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Search of human proteins with 116235446
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|116235446 LAG1 longevity assurance homolog 3 [Homo sapiens]
(383 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|116235446 LAG1 longevity assurance homolog 3 [Homo sapiens] 811 0.0
gi|32455256 LAG1 longevity assurance 2 [Homo sapiens] 423 e-118
gi|31077094 LAG1 longevity assurance 2 [Homo sapiens] 423 e-118
gi|205360977 LAG1 homolog, ceramide synthase 4 [Homo sapiens] 345 4e-95
gi|22218345 LAG1 homolog, ceramide synthase 5 [Homo sapiens] 305 3e-83
gi|45007002 longevity assurance homolog 6 [Homo sapiens] 298 4e-81
gi|11641421 LAG1 homolog, ceramide synthase 1 isoform 1 [Homo sa... 87 3e-17
gi|38176296 LAG1 homolog, ceramide synthase 1 isoform 2 [Homo sa... 84 3e-16
gi|7657655 translocation associated membrane protein 1 [Homo sap... 45 8e-05
gi|6912450 translocation-associated membrane protein 2 [Homo sap... 40 0.005
gi|60498973 myelin transcription factor 1-like [Homo sapiens] 38 0.017
gi|56711320 hypothetical protein LOC145407 [Homo sapiens] 37 0.030
gi|20336305 B-cell CLL/lymphoma 11A isoform 1 [Homo sapiens] 37 0.039
gi|20336307 B-cell CLL/lymphoma 11A isoform 2 [Homo sapiens] 37 0.039
gi|198041755 pre-B-cell leukemia homeobox 3 isoform 2 [Homo sapi... 37 0.039
gi|5453852 pre-B-cell leukemia homeobox 3 isoform 1 [Homo sapiens] 37 0.039
gi|4503257 death-domain associated protein isoform a [Homo sapiens] 36 0.051
gi|215422388 death-domain associated protein isoform a [Homo sap... 36 0.051
gi|215422366 death-domain associated protein isoform b [Homo sap... 36 0.051
gi|55741655 anoctamin 8 [Homo sapiens] 36 0.066
gi|4505623 pre-B-cell leukemia homeobox 1 [Homo sapiens] 36 0.066
gi|145580602 translocation associated membrane protein 1-like 1 ... 36 0.066
gi|51477718 TATA box binding protein-associated factor, RNA poly... 35 0.11
gi|121114296 caudal type homeobox 1 [Homo sapiens] 35 0.11
gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex... 35 0.11
gi|4759208 TAO kinase 2 isoform 1 [Homo sapiens] 35 0.15
gi|45505130 TAO kinase 2 isoform 2 [Homo sapiens] 35 0.15
gi|27436887 pre-B-cell leukemia homeobox 2 [Homo sapiens] 35 0.15
gi|169636435 caudal type homeobox 2 [Homo sapiens] 34 0.19
gi|48255900 SWI/SNF-related matrix-associated actin-dependent re... 34 0.19
>gi|116235446 LAG1 longevity assurance homolog 3 [Homo sapiens]
Length = 383
Score = 811 bits (2096), Expect = 0.0
Identities = 383/383 (100%), Positives = 383/383 (100%)
Query: 1 MFWTFKEWFWLERFWLPPTIKWSDLEDHDGLVFVKPSHLYVTIPYAFLLLIIRRVFEKFV 60
MFWTFKEWFWLERFWLPPTIKWSDLEDHDGLVFVKPSHLYVTIPYAFLLLIIRRVFEKFV
Sbjct: 1 MFWTFKEWFWLERFWLPPTIKWSDLEDHDGLVFVKPSHLYVTIPYAFLLLIIRRVFEKFV 60
Query: 61 ASPLAKSFGIKETVRKVTPNTVLENFFKHSTRQPLQTDIYGLAKKCNLTERQVERWFRSR 120
ASPLAKSFGIKETVRKVTPNTVLENFFKHSTRQPLQTDIYGLAKKCNLTERQVERWFRSR
Sbjct: 61 ASPLAKSFGIKETVRKVTPNTVLENFFKHSTRQPLQTDIYGLAKKCNLTERQVERWFRSR 120
Query: 121 RNQERPSRLKKFQEACWRFAFYLMITVAGIAFLYDKPWLYDLWEVWNGYPKQPLLPSQYW 180
RNQERPSRLKKFQEACWRFAFYLMITVAGIAFLYDKPWLYDLWEVWNGYPKQPLLPSQYW
Sbjct: 121 RNQERPSRLKKFQEACWRFAFYLMITVAGIAFLYDKPWLYDLWEVWNGYPKQPLLPSQYW 180
Query: 181 YYILEMSFYWSLLFRLGFDVKRKDFLAHIIHHLAAISLMSFSWCANYIRSGTLVMIVHDV 240
YYILEMSFYWSLLFRLGFDVKRKDFLAHIIHHLAAISLMSFSWCANYIRSGTLVMIVHDV
Sbjct: 181 YYILEMSFYWSLLFRLGFDVKRKDFLAHIIHHLAAISLMSFSWCANYIRSGTLVMIVHDV 240
Query: 241 ADIWLESAKMFSYAGWTQTCNTLFFIFSTIFFISRLIVFPFWILYCTLILPMYHLEPFFS 300
ADIWLESAKMFSYAGWTQTCNTLFFIFSTIFFISRLIVFPFWILYCTLILPMYHLEPFFS
Sbjct: 241 ADIWLESAKMFSYAGWTQTCNTLFFIFSTIFFISRLIVFPFWILYCTLILPMYHLEPFFS 300
Query: 301 YIFLNLQLMILQVLHLYWGYYILKMLNRCIFMKSIQDVRSDDEDYEEEEEEEEEEATKGK 360
YIFLNLQLMILQVLHLYWGYYILKMLNRCIFMKSIQDVRSDDEDYEEEEEEEEEEATKGK
Sbjct: 301 YIFLNLQLMILQVLHLYWGYYILKMLNRCIFMKSIQDVRSDDEDYEEEEEEEEEEATKGK 360
Query: 361 EMDCLKNGLRAERHLIPNGQHGH 383
EMDCLKNGLRAERHLIPNGQHGH
Sbjct: 361 EMDCLKNGLRAERHLIPNGQHGH 383
>gi|32455256 LAG1 longevity assurance 2 [Homo sapiens]
Length = 380
Score = 423 bits (1088), Expect = e-118
Identities = 201/382 (52%), Positives = 263/382 (68%), Gaps = 7/382 (1%)
Query: 1 MFWTFKEWFWLERFWLPPTIKWSDLEDHDGLVFVKPSHLYVTIPYAFLLLIIRRVFEKFV 60
M T ++FW ER WLP + W+DLED DG V+ K S LY+T+P A L LI+R FE +V
Sbjct: 1 MLQTLYDYFWWERLWLPVNLTWADLEDRDGRVYAKASDLYITLPLALLFLIVRYFFELYV 60
Query: 61 ASPLAKSFGIKETVR-KVTPNTVLENFFKHSTRQPLQTDIYGLAKKCNLTERQVERWFRS 119
A+PLA IKE R + PN LE+F+ S +QP Q ++ L+++ L+ RQVERWFR
Sbjct: 61 ATPLAALLNIKEKTRLRAPPNATLEHFYLTSGKQPKQVEVELLSRQSGLSGRQVERWFRR 120
Query: 120 RRNQERPSRLKKFQEACWRFAFYLMITVAGIAFLYDKPWLYDLWEVWNGYPKQPLLPSQY 179
RRNQ+RPS LKKF+EA WRF FYL+ +AG+A + DKPW YD+ +VW GYP Q +PSQY
Sbjct: 121 RRNQDRPSLLKKFREASWRFTFYLIAFIAGMAVIVDKPWFYDMKKVWEGYPIQSTIPSQY 180
Query: 180 WYYILEMSFYWSLLFRLGFDVKRKDFLAHIIHHLAAISLMSFSWCANYIRSGTLVMIVHD 239
WYY++E+SFYWSLLF + DVKRKDF IIHH+A I L+SFSW ANYIR+GTL+M +HD
Sbjct: 181 WYYMIELSFYWSLLFSIASDVKRKDFKEQIIHHVATIILISFSWFANYIRAGTLIMALHD 240
Query: 240 VADIWLESAKMFSYAGWTQTCNTLFFIFSTIFFISRLIVFPFWILYCTLILPMYHLEPFF 299
+D LESAKMF+YAGW TCN +F +F+ +F I+RL++ PFWIL+CTL+ P+ FF
Sbjct: 241 SSDYLLESAKMFNYAGWKNTCNNIFIVFAIVFIITRLVILPFWILHCTLVYPLELYPAFF 300
Query: 300 SYIFLNLQLMILQVLHLYWGYYILKMLNRCIFMKSIQDVRSDDEDYEEEEEEEEEEATKG 359
Y F N + +LQ+LH++W Y IL+M ++ I K ++D RSD E+ E E EE A G
Sbjct: 301 GYYFFNSMMGVLQLLHIFWAYLILRMAHKFITGKLVEDERSDREE-TESSEGEEAAAGGG 359
Query: 360 KEMDCLKNGLRAERHLIPNGQH 381
+ L NG H I N H
Sbjct: 360 AKSRPLANG-----HPILNNNH 376
>gi|31077094 LAG1 longevity assurance 2 [Homo sapiens]
Length = 380
Score = 423 bits (1088), Expect = e-118
Identities = 201/382 (52%), Positives = 263/382 (68%), Gaps = 7/382 (1%)
Query: 1 MFWTFKEWFWLERFWLPPTIKWSDLEDHDGLVFVKPSHLYVTIPYAFLLLIIRRVFEKFV 60
M T ++FW ER WLP + W+DLED DG V+ K S LY+T+P A L LI+R FE +V
Sbjct: 1 MLQTLYDYFWWERLWLPVNLTWADLEDRDGRVYAKASDLYITLPLALLFLIVRYFFELYV 60
Query: 61 ASPLAKSFGIKETVR-KVTPNTVLENFFKHSTRQPLQTDIYGLAKKCNLTERQVERWFRS 119
A+PLA IKE R + PN LE+F+ S +QP Q ++ L+++ L+ RQVERWFR
Sbjct: 61 ATPLAALLNIKEKTRLRAPPNATLEHFYLTSGKQPKQVEVELLSRQSGLSGRQVERWFRR 120
Query: 120 RRNQERPSRLKKFQEACWRFAFYLMITVAGIAFLYDKPWLYDLWEVWNGYPKQPLLPSQY 179
RRNQ+RPS LKKF+EA WRF FYL+ +AG+A + DKPW YD+ +VW GYP Q +PSQY
Sbjct: 121 RRNQDRPSLLKKFREASWRFTFYLIAFIAGMAVIVDKPWFYDMKKVWEGYPIQSTIPSQY 180
Query: 180 WYYILEMSFYWSLLFRLGFDVKRKDFLAHIIHHLAAISLMSFSWCANYIRSGTLVMIVHD 239
WYY++E+SFYWSLLF + DVKRKDF IIHH+A I L+SFSW ANYIR+GTL+M +HD
Sbjct: 181 WYYMIELSFYWSLLFSIASDVKRKDFKEQIIHHVATIILISFSWFANYIRAGTLIMALHD 240
Query: 240 VADIWLESAKMFSYAGWTQTCNTLFFIFSTIFFISRLIVFPFWILYCTLILPMYHLEPFF 299
+D LESAKMF+YAGW TCN +F +F+ +F I+RL++ PFWIL+CTL+ P+ FF
Sbjct: 241 SSDYLLESAKMFNYAGWKNTCNNIFIVFAIVFIITRLVILPFWILHCTLVYPLELYPAFF 300
Query: 300 SYIFLNLQLMILQVLHLYWGYYILKMLNRCIFMKSIQDVRSDDEDYEEEEEEEEEEATKG 359
Y F N + +LQ+LH++W Y IL+M ++ I K ++D RSD E+ E E EE A G
Sbjct: 301 GYYFFNSMMGVLQLLHIFWAYLILRMAHKFITGKLVEDERSDREE-TESSEGEEAAAGGG 359
Query: 360 KEMDCLKNGLRAERHLIPNGQH 381
+ L NG H I N H
Sbjct: 360 AKSRPLANG-----HPILNNNH 376
>gi|205360977 LAG1 homolog, ceramide synthase 4 [Homo sapiens]
Length = 394
Score = 345 bits (885), Expect = 4e-95
Identities = 175/372 (47%), Positives = 235/372 (63%), Gaps = 11/372 (2%)
Query: 1 MFWTFKEWFWLERFWLPPTIKWSDLEDHDGLVFVKPSHLYVTIPYAFLLLIIRRVFEKFV 60
M +F EWFW +RFWLPP + W++LED DG V+ P L +P A +LL +R FE+F+
Sbjct: 1 MLSSFNEWFWQDRFWLPPNVTWTELEDRDGRVYPHPQDLLAALPLALVLLAMRLAFERFI 60
Query: 61 ASPLAKSFGIKE-TVRKVTPNTVLENFFKHSTRQPLQTDIYGLAKKCNLTERQVERWFRS 119
PL++ G+++ T R+V PN LE F +P + + LA +C LT +Q +RWFR
Sbjct: 61 GLPLSRWLGVRDQTRRQVKPNATLEKHFLTEGHRPKEPQLSLLAAQCGLTLQQTQRWFRR 120
Query: 120 RRNQERPSRLKKFQEACWRFAFYLMITVAGIAFLYDKPWLYDLWEVWNGYPKQPLLPSQY 179
RRNQ+RP KKF EA WRF FYL V G++ LY + WL+ W+ YP Q L PS Y
Sbjct: 121 RRNQDRPQLTKKFCEASWRFLFYLSSFVGGLSVLYHESWLWAPVMCWDRYPNQTLKPSLY 180
Query: 180 WYYILEMSFYWSLLFRLGFDVKRKDFLAHIIHHLAAISLMSFSWCANYIRSGTLVMIVHD 239
W+Y+LE+ FY SLL RL FDVKRKDF +IHH A+ LM+FS+ AN +R G+LV+++HD
Sbjct: 181 WWYLLELGFYLSLLIRLPFDVKRKDFKEQVIHHFVAVILMTFSYSANLLRIGSLVLLLHD 240
Query: 240 VADIWLESAKMFSYAGWTQTCNTLFFIFSTIFFISRLIVFPFWILYCTLILPMYHLEPFF 299
+D LE+ KM +Y + Q C+ LF IFS +FF +RL++FP ILY T + + PFF
Sbjct: 241 SSDYLLEACKMVNYMQYQQVCDALFLIFSFVFFYTRLVLFPTQILYTTYYESISNRGPFF 300
Query: 300 SYIFLNLQLMILQVLHLYWGYYILKMLNRCIFMKSIQ---DVRSDDEDYEEEEEEEEEEA 356
Y F N LM+LQ+LH++W IL+ML FMK Q D+RSD EE + EEA
Sbjct: 301 GYYFFNGLLMLLQLLHVFWSCLILRMLYS--FMKKGQMEKDIRSD-----VEESDSSEEA 353
Query: 357 TKGKEMDCLKNG 368
+E LKNG
Sbjct: 354 AAAQEPLQLKNG 365
>gi|22218345 LAG1 homolog, ceramide synthase 5 [Homo sapiens]
Length = 392
Score = 305 bits (782), Expect = 3e-83
Identities = 151/346 (43%), Positives = 216/346 (62%), Gaps = 3/346 (0%)
Query: 8 WFWLERFWLPPTIKWSDLEDH-DGLVFVKPSHLYVTIPYAFLLLIIRRVFEKFVASPLAK 66
W W ERFWLP + W+DLE DG + + H+ P A + +R +FE+F+A P A
Sbjct: 15 WLWSERFWLPENVSWADLEGPADGYGYPRGRHILSVFPLAAGIFFVRLLFERFIAKPCAL 74
Query: 67 SFGIKET-VRKVTPNTVLENFFKHSTRQPLQTDIYGLAKKCNLTERQVERWFRSRRNQER 125
GI+++ + PN +LE F T+ P + + GL+K+ + R+++ WFR RRNQ++
Sbjct: 75 CIGIEDSGPYQAQPNAILEKVFISITKYPDKKRLEGLSKQLDWNVRKIQCWFRHRRNQDK 134
Query: 126 PSRLKKFQEACWRFAFYLMITVAGIAFLYDKPWLYDLWEVWNGYPKQPLLPSQYWYYILE 185
P L KF E+ WRF FYL I GI FL+ PW +D+ + W+ YP QPL Y YYI+E
Sbjct: 135 PPTLTKFCESMWRFTFYLCIFCYGIRFLWSSPWFWDIRQCWHNYPFQPLSSGLYHYYIME 194
Query: 186 MSFYWSLLFRLGFDVKRKDFLAHIIHHLAAISLMSFSWCANYIRSGTLVMIVHDVADIWL 245
++FYWSL+F D+KRKDFL +HHL I L+SFS+ N +R GTL+M +HDV+D L
Sbjct: 195 LAFYWSLMFSQFTDIKRKDFLIMFVHHLVTIGLISFSYINNMVRVGTLIMCLHDVSDFLL 254
Query: 246 ESAKMFSYAGWTQTCNTLFFIFSTIFFISRLIVFPFWILYCTLILPMYHLEPFFSYIFLN 305
E+AK+ +YA + + C+TLF IFS +F ++RL ++PFWIL TL + P+ S+ LN
Sbjct: 255 EAAKLANYAKYQRLCDTLFVIFSAVFMVTRLGIYPFWILNTTLFESWEIIGPYASWWLLN 314
Query: 306 LQLMILQVLHLYWGYYILKM-LNRCIFMKSIQDVRSDDEDYEEEEE 350
L+ LQ+LH+ W Y I ++ L I K +D RSD E EEE+
Sbjct: 315 GLLLTLQLLHVIWSYLIARIALKALIRGKVSKDDRSDVESSSEEED 360
>gi|45007002 longevity assurance homolog 6 [Homo sapiens]
Length = 384
Score = 298 bits (764), Expect = 4e-81
Identities = 145/347 (41%), Positives = 216/347 (62%), Gaps = 2/347 (0%)
Query: 8 WFWLERFWLPPTIKWSDLEDHDGLVFVKPSHLYVTIPYAFLLLIIRRVFEKFVASPLAKS 67
WFW ERFWLP + W+DL++ + F + LY+ P AF + ++R +FE+FVA P A +
Sbjct: 7 WFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIA 66
Query: 68 FGIKETVRKVTP-NTVLENFFKHSTRQPLQTDIYGLAKKCNLTERQVERWFRSRRNQERP 126
I+ ++ P N +LE F T+ P + + GL+K+ + R ++RWFR RRNQE+P
Sbjct: 67 LNIQANGPQIAPPNAILEKVFTAITKHPDEKRLEGLSKQLDWDVRSIQRWFRQRRNQEKP 126
Query: 127 SRLKKFQEACWRFAFYLMITVAGIAFLYDKPWLYDLWEVWNGYPKQPLLPSQYWYYILEM 186
S L +F E+ WRF+FYL + G+ FL PWL++ W YP QPL ++YYILE+
Sbjct: 127 STLTRFCESMWRFSFYLYVFTYGVRFLKKTPWLWNTRHCWYNYPYQPLTTDLHYYYILEL 186
Query: 187 SFYWSLLFRLGFDVKRKDFLAHIIHHLAAISLMSFSWCANYIRSGTLVMIVHDVADIWLE 246
SFYWSL+F D+KRKDF +HHL +I L++FS+ N R GTLV+ +HD AD LE
Sbjct: 187 SFYWSLMFSQFTDIKRKDFGIMFLHHLVSIFLITFSYVNNMARVGTLVLCLHDSADALLE 246
Query: 247 SAKMFSYAGWTQTCNTLFFIFSTIFFISRLIVFPFWILYCTLILPMYHLEPFFSYIFLNL 306
+AKM +YA + + C+ LF +F+ +F +RL +FP W+L TL + P+ S+ NL
Sbjct: 247 AAKMANYAKFQKMCDLLFVMFAVVFITTRLGIFPLWVLNTTLFESWEIVGPYPSWWVFNL 306
Query: 307 QLMILQVLHLYWGYYILKMLNRCIFM-KSIQDVRSDDEDYEEEEEEE 352
L+++Q L+ +W Y I+K+ + + K +D RSD E +EE+ E
Sbjct: 307 LLLLVQGLNCFWSYLIVKIACKAVSRGKVSKDDRSDIESSSDEEDSE 353
>gi|11641421 LAG1 homolog, ceramide synthase 1 isoform 1 [Homo
sapiens]
Length = 350
Score = 86.7 bits (213), Expect = 3e-17
Identities = 69/265 (26%), Positives = 113/265 (42%), Gaps = 32/265 (12%)
Query: 125 RPSRLKKFQEACWRFAFYL--------MITVAGIAFLYDKPWLYDLWEVWNGYPKQPLLP 176
+P K E+ W+F FYL ++ F +D P ++ W P+
Sbjct: 92 QPRDAAKMPESAWKFLFYLGSWSYSAYLLFGTDYPFFHDPPSVFYDWTPGMAVPRDIAAA 151
Query: 177 SQYWYYILEMSFYW-SLLFRLGFDVKRKDFLAHIIHHLAAISLMSFSWCANYIRSGTLVM 235
Y+L+ SFY S+ L D RKD + ++HH+ + L+ S+ Y G LV+
Sbjct: 152 -----YLLQGSFYGHSIYATLYMDTWRKDSVVMLLHHVVTLILIVSSYAFRYHNVGILVL 206
Query: 236 IVHDVADIWLESAKMFSY-----------AGWTQTCNTLFFIFSTIFFISRLIVFPFWIL 284
+HD++D+ LE K+ Y L F FS +F RL FP +L
Sbjct: 207 FLHDISDVQLEFTKLNIYFKSRGGSYHRLHALAADLGCLSFGFSWFWF--RLYWFPLKVL 264
Query: 285 YCTLILPMYHLEPFFSYIFLNLQLMILQVLHLYWGYYILKMLNRCIFMKSIQDVRSDDED 344
Y T + + Y F N L++L +++LYW YI+ + + + +++ D
Sbjct: 265 YATSHCSLRTVPDIPFYFFFNALLLLLTLMNLYWFLYIVAFAAK-VLTGQVHELK----D 319
Query: 345 YEEEEEEEEEEATKGKEMDCLKNGL 369
E + E + K L+NGL
Sbjct: 320 LREYDTAEAQSLKPSKAEKPLRNGL 344
>gi|38176296 LAG1 homolog, ceramide synthase 1 isoform 2 [Homo
sapiens]
Length = 337
Score = 83.6 bits (205), Expect = 3e-16
Identities = 64/240 (26%), Positives = 105/240 (43%), Gaps = 29/240 (12%)
Query: 125 RPSRLKKFQEACWRFAFYL--------MITVAGIAFLYDKPWLYDLWEVWNGYPKQPLLP 176
+P K E+ W+F FYL ++ F +D P ++ W P+
Sbjct: 92 QPRDAAKMPESAWKFLFYLGSWSYSAYLLFGTDYPFFHDPPSVFYDWTPGMAVPRDIAAA 151
Query: 177 SQYWYYILEMSFYW-SLLFRLGFDVKRKDFLAHIIHHLAAISLMSFSWCANYIRSGTLVM 235
Y+L+ SFY S+ L D RKD + ++HH+ + L+ S+ Y G LV+
Sbjct: 152 -----YLLQGSFYGHSIYATLYMDTWRKDSVVMLLHHVVTLILIVSSYAFRYHNVGILVL 206
Query: 236 IVHDVADIWLESAKMFSY-----------AGWTQTCNTLFFIFSTIFFISRLIVFPFWIL 284
+HD++D+ LE K+ Y L F FS +F RL FP +L
Sbjct: 207 FLHDISDVQLEFTKLNIYFKSRGGSYHRLHALAADLGCLSFGFSWFWF--RLYWFPLKVL 264
Query: 285 YCTLILPMYHLEPFFSYIFLNLQLMILQVLHLYWGYYILKMLNRCIF--MKSIQDVRSDD 342
Y T + + Y F N L++L +++LYW YI+ + + + ++D+R D
Sbjct: 265 YATSHCSLRTVPDIPFYFFFNALLLLLTLMNLYWFLYIVAFAAKVLTGQVHELKDLREYD 324
>gi|7657655 translocation associated membrane protein 1 [Homo
sapiens]
Length = 374
Score = 45.4 bits (106), Expect = 8e-05
Identities = 31/167 (18%), Positives = 76/167 (45%), Gaps = 3/167 (1%)
Query: 119 SRRNQERPSRLKKFQEACWRFAFYLMITVAGIAFLYDKPWLYDLWEVWNGYPKQPLLPSQ 178
+RR ++ KF E+ AFYL V G L + ++ D +W YP +
Sbjct: 106 NRRMHFSKTKHSKFNESGQLSAFYLFACVWGTFILISENYISDPTILWRAYPHNLMTFQM 165
Query: 179 YWYYILEMSFYWSLLFRLGFD-VKRKDFLAHIIHHLAAISLMSFSWCANYIRSGTLVMIV 237
++YI +++++ L F K++D +++ + ++ ++ N G +++++
Sbjct: 166 KFFYISQLAYWLHAFPELYFQKTKKEDIPRQLVYIGLYLFHIAGAYLLNLNHLGLVLLVL 225
Query: 238 HDVADIWLESAKMFSYAGWTQTCNTLFFIFSTIFFISRLIVFPFWIL 284
H + +++F ++ + F +++ +F + RL+ +L
Sbjct: 226 HYFVEFLFHISRLFYFS--NEKYQKGFSLWAVLFVLGRLLTLILSVL 270
>gi|6912450 translocation-associated membrane protein 2 [Homo
sapiens]
Length = 370
Score = 39.7 bits (91), Expect = 0.005
Identities = 34/195 (17%), Positives = 84/195 (43%), Gaps = 9/195 (4%)
Query: 131 KFQEACWRFAFYLMITVAGIAFLYDKPWLYDLWEVWNGYPKQPLLPSQYWYYILEMSFYW 190
KF E+ F+ + + + +L + +W YP L ++Y+ +++++
Sbjct: 113 KFNESGQLVVFHFTSVIWCFYVVVTEGYLTNPRSLWEDYPHVHLPFQVKFFYLCQLAYWL 172
Query: 191 SLLFRLGFDVKRKDFLAHIIHHLAAISL-MSFSWCANYIRSGTLVMIVHDVADIWLESAK 249
L L F RK+ + + ++ + ++ ++ N R G +++++ + +A+
Sbjct: 173 HALPELYFQKVRKEEIPRQLQYICLYLVHIAGAYLLNLSRLGLILLLLQYSTEFLFHTAR 232
Query: 250 MFSYAGWTQTCNTLFFIFSTIFFISRLIVFPFWILYCTLILPMYHLEPF------FSYIF 303
+F +A + LF ++ +F ++RL + +L L + F F+ +F
Sbjct: 233 LFYFA--DENNEKLFSAWAAVFGVTRLFILTLAVLAIGFGLARMENQAFDPEKGNFNTLF 290
Query: 304 LNLQLMILQVLHLYW 318
L +++L W
Sbjct: 291 CRLCVLLLVCAAQAW 305
>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
Length = 1184
Score = 37.7 bits (86), Expect = 0.017
Identities = 15/29 (51%), Positives = 22/29 (75%)
Query: 336 QDVRSDDEDYEEEEEEEEEEATKGKEMDC 364
+DV ++E+ EEEEEEEEEE + +M+C
Sbjct: 147 EDVEDEEEEEEEEEEEEEEEENEDHQMNC 175
Score = 30.8 bits (68), Expect = 2.1
Identities = 14/26 (53%), Positives = 18/26 (69%)
Query: 336 QDVRSDDEDYEEEEEEEEEEATKGKE 361
+D D ED E+EEEEEEEE + +E
Sbjct: 140 EDDDEDGEDVEDEEEEEEEEEEEEEE 165
>gi|56711320 hypothetical protein LOC145407 [Homo sapiens]
Length = 774
Score = 37.0 bits (84), Expect = 0.030
Identities = 17/40 (42%), Positives = 25/40 (62%)
Query: 336 QDVRSDDEDYEEEEEEEEEEATKGKEMDCLKNGLRAERHL 375
+D +DE+ E+EEEE+EEE + K+ D L GL + L
Sbjct: 614 EDEDEEDEEDEDEEEEDEEEDEEDKDADSLDEGLDGDTEL 653
>gi|20336305 B-cell CLL/lymphoma 11A isoform 1 [Homo sapiens]
Length = 835
Score = 36.6 bits (83), Expect = 0.039
Identities = 19/40 (47%), Positives = 25/40 (62%), Gaps = 1/40 (2%)
Query: 336 QDVRSDDEDYEEEEEEEEEEATKGKEMDC-LKNGLRAERH 374
++ DDE+ EEEEEEEEEE T+ + +D L A RH
Sbjct: 485 EEEEEDDEEEEEEEEEEEEELTESERVDYGFGLSLEAARH 524
>gi|20336307 B-cell CLL/lymphoma 11A isoform 2 [Homo sapiens]
Length = 773
Score = 36.6 bits (83), Expect = 0.039
Identities = 19/40 (47%), Positives = 25/40 (62%), Gaps = 1/40 (2%)
Query: 336 QDVRSDDEDYEEEEEEEEEEATKGKEMDC-LKNGLRAERH 374
++ DDE+ EEEEEEEEEE T+ + +D L A RH
Sbjct: 485 EEEEEDDEEEEEEEEEEEEELTESERVDYGFGLSLEAARH 524
>gi|198041755 pre-B-cell leukemia homeobox 3 isoform 2 [Homo
sapiens]
Length = 359
Score = 36.6 bits (83), Expect = 0.039
Identities = 23/66 (34%), Positives = 34/66 (51%), Gaps = 2/66 (3%)
Query: 84 ENFFKH-STRQPLQTDIYGLAKKCNLTERQVERWFRSRRNQERPSRLKKFQEACWRFAFY 142
E F+ H S P + LAKKC++T QV WF ++R + + + KFQE +A
Sbjct: 177 EYFYSHLSNPYPSEEAKEELAKKCSITVSQVSNWFGNKRIRYK-KNIGKFQEEANLYAAK 235
Query: 143 LMITVA 148
+T A
Sbjct: 236 TAVTAA 241
>gi|5453852 pre-B-cell leukemia homeobox 3 isoform 1 [Homo sapiens]
Length = 434
Score = 36.6 bits (83), Expect = 0.039
Identities = 23/66 (34%), Positives = 34/66 (51%), Gaps = 2/66 (3%)
Query: 84 ENFFKH-STRQPLQTDIYGLAKKCNLTERQVERWFRSRRNQERPSRLKKFQEACWRFAFY 142
E F+ H S P + LAKKC++T QV WF ++R + + + KFQE +A
Sbjct: 252 EYFYSHLSNPYPSEEAKEELAKKCSITVSQVSNWFGNKRIRYK-KNIGKFQEEANLYAAK 310
Query: 143 LMITVA 148
+T A
Sbjct: 311 TAVTAA 316
>gi|4503257 death-domain associated protein isoform a [Homo sapiens]
Length = 740
Score = 36.2 bits (82), Expect = 0.051
Identities = 17/31 (54%), Positives = 22/31 (70%)
Query: 336 QDVRSDDEDYEEEEEEEEEEATKGKEMDCLK 366
+D DE+ EEEEEEEEEEAT +E + L+
Sbjct: 438 EDDEESDEEEEEEEEEEEEEATDSEEEEDLE 468
>gi|215422388 death-domain associated protein isoform a [Homo
sapiens]
Length = 740
Score = 36.2 bits (82), Expect = 0.051
Identities = 17/31 (54%), Positives = 22/31 (70%)
Query: 336 QDVRSDDEDYEEEEEEEEEEATKGKEMDCLK 366
+D DE+ EEEEEEEEEEAT +E + L+
Sbjct: 438 EDDEESDEEEEEEEEEEEEEATDSEEEEDLE 468
>gi|215422366 death-domain associated protein isoform b [Homo
sapiens]
Length = 752
Score = 36.2 bits (82), Expect = 0.051
Identities = 17/31 (54%), Positives = 22/31 (70%)
Query: 336 QDVRSDDEDYEEEEEEEEEEATKGKEMDCLK 366
+D DE+ EEEEEEEEEEAT +E + L+
Sbjct: 450 EDDEESDEEEEEEEEEEEEEATDSEEEEDLE 480
>gi|55741655 anoctamin 8 [Homo sapiens]
Length = 1232
Score = 35.8 bits (81), Expect = 0.066
Identities = 16/33 (48%), Positives = 24/33 (72%)
Query: 341 DDEDYEEEEEEEEEEATKGKEMDCLKNGLRAER 373
D++D EEE+EEEEE+ +G+E L GLR ++
Sbjct: 584 DEDDEEEEDEEEEEDEEEGEEGGLLDCGLRLKK 616
>gi|4505623 pre-B-cell leukemia homeobox 1 [Homo sapiens]
Length = 430
Score = 35.8 bits (81), Expect = 0.066
Identities = 22/69 (31%), Positives = 34/69 (49%), Gaps = 2/69 (2%)
Query: 84 ENFFKH-STRQPLQTDIYGLAKKCNLTERQVERWFRSRRNQERPSRLKKFQEACWRFAFY 142
E F+ H S P + LAKKC +T QV WF ++R + + + KFQE +A
Sbjct: 250 EYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYK-KNIGKFQEEANIYAAK 308
Query: 143 LMITVAGIA 151
+T ++
Sbjct: 309 TAVTATNVS 317
>gi|145580602 translocation associated membrane protein 1-like 1
[Homo sapiens]
Length = 369
Score = 35.8 bits (81), Expect = 0.066
Identities = 31/163 (19%), Positives = 66/163 (40%), Gaps = 9/163 (5%)
Query: 119 SRRNQERPSRLKKFQEACWRFAFYLMITVAGIAFLYDKPWLYDLWEVWNGYPKQPLLPSQ 178
++R Q ++ KF E+ FY + G L + L D +W P +
Sbjct: 106 NKRMQFTKAKQNKFNESGQFSVFYFFSCIWGTFILISENCLSDPTLIWKARPHSMMTFQM 165
Query: 179 YWYYILEMSFYWSLLFRLGFDVKRKDFLAHIIHHLAAISLMSFSWCANYI----RSGTLV 234
++YI ++++++ L F +K I L I L F Y+ G L+
Sbjct: 166 KFFYISQLAYWFHAFPELYFQKTKKQ---DIPRQLVYIGLHLFHITGAYLLYLNHLGLLL 222
Query: 235 MIVHDVADIWLESAKMFSYAGWTQTCNTLFFIFSTIFFISRLI 277
+++H ++ +F ++ + +++ +F + RL+
Sbjct: 223 LVLHYFVELLSHMCGLFYFS--DEKYQKGISLWAIVFILGRLV 263
>gi|51477718 TATA box binding protein-associated factor, RNA
polymerase II, Q [Homo sapiens]
Length = 462
Score = 35.0 bits (79), Expect = 0.11
Identities = 20/49 (40%), Positives = 31/49 (63%), Gaps = 6/49 (12%)
Query: 337 DVRSDDEDYEEEEEEEEEEATKGKEMDC----LKNGLRAERHLIPNGQH 381
D DDED +E+E+E+E+E + +E DC L+ L+AE I +GQ+
Sbjct: 335 DEDEDDEDEDEDEDEDEDEDKEEEEEDCSEEYLERQLQAE--FIESGQY 381
>gi|121114296 caudal type homeobox 1 [Homo sapiens]
Length = 265
Score = 35.0 bits (79), Expect = 0.11
Identities = 17/33 (51%), Positives = 22/33 (66%)
Query: 102 LAKKCNLTERQVERWFRSRRNQERPSRLKKFQE 134
LA LTERQV+ WF++RR +ER KK Q+
Sbjct: 187 LAANLGLTERQVKIWFQNRRAKERKVNKKKQQQ 219
>gi|4759128 solute carrier family 24 (sodium/potassium/calcium
exchanger), member 1 [Homo sapiens]
Length = 1099
Score = 35.0 bits (79), Expect = 0.11
Identities = 15/26 (57%), Positives = 19/26 (73%)
Query: 336 QDVRSDDEDYEEEEEEEEEEATKGKE 361
Q+ ++E+ EEEEEEEEEE KG E
Sbjct: 869 QEEEEEEEEQEEEEEEEEEEEEKGNE 894
Score = 28.9 bits (63), Expect = 8.1
Identities = 12/25 (48%), Positives = 18/25 (72%)
Query: 337 DVRSDDEDYEEEEEEEEEEATKGKE 361
D ++E+ EE+EEEEEEE + +E
Sbjct: 858 DSEEEEEEEEEQEEEEEEEEQEEEE 882
>gi|4759208 TAO kinase 2 isoform 1 [Homo sapiens]
Length = 1049
Score = 34.7 bits (78), Expect = 0.15
Identities = 14/29 (48%), Positives = 22/29 (75%)
Query: 340 SDDEDYEEEEEEEEEEATKGKEMDCLKNG 368
+++E+ EEEEEEEEEE + +EM ++ G
Sbjct: 377 NEEEEEEEEEEEEEEEGPEAREMAMMQEG 405
>gi|45505130 TAO kinase 2 isoform 2 [Homo sapiens]
Length = 1235
Score = 34.7 bits (78), Expect = 0.15
Identities = 14/29 (48%), Positives = 22/29 (75%)
Query: 340 SDDEDYEEEEEEEEEEATKGKEMDCLKNG 368
+++E+ EEEEEEEEEE + +EM ++ G
Sbjct: 377 NEEEEEEEEEEEEEEEGPEAREMAMMQEG 405
>gi|27436887 pre-B-cell leukemia homeobox 2 [Homo sapiens]
Length = 430
Score = 34.7 bits (78), Expect = 0.15
Identities = 22/65 (33%), Positives = 33/65 (50%), Gaps = 2/65 (3%)
Query: 84 ENFFKH-STRQPLQTDIYGLAKKCNLTERQVERWFRSRRNQERPSRLKKFQEACWRFAFY 142
E F+ H S P + LAKKC +T QV WF ++R + + + KFQE +A
Sbjct: 261 EYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYK-KNIGKFQEEANIYAVK 319
Query: 143 LMITV 147
++V
Sbjct: 320 TAVSV 324
>gi|169636435 caudal type homeobox 2 [Homo sapiens]
Length = 313
Score = 34.3 bits (77), Expect = 0.19
Identities = 16/33 (48%), Positives = 22/33 (66%)
Query: 102 LAKKCNLTERQVERWFRSRRNQERPSRLKKFQE 134
LA L+ERQV+ WF++RR +ER KK Q+
Sbjct: 219 LAATLGLSERQVKIWFQNRRAKERKINKKKLQQ 251
>gi|48255900 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a2 isoform a [Homo sapiens]
Length = 1590
Score = 34.3 bits (77), Expect = 0.19
Identities = 18/52 (34%), Positives = 29/52 (55%)
Query: 305 NLQLMILQVLHLYWGYYILKMLNRCIFMKSIQDVRSDDEDYEEEEEEEEEEA 356
N Q L+ +Y +L+ + + K ++ S+DE EEEEEE+EEE+
Sbjct: 1477 NAQTFNLEGSQIYEDSIVLQSVFKSARQKIAKEEESEDESNEEEEEEDEEES 1528
Score = 28.9 bits (63), Expect = 8.1
Identities = 12/25 (48%), Positives = 15/25 (60%)
Query: 337 DVRSDDEDYEEEEEEEEEEATKGKE 361
D D DYEEE+EEEE + +E
Sbjct: 634 DSEESDSDYEEEDEEEESSRQETEE 658
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.329 0.142 0.479
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,731,896
Number of Sequences: 37866
Number of extensions: 648704
Number of successful extensions: 12914
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 216
Number of HSP's successfully gapped in prelim test: 39
Number of HSP's that attempted gapping in prelim test: 9487
Number of HSP's gapped (non-prelim): 2174
length of query: 383
length of database: 18,247,518
effective HSP length: 104
effective length of query: 279
effective length of database: 14,309,454
effective search space: 3992337666
effective search space used: 3992337666
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.