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Search of human proteins with 239741047
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239741047 PREDICTED: PRAME family member 25-like [Homo
sapiens]
(474 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239741047 PREDICTED: PRAME family member 25-like [Homo sapiens] 969 0.0
gi|194306638 PRAME family member 3 [Homo sapiens] 696 0.0
gi|154800493 PRAME family member 22 [Homo sapiens] 695 0.0
gi|148356236 PRAME family member 15 [Homo sapiens] 675 0.0
gi|61102721 PRAME family member 9 [Homo sapiens] 675 0.0
gi|59958373 PRAME family member 4 [Homo sapiens] 667 0.0
gi|153791443 PRAME family member 18 [Homo sapiens] 664 0.0
gi|239741043 PREDICTED: PRAME family member 11 [Homo sapiens] 661 0.0
gi|61696142 PRAME family member 5 [Homo sapiens] 660 0.0
gi|194306635 PRAME family member 19 [Homo sapiens] 660 0.0
gi|58219004 PRAME family member 6 [Homo sapiens] 660 0.0
gi|239741045 PREDICTED: PRAME family member 23 [Homo sapiens] 657 0.0
gi|153792112 PRAME family member 20 [Homo sapiens] 626 e-179
gi|153945800 PRAME family member 21 [Homo sapiens] 626 e-179
gi|226437621 PRAME family member 11 [Homo sapiens] 606 e-173
gi|88942379 PREDICTED: PRAME family member [Homo sapiens] 566 e-161
gi|124249372 PRAME family member 12 [Homo sapiens] 550 e-157
gi|239741053 PREDICTED: similar to Putative PRAME family member ... 523 e-148
gi|59676587 PRAME family member 8 [Homo sapiens] 523 e-148
gi|59676593 PRAME family member 7 [Homo sapiens] 522 e-148
gi|194018546 PRAME family member 10 [Homo sapiens] 504 e-143
gi|157426839 PRAME family member 17 [Homo sapiens] 493 e-139
gi|113865933 PRAME family member 16 [Homo sapiens] 491 e-139
gi|239741051 PREDICTED: similar to PRAME family member 10 [Homo ... 471 e-133
gi|239741055 PREDICTED: similar to PRAME family member 10 [Homo ... 471 e-133
gi|12738831 PRAME family member 1 [Homo sapiens] 469 e-132
gi|66954681 PRAME family member 13 [Homo sapiens] 469 e-132
gi|12738834 PRAME family member 2 [Homo sapiens] 459 e-129
gi|153792140 PRAME family member 14 [Homo sapiens] 424 e-118
gi|46249373 preferentially expressed antigen in melanoma [Homo s... 398 e-111
>gi|239741047 PREDICTED: PRAME family member 25-like [Homo sapiens]
Length = 474
Score = 969 bits (2504), Expect = 0.0
Identities = 474/474 (100%), Positives = 474/474 (100%)
Query: 1 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 60
MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP
Sbjct: 1 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 60
Query: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 120
FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR
Sbjct: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 120
Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 180
PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 180
Query: 181 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSPYLSQMRNLRKLFIS 240
CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSPYLSQMRNLRKLFIS
Sbjct: 181 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSPYLSQMRNLRKLFIS 240
Query: 241 DGCRYLLSSDSQEQIAPFTTQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLTIT 300
DGCRYLLSSDSQEQIAPFTTQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLTIT
Sbjct: 241 DGCRYLLSSDSQEQIAPFTTQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLTIT 300
Query: 301 NCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDCGI 360
NCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDCGI
Sbjct: 301 NCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDCGI 360
Query: 361 IDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCLELYPAPRESYGA 420
IDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCLELYPAPRESYGA
Sbjct: 361 IDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCLELYPAPRESYGA 420
Query: 421 DGTLCWSRFTQIRAELMKRVRDLRHPKRILFGTDYCPDCGNRSFYDLEADQYCC 474
DGTLCWSRFTQIRAELMKRVRDLRHPKRILFGTDYCPDCGNRSFYDLEADQYCC
Sbjct: 421 DGTLCWSRFTQIRAELMKRVRDLRHPKRILFGTDYCPDCGNRSFYDLEADQYCC 474
>gi|194306638 PRAME family member 3 [Homo sapiens]
Length = 481
Score = 696 bits (1795), Expect = 0.0
Identities = 360/469 (76%), Positives = 387/469 (82%), Gaps = 1/469 (0%)
Query: 1 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 60
MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP
Sbjct: 3 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
Query: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 120
FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR
Sbjct: 63 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 122
Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 180
PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL
Sbjct: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
Query: 181 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSPYLSQMRNLRKLFIS 240
CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEF YLSQMRNLRKLFIS
Sbjct: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFIRYLSQMRNLRKLFIS 242
Query: 241 DGCRYLLSSDSQEQ-IAPFTTQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLTI 299
DGCRYLLSSDSQEQ +A F++ L+L LQ LY+ V F GHLDQL+ CL++ L+ L +
Sbjct: 243 DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETLAL 302
Query: 300 TNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDCG 359
T L + DLK L + PS+SQLK L+LS L L PL+ LLEKVAATL+ L L DCG
Sbjct: 303 TYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDCG 362
Query: 360 IIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCLELYPAPRESYG 419
I DS++ ILPALS C L TF F GN SM L++LL HT L NL LE YPAPRES
Sbjct: 363 IRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 422
Query: 420 ADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGTDYCPDCGNRSFYDLE 468
G + T ++AELM+ +R++R PKRI FG CP CG LE
Sbjct: 423 DRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLE 471
>gi|154800493 PRAME family member 22 [Homo sapiens]
Length = 481
Score = 695 bits (1793), Expect = 0.0
Identities = 360/469 (76%), Positives = 387/469 (82%), Gaps = 1/469 (0%)
Query: 1 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 60
MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP
Sbjct: 3 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
Query: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 120
FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRR KLQVLELRDVDENFWTIWSGAR
Sbjct: 63 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122
Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 180
PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL
Sbjct: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
Query: 181 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSPYLSQMRNLRKLFIS 240
CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFS YLSQMRNLRKLFIS
Sbjct: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSRYLSQMRNLRKLFIS 242
Query: 241 DGCRYLLSSDSQEQ-IAPFTTQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLTI 299
DGCRYLLSSDSQEQ +A F++ L+L LQ LY+ V F GHLDQL+ CL++ L+ L +
Sbjct: 243 DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETLAL 302
Query: 300 TNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDCG 359
T L + DLK L + PS+SQLK L+LS L L PL+ LLEKVAATL+ L L DCG
Sbjct: 303 TYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDCG 362
Query: 360 IIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCLELYPAPRESYG 419
I DS++ ILPALS C L TF F GN SM L++LL HT L NL LE YPAPRES
Sbjct: 363 IRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 422
Query: 420 ADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGTDYCPDCGNRSFYDLE 468
G + T ++AELM+ +R++R PKRI FG CP CG LE
Sbjct: 423 DRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLE 471
>gi|148356236 PRAME family member 15 [Homo sapiens]
Length = 478
Score = 675 bits (1742), Expect = 0.0
Identities = 345/477 (72%), Positives = 387/477 (81%), Gaps = 4/477 (0%)
Query: 1 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 60
MS++ P RLLELAG+SLL DQALA+S L+ELP ELFPPLF+EAF+ RRCE LK+MVQAWP
Sbjct: 3 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 62
Query: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 120
F LPL L+K P LE V+DG+D LL Q VRPRR KLQVL+L+DV ENFW +WS A
Sbjct: 63 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 180
C A ++ V+DCPR +QPL VF+++ LK + +DE L++ WV+ R+ +HL
Sbjct: 123 AHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLLHL 182
Query: 181 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIV-EFSPYLSQMRNLRKLFI 239
CC K+ M N R+IL+ V D IQ +E+ N W I+ +F+PYL MRNL+KL +
Sbjct: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLVL 241
Query: 240 S--DGCRYLLSSDSQEQIAPFTTQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVL 297
S D RY+ +E + FTTQFLKL CLQKLYMNSVSFLEGHLDQLLSCLKTSLKVL
Sbjct: 242 SHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVL 301
Query: 298 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 357
TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD
Sbjct: 302 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 361
Query: 358 CGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCLELYPAPRES 417
CGIIDSQVNAILPALSRCFELNTFSFCGNPI MATLENLLSHTIILKNLC+ELYPAPRES
Sbjct: 362 CGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRES 421
Query: 418 YGADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGTDYCPDCGNRSFYDLEADQYCC 474
YGADGTLCWSRF QIRAELM RVRDLRHPKRILF TDYCPDCGNRSFYDLEADQYCC
Sbjct: 422 YGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
>gi|61102721 PRAME family member 9 [Homo sapiens]
Length = 478
Score = 675 bits (1742), Expect = 0.0
Identities = 345/477 (72%), Positives = 387/477 (81%), Gaps = 4/477 (0%)
Query: 1 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 60
MS++ P RLLELAG+SLL DQALA+S L+ELP ELFPPLF+EAF+ RRCE LK+MVQAWP
Sbjct: 3 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 62
Query: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 120
F LPL L+K P LE V+DG+D LL Q VRPRR KLQVL+L+DV ENFW +WS A
Sbjct: 63 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 180
C A ++ V+DCPR +QPL VF+++ LK + +DE L++ WV+ R+ +HL
Sbjct: 123 AHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLLHL 182
Query: 181 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIV-EFSPYLSQMRNLRKLFI 239
CC K+ M N R+IL+ V D IQ +E+ N W I+ +F+PYL MRNL+KL +
Sbjct: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLVL 241
Query: 240 S--DGCRYLLSSDSQEQIAPFTTQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVL 297
S D RY+ +E + FTTQFLKL CLQKLYMNSVSFLEGHLDQLLSCLKTSLKVL
Sbjct: 242 SHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVL 301
Query: 298 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 357
TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD
Sbjct: 302 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 361
Query: 358 CGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCLELYPAPRES 417
CGIIDSQVNAILPALSRCFELNTFSFCGNPI MATLENLLSHTIILKNLC+ELYPAPRES
Sbjct: 362 CGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRES 421
Query: 418 YGADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGTDYCPDCGNRSFYDLEADQYCC 474
YGADGTLCWSRF QIRAELM RVRDLRHPKRILF TDYCPDCGNRSFYDLEADQYCC
Sbjct: 422 YGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
>gi|59958373 PRAME family member 4 [Homo sapiens]
Length = 478
Score = 667 bits (1721), Expect = 0.0
Identities = 343/477 (71%), Positives = 383/477 (80%), Gaps = 4/477 (0%)
Query: 1 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 60
MS+ P RLLELAG+SLL DQALA+S L+ELP ELFPPLF+EAF+ RRCE LK+MVQ+WP
Sbjct: 3 MSIWTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQSWP 62
Query: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 120
F LPL L+K P LE V+DG+D LL VRPRR KLQVL+L+DV ENFW +WS A
Sbjct: 63 FRRLPLRPLIKMPCLEAFQAVLDGLDALLNLGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 180
C A ++ VEDCPR +QPL VF+++ LK + +DE L+ WV+ R+ +HL
Sbjct: 123 AHGCFLNAKRNKKPVEDCPRMRGRQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 182
Query: 181 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIV-EFSPYLSQMRNLRKLFI 239
CC K+ M N R+IL+ V D IQ +E+ N W I+ +F+PYL MRNL+KL +
Sbjct: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLIL 241
Query: 240 S--DGCRYLLSSDSQEQIAPFTTQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVL 297
S D RY+ +E + FTTQFLKL CLQKLYMNSVSFLEGHLDQLLSCLKTSLK L
Sbjct: 242 SHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKFL 301
Query: 298 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 357
TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD
Sbjct: 302 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 361
Query: 358 CGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCLELYPAPRES 417
CGIIDSQVNAILPALSRCFELNTFSFCGNPI MATLENLLSHTIILKNLC+ELYPAPRES
Sbjct: 362 CGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRES 421
Query: 418 YGADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGTDYCPDCGNRSFYDLEADQYCC 474
YGADGTLCWSRF QIRAELM RVRDLRHPKRILF TDYCPDCGNRSFYDLEADQYCC
Sbjct: 422 YGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
>gi|153791443 PRAME family member 18 [Homo sapiens]
Length = 479
Score = 664 bits (1712), Expect = 0.0
Identities = 345/469 (73%), Positives = 377/469 (80%), Gaps = 1/469 (0%)
Query: 1 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 60
MS QAPRRLLELAGQSLL DQALAIS+LDELPRELFP LFVEAFTSRRCEVLKVMVQAWP
Sbjct: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
Query: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 120
FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRR KLQVLE+RDVDENFWTIWSGAR
Sbjct: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 180
PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEK +DEDLSFFSGWVQHRR SVHL
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
Query: 181 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSPYLSQMRNLRKLFIS 240
CCTKVVNYSM+ILNFRNILETVYPDSIQVLEIWNMCWPCM+ E S YLSQM+NLRKLFIS
Sbjct: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS 240
Query: 241 DGCRYLLSSDSQEQ-IAPFTTQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLTI 299
DGC YL S +SQ Q +A F++ FL+L LQ LYM + F EG+LDQL+ CLK+ L+ L +
Sbjct: 241 DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL 300
Query: 300 TNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDCG 359
T L E DLK L PS+SQLK L+LS L L PL+ LLEKVAATL+ L L DCG
Sbjct: 301 TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG 360
Query: 360 IIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCLELYPAPRESYG 419
I DS++ ILPALSRC L TF F GN SM L++LL HT L NL LE YPAPRES
Sbjct: 361 IGDSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 420
Query: 420 ADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGTDYCPDCGNRSFYDLE 468
G + T ++AELM+ +R++R P RI FG CP CG LE
Sbjct: 421 NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLE 469
>gi|239741043 PREDICTED: PRAME family member 11 [Homo sapiens]
Length = 513
Score = 661 bits (1705), Expect = 0.0
Identities = 341/477 (71%), Positives = 383/477 (80%), Gaps = 4/477 (0%)
Query: 1 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 60
MS++ P RLLEL G+SLL DQALA+S L+ELP ELFPPLF+EAF+ RRCE LK+MVQAWP
Sbjct: 38 MSIRIPPRLLELXGRSLLRDQALAVSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 97
Query: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 120
F LPL L+K P LE V+DG+D LL Q VRPRR KLQVL+L+DV ENFW +WS A
Sbjct: 98 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 157
Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 180
C A + V+DCPR E+QPL VF+++ LK + +DE L+ WV+ RR +HL
Sbjct: 158 AHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTLDEYLTCLLLWVKQRRDLLHL 217
Query: 181 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIV-EFSPYLSQMRNLRKLFI 239
CC K+ M N R+IL+ V D IQ +E+ N W I+ +F+PYL +RNL+KL +
Sbjct: 218 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWILPILTQFTPYLGHLRNLQKLVL 276
Query: 240 S--DGCRYLLSSDSQEQIAPFTTQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVL 297
S D RY+ +E + FTTQFLKL CLQKLYMNSVSFLEGHLDQLLSCLKTSLKVL
Sbjct: 277 SHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVL 336
Query: 298 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 357
TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD
Sbjct: 337 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 396
Query: 358 CGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCLELYPAPRES 417
CGIIDSQVNAILPALSRCFELNTFSFCGNPI MATLENLLSHTIILKNLCLELYPAP+ES
Sbjct: 397 CGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCLELYPAPQES 456
Query: 418 YGADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGTDYCPDCGNRSFYDLEADQYCC 474
YGADGTLCWSRF QIRAELMK+VR LRHPKRILF TD CPD G+RSFYDLEADQYCC
Sbjct: 457 YGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPDHGDRSFYDLEADQYCC 513
>gi|61696142 PRAME family member 5 [Homo sapiens]
Length = 476
Score = 660 bits (1704), Expect = 0.0
Identities = 342/477 (71%), Positives = 383/477 (80%), Gaps = 4/477 (0%)
Query: 1 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 60
MS++ P RLLELAG+SLL DQALA+S L+ELP ELFPPLF+EAF+ RRCE LK+MVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
Query: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 120
F LPL L+K P LE V+DG+D LL Q V PRR KLQVL+L+DV ENFW +WS A
Sbjct: 61 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 180
C A ++ V+DCPR +QPL VF+++ LK + +DE L+ WV+ R+ +HL
Sbjct: 121 AHGCFLNAKRNKKPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
Query: 181 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIV-EFSPYLSQMRNLRKLFI 239
CC K+ M N R+IL+ V D IQ +E+ N W I+ +F+PYL MRNL+KL +
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLVL 239
Query: 240 S--DGCRYLLSSDSQEQIAPFTTQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVL 297
S D RY+ +E + FTTQFLKL CLQKL MNSVSFLEGHLDQLLSCLKTSLKVL
Sbjct: 240 SHMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVL 299
Query: 298 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 357
TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD
Sbjct: 300 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 359
Query: 358 CGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCLELYPAPRES 417
CGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLC+ELYPAPRES
Sbjct: 360 CGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRES 419
Query: 418 YGADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGTDYCPDCGNRSFYDLEADQYCC 474
Y ADGTLCWSRF QIRAELMKRVRDLRHPKRILF TD CPDCGNRSFYDLEADQ CC
Sbjct: 420 YDADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQCCC 476
>gi|194306635 PRAME family member 19 [Homo sapiens]
Length = 479
Score = 660 bits (1703), Expect = 0.0
Identities = 344/469 (73%), Positives = 376/469 (80%), Gaps = 1/469 (0%)
Query: 1 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 60
MS QAPRRLLELAGQSLL DQALAIS+LDELPRELFP LFVEAFTSRRCEVLKVMVQAWP
Sbjct: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
Query: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 120
FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRR KLQVLE+RDVDENFWTIWSGAR
Sbjct: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 180
PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEK +DEDLSFFSGWVQHRR SVHL
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
Query: 181 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSPYLSQMRNLRKLFIS 240
CCTKVVNYSM+ILNFRNILETVYPDSIQVLEIWNMCWPCM+ E S YLSQM+NLRKLFIS
Sbjct: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS 240
Query: 241 DGCRYLLSSDSQEQ-IAPFTTQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLTI 299
DGC YL S +SQ Q +A F++ FL+L LQ LYM + F EG+LDQL+ CLK+ L+ L +
Sbjct: 241 DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL 300
Query: 300 TNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDCG 359
T L E DLK L PS+SQLK L+LS L L PL+ LLEKVAATL+ L L DCG
Sbjct: 301 TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG 360
Query: 360 IIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCLELYPAPRESYG 419
I S++ ILPALSRC L TF F GN SM L++LL HT L NL LE YPAPRES
Sbjct: 361 IGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 420
Query: 420 ADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGTDYCPDCGNRSFYDLE 468
G + T ++AELM+ +R++R P RI FG CP CG LE
Sbjct: 421 NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLE 469
>gi|58219004 PRAME family member 6 [Homo sapiens]
Length = 476
Score = 660 bits (1703), Expect = 0.0
Identities = 342/477 (71%), Positives = 382/477 (80%), Gaps = 4/477 (0%)
Query: 1 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 60
MS++ P RLLELAG+SLL DQALA+S L+ELP ELFPPLF+EAF+ RRCE LK+MVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
Query: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 120
F LPL L+K P LE V+DG+D LL Q V PRR KLQVL+L+DV ENFW +WS A
Sbjct: 61 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 180
C A + V+DCPR +QPL VF+++ LK + +DE L+ WV+ R+ +HL
Sbjct: 121 ARGCFLNAKRNKTPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
Query: 181 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIV-EFSPYLSQMRNLRKLFI 239
CC K+ M N R+IL+ V D IQ +E+ N W I+ +F+PYL MRNL+KL +
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLVL 239
Query: 240 S--DGCRYLLSSDSQEQIAPFTTQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVL 297
S D RY+ +E + FTTQFLKL CLQKL MNSVSFLEGHLDQLLSCLKTSLKVL
Sbjct: 240 SHMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVL 299
Query: 298 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 357
TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD
Sbjct: 300 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 359
Query: 358 CGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCLELYPAPRES 417
CGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLC+ELYPAPRES
Sbjct: 360 CGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRES 419
Query: 418 YGADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGTDYCPDCGNRSFYDLEADQYCC 474
Y ADGTLCWSRF QIRAELMKRVRDLRHPKRILF TD CPDCGNRSFYDLEADQ CC
Sbjct: 420 YDADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQCCC 476
>gi|239741045 PREDICTED: PRAME family member 23 [Homo sapiens]
Length = 476
Score = 657 bits (1695), Expect = 0.0
Identities = 341/477 (71%), Positives = 382/477 (80%), Gaps = 4/477 (0%)
Query: 1 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 60
MS++ P RLLELAG+SLL DQALA+S L+ELP ELFPPLF+EAF+ RRCE LK+MVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
Query: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 120
F LPL L+K P LE V+DG+D LL Q V PRR KLQVL+L+DV ENFW +WS A
Sbjct: 61 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 180
C A ++ V+DCPR +QPL VF+++ LK + +DE L+ WV+ R+ +HL
Sbjct: 121 AHGCFLNAKRNKKPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
Query: 181 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIV-EFSPYLSQMRNLRKLFI 239
CC K+ M N R+IL+ V D IQ +E+ N W I+ +F+PYL MRNL+KL +
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLVL 239
Query: 240 S--DGCRYLLSSDSQEQIAPFTTQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVL 297
S D RY+ +E + FTTQFLKL CLQKL MNSVSFLEGHLDQLLSCLKTSLKVL
Sbjct: 240 SHMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVL 299
Query: 298 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 357
TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD
Sbjct: 300 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 359
Query: 358 CGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCLELYPAPRES 417
CGIIDSQVNAILPALS CFELNTFSFCGNPISMATLENLLSHTIILKNLC+ELYPAPRES
Sbjct: 360 CGIIDSQVNAILPALSCCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRES 419
Query: 418 YGADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGTDYCPDCGNRSFYDLEADQYCC 474
Y ADGTLCWSRF QIRAELMKRVRDLRHPKRILF TD CPDCGNRSFYDLEADQ CC
Sbjct: 420 YDADGTLCWSRFPQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQCCC 476
>gi|153792112 PRAME family member 20 [Homo sapiens]
Length = 475
Score = 626 bits (1614), Expect = e-179
Identities = 322/476 (67%), Positives = 366/476 (76%), Gaps = 3/476 (0%)
Query: 1 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 60
MS++ P RLLELAG+SLL D+ALAIS L+ELP ELFPPLF+EAF+ R CE LK+MVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60
Query: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 120
F LPLGSLMK P E V+DG+D LL +VR RR KLQVL+L+DV ENFW +WS A
Sbjct: 61 FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120
Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 180
C P AM R+ V+DCPR +QPL VF+D+CLK + +DE + WV+ R G VHL
Sbjct: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180
Query: 181 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPC-MIVEFSPYLSQMRNLRKLFI 239
CC K+ M N RNIL+TV D IQ +E+ N W ++ EF+PYL QMRNLRKL +
Sbjct: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEV-NCNWTLPVLAEFTPYLGQMRNLRKLVL 239
Query: 240 SD-GCRYLLSSDSQEQIAPFTTQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLT 298
SD RY+ +E + FTTQFLKL CLQKLYMNSVSFLEGHLDQ+LSCLKTSL +L
Sbjct: 240 SDIDSRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILA 299
Query: 299 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 358
ITNCVLLESDLKHLS+ PSI QLKTLDLSG RL N+SLVPLQ+LLEKVAATLEYLDLDDC
Sbjct: 300 ITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDC 359
Query: 359 GIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCLELYPAPRESY 418
GI+DSQVNAILPALSRCFEL TFSF GNPIS ATLENLL HTI L NLCLELYPAPRESY
Sbjct: 360 GIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESY 419
Query: 419 GADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGTDYCPDCGNRSFYDLEADQYCC 474
G +C SRF Q+ AELM RVR LR P+RILF TDYCP CGNRS YDLE D+ CC
Sbjct: 420 DVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRCCC 475
>gi|153945800 PRAME family member 21 [Homo sapiens]
Length = 475
Score = 626 bits (1614), Expect = e-179
Identities = 322/476 (67%), Positives = 366/476 (76%), Gaps = 3/476 (0%)
Query: 1 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 60
MS++ P RLLELAG+SLL D+ALAIS L+ELP ELFPPLF+EAF+ R CE LK+MVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60
Query: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 120
F LPLGSLMK P E V+DG+D LL +VR RR KLQVL+L+DV ENFW +WS A
Sbjct: 61 FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120
Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 180
C P AM R+ V+DCPR +QPL VF+D+CLK + +DE + WV+ R G VHL
Sbjct: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180
Query: 181 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPC-MIVEFSPYLSQMRNLRKLFI 239
CC K+ M N RNIL+TV D IQ +E+ N W ++ EF+PYL QMRNLRKL +
Sbjct: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEV-NCNWTLPVLAEFTPYLGQMRNLRKLVL 239
Query: 240 SD-GCRYLLSSDSQEQIAPFTTQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLT 298
SD RY+ +E + FTTQFLKL CLQKLYMNSVSFLEGHLDQ+LSCLKTSL +L
Sbjct: 240 SDIDSRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILA 299
Query: 299 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 358
ITNCVLLESDLKHLS+ PSI QLKTLDLSG RL N+SLVPLQ+LLEKVAATLEYLDLDDC
Sbjct: 300 ITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDC 359
Query: 359 GIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCLELYPAPRESY 418
GI+DSQVNAILPALSRCFEL TFSF GNPIS ATLENLL HTI L NLCLELYPAPRESY
Sbjct: 360 GIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESY 419
Query: 419 GADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGTDYCPDCGNRSFYDLEADQYCC 474
G +C SRF Q+ AELM RVR LR P+RILF TDYCP CGNRS YDLE D+ CC
Sbjct: 420 DVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRCCC 475
>gi|226437621 PRAME family member 11 [Homo sapiens]
Length = 436
Score = 606 bits (1562), Expect = e-173
Identities = 312/437 (71%), Positives = 349/437 (79%), Gaps = 4/437 (0%)
Query: 41 VEAFTSRRCEVLKVMVQAWPFPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKL 100
+EAF+ RRCE LK+MVQAWPF LPL L+K P LE V+DG+D LL Q VRPRR KL
Sbjct: 1 MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKL 60
Query: 101 QVLELRDVDENFWTIWSGARPLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFM 160
QVL+L+DV ENFW +WS A C A + V+DCPR E+QPL VF+++ LK + +
Sbjct: 61 QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTL 120
Query: 161 DEDLSFFSGWVQHRRGSVHLCCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCM 220
DE L+ WV+ RR +HLCC K+ M N R+IL+ V D IQ +E+ N W
Sbjct: 121 DEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWILP 179
Query: 221 IV-EFSPYLSQMRNLRKLFIS--DGCRYLLSSDSQEQIAPFTTQFLKLHCLQKLYMNSVS 277
I+ +F+PYL +RNL+KL +S D RY+ +E + FTTQFLKL CLQKLYMNSVS
Sbjct: 180 ILTQFTPYLGHLRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVS 239
Query: 278 FLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLV 337
FLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLV
Sbjct: 240 FLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLV 299
Query: 338 PLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLL 397
PLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPI MATLENLL
Sbjct: 300 PLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLL 359
Query: 398 SHTIILKNLCLELYPAPRESYGADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGTDYCP 457
SHTIILKNLCLELYPAP+ESYGADGTLCWSRF QIRAELMK+VR LRHPKRILF TD CP
Sbjct: 360 SHTIILKNLCLELYPAPQESYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCP 419
Query: 458 DCGNRSFYDLEADQYCC 474
D G+RSFYDLEADQYCC
Sbjct: 420 DHGDRSFYDLEADQYCC 436
>gi|88942379 PREDICTED: PRAME family member [Homo sapiens]
Length = 395
Score = 566 bits (1458), Expect = e-161
Identities = 287/382 (75%), Positives = 316/382 (82%), Gaps = 4/382 (1%)
Query: 96 RRRKLQVLELRDVDENFWTIWSGARPLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCL 155
RR KLQVL+L+DV ENFW +WS A C A ++ V+DCPR +QPL VF+++ L
Sbjct: 15 RRWKLQVLDLQDVCENFWMVWSEAMARGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWL 74
Query: 156 KEKFMDEDLSFFSGWVQHRRGSVHLCCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNM 215
K + +DE L+ WV+ R+ +HLCC K+ M N R+IL+ V D IQ +E+ N
Sbjct: 75 KNRTLDEHLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NC 133
Query: 216 CWPCMIV-EFSPYLSQMRNLRKLFIS--DGCRYLLSSDSQEQIAPFTTQFLKLHCLQKLY 272
W I+ +F+PYL MRNL+KL +S D RY+ +E + FTTQFLKLHCLQKLY
Sbjct: 134 KWVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLHCLQKLY 193
Query: 273 MNSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLT 332
MNSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLT
Sbjct: 194 MNSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLT 253
Query: 333 NYSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMAT 392
NYSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMAT
Sbjct: 254 NYSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMAT 313
Query: 393 LENLLSHTIILKNLCLELYPAPRESYGADGTLCWSRFTQIRAELMKRVRDLRHPKRILFG 452
LENLLSHTIILKNLCLELYPAPRESYGADGTLCWSRFTQIRAELMKRVRDLRHPKRILFG
Sbjct: 314 LENLLSHTIILKNLCLELYPAPRESYGADGTLCWSRFTQIRAELMKRVRDLRHPKRILFG 373
Query: 453 TDYCPDCGNRSFYDLEADQYCC 474
TDYCPDCGNRSFYDLEADQYCC
Sbjct: 374 TDYCPDCGNRSFYDLEADQYCC 395
>gi|124249372 PRAME family member 12 [Homo sapiens]
Length = 483
Score = 550 bits (1418), Expect = e-157
Identities = 289/473 (61%), Positives = 352/473 (74%), Gaps = 10/473 (2%)
Query: 1 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 60
MSLQAP RLLELA QSLL D+ALAI L+ELPRELFPPLF+EAFT R CE L MVQAWP
Sbjct: 1 MSLQAPPRLLELAEQSLLRDRALAIPTLEELPRELFPPLFMEAFTRRCCETLTTMVQAWP 60
Query: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 120
F CLPLGSLMK+ +LEI V++G+D LLAQKVRPRR KLQVL+LR+VDENFW IWSGA
Sbjct: 61 FTCLPLGSLMKSCNLEIFRAVLEGLDALLAQKVRPRRWKLQVLDLRNVDENFWGIWSGAS 120
Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 180
LS PEA+SKR+T +CPR G +QPL V +D+C K +DE L+ F W + R+G +H+
Sbjct: 121 ALS--PEALSKRRTAGNCPRPGGQQPLMVILDLCFKNGMLDECLTHFLEWGKQRKGLLHV 178
Query: 181 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWP---CMIVEFSPYLSQMRNLRKL 237
CC ++ + ++I +L TV D IQ +E+ C P +++ F+PYL QMRNLRKL
Sbjct: 179 CCKELQIFGIAIHRIIEVLNTVELDCIQEVEV---CCPWELSILIRFAPYLGQMRNLRKL 235
Query: 238 FISD-GCRYLLSSDSQEQ-IAPFTTQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLKTSLK 295
+ + + D +EQ + FT+QFLKL QKLYM+SVSFLEGHLDQLL CL+ L+
Sbjct: 236 VLFNIHVSACIPLDRKEQFVIQFTSQFLKLDYFQKLYMHSVSFLEGHLDQLLRCLQAPLE 295
Query: 296 VLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDL 355
+ +T C+L ESDLKHLS CPSI QLK LDL GI LT++S PL +LLE+ ATL+ LDL
Sbjct: 296 TVVMTECLLSESDLKHLSWCPSIRQLKELDLRGITLTHFSPEPLSVLLEQAEATLQTLDL 355
Query: 356 DDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCLELYPAPR 415
+DCGI+DSQ++AILPALSRC +L+TFSFCGN ISMA LENLL HT+ L L LELYPAP
Sbjct: 356 EDCGIVDSQLSAILPALSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPL 415
Query: 416 ESYGADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGTDYCPDCGNRSFYDLE 468
ESY A G LCW RF+Q+ AELMK +RDLR PK I+F T CP CG R+ YDLE
Sbjct: 416 ESYDAQGALCWGRFSQLGAELMKTLRDLRQPKIIVFSTVPCPRCGIRASYDLE 468
>gi|239741053 PREDICTED: similar to Putative PRAME family member 24
[Homo sapiens]
Length = 474
Score = 523 bits (1347), Expect = e-148
Identities = 278/479 (58%), Positives = 350/479 (73%), Gaps = 10/479 (2%)
Query: 1 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 60
MS++AP RLLELA Q LL DQALAIS ++ELPRELFP LF+EAF+ RRCE LK MVQAWP
Sbjct: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
Query: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 120
F LPLGSLMK+P LE L V++G+D LL Q+VRPR+ KLQVL+LR+VDENF I+SGA
Sbjct: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 180
+ PEA+S++QT ++CP TG +QP VF+D+CLK + +DE L+ W + R+G +H+
Sbjct: 121 --ASFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
Query: 181 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWP---CMIVEFSPYLSQMRNLRKL 237
CC ++ + M I + +L V D IQ +E+ C P +V+F+PYL QMRNLRKL
Sbjct: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEV---CCPWELSTLVKFAPYLGQMRNLRKL 235
Query: 238 FISD-GCRYLLSSDSQEQ-IAPFTTQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLKTSLK 295
+ + + D++ Q IA FT+QFLKL Q L M+SVSFLEGHLDQLL CL+ SL+
Sbjct: 236 VLFNIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLE 295
Query: 296 VLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDL 355
++ +T+C+L ESDLKHLS CPSI QLK LDL G+ LT++S PL LLE+V ATL+ LDL
Sbjct: 296 MVVMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDL 355
Query: 356 DDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCLELYPAPR 415
+DCGI+DSQ++AILP LSRC +L+TFSFCGN ISMA LENLL HT+ L L LELYPAP
Sbjct: 356 EDCGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPL 415
Query: 416 ESYGADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGTDYCPDCGNRSFYDLEADQYCC 474
ESY G LCW RF ++ AELMK +RDLR PK I+F T CP CG R+ YDLE C
Sbjct: 416 ESYDTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCLC 474
>gi|59676587 PRAME family member 8 [Homo sapiens]
Length = 474
Score = 523 bits (1347), Expect = e-148
Identities = 278/479 (58%), Positives = 350/479 (73%), Gaps = 10/479 (2%)
Query: 1 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 60
MS++AP RLLELA Q LL DQALAIS ++ELPRELFP LF+EAF+ RRCE LK MVQAWP
Sbjct: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
Query: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 120
F LPLGSLMK+P LE L V++G+D LL Q+VRPR+ KLQVL+LR+VDENF I+SGA
Sbjct: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 180
+ PEA+S++QT ++CP TG +QP VF+D+CLK + +DE L+ W + R+G +H+
Sbjct: 121 --ASFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
Query: 181 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWP---CMIVEFSPYLSQMRNLRKL 237
CC ++ + M I + +L V D IQ +E+ C P +V+F+PYL QMRNLRKL
Sbjct: 179 CCQELQVFGMPIHSIIEVLNMVELDCIQEVEV---CCPWELSTLVKFAPYLGQMRNLRKL 235
Query: 238 FISD-GCRYLLSSDSQEQ-IAPFTTQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLKTSLK 295
+ + + D++ Q IA FT+QFLKL Q L M+SVSFLEGHLDQLL CL+ SL+
Sbjct: 236 VLFNIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLE 295
Query: 296 VLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDL 355
++ +T+C+L ESDLKHLS CPSI QLK LDL G+ LT++S PL LLE+V ATL+ LDL
Sbjct: 296 MVVMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDL 355
Query: 356 DDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCLELYPAPR 415
+DCGI+DSQ++AILP LSRC +L+TFSFCGN ISMA LENLL HT+ L L LELYPAP
Sbjct: 356 EDCGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPL 415
Query: 416 ESYGADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGTDYCPDCGNRSFYDLEADQYCC 474
ESY G LCW RF ++ AELMK +RDLR PK I+F T CP CG R+ YDLE C
Sbjct: 416 ESYDTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCLC 474
>gi|59676593 PRAME family member 7 [Homo sapiens]
Length = 474
Score = 522 bits (1344), Expect = e-148
Identities = 278/479 (58%), Positives = 349/479 (72%), Gaps = 10/479 (2%)
Query: 1 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 60
MS++AP RLLELA Q LL DQALAIS ++ELPRELFP LF+EAF+ RRCE LK MVQAWP
Sbjct: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
Query: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 120
F LPLGSLMK+P LE L V++G+D LL Q+VRPR+ KLQVL+LR+VDENF I+SGA
Sbjct: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 180
+ PEA+S++QT ++CP TG +QP VF+D+CLK + +DE L+ W + R+G +H+
Sbjct: 121 --ASFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
Query: 181 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWP---CMIVEFSPYLSQMRNLRKL 237
CC ++ + M I + +L V D IQ +E+ C P +V+F+PYL QMRNLRKL
Sbjct: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEV---CCPWELSTLVKFAPYLGQMRNLRKL 235
Query: 238 FISD-GCRYLLSSDSQEQ-IAPFTTQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLKTSLK 295
+ + + D++ Q IA FT+QFLKL Q L M+SVSFLEGHLDQLL CL+ SL+
Sbjct: 236 VLFNIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLE 295
Query: 296 VLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDL 355
++ +T+C+L ESDLKHLS CPSI QLK LDL G+ LT++S PL LLE+V ATL+ LDL
Sbjct: 296 MVVMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDL 355
Query: 356 DDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCLELYPAPR 415
+DCGI+DSQ++AILP LSRC +L+TFSFCGN ISMA LENLL HT+ L L LELYPAP
Sbjct: 356 EDCGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPL 415
Query: 416 ESYGADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGTDYCPDCGNRSFYDLEADQYCC 474
ESY G LCW RF ++ AELMK RDLR PK I+F T CP CG R+ YDLE C
Sbjct: 416 ESYDTQGALCWGRFAELGAELMKTPRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCLC 474
>gi|194018546 PRAME family member 10 [Homo sapiens]
Length = 474
Score = 504 bits (1299), Expect = e-143
Identities = 272/462 (58%), Positives = 327/462 (70%), Gaps = 1/462 (0%)
Query: 1 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 60
MSLQAP RLLELAGQSLL +Q L I LDELPRE+FP +F+EAF+ RR E LK+MVQAWP
Sbjct: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
Query: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 120
F LPLGSLMKT LE L V+ G+D L+AQKVRPRR KLQVL+LRDVDENFWTIWSGAR
Sbjct: 61 FLSLPLGSLMKTLHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 180
LSCSPEAMSKRQTVEDCPR GE QPLKVF+D+CLKE +DE LS+ GW+ +RRG VHL
Sbjct: 121 VLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
Query: 181 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSPYLSQMRNLRKLFIS 240
CC+KV NYSM +FRN+LE +YPDSIQ LE+W C +F+PYLSQM NLR+LF++
Sbjct: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLA 240
Query: 241 DGC-RYLLSSDSQEQIAPFTTQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLTI 299
G R L S I + FL L+ Q LY+ +S ++ HL+ LL LK L
Sbjct: 241 FGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIF 300
Query: 300 TNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDCG 359
++ L + D++ LSQ PS+SQLK L L I + L PL +LLEKVAATL+ L L DC
Sbjct: 301 SDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCR 360
Query: 360 IIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCLELYPAPRESYG 419
I D Q+ +LPALS C +L TF+F GN SM L++LL HT L L LELYPAP ES
Sbjct: 361 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTGGLSKLGLELYPAPLESLD 420
Query: 420 ADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGTDYCPDCGN 461
G + W T IRAELM+ +R++R PKRI FG CP+CG+
Sbjct: 421 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPNCGS 462
>gi|157426839 PRAME family member 17 [Homo sapiens]
Length = 474
Score = 493 bits (1268), Expect = e-139
Identities = 270/462 (58%), Positives = 318/462 (68%), Gaps = 1/462 (0%)
Query: 1 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 60
MSLQ+P RLLELAGQSLL +Q L I ILDELPRE+FP +F+EA + R E LK+MVQAWP
Sbjct: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
Query: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 120
F LPLGSLMKTP LE L V+ G+D LLAQK+RPRR KLQVL+LRDVD NFWTIWSGAR
Sbjct: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 180
LSCSPEAMSKRQTVED PRTGE QPLKVF+D+C KE +DE LS+ W+ +RRG VHL
Sbjct: 121 ALSCSPEAMSKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
Query: 181 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSPYLSQMRNLRKLFIS 240
CC KV NYSM +FRN+L+ VYPDSIQ LEI C +F+PYLSQM NLRKLF++
Sbjct: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
Query: 241 DGCRYLLSSDSQEQIAP-FTTQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLTI 299
G L Q+Q P FL L+ Q LY+ +S ++ HL+ LL CLK L
Sbjct: 241 FGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTFIF 300
Query: 300 TNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDCG 359
+ L + D++ LSQ PS+SQLK L L I + +L PL LLEKVAATLE L L DC
Sbjct: 301 CHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKDCQ 360
Query: 360 IIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCLELYPAPRESYG 419
I DSQ+ +LPALSRC +L TF F GN S L++LL HT L L LELYPAP E
Sbjct: 361 IQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLECLD 420
Query: 420 ADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGTDYCPDCGN 461
G + W IRAELM +R++R PKRI FG CP CG+
Sbjct: 421 NRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGS 462
>gi|113865933 PRAME family member 16 [Homo sapiens]
Length = 474
Score = 491 bits (1263), Expect = e-139
Identities = 269/462 (58%), Positives = 317/462 (68%), Gaps = 1/462 (0%)
Query: 1 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 60
MSLQ+P RLLELAGQSLL +Q L I ILDELPRE+FP +F+EA + R E LK+MVQAWP
Sbjct: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
Query: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 120
F LPLGSLMKTP LE L V+ G+D LLAQK+RPRR KLQVL+LRDVD NFWTIWSGAR
Sbjct: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 180
LSCSPEAM KRQTVED PRTGE QPLKVF+D+C KE +DE LS+ W+ +RRG VHL
Sbjct: 121 ALSCSPEAMRKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
Query: 181 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSPYLSQMRNLRKLFIS 240
CC KV NYSM +FRN+L+ VYPDSIQ LEI C +F+PYLSQM NLRKLF++
Sbjct: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
Query: 241 DGCRYLLSSDSQEQIAP-FTTQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLTI 299
G L Q+Q P FL L+ Q LY+ +S ++ HL+ LL CLK L
Sbjct: 241 FGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTFIF 300
Query: 300 TNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDCG 359
+ L + D++ LSQ PS+SQLK L L I + +L PL LLEKVAATLE L L DC
Sbjct: 301 CHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKDCQ 360
Query: 360 IIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCLELYPAPRESYG 419
I DSQ+ +LPALSRC +L TF F GN S L++LL HT L L LELYPAP E
Sbjct: 361 IQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLECLD 420
Query: 420 ADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGTDYCPDCGN 461
G + W IRAELM +R++R PKRI FG CP CG+
Sbjct: 421 NRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGS 462
>gi|239741051 PREDICTED: similar to PRAME family member 10 [Homo
sapiens]
Length = 426
Score = 471 bits (1213), Expect = e-133
Identities = 259/461 (56%), Positives = 306/461 (66%), Gaps = 47/461 (10%)
Query: 1 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 60
MSLQAP RLLELAGQSLL +Q L I LDELPRE+FP +F+EAF+ RR E LK+MVQAWP
Sbjct: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
Query: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 120
F LPLGSLMKTP LE L V+ G+D L+AQKVRPRR KLQVL+LRDVDENFWTIWSGAR
Sbjct: 61 FLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 180
LSCSPEAMSKRQTVEDCPR GE+QPLKVF+D+CLKE +DE LS+ GW+ +RRG VHL
Sbjct: 121 VLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
Query: 181 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSPYLSQMRNLRKLFIS 240
CC+KV NYSM +FRN+LE +YPDSIQ LE+W C +F+PYLSQM NLR+LF
Sbjct: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFFP 240
Query: 241 DGCRYLLSSDSQEQIAPFTTQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLTIT 300
RY LK L +
Sbjct: 241 ---RY--------------------------------------------LKNPLGAFIFS 253
Query: 301 NCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDCGI 360
+ L + D++ LSQ PS+SQLK L L I + +L PL +LLEKVAATL+ L L DC I
Sbjct: 254 DAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTNLEPLGVLLEKVAATLKTLVLKDCRI 313
Query: 361 IDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCLELYPAPRESYGA 420
D Q+ +LPALS C +L TF+F GN SM L++LL HT L L LELYPAP ES
Sbjct: 314 QDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLDY 373
Query: 421 DGTLCWSRFTQIRAELMKRVRDLRHPKRILFGTDYCPDCGN 461
G + W T IRAELM+ +R++R PKRI FG CP CG+
Sbjct: 374 KGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGS 414
>gi|239741055 PREDICTED: similar to PRAME family member 10 [Homo
sapiens]
Length = 426
Score = 471 bits (1211), Expect = e-133
Identities = 259/461 (56%), Positives = 305/461 (66%), Gaps = 47/461 (10%)
Query: 1 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 60
MSLQAP RLLELAGQSLL +Q L I LDELPRE+FP +F+EAF+ RR E LK+MVQAWP
Sbjct: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
Query: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 120
F LPLGSLMKTP LE L V+ G+D L+AQKVRPRR KLQVL+LRDVDENFWTIWSGAR
Sbjct: 61 FLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 180
LSCSPEAMSKRQTVEDCPR GE+QPLKVF+D+CLKE +DE LS+ GW+ +RRG VHL
Sbjct: 121 VLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
Query: 181 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSPYLSQMRNLRKLFIS 240
CC+KV NYSM +FRN+LE +YPDSIQ LE+W C +F+PYLSQM NLR+LF
Sbjct: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFFP 240
Query: 241 DGCRYLLSSDSQEQIAPFTTQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLTIT 300
RY LK L +
Sbjct: 241 ---RY--------------------------------------------LKNPLGAFIFS 253
Query: 301 NCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDCGI 360
+ L + D++ LSQ PS+SQLK L L I + L PL +LLEKVAATL+ L L DC I
Sbjct: 254 DAYLADRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCRI 313
Query: 361 IDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCLELYPAPRESYGA 420
D Q+ +LPALS C +L TF+F GN SM L++LL HT L L LELYPAP ES
Sbjct: 314 QDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLDY 373
Query: 421 DGTLCWSRFTQIRAELMKRVRDLRHPKRILFGTDYCPDCGN 461
G + W T IRAELM+ +R++R PKRI FG CP CG+
Sbjct: 374 KGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGS 414
>gi|12738831 PRAME family member 1 [Homo sapiens]
Length = 474
Score = 469 bits (1208), Expect = e-132
Identities = 258/475 (54%), Positives = 321/475 (67%), Gaps = 2/475 (0%)
Query: 1 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 60
MS+QAP RLLELAGQSLL DQAL+IS ++ELPR L+ PLF+EAF+ R + L VMVQAWP
Sbjct: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFSRRHFQTLTVMVQAWP 60
Query: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 120
F CLPLGSLMKT LE L +++G+ LL QK RPRR KLQVL+LRDVDENFW W GA
Sbjct: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 180
LSC PE SKRQT EDCPR GE QPLKVF+D+CLKE DE L + WV RRG VHL
Sbjct: 121 ALSCFPETTSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
Query: 181 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSPYLSQMRNLRKLFIS 240
CC+K+VNY I R L+ +Y +SIQ LEI NM WP +I + YL +M+NLRKL S
Sbjct: 181 CCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
Query: 241 DGCRYLLSSDSQEQ-IAPFTTQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLTI 299
Y ++ Q + +A F++ FL+L LQ L + ++F GHL+QL+ CL+ L+ L +
Sbjct: 241 RCHHYTSDNELQGRLVAKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
Query: 300 TNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDCG 359
T LLE D+K LSQ PS+ LK L+LS + L SL PL LLEK+AA+L+ L L+ C
Sbjct: 301 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLKTLILEGCQ 360
Query: 360 IIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCLELYPAPRESYG 419
I SQ++AILPALSRC +L TF F N +S+ L++LL HT L L LE YPAP ES
Sbjct: 361 IHYSQLSAILPALSRCSQLTTFYFGRNCMSIDALKDLLRHTSGLSKLSLETYPAPEESLN 420
Query: 420 ADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGTDYCPDCGNRSFYDLEADQYCC 474
+ + W FT +RAELM +R++R PKRI G CP CG+ +LE CC
Sbjct: 421 SLVRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELEL-HLCC 474
>gi|66954681 PRAME family member 13 [Homo sapiens]
Length = 474
Score = 469 bits (1207), Expect = e-132
Identities = 258/476 (54%), Positives = 319/476 (67%), Gaps = 4/476 (0%)
Query: 1 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 60
MS+QAP RLLELAGQSLL DQAL+IS ++ELPR L+ PLF+EAF R + L VMVQAWP
Sbjct: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
Query: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 120
F CLPLGSLMKT LE L +++G+ LL QK RPRR KLQVL+LRDVDENFW W GA
Sbjct: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 180
LSC PE MSKRQT EDCPR GE QPLKVF+D+CLKE DE L + WV RRG VHL
Sbjct: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
Query: 181 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSPYLSQMRNLRKLFIS 240
CC+K+VNY I + R L+ +Y +SIQ LEI NM WP +I + YL +M+NLRKL S
Sbjct: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
Query: 241 DGCRYLLSSDSQE--QIAPFTTQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLT 298
C + +S + E + F++ FL+L LQ L + ++F GHL+QL+ CL+ L+ L
Sbjct: 241 -RCHHSMSDNELEGRLVTKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLE 299
Query: 299 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 358
+T LLE D+K LSQ PS+ LK L+LS + L SL PL LLEK+AA+LE L L+ C
Sbjct: 300 LTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGC 359
Query: 359 GIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCLELYPAPRESY 418
I SQ++AILP LS C +L TF F N +SM L++LL HT L L LE YPAP ES
Sbjct: 360 QIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLRHTSGLSKLSLETYPAPEESL 419
Query: 419 GADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGTDYCPDCGNRSFYDLEADQYCC 474
+ + W F +RAELM +R++R PKRI G CP CG+ +LE CC
Sbjct: 420 NSLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELEL-HLCC 474
>gi|12738834 PRAME family member 2 [Homo sapiens]
Length = 474
Score = 459 bits (1182), Expect = e-129
Identities = 258/476 (54%), Positives = 315/476 (66%), Gaps = 4/476 (0%)
Query: 1 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 60
MS+QAP RLLELAGQSLL DQAL+IS ++ELPR L+ PLF EAF+ R + L VMVQAWP
Sbjct: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFREAFSRRHFQTLTVMVQAWP 60
Query: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 120
F CLPL SLMKT LE L +++G+ LL QK RPRR KLQVL+LRDVDENFW W GA
Sbjct: 61 FTCLPLVSLMKTLHLEPLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 180
LSC PEAMSKRQT EDCPRTGE QPLKVF+D+CLKE DE L + WV RRG VHL
Sbjct: 121 ALSCFPEAMSKRQTAEDCPRTGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
Query: 181 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSPYLSQMRNLRKLFIS 240
CC+K+VNY I R L+ +Y +SI LEI N CWP +I + YL +M+ L KL S
Sbjct: 181 CCSKLVNYLTPIKYLRKSLKIIYINSIGELEIHNTCWPHLIRKLYCYLKEMKTLCKLVFS 240
Query: 241 DGCRYLLSSDSQE--QIAPFTTQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLT 298
C + S + E + FT+ FL+L LQ L + ++F GHL+QL+ CL+ L+ L
Sbjct: 241 -RCHHYTSDNELEGWLVTRFTSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLE 299
Query: 299 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 358
+T LLE DLK LSQ PS+ LK L+LS + L SL PL LLEK+AA+LE L L+ C
Sbjct: 300 LTCGNLLEEDLKCLSQFPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLVLEGC 359
Query: 359 GIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCLELYPAPRESY 418
I SQ++AILP LS C +L TF F N +S+ L++LL HT L L LE YPAP ES
Sbjct: 360 QIHYSQLSAILPGLSCCSQLTTFYFGSNCMSIDALKDLLRHTSGLSKLSLETYPAPEESL 419
Query: 419 GADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGTDYCPDCGNRSFYDLEADQYCC 474
+ + W FT +RAELM +R+ R PKRI G CP CG+ +LE CC
Sbjct: 420 NSLVRVNWEIFTPLRAELMCTLREFRQPKRIFIGPTPCPSCGSSPSEELEL-HLCC 474
>gi|153792140 PRAME family member 14 [Homo sapiens]
Length = 426
Score = 424 bits (1089), Expect = e-118
Identities = 242/474 (51%), Positives = 291/474 (61%), Gaps = 48/474 (10%)
Query: 1 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 60
MS+QAP RLLELAGQSLL DQAL+IS ++ELPR L+ PLF+EAF R + L VMVQAWP
Sbjct: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
Query: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 120
F CLPLGSLMKT LE L +++G+ LL QK RPRR KLQVL+LRDVDENFW W GA
Sbjct: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 180
LSC PE MSKRQT EDCPR GE QPLKVF+D+CLKE DE L + WV RRG VHL
Sbjct: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
Query: 181 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSPYLSQMRNLRKLFIS 240
CC+K+VNY I + R L+ +Y +SIQ LEI NM WP +I + YL +M+NLRKL S
Sbjct: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
Query: 241 DGCRYLLSSDSQEQIAPFTTQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLTIT 300
CL+ L+ L +T
Sbjct: 241 -----------------------------------------------RCLQNPLENLELT 253
Query: 301 NCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDCGI 360
LLE D+K LSQ PS+ LK L+LS + L SL PL LLEK+AA+LE L L+ C I
Sbjct: 254 YGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGCQI 313
Query: 361 IDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCLELYPAPRESYGA 420
SQ++AILP LS C +L TF F N +SM L++LL HT L L LE YPAP ES +
Sbjct: 314 HYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLCHTSGLSKLSLETYPAPEESLNS 373
Query: 421 DGTLCWSRFTQIRAELMKRVRDLRHPKRILFGTDYCPDCGNRSFYDLEADQYCC 474
+ W F +RAELM +R++R PKRI G CP CG+ +LE CC
Sbjct: 374 LVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELEL-HLCC 426
>gi|46249373 preferentially expressed antigen in melanoma [Homo
sapiens]
Length = 509
Score = 398 bits (1023), Expect = e-111
Identities = 230/478 (48%), Positives = 306/478 (64%), Gaps = 14/478 (2%)
Query: 5 APRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWPFPCL 64
+PRRL+ELAGQSLL D+ALAI+ L+ LPRELFPPLF+ AF R + LK MVQAWPF CL
Sbjct: 22 SPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCL 81
Query: 65 PLGSLMKTPDL--EILHYVVDGIDCLLAQKVRPRRRKLQVLELR-DVDENFWTIWSGARP 121
PLG LMK L E V+DG+D LLAQ+VRPRR KLQVL+LR + ++FWT+WSG R
Sbjct: 82 PLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRA 141
Query: 122 LSCS---PEA---MSKRQTVEDCPRTGEKQ--PLKVFMDVCLKEKFMDEDLSFFSGWVQH 173
S PEA M+K++ V+ E+ P++V +D+ LKE DE S+ V+
Sbjct: 142 SLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVKR 201
Query: 174 RRGSVHLCCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSPYLSQMRN 233
++ + LCC K+ ++M + + + IL+ V DSI+ LE+ + +FSPYL QM N
Sbjct: 202 KKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMIN 261
Query: 234 LRKLFISD--GCRYLLSSDSQEQIAPFTTQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLK 291
LR+L +S Y+ ++ IA FT+QFL L CLQ LY++S+ FL G LDQLL +
Sbjct: 262 LRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHVM 321
Query: 292 TSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLE 351
L+ L+ITNC L E D+ HLSQ PS+SQL L LSG+ LT+ S PLQ LLE+ +ATL+
Sbjct: 322 NPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATLQ 381
Query: 352 YLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCLELY 411
L D+CGI D Q+ A+LP+LS C +L T SF GN IS++ L++LL H I L NL LY
Sbjct: 382 DLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVLY 441
Query: 412 PAPRESY-GADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGTDYCPDCGNRSFYDLE 468
P P ESY GTL R + A L + + +L P + + CP CG+R+FYD E
Sbjct: 442 PVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRTFYDPE 499
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.139 0.436
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,909,803
Number of Sequences: 37866
Number of extensions: 778796
Number of successful extensions: 2268
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 45
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 2119
Number of HSP's gapped (non-prelim): 87
length of query: 474
length of database: 18,247,518
effective HSP length: 106
effective length of query: 368
effective length of database: 14,233,722
effective search space: 5238009696
effective search space used: 5238009696
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.