Guide to the Human Genome
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Search of human proteins with 116292750

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|116292750 lipoprotein Lp(a) precursor [Homo sapiens]
         (2040 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|116292750 lipoprotein Lp(a) precursor [Homo sapiens]              4453   0.0  
gi|4505881 plasminogen [Homo sapiens]                                1078   0.0  
gi|205277383 macrophage stimulating 1 (hepatocyte growth factor-...   465   e-130
gi|33859835 hepatocyte growth factor isoform 1 preproprotein [Ho...   449   e-125
gi|58533170 hepatocyte growth factor isoform 3 precursor [Homo s...   442   e-123
gi|239743017 PREDICTED: hypothetical protein XP_002342719 [Homo ...   294   5e-79
gi|4503635 coagulation factor II preproprotein [Homo sapiens]         238   6e-62
gi|4505861 plasminogen activator, tissue isoform 1 preproprotein...   236   2e-61
gi|14702169 plasminogen activator, tissue isoform 3 preproprotei...   236   2e-61
gi|22035663 lipoprotein, Lp(a)-like 2 precursor [Homo sapiens]        210   1e-53
gi|13346502 lipoprotein, Lp(a)-like 2 precursor [Homo sapiens]        210   1e-53
gi|4758502 hyaluronan binding protein 2 preproprotein [Homo sapi...   191   5e-48
gi|4504383 HGF activator preproprotein [Homo sapiens]                 185   3e-46
gi|58533163 hepatocyte growth factor isoform 2 precursor [Homo s...   184   8e-46
gi|110815798 ovochymase 1 [Homo sapiens]                              178   4e-44
gi|116256363 transmembrane protease, serine 13 [Homo sapiens]         177   9e-44
gi|58533165 hepatocyte growth factor isoform 4 precursor [Homo s...   177   1e-43
gi|156938340 transmembrane tryptase preproprotein [Homo sapiens]      177   1e-43
gi|13994276 marapsin [Homo sapiens]                                   173   1e-42
gi|117956391 protease, serine, 33 [Homo sapiens]                      173   2e-42
gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo sap...   172   4e-42
gi|33695155 hepsin [Homo sapiens]                                     171   9e-42
gi|4504481 hepsin [Homo sapiens]                                      171   9e-42
gi|222537759 plasminogen activator, urokinase isoform 2 [Homo sa...   169   2e-41
gi|4505863 plasminogen activator, urokinase isoform 1 preproprot...   169   2e-41
gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo sa...   168   4e-41
gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo sa...   168   4e-41
gi|118498341 chymotrypsin B1 [Homo sapiens]                           167   7e-41
gi|21614531 testisin isoform 2 [Homo sapiens]                         167   7e-41
gi|5803197 testisin isoform 1 [Homo sapiens]                          166   2e-40

>gi|116292750 lipoprotein Lp(a) precursor [Homo sapiens]
          Length = 2040

 Score = 4453 bits (11550), Expect = 0.0
 Identities = 2040/2040 (100%), Positives = 2040/2040 (100%)

Query: 1    MEHKEVVLLLLLFLKSAAPEQSHVVQDCYHGDGQSYRGTYSTTVTGRTCQAWSSMTPHQH 60
            MEHKEVVLLLLLFLKSAAPEQSHVVQDCYHGDGQSYRGTYSTTVTGRTCQAWSSMTPHQH
Sbjct: 1    MEHKEVVLLLLLFLKSAAPEQSHVVQDCYHGDGQSYRGTYSTTVTGRTCQAWSSMTPHQH 60

Query: 61   NRTTENYPNAGLIMNYCRNPDAVAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTP 120
            NRTTENYPNAGLIMNYCRNPDAVAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTP
Sbjct: 61   NRTTENYPNAGLIMNYCRNPDAVAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTP 120

Query: 121  VPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEY 180
            VPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEY
Sbjct: 121  VPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEY 180

Query: 181  YPNAGLIMNYCRNPDAVAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEA 240
            YPNAGLIMNYCRNPDAVAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEA
Sbjct: 181  YPNAGLIMNYCRNPDAVAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEA 240

Query: 241  PSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGL 300
            PSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGL
Sbjct: 241  PSEQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGL 300

Query: 301  IMNYCRNPDAVAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAP 360
            IMNYCRNPDAVAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAP
Sbjct: 301  IMNYCRNPDAVAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAP 360

Query: 361  TEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCR 420
            TEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCR
Sbjct: 361  TEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCR 420

Query: 421  NPDAVAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 480
            NPDAVAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG
Sbjct: 421  NPDAVAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 480

Query: 481  VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 540
            VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA
Sbjct: 481  VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 540

Query: 541  APYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYH 600
            APYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYH
Sbjct: 541  APYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYH 600

Query: 601  GNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYT 660
            GNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYT
Sbjct: 601  GNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYT 660

Query: 661  RDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSY 720
            RDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSY
Sbjct: 661  RDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSY 720

Query: 721  RGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYTRDPGVR 780
            RGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYTRDPGVR
Sbjct: 721  RGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYTRDPGVR 780

Query: 781  WEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYST 840
            WEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYST
Sbjct: 781  WEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYST 840

Query: 841  TVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDPVAAPYCYTRDPSVRWEYCNL 900
            TVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDPVAAPYCYTRDPSVRWEYCNL
Sbjct: 841  TVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDPVAAPYCYTRDPSVRWEYCNL 900

Query: 901  TQCSDAEGTAVAPPTITPIPSLEAPSEQAPTEQRPGVQECYHGNGQSYQGTYFITVTGRT 960
            TQCSDAEGTAVAPPTITPIPSLEAPSEQAPTEQRPGVQECYHGNGQSYQGTYFITVTGRT
Sbjct: 901  TQCSDAEGTAVAPPTITPIPSLEAPSEQAPTEQRPGVQECYHGNGQSYQGTYFITVTGRT 960

Query: 961  CQAWSSMTPHSHSRTPAYYPNAGLIKNYCRNPDPVAAPWCYTTDPSVRWEYCNLTRCSDA 1020
            CQAWSSMTPHSHSRTPAYYPNAGLIKNYCRNPDPVAAPWCYTTDPSVRWEYCNLTRCSDA
Sbjct: 961  CQAWSSMTPHSHSRTPAYYPNAGLIKNYCRNPDPVAAPWCYTTDPSVRWEYCNLTRCSDA 1020

Query: 1021 EWTAFVPPNVILAPSLEAFFEQALTEETPGVQDCYYHYGQSYRGTYSTTVTGRTCQAWSS 1080
            EWTAFVPPNVILAPSLEAFFEQALTEETPGVQDCYYHYGQSYRGTYSTTVTGRTCQAWSS
Sbjct: 1021 EWTAFVPPNVILAPSLEAFFEQALTEETPGVQDCYYHYGQSYRGTYSTTVTGRTCQAWSS 1080

Query: 1081 MTPHQHSRTPENYPNAGLTRNYCRNPDAEIRPWCYTMDPSVRWEYCNLTQCLVTESSVLA 1140
            MTPHQHSRTPENYPNAGLTRNYCRNPDAEIRPWCYTMDPSVRWEYCNLTQCLVTESSVLA
Sbjct: 1081 MTPHQHSRTPENYPNAGLTRNYCRNPDAEIRPWCYTMDPSVRWEYCNLTQCLVTESSVLA 1140

Query: 1141 TLTVVPDPSTEASSEEAPTEQSPGVQDCYHGDGQSYRGSFSTTVTGRTCQSWSSMTPHWH 1200
            TLTVVPDPSTEASSEEAPTEQSPGVQDCYHGDGQSYRGSFSTTVTGRTCQSWSSMTPHWH
Sbjct: 1141 TLTVVPDPSTEASSEEAPTEQSPGVQDCYHGDGQSYRGSFSTTVTGRTCQSWSSMTPHWH 1200

Query: 1201 QRTTEYYPNGGLTRNYCRNPDAEISPWCYTMDPNVRWEYCNLTQCPVTESSVLATSTAVS 1260
            QRTTEYYPNGGLTRNYCRNPDAEISPWCYTMDPNVRWEYCNLTQCPVTESSVLATSTAVS
Sbjct: 1201 QRTTEYYPNGGLTRNYCRNPDAEISPWCYTMDPNVRWEYCNLTQCPVTESSVLATSTAVS 1260

Query: 1261 EQAPTEQSPTVQDCYHGDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTR 1320
            EQAPTEQSPTVQDCYHGDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTR
Sbjct: 1261 EQAPTEQSPTVQDCYHGDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTR 1320

Query: 1321 NYCRNPDAEIRPWCYTMDPSVRWEYCNLTQCPVMESTLLTTPTVVPVPSTELPSEEAPTE 1380
            NYCRNPDAEIRPWCYTMDPSVRWEYCNLTQCPVMESTLLTTPTVVPVPSTELPSEEAPTE
Sbjct: 1321 NYCRNPDAEIRPWCYTMDPSVRWEYCNLTQCPVMESTLLTTPTVVPVPSTELPSEEAPTE 1380

Query: 1381 NSTGVQDCYRGDGQSYRGTLSTTITGRTCQSWSSMTPHWHRRIPLYYPNAGLTRNYCRNP 1440
            NSTGVQDCYRGDGQSYRGTLSTTITGRTCQSWSSMTPHWHRRIPLYYPNAGLTRNYCRNP
Sbjct: 1381 NSTGVQDCYRGDGQSYRGTLSTTITGRTCQSWSSMTPHWHRRIPLYYPNAGLTRNYCRNP 1440

Query: 1441 DAEIRPWCYTMDPSVRWEYCNLTRCPVTESSVLTTPTVAPVPSTEAPSEQAPPEKSPVVQ 1500
            DAEIRPWCYTMDPSVRWEYCNLTRCPVTESSVLTTPTVAPVPSTEAPSEQAPPEKSPVVQ
Sbjct: 1441 DAEIRPWCYTMDPSVRWEYCNLTRCPVTESSVLTTPTVAPVPSTEAPSEQAPPEKSPVVQ 1500

Query: 1501 DCYHGDGRSYRGISSTTVTGRTCQSWSSMIPHWHQRTPENYPNAGLTENYCRNPDSGKQP 1560
            DCYHGDGRSYRGISSTTVTGRTCQSWSSMIPHWHQRTPENYPNAGLTENYCRNPDSGKQP
Sbjct: 1501 DCYHGDGRSYRGISSTTVTGRTCQSWSSMIPHWHQRTPENYPNAGLTENYCRNPDSGKQP 1560

Query: 1561 WCYTTDPCVRWEYCNLTQCSETESGVLETPTVVPVPSMEAHSEAAPTEQTPVVRQCYHGN 1620
            WCYTTDPCVRWEYCNLTQCSETESGVLETPTVVPVPSMEAHSEAAPTEQTPVVRQCYHGN
Sbjct: 1561 WCYTTDPCVRWEYCNLTQCSETESGVLETPTVVPVPSMEAHSEAAPTEQTPVVRQCYHGN 1620

Query: 1621 GQSYRGTFSTTVTGRTCQSWSSMTPHRHQRTPENYPNDGLTMNYCRNPDADTGPWCFTMD 1680
            GQSYRGTFSTTVTGRTCQSWSSMTPHRHQRTPENYPNDGLTMNYCRNPDADTGPWCFTMD
Sbjct: 1621 GQSYRGTFSTTVTGRTCQSWSSMTPHRHQRTPENYPNDGLTMNYCRNPDADTGPWCFTMD 1680

Query: 1681 PSIRWEYCNLTRCSDTEGTVVAPPTVIQVPSLGPPSEQDCMFGNGKGYRGKKATTVTGTP 1740
            PSIRWEYCNLTRCSDTEGTVVAPPTVIQVPSLGPPSEQDCMFGNGKGYRGKKATTVTGTP
Sbjct: 1681 PSIRWEYCNLTRCSDTEGTVVAPPTVIQVPSLGPPSEQDCMFGNGKGYRGKKATTVTGTP 1740

Query: 1741 CQEWAAQEPHRHSTFIPGTNKWAGLEKNYCRNPDGDINGPWCYTMNPRKLFDYCDIPLCA 1800
            CQEWAAQEPHRHSTFIPGTNKWAGLEKNYCRNPDGDINGPWCYTMNPRKLFDYCDIPLCA
Sbjct: 1741 CQEWAAQEPHRHSTFIPGTNKWAGLEKNYCRNPDGDINGPWCYTMNPRKLFDYCDIPLCA 1800

Query: 1801 SSSFDCGKPQVEPKKCPGSIVGGCVAHPHSWPWQVSLRTRFGKHFCGGTLISPEWVLTAA 1860
            SSSFDCGKPQVEPKKCPGSIVGGCVAHPHSWPWQVSLRTRFGKHFCGGTLISPEWVLTAA
Sbjct: 1801 SSSFDCGKPQVEPKKCPGSIVGGCVAHPHSWPWQVSLRTRFGKHFCGGTLISPEWVLTAA 1860

Query: 1861 HCLKKSSRPSSYKVILGAHQEVNLESHVQEIEVSRLFLEPTQADIALLKLSRPAVITDKV 1920
            HCLKKSSRPSSYKVILGAHQEVNLESHVQEIEVSRLFLEPTQADIALLKLSRPAVITDKV
Sbjct: 1861 HCLKKSSRPSSYKVILGAHQEVNLESHVQEIEVSRLFLEPTQADIALLKLSRPAVITDKV 1920

Query: 1921 MPACLPSPDYMVTARTECYITGWGETQGTFGTGLLKEAQLLVIENEVCNHYKYICAEHLA 1980
            MPACLPSPDYMVTARTECYITGWGETQGTFGTGLLKEAQLLVIENEVCNHYKYICAEHLA
Sbjct: 1921 MPACLPSPDYMVTARTECYITGWGETQGTFGTGLLKEAQLLVIENEVCNHYKYICAEHLA 1980

Query: 1981 RGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYARVSRFVTWIEGMMRNN 2040
            RGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYARVSRFVTWIEGMMRNN
Sbjct: 1981 RGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYARVSRFVTWIEGMMRNN 2040


>gi|4505881 plasminogen [Homo sapiens]
          Length = 810

 Score = 1078 bits (2789), Expect = 0.0
 Identities = 501/785 (63%), Positives = 576/785 (73%), Gaps = 79/785 (10%)

Query: 1266 EQSPTVQDCYHGDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRN 1325
            E+   + +C  G+G++YRG+ S T  G TCQ WSS +PH  + +   +P+ GL  NYCRN
Sbjct: 95   EKKVYLSECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENYCRN 154

Query: 1326 PDAEIR-PWCYTMDPSVRWEYCNLTQCPVMESTLLTTPTVVPVPSTELPSEEAPTENSTG 1384
            PD + + PWCYT DP  R++YC++ +C                                 
Sbjct: 155  PDNDPQGPWCYTTDPEKRYDYCDILECE-------------------------------- 182

Query: 1385 VQDCYRGDGQSYRGTLSTTITGRTCQSWSSMTPHWHRRIPLYYPNAGLTRNYCRNPDAEI 1444
             ++C    G++Y G +S T++G  CQ+W S +PH H  IP  +PN  L +NYCRNPD E+
Sbjct: 183  -EECMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPDREL 241

Query: 1445 RPWCYTMDPSVRWEYCNLTRCPVTESSVLTTPTVAPVPSTEAPSEQAPPEKSPVVQDCYH 1504
            RPWC+T DP+ RWE C++ RC        TTP               PP   P  Q C  
Sbjct: 242  RPWCFTTDPNKRWELCDIPRC--------TTP---------------PPSSGPTYQ-CLK 277

Query: 1505 GDGRSYRGISSTTVTGRTCQSWSSMIPHWHQRTPENYPNAGLTENYCRNPDSGKQPWCYT 1564
            G G +YRG  + TV+G TCQ WS+  PH H RTPEN+P   L ENYCRNPD  + PWC+T
Sbjct: 278  GTGENYRGNVAVTVSGHTCQHWSAQTPHTHNRTPENFPCKNLDENYCRNPDGKRAPWCHT 337

Query: 1565 TDPCVRWEYCNLTQCSETESGVLETPTVVPVPSMEAHSEAAPTEQTPVVRQCYHGNGQSY 1624
            T+  VRWEYC +  C  +           PV S E  +  AP E TPVV+ CYHG+GQSY
Sbjct: 338  TNSQVRWEYCKIPSCDSS-----------PV-STEQLAPTAPPELTPVVQDCYHGDGQSY 385

Query: 1625 RGTFSTTVTGRTCQSWSSMTPHRHQRTPENYPNDGLTMNYCRNPDADTGPWCFTMDPSIR 1684
            RGT STT TG+ CQSWSSMTPHRHQ+TPENYPN GLTMNYCRNPDAD GPWCFT DPS+R
Sbjct: 386  RGTSSTTTTGKKCQSWSSMTPHRHQKTPENYPNAGLTMNYCRNPDADKGPWCFTTDPSVR 445

Query: 1685 WEYCNLTRCSDTEGTVVAPPTVIQVPSLGPPSEQDCMFGNGKGYRGKKATTVTGTPCQEW 1744
            WEYCNL +CS TE +VVAPP V+ +P +  PSE+DCMFGNGKGYRGK+ATTVTGTPCQ+W
Sbjct: 446  WEYCNLKKCSGTEASVVAPPPVVLLPDVETPSEEDCMFGNGKGYRGKRATTVTGTPCQDW 505

Query: 1745 AAQEPHRHSTFIPGTNKWAGLEKNYCRNPDGDINGPWCYTMNPRKLFDYCDIPLCASSSF 1804
            AAQEPHRHS F P TN  AGLEKNYCRNPDGD+ GPWCYT NPRKL+DYCD+P CA+ SF
Sbjct: 506  AAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDVGGPWCYTTNPRKLYDYCDVPQCAAPSF 565

Query: 1805 DCGKPQVEPKKCPGSIVGGCVAHPHSWPWQVSLRTRFGKHFCGGTLISPEWVLTAAHCLK 1864
            DCGKPQVEPKKCPG +VGGCVAHPHSWPWQVSLRTRFG HFCGGTLISPEWVLTAAHCL+
Sbjct: 566  DCGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLE 625

Query: 1865 KSSRPSSYKVILGAHQEVNLESHVQEIEVSRLFLEPTQADIALLKLSRPAVITDKVMPAC 1924
            KS RPSSYKVILGAHQEVNLE HVQEIEVSRLFLEPT+ DIALLKLS PAVITDKV+PAC
Sbjct: 626  KSPRPSSYKVILGAHQEVNLEPHVQEIEVSRLFLEPTRKDIALLKLSSPAVITDKVIPAC 685

Query: 1925 LPSPDYMVTARTECYITGWGETQGTFGTGLLKEAQLLVIENEVCNHYKY---------IC 1975
            LPSP+Y+V  RTEC+ITGWGETQGTFG GLLKEAQL VIEN+VCN Y++         +C
Sbjct: 686  LPSPNYVVADRTECFITGWGETQGTFGAGLLKEAQLPVIENKVCNRYEFLNGRVQSTELC 745

Query: 1976 AEHLARGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYARVSRFVTWIEG 2035
            A HLA GTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVY RVSRFVTWIEG
Sbjct: 746  AGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTWIEG 805

Query: 2036 MMRNN 2040
            +MRNN
Sbjct: 806  VMRNN 810



 Score =  536 bits (1381), Expect = e-152
 Identities = 251/538 (46%), Positives = 325/538 (60%), Gaps = 74/538 (13%)

Query: 1160 EQSPGVQDCYHGDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRN 1219
            E+   + +C  G+G++YRG+ S T  G TCQ WSS +PH  + +   +P+ GL  NYCRN
Sbjct: 95   EKKVYLSECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENYCRN 154

Query: 1220 PDAE-ISPWCYTMDPNVRWEYCNLTQCPVTESSVLATSTAVSEQAPTEQSPTVQDCYHGD 1278
            PD +   PWCYT DP  R++YC++ +C                          ++C H  
Sbjct: 155  PDNDPQGPWCYTTDPEKRYDYCDILECE-------------------------EECMHCS 189

Query: 1279 GQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRNPDAEIRPWCYTMD 1338
            G++Y G  S T++G  CQ+W S +PH H      +PN  L +NYCRNPD E+RPWC+T D
Sbjct: 190  GENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPDRELRPWCFTTD 249

Query: 1339 PSVRWEYCNLTQCPVMESTLLTTPTVVPVPSTELPSEEAPTENSTGVQDCYRGDGQSYRG 1398
            P+ RWE C++ +C        TTP          P    PT        C +G G++YRG
Sbjct: 250  PNKRWELCDIPRC--------TTP----------PPSSGPT------YQCLKGTGENYRG 285

Query: 1399 TLSTTITGRTCQSWSSMTPHWHRRIPLYYPNAGLTRNYCRNPDAEIRPWCYTMDPSVRWE 1458
             ++ T++G TCQ WS+ TPH H R P  +P   L  NYCRNPD +  PWC+T +  VRWE
Sbjct: 286  NVAVTVSGHTCQHWSAQTPHTHNRTPENFPCKNLDENYCRNPDGKRAPWCHTTNSQVRWE 345

Query: 1459 YCNLTRCPVTESSVLTTPTVAPVPSTEAPSEQAPPEKSPVVQDCYHGDGRSYRGISSTTV 1518
            YC +  C   +SS ++T  +AP          APPE +PVVQDCYHGDG+SYRG SSTT 
Sbjct: 346  YCKIPSC---DSSPVSTEQLAPT---------APPELTPVVQDCYHGDGQSYRGTSSTTT 393

Query: 1519 TGRTCQSWSSMIPHWHQRTPENYPNAGLTENYCRNPDSGKQPWCYTTDPCVRWEYCNLTQ 1578
            TG+ CQSWSSM PH HQ+TPENYPNAGLT NYCRNPD+ K PWC+TTDP VRWEYCNL +
Sbjct: 394  TGKKCQSWSSMTPHRHQKTPENYPNAGLTMNYCRNPDADKGPWCFTTDPSVRWEYCNLKK 453

Query: 1579 CSETESGVLETPTVVPVPSMEAHSEAAPTEQTPVVRQCYHGNGQSYRGTFSTTVTGRTCQ 1638
            CS TE+ V+  P VV +P +E          TP    C  GNG+ YRG  +TTVTG  CQ
Sbjct: 454  CSGTEASVVAPPPVVLLPDVE----------TPSEEDCMFGNGKGYRGKRATTVTGTPCQ 503

Query: 1639 SWSSMTPHRHQ-RTPENYPNDGLTMNYCRNPDADT-GPWCFTMDPSIRWEYCNLTRCS 1694
             W++  PHRH   TPE  P  GL  NYCRNPD D  GPWC+T +P   ++YC++ +C+
Sbjct: 504  DWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDVGGPWCYTTNPRKLYDYCDVPQCA 561



 Score =  526 bits (1354), Expect = e-148
 Identities = 256/576 (44%), Positives = 334/576 (57%), Gaps = 90/576 (15%)

Query: 932  EQRPGVQECYHGNGQSYQGTYFITVTGRTCQAWSSMTPHSHSRTPAYYPNAGLIKNYCRN 991
            E++  + EC  GNG++Y+GT   T  G TCQ WSS +PH    +PA +P+ GL +NYCRN
Sbjct: 95   EKKVYLSECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENYCRN 154

Query: 992  PD-PVAAPWCYTTDPSVRWEYCNLTRCSDAEWTAFVPPNVILAPSLEAFFEQALTEETPG 1050
            PD     PWCYTTDP  R++YC++  C +                               
Sbjct: 155  PDNDPQGPWCYTTDPEKRYDYCDILECEE------------------------------- 183

Query: 1051 VQDCYYHYGQSYRGTYSTTVTGRTCQAWSSMTPHQHSRTPENYPNAGLTRNYCRNPDAEI 1110
              +C +  G++Y G  S T++G  CQAW S +PH H   P  +PN  L +NYCRNPD E+
Sbjct: 184  --ECMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPDREL 241

Query: 1111 RPWCYTMDPSVRWEYCNLTQCLVTESSVLATLTVVPDPSTEASSEEAPTEQSPGVQDCYH 1170
            RPWC+T DP+ RWE C++ +C              P PS+       PT Q      C  
Sbjct: 242  RPWCFTTDPNKRWELCDIPRC------------TTPPPSS------GPTYQ------CLK 277

Query: 1171 GDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRNPDAEISPWCYT 1230
            G G++YRG+ + TV+G TCQ WS+ TPH H RT E +P   L  NYCRNPD + +PWC+T
Sbjct: 278  GTGENYRGNVAVTVSGHTCQHWSAQTPHTHNRTPENFPCKNLDENYCRNPDGKRAPWCHT 337

Query: 1231 MDPNVRWEYCNLTQCPVTESSVLATSTAVSEQAPTEQSPTVQDCYHGDGQSYRGSFSTTV 1290
             +  VRWEYC +  C   +SS ++T   ++  AP E +P VQDCYHGDGQSYRG+ STT 
Sbjct: 338  TNSQVRWEYCKIPSC---DSSPVSTEQ-LAPTAPPELTPVVQDCYHGDGQSYRGTSSTTT 393

Query: 1291 TGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRNPDAEIRPWCYTMDPSVRWEYCNLTQ 1350
            TG+ CQSWSSMTPH HQ+T E YPN GLT NYCRNPDA+  PWC+T DPSVRWEYCNL +
Sbjct: 394  TGKKCQSWSSMTPHRHQKTPENYPNAGLTMNYCRNPDADKGPWCFTTDPSVRWEYCNLKK 453

Query: 1351 CPVMESTLLTTPTVVPVPSTELPSEEAPTENSTGVQDCYRGDGQSYRGTLSTTITGRTCQ 1410
            C   E++++  P VV +P  E PSEE          DC  G+G+ YRG  +TT+TG  CQ
Sbjct: 454  CSGTEASVVAPPPVVLLPDVETPSEE----------DCMFGNGKGYRGKRATTVTGTPCQ 503

Query: 1411 SWSSMTPHWHRRI-PLYYPNAGLTRNYCRNPDAEI-RPWCYTMDPSVRWEYCNLTRCPVT 1468
             W++  PH H    P   P AGL +NYCRNPD ++  PWCYT +P   ++YC++ +C   
Sbjct: 504  DWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDVGGPWCYTTNPRKLYDYCDVPQC--- 560

Query: 1469 ESSVLTTPTVAPVPSTEAPSEQAPPEKSP--VVQDC 1502
                         PS +    Q  P+K P  VV  C
Sbjct: 561  -----------AAPSFDCGKPQVEPKKCPGRVVGGC 585



 Score =  515 bits (1327), Expect = e-145
 Identities = 246/540 (45%), Positives = 317/540 (58%), Gaps = 74/540 (13%)

Query: 1044 LTEETPGVQDCYYHYGQSYRGTYSTTVTGRTCQAWSSMTPHQHSRTPENYPNAGLTRNYC 1103
            L E+   + +C    G++YRGT S T  G TCQ WSS +PH+   +P  +P+ GL  NYC
Sbjct: 93   LFEKKVYLSECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENYC 152

Query: 1104 RNPDAEIR-PWCYTMDPSVRWEYCNLTQCLVTESSVLATLTVVPDPSTEASSEEAPTEQS 1162
            RNPD + + PWCYT DP  R++YC++ +C                               
Sbjct: 153  RNPDNDPQGPWCYTTDPEKRYDYCDILEC------------------------------- 181

Query: 1163 PGVQDCYHGDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRNPDA 1222
               ++C H  G++Y G  S T++G  CQ+W S +PH H      +PN  L +NYCRNPD 
Sbjct: 182  --EEECMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPDR 239

Query: 1223 EISPWCYTMDPNVRWEYCNLTQCPVTESSVLATSTAVSEQAPTEQSPTVQDCYHGDGQSY 1282
            E+ PWC+T DPN RWE C++ +C                  P    PT Q C  G G++Y
Sbjct: 240  ELRPWCFTTDPNKRWELCDIPRCTT---------------PPPSSGPTYQ-CLKGTGENY 283

Query: 1283 RGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRNPDAEIRPWCYTMDPSVR 1342
            RG+ + TV+G TCQ WS+ TPH H RT E +P   L  NYCRNPD +  PWC+T +  VR
Sbjct: 284  RGNVAVTVSGHTCQHWSAQTPHTHNRTPENFPCKNLDENYCRNPDGKRAPWCHTTNSQVR 343

Query: 1343 WEYCNLTQCPVMESTLLTTPTVVPVPSTELPSEEAPTENSTGVQDCYRGDGQSYRGTLST 1402
            WEYC +  C   +S+ ++T  + P          AP E +  VQDCY GDGQSYRGT ST
Sbjct: 344  WEYCKIPSC---DSSPVSTEQLAPT---------APPELTPVVQDCYHGDGQSYRGTSST 391

Query: 1403 TITGRTCQSWSSMTPHWHRRIPLYYPNAGLTRNYCRNPDAEIRPWCYTMDPSVRWEYCNL 1462
            T TG+ CQSWSSMTPH H++ P  YPNAGLT NYCRNPDA+  PWC+T DPSVRWEYCNL
Sbjct: 392  TTTGKKCQSWSSMTPHRHQKTPENYPNAGLTMNYCRNPDADKGPWCFTTDPSVRWEYCNL 451

Query: 1463 TRCPVTESSVLTTPTVAPVPSTEAPSEQAPPEKSPVVQDCYHGDGRSYRGISSTTVTGRT 1522
             +C  TE+SV+  P V  +P  E PSE          +DC  G+G+ YRG  +TTVTG  
Sbjct: 452  KKCSGTEASVVAPPPVVLLPDVETPSE----------EDCMFGNGKGYRGKRATTVTGTP 501

Query: 1523 CQSWSSMIPHWHQ-RTPENYPNAGLTENYCRNPDSG-KQPWCYTTDPCVRWEYCNLTQCS 1580
            CQ W++  PH H   TPE  P AGL +NYCRNPD     PWCYTT+P   ++YC++ QC+
Sbjct: 502  CQDWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDVGGPWCYTTNPRKLYDYCDVPQCA 561



 Score =  514 bits (1325), Expect = e-145
 Identities = 256/560 (45%), Positives = 324/560 (57%), Gaps = 83/560 (14%)

Query: 134 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 193
           E++  + EC  GNG++YRGT S T  G TCQ WSS +PH    +P  +P+ GL  NYCRN
Sbjct: 95  EKKVYLSECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENYCRN 154

Query: 194 PDA-VAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 252
           PD     P+CYT DP  R++YC++ +C +                               
Sbjct: 155 PDNDPQGPWCYTTDPEKRYDYCDILECEE------------------------------- 183

Query: 253 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 312
             EC H +G++Y G  S T++G  CQAW S +PH+H   P  +PN  L  NYCRNPD   
Sbjct: 184 --ECMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPDREL 241

Query: 313 APYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYH 372
            P+C+T DP  RWE C++ +C+            TP PS        PT Q      C  
Sbjct: 242 RPWCFTTDPNKRWELCDIPRCT------------TPPPS------SGPTYQ------CLK 277

Query: 373 GNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYT 432
           G G++YRG  + TV+G TCQ WS+ TPH+H+RTPE +P   L  NYCRNPD   AP+C+T
Sbjct: 278 GTGENYRGNVAVTVSGHTCQHWSAQTPHTHNRTPENFPCKNLDENYCRNPDGKRAPWCHT 337

Query: 433 RDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSY 492
            +  VRWEYC +  C  +           PV S E  +  AP E  P VQ+CYHG+GQSY
Sbjct: 338 TNSQVRWEYCKIPSCDSS-----------PV-STEQLAPTAPPELTPVVQDCYHGDGQSY 385

Query: 493 RGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYTRDPGVR 552
           RGT STT TG+ CQ+WSSMTPH H +TPE YPNAGL MNYCRNPDA   P+C+T DP VR
Sbjct: 386 RGTSSTTTTGKKCQSWSSMTPHRHQKTPENYPNAGLTMNYCRNPDADKGPWCFTTDPSVR 445

Query: 553 WEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYST 612
           WEYCNL +CS  E + VAPP V  +P +E PSE          ++C  GNG+ YRG  +T
Sbjct: 446 WEYCNLKKCSGTEASVVAPPPVVLLPDVETPSE----------EDCMFGNGKGYRGKRAT 495

Query: 613 TVTGRTCQAWSSMTPHSHS-RTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYC 670
           TVTG  CQ W++  PH HS  TPE  P AGL  NYCRNPD  V  P+CYT +P   ++YC
Sbjct: 496 TVTGTPCQDWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDVGGPWCYTTNPRKLYDYC 555

Query: 671 NLTQCSDAEGTAVAPPTVTP 690
           ++ QC+ A       P V P
Sbjct: 556 DVPQCA-APSFDCGKPQVEP 574



 Score =  514 bits (1325), Expect = e-145
 Identities = 256/560 (45%), Positives = 324/560 (57%), Gaps = 83/560 (14%)

Query: 248 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 307
           E++  + EC  GNG++YRGT S T  G TCQ WSS +PH    +P  +P+ GL  NYCRN
Sbjct: 95  EKKVYLSECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENYCRN 154

Query: 308 PDA-VAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 366
           PD     P+CYT DP  R++YC++ +C +                               
Sbjct: 155 PDNDPQGPWCYTTDPEKRYDYCDILECEE------------------------------- 183

Query: 367 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 426
             EC H +G++Y G  S T++G  CQAW S +PH+H   P  +PN  L  NYCRNPD   
Sbjct: 184 --ECMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPDREL 241

Query: 427 APYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYH 486
            P+C+T DP  RWE C++ +C+            TP PS        PT Q      C  
Sbjct: 242 RPWCFTTDPNKRWELCDIPRCT------------TPPPS------SGPTYQ------CLK 277

Query: 487 GNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYT 546
           G G++YRG  + TV+G TCQ WS+ TPH+H+RTPE +P   L  NYCRNPD   AP+C+T
Sbjct: 278 GTGENYRGNVAVTVSGHTCQHWSAQTPHTHNRTPENFPCKNLDENYCRNPDGKRAPWCHT 337

Query: 547 RDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSY 606
            +  VRWEYC +  C  +           PV S E  +  AP E  P VQ+CYHG+GQSY
Sbjct: 338 TNSQVRWEYCKIPSCDSS-----------PV-STEQLAPTAPPELTPVVQDCYHGDGQSY 385

Query: 607 RGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYTRDPGVR 666
           RGT STT TG+ CQ+WSSMTPH H +TPE YPNAGL MNYCRNPDA   P+C+T DP VR
Sbjct: 386 RGTSSTTTTGKKCQSWSSMTPHRHQKTPENYPNAGLTMNYCRNPDADKGPWCFTTDPSVR 445

Query: 667 WEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYST 726
           WEYCNL +CS  E + VAPP V  +P +E PSE          ++C  GNG+ YRG  +T
Sbjct: 446 WEYCNLKKCSGTEASVVAPPPVVLLPDVETPSE----------EDCMFGNGKGYRGKRAT 495

Query: 727 TVTGRTCQAWSSMTPHSHS-RTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYC 784
           TVTG  CQ W++  PH HS  TPE  P AGL  NYCRNPD  V  P+CYT +P   ++YC
Sbjct: 496 TVTGTPCQDWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDVGGPWCYTTNPRKLYDYC 555

Query: 785 NLTQCSDAEGTAVAPPTVTP 804
           ++ QC+ A       P V P
Sbjct: 556 DVPQCA-APSFDCGKPQVEP 574



 Score =  514 bits (1324), Expect = e-145
 Identities = 252/546 (46%), Positives = 320/546 (58%), Gaps = 82/546 (15%)

Query: 362 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 421
           E++  + EC  GNG++YRGT S T  G TCQ WSS +PH    +P  +P+ GL  NYCRN
Sbjct: 95  EKKVYLSECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENYCRN 154

Query: 422 PDA-VAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 480
           PD     P+CYT DP  R++YC++ +C +                               
Sbjct: 155 PDNDPQGPWCYTTDPEKRYDYCDILECEE------------------------------- 183

Query: 481 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 540
             EC H +G++Y G  S T++G  CQAW S +PH+H   P  +PN  L  NYCRNPD   
Sbjct: 184 --ECMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPDREL 241

Query: 541 APYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYH 600
            P+C+T DP  RWE C++ +C+            TP PS        PT Q      C  
Sbjct: 242 RPWCFTTDPNKRWELCDIPRCT------------TPPPS------SGPTYQ------CLK 277

Query: 601 GNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYT 660
           G G++YRG  + TV+G TCQ WS+ TPH+H+RTPE +P   L  NYCRNPD   AP+C+T
Sbjct: 278 GTGENYRGNVAVTVSGHTCQHWSAQTPHTHNRTPENFPCKNLDENYCRNPDGKRAPWCHT 337

Query: 661 RDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSY 720
            +  VRWEYC +  C  +           PV S E  +  AP E  P VQ+CYHG+GQSY
Sbjct: 338 TNSQVRWEYCKIPSCDSS-----------PV-STEQLAPTAPPELTPVVQDCYHGDGQSY 385

Query: 721 RGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYTRDPGVR 780
           RGT STT TG+ CQ+WSSMTPH H +TPE YPNAGL MNYCRNPDA   P+C+T DP VR
Sbjct: 386 RGTSSTTTTGKKCQSWSSMTPHRHQKTPENYPNAGLTMNYCRNPDADKGPWCFTTDPSVR 445

Query: 781 WEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYST 840
           WEYCNL +CS  E + VAPP V  +P +E PSE          ++C  GNG+ YRG  +T
Sbjct: 446 WEYCNLKKCSGTEASVVAPPPVVLLPDVETPSE----------EDCMFGNGKGYRGKRAT 495

Query: 841 TVTGRTCQAWSSMTPHSHS-RTPEYYPNAGLIMNYCRNPD-PVAAPYCYTRDPSVRWEYC 898
           TVTG  CQ W++  PH HS  TPE  P AGL  NYCRNPD  V  P+CYT +P   ++YC
Sbjct: 496 TVTGTPCQDWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDVGGPWCYTTNPRKLYDYC 555

Query: 899 NLTQCS 904
           ++ QC+
Sbjct: 556 DVPQCA 561



 Score =  514 bits (1323), Expect = e-145
 Identities = 259/587 (44%), Positives = 331/587 (56%), Gaps = 98/587 (16%)

Query: 476  EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 535
            E++  + EC  GNG++YRGT S T  G TCQ WSS +PH    +P  +P+ GL  NYCRN
Sbjct: 95   EKKVYLSECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENYCRN 154

Query: 536  PDA-VAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 594
            PD     P+CYT DP  R++YC++ +C +                               
Sbjct: 155  PDNDPQGPWCYTTDPEKRYDYCDILECEE------------------------------- 183

Query: 595  VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 654
              EC H +G++Y G  S T++G  CQAW S +PH+H   P  +PN  L  NYCRNPD   
Sbjct: 184  --ECMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPDREL 241

Query: 655  APYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYH 714
             P+C+T DP  RWE C++ +C+            TP PS        PT Q      C  
Sbjct: 242  RPWCFTTDPNKRWELCDIPRCT------------TPPPS------SGPTYQ------CLK 277

Query: 715  GNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYT 774
            G G++YRG  + TV+G TCQ WS+ TPH+H+RTPE +P   L  NYCRNPD   AP+C+T
Sbjct: 278  GTGENYRGNVAVTVSGHTCQHWSAQTPHTHNRTPENFPCKNLDENYCRNPDGKRAPWCHT 337

Query: 775  RDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSY 834
             +  VRWEYC +  C  +           PV S E  +  AP E  P VQ+CYHG+GQSY
Sbjct: 338  TNSQVRWEYCKIPSCDSS-----------PV-STEQLAPTAPPELTPVVQDCYHGDGQSY 385

Query: 835  RGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDPVAAPYCYTRDPSVR 894
            RGT STT TG+ CQ+WSSMTPH H +TPE YPNAGL MNYCRNPD    P+C+T DPSVR
Sbjct: 386  RGTSSTTTTGKKCQSWSSMTPHRHQKTPENYPNAGLTMNYCRNPDADKGPWCFTTDPSVR 445

Query: 895  WEYCNLTQCSDAEGTAVAPPTITPIPSLEAPSEQAPTEQRPGVQECYHGNGQSYQGTYFI 954
            WEYCNL +CS  E + VAPP +  +P +E PSE          ++C  GNG+ Y+G    
Sbjct: 446  WEYCNLKKCSGTEASVVAPPPVVLLPDVETPSE----------EDCMFGNGKGYRGKRAT 495

Query: 955  TVTGRTCQAWSSMTPHSHS-RTPAYYPNAGLIKNYCRNPD-PVAAPWCYTTDPSVRWEYC 1012
            TVTG  CQ W++  PH HS  TP   P AGL KNYCRNPD  V  PWCYTT+P   ++YC
Sbjct: 496  TVTGTPCQDWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDVGGPWCYTTNPRKLYDYC 555

Query: 1013 NLTRCSDAEWTAFVPPNVILAPSLEAFFEQALTEETPG--VQDCYYH 1057
            ++ +C+              APS +    Q   ++ PG  V  C  H
Sbjct: 556  DVPQCA--------------APSFDCGKPQVEPKKCPGRVVGGCVAH 588



 Score =  510 bits (1313), Expect = e-144
 Identities = 253/560 (45%), Positives = 323/560 (57%), Gaps = 83/560 (14%)

Query: 20  EQSHVVQDCYHGDGQSYRGTYSTTVTGRTCQAWSSMTPHQHNRTTENYPNAGLIMNYCRN 79
           E+   + +C  G+G++YRGT S T  G TCQ WSS +PH+   +   +P+ GL  NYCRN
Sbjct: 95  EKKVYLSECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENYCRN 154

Query: 80  PDA-VAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 138
           PD     P+CYT DP  R++YC++ +C +                               
Sbjct: 155 PDNDPQGPWCYTTDPEKRYDYCDILECEE------------------------------- 183

Query: 139 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 198
             EC H +G++Y G  S T++G  CQAW S +PH+H   P  +PN  L  NYCRNPD   
Sbjct: 184 --ECMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPDREL 241

Query: 199 APYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYH 258
            P+C+T DP  RWE C++ +C+            TP PS        PT Q      C  
Sbjct: 242 RPWCFTTDPNKRWELCDIPRCT------------TPPPS------SGPTYQ------CLK 277

Query: 259 GNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYT 318
           G G++YRG  + TV+G TCQ WS+ TPH+H+RTPE +P   L  NYCRNPD   AP+C+T
Sbjct: 278 GTGENYRGNVAVTVSGHTCQHWSAQTPHTHNRTPENFPCKNLDENYCRNPDGKRAPWCHT 337

Query: 319 RDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSY 378
            +  VRWEYC +  C  +           PV S E  +  AP E  P VQ+CYHG+GQSY
Sbjct: 338 TNSQVRWEYCKIPSCDSS-----------PV-STEQLAPTAPPELTPVVQDCYHGDGQSY 385

Query: 379 RGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYTRDPGVR 438
           RGT STT TG+ CQ+WSSMTPH H +TPE YPNAGL MNYCRNPDA   P+C+T DP VR
Sbjct: 386 RGTSSTTTTGKKCQSWSSMTPHRHQKTPENYPNAGLTMNYCRNPDADKGPWCFTTDPSVR 445

Query: 439 WEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQSYRGTYST 498
           WEYCNL +CS  E + VAPP V  +P +E PSE          ++C  GNG+ YRG  +T
Sbjct: 446 WEYCNLKKCSGTEASVVAPPPVVLLPDVETPSE----------EDCMFGNGKGYRGKRAT 495

Query: 499 TVTGRTCQAWSSMTPHSHS-RTPEYYPNAGLIMNYCRNPDA-VAAPYCYTRDPGVRWEYC 556
           TVTG  CQ W++  PH HS  TPE  P AGL  NYCRNPD  V  P+CYT +P   ++YC
Sbjct: 496 TVTGTPCQDWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDVGGPWCYTTNPRKLYDYC 555

Query: 557 NLTQCSDAEGTAVAPPTVTP 576
           ++ QC+ A       P V P
Sbjct: 556 DVPQCA-APSFDCGKPQVEP 574



 Score =  508 bits (1308), Expect = e-143
 Identities = 249/545 (45%), Positives = 317/545 (58%), Gaps = 82/545 (15%)

Query: 704  EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 763
            E++  + EC  GNG++YRGT S T  G TCQ WSS +PH    +P  +P+ GL  NYCRN
Sbjct: 95   EKKVYLSECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENYCRN 154

Query: 764  PDA-VAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 822
            PD     P+CYT DP  R++YC++ +C +                               
Sbjct: 155  PDNDPQGPWCYTTDPEKRYDYCDILECEE------------------------------- 183

Query: 823  VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDPVA 882
              EC H +G++Y G  S T++G  CQAW S +PH+H   P  +PN  L  NYCRNPD   
Sbjct: 184  --ECMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPDREL 241

Query: 883  APYCYTRDPSVRWEYCNLTQCSDAEGTAVAPPTITPIPSLEAPSEQAPTEQRPGVQECYH 942
             P+C+T DP+ RWE C++ +C+            TP PS        PT Q      C  
Sbjct: 242  RPWCFTTDPNKRWELCDIPRCT------------TPPPS------SGPTYQ------CLK 277

Query: 943  GNGQSYQGTYFITVTGRTCQAWSSMTPHSHSRTPAYYPNAGLIKNYCRNPDPVAAPWCYT 1002
            G G++Y+G   +TV+G TCQ WS+ TPH+H+RTP  +P   L +NYCRNPD   APWC+T
Sbjct: 278  GTGENYRGNVAVTVSGHTCQHWSAQTPHTHNRTPENFPCKNLDENYCRNPDGKRAPWCHT 337

Query: 1003 TDPSVRWEYCNLTRCSDAEWTAFVPPNVILAPSLEAFFEQALTEETPGVQDCYYHYGQSY 1062
            T+  VRWEYC +  C  +              S E     A  E TP VQDCY+  GQSY
Sbjct: 338  TNSQVRWEYCKIPSCDSSP------------VSTEQLAPTAPPELTPVVQDCYHGDGQSY 385

Query: 1063 RGTYSTTVTGRTCQAWSSMTPHQHSRTPENYPNAGLTRNYCRNPDAEIRPWCYTMDPSVR 1122
            RGT STT TG+ CQ+WSSMTPH+H +TPENYPNAGLT NYCRNPDA+  PWC+T DPSVR
Sbjct: 386  RGTSSTTTTGKKCQSWSSMTPHRHQKTPENYPNAGLTMNYCRNPDADKGPWCFTTDPSVR 445

Query: 1123 WEYCNLTQCLVTESSVLATLTVVPDPSTEASSEEAPTEQSPGVQDCYHGDGQSYRGSFST 1182
            WEYCNL +C  TE+SV+A   VV  P  E  SEE          DC  G+G+ YRG  +T
Sbjct: 446  WEYCNLKKCSGTEASVVAPPPVVLLPDVETPSEE----------DCMFGNGKGYRGKRAT 495

Query: 1183 TVTGRTCQSWSSMTPHWHQ-RTTEYYPNGGLTRNYCRNPDAEI-SPWCYTMDPNVRWEYC 1240
            TVTG  CQ W++  PH H   T E  P  GL +NYCRNPD ++  PWCYT +P   ++YC
Sbjct: 496  TVTGTPCQDWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDVGGPWCYTTNPRKLYDYC 555

Query: 1241 NLTQC 1245
            ++ QC
Sbjct: 556  DVPQC 560



 Score =  357 bits (917), Expect = 5e-98
 Identities = 172/332 (51%), Positives = 208/332 (62%), Gaps = 25/332 (7%)

Query: 19  PEQSHVVQDCYHGDGQSYRGTYSTTVTGRTCQAWSSMTPHQHNRTTENYPNAGLIMNYCR 78
           P  S     C  G G++YRG  + TV+G TCQ WS+ TPH HNRT EN+P   L  NYCR
Sbjct: 266 PPSSGPTYQCLKGTGENYRGNVAVTVSGHTCQHWSAQTPHTHNRTPENFPCKNLDENYCR 325

Query: 79  NPDAVAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 138
           NPD   AP+C+T +  VRWEYC +  C  +           PV S E  +  AP E  P 
Sbjct: 326 NPDGKRAPWCHTTNSQVRWEYCKIPSCDSS-----------PV-STEQLAPTAPPELTPV 373

Query: 139 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 198
           VQ+CYHG+GQSYRGT STT TG+ CQ+WSSMTPH H +TPE YPNAGL MNYCRNPDA  
Sbjct: 374 VQDCYHGDGQSYRGTSSTTTTGKKCQSWSSMTPHRHQKTPENYPNAGLTMNYCRNPDADK 433

Query: 199 APYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYH 258
            P+C+T DP VRWEYCNL +CS  E + VAPP V  +P +E PSE          ++C  
Sbjct: 434 GPWCFTTDPSVRWEYCNLKKCSGTEASVVAPPPVVLLPDVETPSE----------EDCMF 483

Query: 259 GNGQSYRGTYSTTVTGRTCQAWSSMTPHSHS-RTPEYYPNAGLIMNYCRNPDA-VAAPYC 316
           GNG+ YRG  +TTVTG  CQ W++  PH HS  TPE  P AGL  NYCRNPD  V  P+C
Sbjct: 484 GNGKGYRGKRATTVTGTPCQDWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDVGGPWC 543

Query: 317 YTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTP 348
           YT +P   ++YC++ QC+ A       P V P
Sbjct: 544 YTTNPRKLYDYCDVPQCA-APSFDCGKPQVEP 574



 Score =  265 bits (677), Expect = 3e-70
 Identities = 125/221 (56%), Positives = 150/221 (67%), Gaps = 13/221 (5%)

Query: 16  SAAPEQSHVVQDCYHGDGQSYRGTYSTTVTGRTCQAWSSMTPHQHNRTTENYPNAGLIMN 75
           +A PE + VVQDCYHGDGQSYRGT STT TG+ CQ+WSSMTPH+H +T ENYPNAGL MN
Sbjct: 365 TAPPELTPVVQDCYHGDGQSYRGTSSTTTTGKKCQSWSSMTPHRHQKTPENYPNAGLTMN 424

Query: 76  YCRNPDAVAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQ 135
           YCRNPDA   P+C+T DP VRWEYCNL +CS  E + VAPP V  +P +E PSE      
Sbjct: 425 YCRNPDADKGPWCFTTDPSVRWEYCNLKKCSGTEASVVAPPPVVLLPDVETPSE------ 478

Query: 136 RPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHS-RTPEYYPNAGLIMNYCRNP 194
               ++C  GNG+ YRG  +TTVTG  CQ W++  PH HS  TPE  P AGL  NYCRNP
Sbjct: 479 ----EDCMFGNGKGYRGKRATTVTGTPCQDWAAQEPHRHSIFTPETNPRAGLEKNYCRNP 534

Query: 195 DA-VAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTP 234
           D  V  P+CYT +P   ++YC++ QC+ A       P V P
Sbjct: 535 DGDVGGPWCYTTNPRKLYDYCDVPQCA-APSFDCGKPQVEP 574



 Score = 34.3 bits (77), Expect = 1.3
 Identities = 17/20 (85%), Positives = 17/20 (85%)

Query: 1  MEHKEVVLLLLLFLKSAAPE 20
          MEHKEVVLLLLLFLKS   E
Sbjct: 1  MEHKEVVLLLLLFLKSGQGE 20


>gi|205277383 macrophage stimulating 1 (hepatocyte growth factor-like)
            [Homo sapiens]
          Length = 725

 Score =  465 bits (1196), Expect = e-130
 Identities = 257/681 (37%), Positives = 347/681 (50%), Gaps = 105/681 (15%)

Query: 1385 VQDCYRGDGQSYRGTLSTTITGRTCQSWSSMTPHWHRRIPLYYPNAGLTRNYCRNPDAEI 1444
            V+ C   +G  YRGT++TT+ G  CQ+WS   P+ H+  P      GL  N+CRNPD + 
Sbjct: 121  VRTCIMNNGVGYRGTMATTVGGLPCQAWSHKFPNDHKYTPTL--RNGLEENFCRNPDGDP 178

Query: 1445 R-PWCYTMDPSVRWEYCNLTRCPVTESSVLTTPTVAPVPSTEAPSEQAPPEKSPVVQDCY 1503
              PWCYT DP+VR++ C +  C                       E A          C 
Sbjct: 179  GGPWCYTTDPAVRFQSCGIKSC----------------------REAA----------CV 206

Query: 1504 HGDGRSYRGISSTTVTGRTCQSWSSMIPHWHQRTPENYPNAGLTENYCRNPDSGKQPWCY 1563
              +G  YRG    T +GR CQ W    PH H   P  + + GL +NYCRNPD  ++PWCY
Sbjct: 207  WCNGEEYRGAVDRTESGRECQRWDLQHPHQHPFEPGKFLDQGLDDNYCRNPDGSERPWCY 266

Query: 1564 TTDPCVRWEYCNLTQCSETESGVLETPTVVPVPSMEAHSEAAPTEQTPVVRQCYHGNGQS 1623
            TTDP +  E+C+L +C                      SEA P ++   V  C+ G G+ 
Sbjct: 267  TTDPQIEREFCDLPRCG---------------------SEAQPRQEATTV-SCFRGKGEG 304

Query: 1624 YRGTFSTTVTGRTCQSWSSMTPHRHQRTPENYPNDGLTMNYCRNPDADTGPWCFTMDPSI 1683
            YRGT +TT  G  CQ W +  PH+H+ TPE Y    L  N+CRNPD    PWCFT+ P +
Sbjct: 305  YRGTANTTTAGVPCQRWDAQIPHQHRFTPEKYACKDLRENFCRNPDGSEAPWCFTLRPGM 364

Query: 1684 RWEYC-NLTRCSDTEGTVVAPPTVIQVPSLGPPSEQDCMFGNGKGYRGKKATTVTGTPCQ 1742
            R  +C  + RC+D     V P              QDC  G G+ YRG  + T  G  CQ
Sbjct: 365  RAAFCYQIRRCTDD----VRP--------------QDCYHGAGEQYRGTVSKTRKGVQCQ 406

Query: 1743 EWAAQEPHRHSTFIPGTNKWAGLEKNYCRNPDGDINGPWCYTMNPRKLFDYCDIPLCAS- 1801
             W+A+ PH+   F   +   A LE+N+CRNPDGD +GPWCYTM+PR  FDYC +  CA  
Sbjct: 407  RWSAETPHK-PQFTFTSEPHAQLEENFCRNPDGDSHGPWCYTMDPRTPFDYCALRRCADD 465

Query: 1802 ---SSFD---------CGK--PQVEPKKCPGSIVGGCVAHPHSWPWQVSLRTRFGKHFCG 1847
               S  D         CGK   +++ ++    +VGG   HP + PW VSLR R G+HFCG
Sbjct: 466  QPPSILDPPDQVQFEKCGKRVDRLDQRRSKLRVVGG---HPGNSPWTVSLRNRQGQHFCG 522

Query: 1848 GTLISPEWVLTAAHCLKKSSRP-SSYKVILGA--HQEVNLESHVQEIEVSRLFLEPTQAD 1904
            G+L+  +W+LTA  C      P + Y+V LG       + E  +Q + V+++   P+ + 
Sbjct: 523  GSLVKEQWILTARQCFSSCHMPLTGYEVWLGTLFQNPQHGEPSLQRVPVAKMVCGPSGSQ 582

Query: 1905 IALLKLSRPAVITDKVMPACLPSPDYMVTARTECYITGWGETQGTFGTGLLKEAQLLVIE 1964
            + LLKL R   +  +V   CLP   Y+V   T+C I GWGET+GT    +L  A L VI 
Sbjct: 583  LVLLKLERSVTLNQRVALICLPPEWYVVPPGTKCEIAGWGETKGTGNDTVLNVALLNVIS 642

Query: 1965 NEVCN-------HYKYICAEHLARGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARP 2017
            N+ CN           +C E L     +C+GD GGPL CF  + ++L+G+      CAR 
Sbjct: 643  NQECNIKHRGRVRESEMCTEGLLAPVGACEGDYGGPLACFTHNCWVLEGIIIPNRVCARS 702

Query: 2018 NKPGVYARVSRFVTWIEGMMR 2038
              P V+ RVS FV WI  +MR
Sbjct: 703  RWPAVFTRVSVFVDWIHKVMR 723



 Score =  302 bits (773), Expect = 3e-81
 Identities = 157/423 (37%), Positives = 206/423 (48%), Gaps = 79/423 (18%)

Query: 932  EQRPGVQECYHGNGQSYQGTYFITVTGRTCQAWSSMTPHSHSRTPAYYPNAGLIKNYCRN 991
            +++  V+ C   NG  Y+GT   TV G  CQAWS   P+ H  TP      GL +N+CRN
Sbjct: 116  QKKDYVRTCIMNNGVGYRGTMATTVGGLPCQAWSHKFPNDHKYTPTL--RNGLEENFCRN 173

Query: 992  PD-PVAAPWCYTTDPSVRWEYCNLTRCSDAEWTAFVPPNVILAPSLEAFFEQALTEETPG 1050
            PD     PWCYTTDP+VR++ C +  C +A                              
Sbjct: 174  PDGDPGGPWCYTTDPAVRFQSCGIKSCREAA----------------------------- 204

Query: 1051 VQDCYYHYGQSYRGTYSTTVTGRTCQAWSSMTPHQHSRTPENYPNAGLTRNYCRNPDAEI 1110
               C +  G+ YRG    T +GR CQ W    PHQH   P  + + GL  NYCRNPD   
Sbjct: 205  ---CVWCNGEEYRGAVDRTESGRECQRWDLQHPHQHPFEPGKFLDQGLDDNYCRNPDGSE 261

Query: 1111 RPWCYTMDPSVRWEYCNLTQCLVTESSVLATLTVVPDPSTEASSEEAPTEQSPGVQDCYH 1170
            RPWCYT DP +  E+C+L +C                      SE  P +++  V  C+ 
Sbjct: 262  RPWCYTTDPQIEREFCDLPRC---------------------GSEAQPRQEATTV-SCFR 299

Query: 1171 GDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRNPDAEISPWCYT 1230
            G G+ YRG+ +TT  G  CQ W +  PH H+ T E Y    L  N+CRNPD   +PWC+T
Sbjct: 300  GKGEGYRGTANTTTAGVPCQRWDAQIPHQHRFTPEKYACKDLRENFCRNPDGSEAPWCFT 359

Query: 1231 MDPNVRWEYC-NLTQCPVTESSVLATSTAVSEQAPTEQSPTVQDCYHGDGQSYRGSFSTT 1289
            + P +R  +C  + +C               +  P       QDCYHG G+ YRG+ S T
Sbjct: 360  LRPGMRAAFCYQIRRC-------------TDDVRP-------QDCYHGAGEQYRGTVSKT 399

Query: 1290 VTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRNPDAEIR-PWCYTMDPSVRWEYCNL 1348
              G  CQ WS+ TPH  Q T    P+  L  N+CRNPD +   PWCYTMDP   ++YC L
Sbjct: 400  RKGVQCQRWSAETPHKPQFTFTSEPHAQLEENFCRNPDGDSHGPWCYTMDPRTPFDYCAL 459

Query: 1349 TQC 1351
             +C
Sbjct: 460  RRC 462



 Score =  293 bits (749), Expect = 2e-78
 Identities = 162/433 (37%), Positives = 208/433 (48%), Gaps = 80/433 (18%)

Query: 1165 VQDCYHGDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRNPDAEI 1224
            V+ C   +G  YRG+ +TTV G  CQ+WS   P+ H+ T       GL  N+CRNPD + 
Sbjct: 121  VRTCIMNNGVGYRGTMATTVGGLPCQAWSHKFPNDHKYTPTL--RNGLEENFCRNPDGDP 178

Query: 1225 S-PWCYTMDPNVRWEYCNLTQCPVTESSVLATSTAVSEQAPTEQSPTVQDCYHGDGQSYR 1283
              PWCYT DP VR++ C +  C               E A          C   +G+ YR
Sbjct: 179  GGPWCYTTDPAVRFQSCGIKSC--------------REAA----------CVWCNGEEYR 214

Query: 1284 GSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRNPDAEIRPWCYTMDPSVRW 1343
            G+   T +GR CQ W    PH H      + + GL  NYCRNPD   RPWCYT DP +  
Sbjct: 215  GAVDRTESGRECQRWDLQHPHQHPFEPGKFLDQGLDDNYCRNPDGSERPWCYTTDPQIER 274

Query: 1344 EYCNLTQCPVMESTLLTTPTVVPVPSTELPSEEAPTENSTGVQDCYRGDGQSYRGTLSTT 1403
            E+C+L +C                      SE  P + +T V  C+RG G+ YRGT +TT
Sbjct: 275  EFCDLPRC---------------------GSEAQPRQEATTV-SCFRGKGEGYRGTANTT 312

Query: 1404 ITGRTCQSWSSMTPHWHRRIPLYYPNAGLTRNYCRNPDAEIRPWCYTMDPSVRWEYC-NL 1462
              G  CQ W +  PH HR  P  Y    L  N+CRNPD    PWC+T+ P +R  +C  +
Sbjct: 313  TAGVPCQRWDAQIPHQHRFTPEKYACKDLRENFCRNPDGSEAPWCFTLRPGMRAAFCYQI 372

Query: 1463 TRCPVTESSVLTTPTVAPVPSTEAPSEQAPPEKSPVVQDCYHGDGRSYRGISSTTVTGRT 1522
             RC         T  V P                   QDCYHG G  YRG  S T  G  
Sbjct: 373  RRC---------TDDVRP-------------------QDCYHGAGEQYRGTVSKTRKGVQ 404

Query: 1523 CQSWSSMIPHWHQRTPENYPNAGLTENYCRNPDSGKQ-PWCYTTDPCVRWEYCNLTQCSE 1581
            CQ WS+  PH  Q T  + P+A L EN+CRNPD     PWCYT DP   ++YC L +C++
Sbjct: 405  CQRWSAETPHKPQFTFTSEPHAQLEENFCRNPDGDSHGPWCYTMDPRTPFDYCALRRCAD 464

Query: 1582 TE-SGVLETPTVV 1593
             +   +L+ P  V
Sbjct: 465  DQPPSILDPPDQV 477



 Score =  291 bits (745), Expect = 4e-78
 Identities = 160/442 (36%), Positives = 210/442 (47%), Gaps = 87/442 (19%)

Query: 134 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 193
           +++  V+ C   NG  YRGT +TTV G  CQAWS   P+ H  TP      GL  N+CRN
Sbjct: 116 QKKDYVRTCIMNNGVGYRGTMATTVGGLPCQAWSHKFPNDHKYTPTL--RNGLEENFCRN 173

Query: 194 PDA-VAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 252
           PD     P+CYT DP VR++ C +  C +A                              
Sbjct: 174 PDGDPGGPWCYTTDPAVRFQSCGIKSCREAA----------------------------- 204

Query: 253 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 312
              C   NG+ YRG    T +GR CQ W    PH H   P  + + GL  NYCRNPD   
Sbjct: 205 ---CVWCNGEEYRGAVDRTESGRECQRWDLQHPHQHPFEPGKFLDQGLDDNYCRNPDGSE 261

Query: 313 APYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYH 372
            P+CYT DP +  E+C+L +C                      SE  P ++   V  C+ 
Sbjct: 262 RPWCYTTDPQIEREFCDLPRCG---------------------SEAQPRQEATTVS-CFR 299

Query: 373 GNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYT 432
           G G+ YRGT +TT  G  CQ W +  PH H  TPE Y    L  N+CRNPD   AP+C+T
Sbjct: 300 GKGEGYRGTANTTTAGVPCQRWDAQIPHQHRFTPEKYACKDLRENFCRNPDGSEAPWCFT 359

Query: 433 RDPGVRWEYC-NLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQS 491
             PG+R  +C  + +C+D                          + RP  Q+CYHG G+ 
Sbjct: 360 LRPGMRAAFCYQIRRCTD--------------------------DVRP--QDCYHGAGEQ 391

Query: 492 YRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA-APYCYTRDPG 550
           YRGT S T  G  CQ WS+ TPH    T    P+A L  N+CRNPD  +  P+CYT DP 
Sbjct: 392 YRGTVSKTRKGVQCQRWSAETPHKPQFTFTSEPHAQLEENFCRNPDGDSHGPWCYTMDPR 451

Query: 551 VRWEYCNLTQCSDAEGTAVAPP 572
             ++YC L +C+D +  ++  P
Sbjct: 452 TPFDYCALRRCADDQPPSILDP 473



 Score =  291 bits (745), Expect = 4e-78
 Identities = 160/442 (36%), Positives = 210/442 (47%), Gaps = 87/442 (19%)

Query: 362 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 421
           +++  V+ C   NG  YRGT +TTV G  CQAWS   P+ H  TP      GL  N+CRN
Sbjct: 116 QKKDYVRTCIMNNGVGYRGTMATTVGGLPCQAWSHKFPNDHKYTPTL--RNGLEENFCRN 173

Query: 422 PDA-VAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 480
           PD     P+CYT DP VR++ C +  C +A                              
Sbjct: 174 PDGDPGGPWCYTTDPAVRFQSCGIKSCREAA----------------------------- 204

Query: 481 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 540
              C   NG+ YRG    T +GR CQ W    PH H   P  + + GL  NYCRNPD   
Sbjct: 205 ---CVWCNGEEYRGAVDRTESGRECQRWDLQHPHQHPFEPGKFLDQGLDDNYCRNPDGSE 261

Query: 541 APYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYH 600
            P+CYT DP +  E+C+L +C                      SE  P ++   V  C+ 
Sbjct: 262 RPWCYTTDPQIEREFCDLPRCG---------------------SEAQPRQEATTVS-CFR 299

Query: 601 GNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYT 660
           G G+ YRGT +TT  G  CQ W +  PH H  TPE Y    L  N+CRNPD   AP+C+T
Sbjct: 300 GKGEGYRGTANTTTAGVPCQRWDAQIPHQHRFTPEKYACKDLRENFCRNPDGSEAPWCFT 359

Query: 661 RDPGVRWEYC-NLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQS 719
             PG+R  +C  + +C+D                          + RP  Q+CYHG G+ 
Sbjct: 360 LRPGMRAAFCYQIRRCTD--------------------------DVRP--QDCYHGAGEQ 391

Query: 720 YRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA-APYCYTRDPG 778
           YRGT S T  G  CQ WS+ TPH    T    P+A L  N+CRNPD  +  P+CYT DP 
Sbjct: 392 YRGTVSKTRKGVQCQRWSAETPHKPQFTFTSEPHAQLEENFCRNPDGDSHGPWCYTMDPR 451

Query: 779 VRWEYCNLTQCSDAEGTAVAPP 800
             ++YC L +C+D +  ++  P
Sbjct: 452 TPFDYCALRRCADDQPPSILDP 473



 Score =  290 bits (742), Expect = 1e-77
 Identities = 162/453 (35%), Positives = 213/453 (47%), Gaps = 92/453 (20%)

Query: 590  EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 649
            +++  V+ C   NG  YRGT +TTV G  CQAWS   P+ H  TP      GL  N+CRN
Sbjct: 116  QKKDYVRTCIMNNGVGYRGTMATTVGGLPCQAWSHKFPNDHKYTPTL--RNGLEENFCRN 173

Query: 650  PDA-VAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 708
            PD     P+CYT DP VR++ C +  C +A                              
Sbjct: 174  PDGDPGGPWCYTTDPAVRFQSCGIKSCREAA----------------------------- 204

Query: 709  VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 768
               C   NG+ YRG    T +GR CQ W    PH H   P  + + GL  NYCRNPD   
Sbjct: 205  ---CVWCNGEEYRGAVDRTESGRECQRWDLQHPHQHPFEPGKFLDQGLDDNYCRNPDGSE 261

Query: 769  APYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYH 828
             P+CYT DP +  E+C+L +C                      SE  P ++   V  C+ 
Sbjct: 262  RPWCYTTDPQIEREFCDLPRCG---------------------SEAQPRQEATTVS-CFR 299

Query: 829  GNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDPVAAPYCYT 888
            G G+ YRGT +TT  G  CQ W +  PH H  TPE Y    L  N+CRNPD   AP+C+T
Sbjct: 300  GKGEGYRGTANTTTAGVPCQRWDAQIPHQHRFTPEKYACKDLRENFCRNPDGSEAPWCFT 359

Query: 889  RDPSVRWEYC-NLTQCSDAEGTAVAPPTITPIPSLEAPSEQAPTEQRPGVQECYHGNGQS 947
              P +R  +C  + +C+D                          + RP  Q+CYHG G+ 
Sbjct: 360  LRPGMRAAFCYQIRRCTD--------------------------DVRP--QDCYHGAGEQ 391

Query: 948  YQGTYFITVTGRTCQAWSSMTPHSHSRTPAYYPNAGLIKNYCRNPDPVA-APWCYTTDPS 1006
            Y+GT   T  G  CQ WS+ TPH    T    P+A L +N+CRNPD  +  PWCYT DP 
Sbjct: 392  YRGTVSKTRKGVQCQRWSAETPHKPQFTFTSEPHAQLEENFCRNPDGDSHGPWCYTMDPR 451

Query: 1007 VRWEYCNLTRCSDAEWTAFVPPNVILAPSLEAF 1039
              ++YC L RC+D +     PP+++  P    F
Sbjct: 452  TPFDYCALRRCADDQ-----PPSILDPPDQVQF 479



 Score =  285 bits (730), Expect = 2e-76
 Identities = 158/442 (35%), Positives = 208/442 (47%), Gaps = 87/442 (19%)

Query: 20  EQSHVVQDCYHGDGQSYRGTYSTTVTGRTCQAWSSMTPHQHNRTTENYPNAGLIMNYCRN 79
           ++   V+ C   +G  YRGT +TTV G  CQAWS   P+ H  T       GL  N+CRN
Sbjct: 116 QKKDYVRTCIMNNGVGYRGTMATTVGGLPCQAWSHKFPNDHKYTPT--LRNGLEENFCRN 173

Query: 80  PDA-VAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 138
           PD     P+CYT DP VR++ C +  C +A                              
Sbjct: 174 PDGDPGGPWCYTTDPAVRFQSCGIKSCREA------------------------------ 203

Query: 139 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 198
              C   NG+ YRG    T +GR CQ W    PH H   P  + + GL  NYCRNPD   
Sbjct: 204 --ACVWCNGEEYRGAVDRTESGRECQRWDLQHPHQHPFEPGKFLDQGLDDNYCRNPDGSE 261

Query: 199 APYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYH 258
            P+CYT DP +  E+C+L +C                      SE  P ++   V  C+ 
Sbjct: 262 RPWCYTTDPQIEREFCDLPRCG---------------------SEAQPRQEATTV-SCFR 299

Query: 259 GNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYT 318
           G G+ YRGT +TT  G  CQ W +  PH H  TPE Y    L  N+CRNPD   AP+C+T
Sbjct: 300 GKGEGYRGTANTTTAGVPCQRWDAQIPHQHRFTPEKYACKDLRENFCRNPDGSEAPWCFT 359

Query: 319 RDPGVRWEYC-NLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQS 377
             PG+R  +C  + +C+D                          + RP  Q+CYHG G+ 
Sbjct: 360 LRPGMRAAFCYQIRRCTD--------------------------DVRP--QDCYHGAGEQ 391

Query: 378 YRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA-APYCYTRDPG 436
           YRGT S T  G  CQ WS+ TPH    T    P+A L  N+CRNPD  +  P+CYT DP 
Sbjct: 392 YRGTVSKTRKGVQCQRWSAETPHKPQFTFTSEPHAQLEENFCRNPDGDSHGPWCYTMDPR 451

Query: 437 VRWEYCNLTQCSDAEGTAVAPP 458
             ++YC L +C+D +  ++  P
Sbjct: 452 TPFDYCALRRCADDQPPSILDP 473



 Score =  219 bits (558), Expect = 2e-56
 Identities = 115/302 (38%), Positives = 141/302 (46%), Gaps = 49/302 (16%)

Query: 1494 EKSPVVQDCYHGDGRSYRGISSTTVTGRTCQSWSSMIPHWHQRTPENYPNAGLTENYCRN 1553
            +K   V+ C   +G  YRG  +TTV G  CQ+WS   P+ H+ TP      GL EN+CRN
Sbjct: 116  QKKDYVRTCIMNNGVGYRGTMATTVGGLPCQAWSHKFPNDHKYTPT--LRNGLEENFCRN 173

Query: 1554 PDSGK-QPWCYTTDPCVRWEYCNLTQCSETESGVLETPTVVPVPSMEAHSEAAPTEQTPV 1612
            PD     PWCYTTDP VR++ C +  C E                               
Sbjct: 174  PDGDPGGPWCYTTDPAVRFQSCGIKSCREA------------------------------ 203

Query: 1613 VRQCYHGNGQSYRGTFSTTVTGRTCQSWSSMTPHRHQRTPENYPNDGLTMNYCRNPDADT 1672
               C   NG+ YRG    T +GR CQ W    PH+H   P  + + GL  NYCRNPD   
Sbjct: 204  --ACVWCNGEEYRGAVDRTESGRECQRWDLQHPHQHPFEPGKFLDQGLDDNYCRNPDGSE 261

Query: 1673 GPWCFTMDPSIRWEYCNLTRCSDTEGTVVAPPTVIQVPSLGPPSEQDCMFGNGKGYRGKK 1732
             PWC+T DP I  E+C+L RC           TV             C  G G+GYRG  
Sbjct: 262  RPWCYTTDPQIEREFCDLPRCGSEAQPRQEATTV------------SCFRGKGEGYRGTA 309

Query: 1733 ATTVTGTPCQEWAAQEPHRHSTFIPGTNKWAGLEKNYCRNPDGDINGPWCYTMNPRKLFD 1792
             TT  G PCQ W AQ PH+H  F P       L +N+CRNPDG    PWC+T+ P     
Sbjct: 310  NTTTAGVPCQRWDAQIPHQH-RFTPEKYACKDLRENFCRNPDGS-EAPWCFTLRPGMRAA 367

Query: 1793 YC 1794
            +C
Sbjct: 368  FC 369



 Score =  164 bits (415), Expect = 8e-40
 Identities = 84/216 (38%), Positives = 111/216 (51%), Gaps = 30/216 (13%)

Query: 17  AAPEQSHVVQDCYHGDGQSYRGTYSTTVTGRTCQAWSSMTPHQHNRTTENYPNAGLIMNY 76
           A P Q      C+ G G+ YRGT +TT  G  CQ W +  PHQH  T E Y    L  N+
Sbjct: 286 AQPRQEATTVSCFRGKGEGYRGTANTTTAGVPCQRWDAQIPHQHRFTPEKYACKDLRENF 345

Query: 77  CRNPDAVAAPYCYTRDPGVRWEYC-NLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQ 135
           CRNPD   AP+C+T  PG+R  +C  + +C+D                          + 
Sbjct: 346 CRNPDGSEAPWCFTLRPGMRAAFCYQIRRCTD--------------------------DV 379

Query: 136 RPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPD 195
           RP  Q+CYHG G+ YRGT S T  G  CQ WS+ TPH    T    P+A L  N+CRNPD
Sbjct: 380 RP--QDCYHGAGEQYRGTVSKTRKGVQCQRWSAETPHKPQFTFTSEPHAQLEENFCRNPD 437

Query: 196 AVA-APYCYTRDPGVRWEYCNLTQCSDAEGTAVAPP 230
             +  P+CYT DP   ++YC L +C+D +  ++  P
Sbjct: 438 GDSHGPWCYTMDPRTPFDYCALRRCADDQPPSILDP 473


>gi|33859835 hepatocyte growth factor isoform 1 preproprotein [Homo
            sapiens]
          Length = 728

 Score =  449 bits (1154), Expect = e-125
 Identities = 252/672 (37%), Positives = 328/672 (48%), Gaps = 93/672 (13%)

Query: 1380 ENSTGVQDCYRGDGQSYRGTLSTTITGRTCQSWSSMTPHWHRRIPLYYPNAGLTRNYCRN 1439
            EN   +++C  G G+SY+GT+S T +G  CQ WSSM PH H  +P  Y    L  NYCRN
Sbjct: 120  ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRN 179

Query: 1440 PDAEIR-PWCYTMDPSVRWEYCNLTRCPVTESSVLTTPTVAPVPSTEAPSEQAPPEKSPV 1498
            P  E   PWC+T +P VR+E C++ +C   E                             
Sbjct: 180  PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 210

Query: 1499 VQDCYHGDGRSYRGISSTTVTGRTCQSWSSMIPHWHQRTPENYPNAGLTENYCRNPDSGK 1558
               C   +G SYRG+   T +G+ CQ W    PH H+  PE YP+ G  +NYCRNPD   
Sbjct: 211  ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 267

Query: 1559 QPWCYTTDPCVRWEYCNLTQCSETESGVLETPTVVPVPSMEAHSEAAPTEQTPVVRQCYH 1618
            +PWCYT DP  RWEYC +  C++         T VP+ + E                C  
Sbjct: 268  RPWCYTLDPHTRWEYCAIKTCADNTM----NDTDVPLETTE----------------CIQ 307

Query: 1619 GNGQSYRGTFSTTVTGRTCQSWSSMTPHRHQRTPENYPNDGLTMNYCRNPDADTGPWCFT 1678
            G G+ YRGT +T   G  CQ W S  PH H  TPEN+    L  NYCRNPD    PWCFT
Sbjct: 308  GQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGSESPWCFT 367

Query: 1679 MDPSIRWEYCNLTRCSDTEGTVVAPPTVIQVPSLGPPSEQDCMFGNGKGYRGKKATTVTG 1738
             DP+IR  YC+                  Q+P+      QDC  GNGK Y G  + T +G
Sbjct: 368  TDPNIRVGYCS------------------QIPNCDMSHGQDCYRGNGKNYMGNLSQTRSG 409

Query: 1739 TPCQEW--AAQEPHRHSTFIPGTNKWAGLEKNYCRNPDGDINGPWCYTMNPRKLFDYCDI 1796
              C  W    ++ HRH  + P  +K   L +NYCRNPD D +GPWCYT NP   +DYC I
Sbjct: 410  LTCSMWDKNMEDLHRHIFWEPDASK---LNENYCRNPDDDAHGPWCYTGNPLIPWDYCPI 466

Query: 1797 PLCASSS----FDCGKPQVEPKKCPGSIVGGCVAHPHSWPWQVSLRTRFGKHFCGGTLIS 1852
              C   +     +   P +   K     V   +    +  W VSLR R  KH CGG+LI 
Sbjct: 467  SRCEGDTTPTIVNLDHPVISCAKTKQLRVVNGIPTRTNIGWMVSLRYR-NKHICGGSLIK 525

Query: 1853 PEWVLTAAHCLKKSSRPSSYKVILGAHQEVNL--ESHVQEIEVSRLFLEPTQADIALLKL 1910
              WVLTA  C   S     Y+  LG H       E   Q + VS+L   P  +D+ L+KL
Sbjct: 526  ESWVLTARQCF-PSRDLKDYEAWLGIHDVHGRGDEKCKQVLNVSQLVYGPEGSDLVLMKL 584

Query: 1911 SRPAVITDKVMPACLPSPDYMVTARTECYITGWGETQGTFGTGLLKEAQLLVIENEVCNH 1970
            +RPAV+ D V    LP+    +  +T C + GWG T      GLL+ A L ++ NE C+ 
Sbjct: 585  ARPAVLDDFVSTIDLPNYGCTIPEKTSCSVYGWGYTGLINYDGLLRVAHLYIMGNEKCSQ 644

Query: 1971 Y---------KYICAEHLARGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPG 2021
            +           ICA     G+  C+GD GGPLVC +    ++ GV   G GCA PN+PG
Sbjct: 645  HHRGKVTLNESEICAGAEKIGSGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPG 704

Query: 2022 VYARVSRFVTWI 2033
            ++ RV+ +  WI
Sbjct: 705  IFVRVAYYAKWI 716



 Score =  318 bits (814), Expect = 4e-86
 Identities = 161/436 (36%), Positives = 210/436 (48%), Gaps = 79/436 (18%)

Query: 932  EQRPGVQECYHGNGQSYQGTYFITVTGRTCQAWSSMTPHSHSRTPAYYPNAGLIKNYCRN 991
            E +  ++ C  G G+SY+GT  IT +G  CQ WSSM PH HS  P+ Y    L +NYCRN
Sbjct: 120  ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRN 179

Query: 992  P-DPVAAPWCYTTDPSVRWEYCNLTRCSDAEWTAFVPPNVILAPSLEAFFEQALTEETPG 1050
            P      PWC+T++P VR+E C++ +CS+ E                             
Sbjct: 180  PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 210

Query: 1051 VQDCYYHYGQSYRGTYSTTVTGRTCQAWSSMTPHQHSRTPENYPNAGLTRNYCRNPDAEI 1110
               C    G+SYRG    T +G+ CQ W   TPH+H   PE YP+ G   NYCRNPD + 
Sbjct: 211  ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 267

Query: 1111 RPWCYTMDPSVRWEYCNLTQCLVTESSVLATLTVVPDPSTEASSEEAPTEQSPGVQDCYH 1170
            RPWCYT+DP  RWEYC +  C                     +  + P E +    +C  
Sbjct: 268  RPWCYTLDPHTRWEYCAIKTC----------------ADNTMNDTDVPLETT----ECIQ 307

Query: 1171 GDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRNPDAEISPWCYT 1230
            G G+ YRG+ +T   G  CQ W S  PH H  T E +    L  NYCRNPD   SPWC+T
Sbjct: 308  GQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGSESPWCFT 367

Query: 1231 MDPNVRWEYCNLTQCPVTESSVLATSTAVSEQAPTEQSPTVQDCYHGDGQSYRGSFSTTV 1290
             DPN+R  YC+                    Q P       QDCY G+G++Y G+ S T 
Sbjct: 368  TDPNIRVGYCS--------------------QIPNCDMSHGQDCYRGNGKNYMGNLSQTR 407

Query: 1291 TGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRNPDAEIR-PWCYTMDPSVRWEYCNLT 1349
            +G TC  W       H+          L  NYCRNPD +   PWCYT +P + W+YC ++
Sbjct: 408  SGLTCSMWDKNMEDLHRHIFWEPDASKLNENYCRNPDDDAHGPWCYTGNPLIPWDYCPIS 467

Query: 1350 QCPVMESTLLTTPTVV 1365
            +C        TTPT+V
Sbjct: 468  RCEGD-----TTPTIV 478



 Score =  316 bits (809), Expect = 2e-85
 Identities = 165/438 (37%), Positives = 215/438 (49%), Gaps = 81/438 (18%)

Query: 1044 LTEETPGVQDCYYHYGQSYRGTYSTTVTGRTCQAWSSMTPHQHSRTPENYPNAGLTRNYC 1103
            L E    +++C    G+SY+GT S T +G  CQ WSSM PH+HS  P +Y    L  NYC
Sbjct: 118  LYENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYC 177

Query: 1104 RNPDAEI-RPWCYTMDPSVRWEYCNLTQCLVTESSVLATLTVVPDPSTEASSEEAPTEQS 1162
            RNP  E   PWC+T +P VR+E C++ QC   E                           
Sbjct: 178  RNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE--------------------------- 210

Query: 1163 PGVQDCYHGDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRNPDA 1222
                 C   +G+SYRG    T +G+ CQ W   TPH H+   E YP+ G   NYCRNPD 
Sbjct: 211  -----CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDG 265

Query: 1223 EISPWCYTMDPNVRWEYCNLTQCPVTESSVLATSTAVSEQAPTEQSPTVQDCYHGDGQSY 1282
            +  PWCYT+DP+ RWEYC +  C        A +T      P E +    +C  G G+ Y
Sbjct: 266  QPRPWCYTLDPHTRWEYCAIKTC--------ADNTMNDTDVPLETT----ECIQGQGEGY 313

Query: 1283 RGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRNPDAEIRPWCYTMDPSVR 1342
            RG+ +T   G  CQ W S  PH H  T E +    L  NYCRNPD    PWC+T DP++R
Sbjct: 314  RGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGSESPWCFTTDPNIR 373

Query: 1343 WEYCNLTQCPVMESTLLTTPTVVPVPSTELPSEEAPTENSTGVQDCYRGDGQSYRGTLST 1402
              YC+                            + P  + +  QDCYRG+G++Y G LS 
Sbjct: 374  VGYCS----------------------------QIPNCDMSHGQDCYRGNGKNYMGNLSQ 405

Query: 1403 TITGRTCQSWSSMTPHWHRRIPLYYPNAG-LTRNYCRNPDAEIR-PWCYTMDPSVRWEYC 1460
            T +G TC  W       HR I  + P+A  L  NYCRNPD +   PWCYT +P + W+YC
Sbjct: 406  TRSGLTCSMWDKNMEDLHRHI-FWEPDASKLNENYCRNPDDDAHGPWCYTGNPLIPWDYC 464

Query: 1461 NLTRCPVTESSVLTTPTV 1478
             ++RC        TTPT+
Sbjct: 465  PISRCEGD-----TTPTI 477



 Score =  304 bits (779), Expect = 5e-82
 Identities = 159/437 (36%), Positives = 211/437 (48%), Gaps = 81/437 (18%)

Query: 1160 EQSPGVQDCYHGDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRN 1219
            E    +++C  G G+SY+G+ S T +G  CQ WSSM PH H      Y    L  NYCRN
Sbjct: 120  ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRN 179

Query: 1220 PDAEI-SPWCYTMDPNVRWEYCNLTQCPVTESSVLATSTAVSEQAPTEQSPTVQDCYHGD 1278
            P  E   PWC+T +P VR+E C++ QC   E                        C   +
Sbjct: 180  PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE------------------------CMTCN 215

Query: 1279 GQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRNPDAEIRPWCYTMD 1338
            G+SYRG    T +G+ CQ W   TPH H+   E YP+ G   NYCRNPD + RPWCYT+D
Sbjct: 216  GESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLD 275

Query: 1339 PSVRWEYCNLTQCPVMESTLLTTPTVVPVPSTELPSEEAPTENSTGVQDCYRGDGQSYRG 1398
            P  RWEYC +  C   ++T+    T VP+ +TE                C +G G+ YRG
Sbjct: 276  PHTRWEYCAIKTC--ADNTM--NDTDVPLETTE----------------CIQGQGEGYRG 315

Query: 1399 TLSTTITGRTCQSWSSMTPHWHRRIPLYYPNAGLTRNYCRNPDAEIRPWCYTMDPSVRWE 1458
            T++T   G  CQ W S  PH H   P  +    L  NYCRNPD    PWC+T DP++R  
Sbjct: 316  TVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGSESPWCFTTDPNIRVG 375

Query: 1459 YCN-LTRCPVTESSVLTTPTVAPVPSTEAPSEQAPPEKSPVVQDCYHGDGRSYRGISSTT 1517
            YC+ +  C ++                               QDCY G+G++Y G  S T
Sbjct: 376  YCSQIPNCDMSHG-----------------------------QDCYRGNGKNYMGNLSQT 406

Query: 1518 VTGRTCQSWSSMIPHWHQRTPENYPNAGLTENYCRNPDSGKQ-PWCYTTDPCVRWEYCNL 1576
             +G TC  W   +   H+        + L ENYCRNPD     PWCYT +P + W+YC +
Sbjct: 407  RSGLTCSMWDKNMEDLHRHIFWEPDASKLNENYCRNPDDDAHGPWCYTGNPLIPWDYCPI 466

Query: 1577 TQCSETESGVLETPTVV 1593
            ++C         TPT+V
Sbjct: 467  SRCEGD-----TTPTIV 478



 Score =  300 bits (767), Expect = 1e-80
 Identities = 160/432 (37%), Positives = 205/432 (47%), Gaps = 86/432 (19%)

Query: 590  EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 649
            E +  ++ C  G G+SY+GT S T +G  CQ WSSM PH HS  P  Y    L  NYCRN
Sbjct: 120  ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRN 179

Query: 650  PDAV-AAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 708
            P      P+C+T +P VR+E C++ QCS+ E                             
Sbjct: 180  PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 210

Query: 709  VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 768
               C   NG+SYRG    T +G+ CQ W   TPH H   PE YP+ G   NYCRNPD   
Sbjct: 211  ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 267

Query: 769  APYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYH 828
             P+CYT DP  RWEYC +  C+D             +   + P E           EC  
Sbjct: 268  RPWCYTLDPHTRWEYCAIKTCAD-----------NTMNDTDVPLETT---------ECIQ 307

Query: 829  GNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDPVAAPYCYT 888
            G G+ YRGT +T   G  CQ W S  PH H  TPE +    L  NYCRNPD   +P+C+T
Sbjct: 308  GQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGSESPWCFT 367

Query: 889  RDPSVRWEYCN-LTQCSDAEGTAVAPPTITPIPSLEAPSEQAPTEQRPGVQECYHGNGQS 947
             DP++R  YC+ +  C  + G                             Q+CY GNG++
Sbjct: 368  TDPNIRVGYCSQIPNCDMSHG-----------------------------QDCYRGNGKN 398

Query: 948  YQGTYFITVTGRTCQAWSSMTPHSHSRTPAYYPNAG-LIKNYCRNPDPVA-APWCYTTDP 1005
            Y G    T +G TC  W       H R   + P+A  L +NYCRNPD  A  PWCYT +P
Sbjct: 399  YMGNLSQTRSGLTCSMWDKNMEDLH-RHIFWEPDASKLNENYCRNPDDDAHGPWCYTGNP 457

Query: 1006 SVRWEYCNLTRC 1017
             + W+YC ++RC
Sbjct: 458  LIPWDYCPISRC 469



 Score =  295 bits (755), Expect = 3e-79
 Identities = 159/432 (36%), Positives = 204/432 (47%), Gaps = 86/432 (19%)

Query: 134 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 193
           E +  ++ C  G G+SY+GT S T +G  CQ WSSM PH HS  P  Y    L  NYCRN
Sbjct: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRN 179

Query: 194 PDAV-AAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 252
           P      P+C+T +P VR+E C++ QCS+ E                             
Sbjct: 180 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 210

Query: 253 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 312
              C   NG+SYRG    T +G+ CQ W   TPH H   PE YP+ G   NYCRNPD   
Sbjct: 211 ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 267

Query: 313 APYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYH 372
            P+CYT DP  RWEYC +  C+D             +   + P E           EC  
Sbjct: 268 RPWCYTLDPHTRWEYCAIKTCAD-----------NTMNDTDVPLETT---------ECIQ 307

Query: 373 GNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYT 432
           G G+ YRGT +T   G  CQ W S  PH H  TPE +    L  NYCRNPD   +P+C+T
Sbjct: 308 GQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGSESPWCFT 367

Query: 433 RDPGVRWEYCN-LTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQS 491
            DP +R  YC+ +  C  + G                             Q+CY GNG++
Sbjct: 368 TDPNIRVGYCSQIPNCDMSHG-----------------------------QDCYRGNGKN 398

Query: 492 YRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAG-LIMNYCRNPDAVA-APYCYTRDP 549
           Y G  S T +G TC  W       H R   + P+A  L  NYCRNPD  A  P+CYT +P
Sbjct: 399 YMGNLSQTRSGLTCSMWDKNMEDLH-RHIFWEPDASKLNENYCRNPDDDAHGPWCYTGNP 457

Query: 550 GVRWEYCNLTQC 561
            + W+YC +++C
Sbjct: 458 LIPWDYCPISRC 469



 Score =  295 bits (755), Expect = 3e-79
 Identities = 159/432 (36%), Positives = 204/432 (47%), Gaps = 86/432 (19%)

Query: 248 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 307
           E +  ++ C  G G+SY+GT S T +G  CQ WSSM PH HS  P  Y    L  NYCRN
Sbjct: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRN 179

Query: 308 PDAV-AAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 366
           P      P+C+T +P VR+E C++ QCS+ E                             
Sbjct: 180 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 210

Query: 367 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 426
              C   NG+SYRG    T +G+ CQ W   TPH H   PE YP+ G   NYCRNPD   
Sbjct: 211 ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 267

Query: 427 APYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYH 486
            P+CYT DP  RWEYC +  C+D             +   + P E           EC  
Sbjct: 268 RPWCYTLDPHTRWEYCAIKTCAD-----------NTMNDTDVPLETT---------ECIQ 307

Query: 487 GNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYT 546
           G G+ YRGT +T   G  CQ W S  PH H  TPE +    L  NYCRNPD   +P+C+T
Sbjct: 308 GQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGSESPWCFT 367

Query: 547 RDPGVRWEYCN-LTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQS 605
            DP +R  YC+ +  C  + G                             Q+CY GNG++
Sbjct: 368 TDPNIRVGYCSQIPNCDMSHG-----------------------------QDCYRGNGKN 398

Query: 606 YRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAG-LIMNYCRNPDAVA-APYCYTRDP 663
           Y G  S T +G TC  W       H R   + P+A  L  NYCRNPD  A  P+CYT +P
Sbjct: 399 YMGNLSQTRSGLTCSMWDKNMEDLH-RHIFWEPDASKLNENYCRNPDDDAHGPWCYTGNP 457

Query: 664 GVRWEYCNLTQC 675
            + W+YC +++C
Sbjct: 458 LIPWDYCPISRC 469



 Score =  295 bits (755), Expect = 3e-79
 Identities = 159/432 (36%), Positives = 204/432 (47%), Gaps = 86/432 (19%)

Query: 362 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 421
           E +  ++ C  G G+SY+GT S T +G  CQ WSSM PH HS  P  Y    L  NYCRN
Sbjct: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRN 179

Query: 422 PDAV-AAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 480
           P      P+C+T +P VR+E C++ QCS+ E                             
Sbjct: 180 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 210

Query: 481 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 540
              C   NG+SYRG    T +G+ CQ W   TPH H   PE YP+ G   NYCRNPD   
Sbjct: 211 ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 267

Query: 541 APYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYH 600
            P+CYT DP  RWEYC +  C+D             +   + P E           EC  
Sbjct: 268 RPWCYTLDPHTRWEYCAIKTCAD-----------NTMNDTDVPLETT---------ECIQ 307

Query: 601 GNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYT 660
           G G+ YRGT +T   G  CQ W S  PH H  TPE +    L  NYCRNPD   +P+C+T
Sbjct: 308 GQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGSESPWCFT 367

Query: 661 RDPGVRWEYCN-LTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQS 719
            DP +R  YC+ +  C  + G                             Q+CY GNG++
Sbjct: 368 TDPNIRVGYCSQIPNCDMSHG-----------------------------QDCYRGNGKN 398

Query: 720 YRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAG-LIMNYCRNPDAVA-APYCYTRDP 777
           Y G  S T +G TC  W       H R   + P+A  L  NYCRNPD  A  P+CYT +P
Sbjct: 399 YMGNLSQTRSGLTCSMWDKNMEDLH-RHIFWEPDASKLNENYCRNPDDDAHGPWCYTGNP 457

Query: 778 GVRWEYCNLTQC 789
            + W+YC +++C
Sbjct: 458 LIPWDYCPISRC 469



 Score =  293 bits (749), Expect = 2e-78
 Identities = 157/432 (36%), Positives = 205/432 (47%), Gaps = 86/432 (19%)

Query: 20  EQSHVVQDCYHGDGQSYRGTYSTTVTGRTCQAWSSMTPHQHNRTTENYPNAGLIMNYCRN 79
           E    +++C  G G+SY+GT S T +G  CQ WSSM PH+H+    +Y    L  NYCRN
Sbjct: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRN 179

Query: 80  PDAV-AAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 138
           P      P+C+T +P VR+E C++ QCS+ E                             
Sbjct: 180 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 210

Query: 139 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 198
              C   NG+SYRG    T +G+ CQ W   TPH H   PE YP+ G   NYCRNPD   
Sbjct: 211 ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 267

Query: 199 APYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYH 258
            P+CYT DP  RWEYC +  C+D             +   + P E           EC  
Sbjct: 268 RPWCYTLDPHTRWEYCAIKTCAD-----------NTMNDTDVPLETT---------ECIQ 307

Query: 259 GNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYT 318
           G G+ YRGT +T   G  CQ W S  PH H  TPE +    L  NYCRNPD   +P+C+T
Sbjct: 308 GQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGSESPWCFT 367

Query: 319 RDPGVRWEYCN-LTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQS 377
            DP +R  YC+ +  C  + G                             Q+CY GNG++
Sbjct: 368 TDPNIRVGYCSQIPNCDMSHG-----------------------------QDCYRGNGKN 398

Query: 378 YRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAG-LIMNYCRNPDAVA-APYCYTRDP 435
           Y G  S T +G TC  W       H R   + P+A  L  NYCRNPD  A  P+CYT +P
Sbjct: 399 YMGNLSQTRSGLTCSMWDKNMEDLH-RHIFWEPDASKLNENYCRNPDDDAHGPWCYTGNP 457

Query: 436 GVRWEYCNLTQC 447
            + W+YC +++C
Sbjct: 458 LIPWDYCPISRC 469



 Score =  291 bits (746), Expect = 3e-78
 Identities = 154/430 (35%), Positives = 198/430 (46%), Gaps = 82/430 (19%)

Query: 704  EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 763
            E +  ++ C  G G+SY+GT S T +G  CQ WSSM PH HS  P  Y    L  NYCRN
Sbjct: 120  ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRN 179

Query: 764  PDAV-AAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 822
            P      P+C+T +P VR+E C++ QCS+ E                             
Sbjct: 180  PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 210

Query: 823  VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDPVA 882
               C   NG+SYRG    T +G+ CQ W   TPH H   PE YP+ G   NYCRNPD   
Sbjct: 211  ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 267

Query: 883  APYCYTRDPSVRWEYCNLTQCSDAEGTAVAPPTITPIPSLEAPSEQAPTEQRPGVQECYH 942
             P+CYT DP  RWEYC +  C+D             +   + P E           EC  
Sbjct: 268  RPWCYTLDPHTRWEYCAIKTCAD-----------NTMNDTDVPLETT---------ECIQ 307

Query: 943  GNGQSYQGTYFITVTGRTCQAWSSMTPHSHSRTPAYYPNAGLIKNYCRNPDPVAAPWCYT 1002
            G G+ Y+GT      G  CQ W S  PH H  TP  +    L +NYCRNPD   +PWC+T
Sbjct: 308  GQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGSESPWCFT 367

Query: 1003 TDPSVRWEYCNLTRCSDAEWTAFVPPNVILAPSLEAFFEQALTEETPGVQDCYYHYGQSY 1062
            TDP++R  YC+              PN  ++                  QDCY   G++Y
Sbjct: 368  TDPNIRVGYCSQI------------PNCDMSHG----------------QDCYRGNGKNY 399

Query: 1063 RGTYSTTVTGRTCQAWSSMTPHQHSRTPENYPNAGLTRNYCRNPDAEIR-PWCYTMDPSV 1121
             G  S T +G TC  W       H         + L  NYCRNPD +   PWCYT +P +
Sbjct: 400  MGNLSQTRSGLTCSMWDKNMEDLHRHIFWEPDASKLNENYCRNPDDDAHGPWCYTGNPLI 459

Query: 1122 RWEYCNLTQC 1131
             W+YC +++C
Sbjct: 460  PWDYCPISRC 469



 Score =  221 bits (563), Expect = 6e-57
 Identities = 118/318 (37%), Positives = 154/318 (48%), Gaps = 55/318 (17%)

Query: 19  PEQSHVVQDCYHGDGQSYRGTYSTTVTGRTCQAWSSMTPHQHNRTTENYPNAGLIMNYCR 78
           P+ S V  +C   +G+SYRG    T +G+ CQ W   TPH+H    E YP+ G   NYCR
Sbjct: 204 PQCSEV--ECMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCR 261

Query: 79  NPDAVAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 138
           NPD    P+CYT DP  RWEYC +  C+D             +   + P E         
Sbjct: 262 NPDGQPRPWCYTLDPHTRWEYCAIKTCAD-----------NTMNDTDVPLETT------- 303

Query: 139 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 198
             EC  G G+ YRGT +T   G  CQ W S  PH H  TPE +    L  NYCRNPD   
Sbjct: 304 --ECIQGQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGSE 361

Query: 199 APYCYTRDPGVRWEYCN-LTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECY 257
           +P+C+T DP +R  YC+ +  C  + G                             Q+CY
Sbjct: 362 SPWCFTTDPNIRVGYCSQIPNCDMSHG-----------------------------QDCY 392

Query: 258 HGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAG-LIMNYCRNPDAVA-APY 315
            GNG++Y G  S T +G TC  W       H R   + P+A  L  NYCRNPD  A  P+
Sbjct: 393 RGNGKNYMGNLSQTRSGLTCSMWDKNMEDLH-RHIFWEPDASKLNENYCRNPDDDAHGPW 451

Query: 316 CYTRDPGVRWEYCNLTQC 333
           CYT +P + W+YC +++C
Sbjct: 452 CYTGNPLIPWDYCPISRC 469


>gi|58533170 hepatocyte growth factor isoform 3 precursor [Homo
            sapiens]
          Length = 723

 Score =  442 bits (1136), Expect = e-123
 Identities = 251/672 (37%), Positives = 326/672 (48%), Gaps = 98/672 (14%)

Query: 1380 ENSTGVQDCYRGDGQSYRGTLSTTITGRTCQSWSSMTPHWHRRIPLYYPNAGLTRNYCRN 1439
            EN   +++C  G G+SY+GT+S T +G  CQ WSSM PH H      Y    L  NYCRN
Sbjct: 120  ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYCRN 174

Query: 1440 PDAEIR-PWCYTMDPSVRWEYCNLTRCPVTESSVLTTPTVAPVPSTEAPSEQAPPEKSPV 1498
            P  E   PWC+T +P VR+E C++ +C   E                             
Sbjct: 175  PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 205

Query: 1499 VQDCYHGDGRSYRGISSTTVTGRTCQSWSSMIPHWHQRTPENYPNAGLTENYCRNPDSGK 1558
               C   +G SYRG+   T +G+ CQ W    PH H+  PE YP+ G  +NYCRNPD   
Sbjct: 206  ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 262

Query: 1559 QPWCYTTDPCVRWEYCNLTQCSETESGVLETPTVVPVPSMEAHSEAAPTEQTPVVRQCYH 1618
            +PWCYT DP  RWEYC +  C++         T VP+ + E                C  
Sbjct: 263  RPWCYTLDPHTRWEYCAIKTCADNTM----NDTDVPLETTE----------------CIQ 302

Query: 1619 GNGQSYRGTFSTTVTGRTCQSWSSMTPHRHQRTPENYPNDGLTMNYCRNPDADTGPWCFT 1678
            G G+ YRGT +T   G  CQ W S  PH H  TPEN+    L  NYCRNPD    PWCFT
Sbjct: 303  GQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGSESPWCFT 362

Query: 1679 MDPSIRWEYCNLTRCSDTEGTVVAPPTVIQVPSLGPPSEQDCMFGNGKGYRGKKATTVTG 1738
             DP+IR  YC+                  Q+P+      QDC  GNGK Y G  + T +G
Sbjct: 363  TDPNIRVGYCS------------------QIPNCDMSHGQDCYRGNGKNYMGNLSQTRSG 404

Query: 1739 TPCQEW--AAQEPHRHSTFIPGTNKWAGLEKNYCRNPDGDINGPWCYTMNPRKLFDYCDI 1796
              C  W    ++ HRH  + P  +K   L +NYCRNPD D +GPWCYT NP   +DYC I
Sbjct: 405  LTCSMWDKNMEDLHRHIFWEPDASK---LNENYCRNPDDDAHGPWCYTGNPLIPWDYCPI 461

Query: 1797 PLCASSS----FDCGKPQVEPKKCPGSIVGGCVAHPHSWPWQVSLRTRFGKHFCGGTLIS 1852
              C   +     +   P +   K     V   +    +  W VSLR R  KH CGG+LI 
Sbjct: 462  SRCEGDTTPTIVNLDHPVISCAKTKQLRVVNGIPTRTNIGWMVSLRYR-NKHICGGSLIK 520

Query: 1853 PEWVLTAAHCLKKSSRPSSYKVILGAHQEVNL--ESHVQEIEVSRLFLEPTQADIALLKL 1910
              WVLTA  C   S     Y+  LG H       E   Q + VS+L   P  +D+ L+KL
Sbjct: 521  ESWVLTARQCF-PSRDLKDYEAWLGIHDVHGRGDEKCKQVLNVSQLVYGPEGSDLVLMKL 579

Query: 1911 SRPAVITDKVMPACLPSPDYMVTARTECYITGWGETQGTFGTGLLKEAQLLVIENEVCNH 1970
            +RPAV+ D V    LP+    +  +T C + GWG T      GLL+ A L ++ NE C+ 
Sbjct: 580  ARPAVLDDFVSTIDLPNYGCTIPEKTSCSVYGWGYTGLINYDGLLRVAHLYIMGNEKCSQ 639

Query: 1971 Y---------KYICAEHLARGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPG 2021
            +           ICA     G+  C+GD GGPLVC +    ++ GV   G GCA PN+PG
Sbjct: 640  HHRGKVTLNESEICAGAEKIGSGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPG 699

Query: 2022 VYARVSRFVTWI 2033
            ++ RV+ +  WI
Sbjct: 700  IFVRVAYYAKWI 711



 Score =  311 bits (796), Expect = 5e-84
 Identities = 160/436 (36%), Positives = 208/436 (47%), Gaps = 84/436 (19%)

Query: 932  EQRPGVQECYHGNGQSYQGTYFITVTGRTCQAWSSMTPHSHSRTPAYYPNAGLIKNYCRN 991
            E +  ++ C  G G+SY+GT  IT +G  CQ WSSM PH HS     Y    L +NYCRN
Sbjct: 120  ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYCRN 174

Query: 992  P-DPVAAPWCYTTDPSVRWEYCNLTRCSDAEWTAFVPPNVILAPSLEAFFEQALTEETPG 1050
            P      PWC+T++P VR+E C++ +CS+ E                             
Sbjct: 175  PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 205

Query: 1051 VQDCYYHYGQSYRGTYSTTVTGRTCQAWSSMTPHQHSRTPENYPNAGLTRNYCRNPDAEI 1110
               C    G+SYRG    T +G+ CQ W   TPH+H   PE YP+ G   NYCRNPD + 
Sbjct: 206  ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 262

Query: 1111 RPWCYTMDPSVRWEYCNLTQCLVTESSVLATLTVVPDPSTEASSEEAPTEQSPGVQDCYH 1170
            RPWCYT+DP  RWEYC +  C                     +  + P E +    +C  
Sbjct: 263  RPWCYTLDPHTRWEYCAIKTC----------------ADNTMNDTDVPLETT----ECIQ 302

Query: 1171 GDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRNPDAEISPWCYT 1230
            G G+ YRG+ +T   G  CQ W S  PH H  T E +    L  NYCRNPD   SPWC+T
Sbjct: 303  GQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGSESPWCFT 362

Query: 1231 MDPNVRWEYCNLTQCPVTESSVLATSTAVSEQAPTEQSPTVQDCYHGDGQSYRGSFSTTV 1290
             DPN+R  YC+                    Q P       QDCY G+G++Y G+ S T 
Sbjct: 363  TDPNIRVGYCS--------------------QIPNCDMSHGQDCYRGNGKNYMGNLSQTR 402

Query: 1291 TGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRNPDAEIR-PWCYTMDPSVRWEYCNLT 1349
            +G TC  W       H+          L  NYCRNPD +   PWCYT +P + W+YC ++
Sbjct: 403  SGLTCSMWDKNMEDLHRHIFWEPDASKLNENYCRNPDDDAHGPWCYTGNPLIPWDYCPIS 462

Query: 1350 QCPVMESTLLTTPTVV 1365
            +C        TTPT+V
Sbjct: 463  RCEGD-----TTPTIV 473



 Score =  308 bits (789), Expect = 4e-83
 Identities = 164/438 (37%), Positives = 213/438 (48%), Gaps = 86/438 (19%)

Query: 1044 LTEETPGVQDCYYHYGQSYRGTYSTTVTGRTCQAWSSMTPHQHSRTPENYPNAGLTRNYC 1103
            L E    +++C    G+SY+GT S T +G  CQ WSSM PH+HS     Y    L  NYC
Sbjct: 118  LYENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYC 172

Query: 1104 RNPDAEI-RPWCYTMDPSVRWEYCNLTQCLVTESSVLATLTVVPDPSTEASSEEAPTEQS 1162
            RNP  E   PWC+T +P VR+E C++ QC   E                           
Sbjct: 173  RNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE--------------------------- 205

Query: 1163 PGVQDCYHGDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRNPDA 1222
                 C   +G+SYRG    T +G+ CQ W   TPH H+   E YP+ G   NYCRNPD 
Sbjct: 206  -----CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDG 260

Query: 1223 EISPWCYTMDPNVRWEYCNLTQCPVTESSVLATSTAVSEQAPTEQSPTVQDCYHGDGQSY 1282
            +  PWCYT+DP+ RWEYC +  C        A +T      P E +    +C  G G+ Y
Sbjct: 261  QPRPWCYTLDPHTRWEYCAIKTC--------ADNTMNDTDVPLETT----ECIQGQGEGY 308

Query: 1283 RGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRNPDAEIRPWCYTMDPSVR 1342
            RG+ +T   G  CQ W S  PH H  T E +    L  NYCRNPD    PWC+T DP++R
Sbjct: 309  RGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGSESPWCFTTDPNIR 368

Query: 1343 WEYCNLTQCPVMESTLLTTPTVVPVPSTELPSEEAPTENSTGVQDCYRGDGQSYRGTLST 1402
              YC+                            + P  + +  QDCYRG+G++Y G LS 
Sbjct: 369  VGYCS----------------------------QIPNCDMSHGQDCYRGNGKNYMGNLSQ 400

Query: 1403 TITGRTCQSWSSMTPHWHRRIPLYYPNAG-LTRNYCRNPDAEIR-PWCYTMDPSVRWEYC 1460
            T +G TC  W       HR I  + P+A  L  NYCRNPD +   PWCYT +P + W+YC
Sbjct: 401  TRSGLTCSMWDKNMEDLHRHI-FWEPDASKLNENYCRNPDDDAHGPWCYTGNPLIPWDYC 459

Query: 1461 NLTRCPVTESSVLTTPTV 1478
             ++RC        TTPT+
Sbjct: 460  PISRCEGD-----TTPTI 472



 Score =  301 bits (770), Expect = 6e-81
 Identities = 159/437 (36%), Positives = 211/437 (48%), Gaps = 86/437 (19%)

Query: 1160 EQSPGVQDCYHGDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRN 1219
            E    +++C  G G+SY+G+ S T +G  CQ WSSM PH H      Y    L  NYCRN
Sbjct: 120  ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYCRN 174

Query: 1220 PDAEI-SPWCYTMDPNVRWEYCNLTQCPVTESSVLATSTAVSEQAPTEQSPTVQDCYHGD 1278
            P  E   PWC+T +P VR+E C++ QC   E                        C   +
Sbjct: 175  PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE------------------------CMTCN 210

Query: 1279 GQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRNPDAEIRPWCYTMD 1338
            G+SYRG    T +G+ CQ W   TPH H+   E YP+ G   NYCRNPD + RPWCYT+D
Sbjct: 211  GESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLD 270

Query: 1339 PSVRWEYCNLTQCPVMESTLLTTPTVVPVPSTELPSEEAPTENSTGVQDCYRGDGQSYRG 1398
            P  RWEYC +  C   ++T+    T VP+ +TE                C +G G+ YRG
Sbjct: 271  PHTRWEYCAIKTC--ADNTM--NDTDVPLETTE----------------CIQGQGEGYRG 310

Query: 1399 TLSTTITGRTCQSWSSMTPHWHRRIPLYYPNAGLTRNYCRNPDAEIRPWCYTMDPSVRWE 1458
            T++T   G  CQ W S  PH H   P  +    L  NYCRNPD    PWC+T DP++R  
Sbjct: 311  TVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGSESPWCFTTDPNIRVG 370

Query: 1459 YCN-LTRCPVTESSVLTTPTVAPVPSTEAPSEQAPPEKSPVVQDCYHGDGRSYRGISSTT 1517
            YC+ +  C ++                               QDCY G+G++Y G  S T
Sbjct: 371  YCSQIPNCDMSHG-----------------------------QDCYRGNGKNYMGNLSQT 401

Query: 1518 VTGRTCQSWSSMIPHWHQRTPENYPNAGLTENYCRNPDSGKQ-PWCYTTDPCVRWEYCNL 1576
             +G TC  W   +   H+        + L ENYCRNPD     PWCYT +P + W+YC +
Sbjct: 402  RSGLTCSMWDKNMEDLHRHIFWEPDASKLNENYCRNPDDDAHGPWCYTGNPLIPWDYCPI 461

Query: 1577 TQCSETESGVLETPTVV 1593
            ++C         TPT+V
Sbjct: 462  SRCEGD-----TTPTIV 473



 Score =  293 bits (750), Expect = 1e-78
 Identities = 159/432 (36%), Positives = 204/432 (47%), Gaps = 91/432 (21%)

Query: 590  EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 649
            E +  ++ C  G G+SY+GT S T +G  CQ WSSM PH HS     Y    L  NYCRN
Sbjct: 120  ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYCRN 174

Query: 650  PDAV-AAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 708
            P      P+C+T +P VR+E C++ QCS+ E                             
Sbjct: 175  PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 205

Query: 709  VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 768
               C   NG+SYRG    T +G+ CQ W   TPH H   PE YP+ G   NYCRNPD   
Sbjct: 206  ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 262

Query: 769  APYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYH 828
             P+CYT DP  RWEYC +  C+D             +   + P E           EC  
Sbjct: 263  RPWCYTLDPHTRWEYCAIKTCAD-----------NTMNDTDVPLETT---------ECIQ 302

Query: 829  GNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDPVAAPYCYT 888
            G G+ YRGT +T   G  CQ W S  PH H  TPE +    L  NYCRNPD   +P+C+T
Sbjct: 303  GQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGSESPWCFT 362

Query: 889  RDPSVRWEYCN-LTQCSDAEGTAVAPPTITPIPSLEAPSEQAPTEQRPGVQECYHGNGQS 947
             DP++R  YC+ +  C  + G                             Q+CY GNG++
Sbjct: 363  TDPNIRVGYCSQIPNCDMSHG-----------------------------QDCYRGNGKN 393

Query: 948  YQGTYFITVTGRTCQAWSSMTPHSHSRTPAYYPNAG-LIKNYCRNPDPVA-APWCYTTDP 1005
            Y G    T +G TC  W       H R   + P+A  L +NYCRNPD  A  PWCYT +P
Sbjct: 394  YMGNLSQTRSGLTCSMWDKNMEDLH-RHIFWEPDASKLNENYCRNPDDDAHGPWCYTGNP 452

Query: 1006 SVRWEYCNLTRC 1017
             + W+YC ++RC
Sbjct: 453  LIPWDYCPISRC 464



 Score =  288 bits (738), Expect = 3e-77
 Identities = 158/432 (36%), Positives = 203/432 (46%), Gaps = 91/432 (21%)

Query: 134 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 193
           E +  ++ C  G G+SY+GT S T +G  CQ WSSM PH HS     Y    L  NYCRN
Sbjct: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYCRN 174

Query: 194 PDAV-AAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 252
           P      P+C+T +P VR+E C++ QCS+ E                             
Sbjct: 175 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 205

Query: 253 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 312
              C   NG+SYRG    T +G+ CQ W   TPH H   PE YP+ G   NYCRNPD   
Sbjct: 206 ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 262

Query: 313 APYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYH 372
            P+CYT DP  RWEYC +  C+D             +   + P E           EC  
Sbjct: 263 RPWCYTLDPHTRWEYCAIKTCAD-----------NTMNDTDVPLETT---------ECIQ 302

Query: 373 GNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYT 432
           G G+ YRGT +T   G  CQ W S  PH H  TPE +    L  NYCRNPD   +P+C+T
Sbjct: 303 GQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGSESPWCFT 362

Query: 433 RDPGVRWEYCN-LTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQS 491
            DP +R  YC+ +  C  + G                             Q+CY GNG++
Sbjct: 363 TDPNIRVGYCSQIPNCDMSHG-----------------------------QDCYRGNGKN 393

Query: 492 YRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAG-LIMNYCRNPDAVA-APYCYTRDP 549
           Y G  S T +G TC  W       H R   + P+A  L  NYCRNPD  A  P+CYT +P
Sbjct: 394 YMGNLSQTRSGLTCSMWDKNMEDLH-RHIFWEPDASKLNENYCRNPDDDAHGPWCYTGNP 452

Query: 550 GVRWEYCNLTQC 561
            + W+YC +++C
Sbjct: 453 LIPWDYCPISRC 464



 Score =  288 bits (738), Expect = 3e-77
 Identities = 158/432 (36%), Positives = 203/432 (46%), Gaps = 91/432 (21%)

Query: 248 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 307
           E +  ++ C  G G+SY+GT S T +G  CQ WSSM PH HS     Y    L  NYCRN
Sbjct: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYCRN 174

Query: 308 PDAV-AAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 366
           P      P+C+T +P VR+E C++ QCS+ E                             
Sbjct: 175 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 205

Query: 367 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 426
              C   NG+SYRG    T +G+ CQ W   TPH H   PE YP+ G   NYCRNPD   
Sbjct: 206 ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 262

Query: 427 APYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYH 486
            P+CYT DP  RWEYC +  C+D             +   + P E           EC  
Sbjct: 263 RPWCYTLDPHTRWEYCAIKTCAD-----------NTMNDTDVPLETT---------ECIQ 302

Query: 487 GNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYT 546
           G G+ YRGT +T   G  CQ W S  PH H  TPE +    L  NYCRNPD   +P+C+T
Sbjct: 303 GQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGSESPWCFT 362

Query: 547 RDPGVRWEYCN-LTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQS 605
            DP +R  YC+ +  C  + G                             Q+CY GNG++
Sbjct: 363 TDPNIRVGYCSQIPNCDMSHG-----------------------------QDCYRGNGKN 393

Query: 606 YRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAG-LIMNYCRNPDAVA-APYCYTRDP 663
           Y G  S T +G TC  W       H R   + P+A  L  NYCRNPD  A  P+CYT +P
Sbjct: 394 YMGNLSQTRSGLTCSMWDKNMEDLH-RHIFWEPDASKLNENYCRNPDDDAHGPWCYTGNP 452

Query: 664 GVRWEYCNLTQC 675
            + W+YC +++C
Sbjct: 453 LIPWDYCPISRC 464



 Score =  288 bits (738), Expect = 3e-77
 Identities = 158/432 (36%), Positives = 203/432 (46%), Gaps = 91/432 (21%)

Query: 362 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 421
           E +  ++ C  G G+SY+GT S T +G  CQ WSSM PH HS     Y    L  NYCRN
Sbjct: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYCRN 174

Query: 422 PDAV-AAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 480
           P      P+C+T +P VR+E C++ QCS+ E                             
Sbjct: 175 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 205

Query: 481 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 540
              C   NG+SYRG    T +G+ CQ W   TPH H   PE YP+ G   NYCRNPD   
Sbjct: 206 ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 262

Query: 541 APYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYH 600
            P+CYT DP  RWEYC +  C+D             +   + P E           EC  
Sbjct: 263 RPWCYTLDPHTRWEYCAIKTCAD-----------NTMNDTDVPLETT---------ECIQ 302

Query: 601 GNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYT 660
           G G+ YRGT +T   G  CQ W S  PH H  TPE +    L  NYCRNPD   +P+C+T
Sbjct: 303 GQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGSESPWCFT 362

Query: 661 RDPGVRWEYCN-LTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQS 719
            DP +R  YC+ +  C  + G                             Q+CY GNG++
Sbjct: 363 TDPNIRVGYCSQIPNCDMSHG-----------------------------QDCYRGNGKN 393

Query: 720 YRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAG-LIMNYCRNPDAVA-APYCYTRDP 777
           Y G  S T +G TC  W       H R   + P+A  L  NYCRNPD  A  P+CYT +P
Sbjct: 394 YMGNLSQTRSGLTCSMWDKNMEDLH-RHIFWEPDASKLNENYCRNPDDDAHGPWCYTGNP 452

Query: 778 GVRWEYCNLTQC 789
            + W+YC +++C
Sbjct: 453 LIPWDYCPISRC 464



 Score =  288 bits (737), Expect = 4e-77
 Identities = 157/432 (36%), Positives = 204/432 (47%), Gaps = 91/432 (21%)

Query: 20  EQSHVVQDCYHGDGQSYRGTYSTTVTGRTCQAWSSMTPHQHNRTTENYPNAGLIMNYCRN 79
           E    +++C  G G+SY+GT S T +G  CQ WSSM PH+H+     Y    L  NYCRN
Sbjct: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYCRN 174

Query: 80  PDAV-AAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 138
           P      P+C+T +P VR+E C++ QCS+ E                             
Sbjct: 175 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 205

Query: 139 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 198
              C   NG+SYRG    T +G+ CQ W   TPH H   PE YP+ G   NYCRNPD   
Sbjct: 206 ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 262

Query: 199 APYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYH 258
            P+CYT DP  RWEYC +  C+D             +   + P E           EC  
Sbjct: 263 RPWCYTLDPHTRWEYCAIKTCAD-----------NTMNDTDVPLETT---------ECIQ 302

Query: 259 GNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVAAPYCYT 318
           G G+ YRGT +T   G  CQ W S  PH H  TPE +    L  NYCRNPD   +P+C+T
Sbjct: 303 GQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGSESPWCFT 362

Query: 319 RDPGVRWEYCN-LTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGNGQS 377
            DP +R  YC+ +  C  + G                             Q+CY GNG++
Sbjct: 363 TDPNIRVGYCSQIPNCDMSHG-----------------------------QDCYRGNGKN 393

Query: 378 YRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAG-LIMNYCRNPDAVA-APYCYTRDP 435
           Y G  S T +G TC  W       H R   + P+A  L  NYCRNPD  A  P+CYT +P
Sbjct: 394 YMGNLSQTRSGLTCSMWDKNMEDLH-RHIFWEPDASKLNENYCRNPDDDAHGPWCYTGNP 452

Query: 436 GVRWEYCNLTQC 447
            + W+YC +++C
Sbjct: 453 LIPWDYCPISRC 464



 Score =  285 bits (729), Expect = 3e-76
 Identities = 153/430 (35%), Positives = 197/430 (45%), Gaps = 87/430 (20%)

Query: 704  EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 763
            E +  ++ C  G G+SY+GT S T +G  CQ WSSM PH HS     Y    L  NYCRN
Sbjct: 120  ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYCRN 174

Query: 764  PDAV-AAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 822
            P      P+C+T +P VR+E C++ QCS+ E                             
Sbjct: 175  PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 205

Query: 823  VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDPVA 882
               C   NG+SYRG    T +G+ CQ W   TPH H   PE YP+ G   NYCRNPD   
Sbjct: 206  ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 262

Query: 883  APYCYTRDPSVRWEYCNLTQCSDAEGTAVAPPTITPIPSLEAPSEQAPTEQRPGVQECYH 942
             P+CYT DP  RWEYC +  C+D             +   + P E           EC  
Sbjct: 263  RPWCYTLDPHTRWEYCAIKTCAD-----------NTMNDTDVPLETT---------ECIQ 302

Query: 943  GNGQSYQGTYFITVTGRTCQAWSSMTPHSHSRTPAYYPNAGLIKNYCRNPDPVAAPWCYT 1002
            G G+ Y+GT      G  CQ W S  PH H  TP  +    L +NYCRNPD   +PWC+T
Sbjct: 303  GQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGSESPWCFT 362

Query: 1003 TDPSVRWEYCNLTRCSDAEWTAFVPPNVILAPSLEAFFEQALTEETPGVQDCYYHYGQSY 1062
            TDP++R  YC+              PN  ++                  QDCY   G++Y
Sbjct: 363  TDPNIRVGYCSQI------------PNCDMSHG----------------QDCYRGNGKNY 394

Query: 1063 RGTYSTTVTGRTCQAWSSMTPHQHSRTPENYPNAGLTRNYCRNPDAEIR-PWCYTMDPSV 1121
             G  S T +G TC  W       H         + L  NYCRNPD +   PWCYT +P +
Sbjct: 395  MGNLSQTRSGLTCSMWDKNMEDLHRHIFWEPDASKLNENYCRNPDDDAHGPWCYTGNPLI 454

Query: 1122 RWEYCNLTQC 1131
             W+YC +++C
Sbjct: 455  PWDYCPISRC 464



 Score =  221 bits (563), Expect = 6e-57
 Identities = 118/318 (37%), Positives = 154/318 (48%), Gaps = 55/318 (17%)

Query: 19  PEQSHVVQDCYHGDGQSYRGTYSTTVTGRTCQAWSSMTPHQHNRTTENYPNAGLIMNYCR 78
           P+ S V  +C   +G+SYRG    T +G+ CQ W   TPH+H    E YP+ G   NYCR
Sbjct: 199 PQCSEV--ECMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCR 256

Query: 79  NPDAVAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 138
           NPD    P+CYT DP  RWEYC +  C+D             +   + P E         
Sbjct: 257 NPDGQPRPWCYTLDPHTRWEYCAIKTCAD-----------NTMNDTDVPLETT------- 298

Query: 139 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 198
             EC  G G+ YRGT +T   G  CQ W S  PH H  TPE +    L  NYCRNPD   
Sbjct: 299 --ECIQGQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGSE 356

Query: 199 APYCYTRDPGVRWEYCN-LTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECY 257
           +P+C+T DP +R  YC+ +  C  + G                             Q+CY
Sbjct: 357 SPWCFTTDPNIRVGYCSQIPNCDMSHG-----------------------------QDCY 387

Query: 258 HGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAG-LIMNYCRNPDAVA-APY 315
            GNG++Y G  S T +G TC  W       H R   + P+A  L  NYCRNPD  A  P+
Sbjct: 388 RGNGKNYMGNLSQTRSGLTCSMWDKNMEDLH-RHIFWEPDASKLNENYCRNPDDDAHGPW 446

Query: 316 CYTRDPGVRWEYCNLTQC 333
           CYT +P + W+YC +++C
Sbjct: 447 CYTGNPLIPWDYCPISRC 464


>gi|239743017 PREDICTED: hypothetical protein XP_002342719 [Homo
            sapiens]
          Length = 299

 Score =  294 bits (753), Expect = 5e-79
 Identities = 159/305 (52%), Positives = 182/305 (59%), Gaps = 45/305 (14%)

Query: 1769 YCRNPDGDINGPWCYTMNPRKLFDYCDIPLCASSSFDCGKPQVEPKKCPGSIVGGCVAHP 1828
            YCRNPDGDINGPWCY +NPRKLFDYCDIPLCASSSFDCGKPQVEPKKCP SIVGGCVAHP
Sbjct: 7    YCRNPDGDINGPWCYRVNPRKLFDYCDIPLCASSSFDCGKPQVEPKKCPRSIVGGCVAHP 66

Query: 1829 HSWPWQVSLRTRFGKHFCGGTLISPEWVLTAAHCLKKSSRPSSYKVILGAHQEVNLESHV 1888
            HSWPWQVSL T   K       + P+           S +P      L  +  V++ S  
Sbjct: 67   HSWPWQVSLTT--SKAVPAQRALGPQ----------ASKKPVEVTESLNHNFSVHIASQY 114

Query: 1889 QEIEVSRLFLEPTQADIALLKLSR-------PAVITDKVMPACLPSPDYMVTARTECYIT 1941
                +  + L P       L +S+          +T    P   P    +V  R+  +  
Sbjct: 115  ALTIIIPISLTPLAVGKLKLLMSQFRFLRGAGCSLTHLHSPRHAPPARCLVARRSFLHAA 174

Query: 1942 ------GWGETQGT-----------FGTGLLKEAQLLVIENEVCNHYKY---------IC 1975
                   W    G+            G    ++ QLLVIEN+VCN Y+Y         +C
Sbjct: 175  PSRLGLSWALEPGSGKSLFYAAHVPLGLAFSRKPQLLVIENKVCNRYEYLNGRIKSTELC 234

Query: 1976 AEHLARGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYARVSRFVTWIEG 2035
            A HLA GTDSC+GDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVY RVSRFVTWIEG
Sbjct: 235  ARHLAGGTDSCKGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTWIEG 294

Query: 2036 MMRNN 2040
            +MRNN
Sbjct: 295  VMRNN 299



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 15/34 (44%), Positives = 24/34 (70%), Gaps = 1/34 (2%)

Query: 1664 YCRNPDAD-TGPWCFTMDPSIRWEYCNLTRCSDT 1696
            YCRNPD D  GPWC+ ++P   ++YC++  C+ +
Sbjct: 7    YCRNPDGDINGPWCYRVNPRKLFDYCDIPLCASS 40



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 15/31 (48%), Positives = 23/31 (74%), Gaps = 1/31 (3%)

Query: 1216 YCRNPDAEIS-PWCYTMDPNVRWEYCNLTQC 1245
            YCRNPD +I+ PWCY ++P   ++YC++  C
Sbjct: 7    YCRNPDGDINGPWCYRVNPRKLFDYCDIPLC 37



 Score = 42.7 bits (99), Expect = 0.004
 Identities = 15/31 (48%), Positives = 22/31 (70%), Gaps = 1/31 (3%)

Query: 1102 YCRNPDAEIR-PWCYTMDPSVRWEYCNLTQC 1131
            YCRNPD +I  PWCY ++P   ++YC++  C
Sbjct: 7    YCRNPDGDINGPWCYRVNPRKLFDYCDIPLC 37



 Score = 42.7 bits (99), Expect = 0.004
 Identities = 15/31 (48%), Positives = 22/31 (70%), Gaps = 1/31 (3%)

Query: 1322 YCRNPDAEIR-PWCYTMDPSVRWEYCNLTQC 1351
            YCRNPD +I  PWCY ++P   ++YC++  C
Sbjct: 7    YCRNPDGDINGPWCYRVNPRKLFDYCDIPLC 37



 Score = 42.7 bits (99), Expect = 0.004
 Identities = 15/31 (48%), Positives = 22/31 (70%), Gaps = 1/31 (3%)

Query: 1436 YCRNPDAEIR-PWCYTMDPSVRWEYCNLTRC 1465
            YCRNPD +I  PWCY ++P   ++YC++  C
Sbjct: 7    YCRNPDGDINGPWCYRVNPRKLFDYCDIPLC 37



 Score = 41.6 bits (96), Expect = 0.008
 Identities = 15/41 (36%), Positives = 24/41 (58%), Gaps = 1/41 (2%)

Query: 988  YCRNPD-PVAAPWCYTTDPSVRWEYCNLTRCSDAEWTAFVP 1027
            YCRNPD  +  PWCY  +P   ++YC++  C+ + +    P
Sbjct: 7    YCRNPDGDINGPWCYRVNPRKLFDYCDIPLCASSSFDCGKP 47



 Score = 38.9 bits (89), Expect = 0.052
 Identities = 14/34 (41%), Positives = 21/34 (61%), Gaps = 1/34 (2%)

Query: 1550 YCRNPDSG-KQPWCYTTDPCVRWEYCNLTQCSET 1582
            YCRNPD     PWCY  +P   ++YC++  C+ +
Sbjct: 7    YCRNPDGDINGPWCYRVNPRKLFDYCDIPLCASS 40



 Score = 36.2 bits (82), Expect = 0.34
 Identities = 13/34 (38%), Positives = 22/34 (64%), Gaps = 1/34 (2%)

Query: 76  YCRNPDA-VAAPYCYTRDPGVRWEYCNLTQCSDA 108
           YCRNPD  +  P+CY  +P   ++YC++  C+ +
Sbjct: 7   YCRNPDGDINGPWCYRVNPRKLFDYCDIPLCASS 40



 Score = 36.2 bits (82), Expect = 0.34
 Identities = 13/34 (38%), Positives = 22/34 (64%), Gaps = 1/34 (2%)

Query: 190 YCRNPDA-VAAPYCYTRDPGVRWEYCNLTQCSDA 222
           YCRNPD  +  P+CY  +P   ++YC++  C+ +
Sbjct: 7   YCRNPDGDINGPWCYRVNPRKLFDYCDIPLCASS 40



 Score = 36.2 bits (82), Expect = 0.34
 Identities = 13/34 (38%), Positives = 22/34 (64%), Gaps = 1/34 (2%)

Query: 304 YCRNPDA-VAAPYCYTRDPGVRWEYCNLTQCSDA 336
           YCRNPD  +  P+CY  +P   ++YC++  C+ +
Sbjct: 7   YCRNPDGDINGPWCYRVNPRKLFDYCDIPLCASS 40



 Score = 36.2 bits (82), Expect = 0.34
 Identities = 13/34 (38%), Positives = 22/34 (64%), Gaps = 1/34 (2%)

Query: 418 YCRNPDA-VAAPYCYTRDPGVRWEYCNLTQCSDA 450
           YCRNPD  +  P+CY  +P   ++YC++  C+ +
Sbjct: 7   YCRNPDGDINGPWCYRVNPRKLFDYCDIPLCASS 40



 Score = 36.2 bits (82), Expect = 0.34
 Identities = 13/34 (38%), Positives = 22/34 (64%), Gaps = 1/34 (2%)

Query: 532 YCRNPDA-VAAPYCYTRDPGVRWEYCNLTQCSDA 564
           YCRNPD  +  P+CY  +P   ++YC++  C+ +
Sbjct: 7   YCRNPDGDINGPWCYRVNPRKLFDYCDIPLCASS 40



 Score = 36.2 bits (82), Expect = 0.34
 Identities = 13/34 (38%), Positives = 22/34 (64%), Gaps = 1/34 (2%)

Query: 646 YCRNPDA-VAAPYCYTRDPGVRWEYCNLTQCSDA 678
           YCRNPD  +  P+CY  +P   ++YC++  C+ +
Sbjct: 7   YCRNPDGDINGPWCYRVNPRKLFDYCDIPLCASS 40



 Score = 36.2 bits (82), Expect = 0.34
 Identities = 13/34 (38%), Positives = 22/34 (64%), Gaps = 1/34 (2%)

Query: 760 YCRNPDA-VAAPYCYTRDPGVRWEYCNLTQCSDA 792
           YCRNPD  +  P+CY  +P   ++YC++  C+ +
Sbjct: 7   YCRNPDGDINGPWCYRVNPRKLFDYCDIPLCASS 40



 Score = 36.2 bits (82), Expect = 0.34
 Identities = 13/34 (38%), Positives = 22/34 (64%), Gaps = 1/34 (2%)

Query: 874 YCRNPD-PVAAPYCYTRDPSVRWEYCNLTQCSDA 906
           YCRNPD  +  P+CY  +P   ++YC++  C+ +
Sbjct: 7   YCRNPDGDINGPWCYRVNPRKLFDYCDIPLCASS 40


>gi|4503635 coagulation factor II preproprotein [Homo sapiens]
          Length = 622

 Score =  238 bits (606), Expect = 6e-62
 Identities = 176/562 (31%), Positives = 245/562 (43%), Gaps = 108/562 (19%)

Query: 1574 CNLTQCSETES-GVLETPTVVPVPSMEAHSEAAPTEQTP-------VVRQCYHGNGQSYR 1625
            C    CS  E+   LE+ T   V    A   A  T +TP       +   C  G G +YR
Sbjct: 60   CVEETCSYEEAFEALESSTATDV--FWAKYTACETARTPRDKLAACLEGNCAEGLGTNYR 117

Query: 1626 GTFSTTVTGRTCQSWSSMTPHRHQRTPENYPNDGLTMNYCRNPDADT-GPWCFTMDPSIR 1684
            G  + T +G  CQ W S  PH+ +     +P   L  N+CRNPD+ T GPWC+T DP++R
Sbjct: 118  GHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGPWCYTTDPTVR 177

Query: 1685 WEYCNLTRCSDTEGTV-VAPPTVIQVPSLGPPSEQDCMFGNGKGYRGKKATTVTGTPCQE 1743
             + C++  C   + TV + P +     +L PP EQ C+   G+ Y+G+ A T  G PC  
Sbjct: 178  RQECSIPVCGQDQVTVAMTPRSEGSSVNLSPPLEQ-CVPDRGQQYQGRLAVTTHGLPCLA 236

Query: 1744 WAAQEPH---RHSTFIPGTNKWAGLEKNYCRNPDGDINGPWCYTMNPRKLFDYCDIPLC- 1799
            WA+ +     +H  F    N    L +N+CRNPDGD  G WCY       F YCD+  C 
Sbjct: 237  WASAQAKALSKHQDF----NSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCDLNYCE 292

Query: 1800 -------------------------------------ASSSFDCG-KPQVEPKK------ 1815
                                                  S   DCG +P  E K       
Sbjct: 293  EAVEEETGDGLDEDSDRAIEGRTATSEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTE 352

Query: 1816 -------CPGSIVGGCVAHPHSWPWQVSL-RTRFGKHFCGGTLISPEWVLTAAHCL---- 1863
                     G IV G  A     PWQV L R    +  CG +LIS  WVLTAAHCL    
Sbjct: 353  RELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPP 412

Query: 1864 -KKSSRPSSYKVILGAHQEVNLESHVQEIE-VSRLFLEP-------TQADIALLKLSRPA 1914
              K+   +   V +G H     E ++++I  + ++++ P          DIAL+KL +P 
Sbjct: 413  WDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPV 472

Query: 1915 VITDKVMPACLPSPDYMVTARTECY---ITGWGETQGTF----GTG---LLKEAQLLVIE 1964
              +D + P CLP  +   +     Y   +TGWG  + T+    G G   +L+   L ++E
Sbjct: 473  AFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVE 532

Query: 1965 NEVCNHYKYI-------CAEHL---ARGTDSCQGDSGGPLVCFE--KDKYILQGVTSWGL 2012
              VC     I       CA +     +  D+C+GDSGGP V      +++   G+ SWG 
Sbjct: 533  RPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGE 592

Query: 2013 GCARPNKPGVYARVSRFVTWIE 2034
            GC R  K G Y  V R   WI+
Sbjct: 593  GCDRDGKYGFYTHVFRLKKWIQ 614



 Score =  131 bits (330), Expect = 6e-30
 Identities = 69/197 (35%), Positives = 95/197 (48%), Gaps = 12/197 (6%)

Query: 1501 DCYHGDGRSYRGISSTTVTGRTCQSWSSMIPHWHQRTPENYPNAGLTENYCRNPDSGKQ- 1559
            +C  G G +YRG  + T +G  CQ W S  PH  +     +P A L EN+CRNPDS    
Sbjct: 107  NCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTG 166

Query: 1560 PWCYTTDPCVRWEYCNLTQCSETESGVLETPTVVPVPSMEAHSEAAPTEQTPVVRQCYHG 1619
            PWCYTTDP VR + C++  C + +  V  TP           SE +    +P + QC   
Sbjct: 167  PWCYTTDPTVRRQECSIPVCGQDQVTVAMTP----------RSEGSSVNLSPPLEQCVPD 216

Query: 1620 NGQSYRGTFSTTVTGRTCQSWSSMTPHRHQRTPENYPNDGLTMNYCRNPDAD-TGPWCFT 1678
             GQ Y+G  + T  G  C +W+S       +  +      L  N+CRNPD D  G WC+ 
Sbjct: 217  RGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYV 276

Query: 1679 MDPSIRWEYCNLTRCSD 1695
                  + YC+L  C +
Sbjct: 277  AGKPGDFGYCDLNYCEE 293



 Score =  125 bits (313), Expect = 6e-28
 Identities = 66/197 (33%), Positives = 92/197 (46%), Gaps = 12/197 (6%)

Query: 826  CYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDP-VAAP 884
            C  G G +YRG  + T +G  CQ W S  PH        +P A L  N+CRNPD     P
Sbjct: 108  CAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGP 167

Query: 885  YCYTRDPSVRWEYCNLTQCSDAEGTAVAPPTITPIPSLEAPSEQAPTEQRPGVQECYHGN 944
            +CYT DP+VR + C++  C   + T    P           SE +     P +++C    
Sbjct: 168  WCYTTDPTVRRQECSIPVCGQDQVTVAMTPR----------SEGSSVNLSPPLEQCVPDR 217

Query: 945  GQSYQGTYFITVTGRTCQAWSSMTPHSHSRTPAYYPNAGLIKNYCRNPD-PVAAPWCYTT 1003
            GQ YQG   +T  G  C AW+S    + S+   +     L++N+CRNPD      WCY  
Sbjct: 218  GQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVA 277

Query: 1004 DPSVRWEYCNLTRCSDA 1020
                 + YC+L  C +A
Sbjct: 278  GKPGDFGYCDLNYCEEA 294



 Score =  124 bits (312), Expect = 7e-28
 Identities = 64/187 (34%), Positives = 91/187 (48%), Gaps = 4/187 (2%)

Query: 1167 DCYHGDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRNPDAEIS- 1225
            +C  G G +YRG  + T +G  CQ W S  PH  +  +  +P   L  N+CRNPD+  + 
Sbjct: 107  NCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTG 166

Query: 1226 PWCYTMDPNVRWEYCNLTQCPVTESSVLATSTAVSEQAPTEQSPTVQDCYHGDGQSYRGS 1285
            PWCYT DP VR + C++  C   +  V    T  SE +    SP ++ C    GQ Y+G 
Sbjct: 167  PWCYTTDPTVRRQECSIPVC--GQDQVTVAMTPRSEGSSVNLSPPLEQCVPDRGQQYQGR 224

Query: 1286 FSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRNPDA-EIRPWCYTMDPSVRWE 1344
             + T  G  C +W+S       +  ++     L  N+CRNPD  E   WCY       + 
Sbjct: 225  LAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFG 284

Query: 1345 YCNLTQC 1351
            YC+L  C
Sbjct: 285  YCDLNYC 291



 Score =  122 bits (305), Expect = 5e-27
 Identities = 64/198 (32%), Positives = 95/198 (47%), Gaps = 12/198 (6%)

Query: 27  DCYHGDGQSYRGTYSTTVTGRTCQAWSSMTPHQHNRTTENYPNAGLIMNYCRNPD-AVAA 85
           +C  G G +YRG  + T +G  CQ W S  PH+    +  +P A L  N+CRNPD +   
Sbjct: 107 NCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTG 166

Query: 86  PYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHG 145
           P+CYT DP VR + C++  C   + T    P           SE +     P +++C   
Sbjct: 167 PWCYTTDPTVRRQECSIPVCGQDQVTVAMTPR----------SEGSSVNLSPPLEQCVPD 216

Query: 146 NGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDA-VAAPYCYT 204
            GQ Y+G  + T  G  C AW+S    + S+  ++     L+ N+CRNPD      +CY 
Sbjct: 217 RGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYV 276

Query: 205 RDPGVRWEYCNLTQCSDA 222
                 + YC+L  C +A
Sbjct: 277 AGKPGDFGYCDLNYCEEA 294



 Score =  121 bits (304), Expect = 6e-27
 Identities = 66/194 (34%), Positives = 90/194 (46%), Gaps = 12/194 (6%)

Query: 940  CYHGNGQSYQGTYFITVTGRTCQAWSSMTPHSHSRTPAYYPNAGLIKNYCRNPDP-VAAP 998
            C  G G +Y+G   IT +G  CQ W S  PH        +P A L +N+CRNPD     P
Sbjct: 108  CAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGP 167

Query: 999  WCYTTDPSVRWEYCNLTRCSDAEWTAFVPPNVILAPSLEAFFEQALTEETPGVQDCYYHY 1058
            WCYTTDP+VR + C++  C   + T  + P            E +    +P ++ C    
Sbjct: 168  WCYTTDPTVRRQECSIPVCGQDQVTVAMTPRS----------EGSSVNLSPPLEQCVPDR 217

Query: 1059 GQSYRGTYSTTVTGRTCQAWSSMTPHQHSRTPENYPNAGLTRNYCRNPDA-EIRPWCYTM 1117
            GQ Y+G  + T  G  C AW+S      S+  +      L  N+CRNPD  E   WCY  
Sbjct: 218  GQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVA 277

Query: 1118 DPSVRWEYCNLTQC 1131
                 + YC+L  C
Sbjct: 278  GKPGDFGYCDLNYC 291



 Score =  121 bits (303), Expect = 8e-27
 Identities = 66/195 (33%), Positives = 93/195 (47%), Gaps = 12/195 (6%)

Query: 1053 DCYYHYGQSYRGTYSTTVTGRTCQAWSSMTPHQHSRTPENYPNAGLTRNYCRNPDAEIR- 1111
            +C    G +YRG  + T +G  CQ W S  PH+       +P A L  N+CRNPD+    
Sbjct: 107  NCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTG 166

Query: 1112 PWCYTMDPSVRWEYCNLTQCLVTESSVLATLTVVPDPSTEASSEEAPTEQSPGVQDCYHG 1171
            PWCYT DP+VR + C++  C   +      +TV   P +E SS       SP ++ C   
Sbjct: 167  PWCYTTDPTVRRQECSIPVCGQDQ------VTVAMTPRSEGSS----VNLSPPLEQCVPD 216

Query: 1172 DGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRNPDA-EISPWCYT 1230
             GQ Y+G  + T  G  C +W+S       +  ++     L  N+CRNPD  E   WCY 
Sbjct: 217  RGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYV 276

Query: 1231 MDPNVRWEYCNLTQC 1245
                  + YC+L  C
Sbjct: 277  AGKPGDFGYCDLNYC 291



 Score =  120 bits (301), Expect = 1e-26
 Identities = 66/197 (33%), Positives = 95/197 (48%), Gaps = 12/197 (6%)

Query: 1387 DCYRGDGQSYRGTLSTTITGRTCQSWSSMTPHWHRRIPLYYPNAGLTRNYCRNPDAEIR- 1445
            +C  G G +YRG ++ T +G  CQ W S  PH        +P A L  N+CRNPD+    
Sbjct: 107  NCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTG 166

Query: 1446 PWCYTMDPSVRWEYCNLTRCPVTESSVLTTPTVAPVPSTEAPSEQAPPEKSPVVQDCYHG 1505
            PWCYT DP+VR + C++  C   + +V  TP           SE +    SP ++ C   
Sbjct: 167  PWCYTTDPTVRRQECSIPVCGQDQVTVAMTPR----------SEGSSVNLSPPLEQCVPD 216

Query: 1506 DGRSYRGISSTTVTGRTCQSWSSMIPHWHQRTPENYPNAGLTENYCRNPDSGKQ-PWCYT 1564
             G+ Y+G  + T  G  C +W+S       +  +      L EN+CRNPD  ++  WCY 
Sbjct: 217  RGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYV 276

Query: 1565 TDPCVRWEYCNLTQCSE 1581
                  + YC+L  C E
Sbjct: 277  AGKPGDFGYCDLNYCEE 293



 Score =  120 bits (300), Expect = 2e-26
 Identities = 64/197 (32%), Positives = 92/197 (46%), Gaps = 12/197 (6%)

Query: 142 CYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDA-VAAP 200
           C  G G +YRG  + T +G  CQ W S  PH        +P A L  N+CRNPD+    P
Sbjct: 108 CAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGP 167

Query: 201 YCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGN 260
           +CYT DP VR + C++  C   + T    P           SE +     P +++C    
Sbjct: 168 WCYTTDPTVRRQECSIPVCGQDQVTVAMTPR----------SEGSSVNLSPPLEQCVPDR 217

Query: 261 GQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDA-VAAPYCYTR 319
           GQ Y+G  + T  G  C AW+S    + S+  ++     L+ N+CRNPD      +CY  
Sbjct: 218 GQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVA 277

Query: 320 DPGVRWEYCNLTQCSDA 336
                + YC+L  C +A
Sbjct: 278 GKPGDFGYCDLNYCEEA 294



 Score =  120 bits (300), Expect = 2e-26
 Identities = 64/197 (32%), Positives = 92/197 (46%), Gaps = 12/197 (6%)

Query: 256 CYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPD-AVAAP 314
           C  G G +YRG  + T +G  CQ W S  PH        +P A L  N+CRNPD +   P
Sbjct: 108 CAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGP 167

Query: 315 YCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGN 374
           +CYT DP VR + C++  C   + T    P           SE +     P +++C    
Sbjct: 168 WCYTTDPTVRRQECSIPVCGQDQVTVAMTPR----------SEGSSVNLSPPLEQCVPDR 217

Query: 375 GQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDA-VAAPYCYTR 433
           GQ Y+G  + T  G  C AW+S    + S+  ++     L+ N+CRNPD      +CY  
Sbjct: 218 GQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVA 277

Query: 434 DPGVRWEYCNLTQCSDA 450
                + YC+L  C +A
Sbjct: 278 GKPGDFGYCDLNYCEEA 294



 Score =  120 bits (300), Expect = 2e-26
 Identities = 64/197 (32%), Positives = 92/197 (46%), Gaps = 12/197 (6%)

Query: 370 CYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDA-VAAP 428
           C  G G +YRG  + T +G  CQ W S  PH        +P A L  N+CRNPD+    P
Sbjct: 108 CAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGP 167

Query: 429 YCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGN 488
           +CYT DP VR + C++  C   + T    P           SE +     P +++C    
Sbjct: 168 WCYTTDPTVRRQECSIPVCGQDQVTVAMTPR----------SEGSSVNLSPPLEQCVPDR 217

Query: 489 GQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDA-VAAPYCYTR 547
           GQ Y+G  + T  G  C AW+S    + S+  ++     L+ N+CRNPD      +CY  
Sbjct: 218 GQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVA 277

Query: 548 DPGVRWEYCNLTQCSDA 564
                + YC+L  C +A
Sbjct: 278 GKPGDFGYCDLNYCEEA 294



 Score =  120 bits (300), Expect = 2e-26
 Identities = 64/197 (32%), Positives = 92/197 (46%), Gaps = 12/197 (6%)

Query: 484 CYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPD-AVAAP 542
           C  G G +YRG  + T +G  CQ W S  PH        +P A L  N+CRNPD +   P
Sbjct: 108 CAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGP 167

Query: 543 YCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGN 602
           +CYT DP VR + C++  C   + T    P           SE +     P +++C    
Sbjct: 168 WCYTTDPTVRRQECSIPVCGQDQVTVAMTPR----------SEGSSVNLSPPLEQCVPDR 217

Query: 603 GQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDA-VAAPYCYTR 661
           GQ Y+G  + T  G  C AW+S    + S+  ++     L+ N+CRNPD      +CY  
Sbjct: 218 GQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVA 277

Query: 662 DPGVRWEYCNLTQCSDA 678
                + YC+L  C +A
Sbjct: 278 GKPGDFGYCDLNYCEEA 294



 Score =  120 bits (300), Expect = 2e-26
 Identities = 64/197 (32%), Positives = 92/197 (46%), Gaps = 12/197 (6%)

Query: 598 CYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDA-VAAP 656
           C  G G +YRG  + T +G  CQ W S  PH        +P A L  N+CRNPD+    P
Sbjct: 108 CAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGP 167

Query: 657 YCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGN 716
           +CYT DP VR + C++  C   + T    P           SE +     P +++C    
Sbjct: 168 WCYTTDPTVRRQECSIPVCGQDQVTVAMTPR----------SEGSSVNLSPPLEQCVPDR 217

Query: 717 GQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDA-VAAPYCYTR 775
           GQ Y+G  + T  G  C AW+S    + S+  ++     L+ N+CRNPD      +CY  
Sbjct: 218 GQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVA 277

Query: 776 DPGVRWEYCNLTQCSDA 792
                + YC+L  C +A
Sbjct: 278 GKPGDFGYCDLNYCEEA 294



 Score =  120 bits (300), Expect = 2e-26
 Identities = 64/197 (32%), Positives = 92/197 (46%), Gaps = 12/197 (6%)

Query: 712 CYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPD-AVAAP 770
           C  G G +YRG  + T +G  CQ W S  PH        +P A L  N+CRNPD +   P
Sbjct: 108 CAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGP 167

Query: 771 YCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQECYHGN 830
           +CYT DP VR + C++  C   + T    P           SE +     P +++C    
Sbjct: 168 WCYTTDPTVRRQECSIPVCGQDQVTVAMTPR----------SEGSSVNLSPPLEQCVPDR 217

Query: 831 GQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPD-PVAAPYCYTR 889
           GQ Y+G  + T  G  C AW+S    + S+  ++     L+ N+CRNPD      +CY  
Sbjct: 218 GQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVA 277

Query: 890 DPSVRWEYCNLTQCSDA 906
                + YC+L  C +A
Sbjct: 278 GKPGDFGYCDLNYCEEA 294



 Score =  118 bits (295), Expect = 7e-26
 Identities = 65/195 (33%), Positives = 92/195 (47%), Gaps = 12/195 (6%)

Query: 1273 DCYHGDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRNPDAEIR- 1331
            +C  G G +YRG  + T +G  CQ W S  PH  +  +  +P   L  N+CRNPD+    
Sbjct: 107  NCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTG 166

Query: 1332 PWCYTMDPSVRWEYCNLTQCPVMESTLLTTPTVVPVPSTELPSEEAPTENSTGVQDCYRG 1391
            PWCYT DP+VR + C++  C   + T+  TP           SE +    S  ++ C   
Sbjct: 167  PWCYTTDPTVRRQECSIPVCGQDQVTVAMTPR----------SEGSSVNLSPPLEQCVPD 216

Query: 1392 DGQSYRGTLSTTITGRTCQSWSSMTPHWHRRIPLYYPNAGLTRNYCRNPDA-EIRPWCYT 1450
             GQ Y+G L+ T  G  C +W+S       +   +     L  N+CRNPD  E   WCY 
Sbjct: 217  RGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYV 276

Query: 1451 MDPSVRWEYCNLTRC 1465
                  + YC+L  C
Sbjct: 277  AGKPGDFGYCDLNYC 291



 Score = 50.4 bits (119), Expect = 2e-05
 Identities = 25/85 (29%), Positives = 39/85 (45%), Gaps = 1/85 (1%)

Query: 25  VQDCYHGDGQSYRGTYSTTVTGRTCQAWSSMTPHQHNRTTENYPNAGLIMNYCRNPDA-V 83
           ++ C    GQ Y+G  + T  G  C AW+S      ++  +      L+ N+CRNPD   
Sbjct: 210 LEQCVPDRGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDE 269

Query: 84  AAPYCYTRDPGVRWEYCNLTQCSDA 108
              +CY       + YC+L  C +A
Sbjct: 270 EGVWCYVAGKPGDFGYCDLNYCEEA 294


>gi|4505861 plasminogen activator, tissue isoform 1 preproprotein
            [Homo sapiens]
          Length = 562

 Score =  236 bits (602), Expect = 2e-61
 Identities = 163/475 (34%), Positives = 217/475 (45%), Gaps = 92/475 (19%)

Query: 1616 CYHGNGQSYRGTFSTTVTGRTCQSWSSMT----PHRHQRTPENYPNDGLTMNYCRNPDAD 1671
            CY   G SYRGT+ST  +G  C +W+S      P+  +R P+         NYCRNPD D
Sbjct: 127  CYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRR-PDAIRLGLGNHNYCRNPDRD 185

Query: 1672 TGPWCFTMDPS-IRWEYCNLTRCSDTEGTVVAPPTVIQVPSLGPPSEQDCMFGNGKGYRG 1730
            + PWC+         E+C+   CS+                       DC FGNG  YRG
Sbjct: 186  SKPWCYVFKAGKYSSEFCSTPACSE--------------------GNSDCYFGNGSAYRG 225

Query: 1731 KKATTVTGTPCQEW----------AAQEPHRHSTFIPGTNKWAGLEK-NYCRNPDGDING 1779
              + T +G  C  W           AQ P   +          GL K NYCRNPDGD   
Sbjct: 226  THSLTESGASCLPWNSMILIGKVYTAQNPSAQAL---------GLGKHNYCRNPDGDAK- 275

Query: 1780 PWCYTMNPRKL-FDYCDIPLCASSSFDCGKPQVEPKKCPGSIVGGCVAHPHSWPWQVSLR 1838
            PWC+ +  R+L ++YCD+P C++    CG  Q    +    I GG  A   S PWQ ++ 
Sbjct: 276  PWCHVLKNRRLTWEYCDVPSCST----CGLRQYSQPQF--RIKGGLFADIASHPWQAAI- 328

Query: 1839 TRFGKH--------FCGGTLISPEWVLTAAHCLKKSSRPSSYKVILGAHQEVNLESHVQE 1890
              F KH         CGG LIS  W+L+AAHC ++   P    VILG    V      Q+
Sbjct: 329  --FAKHRRSPGERFLCGGILISSCWILSAAHCFQERFPPHHLTVILGRTYRVVPGEEEQK 386

Query: 1891 IEVSRLFL------EPTQADIALLKL----SRPAVITDKVMPACLPSPDYMVTARTECYI 1940
             EV +  +      +    DIALL+L    SR A  +  V   CLP  D  +   TEC +
Sbjct: 387  FEVEKYIVHKEFDDDTYDNDIALLQLKSDSSRCAQESSVVRTVCLPPADLQLPDWTECEL 446

Query: 1941 TGWG--ETQGTFGTGLLKEAQLLVIENEVCNHY---------KYICAEHLARGT------ 1983
            +G+G  E    F +  LKEA + +  +  C              +CA     G       
Sbjct: 447  SGYGKHEALSPFYSERLKEAHVRLYPSSRCTSQHLLNRTVTDNMLCAGDTRSGGPQANLH 506

Query: 1984 DSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYARVSRFVTWIEGMMR 2038
            D+CQGDSGGPLVC    +  L G+ SWGLGC + + PGVY +V+ ++ WI   MR
Sbjct: 507  DACQGDSGGPLVCLNDGRMTLVGIISWGLGCGQKDVPGVYTKVTNYLDWIRDNMR 561



 Score =  113 bits (282), Expect = 2e-24
 Identities = 71/203 (34%), Positives = 92/203 (45%), Gaps = 42/203 (20%)

Query: 1388 CYRGDGQSYRGTLSTTITGRTCQSWSSMT----PHWHRRIPLYYPNAGLTRNYCRNPDAE 1443
            CY   G SYRGT ST  +G  C +W+S      P+  RR        G   NYCRNPD +
Sbjct: 127  CYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLG-NHNYCRNPDRD 185

Query: 1444 IRPWCYTMDPS-VRWEYCNLTRCPVTESSVLTTPTVAPVPSTEAPSEQAPPEKSPVVQDC 1502
             +PWCY         E+C+   C    S                              DC
Sbjct: 186  SKPWCYVFKAGKYSSEFCSTPACSEGNS------------------------------DC 215

Query: 1503 YHGDGRSYRGISSTTVTGRTCQSWSSMIPHWHQRTPENYPNA---GL-TENYCRNPDSGK 1558
            Y G+G +YRG  S T +G +C  W+SMI      T +N P+A   GL   NYCRNPD   
Sbjct: 216  YFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQN-PSAQALGLGKHNYCRNPDGDA 274

Query: 1559 QPWCYT-TDPCVRWEYCNLTQCS 1580
            +PWC+   +  + WEYC++  CS
Sbjct: 275  KPWCHVLKNRRLTWEYCDVPSCS 297



 Score =  113 bits (282), Expect = 2e-24
 Identities = 65/200 (32%), Positives = 87/200 (43%), Gaps = 38/200 (19%)

Query: 1054 CYYHYGQSYRGTYSTTVTGRTCQAWSSMTPHQH---SRTPENYPNAGLTRNYCRNPDAEI 1110
            CY   G SYRGT+ST  +G  C  W+S    Q     R P+         NYCRNPD + 
Sbjct: 127  CYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLGNHNYCRNPDRDS 186

Query: 1111 RPWCYTMDPS-VRWEYCNLTQCLVTESSVLATLTVVPDPSTEASSEEAPTEQSPGVQDCY 1169
            +PWCY         E+C+   C                              S G  DCY
Sbjct: 187  KPWCYVFKAGKYSSEFCSTPAC------------------------------SEGNSDCY 216

Query: 1170 HGDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGL---TRNYCRNPDAEISP 1226
             G+G +YRG+ S T +G +C  W+SM       T +      L     NYCRNPD +  P
Sbjct: 217  FGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQNPSAQALGLGKHNYCRNPDGDAKP 276

Query: 1227 WCYTM-DPNVRWEYCNLTQC 1245
            WC+ + +  + WEYC++  C
Sbjct: 277  WCHVLKNRRLTWEYCDVPSC 296



 Score =  111 bits (278), Expect = 6e-24
 Identities = 68/202 (33%), Positives = 94/202 (46%), Gaps = 42/202 (20%)

Query: 940  CYHGNGQSYQGTYFITVTGRTCQAWSSMT----PHSHSRTPAYYPNAGLIKNYCRNPDPV 995
            CY   G SY+GT+    +G  C  W+S      P+S  R  A     G   NYCRNPD  
Sbjct: 127  CYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLGN-HNYCRNPDRD 185

Query: 996  AAPWCYTTDPS-VRWEYCNLTRCSDAEWTAFVPPNVILAPSLEAFFEQALTEETPGVQDC 1054
            + PWCY         E+C+   CS+                              G  DC
Sbjct: 186  SKPWCYVFKAGKYSSEFCSTPACSE------------------------------GNSDC 215

Query: 1055 YYHYGQSYRGTYSTTVTGRTCQAWSSMTPHQHSRTPENYPNA---GLTR-NYCRNPDAEI 1110
            Y+  G +YRGT+S T +G +C  W+SM       T +N P+A   GL + NYCRNPD + 
Sbjct: 216  YFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQN-PSAQALGLGKHNYCRNPDGDA 274

Query: 1111 RPWCYTM-DPSVRWEYCNLTQC 1131
            +PWC+ + +  + WEYC++  C
Sbjct: 275  KPWCHVLKNRRLTWEYCDVPSC 296



 Score =  111 bits (278), Expect = 6e-24
 Identities = 62/192 (32%), Positives = 87/192 (45%), Gaps = 30/192 (15%)

Query: 1168 CYHGDGQSYRGSFSTTVTGRTCQSWSSMT---PHWHQRTTEYYPNGGLTRNYCRNPDAEI 1224
            CY   G SYRG++ST  +G  C +W+S       +  R  +    G    NYCRNPD + 
Sbjct: 127  CYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLGNHNYCRNPDRDS 186

Query: 1225 SPWCYTMDPN-VRWEYCNLTQCPVTESSVLATSTAVSEQAPTEQSPTVQDCYHGDGQSYR 1283
             PWCY         E+C+   C    S                      DCY G+G +YR
Sbjct: 187  KPWCYVFKAGKYSSEFCSTPACSEGNS----------------------DCYFGNGSAYR 224

Query: 1284 GSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGL---TRNYCRNPDAEIRPWCYTM-DP 1339
            G+ S T +G +C  W+SM       T +      L     NYCRNPD + +PWC+ + + 
Sbjct: 225  GTHSLTESGASCLPWNSMILIGKVYTAQNPSAQALGLGKHNYCRNPDGDAKPWCHVLKNR 284

Query: 1340 SVRWEYCNLTQC 1351
             + WEYC++  C
Sbjct: 285  RLTWEYCDVPSC 296



 Score =  110 bits (276), Expect = 1e-23
 Identities = 69/203 (33%), Positives = 94/203 (46%), Gaps = 42/203 (20%)

Query: 142 CYHGNGQSYRGTYSTTVTGRTCQAWSSMT----PHSHSRTPEYYPNAGLIMNYCRNPDAV 197
           CY   G SYRGT+ST  +G  C  W+S      P+S  R        G   NYCRNPD  
Sbjct: 127 CYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLGN-HNYCRNPDRD 185

Query: 198 AAPYCYTRDPG-VRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQEC 256
           + P+CY    G    E+C+   CS+                              G  +C
Sbjct: 186 SKPWCYVFKAGKYSSEFCSTPACSE------------------------------GNSDC 215

Query: 257 YHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLI----MNYCRNPDAVA 312
           Y GNG +YRGT+S T +G +C  W+SM       T +  P+A  +     NYCRNPD  A
Sbjct: 216 YFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQ-NPSAQALGLGKHNYCRNPDGDA 274

Query: 313 APYCYT-RDPGVRWEYCNLTQCS 334
            P+C+  ++  + WEYC++  CS
Sbjct: 275 KPWCHVLKNRRLTWEYCDVPSCS 297



 Score =  110 bits (276), Expect = 1e-23
 Identities = 69/203 (33%), Positives = 94/203 (46%), Gaps = 42/203 (20%)

Query: 256 CYHGNGQSYRGTYSTTVTGRTCQAWSSMT----PHSHSRTPEYYPNAGLIMNYCRNPDAV 311
           CY   G SYRGT+ST  +G  C  W+S      P+S  R        G   NYCRNPD  
Sbjct: 127 CYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLGN-HNYCRNPDRD 185

Query: 312 AAPYCYTRDPG-VRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQEC 370
           + P+CY    G    E+C+   CS+                              G  +C
Sbjct: 186 SKPWCYVFKAGKYSSEFCSTPACSE------------------------------GNSDC 215

Query: 371 YHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLI----MNYCRNPDAVA 426
           Y GNG +YRGT+S T +G +C  W+SM       T +  P+A  +     NYCRNPD  A
Sbjct: 216 YFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQ-NPSAQALGLGKHNYCRNPDGDA 274

Query: 427 APYCYT-RDPGVRWEYCNLTQCS 448
            P+C+  ++  + WEYC++  CS
Sbjct: 275 KPWCHVLKNRRLTWEYCDVPSCS 297



 Score =  110 bits (276), Expect = 1e-23
 Identities = 69/203 (33%), Positives = 94/203 (46%), Gaps = 42/203 (20%)

Query: 370 CYHGNGQSYRGTYSTTVTGRTCQAWSSMT----PHSHSRTPEYYPNAGLIMNYCRNPDAV 425
           CY   G SYRGT+ST  +G  C  W+S      P+S  R        G   NYCRNPD  
Sbjct: 127 CYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLGN-HNYCRNPDRD 185

Query: 426 AAPYCYTRDPG-VRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQEC 484
           + P+CY    G    E+C+   CS+                              G  +C
Sbjct: 186 SKPWCYVFKAGKYSSEFCSTPACSE------------------------------GNSDC 215

Query: 485 YHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLI----MNYCRNPDAVA 540
           Y GNG +YRGT+S T +G +C  W+SM       T +  P+A  +     NYCRNPD  A
Sbjct: 216 YFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQ-NPSAQALGLGKHNYCRNPDGDA 274

Query: 541 APYCYT-RDPGVRWEYCNLTQCS 562
            P+C+  ++  + WEYC++  CS
Sbjct: 275 KPWCHVLKNRRLTWEYCDVPSCS 297



 Score =  110 bits (276), Expect = 1e-23
 Identities = 69/203 (33%), Positives = 94/203 (46%), Gaps = 42/203 (20%)

Query: 484 CYHGNGQSYRGTYSTTVTGRTCQAWSSMT----PHSHSRTPEYYPNAGLIMNYCRNPDAV 539
           CY   G SYRGT+ST  +G  C  W+S      P+S  R        G   NYCRNPD  
Sbjct: 127 CYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLGN-HNYCRNPDRD 185

Query: 540 AAPYCYTRDPG-VRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQEC 598
           + P+CY    G    E+C+   CS+                              G  +C
Sbjct: 186 SKPWCYVFKAGKYSSEFCSTPACSE------------------------------GNSDC 215

Query: 599 YHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLI----MNYCRNPDAVA 654
           Y GNG +YRGT+S T +G +C  W+SM       T +  P+A  +     NYCRNPD  A
Sbjct: 216 YFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQ-NPSAQALGLGKHNYCRNPDGDA 274

Query: 655 APYCYT-RDPGVRWEYCNLTQCS 676
            P+C+  ++  + WEYC++  CS
Sbjct: 275 KPWCHVLKNRRLTWEYCDVPSCS 297



 Score =  110 bits (276), Expect = 1e-23
 Identities = 69/203 (33%), Positives = 94/203 (46%), Gaps = 42/203 (20%)

Query: 598 CYHGNGQSYRGTYSTTVTGRTCQAWSSMT----PHSHSRTPEYYPNAGLIMNYCRNPDAV 653
           CY   G SYRGT+ST  +G  C  W+S      P+S  R        G   NYCRNPD  
Sbjct: 127 CYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLGN-HNYCRNPDRD 185

Query: 654 AAPYCYTRDPG-VRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQEC 712
           + P+CY    G    E+C+   CS+                              G  +C
Sbjct: 186 SKPWCYVFKAGKYSSEFCSTPACSE------------------------------GNSDC 215

Query: 713 YHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLI----MNYCRNPDAVA 768
           Y GNG +YRGT+S T +G +C  W+SM       T +  P+A  +     NYCRNPD  A
Sbjct: 216 YFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQ-NPSAQALGLGKHNYCRNPDGDA 274

Query: 769 APYCYT-RDPGVRWEYCNLTQCS 790
            P+C+  ++  + WEYC++  CS
Sbjct: 275 KPWCHVLKNRRLTWEYCDVPSCS 297



 Score =  110 bits (275), Expect = 1e-23
 Identities = 69/203 (33%), Positives = 94/203 (46%), Gaps = 42/203 (20%)

Query: 712 CYHGNGQSYRGTYSTTVTGRTCQAWSSMT----PHSHSRTPEYYPNAGLIMNYCRNPDAV 767
           CY   G SYRGT+ST  +G  C  W+S      P+S  R        G   NYCRNPD  
Sbjct: 127 CYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLGN-HNYCRNPDRD 185

Query: 768 AAPYCYTRDPG-VRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQEC 826
           + P+CY    G    E+C+   CS+                              G  +C
Sbjct: 186 SKPWCYVFKAGKYSSEFCSTPACSE------------------------------GNSDC 215

Query: 827 YHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLI----MNYCRNPDPVA 882
           Y GNG +YRGT+S T +G +C  W+SM       T +  P+A  +     NYCRNPD  A
Sbjct: 216 YFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQ-NPSAQALGLGKHNYCRNPDGDA 274

Query: 883 APYCYT-RDPSVRWEYCNLTQCS 904
            P+C+  ++  + WEYC++  CS
Sbjct: 275 KPWCHVLKNRRLTWEYCDVPSCS 297



 Score =  110 bits (274), Expect = 2e-23
 Identities = 71/203 (34%), Positives = 95/203 (46%), Gaps = 42/203 (20%)

Query: 826  CYHGNGQSYRGTYSTTVTGRTCQAWSSMT----PHSHSRTPEYYPNAGLIMNYCRNPDPV 881
            CY   G SYRGT+ST  +G  C  W+S      P+S  R        G   NYCRNPD  
Sbjct: 127  CYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLGN-HNYCRNPDRD 185

Query: 882  AAPYCYT-RDPSVRWEYCNLTQCSDAEGTAVAPPTITPIPSLEAPSEQAPTEQRPGVQEC 940
            + P+CY  +      E+C+   CS+                              G  +C
Sbjct: 186  SKPWCYVFKAGKYSSEFCSTPACSE------------------------------GNSDC 215

Query: 941  YHGNGQSYQGTYFITVTGRTCQAWSSMTPHSHSRTPAYYPNA---GLIK-NYCRNPDPVA 996
            Y GNG +Y+GT+ +T +G +C  W+SM       T A  P+A   GL K NYCRNPD  A
Sbjct: 216  YFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYT-AQNPSAQALGLGKHNYCRNPDGDA 274

Query: 997  APWCYT-TDPSVRWEYCNLTRCS 1018
             PWC+   +  + WEYC++  CS
Sbjct: 275  KPWCHVLKNRRLTWEYCDVPSCS 297



 Score =  109 bits (273), Expect = 2e-23
 Identities = 66/201 (32%), Positives = 93/201 (46%), Gaps = 40/201 (19%)

Query: 1274 CYHGDGQSYRGSFSTTVTGRTCQSWSSMT---PHWHQRTTEYYPNGGLTRNYCRNPDAEI 1330
            CY   G SYRG++ST  +G  C +W+S       +  R  +    G    NYCRNPD + 
Sbjct: 127  CYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLGNHNYCRNPDRDS 186

Query: 1331 RPWCYTMDPS-VRWEYCNLTQCPVMESTLLTTPTVVPVPSTELPSEEAPTENSTGVQDCY 1389
            +PWCY         E+C+   C                              S G  DCY
Sbjct: 187  KPWCYVFKAGKYSSEFCSTPAC------------------------------SEGNSDCY 216

Query: 1390 RGDGQSYRGTLSTTITGRTCQSWSSMTPHWHRRIPLYYPNA---GLTR-NYCRNPDAEIR 1445
             G+G +YRGT S T +G +C  W+SM     +      P+A   GL + NYCRNPD + +
Sbjct: 217  FGNGSAYRGTHSLTESGASCLPWNSMI-LIGKVYTAQNPSAQALGLGKHNYCRNPDGDAK 275

Query: 1446 PWCYTM-DPSVRWEYCNLTRC 1465
            PWC+ + +  + WEYC++  C
Sbjct: 276  PWCHVLKNRRLTWEYCDVPSC 296



 Score =  108 bits (271), Expect = 4e-23
 Identities = 68/203 (33%), Positives = 93/203 (45%), Gaps = 42/203 (20%)

Query: 28  CYHGDGQSYRGTYSTTVTGRTCQAWSSMT----PHQHNRTTENYPNAGLIMNYCRNPDAV 83
           CY   G SYRGT+ST  +G  C  W+S      P+   R        G   NYCRNPD  
Sbjct: 127 CYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLGN-HNYCRNPDRD 185

Query: 84  AAPYCYTRDPG-VRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQEC 142
           + P+CY    G    E+C+   CS+                              G  +C
Sbjct: 186 SKPWCYVFKAGKYSSEFCSTPACSE------------------------------GNSDC 215

Query: 143 YHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLI----MNYCRNPDAVA 198
           Y GNG +YRGT+S T +G +C  W+SM       T +  P+A  +     NYCRNPD  A
Sbjct: 216 YFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQ-NPSAQALGLGKHNYCRNPDGDA 274

Query: 199 APYCYT-RDPGVRWEYCNLTQCS 220
            P+C+  ++  + WEYC++  CS
Sbjct: 275 KPWCHVLKNRRLTWEYCDVPSCS 297



 Score = 74.3 bits (181), Expect = 1e-12
 Identities = 38/95 (40%), Positives = 55/95 (57%), Gaps = 6/95 (6%)

Query: 17  AAPEQSHVVQDCYHGDGQSYRGTYSTTVTGRTCQAWSSMTPHQHNRTTENYPNAGLI--- 73
           + P  S    DCY G+G +YRGT+S T +G +C  W+SM       T +N P+A  +   
Sbjct: 204 STPACSEGNSDCYFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQN-PSAQALGLG 262

Query: 74  -MNYCRNPDAVAAPYCYT-RDPGVRWEYCNLTQCS 106
             NYCRNPD  A P+C+  ++  + WEYC++  CS
Sbjct: 263 KHNYCRNPDGDAKPWCHVLKNRRLTWEYCDVPSCS 297


>gi|14702169 plasminogen activator, tissue isoform 3 preproprotein
            [Homo sapiens]
          Length = 516

 Score =  236 bits (602), Expect = 2e-61
 Identities = 163/475 (34%), Positives = 217/475 (45%), Gaps = 92/475 (19%)

Query: 1616 CYHGNGQSYRGTFSTTVTGRTCQSWSSMT----PHRHQRTPENYPNDGLTMNYCRNPDAD 1671
            CY   G SYRGT+ST  +G  C +W+S      P+  +R P+         NYCRNPD D
Sbjct: 81   CYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRR-PDAIRLGLGNHNYCRNPDRD 139

Query: 1672 TGPWCFTMDPS-IRWEYCNLTRCSDTEGTVVAPPTVIQVPSLGPPSEQDCMFGNGKGYRG 1730
            + PWC+         E+C+   CS+                       DC FGNG  YRG
Sbjct: 140  SKPWCYVFKAGKYSSEFCSTPACSE--------------------GNSDCYFGNGSAYRG 179

Query: 1731 KKATTVTGTPCQEW----------AAQEPHRHSTFIPGTNKWAGLEK-NYCRNPDGDING 1779
              + T +G  C  W           AQ P   +          GL K NYCRNPDGD   
Sbjct: 180  THSLTESGASCLPWNSMILIGKVYTAQNPSAQAL---------GLGKHNYCRNPDGDAK- 229

Query: 1780 PWCYTMNPRKL-FDYCDIPLCASSSFDCGKPQVEPKKCPGSIVGGCVAHPHSWPWQVSLR 1838
            PWC+ +  R+L ++YCD+P C++    CG  Q    +    I GG  A   S PWQ ++ 
Sbjct: 230  PWCHVLKNRRLTWEYCDVPSCST----CGLRQYSQPQF--RIKGGLFADIASHPWQAAI- 282

Query: 1839 TRFGKH--------FCGGTLISPEWVLTAAHCLKKSSRPSSYKVILGAHQEVNLESHVQE 1890
              F KH         CGG LIS  W+L+AAHC ++   P    VILG    V      Q+
Sbjct: 283  --FAKHRRSPGERFLCGGILISSCWILSAAHCFQERFPPHHLTVILGRTYRVVPGEEEQK 340

Query: 1891 IEVSRLFL------EPTQADIALLKL----SRPAVITDKVMPACLPSPDYMVTARTECYI 1940
             EV +  +      +    DIALL+L    SR A  +  V   CLP  D  +   TEC +
Sbjct: 341  FEVEKYIVHKEFDDDTYDNDIALLQLKSDSSRCAQESSVVRTVCLPPADLQLPDWTECEL 400

Query: 1941 TGWG--ETQGTFGTGLLKEAQLLVIENEVCNHY---------KYICAEHLARGT------ 1983
            +G+G  E    F +  LKEA + +  +  C              +CA     G       
Sbjct: 401  SGYGKHEALSPFYSERLKEAHVRLYPSSRCTSQHLLNRTVTDNMLCAGDTRSGGPQANLH 460

Query: 1984 DSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYARVSRFVTWIEGMMR 2038
            D+CQGDSGGPLVC    +  L G+ SWGLGC + + PGVY +V+ ++ WI   MR
Sbjct: 461  DACQGDSGGPLVCLNDGRMTLVGIISWGLGCGQKDVPGVYTKVTNYLDWIRDNMR 515



 Score =  113 bits (282), Expect = 2e-24
 Identities = 71/203 (34%), Positives = 92/203 (45%), Gaps = 42/203 (20%)

Query: 1388 CYRGDGQSYRGTLSTTITGRTCQSWSSMT----PHWHRRIPLYYPNAGLTRNYCRNPDAE 1443
            CY   G SYRGT ST  +G  C +W+S      P+  RR        G   NYCRNPD +
Sbjct: 81   CYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLG-NHNYCRNPDRD 139

Query: 1444 IRPWCYTMDPS-VRWEYCNLTRCPVTESSVLTTPTVAPVPSTEAPSEQAPPEKSPVVQDC 1502
             +PWCY         E+C+   C    S                              DC
Sbjct: 140  SKPWCYVFKAGKYSSEFCSTPACSEGNS------------------------------DC 169

Query: 1503 YHGDGRSYRGISSTTVTGRTCQSWSSMIPHWHQRTPENYPNA---GL-TENYCRNPDSGK 1558
            Y G+G +YRG  S T +G +C  W+SMI      T +N P+A   GL   NYCRNPD   
Sbjct: 170  YFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQN-PSAQALGLGKHNYCRNPDGDA 228

Query: 1559 QPWCYT-TDPCVRWEYCNLTQCS 1580
            +PWC+   +  + WEYC++  CS
Sbjct: 229  KPWCHVLKNRRLTWEYCDVPSCS 251



 Score =  113 bits (282), Expect = 2e-24
 Identities = 65/200 (32%), Positives = 87/200 (43%), Gaps = 38/200 (19%)

Query: 1054 CYYHYGQSYRGTYSTTVTGRTCQAWSSMTPHQH---SRTPENYPNAGLTRNYCRNPDAEI 1110
            CY   G SYRGT+ST  +G  C  W+S    Q     R P+         NYCRNPD + 
Sbjct: 81   CYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLGNHNYCRNPDRDS 140

Query: 1111 RPWCYTMDPS-VRWEYCNLTQCLVTESSVLATLTVVPDPSTEASSEEAPTEQSPGVQDCY 1169
            +PWCY         E+C+   C                              S G  DCY
Sbjct: 141  KPWCYVFKAGKYSSEFCSTPAC------------------------------SEGNSDCY 170

Query: 1170 HGDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGL---TRNYCRNPDAEISP 1226
             G+G +YRG+ S T +G +C  W+SM       T +      L     NYCRNPD +  P
Sbjct: 171  FGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQNPSAQALGLGKHNYCRNPDGDAKP 230

Query: 1227 WCYTM-DPNVRWEYCNLTQC 1245
            WC+ + +  + WEYC++  C
Sbjct: 231  WCHVLKNRRLTWEYCDVPSC 250



 Score =  111 bits (278), Expect = 6e-24
 Identities = 68/202 (33%), Positives = 94/202 (46%), Gaps = 42/202 (20%)

Query: 940  CYHGNGQSYQGTYFITVTGRTCQAWSSMT----PHSHSRTPAYYPNAGLIKNYCRNPDPV 995
            CY   G SY+GT+    +G  C  W+S      P+S  R  A     G   NYCRNPD  
Sbjct: 81   CYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLGN-HNYCRNPDRD 139

Query: 996  AAPWCYTTDPS-VRWEYCNLTRCSDAEWTAFVPPNVILAPSLEAFFEQALTEETPGVQDC 1054
            + PWCY         E+C+   CS+                              G  DC
Sbjct: 140  SKPWCYVFKAGKYSSEFCSTPACSE------------------------------GNSDC 169

Query: 1055 YYHYGQSYRGTYSTTVTGRTCQAWSSMTPHQHSRTPENYPNA---GLTR-NYCRNPDAEI 1110
            Y+  G +YRGT+S T +G +C  W+SM       T +N P+A   GL + NYCRNPD + 
Sbjct: 170  YFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQN-PSAQALGLGKHNYCRNPDGDA 228

Query: 1111 RPWCYTM-DPSVRWEYCNLTQC 1131
            +PWC+ + +  + WEYC++  C
Sbjct: 229  KPWCHVLKNRRLTWEYCDVPSC 250



 Score =  111 bits (278), Expect = 6e-24
 Identities = 62/192 (32%), Positives = 87/192 (45%), Gaps = 30/192 (15%)

Query: 1168 CYHGDGQSYRGSFSTTVTGRTCQSWSSMT---PHWHQRTTEYYPNGGLTRNYCRNPDAEI 1224
            CY   G SYRG++ST  +G  C +W+S       +  R  +    G    NYCRNPD + 
Sbjct: 81   CYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLGNHNYCRNPDRDS 140

Query: 1225 SPWCYTMDPN-VRWEYCNLTQCPVTESSVLATSTAVSEQAPTEQSPTVQDCYHGDGQSYR 1283
             PWCY         E+C+   C    S                      DCY G+G +YR
Sbjct: 141  KPWCYVFKAGKYSSEFCSTPACSEGNS----------------------DCYFGNGSAYR 178

Query: 1284 GSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGL---TRNYCRNPDAEIRPWCYTM-DP 1339
            G+ S T +G +C  W+SM       T +      L     NYCRNPD + +PWC+ + + 
Sbjct: 179  GTHSLTESGASCLPWNSMILIGKVYTAQNPSAQALGLGKHNYCRNPDGDAKPWCHVLKNR 238

Query: 1340 SVRWEYCNLTQC 1351
             + WEYC++  C
Sbjct: 239  RLTWEYCDVPSC 250



 Score =  110 bits (276), Expect = 1e-23
 Identities = 69/203 (33%), Positives = 94/203 (46%), Gaps = 42/203 (20%)

Query: 142 CYHGNGQSYRGTYSTTVTGRTCQAWSSMT----PHSHSRTPEYYPNAGLIMNYCRNPDAV 197
           CY   G SYRGT+ST  +G  C  W+S      P+S  R        G   NYCRNPD  
Sbjct: 81  CYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLGN-HNYCRNPDRD 139

Query: 198 AAPYCYTRDPG-VRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQEC 256
           + P+CY    G    E+C+   CS+                              G  +C
Sbjct: 140 SKPWCYVFKAGKYSSEFCSTPACSE------------------------------GNSDC 169

Query: 257 YHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLI----MNYCRNPDAVA 312
           Y GNG +YRGT+S T +G +C  W+SM       T +  P+A  +     NYCRNPD  A
Sbjct: 170 YFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQ-NPSAQALGLGKHNYCRNPDGDA 228

Query: 313 APYCYT-RDPGVRWEYCNLTQCS 334
            P+C+  ++  + WEYC++  CS
Sbjct: 229 KPWCHVLKNRRLTWEYCDVPSCS 251



 Score =  110 bits (276), Expect = 1e-23
 Identities = 69/203 (33%), Positives = 94/203 (46%), Gaps = 42/203 (20%)

Query: 256 CYHGNGQSYRGTYSTTVTGRTCQAWSSMT----PHSHSRTPEYYPNAGLIMNYCRNPDAV 311
           CY   G SYRGT+ST  +G  C  W+S      P+S  R        G   NYCRNPD  
Sbjct: 81  CYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLGN-HNYCRNPDRD 139

Query: 312 AAPYCYTRDPG-VRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQEC 370
           + P+CY    G    E+C+   CS+                              G  +C
Sbjct: 140 SKPWCYVFKAGKYSSEFCSTPACSE------------------------------GNSDC 169

Query: 371 YHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLI----MNYCRNPDAVA 426
           Y GNG +YRGT+S T +G +C  W+SM       T +  P+A  +     NYCRNPD  A
Sbjct: 170 YFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQ-NPSAQALGLGKHNYCRNPDGDA 228

Query: 427 APYCYT-RDPGVRWEYCNLTQCS 448
            P+C+  ++  + WEYC++  CS
Sbjct: 229 KPWCHVLKNRRLTWEYCDVPSCS 251



 Score =  110 bits (276), Expect = 1e-23
 Identities = 69/203 (33%), Positives = 94/203 (46%), Gaps = 42/203 (20%)

Query: 370 CYHGNGQSYRGTYSTTVTGRTCQAWSSMT----PHSHSRTPEYYPNAGLIMNYCRNPDAV 425
           CY   G SYRGT+ST  +G  C  W+S      P+S  R        G   NYCRNPD  
Sbjct: 81  CYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLGN-HNYCRNPDRD 139

Query: 426 AAPYCYTRDPG-VRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQEC 484
           + P+CY    G    E+C+   CS+                              G  +C
Sbjct: 140 SKPWCYVFKAGKYSSEFCSTPACSE------------------------------GNSDC 169

Query: 485 YHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLI----MNYCRNPDAVA 540
           Y GNG +YRGT+S T +G +C  W+SM       T +  P+A  +     NYCRNPD  A
Sbjct: 170 YFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQ-NPSAQALGLGKHNYCRNPDGDA 228

Query: 541 APYCYT-RDPGVRWEYCNLTQCS 562
            P+C+  ++  + WEYC++  CS
Sbjct: 229 KPWCHVLKNRRLTWEYCDVPSCS 251



 Score =  110 bits (276), Expect = 1e-23
 Identities = 69/203 (33%), Positives = 94/203 (46%), Gaps = 42/203 (20%)

Query: 484 CYHGNGQSYRGTYSTTVTGRTCQAWSSMT----PHSHSRTPEYYPNAGLIMNYCRNPDAV 539
           CY   G SYRGT+ST  +G  C  W+S      P+S  R        G   NYCRNPD  
Sbjct: 81  CYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLGN-HNYCRNPDRD 139

Query: 540 AAPYCYTRDPG-VRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQEC 598
           + P+CY    G    E+C+   CS+                              G  +C
Sbjct: 140 SKPWCYVFKAGKYSSEFCSTPACSE------------------------------GNSDC 169

Query: 599 YHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLI----MNYCRNPDAVA 654
           Y GNG +YRGT+S T +G +C  W+SM       T +  P+A  +     NYCRNPD  A
Sbjct: 170 YFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQ-NPSAQALGLGKHNYCRNPDGDA 228

Query: 655 APYCYT-RDPGVRWEYCNLTQCS 676
            P+C+  ++  + WEYC++  CS
Sbjct: 229 KPWCHVLKNRRLTWEYCDVPSCS 251



 Score =  110 bits (276), Expect = 1e-23
 Identities = 69/203 (33%), Positives = 94/203 (46%), Gaps = 42/203 (20%)

Query: 598 CYHGNGQSYRGTYSTTVTGRTCQAWSSMT----PHSHSRTPEYYPNAGLIMNYCRNPDAV 653
           CY   G SYRGT+ST  +G  C  W+S      P+S  R        G   NYCRNPD  
Sbjct: 81  CYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLGN-HNYCRNPDRD 139

Query: 654 AAPYCYTRDPG-VRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQEC 712
           + P+CY    G    E+C+   CS+                              G  +C
Sbjct: 140 SKPWCYVFKAGKYSSEFCSTPACSE------------------------------GNSDC 169

Query: 713 YHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLI----MNYCRNPDAVA 768
           Y GNG +YRGT+S T +G +C  W+SM       T +  P+A  +     NYCRNPD  A
Sbjct: 170 YFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQ-NPSAQALGLGKHNYCRNPDGDA 228

Query: 769 APYCYT-RDPGVRWEYCNLTQCS 790
            P+C+  ++  + WEYC++  CS
Sbjct: 229 KPWCHVLKNRRLTWEYCDVPSCS 251



 Score =  110 bits (275), Expect = 1e-23
 Identities = 69/203 (33%), Positives = 94/203 (46%), Gaps = 42/203 (20%)

Query: 712 CYHGNGQSYRGTYSTTVTGRTCQAWSSMT----PHSHSRTPEYYPNAGLIMNYCRNPDAV 767
           CY   G SYRGT+ST  +G  C  W+S      P+S  R        G   NYCRNPD  
Sbjct: 81  CYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLGN-HNYCRNPDRD 139

Query: 768 AAPYCYTRDPG-VRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQEC 826
           + P+CY    G    E+C+   CS+                              G  +C
Sbjct: 140 SKPWCYVFKAGKYSSEFCSTPACSE------------------------------GNSDC 169

Query: 827 YHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLI----MNYCRNPDPVA 882
           Y GNG +YRGT+S T +G +C  W+SM       T +  P+A  +     NYCRNPD  A
Sbjct: 170 YFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQ-NPSAQALGLGKHNYCRNPDGDA 228

Query: 883 APYCYT-RDPSVRWEYCNLTQCS 904
            P+C+  ++  + WEYC++  CS
Sbjct: 229 KPWCHVLKNRRLTWEYCDVPSCS 251



 Score =  110 bits (274), Expect = 2e-23
 Identities = 71/203 (34%), Positives = 95/203 (46%), Gaps = 42/203 (20%)

Query: 826  CYHGNGQSYRGTYSTTVTGRTCQAWSSMT----PHSHSRTPEYYPNAGLIMNYCRNPDPV 881
            CY   G SYRGT+ST  +G  C  W+S      P+S  R        G   NYCRNPD  
Sbjct: 81   CYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLGN-HNYCRNPDRD 139

Query: 882  AAPYCYT-RDPSVRWEYCNLTQCSDAEGTAVAPPTITPIPSLEAPSEQAPTEQRPGVQEC 940
            + P+CY  +      E+C+   CS+                              G  +C
Sbjct: 140  SKPWCYVFKAGKYSSEFCSTPACSE------------------------------GNSDC 169

Query: 941  YHGNGQSYQGTYFITVTGRTCQAWSSMTPHSHSRTPAYYPNA---GLIK-NYCRNPDPVA 996
            Y GNG +Y+GT+ +T +G +C  W+SM       T A  P+A   GL K NYCRNPD  A
Sbjct: 170  YFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYT-AQNPSAQALGLGKHNYCRNPDGDA 228

Query: 997  APWCYT-TDPSVRWEYCNLTRCS 1018
             PWC+   +  + WEYC++  CS
Sbjct: 229  KPWCHVLKNRRLTWEYCDVPSCS 251



 Score =  109 bits (273), Expect = 2e-23
 Identities = 66/201 (32%), Positives = 93/201 (46%), Gaps = 40/201 (19%)

Query: 1274 CYHGDGQSYRGSFSTTVTGRTCQSWSSMT---PHWHQRTTEYYPNGGLTRNYCRNPDAEI 1330
            CY   G SYRG++ST  +G  C +W+S       +  R  +    G    NYCRNPD + 
Sbjct: 81   CYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLGNHNYCRNPDRDS 140

Query: 1331 RPWCYTMDPS-VRWEYCNLTQCPVMESTLLTTPTVVPVPSTELPSEEAPTENSTGVQDCY 1389
            +PWCY         E+C+   C                              S G  DCY
Sbjct: 141  KPWCYVFKAGKYSSEFCSTPAC------------------------------SEGNSDCY 170

Query: 1390 RGDGQSYRGTLSTTITGRTCQSWSSMTPHWHRRIPLYYPNA---GLTR-NYCRNPDAEIR 1445
             G+G +YRGT S T +G +C  W+SM     +      P+A   GL + NYCRNPD + +
Sbjct: 171  FGNGSAYRGTHSLTESGASCLPWNSMI-LIGKVYTAQNPSAQALGLGKHNYCRNPDGDAK 229

Query: 1446 PWCYTM-DPSVRWEYCNLTRC 1465
            PWC+ + +  + WEYC++  C
Sbjct: 230  PWCHVLKNRRLTWEYCDVPSC 250



 Score =  108 bits (271), Expect = 4e-23
 Identities = 68/203 (33%), Positives = 93/203 (45%), Gaps = 42/203 (20%)

Query: 28  CYHGDGQSYRGTYSTTVTGRTCQAWSSMT----PHQHNRTTENYPNAGLIMNYCRNPDAV 83
           CY   G SYRGT+ST  +G  C  W+S      P+   R        G   NYCRNPD  
Sbjct: 81  CYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLGN-HNYCRNPDRD 139

Query: 84  AAPYCYTRDPG-VRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQEC 142
           + P+CY    G    E+C+   CS+                              G  +C
Sbjct: 140 SKPWCYVFKAGKYSSEFCSTPACSE------------------------------GNSDC 169

Query: 143 YHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLI----MNYCRNPDAVA 198
           Y GNG +YRGT+S T +G +C  W+SM       T +  P+A  +     NYCRNPD  A
Sbjct: 170 YFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQ-NPSAQALGLGKHNYCRNPDGDA 228

Query: 199 APYCYT-RDPGVRWEYCNLTQCS 220
            P+C+  ++  + WEYC++  CS
Sbjct: 229 KPWCHVLKNRRLTWEYCDVPSCS 251



 Score = 74.3 bits (181), Expect = 1e-12
 Identities = 38/95 (40%), Positives = 55/95 (57%), Gaps = 6/95 (6%)

Query: 17  AAPEQSHVVQDCYHGDGQSYRGTYSTTVTGRTCQAWSSMTPHQHNRTTENYPNAGLI--- 73
           + P  S    DCY G+G +YRGT+S T +G +C  W+SM       T +N P+A  +   
Sbjct: 158 STPACSEGNSDCYFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQN-PSAQALGLG 216

Query: 74  -MNYCRNPDAVAAPYCYT-RDPGVRWEYCNLTQCS 106
             NYCRNPD  A P+C+  ++  + WEYC++  CS
Sbjct: 217 KHNYCRNPDGDAKPWCHVLKNRRLTWEYCDVPSCS 251


>gi|22035663 lipoprotein, Lp(a)-like 2 precursor [Homo sapiens]
          Length = 132

 Score =  210 bits (534), Expect = 1e-53
 Identities = 97/125 (77%), Positives = 102/125 (81%)

Query: 1   MEHKEVVLLLLLFLKSAAPEQSHVVQDCYHGDGQSYRGTYSTTVTGRTCQAWSSMTPHQH 60
           MEHKEVVLLLLLFLKSA  E    VQ+CYH +GQSYRGTY TTVTGRTCQAWSSMTPHQH
Sbjct: 1   MEHKEVVLLLLLFLKSAPTETGPSVQECYHSNGQSYRGTYFTTVTGRTCQAWSSMTPHQH 60

Query: 61  NRTTENYPNAGLIMNYCRNPDAVAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTP 120
           +RT E YPN GLI NYCRNPD  A P+CYT DP VRWEYCNLT+CSD EGT   P TV P
Sbjct: 61  SRTPEKYPNDGLISNYCRNPDCSAGPWCYTTDPNVRWEYCNLTRCSDDEGTVFVPLTVIP 120

Query: 121 VPSLE 125
           VPSLE
Sbjct: 121 VPSLE 125



 Score =  196 bits (498), Expect = 2e-49
 Identities = 89/116 (76%), Positives = 92/116 (79%)

Query: 927  EQAPTEQRPGVQECYHGNGQSYQGTYFITVTGRTCQAWSSMTPHSHSRTPAYYPNAGLIK 986
            + APTE  P VQECYH NGQSY+GTYF TVTGRTCQAWSSMTPH HSRTP  YPN GLI 
Sbjct: 15   KSAPTETGPSVQECYHSNGQSYRGTYFTTVTGRTCQAWSSMTPHQHSRTPEKYPNDGLIS 74

Query: 987  NYCRNPDPVAAPWCYTTDPSVRWEYCNLTRCSDAEWTAFVPPNVILAPSLEAFFEQ 1042
            NYCRNPD  A PWCYTTDP+VRWEYCNLTRCSD E T FVP  VI  PSLE  F Q
Sbjct: 75   NYCRNPDCSAGPWCYTTDPNVRWEYCNLTRCSDDEGTVFVPLTVIPVPSLEDSFIQ 130



 Score =  195 bits (495), Expect = 4e-49
 Identities = 87/111 (78%), Positives = 90/111 (81%)

Query: 129 EQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIM 188
           + APTE  P VQECYH NGQSYRGTY TTVTGRTCQAWSSMTPH HSRTPE YPN GLI 
Sbjct: 15  KSAPTETGPSVQECYHSNGQSYRGTYFTTVTGRTCQAWSSMTPHQHSRTPEKYPNDGLIS 74

Query: 189 NYCRNPDAVAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLE 239
           NYCRNPD  A P+CYT DP VRWEYCNLT+CSD EGT   P TV PVPSLE
Sbjct: 75  NYCRNPDCSAGPWCYTTDPNVRWEYCNLTRCSDDEGTVFVPLTVIPVPSLE 125



 Score =  195 bits (495), Expect = 4e-49
 Identities = 87/111 (78%), Positives = 90/111 (81%)

Query: 243 EQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIM 302
           + APTE  P VQECYH NGQSYRGTY TTVTGRTCQAWSSMTPH HSRTPE YPN GLI 
Sbjct: 15  KSAPTETGPSVQECYHSNGQSYRGTYFTTVTGRTCQAWSSMTPHQHSRTPEKYPNDGLIS 74

Query: 303 NYCRNPDAVAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLE 353
           NYCRNPD  A P+CYT DP VRWEYCNLT+CSD EGT   P TV PVPSLE
Sbjct: 75  NYCRNPDCSAGPWCYTTDPNVRWEYCNLTRCSDDEGTVFVPLTVIPVPSLE 125



 Score =  195 bits (495), Expect = 4e-49
 Identities = 87/111 (78%), Positives = 90/111 (81%)

Query: 357 EQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIM 416
           + APTE  P VQECYH NGQSYRGTY TTVTGRTCQAWSSMTPH HSRTPE YPN GLI 
Sbjct: 15  KSAPTETGPSVQECYHSNGQSYRGTYFTTVTGRTCQAWSSMTPHQHSRTPEKYPNDGLIS 74

Query: 417 NYCRNPDAVAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLE 467
           NYCRNPD  A P+CYT DP VRWEYCNLT+CSD EGT   P TV PVPSLE
Sbjct: 75  NYCRNPDCSAGPWCYTTDPNVRWEYCNLTRCSDDEGTVFVPLTVIPVPSLE 125



 Score =  195 bits (495), Expect = 4e-49
 Identities = 87/111 (78%), Positives = 90/111 (81%)

Query: 471 EQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIM 530
           + APTE  P VQECYH NGQSYRGTY TTVTGRTCQAWSSMTPH HSRTPE YPN GLI 
Sbjct: 15  KSAPTETGPSVQECYHSNGQSYRGTYFTTVTGRTCQAWSSMTPHQHSRTPEKYPNDGLIS 74

Query: 531 NYCRNPDAVAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLE 581
           NYCRNPD  A P+CYT DP VRWEYCNLT+CSD EGT   P TV PVPSLE
Sbjct: 75  NYCRNPDCSAGPWCYTTDPNVRWEYCNLTRCSDDEGTVFVPLTVIPVPSLE 125



 Score =  195 bits (495), Expect = 4e-49
 Identities = 87/111 (78%), Positives = 90/111 (81%)

Query: 585 EQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIM 644
           + APTE  P VQECYH NGQSYRGTY TTVTGRTCQAWSSMTPH HSRTPE YPN GLI 
Sbjct: 15  KSAPTETGPSVQECYHSNGQSYRGTYFTTVTGRTCQAWSSMTPHQHSRTPEKYPNDGLIS 74

Query: 645 NYCRNPDAVAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLE 695
           NYCRNPD  A P+CYT DP VRWEYCNLT+CSD EGT   P TV PVPSLE
Sbjct: 75  NYCRNPDCSAGPWCYTTDPNVRWEYCNLTRCSDDEGTVFVPLTVIPVPSLE 125



 Score =  195 bits (495), Expect = 4e-49
 Identities = 87/111 (78%), Positives = 90/111 (81%)

Query: 699 EQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIM 758
           + APTE  P VQECYH NGQSYRGTY TTVTGRTCQAWSSMTPH HSRTPE YPN GLI 
Sbjct: 15  KSAPTETGPSVQECYHSNGQSYRGTYFTTVTGRTCQAWSSMTPHQHSRTPEKYPNDGLIS 74

Query: 759 NYCRNPDAVAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLE 809
           NYCRNPD  A P+CYT DP VRWEYCNLT+CSD EGT   P TV PVPSLE
Sbjct: 75  NYCRNPDCSAGPWCYTTDPNVRWEYCNLTRCSDDEGTVFVPLTVIPVPSLE 125



 Score =  194 bits (492), Expect = 1e-48
 Identities = 82/110 (74%), Positives = 92/110 (83%)

Query: 1603 EAAPTEQTPVVRQCYHGNGQSYRGTFSTTVTGRTCQSWSSMTPHRHQRTPENYPNDGLTM 1662
            ++APTE  P V++CYH NGQSYRGT+ TTVTGRTCQ+WSSMTPH+H RTPE YPNDGL  
Sbjct: 15   KSAPTETGPSVQECYHSNGQSYRGTYFTTVTGRTCQAWSSMTPHQHSRTPEKYPNDGLIS 74

Query: 1663 NYCRNPDADTGPWCFTMDPSIRWEYCNLTRCSDTEGTVVAPPTVIQVPSL 1712
            NYCRNPD   GPWC+T DP++RWEYCNLTRCSD EGTV  P TVI VPSL
Sbjct: 75   NYCRNPDCSAGPWCYTTDPNVRWEYCNLTRCSDDEGTVFVPLTVIPVPSL 124



 Score =  193 bits (491), Expect = 1e-48
 Identities = 85/111 (76%), Positives = 91/111 (81%)

Query: 813 EQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIM 872
           + APTE  P VQECYH NGQSYRGTY TTVTGRTCQAWSSMTPH HSRTPE YPN GLI 
Sbjct: 15  KSAPTETGPSVQECYHSNGQSYRGTYFTTVTGRTCQAWSSMTPHQHSRTPEKYPNDGLIS 74

Query: 873 NYCRNPDPVAAPYCYTRDPSVRWEYCNLTQCSDAEGTAVAPPTITPIPSLE 923
           NYCRNPD  A P+CYT DP+VRWEYCNLT+CSD EGT   P T+ P+PSLE
Sbjct: 75  NYCRNPDCSAGPWCYTTDPNVRWEYCNLTRCSDDEGTVFVPLTVIPVPSLE 125



 Score =  179 bits (454), Expect = 2e-44
 Identities = 80/115 (69%), Positives = 87/115 (75%)

Query: 1039 FFEQALTEETPGVQDCYYHYGQSYRGTYSTTVTGRTCQAWSSMTPHQHSRTPENYPNAGL 1098
            F + A TE  P VQ+CY+  GQSYRGTY TTVTGRTCQAWSSMTPHQHSRTPE YPN GL
Sbjct: 13   FLKSAPTETGPSVQECYHSNGQSYRGTYFTTVTGRTCQAWSSMTPHQHSRTPEKYPNDGL 72

Query: 1099 TRNYCRNPDAEIRPWCYTMDPSVRWEYCNLTQCLVTESSVLATLTVVPDPSTEAS 1153
              NYCRNPD    PWCYT DP+VRWEYCNLT+C   E +V   LTV+P PS E S
Sbjct: 73   ISNYCRNPDCSAGPWCYTTDPNVRWEYCNLTRCSDDEGTVFVPLTVIPVPSLEDS 127



 Score =  173 bits (438), Expect = 2e-42
 Identities = 74/111 (66%), Positives = 85/111 (76%)

Query: 1261 EQAPTEQSPTVQDCYHGDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTR 1320
            + APTE  P+VQ+CYH +GQSYRG++ TTVTGRTCQ+WSSMTPH H RT E YPN GL  
Sbjct: 15   KSAPTETGPSVQECYHSNGQSYRGTYFTTVTGRTCQAWSSMTPHQHSRTPEKYPNDGLIS 74

Query: 1321 NYCRNPDAEIRPWCYTMDPSVRWEYCNLTQCPVMESTLLTTPTVVPVPSTE 1371
            NYCRNPD    PWCYT DP+VRWEYCNLT+C   E T+    TV+PVPS E
Sbjct: 75   NYCRNPDCSAGPWCYTTDPNVRWEYCNLTRCSDDEGTVFVPLTVIPVPSLE 125



 Score =  171 bits (432), Expect = 9e-42
 Identities = 74/111 (66%), Positives = 83/111 (74%)

Query: 1489 EQAPPEKSPVVQDCYHGDGRSYRGISSTTVTGRTCQSWSSMIPHWHQRTPENYPNAGLTE 1548
            + AP E  P VQ+CYH +G+SYRG   TTVTGRTCQ+WSSM PH H RTPE YPN GL  
Sbjct: 15   KSAPTETGPSVQECYHSNGQSYRGTYFTTVTGRTCQAWSSMTPHQHSRTPEKYPNDGLIS 74

Query: 1549 NYCRNPDSGKQPWCYTTDPCVRWEYCNLTQCSETESGVLETPTVVPVPSME 1599
            NYCRNPD    PWCYTTDP VRWEYCNLT+CS+ E  V    TV+PVPS+E
Sbjct: 75   NYCRNPDCSAGPWCYTTDPNVRWEYCNLTRCSDDEGTVFVPLTVIPVPSLE 125



 Score =  164 bits (416), Expect = 6e-40
 Identities = 69/105 (65%), Positives = 78/105 (74%)

Query: 1155 EEAPTEQSPGVQDCYHGDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTR 1214
            + APTE  P VQ+CYH +GQSYRG++ TTVTGRTCQ+WSSMTPH H RT E YPN GL  
Sbjct: 15   KSAPTETGPSVQECYHSNGQSYRGTYFTTVTGRTCQAWSSMTPHQHSRTPEKYPNDGLIS 74

Query: 1215 NYCRNPDAEISPWCYTMDPNVRWEYCNLTQCPVTESSVLATSTAV 1259
            NYCRNPD    PWCYT DPNVRWEYCNLT+C   E +V    T +
Sbjct: 75   NYCRNPDCSAGPWCYTTDPNVRWEYCNLTRCSDDEGTVFVPLTVI 119



 Score =  164 bits (414), Expect = 1e-39
 Identities = 72/111 (64%), Positives = 79/111 (71%)

Query: 1375 EEAPTENSTGVQDCYRGDGQSYRGTLSTTITGRTCQSWSSMTPHWHRRIPLYYPNAGLTR 1434
            + APTE    VQ+CY  +GQSYRGT  TT+TGRTCQ+WSSMTPH H R P  YPN GL  
Sbjct: 15   KSAPTETGPSVQECYHSNGQSYRGTYFTTVTGRTCQAWSSMTPHQHSRTPEKYPNDGLIS 74

Query: 1435 NYCRNPDAEIRPWCYTMDPSVRWEYCNLTRCPVTESSVLTTPTVAPVPSTE 1485
            NYCRNPD    PWCYT DP+VRWEYCNLTRC   E +V    TV PVPS E
Sbjct: 75   NYCRNPDCSAGPWCYTTDPNVRWEYCNLTRCSDDEGTVFVPLTVIPVPSLE 125



 Score = 89.7 bits (221), Expect = 3e-17
 Identities = 42/91 (46%), Positives = 54/91 (59%), Gaps = 2/91 (2%)

Query: 1710 PSLGPPSEQDCMFGNGKGYRGKKATTVTGTPCQEWAAQEPHRHSTFIPGTNKWAGLEKNY 1769
            P+   PS Q+C   NG+ YRG   TTVTG  CQ W++  PH+HS   P      GL  NY
Sbjct: 18   PTETGPSVQECYHSNGQSYRGTYFTTVTGRTCQAWSSMTPHQHSR-TPEKYPNDGLISNY 76

Query: 1770 CRNPDGDINGPWCYTMNPRKLFDYCDIPLCA 1800
            CRNPD    GPWCYT +P   ++YC++  C+
Sbjct: 77   CRNPDCSA-GPWCYTTDPNVRWEYCNLTRCS 106


>gi|13346502 lipoprotein, Lp(a)-like 2 precursor [Homo sapiens]
          Length = 132

 Score =  210 bits (534), Expect = 1e-53
 Identities = 97/125 (77%), Positives = 102/125 (81%)

Query: 1   MEHKEVVLLLLLFLKSAAPEQSHVVQDCYHGDGQSYRGTYSTTVTGRTCQAWSSMTPHQH 60
           MEHKEVVLLLLLFLKSA  E    VQ+CYH +GQSYRGTY TTVTGRTCQAWSSMTPHQH
Sbjct: 1   MEHKEVVLLLLLFLKSAPTETGPSVQECYHSNGQSYRGTYFTTVTGRTCQAWSSMTPHQH 60

Query: 61  NRTTENYPNAGLIMNYCRNPDAVAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTP 120
           +RT E YPN GLI NYCRNPD  A P+CYT DP VRWEYCNLT+CSD EGT   P TV P
Sbjct: 61  SRTPEKYPNDGLISNYCRNPDCSAGPWCYTTDPNVRWEYCNLTRCSDDEGTVFVPLTVIP 120

Query: 121 VPSLE 125
           VPSLE
Sbjct: 121 VPSLE 125



 Score =  196 bits (498), Expect = 2e-49
 Identities = 89/116 (76%), Positives = 92/116 (79%)

Query: 927  EQAPTEQRPGVQECYHGNGQSYQGTYFITVTGRTCQAWSSMTPHSHSRTPAYYPNAGLIK 986
            + APTE  P VQECYH NGQSY+GTYF TVTGRTCQAWSSMTPH HSRTP  YPN GLI 
Sbjct: 15   KSAPTETGPSVQECYHSNGQSYRGTYFTTVTGRTCQAWSSMTPHQHSRTPEKYPNDGLIS 74

Query: 987  NYCRNPDPVAAPWCYTTDPSVRWEYCNLTRCSDAEWTAFVPPNVILAPSLEAFFEQ 1042
            NYCRNPD  A PWCYTTDP+VRWEYCNLTRCSD E T FVP  VI  PSLE  F Q
Sbjct: 75   NYCRNPDCSAGPWCYTTDPNVRWEYCNLTRCSDDEGTVFVPLTVIPVPSLEDSFIQ 130



 Score =  195 bits (495), Expect = 4e-49
 Identities = 87/111 (78%), Positives = 90/111 (81%)

Query: 129 EQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIM 188
           + APTE  P VQECYH NGQSYRGTY TTVTGRTCQAWSSMTPH HSRTPE YPN GLI 
Sbjct: 15  KSAPTETGPSVQECYHSNGQSYRGTYFTTVTGRTCQAWSSMTPHQHSRTPEKYPNDGLIS 74

Query: 189 NYCRNPDAVAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLE 239
           NYCRNPD  A P+CYT DP VRWEYCNLT+CSD EGT   P TV PVPSLE
Sbjct: 75  NYCRNPDCSAGPWCYTTDPNVRWEYCNLTRCSDDEGTVFVPLTVIPVPSLE 125



 Score =  195 bits (495), Expect = 4e-49
 Identities = 87/111 (78%), Positives = 90/111 (81%)

Query: 243 EQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIM 302
           + APTE  P VQECYH NGQSYRGTY TTVTGRTCQAWSSMTPH HSRTPE YPN GLI 
Sbjct: 15  KSAPTETGPSVQECYHSNGQSYRGTYFTTVTGRTCQAWSSMTPHQHSRTPEKYPNDGLIS 74

Query: 303 NYCRNPDAVAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLE 353
           NYCRNPD  A P+CYT DP VRWEYCNLT+CSD EGT   P TV PVPSLE
Sbjct: 75  NYCRNPDCSAGPWCYTTDPNVRWEYCNLTRCSDDEGTVFVPLTVIPVPSLE 125



 Score =  195 bits (495), Expect = 4e-49
 Identities = 87/111 (78%), Positives = 90/111 (81%)

Query: 357 EQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIM 416
           + APTE  P VQECYH NGQSYRGTY TTVTGRTCQAWSSMTPH HSRTPE YPN GLI 
Sbjct: 15  KSAPTETGPSVQECYHSNGQSYRGTYFTTVTGRTCQAWSSMTPHQHSRTPEKYPNDGLIS 74

Query: 417 NYCRNPDAVAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLE 467
           NYCRNPD  A P+CYT DP VRWEYCNLT+CSD EGT   P TV PVPSLE
Sbjct: 75  NYCRNPDCSAGPWCYTTDPNVRWEYCNLTRCSDDEGTVFVPLTVIPVPSLE 125



 Score =  195 bits (495), Expect = 4e-49
 Identities = 87/111 (78%), Positives = 90/111 (81%)

Query: 471 EQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIM 530
           + APTE  P VQECYH NGQSYRGTY TTVTGRTCQAWSSMTPH HSRTPE YPN GLI 
Sbjct: 15  KSAPTETGPSVQECYHSNGQSYRGTYFTTVTGRTCQAWSSMTPHQHSRTPEKYPNDGLIS 74

Query: 531 NYCRNPDAVAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLE 581
           NYCRNPD  A P+CYT DP VRWEYCNLT+CSD EGT   P TV PVPSLE
Sbjct: 75  NYCRNPDCSAGPWCYTTDPNVRWEYCNLTRCSDDEGTVFVPLTVIPVPSLE 125



 Score =  195 bits (495), Expect = 4e-49
 Identities = 87/111 (78%), Positives = 90/111 (81%)

Query: 585 EQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIM 644
           + APTE  P VQECYH NGQSYRGTY TTVTGRTCQAWSSMTPH HSRTPE YPN GLI 
Sbjct: 15  KSAPTETGPSVQECYHSNGQSYRGTYFTTVTGRTCQAWSSMTPHQHSRTPEKYPNDGLIS 74

Query: 645 NYCRNPDAVAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLE 695
           NYCRNPD  A P+CYT DP VRWEYCNLT+CSD EGT   P TV PVPSLE
Sbjct: 75  NYCRNPDCSAGPWCYTTDPNVRWEYCNLTRCSDDEGTVFVPLTVIPVPSLE 125



 Score =  195 bits (495), Expect = 4e-49
 Identities = 87/111 (78%), Positives = 90/111 (81%)

Query: 699 EQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIM 758
           + APTE  P VQECYH NGQSYRGTY TTVTGRTCQAWSSMTPH HSRTPE YPN GLI 
Sbjct: 15  KSAPTETGPSVQECYHSNGQSYRGTYFTTVTGRTCQAWSSMTPHQHSRTPEKYPNDGLIS 74

Query: 759 NYCRNPDAVAAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLE 809
           NYCRNPD  A P+CYT DP VRWEYCNLT+CSD EGT   P TV PVPSLE
Sbjct: 75  NYCRNPDCSAGPWCYTTDPNVRWEYCNLTRCSDDEGTVFVPLTVIPVPSLE 125



 Score =  194 bits (492), Expect = 1e-48
 Identities = 82/110 (74%), Positives = 92/110 (83%)

Query: 1603 EAAPTEQTPVVRQCYHGNGQSYRGTFSTTVTGRTCQSWSSMTPHRHQRTPENYPNDGLTM 1662
            ++APTE  P V++CYH NGQSYRGT+ TTVTGRTCQ+WSSMTPH+H RTPE YPNDGL  
Sbjct: 15   KSAPTETGPSVQECYHSNGQSYRGTYFTTVTGRTCQAWSSMTPHQHSRTPEKYPNDGLIS 74

Query: 1663 NYCRNPDADTGPWCFTMDPSIRWEYCNLTRCSDTEGTVVAPPTVIQVPSL 1712
            NYCRNPD   GPWC+T DP++RWEYCNLTRCSD EGTV  P TVI VPSL
Sbjct: 75   NYCRNPDCSAGPWCYTTDPNVRWEYCNLTRCSDDEGTVFVPLTVIPVPSL 124



 Score =  193 bits (491), Expect = 1e-48
 Identities = 85/111 (76%), Positives = 91/111 (81%)

Query: 813 EQAPTEQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIM 872
           + APTE  P VQECYH NGQSYRGTY TTVTGRTCQAWSSMTPH HSRTPE YPN GLI 
Sbjct: 15  KSAPTETGPSVQECYHSNGQSYRGTYFTTVTGRTCQAWSSMTPHQHSRTPEKYPNDGLIS 74

Query: 873 NYCRNPDPVAAPYCYTRDPSVRWEYCNLTQCSDAEGTAVAPPTITPIPSLE 923
           NYCRNPD  A P+CYT DP+VRWEYCNLT+CSD EGT   P T+ P+PSLE
Sbjct: 75  NYCRNPDCSAGPWCYTTDPNVRWEYCNLTRCSDDEGTVFVPLTVIPVPSLE 125



 Score =  179 bits (454), Expect = 2e-44
 Identities = 80/115 (69%), Positives = 87/115 (75%)

Query: 1039 FFEQALTEETPGVQDCYYHYGQSYRGTYSTTVTGRTCQAWSSMTPHQHSRTPENYPNAGL 1098
            F + A TE  P VQ+CY+  GQSYRGTY TTVTGRTCQAWSSMTPHQHSRTPE YPN GL
Sbjct: 13   FLKSAPTETGPSVQECYHSNGQSYRGTYFTTVTGRTCQAWSSMTPHQHSRTPEKYPNDGL 72

Query: 1099 TRNYCRNPDAEIRPWCYTMDPSVRWEYCNLTQCLVTESSVLATLTVVPDPSTEAS 1153
              NYCRNPD    PWCYT DP+VRWEYCNLT+C   E +V   LTV+P PS E S
Sbjct: 73   ISNYCRNPDCSAGPWCYTTDPNVRWEYCNLTRCSDDEGTVFVPLTVIPVPSLEDS 127



 Score =  173 bits (438), Expect = 2e-42
 Identities = 74/111 (66%), Positives = 85/111 (76%)

Query: 1261 EQAPTEQSPTVQDCYHGDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTR 1320
            + APTE  P+VQ+CYH +GQSYRG++ TTVTGRTCQ+WSSMTPH H RT E YPN GL  
Sbjct: 15   KSAPTETGPSVQECYHSNGQSYRGTYFTTVTGRTCQAWSSMTPHQHSRTPEKYPNDGLIS 74

Query: 1321 NYCRNPDAEIRPWCYTMDPSVRWEYCNLTQCPVMESTLLTTPTVVPVPSTE 1371
            NYCRNPD    PWCYT DP+VRWEYCNLT+C   E T+    TV+PVPS E
Sbjct: 75   NYCRNPDCSAGPWCYTTDPNVRWEYCNLTRCSDDEGTVFVPLTVIPVPSLE 125



 Score =  171 bits (432), Expect = 9e-42
 Identities = 74/111 (66%), Positives = 83/111 (74%)

Query: 1489 EQAPPEKSPVVQDCYHGDGRSYRGISSTTVTGRTCQSWSSMIPHWHQRTPENYPNAGLTE 1548
            + AP E  P VQ+CYH +G+SYRG   TTVTGRTCQ+WSSM PH H RTPE YPN GL  
Sbjct: 15   KSAPTETGPSVQECYHSNGQSYRGTYFTTVTGRTCQAWSSMTPHQHSRTPEKYPNDGLIS 74

Query: 1549 NYCRNPDSGKQPWCYTTDPCVRWEYCNLTQCSETESGVLETPTVVPVPSME 1599
            NYCRNPD    PWCYTTDP VRWEYCNLT+CS+ E  V    TV+PVPS+E
Sbjct: 75   NYCRNPDCSAGPWCYTTDPNVRWEYCNLTRCSDDEGTVFVPLTVIPVPSLE 125



 Score =  164 bits (416), Expect = 6e-40
 Identities = 69/105 (65%), Positives = 78/105 (74%)

Query: 1155 EEAPTEQSPGVQDCYHGDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTR 1214
            + APTE  P VQ+CYH +GQSYRG++ TTVTGRTCQ+WSSMTPH H RT E YPN GL  
Sbjct: 15   KSAPTETGPSVQECYHSNGQSYRGTYFTTVTGRTCQAWSSMTPHQHSRTPEKYPNDGLIS 74

Query: 1215 NYCRNPDAEISPWCYTMDPNVRWEYCNLTQCPVTESSVLATSTAV 1259
            NYCRNPD    PWCYT DPNVRWEYCNLT+C   E +V    T +
Sbjct: 75   NYCRNPDCSAGPWCYTTDPNVRWEYCNLTRCSDDEGTVFVPLTVI 119



 Score =  164 bits (414), Expect = 1e-39
 Identities = 72/111 (64%), Positives = 79/111 (71%)

Query: 1375 EEAPTENSTGVQDCYRGDGQSYRGTLSTTITGRTCQSWSSMTPHWHRRIPLYYPNAGLTR 1434
            + APTE    VQ+CY  +GQSYRGT  TT+TGRTCQ+WSSMTPH H R P  YPN GL  
Sbjct: 15   KSAPTETGPSVQECYHSNGQSYRGTYFTTVTGRTCQAWSSMTPHQHSRTPEKYPNDGLIS 74

Query: 1435 NYCRNPDAEIRPWCYTMDPSVRWEYCNLTRCPVTESSVLTTPTVAPVPSTE 1485
            NYCRNPD    PWCYT DP+VRWEYCNLTRC   E +V    TV PVPS E
Sbjct: 75   NYCRNPDCSAGPWCYTTDPNVRWEYCNLTRCSDDEGTVFVPLTVIPVPSLE 125



 Score = 89.7 bits (221), Expect = 3e-17
 Identities = 42/91 (46%), Positives = 54/91 (59%), Gaps = 2/91 (2%)

Query: 1710 PSLGPPSEQDCMFGNGKGYRGKKATTVTGTPCQEWAAQEPHRHSTFIPGTNKWAGLEKNY 1769
            P+   PS Q+C   NG+ YRG   TTVTG  CQ W++  PH+HS   P      GL  NY
Sbjct: 18   PTETGPSVQECYHSNGQSYRGTYFTTVTGRTCQAWSSMTPHQHSR-TPEKYPNDGLISNY 76

Query: 1770 CRNPDGDINGPWCYTMNPRKLFDYCDIPLCA 1800
            CRNPD    GPWCYT +P   ++YC++  C+
Sbjct: 77   CRNPDCSA-GPWCYTTDPNVRWEYCNLTRCS 106


>gi|4758502 hyaluronan binding protein 2 preproprotein [Homo sapiens]
          Length = 560

 Score =  191 bits (486), Expect = 5e-48
 Identities = 142/432 (32%), Positives = 203/432 (46%), Gaps = 70/432 (16%)

Query: 1665 CRNPDADTGPWCFTMDPSIRWEYC-NLTRCSD----TEGTVVAPPTVI-QVPSLGPPSEQ 1718
            C++P   TGP C  + P  R   C N   CS     ++ T   P     +   +G     
Sbjct: 138  CKHPY--TGPSCSQVVPVCRPNPCQNGATCSRHKRRSKFTCACPDQFKGKFCEIG---SD 192

Query: 1719 DCMFGNGKGYRGKKATTVTGTPCQEWAAQE--PHRHSTFIPGTNKWAGLEKNYCRNPDGD 1776
            DC  G+G  YRGK   TV    C  W +       ++ F+         E N+CRNPD D
Sbjct: 193  DCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNPDAD 252

Query: 1777 INGPWCY--TMNPRKLFDYCDIPLCASSS-----------------FD-CGKPQVEPKKC 1816
               PWC+    N +  ++YCD+  C++                   FD CGK ++  +K 
Sbjct: 253  -EKPWCFIKVTNDKVKWEYCDVSACSAQDVAYPEESPTEPSTKLPGFDSCGKTEIAERKI 311

Query: 1817 PGSIVGGCVAHPHSWPWQVSLRTRFGK-------HFCGGTLISPEWVLTAAHCLKKSSRP 1869
               I GG  +     PWQ SL++           HFCGG LI P WVLTAAHC    +R 
Sbjct: 312  K-RIYGGFKSTAGKHPWQASLQSSLPLTISMPQGHFCGGALIHPCWVLTAAHCTDIKTR- 369

Query: 1870 SSYKVILGAHQEVNLESHVQEIEVSRLFL--------EPTQADIALLKLS----RPAVIT 1917
               KV+LG       E H Q   V ++F         E    DIALLKL       A+ +
Sbjct: 370  -HLKVVLGDQDLKKEEFHEQSFRVEKIFKYSHYNERDEIPHNDIALLKLKPVDGHCALES 428

Query: 1918 DKVMPACLPSPDYMVTARTECYITGWGETQGTFGTGLLKEAQLLVIENEVCNHYKY---- 1973
              V   CLP   +   + +EC+I+GWG T+   G+  L +A++ +I N +CN  +     
Sbjct: 429  KYVKTVCLPDGSF--PSGSECHISGWGVTETGKGSRQLLDAKVKLIANTLCNSRQLYDHM 486

Query: 1974 -----ICAEHLAR-GTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYARVS 2027
                 ICA +L + G D+CQGDSGGPL C +   Y + G+ SWGL C +  +PGVY +V+
Sbjct: 487  IDDSMICAGNLQKPGQDTCQGDSGGPLTCEKDGTYYVYGIVSWGLECGK--RPGVYTQVT 544

Query: 2028 RFVTWIEGMMRN 2039
            +F+ WI+  +++
Sbjct: 545  KFLNWIKATIKS 556



 Score = 79.7 bits (195), Expect = 3e-14
 Identities = 41/110 (37%), Positives = 58/110 (52%), Gaps = 12/110 (10%)

Query: 1164 GVQDCYHGDGQSYRGSFSTTVTGRTCQSWSS---MTPHWHQRTTEYYPNGGLTRNYCRNP 1220
            G  DCY GDG SYRG  + TV    C  W+S   +  +++    +   +G    N+CRNP
Sbjct: 190  GSDDCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNP 249

Query: 1221 DAEISPWCYTMDPN--VRWEYCNLTQCPVTESSVLATSTAVSEQAPTEQS 1268
            DA+  PWC+    N  V+WEYC+++ C        A   A  E++PTE S
Sbjct: 250  DADEKPWCFIKVTNDKVKWEYCDVSACS-------AQDVAYPEESPTEPS 292



 Score = 77.4 bits (189), Expect = 1e-13
 Identities = 39/107 (36%), Positives = 59/107 (55%), Gaps = 9/107 (8%)

Query: 1273 DCYHGDGQSYRGSFSTTVTGRTCQSWSS---MTPHWHQRTTEYYPNGGLTRNYCRNPDAE 1329
            DCY GDG SYRG  + TV    C  W+S   +  +++    +   +G    N+CRNPDA+
Sbjct: 193  DCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNPDAD 252

Query: 1330 IRPWCY--TMDPSVRWEYCNLTQCPVMESTLLTTPTVVPV-PSTELP 1373
             +PWC+    +  V+WEYC+++ C   +   +  P   P  PST+LP
Sbjct: 253  EKPWCFIKVTNDKVKWEYCDVSACSAQD---VAYPEESPTEPSTKLP 296



 Score = 76.6 bits (187), Expect = 2e-13
 Identities = 39/113 (34%), Positives = 58/113 (51%), Gaps = 5/113 (4%)

Query: 1501 DCYHGDGRSYRGISSTTVTGRTCQSWSS--MIPHWHQRTPENYPNAGLTE-NYCRNPDSG 1557
            DCY GDG SYRG  + TV    C  W+S  ++   +    E+    G+ E N+CRNPD+ 
Sbjct: 193  DCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNPDAD 252

Query: 1558 KQPWCY--TTDPCVRWEYCNLTQCSETESGVLETPTVVPVPSMEAHSEAAPTE 1608
            ++PWC+   T+  V+WEYC+++ CS  +    E     P   +        TE
Sbjct: 253  EKPWCFIKVTNDKVKWEYCDVSACSAQDVAYPEESPTEPSTKLPGFDSCGKTE 305



 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 37/110 (33%), Positives = 60/110 (54%), Gaps = 9/110 (8%)

Query: 1384 GVQDCYRGDGQSYRGTLSTTITGRTCQSWSS---MTPHWHRRIPLYYPNAGLTRNYCRNP 1440
            G  DCY GDG SYRG ++ T+    C  W+S   +  +++  +     +     N+CRNP
Sbjct: 190  GSDDCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNP 249

Query: 1441 DAEIRPWCY--TMDPSVRWEYCNLTRCPVTESSVLTTPTVAPV-PSTEAP 1487
            DA+ +PWC+    +  V+WEYC+++ C   +   +  P  +P  PST+ P
Sbjct: 250  DADEKPWCFIKVTNDKVKWEYCDVSACSAQD---VAYPEESPTEPSTKLP 296



 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 44/121 (36%), Positives = 64/121 (52%), Gaps = 17/121 (14%)

Query: 27  DCYHGDGQSYRGTYSTTVTGRTCQAWSS--MTPHQHNRTTENYPNAGL-IMNYCRNPDAV 83
           DCY GDG SYRG  + TV    C  W+S  +    +N   E+    G+   N+CRNPDA 
Sbjct: 193 DCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNPDAD 252

Query: 84  AAPYCYTR--DPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPGVQE 141
             P+C+ +  +  V+WEYC+++ CS  +   VA P        E+P+E  P+ + PG   
Sbjct: 253 EKPWCFIKVTNDKVKWEYCDVSACSAQD---VAYPE-------ESPTE--PSTKLPGFDS 300

Query: 142 C 142
           C
Sbjct: 301 C 301



 Score = 72.4 bits (176), Expect = 4e-12
 Identities = 42/127 (33%), Positives = 60/127 (47%), Gaps = 23/127 (18%)

Query: 1050 GVQDCYYHYGQSYRGTYSTTVTGRTCQAWSS--MTPHQHSRTPENYPNAGL-TRNYCRNP 1106
            G  DCY   G SYRG  + TV    C  W+S  +    ++   E+    G+   N+CRNP
Sbjct: 190  GSDDCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNP 249

Query: 1107 DAEIRPWCY--TMDPSVRWEYCNLTQCLVTESSVLATLTVVPDPSTEASSEEAPTEQS-- 1162
            DA+ +PWC+    +  V+WEYC+++ C   +                A  EE+PTE S  
Sbjct: 250  DADEKPWCFIKVTNDKVKWEYCDVSACSAQD---------------VAYPEESPTEPSTK 294

Query: 1163 -PGVQDC 1168
             PG   C
Sbjct: 295  LPGFDSC 301



 Score = 72.4 bits (176), Expect = 4e-12
 Identities = 39/110 (35%), Positives = 54/110 (49%), Gaps = 7/110 (6%)

Query: 1616 CYHGNGQSYRGTFSTTVTGRTCQSWSS--MTPHRHQRTPENYPNDGL-TMNYCRNPDADT 1672
            CY G+G SYRG  + TV    C  W+S  +    +    E+    G+   N+CRNPDAD 
Sbjct: 194  CYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNPDADE 253

Query: 1673 GPWCF--TMDPSIRWEYCNLTRCSDTEGTVVAPPTVIQVPSLGPPSEQDC 1720
             PWCF    +  ++WEYC+++ CS  +  V  P      PS   P    C
Sbjct: 254  KPWCFIKVTNDKVKWEYCDVSACSAQD--VAYPEESPTEPSTKLPGFDSC 301



 Score = 68.2 bits (165), Expect = 8e-11
 Identities = 42/124 (33%), Positives = 65/124 (52%), Gaps = 17/124 (13%)

Query: 138 GVQECYHGNGQSYRGTYSTTVTGRTCQAWSS--MTPHSHSRTPEYYPNAGL-IMNYCRNP 194
           G  +CY G+G SYRG  + TV    C  W+S  +   +++   E     G+   N+CRNP
Sbjct: 190 GSDDCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNP 249

Query: 195 DAVAAPYCYTR--DPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 252
           DA   P+C+ +  +  V+WEYC+++ CS  +   VA P        E+P+E  P+ + PG
Sbjct: 250 DADEKPWCFIKVTNDKVKWEYCDVSACSAQD---VAYPE-------ESPTE--PSTKLPG 297

Query: 253 VQEC 256
              C
Sbjct: 298 FDSC 301



 Score = 68.2 bits (165), Expect = 8e-11
 Identities = 42/124 (33%), Positives = 65/124 (52%), Gaps = 17/124 (13%)

Query: 252 GVQECYHGNGQSYRGTYSTTVTGRTCQAWSS--MTPHSHSRTPEYYPNAGL-IMNYCRNP 308
           G  +CY G+G SYRG  + TV    C  W+S  +   +++   E     G+   N+CRNP
Sbjct: 190 GSDDCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNP 249

Query: 309 DAVAAPYCYTR--DPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 366
           DA   P+C+ +  +  V+WEYC+++ CS  +   VA P        E+P+E  P+ + PG
Sbjct: 250 DADEKPWCFIKVTNDKVKWEYCDVSACSAQD---VAYPE-------ESPTE--PSTKLPG 297

Query: 367 VQEC 370
              C
Sbjct: 298 FDSC 301



 Score = 68.2 bits (165), Expect = 8e-11
 Identities = 42/124 (33%), Positives = 65/124 (52%), Gaps = 17/124 (13%)

Query: 366 GVQECYHGNGQSYRGTYSTTVTGRTCQAWSS--MTPHSHSRTPEYYPNAGL-IMNYCRNP 422
           G  +CY G+G SYRG  + TV    C  W+S  +   +++   E     G+   N+CRNP
Sbjct: 190 GSDDCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNP 249

Query: 423 DAVAAPYCYTR--DPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 480
           DA   P+C+ +  +  V+WEYC+++ CS  +   VA P        E+P+E  P+ + PG
Sbjct: 250 DADEKPWCFIKVTNDKVKWEYCDVSACSAQD---VAYPE-------ESPTE--PSTKLPG 297

Query: 481 VQEC 484
              C
Sbjct: 298 FDSC 301



 Score = 68.2 bits (165), Expect = 8e-11
 Identities = 42/124 (33%), Positives = 65/124 (52%), Gaps = 17/124 (13%)

Query: 480 GVQECYHGNGQSYRGTYSTTVTGRTCQAWSS--MTPHSHSRTPEYYPNAGL-IMNYCRNP 536
           G  +CY G+G SYRG  + TV    C  W+S  +   +++   E     G+   N+CRNP
Sbjct: 190 GSDDCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNP 249

Query: 537 DAVAAPYCYTR--DPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 594
           DA   P+C+ +  +  V+WEYC+++ CS  +   VA P        E+P+E  P+ + PG
Sbjct: 250 DADEKPWCFIKVTNDKVKWEYCDVSACSAQD---VAYPE-------ESPTE--PSTKLPG 297

Query: 595 VQEC 598
              C
Sbjct: 298 FDSC 301



 Score = 68.2 bits (165), Expect = 8e-11
 Identities = 42/124 (33%), Positives = 65/124 (52%), Gaps = 17/124 (13%)

Query: 594 GVQECYHGNGQSYRGTYSTTVTGRTCQAWSS--MTPHSHSRTPEYYPNAGL-IMNYCRNP 650
           G  +CY G+G SYRG  + TV    C  W+S  +   +++   E     G+   N+CRNP
Sbjct: 190 GSDDCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNP 249

Query: 651 DAVAAPYCYTR--DPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 708
           DA   P+C+ +  +  V+WEYC+++ CS  +   VA P        E+P+E  P+ + PG
Sbjct: 250 DADEKPWCFIKVTNDKVKWEYCDVSACSAQD---VAYPE-------ESPTE--PSTKLPG 297

Query: 709 VQEC 712
              C
Sbjct: 298 FDSC 301



 Score = 68.2 bits (165), Expect = 8e-11
 Identities = 42/124 (33%), Positives = 65/124 (52%), Gaps = 17/124 (13%)

Query: 708 GVQECYHGNGQSYRGTYSTTVTGRTCQAWSS--MTPHSHSRTPEYYPNAGL-IMNYCRNP 764
           G  +CY G+G SYRG  + TV    C  W+S  +   +++   E     G+   N+CRNP
Sbjct: 190 GSDDCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNP 249

Query: 765 DAVAAPYCYTR--DPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 822
           DA   P+C+ +  +  V+WEYC+++ CS  +   VA P        E+P+E  P+ + PG
Sbjct: 250 DADEKPWCFIKVTNDKVKWEYCDVSACSAQD---VAYPE-------ESPTE--PSTKLPG 297

Query: 823 VQEC 826
              C
Sbjct: 298 FDSC 301



 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 41/124 (33%), Positives = 64/124 (51%), Gaps = 17/124 (13%)

Query: 822 GVQECYHGNGQSYRGTYSTTVTGRTCQAWSS--MTPHSHSRTPEYYPNAGL-IMNYCRNP 878
           G  +CY G+G SYRG  + TV    C  W+S  +   +++   E     G+   N+CRNP
Sbjct: 190 GSDDCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNP 249

Query: 879 DPVAAPYCYTR--DPSVRWEYCNLTQCSDAEGTAVAPPTITPIPSLEAPSEQAPTEQRPG 936
           D    P+C+ +  +  V+WEYC+++ CS  +   VA P        E+P+E  P+ + PG
Sbjct: 250 DADEKPWCFIKVTNDKVKWEYCDVSACSAQD---VAYPE-------ESPTE--PSTKLPG 297

Query: 937 VQEC 940
              C
Sbjct: 298 FDSC 301



 Score = 62.4 bits (150), Expect = 4e-09
 Identities = 31/88 (35%), Positives = 48/88 (54%), Gaps = 5/88 (5%)

Query: 936  GVQECYHGNGQSYQGTYFITVTGRTCQAWSS--MTPHSHSRTPAYYPNAGLIK-NYCRNP 992
            G  +CY G+G SY+G    TV    C  W+S  +   +++         G+ + N+CRNP
Sbjct: 190  GSDDCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNP 249

Query: 993  DPVAAPWCY--TTDPSVRWEYCNLTRCS 1018
            D    PWC+   T+  V+WEYC+++ CS
Sbjct: 250  DADEKPWCFIKVTNDKVKWEYCDVSACS 277


>gi|4504383 HGF activator preproprotein [Homo sapiens]
          Length = 655

 Score =  185 bits (470), Expect = 3e-46
 Identities = 168/639 (26%), Positives = 247/639 (38%), Gaps = 101/639 (15%)

Query: 1461 NLTRCPVTESSVLTTPTVAPVPSTEAPSEQAPPEKSPVVQDCYHGDGRSYRGISSTTVTG 1520
            N T  P   + +L T   +  P+T AP  + P +   +          S     + T  G
Sbjct: 48   NATATPAIPT-ILVTSVTSETPATSAPEAEGP-QSGGLPPPPRAVPSSSSPQAQALTEDG 105

Query: 1521 RTCQSWSSMIPHWHQRTPENYPNAGLTENYCRNPDSGKQPWCYTTDPCVR---WEYCNLT 1577
            R C            R P  Y   G   + C +  S  + WC TT    R   W YC   
Sbjct: 106  RPC------------RFPFRY--GGRMLHACTSEGSAHRKWCATTHNYDRDRAWGYC--V 149

Query: 1578 QCSETESGVLETPTVVPVPSMEAHSEAAPTEQTPVVRQCYHGNGQSYRGTFSTTVTGRTC 1637
            + +    G          P +   S      Q P          QSY  +     TG+ C
Sbjct: 150  EATPPPGGPAALDPCASGPCLNGGS--CSNTQDP----------QSYHCSCPRAFTGKDC 197

Query: 1638 QSWSSMTPHRHQRTPENYPNDGLTMNYCRNPDADTG-PWC-------FTMDPSIRWEYCN 1689
             +       R++          +   +    +   G  WC           P +    C+
Sbjct: 198  GTEKCFDETRYEYLEGGDRWARVRQGHVEQCECFGGRTWCEGTRHTACLSSPCLNGGTCH 257

Query: 1690 LTRCSDTEGTVVAPPTVIQVPSLGPPSEQDCMFGNGKGYRGKKATTVTGTPCQEWAA--- 1746
            L   + T      P    ++ ++ P  ++ C  GNG GYRG  +T+ +G  C  W +   
Sbjct: 258  LIVATGTTVCACPPGFAGRLCNIEP--DERCFLGNGTGYRGVASTSASGLSCLAWNSDLL 315

Query: 1747 -QEPHRHSTFIPGTNKWAGLEKN-YCRNPDGDINGPWCYTMNPRKL-FDYCDIPLCASSS 1803
             QE H  S    G     GL  + YCRNPD D   PWCY +    L ++YC +  C S +
Sbjct: 316  YQELHVDSV---GAAALLGLGPHAYCRNPDND-ERPWCYVVKDSALSWEYCRLEACESLT 371

Query: 1804 F--------------------DCGKPQVEPKKCPGSIVGGCVAHPHSWPWQVSLRTRFGK 1843
                                  CG+   +       I+GG  + P S PW  ++    G 
Sbjct: 372  RVQLSPDLLATLPEPASPGRQACGRRHKKRTFLRPRIIGGSSSLPGSHPWLAAIY--IGD 429

Query: 1844 HFCGGTLISPEWVLTAAHCLKKSSRPSSYKVILGAH---------QEVNLESHVQEIEVS 1894
             FC G+L+   WV++AAHC   S    S  V+LG H         Q   +E ++     S
Sbjct: 430  SFCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQHFFNRTTDVTQTFGIEKYIPYTLYS 489

Query: 1895 RLFLEPTQADIALLKLS----RPAVITDKVMPACLPSPDYMVTARTECYITGWGETQGTF 1950
                 P+  D+ L++L     R A  +  V P CLP P     A  +C I GWG      
Sbjct: 490  --VFNPSDHDLVLIRLKKKGDRCATRSQFVQPICLPEPGSTFPAGHKCQIAGWGHLDENV 547

Query: 1951 G--TGLLKEAQLLVIENEVCNHYKY---------ICAEHLARGTDSCQGDSGGPLVCFEK 1999
               +  L+EA + ++ +  C+  +          +CA +    +D+CQGDSGGPL C + 
Sbjct: 548  SGYSSSLREALVPLVADHKCSSPEVYGADISPNMLCAGYFDCKSDACQGDSGGPLACEKN 607

Query: 2000 DKYILQGVTSWGLGCARPNKPGVYARVSRFVTWIEGMMR 2038
                L G+ SWG GC R +KPGVY RV+ +V WI   +R
Sbjct: 608  GVAYLYGIISWGDGCGRLHKPGVYTRVANYVDWINDRIR 646



 Score = 82.4 bits (202), Expect = 4e-15
 Identities = 91/377 (24%), Positives = 131/377 (34%), Gaps = 57/377 (15%)

Query: 1028 PNVILAPSLEAFFEQALTEETPGVQDCYYHYGQSYRGTYSTTVTGRTCQAWSSMTPHQHS 1087
            PN    P++      ++T ETP              G  S  +        SS +P   +
Sbjct: 47   PNATATPAIPTILVTSVTSETPATS------APEAEGPQSGGLPPPPRAVPSSSSPQAQA 100

Query: 1088 RTPENYP------NAGLTRNYCRNPDAEIRPWCYTM---DPSVRWEYCNLTQCLVTESSV 1138
             T +  P        G   + C +  +  R WC T    D    W YC            
Sbjct: 101  LTEDGRPCRFPFRYGGRMLHACTSEGSAHRKWCATTHNYDRDRAWGYC------------ 148

Query: 1139 LATLTVVPDPSTEASSEEAPTEQSPGVQDCYHG-DGQSYRGSFSTTVTGRTCQSWSSMTP 1197
               +   P P   A+ +   +        C +  D QSY  S     TG+ C      T 
Sbjct: 149  ---VEATPPPGGPAALDPCASGPCLNGGSCSNTQDPQSYHCSCPRAFTGKDCG-----TE 200

Query: 1198 HWHQRTTEYYPNGGLTRNYCRNPDAEISP------WCYTMDPNVRWEYCNLTQC--PVTE 1249
                 T   Y  GG      R    E         WC       R   C  + C    T 
Sbjct: 201  KCFDETRYEYLEGGDRWARVRQGHVEQCECFGGRTWC----EGTRHTACLSSPCLNGGTC 256

Query: 1250 SSVLATSTAVSEQAPTEQSPTV-----QDCYHGDGQSYRGSFSTTVTGRTCQSWSS--MT 1302
              ++AT T V    P            + C+ G+G  YRG  ST+ +G +C +W+S  + 
Sbjct: 257  HLIVATGTTVCACPPGFAGRLCNIEPDERCFLGNGTGYRGVASTSASGLSCLAWNSDLLY 316

Query: 1303 PHWHQRTTEYYPNGGLTRN-YCRNPDAEIRPWCYTM-DPSVRWEYCNLTQCPVMESTLLT 1360
               H  +       GL  + YCRNPD + RPWCY + D ++ WEYC L  C  +    L+
Sbjct: 317  QELHVDSVGAAALLGLGPHAYCRNPDNDERPWCYVVKDSALSWEYCRLEACESLTRVQLS 376

Query: 1361 TPTVVPVPSTELPSEEA 1377
               +  +P    P  +A
Sbjct: 377  PDLLATLPEPASPGRQA 393



 Score = 80.1 bits (196), Expect = 2e-14
 Identities = 96/379 (25%), Positives = 131/379 (34%), Gaps = 66/379 (17%)

Query: 1137 SVLATLTVVPDPSTEASSEEAPTEQSPGVQDCYHG-DGQSYRGSFSTTVTGRTCQSWSSM 1195
            ++L T      P+T A   E P  QS G+          S   + + T  GR C+     
Sbjct: 57   TILVTSVTSETPATSAPEAEGP--QSGGLPPPPRAVPSSSSPQAQALTEDGRPCRF---- 110

Query: 1196 TPHWHQRTTEYYPNGGLTRNYCRNPDAEISPWCYTM---DPNVRWEYCNLTQCPVTESSV 1252
                       +  GG   + C +  +    WC T    D +  W YC     P    + 
Sbjct: 111  ----------PFRYGGRMLHACTSEGSAHRKWCATTHNYDRDRAWGYCVEATPPPGGPAA 160

Query: 1253 LATSTAVSEQAPTEQSPTVQDCYHG-------DGQSYRGSFSTTVTGRTCQSWSSMTPHW 1305
            L          P    P    C +G       D QSY  S     TG+ C      T   
Sbjct: 161  LD---------PCASGP----CLNGGSCSNTQDPQSYHCSCPRAFTGKDCG-----TEKC 202

Query: 1306 HQRTTEYYPNGGLTRNYCRNPDAEI------RPWCYTMDPSVRWEYCNLTQC---PVMES 1356
               T   Y  GG      R    E       R WC       R   C  + C        
Sbjct: 203  FDETRYEYLEGGDRWARVRQGHVEQCECFGGRTWC----EGTRHTACLSSPCLNGGTCHL 258

Query: 1357 TLLTTPTVVPVPSTELPSEEAPTENSTGVQDCYRGDGQSYRGTLSTTITGRTCQSWSSMT 1416
             + T  TV   P    P       N    + C+ G+G  YRG  ST+ +G +C +W+S  
Sbjct: 259  IVATGTTVCACP----PGFAGRLCNIEPDERCFLGNGTGYRGVASTSASGLSCLAWNSDL 314

Query: 1417 PHWHRRIPLYYPNAGL---TRNYCRNPDAEIRPWCYTM-DPSVRWEYCNLTRCPVTESSV 1472
             +    +      A L      YCRNPD + RPWCY + D ++ WEYC L  C       
Sbjct: 315  LYQELHVDSVGAAALLGLGPHAYCRNPDNDERPWCYVVKDSALSWEYCRLEACESLTRVQ 374

Query: 1473 LTTPTVAPVPSTEAPSEQA 1491
            L+   +A +P   +P  QA
Sbjct: 375  LSPDLLATLPEPASPGRQA 393



 Score = 74.7 bits (182), Expect = 9e-13
 Identities = 37/110 (33%), Positives = 54/110 (49%), Gaps = 4/110 (3%)

Query: 824 QECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMN---YCRNPDP 880
           + C+ GNG  YRG  ST+ +G +C AW+S   +           A L +    YCRNPD 
Sbjct: 284 ERCFLGNGTGYRGVASTSASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAYCRNPDN 343

Query: 881 VAAPYCY-TRDPSVRWEYCNLTQCSDAEGTAVAPPTITPIPSLEAPSEQA 929
              P+CY  +D ++ WEYC L  C       ++P  +  +P   +P  QA
Sbjct: 344 DERPWCYVVKDSALSWEYCRLEACESLTRVQLSPDLLATLPEPASPGRQA 393



 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 37/110 (33%), Positives = 53/110 (48%), Gaps = 4/110 (3%)

Query: 140 QECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMN---YCRNPDA 196
           + C+ GNG  YRG  ST+ +G +C AW+S   +           A L +    YCRNPD 
Sbjct: 284 ERCFLGNGTGYRGVASTSASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAYCRNPDN 343

Query: 197 VAAPYCY-TRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQA 245
              P+CY  +D  + WEYC L  C       ++P  +  +P   +P  QA
Sbjct: 344 DERPWCYVVKDSALSWEYCRLEACESLTRVQLSPDLLATLPEPASPGRQA 393



 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 37/110 (33%), Positives = 53/110 (48%), Gaps = 4/110 (3%)

Query: 254 QECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMN---YCRNPDA 310
           + C+ GNG  YRG  ST+ +G +C AW+S   +           A L +    YCRNPD 
Sbjct: 284 ERCFLGNGTGYRGVASTSASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAYCRNPDN 343

Query: 311 VAAPYCY-TRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQA 359
              P+CY  +D  + WEYC L  C       ++P  +  +P   +P  QA
Sbjct: 344 DERPWCYVVKDSALSWEYCRLEACESLTRVQLSPDLLATLPEPASPGRQA 393



 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 37/110 (33%), Positives = 53/110 (48%), Gaps = 4/110 (3%)

Query: 368 QECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMN---YCRNPDA 424
           + C+ GNG  YRG  ST+ +G +C AW+S   +           A L +    YCRNPD 
Sbjct: 284 ERCFLGNGTGYRGVASTSASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAYCRNPDN 343

Query: 425 VAAPYCY-TRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQA 473
              P+CY  +D  + WEYC L  C       ++P  +  +P   +P  QA
Sbjct: 344 DERPWCYVVKDSALSWEYCRLEACESLTRVQLSPDLLATLPEPASPGRQA 393



 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 37/110 (33%), Positives = 53/110 (48%), Gaps = 4/110 (3%)

Query: 482 QECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMN---YCRNPDA 538
           + C+ GNG  YRG  ST+ +G +C AW+S   +           A L +    YCRNPD 
Sbjct: 284 ERCFLGNGTGYRGVASTSASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAYCRNPDN 343

Query: 539 VAAPYCY-TRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQA 587
              P+CY  +D  + WEYC L  C       ++P  +  +P   +P  QA
Sbjct: 344 DERPWCYVVKDSALSWEYCRLEACESLTRVQLSPDLLATLPEPASPGRQA 393



 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 37/110 (33%), Positives = 53/110 (48%), Gaps = 4/110 (3%)

Query: 596 QECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMN---YCRNPDA 652
           + C+ GNG  YRG  ST+ +G +C AW+S   +           A L +    YCRNPD 
Sbjct: 284 ERCFLGNGTGYRGVASTSASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAYCRNPDN 343

Query: 653 VAAPYCY-TRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQA 701
              P+CY  +D  + WEYC L  C       ++P  +  +P   +P  QA
Sbjct: 344 DERPWCYVVKDSALSWEYCRLEACESLTRVQLSPDLLATLPEPASPGRQA 393



 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 37/110 (33%), Positives = 53/110 (48%), Gaps = 4/110 (3%)

Query: 710 QECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMN---YCRNPDA 766
           + C+ GNG  YRG  ST+ +G +C AW+S   +           A L +    YCRNPD 
Sbjct: 284 ERCFLGNGTGYRGVASTSASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAYCRNPDN 343

Query: 767 VAAPYCY-TRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQA 815
              P+CY  +D  + WEYC L  C       ++P  +  +P   +P  QA
Sbjct: 344 DERPWCYVVKDSALSWEYCRLEACESLTRVQLSPDLLATLPEPASPGRQA 393



 Score = 71.6 bits (174), Expect = 7e-12
 Identities = 37/108 (34%), Positives = 53/108 (49%), Gaps = 4/108 (3%)

Query: 28  CYHGDGQSYRGTYSTTVTGRTCQAWSSMTPHQHNRTTENYPNAGLIMN---YCRNPDAVA 84
           C+ G+G  YRG  ST+ +G +C AW+S   +Q          A L +    YCRNPD   
Sbjct: 286 CFLGNGTGYRGVASTSASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAYCRNPDNDE 345

Query: 85  APYCY-TRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQA 131
            P+CY  +D  + WEYC L  C       ++P  +  +P   +P  QA
Sbjct: 346 RPWCYVVKDSALSWEYCRLEACESLTRVQLSPDLLATLPEPASPGRQA 393



 Score = 62.8 bits (151), Expect = 3e-09
 Identities = 40/121 (33%), Positives = 55/121 (45%), Gaps = 14/121 (11%)

Query: 938  QECYHGNGQSYQGTYFITVTGRTCQAWSS--MTPHSHSRTPAYYPNAGLIKN-YCRNPDP 994
            + C+ GNG  Y+G    + +G +C AW+S  +    H  +       GL  + YCRNPD 
Sbjct: 284  ERCFLGNGTGYRGVASTSASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAYCRNPDN 343

Query: 995  VAAPWCYTT-DPSVRWEYCNLTRCSDAEWTAFVPPNVILAPSLEAFFEQALTEETPGVQD 1053
               PWCY   D ++ WEYC L  C            V L+P L A   +     +PG Q 
Sbjct: 344  DERPWCYVVKDSALSWEYCRLEACESL-------TRVQLSPDLLATLPE---PASPGRQA 393

Query: 1054 C 1054
            C
Sbjct: 394  C 394


>gi|58533163 hepatocyte growth factor isoform 2 precursor [Homo
            sapiens]
          Length = 290

 Score =  184 bits (467), Expect = 8e-46
 Identities = 86/201 (42%), Positives = 107/201 (53%), Gaps = 33/201 (16%)

Query: 1494 EKSPVVQDCYHGDGRSYRGISSTTVTGRTCQSWSSMIPHWHQRTPENYPNAGLTENYCRN 1553
            E    +++C  G GRSY+G  S T +G  CQ WSSMIPH H   P +Y    L ENYCRN
Sbjct: 120  ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRN 179

Query: 1554 PDSGK-QPWCYTTDPCVRWEYCNLTQCSETESGVLETPTVVPVPSMEAHSEAAPTEQTPV 1612
            P   +  PWC+T++P VR+E C++ QCSE E                             
Sbjct: 180  PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 210

Query: 1613 VRQCYHGNGQSYRGTFSTTVTGRTCQSWSSMTPHRHQRTPENYPNDGLTMNYCRNPDADT 1672
               C   NG+SYRG    T +G+ CQ W   TPHRH+  PE YP+ G   NYCRNPD   
Sbjct: 211  ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 267

Query: 1673 GPWCFTMDPSIRWEYCNLTRC 1693
             PWC+T+DP  RWEYC +  C
Sbjct: 268  RPWCYTLDPHTRWEYCAIKTC 288



 Score =  181 bits (459), Expect = 6e-45
 Identities = 83/201 (41%), Positives = 107/201 (53%), Gaps = 33/201 (16%)

Query: 932  EQRPGVQECYHGNGQSYQGTYFITVTGRTCQAWSSMTPHSHSRTPAYYPNAGLIKNYCRN 991
            E +  ++ C  G G+SY+GT  IT +G  CQ WSSM PH HS  P+ Y    L +NYCRN
Sbjct: 120  ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRN 179

Query: 992  P-DPVAAPWCYTTDPSVRWEYCNLTRCSDAEWTAFVPPNVILAPSLEAFFEQALTEETPG 1050
            P      PWC+T++P VR+E C++ +CS+ E                             
Sbjct: 180  PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 210

Query: 1051 VQDCYYHYGQSYRGTYSTTVTGRTCQAWSSMTPHQHSRTPENYPNAGLTRNYCRNPDAEI 1110
               C    G+SYRG    T +G+ CQ W   TPH+H   PE YP+ G   NYCRNPD + 
Sbjct: 211  ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 267

Query: 1111 RPWCYTMDPSVRWEYCNLTQC 1131
            RPWCYT+DP  RWEYC +  C
Sbjct: 268  RPWCYTLDPHTRWEYCAIKTC 288



 Score =  173 bits (438), Expect = 2e-42
 Identities = 81/201 (40%), Positives = 104/201 (51%), Gaps = 33/201 (16%)

Query: 1380 ENSTGVQDCYRGDGQSYRGTLSTTITGRTCQSWSSMTPHWHRRIPLYYPNAGLTRNYCRN 1439
            EN   +++C  G G+SY+GT+S T +G  CQ WSSM PH H  +P  Y    L  NYCRN
Sbjct: 120  ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRN 179

Query: 1440 PDAEIR-PWCYTMDPSVRWEYCNLTRCPVTESSVLTTPTVAPVPSTEAPSEQAPPEKSPV 1498
            P  E   PWC+T +P VR+E C++ +C   E                             
Sbjct: 180  PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 210

Query: 1499 VQDCYHGDGRSYRGISSTTVTGRTCQSWSSMIPHWHQRTPENYPNAGLTENYCRNPDSGK 1558
               C   +G SYRG+   T +G+ CQ W    PH H+  PE YP+ G  +NYCRNPD   
Sbjct: 211  ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 267

Query: 1559 QPWCYTTDPCVRWEYCNLTQC 1579
            +PWCYT DP  RWEYC +  C
Sbjct: 268  RPWCYTLDPHTRWEYCAIKTC 288



 Score =  172 bits (437), Expect = 2e-42
 Identities = 82/203 (40%), Positives = 105/203 (51%), Gaps = 33/203 (16%)

Query: 1044 LTEETPGVQDCYYHYGQSYRGTYSTTVTGRTCQAWSSMTPHQHSRTPENYPNAGLTRNYC 1103
            L E    +++C    G+SY+GT S T +G  CQ WSSM PH+HS  P +Y    L  NYC
Sbjct: 118  LYENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYC 177

Query: 1104 RNPDAEI-RPWCYTMDPSVRWEYCNLTQCLVTESSVLATLTVVPDPSTEASSEEAPTEQS 1162
            RNP  E   PWC+T +P VR+E C++ QC   E                           
Sbjct: 178  RNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE--------------------------- 210

Query: 1163 PGVQDCYHGDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRNPDA 1222
                 C   +G+SYRG    T +G+ CQ W   TPH H+   E YP+ G   NYCRNPD 
Sbjct: 211  -----CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDG 265

Query: 1223 EISPWCYTMDPNVRWEYCNLTQC 1245
            +  PWCYT+DP+ RWEYC +  C
Sbjct: 266  QPRPWCYTLDPHTRWEYCAIKTC 288



 Score =  171 bits (433), Expect = 7e-42
 Identities = 80/193 (41%), Positives = 101/193 (52%), Gaps = 25/193 (12%)

Query: 1160 EQSPGVQDCYHGDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRN 1219
            E    +++C  G G+SY+G+ S T +G  CQ WSSM PH H      Y    L  NYCRN
Sbjct: 120  ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRN 179

Query: 1220 PDAEIS-PWCYTMDPNVRWEYCNLTQCPVTESSVLATSTAVSEQAPTEQSPTVQDCYHGD 1278
            P  E   PWC+T +P VR+E C++ QC   E                        C   +
Sbjct: 180  PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE------------------------CMTCN 215

Query: 1279 GQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRNPDAEIRPWCYTMD 1338
            G+SYRG    T +G+ CQ W   TPH H+   E YP+ G   NYCRNPD + RPWCYT+D
Sbjct: 216  GESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLD 275

Query: 1339 PSVRWEYCNLTQC 1351
            P  RWEYC +  C
Sbjct: 276  PHTRWEYCAIKTC 288



 Score =  171 bits (433), Expect = 7e-42
 Identities = 80/201 (39%), Positives = 104/201 (51%), Gaps = 33/201 (16%)

Query: 1266 EQSPTVQDCYHGDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRN 1325
            E    +++C  G G+SY+G+ S T +G  CQ WSSM PH H      Y    L  NYCRN
Sbjct: 120  ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRN 179

Query: 1326 PDAEIR-PWCYTMDPSVRWEYCNLTQCPVMESTLLTTPTVVPVPSTELPSEEAPTENSTG 1384
            P  E   PWC+T +P VR+E C++ QC  +E                             
Sbjct: 180  PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 210

Query: 1385 VQDCYRGDGQSYRGTLSTTITGRTCQSWSSMTPHWHRRIPLYYPNAGLTRNYCRNPDAEI 1444
               C   +G+SYRG +  T +G+ CQ W   TPH H+ +P  YP+ G   NYCRNPD + 
Sbjct: 211  ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 267

Query: 1445 RPWCYTMDPSVRWEYCNLTRC 1465
            RPWCYT+DP  RWEYC +  C
Sbjct: 268  RPWCYTLDPHTRWEYCAIKTC 288



 Score =  169 bits (427), Expect = 3e-41
 Identities = 82/201 (40%), Positives = 101/201 (50%), Gaps = 33/201 (16%)

Query: 134 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 193
           E +  ++ C  G G+SY+GT S T +G  CQ WSSM PH HS  P  Y    L  NYCRN
Sbjct: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRN 179

Query: 194 PDAV-AAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 252
           P      P+C+T +P VR+E C++ QCS+ E                             
Sbjct: 180 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 210

Query: 253 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 312
              C   NG+SYRG    T +G+ CQ W   TPH H   PE YP+ G   NYCRNPD   
Sbjct: 211 ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 267

Query: 313 APYCYTRDPGVRWEYCNLTQC 333
            P+CYT DP  RWEYC +  C
Sbjct: 268 RPWCYTLDPHTRWEYCAIKTC 288



 Score =  169 bits (427), Expect = 3e-41
 Identities = 82/201 (40%), Positives = 101/201 (50%), Gaps = 33/201 (16%)

Query: 248 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 307
           E +  ++ C  G G+SY+GT S T +G  CQ WSSM PH HS  P  Y    L  NYCRN
Sbjct: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRN 179

Query: 308 PDAV-AAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 366
           P      P+C+T +P VR+E C++ QCS+ E                             
Sbjct: 180 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 210

Query: 367 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 426
              C   NG+SYRG    T +G+ CQ W   TPH H   PE YP+ G   NYCRNPD   
Sbjct: 211 ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 267

Query: 427 APYCYTRDPGVRWEYCNLTQC 447
            P+CYT DP  RWEYC +  C
Sbjct: 268 RPWCYTLDPHTRWEYCAIKTC 288



 Score =  169 bits (427), Expect = 3e-41
 Identities = 82/201 (40%), Positives = 101/201 (50%), Gaps = 33/201 (16%)

Query: 362 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 421
           E +  ++ C  G G+SY+GT S T +G  CQ WSSM PH HS  P  Y    L  NYCRN
Sbjct: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRN 179

Query: 422 PDAV-AAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 480
           P      P+C+T +P VR+E C++ QCS+ E                             
Sbjct: 180 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 210

Query: 481 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 540
              C   NG+SYRG    T +G+ CQ W   TPH H   PE YP+ G   NYCRNPD   
Sbjct: 211 ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 267

Query: 541 APYCYTRDPGVRWEYCNLTQC 561
            P+CYT DP  RWEYC +  C
Sbjct: 268 RPWCYTLDPHTRWEYCAIKTC 288



 Score =  169 bits (427), Expect = 3e-41
 Identities = 82/201 (40%), Positives = 101/201 (50%), Gaps = 33/201 (16%)

Query: 476 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 535
           E +  ++ C  G G+SY+GT S T +G  CQ WSSM PH HS  P  Y    L  NYCRN
Sbjct: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRN 179

Query: 536 PDAV-AAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 594
           P      P+C+T +P VR+E C++ QCS+ E                             
Sbjct: 180 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 210

Query: 595 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 654
              C   NG+SYRG    T +G+ CQ W   TPH H   PE YP+ G   NYCRNPD   
Sbjct: 211 ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 267

Query: 655 APYCYTRDPGVRWEYCNLTQC 675
            P+CYT DP  RWEYC +  C
Sbjct: 268 RPWCYTLDPHTRWEYCAIKTC 288



 Score =  169 bits (427), Expect = 3e-41
 Identities = 82/201 (40%), Positives = 101/201 (50%), Gaps = 33/201 (16%)

Query: 590 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 649
           E +  ++ C  G G+SY+GT S T +G  CQ WSSM PH HS  P  Y    L  NYCRN
Sbjct: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRN 179

Query: 650 PDAV-AAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 708
           P      P+C+T +P VR+E C++ QCS+ E                             
Sbjct: 180 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 210

Query: 709 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 768
              C   NG+SYRG    T +G+ CQ W   TPH H   PE YP+ G   NYCRNPD   
Sbjct: 211 ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 267

Query: 769 APYCYTRDPGVRWEYCNLTQC 789
            P+CYT DP  RWEYC +  C
Sbjct: 268 RPWCYTLDPHTRWEYCAIKTC 288



 Score =  168 bits (426), Expect = 4e-41
 Identities = 82/201 (40%), Positives = 101/201 (50%), Gaps = 33/201 (16%)

Query: 704 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 763
           E +  ++ C  G G+SY+GT S T +G  CQ WSSM PH HS  P  Y    L  NYCRN
Sbjct: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRN 179

Query: 764 PDAV-AAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 822
           P      P+C+T +P VR+E C++ QCS+ E                             
Sbjct: 180 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 210

Query: 823 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDPVA 882
              C   NG+SYRG    T +G+ CQ W   TPH H   PE YP+ G   NYCRNPD   
Sbjct: 211 ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 267

Query: 883 APYCYTRDPSVRWEYCNLTQC 903
            P+CYT DP  RWEYC +  C
Sbjct: 268 RPWCYTLDPHTRWEYCAIKTC 288



 Score =  168 bits (426), Expect = 4e-41
 Identities = 81/201 (40%), Positives = 100/201 (49%), Gaps = 33/201 (16%)

Query: 818  EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 877
            E +  ++ C  G G+SY+GT S T +G  CQ WSSM PH HS  P  Y    L  NYCRN
Sbjct: 120  ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRN 179

Query: 878  P-DPVAAPYCYTRDPSVRWEYCNLTQCSDAEGTAVAPPTITPIPSLEAPSEQAPTEQRPG 936
            P      P+C+T +P VR+E C++ QCS+                               
Sbjct: 180  PRGEEGGPWCFTSNPEVRYEVCDIPQCSEV------------------------------ 209

Query: 937  VQECYHGNGQSYQGTYFITVTGRTCQAWSSMTPHSHSRTPAYYPNAGLIKNYCRNPDPVA 996
              EC   NG+SY+G    T +G+ CQ W   TPH H   P  YP+ G   NYCRNPD   
Sbjct: 210  --ECMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 267

Query: 997  APWCYTTDPSVRWEYCNLTRC 1017
             PWCYT DP  RWEYC +  C
Sbjct: 268  RPWCYTLDPHTRWEYCAIKTC 288



 Score =  166 bits (421), Expect = 2e-40
 Identities = 80/201 (39%), Positives = 102/201 (50%), Gaps = 33/201 (16%)

Query: 20  EQSHVVQDCYHGDGQSYRGTYSTTVTGRTCQAWSSMTPHQHNRTTENYPNAGLIMNYCRN 79
           E    +++C  G G+SY+GT S T +G  CQ WSSM PH+H+    +Y    L  NYCRN
Sbjct: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRN 179

Query: 80  PDAV-AAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 138
           P      P+C+T +P VR+E C++ QCS+ E                             
Sbjct: 180 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 210

Query: 139 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 198
              C   NG+SYRG    T +G+ CQ W   TPH H   PE YP+ G   NYCRNPD   
Sbjct: 211 ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 267

Query: 199 APYCYTRDPGVRWEYCNLTQC 219
            P+CYT DP  RWEYC +  C
Sbjct: 268 RPWCYTLDPHTRWEYCAIKTC 288



 Score =  166 bits (420), Expect = 2e-40
 Identities = 81/193 (41%), Positives = 102/193 (52%), Gaps = 25/193 (12%)

Query: 1608 EQTPVVRQCYHGNGQSYRGTFSTTVTGRTCQSWSSMTPHRHQRTPENYPNDGLTMNYCRN 1667
            E    +R C  G G+SY+GT S T +G  CQ WSSM PH H   P +Y    L  NYCRN
Sbjct: 120  ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRN 179

Query: 1668 PDADT-GPWCFTMDPSIRWEYCNLTRCSDTEGTVVAPPTVIQVPSLGPPSEQDCMFGNGK 1726
            P  +  GPWCFT +P +R+E C++ +CS+ E                      CM  NG+
Sbjct: 180  PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------CMTCNGE 217

Query: 1727 GYRGKKATTVTGTPCQEWAAQEPHRHSTFIPGTNKWAGLEKNYCRNPDGDINGPWCYTMN 1786
             YRG    T +G  CQ W  Q PHRH  F+P      G + NYCRNPDG    PWCYT++
Sbjct: 218  SYRGLMDHTESGKICQRWDHQTPHRHK-FLPERYPDKGFDDNYCRNPDGQPR-PWCYTLD 275

Query: 1787 PRKLFDYCDIPLC 1799
            P   ++YC I  C
Sbjct: 276  PHTRWEYCAIKTC 288



 Score = 99.0 bits (245), Expect = 4e-20
 Identities = 47/130 (36%), Positives = 69/130 (53%), Gaps = 16/130 (12%)

Query: 1718 QDCMFGNGKGYRGKKATTVTGTPCQEWAAQEPHRHSTFIPGTNKWAGLEKNYCRNPDGDI 1777
            ++C+ G G+ Y+G  + T +G  CQ W++  PH HS F+P + +   L++NYCRNP G+ 
Sbjct: 126  RNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-FLPSSYRGKDLQENYCRNPRGEE 184

Query: 1778 NGPWCYTMNPRKLFDYCDIPLCASSSFDCGKPQVEPKKCPGSIVGGCVAHPHS------W 1831
             GPWC+T NP   ++ CDIP C+         +VE   C G    G + H  S      W
Sbjct: 185  GGPWCFTSNPEVRYEVCDIPQCS---------EVECMTCNGESYRGLMDHTESGKICQRW 235

Query: 1832 PWQVSLRTRF 1841
              Q   R +F
Sbjct: 236  DHQTPHRHKF 245



 Score = 95.1 bits (235), Expect = 6e-19
 Identities = 41/87 (47%), Positives = 51/87 (58%), Gaps = 2/87 (2%)

Query: 19  PEQSHVVQDCYHGDGQSYRGTYSTTVTGRTCQAWSSMTPHQHNRTTENYPNAGLIMNYCR 78
           P+ S V  +C   +G+SYRG    T +G+ CQ W   TPH+H    E YP+ G   NYCR
Sbjct: 204 PQCSEV--ECMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCR 261

Query: 79  NPDAVAAPYCYTRDPGVRWEYCNLTQC 105
           NPD    P+CYT DP  RWEYC +  C
Sbjct: 262 NPDGQPRPWCYTLDPHTRWEYCAIKTC 288


>gi|110815798 ovochymase 1 [Homo sapiens]
          Length = 1134

 Score =  178 bits (452), Expect = 4e-44
 Identities = 101/249 (40%), Positives = 130/249 (52%), Gaps = 21/249 (8%)

Query: 1806 CGKPQVEPKKCPGSIVGGCVAHPHSWPWQVSLRTRFGKHFCGGTLISPEWVLTAAHCLKK 1865
            CG P   P+     I GG  A PH WPWQV LR   G + CGG +I+P W+LTAAHC++ 
Sbjct: 561  CGIPPFSPQWLSRRIAGGEEACPHCWPWQVGLRF-LGDYQCGGAIINPVWILTAAHCVQL 619

Query: 1866 SSRPSSYKVILGAHQEVNLESHVQEIEVSRLFLEPT------QADIALLKLSRPAVITDK 1919
             + P S+ +I G H     ES  Q      + +          +DIAL++LS P      
Sbjct: 620  KNNPLSWTIIAGDHDRNLKESTEQVRRAKHIIVHEDFNTLSYDSDIALIQLSSPLEYNSV 679

Query: 1920 VMPACLPSPDYMVTARTECYITGWGETQGTFG-TGLLKEAQLLVIENEVCNHYKY----- 1973
            V P CLP     + +   C +TGWG      G    L++ Q+ V+E EVC H  Y     
Sbjct: 680  VRPVCLPHSAEPLFSSEICAVTGWGSISADGGLASRLQQIQVHVLEREVCEHTYYSAHPG 739

Query: 1974 ------ICAEHLARGT-DSCQGDSGGPLVC-FEKDKYILQGVTSWGLGCARPNKPGVYAR 2025
                  ICA   A G  D CQGDSGGPLVC  E   ++L G+ SWG GC +P KPGV+AR
Sbjct: 740  GITEKMICAGFAASGEKDFCQGDSGGPLVCRHENGPFVLYGIVSWGAGCVQPWKPGVFAR 799

Query: 2026 VSRFVTWIE 2034
            V  F+ WI+
Sbjct: 800  VMIFLDWIQ 808



 Score =  117 bits (293), Expect = 1e-25
 Identities = 87/273 (31%), Positives = 122/273 (44%), Gaps = 41/273 (15%)

Query: 1801 SSSFDCGKPQVEPKKCPGSIVGGCVAHPHSW--------PWQVSLRTRFGKHFCGGTLIS 1852
            S    CG   V  K    ++     +   SW        PWQVSL++    HFCGG+LI 
Sbjct: 20   SLGLKCGIRMVNMKSKEPAVGSRFFSRISSWRNSTVTGHPWQVSLKSD-EHHFCGGSLIQ 78

Query: 1853 PEWVLTAAHCLKKSSRP--SSYKVILGAHQEVNLESHVQEIEVSRLFLEP-------TQA 1903
             + V+TAAHCL   S     +  V  G +     +   Q I VS++   P          
Sbjct: 79   EDRVVTAAHCLDSLSEKQLKNITVTSGEYSLFQKDKQEQNIPVSKIITHPEYNSREYMSP 138

Query: 1904 DIALLKLSRPAVITDKVMPACLPSPDYMVTARTECYITGWGETQGTFG-TGLLKEAQLLV 1962
            DIALL L       + V P CLP  D  V     C  +GWG+   T   + +L+E +L +
Sbjct: 139  DIALLYLKHKVKFGNAVQPICLPDSDDKVEPGILCLSSGWGKISKTSEYSNVLQEMELPI 198

Query: 1963 IENEVCNHY-----------KYICAEHLARGTDSCQGDSGGPLVCFEKDK-YILQGVTSW 2010
            +++  CN               +CA     G D+CQGDSGGPLVC      +IL G+TSW
Sbjct: 199  MDDRACNTVLKSMNLPPLGRTMLCAGFPDWGMDACQGDSGGPLVCRRGGGIWILAGITSW 258

Query: 2011 GLGCARPNKP----------GVYARVSRFVTWI 2033
              GCA  + P          G++++VS  + +I
Sbjct: 259  VAGCAGGSVPVRNNHVKASLGIFSKVSELMDFI 291


>gi|116256363 transmembrane protease, serine 13 [Homo sapiens]
          Length = 567

 Score =  177 bits (449), Expect = 9e-44
 Identities = 101/239 (42%), Positives = 135/239 (56%), Gaps = 19/239 (7%)

Query: 1818 GSIVGGCVAHPHSWPWQVSLRTRFGK-HFCGGTLISPEWVLTAAHC--LKKSSRPSSYKV 1874
            G IVGG +A    WPWQVSL   FG  H CGGTLI  +WVLTAAHC  + +      +KV
Sbjct: 324  GRIVGGALASDSKWPWQVSLH--FGTTHICGGTLIDAQWVLTAAHCFFVTREKVLEGWKV 381

Query: 1875 ILGA---HQEVNLESHVQEIEVSRLFLEPTQADIALLKLSRPAVITDKVMPACLPSPDYM 1931
              G    HQ     S  + I  S    E    DIAL++LS+P  ++  + PACLP     
Sbjct: 382  YAGTSNLHQLPEAASIAEIIINSNYTDEEDDYDIALMRLSKPLTLSAHIHPACLPMHGQT 441

Query: 1932 VTARTECYITGWGETQGTFG--TGLLKEAQLLVIENEVCNHY---------KYICAEHLA 1980
             +    C+ITG+G+T+ T    +  L+E Q+ +I+ + CN Y         + +CA  L 
Sbjct: 442  FSLNETCWITGFGKTRETDDKTSPFLREVQVNLIDFKKCNDYLVYDSYLTPRMMCAGDLR 501

Query: 1981 RGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYARVSRFVTWIEGMMRN 2039
             G DSCQGDSGGPLVC + +++ L GVTSWG GC + NKPGVY +V+  + WI   M +
Sbjct: 502  GGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWIYSKMES 560


>gi|58533165 hepatocyte growth factor isoform 4 precursor [Homo
            sapiens]
          Length = 285

 Score =  177 bits (448), Expect = 1e-43
 Identities = 85/201 (42%), Positives = 106/201 (52%), Gaps = 38/201 (18%)

Query: 1494 EKSPVVQDCYHGDGRSYRGISSTTVTGRTCQSWSSMIPHWHQRTPENYPNAGLTENYCRN 1553
            E    +++C  G GRSY+G  S T +G  CQ WSSMIPH H     +Y    L ENYCRN
Sbjct: 120  ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEH-----SYRGKDLQENYCRN 174

Query: 1554 PDSGK-QPWCYTTDPCVRWEYCNLTQCSETESGVLETPTVVPVPSMEAHSEAAPTEQTPV 1612
            P   +  PWC+T++P VR+E C++ QCSE E                             
Sbjct: 175  PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 205

Query: 1613 VRQCYHGNGQSYRGTFSTTVTGRTCQSWSSMTPHRHQRTPENYPNDGLTMNYCRNPDADT 1672
               C   NG+SYRG    T +G+ CQ W   TPHRH+  PE YP+ G   NYCRNPD   
Sbjct: 206  ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 262

Query: 1673 GPWCFTMDPSIRWEYCNLTRC 1693
             PWC+T+DP  RWEYC +  C
Sbjct: 263  RPWCYTLDPHTRWEYCAIKTC 283



 Score =  174 bits (441), Expect = 8e-43
 Identities = 82/201 (40%), Positives = 105/201 (52%), Gaps = 38/201 (18%)

Query: 932  EQRPGVQECYHGNGQSYQGTYFITVTGRTCQAWSSMTPHSHSRTPAYYPNAGLIKNYCRN 991
            E +  ++ C  G G+SY+GT  IT +G  CQ WSSM PH HS     Y    L +NYCRN
Sbjct: 120  ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYCRN 174

Query: 992  P-DPVAAPWCYTTDPSVRWEYCNLTRCSDAEWTAFVPPNVILAPSLEAFFEQALTEETPG 1050
            P      PWC+T++P VR+E C++ +CS+ E                             
Sbjct: 175  PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 205

Query: 1051 VQDCYYHYGQSYRGTYSTTVTGRTCQAWSSMTPHQHSRTPENYPNAGLTRNYCRNPDAEI 1110
               C    G+SYRG    T +G+ CQ W   TPH+H   PE YP+ G   NYCRNPD + 
Sbjct: 206  ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 262

Query: 1111 RPWCYTMDPSVRWEYCNLTQC 1131
            RPWCYT+DP  RWEYC +  C
Sbjct: 263  RPWCYTLDPHTRWEYCAIKTC 283



 Score =  167 bits (424), Expect = 7e-41
 Identities = 80/193 (41%), Positives = 101/193 (52%), Gaps = 30/193 (15%)

Query: 1160 EQSPGVQDCYHGDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRN 1219
            E    +++C  G G+SY+G+ S T +G  CQ WSSM PH H      Y    L  NYCRN
Sbjct: 120  ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYCRN 174

Query: 1220 PDAEIS-PWCYTMDPNVRWEYCNLTQCPVTESSVLATSTAVSEQAPTEQSPTVQDCYHGD 1278
            P  E   PWC+T +P VR+E C++ QC   E                        C   +
Sbjct: 175  PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE------------------------CMTCN 210

Query: 1279 GQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRNPDAEIRPWCYTMD 1338
            G+SYRG    T +G+ CQ W   TPH H+   E YP+ G   NYCRNPD + RPWCYT+D
Sbjct: 211  GESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLD 270

Query: 1339 PSVRWEYCNLTQC 1351
            P  RWEYC +  C
Sbjct: 271  PHTRWEYCAIKTC 283



 Score =  167 bits (424), Expect = 7e-41
 Identities = 80/201 (39%), Positives = 104/201 (51%), Gaps = 38/201 (18%)

Query: 1266 EQSPTVQDCYHGDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRN 1325
            E    +++C  G G+SY+G+ S T +G  CQ WSSM PH H      Y    L  NYCRN
Sbjct: 120  ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYCRN 174

Query: 1326 PDAEIR-PWCYTMDPSVRWEYCNLTQCPVMESTLLTTPTVVPVPSTELPSEEAPTENSTG 1384
            P  E   PWC+T +P VR+E C++ QC  +E                             
Sbjct: 175  PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 205

Query: 1385 VQDCYRGDGQSYRGTLSTTITGRTCQSWSSMTPHWHRRIPLYYPNAGLTRNYCRNPDAEI 1444
               C   +G+SYRG +  T +G+ CQ W   TPH H+ +P  YP+ G   NYCRNPD + 
Sbjct: 206  ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 262

Query: 1445 RPWCYTMDPSVRWEYCNLTRC 1465
            RPWCYT+DP  RWEYC +  C
Sbjct: 263  RPWCYTLDPHTRWEYCAIKTC 283



 Score =  166 bits (420), Expect = 2e-40
 Identities = 80/201 (39%), Positives = 102/201 (50%), Gaps = 38/201 (18%)

Query: 1380 ENSTGVQDCYRGDGQSYRGTLSTTITGRTCQSWSSMTPHWHRRIPLYYPNAGLTRNYCRN 1439
            EN   +++C  G G+SY+GT+S T +G  CQ WSSM PH H      Y    L  NYCRN
Sbjct: 120  ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYCRN 174

Query: 1440 PDAEIR-PWCYTMDPSVRWEYCNLTRCPVTESSVLTTPTVAPVPSTEAPSEQAPPEKSPV 1498
            P  E   PWC+T +P VR+E C++ +C   E                             
Sbjct: 175  PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 205

Query: 1499 VQDCYHGDGRSYRGISSTTVTGRTCQSWSSMIPHWHQRTPENYPNAGLTENYCRNPDSGK 1558
               C   +G SYRG+   T +G+ CQ W    PH H+  PE YP+ G  +NYCRNPD   
Sbjct: 206  ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 262

Query: 1559 QPWCYTTDPCVRWEYCNLTQC 1579
            +PWCYT DP  RWEYC +  C
Sbjct: 263  RPWCYTLDPHTRWEYCAIKTC 283



 Score =  165 bits (417), Expect = 5e-40
 Identities = 81/203 (39%), Positives = 103/203 (50%), Gaps = 38/203 (18%)

Query: 1044 LTEETPGVQDCYYHYGQSYRGTYSTTVTGRTCQAWSSMTPHQHSRTPENYPNAGLTRNYC 1103
            L E    +++C    G+SY+GT S T +G  CQ WSSM PH+HS     Y    L  NYC
Sbjct: 118  LYENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYC 172

Query: 1104 RNPDAEI-RPWCYTMDPSVRWEYCNLTQCLVTESSVLATLTVVPDPSTEASSEEAPTEQS 1162
            RNP  E   PWC+T +P VR+E C++ QC   E                           
Sbjct: 173  RNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE--------------------------- 205

Query: 1163 PGVQDCYHGDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRNPDA 1222
                 C   +G+SYRG    T +G+ CQ W   TPH H+   E YP+ G   NYCRNPD 
Sbjct: 206  -----CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDG 260

Query: 1223 EISPWCYTMDPNVRWEYCNLTQC 1245
            +  PWCYT+DP+ RWEYC +  C
Sbjct: 261  QPRPWCYTLDPHTRWEYCAIKTC 283



 Score =  162 bits (410), Expect = 3e-39
 Identities = 81/201 (40%), Positives = 100/201 (49%), Gaps = 38/201 (18%)

Query: 134 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 193
           E +  ++ C  G G+SY+GT S T +G  CQ WSSM PH HS     Y    L  NYCRN
Sbjct: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYCRN 174

Query: 194 PDAV-AAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 252
           P      P+C+T +P VR+E C++ QCS+ E                             
Sbjct: 175 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 205

Query: 253 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 312
              C   NG+SYRG    T +G+ CQ W   TPH H   PE YP+ G   NYCRNPD   
Sbjct: 206 ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 262

Query: 313 APYCYTRDPGVRWEYCNLTQC 333
            P+CYT DP  RWEYC +  C
Sbjct: 263 RPWCYTLDPHTRWEYCAIKTC 283



 Score =  162 bits (410), Expect = 3e-39
 Identities = 81/201 (40%), Positives = 100/201 (49%), Gaps = 38/201 (18%)

Query: 248 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 307
           E +  ++ C  G G+SY+GT S T +G  CQ WSSM PH HS     Y    L  NYCRN
Sbjct: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYCRN 174

Query: 308 PDAV-AAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 366
           P      P+C+T +P VR+E C++ QCS+ E                             
Sbjct: 175 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 205

Query: 367 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 426
              C   NG+SYRG    T +G+ CQ W   TPH H   PE YP+ G   NYCRNPD   
Sbjct: 206 ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 262

Query: 427 APYCYTRDPGVRWEYCNLTQC 447
            P+CYT DP  RWEYC +  C
Sbjct: 263 RPWCYTLDPHTRWEYCAIKTC 283



 Score =  162 bits (410), Expect = 3e-39
 Identities = 81/201 (40%), Positives = 100/201 (49%), Gaps = 38/201 (18%)

Query: 362 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 421
           E +  ++ C  G G+SY+GT S T +G  CQ WSSM PH HS     Y    L  NYCRN
Sbjct: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYCRN 174

Query: 422 PDAV-AAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 480
           P      P+C+T +P VR+E C++ QCS+ E                             
Sbjct: 175 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 205

Query: 481 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 540
              C   NG+SYRG    T +G+ CQ W   TPH H   PE YP+ G   NYCRNPD   
Sbjct: 206 ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 262

Query: 541 APYCYTRDPGVRWEYCNLTQC 561
            P+CYT DP  RWEYC +  C
Sbjct: 263 RPWCYTLDPHTRWEYCAIKTC 283



 Score =  162 bits (410), Expect = 3e-39
 Identities = 81/201 (40%), Positives = 100/201 (49%), Gaps = 38/201 (18%)

Query: 476 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 535
           E +  ++ C  G G+SY+GT S T +G  CQ WSSM PH HS     Y    L  NYCRN
Sbjct: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYCRN 174

Query: 536 PDAV-AAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 594
           P      P+C+T +P VR+E C++ QCS+ E                             
Sbjct: 175 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 205

Query: 595 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 654
              C   NG+SYRG    T +G+ CQ W   TPH H   PE YP+ G   NYCRNPD   
Sbjct: 206 ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 262

Query: 655 APYCYTRDPGVRWEYCNLTQC 675
            P+CYT DP  RWEYC +  C
Sbjct: 263 RPWCYTLDPHTRWEYCAIKTC 283



 Score =  162 bits (410), Expect = 3e-39
 Identities = 81/201 (40%), Positives = 100/201 (49%), Gaps = 38/201 (18%)

Query: 590 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 649
           E +  ++ C  G G+SY+GT S T +G  CQ WSSM PH HS     Y    L  NYCRN
Sbjct: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYCRN 174

Query: 650 PDAV-AAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 708
           P      P+C+T +P VR+E C++ QCS+ E                             
Sbjct: 175 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 205

Query: 709 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 768
              C   NG+SYRG    T +G+ CQ W   TPH H   PE YP+ G   NYCRNPD   
Sbjct: 206 ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 262

Query: 769 APYCYTRDPGVRWEYCNLTQC 789
            P+CYT DP  RWEYC +  C
Sbjct: 263 RPWCYTLDPHTRWEYCAIKTC 283



 Score =  162 bits (409), Expect = 4e-39
 Identities = 80/201 (39%), Positives = 101/201 (50%), Gaps = 38/201 (18%)

Query: 20  EQSHVVQDCYHGDGQSYRGTYSTTVTGRTCQAWSSMTPHQHNRTTENYPNAGLIMNYCRN 79
           E    +++C  G G+SY+GT S T +G  CQ WSSM PH+H+     Y    L  NYCRN
Sbjct: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYCRN 174

Query: 80  PDAV-AAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 138
           P      P+C+T +P VR+E C++ QCS+ E                             
Sbjct: 175 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 205

Query: 139 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDAVA 198
              C   NG+SYRG    T +G+ CQ W   TPH H   PE YP+ G   NYCRNPD   
Sbjct: 206 ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 262

Query: 199 APYCYTRDPGVRWEYCNLTQC 219
            P+CYT DP  RWEYC +  C
Sbjct: 263 RPWCYTLDPHTRWEYCAIKTC 283



 Score =  162 bits (409), Expect = 4e-39
 Identities = 81/201 (40%), Positives = 100/201 (49%), Gaps = 38/201 (18%)

Query: 704 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 763
           E +  ++ C  G G+SY+GT S T +G  CQ WSSM PH HS     Y    L  NYCRN
Sbjct: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYCRN 174

Query: 764 PDAV-AAPYCYTRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQAPTEQRPG 822
           P      P+C+T +P VR+E C++ QCS+ E                             
Sbjct: 175 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------------- 205

Query: 823 VQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRNPDPVA 882
              C   NG+SYRG    T +G+ CQ W   TPH H   PE YP+ G   NYCRNPD   
Sbjct: 206 ---CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 262

Query: 883 APYCYTRDPSVRWEYCNLTQC 903
            P+CYT DP  RWEYC +  C
Sbjct: 263 RPWCYTLDPHTRWEYCAIKTC 283



 Score =  162 bits (409), Expect = 4e-39
 Identities = 80/201 (39%), Positives = 99/201 (49%), Gaps = 38/201 (18%)

Query: 818  EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 877
            E +  ++ C  G G+SY+GT S T +G  CQ WSSM PH HS     Y    L  NYCRN
Sbjct: 120  ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-----YRGKDLQENYCRN 174

Query: 878  P-DPVAAPYCYTRDPSVRWEYCNLTQCSDAEGTAVAPPTITPIPSLEAPSEQAPTEQRPG 936
            P      P+C+T +P VR+E C++ QCS+                               
Sbjct: 175  PRGEEGGPWCFTSNPEVRYEVCDIPQCSEV------------------------------ 204

Query: 937  VQECYHGNGQSYQGTYFITVTGRTCQAWSSMTPHSHSRTPAYYPNAGLIKNYCRNPDPVA 996
              EC   NG+SY+G    T +G+ CQ W   TPH H   P  YP+ G   NYCRNPD   
Sbjct: 205  --ECMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP 262

Query: 997  APWCYTTDPSVRWEYCNLTRC 1017
             PWCYT DP  RWEYC +  C
Sbjct: 263  RPWCYTLDPHTRWEYCAIKTC 283



 Score =  159 bits (401), Expect = 3e-38
 Identities = 80/193 (41%), Positives = 101/193 (52%), Gaps = 30/193 (15%)

Query: 1608 EQTPVVRQCYHGNGQSYRGTFSTTVTGRTCQSWSSMTPHRHQRTPENYPNDGLTMNYCRN 1667
            E    +R C  G G+SY+GT S T +G  CQ WSSM PH H     +Y    L  NYCRN
Sbjct: 120  ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEH-----SYRGKDLQENYCRN 174

Query: 1668 PDADT-GPWCFTMDPSIRWEYCNLTRCSDTEGTVVAPPTVIQVPSLGPPSEQDCMFGNGK 1726
            P  +  GPWCFT +P +R+E C++ +CS+ E                      CM  NG+
Sbjct: 175  PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVE----------------------CMTCNGE 212

Query: 1727 GYRGKKATTVTGTPCQEWAAQEPHRHSTFIPGTNKWAGLEKNYCRNPDGDINGPWCYTMN 1786
             YRG    T +G  CQ W  Q PHRH  F+P      G + NYCRNPDG    PWCYT++
Sbjct: 213  SYRGLMDHTESGKICQRWDHQTPHRHK-FLPERYPDKGFDDNYCRNPDGQPR-PWCYTLD 270

Query: 1787 PRKLFDYCDIPLC 1799
            P   ++YC I  C
Sbjct: 271  PHTRWEYCAIKTC 283



 Score = 95.1 bits (235), Expect = 6e-19
 Identities = 41/87 (47%), Positives = 51/87 (58%), Gaps = 2/87 (2%)

Query: 19  PEQSHVVQDCYHGDGQSYRGTYSTTVTGRTCQAWSSMTPHQHNRTTENYPNAGLIMNYCR 78
           P+ S V  +C   +G+SYRG    T +G+ CQ W   TPH+H    E YP+ G   NYCR
Sbjct: 199 PQCSEV--ECMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCR 256

Query: 79  NPDAVAAPYCYTRDPGVRWEYCNLTQC 105
           NPD    P+CYT DP  RWEYC +  C
Sbjct: 257 NPDGQPRPWCYTLDPHTRWEYCAIKTC 283



 Score = 90.9 bits (224), Expect = 1e-17
 Identities = 45/130 (34%), Positives = 65/130 (50%), Gaps = 21/130 (16%)

Query: 1718 QDCMFGNGKGYRGKKATTVTGTPCQEWAAQEPHRHSTFIPGTNKWAGLEKNYCRNPDGDI 1777
            ++C+ G G+ Y+G  + T +G  CQ W++  PH HS       +   L++NYCRNP G+ 
Sbjct: 126  RNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSY------RGKDLQENYCRNPRGEE 179

Query: 1778 NGPWCYTMNPRKLFDYCDIPLCASSSFDCGKPQVEPKKCPGSIVGGCVAHPHS------W 1831
             GPWC+T NP   ++ CDIP C+         +VE   C G    G + H  S      W
Sbjct: 180  GGPWCFTSNPEVRYEVCDIPQCS---------EVECMTCNGESYRGLMDHTESGKICQRW 230

Query: 1832 PWQVSLRTRF 1841
              Q   R +F
Sbjct: 231  DHQTPHRHKF 240


>gi|156938340 transmembrane tryptase preproprotein [Homo sapiens]
          Length = 321

 Score =  177 bits (448), Expect = 1e-43
 Identities = 103/250 (41%), Positives = 133/250 (53%), Gaps = 32/250 (12%)

Query: 1806 CGKPQVEPKKCPGSIVGGCVAHPHSWPWQVSLRTRFGKHFCGGTLISPEWVLTAAHCLKK 1865
            CG+PQV      G IVGG  A   +WPWQ SLR R   H CGG+L+SP+WVLTAAHC   
Sbjct: 26   CGRPQVSD--AGGRIVGGHAAPAGAWPWQASLRLR-RVHVCGGSLLSPQWVLTAAHCFSG 82

Query: 1866 SSRPSSYKVILGAHQEVNLESHVQEIEVSRLFLEP-----TQADIALLKLSRPAVITDKV 1920
            S   S Y+V LG   E+ L  H   +    L   P     T  DIAL++LS P  ++ ++
Sbjct: 83   SLNSSDYQVHLG-ELEITLSPHFSTVRQIILHSSPSGQPGTSGDIALVELSVPVTLSSRI 141

Query: 1921 MPACLPSPDYMVTARTECYITGWGETQGTFGTGL-----LKEAQLLVIENEVCNHY---- 1971
            +P CLP           C++TGWG T+   G  L     L+E ++ V++ E C       
Sbjct: 142  LPVCLPEASDDFCPGIRCWVTGWGYTRE--GEPLPPPYSLREVKVSVVDTETCRRDYPGP 199

Query: 1972 -------KYICAEHLARGT-DSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVY 2023
                     +CA    RG  D+CQ DSGGPLVC     ++  G+ SWG GC RPN+PGVY
Sbjct: 200  GGSILQPDMLCA----RGPGDACQDDSGGPLVCQVNGAWVQAGIVSWGEGCGRPNRPGVY 255

Query: 2024 ARVSRFVTWI 2033
             RV  +V WI
Sbjct: 256  TRVPAYVNWI 265


>gi|13994276 marapsin [Homo sapiens]
          Length = 290

 Score =  173 bits (439), Expect = 1e-42
 Identities = 98/262 (37%), Positives = 138/262 (52%), Gaps = 37/262 (14%)

Query: 1800 ASSSFDCGKPQVEPKKCPGSIVGGCVAHPHSWPWQVSLRTRFGKHFCGGTLISPEWVLTA 1859
            A ++  CG+P++  +     +VGG       WPWQVS++ R G HFCGG+LI+ +WVLTA
Sbjct: 20   AKAATACGRPRMLNR-----MVGGQDTQEGEWPWQVSIQ-RNGSHFCGGSLIAEQWVLTA 73

Query: 1860 AHCLKKSSRPSSYKVILGAHQEVNLESHVQEIEVSRLFLEP------TQADIALLKLSRP 1913
            AHC + +S  S Y+V+LGA Q V    H     V ++   P      + AD+AL++L  P
Sbjct: 74   AHCFRNTSETSLYQVLLGARQLVQPGPHAMYARVRQVESNPLYQGTASSADVALVELEAP 133

Query: 1914 AVITDKVMPACLPSPDYMVTARTECYITGWGETQGTFGTGLLKEAQLL------VIENEV 1967
               T+ ++P CLP P  +      C++TGWG         LL E ++L      +I+   
Sbjct: 134  VPFTNYILPVCLPDPSVIFETGMNCWVTGWGSPSEE---DLLPEPRILQKLAVPIIDTPK 190

Query: 1968 CN-------HYKY---------ICAEHLARGTDSCQGDSGGPLVCFEKDKYILQGVTSWG 2011
            CN        + Y         +CA       D+C+GDSGGPLVC     ++  GV SWG
Sbjct: 191  CNLLYSKDTEFGYQPKTIKNDMLCAGFEEGKKDACKGDSGGPLVCLVGQSWLQAGVISWG 250

Query: 2012 LGCARPNKPGVYARVSRFVTWI 2033
             GCAR N+PGVY RV+    WI
Sbjct: 251  EGCARQNRPGVYIRVTAHHNWI 272


>gi|117956391 protease, serine, 33 [Homo sapiens]
          Length = 280

 Score =  173 bits (438), Expect = 2e-42
 Identities = 93/256 (36%), Positives = 137/256 (53%), Gaps = 35/256 (13%)

Query: 1806 CGKPQVEPKKCPGSIVGGCVAHPHSWPWQVSLRTRFGKHFCGGTLISPEWVLTAAHCLKK 1865
            CG+P++  +     IVGG       WPWQ S++ R G H CGG+LI+P+WVLTAAHC  +
Sbjct: 28   CGQPRMSSR-----IVGGRDGRDGEWPWQASIQHR-GAHVCGGSLIAPQWVLTAAHCFPR 81

Query: 1866 SSRPSSYKVILGAHQEVNLESHVQEIEVSRLFLEP------TQADIALLKLSRPAVITDK 1919
             + P+ Y+V LGA +  +       + V R+ L P       + D+ALL+L RP  ++ +
Sbjct: 82   RALPAEYRVRLGALRLGSTSPRTLSVPVRRVLLPPDYSEDGARGDLALLQLRRPVPLSAR 141

Query: 1920 VMPACLPSPDYMVTARTECYITGWGETQGTFGTGL-----LKEAQLLVIENEVCNHYKYI 1974
            V P CLP P       T C +TGWG  +   G  L     L+  ++ ++++  C+   ++
Sbjct: 142  VQPVCLPVPGARPPPGTPCRVTGWGSLRP--GVPLPEWRPLQGVRVPLLDSRTCDGLYHV 199

Query: 1975 ----------------CAEHLARGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPN 2018
                            CA +     D+CQGDSGGPL C +   ++L GV SWG GCA PN
Sbjct: 200  GADVPQAERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQSGSWVLVGVVSWGKGCALPN 259

Query: 2019 KPGVYARVSRFVTWIE 2034
            +PGVY  V+ +  WI+
Sbjct: 260  RPGVYTSVATYSPWIQ 275


>gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo sapiens]
          Length = 454

 Score =  172 bits (435), Expect = 4e-42
 Identities = 93/236 (39%), Positives = 134/236 (56%), Gaps = 16/236 (6%)

Query: 1820 IVGGCVAHPHSWPWQVSLRTRFGKHFCGGTLISPEWVLTAAHCLKKSSRPSSYKVILGAH 1879
            IVGG ++    WPWQ SL+ + G H CGG++I+P W++TAAHC+     P S+ + +G  
Sbjct: 217  IVGGNMSLLSQWPWQASLQFQ-GYHLCGGSVITPLWIITAAHCVYDLYLPKSWTIQVGLV 275

Query: 1880 QEVN--LESHVQEIEVSRLFLEPTQA--DIALLKLSRPAVITDKVMPACLPSPDYMVTAR 1935
              ++    SH+ E  V     +P +   DIAL+KL+ P    + + P CLP+ +      
Sbjct: 276  SLLDNPAPSHLVEKIVYHSKYKPKRLGNDIALMKLAGPLTFNEMIQPVCLPNSEENFPDG 335

Query: 1936 TECYITGWGETQGTFGTG--LLKEAQLLVIENEVCNHY---------KYICAEHLARGTD 1984
              C+ +GWG T+   G    +L  A + +I N++CNH            +CA +L  G D
Sbjct: 336  KVCWTSGWGATEDGAGDASPVLNHAAVPLISNKICNHRDVYGGIISPSMLCAGYLTGGVD 395

Query: 1985 SCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYARVSRFVTWIEGMMRNN 2040
            SCQGDSGGPLVC E+  + L G TS+G+GCA  NKPGVY RV+ F+ WI   M  +
Sbjct: 396  SCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNKPGVYTRVTSFLDWIHEQMERD 451


>gi|33695155 hepsin [Homo sapiens]
          Length = 417

 Score =  171 bits (432), Expect = 9e-42
 Identities = 117/327 (35%), Positives = 161/327 (49%), Gaps = 40/327 (12%)

Query: 1736 VTGTPCQEWAAQEPHRHSTFIPGTNKWAGLEKNYCRNPDGDINGPWCYTMNPRKLFDYCD 1795
            V G  C+E        HS     T    G    +C +      G   +T    ++   CD
Sbjct: 85   VAGLSCEEMGFLRALTHSELDVRTAGANGTSGFFCVD-----EGRLPHTQRLLEVISVCD 139

Query: 1796 IP---LCASSSFDCGKPQVEPKKCPGSIVGGCVAHPHSWPWQVSLRTRFGKHFCGGTLIS 1852
             P     A+   DCG+ ++   +    IVGG       WPWQVSLR   G H CGG+L+S
Sbjct: 140  CPRGRFLAAICQDCGRRKLPVDR----IVGGRDTSLGRWPWQVSLRYD-GAHLCGGSLLS 194

Query: 1853 PEWVLTAAHCLKKSSRP-SSYKVILGAHQEVN---LESHVQEIEVSRLFL-------EPT 1901
             +WVLTAAHC  + +R  S ++V  GA  + +   L+  VQ +     +L       E  
Sbjct: 195  GDWVLTAAHCFPERNRVLSRWRVFAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEEN 254

Query: 1902 QADIALLKLSRPAVITDKVMPACLPSPDYMVTARTECYITGWGETQGTFG--TGLLKEAQ 1959
              DIAL+ LS P  +T+ + P CLP+    +     C +TGWG TQ  +G   G+L+EA+
Sbjct: 255  SNDIALVHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQ-YYGQQAGVLQEAR 313

Query: 1960 LLVIENEVCN---------HYKYICAEHLARGTDSCQGDSGGPLVCFEK----DKYILQG 2006
            + +I N+VCN           K  CA +   G D+CQGDSGGP VC +      ++ L G
Sbjct: 314  VPIISNDVCNGADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCG 373

Query: 2007 VTSWGLGCARPNKPGVYARVSRFVTWI 2033
            + SWG GCA   KPGVY +VS F  WI
Sbjct: 374  IVSWGTGCALAQKPGVYTKVSDFREWI 400


>gi|4504481 hepsin [Homo sapiens]
          Length = 417

 Score =  171 bits (432), Expect = 9e-42
 Identities = 117/327 (35%), Positives = 161/327 (49%), Gaps = 40/327 (12%)

Query: 1736 VTGTPCQEWAAQEPHRHSTFIPGTNKWAGLEKNYCRNPDGDINGPWCYTMNPRKLFDYCD 1795
            V G  C+E        HS     T    G    +C +      G   +T    ++   CD
Sbjct: 85   VAGLSCEEMGFLRALTHSELDVRTAGANGTSGFFCVD-----EGRLPHTQRLLEVISVCD 139

Query: 1796 IP---LCASSSFDCGKPQVEPKKCPGSIVGGCVAHPHSWPWQVSLRTRFGKHFCGGTLIS 1852
             P     A+   DCG+ ++   +    IVGG       WPWQVSLR   G H CGG+L+S
Sbjct: 140  CPRGRFLAAICQDCGRRKLPVDR----IVGGRDTSLGRWPWQVSLRYD-GAHLCGGSLLS 194

Query: 1853 PEWVLTAAHCLKKSSRP-SSYKVILGAHQEVN---LESHVQEIEVSRLFL-------EPT 1901
             +WVLTAAHC  + +R  S ++V  GA  + +   L+  VQ +     +L       E  
Sbjct: 195  GDWVLTAAHCFPERNRVLSRWRVFAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEEN 254

Query: 1902 QADIALLKLSRPAVITDKVMPACLPSPDYMVTARTECYITGWGETQGTFG--TGLLKEAQ 1959
              DIAL+ LS P  +T+ + P CLP+    +     C +TGWG TQ  +G   G+L+EA+
Sbjct: 255  SNDIALVHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQ-YYGQQAGVLQEAR 313

Query: 1960 LLVIENEVCN---------HYKYICAEHLARGTDSCQGDSGGPLVCFEK----DKYILQG 2006
            + +I N+VCN           K  CA +   G D+CQGDSGGP VC +      ++ L G
Sbjct: 314  VPIISNDVCNGADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCG 373

Query: 2007 VTSWGLGCARPNKPGVYARVSRFVTWI 2033
            + SWG GCA   KPGVY +VS F  WI
Sbjct: 374  IVSWGTGCALAQKPGVYTKVSDFREWI 400


>gi|222537759 plasminogen activator, urokinase isoform 2 [Homo
            sapiens]
          Length = 414

 Score =  169 bits (429), Expect = 2e-41
 Identities = 125/359 (34%), Positives = 160/359 (44%), Gaps = 54/359 (15%)

Query: 1720 CMFGNGKGYRGKKATTVTGTPCQEWAAQ-------EPHRHSTFIPGTNKWAGLEKNYCRN 1772
            C  GNG  YRGK +T   G PC  W +          HR      G  K      NYCRN
Sbjct: 53   CYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSDALQLGLGK-----HNYCRN 107

Query: 1773 PDGDINGPWCYT-MNPRKLFDYCDIPLCASSS----------FDCGKPQVEPKKCPGSIV 1821
            PD     PWCY  +  + L   C +  CA             F CG+  + P+     I+
Sbjct: 108  PDNR-RRPWCYVQVGLKPLVQECMVHDCADGKKPSSPPEELKFQCGQKTLRPRF---KII 163

Query: 1822 GGCVAHPHSWPWQVSL--RTRFGK--HFCGGTLISPEWVLTAAHCLKKSSRPSSYKVILG 1877
            GG      + PW  ++  R R G   + CGG+LISP WV++A HC     +   Y V LG
Sbjct: 164  GGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVYLG 223

Query: 1878 AHQEVNLESHVQEIEVSRLFLEPTQA--------DIALLKL----SRPAVITDKVMPACL 1925
              +  +      + EV  L L    +        DIALLK+     R A  +  +   CL
Sbjct: 224  RSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQTICL 283

Query: 1926 PSPDYMVTARTECYITGWGETQGT--FGTGLLKEAQLLVIENEVCN--HY-------KYI 1974
            PS        T C ITG+G+   T       LK   + +I +  C   HY       K +
Sbjct: 284  PSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKML 343

Query: 1975 CAEHLARGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYARVSRFVTWI 2033
            CA      TDSCQGDSGGPLVC  + +  L G+ SWG GCA  +KPGVY RVS F+ WI
Sbjct: 344  CAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWI 402



 Score = 62.4 bits (150), Expect = 4e-09
 Identities = 29/65 (44%), Positives = 34/65 (52%), Gaps = 3/65 (4%)

Query: 1274 CYHGDGQSYRGSFSTTVTGRTCQSWSSMT---PHWHQRTTEYYPNGGLTRNYCRNPDAEI 1330
            CY G+G  YRG  ST   GR C  W+S T     +H   ++    G    NYCRNPD   
Sbjct: 53   CYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSDALQLGLGKHNYCRNPDNRR 112

Query: 1331 RPWCY 1335
            RPWCY
Sbjct: 113  RPWCY 117



 Score = 61.2 bits (147), Expect = 1e-08
 Identities = 33/68 (48%), Positives = 36/68 (52%), Gaps = 9/68 (13%)

Query: 1388 CYRGDGQSYRGTLSTTITGRTCQSWSS-----MTPHWHRRIPLYYPNAGLTR-NYCRNPD 1441
            CY G+G  YRG  ST   GR C  W+S      T H HR   L     GL + NYCRNPD
Sbjct: 53   CYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSDAL---QLGLGKHNYCRNPD 109

Query: 1442 AEIRPWCY 1449
               RPWCY
Sbjct: 110  NRRRPWCY 117



 Score = 60.8 bits (146), Expect = 1e-08
 Identities = 34/90 (37%), Positives = 46/90 (51%), Gaps = 12/90 (13%)

Query: 1614 RQCYHGNGQSYRGTFSTTVTGRTCQSWSSMTPHRHQRTPENYPNDGLTM-----NYCRNP 1668
            + CY GNG  YRG  ST   GR C  W+S T    Q+T   + +D L +     NYCRNP
Sbjct: 51   KTCYEGNGHFYRGKASTDTMGRPCLPWNSATV--LQQTYHAHRSDALQLGLGKHNYCRNP 108

Query: 1669 DADTGPWCFT---MDPSIRWEYCNLTRCSD 1695
            D    PWC+    + P +  + C +  C+D
Sbjct: 109  DNRRRPWCYVQVGLKPLV--QECMVHDCAD 136



 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 28/65 (43%), Positives = 33/65 (50%), Gaps = 3/65 (4%)

Query: 1168 CYHGDGQSYRGSFSTTVTGRTCQSWSSMT---PHWHQRTTEYYPNGGLTRNYCRNPDAEI 1224
            CY G+G  YRG  ST   GR C  W+S T     +H   ++    G    NYCRNPD   
Sbjct: 53   CYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSDALQLGLGKHNYCRNPDNRR 112

Query: 1225 SPWCY 1229
             PWCY
Sbjct: 113  RPWCY 117



 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 27/65 (41%), Positives = 37/65 (56%), Gaps = 3/65 (4%)

Query: 1502 CYHGDGRSYRGISSTTVTGRTCQSWSS--MIPHWHQRTPENYPNAGL-TENYCRNPDSGK 1558
            CY G+G  YRG +ST   GR C  W+S  ++   +     +    GL   NYCRNPD+ +
Sbjct: 53   CYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSDALQLGLGKHNYCRNPDNRR 112

Query: 1559 QPWCY 1563
            +PWCY
Sbjct: 113  RPWCY 117



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 36/96 (37%), Positives = 46/96 (47%), Gaps = 12/96 (12%)

Query: 826 CYHGNGQSYRGTYSTTVTGRTCQAWSS-----MTPHSHSRTPEYYPNAGLIMNYCRNPDP 880
           CY GNG  YRG  ST   GR C  W+S      T H+H R+       G   NYCRNPD 
Sbjct: 53  CYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAH-RSDALQLGLGK-HNYCRNPDN 110

Query: 881 VAAPYCYTR---DPSVRWEYCNLTQCSDAEGTAVAP 913
              P+CY +    P V  + C +  C+D +  +  P
Sbjct: 111 RRRPWCYVQVGLKPLV--QECMVHDCADGKKPSSPP 144



 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 35/95 (36%), Positives = 47/95 (49%), Gaps = 10/95 (10%)

Query: 142 CYHGNGQSYRGTYSTTVTGRTCQAWSS-----MTPHSHSRTPEYYPNAGLIMNYCRNPDA 196
           CY GNG  YRG  ST   GR C  W+S      T H+H R+       G   NYCRNPD 
Sbjct: 53  CYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAH-RSDALQLGLGK-HNYCRNPDN 110

Query: 197 VAAPYCYTRDPGVR--WEYCNLTQCSDAEGTAVAP 229
              P+CY +  G++   + C +  C+D +  +  P
Sbjct: 111 RRRPWCYVQ-VGLKPLVQECMVHDCADGKKPSSPP 144



 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 35/95 (36%), Positives = 47/95 (49%), Gaps = 10/95 (10%)

Query: 256 CYHGNGQSYRGTYSTTVTGRTCQAWSS-----MTPHSHSRTPEYYPNAGLIMNYCRNPDA 310
           CY GNG  YRG  ST   GR C  W+S      T H+H R+       G   NYCRNPD 
Sbjct: 53  CYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAH-RSDALQLGLGK-HNYCRNPDN 110

Query: 311 VAAPYCYTRDPGVR--WEYCNLTQCSDAEGTAVAP 343
              P+CY +  G++   + C +  C+D +  +  P
Sbjct: 111 RRRPWCYVQ-VGLKPLVQECMVHDCADGKKPSSPP 144



 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 35/95 (36%), Positives = 47/95 (49%), Gaps = 10/95 (10%)

Query: 370 CYHGNGQSYRGTYSTTVTGRTCQAWSS-----MTPHSHSRTPEYYPNAGLIMNYCRNPDA 424
           CY GNG  YRG  ST   GR C  W+S      T H+H R+       G   NYCRNPD 
Sbjct: 53  CYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAH-RSDALQLGLGK-HNYCRNPDN 110

Query: 425 VAAPYCYTRDPGVR--WEYCNLTQCSDAEGTAVAP 457
              P+CY +  G++   + C +  C+D +  +  P
Sbjct: 111 RRRPWCYVQ-VGLKPLVQECMVHDCADGKKPSSPP 144



 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 35/95 (36%), Positives = 47/95 (49%), Gaps = 10/95 (10%)

Query: 484 CYHGNGQSYRGTYSTTVTGRTCQAWSS-----MTPHSHSRTPEYYPNAGLIMNYCRNPDA 538
           CY GNG  YRG  ST   GR C  W+S      T H+H R+       G   NYCRNPD 
Sbjct: 53  CYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAH-RSDALQLGLGK-HNYCRNPDN 110

Query: 539 VAAPYCYTRDPGVR--WEYCNLTQCSDAEGTAVAP 571
              P+CY +  G++   + C +  C+D +  +  P
Sbjct: 111 RRRPWCYVQ-VGLKPLVQECMVHDCADGKKPSSPP 144



 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 35/95 (36%), Positives = 47/95 (49%), Gaps = 10/95 (10%)

Query: 598 CYHGNGQSYRGTYSTTVTGRTCQAWSS-----MTPHSHSRTPEYYPNAGLIMNYCRNPDA 652
           CY GNG  YRG  ST   GR C  W+S      T H+H R+       G   NYCRNPD 
Sbjct: 53  CYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAH-RSDALQLGLGK-HNYCRNPDN 110

Query: 653 VAAPYCYTRDPGVR--WEYCNLTQCSDAEGTAVAP 685
              P+CY +  G++   + C +  C+D +  +  P
Sbjct: 111 RRRPWCYVQ-VGLKPLVQECMVHDCADGKKPSSPP 144



 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 35/95 (36%), Positives = 47/95 (49%), Gaps = 10/95 (10%)

Query: 712 CYHGNGQSYRGTYSTTVTGRTCQAWSS-----MTPHSHSRTPEYYPNAGLIMNYCRNPDA 766
           CY GNG  YRG  ST   GR C  W+S      T H+H R+       G   NYCRNPD 
Sbjct: 53  CYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAH-RSDALQLGLGK-HNYCRNPDN 110

Query: 767 VAAPYCYTRDPGVR--WEYCNLTQCSDAEGTAVAP 799
              P+CY +  G++   + C +  C+D +  +  P
Sbjct: 111 RRRPWCYVQ-VGLKPLVQECMVHDCADGKKPSSPP 144



 Score = 55.1 bits (131), Expect = 7e-07
 Identities = 28/65 (43%), Positives = 31/65 (47%), Gaps = 3/65 (4%)

Query: 1054 CYYHYGQSYRGTYSTTVTGRTCQAWSSMTPHQ---HSRTPENYPNAGLTRNYCRNPDAEI 1110
            CY   G  YRG  ST   GR C  W+S T  Q   H+   +         NYCRNPD   
Sbjct: 53   CYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSDALQLGLGKHNYCRNPDNRR 112

Query: 1111 RPWCY 1115
            RPWCY
Sbjct: 113  RPWCY 117



 Score = 54.7 bits (130), Expect = 9e-07
 Identities = 32/93 (34%), Positives = 44/93 (47%), Gaps = 6/93 (6%)

Query: 28  CYHGDGQSYRGTYSTTVTGRTCQAWSSMTPHQHNRTTENYPNAGLIM---NYCRNPDAVA 84
           CY G+G  YRG  ST   GR C  W+S T  Q            L +   NYCRNPD   
Sbjct: 53  CYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSDALQLGLGKHNYCRNPDNRR 112

Query: 85  APYCYTRDPGVR--WEYCNLTQCSDAEGTAVAP 115
            P+CY +  G++   + C +  C+D +  +  P
Sbjct: 113 RPWCYVQ-VGLKPLVQECMVHDCADGKKPSSPP 144



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 34/90 (37%), Positives = 42/90 (46%), Gaps = 12/90 (13%)

Query: 940  CYHGNGQSYQGTYFITVTGRTCQAWSS-----MTPHSHSRTPAYYPNAGLIKNYCRNPDP 994
            CY GNG  Y+G       GR C  W+S      T H+H R+ A     G   NYCRNPD 
Sbjct: 53   CYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAH-RSDALQLGLGK-HNYCRNPDN 110

Query: 995  VAAPWCYT---TDPSVRWEYCNLTRCSDAE 1021
               PWCY      P V  + C +  C+D +
Sbjct: 111  RRRPWCYVQVGLKPLV--QECMVHDCADGK 138


>gi|4505863 plasminogen activator, urokinase isoform 1 preproprotein
            [Homo sapiens]
          Length = 431

 Score =  169 bits (429), Expect = 2e-41
 Identities = 125/359 (34%), Positives = 160/359 (44%), Gaps = 54/359 (15%)

Query: 1720 CMFGNGKGYRGKKATTVTGTPCQEWAAQ-------EPHRHSTFIPGTNKWAGLEKNYCRN 1772
            C  GNG  YRGK +T   G PC  W +          HR      G  K      NYCRN
Sbjct: 70   CYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSDALQLGLGK-----HNYCRN 124

Query: 1773 PDGDINGPWCYT-MNPRKLFDYCDIPLCASSS----------FDCGKPQVEPKKCPGSIV 1821
            PD     PWCY  +  + L   C +  CA             F CG+  + P+     I+
Sbjct: 125  PDNR-RRPWCYVQVGLKPLVQECMVHDCADGKKPSSPPEELKFQCGQKTLRPRF---KII 180

Query: 1822 GGCVAHPHSWPWQVSL--RTRFGK--HFCGGTLISPEWVLTAAHCLKKSSRPSSYKVILG 1877
            GG      + PW  ++  R R G   + CGG+LISP WV++A HC     +   Y V LG
Sbjct: 181  GGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVYLG 240

Query: 1878 AHQEVNLESHVQEIEVSRLFLEPTQA--------DIALLKL----SRPAVITDKVMPACL 1925
              +  +      + EV  L L    +        DIALLK+     R A  +  +   CL
Sbjct: 241  RSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQTICL 300

Query: 1926 PSPDYMVTARTECYITGWGETQGT--FGTGLLKEAQLLVIENEVCN--HY-------KYI 1974
            PS        T C ITG+G+   T       LK   + +I +  C   HY       K +
Sbjct: 301  PSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKML 360

Query: 1975 CAEHLARGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYARVSRFVTWI 2033
            CA      TDSCQGDSGGPLVC  + +  L G+ SWG GCA  +KPGVY RVS F+ WI
Sbjct: 361  CAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWI 419



 Score = 62.4 bits (150), Expect = 4e-09
 Identities = 29/65 (44%), Positives = 34/65 (52%), Gaps = 3/65 (4%)

Query: 1274 CYHGDGQSYRGSFSTTVTGRTCQSWSSMT---PHWHQRTTEYYPNGGLTRNYCRNPDAEI 1330
            CY G+G  YRG  ST   GR C  W+S T     +H   ++    G    NYCRNPD   
Sbjct: 70   CYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSDALQLGLGKHNYCRNPDNRR 129

Query: 1331 RPWCY 1335
            RPWCY
Sbjct: 130  RPWCY 134



 Score = 61.2 bits (147), Expect = 1e-08
 Identities = 33/68 (48%), Positives = 36/68 (52%), Gaps = 9/68 (13%)

Query: 1388 CYRGDGQSYRGTLSTTITGRTCQSWSS-----MTPHWHRRIPLYYPNAGLTR-NYCRNPD 1441
            CY G+G  YRG  ST   GR C  W+S      T H HR   L     GL + NYCRNPD
Sbjct: 70   CYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSDAL---QLGLGKHNYCRNPD 126

Query: 1442 AEIRPWCY 1449
               RPWCY
Sbjct: 127  NRRRPWCY 134



 Score = 60.8 bits (146), Expect = 1e-08
 Identities = 34/90 (37%), Positives = 46/90 (51%), Gaps = 12/90 (13%)

Query: 1614 RQCYHGNGQSYRGTFSTTVTGRTCQSWSSMTPHRHQRTPENYPNDGLTM-----NYCRNP 1668
            + CY GNG  YRG  ST   GR C  W+S T    Q+T   + +D L +     NYCRNP
Sbjct: 68   KTCYEGNGHFYRGKASTDTMGRPCLPWNSATV--LQQTYHAHRSDALQLGLGKHNYCRNP 125

Query: 1669 DADTGPWCFT---MDPSIRWEYCNLTRCSD 1695
            D    PWC+    + P +  + C +  C+D
Sbjct: 126  DNRRRPWCYVQVGLKPLV--QECMVHDCAD 153



 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 28/65 (43%), Positives = 33/65 (50%), Gaps = 3/65 (4%)

Query: 1168 CYHGDGQSYRGSFSTTVTGRTCQSWSSMT---PHWHQRTTEYYPNGGLTRNYCRNPDAEI 1224
            CY G+G  YRG  ST   GR C  W+S T     +H   ++    G    NYCRNPD   
Sbjct: 70   CYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSDALQLGLGKHNYCRNPDNRR 129

Query: 1225 SPWCY 1229
             PWCY
Sbjct: 130  RPWCY 134



 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 27/65 (41%), Positives = 37/65 (56%), Gaps = 3/65 (4%)

Query: 1502 CYHGDGRSYRGISSTTVTGRTCQSWSS--MIPHWHQRTPENYPNAGL-TENYCRNPDSGK 1558
            CY G+G  YRG +ST   GR C  W+S  ++   +     +    GL   NYCRNPD+ +
Sbjct: 70   CYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSDALQLGLGKHNYCRNPDNRR 129

Query: 1559 QPWCY 1563
            +PWCY
Sbjct: 130  RPWCY 134



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 36/96 (37%), Positives = 46/96 (47%), Gaps = 12/96 (12%)

Query: 826 CYHGNGQSYRGTYSTTVTGRTCQAWSS-----MTPHSHSRTPEYYPNAGLIMNYCRNPDP 880
           CY GNG  YRG  ST   GR C  W+S      T H+H R+       G   NYCRNPD 
Sbjct: 70  CYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAH-RSDALQLGLGK-HNYCRNPDN 127

Query: 881 VAAPYCYTR---DPSVRWEYCNLTQCSDAEGTAVAP 913
              P+CY +    P V  + C +  C+D +  +  P
Sbjct: 128 RRRPWCYVQVGLKPLV--QECMVHDCADGKKPSSPP 161



 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 35/95 (36%), Positives = 47/95 (49%), Gaps = 10/95 (10%)

Query: 142 CYHGNGQSYRGTYSTTVTGRTCQAWSS-----MTPHSHSRTPEYYPNAGLIMNYCRNPDA 196
           CY GNG  YRG  ST   GR C  W+S      T H+H R+       G   NYCRNPD 
Sbjct: 70  CYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAH-RSDALQLGLGK-HNYCRNPDN 127

Query: 197 VAAPYCYTRDPGVR--WEYCNLTQCSDAEGTAVAP 229
              P+CY +  G++   + C +  C+D +  +  P
Sbjct: 128 RRRPWCYVQ-VGLKPLVQECMVHDCADGKKPSSPP 161



 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 35/95 (36%), Positives = 47/95 (49%), Gaps = 10/95 (10%)

Query: 256 CYHGNGQSYRGTYSTTVTGRTCQAWSS-----MTPHSHSRTPEYYPNAGLIMNYCRNPDA 310
           CY GNG  YRG  ST   GR C  W+S      T H+H R+       G   NYCRNPD 
Sbjct: 70  CYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAH-RSDALQLGLGK-HNYCRNPDN 127

Query: 311 VAAPYCYTRDPGVR--WEYCNLTQCSDAEGTAVAP 343
              P+CY +  G++   + C +  C+D +  +  P
Sbjct: 128 RRRPWCYVQ-VGLKPLVQECMVHDCADGKKPSSPP 161



 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 35/95 (36%), Positives = 47/95 (49%), Gaps = 10/95 (10%)

Query: 370 CYHGNGQSYRGTYSTTVTGRTCQAWSS-----MTPHSHSRTPEYYPNAGLIMNYCRNPDA 424
           CY GNG  YRG  ST   GR C  W+S      T H+H R+       G   NYCRNPD 
Sbjct: 70  CYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAH-RSDALQLGLGK-HNYCRNPDN 127

Query: 425 VAAPYCYTRDPGVR--WEYCNLTQCSDAEGTAVAP 457
              P+CY +  G++   + C +  C+D +  +  P
Sbjct: 128 RRRPWCYVQ-VGLKPLVQECMVHDCADGKKPSSPP 161



 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 35/95 (36%), Positives = 47/95 (49%), Gaps = 10/95 (10%)

Query: 484 CYHGNGQSYRGTYSTTVTGRTCQAWSS-----MTPHSHSRTPEYYPNAGLIMNYCRNPDA 538
           CY GNG  YRG  ST   GR C  W+S      T H+H R+       G   NYCRNPD 
Sbjct: 70  CYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAH-RSDALQLGLGK-HNYCRNPDN 127

Query: 539 VAAPYCYTRDPGVR--WEYCNLTQCSDAEGTAVAP 571
              P+CY +  G++   + C +  C+D +  +  P
Sbjct: 128 RRRPWCYVQ-VGLKPLVQECMVHDCADGKKPSSPP 161



 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 35/95 (36%), Positives = 47/95 (49%), Gaps = 10/95 (10%)

Query: 598 CYHGNGQSYRGTYSTTVTGRTCQAWSS-----MTPHSHSRTPEYYPNAGLIMNYCRNPDA 652
           CY GNG  YRG  ST   GR C  W+S      T H+H R+       G   NYCRNPD 
Sbjct: 70  CYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAH-RSDALQLGLGK-HNYCRNPDN 127

Query: 653 VAAPYCYTRDPGVR--WEYCNLTQCSDAEGTAVAP 685
              P+CY +  G++   + C +  C+D +  +  P
Sbjct: 128 RRRPWCYVQ-VGLKPLVQECMVHDCADGKKPSSPP 161



 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 35/95 (36%), Positives = 47/95 (49%), Gaps = 10/95 (10%)

Query: 712 CYHGNGQSYRGTYSTTVTGRTCQAWSS-----MTPHSHSRTPEYYPNAGLIMNYCRNPDA 766
           CY GNG  YRG  ST   GR C  W+S      T H+H R+       G   NYCRNPD 
Sbjct: 70  CYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAH-RSDALQLGLGK-HNYCRNPDN 127

Query: 767 VAAPYCYTRDPGVR--WEYCNLTQCSDAEGTAVAP 799
              P+CY +  G++   + C +  C+D +  +  P
Sbjct: 128 RRRPWCYVQ-VGLKPLVQECMVHDCADGKKPSSPP 161



 Score = 55.1 bits (131), Expect = 7e-07
 Identities = 28/65 (43%), Positives = 31/65 (47%), Gaps = 3/65 (4%)

Query: 1054 CYYHYGQSYRGTYSTTVTGRTCQAWSSMTPHQ---HSRTPENYPNAGLTRNYCRNPDAEI 1110
            CY   G  YRG  ST   GR C  W+S T  Q   H+   +         NYCRNPD   
Sbjct: 70   CYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSDALQLGLGKHNYCRNPDNRR 129

Query: 1111 RPWCY 1115
            RPWCY
Sbjct: 130  RPWCY 134



 Score = 54.7 bits (130), Expect = 9e-07
 Identities = 32/93 (34%), Positives = 44/93 (47%), Gaps = 6/93 (6%)

Query: 28  CYHGDGQSYRGTYSTTVTGRTCQAWSSMTPHQHNRTTENYPNAGLIM---NYCRNPDAVA 84
           CY G+G  YRG  ST   GR C  W+S T  Q            L +   NYCRNPD   
Sbjct: 70  CYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSDALQLGLGKHNYCRNPDNRR 129

Query: 85  APYCYTRDPGVR--WEYCNLTQCSDAEGTAVAP 115
            P+CY +  G++   + C +  C+D +  +  P
Sbjct: 130 RPWCYVQ-VGLKPLVQECMVHDCADGKKPSSPP 161



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 34/90 (37%), Positives = 42/90 (46%), Gaps = 12/90 (13%)

Query: 940  CYHGNGQSYQGTYFITVTGRTCQAWSS-----MTPHSHSRTPAYYPNAGLIKNYCRNPDP 994
            CY GNG  Y+G       GR C  W+S      T H+H R+ A     G   NYCRNPD 
Sbjct: 70   CYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAH-RSDALQLGLGK-HNYCRNPDN 127

Query: 995  VAAPWCYT---TDPSVRWEYCNLTRCSDAE 1021
               PWCY      P V  + C +  C+D +
Sbjct: 128  RRRPWCYVQVGLKPLV--QECMVHDCADGK 155


>gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo
            sapiens]
          Length = 529

 Score =  168 bits (426), Expect = 4e-41
 Identities = 97/236 (41%), Positives = 132/236 (55%), Gaps = 19/236 (8%)

Query: 1820 IVGGCVAHPHSWPWQVSLRTRFGKHFCGGTLISPEWVLTAAHCLKKS-SRPSSYKVILGA 1878
            IVGG  A P +WPWQVSL  +   H CGG++I+PEW++TAAHC++K  + P  +    G 
Sbjct: 293  IVGGESALPGAWPWQVSLHVQ-NVHVCGGSIITPEWIVTAAHCVEKPLNNPWHWTAFAGI 351

Query: 1879 HQEVNLESHVQEIEVSRLFLEPT------QADIALLKLSRPAVITDKVMPACLPSPDYMV 1932
             ++ +   +    +V ++   P         DIAL+KL +P    D V P CLP+P  M+
Sbjct: 352  LRQ-SFMFYGAGYQVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPVCLPNPGMML 410

Query: 1933 TARTECYITGWGETQGTFGTG-LLKEAQLLVIENEVCN-HYKY--------ICAEHLARG 1982
                 C+I+GWG T+    T  +L  A++L+IE + CN  Y Y        ICA  L   
Sbjct: 411  QPEQLCWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSRYVYDNLITPAMICAGFLQGN 470

Query: 1983 TDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYARVSRFVTWIEGMMR 2038
             DSCQGDSGGPLV  + + + L G TSWG GCA+  +PGVY  V  F  WI   MR
Sbjct: 471  VDSCQGDSGGPLVTSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWIYRQMR 526


>gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo
            sapiens]
          Length = 492

 Score =  168 bits (426), Expect = 4e-41
 Identities = 97/236 (41%), Positives = 132/236 (55%), Gaps = 19/236 (8%)

Query: 1820 IVGGCVAHPHSWPWQVSLRTRFGKHFCGGTLISPEWVLTAAHCLKKS-SRPSSYKVILGA 1878
            IVGG  A P +WPWQVSL  +   H CGG++I+PEW++TAAHC++K  + P  +    G 
Sbjct: 256  IVGGESALPGAWPWQVSLHVQ-NVHVCGGSIITPEWIVTAAHCVEKPLNNPWHWTAFAGI 314

Query: 1879 HQEVNLESHVQEIEVSRLFLEPT------QADIALLKLSRPAVITDKVMPACLPSPDYMV 1932
             ++ +   +    +V ++   P         DIAL+KL +P    D V P CLP+P  M+
Sbjct: 315  LRQ-SFMFYGAGYQVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPVCLPNPGMML 373

Query: 1933 TARTECYITGWGETQGTFGTG-LLKEAQLLVIENEVCN-HYKY--------ICAEHLARG 1982
                 C+I+GWG T+    T  +L  A++L+IE + CN  Y Y        ICA  L   
Sbjct: 374  QPEQLCWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSRYVYDNLITPAMICAGFLQGN 433

Query: 1983 TDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYARVSRFVTWIEGMMR 2038
             DSCQGDSGGPLV  + + + L G TSWG GCA+  +PGVY  V  F  WI   MR
Sbjct: 434  VDSCQGDSGGPLVTSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWIYRQMR 489


>gi|118498341 chymotrypsin B1 [Homo sapiens]
          Length = 263

 Score =  167 bits (424), Expect = 7e-41
 Identities = 99/255 (38%), Positives = 139/255 (54%), Gaps = 22/255 (8%)

Query: 1802 SSFDCGKPQVEPKKCPGS-IVGGCVAHPHSWPWQVSLRTRFGKHFCGGTLISPEWVLTAA 1860
            ++F CG P + P     S IV G  A P SWPWQVSL+ + G HFCGG+LIS +WV+TAA
Sbjct: 15   AAFGCGVPAIHPVLSGLSRIVNGEDAVPGSWPWQVSLQDKTGFHFCGGSLISEDWVVTAA 74

Query: 1861 HCLKKSSRPSSYKVILGAHQEVNLESHVQEIEVSRLFLEP------TQADIALLKLSRPA 1914
            HC  ++S      V+ G   + + E ++Q ++++++F  P         DI LLKL+ PA
Sbjct: 75   HCGVRTSD----VVVAGEFDQGSDEENIQVLKIAKVFKNPKFSILTVNNDITLLKLATPA 130

Query: 1915 VITDKVMPACLPSPDYMVTARTECYITGWGETQ--GTFGTGLLKEAQLLVIENEVCNHY- 1971
              +  V   CLPS D    A T C  TGWG+T+         L++A L ++ N  C    
Sbjct: 131  RFSQTVSAVCLPSADDDFPAGTLCATTGWGKTKYNANKTPDKLQQAALPLLSNAECKKSW 190

Query: 1972 ------KYICAEHLARGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYAR 2025
                    ICA   A G  SC GDSGGPLVC +   + L G+ SWG      + PGVYAR
Sbjct: 191  GRRITDVMICAG--ASGVSSCMGDSGGPLVCQKDGAWTLVGIVSWGSDTCSTSSPGVYAR 248

Query: 2026 VSRFVTWIEGMMRNN 2040
            V++ + W++ ++  N
Sbjct: 249  VTKLIPWVQKILAAN 263


>gi|21614531 testisin isoform 2 [Homo sapiens]
          Length = 312

 Score =  167 bits (424), Expect = 7e-41
 Identities = 99/263 (37%), Positives = 137/263 (52%), Gaps = 31/263 (11%)

Query: 1800 ASSSFDCGKPQVEPKKCPGSIVGGCVAHPHSWPWQVSLRTRFGKHFCGGTLISPEWVLTA 1859
            A  S  CG+  +  +     IVGG  A    WPWQ SLR  +  H CG +L+S  W LTA
Sbjct: 27   APLSGPCGRRVITSR-----IVGGEDAELGRWPWQGSLRL-WDSHVCGVSLLSHRWALTA 80

Query: 1860 AHCLKKS-SRPSSYKVILGAHQEV----NLESHVQEIEVSRLFLEP-----TQADIALLK 1909
            AHC +   S PS + V  G    +    +L+++     VS ++L P     +  DIAL+K
Sbjct: 81   AHCFETDLSDPSGWMVQFGQLTSMPSFWSLQAYYTRYFVSNIYLSPRYLGNSPYDIALVK 140

Query: 1910 LSRPAVITDKVMPACLPSPDYMVTARTECYITGWG---ETQGTFGTGLLKEAQLLVIENE 1966
            LS P   T  + P CL +  +    RT+C++TGWG   E +       L+E Q+ +I N 
Sbjct: 141  LSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNS 200

Query: 1967 VCNHY--KY----------ICAEHLARGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGC 2014
            +CNH   KY          +CA +   G D+C GDSGGPL C +   +   GV SWG+GC
Sbjct: 201  MCNHLFLKYSFRKDIFGDMVCAGNAQGGKDACFGDSGGPLACNKNGLWYQIGVVSWGVGC 260

Query: 2015 ARPNKPGVYARVSRFVTWIEGMM 2037
             RPN+PGVY  +S    WI+ +M
Sbjct: 261  GRPNRPGVYTNISHHFEWIQKLM 283


>gi|5803197 testisin isoform 1 [Homo sapiens]
          Length = 314

 Score =  166 bits (420), Expect = 2e-40
 Identities = 99/265 (37%), Positives = 137/265 (51%), Gaps = 33/265 (12%)

Query: 1800 ASSSFDCGKPQVEPKKCPGSIVGGCVAHPHSWPWQVSLRTRFGKHFCGGTLISPEWVLTA 1859
            A  S  CG+  +  +     IVGG  A    WPWQ SLR  +  H CG +L+S  W LTA
Sbjct: 27   APLSGPCGRRVITSR-----IVGGEDAELGRWPWQGSLRL-WDSHVCGVSLLSHRWALTA 80

Query: 1860 AHCLKKSSR---PSSYKVILGAHQEV----NLESHVQEIEVSRLFLEP-----TQADIAL 1907
            AHC +  S    PS + V  G    +    +L+++     VS ++L P     +  DIAL
Sbjct: 81   AHCFETYSDLSDPSGWMVQFGQLTSMPSFWSLQAYYTRYFVSNIYLSPRYLGNSPYDIAL 140

Query: 1908 LKLSRPAVITDKVMPACLPSPDYMVTARTECYITGWG---ETQGTFGTGLLKEAQLLVIE 1964
            +KLS P   T  + P CL +  +    RT+C++TGWG   E +       L+E Q+ +I 
Sbjct: 141  VKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIIN 200

Query: 1965 NEVCNHY--KY----------ICAEHLARGTDSCQGDSGGPLVCFEKDKYILQGVTSWGL 2012
            N +CNH   KY          +CA +   G D+C GDSGGPL C +   +   GV SWG+
Sbjct: 201  NSMCNHLFLKYSFRKDIFGDMVCAGNAQGGKDACFGDSGGPLACNKNGLWYQIGVVSWGV 260

Query: 2013 GCARPNKPGVYARVSRFVTWIEGMM 2037
            GC RPN+PGVY  +S    WI+ +M
Sbjct: 261  GCGRPNRPGVYTNISHHFEWIQKLM 285


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.130    0.435 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 102,520,483
Number of Sequences: 37866
Number of extensions: 5807663
Number of successful extensions: 23612
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 178
Number of HSP's successfully gapped in prelim test: 40
Number of HSP's that attempted gapping in prelim test: 20413
Number of HSP's gapped (non-prelim): 1408
length of query: 2040
length of database: 18,247,518
effective HSP length: 118
effective length of query: 1922
effective length of database: 13,779,330
effective search space: 26483872260
effective search space used: 26483872260
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 70 (31.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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