Guide to the Human Genome
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Search of human proteins with 116284404

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|116284404 cell recognition protein CASPR4 isoform 1 [Homo
sapiens]
         (1308 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|116284404 cell recognition protein CASPR4 isoform 1 [Homo sap...  2679   0.0  
gi|148664242 cell recognition protein CASPR4 isoform 2 [Homo sap...  2504   0.0  
gi|47519929 cell recognition molecule CASPR3 [Homo sapiens]          1861   0.0  
gi|239743754 PREDICTED: hypothetical protein LOC389722 isoform 1...  1845   0.0  
gi|18640734 contactin associated protein-like 5 [Homo sapiens]       1595   0.0  
gi|239743756 PREDICTED: hypothetical protein LOC389722 isoform 2...  1378   0.0  
gi|7662350 cell recognition molecule Caspr2 precursor [Homo sapi...  1286   0.0  
gi|4505463 contactin associated protein 1 precursor [Homo sapiens]    931   0.0  
gi|239743797 PREDICTED: similar to cell recognition molecule CAS...   740   0.0  
gi|239743729 PREDICTED: similar to contactin associated protein-...   551   e-156
gi|169184330 PREDICTED: novel protein similar to contactin assoc...   336   1e-91
gi|239758135 PREDICTED: similar to cell recognition molecule CAS...   193   1e-48
gi|21166380 neurexin 2 isoform alpha-2 precursor [Homo sapiens]       138   3e-32
gi|14211536 neurexin 2 isoform alpha-1 precursor [Homo sapiens]       137   5e-32
gi|14149613 neurexin 1 isoform alpha1 precursor [Homo sapiens]        134   4e-31
gi|208609951 neurexin 1 isoform alpha2 precursor [Homo sapiens]       132   2e-30
gi|21070969 neurexin 3 isoform 1 precursor [Homo sapiens]             125   2e-28
gi|239752499 PREDICTED: similar to cell recognition molecule Cas...   107   6e-23
gi|105990535 coagulation factor V precursor [Homo sapiens]             86   2e-16
gi|54873613 agrin [Homo sapiens]                                       82   3e-15
gi|167830475 milk fat globule-EGF factor 8 protein isoform a [Ho...    81   7e-15
gi|10518506 coagulation factor VIII isoform b precursor [Homo sa...    80   1e-14
gi|4503647 coagulation factor VIII isoform a precursor [Homo sap...    80   1e-14
gi|54792129 discoidin, CUB and LCCL domain containing 2 [Homo sa...    80   2e-14
gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens]            79   2e-14
gi|62420886 discoidin domain receptor family, member 2 precursor...    75   5e-13
gi|62420884 discoidin domain receptor family, member 2 precursor...    75   5e-13
gi|38788416 laminin, alpha 1 precursor [Homo sapiens]                  74   7e-13
gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo...    74   1e-12
gi|33469935 EGF-like, fibronectin type III and laminin G domains...    74   1e-12

>gi|116284404 cell recognition protein CASPR4 isoform 1 [Homo sapiens]
          Length = 1308

 Score = 2679 bits (6944), Expect = 0.0
 Identities = 1308/1308 (100%), Positives = 1308/1308 (100%)

Query: 1    MGSVTGAVLKTLLLLSTQNWNRVEAGNSYDCDDPLVSALPQASFSSSSELSSSHGPGFAR 60
            MGSVTGAVLKTLLLLSTQNWNRVEAGNSYDCDDPLVSALPQASFSSSSELSSSHGPGFAR
Sbjct: 1    MGSVTGAVLKTLLLLSTQNWNRVEAGNSYDCDDPLVSALPQASFSSSSELSSSHGPGFAR 60

Query: 61   LNRRDGAGGWSPLVSNKYQWLQIDLGERMEVTAVATQGGYGSSNWVTSYLLMFSDSGWNW 120
            LNRRDGAGGWSPLVSNKYQWLQIDLGERMEVTAVATQGGYGSSNWVTSYLLMFSDSGWNW
Sbjct: 61   LNRRDGAGGWSPLVSNKYQWLQIDLGERMEVTAVATQGGYGSSNWVTSYLLMFSDSGWNW 120

Query: 121  KQYRQEDSIWGFSGNANADSVVYYRLQPSIKARFLRFIPLEWNPKGRIGMRIEVFGCAYR 180
            KQYRQEDSIWGFSGNANADSVVYYRLQPSIKARFLRFIPLEWNPKGRIGMRIEVFGCAYR
Sbjct: 121  KQYRQEDSIWGFSGNANADSVVYYRLQPSIKARFLRFIPLEWNPKGRIGMRIEVFGCAYR 180

Query: 181  SEVVDLDGKSSLLYRFDQKSLSPIKDIISLKFKTMQSDGILLHREGPNGDHITLQLRRAR 240
            SEVVDLDGKSSLLYRFDQKSLSPIKDIISLKFKTMQSDGILLHREGPNGDHITLQLRRAR
Sbjct: 181  SEVVDLDGKSSLLYRFDQKSLSPIKDIISLKFKTMQSDGILLHREGPNGDHITLQLRRAR 240

Query: 241  LFLLINSGEAKLPSTSTLVNLTLGSLLDDQHWHSVLIQRLGKQVNFTVDEHRHHFHARGE 300
            LFLLINSGEAKLPSTSTLVNLTLGSLLDDQHWHSVLIQRLGKQVNFTVDEHRHHFHARGE
Sbjct: 241  LFLLINSGEAKLPSTSTLVNLTLGSLLDDQHWHSVLIQRLGKQVNFTVDEHRHHFHARGE 300

Query: 301  FNLMNLDYEISFGGIPAPGKSVSFPHRNFHGCLENLYYNGVDIIDLAKQQKPQIIAMGNV 360
            FNLMNLDYEISFGGIPAPGKSVSFPHRNFHGCLENLYYNGVDIIDLAKQQKPQIIAMGNV
Sbjct: 301  FNLMNLDYEISFGGIPAPGKSVSFPHRNFHGCLENLYYNGVDIIDLAKQQKPQIIAMGNV 360

Query: 361  SFSCSQPQSMPVTFLSSRSYLALPDFSGEEEVSATFQFRTWNKAGLLLFSELQLISGGIL 420
            SFSCSQPQSMPVTFLSSRSYLALPDFSGEEEVSATFQFRTWNKAGLLLFSELQLISGGIL
Sbjct: 361  SFSCSQPQSMPVTFLSSRSYLALPDFSGEEEVSATFQFRTWNKAGLLLFSELQLISGGIL 420

Query: 421  LFLSDGKLKSNLYQPGKLPSDITAGVELNDGQWHSVSLSAKKNHLSVAVDGQMASAAPLL 480
            LFLSDGKLKSNLYQPGKLPSDITAGVELNDGQWHSVSLSAKKNHLSVAVDGQMASAAPLL
Sbjct: 421  LFLSDGKLKSNLYQPGKLPSDITAGVELNDGQWHSVSLSAKKNHLSVAVDGQMASAAPLL 480

Query: 481  GPEQIYSGGTYYFGGCPDKSFGSKCKSPLGGFQGCMRLISISGKVVDLISVQQGSLGNFS 540
            GPEQIYSGGTYYFGGCPDKSFGSKCKSPLGGFQGCMRLISISGKVVDLISVQQGSLGNFS
Sbjct: 481  GPEQIYSGGTYYFGGCPDKSFGSKCKSPLGGFQGCMRLISISGKVVDLISVQQGSLGNFS 540

Query: 541  DLQIDSCGISDRCLPNYCEHGGECSQSWSTFHCNCTNTGYRGATCHNSIYEQSCEAYKHR 600
            DLQIDSCGISDRCLPNYCEHGGECSQSWSTFHCNCTNTGYRGATCHNSIYEQSCEAYKHR
Sbjct: 541  DLQIDSCGISDRCLPNYCEHGGECSQSWSTFHCNCTNTGYRGATCHNSIYEQSCEAYKHR 600

Query: 601  GNTSGFYYIDSDGSGPLEPFLLYCNMTETAWTIIQHNGSDLTRVRNTNPENPYAGFFEYV 660
            GNTSGFYYIDSDGSGPLEPFLLYCNMTETAWTIIQHNGSDLTRVRNTNPENPYAGFFEYV
Sbjct: 601  GNTSGFYYIDSDGSGPLEPFLLYCNMTETAWTIIQHNGSDLTRVRNTNPENPYAGFFEYV 660

Query: 661  ASMEQLQATINRAEHCEQEFTYYCKKSRLVNKQDGTPLSWWVGRTNETQTYWGGSSPDLQ 720
            ASMEQLQATINRAEHCEQEFTYYCKKSRLVNKQDGTPLSWWVGRTNETQTYWGGSSPDLQ
Sbjct: 661  ASMEQLQATINRAEHCEQEFTYYCKKSRLVNKQDGTPLSWWVGRTNETQTYWGGSSPDLQ 720

Query: 721  KCTCGLEGNCIDSQYYCNCDADRNEWTNDTGLLAYKEHLPVTKIVITDTGRLHSEAAYKL 780
            KCTCGLEGNCIDSQYYCNCDADRNEWTNDTGLLAYKEHLPVTKIVITDTGRLHSEAAYKL
Sbjct: 721  KCTCGLEGNCIDSQYYCNCDADRNEWTNDTGLLAYKEHLPVTKIVITDTGRLHSEAAYKL 780

Query: 781  GPLLCQGDRSFWNSASFDTEASYLHFPTFHGELSADVSFFFKTTASSGVFLENLGIADFI 840
            GPLLCQGDRSFWNSASFDTEASYLHFPTFHGELSADVSFFFKTTASSGVFLENLGIADFI
Sbjct: 781  GPLLCQGDRSFWNSASFDTEASYLHFPTFHGELSADVSFFFKTTASSGVFLENLGIADFI 840

Query: 841  RIELRSPTVVTFSFDVGNGPFEISVQSPTHFNDNQWHHVRVERNMKEASLQVDQLTPKTQ 900
            RIELRSPTVVTFSFDVGNGPFEISVQSPTHFNDNQWHHVRVERNMKEASLQVDQLTPKTQ
Sbjct: 841  RIELRSPTVVTFSFDVGNGPFEISVQSPTHFNDNQWHHVRVERNMKEASLQVDQLTPKTQ 900

Query: 901  PAPADGHVLLQLNSQLFVGGTATRQRGFLGCIRSLQLNGMTLDLEERAQVTPEVQPGCRG 960
            PAPADGHVLLQLNSQLFVGGTATRQRGFLGCIRSLQLNGMTLDLEERAQVTPEVQPGCRG
Sbjct: 901  PAPADGHVLLQLNSQLFVGGTATRQRGFLGCIRSLQLNGMTLDLEERAQVTPEVQPGCRG 960

Query: 961  HCSSYGKLCRNGGKCRERPIGFFCDCTFSAYTGPFCSNEISAYFGSGSSVIYNFQENYLL 1020
            HCSSYGKLCRNGGKCRERPIGFFCDCTFSAYTGPFCSNEISAYFGSGSSVIYNFQENYLL
Sbjct: 961  HCSSYGKLCRNGGKCRERPIGFFCDCTFSAYTGPFCSNEISAYFGSGSSVIYNFQENYLL 1020

Query: 1021 SKNSSSHAASFHGDMKLSREMIKFSFRTTRTPSLLLFVSSFYKEYLSVIIAKNGSLQIRY 1080
            SKNSSSHAASFHGDMKLSREMIKFSFRTTRTPSLLLFVSSFYKEYLSVIIAKNGSLQIRY
Sbjct: 1021 SKNSSSHAASFHGDMKLSREMIKFSFRTTRTPSLLLFVSSFYKEYLSVIIAKNGSLQIRY 1080

Query: 1081 KLNKYQEPDVVNFDFKNMADGQLHHIMINREEGVVFIEIDDNRRRQVHLSSGTEFSAVKS 1140
            KLNKYQEPDVVNFDFKNMADGQLHHIMINREEGVVFIEIDDNRRRQVHLSSGTEFSAVKS
Sbjct: 1081 KLNKYQEPDVVNFDFKNMADGQLHHIMINREEGVVFIEIDDNRRRQVHLSSGTEFSAVKS 1140

Query: 1141 LVLGRILEHSDVDQDTALAGAQGFTGCLSAVQLSHVAPLKAALHPSHPDPVTVTGHVTES 1200
            LVLGRILEHSDVDQDTALAGAQGFTGCLSAVQLSHVAPLKAALHPSHPDPVTVTGHVTES
Sbjct: 1141 LVLGRILEHSDVDQDTALAGAQGFTGCLSAVQLSHVAPLKAALHPSHPDPVTVTGHVTES 1200

Query: 1201 SCMAQPGTDATSRERTHSFADHSGTIDDREPLANAIKSDSAVIGGLIAVVIFILLCITAI 1260
            SCMAQPGTDATSRERTHSFADHSGTIDDREPLANAIKSDSAVIGGLIAVVIFILLCITAI
Sbjct: 1201 SCMAQPGTDATSRERTHSFADHSGTIDDREPLANAIKSDSAVIGGLIAVVIFILLCITAI 1260

Query: 1261 AVRIYQQKRLYKRSEAKRSENVDSAEAVLKSELNIQNAVNENQKEYFF 1308
            AVRIYQQKRLYKRSEAKRSENVDSAEAVLKSELNIQNAVNENQKEYFF
Sbjct: 1261 AVRIYQQKRLYKRSEAKRSENVDSAEAVLKSELNIQNAVNENQKEYFF 1308


>gi|148664242 cell recognition protein CASPR4 isoform 2 [Homo sapiens]
          Length = 1235

 Score = 2504 bits (6489), Expect = 0.0
 Identities = 1232/1281 (96%), Positives = 1233/1281 (96%), Gaps = 48/1281 (3%)

Query: 28   SYDCDDPLVSALPQASFSSSSELSSSHGPGFARLNRRDGAGGWSPLVSNKYQWLQIDLGE 87
            +YDCDDPLVSALPQASFSSSSELSSSHGPGFARLNRRDGAGGWSPLVSNKYQWLQIDLGE
Sbjct: 3    NYDCDDPLVSALPQASFSSSSELSSSHGPGFARLNRRDGAGGWSPLVSNKYQWLQIDLGE 62

Query: 88   RMEVTAVATQGGYGSSNWVTSYLLMFSDSGWNWKQYRQEDSIWGFSGNANADSVVYYRLQ 147
            RMEVTAVATQGGYGSSNWVTSYLLMFSDSGWNWKQYRQEDSIWGFSGNANADSVVYYRLQ
Sbjct: 63   RMEVTAVATQGGYGSSNWVTSYLLMFSDSGWNWKQYRQEDSIWGFSGNANADSVVYYRLQ 122

Query: 148  PSIKARFLRFIPLEWNPKGRIGMRIEVFGCAYRSEVVDLDGKSSLLYRFDQKSLSPIKDI 207
            PSIKARFLRFIPLEWNPKGRIGMRIEVFGCAYRSEVVDLDGKSSLLYRFDQKSLSPIKDI
Sbjct: 123  PSIKARFLRFIPLEWNPKGRIGMRIEVFGCAYRSEVVDLDGKSSLLYRFDQKSLSPIKDI 182

Query: 208  ISLKFKTMQSDGILLHREGPNGDHITLQLRRARLFLLINSGEAKLPSTSTLVNLTLGSLL 267
            ISLKFKTMQSDGILLHREGPNGDHITLQLRRARLFLLINSGEAKLPSTSTLVNLTLGSLL
Sbjct: 183  ISLKFKTMQSDGILLHREGPNGDHITLQLRRARLFLLINSGEAKLPSTSTLVNLTLGSLL 242

Query: 268  DDQHWHSVLIQRLGKQVNFTVDEHRHHFHARGEFNLMNLDYEISFGGIPAPGKSVSFPHR 327
            DDQHWHSVLIQRLGKQVNFTVDEHRHHFHARGEFNLMNLDYE                  
Sbjct: 243  DDQHWHSVLIQRLGKQVNFTVDEHRHHFHARGEFNLMNLDYE------------------ 284

Query: 328  NFHGCLENLYYNGVDIIDLAKQQKPQIIAMGNVSFSCSQPQSMPVTFLSSRSYLALPDFS 387
                                          GNVSFSCSQPQSMPVTFLSSRSYLALPDFS
Sbjct: 285  ------------------------------GNVSFSCSQPQSMPVTFLSSRSYLALPDFS 314

Query: 388  GEEEVSATFQFRTWNKAGLLLFSELQLISGGILLFLSDGKLKSNLYQPGKLPSDITAGVE 447
            GEEEVSATFQFRTWNKAGLLLFSELQLISGGILLFLSDGKLKSNLYQPGKLPSDITAGVE
Sbjct: 315  GEEEVSATFQFRTWNKAGLLLFSELQLISGGILLFLSDGKLKSNLYQPGKLPSDITAGVE 374

Query: 448  LNDGQWHSVSLSAKKNHLSVAVDGQMASAAPLLGPEQIYSGGTYYFGGCPDKSFGSKCKS 507
            LNDGQWHSVSLSAKKNHLSVAVDGQMASAAPLLGPEQIYSGGTYYFGGCPDKSFGSKCKS
Sbjct: 375  LNDGQWHSVSLSAKKNHLSVAVDGQMASAAPLLGPEQIYSGGTYYFGGCPDKSFGSKCKS 434

Query: 508  PLGGFQGCMRLISISGKVVDLISVQQGSLGNFSDLQIDSCGISDRCLPNYCEHGGECSQS 567
            PLGGFQGCMRLISISGKVVDLISVQQGSLGNFSDLQIDSCGISDRCLPNYCEHGGECSQS
Sbjct: 435  PLGGFQGCMRLISISGKVVDLISVQQGSLGNFSDLQIDSCGISDRCLPNYCEHGGECSQS 494

Query: 568  WSTFHCNCTNTGYRGATCHNSIYEQSCEAYKHRGNTSGFYYIDSDGSGPLEPFLLYCNMT 627
            WSTFHCNCTNTGYRGATCHNSIYEQSCEAYKHRGNTSGFYYIDSDGSGPLEPFLLYCNMT
Sbjct: 495  WSTFHCNCTNTGYRGATCHNSIYEQSCEAYKHRGNTSGFYYIDSDGSGPLEPFLLYCNMT 554

Query: 628  ETAWTIIQHNGSDLTRVRNTNPENPYAGFFEYVASMEQLQATINRAEHCEQEFTYYCKKS 687
            ETAWTIIQHNGSDLTRVRNTNPENPYAGFFEYVASMEQLQATINRAEHCEQEFTYYCKKS
Sbjct: 555  ETAWTIIQHNGSDLTRVRNTNPENPYAGFFEYVASMEQLQATINRAEHCEQEFTYYCKKS 614

Query: 688  RLVNKQDGTPLSWWVGRTNETQTYWGGSSPDLQKCTCGLEGNCIDSQYYCNCDADRNEWT 747
            RLVNKQDGTPLSWWVGRTNETQTYWGGSSPDLQKCTCGLEGNCIDSQYYCNCDADRNEWT
Sbjct: 615  RLVNKQDGTPLSWWVGRTNETQTYWGGSSPDLQKCTCGLEGNCIDSQYYCNCDADRNEWT 674

Query: 748  NDTGLLAYKEHLPVTKIVITDTGRLHSEAAYKLGPLLCQGDRSFWNSASFDTEASYLHFP 807
            NDTGLLAYKEHLPVTKIVITDTGRLHSEAAYKLGPLLCQGDRSFWNSASFDTEASYLHFP
Sbjct: 675  NDTGLLAYKEHLPVTKIVITDTGRLHSEAAYKLGPLLCQGDRSFWNSASFDTEASYLHFP 734

Query: 808  TFHGELSADVSFFFKTTASSGVFLENLGIADFIRIELRSPTVVTFSFDVGNGPFEISVQS 867
            TFHGELSADVSFFFKTTASSGVFLENLGIADFIRIELRSPTVVTFSFDVGNGPFEISVQS
Sbjct: 735  TFHGELSADVSFFFKTTASSGVFLENLGIADFIRIELRSPTVVTFSFDVGNGPFEISVQS 794

Query: 868  PTHFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFVGGTATRQRG 927
            PTHFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFVGGTATRQRG
Sbjct: 795  PTHFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFVGGTATRQRG 854

Query: 928  FLGCIRSLQLNGMTLDLEERAQVTPEVQPGCRGHCSSYGKLCRNGGKCRERPIGFFCDCT 987
            FLGCIRSLQLNGMTLDLEERAQVTPEVQPGCRGHCSSYGKLCRNGGKCRERPIGFFCDCT
Sbjct: 855  FLGCIRSLQLNGMTLDLEERAQVTPEVQPGCRGHCSSYGKLCRNGGKCRERPIGFFCDCT 914

Query: 988  FSAYTGPFCSNEISAYFGSGSSVIYNFQENYLLSKNSSSHAASFHGDMKLSREMIKFSFR 1047
            FSAYTGPFCSNEISAYFGSGSSVIYNFQENYLLSKNSSSHAASFHGDMKLSREMIKFSFR
Sbjct: 915  FSAYTGPFCSNEISAYFGSGSSVIYNFQENYLLSKNSSSHAASFHGDMKLSREMIKFSFR 974

Query: 1048 TTRTPSLLLFVSSFYKEYLSVIIAKNGSLQIRYKLNKYQEPDVVNFDFKNMADGQLHHIM 1107
            TTRTPSLLLFVSSFYKEYLSVIIAKNGSLQIRYKLNKYQEPDVVNFDFKNMADGQLHHIM
Sbjct: 975  TTRTPSLLLFVSSFYKEYLSVIIAKNGSLQIRYKLNKYQEPDVVNFDFKNMADGQLHHIM 1034

Query: 1108 INREEGVVFIEIDDNRRRQVHLSSGTEFSAVKSLVLGRILEHSDVDQDTALAGAQGFTGC 1167
            INREEGVVFIEIDDNRRRQVHLSSGTEFSAVKSLVLGRILEHSDVDQDTALAGAQGFTGC
Sbjct: 1035 INREEGVVFIEIDDNRRRQVHLSSGTEFSAVKSLVLGRILEHSDVDQDTALAGAQGFTGC 1094

Query: 1168 LSAVQLSHVAPLKAALHPSHPDPVTVTGHVTESSCMAQPGTDATSRERTHSFADHSGTID 1227
            LSAVQLSHVAPLKAALHPSHPDPVTVTGHVTESSCMAQPGTDATSRERTHSFADHSGTID
Sbjct: 1095 LSAVQLSHVAPLKAALHPSHPDPVTVTGHVTESSCMAQPGTDATSRERTHSFADHSGTID 1154

Query: 1228 DREPLANAIKSDSAVIGGLIAVVIFILLCITAIAVRIYQQKRLYKRSEAKRSENVDSAEA 1287
            DREPLANAIKSDSAVIGGLIAVVIFILLCITAIAVRIYQQKRLYKRSEAKRSENVDSAEA
Sbjct: 1155 DREPLANAIKSDSAVIGGLIAVVIFILLCITAIAVRIYQQKRLYKRSEAKRSENVDSAEA 1214

Query: 1288 VLKSELNIQNAVNENQKEYFF 1308
            VLKSELNIQNAVNENQKEYFF
Sbjct: 1215 VLKSELNIQNAVNENQKEYFF 1235


>gi|47519929 cell recognition molecule CASPR3 [Homo sapiens]
          Length = 1288

 Score = 1861 bits (4820), Expect = 0.0
 Identities = 906/1286 (70%), Positives = 1049/1286 (81%), Gaps = 8/1286 (0%)

Query: 1    MGSVTGAVLKTLLLLSTQNWNRVEAGNSYDCDDPLVSALPQASFSSSSELSSSHGPGFAR 60
            M SV  AVLK LLLL TQ W+ V AGN  DCD PL SALP++SFSSSSELSSSHGPGF+R
Sbjct: 1    MASVAWAVLKVLLLLPTQTWSPVGAGNPPDCDAPLASALPRSSFSSSSELSSSHGPGFSR 60

Query: 61   LNRRDGAGGWSPLVSNKYQWLQIDLGERMEVTAVATQGGYGSSNWVTSYLLMFSDSGWNW 120
            LNRRDGAGGW+PLVSNKYQWLQIDLGERMEVTAVATQGGYGSS+WVTSYLLMFSD G NW
Sbjct: 61   LNRRDGAGGWTPLVSNKYQWLQIDLGERMEVTAVATQGGYGSSDWVTSYLLMFSDGGRNW 120

Query: 121  KQYRQEDSIWGFSGNANADSVVYYRLQPSIKARFLRFIPLEWNPKGRIGMRIEVFGCAYR 180
            KQYR+E+SIWGF GN NADSVV+YRLQP  +ARFLRF+PL WNP+GRIGMRIEV+GCAY+
Sbjct: 121  KQYRREESIWGFPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGCAYK 180

Query: 181  SEVVDLDGKSSLLYRFDQKSLSPIKDIISLKFKTMQSDGILLHREGPNGDHITLQLRRAR 240
            SEVV  DG+S+LLYR D+K L PI+D+ISLKFK MQS+GILLHREG +G+HITL+L + +
Sbjct: 181  SEVVYFDGQSALLYRLDKKPLKPIRDVISLKFKAMQSNGILLHREGQHGNHITLELIKGK 240

Query: 241  LFLLINSGEAKLPSTSTLVNLTLGSLLDDQHWHSVLIQRLGKQVNFTVDEHRHHFHARGE 300
            L   +NSG AKLPST   V LTLGSLLDDQHWHSVLI+ L  QVNFTVD+H HHF A+G+
Sbjct: 241  LVFFLNSGNAKLPSTIAPVTLTLGSLLDDQHWHSVLIELLDTQVNFTVDKHTHHFQAKGD 300

Query: 301  FNLMNLDYEISFGGIPAPGKSVSFPHRNFHGCLENLYYNGVDIIDLAKQQKPQIIAMGNV 360
             + ++L++EISFGGIP PG+S +F  ++FHGCLENLYYNGVD+ +LAK+ KPQI+ MGNV
Sbjct: 301  SSYLDLNFEISFGGIPTPGRSRAFRRKSFHGCLENLYYNGVDVTELAKKHKPQILMMGNV 360

Query: 361  SFSCSQPQSMPVTFLSSRSYLALPDFSGEEEVSATFQFRTWNKAGLLLFSELQLISGGIL 420
            SFSC QPQ++PVTFLSSRSYLALP  SGE++VS TFQFRTWN+AG LLF EL+  SG  +
Sbjct: 361  SFSCPQPQTVPVTFLSSRSYLALPGNSGEDKVSVTFQFRTWNRAGHLLFGELRRGSGSFV 420

Query: 421  LFLSDGKLKSNLYQPGKLPSDITAGVELNDGQWHSVSLSAKKNHLSVAVDGQMASAAPLL 480
            LFL DGKLK +L+QPG+ P ++TAG  LNDGQWHSVS SAK +H++V VD   A   PL+
Sbjct: 421  LFLKDGKLKLSLFQPGQSPRNVTAGAGLNDGQWHSVSFSAKWSHMNVVVDDDTA-VQPLV 479

Query: 481  GPEQIYSGGTYYFGGCPDKSFGSKCKSPLGGFQGCMRLISISGKVVDLISVQQGSLGNFS 540
                I SG TYYFGGC D S GS CKSPLGGFQGC+RLI+I  K VD I VQQG+LG+F 
Sbjct: 480  AV-LIDSGDTYYFGGCLDNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFR 538

Query: 541  DLQIDSCGISDRCLPNYCEHGGECSQSWSTFHCNCTNTGYRGATCHNSIYEQSCEAYKHR 600
            DLQIDSCGI+DRCLP+YCEHGGECSQSW TF C+C  TGY G TCH+S+YEQSCEA+KHR
Sbjct: 539  DLQIDSCGITDRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHR 598

Query: 601  GNTSGFYYIDSDGSGPLEPFLLYCNMT-ETAWTIIQHNGSDLTRVRNTNPENPYAGF-FE 658
            GN SG YYID+DGSGPL PFL+YCNMT + AWT++QH G D   +R     +P +   F 
Sbjct: 599  GNPSGLYYIDADGSGPLGPFLVYCNMTADAAWTVVQHGGPDAVTLRGAPSGHPRSAVSFA 658

Query: 659  YVASMEQLQATINRAEHCEQEFTYYCKKSRLVNKQDGTPLSWWVGRTNETQTYWGGSSPD 718
            Y A   QL++ +N AE CEQ     C  +R  + +DGTPLSWWVGRTNET T WGGS PD
Sbjct: 659  YAAGAGQLRSAVNLAERCEQRLALRCGTARRPDSRDGTPLSWWVGRTNETHTSWGGSLPD 718

Query: 719  LQKCTCGLEGNCIDSQYYCNCDADRNEWTNDTGLLAYKEHLPVTKIVITDTGRLHSEAAY 778
             QKCTCGLEGNCIDSQYYCNCDA RNEWT+DT +L+ KEHLPVT+IV+TD GR HSEAAY
Sbjct: 719  AQKCTCGLEGNCIDSQYYCNCDAGRNEWTSDTIVLSQKEHLPVTQIVMTDAGRPHSEAAY 778

Query: 779  KLGPLLCQGDRSFWNSASFDTEASYLHFPTFHGELSADVSFFFKTTASSGVFLENLGIAD 838
             LGPLLC+GD+SFWNSASF+TE SYLHFP FHGEL+ADV FFFKTT SSGVF+ENLGI D
Sbjct: 779  TLGPLLCRGDQSFWNSASFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGITD 838

Query: 839  FIRIELRSPTVVTFSFDVGNGPFEISVQSPTHFNDNQWHHVRVERNMKEASLQVDQLTPK 898
            FIRIELR+PT VTFSFDVGNGP E++VQSPT FNDNQWHHVR ERN+K ASLQVDQL  K
Sbjct: 839  FIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQK 898

Query: 899  TQPAPADGHVLLQLNSQLFVGGTATRQRGFLGCIRSLQLNGMTLDLEERAQVTPEVQPGC 958
             QPAPADGHV LQLNSQLF+GGTATRQRGFLGCIRSLQLNG+ LDLEERA VTP V+PGC
Sbjct: 899  MQPAPADGHVRLQLNSQLFIGGTATRQRGFLGCIRSLQLNGVALDLEERATVTPGVEPGC 958

Query: 959  RGHCSSYGKLCRNGGKCRERPIGFFCDCTFSAYTGPFCSNEISAYFGSGSSVIYNFQENY 1018
             GHCS+YG LCRNGG+CRE+  G  CDC FSAY GPFCSNEISAYF +GSS+ Y+FQE+Y
Sbjct: 959  AGHCSTYGHLCRNGGRCREKRRGVTCDCAFSAYDGPFCSNEISAYFATGSSMTYHFQEHY 1018

Query: 1019 LLSKNSSSHAASFHGDMKLSREMIKFSFRTTRTPSLLLFVSSFYKEYLSVIIAKNGSLQI 1078
             LS+NSSS  +S H D+ L+REMI  SFRTTRTPSLLL+VSSFY+EYLSVI+A NGSLQI
Sbjct: 1019 TLSENSSSLVSSLHRDVTLTREMITLSFRTTRTPSLLLYVSSFYEEYLSVILANNGSLQI 1078

Query: 1079 RYKLNKYQEPDVVNFDFKNMADGQLHHIMINREEGVVFIEIDDNRRRQVHLSSGTEFSAV 1138
            RYKL+++Q PD   FDFKNMADGQLH + INREE VV +E++ + ++QV LSSGTEF+AV
Sbjct: 1079 RYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVEVNQSTKKQVILSSGTEFNAV 1138

Query: 1139 KSLVLGRILEHSDVDQDTALAGAQGFTGCLSAVQLSHVAPLKAALHPSHPDPVTVTGHVT 1198
            KSL+LG++LE +  D DT  A   GFTGCLSAV+    APLKAAL PS P  VTV GHV 
Sbjct: 1139 KSLILGKVLEAAGADPDTRRAATSGFTGCLSAVRFGRAAPLKAALRPSGPSRVTVRGHVA 1198

Query: 1199 E-SSCMAQPGTDATSRE---RTHSFADHSGTIDDREPLANAIKSDSAVIGGLIAVVIFIL 1254
              + C A   + + +RE   R    A  SG  D+ EPL NA + DSAVIGG+IAVVIFIL
Sbjct: 1199 PMARCAAGAASGSPARELAPRLAGGAGRSGPADEGEPLVNADRRDSAVIGGVIAVVIFIL 1258

Query: 1255 LCITAIAVRIYQQKRLYKRSEAKRSE 1280
            LCITAIA+RIYQQ++L K +E+K S+
Sbjct: 1259 LCITAIAIRIYQQRKLRKENESKVSK 1284


>gi|239743754 PREDICTED: hypothetical protein LOC389722 isoform 1
            [Homo sapiens]
          Length = 1288

 Score = 1845 bits (4779), Expect = 0.0
 Identities = 898/1286 (69%), Positives = 1048/1286 (81%), Gaps = 8/1286 (0%)

Query: 1    MGSVTGAVLKTLLLLSTQNWNRVEAGNSYDCDDPLVSALPQASFSSSSELSSSHGPGFAR 60
            M SV  AVLK LLLL TQ W+ V AGN  DCD PL SALP++SFSSSSELSSSHGPGF+R
Sbjct: 1    MASVAWAVLKVLLLLPTQTWSPVGAGNPPDCDSPLASALPRSSFSSSSELSSSHGPGFSR 60

Query: 61   LNRRDGAGGWSPLVSNKYQWLQIDLGERMEVTAVATQGGYGSSNWVTSYLLMFSDSGWNW 120
            LNRRDGAGGW+PLVSNKYQWLQIDLGERMEVTAVATQGGYGSS+WVTSYLLMFSD G NW
Sbjct: 61   LNRRDGAGGWTPLVSNKYQWLQIDLGERMEVTAVATQGGYGSSDWVTSYLLMFSDGGRNW 120

Query: 121  KQYRQEDSIWGFSGNANADSVVYYRLQPSIKARFLRFIPLEWNPKGRIGMRIEVFGCAYR 180
            KQYR+E+SIWGF GN NADSVV+YRLQP  +ARFLRF+PL WNP+GRIGMRIEV+GCAY+
Sbjct: 121  KQYRREESIWGFPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGCAYK 180

Query: 181  SEVVDLDGKSSLLYRFDQKSLSPIKDIISLKFKTMQSDGILLHREGPNGDHITLQLRRAR 240
            SEVV  DG+S+LLY  D+K L PI+D+ISLKFK MQS+GILLHREG +G+HITL+L + +
Sbjct: 181  SEVVYFDGQSALLYTLDKKPLKPIRDVISLKFKAMQSNGILLHREGQHGNHITLELIKGK 240

Query: 241  LFLLINSGEAKLPSTSTLVNLTLGSLLDDQHWHSVLIQRLGKQVNFTVDEHRHHFHARGE 300
            L   +NSG AKLPST   V LTLGSLLDDQHWHSVLI+ L  QVNFTVD+H HHF A+G+
Sbjct: 241  LVFFLNSGNAKLPSTIAPVTLTLGSLLDDQHWHSVLIELLDTQVNFTVDKHTHHFQAKGD 300

Query: 301  FNLMNLDYEISFGGIPAPGKSVSFPHRNFHGCLENLYYNGVDIIDLAKQQKPQIIAMGNV 360
             + ++L++EISFGGI +PG+S +F  ++FHGCLENLYYNGVD+ +LAK+ KPQI+ MGNV
Sbjct: 301  SSNLDLNFEISFGGILSPGRSRAFTRKSFHGCLENLYYNGVDVTELAKKHKPQILMMGNV 360

Query: 361  SFSCSQPQSMPVTFLSSRSYLALPDFSGEEEVSATFQFRTWNKAGLLLFSELQLISGGIL 420
            SFSC QPQ++PVTFLSSRSYLALP  SGE++VS TFQFRTWN+AG LLF ELQ  SG  +
Sbjct: 361  SFSCPQPQTVPVTFLSSRSYLALPGNSGEDKVSVTFQFRTWNRAGHLLFGELQRGSGSFV 420

Query: 421  LFLSDGKLKSNLYQPGKLPSDITAGVELNDGQWHSVSLSAKKNHLSVAVDGQMASAAPLL 480
            LFL DGKLK +L+Q G+ P ++TAG  LNDGQWHSVS SAK +H++V VD   A   PL+
Sbjct: 421  LFLKDGKLKLSLFQAGQSPRNVTAGAGLNDGQWHSVSFSAKWSHMNVVVDDDTA-VQPLV 479

Query: 481  GPEQIYSGGTYYFGGCPDKSFGSKCKSPLGGFQGCMRLISISGKVVDLISVQQGSLGNFS 540
                I SG TYYFGGC   S GS CKSPLGGFQGC+RLI+I  K VD I VQQG+LG+F 
Sbjct: 480  AV-LIDSGDTYYFGGCLGNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFR 538

Query: 541  DLQIDSCGISDRCLPNYCEHGGECSQSWSTFHCNCTNTGYRGATCHNSIYEQSCEAYKHR 600
            DLQIDSCGI+DRCLP+YCEHGGECSQSW TF C+C  TGY G TCH+S+YEQSCEA+KHR
Sbjct: 539  DLQIDSCGITDRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHR 598

Query: 601  GNTSGFYYIDSDGSGPLEPFLLYCNMT-ETAWTIIQHNGSDLTRVRNTNPENPYAGF-FE 658
            GN SG YYID+DGSGPL PFL+YCNMT ++AWT+++H G D   +R     +P +   F 
Sbjct: 599  GNPSGLYYIDADGSGPLGPFLVYCNMTADSAWTVVRHGGPDAVTLRGAPSGHPLSAVSFA 658

Query: 659  YVASMEQLQATINRAEHCEQEFTYYCKKSRLVNKQDGTPLSWWVGRTNETQTYWGGSSPD 718
            Y A   QL+A +N AE CEQ     C  +R  + +DGTPLSWWVGRTNET T WGGS PD
Sbjct: 659  YAAGAGQLRAAVNLAERCEQRLALRCGTARRPDSRDGTPLSWWVGRTNETHTSWGGSLPD 718

Query: 719  LQKCTCGLEGNCIDSQYYCNCDADRNEWTNDTGLLAYKEHLPVTKIVITDTGRLHSEAAY 778
             QKCTCGLEGNCIDSQYYCNCDA +NEWT+DT +L+ KEHLPVT+IV+TDTG+ HSEA Y
Sbjct: 719  AQKCTCGLEGNCIDSQYYCNCDAGQNEWTSDTIVLSQKEHLPVTQIVMTDTGQPHSEADY 778

Query: 779  KLGPLLCQGDRSFWNSASFDTEASYLHFPTFHGELSADVSFFFKTTASSGVFLENLGIAD 838
             LGPLLC+GD+SFWNSASF+TE SYLHFP FHGEL+ADV FFFKTT SSGVF+ENLGI D
Sbjct: 779  TLGPLLCRGDKSFWNSASFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGITD 838

Query: 839  FIRIELRSPTVVTFSFDVGNGPFEISVQSPTHFNDNQWHHVRVERNMKEASLQVDQLTPK 898
            FIRIELR+PT VTFSFDVGNGP E++VQSPT FNDNQWHHVR ERN+K ASLQVDQL  K
Sbjct: 839  FIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQK 898

Query: 899  TQPAPADGHVLLQLNSQLFVGGTATRQRGFLGCIRSLQLNGMTLDLEERAQVTPEVQPGC 958
             QPAPADGHV LQLNSQLF+GGTATRQRGFLGCIRSLQLNG+ LDLEERA VTP V+PGC
Sbjct: 899  MQPAPADGHVRLQLNSQLFIGGTATRQRGFLGCIRSLQLNGVALDLEERATVTPGVEPGC 958

Query: 959  RGHCSSYGKLCRNGGKCRERPIGFFCDCTFSAYTGPFCSNEISAYFGSGSSVIYNFQENY 1018
             GHCS+YG LCRNGG+CRE+  G  CDC FSAY GPFCSNEISAYF +GSS+ Y+FQE+Y
Sbjct: 959  AGHCSTYGHLCRNGGRCREKRRGVTCDCAFSAYDGPFCSNEISAYFATGSSMTYHFQEHY 1018

Query: 1019 LLSKNSSSHAASFHGDMKLSREMIKFSFRTTRTPSLLLFVSSFYKEYLSVIIAKNGSLQI 1078
             LS+NSSS  +S + D+ L+REMI  SFRTTR+PSLLL+VSSFY+EYLSVI+A NGSLQI
Sbjct: 1019 TLSENSSSLVSSLYRDVTLTREMITLSFRTTRSPSLLLYVSSFYEEYLSVILANNGSLQI 1078

Query: 1079 RYKLNKYQEPDVVNFDFKNMADGQLHHIMINREEGVVFIEIDDNRRRQVHLSSGTEFSAV 1138
            RYKL+++Q PD   FDFKNMADGQLH + INREE VV +E++ + ++QV LSSGTEF+AV
Sbjct: 1079 RYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVEVNQSAKKQVILSSGTEFNAV 1138

Query: 1139 KSLVLGRILEHSDVDQDTALAGAQGFTGCLSAVQLSHVAPLKAALHPSHPDPVTVTGHVT 1198
            KSL+LG++LE +  D DT  A   GFTGCLSAV+    APLKAAL PS P  VTV GHV 
Sbjct: 1139 KSLILGKVLEAAGADPDTRRAATSGFTGCLSAVRFGRAAPLKAALRPSGPSRVTVRGHVA 1198

Query: 1199 E-SSCMAQPGTDATSRE---RTHSFADHSGTIDDREPLANAIKSDSAVIGGLIAVVIFIL 1254
              + C A   + + +RE   R    A  SG +D+ EPL NA + DSAV+GG+IAVVIFIL
Sbjct: 1199 PMARCAAGAASGSPARELAPRLAGGAGRSGPVDEGEPLVNADRRDSAVMGGVIAVVIFIL 1258

Query: 1255 LCITAIAVRIYQQKRLYKRSEAKRSE 1280
            LCITAIA+RIYQQ++L K +E+K S+
Sbjct: 1259 LCITAIAIRIYQQRKLRKENESKVSK 1284


>gi|18640734 contactin associated protein-like 5 [Homo sapiens]
          Length = 1306

 Score = 1595 bits (4130), Expect = 0.0
 Identities = 762/1299 (58%), Positives = 982/1299 (75%), Gaps = 7/1299 (0%)

Query: 12   LLLLSTQNWNRVEAGNSYDCDDPLVSALPQASFSSSSELSSSHGPGFARLNRRDGAGGWS 71
            L LL +  W+      +Y+CDDPL S L   +FSSSS+L+ +H P  A+LN R G GGWS
Sbjct: 11   LTLLFSGLWHLGLTATNYNCDDPLASLLSPMAFSSSSDLTGTHSP--AQLNWRVGTGGWS 68

Query: 72   PLVSNKYQWLQIDLGERMEVTAVATQGGYGSSNWVTSYLLMFSDSGWNWKQYRQEDSIWG 131
            P  SN  QWLQ+DLG R+E+TAVATQG YGSS+WVTSY LMFSD+G NWKQY+QEDSIW 
Sbjct: 69   PADSNAQQWLQMDLGNRVEITAVATQGRYGSSDWVTSYSLMFSDTGRNWKQYKQEDSIWT 128

Query: 132  FSGNANADSVVYYRLQPSIKARFLRFIPLEWNPKGRIGMRIEVFGCAYRSEVVDLDGKSS 191
            F+GN NADSVV+++L  S++ARF+RF+PLEWNP G+IGMR+EV+GC+Y+S+V D DG+SS
Sbjct: 129  FAGNMNADSVVHHKLLHSVRARFVRFVPLEWNPSGKIGMRVEVYGCSYKSDVADFDGRSS 188

Query: 192  LLYRFDQKSLSPIKDIISLKFKTMQSDGILLHREGPNGDHITLQLRRARLFLLINSGEAK 251
            LLYRF+QK +S +KD+ISLKFK+MQ DG+L H EG  GDHITL+L++ RL L +N G++K
Sbjct: 189  LLYRFNQKLMSTLKDVISLKFKSMQGDGVLFHGEGQRGDHITLELQKGRLALHLNLGDSK 248

Query: 252  LPSTSTLVNLTLGSLLDDQHWHSVLIQRLGKQVNFTVDEHRHHFHARGEFNLMNLDYEIS 311
               +S+L + TLGSLLDDQHWHSVLI+R+GKQVNFTVD+H  HF  +GE + +++DYE+S
Sbjct: 249  ARLSSSLPSATLGSLLDDQHWHSVLIERVGKQVNFTVDKHTQHFRTKGETDALDIDYELS 308

Query: 312  FGGIPAPGKSVSFPHRNFHGCLENLYYNGVDIIDLAKQQKPQIIAMGNVSFSCSQPQSMP 371
            FGGIP PGK  +F  +NFHGC+ENLYYNGV+IIDLAK++K QI   GNV+FSCS+PQ +P
Sbjct: 309  FGGIPVPGKPGTFLKKNFHGCIENLYYNGVNIIDLAKRRKHQIYT-GNVTFSCSEPQIVP 367

Query: 372  VTFL-SSRSYLALPDFSGEEEVSATFQFRTWNKAGLLLFSELQLISGGILLFLSDGKLKS 430
            +TF+ SS SYL LP     + +S +FQFRTWNK GLLL +EL   SG +LL L  G L+ 
Sbjct: 368  ITFVNSSGSYLLLPGTPQIDGLSVSFQFRTWNKDGLLLSTELSEGSGTLLLSLEGGILRL 427

Query: 431  NLYQPGKLPSDITAGVELNDGQWHSVSLSAKKNHLSVAVDGQMASAAPLLGPEQIYSGGT 490
             + +  +  ++I  G  LNDG WHSVS++A++N +++ +D + A  AP     QIYSG +
Sbjct: 428  VIQKMTERVAEILTGSNLNDGLWHSVSINARRNRITLTLDDEAAPPAPDSTWVQIYSGNS 487

Query: 491  YYFGGCPDKSFGSKCKSPLGGFQGCMRLISISGKVVDLISVQQGSLGNFSDLQIDSCGIS 550
            YYFGGCPD    S+C +P+  FQGCMRLI I  +  DLISVQQGSLGNFSDL ID C I 
Sbjct: 488  YYFGGCPDNLTDSQCLNPIKAFQGCMRLIFIDNQPKDLISVQQGSLGNFSDLHIDLCSIK 547

Query: 551  DRCLPNYCEHGGECSQSWSTFHCNCTNTGYRGATCHNSIYEQSCEAYKHRGNTSGFYYID 610
            DRCLPNYCEHGG CSQSW+TF+CNC++T Y GATCHNSIYEQSCE Y+H+GNT+GF+YID
Sbjct: 548  DRCLPNYCEHGGSCSQSWTTFYCNCSDTSYTGATCHNSIYEQSCEVYRHQGNTAGFFYID 607

Query: 611  SDGSGPLEPFLLYCNMTETA-WTIIQHNGSDLTRVRNTNPENPYAGFFEYVASMEQLQAT 669
            SDGSGPL P  +YCN+TE   WT +QHN ++LTRVR  NPE PYA   +Y  SMEQL+A 
Sbjct: 608  SDGSGPLGPLQVYCNITEDKIWTSVQHNNTELTRVRGANPEKPYAMALDYGGSMEQLEAV 667

Query: 670  INRAEHCEQEFTYYCKKSRLVNKQDGTPLSWWVGRTNETQTYWGGSSPDLQKCTCGLEGN 729
            I+ +EHCEQE  Y+C++SRL+N  DGTP +WW+GR+NE   YWGGS P +Q+C CGL+ +
Sbjct: 668  IDGSEHCEQEVAYHCRRSRLLNTPDGTPFTWWIGRSNERHPYWGGSPPGVQQCECGLDES 727

Query: 730  CIDSQYYCNCDADRNEWTNDTGLLAYKEHLPVTKIVITDTGRLHSEAAYKLGPLLCQGDR 789
            C+D Q++CNCDAD++EWTNDTG L++K+HLPVT+IVITDT R +SEAA+++GPL C GDR
Sbjct: 728  CLDIQHFCNCDADKDEWTNDTGFLSFKDHLPVTQIVITDTDRSNSEAAWRIGPLRCYGDR 787

Query: 790  SFWNSASFDTEASYLHFPTFHGELSADVSFFFKTTASSGVFLENLGIADFIRIELRSPTV 849
             FWN+ SF TEASYLHFPTFH E SAD+SFFFKTTA SGVFLENLGI DFIR+E+ SP+ 
Sbjct: 788  RFWNAVSFYTEASYLHFPTFHAEFSADISFFFKTTALSGVFLENLGIKDFIRLEISSPSE 847

Query: 850  VTFSFDVGNGPFEISVQSPTHFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVL 909
            +TF+ DVGNGP E+ VQSP+  NDNQWH+VR ERN+KE SLQVD L   T+    +GH  
Sbjct: 848  ITFAIDVGNGPVELVVQSPSLLNDNQWHYVRAERNLKETSLQVDNLPRSTRETSEEGHFR 907

Query: 910  LQLNSQLFVGGTATRQRGFLGCIRSLQLNGMTLDLEERAQVTPEVQPGCRGHCSSYGKLC 969
            LQLNSQLFVGGT++RQ+GFLGCIRSL LNG  +DLEERA+VT  V+PGC GHCSSYG +C
Sbjct: 908  LQLNSQLFVGGTSSRQKGFLGCIRSLHLNGQKMDLEERAKVTSGVRPGCPGHCSSYGSIC 967

Query: 970  RNGGKCRERPIGFFCDCTFSAYTGPFCSNEISAYFGSGSSVIYNFQENYLLSKNSSSHAA 1029
             NGGKC E+  G+ CDCT S Y GPFC  E+SA F +G+SV Y FQE Y ++KN S  ++
Sbjct: 968  HNGGKCVEKHNGYLCDCTNSPYEGPFCKKEVSAVFEAGTSVTYMFQEPYPVTKNISLSSS 1027

Query: 1030 SFHGDMKLSREMIKFSFRTTRTPSLLLFVSSFYKEYLSVIIAKNGSLQIRYKLNKYQEPD 1089
            + + D   S+E I  SF TT+ PSLLLF++S  ++++ V++ KNGSLQ+RY LNK +E  
Sbjct: 1028 AIYTDSAPSKENIALSFVTTQAPSLLLFINSSSQDFVVVLLCKNGSLQVRYHLNK-EETH 1086

Query: 1090 VVNFDFKNMADGQLHHIMINREEGVVFIEIDDNRRRQVHLSSGTEFSAVKSLVLGRILEH 1149
            V   D  N A+ ++HH+ INRE   + I++D   R   + S   EF  ++SL LG++ E+
Sbjct: 1087 VFTIDADNFANRRMHHLKINREGRELTIQMDQQLRLSYNFSPEVEFRVIRSLTLGKVTEN 1146

Query: 1150 SDVDQDTALAGAQGFTGCLSAVQLSHVAPLKAALHPSHPDPVTVTGHVTESSCMAQPGTD 1209
              +D + A A A GF GC+S+VQ +H+APLKAAL  +   PVTV G +TESSC     +D
Sbjct: 1147 LGLDSEVAKANAMGFAGCMSSVQYNHIAPLKAALRHATVAPVTVHGTLTESSCGFMVDSD 1206

Query: 1210 ATSRERTHSFADHSGTIDDREPLANAIKSDSAVIGGLIAVVIFILLCITAIAVR-IYQQK 1268
              +    HS +D  G  D+REPL NA++SDSAVIGG+IAVVIFI+ CI  I  R +YQ K
Sbjct: 1207 VNAVTTVHSSSDPFGKTDEREPLTNAVRSDSAVIGGVIAVVIFIIFCIIGIMTRFLYQHK 1266

Query: 1269 RLYKRSEAKRSENVDSAEAVLKSELNIQNAVNENQKEYF 1307
            + ++ S+ K  E  ++ ++  ++E+++QN V+E ++EYF
Sbjct: 1267 QSHRTSQMKEKEYPENLDSSFRNEIDLQNTVSECKREYF 1305


>gi|239743756 PREDICTED: hypothetical protein LOC389722 isoform 2
           [Homo sapiens]
          Length = 1207

 Score = 1378 bits (3567), Expect = 0.0
 Identities = 659/919 (71%), Positives = 760/919 (82%), Gaps = 3/919 (0%)

Query: 1   MGSVTGAVLKTLLLLSTQNWNRVEAGNSYDCDDPLVSALPQASFSSSSELSSSHGPGFAR 60
           M SV  AVLK LLLL TQ W+ V AGN  DCD PL SALP++SFSSSSELSSSHGPGF+R
Sbjct: 1   MASVAWAVLKVLLLLPTQTWSPVGAGNPPDCDSPLASALPRSSFSSSSELSSSHGPGFSR 60

Query: 61  LNRRDGAGGWSPLVSNKYQWLQIDLGERMEVTAVATQGGYGSSNWVTSYLLMFSDSGWNW 120
           LNRRDGAGGW+PLVSNKYQWLQIDLGERMEVTAVATQGGYGSS+WVTSYLLMFSD G NW
Sbjct: 61  LNRRDGAGGWTPLVSNKYQWLQIDLGERMEVTAVATQGGYGSSDWVTSYLLMFSDGGRNW 120

Query: 121 KQYRQEDSIWGFSGNANADSVVYYRLQPSIKARFLRFIPLEWNPKGRIGMRIEVFGCAYR 180
           KQYR+E+SIWGF GN NADSVV+YRLQP  +ARFLRF+PL WNP+GRIGMRIEV+GCAY+
Sbjct: 121 KQYRREESIWGFPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGCAYK 180

Query: 181 SEVVDLDGKSSLLYRFDQKSLSPIKDIISLKFKTMQSDGILLHREGPNGDHITLQLRRAR 240
           SEVV  DG+S+LLY  D+K L PI+D+ISLKFK MQS+GILLHREG +G+HITL+L + +
Sbjct: 181 SEVVYFDGQSALLYTLDKKPLKPIRDVISLKFKAMQSNGILLHREGQHGNHITLELIKGK 240

Query: 241 LFLLINSGEAKLPSTSTLVNLTLGSLLDDQHWHSVLIQRLGKQVNFTVDEHRHHFHARGE 300
           L   +NSG AKLPST   V LTLGSLLDDQHWHSVLI+ L  QVNFTVD+H HHF A+G+
Sbjct: 241 LVFFLNSGNAKLPSTIAPVTLTLGSLLDDQHWHSVLIELLDTQVNFTVDKHTHHFQAKGD 300

Query: 301 FNLMNLDYEISFGGIPAPGKSVSFPHRNFHGCLENLYYNGVDIIDLAKQQKPQIIAMGNV 360
            + ++L++EISFGGI +PG+S +F  ++FHGCLENLYYNGVD+ +LAK+ KPQI+ MGNV
Sbjct: 301 SSNLDLNFEISFGGILSPGRSRAFTRKSFHGCLENLYYNGVDVTELAKKHKPQILMMGNV 360

Query: 361 SFSCSQPQSMPVTFLSSRSYLALPDFSGEEEVSATFQFRTWNKAGLLLFSELQLISGGIL 420
           SFSC QPQ++PVTFLSSRSYLALP  SGE++VS TFQFRTWN+AG LLF ELQ  SG  +
Sbjct: 361 SFSCPQPQTVPVTFLSSRSYLALPGNSGEDKVSVTFQFRTWNRAGHLLFGELQRGSGSFV 420

Query: 421 LFLSDGKLKSNLYQPGKLPSDITAGVELNDGQWHSVSLSAKKNHLSVAVDGQMASAAPLL 480
           LFL DGKLK +L+Q G+ P ++TAG  LNDGQWHSVS SAK +H++V VD   A   PL+
Sbjct: 421 LFLKDGKLKLSLFQAGQSPRNVTAGAGLNDGQWHSVSFSAKWSHMNVVVDDDTA-VQPLV 479

Query: 481 GPEQIYSGGTYYFGGCPDKSFGSKCKSPLGGFQGCMRLISISGKVVDLISVQQGSLGNFS 540
               I SG TYYFGGC   S GS CKSPLGGFQGC+RLI+I  K VD I VQQG+LG+F 
Sbjct: 480 A-VLIDSGDTYYFGGCLGNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFR 538

Query: 541 DLQIDSCGISDRCLPNYCEHGGECSQSWSTFHCNCTNTGYRGATCHNSIYEQSCEAYKHR 600
           DLQIDSCGI+DRCLP+YCEHGGECSQSW TF C+C  TGY G TCH+S+YEQSCEA+KHR
Sbjct: 539 DLQIDSCGITDRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHR 598

Query: 601 GNTSGFYYIDSDGSGPLEPFLLYCNMTETAWTIIQHNGSDLTRVRNTNPENPYAGF-FEY 659
           GN SG YYID+DGSGPL PFL+YCNMT++AWT+++H G D   +R     +P +   F Y
Sbjct: 599 GNPSGLYYIDADGSGPLGPFLVYCNMTDSAWTVVRHGGPDAVTLRGAPSGHPLSAVSFAY 658

Query: 660 VASMEQLQATINRAEHCEQEFTYYCKKSRLVNKQDGTPLSWWVGRTNETQTYWGGSSPDL 719
            A   QL+A +N AE CEQ     C  +R  + +DGTPLSWWVGRTNET T WGGS PD 
Sbjct: 659 AAGAGQLRAAVNLAERCEQRLALRCGTARRPDSRDGTPLSWWVGRTNETHTSWGGSLPDA 718

Query: 720 QKCTCGLEGNCIDSQYYCNCDADRNEWTNDTGLLAYKEHLPVTKIVITDTGRLHSEAAYK 779
           QKCTCGLEGNCIDSQYYCNCDA +NEWT+DT +L+ KEHLPVT+IV+TDTG+ HSEA Y 
Sbjct: 719 QKCTCGLEGNCIDSQYYCNCDAGQNEWTSDTIVLSQKEHLPVTQIVMTDTGQPHSEADYT 778

Query: 780 LGPLLCQGDRSFWNSASFDTEASYLHFPTFHGELSADVSFFFKTTASSGVFLENLGIADF 839
           LGPLLC+GD+SFWNSASF+TE SYLHFP FHGEL+ADV FFFKTT SSGVF+ENLGI DF
Sbjct: 779 LGPLLCRGDKSFWNSASFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGITDF 838

Query: 840 IRIELRSPTVVTFSFDVGNGPFEISVQSPTHFNDNQWHHVRVERNMKEASLQVDQLTPKT 899
           IRIELR+PT VTFSFDVGNGP E++VQSPT FNDNQWHHVR ERN+K ASLQVDQL  K 
Sbjct: 839 IRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKM 898

Query: 900 QPAPADGHVLLQLNSQLFV 918
           QPAPADGHV LQLNSQLF+
Sbjct: 899 QPAPADGHVRLQLNSQLFI 917



 Score =  336 bits (861), Expect = 1e-91
 Identities = 175/286 (61%), Positives = 219/286 (76%), Gaps = 4/286 (1%)

Query: 999  EISAYFGSGSSVIYNFQENYLLSKNSSSHAASFHGDMKLSREMIKFSFRTTRTPSLLLFV 1058
            EISAYF +GSS+ Y+FQE+Y LS+NSSS  +S + D+ L+REMI  SFRTTR+PSLLL+V
Sbjct: 918  EISAYFATGSSMTYHFQEHYTLSENSSSLVSSLYRDVTLTREMITLSFRTTRSPSLLLYV 977

Query: 1059 SSFYKEYLSVIIAKNGSLQIRYKLNKYQEPDVVNFDFKNMADGQLHHIMINREEGVVFIE 1118
            SSFY+EYLSVI+A NGSLQIRYKL+++Q PD   FDFKNMADGQLH + INREE VV +E
Sbjct: 978  SSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVE 1037

Query: 1119 IDDNRRRQVHLSSGTEFSAVKSLVLGRILEHSDVDQDTALAGAQGFTGCLSAVQLSHVAP 1178
            ++ + ++QV LSSGTEF+AVKSL+LG++LE +  D DT  A   GFTGCLSAV+    AP
Sbjct: 1038 VNQSAKKQVILSSGTEFNAVKSLILGKVLEAAGADPDTRRAATSGFTGCLSAVRFGRAAP 1097

Query: 1179 LKAALHPSHPDPVTVTGHVTE-SSCMAQPGTDATSRE---RTHSFADHSGTIDDREPLAN 1234
            LKAAL PS P  VTV GHV   + C A   + + +RE   R    A  SG +D+ EPL N
Sbjct: 1098 LKAALRPSGPSRVTVRGHVAPMARCAAGAASGSPARELAPRLAGGAGRSGPVDEGEPLVN 1157

Query: 1235 AIKSDSAVIGGLIAVVIFILLCITAIAVRIYQQKRLYKRSEAKRSE 1280
            A + DSAV+GG+IAVVIFILLCITAIA+RIYQQ++L K +E+K S+
Sbjct: 1158 ADRRDSAVMGGVIAVVIFILLCITAIAIRIYQQRKLRKENESKVSK 1203



 Score = 58.2 bits (139), Expect = 5e-08
 Identities = 64/268 (23%), Positives = 98/268 (36%), Gaps = 38/268 (14%)

Query: 757  EHLPVTKIVITDTGRLHSEAAYKLGPLLCQGDRSFWNSASFDTEASYLHFPTFHGELSAD 816
            E+L    + +T+  + H      +G +     +      +F +  SYL  P   GE    
Sbjct: 334  ENLYYNGVDVTELAKKHKPQILMMGNVSFSCPQPQTVPVTFLSSRSYLALPGNSGEDKVS 393

Query: 817  VSFFFKTTASSGVFLEN---LGIADFIRIELRSPTVVTFSFDVGNGPFEISVQSPTHFND 873
            V+F F+T   +G  L      G   F+ + L+   +    F  G  P  ++  +    ND
Sbjct: 394  VTFQFRTWNRAGHLLFGELQRGSGSFV-LFLKDGKLKLSLFQAGQSPRNVTAGAG--LND 450

Query: 874  NQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFVGGTATRQRG------ 927
             QWH V         ++ VD  T   QP  A   VL+      + GG      G      
Sbjct: 451  GQWHSVSFSAKWSHMNVVVDDDTA-VQPLVA---VLIDSGDTYYFGGCLGNSSGSGCKSP 506

Query: 928  ---FLGCIRSLQLNGMTLDLEERAQVTPEVQPGCRG-----HCSSYG-------KLCRNG 972
               F GC+R + +    +D          VQ G  G        S G         C +G
Sbjct: 507  LGGFQGCLRLITIGDKAVD-------PILVQQGALGSFRDLQIDSCGITDRCLPSYCEHG 559

Query: 973  GKCRERPIGFFCDCTFSAYTGPFCSNEI 1000
            G+C +    F CDC  + YTG  C + +
Sbjct: 560  GECSQSWDTFSCDCLGTGYTGETCHSSL 587


>gi|7662350 cell recognition molecule Caspr2 precursor [Homo sapiens]
          Length = 1331

 Score = 1286 bits (3328), Expect = 0.0
 Identities = 634/1302 (48%), Positives = 873/1302 (67%), Gaps = 27/1302 (2%)

Query: 28   SYDCDDPLVSALPQASFSSSSELSSSHGPGFARLNRRDGAGGWSPLVSNKYQWLQIDLGE 87
            S  CD+PLVS LP  +FSSSS +S S+ PG+A++N+R GAGGWSP  S+ YQWLQ+D G 
Sbjct: 32   SQKCDEPLVSGLPHVAFSSSSSISGSYSPGYAKINKRGGAGGWSPSDSDHYQWLQVDFGN 91

Query: 88   RMEVTAVATQGGYGSSNWVTSYLLMFSDSGWNWKQYRQEDSIWGFSGNANADSVVYYRLQ 147
            R +++A+ATQG Y SS+WVT Y +++SD+G NWK Y Q+ +IW F GN N+D VV + LQ
Sbjct: 92   RKQISAIATQGRYSSSDWVTQYRMLYSDTGRNWKPYHQDGNIWAFPGNINSDGVVRHELQ 151

Query: 148  PSIKARFLRFIPLEWNPKGRIGMRIEVFGCAYRSEVVDLDGKSSLLYRFDQKSLSPIKDI 207
              I AR++R +PL+WN +GRIG+RIEV+GC+Y ++V++ DG   L YRF  K +  +KD+
Sbjct: 152  HPIIARYVRIVPLDWNGEGRIGLRIEVYGCSYWADVINFDGHVVLPYRFRNKKMKTLKDV 211

Query: 208  ISLKFKTMQSDGILLHREGPNGDHITLQLRRARLFLLINSGEAKLPSTSTLVNLTLGSLL 267
            I+L FKT +S+G++LH EG  GD+ITL+L++A+L L +N G  +L       ++  GSLL
Sbjct: 212  IALNFKTSESEGVILHGEGQQGDYITLELKKAKLVLSLNLGSNQLGPIYGHTSVMTGSLL 271

Query: 268  DDQHWHSVLIQRLGKQVNFTVDEHRHHFHARGEFNLMNLDYEISFGGIPAPGKSVSFPHR 327
            DD HWHSV+I+R G+ +N T+D    HF   GEF+ ++LDYEI+FGGIP  GK  S   +
Sbjct: 272  DDHHWHSVVIERQGRSINLTLDRSMQHFRTNGEFDYLDLDYEITFGGIPFSGKPSSSSRK 331

Query: 328  NFHGCLENLYYNGVDIIDLAKQQKPQIIAMGNVSFSCSQPQSMPVTFLSSRSYLALPDFS 387
            NF GC+E++ YNGV+I DLA+++K +   +GN+SFSC +P ++PV F ++ SYL +P   
Sbjct: 332  NFKGCMESINYNGVNITDLARRKKLEPSNVGNLSFSCVEPYTVPV-FFNATSYLEVPGRL 390

Query: 388  GEEEVSATFQFRTWNKAGLLLFSELQLISGGILLFLSDGK--LKSNLYQPGKLPSDITAG 445
             ++  S +FQFRTWN  GLL+FS      G + + L++ K  +  N+ Q      DI++G
Sbjct: 391  NQDLFSVSFQFRTWNPNGLLVFSHFADNLGNVEIDLTESKVGVHINITQTKMSQIDISSG 450

Query: 446  VELNDGQWHSVSLSAKKNHLSVAVDGQMASAAPLLGPEQIYSGGTYYFGGCPDKSFGSKC 505
              LNDGQWH V   AK+N   + +DG  ASA     P Q+ +G  Y+FGG  ++   S  
Sbjct: 451  SGLNDGQWHEVRFLAKENFAILTIDGDEASAVRTNSPLQVKTGEKYFFGGFLNQMNNSSH 510

Query: 506  KSPLGGFQGCMRLISISGKVVDLISVQQGSLGNFSDLQIDSCGISDRCLPNYCEHGGECS 565
                  FQGCM+LI +  ++V+L  V Q   G+F+++ ID C I DRC+PN+CEHGG+CS
Sbjct: 511  SVLQPSFQGCMQLIQVDDQLVNLYEVAQRKPGSFANVSIDMCAIIDRCVPNHCEHGGKCS 570

Query: 566  QSWSTFHCNCTNTGYRGATCHNSIYEQSCEAYKHRGNTSGFYYIDSDGSGPLEPFLLYCN 625
            Q+W +F C C  TGY GATCHNSIYE SCEAYKH G TS +Y+ID DGSGPL P  +YCN
Sbjct: 571  QTWDSFKCTCDETGYSGATCHNSIYEPSCEAYKHLGQTSNYYWIDPDGSGPLGPLKVYCN 630

Query: 626  MTE-TAWTIIQHNGSDLTRVRNTNPENPYAGFFEYVASMEQLQATINRAEHCEQEFTYYC 684
            MTE   WTI+ H+    T V   NPE        Y ASM+Q+ A  + AE+CEQ  +Y+C
Sbjct: 631  MTEDKVWTIVSHDLQMQTPVVGYNPEKYSVTQLVYSASMDQISAITDSAEYCEQYVSYFC 690

Query: 685  KKSRLVNKQDGTPLSWWVGRTNETQTYWGGSSPDLQKCTCGLEGNCIDSQYYCNCDADRN 744
            K SRL+N  DG+P +WWVG+ NE   YWGGS P +QKC CG+E NC D +YYCNCDAD  
Sbjct: 691  KMSRLLNTPDGSPYTWWVGKANEKHYYWGGSGPGIQKCACGIERNCTDPKYYCNCDADYK 750

Query: 745  EWTNDTGLLAYKEHLPVTKIVITDTGRLHSEAAYKLGPLLCQGDRSFWNSASFDTEASYL 804
            +W  D G L+YK+HLPV+++V+ DT R  SEA   +GPL CQGDR++WN+ASF   +SYL
Sbjct: 751  QWRKDAGFLSYKDHLPVSQVVVGDTDRQGSEAKLSVGPLRCQGDRNYWNAASFPNPSSYL 810

Query: 805  HFPTFHGELSADVSFFFKTTASSGVFLENLGIADFIRIELRSPTVVTFSFDVGNGPFEIS 864
            HF TF GE SAD+SF+FKT    GVFLEN+G  DFI++EL+S T V+FSFDVGNGP EI 
Sbjct: 811  HFSTFQGETSADISFYFKTLTPWGVFLENMGKEDFIKLELKSATEVSFSFDVGNGPVEIV 870

Query: 865  VQSPTHFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFVGGTATR 924
            V+SPT  ND+QWH V  ERN+K+ASLQVD+L  + + AP +GH  L+L SQLFVGG A  
Sbjct: 871  VRSPTPLNDDQWHRVTAERNVKQASLQVDRLPQQIRKAPTEGHTRLELYSQLFVGG-AGG 929

Query: 925  QRGFLGCIRSLQLNGMTLDLEERAQVTPEVQPGCRGHCSSYGKLCRNGGKCRERPIGFFC 984
            Q+GFLGCIRSL++NG+TLDLEERA+VT     GC GHC+SYG  C NGGKC ER  G+ C
Sbjct: 930  QQGFLGCIRSLRMNGVTLDLEERAKVTSGFISGCSGHCTSYGTNCENGGKCLERYHGYSC 989

Query: 985  DCTFSAYTGPFCSNEISAYFGSGSSVIYNFQENYLLSKNSSSHA------ASFHGDMKLS 1038
            DC+ +AY G FC+ ++ A+F  G  + YNFQ     +++SSS         + H D  L+
Sbjct: 990  DCSNTAYDGTFCNKDVGAFFEEGMWLRYNFQAPATNARDSSSRVDNAPDQQNSHPD--LA 1047

Query: 1039 REMIKFSFRTTRTPSLLLFVSSFYKEYLSVIIAKNGSLQIRYKLNKYQEPDVVNFDFKNM 1098
            +E I+FSF TT+ P +LL++SSF  ++L+V++   GSLQIRY L   +EP  ++ D +NM
Sbjct: 1048 QEEIRFSFSTTKAPCILLYISSFTTDFLAVLVKPTGSLQIRYNLGGTREPYNIDVDHRNM 1107

Query: 1099 ADGQLHHIMINREEGVVFIEIDDNRRRQVHL--SSGTEFSAVKSLVLGRILEHSDVDQDT 1156
            A+GQ H + I R E  +F+++D       HL  SS T F++ KSL LG+++E   +DQ+ 
Sbjct: 1108 ANGQPHSVNITRHEKTIFLKLDHYPSVSYHLPSSSDTLFNSPKSLFLGKVIETGKIDQEI 1167

Query: 1157 ALAGAQGFTGCLSAVQLSHVAPLKAALHPSHPDP-VTVTGHVTESSCMAQPGTDATSRER 1215
                  GFTGCLS VQ + +APLKAAL  ++    V + G + ES+C A P T +     
Sbjct: 1168 HKYNTPGFTGCLSRVQFNQIAPLKAALRQTNASAHVHIQGELVESNCGASPLTLSPMSSA 1227

Query: 1216 THSF---------ADHSGTIDDREPLANAIKSDSAVIGGLIAVVIFILLCITAIAVR-IY 1265
            T  +         AD        + + N +  +SA+IGG+IAVVIF +LC     +R ++
Sbjct: 1228 TDPWHLDHLDSASADFPYNPGQGQAIRNGVNRNSAIIGGVIAVVIFTILCTLVFLIRYMF 1287

Query: 1266 QQKRLYKRSEAKRSENVDSAE-AVLKSELNIQNAVNENQKEY 1306
            + K  Y  +EAK +E+ +SA+ A++ ++ N    ++E++KE+
Sbjct: 1288 RHKGTYHTNEAKGAESAESADAAIMNNDPNFTETIDESKKEW 1329


>gi|4505463 contactin associated protein 1 precursor [Homo sapiens]
          Length = 1384

 Score =  931 bits (2406), Expect = 0.0
 Identities = 478/1244 (38%), Positives = 722/1244 (58%), Gaps = 68/1244 (5%)

Query: 24   EAGNSYDCDDPLVSALPQASFSSSSELSSSHGPGFARLNRRDGAGGWSPLVSNKYQWLQI 83
            E    Y CD+ LV  L   S  +SS  S    P FARL+   G  GWSP + +   WLQI
Sbjct: 18   EGWGYYGCDEELVGPLYARSLGASSYYSLLTAPRFARLH---GISGWSPRIGDPNPWLQI 74

Query: 84   DLGERMEVTAVATQGGYGSSNWVTSYLLMFSDSGWNWKQYRQEDSIWGFSGNANADSVVY 143
            DL ++  + AVATQG + S +WVT Y+L++ D   +W  + Q      F GN N  +VV 
Sbjct: 75   DLMKKHRIRAVATQGSFNSWDWVTRYMLLYGDRVDSWTPFYQRGHNSTFFGNVNESAVVR 134

Query: 144  YRLQPSIKARFLRFIPLEWNPKGRIGMRIEVFGCAYRSEVVDLDGKSSLLYRFDQKSLSP 203
            + L     AR++R +PL WNP+G+IG+R+ ++GC Y+++++  DG  ++ YRF +     
Sbjct: 135  HDLHFHFTARYIRIVPLAWNPRGKIGLRLGLYGCPYKADILYFDGDDAISYRFPRGVSRS 194

Query: 204  IKDIISLKFKTMQSDGILLHREGPNGDHITLQLRRARLFLLINSGEAKLPSTSTLVNLTL 263
            + D+ +  FKT + DG+LLH EG  GD++TL+L  A L L ++ G + +        ++ 
Sbjct: 195  LWDVFAFSFKTEEKDGLLLHAEGAQGDYVTLELEGAHLLLHMSLGSSPIQPRPGHTTVSA 254

Query: 264  GSLLDDQHWHSVLIQRLGKQVNFTVDEHRHHFHARGEFNLMNLDYEISFGG-IPAPGKSV 322
            G +L+DQHWH V + R G+ VNFT+D +   F   G+F  +NLD E+  GG + A  K++
Sbjct: 255  GGVLNDQHWHYVRVDRFGRDVNFTLDGYVQRFILNGDFERLNLDTEMFIGGLVGAARKNL 314

Query: 323  SFPHRNFHGCLENLYYNGVDIIDLAKQQKPQIIAMGNVSFSCSQPQSMPVTFLSSRSYLA 382
            ++ H NF GC+EN+ +N V+I DLA ++  +I   G V+F C  P   P+ F    +++ 
Sbjct: 315  AYRH-NFRGCIENVIFNRVNIADLAVRRHSRITFEGKVAFRCLDPVPHPINFGGPHNFVQ 373

Query: 383  LPDFSGEEEVSATFQFRTWNKAGLLLFSELQLISGGILLFLSDGKLKSNLYQPGKLPSDI 442
            +P F     ++ +F+FRTW+  GLLLFS L    G + L LS+G++  ++ Q G+     
Sbjct: 374  VPGFPRRGRLAVSFRFRTWDLTGLLLFSRLGDGLGHVELTLSEGQVNVSIAQSGRKKLQF 433

Query: 443  TAGVELNDGQWHSVSLSAKKNHLSVAVDGQMASAAPLLGPEQIYSGGTYYFGGCPDKSFG 502
             AG  LNDG WH V+  A++NH  +++D    +   +  P  I +G +Y+FGGCP  +  
Sbjct: 434  AAGYRLNDGFWHEVNFVAQENHAVISIDDVEGAEVRVSYPLLIRTGTSYFFGGCPKPASR 493

Query: 503  SKCKSPLGGFQGCMRLISISGKVVDLISVQQGSLGNFSDLQIDSCGISDRCLPNYCEHGG 562
              C S    F GCM L+ + G++V+L  V+   LG ++++  D+CGI+DRC PN CEH G
Sbjct: 494  WDCHSNQTAFHGCMELLKVDGQLVNLTLVEGRRLGFYAEVLFDTCGITDRCSPNMCEHDG 553

Query: 563  ECSQSWSTFHCNCTNTGYRGATCHNSIYEQSCEAYKHRGNTSGFYYIDSDGSGPLEPFLL 622
             C QSW  F C C  TGY+G TCH  +Y++SCEAY+  G TSG + ID DGSGPL+PF++
Sbjct: 554  RCYQSWDDFICYCELTGYKGETCHTPLYKESCEAYRLSGKTSGNFTIDPDGSGPLKPFVV 613

Query: 623  YCNMTET-AWTIIQHNGSDLTRVRNTNPENPYAGFFEYV-ASMEQLQATINRAEHCEQEF 680
            YC++ E  AWT+++H+    TRV  ++ E P+ G  +Y  AS E++ A  N ++HCEQ  
Sbjct: 614  YCDIRENRAWTVVRHDRLWTTRVTGSSMERPFLGAIQYWNASWEEVSALANASQHCEQWI 673

Query: 681  TYYCKKSRLVNKQDGTPLSWWVGRTNETQTYWGGSSPDLQKCTCGLEGNCIDSQYYCNCD 740
             + C  SRL+N   G P S+W+GR  E   YWGGS P +Q+C CGL+ +C+D   YCNCD
Sbjct: 674  EFSCYNSRLLNTAGGYPYSFWIGRNEEQHFYWGGSQPGIQRCACGLDRSCVDPALYCNCD 733

Query: 741  ADRNEWTNDTGLLAYKEHLPVTKIVITDTGRLHSEAAYKLGPLLCQGDRSFWNSASFDTE 800
            AD+ +W  D GLL + +HLPVT++VI DT R  SEA + L PL C GDR+ WN+ SF T 
Sbjct: 734  ADQPQWRTDKGLLTFVDHLPVTQVVIGDTNRSTSEAQFFLRPLRCYGDRNSWNTISFHTG 793

Query: 801  ASYLHFPTFHGELSADVSFFFKTTASSGVFLENLG------IADFIRIELRSPTVVTFSF 854
            A+ L FP      S DVSF+F+T+A SGVFLEN+G         ++R+EL +   V F+F
Sbjct: 794  AA-LRFPPIRANHSLDVSFYFRTSAPSGVFLENMGGPYCQWRRPYVRVELNTSRDVVFAF 852

Query: 855  DVGNGPFEISVQSPT-HFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLN 913
            DVGNG   ++V S    FND++WH VR E N+K+A L+VD      +P P   ++ ++ +
Sbjct: 853  DVGNGDENLTVHSDDFEFNDDEWHLVRAEINVKQARLRVDHRPWVLRPMPLQTYIWMEYD 912

Query: 914  SQLFVGGTATRQRGFLGCIRSLQLNGMTLDLEERAQVTPEVQPGCRGHCSSYGKLCRNGG 973
              L+VG    ++R F+GC+R+++LNG+TL+LE RA  +    P C GHC+     C +GG
Sbjct: 913  QPLYVGSAELKRRPFVGCLRAMRLNGVTLNLEGRANASEGTSPNCTGHCAHPRLPCFHGG 972

Query: 974  KCRERPIGFFCDCTFSAYTGPFCSNEISAYFGSGSSVIYNFQE----------------- 1016
            +C ER   + CDC  +A+ GP+C+++I  +F  G+ + YN Q                  
Sbjct: 973  RCVERYSYYTCDCDLTAFDGPYCNHDIGGFFEPGTWMRYNLQSALRSAAREFSHMLSRPV 1032

Query: 1017 -----NYLLSKNSSSHAASFHGD---------------------MKLSREMIKFSFRTTR 1050
                  Y+   ++  +   +HG                        ++ E + FSF T+ 
Sbjct: 1033 PGYEPGYIPGYDTPGYVPGYHGPGYRLPDYPRPGRPVPGYRGPVYNVTGEEVSFSFSTSS 1092

Query: 1051 TPSLLLFVSSFYKEYLSVIIAKNGSLQIRYKLNKYQEPDVVNFDFKNMADGQLHHIMINR 1110
             P++LL+VSSF ++Y++V+I  +G+LQ+RY+L     P V     + + DGQ H I I R
Sbjct: 1093 APAVLLYVSSFVRDYMAVLIKDDGTLQLRYQLG--TSPYVYQLTTRPVTDGQPHSINITR 1150

Query: 1111 EEGVVFIEID--DNRRRQVHLSSGTEFSAVKSLVLGRILEHSDVDQDTALAGAQGFTGCL 1168
                +FI++D      ++  L   ++  + K+L LGR++E   +D +       GF+GCL
Sbjct: 1151 VYRNLFIQVDYFPLTEQKFSLLVDSQLDSPKALYLGRVMETGVIDPEIQRYNTPGFSGCL 1210

Query: 1169 SAVQLSHVAPLKAALHPSHP------DPVTVTGHVTESSCMAQP 1206
            S V+ ++VAPLK       P      + + V G ++ES+C A P
Sbjct: 1211 SGVRFNNVAPLKTHFRTPRPMTAELAEALRVQGELSESNCGAMP 1254


>gi|239743797 PREDICTED: similar to cell recognition molecule CASPR3
            [Homo sapiens]
          Length = 944

 Score =  740 bits (1911), Expect = 0.0
 Identities = 353/468 (75%), Positives = 400/468 (85%), Gaps = 1/468 (0%)

Query: 695  GTPLSWWVGRTNETQTYWGGSSPDLQKCTCGLEGNCIDSQYYCNCDADRNEWTNDTGLLA 754
            GTPLSWWVGRTNET T WGGS PD QKCTCGLEGNCIDSQYYCNCDA RNEWT+DT +L+
Sbjct: 428  GTPLSWWVGRTNETHTSWGGSLPDAQKCTCGLEGNCIDSQYYCNCDAGRNEWTSDTIVLS 487

Query: 755  YKEHLPVTKIVITDTGRLHSEAAYKLGPLLCQGDRSFWNSASFDTEASYLHFPTFHGELS 814
             KEHLPVT+IV+TD G+ HSEA Y LGPLLC+GD+SFWNSASF+TE SYLHFP FHGEL+
Sbjct: 488  QKEHLPVTQIVMTDAGQPHSEADYTLGPLLCRGDKSFWNSASFNTETSYLHFPAFHGELT 547

Query: 815  ADVSFFFKTTASSGVFLENLGIADFIRIELRSPTVVTFSFDVGNGPFEISVQSPTHFNDN 874
            ADV FFFKTT SSGVF+ENLGI DFIRIELR+PT VTFSFDVGNGP E++VQSPT FNDN
Sbjct: 548  ADVCFFFKTTVSSGVFMENLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDN 607

Query: 875  QWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFVGGTATRQRGFLGCIRS 934
            QWHHVR ERN+K ASLQVDQL  K QPAPADGHV LQLNSQLF+GGTATRQRGFLGCIRS
Sbjct: 608  QWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQRGFLGCIRS 667

Query: 935  LQLNGMTLDLEERAQVTPEVQPGCRGHCSSYGKLCRNGGKCRERPIGFFCDCTFSAYTGP 994
            LQLNG+ LDLEERA V P V+PGC GHCS+YG LCRNGG+CRE+  G  CDC FSAY GP
Sbjct: 668  LQLNGVALDLEERATVMPGVEPGCAGHCSTYGHLCRNGGRCREKRRGVTCDCAFSAYDGP 727

Query: 995  FCSNEISAYFGSGSSVIYNFQENYLLSKNSSSHAASFHGDMKLSREMIKFSFRTTRTPSL 1054
            FCSNEISAYF +GSS+ Y+FQE+Y LS+NSSS  +S H D+ L+REMI  SFRTTRTPSL
Sbjct: 728  FCSNEISAYFATGSSMTYHFQEHYTLSENSSSLVSSLHRDVTLTREMITLSFRTTRTPSL 787

Query: 1055 LLFVSSFYKEYLSVIIAKNGSLQIRYKLNKYQEPDVVNFDFKNMADGQLHHIMINREEGV 1114
            LL+VSSFY+EYLSVI+A NGSLQIRYKL+++Q PD   FDFKNMADGQLH + INREE V
Sbjct: 788  LLYVSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAV 847

Query: 1115 VFIEIDDNRRRQVHLSSGTEFSAVKSLVLGRILEHS-DVDQDTALAGA 1161
            V +E++ + ++QV LSSGTEF+AVKSL+LG++L  S  VD+   L  A
Sbjct: 848  VMVEVNQSAKKQVILSSGTEFNAVKSLILGKVLGRSGPVDEGEPLVNA 895



 Score =  227 bits (579), Expect = 5e-59
 Identities = 100/133 (75%), Positives = 113/133 (84%)

Query: 496 CPDKSFGSKCKSPLGGFQGCMRLISISGKVVDLISVQQGSLGNFSDLQIDSCGISDRCLP 555
           C   S GS CKSPLGGFQGC+RLI+I  K VD I VQQG+LG+F DLQIDSCGI+DRCLP
Sbjct: 187 CLGNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLP 246

Query: 556 NYCEHGGECSQSWSTFHCNCTNTGYRGATCHNSIYEQSCEAYKHRGNTSGFYYIDSDGSG 615
           +YCEHGGECSQSW TF C+C  TGY G TCH+S+YEQSCEA+KHRGN SG YYID+DGSG
Sbjct: 247 SYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYIDADGSG 306

Query: 616 PLEPFLLYCNMTE 628
           PL PFL+YCNMT+
Sbjct: 307 PLGPFLVYCNMTD 319



 Score = 79.0 bits (193), Expect = 3e-14
 Identities = 39/58 (67%), Positives = 49/58 (84%)

Query: 1223 SGTIDDREPLANAIKSDSAVIGGLIAVVIFILLCITAIAVRIYQQKRLYKRSEAKRSE 1280
            SG +D+ EPL NA + DSAVIGG+IAV IFILLCITAIA+RIYQQ++L K +E+K S+
Sbjct: 883  SGPVDEGEPLVNADRRDSAVIGGVIAVEIFILLCITAIAIRIYQQRKLRKENESKVSK 940



 Score = 65.1 bits (157), Expect = 4e-10
 Identities = 84/345 (24%), Positives = 127/345 (36%), Gaps = 71/345 (20%)

Query: 373 TFLSSRSYLALPDFSGEEEVSATFQFRTWNKAGLLLFSELQLISGGILLFLSDGKLKSNL 432
           +F +  SYL  P F GE      F F+T   +G+  F E   I+  I + L      +  
Sbjct: 529 SFNTETSYLHFPAFHGELTADVCFFFKTTVSSGV--FMENLGITDFIRIELRAPTEVTFS 586

Query: 433 YQPGKLPSDIT--AGVELNDGQWHSVSLSAKKNHLSVAVDG--QMASAAPLLGPEQIYSG 488
           +  G  P ++T  +    ND QWH V         S+ VD   Q    AP  G  ++   
Sbjct: 587 FDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLN 646

Query: 489 GTYYFGGCPDKSFGSKCKSPLGGFQGCMRLISISGKVVDLIS-------VQQGSLGNFSD 541
              + GG   +           GF GC+R + ++G  +DL         V+ G  G+ S 
Sbjct: 647 SQLFIGGTATRQ---------RGFLGCIRSLQLNGVALDLEERATVMPGVEPGCAGHCST 697

Query: 542 LQIDSCGISDRCLPNYCEHGGECSQSWSTFHCNCTNTGYRGATCHNSIYEQSCEAYKHRG 601
                         + C +GG C +      C+C  + Y G  C N I      AY   G
Sbjct: 698 YG------------HLCRNGGRCREKRRGVTCDCAFSAYDGPFCSNEI-----SAYFATG 740

Query: 602 NTSGF----YYIDSDGSGPL------------------------EPFLLYCN--MTETAW 631
           ++  +    +Y  S+ S  L                           LLY +    E   
Sbjct: 741 SSMTYHFQEHYTLSENSSSLVSSLHRDVTLTREMITLSFRTTRTPSLLLYVSSFYEEYLS 800

Query: 632 TIIQHNGSDLTRVRNTNPENPYAGFFEY--VASMEQLQATINRAE 674
            I+ +NGS   R +    +NP A  F++  +A  +  Q  INR E
Sbjct: 801 VILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREE 845



 Score = 35.0 bits (79), Expect = 0.47
 Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 18/76 (23%)

Query: 925  QRGFLGCIRSLQLNGMTLDLEERAQVTPEVQPGCRGHCSSYGKLCRNGGKCRERPIGFFC 984
            Q+G LG  R LQ++           +T    P       SY   C +GG+C +    F C
Sbjct: 223  QQGALGSFRDLQIDS--------CGITDRCLP-------SY---CEHGGECSQSWDTFSC 264

Query: 985  DCTFSAYTGPFCSNEI 1000
            DC  + YTG  C + +
Sbjct: 265  DCLGTGYTGETCHSSL 280



 Score = 31.2 bits (69), Expect = 6.8
 Identities = 36/133 (27%), Positives = 54/133 (40%), Gaps = 16/133 (12%)

Query: 212 FKTMQSDGILLHREGPNGDHITLQLRRARLFLLINSGEAKLPSTSTLVNLTLGSLLDDQH 271
           FKT  S G+ +   G   D I ++LR A   +  +      P   T+ + T     +D  
Sbjct: 554 FKTTVSSGVFMENLGIT-DFIRIELR-APTEVTFSFDVGNGPCEVTVQSPTP---FNDNQ 608

Query: 272 WHSVLIQRLGKQVNFTVDEHRHHFH---ARGEFNLMNLDYEISFGGIPAPGKSVSFPHRN 328
           WH V  +R  K  +  VD+         A G   L  L+ ++  GG        +   R 
Sbjct: 609 WHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQ-LNSQLFIGG-------TATRQRG 660

Query: 329 FHGCLENLYYNGV 341
           F GC+ +L  NGV
Sbjct: 661 FLGCIRSLQLNGV 673


>gi|239743729 PREDICTED: similar to contactin associated
           protein-like 3B [Homo sapiens]
          Length = 380

 Score =  551 bits (1420), Expect = e-156
 Identities = 263/357 (73%), Positives = 306/357 (85%)

Query: 1   MGSVTGAVLKTLLLLSTQNWNRVEAGNSYDCDDPLVSALPQASFSSSSELSSSHGPGFAR 60
           M SV  AVLK LLLL TQ W+ V AGN  DCD PL SALP++SFSSSSELSSSHGPGF+R
Sbjct: 1   MASVAWAVLKVLLLLPTQTWSPVGAGNPPDCDAPLASALPRSSFSSSSELSSSHGPGFSR 60

Query: 61  LNRRDGAGGWSPLVSNKYQWLQIDLGERMEVTAVATQGGYGSSNWVTSYLLMFSDSGWNW 120
           LNRRDGAGGW+PLVSNKYQWLQIDLGERMEVTAVATQGGYGSS+WVTSYLLMFSD G NW
Sbjct: 61  LNRRDGAGGWTPLVSNKYQWLQIDLGERMEVTAVATQGGYGSSDWVTSYLLMFSDGGRNW 120

Query: 121 KQYRQEDSIWGFSGNANADSVVYYRLQPSIKARFLRFIPLEWNPKGRIGMRIEVFGCAYR 180
           KQYR+E+SIWGF GN NADSVV+YRLQP  +ARFLRF+PL WNP+GRIGMRIEV+GCAY+
Sbjct: 121 KQYRREESIWGFPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGCAYK 180

Query: 181 SEVVDLDGKSSLLYRFDQKSLSPIKDIISLKFKTMQSDGILLHREGPNGDHITLQLRRAR 240
           SEVV  DG+S+LLY  D+K L PI+D+ISLKFK MQS+GILLHREG +G+HITL+L + +
Sbjct: 181 SEVVYFDGQSALLYTLDKKPLKPIRDVISLKFKAMQSNGILLHREGQHGNHITLELIKRK 240

Query: 241 LFLLINSGEAKLPSTSTLVNLTLGSLLDDQHWHSVLIQRLGKQVNFTVDEHRHHFHARGE 300
           L   +NSG AKLPST   V LTLGSLLDDQHWHSVLI+ L  QVNFTVD+H HHF A+G+
Sbjct: 241 LVFFLNSGNAKLPSTIAPVTLTLGSLLDDQHWHSVLIELLHTQVNFTVDKHTHHFQAKGD 300

Query: 301 FNLMNLDYEISFGGIPAPGKSVSFPHRNFHGCLENLYYNGVDIIDLAKQQKPQIIAM 357
            + ++L++EISFGGIP PG+S +F  ++FHGCLENLYYNGVD+ +LAK+ KPQI+ M
Sbjct: 301 SSNLDLNFEISFGGIPTPGRSRAFTRKSFHGCLENLYYNGVDVTELAKKHKPQILMM 357



 Score = 39.3 bits (90), Expect = 0.025
 Identities = 39/146 (26%), Positives = 63/146 (43%), Gaps = 18/146 (12%)

Query: 817 VSFFFKTTASSGVFLENLGI-ADFIRIELRSPTVVTFSFDVGNGPFEISVQSPTH----- 870
           +S  FK   S+G+ L   G   + I +EL    +V F  + GN     ++   T      
Sbjct: 208 ISLKFKAMQSNGILLHREGQHGNHITLELIKRKLVFF-LNSGNAKLPSTIAPVTLTLGSL 266

Query: 871 FNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFVGGTAT------- 923
            +D  WH V +E    + +  VD+ T   Q      +  L LN ++  GG  T       
Sbjct: 267 LDDQHWHSVLIELLHTQVNFTVDKHTHHFQAKGDSSN--LDLNFEISFGGIPTPGRSRAF 324

Query: 924 RQRGFLGCIRSLQLNGMTLDLEERAQ 949
            ++ F GC+ +L  NG  +D+ E A+
Sbjct: 325 TRKSFHGCLENLYYNG--VDVTELAK 348



 Score = 33.9 bits (76), Expect = 1.0
 Identities = 34/139 (24%), Positives = 52/139 (37%), Gaps = 17/139 (12%)

Query: 395 TFQFRTWNKAGLLLFSE--------LQLISGGILLFLSDG--KLKSNLYQPGKLPSDITA 444
           + +F+     G+LL  E        L+LI   ++ FL+ G  KL S +      P  +T 
Sbjct: 209 SLKFKAMQSNGILLHREGQHGNHITLELIKRKLVFFLNSGNAKLPSTI-----APVTLTL 263

Query: 445 GVELNDGQWHSVSLSAKKNHLSVAVDGQMASAAPLLGPEQIYSGGTYYFGGCPDKSFGSK 504
           G  L+D  WHSV +      ++  VD              +       FGG P    G  
Sbjct: 264 GSLLDDQHWHSVLIELLHTQVNFTVDKHTHHFQAKGDSSNLDLNFEISFGGIPTP--GRS 321

Query: 505 CKSPLGGFQGCMRLISISG 523
                  F GC+  +  +G
Sbjct: 322 RAFTRKSFHGCLENLYYNG 340


>gi|169184330 PREDICTED: novel protein similar to contactin associated
            protein-like 3 (CNTNAP3) [Homo sapiens]
          Length = 291

 Score =  336 bits (861), Expect = 1e-91
 Identities = 176/286 (61%), Positives = 218/286 (76%), Gaps = 4/286 (1%)

Query: 999  EISAYFGSGSSVIYNFQENYLLSKNSSSHAASFHGDMKLSREMIKFSFRTTRTPSLLLFV 1058
            +ISAYF +GSS+ Y+FQE+Y LS+NSSS  +S H D+ L+REMI  SFRTTRTPSLLL+V
Sbjct: 2    KISAYFATGSSMTYHFQEHYTLSENSSSLVSSLHRDVTLTREMITLSFRTTRTPSLLLYV 61

Query: 1059 SSFYKEYLSVIIAKNGSLQIRYKLNKYQEPDVVNFDFKNMADGQLHHIMINREEGVVFIE 1118
            SSFY+EYLSVI+A NGSLQIRYKL+++Q PD   FDFKNMADGQLH + INREE VV +E
Sbjct: 62   SSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVE 121

Query: 1119 IDDNRRRQVHLSSGTEFSAVKSLVLGRILEHSDVDQDTALAGAQGFTGCLSAVQLSHVAP 1178
            ++ + ++QV LSSGTEF+AVKSL+LG++LE +  D DT  A   GFTGCLSAV+    AP
Sbjct: 122  VNQSAKKQVILSSGTEFNAVKSLILGKVLEAAGADPDTRRAATSGFTGCLSAVRFGCAAP 181

Query: 1179 LKAALHPSHPDPVTVTGHVTE-SSCMAQPGTDATSRE---RTHSFADHSGTIDDREPLAN 1234
            LKAAL PS P  VTV GHV   + C A   + + +RE   R    A  SG +D+ EPL N
Sbjct: 182  LKAALRPSGPSRVTVRGHVAPMARCAAGAASGSPARELAPRLAGGAGRSGPVDEGEPLVN 241

Query: 1235 AIKSDSAVIGGLIAVVIFILLCITAIAVRIYQQKRLYKRSEAKRSE 1280
            A + DSAVIGG+IAV IFILLCITAIA+RIYQQ++L K +E+K S+
Sbjct: 242  ADRRDSAVIGGVIAVEIFILLCITAIAIRIYQQRKLRKENESKVSK 287


>gi|239758135 PREDICTED: similar to cell recognition molecule CASPR3
            [Homo sapiens]
          Length = 140

 Score =  193 bits (490), Expect = 1e-48
 Identities = 93/136 (68%), Positives = 116/136 (85%)

Query: 1012 YNFQENYLLSKNSSSHAASFHGDMKLSREMIKFSFRTTRTPSLLLFVSSFYKEYLSVIIA 1071
            Y+FQE+Y LS+NSSS  +S H D+ L+REMI  SFRTTRTPSLLL+VSSFY+EYLSVI+A
Sbjct: 3    YHFQEHYTLSENSSSLVSSLHRDVTLTREMITLSFRTTRTPSLLLYVSSFYEEYLSVILA 62

Query: 1072 KNGSLQIRYKLNKYQEPDVVNFDFKNMADGQLHHIMINREEGVVFIEIDDNRRRQVHLSS 1131
             NGSLQIRYKL+++Q PD   FDFKNMADGQLH + INREE VV +E++ + ++QV LSS
Sbjct: 63   NNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVEVNQSAKKQVILSS 122

Query: 1132 GTEFSAVKSLVLGRIL 1147
            GTEF+AVKSL+LG++L
Sbjct: 123  GTEFNAVKSLILGKVL 138


>gi|21166380 neurexin 2 isoform alpha-2 precursor [Homo sapiens]
          Length = 1642

 Score =  138 bits (348), Expect = 3e-32
 Identities = 119/445 (26%), Positives = 191/445 (42%), Gaps = 56/445 (12%)

Query: 183 VVDLDGKSSLLYRFDQKSLSPIKDIISLKFKTMQSDGILLHREGPNGDHITLQLRRARLF 242
           V    G     Y      +    D I+L F+T+Q +G++LH  G + D++ L L+   ++
Sbjct: 265 VATFKGNEFFCYDLSHNPIQSSTDEITLAFRTLQRNGLMLHT-GKSADYVNLSLKSGAVW 323

Query: 243 LLINSGEAKLPSTSTLVNLTLGSLLDDQHWHSVLIQRLGKQ--------VNFTVDEHRHH 294
           L+IN G     +    VN       +D  WH V + R  +Q        V  +VD     
Sbjct: 324 LVINLGSGAFEALVEPVN----GKFNDNAWHDVRVTRNLRQHAGIGHAMVTISVDGILTT 379

Query: 295 F-HARGEFNLMNLDYEISFGGIP----APGKSVSFPHRNFHGCLENLYYNGVD----IID 345
             + + ++ ++  D     GG P     PG  VS    NF GCL+++ Y   D    +  
Sbjct: 380 TGYTQEDYTMLGSDDFFYIGGSPNTADLPGSPVS---NNFMGCLKDVVYKNNDFKLELSR 436

Query: 346 LAKQQKPQIIAMGNVSFSCSQPQSM-PVTFLSSRSYLALPDFSGEEEVSATFQFRTWNKA 404
           LAK+  P++   G++SF C    ++ PVTF S  +++ALP +S +   S +  FRT    
Sbjct: 437 LAKEGDPKMKLQGDLSFRCEDVAALDPVTFESPEAFVALPRWSAKRTGSISLDFRTTEPN 496

Query: 405 GLLLFSELQLISGG------------ILLFLSDGKLKSNLYQPGKLPSDITAGVELNDGQ 452
           GLLLFS+ +   GG              + L DG L   L           +  ++NDG+
Sbjct: 497 GLLLFSQGRRAGGGAGSHSSAQRADYFAMELLDGHLYLLLDMGSGGIKLRASSRKVNDGE 556

Query: 453 WHSVSLSAKKNHLSVAVDGQMASAAPLLGPEQIYSGGTYYFGGCPDKSFGSKCKSPL--- 509
           W  V         S++V+ +          E +      Y GG P+   G +   PL   
Sbjct: 557 WCHVDFQRDGRKGSISVNSRSTPFLATGDSEILDLESELYLGGLPE---GGRVDLPLPPE 613

Query: 510 -------GGFQGCMRLISISGKVVDL--ISVQQGSLGNFSDLQIDSCGISDRCLPNYCEH 560
                   G+ GC+R + I G+  DL  ++  QG++G       ++     +C    C +
Sbjct: 614 VWTAALRAGYVGCVRDLFIDGRSRDLRGLAEAQGAVGVAPFCSRETL---KQCASAPCRN 670

Query: 561 GGECSQSWSTFHCNCTNTGYRGATC 585
           GG C + W+ F C+C  TG+ G  C
Sbjct: 671 GGVCREGWNRFICDCIGTGFLGRVC 695



 Score =  131 bits (330), Expect = 4e-30
 Identities = 112/426 (26%), Positives = 175/426 (41%), Gaps = 41/426 (9%)

Query: 177  CAYRSEVVDLDGKSSLLYRFDQKSLSPIKDIISLKFKTMQSDGILLHREG-PNGDHITLQ 235
            C   + V+  DG   +         +  +D+ SL+F + ++ G+++      + D + L+
Sbjct: 695  CEREATVLSYDGSMYMKIMLPNAMHTEAEDV-SLRFMSQRAYGLMMATTSRESADTLRLE 753

Query: 236  LRRARLFLLINSGEAKLPSTSTLVNLTLGSLLDDQHWHSVLIQRLGKQVNFTVDEHRHHF 295
            L   ++ L +N G+   P T     L  G  L+D  WH+V + R GK +  +VD      
Sbjct: 754  LDGGQMKLTVNLGKG--PET-----LFAGHKLNDNEWHTVRVVRRGKSLQLSVDNVTVEG 806

Query: 296  HARGEFNLMNLDYEISFGGIPAPGKSVSFPHRNFHGCLENLYYNGVDIIDLAKQQKPQII 355
               G    M L++     GI    + +S    NF G L  L +NG   +D  K       
Sbjct: 807  QMAGAH--MRLEFHNIETGIMTERRFISVVPSNFIGHLSGLVFNGQPYMDQCKDGDITYC 864

Query: 356  AMGNVSFSCSQPQSMPVTFLSSRSYLALPDFSGEEEVSATFQFRTWNKAGLLLFSE---- 411
             + N  F      + PVTF S  SYLAL        +   FQF+T    GLLLF+     
Sbjct: 865  EL-NARFGLRAIVADPVTFKSRSSYLALATLQAYASMHLFFQFKTTAPDGLLLFNSGNGN 923

Query: 412  ----LQLISGGILLFLSDGK----LKSNLYQPGKLPSDITAGVELNDGQWHSVSLSAKKN 463
                ++L+ G I      G     +K N  +P            +ND QWH+V +S    
Sbjct: 924  DFIVIELVKGYIHYVFDLGNGPSLMKGNSDKP------------VNDNQWHNVVVSRDPG 971

Query: 464  HLSVAVDGQMASAAPLLGPEQIYSGGTYYFGGCPDKSFGS--KCKSPLGGFQGCMRLISI 521
            ++               G   +   G  Y GG     F +  K  +   GFQGC+  + +
Sbjct: 972  NVHTLKIDSRTVTQHSNGARNLDLKGELYIGGLSKNMFSNLPKLVASRDGFQGCLASVDL 1031

Query: 522  SGKVVDLISVQQGSLGNFSDLQIDSCGISDRCLPNYCEHGGECSQSWSTFHCNCTNTGYR 581
            +G++ DLI+    +L     ++    G S  C    C + G C Q W  F C+CT T Y 
Sbjct: 1032 NGRLPDLIA---DALHRIGQVERGCDGPSTTCTEESCANQGVCLQQWDGFTCDCTMTSYG 1088

Query: 582  GATCHN 587
            G  C++
Sbjct: 1089 GPVCND 1094



 Score =  116 bits (291), Expect = 1e-25
 Identities = 99/343 (28%), Positives = 159/343 (46%), Gaps = 39/343 (11%)

Query: 796  SFDTEASYLHFPTFHGELSADVSFFFKTTASSGVFLENLGIA-DFIRIELRSPTVVTFSF 854
            +F + +SYL   T     S  + F FKTTA  G+ L N G   DFI IEL     + + F
Sbjct: 881  TFKSRSSYLALATLQAYASMHLFFQFKTTAPDGLLLFNSGNGNDFIVIELVKG-YIHYVF 939

Query: 855  DVGNGPFEISVQSPTHFNDNQWHHVRVERNMKEA-SLQVDQLTPKTQPAPADGHVLLQLN 913
            D+GNGP  +   S    NDNQWH+V V R+     +L++D    +T    ++G   L L 
Sbjct: 940  DLGNGPSLMKGNSDKPVNDNQWHNVVVSRDPGNVHTLKIDS---RTVTQHSNGARNLDLK 996

Query: 914  SQLFVGGTATR-----------QRGFLGCIRSLQLNGMTLDL-EERAQVTPEVQPGCRGH 961
             +L++GG +             + GF GC+ S+ LNG   DL  +      +V+ GC G 
Sbjct: 997  GELYIGGLSKNMFSNLPKLVASRDGFQGCLASVDLNGRLPDLIADALHRIGQVERGCDGP 1056

Query: 962  CSSYGK-LCRNGGKCRERPIGFFCDCTFSAYTGPFCSNEISAY-FGSGSSVIYNFQENYL 1019
             ++  +  C N G C ++  GF CDCT ++Y GP C++  + Y FG G ++I      Y 
Sbjct: 1057 STTCTEESCANQGVCLQQWDGFTCDCTMTSYGGPVCNDPGTTYIFGKGGALI-----TYT 1111

Query: 1020 LSKNSSSHAASFHGDMKLSREMIKFSFRTTRTPSLLLFVSSFYKEYLSVIIAKNGSLQIR 1079
               N            ++ R  + FS        + +  +S   +YL + I   G++ + 
Sbjct: 1112 WPPND-------RPSTRMDRLAVGFSTHQRSAVLVRVDSASGLGDYLQLHI-DQGTVGVI 1163

Query: 1080 YKLNKYQEPDVVNFDFKN--MADGQLHHIMINREEGVVFIEID 1120
            + +      D +  D  N  ++DG+ H +   R  G   +++D
Sbjct: 1164 FNVG----TDDITIDEPNAIVSDGKYHVVRFTRSGGNATLQVD 1202



 Score =  103 bits (258), Expect = 8e-22
 Identities = 180/819 (21%), Positives = 310/819 (37%), Gaps = 163/819 (19%)

Query: 395  TFQFRTWNKAGLLLFSELQLISGG----ILLFLSDGKLKSNLYQPGKLPSDITAGVELND 450
            +F  RT     LLL+    L  GG    + L L DG+L+         P+ +     + D
Sbjct: 54   SFSLRTNATRALLLY----LDDGGDCDFLELLLVDGRLRLRFTLSCAEPATLQLDTPVAD 109

Query: 451  GQWHSVSLSAKKNHLSVAVDGQMASAAPLLGPEQIYSGGTYYFGGCP-DKSFGSKCKSPL 509
             +WH V L+      ++AVDG+  +A       ++      + GG P D    +   S +
Sbjct: 110  DRWHMVLLTRDARRTALAVDGEARAAEVRSKRREMQVASDLFVGGIPPDVRLSALTLSTV 169

Query: 510  G---GFQGCMRLISISGKVVDLISVQQGSLGNFSDLQIDSCGISDRCLP--NYCEHGGEC 564
                 F+G +  + +  +   L+   QG  G  +D           C P  N C +GG C
Sbjct: 170  KYEPPFRGLLANLKLGERPPALLG-SQGLRGATAD---------PLCAPARNPCANGGLC 219

Query: 565  SQ-SWSTFHCNCTNTGYRGATC-----------HNSIYEQSCEAYKHRGNTSGFYYIDSD 612
            +  +     C+C++TG+ G  C           H ++  +  E +      + F+  D  
Sbjct: 220  TVLAPGEVGCDCSHTGFGGKFCSEEEHPMEGPAHLTLNSEGKEEFVATFKGNEFFCYDLS 279

Query: 613  GSGPLEPFLLYCNMTETAWTIIQHNGSDLTRVRNTNPENPY-------------AGFFEY 659
             +    P     +    A+  +Q NG  L   ++ +  N               +G FE 
Sbjct: 280  HN----PIQSSTDEITLAFRTLQRNGLMLHTGKSADYVNLSLKSGAVWLVINLGSGAFE- 334

Query: 660  VASMEQLQATINRAEHCEQEFTYYCKK------SRLVNKQDGTPLSWWVGRTNETQTYWG 713
             A +E +    N     +   T   ++      + +    DG   +   G T E  T  G
Sbjct: 335  -ALVEPVNGKFNDNAWHDVRVTRNLRQHAGIGHAMVTISVDGILTT--TGYTQEDYTMLG 391

Query: 714  -------GSSPDLQKCTCGLEGNCIDSQYYCNCDADRNEWTNDTGLLAYKEHLPVTKIVI 766
                   G SP+    T  L G+ + S  +  C  D     ND  L              
Sbjct: 392  SDDFFYIGGSPN----TADLPGSPV-SNNFMGCLKDVVYKNNDFKL-------------- 432

Query: 767  TDTGRLHSEAAYKLGPLLCQGDRSF-------WNSASFDTEASYLHFPTFHGELSADVSF 819
             +  RL  E   K+     QGD SF        +  +F++  +++  P +  + +  +S 
Sbjct: 433  -ELSRLAKEGDPKMK---LQGDLSFRCEDVAALDPVTFESPEAFVALPRWSAKRTGSISL 488

Query: 820  FFKTTASSGVFLENLGI--------------ADFIRIELRSPTVVTFSFDVGNGPFEISV 865
             F+TT  +G+ L + G               AD+  +EL    +     D+G+G  ++  
Sbjct: 489  DFRTTEPNGLLLFSQGRRAGGGAGSHSSAQRADYFAMELLDGHLYLL-LDMGSGGIKLRA 547

Query: 866  QSPTHFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHV-LLQLNSQLFVGG---- 920
             S    ND +W HV  +R+ ++ S+ V+    ++ P  A G   +L L S+L++GG    
Sbjct: 548  SS-RKVNDGEWCHVDFQRDGRKGSISVNS---RSTPFLATGDSEILDLESELYLGGLPEG 603

Query: 921  ------------TATRQRGFLGCIRSLQLNGMTLDLE--ERAQVTPEVQPGCRGH----C 962
                        TA  + G++GC+R L ++G + DL     AQ    V P C       C
Sbjct: 604  GRVDLPLPPEVWTAALRAGYVGCVRDLFIDGRSRDLRGLAEAQGAVGVAPFCSRETLKQC 663

Query: 963  SSYGKLCRNGGKCRERPIGFFCDCTFSAYTGPFCSNEISAYFGSGSSVIYNFQENYLLSK 1022
            +S    CRNGG CRE    F CDC  + + G  C  E +     GS  +     N     
Sbjct: 664  ASAP--CRNGGVCREGWNRFICDCIGTGFLGRVCEREATVLSYDGSMYMKIMLPN----- 716

Query: 1023 NSSSHAASFHGDMKLSREMIKFSFRTTRTPSLLLFVSSFYKEYLSVIIAKNGSLQIRYKL 1082
                        M    E +   F + R   L++  +S  +E    +  +    Q++  +
Sbjct: 717  -----------AMHTEAEDVSLRFMSQRAYGLMMATTS--RESADTLRLELDGGQMKLTV 763

Query: 1083 NKYQEPDVVNFDFKNMADGQLHHIMINREEGVVFIEIDD 1121
            N  + P+ + F    + D + H + + R    + + +D+
Sbjct: 764  NLGKGPETL-FAGHKLNDNEWHTVRVVRRGKSLQLSVDN 801



 Score = 71.2 bits (173), Expect = 6e-12
 Identities = 95/382 (24%), Positives = 153/382 (40%), Gaps = 74/382 (19%)

Query: 816  DVSFFFKTTASSGVFLENLG--IADFIRIELRSPTVVTFSFDVGNGPFEISVQSPTHFND 873
            DVS  F +  + G+ +       AD +R+EL    +   + ++G GP  +        ND
Sbjct: 724  DVSLRFMSQRAYGLMMATTSRESADTLRLELDGGQM-KLTVNLGKGPETLFAGHK--LND 780

Query: 874  NQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFVGGTATRQR------- 926
            N+WH VRV R  K   L VD +T + Q A A  H+ L+ ++     G  T +R       
Sbjct: 781  NEWHTVRVVRRGKSLQLSVDNVTVEGQMAGA--HMRLEFHN--IETGIMTERRFISVVPS 836

Query: 927  GFLGCIRSLQLNGMTLDLEERAQVTPEVQPGCRGHCSSYGKLCRNGGKCRERPIGFFCDC 986
             F+G +  L  NG               QP        Y   C++G            D 
Sbjct: 837  NFIGHLSGLVFNG---------------QP--------YMDQCKDG------------DI 861

Query: 987  TFSAYTGPFCSNEISAYFGSGSSVIYNFQENYLLSKNSSSHAASFHGDMKLSREMIKFSF 1046
            T+      F    I A       V +  + +YL      ++A S H         + F F
Sbjct: 862  TYCELNARFGLRAIVA-----DPVTFKSRSSYLALATLQAYA-SMH---------LFFQF 906

Query: 1047 RTTRTPSLLLFVSSFYKEYLSVIIAKNGSLQIRYKLNKYQEPDVV--NFDFKNMADGQLH 1104
            +TT    LLLF S    +++ + + K     I Y  +    P ++  N D K + D Q H
Sbjct: 907  KTTAPDGLLLFNSGNGNDFIVIELVKG---YIHYVFDLGNGPSLMKGNSD-KPVNDNQWH 962

Query: 1105 HIMINREEGVVFIEIDDNRRRQVHLSSGTEFSAVKSLVLGRILEHSDVDQDTALAGAQGF 1164
            +++++R+ G V     D+R    H +          L +G + ++   +    +A   GF
Sbjct: 963  NVVVSRDPGNVHTLKIDSRTVTQHSNGARNLDLKGELYIGGLSKNMFSNLPKLVASRDGF 1022

Query: 1165 TGCLSAVQLSHVAP--LKAALH 1184
             GCL++V L+   P  +  ALH
Sbjct: 1023 QGCLASVDLNGRLPDLIADALH 1044



 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 63/268 (23%), Positives = 108/268 (40%), Gaps = 38/268 (14%)

Query: 814  SADVSFFFKTTASSGV--FLENLGIADFIRIELRSPTV-VTFSFDVGNGPFEISVQSPTH 870
            S ++SF  +T A+  +  +L++ G  DF+ + L    + + F+          ++Q  T 
Sbjct: 50   SGELSFSLRTNATRALLLYLDDGGDCDFLELLLVDGRLRLRFTLSCAE---PATLQLDTP 106

Query: 871  FNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFVGG---------- 920
              D++WH V + R+ +  +L VD      +         +Q+ S LFVGG          
Sbjct: 107  VADDRWHMVLLTRDARRTALAVDGEARAAEVRSKRRE--MQVASDLFVGGIPPDVRLSAL 164

Query: 921  ---TATRQRGFLGCIRSLQLNGMTLDLEERAQVTPEVQPGCRGH-----CSSYGKLCRNG 972
               T   +  F G + +L+L        ER       Q G RG      C+     C NG
Sbjct: 165  TLSTVKYEPPFRGLLANLKLG-------ERPPALLGSQ-GLRGATADPLCAPARNPCANG 216

Query: 973  GKCRERPIGFF-CDCTFSAYTGPFCSNEISAYFGSGSSVIYNFQENYLLSKNSSSHAASF 1031
            G C     G   CDC+ + + G FCS E     G     + +  +   ++    +    +
Sbjct: 217  GLCTVLAPGEVGCDCSHTGFGGKFCSEEEHPMEGPAHLTLNSEGKEEFVATFKGNEFFCY 276

Query: 1032 ---HGDMKLSREMIKFSFRTTRTPSLLL 1056
               H  ++ S + I  +FRT +   L+L
Sbjct: 277  DLSHNPIQSSTDEITLAFRTLQRNGLML 304



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 35/159 (22%), Positives = 65/159 (40%), Gaps = 18/159 (11%)

Query: 206  DIISLKFKTMQSDGILLHREGPNG--DHITLQLRRARLFLLINSGEAKLPSTSTLVNLTL 263
            D +++ F T Q   +L+  +  +G  D++ L + +  + ++ N G      T  +     
Sbjct: 1123 DRLAVGFSTHQRSAVLVRVDSASGLGDYLQLHIDQGTVGVIFNVG------TDDITIDEP 1176

Query: 264  GSLLDDQHWHSVLIQRLGKQVNFTVDEH--RHHFHARGEFNLMNLDYEISFGGIPAPGKS 321
             +++ D  +H V   R G      VD       + A  +  + N    I  GG       
Sbjct: 1177 NAIVSDGKYHVVRFTRSGGNATLQVDSWPVNERYPAGRQLTIFNSQAAIKIGGRDQG--- 1233

Query: 322  VSFPHRNFHGCLENLYYNGVDIIDLAKQQKPQIIAMGNV 360
                 R F G +  LYYNG+ ++ LA +  P +   G++
Sbjct: 1234 -----RPFQGQVSGLYYNGLKVLALAAESDPNVRTEGHL 1267



 Score = 38.9 bits (89), Expect = 0.033
 Identities = 95/436 (21%), Positives = 160/436 (36%), Gaps = 101/436 (23%)

Query: 162 WNPKGRIGMRIEVFGCAYRSEVVDLDGKSSLLYRFDQKSLSPIKDIISLKFKTMQSDGIL 221
           W P     + + +   A R++ ++  G      R+ + + +     +S   +T  +  +L
Sbjct: 7   WRPTPPPLLLLLLLALAARADGLEFGGGPGQWARYARWAGAASSGELSFSLRTNATRALL 66

Query: 222 LHRE-GPNGDHITLQLRRARLFLLINSGEAKLPSTSTLVNLTLGSLLDDQHWHSVLIQRL 280
           L+ + G + D + L L   RL L      A+ P+T     L L + + D  WH VL+ R 
Sbjct: 67  LYLDDGGDCDFLELLLVDGRLRLRFTLSCAE-PAT-----LQLDTPVADDRWHMVLLTRD 120

Query: 281 GKQVNFTVDEHRHHFHARGEFNLMNLDYEISFGGIP------APGKSVSFPHRNFHGCLE 334
            ++    VD        R +   M +  ++  GGIP      A   S       F G L 
Sbjct: 121 ARRTALAVDGEARAAEVRSKRREMQVASDLFVGGIPPDVRLSALTLSTVKYEPPFRGLLA 180

Query: 335 NLY-------------YNGVDIIDL-AKQQKP-------QIIAMGNVSFSCSQPQ----- 368
           NL                G     L A  + P        ++A G V   CS        
Sbjct: 181 NLKLGERPPALLGSQGLRGATADPLCAPARNPCANGGLCTVLAPGEVGCDCSHTGFGGKF 240

Query: 369 -SMPVTFLSSRSYLALPDFSGEEEVSATFQ------------------------FRTWNK 403
            S     +   ++L L +  G+EE  ATF+                        FRT  +
Sbjct: 241 CSEEEHPMEGPAHLTL-NSEGKEEFVATFKGNEFFCYDLSHNPIQSSTDEITLAFRTLQR 299

Query: 404 AGLLL-------FSELQLISGGILLFLSDGKLKSNLYQPGKLPSDITAGVELNDGQWHSV 456
            GL+L       +  L L SG + L ++   L S  ++    P       + ND  WH V
Sbjct: 300 NGLMLHTGKSADYVNLSLKSGAVWLVIN---LGSGAFEALVEP----VNGKFNDNAWHDV 352

Query: 457 SLSAK-KNH-------LSVAVDGQMASAA------PLLGPEQIYSGGTYYFGGCPDKSFG 502
            ++   + H       ++++VDG + +         +LG +       +Y GG P+ +  
Sbjct: 353 RVTRNLRQHAGIGHAMVTISVDGILTTTGYTQEDYTMLGSDDF-----FYIGGSPNTA-- 405

Query: 503 SKCKSPL-GGFQGCMR 517
               SP+   F GC++
Sbjct: 406 DLPGSPVSNNFMGCLK 421


>gi|14211536 neurexin 2 isoform alpha-1 precursor [Homo sapiens]
          Length = 1712

 Score =  137 bits (346), Expect = 5e-32
 Identities = 117/452 (25%), Positives = 191/452 (42%), Gaps = 63/452 (13%)

Query: 183 VVDLDGKSSLLYRFDQKSLSPIKDIISLKFKTMQSDGILLHREGPNGDHITLQLRRARLF 242
           V    G     Y      +    D I+L F+T+Q +G++LH  G + D++ L L+   ++
Sbjct: 289 VATFKGNEFFCYDLSHNPIQSSTDEITLAFRTLQRNGLMLHT-GKSADYVNLSLKSGAVW 347

Query: 243 LLINSGEAKLPSTSTLVNLTLGSLLDDQHWHSVLIQRLGKQ---VNFTVDEHRHHF---- 295
           L+IN G     +    VN       +D  WH V + R  +Q   +   +    H+     
Sbjct: 348 LVINLGSGAFEALVEPVN----GKFNDNAWHDVRVTRNLRQHAGIGHAMVNKLHYLVTIS 403

Query: 296 ---------HARGEFNLMNLDYEISFGGIP----APGKSVSFPHRNFHGCLENLYYNGVD 342
                    + + ++ ++  D     GG P     PG  VS    NF GCL+++ Y   D
Sbjct: 404 VDGILTTTGYTQEDYTMLGSDDFFYIGGSPNTADLPGSPVS---NNFMGCLKDVVYKNND 460

Query: 343 ----IIDLAKQQKPQIIAMGNVSFSCSQPQSM-PVTFLSSRSYLALPDFSGEEEVSATFQ 397
               +  LAK+  P++   G++SF C    ++ PVTF S  +++ALP +S +   S +  
Sbjct: 461 FKLELSRLAKEGDPKMKLQGDLSFRCEDVAALDPVTFESPEAFVALPRWSAKRTGSISLD 520

Query: 398 FRTWNKAGLLLFSELQLISGG------------ILLFLSDGKLKSNLYQPGKLPSDITAG 445
           FRT    GLLLFS+ +   GG              + L DG L   L           + 
Sbjct: 521 FRTTEPNGLLLFSQGRRAGGGAGSHSSAQRADYFAMELLDGHLYLLLDMGSGGIKLRASS 580

Query: 446 VELNDGQWHSVSLSAKKNHLSVAVDGQMASAAPLLGPEQIYSGGTYYFGGCPDKSFGSKC 505
            ++NDG+W  V         S++V+ +          E +      Y GG P+   G + 
Sbjct: 581 RKVNDGEWCHVDFQRDGRKGSISVNSRSTPFLATGDSEILDLESELYLGGLPE---GGRV 637

Query: 506 KSPL----------GGFQGCMRLISISGKVVDL--ISVQQGSLGNFSDLQIDSCGISDRC 553
             PL           G+ GC+R + I G+  DL  ++  QG++G       ++     +C
Sbjct: 638 DLPLPPEVWTAALRAGYVGCVRDLFIDGRSRDLRGLAEAQGAVGVAPFCSRETL---KQC 694

Query: 554 LPNYCEHGGECSQSWSTFHCNCTNTGYRGATC 585
               C +GG C + W+ F C+C  TG+ G  C
Sbjct: 695 ASAPCRNGGVCREGWNRFICDCIGTGFLGRVC 726



 Score =  127 bits (320), Expect = 5e-29
 Identities = 112/433 (25%), Positives = 175/433 (40%), Gaps = 46/433 (10%)

Query: 177  CAYRSEVVDLDGKSSLLYRFDQKSLSPIKDIISLKFKTMQSDGILLHREG-PNGDHITLQ 235
            C   + V+  DG   +         +  +D+ SL+F + ++ G+++      + D + L+
Sbjct: 726  CEREATVLSYDGSMYMKIMLPNAMHTEAEDV-SLRFMSQRAYGLMMATTSRESADTLRLE 784

Query: 236  LRRARLFLLIN-------SGEAKLPSTSTLVNLTLGSLLDDQHWHSVLIQRLGKQVNFTV 288
            L   ++ L +N          +K P T     L  G  L+D  WH+V + R GK +  +V
Sbjct: 785  LDGGQMKLTVNLDCLRVGCAPSKGPET-----LFAGHKLNDNEWHTVRVVRRGKSLQLSV 839

Query: 289  DEHRHHFHARGEFNLMNLDYEISFGGIPAPGKSVSFPHRNFHGCLENLYYNGVDIIDLAK 348
            D         G    M L++     GI    + +S    NF G L  L +NG   +D  K
Sbjct: 840  DNVTVEGQMAGAH--MRLEFHNIETGIMTERRFISVVPSNFIGHLSGLVFNGQPYMDQCK 897

Query: 349  QQKPQIIAMGNVSFSCSQPQSMPVTFLSSRSYLALPDFSGEEEVSATFQFRTWNKAGLLL 408
                    + N  F      + PVTF S  SYLAL        +   FQF+T    GLLL
Sbjct: 898  DGDITYCEL-NARFGLRAIVADPVTFKSRSSYLALATLQAYASMHLFFQFKTTAPDGLLL 956

Query: 409  FSE--------LQLISGGILLFLSDGK----LKSNLYQPGKLPSDITAGVELNDGQWHSV 456
            F+         ++L+ G I      G     +K N  +P            +ND QWH+V
Sbjct: 957  FNSGNGNDFIVIELVKGYIHYVFDLGNGPSLMKGNSDKP------------VNDNQWHNV 1004

Query: 457  SLSAKKNHLSVAVDGQMASAAPLLGPEQIYSGGTYYFGGCPDKSFGS--KCKSPLGGFQG 514
             +S    ++               G   +   G  Y GG     F +  K  +   GFQG
Sbjct: 1005 VVSRDPGNVHTLKIDSRTVTQHSNGARNLDLKGELYIGGLSKNMFSNLPKLVASRDGFQG 1064

Query: 515  CMRLISISGKVVDLISVQQGSLGNFSDLQIDSCGISDRCLPNYCEHGGECSQSWSTFHCN 574
            C+  + ++G++ DLI+    +L     ++    G S  C    C + G C Q W  F C+
Sbjct: 1065 CLASVDLNGRLPDLIA---DALHRIGQVERGCDGPSTTCTEESCANQGVCLQQWDGFTCD 1121

Query: 575  CTNTGYRGATCHN 587
            CT T Y G  C++
Sbjct: 1122 CTMTSYGGPVCND 1134



 Score =  116 bits (291), Expect = 1e-25
 Identities = 99/343 (28%), Positives = 159/343 (46%), Gaps = 39/343 (11%)

Query: 796  SFDTEASYLHFPTFHGELSADVSFFFKTTASSGVFLENLGIA-DFIRIELRSPTVVTFSF 854
            +F + +SYL   T     S  + F FKTTA  G+ L N G   DFI IEL     + + F
Sbjct: 921  TFKSRSSYLALATLQAYASMHLFFQFKTTAPDGLLLFNSGNGNDFIVIELVKG-YIHYVF 979

Query: 855  DVGNGPFEISVQSPTHFNDNQWHHVRVERNMKEA-SLQVDQLTPKTQPAPADGHVLLQLN 913
            D+GNGP  +   S    NDNQWH+V V R+     +L++D    +T    ++G   L L 
Sbjct: 980  DLGNGPSLMKGNSDKPVNDNQWHNVVVSRDPGNVHTLKIDS---RTVTQHSNGARNLDLK 1036

Query: 914  SQLFVGGTATR-----------QRGFLGCIRSLQLNGMTLDL-EERAQVTPEVQPGCRGH 961
             +L++GG +             + GF GC+ S+ LNG   DL  +      +V+ GC G 
Sbjct: 1037 GELYIGGLSKNMFSNLPKLVASRDGFQGCLASVDLNGRLPDLIADALHRIGQVERGCDGP 1096

Query: 962  CSSYGK-LCRNGGKCRERPIGFFCDCTFSAYTGPFCSNEISAY-FGSGSSVIYNFQENYL 1019
             ++  +  C N G C ++  GF CDCT ++Y GP C++  + Y FG G ++I      Y 
Sbjct: 1097 STTCTEESCANQGVCLQQWDGFTCDCTMTSYGGPVCNDPGTTYIFGKGGALI-----TYT 1151

Query: 1020 LSKNSSSHAASFHGDMKLSREMIKFSFRTTRTPSLLLFVSSFYKEYLSVIIAKNGSLQIR 1079
               N            ++ R  + FS        + +  +S   +YL + I   G++ + 
Sbjct: 1152 WPPND-------RPSTRMDRLAVGFSTHQRSAVLVRVDSASGLGDYLQLHI-DQGTVGVI 1203

Query: 1080 YKLNKYQEPDVVNFDFKN--MADGQLHHIMINREEGVVFIEID 1120
            + +      D +  D  N  ++DG+ H +   R  G   +++D
Sbjct: 1204 FNVG----TDDITIDEPNAIVSDGKYHVVRFTRSGGNATLQVD 1242



 Score = 86.3 bits (212), Expect = 2e-16
 Identities = 73/267 (27%), Positives = 119/267 (44%), Gaps = 51/267 (19%)

Query: 786  QGDRSF-------WNSASFDTEASYLHFPTFHGELSADVSFFFKTTASSGVFLENLGI-- 836
            QGD SF        +  +F++  +++  P +  + +  +S  F+TT  +G+ L + G   
Sbjct: 479  QGDLSFRCEDVAALDPVTFESPEAFVALPRWSAKRTGSISLDFRTTEPNGLLLFSQGRRA 538

Query: 837  ------------ADFIRIELRSPTVVTFSFDVGNGPFEISVQSPTHFNDNQWHHVRVERN 884
                        AD+  +EL    +     D+G+G  ++   S    ND +W HV  +R+
Sbjct: 539  GGGAGSHSSAQRADYFAMELLDGHLYLL-LDMGSGGIKLRASS-RKVNDGEWCHVDFQRD 596

Query: 885  MKEASLQVDQLTPKTQPAPADGHV-LLQLNSQLFVGG----------------TATRQRG 927
             ++ S+ V+    ++ P  A G   +L L S+L++GG                TA  + G
Sbjct: 597  GRKGSISVNS---RSTPFLATGDSEILDLESELYLGGLPEGGRVDLPLPPEVWTAALRAG 653

Query: 928  FLGCIRSLQLNGMTLDLE--ERAQVTPEVQPGCRGH----CSSYGKLCRNGGKCRERPIG 981
            ++GC+R L ++G + DL     AQ    V P C       C+S    CRNGG CRE    
Sbjct: 654  YVGCVRDLFIDGRSRDLRGLAEAQGAVGVAPFCSRETLKQCASAP--CRNGGVCREGWNR 711

Query: 982  FFCDCTFSAYTGPFCSNEISAYFGSGS 1008
            F CDC  + + G  C  E +     GS
Sbjct: 712  FICDCIGTGFLGRVCEREATVLSYDGS 738



 Score = 67.8 bits (164), Expect = 7e-11
 Identities = 97/388 (25%), Positives = 157/388 (40%), Gaps = 77/388 (19%)

Query: 816  DVSFFFKTTASSGVFLENLG--IADFIRIELRSPTV-VTFSFD---VGNGPFE--ISVQS 867
            DVS  F +  + G+ +       AD +R+EL    + +T + D   VG  P +   ++ +
Sbjct: 755  DVSLRFMSQRAYGLMMATTSRESADTLRLELDGGQMKLTVNLDCLRVGCAPSKGPETLFA 814

Query: 868  PTHFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFVGGTATRQR- 926
                NDN+WH VRV R  K   L VD +T + Q A A  H+ L+ ++     G  T +R 
Sbjct: 815  GHKLNDNEWHTVRVVRRGKSLQLSVDNVTVEGQMAGA--HMRLEFHN--IETGIMTERRF 870

Query: 927  ------GFLGCIRSLQLNGMTLDLEERAQVTPEVQPGCRGHCSSYGKLCRNGGKCRERPI 980
                   F+G +  L  NG               QP        Y   C++G        
Sbjct: 871  ISVVPSNFIGHLSGLVFNG---------------QP--------YMDQCKDG-------- 899

Query: 981  GFFCDCTFSAYTGPFCSNEISAYFGSGSSVIYNFQENYLLSKNSSSHAASFHGDMKLSRE 1040
                D T+      F    I A       V +  + +YL      ++A S H        
Sbjct: 900  ----DITYCELNARFGLRAIVA-----DPVTFKSRSSYLALATLQAYA-SMH-------- 941

Query: 1041 MIKFSFRTTRTPSLLLFVSSFYKEYLSVIIAKNGSLQIRYKLNKYQEPDVV--NFDFKNM 1098
             + F F+TT    LLLF S    +++ + + K     I Y  +    P ++  N D K +
Sbjct: 942  -LFFQFKTTAPDGLLLFNSGNGNDFIVIELVKG---YIHYVFDLGNGPSLMKGNSD-KPV 996

Query: 1099 ADGQLHHIMINREEGVVFIEIDDNRRRQVHLSSGTEFSAVKSLVLGRILEHSDVDQDTAL 1158
             D Q H+++++R+ G V     D+R    H +          L +G + ++   +    +
Sbjct: 997  NDNQWHNVVVSRDPGNVHTLKIDSRTVTQHSNGARNLDLKGELYIGGLSKNMFSNLPKLV 1056

Query: 1159 AGAQGFTGCLSAVQLSHVAP--LKAALH 1184
            A   GF GCL++V L+   P  +  ALH
Sbjct: 1057 ASRDGFQGCLASVDLNGRLPDLIADALH 1084



 Score = 50.8 bits (120), Expect = 8e-06
 Identities = 37/154 (24%), Positives = 67/154 (43%), Gaps = 26/154 (16%)

Query: 816 DVSFFFKTTASSGVFLENLGIADFIRIELRSPTVVTFSFDVGNGPFEISVQSPT-HFNDN 874
           +++  F+T   +G+ L     AD++ + L+S  V     ++G+G FE  V+     FNDN
Sbjct: 313 EITLAFRTLQRNGLMLHTGKSADYVNLSLKSGAV-WLVINLGSGAFEALVEPVNGKFNDN 371

Query: 875 QWHHVRVERNMKE---------------ASLQVDQLTPKTQPAPADGHVLLQLNSQLFVG 919
            WH VRV RN+++                ++ VD +   T     D + +L  +   ++G
Sbjct: 372 AWHDVRVTRNLRQHAGIGHAMVNKLHYLVTISVDGILTTTGYTQED-YTMLGSDDFFYIG 430

Query: 920 GTATR--------QRGFLGCIRSLQLNGMTLDLE 945
           G+              F+GC++ +        LE
Sbjct: 431 GSPNTADLPGSPVSNNFMGCLKDVVYKNNDFKLE 464



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 54/208 (25%), Positives = 86/208 (41%), Gaps = 35/208 (16%)

Query: 814 SADVSFFFKTTASSGV--FLENLGIADFIRIELRSPTV-VTFSFDVGNGPFEISVQSPTH 870
           S ++SF  +T A+  +  +L++ G  DF+ + L    + + F+          ++Q  T 
Sbjct: 50  SGELSFSLRTNATRALLLYLDDGGDCDFLELLLVDGRLRLRFTLSCAE---PATLQLDTP 106

Query: 871 FNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFVGG---------- 920
             D++WH V + R+ +  +L VD      +         +Q+ S LFVGG          
Sbjct: 107 VADDRWHMVLLTRDARRTALAVDGEARAAEVRSKRRE--MQVASDLFVGGIPPDVRLSAL 164

Query: 921 ---TATRQRGFLGCIRSLQLNGMTLDLEERAQVTPEVQPGCRGH-----CSSYGKLCRNG 972
              T   +  F G + +L+L        ER       Q G RG      C+     C NG
Sbjct: 165 TLSTVKYEPPFRGLLANLKLG-------ERPPALLGSQ-GLRGATADPLCAPARNPCANG 216

Query: 973 GKCRERPIGFF-CDCTFSAYTGPFCSNE 999
           G C     G   CDC+ + + G FCS E
Sbjct: 217 GLCTVLAPGEVGCDCSHTGFGGKFCSEE 244



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 54/232 (23%), Positives = 91/232 (39%), Gaps = 25/232 (10%)

Query: 395 TFQFRTWNKAGLLLFSELQLISGG----ILLFLSDGKLKSNLYQPGKLPSDITAGVELND 450
           +F  RT     LLL+    L  GG    + L L DG+L+         P+ +     + D
Sbjct: 54  SFSLRTNATRALLLY----LDDGGDCDFLELLLVDGRLRLRFTLSCAEPATLQLDTPVAD 109

Query: 451 GQWHSVSLSAKKNHLSVAVDGQMASAAPLLGPEQIYSGGTYYFGGC-PDKSFGSKCKSPL 509
            +WH V L+      ++AVDG+  +A       ++      + GG  PD    +   S +
Sbjct: 110 DRWHMVLLTRDARRTALAVDGEARAAEVRSKRREMQVASDLFVGGIPPDVRLSALTLSTV 169

Query: 510 ---GGFQGCMRLISISGKVVDLISVQQGSLGNFSDLQIDSCGISDRCLP--NYCEHGGEC 564
                F+G +  + +  +   L+   QG  G  +D           C P  N C +GG C
Sbjct: 170 KYEPPFRGLLANLKLGERPPALLG-SQGLRGATAD---------PLCAPARNPCANGGLC 219

Query: 565 S-QSWSTFHCNCTNTGYRGATCHNSIYEQSCEAYKHRGNTSGFYYIDSDGSG 615
           +  +     C+C++TG+ G  C    +     A+    +  G       G+G
Sbjct: 220 TVLAPGEVGCDCSHTGFGGKFCSEEEHPMEGPAHLTLNSEVGSLLFSEGGAG 271



 Score = 36.6 bits (83), Expect = 0.16
 Identities = 36/156 (23%), Positives = 66/156 (42%), Gaps = 7/156 (4%)

Query: 162 WNPKGRIGMRIEVFGCAYRSEVVDLDGKSSLLYRFDQKSLSPIKDIISLKFKTMQSDGIL 221
           W P     + + +   A R++ ++  G      R+ + + +     +S   +T  +  +L
Sbjct: 7   WRPTPPPLLLLLLLALAARADGLEFGGGPGQWARYARWAGAASSGELSFSLRTNATRALL 66

Query: 222 LHRE-GPNGDHITLQLRRARLFLLINSGEAKLPSTSTLVNLTLGSLLDDQHWHSVLIQRL 280
           L+ + G + D + L L   RL L      A+ P+T     L L + + D  WH VL+ R 
Sbjct: 67  LYLDDGGDCDFLELLLVDGRLRLRFTLSCAE-PAT-----LQLDTPVADDRWHMVLLTRD 120

Query: 281 GKQVNFTVDEHRHHFHARGEFNLMNLDYEISFGGIP 316
            ++    VD        R +   M +  ++  GGIP
Sbjct: 121 ARRTALAVDGEARAAEVRSKRREMQVASDLFVGGIP 156


>gi|14149613 neurexin 1 isoform alpha1 precursor [Homo sapiens]
          Length = 1477

 Score =  134 bits (338), Expect = 4e-31
 Identities = 115/454 (25%), Positives = 196/454 (43%), Gaps = 75/454 (16%)

Query: 183 VVDLDGKSSLLYRFDQKSLSPIKDIISLKFKTMQSDGILLHREGPNGDHITLQLRRARLF 242
           +    G     Y   Q  +    D I+L FKT+Q +G++LH  G + D++ L L+   + 
Sbjct: 283 IATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLHT-GKSADYVNLALKNGAVS 341

Query: 243 LLINSGEAKLPSTSTLVNLTLGSLLDDQHWHSVLIQRLGKQ--------VNFTVDEHRHH 294
           L+IN G     +    VN       +D  WH V + R  +Q        V  +VD     
Sbjct: 342 LVINLGSGAFEALVEPVN----GKFNDNAWHDVKVTRNLRQHSGIGHAMVTISVDGILTT 397

Query: 295 F-HARGEFNLMNLDYEISFGGIPA----PGKSVSFPHRNFHGCLENLYYNGVDI----ID 345
             + + ++ ++  D     GG P+    PG  VS    NF GCL+ + Y   D+      
Sbjct: 398 TGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVS---NNFMGCLKEVVYKNNDVRLELSR 454

Query: 346 LAKQQKPQIIAMGNVSFSCSQPQSM-PVTFLSSRSYLALPDFSGEEEVSATFQFRTWNKA 404
           LAKQ  P++   G V+F C    ++ P+TF +  S+++LP ++ ++  S +F FRT    
Sbjct: 455 LAKQGDPKMKIHGVVAFKCENVATLDPITFETPESFISLPKWNAKKTGSISFDFRTTEPN 514

Query: 405 GLLLFSE---------------------LQLISGGILLFLSDG----KLKSNLYQPGKLP 439
           GL+LFS                      ++++ G + L L  G    K+K+ L +     
Sbjct: 515 GLILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALLKK----- 569

Query: 440 SDITAGVELNDGQWHSVSLSAKKNHLSVAVDGQMASAAPLLGPEQIYSGGTYYFGGCPDK 499
                   +NDG+W+ V         +++V+            E +      Y GG P+ 
Sbjct: 570 --------VNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDLDDELYLGGLPEN 621

Query: 500 SFGSKCKSPLG------GFQGCMRLISISGKVVDLISVQQGSLGNFSDLQIDSCG--ISD 551
             G    + +       G+ GC+R + I G+  D+   Q   + + + ++  SC    + 
Sbjct: 622 KAGLVFPTEVWTALLNYGYVGCIRDLFIDGQSKDIR--QMAEVQSTAGVK-PSCSKETAK 678

Query: 552 RCLPNYCEHGGECSQSWSTFHCNCTNTGYRGATC 585
            CL N C++ G C   W+ + C+C+ TGY G +C
Sbjct: 679 PCLSNPCKNNGMCRDGWNRYVCDCSGTGYLGRSC 712



 Score =  131 bits (330), Expect = 4e-30
 Identities = 125/463 (26%), Positives = 206/463 (44%), Gaps = 61/463 (13%)

Query: 177  CAYRSEVVDLDGKSSLLYRFDQKSLSPIKDIISLKFKTMQSDGILLHREG-PNGDHITLQ 235
            C   + V+  DG   +  +      +  +D+ SL+F++ ++ GIL+      + D + L+
Sbjct: 712  CEREATVLSYDGSMFMKIQLPVVMHTEAEDV-SLRFRSQRAYGILMATTSRDSADTLRLE 770

Query: 236  LRRARLFLLINSGEAKLPSTSTLVNLTL--GSLLDDQHWHSVLIQRLGKQVNFTVDEHRH 293
            L   R+ L +N    ++   S+    TL  G  L+D  WH+V + R GK +  TVD+ + 
Sbjct: 771  LDAGRVKLTVNLDCIRINCNSSKGPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQA 830

Query: 294  HF------HARGEFNLMNLDYEISFGGIPAPGKSVSFPHRNFHGCLENLYYNGVDIIDLA 347
                    H R EF+ +         GI    + +S    NF G L++L +NG+  IDL 
Sbjct: 831  MTGQMAGDHTRLEFHNIET-------GIITERRYLSSVPSNFIGHLQSLTFNGMAYIDLC 883

Query: 348  KQQKPQIIAMGNVSFSCSQPQSMPVTFLSSRSYLALPDFSGEEEVSATFQFRTWNKAGLL 407
            K        + N  F      + PVTF +  SY+AL        +   FQF+T +  GL+
Sbjct: 884  KNGDIDYCEL-NARFGFRNIIADPVTFKTKSSYVALATLQAYTSMHLFFQFKTTSLDGLI 942

Query: 408  LFSE--------LQLISGGILLFLSDGKLKSNLYQPGKLPSDITAGVELNDGQWHSVSLS 459
            L++         ++L+ G  L ++ D    +NL +        ++   LND QWH+V +S
Sbjct: 943  LYNSGDGNDFIVVELVKG-YLHYVFDLGNGANLIKG-------SSNKPLNDNQWHNVMIS 994

Query: 460  AKKNHL-SVAVDGQMASAAPLLGPEQIYSGGTYYFGGCPDKSFGS--KCKSPLGGFQGCM 516
               ++L +V +D ++ +     G   +      Y GG   +++ S  K      GFQGC+
Sbjct: 995  RDTSNLHTVKIDTKITTQITA-GARNLDLKSDLYIGGVAKETYKSLPKLVHAKEGFQGCL 1053

Query: 517  RLISISGKVVDLISVQQGSLGNFSDLQID-SC-GISDRCLPNYCEHGGECSQSWSTFHCN 574
              + ++G++ DLIS        F + QI+  C G S  C  + C + G C Q W  F C+
Sbjct: 1054 ASVDLNGRLPDLISDAL-----FCNGQIERGCEGPSTTCQEDSCSNQGVCLQQWDGFSCD 1108

Query: 575  CTNTGYRGATCHNSIYEQSCEAYKHRGNTSGFYYIDSDGSGPL 617
            C+ T + G  C                N  G  YI S G G +
Sbjct: 1109 CSMTSFSGPLC----------------NDPGTTYIFSKGGGQI 1135



 Score =  114 bits (286), Expect = 5e-25
 Identities = 95/343 (27%), Positives = 155/343 (45%), Gaps = 39/343 (11%)

Query: 796  SFDTEASYLHFPTFHGELSADVSFFFKTTASSGVFLENLGIA-DFIRIELRSPTVVTFSF 854
            +F T++SY+   T     S  + F FKTT+  G+ L N G   DFI +EL     + + F
Sbjct: 908  TFKTKSSYVALATLQAYTSMHLFFQFKTTSLDGLILYNSGDGNDFIVVELVKG-YLHYVF 966

Query: 855  DVGNGPFEISVQSPTHFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNS 914
            D+GNG   I   S    NDNQWH+V + R+   ++L   ++  K       G   L L S
Sbjct: 967  DLGNGANLIKGSSNKPLNDNQWHNVMISRDT--SNLHTVKIDTKITTQITAGARNLDLKS 1024

Query: 915  QLFVGGTATR-----------QRGFLGCIRSLQLNGMTLDLEERAQV-TPEVQPGCRGHC 962
             L++GG A             + GF GC+ S+ LNG   DL   A     +++ GC G  
Sbjct: 1025 DLYIGGVAKETYKSLPKLVHAKEGFQGCLASVDLNGRLPDLISDALFCNGQIERGCEGPS 1084

Query: 963  SSYGK-LCRNGGKCRERPIGFFCDCTFSAYTGPFCSNEISAYFGS--GSSVIYNFQENYL 1019
            ++  +  C N G C ++  GF CDC+ ++++GP C++  + Y  S  G  + Y +  N  
Sbjct: 1085 TTCQEDSCSNQGVCLQQWDGFSCDCSMTSFSGPLCNDPGTTYIFSKGGGQITYKWPPNDR 1144

Query: 1020 LSKNSSSHAASFHGDMKLSREMIKFSFRTTRTPSLLLFV--SSFYKEYLSVIIAKNGSLQ 1077
             S  +               + +   F T +  ++L+ V  SS   +YL + I +    +
Sbjct: 1145 PSTRA---------------DRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQG---K 1186

Query: 1078 IRYKLNKYQEPDVVNFDFKNMADGQLHHIMINREEGVVFIEID 1120
            I  K N   +   +      + DG+ H +   R  G   +++D
Sbjct: 1187 IGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVD 1229



 Score = 97.4 bits (241), Expect = 8e-20
 Identities = 90/394 (22%), Positives = 165/394 (41%), Gaps = 69/394 (17%)

Query: 771  RLHSEAAYKLGPLLCQGDRSFWNSASFDTEASYLHFPTFHGELSADVSFFFKTTASSGVF 830
            ++H   A+K     C+   +  +  +F+T  S++  P ++ + +  +SF F+TT  +G+ 
Sbjct: 464  KIHGVVAFK-----CENVATL-DPITFETPESFISLPKWNAKKTGSISFDFRTTEPNGLI 517

Query: 831  LENLGI--------------ADFIRIELRSPTVVTFSFDVGNGPFEISVQSPTHFNDNQW 876
            L + G                DF  IE+    +     D+G+G  +I        ND +W
Sbjct: 518  LFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLL-LDMGSGTIKIKALLKK-VNDGEW 575

Query: 877  HHVRVERNMKEASLQVDQL-TPKTQPAPADGHVLLQLNSQLFVGG--------------- 920
            +HV  +R+ +  ++ V+ L TP T P  ++   +L L+ +L++GG               
Sbjct: 576  YHVDFQRDGRSGTISVNTLRTPYTAPGESE---ILDLDDELYLGGLPENKAGLVFPTEVW 632

Query: 921  TATRQRGFLGCIRSLQLNGMTLDLEERAQV--TPEVQPGCRGHCSS--YGKLCRNGGKCR 976
            TA    G++GCIR L ++G + D+ + A+V  T  V+P C    +       C+N G CR
Sbjct: 633  TALLNYGYVGCIRDLFIDGQSKDIRQMAEVQSTAGVKPSCSKETAKPCLSNPCKNNGMCR 692

Query: 977  ERPIGFFCDCTFSAYTGPFCSNEISAYFGSGSSVIYNFQENYLLSKNSSSHAASFHGDMK 1036
            +    + CDC+ + Y G  C  E +     GS  +                       M 
Sbjct: 693  DGWNRYVCDCSGTGYLGRSCEREATVLSYDGSMFM----------------KIQLPVVMH 736

Query: 1037 LSREMIKFSFRTTRTPSLLLFVSSFYKEYLSVIIAKNGSLQ-------IRYKLNKYQEPD 1089
               E +   FR+ R   +L+  +S        +    G ++       IR   N  + P+
Sbjct: 737  TEAEDVSLRFRSQRAYGILMATTSRDSADTLRLELDAGRVKLTVNLDCIRINCNSSKGPE 796

Query: 1090 VVNFDFKNMADGQLHHIMINREEGVVFIEIDDNR 1123
             + F   N+ D + H + + R    + + +DD +
Sbjct: 797  TL-FAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQ 829



 Score = 72.8 bits (177), Expect = 2e-12
 Identities = 78/346 (22%), Positives = 141/346 (40%), Gaps = 43/346 (12%)

Query: 800  EASYLHFPTFHGELSADVSFFFKTTASSGVFL--ENLGIADFIRIELRSPTVVTFSFDVG 857
            E  +  FP ++    +++SF  KT ++ G+ L  ++ G  DF+ + L     +  SF + 
Sbjct: 37   EGQWTRFPKWNACCESEMSFQLKTRSARGLVLYFDDEGFCDFLELILTRGGRLQLSFSIF 96

Query: 858  NGPFEISVQSPTHFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLF 917
                  ++ + T  ND  WH VR+ R  +  +L +DQ+  K     +     + + S LF
Sbjct: 97   CAE-PATLLADTPVNDGAWHSVRIRRQFRNTTLFIDQVEAKWVEVKSKRRD-MTVFSGLF 154

Query: 918  VGG--------------TATRQR-GFLGCIRSLQLNGMTLDLEERAQVTPEVQP------ 956
            VGG               + R+R  F G IR +++N   +   +  +V  + +P      
Sbjct: 155  VGGLPPELRAAALKLTLASVREREPFKGWIRDVRVNSSQVLPVDSGEVKLDDEPPNSGGG 214

Query: 957  -GCRGHCSSYGKLCRNGGKCRERPIGFFCDCTFSAYTGPFCSNEISAYFGSGSSVIYNFQ 1015
              C       G +C NGG C        CDC+ + + G  CS E +   G    + +   
Sbjct: 215  SPCEAGEEGEGGVCLNGGVCSVVDDQAVCDCSRTGFRGKDCSQEDNNVEG----LAHLMM 270

Query: 1016 ENYLLSKNSSSHAASFHGD-----------MKLSREMIKFSFRTTRTPSLLLFVSSFYKE 1064
             +   SK    + A+F G            ++ S + I  SF+T +   L+L       +
Sbjct: 271  GDQGKSKGKEEYIATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLHTGK-SAD 329

Query: 1065 YLSVIIAKNGSLQIRYKLNKYQEPDVVNFDFKNMADGQLHHIMINR 1110
            Y+++ + KNG++ +   L       +V        D   H + + R
Sbjct: 330  YVNLAL-KNGAVSLVINLGSGAFEALVEPVNGKFNDNAWHDVKVTR 374



 Score = 62.0 bits (149), Expect = 4e-09
 Identities = 91/382 (23%), Positives = 152/382 (39%), Gaps = 78/382 (20%)

Query: 816  DVSFFFKTTASSGVFLENLG--IADFIRIELRSPTV--------VTFSFDVGNGPFEISV 865
            DVS  F++  + G+ +       AD +R+EL +  V        +  + +   GP  +  
Sbjct: 741  DVSLRFRSQRAYGILMATTSRDSADTLRLELDAGRVKLTVNLDCIRINCNSSKGPETLF- 799

Query: 866  QSPTHFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFVGGTATRQ 925
             +  + NDN+WH VRV R  K   L VD     T     D H  L+ ++     G  T +
Sbjct: 800  -AGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMAGD-HTRLEFHN--IETGIITER 855

Query: 926  R-------GFLGCIRSLQLNGMTLDLEERAQVTPEVQPGCRGHCSSYGKLCRNGGKCRER 978
            R        F+G ++SL  NGM                       +Y  LC+NG      
Sbjct: 856  RYLSSVPSNFIGHLQSLTFNGM-----------------------AYIDLCKNGDI---- 888

Query: 979  PIGFFCDCTFSAYTGPFCSNEISAYFGSGSSVIYNFQENYLLSKNSSSHAASFHGDMKLS 1038
                            +C  E++A FG       N   + +  K  SS+ A        S
Sbjct: 889  ---------------DYC--ELNARFG-----FRNIIADPVTFKTKSSYVALATLQAYTS 926

Query: 1039 REMIKFSFRTTRTPSLLLFVSSFYKEYLSVIIAKNGSLQIRYKLNKYQEPDVVNFDFKNM 1098
              +  F F+TT    L+L+ S    +++ V + K G L   + L       +     K +
Sbjct: 927  MHLF-FQFKTTSLDGLILYNSGDGNDFIVVELVK-GYLHYVFDLGNGANL-IKGSSNKPL 983

Query: 1099 ADGQLHHIMINRE-EGVVFIEIDDNRRRQVHLSSGTEFSAVKS-LVLGRILEHSDVDQDT 1156
             D Q H++MI+R+   +  ++ID     Q+  ++G     +KS L +G + + +      
Sbjct: 984  NDNQWHNVMISRDTSNLHTVKIDTKITTQI--TAGARNLDLKSDLYIGGVAKETYKSLPK 1041

Query: 1157 ALAGAQGFTGCLSAVQLSHVAP 1178
             +   +GF GCL++V L+   P
Sbjct: 1042 LVHAKEGFQGCLASVDLNGRLP 1063



 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 41/155 (26%), Positives = 76/155 (49%), Gaps = 21/155 (13%)

Query: 814 SADVSFFFKTTASSGVFLENLGIADFIRIELRSPTVVTFSFDVGNGPFEISVQSPT-HFN 872
           S +++  FKT   +G+ L     AD++ + L++  V +   ++G+G FE  V+     FN
Sbjct: 305 SDEITLSFKTLQRNGLMLHTGKSADYVNLALKNGAV-SLVINLGSGAFEALVEPVNGKFN 363

Query: 873 DNQWHHVRVERNMKEAS--------LQVDQLTPKTQPAPADGHVLLQLNSQLFVGGTATR 924
           DN WH V+V RN+++ S        + VD +   T     D + +L  +   +VGG+ + 
Sbjct: 364 DNAWHDVKVTRNLRQHSGIGHAMVTISVDGILTTTGYTQED-YTMLGSDDFFYVGGSPST 422

Query: 925 --------QRGFLGCIRSL--QLNGMTLDLEERAQ 949
                      F+GC++ +  + N + L+L   A+
Sbjct: 423 ADLPGSPVSNNFMGCLKEVVYKNNDVRLELSRLAK 457



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 41/169 (24%), Positives = 73/169 (43%), Gaps = 18/169 (10%)

Query: 206  DIISLKFKTMQSDGILLHREGPNG--DHITLQLRRARLFLLINSGEAKLPSTSTLVNLTL 263
            D +++ F T+Q + +L+  +  +G  D++ L + + ++ +  N G      T  +     
Sbjct: 1150 DRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQGKIGVKFNVG------TDDIAIEES 1203

Query: 264  GSLLDDQHWHSVLIQRLGKQVNFTVDEHR--HHFHARGEFNLMNLDYEISFGGIPAPGKS 321
             ++++D  +H V   R G      VD       + A  +  + N    I  GG     K 
Sbjct: 1204 NAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGRQLTIFNSQATIIIGG-----KE 1258

Query: 322  VSFPHRNFHGCLENLYYNGVDIIDLAKQQKPQIIAMGNVSFSCSQPQSM 370
               P   F G L  LYYNG+ ++++A +    I  +GNV      P SM
Sbjct: 1259 QGQP---FQGQLSGLYYNGLKVLNMAAENDANIAIVGNVRLVGEVPSSM 1304



 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 50/210 (23%), Positives = 91/210 (43%), Gaps = 20/210 (9%)

Query: 391 EVSATFQFRTWNKAGLLLFSELQLISGGILLFLS-DGKLKSNLYQPGKLPSDITAGVELN 449
           E   +FQ +T +  GL+L+ + +     + L L+  G+L+ +       P+ + A   +N
Sbjct: 51  ESEMSFQLKTRSARGLVLYFDDEGFCDFLELILTRGGRLQLSFSIFCAEPATLLADTPVN 110

Query: 450 DGQWHSVSLSAKKNHLSVAVDGQMASAAPLLGPEQ---IYSGGTYYFGGCPDKSFGSKCK 506
           DG WHSV +  +  + ++ +D   A    +    +   ++SG   + GG P +   +  K
Sbjct: 111 DGAWHSVRIRRQFRNTTLFIDQVEAKWVEVKSKRRDMTVFSG--LFVGGLPPELRAAALK 168

Query: 507 SPLGG------FQGCMRLISISGKVVDLISVQQGSLGNFSDLQIDS-----CGISDRCLP 555
             L        F+G +R + ++   V  + V  G +    D   +S     C   +    
Sbjct: 169 LTLASVREREPFKGWIRDVRVNSSQV--LPVDSGEV-KLDDEPPNSGGGSPCEAGEEGEG 225

Query: 556 NYCEHGGECSQSWSTFHCNCTNTGYRGATC 585
             C +GG CS       C+C+ TG+RG  C
Sbjct: 226 GVCLNGGVCSVVDDQAVCDCSRTGFRGKDC 255


>gi|208609951 neurexin 1 isoform alpha2 precursor [Homo sapiens]
          Length = 1547

 Score =  132 bits (332), Expect = 2e-30
 Identities = 114/461 (24%), Positives = 196/461 (42%), Gaps = 82/461 (17%)

Query: 183 VVDLDGKSSLLYRFDQKSLSPIKDIISLKFKTMQSDGILLHREGPNGDHITLQLRRARLF 242
           +    G     Y   Q  +    D I+L FKT+Q +G++LH  G + D++ L L+   + 
Sbjct: 316 IATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLHT-GKSADYVNLALKNGAVS 374

Query: 243 LLINSGEAKLPSTSTLVNLTLGSLLDDQHWHSV---------------LIQRLGKQVNFT 287
           L+IN G     +    VN       +D  WH V               ++ +L   V  +
Sbjct: 375 LVINLGSGAFEALVEPVN----GKFNDNAWHDVKVTRNLRQHSGIGHAMVNKLHCSVTIS 430

Query: 288 VDEHRHHF-HARGEFNLMNLDYEISFGGIPA----PGKSVSFPHRNFHGCLENLYYNGVD 342
           VD       + + ++ ++  D     GG P+    PG  VS    NF GCL+ + Y   D
Sbjct: 431 VDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVS---NNFMGCLKEVVYKNND 487

Query: 343 I----IDLAKQQKPQIIAMGNVSFSCSQPQSM-PVTFLSSRSYLALPDFSGEEEVSATFQ 397
           +      LAKQ  P++   G V+F C    ++ P+TF +  S+++LP ++ ++  S +F 
Sbjct: 488 VRLELSRLAKQGDPKMKIHGVVAFKCENVATLDPITFETPESFISLPKWNAKKTGSISFD 547

Query: 398 FRTWNKAGLLLFSE---------------------LQLISGGILLFLSDG----KLKSNL 432
           FRT    GL+LFS                      ++++ G + L L  G    K+K+ L
Sbjct: 548 FRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALL 607

Query: 433 YQPGKLPSDITAGVELNDGQWHSVSLSAKKNHLSVAVDGQMASAAPLLGPEQIYSGGTYY 492
            +             +NDG+W+ V         +++V+            E +      Y
Sbjct: 608 KK-------------VNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDLDDELY 654

Query: 493 FGGCPDKSFGSKCKSPLG------GFQGCMRLISISGKVVDLISVQQGSLGNFSDLQIDS 546
            GG P+   G    + +       G+ GC+R + I G+  D+   Q   + + + ++  S
Sbjct: 655 LGGLPENKAGLVFPTEVWTALLNYGYVGCIRDLFIDGQSKDIR--QMAEVQSTAGVK-PS 711

Query: 547 CG--ISDRCLPNYCEHGGECSQSWSTFHCNCTNTGYRGATC 585
           C    +  CL N C++ G C   W+ + C+C+ TGY G +C
Sbjct: 712 CSKETAKPCLSNPCKNNGMCRDGWNRYVCDCSGTGYLGRSC 752



 Score =  131 bits (330), Expect = 4e-30
 Identities = 125/463 (26%), Positives = 206/463 (44%), Gaps = 61/463 (13%)

Query: 177  CAYRSEVVDLDGKSSLLYRFDQKSLSPIKDIISLKFKTMQSDGILLHREG-PNGDHITLQ 235
            C   + V+  DG   +  +      +  +D+ SL+F++ ++ GIL+      + D + L+
Sbjct: 752  CEREATVLSYDGSMFMKIQLPVVMHTEAEDV-SLRFRSQRAYGILMATTSRDSADTLRLE 810

Query: 236  LRRARLFLLINSGEAKLPSTSTLVNLTL--GSLLDDQHWHSVLIQRLGKQVNFTVDEHRH 293
            L   R+ L +N    ++   S+    TL  G  L+D  WH+V + R GK +  TVD+ + 
Sbjct: 811  LDAGRVKLTVNLDCIRINCNSSKGPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQA 870

Query: 294  HF------HARGEFNLMNLDYEISFGGIPAPGKSVSFPHRNFHGCLENLYYNGVDIIDLA 347
                    H R EF+ +         GI    + +S    NF G L++L +NG+  IDL 
Sbjct: 871  MTGQMAGDHTRLEFHNIET-------GIITERRYLSSVPSNFIGHLQSLTFNGMAYIDLC 923

Query: 348  KQQKPQIIAMGNVSFSCSQPQSMPVTFLSSRSYLALPDFSGEEEVSATFQFRTWNKAGLL 407
            K        + N  F      + PVTF +  SY+AL        +   FQF+T +  GL+
Sbjct: 924  KNGDIDYCEL-NARFGFRNIIADPVTFKTKSSYVALATLQAYTSMHLFFQFKTTSLDGLI 982

Query: 408  LFSE--------LQLISGGILLFLSDGKLKSNLYQPGKLPSDITAGVELNDGQWHSVSLS 459
            L++         ++L+ G  L ++ D    +NL +        ++   LND QWH+V +S
Sbjct: 983  LYNSGDGNDFIVVELVKG-YLHYVFDLGNGANLIKG-------SSNKPLNDNQWHNVMIS 1034

Query: 460  AKKNHL-SVAVDGQMASAAPLLGPEQIYSGGTYYFGGCPDKSFGS--KCKSPLGGFQGCM 516
               ++L +V +D ++ +     G   +      Y GG   +++ S  K      GFQGC+
Sbjct: 1035 RDTSNLHTVKIDTKITTQITA-GARNLDLKSDLYIGGVAKETYKSLPKLVHAKEGFQGCL 1093

Query: 517  RLISISGKVVDLISVQQGSLGNFSDLQID-SC-GISDRCLPNYCEHGGECSQSWSTFHCN 574
              + ++G++ DLIS        F + QI+  C G S  C  + C + G C Q W  F C+
Sbjct: 1094 ASVDLNGRLPDLISDAL-----FCNGQIERGCEGPSTTCQEDSCSNQGVCLQQWDGFSCD 1148

Query: 575  CTNTGYRGATCHNSIYEQSCEAYKHRGNTSGFYYIDSDGSGPL 617
            C+ T + G  C                N  G  YI S G G +
Sbjct: 1149 CSMTSFSGPLC----------------NDPGTTYIFSKGGGQI 1175



 Score =  114 bits (286), Expect = 5e-25
 Identities = 95/343 (27%), Positives = 155/343 (45%), Gaps = 39/343 (11%)

Query: 796  SFDTEASYLHFPTFHGELSADVSFFFKTTASSGVFLENLGIA-DFIRIELRSPTVVTFSF 854
            +F T++SY+   T     S  + F FKTT+  G+ L N G   DFI +EL     + + F
Sbjct: 948  TFKTKSSYVALATLQAYTSMHLFFQFKTTSLDGLILYNSGDGNDFIVVELVKG-YLHYVF 1006

Query: 855  DVGNGPFEISVQSPTHFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNS 914
            D+GNG   I   S    NDNQWH+V + R+   ++L   ++  K       G   L L S
Sbjct: 1007 DLGNGANLIKGSSNKPLNDNQWHNVMISRDT--SNLHTVKIDTKITTQITAGARNLDLKS 1064

Query: 915  QLFVGGTATR-----------QRGFLGCIRSLQLNGMTLDLEERAQV-TPEVQPGCRGHC 962
             L++GG A             + GF GC+ S+ LNG   DL   A     +++ GC G  
Sbjct: 1065 DLYIGGVAKETYKSLPKLVHAKEGFQGCLASVDLNGRLPDLISDALFCNGQIERGCEGPS 1124

Query: 963  SSYGK-LCRNGGKCRERPIGFFCDCTFSAYTGPFCSNEISAYFGS--GSSVIYNFQENYL 1019
            ++  +  C N G C ++  GF CDC+ ++++GP C++  + Y  S  G  + Y +  N  
Sbjct: 1125 TTCQEDSCSNQGVCLQQWDGFSCDCSMTSFSGPLCNDPGTTYIFSKGGGQITYKWPPNDR 1184

Query: 1020 LSKNSSSHAASFHGDMKLSREMIKFSFRTTRTPSLLLFV--SSFYKEYLSVIIAKNGSLQ 1077
             S  +               + +   F T +  ++L+ V  SS   +YL + I +    +
Sbjct: 1185 PSTRA---------------DRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQG---K 1226

Query: 1078 IRYKLNKYQEPDVVNFDFKNMADGQLHHIMINREEGVVFIEID 1120
            I  K N   +   +      + DG+ H +   R  G   +++D
Sbjct: 1227 IGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVD 1269



 Score = 97.4 bits (241), Expect = 8e-20
 Identities = 90/394 (22%), Positives = 165/394 (41%), Gaps = 69/394 (17%)

Query: 771  RLHSEAAYKLGPLLCQGDRSFWNSASFDTEASYLHFPTFHGELSADVSFFFKTTASSGVF 830
            ++H   A+K     C+   +  +  +F+T  S++  P ++ + +  +SF F+TT  +G+ 
Sbjct: 504  KIHGVVAFK-----CENVATL-DPITFETPESFISLPKWNAKKTGSISFDFRTTEPNGLI 557

Query: 831  LENLGI--------------ADFIRIELRSPTVVTFSFDVGNGPFEISVQSPTHFNDNQW 876
            L + G                DF  IE+    +     D+G+G  +I        ND +W
Sbjct: 558  LFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLL-LDMGSGTIKIKALLKK-VNDGEW 615

Query: 877  HHVRVERNMKEASLQVDQL-TPKTQPAPADGHVLLQLNSQLFVGG--------------- 920
            +HV  +R+ +  ++ V+ L TP T P  ++   +L L+ +L++GG               
Sbjct: 616  YHVDFQRDGRSGTISVNTLRTPYTAPGESE---ILDLDDELYLGGLPENKAGLVFPTEVW 672

Query: 921  TATRQRGFLGCIRSLQLNGMTLDLEERAQV--TPEVQPGCRGHCSS--YGKLCRNGGKCR 976
            TA    G++GCIR L ++G + D+ + A+V  T  V+P C    +       C+N G CR
Sbjct: 673  TALLNYGYVGCIRDLFIDGQSKDIRQMAEVQSTAGVKPSCSKETAKPCLSNPCKNNGMCR 732

Query: 977  ERPIGFFCDCTFSAYTGPFCSNEISAYFGSGSSVIYNFQENYLLSKNSSSHAASFHGDMK 1036
            +    + CDC+ + Y G  C  E +     GS  +                       M 
Sbjct: 733  DGWNRYVCDCSGTGYLGRSCEREATVLSYDGSMFM----------------KIQLPVVMH 776

Query: 1037 LSREMIKFSFRTTRTPSLLLFVSSFYKEYLSVIIAKNGSLQ-------IRYKLNKYQEPD 1089
               E +   FR+ R   +L+  +S        +    G ++       IR   N  + P+
Sbjct: 777  TEAEDVSLRFRSQRAYGILMATTSRDSADTLRLELDAGRVKLTVNLDCIRINCNSSKGPE 836

Query: 1090 VVNFDFKNMADGQLHHIMINREEGVVFIEIDDNR 1123
             + F   N+ D + H + + R    + + +DD +
Sbjct: 837  TL-FAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQ 869



 Score = 68.6 bits (166), Expect = 4e-11
 Identities = 56/225 (24%), Positives = 93/225 (41%), Gaps = 26/225 (11%)

Query: 800  EASYLHFPTFHGELSADVSFFFKTTASSGVFL--ENLGIADFIRIELRSPTVVTFSFDVG 857
            E  +  FP ++    +++SF  KT ++ G+ L  ++ G  DF+ + L     +  SF + 
Sbjct: 37   EGQWTRFPKWNACCESEMSFQLKTRSARGLVLYFDDEGFCDFLELILTRGGRLQLSFSIF 96

Query: 858  NGPFEISVQSPTHFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLF 917
                  ++ + T  ND  WH VR+ R  +  +L +DQ+  K     +    +    S LF
Sbjct: 97   CAE-PATLLADTPVNDGAWHSVRIRRQFRNTTLFIDQVEAKWVEVKSKRRDMTVF-SGLF 154

Query: 918  VGGTATRQRG---------------FLGCIRSLQLNGMTLDLEERAQVTPEVQPG----- 957
            VGG     R                F G IR +++N   +   +  +V  + +P      
Sbjct: 155  VGGLPPELRAAALKLTLASVREREPFKGWIRDVRVNSSQVLPVDSGEVKLDDEPPNSGGG 214

Query: 958  --CRGHCSSYGKLCRNGGKCRERPIGFFCDCTFSAYTGPFCSNEI 1000
              C       G +C NGG C        CDC+ + + G  CS EI
Sbjct: 215  SPCEAGEEGEGGVCLNGGVCSVVDDQAVCDCSRTGFRGKDCSQEI 259



 Score = 62.0 bits (149), Expect = 4e-09
 Identities = 91/382 (23%), Positives = 152/382 (39%), Gaps = 78/382 (20%)

Query: 816  DVSFFFKTTASSGVFLENLG--IADFIRIELRSPTV--------VTFSFDVGNGPFEISV 865
            DVS  F++  + G+ +       AD +R+EL +  V        +  + +   GP  +  
Sbjct: 781  DVSLRFRSQRAYGILMATTSRDSADTLRLELDAGRVKLTVNLDCIRINCNSSKGPETLF- 839

Query: 866  QSPTHFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFVGGTATRQ 925
             +  + NDN+WH VRV R  K   L VD     T     D H  L+ ++     G  T +
Sbjct: 840  -AGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMAGD-HTRLEFHN--IETGIITER 895

Query: 926  R-------GFLGCIRSLQLNGMTLDLEERAQVTPEVQPGCRGHCSSYGKLCRNGGKCRER 978
            R        F+G ++SL  NGM                       +Y  LC+NG      
Sbjct: 896  RYLSSVPSNFIGHLQSLTFNGM-----------------------AYIDLCKNGDI---- 928

Query: 979  PIGFFCDCTFSAYTGPFCSNEISAYFGSGSSVIYNFQENYLLSKNSSSHAASFHGDMKLS 1038
                            +C  E++A FG       N   + +  K  SS+ A        S
Sbjct: 929  ---------------DYC--ELNARFG-----FRNIIADPVTFKTKSSYVALATLQAYTS 966

Query: 1039 REMIKFSFRTTRTPSLLLFVSSFYKEYLSVIIAKNGSLQIRYKLNKYQEPDVVNFDFKNM 1098
              +  F F+TT    L+L+ S    +++ V + K G L   + L       +     K +
Sbjct: 967  MHLF-FQFKTTSLDGLILYNSGDGNDFIVVELVK-GYLHYVFDLGNGANL-IKGSSNKPL 1023

Query: 1099 ADGQLHHIMINRE-EGVVFIEIDDNRRRQVHLSSGTEFSAVKS-LVLGRILEHSDVDQDT 1156
             D Q H++MI+R+   +  ++ID     Q+  ++G     +KS L +G + + +      
Sbjct: 1024 NDNQWHNVMISRDTSNLHTVKIDTKITTQI--TAGARNLDLKSDLYIGGVAKETYKSLPK 1081

Query: 1157 ALAGAQGFTGCLSAVQLSHVAP 1178
             +   +GF GCL++V L+   P
Sbjct: 1082 LVHAKEGFQGCLASVDLNGRLP 1103



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 51/214 (23%), Positives = 92/214 (42%), Gaps = 20/214 (9%)

Query: 391 EVSATFQFRTWNKAGLLLFSELQLISGGILLFLS-DGKLKSNLYQPGKLPSDITAGVELN 449
           E   +FQ +T +  GL+L+ + +     + L L+  G+L+ +       P+ + A   +N
Sbjct: 51  ESEMSFQLKTRSARGLVLYFDDEGFCDFLELILTRGGRLQLSFSIFCAEPATLLADTPVN 110

Query: 450 DGQWHSVSLSAKKNHLSVAVDGQMASAAPLLGPEQ---IYSGGTYYFGGCPDKSFGSKCK 506
           DG WHSV +  +  + ++ +D   A    +    +   ++SG   + GG P +   +  K
Sbjct: 111 DGAWHSVRIRRQFRNTTLFIDQVEAKWVEVKSKRRDMTVFSG--LFVGGLPPELRAAALK 168

Query: 507 SPLGG------FQGCMRLISISGKVVDLISVQQGSLGNFSDLQIDS-----CGISDRCLP 555
             L        F+G +R + ++   V  + V  G +    D   +S     C   +    
Sbjct: 169 LTLASVREREPFKGWIRDVRVNSSQV--LPVDSGEV-KLDDEPPNSGGGSPCEAGEEGEG 225

Query: 556 NYCEHGGECSQSWSTFHCNCTNTGYRGATCHNSI 589
             C +GG CS       C+C+ TG+RG  C   I
Sbjct: 226 GVCLNGGVCSVVDDQAVCDCSRTGFRGKDCSQEI 259



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 41/162 (25%), Positives = 76/162 (46%), Gaps = 28/162 (17%)

Query: 814 SADVSFFFKTTASSGVFLENLGIADFIRIELRSPTVVTFSFDVGNGPFEISVQSPT-HFN 872
           S +++  FKT   +G+ L     AD++ + L++  V +   ++G+G FE  V+     FN
Sbjct: 338 SDEITLSFKTLQRNGLMLHTGKSADYVNLALKNGAV-SLVINLGSGAFEALVEPVNGKFN 396

Query: 873 DNQWHHVRVERNMKEAS---------------LQVDQLTPKTQPAPADGHVLLQLNSQLF 917
           DN WH V+V RN+++ S               + VD +   T     D + +L  +   +
Sbjct: 397 DNAWHDVKVTRNLRQHSGIGHAMVNKLHCSVTISVDGILTTTGYTQED-YTMLGSDDFFY 455

Query: 918 VGGTATR--------QRGFLGCIRSL--QLNGMTLDLEERAQ 949
           VGG+ +            F+GC++ +  + N + L+L   A+
Sbjct: 456 VGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDVRLELSRLAK 497



 Score = 40.8 bits (94), Expect = 0.009
 Identities = 41/194 (21%), Positives = 75/194 (38%), Gaps = 38/194 (19%)

Query: 206  DIISLKFKTMQSDGILLHREGPNG--DHITLQLRRARLFLLINSGEAKLPSTSTLVNLTL 263
            D +++ F T+Q + +L+  +  +G  D++ L + + ++ +  N G      T  +     
Sbjct: 1190 DRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQGKIGVKFNVG------TDDIAIEES 1243

Query: 264  GSLLDDQHWHSVLIQRLGKQVNFTVDEHR--------HHFHARGEFNLMNLDYEI----- 310
             ++++D  +H V   R G      VD           ++ + R       + Y +     
Sbjct: 1244 NAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGNNDNERLAIARQRIPYRLGRVVD 1303

Query: 311  --------------SFGGIPAPGKSVSFPHRNFHGCLENLYYNGVDIIDLAKQQKPQIIA 356
                          S   I   GK    P   F G L  LYYNG+ ++++A +    I  
Sbjct: 1304 EWLLDKGRQLTIFNSQATIIIGGKEQGQP---FQGQLSGLYYNGLKVLNMAAENDANIAI 1360

Query: 357  MGNVSFSCSQPQSM 370
            +GNV      P SM
Sbjct: 1361 VGNVRLVGEVPSSM 1374


>gi|21070969 neurexin 3 isoform 1 precursor [Homo sapiens]
          Length = 1061

 Score =  125 bits (315), Expect = 2e-28
 Identities = 108/429 (25%), Positives = 188/429 (43%), Gaps = 38/429 (8%)

Query: 177 CAYRSEVVDLDGKSSLLYRFDQKSLSPIKDIISLKFKTMQSDGILLHREG-PNGDHITLQ 235
           C   + ++  DG   +         +  +D+ S +F + ++ G+L+      + D + L+
Sbjct: 306 CEREASILSYDGSMYMKIIMPMVMHTEAEDV-SFRFMSQRAYGLLVATTSRDSADTLRLE 364

Query: 236 LRRARLFLLINSGEAKLPSTSTLVNLTL--GSLLDDQHWHSVLIQRLGKQVNFTVDEHRH 293
           L   R+ L++N    ++   S+    TL  G  L+D  WH+V + R GK +  TVD+   
Sbjct: 365 LDGGRVKLMVNLDCIRINCNSSKGPETLYAGQKLNDNEWHTVRVVRRGKSLKLTVDDDVA 424

Query: 294 HFHARGEFNLMNLDYEISFGGIPAPGKSVSFPHRNFHGCLENLYYNGVDIIDLAKQQKPQ 353
                G+     L++     GI    + +S    +F G L++L +NG+  IDL K     
Sbjct: 425 EGTMVGDHT--RLEFHNIETGIMTEKRYISVVPSSFIGHLQSLMFNGLLYIDLCKNGDID 482

Query: 354 IIAMGNVSFSCSQPQSMPVTFLSSRSYLALPDFSGEEEVSATFQFRTWNKAGLLLFSE-- 411
              +    F      + PVTF +  SYL+L        +   FQF+T +  G +LF+   
Sbjct: 483 YCEL-KARFGLRNIIADPVTFKTKSSYLSLATLQAYTSMHLFFQFKTTSPDGFILFNSGD 541

Query: 412 ------LQLISGGILLFLSDGK----LKSNLYQPGKLPSDITAGVELNDGQWHSVSLSA- 460
                 ++L+ G I      G     +K N  +P            LND QWH+V ++  
Sbjct: 542 GNDFIAVELVKGYIHYVFDLGNGPNVIKGNSDRP------------LNDNQWHNVVITRD 589

Query: 461 KKNHLSVAVDGQMASAAPLLGPEQIYSGGTYYFGGCPDKSFGS--KCKSPLGGFQGCMRL 518
             N  S+ VD ++ +   + G + +   G  Y  G     + +  K  +   GFQGC+  
Sbjct: 590 NSNTHSLKVDTKVVTQV-INGAKNLDLKGDLYMAGLAQGMYSNLPKLVASRDGFQGCLAS 648

Query: 519 ISISGKVVDLISVQQGSLGNFSDLQIDSCGISDRCLPNYCEHGGECSQSWSTFHCNCTNT 578
           + ++G++ DLI+    +L     ++    G S  C  + C + G C Q W  F C+C+ T
Sbjct: 649 VDLNGRLPDLIN---DALHRSGQIERGCEGPSTTCQEDSCANQGVCMQQWEGFTCDCSMT 705

Query: 579 GYRGATCHN 587
            Y G  C++
Sbjct: 706 SYSGNQCND 714



 Score =  119 bits (299), Expect = 1e-26
 Identities = 142/577 (24%), Positives = 233/577 (40%), Gaps = 92/577 (15%)

Query: 796  SFDTEASYLHFPTFHGELSADVSFFFKTTASSGVFLENLGIA-DFIRIELRSPTVVTFSF 854
            +F T++SYL   T     S  + F FKTT+  G  L N G   DFI +EL     + + F
Sbjct: 501  TFKTKSSYLSLATLQAYTSMHLFFQFKTTSPDGFILFNSGDGNDFIAVELVKG-YIHYVF 559

Query: 855  DVGNGPFEISVQSPTHFNDNQWHHVRVER-NMKEASLQVDQLTPKTQPAPADGHVLLQLN 913
            D+GNGP  I   S    NDNQWH+V + R N    SL+VD    K      +G   L L 
Sbjct: 560  DLGNGPNVIKGNSDRPLNDNQWHNVVITRDNSNTHSLKVD---TKVVTQVINGAKNLDLK 616

Query: 914  SQLFVGGTA-----------TRQRGFLGCIRSLQLNGMTLDL-EERAQVTPEVQPGCRGH 961
              L++ G A             + GF GC+ S+ LNG   DL  +    + +++ GC G 
Sbjct: 617  GDLYMAGLAQGMYSNLPKLVASRDGFQGCLASVDLNGRLPDLINDALHRSGQIERGCEGP 676

Query: 962  CSSYGK-LCRNGGKCRERPIGFFCDCTFSAYTGPFCSNEISAY-FG-SGSSVIYNFQENY 1018
             ++  +  C N G C ++  GF CDC+ ++Y+G  C++  + Y FG SG  ++Y +  N 
Sbjct: 677  STTCQEDSCANQGVCMQQWEGFTCDCSMTSYSGNQCNDPGATYIFGKSGGLILYTWPAND 736

Query: 1019 LLSKNSSSHAASFHGDMKLSREMIKFSFRTTRTPSLLLFVSSFYKEYLSVIIAKNGSLQI 1078
              S  S   A  F   +K          R    P L  F+    ++    ++   G++ I
Sbjct: 737  RPSTRSDRLAVGFSTTVKDG-----ILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDI 791

Query: 1079 RYKLNKYQEPDVVNFDFKNMADGQLHHIMINREEGVVFIEIDD----------------N 1122
              K    +E   VN       DG+ H +   R  G   +++D+                N
Sbjct: 792  SIK----EERTPVN-------DGKYHVVRFTRNGGNATLQVDNWPVNEHYPTGRQLTIFN 840

Query: 1123 RRRQVHLS------------SGTEFSAVKSLVLGRILEHS---DVDQDTALAGAQGFTGC 1167
             + Q+ +             SG  +  +K  VL    E++    ++    L G       
Sbjct: 841  TQAQIAIGGKDKGRLFQGQLSGLYYDGLK--VLNMAAENNPNIKINGSVRLVGE--VPSI 896

Query: 1168 LSAVQLSHVAP-LKAALHPSHPDPVTVTGHVTESSCMAQPGTD--ATSRERTHSFAD--- 1221
            L   Q + + P +   +  +     T T     S+   QP +D   +S E +    D   
Sbjct: 897  LGTTQTTSMPPEMSTTVMETTTTMATTTTRKNRSTASIQPTSDDLVSSAECSSDDEDFVE 956

Query: 1222 -HSGTIDDREP-------LANAIKSDSAVIGGLIAVVIFILLCITAIAVRIYQQKR---- 1269
                T +  EP        +  I+  S+  G ++ +V    LCI  +   +Y+ +     
Sbjct: 957  CEPSTANPTEPGIRRVPGASEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEG 1016

Query: 1270 LYKRSEAKR--SENVDSAEAVLKSELNIQNAVNENQK 1304
             Y+  E +   S +  S   ++K +     + ++ QK
Sbjct: 1017 SYQVDETRNYISNSAQSNGTLMKEKQQSSKSGHKKQK 1053



 Score = 93.6 bits (231), Expect = 1e-18
 Identities = 78/310 (25%), Positives = 131/310 (42%), Gaps = 51/310 (16%)

Query: 313 GGIPA----PGKSVSFPHRNFHGCLENLYYNGVDI----IDLAKQQKPQIIAMGNVSFSC 364
           GG P+    PG  VS    NF GCL+ + Y   DI      LA+    ++   G V F C
Sbjct: 11  GGSPSTADLPGSPVS---NNFMGCLKEVVYKNNDIRLELSRLARIADTKMKIYGEVVFKC 67

Query: 365 SQPQSM-PVTFLSSRSYLALPDFSGEEEVSATFQFRTWNKAGLLLFSE------------ 411
               ++ P+ F +  +Y++LP ++ +   S +F FRT    GL+LF+             
Sbjct: 68  ENVATLDPINFETPEAYISLPKWNTKRMGSISFDFRTTEPNGLILFTHGKPQERKDARSQ 127

Query: 412 ---------LQLISGGILLFLSDGKLKSNLYQPGKLPSDITAGVELNDGQWHSVSLSAKK 462
                    ++L+ G + L L  G     +    K         + NDG+W+ V +    
Sbjct: 128 KNTKVDFFAVELLDGNLYLLLDMGSGTIKVKATQK---------KANDGEWYHVDIQRDG 178

Query: 463 NHLSVAVDGQMASAAPLLGPEQIYSGGTYYFGGCPDKSFGSKCKSPLG------GFQGCM 516
              +++V+ +          E +   G  Y GG P+   G    + L       G+ GC+
Sbjct: 179 RSGTISVNSRRTPFTASGESEILDLEGDMYLGGLPENRAGLILPTELWTAMLNYGYVGCI 238

Query: 517 RLISISGKVVDLISVQQGSLGNFSDLQIDSCGISDRCLPNY-CEHGGECSQSWSTFHCNC 575
           R + I G+  ++   Q   + N + ++     +S +   +Y C++   C   W+ F C+C
Sbjct: 239 RDLFIDGRSKNIR--QLAEMQNAAGVKSSCSRMSAKQCDSYPCKNNAVCKDGWNRFICDC 296

Query: 576 TNTGYRGATC 585
           T TGY G TC
Sbjct: 297 TGTGYWGRTC 306



 Score = 85.1 bits (209), Expect = 4e-16
 Identities = 63/249 (25%), Positives = 112/249 (44%), Gaps = 43/249 (17%)

Query: 796  SFDTEASYLHFPTFHGELSADVSFFFKTTASSGVFLENLGI--------------ADFIR 841
            +F+T  +Y+  P ++ +    +SF F+TT  +G+ L   G                DF  
Sbjct: 77   NFETPEAYISLPKWNTKRMGSISFDFRTTEPNGLILFTHGKPQERKDARSQKNTKVDFFA 136

Query: 842  IELRSPTVVTFSFDVGNGPFEISVQSPTHFNDNQWHHVRVERNMKEASLQVD-QLTPKTQ 900
            +EL    +     D+G+G  ++   +    ND +W+HV ++R+ +  ++ V+ + TP T 
Sbjct: 137  VELLDGNLYLL-LDMGSGTIKVKA-TQKKANDGEWYHVDIQRDGRSGTISVNSRRTPFTA 194

Query: 901  PAPADGHVLLQLNSQLFVGG---------------TATRQRGFLGCIRSLQLNGMTLDLE 945
               ++   +L L   +++GG               TA    G++GCIR L ++G + ++ 
Sbjct: 195  SGESE---ILDLEGDMYLGGLPENRAGLILPTELWTAMLNYGYVGCIRDLFIDGRSKNIR 251

Query: 946  ERAQV--TPEVQPGCRG----HCSSYGKLCRNGGKCRERPIGFFCDCTFSAYTGPFCSNE 999
            + A++     V+  C       C SY   C+N   C++    F CDCT + Y G  C  E
Sbjct: 252  QLAEMQNAAGVKSSCSRMSAKQCDSYP--CKNNAVCKDGWNRFICDCTGTGYWGRTCERE 309

Query: 1000 ISAYFGSGS 1008
             S     GS
Sbjct: 310  ASILSYDGS 318



 Score = 66.6 bits (161), Expect = 1e-10
 Identities = 77/336 (22%), Positives = 132/336 (39%), Gaps = 78/336 (23%)

Query: 208 ISLKFKTMQSDGILLHREGP-------------NGDHITLQLRRARLFLLIN--SGEAKL 252
           IS  F+T + +G++L   G                D   ++L    L+LL++  SG  K+
Sbjct: 98  ISFDFRTTEPNGLILFTHGKPQERKDARSQKNTKVDFFAVELLDGNLYLLLDMGSGTIKV 157

Query: 253 PSTSTLVNLTLGSLLDDQHWHSVLIQRLGKQVNFTVDEHRHHFHARGEFNLMNLDYEISF 312
            +T    N        D  W+ V IQR G+    +V+  R  F A GE  +++L+ ++  
Sbjct: 158 KATQKKAN--------DGEWYHVDIQRDGRSGTISVNSRRTPFTASGESEILDLEGDMYL 209

Query: 313 GGIPAPGKSVSFP--------HRNFHGCLENLYYNG--VDIIDLAKQQKPQIIAMGNVSF 362
           GG+P     +  P        +  + GC+ +L+ +G   +I  LA+ Q    +       
Sbjct: 210 GGLPENRAGLILPTELWTAMLNYGYVGCIRDLFIDGRSKNIRQLAEMQNAAGVKSSCSRM 269

Query: 363 SCSQPQSMPV-----------TFL-----------------SSRSY-------LALPDFS 387
           S  Q  S P             F+                 S  SY       + +P   
Sbjct: 270 SAKQCDSYPCKNNAVCKDGWNRFICDCTGTGYWGRTCEREASILSYDGSMYMKIIMPMVM 329

Query: 388 GEEEVSATFQFRTWNKAGLLLFS---------ELQLISGGILLFLSDGKLKSNLYQPGKL 438
             E    +F+F +    GLL+ +          L+L  G + L ++   ++ N     K 
Sbjct: 330 HTEAEDVSFRFMSQRAYGLLVATTSRDSADTLRLELDGGRVKLMVNLDCIRINC-NSSKG 388

Query: 439 PSDITAGVELNDGQWHSVSLSAKKNHLSVAVDGQMA 474
           P  + AG +LND +WH+V +  +   L + VD  +A
Sbjct: 389 PETLYAGQKLNDNEWHTVRVVRRGKSLKLTVDDDVA 424



 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 90/393 (22%), Positives = 151/393 (38%), Gaps = 83/393 (21%)

Query: 816  DVSFFFKTTASSGVFLENLG--IADFIRIELRSPTV--------VTFSFDVGNGPFEISV 865
            DVSF F +  + G+ +       AD +R+EL    V        +  + +   GP   ++
Sbjct: 335  DVSFRFMSQRAYGLLVATTSRDSADTLRLELDGGRVKLMVNLDCIRINCNSSKGPE--TL 392

Query: 866  QSPTHFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFVGGTATRQ 925
             +    NDN+WH VRV R  K   L VD      +      H  L+ ++     G  T +
Sbjct: 393  YAGQKLNDNEWHTVRVVRRGKSLKLTVDD--DVAEGTMVGDHTRLEFHN--IETGIMTEK 448

Query: 926  R-------GFLGCIRSLQLNGMTLDLEERAQVTPEVQPGCRGHCSSYGKLCRNGGKCRER 978
            R        F+G ++SL  NG+                        Y  LC+NG      
Sbjct: 449  RYISVVPSSFIGHLQSLMFNGLL-----------------------YIDLCKNGDI---- 481

Query: 979  PIGFFCDCTFSAYTGPFCSNEISAYFGSGSSVIYNFQENYLLSKNSSSHAASFHGDMKLS 1038
                            +C  E+ A FG     + N   + +  K  SS+ +        S
Sbjct: 482  ---------------DYC--ELKARFG-----LRNIIADPVTFKTKSSYLSLATLQAYTS 519

Query: 1039 REMIKFSFRTTRTPSLLLFVSSFYKEYLSVIIAKNGSLQIRYKLNKYQEPDVV--NFDFK 1096
              +  F F+TT     +LF S    ++++V + K     I Y  +    P+V+  N D +
Sbjct: 520  MHLF-FQFKTTSPDGFILFNSGDGNDFIAVELVKG---YIHYVFDLGNGPNVIKGNSD-R 574

Query: 1097 NMADGQLHHIMINREEGVVF-IEIDDNRRRQVHLSSGTEFSAVKSLVLGRILEHSDVDQD 1155
             + D Q H+++I R+      +++D     QV ++          L +  + +    +  
Sbjct: 575  PLNDNQWHNVVITRDNSNTHSLKVDTKVVTQV-INGAKNLDLKGDLYMAGLAQGMYSNLP 633

Query: 1156 TALAGAQGFTGCLSAVQLSHVAP--LKAALHPS 1186
              +A   GF GCL++V L+   P  +  ALH S
Sbjct: 634  KLVASRDGFQGCLASVDLNGRLPDLINDALHRS 666



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 43/178 (24%), Positives = 73/178 (41%), Gaps = 22/178 (12%)

Query: 206 DIISLKFKTMQSDGILLHREGPNG--DHITLQLRRARLFLLINSG--EAKLPSTSTLVNL 261
           D +++ F T   DGIL+  +   G  D + L + + ++ ++ N G  +  +    T VN 
Sbjct: 743 DRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIKEERTPVN- 801

Query: 262 TLGSLLDDQHWHSVLIQRLGKQVNFTVDEH--RHHFHARGEFNLMNLDYEISFGGIPAPG 319
                  D  +H V   R G      VD      H+    +  + N   +I+ GG     
Sbjct: 802 -------DGKYHVVRFTRNGGNATLQVDNWPVNEHYPTGRQLTIFNTQAQIAIGG----- 849

Query: 320 KSVSFPHRNFHGCLENLYYNGVDIIDLAKQQKPQIIAMGNVSFSCSQPQSMPVTFLSS 377
                  R F G L  LYY+G+ ++++A +  P I   G+V      P  +  T  +S
Sbjct: 850 ---KDKGRLFQGQLSGLYYDGLKVLNMAAENNPNIKINGSVRLVGEVPSILGTTQTTS 904


>gi|239752499 PREDICTED: similar to cell recognition molecule Caspr2,
            partial [Homo sapiens]
          Length = 140

 Score =  107 bits (268), Expect = 6e-23
 Identities = 49/74 (66%), Positives = 63/74 (85%)

Query: 1074 GSLQIRYKLNKYQEPDVVNFDFKNMADGQLHHIMINREEGVVFIEIDDNRRRQVHLSSGT 1133
            GSLQIRYKL+++Q PD   FDFKNMADGQLH + INREE VV +E++ + ++QV LSSGT
Sbjct: 2    GSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVEVNQSAKKQVILSSGT 61

Query: 1134 EFSAVKSLVLGRIL 1147
            EF+AVKSL+LG++L
Sbjct: 62   EFNAVKSLILGKVL 75


>gi|105990535 coagulation factor V precursor [Homo sapiens]
          Length = 2224

 Score = 86.3 bits (212), Expect = 2e-16
 Identities = 49/126 (38%), Positives = 67/126 (53%), Gaps = 6/126 (4%)

Query: 56   PGFARLNRRDGAGGWSPLVSNKYQWLQIDLGERMEVTAVATQG--GYGSSNWVTSYLLMF 113
            P  ARLN +     W    +N  QWL+IDL +  ++TA+ TQG     S  +V SY + +
Sbjct: 2098 PFRARLNAQGRVNAWQAKANNNKQWLEIDLLKIKKITAIITQGCKSLSSEMYVKSYTIHY 2157

Query: 114  SDSGWNWKQYRQEDSIWG--FSGNANADSVVYYRLQPSIKARFLRFIPLEWNPKGRIGMR 171
            S+ G  WK YR + S+    F GN N    V     P I +RF+R IP  WN    I +R
Sbjct: 2158 SEQGVEWKPYRLKSSMVDKIFEGNTNTKGHVKNFFNPPIISRFIRVIPKTWNQS--IALR 2215

Query: 172  IEVFGC 177
            +E+FGC
Sbjct: 2216 LELFGC 2221



 Score = 58.5 bits (140), Expect = 4e-08
 Identities = 43/158 (27%), Positives = 75/158 (47%), Gaps = 12/158 (7%)

Query: 30   DCDDP--LVSALPQASFSSSSELSSSHGPGFARLNRRDGAGGWS--PLVSN--KYQWLQI 83
            DC  P  L + +   S   +SE      P  ARLN       WS   L +      W+Q+
Sbjct: 1906 DCRMPMGLSTGIISDSQIKASEFLGYWEPRLARLNNGGSYNAWSVEKLAAEFASKPWIQV 1965

Query: 84   DLGERMEVTAVATQGG--YGSSNWVTSYLLMFSDSGWNWKQYRQEDS--IWGFSGNANAD 139
            D+ + + +T + TQG   Y  S + T + + +S +  NW+ ++   +  +  F+GN++A 
Sbjct: 1966 DMQKEVIITGIQTQGAKHYLKSCYTTEFYVAYSSNQINWQIFKGNSTRNVMYFNGNSDAS 2025

Query: 140  SVVYYRLQPSIKARFLRFIPLEWNPKGRIGMRIEVFGC 177
            ++   +  P I AR++R  P       R  +R+E+ GC
Sbjct: 2026 TIKENQFDPPIVARYIRISPT--RAYNRPTLRLELQGC 2061


>gi|54873613 agrin [Homo sapiens]
          Length = 2045

 Score = 82.0 bits (201), Expect = 3e-15
 Identities = 63/230 (27%), Positives = 99/230 (43%), Gaps = 18/230 (7%)

Query: 364  CSQPQSMPVTFLSSRSYLALPDFSGEEEVSATFQFRTWNKAGLLLFSELQLISGGILLFL 423
            C +    PV     RS+LA P       +    +FR     GLLL++        + L L
Sbjct: 1366 CEKVLGAPVPAFEGRSFLAFPTLRAYHTLRLALEFRALEPQGLLLYNGNARGKDFLALAL 1425

Query: 424  SDGKLKSNLYQPGKLPSDITAGVELNDGQWHSVSLSAKKNHLSVAVDGQMASAAPLLGPE 483
             DG+++   +  G  P+ +T+ V +  GQWH + LS      +++VDG+     P+LG  
Sbjct: 1426 LDGRVQLR-FDTGSGPAVLTSAVPVEPGQWHRLELSRHWRRGTLSVDGE----TPVLGES 1480

Query: 484  QIYSGG-----TYYFGGCPDKSFGSKCKSPL--GGFQGCMRLISISGKVVDLISVQQGSL 536
               + G       + GG P+       +      G +GC+RL+ ++ + ++L  +  G+ 
Sbjct: 1481 PSGTDGLNLDTDLFVGGVPEDQAAVALERTFVGAGLRGCIRLLDVNNQRLEL-GIGPGAA 1539

Query: 537  GNFSDLQIDSCGISDRCLPNYCEHGGECSQ-SWSTFHCNCTNTGYRGATC 585
               S   +  CG    CLPN C  G  C       FHC C   G  G TC
Sbjct: 1540 TRGSG--VGECG-DHPCLPNPCHGGAPCQNLEAGRFHCQCP-PGRVGPTC 1585



 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 72/281 (25%), Positives = 112/281 (39%), Gaps = 33/281 (11%)

Query: 821  FKTTASSGVFLENL----GIADFIRIELRSPTVVTFSFDVGNGPFEISVQSPTHFNDNQW 876
            F     SG+ L N     G  DF+ + LR   +  F +D+G G   I  + P       W
Sbjct: 1668 FLARGPSGLLLYNGQKTDGKGDFVSLALRDRRL-EFRYDLGKGAAVIRSREPVTLG--AW 1724

Query: 877  HHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFVGGT---------ATRQRG 927
              V +ERN ++ +L+V    P+        H +L L   L+VGG          A    G
Sbjct: 1725 TRVSLERNGRKGALRVGD-GPRVLGESPVPHTVLNLKEPLYVGGAPDFSKLARAAAVSSG 1783

Query: 928  FLGCIRSLQLNGMTLDLEERAQVTPEVQPGCRGHCS-SYGKLCRNGGKCRERPIGFFCDC 986
            F G I+ + L G  L   E      +V       C+ + G  C NG  C  R   + C C
Sbjct: 1784 FDGAIQLVSLGGRQLLTPEHVLRQVDVTSFAGHPCTRASGHPCLNGASCVPREAAYVCLC 1843

Query: 987  TFSAYTGPFCSNE-ISAYFGSGSSVIYNFQE--NYLLSKNSSSHAASFHGDMKLSREMIK 1043
                ++GP C    +    G   ++ ++ +    YL +   S  A        L     +
Sbjct: 1844 P-GGFSGPHCEKGLVEKSAGDVDTLAFDGRTFVEYLNAVTESEKA--------LQSNHFE 1894

Query: 1044 FSFRTTRTPSLLLFVSSFYK--EYLSVIIAKNGSLQIRYKL 1082
             S RT  T  L+L+     +  +Y+++ I  +G LQ+ Y L
Sbjct: 1895 LSLRTEATQGLVLWSGKATERADYVALAIV-DGHLQLSYNL 1934



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 34/114 (29%), Positives = 53/114 (46%), Gaps = 13/114 (11%)

Query: 853  SFDVGNGPFEISVQSPTHFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQL 912
            S+++G+ P  + ++S    N N+W  V   R  +E SLQV    P T  +P  G   L  
Sbjct: 1931 SYNLGSQP--VVLRSTVPVNTNRWLRVVAHREQREGSLQVGNEAPVTGSSPL-GATQLDT 1987

Query: 913  NSQLFVGG----------TATRQRGFLGCIRSLQLNGMTLDLEERAQVTPEVQP 956
            +  L++GG                GF+GC+R + +    L L E A   PE++P
Sbjct: 1988 DGALWLGGLPELPVGPALPKAYGTGFVGCLRDVVVGRHPLHLLEDAVTKPELRP 2041



 Score = 44.3 bits (103), Expect = 8e-04
 Identities = 51/211 (24%), Positives = 93/211 (44%), Gaps = 17/211 (8%)

Query: 390  EEVSATFQFRTWNKAGLLLFSELQLISGG--ILLFLSDGKLKSNLYQPGKLPSDITAGVE 447
            E+++    F     +GLLL++  +    G  + L L D +L+   Y  GK  + I +   
Sbjct: 1660 EKMALEVVFLARGPSGLLLYNGQKTDGKGDFVSLALRDRRLEFR-YDLGKGAAVIRSREP 1718

Query: 448  LNDGQWHSVSL--SAKKNHLSVAVDGQMASAAPLLGPEQIYS-GGTYYFGGCPDKSFGSK 504
            +  G W  VSL  + +K  L V    ++   +P+  P  + +     Y GG PD S  ++
Sbjct: 1719 VTLGAWTRVSLERNGRKGALRVGDGPRVLGESPV--PHTVLNLKEPLYVGGAPDFSKLAR 1776

Query: 505  CKSPLGGFQGCMRLISISGK--VVDLISVQQGSLGNFSDLQIDSCGISDRCLPNYCEHGG 562
              +   GF G ++L+S+ G+  +     ++Q  + +F+      C    R   + C +G 
Sbjct: 1777 AAAVSSGFDGAIQLVSLGGRQLLTPEHVLRQVDVTSFAG---HPC---TRASGHPCLNGA 1830

Query: 563  ECSQSWSTFHCNCTNTGYRGATCHNSIYEQS 593
             C    + + C C   G+ G  C   + E+S
Sbjct: 1831 SCVPREAAYVCLCPG-GFSGPHCEKGLVEKS 1860


>gi|167830475 milk fat globule-EGF factor 8 protein isoform a [Homo
           sapiens]
          Length = 387

 Score = 80.9 bits (198), Expect = 7e-15
 Identities = 51/160 (31%), Positives = 82/160 (51%), Gaps = 15/160 (9%)

Query: 31  CDDPLV---SALPQASFSSSSELSS------SHGPGFARLNRRDGAGGWSPLVSNKYQWL 81
           C +PL    +++P    ++SS   +      S  P +ARL+++     W        QWL
Sbjct: 230 CANPLGLKNNSIPDKQITASSSYKTWGLHLFSWNPSYARLDKQGNFNAWVAGSYGNDQWL 289

Query: 82  QIDLGERMEVTAVATQG--GYGSSNWVTSYLLMFSDSGWNWKQYR--QEDSIWGFSGNAN 137
           Q+DLG   EVT + TQG   +GS  +V SY + +S+   NW +Y+  +  S   F GN +
Sbjct: 290 QVDLGSSKEVTGIITQGARNFGSVQFVASYKVAYSNDSANWTEYQDPRTGSSKIFPGNWD 349

Query: 138 ADSVVYYRLQPSIKARFLRFIPLEWNPKGRIGMRIEVFGC 177
             S      +  I AR++R +P+ W+   RI +R+E+ GC
Sbjct: 350 NHSHKKNLFETPILARYVRILPVAWH--NRIALRLELLGC 387



 Score = 51.6 bits (122), Expect = 5e-06
 Identities = 35/131 (26%), Positives = 64/131 (48%), Gaps = 17/131 (12%)

Query: 56  PGFARLNRRDGAGGWSPLVSNKYQWLQIDLGERMEVTAVATQGG--YGSSNWVTSYLLMF 113
           P  ARLNR      W+P  ++   W+Q++L  RM VT V TQG     S  ++ ++ + +
Sbjct: 103 PELARLNRAGMVNAWTPSSNDDNPWIQVNLLRRMWVTGVVTQGASRLASHEYLKAFKVAY 162

Query: 114 SDSGWNW-------KQYRQEDSIWGFSGNANADSVVYYRLQPSIKARFLRFIPLEWNPKG 166
           S +G  +       K++++      F GN N ++V     +  ++A+++R  P   +   
Sbjct: 163 SLNGHEFDFIHDVNKKHKE------FVGNWNKNAVHVNLFETPVEAQYVRLYPTSCHT-- 214

Query: 167 RIGMRIEVFGC 177
              +R E+ GC
Sbjct: 215 ACTLRFELLGC 225


>gi|10518506 coagulation factor VIII isoform b precursor [Homo
           sapiens]
          Length = 216

 Score = 80.1 bits (196), Expect = 1e-14
 Identities = 50/155 (32%), Positives = 78/155 (50%), Gaps = 10/155 (6%)

Query: 31  CDDPL---VSALPQASFSSSS---ELSSSHGPGFARLNRRDGAGGWSPLVSNKYQWLQID 84
           C  PL     A+  A  ++SS    + ++  P  ARL+ +  +  W P V+N  +WLQ+D
Sbjct: 58  CSMPLGMESKAISDAQITASSYFTNMFATWSPSKARLHLQGRSNAWRPQVNNPKEWLQVD 117

Query: 85  LGERMEVTAVATQG--GYGSSNWVTSYLLMFSDSGWNWKQYRQEDSIWGFSGNANADSVV 142
             + M+VT V TQG     +S +V  +L+  S  G  W  + Q   +  F GN ++ + V
Sbjct: 118 FQKTMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLFFQNGKVKVFQGNQDSFTPV 177

Query: 143 YYRLQPSIKARFLRFIPLEWNPKGRIGMRIEVFGC 177
              L P +  R+LR  P  W    +I +R+EV GC
Sbjct: 178 VNSLDPPLLTRYLRIHPQSW--VHQIALRMEVLGC 210


>gi|4503647 coagulation factor VIII isoform a precursor [Homo sapiens]
          Length = 2351

 Score = 80.1 bits (196), Expect = 1e-14
 Identities = 50/155 (32%), Positives = 78/155 (50%), Gaps = 10/155 (6%)

Query: 31   CDDPL---VSALPQASFSSSS---ELSSSHGPGFARLNRRDGAGGWSPLVSNKYQWLQID 84
            C  PL     A+  A  ++SS    + ++  P  ARL+ +  +  W P V+N  +WLQ+D
Sbjct: 2193 CSMPLGMESKAISDAQITASSYFTNMFATWSPSKARLHLQGRSNAWRPQVNNPKEWLQVD 2252

Query: 85   LGERMEVTAVATQG--GYGSSNWVTSYLLMFSDSGWNWKQYRQEDSIWGFSGNANADSVV 142
              + M+VT V TQG     +S +V  +L+  S  G  W  + Q   +  F GN ++ + V
Sbjct: 2253 FQKTMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLFFQNGKVKVFQGNQDSFTPV 2312

Query: 143  YYRLQPSIKARFLRFIPLEWNPKGRIGMRIEVFGC 177
               L P +  R+LR  P  W    +I +R+EV GC
Sbjct: 2313 VNSLDPPLLTRYLRIHPQSW--VHQIALRMEVLGC 2345



 Score = 58.9 bits (141), Expect = 3e-08
 Identities = 36/130 (27%), Positives = 64/130 (49%), Gaps = 8/130 (6%)

Query: 56   PGFARLNRRDGAGGWSPLVSNKYQWLQIDLGERMEVTAVATQGGYG--SSNWVTSYLLMF 113
            P  ARL+       WS      + W+++DL   M +  + TQG     SS +++ +++M+
Sbjct: 2067 PKLARLHYSGSINAWS--TKEPFSWIKVDLLAPMIIHGIKTQGARQKFSSLYISQFIIMY 2124

Query: 114  SDSGWNWKQYRQEDS--IWGFSGNANADSVVYYRLQPSIKARFLRFIPLEWNPKGRIGMR 171
            S  G  W+ YR   +  +  F GN ++  + +    P I AR++R  P  ++   R  +R
Sbjct: 2125 SLDGKKWQTYRGNSTGTLMVFFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSI--RSTLR 2182

Query: 172  IEVFGCAYRS 181
            +E+ GC   S
Sbjct: 2183 MELMGCDLNS 2192


>gi|54792129 discoidin, CUB and LCCL domain containing 2 [Homo
           sapiens]
          Length = 775

 Score = 79.7 bits (195), Expect = 2e-14
 Identities = 54/183 (29%), Positives = 87/183 (47%), Gaps = 12/183 (6%)

Query: 3   SVTGAVLKTLLLLSTQNWNRVEAGNSYDCDDPLVSALPQASFSSSSELSSSHGPGFARLN 62
           SV G +  +L    T          S    DP ++A     ++  +   +S  P  ARL 
Sbjct: 275 SVVGHLSTSLFTFKTSGCYGTLGMESGVIADPQITASSVLEWTDHTGQENSWKPKKARLK 334

Query: 63  RRDGAGGWSPLVSNKYQWLQIDLGERMEVTAVATQGG--YGSSNWVTSYLLMFSDSGWNW 120
           +      W+   +++YQWLQIDL +  ++T + T G      + +V++Y +++SD G  W
Sbjct: 335 KPGPP--WAAFATDEYQWLQIDLNKEKKITGIITTGSTMVEHNYYVSAYRILYSDDGQKW 392

Query: 121 KQYR----QEDSIWGFSGNANADSVVYYRLQPSIKARFLRFIPLEWNPKGRIGMRIEVFG 176
             YR    ++D I  F GN +    V     P I ARF+R  P +W  K  I M++E+ G
Sbjct: 393 TVYREPGVEQDKI--FQGNKDYHQDVRNNFLPPIIARFIRVNPTQWQQK--IAMKMELLG 448

Query: 177 CAY 179
           C +
Sbjct: 449 CQF 451


>gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens]
          Length = 4588

 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 62/183 (33%), Positives = 86/183 (46%), Gaps = 29/183 (15%)

Query: 852  FSFDVGNGPFEISVQSPTHFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQ 911
            + FD G+GP  +SVQS    ND QWH V +E N   A L +DQ+   +  AP      L 
Sbjct: 3888 YKFDCGSGPGIVSVQS-IQVNDGQWHAVALEVNGNYARLVLDQVHTASGTAPGTLKT-LN 3945

Query: 912  LNSQLFVGGTATRQ-----------RGFLGCIRSLQLNGMTLDLEER------AQVTPEV 954
            L++ +F GG   +Q            GF GC+ S+ LNG  L L  +       + + +V
Sbjct: 3946 LDNYVFFGGHIRQQGTRHGRSPQVGNGFRGCMDSIYLNGQELPLNSKPRSYAHIEESVDV 4005

Query: 955  QPGC----RGHCSSYGKLCRNGGKCRERPI-GFFCDCTFSAYTGPFCSNEISAYFGSGSS 1009
             PGC       C+S    C+NGG C   P  G++C C+ + Y G  C  EIS    S   
Sbjct: 4006 SPGCFLTATEDCAS--NPCQNGGVCNPSPAGGYYCKCS-ALYIGTHC--EISVNPCSSKP 4060

Query: 1010 VIY 1012
             +Y
Sbjct: 4061 CLY 4063



 Score = 66.6 bits (161), Expect = 1e-10
 Identities = 62/268 (23%), Positives = 122/268 (45%), Gaps = 14/268 (5%)

Query: 330  HGCLENLYYNGVDIIDLAKQQKPQIIAMGNVSFSCSQPQSMPVTFLSSRSYLALPDFSGE 389
            HGC ++    G + +    ++K   +        C    SM +T  S   Y  L +   +
Sbjct: 3792 HGCEDDPCPEGSECVSDPWEEKHTCVCPSGRFGQCPGSSSMTLTGNSYVKY-RLTENENK 3850

Query: 390  EEVSATFQFRTWNKAGLLLFSELQLISGGILLFLSDGKLKSNLYQPGKLPSDITA-GVEL 448
             E+  T + RT++   +++++     S   +L +  G+L+   +  G  P  ++   +++
Sbjct: 3851 LEMKLTMRLRTYSTHAVVMYARGTDYS---ILEIHHGRLQYK-FDCGSGPGIVSVQSIQV 3906

Query: 449  NDGQWHSVSLSAKKNHLSVAVDGQMASAAPLLGPEQIYSGGTYYFGGCPDKSFGSK-CKS 507
            NDGQWH+V+L    N+  + +D    ++    G  +  +   Y F G   +  G++  +S
Sbjct: 3907 NDGQWHAVALEVNGNYARLVLDQVHTASGTAPGTLKTLNLDNYVFFGGHIRQQGTRHGRS 3966

Query: 508  PL--GGFQGCMRLISISGKVVDLISVQQGSLGNFSDLQID-SCGI--SDRCLPNYCEHGG 562
            P    GF+GCM  I ++G+ + L S  +        + +   C +  ++ C  N C++GG
Sbjct: 3967 PQVGNGFRGCMDSIYLNGQELPLNSKPRSYAHIEESVDVSPGCFLTATEDCASNPCQNGG 4026

Query: 563  ECSQS-WSTFHCNCTNTGYRGATCHNSI 589
             C+ S    ++C C+   Y G  C  S+
Sbjct: 4027 VCNPSPAGGYYCKCSAL-YIGTHCEISV 4053



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 39/175 (22%), Positives = 80/175 (45%), Gaps = 16/175 (9%)

Query: 175  FGCAYRSEVVDLDGKSSLLYRFDQKSLSPIKDIISLKFKTMQSDGILLHREGPNGDHITL 234
            FG    S  + L G S + YR  +   + ++  ++++ +T  +  ++++  G   D+  L
Sbjct: 3823 FGQCPGSSSMTLTGNSYVKYRLTENE-NKLEMKLTMRLRTYSTHAVVMYARGT--DYSIL 3879

Query: 235  QLRRARLFLLINSGEAKLPSTSTLVNLTLGSLLDDQHWHSVLIQRLGKQVNFTVDE-HRH 293
            ++   RL    + G    P   ++ ++ +    +D  WH+V ++  G      +D+ H  
Sbjct: 3880 EIHHGRLQYKFDCGSG--PGIVSVQSIQV----NDGQWHAVALEVNGNYARLVLDQVHTA 3933

Query: 294  HFHARGEFNLMNLDYEISFGGI-----PAPGKSVSFPHRNFHGCLENLYYNGVDI 343
               A G    +NLD  + FGG         G+S    +  F GC++++Y NG ++
Sbjct: 3934 SGTAPGTLKTLNLDNYVFFGGHIRQQGTRHGRSPQVGN-GFRGCMDSIYLNGQEL 3987



 Score = 39.7 bits (91), Expect = 0.019
 Identities = 16/42 (38%), Positives = 23/42 (54%), Gaps = 1/42 (2%)

Query: 551  DRCLPNYCEHGGECSQSWSTFHCNCTNTGYRGATCHNSIYEQ 592
            D C  N C HG  C  +  ++HCNC++  YRG  C ++   Q
Sbjct: 4129 DECSGNPCLHGALCENTHGSYHCNCSHE-YRGRHCEDAAPNQ 4169



 Score = 38.1 bits (87), Expect = 0.056
 Identities = 22/65 (33%), Positives = 30/65 (46%), Gaps = 4/65 (6%)

Query: 547  CGISDRCLPNYCEHGGECSQSWSTFHCNCTNTGYRGATCHNSIYEQSCEAYKHRG---NT 603
            C +S  C    C++GG C  S     C C ++G+RG  C + I E S     H     NT
Sbjct: 4087 CQLSPYCKDEPCKNGGTCFDSLDGAVCQC-DSGFRGERCQSDIDECSGNPCLHGALCENT 4145

Query: 604  SGFYY 608
             G Y+
Sbjct: 4146 HGSYH 4150



 Score = 35.4 bits (80), Expect = 0.36
 Identities = 52/229 (22%), Positives = 84/229 (36%), Gaps = 39/229 (17%)

Query: 952  PEVQPGCRGHCSSYGKLCRNGGKCRERPIGFFCDCTFSAYTGPFCSNEISAYFGSGSSVI 1011
            P V  GC          C  G +C   P      C   +     C    S      S V 
Sbjct: 3788 PPVHHGCEDDP------CPEGSECVSDPWEEKHTCVCPSGRFGQCPGSSSMTLTGNSYVK 3841

Query: 1012 YNFQENYLLSKNSSSHAASFHGDMKLSREMIKFSFRTTRTPSLLLFVSSFYKEYLSVIIA 1071
            Y   EN    +N          +MKL+  +     RT  T +++++      +Y S++  
Sbjct: 3842 YRLTEN----ENKL--------EMKLTMRL-----RTYSTHAVVMYARG--TDY-SILEI 3881

Query: 1072 KNGSLQIRYKLNKYQEPDVVNFDFKNMADGQLHHIMINREEGVVFIEIDDNRRRQVHLSS 1131
             +G LQ  YK +    P +V+     + DGQ H + +        + +D     QVH +S
Sbjct: 3882 HHGRLQ--YKFDCGSGPGIVSVQSIQVNDGQWHAVALEVNGNYARLVLD-----QVHTAS 3934

Query: 1132 GTEFSAVKSLVL------GRILEHSDVDQDTALAGAQGFTGCLSAVQLS 1174
            GT    +K+L L      G  +         +     GF GC+ ++ L+
Sbjct: 3935 GTAPGTLKTLNLDNYVFFGGHIRQQGTRHGRSPQVGNGFRGCMDSIYLN 3983


>gi|62420886 discoidin domain receptor family, member 2 precursor
           [Homo sapiens]
          Length = 855

 Score = 74.7 bits (182), Expect = 5e-13
 Identities = 47/177 (26%), Positives = 83/177 (46%), Gaps = 8/177 (4%)

Query: 39  LPQASFSSSSELSSSHGPGFARLNRRDGAGGWSPLV----SNKYQWLQIDLGERMEVTAV 94
           +P    ++SS+ S S    + RL+  +G G W P +     +  ++LQIDL     +T V
Sbjct: 41  IPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLV 100

Query: 95  ATQGGYGSSNWVT---SYLLMFSDSGWNWKQYRQEDSIWGFSGNANADSVVYYRLQPSIK 151
            TQG +   + +     Y + +S  G  W  +R         GN+N   +    L+P I 
Sbjct: 101 GTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIV 160

Query: 152 ARFLRFIPLEWNPKGRIGMRIEVFGCAYRSEVVDLDGKSSLLYRFDQKSLSPIKDII 208
           ARF+RFIP+  +    + MR+E++GC +   +V  +  +   +     S+  + D +
Sbjct: 161 ARFVRFIPVT-DHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSV 216


>gi|62420884 discoidin domain receptor family, member 2 precursor
           [Homo sapiens]
          Length = 855

 Score = 74.7 bits (182), Expect = 5e-13
 Identities = 47/177 (26%), Positives = 83/177 (46%), Gaps = 8/177 (4%)

Query: 39  LPQASFSSSSELSSSHGPGFARLNRRDGAGGWSPLV----SNKYQWLQIDLGERMEVTAV 94
           +P    ++SS+ S S    + RL+  +G G W P +     +  ++LQIDL     +T V
Sbjct: 41  IPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLV 100

Query: 95  ATQGGYGSSNWVT---SYLLMFSDSGWNWKQYRQEDSIWGFSGNANADSVVYYRLQPSIK 151
            TQG +   + +     Y + +S  G  W  +R         GN+N   +    L+P I 
Sbjct: 101 GTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIV 160

Query: 152 ARFLRFIPLEWNPKGRIGMRIEVFGCAYRSEVVDLDGKSSLLYRFDQKSLSPIKDII 208
           ARF+RFIP+  +    + MR+E++GC +   +V  +  +   +     S+  + D +
Sbjct: 161 ARFVRFIPVT-DHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSV 216


>gi|38788416 laminin, alpha 1 precursor [Homo sapiens]
          Length = 3075

 Score = 74.3 bits (181), Expect = 7e-13
 Identities = 79/349 (22%), Positives = 147/349 (42%), Gaps = 34/349 (9%)

Query: 186  LDGKSSLLYRFDQKSLSPIKDIISLKFKTMQSDGILLHREGPN-GDHITLQLRRARLFLL 244
            L   S  +  F+Q ++   K  + L  +T  S G++ +    N  D+  LQL   RL  +
Sbjct: 2718 LTQNSHFILPFNQSAVRK-KLSVELSIRTFASSGLIYYMAHQNQADYAVLQLHGGRLHFM 2776

Query: 245  INSGEAKLPSTSTLVNLTLGSLLDDQHWHSVLIQRLGKQVNFTVDEHRHHF-HARGEFNL 303
             + G+ +         ++  +LL D  WH+V    + ++   TVD          G+  +
Sbjct: 2777 FDLGKGR-------TKVSHPALLSDGKWHTVKTDYVKRKGFITVDGRESPMVTVVGDGTM 2829

Query: 304  MNLDYEISFGGIPAP--GKSVSFPHRNFHGCLENLYYNGVDIIDLAKQQKPQIIAMGNVS 361
            ++++     GG+P+    + +     +   C+ ++  N   +     +  P      N  
Sbjct: 2830 LDVEGLFYLGGLPSQYQARKIGNITHSIPACIGDVTVNSKQL----DKDSPVSAFTVNRC 2885

Query: 362  FSCSQPQSMPVTFLSSRSYLAL--PDFSGEEEVSATFQFRTWNKAGLLLFSELQLISGGI 419
            ++ +Q      T+     Y AL    +  + +V+ T +FRT ++ G+LL      +   I
Sbjct: 2886 YAVAQEG----TYFDGSGYAALVKEGYKVQSDVNITLEFRTSSQNGVLLGISTAKVDA-I 2940

Query: 420  LLFLSDGKLKSNLYQPGKLPSDITAGVE------LNDGQWHSVSLSAKKNHLSVAVDGQM 473
             L L DGK+   L+        ITA  E      L DG+WH++  +  K+ +++ VDG  
Sbjct: 2941 GLELVDGKV---LFHVNNGAGRITAAYEPKTATVLCDGKWHTLQANKSKHRITLIVDGNA 2997

Query: 474  ASA-APLLGPEQIYSGGTYYFGGCPDKSFGSKCKSPLGGFQGCMRLISI 521
              A +P      + +    Y GG P      KC      F+GC+R +++
Sbjct: 2998 VGAESPHTQSTSVDTNNPIYVGGYP-AGVKQKCLRSQTSFRGCLRKLAL 3045



 Score = 70.9 bits (172), Expect = 8e-12
 Identities = 85/376 (22%), Positives = 158/376 (42%), Gaps = 52/376 (13%)

Query: 199  KSLSPIKDIISLKFKTMQSDGILL-----------HREGPNGDHITLQLRRARLFLLINS 247
            KSLSP  + + + F T  S GI+L            RE  +    ++ L    + + +N 
Sbjct: 2502 KSLSPESEWL-VTFATTNSSGIILAALGGDVEKRGDREEAHVPFFSVMLIGGNIEVHVNP 2560

Query: 248  GEAKLPSTSTLVNLTLGSLLDDQHWHSVLIQRLGKQVNFTVDEHRHHFHARG---EFNLM 304
            G+        L++   G+  D Q  HS+ + R  + +   +DE+       G   E   +
Sbjct: 2561 GDGT-GLRKALLHAPTGTCSDGQA-HSISLVRNRRIITVQLDENNPVEMKLGTLVESRTI 2618

Query: 305  NLDYEISFGGIP-APGKSVSFPHRNFHGCLENLYYN----------GVDIIDLAK---QQ 350
            N+   +  GGIP   G S+    R+FHGC++NL +N          G + +DL      +
Sbjct: 2619 NVS-NLYVGGIPEGEGTSLLTMRRSFHGCIKNLIFNLELLDFNSAVGHEQVDLDTCWLSE 2677

Query: 351  KPQIIAMGNVSFSCSQPQSMPVTF----------------LSSRSYLALP--DFSGEEEV 392
            +P++      S    +P++ P                   L+  S+  LP    +  +++
Sbjct: 2678 RPKLAPDAEDSKLLPEPRAFPEQCVVDAALEYVPGAHQFGLTQNSHFILPFNQSAVRKKL 2737

Query: 393  SATFQFRTWNKAGLLLFSELQLISGGILLFLSDGKLKSNLYQPGKLPSDITAGVELNDGQ 452
            S     RT+  +GL+ +   Q  +   +L L  G+L   ++  GK  + ++    L+DG+
Sbjct: 2738 SVELSIRTFASSGLIYYMAHQNQADYAVLQLHGGRLHF-MFDLGKGRTKVSHPALLSDGK 2796

Query: 453  WHSVSLSAKKNHLSVAVDGQMASAAPLLGPEQIYS-GGTYYFGGCPDKSFGSKCKSPLGG 511
            WH+V     K    + VDG+ +    ++G   +    G +Y GG P +    K  +    
Sbjct: 2797 WHTVKTDYVKRKGFITVDGRESPMVTVVGDGTMLDVEGLFYLGGLPSQYQARKIGNITHS 2856

Query: 512  FQGCMRLISISGKVVD 527
               C+  ++++ K +D
Sbjct: 2857 IPACIGDVTVNSKQLD 2872



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 38/145 (26%), Positives = 69/145 (47%), Gaps = 20/145 (13%)

Query: 817  VSFFFKTTASSGV--FLENLGIADFIRIELRSPTVVTFSFDVGNGPFEISVQSPTHFNDN 874
            +   F T + +G+  +L + G  DF+ IEL    V   + D+G+GP  I++ +   +N+ 
Sbjct: 2329 IIMLFNTFSPNGLLLYLGSYGTKDFLSIELFRGRVKVMT-DLGSGP--ITLLTDRRYNNG 2385

Query: 875  QWHHVRVERNMKEASLQV------DQLTPKTQPAPADGHVLLQLNSQ-LFVGGTATRQ-- 925
             W+ +  +RN K+  L V           K    P     L +L+   ++VGG    +  
Sbjct: 2386 TWYKIAFQRNRKQGVLAVIDAYNTSNKETKQGETPGASSDLNRLDKDPIYVGGLPRSRVV 2445

Query: 926  ------RGFLGCIRSLQLNGMTLDL 944
                  + F+GCI++L+++  T DL
Sbjct: 2446 RRGVTTKSFVGCIKNLEISRSTFDL 2470



 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 39/130 (30%), Positives = 61/130 (46%), Gaps = 17/130 (13%)

Query: 830  FLENLGIADFIRIELRSPTVVTFSFDVGNGPFEISVQSPTHFNDNQWHHVRVERNMKEAS 889
            +L +   +DF+ +E+R   V  F +D+G+G   +        +DN+WH + V R     S
Sbjct: 2157 YLGSSTASDFLAVEMRRGRVA-FLWDLGSGSTRLEFPD-FPIDDNRWHSIHVARFGNIGS 2214

Query: 890  LQVDQLT------PKTQPAPADGHVLLQLNSQL-FVGG--------TATRQRGFLGCIRS 934
            L V +++       KT  +P   +VL   NS L FVGG         A +   F GC+  
Sbjct: 2215 LSVKEMSSNQKSPTKTSKSPGTANVLDVNNSTLMFVGGLGGQIKKSPAVKVTHFKGCLGE 2274

Query: 935  LQLNGMTLDL 944
              LNG ++ L
Sbjct: 2275 AFLNGKSIGL 2284



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 76/355 (21%), Positives = 130/355 (36%), Gaps = 48/355 (13%)

Query: 208  ISLKFKTMQSDGILLHREGPNG-DHITLQLRRARLFLL--INSGEAKLPSTSTLVNLTLG 264
            ++L  KT + D +L +       D + +++RR R+  L  + SG  +L      +     
Sbjct: 2142 LTLNVKTQEPDNLLFYLGSSTASDFLAVEMRRGRVAFLWDLGSGSTRLEFPDFPI----- 2196

Query: 265  SLLDDQHWHSVLIQRLGKQVNFTVDEHRHH-------FHARGEFNLMNLDYE--ISFGGI 315
               DD  WHS+ + R G   + +V E   +         + G  N+++++    +  GG+
Sbjct: 2197 ---DDNRWHSIHVARFGNIGSLSVKEMSSNQKSPTKTSKSPGTANVLDVNNSTLMFVGGL 2253

Query: 316  PAP-GKSVSFPHRNFHGCLENLYYNGVDIIDLAKQQKPQIIAMGNVSFSCSQPQSMPVTF 374
                 KS +    +F GCL   + NG   I L    + +    G   F  SQ +  P   
Sbjct: 2254 GGQIKKSPAVKVTHFKGCLGEAFLNGKS-IGLWNYIEREGKCRG--CFGSSQNED-PSFH 2309

Query: 375  LSSRSYLALPDFSGEEEVSATFQFRTWNKAGLLLFSELQLISGGILLFLSDGKLKSNLYQ 434
                 Y  +              F T++  GLLL+         + + L  G++K  +  
Sbjct: 2310 FDGSGYSVVEKSLPATVTQIIMLFNTFSPNGLLLYLGSYGTKDFLSIELFRGRVKV-MTD 2368

Query: 435  PGKLPSDITAGVELNDGQWHSVSLSAKKNHLSVAV------------DGQMASAAPLLGP 482
             G  P  +      N+G W+ ++    +    +AV             G+   A+  L  
Sbjct: 2369 LGSGPITLLTDRRYNNGTWYKIAFQRNRKQGVLAVIDAYNTSNKETKQGETPGASSDLNR 2428

Query: 483  EQIYSGGTYYFGGCPDKSF---GSKCKSPLGGFQGCMRLISISGKVVDLISVQQG 534
                     Y GG P       G   KS    F GC++ + IS    DL+    G
Sbjct: 2429 ---LDKDPIYVGGLPRSRVVRRGVTTKS----FVGCIKNLEISRSTFDLLRNSYG 2476



 Score = 38.9 bits (89), Expect = 0.033
 Identities = 34/143 (23%), Positives = 65/143 (45%), Gaps = 17/143 (11%)

Query: 812  ELSADVSFFFKTTASSGV--FLENLGIADFIRIELRSPTVVTFSFDVGNGPFEISVQSPT 869
            +LS ++S   +T ASSG+  ++ +   AD+  ++L    +  F FD+G G  ++S   P 
Sbjct: 2736 KLSVELSI--RTFASSGLIYYMAHQNQADYAVLQLHGGRL-HFMFDLGKGRTKVS--HPA 2790

Query: 870  HFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFVGGTATRQR--- 926
              +D +WH V+ +   ++  + VD           DG  +L +    ++GG  ++ +   
Sbjct: 2791 LLSDGKWHTVKTDYVKRKGFITVDGRESPMVTVVGDG-TMLDVEGLFYLGGLPSQYQARK 2849

Query: 927  ------GFLGCIRSLQLNGMTLD 943
                      CI  + +N   LD
Sbjct: 2850 IGNITHSIPACIGDVTVNSKQLD 2872



 Score = 37.0 bits (84), Expect = 0.12
 Identities = 46/172 (26%), Positives = 67/172 (38%), Gaps = 23/172 (13%)

Query: 794  SASFDTEASYLHFPTFHGELSADVSFFFKTTASSGVFLENLGIADFIRIELRSPTVVTFS 853
            S SF  +  Y+  P       ++    F TT SSG+ L  LG     R +     V  FS
Sbjct: 2488 SVSF-LKGGYIELPPKSLSPESEWLVTFATTNSSGIILAALGGDVEKRGDREEAHVPFFS 2546

Query: 854  FDVGNGPFEISVQ-------------SPTHF-NDNQWHHVRVERNMKEASLQVDQLTPKT 899
              +  G  E+ V              +PT   +D Q H + + RN +  ++Q+D+  P  
Sbjct: 2547 VMLIGGNIEVHVNPGDGTGLRKALLHAPTGTCSDGQAHSISLVRNRRIITVQLDENNPVE 2606

Query: 900  QPAPADGHVLLQLNSQLFVGG--------TATRQRGFLGCIRSLQLNGMTLD 943
                          S L+VGG          T +R F GCI++L  N   LD
Sbjct: 2607 MKLGTLVESRTINVSNLYVGGIPEGEGTSLLTMRRSFHGCIKNLIFNLELLD 2658


>gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo
           sapiens]
          Length = 1158

 Score = 73.6 bits (179), Expect = 1e-12
 Identities = 47/142 (33%), Positives = 66/142 (46%), Gaps = 11/142 (7%)

Query: 46  SSSELSSSHGPGFARLNRRDGA-------GGWSPLVSNKYQWLQIDLGERMEVTAVATQG 98
           +SS L    G    RLN + GA       G W      + QW+++D       T V TQG
Sbjct: 402 ASSMLRHGLGAQRGRLNMQTGATEDDYYDGAWCAEDDARTQWIEVDTRRTTRFTGVITQG 461

Query: 99  GYGS--SNWVTSYLLMFSDSGWNWKQYRQEDSIWGFSGNANADSVVYYRLQPSIKARFLR 156
              S   ++VT++ + FS+    W  Y        F GN + D+ V   L   + ARF+R
Sbjct: 462 RDSSIHDDFVTTFFVGFSNDSQTWVMYTNGYEEMTFHGNVDKDTPVLSELPEPVVARFIR 521

Query: 157 FIPLEWNPKGRIGMRIEVFGCA 178
             PL WN  G + MR+EV GC+
Sbjct: 522 IYPLTWN--GSLCMRLEVLGCS 541


>gi|33469935 EGF-like, fibronectin type III and laminin G domains
            isoform 3 [Homo sapiens]
          Length = 375

 Score = 73.6 bits (179), Expect = 1e-12
 Identities = 97/388 (25%), Positives = 144/388 (37%), Gaps = 76/388 (19%)

Query: 821  FKTTASSGVFLENL--GIADFIRIELRSPTVVTFSFDVGNGPFEISVQSPTHFNDNQWHH 878
            F+  +  GV L +   G  DF+ I L    V  F FD G+G   +  + P    +  WH 
Sbjct: 7    FRPDSGDGVLLYSYDTGSKDFLSINLAGGHV-EFRFDCGSGTGVLRSEDPLTLGN--WHE 63

Query: 879  VRVERNMKEASLQVDQLTPKTQPAPADG-HVLLQLNSQLFVGGTATRQ---------RGF 928
            +RV R  K   LQVD+   K     A+G    ++ N+ +F+GG              + F
Sbjct: 64   LRVSRTAKNGILQVDK--QKIVEGMAEGGFTQIKCNTDIFIGGVPNYDDVKKNSGVLKPF 121

Query: 929  LGCIRSLQLNGMTL----DLEERAQVTPEVQPGCRGHCSSYGKLCRNGGKCRERPIGFFC 984
             G I+ + LN  T+    D      V     P  R  C+       +GG CR R  G+ C
Sbjct: 122  SGSIQKIILNDRTIHVKHDFTSGVNVENAAHPCVRAPCA-------HGGSCRPRKEGYDC 174

Query: 985  DCTFSAYTGPFCSN------EISAYFGSGSSVIYNFQENYLLSKNSSSHAASFHGDMKLS 1038
            DC    + G  C        EI  + G      Y   +N  + K  S            S
Sbjct: 175  DCPL-GFEGLHCQKAIIEAIEIPQFIGRS----YLTYDNPDILKRVSG-----------S 218

Query: 1039 REMIKFSFRTTRTPSLLLFVSSFYKEYLSVIIA---KNGSLQIRYKLNKYQEPDVVNFDF 1095
            R  +   F+TT    LLL+         S  I+   ++G+L   Y L       +VN  F
Sbjct: 219  RSNVFMRFKTTAKDGLLLWRGDSPMRPNSDFISLGLRDGALVFSYNLGSGVASIMVNGSF 278

Query: 1096 KNMADGQLHHIMINREEGVVFIEIDD---------NRRRQVHLSSGTEFSAVKSLVLGRI 1146
                DG+ H +   R+     I +DD            RQ++++       +K + L   
Sbjct: 279  N---DGRWHRVKAVRDGQSGKITVDDYGARTGKSPGMMRQLNINGALYVGGMKEIAL--- 332

Query: 1147 LEHSDVDQDTALAGAQGFTGCLSAVQLS 1174
                     T     +G  GC+S   LS
Sbjct: 333  --------HTNRQYMRGLVGCISHFTLS 352



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 45/137 (32%), Positives = 66/137 (48%), Gaps = 17/137 (12%)

Query: 815 ADVSFFFKTTASSGVFLENLGI-----ADFIRIELRSPTVVTFSFDVGNGPFEISVQSPT 869
           ++V   FKTTA  G+ L          +DFI + LR   +V FS+++G+G   I V    
Sbjct: 220 SNVFMRFKTTAKDGLLLWRGDSPMRPNSDFISLGLRDGALV-FSYNLGSGVASIMVNGS- 277

Query: 870 HFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFVGGT------AT 923
            FND +WH V+  R+ +   + VD    +T  +P      L +N  L+VGG         
Sbjct: 278 -FNDGRWHRVKAVRDGQSGKITVDDYGARTGKSPGMMR-QLNINGALYVGGMKEIALHTN 335

Query: 924 RQ--RGFLGCIRSLQLN 938
           RQ  RG +GCI    L+
Sbjct: 336 RQYMRGLVGCISHFTLS 352



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 83/359 (23%), Positives = 136/359 (37%), Gaps = 57/359 (15%)

Query: 210 LKFKTMQSDGILLHR-EGPNGDHITLQLRRARLFLLIN--SGEAKLPSTSTLVNLTLGSL 266
           + F+    DG+LL+  +  + D +++ L    +    +  SG   L S   L   TLG+ 
Sbjct: 5   ITFRPDSGDGVLLYSYDTGSKDFLSINLAGGHVEFRFDCGSGTGVLRSEDPL---TLGN- 60

Query: 267 LDDQHWHSVLIQRLGKQVNFTVDEHRH-HFHARGEFNLMNLDYEISFGGIPAPG--KSVS 323
                WH + + R  K     VD+ +     A G F  +  + +I  GG+P     K  S
Sbjct: 61  -----WHELRVSRTAKNGILQVDKQKIVEGMAEGGFTQIKCNTDIFIGGVPNYDDVKKNS 115

Query: 324 FPHRNFHGCLENLYYN------------GVDIIDLAKQQKPQIIAMGNV------SFSCS 365
              + F G ++ +  N            GV++ + A        A G         + C 
Sbjct: 116 GVLKPFSGSIQKIILNDRTIHVKHDFTSGVNVENAAHPCVRAPCAHGGSCRPRKEGYDCD 175

Query: 366 QP-------------QSMPVTFLSSRSYLALPDFSGEEEVSAT-----FQFRTWNKAGLL 407
            P             +++ +     RSYL   +    + VS +      +F+T  K GLL
Sbjct: 176 CPLGFEGLHCQKAIIEAIEIPQFIGRSYLTYDNPDILKRVSGSRSNVFMRFKTTAKDGLL 235

Query: 408 LF---SELQLISGGILLFLSDGKLKSNLYQPGKLPSDITAGVELNDGQWHSVSLSAKKNH 464
           L+   S ++  S  I L L DG L  + Y  G   + I      NDG+WH V        
Sbjct: 236 LWRGDSPMRPNSDFISLGLRDGALVFS-YNLGSGVASIMVNGSFNDGRWHRVKAVRDGQS 294

Query: 465 LSVAVDGQMASAAPLLG-PEQIYSGGTYYFGGCPDKSFGSKCKSPLGGFQGCMRLISIS 522
             + VD   A      G   Q+   G  Y GG  + +  +  +  + G  GC+   ++S
Sbjct: 295 GKITVDDYGARTGKSPGMMRQLNINGALYVGGMKEIALHTN-RQYMRGLVGCISHFTLS 352



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 39/141 (27%), Positives = 62/141 (43%), Gaps = 14/141 (9%)

Query: 182 EVVDLDGKSSLLYRFDQ--KSLSPIKDIISLKFKTMQSDGILLHREG----PNGDHITLQ 235
           E+    G+S L Y      K +S  +  + ++FKT   DG+LL R      PN D I+L 
Sbjct: 194 EIPQFIGRSYLTYDNPDILKRVSGSRSNVFMRFKTTAKDGLLLWRGDSPMRPNSDFISLG 253

Query: 236 LRRARLFLLINSGEAKLPSTSTLVNLTLGSLLDDQHWHSVLIQRLGKQVNFTVDEH-RHH 294
           LR   L    N G       S + ++ +    +D  WH V   R G+    TVD++    
Sbjct: 254 LRDGALVFSYNLG-------SGVASIMVNGSFNDGRWHRVKAVRDGQSGKITVDDYGART 306

Query: 295 FHARGEFNLMNLDYEISFGGI 315
             + G    +N++  +  GG+
Sbjct: 307 GKSPGMMRQLNINGALYVGGM 327



 Score = 39.3 bits (90), Expect = 0.025
 Identities = 32/142 (22%), Positives = 56/142 (39%), Gaps = 10/142 (7%)

Query: 451 GQWHSVSLSAKKNHLSVAVDGQ-MASAAPLLGPEQIYSGGTYYFGGCPDKSFGSKCKSPL 509
           G WH + +S    +  + VD Q +       G  QI      + GG P+     K    L
Sbjct: 59  GNWHELRVSRTAKNGILQVDKQKIVEGMAEGGFTQIKCNTDIFIGGVPNYDDVKKNSGVL 118

Query: 510 GGFQGCMRLISISGKVVDLISVQQGSLGNFSDLQIDSCGISDRCLPNYCEHGGECSQSWS 569
             F G ++ I ++ + + +           S + +++   +  C+   C HGG C     
Sbjct: 119 KPFSGSIQKIILNDRTIHV------KHDFTSGVNVENA--AHPCVRAPCAHGGSCRPRKE 170

Query: 570 TFHCNCTNTGYRGATCHNSIYE 591
            + C+C   G+ G  C  +I E
Sbjct: 171 GYDCDCP-LGFEGLHCQKAIIE 191


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.411 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 50,827,772
Number of Sequences: 37866
Number of extensions: 2343295
Number of successful extensions: 7174
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 90
Number of HSP's successfully gapped in prelim test: 67
Number of HSP's that attempted gapping in prelim test: 5706
Number of HSP's gapped (non-prelim): 1094
length of query: 1308
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1194
effective length of database: 13,930,794
effective search space: 16633368036
effective search space used: 16633368036
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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