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Search of human proteins with 116235480
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|116235480 leucine zipper transcription regulator 2 [Homo
sapiens]
(1060 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|116235480 leucine zipper transcription regulator 2 [Homo sapi... 2195 0.0
gi|124378039 SEC16 homolog A [Homo sapiens] 479 e-135
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 50 1e-05
gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens] 47 1e-04
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 46 2e-04
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 45 5e-04
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 45 5e-04
gi|28559039 mediator complex subunit 1 [Homo sapiens] 44 8e-04
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 44 8e-04
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 44 8e-04
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 44 8e-04
gi|57222568 myeloid/lymphoid or mixed-lineage leukemia (trithora... 43 0.001
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] 43 0.002
gi|4885407 hyperpolarization activated cyclic nucleotide-gated p... 42 0.002
gi|30181233 leucine-rich repeats and calponin homology (CH) doma... 42 0.002
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 42 0.004
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ... 42 0.004
gi|57864582 hornerin [Homo sapiens] 41 0.005
gi|55769546 PAK1 interacting protein 1 [Homo sapiens] 41 0.005
gi|7657387 CCR4-NOT transcription complex, subunit 3 [Homo sapiens] 41 0.005
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 40 0.009
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 40 0.009
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 40 0.009
gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c ... 40 0.009
gi|51479192 ring finger protein 1 [Homo sapiens] 40 0.009
gi|166795264 AE binding protein 2 isoform b [Homo sapiens] 40 0.009
gi|166795262 AE binding protein 2 isoform a [Homo sapiens] 40 0.009
gi|195539337 S-adenosylhomocysteine hydrolase-like 2 isoform b [... 40 0.012
gi|118498345 AT-binding transcription factor 1 [Homo sapiens] 40 0.012
gi|163965366 nascent polypeptide-associated complex alpha subuni... 40 0.012
>gi|116235480 leucine zipper transcription regulator 2 [Homo sapiens]
Length = 1060
Score = 2195 bits (5687), Expect = 0.0
Identities = 1060/1060 (100%), Positives = 1060/1060 (100%)
Query: 1 MELWAPQRLPQTRGKATAPSKDPDRGFRRDGHHRPVPHSWHNGERFHQWQDNRGSPQPQQ 60
MELWAPQRLPQTRGKATAPSKDPDRGFRRDGHHRPVPHSWHNGERFHQWQDNRGSPQPQQ
Sbjct: 1 MELWAPQRLPQTRGKATAPSKDPDRGFRRDGHHRPVPHSWHNGERFHQWQDNRGSPQPQQ 60
Query: 61 EPRADHQQQPHYASRPGDWHQPVSGVDYYEGGYRNQLYSRPGYENSYQSYQSPTMREEYA 120
EPRADHQQQPHYASRPGDWHQPVSGVDYYEGGYRNQLYSRPGYENSYQSYQSPTMREEYA
Sbjct: 61 EPRADHQQQPHYASRPGDWHQPVSGVDYYEGGYRNQLYSRPGYENSYQSYQSPTMREEYA 120
Query: 121 YGSYYYHGHPQWLQEERVPRQRSPYIWHEDYREQKYLDEHHYENQHSPFGTNSETHFQSN 180
YGSYYYHGHPQWLQEERVPRQRSPYIWHEDYREQKYLDEHHYENQHSPFGTNSETHFQSN
Sbjct: 121 YGSYYYHGHPQWLQEERVPRQRSPYIWHEDYREQKYLDEHHYENQHSPFGTNSETHFQSN 180
Query: 181 SRNPCKDSPASNSGQEWPGELFPGSLLAEAQKNKPSLASESNLLQQRESGLSSSSYELSQ 240
SRNPCKDSPASNSGQEWPGELFPGSLLAEAQKNKPSLASESNLLQQRESGLSSSSYELSQ
Sbjct: 181 SRNPCKDSPASNSGQEWPGELFPGSLLAEAQKNKPSLASESNLLQQRESGLSSSSYELSQ 240
Query: 241 YIRDAPERDDPPASAAWSPVQADVSSAGPKAPMKFYIPHVPVSFGPGGQLVHVGPSSPTD 300
YIRDAPERDDPPASAAWSPVQADVSSAGPKAPMKFYIPHVPVSFGPGGQLVHVGPSSPTD
Sbjct: 241 YIRDAPERDDPPASAAWSPVQADVSSAGPKAPMKFYIPHVPVSFGPGGQLVHVGPSSPTD 300
Query: 301 GQAALVELHSMEVILNDSEEQEEMRSFSGPLIREDVHKVDIMTFCQQKAAQSCKSETLGS 360
GQAALVELHSMEVILNDSEEQEEMRSFSGPLIREDVHKVDIMTFCQQKAAQSCKSETLGS
Sbjct: 301 GQAALVELHSMEVILNDSEEQEEMRSFSGPLIREDVHKVDIMTFCQQKAAQSCKSETLGS 360
Query: 361 RDSALLWQLLVLLCRQNGSMVGSDIAELLMQDCKKLEKYKRQPPVANLINLTDEDWPVLS 420
RDSALLWQLLVLLCRQNGSMVGSDIAELLMQDCKKLEKYKRQPPVANLINLTDEDWPVLS
Sbjct: 361 RDSALLWQLLVLLCRQNGSMVGSDIAELLMQDCKKLEKYKRQPPVANLINLTDEDWPVLS 420
Query: 421 SGTPNLLTGEIPPSVETPAQIVEKFTRLLYYGRKKEALEWAMKNHLWGHALFLSSKMDPQ 480
SGTPNLLTGEIPPSVETPAQIVEKFTRLLYYGRKKEALEWAMKNHLWGHALFLSSKMDPQ
Sbjct: 421 SGTPNLLTGEIPPSVETPAQIVEKFTRLLYYGRKKEALEWAMKNHLWGHALFLSSKMDPQ 480
Query: 481 TYSWVMSGFTSTLALNDPLQTLFQLMSGRIPQAATCCGEKQWGDWRPHLAVILSNQAGDP 540
TYSWVMSGFTSTLALNDPLQTLFQLMSGRIPQAATCCGEKQWGDWRPHLAVILSNQAGDP
Sbjct: 481 TYSWVMSGFTSTLALNDPLQTLFQLMSGRIPQAATCCGEKQWGDWRPHLAVILSNQAGDP 540
Query: 541 ELYQRAIVAIGDTLAGKGLVEAAHFCYLMAHVPFGHYTVKTDHLVLLGSSHSQEFLKFAT 600
ELYQRAIVAIGDTLAGKGLVEAAHFCYLMAHVPFGHYTVKTDHLVLLGSSHSQEFLKFAT
Sbjct: 541 ELYQRAIVAIGDTLAGKGLVEAAHFCYLMAHVPFGHYTVKTDHLVLLGSSHSQEFLKFAT 600
Query: 601 TEAIQRTEIFEYCQMLGRPKSFIPSFQVYKLLYASRLADYGLVSQALHYCEAIGAAVLSQ 660
TEAIQRTEIFEYCQMLGRPKSFIPSFQVYKLLYASRLADYGLVSQALHYCEAIGAAVLSQ
Sbjct: 601 TEAIQRTEIFEYCQMLGRPKSFIPSFQVYKLLYASRLADYGLVSQALHYCEAIGAAVLSQ 660
Query: 661 GESSHPVLLVELIKLAEKLKLSDPLVLERRSGDRDLEPDWLAQLRRQLEQKVAGDIGDPH 720
GESSHPVLLVELIKLAEKLKLSDPLVLERRSGDRDLEPDWLAQLRRQLEQKVAGDIGDPH
Sbjct: 661 GESSHPVLLVELIKLAEKLKLSDPLVLERRSGDRDLEPDWLAQLRRQLEQKVAGDIGDPH 720
Query: 721 PTRSDISGAGGTTTENTFYQDFSGCQGYSEAPGYRSALWLTPEQTCLLQPSPQQPFPLQP 780
PTRSDISGAGGTTTENTFYQDFSGCQGYSEAPGYRSALWLTPEQTCLLQPSPQQPFPLQP
Sbjct: 721 PTRSDISGAGGTTTENTFYQDFSGCQGYSEAPGYRSALWLTPEQTCLLQPSPQQPFPLQP 780
Query: 781 GSYPAGGGAGQTGTPRPFYSVPETHLPGTGSSVAVTEATGGTVWEEMLQTHLGPGENTVS 840
GSYPAGGGAGQTGTPRPFYSVPETHLPGTGSSVAVTEATGGTVWEEMLQTHLGPGENTVS
Sbjct: 781 GSYPAGGGAGQTGTPRPFYSVPETHLPGTGSSVAVTEATGGTVWEEMLQTHLGPGENTVS 840
Query: 841 QETSQPPDGQEVISKPQTPLAARPRSISESSASSAKEDEKESSDEADKNSPRNTAQRGKL 900
QETSQPPDGQEVISKPQTPLAARPRSISESSASSAKEDEKESSDEADKNSPRNTAQRGKL
Sbjct: 841 QETSQPPDGQEVISKPQTPLAARPRSISESSASSAKEDEKESSDEADKNSPRNTAQRGKL 900
Query: 901 GDGKEHTKSSGFGWFSWFRSKPTKNASPAGDEDSSDSPDSEETPRASSPHQAGLGLSLTP 960
GDGKEHTKSSGFGWFSWFRSKPTKNASPAGDEDSSDSPDSEETPRASSPHQAGLGLSLTP
Sbjct: 901 GDGKEHTKSSGFGWFSWFRSKPTKNASPAGDEDSSDSPDSEETPRASSPHQAGLGLSLTP 960
Query: 961 SPESPPLPDVSAFSRGRGGGEGRGSASSGGAAAGAGVGGLSGPESVSFELCSNPGVLLPP 1020
SPESPPLPDVSAFSRGRGGGEGRGSASSGGAAAGAGVGGLSGPESVSFELCSNPGVLLPP
Sbjct: 961 SPESPPLPDVSAFSRGRGGGEGRGSASSGGAAAGAGVGGLSGPESVSFELCSNPGVLLPP 1020
Query: 1021 PALKGAVPLYNPSQVPQLPTATSLNRPNRLAQRRYPTQPC 1060
PALKGAVPLYNPSQVPQLPTATSLNRPNRLAQRRYPTQPC
Sbjct: 1021 PALKGAVPLYNPSQVPQLPTATSLNRPNRLAQRRYPTQPC 1060
>gi|124378039 SEC16 homolog A [Homo sapiens]
Length = 2357
Score = 479 bits (1233), Expect = e-135
Identities = 342/972 (35%), Positives = 479/972 (49%), Gaps = 102/972 (10%)
Query: 100 RPGYENSYQSYQSPTMREEYAYGSYYY----HGHP-QWLQEERVPRQRSPYIWHEDYREQ 154
R GY Y S +S + Y SYY +G P W + R R P + Y
Sbjct: 1235 RQGYPEGYYSSKSGWSSQSDYYASYYSSQYDYGDPGHWDRYHYSARVRDPRTYDRRYWCD 1294
Query: 155 KYLDEHHYENQHSPFGTNSETHFQSNSRNP-----CKDSPASNS---GQEWPGELFPGSL 206
D Y +HS FG E + +P D P + G+E
Sbjct: 1295 AEYDA--YRREHSAFGDRPEKRDNNWRYDPRFTGSFDDDPDPHRDPYGEEVDRRSVHSEH 1352
Query: 207 LAEAQKNKPSLASESNLLQQ--------RESGLSSSSYELS----------------QYI 242
A + + SLAS + L R +++ SYE
Sbjct: 1353 SARSLHSAHSLASRRSSLSSHSHQSQIYRSHNVAAGSYEAPLPPGSFHGDFAYGTYRSNF 1412
Query: 243 RDAPERDDP--PASAAWSPVQADVSSAGPKAPMKFYIPHVPVSFGPGGQLVHVGPSSPTD 300
P + PA W P VSS P +P KF +PHV FGPGGQL+ V P+ P++
Sbjct: 1413 SSGPGFPEYGYPADTVW-PAMEQVSSR-PTSPEKFSVPHVCARFGPGGQLIKVIPNLPSE 1470
Query: 301 GQAALVELHSMEVILNDSEEQEEMRSFSGPLIREDVHKVDIMTFCQQKAAQSCKSETLGS 360
GQ ALVE+HSME +L + EQEEMR+F GPL ++D HKVD++ F Q KA + ++E L
Sbjct: 1471 GQPALVEVHSMEALLQHTSEQEEMRAFPGPLAKDDTHKVDVINFAQNKAMKCLQNENLID 1530
Query: 361 RDSA-LLWQLLVLLCRQNGSMVGSDIAELLMQDCKKLEKYKRQPPVANLINLTDEDWPVL 419
++SA LLW +VLLCRQNG++VG+DIAELL++D + + + P ANLI+ T+E +
Sbjct: 1531 KESASLLWNFIVLLCRQNGTVVGTDIAELLLRDHRTVWLPGKSPNEANLIDFTNEAVEQV 1590
Query: 420 S---SGTPNL--LTGEIPPSVETPAQIVEKFTRLLYYGRKKEALEWAMKNHLWGHALFLS 474
SG L LTG + + + E+F LL YGRKK+ALE AMKN LWGHAL L+
Sbjct: 1591 EEEESGEAQLSFLTGGPAAAASSLERETERFRELLLYGRKKDALESAMKNGLWGHALLLA 1650
Query: 475 SKMDPQTYSWVMSGFTSTLALNDPLQTLFQLMSGRIPQAATCCGEKQWGDWRPHLAVILS 534
SKMD +T++ VM+ F ++L +NDPLQT++QLMSGR+P A+TCCG+++WGDWRPHLA++LS
Sbjct: 1651 SKMDSRTHARVMTRFANSLPINDPLQTVYQLMSGRMPAASTCCGDEKWGDWRPHLAMVLS 1710
Query: 535 NQAGDPELYQRAIVAIGDTLAGKGLVEAAHFCYLMAHVPFGHYTVKTDHLVLLGSSHSQE 594
N + ++ R + +GDTLA +GL++AAHFCYLMA FG YT KT LVL+GS+HS
Sbjct: 1711 NLNNNMDVESRTMATMGDTLASRGLLDAAHFCYLMAQAGFGVYTKKTTKLVLIGSNHSLP 1770
Query: 595 FLKFATTEAIQRTEIFEYCQMLGRPKSFIPSFQVYKLLYASRLADYGLVSQALHYCEAIG 654
FLKFAT EAIQRTE +EY Q LG +PSFQV+K +Y+ RLA+ GL +QA HYCEAI
Sbjct: 1771 FLKFATNEAIQRTEAYEYAQSLGAETCPLPSFQVFKFIYSCRLAEMGLATQAFHYCEAIA 1830
Query: 655 AAVLSQGESSHPVLLVELIKLAEKLKLSDPLVLERRSGDRDLEPDWLAQLRRQLEQKVAG 714
++L+Q PVL+ +L+++A +L+L DP + E+ + P WL L +Q+E+++
Sbjct: 1831 KSILTQPHLYSPVLISQLVQMASQLRLFDPQLKEKPEEESLAAPTWLVHL-QQVERQIKE 1889
Query: 715 DIGDPHPTRSDISGAGGTTTENTFYQDFSGCQGYSEAPGYRSALWLTP-------EQTCL 767
G H + GT + D G A G + L P +
Sbjct: 1890 GAGVWHQDGALPQQCPGTPSSEMEQLDRPGL-SQPGALGIANPLLAVPAPSPEHSSPSVR 1948
Query: 768 LQPS----------------PQQPFPLQPGSYPAGGGAGQTGTPRPFYSVPETHLPGTGS 811
L PS P P PL PG G G TP P E PG
Sbjct: 1949 LLPSAPQTLPDGPLASPARVPMFPVPLPPGPLEPGPGC---VTPGPALGFLEPSGPGLPP 2005
Query: 812 SVAVTEATGGTVWEEM-----LQTHLGPGENTVSQETSQPPDGQEVISKPQTPLAARPRS 866
V + + E + P N++S+ + + DG+ P +R
Sbjct: 2006 GVPPLQERRHLLQEARSPDPGIVPQEAPVGNSLSELSEENFDGKFANLTP-----SRTVP 2060
Query: 867 ISESSASSAKEDEKESSDEADKNSPRNTAQRGKLGDGKEHTKSSGFGW-FSWFRSK---- 921
SE+ + D + + T + G+ + G W F W K
Sbjct: 2061 DSEAPPGWDRADSGPTQPPLSLSPAPETKRPGQAAKKETKEPKKGESWFFRWLPGKKKTE 2120
Query: 922 ----PTKNASPAGDEDSS---DSPDSEETPRASSPHQAGLGLSLTPSPES---PPLPDVS 971
KN S DE + + + EE +A P + ++ +P + PP V+
Sbjct: 2121 AYLPDDKNKSIVWDEKKNQWVNLNEPEEEKKAPPPPPTSMPKTVQAAPPALPGPPGAPVN 2180
Query: 972 AFSRGRGGGEGR 983
+SR G R
Sbjct: 2181 MYSRRAAGTRAR 2192
Score = 39.3 bits (90), Expect = 0.020
Identities = 40/141 (28%), Positives = 59/141 (41%), Gaps = 18/141 (12%)
Query: 922 PTKNASPAGDEDSSDSPDSEETPRASSPHQAGLGLSLTPSPESPPLPDVSAFSRGRGGGE 981
P+ P D + PD T R GL +PE P P V + + G E
Sbjct: 2224 PSNLFVPTPDAEEPQLPDG--TGREGPAAARGLA-----NPEPAPEPKVLSSAASLPGSE 2276
Query: 982 GRGSASSGGAAAGAGVGGLSGPESVSFELCSN----PGVLLP---PPALKGAVPLYNPSQ 1034
S G + G + S S+S E+ + PG L PP+ GA+P YNP+Q
Sbjct: 2277 LPSSRPEG--SQGGELSRCSSMSSLSREVSQHFNQAPGDLPAAGGPPS--GAMPFYNPAQ 2332
Query: 1035 VPQLPTATSLNRPNRLAQRRY 1055
+ Q + +R R+ QR++
Sbjct: 2333 LAQACATSGSSRLGRIGQRKH 2353
Score = 31.2 bits (69), Expect = 5.4
Identities = 85/376 (22%), Positives = 126/376 (33%), Gaps = 88/376 (23%)
Query: 711 KVAGDI-GDPHPTRSDISGAGGTTTENTFYQDFSGCQGYSEAPGYRSALWLTPEQTCLLQ 769
+ AGD+ GD T + A G+ EN +F Q + P + L
Sbjct: 434 EAAGDVWGDTAST--GVPDASGSQYENVENLEFVQNQE------------VLPSEPLNLD 479
Query: 770 PS-PQQPF---PLQPGSYPAGGGAGQTGTP-RPFYSVPETHLPGTGSSVAVTEATGGTVW 824
PS P F PL + P G TG P ++V + + SS + +G
Sbjct: 480 PSSPSDQFRYGPLPGPAVPRHGAVCHTGAPDATLHTVHPDSVSSSYSSRSHGRLSGSARP 539
Query: 825 EEM----LQTHLGPGENTVS-----QETSQPPDGQE-----------VISKPQTPLAARP 864
+E+ +Q +G E+ S Q S P G+ +S+P TP +P
Sbjct: 540 QELVGTFIQQEVGKPEDEASGSFFKQIDSSPVGGETDETTVSQNYRGSVSQPSTPSPPKP 599
Query: 865 RSISESSASSAKEDEKE-----SSDEADK----NSPRNTAQRGKLGDGKEHTKSSGFGWF 915
I ++SA+S+ E K EAD+ R T R K
Sbjct: 600 TGIFQTSANSSFEPVKSHLVGVKPFEADRANVVGEVRETCVRQK---------------- 643
Query: 916 SWFRSKPTKNASPAGDEDSSDSPDSEETPRASSPHQAGLGLSLT-------PSPESPPLP 968
+ +P A + PD+ ET +P L L+ T P +PPL
Sbjct: 644 ---QCRPAAALPDASPGNLEQPPDNMET--LCAPQVCPLPLNSTTEAVHMLPHAGAPPLD 698
Query: 969 DVSAFSRGRGGGEGRGSASSGGAAA---------GAGVGGLSGPESVSFELCS--NPGVL 1017
V R +G A G L P + + +C+ P V+
Sbjct: 699 TVYPAPEKRPSARTQGPVKCESPATTLWAQSELPDFGGNVLLAPAAPALYVCAKPQPPVV 758
Query: 1018 LPPPALKGAVPLYNPS 1033
PP NPS
Sbjct: 759 QPPEEAMSGQQSRNPS 774
>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
Length = 1838
Score = 49.7 bits (117), Expect = 1e-05
Identities = 90/394 (22%), Positives = 129/394 (32%), Gaps = 75/394 (19%)
Query: 692 GDRDLEPDWLAQLRRQLEQKVAGDIGDPHPTRSDISGAGGTTTENTFYQDFSGCQGYSEA 751
G DLE ++ + R L++ DP + S+I G G ++T Y+ G +G
Sbjct: 396 GADDLEGEFTEETIRNLDENYYDPYYDPTSSPSEI-GPGMPANQDTIYEGIGGPRGEKGQ 454
Query: 752 PGYRSALWLTPEQTCLLQ--PSPQQPFPLQPGSYPAGGGAGQTGTPRPFYSVPETHLPGT 809
G + + E L++ P P+ P L PG G GQ G P LPG
Sbjct: 455 KGEPAII----EPGMLIEGPPGPEGPAGL-PGPPGTMGPTGQVGDPGERGPPGRPGLPGA 509
Query: 810 --------------------------GSSVAVTEATGGTVWEEM---LQTHLGPGENTVS 840
G V+ E+ + ++ L+ GP T
Sbjct: 510 DGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGR 569
Query: 841 QETSQPPDGQEVISKPQTPLAARPRSISESSASSAKEDEK-ESSDEADKNSPRNTAQRGK 899
PP + +P PR + + K + + + + P T +G
Sbjct: 570 PGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGD 629
Query: 900 LG-DG-------KEHTKSSGFGWFSWFRSKPTKNASPAGDEDSSDSPDSEETPRASSPHQ 951
G DG K H G P+ P GD D D E PR
Sbjct: 630 RGFDGLAGLPGEKGHRGDPG----------PSGPPGPPGD-DGERGDDGEVGPRGLPGEP 678
Query: 952 AGLGLSLTPSPESPPLPDVSAFSRGRGGGEG----RGSASSGGAAAGAGVGGLSGPESVS 1007
GL P PP P G+ G +G +G G G GL GP+
Sbjct: 679 GPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGA- 737
Query: 1008 FELCSNPGVLLPPPALKGAVPLYNPSQVPQLPTA 1041
+ PP KG PL P +P +P A
Sbjct: 738 ----------IGPPGEKG--PLGKPG-LPGMPGA 758
Score = 34.3 bits (77), Expect = 0.64
Identities = 71/305 (23%), Positives = 90/305 (29%), Gaps = 63/305 (20%)
Query: 714 GDIGDPHPTRSDISGAGGTTTENTFY--QDFSGCQGYSEAPGYRSALWLTPEQTCLLQPS 771
G IG P P+ +D G G + + + G +G+ PG P
Sbjct: 1186 GPIGQPGPSGAD--GEPGPRGQQGLFGQKGDEGPRGFPGPPG----------------PV 1227
Query: 772 PQQPFPLQPGSYPAGGGAGQTGTPRPFYSVPETHLPGTGSSVAVTEATG--GTVWEEMLQ 829
Q P PG G GQ G P P + PG G G V E+
Sbjct: 1228 GLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEK--- 1284
Query: 830 THLGPGENTVSQETSQPPDGQEVISKPQTPLAARPR--SISESSASSAKEDEKESSDEAD 887
GE + E P +G P P R S A+ + D+
Sbjct: 1285 -----GEPGEAGEPGLPGEG-----GPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGP 1334
Query: 888 KNSPRNTAQRGKLGDGKEHTKSSGFGWFSWFRSKPTKNASPAG-DEDSSDSPDSEETPRA 946
K SP G G P PAG D D D E +
Sbjct: 1335 KGSPGPVGFPGDPG--------------------PPGEPGPAGQDGPPGDKGDDGEPGQT 1374
Query: 947 SSPHQAG-LGLSLTPSPESPPLPDVSAFSRGRGGGEG----RGSASSGGAAAGAGVGGLS 1001
SP G G S P PP P +G G +G G G G G
Sbjct: 1375 GSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKP 1434
Query: 1002 GPESV 1006
GP+ +
Sbjct: 1435 GPDGL 1439
Score = 33.1 bits (74), Expect = 1.4
Identities = 24/80 (30%), Positives = 34/80 (42%), Gaps = 8/80 (10%)
Query: 925 NASPAGDEDSSDSPDSEETPRASSPHQAGLGLSLTPSPESPPLPDVSAFSRGRGGGEG-R 983
N P G + SP A+ P +G+ P P+ PP P A +G G +G +
Sbjct: 1076 NEGPPGPPGPAGSPGERGPAGAAGP----IGIPGRPGPQGPPGP---AGEKGAPGEKGPQ 1128
Query: 984 GSASSGGAAAGAGVGGLSGP 1003
G A G G+ G +GP
Sbjct: 1129 GPAGRDGLQGPVGLPGPAGP 1148
>gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens]
Length = 1192
Score = 46.6 bits (109), Expect = 1e-04
Identities = 78/312 (25%), Positives = 99/312 (31%), Gaps = 53/312 (16%)
Query: 727 SGAGGTTTENTFYQDFSGCQGYSEAPGYRSALWLTPEQTCLLQPSPQQPFPLQPGSYPAG 786
+G GG S + S APG R +LW P P P L P P
Sbjct: 83 AGTGGAEPPALSPAPASPARPVSPAPGRRLSLWAVP-------PGPPLSGGLSPDPKP-- 133
Query: 787 GGAGQTGTPRPFYSVPETHLPGTGSSVAVTEATGGTVWEEMLQTHLGPGENTVSQETSQP 846
G T + RP S P G A GG H G G + + + P
Sbjct: 134 -GGAPTSSRRPLLS-----SPSWGGPEPEGRAGGGIPGSS--SPHPGTGSRRL--KVAPP 183
Query: 847 PDGQEVISKPQTPLAARPRSISESSASSAKEDEKESSDEADKNSPRNTAQRGKL------ 900
P + T A S S E E + + K+S A
Sbjct: 184 PPAPKPCKTVTTSGAKAGGGKGAGSRLSWPESEGKPRVKGSKSSAGTGASVSAAATAAAA 243
Query: 901 -GDGKEHTKSSGFGWFSWFRSKPTKNASPAGDEDSSD--------SPDSEETPRASSPHQ 951
G G + S G G + R K + + D+SD SP P SP
Sbjct: 244 GGGGSTASTSGGVGAGAGARGKLSPRKGKSKTLDNSDLHPGPPAGSPPPLTLPPTPSPAT 303
Query: 952 AGLGLSLTPSPESPPL---PDVSAFSRGRGGG-------------EGRGSASSGGAAAGA 995
A S P +PP+ P RGR GG G + S+GG
Sbjct: 304 AVTAASAQPPGPAPPITLEPPAPGLKRGREGGRASTRDRKMLKFISGIFTKSTGGP---P 360
Query: 996 GVGGLSGPESVS 1007
G G L GP S+S
Sbjct: 361 GSGPLPGPPSLS 372
Score = 38.5 bits (88), Expect = 0.034
Identities = 32/104 (30%), Positives = 45/104 (43%), Gaps = 17/104 (16%)
Query: 938 PDSEETPRAS-SPHQAGLGLSLTPSPESPPLPDVSAFSRGRGGGEGRGSASSGGAAAGAG 996
P+SE PR S AG G S++ +A + GG G +++SGG AGAG
Sbjct: 213 PESEGKPRVKGSKSSAGTGASVS-----------AAATAAAAGGGGSTASTSGGVGAGAG 261
Query: 997 VGGLSGPESVSFELCSNPGVLLPPPALKGAVPLYNPSQVPQLPT 1040
G P + N + PPA G+ P P +P P+
Sbjct: 262 ARGKLSPRKGKSKTLDNSDLHPGPPA--GSPP---PLTLPPTPS 300
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 45.8 bits (107), Expect = 2e-04
Identities = 36/157 (22%), Positives = 66/157 (42%), Gaps = 6/157 (3%)
Query: 836 ENTVSQETSQPPDGQEVISKPQTPLAARPRSISESSASSAKEDEKESSDEADKNSPRNTA 895
+++ S E+S D + + + + S S+SS SS D ESS+ +D ++ +++
Sbjct: 881 DSSDSNESSNSSDSSDSSNSSDSDSSDSSNS-SDSSDSSNSSDSSESSNSSDNSNSSDSS 939
Query: 896 QRGKLGDGKEHTKSSGFGWFSWFRSKPTKNASPAGDEDSSDSPDSEETPRASSPHQAGLG 955
D + + SS S + N+S + D +SSDS DS + +S +
Sbjct: 940 NSSDSSDSSDSSNSSDSS-----NSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDS 994
Query: 956 LSLTPSPESPPLPDVSAFSRGRGGGEGRGSASSGGAA 992
+ S S D S S + S+ S ++
Sbjct: 995 SDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSS 1031
Score = 43.1 bits (100), Expect = 0.001
Identities = 39/176 (22%), Positives = 71/176 (40%), Gaps = 8/176 (4%)
Query: 836 ENTVSQETSQPPDGQEVISKPQTPLAARPRSISESSASSAKEDEKESSDEADKNSPRNTA 895
+++ S +S D + + ++ SESS SS D +SSD +D + +++
Sbjct: 1116 DSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSS 1175
Query: 896 QRGKLGDGKEHTKSSGFGWFSWFRSKPTKNASPAGDEDSSDSPDSEETPRASSPHQAGLG 955
D + + SS S S + ++ + DSSDS DS ++ +S +
Sbjct: 1176 DSSNSSDSSDSSDSSD----SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1231
Query: 956 LSLTPSPESPPLPDVSAFSRGRGGGEGRGSASSGG----AAAGAGVGGLSGPESVS 1007
+ S +S D S S + S S + + +G G +G +S S
Sbjct: 1232 NESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDS 1287
Score = 40.8 bits (94), Expect = 0.007
Identities = 29/125 (23%), Positives = 49/125 (39%), Gaps = 7/125 (5%)
Query: 868 SESSASSAKEDEKESSDEADKNSPRNTAQRGKLGDGKEHTKSSGFGWFSWFRSKPTKNAS 927
S+SS SS+ D SSD +D + N+++ D + S N+S
Sbjct: 672 SDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDS-------SDSSNSNSS 724
Query: 928 PAGDEDSSDSPDSEETPRASSPHQAGLGLSLTPSPESPPLPDVSAFSRGRGGGEGRGSAS 987
+ +SSDS DS + +S + + S +S D S S + S+
Sbjct: 725 DSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSD 784
Query: 988 SGGAA 992
S ++
Sbjct: 785 SNDSS 789
Score = 39.7 bits (91), Expect = 0.015
Identities = 34/158 (21%), Positives = 65/158 (41%), Gaps = 9/158 (5%)
Query: 836 ENTVSQETSQPPDGQEVISKPQTPLAARPRSISESSASSAKEDEKESSDEADKNSPRNTA 895
+++ S +S D + + ++ SESS SS + +SSD +D + +++
Sbjct: 1050 DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSS 1109
Query: 896 QRGKLGDGKEHTKSSGFGWFSWFRSKPTKNASPAGD-EDSSDSPDSEETPRASSPHQAGL 954
D + + SS S + ++S + D +SSDS DS E+ +S +
Sbjct: 1110 DSSDSSDSSDSSNSSD--------SSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSD 1161
Query: 955 GLSLTPSPESPPLPDVSAFSRGRGGGEGRGSASSGGAA 992
+ S +S D S S + S+ S ++
Sbjct: 1162 SSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSS 1199
Score = 38.5 bits (88), Expect = 0.034
Identities = 37/152 (24%), Positives = 59/152 (38%), Gaps = 14/152 (9%)
Query: 840 SQETSQPPDGQEVISKPQTPLAARPRSISESSASSAKEDEKESSDEADKNSPRNTAQRGK 899
S +S D + ++ S+SS SS D +SSD +D + N++
Sbjct: 728 SSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSND 787
Query: 900 LGDGKEHTKSSGFGWFSWFRSKPTKNASPAGDEDSSDSPDSEETPRASSPHQAGLGLSLT 959
+ + + SS S + N+S + D SSDS DS+ + + S + + S
Sbjct: 788 SSNSSDSSDSSN--------SSDSSNSSDSSD--SSDSSDSDSSNSSDSSNSSDSSDSSN 837
Query: 960 PSPESPPLPDVSAFSRGRGGGEGRGSASSGGA 991
S S D S S G S SS +
Sbjct: 838 SSDSS----DSSDSSDGSDSDSSNRSDSSNSS 865
Score = 38.1 bits (87), Expect = 0.044
Identities = 37/167 (22%), Positives = 68/167 (40%), Gaps = 23/167 (13%)
Query: 836 ENTVSQETSQPPDGQEVISKPQTPLAARPRSISESSASSAKEDEKESSDEADKNSPRNTA 895
+++ S ++S D + SK + + S S+S + S+ + +SSD +D + N++
Sbjct: 606 DSSDSSDSSDSSDSSD--SKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSS 663
Query: 896 QRGKLGDGKEHTKSSGFGWFSWFRSKPTKNASPAGDE----------DSSDSPDSEETPR 945
D + + SS S + N+S + D DSSDS DS+ +
Sbjct: 664 NSSDSSDSSDSSDSSS--------SSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDS 715
Query: 946 ASSPHQAGLGLSLTPSPESPPLPDVSAFSRGRGGGEGRGSASSGGAA 992
+ S + S + S S D S S + S+ S ++
Sbjct: 716 SDSSNS---NSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSS 759
Score = 38.1 bits (87), Expect = 0.044
Identities = 25/112 (22%), Positives = 51/112 (45%), Gaps = 11/112 (9%)
Query: 836 ENTVSQETSQPPDGQEVISKPQTPLAARPRSISESSASSAKEDEKESSDEADKNSPRNTA 895
+++ S +S D + + + ++ + S+SS SS D +SS+ +D N N++
Sbjct: 733 DSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSS 792
Query: 896 QRGKLGDGKEHTKSSGFGWFSWFRSKPTKNASPAGDEDSSDSPDSEETPRAS 947
+ + + SS + ++S + D DSS+S DS + +S
Sbjct: 793 DSSDSSNSSDSSNSS-----------DSSDSSDSSDSDSSNSSDSSNSSDSS 833
Score = 37.4 bits (85), Expect = 0.076
Identities = 33/153 (21%), Positives = 61/153 (39%), Gaps = 27/153 (17%)
Query: 840 SQETSQPPDGQEVISKPQTPLAARPRSISESSASSAKEDEKESSDEADKNSPRNTAQRGK 899
S ++S DG + S ++ + + S+SS SS + +SSD +D N N++
Sbjct: 841 SSDSSDSSDGSDSDSSNRSDSS----NSSDSSDSSDSSNSSDSSDSSDSNESSNSSD--- 893
Query: 900 LGDGKEHTKSSGFGWFSWFRSKPTKNASPAGDEDSSDSPDSEETPRASSPHQAGLGLSLT 959
S + N+S + DSS+S DS ++ +S ++ +
Sbjct: 894 --------------------SSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNS 933
Query: 960 PSPESPPLPDVSAFSRGRGGGEGRGSASSGGAA 992
S +S D S S + S+ S ++
Sbjct: 934 NSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSS 966
Score = 33.1 bits (74), Expect = 1.4
Identities = 26/119 (21%), Positives = 45/119 (37%), Gaps = 1/119 (0%)
Query: 870 SSASSAKEDEKESSDEADKNSPRNTAQRGKLGDGKEHTKSSGFGWFSWFRSKPTKNASPA 929
S + A++D+ +S+ + + + G D + G S S + N+S +
Sbjct: 505 SDSKGAEDDDSDSTSDTNNSDSNGNGNNGN-DDNDKSDSGKGKSDSSDSDSSDSSNSSDS 563
Query: 930 GDEDSSDSPDSEETPRASSPHQAGLGLSLTPSPESPPLPDVSAFSRGRGGGEGRGSASS 988
D SDS DS + + S S + S +S D S S + S+ S
Sbjct: 564 SDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDS 622
Score = 33.1 bits (74), Expect = 1.4
Identities = 32/140 (22%), Positives = 59/140 (42%), Gaps = 5/140 (3%)
Query: 861 AARPRSISESSASSAKEDEKESSDEADKNSPRNTAQRGKLGDGKEHTKSSGFGWFSWFRS 920
+ + +S S S SS + +SSD +D +S + + + + SS S
Sbjct: 542 SGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNS 601
Query: 921 KPTKNASPAGDE-DSSDSPDSE----ETPRASSPHQAGLGLSLTPSPESPPLPDVSAFSR 975
+ ++S + D DSSDS DS+ ++ SS + S + S +S D S S
Sbjct: 602 SDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSN 661
Query: 976 GRGGGEGRGSASSGGAAAGA 995
+ S+ S +++ +
Sbjct: 662 SSNSSDSSDSSDSSDSSSSS 681
Score = 30.4 bits (67), Expect = 9.2
Identities = 16/66 (24%), Positives = 30/66 (45%), Gaps = 10/66 (15%)
Query: 878 DEKESSDEADKNSPRNTAQRGKLGDGKEHTKSSGFGWFSWFRSKPTKNASPAGDEDSSDS 937
DE +D+A+ S N++ RG + +K +G G ++ A D+DS +
Sbjct: 469 DESNGNDDANSESDNNSSSRGDASYNSDESKDNGNG----------SDSKGAEDDDSDST 518
Query: 938 PDSEET 943
D+ +
Sbjct: 519 SDTNNS 524
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 44.7 bits (104), Expect = 5e-04
Identities = 67/295 (22%), Positives = 101/295 (34%), Gaps = 46/295 (15%)
Query: 778 LQPGSYPAGGGAGQTGTPRPFYSVPE-THLPGTGSSV-----------AVTEATGGTVWE 825
L GSYP G+ + P P + + PG G + A E G E
Sbjct: 2499 LSLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESE 2558
Query: 826 EMLQTHLGPGENTVSQETS-QPPDGQEVISKP---------QTPLAARPRSISESSASSA 875
+ G ++ S +S +G+E K + AA R+ S +S+SS+
Sbjct: 2559 SSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSS 2618
Query: 876 KEDEKESSDEADKNSPRNTAQRGKLGDGKEHTKSSGFGWFSWFRSKPTKNASPAGDEDSS 935
SS + +S +++ + SS S S + ++S DEDSS
Sbjct: 2619 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSS 2678
Query: 936 DSPDSEETPRASSPHQAGLGLSLTPSPESPPLPDVSAFSRGRGGGEGRGSASSGGAAAGA 995
S D E P ++ A L + ++ G+ R SA S G A
Sbjct: 2679 CSSDDEAAPAPTAGPSAQAALPTKATKQA---------------GKARPSAHSPGKKTPA 2723
Query: 996 GVGGLSGPESVSFELCSNPGVLLPPPALKGAVPLYNPSQVPQLPTATSLNRPNRL 1050
P+ P L P A GA + LPT L + RL
Sbjct: 2724 PQPQAPPPQ---------PTQPLQPKAQAGAKSRPKKREGVHLPTTKELAKRQRL 2769
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 44.7 bits (104), Expect = 5e-04
Identities = 86/370 (23%), Positives = 136/370 (36%), Gaps = 57/370 (15%)
Query: 695 DLEPDWLAQLRRQLEQKVAGDIGDP---HPTRSDISGAGGTTTENTFYQDFSGCQGYSEA 751
+L PD + + Q ++ + D P+R S A ++ + S +
Sbjct: 1385 ELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSS 1444
Query: 752 PGYRSALWLTPEQTCLLQPSP-QQPFPLQPGSYPAGGGAGQTGTPRPFYSVPETHLPGTG 810
PG R TP + L SP + P P G + +P P ++P+T P +
Sbjct: 1445 PGLRDGSG-TPSRHSLSGSSPGMKDIPRTPSR----GRSECDSSPEP-KALPQTPRPRSR 1498
Query: 811 SSVAVTEATGGTVWEEMLQTHLGPGENTVSQETSQPPDGQEVISKPQTPLAARPRSISES 870
S + E+ L P E+S Q+ +++ TPL R RS S
Sbjct: 1499 SPSS----------PELNNKCLTPQRERSGSESSVD---QKTVAR--TPLGQRSRSGSSQ 1543
Query: 871 ------SASSAKEDEKESSDEADKNSPRNTAQRGKLGDGKEHTKSSGFGWFSWFRSKPTK 924
SAS + E +SS ++ + QR + G E S R P +
Sbjct: 1544 ELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKS--------RLSPRR 1595
Query: 925 NASPAGDEDSSDSPDSEETPRASSPHQAGLGLSLTPSPESPPLPDVSAFSRGRGGGEGRG 984
+ S SP+ ++ PRA+ Q+G S P P++P + SR +GRG
Sbjct: 1596 SRS-------GSSPEVKDKPRAAPRAQSGSDSS--PEPKAPAPRALPRRSRSGSSSKGRG 1646
Query: 985 SASSGGAAAGAGVGGLSGPESVSFELCSNPGV-LLPPPALKGAVPLYNPS--QVPQLPTA 1041
+ G ++ S PE + G P P K P S P+L
Sbjct: 1647 PSPEGSSSTE------SSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRK 1700
Query: 1042 TSLNRPNRLA 1051
L+R +R A
Sbjct: 1701 ARLSRRSRSA 1710
Score = 35.8 bits (81), Expect = 0.22
Identities = 39/166 (23%), Positives = 58/166 (34%), Gaps = 28/166 (16%)
Query: 831 HLGPGENTVSQETSQPP------DGQEVISKPQTPLAARPRSISESSASSAKEDEKESSD 884
H GE S QP +E S + ++ S S SS+SS+ SSD
Sbjct: 2503 HSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSD 2562
Query: 885 EADKN-----------------SPRNTAQRGKLGDG-----KEHTKSSGFGWFSWFRSKP 922
+ +P+ + G+ + K + SS S S
Sbjct: 2563 SEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSS 2622
Query: 923 TKNASPAGDEDSSDSPDSEETPRASSPHQAGLGLSLTPSPESPPLP 968
+ ++S + SS S S + +SSP A G P P SP P
Sbjct: 2623 SSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKP 2668
Score = 31.6 bits (70), Expect = 4.1
Identities = 36/196 (18%), Positives = 73/196 (37%), Gaps = 16/196 (8%)
Query: 724 SDISGAGGTTTENTFYQDFSGCQGYSEAPGYRSALWLTPEQTCLLQPSPQQPFPLQ---- 779
S S + +++ ++ S G S + S+L + PE PSP P P +
Sbjct: 2534 SSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPT-PAPKEAVRE 2592
Query: 780 -------PGSYPAGGGAGQTGTPRPFYSVPETHLPGTGSSVAVTEATGGTVWEEMLQTHL 832
P + + + S + + SS + + ++ + +
Sbjct: 2593 GRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPA 2652
Query: 833 GPGENTVSQETS--QPPDGQEVISKPQTPLAAR--PRSISESSASSAKEDEKESSDEADK 888
PG + + S +PP G+ P+ P+ + RS+S S + + S +
Sbjct: 2653 KPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQS 2712
Query: 889 NSPRNTAQRGKLGDGK 904
+S ++RG+ GD +
Sbjct: 2713 SSSERGSRRGQRGDSR 2728
Score = 31.2 bits (69), Expect = 5.4
Identities = 35/199 (17%), Positives = 70/199 (35%), Gaps = 17/199 (8%)
Query: 770 PSPQQPFPLQPGSYPAGGGAGQTGTPRPFYSVPETHLPGTGSSVAVTEATGGTVWEEMLQ 829
P+P P G PA GA Q E + SS + + ++ +
Sbjct: 2497 PAPGVPHS-DVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSS---SSSS 2552
Query: 830 THLGPGENTVSQETSQPPDGQEVISKPQTPLAARPRSISES---SASSAKEDEKESSDEA 886
+ ++ S+ +S P + + + +P A ++ E + AK + SS +
Sbjct: 2553 SSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSS 2612
Query: 887 DKNSPRNTAQRGKLGDGKEHTKSSGFGWFSWFRSKPTKNASPAGDEDSSDSPDSEETPRA 946
+S +++ + SS + ++S + S P + P+
Sbjct: 2613 SSSSSSSSSSSSSSSSSSSSSSSSS----------SSSSSSSSSSSPSPAKPGPQALPKP 2662
Query: 947 SSPHQAGLGLSLTPSPESP 965
+SP + G + SP P
Sbjct: 2663 ASPKKPPPGERRSRSPRKP 2681
>gi|28559039 mediator complex subunit 1 [Homo sapiens]
Length = 1581
Score = 43.9 bits (102), Expect = 8e-04
Identities = 58/241 (24%), Positives = 87/241 (36%), Gaps = 29/241 (12%)
Query: 771 SPQQPF--PLQPGSYPAGGGAGQTGTPRPFYSVP----------ETHLPGTGSSVAVTEA 818
S +PF P G + G AG++ TP + P T + G SS + +
Sbjct: 1026 SSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTS 1085
Query: 819 TGGTVWEEMLQTHLGPGENTVSQETSQPPDGQEVISKPQTPLAARPRSISESSASSAKED 878
+G H ++ S TS + + L++ S+ S SS
Sbjct: 1086 SGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSS---SMYSSQGSSGSSQ 1142
Query: 879 EKESSDEADKNSPRNTAQRGKLGDGKEHTKSSGFGWFSWFRSKPTKNASPAGDEDSSDSP 938
K SS K + G L G TK G KP+ +P+ + + SP
Sbjct: 1143 SKNSSQSGGKPGSSPITKHG-LSSGSSSTKMKPQG-------KPSSLMNPSLSKPNI-SP 1193
Query: 939 DSEETPRASSPHQAGLGLSLTPSPESPPLPDV-SAFSRGRGGGEGRGSASSGGAAAGAGV 997
P S L + P P +PP S S G GG G++SS G + +G+
Sbjct: 1194 SHSRPPGGSDK----LASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGL 1249
Query: 998 G 998
G
Sbjct: 1250 G 1250
Score = 34.7 bits (78), Expect = 0.49
Identities = 29/128 (22%), Positives = 49/128 (38%), Gaps = 17/128 (13%)
Query: 839 VSQETSQPPDGQEVISKPQTPLAARPRSISESSASSAKEDEKESSDEADKNSPRNTAQRG 898
+S S+PP G + ++ P P+ P S S S+ S + + ++++ G
Sbjct: 1191 ISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLG 1250
Query: 899 KLGDGKEHTKSSGFGWFSWFRSKPTKNASPAGDEDSSDSPDSEETPRASSPHQAGLGLSL 958
G + T P+ N+ A SS S S + +SS +Q G
Sbjct: 1251 SSGSLSQKT-------------PPSSNSCTA----SSSSFSSSGSSMSSSQNQHGSSKGK 1293
Query: 959 TPSPESPP 966
+PS P
Sbjct: 1294 SPSRNKKP 1301
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 43.9 bits (102), Expect = 8e-04
Identities = 60/243 (24%), Positives = 90/243 (37%), Gaps = 37/243 (15%)
Query: 833 GPGENT----VSQETSQPPDGQEVISKPQTPLAARPRSISESSASSAKEDEKESSDEADK 888
G GE++ V+ E S P + ++ +P P+ S SSA++ ++ A +
Sbjct: 129 GEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQ 188
Query: 889 NSPRNTAQRGKLGDGKEHTKSSGFGWFSWFRSKPTKNAS---PAGDEDSSDSPDSEETPR 945
T G + G PT +A+ P G +S +P+ + P
Sbjct: 189 APTGVTPAPSSAPPGTPQLPTPG----------PTPSATAVPPQGSPTASQAPNQPQAPT 238
Query: 946 ASSPH-----QAGLGLSLTPSPESPPLPDVSAFSRGRGGGEGRGSASSGGAAAGAGVGGL 1000
A PH L PSP PP P + G G+ SA S G G
Sbjct: 239 APVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGP- 297
Query: 1001 SGPESV-SFELCSNPG----VLLPPPALKGAVPL---------YNPSQVPQLPTATSLNR 1046
GP S+ + L +PG LPP A +G PL + Q+P +A +
Sbjct: 298 PGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQ 357
Query: 1047 PNR 1049
P R
Sbjct: 358 PPR 360
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 43.9 bits (102), Expect = 8e-04
Identities = 60/243 (24%), Positives = 90/243 (37%), Gaps = 37/243 (15%)
Query: 833 GPGENT----VSQETSQPPDGQEVISKPQTPLAARPRSISESSASSAKEDEKESSDEADK 888
G GE++ V+ E S P + ++ +P P+ S SSA++ ++ A +
Sbjct: 683 GEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQ 742
Query: 889 NSPRNTAQRGKLGDGKEHTKSSGFGWFSWFRSKPTKNAS---PAGDEDSSDSPDSEETPR 945
T G + G PT +A+ P G +S +P+ + P
Sbjct: 743 APTGVTPAPSSAPPGTPQLPTPG----------PTPSATAVPPQGSPTASQAPNQPQAPT 792
Query: 946 ASSPH-----QAGLGLSLTPSPESPPLPDVSAFSRGRGGGEGRGSASSGGAAAGAGVGGL 1000
A PH L PSP PP P + G G+ SA S G G
Sbjct: 793 APVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGP- 851
Query: 1001 SGPESV-SFELCSNPG----VLLPPPALKGAVPL---------YNPSQVPQLPTATSLNR 1046
GP S+ + L +PG LPP A +G PL + Q+P +A +
Sbjct: 852 PGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQ 911
Query: 1047 PNR 1049
P R
Sbjct: 912 PPR 914
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 43.9 bits (102), Expect = 8e-04
Identities = 60/243 (24%), Positives = 90/243 (37%), Gaps = 37/243 (15%)
Query: 833 GPGENT----VSQETSQPPDGQEVISKPQTPLAARPRSISESSASSAKEDEKESSDEADK 888
G GE++ V+ E S P + ++ +P P+ S SSA++ ++ A +
Sbjct: 683 GEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQ 742
Query: 889 NSPRNTAQRGKLGDGKEHTKSSGFGWFSWFRSKPTKNAS---PAGDEDSSDSPDSEETPR 945
T G + G PT +A+ P G +S +P+ + P
Sbjct: 743 APTGVTPAPSSAPPGTPQLPTPG----------PTPSATAVPPQGSPTASQAPNQPQAPT 792
Query: 946 ASSPH-----QAGLGLSLTPSPESPPLPDVSAFSRGRGGGEGRGSASSGGAAAGAGVGGL 1000
A PH L PSP PP P + G G+ SA S G G
Sbjct: 793 APVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGP- 851
Query: 1001 SGPESV-SFELCSNPG----VLLPPPALKGAVPL---------YNPSQVPQLPTATSLNR 1046
GP S+ + L +PG LPP A +G PL + Q+P +A +
Sbjct: 852 PGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQ 911
Query: 1047 PNR 1049
P R
Sbjct: 912 PPR 914
>gi|57222568 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 6 [Homo sapiens]
Length = 1093
Score = 43.1 bits (100), Expect = 0.001
Identities = 29/139 (20%), Positives = 57/139 (41%), Gaps = 7/139 (5%)
Query: 836 ENTVSQETSQPPDGQEVISKPQTPLAARPRSISESSASSAKEDEKESSDEADKNSPRNTA 895
E + +P +++ P P A + S S SS+S + +E+S+ + ++ + ++
Sbjct: 246 ERLKQKHKKRPESPPSILTPPVVPTADKVSS-SASSSSHHEASTQETSESSRESKGKKSS 304
Query: 896 QRGKLGDGKEHTKSSGFGWFSWFRSKPTKNASPAGD------EDSSDSPDSEETPRASSP 949
GK+ + G F+ S + ++S +G SPD P+ P
Sbjct: 305 SHSLSHKGKKLSSGKGVSSFTSASSSSSSSSSSSGGPFQPAVSSLQSSPDFSAFPKLEQP 364
Query: 950 HQAGLGLSLTPSPESPPLP 968
+ P+P +PP P
Sbjct: 365 EEDKYSKPTAPAPSAPPSP 383
Score = 32.7 bits (73), Expect = 1.9
Identities = 48/222 (21%), Positives = 73/222 (32%), Gaps = 45/222 (20%)
Query: 834 PGENTVSQETSQPPDGQEVISKPQTPLAARPRS---------ISESSASSAKEDEKESSD 884
P E+ S+ T+ P S P+ P A I S +++ +
Sbjct: 364 PEEDKYSKPTAPAPSAPPSPSAPEPPKADLFEQKVVFSGFGPIMRFSTTTSSSGRARAPS 423
Query: 885 EADKNSPRNTAQRGKLGDGKEHTKSSGFGWFSWFRSKPTKNASPAGDEDSSDSPDSEETP 944
D SP T G K P +A+P +++ ++ E+
Sbjct: 424 PGDYKSPHVTGSGASAGTHKR---------------MPALSATPVPADETPETGLKEKKH 468
Query: 945 RASSPHQAGLGLSL-------TPSPESPPLPDVSAFSRGRGGGEGRGSASSGGAAAGAGV 997
+AS + G G T P +P LP G S SGG+ +G+
Sbjct: 469 KASKRSRHGPGRPKGSRNKEGTGGPAAPSLPSAQL----AGFTATAASPFSGGSLVSSGL 524
Query: 998 GGLS----GPESVSFELCSNPGVLLPPPALKGAVPLYNPSQV 1035
GGLS GP S P + L P L + N +
Sbjct: 525 GGLSSRTFGPSG------SLPSLSLESPLLGAGIYTSNKDPI 560
Score = 30.4 bits (67), Expect = 9.2
Identities = 15/34 (44%), Positives = 18/34 (52%)
Query: 974 SRGRGGGEGRGSASSGGAAAGAGVGGLSGPESVS 1007
SR GG G G+ GG+ G G G +SG S S
Sbjct: 187 SRHSSGGGGGGAGGGGGSMGGGGSGFISGRRSRS 220
>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
Length = 1312
Score = 42.7 bits (99), Expect = 0.002
Identities = 67/283 (23%), Positives = 98/283 (34%), Gaps = 51/283 (18%)
Query: 780 PGSYPAGGGAGQTGTPRPFYSVPETHLPGTGSSVAVTEATGGTVWEEMLQTHLGPGENTV 839
P PA A + +P P S P P + A +++ T
Sbjct: 184 PAPPPAPSSASSSPSPSPSSSSPSPPPPPPPPAPPAPPAPRFDIYDPFHPT--------- 234
Query: 840 SQETSQPPDGQEVISKPQTPLAARPRSISESSASSAKEDEKESSDEADKNSPRNTAQRGK 899
E PP E P P + P S + + + +E+E+E +E +++
Sbjct: 235 -DEAYSPPPAPEQKYDPFEPTGSNPSSSAGTPSPEEEEEEEEEEEEEEED---------- 283
Query: 900 LGDGKEHTKSSGFGWFSWFRSKPTKNASPAGDEDSSDSPDSEETPRASSPHQAGLGLSLT 959
+ +E S S + AG D D+ S++ P SP T
Sbjct: 284 --EEEEEGLSQSISRIS---------ETLAGIYD--DNSLSQDFPGDESPRPDAQPTQPT 330
Query: 960 PSPESPPLPDVSAFSRGRGGGEGRGSASSGGAAAGAGVGGLSGPESVSFELCSNPGVLLP 1019
P+P +PP D + R G R G A A G VS E+ + G LP
Sbjct: 331 PAPGTPPQVDST-----RADGAMRRRVFVVGTEAEACREG-----KVSVEVVTAGGAALP 380
Query: 1020 PPALKGA------VPLYNPSQVPQLPTATSLNRPNRLAQRRYP 1056
PP L + P + P+L A SL RP A R P
Sbjct: 381 PPLLPPGDSEIEEGEIVQPEEEPRL--ALSLFRPGGRAARPTP 421
>gi|4885407 hyperpolarization activated cyclic nucleotide-gated
potassium channel 4 [Homo sapiens]
Length = 1203
Score = 42.4 bits (98), Expect = 0.002
Identities = 74/311 (23%), Positives = 96/311 (30%), Gaps = 62/311 (19%)
Query: 770 PSPQQPFPLQPGSYPAGGGAGQTGTPRPFYSVPETHLPGTGSSVAVTEATGGTVW--EEM 827
P+ P S P G G P P V T + G G +A GG++ +
Sbjct: 868 PAGLSPLLPSSSSSPPPGACGSPSAPTPSAGVAATTIAGFGH---FHKALGGSLSSSDSP 924
Query: 828 LQTHLGPGENT--VSQETSQPPDGQEVISKPQTPLAARPRSISESSASSAKEDEKESSDE 885
L T L PG + +Q + PP + + P+ L P S S SS+
Sbjct: 925 LLTPLQPGARSPQAAQPSPAPPGARGGLGLPEHFLPPPPSSRSPSSSPGQLGQPPGELSL 984
Query: 886 ADKNSPRNTAQRGKLGDGKEHTKSSGFGWFSWFRSKPTKNASPAGDEDSSDSPDSEETPR 945
P +T + + G S P SP G PR
Sbjct: 985 GLATGPLSTPETPPRQPEPPSLVAGASGGASPVGFTPRGGLSPPGHSPGPPRTFPSAPPR 1044
Query: 946 ASSPHQAGLGLSLTPSPESPPLPDV----------------------------------- 970
AS H G L P SPP P V
Sbjct: 1045 ASGSH----GSLLLPPASSPPPPQVPQRRGTPPLTPGRLTQDLKLISASQPALPQDGAQT 1100
Query: 971 ----SAFSRG----------RGGGEGRGSASSGG-AAAGAGVGGLSGPESVSFELCSNPG 1015
S S G R GG GS SSGG G G + G + V+ ++ G
Sbjct: 1101 LRRASPHSSGESMAAFPLFPRAGGGSGGSGSSGGLGPPGRPYGAIPG-QHVTLPRKTSSG 1159
Query: 1016 VLLPPPALKGA 1026
L PP +L GA
Sbjct: 1160 SLPPPLSLFGA 1170
Score = 31.6 bits (70), Expect = 4.1
Identities = 27/94 (28%), Positives = 36/94 (38%)
Query: 927 SPAGDEDSSDSPDSEETPRASSPHQAGLGLSLTPSPESPPLPDVSAFSRGRGGGEGRGSA 986
S G + SP +TP +SS H L P+ SP LP S+ G
Sbjct: 835 SALGSASPASSPSQVDTPSSSSFHIQQLAGFSAPAGLSPLLPSSSSSPPPGACGSPSAPT 894
Query: 987 SSGGAAAGAGVGGLSGPESVSFELCSNPGVLLPP 1020
S G AA G +++ L S+ LL P
Sbjct: 895 PSAGVAATTIAGFGHFHKALGGSLSSSDSPLLTP 928
>gi|30181233 leucine-rich repeats and calponin homology (CH) domain
containing 4 [Homo sapiens]
Length = 683
Score = 42.4 bits (98), Expect = 0.002
Identities = 47/198 (23%), Positives = 70/198 (35%), Gaps = 32/198 (16%)
Query: 860 LAARPRSISESSASSAKEDEKESSDEADKNSPRNTAQRGKLGDGKEHTKSSGFGWFSWFR 919
LA PR E + + + D D + P +RG + + + S G G R
Sbjct: 331 LAREPRGPRERKEDGSADGDPVQIDFIDSHVPGEDEERGTVEEQRPPELSPGAG--DRER 388
Query: 920 SKPTKNASPAGDEDSSDSPDS----EETPRASSPHQAGLGLSLTPSPESPPLPDV----- 970
+ ++ PAG+E PD+ +E R G S P L V
Sbjct: 389 APSSRREEPAGEERRR--PDTLQLWQERERRQQQQSGAWGAPRKDSLLKPGLRAVVGGAA 446
Query: 971 SAFSRGRGGGEGRGSASSGGAAAGAGVGGLSGPESVSFELCSNPGVLLPPPALKGAVPLY 1030
+ ++ G + SAS GAAAG G P PA + +P+
Sbjct: 447 AVSTQAMHNGSPKSSASQAGAAAGQGAPA-------------------PAPASQEPLPIA 487
Query: 1031 NPSQVPQLPTATSLNRPN 1048
P+ P S+ RPN
Sbjct: 488 GPATAPAPRPLGSIQRPN 505
>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
[Homo sapiens]
Length = 1412
Score = 41.6 bits (96), Expect = 0.004
Identities = 55/192 (28%), Positives = 73/192 (38%), Gaps = 43/192 (22%)
Query: 803 ETHLPGTGSSVAVTEATGGTVWEEMLQTHLGPGENTVSQETSQPPDGQEVISKPQTPLAA 862
ET G + ATG TV +L S T+ + +E S P AA
Sbjct: 128 ETEKAGKTGNSMPHPATGKTV-ANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAA 186
Query: 863 RPRSISESSASSAKEDEKESSDEAD-------------------KNSP---RNTAQRGKL 900
+P +S A S+ ED SSDE D K +P A GK
Sbjct: 187 KPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAPPGKA 246
Query: 901 GDGKEHTKSSGFGWFSWFRSKPTKNASPAGDEDSSDSPDSEETPRASSPHQA-------G 953
G TK+ KP ++ S + E+SSDS EETP A + QA
Sbjct: 247 GAVASQTKA----------GKPEED-SESSSEESSDS--EEETPAAKALLQAKASGKTSQ 293
Query: 954 LGLSLTPSPESP 965
+G + P+ ESP
Sbjct: 294 VGAASAPAKESP 305
Score = 40.4 bits (93), Expect = 0.009
Identities = 46/166 (27%), Positives = 68/166 (40%), Gaps = 25/166 (15%)
Query: 856 PQTPLAARPRSISESSASSAKEDEKESSDEADKNSPRNTA--QRGKLGD----------G 903
P TP A + +S +SS +ESSD +D P A Q LG+
Sbjct: 454 PATPSAQVGKWEEDSESSS-----EESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPA 508
Query: 904 KEHTKSSGFGWFSWFRSKPTKNASPAGDEDSSDSPDSEETPRASSPHQAGLGLSLTPSPE 963
K + +G KP N+ + E+SSDS DSEE P A + QA L + +
Sbjct: 509 KGPPQKAGPVAVQVKAEKPMDNSESS--EESSDSADSEEAPAAMTAAQAKPALKIPQTKA 566
Query: 964 SPPLPDVSAFSR------GRGGGEGRGSASSGGAAAGAGVGGLSGP 1003
P + +A ++ G G+A+S ++ A GG P
Sbjct: 567 CPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRP 612
Score = 34.7 bits (78), Expect = 0.49
Identities = 27/100 (27%), Positives = 44/100 (44%), Gaps = 2/100 (2%)
Query: 172 NSETHFQSNSRNPCKDSPASNSGQEWPGELFPGSLLAEAQKNKPSLASESNLLQQRESGL 231
+ +TH + P K+SP + PG+ P + A Q + S + ES+ + + +
Sbjct: 813 SGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAV 872
Query: 232 SSSSYELSQYIRDAPERDDPPASAAWSPVQADVSSAGPKA 271
+S+ I P R PA A +P QA +S KA
Sbjct: 873 TSAQVIKPPLIFVDPNRS--PAGPAATPAQAQAASTPRKA 910
Score = 33.1 bits (74), Expect = 1.4
Identities = 30/111 (27%), Positives = 40/111 (36%), Gaps = 18/111 (16%)
Query: 184 PCKDSPASNSGQEWPGELFPGSLLAEAQKNKPSLASESNLLQQRESGLSSSSYELSQYIR 243
P K+SP + PG+ P A+A K + S SS E S
Sbjct: 300 PAKESPRKGAAPAPPGKTGPAVAKAQAGKREED---------------SQSSSEESDSEE 344
Query: 244 DAPERDDPPASAAWSPVQADVSSAGPKAPMKFYIPHVPVSFGPGGQLVHVG 294
+AP + P A P S+ ++P K P P GP V VG
Sbjct: 345 EAPAQAKPSGKA---PQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVG 392
Score = 32.0 bits (71), Expect = 3.2
Identities = 61/307 (19%), Positives = 109/307 (35%), Gaps = 47/307 (15%)
Query: 712 VAGDIGDPHPTRSDISGAGGTTTENTFYQDFSGCQGYSEAPGYRSA---------LWLTP 762
VA + P +S A T T + G + PG SA +
Sbjct: 148 VANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSS 207
Query: 763 EQTCLLQPSPQQPFPLQPGSYPAGGGAGQTGTPRP------FYSVPETHLPGTGSSVAVT 816
++T + + ++ ++ S PA G G+ TP P S + P S +
Sbjct: 208 DETDVEVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSE 267
Query: 817 EATGGT----VWEEMLQTHLGPGENTVSQETSQPPDGQEVISKPQTPLAARPRSISESSA 872
E++ + +LQ + V ++ + + P P P +++++ A
Sbjct: 268 ESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGP-AVAKAQA 326
Query: 873 SSAKEDEKESSDEAD--KNSPRNTAQRGKLGDGKEHTKSSGFGWFSWFRSKPTKNASPA- 929
+ED + SS+E+D + +P GK + + + + P K A+PA
Sbjct: 327 GKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPA--------KESPRKGAAPAP 378
Query: 930 ---------------GDEDS-SDSPDSEETPRASSPHQAGLGLSLTPSPESPPLPDVSAF 973
+EDS S S +S+ A + A L SP+ P +
Sbjct: 379 PRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMG 438
Query: 974 SRGRGGG 980
G+G G
Sbjct: 439 PLGKGAG 445
>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b
[Homo sapiens]
Length = 1411
Score = 41.6 bits (96), Expect = 0.004
Identities = 55/192 (28%), Positives = 73/192 (38%), Gaps = 43/192 (22%)
Query: 803 ETHLPGTGSSVAVTEATGGTVWEEMLQTHLGPGENTVSQETSQPPDGQEVISKPQTPLAA 862
ET G + ATG TV +L S T+ + +E S P AA
Sbjct: 128 ETEKAGKTGNSMPHPATGKTV-ANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAA 186
Query: 863 RPRSISESSASSAKEDEKESSDEAD-------------------KNSP---RNTAQRGKL 900
+P +S A S+ ED SSDE D K +P A GK
Sbjct: 187 KPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAPPGKA 246
Query: 901 GDGKEHTKSSGFGWFSWFRSKPTKNASPAGDEDSSDSPDSEETPRASSPHQA-------G 953
G TK+ KP ++ S + E+SSDS EETP A + QA
Sbjct: 247 GAVASQTKA----------GKPEED-SESSSEESSDS--EEETPAAKALLQAKASGKTSQ 293
Query: 954 LGLSLTPSPESP 965
+G + P+ ESP
Sbjct: 294 VGAASAPAKESP 305
Score = 40.4 bits (93), Expect = 0.009
Identities = 46/166 (27%), Positives = 68/166 (40%), Gaps = 25/166 (15%)
Query: 856 PQTPLAARPRSISESSASSAKEDEKESSDEADKNSPRNTA--QRGKLGD----------G 903
P TP A + +S +SS +ESSD +D P A Q LG+
Sbjct: 454 PATPSAQVGKWEEDSESSS-----EESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPA 508
Query: 904 KEHTKSSGFGWFSWFRSKPTKNASPAGDEDSSDSPDSEETPRASSPHQAGLGLSLTPSPE 963
K + +G KP N+ + E+SSDS DSEE P A + QA L + +
Sbjct: 509 KGPPQKAGPVAVQVKAEKPMDNSESS--EESSDSADSEEAPAAMTAAQAKPALKIPQTKA 566
Query: 964 SPPLPDVSAFSR------GRGGGEGRGSASSGGAAAGAGVGGLSGP 1003
P + +A ++ G G+A+S ++ A GG P
Sbjct: 567 CPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRP 612
Score = 34.7 bits (78), Expect = 0.49
Identities = 27/100 (27%), Positives = 44/100 (44%), Gaps = 2/100 (2%)
Query: 172 NSETHFQSNSRNPCKDSPASNSGQEWPGELFPGSLLAEAQKNKPSLASESNLLQQRESGL 231
+ +TH + P K+SP + PG+ P + A Q + S + ES+ + + +
Sbjct: 813 SGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAV 872
Query: 232 SSSSYELSQYIRDAPERDDPPASAAWSPVQADVSSAGPKA 271
+S+ I P R PA A +P QA +S KA
Sbjct: 873 TSAQVIKPPLIFVDPNRS--PAGPAATPAQAQAASTPRKA 910
Score = 33.1 bits (74), Expect = 1.4
Identities = 30/111 (27%), Positives = 40/111 (36%), Gaps = 18/111 (16%)
Query: 184 PCKDSPASNSGQEWPGELFPGSLLAEAQKNKPSLASESNLLQQRESGLSSSSYELSQYIR 243
P K+SP + PG+ P A+A K + S SS E S
Sbjct: 300 PAKESPRKGAAPAPPGKTGPAVAKAQAGKREED---------------SQSSSEESDSEE 344
Query: 244 DAPERDDPPASAAWSPVQADVSSAGPKAPMKFYIPHVPVSFGPGGQLVHVG 294
+AP + P A P S+ ++P K P P GP V VG
Sbjct: 345 EAPAQAKPSGKA---PQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVG 392
Score = 32.0 bits (71), Expect = 3.2
Identities = 61/307 (19%), Positives = 109/307 (35%), Gaps = 47/307 (15%)
Query: 712 VAGDIGDPHPTRSDISGAGGTTTENTFYQDFSGCQGYSEAPGYRSA---------LWLTP 762
VA + P +S A T T + G + PG SA +
Sbjct: 148 VANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSS 207
Query: 763 EQTCLLQPSPQQPFPLQPGSYPAGGGAGQTGTPRP------FYSVPETHLPGTGSSVAVT 816
++T + + ++ ++ S PA G G+ TP P S + P S +
Sbjct: 208 DETDVEVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSE 267
Query: 817 EATGGT----VWEEMLQTHLGPGENTVSQETSQPPDGQEVISKPQTPLAARPRSISESSA 872
E++ + +LQ + V ++ + + P P P +++++ A
Sbjct: 268 ESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGP-AVAKAQA 326
Query: 873 SSAKEDEKESSDEAD--KNSPRNTAQRGKLGDGKEHTKSSGFGWFSWFRSKPTKNASPA- 929
+ED + SS+E+D + +P GK + + + + P K A+PA
Sbjct: 327 GKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPA--------KESPRKGAAPAP 378
Query: 930 ---------------GDEDS-SDSPDSEETPRASSPHQAGLGLSLTPSPESPPLPDVSAF 973
+EDS S S +S+ A + A L SP+ P +
Sbjct: 379 PRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMG 438
Query: 974 SRGRGGG 980
G+G G
Sbjct: 439 PLGKGAG 445
Score = 31.6 bits (70), Expect = 4.1
Identities = 19/72 (26%), Positives = 26/72 (36%)
Query: 838 TVSQETSQPPDGQEVISKPQTPLAARPRSISESSASSAKEDEKESSDEADKNSPRNTAQR 897
T Q TS G + KP+ P + ESS S + S E D P+
Sbjct: 1033 TSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSA 1092
Query: 898 GKLGDGKEHTKS 909
LG T++
Sbjct: 1093 HTLGPTPSRTET 1104
>gi|57864582 hornerin [Homo sapiens]
Length = 2850
Score = 41.2 bits (95), Expect = 0.005
Identities = 62/235 (26%), Positives = 90/235 (38%), Gaps = 25/235 (10%)
Query: 781 GSYPAGGGAG--QTGTPRPFYSVPETH--LPGTGSSVAVTEATGG---TVWEEMLQTHLG 833
G + +G G G Q G+ +S H G SS +++ G + + +H
Sbjct: 818 GQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHA 877
Query: 834 PGENTVSQETSQPPD-GQEVISKPQTPLAARPRSISESSASSAKEDEK--ESSDEADKNS 890
G + Q P GQ Q+P R S S S+SS + +SS K+S
Sbjct: 878 SGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSS 937
Query: 891 PRNTAQRGKLGDGKEHTKS-SGFGWFSWFRSKPTKNASPAGDEDSSDSPDSEETPRASSP 949
++ + G G H+ S G S S+ ++ S +G S S R S
Sbjct: 938 SGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGS--RQSLG 995
Query: 950 H-QAGLGLSLTPSPESPPLPDVSAFSRGRGGGEGRGSASSGGAAAGAGVGGLSGP 1003
H Q G G +PSP SRGR G S+S G +G+G GP
Sbjct: 996 HGQHGSGSGQSPSP-----------SRGRHGSGSGQSSSYGPYRSGSGWSSSRGP 1039
Score = 35.0 bits (79), Expect = 0.37
Identities = 40/153 (26%), Positives = 63/153 (41%), Gaps = 7/153 (4%)
Query: 857 QTPLAARPRSISESSASSAKEDEKESSDEADKNSPRNTAQRGKLGDGKEHTKS---SGFG 913
Q+P +R R S S SS+ S + P + G G + ++S SG+G
Sbjct: 539 QSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYG 598
Query: 914 WF---SWFRSKPTKNASPAGDEDSSDSPDSEETPRASSPHQAGLGLSLTPSPESPPLPDV 970
S S ++ S +G + SS + ++SS Q G G S +
Sbjct: 599 QHGSSSGHSSTHGQHGSTSG-QSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSG 657
Query: 971 SAFSRGRGGGEGRGSASSGGAAAGAGVGGLSGP 1003
+ SRGR G + S+S G +G+G +GP
Sbjct: 658 QSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGP 690
Score = 33.1 bits (74), Expect = 1.4
Identities = 43/161 (26%), Positives = 61/161 (37%), Gaps = 16/161 (9%)
Query: 846 PPDGQEVISKPQTPLAARPRSISESSASSAKEDE---KESSDEADKNSPRNTAQRGKLGD 902
P GQ Q+P R S S S+SS + + S ++S ++ + G
Sbjct: 2066 PGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGS 2125
Query: 903 GKEHTKSSGFGWFSWFRSKPTKNASPAGDEDSSDSPDSEETPRASSPHQAGLGLSLTPSP 962
G H SSG+G RS + G S S + + S +G G + S
Sbjct: 2126 GSGH--SSGYGQHG-SRSGQSSRGERHGSSSGSSSRYGQHG--SGSRQSSGHGRQGSGSG 2180
Query: 963 ESPPLPDVSAFSRGRGGGEGRGSASSGGAAAGAGVGGLSGP 1003
SP SRGR G S+S G +G+G GP
Sbjct: 2181 HSP--------SRGRHGSGSGHSSSHGQHGSGSGRSSSRGP 2213
Score = 32.7 bits (73), Expect = 1.9
Identities = 37/135 (27%), Positives = 49/135 (36%), Gaps = 23/135 (17%)
Query: 868 SESSASSAKEDEKESSDEADKNSPRNTAQRGKLGDGKEHTKSSGFGWFSWFRSKPTKNAS 927
S S +S+ SS ++ +A R G G +H+ SG S
Sbjct: 379 STSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRG-QHSSGSG--------------QS 423
Query: 928 PAGDEDSSDSPDSEETPRASSPHQAGLGLSLTPSPESPPLPDVSAFSRGRGGGEGRGSAS 987
P + S S S +S H G G S + S P S +S G G E S
Sbjct: 424 PGHGQRGSGSGQSP----SSGQHGTGFGRSSS----SGPYVSGSGYSSGFGHHESSSEHS 475
Query: 988 SGGAAAGAGVGGLSG 1002
SG G+G G SG
Sbjct: 476 SGYTQHGSGSGHSSG 490
Score = 32.7 bits (73), Expect = 1.9
Identities = 43/163 (26%), Positives = 63/163 (38%), Gaps = 20/163 (12%)
Query: 846 PPDGQEVISKPQTPLAARPRSISESSASSAKEDE---KESSDEADKNSPRNTAQRGKLGD 902
P GQ Q+P R S S S+SS + + S ++S ++ + G
Sbjct: 1596 PGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGS 1655
Query: 903 GKEHTKSSGFGWFSWFRSKPTKNASPAGDEDSSDSPDSEETPR--ASSPHQAGLGLSLTP 960
G H SSG+G + S G+ S S S + + S +G G +
Sbjct: 1656 GSGH--SSGYG-----QHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSG 1708
Query: 961 SPESPPLPDVSAFSRGRGGGEGRGSASSGGAAAGAGVGGLSGP 1003
S +SP SRGR G S+S G +G+G GP
Sbjct: 1709 SGQSP--------SRGRHGSGLGHSSSHGQHGSGSGRSSSRGP 1743
Score = 32.7 bits (73), Expect = 1.9
Identities = 43/161 (26%), Positives = 62/161 (38%), Gaps = 16/161 (9%)
Query: 846 PPDGQEVISKPQTPLAARPRSISESSASSAKEDE---KESSDEADKNSPRNTAQRGKLGD 902
P GQ Q+P R S S S+SS + + S ++S ++ + G
Sbjct: 2536 PGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGS 2595
Query: 903 GKEHTKSSGFGWFSWFRSKPTKNASPAGDEDSSDSPDSEETPRASSPHQAGLGLSLTPSP 962
G H SSG+G RS + G S S + + S +G G + S
Sbjct: 2596 GSGH--SSGYGQHG-SRSGQSSRGERHGSSSGSSSHYGQHG--SGSRQSSGHGRQGSGSG 2650
Query: 963 ESPPLPDVSAFSRGRGGGEGRGSASSGGAAAGAGVGGLSGP 1003
+SP SRGR G S+S G +G+G GP
Sbjct: 2651 QSP--------SRGRHGSGLGHSSSHGQHGSGSGRSSSRGP 2683
Score = 32.0 bits (71), Expect = 3.2
Identities = 46/173 (26%), Positives = 66/173 (38%), Gaps = 22/173 (12%)
Query: 849 GQEVISKPQTPLAARPRSISESSASSAKEDEKESSDEADKNSPRNTAQRGKLGDGKEHTK 908
GQ Q+P +R R S S SS+ + S + P + G G ++
Sbjct: 997 GQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESR 1056
Query: 909 ---SSGFGWF---SWFRSKPTKNASPAGDED-------SSDSPDSEETPRASSPHQAGLG 955
SSG+G S S ++ S +G SS S + S +G G
Sbjct: 1057 SGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYG 1116
Query: 956 LSLTPSPESPPLPDVSAFSR-----GR-GGGEGRGSASSGGAAAGAGVGGLSG 1002
+ S +SP + SR GR G G GR S+S G+G+G SG
Sbjct: 1117 RQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSS---GQHGSGLGESSG 1166
Score = 32.0 bits (71), Expect = 3.2
Identities = 43/161 (26%), Positives = 61/161 (37%), Gaps = 16/161 (9%)
Query: 846 PPDGQEVISKPQTPLAARPRSISESSASSAKEDE---KESSDEADKNSPRNTAQRGKLGD 902
P GQ Q+P R S S S+SS + + S ++S ++ + G
Sbjct: 1126 PGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGS 1185
Query: 903 GKEHTKSSGFGWFSWFRSKPTKNASPAGDEDSSDSPDSEETPRASSPHQAGLGLSLTPSP 962
G H SSG+G RS + G S S + + S +G G + S
Sbjct: 1186 GSGH--SSGYGQHG-SRSGQSSRGERHGSSSGSSSHYGQHG--SGSRQSSGHGRQGSGSG 1240
Query: 963 ESPPLPDVSAFSRGRGGGEGRGSASSGGAAAGAGVGGLSGP 1003
SP SRGR G S+S G +G+G GP
Sbjct: 1241 HSP--------SRGRHGSGLGHSSSHGQHGSGSGRSSSRGP 1273
>gi|55769546 PAK1 interacting protein 1 [Homo sapiens]
Length = 392
Score = 41.2 bits (95), Expect = 0.005
Identities = 20/57 (35%), Positives = 31/57 (54%)
Query: 855 KPQTPLAARPRSISESSASSAKEDEKESSDEADKNSPRNTAQRGKLGDGKEHTKSSG 911
K P AA P +S+ + K++ ++ + +K S NT +RG GD K+ TK SG
Sbjct: 310 KESLPPAAEPSPVSKEQSKIGKKEPGDTVHKEEKRSKPNTKKRGLTGDSKKATKESG 366
>gi|7657387 CCR4-NOT transcription complex, subunit 3 [Homo sapiens]
Length = 753
Score = 41.2 bits (95), Expect = 0.005
Identities = 44/179 (24%), Positives = 70/179 (39%), Gaps = 18/179 (10%)
Query: 854 SKPQTPLAARPRSISESSASSAK-EDEKESSDEADKNSPRNTAQRG-KLGDGKEHTKSSG 911
S P + ++ P S ++ ++ ED+K+ D ++ A+ G K +H +S
Sbjct: 259 STPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQSPAKNGSKPVHSNQHPQSPA 318
Query: 912 FG---------WFSWFRSKPTKNASPA-GDEDSSDSPDSEETPRASSPHQAGLGLSLTPS 961
S + P N PA S+ P + P +S A ++ P
Sbjct: 319 VPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPKASPAPSHNSGTPAPYAQAVAPP 378
Query: 962 PESPPL------PDVSAFSRGRGGGEGRGSASSGGAAAGAGVGGLSGPESVSFELCSNP 1014
S P P V G GG G GS+SS ++AG G G +G S S + +P
Sbjct: 379 APSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGGAGKQNGATSYSSVVADSP 437
Score = 32.0 bits (71), Expect = 3.2
Identities = 28/123 (22%), Positives = 49/123 (39%), Gaps = 25/123 (20%)
Query: 32 HHRPVPHSWHNGERFHQWQDNRGSPQPQQEPRADHQQQPHYASRPGDWHQPVSG-----V 86
HH P P + ER Q+ P P H Q P S +++Q +S +
Sbjct: 623 HHMPHPS---DSERIRQYLPRNPCPTPPY-----HHQMPPPHSDTVEFYQRLSTETLFFI 674
Query: 87 DYYEGGYRNQLYSRPGYENS-----------YQSYQSP-TMREEYAYGSYYYHGHPQWLQ 134
YY G + Q + + +Q ++ P T+ +E+ G+Y Y + +W Q
Sbjct: 675 FYYLEGTKAQYLAAKALKKQSWRFHTKYMMWFQRHEEPKTITDEFEQGTYIYFDYEKWGQ 734
Query: 135 EER 137
++
Sbjct: 735 RKK 737
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 40.4 bits (93), Expect = 0.009
Identities = 46/166 (27%), Positives = 68/166 (40%), Gaps = 25/166 (15%)
Query: 856 PQTPLAARPRSISESSASSAKEDEKESSDEADKNSPRNTA--QRGKLGD----------G 903
P TP A + +S +SS +ESSD +D P A Q LG+
Sbjct: 531 PATPSAQVGKWEEDSESSS-----EESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPA 585
Query: 904 KEHTKSSGFGWFSWFRSKPTKNASPAGDEDSSDSPDSEETPRASSPHQAGLGLSLTPSPE 963
K + +G KP N+ + E+SSDS DSEE P A + QA L + +
Sbjct: 586 KGPPQKAGPVAVQVKAEKPMDNSESS--EESSDSADSEEAPAAMTAAQAKPALKIPQTKA 643
Query: 964 SPPLPDVSAFSR------GRGGGEGRGSASSGGAAAGAGVGGLSGP 1003
P + +A ++ G G+A+S ++ A GG P
Sbjct: 644 CPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRP 689
Score = 39.7 bits (91), Expect = 0.015
Identities = 60/226 (26%), Positives = 77/226 (34%), Gaps = 35/226 (15%)
Query: 803 ETHLPGTGSSVAVTEATGGTVWEEMLQTHLGPGENTVSQETSQPPDGQEVISKPQTPLAA 862
ET G + ATG TV +L S T+ + +E S P AA
Sbjct: 128 ETEKAGKTGNSMPHPATGKTV-ANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAA 186
Query: 863 RPRSISESSASSAKEDEKESSDEAD-------------------KNSPRNTA--QRGKLG 901
+P +S A S+ ED SSDE D K SP A GK+G
Sbjct: 187 KPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVG 246
Query: 902 DGKEHTKSSGFGWFSWFRSKPTKNASPAGDEDSSDSPDSEETPRASSPHQAGLGLSLTPS 961
D K P K A +E S SEE + AG + S
Sbjct: 247 DVTPQVKGGAL--------PPAKRAKKPEEESES----SEEGSESEEEAPAGTRSQVKAS 294
Query: 962 PESPPLPDVSAFSRGRGGGEGRGSASSGGAAAGAGVGGLSGPESVS 1007
+ + SA ++G G+G A G A A A PE S
Sbjct: 295 EKILQVRAASAPAKGT-PGKGATPAPPGKAGAVASQTKAGKPEEDS 339
Score = 34.7 bits (78), Expect = 0.49
Identities = 27/100 (27%), Positives = 44/100 (44%), Gaps = 2/100 (2%)
Query: 172 NSETHFQSNSRNPCKDSPASNSGQEWPGELFPGSLLAEAQKNKPSLASESNLLQQRESGL 231
+ +TH + P K+SP + PG+ P + A Q + S + ES+ + + +
Sbjct: 890 SGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAV 949
Query: 232 SSSSYELSQYIRDAPERDDPPASAAWSPVQADVSSAGPKA 271
+S+ I P R PA A +P QA +S KA
Sbjct: 950 TSAQVIKPPLIFVDPNRS--PAGPAATPAQAQAASTPRKA 987
Score = 33.1 bits (74), Expect = 1.4
Identities = 30/111 (27%), Positives = 40/111 (36%), Gaps = 18/111 (16%)
Query: 184 PCKDSPASNSGQEWPGELFPGSLLAEAQKNKPSLASESNLLQQRESGLSSSSYELSQYIR 243
P K+SP + PG+ P A+A K + S SS E S
Sbjct: 377 PAKESPRKGAAPAPPGKTGPAVAKAQAGKREED---------------SQSSSEESDSEE 421
Query: 244 DAPERDDPPASAAWSPVQADVSSAGPKAPMKFYIPHVPVSFGPGGQLVHVG 294
+AP + P A P S+ ++P K P P GP V VG
Sbjct: 422 EAPAQAKPSGKA---PQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVG 469
Score = 31.6 bits (70), Expect = 4.1
Identities = 48/232 (20%), Positives = 85/232 (36%), Gaps = 38/232 (16%)
Query: 778 LQPGSYPAGGGAGQTGTPRP------FYSVPETHLPGTGSSVAVTEATGGT----VWEEM 827
++ S PA G G+ TP P S + P S + E++ + +
Sbjct: 300 VRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKAL 359
Query: 828 LQTHLGPGENTVSQETSQPPDGQEVISKPQTPLAARPRSISESSASSAKEDEKESSDEAD 887
LQ + V ++ + + P P P +++++ A +ED + SS+E+D
Sbjct: 360 LQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGP-AVAKAQAGKREEDSQSSSEESD 418
Query: 888 --KNSPRNTAQRGKLGDGKEHTKSSGFGWFSWFRSKPTKNASPA---------------- 929
+ +P GK + + + + P K A+PA
Sbjct: 419 SEEEAPAQAKPSGKAPQVRAASAPA--------KESPRKGAAPAPPRKTGPAAAQVQVGK 470
Query: 930 GDEDS-SDSPDSEETPRASSPHQAGLGLSLTPSPESPPLPDVSAFSRGRGGG 980
+EDS S S +S+ A + A L SP+ P + G+G G
Sbjct: 471 QEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAG 522
Score = 31.2 bits (69), Expect = 5.4
Identities = 23/94 (24%), Positives = 35/94 (37%), Gaps = 3/94 (3%)
Query: 802 PETHLPGTGSSVAVTEATGGTVWE---EMLQTHLGPGENTVSQETSQPPDGQEVISKPQT 858
P+ + G SS + + G E + + +G T Q TS G + KP+
Sbjct: 1033 PKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKL 1092
Query: 859 PLAARPRSISESSASSAKEDEKESSDEADKNSPR 892
P + ESS S + S E D P+
Sbjct: 1093 PEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQ 1126
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 40.4 bits (93), Expect = 0.009
Identities = 46/166 (27%), Positives = 68/166 (40%), Gaps = 25/166 (15%)
Query: 856 PQTPLAARPRSISESSASSAKEDEKESSDEADKNSPRNTA--QRGKLGD----------G 903
P TP A + +S +SS +ESSD +D P A Q LG+
Sbjct: 531 PATPSAQVGKWEEDSESSS-----EESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPA 585
Query: 904 KEHTKSSGFGWFSWFRSKPTKNASPAGDEDSSDSPDSEETPRASSPHQAGLGLSLTPSPE 963
K + +G KP N+ + E+SSDS DSEE P A + QA L + +
Sbjct: 586 KGPPQKAGPVAVQVKAEKPMDNSESS--EESSDSADSEEAPAAMTAAQAKPALKIPQTKA 643
Query: 964 SPPLPDVSAFSR------GRGGGEGRGSASSGGAAAGAGVGGLSGP 1003
P + +A ++ G G+A+S ++ A GG P
Sbjct: 644 CPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRP 689
Score = 39.7 bits (91), Expect = 0.015
Identities = 60/226 (26%), Positives = 77/226 (34%), Gaps = 35/226 (15%)
Query: 803 ETHLPGTGSSVAVTEATGGTVWEEMLQTHLGPGENTVSQETSQPPDGQEVISKPQTPLAA 862
ET G + ATG TV +L S T+ + +E S P AA
Sbjct: 128 ETEKAGKTGNSMPHPATGKTV-ANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAA 186
Query: 863 RPRSISESSASSAKEDEKESSDEAD-------------------KNSPRNTA--QRGKLG 901
+P +S A S+ ED SSDE D K SP A GK+G
Sbjct: 187 KPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVG 246
Query: 902 DGKEHTKSSGFGWFSWFRSKPTKNASPAGDEDSSDSPDSEETPRASSPHQAGLGLSLTPS 961
D K P K A +E S SEE + AG + S
Sbjct: 247 DVTPQVKGGAL--------PPAKRAKKPEEESES----SEEGSESEEEAPAGTRSQVKAS 294
Query: 962 PESPPLPDVSAFSRGRGGGEGRGSASSGGAAAGAGVGGLSGPESVS 1007
+ + SA ++G G+G A G A A A PE S
Sbjct: 295 EKILQVRAASAPAKGT-PGKGATPAPPGKAGAVASQTKAGKPEEDS 339
Score = 34.7 bits (78), Expect = 0.49
Identities = 27/100 (27%), Positives = 44/100 (44%), Gaps = 2/100 (2%)
Query: 172 NSETHFQSNSRNPCKDSPASNSGQEWPGELFPGSLLAEAQKNKPSLASESNLLQQRESGL 231
+ +TH + P K+SP + PG+ P + A Q + S + ES+ + + +
Sbjct: 890 SGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAV 949
Query: 232 SSSSYELSQYIRDAPERDDPPASAAWSPVQADVSSAGPKA 271
+S+ I P R PA A +P QA +S KA
Sbjct: 950 TSAQVIKPPLIFVDPNRS--PAGPAATPAQAQAASTPRKA 987
Score = 33.1 bits (74), Expect = 1.4
Identities = 30/111 (27%), Positives = 40/111 (36%), Gaps = 18/111 (16%)
Query: 184 PCKDSPASNSGQEWPGELFPGSLLAEAQKNKPSLASESNLLQQRESGLSSSSYELSQYIR 243
P K+SP + PG+ P A+A K + S SS E S
Sbjct: 377 PAKESPRKGAAPAPPGKTGPAVAKAQAGKREED---------------SQSSSEESDSEE 421
Query: 244 DAPERDDPPASAAWSPVQADVSSAGPKAPMKFYIPHVPVSFGPGGQLVHVG 294
+AP + P A P S+ ++P K P P GP V VG
Sbjct: 422 EAPAQAKPSGKA---PQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVG 469
Score = 31.6 bits (70), Expect = 4.1
Identities = 48/232 (20%), Positives = 85/232 (36%), Gaps = 38/232 (16%)
Query: 778 LQPGSYPAGGGAGQTGTPRP------FYSVPETHLPGTGSSVAVTEATGGT----VWEEM 827
++ S PA G G+ TP P S + P S + E++ + +
Sbjct: 300 VRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKAL 359
Query: 828 LQTHLGPGENTVSQETSQPPDGQEVISKPQTPLAARPRSISESSASSAKEDEKESSDEAD 887
LQ + V ++ + + P P P +++++ A +ED + SS+E+D
Sbjct: 360 LQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGP-AVAKAQAGKREEDSQSSSEESD 418
Query: 888 --KNSPRNTAQRGKLGDGKEHTKSSGFGWFSWFRSKPTKNASPA---------------- 929
+ +P GK + + + + P K A+PA
Sbjct: 419 SEEEAPAQAKPSGKAPQVRAASAPA--------KESPRKGAAPAPPRKTGPAAAQVQVGK 470
Query: 930 GDEDS-SDSPDSEETPRASSPHQAGLGLSLTPSPESPPLPDVSAFSRGRGGG 980
+EDS S S +S+ A + A L SP+ P + G+G G
Sbjct: 471 QEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAG 522
Score = 31.6 bits (70), Expect = 4.1
Identities = 19/72 (26%), Positives = 26/72 (36%)
Query: 838 TVSQETSQPPDGQEVISKPQTPLAARPRSISESSASSAKEDEKESSDEADKNSPRNTAQR 897
T Q TS G + KP+ P + ESS S + S E D P+
Sbjct: 1110 TSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSA 1169
Query: 898 GKLGDGKEHTKS 909
LG T++
Sbjct: 1170 HTLGPTPSRTET 1181
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a [Homo
sapiens]
Length = 1450
Score = 40.4 bits (93), Expect = 0.009
Identities = 46/166 (27%), Positives = 68/166 (40%), Gaps = 25/166 (15%)
Query: 856 PQTPLAARPRSISESSASSAKEDEKESSDEADKNSPRNTA--QRGKLGD----------G 903
P TP A + +S +SS +ESSD +D P A Q LG+
Sbjct: 531 PATPSAQVGKWEEDSESSS-----EESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPA 585
Query: 904 KEHTKSSGFGWFSWFRSKPTKNASPAGDEDSSDSPDSEETPRASSPHQAGLGLSLTPSPE 963
K + +G KP N+ + E+SSDS DSEE P A + QA L + +
Sbjct: 586 KGPPQKAGPVAVQVKAEKPMDNSESS--EESSDSADSEEAPAAMTAAQAKPALKIPQTKA 643
Query: 964 SPPLPDVSAFSR------GRGGGEGRGSASSGGAAAGAGVGGLSGP 1003
P + +A ++ G G+A+S ++ A GG P
Sbjct: 644 CPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRP 689
Score = 39.7 bits (91), Expect = 0.015
Identities = 60/226 (26%), Positives = 77/226 (34%), Gaps = 35/226 (15%)
Query: 803 ETHLPGTGSSVAVTEATGGTVWEEMLQTHLGPGENTVSQETSQPPDGQEVISKPQTPLAA 862
ET G + ATG TV +L S T+ + +E S P AA
Sbjct: 128 ETEKAGKTGNSMPHPATGKTV-ANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAA 186
Query: 863 RPRSISESSASSAKEDEKESSDEAD-------------------KNSPRNTA--QRGKLG 901
+P +S A S+ ED SSDE D K SP A GK+G
Sbjct: 187 KPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVG 246
Query: 902 DGKEHTKSSGFGWFSWFRSKPTKNASPAGDEDSSDSPDSEETPRASSPHQAGLGLSLTPS 961
D K P K A +E S SEE + AG + S
Sbjct: 247 DVTPQVKGGAL--------PPAKRAKKPEEESES----SEEGSESEEEAPAGTRSQVKAS 294
Query: 962 PESPPLPDVSAFSRGRGGGEGRGSASSGGAAAGAGVGGLSGPESVS 1007
+ + SA ++G G+G A G A A A PE S
Sbjct: 295 EKILQVRAASAPAKGT-PGKGATPAPPGKAGAVASQTKAGKPEEDS 339
Score = 34.7 bits (78), Expect = 0.49
Identities = 27/100 (27%), Positives = 44/100 (44%), Gaps = 2/100 (2%)
Query: 172 NSETHFQSNSRNPCKDSPASNSGQEWPGELFPGSLLAEAQKNKPSLASESNLLQQRESGL 231
+ +TH + P K+SP + PG+ P + A Q + S + ES+ + + +
Sbjct: 890 SGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAV 949
Query: 232 SSSSYELSQYIRDAPERDDPPASAAWSPVQADVSSAGPKA 271
+S+ I P R PA A +P QA +S KA
Sbjct: 950 TSAQVIKPPLIFVDPNRS--PAGPAATPAQAQAASTPRKA 987
Score = 34.3 bits (77), Expect = 0.64
Identities = 26/111 (23%), Positives = 40/111 (36%), Gaps = 3/111 (2%)
Query: 802 PETHLPGTGSSVAVTEATGGTVWE---EMLQTHLGPGENTVSQETSQPPDGQEVISKPQT 858
P+ + G SS + + G E + + +G T Q TS G + KP+
Sbjct: 1033 PKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKL 1092
Query: 859 PLAARPRSISESSASSAKEDEKESSDEADKNSPRNTAQRGKLGDGKEHTKS 909
P + ESS S + S E D P+ LG T++
Sbjct: 1093 PEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTET 1143
Score = 33.1 bits (74), Expect = 1.4
Identities = 30/111 (27%), Positives = 40/111 (36%), Gaps = 18/111 (16%)
Query: 184 PCKDSPASNSGQEWPGELFPGSLLAEAQKNKPSLASESNLLQQRESGLSSSSYELSQYIR 243
P K+SP + PG+ P A+A K + S SS E S
Sbjct: 377 PAKESPRKGAAPAPPGKTGPAVAKAQAGKREED---------------SQSSSEESDSEE 421
Query: 244 DAPERDDPPASAAWSPVQADVSSAGPKAPMKFYIPHVPVSFGPGGQLVHVG 294
+AP + P A P S+ ++P K P P GP V VG
Sbjct: 422 EAPAQAKPSGKA---PQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVG 469
Score = 31.6 bits (70), Expect = 4.1
Identities = 48/232 (20%), Positives = 85/232 (36%), Gaps = 38/232 (16%)
Query: 778 LQPGSYPAGGGAGQTGTPRP------FYSVPETHLPGTGSSVAVTEATGGT----VWEEM 827
++ S PA G G+ TP P S + P S + E++ + +
Sbjct: 300 VRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKAL 359
Query: 828 LQTHLGPGENTVSQETSQPPDGQEVISKPQTPLAARPRSISESSASSAKEDEKESSDEAD 887
LQ + V ++ + + P P P +++++ A +ED + SS+E+D
Sbjct: 360 LQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGP-AVAKAQAGKREEDSQSSSEESD 418
Query: 888 --KNSPRNTAQRGKLGDGKEHTKSSGFGWFSWFRSKPTKNASPA---------------- 929
+ +P GK + + + + P K A+PA
Sbjct: 419 SEEEAPAQAKPSGKAPQVRAASAPA--------KESPRKGAAPAPPRKTGPAAAQVQVGK 470
Query: 930 GDEDS-SDSPDSEETPRASSPHQAGLGLSLTPSPESPPLPDVSAFSRGRGGG 980
+EDS S S +S+ A + A L SP+ P + G+G G
Sbjct: 471 QEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAG 522
>gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c [Homo
sapiens]
Length = 958
Score = 40.4 bits (93), Expect = 0.009
Identities = 46/166 (27%), Positives = 68/166 (40%), Gaps = 25/166 (15%)
Query: 856 PQTPLAARPRSISESSASSAKEDEKESSDEADKNSPRNTA--QRGKLGD----------G 903
P TP A + +S +SS +ESSD +D P A Q LG+
Sbjct: 531 PATPSAQVGKWEEDSESSS-----EESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPA 585
Query: 904 KEHTKSSGFGWFSWFRSKPTKNASPAGDEDSSDSPDSEETPRASSPHQAGLGLSLTPSPE 963
K + +G KP N+ + E+SSDS DSEE P A + QA L + +
Sbjct: 586 KGPPQKAGPVAVQVKAEKPMDNSESS--EESSDSADSEEAPAAMTAAQAKPALKIPQTKA 643
Query: 964 SPPLPDVSAFSR------GRGGGEGRGSASSGGAAAGAGVGGLSGP 1003
P + +A ++ G G+A+S ++ A GG P
Sbjct: 644 CPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRP 689
Score = 39.7 bits (91), Expect = 0.015
Identities = 60/226 (26%), Positives = 77/226 (34%), Gaps = 35/226 (15%)
Query: 803 ETHLPGTGSSVAVTEATGGTVWEEMLQTHLGPGENTVSQETSQPPDGQEVISKPQTPLAA 862
ET G + ATG TV +L S T+ + +E S P AA
Sbjct: 128 ETEKAGKTGNSMPHPATGKTV-ANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAA 186
Query: 863 RPRSISESSASSAKEDEKESSDEAD-------------------KNSPRNTA--QRGKLG 901
+P +S A S+ ED SSDE D K SP A GK+G
Sbjct: 187 KPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVG 246
Query: 902 DGKEHTKSSGFGWFSWFRSKPTKNASPAGDEDSSDSPDSEETPRASSPHQAGLGLSLTPS 961
D K P K A +E S SEE + AG + S
Sbjct: 247 DVTPQVKGGAL--------PPAKRAKKPEEESES----SEEGSESEEEAPAGTRSQVKAS 294
Query: 962 PESPPLPDVSAFSRGRGGGEGRGSASSGGAAAGAGVGGLSGPESVS 1007
+ + SA ++G G+G A G A A A PE S
Sbjct: 295 EKILQVRAASAPAKGT-PGKGATPAPPGKAGAVASQTKAGKPEEDS 339
Score = 33.1 bits (74), Expect = 1.4
Identities = 30/111 (27%), Positives = 40/111 (36%), Gaps = 18/111 (16%)
Query: 184 PCKDSPASNSGQEWPGELFPGSLLAEAQKNKPSLASESNLLQQRESGLSSSSYELSQYIR 243
P K+SP + PG+ P A+A K + S SS E S
Sbjct: 377 PAKESPRKGAAPAPPGKTGPAVAKAQAGKREED---------------SQSSSEESDSEE 421
Query: 244 DAPERDDPPASAAWSPVQADVSSAGPKAPMKFYIPHVPVSFGPGGQLVHVG 294
+AP + P A P S+ ++P K P P GP V VG
Sbjct: 422 EAPAQAKPSGKA---PQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVG 469
Score = 31.6 bits (70), Expect = 4.1
Identities = 48/232 (20%), Positives = 85/232 (36%), Gaps = 38/232 (16%)
Query: 778 LQPGSYPAGGGAGQTGTPRP------FYSVPETHLPGTGSSVAVTEATGGT----VWEEM 827
++ S PA G G+ TP P S + P S + E++ + +
Sbjct: 300 VRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKAL 359
Query: 828 LQTHLGPGENTVSQETSQPPDGQEVISKPQTPLAARPRSISESSASSAKEDEKESSDEAD 887
LQ + V ++ + + P P P +++++ A +ED + SS+E+D
Sbjct: 360 LQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGP-AVAKAQAGKREEDSQSSSEESD 418
Query: 888 --KNSPRNTAQRGKLGDGKEHTKSSGFGWFSWFRSKPTKNASPA---------------- 929
+ +P GK + + + + P K A+PA
Sbjct: 419 SEEEAPAQAKPSGKAPQVRAASAPA--------KESPRKGAAPAPPRKTGPAAAQVQVGK 470
Query: 930 GDEDS-SDSPDSEETPRASSPHQAGLGLSLTPSPESPPLPDVSAFSRGRGGG 980
+EDS S S +S+ A + A L SP+ P + G+G G
Sbjct: 471 QEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAG 522
>gi|51479192 ring finger protein 1 [Homo sapiens]
Length = 406
Score = 40.4 bits (93), Expect = 0.009
Identities = 34/108 (31%), Positives = 47/108 (43%), Gaps = 7/108 (6%)
Query: 919 RSKPTKNASPAGDEDSSDSPDSEETPRASSPHQAGLGLSLTPSPESPPLPDVSAFSRGRG 978
R++ + P D+ ++ S E G +S +P+S P P A R RG
Sbjct: 152 RAQRVRRPIPGSDQTTTMSGGEGEPGEGEGD---GEDVSSDSAPDSAPGP---APKRPRG 205
Query: 979 GGEGRGSASSGGAAAGAGVGGLSGPESVSFELCSNPGVLLPPPALKGA 1026
GG G S +GG G GVGG +G E + G L PP+ GA
Sbjct: 206 GGAGGSSVGTGGGGTG-GVGGGAGSEDSGDRGGTLGGGTLGPPSPPGA 252
Score = 32.7 bits (73), Expect = 1.9
Identities = 35/121 (28%), Positives = 39/121 (32%), Gaps = 27/121 (22%)
Query: 901 GDGKEHTKSSGFGWFSWFRSKPTKNASPAGDEDSSDSPDSEETPRASSPHQAGLGLSLTP 960
G + T S G G +P + D S +PDS P P G G S
Sbjct: 162 GSDQTTTMSGGEG-------EPGEGEGDGEDVSSDSAPDSAPGPAPKRPRGGGAGGS--- 211
Query: 961 SPESPPLPDVSAFSRGRGG-GEGRGSASSGGAAAGAGVGGLSGPESVSFELCSNPGVLLP 1019
V G GG G G GS SG G G L P S PG P
Sbjct: 212 --------SVGTGGGGTGGVGGGAGSEDSGDRGGTLGGGTLGPP--------SPPGAPSP 255
Query: 1020 P 1020
P
Sbjct: 256 P 256
>gi|166795264 AE binding protein 2 isoform b [Homo sapiens]
Length = 517
Score = 40.4 bits (93), Expect = 0.009
Identities = 44/151 (29%), Positives = 58/151 (38%), Gaps = 29/151 (19%)
Query: 868 SESSASSAKEDEKESSDEADKNSPRNTAQRGKLGDGKEHTKSSGFGWFSWFRSKPTKNAS 927
S SAS A EDE E D+ ++ +++ G+ +E + S G S T++ S
Sbjct: 86 SPESASQAGEDEDEEEDDEEEEDESSSSGGGE----EESSAESLVGSSGGSSSDETRSLS 141
Query: 928 PAGDEDSSDSPDSEETPRASSPHQAGLGLSLTPSPESPPLPDVSAFSRGRGGGEGRGSAS 987
P SS D +E GL E P P S G GGG S
Sbjct: 142 PGAASSSSGDGDGKE----------GL--------EEPKGPRGS--QGGGGGGSSSSSVV 181
Query: 988 SGGAAAGAGVGG-----LSGPESVSFELCSN 1013
S G G G GG SG S E+ S+
Sbjct: 182 SSGGDEGYGTGGGGSSATSGGRRGSLEMSSD 212
Score = 33.1 bits (74), Expect = 1.4
Identities = 33/141 (23%), Positives = 50/141 (35%), Gaps = 9/141 (6%)
Query: 876 KEDEKESSDEADKNSPRNTAQRGKLGDGKEHTKSSGFGWFSWFRSKPTKNASPAGDEDSS 935
+E+E+E +EA+ + G G G G + S+P+ ++ ED
Sbjct: 39 EEEEEEEEEEAEAEAVAALLLNGGSGGGGGGGGGGVGGGEAETMSEPSPESASQAGEDED 98
Query: 936 DSPDSEETPRASSPHQAG---------LGLSLTPSPESPPLPDVSAFSRGRGGGEGRGSA 986
+ D EE SS G +G S S + A S G G+G+
Sbjct: 99 EEEDDEEEEDESSSSGGGEEESSAESLVGSSGGSSSDETRSLSPGAASSSSGDGDGKEGL 158
Query: 987 SSGGAAAGAGVGGLSGPESVS 1007
G+ GG G S S
Sbjct: 159 EEPKGPRGSQGGGGGGSSSSS 179
>gi|166795262 AE binding protein 2 isoform a [Homo sapiens]
Length = 503
Score = 40.4 bits (93), Expect = 0.009
Identities = 44/151 (29%), Positives = 58/151 (38%), Gaps = 29/151 (19%)
Query: 868 SESSASSAKEDEKESSDEADKNSPRNTAQRGKLGDGKEHTKSSGFGWFSWFRSKPTKNAS 927
S SAS A EDE E D+ ++ +++ G+ +E + S G S T++ S
Sbjct: 86 SPESASQAGEDEDEEEDDEEEEDESSSSGGGE----EESSAESLVGSSGGSSSDETRSLS 141
Query: 928 PAGDEDSSDSPDSEETPRASSPHQAGLGLSLTPSPESPPLPDVSAFSRGRGGGEGRGSAS 987
P SS D +E GL E P P S G GGG S
Sbjct: 142 PGAASSSSGDGDGKE----------GL--------EEPKGPRGS--QGGGGGGSSSSSVV 181
Query: 988 SGGAAAGAGVGG-----LSGPESVSFELCSN 1013
S G G G GG SG S E+ S+
Sbjct: 182 SSGGDEGYGTGGGGSSATSGGRRGSLEMSSD 212
Score = 33.1 bits (74), Expect = 1.4
Identities = 33/141 (23%), Positives = 50/141 (35%), Gaps = 9/141 (6%)
Query: 876 KEDEKESSDEADKNSPRNTAQRGKLGDGKEHTKSSGFGWFSWFRSKPTKNASPAGDEDSS 935
+E+E+E +EA+ + G G G G + S+P+ ++ ED
Sbjct: 39 EEEEEEEEEEAEAEAVAALLLNGGSGGGGGGGGGGVGGGEAETMSEPSPESASQAGEDED 98
Query: 936 DSPDSEETPRASSPHQAG---------LGLSLTPSPESPPLPDVSAFSRGRGGGEGRGSA 986
+ D EE SS G +G S S + A S G G+G+
Sbjct: 99 EEEDDEEEEDESSSSGGGEEESSAESLVGSSGGSSSDETRSLSPGAASSSSGDGDGKEGL 158
Query: 987 SSGGAAAGAGVGGLSGPESVS 1007
G+ GG G S S
Sbjct: 159 EEPKGPRGSQGGGGGGSSSSS 179
>gi|195539337 S-adenosylhomocysteine hydrolase-like 2 isoform b
[Homo sapiens]
Length = 610
Score = 40.0 bits (92), Expect = 0.012
Identities = 41/155 (26%), Positives = 61/155 (39%), Gaps = 27/155 (17%)
Query: 784 PAGGGAGQTGTPRPFYSVPETHLPGTGSSVAVTEATGGTVWEEML---------QTHLGP 834
PAGGG + P P P PG+G + A++ A G + Q H
Sbjct: 44 PAGGGDPEA--PAPAAERPPVPGPGSGPAAALSPAAGKVPQASAMKRSDPHHQHQRHRDG 101
Query: 835 GENTVSQETS-----------QPPDGQEVISKPQTPLAARP--RSISESSASSAKEDEKE 881
GE VS + + Q D ++ +K T + R RSIS+SS S
Sbjct: 102 GEALVSPDGTVTEAPRTVKKIQFADQKQEFNKRPTKIGRRSLSRSISQSSTDSYSSAASY 161
Query: 882 SSDEADKNSPRNTAQRGKLGDGK---EHTKSSGFG 913
+ D+ SPR+ Q+ G ++ K + FG
Sbjct: 162 TDSSDDETSPRDKQQKNSKGSSDFCVKNIKQAEFG 196
>gi|118498345 AT-binding transcription factor 1 [Homo sapiens]
Length = 3703
Score = 40.0 bits (92), Expect = 0.012
Identities = 44/172 (25%), Positives = 65/172 (37%), Gaps = 29/172 (16%)
Query: 852 VISKPQTPLAARPRSISESSASSAKEDEKE--------------SSDEADKNSPRNTAQR 897
+ S P PLA+ P SE S A E EK+ + +EA++ A+
Sbjct: 415 ITSVPLGPLASSPTKSSEGKDSGAAEGEKQEVGDGDCFSEKVEPAEEEAEEEEEEEEAEE 474
Query: 898 GKLGDGKEHTKSSGFGWFSWFRSKPTKNASPAGDEDSSDSPDSEETPRASSPHQAGLGLS 957
+ + +E + G F S+ DE+ D P E A S + L LS
Sbjct: 475 EEEEEEEEEEEEEDEGCKGLFPSEL--------DEELEDRPHEEPGAAAGSSSKKDLALS 526
Query: 958 LTPSPESPPLPDV-SAFSRGRGGGEGRGSASSGGAAAGAGVGGLSGPESVSF 1008
SP +P+V SR G S SS A++ G + +SF
Sbjct: 527 NQSISNSPLMPNVLQTLSR------GTASTSSNSASSFVVFDGANRRNRLSF 572
Score = 40.0 bits (92), Expect = 0.012
Identities = 82/340 (24%), Positives = 121/340 (35%), Gaps = 29/340 (8%)
Query: 684 PLVLERRSGDRDLEPDWLAQLRRQLEQKVAGDIGDPHPTRSDISGAGGTTTENTFYQDFS 743
PL +++ D+D E + + ++K G+P P G T T T
Sbjct: 3225 PLQQQQQRKDKDSE-------KVKEKEKAHKGKGEPLPVPKKEKGEAPTATAATISAPLP 3277
Query: 744 GCQGYSEAPGYRSALW--LTPEQTCLL--QPSPQQPFPLQPGSYPAGGGAGQTGTPRPFY 799
+ Y+ P AL LT + T LL Q P P P GA Q+G +P Y
Sbjct: 3278 TME-YAVDPAQLQALQAALTSDPTALLTSQFLPYFVPGFSPYYAPQIPGALQSGYLQPMY 3336
Query: 800 SVPETHLPGTGSSVAVTEATGGTVWEEMLQTHLGPGENTVSQETSQPPDGQEVISKPQTP 859
+ S A+ + G++ ++ Q E Q+ Q Q+ + Q P
Sbjct: 3337 GMEGLFPYSPALSQALMGLSPGSLLQQYQQYQQSLQEAIQQQQQRQLQQQQQQKVQQQQP 3396
Query: 860 LAARPRSISESSASSAKEDEKES-SDEADKNSPRNTAQR-GKLGDGKEHTKSSGFGWFSW 917
A++ + + S K+ KES E KN+PR + KL + E S +
Sbjct: 3397 KASQT-PVPPGAPSPDKDPAKESPKPEEQKNTPREVSPLLPKLPEEPEAESKSADSLYDP 3455
Query: 918 F-----RSKPTKNASPAGDEDSSDSPDSEETPRASSPHQAGLGLSLTPSPESPPLPDVSA 972
F + K AG D EE R+ G S+ E
Sbjct: 3456 FIVPKVQYKLVCRKCQAGFSD-------EEAARSHLKSLCFFGQSVVNLQEMVLHVPTGG 3508
Query: 973 FSRGRGGGEGRGSASSGGAA--AGAGVGGLSGPESVSFEL 1010
G GGG G G GG + A L G E++S L
Sbjct: 3509 GGGGSGGGGGGGGGGGGGGSYHCLACESALCGEEALSQHL 3548
Score = 32.3 bits (72), Expect = 2.4
Identities = 32/144 (22%), Positives = 53/144 (36%), Gaps = 36/144 (25%)
Query: 761 TPEQTCLLQPSPQQPFPLQPGSYPAGGGAGQTGTPRPFYSVPETHLPGTGSSVAVTEATG 820
TP T L P P G T P P +P + LP SS +++ T
Sbjct: 3138 TPSNTALTSPKPNLM------------GLPSTTVPSP--GLPTSGLPNKPSSASLSSPT- 3182
Query: 821 GTVWEEMLQTHLGPGENTVSQETSQPPDGQEVISKPQT-----PLAARPRSISESSASSA 875
P + T++ QPP Q+ +PQ P AA+P +
Sbjct: 3183 -------------PAQATMAMGPQQPPQQQQQQQQPQVQQPPPPPAAQP---PPTPQLPL 3226
Query: 876 KEDEKESSDEADKNSPRNTAQRGK 899
++ ++ +++K + A +GK
Sbjct: 3227 QQQQQRKDKDSEKVKEKEKAHKGK 3250
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 40.0 bits (92), Expect = 0.012
Identities = 68/289 (23%), Positives = 102/289 (35%), Gaps = 24/289 (8%)
Query: 770 PSPQQPFPLQPGSYPAGGGAGQTGTPRPFYSVPETHLPGTGSSVAVTEATGGTVWEEMLQ 829
PSP P P G T P S P+ P S + T ++ GT+ L
Sbjct: 735 PSPSLPPAGTPPGTKKVDGISHTSALAPVASSPK-ECPTEDSGASATASSKGTL--TYLA 791
Query: 830 THLGPGENTVSQETSQPPDGQEVISKPQTPLAARPRSISESSASSAKEDEKESSDEADKN 889
P +VS +T +PP ++ + P TP+ +S AS E+ S + K+
Sbjct: 792 DSPSPLGVSVSPQTKRPPT-KKGSAGPDTPIGNLSSPVSPVEASFLPENSL--SFQGSKD 848
Query: 890 SPRNTAQRGKLGDGKEHTKS-----SGFGWFSWFRSKPTKN-----------ASPAGDED 933
SP T T S S G + PT + A+PA +
Sbjct: 849 SPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQA 908
Query: 934 SSDSPDSEETPRASSPHQAGLGLSLTPSPESPPLPDVSAFSRGRGGGEGRGSASSGGAAA 993
+ S S +P+ + A G+ +PSP+ P P + +GG + A
Sbjct: 909 PALSMTSS-SPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPA 967
Query: 994 GAGVGGLSGPESVSFELCSNPGVLLPPPALKGAVPLYNPSQVPQLPTAT 1042
GP + S + P PP+ KG +P P P T
Sbjct: 968 ATPPSPKGGPATPSPKGAPTPPA-ATPPSPKGGPATPSPKGAPTPPAVT 1015
Score = 38.1 bits (87), Expect = 0.044
Identities = 60/253 (23%), Positives = 90/253 (35%), Gaps = 43/253 (16%)
Query: 835 GENTVSQETSQPPDGQEVISKPQ---TPLAARPRSISESSASSAKEDEKESSDEADKNSP 891
G T T P G P+ TP A P S S A++ + A SP
Sbjct: 984 GAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSP 1043
Query: 892 RNTAQRGKLGDGKEHTKSSGFGWFSWFRSKPTKNASPAGDEDSSDSPDSEETPRASSPHQ 951
+ + L G T ++ + P+ PA + S TP A++P
Sbjct: 1044 KGSPAATPLPKGAPTTPAA---------TLPSPKGGPA-----TPSLKGAPTPPAATP-P 1088
Query: 952 AGLGLSLTPSPESPPLPDVSAFSRGRGG---GEGRGSASSGGAAAGAGVGGLSGPE---- 1004
+ G TPSP+ P+P + +GG +G+ ++ A + GGL+ P
Sbjct: 1089 SPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGA 1148
Query: 1005 ---------SVSFELCSNPGVLLP------PPALKGAVPLYNPSQVPQLPTATSLNRPNR 1049
S L + P P PP+ KG + +P P P AT +
Sbjct: 1149 PTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGG 1208
Query: 1050 LA---QRRYPTQP 1059
LA + PT P
Sbjct: 1209 LATPSPKGAPTTP 1221
Score = 34.7 bits (78), Expect = 0.49
Identities = 75/315 (23%), Positives = 103/315 (32%), Gaps = 31/315 (9%)
Query: 752 PGYRSALWLTPEQTCLLQPSPQQPFPLQPGSYPAGGGAGQTGTPRPFYSVPETHLP-GTG 810
P S W P PSP+ P P P G TP P T P G
Sbjct: 954 PATPSPKW-APTPPAATPPSPKGG-PATPS--PKGAPTPPAATPPSPKGGPATPSPKGAP 1009
Query: 811 SSVAVTEATGGTVWEEMLQTHLGPGENTVSQETSQPPDGQEVISKPQTPLAARPRSISES 870
+ AVT + T G +T T P G S TPL + +
Sbjct: 1010 TPPAVTPPSPKG---SPAATPFPKGASTPPAATPPSPKG----SPAATPLPKGAPTTPAA 1062
Query: 871 SASSAKEDEKESSDEADKNSPRNTAQRGKLGDGKEHTKSSGFGWFSWFRSKPTKNASPAG 930
+ S K S + P T K G K + SP G
Sbjct: 1063 TLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPM-------PPAATPPSPKG 1115
Query: 931 DEDSSDSPDSEETPRASSPHQAGLGLSLTPSPESPPLPDVSAFSRGRGG---GEGRGSAS 987
+ + TP A+ P G GL+ TP P+ P + +GG +G+ +
Sbjct: 1116 GLATPPHKGAPTTPAATPPSPKG-GLA-TPPPKGAPTTPAATPPSPKGGLATPPPKGAPT 1173
Query: 988 SGGAAAGAGVGGLSGPESVSFELCSNPGVLLPPPALKGAVPLYNPSQVPQLPTATSLNRP 1047
+ A + GGL+ P + P PP+ KG + +P P P AT +
Sbjct: 1174 TPAATPPSPKGGLATPSPKGAP--TTPAAT--PPSPKGGLATPSPKGAPTTPAATPPSPK 1229
Query: 1048 NRLA---QRRYPTQP 1059
LA + PT P
Sbjct: 1230 GGLATPSPKGAPTTP 1244
Score = 34.3 bits (77), Expect = 0.64
Identities = 32/119 (26%), Positives = 49/119 (41%), Gaps = 9/119 (7%)
Query: 927 SPAGDEDSSDSPDSEETPRASSPHQAGLGLSLTPSPESPPLPDVSAFSRGRGG---GEGR 983
SP G + + TP A+ P G GL+ TP P+ P + +GG +
Sbjct: 1135 SPKGGLATPPPKGAPTTPAATPPSPKG-GLA-TPPPKGAPTTPAATPPSPKGGLATPSPK 1192
Query: 984 GSASSGGAAAGAGVGGLSGPESVSFELCSNPGVLLPPPALKGAVPLYNPSQVPQLPTAT 1042
G+ ++ A + GGL+ P + P PP+ KG + +P P P AT
Sbjct: 1193 GAPTTPAATPPSPKGGLATPSPKGAP--TTPAAT--PPSPKGGLATPSPKGAPTTPAAT 1247
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.131 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 50,603,619
Number of Sequences: 37866
Number of extensions: 2886519
Number of successful extensions: 16022
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 108
Number of HSP's successfully gapped in prelim test: 595
Number of HSP's that attempted gapping in prelim test: 13025
Number of HSP's gapped (non-prelim): 3026
length of query: 1060
length of database: 18,247,518
effective HSP length: 113
effective length of query: 947
effective length of database: 13,968,660
effective search space: 13228321020
effective search space used: 13228321020
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.