Guide to the Human Genome
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Search of human proteins with 239740684

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239740684 PREDICTED: similar to C4A protein isoform 1 [Homo
sapiens]
         (1744 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239740684 PREDICTED: similar to C4A protein isoform 1 [Homo s...  3487   0.0  
gi|67190748 complement component 4A preproprotein [Homo sapiens]     3477   0.0  
gi|178557739 complement component 4B preproprotein [Homo sapiens]    3457   0.0  
gi|239740686 PREDICTED: similar to C4A protein isoform 2 [Homo s...  3374   0.0  
gi|239758130 PREDICTED: similar to complement component 4B (Chil...  1318   0.0  
gi|115298678 complement component 3 precursor [Homo sapiens]          636   0.0  
gi|239754277 PREDICTED: similar to Complement component 4A (Rodg...   531   e-150
gi|169218213 PREDICTED: similar to complement component C3, part...   520   e-147
gi|38016947 complement component 5 preproprotein [Homo sapiens]       517   e-146
gi|66932947 alpha-2-macroglobulin precursor [Homo sapiens]            296   9e-80
gi|227430303 CD109 antigen isoform 3 precursor [Homo sapiens]         239   2e-62
gi|115529484 CD109 antigen isoform 1 precursor [Homo sapiens]         239   2e-62
gi|162809334 pregnancy-zone protein [Homo sapiens]                    236   1e-61
gi|118600977 C3 and PZP-like, alpha-2-macroglobulin domain conta...   235   2e-61
gi|74271845 alpha-2-macroglobulin-like 1 [Homo sapiens]               216   2e-55
gi|227430301 CD109 antigen isoform 2 precursor [Homo sapiens]         208   4e-53
gi|239744583 PREDICTED: ovostatin 2 [Homo sapiens]                    135   3e-31
gi|169204289 PREDICTED: ovostatin [Homo sapiens]                      132   4e-30
gi|169214179 PREDICTED: similar to complement component 3 [Homo ...   128   4e-29
gi|239750255 PREDICTED: similar to ovostatin-2 [Homo sapiens]          69   3e-11
gi|169217711 PREDICTED: similar to Ovostatin homolog 2 [Homo sap...    57   2e-07
gi|239755748 PREDICTED: ovostatin [Homo sapiens]                       53   3e-06
gi|169205183 PREDICTED: similar to hCG38149 [Homo sapiens]             50   2e-05
gi|239744557 PREDICTED: hypothetical protein LOC728715 [Homo sap...    50   2e-05
gi|239755754 PREDICTED: ovostatin 2 [Homo sapiens]                     38   0.075
gi|21359951 RNA binding motif protein 42 [Homo sapiens]                38   0.075
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap...    33   2.4  
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap...    33   2.4  
gi|109689723 abl interactor 2 [Homo sapiens]                           33   2.4  
gi|120587027 ubiquitin specific peptidase 31 [Homo sapiens]            33   2.4  

>gi|239740684 PREDICTED: similar to C4A protein isoform 1 [Homo
            sapiens]
          Length = 1744

 Score = 3487 bits (9041), Expect = 0.0
 Identities = 1744/1744 (100%), Positives = 1744/1744 (100%)

Query: 1    MRLLWGLIWASSFFTLSLQKPRLLLFSPSVVHLGVPLSVGVQLQDVPRGQVVKGSVFLRN 60
            MRLLWGLIWASSFFTLSLQKPRLLLFSPSVVHLGVPLSVGVQLQDVPRGQVVKGSVFLRN
Sbjct: 1    MRLLWGLIWASSFFTLSLQKPRLLLFSPSVVHLGVPLSVGVQLQDVPRGQVVKGSVFLRN 60

Query: 61   PSRNNVPCSPKVDFTLSSERDFALLSLQVPLKDAKSCGLHQLLRGPEVQLVAHSPWLKDS 120
            PSRNNVPCSPKVDFTLSSERDFALLSLQVPLKDAKSCGLHQLLRGPEVQLVAHSPWLKDS
Sbjct: 61   PSRNNVPCSPKVDFTLSSERDFALLSLQVPLKDAKSCGLHQLLRGPEVQLVAHSPWLKDS 120

Query: 121  LSRTTNIQGINLLFSSRRGHLFLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTITVMVEN 180
            LSRTTNIQGINLLFSSRRGHLFLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTITVMVEN
Sbjct: 121  LSRTTNIQGINLLFSSRRGHLFLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTITVMVEN 180

Query: 181  SHGLRVRKKEVYMPSSIFQDDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPN 240
            SHGLRVRKKEVYMPSSIFQDDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPN
Sbjct: 181  SHGLRVRKKEVYMPSSIFQDDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPN 240

Query: 241  FEVKITPGKPYILTVPGHLDEMQLDIQARYIYGKPVQGVAYVRFGLLDEDGKKTFFRGLE 300
            FEVKITPGKPYILTVPGHLDEMQLDIQARYIYGKPVQGVAYVRFGLLDEDGKKTFFRGLE
Sbjct: 241  FEVKITPGKPYILTVPGHLDEMQLDIQARYIYGKPVQGVAYVRFGLLDEDGKKTFFRGLE 300

Query: 301  SQTKLVNGQSHISLSKAEFQDALEKLNMGITDLQGLRLYVAAAIIEYPGGEMEEAELTSW 360
            SQTKLVNGQSHISLSKAEFQDALEKLNMGITDLQGLRLYVAAAIIEYPGGEMEEAELTSW
Sbjct: 301  SQTKLVNGQSHISLSKAEFQDALEKLNMGITDLQGLRLYVAAAIIEYPGGEMEEAELTSW 360

Query: 361  YFVSSPFSLDLSKTKRHLVPGAPFLLQALVREMSGSPASGIPVKVSATVSSPGSVPEVQD 420
            YFVSSPFSLDLSKTKRHLVPGAPFLLQALVREMSGSPASGIPVKVSATVSSPGSVPEVQD
Sbjct: 361  YFVSSPFSLDLSKTKRHLVPGAPFLLQALVREMSGSPASGIPVKVSATVSSPGSVPEVQD 420

Query: 421  IQQNTDGSGQVSIPIIIPQTISELQLSVSAGSPHPAIARLTVAAPPSGGPGFLSIEWPDS 480
            IQQNTDGSGQVSIPIIIPQTISELQLSVSAGSPHPAIARLTVAAPPSGGPGFLSIEWPDS
Sbjct: 421  IQQNTDGSGQVSIPIIIPQTISELQLSVSAGSPHPAIARLTVAAPPSGGPGFLSIEWPDS 480

Query: 481  RPPRVGDTLNLNLRAVGSGATFSHYYYMILSRGQIVFMNREPKRTLTSVSVFVDHHLAPS 540
            RPPRVGDTLNLNLRAVGSGATFSHYYYMILSRGQIVFMNREPKRTLTSVSVFVDHHLAPS
Sbjct: 481  RPPRVGDTLNLNLRAVGSGATFSHYYYMILSRGQIVFMNREPKRTLTSVSVFVDHHLAPS 540

Query: 541  FYFVAFYYHGDHPVANSLRVDVQAGACEGKLELSVDGAKQYRNGESVKLHLETDSLALVA 600
            FYFVAFYYHGDHPVANSLRVDVQAGACEGKLELSVDGAKQYRNGESVKLHLETDSLALVA
Sbjct: 541  FYFVAFYYHGDHPVANSLRVDVQAGACEGKLELSVDGAKQYRNGESVKLHLETDSLALVA 600

Query: 601  LGALDTALYAAGSKSHKPLNMGKVFEAMNSYDLGCGPGGGDSALQVFQAAGLAFSDGDQW 660
            LGALDTALYAAGSKSHKPLNMGKVFEAMNSYDLGCGPGGGDSALQVFQAAGLAFSDGDQW
Sbjct: 601  LGALDTALYAAGSKSHKPLNMGKVFEAMNSYDLGCGPGGGDSALQVFQAAGLAFSDGDQW 660

Query: 661  TLSRKRLSCPKEKTTRKKRNVNFQKAINEKLGQYASPTAKRCCQDGVTRLPMMRSCEQRA 720
            TLSRKRLSCPKEKTTRKKRNVNFQKAINEKLGQYASPTAKRCCQDGVTRLPMMRSCEQRA
Sbjct: 661  TLSRKRLSCPKEKTTRKKRNVNFQKAINEKLGQYASPTAKRCCQDGVTRLPMMRSCEQRA 720

Query: 721  ARVQQPDCREPFLSCCQFAESLRKKSRDKGQAGLQRALEILQEEDLIDEDDIPVRSFFPE 780
            ARVQQPDCREPFLSCCQFAESLRKKSRDKGQAGLQRALEILQEEDLIDEDDIPVRSFFPE
Sbjct: 721  ARVQQPDCREPFLSCCQFAESLRKKSRDKGQAGLQRALEILQEEDLIDEDDIPVRSFFPE 780

Query: 781  NWLWRVETVDRFQILTLWLPDSLTTWEIHGLSLSKTKGLCVATPVQLRVFREFHLHLRLP 840
            NWLWRVETVDRFQILTLWLPDSLTTWEIHGLSLSKTKGLCVATPVQLRVFREFHLHLRLP
Sbjct: 781  NWLWRVETVDRFQILTLWLPDSLTTWEIHGLSLSKTKGLCVATPVQLRVFREFHLHLRLP 840

Query: 841  MSVRRFEQLELRPVLYNYLDKNLTVSVHVSPVEGLCLAGGGGLAQQVLVPAGSARPVAFS 900
            MSVRRFEQLELRPVLYNYLDKNLTVSVHVSPVEGLCLAGGGGLAQQVLVPAGSARPVAFS
Sbjct: 841  MSVRRFEQLELRPVLYNYLDKNLTVSVHVSPVEGLCLAGGGGLAQQVLVPAGSARPVAFS 900

Query: 901  VVPTAAAAVSLKVVARGSFEFPVGDAVSKVLQIEKEGAIHREELVYELNPLDHRGRTLEI 960
            VVPTAAAAVSLKVVARGSFEFPVGDAVSKVLQIEKEGAIHREELVYELNPLDHRGRTLEI
Sbjct: 901  VVPTAAAAVSLKVVARGSFEFPVGDAVSKVLQIEKEGAIHREELVYELNPLDHRGRTLEI 960

Query: 961  PGNSDPNMIPDGDFNSYVRVTASDPLDTLGSEGALSPGGVASLLRLPRGCGEQTMIYLAP 1020
            PGNSDPNMIPDGDFNSYVRVTASDPLDTLGSEGALSPGGVASLLRLPRGCGEQTMIYLAP
Sbjct: 961  PGNSDPNMIPDGDFNSYVRVTASDPLDTLGSEGALSPGGVASLLRLPRGCGEQTMIYLAP 1020

Query: 1021 TLAASRYLDKTEQWSTLPPETKDHAVDLIQKGYMRIQQFRKADGSYAAWLSRDSSTWLTA 1080
            TLAASRYLDKTEQWSTLPPETKDHAVDLIQKGYMRIQQFRKADGSYAAWLSRDSSTWLTA
Sbjct: 1021 TLAASRYLDKTEQWSTLPPETKDHAVDLIQKGYMRIQQFRKADGSYAAWLSRDSSTWLTA 1080

Query: 1081 FVLKVLSLAQEQVGGSPEKLQETSNWLLSQQQADGSFQDPCPVLDRSMQGGLVGNDETVA 1140
            FVLKVLSLAQEQVGGSPEKLQETSNWLLSQQQADGSFQDPCPVLDRSMQGGLVGNDETVA
Sbjct: 1081 FVLKVLSLAQEQVGGSPEKLQETSNWLLSQQQADGSFQDPCPVLDRSMQGGLVGNDETVA 1140

Query: 1141 LTAFVTIALHHGLAVFQDEGAEPLKQRVEASISKANSFLGEKASAGLLGAHAAAITAYAL 1200
            LTAFVTIALHHGLAVFQDEGAEPLKQRVEASISKANSFLGEKASAGLLGAHAAAITAYAL
Sbjct: 1141 LTAFVTIALHHGLAVFQDEGAEPLKQRVEASISKANSFLGEKASAGLLGAHAAAITAYAL 1200

Query: 1201 TLTKAPVDLLGVAHNNLMAMAQETGDNLYWGSVTGSQSNAVSPTPAPRNPSDPMPQAPAL 1260
            TLTKAPVDLLGVAHNNLMAMAQETGDNLYWGSVTGSQSNAVSPTPAPRNPSDPMPQAPAL
Sbjct: 1201 TLTKAPVDLLGVAHNNLMAMAQETGDNLYWGSVTGSQSNAVSPTPAPRNPSDPMPQAPAL 1260

Query: 1261 WIETTAYALLHLLLHEGKAEMADQAAAWLTRQGSFQGGFRSTQDTVIALDALSAYWIASH 1320
            WIETTAYALLHLLLHEGKAEMADQAAAWLTRQGSFQGGFRSTQDTVIALDALSAYWIASH
Sbjct: 1261 WIETTAYALLHLLLHEGKAEMADQAAAWLTRQGSFQGGFRSTQDTVIALDALSAYWIASH 1320

Query: 1321 TTEERGLNVTLSSTGRNGFKSHALQLNNRQIRGLEEELQFSLGSKINVKVGGNSKGTLKV 1380
            TTEERGLNVTLSSTGRNGFKSHALQLNNRQIRGLEEELQFSLGSKINVKVGGNSKGTLKV
Sbjct: 1321 TTEERGLNVTLSSTGRNGFKSHALQLNNRQIRGLEEELQFSLGSKINVKVGGNSKGTLKV 1380

Query: 1381 LRTYNVLDMKNTTCQDLQIEVTVKGHVEYTMEANEDYEDYEYDELPAKDDPDAPLQPVTP 1440
            LRTYNVLDMKNTTCQDLQIEVTVKGHVEYTMEANEDYEDYEYDELPAKDDPDAPLQPVTP
Sbjct: 1381 LRTYNVLDMKNTTCQDLQIEVTVKGHVEYTMEANEDYEDYEYDELPAKDDPDAPLQPVTP 1440

Query: 1441 LQLFEGRRNRRRREAPKVVEEQESRVHYTVCIWRNGKVGLSGMAIADVTLLSGFHALRAD 1500
            LQLFEGRRNRRRREAPKVVEEQESRVHYTVCIWRNGKVGLSGMAIADVTLLSGFHALRAD
Sbjct: 1441 LQLFEGRRNRRRREAPKVVEEQESRVHYTVCIWRNGKVGLSGMAIADVTLLSGFHALRAD 1500

Query: 1501 LEKLTSLSDRYVSHFETEGPHVLLYFDSVPTSRECVGFEAVQEVPVGLVQPASATLYDYY 1560
            LEKLTSLSDRYVSHFETEGPHVLLYFDSVPTSRECVGFEAVQEVPVGLVQPASATLYDYY
Sbjct: 1501 LEKLTSLSDRYVSHFETEGPHVLLYFDSVPTSRECVGFEAVQEVPVGLVQPASATLYDYY 1560

Query: 1561 NPERRCSVFYGAPSKSRLLATLCSAEVCQCAEGKCPRQRRALERGLQDEDGYRMKFACYY 1620
            NPERRCSVFYGAPSKSRLLATLCSAEVCQCAEGKCPRQRRALERGLQDEDGYRMKFACYY
Sbjct: 1561 NPERRCSVFYGAPSKSRLLATLCSAEVCQCAEGKCPRQRRALERGLQDEDGYRMKFACYY 1620

Query: 1621 PRVEYGFQVKVLREDSRAAFRLFETKITQVLHFTKDVKAAANQMRNFLVRASCRLRLEPG 1680
            PRVEYGFQVKVLREDSRAAFRLFETKITQVLHFTKDVKAAANQMRNFLVRASCRLRLEPG
Sbjct: 1621 PRVEYGFQVKVLREDSRAAFRLFETKITQVLHFTKDVKAAANQMRNFLVRASCRLRLEPG 1680

Query: 1681 KEYLIMGLDGATYDLEGHPQYLLDSNSWIEEMPSERLCRSTRQRAACAQLNDFLQEYGTQ 1740
            KEYLIMGLDGATYDLEGHPQYLLDSNSWIEEMPSERLCRSTRQRAACAQLNDFLQEYGTQ
Sbjct: 1681 KEYLIMGLDGATYDLEGHPQYLLDSNSWIEEMPSERLCRSTRQRAACAQLNDFLQEYGTQ 1740

Query: 1741 GCQV 1744
            GCQV
Sbjct: 1741 GCQV 1744


>gi|67190748 complement component 4A preproprotein [Homo sapiens]
          Length = 1744

 Score = 3477 bits (9015), Expect = 0.0
 Identities = 1741/1744 (99%), Positives = 1742/1744 (99%)

Query: 1    MRLLWGLIWASSFFTLSLQKPRLLLFSPSVVHLGVPLSVGVQLQDVPRGQVVKGSVFLRN 60
            MRLLWGLIWASSFFTLSLQKPRLLLFSPSVVHLGVPLSVGVQLQDVPRGQVVKGSVFLRN
Sbjct: 1    MRLLWGLIWASSFFTLSLQKPRLLLFSPSVVHLGVPLSVGVQLQDVPRGQVVKGSVFLRN 60

Query: 61   PSRNNVPCSPKVDFTLSSERDFALLSLQVPLKDAKSCGLHQLLRGPEVQLVAHSPWLKDS 120
            PSRNNVPCSPKVDFTLSSERDFALLSLQVPLKDAKSCGLHQLLRGPEVQLVAHSPWLKDS
Sbjct: 61   PSRNNVPCSPKVDFTLSSERDFALLSLQVPLKDAKSCGLHQLLRGPEVQLVAHSPWLKDS 120

Query: 121  LSRTTNIQGINLLFSSRRGHLFLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTITVMVEN 180
            LSRTTNIQGINLLFSSRRGHLFLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTITVMVEN
Sbjct: 121  LSRTTNIQGINLLFSSRRGHLFLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTITVMVEN 180

Query: 181  SHGLRVRKKEVYMPSSIFQDDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPN 240
            SHGLRVRKKEVYMPSSIFQDDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPN
Sbjct: 181  SHGLRVRKKEVYMPSSIFQDDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPN 240

Query: 241  FEVKITPGKPYILTVPGHLDEMQLDIQARYIYGKPVQGVAYVRFGLLDEDGKKTFFRGLE 300
            FEVKITPGKPYILTVPGHLDEMQLDIQARYIYGKPVQGVAYVRFGLLDEDGKKTFFRGLE
Sbjct: 241  FEVKITPGKPYILTVPGHLDEMQLDIQARYIYGKPVQGVAYVRFGLLDEDGKKTFFRGLE 300

Query: 301  SQTKLVNGQSHISLSKAEFQDALEKLNMGITDLQGLRLYVAAAIIEYPGGEMEEAELTSW 360
            SQTKLVNGQSHISLSKAEFQDALEKLNMGITDLQGLRLYVAAAIIE PGGEMEEAELTSW
Sbjct: 301  SQTKLVNGQSHISLSKAEFQDALEKLNMGITDLQGLRLYVAAAIIESPGGEMEEAELTSW 360

Query: 361  YFVSSPFSLDLSKTKRHLVPGAPFLLQALVREMSGSPASGIPVKVSATVSSPGSVPEVQD 420
            YFVSSPFSLDLSKTKRHLVPGAPFLLQALVREMSGSPASGIPVKVSATVSSPGSVPEVQD
Sbjct: 361  YFVSSPFSLDLSKTKRHLVPGAPFLLQALVREMSGSPASGIPVKVSATVSSPGSVPEVQD 420

Query: 421  IQQNTDGSGQVSIPIIIPQTISELQLSVSAGSPHPAIARLTVAAPPSGGPGFLSIEWPDS 480
            IQQNTDGSGQVSIPIIIPQTISELQLSVSAGSPHPAIARLTVAAPPSGGPGFLSIE PDS
Sbjct: 421  IQQNTDGSGQVSIPIIIPQTISELQLSVSAGSPHPAIARLTVAAPPSGGPGFLSIERPDS 480

Query: 481  RPPRVGDTLNLNLRAVGSGATFSHYYYMILSRGQIVFMNREPKRTLTSVSVFVDHHLAPS 540
            RPPRVGDTLNLNLRAVGSGATFSHYYYMILSRGQIVFMNREPKRTLTSVSVFVDHHLAPS
Sbjct: 481  RPPRVGDTLNLNLRAVGSGATFSHYYYMILSRGQIVFMNREPKRTLTSVSVFVDHHLAPS 540

Query: 541  FYFVAFYYHGDHPVANSLRVDVQAGACEGKLELSVDGAKQYRNGESVKLHLETDSLALVA 600
            FYFVAFYYHGDHPVANSLRVDVQAGACEGKLELSVDGAKQYRNGESVKLHLETDSLALVA
Sbjct: 541  FYFVAFYYHGDHPVANSLRVDVQAGACEGKLELSVDGAKQYRNGESVKLHLETDSLALVA 600

Query: 601  LGALDTALYAAGSKSHKPLNMGKVFEAMNSYDLGCGPGGGDSALQVFQAAGLAFSDGDQW 660
            LGALDTALYAAGSKSHKPLNMGKVFEAMNSYDLGCGPGGGDSALQVFQAAGLAFSDGDQW
Sbjct: 601  LGALDTALYAAGSKSHKPLNMGKVFEAMNSYDLGCGPGGGDSALQVFQAAGLAFSDGDQW 660

Query: 661  TLSRKRLSCPKEKTTRKKRNVNFQKAINEKLGQYASPTAKRCCQDGVTRLPMMRSCEQRA 720
            TLSRKRLSCPKEKTTRKKRNVNFQKAINEKLGQYASPTAKRCCQDGVTRLPMMRSCEQRA
Sbjct: 661  TLSRKRLSCPKEKTTRKKRNVNFQKAINEKLGQYASPTAKRCCQDGVTRLPMMRSCEQRA 720

Query: 721  ARVQQPDCREPFLSCCQFAESLRKKSRDKGQAGLQRALEILQEEDLIDEDDIPVRSFFPE 780
            ARVQQPDCREPFLSCCQFAESLRKKSRDKGQAGLQRALEILQEEDLIDEDDIPVRSFFPE
Sbjct: 721  ARVQQPDCREPFLSCCQFAESLRKKSRDKGQAGLQRALEILQEEDLIDEDDIPVRSFFPE 780

Query: 781  NWLWRVETVDRFQILTLWLPDSLTTWEIHGLSLSKTKGLCVATPVQLRVFREFHLHLRLP 840
            NWLWRVETVDRFQILTLWLPDSLTTWEIHGLSLSKTKGLCVATPVQLRVFREFHLHLRLP
Sbjct: 781  NWLWRVETVDRFQILTLWLPDSLTTWEIHGLSLSKTKGLCVATPVQLRVFREFHLHLRLP 840

Query: 841  MSVRRFEQLELRPVLYNYLDKNLTVSVHVSPVEGLCLAGGGGLAQQVLVPAGSARPVAFS 900
            MSVRRFEQLELRPVLYNYLDKNLTVSVHVSPVEGLCLAGGGGLAQQVLVPAGSARPVAFS
Sbjct: 841  MSVRRFEQLELRPVLYNYLDKNLTVSVHVSPVEGLCLAGGGGLAQQVLVPAGSARPVAFS 900

Query: 901  VVPTAAAAVSLKVVARGSFEFPVGDAVSKVLQIEKEGAIHREELVYELNPLDHRGRTLEI 960
            VVPTAAAAVSLKVVARGSFEFPVGDAVSKVLQIEKEGAIHREELVYELNPLDHRGRTLEI
Sbjct: 901  VVPTAAAAVSLKVVARGSFEFPVGDAVSKVLQIEKEGAIHREELVYELNPLDHRGRTLEI 960

Query: 961  PGNSDPNMIPDGDFNSYVRVTASDPLDTLGSEGALSPGGVASLLRLPRGCGEQTMIYLAP 1020
            PGNSDPNMIPDGDFNSYVRVTASDPLDTLGSEGALSPGGVASLLRLPRGCGEQTMIYLAP
Sbjct: 961  PGNSDPNMIPDGDFNSYVRVTASDPLDTLGSEGALSPGGVASLLRLPRGCGEQTMIYLAP 1020

Query: 1021 TLAASRYLDKTEQWSTLPPETKDHAVDLIQKGYMRIQQFRKADGSYAAWLSRDSSTWLTA 1080
            TLAASRYLDKTEQWSTLPPETKDHAVDLIQKGYMRIQQFRKADGSYAAWLSRDSSTWLTA
Sbjct: 1021 TLAASRYLDKTEQWSTLPPETKDHAVDLIQKGYMRIQQFRKADGSYAAWLSRDSSTWLTA 1080

Query: 1081 FVLKVLSLAQEQVGGSPEKLQETSNWLLSQQQADGSFQDPCPVLDRSMQGGLVGNDETVA 1140
            FVLKVLSLAQEQVGGSPEKLQETSNWLLSQQQADGSFQDPCPVLDRSMQGGLVGNDETVA
Sbjct: 1081 FVLKVLSLAQEQVGGSPEKLQETSNWLLSQQQADGSFQDPCPVLDRSMQGGLVGNDETVA 1140

Query: 1141 LTAFVTIALHHGLAVFQDEGAEPLKQRVEASISKANSFLGEKASAGLLGAHAAAITAYAL 1200
            LTAFVTIALHHGLAVFQDEGAEPLKQRVEASISKANSFLGEKASAGLLGAHAAAITAYAL
Sbjct: 1141 LTAFVTIALHHGLAVFQDEGAEPLKQRVEASISKANSFLGEKASAGLLGAHAAAITAYAL 1200

Query: 1201 TLTKAPVDLLGVAHNNLMAMAQETGDNLYWGSVTGSQSNAVSPTPAPRNPSDPMPQAPAL 1260
            TLTKAPVDLLGVAHNNLMAMAQETGDNLYWGSVTGSQSNAVSPTPAPRNPSDPMPQAPAL
Sbjct: 1201 TLTKAPVDLLGVAHNNLMAMAQETGDNLYWGSVTGSQSNAVSPTPAPRNPSDPMPQAPAL 1260

Query: 1261 WIETTAYALLHLLLHEGKAEMADQAAAWLTRQGSFQGGFRSTQDTVIALDALSAYWIASH 1320
            WIETTAYALLHLLLHEGKAEMADQA+AWLTRQGSFQGGFRSTQDTVIALDALSAYWIASH
Sbjct: 1261 WIETTAYALLHLLLHEGKAEMADQASAWLTRQGSFQGGFRSTQDTVIALDALSAYWIASH 1320

Query: 1321 TTEERGLNVTLSSTGRNGFKSHALQLNNRQIRGLEEELQFSLGSKINVKVGGNSKGTLKV 1380
            TTEERGLNVTLSSTGRNGFKSHALQLNNRQIRGLEEELQFSLGSKINVKVGGNSKGTLKV
Sbjct: 1321 TTEERGLNVTLSSTGRNGFKSHALQLNNRQIRGLEEELQFSLGSKINVKVGGNSKGTLKV 1380

Query: 1381 LRTYNVLDMKNTTCQDLQIEVTVKGHVEYTMEANEDYEDYEYDELPAKDDPDAPLQPVTP 1440
            LRTYNVLDMKNTTCQDLQIEVTVKGHVEYTMEANEDYEDYEYDELPAKDDPDAPLQPVTP
Sbjct: 1381 LRTYNVLDMKNTTCQDLQIEVTVKGHVEYTMEANEDYEDYEYDELPAKDDPDAPLQPVTP 1440

Query: 1441 LQLFEGRRNRRRREAPKVVEEQESRVHYTVCIWRNGKVGLSGMAIADVTLLSGFHALRAD 1500
            LQLFEGRRNRRRREAPKVVEEQESRVHYTVCIWRNGKVGLSGMAIADVTLLSGFHALRAD
Sbjct: 1441 LQLFEGRRNRRRREAPKVVEEQESRVHYTVCIWRNGKVGLSGMAIADVTLLSGFHALRAD 1500

Query: 1501 LEKLTSLSDRYVSHFETEGPHVLLYFDSVPTSRECVGFEAVQEVPVGLVQPASATLYDYY 1560
            LEKLTSLSDRYVSHFETEGPHVLLYFDSVPTSRECVGFEAVQEVPVGLVQPASATLYDYY
Sbjct: 1501 LEKLTSLSDRYVSHFETEGPHVLLYFDSVPTSRECVGFEAVQEVPVGLVQPASATLYDYY 1560

Query: 1561 NPERRCSVFYGAPSKSRLLATLCSAEVCQCAEGKCPRQRRALERGLQDEDGYRMKFACYY 1620
            NPERRCSVFYGAPSKSRLLATLCSAEVCQCAEGKCPRQRRALERGLQDEDGYRMKFACYY
Sbjct: 1561 NPERRCSVFYGAPSKSRLLATLCSAEVCQCAEGKCPRQRRALERGLQDEDGYRMKFACYY 1620

Query: 1621 PRVEYGFQVKVLREDSRAAFRLFETKITQVLHFTKDVKAAANQMRNFLVRASCRLRLEPG 1680
            PRVEYGFQVKVLREDSRAAFRLFETKITQVLHFTKDVKAAANQMRNFLVRASCRLRLEPG
Sbjct: 1621 PRVEYGFQVKVLREDSRAAFRLFETKITQVLHFTKDVKAAANQMRNFLVRASCRLRLEPG 1680

Query: 1681 KEYLIMGLDGATYDLEGHPQYLLDSNSWIEEMPSERLCRSTRQRAACAQLNDFLQEYGTQ 1740
            KEYLIMGLDGATYDLEGHPQYLLDSNSWIEEMPSERLCRSTRQRAACAQLNDFLQEYGTQ
Sbjct: 1681 KEYLIMGLDGATYDLEGHPQYLLDSNSWIEEMPSERLCRSTRQRAACAQLNDFLQEYGTQ 1740

Query: 1741 GCQV 1744
            GCQV
Sbjct: 1741 GCQV 1744


>gi|178557739 complement component 4B preproprotein [Homo sapiens]
          Length = 1744

 Score = 3457 bits (8963), Expect = 0.0
 Identities = 1733/1744 (99%), Positives = 1735/1744 (99%)

Query: 1    MRLLWGLIWASSFFTLSLQKPRLLLFSPSVVHLGVPLSVGVQLQDVPRGQVVKGSVFLRN 60
            MRLLWGLIWASSFFTLSLQKPRLLLFSPSVVHLGVPLSVGVQLQDVPRGQVVKGSVFLRN
Sbjct: 1    MRLLWGLIWASSFFTLSLQKPRLLLFSPSVVHLGVPLSVGVQLQDVPRGQVVKGSVFLRN 60

Query: 61   PSRNNVPCSPKVDFTLSSERDFALLSLQVPLKDAKSCGLHQLLRGPEVQLVAHSPWLKDS 120
            PSRNNVPCSPKVDFTLSSERDFALLSLQVPLKDAKSCGLHQLLRGPEVQLVAHSPWLKDS
Sbjct: 61   PSRNNVPCSPKVDFTLSSERDFALLSLQVPLKDAKSCGLHQLLRGPEVQLVAHSPWLKDS 120

Query: 121  LSRTTNIQGINLLFSSRRGHLFLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTITVMVEN 180
            LSRTTNIQGINLLFSSRRGHLFLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTITVMVEN
Sbjct: 121  LSRTTNIQGINLLFSSRRGHLFLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTITVMVEN 180

Query: 181  SHGLRVRKKEVYMPSSIFQDDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPN 240
            SHGLRVRKKEVYMPSSIFQDDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPN
Sbjct: 181  SHGLRVRKKEVYMPSSIFQDDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPN 240

Query: 241  FEVKITPGKPYILTVPGHLDEMQLDIQARYIYGKPVQGVAYVRFGLLDEDGKKTFFRGLE 300
            FEVKITPGKPYILTVPGHLDEMQLDIQARYIYGKPVQGVAYVRFGLLDEDGKKTFFRGLE
Sbjct: 241  FEVKITPGKPYILTVPGHLDEMQLDIQARYIYGKPVQGVAYVRFGLLDEDGKKTFFRGLE 300

Query: 301  SQTKLVNGQSHISLSKAEFQDALEKLNMGITDLQGLRLYVAAAIIEYPGGEMEEAELTSW 360
            SQTKLVNGQSHISLSKAEFQDALEKLNMGITDLQGLRLYVAAAIIE PGGEMEEAELTSW
Sbjct: 301  SQTKLVNGQSHISLSKAEFQDALEKLNMGITDLQGLRLYVAAAIIESPGGEMEEAELTSW 360

Query: 361  YFVSSPFSLDLSKTKRHLVPGAPFLLQALVREMSGSPASGIPVKVSATVSSPGSVPEVQD 420
            YFVSSPFSLDLSKTKRHLVPGAPFLLQALVREMSGSPASGIPVKVSATVSSPGSVPEVQD
Sbjct: 361  YFVSSPFSLDLSKTKRHLVPGAPFLLQALVREMSGSPASGIPVKVSATVSSPGSVPEVQD 420

Query: 421  IQQNTDGSGQVSIPIIIPQTISELQLSVSAGSPHPAIARLTVAAPPSGGPGFLSIEWPDS 480
            IQQNTDGSGQVSIPIIIPQTISELQLSVSAGSPHPAIARLTVAAPPSGGPGFLSIE PDS
Sbjct: 421  IQQNTDGSGQVSIPIIIPQTISELQLSVSAGSPHPAIARLTVAAPPSGGPGFLSIERPDS 480

Query: 481  RPPRVGDTLNLNLRAVGSGATFSHYYYMILSRGQIVFMNREPKRTLTSVSVFVDHHLAPS 540
            RPPRVGDTLNLNLRAVGSGATFSHYYYMILSRGQIVFMNREPKRTLTSVSVFVDHHLAPS
Sbjct: 481  RPPRVGDTLNLNLRAVGSGATFSHYYYMILSRGQIVFMNREPKRTLTSVSVFVDHHLAPS 540

Query: 541  FYFVAFYYHGDHPVANSLRVDVQAGACEGKLELSVDGAKQYRNGESVKLHLETDSLALVA 600
            FYFVAFYYHGDHPVANSLRVDVQAGACEGKLELSVDGAKQYRNGESVKLHLETDSLALVA
Sbjct: 541  FYFVAFYYHGDHPVANSLRVDVQAGACEGKLELSVDGAKQYRNGESVKLHLETDSLALVA 600

Query: 601  LGALDTALYAAGSKSHKPLNMGKVFEAMNSYDLGCGPGGGDSALQVFQAAGLAFSDGDQW 660
            LGALDTALYAAGSKSHKPLNMGKVFEAMNSYDLGCGPGGGDSALQVFQAAGLAFSDGDQW
Sbjct: 601  LGALDTALYAAGSKSHKPLNMGKVFEAMNSYDLGCGPGGGDSALQVFQAAGLAFSDGDQW 660

Query: 661  TLSRKRLSCPKEKTTRKKRNVNFQKAINEKLGQYASPTAKRCCQDGVTRLPMMRSCEQRA 720
            TLSRKRLSCPKEKTTRKKRNVNFQKAINEKLGQYASPTAKRCCQDGVTRLPMMRSCEQRA
Sbjct: 661  TLSRKRLSCPKEKTTRKKRNVNFQKAINEKLGQYASPTAKRCCQDGVTRLPMMRSCEQRA 720

Query: 721  ARVQQPDCREPFLSCCQFAESLRKKSRDKGQAGLQRALEILQEEDLIDEDDIPVRSFFPE 780
            ARVQQPDCREPFLSCCQFAESLRKKSRDKGQAGLQRALEILQEEDLIDEDDIPVRSFFPE
Sbjct: 721  ARVQQPDCREPFLSCCQFAESLRKKSRDKGQAGLQRALEILQEEDLIDEDDIPVRSFFPE 780

Query: 781  NWLWRVETVDRFQILTLWLPDSLTTWEIHGLSLSKTKGLCVATPVQLRVFREFHLHLRLP 840
            NWLWRVETVDRFQILTLWLPDSLTTWEIHGLSLSKTKGLCVATPVQLRVFREFHLHLRLP
Sbjct: 781  NWLWRVETVDRFQILTLWLPDSLTTWEIHGLSLSKTKGLCVATPVQLRVFREFHLHLRLP 840

Query: 841  MSVRRFEQLELRPVLYNYLDKNLTVSVHVSPVEGLCLAGGGGLAQQVLVPAGSARPVAFS 900
            MSVRRFEQLELRPVLYNYLDKNLTVSVHVSPVEGLCLAGGGGLAQQVLVPAGSARPVAFS
Sbjct: 841  MSVRRFEQLELRPVLYNYLDKNLTVSVHVSPVEGLCLAGGGGLAQQVLVPAGSARPVAFS 900

Query: 901  VVPTAAAAVSLKVVARGSFEFPVGDAVSKVLQIEKEGAIHREELVYELNPLDHRGRTLEI 960
            VVPTAA AVSLKVVARGSFEFPVGDAVSKVLQIEKEGAIHREELVYELNPLDHRGRTLEI
Sbjct: 901  VVPTAATAVSLKVVARGSFEFPVGDAVSKVLQIEKEGAIHREELVYELNPLDHRGRTLEI 960

Query: 961  PGNSDPNMIPDGDFNSYVRVTASDPLDTLGSEGALSPGGVASLLRLPRGCGEQTMIYLAP 1020
            PGNSDPNMIPDGDFNSYVRVTASDPLDTLGSEGALSPGGVASLLRLPRGCGEQTMIYLAP
Sbjct: 961  PGNSDPNMIPDGDFNSYVRVTASDPLDTLGSEGALSPGGVASLLRLPRGCGEQTMIYLAP 1020

Query: 1021 TLAASRYLDKTEQWSTLPPETKDHAVDLIQKGYMRIQQFRKADGSYAAWLSRDSSTWLTA 1080
            TLAASRYLDKTEQWSTLPPETKDHAVDLIQKGYMRIQQFRKADGSYAAWLSR SSTWLTA
Sbjct: 1021 TLAASRYLDKTEQWSTLPPETKDHAVDLIQKGYMRIQQFRKADGSYAAWLSRGSSTWLTA 1080

Query: 1081 FVLKVLSLAQEQVGGSPEKLQETSNWLLSQQQADGSFQDPCPVLDRSMQGGLVGNDETVA 1140
            FVLKVLSLAQEQVGGSPEKLQETSNWLLSQQQADGSFQD  PV+ RSMQGGLVGNDETVA
Sbjct: 1081 FVLKVLSLAQEQVGGSPEKLQETSNWLLSQQQADGSFQDLSPVIHRSMQGGLVGNDETVA 1140

Query: 1141 LTAFVTIALHHGLAVFQDEGAEPLKQRVEASISKANSFLGEKASAGLLGAHAAAITAYAL 1200
            LTAFVTIALHHGLAVFQDEGAEPLKQRVEASISKA+SFLGEKASAGLLGAHAAAITAYAL
Sbjct: 1141 LTAFVTIALHHGLAVFQDEGAEPLKQRVEASISKASSFLGEKASAGLLGAHAAAITAYAL 1200

Query: 1201 TLTKAPVDLLGVAHNNLMAMAQETGDNLYWGSVTGSQSNAVSPTPAPRNPSDPMPQAPAL 1260
            TLTKAP DL GVAHNNLMAMAQETGDNLYWGSVTGSQSNAVSPTPAPRNPSDPMPQAPAL
Sbjct: 1201 TLTKAPADLRGVAHNNLMAMAQETGDNLYWGSVTGSQSNAVSPTPAPRNPSDPMPQAPAL 1260

Query: 1261 WIETTAYALLHLLLHEGKAEMADQAAAWLTRQGSFQGGFRSTQDTVIALDALSAYWIASH 1320
            WIETTAYALLHLLLHEGKAEMADQAAAWLTRQGSFQGGFRSTQDTVIALDALSAYWIASH
Sbjct: 1261 WIETTAYALLHLLLHEGKAEMADQAAAWLTRQGSFQGGFRSTQDTVIALDALSAYWIASH 1320

Query: 1321 TTEERGLNVTLSSTGRNGFKSHALQLNNRQIRGLEEELQFSLGSKINVKVGGNSKGTLKV 1380
            TTEERGLNVTLSSTGRNGFKSHALQLNNRQIRGLEEELQFSLGSKINVKVGGNSKGTLKV
Sbjct: 1321 TTEERGLNVTLSSTGRNGFKSHALQLNNRQIRGLEEELQFSLGSKINVKVGGNSKGTLKV 1380

Query: 1381 LRTYNVLDMKNTTCQDLQIEVTVKGHVEYTMEANEDYEDYEYDELPAKDDPDAPLQPVTP 1440
            LRTYNVLDMKNTTCQDLQIEVTVKGHVEYTMEANEDYEDYEYDELPAKDDPDAPLQPVTP
Sbjct: 1381 LRTYNVLDMKNTTCQDLQIEVTVKGHVEYTMEANEDYEDYEYDELPAKDDPDAPLQPVTP 1440

Query: 1441 LQLFEGRRNRRRREAPKVVEEQESRVHYTVCIWRNGKVGLSGMAIADVTLLSGFHALRAD 1500
            LQLFEGRRNRRRREAPKVVEEQESRVHYTVCIWRNGKVGLSGMAIADVTLLSGFHALRAD
Sbjct: 1441 LQLFEGRRNRRRREAPKVVEEQESRVHYTVCIWRNGKVGLSGMAIADVTLLSGFHALRAD 1500

Query: 1501 LEKLTSLSDRYVSHFETEGPHVLLYFDSVPTSRECVGFEAVQEVPVGLVQPASATLYDYY 1560
            LEKLTSLSDRYVSHFETEGPHVLLYFDSVPTSRECVGFEAVQEVPVGLVQPASATLYDYY
Sbjct: 1501 LEKLTSLSDRYVSHFETEGPHVLLYFDSVPTSRECVGFEAVQEVPVGLVQPASATLYDYY 1560

Query: 1561 NPERRCSVFYGAPSKSRLLATLCSAEVCQCAEGKCPRQRRALERGLQDEDGYRMKFACYY 1620
            NPERRCSVFYGAPSKSRLLATLCSAEVCQCAEGKCPRQRRALERGLQDEDGYRMKFACYY
Sbjct: 1561 NPERRCSVFYGAPSKSRLLATLCSAEVCQCAEGKCPRQRRALERGLQDEDGYRMKFACYY 1620

Query: 1621 PRVEYGFQVKVLREDSRAAFRLFETKITQVLHFTKDVKAAANQMRNFLVRASCRLRLEPG 1680
            PRVEYGFQVKVLREDSRAAFRLFETKITQVLHFTKDVKAAANQMRNFLVRASCRLRLEPG
Sbjct: 1621 PRVEYGFQVKVLREDSRAAFRLFETKITQVLHFTKDVKAAANQMRNFLVRASCRLRLEPG 1680

Query: 1681 KEYLIMGLDGATYDLEGHPQYLLDSNSWIEEMPSERLCRSTRQRAACAQLNDFLQEYGTQ 1740
            KEYLIMGLDGATYDLEGHPQYLLDSNSWIEEMPSERLCRSTRQRAACAQLNDFLQEYGTQ
Sbjct: 1681 KEYLIMGLDGATYDLEGHPQYLLDSNSWIEEMPSERLCRSTRQRAACAQLNDFLQEYGTQ 1740

Query: 1741 GCQV 1744
            GCQV
Sbjct: 1741 GCQV 1744


>gi|239740686 PREDICTED: similar to C4A protein isoform 2 [Homo
            sapiens]
          Length = 1698

 Score = 3374 bits (8748), Expect = 0.0
 Identities = 1698/1744 (97%), Positives = 1698/1744 (97%), Gaps = 46/1744 (2%)

Query: 1    MRLLWGLIWASSFFTLSLQKPRLLLFSPSVVHLGVPLSVGVQLQDVPRGQVVKGSVFLRN 60
            MRLLWGLIWASSFFTLSLQKPRLLLFSPSVVHLGVPLSVGVQLQDVPRGQVVKGSVFLRN
Sbjct: 1    MRLLWGLIWASSFFTLSLQKPRLLLFSPSVVHLGVPLSVGVQLQDVPRGQVVKGSVFLRN 60

Query: 61   PSRNNVPCSPKVDFTLSSERDFALLSLQVPLKDAKSCGLHQLLRGPEVQLVAHSPWLKDS 120
            PSRNNVPCSPKVDFTLSSERDFALLSLQVPLKDAKSCGLHQLLRGPEVQLVAHSPWLKDS
Sbjct: 61   PSRNNVPCSPKVDFTLSSERDFALLSLQVPLKDAKSCGLHQLLRGPEVQLVAHSPWLKDS 120

Query: 121  LSRTTNIQGINLLFSSRRGHLFLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTITVMVEN 180
            LSRTTNIQGINLLFSSRRGHLFLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTITVMVEN
Sbjct: 121  LSRTTNIQGINLLFSSRRGHLFLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTITVMVEN 180

Query: 181  SHGLRVRKKEVYMPSSIFQDDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPN 240
            SHGLRVRKKEVYMPSSIFQDDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPN
Sbjct: 181  SHGLRVRKKEVYMPSSIFQDDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPN 240

Query: 241  FEVKITPGKPYILTVPGHLDEMQLDIQARYIYGKPVQGVAYVRFGLLDEDGKKTFFRGLE 300
            FEVKITPGKPYILTVPGHLDEMQLDIQARYIYGKPVQGVAYVRFGLLDEDGKKTFFRGLE
Sbjct: 241  FEVKITPGKPYILTVPGHLDEMQLDIQARYIYGKPVQGVAYVRFGLLDEDGKKTFFRGLE 300

Query: 301  SQTKLVNGQSHISLSKAEFQDALEKLNMGITDLQGLRLYVAAAIIEYPGGEMEEAELTSW 360
            SQTKLVNGQSHISLSKAEFQDALEKLNMGITDLQGLRLYVAAAIIEYPGGEMEEAELTSW
Sbjct: 301  SQTKLVNGQSHISLSKAEFQDALEKLNMGITDLQGLRLYVAAAIIEYPGGEMEEAELTSW 360

Query: 361  YFVSSPFSLDLSKTKRHLVPGAPFLLQALVREMSGSPASGIPVKVSATVSSPGSVPEVQD 420
            YFVSSPFSLDLSKTKRHLVPGAPFLLQALVREMSGSPASGIPVKVSATVSSPGSVPEVQD
Sbjct: 361  YFVSSPFSLDLSKTKRHLVPGAPFLLQALVREMSGSPASGIPVKVSATVSSPGSVPEVQD 420

Query: 421  IQQNTDGSGQVSIPIIIPQTISELQLSVSAGSPHPAIARLTVAAPPSGGPGFLSIEWPDS 480
            IQQNTDGSGQVSIPIIIPQTISELQLSVSAGSPHPAIARLTVAAPPSGGPGFLSIEWPDS
Sbjct: 421  IQQNTDGSGQVSIPIIIPQTISELQLSVSAGSPHPAIARLTVAAPPSGGPGFLSIEWPDS 480

Query: 481  RPPRVGDTLNLNLRAVGSGATFSHYYYMILSRGQIVFMNREPKRTLTSVSVFVDHHLAPS 540
            RPPRVGDTLNLNLRAVGSGATFSHYYYMILSRGQIVFMNREPKRTLTSVSVFVDHHLAPS
Sbjct: 481  RPPRVGDTLNLNLRAVGSGATFSHYYYMILSRGQIVFMNREPKRTLTSVSVFVDHHLAPS 540

Query: 541  FYFVAFYYHGDHPVANSLRVDVQAGACEGKLELSVDGAKQYRNGESVKLHLETDSLALVA 600
            FYFVAFYYHGDHPVANSLRVDVQAGACEGKLELSVDGAKQYRNGESVKLHLETDSLALVA
Sbjct: 541  FYFVAFYYHGDHPVANSLRVDVQAGACEGKLELSVDGAKQYRNGESVKLHLETDSLALVA 600

Query: 601  LGALDTALYAAGSKSHKPLNMGKVFEAMNSYDLGCGPGGGDSALQVFQAAGLAFSDGDQW 660
            LGALDTALYAAGSKSHKPLNMGKVFEAMNSYDLGCGPGGGDSALQVFQAAGLAFSDGDQW
Sbjct: 601  LGALDTALYAAGSKSHKPLNMGKVFEAMNSYDLGCGPGGGDSALQVFQAAGLAFSDGDQW 660

Query: 661  TLSRKRLSCPKEKTTRKKRNVNFQKAINEKLGQYASPTAKRCCQDGVTRLPMMRSCEQRA 720
            TLSRKRLSCPKEKTTRKKRNVNFQKAINEKLGQYASPTAKRCCQDGVTRLPMMRSCEQRA
Sbjct: 661  TLSRKRLSCPKEKTTRKKRNVNFQKAINEKLGQYASPTAKRCCQDGVTRLPMMRSCEQRA 720

Query: 721  ARVQQPDCREPFLSCCQFAESLRKKSRDKGQAGLQRALEILQEEDLIDEDDIPVRSFFPE 780
            ARVQQPDCREPFLSCCQFAESLRKKSRDKGQAGLQRALEILQEEDLIDEDDIPVRSFFPE
Sbjct: 721  ARVQQPDCREPFLSCCQFAESLRKKSRDKGQAGLQRALEILQEEDLIDEDDIPVRSFFPE 780

Query: 781  NWLWRVETVDRFQILTLWLPDSLTTWEIHGLSLSKTKGLCVATPVQLRVFREFHLHLRLP 840
            NWLWRVETVDRFQILTLWLPDSLTTWEIHGLSLSKTKGLCVATPVQLRVFREFHLHLRLP
Sbjct: 781  NWLWRVETVDRFQILTLWLPDSLTTWEIHGLSLSKTKGLCVATPVQLRVFREFHLHLRLP 840

Query: 841  MSVRRFEQLELRPVLYNYLDKNLTVSVHVSPVEGLCLAGGGGLAQQVLVPAGSARPVAFS 900
            MSVRRFEQLELRPVLYNYLDKNLTVSVHVSPVEGLCLAGGGGLAQQVLVPAGSARPVAFS
Sbjct: 841  MSVRRFEQLELRPVLYNYLDKNLTVSVHVSPVEGLCLAGGGGLAQQVLVPAGSARPVAFS 900

Query: 901  VVPTAAAAVSLKVVARGSFEFPVGDAVSKVLQIEKEGAIHREELVYELNPLDHRGRTLEI 960
            VVPTAAAAVSLKVVARGSFEFPVGDAVSKVLQIEKEGAIHREELVYELNPLDHRGRTLEI
Sbjct: 901  VVPTAAAAVSLKVVARGSFEFPVGDAVSKVLQIEKEGAIHREELVYELNPLDHRGRTLEI 960

Query: 961  PGNSDPNMIPDGDFNSYVRVTASDPLDTLGSEGALSPGGVASLLRLPRGCGEQTMIYLAP 1020
            PGNSDPNMIPDGDFNSYVRVTASDPLDTLGSEGALSPGGVASLLRLPRGCGEQTMIYLAP
Sbjct: 961  PGNSDPNMIPDGDFNSYVRVTASDPLDTLGSEGALSPGGVASLLRLPRGCGEQTMIYLAP 1020

Query: 1021 TLAASRYLDKTEQWSTLPPETKDHAVDLIQKGYMRIQQFRKADGSYAAWLSRDSSTWLTA 1080
            TLAASRYLDKTEQWSTLPPETKDHAVDLIQKGYMRIQQFRKADGSYAAWLSRDSSTWLTA
Sbjct: 1021 TLAASRYLDKTEQWSTLPPETKDHAVDLIQKGYMRIQQFRKADGSYAAWLSRDSSTWLTA 1080

Query: 1081 FVLKVLSLAQEQVGGSPEKLQETSNWLLSQQQADGSFQDPCPVLDRSMQGGLVGNDETVA 1140
            FVLKVLSLAQEQVGGSPEKLQETSNWLLSQQQADGSFQDPCPVLDRSMQGGLVGNDETVA
Sbjct: 1081 FVLKVLSLAQEQVGGSPEKLQETSNWLLSQQQADGSFQDPCPVLDRSMQGGLVGNDETVA 1140

Query: 1141 LTAFVTIALHHGLAVFQDEGAEPLKQRVEASISKANSFLGEKASAGLLGAHAAAITAYAL 1200
            LTAFVTIALHHGLAVFQDEGAEPLKQRVEASISKANSFLGEKASAGLLGAHAAAITAYAL
Sbjct: 1141 LTAFVTIALHHGLAVFQDEGAEPLKQRVEASISKANSFLGEKASAGLLGAHAAAITAYAL 1200

Query: 1201 TLTKAPVDLLGVAHNNLMAMAQETGDNLYWGSVTGSQSNAVSPTPAPRNPSDPMPQAPAL 1260
            TLTKAPVDLLGVAHNNLMAMAQETGDNLYWGSVTGSQSNAVSPTPAPRNPSDPMPQAPAL
Sbjct: 1201 TLTKAPVDLLGVAHNNLMAMAQETGDNLYWGSVTGSQSNAVSPTPAPRNPSDPMPQAPAL 1260

Query: 1261 WIETTAYALLHLLLHEGKAEMADQAAAWLTRQGSFQGGFRSTQDTVIALDALSAYWIASH 1320
            WIETTAYALLHLLLHEGKAEMADQAAAWLTRQGSFQGGFRSTQDTVIALDALSAYWIASH
Sbjct: 1261 WIETTAYALLHLLLHEGKAEMADQAAAWLTRQGSFQGGFRSTQDTVIALDALSAYWIASH 1320

Query: 1321 TTEERGLNVTLSSTGRNGFKSHALQLNNRQIRGLEEELQFSLGSKINVKVGGNSKGTLKV 1380
            TTEERGLNVTLSSTGRNGFKSHALQLNNRQIRGLEEELQFSLGSKINVKVGGNSKGTLKV
Sbjct: 1321 TTEERGLNVTLSSTGRNGFKSHALQLNNRQIRGLEEELQFSLGSKINVKVGGNSKGTLKV 1380

Query: 1381 LRTYNVLDMKNTTCQDLQIEVTVKGHVEYTMEANEDYEDYEYDELPAKDDPDAPLQPVTP 1440
            LRTYNVLDMKNTTCQDLQIEVTVKGHVEYTMEANEDYEDYEYDELPAKDDPDAPLQPVTP
Sbjct: 1381 LRTYNVLDMKNTTCQDLQIEVTVKGHVEYTMEANEDYEDYEYDELPAKDDPDAPLQPVTP 1440

Query: 1441 LQLFEGRRNRRRREAPKVVEEQESRVHYTVCIWRNGKVGLSGMAIADVTLLSGFHALRAD 1500
            LQLFEGRRNRRRREAP                                            
Sbjct: 1441 LQLFEGRRNRRRREAP-------------------------------------------- 1456

Query: 1501 LEKLTSLSDRYVSHFETEGPHVLLYFDSVPTSRECVGFEAVQEVPVGLVQPASATLYDYY 1560
              KLTSLSDRYVSHFETEGPHVLLYFDSVPTSRECVGFEAVQEVPVGLVQPASATLYDYY
Sbjct: 1457 --KLTSLSDRYVSHFETEGPHVLLYFDSVPTSRECVGFEAVQEVPVGLVQPASATLYDYY 1514

Query: 1561 NPERRCSVFYGAPSKSRLLATLCSAEVCQCAEGKCPRQRRALERGLQDEDGYRMKFACYY 1620
            NPERRCSVFYGAPSKSRLLATLCSAEVCQCAEGKCPRQRRALERGLQDEDGYRMKFACYY
Sbjct: 1515 NPERRCSVFYGAPSKSRLLATLCSAEVCQCAEGKCPRQRRALERGLQDEDGYRMKFACYY 1574

Query: 1621 PRVEYGFQVKVLREDSRAAFRLFETKITQVLHFTKDVKAAANQMRNFLVRASCRLRLEPG 1680
            PRVEYGFQVKVLREDSRAAFRLFETKITQVLHFTKDVKAAANQMRNFLVRASCRLRLEPG
Sbjct: 1575 PRVEYGFQVKVLREDSRAAFRLFETKITQVLHFTKDVKAAANQMRNFLVRASCRLRLEPG 1634

Query: 1681 KEYLIMGLDGATYDLEGHPQYLLDSNSWIEEMPSERLCRSTRQRAACAQLNDFLQEYGTQ 1740
            KEYLIMGLDGATYDLEGHPQYLLDSNSWIEEMPSERLCRSTRQRAACAQLNDFLQEYGTQ
Sbjct: 1635 KEYLIMGLDGATYDLEGHPQYLLDSNSWIEEMPSERLCRSTRQRAACAQLNDFLQEYGTQ 1694

Query: 1741 GCQV 1744
            GCQV
Sbjct: 1695 GCQV 1698


>gi|239758130 PREDICTED: similar to complement component 4B (Childo
            blood group), partial [Homo sapiens]
          Length = 666

 Score = 1318 bits (3412), Expect = 0.0
 Identities = 659/666 (98%), Positives = 660/666 (99%)

Query: 1079 TAFVLKVLSLAQEQVGGSPEKLQETSNWLLSQQQADGSFQDPCPVLDRSMQGGLVGNDET 1138
            TAFVLKVLSLAQEQVGGS EKLQETSNWLLSQQQADGSFQD  PV+ RSMQGGLVGNDET
Sbjct: 1    TAFVLKVLSLAQEQVGGSREKLQETSNWLLSQQQADGSFQDLSPVIHRSMQGGLVGNDET 60

Query: 1139 VALTAFVTIALHHGLAVFQDEGAEPLKQRVEASISKANSFLGEKASAGLLGAHAAAITAY 1198
            VALTAFVTIALHHGLAVFQDEGAEPLKQRVEASISKANSFLGEKASAGLLGAHAAAITAY
Sbjct: 61   VALTAFVTIALHHGLAVFQDEGAEPLKQRVEASISKANSFLGEKASAGLLGAHAAAITAY 120

Query: 1199 ALTLTKAPVDLLGVAHNNLMAMAQETGDNLYWGSVTGSQSNAVSPTPAPRNPSDPMPQAP 1258
            ALTLTKAP DL GVAHNNLMAMAQETGDNLYWGSVTGSQSNAVSPTPAPRNPSDPMPQAP
Sbjct: 121  ALTLTKAPADLRGVAHNNLMAMAQETGDNLYWGSVTGSQSNAVSPTPAPRNPSDPMPQAP 180

Query: 1259 ALWIETTAYALLHLLLHEGKAEMADQAAAWLTRQGSFQGGFRSTQDTVIALDALSAYWIA 1318
            ALWIETTAYALLHLLLHEGKAEMADQAAAWLTRQGSFQGGFRSTQDTVIALDALSAYWIA
Sbjct: 181  ALWIETTAYALLHLLLHEGKAEMADQAAAWLTRQGSFQGGFRSTQDTVIALDALSAYWIA 240

Query: 1319 SHTTEERGLNVTLSSTGRNGFKSHALQLNNRQIRGLEEELQFSLGSKINVKVGGNSKGTL 1378
            SHTTEERGLNVTLSSTGRNGFKSHALQLNNRQIRGLEEELQFSLGSKINVKVGGNSKGTL
Sbjct: 241  SHTTEERGLNVTLSSTGRNGFKSHALQLNNRQIRGLEEELQFSLGSKINVKVGGNSKGTL 300

Query: 1379 KVLRTYNVLDMKNTTCQDLQIEVTVKGHVEYTMEANEDYEDYEYDELPAKDDPDAPLQPV 1438
            KVLRTYNVLDMKNTTCQDLQIEVTVKGHVEYTMEANEDYEDYEYDELPAKDDPDAPLQPV
Sbjct: 301  KVLRTYNVLDMKNTTCQDLQIEVTVKGHVEYTMEANEDYEDYEYDELPAKDDPDAPLQPV 360

Query: 1439 TPLQLFEGRRNRRRREAPKVVEEQESRVHYTVCIWRNGKVGLSGMAIADVTLLSGFHALR 1498
            TPLQLFEGRRNRRRREAPKVVEEQESRVHYTVCIWRNGKVGLSGMAIADVTLLSGFHALR
Sbjct: 361  TPLQLFEGRRNRRRREAPKVVEEQESRVHYTVCIWRNGKVGLSGMAIADVTLLSGFHALR 420

Query: 1499 ADLEKLTSLSDRYVSHFETEGPHVLLYFDSVPTSRECVGFEAVQEVPVGLVQPASATLYD 1558
            ADLEKLTSLSDRYVSHFETEGPHVLLYFDSVPTSRECVGFEAVQEVPVGLVQPASATLYD
Sbjct: 421  ADLEKLTSLSDRYVSHFETEGPHVLLYFDSVPTSRECVGFEAVQEVPVGLVQPASATLYD 480

Query: 1559 YYNPERRCSVFYGAPSKSRLLATLCSAEVCQCAEGKCPRQRRALERGLQDEDGYRMKFAC 1618
            YYNPERRCSVFYGAPSKSRLLATLCSAEVCQCAEGKCPRQRRALERGLQDEDGYRMKFAC
Sbjct: 481  YYNPERRCSVFYGAPSKSRLLATLCSAEVCQCAEGKCPRQRRALERGLQDEDGYRMKFAC 540

Query: 1619 YYPRVEYGFQVKVLREDSRAAFRLFETKITQVLHFTKDVKAAANQMRNFLVRASCRLRLE 1678
            YYPRVEYGFQVKVLREDSRAAFRLFETKITQVLHFTKDVKAAANQMRNFLVRASCRLRLE
Sbjct: 541  YYPRVEYGFQVKVLREDSRAAFRLFETKITQVLHFTKDVKAAANQMRNFLVRASCRLRLE 600

Query: 1679 PGKEYLIMGLDGATYDLEGHPQYLLDSNSWIEEMPSERLCRSTRQRAACAQLNDFLQEYG 1738
            PGKEYLIMGLDGATYDLEGHPQYLLDSNSWIEEMPSERLCRSTRQRAACAQLNDFLQEYG
Sbjct: 601  PGKEYLIMGLDGATYDLEGHPQYLLDSNSWIEEMPSERLCRSTRQRAACAQLNDFLQEYG 660

Query: 1739 TQGCQV 1744
            TQGCQV
Sbjct: 661  TQGCQV 666


>gi|115298678 complement component 3 precursor [Homo sapiens]
          Length = 1663

 Score =  636 bits (1640), Expect = 0.0
 Identities = 502/1657 (30%), Positives = 791/1657 (47%), Gaps = 162/1657 (9%)

Query: 132  LLFSSRRGHLFLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTITVMVENSHGLRVRKKEV 191
            +L S + G+LF+QTD+ IY PG  V YR+F ++ K+ P   T+ V +EN  G+ V++  +
Sbjct: 121  VLVSLQSGYLFIQTDKTIYTPGSTVLYRIFTVNHKLLPVGRTVMVNIENPEGIPVKQDSL 180

Query: 192  YMPSS--IFQDDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKITPGK 249
               +   +    + IP++   G WKI A + +  +   ST+FEVK+YVLP+FEV + P +
Sbjct: 181  SSQNQLGVLPLSWDIPELVNMGQWKIRAYYENSPQQVFSTEFEVKEYVLPSFEVIVEPTE 240

Query: 250  P--YILTVPGHLDEMQLDIQARYIYGKPVQGVAYVRFGLLDEDGKKTFFRGLESQTKLVN 307
               YI    G    +++ I AR++YGK V+G A+V FG+ D + + +    L+ +  + +
Sbjct: 241  KFYYIYNEKG----LEVTITARFLYGKKVEGTAFVIFGIQDGEQRISLPESLK-RIPIED 295

Query: 308  GQSHISLSKAEFQDALEKLNMGITDLQGLRLYVAAAIIEYPGGEMEEAELTSWYFVSSPF 367
            G   + LS+    D ++  N    DL G  LYV+A +I + G +M +AE +    V+SP+
Sbjct: 296  GSGEVVLSRKVLLDGVQ--NPRAEDLVGKSLYVSATVILHSGSDMVQAERSGIPIVTSPY 353

Query: 368  SLDLSKTKRHLVPGAPFLLQALVREMSGSPASGIPVKVSA--TVSSPGSVPEVQDIQQNT 425
             +  +KT ++  PG PF L   V    GSPA  +PV V    TV S      V  +  NT
Sbjct: 354  QIHFTKTPKYFKPGMPFDLMVFVTNPDGSPAYRVPVAVQGEDTVQSLTQGDGVAKLSINT 413

Query: 426  DGSGQVSIPIIIPQTISELQLSVSAGSPHPAIARLTVAAPPSGGPGFLSIEWPDSRPPRV 485
              S Q  + I +     EL  +  A     A+   TV    S     LS+   + RP   
Sbjct: 414  HPS-QKPLSITVRTKKQELSEAEQATRTMQALPYSTVGN--SNNYLHLSVLRTELRP--- 467

Query: 486  GDTLNLNLRAV---GSGATFSHYYYMILSRGQIVFMNR---EPKRTLTSVSVFVDHHLAP 539
            G+TLN+N          A   +Y Y+I+++G+++   R   EP + L  + + +     P
Sbjct: 468  GETLNVNFLLRMDRAHEAKIRYYTYLIMNKGRLLKAGRQVREPGQDLVVLPLSITTDFIP 527

Query: 540  SFYFVAFYY----HGDHPV-ANSLRVDVQAGACEGKLELSVDGAKQYRN---GESVKLHL 591
            SF  VA+Y      G   V A+S+ VDV+  +C G L +   G  + R    G+ + L +
Sbjct: 528  SFRLVAYYTLIGASGQREVVADSVWVDVK-DSCVGSLVVK-SGQSEDRQPVPGQQMTLKI 585

Query: 592  ETDSLALVALGALDTALYAAGSKSHKPLNMGKVFEAMNSYDLGCGPGGGDSALQVFQAAG 651
            E D  A V L A+D  ++    K+   L   K+++ +   D+GC PG G     VF  AG
Sbjct: 586  EGDHGARVVLVAVDKGVFVLNKKNK--LTQSKIWDVVEKADIGCTPGSGKDYAGVFSDAG 643

Query: 652  LAF-SDGDQWTLSRKRLSCPKEKTTRKKRNVNFQKAINEKLGQYASPTAKRCCQDGVTRL 710
            L F S   Q T  R  L CP +   R++R+V   +   +K+G+Y     K CC+DG+   
Sbjct: 644  LTFTSSSGQQTAQRAELQCP-QPAARRRRSVQLTEKRMDKVGKYPKELRK-CCEDGMREN 701

Query: 711  PMMRSCEQRAARVQQPD-CREPFLSCCQFAESLRKKSRDKGQAGLQRALEILQEEDLIDE 769
            PM  SC++R   +   + C++ FL CC +   LR++       GL R+     +ED+I E
Sbjct: 702  PMRFSCQRRTRFISLGEACKKVFLDCCNYITELRRQHARASHLGLARSN---LDEDIIAE 758

Query: 770  DDIPVRSFFPENWLWRVETVDR-------FQILTLWLPDSLTTWEIHGLSLSKTKGLCVA 822
            ++I  RS FPE+WLW VE +          +++ ++L DS+TTWEI  +S+S  KG+CVA
Sbjct: 759  ENIVSRSEFPESWLWNVEDLKEPPKNGISTKLMNIFLKDSITTWEILAVSMSDKKGICVA 818

Query: 823  TPVQLRVFREFHLHLRLPMSVRRFEQLELRPVLYNYL-DKNLTVSVHVSPVEGLC-LAGG 880
             P ++ V ++F + LRLP SV R EQ+E+R VLYNY  ++ L V V +      C LA  
Sbjct: 819  DPFEVTVMQDFFIDLRLPYSVVRNEQVEIRAVLYNYRQNQELKVRVELLHNPAFCSLATT 878

Query: 881  GGLAQQ-VLVPAGSARPVAFSVVPTAAAAVSLKVVARGSFEFPVGDAVSKVLQIEKEGA- 938
                QQ V +P  S+  V + +VP       ++V A     F + D V K L++  EG  
Sbjct: 879  KRRHQQTVTIPPKSSLSVPYVIVPLKTGLQEVEVKAAVYHHF-ISDGVRKSLKVVPEGIR 937

Query: 939  IHREELVYELNP--LDHRGRTLE-IPGNSDPNMIPDGDFNSYVRVTASDPLDTLGSEGAL 995
            +++   V  L+P  L   G   E IP     + +PD +  + + +  + P+  + +E A+
Sbjct: 938  MNKTVAVRTLDPERLGREGVQKEDIPPADLSDQVPDTESETRILLQGT-PVAQM-TEDAV 995

Query: 996  SPGGVASLLRLPRGCGEQTMIYLAPTLAASRYLDKTEQWSTLPPETKDHAVDLIQKGYMR 1055
                +  L+  P GCGEQ MI + PT+ A  YLD+TEQW     E +  A++LI+KGY +
Sbjct: 996  DAERLKHLIVTPSGCGEQNMIGMTPTVIAVHYLDETEQWEKFGLEKRQGALELIKKGYTQ 1055

Query: 1056 IQQFRKADGSYAAWLSRDSSTWLTAFVLKVLSLAQEQVGGSPEKLQETSNWL-LSQQQAD 1114
               FR+   ++AA++ R  STWLTA+V+KV SLA   +    + L     WL L +Q+ D
Sbjct: 1056 QLAFRQPSSAFAAFVKRAPSTWLTAYVVKVFSLAVNLIAIDSQVLCGAVKWLILEKQKPD 1115

Query: 1115 GSFQDPCPVLDRSMQGGLVGNDET-VALTAFVTIALHHGLAVFQDEGAEPLKQRVEASIS 1173
            G FQ+  PV+ + M GGL  N+E  +ALTAFV I+L     + +++        +  SI+
Sbjct: 1116 GVFQEDAPVIHQEMIGGLRNNNEKDMALTAFVLISLQEAKDICEEQ-----VNSLPGSIT 1170

Query: 1174 KANSFLGEKASAGLLGAHAAAITAYALTLTKAPVDLLGVAHNNLMAMAQETGDNLYWGSV 1233
            KA  FL E     L  ++  AI  YAL                              G +
Sbjct: 1171 KAGDFL-EANYMNLQRSYTVAIAGYALA---------------------------QMGRL 1202

Query: 1234 TGSQSNAVSPTPAPRNPSDPMPQAPALWIETTAYALLHLLLHEGKAEMADQAAAWLTRQG 1293
             G   N    T   +N  +  P      +E T+YALL LL  +   +       WL  Q 
Sbjct: 1203 KGPLLNKFLTTAKDKNRWED-PGKQLYNVEATSYALLALLQLKD-FDFVPPVVRWLNEQR 1260

Query: 1294 SFQGGFRSTQDTVIALDALSAYWIASHTTEERGLNVTLSSTGRNGFKSHALQLNNRQIRG 1353
             + GG+ STQ T +   AL+ Y   +   +E  L+V+L    R+   +H +   +  +  
Sbjct: 1261 YYGGGYGSTQATFMVFQALAQYQKDAPDHQELNLDVSLQLPSRSSKITHRIHWESASLLR 1320

Query: 1354 LEEELQFSLGSKINVKVGGNSKGTLKVLRTYNVLDMKNTTCQDLQIEVTVKGHVEYTMEA 1413
             EE  +        V   G  +GTL V+  Y+       TC    ++VT+K         
Sbjct: 1321 SEETKE---NEGFTVTAEGKGQGTLSVVTMYHAKAKDQLTCNKFDLKVTIK--------- 1368

Query: 1414 NEDYEDYEYDELPAKDDPDAPLQPVTPLQLFEGRRNRRRREAPKVVEEQESRVHYTVCIW 1473
                        PA +    P      + L    R R  ++A                  
Sbjct: 1369 ------------PAPETEKRPQDAKNTMILEICTRYRGDQDAT----------------- 1399

Query: 1474 RNGKVGLSGMAIADVTLLSGFHALRADLEKLTSLSDRYVSHFETEGPH-----VLLYFDS 1528
                     M+I D+++++GF     DL++L +  DRY+S +E +        +++Y D 
Sbjct: 1400 ---------MSILDISMMTGFAPDTDDLKQLANGVDRYISKYELDKAFSDRNTLIIYLDK 1450

Query: 1529 VPTSRE-CVGFEAVQEVPVGLVQPASATLYDYYNPERRCSVFYGAPSKSRLLATLCSAEV 1587
            V  S + C+ F+  Q   V L+QP +  +Y YYN E  C+ FY    +   L  LC  E+
Sbjct: 1451 VSHSEDDCLAFKVHQYFNVELIQPGAVKVYAYYNLEESCTRFYHPEKEDGKLNKLCRDEL 1510

Query: 1588 CQCAEGKCPRQRRALERGLQDEDGYRMKFACYYPRVEYGFQVKVLREDSRAAFRLFETKI 1647
            C+CAE  C  Q+   +  L++    R+  AC  P V+Y ++ ++++      F  +   I
Sbjct: 1511 CRCAEENCFIQKSDDKVTLEE----RLDKAC-EPGVDYVYKTRLVKVQLSNDFDEYIMAI 1565

Query: 1648 TQVLHFTKDVKAAANQMRNFLVRASCR--LRLEPGKEYLIMGLDGATYDLEGHPQYLLDS 1705
             Q +    D +    Q R F+    CR  L+LE  K YL+ GL    +  + +  Y++  
Sbjct: 1566 EQTIKSGSD-EVQVGQQRTFISPIKCREALKLEEKKHYLMWGLSSDFWGEKPNLSYIIGK 1624

Query: 1706 NSWIEEMPSERLCRSTRQRAACAQLNDFLQEYGTQGC 1742
            ++W+E  P E  C+    +  C  L  F +     GC
Sbjct: 1625 DTWVEHWPEEDECQDEENQKQCQDLGAFTESMVVFGC 1661


>gi|239754277 PREDICTED: similar to Complement component 4A (Rodgers
           blood group) [Homo sapiens]
          Length = 270

 Score =  531 bits (1368), Expect = e-150
 Identities = 265/265 (100%), Positives = 265/265 (100%)

Query: 86  SLQVPLKDAKSCGLHQLLRGPEVQLVAHSPWLKDSLSRTTNIQGINLLFSSRRGHLFLQT 145
           SLQVPLKDAKSCGLHQLLRGPEVQLVAHSPWLKDSLSRTTNIQGINLLFSSRRGHLFLQT
Sbjct: 6   SLQVPLKDAKSCGLHQLLRGPEVQLVAHSPWLKDSLSRTTNIQGINLLFSSRRGHLFLQT 65

Query: 146 DQPIYNPGQRVRYRVFALDQKMRPSTDTITVMVENSHGLRVRKKEVYMPSSIFQDDFVIP 205
           DQPIYNPGQRVRYRVFALDQKMRPSTDTITVMVENSHGLRVRKKEVYMPSSIFQDDFVIP
Sbjct: 66  DQPIYNPGQRVRYRVFALDQKMRPSTDTITVMVENSHGLRVRKKEVYMPSSIFQDDFVIP 125

Query: 206 DISEPGTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKITPGKPYILTVPGHLDEMQLD 265
           DISEPGTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKITPGKPYILTVPGHLDEMQLD
Sbjct: 126 DISEPGTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKITPGKPYILTVPGHLDEMQLD 185

Query: 266 IQARYIYGKPVQGVAYVRFGLLDEDGKKTFFRGLESQTKLVNGQSHISLSKAEFQDALEK 325
           IQARYIYGKPVQGVAYVRFGLLDEDGKKTFFRGLESQTKLVNGQSHISLSKAEFQDALEK
Sbjct: 186 IQARYIYGKPVQGVAYVRFGLLDEDGKKTFFRGLESQTKLVNGQSHISLSKAEFQDALEK 245

Query: 326 LNMGITDLQGLRLYVAAAIIEYPGG 350
           LNMGITDLQGLRLYVAAAIIEYPGG
Sbjct: 246 LNMGITDLQGLRLYVAAAIIEYPGG 270


>gi|169218213 PREDICTED: similar to complement component C3, partial
            [Homo sapiens]
          Length = 1295

 Score =  520 bits (1338), Expect = e-147
 Identities = 398/1222 (32%), Positives = 614/1222 (50%), Gaps = 98/1222 (8%)

Query: 132  LLFSSRRGHLFLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTITVMVENSHGLRVRKKEV 191
            +L S + G+LF+QTD+ IY PG  V YR+F ++ K+ P   T+ V +EN  G+ V++  +
Sbjct: 121  VLVSLQSGYLFIQTDKTIYTPGSTVLYRIFTVNHKLLPVGRTVMVNIENPEGIPVKQDSL 180

Query: 192  YMPSS--IFQDDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKITPGK 249
               +   +    + IP++   G WKI A + +  +   ST+FEVK+YVLP+FEV + P +
Sbjct: 181  SSQNQLGVLPLSWDIPELVNMGQWKIRAYYENSPQQVFSTEFEVKEYVLPSFEVIVEPTE 240

Query: 250  P--YILTVPGHLDEMQLDIQARYIYGKPVQGVAYVRFGLLDEDGKKTFFRGLESQTKLVN 307
               YI    G    +++ I AR++YGK V+G A+V FG+ D + + +    L+ +  + +
Sbjct: 241  KFYYIYNEKG----LEVTITARFLYGKKVEGTAFVIFGIQDGEQRISLPESLK-RIPIED 295

Query: 308  GQSHISLSKAEFQDALEKLNMGITDLQGLRLYVAAAIIEYPGGEMEEAELTSWYFVSSPF 367
            G   + LS+    D ++  N+   DL G  LYV+A +I + G +M +AE +    V+SP+
Sbjct: 296  GSGEVVLSRKVLLDGVQ--NLRAEDLVGKSLYVSATVILHSGSDMVQAERSGIPIVTSPY 353

Query: 368  SLDLSKTKRHLVPGAPFLLQALVREMSGSPASGIPVKVSA--TVSSPGSVPEVQDIQQNT 425
             +  +KT ++  PG PF L   V    GSPA  +PV V    TV S      V  +  NT
Sbjct: 354  QIHFTKTPKYFKPGMPFDLMVFVTNPDGSPAYRVPVAVQGEDTVQSLTQGDGVAKLSINT 413

Query: 426  DGSGQVSIPIIIPQTISELQLSVSAGSPHPAIARLTVAAPPSGGPGFLSIEWPDSRPPRV 485
              S Q  + I +     EL  +  A     A+   TV    S     LS+   + RP   
Sbjct: 414  HPS-QKPLSITVRTKKQELSEAEQATRTMQALPYSTVGN--SNNYLHLSVLRTELRP--- 467

Query: 486  GDTLNLNLRAV---GSGATFSHYYYMILSRGQIVFMNR---EPKRTLTSVSVFVDHHLAP 539
            G+TLN+N          A   +Y Y+I+++G+++   R   EP + L  + + +     P
Sbjct: 468  GETLNVNFLLRMDRAHEAKIRYYTYLIMNKGRLLKAGRQVREPGQDLVVLPLSITTDFIP 527

Query: 540  SFYFVAFYY----HGDHPV-ANSLRVDVQAGACEGKLELSVDGAKQYRN---GESVKLHL 591
            SF  VA+Y      G   V A+S+ VDV+  +C G L +   G  + R    G+ + L +
Sbjct: 528  SFRLVAYYTLIGASGQREVVADSVWVDVK-DSCVGSLVVK-SGQSEDRQPVPGQQMTLKI 585

Query: 592  ETDSLALVALGALDTALYAAGSKSHKPLNMGKVFEAMNSYDLGCGPGGGDSALQVFQAAG 651
            E D  A V L A+D  ++    K+   L   K+++ +   D+GC PG G     VF  AG
Sbjct: 586  EGDHGARVVLVAVDKGVFVLNKKNK--LTQSKIWDVVEKADIGCTPGSGKDYAGVFSDAG 643

Query: 652  LAF-SDGDQWTLSRKRLSCPKEKTTRKKRNVNFQKAINEKLGQYASPTAKRCCQDGVTRL 710
            L F S   Q T  R  L CP +   R++R+V   +   +K+G+Y     K CC+DG+   
Sbjct: 644  LTFTSSSGQQTAQRAELQCP-QPAARRRRSVQLTEKRMDKVGKYPKELRK-CCEDGMREN 701

Query: 711  PMMRSCEQRAARVQQPD-CREPFLSCCQFAESLRKKSRDKGQAGLQRALEILQEEDLIDE 769
            PM  SC++R   +   + C++ FL CC +   LR++       GL R+     +ED+I E
Sbjct: 702  PMRFSCQRRTRFISLGEACKKVFLDCCNYITELRRQHARASHLGLARSN---LDEDIIAE 758

Query: 770  DDIPVRSFFPENWLWRVETVDR-------FQILTLWLPDSLTTWEIHGLSLSKTKGLCVA 822
            ++I  RS FPE+WLW VE +          +++ ++L DS+TTWEI  +S+S  KG+CVA
Sbjct: 759  ENIVSRSEFPESWLWNVEDLKEPPKNGISTKLMNIFLKDSITTWEILAVSMSDKKGICVA 818

Query: 823  TPVQLRVFREFHLHLRLPMSVRRFEQLELRPVLYNYL-DKNLTVSVHVSPVEGLC-LAGG 880
             P ++ V ++F + LRLP SV R EQ+E+R VLYNY  ++ L V V +      C LA  
Sbjct: 819  DPFEVTVMQDFFIDLRLPYSVVRNEQVEIRAVLYNYRQNQELKVRVELLHNPAFCSLATT 878

Query: 881  GGLAQQ-VLVPAGSARPVAFSVVPTAAAAVSLKVVARGSFEFPVGDAVSKVLQIEKEGA- 938
                QQ V +P  S+  V + +VP       ++V A     F + D V K L++  EG  
Sbjct: 879  KRRHQQTVTIPPKSSLSVPYVIVPLKTGLQEVEVKAAVYHHF-ISDGVRKSLKVVPEGIR 937

Query: 939  IHREELVYELNP--LDHRGRTLE-IPGNSDPNMIPDGDFNSYVRVTASDPLDTLGSEGAL 995
            +++   V  L+P  L   G   E IP     + +PD +  + + +  + P+  + +E A+
Sbjct: 938  MNKTVAVRTLDPERLGREGVQKEDIPPADLSDQVPDTESETRILLQGT-PVAQM-TEDAV 995

Query: 996  SPGGVASLLRLPRGCGEQTMIYLAPTLAASRYLDKTEQWSTLPPETKDHAVDLIQKGYMR 1055
                +  L+  P GCGEQ MI + PT+ A  YLD+TEQW     E +  A++LI+KGY +
Sbjct: 996  DAERLKHLIVTPSGCGEQNMIGMTPTVIAVHYLDETEQWEKFGLEKRQGALELIKKGYTQ 1055

Query: 1056 IQQFRKADGSYAAWLSRDSSTWLTAFVLKVLSLAQEQVGGSPEKLQETSNWL-LSQQQAD 1114
               FR+   ++AA++ R  STWLTA+V+KV SLA   +    + L     WL L +Q+ D
Sbjct: 1056 QLAFRQPSSAFAAFVKRAPSTWLTAYVVKVFSLAVNLIAIDSQVLCGAVKWLILEKQKPD 1115

Query: 1115 GSFQDPCPVLDRSMQGGLVGNDET-VALTAFVTIALHHGLAVFQDEGAEPLKQRVEASIS 1173
            G FQ+  PV+ + M GGL  N+E  +ALTAFV I+L     + +++        +  SI+
Sbjct: 1116 GVFQEDAPVIHQEMIGGLRNNNEKDMALTAFVLISLQEAKDICEEQ-----VNSLPGSIT 1170

Query: 1174 KANSFLGEKASAGLLGAHAAAITAYALTLTKAPVDLLGVAHNNLMAMAQETGDNLYWGSV 1233
            KA  FL E     L  ++  AI  YAL                              G +
Sbjct: 1171 KAGDFL-EANYMNLQRSYTVAIAGYALA---------------------------QMGRL 1202

Query: 1234 TGSQSNAVSPTPAPRNPSDPMPQAPALWIETTAYALLHLLLHEGKAEMADQAAAWLTRQG 1293
             G   N    T   +N  +  P      +E T+YALL LL  +   +       WL  Q 
Sbjct: 1203 KGPLLNKFLTTAKDKNRWED-PGKQLYNVEATSYALLALLQLKD-FDFVPPVVRWLNEQR 1260

Query: 1294 SFQGGFRSTQDTVIALDALSAY 1315
             + GG+ STQ T +   AL+ Y
Sbjct: 1261 YYGGGYGSTQATFMVFQALAQY 1282


>gi|38016947 complement component 5 preproprotein [Homo sapiens]
          Length = 1676

 Score =  517 bits (1331), Expect = e-146
 Identities = 447/1660 (26%), Positives = 750/1660 (45%), Gaps = 163/1660 (9%)

Query: 139  GHLFLQTDQPIYNPGQRVRYRVFALDQKMRPST-DTITVMVENSHGLRVRKKEVYMPSSI 197
            G LF+ TD+P+Y P Q V+ RV++L+  ++P+  +T+   ++         +E+     I
Sbjct: 124  GFLFIHTDKPVYTPDQSVKVRVYSLNDDLKPAKRETVLTFIDPEGSEVDMVEEIDHIGII 183

Query: 198  FQDDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKITPGKPYILTVPG 257
               DF IP     G W I A++ +   +  +  FEVK+YVLP+F V I P   Y      
Sbjct: 184  SFPDFKIPSNPRYGMWTIKAKYKEDFSTTGTAYFEVKEYVLPHFSVSIEP--EYNFIGYK 241

Query: 258  HLDEMQLDIQARYIYGKPV-QGVAYVRFGLLDE--DGKKTFFRGLESQTKLVNGQSHISL 314
            +    ++ I+ARY Y K V +   Y+ FG+ ++  D +K   +     T L+NG + ++ 
Sbjct: 242  NFKNFEITIKARYFYNKVVTEADVYITFGIREDLKDDQKEMMQTAMQNTMLINGIAQVTF 301

Query: 315  SKAEFQDALEKLNM-GITDLQGLRLYVAAAIIEYPGGEMEEAELTSWYFVSSPFSLDLSK 373
                 + A+++L+   + DL    LY+A  +IE  GG  EEAE+    +V SP+ L+L  
Sbjct: 302  DS---ETAVKELSYYSLEDLNNKYLYIAVTVIESTGGFSEEAEIPGIKYVLSPYKLNLVA 358

Query: 374  TKRHLVPGAPFLLQALVREMSGSPASGIPVKVSATVSSPGSVPEVQDIQQNTD----GSG 429
            T   L PG P+ ++  V++       G+PV ++A         E  D+  +        G
Sbjct: 359  TPLFLKPGIPYPIKVQVKDSLDQLVGGVPVTLNAQTIDVNQ--ETSDLDPSKSVTRVDDG 416

Query: 430  QVSIPIIIPQTISELQLSVSAGSP-----HPAIARLTVAAPPSGGPGFLSIEWPDSRPPR 484
              S  + +P  ++ L+ +V   +P     + A       A  S    +L I+W D+    
Sbjct: 417  VASFVLNLPSGVTVLEFNVKTDAPDLPEENQAREGYRAIAYSSLSQSYLYIDWTDNHKAL 476

Query: 485  -VGDTLNLNLRAVGSGAT-FSHYYYMILSRGQIVFMNREPK---RTLTSVSVFVDHHLAP 539
             VG+ LN+ +          +HY Y+ILS+G+I+      K    +  S+++ V  ++ P
Sbjct: 477  LVGEHLNIIVTPKSPYIDKITHYNYLILSKGKIIHFGTREKFSDASYQSINIPVTQNMVP 536

Query: 540  SFYFVAFYY-HGDHP---VANSLRVDVQAGACEGKLELSVD-GAKQYRNGESVKLHLETD 594
            S   + +Y   G+     V++S+ ++++   C  +L++ +   A  Y  G++V L++ T 
Sbjct: 537  SSRLLVYYIVTGEQTAELVSDSVWLNIEE-KCGNQLQVHLSPDADAYSPGQTVSLNMATG 595

Query: 595  SLALVALGALDTALYAAGSKSHKPLNMGKVFEAMNSYDLGCGPGGGDSALQVFQAAGLAF 654
              + VAL A+D+A+Y     + KPL   +VF+ +   DLGCG GGG +   VF  AGL F
Sbjct: 596  MDSWVALAAVDSAVYGVQRGAKKPLE--RVFQFLEKSDLGCGAGGGLNNANVFHLAGLTF 653

Query: 655  SDGDQWTLSRKRLSCPKEKTTRKKRNVNFQKAINEKLGQYASPTAKRCCQDGVTRLPMMR 714
                    S++    P ++  R +R +  QK I E   +Y     K+CC DG   +    
Sbjct: 654  LTNANADDSQENDE-PCKEILRPRRTL--QKKIEEIAAKYKHSVVKKCCYDGAC-VNNDE 709

Query: 715  SCEQRAARVQQ-PDCREPFLSCCQFAESLRKKSRDKGQAGLQRALEILQEEDLIDEDDIP 773
            +CEQRAAR+   P C + F  CC  A  LR     K        L  L  + L+      
Sbjct: 710  TCEQRAARISLGPRCIKAFTECCVVASQLRANISHKDMQ-----LGRLHMKTLLPVSKPE 764

Query: 774  VRSFFPENWLWRVETVDRFQILTLWLPDSLTTWEIHGLSLSKTKGLCVATPVQLRVFREF 833
            +RS+FPE+WLW V  V R + L   LPDSLTTWEI G+ +S T G+CVA  V+ +VF++ 
Sbjct: 765  IRSYFPESWLWEVHLVPRRKQLQFALPDSLTTWEIQGVGISNT-GICVADTVKAKVFKDV 823

Query: 834  HLHLRLPMSVRRFEQLELRPVLYNYLDKNLTVSVHVSPVEGLCLAGGGGLAQQ------- 886
             L + +P SV R EQ++L+  +YNY    +   V +S VEG+C +    +  Q       
Sbjct: 824  FLEMNIPYSVVRGEQIQLKGTVYNYRTSGMQFCVKMSAVEGICTSESPVIDHQGTKSSKC 883

Query: 887  --VLVPAGSARPVAFSVVPTAAAAVSLKVVARGSFEFPVG-DAVSKVLQIEKEGAIHREE 943
                V   S+  V F+V+P      ++      S E   G + + K L++  EG + RE 
Sbjct: 884  VRQKVEGSSSHLVTFTVLPLEIGLHNINF----SLETWFGKEILVKTLRVVPEG-VKRES 938

Query: 944  LVYELNPLDHRG------RTLEIPGNSDPNMIPDGDFNSYVRVTASDPLDTLGSEGALSP 997
              Y    LD RG      R  E P     +++P  +    + V      + L +   LS 
Sbjct: 939  --YSGVTLDPRGIYGTISRRKEFPYRIPLDLVPKTEIKRILSVKGLLVGEILSA--VLSQ 994

Query: 998  GGVASLLRLPRGCGEQTMIYLAPTLAASRYLDKTEQWSTL---PPETKDHAVDLIQKGYM 1054
             G+  L  LP+G  E  ++ + P      YL+    W+     P   K      +++G +
Sbjct: 995  EGINILTHLPKGSAEAELMSVVPVFYVFHYLETGNHWNIFHSDPLIEKQKLKKKLKEGML 1054

Query: 1055 RIQQFRKADGSYAAWLSRDSSTWLTAFVLKVLSLAQEQVGGSPEKLQETSNWLLSQQQAD 1114
             I  +R AD SY+ W    +STWLTAF L+VL    + V  +   +  +  WL+   Q D
Sbjct: 1055 SIMSYRNADYSYSVWKGGSASTWLTAFALRVLGQVNKYVEQNQNSICNSLLWLVENYQLD 1114

Query: 1115 -GSFQDPCPVLDRSMQGGL--VGNDETVALTAFVTIALHHGLAVFQDEGAEPLKQRVEAS 1171
             GSF++        +QG L     + ++ LTAF  I +     +       PL  +++ +
Sbjct: 1115 NGSFKENSQYQPIKLQGTLPVEARENSLYLTAFTVIGIRKAFDIC------PL-VKIDTA 1167

Query: 1172 ISKANSFLGEKASAGLLGAHAAAITAYALTLTKAPVDLLGVAHNNLMAMAQETGD---NL 1228
            + KA++FL E  +         AI+AYAL+L            + L   A   G+     
Sbjct: 1168 LIKADNFLLEN-TLPAQSTFTLAISAYALSLGDKTHPQFRSIVSALKREALVKGNPPIYR 1226

Query: 1229 YWGSVTGSQSNAVSPTPAPRNPSDPMPQAPALWIETTAYALLHLLLHEGKAEMADQAAAW 1288
            +W      + ++V  T   R             +ETTAYALL   L+       +    W
Sbjct: 1227 FWKDNLQHKDSSVPNTGTAR------------MVETTAYALL-TSLNLKDINYVNPVIKW 1273

Query: 1289 LTRQGSFQGGFRSTQDTVIALDALSAYWIASHTTEERGLNVTLSSTGRNGFKSHALQLNN 1348
            L+ +  + GGF STQDT+ A++ L+ Y   S   ++  L++ +  + ++    H  ++ +
Sbjct: 1274 LSEEQRYGGGFYSTQDTINAIEGLTEY---SLLVKQLRLSMDIDVSYKHKGALHNYKMTD 1330

Query: 1349 RQIRGLEEELQFSLGSKINVKVG-GNSKGTLKVLRTYNVLDMKNTTCQ-DLQIEVTVKGH 1406
            +   G    ++  L   + V  G G+   T+ V    +        C   L+I+      
Sbjct: 1331 KNFLG--RPVEVLLNDDLIVSTGFGSGLATVHVTTVVHKTSTSEEVCSFYLKIDTQDIEA 1388

Query: 1407 VEYTMEANEDYEDYEYDELPAKDDPDAPLQPVTPLQLFEGRRNRRRREAPKVVEEQESRV 1466
              Y    N DY                  + +     ++  R           EE  S  
Sbjct: 1389 SHYRGYGNSDY------------------KRIVACASYKPSR-----------EESSSG- 1418

Query: 1467 HYTVCIWRNGKVGLSGMAIADVTLLSGFHALRADLEKLTSLSDRYVSHFETEGPHVLLYF 1526
                          S  A+ D++L +G  A   DL+ L    D+  + ++ +  HV+L  
Sbjct: 1419 --------------SSHAVMDISLPTGISANEEDLKALVEGVDQLFTDYQIKDGHVILQL 1464

Query: 1527 DSVPTSR-ECVGFEAVQEVPVGLVQPASATLYDYYNPERRCSVFYGAPSKSRLLATLCSA 1585
            +S+P+S   CV F   +   VG + PA+ T+Y+Y+ P+++C++FY   + +  +  +C  
Sbjct: 1465 NSIPSSDFLCVRFRIFELFEVGFLSPATFTVYEYHRPDKQCTMFYS--TSNIKIQKVCEG 1522

Query: 1586 EVCQCAEGKCPRQRRALERGLQDEDGYRMKFACYYPRVEYGFQVKVLREDSRAAFRLFET 1645
              C+C E  C + +  L+  +  E   R + AC  P + Y ++V +        F  ++ 
Sbjct: 1523 AACKCVEADCGQMQEELDLTISAET--RKQTAC-KPEIAYAYKVSITSITVENVFVKYKA 1579

Query: 1646 KITQVLHFTKDVKAAANQMRNFLVRASC-RLRLEPGKEYLIMGLDG--ATYDLEGHPQYL 1702
             +  + + T +  A  +    F+ + +C    L  G++YLIMG +     Y+      Y 
Sbjct: 1580 TLLDI-YKTGEAVAEKDSEITFIKKVTCTNAELVKGRQYLIMGKEALQIKYNFSFRYIYP 1638

Query: 1703 LDSNSWIEEMPSERLCRSTRQRAACAQLNDFLQEYGTQGC 1742
            LDS +WIE  P +  C S   +A  A L++F ++    GC
Sbjct: 1639 LDSLTWIEYWPRDTTCSSC--QAFLANLDEFAEDIFLNGC 1676


>gi|66932947 alpha-2-macroglobulin precursor [Homo sapiens]
          Length = 1474

 Score =  296 bits (759), Expect = 9e-80
 Identities = 381/1505 (25%), Positives = 611/1505 (40%), Gaps = 229/1505 (15%)

Query: 141  LFLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTIT-VMVENSHGLRVRKKEVYMPSSIFQ 199
            +F+QTD+ IY PGQ V++RV ++D+   P  + I  V +++  G R+ + + +      +
Sbjct: 129  VFVQTDKSIYKPGQTVKFRVVSMDENFHPLNELIPLVYIQDPKGNRIAQWQSFQLEGGLK 188

Query: 200  DDFVIPDISEP--GTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKITPGKPYILTVPG 257
              F  P  SEP  G++K+  +   G    +   F V+++VLP FEV++T   P I+T+  
Sbjct: 189  Q-FSFPLSSEPFQGSYKVVVQKKSG--GRTEHPFTVEEFVLPKFEVQVTV--PKIITILE 243

Query: 258  HLDEMQLDIQARYIYGKPVQGVAYVRFGLLDEDGKKTFFRGLESQTKLVNGQSHISLSKA 317
              +EM + +   Y YGKPV G  +V   +  +    +   G +SQ         ++    
Sbjct: 244  --EEMNVSVCGLYTYGKPVPG--HVTVSICRKYSDASDCHGEDSQAFCEKFSGQLNSHGC 299

Query: 318  EFQDALEKLNMGITDLQGLRLYVAAAIIEYPGGEMEEAELTSWYFVSSPFSLDLSKTKRH 377
             +Q    K+         ++L+  A I E  G  +E     S     +   L   K   H
Sbjct: 300  FYQQVKTKVFQLKRKEYEMKLHTEAQIQE-EGTVVELTGRQSSEITRTITKLSFVKVDSH 358

Query: 378  LVPGAPFLLQALVREMSGSPASGIPVKVSATVSSPGSVPEVQDIQQNTDGSGQVSIPIII 437
               G PF  Q  + +  G P   IP KV     +  +          TD  G V   I  
Sbjct: 359  FRQGIPFFGQVRLVDGKGVP---IPNKVIFIRGNEANYYS----NATTDEHGLVQFSINT 411

Query: 438  PQTI-SELQLSVSAGSPHPAI-----------ARLTVAAPPSGGPGFLSIEWPDSRPPRV 485
               + + L + V+     P             A  T     S    F+ +E P S     
Sbjct: 412  TNVMGTSLTVRVNYKDRSPCYGYQWVSEEHEEAHHTAYLVFSPSKSFVHLE-PMSHELPC 470

Query: 486  GDTLNLNLRAVGSGATFS-----HYYYMILSRGQIV-------FMNREPKRTLTSVSVFV 533
            G T  +    + +G T        +YY+I+++G IV        + +E  +   S+S+ V
Sbjct: 471  GHTQTVQAHYILNGGTLLGLKKLSFYYLIMAKGGIVRTGTHGLLVKQEDMKGHFSISIPV 530

Query: 534  DHHLAP--SFYFVAFYYHGDHPVANSLRVDVQAGACEGKLELSVDGAKQYRNGESVKLHL 591
               +AP       A    GD  + +S + DV+      K++LS   + Q        L +
Sbjct: 531  KSDIAPVARLLIYAVLPTGD-VIGDSAKYDVE-NCLANKVDLSFSPS-QSLPASHAHLRV 587

Query: 592  ETDSLALVALGALDTALYAAGSKSHKPLNMGKVFEAMNSYDLGCGPGGGDSALQVFQAAG 651
                 ++ AL A+D ++     K    L+   V+  +   DL   PG  +          
Sbjct: 588  TAAPQSVCALRAVDQSVLLM--KPDAELSASSVYNLLPEKDLTGFPGPLND--------- 636

Query: 652  LAFSDGDQWTLSRKR-----LSCPKEKTTRKKRNVNFQKAINEKLGQYASPTAKRCCQDG 706
                  D+  ++R       ++     +T +K   +F     E +G  A   +K      
Sbjct: 637  ----QDDEDCINRHNVYINGITYTPVSSTNEKDMYSFL----EDMGLKAFTNSK------ 682

Query: 707  VTRLPMMRSCEQRAARVQQPDCREPFLSCCQFAESLRKKSRDKGQAGLQRALEILQEEDL 766
              R P M  C Q    +QQ +   P        E LR    +    G   A  +  EE  
Sbjct: 683  -IRKPKM--CPQ----LQQYEMHGP--------EGLRVGFYESDVMGRGHARLVHVEEPH 727

Query: 767  IDEDDIPVRSFFPENWLWRVETVDRFQI--LTLWLPDSLTTWEIHGLSLSKTKGLCVATP 824
             +     VR +FPE W+W +  V+   +  + + +PD++T W+     LS+  GL +++ 
Sbjct: 728  TET----VRKYFPETWIWDLVVVNSAGVAEVGVTVPDTITEWKAGAFCLSEDAGLGISST 783

Query: 825  VQLRVFREFHLHLRLPMSVRRFEQLELRPVLYNYLDKNLTVSVHVSPVEGLCLAGGGGLA 884
              LR F+ F + L +P SV R E   L+  + NYL K + VSV +               
Sbjct: 784  ASLRAFQPFFVELTMPYSVIRGEAFTLKATVLNYLPKCIRVSVQLEASPAFLAVPVEKEQ 843

Query: 885  QQVLVPAGSARPVAFSVVPTAAAAVSLKVVARG-------SFEFPV------GDAVSKVL 931
                + A   + V+++V P +   V+  V A           E P        D V K L
Sbjct: 844  APHCICANGRQTVSWAVTPKSLGNVNFTVSAEALESQELCGTEVPSVPEHGRKDTVIKPL 903

Query: 932  QIEKEGAIHREELVYELNPLDHRGRTLEIPGNSDPNMIPDGDFNSYVRVTASDPLDTLGS 991
             +E EG + +E     L        + E+     PN++ +       R + S   D LGS
Sbjct: 904  LVEPEG-LEKETTFNSLLCPSGGEVSEELSLKLPPNVVEES-----ARASVSVLGDILGS 957

Query: 992  EGALSPGGVASLLRLPRGCGEQTMIYLAPTLAASRYLDKTEQWSTLPPETKDHAVDLIQK 1051
                +     +LL++P GCGEQ M+  AP +    YL++T+Q   L PE K  A+  +  
Sbjct: 958  ----AMQNTQNLLQMPYGCGEQNMVLFAPNIYVLDYLNETQQ---LTPEIKSKAIGYLNT 1010

Query: 1052 GYMRIQQFRKADGSYAAWLSR----DSSTWLTAFVLKVLSLAQEQVGGSPEKLQETSNWL 1107
            GY R   ++  DGSY+ +  R      +TWLTAFVLK  + A+  +      + +   WL
Sbjct: 1011 GYQRQLNYKHYDGSYSTFGERYGRNQGNTWLTAFVLKTFAQARAYIFIDEAHITQALIWL 1070

Query: 1108 LSQQQADGSFQDPCPVLDRSMQGGLVGNDETVALTAFVTIALHH-GLAVFQDEGAEPLKQ 1166
              +Q+ +G F+    +L+ +++GG+   ++ V L+A++TIAL    L V       P+ +
Sbjct: 1071 SQRQKDNGCFRSSGSLLNNAIKGGV---EDEVTLSAYITIALLEIPLTV-----THPVVR 1122

Query: 1167 RVEASISKANSFLGEKASAGLLGAHA--AAITAYALTLTKAPVDLLGVAHNNLMAMAQET 1224
                 +  A     + A  G  G+H    A+ AYA  L     D       +L   A + 
Sbjct: 1123 NALFCLESA----WKTAQEGDHGSHVYTKALLAYAFALA-GNQDKRKEVLKSLNEEAVKK 1177

Query: 1225 GDNLYWGSVTGSQSNAVSPTPAPRNPSDPM-----PQAPALWIETTAYALLHLLLHEGKA 1279
             ++++W                P+ P  P+     PQAP+  +E T+Y LL  L  +   
Sbjct: 1178 DNSVHW--------------ERPQKPKAPVGHFYEPQAPSAEVEMTSYVLLAYLTAQPAP 1223

Query: 1280 EMADQAAA-----WLTRQGSFQGGFRSTQDTVIALDALSAYWIASHTTEERGLNVTLSST 1334
               D  +A     W+T+Q + QGGF STQDTV+AL ALS Y  A+ T   +   VT+ S+
Sbjct: 1224 TSEDLTSATNIVKWITKQQNAQGGFSSTQDTVVALHALSKYGAATFTRTGKAAQVTIQSS 1283

Query: 1335 GRNGFKSHALQLNNRQIRGLEEELQFSLGSKINVKVGGNSKGTLKVLRTYNVLDMKNTTC 1394
            G    K    Q++N     L++     L  + ++KV G     L+    YN+L  K    
Sbjct: 1284 GTFSSK---FQVDNNNRLLLQQVSLPELPGEYSMKVTGEGCVYLQTSLKYNILPEKEEFP 1340

Query: 1395 QDLQIEVTVKGHVEYTMEANEDYEDYEYDELPAK-DDPDAPLQPVTPLQLFEGRRNRRRR 1453
              L ++                        LP   D+P A     T  Q+          
Sbjct: 1341 FALGVQT-----------------------LPQTCDEPKAH----TSFQI---------- 1363

Query: 1454 EAPKVVEEQESRVHYTVCIWRNGKVGLSGMAIADVTLLSGFHALRADLEKLTSLSDRYVS 1513
                        V YT      G    S MAI DV ++SGF  L+  ++ L      +VS
Sbjct: 1364 ---------SLSVSYT------GSRSASNMAIVDVKMVSGFIPLKPTVKMLE--RSNHVS 1406

Query: 1514 HFETEGPHVLLYFDSVPTSRECVGFEAVQEVPVGLVQPASATLYDYYNPERRCSVFYGAP 1573
              E    HVL+Y D V      + F  +Q+VPV  ++PA   +YDYY  +      Y AP
Sbjct: 1407 RTEVSSNHVLIYLDKVSNQTLSLFFTVLQDVPVRDLKPAIVKVYDYYETDEFAIAEYNAP 1466

Query: 1574 SKSRL 1578
                L
Sbjct: 1467 CSKDL 1471


>gi|227430303 CD109 antigen isoform 3 precursor [Homo sapiens]
          Length = 1368

 Score =  239 bits (609), Expect = 2e-62
 Identities = 235/838 (28%), Positives = 361/838 (43%), Gaps = 123/838 (14%)

Query: 774  VRSFFPENWLWRVETVDR--FQILTLWLPDSLTTWEIHGLSLSKTKGL-CVATPVQLRVF 830
            VR  FPE W+W    +    +Q   + +PDS+T+W   G  +S+  GL    TPV+L+ F
Sbjct: 609  VRKHFPETWIWLDTNMGYRIYQEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVELQAF 668

Query: 831  REFHLHLRLPMSVRRFEQLELRPVLYNYLDKNLTVSVHVSPVEGLCLA------GGGGLA 884
            + F + L LP SV R E+  L   ++NYL     V V +   +   +          G  
Sbjct: 669  QPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEVKVIIEKSDKFDILMTSNEINATGHQ 728

Query: 885  QQVLVPAGSARPVAFSVVPTAAAAVSLKVVARGSFEFPVGDAVSKVLQIEKEGA--IHRE 942
            Q +LVP+     V F + PT    + + V A         DAV++++ ++ EG    + +
Sbjct: 729  QTLLVPSEDGATVLFPIRPTHLGEIPITVTALSP---TASDAVTQMILVKAEGIEKSYSQ 785

Query: 943  ELVYEL--NPLDHRGRTLEIPGNSDPNMIPDGDFNSYVRVTASDPLDTLGSEGALSPGGV 1000
             ++ +L  N L    +TL    +  PN +   +    V++TA    D LG     S  G+
Sbjct: 786  SILLDLTDNRLQSTLKTLSF--SFPPNTVTGSE---RVQITAIG--DVLGP----SINGL 834

Query: 1001 ASLLRLPRGCGEQTMIYLAPTLAASRYLDKTEQWSTLPPETKDHAVDLIQKGYMRIQQFR 1060
            ASL+R+P GCGEQ MI  AP +    YL K +Q   L    K+ A+  +++GY R   ++
Sbjct: 835  ASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQ---LTDNLKEKALSFMRQGYQRELLYQ 891

Query: 1061 KADGSYAAWLSRD--SSTWLTAFVLKVLSLAQEQVGGSPEKLQETSNWLLSQQQADGSFQ 1118
            + DGS++A+ + D   STWL+AFVL+    A   +      L  T  WL   Q+++G F 
Sbjct: 892  REDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDIDQNVLHRTYTWLKGHQKSNGEFW 951

Query: 1119 DPCPVLDRSMQGGLVGNDETVALTAFVTIALHHGLAVFQDEGAEPLKQRVEASISKANSF 1178
            DP  V+   +QG   GN   V LTA++  +L               K +    + ++  F
Sbjct: 952  DPGRVIHSELQG---GNKSPVTLTAYIVTSL-----------LGYRKYQPNIDVQESIHF 997

Query: 1179 LGEKASAGLLGAHAAAITAYALTLTKAPVDLLGVAHNNLMAMAQETGDNLYWGSVTGSQS 1238
            L  + S G+   +  A+  YAL+   +P      A N L   A++ G   +W S     S
Sbjct: 998  LESEFSRGISDNYTLALITYALSSVGSP--KAKEALNMLTWRAEQEGGMQFWVSSESKLS 1055

Query: 1239 NAVSPTPAPRNPSDPMPQAPALWIETTAYALLHLLLHEGKAEMADQAAAWLTRQGSFQGG 1298
            ++  P               +L IE  AYALL   L    +E       WL+RQ +  GG
Sbjct: 1056 DSWQPR--------------SLDIEVAAYALLSHFLQFQTSE-GIPIMRWLSRQRNSLGG 1100

Query: 1299 FRSTQDTVIALDALSAYWIASHTTEERGLNVTLSSTGRNGFKSHALQLNNRQIRGLEEEL 1358
            F STQDT +AL ALS +  A   TE   + VT++           +  +NR +     EL
Sbjct: 1101 FASTQDTTVALKALSEF-AALMNTERTNIQVTVTGPSSPSPVKFLIDTHNRLLL-QTAEL 1158

Query: 1359 QFSLGSKINVKVGGNSKGTLKVLRTYNVLDMKNTTCQDLQIEVTVKGHVEYTMEANEDYE 1418
                 + +N+   G      ++   YNV     ++ +   I+             N++  
Sbjct: 1159 AVVQPTAVNISANGFGFAICQLNVVYNV-KASGSSRRRRSIQ-------------NQEAF 1204

Query: 1419 DYEYDELPAKDDPDAPLQPVTPLQLFEGRRNRRRREAPKVVEEQESRVHYTVCIWRNGKV 1478
            D +      KDD                                 + V   VC   +G  
Sbjct: 1205 DLDVAVKENKDD--------------------------------LNHVDLNVCTSFSGP- 1231

Query: 1479 GLSGMAIADVTLLSGFHALRADLEKLTSLSDRYVSHFETEGPHVLLYFDSVPTSRECVGF 1538
            G SGMA+ +V LLSGF        +  SLS+  V   E +   + LY DSV  ++ CV  
Sbjct: 1232 GRSGMALMEVNLLSGFMV----PSEAISLSET-VKKVEYDHGKLNLYLDSVNETQFCVNI 1286

Query: 1539 EAVQEVPVGLVQPASATLYDYYNPERRCSVFYGAPSKSRLLATLCSAEVCQCAEGKCP 1596
             AV+   V   Q AS ++ DYY P R+    Y +  K      L S ++C   +G  P
Sbjct: 1287 PAVRNFKVSNTQDASVSIVDYYEPRRQAVRSYNSEVK------LSSCDLCSDVQGCRP 1338



 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 109/464 (23%), Positives = 187/464 (40%), Gaps = 49/464 (10%)

Query: 211 GTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKI-TPGKPYILTVPGHLDEMQLDIQAR 269
           G W I  + +D     S   F+V +YVLP FEV + TP   Y      HL+     I A+
Sbjct: 125 GDWSIQVQVNDQTYYQS---FQVSEYVLPKFEVTLQTP--LYCSMNSKHLNGT---ITAK 176

Query: 270 YIYGKPVQGVAYVRFGLLDEDGKKTFFRGLESQTKLVNGQSHISLSKAEFQDALEKLNMG 329
           Y YGKPV+G   + F  L   GKK       ++T  +NG ++ S +  E ++ ++  N G
Sbjct: 177 YTYGKPVKGDVTLTFLPLSFWGKKKNI----TKTFKINGSANFSFNDEEMKNVMDSSN-G 231

Query: 330 ITDLQGLR----LYVAAAIIEYPGGEMEEAELTSWYFVSSPFSLDLSKTKRHLVPGAPFL 385
           +++   L     + +   + E   G       T+ +F    + ++       L P   F 
Sbjct: 232 LSEYLDLSSPGPVEILTTVTESVTGISRNVS-TNVFFKQHDYIIEFFDYTTVLKPSLNFT 290

Query: 386 LQALVREMSGSP------ASGIPVKV---------SATVSSPGSVPEVQDIQQNTDGSGQ 430
               V    G+        + + + V         S + S    +  VQ I      SG 
Sbjct: 291 ATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAVQKINYTVPQSGT 350

Query: 431 VSIPIIIPQTISELQLSVSAGSPHPAIARLTVAAPPSGGPGFLSIEWPDSRPPRVGDTLN 490
             I   I +  SELQL         ++A  ++   PS    ++ ++  D    +VG    
Sbjct: 351 FKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFKSPS--KTYIQLKTRDEN-IKVGSPFE 407

Query: 491 LNLRAVGSGATFSHYYYMILSRGQIVFMNREPKRTLTSVSVFVDHHLAPSFYFVAFYYHG 550
           L    V          YM++SRGQ+V +    K+  T  S+  ++   P    + +Y   
Sbjct: 408 L---VVSGNKRLKELSYMVVSRGQLVAVG---KQNSTMFSLTPENSWTPKACVIVYYIED 461

Query: 551 D-HPVANSLRVDVQAGACEGKLELSVDGAKQYRNGESVKLHLE-TDSLALVALGALDTAL 608
           D   +++ L++ VQ    + K++L     K     E V L +  T   ++V + A+D ++
Sbjct: 462 DGEIISDVLKIPVQL-VFKNKIKLYWSKVKA-EPSEKVSLRISVTQPDSIVGIVAVDKSV 519

Query: 609 YAAGSKSHKPLNMGKVFEAMNSYDLGCGPGGGDSALQVFQAAGL 652
               + +   + M  V   +  Y+ G   G   ++  VFQ  GL
Sbjct: 520 NLMNASN--DITMENVVHELELYNTGYYLGMFMNSFAVFQECGL 561


>gi|115529484 CD109 antigen isoform 1 precursor [Homo sapiens]
          Length = 1445

 Score =  239 bits (609), Expect = 2e-62
 Identities = 235/838 (28%), Positives = 361/838 (43%), Gaps = 123/838 (14%)

Query: 774  VRSFFPENWLWRVETVDR--FQILTLWLPDSLTTWEIHGLSLSKTKGL-CVATPVQLRVF 830
            VR  FPE W+W    +    +Q   + +PDS+T+W   G  +S+  GL    TPV+L+ F
Sbjct: 686  VRKHFPETWIWLDTNMGYRIYQEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVELQAF 745

Query: 831  REFHLHLRLPMSVRRFEQLELRPVLYNYLDKNLTVSVHVSPVEGLCLA------GGGGLA 884
            + F + L LP SV R E+  L   ++NYL     V V +   +   +          G  
Sbjct: 746  QPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEVKVIIEKSDKFDILMTSNEINATGHQ 805

Query: 885  QQVLVPAGSARPVAFSVVPTAAAAVSLKVVARGSFEFPVGDAVSKVLQIEKEGA--IHRE 942
            Q +LVP+     V F + PT    + + V A         DAV++++ ++ EG    + +
Sbjct: 806  QTLLVPSEDGATVLFPIRPTHLGEIPITVTALSP---TASDAVTQMILVKAEGIEKSYSQ 862

Query: 943  ELVYEL--NPLDHRGRTLEIPGNSDPNMIPDGDFNSYVRVTASDPLDTLGSEGALSPGGV 1000
             ++ +L  N L    +TL    +  PN +   +    V++TA    D LG     S  G+
Sbjct: 863  SILLDLTDNRLQSTLKTLSF--SFPPNTVTGSE---RVQITAIG--DVLGP----SINGL 911

Query: 1001 ASLLRLPRGCGEQTMIYLAPTLAASRYLDKTEQWSTLPPETKDHAVDLIQKGYMRIQQFR 1060
            ASL+R+P GCGEQ MI  AP +    YL K +Q   L    K+ A+  +++GY R   ++
Sbjct: 912  ASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQ---LTDNLKEKALSFMRQGYQRELLYQ 968

Query: 1061 KADGSYAAWLSRD--SSTWLTAFVLKVLSLAQEQVGGSPEKLQETSNWLLSQQQADGSFQ 1118
            + DGS++A+ + D   STWL+AFVL+    A   +      L  T  WL   Q+++G F 
Sbjct: 969  REDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDIDQNVLHRTYTWLKGHQKSNGEFW 1028

Query: 1119 DPCPVLDRSMQGGLVGNDETVALTAFVTIALHHGLAVFQDEGAEPLKQRVEASISKANSF 1178
            DP  V+   +QG   GN   V LTA++  +L               K +    + ++  F
Sbjct: 1029 DPGRVIHSELQG---GNKSPVTLTAYIVTSL-----------LGYRKYQPNIDVQESIHF 1074

Query: 1179 LGEKASAGLLGAHAAAITAYALTLTKAPVDLLGVAHNNLMAMAQETGDNLYWGSVTGSQS 1238
            L  + S G+   +  A+  YAL+   +P      A N L   A++ G   +W S     S
Sbjct: 1075 LESEFSRGISDNYTLALITYALSSVGSP--KAKEALNMLTWRAEQEGGMQFWVSSESKLS 1132

Query: 1239 NAVSPTPAPRNPSDPMPQAPALWIETTAYALLHLLLHEGKAEMADQAAAWLTRQGSFQGG 1298
            ++  P               +L IE  AYALL   L    +E       WL+RQ +  GG
Sbjct: 1133 DSWQPR--------------SLDIEVAAYALLSHFLQFQTSE-GIPIMRWLSRQRNSLGG 1177

Query: 1299 FRSTQDTVIALDALSAYWIASHTTEERGLNVTLSSTGRNGFKSHALQLNNRQIRGLEEEL 1358
            F STQDT +AL ALS +  A   TE   + VT++           +  +NR +     EL
Sbjct: 1178 FASTQDTTVALKALSEF-AALMNTERTNIQVTVTGPSSPSPVKFLIDTHNRLLL-QTAEL 1235

Query: 1359 QFSLGSKINVKVGGNSKGTLKVLRTYNVLDMKNTTCQDLQIEVTVKGHVEYTMEANEDYE 1418
                 + +N+   G      ++   YNV     ++ +   I+             N++  
Sbjct: 1236 AVVQPTAVNISANGFGFAICQLNVVYNV-KASGSSRRRRSIQ-------------NQEAF 1281

Query: 1419 DYEYDELPAKDDPDAPLQPVTPLQLFEGRRNRRRREAPKVVEEQESRVHYTVCIWRNGKV 1478
            D +      KDD                                 + V   VC   +G  
Sbjct: 1282 DLDVAVKENKDD--------------------------------LNHVDLNVCTSFSGP- 1308

Query: 1479 GLSGMAIADVTLLSGFHALRADLEKLTSLSDRYVSHFETEGPHVLLYFDSVPTSRECVGF 1538
            G SGMA+ +V LLSGF        +  SLS+  V   E +   + LY DSV  ++ CV  
Sbjct: 1309 GRSGMALMEVNLLSGFMV----PSEAISLSET-VKKVEYDHGKLNLYLDSVNETQFCVNI 1363

Query: 1539 EAVQEVPVGLVQPASATLYDYYNPERRCSVFYGAPSKSRLLATLCSAEVCQCAEGKCP 1596
             AV+   V   Q AS ++ DYY P R+    Y +  K      L S ++C   +G  P
Sbjct: 1364 PAVRNFKVSNTQDASVSIVDYYEPRRQAVRSYNSEVK------LSSCDLCSDVQGCRP 1415



 Score =  100 bits (250), Expect = 9e-21
 Identities = 146/656 (22%), Positives = 270/656 (41%), Gaps = 67/656 (10%)

Query: 21  PRLLLFSPSVVHLGVPLSVGVQLQDVPRGQVVKGSVFLRNPSRNNVPCSPKVDFTLSSER 80
           PR L+ +P ++  G  +++GV+L +    QV   +  L+  S  N+  S      +  + 
Sbjct: 26  PRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKAELLKTAS--NLTVSVLEAEGVFEKG 83

Query: 81  DFALLSL-QVPLKDAKSCGLHQLLRGPEVQLVAHSPWLKDSLSRTTNIQGINLLFSSRRG 139
            F  L+L  +PL  A            E+  +  +   +D +  + + +   L F ++R 
Sbjct: 84  SFKTLTLPSLPLNSAD-----------EIYELRVTGRTQDEILFSNSTR---LSFETKRI 129

Query: 140 HLFLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTITVMVENSHGLRVRK-KEVYMPSSIF 198
            +F+QTD+ +Y P Q V++R+  L    +P   ++ +++++     +++         + 
Sbjct: 130 SVFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNILIKDPKSNLIQQWLSQQSDLGVI 189

Query: 199 QDDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKI-TPGKPYILTVPG 257
              F +      G W I  + +D     S   F+V +YVLP FEV + TP   Y      
Sbjct: 190 SKTFQLSSHPILGDWSIQVQVNDQTYYQS---FQVSEYVLPKFEVTLQTP--LYCSMNSK 244

Query: 258 HLDEMQLDIQARYIYGKPVQGVAYVRFGLLDEDGKKTFFRGLESQTKLVNGQSHISLSKA 317
           HL+     I A+Y YGKPV+G   + F  L   GKK       ++T  +NG ++ S +  
Sbjct: 245 HLNG---TITAKYTYGKPVKGDVTLTFLPLSFWGKKKNI----TKTFKINGSANFSFNDE 297

Query: 318 EFQDALEKLNMGITDLQGLR----LYVAAAIIEYPGGEMEEAELTSWYFVSSPFSLDLSK 373
           E ++ ++  N G+++   L     + +   + E   G       T+ +F    + ++   
Sbjct: 298 EMKNVMDSSN-GLSEYLDLSSPGPVEILTTVTESVTGISRNVS-TNVFFKQHDYIIEFFD 355

Query: 374 TKRHLVPGAPFLLQALVREMSGSP------ASGIPVKV---------SATVSSPGSVPEV 418
               L P   F     V    G+        + + + V         S + S    +  V
Sbjct: 356 YTTVLKPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAV 415

Query: 419 QDIQQNTDGSGQVSIPIIIPQTISELQLSVSAGSPHPAIARLTVAAPPSGGPGFLSIEWP 478
           Q I      SG   I   I +  SELQL         ++A  ++   PS    ++ ++  
Sbjct: 416 QKINYTVPQSGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFKSPS--KTYIQLKTR 473

Query: 479 DSRPPRVGDTLNLNLRAVGSGATFSHYYYMILSRGQIVFMNREPKRTLTSVSVFVDHHLA 538
           D    +VG    L    V          YM++SRGQ+V +    K+  T  S+  ++   
Sbjct: 474 DEN-IKVGSPFEL---VVSGNKRLKELSYMVVSRGQLVAVG---KQNSTMFSLTPENSWT 526

Query: 539 PSFYFVAFYYHGD-HPVANSLRVDVQAGACEGKLELSVDGAKQYRNGESVKLHLE-TDSL 596
           P    + +Y   D   +++ L++ VQ    + K++L     K     E V L +  T   
Sbjct: 527 PKACVIVYYIEDDGEIISDVLKIPVQL-VFKNKIKLYWSKVKA-EPSEKVSLRISVTQPD 584

Query: 597 ALVALGALDTALYAAGSKSHKPLNMGKVFEAMNSYDLGCGPGGGDSALQVFQAAGL 652
           ++V + A+D ++    + +   + M  V   +  Y+ G   G   ++  VFQ  GL
Sbjct: 585 SIVGIVAVDKSVNLMNASN--DITMENVVHELELYNTGYYLGMFMNSFAVFQECGL 638


>gi|162809334 pregnancy-zone protein [Homo sapiens]
          Length = 1482

 Score =  236 bits (602), Expect = 1e-61
 Identities = 225/833 (27%), Positives = 356/833 (42%), Gaps = 130/833 (15%)

Query: 774  VRSFFPENWLWRVETVDRFQI--LTLWLPDSLTTWEIHGLSLSKTKGLCVATPVQLRVFR 831
            VRS+FPE W+W +  V+   +  + + +PD++T W+     LS+  GL +++   LR F+
Sbjct: 737  VRSYFPETWIWELVAVNSSGVAEVGVTVPDTITEWKAGAFCLSEDAGLGISSTASLRAFQ 796

Query: 832  EFHLHLRLPMSVRRFEQLELRPVLYNYLDKNLTVSVHV--SPV----------EGLCLAG 879
             F + L +P SV R E   L+  + NYL K + VSV +  SP           E  C+ G
Sbjct: 797  PFFVELTMPYSVIRGEVFTLKATVLNYLPKCIRVSVQLKASPAFLASQNTKGEESYCICG 856

Query: 880  GGGLAQQVLVPAGSARPVAFSVVPTAAAAVSLKVVARGSFEFPV---GDAVSKVLQIEKE 936
                     V   +   V FSV  +A A  SL++      E P     D V K L +E E
Sbjct: 857  NERQTLSWTVTPKTLGNVNFSV--SAEAMQSLELCGNEVVEVPEIKRKDTVIKTLLVEAE 914

Query: 937  GAIHREELVYELNPLDHRGRTLEIPGNSDPNMIPDGDFNSYVRVTASDPLDTLGSEGALS 996
            G I +E+    +        + ++      N++ +       R + S   D LGS    +
Sbjct: 915  G-IEQEKTFSSMTCASGANVSEQLSLKLPSNVVKES-----ARASFSVLGDILGS----A 964

Query: 997  PGGVASLLRLPRGCGEQTMIYLAPTLAASRYLDKTEQWSTLPPETKDHAVDLIQKGYMRI 1056
               + +LL++P GCGEQ M+  AP +    YL++T+Q   L  E K  AV  +  GY R 
Sbjct: 965  MQNIQNLLQMPYGCGEQNMVLFAPNIYVLNYLNETQQ---LTQEIKAKAVGYLITGYQRQ 1021

Query: 1057 QQFRKADGSYAAWLSR----DSSTWLTAFVLKVLSLAQEQVGGSPEKLQETSNWLLSQQQ 1112
              ++  DGSY+ +  R      +TWLTAFVLK  + A+  +      + ++  WL   Q+
Sbjct: 1022 LNYKHQDGSYSTFGERYGRNQGNTWLTAFVLKTFAQARSYIFIDEAHITQSLTWLSQMQK 1081

Query: 1113 ADGSFQDPCPVLDRSMQGGLVGNDETVALTAFVTIALHHGLAVFQDEGAEPLKQRVEASI 1172
             +G F+    +L+ +++GG+   ++   L+A+VTIAL         E   P+   +  + 
Sbjct: 1082 DNGCFRSSGSLLNNAIKGGV---EDEATLSAYVTIALL--------EIPLPVTNPIVRNA 1130

Query: 1173 SKANSFLGEKASAGLLGAH--AAAITAYALTLTKAPVDLLGVAHNNLMAMAQETGDNLYW 1230
                      A  G  G+H    A+ AYA +L         +  N+L   A +  + ++W
Sbjct: 1131 LFCLESAWNVAKEGTHGSHVYTKALLAYAFSLLGKQNQNREIL-NSLDKEAVKEDNLVHW 1189

Query: 1231 GSVTGSQSNAVSPTPAPRNPSDPM-----PQAPALWIETTAYALLHLLLHE-----GKAE 1280
                            P+ P  P+      QAP+  +E T+Y LL  L  +     G   
Sbjct: 1190 --------------ERPQRPKAPVGHLYQTQAPSAEVEMTSYVLLAYLTAQPAPTSGDLT 1235

Query: 1281 MADQAAAWLTRQGSFQGGFRSTQDTVIALDALSAYWIASHTTEERGLNVTLSSTGRNGFK 1340
             A     W+ +Q + QGGF STQDTV+AL ALS Y  A+ T  E+   VT+  +    F 
Sbjct: 1236 SATNIVKWIMKQQNAQGGFSSTQDTVVALHALSRYGAATFTRTEKTAQVTVQDS--QTFS 1293

Query: 1341 SHALQLNNRQIRGLEEELQFSLGSKINVKVGGNSKGTLKVLRTYNVLDMKNTTCQDLQIE 1400
            ++  Q++N  +  L++     L  +  + V G     L+    YN+              
Sbjct: 1294 TN-FQVDNNNLLLLQQISLPELPGEYVITVTGERCVYLQTSMKYNI-------------- 1338

Query: 1401 VTVKGHVEYTMEANEDYEDYEYDELPAKDDPDAPLQPVTPLQLFEGRRNRRRREAPKVVE 1460
                                    LP K+D    L+  T  Q  +G +            
Sbjct: 1339 ------------------------LPEKEDSPFALKVQTVPQTCDGHK------------ 1362

Query: 1461 EQESRVHYTVCIWRNGKVGLSGMAIADVTLLSGFHALRADLEKLTSLSDRYVSHFETEGP 1520
               +    ++ I   G    S M I DV ++SGF  L+  ++ L   S   VS  E    
Sbjct: 1363 -AHTSFQISLTISYTGNRPASNMVIVDVKMVSGFIPLKPTVKMLERSSS--VSRTEVSNN 1419

Query: 1521 HVLLYFDSVPTSRECVGFEAVQEVPVGLVQPASATLYDYYNPERRCSVFYGAP 1573
            HVL+Y + V        F  +Q++PVG ++PA   +YDYY  +      Y AP
Sbjct: 1420 HVLIYVEQVTNQTLSFSFMVLQDIPVGDLKPAIVKVYDYYETDESVVAEYIAP 1472



 Score = 83.2 bits (204), Expect = 2e-15
 Identities = 152/661 (22%), Positives = 263/661 (39%), Gaps = 95/661 (14%)

Query: 20  KPRLLLFSPSVVHLGVPLSVGVQLQDVPRGQVVKGSVFLRNPSRNNVPCSPKVDFT-LSS 78
           +P+ ++  PS++H   P    V L  +     V  S+     +R+         FT L +
Sbjct: 27  EPQYMVLVPSLLHTEAPKKGCVLLSHLNETVTVSASLESGRENRSL--------FTDLVA 78

Query: 79  ERD-FALLSLQVPLKDAKS--CGLHQLLRGPEVQLVAHSPWLKDSLSRTTNIQGINLLFS 135
           E+D F  +S  +P   A S    L   ++GP           +D   R T      +L  
Sbjct: 79  EKDLFHCVSFTLPRISASSEVAFLSIQIKGPT----------QDFRKRNT------VLVL 122

Query: 136 SRRGHLFLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTI-TVMVENSHGLRVRK-KEVYM 193
           + +  +F+QTD+P+Y PGQ VR+RV ++D+  RP  + I  + +EN    R+ + + + +
Sbjct: 123 NTQSLVFVQTDKPMYKPGQTVRFRVVSVDENFRPRNELIPLIYLENPRRNRIAQWQSLKL 182

Query: 194 PSSIFQDDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKITPGKPYIL 253
            + I Q  F +      G++++  +   G        F V+++VLP FEVK+    P I+
Sbjct: 183 EAGINQLSFPLSSEPIQGSYRVVVQTESG--GRIQHPFTVEEFVLPKFEVKVQ--VPKII 238

Query: 254 TVPGHLDEMQLDIQARYIYGKPVQGVAYVRF-----GLLDEDGKKTFFRGLESQTKLVNG 308
           ++    +++ + +   Y YGKPV G+A V        +L+ D ++      E  ++ +N 
Sbjct: 239 SIMD--EKVNITVCGEYTYGKPVPGLATVSLCRKLSRVLNCDKQEV----CEEFSQQLN- 291

Query: 309 QSHISLSKAEFQDALEKLNMGITDLQGLRLYVAAAIIEYPGGEMEEAELTSWYFVSSPFS 368
            S+  +++      L+  N G      ++L V A I E  G ++E          +    
Sbjct: 292 -SNGCITQQVHTKMLQITNTGFE----MKLRVEARIRE-EGTDLEVTANRISEITNIVSK 345

Query: 369 LDLSKTKRHLVPGAPFLLQALVREMSGSPASGIPVKVSATVSSPGSVPEVQDIQQNTDGS 428
           L   K   H   G PF  Q L+ +       G+P+       S        +   N  G 
Sbjct: 346 LKFVKVDSHFRQGIPFFAQVLLVD-----GKGVPIPNKLFFISVNDANYYSNATTNEQGL 400

Query: 429 GQVSIPIIIPQTISELQLSVSAGSPHPAI-------------ARLTVAAPPSGGPGFLSI 475
            Q SI      +IS  +L V   + HP +             A+ T     S    ++ +
Sbjct: 401 AQFSIN---TTSISVNKLFVRVFTVHPNLCFHYSWVAEDHQGAQHTANRVFSLSGSYIHL 457

Query: 476 E-----WPDSRPPRVGDTLNLNLRAVGSGATFSHYYYMILSRGQIVFMNREPKRTLT--- 527
           E      P      +     LN +A+G  +  S ++Y+I+++G IV   R    TL    
Sbjct: 458 EPVAGTLPCGHTETITAHYTLNRQAMGELSELS-FHYLIMAKGVIV---RSGTHTLPVES 513

Query: 528 -------SVSVFVDHHLAPSFYFVAFYYHGDHPVANSLRVDVQAGACEGKLELSVDGAKQ 580
                  ++S  V+  +AP      F    D  V               K++LS   A Q
Sbjct: 514 GDMKGSFALSFPVESDVAPIARMFIFAILPDGEVVGDSEKFEIENCLANKVDLSFSPA-Q 572

Query: 581 YRNGESVKLHLETDSLALVALGALDTALYAAGSKSHKPLNMGKVFEAMNSYDLGCGPGGG 640
                   L +     +L AL A+D ++     K    L++  V+  +   DL   P   
Sbjct: 573 SPPASHAHLQVAAAPQSLCALRAVDQSVLL--MKPEAELSVSSVYNLLTVKDLTNFPDNV 630

Query: 641 D 641
           D
Sbjct: 631 D 631


>gi|118600977 C3 and PZP-like, alpha-2-macroglobulin domain containing
            8 [Homo sapiens]
          Length = 1932

 Score =  235 bits (600), Expect = 2e-61
 Identities = 209/634 (32%), Positives = 296/634 (46%), Gaps = 69/634 (10%)

Query: 969  IPDGDFNSYVRVTASDPLDTLGSEGALSPGGVASLLRLPRGCGEQTMIYLAPTLAASRYL 1028
            +P G      R TAS   D +G     +   + +LLRLP GCGEQ MI+ AP +   +YL
Sbjct: 1154 VPHGAIPGSERATASIIGDVMGP----TLNHLNNLLRLPFGCGEQNMIHFAPNVFVLKYL 1209

Query: 1029 DKTEQWSTLPPETKDHAVDLIQKGYMRIQQFRKADGSYAAWLSRDSS--TWLTAFVLKVL 1086
             KT+Q   L PE +    D + +GY R   +++ DGSY+A+  RD+S   WLTAFVLK  
Sbjct: 1210 QKTQQ---LSPEVERETTDYLVQGYQRQLTYKRQDGSYSAFGERDASGSMWLTAFVLKSF 1266

Query: 1087 SLAQEQVGGSPEKLQETSNWLLSQQQADGSFQDPCPVLDRSMQGGLVGNDETVALTAFVT 1146
            + A+  +   P +L    +W++ QQQADGSF     VL++ +QGG+ G   TV LTA+V 
Sbjct: 1267 AQARSFIFVDPRELAAAKSWIIQQQQADGSFLAVGRVLNKDIQGGIHG---TVPLTAYVV 1323

Query: 1147 IA-LHHGLAVFQDEGAEPLKQRVEASISKANSFLGEKASAGLLGAHAAAITAYALTLTKA 1205
            +A L  G A  ++ G          S  KA  FL E A+   +  ++ A+T YALTL ++
Sbjct: 1324 VALLETGTASEEERG----------STDKARHFL-ESAAPLAMDPYSCALTTYALTLLRS 1372

Query: 1206 PVDLLGVAHNNLMAMAQETGDNLYWGSVTGSQSNAVSPTPAP-RNPSDPMPQA-PALWIE 1263
            P      A   L ++A       +W     S SN+         + SD + Q+  +  +E
Sbjct: 1373 PA--APEALRKLRSLAIMRDGVTHW-----SLSNSWDVDKGTFLSFSDRVSQSVVSAEVE 1425

Query: 1264 TTAYALLHLLLHEGKAEMADQAAAWLTRQGSFQGGFRSTQDTVIALDALSAYWIASHTTE 1323
             TAYALL   L  G    A     WL++Q +  GGF STQDT +AL AL+ Y I S+   
Sbjct: 1426 MTAYALLTYTL-LGDVAAALPVVKWLSQQRNALGGFSSTQDTCVALQALAEYAILSYA-- 1482

Query: 1324 ERGLNVTLSSTGRNGFKSHALQLNNRQIRGLEEELQFSLGSKINVKVGGNSKGTLKVLRT 1383
              G+N+T+S    N       +L+    + L+     SL + + V   G+    +++  T
Sbjct: 1483 -GGINLTVSLASTNLDYQETFELHRTNQKVLQTAAIPSLPTGLFVSAKGDGCCLMQIDVT 1541

Query: 1384 YNVLDMKNTTCQDLQI---EVTVKGHVEYTMEANEDYEDYEYDELPAKDDPDAPLQPVTP 1440
            YNV D        L +   E   +G     M A+   E    D  PA DD  A  Q    
Sbjct: 1542 YNVPDPVAKPAFQLLVSLQEPEAQGRPP-PMPASA-AEGSRGDWPPADDDDPAADQ---- 1595

Query: 1441 LQLFEGRRNRRRREAPKVVEEQESRVHYTVCI-WRNGKVGLSGMAIADVTLLSGFHALRA 1499
                                 QE +V   VC  W +   G S MA+ +V LLSGF A   
Sbjct: 1596 -------------------HHQEYKVMLEVCTRWLH--AGSSNMAVLEVPLLSGFRADIE 1634

Query: 1500 DLEKLTSLSDRYVSHFETEGPHVLLYFDSVPT-SRECVGFEAVQEVPVGLVQPASATLYD 1558
             LE+L       +  +E  G  VL YFD +P+    CV F A++E  VG       ++YD
Sbjct: 1635 SLEQLLLDKHMGMKRYEVAGRRVLFYFDEIPSRCLTCVRFRALRECVVGRTSALPVSVYD 1694

Query: 1559 YYNPERRCSVFYGAPSKSRLLATLCSAEVCQCAE 1592
            YY P    + FY   + S L   LC+   C   E
Sbjct: 1695 YYEPAFEATRFYNVSTHSPLARELCAGPACNEVE 1728



 Score = 93.6 bits (231), Expect = 2e-18
 Identities = 152/711 (21%), Positives = 274/711 (38%), Gaps = 128/711 (18%)

Query: 19  QKPRLLLFSPSVVHLGVPLSVGVQLQDVPRGQVVKGSVFLRNPSRNNVPCSPKVDFTLSS 78
           Q P  L+ +PSV   GV   + V + + PR   V+  +  +          P V  +  +
Sbjct: 76  QAPGYLIAAPSVFRAGVEEVISVTIFNSPREVTVQAQLVAQG--------EPVVQ-SQGA 126

Query: 79  ERDFALLSLQVPLKDAKSCGLHQLLRGPEVQLVAHSPWLKDSLSRTTNIQGINLLFSSRR 138
             D   + L+VP            LRG  +  V    W  +      N   + +    R 
Sbjct: 127 ILDKGTIKLKVPTG----------LRGQALLKVWGRGWQAEEGPLFHNQTSVTV--DGRG 174

Query: 139 GHLFLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTITVMVENSHGLRVRKKEVYMP--SS 196
             +F+QTD+P+Y P  RV   +F +   +RP  + +   + +  G R+ +     P    
Sbjct: 175 ASVFIQTDKPVYRPQHRVLISIFTVSPNLRPVNEKLEAYILDPRGSRMIEWRHLKPFCCG 234

Query: 197 IFQDDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKITPGKPYILTVP 256
           I    F + D    G W I         + S   FEV+KYVLP FE+ I P        P
Sbjct: 235 ITNMSFPLSDQPVLGEWFIFVEMQGHAYNKS---FEVQKYVLPKFELLIDP--------P 283

Query: 257 GHLDEMQL----DIQARYIYGKPVQGVAYVRF-----GLLDEDGKKTFFRGLESQTKLVN 307
            ++ ++       ++ARY +GKPV G   +       G    +  +   R     TK+  
Sbjct: 284 RYIQDLDACETGTVRARYTFGKPVAGALMINMTVNGVGYYSHEVGRPVLR----TTKI-- 337

Query: 308 GQSHISLSKAEFQDAL-EKLNMGITDLQGLRLYVAAAIIEYPGGE---MEEAELTSWYFV 363
                 L   +F   + + +   + +    R+ + A +    G +    +++       V
Sbjct: 338 ------LGSRDFDICVRDMIPADVPEHFRGRVSIWAMVTSVDGSQQVAFDDSTPVQRQLV 391

Query: 364 SSPFSLDLSKTKRHLVPGAPFLLQALVREMSGSPASGIPVKVSATVSSPGSVPEVQDI-Q 422
              +S D   T++   PG  ++ +  +    GSPA G+ V++ A ++   ++   + + Q
Sbjct: 392 DIRYSKD---TRKQFKPGLAYVGKVELSYPDGSPAEGVTVQIKAELTPKDNIYTSEVVSQ 448

Query: 423 QNTDGSGQVSIPIIIPQTISELQLSVSAGSPHPA---IARLTVAAPPSGGPGFLSIEWPD 479
           +   G    SIP        E ++    G P  A    + L++ +  S    +L ++ P 
Sbjct: 449 RGLVGFEIPSIPTSAQHVWLETKVMALNGKPVGAQYLPSYLSLGSWYSPSQCYLQLQ-PP 507

Query: 480 SRPPRVGDTLNLNLRAVGSGATFSHYYYMILSRGQIVFMNREPKRT-------------- 525
           S P +VG+    ++++      F+  YY + +RG IV   ++P  T              
Sbjct: 508 SHPLQVGEEAYFSVKST-CPCNFT-LYYEVAARGNIVLSGQQPAHTTQQRSKRAAPALEK 565

Query: 526 -----------------------LTSVSVFVDHHLAPSFYFVAFYY-HGDHPVANSLRVD 561
                                  +TS+ + V   + P    + FY       VA+SL+  
Sbjct: 566 PIRLTHLSETEPPPAPEAEVDVCVTSLHLAVTPSMVPLGRLLVFYVRENGEGVADSLQFA 625

Query: 562 VQAGACEGKLELSVDGAKQYRNGESVKLHLETDSLALVALGALDTALYAAGSKSHKPLNM 621
           V+    E ++ ++   A + + GE V L +     + V + A+D ++Y    +S   L  
Sbjct: 626 VET-FFENQVSVTY-SANETQPGEVVDLRIRAARGSCVCVAAVDKSVYLL--RSGFRLTP 681

Query: 622 GKVFEAMNSYDLGCGPGGGDSALQVFQAAGLAFSDGDQW----TLSRKRLS 668
            +VF+ +  YD             V  + G++  DG  W    T  R+R S
Sbjct: 682 AQVFQELEDYD-------------VSDSFGVSREDGPFWWAGLTAQRRRRS 719



 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 39/129 (30%), Positives = 70/129 (54%), Gaps = 6/129 (4%)

Query: 775 RSFFPENWLWRVETVDRFQ---ILTLWLPDSLTTWEIHGLSLSKTKGLCVATPVQLRVFR 831
           R+FFPE W+W    +        L++ +PDS+T+W    ++LS ++GL +A P  L+ F+
Sbjct: 791 RTFFPETWIWHCLNISDPSGEGTLSVKVPDSITSWVGEAVALSTSQGLGIAEPSLLKTFK 850

Query: 832 EFHLHLRLPMSVRRFEQLELRPVLYNYLDKNLTVSVHVSPVEGLCLAGGGG---LAQQVL 888
            F +   LP  + R EQ+++   +YNY+     V + +S  +G+   G  G   + +++ 
Sbjct: 851 PFFVDFMLPALIIRGEQVKIPLSVYNYMGTCAEVYMKLSVPKGIQFVGHPGKRHVTKKMC 910

Query: 889 VPAGSARPV 897
           V  G A P+
Sbjct: 911 VAPGEAEPI 919


>gi|74271845 alpha-2-macroglobulin-like 1 [Homo sapiens]
          Length = 1454

 Score =  216 bits (549), Expect = 2e-55
 Identities = 207/829 (24%), Positives = 356/829 (42%), Gaps = 126/829 (15%)

Query: 770  DDIPVRSFFPENWLWRVETVDRF--QILTLWLPDSLTTWEIHGLSLSKTKGLCVATPVQL 827
            +D  VR +FPE WLW +  +     + + + +PD++T W+      S+++G  ++  V L
Sbjct: 725  EDSQVRQYFPETWLWDLFPIGNSGKEAVHVTVPDAITEWKAMSFCTSQSRGFGLSPTVGL 784

Query: 828  RVFREFHLHLRLPMSVRRFEQLELRPVLYNYLDKNLTVSVHVSPVEGLCLAGGGGLAQQV 887
              F+ F + L LP SV R E   L   ++NYL   + V   ++      L          
Sbjct: 785  TAFKPFFVDLTLPYSVVRGESFRLTATIFNYLKDCIRVQTDLAKSHEYQLESWADSQTSS 844

Query: 888  LVPAGSARPVAFSVVPTAAAAVSLKVVAR--GSFEFPVG------------DAVSKVLQI 933
             + A  A+   +++       ++  +  +   S E P G            D + K + +
Sbjct: 845  CLCADEAKTHHWNITAVKLGHINFTISTKILDSNE-PCGGQKGFVPQKGRSDTLIKPVLV 903

Query: 934  EKEGAIHRE---ELVYELNPLDHRGRTLEIPGNSDPNMIPDGDFNSYVRVTASDPLDTLG 990
            + EG +  +    L+     +     +LE+P     +++PD    +YV V      D +G
Sbjct: 904  KPEGVLVEKTHSSLLCPKGKVASESVSLELP----VDIVPDST-KAYVTVLG----DIMG 954

Query: 991  SEGALSPGGVASLLRLPRGCGEQTMIYLAPTLAASRYLDKTEQWSTLPPETKDHAVDLIQ 1050
            +  AL    +  L+++P GCGEQ M+  AP +   +YL+K      L  E +  AV  ++
Sbjct: 955  T--ALQ--NLDGLVQMPSGCGEQNMVLFAPIIYVLQYLEKA---GLLTEEIRSRAVGFLE 1007

Query: 1051 KGYMRIQQFRKADGSYAAWLSRDSS--TWLTAFVLKVLSLAQEQVGGSPEKLQETSNWLL 1108
             GY +   ++ ++GSY+A+  RD +  TWLTAFV K    AQ+ +   P+ +Q+   W+ 
Sbjct: 1008 IGYQKELMYKHSNGSYSAFGERDGNGNTWLTAFVTKCFGQAQKFIFIDPKNIQDALKWMA 1067

Query: 1109 SQQQADGSFQDPCPVLDRSMQGGLVGNDETVALTAFVTIALHHGLAVFQDEGAEPLKQRV 1168
              Q   G + +   +L  +M+GG+   D+ V+LTA+VT AL   L + +D     + Q +
Sbjct: 1068 GNQLPSGCYANVGNLLHTAMKGGV---DDEVSLTAYVTAAL---LEMGKDVDDPMVSQGL 1121

Query: 1169 EASISKANSFLGEKASAGLLGAHAAAITAYALTLTKAPVDLLGVAHNNLMAMAQETGDNL 1228
                + A S             +  A+ AY  +L    +D+  +    L   A  +G+++
Sbjct: 1122 RCLKNSATS---------TTNLYTQALLAYIFSLA-GEMDIRNILLKQLDQQAIISGESI 1171

Query: 1229 YWGSVTGSQSNAVSPTPAPRNPSDPMPQAPALWIETTAYALLHLL----LHEGKAEMADQ 1284
            YW           S  P P + + P  +  A+ +E TAYALL  L    L + +   A  
Sbjct: 1172 YW-----------SQKPTPSSNASPWSEPAAVDVELTAYALLAQLTKPSLTQKEIAKATS 1220

Query: 1285 AAAWLTRQGSFQGGFRSTQDTVIALDALSAYWIASHTTEERGLNVTLSSTGRNGFKSHAL 1344
              AWL +Q +  GGF STQDTV+AL AL+ Y   ++   E  +N+ + ST  N  ++  +
Sbjct: 1221 IVAWLAKQRNAYGGFSSTQDTVVALQALAKYATTAYMPSEE-INLVVKST-ENFQRTFNI 1278

Query: 1345 QLNNRQIRGLEEELQFSLGSKINVKVGGNSKGTLKVLRTYNVLDMKNTTCQDLQIEVTVK 1404
            Q  NR +   +++   ++     ++  G     ++ +  YN+L   N     L +E+  K
Sbjct: 1279 QSVNRLV--FQQDTLPNVPGMYTLEASGQGCVYVQTVLRYNILPPTNMKTFSLSVEIG-K 1335

Query: 1405 GHVEYTMEANEDYEDYEYDELPAKDDPDAPLQPVTPLQLFEGRRNRRRREAPKVVEEQES 1464
               E                           QP +P  L                     
Sbjct: 1336 ARCE---------------------------QPTSPRSL--------------------- 1347

Query: 1465 RVHYTVCIWRNGKVGLSGMAIADVTLLSGFHALRADLEKLTSLSDRYVSHFETEGPHVLL 1524
                T+     G    S MAI +V +LSGF  +    + L  L    V   E     + +
Sbjct: 1348 --TLTIHTSYVGSRSSSNMAIVEVKMLSGFSPMEGTNQLL--LQQPLVKKVEFGTDTLNI 1403

Query: 1525 YFDSVPTSRECVGFEAVQEVPVGLVQPASATLYDYYNPERRCSVFYGAP 1573
            Y D +  + +   F   Q V V  ++PA+  +YDYY P+ + ++ Y  P
Sbjct: 1404 YLDELIKNTQTYTFTISQSVLVTNLKPATIKVYDYYLPDEQATIQYSDP 1452



 Score = 62.4 bits (150), Expect = 4e-09
 Identities = 65/257 (25%), Positives = 116/257 (45%), Gaps = 22/257 (8%)

Query: 142 FLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTIT-VMVENSHGLRVRK-KEVYMPSSIFQ 199
           F+QTD+P+Y PGQ+V +R+  +D    P  D  + V +++ +  R+ +  EV     I  
Sbjct: 123 FVQTDKPLYTPGQQVYFRIVTMDSNFVPVNDKYSMVELQDPNSNRIAQWLEVVPEQGIVD 182

Query: 200 DDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKITPGKPYILTVPGHL 259
             F +   +  GT+ ++       E  +   F V++YVLP F+V++   K  + TV    
Sbjct: 183 LSFQLAPEAMLGTYTVAV-----AEGKTFGTFSVEEYVLPKFKVEVVEPKE-LSTVQ--- 233

Query: 260 DEMQLDIQARYIYGKPVQGVAYVRFGLLDEDGKKTFFRGLESQTKLVNGQSHISLSKAEF 319
           +   + I  RY YGKP+ G   V    + +     ++R +E + +L +   ++S    + 
Sbjct: 234 ESFLVKICCRYTYGKPMLGAVQVS---VCQKANTYWYREVERE-QLPDKCRNLSGQTDKT 289

Query: 320 QDALEKLNMGITDLQGL----RLYVAAAIIEYPGGEMEEAELTSWYFVSSPF-SLDLSKT 374
                 ++M   DL G     ++ + A ++E   G   EA  T   ++S    S+    T
Sbjct: 290 GCFSAPVDMATFDLIGYAYSHQINIVATVVE--EGTGVEANATQNIYISPQMGSMTFEDT 347

Query: 375 KRHLVPGAPFLLQALVR 391
                P  PF  +  VR
Sbjct: 348 SNFYHPNFPFSGKIRVR 364


>gi|227430301 CD109 antigen isoform 2 precursor [Homo sapiens]
          Length = 1428

 Score =  208 bits (529), Expect = 4e-53
 Identities = 175/574 (30%), Positives = 268/574 (46%), Gaps = 64/574 (11%)

Query: 774  VRSFFPENWLWRVETVDR--FQILTLWLPDSLTTWEIHGLSLSKTKGL-CVATPVQLRVF 830
            VR  FPE W+W    +    +Q   + +PDS+T+W   G  +S+  GL    TPV+L+ F
Sbjct: 686  VRKHFPETWIWLDTNMGYRIYQEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVELQAF 745

Query: 831  REFHLHLRLPMSVRRFEQLELRPVLYNYLDKNLTVSVHVSPVEGLCLA------GGGGLA 884
            + F + L LP SV R E+  L   ++NYL     V V +   +   +          G  
Sbjct: 746  QPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEVKVIIEKSDKFDILMTSNEINATGHQ 805

Query: 885  QQVLVPAGSARPVAFSVVPTAAAAVSLKVVARGSFEFPVGDAVSKVLQIEKEGA--IHRE 942
            Q +LVP+     V F + PT    + + V A         DAV++++ ++ EG    + +
Sbjct: 806  QTLLVPSEDGATVLFPIRPTHLGEIPITVTALSP---TASDAVTQMILVKAEGIEKSYSQ 862

Query: 943  ELVYEL--NPLDHRGRTLEIPGNSDPNMIPDGDFNSYVRVTASDPLDTLGSEGALSPGGV 1000
             ++ +L  N L    +TL    +  PN +   +    V++TA    D LG     S  G+
Sbjct: 863  SILLDLTDNRLQSTLKTLSF--SFPPNTVTGSE---RVQITAIG--DVLGP----SINGL 911

Query: 1001 ASLLRLPRGCGEQTMIYLAPTLAASRYLDKTEQWSTLPPETKDHAVDLIQKGYMRIQQFR 1060
            ASL+R+P GCGEQ MI  AP +    YL K +Q   L    K+ A+  +++GY R   ++
Sbjct: 912  ASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQ---LTDNLKEKALSFMRQGYQRELLYQ 968

Query: 1061 KADGSYAAWLSRD--SSTWLTAFVLKVLSLAQEQVGGSPEKLQETSNWLLSQQQADGSFQ 1118
            + DGS++A+ + D   STWL+AFVL+    A   +      L  T  WL   Q+++G F 
Sbjct: 969  REDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDIDQNVLHRTYTWLKGHQKSNGEFW 1028

Query: 1119 DPCPVLDRSMQGGLVGNDETVALTAFVTIALHHGLAVFQDEGAEPLKQRVEASISKANSF 1178
            DP  V+   +QG   GN   V LTA++  +L               K +    + ++  F
Sbjct: 1029 DPGRVIHSELQG---GNKSPVTLTAYIVTSL-----------LGYRKYQPNIDVQESIHF 1074

Query: 1179 LGEKASAGLLGAHAAAITAYALTLTKAPVDLLGVAHNNLMAMAQETGDNLYWGSVTGSQS 1238
            L  + S G+   +  A+  YAL+   +P      A N L   A++ G   +W S     S
Sbjct: 1075 LESEFSRGISDNYTLALITYALSSVGSP--KAKEALNMLTWRAEQEGGMQFWVSSESKLS 1132

Query: 1239 NAVSPTPAPRNPSDPMPQAPALWIETTAYALLHLLLHEGKAEMADQAAAWLTRQGSFQGG 1298
            ++  P               +L IE  AYALL   L    +E       WL+RQ +  GG
Sbjct: 1133 DSWQPR--------------SLDIEVAAYALLSHFLQFQTSE-GIPIMRWLSRQRNSLGG 1177

Query: 1299 FRSTQDTVIALDALSAYWIASHTTEERGLNVTLS 1332
            F STQDT +AL ALS +  A   TE   + VT++
Sbjct: 1178 FASTQDTTVALKALSEF-AALMNTERTNIQVTVT 1210



 Score =  100 bits (250), Expect = 9e-21
 Identities = 146/656 (22%), Positives = 270/656 (41%), Gaps = 67/656 (10%)

Query: 21  PRLLLFSPSVVHLGVPLSVGVQLQDVPRGQVVKGSVFLRNPSRNNVPCSPKVDFTLSSER 80
           PR L+ +P ++  G  +++GV+L +    QV   +  L+  S  N+  S      +  + 
Sbjct: 26  PRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKAELLKTAS--NLTVSVLEAEGVFEKG 83

Query: 81  DFALLSL-QVPLKDAKSCGLHQLLRGPEVQLVAHSPWLKDSLSRTTNIQGINLLFSSRRG 139
            F  L+L  +PL  A            E+  +  +   +D +  + + +   L F ++R 
Sbjct: 84  SFKTLTLPSLPLNSAD-----------EIYELRVTGRTQDEILFSNSTR---LSFETKRI 129

Query: 140 HLFLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTITVMVENSHGLRVRK-KEVYMPSSIF 198
            +F+QTD+ +Y P Q V++R+  L    +P   ++ +++++     +++         + 
Sbjct: 130 SVFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNILIKDPKSNLIQQWLSQQSDLGVI 189

Query: 199 QDDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKI-TPGKPYILTVPG 257
              F +      G W I  + +D     S   F+V +YVLP FEV + TP   Y      
Sbjct: 190 SKTFQLSSHPILGDWSIQVQVNDQTYYQS---FQVSEYVLPKFEVTLQTP--LYCSMNSK 244

Query: 258 HLDEMQLDIQARYIYGKPVQGVAYVRFGLLDEDGKKTFFRGLESQTKLVNGQSHISLSKA 317
           HL+     I A+Y YGKPV+G   + F  L   GKK       ++T  +NG ++ S +  
Sbjct: 245 HLNG---TITAKYTYGKPVKGDVTLTFLPLSFWGKKKNI----TKTFKINGSANFSFNDE 297

Query: 318 EFQDALEKLNMGITDLQGLR----LYVAAAIIEYPGGEMEEAELTSWYFVSSPFSLDLSK 373
           E ++ ++  N G+++   L     + +   + E   G       T+ +F    + ++   
Sbjct: 298 EMKNVMDSSN-GLSEYLDLSSPGPVEILTTVTESVTGISRNVS-TNVFFKQHDYIIEFFD 355

Query: 374 TKRHLVPGAPFLLQALVREMSGSP------ASGIPVKV---------SATVSSPGSVPEV 418
               L P   F     V    G+        + + + V         S + S    +  V
Sbjct: 356 YTTVLKPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAV 415

Query: 419 QDIQQNTDGSGQVSIPIIIPQTISELQLSVSAGSPHPAIARLTVAAPPSGGPGFLSIEWP 478
           Q I      SG   I   I +  SELQL         ++A  ++   PS    ++ ++  
Sbjct: 416 QKINYTVPQSGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFKSPS--KTYIQLKTR 473

Query: 479 DSRPPRVGDTLNLNLRAVGSGATFSHYYYMILSRGQIVFMNREPKRTLTSVSVFVDHHLA 538
           D    +VG    L    V          YM++SRGQ+V +    K+  T  S+  ++   
Sbjct: 474 DEN-IKVGSPFEL---VVSGNKRLKELSYMVVSRGQLVAVG---KQNSTMFSLTPENSWT 526

Query: 539 PSFYFVAFYYHGD-HPVANSLRVDVQAGACEGKLELSVDGAKQYRNGESVKLHLE-TDSL 596
           P    + +Y   D   +++ L++ VQ    + K++L     K     E V L +  T   
Sbjct: 527 PKACVIVYYIEDDGEIISDVLKIPVQL-VFKNKIKLYWSKVKA-EPSEKVSLRISVTQPD 584

Query: 597 ALVALGALDTALYAAGSKSHKPLNMGKVFEAMNSYDLGCGPGGGDSALQVFQAAGL 652
           ++V + A+D ++    + +   + M  V   +  Y+ G   G   ++  VFQ  GL
Sbjct: 585 SIVGIVAVDKSVNLMNASN--DITMENVVHELELYNTGYYLGMFMNSFAVFQECGL 638



 Score = 57.8 bits (138), Expect = 9e-08
 Identities = 47/142 (33%), Positives = 67/142 (47%), Gaps = 12/142 (8%)

Query: 1455 APKVVEEQESRVHYTVCIWRNGKVGLSGMAIADVTLLSGFHALRADLEKLTSLSDRYVSH 1514
            A K  ++  + V   VC   +G  G SGMA+ +V LLSGF        +  SLS+  V  
Sbjct: 1269 AVKENKDDLNHVDLNVCTSFSGP-GRSGMALMEVNLLSGFMVP----SEAISLSET-VKK 1322

Query: 1515 FETEGPHVLLYFDSVPTSRECVGFEAVQEVPVGLVQPASATLYDYYNPERRCSVFYGAPS 1574
             E +   + LY DSV  ++ CV   AV+   V   Q AS ++ DYY P R+    Y +  
Sbjct: 1323 VEYDHGKLNLYLDSVNETQFCVNIPAVRNFKVSNTQDASVSIVDYYEPRRQAVRSYNSEV 1382

Query: 1575 KSRLLATLCSAEVCQCAEGKCP 1596
            K      L S ++C   +G  P
Sbjct: 1383 K------LSSCDLCSDVQGCRP 1398


>gi|239744583 PREDICTED: ovostatin 2 [Homo sapiens]
          Length = 1394

 Score =  135 bits (341), Expect = 3e-31
 Identities = 159/649 (24%), Positives = 264/649 (40%), Gaps = 68/649 (10%)

Query: 774  VRSFFPENWLWRVETVDRFQI--LTLWLPDSLTTWEIHGLSLSKTKGLCVATPVQLRVFR 831
            VR+ FPE W+W + +VD      L+  +PD++T WE  G  ++   G  +++   L V +
Sbjct: 719  VRTNFPETWMWDLVSVDSSGSANLSFLIPDTITQWEASGFCVNGDVGFGISSTTTLEVSQ 778

Query: 832  EFHLHLRLPMSVRRFEQLELRPVLYNYLDKNLTVSVHVSPVEGL-CLAGGGGLAQQVLVP 890
             F + +  P SV + EQ +L    ++YL+  + +SV V   +          +    ++ 
Sbjct: 779  PFFIEIASPFSVVQNEQFDLIVNAFSYLNTCVEISVQVEESQNYEANINTWKINGSEVIQ 838

Query: 891  AGSARPVAFSVVPTAAAAVSLKVVARG------------SFEFPVGDAVSKVLQIEKEGA 938
            AG  +   ++++P     V++ VVA                +    D V K   +E EG 
Sbjct: 839  AGGRKTNIWTIIPKKLGKVNITVVAESKQSSACPNEGMEQQKLNWKDTVVKSFLVEPEG- 897

Query: 939  IHREELVYELNPLDHRGRTLEIPGNSD-PNMIPDGDFNSYVRVTASDPLDTLGSEGALSP 997
            I +E     L  +   G      G  D PN + +G    +  V      D LG    L+ 
Sbjct: 898  IEKERTQSFL--ICTEGAKASKQGVLDLPNDVVEGSARGFFTVVG----DILG----LAM 947

Query: 998  GGVASLLRLPRGCGEQTMIYLAPTLAASRYLDKTEQWSTLPPETKDHAVDLIQKGYMRIQ 1057
              +  +L++P G GEQ    LA       YL  TEQ   L  E +  A  L+  GY R  
Sbjct: 948  QNLV-VLQMPYGGGEQNAALLASDTYVLDYLKSTEQ---LTEEVQSKAFFLLSNGYQRQL 1003

Query: 1058 QFRKADGSYAAWLSRD--SSTWLTAFVLKVLSLAQEQVGGSPEKLQETSNWLLSQQQADG 1115
             F+ +DGSY+ +  ++   S WL+A   K L   ++ V       ++T  WL SQQ+  G
Sbjct: 1004 SFKNSDGSYSVFWQQNQKGSIWLSALTFKTLERMKKFVFIDENVQKQTLIWLSSQQKTSG 1063

Query: 1116 SFQDPCPVLDRSMQGGLVGNDETVALTAFVTIALHHGLAVFQDEGAEPLKQRVEASISKA 1175
             F++   + + + +G   G++E ++LTA+V       + +F + G          ++  A
Sbjct: 1064 CFKNDGQLFNHAWEG---GDEEDISLTAYV-------VGMFFEAGL----NSTFPALRNA 1109

Query: 1176 NSFLGEKASAGLLGAHAAAITAYALTLTKAPVDLLGVAHNNLMAMAQETGDNLYWGSVTG 1235
               L     +G+   +  AI AYA  L      +  +    L   A +  + +YW     
Sbjct: 1110 LFCLEAALDSGVTNGYNHAILAYAFALAGKEKQVESLL-QTLDQSATKLNNVIYW----- 1163

Query: 1236 SQSNAVSPTPAPRNPSDP--MPQAPALWIETTAYALLHLLLHE-GKAEMADQAAAWLTRQ 1292
                       P+    P  +P AP+   E + Y LL ++  +      A +   WL +Q
Sbjct: 1164 ------ERERKPKTEEFPSFIPWAPSAQTEKSCYVLLAVISRKIPDLTYASKIVQWLAQQ 1217

Query: 1293 GSFQGGFRSTQDTVIALDALSAYWIASHTTEERGLNVTLSSTGRNGFKSHALQLNNRQIR 1352
             +  GGF S Q   + L  L A         +    VT SS G     S  +Q N     
Sbjct: 1218 MNSHGGFSSNQVINVGL-ILIAICGEEGLFSKNQNTVTFSSEG-----SSEIQFNGHNRL 1271

Query: 1353 GLEEELQFSLGSKINVKVGGNSKGTLKVLRTYNVLDMKNTTCQDLQIEV 1401
             ++         +  V V G     ++    YNVL  K  +   L +E+
Sbjct: 1272 LVQRSEVTQAPGQYTVDVEGRGCTFIQATLKYNVLLPKKASGFSLSLEI 1320



 Score = 60.8 bits (146), Expect = 1e-08
 Identities = 55/157 (35%), Positives = 80/157 (50%), Gaps = 24/157 (15%)

Query: 136 SRRGHLFLQTDQPIYNPGQRVRYRV--FALDQKMRPSTDTIT---VMVENSHGLRVRK-K 189
           SR   +F+QTD+P Y PGQ+    +  F LD      T T T   + +++    R+ + +
Sbjct: 105 SRENVVFVQTDKPTYKPGQKDVNGIAQFFLD------TYTFTYPNITLKDPQNNRIFQWQ 158

Query: 190 EVYMPSSIFQDDFVIPDISEP---GTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKIT 246
            V    +I Q  F +  ISEP     W +  R S       + QF VK+YVLP FEV  T
Sbjct: 159 NVTSFRNITQLSFQL--ISEPMFGDYWIVVKRNS---RKTVTHQFAVKRYVLPKFEV--T 211

Query: 247 PGKPYILTVPGHLDEMQLDIQARYIYGKPVQGVAYVR 283
              P  +T+    DE Q+D+ A+Y +G+PVQG   +R
Sbjct: 212 VNAPQTVTISD--DEFQVDVCAKYTFGQPVQGKTQIR 246


>gi|169204289 PREDICTED: ovostatin [Homo sapiens]
          Length = 1353

 Score =  132 bits (331), Expect = 4e-30
 Identities = 160/661 (24%), Positives = 269/661 (40%), Gaps = 84/661 (12%)

Query: 774  VRSFFPENWLWRVETVDRFQI--LTLWLPDSLTTWEIHGLSLSKTKGLCVATPVQLRVFR 831
            VR+ FPE W+W + +VD      L+  +PD++T WE  G  ++   G  +++   L V +
Sbjct: 670  VRTNFPETWMWDLVSVDSSGSANLSFLIPDTITQWEASGFCVNGDVGFGISSTTTLEVSQ 729

Query: 832  EFHLHLRLPMSVRRFEQLELRPVLYNYLDKNLTVSVHV-------SPVEGLCLAGGGGLA 884
             F + +  P SV + EQ +L   +++Y +  + +SV V       + +  L + G     
Sbjct: 730  PFFIEIASPFSVVQNEQFDLIVNVFSYRNTCVEISVQVEESQNYEANIHTLKING----- 784

Query: 885  QQVLVPAGSARPVAFSVVPTAAAAVSLKVVARG------------SFEFPVGDAVSKVLQ 932
               ++ AG  +   ++++P     V++ VVA                +    D V +   
Sbjct: 785  -SEVIQAGGRKTNVWTIIPKKLGKVNITVVAESKQSSACPNEGMEQQKLNWKDTVVQSFL 843

Query: 933  IEKEGAIHREELVYELNPLDHRGRTLEIPGNSD-PNMIPDGDFNSYVRVTASDPLDTLGS 991
            +E EG I +E     L  +   G      G  D PN + +G    +  V      D LG 
Sbjct: 844  VEPEG-IEKERTQSFL--ICTEGAKASKQGVLDLPNDVVEGSARGFFTVVG----DILGL 896

Query: 992  EGALSPGGVASLLRLPRGCGEQTMIYLAPTLAASRYLDKTEQWSTLPPETKDHAVDLIQK 1051
              AL       +L++P G GEQ    LA       YL  TEQ   L  E +  A  L+  
Sbjct: 897  --ALQN---LVVLQMPYGSGEQNAALLASDTYVLDYLKSTEQ---LTEEVQSKAFFLLSN 948

Query: 1052 GYMRIQQFRKADGSYAAW--LSRDSSTWLTAFVLKVLSLAQEQVGGSPEKLQETSNWLLS 1109
            GY R   F+ +DGSY+ +   S+  S  L+A   K L   ++ V       ++T  WL S
Sbjct: 949  GYQRQLSFKNSDGSYSVFWQQSQKGSIXLSALTFKTLERMKKYVFIDENVQKQTLIWLSS 1008

Query: 1110 QQQADGSFQDPCPVLDRSMQGGLVGNDETVALTAFVTIALHHGLAVFQDEGAEPLKQRVE 1169
            QQ+  G F++   + + + +G   G++E ++LTA+V       + +F + G         
Sbjct: 1009 QQKTSGCFKNDGQLFNHAWEG---GDEEDISLTAYV-------VGMFFEAGL----NFTF 1054

Query: 1170 ASISKANSFLGEKASAGLLGAHAAAITAYALTLTKAPVDLLGVAHNNLMAMAQETGDNLY 1229
             ++  A   L     +G+   +  AI AYA  L      +  +    L   A +  + +Y
Sbjct: 1055 PALRNALFCLEAALDSGVTNGYNHAILAYAFALAGKEKQVESLL-QTLDQSAPKLNNVIY 1113

Query: 1230 WGSVTGSQSNAVSPTPAPRNPSDP--MPQAPALWIETTAYALLHLLLHE-GKAEMADQAA 1286
            W                P+    P  +P AP+   E + Y LL ++  +      A +  
Sbjct: 1114 W-----------ERERKPKTEEFPSFIPWAPSAQTEKSCYVLLAVISRKIPDLTYASKIV 1162

Query: 1287 AWLTRQGSFQGGFRSTQDTVIALDALSAYWIASHTTEERGL------NVTLSSTGRNGFK 1340
             WL ++ +  GGF S Q   + L  ++   +      E GL       VT SS G     
Sbjct: 1163 QWLAQRMNSHGGFSSNQVINVGLILIAICLMQKLARGEEGLFSKDQNTVTFSSEG----S 1218

Query: 1341 SHALQLNNRQIRGLEEELQFSLGSKINVKVGGNSKGTLKVLRTYNVLDMKNTTCQDLQIE 1400
            S   Q+N      ++         +  V V G+    ++    YNVL  K  +   L +E
Sbjct: 1219 SEIFQVNGHNRLLVQRSEVTQAPGEYTVDVEGHGCTFIQATLKYNVLLPKKASGFSLSLE 1278

Query: 1401 V 1401
            +
Sbjct: 1279 I 1279



 Score = 62.0 bits (149), Expect = 5e-09
 Identities = 55/157 (35%), Positives = 81/157 (51%), Gaps = 24/157 (15%)

Query: 136 SRRGHLFLQTDQPIYNPGQRVRYRV--FALDQKMRPSTDTIT---VMVENSHGLRV-RKK 189
           SR   +F+QTD+P Y PGQ+    +  F LD      T T T   + +++    R+ +++
Sbjct: 56  SRENVVFVQTDKPTYKPGQKDVNGIAQFFLD------TYTFTYPNITLKDPQNNRIFQRQ 109

Query: 190 EVYMPSSIFQDDFVIPDISEP---GTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKIT 246
            V    +I Q  F +  ISEP     W +  R S       + QF VK+YVLP FEV  T
Sbjct: 110 NVTSFRNITQLSFQL--ISEPMFGDYWIVVKRNS---RETVTHQFAVKRYVLPKFEV--T 162

Query: 247 PGKPYILTVPGHLDEMQLDIQARYIYGKPVQGVAYVR 283
              P  +T+    DE Q+D+ A+Y +G+PVQG   +R
Sbjct: 163 VNAPQTVTISD--DEFQVDVCAKYNFGQPVQGETQIR 197


>gi|169214179 PREDICTED: similar to complement component 3 [Homo
            sapiens]
          Length = 390

 Score =  128 bits (322), Expect = 4e-29
 Identities = 107/444 (24%), Positives = 183/444 (41%), Gaps = 64/444 (14%)

Query: 1307 IALDALSAYWIASHTTEERGLNVTLSSTGRNGFKSHALQLNNRQIRGLEEELQFSLGSKI 1366
            +   AL+ Y   +   +E  L+V+L    R+   +H +   +  +   EE  +       
Sbjct: 1    MVFQALAQYQKDAPDHQELNLDVSLQLPSRSSKITHRIHWESASLLRSEETKE---NEGF 57

Query: 1367 NVKVGGNSKGTLKVLRTYNVLDMKNTTCQDLQIEVTVKGHVEYTMEANEDYEDYEYDELP 1426
             V   G  +GTL V+  Y+       TC    ++VT+K                     P
Sbjct: 58   TVTAEGKGQGTLSVVTMYHAKAKDQLTCNKFDLKVTIK---------------------P 96

Query: 1427 AKDDPDAPLQPVTPLQLFEGRRNRRRREAPKVVEEQESRVHYTVCIWRNGKVGLSGMAIA 1486
            A +    P      + L    R R  ++A                           M+I 
Sbjct: 97   APETEKRPQDAKNTMILEICTRYRGDQDAT--------------------------MSIL 130

Query: 1487 DVTLLSGFHALRADLEKLTSLSDRYVSHFETEGPH-----VLLYFDSVPTSRE-CVGFEA 1540
            D+++++GF     DL++L +  DRY+S +E +        +++Y D V  S + C+ F+ 
Sbjct: 131  DISMMTGFAPDTDDLKQLANGVDRYISKYELDKAFSDRNTLIIYLDKVSHSEDDCLAFKV 190

Query: 1541 VQEVPVGLVQPASATLYDYYNPERRCSVFYGAPSKSRLLATLCSAEVCQCAEGKCPRQRR 1600
             Q   V L+QP +  +Y YYN E  C+ FY    +   L  LC  E+C+CAE  C  Q+ 
Sbjct: 191  HQYFNVELIQPGAVKVYAYYNLEESCTRFYHPEKEDGKLNKLCRDELCRCAEENCFIQKS 250

Query: 1601 ALERGLQDEDGYRMKFACYYPRVEYGFQVKVLREDSRAAFRLFETKITQVLHFTKDVKAA 1660
              +  L++    R+  AC  P V+Y ++ ++++      F  +   I Q +    D +  
Sbjct: 251  DDKVTLEE----RLDKAC-EPGVDYVYKTRLVKVQLSNDFDEYIMAIEQTIKSGSD-EVQ 304

Query: 1661 ANQMRNFLVRASCR--LRLEPGKEYLIMGLDGATYDLEGHPQYLLDSNSWIEEMPSERLC 1718
              Q R F+    CR  L+LE  K YL+ GL    +  + +  Y++  ++W+E  P E  C
Sbjct: 305  VGQQRTFISPIKCREALKLEEKKHYLMWGLSSDFWGEKPNLSYIIGKDTWVEHWPEEDEC 364

Query: 1719 RSTRQRAACAQLNDFLQEYGTQGC 1742
            +    +  C  L  F +     GC
Sbjct: 365  QDEENQKQCQDLGAFTESMVVFGC 388


>gi|239750255 PREDICTED: similar to ovostatin-2 [Homo sapiens]
          Length = 750

 Score = 69.3 bits (168), Expect = 3e-11
 Identities = 71/276 (25%), Positives = 117/276 (42%), Gaps = 28/276 (10%)

Query: 774  VRSFFPENWLWRVETVDRFQI--LTLWLPDSLTTWEIHGLSLSKTKGLCVATPVQLRVFR 831
            VR+ FPE W+W + +VD      L+  +PD++T WE  G  ++   G  +++   L V +
Sbjct: 362  VRTNFPETWMWDLVSVDSSGSANLSFLIPDTITQWEASGFCVNGDVGFGISSTTTLEVSQ 421

Query: 832  EFHLHLRLPMSVRRFEQLELRPVLYNYLDKNLTVSVHVSPVEGL-CLAGGGGLAQQVLVP 890
             F + +  P SV + EQ +L    ++YL+  + +SV V   +          +    ++ 
Sbjct: 422  PFFIEIASPFSVVQNEQFDLIVNAFSYLNTCVEISVQVEESQNYEANINTWKINGSEVIQ 481

Query: 891  AGSARPVAFSVVPTAAAAVSLKVVARG------------SFEFPVGDAVSKVLQIEKEGA 938
            AG  +   ++++P     V++ VVA                +    D V K   +E EG 
Sbjct: 482  AGGRKTNIWTIIPKKLGKVNITVVAESKQSSACPNEGMEQQKLNWKDTVVKSFLVEPEG- 540

Query: 939  IHREELVYELNPLDHRGRTLEIPGNSD-PNMIPDGDFNSYVRVTASDPLDTLGSEGALSP 997
            I +E     L  +   G      G  D PN + +G    +  V      D LG    L+ 
Sbjct: 541  IEKERTQSFL--ICTEGAKASKQGVLDLPNDVVEGSARGFFTVVG----DILG----LAM 590

Query: 998  GGVASLLRLPRGCGEQTMIYLAPTLAASRYLDKTEQ 1033
              +  +L++P G GEQ    LA       YL  TEQ
Sbjct: 591  QNLV-VLQMPYGGGEQNAALLASDTYVLDYLKSTEQ 625


>gi|169217711 PREDICTED: similar to Ovostatin homolog 2 [Homo
           sapiens]
          Length = 278

 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 30/98 (30%), Positives = 54/98 (55%), Gaps = 2/98 (2%)

Query: 774 VRSFFPENWLWRVETVDRFQI--LTLWLPDSLTTWEIHGLSLSKTKGLCVATPVQLRVFR 831
           VR+ FPE W+W + +VD      L+  +PD++T WE  G  ++   G  +++   L V +
Sbjct: 67  VRTNFPETWMWDLVSVDSSGSANLSFLIPDTITQWEASGFCVNGDVGFGISSTTTLEVSQ 126

Query: 832 EFHLHLRLPMSVRRFEQLELRPVLYNYLDKNLTVSVHV 869
            F + +  P SV + EQ +L   +++Y +  + +SV V
Sbjct: 127 PFFIEIASPFSVVQNEQFDLIVNVFSYRNTCVEISVQV 164


>gi|239755748 PREDICTED: ovostatin [Homo sapiens]
          Length = 257

 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 35/108 (32%), Positives = 48/108 (44%), Gaps = 2/108 (1%)

Query: 1469 TVCIWRNGKVGLSGMAIADVTLLSGFHALRADLEKLTSLSDRYVSHFETEGPHVLLYFDS 1528
            TV +   G    S M + DV +LSGF    + +E+L +     V   E +  HVL Y ++
Sbjct: 149  TVTLKYTGIRNKSSMVVIDVKMLSGFTPTMSSIEELENKGQ--VMKTEVKNDHVLFYLEN 206

Query: 1529 VPTSRECVGFEAVQEVPVGLVQPASATLYDYYNPERRCSVFYGAPSKS 1576
                 +   F   Q   V  +QPA A +YDYY  E     FY   S S
Sbjct: 207  GFGRADSFPFSVEQSNLVFNIQPAPAMVYDYYEKEEYALAFYNIDSSS 254


>gi|169205183 PREDICTED: similar to hCG38149 [Homo sapiens]
          Length = 95

 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 31/94 (32%), Positives = 43/94 (45%), Gaps = 2/94 (2%)

Query: 1483 MAIADVTLLSGFHALRADLEKLTSLSDRYVSHFETEGPHVLLYFDSVPTSRECVGFEAVQ 1542
            M + DV +LSGF    + +E+L +     V   E +  HVL Y ++     +   F   Q
Sbjct: 1    MVVIDVKMLSGFTPTMSSIEELENKGQ--VMKTEVKNDHVLFYLENGFGRADSFPFSVEQ 58

Query: 1543 EVPVGLVQPASATLYDYYNPERRCSVFYGAPSKS 1576
               V  +QPA A +YDYY  E     FY   S S
Sbjct: 59   SNLVFNIQPAPAMVYDYYEKEEYALAFYNIDSSS 92


>gi|239744557 PREDICTED: hypothetical protein LOC728715 [Homo sapiens]
          Length = 95

 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 31/94 (32%), Positives = 43/94 (45%), Gaps = 2/94 (2%)

Query: 1483 MAIADVTLLSGFHALRADLEKLTSLSDRYVSHFETEGPHVLLYFDSVPTSRECVGFEAVQ 1542
            M + DV +LSGF    + +E+L +     V   E +  HVL Y ++     +   F   Q
Sbjct: 1    MVVIDVKMLSGFTPTMSSIEELENKGQ--VMKTEVKNDHVLFYLENGFGRADSFPFSVEQ 58

Query: 1543 EVPVGLVQPASATLYDYYNPERRCSVFYGAPSKS 1576
               V  +QPA A +YDYY  E     FY   S S
Sbjct: 59   SNLVFNIQPAPAMVYDYYEKEEYALAFYNIDSSS 92


>gi|239755754 PREDICTED: ovostatin 2 [Homo sapiens]
          Length = 164

 Score = 38.1 bits (87), Expect = 0.075
 Identities = 21/61 (34%), Positives = 27/61 (44%)

Query: 1516 ETEGPHVLLYFDSVPTSRECVGFEAVQEVPVGLVQPASATLYDYYNPERRCSVFYGAPSK 1575
            E +  HVL Y ++     +   F   Q   V  +QPA A +YDYY  E     FY   S 
Sbjct: 101  EVKNDHVLFYLENGFGRADSFPFSVEQSNLVFNIQPAPAMVYDYYEKEEYALAFYNIDSS 160

Query: 1576 S 1576
            S
Sbjct: 161  S 161


>gi|21359951 RNA binding motif protein 42 [Homo sapiens]
          Length = 480

 Score = 38.1 bits (87), Expect = 0.075
 Identities = 29/83 (34%), Positives = 42/83 (50%), Gaps = 8/83 (9%)

Query: 391 REMSGSPASGIPVKVSATVSSPGSVPEVQDIQQNTDGSGQVSIPIIIPQTISELQLSVSA 450
           +E+ G+P  GIP  V A  + P +VP V+ +Q     +  V  PII   T  ++Q ++ A
Sbjct: 46  QEVLGAPVPGIPTAVPAVPTVP-TVPTVEAMQV---PAAPVIRPIIATNTYQQVQQTLEA 101

Query: 451 GSPHPAIARLTVAAPPSGGPGFL 473
                A A  TV  P  GGP F+
Sbjct: 102 ----RAAAAATVVPPMVGGPPFV 120


>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sapiens]
          Length = 2462

 Score = 33.1 bits (74), Expect = 2.4
 Identities = 30/107 (28%), Positives = 47/107 (43%), Gaps = 8/107 (7%)

Query: 871  PVEGLCLAGGGGLAQQVLVPAGSARPVAFSVVPTAAAAVSLKVVARGSFEFPVGDAVSKV 930
            P++   LA   G+ Q+ L P G A P     VPTA  A  L+  A GS     G +++K 
Sbjct: 1146 PMDPKKLAPFSGVKQEQLSPRGQAGPPESLGVPTAQEASVLRGTALGSVP---GGSITKG 1202

Query: 931  L---QIEKEGAIHREELVYELNPLD--HRGRTLEIPGNSDPNMIPDG 972
            +   ++  + AI     +    P D  ++G    I G   P+ +  G
Sbjct: 1203 IPSTRVPSDSAITYRGSITHGTPADVLYKGTITRIIGEDSPSRLDRG 1249


>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sapiens]
          Length = 2524

 Score = 33.1 bits (74), Expect = 2.4
 Identities = 30/107 (28%), Positives = 47/107 (43%), Gaps = 8/107 (7%)

Query: 871  PVEGLCLAGGGGLAQQVLVPAGSARPVAFSVVPTAAAAVSLKVVARGSFEFPVGDAVSKV 930
            P++   LA   G+ Q+ L P G A P     VPTA  A  L+  A GS     G +++K 
Sbjct: 1162 PMDPKKLAPFSGVKQEQLSPRGQAGPPESLGVPTAQEASVLRGTALGSVP---GGSITKG 1218

Query: 931  L---QIEKEGAIHREELVYELNPLD--HRGRTLEIPGNSDPNMIPDG 972
            +   ++  + AI     +    P D  ++G    I G   P+ +  G
Sbjct: 1219 IPSTRVPSDSAITYRGSITHGTPADVLYKGTITRIIGEDSPSRLDRG 1265


>gi|109689723 abl interactor 2 [Homo sapiens]
          Length = 475

 Score = 33.1 bits (74), Expect = 2.4
 Identities = 27/90 (30%), Positives = 37/90 (41%), Gaps = 29/90 (32%)

Query: 406 SATVSSPGSVPEVQDIQQNTDGSGQVSIPIIIPQTISELQLSVSAGSPHPAIARLTVAAP 465
           S++ SS GS P  +   +   GSG V +PI +P                         +P
Sbjct: 236 SSSGSSGGSHPSSRSSSRENSGSGSVGVPIAVP-----------------------TPSP 272

Query: 466 PSGGPG----FLSIEWPDSR--PPRVGDTL 489
           PS  PG    F S+  P SR  PP +G +L
Sbjct: 273 PSVFPGHPVQFYSMNRPASRHTPPTIGGSL 302


>gi|120587027 ubiquitin specific peptidase 31 [Homo sapiens]
          Length = 1352

 Score = 33.1 bits (74), Expect = 2.4
 Identities = 34/110 (30%), Positives = 49/110 (44%), Gaps = 9/110 (8%)

Query: 347  YPGGEMEEAELTSWYFVSSPFSLDLSKTKRHLVPGAPFLLQALVREMSGSPASGIPVKVS 406
            +PG   ++ E T+     SP S   S+ ++ L  G P L        S SP+S +PVKVS
Sbjct: 1011 HPGSLAKKPESTT---KRSPSSKGTSEPEKSLRKGRPALASQESSLSSTSPSSPLPVKVS 1067

Query: 407  ATVSSPGSVPEVQDIQQNTDGSGQVSIPI-IIPQTISELQLSVSAGSPHP 455
               S   S  +      ++ GSG+ S P    P+  S  +   S  SP P
Sbjct: 1068 LKPSRSRSKAD-----SSSRGSGRHSSPAPAQPKKESSPKSQDSVSSPSP 1112


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.134    0.398 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 68,565,271
Number of Sequences: 37866
Number of extensions: 3283822
Number of successful extensions: 9239
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 9018
Number of HSP's gapped (non-prelim): 83
length of query: 1744
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1628
effective length of database: 13,855,062
effective search space: 22556040936
effective search space used: 22556040936
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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