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Search of human proteins with 239582745
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239582745 RAN binding protein 3-like isoform 1 [Homo
sapiens]
(490 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239582745 RAN binding protein 3-like isoform 1 [Homo sapiens] 975 0.0
gi|239582743 RAN binding protein 3-like isoform 2 [Homo sapiens] 910 0.0
gi|194097489 RAN binding protein 3 isoform RANBP3-b [Homo sapiens] 241 8e-64
gi|6466466 RAN binding protein 3 isoform RANBP3-d [Homo sapiens] 233 4e-61
gi|194097487 RAN binding protein 3 isoform RANBP3-a [Homo sapiens] 231 1e-60
gi|157266273 RANBP2-like and GRIP domain containing 1 [Homo sapi... 54 4e-07
gi|118200331 RANBP2-like and GRIP domain containing 2 [Homo sapi... 54 4e-07
gi|211059431 RANBP2-like and GRIP domain containing 4 [Homo sapi... 54 4e-07
gi|221307607 RANBP2-like and GRIP domain containing 3 [Homo sapi... 48 2e-05
gi|169162953 PREDICTED: RANBP2-like and GRIP domain containing 8... 47 3e-05
gi|83267877 RANBP2-like and GRIP domain containing 5 isoform 1 [... 47 5e-05
gi|182765478 RANBP2-like and GRIP domain containing 6 [Homo sapi... 47 5e-05
gi|150418007 RAN binding protein 2 [Homo sapiens] 45 1e-04
gi|4506407 RAN binding protein 1 [Homo sapiens] 34 0.34
gi|19923191 minichromosome maintenance complex component 3 assoc... 33 0.45
gi|61743980 stabilin 2 precursor [Homo sapiens] 33 0.59
gi|14149991 RANBP2-like and GRIP domain containing 5 isoform 2 [... 33 0.77
gi|118197270 RANBP2-like and GRIP domain containing 7 [Homo sapi... 33 0.77
gi|4507575 tumor necrosis factor receptor 1 precursor [Homo sapi... 32 1.7
gi|24497447 nucleoporin 50kDa isoform a [Homo sapiens] 32 1.7
gi|24497451 nucleoporin 50kDa isoform b [Homo sapiens] 32 1.7
gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 30 6.5
gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 30 6.5
gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 30 6.5
gi|203096856 kinesin family member 7 [Homo sapiens] 30 6.5
gi|7019499 peroxisome proliferator-activated receptor gamma, coa... 29 8.5
gi|217416354 sphingosine kinase type 1-interacting protein isofo... 29 8.5
gi|217416352 sphingosine kinase type 1-interacting protein isofo... 29 8.5
>gi|239582745 RAN binding protein 3-like isoform 1 [Homo sapiens]
Length = 490
Score = 975 bits (2520), Expect = 0.0
Identities = 490/490 (100%), Positives = 490/490 (100%)
Query: 1 MTTIPRKGSSHLPGSLHTCKLKLQEDRRQQEKSVIAQPIFVFEKGEQTFKRPAEDTLYEA 60
MTTIPRKGSSHLPGSLHTCKLKLQEDRRQQEKSVIAQPIFVFEKGEQTFKRPAEDTLYEA
Sbjct: 1 MTTIPRKGSSHLPGSLHTCKLKLQEDRRQQEKSVIAQPIFVFEKGEQTFKRPAEDTLYEA 60
Query: 61 AEPECNGFPTKRVRSSSFTFHITDSQSQGVSTLSQKQMRCSSVTNLPTFPHSGPVRKNNV 120
AEPECNGFPTKRVRSSSFTFHITDSQSQGVSTLSQKQMRCSSVTNLPTFPHSGPVRKNNV
Sbjct: 61 AEPECNGFPTKRVRSSSFTFHITDSQSQGVSTLSQKQMRCSSVTNLPTFPHSGPVRKNNV 120
Query: 121 FMTSALVQSSVDIKSAEQGPVKHSKHVIRPAILQLPQARSCAKVRKTFGHKALESCKTKE 180
FMTSALVQSSVDIKSAEQGPVKHSKHVIRPAILQLPQARSCAKVRKTFGHKALESCKTKE
Sbjct: 121 FMTSALVQSSVDIKSAEQGPVKHSKHVIRPAILQLPQARSCAKVRKTFGHKALESCKTKE 180
Query: 181 KTNNKISEGNSYLLSENLSRARISVQLSTNQDFLGATSVGCQPNEDKCSFKSCSSNFVFG 240
KTNNKISEGNSYLLSENLSRARISVQLSTNQDFLGATSVGCQPNEDKCSFKSCSSNFVFG
Sbjct: 181 KTNNKISEGNSYLLSENLSRARISVQLSTNQDFLGATSVGCQPNEDKCSFKSCSSNFVFG 240
Query: 241 ENMVERVLGTQKLTQPQLENDSYAKEKPFKSIPKFPVNFLSSRTDSIKNTSLIESAAAFS 300
ENMVERVLGTQKLTQPQLENDSYAKEKPFKSIPKFPVNFLSSRTDSIKNTSLIESAAAFS
Sbjct: 241 ENMVERVLGTQKLTQPQLENDSYAKEKPFKSIPKFPVNFLSSRTDSIKNTSLIESAAAFS 300
Query: 301 SQPSRKCLLEKIDVITGEETEHNVLKINCKLFIFNKTTQSWIERGRGTLRLNDTASTDCG 360
SQPSRKCLLEKIDVITGEETEHNVLKINCKLFIFNKTTQSWIERGRGTLRLNDTASTDCG
Sbjct: 301 SQPSRKCLLEKIDVITGEETEHNVLKINCKLFIFNKTTQSWIERGRGTLRLNDTASTDCG 360
Query: 361 TLQSRLIMRNQGSLRLILNSKLWAQMKIQRANHKNVRITATDLEDYSIKIFLIQASAQDT 420
TLQSRLIMRNQGSLRLILNSKLWAQMKIQRANHKNVRITATDLEDYSIKIFLIQASAQDT
Sbjct: 361 TLQSRLIMRNQGSLRLILNSKLWAQMKIQRANHKNVRITATDLEDYSIKIFLIQASAQDT 420
Query: 421 AYLYAAIHHRLVALQSFNKQRDVNQAESLSETAQQLNCESCDENEDDFIQVTKNGSDPSS 480
AYLYAAIHHRLVALQSFNKQRDVNQAESLSETAQQLNCESCDENEDDFIQVTKNGSDPSS
Sbjct: 421 AYLYAAIHHRLVALQSFNKQRDVNQAESLSETAQQLNCESCDENEDDFIQVTKNGSDPSS 480
Query: 481 WTHRQSVACS 490
WTHRQSVACS
Sbjct: 481 WTHRQSVACS 490
>gi|239582743 RAN binding protein 3-like isoform 2 [Homo sapiens]
Length = 465
Score = 910 bits (2352), Expect = 0.0
Identities = 465/490 (94%), Positives = 465/490 (94%), Gaps = 25/490 (5%)
Query: 1 MTTIPRKGSSHLPGSLHTCKLKLQEDRRQQEKSVIAQPIFVFEKGEQTFKRPAEDTLYEA 60
MTTIPRKGSSHLPGSLHTCKLKLQEDRRQQEKSVIAQPIFVFEKGEQTFKRPAEDTLYEA
Sbjct: 1 MTTIPRKGSSHLPGSLHTCKLKLQEDRRQQEKSVIAQPIFVFEKGEQTFKRPAEDTLYEA 60
Query: 61 AEPECNGFPTKRVRSSSFTFHITDSQSQGVSTLSQKQMRCSSVTNLPTFPHSGPVRKNNV 120
AEPECNGFPTKRVRSSSFTFHITDSQSQGV RKNNV
Sbjct: 61 AEPECNGFPTKRVRSSSFTFHITDSQSQGV-------------------------RKNNV 95
Query: 121 FMTSALVQSSVDIKSAEQGPVKHSKHVIRPAILQLPQARSCAKVRKTFGHKALESCKTKE 180
FMTSALVQSSVDIKSAEQGPVKHSKHVIRPAILQLPQARSCAKVRKTFGHKALESCKTKE
Sbjct: 96 FMTSALVQSSVDIKSAEQGPVKHSKHVIRPAILQLPQARSCAKVRKTFGHKALESCKTKE 155
Query: 181 KTNNKISEGNSYLLSENLSRARISVQLSTNQDFLGATSVGCQPNEDKCSFKSCSSNFVFG 240
KTNNKISEGNSYLLSENLSRARISVQLSTNQDFLGATSVGCQPNEDKCSFKSCSSNFVFG
Sbjct: 156 KTNNKISEGNSYLLSENLSRARISVQLSTNQDFLGATSVGCQPNEDKCSFKSCSSNFVFG 215
Query: 241 ENMVERVLGTQKLTQPQLENDSYAKEKPFKSIPKFPVNFLSSRTDSIKNTSLIESAAAFS 300
ENMVERVLGTQKLTQPQLENDSYAKEKPFKSIPKFPVNFLSSRTDSIKNTSLIESAAAFS
Sbjct: 216 ENMVERVLGTQKLTQPQLENDSYAKEKPFKSIPKFPVNFLSSRTDSIKNTSLIESAAAFS 275
Query: 301 SQPSRKCLLEKIDVITGEETEHNVLKINCKLFIFNKTTQSWIERGRGTLRLNDTASTDCG 360
SQPSRKCLLEKIDVITGEETEHNVLKINCKLFIFNKTTQSWIERGRGTLRLNDTASTDCG
Sbjct: 276 SQPSRKCLLEKIDVITGEETEHNVLKINCKLFIFNKTTQSWIERGRGTLRLNDTASTDCG 335
Query: 361 TLQSRLIMRNQGSLRLILNSKLWAQMKIQRANHKNVRITATDLEDYSIKIFLIQASAQDT 420
TLQSRLIMRNQGSLRLILNSKLWAQMKIQRANHKNVRITATDLEDYSIKIFLIQASAQDT
Sbjct: 336 TLQSRLIMRNQGSLRLILNSKLWAQMKIQRANHKNVRITATDLEDYSIKIFLIQASAQDT 395
Query: 421 AYLYAAIHHRLVALQSFNKQRDVNQAESLSETAQQLNCESCDENEDDFIQVTKNGSDPSS 480
AYLYAAIHHRLVALQSFNKQRDVNQAESLSETAQQLNCESCDENEDDFIQVTKNGSDPSS
Sbjct: 396 AYLYAAIHHRLVALQSFNKQRDVNQAESLSETAQQLNCESCDENEDDFIQVTKNGSDPSS 455
Query: 481 WTHRQSVACS 490
WTHRQSVACS
Sbjct: 456 WTHRQSVACS 465
>gi|194097489 RAN binding protein 3 isoform RANBP3-b [Homo sapiens]
Length = 499
Score = 241 bits (616), Expect = 8e-64
Identities = 180/487 (36%), Positives = 256/487 (52%), Gaps = 55/487 (11%)
Query: 26 DRRQQEKSVIAQPIFVFEKGEQTFKRPAEDTLYEAAEP---ECNGF--PTKRVRSSSFTF 80
D +EK IA P+FVF+K ++ KR A + E E E + P KR R+SS T
Sbjct: 3 DLANEEKPAIAPPVFVFQK-DKGQKRSAGGSSPEGGEDSDREDGNYCPPVKRERTSSLT- 60
Query: 81 HITDSQSQGVSTLSQKQMRCSSVTNLPT--FPHSGPVRKNNVFMTSALVQSSVDIKSAEQ 138
SQS+ S+ + + P+ P P + + A++Q+ ++
Sbjct: 61 QFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAVLQAPQPKALSQT 120
Query: 139 GPVKHSKHVIRPAILQ--LPQARSCAKVRKTFGHKALESCKTKEKTNNKISEGNSY---- 192
P + V PA +P A ++ A E C +EK K N+
Sbjct: 121 VPSSGTNGVSLPADCTGAVPAASPDTAAWRSPSEAADEVCALEEKEPQKNESSNASEEEA 180
Query: 193 -----------------------LLSENLSRARISVQLSTNQDFLGATSVGCQ----PNE 225
L++E++ A + + D AT+ Q E
Sbjct: 181 CEKKDPATQQAFVFGQNLRDRVKLINESVDEADMENAGHPSADTPTATNYFLQYISSSLE 240
Query: 226 DKCSFKSCSSN-FVFGENMVERVLGTQKLTQPQLE--NDSYAKEKPFKSIPKFPVNFLSS 282
+ + SSN FVFG+NM ERVL KL + + ++ A E +S SS
Sbjct: 241 NSTNSADASSNKFVFGQNMSERVLSPPKLNEVSSDANRENAAAESGSES---------SS 291
Query: 283 RTDSIKNTSLIESAAAFSSQPSRKCLLEKIDVITGEETEHNVLKINCKLFIFNKTTQSWI 342
+ + + SL ESAAA++ +RKCLLEK++VITGEE E NVL++ CKLF+F+KT+QSW+
Sbjct: 292 QEATPEKESLAESAAAYTKATARKCLLEKVEVITGEEAESNVLQMQCKLFVFDKTSQSWV 351
Query: 343 ERGRGTLRLNDTASTDCGTLQSRLIMRNQGSLRLILNSKLWAQMKIQRANHKNVRITATD 402
ERGRG LRLND ASTD GTLQSRL+MR QGSLRLILN+KLWAQM+I +A+ K++RITA D
Sbjct: 352 ERGRGLLRLNDMASTDDGTLQSRLVMRTQGSLRLILNTKLWAQMQIDKASEKSIRITAMD 411
Query: 403 LEDYSIKIFLIQASAQDTAYLYAAIHHRLVALQSFNKQRDVNQAESLSETAQQLNCESCD 462
ED +K+FLI AS++DT LYAA+HHR++AL+S +Q + + A N E D
Sbjct: 412 TEDQGVKVFLISASSKDTGQLYAALHHRILALRSRVEQEQEAKMPAPEPGAAPSN-EEDD 470
Query: 463 ENEDDFI 469
++DD +
Sbjct: 471 SDDDDVL 477
>gi|6466466 RAN binding protein 3 isoform RANBP3-d [Homo sapiens]
Length = 567
Score = 233 bits (593), Expect = 4e-61
Identities = 163/439 (37%), Positives = 230/439 (52%), Gaps = 78/439 (17%)
Query: 96 KQMRCSSVTNLPTFPHSGPVRKNNVFMTSALVQSSVDIKSA---EQGPVKHSKHVIRPAI 152
K+ R SS+T FP S +++ F SA Q P + + V+RPA+
Sbjct: 120 KRERTSSLTQ---FPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAV 176
Query: 153 LQLPQARSCAKVRKTFGHKAL----------------------------ESCKTKEKTNN 184
LQ PQ ++ ++ + G + E C +EK
Sbjct: 177 LQAPQPKALSQTVPSSGTNGVSLPADCTGAVPAASPDTAAWRSPSEAADEVCALEEKEPQ 236
Query: 185 KISEGNSY---------------------------LLSENLSRARISVQLSTNQDFLGAT 217
K N+ L++E++ A + + D AT
Sbjct: 237 KNESSNASEEEACEKKDPATQQAFVFGQNLRDRVKLINESVDEADMENAGHPSADTPTAT 296
Query: 218 SVGCQ----PNEDKCSFKSCSSN-FVFGENMVERVLGTQKLTQPQLE--NDSYAKEKPFK 270
+ Q E+ + SSN FVFG+NM ERVL KL + + ++ A E +
Sbjct: 297 NYFLQYISSSLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVSSDANRENAAAESGSE 356
Query: 271 SIPKFPVNFLSSRTDSIKNTSLIESAAAFSSQPSRKCLLEKIDVITGEETEHNVLKINCK 330
S SS+ + + SL ESAAA++ +RKCLLEK++VITGEE E NVL++ CK
Sbjct: 357 S---------SSQEATPEKESLAESAAAYTKATARKCLLEKVEVITGEEAESNVLQMQCK 407
Query: 331 LFIFNKTTQSWIERGRGTLRLNDTASTDCGTLQSRLIMRNQGSLRLILNSKLWAQMKIQR 390
LF+F+KT+QSW+ERGRG LRLND ASTD GTLQSRL+MR QGSLRLILN+KLWAQM+I +
Sbjct: 408 LFVFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVMRTQGSLRLILNTKLWAQMQIDK 467
Query: 391 ANHKNVRITATDLEDYSIKIFLIQASAQDTAYLYAAIHHRLVALQSFNKQRDVNQAESLS 450
A+ K++RITA D ED +K+FLI AS++DT LYAA+HHR++AL+S +Q + +
Sbjct: 468 ASEKSIRITAMDTEDQGVKVFLISASSKDTGQLYAALHHRILALRSRVEQEQEAKMPAPE 527
Query: 451 ETAQQLNCESCDENEDDFI 469
A N E D ++DD +
Sbjct: 528 PGAAPSN-EEDDSDDDDVL 545
>gi|194097487 RAN binding protein 3 isoform RANBP3-a [Homo sapiens]
Length = 562
Score = 231 bits (588), Expect = 1e-60
Identities = 126/243 (51%), Positives = 169/243 (69%), Gaps = 12/243 (4%)
Query: 229 SFKSCSSNFVFGENMVERVLGTQKLTQPQLE--NDSYAKEKPFKSIPKFPVNFLSSRTDS 286
S + S+ FVFG+NM ERVL KL + + ++ A E +S SS+ +
Sbjct: 308 SADASSNKFVFGQNMSERVLSPPKLNEVSSDANRENAAAESGSES---------SSQEAT 358
Query: 287 IKNTSLIESAAAFSSQPSRKCLLEKIDVITGEETEHNVLKINCKLFIFNKTTQSWIERGR 346
+ SL ESAAA++ +RKCLLEK++VITGEE E NVL++ CKLF+F+KT+QSW+ERGR
Sbjct: 359 PEKESLAESAAAYTKATARKCLLEKVEVITGEEAESNVLQMQCKLFVFDKTSQSWVERGR 418
Query: 347 GTLRLNDTASTDCGTLQSRLIMRNQGSLRLILNSKLWAQMKIQRANHKNVRITATDLEDY 406
G LRLND ASTD GTLQSRL+MR QGSLRLILN+KLWAQM+I +A+ K++RITA D ED
Sbjct: 419 GLLRLNDMASTDDGTLQSRLVMRTQGSLRLILNTKLWAQMQIDKASEKSIRITAMDTEDQ 478
Query: 407 SIKIFLIQASAQDTAYLYAAIHHRLVALQSFNKQRDVNQAESLSETAQQLNCESCDENED 466
+K+FLI AS++DT LYAA+HHR++AL+S +Q + + A N E D ++D
Sbjct: 479 GVKVFLISASSKDTGQLYAALHHRILALRSRVEQEQEAKMPAPEPGAAPSN-EEDDSDDD 537
Query: 467 DFI 469
D +
Sbjct: 538 DVL 540
>gi|157266273 RANBP2-like and GRIP domain containing 1 [Homo sapiens]
Length = 1756
Score = 53.5 bits (127), Expect = 4e-07
Identities = 78/336 (23%), Positives = 136/336 (40%), Gaps = 34/336 (10%)
Query: 138 QGPVKHSKHVIRPAILQLPQARSCAKVRKTFGHKALESCKTKEKTNNKIS-EGNSYLLSE 196
Q P +S++++RPA A V T G E TKE + +S +G + +SE
Sbjct: 872 QSPAYNSQYLLRPA----------ANVTPTKGSSNTEFKSTKEGFSIAVSADGFKFGISE 921
Query: 197 NLSRARISVQLSTNQDFLGATSVGCQPNEDKCSFKSCSSNFVFGENMVERVLGTQKLT-- 254
++ + S + N A + Q N F SS F F + V + +
Sbjct: 922 PGNQEKKSEKPLENDTGFQAQDISGQKNGRGVIFGQTSSTFTFAD--VAKSTSGEGFQFG 979
Query: 255 --QPQLENDSYAKEKPFKSIPKFPVNFLSSRTDSIKNTSLI--ESAAAFSSQPSRKCLLE 310
P + S A EK F S N ++ D K+ E + +P + + E
Sbjct: 980 KKDPNFKGFSGAGEKLFSSQCGKMANKANTSGDFEKDDDACKTEDSDDIHFEPVVQ-MPE 1038
Query: 311 KIDVITGEETEHNVLKINCKLFIFNKTTQSWIERGRGTLRLNDTASTDCGTLQSRLIMRN 370
K++++TGEE E + KLF F+ W ERG G L++ + R++MR
Sbjct: 1039 KVELVTGEEGEKVLYSQGVKLFRFDAEISQWKERGLGNLKILKNEVNG----KPRMLMRR 1094
Query: 371 QGSLRLILNSKLWAQMKIQ--RANHKNVRITATDLEDYSIKIFLIQAS------AQDTAY 422
L++ N + M ++ + + A+D D K+ + A A++
Sbjct: 1095 DQVLKVCANHWITTTMNLKPLSGSDRAWMWLASDFSDGDAKLERLAAQFKTPELAEEFKQ 1154
Query: 423 LYAAIHHRL--VALQSFNKQRDVNQAESLSETAQQL 456
+ L + LQ+ +K D +A L + A+++
Sbjct: 1155 KFEECQRLLLDIPLQTPHKLVDTGRAAKLIQRAEEM 1190
Score = 44.3 bits (103), Expect = 3e-04
Identities = 43/191 (22%), Positives = 74/191 (38%), Gaps = 39/191 (20%)
Query: 308 LLEKIDVITGEETEHNVLKINCKLFIFNKTTQSWIERGRGTLRLNDTASTDCGTLQSRLI 367
L + ++V +GEE E V +L+ ++K W ERG G +++ Q R++
Sbjct: 1333 LPDLVEVSSGEENEQVVFSHRAELYRYDKDVGQWKERGIGDIKILQNYDNK----QVRIV 1388
Query: 368 MRNQGSLRLILNSKLWAQMKIQ---------------------RANHKNVRITATDLEDY 406
MR L+L N ++ M +Q + H VR D+ D
Sbjct: 1389 MRRDQVLKLCANHRITPDMSLQNMKGTERVWVWTACDFADGERKVEHLAVRFKLQDVADS 1448
Query: 407 SIKIFLIQASAQDTAYLYAAIHHR-------------LVALQSFNKQR-DVNQAESLSET 452
KIF +AQ+ L R + L+ ++R DV Q + +++
Sbjct: 1449 FKKIFDEAKTAQEKDSLITPHVSRSSTPRESPCGKIAVAVLEETTRERTDVIQGDDVADA 1508
Query: 453 AQQLNCESCDE 463
A ++ S E
Sbjct: 1509 ASEVEVSSTSE 1519
>gi|118200331 RANBP2-like and GRIP domain containing 2 [Homo
sapiens]
Length = 1013
Score = 53.5 bits (127), Expect = 4e-07
Identities = 78/336 (23%), Positives = 136/336 (40%), Gaps = 34/336 (10%)
Query: 138 QGPVKHSKHVIRPAILQLPQARSCAKVRKTFGHKALESCKTKEKTNNKIS-EGNSYLLSE 196
Q P +S++++RPA A V T G E TKE + +S +G + +SE
Sbjct: 129 QSPAYNSQYLLRPA----------ANVTPTKGSSNTEFKSTKEGFSIAVSADGFKFGISE 178
Query: 197 NLSRARISVQLSTNQDFLGATSVGCQPNEDKCSFKSCSSNFVFGENMVERVLGTQKLT-- 254
++ + S + N A + Q N F SS F F + V + +
Sbjct: 179 PGNQEKKSEKPLENDTGFQAQDISGQKNGRGVIFGQTSSTFTFAD--VAKSTSGEGFQFG 236
Query: 255 --QPQLENDSYAKEKPFKSIPKFPVNFLSSRTDSIKNTSLI--ESAAAFSSQPSRKCLLE 310
P + S A EK F S N ++ D K+ E + +P + + E
Sbjct: 237 KKDPNFKGFSGAGEKLFSSQCGKMANKANTSGDFEKDDDACKTEDSDDIHFEPVVQ-MPE 295
Query: 311 KIDVITGEETEHNVLKINCKLFIFNKTTQSWIERGRGTLRLNDTASTDCGTLQSRLIMRN 370
K++++TGEE E + KLF F+ W ERG G L++ + R++MR
Sbjct: 296 KVELVTGEEGEKVLYSQGVKLFRFDAEISQWKERGLGNLKILKNEVNG----KPRMLMRR 351
Query: 371 QGSLRLILNSKLWAQMKIQ--RANHKNVRITATDLEDYSIKIFLIQAS------AQDTAY 422
L++ N + M ++ + + A+D D K+ + A A++
Sbjct: 352 DQVLKVCANHWITTTMNLKPLSGSDRAWMWLASDFSDGDAKLERLAAQFKTPELAEEFKQ 411
Query: 423 LYAAIHHRL--VALQSFNKQRDVNQAESLSETAQQL 456
+ L + LQ+ +K D +A L + A+++
Sbjct: 412 KFEECQRLLLDIPLQTPHKLVDTGRAAKLIQRAEEM 447
Score = 43.5 bits (101), Expect = 4e-04
Identities = 43/191 (22%), Positives = 74/191 (38%), Gaps = 39/191 (20%)
Query: 308 LLEKIDVITGEETEHNVLKINCKLFIFNKTTQSWIERGRGTLRLNDTASTDCGTLQSRLI 367
L + ++V +GEE E V +L+ ++K W ERG G +++ Q R++
Sbjct: 590 LPDLVEVSSGEENEQVVFSHMAELYRYDKDVGQWKERGIGDIKILQNYDNK----QVRIV 645
Query: 368 MRNQGSLRLILNSKLWAQMKIQ---------------------RANHKNVRITATDLEDY 406
MR L+L N ++ M +Q + H VR D+ D
Sbjct: 646 MRRDQVLKLCANHRITPDMSLQNMKGTERVWVWTACDFADGERKVEHLAVRFKLQDVADS 705
Query: 407 SIKIFLIQASAQDTAYLYAAIHHR-------------LVALQSFNKQR-DVNQAESLSET 452
KIF +AQ+ L R + L+ ++R DV Q + +++
Sbjct: 706 FKKIFDEAKTAQEKDSLITPHVSRSSTPRESPCGKIAVAVLEETTRERTDVIQGDDVADA 765
Query: 453 AQQLNCESCDE 463
A ++ S E
Sbjct: 766 ASEVEVSSTSE 776
>gi|211059431 RANBP2-like and GRIP domain containing 4 [Homo sapiens]
Length = 1758
Score = 53.5 bits (127), Expect = 4e-07
Identities = 77/336 (22%), Positives = 138/336 (41%), Gaps = 34/336 (10%)
Query: 138 QGPVKHSKHVIRPAILQLPQARSCAKVRKTFGHKALESCKTKEKTNNKIS-EGNSYLLSE 196
Q P +S++++RPA A V T G E TKE + +S +G + +SE
Sbjct: 880 QSPAYNSQYLLRPA----------ANVTPTKGSSNTEFKSTKEGFSIPVSADGFKFGISE 929
Query: 197 NLSRARISVQLSTNQDFLGATSVGCQPNEDKCSFKSCSSNFVFGENMVERVLGTQKLT-- 254
++ + S + N A + Q N F SS F F + V + +
Sbjct: 930 PGNQEKESEKPLENDTGFQAQDISGQKNGRGVIFGQTSSTFTFAD--VAKSTSGEGFQFG 987
Query: 255 --QPQLENDSYAKEKPFKSIPKFPVNFLSSRTDSIKNTSLI--ESAAAFSSQPSRKCLLE 310
P + S A EK F S N ++ D K+ E + +P + + E
Sbjct: 988 KKDPNFKGFSGAGEKLFSSQCGKMANKANTSGDFEKDDDAYKTEDSDDIHFEPVVQ-MPE 1046
Query: 311 KIDVITGEETEHNVLKINCKLFIFNKTTQSWIERGRGTLRLNDTASTDCGTLQSRLIMRN 370
K++++ GEE E + KLF F+ + W ERG G L++ + R++MR
Sbjct: 1047 KVELVIGEEGEKVLYSQGVKLFRFDAEVRQWKERGLGNLKILKNEVNG----KPRMLMRR 1102
Query: 371 QGSLRLILNSKLWAQMKIQ--RANHKNVRITATDLEDYSIKIFLIQAS------AQDTAY 422
+ L++ N + M ++ + + +A+D D K+ + A A++
Sbjct: 1103 EQVLKVCANHWITTTMNLKPLSGSDRAWMWSASDFSDGDAKLERLAAKFKTPELAEEFKQ 1162
Query: 423 LYAAIHHRL--VALQSFNKQRDVNQAESLSETAQQL 456
+ L + LQ+ +K D +A L + A+++
Sbjct: 1163 KFEECQQLLLDIPLQTPHKLVDTGRAAKLIQRAEEM 1198
Score = 42.7 bits (99), Expect = 7e-04
Identities = 43/191 (22%), Positives = 73/191 (38%), Gaps = 39/191 (20%)
Query: 308 LLEKIDVITGEETEHNVLKINCKLFIFNKTTQSWIERGRGTLRLNDTASTDCGTLQSRLI 367
L + ++V +GEE E V +L+ ++K W ERG G +++ Q R++
Sbjct: 1341 LPDLVEVSSGEENEKVVFSHRAELYRYDKDVGQWKERGIGDIKILQNYDNK----QVRIV 1396
Query: 368 MRNQGSLRLILNSKLWAQMKIQ---------------------RANHKNVRITATDLEDY 406
MR L+L N + M +Q + H VR D+ D
Sbjct: 1397 MRRDQVLKLCANHTITPDMSLQNMKGTERVWVWTACDFADGERKVEHLAVRFKLQDVADS 1456
Query: 407 SIKIFLIQASAQDTAYLYAAIHHR-------------LVALQSFNKQR-DVNQAESLSET 452
KIF +AQ+ L R + L+ ++R DV Q + +++
Sbjct: 1457 FKKIFDEAKTAQEKDSLITPHVSRSSTPRESPCGKIAVAVLEETTRERTDVIQGDDVADA 1516
Query: 453 AQQLNCESCDE 463
A ++ S E
Sbjct: 1517 ASEVEVSSTSE 1527
>gi|221307607 RANBP2-like and GRIP domain containing 3 [Homo sapiens]
Length = 1758
Score = 48.1 bits (113), Expect = 2e-05
Identities = 74/334 (22%), Positives = 136/334 (40%), Gaps = 30/334 (8%)
Query: 138 QGPVKHSKHVIRPAILQLPQARSCAKVRKTFGHKALESCKTKEKTNNKIS-EGNSYLLSE 196
Q P +S++++RPA A V T G E TKE + +S +G + +SE
Sbjct: 880 QSPAYNSQYLLRPA----------ANVTPTKGSSNTEFKSTKEGFSIPVSADGFKFGISE 929
Query: 197 NLSRARISVQLSTNQDFLGATSVGCQPNEDKCSFKSCSSNFVFGENMVERVLGTQKLTQP 256
++ + S + N L A + + F SS F F + + +
Sbjct: 930 PGNQEKKSEKPLENDTGLQAQDISGRKKGRGVIFGQTSSTFTFADVAKSTSGEGFQFGKK 989
Query: 257 QLENDSY--AKEKPFKSIPKFPVNFLSSRTDSIKNTSLI--ESAAAFSSQPSRKCLLEKI 312
L + A EK F S N ++ D K+ E + +P + + EK+
Sbjct: 990 DLNFKGFSGAGEKLFSSQYGKMANKANTSGDFEKDDDAYKTEDSDDIHFEPVVQ-MPEKV 1048
Query: 313 DVITGEETEHNVLKINCKLFIFNKTTQSWIERGRGTLRLNDTASTDCGTLQSRLIMRNQG 372
+++TGEE E + KLF F+ W ERG G L++ + R++M+ +
Sbjct: 1049 ELVTGEEGEKVLYSQGVKLFRFDAEVSQWKERGLGNLKILKNEVNG----KVRMLMQREQ 1104
Query: 373 SLRLILNSKLWAQMKIQ--RANHKNVRITATDLEDYSIKIFLIQAS------AQDTAYLY 424
L++ N + M ++ + + +A+D D K+ + A A++ +
Sbjct: 1105 VLKVCANHWITTTMNLKPLSGSDRAWMWSASDFSDGDAKLERLAAKFKTPELAEEFKQKF 1164
Query: 425 AAIHHRL--VALQSFNKQRDVNQAESLSETAQQL 456
L + LQ+ +K D +A L + A+++
Sbjct: 1165 EECQRLLLDIPLQTPHKLVDTGRAAKLIQRAEEM 1198
Score = 40.4 bits (93), Expect = 0.004
Identities = 41/191 (21%), Positives = 72/191 (37%), Gaps = 39/191 (20%)
Query: 308 LLEKIDVITGEETEHNVLKINCKLFIFNKTTQSWIERGRGTLRLNDTASTDCGTLQSRLI 367
L + ++V +GEE E V + + ++K W ERG G +++ R++
Sbjct: 1341 LPDLVEVSSGEENEQVVFSHRAEFYRYDKDVGQWKERGIGDIKILQNYDNK----HVRIL 1396
Query: 368 MRNQGSLRLILNSKLWAQMKIQ---------------------RANHKNVRITATDLEDY 406
MR L+L N ++ M +Q + H VR D+ D
Sbjct: 1397 MRRDQVLKLCANHRITPDMSLQNMKGTERVWVWTACDFADGERKVEHLAVRFKLQDVADS 1456
Query: 407 SIKIFLIQASAQDTAYLYAAIHHR-------------LVALQSFNKQR-DVNQAESLSET 452
KIF +AQ+ L R + L+ ++R DV Q + +++
Sbjct: 1457 FKKIFDEAKTAQEKDSLITPHVSRSSTPRESPCGKIAVAVLEETTRERTDVIQGDDVADA 1516
Query: 453 AQQLNCESCDE 463
A ++ S E
Sbjct: 1517 ASEVEVSSTSE 1527
>gi|169162953 PREDICTED: RANBP2-like and GRIP domain containing 8
[Homo sapiens]
Length = 1765
Score = 47.4 bits (111), Expect = 3e-05
Identities = 74/334 (22%), Positives = 136/334 (40%), Gaps = 30/334 (8%)
Query: 138 QGPVKHSKHVIRPAILQLPQARSCAKVRKTFGHKALESCKTKEKTNNKIS-EGNSYLLSE 196
Q P +S++++RPA A V T G E TKE + +S +G + +SE
Sbjct: 879 QSPAYNSQYLLRPA----------ANVTPTKGSSNTEFKSTKEGFSIPVSADGFKFGISE 928
Query: 197 NLSRARISVQLSTNQDFLGATSVGCQPNEDKCSFKSCSSNFVFGENMVERVLGTQKLTQP 256
++ + + N L A + + F SS F F + + +
Sbjct: 929 PGNQEKKREKPLENDTGLQAQDIRGRKKGRGVIFGQTSSTFTFADVAKSTSGEGFQFGKK 988
Query: 257 QLENDSY--AKEKPFKSIPKFPVNFLSSRTDSIKNTSLI--ESAAAFSSQPSRKCLLEKI 312
L + A EK F S N ++ D K+ E + +P + + EK+
Sbjct: 989 DLNFKGFSGAGEKLFSSRYGKMANKANTSGDFEKDDDAYKTEDSDDIHFEPVVQ-MPEKV 1047
Query: 313 DVITGEETEHNVLKINCKLFIFNKTTQSWIERGRGTLRLNDTASTDCGTLQSRLIMRNQG 372
+++TGEE E + KLF F+ + W ERG G L++ + R++MR +
Sbjct: 1048 ELVTGEEGEKVLYSQGVKLFRFDAEVRQWKERGLGNLKILKNEVNG----KLRMLMRREQ 1103
Query: 373 SLRLILNSKLWAQMKIQ--RANHKNVRITATDLEDYSIKIFLIQAS------AQDTAYLY 424
L++ N + M ++ + + +A+D D K+ + A A++ +
Sbjct: 1104 VLKVCANHWITTTMNLKPLSGSDRAWMWSASDFSDGDAKLERLAAKFKTPELAEEFKQKF 1163
Query: 425 AAIHHRL--VALQSFNKQRDVNQAESLSETAQQL 456
L + LQ+ +K D +A L + A+++
Sbjct: 1164 EECQRLLLDIPLQTPHKLVDTGRAAKLIQRAEEM 1197
Score = 44.3 bits (103), Expect = 3e-04
Identities = 42/191 (21%), Positives = 74/191 (38%), Gaps = 39/191 (20%)
Query: 308 LLEKIDVITGEETEHNVLKINCKLFIFNKTTQSWIERGRGTLRLNDTASTDCGTLQSRLI 367
L + ++V +GEE E V +++ ++K W ERG G +++ Q R++
Sbjct: 1340 LPDLVEVSSGEENEQVVFSHRAEIYRYDKDVGQWKERGIGDIKILQNYDNK----QVRIV 1395
Query: 368 MRNQGSLRLILNSKLWAQMKIQ---------------------RANHKNVRITATDLEDY 406
MR L+L N ++ M +Q + H VR D+ D
Sbjct: 1396 MRRDQVLKLCANHRITPDMSLQNMKGTERVWVWTACDFADGERKVEHLAVRFKLQDVADS 1455
Query: 407 SIKIFLIQASAQDTAYLYAAIHHR-------------LVALQSFNKQR-DVNQAESLSET 452
KIF +AQ+ L R + L+ ++R DV Q + +++
Sbjct: 1456 FKKIFDEAKTAQEKDSLITPHVSRSSTPRESPCGKIAVAVLEEITRERTDVIQGDDVADA 1515
Query: 453 AQQLNCESCDE 463
A ++ S E
Sbjct: 1516 ASEVEVSSTSE 1526
Score = 32.7 bits (73), Expect = 0.77
Identities = 30/108 (27%), Positives = 44/108 (40%), Gaps = 20/108 (18%)
Query: 49 FKRPAEDTLYEAAEPE----CNGFPTKRVRSSSFTFHITDSQSQGVSTL--------SQK 96
F R AED +A PE C + TK + + I D +S + S K
Sbjct: 687 FHRKAEDIENDALSPEEQEECRNYLTK---TRDYLIKIIDDGDSNLSVVKKLPVPLESVK 743
Query: 97 QMRCSSVTNLPTFPHSGPVRKNNVFMTSALVQSSVDIKSAEQGPVKHS 144
QM S + L + GP+ KN +L + +IK + P K+S
Sbjct: 744 QMLNSVMQELEDYSEGGPLYKN-----GSLRNADSEIKHSTPSPTKYS 786
>gi|83267877 RANBP2-like and GRIP domain containing 5 isoform 1 [Homo
sapiens]
Length = 1765
Score = 46.6 bits (109), Expect = 5e-05
Identities = 73/334 (21%), Positives = 135/334 (40%), Gaps = 30/334 (8%)
Query: 138 QGPVKHSKHVIRPAILQLPQARSCAKVRKTFGHKALESCKTKEKTNNKIS-EGNSYLLSE 196
Q P +S++++RPA A V T G E TKE + +S +G + +SE
Sbjct: 879 QSPAYNSQYLLRPA----------ANVTPTKGSSNTEFKSTKEGFSIPVSADGFKFGISE 928
Query: 197 NLSRARISVQLSTNQDFLGATSVGCQPNEDKCSFKSCSSNFVFGENMVERVLGTQKLTQP 256
++ + + N A + + F SS F F + + +
Sbjct: 929 PGNQEKKREKPLENDTGFQAQDISGRKKGRGVIFGQTSSTFTFADVAKSTSGEGFQFGKK 988
Query: 257 QLENDSY--AKEKPFKSIPKFPVNFLSSRTDSIKNTSLI--ESAAAFSSQPSRKCLLEKI 312
L + A EK F S N ++ D K+ E + +P + + EK+
Sbjct: 989 DLNFKGFSGAGEKLFSSRYGKMANKANTSGDFEKDDDAYKTEDSDDIHFEPVVQ-MPEKV 1047
Query: 313 DVITGEETEHNVLKINCKLFIFNKTTQSWIERGRGTLRLNDTASTDCGTLQSRLIMRNQG 372
+++TGEE E + KLF F+ + W ERG G L++ + R++MR +
Sbjct: 1048 ELVTGEEGEKVLYSQGVKLFRFDAEVRQWKERGLGNLKILKNEVNG----KLRMLMRREQ 1103
Query: 373 SLRLILNSKLWAQMKIQ--RANHKNVRITATDLEDYSIKIFLIQAS------AQDTAYLY 424
L++ N + M ++ + + +A+D D K+ + A A++ +
Sbjct: 1104 VLKVCANHWITTTMNLKPLSGSDRAWMWSASDFSDGDAKLERLAAKFKTPELAEEFKQKF 1163
Query: 425 AAIHHRL--VALQSFNKQRDVNQAESLSETAQQL 456
L + LQ+ +K D +A L + A+++
Sbjct: 1164 EECQRLLLDIPLQTPHKLVDTGRAAKLIQRAEEM 1197
Score = 43.1 bits (100), Expect = 6e-04
Identities = 42/191 (21%), Positives = 74/191 (38%), Gaps = 39/191 (20%)
Query: 308 LLEKIDVITGEETEHNVLKINCKLFIFNKTTQSWIERGRGTLRLNDTASTDCGTLQSRLI 367
L + ++V +GEE E V +++ ++K W ERG G +++ Q R++
Sbjct: 1340 LPDLVEVSSGEENEQVVFSHRAEIYRYDKDVGQWKERGIGDIKILQNYDNK----QVRIV 1395
Query: 368 MRNQGSLRLILNSKLWAQMKIQ---------------------RANHKNVRITATDLEDY 406
MR L+L N ++ M +Q + H VR D+ D
Sbjct: 1396 MRRDQVLKLCANHRITPDMSLQNMKGTERVWVWTACDFADGERKVEHLAVRFKLQDVADS 1455
Query: 407 SIKIFLIQASAQDTAYLYAAIHHR-------------LVALQSFNKQR-DVNQAESLSET 452
KIF +AQ+ L R + L+ ++R DV Q + +++
Sbjct: 1456 FKKIFDEAKTAQEKDSLITPHVSRSSTPRESPCGKIAVAILEETTRERTDVIQGDDVADA 1515
Query: 453 AQQLNCESCDE 463
A ++ S E
Sbjct: 1516 ASEVEVSSTSE 1526
Score = 32.7 bits (73), Expect = 0.77
Identities = 30/108 (27%), Positives = 44/108 (40%), Gaps = 20/108 (18%)
Query: 49 FKRPAEDTLYEAAEPE----CNGFPTKRVRSSSFTFHITDSQSQGVSTL--------SQK 96
F R AED +A PE C + TK + + I D +S + S K
Sbjct: 687 FHRKAEDIENDALSPEEQEECRNYLTK---TRDYLIKIIDDGDSNLSVVKKLPVPLESVK 743
Query: 97 QMRCSSVTNLPTFPHSGPVRKNNVFMTSALVQSSVDIKSAEQGPVKHS 144
QM S + L + GP+ KN +L + +IK + P K+S
Sbjct: 744 QMLNSVMQELEDYSEGGPLYKN-----GSLRNADSEIKHSTPSPTKYS 786
>gi|182765478 RANBP2-like and GRIP domain containing 6 [Homo sapiens]
Length = 1765
Score = 46.6 bits (109), Expect = 5e-05
Identities = 73/334 (21%), Positives = 135/334 (40%), Gaps = 30/334 (8%)
Query: 138 QGPVKHSKHVIRPAILQLPQARSCAKVRKTFGHKALESCKTKEKTNNKIS-EGNSYLLSE 196
Q P +S++++RPA A V T G E TKE + +S +G + +SE
Sbjct: 879 QSPAYNSQYLLRPA----------ANVTPTKGSSNTEFKSTKEGFSIPVSADGFKFGISE 928
Query: 197 NLSRARISVQLSTNQDFLGATSVGCQPNEDKCSFKSCSSNFVFGENMVERVLGTQKLTQP 256
++ + + N A + + F SS F F + + +
Sbjct: 929 PGNQEKKREKPLENDTGFQAQDISGRKKGRGVIFGQTSSTFTFADVAKSTSGEGFQFGKK 988
Query: 257 QLENDSY--AKEKPFKSIPKFPVNFLSSRTDSIKNTSLI--ESAAAFSSQPSRKCLLEKI 312
L + A EK F S N ++ D K+ E + +P + + EK+
Sbjct: 989 DLNFKGFSGAGEKLFSSRYGKMANKANTSGDFEKDDDAYKTEDSDDIHFEPVVQ-MPEKV 1047
Query: 313 DVITGEETEHNVLKINCKLFIFNKTTQSWIERGRGTLRLNDTASTDCGTLQSRLIMRNQG 372
+++TGEE E + KLF F+ + W ERG G L++ + R++MR +
Sbjct: 1048 ELVTGEEGEKVLYSQGVKLFRFDAEVRQWKERGLGNLKILKNEVNG----KLRMLMRREQ 1103
Query: 373 SLRLILNSKLWAQMKIQ--RANHKNVRITATDLEDYSIKIFLIQAS------AQDTAYLY 424
L++ N + M ++ + + +A+D D K+ + A A++ +
Sbjct: 1104 VLKVCANHWITTTMNLKPLSGSDRAWMWSASDFSDGDAKLERLAAKFKTPELAEEFKQKF 1163
Query: 425 AAIHHRL--VALQSFNKQRDVNQAESLSETAQQL 456
L + LQ+ +K D +A L + A+++
Sbjct: 1164 EECQRLLLDIPLQTPHKLVDTGRAAKLIQRAEEM 1197
Score = 43.1 bits (100), Expect = 6e-04
Identities = 42/191 (21%), Positives = 74/191 (38%), Gaps = 39/191 (20%)
Query: 308 LLEKIDVITGEETEHNVLKINCKLFIFNKTTQSWIERGRGTLRLNDTASTDCGTLQSRLI 367
L + ++V +GEE E V +++ ++K W ERG G +++ Q R++
Sbjct: 1340 LPDLVEVSSGEENEQVVFSHRAEIYRYDKDVGQWKERGIGDIKILQNYDNK----QVRIV 1395
Query: 368 MRNQGSLRLILNSKLWAQMKIQ---------------------RANHKNVRITATDLEDY 406
MR L+L N ++ M +Q + H VR D+ D
Sbjct: 1396 MRRDQVLKLCANHRITPDMSLQNMKGTERVWVWTACDFADGERKVEHLAVRFKLQDVADS 1455
Query: 407 SIKIFLIQASAQDTAYLYAAIHHR-------------LVALQSFNKQR-DVNQAESLSET 452
KIF +AQ+ L R + L+ ++R DV Q + +++
Sbjct: 1456 FKKIFDEAKTAQEKDSLITPHVSRSSTPRESPCGKIAVAILEETTRERTDVIQGDDVADA 1515
Query: 453 AQQLNCESCDE 463
A ++ S E
Sbjct: 1516 ASEVEVSSTSE 1526
Score = 32.7 bits (73), Expect = 0.77
Identities = 30/108 (27%), Positives = 44/108 (40%), Gaps = 20/108 (18%)
Query: 49 FKRPAEDTLYEAAEPE----CNGFPTKRVRSSSFTFHITDSQSQGVSTL--------SQK 96
F R AED +A PE C + TK + + I D +S + S K
Sbjct: 687 FHRKAEDIENDALSPEEQEECRNYLTK---TRDYLIKIIDDGDSNLSVVKKLPVPLESVK 743
Query: 97 QMRCSSVTNLPTFPHSGPVRKNNVFMTSALVQSSVDIKSAEQGPVKHS 144
QM S + L + GP+ KN +L + +IK + P K+S
Sbjct: 744 QMLNSVMQELEDYSEGGPLYKN-----GSLRNADSEIKHSTPSPTKYS 786
>gi|150418007 RAN binding protein 2 [Homo sapiens]
Length = 3224
Score = 45.1 bits (105), Expect = 1e-04
Identities = 69/304 (22%), Positives = 123/304 (40%), Gaps = 22/304 (7%)
Query: 169 GHKALESCKTKEKTNNKIS-EGNSYLLSENLSRARISVQLSTNQDFLGATSVGCQPNEDK 227
G E TKE + +S +G + +SE ++ + S + N A + Q N
Sbjct: 1876 GSSNTEFKSTKEGFSIPVSADGFKFGISEPGNQEKKSEKPLENGTGFQAQDISGQKNGRG 1935
Query: 228 CSFKSCSSNFVFGENMVERVLGTQ---KLTQPQLENDSYAKEKPFKSIPKFPVNFLSSRT 284
F SS F F + + + G P + S A EK F S N ++
Sbjct: 1936 VIFGQTSSTFTFAD-LAKSTSGEGFQFGKKDPNFKGFSGAGEKLFSSQYGKMANKANTSG 1994
Query: 285 DSIKNTSLI--ESAAAFSSQPSRKCLLEKIDVITGEETEHNVLKINCKLFIFNKTTQSWI 342
D K+ E + +P + + EK++++TGEE E + KLF F+ W
Sbjct: 1995 DFEKDDDAYKTEDSDDIHFEPVVQ-MPEKVELVTGEEDEKVLYSQRVKLFRFDAEVSQWK 2053
Query: 343 ERGRGTLRLNDTASTDCGTLQSRLIMRNQGSLRLILNSKLWAQMKIQ--RANHKNVRITA 400
ERG G L++ + R++MR + L++ N + M ++ + + A
Sbjct: 2054 ERGLGNLKILKNEVNG----KLRMLMRREQVLKVCANHWITTTMNLKPLSGSDRAWMWLA 2109
Query: 401 TDLEDYSIKIFLIQAS------AQDTAYLYAAIHHRL--VALQSFNKQRDVNQAESLSET 452
+D D K+ + A A++ + L + LQ+ +K D +A L +
Sbjct: 2110 SDFSDGDAKLEQLAAKFKTPELAEEFKQKFEECQRLLLDIPLQTPHKLVDTGRAAKLIQR 2169
Query: 453 AQQL 456
A+++
Sbjct: 2170 AEEM 2173
Score = 44.3 bits (103), Expect = 3e-04
Identities = 39/155 (25%), Positives = 64/155 (41%), Gaps = 10/155 (6%)
Query: 308 LLEKIDVITGEETEHNVLKINCKLFIFNKTTQSWIERGRGTLRLNDTASTDCGTLQSRLI 367
L + ++V +GEE E V KL+ ++K W ERG G +++ Q R++
Sbjct: 2316 LPDLVEVSSGEENEQVVFSHRAKLYRYDKDVGQWKERGIGDIKILQNYDNK----QVRIV 2371
Query: 368 MRNQGSLRLILNSKLWAQMKIQ--RANHKNVRITATDLEDYSIKI--FLIQASAQDTAYL 423
MR L+L N ++ M +Q + + TA D D K+ ++ QD A
Sbjct: 2372 MRRDQVLKLCANHRITPDMTLQNMKGTERVWLWTACDFADGERKVEHLAVRFKLQDVADS 2431
Query: 424 YAAIHHRLVALQSFNKQRDVNQAESLSETAQQLNC 458
+ I Q K + S S T ++ C
Sbjct: 2432 FKKIFDEAKTAQ--EKDSLITPHVSRSSTPRESPC 2464
Score = 42.4 bits (98), Expect = 0.001
Identities = 26/81 (32%), Positives = 43/81 (53%), Gaps = 4/81 (4%)
Query: 308 LLEKIDVITGEETEHNVLKINCKLFIFNKTTQSWIERGRGTLRLNDTASTDCGTLQSRLI 367
L +KI+V TGEE E KLF F+ ++ W ERG G +++ ++ + RL+
Sbjct: 1178 LPDKIEVKTGEEDEEEFFCNRAKLFRFDVESKEWKERGIGNVKILRHKTSG----KIRLL 1233
Query: 368 MRNQGSLRLILNSKLWAQMKI 388
MR + L++ N + MK+
Sbjct: 1234 MRREQVLKICANHYISPDMKL 1254
Score = 38.5 bits (88), Expect = 0.014
Identities = 26/104 (25%), Positives = 50/104 (48%), Gaps = 6/104 (5%)
Query: 309 LEKIDVITGEETEHNVLKINCKLFIFNKTTQSWIERGRGTLRLNDTASTDCGTLQSRLIM 368
L +++V +GEE E + K KL+ +++ W ERG G +++ + R++M
Sbjct: 2918 LPEVEVKSGEEDEEILFKERAKLYRWDRDVSQWKERGVGDIKILWHTMKN----YYRILM 2973
Query: 369 RNQGSLRLILNSKLWAQMKIQRANHKNVRI--TATDLEDYSIKI 410
R ++ N + M+++ N N + TA+D D K+
Sbjct: 2974 RRDQVFKVCANHVITKTMELKPLNVSNNALVWTASDYADGEAKV 3017
>gi|4506407 RAN binding protein 1 [Homo sapiens]
Length = 201
Score = 33.9 bits (76), Expect = 0.34
Identities = 24/83 (28%), Positives = 41/83 (49%), Gaps = 6/83 (7%)
Query: 309 LEKIDVITGEETEHNVLKINCKLFIF--NKTTQSWIERGRGTLRLNDTASTDCGTLQSRL 366
L + ++ T EE E + K+ KLF F W ERG G ++L + G + RL
Sbjct: 33 LPEQEIKTLEEDEEELFKMRAKLFRFASENDLPEWKERGTGDVKL--LKHKEKGAI--RL 88
Query: 367 IMRNQGSLRLILNSKLWAQMKIQ 389
+MR +L++ N + M+++
Sbjct: 89 LMRRDKTLKICANHYITPMMELK 111
>gi|19923191 minichromosome maintenance complex component 3
associated protein [Homo sapiens]
Length = 1980
Score = 33.5 bits (75), Expect = 0.45
Identities = 39/139 (28%), Positives = 59/139 (42%), Gaps = 19/139 (13%)
Query: 42 FEKGEQTFKRPAEDTLYEA-----AEPECNGFPTKRVRSSSFTF-HITDSQSQGVSTLSQ 95
F K E +FK P E+ +++ +EPE ++ S FTF H S G++ S
Sbjct: 139 FGKTEFSFK-PLENAVFKPILGAESEPEKT---QSQIASGFFTFSHPISSAPGGLAPFSF 194
Query: 96 KQMRCSSVTNLPTFPHSGPVRKNNVFMTSALVQSSVDIKSAEQGPV--------KHSKHV 147
Q+ SS T F S PV NN S+ +++ ++GP S
Sbjct: 195 PQVTSSSATT-SNFTFSKPVSSNNSLSAFTPALSNQNVEEEKRGPKSIFGSSNNSFSSFP 253
Query: 148 IRPAILQLPQARSCAKVRK 166
+ A+L P S A VR+
Sbjct: 254 VSSAVLGEPFQASKAGVRQ 272
>gi|61743980 stabilin 2 precursor [Homo sapiens]
Length = 2551
Score = 33.1 bits (74), Expect = 0.59
Identities = 47/191 (24%), Positives = 73/191 (38%), Gaps = 20/191 (10%)
Query: 269 FKSIPKFPVNFLSSRTDSIKNTSLIESAAAFSSQ-----PSRKCLLEKIDVITGEETEHN 323
F S+ F L+ S + + +E S + P L E + ++G + EH+
Sbjct: 2321 FPSLTNFLTEVLAYSNSSARGRAFLEHLTDLSIRGTLFVPQNSGLGEN-ETLSGRDIEHH 2379
Query: 324 VLKINCKLFIFNKTTQSWIERGRGTLRLNDTASTDCGTLQSRLIMRNQGSLRLILNSKLW 383
+ N +F +N + R +L TAS D LQ G R IL ++
Sbjct: 2380 LA--NVSMFFYNDLVNGTTLQTRLGSKLLITASQD--PLQPTETRFVDG--RAILQWDIF 2433
Query: 384 AQMKI-------QRANHKNVRITATDL-EDYSIKIFLIQASAQDTAYLYAAIHHRLVALQ 435
A I +A V +T T L I L+ + AY Y I+ R + Q
Sbjct: 2434 ASNGIIHVISRPLKAPPAPVTLTHTGLGAGIFFAIILVTGAVALAAYSYFRINRRTIGFQ 2493
Query: 436 SFNKQRDVNQA 446
F + D+N A
Sbjct: 2494 HFESEEDINVA 2504
>gi|14149991 RANBP2-like and GRIP domain containing 5 isoform 2
[Homo sapiens]
Length = 904
Score = 32.7 bits (73), Expect = 0.77
Identities = 30/108 (27%), Positives = 44/108 (40%), Gaps = 20/108 (18%)
Query: 49 FKRPAEDTLYEAAEPE----CNGFPTKRVRSSSFTFHITDSQSQGVSTL--------SQK 96
F R AED +A PE C + TK + + I D +S + S K
Sbjct: 687 FHRKAEDIENDALSPEEQEECRNYLTK---TRDYLIKIIDDGDSNLSVVKKLPVPLESVK 743
Query: 97 QMRCSSVTNLPTFPHSGPVRKNNVFMTSALVQSSVDIKSAEQGPVKHS 144
QM S + L + GP+ KN +L + +IK + P K+S
Sbjct: 744 QMLNSVMQELEDYSEGGPLYKN-----GSLRNADSEIKHSTPSPTKYS 786
>gi|118197270 RANBP2-like and GRIP domain containing 7 [Homo
sapiens]
Length = 904
Score = 32.7 bits (73), Expect = 0.77
Identities = 30/108 (27%), Positives = 44/108 (40%), Gaps = 20/108 (18%)
Query: 49 FKRPAEDTLYEAAEPE----CNGFPTKRVRSSSFTFHITDSQSQGVSTL--------SQK 96
F R AED +A PE C + TK + + I D +S + S K
Sbjct: 687 FHRKAEDIENDALSPEEQEECRNYLTK---TRDYLIKIIDDGDSNLSVVKKLPVPLESVK 743
Query: 97 QMRCSSVTNLPTFPHSGPVRKNNVFMTSALVQSSVDIKSAEQGPVKHS 144
QM S + L + GP+ KN +L + +IK + P K+S
Sbjct: 744 QMLNSVMQELEDYSEGGPLYKN-----GSLRNADSEIKHSTPSPTKYS 786
>gi|4507575 tumor necrosis factor receptor 1 precursor [Homo
sapiens]
Length = 455
Score = 31.6 bits (70), Expect = 1.7
Identities = 35/136 (25%), Positives = 54/136 (39%), Gaps = 21/136 (15%)
Query: 132 DIKSAEQGPVKHSKHVIRPAILQLPQARSCAKVRKTFGHKALESCKTKEKTNNKISEGN- 190
D + E G S++ +R + SC+K RK G + SC T +
Sbjct: 80 DCRECESGSFTASENHLRHCL-------SCSKCRKEMGQVEISSCTVDRDTVCGCRKNQY 132
Query: 191 SYLLSENLSRARISVQLSTNQDFLGATSVGCQPNEDKCSFKSCSSNFVFGEN------MV 244
+ SENL + + L N G + CQ E + + +C + F EN
Sbjct: 133 RHYWSENLFQC-FNCSLCLN----GTVHLSCQ--EKQNTVCTCHAGFFLRENECVSCSNC 185
Query: 245 ERVLGTQKLTQPQLEN 260
++ L KL PQ+EN
Sbjct: 186 KKSLECTKLCLPQIEN 201
>gi|24497447 nucleoporin 50kDa isoform a [Homo sapiens]
Length = 440
Score = 31.6 bits (70), Expect = 1.7
Identities = 49/186 (26%), Positives = 76/186 (40%), Gaps = 18/186 (9%)
Query: 219 VGCQPNEDKCSFKSCSSNFVFGENMVERVLGTQKLTQPQLENDSYAKEKPFKSIPKFPVN 278
V + D S + S++F FG+ + VLG+ L+ L S++ P S
Sbjct: 225 VASEKKTDPSSLGATSASFNFGKKVDSSVLGS--LSSVPLTGFSFS---PGNSSLFGKDT 279
Query: 279 FLSSRTDSIKNTSLIESAAAFSSQPSRKCLLEKID-----VITGEETEHNVLKINCKLFI 333
S S T +E A S + E+ D V+T + E CKLF
Sbjct: 280 TQSKPVSSPFPTKPLEGQAEGDSGECKGGDEEENDEPPKVVVTEVKEEDAFYSKKCKLFY 339
Query: 334 FNKTTQSWIERGRGTLRLNDTASTDCGTLQSRLIMRNQGSL-RLILNSKLWAQMKIQRAN 392
K + E+G GTL L TA+ +++L++R +L ++LN + M R
Sbjct: 340 --KKDNEFKEKGIGTLHLKPTANQ-----KTQLLVRADTNLGNILLNVLIPPNMPCTRTG 392
Query: 393 HKNVRI 398
NV I
Sbjct: 393 KNNVLI 398
>gi|24497451 nucleoporin 50kDa isoform b [Homo sapiens]
Length = 468
Score = 31.6 bits (70), Expect = 1.7
Identities = 49/186 (26%), Positives = 76/186 (40%), Gaps = 18/186 (9%)
Query: 219 VGCQPNEDKCSFKSCSSNFVFGENMVERVLGTQKLTQPQLENDSYAKEKPFKSIPKFPVN 278
V + D S + S++F FG+ + VLG+ L+ L S++ P S
Sbjct: 253 VASEKKTDPSSLGATSASFNFGKKVDSSVLGS--LSSVPLTGFSFS---PGNSSLFGKDT 307
Query: 279 FLSSRTDSIKNTSLIESAAAFSSQPSRKCLLEKID-----VITGEETEHNVLKINCKLFI 333
S S T +E A S + E+ D V+T + E CKLF
Sbjct: 308 TQSKPVSSPFPTKPLEGQAEGDSGECKGGDEEENDEPPKVVVTEVKEEDAFYSKKCKLFY 367
Query: 334 FNKTTQSWIERGRGTLRLNDTASTDCGTLQSRLIMRNQGSL-RLILNSKLWAQMKIQRAN 392
K + E+G GTL L TA+ +++L++R +L ++LN + M R
Sbjct: 368 --KKDNEFKEKGIGTLHLKPTANQ-----KTQLLVRADTNLGNILLNVLIPPNMPCTRTG 420
Query: 393 HKNVRI 398
NV I
Sbjct: 421 KNNVLI 426
>gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1363
Score = 29.6 bits (65), Expect = 6.5
Identities = 37/175 (21%), Positives = 72/175 (41%), Gaps = 23/175 (13%)
Query: 132 DIKSAEQGPVKHSKHVIRPAILQLPQARSCAKVRKTFGHKALESCKTKEKTNNKISEGNS 191
D++S +Q ++H +++ + Q + K K + K K++ +E N
Sbjct: 343 DLRSIQQQILEHKNKMLKNHLRNDNQETAAMKPENLKKRKKRK--KLKKRKEGAKAEHNL 400
Query: 192 YLLSENLSRARISVQLSTNQDFLGATSVGCQPNEDKCSFKSCSSNFVFGENMVERVLGTQ 251
+ SE ++ S N+ + S G + +E +FG M++R +
Sbjct: 401 KVASEEKQER---LERSENKQPQDSQSYGKKKDE------------MFGNFMLKRDIAML 445
Query: 252 KLTQPQLENDSYAKEKPF----KSIPKFPVNFLSSRTDSIKNTSLIESAAAFSSQ 302
K ++NDS KEK + KSI + NF ++ + + + A +S Q
Sbjct: 446 KEELYAIKNDSLRKEKKYIQEIKSITEINANF--EKSVRLNEEMITKKVAQYSQQ 498
>gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1366
Score = 29.6 bits (65), Expect = 6.5
Identities = 37/175 (21%), Positives = 72/175 (41%), Gaps = 23/175 (13%)
Query: 132 DIKSAEQGPVKHSKHVIRPAILQLPQARSCAKVRKTFGHKALESCKTKEKTNNKISEGNS 191
D++S +Q ++H +++ + Q + K K + K K++ +E N
Sbjct: 372 DLRSIQQQILEHKNKMLKNHLRNDNQETAAMKPENLKKRKKRK--KLKKRKEGAKAEHNL 429
Query: 192 YLLSENLSRARISVQLSTNQDFLGATSVGCQPNEDKCSFKSCSSNFVFGENMVERVLGTQ 251
+ SE ++ S N+ + S G + +E +FG M++R +
Sbjct: 430 KVASEEKQER---LERSENKQPQDSQSYGKKKDE------------MFGNFMLKRDIAML 474
Query: 252 KLTQPQLENDSYAKEKPF----KSIPKFPVNFLSSRTDSIKNTSLIESAAAFSSQ 302
K ++NDS KEK + KSI + NF ++ + + + A +S Q
Sbjct: 475 KEELYAIKNDSLRKEKKYIQEIKSITEINANF--EKSVRLNEEMITKKVAQYSQQ 527
>gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1139
Score = 29.6 bits (65), Expect = 6.5
Identities = 37/175 (21%), Positives = 72/175 (41%), Gaps = 23/175 (13%)
Query: 132 DIKSAEQGPVKHSKHVIRPAILQLPQARSCAKVRKTFGHKALESCKTKEKTNNKISEGNS 191
D++S +Q ++H +++ + Q + K K + K K++ +E N
Sbjct: 372 DLRSIQQQILEHKNKMLKNHLRNDNQETAAMKPENLKKRKKRK--KLKKRKEGAKAEHNL 429
Query: 192 YLLSENLSRARISVQLSTNQDFLGATSVGCQPNEDKCSFKSCSSNFVFGENMVERVLGTQ 251
+ SE ++ S N+ + S G + +E +FG M++R +
Sbjct: 430 KVASEEKQER---LERSENKQPQDSQSYGKKKDE------------MFGNFMLKRDIAML 474
Query: 252 KLTQPQLENDSYAKEKPF----KSIPKFPVNFLSSRTDSIKNTSLIESAAAFSSQ 302
K ++NDS KEK + KSI + NF ++ + + + A +S Q
Sbjct: 475 KEELYAIKNDSLRKEKKYIQEIKSITEINANF--EKSVRLNEEMITKKVAQYSQQ 527
>gi|203096856 kinesin family member 7 [Homo sapiens]
Length = 1343
Score = 29.6 bits (65), Expect = 6.5
Identities = 25/74 (33%), Positives = 38/74 (51%), Gaps = 4/74 (5%)
Query: 6 RKGSSHLPGSLHTCKLKLQEDRR---QQEKSVIAQPIFVFEKGEQTFKRPAEDTLYEAAE 62
R GS+ SL + K++E ++ Q+ + V+ Q + E GE+ KR A EA
Sbjct: 892 RSGSNGSVVSLEQ-QQKIEEQKKWLDQEMEKVLQQRRALEELGEELHKREAILAKKEALM 950
Query: 63 PECNGFPTKRVRSS 76
E G +KR+RSS
Sbjct: 951 QEKTGLESKRLRSS 964
>gi|7019499 peroxisome proliferator-activated receptor gamma,
coactivator 1 alpha [Homo sapiens]
Length = 798
Score = 29.3 bits (64), Expect = 8.5
Identities = 41/192 (21%), Positives = 65/192 (33%), Gaps = 23/192 (11%)
Query: 154 QLPQARSCAKVRKTFGHKALESCKTKEKTNNKISEGNSYLLSENLSRARISVQLSTNQDF 213
Q PQ R C+++ K + + T N+ S + + S L
Sbjct: 200 QKPQRRPCSELLKYLTTN--DDPPHTKPTENRNSSRDKCTSKKKSHTQSQSQHLQAKPTT 257
Query: 214 LGATSVGCQPNEDKCSFKSCSSNFVFGENMVERVL-----GTQKLTQPQLENDSYAKEKP 268
L PN+ K S F +ER L GT LT P ++ P
Sbjct: 258 LSLPLTPESPNDPKGS--------PFENKTIERTLSVELSGTAGLTPPTTPPHKANQDNP 309
Query: 269 FKSIPKFPVNFLSSRTDSIKNTSLIESAAAFSSQPSRK--------CLLEKIDVITGEET 320
F++ PK + + K ES+ + ++K L K V+TG
Sbjct: 310 FRASPKLKSSCKTVVPPPSKKPRYSESSGTQGNNSTKKGPEQSELYAQLSKSSVLTGGHE 369
Query: 321 EHNVLKINCKLF 332
E + + +LF
Sbjct: 370 ERKTKRPSLRLF 381
>gi|217416354 sphingosine kinase type 1-interacting protein isoform
1 [Homo sapiens]
Length = 1700
Score = 29.3 bits (64), Expect = 8.5
Identities = 23/110 (20%), Positives = 46/110 (41%), Gaps = 3/110 (2%)
Query: 152 ILQLPQARSCAKVRKTFGHKALESCKTKEKTNNKISEGNSYLLSENLSRARISVQLSTNQ 211
+L+ Q R C G+ ++ +CK K +N + E Y L +I ++
Sbjct: 21 VLEPQQGRGCGSSGSGPGN-SITACK-KVLRSNSLLESTDYWLQNQRMPCQIGFVEDKSE 78
Query: 212 DFLGATSVGCQPNEDKCSFKSCSSNFVFGENMVERVLGTQKLTQPQLEND 261
+ V N+D+CS + V + +++ + + QP+ EN+
Sbjct: 79 NCASVCFVNLDVNKDECSTEHLQQKLVNVSPDLPKLISSMNVQQPK-ENE 127
>gi|217416352 sphingosine kinase type 1-interacting protein isoform
2 [Homo sapiens]
Length = 1671
Score = 29.3 bits (64), Expect = 8.5
Identities = 23/110 (20%), Positives = 46/110 (41%), Gaps = 3/110 (2%)
Query: 152 ILQLPQARSCAKVRKTFGHKALESCKTKEKTNNKISEGNSYLLSENLSRARISVQLSTNQ 211
+L+ Q R C G+ ++ +CK K +N + E Y L +I ++
Sbjct: 21 VLEPQQGRGCGSSGSGPGN-SITACK-KVLRSNSLLESTDYWLQNQRMPCQIGFVEDKSE 78
Query: 212 DFLGATSVGCQPNEDKCSFKSCSSNFVFGENMVERVLGTQKLTQPQLEND 261
+ V N+D+CS + V + +++ + + QP+ EN+
Sbjct: 79 NCASVCFVNLDVNKDECSTEHLQQKLVNVSPDLPKLISSMNVQQPK-ENE 127
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.127 0.361
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,625,478
Number of Sequences: 37866
Number of extensions: 714573
Number of successful extensions: 2033
Number of sequences better than 10.0: 28
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 1995
Number of HSP's gapped (non-prelim): 49
length of query: 490
length of database: 18,247,518
effective HSP length: 106
effective length of query: 384
effective length of database: 14,233,722
effective search space: 5465749248
effective search space used: 5465749248
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.