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Search of human proteins with 239741043
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239741043 PREDICTED: PRAME family member 11 [Homo sapiens]
(513 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239741043 PREDICTED: PRAME family member 11 [Homo sapiens] 1051 0.0
gi|148356236 PRAME family member 15 [Homo sapiens] 941 0.0
gi|61102721 PRAME family member 9 [Homo sapiens] 941 0.0
gi|59958373 PRAME family member 4 [Homo sapiens] 933 0.0
gi|61696142 PRAME family member 5 [Homo sapiens] 923 0.0
gi|58219004 PRAME family member 6 [Homo sapiens] 922 0.0
gi|239741045 PREDICTED: PRAME family member 23 [Homo sapiens] 918 0.0
gi|226437621 PRAME family member 11 [Homo sapiens] 897 0.0
gi|153792112 PRAME family member 20 [Homo sapiens] 769 0.0
gi|153945800 PRAME family member 21 [Homo sapiens] 769 0.0
gi|88942379 PREDICTED: PRAME family member [Homo sapiens] 748 0.0
gi|239741047 PREDICTED: PRAME family member 25-like [Homo sapiens] 661 0.0
gi|239741053 PREDICTED: similar to Putative PRAME family member ... 565 e-161
gi|59676593 PRAME family member 7 [Homo sapiens] 564 e-161
gi|59676587 PRAME family member 8 [Homo sapiens] 563 e-160
gi|124249372 PRAME family member 12 [Homo sapiens] 556 e-158
gi|46249373 preferentially expressed antigen in melanoma [Homo s... 436 e-122
gi|46249371 preferentially expressed antigen in melanoma [Homo s... 436 e-122
gi|46249369 preferentially expressed antigen in melanoma [Homo s... 436 e-122
gi|46249367 preferentially expressed antigen in melanoma [Homo s... 436 e-122
gi|5174641 preferentially expressed antigen in melanoma [Homo sa... 436 e-122
gi|154800493 PRAME family member 22 [Homo sapiens] 420 e-117
gi|194306638 PRAME family member 3 [Homo sapiens] 414 e-115
gi|153791443 PRAME family member 18 [Homo sapiens] 412 e-115
gi|194306635 PRAME family member 19 [Homo sapiens] 408 e-114
gi|113865933 PRAME family member 16 [Homo sapiens] 407 e-113
gi|157426839 PRAME family member 17 [Homo sapiens] 404 e-113
gi|66954681 PRAME family member 13 [Homo sapiens] 404 e-112
gi|12738831 PRAME family member 1 [Homo sapiens] 402 e-112
gi|194018546 PRAME family member 10 [Homo sapiens] 402 e-112
>gi|239741043 PREDICTED: PRAME family member 11 [Homo sapiens]
Length = 513
Score = 1051 bits (2719), Expect = 0.0
Identities = 513/513 (100%), Positives = 513/513 (100%)
Query: 1 MQERPKVFKPGVPAWFFLRSEHLLDYIQICFPCRFMKMSIRIPPRLLELXGRSLLRDQAL 60
MQERPKVFKPGVPAWFFLRSEHLLDYIQICFPCRFMKMSIRIPPRLLEL GRSLLRDQAL
Sbjct: 1 MQERPKVFKPGVPAWFFLRSEHLLDYIQICFPCRFMKMSIRIPPRLLELXGRSLLRDQAL 60
Query: 61 AVSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLD 120
AVSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLD
Sbjct: 61 AVSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLD 120
Query: 121 GLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKTPVQDCPRMRE 180
GLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKTPVQDCPRMRE
Sbjct: 121 GLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKTPVQDCPRMRE 180
Query: 181 RQPLTVFVELWLKNRTLDEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVN 240
RQPLTVFVELWLKNRTLDEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVN
Sbjct: 181 RQPLTVFVELWLKNRTLDEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVN 240
Query: 241 LDCIQEVEVNCKWILPILTQFTPYLGHLRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQ 300
LDCIQEVEVNCKWILPILTQFTPYLGHLRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQ
Sbjct: 241 LDCIQEVEVNCKWILPILTQFTPYLGHLRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQ 300
Query: 301 FLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQL 360
FLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQL
Sbjct: 301 FLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQL 360
Query: 361 KTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTF 420
KTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTF
Sbjct: 361 KTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTF 420
Query: 421 SFCGNPICMATLENLLSHTIILKNLCLELYPAPQESYGADGTLCWSRFAQIRAELMKKVR 480
SFCGNPICMATLENLLSHTIILKNLCLELYPAPQESYGADGTLCWSRFAQIRAELMKKVR
Sbjct: 421 SFCGNPICMATLENLLSHTIILKNLCLELYPAPQESYGADGTLCWSRFAQIRAELMKKVR 480
Query: 481 HLRHPKRILFCTDNCPDHGDRSFYDLEADQYCC 513
HLRHPKRILFCTDNCPDHGDRSFYDLEADQYCC
Sbjct: 481 HLRHPKRILFCTDNCPDHGDRSFYDLEADQYCC 513
>gi|148356236 PRAME family member 15 [Homo sapiens]
Length = 478
Score = 941 bits (2433), Expect = 0.0
Identities = 461/478 (96%), Positives = 469/478 (98%)
Query: 36 MKMSIRIPPRLLELXGRSLLRDQALAVSTLEELPTELFPPLFMEAFSRRRCEALKLMVQA 95
MKMSIR PPRLLEL GRSLLRDQALA+STLEELPTELFPPLFMEAFSRRRCEALKLMVQA
Sbjct: 1 MKMSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQA 60
Query: 96 WPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSE 155
WPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSE
Sbjct: 61 WPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSE 120
Query: 156 AMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTLDEYLTCLLLWVKQRRDLL 215
AMAHGCFLNAKRNK PVQDCPRMR RQPLTVFVELWLKNRTLDEYLT LLLWVKQR+DLL
Sbjct: 121 AMAHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLL 180
Query: 216 HLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPILTQFTPYLGHLRNLQKLV 275
HLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKW+LPILTQFTPYLGH+RNLQKLV
Sbjct: 181 HLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLV 240
Query: 276 LSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKV 335
LSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKV
Sbjct: 241 LSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKV 300
Query: 336 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 395
LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD
Sbjct: 301 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 360
Query: 396 DCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCLELYPAPQE 455
DCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLC+ELYPAP+E
Sbjct: 361 DCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRE 420
Query: 456 SYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPDHGDRSFYDLEADQYCC 513
SYGADGTLCWSRFAQIRAELM +VR LRHPKRILFCTD CPD G+RSFYDLEADQYCC
Sbjct: 421 SYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
>gi|61102721 PRAME family member 9 [Homo sapiens]
Length = 478
Score = 941 bits (2433), Expect = 0.0
Identities = 461/478 (96%), Positives = 469/478 (98%)
Query: 36 MKMSIRIPPRLLELXGRSLLRDQALAVSTLEELPTELFPPLFMEAFSRRRCEALKLMVQA 95
MKMSIR PPRLLEL GRSLLRDQALA+STLEELPTELFPPLFMEAFSRRRCEALKLMVQA
Sbjct: 1 MKMSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQA 60
Query: 96 WPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSE 155
WPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSE
Sbjct: 61 WPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSE 120
Query: 156 AMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTLDEYLTCLLLWVKQRRDLL 215
AMAHGCFLNAKRNK PVQDCPRMR RQPLTVFVELWLKNRTLDEYLT LLLWVKQR+DLL
Sbjct: 121 AMAHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLL 180
Query: 216 HLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPILTQFTPYLGHLRNLQKLV 275
HLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKW+LPILTQFTPYLGH+RNLQKLV
Sbjct: 181 HLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLV 240
Query: 276 LSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKV 335
LSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKV
Sbjct: 241 LSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKV 300
Query: 336 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 395
LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD
Sbjct: 301 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 360
Query: 396 DCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCLELYPAPQE 455
DCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLC+ELYPAP+E
Sbjct: 361 DCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRE 420
Query: 456 SYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPDHGDRSFYDLEADQYCC 513
SYGADGTLCWSRFAQIRAELM +VR LRHPKRILFCTD CPD G+RSFYDLEADQYCC
Sbjct: 421 SYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
>gi|59958373 PRAME family member 4 [Homo sapiens]
Length = 478
Score = 933 bits (2412), Expect = 0.0
Identities = 455/478 (95%), Positives = 466/478 (97%)
Query: 36 MKMSIRIPPRLLELXGRSLLRDQALAVSTLEELPTELFPPLFMEAFSRRRCEALKLMVQA 95
MKMSI PPRLLEL GRSLLRDQALA+STLEELPTELFPPLFMEAFSRRRCEALKLMVQ+
Sbjct: 1 MKMSIWTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQS 60
Query: 96 WPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSE 155
WPFRRLPLRPLIKMPCLEAFQAVLDGLDALL GVRPRRWKLQVLDLQDVCENFWMVWSE
Sbjct: 61 WPFRRLPLRPLIKMPCLEAFQAVLDGLDALLNLGVRPRRWKLQVLDLQDVCENFWMVWSE 120
Query: 156 AMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTLDEYLTCLLLWVKQRRDLL 215
AMAHGCFLNAKRNK PV+DCPRMR RQPLTVFVELWLKNRTLDEYLTCLLLWVKQR+DLL
Sbjct: 121 AMAHGCFLNAKRNKKPVEDCPRMRGRQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLL 180
Query: 216 HLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPILTQFTPYLGHLRNLQKLV 275
HLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKW+LPILTQFTPYLGH+RNLQKL+
Sbjct: 181 HLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLI 240
Query: 276 LSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKV 335
LSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLK
Sbjct: 241 LSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKF 300
Query: 336 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 395
LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD
Sbjct: 301 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 360
Query: 396 DCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCLELYPAPQE 455
DCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLC+ELYPAP+E
Sbjct: 361 DCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRE 420
Query: 456 SYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPDHGDRSFYDLEADQYCC 513
SYGADGTLCWSRFAQIRAELM +VR LRHPKRILFCTD CPD G+RSFYDLEADQYCC
Sbjct: 421 SYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
>gi|61696142 PRAME family member 5 [Homo sapiens]
Length = 476
Score = 923 bits (2386), Expect = 0.0
Identities = 454/476 (95%), Positives = 463/476 (97%)
Query: 38 MSIRIPPRLLELXGRSLLRDQALAVSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 97
MSIR PPRLLEL GRSLLRDQALA+STLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
Query: 98 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 157
FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGV PRRWKLQVLDLQDVCENFWMVWSEAM
Sbjct: 61 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
Query: 158 AHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTLDEYLTCLLLWVKQRRDLLHL 217
AHGCFLNAKRNK PVQDCPRMR +QPLTVFVELWLKNRTLDEYLTCLLLWVKQR+DLLHL
Sbjct: 121 AHGCFLNAKRNKKPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
Query: 218 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPILTQFTPYLGHLRNLQKLVLS 277
CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKW+LPILTQFTPYLGH+RNLQKLVLS
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 240
Query: 278 HMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLT 337
HMDVSRYVSPEQKKEIVTQFTTQFLKL CLQKL MNSVSFLEGHLDQLLSCLKTSLKVLT
Sbjct: 241 HMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVLT 300
Query: 338 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 397
ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC
Sbjct: 301 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 360
Query: 398 GIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCLELYPAPQESY 457
GIIDSQVNAILPALSRCFELNTFSFCGNPI MATLENLLSHTIILKNLC+ELYPAP+ESY
Sbjct: 361 GIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRESY 420
Query: 458 GADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPDHGDRSFYDLEADQYCC 513
ADGTLCWSRFAQIRAELMK+VR LRHPKRILFCTD CPD G+RSFYDLEADQ CC
Sbjct: 421 DADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQCCC 476
>gi|58219004 PRAME family member 6 [Homo sapiens]
Length = 476
Score = 922 bits (2384), Expect = 0.0
Identities = 454/476 (95%), Positives = 463/476 (97%)
Query: 38 MSIRIPPRLLELXGRSLLRDQALAVSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 97
MSIR PPRLLEL GRSLLRDQALA+STLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
Query: 98 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 157
FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGV PRRWKLQVLDLQDVCENFWMVWSEAM
Sbjct: 61 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
Query: 158 AHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTLDEYLTCLLLWVKQRRDLLHL 217
A GCFLNAKRNKTPVQDCPRMR +QPLTVFVELWLKNRTLDEYLTCLLLWVKQR+DLLHL
Sbjct: 121 ARGCFLNAKRNKTPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
Query: 218 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPILTQFTPYLGHLRNLQKLVLS 277
CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKW+LPILTQFTPYLGH+RNLQKLVLS
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 240
Query: 278 HMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLT 337
HMDVSRYVSPEQKKEIVTQFTTQFLKL CLQKL MNSVSFLEGHLDQLLSCLKTSLKVLT
Sbjct: 241 HMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVLT 300
Query: 338 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 397
ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC
Sbjct: 301 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 360
Query: 398 GIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCLELYPAPQESY 457
GIIDSQVNAILPALSRCFELNTFSFCGNPI MATLENLLSHTIILKNLC+ELYPAP+ESY
Sbjct: 361 GIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRESY 420
Query: 458 GADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPDHGDRSFYDLEADQYCC 513
ADGTLCWSRFAQIRAELMK+VR LRHPKRILFCTD CPD G+RSFYDLEADQ CC
Sbjct: 421 DADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQCCC 476
>gi|239741045 PREDICTED: PRAME family member 23 [Homo sapiens]
Length = 476
Score = 918 bits (2373), Expect = 0.0
Identities = 452/476 (94%), Positives = 461/476 (96%)
Query: 38 MSIRIPPRLLELXGRSLLRDQALAVSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 97
MSIR PPRLLEL GRSLLRDQALA+STLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
Query: 98 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 157
FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGV PRRWKLQVLDLQDVCENFWMVWSEAM
Sbjct: 61 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
Query: 158 AHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTLDEYLTCLLLWVKQRRDLLHL 217
AHGCFLNAKRNK PVQDCPRMR +QPLTVFVELWLKNRTLDEYLTCLLLWVKQR+DLLHL
Sbjct: 121 AHGCFLNAKRNKKPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
Query: 218 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPILTQFTPYLGHLRNLQKLVLS 277
CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKW+LPILTQFTPYLGH+RNLQKLVLS
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 240
Query: 278 HMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLT 337
HMDVSRYVSPEQKKEIVTQFTTQFLKL CLQKL MNSVSFLEGHLDQLLSCLKTSLKVLT
Sbjct: 241 HMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVLT 300
Query: 338 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 397
ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC
Sbjct: 301 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 360
Query: 398 GIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCLELYPAPQESY 457
GIIDSQVNAILPALS CFELNTFSFCGNPI MATLENLLSHTIILKNLC+ELYPAP+ESY
Sbjct: 361 GIIDSQVNAILPALSCCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRESY 420
Query: 458 GADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPDHGDRSFYDLEADQYCC 513
ADGTLCWSRF QIRAELMK+VR LRHPKRILFCTD CPD G+RSFYDLEADQ CC
Sbjct: 421 DADGTLCWSRFPQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQCCC 476
>gi|226437621 PRAME family member 11 [Homo sapiens]
Length = 436
Score = 897 bits (2319), Expect = 0.0
Identities = 436/436 (100%), Positives = 436/436 (100%)
Query: 78 MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKL 137
MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKL
Sbjct: 1 MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKL 60
Query: 138 QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTL 197
QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTL
Sbjct: 61 QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTL 120
Query: 198 DEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPI 257
DEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPI
Sbjct: 121 DEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPI 180
Query: 258 LTQFTPYLGHLRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSF 317
LTQFTPYLGHLRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSF
Sbjct: 181 LTQFTPYLGHLRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSF 240
Query: 318 LEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVP 377
LEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVP
Sbjct: 241 LEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVP 300
Query: 378 LQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLS 437
LQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLS
Sbjct: 301 LQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLS 360
Query: 438 HTIILKNLCLELYPAPQESYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPD 497
HTIILKNLCLELYPAPQESYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPD
Sbjct: 361 HTIILKNLCLELYPAPQESYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPD 420
Query: 498 HGDRSFYDLEADQYCC 513
HGDRSFYDLEADQYCC
Sbjct: 421 HGDRSFYDLEADQYCC 436
>gi|153792112 PRAME family member 20 [Homo sapiens]
Length = 475
Score = 769 bits (1986), Expect = 0.0
Identities = 383/476 (80%), Positives = 412/476 (86%), Gaps = 1/476 (0%)
Query: 38 MSIRIPPRLLELXGRSLLRDQALAVSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 97
MSIR PPRLLEL GRSLLRD+ALA+STLEELPTELFPPLFMEAFSRR CEALKLMVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60
Query: 98 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 157
F RLPL L+K PC E FQAVLDGLDALLT VR RRWKLQVLDLQDV ENFWMVWSEAM
Sbjct: 61 FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120
Query: 158 AHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTLDEYLTCLLLWVKQRRDLLHL 217
A C NA N+ PVQDCPRMR +QPLTVF++L LKNRTLDEY TCL LWVKQR L+HL
Sbjct: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180
Query: 218 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPILTQFTPYLGHLRNLQKLVLS 277
CCKKLK+LGM F NIR+ILK VNLDCIQEVEVNC W LP+L +FTPYLG +RNL+KLVLS
Sbjct: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTLPVLAEFTPYLGQMRNLRKLVLS 240
Query: 278 HMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLT 337
+D SRY+SPEQKKE VTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQ+LSCLKTSL +L
Sbjct: 241 DID-SRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILA 299
Query: 338 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 397
ITNCVLLESDLKHLS+ PSI QLKTLDLSG RL N+SLVPLQ+LLEKVAATLEYLDLDDC
Sbjct: 300 ITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDC 359
Query: 398 GIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCLELYPAPQESY 457
GI+DSQVNAILPALSRCFEL TFSF GNPI ATLENLL HTI L NLCLELYPAP+ESY
Sbjct: 360 GIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESY 419
Query: 458 GADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPDHGDRSFYDLEADQYCC 513
G +C SRFAQ+ AELM +VR LR P+RILFCTD CP G+RS YDLE D+ CC
Sbjct: 420 DVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRCCC 475
>gi|153945800 PRAME family member 21 [Homo sapiens]
Length = 475
Score = 769 bits (1986), Expect = 0.0
Identities = 383/476 (80%), Positives = 412/476 (86%), Gaps = 1/476 (0%)
Query: 38 MSIRIPPRLLELXGRSLLRDQALAVSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 97
MSIR PPRLLEL GRSLLRD+ALA+STLEELPTELFPPLFMEAFSRR CEALKLMVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60
Query: 98 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 157
F RLPL L+K PC E FQAVLDGLDALLT VR RRWKLQVLDLQDV ENFWMVWSEAM
Sbjct: 61 FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120
Query: 158 AHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTLDEYLTCLLLWVKQRRDLLHL 217
A C NA N+ PVQDCPRMR +QPLTVF++L LKNRTLDEY TCL LWVKQR L+HL
Sbjct: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180
Query: 218 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPILTQFTPYLGHLRNLQKLVLS 277
CCKKLK+LGM F NIR+ILK VNLDCIQEVEVNC W LP+L +FTPYLG +RNL+KLVLS
Sbjct: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTLPVLAEFTPYLGQMRNLRKLVLS 240
Query: 278 HMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLT 337
+D SRY+SPEQKKE VTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQ+LSCLKTSL +L
Sbjct: 241 DID-SRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILA 299
Query: 338 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 397
ITNCVLLESDLKHLS+ PSI QLKTLDLSG RL N+SLVPLQ+LLEKVAATLEYLDLDDC
Sbjct: 300 ITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDC 359
Query: 398 GIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCLELYPAPQESY 457
GI+DSQVNAILPALSRCFEL TFSF GNPI ATLENLL HTI L NLCLELYPAP+ESY
Sbjct: 360 GIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESY 419
Query: 458 GADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPDHGDRSFYDLEADQYCC 513
G +C SRFAQ+ AELM +VR LR P+RILFCTD CP G+RS YDLE D+ CC
Sbjct: 420 DVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRCCC 475
>gi|88942379 PREDICTED: PRAME family member [Homo sapiens]
Length = 395
Score = 748 bits (1931), Expect = 0.0
Identities = 364/381 (95%), Positives = 371/381 (97%)
Query: 133 RRWKLQVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWL 192
RRWKLQVLDLQDVCENFWMVWSEAMA GCFLNAKRNK PVQDCPRMR RQPLTVFVELWL
Sbjct: 15 RRWKLQVLDLQDVCENFWMVWSEAMARGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWL 74
Query: 193 KNRTLDEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCK 252
KNRTLDE+LTCLLLWVKQR+DLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCK
Sbjct: 75 KNRTLDEHLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCK 134
Query: 253 WILPILTQFTPYLGHLRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYM 312
W+LPILTQFTPYLGH+RNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKL CLQKLYM
Sbjct: 135 WVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLHCLQKLYM 194
Query: 313 NSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTN 372
NSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTN
Sbjct: 195 NSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTN 254
Query: 373 YSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATL 432
YSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPI MATL
Sbjct: 255 YSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATL 314
Query: 433 ENLLSHTIILKNLCLELYPAPQESYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCT 492
ENLLSHTIILKNLCLELYPAP+ESYGADGTLCWSRF QIRAELMK+VR LRHPKRILF T
Sbjct: 315 ENLLSHTIILKNLCLELYPAPRESYGADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGT 374
Query: 493 DNCPDHGDRSFYDLEADQYCC 513
D CPD G+RSFYDLEADQYCC
Sbjct: 375 DYCPDCGNRSFYDLEADQYCC 395
>gi|239741047 PREDICTED: PRAME family member 25-like [Homo sapiens]
Length = 474
Score = 661 bits (1705), Expect = 0.0
Identities = 341/477 (71%), Positives = 383/477 (80%), Gaps = 4/477 (0%)
Query: 38 MSIRIPPRLLELXGRSLLRDQALAVSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 97
MS++ P RLLEL G+SLL DQALA+S L+ELP ELFPPLF+EAF+ RRCE LK+MVQAWP
Sbjct: 1 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 60
Query: 98 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 157
F LPL L+K P LE V+DG+D LL Q VRPRR KLQVL+L+DV ENFW +WS A
Sbjct: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 120
Query: 158 AHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTLDEYLTCLLLWVKQRRDLLHL 217
C A + V+DCPR E+QPL VF+++ LK + +DE L+ WV+ RR +HL
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 180
Query: 218 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWILPILTQFTPYLGHLRNLQKLVL 276
CC K+ M N R+IL+ V D IQ +E+ N W I+ +F+PYL +RNL+KL +
Sbjct: 181 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIV-EFSPYLSQMRNLRKLFI 239
Query: 277 SHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVL 336
S D RY+ +E + FTTQFLKL CLQKLYMNSVSFLEGHLDQLLSCLKTSLKVL
Sbjct: 240 S--DGCRYLLSSDSQEQIAPFTTQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVL 297
Query: 337 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 396
TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD
Sbjct: 298 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 357
Query: 397 CGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCLELYPAPQES 456
CGIIDSQVNAILPALSRCFELNTFSFCGNPI MATLENLLSHTIILKNLCLELYPAP+ES
Sbjct: 358 CGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCLELYPAPRES 417
Query: 457 YGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPDHGDRSFYDLEADQYCC 513
YGADGTLCWSRF QIRAELMK+VR LRHPKRILF TD CPD G+RSFYDLEADQYCC
Sbjct: 418 YGADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGTDYCPDCGNRSFYDLEADQYCC 474
>gi|239741053 PREDICTED: similar to Putative PRAME family member 24
[Homo sapiens]
Length = 474
Score = 565 bits (1456), Expect = e-161
Identities = 292/476 (61%), Positives = 353/476 (74%), Gaps = 2/476 (0%)
Query: 38 MSIRIPPRLLELXGRSLLRDQALAVSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 97
MSIR PPRLLEL + LLRDQALA+ST+EELP ELFP LFMEAFSRRRCE LK MVQAWP
Sbjct: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
Query: 98 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 157
F RLPL L+K P LE+ ++VL+G+D LLTQ VRPR+ KLQVLDL++V ENF ++S A
Sbjct: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
Query: 158 AHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTLDEYLTCLLLWVKQRRDLLHL 217
A F A K +CP +QP VF++L LKNRTLDE LT LL W KQR+ LLH+
Sbjct: 121 AS--FPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
Query: 218 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPILTQFTPYLGHLRNLQKLVLS 277
CCK+L++ GMP +I +L MV LDCIQEVEV C W L L +F PYLG +RNL+KLVL
Sbjct: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVLF 238
Query: 278 HMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLT 337
++ S + P+ K + + +FT+QFLKL Q L M+SVSFLEGHLDQLL CL+ SL+++
Sbjct: 239 NIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMVV 298
Query: 338 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 397
+T+C+L ESDLKHLS CPSI QLK LDL G+ LT++S PL LLE+V ATL+ LDL+DC
Sbjct: 299 MTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLEDC 358
Query: 398 GIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCLELYPAPQESY 457
GI+DSQ++AILP LSRC +L+TFSFCGN I MA LENLL HT+ L L LELYPAP ESY
Sbjct: 359 GIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESY 418
Query: 458 GADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPDHGDRSFYDLEADQYCC 513
G LCW RFA++ AELMK +R LR PK I+FCT CP G R+ YDLE C
Sbjct: 419 DTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCLC 474
>gi|59676593 PRAME family member 7 [Homo sapiens]
Length = 474
Score = 564 bits (1453), Expect = e-161
Identities = 292/476 (61%), Positives = 352/476 (73%), Gaps = 2/476 (0%)
Query: 38 MSIRIPPRLLELXGRSLLRDQALAVSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 97
MSIR PPRLLEL + LLRDQALA+ST+EELP ELFP LFMEAFSRRRCE LK MVQAWP
Sbjct: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
Query: 98 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 157
F RLPL L+K P LE+ ++VL+G+D LLTQ VRPR+ KLQVLDL++V ENF ++S A
Sbjct: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
Query: 158 AHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTLDEYLTCLLLWVKQRRDLLHL 217
A F A K +CP +QP VF++L LKNRTLDE LT LL W KQR+ LLH+
Sbjct: 121 AS--FPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
Query: 218 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPILTQFTPYLGHLRNLQKLVLS 277
CCK+L++ GMP +I +L MV LDCIQEVEV C W L L +F PYLG +RNL+KLVL
Sbjct: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVLF 238
Query: 278 HMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLT 337
++ S + P+ K + + +FT+QFLKL Q L M+SVSFLEGHLDQLL CL+ SL+++
Sbjct: 239 NIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMVV 298
Query: 338 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 397
+T+C+L ESDLKHLS CPSI QLK LDL G+ LT++S PL LLE+V ATL+ LDL+DC
Sbjct: 299 MTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLEDC 358
Query: 398 GIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCLELYPAPQESY 457
GI+DSQ++AILP LSRC +L+TFSFCGN I MA LENLL HT+ L L LELYPAP ESY
Sbjct: 359 GIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESY 418
Query: 458 GADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPDHGDRSFYDLEADQYCC 513
G LCW RFA++ AELMK R LR PK I+FCT CP G R+ YDLE C
Sbjct: 419 DTQGALCWGRFAELGAELMKTPRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCLC 474
>gi|59676587 PRAME family member 8 [Homo sapiens]
Length = 474
Score = 563 bits (1452), Expect = e-160
Identities = 291/476 (61%), Positives = 353/476 (74%), Gaps = 2/476 (0%)
Query: 38 MSIRIPPRLLELXGRSLLRDQALAVSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 97
MSIR PPRLLEL + LLRDQALA+ST+EELP ELFP LFMEAFSRRRCE LK MVQAWP
Sbjct: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
Query: 98 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 157
F RLPL L+K P LE+ ++VL+G+D LLTQ VRPR+ KLQVLDL++V ENF ++S A
Sbjct: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
Query: 158 AHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTLDEYLTCLLLWVKQRRDLLHL 217
A F A K +CP +QP VF++L LKNRTLDE LT LL W KQR+ LLH+
Sbjct: 121 AS--FPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
Query: 218 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPILTQFTPYLGHLRNLQKLVLS 277
CC++L++ GMP +I +L MV LDCIQEVEV C W L L +F PYLG +RNL+KLVL
Sbjct: 179 CCQELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVLF 238
Query: 278 HMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLT 337
++ S + P+ K + + +FT+QFLKL Q L M+SVSFLEGHLDQLL CL+ SL+++
Sbjct: 239 NIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMVV 298
Query: 338 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 397
+T+C+L ESDLKHLS CPSI QLK LDL G+ LT++S PL LLE+V ATL+ LDL+DC
Sbjct: 299 MTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLEDC 358
Query: 398 GIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCLELYPAPQESY 457
GI+DSQ++AILP LSRC +L+TFSFCGN I MA LENLL HT+ L L LELYPAP ESY
Sbjct: 359 GIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESY 418
Query: 458 GADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPDHGDRSFYDLEADQYCC 513
G LCW RFA++ AELMK +R LR PK I+FCT CP G R+ YDLE C
Sbjct: 419 DTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCLC 474
>gi|124249372 PRAME family member 12 [Homo sapiens]
Length = 483
Score = 556 bits (1434), Expect = e-158
Identities = 291/470 (61%), Positives = 348/470 (74%), Gaps = 2/470 (0%)
Query: 38 MSIRIPPRLLELXGRSLLRDQALAVSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 97
MS++ PPRLLEL +SLLRD+ALA+ TLEELP ELFPPLFMEAF+RR CE L MVQAWP
Sbjct: 1 MSLQAPPRLLELAEQSLLRDRALAIPTLEELPRELFPPLFMEAFTRRCCETLTTMVQAWP 60
Query: 98 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 157
F LPL L+K LE F+AVL+GLDALL Q VRPRRWKLQVLDL++V ENFW +WS A
Sbjct: 61 FTCLPLGSLMKSCNLEIFRAVLEGLDALLAQKVRPRRWKLQVLDLRNVDENFWGIWSGAS 120
Query: 158 AHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTLDEYLTCLLLWVKQRRDLLHL 217
A +KR +CPR +QPL V ++L KN LDE LT L W KQR+ LLH+
Sbjct: 121 ALSPEALSKRRTAG--NCPRPGGQQPLMVILDLCFKNGMLDECLTHFLEWGKQRKGLLHV 178
Query: 218 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPILTQFTPYLGHLRNLQKLVLS 277
CCK+L+I G+ I +L V LDCIQEVEV C W L IL +F PYLG +RNL+KLVL
Sbjct: 179 CCKELQIFGIAIHRIIEVLNTVELDCIQEVEVCCPWELSILIRFAPYLGQMRNLRKLVLF 238
Query: 278 HMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLT 337
++ VS + ++K++ V QFT+QFLKL QKLYM+SVSFLEGHLDQLL CL+ L+ +
Sbjct: 239 NIHVSACIPLDRKEQFVIQFTSQFLKLDYFQKLYMHSVSFLEGHLDQLLRCLQAPLETVV 298
Query: 338 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 397
+T C+L ESDLKHLS CPSI QLK LDL GI LT++S PL +LLE+ ATL+ LDL+DC
Sbjct: 299 MTECLLSESDLKHLSWCPSIRQLKELDLRGITLTHFSPEPLSVLLEQAEATLQTLDLEDC 358
Query: 398 GIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCLELYPAPQESY 457
GI+DSQ++AILPALSRC +L+TFSFCGN I MA LENLL HT+ L L LELYPAP ESY
Sbjct: 359 GIVDSQLSAILPALSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESY 418
Query: 458 GADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPDHGDRSFYDLE 507
A G LCW RF+Q+ AELMK +R LR PK I+F T CP G R+ YDLE
Sbjct: 419 DAQGALCWGRFSQLGAELMKTLRDLRQPKIIVFSTVPCPRCGIRASYDLE 468
>gi|46249373 preferentially expressed antigen in melanoma [Homo
sapiens]
Length = 509
Score = 436 bits (1121), Expect = e-122
Identities = 241/487 (49%), Positives = 318/487 (65%), Gaps = 13/487 (2%)
Query: 34 RFMKMSIRIPPR-LLELXGRSLLRDQALAVSTLEELPTELFPPLFMEAFSRRRCEALKLM 92
R++ MS+ PR L+EL G+SLL+D+ALA++ LE LP ELFPPLFM AF R + LK M
Sbjct: 13 RYISMSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAM 72
Query: 93 VQAWPFRRLPLRPLIKMPCL--EAFQAVLDGLDALLTQGVRPRRWKLQVLDLQ-DVCENF 149
VQAWPF LPL L+K L E F+AVLDGLD LL Q VRPRRWKLQVLDL+ + ++F
Sbjct: 73 VQAWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDF 132
Query: 150 WMVWSEAMA--------HGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTLDEYL 201
W VWS A K+ K + P+ V V+L+LK DE
Sbjct: 133 WTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELF 192
Query: 202 TCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPILTQF 261
+ L+ VK+++++L LCCKKLKI MP ++I+ ILKMV LD I+++EV C W LP L +F
Sbjct: 193 SYLIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKF 252
Query: 262 TPYLGHLRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGH 321
+PYLG + NL++L+LSH+ S Y+SPE++++ + QFT+QFL L+CLQ LY++S+ FL G
Sbjct: 253 SPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGR 312
Query: 322 LDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQIL 381
LDQLL + L+ L+ITNC L E D+ HLSQ PS+SQL L LSG+ LT+ S PLQ L
Sbjct: 313 LDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQAL 372
Query: 382 LEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTII 441
LE+ +ATL+ L D+CGI D Q+ A+LP+LS C +L T SF GN I ++ L++LL H I
Sbjct: 373 LERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIG 432
Query: 442 LKNLCLELYPAPQESY-GADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPDHGD 500
L NL LYP P ESY GTL R A + A L + + L P + + CP GD
Sbjct: 433 LSNLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGD 492
Query: 501 RSFYDLE 507
R+FYD E
Sbjct: 493 RTFYDPE 499
>gi|46249371 preferentially expressed antigen in melanoma [Homo
sapiens]
Length = 509
Score = 436 bits (1121), Expect = e-122
Identities = 241/487 (49%), Positives = 318/487 (65%), Gaps = 13/487 (2%)
Query: 34 RFMKMSIRIPPR-LLELXGRSLLRDQALAVSTLEELPTELFPPLFMEAFSRRRCEALKLM 92
R++ MS+ PR L+EL G+SLL+D+ALA++ LE LP ELFPPLFM AF R + LK M
Sbjct: 13 RYISMSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAM 72
Query: 93 VQAWPFRRLPLRPLIKMPCL--EAFQAVLDGLDALLTQGVRPRRWKLQVLDLQ-DVCENF 149
VQAWPF LPL L+K L E F+AVLDGLD LL Q VRPRRWKLQVLDL+ + ++F
Sbjct: 73 VQAWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDF 132
Query: 150 WMVWSEAMA--------HGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTLDEYL 201
W VWS A K+ K + P+ V V+L+LK DE
Sbjct: 133 WTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELF 192
Query: 202 TCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPILTQF 261
+ L+ VK+++++L LCCKKLKI MP ++I+ ILKMV LD I+++EV C W LP L +F
Sbjct: 193 SYLIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKF 252
Query: 262 TPYLGHLRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGH 321
+PYLG + NL++L+LSH+ S Y+SPE++++ + QFT+QFL L+CLQ LY++S+ FL G
Sbjct: 253 SPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGR 312
Query: 322 LDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQIL 381
LDQLL + L+ L+ITNC L E D+ HLSQ PS+SQL L LSG+ LT+ S PLQ L
Sbjct: 313 LDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQAL 372
Query: 382 LEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTII 441
LE+ +ATL+ L D+CGI D Q+ A+LP+LS C +L T SF GN I ++ L++LL H I
Sbjct: 373 LERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIG 432
Query: 442 LKNLCLELYPAPQESY-GADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPDHGD 500
L NL LYP P ESY GTL R A + A L + + L P + + CP GD
Sbjct: 433 LSNLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGD 492
Query: 501 RSFYDLE 507
R+FYD E
Sbjct: 493 RTFYDPE 499
>gi|46249369 preferentially expressed antigen in melanoma [Homo
sapiens]
Length = 509
Score = 436 bits (1121), Expect = e-122
Identities = 241/487 (49%), Positives = 318/487 (65%), Gaps = 13/487 (2%)
Query: 34 RFMKMSIRIPPR-LLELXGRSLLRDQALAVSTLEELPTELFPPLFMEAFSRRRCEALKLM 92
R++ MS+ PR L+EL G+SLL+D+ALA++ LE LP ELFPPLFM AF R + LK M
Sbjct: 13 RYISMSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAM 72
Query: 93 VQAWPFRRLPLRPLIKMPCL--EAFQAVLDGLDALLTQGVRPRRWKLQVLDLQ-DVCENF 149
VQAWPF LPL L+K L E F+AVLDGLD LL Q VRPRRWKLQVLDL+ + ++F
Sbjct: 73 VQAWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDF 132
Query: 150 WMVWSEAMA--------HGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTLDEYL 201
W VWS A K+ K + P+ V V+L+LK DE
Sbjct: 133 WTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELF 192
Query: 202 TCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPILTQF 261
+ L+ VK+++++L LCCKKLKI MP ++I+ ILKMV LD I+++EV C W LP L +F
Sbjct: 193 SYLIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKF 252
Query: 262 TPYLGHLRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGH 321
+PYLG + NL++L+LSH+ S Y+SPE++++ + QFT+QFL L+CLQ LY++S+ FL G
Sbjct: 253 SPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGR 312
Query: 322 LDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQIL 381
LDQLL + L+ L+ITNC L E D+ HLSQ PS+SQL L LSG+ LT+ S PLQ L
Sbjct: 313 LDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQAL 372
Query: 382 LEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTII 441
LE+ +ATL+ L D+CGI D Q+ A+LP+LS C +L T SF GN I ++ L++LL H I
Sbjct: 373 LERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIG 432
Query: 442 LKNLCLELYPAPQESY-GADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPDHGD 500
L NL LYP P ESY GTL R A + A L + + L P + + CP GD
Sbjct: 433 LSNLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGD 492
Query: 501 RSFYDLE 507
R+FYD E
Sbjct: 493 RTFYDPE 499
>gi|46249367 preferentially expressed antigen in melanoma [Homo
sapiens]
Length = 509
Score = 436 bits (1121), Expect = e-122
Identities = 241/487 (49%), Positives = 318/487 (65%), Gaps = 13/487 (2%)
Query: 34 RFMKMSIRIPPR-LLELXGRSLLRDQALAVSTLEELPTELFPPLFMEAFSRRRCEALKLM 92
R++ MS+ PR L+EL G+SLL+D+ALA++ LE LP ELFPPLFM AF R + LK M
Sbjct: 13 RYISMSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAM 72
Query: 93 VQAWPFRRLPLRPLIKMPCL--EAFQAVLDGLDALLTQGVRPRRWKLQVLDLQ-DVCENF 149
VQAWPF LPL L+K L E F+AVLDGLD LL Q VRPRRWKLQVLDL+ + ++F
Sbjct: 73 VQAWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDF 132
Query: 150 WMVWSEAMA--------HGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTLDEYL 201
W VWS A K+ K + P+ V V+L+LK DE
Sbjct: 133 WTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELF 192
Query: 202 TCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPILTQF 261
+ L+ VK+++++L LCCKKLKI MP ++I+ ILKMV LD I+++EV C W LP L +F
Sbjct: 193 SYLIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKF 252
Query: 262 TPYLGHLRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGH 321
+PYLG + NL++L+LSH+ S Y+SPE++++ + QFT+QFL L+CLQ LY++S+ FL G
Sbjct: 253 SPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGR 312
Query: 322 LDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQIL 381
LDQLL + L+ L+ITNC L E D+ HLSQ PS+SQL L LSG+ LT+ S PLQ L
Sbjct: 313 LDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQAL 372
Query: 382 LEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTII 441
LE+ +ATL+ L D+CGI D Q+ A+LP+LS C +L T SF GN I ++ L++LL H I
Sbjct: 373 LERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIG 432
Query: 442 LKNLCLELYPAPQESY-GADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPDHGD 500
L NL LYP P ESY GTL R A + A L + + L P + + CP GD
Sbjct: 433 LSNLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGD 492
Query: 501 RSFYDLE 507
R+FYD E
Sbjct: 493 RTFYDPE 499
>gi|5174641 preferentially expressed antigen in melanoma [Homo
sapiens]
Length = 509
Score = 436 bits (1121), Expect = e-122
Identities = 241/487 (49%), Positives = 318/487 (65%), Gaps = 13/487 (2%)
Query: 34 RFMKMSIRIPPR-LLELXGRSLLRDQALAVSTLEELPTELFPPLFMEAFSRRRCEALKLM 92
R++ MS+ PR L+EL G+SLL+D+ALA++ LE LP ELFPPLFM AF R + LK M
Sbjct: 13 RYISMSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAM 72
Query: 93 VQAWPFRRLPLRPLIKMPCL--EAFQAVLDGLDALLTQGVRPRRWKLQVLDLQ-DVCENF 149
VQAWPF LPL L+K L E F+AVLDGLD LL Q VRPRRWKLQVLDL+ + ++F
Sbjct: 73 VQAWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDF 132
Query: 150 WMVWSEAMA--------HGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTLDEYL 201
W VWS A K+ K + P+ V V+L+LK DE
Sbjct: 133 WTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELF 192
Query: 202 TCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPILTQF 261
+ L+ VK+++++L LCCKKLKI MP ++I+ ILKMV LD I+++EV C W LP L +F
Sbjct: 193 SYLIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKF 252
Query: 262 TPYLGHLRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGH 321
+PYLG + NL++L+LSH+ S Y+SPE++++ + QFT+QFL L+CLQ LY++S+ FL G
Sbjct: 253 SPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGR 312
Query: 322 LDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQIL 381
LDQLL + L+ L+ITNC L E D+ HLSQ PS+SQL L LSG+ LT+ S PLQ L
Sbjct: 313 LDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQAL 372
Query: 382 LEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTII 441
LE+ +ATL+ L D+CGI D Q+ A+LP+LS C +L T SF GN I ++ L++LL H I
Sbjct: 373 LERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIG 432
Query: 442 LKNLCLELYPAPQESY-GADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPDHGD 500
L NL LYP P ESY GTL R A + A L + + L P + + CP GD
Sbjct: 433 LSNLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGD 492
Query: 501 RSFYDLE 507
R+FYD E
Sbjct: 493 RTFYDPE 499
>gi|154800493 PRAME family member 22 [Homo sapiens]
Length = 481
Score = 420 bits (1079), Expect = e-117
Identities = 237/474 (50%), Positives = 309/474 (65%), Gaps = 5/474 (1%)
Query: 36 MKMSIRIPPRLLELXGRSLLRDQALAVSTLEELPTELFPPLFMEAFSRRRCEALKLMVQA 95
M+MS++ P RLLEL G+SLL DQALA+S L+ELP ELFPPLF+EAF+ RRCE LK+MVQA
Sbjct: 1 MRMSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQA 60
Query: 96 WPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSE 155
WPF LPL L+K P LE V+DG+D LL Q VRPRRWKLQVL+L+DV ENFW +WS
Sbjct: 61 WPFPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSG 120
Query: 156 AMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTLDEYLTCLLLWVKQRRDLL 215
A C A + V+DCPR E+QPL VF+++ LK + +DE L+ WV+ RR +
Sbjct: 121 ARPLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSV 180
Query: 216 HLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWILPILTQFTPYLGHLRNLQKL 274
HLCC K+ M N R+IL+ V D IQ +E+ N W ++ +F+ YL +RNL+KL
Sbjct: 181 HLCCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPC-MIVEFSRYLSQMRNLRKL 239
Query: 275 VLSHMDVSRY-VSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSL 333
+S D RY +S + ++++V +F++ L+L LQ LY+ V F GHLDQL+ CL++ L
Sbjct: 240 FIS--DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPL 297
Query: 334 KVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLD 393
+ L +T L + DLK L + PS+SQLK L+LS L L PL+ LLEKVAATL+ L
Sbjct: 298 ETLALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLF 357
Query: 394 LDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCLELYPAP 453
L DCGI DS++ ILPALS C L TF F GN M L++LL HT L NL LE YPAP
Sbjct: 358 LVDCGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAP 417
Query: 454 QESYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPDHGDRSFYDLE 507
+ES G + ++AELM+ +R +R PKRI F +CP G LE
Sbjct: 418 RESLDDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLE 471
>gi|194306638 PRAME family member 3 [Homo sapiens]
Length = 481
Score = 414 bits (1063), Expect = e-115
Identities = 236/474 (49%), Positives = 307/474 (64%), Gaps = 5/474 (1%)
Query: 36 MKMSIRIPPRLLELXGRSLLRDQALAVSTLEELPTELFPPLFMEAFSRRRCEALKLMVQA 95
M+MS++ P RLLEL G+SLL DQALA+S L+ELP ELFPPLF+EAF+ RRCE LK+MVQA
Sbjct: 1 MRMSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQA 60
Query: 96 WPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSE 155
WPF LPL L+K P LE V+DG+D LL Q VRPRR KLQVL+L+DV ENFW +WS
Sbjct: 61 WPFPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSG 120
Query: 156 AMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTLDEYLTCLLLWVKQRRDLL 215
A C A + V+DCPR E+QPL VF+++ LK + +DE L+ WV+ RR +
Sbjct: 121 ARPLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSV 180
Query: 216 HLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWILPILTQFTPYLGHLRNLQKL 274
HLCC K+ M N R+IL+ V D IQ +E+ N W ++ +F YL +RNL+KL
Sbjct: 181 HLCCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPC-MIVEFIRYLSQMRNLRKL 239
Query: 275 VLSHMDVSRY-VSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSL 333
+S D RY +S + ++++V +F++ L+L LQ LY+ V F GHLDQL+ CL++ L
Sbjct: 240 FIS--DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPL 297
Query: 334 KVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLD 393
+ L +T L + DLK L + PS+SQLK L+LS L L PL+ LLEKVAATL+ L
Sbjct: 298 ETLALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLF 357
Query: 394 LDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCLELYPAP 453
L DCGI DS++ ILPALS C L TF F GN M L++LL HT L NL LE YPAP
Sbjct: 358 LVDCGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAP 417
Query: 454 QESYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPDHGDRSFYDLE 507
+ES G + ++AELM+ +R +R PKRI F +CP G LE
Sbjct: 418 RESLDDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLE 471
>gi|153791443 PRAME family member 18 [Homo sapiens]
Length = 479
Score = 412 bits (1058), Expect = e-115
Identities = 233/461 (50%), Positives = 302/461 (65%), Gaps = 5/461 (1%)
Query: 38 MSIRIPPRLLELXGRSLLRDQALAVSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 97
MS + P RLLEL G+SLLRDQALA+S L+ELP ELFP LF+EAF+ RRCE LK+MVQAWP
Sbjct: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
Query: 98 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 157
F LPL L+K P LE V+DG+D LL Q VRPRRWKLQVL+++DV ENFW +WS A
Sbjct: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
Query: 158 AHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTLDEYLTCLLLWVKQRRDLLHL 217
C A + V+DCPR E+QPL VF+++ LK +++DE L+ WV+ RR +HL
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
Query: 218 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWILPILTQFTPYLGHLRNLQKLVL 276
CC K+ M N R+IL+ V D IQ +E+ N W ++ + + YL ++NL+KL +
Sbjct: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPC-MVAEVSRYLSQMKNLRKLFI 239
Query: 277 SHMDVSRYV-SPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKV 335
S D Y+ S E + ++V +F++ FL+L LQ LYM + F EG+LDQL+ CLK+ L+
Sbjct: 240 S--DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLET 297
Query: 336 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 395
L +T L E DLK L PS+SQLK L+LS L L PL+ LLEKVAATL+ L L
Sbjct: 298 LALTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLV 357
Query: 396 DCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCLELYPAPQE 455
DCGI DS++ ILPALSRC L TF F GN M L++LL HT L NL LE YPAP+E
Sbjct: 358 DCGIGDSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRE 417
Query: 456 SYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCP 496
S G + ++AELM+ +R +R P RI F +CP
Sbjct: 418 SLDNRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCP 458
>gi|194306635 PRAME family member 19 [Homo sapiens]
Length = 479
Score = 408 bits (1049), Expect = e-114
Identities = 232/461 (50%), Positives = 301/461 (65%), Gaps = 5/461 (1%)
Query: 38 MSIRIPPRLLELXGRSLLRDQALAVSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 97
MS + P RLLEL G+SLLRDQALA+S L+ELP ELFP LF+EAF+ RRCE LK+MVQAWP
Sbjct: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
Query: 98 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 157
F LPL L+K P LE V+DG+D LL Q VRPRRWKLQVL+++DV ENFW +WS A
Sbjct: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
Query: 158 AHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTLDEYLTCLLLWVKQRRDLLHL 217
C A + V+DCPR E+QPL VF+++ LK +++DE L+ WV+ RR +HL
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
Query: 218 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWILPILTQFTPYLGHLRNLQKLVL 276
CC K+ M N R+IL+ V D IQ +E+ N W ++ + + YL ++NL+KL +
Sbjct: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPC-MVAEVSRYLSQMKNLRKLFI 239
Query: 277 SHMDVSRYV-SPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKV 335
S D Y+ S E + ++V +F++ FL+L LQ LYM + F EG+LDQL+ CLK+ L+
Sbjct: 240 S--DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLET 297
Query: 336 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 395
L +T L E DLK L PS+SQLK L+LS L L PL+ LLEKVAATL+ L L
Sbjct: 298 LALTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLV 357
Query: 396 DCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCLELYPAPQE 455
DCGI S++ ILPALSRC L TF F GN M L++LL HT L NL LE YPAP+E
Sbjct: 358 DCGIGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRE 417
Query: 456 SYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCP 496
S G + ++AELM+ +R +R P RI F +CP
Sbjct: 418 SLDNRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCP 458
>gi|113865933 PRAME family member 16 [Homo sapiens]
Length = 474
Score = 407 bits (1045), Expect = e-113
Identities = 235/463 (50%), Positives = 287/463 (61%), Gaps = 3/463 (0%)
Query: 38 MSIRIPPRLLELXGRSLLRDQALAVSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 97
MS++ P RLLEL G+SLLR+Q L + L+ELP E+FP +FMEA S R EALKLMVQAWP
Sbjct: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
Query: 98 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 157
F RLPL L+K P LE QAVL GLD LL Q +RPRRWKLQVLDL+DV NFW +WS A
Sbjct: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
Query: 158 AHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTLDEYLTCLLLWVKQRRDLLHL 217
A C A R + V+D PR E QPL VF++L K TLDE L+ L W+ RR L+HL
Sbjct: 121 ALSCSPEAMRKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
Query: 218 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPILTQFTPYLGHLRNLQKLVLS 277
CC K++ MP + R++LK V D IQE+E+ K L +F PYL + NL+KL L+
Sbjct: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
Query: 278 H-MDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVL 336
D YVS +Q + V FL L Q LY+ +S ++ HL+ LL CLK L
Sbjct: 241 FGYDDELYVSGQQ--QFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTF 298
Query: 337 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 396
+ L + D++ LSQ PS+SQLK L L I + +L PL LLEKVAATLE L L D
Sbjct: 299 IFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKD 358
Query: 397 CGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCLELYPAPQES 456
C I DSQ+ +LPALSRC +L TF F GN L++LL HT L L LELYPAP E
Sbjct: 359 CQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLEC 418
Query: 457 YGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPDHG 499
G + W A IRAELM +R +R PKRI F CP G
Sbjct: 419 LDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCG 461
>gi|157426839 PRAME family member 17 [Homo sapiens]
Length = 474
Score = 404 bits (1039), Expect = e-113
Identities = 234/463 (50%), Positives = 286/463 (61%), Gaps = 3/463 (0%)
Query: 38 MSIRIPPRLLELXGRSLLRDQALAVSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 97
MS++ P RLLEL G+SLLR+Q L + L+ELP E+FP +FMEA S R EALKLMVQAWP
Sbjct: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
Query: 98 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 157
F RLPL L+K P LE QAVL GLD LL Q +RPRRWKLQVLDL+DV NFW +WS A
Sbjct: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
Query: 158 AHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTLDEYLTCLLLWVKQRRDLLHL 217
A C A + V+D PR E QPL VF++L K TLDE L+ L W+ RR L+HL
Sbjct: 121 ALSCSPEAMSKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
Query: 218 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPILTQFTPYLGHLRNLQKLVLS 277
CC K++ MP + R++LK V D IQE+E+ K L +F PYL + NL+KL L+
Sbjct: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
Query: 278 H-MDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVL 336
D YVS +Q + V FL L Q LY+ +S ++ HL+ LL CLK L
Sbjct: 241 FGYDDELYVSGQQ--QFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTF 298
Query: 337 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 396
+ L + D++ LSQ PS+SQLK L L I + +L PL LLEKVAATLE L L D
Sbjct: 299 IFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKD 358
Query: 397 CGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCLELYPAPQES 456
C I DSQ+ +LPALSRC +L TF F GN L++LL HT L L LELYPAP E
Sbjct: 359 CQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLEC 418
Query: 457 YGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPDHG 499
G + W A IRAELM +R +R PKRI F CP G
Sbjct: 419 LDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCG 461
>gi|66954681 PRAME family member 13 [Homo sapiens]
Length = 474
Score = 404 bits (1037), Expect = e-112
Identities = 232/477 (48%), Positives = 300/477 (62%), Gaps = 4/477 (0%)
Query: 38 MSIRIPPRLLELXGRSLLRDQALAVSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 97
MSI+ PPRLLEL G+SLLRDQAL++S +EELP L+ PLFMEAF RR + L +MVQAWP
Sbjct: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
Query: 98 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 157
F LPL L+K LE +A+L+GL LLTQ RPRRWKLQVLDL+DV ENFW W A
Sbjct: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
Query: 158 AHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTLDEYLTCLLLWVKQRRDLLHL 217
A CF + +DCPRM E QPL VF+++ LK DE L L WV QRR L+HL
Sbjct: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
Query: 218 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWILPILTQFTPYLGHLRNLQKLVL 276
CC KL P +++R LK++ L+ IQ++E+ N W ++ + YL ++NL+KLV
Sbjct: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSW-PRLIRKLRCYLKEMKNLRKLVF 239
Query: 277 SHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVL 336
S S E + +VT+F++ FL+L LQ L + ++F GHL+QL+ CL+ L+ L
Sbjct: 240 SRCHHS-MSDNELEGRLVTKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENL 298
Query: 337 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 396
+T LLE D+K LSQ PS+ LK L+LS + L SL PL LLEK+AA+LE L L+
Sbjct: 299 ELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEG 358
Query: 397 CGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCLELYPAPQES 456
C I SQ++AILP LS C +L TF F N + M L++LL HT L L LE YPAP+ES
Sbjct: 359 CQIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLRHTSGLSKLSLETYPAPEES 418
Query: 457 YGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPDHGDRSFYDLEADQYCC 513
+ + W FA +RAELM +R +R PKRI CP G +LE CC
Sbjct: 419 LNSLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELEL-HLCC 474
>gi|12738831 PRAME family member 1 [Homo sapiens]
Length = 474
Score = 402 bits (1034), Expect = e-112
Identities = 233/478 (48%), Positives = 301/478 (62%), Gaps = 6/478 (1%)
Query: 38 MSIRIPPRLLELXGRSLLRDQALAVSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 97
MSI+ PPRLLEL G+SLLRDQAL++S +EELP L+ PLFMEAFSRR + L +MVQAWP
Sbjct: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFSRRHFQTLTVMVQAWP 60
Query: 98 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 157
F LPL L+K LE +A+L+GL LLTQ RPRRWKLQVLDL+DV ENFW W A
Sbjct: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
Query: 158 AHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTLDEYLTCLLLWVKQRRDLLHL 217
A CF + +DCPRM E QPL VF+++ LK DE L L WV QRR L+HL
Sbjct: 121 ALSCFPETTSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
Query: 218 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWILPILTQFTPYLGHLRNLQKLVL 276
CC KL P + +R LK++ L+ IQE+E+ N W ++ + YL ++NL+KLV
Sbjct: 181 CCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNMSW-PRLIRKLRCYLKEMKNLRKLVF 239
Query: 277 SHMDVSRYVSP-EQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKV 335
S Y S E + +V +F++ FL+L LQ L + ++F GHL+QL+ CL+ L+
Sbjct: 240 SR--CHHYTSDNELQGRLVAKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLEN 297
Query: 336 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 395
L +T LLE D+K LSQ PS+ LK L+LS + L SL PL LLEK+AA+L+ L L+
Sbjct: 298 LELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLKTLILE 357
Query: 396 DCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCLELYPAPQE 455
C I SQ++AILPALSRC +L TF F N + + L++LL HT L L LE YPAP+E
Sbjct: 358 GCQIHYSQLSAILPALSRCSQLTTFYFGRNCMSIDALKDLLRHTSGLSKLSLETYPAPEE 417
Query: 456 SYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPDHGDRSFYDLEADQYCC 513
S + + W F +RAELM +R +R PKRI CP G +LE CC
Sbjct: 418 SLNSLVRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELEL-HLCC 474
>gi|194018546 PRAME family member 10 [Homo sapiens]
Length = 474
Score = 402 bits (1032), Expect = e-112
Identities = 230/463 (49%), Positives = 291/463 (62%), Gaps = 3/463 (0%)
Query: 38 MSIRIPPRLLELXGRSLLRDQALAVSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 97
MS++ P RLLEL G+SLLR+Q L + TL+ELP E+FP +FMEAFS RR EALKLMVQAWP
Sbjct: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
Query: 98 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 157
F LPL L+K LE QAVL GLD L+ Q VRPRRWKLQVLDL+DV ENFW +WS A
Sbjct: 61 FLSLPLGSLMKTLHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
Query: 158 AHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTLDEYLTCLLLWVKQRRDLLHL 217
C A + V+DCPRM E QPL VF++L LK TLDE L+ L W+ RR L+HL
Sbjct: 121 VLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
Query: 218 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPILTQFTPYLGHLRNLQKLVLS 277
CC K++ MP + R++L+ + D IQE+EV K L +F PYL + NL++L L+
Sbjct: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLA 240
Query: 278 H-MDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVL 336
+ YVS + + + FL L Q LY+ +S ++ HL+ LL LK L
Sbjct: 241 FGYERELYVSVQW--PCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAF 298
Query: 337 TITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDD 396
++ L + D++ LSQ PS+SQLK L L I + L PL +LLEKVAATL+ L L D
Sbjct: 299 IFSDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKD 358
Query: 397 CGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCLELYPAPQES 456
C I D Q+ +LPALS C +L TF+F GN M L++LL HT L L LELYPAP ES
Sbjct: 359 CRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTGGLSKLGLELYPAPLES 418
Query: 457 YGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPDHG 499
G + W IRAELM+ +R +R PKRI F CP+ G
Sbjct: 419 LDYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPNCG 461
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.328 0.141 0.450
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,670,042
Number of Sequences: 37866
Number of extensions: 845678
Number of successful extensions: 2255
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 49
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 2123
Number of HSP's gapped (non-prelim): 80
length of query: 513
length of database: 18,247,518
effective HSP length: 107
effective length of query: 406
effective length of database: 14,195,856
effective search space: 5763517536
effective search space used: 5763517536
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.