP DS LSLP P + LS P L+A +
Sbjct: 445 SRPASTP------PDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASH 498
Query: 1064 AKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALGGARE-VPD---------APPAACPE 1113
+ P +P + + + L P + + P S E +P + P P
Sbjct: 499 S-PQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPH 557
Query: 1114 VSQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAP-A 1172
+ +P + S +TP P PS++AT P++ S +G P P +
Sbjct: 558 LETPPCPAPCPLQAPPSPLTTPPPETPSSIATPP-----PQAPPALASPPLQGLPSPPLS 612
Query: 1173 PTSAPTSQQPEPVLGLGSVEQPHEVP-----SVLGTPLLQPPENLAKGQPSTPVDRPLGP 1227
P + P Q P P L L ++ P P S L TP Q P LA P P P
Sbjct: 613 PLATPPPQAP-PXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP 671
Query: 1228 DPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSL-GLPPPQAGVQPAAAAVSG 1286
AP + PP PP P + PP + PP + P+A
Sbjct: 672 PVQAPFS------PPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 725
Query: 1287 TTQPLGTGP-RVSLS-PHSPLLSPKVASMDAKDLALQILPPCQV---PPPSGPQSPAGPQ 1341
PL P +V S P SP +SP A+ + L PP QV PP S P SP
Sbjct: 726 APPPLAAPPLQVPPSPPASPPMSPS-ATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKP 784
Query: 1342 GLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELDEQDILAPQTVQCPAQAP 1397
AP SP A GQ S SA L + P P QAP
Sbjct: 785 PPQAPPALATPPLQALPSPPASFPGQAPFS---PSASLPMSPLATP-----PPQAP 832
Score = 94.0 bits (232), Expect = 1e-18
Identities = 247/1012 (24%), Positives = 345/1012 (34%), Gaps = 181/1012 (17%)
Query: 498 VATRVTPQAGEEETDSTAGQESAAMAMP-QPSQEGISEILGQESVTAEKLPTPQEETSLT 556
+++ TP + + +A A A P QP +G+ +++ ++ P+++ +
Sbjct: 242 LSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGL------QALRPPQVTPPRKDAAPA 295
Query: 557 LCPDSPQNLKEEGGLDLPSGRK------PVAAATIVPRQAKEDLTLPQDSAMTPPLPLQD 610
L P S L PSG K P AAT +P TLP + PLPL
Sbjct: 296 LGPLSSSPLATPS----PSGTKARPVPPPDNAATPLPA------TLPPSPPLATPLPLAP 345
Query: 611 TDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQA 670
S+ P + T+ S A P S+ TPP+ P + T+ Q
Sbjct: 346 PSPSAPP---SLQTLPSPPATPPSQAPP-SMTTPPMQA----------PPSLQTIPPIQV 391
Query: 671 EEGLTLPQDSAMTPPLPLQDTDL---SSAPKPVAAAT-----LVSQQAEEGLTLPQDSAM 722
LT P S PP PL + L +S P AT + +Q + LT P A
Sbjct: 392 PHSLTSP--SLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPAS 449
Query: 723 TPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPL---PLQDTDLSSAPKP 779
TPP +P A +L + + P S ++ PL PLQ ++ P
Sbjct: 450 TPP---------DSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSP 500
Query: 780 VAA-ATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQ 838
A ++++ E +L S TPP L L + P + A Q A LT P
Sbjct: 501 QAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLP---SLAPPPLQTASAPLTTPH 557
Query: 839 DSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPK 898
TPP P L + P P+ P + + P A P L L P
Sbjct: 558 --LETPPCPAP-CPLQAPPSPLTTPPP---ETPSSIATPPPQA---PPALASPPLQGLPS 608
Query: 899 PVAA--ATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAP 956
P + ATP QA L LP A +P P + P P A P L AP
Sbjct: 609 PPLSPLATP-PPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQA---PNALAVHLLQAP 664
Query: 957 GTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPA-ALDQVQQDDPQPAAEAGTPWAA 1015
+ P + Q P +P +A P+ P+ A +Q PA+ +P A
Sbjct: 665 FSPPPSPPVQAPFSPPASPPVSP---SATPPSQAPPSLAAPPLQVPPSPPASPPMSPSAT 721
Query: 1016 QE-DADSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETL 1074
A L L +P P+ A ++ + + P R L A A P L
Sbjct: 722 PPPQAPPPLAAPPLQVP-PSPPASPPMSPSATPPPRVPPLLA-------APP-------L 766
Query: 1075 EVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERG------ 1128
+V L P S L A+ P APPA QA L SP G
Sbjct: 767 QVPPSPPASL--------PMSPL--AKPPPQAPPALATPPLQA-LPSPPASFPGQAPFSP 815
Query: 1129 -----LSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPE 1183
+S +TP P P +A A L P S +S P P PT P +
Sbjct: 816 SASLPMSPLATPPPQAPPVLA--APLLQVPPSPP---ASPTLQAPRRP-PTPGPDTSVSG 869
Query: 1184 PVLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPL 1243
P L L P PS + L P+ +T L S P A A+ PP
Sbjct: 870 PRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPD 929
Query: 1244 EPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHS 1303
A C PAA + G PL +P +
Sbjct: 930 AELAAC----------------------------HPAAWS-RGPAPPLA----FRGAPGA 956
Query: 1304 PLLSPKVASMDAKDLALQILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSPRAL 1363
PL P + D C + GP+S G P A
Sbjct: 957 PLPWPPATGPGSAD------GLCTIYETEGPESATPAPGALDPGPSPGTSG----GKAAA 1006
Query: 1364 GSGQHSDSHGESSAELDE-----------QDILAPQTVQCPAQAPAGGSEETIAKAKQSR 1412
G+G + S A L E Q +L+ + A+ AGGS A+
Sbjct: 1007 GAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGG 1066
Query: 1413 SEKKARKAMSKLGLRQIQGVTRITIQKSKNILFVIA-KPDVFKSPASDTYVV 1463
AR A+S L + + + +I V + PD SP D VV
Sbjct: 1067 VTGGARAALSDAELGRWAELLSPLDESRASITSVTSFSPDDVASPQGDWTVV 1118
Score = 93.2 bits (230), Expect = 2e-18
Identities = 205/819 (25%), Positives = 273/819 (33%), Gaps = 135/819 (16%)
Query: 480 TATVTPHTLQVAP-GLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQ 538
T H Q P GLQ +VTP ++ + S+ +A P PS +
Sbjct: 262 TPRAPAHPSQPKPKGLQALRPPQVTPPR-KDAAPALGPLSSSPLATPSPSGTKARPVPPP 320
Query: 539 ESVT----AEKLPTPQEETSLTLCPDSP------QNL---------KEEGGLDLPSGRKP 579
++ A P+P T L L P SP Q L + + P + P
Sbjct: 321 DNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAP 380
Query: 580 VAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDL---SSAPKPVAAAT-----IVSQQAE 631
+ TI P Q LT P S PP PL + L +S P AT + +Q +
Sbjct: 381 PSLQTIPPIQVPHSLTSP--SLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQ 438
Query: 632 EGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPL---PL 688
LT P TPP +P A +L + + P S ++ PL PL
Sbjct: 439 ASLTSPSRPASTPP---------DSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPL 489
Query: 689 QDTDLSSAPKPVAA-ATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVS 747
Q ++ P A ++L+ E +L S TPP L L + P + A
Sbjct: 490 QALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLP---SLAPPPL 546
Query: 748 QQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLP 807
Q A LT P TPP P L + P P+ T + + P A P
Sbjct: 547 QTASAPLTTPH--LETPPCPAP-CPLQAPPSPL---TTPPPETPSSIATPPPQA---PPA 597
Query: 808 LQDTDLSSAPKP-VAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPV 866
L L P P ++ QA L LP A PP P LS P+A +P
Sbjct: 598 LASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQA--PPSPPASPPLS----PLATPSPQ 651
Query: 867 SQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPL 926
+ A L + P P+Q A PV+ + QA L P +P
Sbjct: 652 APNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP 711
Query: 927 PLQDTGPTSGPEPLA----VATPQTLQAEAGCAPGTEPVATMAQQEVG-EALGPRPAPEE 981
P++ P P A A P + +P P AT + A P P
Sbjct: 712 ASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPS 771
Query: 982 KNAALP----TVPEPAALDQVQQDDPQ--PAAEAGTPWAAQEDADSTLGMEALSLPEPAS 1035
A+LP P P A + Q P+ A P A ++L M L+ P P
Sbjct: 772 PPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPP-- 829
Query: 1036 GAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRS 1095
+ L+ P + P P TL+ + P GPR
Sbjct: 830 ----QAPPVLAAPLLQ------------VPPSPPASPTLQAPRRPPTP-GPDTSVSGPRL 872
Query: 1096 ALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPES 1155
L A P PP+ P + L P S STPE DS PE
Sbjct: 873 TLALA-PGPPPPPSRSP---SSTLSGPDLAGHSSSATSTPEEL--------RGYDSGPEG 920
Query: 1156 SVGAVSSLDRGCPDAPAPTSAPT--SQQPEPVLGLGSVEQPHEVPSVLGTPLLQPP---E 1210
A PDA P S+ P P L G PL PP
Sbjct: 921 GAAASPP-----PDAELAACHPAAWSRGPAPPLAFRGAP---------GAPLPWPPATGP 966
Query: 1211 NLAKG----------QPSTPVDRPLGPDPSAPGTLAGAA 1239
A G + +TP L P PS PGT G A
Sbjct: 967 GSADGLCTIYETEGPESATPAPGALDPGPS-PGTSGGKA 1004
Score = 61.2 bits (147), Expect = 7e-09
Identities = 135/546 (24%), Positives = 178/546 (32%), Gaps = 55/546 (10%)
Query: 949 QAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAE 1008
+A+AG A T PRP P AAL + A+ + +
Sbjct: 7 KAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIG 66
Query: 1009 AGT-----PWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDG 1063
T P A + T S P PASG GE A + RA
Sbjct: 67 GATIPESAPRAGPTRSAGTSSRNPASRP-PASGRGERAPPAKNTSPGPVSSPGRA--SGT 123
Query: 1064 AKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALG-GAREVPDAPPAACPEVSQARLLSP 1122
+P ++ L + + +E + A E RSAL GAR P P + AR
Sbjct: 124 TRPGPLGQKGLRI-SAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRA 182
Query: 1123 AREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDA------PA---- 1172
A E GL + P S+ S E S S R P A PA
Sbjct: 183 AGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL 242
Query: 1173 -----PTSAPTSQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDRPLGP 1227
P S+P P G P G L+PP+ + + P PL
Sbjct: 243 SSSATPLSSPARSGPS-ARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSS 301
Query: 1228 DPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAA-AAVSG 1286
P A + +G P+ PP P + PP L P P A P+A ++
Sbjct: 302 SPLATPSPSGTKARPVPPPDNAATPLP---ATLPPSPP--LATPLPLAPPSPSAPPSLQT 356
Query: 1287 TTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLALQILPPCQVP---PPSGPQSPAGPQGL 1343
P T P S +P S P A +LQ +PP QVP Q+P P L
Sbjct: 357 LPSPPATPP--SQAPPSMTTPPMQAPP-----SLQTIPPIQVPHSLTSPSLQAPPSPLAL 409
Query: 1344 S---------APEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELDEQDILAPQTVQCPA 1394
S +P Q L SPR + S S +S D + AP + PA
Sbjct: 410 SSLQATTSLGSPTLQATHSFLTM-SPRQTQASLTSPSR-PASTPPDSPPLQAP--LSLPA 465
Query: 1395 QAPAGGSEETIAKAKQSRSEKKARKAMSKLGLRQIQGVTRITIQKSKNILFVIAKPDVFK 1454
P S S +A+S L Q I +A P +
Sbjct: 466 SPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQT 525
Query: 1455 SPASDT 1460
PAS T
Sbjct: 526 PPASLT 531
Score = 37.4 bits (85), Expect = 0.11
Identities = 65/279 (23%), Positives = 87/279 (31%), Gaps = 45/279 (16%)
Query: 80 PSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIVMGEETCQALLSPRAARTAL 139
PS P + +P+ P L + PL A P ET ++ +P
Sbjct: 539 PSLAPPPLQTASAPLTTPH-LETPPCPAPCPLQAPPSPLTTPPPETPSSIATP------- 590
Query: 140 RDQEGGHASPDPPPELCSQGDLSVPSPP------PDPDS--------FFTPPSTPTKTTY 185
P PP L S +PSPP P P + PPS P
Sbjct: 591 --------PPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASP-- 640
Query: 186 ALLPACGPHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLAPAEGL 245
L P P A ++ A + SPP SP + S SPS + AP
Sbjct: 641 PLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLA 700
Query: 246 DFPSGWGLSPQGSMVDERELHPAGTPEPPSSESSLSADSSSSWGQEGHFFDLDFLANDPM 305
P SP S P PP + L S A+ PM
Sbjct: 701 APPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPP-------------ASPPM 747
Query: 306 IPAALLPFQGSLIFQVEAVEVTPLSPEEEEEEAVADPDP 344
P+A P + + ++V P P +A P P
Sbjct: 748 SPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPP 786
Score = 33.9 bits (76), Expect = 1.3
Identities = 76/309 (24%), Positives = 105/309 (33%), Gaps = 72/309 (23%)
Query: 13 PEADRPGPRTDLSCDAAAATT----------ILGGDRREPCA------LTP-------GP 49
P GPR +S + +TT GG + P + TP GP
Sbjct: 198 PRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGP 257
Query: 50 SHLALTFLPSKPGARPQPEGASWDAGPGGAPSAWADPGEGGP---SPMLLPEGLSSQAL- 105
S P+ P ++P+P+G P P GP SP+ P ++A
Sbjct: 258 SARGTPRAPAHP-SQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARP 316
Query: 106 -----STEAPLPATLEPRIVMGEETCQALLSPRAARTALRDQEGGHASPDPPPELCSQGD 160
+ PLPATL P + T L P SP PP L Q
Sbjct: 317 VPPPDNAATPLPATLPPSPPLA--TPLPLAPP---------------SPSAPPSL--QTL 357
Query: 161 LSVPSPPPD--PDSFFTPPSTPTKTTYALLPACGPHGDARDSEAELRDELLDSPPASPSG 218
S P+ PP P S TPP + + P PH L L +PP+ +
Sbjct: 358 PSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPH--------SLTSPSLQAPPSPLAL 409
Query: 219 SYITADGDSWASSPSCSLSLLAPA-----EGLDFPSGWGLSPQGSMVDERELH-PAGTPE 272
S + A + + + S L + L PS P + D L P P
Sbjct: 410 SSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPS----RPASTPPDSPPLQAPLSLPA 465
Query: 273 PPSSESSLS 281
P ++SLS
Sbjct: 466 SPPLQTSLS 474
>gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]
Length = 2089
Score = 98.2 bits (243), Expect = 5e-20
Identities = 235/1049 (22%), Positives = 366/1049 (34%), Gaps = 140/1049 (13%)
Query: 401 DERLYSG-EPHAQATLLQDSVQKTEEESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLS 459
+E L G + Q LL Q+ E + G + + ++ +E + + ++
Sbjct: 849 EEELTKGKQDREQKQLLARDTQRQESDKNGESASPERDRESLKVEIETSEEIQEKQV--- 905
Query: 460 QRQELISEVTEEGLALGQESTATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQES 519
Q+Q L S+ E + + + P + +E T Q GE E S +
Sbjct: 906 QKQTLPSKAFEREVERPVANRECDPAELEEKVPKVILERDT----QRGEPEGGSQDQKGQ 961
Query: 520 AAMAMPQPSQEGISEILGQESVTAEKLPTPQ-EETSLTLCPDSPQNLKEEGGLD--LPSG 576
A+ P+P G ++ G S P P ++ P SP+ ++G L+ +P
Sbjct: 962 ASSPTPEPGV-GAGDLPGPTSA-----PVPSGSQSGGRGSPVSPRR-HQKGLLNCKMPPA 1014
Query: 577 RKP--VAAATIVPR--QAKEDLTLPQDSAMTPPLPLQDTDLSS----APKPVAAATIVSQ 628
K + AA V R Q D LP P P + + S AP P+ + + S
Sbjct: 1015 EKASRIRAAEKVSRGDQESPDACLPPTVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSI 1074
Query: 629 QAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPL 688
+ T S P PL PKP + ++++ P SA P P
Sbjct: 1075 KPTVRKTRQDGSQEAPEAPLSSELEPFHPKP----KIRTRKSSRMTPFPATSAAPEPHPS 1130
Query: 689 QDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPP--LPLQDTDLSSAPKPVAAATLV 746
T PKP + AT S+ + P+ T P P TD +P + T
Sbjct: 1131 TSTAQPVTPKPTSQATR-SRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTR- 1188
Query: 747 SQQAEEGLTLPQDSAMTPP--LPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTP 804
+++ + P+ T P TD +P + AT ++ + P+ T
Sbjct: 1189 GRKSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATR-GRKNRSSVKTPEPVVPTA 1247
Query: 805 P--LPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPP--LPLQDTDLSSAPKPV 860
P P TD +P AT ++ + P+ T P P TD PKP
Sbjct: 1248 PELQPSTSTDQPVTSEPTYQATR-GRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPT 1306
Query: 861 AAATPVSQQAEEGLTLPQDSAMTPPLPLQ---DTDLSSAPKPVAAATPVSQQAEEGLTLP 917
+ T S+ + P+ T P LQ TD PKP + T S+ + P
Sbjct: 1307 SRTTR-SRTNMSSVKTPETVVPTAP-ELQISTSTDQPVTPKPTSRTTR-SRTNMSSVKNP 1363
Query: 918 QDSAMTAPL--PLQDTGPTSGPEPLAVATPQTLQAEAGCAPGT---------------EP 960
+ + AP P T PEP + AT +G P T +P
Sbjct: 1364 ESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPETLVPTAPKLEPSTSTDQP 1423
Query: 961 VATMAQQEVGEALGPRPAPEEKNAALPTVPE---PAALDQVQQDDPQPAAEAGTPWAAQE 1017
V + R + + +PT PE + DQ +P A G +
Sbjct: 1424 VTPEPTSQATRGRTNRSSVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSSV 1483
Query: 1018 DADSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVE 1077
T+ A L AS +E SR R + T + P +P+ +
Sbjct: 1484 KTPETVVPTAPELQASASTDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPELQPSTST 1543
Query: 1078 NQQEGGLKPLAQEHGPRSALGGARE---------VPDAPPAACPEVSQARLLSPAREERG 1128
+Q P+ E R+ G VP AP P S+ +L++P R
Sbjct: 1544 DQ------PVTPEPTSRATRGRTNRSSVKTPESIVPIAPELQ-PSTSRNQLVTPEPTSRA 1596
Query: 1129 L------SGKSTPEPTLPSAV----ATEASLDSCPESSVGAV------SSLDRGCPDAPA 1172
S TPEP +P+A T P+ + A SS+ P PA
Sbjct: 1597 TRCRTNRSSVKTPEPVVPTAPEPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPA 1656
Query: 1173 PTS----APTSQQPEP-VLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDRPLGP 1227
+ PT Q P + G + +V P+ PE Q D+P+ P
Sbjct: 1657 ASDLEPFTPTDQSVTPEAIAQGGQSKTLRSSTVRAMPVPTTPEF----QSPVTTDQPISP 1712
Query: 1228 DPSA-------------PGTLAGA-----ALPPLEPPAPCLCQDPQEDSVEDEEPPGSLG 1269
+P PG+LA PLEP + ++ + +V E ++
Sbjct: 1713 EPITQPSCIKRQRAAGNPGSLAAPIDHKPCSAPLEPKSQA-SRNQRWGAVRAAESLTAIP 1771
Query: 1270 LPP-PQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLALQILPPCQV 1328
P PQ P A+ +P G S +P L PK + + LA PP Q
Sbjct: 1772 EPASPQLLETPIHASQIQKVEPAGR------SRFTPELQPKASQSRKRSLATMDSPPHQK 1825
Query: 1329 PPPSGPQSPAGPQGLSAPEQQEDEDSLEE 1357
P G S + ++E+ED+ E+
Sbjct: 1826 QPQRGEVSQK-----TVIIKEEEEDTAEK 1849
Score = 73.6 bits (179), Expect = 1e-12
Identities = 186/864 (21%), Positives = 296/864 (34%), Gaps = 102/864 (11%)
Query: 487 TLQVAPGLQVEVATRVTPQAG--EEETDSTAGQESAAMAMPQPSQEGISEILGQESVTAE 544
T+ G+ E A RV P+ G E ET+ + + + +G + ++ + +
Sbjct: 809 TVDKVMGIPKETAERVGPERGPLERETEKLLPERQTDVTGEEELTKGKQDREQKQLLARD 868
Query: 545 KLPTPQEETSLTLCPDSP-QNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMT 603
++ + P+ ++LK E K V T+ + + ++ P +
Sbjct: 869 TQRQESDKNGESASPERDRESLKVEIETSEEIQEKQVQKQTLPSKAFEREVERPVANREC 928
Query: 604 PPLPLQDTDLSSAPKPVAAATIVSQQAE-EGLTLPQDSVMTPPLPLQDTELSSAPKPVAA 662
P L++ PK + +Q+ E EG + Q + P P P P +A
Sbjct: 929 DPAELEE----KVPKVILERD--TQRGEPEGGSQDQKGQASSPTPEPGVGAGDLPGPTSA 982
Query: 663 ATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKP--VAAATLVSQQAEEG--LTLPQ 718
V ++ G S L + + A K + AA VS+ +E LP
Sbjct: 983 P--VPSGSQSGGRGSPVSPRRHQKGLLNCKMPPAEKASRIRAAEKVSRGDQESPDACLPP 1040
Query: 719 DSAMTPPLPLQDTDLSS----APKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLS 774
P P + + S AP P+ + L S + T S P PL
Sbjct: 1041 TVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRKTRQDGSQEAPEAPLSSELEP 1100
Query: 775 SAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGL 834
PKP I ++++ P SA P P T PKP + AT S+ +
Sbjct: 1101 FHPKP----KIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQATR-SRTNRSSV 1155
Query: 835 TLPQDSAMTPP--LPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTPP--LPLQD 890
P+ T P P TD +P + T +++ + P+ T P
Sbjct: 1156 KTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTR-GRKSRSSVKTPETVVPTALELQPSTS 1214
Query: 891 TDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQA 950
TD +P + AT ++ + P+ TAP LQ + T P V + T QA
Sbjct: 1215 TDRPVTSEPTSQATR-GRKNRSSVKTPEPVVPTAP-ELQPSTSTDQP----VTSEPTYQA 1268
Query: 951 EAG-----CAPGTEPVATMAQQ-----EVGEALGPRPAPEEKNA------------ALPT 988
G EPV A + + P+P + +PT
Sbjct: 1269 TRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVKTPETVVPT 1328
Query: 989 VPEPAALDQVQQD-DPQPAAE---AGTPWAAQEDADSTLGMEALSLPEPASGAGEEIAEA 1044
PE Q P+P + + T ++ ++ +ST+ + A LP S E
Sbjct: 1329 APELQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPI-APELPPSTSTEQPVTPEP 1387
Query: 1045 LSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALGGAREVP 1104
SR R + T + P +P+ E Q +P +Q R+ +
Sbjct: 1388 TSRATRGRKNRSSGKTPETLVPTAPKLEP-STSTDQPVTPEPTSQATRGRTNRSSVKTPE 1446
Query: 1105 DAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVA-TEASLDSCPESSVGAVSSL 1163
P A PE+ + TPEPT + T+ S PE+ V L
Sbjct: 1447 TVVPTA-PELQPST---------STDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPEL 1496
Query: 1164 DRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDR 1223
TS PTS+ SV+ P V V P LQP ST D+
Sbjct: 1497 QASASTDQPVTSEPTSRTTRGRKNRSSVKTPETV--VPAAPELQP---------STSTDQ 1545
Query: 1224 PLGPDPSAPGTLAGAALPPLEPP------APCLCQDPQEDSVEDEEPP----------GS 1267
P+ P+P++ T ++ P AP L + + EP S
Sbjct: 1546 PVTPEPTSRATRGRTNRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATRCRTNRSS 1605
Query: 1268 LGLPPPQAGVQPAAAAVSGTTQPL 1291
+ P P P + T QP+
Sbjct: 1606 VKTPEPVVPTAPEPHPTTSTDQPV 1629
Score = 47.0 bits (110), Expect = 1e-04
Identities = 113/538 (21%), Positives = 181/538 (33%), Gaps = 87/538 (16%)
Query: 858 KPVAAATPVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAE-EGLTL 916
K V T S+ E + P + P L++ PK + +Q+ E EG +
Sbjct: 903 KQVQKQTLPSKAFEREVERPVANRECDPAELEE----KVPKVILERD--TQRGEPEGGSQ 956
Query: 917 PQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPVATMAQQEVGEALGPR 976
Q ++P P G P P + P Q+ +P V+ Q+ L +
Sbjct: 957 DQKGQASSPTPEPGVGAGDLPGPTSAPVPSGSQSGGRGSP----VSPRRHQK--GLLNCK 1010
Query: 977 PAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPASG 1036
P EK + + + + DQ D P P Q+ +S + L+ P S
Sbjct: 1011 MPPAEKASRIRAAEKVSRGDQESPDACLPPTVPEAPAPPQKPLNSQ-SQKHLAPPPLLSP 1069
Query: 1037 AGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSA 1096
I + + ++ EA P++P LE P + +S+
Sbjct: 1070 LLPSIKPTVRKTRQDGSQEA---------PEAPLSSELEP-------FHPKPKIRTRKSS 1113
Query: 1097 LGGAREVPDAPPAACPEVSQARLLSP------AREERGLSGKSTPEPTLPSAVATEASLD 1150
A P P S A+ ++P R S TPEP +P+A + S
Sbjct: 1114 RMTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVPTAPELQPSTS 1173
Query: 1151 SCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEV-PSVLGTPLLQPP 1209
+ D P TS PTSQ SV+ P V P+ L
Sbjct: 1174 T-----------------DQPV-TSEPTSQVTRGRKSRSSVKTPETVVPTALEL------ 1209
Query: 1210 ENLAKGQPSTPVDRPLGPDPSAPGT-----LAGAALP-PLEPPAPCLCQDPQEDSVEDEE 1263
QPST DRP+ +P++ T + P P+ P AP L D E
Sbjct: 1210 ------QPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPVTSE 1263
Query: 1264 PP----------GSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRV----SLSPHSPLLSPK 1309
P S+ P P P + T +P+ P S + S + +P+
Sbjct: 1264 PTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVKTPE 1323
Query: 1310 VASMDAKDLALQILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQ 1367
A +L + V P ++ +S+ + E + + P + + Q
Sbjct: 1324 TVVPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQ 1381
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 94.7 bits (234), Expect = 6e-19
Identities = 205/931 (22%), Positives = 322/931 (34%), Gaps = 135/931 (14%)
Query: 468 VTEEGLALGQESTATVTPHTL-----QVAPGLQVEVATRVTPQAG-------EEETDSTA 515
V E G L TP T +V+ ++ A + P+ +ET T
Sbjct: 85 VDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTV 144
Query: 516 GQESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLT-LCPDSPQNLKEEGGLDLP 574
+E+ + + G+E T+ K E+TS L P S K +
Sbjct: 145 NKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETT 204
Query: 575 SGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPK-PVAAATIVSQQAEEG 633
+ A P++ T P++ A T P T + SAP P A ++ A
Sbjct: 205 TK----GPALTTPKEPTP--TTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTT 258
Query: 634 LTLPQDSVMTPPLPLQDTE----LSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQ 689
P + P P E + P P + + E T P+ A T P
Sbjct: 259 PKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA 318
Query: 690 DTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPL-PLQDTDLSSAPK-PVAAATLVS 747
T P P E T P++ A T P P T AP P A +
Sbjct: 319 PTT-PKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTT 377
Query: 748 QQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQA------EEGLTLPQDSA 801
+ E T P++ A T T AP +A ++ E T P++ A
Sbjct: 378 K--EPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPA 435
Query: 802 -MTPPLPLQDTDLSSAP----KPVAAAT---IVSQQAEEGLTLPQDSAMTPPLPLQDTDL 853
TP P T AP +P T + E T P+++A T P L T
Sbjct: 436 PTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPT-- 493
Query: 854 SSAPKPVAAATPVSQQAEEGLTLPQDSA-MTPPLPLQDTDLSSAPKPVAAATPVSQQAEE 912
P+ +A TP + T P++ A TP P T AP AA P + E
Sbjct: 494 --TPEKLAPTTP----EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAP-NTPKEP 546
Query: 913 GLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGT--EPVATMAQQEVG 970
T P++ A T P ++ PT+ P+ A TP+ G AP T EP T ++
Sbjct: 547 APTTPKEPAPTTP---KEPAPTT-PKETAPTTPK------GTAPTTLKEPAPTTPKKPAP 596
Query: 971 EALGP------------RPAPEEKNAALPTVP-EPAALDQVQQDDPQPAAEAGT-PWAAQ 1016
+ L P +PAP PT P EPA +P P GT P +
Sbjct: 597 KELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA---PTTPKEPAPTTPKGTAPTTLK 653
Query: 1017 EDA--------------DSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGD 1062
E A +T G + + +PA +E A + + A T
Sbjct: 654 EPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTP 713
Query: 1063 GAKPDSPQ--------KETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEV 1114
P + KE + + L+ E P+ AL + + P P P
Sbjct: 714 ETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPK-ALENSPKEPGVPTTKTPAA 772
Query: 1115 SQARLLSPARE---ERGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAP 1171
++ + + A++ ER L ++TPE T + T+ + + +++ +++
Sbjct: 773 TKPEMTTTAKDKTTERDL--RTTPETTTAAPKMTKETATTTEKTTESKITA-------TT 823
Query: 1172 APTSAPTSQQPEP--VLGLGSVEQPHEV----PSVLGTPLLQPPENLAKGQPSTPVDRPL 1225
++ T+Q P + L + +V ++ T ++ PE AK + +
Sbjct: 824 TQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKAT 883
Query: 1226 GPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAAAAVS 1285
P P P P P + P+ ++ P + P P S
Sbjct: 884 TPKPQK---------PTKAPKKPTSTKKPK--TMPRVRKPKTTPTPRKMTSTMPELNPTS 932
Query: 1286 GTTQP-LGTGPRVSLSPHSPLLSPKVASMDA 1315
+ L T R + +P+S L+ S DA
Sbjct: 933 RIAEAMLQTTTRPNQTPNSKLVEVNPKSEDA 963
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 94.7 bits (234), Expect = 6e-19
Identities = 205/931 (22%), Positives = 322/931 (34%), Gaps = 135/931 (14%)
Query: 468 VTEEGLALGQESTATVTPHTL-----QVAPGLQVEVATRVTPQAG-------EEETDSTA 515
V E G L TP T +V+ ++ A + P+ +ET T
Sbjct: 126 VDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTV 185
Query: 516 GQESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLT-LCPDSPQNLKEEGGLDLP 574
+E+ + + G+E T+ K E+TS L P S K +
Sbjct: 186 NKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETT 245
Query: 575 SGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPK-PVAAATIVSQQAEEG 633
+ A P++ T P++ A T P T + SAP P A ++ A
Sbjct: 246 TK----GPALTTPKEPTP--TTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTT 299
Query: 634 LTLPQDSVMTPPLPLQDTE----LSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQ 689
P + P P E + P P + + E T P+ A T P
Sbjct: 300 PKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA 359
Query: 690 DTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPL-PLQDTDLSSAPK-PVAAATLVS 747
T P P E T P++ A T P P T AP P A +
Sbjct: 360 PTT-PKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTT 418
Query: 748 QQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQA------EEGLTLPQDSA 801
+ E T P++ A T T AP +A ++ E T P++ A
Sbjct: 419 K--EPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPA 476
Query: 802 -MTPPLPLQDTDLSSAP----KPVAAAT---IVSQQAEEGLTLPQDSAMTPPLPLQDTDL 853
TP P T AP +P T + E T P+++A T P L T
Sbjct: 477 PTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPT-- 534
Query: 854 SSAPKPVAAATPVSQQAEEGLTLPQDSA-MTPPLPLQDTDLSSAPKPVAAATPVSQQAEE 912
P+ +A TP + T P++ A TP P T AP AA P + E
Sbjct: 535 --TPEKLAPTTP----EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAP-NTPKEP 587
Query: 913 GLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGT--EPVATMAQQEVG 970
T P++ A T P ++ PT+ P+ A TP+ G AP T EP T ++
Sbjct: 588 APTTPKEPAPTTP---KEPAPTT-PKETAPTTPK------GTAPTTLKEPAPTTPKKPAP 637
Query: 971 EALGP------------RPAPEEKNAALPTVP-EPAALDQVQQDDPQPAAEAGT-PWAAQ 1016
+ L P +PAP PT P EPA +P P GT P +
Sbjct: 638 KELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA---PTTPKEPAPTTPKGTAPTTLK 694
Query: 1017 EDA--------------DSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGD 1062
E A +T G + + +PA +E A + + A T
Sbjct: 695 EPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTP 754
Query: 1063 GAKPDSPQ--------KETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEV 1114
P + KE + + L+ E P+ AL + + P P P
Sbjct: 755 ETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPK-ALENSPKEPGVPTTKTPAA 813
Query: 1115 SQARLLSPARE---ERGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAP 1171
++ + + A++ ER L ++TPE T + T+ + + +++ +++
Sbjct: 814 TKPEMTTTAKDKTTERDL--RTTPETTTAAPKMTKETATTTEKTTESKITA-------TT 864
Query: 1172 APTSAPTSQQPEP--VLGLGSVEQPHEV----PSVLGTPLLQPPENLAKGQPSTPVDRPL 1225
++ T+Q P + L + +V ++ T ++ PE AK + +
Sbjct: 865 TQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKAT 924
Query: 1226 GPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAAAAVS 1285
P P P P P + P+ ++ P + P P S
Sbjct: 925 TPKPQK---------PTKAPKKPTSTKKPK--TMPRVRKPKTTPTPRKMTSTMPELNPTS 973
Query: 1286 GTTQP-LGTGPRVSLSPHSPLLSPKVASMDA 1315
+ L T R + +P+S L+ S DA
Sbjct: 974 RIAEAMLQTTTRPNQTPNSKLVEVNPKSEDA 1004
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 94.7 bits (234), Expect = 6e-19
Identities = 205/931 (22%), Positives = 322/931 (34%), Gaps = 135/931 (14%)
Query: 468 VTEEGLALGQESTATVTPHTL-----QVAPGLQVEVATRVTPQAG-------EEETDSTA 515
V E G L TP T +V+ ++ A + P+ +ET T
Sbjct: 178 VDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTV 237
Query: 516 GQESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLT-LCPDSPQNLKEEGGLDLP 574
+E+ + + G+E T+ K E+TS L P S K +
Sbjct: 238 NKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETT 297
Query: 575 SGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPK-PVAAATIVSQQAEEG 633
+ A P++ T P++ A T P T + SAP P A ++ A
Sbjct: 298 TK----GPALTTPKEPTP--TTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTT 351
Query: 634 LTLPQDSVMTPPLPLQDTE----LSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQ 689
P + P P E + P P + + E T P+ A T P
Sbjct: 352 PKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA 411
Query: 690 DTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPL-PLQDTDLSSAPK-PVAAATLVS 747
T P P E T P++ A T P P T AP P A +
Sbjct: 412 PTT-PKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTT 470
Query: 748 QQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQA------EEGLTLPQDSA 801
+ E T P++ A T T AP +A ++ E T P++ A
Sbjct: 471 K--EPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPA 528
Query: 802 -MTPPLPLQDTDLSSAP----KPVAAAT---IVSQQAEEGLTLPQDSAMTPPLPLQDTDL 853
TP P T AP +P T + E T P+++A T P L T
Sbjct: 529 PTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPT-- 586
Query: 854 SSAPKPVAAATPVSQQAEEGLTLPQDSA-MTPPLPLQDTDLSSAPKPVAAATPVSQQAEE 912
P+ +A TP + T P++ A TP P T AP AA P + E
Sbjct: 587 --TPEKLAPTTP----EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAP-NTPKEP 639
Query: 913 GLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGT--EPVATMAQQEVG 970
T P++ A T P ++ PT+ P+ A TP+ G AP T EP T ++
Sbjct: 640 APTTPKEPAPTTP---KEPAPTT-PKETAPTTPK------GTAPTTLKEPAPTTPKKPAP 689
Query: 971 EALGP------------RPAPEEKNAALPTVP-EPAALDQVQQDDPQPAAEAGT-PWAAQ 1016
+ L P +PAP PT P EPA +P P GT P +
Sbjct: 690 KELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA---PTTPKEPAPTTPKGTAPTTLK 746
Query: 1017 EDA--------------DSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGD 1062
E A +T G + + +PA +E A + + A T
Sbjct: 747 EPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTP 806
Query: 1063 GAKPDSPQ--------KETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEV 1114
P + KE + + L+ E P+ AL + + P P P
Sbjct: 807 ETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPK-ALENSPKEPGVPTTKTPAA 865
Query: 1115 SQARLLSPARE---ERGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAP 1171
++ + + A++ ER L ++TPE T + T+ + + +++ +++
Sbjct: 866 TKPEMTTTAKDKTTERDL--RTTPETTTAAPKMTKETATTTEKTTESKITA-------TT 916
Query: 1172 APTSAPTSQQPEP--VLGLGSVEQPHEV----PSVLGTPLLQPPENLAKGQPSTPVDRPL 1225
++ T+Q P + L + +V ++ T ++ PE AK + +
Sbjct: 917 TQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKAT 976
Query: 1226 GPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAAAAVS 1285
P P P P P + P+ ++ P + P P S
Sbjct: 977 TPKPQK---------PTKAPKKPTSTKKPK--TMPRVRKPKTTPTPRKMTSTMPELNPTS 1025
Query: 1286 GTTQP-LGTGPRVSLSPHSPLLSPKVASMDA 1315
+ L T R + +P+S L+ S DA
Sbjct: 1026 RIAEAMLQTTTRPNQTPNSKLVEVNPKSEDA 1056
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 94.7 bits (234), Expect = 6e-19
Identities = 205/931 (22%), Positives = 322/931 (34%), Gaps = 135/931 (14%)
Query: 468 VTEEGLALGQESTATVTPHTL-----QVAPGLQVEVATRVTPQAG-------EEETDSTA 515
V E G L TP T +V+ ++ A + P+ +ET T
Sbjct: 219 VDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTV 278
Query: 516 GQESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLT-LCPDSPQNLKEEGGLDLP 574
+E+ + + G+E T+ K E+TS L P S K +
Sbjct: 279 NKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETT 338
Query: 575 SGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPK-PVAAATIVSQQAEEG 633
+ A P++ T P++ A T P T + SAP P A ++ A
Sbjct: 339 TK----GPALTTPKEPTP--TTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTT 392
Query: 634 LTLPQDSVMTPPLPLQDTE----LSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQ 689
P + P P E + P P + + E T P+ A T P
Sbjct: 393 PKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA 452
Query: 690 DTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPL-PLQDTDLSSAPK-PVAAATLVS 747
T P P E T P++ A T P P T AP P A +
Sbjct: 453 PTT-PKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTT 511
Query: 748 QQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQA------EEGLTLPQDSA 801
+ E T P++ A T T AP +A ++ E T P++ A
Sbjct: 512 K--EPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPA 569
Query: 802 -MTPPLPLQDTDLSSAP----KPVAAAT---IVSQQAEEGLTLPQDSAMTPPLPLQDTDL 853
TP P T AP +P T + E T P+++A T P L T
Sbjct: 570 PTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPT-- 627
Query: 854 SSAPKPVAAATPVSQQAEEGLTLPQDSA-MTPPLPLQDTDLSSAPKPVAAATPVSQQAEE 912
P+ +A TP + T P++ A TP P T AP AA P + E
Sbjct: 628 --TPEKLAPTTP----EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAP-NTPKEP 680
Query: 913 GLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGT--EPVATMAQQEVG 970
T P++ A T P ++ PT+ P+ A TP+ G AP T EP T ++
Sbjct: 681 APTTPKEPAPTTP---KEPAPTT-PKETAPTTPK------GTAPTTLKEPAPTTPKKPAP 730
Query: 971 EALGP------------RPAPEEKNAALPTVP-EPAALDQVQQDDPQPAAEAGT-PWAAQ 1016
+ L P +PAP PT P EPA +P P GT P +
Sbjct: 731 KELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA---PTTPKEPAPTTPKGTAPTTLK 787
Query: 1017 EDA--------------DSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGD 1062
E A +T G + + +PA +E A + + A T
Sbjct: 788 EPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTP 847
Query: 1063 GAKPDSPQ--------KETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEV 1114
P + KE + + L+ E P+ AL + + P P P
Sbjct: 848 ETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPK-ALENSPKEPGVPTTKTPAA 906
Query: 1115 SQARLLSPARE---ERGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAP 1171
++ + + A++ ER L ++TPE T + T+ + + +++ +++
Sbjct: 907 TKPEMTTTAKDKTTERDL--RTTPETTTAAPKMTKETATTTEKTTESKITA-------TT 957
Query: 1172 APTSAPTSQQPEP--VLGLGSVEQPHEV----PSVLGTPLLQPPENLAKGQPSTPVDRPL 1225
++ T+Q P + L + +V ++ T ++ PE AK + +
Sbjct: 958 TQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKAT 1017
Query: 1226 GPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAAAAVS 1285
P P P P P + P+ ++ P + P P S
Sbjct: 1018 TPKPQK---------PTKAPKKPTSTKKPK--TMPRVRKPKTTPTPRKMTSTMPELNPTS 1066
Query: 1286 GTTQP-LGTGPRVSLSPHSPLLSPKVASMDA 1315
+ L T R + +P+S L+ S DA
Sbjct: 1067 RIAEAMLQTTTRPNQTPNSKLVEVNPKSEDA 1097
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 90.1 bits (222), Expect = 1e-17
Identities = 216/890 (24%), Positives = 308/890 (34%), Gaps = 154/890 (17%)
Query: 603 TPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAA 662
TPP P++ LS AP P +++ + G T P + T ++ P P A
Sbjct: 1109 TPPAPVR---LSPAPPPGSSSLLKPLTVPPGYTFPPAAATTTSTTTATATTTAVPAPTPA 1165
Query: 663 ATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAA----TLVSQQAEEGLTLP- 717
+ + LP ++ S A +PVA A L Q LTL
Sbjct: 1166 PQRLILSPDMQARLPSGEVVSI-----GQLASLAQRPVANAGGSKPLTFQIQGNKLTLTG 1220
Query: 718 ---QDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTP-PLPLQDTDL 773
+ A+ P PLQ ++ L+SQ A + L Q A TP P P+
Sbjct: 1221 AQVRQLAVGQPRPLQ-RNVVHLVSAGGQHHLISQPAH--VALIQAVAPTPGPTPVSVLP- 1276
Query: 774 SSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDL-----SSAPK----PVAAAT 824
SS P A T GL+LP + PP + +T + AP+ PV
Sbjct: 1277 SSTPSTTPAPT--------GLSLPLAANQVPPTMVNNTGVVKIVVRQAPRDGLTPVPPLA 1328
Query: 825 IVSQQAEEGL--TLPQDSAMTP---PLPLQDTDLSSAPKPVAAATPV----SQQAEEGLT 875
+ GL L +TP P P T + P P + S E +
Sbjct: 1329 PAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSAS 1388
Query: 876 LPQDSAMTPPLPLQDTDL----SSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDT 931
P + +T PL +S+P P+ ++P++ +++P S++ +P
Sbjct: 1389 APGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLP 1448
Query: 932 GPTSGPEPLAVATPQTLQAE---------------AGCAPGTEPVATMAQQEVGEA--LG 974
P S P + ++ P T+ A APG +A A LG
Sbjct: 1449 APASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLG 1508
Query: 975 PRPAPEEKNAALPTVP---------------------EPAALDQVQQDDPQPAAEAGTPW 1013
AP ++ P P P + P P+A P
Sbjct: 1509 LATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPA 1568
Query: 1014 AAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKET 1073
A A ++ +AL+ P A + A S A L A GA P +T
Sbjct: 1569 QASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLA-PSPGAAPVLASSQT 1627
Query: 1074 LEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKS 1133
+ +A P ++L A VP P P +Q L +P
Sbjct: 1628 ---------PVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAP----------- 1667
Query: 1134 TPEPTLPSAVATE------ASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLG 1187
P P LPS +T+ A + SS SL G P P PT S P L
Sbjct: 1668 VPSP-LPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQT-LSLTPASSL- 1724
Query: 1188 LGSVEQPHEVPSVLGTPLLQPPE--NLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEP 1245
V P + S+ P L P + +LA P P P+GP P+ TLA P
Sbjct: 1725 ---VPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPAS-PVGPAPAHTLTLA-----PASS 1775
Query: 1246 PAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPR--VSLSPHS 1303
A L + P +LG A Q A A + T P VS S +
Sbjct: 1776 SASLLAPASVQTLTLSPAPVPTLG----PAAAQTLALAPASTQSPASQASSLVVSASGAA 1831
Query: 1304 PL----LSPKVASMDAKD-LALQILPPCQVPPPSGPQSPAGPQGLSAPEQQEDE----DS 1354
PL +S S D D L L+ PP PPS S GP+ P DS
Sbjct: 1832 PLPVTMVSRLPVSKDEPDTLTLRSGPP---SPPSTATSFGGPRPRRQPPPPPRSPFYLDS 1888
Query: 1355 LEEDSPRALGSG-----QHSDSHGESSAELDEQDILAPQTVQCPAQAPAG 1399
LEE R Q S++HG + A + ++L T+ P +P G
Sbjct: 1889 LEEKRKRQRSERLERIFQLSEAHG-ALAPVYGTEVLDFCTLPQPVASPIG 1937
Score = 89.4 bits (220), Expect = 3e-17
Identities = 230/994 (23%), Positives = 338/994 (34%), Gaps = 185/994 (18%)
Query: 91 PSPMLLPEGLSSQALSTEAPLPATLEPRIVMGEETCQALLSPRAARTALRDQEGGHASPD 150
P P P+ + + P+P E R V+ +A L P R P
Sbjct: 981 PDPPPRPKPVKMKVNRMLQPVPKQ-EGRTVVVVNNPRAPLGPVPVR------------PP 1027
Query: 151 PPPELCSQGDLSVPSPPPDPDSFFTPPSTPTKTTYA---LLPACGPHGDARDSEAELRDE 207
P PEL +Q P+P P P P S + A L+PA P G +
Sbjct: 1028 PGPELSAQ-----PTPGPVPQVL--PASLMVSASPAGPPLIPASRPPGPVLLPPLQPNSG 1080
Query: 208 LLDSPPASPSGSYITADGDSWASSPSCSLSLLAPAEGLDFPSGWGLSPQGSMVDERELH- 266
L SP G G S +P+ SL PA P+ P GS + L
Sbjct: 1081 SLPQVLPSPLG---VLSGTSRPPTPTLSLKPTPPAPVRLSPA----PPPGSSSLLKPLTV 1133
Query: 267 PAGTPEPPSSESSLSADSSSSWGQEGHFFDLDFLANDPMIPAALLPFQGSLIFQVEAVEV 326
P G PP++ ++ S +++ A +PA P LI
Sbjct: 1134 PPGYTFPPAAATTTSTTTAT--------------ATTTAVPAPT-PAPQRLI-------- 1170
Query: 327 TPLSPEEEEEEAVADPDPGGDLAGEGEEDSTSASFLQSLSDLSITE-GMDEAFAFRDDTS 385
LSP+ + P G++ G+ L SL+ + G + F+
Sbjct: 1171 --LSPDMQARL------PSGEVVSIGQ--------LASLAQRPVANAGGSKPLTFQ---- 1210
Query: 386 AASSDSDSASYAEADDERLYSGEPHAQATLLQDSVQKTEEESGGGAKGLQAQDGTVSWAV 445
+ + A +L G+P LQ +V S GG L +Q V+
Sbjct: 1211 ---IQGNKLTLTGAQVRQLAVGQPRP----LQRNV--VHLVSAGGQHHLISQPAHVALIQ 1261
Query: 446 EAAPQTSDRGAYLSQRQELISEVTEEGLALGQESTATVTPHTLQVAPGLQVEVATRVTPQ 505
AP + + GL+L A P T+ G+ V++ R P+
Sbjct: 1262 AVAPTPGPTPVSVLPSSTPSTTPAPTGLSL--PLAANQVPPTMVNNTGV-VKIVVRQAPR 1318
Query: 506 AGEEETDSTAGQESAAMAMPQPSQEGISEILG-QESVTAEKLPTPQEETSLTLCPD---- 560
G A P+P G+ +L + ++T +LPTP T+ P
Sbjct: 1319 DGLTPVPPLA-------PAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLV 1371
Query: 561 ----------SPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQD 610
SP+ G + P+ + +P A + +P S + P+
Sbjct: 1372 RPLLKLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTV 1431
Query: 611 TDLSSAPKPVAAATIVSQQAEEGLTLPQDSVM-------------TPPLPLQDTELSSAP 657
+ S+ P++ T + A LT+P + + TPPL + +AP
Sbjct: 1432 SVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLA---PVVPAAP 1488
Query: 658 KPVAAATLVSQQAEEGLTL------PQDSAMTP--PLPLQDTD-----LSSAPKPVAAAT 704
P + A + + LTL S+ TP PL L T L+S P +
Sbjct: 1489 GPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPV 1548
Query: 705 LVSQQAEEGLTLPQDSAMTPPLPLQDTDL---SSAPKPVAAATLVSQQAEEGLTLPQDSA 761
LV A L P SA P P Q + L SSA + +A + + P +
Sbjct: 1549 LVPASA---LASPFPSAPN-PAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAP 1604
Query: 762 MTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVA 821
PLP+ AP P AA + S Q + P + TP L AP PV
Sbjct: 1605 PLAPLPV------LAPSPGAAPVLASSQTPVPVMAP---SSTPGTSLASASPVPAPTPVL 1655
Query: 822 AATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSA 881
A + + L P S + P Q L+ A P + SQ G PQ
Sbjct: 1656 APS----STQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPF 1711
Query: 882 MT------------------------PPL-PLQDTDLSSAPKPVAAATPVSQQAEEGLTL 916
T PPL P Q L+ AP P+A A+PV LTL
Sbjct: 1712 PTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAP-PLAPASPVGPAPAHTLTL 1770
Query: 917 -PQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPVATMAQQEVGEALGP 975
P S+ + P T P P+ P Q A T+ A+ A V A G
Sbjct: 1771 APASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLALAPASTQSPASQASSLVVSASGA 1830
Query: 976 RPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEA 1009
P P + LP + ++ P P + A
Sbjct: 1831 APLPVTMVSRLPVSKDEPDTLTLRSGPPSPPSTA 1864
Score = 84.3 bits (207), Expect = 8e-16
Identities = 204/825 (24%), Positives = 298/825 (36%), Gaps = 154/825 (18%)
Query: 617 PKPVA---AATIVSQQAEEGLTLPQDSVMTPPLPLQDTEL-----SSAPK----PVAAAT 664
P PV+ ++T + A GL+LP + PP + +T + AP+ PV
Sbjct: 1269 PTPVSVLPSSTPSTTPAPTGLSLPLAANQVPPTMVNNTGVVKIVVRQAPRDGLTPVPPLA 1328
Query: 665 LVSQQAEEGL--TLPQDSAMTP---PLPLQDTDLSSAPKPVAAATLV----SQQAEEGLT 715
+ GL L +TP P P T + P P L+ S E +
Sbjct: 1329 PAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSAS 1388
Query: 716 LPQDSAMTPPLPLQDTDL----SSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDT 771
P + +T PL +S+P P+ ++ ++ +++P S++ +P
Sbjct: 1389 APGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLP 1448
Query: 772 DLSSAPK--PVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQ 829
+SAP P++A VS LT ++TPPL + +AP P + A +
Sbjct: 1449 APASAPLTIPISAPLTVSASGPALLT-----SVTPPLA---PVVPAAPGPPSLAPSGASP 1500
Query: 830 AEEGLTL------PQDSAMTP--PLPLQDTD-----LSSAPKPVAAATPVSQQAEEGLTL 876
+ LTL S+ TP PL L T L+S P A +PV A L
Sbjct: 1501 SASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAP--ACSPVLVPAS-ALAS 1557
Query: 877 PQDSAMTPPLPLQDTDLSSAPKPVAA-ATPVSQQA--EEGLTLPQDSAMTAPLPLQDTGP 933
P SA P P Q + L+ A A ATP++ A + + P + APLP+ P
Sbjct: 1558 PFPSAPNPA-PAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSP 1616
Query: 934 TSGPEPLAVATPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPA 993
+ P + TP + A P + P ++A A P AP LP P P+
Sbjct: 1617 GAAPVLASSQTPVPVMA-----PSSTPGTSLASASPVPAPTPVLAPSSTQTMLPA-PVPS 1670
Query: 994 ALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGREAC 1053
L A A P TL + + G + LS +
Sbjct: 1671 PLPSPASTQTLALAPALAPTLGGSSPSQTLSLGT------GNPQGPFPTQTLSLTPASSL 1724
Query: 1054 LEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACPE 1113
+ A T A P P T Q L P A P S +G A P P
Sbjct: 1725 VPTPAQTLSLA-PGPPLGPT------QTLSLAP-APPLAPASPVGPA---PAHTLTLAPA 1773
Query: 1114 VSQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAP 1173
S A LL+PA + L+ P PTL A A +L APA
Sbjct: 1774 SSSASLLAPASVQT-LTLSPAPVPTLGPAAAQTLAL--------------------APAS 1812
Query: 1174 TSAPTSQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPG 1233
T +P SQ V+ S P V V P+ +K +P T R P P +
Sbjct: 1813 TQSPASQASSLVVS-ASGAAPLPVTMVSRLPV-------SKDEPDTLTLRSGPPSPPSTA 1864
Query: 1234 TLAGAALPPLEPPAPCLCQDPQE----DSVEDE----------------EPPGSLG---- 1269
T G P +PP P P+ DS+E++ E G+L
Sbjct: 1865 TSFGGPRPRRQPPPP-----PRSPFYLDSLEEKRKRQRSERLERIFQLSEAHGALAPVYG 1919
Query: 1270 --------LPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLA-- 1319
LP P A P G + P T + + H +L P+ ++
Sbjct: 1920 TEVLDFCTLPQPVAS--PIGPRSPGPSHP--TFWTYTEAAHRAVLFPQQRLDQLSEIIER 1975
Query: 1320 -LQILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDS-PRA 1362
+ ++PP + PPPS P AP Q ++ L + PRA
Sbjct: 1976 FIFVMPPVEAPPPS--LHACHPPPWLAPRQAAFQEQLASELWPRA 2018
Score = 70.9 bits (172), Expect = 9e-12
Identities = 195/900 (21%), Positives = 302/900 (33%), Gaps = 163/900 (18%)
Query: 606 LPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATL 665
+PL++ SS P ++ EE + Q ++ L + E A A
Sbjct: 2212 MPLEEPSSSSVPS-------APEEEEETVASKQTHILEQALCRAEDEEDIRAATQAKAEQ 2264
Query: 666 VSQQAE--EGLTLPQDSAMTPPLP-LQDTDLSSAPKPVAAA----TLVSQQAEEGLTLPQ 718
V++ AE E P P +D ++S A + +AA T + + A + L
Sbjct: 2265 VAELAEFNENDGFPAGEGEEAGRPGAEDEEMSRAEQEIAALVEQLTPIERYAMKFLEASL 2324
Query: 719 DSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDT------- 771
+ L + + +A K + Q EE LPQ+ P + +
Sbjct: 2325 EEVSREELKQAEEQVEAARKDL------DQAKEEVFRLPQEEEEGPGAGDESSCGTGGGT 2378
Query: 772 --DLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQ 829
A P T VS++ Q + TP + T ++ P + A ++
Sbjct: 2379 HRRSKKAKAPERPGTRVSERLRGARAETQGANHTPVISAHQTRSTTTPPRCSPAR---ER 2435
Query: 830 AEEGLTLPQDSAMTPP--LPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTPPLP 887
P+ + + P +P SAP P++A P++ LP +PP P
Sbjct: 2436 VPRPAPRPRPTPASAPAAIPALVPVPVSAPVPISAPNPIT-------ILPVHILPSPPPP 2488
Query: 888 LQDTDLSS-APKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGP-------EP 939
Q SS A P A TP P + + P GP S P P
Sbjct: 2489 SQIPPCSSPACTPPPACTPPPAHTPP----PAQTCLVTPSSPLLLGPPSVPISASVTNLP 2544
Query: 940 LAVATPQTLQAEAGCAPGTEPVATMAQQEVGE------------ALGPRPAPEEKNAALP 987
L + L A+A +P + +A++A E A+ P E+ + P
Sbjct: 2545 LGLRPEAELCAQALASPESLELASVASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTP 2604
Query: 988 TVP----EPAALDQVQQDDPQPAAEAGTPWAAQEDAD---------------STLGMEAL 1028
+ P E ++ Q+ + +AE T E + S E L
Sbjct: 2605 SAPSLTLEAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAASDEPL 2664
Query: 1029 SLPEPASGAGEEIAEALS------RPGREACLEARAHTGDGAKPDSPQ----------KE 1072
P A EE+ EA + +P E A + + SP+ +
Sbjct: 2665 QEPLEADRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPARPPRRRT 2724
Query: 1073 TLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGK 1132
+ +VE + +G +P Q GP + + P V + L+ R++RG +
Sbjct: 2725 SADVEIRGQGTGRP-GQPPGP-------KVLRKLPGRLVTVVEEKELVRRRRQQRGAAST 2776
Query: 1133 STPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEP-------- 1184
P + SA S+ S G SS G P AP+S+ + +P
Sbjct: 2777 LVPGVSETSASPGSPSV----RSMSGPESSPPIGGPCEAAPSSSLPTPPQQPFIARRHIE 2832
Query: 1185 --VLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAG----- 1237
V G GS E + P ++ + +P D G D + TL G
Sbjct: 2833 LGVTGGGSPENGDGALLAITPPAVKRRRGRPPKKNRSPADAGRGVDEAPSSTLKGKTNGA 2892
Query: 1238 ----------AALPPLEP----------PAPCLCQDPQEDSVEDE---EPPGSLGLPPPQ 1274
A P LEP P P +P VE PP + LP P
Sbjct: 2893 DPVPGPETLIVADPVLEPQLIPGPQPLGPQPVHRPNPLLSPVEKRRRGRPPKARDLPIPG 2952
Query: 1275 AGVQPAAAAVSGTTQPLGTGPRVS-LSPHSPLLSPKVASM--DAKDLALQILPPCQV--P 1329
TQP P S L+P PLL A++ + + PP +
Sbjct: 2953 TISSAGDGNSESRTQP---PPHPSPLTPLPPLLVCPTATVANTVTTVTISTSPPKRKRGR 3009
Query: 1330 PPSGPQSPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELDEQDILAPQT 1389
PP P SP Q P D S+ E LG + GES ++D P T
Sbjct: 3010 PPKNPPSPRPSQ---LPVLDRDSTSVLESC--GLGRRRQPQGQGESEGSSSDEDGSRPLT 3064
Score = 59.3 bits (142), Expect = 3e-08
Identities = 113/481 (23%), Positives = 173/481 (35%), Gaps = 79/481 (16%)
Query: 951 EAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAG 1010
EAG + + A+QE+ AL + P E+ A A+L++V +++ + A E
Sbjct: 2284 EAGRPGAEDEEMSRAEQEIA-ALVEQLTPIERYAMKFL---EASLEEVSREELKQAEEQV 2339
Query: 1011 TPWAAQEDADSTLGMEALSLP---EPASGAGEEIAEALSRPGREACLEARAHTGDGAKPD 1067
AA++D D E LP E GAG+E + TG G
Sbjct: 2340 E--AARKDLDQAKE-EVFRLPQEEEEGPGAGDE---------------SSCGTGGGT--- 2378
Query: 1068 SPQKETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREER 1127
+ + + + + G + + G R+ GA P + SPARE R
Sbjct: 2379 --HRRSKKAKAPERPGTRVSERLRGARAETQGANHTPVISAHQTRSTTTPPRCSPARE-R 2435
Query: 1128 GLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLD-------RGCPDAPAPTSAPTSQ 1180
P PT SA A +L P S+ +S+ + P P P+ P
Sbjct: 2436 VPRPAPRPRPTPASAPAAIPALVPVPVSAPVPISAPNPITILPVHILPSPPPPSQIPPCS 2495
Query: 1181 QPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTPV-----DRPLGPDPSAPGTL 1235
P P P T L+ P L G PS P+ + PLG P A
Sbjct: 2496 SPACTPPPACTPPPAHTPPPAQTCLVTPSSPLLLGPPSVPISASVTNLPLGLRPEAELCA 2555
Query: 1236 AGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGP 1295
A P + + SV E SL L PP+ + P A + ++
Sbjct: 2556 QALASP----------ESLELASVASSE-TSSLSLVPPK-DLLPVAVEILPVSE-----K 2598
Query: 1296 RVSLSPHSPLLSPKVASM----------DAKDLALQILPPCQVPPPSGPQSPAGPQGLSA 1345
+SL+P +P L+ + S+ A+ L +LP + P +S GL
Sbjct: 2599 NLSLTPSAPSLTLEAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSES----NGLEL 2654
Query: 1346 PEQQEDEDSLEED-----SPRALGSGQHSDSHGESSAELDEQDILAPQTVQCPAQAPAGG 1400
P ++ L+E + L + S E EL ++ AP T +P G
Sbjct: 2655 PPSAASDEPLQEPLEADRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGP 2714
Query: 1401 S 1401
S
Sbjct: 2715 S 2715
Score = 45.8 bits (107), Expect = 3e-04
Identities = 82/302 (27%), Positives = 113/302 (37%), Gaps = 58/302 (19%)
Query: 13 PEADRPGP-RTDLSCDAAAATTILGGDRREPCALTPGPSHLALTFLPSKPGARPQPEGAS 71
P A P P + L A++A+ L P A P L P+ P A P P A
Sbjct: 1560 PSAPNPAPAQASLLAPASSASQALA----TPLAPMAAPQTAILAPSPAPPLA-PLPVLAP 1614
Query: 72 WDAGPGGAPSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIVMGEETCQALL- 130
PG AP + P P++ P +L++ +P+PA P V+ + Q +L
Sbjct: 1615 ---SPGAAPVLASSQT---PVPVMAPSSTPGTSLASASPVPA---PTPVLAPSSTQTMLP 1665
Query: 131 --------SPRAART-----ALRDQEGGHASPDPPPELCSQGDLSVPSPPPDPDSFFTPP 177
SP + +T AL GG + P + S G + P P TP
Sbjct: 1666 APVPSPLPSPASTQTLALAPALAPTLGGSS----PSQTLSLGTGNPQGPFPTQTLSLTPA 1721
Query: 178 S----TPTKT-TYALLPACGPHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSP 232
S TP +T + A P GP L +PP +P+ A + +P
Sbjct: 1722 SSLVPTPAQTLSLAPGPPLGPTQTL---------SLAPAPPLAPASPVGPAPAHTLTLAP 1772
Query: 233 -SCSLSLLAPAEGLDFPSGWGLSPQ------GSMVDERELHPAGTPEPPSSESSLSADSS 285
S S SLLAPA LSP + L PA T P S SSL +S
Sbjct: 1773 ASSSASLLAPASVQTLT----LSPAPVPTLGPAAAQTLALAPASTQSPASQASSLVVSAS 1828
Query: 286 SS 287
+
Sbjct: 1829 GA 1830
Score = 36.2 bits (82), Expect = 0.25
Identities = 61/262 (23%), Positives = 100/262 (38%), Gaps = 47/262 (17%)
Query: 198 RDSEAELRDELLDSPP------ASPSGSYITADGDSWASSPSCSLSLLAPAEGLDF--PS 249
R+ E L + L PP +SPS + + D D+ P EG + P
Sbjct: 326 REGELPLEELLRSLPPQLLEGPSSPSQTPSSHDSDTRDG----------PEEGAEEEPPQ 375
Query: 250 GWGLSPQGSMVDERELHP-----------AGTPEPPSSESSLSADSSSSWGQEGHFFDLD 298
+ P S V +R P A E E +++A+ G+ H +L
Sbjct: 376 VLEIKPPPSAVTQRNKQPWHPDEDDEEFTANEEEAEDEEDTIAAEEQLE-GEVDHAMELS 434
Query: 299 FLANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEEAV----ADPDPGGDLAGEGEE 354
LA + L + L A S E+E+E+ V +D +P G + E
Sbjct: 435 ELARE-----GELSMEELLQQYAGAYAPGSGSSEDEDEDEVDANSSDCEPEGPVEAEEPP 489
Query: 355 DSTSASFLQSLSDLSITEGMDEAFAFRDDTSAASSDS------DSASYAEADDERLYSGE 408
S+S S+ D S E + + S+AS +S D+ S ++AD+E +
Sbjct: 490 QEDSSSQSDSVEDRSEDEEDEHSEEEETSGSSASEESESEESEDAQSQSQADEEE--EDD 547
Query: 409 PHAQATLLQDSVQKTEEESGGG 430
LL +++E ++G G
Sbjct: 548 DFGVEYLLARDEEQSEADAGSG 569
Score = 36.2 bits (82), Expect = 0.25
Identities = 167/729 (22%), Positives = 234/729 (32%), Gaps = 128/729 (17%)
Query: 44 ALTPGPSHLALTFLPSK-PGARPQPEGASWDAGPGGAPSAWAD------------PGEG- 89
A TPGP+ +++ LPS P P P G S P + P +G
Sbjct: 1264 APTPGPTPVSV--LPSSTPSTTPAPTGLSLPLAANQVPPTMVNNTGVVKIVVRQAPRDGL 1321
Query: 90 GPSPMLLPEGLSSQALSTEAPLPATLEPRIVMGE-----ETCQALLSPRAARTALRDQEG 144
P P L P + LPA L PR + T +P T +R
Sbjct: 1322 TPVPPLAPA-----PRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLK 1376
Query: 145 GHASPDPPPELCSQG--DLSVPSPPPDPDSFFTPPSTPTKTTYALLPACGPHGDARDSEA 202
SP P + G L++ SP P S P S+P +P P S
Sbjct: 1377 LVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMP-----IPNSSPLASPVSSTV 1431
Query: 203 ELR---------DELLDSPPASPSGSYITADGDSWASSPSCSLSLLAPAEGL--DFPSGW 251
+ L +P ++P I+A AS P+ S+ P + P
Sbjct: 1432 SVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPP 1491
Query: 252 GLSPQGSMVDERELHPAGTPEPPSSESS-------LSADSSSSWGQEGHFFDLDFLANDP 304
L+P G+ L G PS SS L A +SS G + +
Sbjct: 1492 SLAPSGASPSASAL-TLGLATAPSLSSSQTPGHPLLLAPTSSH--VPGLNSTVAPACSPV 1548
Query: 305 MIPAALL-----------PFQGSLIFQVEAVE---VTPLSPEEEEEEAVADPDPGGDLAG 350
++PA+ L P Q SL+ + TPL+P + A+ P P LA
Sbjct: 1549 LVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLA- 1607
Query: 351 EGEEDSTSASFLQSLSDLSITEGMDEAFAFRDD--TSAASSDSDSASYAEADDERLYSGE 408
L L+ + G A A S + S A A S
Sbjct: 1608 -------------PLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASA------SPV 1648
Query: 409 PHAQATLLQDSVQKTEEESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLSQRQEL---- 464
P L S Q A T++ A AP G+ SQ L
Sbjct: 1649 PAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLG--GSSPSQTLSLGTGN 1706
Query: 465 -ISEVTEEGLALGQESTATVTP-HTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAM 522
+ L+L S+ TP TL +APG P G +T S A A
Sbjct: 1707 PQGPFPTQTLSLTPASSLVPTPAQTLSLAPG----------PPLGPTQTLSLAPAPPLAP 1756
Query: 523 AMPQPSQEGISEILGQESVTAEKLPTPQEETSLTLCPDSPQNLKEEGGLDL----PSGRK 578
A P + L S +A L P +LTL P L L S +
Sbjct: 1757 ASPVGPAPAHTLTLAPASSSASLL-APASVQTLTLSPAPVPTLGPAAAQTLALAPASTQS 1815
Query: 579 PVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDL----SSAPKPVAAATIVSQQAEEGL 634
P + A+ + A LP P+ + D S P P + AT
Sbjct: 1816 PASQASSLVVSASGAAPLPVTMVSRLPVSKDEPDTLTLRSGPPSPPSTATSFGG------ 1869
Query: 635 TLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQ-DSAMTPPLPLQDTDL 693
P+ PP P L S + S++ E L + A+ P + D
Sbjct: 1870 --PRPRRQPPPPPRSPFYLDSLEEKRKRQR--SERLERIFQLSEAHGALAPVYGTEVLDF 1925
Query: 694 SSAPKPVAA 702
+ P+PVA+
Sbjct: 1926 CTLPQPVAS 1934
Score = 33.1 bits (74), Expect = 2.2
Identities = 44/168 (26%), Positives = 58/168 (34%), Gaps = 26/168 (15%)
Query: 1224 PLGPDPSAPGTLAGAALPPLEPPAPCL--------CQDPQEDSVEDEEPPGSLGLPP--P 1273
PLGP P P + P P P + + PPG + LPP P
Sbjct: 1018 PLGPVPVRPPPGPELSAQPTPGPVPQVLPASLMVSASPAGPPLIPASRPPGPVLLPPLQP 1077
Query: 1274 QAGVQPAA-----AAVSGTTQPLGTGPRVSLSPHSPL---LSPKVASMDAKDLALQILPP 1325
+G P +SGT++P P +SL P P LSP + L +PP
Sbjct: 1078 NSGSLPQVLPSPLGVLSGTSRP--PTPTLSLKPTPPAPVRLSPAPPPGSSSLLKPLTVPP 1135
Query: 1326 CQVPPP------SGPQSPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQ 1367
PP S + A + AP L D L SG+
Sbjct: 1136 GYTFPPAAATTTSTTTATATTTAVPAPTPAPQRLILSPDMQARLPSGE 1183
Score = 31.6 bits (70), Expect = 6.3
Identities = 63/263 (23%), Positives = 83/263 (31%), Gaps = 57/263 (21%)
Query: 90 GPSPMLLPEGLSSQALSTEAPLPATLEPRIVMGEETCQALLSPRAARTALRDQEGGHASP 149
GP P+ P G A T P+P L +++ L P AS
Sbjct: 1020 GPVPVRPPPGPELSAQPTPGPVPQVLPASLMVSASPAGPPLIP--------------ASR 1065
Query: 150 DPPPEL---CSQGDLSVPSPPPDPDSFFTPPSTPTKTTYALLPACGPHGDARDSEAELRD 206
P P L S+P P P + S P T +L P P R S
Sbjct: 1066 PPGPVLLPPLQPNSGSLPQVLPSPLGVLSGTSRPPTPTLSLKPT--PPAPVRLS------ 1117
Query: 207 ELLDSPPASPSGSYITADGDSWASSPSCSLSLLAPAEGLDFPSGWGLSPQGSMVDERELH 266
PA P G S SLL P L P G+ P +
Sbjct: 1118 ------PAPPPG----------------SSSLLKP---LTVPPGYTFPPAAATTTSTTTA 1152
Query: 267 PAGT-----PEPPSSESSLSADSSSSWGQEGHFFDLDFLANDPMIPAALLPFQGSLIFQV 321
A T P P LS D + G + LA+ P A L FQ+
Sbjct: 1153 TATTTAVPAPTPAPQRLILSPDMQARL-PSGEVVSIGQLASLAQRPVANAGGSKPLTFQI 1211
Query: 322 EAVEVTPLSPEEEEEEAVADPDP 344
+ ++T L+ + + AV P P
Sbjct: 1212 QGNKLT-LTGAQVRQLAVGQPRP 1233
>gi|167736355 mucin 4 isoform a [Homo sapiens]
Length = 5284
Score = 89.4 bits (220), Expect = 3e-17
Identities = 283/1259 (22%), Positives = 398/1259 (31%), Gaps = 208/1259 (16%)
Query: 90 GPSPMLLPEGLSSQALSTEAPLPATLEPRIVMGEETCQALLSPRAARTALRDQEGGHASP 149
G + LL SS + PLP T G T + SP +A T GHA+P
Sbjct: 1468 GQATSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSAST-------GHATP 1520
Query: 150 DPPPEL--CSQGDLSVPSPPPDPDSFFTPPSTPTKTTYALLPACGPHGDARDSEAELRDE 207
P L S GD ++P P P S T +TP T DA
Sbjct: 1521 LPVTSLSSASTGD-TMPLPVTSPSSASTGDTTPLPVT-----------DASSVSTGHTTP 1568
Query: 208 LLDSPPASPSGSYIT----ADGDSWASSPSCSLSLLAPAEGLDFPSGWGLSPQGSMVDER 263
L + P+S S + T D S + + L + +P+ + G + + D
Sbjct: 1569 LPVTSPSSASTGHTTPLPVTDTSSASKGDTTPLPVTSPSS-----ASTGHTTPLPVTDTS 1623
Query: 264 ELHPAG-TPEPPSSESSLSAD-------SSSSWGQEGHFFDLDFLANDPMIP--AALLPF 313
TP P ++ SSLS +S S GH L + A LP
Sbjct: 1624 SASTGDTTPLPVTNASSLSTGHATPLHVTSPSSASTGHATPLPVTSTSSASTGHATPLPV 1683
Query: 314 QGSLIFQVEAVEVTPLSPEEEEEEAVADPDPGGDLAGEGEEDSTSASFLQSLSDLSITEG 373
G + P++ A P P L+ D+T L S S + G
Sbjct: 1684 TGLSSATTDDTTRLPVTDVSSASTGQATPLPVTSLSSVSTGDTTP---LPVTSPSSASTG 1740
Query: 374 MDEAFAFRDDTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSVQKTEEESGGGAKG 433
D +SA++ + + P L S T
Sbjct: 1741 HASPLLVTDASSASTGQATPLPVTDTSSVSTAHATPLPVTGLSSASTDDTTR-------- 1792
Query: 434 LQAQDGTVSWAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQESTATVTPHTLQVAPG 493
L D + + +A P + S VT+ A ++T+ + G
Sbjct: 1793 LPVTDVSSASTGQAIPLPVTSPSSASTGDTTPLPVTDASSASTGDTTSLPVTIPSSASSG 1852
Query: 494 ----LQVEVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQES---VTAEKL 546
L V A+ V+ + A S P P + S G + VT
Sbjct: 1853 HTTSLPVTDASSVSTGHATSLLVTDASSVSTGDTTPLPVTDTNSASTGDTTPLHVTDASS 1912
Query: 547 PTPQEETSLTLCPDSPQNLKEEGGLDLPSGRK---------PVAAATIVPRQAKEDLTLP 597
+ TSL + S + + L + S PV A+ VP L +
Sbjct: 1913 VSTGHATSLPVTSLSSASTGDTTPLPVTSPSSASSGHTTPLPVTDASSVPTGHATSLPVT 1972
Query: 598 QDSAMT----PPLPLQDTDLSS----APKPVAAATIVSQQAEEGLTLPQDSVM------T 643
S+++ PLP+ D S P PV + VS + LP S+ T
Sbjct: 1973 DASSVSTGHATPLPVTDASSVSTGHATPLPVTDTSSVS--TGQATPLPVTSLSSASTGDT 2030
Query: 644 PPLPLQDTELSS----APKPVAAATLVSQQAEEGL--TLPQDSAMTPPLPLQDTDLSSAP 697
PLP+ DT +S P PV + + VS L T P ++ PL TD SS
Sbjct: 2031 TPLPVTDTSSASTGQDTPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSVS 2090
Query: 698 KPVAAATLVSQQAEEG------------------------LTLPQDSAM--TPPLPLQDT 731
A + LV+ + +T P ++ T PLP+ DT
Sbjct: 2091 TGHATSLLVTDASSVSTGHATALHVTDASSLSTGDTTPLPVTSPSSASTGDTTPLPVTDT 2150
Query: 732 DLSSAPKPVAAATLVSQQAEEG--LTLP---QDSAMT---PPLPLQDTDLSSAPKPVAAA 783
S + + A G +LP SA T PLP+ DT +S +
Sbjct: 2151 SSVSTGHATSLPVTDTSSASTGHATSLPVTDTSSASTGHATPLPVTDTSSASTGQATPLP 2210
Query: 784 TIVSQQAEEGLTLP-----QDSAMT-PPLPLQDTDLSSA------PKPVAAATIVSQQAE 831
A G +P SA T PL T LSSA P PV A+ VS
Sbjct: 2211 VTSPSSASTGHAIPLLVTDTSSASTGQATPLPVTSLSSASTGDTTPLPVTDASSVSTGHA 2270
Query: 832 EGL------------------TLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEG 873
L T P ++ PL TD SSA A PV+ +
Sbjct: 2271 TSLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLHVTDASSASTGHATPLPVTSLSSAS 2330
Query: 874 --------LTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPV--SQQAEEGLTLP------ 917
+T P ++ PL TD SS PV S A G T P
Sbjct: 2331 TGDTTPLPVTSPSSASTGHATPLHVTDASSVSTGDTTPLPVTSSSSASSGHTTPLPVTDA 2390
Query: 918 --QDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTE-PVATMAQQEVGEALG 974
+ T PLP+ DT S A P T + A T PV ++ G A
Sbjct: 2391 SSASTGDTTPLPVTDTSSASTGH--ATHLPVTGLSSASTGDTTRLPVTNVSSASTGHAT- 2447
Query: 975 PRPAPEEKNAAL-PTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLPEP 1033
P P +A+ T P P D + T DA S + LP
Sbjct: 2448 PLPVTSTSSASTGDTTPLPGT-------DTSSVSTGHTTPLLVTDASSVSTGDTTRLPVT 2500
Query: 1034 ASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKET-----LEVENQQEGGLKPLA 1088
+ + + HT D+P T L V N +
Sbjct: 2501 SPSSA-----------------STGHTTPLPVTDTPSASTGDTTPLPVTNASSLSTRHAT 2543
Query: 1089 QEH--GPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVATE 1146
H P SA G + A L +G +TP P + A+
Sbjct: 2544 SLHVTSPSSASTGHATSLPVTDTSAASTGHATPLPVTSTSSASTGDTTPLPVTDTYSAST 2603
Query: 1147 ASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQ-QPEPVLGLGSVEQPHEVPSVLGTP 1204
P + + S+ D +SA T P PV SV H P + +P
Sbjct: 2604 GQATPLPVTDTSSASTGDTTPLPVTDTSSASTGHATPLPVTNTSSVSTGHATPLHVTSP 2662
Score = 82.4 bits (202), Expect = 3e-15
Identities = 274/1261 (21%), Positives = 404/1261 (32%), Gaps = 215/1261 (17%)
Query: 84 ADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIVMGEETCQALLSPRAARTALRDQE 143
A G+ P P+ LSS + PLP T G T + +A T
Sbjct: 2793 ASTGQATPLPVT---SLSSVSTGDTTPLPVTDTSSASTGHATSLPVTDTSSAST------ 2843
Query: 144 GGHASPDPPPELCSQG----------DLSVPS-------PPPDPDSFFTPPSTPTKTTYA 186
GHA+P P + S D S S P D S T +TP T
Sbjct: 2844 -GHATPLPDTDTSSASTGHATLLPVTDTSSASIGHATSLPVTDTSSISTGHATPLHVTSP 2902
Query: 187 LLPACG-----PHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLAP 241
+ G P D + + L + P+S S + T + SS S + P
Sbjct: 2903 SSASTGHATPLPVTDTSSASTGHANPLHVTSPSSASTGHATPLPVTDTSSASTGHATPLP 2962
Query: 242 AEGLDFPSGWGLSPQGSMVDERELHPAGTPEPPSSESSLSAD-------SSSSWGQEGHF 294
L S +P TP P + SS S +S+S G
Sbjct: 2963 VTSLSSVSTGDTTPLPVTSPSSASTGHTTPLPVTDTSSASTGQATALPVTSTSSASTGDT 3022
Query: 295 FDLDFLANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEEAVADPDP----GGDLAG 350
L P + + V + TPL + P A
Sbjct: 3023 TPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSAS 3082
Query: 351 EGEEDSTSASFLQSLSD-----LSITEGMDEAFAFRD-----DTSAASSDSDSASYAEAD 400
G+ + L S+S L +T + DTS+AS+ D+ S D
Sbjct: 3083 TGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATSLPVTDTSSAST-GDTTSLPVTD 3141
Query: 401 DERLYSGEPHAQATLLQDSVQKTEEESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLSQ 460
Y+G+ + V T S G L + + A P + S
Sbjct: 3142 TSSAYTGDTTSLP------VTDTSSSSTGDTTPLLVTETSSVSTGHATPLLVTDASSAST 3195
Query: 461 RQELISEVTEEGLALGQESTATVTPHTLQVAPGLQVEVATRVTPQAGEEET------DST 514
VT A ++T T V+ G + A +T D +
Sbjct: 3196 GHATPLHVTSPSSASTGDTTPVPVTDTSSVSTGHATPLPVTGLSSASTGDTTRLPVTDIS 3255
Query: 515 AGQESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLP 574
+ A +P + +S T + +P P SP + LP
Sbjct: 3256 SASTGQATPLPVTNTSSVS--------TGDTMPLPVT---------SPSSASTGHATPLP 3298
Query: 575 SGRKPVAA---ATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSA----PKPVAAATIVS 627
A+ AT VP + T + T PLP+ DT +S P PV + + S
Sbjct: 3299 VTSTSSASTGHATPVPVTS----TSSASTGHTTPLPVTDTSSASTGDTTPLPVTSPSSAS 3354
Query: 628 QQAEEGL--TLPQDSVMTPPLPLQDTELSSA------PKPVAAATLVSQQAEEGLTLPQD 679
L T+P + L T SSA P PV + VS L +
Sbjct: 3355 TGHTTPLHVTIPSSASTGDTSTLPVTGASSASTGHATPLPVTDTSSVSTGHATPLPVTSL 3414
Query: 680 SAM----TPPLPLQDTDLSSA----PKPVAAATLVSQQAEEGLTLPQDSAMTP----PLP 727
S++ T PLP+ D +S P PV + + VS L + S+++ PLP
Sbjct: 3415 SSVSTGDTTPLPVTDASSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATPLP 3474
Query: 728 LQDT--------------DLSSA------PKPVAAATLVSQQAEEGLTLPQDSAMTP--- 764
+ DT D SSA P PV + + VS L + S+++
Sbjct: 3475 VTDTSSASTGDTTRLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHA 3534
Query: 765 -PLPLQDT------DLSSAPKPVAAATIVSQQAEEGLTLPQDSAM--TPPLPLQDTDLSS 815
PLP+ DT D + P ++ Q +T+P S+ T PLP+ T S
Sbjct: 3535 TPLPVTDTSSASTGDTTRLPVTDTSSASTGQATPLPVTIPSSSSSGHTTPLPVTSTSSVS 3594
Query: 816 A--------------------PKPVAAATIVSQQAEEGLTLPQDSAMTP--PLPLQDTDL 853
P PV + + S L + S+++ PL TD
Sbjct: 3595 TGHVTPLHVTSPSSASTGHVTPLPVTSTSSASTGHATPLLVTDASSVSTGHATPLPVTDA 3654
Query: 854 SSA------PKPVAAATPVSQQAEEGLTLPQDSAM----TPPLPLQDTDLSSAPKPVAAA 903
SSA P PV + S L + S++ T PLP+ TD SSA A
Sbjct: 3655 SSASTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPV--TDASSASTGHATP 3712
Query: 904 TPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPVAT 963
PV T+P + +PL T P+S A P T + A T T
Sbjct: 3713 LPV--------TIPSSVSTGDTMPLPVTSPSSASTGHATPLPVTGLSSASTGDTTPLPVT 3764
Query: 964 MAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTL 1023
P P + +A+ D T ++ D+T
Sbjct: 3765 DTSSASTRHATPLPVTDTSSASTDDTTRLPVTDVSSASTGHATPLPVTSTSSASTGDTT- 3823
Query: 1024 GMEALSLPEPASGAGE-EIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEG 1082
P P + A S P + +R+ G P +T V G
Sbjct: 3824 -------PLPVTDTSSVSTGHATSLP-----VTSRSSASTGHATPLPVTDTSSVST---G 3868
Query: 1083 GLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEP----- 1137
PL + G A +P P++ A + +G +TP P
Sbjct: 3869 HATPLPVTSTSSVSTGHATPLPVTSPSSA-STGHATPVPVTSTSSASTGDTTPLPVTNAS 3927
Query: 1138 TLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEV 1197
+L + AT + S +S G S+L P A +++ P P+ L SV
Sbjct: 3928 SLSTGHATPLHVTSPSSASRGDTSTL----PVTDASSASTGHATPLPLTSLSSVSTGDTT 3983
Query: 1198 P 1198
P
Sbjct: 3984 P 3984
Score = 79.7 bits (195), Expect = 2e-14
Identities = 215/935 (22%), Positives = 311/935 (33%), Gaps = 158/935 (16%)
Query: 594 LTLPQDSAM--TPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPL----- 646
+T+P ++ T PLP+ DT +S + + + G T P T
Sbjct: 1235 VTIPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSASTGHV 1294
Query: 647 -PLQDTELSSAPK----PVAAATLVSQQAEEGLTLPQDSAM------TPPLPLQD----- 690
PL T SSA P+ +L S + + LP S T PLP+ D
Sbjct: 1295 TPLHVTSPSSASTGHATPLPVTSLSSASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVS 1354
Query: 691 ---------TDLSSA------PKPVAAATLVSQQAEEGL--TLPQDSAMTPPLPLQDTDL 733
TD SSA P PV + + VS L T P ++ PL TD
Sbjct: 1355 TGHTTPLHVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDT 1414
Query: 734 SSA------PKPVAAATLVSQQAEEGL--TLPQDSAMTPPLPLQDTDLSSAPKPVAAATI 785
SSA P PV A+ VS L T+P ++ PL TD SSA A + +
Sbjct: 1415 SSASTGHATPLPVTDASSVSTDHATSLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLL 1474
Query: 786 VSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPK--PVAAATIVSQQAEEGLTLPQDSAM- 842
V+ T + T PLP+ T +S P+ + S LP S
Sbjct: 1475 VTD------TSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVTSLSS 1528
Query: 843 -----TPPLPLQDTDLSSA----PKPVAAATPVSQQAEEGL--TLPQDSAMTPPLPLQDT 891
T PLP+ +S P PV A+ VS L T P ++ PL T
Sbjct: 1529 ASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLPVTSPSSASTGHTTPLPVT 1588
Query: 892 DLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDT--GPTSGPEPLAV------- 942
D SSA K PV+ + + T PLP+ DT T PL V
Sbjct: 1589 DTSSASKGDTTPLPVTSPSS------ASTGHTTPLPVTDTSSASTGDTTPLPVTNASSLS 1642
Query: 943 ---ATPQTLQAEAGCAPGTE---PVATMAQQEVGEA-----LGPRPAPEEKNAALPTVPE 991
ATP + + + + G PV + + G A G A + LP
Sbjct: 1643 TGHATPLHVTSPSSASTGHATPLPVTSTSSASTGHATPLPVTGLSSATTDDTTRLPVTDV 1702
Query: 992 PAALDQVQQDDPQPAAEAG-------TPWAAQEDADSTLGMEALSLPEPASGAGEEIAEA 1044
+A Q P P TP + ++ G + L AS A +A
Sbjct: 1703 SSA--STGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHASPLLVTDASSA--STGQA 1758
Query: 1045 LSRPGREACLEARAHT--------GDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSA 1096
P + + AH + D+ + +V + G PL ++
Sbjct: 1759 TPLPVTDTSSVSTAHATPLPVTGLSSASTDDTTRLPVTDVSSASTGQAIPLPVTSPSSAS 1818
Query: 1097 LGGAREVP--DAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPE 1154
G +P DA A+ + + + P+ SG +T P ++ + S
Sbjct: 1819 TGDTTPLPVTDASSASTGDTTSLPVTIPSSAS---SGHTTSLPVTDASSVSTGHATSLLV 1875
Query: 1155 SSVGAVSSLDRGCPDAPAPTSAPTSQ-QPEPVLGLGSVEQPH----EVPSVLG------T 1203
+ +VS+ D SA T P V SV H V S+ T
Sbjct: 1876 TDASSVSTGDTTPLPVTDTNSASTGDTTPLHVTDASSVSTGHATSLPVTSLSSASTGDTT 1935
Query: 1204 PLLQPPENLAKGQPSTPV------DRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQED 1257
PL + A +TP+ P G S P T A + P P D
Sbjct: 1936 PLPVTSPSSASSGHTTPLPVTDASSVPTGHATSLPVTDASSVSTGHATPLP--VTDASSV 1993
Query: 1258 SVEDEEP-------PGSLGLPPPQAGVQPAAAAVSGTTQ-PLGTGPRVSLSPHSPLLSPK 1309
S P S G P ++A+ TT P+ S +PL
Sbjct: 1994 STGHATPLPVTDTSSVSTGQATPLPVTSLSSASTGDTTPLPVTDTSSASTGQDTPLPVTS 2053
Query: 1310 VASMDAKDLALQILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSPRAL---GSG 1366
++S+ D P V PS + G + P D S+ +L +
Sbjct: 2054 LSSVSTGDTT-----PLPVTSPSSAST-----GHATPLLVTDASSVSTGHATSLLVTDAS 2103
Query: 1367 QHSDSHGESSAELDEQDILAPQTVQCPAQAPAGGS 1401
S H + D + T P +P+ S
Sbjct: 2104 SVSTGHATALHVTDASSLSTGDTTPLPVTSPSSAS 2138
Score = 78.2 bits (191), Expect = 6e-14
Identities = 301/1371 (21%), Positives = 433/1371 (31%), Gaps = 183/1371 (13%)
Query: 90 GPSPMLLPEGLSSQALSTEAPLPATLEPRIVMGEETCQALLSPRAARTALRDQEGGHASP 149
G + LL SS + PLP T G T + SP +A T GHA+P
Sbjct: 1260 GQATSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSAST-------GHATP 1312
Query: 150 DPPPEL--CSQGDLSVPSPPPDPDSFFTPPSTPTKTTYALLPACGPHGDARDSEAELRDE 207
P L S GD ++P P P S T +TP T A + G ++A
Sbjct: 1313 LPVTSLSSASTGD-TMPLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLHVTDASSAST 1371
Query: 208 LLDSP-PASPSGSYITADGDSWASSPSCSLSLLAPAEGLDFPSGWGLSPQGSMVDERELH 266
+P P + S T D ++P S + + G P +V +
Sbjct: 1372 GQATPLPVTSLSSVSTGD-----TTPLPVTSPSSASTGHATP---------LLVTDTSSA 1417
Query: 267 PAG--TPEPPSSESSLSADSSSSW-------GQEGHFFDLDFLANDPMIPAALLPFQGSL 317
G TP P + SS+S D ++S GH L +
Sbjct: 1418 STGHATPLPVTDASSVSTDHATSLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLLVTD 1477
Query: 318 IFQVEAVEVTPLSPEEEEEEAVADPDPGGDLAGEGEEDSTSASFLQSLSDLSITEGMDEA 377
V + TPL + P + + A+ L S S + G
Sbjct: 1478 TSSVSTGDTTPLPVTSTSSASTGHVTP-LHVTSPSSASTGHATPLPVTSLSSASTGDTMP 1536
Query: 378 FAFRDDTSAASSD------SDSASYAEADDERLYSGEPHAQATLLQDSVQKTEEESGGGA 431
+SA++ D +D++S + L P + +T + T+ S +
Sbjct: 1537 LPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLPVTSPSSASTGHTTPLPVTDTSS--AS 1594
Query: 432 KGLQAQDGTVSWAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQESTATVTPHTLQVA 491
KG D T P TS A L VT+ A ST TP + A
Sbjct: 1595 KG----DTT------PLPVTSPSSASTGHTTPL--PVTDTSSA----STGDTTPLPVTNA 1638
Query: 492 PGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQES---VTAEKLPT 548
L AT + ++ S A P P S G + VT T
Sbjct: 1639 SSLSTGHATPLHV--------TSPSSASTGHATPLPVTSTSSASTGHATPLPVTGLSSAT 1690
Query: 549 PQEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPL 608
+ T L + S + + L + S V+ P +T P ++ PL
Sbjct: 1691 TDDTTRLPVTDVSSASTGQATPLPVTS-LSSVSTGDTTPL----PVTSPSSASTGHASPL 1745
Query: 609 QDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQ 668
TD SSA A V+ T + PLP+ +S
Sbjct: 1746 LVTDASSASTGQATPLPVTD------TSSVSTAHATPLPVTGLSSASTDDTTRLPVTDVS 1799
Query: 669 QAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPL 728
A G +P +T P D + P A++ +T+P ++ L
Sbjct: 1800 SASTGQAIP--LPVTSPSSASTGDTTPLPVTDASSASTGDTTSLPVTIPSSASSGHTTSL 1857
Query: 729 QDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSS----APKPVAAAT 784
TD SS A + LV+ + + T PLP+ DT+ +S P V A+
Sbjct: 1858 PVTDASSVSTGHATSLLVTDASS------VSTGDTTPLPVTDTNSASTGDTTPLHVTDAS 1911
Query: 785 IVS------------QQAEEGLTLP--------QDSAMTPPLPLQDTDLSSAPK------ 818
VS A G T P S T PLP+ TD SS P
Sbjct: 1912 SVSTGHATSLPVTSLSSASTGDTTPLPVTSPSSASSGHTTPLPV--TDASSVPTGHATSL 1969
Query: 819 PVAAATIVSQQAEEGLTLPQDSAMTP--PLPLQDTDLSSAPKPVAAATPVSQQAEEGLTL 876
PV A+ VS L + S+++ PL TD SS A PV+ +
Sbjct: 1970 PVTDASSVSTGHATPLPVTDASSVSTGHATPLPVTDTSSVSTGQATPLPVTSLSS----- 2024
Query: 877 PQDSAMTPPLPLQDTDLSS----APKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDTG 932
+ T PLP+ DT +S P PV + + VS + T PLP+ T
Sbjct: 2025 -ASTGDTTPLPVTDTSSASTGQDTPLPVTSLSSVS------------TGDTTPLPV--TS 2069
Query: 933 PTSGPEPLAVATPQTLQAEAGCAPGTEPVATMAQQ-EVGEALGPRPAPEEKNAALPTVPE 991
P+S A T + T + T A G A + T P
Sbjct: 2070 PSSASTGHATPLLVTDASSVSTGHATSLLVTDASSVSTGHATALHVTDASSLSTGDTTPL 2129
Query: 992 PAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGRE 1051
P P A+ T D S A SLP + + A S P +
Sbjct: 2130 PVT-------SPSSASTGDTTPLPVTDTSSVSTGHATSLPVTDTSSA-STGHATSLPVTD 2181
Query: 1052 ACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAAC 1111
+ H D+ T G PL P SA G +
Sbjct: 2182 TSSASTGHATPLPVTDTSSAST--------GQATPLPVT-SPSSASTGHAIPLLVTDTSS 2232
Query: 1112 PEVSQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAP 1171
QA L +G +TP P ++ + S P +S+ +VS+ D
Sbjct: 2233 ASTGQATPLPVTSLSSASTGDTTPLPVTDASSVSTGHATSLPVTSLSSVSTGDTTPLPVT 2292
Query: 1172 APTSAPTSQ-QPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDRPLGPDPS 1230
+P+SA T P V S H TPL + A +TP+ P S
Sbjct: 2293 SPSSASTGHATPLHVTDASSASTGH------ATPLPVTSLSSASTGDTTPL-----PVTS 2341
Query: 1231 APGTLAGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQP 1290
G A P A + S G P V A++A +G T P
Sbjct: 2342 PSSASTGHATPLHVTDASSVSTGDTTPLPVTSSSSASSGHTTP-LPVTDASSASTGDTTP 2400
Query: 1291 LGTGPRVSLSPHSPLLSPKVASMDAKDLALQILPPCQVPPPSGPQSPAGPQGLSAPEQQE 1350
L S S P A LP V S + P ++
Sbjct: 2401 LPVTDTSSASTGHATHLPVTGLSSASTGDTTRLPVTNVSSASTGHATPLPVTSTSSASTG 2460
Query: 1351 DEDSLEEDSPRALGSGQHSDSHGESSAELDEQDILAPQTVQCPAQAPAGGS 1401
D L ++ +G H D + T + P +P+ S
Sbjct: 2461 DTTPLPGTDTSSVSTG-----HTTPLLVTDASSVSTGDTTRLPVTSPSSAS 2506
Score = 76.3 bits (186), Expect = 2e-13
Identities = 161/700 (23%), Positives = 238/700 (34%), Gaps = 149/700 (21%)
Query: 603 TPPLPLQDTDLSSA----PKPVAAATIVSQQAEEGLTLPQDSVM----TPPLPLQDTELS 654
T PLP DT S P V A+ VS L + S T PLP+ DT +
Sbjct: 2462 TTPLPGTDTSSVSTGHTTPLLVTDASSVSTGDTTRLPVTSPSSASTGHTTPLPVTDTPSA 2521
Query: 655 SA----PKPVAAATLVSQQAEEGLTLPQDSAMTP----PLPLQDTDLSSA----PKPVAA 702
S P PV A+ +S + L + S+ + LP+ DT +S P PV +
Sbjct: 2522 STGDTTPLPVTNASSLSTRHATSLHVTSPSSASTGHATSLPVTDTSAASTGHATPLPVTS 2581
Query: 703 ATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAM 762
+ S + T PLP+ DT +S + + A G
Sbjct: 2582 TSSAS------------TGDTTPLPVTDTYSASTGQATPLPVTDTSSASTG--------D 2621
Query: 763 TPPLPLQDTDLSSA----PKPVAAATIVSQQAEEGLTLPQDSAM----TPPLPLQDTD-- 812
T PLP+ DT +S P PV + VS L + S+ T PLP+ D
Sbjct: 2622 TTPLPVTDTSSASTGHATPLPVTNTSSVSTGHATPLHVTSPSSASTGHTTPLPVTDASSV 2681
Query: 813 ----LSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSS------------- 855
+S P A++ +T+P ++ PL TD SS
Sbjct: 2682 STGHATSLPVTDASSVFTGHATSLPVTIPSSASSGHTTPLPVTDASSVSTGHATSLPVTD 2741
Query: 856 ---------APKPVAAATPVSQQAEEGLTLPQDSAM----TPPLPLQDTDLSS----APK 898
P PV A+ VS L L S++ T PLP+ DT +S P
Sbjct: 2742 ASSVSTGHATPLPVTDASSVSTGHATPLPLTSLSSVSTGDTTPLPVTDTSSASTGQATPL 2801
Query: 899 PVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCA--- 955
PV + + VS + T PLP+ DT S ++ T A G A
Sbjct: 2802 PVTSLSSVS------------TGDTTPLPVTDTSSASTGHATSLPVTDTSSASTGHATPL 2849
Query: 956 PGTE------------PVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDP 1003
P T+ PV + +G A P +++ T + P
Sbjct: 2850 PDTDTSSASTGHATLLPVTDTSSASIGHATS---LPVTDTSSIST----GHATPLHVTSP 2902
Query: 1004 QPAAEA-GTPWAAQEDADSTLG-MEALSLPEPASGAGEEIAEALSRPGREACLEARAHTG 1061
A+ TP + + ++ G L + P+S + A P + + H
Sbjct: 2903 SSASTGHATPLPVTDTSSASTGHANPLHVTSPSSAS---TGHATPLPVTDTSSASTGHA- 2958
Query: 1062 DGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLS 1121
+P T + + G PL P SA G + QA L
Sbjct: 2959 ------TPLPVT-SLSSVSTGDTTPLPVT-SPSSASTGHTTPLPVTDTSSASTGQATALP 3010
Query: 1122 PAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQ- 1180
+G +TP P ++ A+ P +S+ +VS+ D +P+SA T
Sbjct: 3011 VTSTSSASTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHA 3070
Query: 1181 ----------------QPEPVLGLGSVEQPHEVPSVLGTP 1204
P PV L SV P + +P
Sbjct: 3071 TPLLVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSP 3110
Score = 75.1 bits (183), Expect = 5e-13
Identities = 233/1063 (21%), Positives = 344/1063 (32%), Gaps = 150/1063 (14%)
Query: 25 SCDAAAATTILGGDRREPCALTPGPSHLALTFLPSKPGARPQPEGASWDAGPGGA---PS 81
S AT +L D P H+ S P P + G A P
Sbjct: 3176 SVSTGHATPLLVTDASSASTGHATPLHVTSPSSASTGDTTPVPVTDTSSVSTGHATPLPV 3235
Query: 82 AWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIVMGEETCQALLSPRAARTALRD 141
G + L +SS + PLP T + G+ + SP +A T
Sbjct: 3236 TGLSSASTGDTTRLPVTDISSASTGQATPLPVTNTSSVSTGDTMPLPVTSPSSAST---- 3291
Query: 142 QEGGHASPDPPPELCSQGD-LSVPSPPPDPDSFFTPPSTPTKTTYALLPACGPHGDARDS 200
GHA+P P S + P P S T +TP T D +
Sbjct: 3292 ---GHATPLPVTSTSSASTGHATPVPVTSTSSASTGHTTPLPVT-----------DTSSA 3337
Query: 201 EAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLAPAEGLDFPSGWGLSPQGSMV 260
L + P+S S + T + SS S + P G S +P
Sbjct: 3338 STGDTTPLPVTSPSSASTGHTTPLHVTIPSSASTGDTSTLPVTGASSASTGHATPLPVTD 3397
Query: 261 DERELHPAGTPEPPSSESSLSADSSS-------SWGQEGHFFDLDFLANDPMIPAALLPF 313
TP P +S SS+S ++ S G L + + P
Sbjct: 3398 TSSVSTGHATPLPVTSLSSVSTGDTTPLPVTDASSASTGQATPLPVTSLSSVSTGDTTPL 3457
Query: 314 QGSLIFQVEAVEVTPLSPEEEEEEAVADPDPGGDLAGEGEEDSTSASFLQSLSDLSITEG 373
+ V TPL + + GD D++SAS Q+ + L +T
Sbjct: 3458 LVTDASSVSTGHATPLPVTDTSSAST------GDTTRLPVTDTSSASTGQA-TPLPVTSL 3510
Query: 374 MDEAFAFRDDTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSVQKTEEESGGGAKG 433
+ + D T +D+ S S A + + + V T S G A
Sbjct: 3511 --SSVSTGDTTPLLVTDASSVSTGHATPLPVTDTSSASTGDTTRLPVTDTSSASTGQATP 3568
Query: 434 LQAQDGTVSWAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQESTATVTPHTLQVAPG 493
L + S + P + +S VT A ST VTP +
Sbjct: 3569 LPVTIPSSSSSGHTTPLPVTSTSSVSTGHVTPLHVTSPSSA----STGHVTPLPVTSTSS 3624
Query: 494 LQVEVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEET 553
AT + + A S A P P + S + T + P P +T
Sbjct: 3625 ASTGHATPLLV--------TDASSVSTGHATPLPVTDASS------ASTGDTTPLPVTDT 3670
Query: 554 SLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDL 613
S AT +P + ++ + T PLP+ D
Sbjct: 3671 SSA----------------------STGQATPLPVTSLSSVS----TGDTTPLPVTDASS 3704
Query: 614 SSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEG 673
+S + G T+P + P + + P PV + S
Sbjct: 3705 ASTGHATPLPVTIPSSVSTGDTMP----LPVTSPSSASTGHATPLPVTGLSSAS------ 3754
Query: 674 LTLPQDSAMTPPLPLQDTDLSSA----PKPVAAATLVSQQAEEGLTLPQDSAMTP----P 725
+ T PLP+ DT +S P PV + S L + S+ + P
Sbjct: 3755 ------TGDTTPLPVTDTSSASTRHATPLPVTDTSSASTDDTTRLPVTDVSSASTGHATP 3808
Query: 726 LPLQDTDLSSA----PKPVAAATLVSQQAEEGLTLPQDSAMTP----PLPLQDTDLSSA- 776
LP+ T +S P PV + VS L + S+ + PLP+ DT S
Sbjct: 3809 LPVTSTSSASTGDTTPLPVTDTSSVSTGHATSLPVTSRSSASTGHATPLPVTDTSSVSTG 3868
Query: 777 ---PKPVAAATIVSQQAEEGLTLPQDSAMTP----PLPLQDTDLSSA----PKPVAAATI 825
P PV + + VS L + S+ + P+P+ T +S P PV A+
Sbjct: 3869 HATPLPVTSTSSVSTGHATPLPVTSPSSASTGHATPVPVTSTSSASTGDTTPLPVTNASS 3928
Query: 826 VSQQAEEGL--TLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMT 883
+S L T P ++ L TD SSA A P++ + + T
Sbjct: 3929 LSTGHATPLHVTSPSSASRGDTSTLPVTDASSASTGHATPLPLTSLSSVS------TGDT 3982
Query: 884 PPLPLQDTDLSSA------PKPVAAATPVSQQAEEGL--TLPQ--DSAMTAPLPLQDTGP 933
PLP+ TD SSA P PV + + VS L T+P S T LP+ D
Sbjct: 3983 TPLPV--TDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTIPSSASSGHTTSLPVTDASS 4040
Query: 934 TSGPEPLAVATPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAAL-PTVPEP 992
S + T A G PV + G A P P + +A+ P P
Sbjct: 4041 VSTGHGTPLPVTSTSSASTGDTTPL-PVTDTSSASTGHAT-PLPVTDTSSASTGHATPLP 4098
Query: 993 -AALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPA 1034
+L V P A + A+ +DS L ME + P+
Sbjct: 4099 VTSLSSVSTGHATPLAVSSATSASTVSSDSPLKMETPGMTTPS 4141
Score = 72.4 bits (176), Expect = 3e-12
Identities = 282/1295 (21%), Positives = 402/1295 (31%), Gaps = 176/1295 (13%)
Query: 18 PGPRTDLSCDAAAATTILGGDRREPCALTPG---PSHLALTFLPSKPGARPQPEGASWDA 74
P P TD S + TT L +L+ G P H+ S A P P ++ A
Sbjct: 1616 PLPVTDTSSASTGDTTPLPVTNAS--SLSTGHATPLHVTSPSSASTGHATPLPVTSTSSA 1673
Query: 75 GPGGA---PSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIVMGEETCQALLS 131
G A P + L +SS + PLP T + G+ T + S
Sbjct: 1674 STGHATPLPVTGLSSATTDDTTRLPVTDVSSASTGQATPLPVTSLSSVSTGDTTPLPVTS 1733
Query: 132 PRAARTALRDQEGGHASPDPPPELCSQG-DLSVPSPPPDPDSFFTPPSTPTKTTYALLPA 190
P +A T GHASP + S + P P D S T +TP LP
Sbjct: 1734 PSSAST-------GHASPLLVTDASSASTGQATPLPVTDTSSVSTAHATP-------LPV 1779
Query: 191 CGPHGDARDSEAEL---------RDELLDSPPASPSGSYITADGDSWASSPSCSLSLLAP 241
G + D L + + P SPS + + GD+ P S +
Sbjct: 1780 TGLSSASTDDTTRLPVTDVSSASTGQAIPLPVTSPSSA---STGDT-TPLPVTDASSAST 1835
Query: 242 AEGLDFPSGWGLSPQGSMVDERELHPAGTPEPPSSESSLSADSSSSWGQEGHFFDLDFLA 301
+ P S + A + + S L D+SS G L
Sbjct: 1836 GDTTSLPVTIPSSASSGHTTSLPVTDASSVSTGHATSLLVTDASSV--STGDTTPLPVTD 1893
Query: 302 NDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEEAVADPDP----GGDLAGEGEEDS- 356
+ P + V T L + D P A G
Sbjct: 1894 TNSASTGDTTPLHVTDASSVSTGHATSLPVTSLSSASTGDTTPLPVTSPSSASSGHTTPL 1953
Query: 357 --TSASFLQS--LSDLSITEGMDEAFAFRDDTSAASSDSDSASYAEADDERLYSGEPHAQ 412
T AS + + + L +T+ + + S S +A S Q
Sbjct: 1954 PVTDASSVPTGHATSLPVTDASSVSTGHATPLPVTDASSVSTGHATPLPVTDTSSVSTGQ 2013
Query: 413 ATLLQDSVQKTEEESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLSQRQELISEVTEEG 472
AT L V S G L D + + + P + +S VT
Sbjct: 2014 ATPL--PVTSLSSASTGDTTPLPVTDTSSASTGQDTPLPVTSLSSVSTGDTTPLPVTSPS 2071
Query: 473 LALGQESTATVTPHTLQVAPGLQVEVATR--VTPQAGEEETDSTAGQESAAMAMPQPSQE 530
A ST TP + A + AT VT + +TA + A ++
Sbjct: 2072 SA----STGHATPLLVTDASSVSTGHATSLLVTDASSVSTGHATALHVTDASSLSTGDTT 2127
Query: 531 GISEILGQESVTAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQA 590
+ + T + P P +TS ++ LP A+
Sbjct: 2128 PLPVTSPSSASTGDTTPLPVTDTS---------SVSTGHATSLPVTDTSSASTGHATSLP 2178
Query: 591 KEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLP------QDSVMTP 644
D + TP LP+ DT +S + A G +P +
Sbjct: 2179 VTDTSSASTGHATP-LPVTDTSSASTGQATPLPVTSPSSASTGHAIPLLVTDTSSASTGQ 2237
Query: 645 PLPLQDTELSSA------PKPVAAATLVSQQAEEGL------------------TLPQDS 680
PL T LSSA P PV A+ VS L T P +
Sbjct: 2238 ATPLPVTSLSSASTGDTTPLPVTDASSVSTGHATSLPVTSLSSVSTGDTTPLPVTSPSSA 2297
Query: 681 AMTPPLPLQDTDLSSA------PKPVAAATLVSQQAEEGL--TLPQDSAMTPPLPLQDTD 732
+ PL TD SSA P PV + + S L T P ++ PL TD
Sbjct: 2298 STGHATPLHVTDASSASTGHATPLPVTSLSSASTGDTTPLPVTSPSSASTGHATPLHVTD 2357
Query: 733 LSS------APKPVAAATLVSQQAEEGLTLPQDSAM----TPPLPLQDTD---------- 772
SS P PV +++ S L + S+ T PLP+ DT
Sbjct: 2358 ASSVSTGDTTPLPVTSSSSASSGHTTPLPVTDASSASTGDTTPLPVTDTSSASTGHATHL 2417
Query: 773 ----LSSA----PKPVAAATIVSQQAEEGLTLPQDSAM------TPPLPLQDTDLSS--- 815
LSSA + + S LP S T PLP DT S
Sbjct: 2418 PVTGLSSASTGDTTRLPVTNVSSASTGHATPLPVTSTSSASTGDTTPLPGTDTSSVSTGH 2477
Query: 816 -APKPVAAATIVSQQAEEGLTLPQDSAM----TPPLPLQDTDLSS----APKPVAAATPV 866
P V A+ VS L + S+ T PLP+ DT +S P PV A+ +
Sbjct: 2478 TTPLLVTDASSVSTGDTTRLPVTSPSSASTGHTTPLPVTDTPSASTGDTTPLPVTNASSL 2537
Query: 867 SQQAEEGL--TLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTA 924
S + L T P ++ L TD S+A A PV+ T + T
Sbjct: 2538 STRHATSLHVTSPSSASTGHATSLPVTDTSAASTGHATPLPVTS------TSSASTGDTT 2591
Query: 925 PLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNA 984
PLP+ DT S + + T A G PV + G A P P +
Sbjct: 2592 PLPVTDTYSASTGQATPLPVTDTSSASTGDTTPL-PVTDTSSASTGHA---TPLPVTNTS 2647
Query: 985 ALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPASGAGEEIAEA 1044
++ T + P A+ T DA S A SLP + A
Sbjct: 2648 SVST----GHATPLHVTSPSSASTGHTTPLPVTDASSVSTGHATSLP-VTDASSVFTGHA 2702
Query: 1045 LSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALGGAREVP 1104
S P + HT D+ T + ++ H + A V
Sbjct: 2703 TSLPVTIPSSASSGHTTPLPVTDASSVSTGHATSLPVTDASSVSTGHATPLPVTDASSVS 2762
Query: 1105 DAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLD 1164
P S + + +G +TP P ++ A+ P +S+ +VS+ D
Sbjct: 2763 TGHATPLPLTSLSSV---------STGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGD 2813
Query: 1165 RGCPDAPAPTSAPTSQQPE-PVLGLGSVEQPHEVP 1198
+SA T PV S H P
Sbjct: 2814 TTPLPVTDTSSASTGHATSLPVTDTSSASTGHATP 2848
Score = 70.1 bits (170), Expect = 2e-11
Identities = 189/799 (23%), Positives = 269/799 (33%), Gaps = 123/799 (15%)
Query: 605 PLPLQDTDLSSAPK--PVAAATIVSQQAEEGLTLPQDSVMTPP----LPLQDTELSSA-- 656
PLP+ DT S P+ + S ++ LP V + +PL T SSA
Sbjct: 1760 PLPVTDTSSVSTAHATPLPVTGLSSASTDDTTRLPVTDVSSASTGQAIPLPVTSPSSAST 1819
Query: 657 ----PKPVAAATLVSQQAEEGL--TLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQA 710
P PV A+ S L T+P ++ L TD SS A + LV+ +
Sbjct: 1820 GDTTPLPVTDASSASTGDTTSLPVTIPSSASSGHTTSLPVTDASSVSTGHATSLLVTDAS 1879
Query: 711 EEGLTLPQDSAMTPPLPLQDTDLSSA----PKPVAAATLVSQQAEEGLTLPQDSAM---- 762
+ T PLP+ DT+ +S P V A+ VS L + S+
Sbjct: 1880 SVS------TGDTTPLPVTDTNSASTGDTTPLHVTDASSVSTGHATSLPVTSLSSASTGD 1933
Query: 763 TPPLPLQDTDLSSA----PKPVAAATIVSQQAEEGLTLPQDSAMTP----PLPLQDTDLS 814
T PLP+ +S+ P PV A+ V L + S+++ PLP+ D
Sbjct: 1934 TTPLPVTSPSSASSGHTTPLPVTDASSVPTGHATSLPVTDASSVSTGHATPLPVTDASSV 1993
Query: 815 SA----PKPVAAATIVSQQAEEGLTLPQDSAM----TPPLPLQDTDLSSA----PKPVAA 862
S P PV + VS L + S+ T PLP+ DT +S P PV +
Sbjct: 1994 STGHATPLPVTDTSSVSTGQATPLPVTSLSSASTGDTTPLPVTDTSSASTGQDTPLPVTS 2053
Query: 863 ATPVSQQAEEGL--TLPQDSAMTPPLPLQDTDLSSAPKP------VAAATPVSQQAEEGL 914
+ VS L T P ++ PL TD SS V A+ VS L
Sbjct: 2054 LSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSVSTGHATSLLVTDASSVSTGHATAL 2113
Query: 915 TLPQDSAM--------------------TAPLPLQDTGPTSGPEPLAVATPQTLQAEAGC 954
+ S++ T PLP+ DT S ++ T A G
Sbjct: 2114 HVTDASSLSTGDTTPLPVTSPSSASTGDTTPLPVTDTSSVSTGHATSLPVTDTSSASTGH 2173
Query: 955 A---PGTE------------PVATMAQQEVGEALGPRPAPEEKNA----ALPTVPEPAAL 995
A P T+ PV + G+A P P +A A+P + +
Sbjct: 2174 ATSLPVTDTSSASTGHATPLPVTDTSSASTGQAT-PLPVTSPSSASTGHAIPLLVTDTSS 2232
Query: 996 DQVQQDDPQP------AAEAGTPWAAQEDADSTLGMEALSLPEPASGA---GEEIAEALS 1046
Q P P A+ T DA S A SLP + + G+ ++
Sbjct: 2233 ASTGQATPLPVTSLSSASTGDTTPLPVTDASSVSTGHATSLPVTSLSSVSTGDTTPLPVT 2292
Query: 1047 RPGREACLEAR-AHTGDGAKPDSPQKETLEV---ENQQEGGLKPLAQEHGPRSALGGARE 1102
P + A H D + + L V + G PL P SA G
Sbjct: 2293 SPSSASTGHATPLHVTDASSASTGHATPLPVTSLSSASTGDTTPLPVT-SPSSASTGHAT 2351
Query: 1103 VPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSS 1162
A+ L SG +TP P ++ A+ P + + S+
Sbjct: 2352 PLHVTDASSVSTGDTTPLPVTSSSSASSGHTTPLPVTDASSASTGDTTPLPVTDTSSAST 2411
Query: 1163 LDRGCPDAPAPTSAPTSQQPE-PVLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTPV 1221
+SA T PV + S H TPL + A +TP+
Sbjct: 2412 GHATHLPVTGLSSASTGDTTRLPVTNVSSASTGH------ATPLPVTSTSSASTGDTTPL 2465
Query: 1222 DRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAA 1281
G D S+ T G P L A + S G P V
Sbjct: 2466 P---GTDTSSVST--GHTTPLLVTDASSVSTGDTTRLPVTSPSSASTGHTTP-LPVTDTP 2519
Query: 1282 AAVSGTTQPLGTGPRVSLS 1300
+A +G T PL SLS
Sbjct: 2520 SASTGDTTPLPVTNASSLS 2538
Score = 40.4 bits (93), Expect = 0.014
Identities = 198/951 (20%), Positives = 304/951 (31%), Gaps = 161/951 (16%)
Query: 350 GEGEEDSTSA--SFLQSLSDLSITEGMDEAFAFRDDTSAASSDSDSASYAEADDERLYSG 407
G EE ST+ S S +SIT G + TS +S D+++ ++ R
Sbjct: 149 GNTEETSTAGTESSTPVTSAVSITAGQEGQSR---TTSWRTSIQDTSASSQNHWTRSTQT 205
Query: 408 EPHAQATLLQDSVQKTEEESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYL-----SQRQ 462
+Q + L T S + GTVS + +T+
Sbjct: 206 TRESQTSTLTHRTTSTPSFS----PSVHNVTGTVSQKTSPSGETATSSLCSVTNTSMMTS 261
Query: 463 ELISEVTEEGLALGQESTATVTPHTLQVAPGLQVEVATRVTPQAGEEETDS-TAGQESAA 521
E I+ T G LG + P T + P + T P+ T S T+ Q++ A
Sbjct: 262 EKITVTTSTGSTLGNPGETSSVPVTGSLMPVTSAALVT-FDPEGQSPATFSRTSTQDTTA 320
Query: 522 MAMPQPSQEGISEILGQESVTAEKLPTPQEETSLTLCPDSPQNLKEEGGLD---LPSGRK 578
+ +Q + + Q + P TS L SP G + PSG
Sbjct: 321 FSKNHQTQSVETTRVSQINTLNTLTPVT---TSTVL--SSPSGFNPSGTVSQETFPSGET 375
Query: 579 PVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQ 638
++ + V + L P T ++ ++ + +S + T+
Sbjct: 376 TTSSPSSV-----SNTFLVTSKVFRMPTSRDSTLGNTEETSLSVSGTISAITSKVSTIWW 430
Query: 639 DSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPK 698
++ T LS + P +T Q EG A T P + + S
Sbjct: 431 SDTLS-------TALSPSSLPPKISTAFHTQQSEG-------AETTGRPHERSSFSPG-- 474
Query: 699 PVAAATLVSQQA---EEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGL- 754
VSQ+ E T P + T+L S AA LV+ G
Sbjct: 475 -------VSQEIFTLHETTTWPSSFSSKGHTTWSQTELPSTSTG-AATRLVTGNPSTGTA 526
Query: 755 -TLPQDSAMTPPL--PLQDTDLSS----APKPVAAATIVSQQAEEGLTLPQDSAMTPPLP 807
T+P+ + + P + T SS PK A E G T ++ ++ P
Sbjct: 527 GTIPRVPSKVSAIGEPGEPTTYSSHSTTLPKTTGAGAQTQWTQETGTT--GEALLSSPSY 584
Query: 808 LQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAA---T 864
+ +A P ++ + +++ T P + T + T S P + T
Sbjct: 585 SVTQMIKTATSPSSSPMLDRHTSQQITTAPSTNHST----IHSTSTSPQESPAVSQRGHT 640
Query: 865 PVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQD----S 920
Q +E T S MT D + P ++ T E +PQD S
Sbjct: 641 QAPQTTQESQTTRSVSPMT--------DTKTVTTPGSSFTASGHSPSE--IVPQDAPTIS 690
Query: 921 AMT--APLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPA 978
A T AP P D T P A P + A G + GT T A +
Sbjct: 691 AATTFAPAPTGDGHTTQAPTTALQAAPSSHDATLGPSGGTSLSKTGALTLANSVVSTPGG 750
Query: 979 PEEK--NAALPTVPEPAAL-------------DQVQQDDPQPA----AEAGTPWAAQEDA 1019
PE + +A+ T P+ AA Q Q +P + AGT + A
Sbjct: 751 PEGQWTSASASTSPDTAAAMTHTHQAESTEASGQTQTSEPASSGSRTTSAGTATPSSSGA 810
Query: 1020 DSTL--GMEALSL----------PEPASGAGEEIAEALSRPGREACLEAR---------- 1057
T G E +S P S + E LS +
Sbjct: 811 SGTTPSGSEGISTSGETTRFSSNPSRDSHTTQSTTELLSASASHGAIPVSTGMASSIVPG 870
Query: 1058 ------AHTGDGAKPDSPQKETLEVENQQE-GGLKPLAQEHGPRSALGG--------ARE 1102
+ +P T + QE + +AQ R++ G A +
Sbjct: 871 TFHPTLSEASTAGRPTGQSSPTSPSASPQETAAISRMAQTQRTRTSRGSDTISLASQATD 930
Query: 1103 VPDAPPAACPEVSQARLLSPAREERGL----SGKS------TPEPTLPSAVATEASLDSC 1152
P P ++ L SP E L SGK+ + LP A+ AS
Sbjct: 931 TFSTVPPTPPSITSTGLTSPQTETHTLSPSGSGKTFTTALISNATPLPVTYASSASTGHT 990
Query: 1153 PESSVGAVSSLDRGCPDAPAPTSAPTS-----QQPEPVLGLGSVEQPHEVP 1198
V SS+ G P P ++P+S P PV S H P
Sbjct: 991 TPLHVTDASSVSTG-HATPLPVTSPSSVSTGHTTPLPVTDTSSESTGHVTP 1040
>gi|169205253 PREDICTED: hypothetical protein [Homo sapiens]
Length = 3859
Score = 87.0 bits (214), Expect = 1e-16
Identities = 202/866 (23%), Positives = 295/866 (34%), Gaps = 131/866 (15%)
Query: 572 DLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAE 631
D P +A + VP + +P A P +P+ D P A IVS
Sbjct: 604 DSPVLSVTLADSPAVPVTPADSPVVPVTPADGPVVPVASADSPFVPVTPADDPIVSVTPA 663
Query: 632 EGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDT 691
E +P +P +P+ + P A +V A +P A TP P+
Sbjct: 664 ESPAIPVTQADSPVVPVTSADRPVIPVTTADGRIVPVTAAGDPIVPVTPADTPGSPVTSA 723
Query: 692 D-----LSSAPKPVAAAT-----LVSQQAEEGLTLPQDSAMTPPLPLQDTD-----LSSA 736
D ++SA P T +V + +G P SA P +P+ D +SSA
Sbjct: 724 DGPVVPVTSADSPFVPVTPPDGPVVPVTSADGPVAPVSSADGPVVPVTSADGPVAPVSSA 783
Query: 737 PKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTL 796
PV T G +P SA +P +P+ D P A IV + +
Sbjct: 784 DGPVVPVTPAD---TNGPAVPVTSADSPFVPVIPADSPVVPVTPADDPIVPVTPADSSFV 840
Query: 797 PQDSAMTPPLPL----------QDTDLSSAPKPVAAATIVSQQAEEGLT--LPQDS---A 841
P SA +P +P+ TD+ P +V A+E + P DS
Sbjct: 841 PVISADSPFVPVIPADGPVVVDSSTDVLVVPVFPVNCILVPAFADETVVPLNPADSPVIP 900
Query: 842 MTPP----LPLQDTD-----LSSAPKPVAAATPVSQQAEEGLTLPQDSAMTPPLPLQDTD 892
+TPP +P+ TD ++SA PV TP A+ P +A P +P D
Sbjct: 901 VTPPDDLVVPVTPTDCPVAPVTSADCPVVPVTPADSPAD-----PVTAADGPVVPFTPAD 955
Query: 893 LSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEA 952
P A + VS +G +P SA + +P+ T +P+ TP AE+
Sbjct: 956 DPIVPVTPADSPVVSVTPADGPVVPVASADSPFVPV-----TPADDPIVSVTP----AES 1006
Query: 953 GCAPGTE---PVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDP-----Q 1004
P T+ PV + + RP A VP AA D + P
Sbjct: 1007 PAIPVTQADSPVVPVTSAD-------RPVSPVTTADGRIVPVTAAGDPIVPVTPADTPGS 1059
Query: 1005 PAAEAGTPWAAQEDADSTLGMEALSLPE----PASGAGEEIAEALSRPGREACLE----- 1055
P A P ADS ++ P+ P + A +A S G +
Sbjct: 1060 PVTSADGPVVPVTSADSP--FVPVTPPDGPVVPVTSADGPVAPVSSADGPVVPVTSADGP 1117
Query: 1056 -ARAHTGDG-AKPDSPQKETLEVENQQEGGLKPLAQEHGP--RSALGGAREVP------- 1104
A + DG P +P + + P+ P L + VP
Sbjct: 1118 VAPVSSADGPVVPVTPADSPFIPVTTADDPIVPVTPADSPVLSVTLADSPVVPVTPADSP 1177
Query: 1105 --DAPPAACPEV-----------------------SQARLLSPAREERG-LSGKSTPEPT 1138
PPA P V S L+ P G L +P
Sbjct: 1178 VIPVPPANGPVVPVSSADSPFVPVIPADGLVVLDSSTDVLVVPVSPTDGILVPDLADDPV 1237
Query: 1139 LPSAVATEASLDSCP-ESSVGAVSSLDRG-CPDAPAPTSAPTSQQPEPVLGLGSVEQPHE 1196
+ +A + P +S V V+S D P PA + PV+ + + + P
Sbjct: 1238 VSVTIADSPVIPVTPADSPVVPVTSADSPVVPVTPADSPVILVTPVGPVVSVTTADGPVV 1297
Query: 1197 VPSVLGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQE 1256
+ S +P++ + P TP D P+ P SA P +P P D
Sbjct: 1298 LVSTADSPVIPVTSADSPVVPVTPADGPVVPVTSADSPFV-PVTPADDPIVPVTPADSPI 1356
Query: 1257 DSVEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAK 1316
SV E P ++ + P + V P +A S G RV P +P P V A
Sbjct: 1357 VSVTPAESP-AIPVTPADSPVVPVTSADSPLIPLTTAGSRV--VPVTPTGDPIVPVTPAD 1413
Query: 1317 DLALQILPPCQVPPPSGPQSPAGPQG 1342
P V GP P P G
Sbjct: 1414 ------TPGSPVTSADGPVVPVTPAG 1433
Score = 85.9 bits (211), Expect = 3e-16
Identities = 190/878 (21%), Positives = 296/878 (33%), Gaps = 133/878 (15%)
Query: 572 DLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAE 631
D P +A + +VP + +P A P +P+ D P A +VS +
Sbjct: 334 DSPVLSVTLADSPVVPVTPADSPFVPAIPADGPVVPVTPADSPVVPVTPADGPVVSVASA 393
Query: 632 EGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDT 691
+ +P P + + + P A + L+ +G +P +A P +P+
Sbjct: 394 DSPFVPVTPADDPIVSVTPADSPVVPVTSADSPLIPVTTADGRVVPVTAAGDPIVPVTPA 453
Query: 692 D-----LSSAPKPVAAAT-----LVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVA 741
D ++SA PV T LV +G +P SA P P+ D P A
Sbjct: 454 DTPGSPVTSADGPVVPVTSADIPLVPVTPPDGPVVPVTSADGPVAPVSSADGPVVPVTPA 513
Query: 742 AATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSA 801
+ + + L +P A +P L + + + P A + IV G +P SA
Sbjct: 514 DSPFIPVTTADDLIVPVTPADSPVLSVTPAESPAIPVTPADSPIVPVTPANGPVVPVTSA 573
Query: 802 MTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVA 861
+P +P+ D P A + +V + L A +P +P+ D PV
Sbjct: 574 DSPFVPVIPADGPVVPVTPADSPVVPVTPADSPVLSVTLADSPAVPVTPAD-----SPVV 628
Query: 862 AATPVSQQAEEGLTLPQDSAMTPPLPLQDTD-------------------------LSSA 896
TP +G +P SA +P +P+ D ++SA
Sbjct: 629 PVTPA-----DGPVVPVASADSPFVPVTPADDPIVSVTPAESPAIPVTQADSPVVPVTSA 683
Query: 897 PKPVAAAT-------PVSQQAEEGLTLPQDSAMTAPLPLQDTGP----TSGPEPLAVATP 945
+PV T PV+ + + + +P+ D GP TS P TP
Sbjct: 684 DRPVIPVTTADGRIVPVTAAGDPIVPVTPADTPGSPVTSAD-GPVVPVTSADSPFVPVTP 742
Query: 946 ------QTLQAEAGCAPGTE---PVATMAQQE-----VGEALGPRPAPEEKNAALPTVPE 991
A+ AP + PV + + V A GP + P VP
Sbjct: 743 PDGPVVPVTSADGPVAPVSSADGPVVPVTSADGPVAPVSSADGPVVPVTPADTNGPAVPV 802
Query: 992 PAA----LDQVQQDDP-QPAAEAGTPWAAQEDADST----LGMEALSLPE-PASG--AGE 1039
+A + + D P P A P ADS+ + ++ +P PA G +
Sbjct: 803 TSADSPFVPVIPADSPVVPVTPADDPIVPVTPADSSFVPVISADSPFVPVIPADGPVVVD 862
Query: 1040 EIAEALSRPGREA-CLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALG 1098
+ L P C+ A + P +P + + + P+ P
Sbjct: 863 SSTDVLVVPVFPVNCILVPAFADETVVPLNPADSPVIPVTPPDDLVVPVTPTDCP----- 917
Query: 1099 GAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTP-----EPTLPSAVATEASLDSCP 1153
V A CP V SPA G P +P +P A + P
Sbjct: 918 ----VAPVTSADCPVVPVTPADSPADPVTAADGPVVPFTPADDPIVPVTPADSPVVSVTP 973
Query: 1154 -ESSVGAVSSLDRG-CPDAPA-----------PTSAPTSQQPEPVLGLGSVEQP------ 1194
+ V V+S D P PA + P +Q PV+ + S ++P
Sbjct: 974 ADGPVVPVASADSPFVPVTPADDPIVSVTPAESPAIPVTQADSPVVPVTSADRPVSPVTT 1033
Query: 1195 ---HEVP-SVLGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCL 1250
VP + G P++ G P T D P+ P SA PP P P
Sbjct: 1034 ADGRIVPVTAAGDPIVPVTPADTPGSPVTSADGPVVPVTSADSPFV-PVTPPDGPVVPVT 1092
Query: 1251 CQDPQEDSVEDEEPP-----GSLGLPPPQAGVQPAAAAVSGTTQPL-----GTGPRVSLS 1300
D V + P + G P + V+ P P V ++
Sbjct: 1093 SADGPVAPVSSADGPVVPVTSADGPVAPVSSADGPVVPVTPADSPFIPVTTADDPIVPVT 1152
Query: 1301 P-HSPLLSPKVASMDAKDLALQILPPCQVPPPSGPQSP 1337
P SP+LS +A + P VPP +GP P
Sbjct: 1153 PADSPVLSVTLADSPVVPVTPADSPVIPVPPANGPVVP 1190
Score = 85.9 bits (211), Expect = 3e-16
Identities = 161/790 (20%), Positives = 256/790 (32%), Gaps = 85/790 (10%)
Query: 572 DLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAE 631
D P A +VP + P +A P +P D P A + +VS
Sbjct: 915 DCPVAPVTSADCPVVPVTPADSPADPVTAADGPVVPFTPADDPIVPVTPADSPVVSVTPA 974
Query: 632 EGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDT 691
+G +P S +P +P+ + A P+ + T A +P A +P +P+
Sbjct: 975 DGPVVPVASADSPFVPV-----TPADDPIVSVTPAESPA-----IPVTQADSPVVPVTSA 1024
Query: 692 DLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTD-----LSSAPKPVAAAT-- 744
D +P A +V A +P A TP P+ D ++SA P T
Sbjct: 1025 DRPVSPVTTADGRIVPVTAAGDPIVPVTPADTPGSPVTSADGPVVPVTSADSPFVPVTPP 1084
Query: 745 ---LVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSA 801
+V + +G P SA P +P+ D AP A +V + +P +A
Sbjct: 1085 DGPVVPVTSADGPVAPVSSADGPVVPVTSADGPVAPVSSADGPVVPVTPADSPFIPVTTA 1144
Query: 802 MTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVA 861
P +P+ D +A + +V + +P A P +P+ D P A
Sbjct: 1145 DDPIVPVTPADSPVLSVTLADSPVVPVTPADSPVIPVPPANGPVVPVSSADSPFVPVIPA 1204
Query: 862 AATPVSQQAEEGLTL---PQDSAMTPPLPLQD-TDLSSAPKPVAAATPVSQQAEEGLTLP 917
V + + L + P D + P L ++ A PV TP + +P
Sbjct: 1205 DGLVVLDSSTDVLVVPVSPTDGILVPDLADDPVVSVTIADSPVIPVTPA-----DSPVVP 1259
Query: 918 QDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRP 977
SA + +P+ T P+ + TP A G + + A V P
Sbjct: 1260 VTSADSPVVPV-----TPADSPVILVTPVGPVVSVTTADGPVVLVSTADSPV------IP 1308
Query: 978 APEEKNAALPTVPEPAALDQVQQDDPQ--PAAEAGTPWAAQEDADSTLGMEALSLPEPAS 1035
+ +P P + V D P A P ADS + + PA
Sbjct: 1309 VTSADSPVVPVTPADGPVVPVTSADSPFVPVTPADDPIVPVTPADSPI-VSVTPAESPAI 1367
Query: 1036 GAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRS 1095
+ + ++ L G P +P + + + P+ GP
Sbjct: 1368 PVTPADSPVVPVTSADSPLIPLTTAGSRVVPVTPTGDPIVPVTPADTPGSPVTSADGP-- 1425
Query: 1096 ALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPES 1155
V PA P V +P G P T P+
Sbjct: 1426 -------VVPVTPAGDPIVPVTPADTPGSPVTSADGPVVPVTT--------------PDG 1464
Query: 1156 SVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLAKG 1215
+ VS PD P P + PV+ + + P + P++ +
Sbjct: 1465 PLVPVSP-----PDGPV---VPVTSADGPVVPVTPADSPFIPVTTADDPIVPVTPADSPV 1516
Query: 1216 QPSTPVDRPLGPDPSAPG-----TLAGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGL 1270
P TP D P+ P A G T A P+ P + D D + P G+
Sbjct: 1517 VPVTPADIPVVPVTPANGPVIHVTSADCPFVPVIPADGLVALDSSTDVLVVPVSPTD-GV 1575
Query: 1271 PPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLALQILPPCQVPP 1330
P P + + + P S L V + + D +P V P
Sbjct: 1576 LVPDLADDPVVSVTIADSPVIPVTPADSTVVPVTLADGPVVPVTSVD-----IPVVPVTP 1630
Query: 1331 PSGPQSPAGP 1340
+GP +P P
Sbjct: 1631 ANGPVAPVTP 1640
Score = 85.1 bits (209), Expect = 5e-16
Identities = 178/826 (21%), Positives = 270/826 (32%), Gaps = 118/826 (14%)
Query: 560 DSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTD-----LS 614
DSP D P A +VP + + L +P A P +P+ D +S
Sbjct: 1712 DSPVVPVTSADTDSPGSPVTSADGPVVPVTSADSLPVPVTPADGPVVPVTSADGPVAPVS 1771
Query: 615 SAPKPVAAAT-----IVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQ 669
SA PV T +V + T+P +P +P+ P A + V
Sbjct: 1772 SADGPVVPVTPADSPVVPVTTADDPTVPVTPADSPVVPVPPANGPIVPVTSADSPFVPVI 1831
Query: 670 AEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQ 729
+GL + S +P+ TD P +A +VS + +P A +P + +
Sbjct: 1832 PADGLVVLDSSTDVLVVPVSPTDGILVP-DLADDPVVSVTIADSPVIPVTPADSPVVLVT 1890
Query: 730 DTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQ 789
D P +V + +P P +P+ D P A + IVS
Sbjct: 1891 PADGPVVPVTSVDNPVVPVTPADNPVIPVTPVDDPVVPVTPADDPIVPVTSADSPIVSVT 1950
Query: 790 AEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQ 849
+ P A +P +P+ D P A +V +G +P A +P +P+
Sbjct: 1951 PADSPVFPVTPADSPVIPVASADSPLVPVTPADMVVVPVIPADGPVIPVTPAESPAIPVT 2010
Query: 850 DTD-----LSSAPKPVAAATPVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAP--KPVAA 902
TD ++SA PV PV+ + P DS + P P D + P PV
Sbjct: 2011 PTDSPVVPVTSADSPV---IPVTADSPFVPVTPADSPVIPVTPPDDLVVPVTPIDCPVVP 2067
Query: 903 ATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPVA 962
T V P S A P+ P GP P T P PV
Sbjct: 2068 VTLVD--------CPVVSVTPANSPVDPVTPADGP-----VVPVT--------PADSPVI 2106
Query: 963 TMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQ--PAAEAGTPWAAQEDAD 1020
P + +P P + + V D P A +P + AD
Sbjct: 2107 --------------PVTPADDLIVPVTPADSLIVSVTPADSPVVPVTPADSPVISVASAD 2152
Query: 1021 STL----GMEALSLP-EPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLE 1075
S + + + +P PA G + A S A P +P +
Sbjct: 2153 SPVVPVTPADTVVVPVTPADGPVIPVTPAES----------------PAIPVTPADSPVV 2196
Query: 1076 VENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTP 1135
+ + P+ P + PPA+ P V +P G P
Sbjct: 2197 PVTPADDPVVPVTPADSP---------IVPVPPASDPVVPVTPADTPGSPVASADGPVVP 2247
Query: 1136 EPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPH 1195
+ S + DS P V S A P P + +PV + + P
Sbjct: 2248 VTSADSPLVPVTPGDS-PVVPVTPADSPVFPVTSADGPV-FPVTLADDPVFPVTPADDPI 2305
Query: 1196 EVPSVLGTPLLQPPENLAKGQPSTPVDRPLGPDPSA-----PGTLAGAALPPLEPPAPCL 1250
S +P++ P TP + P+ P P A P T AG+ P+ P +
Sbjct: 2306 FPVSPADSPVV----------PVTPANIPVVPVPPANGSVVPVTSAGSPFVPIIPADGLV 2355
Query: 1251 CQDPQEDSVEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVS-LSPHSPLLSP- 1308
D D + P G+P P P + + + + P S + P +P P
Sbjct: 2356 VLDSSTDVLVVLVSPTD-GIPVPDLADDPVVSVTTSDSPVIPVTPTDSPVVPVAPADGPV 2414
Query: 1309 -KVASMDAKDLALQILPPCQVPPPSGPQSPAGP-QGLSAPEQQEDE 1352
V S+D+ P V P P P P L P D+
Sbjct: 2415 VPVTSVDS--------PVVPVTPADSPVIPVTPADSLVVPATPADD 2452
Score = 83.6 bits (205), Expect = 1e-15
Identities = 178/824 (21%), Positives = 276/824 (33%), Gaps = 113/824 (13%)
Query: 585 IVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTP 644
+VP + + +P D A P + + D P A +T+V +G +P SV P
Sbjct: 1566 VVPVSPTDGVLVP-DLADDPVVSVTIADSPVIPVTPADSTVVPVTLADGPVVPVTSVDIP 1624
Query: 645 PLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTD-----LSSAPKP 699
+P+ AP +VS +G +P SA P +P+ D ++ A P
Sbjct: 1625 VVPVTPANGPVAPVTPVDDPVVSVNPADGSVVPVTSADCPVVPVTPADGLVVPVTPADSP 1684
Query: 700 VAAAT-----LVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAAT---------- 744
+ T +V + + +P A +P +P+ D S PV +A
Sbjct: 1685 IVPVTPADSPVVLVTSADSPVIPVTPADSPVVPVTSADTDSPGSPVTSADGPVVPVTSAD 1744
Query: 745 --LVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAM 802
V +G +P SA P P+ D P A + +V + T+P A
Sbjct: 1745 SLPVPVTPADGPVVPVTSADGPVAPVSSADGPVVPVTPADSPVVPVTTADDPTVPVTPAD 1804
Query: 803 TPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTD---------- 852
+P +P+ + P A + V +GL + S +P+ TD
Sbjct: 1805 SPVVPVPPANGPIVPVTSADSPFVPVIPADGLVVLDSSTDVLVVPVSPTDGILVPDLADD 1864
Query: 853 ----LSSAPKPVAAATPVSQQA-----EEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAA 903
++ A PV TP +G +P S P +P+ D PV
Sbjct: 1865 PVVSVTIADSPVIPVTPADSPVVLVTPADGPVVPVTSVDNPVVPVTPAD-----NPVIPV 1919
Query: 904 TPVSQQAEEGLTLPQDSAM----TAPLPLQDTGPTSGPE-PLAVATPQTLQAEAGCAPGT 958
TPV P D + +A P+ P P P+ A + + +P
Sbjct: 1920 TPVDDPVVP--VTPADDPIVPVTSADSPIVSVTPADSPVFPVTPADSPVIPVASADSP-L 1976
Query: 959 EPV--ATMAQQEVGEALGP-RPAPEEKNAALPTVPEPAALDQV-QQDDPQPAAEAGTPWA 1014
PV A M V A GP P ++ A+P P + + V D P A +P+
Sbjct: 1977 VPVTPADMVVVPVIPADGPVIPVTPAESPAIPVTPTDSPVVPVTSADSPVIPVTADSPFV 2036
Query: 1015 AQEDADSTL----GMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQ 1070
ADS + + L +P + P +P
Sbjct: 2037 PVTPADSPVIPVTPPDDLVVPVTPIDCPVVPVTLVDCP---------------VVSVTPA 2081
Query: 1071 KETLEVENQQEGGLKPLAQEHGPRSALGGARE--VPDAP---------PAACPEVSQARL 1119
++ +G + P+ P + A + VP P PA P V
Sbjct: 2082 NSPVDPVTPADGPVVPVTPADSPVIPVTPADDLIVPVTPADSLIVSVTPADSPVVPVTPA 2141
Query: 1120 LSPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSA-PT 1178
SP +S S P +P A + P G V P PA + A P
Sbjct: 2142 DSPV-----ISVASADSPVVPVTPADTVVVPVTPAD--GPV------IPVTPAESPAIPV 2188
Query: 1179 SQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGA 1238
+ PV+ + + P + +P++ P P TP D P P SA G +
Sbjct: 2189 TPADSPVVPVTPADDPVVPVTPADSPIVPVPPASDPVVPVTPADTPGSPVASADGPV--- 2245
Query: 1239 ALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVS 1298
+P +P + P + V P S P A ++ T
Sbjct: 2246 -VPVTSADSPLVPVTPGDSPVVPVTPADSPVFPVTSADGPVFPVTLADDPVFPVTPADDP 2304
Query: 1299 LSPHSPLLSPKVASMDAKDLALQILPPCQVPPPSGPQSPAGPQG 1342
+ P SP SP V A +P VPP +G P G
Sbjct: 2305 IFPVSPADSPVVPVTPAN------IPVVPVPPANGSVVPVTSAG 2342
Score = 80.9 bits (198), Expect = 9e-15
Identities = 161/744 (21%), Positives = 253/744 (34%), Gaps = 87/744 (11%)
Query: 585 IVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTP 644
+VP +DL P A +P +P+ D P A +V + G +P +P
Sbjct: 88 VVPVTPADDLVFPVTPADSPVIPVTSADDPVVPITPADNPVVPVTSANGPVIPVTPADSP 147
Query: 645 PLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAAT 704
P+ + P A + + + P A +P P+ D ++ P A
Sbjct: 148 VFPVASADGPVVPVTPADSPVFPVTPADSPLFPVTPADSPLFPVTPADSAAIPVTPADGP 207
Query: 705 LVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTP 764
+V G +P A +P + + TD P A +V + +P SA +P
Sbjct: 208 VVHVTPANGTVVPVTPADSPVVTVASTDSPVVPVTPADDPIVPVTPADSSFVPVISADSP 267
Query: 765 PLPL----------QDTDLSSAPK-PV--------AAATIVSQQAEEGLTLPQDSAMTPP 805
+P+ TD+ P PV A TI L + +A P
Sbjct: 268 FVPVIPADGPVVVDSSTDVLVVPVFPVNCILVPAFADETIXXXXXXXSLVVSVTTADDPI 327
Query: 806 LPLQDTD-----LSSAPKPVAAAT-----IVSQQAEEGLTLPQDSAMTPPLPLQDTD--- 852
+P+ D ++ A PV T V +G +P A +P +P+ D
Sbjct: 328 VPVTPADSPVLSVTLADSPVVPVTPADSPFVPAIPADGPVVPVTPADSPVVPVTPADGPV 387
Query: 853 --LSSAPKPVAAATP-----VSQQAEEGLTLPQDSAMTPPLPLQDTD-----LSSAPKPV 900
++SA P TP VS + +P SA +P +P+ D +++A P+
Sbjct: 388 VSVASADSPFVPVTPADDPIVSVTPADSPVVPVTSADSPLIPVTTADGRVVPVTAAGDPI 447
Query: 901 AAATPVSQ-----QAEEGLTLPQDSAMTAPLPLQDTGPTSGP-EPLAVA---TPQTLQAE 951
TP + +G +P S A +PL P GP P+ A A+
Sbjct: 448 VPVTPADTPGSPVTSADGPVVPVTS---ADIPLVPVTPPDGPVVPVTSADGPVAPVSSAD 504
Query: 952 AGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDP-QPAAEAG 1010
P T + + L P + T E A+ D P P A
Sbjct: 505 GPVVPVTPADSPFIPVTTADDLIVPVTPADSPVLSVTPAESPAIPVTPADSPIVPVTPAN 564
Query: 1011 TPWAAQEDADSTLGMEALSLPE-PASGAGEEIAEALS-----RPGREACLEARAHTGDGA 1064
P ADS +P PA G + A S P L A
Sbjct: 565 GPVVPVTSADSPF------VPVIPADGPVVPVTPADSPVVPVTPADSPVLSVTL-ADSPA 617
Query: 1065 KPDSPQKETLEVENQQEGGLKPLAQEHGPRSALGGARE-VPDAPPAACPEVSQARLLSPA 1123
P +P + +G + P+A P + A + + PA P + + SP
Sbjct: 618 VPVTPADSPVVPVTPADGPVVPVASADSPFVPVTPADDPIVSVTPAESPAIPVTQADSPV 677
Query: 1124 REERGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPT-SAPTSQQP 1182
+ S P +P T A P ++ G D P PA T +P +
Sbjct: 678 -----VPVTSADRPVIP---VTTADGRIVPVTAAG-----DPIVPVTPADTPGSPVTSAD 724
Query: 1183 EPVLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLA--GAAL 1240
PV+ + S + P + P++ P + D P+ P SA G +A +A
Sbjct: 725 GPVVPVTSADSPFVPVTPPDGPVVPVTSADGPVAPVSSADGPVVPVTSADGPVAPVSSAD 784
Query: 1241 PPLEPPAPCLCQDPQEDSVEDEEP 1264
P+ P P P + P
Sbjct: 785 GPVVPVTPADTNGPAVPVTSADSP 808
Score = 74.3 bits (181), Expect = 8e-13
Identities = 188/890 (21%), Positives = 305/890 (34%), Gaps = 148/890 (16%)
Query: 542 TAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAAT-----IVPRQAKEDLT- 595
+ + L P T L PD L ++ + + G PV T ++P +D
Sbjct: 2679 STDVLVVPVFPTDGILVPD----LADDPVVPVTPGDDPVVPVTPGDDPVIPVTPADDGPF 2734
Query: 596 LPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSS 655
+P A+ P +P D S P + ++S ++GL +P D+V P +
Sbjct: 2735 VPVTPAVGPVVPDLTADDSVVPDSLTDDPVISVCPDDGLVVP-DTVRDSDGPEVSVYPVT 2793
Query: 656 APKPVAAAT---LVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEE 712
P +A +VS +GL + P + T+ P PV + S + +
Sbjct: 2794 GPVVTDSAADCPVVSVPLTDGLVVLCPPDEVPAVHDSVTNGLVVPDPVIDGPVFSNPSVD 2853
Query: 713 GLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEE-------------------- 752
G +P SA P +P PKP + +V+ +
Sbjct: 2854 GPIVPVASADNPGVPDPIRAFPVVPKPSTFSPVVTSTPADWIDVIVTPADCADVPVNPVN 2913
Query: 753 GLTLPQDSAMTPPLPLQDTD-----------LSSAPKPVAAATIVSQQAEEGLTLPQDSA 801
G +P S P +P+ TD + PV +V+ A +GL +P A
Sbjct: 2914 GPVVPDLSGDCPVVPVPPTDDIVVLNPPDVVFAVVSTPVTDGPVVTDPATDGLMVPVTPA 2973
Query: 802 MTPPLPLQ-----DTDLSSA--------------PKPVAAATIVSQQAEEGLTLPQDSAM 842
P+ D ++ A P P A +++VS +GL +P
Sbjct: 2974 NGSVAPVTLSEYPDVTVTPADGTVVSPTIGGPVVPDPSADSSVVSNPTTDGLIVPNPLLA 3033
Query: 843 TPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAA 902
P +P+ TD AP +A V+ +G + + P P + P
Sbjct: 3034 GPVVPVTPTDGPLAPVILADCPDVTVTPADGPVVCAFTTGGPVFPDPTAEGLVVSNPTVD 3093
Query: 903 ATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPVA 962
V+ + +GL SA A P P+ L L ++ T
Sbjct: 3094 DPVVTNPSTKGLV----SATPADCADVPVIPADCPDVLV-----NLVNDSVVPDFTADWT 3144
Query: 963 TMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDAD-- 1020
++ + + P P E +P P D AG P D
Sbjct: 3145 VVSVSPPDDLVAPDPPDEVPVVLVPITDGPVVPDLTTDGLVVSVTPAGAPVVPVFLTDCP 3204
Query: 1021 --STLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVEN 1078
+ ++ +P+P+S G +A++L G L D PDSP + +
Sbjct: 3205 DVTVTPADSPVVPDPSSD-GPVVADSLDDDG----LVPVTPADDSVVPDSPANGLVVPDP 3259
Query: 1079 QQEGGLKPLAQEHGPRSALGGAREVPDAPP-----AACPEVSQARL--LSPAREERG--- 1128
+G + P GP + A DAP A CP+V+ L + +RG
Sbjct: 3260 TTDGPVAPDPSVDGPVVPVTPA----DAPTVSVTLADCPDVTVTPPDGLVVSDSKRGGPV 3315
Query: 1129 LSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQ------- 1181
++G ST +P + + A + + P + V CPD P +P
Sbjct: 3316 VTGLSTNDPVITATPADFSDVTVTP-ADFEDVPVTPANCPDVPVNPESPVVSDLAVDFLV 3374
Query: 1182 --PEPVLGLGSVEQPHEVPSVLGTPLLQPPENLAKG-QPSTPV-DRPLGPDPSAPGTL-- 1235
P L +E P +VP V P+ ++ G S P+ + DPS G++
Sbjct: 3375 VPVVPSDDLVVLEPPDKVPVV--------PDPISNGLVVSDPITNNTAATDPSVDGSVVP 3426
Query: 1236 AGAALPPLEPPAPCLCQD----PQEDSVEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPL 1291
A P+ P C D P +DSV + A +
Sbjct: 3427 VSPADGPVAPVTLADCPDVTITPADDSVVSD---------------SKIRAEFEDVPVTI 3471
Query: 1292 GTGPRVSLSPHS-PLLSPKVASMDAKDLALQILPPCQVPPPSGPQSPAGP 1340
P V ++P S P++S DLA+ P +PPP +P P
Sbjct: 3472 ADCPNVPVNPKSGPVVS---------DLAVD-CPVVPIPPPDDLVAPEPP 3511
Score = 72.4 bits (176), Expect = 3e-12
Identities = 173/878 (19%), Positives = 295/878 (33%), Gaps = 120/878 (13%)
Query: 548 TPQEETSLTLCP-DSPQNLKEEGGLDLPSGRKPVAAATIV-----PRQAKEDLTLPQDSA 601
TP ++ + + P DSP + +P PV T P + + +P SA
Sbjct: 2199 TPADDPVVPVTPADSPI-------VPVPPASDPVVPVTPADTPGSPVASADGPVVPVTSA 2251
Query: 602 MTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLP---QDSVMTPPLPLQDT--ELSSA 656
+P +P+ D P A + + + +G P D + P P D +S A
Sbjct: 2252 DSPLVPVTPGDSPVVPVTPADSPVFPVTSADGPVFPVTLADDPVFPVTPADDPIFPVSPA 2311
Query: 657 PKPVAAAT-----LVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAE 711
PV T +V G +P SA +P +P+ D +V
Sbjct: 2312 DSPVVPVTPANIPVVPVPPANGSVVPVTSAGSPFVPIIPADGLVVLDSSTDVLVVLVSPT 2371
Query: 712 EGLTLPQ---------DSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAM 762
+G+ +P ++ +P +P+ TD P A +V + + +P A
Sbjct: 2372 DGIPVPDLADDPVVSVTTSDSPVIPVTPTDSPVVPVAPADGPVVPVTSVDSPVVPVTPAD 2431
Query: 763 TPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAA 822
+P +P+ D P A +VS +G +P +A P + + D P A
Sbjct: 2432 SPVIPVTPADSLVVPATPADDPVVSVTPADGPVVPVTTADIPVISVTSADSPVVPVTPAD 2491
Query: 823 ATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAM 882
+V + + + +P A P +P+ D P+ TP +++ D
Sbjct: 2492 GLVVPVTSADSVVVPATPADCPLVPVDPAD-----SPIVLFTPYDNPV---VSVTSDD-- 2541
Query: 883 TPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAV 942
+P P+ D S P A V +G +P A + +P+ TS P+
Sbjct: 2542 SPVFPVTPADSSVVPVTPAGVPVVPVTPGDGPVVPVTPADSLVVPV-----TSADSPVFP 2596
Query: 943 ATPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDD 1002
TP A++ P + + G++ +P + L T + + +
Sbjct: 2597 VTP----ADSPVFPVSPADDLVVPVTPGDSPVVPVSPADSPVVLVTPADGPVVPVTPANG 2652
Query: 1003 P-QPAAEAGTPWAAQEDADSTLGMEALS--LPEPASGAGEEIAEALSRPGREACLEARAH 1059
P P A +P+ AD + +++ + L P + L+ + +
Sbjct: 2653 PVVPVTSADSPFVPVIPADGLVVLDSSTDVLVVPVFPTDGILVPDLA----DDPVVPVTP 2708
Query: 1060 TGDGAKPDSPQKE-TLEVENQQEGGLKPLAQEHGP--RSALGGAREVPDAPP-----AAC 1111
D P +P + + V +G P+ GP VPD+ + C
Sbjct: 2709 GDDPVVPVTPGDDPVIPVTPADDGPFVPVTPAVGPVVPDLTADDSVVPDSLTDDPVISVC 2768
Query: 1112 PEVSQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAP 1171
P+ L R G + V T+++ D CP SV L CP
Sbjct: 2769 PDDG----LVVPDTVRDSDGPEVSVYPVTGPVVTDSAAD-CPVVSVPLTDGLVVLCPPDE 2823
Query: 1172 APT----------------SAPTSQQPE---PVLGLGSVEQPHEVPSVLGTPLLQPPENL 1212
P P P P++ + S + P + P++ P
Sbjct: 2824 VPAVHDSVTNGLVVPDPVIDGPVFSNPSVDGPIVPVASADNPGVPDPIRAFPVVPKPSTF 2883
Query: 1213 AKGQPSTPVD------RPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVEDEEP-- 1264
+ STP D P + G +P L P + P +D V P
Sbjct: 2884 SPVVTSTPADWIDVIVTPADCADVPVNPVNGPVVPDLSGDCPVVPVPPTDDIVVLNPPDV 2943
Query: 1265 ----------PGSLGLPPPQAGVQPAAAAVSGTTQP--LGTGPRVSLSPH-----SPLLS 1307
G + P G+ +G+ P L P V+++P SP +
Sbjct: 2944 VFAVVSTPVTDGPVVTDPATDGLMVPVTPANGSVAPVTLSEYPDVTVTPADGTVVSPTIG 3003
Query: 1308 PKVASMDAKDLALQILPPCQ---VPPP--SGPQSPAGP 1340
V + D ++ P VP P +GP P P
Sbjct: 3004 GPVVPDPSADSSVVSNPTTDGLIVPNPLLAGPVVPVTP 3041
Score = 67.4 bits (163), Expect = 1e-10
Identities = 190/873 (21%), Positives = 284/873 (32%), Gaps = 173/873 (19%)
Query: 579 PVAAAT--IVPRQAKEDLTLPQDSAMTPPLPLQDTD------------------------ 612
PV +A ++P + P SA P +P+ D
Sbjct: 130 PVTSANGPVIPVTPADSPVFPVASADGPVVPVTPADSPVFPVTPADSPLFPVTPADSPLF 189
Query: 613 ----LSSAPKPVAAA--TIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLV 666
SA PV A +V G +P +P + + T+ P A +V
Sbjct: 190 PVTPADSAAIPVTPADGPVVHVTPANGTVVPVTPADSPVVTVASTDSPVVPVTPADDPIV 249
Query: 667 SQQAEEGLTLPQDSAMTPPLPL----------QDTDLSSAPKPVAAATLVSQQAEE---- 712
+ +P SA +P +P+ TD+ P LV A+E
Sbjct: 250 PVTPADSSFVPVISADSPFVPVIPADGPVVVDSSTDVLVVPVFPVNCILVPAFADETIXX 309
Query: 713 -----GLTLPQDSAMTPPLPLQDTD-----LSSAPKPVAAAT-----LVSQQAEEGLTLP 757
L + +A P +P+ D ++ A PV T V +G +P
Sbjct: 310 XXXXXSLVVSVTTADDPIVPVTPADSPVLSVTLADSPVVPVTPADSPFVPAIPADGPVVP 369
Query: 758 QDSAMTPPLPLQDTD-----LSSAPKPVAAAT-----IVSQQAEEGLTLPQDSAMTPPLP 807
A +P +P+ D ++SA P T IVS + +P SA +P +P
Sbjct: 370 VTPADSPVVPVTPADGPVVSVASADSPFVPVTPADDPIVSVTPADSPVVPVTSADSPLIP 429
Query: 808 LQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAP--KPVAAATP 865
+ D P A IV + P SA P +P+ D+ P P P
Sbjct: 430 VTTADGRVVPVTAAGDPIVPVTPADTPGSPVTSADGPVVPVTSADIPLVPVTPPDGPVVP 489
Query: 866 VSQ--------QAEEGLTLPQDSAMTPPLPLQDTD-----LSSAPKPVAAATPVSQQAEE 912
V+ + +G +P A +P +P+ D ++ A PV + TP A
Sbjct: 490 VTSADGPVAPVSSADGPVVPVTPADSPFIPVTTADDLIVPVTPADSPVLSVTPAESPAIP 549
Query: 913 GLTLPQDSAMTAPLPLQDTGP----TSGPEPLAVATPQTLQAEAGCAPGTE------PVA 962
P DS + P GP TS P P A+ P T PV
Sbjct: 550 --VTPADSPIVPVTPA--NGPVVPVTSADSPFVPVIP----ADGPVVPVTPADSPVVPVT 601
Query: 963 TMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDP-QPAAEAGTPWAAQEDAD- 1020
+ L PA A P VP A D P P A A +P+ AD
Sbjct: 602 PADSPVLSVTLADSPAVPVTPADSPVVPVTPA------DGPVVPVASADSPFVPVTPADD 655
Query: 1021 ---STLGMEALSLP--------EPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSP 1069
S E+ ++P P + A + + GR + A GD P +P
Sbjct: 656 PIVSVTPAESPAIPVTQADSPVVPVTSADRPVIPVTTADGRIVPVTA---AGDPIVPVTP 712
Query: 1070 QKETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGL 1129
+G + P+ P VP PP P V P
Sbjct: 713 ADTPGSPVTSADGPVVPVTSADSP--------FVPVTPPDG-PVVPVTSADGPVAPVSSA 763
Query: 1130 SGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLG 1189
G P + VA +S D G V P PA T+ P + +
Sbjct: 764 DGPVVPVTSADGPVAPVSSAD-------GPV------VPVTPADTNG-------PAVPVT 803
Query: 1190 SVEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPC 1249
S + P +P++ P TP D P+ P A + +P + +P
Sbjct: 804 SADSPFVPVIPADSPVV----------PVTPADDPIVPVTPADSSF----VPVISADSPF 849
Query: 1250 LCQDPQEDSVEDEEPPGSLGLP--PPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLS 1307
+ P + V + L +P P + PA A + P + ++P L+
Sbjct: 850 VPVIPADGPVVVDSSTDVLVVPVFPVNCILVPAFADETVVPLNPADSPVIPVTPPDDLVV 909
Query: 1308 PKVASMDAKDLALQILPPCQVPPPSGPQSPAGP 1340
P V D +A C V P + SPA P
Sbjct: 910 P-VTPTDC-PVAPVTSADCPVVPVTPADSPADP 940
Score = 65.5 bits (158), Expect = 4e-10
Identities = 194/927 (20%), Positives = 310/927 (33%), Gaps = 112/927 (12%)
Query: 479 STATVTPHTLQVAPGLQVEVA--TRVTPQAGEEETDSTAGQESAAMAMPQPSQEGI---S 533
+ +V P TL P + V A T V+P G + S + P+ +G+ +
Sbjct: 2973 ANGSVAPVTLSEYPDVTVTPADGTVVSPTIGGPVVPDPSADSSV---VSNPTTDGLIVPN 3029
Query: 534 EILGQESVTAEKLPTPQEETSLTLCPDSPQNLKE--------EGGLDLPSGRKPVAAATI 585
+L V P L CPD + GG P P A +
Sbjct: 3030 PLLAGPVVPVTPTDGPLAPVILADCPDVTVTPADGPVVCAFTTGGPVFPD---PTAEGLV 3086
Query: 586 VPRQAKED--LTLPQDSAMTPPLPLQDTDLSSAPK--PVAAATIVSQQAEEGLTL----- 636
V +D +T P + P D+ P P +V+ T
Sbjct: 3087 VSNPTVDDPVVTNPSTKGLVSATPADCADVPVIPADCPDVLVNLVNDSVVPDFTADWTVV 3146
Query: 637 ---PQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDL 693
P D ++ P P E+ P+ +V +GL + A P +P+ TD
Sbjct: 3147 SVSPPDDLVAPDPP---DEVPVVLVPITDGPVVPDLTTDGLVVSVTPAGAPVVPVFLTDC 3203
Query: 694 SSAPKPVAAATLVSQQAEEGLTLPQ---DSAMTPPLPLQDTDLSSAPKPVAAATLVSQQA 750
A + +V + +G + D + P P D+ + +P A +V
Sbjct: 3204 PDVTVTPADSPVVPDPSSDGPVVADSLDDDGLVPVTPADDSVVPDSP---ANGLVVPDPT 3260
Query: 751 EEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPP---LP 807
+G P S P +P+ D + +A V+ +GL + P L
Sbjct: 3261 TDGPVAPDPSVDGPVVPVTPADAPTVSVTLADCPDVTVTPPDGLVVSDSKRGGPVVTGLS 3320
Query: 808 LQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQ-DTDLSSAPKPVAAATPV 866
D +++ P + T+ E+ +P A P +P+ ++ + S PV
Sbjct: 3321 TNDPVITATPADFSDVTVTPADFED---VPVTPANCPDVPVNPESPVVSDLAVDFLVVPV 3377
Query: 867 SQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSA--MTA 924
+ + P D P P+ + + S P+ T + + +G +P A A
Sbjct: 3378 VPSDDLVVLEPPDKVPVVPDPISNGLVVS--DPITNNTAATDPSVDGSVVPVSPADGPVA 3435
Query: 925 PLPLQDTGP-TSGPEPLAVATPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKN 983
P+ L D T P +V + ++AE P T +A V GP +
Sbjct: 3436 PVTLADCPDVTITPADDSVVSDSKIRAEFEDVPVT--IADCPNVPVNPKSGP--VVSDLA 3491
Query: 984 AALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPASGAG-EEIA 1042
P VP P D V P+P E P DS + + ++ AS + I
Sbjct: 3492 VDCPVVPIPPPDDLVA---PEPPDEV--PVVPDPITDSLVVSDPMTDGPVASDPSIDGIV 3546
Query: 1043 EALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALGGARE 1102
+ P L++ A PD+ + +G +
Sbjct: 3547 VPVVSPSGLLVLDSVADVS--ILPDTSADVPVTPVTLADGSV------------------ 3586
Query: 1103 VPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSS 1162
VPD+ P CP V + + G P P V + + D S+
Sbjct: 3587 VPDSAPD-CPVVPVLPTDGFVVLDLLVDGVVVPNPADVGPVVPDPTTDG--PDSIKDFPL 3643
Query: 1163 LDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSVLG---TPLLQPPENLAKGQPST 1219
+ PD P P ++ PV+ L S VP G L+ P +NL P
Sbjct: 3644 VPDPWPDCPV---VPVTRTDGPVV-LDSSADGVVVPVTPGDDSVALVTPTDNLVV--PDL 3697
Query: 1220 PVDRPLGPDPSAPG-----TLAGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQ 1274
D P+ PDPSA G +LA L P P + + D+ +P L P
Sbjct: 3698 TTDGPVVPDPSADGPVVLVSLADDLLVPNPPVKDTVVPNSVADNPVALDPVTDCPLVP-- 3755
Query: 1275 AGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLALQILPPCQVPPPSGP 1334
+P+A + T L GP V P P V + + L ++P P P
Sbjct: 3756 ---EPSANGLV-VTDSLDEGPVV---PDPSADDPVVLNPETNGL---VVPDISANGPVVP 3805
Query: 1335 QSPA-GPQGLSAPEQQEDEDSLEEDSP 1360
+P G P+ + D P
Sbjct: 3806 DTPTDGSDATVTPDDCSEVFVTATDGP 3832
Score = 50.1 bits (118), Expect = 2e-05
Identities = 79/362 (21%), Positives = 122/362 (33%), Gaps = 51/362 (14%)
Query: 547 PTPQEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPL 606
P P +E + P + + + D P P +VP + L + A L
Sbjct: 3508 PEPPDEVPVVPDPITDSLVVSDPMTDGPVASDPSIDGIVVPVVSPSGLLVLDSVADVSIL 3567
Query: 607 PLQDTDLSSAPKPVAAATIVSQQAEEGLT---LPQDSVMTPPLPLQDTELSSAPKPVAAA 663
P D+ P +A ++V A + LP D + L + + P P
Sbjct: 3568 PDTSADVPVTPVTLADGSVVPDSAPDCPVVPVLPTDGFVVLDLLVDGVVV---PNPADVG 3624
Query: 664 TLVSQQAEEGLTLPQDSAMTPP-------LPLQDTD----LSSAPKPVAAATLVSQQAEE 712
+V +G +D + P +P+ TD L S+ V +
Sbjct: 3625 PVVPDPTTDGPDSIKDFPLVPDPWPDCPVVPVTRTDGPVVLDSSADGVVVPVTPGDDSV- 3683
Query: 713 GLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQ---------DSAMT 763
L P D+ + P L TD P P A +V + L +P +S
Sbjct: 3684 ALVTPTDNLVVPDLT---TDGPVVPDPSADGPVVLVSLADDLLVPNPPVKDTVVPNSVAD 3740
Query: 764 PPLPLQD-TDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAA 822
P+ L TD P+P A +V+ +EG +P SA P
Sbjct: 3741 NPVALDPVTDCPLVPEPSANGLVVTDSLDEGPVVPDPSADDP------------------ 3782
Query: 823 ATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAM 882
+V GL +P SA P +P TD S A + V A +G + D +
Sbjct: 3783 --VVLNPETNGLVVPDISANGPVVPDTPTDGSDATVTPDDCSEVFVTATDGPDVVSDCPI 3840
Query: 883 TP 884
P
Sbjct: 3841 VP 3842
>gi|150418009 transforming, acidic coiled-coil containing protein 2
isoform a [Homo sapiens]
Length = 2948
Score = 86.7 bits (213), Expect = 2e-16
Identities = 314/1414 (22%), Positives = 471/1414 (33%), Gaps = 205/1414 (14%)
Query: 126 CQALLSPRAARTALRDQEGGHASPDPPPELCSQGDLSVPSPPPD-----PDSFFTPPSTP 180
C A S + L E DP +G L +PSPPP P S P
Sbjct: 59 CTASESSASLDPCLVSPEVTEPRKDPQGARGPEGSL-LPSPPPSQEREHPSSSMPFAECP 117
Query: 181 TKTTYALLPACGPHGDARDSEAELRDELLDSP----PASPSGSYITADGDSWASSPSCSL 236
+ A PA P D +++ R+ ++P A P+ + A+ PS
Sbjct: 118 PEGCLAS-PAAAPE-DGPQTQSPRREPAPNAPGDIAAAFPAERDSSTPYQEIAAVPSAGR 175
Query: 237 SLLAPAEG----LDFPSGWGLSPQGSMVDERELHPA---GTPEPPSSESSLSADSSSSWG 289
EG F SG SP S V RE A G + P S +++ +
Sbjct: 176 ERQPKEEGQKSSFSFSSGIDQSPGMSPVPLREPMKAPLCGEGDQPGGFESQEKEAAGGFP 235
Query: 290 QEGHFFDLDFLANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEEAVADPDPGGDLA 349
+ + P PAA QG+ E+ V SP + DP P
Sbjct: 236 PAESRQGVASVQVTPEAPAAAQ--QGT-----ESSAVLEKSPLKPMAPIPQDPAPRASDR 288
Query: 350 GEGEEDSTSASFLQSLSDLSITEGMDEAFAFRDDTSAASSDSDSASYAEADDERLYSGEP 409
G+ ++ L E + R ++ AA +A+ E+ + + + P
Sbjct: 289 ERGQGEAPPQYLTDDL------EFLRACHLPRSNSGAAPEAEVNAASQESCQQPVGAYLP 342
Query: 410 HAQATLLQDSVQKTEEESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLSQRQELISEVT 469
HA+ S E G G + L D V+ PQT RG +Q + +
Sbjct: 343 HAELPWGLPSPALVPEAGGSGKEALDTID------VQGHPQTGMRGTKPNQVVCVAAGGQ 396
Query: 470 EEGLALGQESTATVTP-------HTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAM 522
EG + +TP +L P Q+ +A P + E+ S AG +A
Sbjct: 397 PEGGLPVSPEPSLLTPTEEAHPASSLASFPAAQIPIAVE-EPGSSSRESVSKAGMPVSAD 455
Query: 523 AMPQPSQEGISEILGQESVTAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAA 582
A + G+ + Q S K P+ + P SPQ E + +P
Sbjct: 456 AAKEVVDAGLVGLERQVSDLGSKGEHPEGDPGEVPAP-SPQERGEHLNTEQSHEVQPGVP 514
Query: 583 ATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPK-PVAAATIVSQQ-----AEEGLTL 636
+P++ ++ Q A PPLP ++ + P P A + A+EG
Sbjct: 515 PPPLPKEQSHEV---QPGAPPPPLPKAPSESARGPPGPTDGAKVHEDSTSPAVAKEGSRS 571
Query: 637 PQDS------VMTPP-------LPLQDTE-LSSAPKPVAAATLVSQQAEEGLTLPQDSAM 682
P DS PP L +D++ SS P +S+ + + + S+
Sbjct: 572 PGDSPGGKEEAPEPPDGGDPGNLQGEDSQAFSSKRDPEVGKDELSKPSSDAESRDHPSSH 631
Query: 683 TPPLPLQD----TDLSSAPKPVAAAT-LVSQQAEEGLTLPQ--DSAMTPPLPLQDTDLSS 735
+ P + TD + A A+ L + EE LP D A P +P S
Sbjct: 632 SAQPPRKGGAGHTDGPHSQTAEADASGLPHKLGEEDPVLPPVPDGAGEPTVPEGAIWEGS 691
Query: 736 APKPVAAATLVSQQA----EEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAE 791
+P TL S++ E LTL + + PP P+ + APK + + +
Sbjct: 692 GLQPKCPDTLQSREGLGRMESFLTLESEKSDFPPTPVAEV----APKAQEGESTLEIRKM 747
Query: 792 -----EGLTLPQDSAMTPPLPLQDTDL-SSAPKPVAAATIVSQQAEEGLTLPQDSAMTPP 845
EGL D P + + P P + + L L QD P
Sbjct: 748 GSCDGEGLLTSPDQPRGPACDASRQEFHAGVPHPPQGENLAADLGLTALILDQDQQGIPS 807
Query: 846 LP-------------LQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTPP----LPL 888
P L ++ P T + +E P++ T P
Sbjct: 808 CPGEGWIRGAASEWPLLSSEKHLQPSQAQPETSIFDVLKEQAQPPENGKETSPSHPGFKD 867
Query: 889 QDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLP---LQDTGPTSGPEPLAVATP 945
Q D S PV + G S + + LP L DT PTS P + +
Sbjct: 868 QGADSSQIHVPVEPQEDNNLPTHGGQEQALGSELQSQLPKGTLSDT-PTSSPTDMVWESS 926
Query: 946 QTLQAEAGCAPGTEPVATMAQQEVGEALG--------PRPAPEEKNAAL----------- 986
T ++E AP + + + ++ A G P A K+ +L
Sbjct: 927 LTEESELS-APTRQKLPALGEKRPEGACGDGQSSRVSPPAADVLKDFSLAGNFSRKETCC 985
Query: 987 ----PTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPASGAGEEIA 1042
P + A D +++ A P A E AD + LS E ASG E
Sbjct: 986 TGQGPNKSQQALADALEEGSQHEEACQRHP-GASEAADGCSPLWGLSKREMASGNTGEAP 1044
Query: 1043 ----EALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALG 1098
++++ CL A A G P ET + QEG +P+
Sbjct: 1045 PCQPDSVALLDAVPCLPALAPASPGVTPTQDAPETEACDETQEGRQQPVPAPQQKMECWA 1104
Query: 1099 GAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTP----------EPTLP-SAVATEA 1147
+ A+ P + + A E G +G P E TL + TE
Sbjct: 1105 TSDAESPKLLASFPSAGEQGGEAGAAETGGSAGAGDPGKQQAPEKPGEATLSCGLLQTEH 1164
Query: 1148 SLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLG-----LGSVEQPHEVPSVLG 1202
L S E+S S+L C S + P LG VP
Sbjct: 1165 CLTSGEEAS---TSALRESCQAEHPMASCQDALLPARELGGIPRSTMDFSTHQAVPDPKE 1221
Query: 1203 TPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEP-PAPCLCQDPQ---EDS 1258
L PPE A P VD G A ++ P P +PC +P E++
Sbjct: 1222 LLLSGPPEVAAPDTPYLHVDSAAQRGAEDSGVKAVSSADPRAPGESPCPVGEPPLALENA 1281
Query: 1259 VEDEEPPGSLG--LPPPQAGVQ-PAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDA 1315
+ GSL L P AG + PA A SG SP + V SM
Sbjct: 1282 ASLKLFAGSLAPLLQPGAAGGEIPAVQASSG-------------SPKARTTEGPVDSMPC 1328
Query: 1316 KDLALQILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGES 1375
D + +L G Q+ + +AP +A G G D+ GE+
Sbjct: 1329 LD-RMPLL-------AKGKQATGEEKAATAPGA----------GAKASGEGMAGDAAGET 1370
Query: 1376 SAELDEQDILAPQTVQCPAQAPAGG---SEETIA 1406
++ + Q P Q +GG S E IA
Sbjct: 1371 EGSMERMG----EPSQDPKQGTSGGVDTSSEQIA 1400
Score = 53.9 bits (128), Expect = 1e-06
Identities = 328/1550 (21%), Positives = 524/1550 (33%), Gaps = 269/1550 (17%)
Query: 47 PGPSHLALTFLPSKPGARPQPEGASWDAGPGGAPSAWADPGEGGPSPMLLPEGLSSQALS 106
PGP+ A S A + S PGG A P G P + +G SQA S
Sbjct: 547 PGPTDGAKVHEDSTSPAVAKEGSRSPGDSPGGKEEAPEPPDGGDPGNL---QGEDSQAFS 603
Query: 107 TEAPLPATLEPRIVMGEETCQALLSPRAARTALRDQEGGHASPDPPPELCSQGDLSV--- 163
++ P + + ++ P ++ +A ++GG D P ++ D S
Sbjct: 604 SKRD-PEVGKDELSKPSSDAESRDHP-SSHSAQPPRKGGAGHTDGPHSQTAEADASGLPH 661
Query: 164 ------PSPPPDPDSFFTP--PSTPTKTTYALLPACGPHGDARD------SEAELRDELL 209
P PP PD P P L P C +R+ S L E
Sbjct: 662 KLGEEDPVLPPVPDGAGEPTVPEGAIWEGSGLQPKCPDTLQSREGLGRMESFLTLESEKS 721
Query: 210 DSPPASPSGSYITA-DGDSWASSPSCSLSLLAPAEG---LDFPSGWGLSPQGSMVD--ER 263
D PP + A +G+S + + + +G L P P+G D +
Sbjct: 722 DFPPTPVAEVAPKAQEGES-----TLEIRKMGSCDGEGLLTSPD----QPRGPACDASRQ 772
Query: 264 ELHPAGTPEPPSSESSLSADSSSSWGQEGHFFDLDFLANDPMIPAALLPFQGSLIFQVEA 323
E H AG P PP E+ L+AD G D D IP+ P +G + + A
Sbjct: 773 EFH-AGVPHPPQGEN-LAADL----GLTALILDQD----QQGIPSC--PGEGWI--RGAA 818
Query: 324 VEVTPLSPEEEEEEAVADPDPG-GDLAGEGEEDSTSASFLQSLSDLSITEGMDEAFAFRD 382
E LS E+ + + A P+ D+ E + + E F+D
Sbjct: 819 SEWPLLSSEKHLQPSQAQPETSIFDVLKEQAQPPENGK-----------ETSPSHPGFKD 867
Query: 383 DTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSVQKTEEESGGGAKGLQAQDGTVS 442
+ +S E ++ + G+ A + LQ + K GT+S
Sbjct: 868 QGADSSQIHVPVEPQEDNNLPTHGGQEQALGSELQSQLPK----------------GTLS 911
Query: 443 WAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQESTATVTPHTLQVAPGLQVEVATRV 502
++P + L++ EL + ++ ALG++ ++RV
Sbjct: 912 DTPTSSPTDMVWESSLTEESELSAPTRQKLPALGEKRPEGACGDGQ----------SSRV 961
Query: 503 TPQAGEEETD-STAGQESAAMAM-----PQPSQEGISEILGQESVTAEKLPTPQEETSLT 556
+P A + D S AG S P SQ+ +++ L + S E Q +
Sbjct: 962 SPPAADVLKDFSLAGNFSRKETCCTGQGPNKSQQALADALEEGSQHEEAC---QRHPGAS 1018
Query: 557 LCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSA 616
D L ++ SG A A D +P A+ P P
Sbjct: 1019 EAADGCSPLWGLSKREMASGNTGEAPPCQPDSVALLD-AVPCLPALAPASP------GVT 1071
Query: 617 PKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTL 676
P A T + +EG P V P ++ S A P A+ S + G
Sbjct: 1072 PTQDAPETEACDETQEGRQQP---VPAPQQKMECWATSDAESPKLLASFPSAGEQGG--- 1125
Query: 677 PQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSA 736
+ + A QQA E P ++ ++ L + L+S
Sbjct: 1126 -------------EAGAAETGGSAGAGDPGKQQAPEK---PGEATLSCGLLQTEHCLTSG 1169
Query: 737 PKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTL 796
+ +A S QAE + QD+ L +L P+ + + + +
Sbjct: 1170 EEASTSALRESCQAEHPMASCQDAL------LPARELGGIPR-----STMDFSTHQAVPD 1218
Query: 797 PQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSA 856
P++ ++ P ++++ P +Q+ E + S+ P P +
Sbjct: 1219 PKELLLSGP-----PEVAAPDTPYLHVDSAAQRGAEDSGVKAVSSADPRAP------GES 1267
Query: 857 PKPVAAATPVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAE--EGL 914
P PV P++ + L L S PL + P A+ S +A EG
Sbjct: 1268 PCPVGEP-PLALENAASLKLFAGSLA----PLLQPGAAGGEIPAVQASSGSPKARTTEG- 1321
Query: 915 TLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPVATMAQQEVGEALG 974
P DS +P D P LA T + +A APG A+ + G+A G
Sbjct: 1322 --PVDS-----MPCLDRMPL-----LAKGKQATGEEKAATAPGAGAKAS-GEGMAGDAAG 1368
Query: 975 PRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDAD----STLGMEALSL 1030
E+ P+ V Q A G P + A LG AL+
Sbjct: 1369 ETEGSMERMGEPSQDPKQGTSGGVDTSSEQIATLTGFPDFREHIAKIFEKPVLG--ALAT 1426
Query: 1031 PEPASGAGEE-IAEALSRP-GREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLA 1088
P +GAG + + L+RP G E L+ P P + L+VE +Q+
Sbjct: 1427 PGEKAGAGRSAVGKDLTRPLGPEKLLDGPPGVDVTLLPAPPAR--LQVEKKQQ------- 1477
Query: 1089 QEHGPRSALGGAREVPDAPPAACPEVSQARLLSPA--REERGLSGKSTPE------PTLP 1140
L G E+ A + + +LL PA ER L G + PTL
Sbjct: 1478 --------LAGEAEISHL---ALQDPASDKLLGPAGLTWERNLPGAGVGKEMAGVPPTLR 1526
Query: 1141 SAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVE---QPHEV 1197
E + P A S L+R + + +P + Q PV + + H
Sbjct: 1527 EDERPEGPGAAWPGLEGQAYSQLERSRQELASGLPSPAATQELPVERAAAFQVAPHSHGE 1586
Query: 1198 PSVLGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQED 1257
+V + ++ Q ++ D P G D PG A +P P + C PQ +
Sbjct: 1587 EAVAQDRIPSGKQH----QETSACDSPHGED--GPGDFAHTGVPGHVPRSTC-APSPQRE 1639
Query: 1258 SV---EDEEPPGSLGL------PPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSP 1308
+ E P +L P AG+ A+ + P V+ +P P
Sbjct: 1640 VLTVPEANSEPWTLDTLGGERRPGVTAGILEMRNALGNQSTPAPPTGEVADTPLEPGKVA 1699
Query: 1309 KVASMDAKDLALQ----------------------------ILP-PCQVPPPS----GPQ 1335
A D+ L +LP CQ P S G +
Sbjct: 1700 GAAGEAEGDITLSTAETQACASGDLPEAGTTRTFSVVAGDLVLPGSCQDPACSDKAPGME 1759
Query: 1336 SPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELDEQDI--LAPQTVQCP 1393
A G S Q+ ++ + P G G+ S E + + LAP+ +
Sbjct: 1760 GTAALHGDSPARPQQAKEQPGPERPIPAGDGKVCVSSPPEPDETHDPKLQHLAPEELHTD 1819
Query: 1394 AQAPAGGSEETIAKAKQSRSEKKARKAMSKLGLRQIQGVTRITIQKSKNILFVIAKPDVF 1453
++P G + K K A + M K+ + +G + + A P
Sbjct: 1820 RESPRPGPSMLPSVPK-----KDAPRVMDKVTSDETRGAEGTESSPVADDIIQPAAPADL 1874
Query: 1454 KSP--ASDTYV--VFGEAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAP 1499
+SP A+ +Y V G+ + ++Q + AAA PS +V SAP
Sbjct: 1875 ESPTLAASSYHGDVVGQVSTDLIAQSISPAAAHAGLPPSAAEHIVSPSAP 1924
Score = 43.9 bits (102), Expect = 0.001
Identities = 156/706 (22%), Positives = 252/706 (35%), Gaps = 99/706 (14%)
Query: 460 QRQELISEVTEEGLALGQESTATVTPHTLQVA-----PGLQVEVATRVTPQAGEEETDST 514
+R + + + E ALG +ST P T +VA PG +V AGE E D T
Sbjct: 1660 RRPGVTAGILEMRNALGNQSTPA--PPTGEVADTPLEPG-------KVAGAAGEAEGDIT 1710
Query: 515 AGQ-ESAAMAMPQPSQEGISEILG------------QESVTAEKLPTPQEETSLTL-CPD 560
E+ A A + G + Q+ ++K P + +L P
Sbjct: 1711 LSTAETQACASGDLPEAGTTRTFSVVAGDLVLPGSCQDPACSDKAPGMEGTAALHGDSPA 1770
Query: 561 SPQNLKEEGGLD--LPSGRKPVAAATI----------VPRQAKEDLTLPQDSAMTPPLPL 608
PQ KE+ G + +P+G V ++ + A E+L ++S P L
Sbjct: 1771 RPQQAKEQPGPERPIPAGDGKVCVSSPPEPDETHDPKLQHLAPEELHTDRESPRPGPSML 1830
Query: 609 QDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELS-SAPKPVAAATLVS 667
AP+ + T + EG T P+ D + +AP + + TL +
Sbjct: 1831 PSVPKKDAPRVMDKVTSDETRGAEG---------TESSPVADDIIQPAAPADLESPTLAA 1881
Query: 668 QQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLP 727
+ G + Q S + + P AA +VS A G + A TP P
Sbjct: 1882 S-SYHGDVVGQVSTDLIAQSISPAAAHAGLPPSAAEHIVSPSAPAG---DRVEASTPSCP 1937
Query: 728 LQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVS 787
DLS S +EE P+ T P+ P+ + + +
Sbjct: 1938 DPAKDLSR-----------SSDSEEAFETPES---TTPVKAPPAPPPPPPEVIPEPEVST 1983
Query: 788 QQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMT---P 844
Q E ++ P P D+ S +P + + S +E +
Sbjct: 1984 QPPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHS--FSAVFDEDKPIASSGTYNLDFD 2041
Query: 845 PLPLQDTDLSSAPKPVAAATP---VSQQAEEGLTLP-QDSAMTPPLPLQDTDLSSA---- 896
+ L DT + P+ A V+ + + ++P S ++ L LQ +D A
Sbjct: 2042 NIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSG 2101
Query: 897 -PKPVAAATPV-SQQAEEGLTLPQDSAMTAPLPLQDTGPTSGP-EPLAVATPQTLQAEAG 953
P+ VA A S + + + + P L+ T P E V Q E
Sbjct: 2102 NPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEES 2161
Query: 954 CAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAA--LDQVQQDDPQPAAEAG- 1010
P E +A+ + E + GP PA E+ P V AA LD + P A G
Sbjct: 2162 LVPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGG 2221
Query: 1011 ----TPWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKP 1066
+P ++ T EA + P+ G+E + A G LE ++ D +
Sbjct: 2222 RVQNSPPVGRKTLPLTTAPEAGEV-TPSDSGGQEDSPA---KGLSVRLEF-DYSEDKSSW 2276
Query: 1067 DSPQKETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACP 1112
D+ Q+ ++ G KP+A+ R + E D PA+ P
Sbjct: 2277 DNQQENP---PPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPP 2319
Score = 42.4 bits (98), Expect = 0.004
Identities = 225/1104 (20%), Positives = 368/1104 (33%), Gaps = 174/1104 (15%)
Query: 271 PEPPSSESSLSADSSSSWGQEGHFFDLDFLAND--PMIPAALLPFQGSLIFQVEAVEVTP 328
P P ++ +S W LD L + P + A +L + +L + TP
Sbjct: 1634 PSPQREVLTVPEANSEPW-------TLDTLGGERRPGVTAGILEMRNAL-----GNQSTP 1681
Query: 329 LSPEEEEEEAVADPDPGGDLAGEGEEDST-SASFLQSLSDLSITE-GMDEAFA-FRDDTS 385
P E + +P AGE E D T S + Q+ + + E G F+ D
Sbjct: 1682 APPTGEVADTPLEPGKVAGAAGEAEGDITLSTAETQACASGDLPEAGTTRTFSVVAGDLV 1741
Query: 386 AASSDSDSASYAEADDERLYSGEPHAQATLLQDSVQKTEE--ESGGGAKGLQAQDGTVSW 443
S D A +A A L DS + ++ E G + + A DG V
Sbjct: 1742 LPGSCQDPACSDKAPG-------MEGTAALHGDSPARPQQAKEQPGPERPIPAGDGKV-- 1792
Query: 444 AVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQESTATVTPHTLQVAPGLQVEVATRVT 503
V + P+ + + + E L +ES + P + + A RV
Sbjct: 1793 CVSSPPEPDE------THDPKLQHLAPEELHTDRESPRPGP----SMLPSVPKKDAPRVM 1842
Query: 504 PQAGEEETDSTAGQESAAMA-----------MPQPSQEGIS---EILGQESVTAEKLPTP 549
+ +ET G ES+ +A + P+ S +++GQ S
Sbjct: 1843 DKVTSDETRGAEGTESSPVADDIIQPAAPADLESPTLAASSYHGDVVGQVSTDLIAQSIS 1902
Query: 550 QEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQ 609
L P + +++ P+G + A+ P AK DL+ DS P
Sbjct: 1903 PAAAHAGLPPSAAEHIVSPSA---PAGDRVEASTPSCPDPAK-DLSRSSDSEEAFETPES 1958
Query: 610 DTDLSSAPKP-------VAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAA 662
T + + P P + + +Q E ++V P P D+ S +P +
Sbjct: 1959 TTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSH 2018
Query: 663 ATLVSQQAEEGLTLPQDSAMT---PPLPLQDTDLSSAPKPVAAAT---LVSQQAEEGLTL 716
+ S +E + + L DT + P+ A V+ + + ++
Sbjct: 2019 S--FSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSV 2076
Query: 717 P-QDSAMTPPLPLQDTDLSSA-----PKPVAAA--TLVSQQAEEGLTLPQDSAMTPPLPL 768
P S ++ L LQ +D A P+ VA A + + TL + PP L
Sbjct: 2077 PISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPP-SL 2135
Query: 769 QDTDLSSAPKPVAAATIVSQQAEEGLTLPQ----------DSAMT---PPLPLQDTDLSS 815
+ + P Q+ +E +P +SA T P L++T L
Sbjct: 2136 KKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEETPLEP 2195
Query: 816 APKPVAAATIVSQQAEEGLTLPQDSA----MTPPLPLQDTDLSSAPKPVAAATPVSQQAE 871
A P AA + S+ A EG+ P +PP+ + L++AP E
Sbjct: 2196 AVGPKAACPLDSESA-EGVVPPASGGGRVQNSPPVGRKTLPLTTAP-------------E 2241
Query: 872 EGLTLPQDSAMTPPLPLQDTDLS-SAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQD 930
G P DS P + + ++ +QQ T A +PL+
Sbjct: 2242 AGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRR 2301
Query: 931 TGPTSGPEPL--AVATPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPT 988
PE L A+P AE P + T ++ + P P + +
Sbjct: 2302 PKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTF---DIDKWDDPNFNPFSSTSKMQ- 2357
Query: 989 VPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPASG--AGEEIAEALS 1046
P Q DP E+ P+ S+ S PAS A + L+
Sbjct: 2358 -ESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLN 2416
Query: 1047 RPGREACLEARAHT--------------------GDGAKPDSPQKETLEVENQQEGGLKP 1086
+P ++ + T A P++P + V E L
Sbjct: 2417 KPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAV 2476
Query: 1087 LAQEHGPRSA-LGGAREVPDAPPAACPEVSQARLLSPAR----------EERGLSGKSTP 1135
Q+ + L ++ P V++ + SP E G S P
Sbjct: 2477 TNQKWTCMTVDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLP 2536
Query: 1136 -EPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQP 1194
+ P A D+ ES V S ++P P S + ++ E ++ + Q
Sbjct: 2537 QDDDAPKKQALYLMFDTSQES---PVKSSPVRMSESPTPCSGSSFEETEALVNTAAKNQ- 2592
Query: 1195 HEVPSVLG---TPLLQPPEN--------LAKGQPSTPVD--RPLGPDPSAPGTLAGAALP 1241
H VP L LQ PE + G PS ++ P G SA L+ A
Sbjct: 2593 HPVPRGLAPNQESHLQVPEKSSQKELEAMGLGTPSEAIEITAPEGSFASADALLSRLA-- 2650
Query: 1242 PLEPPAPCLCQDPQEDSVEDEEPP 1265
P + C D E + ++ PP
Sbjct: 2651 --HPVSLCGALDYLEPDLAEKNPP 2672
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 86.3 bits (212), Expect = 2e-16
Identities = 198/981 (20%), Positives = 339/981 (34%), Gaps = 122/981 (12%)
Query: 510 ETDSTAGQESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLTLCPDSPQNLKEEG 569
E D+ + ++ P + E E E+ TA+ P S L D P ++KE+
Sbjct: 66 EEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKA 125
Query: 570 GLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQ 629
+ K +P A S +P + +P A T+VS+
Sbjct: 126 KAETEKAGK---TGNSMPHPATGKTVANLLSGKSP---------RKSAEPSANTTLVSET 173
Query: 630 AEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQ 689
EEG ++P P + + S+ + ++++ + + P + +
Sbjct: 174 EEEG-SVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKE 232
Query: 690 DTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQ 749
+AP P V+ Q + G P A P + ++ S + A A SQ
Sbjct: 233 SPARKAAPAPGKVGD-VTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQV 291
Query: 750 AEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQ 809
L +A P + AP A A V+ Q + G P++ + +
Sbjct: 292 KASEKILQVRAASAPAKGTPGKGATPAPPGKAGA--VASQTKAGK--PEEDSES-----S 342
Query: 810 DTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPK----PVAAATP 865
+ S + + AA + Q G T +A P + AP P A
Sbjct: 343 SEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQ 402
Query: 866 VSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAP 925
++ E+ + ++S P Q AP+ AA+ P + +G AP
Sbjct: 403 AGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKG---------AAP 453
Query: 926 LPLQDTGPT-------------------SGPEPLAVATPQTLQAEA-GCAPGTEPVATMA 965
P + TGP S + A+A Q + G +P +P +TM
Sbjct: 454 APPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMG 513
Query: 966 QQEVGEALGPRPAPEEKNAALPT--VPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTL 1023
+G+ GP P P + A P+ V + + ++ +++ P A + +L
Sbjct: 514 MGPLGKGAGPVP-PGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSL 572
Query: 1024 G--MEALSLPEPASGAGEEIAEALSRPGREACL---EARAHTGDGAKPDSPQKETLEVEN 1078
G ++A PA G ++ + E + E+ + D A DS +
Sbjct: 573 GNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSA--DSEEAPAAMTAA 630
Query: 1079 QQEGGLKPLAQEHGPR--SALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPE 1136
Q + LK + P+ + A+ P P + SPA ++G T
Sbjct: 631 QAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKA-GTATSPAGSSPAVAG-GTQR 688
Query: 1137 PTLPSAVATEASLDSCPESS-----VGAVSSLDRGCP--DAPAPTSAPTSQQPEPVL--- 1186
P S+ + E+ DS E + VG S+ +G A P Q PVL
Sbjct: 689 PAEDSSSSEES--DSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGK 746
Query: 1187 --------------GLGSVEQPHEVPSVLGTPL---LQPPENLAKGQPSTPVDRPLGPDP 1229
S E+ + +P + AK P+
Sbjct: 747 TGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTI 806
Query: 1230 SAPGTLAGAALPP-------LEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAAA 1282
SAPG + AA ++PP ++PQ +V P +P V AA
Sbjct: 807 SAPGKVVTAAAQAKQRSPSKVKPPV----RNPQNSTVLARGPAS---VPSVGKAVATAAQ 859
Query: 1283 AVSGTTQPLGTGPRVSLSPH-SPLLSPKVASMDAKDLALQILPPCQVPPPSGPQSPAGPQ 1341
A +G + G+ S S + L+ S + + P + P +P G
Sbjct: 860 AQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKT 919
Query: 1342 GLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELDEQDILAPQTVQCPAQAPAGGS 1401
G SA + + +DS S + SDS GE+ A + ++ P + G
Sbjct: 920 GPSAAQAGKQDDSGS--------SSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGP 971
Query: 1402 EETIAKAKQSRSEKKARKAMS 1422
T A+A+ + + +KAR + S
Sbjct: 972 AATPAQAQAASTPRKARASES 992
Score = 76.6 bits (187), Expect = 2e-13
Identities = 248/1208 (20%), Positives = 411/1208 (34%), Gaps = 171/1208 (14%)
Query: 348 LAGEGEEDSTSASFLQSLSDLSITEGMDEAF---AFRDDTSAASSDSDSASYAEADDERL 404
L+G+ S S +L + EG AF A SA +DS S + + DE
Sbjct: 152 LSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETD 211
Query: 405 YSGEPHAQATLLQDSVQKTEEESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLSQRQEL 464
G+P + ++ S T+E A + G V+ V+ + A ++ E
Sbjct: 212 VEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRA---KKPEE 268
Query: 465 ISEVTEEGLALGQESTATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAM 524
SE +EEG +E+ A LQV A+ P G +T A A+
Sbjct: 269 ESESSEEGSESEEEAPAGTRSQVKASEKILQVRAAS--APAKGTPGKGATPAPPGKAGAV 326
Query: 525 PQPSQEGISEILGQESVTAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAAT 584
++ G E + S +E+ +EET P + L+ + SG+ A
Sbjct: 327 ASQTKAGKPEEDSESS--SEESSDSEEET-----PAAKALLQAKA-----SGKTSQVGAA 374
Query: 585 IVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTP 644
P AKE P+ A P P A ++ E+ + ++S
Sbjct: 375 SAP--AKES---PRKGAAPAP--------PGKTGPAVAKAQAGKREEDSQSSSEESDSEE 421
Query: 645 PLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAAT 704
P Q AP+ AA+ + +G P P + T P AA
Sbjct: 422 EAPAQAKPSGKAPQVRAASAPAKESPRKG---------AAPAPPRKTG------PAAAQV 466
Query: 705 LVSQQAEEGLTLPQDS-----AMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQD 759
V +Q E+ + ++S A+ Q L +P+ A+T+ +G
Sbjct: 467 QVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPP 526
Query: 760 SAMTPPLPL-------QDTDLS------SAPKPVAAATIVSQQAEEGLTLPQDSAMTPPL 806
+ P P +D++ S S+ V A +Q+ G L +P
Sbjct: 527 GKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSP-- 584
Query: 807 PLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPV 866
+ P A V +AE+ P D++ + D AP + AA
Sbjct: 585 -------AKGPPQKAGPVAVQVKAEK----PMDNSESSEESSDSADSEEAPAAMTAA--- 630
Query: 867 SQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTA-- 924
QA+ L +PQ A +T S+ PV T ++A + S A
Sbjct: 631 --QAKPALKIPQTKACPKK---TNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGG 685
Query: 925 -PLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKN 983
P +D+ + + T + + G A V +LG AP
Sbjct: 686 TQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPG 745
Query: 984 AALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDAD-STLGMEALSLPEPASGAGEEIA 1042
PTV + A + Q+D E+ + AA A T + + PA+
Sbjct: 746 KTGPTVTQVKA--EKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAK 803
Query: 1043 EALSRPGR--EACLEARAHTGDGAKPD--SPQKETL------EVENQQEGGLKPLAQEHG 1092
+S PG+ A +A+ + KP +PQ T+ V + + + G
Sbjct: 804 GTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTG 863
Query: 1093 PRSALGGAREVPDAPPAA--------CPEVSQAR-LLSPAREE-RGLSGKSTPEPTLPSA 1142
P G + E D+ A + Q R L+PA+E R + + P T PSA
Sbjct: 864 PEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSA 923
Query: 1143 VATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSVLG 1202
DS SS + D AP + ++Q +P L P+ P+
Sbjct: 924 AQAGKQDDS--------GSSSEESDSDGEAPAAVTSAQVIKPPL---IFVDPNRSPA--- 969
Query: 1203 TPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVEDE 1262
P A+ Q ++ + + +A + + + + P CL + + V
Sbjct: 970 ----GPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMP 1025
Query: 1263 EPPGSLGLPPPQAGVQPA--AAAVSGTTQPLGTGPRVSLSPHS-PLLSPKVASMDAKDLA 1319
+ AG + ++ +S + G +V + + P SP+ S+ AK
Sbjct: 1026 TAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKG-- 1083
Query: 1320 LQILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAEL 1379
P+ P Q APE +D + + S SG D G A+
Sbjct: 1084 --------TNKLRKPKLPEVQQATKAPESSDDSEDSSDSS-----SGSEEDGEGPQGAKS 1130
Query: 1380 DEQDILAPQTVQCPAQAPAGGSEETIAK--AKQSRSEKKARKAMSKLGLRQIQGVTRITI 1437
+ P ET+ + A +S + + S L G+T
Sbjct: 1131 AHTLV-----------GPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANS 1179
Query: 1438 QKSKNILFVIAKPDVFKSPASDTYVVF---GEAKIEDLSQQVHKAAAEKFKVPSEPSALV 1494
Q SK A P + SP+ + + + K E QQ + K S
Sbjct: 1180 QASK------ATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTT 1233
Query: 1495 PESAPRPR 1502
P+ + +P+
Sbjct: 1234 PQKSRKPK 1241
Score = 64.7 bits (156), Expect = 7e-10
Identities = 155/780 (19%), Positives = 273/780 (35%), Gaps = 87/780 (11%)
Query: 809 QDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAM-TPPLPLQDTDLSSAPKPVAAATPVS 867
+D L + V+ S+ +EE ++A TP L ++ + A P +
Sbjct: 67 EDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAK 126
Query: 868 QQAEE----GLTLPQDSA-MTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAM 922
+ E+ G ++P + T L + +P A T VS+ EEG ++P A
Sbjct: 127 AETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEG-SVPAFGAA 185
Query: 923 TAPLPLQDTGPTSGPEPLAVATPQT-LQAEAGCAPGTEPVATMAQQEV-GEALGPRPA-- 978
P + S E + ++ +T ++ + P ++++ +E P P
Sbjct: 186 AKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKV 245
Query: 979 ----PEEKNAALPTV-----PEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALS 1029
P+ K ALP PE + + + + A AGT + + ++ L + A S
Sbjct: 246 GDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTR-SQVKASEKILQVRAAS 304
Query: 1030 LPEPAS-GAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPL- 1087
P + G G A PG+ + ++ G + E ++ K L
Sbjct: 305 APAKGTPGKGATPAP----PGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL 360
Query: 1088 -AQEHGPRSALGGA----REVP-----DAPPAAC-PEVSQARLLSPAREERGLSGKSTPE 1136
A+ G S +G A +E P APP P V++A+ + + S +S E
Sbjct: 361 QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSE 420
Query: 1137 PTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHE 1196
P+ +S A S +G AP + P + Q + +G E+
Sbjct: 421 EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQ----VGKQEEDSR 476
Query: 1197 VPSVLGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQE 1256
S + A + +PLG P PA + P
Sbjct: 477 SSSEESDS-----DREALAAMNAAQVKPLGKSPQVK-------------PASTMGMGPLG 518
Query: 1257 DSVEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAK 1316
G+ +PP + G +A V + + S + VA K
Sbjct: 519 K--------GAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEK 570
Query: 1317 DLALQILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESS 1376
L + P GP AGP + ++ ++S E S + S ++ +
Sbjct: 571 SLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNS--ESSEESSDSADSEEAPAAMT 628
Query: 1377 AELDEQDILAPQTVQCPAQAPAGGSEETIAKAKQSRSEKKARKAMSKLGLR-QIQGVTRI 1435
A + + PQT CP + S + +++ +KA A S G + G T+
Sbjct: 629 AAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQR 688
Query: 1436 TIQKSKNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAAAEKFK---------- 1485
+ S + ++ + + V G+AK QV KAA+ K
Sbjct: 689 PAEDSSS-----SEESDSEEEKTGLAVTVGQAKSVGKGLQV-KAASVPVKGSLGQGTAPV 742
Query: 1486 VPSEPSALVPESAPRPRVRLECKEEEEEEEEEVDEAGLELRDIELVMAQANVSRAKAVRA 1545
+P + V + + E EEE + EE ++ A+AN + A+A A
Sbjct: 743 LPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSA 802
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 86.3 bits (212), Expect = 2e-16
Identities = 198/981 (20%), Positives = 339/981 (34%), Gaps = 122/981 (12%)
Query: 510 ETDSTAGQESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLTLCPDSPQNLKEEG 569
E D+ + ++ P + E E E+ TA+ P S L D P ++KE+
Sbjct: 66 EEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKA 125
Query: 570 GLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQ 629
+ K +P A S +P + +P A T+VS+
Sbjct: 126 KAETEKAGK---TGNSMPHPATGKTVANLLSGKSP---------RKSAEPSANTTLVSET 173
Query: 630 AEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQ 689
EEG ++P P + + S+ + ++++ + + P + +
Sbjct: 174 EEEG-SVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKE 232
Query: 690 DTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQ 749
+AP P V+ Q + G P A P + ++ S + A A SQ
Sbjct: 233 SPARKAAPAPGKVGD-VTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQV 291
Query: 750 AEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQ 809
L +A P + AP A A V+ Q + G P++ + +
Sbjct: 292 KASEKILQVRAASAPAKGTPGKGATPAPPGKAGA--VASQTKAGK--PEEDSES-----S 342
Query: 810 DTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPK----PVAAATP 865
+ S + + AA + Q G T +A P + AP P A
Sbjct: 343 SEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQ 402
Query: 866 VSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAP 925
++ E+ + ++S P Q AP+ AA+ P + +G AP
Sbjct: 403 AGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKG---------AAP 453
Query: 926 LPLQDTGPT-------------------SGPEPLAVATPQTLQAEA-GCAPGTEPVATMA 965
P + TGP S + A+A Q + G +P +P +TM
Sbjct: 454 APPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMG 513
Query: 966 QQEVGEALGPRPAPEEKNAALPT--VPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTL 1023
+G+ GP P P + A P+ V + + ++ +++ P A + +L
Sbjct: 514 MGPLGKGAGPVP-PGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSL 572
Query: 1024 G--MEALSLPEPASGAGEEIAEALSRPGREACL---EARAHTGDGAKPDSPQKETLEVEN 1078
G ++A PA G ++ + E + E+ + D A DS +
Sbjct: 573 GNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSA--DSEEAPAAMTAA 630
Query: 1079 QQEGGLKPLAQEHGPR--SALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPE 1136
Q + LK + P+ + A+ P P + SPA ++G T
Sbjct: 631 QAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKA-GTATSPAGSSPAVAG-GTQR 688
Query: 1137 PTLPSAVATEASLDSCPESS-----VGAVSSLDRGCP--DAPAPTSAPTSQQPEPVL--- 1186
P S+ + E+ DS E + VG S+ +G A P Q PVL
Sbjct: 689 PAEDSSSSEES--DSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGK 746
Query: 1187 --------------GLGSVEQPHEVPSVLGTPL---LQPPENLAKGQPSTPVDRPLGPDP 1229
S E+ + +P + AK P+
Sbjct: 747 TGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTI 806
Query: 1230 SAPGTLAGAALPP-------LEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAAA 1282
SAPG + AA ++PP ++PQ +V P +P V AA
Sbjct: 807 SAPGKVVTAAAQAKQRSPSKVKPPV----RNPQNSTVLARGPAS---VPSVGKAVATAAQ 859
Query: 1283 AVSGTTQPLGTGPRVSLSPH-SPLLSPKVASMDAKDLALQILPPCQVPPPSGPQSPAGPQ 1341
A +G + G+ S S + L+ S + + P + P +P G
Sbjct: 860 AQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKT 919
Query: 1342 GLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELDEQDILAPQTVQCPAQAPAGGS 1401
G SA + + +DS S + SDS GE+ A + ++ P + G
Sbjct: 920 GPSAAQAGKQDDSGS--------SSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGP 971
Query: 1402 EETIAKAKQSRSEKKARKAMS 1422
T A+A+ + + +KAR + S
Sbjct: 972 AATPAQAQAASTPRKARASES 992
Score = 84.3 bits (207), Expect = 8e-16
Identities = 268/1253 (21%), Positives = 418/1253 (33%), Gaps = 224/1253 (17%)
Query: 348 LAGEGEEDSTSASFLQSLSDLSITEGMDEAF---AFRDDTSAASSDSDSASYAEADDERL 404
L+G+ S S +L + EG AF A SA +DS S + + DE
Sbjct: 152 LSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETD 211
Query: 405 YSGEPHAQATLLQDSVQKTEEESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLSQRQEL 464
G+P + ++ S T+E A + G V+ V+ + A + +
Sbjct: 212 VEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESE 271
Query: 465 ISE---VTEEGLALGQESTATVTPHTLQV------APGLQVEVATRVTP----------Q 505
SE +EE G S + LQV A G + AT P +
Sbjct: 272 SSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTK 331
Query: 506 AGEEETDSTAGQESA---------------AMAMPQPSQEGISEILGQESVTAEKLPTPQ 550
AG+ E DS + E + A A + SQ G + +ES P P
Sbjct: 332 AGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPP 391
Query: 551 EETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQD 610
+T + +E D S + + P QAK PQ A + P +
Sbjct: 392 GKTGPAVAKAQAGKREE----DSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAK-ES 446
Query: 611 TDLSSAPK------PVAAATIVSQQAEEGLTLPQDS-----VMTPPLPLQDTELSSAPKP 659
+AP P AA V +Q E+ + ++S + Q L +P+
Sbjct: 447 PRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQV 506
Query: 660 VAAATLVSQQAEEGLTLPQDSAMTPPLPL-------QDTDLS------SAPKPVAAATLV 706
A+T+ +G + P P +D++ S S+ V A
Sbjct: 507 KPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAP 566
Query: 707 SQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPL 766
+Q+ G L +P + P A V +AE+ P D++ +
Sbjct: 567 AQEKSLGNILQAKPTSSP---------AKGPPQKAGPVAVQVKAEK----PMDNSESSEE 613
Query: 767 PLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIV 826
D AP + AA QA+ L +PQ T P + +SA VA +
Sbjct: 614 SSDSADSEEAPAAMTAA-----QAKPALKIPQ----TKACPKKTNTTASA--KVAPVRVG 662
Query: 827 SQQAEEGLTLPQDSAMTPPL------PLQDTDLS----SAPKPVAAATPVSQQAEEGLTL 876
+Q + T + +P + P +D+ S S + A V Q G L
Sbjct: 663 TQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGL 722
Query: 877 PQDSAMTPPLPL--QDTDLSSAPKPVAAATPV---SQQAEEGLTLPQDSAMTAPLPLQDT 931
+A P Q T K T V Q+ E DS A P Q
Sbjct: 723 QVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQ-- 780
Query: 932 GPTSGPEPLAVATPQTLQAEAG----CAPGTEPVATMAQQEVGEALGPRPAPEEKN---- 983
TS + A A P +A + APG A ++ + P +N
Sbjct: 781 VKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVL 840
Query: 984 ----AALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPASGAGE 1039
A++P+V + A Q P+ ++G +++E++DS E L+ +P SG
Sbjct: 841 ARGPASVPSVGKAVATAAQAQTGPE--EDSG---SSEEESDSEEEAETLAQVKP-SGKTH 894
Query: 1040 EIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALGG 1099
+I AL+ P +E+ GA P P G P A + G + G
Sbjct: 895 QIRAALA-PAKES-------PRKGAAPTPP------------GKTGPSAAQAGKQDDSGS 934
Query: 1100 AREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGA 1159
+ E D+ A V+ A+++ P + P P+A +A S P + +
Sbjct: 935 SSEESDSDGEAPAAVTSAQVIKPPL----IFVDPNRSPAGPAATPAQAQAASTPRKARAS 990
Query: 1160 VSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPST 1219
S+ ++ P +Q P + V P P + P ++A S
Sbjct: 991 ESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMP------TAHPRIAPKASMAGASSSK 1044
Query: 1220 PVDR-PLGPDPSAPGTLAG----AALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQ 1274
R G P T A+LP + L Q E PP
Sbjct: 1045 ESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASE-------------AQPPV 1091
Query: 1275 AGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLALQILPPCQVPPPSGP 1334
A QP+ SG +GT P SP+ S+ AK P
Sbjct: 1092 ARTQPS----SGVDSAVGT---------LPATSPQSTSVQAKG----------TNKLRKP 1128
Query: 1335 QSPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELDEQDILAPQTVQCPA 1394
+ P Q APE +D + + S SG D G A+
Sbjct: 1129 KLPEVQQATKAPESSDDSEDSSDSS-----SGSEEDGEGPQGAK------------SAHT 1171
Query: 1395 QAPAGGSEETIAK--AKQSRSEKKARKAMSKLGLRQIQGVTRITIQKSKNILFVIAKPDV 1452
P ET+ + A +S + + S L G+T Q SK A P +
Sbjct: 1172 LGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASK------ATPKL 1225
Query: 1453 FKSPASDTYVVF---GEAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPRPR 1502
SP+ + + + K E QQ + K S P+ + +P+
Sbjct: 1226 DSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPK 1278
Score = 64.7 bits (156), Expect = 7e-10
Identities = 155/780 (19%), Positives = 273/780 (35%), Gaps = 87/780 (11%)
Query: 809 QDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAM-TPPLPLQDTDLSSAPKPVAAATPVS 867
+D L + V+ S+ +EE ++A TP L ++ + A P +
Sbjct: 67 EDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAK 126
Query: 868 QQAEE----GLTLPQDSA-MTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAM 922
+ E+ G ++P + T L + +P A T VS+ EEG ++P A
Sbjct: 127 AETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEG-SVPAFGAA 185
Query: 923 TAPLPLQDTGPTSGPEPLAVATPQT-LQAEAGCAPGTEPVATMAQQEV-GEALGPRPA-- 978
P + S E + ++ +T ++ + P ++++ +E P P
Sbjct: 186 AKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKV 245
Query: 979 ----PEEKNAALPTV-----PEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALS 1029
P+ K ALP PE + + + + A AGT + + ++ L + A S
Sbjct: 246 GDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTR-SQVKASEKILQVRAAS 304
Query: 1030 LPEPAS-GAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPL- 1087
P + G G A PG+ + ++ G + E ++ K L
Sbjct: 305 APAKGTPGKGATPAP----PGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL 360
Query: 1088 -AQEHGPRSALGGA----REVP-----DAPPAAC-PEVSQARLLSPAREERGLSGKSTPE 1136
A+ G S +G A +E P APP P V++A+ + + S +S E
Sbjct: 361 QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSE 420
Query: 1137 PTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHE 1196
P+ +S A S +G AP + P + Q + +G E+
Sbjct: 421 EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQ----VGKQEEDSR 476
Query: 1197 VPSVLGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQE 1256
S + A + +PLG P PA + P
Sbjct: 477 SSSEESDS-----DREALAAMNAAQVKPLGKSPQVK-------------PASTMGMGPLG 518
Query: 1257 DSVEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAK 1316
G+ +PP + G +A V + + S + VA K
Sbjct: 519 K--------GAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEK 570
Query: 1317 DLALQILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESS 1376
L + P GP AGP + ++ ++S E S + S ++ +
Sbjct: 571 SLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNS--ESSEESSDSADSEEAPAAMT 628
Query: 1377 AELDEQDILAPQTVQCPAQAPAGGSEETIAKAKQSRSEKKARKAMSKLGLRQ-IQGVTRI 1435
A + + PQT CP + S + +++ +KA A S G + G T+
Sbjct: 629 AAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQR 688
Query: 1436 TIQKSKNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAAAEKFK---------- 1485
+ S + ++ + + V G+AK QV KAA+ K
Sbjct: 689 PAEDSSS-----SEESDSEEEKTGLAVTVGQAKSVGKGLQV-KAASVPVKGSLGQGTAPV 742
Query: 1486 VPSEPSALVPESAPRPRVRLECKEEEEEEEEEVDEAGLELRDIELVMAQANVSRAKAVRA 1545
+P + V + + E EEE + EE ++ A+AN + A+A A
Sbjct: 743 LPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSA 802
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a [Homo
sapiens]
Length = 1450
Score = 86.3 bits (212), Expect = 2e-16
Identities = 198/981 (20%), Positives = 339/981 (34%), Gaps = 122/981 (12%)
Query: 510 ETDSTAGQESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLTLCPDSPQNLKEEG 569
E D+ + ++ P + E E E+ TA+ P S L D P ++KE+
Sbjct: 66 EEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKA 125
Query: 570 GLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQ 629
+ K +P A S +P + +P A T+VS+
Sbjct: 126 KAETEKAGK---TGNSMPHPATGKTVANLLSGKSP---------RKSAEPSANTTLVSET 173
Query: 630 AEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQ 689
EEG ++P P + + S+ + ++++ + + P + +
Sbjct: 174 EEEG-SVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKE 232
Query: 690 DTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQ 749
+AP P V+ Q + G P A P + ++ S + A A SQ
Sbjct: 233 SPARKAAPAPGKVGD-VTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQV 291
Query: 750 AEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQ 809
L +A P + AP A A V+ Q + G P++ + +
Sbjct: 292 KASEKILQVRAASAPAKGTPGKGATPAPPGKAGA--VASQTKAGK--PEEDSES-----S 342
Query: 810 DTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPK----PVAAATP 865
+ S + + AA + Q G T +A P + AP P A
Sbjct: 343 SEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQ 402
Query: 866 VSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAP 925
++ E+ + ++S P Q AP+ AA+ P + +G AP
Sbjct: 403 AGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKG---------AAP 453
Query: 926 LPLQDTGPT-------------------SGPEPLAVATPQTLQAEA-GCAPGTEPVATMA 965
P + TGP S + A+A Q + G +P +P +TM
Sbjct: 454 APPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMG 513
Query: 966 QQEVGEALGPRPAPEEKNAALPT--VPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTL 1023
+G+ GP P P + A P+ V + + ++ +++ P A + +L
Sbjct: 514 MGPLGKGAGPVP-PGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSL 572
Query: 1024 G--MEALSLPEPASGAGEEIAEALSRPGREACL---EARAHTGDGAKPDSPQKETLEVEN 1078
G ++A PA G ++ + E + E+ + D A DS +
Sbjct: 573 GNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSA--DSEEAPAAMTAA 630
Query: 1079 QQEGGLKPLAQEHGPR--SALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPE 1136
Q + LK + P+ + A+ P P + SPA ++G T
Sbjct: 631 QAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKA-GTATSPAGSSPAVAG-GTQR 688
Query: 1137 PTLPSAVATEASLDSCPESS-----VGAVSSLDRGCP--DAPAPTSAPTSQQPEPVL--- 1186
P S+ + E+ DS E + VG S+ +G A P Q PVL
Sbjct: 689 PAEDSSSSEES--DSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGK 746
Query: 1187 --------------GLGSVEQPHEVPSVLGTPL---LQPPENLAKGQPSTPVDRPLGPDP 1229
S E+ + +P + AK P+
Sbjct: 747 TGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTI 806
Query: 1230 SAPGTLAGAALPP-------LEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAAA 1282
SAPG + AA ++PP ++PQ +V P +P V AA
Sbjct: 807 SAPGKVVTAAAQAKQRSPSKVKPPV----RNPQNSTVLARGPAS---VPSVGKAVATAAQ 859
Query: 1283 AVSGTTQPLGTGPRVSLSPH-SPLLSPKVASMDAKDLALQILPPCQVPPPSGPQSPAGPQ 1341
A +G + G+ S S + L+ S + + P + P +P G
Sbjct: 860 AQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKT 919
Query: 1342 GLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELDEQDILAPQTVQCPAQAPAGGS 1401
G SA + + +DS S + SDS GE+ A + ++ P + G
Sbjct: 920 GPSAAQAGKQDDSGS--------SSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGP 971
Query: 1402 EETIAKAKQSRSEKKARKAMS 1422
T A+A+ + + +KAR + S
Sbjct: 972 AATPAQAQAASTPRKARASES 992
Score = 77.0 bits (188), Expect = 1e-13
Identities = 248/1208 (20%), Positives = 410/1208 (33%), Gaps = 172/1208 (14%)
Query: 348 LAGEGEEDSTSASFLQSLSDLSITEGMDEAF---AFRDDTSAASSDSDSASYAEADDERL 404
L+G+ S S +L + EG AF A SA +DS S + + DE
Sbjct: 152 LSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETD 211
Query: 405 YSGEPHAQATLLQDSVQKTEEESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLSQRQEL 464
G+P + ++ S T+E A + G V+ V+ + A ++ E
Sbjct: 212 VEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRA---KKPEE 268
Query: 465 ISEVTEEGLALGQESTATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAM 524
SE +EEG +E+ A LQV A+ P G +T A A+
Sbjct: 269 ESESSEEGSESEEEAPAGTRSQVKASEKILQVRAAS--APAKGTPGKGATPAPPGKAGAV 326
Query: 525 PQPSQEGISEILGQESVTAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAAT 584
++ G E + S +E+ +EET P + L+ + SG+ A
Sbjct: 327 ASQTKAGKPEEDSESS--SEESSDSEEET-----PAAKALLQAKA-----SGKTSQVGAA 374
Query: 585 IVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTP 644
P AKE P+ A P P A ++ E+ + ++S
Sbjct: 375 SAP--AKES---PRKGAAPAP--------PGKTGPAVAKAQAGKREEDSQSSSEESDSEE 421
Query: 645 PLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAAT 704
P Q AP+ AA+ + +G P P + T P AA
Sbjct: 422 EAPAQAKPSGKAPQVRAASAPAKESPRKG---------AAPAPPRKTG------PAAAQV 466
Query: 705 LVSQQAEEGLTLPQDS-----AMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQD 759
V +Q E+ + ++S A+ Q L +P+ A+T+ +G
Sbjct: 467 QVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPP 526
Query: 760 SAMTPPLPL-------QDTDLS------SAPKPVAAATIVSQQAEEGLTLPQDSAMTPPL 806
+ P P +D++ S S+ V A +Q+ G L +P
Sbjct: 527 GKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSP-- 584
Query: 807 PLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPV 866
+ P A V +AE+ P D++ + D AP + AA
Sbjct: 585 -------AKGPPQKAGPVAVQVKAEK----PMDNSESSEESSDSADSEEAPAAMTAA--- 630
Query: 867 SQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTA-- 924
QA+ L +PQ A +T S+ PV T ++A + S A
Sbjct: 631 --QAKPALKIPQTKACPKK---TNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGG 685
Query: 925 -PLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKN 983
P +D+ + + T + + G A V +LG AP
Sbjct: 686 TQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPG 745
Query: 984 AALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDAD-STLGMEALSLPEPASGAGEEIA 1042
PTV + A + Q+D E+ + AA A T + + PA+
Sbjct: 746 KTGPTVTQVKA--EKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAK 803
Query: 1043 EALSRPGR--EACLEARAHTGDGAKPD--SPQKETL------EVENQQEGGLKPLAQEHG 1092
+S PG+ A +A+ + KP +PQ T+ V + + + G
Sbjct: 804 GTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTG 863
Query: 1093 PRSALGGAREVPDAPPAA--------CPEVSQAR-LLSPAREE-RGLSGKSTPEPTLPSA 1142
P G + E D+ A + Q R L+PA+E R + + P T PSA
Sbjct: 864 PEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSA 923
Query: 1143 VATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSVLG 1202
DS SS + D AP + ++Q +P L P+ P+
Sbjct: 924 AQAGKQDDS--------GSSSEESDSDGEAPAAVTSAQVIKPPL---IFVDPNRSPA--- 969
Query: 1203 TPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVEDE 1262
P A+ Q ++ + + +A + + + + P CL + + V
Sbjct: 970 ----GPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMP 1025
Query: 1263 EPPGSLGLPPPQAGVQPA--AAAVSGTTQPLGTGPRVSLSPHS-PLLSPKVASMDAKDLA 1319
+ AG + ++ +S + G +V + + P SP+ S+ AK
Sbjct: 1026 TAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKG-- 1083
Query: 1320 LQILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAEL 1379
P+ P Q APE +D + + S SG D G A+
Sbjct: 1084 --------TNKLRKPKLPEVQQATKAPESSDDSEDSSDSS-----SGSEEDGEGPQGAK- 1129
Query: 1380 DEQDILAPQTVQCPAQAPAGGSEETIAK--AKQSRSEKKARKAMSKLGLRQIQGVTRITI 1437
P ET+ + A +S + + S L G+T
Sbjct: 1130 -----------SAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANS 1178
Query: 1438 QKSKNILFVIAKPDVFKSPASDTYVVF---GEAKIEDLSQQVHKAAAEKFKVPSEPSALV 1494
Q SK A P + SP+ + + + K E QQ + K S
Sbjct: 1179 QASK------ATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTT 1232
Query: 1495 PESAPRPR 1502
P+ + +P+
Sbjct: 1233 PQKSRKPK 1240
Score = 64.7 bits (156), Expect = 7e-10
Identities = 155/780 (19%), Positives = 273/780 (35%), Gaps = 87/780 (11%)
Query: 809 QDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAM-TPPLPLQDTDLSSAPKPVAAATPVS 867
+D L + V+ S+ +EE ++A TP L ++ + A P +
Sbjct: 67 EDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAK 126
Query: 868 QQAEE----GLTLPQDSA-MTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAM 922
+ E+ G ++P + T L + +P A T VS+ EEG ++P A
Sbjct: 127 AETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEG-SVPAFGAA 185
Query: 923 TAPLPLQDTGPTSGPEPLAVATPQT-LQAEAGCAPGTEPVATMAQQEV-GEALGPRPA-- 978
P + S E + ++ +T ++ + P ++++ +E P P
Sbjct: 186 AKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKV 245
Query: 979 ----PEEKNAALPTV-----PEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALS 1029
P+ K ALP PE + + + + A AGT + + ++ L + A S
Sbjct: 246 GDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTR-SQVKASEKILQVRAAS 304
Query: 1030 LPEPAS-GAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPL- 1087
P + G G A PG+ + ++ G + E ++ K L
Sbjct: 305 APAKGTPGKGATPAP----PGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL 360
Query: 1088 -AQEHGPRSALGGA----REVP-----DAPPAAC-PEVSQARLLSPAREERGLSGKSTPE 1136
A+ G S +G A +E P APP P V++A+ + + S +S E
Sbjct: 361 QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSE 420
Query: 1137 PTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHE 1196
P+ +S A S +G AP + P + Q + +G E+
Sbjct: 421 EEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQ----VGKQEEDSR 476
Query: 1197 VPSVLGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQE 1256
S + A + +PLG P PA + P
Sbjct: 477 SSSEESDS-----DREALAAMNAAQVKPLGKSPQVK-------------PASTMGMGPLG 518
Query: 1257 DSVEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAK 1316
G+ +PP + G +A V + + S + VA K
Sbjct: 519 K--------GAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEK 570
Query: 1317 DLALQILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESS 1376
L + P GP AGP + ++ ++S E S + S ++ +
Sbjct: 571 SLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNS--ESSEESSDSADSEEAPAAMT 628
Query: 1377 AELDEQDILAPQTVQCPAQAPAGGSEETIAKAKQSRSEKKARKAMSKLGLR-QIQGVTRI 1435
A + + PQT CP + S + +++ +KA A S G + G T+
Sbjct: 629 AAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQR 688
Query: 1436 TIQKSKNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAAAEKFK---------- 1485
+ S + ++ + + V G+AK QV KAA+ K
Sbjct: 689 PAEDSSS-----SEESDSEEEKTGLAVTVGQAKSVGKGLQV-KAASVPVKGSLGQGTAPV 742
Query: 1486 VPSEPSALVPESAPRPRVRLECKEEEEEEEEEVDEAGLELRDIELVMAQANVSRAKAVRA 1545
+P + V + + E EEE + EE ++ A+AN + A+A A
Sbjct: 743 LPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSA 802
>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
Length = 1427
Score = 84.7 bits (208), Expect = 6e-16
Identities = 142/568 (25%), Positives = 201/568 (35%), Gaps = 53/568 (9%)
Query: 738 KPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSA-PKPVAAATIVSQQAEEGLTL 796
K V A EE + + Q + T +P L +A P P +I + A EG +
Sbjct: 812 KQVTKAGNTEPVLEEWIPVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAV 871
Query: 797 PQDSAMTPPLPLQDTDLSSA----PKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTD 852
A P P +D ++S + V AA + A E T+P + P
Sbjct: 872 V---AALVPFPHEDILVASIVSLEEEDVTAAAV---SAPERATVPAVTVSVPEGTAAVAA 925
Query: 853 LSS----APKPVAAATPVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQ 908
+SS AP AA T A G + P+ +A+ +P+ + D + PV AT V
Sbjct: 926 VSSPEETAPAVAAAITQEGMSAVAGFS-PEWAALAITVPITEED-GTPEGPVTPATTVHA 983
Query: 909 QAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPVATMAQQE 968
E P +A+ P + P + AV TP+ + A P E + A
Sbjct: 984 PEE-----PDTAAVRVSTPEEPASPAA-----AVPTPEEPTSPAAAVPTPEEPTSPAA-- 1031
Query: 969 VGEALGPRPAPEEKNAALPTVPEP---AALDQVQQDDPQPAAEAGTPWAAQEDADSTLGM 1025
A+ P P AA+PT EP AA ++ PAA TP A +
Sbjct: 1032 ---AVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTP 1088
Query: 1026 EALSLPEPASGAGEEI---AEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEG 1082
E + P A EE A A+ P A A T P+ P V +E
Sbjct: 1089 EEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPT-----PEEPASPAAAVPTPEEP 1143
Query: 1083 GLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKST-PEPTLPS 1141
P P + A VP +A P A + +PA + +T EPT P+
Sbjct: 1144 AF-PAPAVPTPEESASAAVAVPTPEESASPA---AAVPTPAESASFAAVVATLEEPTSPA 1199
Query: 1142 A-VATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSV 1200
A V T A++ + E +S+ + PA +A S EP +V E S
Sbjct: 1200 ASVPTPAAMVATLEEFTSPAASVPTS--EEPASLAAAVSNPEEPTSPAAAVPTLEEPTSS 1257
Query: 1201 LGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVE 1260
L PE L+ S P +A L A P P P + P
Sbjct: 1258 AAAVLT--PEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPT 1315
Query: 1261 DEEPPGSLGLPPPQAGVQPAAAAVSGTT 1288
E P PP V P G +
Sbjct: 1316 PEVPAIPAAAVPPMEEVSPIGVPFLGVS 1343
Score = 84.0 bits (206), Expect = 1e-15
Identities = 142/590 (24%), Positives = 211/590 (35%), Gaps = 106/590 (17%)
Query: 698 KPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSA-PKPVAAATLVSQQAEEGLTL 756
K V A EE + + Q + T +P L +A P P ++ + A EG +
Sbjct: 812 KQVTKAGNTEPVLEEWIPVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAV 871
Query: 757 PQDSAMTPPLPLQDTDLSSA----PKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTD 812
A P P +D ++S + V AA + A E T+P + P
Sbjct: 872 V---AALVPFPHEDILVASIVSLEEEDVTAAAV---SAPERATVPAVTVSVPEGTAAVAA 925
Query: 813 LSS----APKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQ 868
+SS AP AA T A G + P+ +A+ +P+ + D + PV AT V
Sbjct: 926 VSSPEETAPAVAAAITQEGMSAVAGFS-PEWAALAITVPITEED-GTPEGPVTPATTVHA 983
Query: 869 QAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPL 928
E P +A+ P + P AAA P ++ P A P P
Sbjct: 984 PEE-----PDTAAVRVSTPEE-------PASPAAAVPTPEE-------PTSPAAAVPTPE 1024
Query: 929 QDTGPTSGPEP--------LAVATPQTLQAEAGCAP----GTEPVATM-AQQEVGEALGP 975
+ T P + P AV TP+ + A P T P A + +E
Sbjct: 1025 EPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAA 1084
Query: 976 RPAPEEKN---AALPTVPE---PAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALS 1029
P PEE AA+PT E PAA ++ PAA TP A + E +
Sbjct: 1085 VPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPA 1144
Query: 1030 LPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQ 1089
P PA EE A A +P+ E+ P
Sbjct: 1145 FPAPAVPTPEESASA------------------AVAVPTPE------ESASPAAAVPTPA 1180
Query: 1090 EHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVATEASL 1149
E +A+ E P +P A+ P + + EE S P P+++A S
Sbjct: 1181 ESASFAAVVATLEEPTSPAASVPTPA---AMVATLEEFTSPAASVPTSEEPASLAAAVSN 1237
Query: 1150 DSCPESSVGAVSSLDRGCPDAPA----------PTSAPTSQQP-EPVLGLGSVEQPHEVP 1198
P S AV +L+ A A S PT ++P P + ++E+P
Sbjct: 1238 PEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPA 1297
Query: 1199 SVLGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAP 1248
+ + TP + P+ V P P P + AA+PP+E +P
Sbjct: 1298 AAVPTPEV-------AAIPAASV-----PTPEVP-AIPAAAVPPMEEVSP 1334
Score = 58.2 bits (139), Expect = 6e-08
Identities = 109/496 (21%), Positives = 177/496 (35%), Gaps = 84/496 (16%)
Query: 962 ATMAQQEVGEALGPRPAPEEKNAALPTVPEP------AALDQVQQDDPQPAA-----EAG 1010
A + E G ++ PAPE VP P A++ ++++D AA A
Sbjct: 849 AALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERAT 908
Query: 1011 TPWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPD--- 1067
P + T + A+S PE + A +A A+++ G A G P+
Sbjct: 909 VPAVTVSVPEGTAAVAAVSSPEETAPA---VAAAITQEGMSAVA--------GFSPEWAA 957
Query: 1068 -SPQKETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREE 1126
+ E + EG + P H P P+ + R+ +P EE
Sbjct: 958 LAITVPITEEDGTPEGPVTPATTVHAPEE----------------PDTAAVRVSTP--EE 999
Query: 1127 RGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQP-EPV 1185
+ P P P++ A P S AV + P +PA + PT ++P P
Sbjct: 1000 PASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEE--PTSPA-AAVPTPEEPTSPA 1056
Query: 1186 LGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALP-PLE 1244
+ + E+P + + TP +P++P P P P T AA+P P E
Sbjct: 1057 AAVPTPEEPTSPAAAVPTP----------EEPTSPAAAV--PTPEEP-TSPAAAVPTPEE 1103
Query: 1245 PPAPCLCQDPQED------SVEDEEPPGS--LGLPPPQAGVQPAAAA----VSGTTQPLG 1292
P +P E+ +V E P S +P P+ PA A S +
Sbjct: 1104 PTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAV 1163
Query: 1293 TGPRVSLSPHSPLLSPKVASMDAKDLAL---QILPPCQVPPPSGPQSPAGPQGLSAPEQQ 1349
P S SP + + +P ++ A +A P VP P+ A + ++P
Sbjct: 1164 PTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAA--MVATLEEFTSPAAS 1221
Query: 1350 EDEDSLEEDSPRALGSGQHSDSHGESSAELDEQD-----ILAPQTVQCPAQAPAGGSEET 1404
A+ + + S + L+E +L P+ + PA + E
Sbjct: 1222 VPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPA 1281
Query: 1405 IAKAKQSRSEKKARKA 1420
A S E+ A A
Sbjct: 1282 SPAAAVSNLEEPASPA 1297
>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
Length = 2217
Score = 82.0 bits (201), Expect = 4e-15
Identities = 183/763 (23%), Positives = 262/763 (34%), Gaps = 157/763 (20%)
Query: 687 PLQDTDLSSAPK----PVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAA 742
P + D+ S K PV V+ A+ G P + P P D L P +A
Sbjct: 552 PKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPE----PEEPEADQHLLPPTLPTSA 607
Query: 743 ATLVSQQ---AEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQD 799
+L S + +G T+ DS + + + +AP P A + S EG LPQ
Sbjct: 608 TSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSP--AQCVCSPPVSEGPVLPQS 665
Query: 800 ----SAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLT----LPQDSAMTPPLPLQDT 851
A P + S P P ++ + ++ LP S P P Q
Sbjct: 666 LPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTGPGQPA 725
Query: 852 DLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAE 911
P P+A TP LPQ A P +PLQ P +A A+ V A+
Sbjct: 726 PPGQQPPPLAQPTP----------LPQVLAPQPVVPLQPVP-PHLPPYLAPASQVGAPAQ 774
Query: 912 -EGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPVATMAQQEVG 970
+ L +PQ APL +PLA PQ P P+ +A G
Sbjct: 775 LKPLQMPQ-----APL-----------QPLAQVPPQMPP-----IPVVPPITPLA----G 809
Query: 971 EALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSL 1030
P P+ A +P VP P PA + A A L ++A+ L
Sbjct: 810 IDGLPPALPDLPTATVPPVPPPQYF--------SPAVILPSLAAPLPPASPALPLQAVKL 861
Query: 1031 PEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQE 1090
P P PG + R P++P T+ + G+ L
Sbjct: 862 PHP--------------PGAPLAMPCRT-----IVPNAP--ATIPLLAVAPPGVAAL--- 897
Query: 1091 HGPRSALGGAREVPDAP--PAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVATEAS 1148
S ++P P PAA P+++ + + P+P LP
Sbjct: 898 ----SIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALP-------- 945
Query: 1149 LDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPS-VLGTPLLQ 1207
P+ ++ P P PT P+PVL QP P VL +
Sbjct: 946 ----PQPTL----------PPQPVLPPQPT-LPPQPVL----PPQPTRPPQPVLPPQPML 986
Query: 1208 PPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALPP----LEPPAPCLCQDPQEDSVEDEE 1263
PP+ + QP+ PV RP P P A AA P L PAP D
Sbjct: 987 PPQPVLPPQPALPV-RPEPLQPHLPEQAAPAATPGSQILLGHPAP-YAVDVAAQVPTVPV 1044
Query: 1264 PPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLALQIL 1323
PP ++ PP + PAA P + S L + + +L
Sbjct: 1045 PPAAVLSPPLPEVLLPAA-------------PELLPQFPSSLATVSASVQSVPTQTATLL 1091
Query: 1324 PPCQVPPPSGP--QSPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELDE 1381
PP P P GP SP L+ QE++ S +D P G Q +S+G S
Sbjct: 1092 PPANPPLPGGPGIASPCPTVQLTVEPVQEEQAS--QDKPP--GLPQSCESYGGS------ 1141
Query: 1382 QDILAPQTVQCPAQAPAGGSE-ETIAKAKQSRSEKKARKAMSK 1423
D+ + + + + GG E A K R +AR +
Sbjct: 1142 -DVTSGKELSDSCEGAFGGGRLEGRAARKHHRRSTRARSRQER 1183
Score = 74.7 bits (182), Expect = 6e-13
Identities = 217/950 (22%), Positives = 324/950 (34%), Gaps = 148/950 (15%)
Query: 478 ESTATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAM-----AMPQPSQEGI 532
E+ + P TL + +T + Q +DS + Q+S + A P P+Q
Sbjct: 593 EADQHLLPPTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVC 652
Query: 533 SEILGQESVTAEKLPT-------------PQEETSLTLCPDSPQNLKEEGGLD------- 572
S + + V + LP+ P CP S Q + +
Sbjct: 653 SPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPP 712
Query: 573 ----LPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQ 628
+P+G A P + LPQ A P +PLQ P A+ + +
Sbjct: 713 PSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAP 772
Query: 629 QAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGL--TLPQ-DSAMTPP 685
+ L +PQ P PL P PV + +GL LP +A PP
Sbjct: 773 AQLKPLQMPQ----APLQPLAQVPPQMPPIPV-VPPITPLAGIDGLPPALPDLPTATVPP 827
Query: 686 LPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATL 745
+P P+ + A ++ A LP S P LPLQ L P P A
Sbjct: 828 VP--------PPQYFSPAVILPSLA---APLPPAS---PALPLQAVKL---PHPPGAPLA 870
Query: 746 VSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPP 805
+ + T+ ++ T PL L+ AP VAA +I S A+ LP
Sbjct: 871 MPCR-----TIVPNAPATIPL------LAVAPPGVAALSIHSAVAQ----LPGQPVYPAA 915
Query: 806 LP-LQDTDLSSAPKPVA---AATIVSQQAEEGLTLPQDSAM-----TPPLPLQDTDLSSA 856
P + TD+ +P AT TLP + PP P+ +
Sbjct: 916 FPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRP 975
Query: 857 PKPVAAATPVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTL 916
P+PV P+ + + PQ + P PLQ P+ A A Q G
Sbjct: 976 PQPVLPPQPM--LPPQPVLPPQPALPVRPEPLQ----PHLPEQAAPAATPGSQILLGHPA 1029
Query: 917 PQDSAMTAPLPLQDTGPTSG-----PEPLAVATPQTL----QAEAGCAPGTEPVATMAQQ 967
P + A +P P + PE L A P+ L + A + + V T
Sbjct: 1030 PYAVDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTAT 1089
Query: 968 EVGEALGPRPAPEEKNAALPTVP---EPAALDQVQQDDPQPAAEAGTPWAAQE--DADST 1022
+ A P P + PTV EP +Q QD P G P + + +D T
Sbjct: 1090 LLPPANPPLPGGPGIASPCPTVQLTVEPVQEEQASQDKP-----PGLPQSCESYGGSDVT 1144
Query: 1023 LGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEG 1082
G E E A G G A + R + AR+ + P+ L V N +
Sbjct: 1145 SGKELSDSCEGAFGGGRLEGRAARKHHRRS-TRARSRQ---ERASRPRLTILNVCNTGDK 1200
Query: 1083 GLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSA 1142
++ + H + DAP + + + A E +
Sbjct: 1201 MVECQLETHNHKMVTFKFDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDVMDKAEDM 1260
Query: 1143 VA--TEASLDSCPESSVGAVSS--LDRGCPDAPAPTSAPTSQQPE-----------PVLG 1187
++ T+A S P +S +S+ L G + +AP QQ PV
Sbjct: 1261 LSEDTDADRGSDPGTSPPHLSTCGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAE 1320
Query: 1188 LGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTL--------AGAA 1239
+ E P P + + L PPE Q S P L P L AG +
Sbjct: 1321 HPAPEAPESSPPLPLSSL--PPE---ASQDSAPYKDQLS-SKEQPSFLASQQLLSQAGPS 1374
Query: 1240 LPPLEPPAPCLCQDPQEDSV-EDEEPPGSLGLPPPQAGVQPAA---AAVSGTTQPLGTGP 1295
PP PPAP P ++ +D P + +P P +G A G T L T
Sbjct: 1375 NPPGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQ 1434
Query: 1296 RVSLSPHSPL--------LSPKVASMDAKDLALQILPPCQVPPPSGPQSP 1337
++ + +PL L+P + +A P +PPP+ SP
Sbjct: 1435 PLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSP 1484
Score = 54.3 bits (129), Expect = 9e-07
Identities = 157/684 (22%), Positives = 236/684 (34%), Gaps = 117/684 (17%)
Query: 563 QNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAA 622
Q L + G P G P A P LPQD A + + +A +
Sbjct: 1365 QQLLSQAGPSNPPGAPPAPLAPSSPPVT----ALPQDGAAPATSTMPEPASGTASQAGGP 1420
Query: 623 ATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAP---KPVAAATLVSQQAEEGLTLPQD 679
T +E + P PL +Q + AP P AA+T + E L P
Sbjct: 1421 GTPQGLTSELETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAP 1480
Query: 680 SAMT---PPLPLQDTDLSSAPKPVAAATLVSQQAEE---GLTLPQDSAMTPPLPLQDTDL 733
P P P V A +L + Q G T+P PP L+
Sbjct: 1481 EPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQ----PPSALESDGE 1536
Query: 734 SSAPKPVAAATLVSQQAEEGLTL------PQDSAMT-PPLPLQDTDLSSAPK-------- 778
P+ + + E+ TL P SA P+ + D D + P
Sbjct: 1537 GPPPRVGFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQPRSE 1596
Query: 779 --------PVAAATIVSQQAEEGLTLPQDSAMTPPL-PLQDTDLSSAPKPVAAATIVSQQ 829
P VS + + L + S + P + + SS+ ++ +
Sbjct: 1597 VCGGDLALPPVPKEAVSGRVQLPQPLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGY 1656
Query: 830 AEEGLTLPQDSAMTPPLP-----------LQDTDL-------SSAPKPVAAATPVSQQAE 871
+G + DS + P +P ++ TD SSA P + V QA
Sbjct: 1657 DRDGRQVASDSHVVPSVPQDVPAFVRPARVEPTDRDGGEAGESSAEPPPSDMGTVGGQAS 1716
Query: 872 EGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQ-D 930
TL + +P + D+SS K V + VS Q E L P +AP + D
Sbjct: 1717 HPQTLGARALGSPRKRPEQQDVSSPAKTVGRFSVVSTQDEWTLASPHSLRYSAPPDVYLD 1776
Query: 931 TGPTSGPEPLAVATPQTLQA-EAGCAPGTEPVATMAQQEVGEALGPRPAPE-EKNAALPT 988
P+S LAV QT + E G EPV++ + E GPR P +K A+LP
Sbjct: 1777 EAPSSPDVKLAVRRAQTASSIEVGVG---EPVSSDSGDE-----GPRARPPVQKQASLP- 1827
Query: 989 VPEPAALDQVQQ-----DDPQPAAEAG----------------TPWAAQ----------- 1016
V A D V++ P A G T + +Q
Sbjct: 1828 VSGSVAGDFVKKATAFLQRPSRAGSLGPETPSRVGMKVPTISVTSFHSQSSYISSDNDSE 1887
Query: 1017 -EDADSTLGMEAL------SLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSP 1069
EDAD +++L + E S +EI R G+ L A P
Sbjct: 1888 LEDADIKKELQSLREKHLKEISELQSQQKQEIEALYRRLGKP--LPPNVGFFHTAPPTGR 1945
Query: 1070 QKETLEVENQQEGGLKPLAQE-HGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERG 1128
+++T + + + L PL ++ S+ G + PPA P + L + + G
Sbjct: 1946 RRKTSKSKLKAGKLLNPLVRQLKVVASSTGHLADSSRGPPAKDPAQASVGLTA---DSTG 2002
Query: 1129 LSGKSTPEPTLPSAVATEASLDSC 1152
LSGK+ + P +V S D C
Sbjct: 2003 LSGKAV-QTQQPCSVRASLSSDIC 2025
Score = 46.6 bits (109), Expect = 2e-04
Identities = 92/401 (22%), Positives = 134/401 (33%), Gaps = 86/401 (21%)
Query: 1062 DGAKPDSPQKETLEVENQQEG-GLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLL 1120
+ ++ +P K+ L + Q + L + GP + P APPA S
Sbjct: 1341 EASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNP-------PGAPPAPLAPSSPPVTA 1393
Query: 1121 SPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQ 1180
P G + T+P + AS P + G S L+ TS P ++
Sbjct: 1394 LPQ------DGAAPATSTMPEPASGTASQAGGPGTPQGLTSELE---------TSQPLAE 1438
Query: 1181 QPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAAL 1240
E L + P V+G P A + ++ PL P P +G
Sbjct: 1439 THEAPLAVQ--------PLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQ 1490
Query: 1241 PPLEPPAPCL-------------CQDPQEDSVEDEEPPGSLGL----PPPQAGV------ 1277
P L PAP L P +PP +L PPP+ G
Sbjct: 1491 PALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPPPRVGFVDSTIK 1550
Query: 1278 --------------QPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVAS-MDAKDLALQI 1322
P ++A +GT P+ G R PL + S + DLAL
Sbjct: 1551 SLDEKLRTLLYQEHVPTSSASAGT--PVEVGDRDFTL--EPLRGDQPRSEVCGGDLALPP 1606
Query: 1323 LPP------CQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSPRAL------GSGQHSD 1370
+P Q+P P +S P + EQ E SPR++ G SD
Sbjct: 1607 VPKEAVSGRVQLPQPLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVASD 1666
Query: 1371 SHGESSAELDEQDILAPQTVQCPAQAPAGGSEETIAKAKQS 1411
SH S D + P V+ P G + E+ A+ S
Sbjct: 1667 SHVVPSVPQDVPAFVRPARVE-PTDRDGGEAGESSAEPPPS 1706
Score = 45.8 bits (107), Expect = 3e-04
Identities = 57/209 (27%), Positives = 77/209 (36%), Gaps = 17/209 (8%)
Query: 13 PEADRPGPRTDLSCDAAAATTILGGDRREPCALTPGPSHLALTFLPSKPGARPQPEGASW 72
PE+ P P + L +A+ + ++ + PS LA L S+ G P
Sbjct: 1327 PESSPPLPLSSLPPEASQDSA----PYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPPA 1382
Query: 73 DAGPGGAPSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIVMGE-ETCQALLS 131
P P P+ +PE S A ++A P T P+ + E ET Q L
Sbjct: 1383 PLAPSSPPVTALPQDGAAPATSTMPEPASGTA--SQAGGPGT--PQGLTSELETSQPLAE 1438
Query: 132 PRAARTALRDQEGGHASPDPPPELCSQGDLSVPS---PPPDPDSFFTPPSTPTKTTYALL 188
A A++ G A P PE S D S P PPP P+ PS + T L
Sbjct: 1439 THEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPE-----PSPHSGTPQPAL 1493
Query: 189 PACGPHGDARDSEAELRDELLDSPPASPS 217
P A L L SPP P+
Sbjct: 1494 GQPAPLLPAAVGAVSLATSQLPSPPLGPT 1522
Score = 45.4 bits (106), Expect = 4e-04
Identities = 97/407 (23%), Positives = 151/407 (37%), Gaps = 49/407 (12%)
Query: 437 QDGTV---SWAVEAAPQTSDRGAYLSQRQELISEV-TEEGLALGQESTATVTPHTLQVAP 492
QDG S E A T+ + Q L SE+ T + LA E+ V P + +AP
Sbjct: 1396 QDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETHEAPLAVQPLVVGLAP 1455
Query: 493 GLQV-EVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEIL----GQESVTAEKLP 547
E A+ A E A + S PQP+ + +L G S+ +LP
Sbjct: 1456 CTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLP 1515
Query: 548 TPQEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQD----SAMT 603
+P T+ P P L+ +G + P R +TI K L Q+ S+ +
Sbjct: 1516 SPP--LGPTVPPQPPSALESDG--EGPPPRVGFVDSTIKSLDEKLRTLLYQEHVPTSSAS 1571
Query: 604 PPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTE-LSSAPKPVAA 662
P++ D +P+ S+ L LP P+P + P+P+
Sbjct: 1572 AGTPVEVGDRDFTLEPLRGDQPRSEVCGGDLALP-------PVPKEAVSGRVQLPQPLVE 1624
Query: 663 ATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAA----ATLVSQQAEEGLTLPQ 718
+ ++ + S+MT S+P+ + V+ + ++PQ
Sbjct: 1625 KSELAPTRGAVMEQGTSSSMTA---------ESSPRSMLGYDRDGRQVASDSHVVPSVPQ 1675
Query: 719 D-SAMTPPLPLQDTDL-------SSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQD 770
D A P ++ TD SSA P + V QA TL + +P +
Sbjct: 1676 DVPAFVRPARVEPTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTLGARALGSPRKRPEQ 1735
Query: 771 TDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAP 817
D+SS K V ++VS Q E L P + P D L AP
Sbjct: 1736 QDVSSPAKTVGRFSVVSTQDEWTLASPHSLRYSAP---PDVYLDEAP 1779
Score = 39.3 bits (90), Expect = 0.030
Identities = 42/139 (30%), Positives = 55/139 (39%), Gaps = 10/139 (7%)
Query: 951 EAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAG 1010
EA APG +P + Q+ V R E+ P P PAAL Q P A+AG
Sbjct: 58 EAAEAPGPQPPQPL-QRRVLLLCKTRRLIAERARGRPAAPAPAAL-VAQPGAPGAPADAG 115
Query: 1011 -TPWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSP 1069
P QE + + P P G EE A A R E EA+ +P
Sbjct: 116 PEPVGTQEPGPDPIAAAVETAPAPDGGPREE-AAATVRKEDEGAAEAK------PEPGRT 168
Query: 1070 QKETLEVENQQEGGLKPLA 1088
+++ E E E LK +A
Sbjct: 169 RRDEPEEEEDDEDDLKAVA 187
Score = 34.3 bits (77), Expect = 0.97
Identities = 44/174 (25%), Positives = 63/174 (36%), Gaps = 18/174 (10%)
Query: 53 ALTFLPS-KPGARPQPEGASWDAGPGGAPSAWADPGEGGPSPMLLPEGLSSQALSTEAPL 111
A++F P P + P P G A PG P A P LP+ L+ Q + P+
Sbjct: 703 AMSFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTP-------LPQVLAPQPVVPLQPV 755
Query: 112 PATLEPRIVMGEET-----CQALLSPRAARTALRDQEGGHASPDP--PPELCSQGDLSVP 164
P L P + + + L P+A L Q P P PP G +P
Sbjct: 756 PPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLA-QVPPQMPPIPVVPPITPLAGIDGLP 814
Query: 165 SPPPDPDSFFTPPSTPTK--TTYALLPACGPHGDARDSEAELRDELLDSPPASP 216
PD + PP P + + +LP+ L+ L PP +P
Sbjct: 815 PALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVKLPHPPGAP 868
Score = 31.6 bits (70), Expect = 6.3
Identities = 37/133 (27%), Positives = 47/133 (35%), Gaps = 34/133 (25%)
Query: 1173 PTSAPTSQQPEPVLGLGSVEQPHEVPSVLGT---PLLQPPENL----------------- 1212
P + P+ L VE E P L P QPP+ L
Sbjct: 29 PRAKAARPGPQRFLRRSVVESDQEEPPGLEAAEAPGPQPPQPLQRRVLLLCKTRRLIAER 88
Query: 1213 AKGQPSTPVDRPLGPDPSAPGTLAGAALPPL--EPPAPCLCQDPQEDSVEDEEPPGSLGL 1270
A+G+P+ P L P APG A A P+ + P P DP +VE
Sbjct: 89 ARGRPAAPAPAALVAQPGAPGAPADAGPEPVGTQEPGP----DPIAAAVET--------A 136
Query: 1271 PPPQAGVQPAAAA 1283
P P G + AAA
Sbjct: 137 PAPDGGPREEAAA 149
>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
[Homo sapiens]
Length = 1412
Score = 79.0 bits (193), Expect = 3e-14
Identities = 197/952 (20%), Positives = 337/952 (35%), Gaps = 141/952 (14%)
Query: 510 ETDSTAGQESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLTLCPDSPQNLKEEG 569
E D+ + ++ P + E E E+ TA+ P S L D P ++KE+
Sbjct: 66 EEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKA 125
Query: 570 GLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQ 629
+ K +P A S +P + +P A T+VS+
Sbjct: 126 KAETEKAGK---TGNSMPHPATGKTVANLLSGKSP---------RKSAEPSANTTLVSET 173
Query: 630 AEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAAT----LVSQQAEEGLTLPQDSAMTPP 685
EEG ++P P + + S+ + ++++ + + +E+ L + SA
Sbjct: 174 EEEG-SVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKG 232
Query: 686 LPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATL 745
P + P P A V+ Q + G P++ + + + S + + AA
Sbjct: 233 TP----GKGATPAPPGKAGAVASQTKAG--KPEEDSES-----SSEESSDSEEETPAAKA 281
Query: 746 VSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPK----PVAAATIVSQQAEEGLTLPQDSA 801
+ Q G T +A P + AP P A ++ E+ + ++S
Sbjct: 282 LLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESD 341
Query: 802 MTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVA 861
P Q AP+ AA+ + +G P P + T P A
Sbjct: 342 SEEEAPAQAKPSGKAPQVRAASAPAKESPRKG---------AAPAPPRKTG------PAA 386
Query: 862 AATPVSQQAEEGLTLPQDSAMTPPLPLQDTDLSS-APKPVAAATPVSQQAEEGLTLPQDS 920
A V +Q E+ + ++S D+D + A A P+ + + P +
Sbjct: 387 AQVQVGKQEEDSRSSSEES---------DSDREALAAMNAAQVKPLGKSPQ---VKPAST 434
Query: 921 AMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAG---------------CAPGTEPVATMA 965
PL G +GP P P T A+ G + G P A
Sbjct: 435 MGMGPL-----GKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAP 489
Query: 966 QQE--VGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTL 1023
QE +G L +P P P A+ QV+ + P +E +++E +DS
Sbjct: 490 AQEKSLGNILQAKPTSSPAKGP-PQKAGPVAV-QVKAEKPMDNSE-----SSEESSDSAD 542
Query: 1024 GMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGG 1083
EA PA+ + AL P +AC + +T AK +P + + +
Sbjct: 543 SEEA-----PAAMTAAQAKPALKIPQTKAC-PKKTNTTASAKV-APVRVGTQAPRKAGTA 595
Query: 1084 LKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAV 1143
P G A+ G + P A ++ E S + E+ GL+ ++ +
Sbjct: 596 TSPA----GSSPAVAGGTQRP-AEDSSSSEESDSE-----EEKTGLAVTVGQAKSVGKGL 645
Query: 1144 ATEASLDSCPESSVGAVSSLDRG-CPDAPAPTSAPTSQ-QPEPVLGLGSVEQPHEVPSVL 1201
+A +SV SL +G P P T +Q + E S E+ +
Sbjct: 646 QVKA-------ASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAA 698
Query: 1202 GTPL---LQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAAL-------PPLEPPAPCLC 1251
+P + AK P+ SAPG + AA ++PP
Sbjct: 699 ASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPV---- 754
Query: 1252 QDPQEDSVEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLS-PHSPLLSPKV 1310
++PQ +V G +P V AA A +G + G+ S S + L+
Sbjct: 755 RNPQNSTVLAR---GPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVK 811
Query: 1311 ASMDAKDLALQILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSD 1370
S + + P + P +P G G SA + + +DS S + SD
Sbjct: 812 PSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDS--------GSSSEESD 863
Query: 1371 SHGESSAELDEQDILAPQTVQCPAQAPAGGSEETIAKAKQSRSEKKARKAMS 1422
S GE+ A + ++ P + G T A+A+ + + +KAR + S
Sbjct: 864 SDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASES 915
Score = 65.1 bits (157), Expect = 5e-10
Identities = 226/1050 (21%), Positives = 365/1050 (34%), Gaps = 210/1050 (20%)
Query: 406 SGEPHAQATLLQDSVQKTEEESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLSQRQELI 465
S EP A TL V +TEEE A G A+ G VS A +S+ + S ++
Sbjct: 160 SAEPSANTTL----VSETEEEGSVPAFGAAAKPGMVS--AGQADSSSEDTSSSSDETDVE 213
Query: 466 SEVTEEGLALGQEST-ATVTPH--TLQVAPGLQVEVATRVTPQAGEEETDSTAGQES--- 519
+ +E+ L + S A TP PG VA++ EE+++S++ + S
Sbjct: 214 VKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSE 273
Query: 520 ----AAMAMPQPSQEGISEILGQESVTAEK------LPTPQEETSLTLCPDSPQNLKEEG 569
AA A+ Q G + +G S A++ P P +T + +E
Sbjct: 274 EETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREE-- 331
Query: 570 GLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKP------VAAA 623
D S + + P QAK PQ A + P + +AP P AA
Sbjct: 332 --DSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAK-ESPRKGAAPAPPRKTGPAAAQ 388
Query: 624 TIVSQQAEEGLTLPQDS-----VMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQ 678
V +Q E+ + ++S + Q L +P+ A+T+ +G
Sbjct: 389 VQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVP 448
Query: 679 DSAMTPPLPL---------------QDTDLSSAPKPVAAATLVSQQAEEGLTLPQDS--A 721
+ P P + +D S P A A + L S A
Sbjct: 449 PGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPA 508
Query: 722 MTPPL-------------PLQDTDLS-----SAPKPVAAATLVSQQAEEGLTLPQDSAMT 763
PP P+ +++ S SA A A + + QA+ L +PQ A
Sbjct: 509 KGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACP 568
Query: 764 PPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPL------PLQDTDLS--- 814
+ T+ +++ K VA + +Q + T + +P + P +D+ S
Sbjct: 569 -----KKTNTTASAK-VAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEES 622
Query: 815 -SAPKPVAAATIVSQQAEEGLTLPQDSAMTPP-----------LP--------------L 848
S + A V Q G L +A P LP
Sbjct: 623 DSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQ 682
Query: 849 QDTDLSS--APKPVAAATPVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPV 906
+D++ S + AAA+P + T + + P +S+ K V AA
Sbjct: 683 EDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQA 742
Query: 907 SQQA----EEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGC-------- 954
Q++ + + PQ+S + A GP S P + A QA+ G
Sbjct: 743 KQRSPSKVKPPVRNPQNSTVLA------RGPASVPS-VGKAVATAAQAQTGPEEDSGSSE 795
Query: 955 --APGTEPVATMAQ-------QEVGEALGPRPAPEEKNAALPTVPE---PAALDQVQQDD 1002
+ E T+AQ ++ AL P K AA PT P P+A +QDD
Sbjct: 796 EESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAA-PTPPGKTGPSAAQAGKQDD 854
Query: 1003 PQPAAEAGTPWAAQEDADSTLGMEALSLPEPA--------SGAGEEI----AEALSRPGR 1050
++E + D ++ + + + +P S AG A+A S P +
Sbjct: 855 SGSSSEE-----SDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRK 909
Query: 1051 EACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAA 1110
E+ A + +S ++ + G++ +P A P
Sbjct: 910 ARASESTARSSSS---ESEDEDVIPATQCLTPGIRT------------NVVTMPTAHPRI 954
Query: 1111 CPEVSQARLLSPAREERGLSGKSTPEP----------TLP------SAVATEASLDSCPE 1154
P+ S A S R GK P +LP +A +AS P
Sbjct: 955 APKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPV 1014
Query: 1155 SSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLAK 1214
+ S +D PA + TS Q + G + +P ++P V + PE+
Sbjct: 1015 ARTQPSSGVDSAVGTLPATSPQSTSVQAK---GTNKLRKP-KLPEV--QQATKAPESSDD 1068
Query: 1215 GQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAP----CLCQDPQEDSVEDE--EPPGSL 1268
+ S+ D G + G + L P P L ++ +S ED+ P SL
Sbjct: 1069 SEDSS--DSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSL 1126
Query: 1269 GLPPPQAGVQPAAAAVSGTTQPLGTGPRVS 1298
G+ PA + S T L + P VS
Sbjct: 1127 LSGYMTPGLTPANSQASKATPKLDSSPSVS 1156
Score = 59.7 bits (143), Expect = 2e-08
Identities = 165/765 (21%), Positives = 271/765 (35%), Gaps = 134/765 (17%)
Query: 809 QDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAM-TPPLPLQDTDLSSAPKPVAAATPVS 867
+D L + V+ S+ +EE ++A TP L ++ + A P +
Sbjct: 67 EDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAK 126
Query: 868 QQAEE----GLTLPQDSA-MTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAM 922
+ E+ G ++P + T L + +P A T VS+ EEG ++P A
Sbjct: 127 AETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEG-SVPAFGAA 185
Query: 923 TAPLPL---------QDTGPTSGPEPLAV-ATPQTLQAEAGCAPGTEPVATMAQQEVGEA 972
P + +DT +S + V A+ + LQ A AP A+ G+
Sbjct: 186 AKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAP--------AKGTPGK- 236
Query: 973 LGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLPE 1032
G PAP K A+ + Q + P+ +E+ + ++ + + T +AL L
Sbjct: 237 -GATPAPPGKAGAVAS--------QTKAGKPEEDSESSSEESSDSE-EETPAAKAL-LQA 285
Query: 1033 PASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHG 1092
ASG ++ A S P +E+ + GA P P K V Q G + +Q
Sbjct: 286 KASGKTSQVGAA-SAPAKESPRK-------GAAPAPPGKTGPAVAKAQAGKREEDSQSSS 337
Query: 1093 PRSALGGAREVPDAPPAACPEVSQARLLSPAREE-RGLSGKSTPEPTLPSAVATEASLDS 1151
S P P+V A +PA+E R + + P T P+A +
Sbjct: 338 EESDSEEEAPAQAKPSGKAPQVRAAS--APAKESPRKGAAPAPPRKTGPAAAQVQVGKQE 395
Query: 1152 CPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPEN 1211
S S DR +A + Q +P LG +P ++P
Sbjct: 396 EDSRSSSEESDSDREA------LAAMNAAQVKP---LGK------------SPQVKPAST 434
Query: 1212 LAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGLP 1271
+ G P+ + GP P PG + P P A + +S +E S G
Sbjct: 435 MGMG----PLGKGAGPVP--PGKVG-----PATPSAQVGKWEEDSESSSEESSDSSDGEV 483
Query: 1272 PPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLALQILPPCQVPPP 1331
P V PA G +L K S AK
Sbjct: 484 P--TAVAPAQEKSLGN-----------------ILQAKPTSSPAK--------------- 509
Query: 1332 SGPQSPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELDEQDILAPQTVQ 1391
GP AGP + ++ ++S E S + S ++ +A + + PQT
Sbjct: 510 -GPPQKAGPVAVQVKAEKPMDNS--ESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKA 566
Query: 1392 CPAQAPAGGSEETIAKAKQSRSEKKARKAMSKLGLR-QIQGVTRITIQKSKNILFVIAKP 1450
CP + S + +++ +KA A S G + G T+ + S + ++
Sbjct: 567 CPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSS-----SEE 621
Query: 1451 DVFKSPASDTYVVFGEAKIEDLSQQVHKAAAEKFK----------VPSEPSALVPESAPR 1500
+ + V G+AK QV KAA+ K +P + V +
Sbjct: 622 SDSEEEKTGLAVTVGQAKSVGKGLQV-KAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAE 680
Query: 1501 PRVRLECKEEEEEEEEEVDEAGLELRDIELVMAQANVSRAKAVRA 1545
+ E EEE + EE ++ A+AN + A+A A
Sbjct: 681 KQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSA 725
Score = 56.2 bits (134), Expect = 2e-07
Identities = 167/805 (20%), Positives = 269/805 (33%), Gaps = 110/805 (13%)
Query: 328 PLSPEEEEEEAVADPDPGGDLAGEGEEDSTSASFLQSLSDL----SITEGMDEAFAFRDD 383
P EE+ ++ + G G+ S + + S+ +G +
Sbjct: 612 PAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTG 671
Query: 384 TSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSVQKTEEESGGGAKGLQAQDGTVS- 442
+ ++ +E+ +E S E A ++ SV+KT+ ++ A + GT+S
Sbjct: 672 PTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISA 731
Query: 443 --WAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQESTATVTPHTLQVAPGLQVEVAT 500
V AA Q R + + + LA G S +V VA Q +
Sbjct: 732 PGKVVTAAAQAKQRSP-SKVKPPVRNPQNSTVLARGPASVPSVGK---AVATAAQAQTGP 787
Query: 501 RVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEIL--GQESVTAEKLPTPQEETSLTLC 558
+ EEE+DS E+ A P I L +ES PTP +T +
Sbjct: 788 EEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAA 847
Query: 559 ----PDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLS 614
D + EE D + +A I P D P S P +
Sbjct: 848 QAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVD---PNRSPAGPAATPAQAQAA 904
Query: 615 SAPKPVAA----ATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQA 670
S P+ A A S ++E+ +P +TP + + +A +A
Sbjct: 905 STPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIA--------- 955
Query: 671 EEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQD 730
P+ S + + +S K AT VS++ L L Q + L +
Sbjct: 956 ------PKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAA-----LKVLA 1004
Query: 731 TDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPK--PVAAATIVSQ 788
S A PVA S TLP S + + + T+ PK V AT +
Sbjct: 1005 QKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPE 1064
Query: 789 QAEEGLTLPQDSAMTP-----PLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMT 843
+++ S+ + P + P P T+V + A E +D +
Sbjct: 1065 SSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAES---SEDDVVA 1121
Query: 844 PPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAA 903
P L LS P TP + QA S TP L D+ S + A
Sbjct: 1122 PSQSL----LSGYMTP--GLTPANSQA---------SKATPKL---DSSPSVSSTLAAKD 1163
Query: 904 TPVSQQAEEGLTLPQDSA-MTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPVA 962
P +Q + PQ +A M +P T G E + TPQ + A +
Sbjct: 1164 DPDGKQEAK----PQQAAGMLSP-------KTGGKEAASGTTPQKSRKPKKGAGNPQAST 1212
Query: 963 TMAQQEVGEALGPRPAP-------------------EEKNAALPTVPEPAALD----QVQ 999
Q + + L +P P +E+ + T E + + +
Sbjct: 1213 LALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRK 1272
Query: 1000 QDDPQPAAEAGTPWA-AQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARA 1058
QPAA TP + ++ + G EA PE S + A+ G + +
Sbjct: 1273 LSGDQPAAR--TPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKG 1330
Query: 1059 HTGDGAKPDSPQKETLEVENQQEGG 1083
G D P++E + EGG
Sbjct: 1331 SLGSQGAKDEPEEELQKGMGTVEGG 1355
>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b [Homo
sapiens]
Length = 1411
Score = 79.0 bits (193), Expect = 3e-14
Identities = 197/952 (20%), Positives = 337/952 (35%), Gaps = 141/952 (14%)
Query: 510 ETDSTAGQESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLTLCPDSPQNLKEEG 569
E D+ + ++ P + E E E+ TA+ P S L D P ++KE+
Sbjct: 66 EEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKA 125
Query: 570 GLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQ 629
+ K +P A S +P + +P A T+VS+
Sbjct: 126 KAETEKAGK---TGNSMPHPATGKTVANLLSGKSP---------RKSAEPSANTTLVSET 173
Query: 630 AEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAAT----LVSQQAEEGLTLPQDSAMTPP 685
EEG ++P P + + S+ + ++++ + + +E+ L + SA
Sbjct: 174 EEEG-SVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKG 232
Query: 686 LPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATL 745
P + P P A V+ Q + G P++ + + + S + + AA
Sbjct: 233 TP----GKGATPAPPGKAGAVASQTKAG--KPEEDSES-----SSEESSDSEEETPAAKA 281
Query: 746 VSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPK----PVAAATIVSQQAEEGLTLPQDSA 801
+ Q G T +A P + AP P A ++ E+ + ++S
Sbjct: 282 LLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESD 341
Query: 802 MTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVA 861
P Q AP+ AA+ + +G P P + T P A
Sbjct: 342 SEEEAPAQAKPSGKAPQVRAASAPAKESPRKG---------AAPAPPRKTG------PAA 386
Query: 862 AATPVSQQAEEGLTLPQDSAMTPPLPLQDTDLSS-APKPVAAATPVSQQAEEGLTLPQDS 920
A V +Q E+ + ++S D+D + A A P+ + + P +
Sbjct: 387 AQVQVGKQEEDSRSSSEES---------DSDREALAAMNAAQVKPLGKSPQ---VKPAST 434
Query: 921 AMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAG---------------CAPGTEPVATMA 965
PL G +GP P P T A+ G + G P A
Sbjct: 435 MGMGPL-----GKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAP 489
Query: 966 QQE--VGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTL 1023
QE +G L +P P P A+ QV+ + P +E +++E +DS
Sbjct: 490 AQEKSLGNILQAKPTSSPAKGP-PQKAGPVAV-QVKAEKPMDNSE-----SSEESSDSAD 542
Query: 1024 GMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGG 1083
EA PA+ + AL P +AC + +T AK +P + + +
Sbjct: 543 SEEA-----PAAMTAAQAKPALKIPQTKAC-PKKTNTTASAKV-APVRVGTQAPRKAGTA 595
Query: 1084 LKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAV 1143
P G A+ G + P A ++ E S + E+ GL+ ++ +
Sbjct: 596 TSPA----GSSPAVAGGTQRP-AEDSSSSEESDSE-----EEKTGLAVTVGQAKSVGKGL 645
Query: 1144 ATEASLDSCPESSVGAVSSLDRG-CPDAPAPTSAPTSQ-QPEPVLGLGSVEQPHEVPSVL 1201
+A +SV SL +G P P T +Q + E S E+ +
Sbjct: 646 QVKA-------ASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAA 698
Query: 1202 GTPL---LQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAAL-------PPLEPPAPCLC 1251
+P + AK P+ SAPG + AA ++PP
Sbjct: 699 ASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPV---- 754
Query: 1252 QDPQEDSVEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLS-PHSPLLSPKV 1310
++PQ +V G +P V AA A +G + G+ S S + L+
Sbjct: 755 RNPQNSTVLAR---GPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVK 811
Query: 1311 ASMDAKDLALQILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSD 1370
S + + P + P +P G G SA + + +DS S + SD
Sbjct: 812 PSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDS--------GSSSEESD 863
Query: 1371 SHGESSAELDEQDILAPQTVQCPAQAPAGGSEETIAKAKQSRSEKKARKAMS 1422
S GE+ A + ++ P + G T A+A+ + + +KAR + S
Sbjct: 864 SDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASES 915
Score = 65.9 bits (159), Expect = 3e-10
Identities = 225/1047 (21%), Positives = 363/1047 (34%), Gaps = 205/1047 (19%)
Query: 406 SGEPHAQATLLQDSVQKTEEESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLSQRQELI 465
S EP A TL V +TEEE A G A+ G VS A +S+ + S ++
Sbjct: 160 SAEPSANTTL----VSETEEEGSVPAFGAAAKPGMVS--AGQADSSSEDTSSSSDETDVE 213
Query: 466 SEVTEEGLALGQEST-ATVTPH--TLQVAPGLQVEVATRVTPQAGEEETDSTAGQES--- 519
+ +E+ L + S A TP PG VA++ EE+++S++ + S
Sbjct: 214 VKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSE 273
Query: 520 ----AAMAMPQPSQEGISEILGQESVTAEK------LPTPQEETSLTLCPDSPQNLKEEG 569
AA A+ Q G + +G S A++ P P +T + +E
Sbjct: 274 EETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREE-- 331
Query: 570 GLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKP------VAAA 623
D S + + P QAK PQ A + P + +AP P AA
Sbjct: 332 --DSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAK-ESPRKGAAPAPPRKTGPAAAQ 388
Query: 624 TIVSQQAEEGLTLPQDS-----VMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQ 678
V +Q E+ + ++S + Q L +P+ A+T+ +G
Sbjct: 389 VQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVP 448
Query: 679 DSAMTPPLPL---------------QDTDLSSAPKPVAAATLVSQQAEEGLTLPQDS--A 721
+ P P + +D S P A A + L S A
Sbjct: 449 PGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPA 508
Query: 722 MTPPL-------------PLQDTDLS-----SAPKPVAAATLVSQQAEEGLTLPQDSAMT 763
PP P+ +++ S SA A A + + QA+ L +PQ A
Sbjct: 509 KGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACP 568
Query: 764 PPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPL------PLQDTDLS--- 814
+ T+ +++ K VA + +Q + T + +P + P +D+ S
Sbjct: 569 -----KKTNTTASAK-VAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEES 622
Query: 815 -SAPKPVAAATIVSQQAEEGLTLPQDSAMTPP-----------LP--------------L 848
S + A V Q G L +A P LP
Sbjct: 623 DSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQ 682
Query: 849 QDTDLSS--APKPVAAATPVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPV 906
+D++ S + AAA+P + T + + P +S+ K V AA
Sbjct: 683 EDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQA 742
Query: 907 SQQA----EEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGC-------- 954
Q++ + + PQ+S + A GP S P + A QA+ G
Sbjct: 743 KQRSPSKVKPPVRNPQNSTVLA------RGPASVPS-VGKAVATAAQAQTGPEEDSGSSE 795
Query: 955 --APGTEPVATMAQ-------QEVGEALGPRPAPEEKNAALPTVPE---PAALDQVQQDD 1002
+ E T+AQ ++ AL P K AA PT P P+A +QDD
Sbjct: 796 EESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAA-PTPPGKTGPSAAQAGKQDD 854
Query: 1003 PQPAAEAGTPWAAQEDADSTLGMEALSLPEPA--------SGAGEEI----AEALSRPGR 1050
++E + D ++ + + + +P S AG A+A S P +
Sbjct: 855 SGSSSEE-----SDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRK 909
Query: 1051 EACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAA 1110
E+ A + +S ++ + G++ +P A P
Sbjct: 910 ARASESTARSSSS---ESEDEDVIPATQCLTPGIRT------------NVVTMPTAHPRI 954
Query: 1111 CPEVSQARLLSPAREERGLSGKSTPEP----------TLP------SAVATEASLDSCPE 1154
P+ S A S R GK P +LP +A +AS P
Sbjct: 955 APKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPV 1014
Query: 1155 SSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLAK 1214
+ S +D PA + TS Q + G + +P ++P V + PE+
Sbjct: 1015 ARTQPSSGVDSAVGTLPATSPQSTSVQAK---GTNKLRKP-KLPEV--QQATKAPESSDD 1068
Query: 1215 GQPSTPVDRPLGPDPSAP-GTLAGAALPPLEPPAPCLCQDPQEDSVEDE--EPPGSLGLP 1271
+ S+ D P G + L P L ++ +S ED+ P SL
Sbjct: 1069 SEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLSG 1128
Query: 1272 PPQAGVQPAAAAVSGTTQPLGTGPRVS 1298
G+ PA + S T L + P VS
Sbjct: 1129 YMTPGLTPANSQASKATPKLDSSPSVS 1155
Score = 59.7 bits (143), Expect = 2e-08
Identities = 165/765 (21%), Positives = 271/765 (35%), Gaps = 134/765 (17%)
Query: 809 QDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAM-TPPLPLQDTDLSSAPKPVAAATPVS 867
+D L + V+ S+ +EE ++A TP L ++ + A P +
Sbjct: 67 EDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAK 126
Query: 868 QQAEE----GLTLPQDSA-MTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAM 922
+ E+ G ++P + T L + +P A T VS+ EEG ++P A
Sbjct: 127 AETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEG-SVPAFGAA 185
Query: 923 TAPLPL---------QDTGPTSGPEPLAV-ATPQTLQAEAGCAPGTEPVATMAQQEVGEA 972
P + +DT +S + V A+ + LQ A AP A+ G+
Sbjct: 186 AKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAP--------AKGTPGK- 236
Query: 973 LGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLPE 1032
G PAP K A+ + Q + P+ +E+ + ++ + + T +AL L
Sbjct: 237 -GATPAPPGKAGAVAS--------QTKAGKPEEDSESSSEESSDSE-EETPAAKAL-LQA 285
Query: 1033 PASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHG 1092
ASG ++ A S P +E+ + GA P P K V Q G + +Q
Sbjct: 286 KASGKTSQVGAA-SAPAKESPRK-------GAAPAPPGKTGPAVAKAQAGKREEDSQSSS 337
Query: 1093 PRSALGGAREVPDAPPAACPEVSQARLLSPAREE-RGLSGKSTPEPTLPSAVATEASLDS 1151
S P P+V A +PA+E R + + P T P+A +
Sbjct: 338 EESDSEEEAPAQAKPSGKAPQVRAAS--APAKESPRKGAAPAPPRKTGPAAAQVQVGKQE 395
Query: 1152 CPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPEN 1211
S S DR +A + Q +P LG +P ++P
Sbjct: 396 EDSRSSSEESDSDREA------LAAMNAAQVKP---LGK------------SPQVKPAST 434
Query: 1212 LAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGLP 1271
+ G P+ + GP P PG + P P A + +S +E S G
Sbjct: 435 MGMG----PLGKGAGPVP--PGKVG-----PATPSAQVGKWEEDSESSSEESSDSSDGEV 483
Query: 1272 PPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLALQILPPCQVPPP 1331
P V PA G +L K S AK
Sbjct: 484 P--TAVAPAQEKSLGN-----------------ILQAKPTSSPAK--------------- 509
Query: 1332 SGPQSPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELDEQDILAPQTVQ 1391
GP AGP + ++ ++S E S + S ++ +A + + PQT
Sbjct: 510 -GPPQKAGPVAVQVKAEKPMDNS--ESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKA 566
Query: 1392 CPAQAPAGGSEETIAKAKQSRSEKKARKAMSKLGLR-QIQGVTRITIQKSKNILFVIAKP 1450
CP + S + +++ +KA A S G + G T+ + S + ++
Sbjct: 567 CPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSS-----SEE 621
Query: 1451 DVFKSPASDTYVVFGEAKIEDLSQQVHKAAAEKFK----------VPSEPSALVPESAPR 1500
+ + V G+AK QV KAA+ K +P + V +
Sbjct: 622 SDSEEEKTGLAVTVGQAKSVGKGLQV-KAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAE 680
Query: 1501 PRVRLECKEEEEEEEEEVDEAGLELRDIELVMAQANVSRAKAVRA 1545
+ E EEE + EE ++ A+AN + A+A A
Sbjct: 681 KQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSA 725
Score = 55.8 bits (133), Expect = 3e-07
Identities = 169/805 (20%), Positives = 270/805 (33%), Gaps = 111/805 (13%)
Query: 328 PLSPEEEEEEAVADPDPGGDLAGEGEEDSTSASFLQSLSDL----SITEGMDEAFAFRDD 383
P EE+ ++ + G G+ S + + S+ +G +
Sbjct: 612 PAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTG 671
Query: 384 TSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSVQKTEEESGGGAKGLQAQDGTVS- 442
+ ++ +E+ +E S E A ++ SV+KT+ ++ A + GT+S
Sbjct: 672 PTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISA 731
Query: 443 --WAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQESTATVTPHTLQVAPGLQVEVAT 500
V AA Q R + + + LA G S +V VA Q +
Sbjct: 732 PGKVVTAAAQAKQRSP-SKVKPPVRNPQNSTVLARGPASVPSVGK---AVATAAQAQTGP 787
Query: 501 RVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEIL--GQESVTAEKLPTPQEETSLTLC 558
+ EEE+DS E+ A P I L +ES PTP +T +
Sbjct: 788 EEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAA 847
Query: 559 ----PDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLS 614
D + EE D + +A I P D P S P +
Sbjct: 848 QAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVD---PNRSPAGPAATPAQAQAA 904
Query: 615 SAPKPVAA----ATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSA-PK--PVAAATLVS 667
S P+ A A S ++E+ +P +TP + + +A P+ P A+ S
Sbjct: 905 STPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGAS 964
Query: 668 QQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLP 727
E P + + +S P AA +++Q+A E A T P
Sbjct: 965 SSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEA---QPPVARTQPSS 1021
Query: 728 LQDTDLSSAPKPVAAATLVSQQAEEGLTLPQ----DSAMTPPLPLQDTDLSSAPKPVAAA 783
D+ + + P +T V + L P+ A P D++ SS
Sbjct: 1022 GVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDS------ 1075
Query: 784 TIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMT 843
S +EE PQ + L P P T+V + A E +D +
Sbjct: 1076 ---SSGSEEDGEGPQGAKSAHTL---------GPTPSRTETLVEETAAES---SEDDVVA 1120
Query: 844 PPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAA 903
P L LS P TP + QA S TP L D+ S + A
Sbjct: 1121 PSQSL----LSGYMTP--GLTPANSQA---------SKATPKL---DSSPSVSSTLAAKD 1162
Query: 904 TPVSQQAEEGLTLPQDSA-MTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPVA 962
P +Q + PQ +A M +P T G E + TPQ + A +
Sbjct: 1163 DPDGKQEAK----PQQAAGMLSP-------KTGGKEAASGTTPQKSRKPKKGAGNPQAST 1211
Query: 963 TMAQQEVGEALGPRPAP-------------------EEKNAALPTVPEPAALD----QVQ 999
Q + + L +P P +E+ + T E + + +
Sbjct: 1212 LALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRK 1271
Query: 1000 QDDPQPAAEAGTPWA-AQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARA 1058
QPAA TP + ++ + G EA PE S + A+ G + +
Sbjct: 1272 LSGDQPAAR--TPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKG 1329
Query: 1059 HTGDGAKPDSPQKETLEVENQQEGG 1083
G D P++E + EGG
Sbjct: 1330 SLGSQGAKDEPEEELQKGMGTVEGG 1354
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
Length = 816
Score = 75.9 bits (185), Expect = 3e-13
Identities = 159/661 (24%), Positives = 210/661 (31%), Gaps = 95/661 (14%)
Query: 470 EEGLALGQEST-----ATVTPHTLQVAPGLQVEVA--TRVTPQAGEEETDSTAGQE---- 518
++GL + E T AT P ++ G + + + T TP AG E
Sbjct: 122 QKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLP 181
Query: 519 -SAAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGR 577
A A P+P EG + + S + P+P P + L+ L S
Sbjct: 182 RPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRR----PSAGGGLQRPASRSLSSSA 237
Query: 578 KPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVA-AATIVSQQAEEGLTL 636
P+++ A+ P + P LQ P AA + + L
Sbjct: 238 TPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLAT 297
Query: 637 PQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSA 696
P S PP P L + P P A QA L P A LP +
Sbjct: 298 PSPSA--PPSPSAPPSLQTLPSPPATPP---SQATTSLGSPTLQATHSFLPSPPLSPLAT 352
Query: 697 PKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATL---VSQQAEEG 753
P P A L A L P +PPL T AP +A L S
Sbjct: 353 PPPQAPPAL----ALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPP 408
Query: 754 LTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDL 813
+ P +PP+ T S AP +AA L +P +PP+ T
Sbjct: 409 VQAPFSPPASPPVSPSATPPSQAPPSLAAPP---------LQVPPSPPASPPMSPSATPP 459
Query: 814 SSAPKPVAAATIV----SQQAEEGLTLPQDSAMTPP---LPLQDTDLSSAPKPVAAATPV 866
AP P+AA + QA L P A+ P P Q SA P++
Sbjct: 460 PQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATP 519
Query: 867 SQQAEEGLTLPQ-------------DSAMTPPLPLQDTDLSS---------APKPVAAAT 904
QA L P + PP P DT +S P P + +
Sbjct: 520 PPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRS 579
Query: 905 PVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGT---EPV 961
P S + L SA + P L+ G SGPE A A+P A C P P
Sbjct: 580 PSSTLSGPDLAGHSSSATSTPEELR--GYDSGPEGGAAASPPPDAELAACHPAAWSRGPA 637
Query: 962 ATMAQQEVGEALGPRPAPE--------------EKNAALPTVPEPAALDQVQQDDPQPAA 1007
+A + G P P P E P P ALD P P
Sbjct: 638 PPLAFR--GAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALD----PGPSPGT 691
Query: 1008 EAGTPWAAQEDADSTLGMEALSLPEPASGA--GEEIAEALSRPGREACLEARAHTGDGAK 1065
G A S+ + L E GA + LSR A E A G G
Sbjct: 692 SGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAA-GGSGGG 750
Query: 1066 P 1066
P
Sbjct: 751 P 751
Score = 73.2 bits (178), Expect = 2e-12
Identities = 159/614 (25%), Positives = 212/614 (34%), Gaps = 116/614 (18%)
Query: 778 KPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQ--AEE--- 832
K AAA + +A LT + PP P+ L + + AA V ++ AE
Sbjct: 9 KAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAAL----RVLGAAGAVGRKPLAERAGG 64
Query: 833 --GLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLP-QDSAMTPPLPLQ 889
G T+P+ + P S + A P + ++ P + S T P PL
Sbjct: 65 IGGATIPESAPRAGPTRTSRPPASGRGE---RAPPAKNTSPGPVSSPGRASGTTRPGPLG 121
Query: 890 DTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQ 949
L + + A ++ P+ SA++A +GPT G TP
Sbjct: 122 QKGLRISAEETVARGKATEA-------PKRSALSAGARRDTSGPTPG-------TPSPAM 167
Query: 950 AEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEA 1009
A A GTE VG PRPAP +A P P V E
Sbjct: 168 ARRSRAAGTE---------VGL---PRPAP----SARPRPPTEGPRKSVSSASEHSTTE- 210
Query: 1010 GTPWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSP 1069
P A S G L PAS + A LS P R AR A P P
Sbjct: 211 --PSPAARRRPSAGG----GLQRPASRSLSSSATPLSSPARSGP-SARGTPRAPAHPSQP 263
Query: 1070 QKETLEVEN--QQEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSP----- 1122
+ + L+ Q K A GP S+ A P APP+ S L SP
Sbjct: 264 KPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPP 323
Query: 1123 --AREERG---------------LSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDR 1165
A G LS +TP P P A+A + +S L
Sbjct: 324 SQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLAT 383
Query: 1166 GCPDAPAPTS-----APTSQQPEPVLGLGSVEQPHEVP-----SVLGTPLLQPPENLAKG 1215
P AP + AP S P P V+ P P S TP Q P +LA
Sbjct: 384 PSPQAPNALAVHLLQAPFSPPPSP-----PVQAPFSPPASPPVSPSATPPSQAPPSLA-- 436
Query: 1216 QPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQA 1275
+ P+ P P P A ++ +A PP + P P PP L PPPQA
Sbjct: 437 --APPLQVP--PSPPASPPMSPSATPPPQAPPPLAA------------PPLQLAKPPPQA 480
Query: 1276 GVQPAAAAVSGTTQPLGTGP-RVSLSPHSPLLSPKVASMDAKDLALQILPPCQVPPPSGP 1334
A + P + P + SP + L +A+ + + P QV PPS P
Sbjct: 481 PPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQV-PPSPP 539
Query: 1335 QSPAGPQGLSAPEQ 1348
SP L AP +
Sbjct: 540 ASPT----LQAPRR 549
Score = 66.2 bits (160), Expect = 2e-10
Identities = 145/580 (25%), Positives = 190/580 (32%), Gaps = 86/580 (14%)
Query: 617 PKPVAAATIVSQQAEEGLTLPQDSVMT-PPLPLQDTELSSA-------PKPVAAATLVSQ 668
P P A + E GL P S PP +SSA P P A
Sbjct: 163 PSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRR---P 219
Query: 669 QAEEGLTLPQD---SAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPP 725
A GL P S+ PL SA A SQ +GL + +TPP
Sbjct: 220 SAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPP 279
Query: 726 LPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATI 785
D + A P++++ L + P SA PP P L + P P A
Sbjct: 280 RK----DAAPALGPLSSSPLAT---------PSPSA--PPSPSAPPSLQTLPSPPATPP- 323
Query: 786 VSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPP 845
QA L P A LP + P P A + A L P +PP
Sbjct: 324 --SQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPAL----ALPPLQAPPSPPASPP 377
Query: 846 LPLQDTDLSSAPKPVAA---ATPVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAA 902
L T AP +A P S + P +PP+ T S AP +AA
Sbjct: 378 LSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAA 437
Query: 903 -------ATPVSQQAEEGLTLPQDSA--MTAPLPLQDTGPTSGPEPLAVATP--QTLQAE 951
+ P S T P + + AP PLQ P P A+ATP Q L +
Sbjct: 438 PPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPP-ALATPPLQALPSP 495
Query: 952 AGCAPGTEPVATMAQQEVGEALGPRP-APEEKNAALPTVPEPAALDQVQQDDPQPAAEAG 1010
PG P + A + P P AP A L VP Q +P
Sbjct: 496 PASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRP----- 550
Query: 1011 TPWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQ 1070
P + + S + P P + LS P G + S
Sbjct: 551 -PTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDL---------AGHSSSATSTP 600
Query: 1071 KETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLS 1130
+E ++ EGG A PDA AAC + +R +P RG
Sbjct: 601 EELRGYDSGPEGG--------------AAASPPPDAELAACHPAAWSRGPAPPLAFRGAP 646
Query: 1131 GKSTPEP--TLPSAVATEASL--DSCPESSVGAVSSLDRG 1166
G P P T P + ++ PES+ A +LD G
Sbjct: 647 GAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPG 686
Score = 56.6 bits (135), Expect = 2e-07
Identities = 181/781 (23%), Positives = 243/781 (31%), Gaps = 119/781 (15%)
Query: 720 SAMTPPLPLQDTDLS-SAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPK 778
S T P PL L SA + VA L+ + P P P
Sbjct: 112 SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTP-------GTPS 164
Query: 779 PVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQ 838
P A + E GL P SA P P + S VS +E T P
Sbjct: 165 PAMARRSRAAGTEVGLPRPAPSARPRP-PTEGPRKS-----------VSSASEHSTTEPS 212
Query: 839 DSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPK 898
+A P ++ ++ATP+S A G + TP P + PK
Sbjct: 213 PAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG----PSARGTPRAPAHPSQ--PKPK 266
Query: 899 PVAAATPVSQQAEEGLTLPQDSAMTA--PL---PLQDTGPTSGPEPLAVATPQTLQAEAG 953
+ A P +T P+ A A PL PL P++ P P A + QTL +
Sbjct: 267 GLQALRPPQ------VTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPA 320
Query: 954 CAPG--TEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGT 1011
P T + + Q L P P P P AL +Q PA+ +
Sbjct: 321 TPPSQATTSLGSPTLQATHSFL-PSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLS 379
Query: 1012 PWAAQE-DADSTLGMEALSLP---EPASGAGEEIAEALSRPGREACLEARAHTGDGAKPD 1067
P A A + L + L P P+ + S P + A P
Sbjct: 380 PLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPP 439
Query: 1068 SPQKETLEVENQQEGGLKPLAQEHGPRSA--LGGAREVPDAPPAACPEVSQARLLSPARE 1125
+ P Q P +A L A+ P APPA QA L SP
Sbjct: 440 LQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQA-LPSPPAS 498
Query: 1126 ERG-----------LSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPT 1174
G +S +TP P P +A A L P S +S P P PT
Sbjct: 499 FPGQAPFSPSASLPMSPLATPPPQAPPVLA--APLLQVPPSPP---ASPTLQAPRRP-PT 552
Query: 1175 SAPTSQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGT 1234
P + P L L P PS + L P+ +T L S P
Sbjct: 553 PGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEG 612
Query: 1235 LAGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTG 1294
A A+ PP A C PAA + G PL
Sbjct: 613 GAAASPPPDAELAAC----------------------------HPAAWS-RGPAPPLA-- 641
Query: 1295 PRVSLSPHSPLLSPKVASMDAKDLALQILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDS 1354
+P +PL P + D C + GP+S G P
Sbjct: 642 --FRGAPGAPLPWPPATGPGSAD------GLCTIYETEGPESATPAPGALDPGPSPGTSG 693
Query: 1355 LEEDSPRALGSGQHSDSHGESSAELDE-----------QDILAPQTVQCPAQAPAGGSEE 1403
A G+G + S A L E Q +L+ + A+ AGGS
Sbjct: 694 ----GKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGG 749
Query: 1404 TIAKAKQSRSEKKARKAMSKLGLRQIQGVTRITIQKSKNILFVIA-KPDVFKSPASDTYV 1462
A+ AR A+S L + + + +I V + PD SP D V
Sbjct: 750 GPGGAEGGGVTGGARAALSDAELGRWAELLSPLDESRASITSVTSFSPDDVASPQGDWTV 809
Query: 1463 V 1463
V
Sbjct: 810 V 810
Score = 38.1 bits (87), Expect = 0.067
Identities = 76/342 (22%), Positives = 108/342 (31%), Gaps = 45/342 (13%)
Query: 27 DAAAATTILGGDRREPCALTPGPSHLALTF----------LPSK-PGARPQP-------- 67
+A + + G RR+ TPG A+ LP P ARP+P
Sbjct: 140 EAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKS 199
Query: 68 -EGASWDAGPGGAPSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIVMGEETC 126
AS + +P+A P GG LSS A +P + R
Sbjct: 200 VSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAH 259
Query: 127 QALLSPRAARTALRDQEGGHASPDPPPEL--CSQGDLSVPSP--PPDPDSFFTPPSTPTK 182
+ P+ + ALR + D P L S L+ PSP PP P + PPS T
Sbjct: 260 PSQPKPKGLQ-ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSA---PPSLQTL 315
Query: 183 TTYALLPACGPHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLAPA 242
+ P + L SPP SP + + A P + P+
Sbjct: 316 PSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQA----PPS 371
Query: 243 EGLDFPSGWGLSPQGSMVDERELHPAGTPEPPSSESSLSADSSSSWGQEGHFFDLDFLAN 302
P +P + +H P P + A S A+
Sbjct: 372 PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPP-------------AS 418
Query: 303 DPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEEAVADPDP 344
P+ P+A P Q ++V P P A P P
Sbjct: 419 PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP 460
Score = 38.1 bits (87), Expect = 0.067
Identities = 51/212 (24%), Positives = 75/212 (35%), Gaps = 32/212 (15%)
Query: 13 PEADRPGPRTDLSCDAAAATTILGGDRREPCALTPGPSHLALTFLPSKPGARPQPEGASW 72
P GPR +S + +TT P P A PS G +P S
Sbjct: 189 PRPPTEGPRKSVSSASEHSTT------------EPSP---AARRRPSAGGGLQRPASRSL 233
Query: 73 DAGPGGAPSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIVMGEETCQALLSP 132
+ + + + P GPS P + + L A P++ + L P
Sbjct: 234 SS----SATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP 289
Query: 133 RAARTALRDQEGGHASPDPPPELCSQGDLSVPSPPPDPDSFFTPP-STPT-KTTYALLPA 190
++ SP PP L ++PSPP P S T +PT + T++ LP+
Sbjct: 290 LSSSPLATPSPSAPPSPSAPPSL-----QTLPSPPATPPSQATTSLGSPTLQATHSFLPS 344
Query: 191 ------CGPHGDARDSEAELRDELLDSPPASP 216
P A + A + SPPASP
Sbjct: 345 PPLSPLATPPPQAPPALALPPLQAPPSPPASP 376
Score = 34.3 bits (77), Expect = 0.97
Identities = 74/262 (28%), Positives = 90/262 (34%), Gaps = 41/262 (15%)
Query: 31 ATTILGGDRREPCALTPGPSHLALTFLPSKPGARPQPEGASWDAGPG--GAPSAWADPGE 88
ATT LG T +H L P P A P P+ A P PS A P
Sbjct: 326 ATTSLGSP-------TLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPL 378
Query: 89 GGPSPMLLPEGLSSQALST---EAPLPATLEPRIVMGEETCQALLSPRAARTALRDQEGG 145
SP+ P + AL+ +AP P + QA SP A+
Sbjct: 379 ---SPLATPSPQAPNALAVHLLQAPFSPPPSPPV-------QAPFSPPASPPV-----SP 423
Query: 146 HASP--DPPPELCSQGDLSVPSPPPDPD---SFFTPPSTPTKTTYALLPACGPHGDARDS 200
A+P PP L + PSPP P S PP P L P A +
Sbjct: 424 SATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPA 483
Query: 201 EAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLAP----AEGLDFPSGWGLSPQ 256
A + L SPPAS G + S SP + AP A L P SP
Sbjct: 484 LATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPP----SPP 539
Query: 257 GSMVDERELHPAGTPEPPSSES 278
S + P TP P +S S
Sbjct: 540 ASPTLQAPRRPP-TPGPDTSVS 560
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.306 0.125 0.355
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 79,089,455
Number of Sequences: 37866
Number of extensions: 5252467
Number of successful extensions: 38999
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 161
Number of HSP's successfully gapped in prelim test: 1773
Number of HSP's that attempted gapping in prelim test: 21612
Number of HSP's gapped (non-prelim): 13739
length of query: 1562
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1446
effective length of database: 13,855,062
effective search space: 20034419652
effective search space used: 20034419652
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.