BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapiens] (123 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 242 6e-65 gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 115 8e-27 gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 111 2e-25 gi|221219020 NYD-SP11 protein [Homo sapiens] 91 2e-19 gi|55741709 RNA binding motif protein 25 [Homo sapiens] 89 8e-19 gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 88 2e-18 gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 87 3e-18 gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 87 3e-18 gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 87 4e-18 gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 87 4e-18 gi|148746195 trichohyalin [Homo sapiens] 86 9e-18 gi|239747174 PREDICTED: hypothetical protein XP_002343931, parti... 84 2e-17 gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] 84 3e-17 gi|169167715 PREDICTED: hypothetical protein [Homo sapiens] 80 3e-16 gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo ... 80 5e-16 gi|102467235 inner centromere protein antigens 135/155kDa isofor... 79 7e-16 gi|102467242 inner centromere protein antigens 135/155kDa isofor... 79 7e-16 gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 79 9e-16 gi|239745093 PREDICTED: hypothetical protein XP_002343359 [Homo ... 79 1e-15 gi|27734775 hypothetical protein LOC286499 [Homo sapiens] 78 1e-15 gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 78 2e-15 gi|52426743 cisplatin resistance-associated overexpressed protei... 77 3e-15 gi|19923485 cisplatin resistance-associated overexpressed protei... 77 3e-15 gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 77 3e-15 gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 77 3e-15 gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 77 3e-15 gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 77 3e-15 gi|239750213 PREDICTED: hypothetical protein [Homo sapiens] 77 4e-15 gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 77 4e-15 gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 77 4e-15 >gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapiens] Length = 123 Score = 242 bits (617), Expect = 6e-65 Identities = 123/123 (100%), Positives = 123/123 (100%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT Sbjct: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120 Query: 121 KKK 123 KKK Sbjct: 121 KKK 123 >gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] Length = 245 Score = 115 bits (288), Expect = 8e-27 Identities = 56/130 (43%), Positives = 94/130 (72%), Gaps = 8/130 (6%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 KK+KK +++ EE E + E+E KEG+ KEKRK+K K KE+ + +KE ++R+ KEE ++ Sbjct: 83 KKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEK-KERGRTSKEGKERERKEERKR 141 Query: 61 KRKRKRKKKKEEEEREEEEEEEEE-------EKEEEEKEEGRRRKKKKKRRRKEEEEEKK 113 + +++R++KKEE E+E E +E ++ EKEEE KE+ R+ +KK++R RKE ++E++ Sbjct: 142 EERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERE 201 Query: 114 KKRRRKTKKK 123 +K RR+ KK+ Sbjct: 202 RKERRERKKE 211 Score = 114 bits (284), Expect = 2e-26 Identities = 49/123 (39%), Positives = 92/123 (74%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 +KK++++KE +E EE E+ +++E+KE R K ++R+ KE++K+ + E+ ++KEE EK Sbjct: 97 RKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREK 156 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120 +R+RK +KK+E ++ E+EEE +E++ +E K+ R RK++KK R ++E E+KK+R++K Sbjct: 157 ERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKE 216 Query: 121 KKK 123 ++K Sbjct: 217 ERK 219 Score = 105 bits (263), Expect = 7e-24 Identities = 51/134 (38%), Positives = 93/134 (69%), Gaps = 11/134 (8%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKE---KRKEKEKKKKTKETEKRKEKEE 57 K+K+KKK++ E ++E +E E KE +++E+RKE K++E+EK+++ KE +KR+ K+ Sbjct: 112 KEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQV 171 Query: 58 EEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEE-------- 109 EK+ +RK K++KE ++RE +E ++E+E +E+ E ++ +KKK+ R+KE + Sbjct: 172 GEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWR 231 Query: 110 EEKKKKRRRKTKKK 123 E+++ KR RK +KK Sbjct: 232 EKERGKRERKERKK 245 Score = 105 bits (262), Expect = 9e-24 Identities = 60/142 (42%), Positives = 98/142 (69%), Gaps = 19/142 (13%) Query: 1 KKKKKKKKETEETEETEETEE---EEEKEGKRKEKRKEK---RKEKEKKKKTKETEKRKE 54 +K+ KK++E+E +E E E+ E EKE KR+ +KEK RK++E+++K + EK + Sbjct: 48 RKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENK 107 Query: 55 KEEEEKKRKRKRKKKK-------EEEEREEE---EEEEEEEKEEEEKEEGRRRKKKKKRR 104 + EE++KRK+K KK++ +E ER+EE EE +E E+++EE+E+ R RK++KKR Sbjct: 108 EGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRE 167 Query: 105 RK---EEEEEKKKKRRRKTKKK 123 RK E+EEE+K+K R++ KK+ Sbjct: 168 RKQVGEKEEERKEKERKERKKR 189 Score = 103 bits (258), Expect = 3e-23 Identities = 47/128 (36%), Positives = 92/128 (71%), Gaps = 6/128 (4%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 ++++K+K+E E+ + E ++E++ E K++E+ ++KR+ +++ K+ +E EKRK+KE++E+ Sbjct: 64 REREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKER 123 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRK------EEEEEKKK 114 R K K++E +E + EE +E E+++EE+E+ R RK++KKR RK EE +EK++ Sbjct: 124 GRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKER 183 Query: 115 KRRRKTKK 122 K R+K ++ Sbjct: 184 KERKKRER 191 Score = 96.7 bits (239), Expect = 4e-21 Identities = 47/121 (38%), Positives = 85/121 (70%), Gaps = 6/121 (4%) Query: 7 KKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKR 66 + E E E ET +E +KE R+ +RK++R+E+EK+K+ +E E+++E+ ++EKK +RK+ Sbjct: 35 QSEIREREREIETRKEGKKE--RESERKKERREREKRKREREKERKRERGKKEKKGERKK 92 Query: 67 ----KKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKK 122 +KK+ E+ +E EE+E+ K++E+KE GR K+ K+R RKEE + +++K R + K+ Sbjct: 93 EERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKE 152 Query: 123 K 123 + Sbjct: 153 E 153 Score = 80.1 bits (196), Expect = 4e-16 Identities = 43/115 (37%), Positives = 78/115 (67%), Gaps = 11/115 (9%) Query: 16 TEETEEEEEKEGKRK-EKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEE 74 T+ + E +E +R+ E RKE +KE+E ++K + E+ K K E EK+RKR+R KK+++ E Sbjct: 30 TQPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGE 89 Query: 75 REEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEK------KKKRRRKTKKK 123 R++EE E ++ + E+E +EG ++K++R+K+E++E+ K+R RK ++K Sbjct: 90 RKKEERERKKRRREKENKEG----EEKEKRKKKEKKERGRTSKEGKERERKEERK 140 >gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] Length = 275 Score = 111 bits (277), Expect = 2e-25 Identities = 45/123 (36%), Positives = 94/123 (76%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 ++K+K+++E E E + E+++ K+ +R ++R+ KRKE+EK++K + ++R+++++E+K Sbjct: 43 REKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKK 102 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120 KR+RK++ ++E ++++E +E E E K+ E++ +RRKKK+++ RK E+E K++R+RK Sbjct: 103 KRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKK 162 Query: 121 KKK 123 +KK Sbjct: 163 RKK 165 Score = 110 bits (275), Expect = 3e-25 Identities = 51/129 (39%), Positives = 94/129 (72%), Gaps = 7/129 (5%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61 ++KK+++E E+ + E E + E+ K K+KRK++ + KE+++K KE EK++++ E+++ Sbjct: 35 ERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKER 94 Query: 62 RKRKRKKKKEE------EEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKK- 114 RKRK++KKK E ER++++E +E E+E +++ E +R+K++KK+RRKE + EK++ Sbjct: 95 RKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERG 154 Query: 115 KRRRKTKKK 123 KR RK KK+ Sbjct: 155 KRERKRKKR 163 Score = 108 bits (269), Expect = 1e-24 Identities = 49/120 (40%), Positives = 86/120 (71%), Gaps = 1/120 (0%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 +KK+KKK+E ++ E +++E KE +R+ K++ +RK K+++KK + E+++EKE ++ Sbjct: 97 RKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKR 156 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120 +RKRK+ +KKEE E++ E +E +KE E KE R+K++KK RRK++E +K +K R+T Sbjct: 157 ERKRKK-RKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQT 215 Score = 107 bits (267), Expect = 2e-24 Identities = 46/128 (35%), Positives = 90/128 (70%), Gaps = 5/128 (3%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 +++K+K++E + E E+ + +KE K++E+++ R+E++KKK+ KE E+ ++ E K Sbjct: 75 RERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERK 134 Query: 61 KRKRKRKKKKEEEEREEEEEEEE-----EEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKK 115 ++KR++KK+++E +RE+E + E +KEE EK+ R RK++KK R ++E E+KK+ Sbjct: 135 RKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKE 194 Query: 116 RRRKTKKK 123 R+++ +KK Sbjct: 195 RKKERRKK 202 Score = 103 bits (256), Expect = 4e-23 Identities = 43/131 (32%), Positives = 95/131 (72%), Gaps = 8/131 (6%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 +K++K+++ +E ++ ++ E +E+E KRKE+ K++++ +EK+++ ++ EK+K + ++ Sbjct: 51 EKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRG 110 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEK--------EEEEKEEGRRRKKKKKRRRKEEEEEK 112 +R+RK+KK+++E ERE ++ E + K +E ++E+ R ++++K+++RK+EE EK Sbjct: 111 RRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREK 170 Query: 113 KKKRRRKTKKK 123 K++R RK +KK Sbjct: 171 KRERNRKERKK 181 Score = 99.0 bits (245), Expect = 8e-22 Identities = 46/108 (42%), Positives = 81/108 (75%), Gaps = 2/108 (1%) Query: 18 ETEEEEEKEGKRKEKRK-EKRKEKEKKKKTKETEKRKEKEE-EEKKRKRKRKKKKEEEER 75 + E E +KE + +EKRK E+ KE+++++ KE +KRK++E +E++RKRK ++K+ +E R Sbjct: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90 Query: 76 EEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123 E+E + ++EK++ E+++ RR++KKK+ RKE E E K++R RK KK+ Sbjct: 91 EKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKR 138 Score = 65.1 bits (157), Expect = 1e-11 Identities = 23/78 (29%), Positives = 59/78 (75%) Query: 46 TKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRR 105 +K +R+ + ++E++ + KRK+++E+E + E ++E++++++ E+ + R RK+K++ ++ Sbjct: 26 SKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQ 85 Query: 106 KEEEEEKKKKRRRKTKKK 123 ++E EK++++R+K KKK Sbjct: 86 RKERREKERRKRKKEKKK 103 Score = 53.5 bits (127), Expect = 4e-08 Identities = 24/81 (29%), Positives = 53/81 (65%), Gaps = 9/81 (11%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRK---EKEKKKKTKETEKRKEKEE 57 +K++K++KE + E + ++EE+E KR+ RKE++K KE++ E++KE+++ Sbjct: 144 RKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERR------ERKKERKK 197 Query: 58 EEKKRKRKRKKKKEEEEREEE 78 E +K+K ++K +K + + + + Sbjct: 198 ERRKKKERKKDRKTDRQTDSQ 218 Score = 38.1 bits (87), Expect = 0.002 Identities = 15/56 (26%), Positives = 35/56 (62%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKE 56 KK+++ +KE ++ E +E E +++ K + K+KE++K+++ ++T R +E Sbjct: 170 KKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRE 225 >gi|221219020 NYD-SP11 protein [Homo sapiens] Length = 2873 Score = 91.3 bits (225), Expect = 2e-19 Identities = 50/117 (42%), Positives = 80/117 (68%), Gaps = 5/117 (4%) Query: 6 KKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRK 65 +K+E+ +EE EE EEEEE+E + + +E+RKE+E+ + EK+ EKEEEEKK+K+K Sbjct: 2238 EKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGE-----EKQVEKEEEEKKKKKK 2292 Query: 66 RKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKK 122 KKK+E +E+EE EE+EE EEE E +++++ EEE +++K+ +K K+ Sbjct: 2293 EKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQ 2349 Score = 82.0 bits (201), Expect = 1e-16 Identities = 41/120 (34%), Positives = 78/120 (65%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61 +++++++E EE EE E EEEEE++ + + + K+ KE+E+KKK K+ +K++E +E+E+ Sbjct: 2246 EEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEV 2305 Query: 62 RKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTK 121 + K + EEE +EEEEEE E+E R ++ KK ++ + +E+++K R + + Sbjct: 2306 FEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRRKSLRGRER 2365 Score = 80.5 bits (197), Expect = 3e-16 Identities = 45/123 (36%), Positives = 82/123 (66%), Gaps = 5/123 (4%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 K++ +E EE EE EE EEEE +E +E+RKE+ + +EK+ + +E EK+K+K+E++K Sbjct: 2239 KQESLSSEEEEEREEEEEREEEEVRE--EEEERKEEEEGEEKQVEKEEEEKKKKKKEKKK 2296 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRR---KEEEEEKKKKRR 117 + +++++ EE+E EEE E +EEE+EE +++ R + K+E++ K +++R Sbjct: 2297 EEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQR 2356 Query: 118 RKT 120 RK+ Sbjct: 2357 RKS 2359 Score = 78.6 bits (192), Expect = 1e-15 Identities = 45/121 (37%), Positives = 76/121 (62%), Gaps = 5/121 (4%) Query: 1 KKKKKKKKETEETEETEETEEE--EEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEE 58 ++++++++E E EE E EEE EE+EG+ K+ KE E+EKKKK KE +K + +E+E Sbjct: 2247 EEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKE---EEEKKKKKKEKKKEEVQEKE 2303 Query: 59 EKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRR 118 E +++ +EE E +EEEEEE EE+ + + KK+++ K +E+ +K R R Sbjct: 2304 EVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRRKSLRGR 2363 Query: 119 K 119 + Sbjct: 2364 E 2364 Score = 77.8 bits (190), Expect = 2e-15 Identities = 52/136 (38%), Positives = 78/136 (57%), Gaps = 14/136 (10%) Query: 1 KKKKKKKKETEETEETEETEEEEEKE-----GKRKEKRKE-KRKEKEKKK---KTKETEK 51 ++ K +K +E + EE EE+E +R KRKE KR +K K+K + E E Sbjct: 2163 EESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVES 2222 Query: 52 RKEKEEE-----EKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRK 106 + EE ++ K++ +EEEEREEEEE EEEE EEE+E + ++K+ K Sbjct: 2223 EEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEK 2282 Query: 107 EEEEEKKKKRRRKTKK 122 EEEE+KKKK+ +K ++ Sbjct: 2283 EEEEKKKKKKEKKKEE 2298 Score = 76.6 bits (187), Expect = 4e-15 Identities = 44/118 (37%), Positives = 74/118 (62%), Gaps = 3/118 (2%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 ++++++++E E EE EE +EEEE E K+ EK +E EK+KKKK K+ E+ +EKEE + Sbjct: 2251 REEEEEREEEEVREEEEERKEEEEGEEKQVEKEEE---EKKKKKKEKKKEEVQEKEEVFE 2307 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRR 118 +++ +++ E +EEEEEE EEE E KK+K+ + +E+ + + R R Sbjct: 2308 EKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRRKSLRGRER 2365 Score = 76.3 bits (186), Expect = 6e-15 Identities = 35/114 (30%), Positives = 78/114 (68%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61 +K+K+ K ++ +E ++ +E + + + E ++ +K+++ +E+ +E+EEEE++ Sbjct: 2198 RKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEER 2257 Query: 62 RKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKK 115 + + ++++EE + EEE EE++ EKEEEEK++ ++ KKK++ + KEE E+K++ Sbjct: 2258 EEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEE 2311 Score = 75.1 bits (183), Expect = 1e-14 Identities = 42/114 (36%), Positives = 71/114 (62%), Gaps = 7/114 (6%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 +K+K+ K+ + E+ +E E E E+ + E EK++ E+ + +EEEE+ Sbjct: 2198 RKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEER 2257 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKK 114 + + R+ EEEER+EEEE EE++ E+EE+E +KKKKK ++KEE +EK++ Sbjct: 2258 EEEEVRE---EEEERKEEEEGEEKQVEKEEEE----KKKKKKEKKKEEVQEKEE 2304 Score = 58.5 bits (140), Expect = 1e-09 Identities = 39/141 (27%), Positives = 76/141 (53%), Gaps = 18/141 (12%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEK------RKEKRKEKEKKKKTKETEKRKE 54 K++K ++E++ + E ++E+EG +E+ ++ RK KE K+ K EK Sbjct: 2156 KEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSS 2215 Query: 55 KEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRK---KKKKRRRKEEE-- 109 + +E + + ++ + + E++E E+EEE +EE R + ++++ RKEEE Sbjct: 2216 QVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEG 2275 Query: 110 -------EEKKKKRRRKTKKK 123 EE++KK+++K KKK Sbjct: 2276 EEKQVEKEEEEKKKKKKEKKK 2296 Score = 53.5 bits (127), Expect = 4e-08 Identities = 37/138 (26%), Positives = 73/138 (52%), Gaps = 17/138 (12%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKE---------KEKKKKTKETEKR 52 K+++ K E E T E E + E EEKE + E+++ ++E + + +K + E+R Sbjct: 1534 KEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEER 1593 Query: 53 KEKEEEEKKRKRKRKKKKEEEE--------REEEEEEEEEEKEEEEKEEGRRRKKKKKRR 104 K +EEEK + +R+ +EE + +++ E + E + +KEE ++ +K + Sbjct: 1594 KLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQ 1653 Query: 105 RKEEEEEKKKKRRRKTKK 122 E+ +K+KK +K +K Sbjct: 1654 EAEKLAQKRKKLAKKWEK 1671 Score = 52.8 bits (125), Expect = 7e-08 Identities = 39/137 (28%), Positives = 72/137 (52%), Gaps = 19/137 (13%) Query: 6 KKKETEETEETEET-EEEEEKEGKRKEKR--KEKRKEKEKKKKTKETEKRKEKEEEEKKR 62 K KE + +E E T EEE +EG+ KE++ +E+R +E+ K + KR E++ + Sbjct: 1532 KSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQE 1591 Query: 63 KRKRKKKKEEEEREEEEEEEEEEK------------EEEEKEEGRRRKKK----KKRRRK 106 +RK +++E+ +EE + +EE K E + EG+ +K+ ++ + Sbjct: 1592 ERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKL 1651 Query: 107 EEEEEKKKKRRRKTKKK 123 +E EK ++R+K KK Sbjct: 1652 SQEAEKLAQKRKKLAKK 1668 Score = 52.0 bits (123), Expect = 1e-07 Identities = 36/121 (29%), Positives = 63/121 (52%), Gaps = 1/121 (0%) Query: 3 KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKR 62 +K K EE E+ EEE+ + K +E+ +++KK K +E ++ E K Sbjct: 1475 RKSWKAWKEEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKS- 1533 Query: 63 KRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKK 122 K ++ K +EE EEE E EEKE++ EE R +++ K R + + +K+R + ++ Sbjct: 1534 KEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEER 1593 Query: 123 K 123 K Sbjct: 1594 K 1594 Score = 51.2 bits (121), Expect = 2e-07 Identities = 41/158 (25%), Positives = 73/158 (46%), Gaps = 35/158 (22%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEK----------RKEKRKEKEKKKKTKETE 50 ++ K KE + +E+ E ++E+K +++ K ++EK E+E K K +E Sbjct: 2114 EQSKLDIKEWDFSEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSE 2173 Query: 51 KRKEKEEEE-----------KKRKRKRKKKK--------------EEEEREEEEEEEEEE 85 + EEE K+R RKRK+ K E E E EE E Sbjct: 2174 VILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESL 2233 Query: 86 KEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123 +E EK+E +++++R +EE EE++ + + +K+ Sbjct: 2234 LDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKE 2271 Score = 49.7 bits (117), Expect = 6e-07 Identities = 37/118 (31%), Positives = 64/118 (54%), Gaps = 13/118 (11%) Query: 8 KETEETEETEETE-EEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKR 66 +E E +E EE E + EE K +E +E+ K E+KKK E EE+ +R Sbjct: 1710 QEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAE---------EEEALAWQR 1760 Query: 67 KKKKEEEEREEEEEE---EEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTK 121 +K EEE + +EEE +E+EK + KE+ +++ R+R++ E+K K +++ + Sbjct: 1761 EKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRER 1818 Score = 46.2 bits (108), Expect = 6e-06 Identities = 45/137 (32%), Positives = 68/137 (49%), Gaps = 18/137 (13%) Query: 1 KKKKKKKKETEETEE--TEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKE-- 56 +K KK + E + ++ EE ++E + KE +E E+ + E KE+E Sbjct: 1677 EKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELN 1736 Query: 57 EEEKKRKRKRKKKKEEEE-----REEEEEEE-----EEEKEEEEKEEGRRRKKKKKRRRK 106 +EE K ++KK EEEE RE+ EEE EEE +EKE+ + K+K Sbjct: 1737 QEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEK----MP 1792 Query: 107 EEEEEKKKKRRRKTKKK 123 EEEE +KR + +KK Sbjct: 1793 EEEERLGRKREQLIEKK 1809 Score = 45.8 bits (107), Expect = 8e-06 Identities = 28/132 (21%), Positives = 73/132 (55%), Gaps = 10/132 (7%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKK-------KKTKETEKRKE 54 K++ +K+ +E E+ + E+ E + ++ K+ + E+ K+ K+KE + + E Sbjct: 1482 KEEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDE 1541 Query: 55 KE---EEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEE 111 +E EEE R+ + K+++ EE+ +EE + + ++ +++ +++R+ +EEE+ Sbjct: 1542 EEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEK 1601 Query: 112 KKKKRRRKTKKK 123 ++ R+ +++ Sbjct: 1602 LAQEERQLAQEE 1613 Score = 45.8 bits (107), Expect = 8e-06 Identities = 32/128 (25%), Positives = 72/128 (56%), Gaps = 6/128 (4%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 K K ++ K+ E + +++E++ K+ + +E +E E+K++ + TE+++ +EE K Sbjct: 1515 KLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQ-QVTEEQRHIQEEHK 1573 Query: 61 ----KRKRKR-KKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKK 115 RKR R +KK+ +EER+ +EEE+ +EE + + R+ + + +++ E + Sbjct: 1574 WARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQA 1633 Query: 116 RRRKTKKK 123 + +K+ Sbjct: 1634 EGKFAQKE 1641 Score = 45.8 bits (107), Expect = 8e-06 Identities = 41/148 (27%), Positives = 76/148 (51%), Gaps = 30/148 (20%) Query: 2 KKKKKKKETEETE-ETEET----EEEEEKEGKRKEKRKEKRKEKE------KKKKTKETE 50 ++K+ +E EE E + EE EE ++EGK E++K+ +E+E +K +ET+ Sbjct: 1710 QEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETK 1769 Query: 51 KRKEKE---EEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRR----------- 96 +E+E +E++K + ++K EEEER + E+ EK+ + ++ R Sbjct: 1770 LAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKN 1829 Query: 97 -----RKKKKKRRRKEEEEEKKKKRRRK 119 +KK + +K +EK+K +RK Sbjct: 1830 KMILYQKKNLAQEKKNLAQEKEKLAQRK 1857 Score = 44.7 bits (104), Expect = 2e-05 Identities = 28/106 (26%), Positives = 55/106 (51%) Query: 7 KKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKR 66 K+ E+++ +E + KR E K+++K K++K +R +EE+ + + Sbjct: 2107 KERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESK 2166 Query: 67 KKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEK 112 +K E ++EEE E+EE RR +K+K+ +R ++ +EK Sbjct: 2167 LARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEK 2212 Score = 43.5 bits (101), Expect = 4e-05 Identities = 38/133 (28%), Positives = 69/133 (51%), Gaps = 10/133 (7%) Query: 1 KKKKKKKKETEETE----ETEETEEEEEKEGKRKEKR-KEKRKEKEKKKKTKETEKRKEK 55 K ++KKK EE E + E+ EEE K + +E +EK K + K+K E E+R + Sbjct: 1741 KLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGR 1800 Query: 56 EEE---EKKRKRKRKKKKEEEEREEEEEEEE--EEKEEEEKEEGRRRKKKKKRRRKEEEE 110 + E EKK K +K+++ EE + + +K+ +E+ ++K+K +++E Sbjct: 1801 KREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENL 1860 Query: 111 EKKKKRRRKTKKK 123 K+R +KK+ Sbjct: 1861 LYNKERLTHSKKQ 1873 Score = 43.1 bits (100), Expect = 5e-05 Identities = 31/122 (25%), Positives = 63/122 (51%), Gaps = 8/122 (6%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKE------KRKEKEKKKKTKETEKRKE 54 +++K ++ET+ +E E +E+EK + KEK E +++E+ +KK K +KR+ Sbjct: 1759 QREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRER 1818 Query: 55 --KEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEK 112 EE + + +K+ +E++ +E+EK + KE K++ +K+ + K Sbjct: 1819 WINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVK 1878 Query: 113 KK 114 K Sbjct: 1879 NK 1880 Score = 42.7 bits (99), Expect = 7e-05 Identities = 32/100 (32%), Positives = 53/100 (53%), Gaps = 5/100 (5%) Query: 1 KKKKKKKKETEETEETEETEEEEEK----EGKRKEKRKEKRKEKEKKKKTKETEK-RKEK 55 ++ +KK ++ EET+ ++ +K E KE K++EKK K ++ RK Sbjct: 1348 EQAQKKARDMLGLEETQVILKKGKKVIFLEPGNVTMGKEISKKEEKKTFQKSPKQGRKAV 1407 Query: 56 EEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGR 95 ++E K K KR+ KEE + EE EE +E+ K+EG+ Sbjct: 1408 QKERKVGKIKREMTKEERDMSEEVEEMATLEEKVVKQEGK 1447 Score = 42.4 bits (98), Expect = 9e-05 Identities = 43/141 (30%), Positives = 68/141 (48%), Gaps = 22/141 (15%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKR--KEKRKEKEKKK-KTKE---TEKRKE 54 K K K + T + + +EE K K K KE+R E+ K KE +EKR E Sbjct: 2072 KLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSE 2131 Query: 55 KEEEEKKRKRKRKK---------KKEEEEREEEEEEEEEEKEE--EEKEEGRRRKKK--- 100 ++EKK RK++K KEE+ EEE + + E +++EEG +++ Sbjct: 2132 LTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIP 2191 Query: 101 --KKRRRKEEEEEKKKKRRRK 119 K+R RK +E ++ K + K Sbjct: 2192 FLKRRWRKRKEAKRGDKPKEK 2212 Score = 42.0 bits (97), Expect = 1e-04 Identities = 39/134 (29%), Positives = 68/134 (50%), Gaps = 17/134 (12%) Query: 4 KKKKKETEETEETEETEEEEEKEGKRKEKRKEK------RKEKEKKKKTKETEKRK---E 54 K +KE + E+ +E EK ++++K +K +EK KK K E + + Sbjct: 1636 KFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQ 1695 Query: 55 KEEEEKKRKR-----KRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEE 109 K EE +R++ +++ +E EE E + EE ++EE +EEG+ ++KKK EE Sbjct: 1696 KVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKL---AEE 1752 Query: 110 EEKKKKRRRKTKKK 123 EE +R K ++ Sbjct: 1753 EEALAWQREKLSEE 1766 Score = 42.0 bits (97), Expect = 1e-04 Identities = 34/130 (26%), Positives = 68/130 (52%), Gaps = 9/130 (6%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEK-RKEKRKEKEKKKKTKETEKRKEKEEEE 59 K++ ++ + ++E E+ ++ +K K+ EK +E+ K +K K E + ++ EE Sbjct: 1640 KEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEE 1699 Query: 60 KKRKRKRKKKKEEEEREEEEE-----EEEEEKEEEEKEEGRRRKKKKKRRRKEEEE---E 111 ++ + +E+E +E EE EE KEEE +E + ++KK+ +EEE + Sbjct: 1700 LPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQ 1759 Query: 112 KKKKRRRKTK 121 ++K +TK Sbjct: 1760 REKLSEEETK 1769 Score = 41.6 bits (96), Expect = 2e-04 Identities = 29/115 (25%), Positives = 61/115 (53%), Gaps = 16/115 (13%) Query: 4 KKKKKETEETEETEETEEEEEK---EGKRKEKRKEKRKEKE-------------KKKKTK 47 +K E E +E ++ + EE K E K KE++ + E ++K+ + Sbjct: 1501 EKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQ 1560 Query: 48 ETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKK 102 TE+++ +EE K + RK+ + E++R +EE + +E+E+ +EE + ++++K Sbjct: 1561 VTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERK 1615 Score = 40.8 bits (94), Expect = 3e-04 Identities = 25/125 (20%), Positives = 68/125 (54%), Gaps = 3/125 (2%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRK---EKRKEKEKKKKTKETEKRKEKEEE 58 ++++K + E EE +E+K+ K +E ++ K K+++ K+ E+ +EE Sbjct: 1491 QEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEV 1550 Query: 59 EKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRR 118 ++ + K ++ EE+ +EE + + + E +R ++++K ++EE+ +++++ Sbjct: 1551 SREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLA 1610 Query: 119 KTKKK 123 + ++K Sbjct: 1611 QEERK 1615 Score = 38.1 bits (87), Expect = 0.002 Identities = 29/118 (24%), Positives = 56/118 (47%), Gaps = 11/118 (9%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61 +K+ + ++ EE + +EEE+ + ++ +E+RK + K T+ +E + E K Sbjct: 1579 RKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQ--AYVKITQDDREMAQAEGK 1636 Query: 62 RKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRK 119 +K + + E+ +E E+ +K R+K KK + EEEK K+ K Sbjct: 1637 FAQKEETLAQRGEKLSQEAEKLAQK---------RKKLAKKWEKVAREEEKLAKKGGK 1685 Score = 38.1 bits (87), Expect = 0.002 Identities = 29/110 (26%), Positives = 54/110 (49%), Gaps = 9/110 (8%) Query: 23 EEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKR-----KRKKKKEEEEREE 77 +++E KE K + K +K T++ K ++E + K KR +R+ E+ + + Sbjct: 2061 KKRESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDI 2120 Query: 78 EEEEEEEEKEEEEKEEGR----RRKKKKKRRRKEEEEEKKKKRRRKTKKK 123 +E + E++ E K+E + +RK K RR +EEK + K +K Sbjct: 2121 KEWDFSEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARK 2170 Score = 37.7 bits (86), Expect = 0.002 Identities = 35/115 (30%), Positives = 61/115 (53%), Gaps = 14/115 (12%) Query: 8 KETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRK 67 KE + EE ++T ++ K+G RK +KE++ K K++ TKE +R EE E+ + K Sbjct: 1385 KEISKKEE-KKTFQKSPKQG-RKAVQKERKVGKIKREMTKE--ERDMSEEVEEMATLEEK 1440 Query: 68 KKKEEE-----EREEEEEEEEEEKEEEEKEEGRRRK-----KKKKRRRKEEEEEK 112 K+E ER ++ ++ +E ++ G RK K++ +R +EEEK Sbjct: 1441 VVKQEGKLVMIERTPSWQDWKKAWDEWKQVHGETRKSWKAWKEEWEKRLLQEEEK 1495 Score = 36.6 bits (83), Expect = 0.005 Identities = 29/127 (22%), Positives = 65/127 (51%), Gaps = 6/127 (4%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGK-RKEKRKEKRKEKEKKKKTKETEKRKEKEEE-- 58 KK++KK + ++ + ++E K GK ++E KE+R E+ ++ E++ K+E Sbjct: 1389 KKEEKKTFQKSPKQGRKAVQKERKVGKIKREMTKEERDMSEEVEEMATLEEKVVKQEGKL 1448 Query: 59 ---EKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKK 115 E+ + KK +E ++ E + K +E+ E R ++++K + E+ +++ Sbjct: 1449 VMIERTPSWQDWKKAWDEWKQVHGETRKSWKAWKEEWEKRLLQEEEKLHQAGEKLSPEEE 1508 Query: 116 RRRKTKK 122 ++ KK Sbjct: 1509 MLQEDKK 1515 Score = 35.8 bits (81), Expect = 0.008 Identities = 26/106 (24%), Positives = 51/106 (48%) Query: 18 ETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREE 77 + EE+ +E + K+KEK E EKK E K++E+ +++ + +K + ++ Sbjct: 1890 QVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKR 1949 Query: 78 EEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123 E + KEE+ +R ++K R E +E K +T ++ Sbjct: 1950 LRGELDIAKEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQ 1995 Score = 34.7 bits (78), Expect = 0.019 Identities = 33/124 (26%), Positives = 62/124 (50%), Gaps = 12/124 (9%) Query: 1 KKKKKKKKET--EETEETEETEEE----EEKEGKRKEKRKEKRKEKEKKKKTKETEKRKE 54 ++K ++KET ++ E+ ETE++ E+ K++EK +++ + +K + +KR Sbjct: 1892 EEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLR 1951 Query: 55 KE----EEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKR--RRKEE 108 E +EEK + K+ EE+ R E +E + E E R+ + ++ RK Sbjct: 1952 GELDIAKEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLS 2011 Query: 109 EEEK 112 EEK Sbjct: 2012 LEEK 2015 Score = 34.3 bits (77), Expect = 0.024 Identities = 28/128 (21%), Positives = 65/128 (50%), Gaps = 14/128 (10%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRK---------EKRKEKRKEKEKKKKTKET-- 49 KK+ +++++ + EE EE + + +RK + +E + + K + +ET Sbjct: 1586 KKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLA 1645 Query: 50 ---EKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRK 106 EK ++ E+ ++++K KK E+ REEE+ ++ K E K ++ ++ +R + Sbjct: 1646 QRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQ 1705 Query: 107 EEEEEKKK 114 + ++K+ Sbjct: 1706 NLDWQEKE 1713 Score = 34.3 bits (77), Expect = 0.024 Identities = 29/111 (26%), Positives = 53/111 (47%), Gaps = 8/111 (7%) Query: 14 EETEETEEEEEKEGKRKEK---RKEKRKEKEK-----KKKTKETEKRKEKEEEEKKRKRK 65 +E + +E+EK +RKE KE+ +K K K K + EE+ ++++ Sbjct: 1841 QEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKE 1900 Query: 66 RKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKR 116 KK+E+ E E++ + E +K+E ++K K K + KK+ R Sbjct: 1901 TVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLR 1951 Score = 33.9 bits (76), Expect = 0.032 Identities = 30/126 (23%), Positives = 59/126 (46%), Gaps = 3/126 (2%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 K++K K + E T+E + EE E+ +EK ++ + ++T + K+ +E K Sbjct: 1409 KERKVGKIKREMTKEERDMSEEVEEMATLEEKVVKQEGKLVMIERTPSWQDWKKAWDEWK 1468 Query: 61 K---RKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRR 117 + RK K +EE + +EEE+ + EK ++ ++ K EE ++ + Sbjct: 1469 QVHGETRKSWKAWKEEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENM 1528 Query: 118 RKTKKK 123 +K K Sbjct: 1529 LSSKSK 1534 Score = 33.9 bits (76), Expect = 0.032 Identities = 34/129 (26%), Positives = 61/129 (47%), Gaps = 6/129 (4%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKR---KEKEKKKKTKET-EKRKEKE 56 KK K +K EE + + ++K +EK+ +EKEK + KE KE+ Sbjct: 1808 KKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERL 1867 Query: 57 EEEKKR--KRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKK 114 KK+ + K K + + EE+ +EKE K++ + + +KK + E+ KK+ Sbjct: 1868 THSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQ 1927 Query: 115 KRRRKTKKK 123 ++ + K K Sbjct: 1928 EKLAQEKMK 1936 Score = 33.1 bits (74), Expect = 0.054 Identities = 27/109 (24%), Positives = 53/109 (48%), Gaps = 3/109 (2%) Query: 9 ETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKK 68 E + T+E E +++EK + ++K + KK++ EK K E+ + +KR + Sbjct: 1892 EEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLR 1951 Query: 69 KKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRR 117 + + +EE+ E ++ EEK R + K+ K E E ++R+ Sbjct: 1952 GELDIAKEEKALNLEMKRLAEEK---MRLVEGKETLSKGETPETSRQRK 1997 Score = 32.7 bits (73), Expect = 0.071 Identities = 24/101 (23%), Positives = 51/101 (50%), Gaps = 1/101 (0%) Query: 23 EEKEGKRKEKRK-EKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEE 81 +EK+ +EK K +RKE K + T +K+ + + K K + EE+ +E+E Sbjct: 1841 QEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKE 1900 Query: 82 EEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKK 122 +K+E+ E ++ + + K++E+ ++K + +K Sbjct: 1901 TVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEK 1941 Score = 32.3 bits (72), Expect = 0.093 Identities = 30/124 (24%), Positives = 60/124 (48%), Gaps = 5/124 (4%) Query: 3 KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKR 62 KK+ + E + +E E+ E K ++ R + KE K +T ET ++++ + E++ Sbjct: 1947 KKRLRGELDIAKE-EKALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQEL 2005 Query: 63 KRKRKKKKEE----EEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRR 118 ++ +E+ E+R EE E K + E G+R + +R+ + + KKR Sbjct: 2006 FERKLSLEEKILLHEDRILAMEESEIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRES 2065 Query: 119 KTKK 122 +K+ Sbjct: 2066 LSKE 2069 Score = 31.6 bits (70), Expect = 0.16 Identities = 23/117 (19%), Positives = 55/117 (47%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 +KK +++ +E E+ + +E KE+ +K+ + K + + EEK Sbjct: 1835 QKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEK 1894 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRR 117 + K K++E+ E E++ + ++ K++ + ++K K ++ + KK+ R Sbjct: 1895 LTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLR 1951 Score = 31.2 bits (69), Expect = 0.21 Identities = 27/112 (24%), Positives = 55/112 (49%), Gaps = 8/112 (7%) Query: 20 EEEEEKEGKRKEKRKEK---RKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEERE 76 EE E +GK + R ++ + +++ K +++ K++E +E + K K ++ R+ Sbjct: 2027 EESEIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLNKILKALQKLTRD 2086 Query: 77 EEEEEEEEEKEEEEK-----EEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123 E + +EE K + K +E R ++ K KE + +K+ K +KK Sbjct: 2087 ERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKK 2138 Score = 29.3 bits (64), Expect = 0.79 Identities = 20/88 (22%), Positives = 47/88 (53%), Gaps = 1/88 (1%) Query: 30 KEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKE-E 88 + K R+E++ +KK ++ +E + KK K+ + +E ++EE+K + Sbjct: 1338 RHKEVMPREEEQAQKKARDMLGLEETQVILKKGKKVIFLEPGNVTMGKEISKKEEKKTFQ 1397 Query: 89 EEKEEGRRRKKKKKRRRKEEEEEKKKKR 116 + ++GR+ +K+++ K + E K++R Sbjct: 1398 KSPKQGRKAVQKERKVGKIKREMTKEER 1425 Score = 28.1 bits (61), Expect = 1.8 Identities = 27/92 (29%), Positives = 44/92 (47%), Gaps = 14/92 (15%) Query: 46 TKETEKRKE--KEEEEKKRKRKRKK----------KKEEEEREEEEEEEEEEKEEEEKEE 93 T+E + KE EEE+ +K+ R KK ++ E KE +KEE Sbjct: 1333 TQEVIRHKEVMPREEEQAQKKARDMLGLEETQVILKKGKKVIFLEPGNVTMGKEISKKEE 1392 Query: 94 GRRRKKKKKRRRKEEEEEKK--KKRRRKTKKK 123 + +K K+ RK ++E+K K +R TK++ Sbjct: 1393 KKTFQKSPKQGRKAVQKERKVGKIKREMTKEE 1424 Score = 28.1 bits (61), Expect = 1.8 Identities = 33/137 (24%), Positives = 56/137 (40%), Gaps = 17/137 (12%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRK---EKRKEKEKKKKTKETEKRKEKEEE 58 KKK+K ETE+ E +++E +EK K EK + KK+ E + KE++ Sbjct: 1904 KKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKAL 1963 Query: 59 EKKRKRKRKKKKE--------------EEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRR 104 + KR ++K E R+ + + E+E E + + + R Sbjct: 1964 NLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKILLHEDRI 2023 Query: 105 RKEEEEEKKKKRRRKTK 121 EE E K + T+ Sbjct: 2024 LAMEESEIAKGKLEFTR 2040 Score = 27.7 bits (60), Expect = 2.3 Identities = 14/51 (27%), Positives = 29/51 (56%) Query: 6 KKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKE 56 K + +++E + +++ KR +K ++KR +K +K K+ K+K KE Sbjct: 1148 KLSKDVDSQEKDISKDHIALTLKRLQKIRDKRDKKATAQKLKKKHKKKGKE 1198 Score = 26.9 bits (58), Expect = 3.9 Identities = 17/55 (30%), Positives = 29/55 (52%), Gaps = 2/55 (3%) Query: 43 KKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEE--EEEKEEEEKEEGR 95 K+ K +KR +K +K +K+ +KK KE + EE E+ ++ K +GR Sbjct: 1170 KRLQKIRDKRDKKATAQKLKKKHKKKGKEAKVINEETTPPVMEQPVTKKVKIQGR 1224 Score = 26.2 bits (56), Expect = 6.7 Identities = 25/127 (19%), Positives = 56/127 (44%), Gaps = 19/127 (14%) Query: 16 TEETEEE-EEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEE 74 +EE+E + +G+R+ + K+ ++ + K+T++R K+ + + + E Sbjct: 1069 SEESEVAIKPSKGQRRGQAGVKKHSQKWLRGLKKTKERDSKQMSTEPGLLEDESGTEAAP 1128 Query: 75 REEEE------------------EEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKR 116 E EE + + +EK+ + K+ +K R K +++ +K Sbjct: 1129 IEMEEASVYSQWSSSTSVIKLSKDVDSQEKDISKDHIALTLKRLQKIRDKRDKKATAQKL 1188 Query: 117 RRKTKKK 123 ++K KKK Sbjct: 1189 KKKHKKK 1195 Score = 26.2 bits (56), Expect = 6.7 Identities = 23/92 (25%), Positives = 44/92 (47%), Gaps = 3/92 (3%) Query: 34 KEKRKEKEKKKKTKETEKRKEKEE---EEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEE 90 +E + KE + +E ++K ++ EE + K+ KK E +E K+EE+ Sbjct: 1334 QEVIRHKEVMPREEEQAQKKARDMLGLEETQVILKKGKKVIFLEPGNVTMGKEISKKEEK 1393 Query: 91 KEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKK 122 K + K+ +K +KE + K K+ K ++ Sbjct: 1394 KTFQKSPKQGRKAVQKERKVGKIKREMTKEER 1425 Score = 25.8 bits (55), Expect = 8.7 Identities = 14/44 (31%), Positives = 24/44 (54%) Query: 20 EEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRK 63 ++ ++K +K K+K K+K KE K +ET ++ KK K Sbjct: 1177 DKRDKKATAQKLKKKHKKKGKEAKVINEETTPPVMEQPVTKKVK 1220 >gi|55741709 RNA binding motif protein 25 [Homo sapiens] Length = 843 Score = 89.0 bits (219), Expect = 8e-19 Identities = 51/157 (32%), Positives = 88/157 (56%), Gaps = 35/157 (22%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKK-------------KTKE 48 KK+K+++E E+ E E E E+E + +E+ +E+ +E+EK+K +TKE Sbjct: 297 KKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRDRDRTKE 356 Query: 49 TEKRKEKEEE-------------------EKKRKRKRKKKKE-EEEREEEEEEEEEEKEE 88 ++ +++E + EK R R+R++++E E ERE E E E E + E Sbjct: 357 RDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERE 416 Query: 89 EEKEEGRRRKKKKKRRRKEEEEE--KKKKRRRKTKKK 123 E+E R R+K KKR R+E+EE+ +++K RK ++K Sbjct: 417 REREREREREKDKKRDREEDEEDAYERRKLERKLREK 453 Score = 83.6 bits (205), Expect = 4e-17 Identities = 33/123 (26%), Positives = 78/123 (63%), Gaps = 1/123 (0%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 K +++K K+ +E +E E+ E E+E +R+ +R+E+ +E+E++++ +E EK +E+E E Sbjct: 290 KLEEEKGKKEKERQEIEKERRERERERERERERRERERERERERE-REKEKERERERERD 348 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120 + + + K++ + +RE + + + E + K+ R R+K + R R+ E E ++++ R + Sbjct: 349 RDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERE 408 Query: 121 KKK 123 +++ Sbjct: 409 RER 411 Score = 76.6 bits (187), Expect = 4e-15 Identities = 47/144 (32%), Positives = 78/144 (54%), Gaps = 21/144 (14%) Query: 1 KKKKKKKKE-----------------TEETEETEETEEEEEKEGKR---KEKRKEKRKEK 40 +KKKK+KKE T+E E EE++ R K + K+ E+ Sbjct: 234 RKKKKEKKEDIFRRFPVAPLIPYPLITKEDINAIEMEEDKRDLISREISKFRDTHKKLEE 293 Query: 41 EKKKKTKETEK-RKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKK 99 EK KK KE ++ KE+ E E++R+R+R++++ E ERE E E E+E++ E E+E R R + Sbjct: 294 EKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRDRDR 353 Query: 100 KKKRRRKEEEEEKKKKRRRKTKKK 123 K+R R + E + + R ++ + Sbjct: 354 TKERDRDRDRERDRDRDRERSSDR 377 Score = 76.6 bits (187), Expect = 4e-15 Identities = 34/130 (26%), Positives = 79/130 (60%), Gaps = 8/130 (6%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEE-- 58 +++ + + T+E + + E + +++ +R R + R +K + +E E+ +E+E E Sbjct: 345 RERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERE 404 Query: 59 -EKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKK-- 115 E++R+R+R++++E E E E++++ ++EE+E++ RRK ++K R KE +++ K Sbjct: 405 REREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNW 464 Query: 116 ---RRRKTKK 122 R+KT++ Sbjct: 465 EIRERKKTRE 474 Score = 75.1 bits (183), Expect = 1e-14 Identities = 33/123 (26%), Positives = 78/123 (63%), Gaps = 2/123 (1%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61 ++ K+ + E + +T ++ E+E +KEK +++ EKE++++ +E E+ +E+ E E++ Sbjct: 270 EEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEI-EKERRERERERERERERRERERE 328 Query: 62 RKRKRKKKKEEE-EREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120 R+R+R+++KE+E ERE E + + + +E +++ R R + + R R + + + + R K+ Sbjct: 329 REREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKS 388 Query: 121 KKK 123 + + Sbjct: 389 RDR 391 Score = 73.9 bits (180), Expect = 3e-14 Identities = 31/137 (22%), Positives = 81/137 (59%), Gaps = 14/137 (10%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 ++ + + +E + + E + + + + +EK +++ +E+E++++ + +R+ + E E+ Sbjct: 356 ERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERER 415 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRK--------------KKKKRRRK 106 +R+R+R++++E++++ + EE+EE+ E + E R K ++KK R Sbjct: 416 EREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREY 475 Query: 107 EEEEEKKKKRRRKTKKK 123 E+E E++++RRR+ K+ Sbjct: 476 EKEAEREEERRREMAKE 492 Score = 69.7 bits (169), Expect = 5e-13 Identities = 34/124 (27%), Positives = 72/124 (58%), Gaps = 13/124 (10%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 K + + ++++ + E E E E E+E +R+ +R+ +R+ + ++++ +E +K++++EE+E+ Sbjct: 379 KDRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEE 438 Query: 61 KRKRKRKKKKEEEERE-------------EEEEEEEEEKEEEEKEEGRRRKKKKKRRRKE 107 +RK +++ E+E E ++ E EKE E +EE RR K+ +R KE Sbjct: 439 DAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKE 498 Query: 108 EEEE 111 E+ Sbjct: 499 FLED 502 Score = 68.2 bits (165), Expect = 2e-12 Identities = 33/122 (27%), Positives = 71/122 (58%), Gaps = 1/122 (0%) Query: 2 KKKKKKKETEETEETE-ETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 + K + + E++ + E E E E E+E +R+ +R+ +R+ + ++++ +E EK K+++ EE Sbjct: 377 RNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRDREED 436 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120 + ++K E + RE+E +E K E +E + R+ +K+ R+EE + K ++ Sbjct: 437 EEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRL 496 Query: 121 KK 122 K+ Sbjct: 497 KE 498 Score = 64.7 bits (156), Expect = 2e-11 Identities = 35/130 (26%), Positives = 76/130 (58%), Gaps = 16/130 (12%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEK-----------EKKKKTKET 49 ++++++++E E+ ++ + E+EE+ +RK +RK + KE ++KKT+E Sbjct: 416 EREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREY 475 Query: 50 EKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEE 109 EK E+EEE R+R+ KE + +E E+ ++++++ + G +K+ + R KE E Sbjct: 476 EKEAEREEE-----RRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEME 530 Query: 110 EEKKKKRRRK 119 +++ ++R K Sbjct: 531 ADERDRKREK 540 Score = 62.0 bits (149), Expect = 1e-10 Identities = 37/144 (25%), Positives = 76/144 (52%), Gaps = 35/144 (24%) Query: 5 KKKKETEETEETEETEEEEEKEGKRKEKR-----------------------KEKRKEKE 41 +++K+T E E+ E EEE +E ++ KR +++ +++E Sbjct: 467 RERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDRE 526 Query: 42 KKKKTKETEKRKEKEEEEKKRKRK------------RKKKKEEEEREEEEEEEEEEKEEE 89 K+ + E ++++EKEE E+ R+R ++ ++E E R + + ++E E EEE Sbjct: 527 KEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEE 586 Query: 90 EKEEGRRRKKKKKRRRKEEEEEKK 113 E+E+ + +K+++ +EEE E+K Sbjct: 587 EEEKQEKEEKREEPMEEEEEPEQK 610 Score = 60.5 bits (145), Expect = 3e-10 Identities = 43/142 (30%), Positives = 78/142 (54%), Gaps = 20/142 (14%) Query: 2 KKKKKKKETEETEETEETEEE-EEKEGKRKEKRKEKRKEKE------------KKKKTKE 48 +++ K E E ++T E E+E E +E +R+E KE ++ KE K + Sbjct: 458 QERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSA 517 Query: 49 TEKR---KEKEEEEKKRKRKRKKKKEEEERE----EEEEEEEEEKEEEEKEEGRRRKKKK 101 +KR +EKE E +R RKR+K++ EE R+ E + + E + E+E RRR+ + Sbjct: 518 LQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQI 577 Query: 102 KRRRKEEEEEKKKKRRRKTKKK 123 K+ + EEEE++K+ + + +++ Sbjct: 578 KQEPESEEEEEEKQEKEEKREE 599 Score = 50.1 bits (118), Expect = 4e-07 Identities = 23/92 (25%), Positives = 53/92 (57%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 +K+ + +++ E +E + E+EE E R+ E + + + + E E + ++ + K Sbjct: 519 QKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIK 578 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKE 92 + ++++E++E+EE+ EE EE+EE E++ Sbjct: 579 QEPESEEEEEEKQEKEEKREEPMEEEEEPEQK 610 Score = 48.1 bits (113), Expect = 2e-06 Identities = 38/168 (22%), Positives = 74/168 (44%), Gaps = 46/168 (27%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61 K KKK ET ++EE + + K + + + E + +E +E + Sbjct: 173 KAKKKASNGNARPETVTNDDEEALDEETKRRDQMIKGAIEVLIREYSSELNAPSQESDSH 232 Query: 62 RKRKRKKKKE---------------------------EEER------------------E 76 ++K+K+KKE EE++ E Sbjct: 233 PRKKKKEKKEDIFRRFPVAPLIPYPLITKEDINAIEMEEDKRDLISREISKFRDTHKKLE 292 Query: 77 EEEEEEEEEKEEEEKE-EGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123 EE+ ++E+E++E EKE R R+++++R R+E E E++++R R+ +K+ Sbjct: 293 EEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKE 340 Score = 33.9 bits (76), Expect = 0.032 Identities = 13/47 (27%), Positives = 33/47 (70%) Query: 3 KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKET 49 +++++ + ++ E+EE EEE++++ +++E+ E+ +E E+K K T Sbjct: 570 ERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKPCLKPT 616 Score = 30.0 bits (66), Expect = 0.46 Identities = 21/89 (23%), Positives = 41/89 (46%), Gaps = 6/89 (6%) Query: 41 EKKKKTKETEKRKEKEEEEKKRKRKRK--KKKEEEEREEEEEEEEEEKEEEEKEEGR--- 95 EKK K K K + +E K +K+ + E ++EE +EE K ++ +G Sbjct: 154 EKKLLVKVDAKTKAQLDEWKAKKKASNGNARPETVTNDDEEALDEETKRRDQMIKGAIEV 213 Query: 96 -RRKKKKKRRRKEEEEEKKKKRRRKTKKK 123 R+ + +E + ++++K KK+ Sbjct: 214 LIREYSSELNAPSQESDSHPRKKKKEKKE 242 >gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] Length = 1564 Score = 87.8 bits (216), Expect = 2e-18 Identities = 38/124 (30%), Positives = 80/124 (64%), Gaps = 1/124 (0%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKR-KEKRKEKRKEKEKKKKTKETEKRKEKEEEE 59 +++ ++++ E E E E+E E E +R +E+ +E+ KE+++++ R+ + E E Sbjct: 683 RERDRERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERE 742 Query: 60 KKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRK 119 + R+++R++++EE ERE E E E E + E E+E R R K+++R+R E+++K + RR+ Sbjct: 743 RDREKEREREREERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRRE 802 Query: 120 TKKK 123 +++ Sbjct: 803 KREE 806 Score = 84.7 bits (208), Expect = 2e-17 Identities = 40/124 (32%), Positives = 74/124 (59%), Gaps = 2/124 (1%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61 +++++ +E E E E E E++ +E+ +E+ +E+EK++ + R E E++ Sbjct: 681 RERERDRERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERE 740 Query: 62 RKRKRKKKKEEE--EREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRK 119 R+R R+K++E E ERE E E E E + E E+E R R++ K+R R+ + E+K K R + Sbjct: 741 RERDREKEREREREERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDR 800 Query: 120 TKKK 123 +K+ Sbjct: 801 REKR 804 Score = 81.3 bits (199), Expect = 2e-16 Identities = 34/124 (27%), Positives = 76/124 (61%), Gaps = 1/124 (0%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKE-EEE 59 ++++ + + E E + E E++ +R+ +R+ +R + +K++ E E+ +E+E E E Sbjct: 661 EERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERARERERERE 720 Query: 60 KKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRK 119 K+R R+R + ++ + E E E + EKE E + E R R+++++R R+ E E ++++ R + Sbjct: 721 KERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERERERERARER 780 Query: 120 TKKK 123 K++ Sbjct: 781 DKER 784 Score = 80.9 bits (198), Expect = 2e-16 Identities = 32/123 (26%), Positives = 76/123 (61%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 K+++ +++ E E E E + E++ R R+ +R+ + ++K +E E+ + + E E+ Sbjct: 703 KERELERERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERER 762 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120 +R+R+R++++E E E ++E E +++ E+K++GR +++K+ +E+ + RK+ Sbjct: 763 ERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKS 822 Query: 121 KKK 123 KK+ Sbjct: 823 KKR 825 Score = 79.3 bits (194), Expect = 7e-16 Identities = 35/124 (28%), Positives = 76/124 (61%), Gaps = 2/124 (1%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEK-KKKTKETEKRKEKEEEE 59 ++ ++ ++ E E E E E E+E R E+ KE+ E+E+ +++ +E EK +++E + Sbjct: 671 RRDERARERDRERERDRERERERERERDR-EREKERELERERAREREREREKERDRERDR 729 Query: 60 KKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRK 119 + + ++++ E +RE+E E E EE+E E + E R +++++ R + E +K+++R+R Sbjct: 730 DRDHDRERERERERDREKEREREREERERERERERERERERERERERARERDKERERQRD 789 Query: 120 TKKK 123 + K Sbjct: 790 WEDK 793 Score = 77.8 bits (190), Expect = 2e-15 Identities = 32/125 (25%), Positives = 79/125 (63%), Gaps = 4/125 (3%) Query: 3 KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEE-KK 61 ++ +++E + ++ +E +E R+ +R +R+ + ++++ +E EK +E E E ++ Sbjct: 655 ERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERARE 714 Query: 62 RKRKRKKKKEEE---EREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRR 118 R+R+R+K+++ E +R+ + E E E + + EKE R R+++++ R +E E E++++R R Sbjct: 715 REREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERERER 774 Query: 119 KTKKK 123 + ++ Sbjct: 775 ERARE 779 Score = 77.0 bits (188), Expect = 3e-15 Identities = 29/120 (24%), Positives = 74/120 (61%), Gaps = 1/120 (0%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61 +++ +++E + E E E + + K +E +E+ +E+E++++ KE ++ ++++ + + Sbjct: 677 RERDRERERDRERERERERERDREREKERELERERARERERERE-KERDRERDRDRDHDR 735 Query: 62 RKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTK 121 + + +++ E+ERE E EE E E+E E + E R +++++ R +++E E+++ K K Sbjct: 736 ERERERERDREKEREREREERERERERERERERERERERERARERDKERERQRDWEDKDK 795 Score = 76.3 bits (186), Expect = 6e-15 Identities = 28/122 (22%), Positives = 76/122 (62%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61 ++ +++ E + E E E E++ +R+++R+ +R+ ++++ +E E+ +E++ + Sbjct: 674 ERARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRERDRDRDH 733 Query: 62 RKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTK 121 + + ++++ + E+E E E EE E+E E + E R +++++ R +E ++E++++R + K Sbjct: 734 DRERERERERDREKEREREREERERERERERERERERERERERARERDKERERQRDWEDK 793 Query: 122 KK 123 K Sbjct: 794 DK 795 Score = 75.5 bits (184), Expect = 1e-14 Identities = 32/120 (26%), Positives = 78/120 (65%), Gaps = 2/120 (1%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEE-E 59 ++++ +++E E +E + + + + +E+ +E+ +EKE++++ +E E+ +E+E E E Sbjct: 708 ERERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERE 767 Query: 60 KKRKRKRKKKKE-EEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRR 118 ++R+R+R++ +E ++ERE + + E+++K +++ E R ++ + R +E K KKR R Sbjct: 768 RERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYR 827 Score = 72.8 bits (177), Expect = 6e-14 Identities = 32/121 (26%), Positives = 71/121 (58%), Gaps = 2/121 (1%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 + +++ + + E E E + EKE +R+ + +E+ +E+E++++ + +R+ E +K Sbjct: 723 RDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERERERERARERDK 782 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKK--KRRR 118 +R+R+R + +++ R++ E+ EE +E+ +G +K KKR R E ++ KRRR Sbjct: 783 ERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRR 842 Query: 119 K 119 + Sbjct: 843 E 843 Score = 63.2 bits (152), Expect = 5e-11 Identities = 30/112 (26%), Positives = 70/112 (62%), Gaps = 3/112 (2%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 ++++++ +E E E EE E E E+E +R E+ +E+ +E+ +++ KE E++++ E+++K Sbjct: 738 ERERERDREKEREREREERERERERERER-ERERERERER-ARERDKERERQRDWEDKDK 795 Query: 61 KRKRKRKKKKE-EEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEE 111 R +R+K++E E+R + +E + ++ + EG ++ +RR+E + Sbjct: 796 GRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPD 847 Score = 60.1 bits (144), Expect = 4e-10 Identities = 27/125 (21%), Positives = 70/125 (56%), Gaps = 3/125 (2%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 +++++++++ E+ E E E E E+E +R+ +R+ +R+ + +++ KE E++++ E+++K Sbjct: 736 ERERERERDREKEREREREERERERERERERERERERERERARERDKERERQRDWEDKDK 795 Query: 61 ---KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRR 117 R+ KR++ +E+ + +E + +K + R+ K+RR + + Sbjct: 796 GRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGD 855 Query: 118 RKTKK 122 K +K Sbjct: 856 DKNEK 860 Score = 59.7 bits (143), Expect = 5e-10 Identities = 24/123 (19%), Positives = 66/123 (53%), Gaps = 3/123 (2%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 +++ ++ + E + +G+ E +++R+E+ ++ + R+++ E+ Sbjct: 623 ERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREE---RRVDRVDDRRDERARER 679 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120 R+R+R +++E E E + E E+E+E E + R ++++K R +E + ++ R R+ Sbjct: 680 DRERERDRERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERER 739 Query: 121 KKK 123 +++ Sbjct: 740 ERE 742 Score = 55.1 bits (131), Expect = 1e-08 Identities = 22/122 (18%), Positives = 62/122 (50%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61 ++ + + + + E E + +R ++ + + + + + E+R+E+ + Sbjct: 610 ERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVD 669 Query: 62 RKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTK 121 +R + ++ + ERE + E E E + E ++E + R+ +++R R+ E E +K++ R + + Sbjct: 670 DRRDERARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRERDR 729 Query: 122 KK 123 + Sbjct: 730 DR 731 Score = 51.2 bits (121), Expect = 2e-07 Identities = 25/123 (20%), Positives = 61/123 (49%), Gaps = 4/123 (3%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 ++ + +++ + E + +R + +++R + + + E +++ EE+ Sbjct: 604 ERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREER 663 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKE-EEEKEEGRRRKKKK---KRRRKEEEEEKKKKR 116 + R ++ E + E E + E+E E E+E R R+K++ + R +E E E++K+R Sbjct: 664 RVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERAREREREREKER 723 Query: 117 RRK 119 R+ Sbjct: 724 DRE 726 Score = 48.9 bits (115), Expect = 1e-06 Identities = 31/133 (23%), Positives = 62/133 (46%), Gaps = 16/133 (12%) Query: 5 KKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEK--------- 55 K K + E+ EE E+ E++ +KR E +++ KR+ + Sbjct: 793 KDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYN 852 Query: 56 --EEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKK 113 +++ +K + + + +E R E+++ KEE R+ ++K+ RR EE+E K+ Sbjct: 853 SGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKE 912 Query: 114 K-----KRRRKTK 121 K K+R +T+ Sbjct: 913 KVSSVDKQREQTE 925 Score = 47.4 bits (111), Expect = 3e-06 Identities = 20/95 (21%), Positives = 49/95 (51%), Gaps = 1/95 (1%) Query: 23 EEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKK-KKEEEEREEEEEE 81 + K+ + + + K + ++T ++ R+ + E+ + KR R+K +EE E E+++ Sbjct: 383 QRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSS 442 Query: 82 EEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKR 116 + +++ E +GR R+ + R + E + + R Sbjct: 443 SRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMR 477 Score = 47.4 bits (111), Expect = 3e-06 Identities = 19/115 (16%), Positives = 56/115 (48%) Query: 9 ETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKK 68 ET + + E + + ++ E+R + ++ +E ++R + R + ++ Sbjct: 597 ETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELER 656 Query: 69 KKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123 + EER + ++ ++ E++ R R ++++R R+ E + +++K R +++ Sbjct: 657 DERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERER 711 Score = 44.7 bits (104), Expect = 2e-05 Identities = 36/144 (25%), Positives = 68/144 (47%), Gaps = 30/144 (20%) Query: 7 KKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEK----------------KKKTKETE 50 K+E + E E + EE+E K K +K++E+ + + + +ET Sbjct: 890 KEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETS 949 Query: 51 KRKEKEEEEKKRKRKR--KKKKEEEEREEEE--EEEEEEKEEEEKEEGRRRKKKKKRRRK 106 R E ++K + +K+ KKKKE++ E E E+ + ++G+++K +K+R+K Sbjct: 950 DRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIEKKRKK 1009 Query: 107 ----------EEEEEKKKKRRRKT 120 E ++ KKKR +T Sbjct: 1010 SKGDSDISDEEAAQQSKKKRGPRT 1033 Score = 43.9 bits (102), Expect = 3e-05 Identities = 36/152 (23%), Positives = 59/152 (38%), Gaps = 33/152 (21%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEE-- 59 +++ K K + E ++ EE RKE + + +EKE K TKE E+E E Sbjct: 86 RERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGRHREKEDIKITKERTPESEEENVEWE 145 Query: 60 -----------------------KKRKRKRKKKKEEEEREEEEEEEEEEKEEEEK----- 91 K++K +R+ K E+E E+ EE +KE + Sbjct: 146 TNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQENMEKREEIIIKKEVSPEVVRSK 205 Query: 92 ---EEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120 R+ K +R+ + K+ RKT Sbjct: 206 LSPSPSLRKSSKSPKRKSSPKSSSASKKDRKT 237 Score = 42.4 bits (98), Expect = 9e-05 Identities = 29/118 (24%), Positives = 53/118 (44%), Gaps = 17/118 (14%) Query: 23 EEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKK----KEEEEREEE 78 E G +E+ K KR++ + + + + TE+ +E R R R+K+ +E E E Sbjct: 79 ERPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGRHREKEDIKITKERTPESE 138 Query: 79 EEEEEEEKEEEEKEEG-------------RRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123 EE E E ++ + G +R+K ++ K E+E +K+ KK+ Sbjct: 139 EENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQENMEKREEIIIKKE 196 Score = 42.4 bits (98), Expect = 9e-05 Identities = 24/141 (17%), Positives = 67/141 (47%), Gaps = 20/141 (14%) Query: 3 KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKR 62 + ++ + + TE+ + ++E ++ E+++ R+ +E++ K K + K++E+ E Sbjct: 869 RPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILE 928 Query: 63 KRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEE-------------- 108 + + + + E+ E + +E K++ + +KK K++++++ Sbjct: 929 SSRMRAQDIIGHHQSEDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSED 988 Query: 109 ------EEEKKKKRRRKTKKK 123 ++ +KKK K +KK Sbjct: 989 GQVFSPKKGQKKKSIEKKRKK 1009 Score = 41.2 bits (95), Expect = 2e-04 Identities = 22/121 (18%), Positives = 57/121 (47%), Gaps = 1/121 (0%) Query: 4 KKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRK 63 K++++ + +++ +++ EK + + + E + + KEE+ K + Sbjct: 839 KRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPER 898 Query: 64 RKRKKKKEEEEREEEEEEEEEEKEEEE-KEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKK 122 ++ ++ EE+E +E+ ++++E+ E E R R + + E+ E + + KK Sbjct: 899 KESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAHDENKK 958 Query: 123 K 123 K Sbjct: 959 K 959 Score = 38.5 bits (88), Expect = 0.001 Identities = 18/120 (15%), Positives = 53/120 (44%), Gaps = 2/120 (1%) Query: 4 KKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRK 63 ++K+ E + + + R+ +R+E + K+ +E + R+E+E E+ + Sbjct: 383 QRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSS 442 Query: 64 RK--RKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTK 121 + R ++ + R+ + + ++ E R ++ + ++ +E + + R T+ Sbjct: 443 SRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTR 502 Score = 38.1 bits (87), Expect = 0.002 Identities = 16/107 (14%), Positives = 48/107 (44%) Query: 14 EETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEE 73 E E+T + ++E +E+R+ ++ + + + E R ++ + + R R++ ++ Sbjct: 415 ERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSR 474 Query: 74 EREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120 + + E + ++ +E + R + + + E + R+ T Sbjct: 475 DMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDT 521 Score = 38.1 bits (87), Expect = 0.002 Identities = 23/121 (19%), Positives = 52/121 (42%), Gaps = 11/121 (9%) Query: 8 KETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRK 67 ++ E+T+ E T E + + + K + +++ + +R E + + R Sbjct: 1233 RDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGS 1292 Query: 68 KKKEE--EEREEEEEEEEEEKE---------EEEKEEGRRRKKKKKRRRKEEEEEKKKKR 116 + +ER+ E + E E+E + + ++ R + + R R+ E E ++ KR Sbjct: 1293 FDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERERERERDKR 1352 Query: 117 R 117 R Sbjct: 1353 R 1353 Score = 37.7 bits (86), Expect = 0.002 Identities = 19/104 (18%), Positives = 50/104 (48%), Gaps = 2/104 (1%) Query: 11 EETEETEETEEEEEKEGKRKEKRKEK--RKEKEKKKKTKETEKRKEKEEEEKKRKRKRKK 68 + +E + E + E+E +R++ R+ + R + + ++ ++ +E+E E ++ KR+ Sbjct: 1297 DRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERERERERDKRRDLD 1356 Query: 69 KKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEK 112 ++ E + E + + + E + K+ + E E E+ Sbjct: 1357 RERERLISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGEHER 1400 Score = 37.4 bits (85), Expect = 0.003 Identities = 28/98 (28%), Positives = 44/98 (44%), Gaps = 9/98 (9%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 KK KKKKE + E E E K+ +K+K EKK+K + + EE + Sbjct: 964 KKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIEKKRKKSKGDSDISDEEAAQ 1023 Query: 61 KRKRKRKKKKEEEEREEEEEE---------EEEEKEEE 89 + K+KR + +EE E E+ +K+E+ Sbjct: 1024 QSKKKRGPRTPPITTKEELVEMCNGKNGILEDSQKKED 1061 Score = 36.6 bits (83), Expect = 0.005 Identities = 24/114 (21%), Positives = 56/114 (49%), Gaps = 3/114 (2%) Query: 5 KKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKR 64 K++++TE E + ++ + +++ R E KKK K +K +K++E+ Sbjct: 919 KQREQTEILESSRMRAQDIIGHHQSEDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGIE 978 Query: 65 KRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRR 118 + + E+ + ++ ++K+ EK +R+K K +EE ++ K++R Sbjct: 979 RGNIETTSEDGQVFSPKKGQKKKSIEK---KRKKSKGDSDISDEEAAQQSKKKR 1029 Score = 36.6 bits (83), Expect = 0.005 Identities = 21/131 (16%), Positives = 58/131 (44%), Gaps = 11/131 (8%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 K + + K E + T ++ R+ + R+ + ++ +E++ E Sbjct: 1248 KSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEH 1307 Query: 61 KRKRKRKKKKEEEEREEEEEEEEE----------EKEEEEKEEGRRRKKKKKRRRKEEEE 110 R+R+R+++ + +RE + + +++ + E E+E +RR ++R R + Sbjct: 1308 DRERERERR-DTRQREWDRDADKDWPRNRDRDRLRERERERERDKRRDLDRERERLISDS 1366 Query: 111 EKKKKRRRKTK 121 ++ + R + + Sbjct: 1367 VERDRDRDRDR 1377 Score = 35.4 bits (80), Expect = 0.011 Identities = 19/107 (17%), Positives = 58/107 (54%), Gaps = 5/107 (4%) Query: 12 ETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEE-EEKKRKRKRKKKK 70 ++ + + + E + +R+ +R++ R+ + + K+ + ++++ E++R+R+R K++ Sbjct: 1294 DSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERERERERDKRR 1353 Query: 71 E-EEERE---EEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKK 113 + + ERE + E + +++ + E + + K+ K E E ++ Sbjct: 1354 DLDRERERLISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGEHER 1400 Score = 33.5 bits (75), Expect = 0.042 Identities = 23/122 (18%), Positives = 54/122 (44%), Gaps = 4/122 (3%) Query: 6 KKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRK----EKEEEEKK 61 KK+ + E ++ + ++ + KRK K KK ++T +++ K Sbjct: 194 KKEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRNSKT 253 Query: 62 RKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTK 121 + K+K + E+ K+ +EK + + R ++K R K+ + +++R ++ K Sbjct: 254 NQSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRIEEKTRDGKDRGRDFERQREKRDK 313 Query: 122 KK 123 + Sbjct: 314 PR 315 Score = 32.7 bits (73), Expect = 0.071 Identities = 20/67 (29%), Positives = 37/67 (55%), Gaps = 4/67 (5%) Query: 2 KKKKKKKETEETEETE----ETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEE 57 +KK KK+ E+ E ET E+ + K+ +K+K EK++KK +++ E+ Sbjct: 963 QKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIEKKRKKSKGDSDISDEEAA 1022 Query: 58 EEKKRKR 64 ++ K+KR Sbjct: 1023 QQSKKKR 1029 Score = 32.7 bits (73), Expect = 0.071 Identities = 16/103 (15%), Positives = 47/103 (45%), Gaps = 3/103 (2%) Query: 24 EKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEE---REEEEE 80 + + RK +++EK K + T +RK + ++ K+ + R + ++ Sbjct: 1219 DDQSGRKRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRS 1278 Query: 81 EEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123 E +++ + + + + R + E + ++++ RR T+++ Sbjct: 1279 SPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQR 1321 Score = 32.3 bits (72), Expect = 0.093 Identities = 23/118 (19%), Positives = 49/118 (41%), Gaps = 5/118 (4%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 +++ + ++ ++ E + + ++ ++ R + + ++ ++T RKE E+ Sbjct: 467 RRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTH-RKEDTYPEE 525 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRR 118 R R +EE R E E E + E R + + R R E EK + R Sbjct: 526 SRSYGRNHLREESSR----TEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSR 579 Score = 32.0 bits (71), Expect = 0.12 Identities = 33/197 (16%), Positives = 69/197 (35%), Gaps = 79/197 (40%) Query: 6 KKKETEETEETEETEEEEEK---------EGKRKEKRKEKRKEK---------------- 40 + +E +T E+T EE + E R E R E R E Sbjct: 508 RDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRV 567 Query: 41 -----------------------------EKKKKTKETEKRKEKEEEEKKR--------- 62 E + E ++ E++ ++ R Sbjct: 568 PELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHG 627 Query: 63 KRKRKKKKEEEER----------------EEEEEEEEEEKEEEEKEEGRRRKKKKKRRRK 106 +R R+ +E ++R +E EE ++ ++ ++E R + +++ R + Sbjct: 628 ERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDR 687 Query: 107 EEEEEKKKKRRRKTKKK 123 E E E++++R R+ +K+ Sbjct: 688 ERERERERERDREREKE 704 Score = 30.0 bits (66), Expect = 0.46 Identities = 21/104 (20%), Positives = 45/104 (43%), Gaps = 7/104 (6%) Query: 3 KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKR 62 K K+K + ++ + + + ++ K + KKK T E+ Sbjct: 217 KSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRNSKTNQSKKKGPRTPSPPPPIPEDIAL 276 Query: 63 KRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRK 106 +K K+K + ++R EEK + K+ GR ++++++R K Sbjct: 277 GKKYKEKYKVKDR-------IEEKTRDGKDRGRDFERQREKRDK 313 Score = 29.6 bits (65), Expect = 0.60 Identities = 22/102 (21%), Positives = 45/102 (44%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 KK K +KK ++ +E + E E ++ + K+ +KKK ++ K+ + + + Sbjct: 958 KKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIEKKRKKSKGDSDIS 1017 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKK 102 + ++ KK+ R +EE E + G +KK Sbjct: 1018 DEEAAQQSKKKRGPRTPPITTKEELVEMCNGKNGILEDSQKK 1059 Score = 29.3 bits (64), Expect = 0.79 Identities = 20/127 (15%), Positives = 53/127 (41%), Gaps = 11/127 (8%) Query: 1 KKKKKKKKETEETEETEETEEE-----------EEKEGKRKEKRKEKRKEKEKKKKTKET 49 +++++++++T + E + +++ E + + ++KR++ +E+E+ Sbjct: 1309 RERERERRDTRQREWDRDADKDWPRNRDRDRLRERERERERDKRRDLDRERERLISDSVE 1368 Query: 50 EKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEE 109 R + + + K+ E + E E E + E + + R K + E Sbjct: 1369 RDRDRDRDRTFESSQIESVKRCEAKLEGEHERDLESTSRDSLALDKERMDKDLGSVQGFE 1428 Query: 110 EEKKKKR 116 E K +R Sbjct: 1429 ETNKSER 1435 Score = 28.5 bits (62), Expect = 1.3 Identities = 17/99 (17%), Positives = 45/99 (45%), Gaps = 5/99 (5%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEE--- 58 K K+K + + +++ + ++++ + + KKK + E+ Sbjct: 217 KSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRNSKTNQSKKKGPRTPSPPPPIPEDIAL 276 Query: 59 --EKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGR 95 + K K K K + EE+ R+ ++ + E++ E++++ R Sbjct: 277 GKKYKEKYKVKDRIEEKTRDGKDRGRDFERQREKRDKPR 315 Score = 27.3 bits (59), Expect = 3.0 Identities = 26/115 (22%), Positives = 47/115 (40%), Gaps = 22/115 (19%) Query: 22 EEEKEGKRKE--KRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRK-----RKKKKEEEE 74 E+E KR+E +KE E + K + RK + ++K K +K +K Sbjct: 181 EQENMEKREEIIIKKEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAV 240 Query: 75 REEEEEEEEEEKEEEEKEEGRR---------------RKKKKKRRRKEEEEEKKK 114 +++ K + K++G R +K K+K + K+ EEK + Sbjct: 241 SSPLLDQQRNSKTNQSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRIEEKTR 295 Score = 27.3 bits (59), Expect = 3.0 Identities = 14/88 (15%), Positives = 40/88 (45%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 K KK+ + + + +++ + K+K R ++ K+ +E+ K Sbjct: 226 KSSSASKKDRKTSAVSSPLLDQQRNSKTNQSKKKGPRTPSPPPPIPEDIALGKKYKEKYK 285 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEE 88 + R +K ++ ++R + E + E++++ Sbjct: 286 VKDRIEEKTRDGKDRGRDFERQREKRDK 313 >gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] Length = 202 Score = 87.0 bits (214), Expect = 3e-18 Identities = 41/136 (30%), Positives = 82/136 (60%), Gaps = 13/136 (9%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKR-----KEKRKEKEKKKKTKETEKRKEK 55 ++K++ ++ E E ETE + E++ +R+ KR ++K +++E+K++T +R K Sbjct: 58 RQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRK 117 Query: 56 --------EEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKE 107 E E+ R+R+R++++E E + + E + E ++E + E RKK++K+ RK+ Sbjct: 118 GGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKK 177 Query: 108 EEEEKKKKRRRKTKKK 123 E +EKKK+ +R+ KK Sbjct: 178 ERKEKKKEEKRREDKK 193 Score = 84.7 bits (208), Expect = 2e-17 Identities = 34/125 (27%), Positives = 82/125 (65%), Gaps = 2/125 (1%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 K+++++K+ + + ETE E E++ +R+ +R+ KR+ ++ K ++ E+++E + + Sbjct: 54 KERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRE 113 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKK--KKRRRKEEEEEKKKKRRR 118 + ++ +++ ++ ERE + E E + + E E++ R RK++ ++R+R E EE+KK+R++ Sbjct: 114 RNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKK 173 Query: 119 KTKKK 123 + KK+ Sbjct: 174 ERKKE 178 Score = 83.2 bits (204), Expect = 5e-17 Identities = 33/123 (26%), Positives = 81/123 (65%), Gaps = 2/123 (1%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 ++ +++++ + E +T+ E +K+ R+ KR+ R + +K +E +K+ E+E + + Sbjct: 74 RETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRE 133 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120 + ++++++++ + +RE + E + E + E+EE + K++KK R+KE +E+KK+++RR+ Sbjct: 134 RERQRQRERERQRQRERKRETDRERQRWAEREERK--KERKKERKKERKEKKKEEKRRED 191 Query: 121 KKK 123 KK+ Sbjct: 192 KKR 194 Score = 81.6 bits (200), Expect = 1e-16 Identities = 29/119 (24%), Positives = 82/119 (68%), Gaps = 1/119 (0%) Query: 1 KKKKKKKKETEETEETE-ETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEE 59 +++++++++ E +T+ E +++ ++E KR+ R +R K +++ K+TE+ +++E E Sbjct: 77 ERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERER 136 Query: 60 KKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRR 118 ++++ + ++++ E +RE + E + + EE K+E ++ +KK+++ +K+EE+ ++ K+R+ Sbjct: 137 QRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDKKRK 195 Score = 74.7 bits (182), Expect = 2e-14 Identities = 36/146 (24%), Positives = 87/146 (59%), Gaps = 23/146 (15%) Query: 1 KKKKKKKKETEETEETE-------ETEEEEEKEGKRK--------------EKRKEKRKE 39 ++++++K+ET+ +ETE E E + E+E + + EK +E++KE Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61 Query: 40 KEKKK-KTKETEKRKEKEEE-EKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRR 97 +++++ + +ETE+ E++ E +++R+RKR+ +E ++ + E + E ++ E +G R Sbjct: 62 RDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRE 121 Query: 98 KKKKKRRRKEEEEEKKKKRRRKTKKK 123 + K+ R ++ E E++++R R+ +++ Sbjct: 122 RDKQTERERDRERERQRQRERERQRQ 147 Score = 62.0 bits (149), Expect = 1e-10 Identities = 24/100 (24%), Positives = 67/100 (67%), Gaps = 7/100 (7%) Query: 2 KKKKKKKETEETEETE-------ETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKE 54 + +++K+ET+ E + + E E++ +R+ +R+ +R+ + ++++ +ET++ ++ Sbjct: 100 RDRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQ 159 Query: 55 KEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEG 94 + E ++RK++RKK++++E +E+++EE+ E ++ + EG Sbjct: 160 RWAEREERKKERKKERKKERKEKKKEEKRREDKKRKWGEG 199 Score = 59.3 bits (142), Expect = 7e-10 Identities = 23/104 (22%), Positives = 67/104 (64%), Gaps = 11/104 (10%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKK-KTKETEKRKEKEEEEK 60 +++ K ++ E ET+ E K G+ ++K+ E+ +++E+++ + +E E+++++E + + Sbjct: 94 RERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRE 153 Query: 61 ----------KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEG 94 + +RK+++KKE ++ +E+++EE+ +E+++++ G Sbjct: 154 TDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDKKRKWG 197 Score = 40.4 bits (93), Expect = 3e-04 Identities = 19/50 (38%), Positives = 35/50 (70%), Gaps = 2/50 (4%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGK--RKEKRKEKRKEKEKKKKTKE 48 ++K++ +E + E EE ++E +KE K RKEK+KE+++ ++KK+K E Sbjct: 149 ERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDKKRKWGE 198 >gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo sapiens] Length = 600 Score = 87.0 bits (214), Expect = 3e-18 Identities = 36/122 (29%), Positives = 80/122 (65%), Gaps = 1/122 (0%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 + ++K+++ + +E E E + EKE K +++ E+ +E+E++++T+ +RK + + E+ Sbjct: 173 RNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRER 232 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120 R+RK ++++E++ E E E E+++E + E R R + + RR+KE E + +KR+R+T Sbjct: 233 DRQRKTEREREKQAERERASERETERDKERERE-RDRDRDRDRRQKERERQTDRKRQRRT 291 Query: 121 KK 122 ++ Sbjct: 292 ER 293 Score = 86.3 bits (212), Expect = 5e-18 Identities = 39/126 (30%), Positives = 81/126 (64%), Gaps = 4/126 (3%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 +K++++++ E E ETE + EKE +RK KR + ++E+ ++T +R+ + E E+ Sbjct: 315 RKRERERERERERERQRETERDREKERERKRKR-QTEMDRERNRQTGREGRRQAERERER 373 Query: 61 KRKRKRKKKKEEEERE---EEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRR 117 +R+R R+ +E EERE + + ++E E++ E+ +G+R +K++ R K+ E E+ ++R Sbjct: 374 ERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERG 433 Query: 118 RKTKKK 123 R+ +K+ Sbjct: 434 REREKQ 439 Score = 85.5 bits (210), Expect = 9e-18 Identities = 39/126 (30%), Positives = 85/126 (67%), Gaps = 3/126 (2%) Query: 1 KKKKKKKKETEETEETE-ETEEEEEKEGKRKEKRKEKRKEKEKKKKT-KETEKRKEKEEE 58 K +++++K+ E +E ETE ++E+E +R R R++KE++++T ++ ++R E++ E Sbjct: 237 KTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRE 296 Query: 59 -EKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRR 117 E+KR+R+R++++E E + E E E E+E E + E R ++K++ R+++ + E ++R Sbjct: 297 TERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERN 356 Query: 118 RKTKKK 123 R+T ++ Sbjct: 357 RQTGRE 362 Score = 85.1 bits (209), Expect = 1e-17 Identities = 38/126 (30%), Positives = 78/126 (61%), Gaps = 6/126 (4%) Query: 4 KKKKKETEETEETEETEEEEEKEGKRK---EKRKEKRKEKEKKKKTKETEKRKEKEEE-- 58 ++K++ E + +TE E EK+ +R+ E+ E+ KE+E+++ R++KE E Sbjct: 223 ERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQ 282 Query: 59 -EKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRR 117 ++KR+R+ ++ +E E + E + E E E+E K E R +++++ R++E E +++K+R Sbjct: 283 TDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERE 342 Query: 118 RKTKKK 123 RK K++ Sbjct: 343 RKRKRQ 348 Score = 84.7 bits (208), Expect = 2e-17 Identities = 32/122 (26%), Positives = 76/122 (62%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 +K++++ + ETE E + E E+E +R KR+ +R+ + ++++ +ETE+ +EKE E K Sbjct: 285 RKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERK 344 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120 ++++ ++ + E + E + E E+E R+ ++++ R ++ + +++K+R R+T Sbjct: 345 RKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQT 404 Query: 121 KK 122 +K Sbjct: 405 EK 406 Score = 83.2 bits (204), Expect = 5e-17 Identities = 37/141 (26%), Positives = 84/141 (59%), Gaps = 18/141 (12%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKK-----KTKETEKRKEK 55 K+ ++++ ETE +E E E +++ R ++KE+ ++ ++K+ + +ETE+++E+ Sbjct: 244 KQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRER 303 Query: 56 EEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKK-------------KKK 102 + E ++ + + +K++ E ERE E E + E + + EKE R+RK+ ++ Sbjct: 304 QRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREG 363 Query: 103 RRRKEEEEEKKKKRRRKTKKK 123 RR+ E E E++++R R++ ++ Sbjct: 364 RRQAERERERERERDRQSARE 384 Score = 81.3 bits (199), Expect = 2e-16 Identities = 34/122 (27%), Positives = 79/122 (64%), Gaps = 2/122 (1%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKR-KEKRKEKRKEKEKKKKTKETEKRKEKEEEE 59 +++ +++K E E+ E E E+E +R KE+ +E+ +++++ ++ KE E++ +++ + Sbjct: 230 RERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQR 289 Query: 60 KKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRK 119 + + + ++K E +RE E E E K E E+E R R+++++ R + E+E+++KR+R+ Sbjct: 290 RTERDRETERKRERQRERERERERNRKRERERERERERERQRETER-DREKERERKRKRQ 348 Query: 120 TK 121 T+ Sbjct: 349 TE 350 Score = 79.7 bits (195), Expect = 5e-16 Identities = 34/128 (26%), Positives = 81/128 (63%), Gaps = 5/128 (3%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKT--KETEKRKEKEEE 58 K ++++++ + E+ +TE+ + G+ +E+ +E E E+K++T + +RK + E Sbjct: 183 KNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTERER 242 Query: 59 EKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEE---EEEKKKK 115 EK+ +R+R ++E E +E E E + +++ + +++ R R+ +KR+R+ E E E+K++ Sbjct: 243 EKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRE 302 Query: 116 RRRKTKKK 123 R+R+ +++ Sbjct: 303 RQRERERE 310 Score = 78.2 bits (191), Expect = 1e-15 Identities = 34/136 (25%), Positives = 78/136 (57%), Gaps = 13/136 (9%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 +K++++++E +TE + + E +E R KR R+ + ++K +E + +E++ + + Sbjct: 59 QKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQRE 118 Query: 61 KRKRKRKKKKEEEERE-------------EEEEEEEEEKEEEEKEEGRRRKKKKKRRRKE 107 K + ++K+++ E ERE E E + + EKE E + + R+++ ++ R+KE Sbjct: 119 KERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKE 178 Query: 108 EEEEKKKKRRRKTKKK 123 E EK ++ RR+ +++ Sbjct: 179 REREKNRQERRERERQ 194 Score = 78.2 bits (191), Expect = 1e-15 Identities = 37/130 (28%), Positives = 77/130 (59%), Gaps = 8/130 (6%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKE---- 56 +++K+ K E +E E E E E E + + KR+ R+ ++K +E EK+ E+E Sbjct: 194 QREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASE 253 Query: 57 ---EEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKK 113 E +K+R+R+R + ++ + R++E E + + K + E R ++K++R+R E E E++ Sbjct: 254 RETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQR-ERERERE 312 Query: 114 KKRRRKTKKK 123 + R+R+ +++ Sbjct: 313 RNRKRERERE 322 Score = 78.2 bits (191), Expect = 1e-15 Identities = 34/123 (27%), Positives = 79/123 (64%), Gaps = 4/123 (3%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 ++K++++K +TE E + +EG+R+ +R+ +R+ + ++ +E E+R+ + ++ Sbjct: 337 REKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDR 396 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEE---KEEGRRRKKKKKRRR-KEEEEEKKKKR 116 +++R+R+ +K+ + + E E++ E EK+ E +E GR R+K+K R R +E + +++ R Sbjct: 397 QKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGR 456 Query: 117 RRK 119 +RK Sbjct: 457 QRK 459 Score = 77.0 bits (188), Expect = 3e-15 Identities = 30/122 (24%), Positives = 79/122 (64%), Gaps = 1/122 (0%) Query: 3 KKKKKKETEETEETEETEEEEEKEGKR-KEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61 +++ ++ +E +E E E E+EG+R ++++ + ++E+E+++ ++ +R+ E +++ Sbjct: 111 RERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQ 170 Query: 62 RKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTK 121 +R R+K++E E+ +E E E ++E+E K E R ++ ++R R+ E E + +++R+ + Sbjct: 171 TERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDR 230 Query: 122 KK 123 ++ Sbjct: 231 ER 232 Score = 76.6 bits (187), Expect = 4e-15 Identities = 40/144 (27%), Positives = 84/144 (58%), Gaps = 21/144 (14%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKR-KEKRKEKRKEKEK---KKKTKETEKRKEKE 56 K++ ++K+ ETE E + + +G+R +E++++ KE+E+ +++ ++TE+ ++KE Sbjct: 119 KERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKE 178 Query: 57 EEEKK-----RKRKRKKKKE------------EEEREEEEEEEEEEKEEEEKEEGRRRKK 99 E +K R+R+R+++KE E ERE E E E E K + ++E R+RK Sbjct: 179 REREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKT 238 Query: 100 KKKRRRKEEEEEKKKKRRRKTKKK 123 +++R ++ E E ++ + K++ Sbjct: 239 EREREKQAERERASERETERDKER 262 Score = 74.7 bits (182), Expect = 2e-14 Identities = 34/137 (24%), Positives = 84/137 (61%), Gaps = 15/137 (10%) Query: 1 KKKKKKKKETE-ETEETEETEEEEEKEGKRKEKRKEKR-KEKEKKKKTKETEKRKEKEEE 58 ++++++K++TE ET+ E E+++ KR R+ +R +EKE++++T R+ ++E Sbjct: 62 RERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKER 121 Query: 59 EKKRKRKRKKKKE-------------EEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRR 105 ++++R+R+ ++E E ER+ + E+E E + + E++ R ++K+R R Sbjct: 122 NRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKERER 181 Query: 106 KEEEEEKKKKRRRKTKK 122 ++ +E++++ R++ K+ Sbjct: 182 EKNRQERRERERQREKE 198 Score = 72.8 bits (177), Expect = 6e-14 Identities = 28/122 (22%), Positives = 73/122 (59%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 ++++++K + + E + + EKE +R+ R+ R+ ++++ + KE E+ E+E E Sbjct: 79 RERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERG 138 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120 + ++ +++ E +R+ E+E E + E +++ R R+K+++R + +E +++++R K Sbjct: 139 RDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKE 198 Query: 121 KK 122 K Sbjct: 199 NK 200 Score = 72.4 bits (176), Expect = 8e-14 Identities = 31/121 (25%), Positives = 74/121 (61%), Gaps = 4/121 (3%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEK---EKKKKTKETEKRKEKEEE 58 +++++++ E E +T+ E +++ +R ++KE+ +EK E++++ ++ EK + E+ Sbjct: 146 QRERERQRDAEKERERQTDRERQRQTERN-RQKEREREKNRQERRERERQREKENKTEDR 204 Query: 59 EKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRR 118 +R R+R++++E E E + + + E++ + K E R K+ ++ R E E E+ K+R R Sbjct: 205 HSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERER 264 Query: 119 K 119 + Sbjct: 265 E 265 Score = 70.5 bits (171), Expect = 3e-13 Identities = 29/124 (23%), Positives = 73/124 (58%), Gaps = 3/124 (2%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKT---KETEKRKEKEE 57 ++ ++K++E + E + E+E K +E+ E+ E+ + ++T +E E++++ E+ Sbjct: 98 QRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEK 157 Query: 58 EEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRR 117 E +++ + ++++ E R++E E E+ +E E+E R ++ K + R E E++++R Sbjct: 158 ERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERE 217 Query: 118 RKTK 121 +T+ Sbjct: 218 TETE 221 Score = 67.8 bits (164), Expect = 2e-12 Identities = 27/116 (23%), Positives = 68/116 (58%), Gaps = 1/116 (0%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61 +++ +E+ + ++ + + + + ++KE+ + +EK++ +ET++++E+ EK Sbjct: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRER-RREKD 86 Query: 62 RKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRR 117 R RKR + +E + E+E E + ++E + + E R ++K++ R E E E+ + R+ Sbjct: 87 RHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQ 142 Score = 67.8 bits (164), Expect = 2e-12 Identities = 26/120 (21%), Positives = 70/120 (58%), Gaps = 2/120 (1%) Query: 6 KKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRK 65 K + ++ E + E E +E ++ E+ ++++E+ ++K R + + +++++R+ Sbjct: 47 KDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERE 106 Query: 66 RKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKK--RRRKEEEEEKKKKRRRKTKKK 123 R+ +E + + E+E ++E+E E + EG R + ++ +R +E + + +K+R R+T ++ Sbjct: 107 RQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRE 166 Score = 67.8 bits (164), Expect = 2e-12 Identities = 29/126 (23%), Positives = 75/126 (59%), Gaps = 4/126 (3%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKR---KEKRKEKRKEKEKKKKTKETEKRKEKEE 57 ++K + +K E + E+E E++ R +++ KE+ ++KE++++T+ +R + Sbjct: 83 REKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQ 142 Query: 58 EEKKRKRKRKKKKEEE-EREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKR 116 + +R+R+R++ E+E ER+ + E + + + +KE R + ++++R R+ + E++ K Sbjct: 143 TDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTE 202 Query: 117 RRKTKK 122 R +++ Sbjct: 203 DRHSER 208 Score = 65.9 bits (159), Expect = 8e-12 Identities = 28/130 (21%), Positives = 75/130 (57%), Gaps = 16/130 (12%) Query: 9 ETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKK 68 + + + ++ E +KE +R+ ++++ +E ++K++ + + R K + ++R+R R+K Sbjct: 44 QAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREK 103 Query: 69 KKE---EEEREEEEEEEEEEKEEEEKE-------------EGRRRKKKKKRRRKEEEEEK 112 ++E + ER+ + E+E ++E E+E +G+R +++++ KE E + Sbjct: 104 ERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQT 163 Query: 113 KKKRRRKTKK 122 ++R+R+T++ Sbjct: 164 DRERQRQTER 173 Score = 60.8 bits (146), Expect = 2e-10 Identities = 23/93 (24%), Positives = 61/93 (65%), Gaps = 2/93 (2%) Query: 31 EKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEE 90 + K+ + ++ + KE E+R+EK + E++ RKR++++E++ + + E +++ E+ Sbjct: 44 QAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREK 103 Query: 91 KEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123 + E R+ +++ R++E+E ++K+R R+T+++ Sbjct: 104 ERE--RQTDRERDRQREKERNRQKERERETERE 134 Score = 27.3 bits (59), Expect = 3.0 Identities = 11/48 (22%), Positives = 31/48 (64%), Gaps = 1/48 (2%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKET 49 +K++++++ E+E E E EK+ K +E+ +E++ +++ ++ K + Sbjct: 415 EKQREREKDRESERGRERGREREKQ-KGRERDRERQTDRQAGRQRKRS 461 >gi|116089325 splicing factor, arginine/serine-rich 12 isoform a [Homo sapiens] Length = 624 Score = 86.7 bits (213), Expect = 4e-18 Identities = 43/133 (32%), Positives = 81/133 (60%), Gaps = 11/133 (8%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 +K++ K+K+ E+ E E+ E+E++ GK K++ KE+ K++EK K+ K+ E+ +EKE E+ Sbjct: 386 EKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKE-KDREREREKEHEKD 444 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKE----------EGRRRKKKKKRRRKEEEE 110 + K K K++ +E+ERE++ +E +EK +++K+ R R ++RRR+ Sbjct: 445 RDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRS 504 Query: 111 EKKKKRRRKTKKK 123 + R KT K+ Sbjct: 505 SSRSPRTSKTIKR 517 Score = 85.5 bits (210), Expect = 9e-18 Identities = 42/128 (32%), Positives = 81/128 (63%), Gaps = 8/128 (6%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEK-KKKTKETEKRKEKEEE- 58 K KK+ ++ E ++ +K +EK KEK + KEK ++K +E EK +EKE+E Sbjct: 352 KSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKER 411 Query: 59 ------EKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEK 112 +K+R++ R+K KE++ E E+E E+++++E+++E + K+++K R KE +E++ Sbjct: 412 GKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKR 471 Query: 113 KKKRRRKT 120 KK ++ +T Sbjct: 472 KKDKKSRT 479 Score = 83.2 bits (204), Expect = 5e-17 Identities = 44/125 (35%), Positives = 77/125 (61%), Gaps = 3/125 (2%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEK-KKKTKETEKRKEKEEEE 59 ++ K K+ ++ E ++ KRK+ R EK KEKE+ K+K +E E+ +EKE E+ Sbjct: 349 RRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTR-EKIKEKERVKEKDREKEREREKEREK 407 Query: 60 KKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKE-EGRRRKKKKKRRRKEEEEEKKKKRRR 118 +K + K K + +E E++ E+++E++ + E EKE E R K+K+K + KE+E EK + + Sbjct: 408 EKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEI 467 Query: 119 KTKKK 123 K+K Sbjct: 468 DEKRK 472 Score = 82.8 bits (203), Expect = 6e-17 Identities = 46/135 (34%), Positives = 84/135 (62%), Gaps = 16/135 (11%) Query: 3 KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKK-KTKETEKRKEKEEEEKK 61 + K+K E+ +E E +E++ ++ + +EK +EK KE+ K K + KE EK +EK ++EK Sbjct: 374 RDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREK-DKEKD 432 Query: 62 RKRKRKKKKEEEEREEEEEEEEEEKEEEE---KEEGRRRKKKKK-----------RRRKE 107 R+R+R+K+ E++ +E+E+E+++EKE E+ KE +RKK KK RR + Sbjct: 433 REREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRS 492 Query: 108 EEEEKKKKRRRKTKK 122 E++++R R + + Sbjct: 493 SSRERRRRRSRSSSR 507 Score = 78.6 bits (192), Expect = 1e-15 Identities = 32/124 (25%), Positives = 79/124 (63%), Gaps = 2/124 (1%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61 + ++K + ++ + ++ E ++ + + ++KRK+ +K K KE K K++E+E ++ Sbjct: 342 RSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKERER 401 Query: 62 RKRKRKKKK--EEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRK 119 K + K+K+ + ++R++E E++ E+ +E+++E R ++ +K R +++E+E+ K+K R K Sbjct: 402 EKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREK 461 Query: 120 TKKK 123 + K Sbjct: 462 DRSK 465 Score = 74.3 bits (181), Expect = 2e-14 Identities = 37/128 (28%), Positives = 74/128 (57%), Gaps = 5/128 (3%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEK-KKKTKETEKRKEKEEEE 59 + K + ++ + +++ + + ++K++R+ K KK++K E+RK + Sbjct: 313 RSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSH 372 Query: 60 KKRKRK--RKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKK--KKRRRKEEEEEKKKK 115 + KRK R+K KE+E +E++ E+E E+E+E ++E R K K K R K+ E++K+K Sbjct: 373 SRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKD 432 Query: 116 RRRKTKKK 123 R R+ +K+ Sbjct: 433 REREREKE 440 Score = 67.8 bits (164), Expect = 2e-12 Identities = 34/134 (25%), Positives = 68/134 (50%), Gaps = 11/134 (8%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEK---KKKTKETEKRKEKEE 57 +K+++K+KE + ++ ++ E++ ++ K K++ +E+ KE EK K+K KE +K KE+E+ Sbjct: 402 EKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREK 461 Query: 58 EEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKR--------RRKEEE 109 + K +++KK ++ +E RRR + R +RK Sbjct: 462 DRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSR 521 Query: 110 EEKKKKRRRKTKKK 123 + R +K KK+ Sbjct: 522 SPSPRSRNKKDKKR 535 Score = 63.2 bits (152), Expect = 5e-11 Identities = 25/125 (20%), Positives = 70/125 (56%), Gaps = 2/125 (1%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 + + + ++ + ++ + + + + + + + ++K++++ +KR + E K Sbjct: 307 RSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRK 366 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGR--RRKKKKKRRRKEEEEEKKKKRRR 118 R R + K ++ RE+ +E+E ++++ EKE R R+K+K+R + ++ +++++K R Sbjct: 367 SRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDRE 426 Query: 119 KTKKK 123 K K+K Sbjct: 427 KDKEK 431 Score = 63.2 bits (152), Expect = 5e-11 Identities = 35/143 (24%), Positives = 71/143 (49%), Gaps = 24/143 (16%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKE-KEKKKKTKET---------EK 51 K+K +++E E+ E + +E+E+++ K KE+ K++ KE EK+KK K++ + Sbjct: 429 KEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASR 488 Query: 52 RKEKEEEEKKRKR--------------KRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRR 97 R E++R+R KRK + R +++++ EKE + E R R Sbjct: 489 RSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRER 548 Query: 98 KKKKKRRRKEEEEEKKKKRRRKT 120 ++ R+ + + K+K + + Sbjct: 549 ERSTSMRKSSNDRDGKEKLEKNS 571 Score = 53.9 bits (128), Expect = 3e-08 Identities = 26/115 (22%), Positives = 54/115 (46%), Gaps = 11/115 (9%) Query: 20 EEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEE 79 E E K +RK R + + +K +RK + + + R R + ++++ R + Sbjct: 294 EPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKS 353 Query: 80 EEEEEEKEEE-----------EKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123 ++ K E +K + R K K+K R KE++ EK+++R ++ +K+ Sbjct: 354 PHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKE 408 Score = 50.8 bits (120), Expect = 3e-07 Identities = 20/115 (17%), Positives = 54/115 (46%) Query: 9 ETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKK 68 E+ ++ E + K + K + K + K + + + ++ +R+ K Sbjct: 296 ESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPH 355 Query: 69 KKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123 KK + RE + ++ K+ + K+K++ + K+ E+E+++++ R+ +K+ Sbjct: 356 KKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKE 410 Score = 50.4 bits (119), Expect = 3e-07 Identities = 29/129 (22%), Positives = 59/129 (45%), Gaps = 17/129 (13%) Query: 1 KKKKKKKKETEETEETEETEEE-----------EEKEGKRKEKRKEKRKEKEKKKKTKET 49 K+K+++K ++E +E + +++ +E+R+ + + + +T +T Sbjct: 455 KEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKT 514 Query: 50 EKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEE-----KEEEEKEEGRRRKKKKKRR 104 KRK R R +K KK E+ER+ E E E ++ +G+ + +K Sbjct: 515 IKRK-SSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTS 573 Query: 105 RKEEEEEKK 113 KE+E K+ Sbjct: 574 LKEKEHNKE 582 Score = 41.2 bits (95), Expect = 2e-04 Identities = 28/137 (20%), Positives = 56/137 (40%), Gaps = 20/137 (14%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKE--------------KRKEKRKEKEKKKKT 46 +KK KK + + +E +R+ KRK R + + Sbjct: 471 RKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNK 530 Query: 47 KETEKRKEKE--EEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRR 104 K+ ++ KE++ E ++R+R +K +R+ +E+ E+ +EKE K+ Sbjct: 531 KDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKE----HNKEPDSS 586 Query: 105 RKEEEEEKKKKRRRKTK 121 +E ++K R + K Sbjct: 587 VSKEVDDKDAPRTEENK 603 Score = 38.5 bits (88), Expect = 0.001 Identities = 29/96 (30%), Positives = 41/96 (42%), Gaps = 11/96 (11%) Query: 1 KKKKKKKKETEETEETEETE-------EEEEKEGKRK-EKRKEKRKEKEKKKKTKETEKR 52 KK KK++KE + E E E +++GK K EK KEKE KE + Sbjct: 530 KKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKE---HNKEPDSS 586 Query: 53 KEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEE 88 KE ++K R + K + + EE K E Sbjct: 587 VSKEVDDKDAPRTEENKIQHNGNCQLNEENLSTKTE 622 Score = 36.6 bits (83), Expect = 0.005 Identities = 16/107 (14%), Positives = 47/107 (43%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61 K+K + + + ++ + E+E++ + + +E+ K ++ +++ EK K Sbjct: 516 KRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLK 575 Query: 62 RKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEE 108 K K+ +E ++++ +E + + G + ++ K E Sbjct: 576 EKEHNKEPDSSVSKEVDDKDAPRTEENKIQHNGNCQLNEENLSTKTE 622 Score = 32.3 bits (72), Expect = 0.093 Identities = 19/103 (18%), Positives = 42/103 (40%), Gaps = 3/103 (2%) Query: 22 EEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK--RKRKRKKKKEEEEREEEE 79 E + KE + ++ +E + + + + E+K R R + K + Sbjct: 265 EMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHS 324 Query: 80 EEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKK 122 + + + + R R ++K RRR + KK+ + R+ +K Sbjct: 325 RRKRSQSKHRSRSHNRSRSRQKDRRRSKSPH-KKRSKSRERRK 366 >gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [Homo sapiens] Length = 508 Score = 86.7 bits (213), Expect = 4e-18 Identities = 43/133 (32%), Positives = 81/133 (60%), Gaps = 11/133 (8%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 +K++ K+K+ E+ E E+ E+E++ GK K++ KE+ K++EK K+ K+ E+ +EKE E+ Sbjct: 270 EKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKE-KDREREREKEHEKD 328 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKE----------EGRRRKKKKKRRRKEEEE 110 + K K K++ +E+ERE++ +E +EK +++K+ R R ++RRR+ Sbjct: 329 RDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRS 388 Query: 111 EKKKKRRRKTKKK 123 + R KT K+ Sbjct: 389 SSRSPRTSKTIKR 401 Score = 85.5 bits (210), Expect = 9e-18 Identities = 42/128 (32%), Positives = 81/128 (63%), Gaps = 8/128 (6%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEK-KKKTKETEKRKEKEEE- 58 K KK+ ++ E ++ +K +EK KEK + KEK ++K +E EK +EKE+E Sbjct: 236 KSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKER 295 Query: 59 ------EKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEK 112 +K+R++ R+K KE++ E E+E E+++++E+++E + K+++K R KE +E++ Sbjct: 296 GKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKR 355 Query: 113 KKKRRRKT 120 KK ++ +T Sbjct: 356 KKDKKSRT 363 Score = 83.2 bits (204), Expect = 5e-17 Identities = 44/125 (35%), Positives = 77/125 (61%), Gaps = 3/125 (2%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEK-KKKTKETEKRKEKEEEE 59 ++ K K+ ++ E ++ KRK+ R EK KEKE+ K+K +E E+ +EKE E+ Sbjct: 233 RRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTR-EKIKEKERVKEKDREKEREREKEREK 291 Query: 60 KKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKE-EGRRRKKKKKRRRKEEEEEKKKKRRR 118 +K + K K + +E E++ E+++E++ + E EKE E R K+K+K + KE+E EK + + Sbjct: 292 EKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEI 351 Query: 119 KTKKK 123 K+K Sbjct: 352 DEKRK 356 Score = 82.8 bits (203), Expect = 6e-17 Identities = 46/135 (34%), Positives = 84/135 (62%), Gaps = 16/135 (11%) Query: 3 KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKK-KTKETEKRKEKEEEEKK 61 + K+K E+ +E E +E++ ++ + +EK +EK KE+ K K + KE EK +EK ++EK Sbjct: 258 RDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREK-DKEKD 316 Query: 62 RKRKRKKKKEEEEREEEEEEEEEEKEEEE---KEEGRRRKKKKK-----------RRRKE 107 R+R+R+K+ E++ +E+E+E+++EKE E+ KE +RKK KK RR + Sbjct: 317 REREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRS 376 Query: 108 EEEEKKKKRRRKTKK 122 E++++R R + + Sbjct: 377 SSRERRRRRSRSSSR 391 Score = 78.6 bits (192), Expect = 1e-15 Identities = 32/124 (25%), Positives = 79/124 (63%), Gaps = 2/124 (1%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61 + ++K + ++ + ++ E ++ + + ++KRK+ +K K KE K K++E+E ++ Sbjct: 226 RSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKERER 285 Query: 62 RKRKRKKKK--EEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRK 119 K + K+K+ + ++R++E E++ E+ +E+++E R ++ +K R +++E+E+ K+K R K Sbjct: 286 EKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREK 345 Query: 120 TKKK 123 + K Sbjct: 346 DRSK 349 Score = 74.3 bits (181), Expect = 2e-14 Identities = 37/128 (28%), Positives = 74/128 (57%), Gaps = 5/128 (3%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEK-KKKTKETEKRKEKEEEE 59 + K + ++ + +++ + + ++K++R+ K KK++K E+RK + Sbjct: 197 RSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSH 256 Query: 60 KKRKRK--RKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKK--KKRRRKEEEEEKKKK 115 + KRK R+K KE+E +E++ E+E E+E+E ++E R K K K R K+ E++K+K Sbjct: 257 SRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKD 316 Query: 116 RRRKTKKK 123 R R+ +K+ Sbjct: 317 REREREKE 324 Score = 67.8 bits (164), Expect = 2e-12 Identities = 34/134 (25%), Positives = 68/134 (50%), Gaps = 11/134 (8%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEK---KKKTKETEKRKEKEE 57 +K+++K+KE + ++ ++ E++ ++ K K++ +E+ KE EK K+K KE +K KE+E+ Sbjct: 286 EKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREK 345 Query: 58 EEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKR--------RRKEEE 109 + K +++KK ++ +E RRR + R +RK Sbjct: 346 DRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSR 405 Query: 110 EEKKKKRRRKTKKK 123 + R +K KK+ Sbjct: 406 SPSPRSRNKKDKKR 419 Score = 63.2 bits (152), Expect = 5e-11 Identities = 25/125 (20%), Positives = 70/125 (56%), Gaps = 2/125 (1%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 + + + ++ + ++ + + + + + + + ++K++++ +KR + E K Sbjct: 191 RSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRK 250 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGR--RRKKKKKRRRKEEEEEKKKKRRR 118 R R + K ++ RE+ +E+E ++++ EKE R R+K+K+R + ++ +++++K R Sbjct: 251 SRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDRE 310 Query: 119 KTKKK 123 K K+K Sbjct: 311 KDKEK 315 Score = 63.2 bits (152), Expect = 5e-11 Identities = 35/143 (24%), Positives = 71/143 (49%), Gaps = 24/143 (16%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKE-KEKKKKTKET---------EK 51 K+K +++E E+ E + +E+E+++ K KE+ K++ KE EK+KK K++ + Sbjct: 313 KEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASR 372 Query: 52 RKEKEEEEKKRKR--------------KRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRR 97 R E++R+R KRK + R +++++ EKE + E R R Sbjct: 373 RSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRER 432 Query: 98 KKKKKRRRKEEEEEKKKKRRRKT 120 ++ R+ + + K+K + + Sbjct: 433 ERSTSMRKSSNDRDGKEKLEKNS 455 Score = 53.9 bits (128), Expect = 3e-08 Identities = 26/115 (22%), Positives = 54/115 (46%), Gaps = 11/115 (9%) Query: 20 EEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEE 79 E E K +RK R + + +K +RK + + + R R + ++++ R + Sbjct: 178 EPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKS 237 Query: 80 EEEEEEKEEE-----------EKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123 ++ K E +K + R K K+K R KE++ EK+++R ++ +K+ Sbjct: 238 PHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKE 292 Score = 50.8 bits (120), Expect = 3e-07 Identities = 20/115 (17%), Positives = 54/115 (46%) Query: 9 ETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKK 68 E+ ++ E + K + K + K + K + + + ++ +R+ K Sbjct: 180 ESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPH 239 Query: 69 KKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123 KK + RE + ++ K+ + K+K++ + K+ E+E+++++ R+ +K+ Sbjct: 240 KKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKE 294 Score = 50.4 bits (119), Expect = 3e-07 Identities = 29/129 (22%), Positives = 59/129 (45%), Gaps = 17/129 (13%) Query: 1 KKKKKKKKETEETEETEETEEE-----------EEKEGKRKEKRKEKRKEKEKKKKTKET 49 K+K+++K ++E +E + +++ +E+R+ + + + +T +T Sbjct: 339 KEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKT 398 Query: 50 EKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEE-----KEEEEKEEGRRRKKKKKRR 104 KRK R R +K KK E+ER+ E E E ++ +G+ + +K Sbjct: 399 IKRK-SSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTS 457 Query: 105 RKEEEEEKK 113 KE+E K+ Sbjct: 458 LKEKEHNKE 466 Score = 41.2 bits (95), Expect = 2e-04 Identities = 28/137 (20%), Positives = 56/137 (40%), Gaps = 20/137 (14%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKE--------------KRKEKRKEKEKKKKT 46 +KK KK + + +E +R+ KRK R + + Sbjct: 355 RKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNK 414 Query: 47 KETEKRKEKE--EEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRR 104 K+ ++ KE++ E ++R+R +K +R+ +E+ E+ +EKE K+ Sbjct: 415 KDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKE----HNKEPDSS 470 Query: 105 RKEEEEEKKKKRRRKTK 121 +E ++K R + K Sbjct: 471 VSKEVDDKDAPRTEENK 487 Score = 38.5 bits (88), Expect = 0.001 Identities = 29/96 (30%), Positives = 41/96 (42%), Gaps = 11/96 (11%) Query: 1 KKKKKKKKETEETEETEETE-------EEEEKEGKRK-EKRKEKRKEKEKKKKTKETEKR 52 KK KK++KE + E E E +++GK K EK KEKE KE + Sbjct: 414 KKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKE---HNKEPDSS 470 Query: 53 KEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEE 88 KE ++K R + K + + EE K E Sbjct: 471 VSKEVDDKDAPRTEENKIQHNGNCQLNEENLSTKTE 506 Score = 36.6 bits (83), Expect = 0.005 Identities = 16/107 (14%), Positives = 47/107 (43%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61 K+K + + + ++ + E+E++ + + +E+ K ++ +++ EK K Sbjct: 400 KRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLK 459 Query: 62 RKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEE 108 K K+ +E ++++ +E + + G + ++ K E Sbjct: 460 EKEHNKEPDSSVSKEVDDKDAPRTEENKIQHNGNCQLNEENLSTKTE 506 Score = 32.3 bits (72), Expect = 0.093 Identities = 19/103 (18%), Positives = 42/103 (40%), Gaps = 3/103 (2%) Query: 22 EEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK--RKRKRKKKKEEEEREEEE 79 E + KE + ++ +E + + + + E+K R R + K + Sbjct: 149 EMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHS 208 Query: 80 EEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKK 122 + + + + R R ++K RRR + KK+ + R+ +K Sbjct: 209 RRKRSQSKHRSRSHNRSRSRQKDRRRSKSPH-KKRSKSRERRK 250 >gi|148746195 trichohyalin [Homo sapiens] Length = 1943 Score = 85.5 bits (210), Expect = 9e-18 Identities = 42/131 (32%), Positives = 89/131 (67%), Gaps = 8/131 (6%) Query: 1 KKKKKKKKETEETEETEETEEEEE---KEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEE 57 ++K++++++ + E E+ ++EEE +E + K +R+E+ ++ K KK ++ E++ EE Sbjct: 918 REKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEE 977 Query: 58 EEKKRKRKRKKKKEEEEREEEEEEE--EEEKEEEEKEEGRRRKKKKKRRRKEEEE---EK 112 EK+R+++R+KK EEE ++EEE+ EE+E+ ++E R+ +KK ++EEE+ E+ Sbjct: 978 PEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREE 1037 Query: 113 KKKRRRKTKKK 123 ++KRR + +++ Sbjct: 1038 REKRRLQERER 1048 Score = 84.0 bits (206), Expect = 3e-17 Identities = 44/135 (32%), Positives = 95/135 (70%), Gaps = 18/135 (13%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 ++K+ +K+ET +E E+ +EEE ++++E ++E+E+ +K + E R+E++EEE+ Sbjct: 242 EEKEWRKRETVLRKEEEKLQEEEP------QRQRELQEEEEQLRKLERQELRRERQEEEQ 295 Query: 61 KRKRKRK----KKKEEEEREEEEEEEEEEKEEEEKEEGRR----RKKKKKRR----RKEE 108 +++R R+ ++K+EEER E++EE E++E E++E RR R+++++RR R+E+ Sbjct: 296 QQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQ 355 Query: 109 EEEKKKKRRRKTKKK 123 EEE+++++ R+ +++ Sbjct: 356 EEERREQQLRREQEE 370 Score = 82.8 bits (203), Expect = 6e-17 Identities = 39/130 (30%), Positives = 96/130 (73%), Gaps = 10/130 (7%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGK--RKEKRKEKRKEKEKKKKTKETEKRKEKEEEE 59 +K+++K + EE + E +EEEE+ K R+E R+E+++E++++++ + ++ + K+EEE Sbjct: 254 RKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEE 313 Query: 60 KKRKRKRKKKKEEEEREEEEEEEEEE---KEEEEKEEGRRRKKKKKRR----RKEEEEEK 112 + R+++ ++++++E RE++EE E++ ++EE +E+ RR+++++RR R+E+EEE+ Sbjct: 314 R-REQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEER 372 Query: 113 KKKRRRKTKK 122 ++++ R+ ++ Sbjct: 373 REQQLRREQQ 382 Score = 81.6 bits (200), Expect = 1e-16 Identities = 40/131 (30%), Positives = 91/131 (69%), Gaps = 8/131 (6%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEG--KRKEKRKEKRKEKEKKKKTKETEKRKEKE-- 56 K++++K+ E E E+ + E+EE ++ KR+E+R+++R ++E++++ ++ KR+E E Sbjct: 551 KREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERL 610 Query: 57 EEEKKRKRKRKKKKEEEEREEE----EEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEK 112 E+E++R+++ K+++ EEER ++ EE+EE +++ +E+ RR+++ KR +EE E+ Sbjct: 611 EQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQ 670 Query: 113 KKKRRRKTKKK 123 + KR + +++ Sbjct: 671 RLKREHEEERR 681 Score = 81.3 bits (199), Expect = 2e-16 Identities = 41/130 (31%), Positives = 88/130 (67%), Gaps = 9/130 (6%) Query: 3 KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKR 62 +K++++E E+ EE ++EE++ R+E+ K +R+E E++ + K+ +++E++ ++R Sbjct: 979 EKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREER 1038 Query: 63 KRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEE---------EEKK 113 +++R +++E + REEEE ++EEE+ E+ E RRR++ +++ RKEEE E+ Sbjct: 1039 EKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEP 1098 Query: 114 KKRRRKTKKK 123 +KRRR+ +++ Sbjct: 1099 EKRRRQERER 1108 Score = 79.0 bits (193), Expect = 9e-16 Identities = 33/128 (25%), Positives = 87/128 (67%), Gaps = 5/128 (3%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 +++ +++++ ++ +EEE E K +++R+E+R ++E++++ ++ +E E E+ Sbjct: 410 EQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQ 469 Query: 61 KRKRKRKKKKEEEEREE-----EEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKK 115 +R++++ K+ +EEER E EEEE E++E E++ R +++++++R K +EEE++ + Sbjct: 470 ERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQ 529 Query: 116 RRRKTKKK 123 +R +++++ Sbjct: 530 QRLRSEQQ 537 Score = 78.2 bits (191), Expect = 1e-15 Identities = 35/115 (30%), Positives = 82/115 (71%) Query: 3 KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKR 62 +K++++E E EE ++EE++ R+E+ K +R+E E++ + +E +++E++ ++ Sbjct: 1099 EKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEP 1158 Query: 63 KRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRR 117 +++R+++ E + REEEE ++EEE+ E++E RR++++++ R +EE + +K+K+R Sbjct: 1159 EKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQR 1213 Score = 77.8 bits (190), Expect = 2e-15 Identities = 38/132 (28%), Positives = 88/132 (66%), Gaps = 10/132 (7%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 +++ ++++E E EE ++EE++ R+E K +R+E+E++ + +E +++E++ + Sbjct: 1067 ERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLRE 1126 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEE----------E 110 +R+++R+++ E + REEEE ++EEE+ E+ E RRR++ +++ R+EEE E Sbjct: 1127 EREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLRE 1186 Query: 111 EKKKKRRRKTKK 122 E++K+R+ + ++ Sbjct: 1187 EQEKRRQERERQ 1198 Score = 77.4 bits (189), Expect = 3e-15 Identities = 36/126 (28%), Positives = 86/126 (68%), Gaps = 5/126 (3%) Query: 3 KKKKKKETEETEETEETEEEEEKEGKRKEK--RKEKRKEKEKKKKTKETEKRKEKEEEEK 60 ++++++E E + E EEE ++ R+E+ R+E++ +E++ + ++ +R+++ E+ Sbjct: 352 RREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQ 411 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRR---RKEEEEEKKKKRR 117 + +R+++ ++E++ R E+EEE E+K E+E+ E R ++++++RR ++EEE E+ ++ R Sbjct: 412 QLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQER 471 Query: 118 RKTKKK 123 RK + K Sbjct: 472 RKQQLK 477 Score = 77.0 bits (188), Expect = 3e-15 Identities = 34/127 (26%), Positives = 85/127 (66%), Gaps = 4/127 (3%) Query: 1 KKKKKKKKETEETEE----TEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKE 56 +++++ K+E EE + EETE E++ K++ KR ++ + +E+ K +E E+R+++E Sbjct: 442 RREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQE 501 Query: 57 EEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKR 116 E++ +R++++++E+ + +EEEE +++ E++ R +++++++ K EEE++ ++ Sbjct: 502 RREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQE 561 Query: 117 RRKTKKK 123 RR+ + K Sbjct: 562 RREQRLK 568 Score = 77.0 bits (188), Expect = 3e-15 Identities = 40/124 (32%), Positives = 80/124 (64%), Gaps = 9/124 (7%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 +K+++ +E EE + EE E+ +E +R+ + +E+ +++E++ +E EKR+ +E E + Sbjct: 900 RKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQ 959 Query: 61 KRKRKRKKKKEEE---------EREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEE 111 RK K+ ++KEE+ R+E E++ EE+E +++EE R++++KRRR+E E + Sbjct: 960 YRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQ 1019 Query: 112 KKKK 115 +KK Sbjct: 1020 YRKK 1023 Score = 76.6 bits (187), Expect = 4e-15 Identities = 32/118 (27%), Positives = 86/118 (72%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 ++ +K++++ E + EE E ++E+E +E+R+++R+++ +++ +E E ++E+E+ + Sbjct: 1096 EEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLR 1155 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRR 118 + KR++++ E + EEEE ++EE++ +E+ +RR++++++ R+EEE +++K+++R Sbjct: 1156 EEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQR 1213 Score = 76.3 bits (186), Expect = 6e-15 Identities = 44/143 (30%), Positives = 87/143 (60%), Gaps = 22/143 (15%) Query: 1 KKKKKKKKETEETEET----EETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKE 56 K+++ ++ E EE E EE EEE ++ + E+++E+R+++ ++++ + E+R ++E Sbjct: 603 KREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKRE 662 Query: 57 EEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEE-------------EKEEGRRRKKKKKR 103 EEE++ +++ K++ EEE RE+E EEE+E+ E E E R+ K R Sbjct: 663 EEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSR 722 Query: 104 RRKEE-----EEEKKKKRRRKTK 121 RK+E +E+++K+RRR+++ Sbjct: 723 PRKQEGQRRRQEQEEKRRRRESE 745 Score = 76.3 bits (186), Expect = 6e-15 Identities = 40/144 (27%), Positives = 96/144 (66%), Gaps = 24/144 (16%) Query: 1 KKKKKKKKET--------EETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKR 52 ++++K+++ T E+ + ++ +EEE+E +R+E+ K +R+E+E++ + E++ Sbjct: 879 EEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYR---EEEQ 935 Query: 53 KEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEE---EKEEGRRRKKKKKRRRKEEE 109 ++EEE+ R+ + K++++E ER+ ++++ ++KEE+ E+ E RRR++++K+ R+EEE Sbjct: 936 LQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEE 995 Query: 110 ----------EEKKKKRRRKTKKK 123 EE++K+RR++ +++ Sbjct: 996 LQQEEEQLLREEREKRRRQEWERQ 1019 Score = 76.3 bits (186), Expect = 6e-15 Identities = 34/126 (26%), Positives = 93/126 (73%), Gaps = 4/126 (3%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 ++++K++++ +E + EE + ++E+E +E+R EKR+ +E++++ ++ +K ++KEE+ Sbjct: 916 EEREKRRRQEQERQYREEEQLQQEEEQLLREER-EKRRRQERERQYRKDKKLQQKEEQLL 974 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEE---EEKEEGRRRKKKKKRRRKEEEEEKKKKRR 117 + ++++++E E++ EEEE ++E+E+ EE+E+ RR++ +++ R+K+E ++++++ Sbjct: 975 GEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLL 1034 Query: 118 RKTKKK 123 R+ ++K Sbjct: 1035 REEREK 1040 Score = 75.9 bits (185), Expect = 7e-15 Identities = 31/127 (24%), Positives = 85/127 (66%), Gaps = 4/127 (3%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEE--- 57 +++ ++K E E E+ + E+EE ++ ++E+ E+ +++ +K++ K ++ + +E Sbjct: 431 EERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLK 490 Query: 58 -EEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKR 116 EE++R+ ++++++++ RE+EE E+ K +EE+E ++R + +++ R+E+EE +++ Sbjct: 491 LEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLL 550 Query: 117 RRKTKKK 123 +R+ +K+ Sbjct: 551 KREEEKR 557 Score = 75.9 bits (185), Expect = 7e-15 Identities = 42/136 (30%), Positives = 86/136 (63%), Gaps = 18/136 (13%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 +K++ +++E + EE E +EEE+ G+ +E R+ + E++ +K E+ ++EEE+ Sbjct: 1039 EKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRK-----EEELQQEEEQL 1093 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEE---EKEEGRRRKKKKKRRRKEEE-------- 109 R+ K++++E ER+ EEEE +++EE+ E+ E RRR++ +++ R+EEE Sbjct: 1094 LREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQL 1153 Query: 110 --EEKKKKRRRKTKKK 123 EE +K+RR++ +++ Sbjct: 1154 LREEPEKRRRQELERQ 1169 Score = 75.5 bits (184), Expect = 1e-14 Identities = 36/133 (27%), Positives = 91/133 (68%), Gaps = 10/133 (7%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 +++K++++E E ++ ++EE++ R+E+ K + +E+E++ + +E +++E++ + Sbjct: 1007 EREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGE 1066 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEE----------E 110 +R+ +R+++ E + R+EEE ++EEE+ E+ E RRR++++++ R+EEE E Sbjct: 1067 ERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLRE 1126 Query: 111 EKKKKRRRKTKKK 123 E++K+RR++ +++ Sbjct: 1127 EREKRRRQELERQ 1139 Score = 75.1 bits (183), Expect = 1e-14 Identities = 39/126 (30%), Positives = 86/126 (68%), Gaps = 3/126 (2%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKE--KEKKKKTKETEKRKEKEEE 58 +++++ ++E ++ + ETEE ++E R+ + E R++ +EK+++ +E + R +EEE Sbjct: 183 REERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEE 242 Query: 59 EKK-RKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRR 117 EK+ RKR+ +KEEE+ +EEE + + E +EEE++ + +++ +R R+EEE+++++ RR Sbjct: 243 EKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRR 302 Query: 118 RKTKKK 123 + ++ Sbjct: 303 EQQLRR 308 Score = 75.1 bits (183), Expect = 1e-14 Identities = 35/128 (27%), Positives = 89/128 (69%), Gaps = 5/128 (3%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEE--E 58 +++K++ K +E E E + EE+E + +++R+E++ +E++++ ++ KR+E+EE + Sbjct: 470 ERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQ 529 Query: 59 EKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRR---RKEEEEEKKKK 115 ++ R ++ ++++EE RE+ + EEE++ E+E+ E R ++++++RR K EEE ++++ Sbjct: 530 QRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQR 589 Query: 116 RRRKTKKK 123 +R+ +++ Sbjct: 590 LKREQEER 597 Score = 75.1 bits (183), Expect = 1e-14 Identities = 44/158 (27%), Positives = 84/158 (53%), Gaps = 42/158 (26%) Query: 1 KKKKKKKKETEET-------EETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRK 53 +++++ K+E EE EE E E+EE +E + K + E+ + ++ K ++ E+R+ Sbjct: 585 RRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQ 644 Query: 54 EKEEEEKKRKRKRKKKKEEEE--------REEEEEEEEEEKEEEEKEEGRRR-------- 97 ++ E++ +R+++ K+EEEE RE EEE E+E EEE+E+ R R Sbjct: 645 QQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKW 704 Query: 98 -------------------KKKKKRRRKEEEEEKKKKR 116 +K++ +RR++E+EEK+++R Sbjct: 705 QWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRR 742 Score = 74.3 bits (181), Expect = 2e-14 Identities = 41/131 (31%), Positives = 86/131 (65%), Gaps = 13/131 (9%) Query: 6 KKKETEETEETEETEEEEEKEGKRK--EKRKEKRKEK---------EKKKKTKETEKRKE 54 K ETEE + E+ E E +RK E+++++R+E+ EK+ + +ET RKE Sbjct: 197 KGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKE 256 Query: 55 KE--EEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEK 112 +E +EE+ ++++ +++EE+ R+ E +E E++EEE+++ R R++++ RR++EEE + Sbjct: 257 EEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERRE 316 Query: 113 KKKRRRKTKKK 123 +++ RR+ +++ Sbjct: 317 QQEERREQQER 327 Score = 73.6 bits (179), Expect = 4e-14 Identities = 28/123 (22%), Positives = 87/123 (70%), Gaps = 2/123 (1%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 ++++++ ++ E E E +EEE+++ + + +++ +RK++E++++ +E + +++ E++ Sbjct: 272 QEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQ 331 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120 + +R+++ ++E+EER E++ E+ EEE +E+ RR+++++RR ++ E++ +R ++ Sbjct: 332 EERREQQLRREQEERREQQLRREQ--EEERREQQLRREQEEERREQQLRREQQLRREQQL 389 Query: 121 KKK 123 +++ Sbjct: 390 RRE 392 Score = 73.2 bits (178), Expect = 5e-14 Identities = 28/126 (22%), Positives = 87/126 (69%), Gaps = 4/126 (3%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61 +K ++++ E +E E+ ++ +E + + K++E+R+E++++++ ++ + +++E E++ Sbjct: 279 RKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQ 338 Query: 62 RKRKRKKKKEEEEREEEEEEEEEE----KEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRR 117 +R++++++E++ R E+EEE E+ ++EEE+ E + R++++ RR ++ E++ +R Sbjct: 339 LRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRRE 398 Query: 118 RKTKKK 123 ++ +++ Sbjct: 399 QQLRRE 404 Score = 72.8 bits (177), Expect = 6e-14 Identities = 31/120 (25%), Positives = 78/120 (65%) Query: 3 KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKR 62 +++++ E+ E+ E++E + ++K +++R+E+ K++ +E ++EEE ++ Sbjct: 408 RREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERH 467 Query: 63 KRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKK 122 +++R+K++ + ++EEE E + EEEE+ E + R++++ RR +EE E++ KR+ + ++ Sbjct: 468 EQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEER 527 Score = 72.4 bits (176), Expect = 8e-14 Identities = 27/122 (22%), Positives = 87/122 (71%), Gaps = 1/122 (0%) Query: 3 KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKR 62 +++++ ++ EE E +EE ++ +R+E+++E+R+++ ++++ + E++ +E+EE++R Sbjct: 301 RREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERR 360 Query: 63 KRKRKKKKEEEEREEE-EEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTK 121 +++ ++++EEE RE++ E++ +E++ + E + R++++ RR ++ E++ +R ++ + Sbjct: 361 EQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 420 Query: 122 KK 123 ++ Sbjct: 421 RE 422 Score = 72.4 bits (176), Expect = 8e-14 Identities = 34/127 (26%), Positives = 85/127 (66%), Gaps = 4/127 (3%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKT---KETEKRKEKEE 57 ++++ ++++ E E+ + +EEEE+ +R ++ R+E+E++++ +E EKR E+E Sbjct: 503 REQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQER 562 Query: 58 EEKKRKRKRKKKKEE-EEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKR 116 E++ KR++++++++ +REEE ++ ++E+EE+ E R ++++ +R +EE E++ KR Sbjct: 563 REQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKR 622 Query: 117 RRKTKKK 123 +++ Sbjct: 623 EEPEEER 629 Score = 72.4 bits (176), Expect = 8e-14 Identities = 35/128 (27%), Positives = 86/128 (67%), Gaps = 6/128 (4%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTK-ETEKRKEKEEEEK 60 +++ ++++ E E+ + EEE+ E +R+E+R ++ +E+ + + K E E+R+++ + E+ Sbjct: 535 EQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQ 594 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRR-----KKKKKRRRKEEEEEKKKK 115 + + +++ K+EE ER E+EE E+ + EE EE RR+ +++++RR+++ E++++ Sbjct: 595 EERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQER 654 Query: 116 RRRKTKKK 123 R ++ K++ Sbjct: 655 REQRLKRE 662 Score = 72.0 bits (175), Expect = 1e-13 Identities = 30/129 (23%), Positives = 92/129 (71%), Gaps = 6/129 (4%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEK-EKKKKTKETEKRKEKE--E 57 ++++ +++ EE ++ + E++ K++E+R+E+++E+ E++++ ++ E+R+E++ Sbjct: 282 ERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRR 341 Query: 58 EEKKRKRKRKKKKEEEEREEEE---EEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKK 114 E+++R+ ++ ++++EEER E++ E+EEE +E++ + E + R++++ RR ++ E++ Sbjct: 342 EQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQL 401 Query: 115 KRRRKTKKK 123 +R ++ +++ Sbjct: 402 RREQQLRRE 410 Score = 71.2 bits (173), Expect = 2e-13 Identities = 39/139 (28%), Positives = 83/139 (59%), Gaps = 16/139 (11%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKE------KRKEKEKKKKTKETEKRKE 54 +++++ K+E EE + EEE ++ + K +++E KR+E E+ ++ + E+R + Sbjct: 562 RREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLK 621 Query: 55 KEEEEKKRKRKRKKKKEEEER----------EEEEEEEEEEKEEEEKEEGRRRKKKKKRR 104 +EE E++R+++ K +E+EER E E+ + E+EEE E+ +R+ +++RR Sbjct: 622 REEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERR 681 Query: 105 RKEEEEEKKKKRRRKTKKK 123 +E EE++++ R + K + Sbjct: 682 EQELAEEEQEQARERIKSR 700 Score = 71.2 bits (173), Expect = 2e-13 Identities = 34/129 (26%), Positives = 86/129 (66%), Gaps = 6/129 (4%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEE-- 58 +++++K++ E + + ++ ++KE + + EKR+ +E++KK +E E+ +++EE+ Sbjct: 945 REEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLL 1004 Query: 59 -EKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEE---EEEKKK 114 E++ KR+R++ + + +++E ++EEE+ EE+E+ R ++++++ R +EE EEE+ Sbjct: 1005 REEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLL 1064 Query: 115 KRRRKTKKK 123 R+T+++ Sbjct: 1065 GEERETRRR 1073 Score = 71.2 bits (173), Expect = 2e-13 Identities = 31/132 (23%), Positives = 85/132 (64%), Gaps = 9/132 (6%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 +++++++++ E EE ++ EE+ +E + K +R+E ++ ++++ ++ E++ +EE EK Sbjct: 1101 RRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEK 1160 Query: 61 KRKRKRKKKKEEEEREEEEEEE---------EEEKEEEEKEEGRRRKKKKKRRRKEEEEE 111 +R+++ +++ EEE ++EEE+ +E+E + +EE +++K+K+R ++E++ Sbjct: 1161 RRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQR 1220 Query: 112 KKKKRRRKTKKK 123 K + + +K+ Sbjct: 1221 SDLKWQWEPEKE 1232 Score = 70.9 bits (172), Expect = 2e-13 Identities = 31/123 (25%), Positives = 82/123 (66%), Gaps = 1/123 (0%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 +++++ ++E EE E + + +EE+E ++ R E++ +E++++ ++ KR+E++ E+ Sbjct: 502 RREQQLRREQEERRE-QRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQ 560 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120 +R+ +R K+++EE R++ + EEE +++ K E R +++ +R + E E++++R ++ Sbjct: 561 ERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRL 620 Query: 121 KKK 123 K++ Sbjct: 621 KRE 623 Score = 70.5 bits (171), Expect = 3e-13 Identities = 30/121 (24%), Positives = 78/121 (64%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 +++++++ + E+ E E+ + EE E +E+R+E+R ++E+ ++ + + K +E+EE+ Sbjct: 583 EERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEER 642 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120 ++++ R++++E E+ + EEEEE E+ K E +++++ +E+E+ +++ + R Sbjct: 643 RQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIP 702 Query: 121 K 121 K Sbjct: 703 K 703 Score = 70.5 bits (171), Expect = 3e-13 Identities = 35/119 (29%), Positives = 79/119 (66%), Gaps = 6/119 (5%) Query: 7 KKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTK-----ETEKRKEKEEEEKK 61 ++E E+ E + E+E ++E+ + R+E+EK+++ + E+ ++EEE+ Sbjct: 1095 REEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLL 1154 Query: 62 RKRKRKKKKEEEEREEEEEEE-EEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRK 119 R+ K++++E ER+ EEEE ++E+E+ +EE +R+++++R+ +EEEE +++KR+++ Sbjct: 1155 REEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQR 1213 Score = 69.7 bits (169), Expect = 5e-13 Identities = 29/130 (22%), Positives = 90/130 (69%), Gaps = 8/130 (6%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61 +++++++E ++ E + ++E +R+E+++E+R+++E++++ +E +++ + E+E++ Sbjct: 287 RRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEER 346 Query: 62 RKRKRKKKKEEEERE-----EEEEEEEEE---KEEEEKEEGRRRKKKKKRRRKEEEEEKK 113 R+++ ++++EEE RE E+EEE E+ +E++ + E + R++++ RR ++ E++ Sbjct: 347 REQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 406 Query: 114 KKRRRKTKKK 123 +R ++ +++ Sbjct: 407 LRREQQLRRE 416 Score = 69.7 bits (169), Expect = 5e-13 Identities = 34/134 (25%), Positives = 87/134 (64%), Gaps = 15/134 (11%) Query: 1 KKKKKKKKETEET--------EETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKR 52 ++K++ K++ EE EE E E++E +E + + +++E+R+++ K+++ +E ++ Sbjct: 471 RRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQ 530 Query: 53 KEKEEEEKKRKRKRKK----KKEEEEREEEEEEEEEEKEEEEKEEG---RRRKKKKKRRR 105 + + E++ +R+++ ++ K+EEE+R E+E E+ K E+E+ +R ++++++R Sbjct: 531 RLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRL 590 Query: 106 KEEEEEKKKKRRRK 119 K E+EE+ ++R ++ Sbjct: 591 KREQEERLEQRLKR 604 Score = 69.7 bits (169), Expect = 5e-13 Identities = 44/149 (29%), Positives = 90/149 (60%), Gaps = 26/149 (17%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTK--------ETEKR 52 +++++ ++ EE + +E +E + +R++++ + E+E+K++ + + R Sbjct: 841 QRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLR 900 Query: 53 KEK-----EEEEKKRKRKRKKKKEEEER---EEEEEEEEEEKEEEEKEEGRRR------- 97 KE+ EEEE +R+ + K++++E+ER EEE+ ++EEE+ E+ E RRR Sbjct: 901 KEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQY 960 Query: 98 KKKKKRRRKEEE---EEKKKKRRRKTKKK 123 +K KK ++KEE+ EE +K+RR++ +KK Sbjct: 961 RKDKKLQQKEEQLLGEEPEKRRRQEREKK 989 Score = 69.7 bits (169), Expect = 5e-13 Identities = 36/139 (25%), Positives = 87/139 (62%), Gaps = 16/139 (11%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEK-----RKEKEKKKKTKETEKR--- 52 +++++ ++ E E+ E EE+KE KR++++ ++ R+E+E+K++ +ET+++ Sbjct: 1281 QERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFRE 1340 Query: 53 -----KEKEEEEKKRKRKRKKKKEEEEREEEEEE---EEEEKEEEEKEEGRRRKKKKKRR 104 +E+EE+ +R+ + +K +EEE R +E+ EEE++ ++ E + K++++ R Sbjct: 1341 EEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLR 1400 Query: 105 RKEEEEEKKKKRRRKTKKK 123 +E E++ ++ R RK +++ Sbjct: 1401 CQEREQQLRQDRDRKFREE 1419 Score = 69.3 bits (168), Expect = 7e-13 Identities = 33/132 (25%), Positives = 93/132 (70%), Gaps = 9/132 (6%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRK-EKRKEKRKEKEKKKKTKETEKRKEKEEE- 58 ++++++++ E+ E E+ EE E++ +R+ E+R+E++ +E++++ +E + R+E+EEE Sbjct: 313 ERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEER 372 Query: 59 -EKKRKRKRKKKKEEEEREEEEEEEEEE--KEEEEKEEGRRRKKKKKRR----RKEEEEE 111 E++ +R+++ ++E++ R E++ E++ +E++ + E + R++++ RR R+E+EEE Sbjct: 373 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEE 432 Query: 112 KKKKRRRKTKKK 123 + +++ + +++ Sbjct: 433 RHEQKHEQERRE 444 Score = 69.3 bits (168), Expect = 7e-13 Identities = 45/159 (28%), Positives = 87/159 (54%), Gaps = 37/159 (23%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEK-----------RKEKEKKKKTKETE 50 +++ K++ EE E E EEE+E+ +R + R K R+ K + K+ Sbjct: 669 EQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEG 728 Query: 51 KRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKE--------EEEKEEGRR------ 96 +R+ +E+EEK+R+R+ + + +EEER +++EEE++ EE+ E GR+ Sbjct: 729 QRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARP 788 Query: 97 --RKKKKKRRRKEE----------EEEKKKKRRRKTKKK 123 R++++++ R EE EEE+K++RRR+ +++ Sbjct: 789 PLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRRER 827 Score = 68.2 bits (165), Expect = 2e-12 Identities = 26/123 (21%), Positives = 79/123 (64%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 +++ +++++ ++ ++ ++ R+E++ + +E+E+ ++ E E+R+++ + E+ Sbjct: 392 EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQ 451 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120 + +R K++EE ER E+E +++ K ++E+E R K ++ R+E++E ++++ RR+ Sbjct: 452 EERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQ 511 Query: 121 KKK 123 +++ Sbjct: 512 EER 514 Score = 67.8 bits (164), Expect = 2e-12 Identities = 35/140 (25%), Positives = 87/140 (62%), Gaps = 17/140 (12%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 +++++ K++ EE + E++ +++E+R++ K +E+K+ +E +++ K E+E+ Sbjct: 514 RREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEE 573 Query: 61 KR---------KRKRKKKKEEEEREEE--EEEEEEEKEEEEKEEGRRRKKKKKRRRK--- 106 +R +R+++ K+E+EER E+ + EE E E+EE+ E R ++++ + R+ Sbjct: 574 RRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQL 633 Query: 107 ---EEEEEKKKKRRRKTKKK 123 EE+EE+++++ R+ +++ Sbjct: 634 LKSEEQEERRQQQLRREQQE 653 Score = 67.4 bits (163), Expect = 3e-12 Identities = 35/143 (24%), Positives = 94/143 (65%), Gaps = 20/143 (13%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKE--KEKKKKTKETEKRKEKE-- 56 +K++++++ E +E + EEEE+ + + + ++ ++ ++ +E +++ + E+R++++ Sbjct: 816 EKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWR 875 Query: 57 ---EEEKKRKR----------KRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKR 103 EEE+KR+R ++ +K+++ +EEEEE + EE+E+ ++E R+ +++++ Sbjct: 876 WQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQ 935 Query: 104 RRKEEEE---EKKKKRRRKTKKK 123 ++EEE+ E+++KRRR+ +++ Sbjct: 936 LQQEEEQLLREEREKRRRQERER 958 Score = 65.5 bits (158), Expect = 1e-11 Identities = 36/124 (29%), Positives = 76/124 (61%), Gaps = 7/124 (5%) Query: 5 KKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRK- 63 ++++E + E + + EEE +R++KR+E+ +E + ++ E ++R E+ + +++ + Sbjct: 113 RRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEE 172 Query: 64 --RKRKKKKEEEEREEEEEE----EEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRR 117 R+R++ +E EER EEE+ + E EE EE RR++ + RRK EE+++++R Sbjct: 173 LWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRE 232 Query: 118 RKTK 121 R+ + Sbjct: 233 RQDR 236 Score = 65.5 bits (158), Expect = 1e-11 Identities = 24/123 (19%), Positives = 82/123 (66%), Gaps = 2/123 (1%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61 +++++ + ++ ++ E++ +++ +R+++ + +++ ++ +E E+ ++K E+E++ Sbjct: 384 RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERR 443 Query: 62 RKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRR--KEEEEEKKKKRRRK 119 +R +++++E + + EEE E ++E K++ +R +++++R R K EEEE+++++ R+ Sbjct: 444 EQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERR 503 Query: 120 TKK 122 ++ Sbjct: 504 EQQ 506 Score = 64.7 bits (156), Expect = 2e-11 Identities = 28/124 (22%), Positives = 78/124 (62%), Gaps = 3/124 (2%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 + ++++++ ++ + EE+ E+E +++ KR++++ ++EK+ +E E+++ ++E ++ Sbjct: 1277 RDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDR 1336 Query: 61 KRKRKRKKKKEEEE---REEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRR 117 K + + + +E EE R +E + + E+E +E+GR+ ++++R R++E E K K Sbjct: 1337 KFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEE 1396 Query: 118 RKTK 121 ++ + Sbjct: 1397 QQLR 1400 Score = 64.7 bits (156), Expect = 2e-11 Identities = 32/135 (23%), Positives = 81/135 (60%), Gaps = 12/135 (8%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 ++++ + + E E+ +E E++ R+++R K +E+E++ + +E E++ +EE++ Sbjct: 1657 REQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQL 1716 Query: 61 KRKRKRKKKKEEEEREEEEEEE------------EEEKEEEEKEEGRRRKKKKKRRRKEE 108 +R+ +K +EEE+ +E E+E EEE+ E+EE + R++++ R+ +EE Sbjct: 1717 RRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREE 1776 Query: 109 EEEKKKKRRRKTKKK 123 E+ ++++ ++ + + Sbjct: 1777 EQLRQEREEQQLRSQ 1791 Score = 64.7 bits (156), Expect = 2e-11 Identities = 43/163 (26%), Positives = 95/163 (58%), Gaps = 40/163 (24%) Query: 1 KKKKKKKKETEETEETEETEEEE-----------EKEGKRKEKRKEKRKEKEKKKKTKET 49 ++++ ++K EE + +ETE+E+ E+E R E+ +++ + +E+ +K +E Sbjct: 1717 RRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREE 1776 Query: 50 EKRKEKEEEEKKRKRK--RKKKKEEEEREEEEEE-------------EEEEKEEEEKEEG 94 E+ +++ EE++ R ++ RK ++EE+ R+E EE+ EEE+ + EE+E+ Sbjct: 1777 EQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQR 1836 Query: 95 RRRKK------------KKKRRRKEEE--EEKKKKRRRKTKKK 123 R+++ ++K RR+E+E +E+++KRR++ ++K Sbjct: 1837 LRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERK 1879 Score = 63.9 bits (154), Expect = 3e-11 Identities = 39/156 (25%), Positives = 85/156 (54%), Gaps = 36/156 (23%) Query: 3 KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK-- 60 +++++K E+ E E EE+ EK+ +R E+R +R+++E ++ +E ++R+E+ EE+ Sbjct: 135 QRRRQKRQEQERELAEGEEQSEKQ-ERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQL 193 Query: 61 -------------------------KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGR 95 +RK + +K+++ ER++ +EEEEKE ++E Sbjct: 194 QSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVL 253 Query: 96 RRKKKK--------KRRRKEEEEEKKKKRRRKTKKK 123 R++++K +R +EEEE+ +K R++ +++ Sbjct: 254 RKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRE 289 Score = 63.5 bits (153), Expect = 4e-11 Identities = 37/127 (29%), Positives = 84/127 (66%), Gaps = 12/127 (9%) Query: 1 KKKKKKKKETEET-EETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEE 59 +++K++++ET+ E E+ +E E++ R+++R K +E+E + + + RK EEE+ Sbjct: 1325 REEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRH---QEQGRKFLEEEQ 1381 Query: 60 KKRKRKRKKK--KEE-----EEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEK 112 + R+++R++K KEE +ERE++ ++ + K EE+++ R+++ +K R+EE++ + Sbjct: 1382 RLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRK-FREEEQQVR 1440 Query: 113 KKKRRRK 119 +++R RK Sbjct: 1441 RQERERK 1447 Score = 63.2 bits (152), Expect = 5e-11 Identities = 38/139 (27%), Positives = 88/139 (63%), Gaps = 19/139 (13%) Query: 1 KKKKKKKKETEETEETEET-----EEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRK-- 53 ++++ +++ EE + + T EE+ E+ +R R R+++E++ + +E ++R+ Sbjct: 750 EEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQR 809 Query: 54 ---EKEEEEKKRKRKRKKKKEEEEREEEEE----EEEEEKEEEEK--EEGRRRKKKKKRR 104 E+EE+E++R+++R+++KE + EEEE+ E ++ +EEE +E + R++ +++R Sbjct: 810 FLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQR 869 Query: 105 RKEE---EEEKKKKRRRKT 120 R ++ + E+++KRRR T Sbjct: 870 RDQKWRWQLEEERKRRRHT 888 Score = 62.8 bits (151), Expect = 6e-11 Identities = 33/137 (24%), Positives = 80/137 (58%), Gaps = 17/137 (12%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 +++++++ EE ++ E+ EE+E KE+R+ +R+E+EK+ + E E++ ++ E + Sbjct: 791 REQRERQLRAEERQQREQRFLPEEEE---KEQRRRQRREREKELQFLEEEEQLQRRERAQ 847 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRK--------------KKKKRRRK 106 + + + +E++ER +E+ ++K + EE R+R+ +K+++ + Sbjct: 848 QLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQ 907 Query: 107 EEEEEKKKKRRRKTKKK 123 EEEEE +++ R K +++ Sbjct: 908 EEEEELQREEREKRRRQ 924 Score = 62.0 bits (149), Expect = 1e-10 Identities = 32/124 (25%), Positives = 77/124 (62%), Gaps = 7/124 (5%) Query: 1 KKKKKKKKETEETEETEETEEEE---EKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEE 57 +++++++K +E ++ E E E+E R+E +E+ + +E+ +K E E+ + + E Sbjct: 1701 RRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPERE 1760 Query: 58 EEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRR 117 E++ R+++R +K EEE+ +E EE++ + +E R+ +++++ R+E EE++ + ++ Sbjct: 1761 EQQLRRQERDRKFREEEQLRQEREEQQLRSQESD----RKFREEEQLRQEREEQQLRPQQ 1816 Query: 118 RKTK 121 R K Sbjct: 1817 RDGK 1820 Score = 61.6 bits (148), Expect = 1e-10 Identities = 32/114 (28%), Positives = 68/114 (59%), Gaps = 1/114 (0%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 +++K++++E E EE ++EE++ R+E K +R+E E++ + +E E ++E+E+ + Sbjct: 1127 EREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEE-ELQQEEEQLLR 1185 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKK 114 + + KR++++E + REEEE + ++ K+ E+ R K + KE K Sbjct: 1186 EEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNK 1239 Score = 61.6 bits (148), Expect = 1e-10 Identities = 31/133 (23%), Positives = 78/133 (58%), Gaps = 12/133 (9%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 +++ ++++ + E E+ +E+E K ++ ++ R+++ ++K +E + R+E E+E+ Sbjct: 1681 EQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQL 1740 Query: 61 KRKRKRKKKKEEEEREEEEEEE------------EEEKEEEEKEEGRRRKKKKKRRRKEE 108 +R+ + +K EEE+ E EE+ EEE+ +E+EE + R ++ R+ +EE Sbjct: 1741 RRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREE 1800 Query: 109 EEEKKKKRRRKTK 121 E+ ++++ ++ + Sbjct: 1801 EQLRQEREEQQLR 1813 Score = 61.6 bits (148), Expect = 1e-10 Identities = 32/132 (24%), Positives = 82/132 (62%), Gaps = 9/132 (6%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 +++ + ++E ++ E + E+E R+E+ +++ + +E +K +E E+ +++ EE++ Sbjct: 1752 EEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQ 1811 Query: 61 KRKRKR--KKKKEEEEREEEEEEEE--EEKEEEEKEEGRRRKKKKKRRRK-----EEEEE 111 R ++R K + EEE+ + EE+E+ +E++ + + E + ++K RR + EEE++ Sbjct: 1812 LRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQK 1871 Query: 112 KKKKRRRKTKKK 123 ++++R RK +++ Sbjct: 1872 RRQERERKLREE 1883 Score = 61.2 bits (147), Expect = 2e-10 Identities = 33/127 (25%), Positives = 76/127 (59%), Gaps = 7/127 (5%) Query: 3 KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKR 62 + +K++ +E EE E E + +E+ + R+++E++++ T + + +E+ E+ R Sbjct: 722 RPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGR 781 Query: 63 KRKRKKKKEEEEREE----EEEEEEEEK---EEEEKEEGRRRKKKKKRRRKEEEEEKKKK 115 +R + E+RE EE ++ E++ EEEEKE+ RR+++++++ + EEE++ + Sbjct: 782 QRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQ 841 Query: 116 RRRKTKK 122 RR + ++ Sbjct: 842 RRERAQQ 848 Score = 61.2 bits (147), Expect = 2e-10 Identities = 32/129 (24%), Positives = 80/129 (62%), Gaps = 7/129 (5%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEK-----EKKKKTKETEKRKEK 55 + +K +++E E+ + EEE++ +++ +RK ++E+ E++++ ++ RK + Sbjct: 1358 RDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFR 1417 Query: 56 EEEEK--KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKK 113 EEE++ +++R RK ++EE++ +E E + +EE++ + R RK +++ + +E EE++ Sbjct: 1418 EEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQ 1477 Query: 114 KKRRRKTKK 122 R+ + +K Sbjct: 1478 LHRQERDRK 1486 Score = 60.8 bits (146), Expect = 2e-10 Identities = 26/122 (21%), Positives = 79/122 (64%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 ++ +++++E + +E ++ +E ++ R+++ ++ R+E+++ + + K +E+E++ + Sbjct: 1381 QRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVR 1440 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120 +++R+RK +EE++ +E + E+E+ +E ++ +++R RK EEE++ +R+ + Sbjct: 1441 RQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERD 1500 Query: 121 KK 122 +K Sbjct: 1501 RK 1502 Score = 60.8 bits (146), Expect = 2e-10 Identities = 24/117 (20%), Positives = 78/117 (66%) Query: 3 KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKR 62 +++++++ ++E++ EEE+ + +E+++ + ++++ K + +E + + E++E+ ++ Sbjct: 1780 RQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQ 1839 Query: 63 KRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRK 119 +R R+ + EE+ +E+ EE++ +E+E+ RR+++++K R + ++K+++R + Sbjct: 1840 ERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHR 1896 Score = 60.5 bits (145), Expect = 3e-10 Identities = 23/130 (17%), Positives = 84/130 (64%), Gaps = 7/130 (5%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEK-------RKEKRKEKEKKKKTKETEKRK 53 +++++++ E+ EE E + E++ +R+++ R+E++ +E++ + ++ +R+ Sbjct: 357 EERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 416 Query: 54 EKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKK 113 ++ E++ +R++++++ E++ E+E E+ ++E+EE+ + +R+++ +R +E +++ Sbjct: 417 QQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQL 476 Query: 114 KKRRRKTKKK 123 K+ + + +++ Sbjct: 477 KRDQEEERRE 486 Score = 60.5 bits (145), Expect = 3e-10 Identities = 41/179 (22%), Positives = 88/179 (49%), Gaps = 56/179 (31%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 +K+++++ E + EE E +EEE+ + +EKR+++R+ + ++++ + +KRK++ +E Sbjct: 1159 EKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDED 1218 Query: 61 KRK-------------------------------------RKRKKKK-------EEEERE 76 +R R R+ ++ E++ER+ Sbjct: 1219 QRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERD 1278 Query: 77 EEEE------------EEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123 E+E EEE+ + EE+KE RR +K ++ ++ EE ++K+RR++T +K Sbjct: 1279 REQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRK 1337 Score = 60.5 bits (145), Expect = 3e-10 Identities = 28/119 (23%), Positives = 72/119 (60%), Gaps = 2/119 (1%) Query: 6 KKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRK 65 +++E + +E ++ + + ++ +E++KE +++ + + EK+ +EE E+KR+R+ Sbjct: 1273 EQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQ 1332 Query: 66 R--KKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKK 122 +K +EEE+ +E EE+ ++E +++ + +++ RK EEE++ +R+ + +K Sbjct: 1333 ETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERK 1391 Score = 60.5 bits (145), Expect = 3e-10 Identities = 28/133 (21%), Positives = 84/133 (63%), Gaps = 10/133 (7%) Query: 1 KKKKKKKKETEETEETEETEEE-----EEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEK 55 +++++ +K EE ++ E E EE++ +R+E ++ R+E++ +++T++ + R+++ Sbjct: 1685 RRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQE 1744 Query: 56 E-----EEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEE 110 EEE+ R + +++ +ER+ + EEE+ ++E E+++ R ++ +K R +E+ Sbjct: 1745 RYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLR 1804 Query: 111 EKKKKRRRKTKKK 123 +++++++ + +++ Sbjct: 1805 QEREEQQLRPQQR 1817 Score = 60.1 bits (144), Expect = 4e-10 Identities = 28/118 (23%), Positives = 74/118 (62%), Gaps = 5/118 (4%) Query: 6 KKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRK 65 +++E + EE +E+ +E+++ +R+E+E+K +E + R ++ E++ ++ R Sbjct: 1354 RRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRD 1413 Query: 66 RKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123 RK ++EE++ +E + + +EE++ R+++++R+ EEE++ +++R RK +++ Sbjct: 1414 RKFREEEQQLSRQERDRKFREEEQQV-----RRQERERKFLEEEQQLRQERHRKFREE 1466 Score = 60.1 bits (144), Expect = 4e-10 Identities = 26/126 (20%), Positives = 84/126 (66%), Gaps = 7/126 (5%) Query: 1 KKKKKKKKETEETEETEETEEE-----EEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEK 55 + ++ ++K EE ++ + + EE++ +R+E+ +++R+++++K + +E +++ + Sbjct: 1509 RSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQERE 1568 Query: 56 EEEEKKRKRKRKKKKEEEE--REEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKK 113 E++ +++R RK + EE++ R+E+E + E++++ ++EG+++ ++++ R+ E+E+ Sbjct: 1569 EQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLL 1628 Query: 114 KKRRRK 119 ++R + Sbjct: 1629 QEREEQ 1634 Score = 60.1 bits (144), Expect = 4e-10 Identities = 38/144 (26%), Positives = 83/144 (57%), Gaps = 22/144 (15%) Query: 1 KKKKKKKKETEETEETEETEEEE----EKEGK-RKEKRKEKRKEKEKKKKTKETEKRKEK 55 +++ + +K EE + +E EE++ E++ K R E++K +R+E+E+K E + R+++ Sbjct: 1549 RRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQE 1608 Query: 56 EEEEKKRKRKRKKKKEEEEREEEEE-------------EEEEEKEEEEKEEGRRRKKKKK 102 +++ +++R RK +++E+ +E EE EEE + +E+E+ R + +K Sbjct: 1609 GQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRK 1668 Query: 103 RRRKE----EEEEKKKKRRRKTKK 122 R +E E EE++ +R+ + +K Sbjct: 1669 FREEEQLLQEGEEQQLRRQERDRK 1692 Score = 60.1 bits (144), Expect = 4e-10 Identities = 35/131 (26%), Positives = 81/131 (61%), Gaps = 14/131 (10%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61 +K + +++ +E E E+E++ +R+E +++ R+E+++K + E + +E+EE++ Sbjct: 1579 RKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDE-QLLQEREEQQLH 1637 Query: 62 RKRKRKKKKEEE---EREEEEEE----------EEEEKEEEEKEEGRRRKKKKKRRRKEE 108 R+ + +K EEE R+E E++ EEE+ +E +E+ RR+++ ++ R+EE Sbjct: 1638 RQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEE 1697 Query: 109 EEEKKKKRRRK 119 ++ ++++R RK Sbjct: 1698 QQLRRQERERK 1708 Score = 60.1 bits (144), Expect = 4e-10 Identities = 24/122 (19%), Positives = 78/122 (63%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 +++ ++++E ++ E + E+E R+E+ +++ + +++ K + E++ + EE+E+ Sbjct: 1776 EEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQ 1835 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120 + +++R ++ EE+ +E+ E++E +EE ++R+++++R+ +EE +++K ++ Sbjct: 1836 RLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRH 1895 Query: 121 KK 122 ++ Sbjct: 1896 RQ 1897 Score = 59.7 bits (143), Expect = 5e-10 Identities = 31/116 (26%), Positives = 74/116 (63%), Gaps = 4/116 (3%) Query: 6 KKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRK 65 +++E + ++ + EEE++ R+E R K +E+E++ + +E E++ +EE++ +++R Sbjct: 1402 QEREQQLRQDRDRKFREEEQQLSRQE-RDRKFREEEQQVRRQERERKFLEEEQQLRQERH 1460 Query: 66 RKKKKEEEEREEEEEEEEEEKEEEEK---EEGRRRKKKKKRRRKEEEEEKKKKRRR 118 RK ++EE+ +E EE++ +E + K EE + R++++ R+ +E+E ++ R+ Sbjct: 1461 RKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERK 1516 Score = 59.7 bits (143), Expect = 5e-10 Identities = 28/126 (22%), Positives = 79/126 (62%), Gaps = 4/126 (3%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61 +++++ ++ + EE + +E EE++ R+E+ ++ R E++K ++ ++ K E E++ ++ Sbjct: 1547 QQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRR 1606 Query: 62 RKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKK----KKKRRRKEEEEEKKKKRR 117 ++ +++ ++E + + E+E+ +E+EE++ R +K + + RR+E E++ + R Sbjct: 1607 QEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRD 1666 Query: 118 RKTKKK 123 RK +++ Sbjct: 1667 RKFREE 1672 Score = 59.7 bits (143), Expect = 5e-10 Identities = 35/135 (25%), Positives = 76/135 (56%), Gaps = 15/135 (11%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRK---EKEKKKKTKETEKRKEKEEE 58 ++++ +K EE + E E++ R K +E+ + E E+++ ++ RK +EEE Sbjct: 1638 RQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEE 1697 Query: 59 EKKRKRKRKKKKEEEE------------REEEEEEEEEEKEEEEKEEGRRRKKKKKRRRK 106 ++ R+++R++K +EE REEE+ +E E+E+ ++E R+ ++++ R Sbjct: 1698 QQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRP 1757 Query: 107 EEEEEKKKKRRRKTK 121 E EE++ +++ R K Sbjct: 1758 EREEQQLRRQERDRK 1772 Score = 59.7 bits (143), Expect = 5e-10 Identities = 29/124 (23%), Positives = 81/124 (65%), Gaps = 6/124 (4%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKE---- 56 +K +++++ +E EE + +E +++ + +E+ +++R+E++ + + ++ + R E+E Sbjct: 1771 RKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQL 1830 Query: 57 EEEKKRKRKRKKK--KEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKK 114 EE+++R R+ + + + EE+ +E+ EE+E ++EE +RR++++++ R+E ++K Sbjct: 1831 EEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQK 1890 Query: 115 KRRR 118 + +R Sbjct: 1891 EEQR 1894 Score = 59.3 bits (142), Expect = 7e-10 Identities = 36/136 (26%), Positives = 84/136 (61%), Gaps = 14/136 (10%) Query: 2 KKKKKKKETEETEETEETEEE----EEKEGKRKEKRKEKR------KEKEKKKKTKETEK 51 ++++ +K EE ++ E E EE++ R+E+ ++ R +E+E+++ ++ Sbjct: 1425 RQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERD 1484 Query: 52 RKEKEEEEKKRKRKRKKK-KEEEEREEEEEEEEEEKEEEEKEEGRRRK---KKKKRRRKE 107 RK EEE++ R+++R +K +E+E R +E E + E+E++ + R+RK ++++ RR+E Sbjct: 1485 RKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQE 1544 Query: 108 EEEEKKKKRRRKTKKK 123 +++++ R RK +++ Sbjct: 1545 RGQQRRQDRDRKFREE 1560 Score = 59.3 bits (142), Expect = 7e-10 Identities = 27/124 (21%), Positives = 81/124 (65%), Gaps = 4/124 (3%) Query: 4 KKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRK 63 ++++ + + +E + E+E+ + +E+++ R+E+++K +E + R+++ E++ + Sbjct: 1605 RRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHD 1664 Query: 64 RKRKKKKEEEEREEEEEEE----EEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRK 119 R RK ++EE+ +E EE++ E +++ E+E+ RR++++++ +EE++ ++++ RK Sbjct: 1665 RDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERK 1724 Query: 120 TKKK 123 +++ Sbjct: 1725 FREE 1728 Score = 59.3 bits (142), Expect = 7e-10 Identities = 27/120 (22%), Positives = 80/120 (66%), Gaps = 2/120 (1%) Query: 4 KKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRK 63 ++++++ +E + EEE + +R+E+ ++ R ++++K + +E ++ +E++ ++++ Sbjct: 1629 QEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQE 1688 Query: 64 RKRKKKKEEEE--REEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTK 121 R RK ++EE++ R+E E + +E+++ ++E R+ +++++ R+E E+E+ +++ R K Sbjct: 1689 RDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRK 1748 Score = 58.9 bits (141), Expect = 9e-10 Identities = 26/127 (20%), Positives = 80/127 (62%), Gaps = 7/127 (5%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 + ++ +++ + + + +E E EG+ + +++E+ ++++++++ +E +++++ +E + Sbjct: 125 RDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQERE 184 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEE----KEEGRRRKKKKKRRRKE---EEEEKK 113 +R+ + ++ + + E EE +EE+ E + +GR K++++R R++ +EEE+K Sbjct: 185 ERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEK 244 Query: 114 KKRRRKT 120 + R+R+T Sbjct: 245 EWRKRET 251 Score = 58.5 bits (140), Expect = 1e-09 Identities = 30/124 (24%), Positives = 72/124 (58%), Gaps = 6/124 (4%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 + +K++ + + +E + E E + + +E+ +++E+E+++ + +EK E + Sbjct: 722 RPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGR 781 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKE----EEEKEEGRRRKKKKKRRRKE--EEEEKKK 114 +R R +E+ ER+ EE ++ ++ EEE++E RRR+++++ + + EEEE+ + Sbjct: 782 QRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQ 841 Query: 115 KRRR 118 +R R Sbjct: 842 RRER 845 Score = 58.5 bits (140), Expect = 1e-09 Identities = 33/128 (25%), Positives = 76/128 (59%), Gaps = 6/128 (4%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKE---- 56 +K+ K++ + E+ EE EEK +++ RK + +E+ +++ ++ +R+E++ Sbjct: 1304 QKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFR 1363 Query: 57 EEEKKRKRKRKKKKEEEEREEEEEEEEE--EKEEEEKEEGRRRKKKKKRRRKEEEEEKKK 114 EEE + + + +K EEE+R +E E + ++E++ + + R ++ ++ R RK EEE++ Sbjct: 1364 EEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQL 1423 Query: 115 KRRRKTKK 122 R+ + +K Sbjct: 1424 SRQERDRK 1431 Score = 58.5 bits (140), Expect = 1e-09 Identities = 30/128 (23%), Positives = 80/128 (62%), Gaps = 5/128 (3%) Query: 1 KKKKKKKKETEETEETEETEEE-EEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEE 59 ++++ +++E E EE + +E+E + ++ R K +E+E++ +E +++ +EE++ Sbjct: 1379 EEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQ 1438 Query: 60 KKRKRKRKKKKEEEEREEEEE----EEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKK 115 +R+ + +K EEE++ +E EEE+ +E +E+ R+++ ++ +EE++ ++++ Sbjct: 1439 VRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQE 1498 Query: 116 RRRKTKKK 123 R RK +++ Sbjct: 1499 RDRKFREQ 1506 Score = 57.8 bits (138), Expect = 2e-09 Identities = 25/118 (21%), Positives = 76/118 (64%), Gaps = 3/118 (2%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 ++++ +++E + +E +E + +E+++ R+++++K +E + R+++ +++ Sbjct: 1490 EEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQR 1549 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEK---EEGRRRKKKKKRRRKEEEEEKKKK 115 ++ R RK ++EE+ R+E EE++ +E + K EE + R+++++R+ E+E++ +++ Sbjct: 1550 RQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQ 1607 Score = 57.8 bits (138), Expect = 2e-09 Identities = 27/120 (22%), Positives = 76/120 (63%), Gaps = 1/120 (0%) Query: 4 KKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRK 63 +++++E + + + EEE+ + E+++ +R+E+++K + +E + R+++ E + ++ Sbjct: 1653 RRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQE 1712 Query: 64 RKRKKKKEEEEREEEEEEEEEEKEEEE-KEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKK 122 ++ +++E E + EEE+ +E E+E+ + + R RK ++ + + E EE++ +R+ + +K Sbjct: 1713 EQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRK 1772 Score = 57.8 bits (138), Expect = 2e-09 Identities = 29/121 (23%), Positives = 74/121 (61%), Gaps = 6/121 (4%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEE--- 57 +++ + ++ + E E+ +E E++ R ++R K + +E++ + +E E+R +E Sbjct: 1785 EQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQ 1844 Query: 58 ---EEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKK 114 EE+ +++ +++E+E +EEE++ +E+E + +EE RR++K+++R ++ E K + Sbjct: 1845 YRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQ 1904 Query: 115 K 115 + Sbjct: 1905 E 1905 Score = 57.4 bits (137), Expect = 3e-09 Identities = 26/127 (20%), Positives = 79/127 (62%), Gaps = 4/127 (3%) Query: 1 KKKKKKKKETEETEETEETEEEE----EKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKE 56 +++++ +K EE + +E EE++ E + K +E+ + +++ +E++ + ++ + + E Sbjct: 1765 RRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWE 1824 Query: 57 EEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKR 116 EE+ + + + ++ ++E +R+ EE+ +E+ +EE ++++++RR+E E + +++ Sbjct: 1825 EEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEH 1884 Query: 117 RRKTKKK 123 R+ +K+ Sbjct: 1885 IRRQQKE 1891 Score = 56.2 bits (134), Expect = 6e-09 Identities = 28/123 (22%), Positives = 76/123 (61%), Gaps = 6/123 (4%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61 ++++++K +E E+ +E+ +R++ R K +E+E+ ++ +E ++ +E + K Sbjct: 1526 RQQRQRKFLQE----EQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKF 1581 Query: 62 RKRKRKKKKEEEEREEEEEEEEEEKEEEEKE--EGRRRKKKKKRRRKEEEEEKKKKRRRK 119 R ++K +++E+ER+ E+E++ ++E +++ + R RK ++ + +E EE++ R+ + Sbjct: 1582 RLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQER 1641 Query: 120 TKK 122 +K Sbjct: 1642 DRK 1644 Score = 55.8 bits (133), Expect = 8e-09 Identities = 34/149 (22%), Positives = 78/149 (52%), Gaps = 34/149 (22%) Query: 5 KKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKR 64 K +++ E ++ E++E +E + K + +E+R E+ K++ +E + +E EEE+++ R Sbjct: 635 KSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQAR 694 Query: 65 KRKK-------------------------KKEEEEREEEEEEEEEEKEE-----EEKEEG 94 +R K +K+E +R +E+EE+ + E +E+E Sbjct: 695 ERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERA 754 Query: 95 RRRKKKKKRRR----KEEEEEKKKKRRRK 119 R+++++++RR + + EEK ++ R++ Sbjct: 755 HRQQQEEEQRRDFTWQWQAEEKSERGRQR 783 Score = 55.8 bits (133), Expect = 8e-09 Identities = 24/121 (19%), Positives = 79/121 (65%), Gaps = 2/121 (1%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEE--E 58 + +K +++E + + + + + EE++ R+++R+ K E+E++ + + K +E+E+ + Sbjct: 1412 RDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQ 1471 Query: 59 EKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRR 118 E++ ++ +++++ + EEE++ +E++ + +E+ R ++ +++ +EE++ +++R+R Sbjct: 1472 EREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQR 1531 Query: 119 K 119 K Sbjct: 1532 K 1532 Score = 55.5 bits (132), Expect = 1e-08 Identities = 32/128 (25%), Positives = 80/128 (62%), Gaps = 9/128 (7%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETE-KRKEKE--- 56 ++K K+++ +E E+ ++ R+E+++ R+E+++K + +E + +R+E+E Sbjct: 1389 ERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKF 1448 Query: 57 -EEEKKRKRKRKKKKEEEEREEEEEEEE----EEKEEEEKEEGRRRKKKKKRRRKEEEEE 111 EEE++ +++R +K EEE+ +E EE+ +E++ + EE ++ +++++ R+ E+E Sbjct: 1449 LEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQEL 1508 Query: 112 KKKKRRRK 119 + ++ RK Sbjct: 1509 RSQEPERK 1516 Score = 55.5 bits (132), Expect = 1e-08 Identities = 30/138 (21%), Positives = 82/138 (59%), Gaps = 16/138 (11%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRK----EKRKEKEKKKKTKETEKRKEKE 56 +K ++++++ E + EEE++ +++ +RK E++ +E+ +K +E E+ ++ Sbjct: 1414 RKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQER 1473 Query: 57 EEEKKRKRKRKKKKEEEE------------REEEEEEEEEEKEEEEKEEGRRRKKKKKRR 104 EE++ +++R +K EEE RE+E +E E++ E+E+ R++++++ Sbjct: 1474 EEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKF 1533 Query: 105 RKEEEEEKKKKRRRKTKK 122 +EE++ ++++R ++ ++ Sbjct: 1534 LQEEQQLRRQERGQQRRQ 1551 Score = 55.5 bits (132), Expect = 1e-08 Identities = 26/126 (20%), Positives = 79/126 (62%), Gaps = 4/126 (3%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 ++++ +++ + E E+ +E E++ +++R K E+E++ + +E + RK +E+E + Sbjct: 1451 EEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERD-RKFREQELR 1509 Query: 61 KRKRKRKKKKEEEEREEEEEEE---EEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRR 117 ++ +RK +EE++ ++ + +EE++ +E G++R++ + R+ +EEE+ ++++ Sbjct: 1510 SQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREE 1569 Query: 118 RKTKKK 123 ++ ++ Sbjct: 1570 QQLSRQ 1575 Score = 55.5 bits (132), Expect = 1e-08 Identities = 33/138 (23%), Positives = 83/138 (60%), Gaps = 15/138 (10%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 +++ +K E E +E E++ + RK + +E+ ++ ++++ + E+ ++ EEE+ Sbjct: 1639 QERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQ 1698 Query: 61 KRKRKRKKKK----EEEEREEEEE----EEEEEKEEEEKEEGRRRKKKKK-------RRR 105 + +R+ +++K E++ R +E E EEE+ ++E E+E+ RR+++ +K R Sbjct: 1699 QLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPE 1758 Query: 106 KEEEEEKKKKRRRKTKKK 123 +EE++ ++++R RK +++ Sbjct: 1759 REEQQLRRQERDRKFREE 1776 Score = 55.1 bits (131), Expect = 1e-08 Identities = 24/119 (20%), Positives = 72/119 (60%), Gaps = 2/119 (1%) Query: 6 KKKETEETEETEETE--EEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRK 63 K +E E+ + E+++ + + ++ + +++ +++E++++ + R EEE+ +R+ Sbjct: 1243 KGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLERE 1302 Query: 64 RKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKK 122 +++ K+ + + +EE++ EE+EE+ + + RK +++ + +E EE+ +R+ + +K Sbjct: 1303 EQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRK 1361 Score = 55.1 bits (131), Expect = 1e-08 Identities = 28/128 (21%), Positives = 79/128 (61%), Gaps = 6/128 (4%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKK-----KKTKETEKRKEK 55 +++ ++ ++ + EE ++ +E R+E+++ +R+E+E+K ++ ++ RK + Sbjct: 1405 EQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFR 1464 Query: 56 EEEEKKRKRKRKK-KKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKK 114 EEE+ ++R+ ++ ++E +R+ EEE++ ++E +++ + + ++ RK EEE++ Sbjct: 1465 EEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQL 1524 Query: 115 KRRRKTKK 122 R+++ +K Sbjct: 1525 HRQQRQRK 1532 Score = 55.1 bits (131), Expect = 1e-08 Identities = 33/144 (22%), Positives = 87/144 (60%), Gaps = 25/144 (17%) Query: 2 KKKKKKKETEETEETEETEE-------------EEEKEGKRKEKRKEKRKEKEKKKKTKE 48 ++++ +K EE + +E EE EEE++ +R+E+ RK +E++ +++E Sbjct: 1456 RQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQER---DRKFREQELRSQE 1512 Query: 49 TEKRKEKEEEEKKRKRKRKKKKEEEE---REEEEEEEEEEKEEEEKEEGRRRKKKKKRRR 105 E++ +EE++ R+++++K +EE+ R+E ++ ++++ + +EE + R+++++++ Sbjct: 1513 PERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQL 1572 Query: 106 KEEEEEKK------KKRRRKTKKK 123 +E ++K K RR++ ++K Sbjct: 1573 SRQERDRKFRLEEQKVRRQEQERK 1596 Score = 55.1 bits (131), Expect = 1e-08 Identities = 23/125 (18%), Positives = 81/125 (64%), Gaps = 3/125 (2%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 + +K +++E E + EEE++ +++ +RK ++E++ +++ + ++R++++ + + Sbjct: 1499 RDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFR 1558 Query: 61 KRKRKRKKKKEEEEREEEEEEE---EEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRR 117 + ++ R++++E++ +E + + EE+K +++E + + +++ RR+E +++ +++R Sbjct: 1559 EEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERD 1618 Query: 118 RKTKK 122 RK ++ Sbjct: 1619 RKFRE 1623 Score = 54.7 bits (130), Expect = 2e-08 Identities = 29/140 (20%), Positives = 85/140 (60%), Gaps = 18/140 (12%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKE-------KEKKKKTKETEKRKE 54 +++++++E + E + +EE+ R+++ +E+R++ +EK ++ ++ + Sbjct: 729 QRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARP 788 Query: 55 KEEEEKKRKRKRKKKKEEEEREEEEEEEEE-------EKEEE----EKEEGRRRKKKKKR 103 E+++R+ + +++++ E+R EEEE+E E+E+E E+EE +R+++ ++ Sbjct: 789 PLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQ 848 Query: 104 RRKEEEEEKKKKRRRKTKKK 123 ++EE+ ++ + RR+++++ Sbjct: 849 LQEEEDGLQEDQERRRSQEQ 868 Score = 54.3 bits (129), Expect = 2e-08 Identities = 31/150 (20%), Positives = 78/150 (52%), Gaps = 38/150 (25%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKE----KE 56 ++++ K++E EE + + EE++E ++++ R+E+++ +E++ K +E E+R E +E Sbjct: 616 REQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKRE 675 Query: 57 EEEKKRKRKRKKKKEEEEREE----------------------------------EEEEE 82 EE++R+++ ++++E+ RE +E+ Sbjct: 676 HEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQ 735 Query: 83 EEEKEEEEKEEGRRRKKKKKRRRKEEEEEK 112 EE++ E E + +++ R+++EEE+ + Sbjct: 736 EEKRRRRESELQWQEEERAHRQQQEEEQRR 765 Score = 53.9 bits (128), Expect = 3e-08 Identities = 29/97 (29%), Positives = 62/97 (63%), Gaps = 5/97 (5%) Query: 20 EEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEE 79 +EE+ KE + R+++E +++ E R + EEE ++R++K++ E+ERE E Sbjct: 96 DEEKRARCDGKESLLQDRRQEEDQRRF---EPRDRQLEEEPGQRRRQKRQ--EQERELAE 150 Query: 80 EEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKR 116 EE+ EK+E ++ R+R+ ++ R+++E +E++++R Sbjct: 151 GEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERR 187 Score = 53.1 bits (126), Expect = 5e-08 Identities = 19/119 (15%), Positives = 74/119 (62%) Query: 3 KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKR 62 K ++ ++ + E+++ + + +++ + +++R ++++++ ++ ++ +EE+ ++ Sbjct: 1243 KGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLERE 1302 Query: 63 KRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTK 121 ++K K+++ + +EE++ EE +E+ ++E R+ +++++ +E EE+ +++ R K Sbjct: 1303 EQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRK 1361 Score = 52.8 bits (125), Expect = 7e-08 Identities = 27/128 (21%), Positives = 74/128 (57%), Gaps = 5/128 (3%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKE---KEKKKKTKETEKRKEKEE 57 +++++++K +E ++ E E++ R K +E+ ++ +E+ +K +E E++ ++E Sbjct: 1384 RRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQE 1443 Query: 58 EEKKRKRKRKKKKEEEEREEEEEEE--EEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKK 115 E+K + ++ ++E R+ EEE+ +E +E++ + R RK ++ ++ +E +K Sbjct: 1444 RERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKF 1503 Query: 116 RRRKTKKK 123 R ++ + + Sbjct: 1504 REQELRSQ 1511 Score = 52.4 bits (124), Expect = 9e-08 Identities = 33/128 (25%), Positives = 74/128 (57%), Gaps = 12/128 (9%) Query: 1 KKKKKKKKETEETEETEETEEEEEK-EGKRKEKRKEKRKEKEKKKKTK-------ETEKR 52 +++ K+++E E E+ + E EEE+ E + E+ +E+ +E+ K + K E + R Sbjct: 656 EQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADAR 715 Query: 53 KEKE-EEEKKRKRKRKKKKEEEEREEEEEE---EEEEKEEEEKEEGRRRKKKKKRRRKEE 108 + K +K++ +R+++++EE+R E E +EEE+ +++E +R+ + + EE Sbjct: 716 QSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEE 775 Query: 109 EEEKKKKR 116 + E+ ++R Sbjct: 776 KSERGRQR 783 Score = 52.4 bits (124), Expect = 9e-08 Identities = 31/137 (22%), Positives = 76/137 (55%), Gaps = 23/137 (16%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEK--------------------RKEK 40 +K+++++ E + EE E +EEE+ + EKR+ + R+E+ Sbjct: 1129 EKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQ 1188 Query: 41 EKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKK 100 EK+++ +E R+ +EEEE +R++++++ ++E++R + + + E EKE ++ K + Sbjct: 1189 EKRRQERE---RQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGR 1245 Query: 101 KKRRRKEEEEEKKKKRR 117 + + ++ E+ + + R+ Sbjct: 1246 ENEQFRQLEDSQLRDRQ 1262 Score = 52.0 bits (123), Expect = 1e-07 Identities = 23/119 (19%), Positives = 75/119 (63%), Gaps = 3/119 (2%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 +++ +K E E+ +E + + ++ R ++ + K E+E++ ++ +++ +EE++ Sbjct: 1481 QERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQL 1540 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRK 119 +R+ + ++++++ +R+ EEE+ ++ EE++ R+++ ++ R EE++ +++++ RK Sbjct: 1541 RRQERGQQRRQDRDRKFREEEQLRQEREEQQ---LSRQERDRKFRLEEQKVRRQEQERK 1596 Score = 52.0 bits (123), Expect = 1e-07 Identities = 23/124 (18%), Positives = 75/124 (60%), Gaps = 5/124 (4%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 ++++ +++E + + + E+E R+E+ +++ +E+ +K + E++ ++E+E+ Sbjct: 1536 EEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQER 1595 Query: 61 K-----RKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKK 115 K ++ +R++ +++ +E + + E+E+ +E+EE + ++++ R+ EEE + +++ Sbjct: 1596 KFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQ 1655 Query: 116 RRRK 119 R + Sbjct: 1656 EREQ 1659 Score = 50.8 bits (120), Expect = 3e-07 Identities = 22/84 (26%), Positives = 57/84 (67%), Gaps = 3/84 (3%) Query: 15 ETEETEEEEEKEGKRKEKRKEKRKEKE---KKKKTKETEKRKEKEEEEKKRKRKRKKKKE 71 E E+ + EE+++ R+E+ ++ R E++ ++K +E ++ ++EE++++++R+RK ++E Sbjct: 1824 EEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREE 1883 Query: 72 EEEREEEEEEEEEEKEEEEKEEGR 95 R+++EE+ + E + +EG+ Sbjct: 1884 HIRRQQKEEQRHRQVGEIKSQEGK 1907 >gi|239747174 PREDICTED: hypothetical protein XP_002343931, partial [Homo sapiens] Length = 213 Score = 84.3 bits (207), Expect = 2e-17 Identities = 41/128 (32%), Positives = 81/128 (63%), Gaps = 5/128 (3%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTK-ETEKRKEKEEE- 58 ++ + +++E + E E E E +++E +E+ KE+E + T+ + E++K+KE E Sbjct: 57 ERDRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREM 116 Query: 59 EKKRKRKRKKKKE---EEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKK 115 E+ R R+R+K+KE E + + E + E E + E E+E GR RK + + R +E E +++++ Sbjct: 117 ERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERE 176 Query: 116 RRRKTKKK 123 R+R+TK++ Sbjct: 177 RKRETKER 184 Score = 74.7 bits (182), Expect = 2e-14 Identities = 32/129 (24%), Positives = 80/129 (62%), Gaps = 6/129 (4%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 +++++++++ + ETE ++E + + E +E++K+KE++ + +R++++E + Sbjct: 73 ERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGR 132 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEK------KK 114 +R+ R+ +E E + E E E E++ E++ R R++K++R RK E +E+ ++ Sbjct: 133 ERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDMER 192 Query: 115 KRRRKTKKK 123 +R+R+T +K Sbjct: 193 ERQRETDRK 201 Score = 71.6 bits (174), Expect = 1e-13 Identities = 33/125 (26%), Positives = 81/125 (64%), Gaps = 4/125 (3%) Query: 1 KKKKKKKKETEETEETE-ETEEEEEKEGKR-KEKRKEKRKEKEKKKKTKETEKRKEKEEE 58 ++++ K++ET+ ET+ E ++++E+E +R +++ +EK+KE ++++T R+ + + Sbjct: 89 ERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQA 148 Query: 59 EKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRR 118 E++R+ R++K E+ RE E E + E + + E +E R + R ++ E ++K+ R+R Sbjct: 149 ERERETGRERKTEDRHRERERERKRERERKRETKE--RERHTDMERERQRETDRKRDRQR 206 Query: 119 KTKKK 123 +++++ Sbjct: 207 ESERE 211 Score = 70.1 bits (170), Expect = 4e-13 Identities = 27/122 (22%), Positives = 75/122 (61%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61 ++++ ++E ++ ET+ E + + K+KE+ E+ +++E++K+ + +R+ E +++ Sbjct: 84 RQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRE 143 Query: 62 RKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTK 121 R+R+ ++++E + E+ E + E ++E R+R+ K++ R + E E++++ RK Sbjct: 144 RERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDMERERQRETDRKRD 203 Query: 122 KK 123 ++ Sbjct: 204 RQ 205 Score = 66.6 bits (161), Expect = 4e-12 Identities = 30/109 (27%), Positives = 68/109 (62%), Gaps = 2/109 (1%) Query: 3 KKKKKKETEETEETEETEEEEEKE-GKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61 ++++K++ E E + E E++KE G+ ++ +E +E+E++ + +E E +E++ E++ Sbjct: 106 RERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAE-RERETGRERKTEDRH 164 Query: 62 RKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEE 110 R+R+R++K+E E + E +E E E E++ RK+ ++R + E + Sbjct: 165 RERERERKRERERKRETKERERHTDMERERQRETDRKRDRQRESERERD 213 Score = 66.2 bits (160), Expect = 6e-12 Identities = 27/121 (22%), Positives = 76/121 (62%), Gaps = 2/121 (1%) Query: 5 KKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKK-KTKETEKRKEKEEEEKKRK 63 ++++ ET+ + +E + E + E+ +++ +E+ +++ + +E EK+ ++E E ++ + Sbjct: 19 RQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRER 78 Query: 64 RKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKR-RRKEEEEEKKKKRRRKTKK 122 + + ++ E ERE ++E E + E ++E ++++++ +R R +E E++K+ R R+T + Sbjct: 79 ERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDR 138 Query: 123 K 123 + Sbjct: 139 E 139 Score = 65.5 bits (158), Expect = 1e-11 Identities = 28/106 (26%), Positives = 67/106 (63%), Gaps = 3/106 (2%) Query: 1 KKKKKKKKETEETEETEETEEEE---EKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEE 57 +++K+K++E E + E +++E E++ R+ R+ +R+ + +++ +E + E Sbjct: 107 ERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRE 166 Query: 58 EEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKR 103 E++RKR+R++K+E +ERE + E E + E +++ R+R+ +++R Sbjct: 167 RERERKRERERKRETKERERHTDMERERQRETDRKRDRQRESERER 212 Score = 64.7 bits (156), Expect = 2e-11 Identities = 34/128 (26%), Positives = 74/128 (57%), Gaps = 11/128 (8%) Query: 7 KKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEE---EKKRK 63 + +TE ETE + + +R+E +E+ + KE K + + +E+ ++++ E E+ R Sbjct: 2 ESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRD 61 Query: 64 RKRKKKKEEE-EREEEEEEEEEEKEEEEKEEGRRRK-------KKKKRRRKEEEEEKKKK 115 R+R+K+ + E ER+ E E + + + E E+E + R+ ++++++KE E E+ + Sbjct: 62 REREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRD 121 Query: 116 RRRKTKKK 123 R R+ +K+ Sbjct: 122 REREKQKE 129 Score = 64.7 bits (156), Expect = 2e-11 Identities = 27/130 (20%), Positives = 82/130 (63%), Gaps = 7/130 (5%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKR-KEKRKEKRKEKEKKKKT-KETEKRKEKEEE 58 +++++ +E + +E++ + E++ +R +E+ +E+ +++E++K+T +E E+++E+E + Sbjct: 22 ERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERERD 81 Query: 59 -----EKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKK 113 E +R+R ++++ + + E ++++E+E E + R K+K+ R ++ + E Sbjct: 82 RDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETD 141 Query: 114 KKRRRKTKKK 123 ++R R+ +++ Sbjct: 142 RERERQAERE 151 Score = 51.6 bits (122), Expect = 1e-07 Identities = 22/88 (25%), Positives = 56/88 (63%), Gaps = 2/88 (2%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 K+ ++++ ET+ E + E E+E R+ K +++ +E+E+++K +E E+++E +E E+ Sbjct: 128 KEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERK-RERERKRETKERER 186 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEE 88 +R++++E + R+ + + E E + + Sbjct: 187 HTDMERERQRETD-RKRDRQRESERERD 213 >gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] Length = 290 Score = 84.0 bits (206), Expect = 3e-17 Identities = 44/136 (32%), Positives = 87/136 (63%), Gaps = 16/136 (11%) Query: 2 KKKKKKKETE-------ETEETEETEEEEEKEGKRKEKRKEKRK---EKEKKKKTKETEK 51 ++K+++++TE ETE E + E EK+ +R+ +R R+ EKE++++T Sbjct: 149 REKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERD 208 Query: 52 RKEKEEEEKKRKRKRKKKKEEEEREEEEEE----EEEEKEEEEKEEGRRRKKKKKRRRKE 107 R+ K + E++R+ R+ ++E + R E + + +E ++E + KEE R+K++KK R+KE Sbjct: 209 RQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEE--RKKERKKERKKE 266 Query: 108 EEEEKKKKRRRKTKKK 123 +E+KK+++RR+ KK+ Sbjct: 267 RKEKKKEEKRREDKKR 282 Score = 82.0 bits (201), Expect = 1e-16 Identities = 32/115 (27%), Positives = 77/115 (66%), Gaps = 1/115 (0%) Query: 3 KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKR 62 ++++ +E E+ +E E + + + KE+ ++ +E+++++KT +TE+++E + E ++ Sbjct: 170 ERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKT-QTERQRETDREGERE 228 Query: 63 KRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRR 117 +R++++ + +R +E + E + KEE +KE + RKK++K ++KEE+ + KKR+ Sbjct: 229 TDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRK 283 Score = 79.3 bits (194), Expect = 7e-16 Identities = 28/122 (22%), Positives = 81/122 (66%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61 +++++ + E+TE+ + + + ++E +RKEK + +++EK+ + + +R++++ E++ Sbjct: 77 RQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERE 136 Query: 62 RKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTK 121 R R R+++++ + +E E + E++++ + + E R + +++ ++KE E E+ + R+R T+ Sbjct: 137 RDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTE 196 Query: 122 KK 123 K+ Sbjct: 197 KE 198 Score = 78.6 bits (192), Expect = 1e-15 Identities = 32/126 (25%), Positives = 83/126 (65%), Gaps = 4/126 (3%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKK---KTKETEKRKEKEE 57 + + ++K+ +TE+ + + E E E +R ++ +EK+KE+E ++ + ++TEK +E++ Sbjct: 145 RDRDREKERERQTEKDRDGQRETETERER-DREREKQKERETERDRDRQRDTEKERERQT 203 Query: 58 EEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRR 117 + ++ ++++ + + + E + E E E + + E +++ R +++ ++R RKEE ++++KK R Sbjct: 204 DRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKER 263 Query: 118 RKTKKK 123 +K +K+ Sbjct: 264 KKERKE 269 Score = 78.2 bits (191), Expect = 1e-15 Identities = 31/129 (24%), Positives = 82/129 (63%), Gaps = 6/129 (4%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 + + ++++ + E+ E + E++++G+R+ + + +R + +K+K +ETE+ ++++ + + Sbjct: 137 RDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTE 196 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKK------KKRRRKEEEEEKKK 114 K + ++ ++ + +R+ + E + E E E+E RRR+++ K+R R+ + +E++K Sbjct: 197 KERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERK 256 Query: 115 KRRRKTKKK 123 K R+K +KK Sbjct: 257 KERKKERKK 265 Score = 78.2 bits (191), Expect = 1e-15 Identities = 32/113 (28%), Positives = 74/113 (65%), Gaps = 2/113 (1%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 + ++++K++ ETE + + + EKE +R+ R+ R+ K + ++ +ET++ E+E + Sbjct: 173 RDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETD-- 230 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKK 113 +R+ +++ + +ER+ E + +EE K+E +KE + RK+KKK ++ E++++K Sbjct: 231 RRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRK 283 Score = 77.0 bits (188), Expect = 3e-15 Identities = 33/125 (26%), Positives = 79/125 (63%), Gaps = 3/125 (2%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61 + ++K+ E E E E+ + E + + +E+ +++ +EKE++++T++ + + E E++ Sbjct: 113 RDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERE 172 Query: 62 RKRKRKKKKEEEEREEEEEEEEEEKEEE---EKEEGRRRKKKKKRRRKEEEEEKKKKRRR 118 R R+R+K+KE E + + + + EKE E ++E R+RK + +R+R+ + E +++ RR Sbjct: 173 RDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRR 232 Query: 119 KTKKK 123 + +++ Sbjct: 233 RERQR 237 Score = 73.2 bits (178), Expect = 5e-14 Identities = 36/122 (29%), Positives = 78/122 (63%), Gaps = 5/122 (4%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKK-KTKETEKRKEKEEEE 59 K+ ++++++ +ET + E++ E E R E+ K+K +E+E+ + + +E ++ +EKE E Sbjct: 97 KRDRERRRKEKETNRNRDREKQTEIERDR-EREKQKGRERERDRGRERERDRDREKERER 155 Query: 60 KKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRK 119 + K + +++ E ERE + E E++++ E E++ R+R +K+R R+ + E + R+RK Sbjct: 156 QTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRE---RDRQRK 212 Query: 120 TK 121 T+ Sbjct: 213 TQ 214 Score = 62.8 bits (151), Expect = 6e-11 Identities = 28/101 (27%), Positives = 64/101 (63%), Gaps = 8/101 (7%) Query: 22 EEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEE 81 + K+ ++++E+ + +EK +K ++ ++++++E R+RK+K+ R+ E++ Sbjct: 67 QAHKDADGDDRQRERDRVREKTEKERDRDRKRDRE-------RRRKEKETNRNRDREKQT 119 Query: 82 EEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKK 122 E E E EK++GR R++ + R R E + +++K+R R+T+K Sbjct: 120 EIERDREREKQKGRERERDRGRER-ERDRDREKERERQTEK 159 Score = 59.3 bits (142), Expect = 7e-10 Identities = 24/106 (22%), Positives = 66/106 (62%), Gaps = 2/106 (1%) Query: 20 EEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK--RKRKRKKKKEEEEREE 77 + ++ +G +++ +++ +EK +K++ ++ ++ +E+ +EK+ R R R+K+ E E E Sbjct: 67 QAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDRE 126 Query: 78 EEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123 E+++ E+E + E R + ++K R ++ E+++ +R +T+++ Sbjct: 127 REKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERE 172 Score = 58.5 bits (140), Expect = 1e-09 Identities = 26/112 (23%), Positives = 71/112 (63%), Gaps = 18/112 (16%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKT-----KETEKRKEK 55 +++K+K++ETE + + E+E + +E+ ++++ + E++++T +ET++R+E+ Sbjct: 176 EREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRER 235 Query: 56 EEE-------------EKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEG 94 + + +++RK++RKK++++E +E+++EE+ E ++ + EG Sbjct: 236 QRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKWGEG 287 >gi|169167715 PREDICTED: hypothetical protein [Homo sapiens] Length = 285 Score = 80.5 bits (197), Expect = 3e-16 Identities = 39/131 (29%), Positives = 83/131 (63%), Gaps = 10/131 (7%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKE---KKKKTKETEKRKEKEEE 58 +K+++ + + ETE EE E + +++EK +E+++++E K + ETEK +++E E Sbjct: 106 RKRERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDRERE 165 Query: 59 ----EKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEE---EEE 111 E+ R R+R+++K+ E R + + E + EKE+ E++ R+++++K R R+ E + + Sbjct: 166 MGETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRD 225 Query: 112 KKKKRRRKTKK 122 K++ R R+ +K Sbjct: 226 KERDRERQREK 236 Score = 66.6 bits (161), Expect = 4e-12 Identities = 34/136 (25%), Positives = 82/136 (60%), Gaps = 14/136 (10%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKR-KEKEKKK-----KTKETEKRKE 54 +++++++K +E ++ E E++++ +RK R+ +R +++++K+ + +ETE ++ Sbjct: 64 RERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRETETERQ 123 Query: 55 KEEEEKKRKRKRKKKKEEE-------EREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKE 107 EE E++R RKR+K +E + +++ E E E++ E E E R + +++ R+K+ Sbjct: 124 -EERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERERQKQ 182 Query: 108 EEEEKKKKRRRKTKKK 123 E + + R R+ +K+ Sbjct: 183 RETRRDRDRERQREKE 198 Score = 64.3 bits (155), Expect = 2e-11 Identities = 32/124 (25%), Positives = 70/124 (56%), Gaps = 19/124 (15%) Query: 1 KKKKKKKKETEETEETE---------ETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEK 51 ++ +K++K+ E + E ETE++ ++E + E + + +E+E++K Sbjct: 129 QRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERERQK------- 181 Query: 52 RKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEE 111 + E + R R+R+++KE+ ER+ + ++E E+ E+E GR R K++ R R+ E++ Sbjct: 182 ---QRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQREKDR 238 Query: 112 KKKK 115 ++K Sbjct: 239 DRQK 242 Score = 63.5 bits (153), Expect = 4e-11 Identities = 33/146 (22%), Positives = 82/146 (56%), Gaps = 23/146 (15%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEK---KKKTKETEKRKEKEE 57 ++K+ K++ E+ E E+ + + K + +++ +++ +++E+ + + ETE+++E+E Sbjct: 69 QRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRETETERQEERER 128 Query: 58 E-----EKKRKRKRKK-------------KKEEEERE--EEEEEEEEEKEEEEKEEGRRR 97 + EK R+R+R++ K + ERE E E + E+E +++ E RR Sbjct: 129 QRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERERQKQRETRRD 188 Query: 98 KKKKKRRRKEEEEEKKKKRRRKTKKK 123 + ++++R KE+ E + +++ + K + Sbjct: 189 RDRERQREKEDRERDRDRQKEREKDR 214 Score = 62.4 bits (150), Expect = 8e-11 Identities = 35/124 (28%), Positives = 65/124 (52%), Gaps = 15/124 (12%) Query: 15 ETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKR---KKKKE 71 E E E E + + KE+ +EK +E EK + + R+ + ++ RKR+R + ++ Sbjct: 59 ERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRET 118 Query: 72 EEEREEEEEEEEEEKEEEEKEEGRRR------------KKKKKRRRKEEEEEKKKKRRRK 119 E ER+EE E + + K E+++E R+R +K + R R+ E E+ + R R+ Sbjct: 119 ETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERE 178 Query: 120 TKKK 123 +K+ Sbjct: 179 RQKQ 182 Score = 56.6 bits (135), Expect = 5e-09 Identities = 20/88 (22%), Positives = 59/88 (67%) Query: 32 KRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEK 91 + +E+++E+E+++K + R++ E EK R R+RK+ +E + + + + E + + + Sbjct: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRE 117 Query: 92 EEGRRRKKKKKRRRKEEEEEKKKKRRRK 119 E R+++++++R ++ E++++++R+R+ Sbjct: 118 TETERQEERERQRDRKREKDRERQRQRE 145 Score = 52.0 bits (123), Expect = 1e-07 Identities = 20/95 (21%), Positives = 58/95 (61%), Gaps = 1/95 (1%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 +K + +++E ETE + E E +K+ + + R ++ +++EK+ + ++ +++KE+E++ Sbjct: 157 EKDRDREREMGETERYRDRERERQKQRETRRDR-DRERQREKEDRERDRDRQKEREKDRY 215 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGR 95 + + + + +E +RE + E++ + ++ + GR Sbjct: 216 RERETGRDRDKERDRERQREKDRDRQKAIDCVPGR 250 >gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo sapiens] Length = 956 Score = 79.7 bits (195), Expect = 5e-16 Identities = 41/121 (33%), Positives = 82/121 (67%), Gaps = 2/121 (1%) Query: 3 KKKKKKETEETE-ETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61 KK K TE+ + + +E K+ K + +R+EK K KE+ K+ KE K+K++EE+E K Sbjct: 323 KKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELK 382 Query: 62 RKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTK 121 K +R++K+E++E+E+ E++ +E+ +E++E K ++KR+++EE+ +++++R K + Sbjct: 383 EK-ERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAE 441 Query: 122 K 122 K Sbjct: 442 K 442 Score = 76.6 bits (187), Expect = 4e-15 Identities = 36/108 (33%), Positives = 73/108 (67%) Query: 16 TEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEER 75 T++ + ++ K + +R ++R K+ K + + EK K KEE ++ ++ +KKK+EE+E Sbjct: 322 TKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKEL 381 Query: 76 EEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123 +E+E E+ EK+E+EK E +R K+++++ R+E E K +++R+K ++K Sbjct: 382 KEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEK 429 Score = 73.9 bits (180), Expect = 3e-14 Identities = 40/114 (35%), Positives = 72/114 (63%), Gaps = 2/114 (1%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61 +K K + + ++ ++ + E+E K K K + KR ++E KKK +E ++ KEKE EK Sbjct: 331 EKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREK- 389 Query: 62 RKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKK 115 + K +K+K E++R +EE +E ++ E K E +R+K+++KR R+EE+ K +K Sbjct: 390 -REKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEK 442 Score = 72.0 bits (175), Expect = 1e-13 Identities = 41/119 (34%), Positives = 75/119 (63%), Gaps = 10/119 (8%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61 K+ K + E EE E+ +E E KR ++ +K+KE+EK+ K KE R+EK E+++K Sbjct: 346 KQLKLRAEREEKEKLKE-------EAKRAKEEAKKKKEEEKELKEKE---RREKREKDEK 395 Query: 62 RKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120 K ++++ KEE +E +E E + +E+ +KEE +R ++++KR + E+ E + ++ KT Sbjct: 396 EKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAEITRFFQKPKT 454 Score = 69.3 bits (168), Expect = 7e-13 Identities = 35/90 (38%), Positives = 63/90 (70%), Gaps = 1/90 (1%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRK-EKEKKKKTKETEKRKEKEEEE 59 ++K+K K+E + +E + ++EEEKE K KE+R+++ K EKEK +K + E+R+++ +E Sbjct: 355 EEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQEA 414 Query: 60 KKRKRKRKKKKEEEEREEEEEEEEEEKEEE 89 + K + K+KKEEE+R EEE+ + ++ E Sbjct: 415 LEAKLEEKRKKEEEKRLREEEKRIKAEKAE 444 Score = 41.2 bits (95), Expect = 2e-04 Identities = 24/68 (35%), Positives = 39/68 (57%), Gaps = 5/68 (7%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 +K +K+K E + +E E +E E K +EKRK KE++K+ +E EKR + E+ E Sbjct: 391 EKDEKEKAEKQRLKEERRKERQEALEAKLEEKRK-----KEEEKRLREEEKRIKAEKAEI 445 Query: 61 KRKRKRKK 68 R ++ K Sbjct: 446 TRFFQKPK 453 Score = 30.0 bits (66), Expect = 0.46 Identities = 20/81 (24%), Positives = 37/81 (45%), Gaps = 11/81 (13%) Query: 48 ETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEE-----------EEEKEEEEKEEGRR 96 E + +E EEEE + ++++ E+E+E+ E+E EE + Sbjct: 597 EVDSDEEWEEEEPGESLSHSEGDDDDDMGEDEDEDDGFFVPHGYLSEDEGVTEECADPEN 656 Query: 97 RKKKKKRRRKEEEEEKKKKRR 117 K ++K + KE +E K +R Sbjct: 657 HKVRQKLKAKEWDEFLAKGKR 677 >gi|102467235 inner centromere protein antigens 135/155kDa isoform 1 [Homo sapiens] Length = 918 Score = 79.3 bits (194), Expect = 7e-16 Identities = 41/136 (30%), Positives = 86/136 (63%), Gaps = 13/136 (9%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEK---EE 57 KKK+ ++K + E+TE+ +EE E K K+K K+ E+ + ++ +E E R+ + +E Sbjct: 595 KKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQE 654 Query: 58 EEKKRKRKRKKKKEEEEREE----------EEEEEEEEKEEEEKEEGRRRKKKKKRRRKE 107 EE++R ++ +KK+EEE+E E+ E+E +E+E +E+ RR ++++++ R+E Sbjct: 655 EEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERRE 714 Query: 108 EEEEKKKKRRRKTKKK 123 +E + ++ RR+ +++ Sbjct: 715 QERQLAEQERRREQER 730 Score = 76.3 bits (186), Expect = 6e-15 Identities = 35/118 (29%), Positives = 74/118 (62%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61 KKK K+ EE E + EEE + +++ +E+R ++ +KK +E ++R K E K+ Sbjct: 624 KKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKR 683 Query: 62 RKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRK 119 +R++++ E+ER E+E E+E +E+E +E+ R+ ++++RR +E + +++ + R+ Sbjct: 684 LAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQERE 741 Score = 73.2 bits (178), Expect = 5e-14 Identities = 37/131 (28%), Positives = 79/131 (60%), Gaps = 8/131 (6%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRK--------EKRKEKRKEKEKKKKTKETEKR 52 K++++ +K + E E+ +EE++K+ ++K EK KE+R +EK KK +K Sbjct: 573 KREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKM 632 Query: 53 KEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEK 112 +E E K+ + R+ + ++E EE +E +K++EE++E R+ + KR ++ E+E+ Sbjct: 633 EEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQER 692 Query: 113 KKKRRRKTKKK 123 +++ RR+ +++ Sbjct: 693 REQERREQERR 703 Score = 72.0 bits (175), Expect = 1e-13 Identities = 31/123 (25%), Positives = 83/123 (67%), Gaps = 2/123 (1%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 KKK+++++ + E + E+ E+E + +E+R+++R+E+E++++ + ++R+ E+E + Sbjct: 666 KKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERR 725 Query: 61 KRKRKRKKKKEEEEREE--EEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRR 118 + + + + ++E +ERE+ ++E+ ++E EEK++ +++ +R+ +EE+E+K K+ Sbjct: 726 REQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAG 785 Query: 119 KTK 121 +K Sbjct: 786 ASK 788 Score = 71.6 bits (174), Expect = 1e-13 Identities = 30/118 (25%), Positives = 78/118 (66%) Query: 5 KKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKR 64 +KKKE E+ + E + E + +E+R+++R+E+E++++ + ++R+E+E + +++R Sbjct: 665 QKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQER 724 Query: 65 KRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKK 122 +R++++ + ERE +E E+ ++E+ + KKKK+ +++ E + ++++ +K K+ Sbjct: 725 RREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKE 782 Score = 68.6 bits (166), Expect = 1e-12 Identities = 35/125 (28%), Positives = 80/125 (64%), Gaps = 6/125 (4%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRK--EKRKEKRKEKEKKKKTKETEKRKEKEEE 58 ++K KKK ++ EE E ++EE+ + + ++ +E+R+ +E +K KE E+ + ++ Sbjct: 620 EEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAA 679 Query: 59 EKKR--KRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKR 116 E KR +++ ++++E+E R E+E E+E+ E+E+ E R+ +++RRR++E + +++ Sbjct: 680 EAKRLAEQREQERREQERR--EQERREQERREQERREQERQLAEQERRREQERLQAEREL 737 Query: 117 RRKTK 121 + + K Sbjct: 738 QEREK 742 Score = 68.6 bits (166), Expect = 1e-12 Identities = 29/123 (23%), Positives = 84/123 (68%), Gaps = 3/123 (2%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 ++++++++ E ++ +E E+E ++ ++ E+R+++ ++++ +E E+R+++ E++ Sbjct: 652 QQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQE 711 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120 +R+++R+ ++E RE+E + E E +E EK R +K++ +R+ EE++KK++++R Sbjct: 712 RREQERQLAEQERRREQERLQAERELQEREK---ALRLQKEQLQRELEEKKKKEEQQRLA 768 Query: 121 KKK 123 +++ Sbjct: 769 ERQ 771 Score = 67.8 bits (164), Expect = 2e-12 Identities = 38/137 (27%), Positives = 83/137 (60%), Gaps = 19/137 (13%) Query: 5 KKKKETEETEETEETEEEEEKEGKRK--------EKRKEKRKEKEKKKKTKETEKRKEKE 56 ++++E +E + ++EEE+E RK E+R+++R+E+E++++ + ++R+E+E Sbjct: 652 QQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQE 711 Query: 57 EEEKKRKRKRKKKKEEEEREEEEEEEEE-------EKEEEEKEEGRRRKKKKKRRRKE-- 107 E++R+ ++++ E+ER + E E +E +KE+ ++E ++KK++++R E Sbjct: 712 RREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQ 771 Query: 108 --EEEEKKKKRRRKTKK 122 EE+EKK K K Sbjct: 772 LQEEQEKKAKEAAGASK 788 Score = 66.2 bits (160), Expect = 6e-12 Identities = 35/132 (26%), Positives = 76/132 (57%), Gaps = 9/132 (6%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 +K++++ + EE E+ ++ +E KR+ + K K +E+ +K + +R E+ +EEK Sbjct: 536 EKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEK 595 Query: 61 KRK---------RKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEE 111 K++ K +K KEE EE+ +++ K+ EE E R+++++ +R R ++EE Sbjct: 596 KKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEE 655 Query: 112 KKKKRRRKTKKK 123 ++++ + +KK Sbjct: 656 EERRHQELLQKK 667 Score = 28.1 bits (61), Expect = 1.8 Identities = 17/56 (30%), Positives = 30/56 (53%), Gaps = 5/56 (8%) Query: 73 EEREEEEE-----EEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123 EE +EE E E +E E K ++ ++KK+R ++E + RRR +++K Sbjct: 35 EEIQEEAERMFTREFSKEPELMPKTPSQKNRRKKRRISYVQDENRDPIRRRLSRRK 90 Score = 27.3 bits (59), Expect = 3.0 Identities = 14/70 (20%), Positives = 32/70 (45%) Query: 31 EKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEE 90 E+ +E+ + ++ +KE E + ++ +RK++R ++E R+ K Sbjct: 35 EEIQEEAERMFTREFSKEPELMPKTPSQKNRRKKRRISYVQDENRDPIRRRLSRRKSRSS 94 Query: 91 KEEGRRRKKK 100 + RR + K Sbjct: 95 QLSSRRLRSK 104 Score = 26.6 bits (57), Expect = 5.1 Identities = 16/75 (21%), Positives = 33/75 (44%), Gaps = 5/75 (6%) Query: 17 EETEEEEEKE-----GKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKE 71 EE +EE E+ K E + +K ++KK + + + E + ++R +RK + Sbjct: 35 EEIQEEAERMFTREFSKEPELMPKTPSQKNRRKKRRISYVQDENRDPIRRRLSRRKSRSS 94 Query: 72 EEEREEEEEEEEEEK 86 + ++ EK Sbjct: 95 QLSSRRLRSKDSVEK 109 Score = 26.2 bits (56), Expect = 6.7 Identities = 12/38 (31%), Positives = 21/38 (55%) Query: 48 ETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEE 85 +T++ E + +RKR K+ E +EE+ E+EE Sbjct: 433 KTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEE 470 >gi|102467242 inner centromere protein antigens 135/155kDa isoform 2 [Homo sapiens] Length = 914 Score = 79.3 bits (194), Expect = 7e-16 Identities = 41/136 (30%), Positives = 86/136 (63%), Gaps = 13/136 (9%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEK---EE 57 KKK+ ++K + E+TE+ +EE E K K+K K+ E+ + ++ +E E R+ + +E Sbjct: 591 KKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQE 650 Query: 58 EEKKRKRKRKKKKEEEEREE----------EEEEEEEEKEEEEKEEGRRRKKKKKRRRKE 107 EE++R ++ +KK+EEE+E E+ E+E +E+E +E+ RR ++++++ R+E Sbjct: 651 EEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERRE 710 Query: 108 EEEEKKKKRRRKTKKK 123 +E + ++ RR+ +++ Sbjct: 711 QERQLAEQERRREQER 726 Score = 76.3 bits (186), Expect = 6e-15 Identities = 35/118 (29%), Positives = 74/118 (62%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61 KKK K+ EE E + EEE + +++ +E+R ++ +KK +E ++R K E K+ Sbjct: 620 KKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKR 679 Query: 62 RKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRK 119 +R++++ E+ER E+E E+E +E+E +E+ R+ ++++RR +E + +++ + R+ Sbjct: 680 LAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQERE 737 Score = 73.2 bits (178), Expect = 5e-14 Identities = 37/131 (28%), Positives = 79/131 (60%), Gaps = 8/131 (6%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRK--------EKRKEKRKEKEKKKKTKETEKR 52 K++++ +K + E E+ +EE++K+ ++K EK KE+R +EK KK +K Sbjct: 569 KREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKM 628 Query: 53 KEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEK 112 +E E K+ + R+ + ++E EE +E +K++EE++E R+ + KR ++ E+E+ Sbjct: 629 EEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQER 688 Query: 113 KKKRRRKTKKK 123 +++ RR+ +++ Sbjct: 689 REQERREQERR 699 Score = 72.0 bits (175), Expect = 1e-13 Identities = 31/123 (25%), Positives = 83/123 (67%), Gaps = 2/123 (1%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 KKK+++++ + E + E+ E+E + +E+R+++R+E+E++++ + ++R+ E+E + Sbjct: 662 KKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERR 721 Query: 61 KRKRKRKKKKEEEEREE--EEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRR 118 + + + + ++E +ERE+ ++E+ ++E EEK++ +++ +R+ +EE+E+K K+ Sbjct: 722 REQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAG 781 Query: 119 KTK 121 +K Sbjct: 782 ASK 784 Score = 71.6 bits (174), Expect = 1e-13 Identities = 30/118 (25%), Positives = 78/118 (66%) Query: 5 KKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKR 64 +KKKE E+ + E + E + +E+R+++R+E+E++++ + ++R+E+E + +++R Sbjct: 661 QKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQER 720 Query: 65 KRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKK 122 +R++++ + ERE +E E+ ++E+ + KKKK+ +++ E + ++++ +K K+ Sbjct: 721 RREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKE 778 Score = 68.6 bits (166), Expect = 1e-12 Identities = 35/125 (28%), Positives = 80/125 (64%), Gaps = 6/125 (4%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRK--EKRKEKRKEKEKKKKTKETEKRKEKEEE 58 ++K KKK ++ EE E ++EE+ + + ++ +E+R+ +E +K KE E+ + ++ Sbjct: 616 EEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAA 675 Query: 59 EKKR--KRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKR 116 E KR +++ ++++E+E R E+E E+E+ E+E+ E R+ +++RRR++E + +++ Sbjct: 676 EAKRLAEQREQERREQERR--EQERREQERREQERREQERQLAEQERRREQERLQAEREL 733 Query: 117 RRKTK 121 + + K Sbjct: 734 QEREK 738 Score = 68.6 bits (166), Expect = 1e-12 Identities = 29/123 (23%), Positives = 84/123 (68%), Gaps = 3/123 (2%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 ++++++++ E ++ +E E+E ++ ++ E+R+++ ++++ +E E+R+++ E++ Sbjct: 648 QQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQE 707 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120 +R+++R+ ++E RE+E + E E +E EK R +K++ +R+ EE++KK++++R Sbjct: 708 RREQERQLAEQERRREQERLQAERELQEREK---ALRLQKEQLQRELEEKKKKEEQQRLA 764 Query: 121 KKK 123 +++ Sbjct: 765 ERQ 767 Score = 67.8 bits (164), Expect = 2e-12 Identities = 38/137 (27%), Positives = 83/137 (60%), Gaps = 19/137 (13%) Query: 5 KKKKETEETEETEETEEEEEKEGKRK--------EKRKEKRKEKEKKKKTKETEKRKEKE 56 ++++E +E + ++EEE+E RK E+R+++R+E+E++++ + ++R+E+E Sbjct: 648 QQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQE 707 Query: 57 EEEKKRKRKRKKKKEEEEREEEEEEEEE-------EKEEEEKEEGRRRKKKKKRRRKE-- 107 E++R+ ++++ E+ER + E E +E +KE+ ++E ++KK++++R E Sbjct: 708 RREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQ 767 Query: 108 --EEEEKKKKRRRKTKK 122 EE+EKK K K Sbjct: 768 LQEEQEKKAKEAAGASK 784 Score = 66.2 bits (160), Expect = 6e-12 Identities = 35/132 (26%), Positives = 76/132 (57%), Gaps = 9/132 (6%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 +K++++ + EE E+ ++ +E KR+ + K K +E+ +K + +R E+ +EEK Sbjct: 532 EKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEK 591 Query: 61 KRK---------RKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEE 111 K++ K +K KEE EE+ +++ K+ EE E R+++++ +R R ++EE Sbjct: 592 KKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEE 651 Query: 112 KKKKRRRKTKKK 123 ++++ + +KK Sbjct: 652 EERRHQELLQKK 663 Score = 59.7 bits (143), Expect = 5e-10 Identities = 34/117 (29%), Positives = 65/117 (55%), Gaps = 4/117 (3%) Query: 6 KKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRK 65 K+KE + E EE E+ +R++ ++KR+ E+ K +E RK + E+ + K Sbjct: 531 KEKERQRLENLRRKEEAEQL--RRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMK 588 Query: 66 RKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKK 122 +KKK+ E++ + +E+ E+ +EE E + KKK +K EE E ++K+ + ++ Sbjct: 589 EEKKKQIEQKFAQIDEKTEKAKEERLAE--EKAKKKAAAKKMEEVEARRKQEEEARR 643 Score = 57.8 bits (138), Expect = 2e-09 Identities = 29/102 (28%), Positives = 61/102 (59%) Query: 21 EEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEE 80 + +EKE +R E + K + ++ +++ E +KR+ EE + KR+ + +K + ER E+ + Sbjct: 529 DPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMK 588 Query: 81 EEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKK 122 EE++++ E++ + + +K K R EE+ KKK +K ++ Sbjct: 589 EEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEE 630 Score = 49.3 bits (116), Expect = 7e-07 Identities = 28/101 (27%), Positives = 57/101 (56%), Gaps = 8/101 (7%) Query: 29 RKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEE--------REEEEE 80 R + ++++R+ E ++ +E E+ + ++ EE KR+R + K + EE RE E+ Sbjct: 527 RMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQ 586 Query: 81 EEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTK 121 +EE+K++ E++ + +K +K + + EEK KK+ K Sbjct: 587 MKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKK 627 Score = 45.4 bits (106), Expect = 1e-05 Identities = 24/73 (32%), Positives = 44/73 (60%), Gaps = 3/73 (4%) Query: 47 KETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEE---KEEGRRRKKKKKR 103 + T R + +E+E++R ++K+E E+ ++ EE++ + EE K E R RK + R Sbjct: 522 RNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQAR 581 Query: 104 RRKEEEEEKKKKR 116 R E+ +E+KKK+ Sbjct: 582 ERVEQMKEEKKKQ 594 Score = 44.3 bits (103), Expect = 2e-05 Identities = 31/102 (30%), Positives = 54/102 (52%), Gaps = 10/102 (9%) Query: 32 KRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRK---RKKKKEEEEREEEEEEEEEEKEE 88 KR + K+K+ + E + KEE E+ R++K K+++ EE + + EE + + Sbjct: 521 KRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQA 580 Query: 89 EEKEEGRRRKKKKKRRRK----EEEEEKKKKRR---RKTKKK 123 E+ E + +KKK+ +K +E+ EK K+ R K KKK Sbjct: 581 RERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKK 622 Score = 28.1 bits (61), Expect = 1.8 Identities = 17/56 (30%), Positives = 30/56 (53%), Gaps = 5/56 (8%) Query: 73 EEREEEEE-----EEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123 EE +EE E E +E E K ++ ++KK+R ++E + RRR +++K Sbjct: 35 EEIQEEAERMFTREFSKEPELMPKTPSQKNRRKKRRISYVQDENRDPIRRRLSRRK 90 Score = 27.3 bits (59), Expect = 3.0 Identities = 14/70 (20%), Positives = 32/70 (45%) Query: 31 EKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEE 90 E+ +E+ + ++ +KE E + ++ +RK++R ++E R+ K Sbjct: 35 EEIQEEAERMFTREFSKEPELMPKTPSQKNRRKKRRISYVQDENRDPIRRRLSRRKSRSS 94 Query: 91 KEEGRRRKKK 100 + RR + K Sbjct: 95 QLSSRRLRSK 104 Score = 26.6 bits (57), Expect = 5.1 Identities = 16/75 (21%), Positives = 33/75 (44%), Gaps = 5/75 (6%) Query: 17 EETEEEEEKE-----GKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKE 71 EE +EE E+ K E + +K ++KK + + + E + ++R +RK + Sbjct: 35 EEIQEEAERMFTREFSKEPELMPKTPSQKNRRKKRRISYVQDENRDPIRRRLSRRKSRSS 94 Query: 72 EEEREEEEEEEEEEK 86 + ++ EK Sbjct: 95 QLSSRRLRSKDSVEK 109 Score = 26.2 bits (56), Expect = 6.7 Identities = 12/38 (31%), Positives = 21/38 (55%) Query: 48 ETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEE 85 +T++ E + +RKR K+ E +EE+ E+EE Sbjct: 433 KTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEE 470 >gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sapiens] Length = 570 Score = 79.0 bits (193), Expect = 9e-16 Identities = 42/128 (32%), Positives = 88/128 (68%), Gaps = 7/128 (5%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKE---- 56 +K++K +++ E E EE E E++ +EK +E+ +++++++K +E EKR+E+E Sbjct: 327 EKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMW 386 Query: 57 -EEEKKRKRKRKKKKEEEEREEEEEE--EEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKK 113 +EEK R+++ K +++EE +E+EE+ E+EEK E++EE + +++K +R+ ++ E++K Sbjct: 387 RQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEK 446 Query: 114 KKRRRKTK 121 K R ++ K Sbjct: 447 KIREQEEK 454 Score = 76.3 bits (186), Expect = 6e-15 Identities = 34/123 (27%), Positives = 88/123 (71%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 +++K +++E + E+ E +E+EEK G+++EK E+ +E +++++ ++ K +E+E+K Sbjct: 388 QEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKK 447 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120 R+++ K +++EE +E+EE+ E++ + ++E + +++++K RR+EE+ +++K+ R+ Sbjct: 448 IREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQ 507 Query: 121 KKK 123 ++K Sbjct: 508 EEK 510 Score = 73.6 bits (179), Expect = 4e-14 Identities = 34/123 (27%), Positives = 86/123 (69%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 ++KK +++E + E+ E +E+EEK G+++ K E+ + +++++ ++ K +E+E+K Sbjct: 444 QEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKK 503 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120 R+++ K +++EE +E+EE+ E++E+ ++E + +++++K RR+EE+ +++ R R+ Sbjct: 504 IREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQ 563 Query: 121 KKK 123 ++K Sbjct: 564 EEK 566 Score = 73.2 bits (178), Expect = 5e-14 Identities = 35/128 (27%), Positives = 87/128 (67%), Gaps = 5/128 (3%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEE--- 57 +K++K ++ E+ E E+ E+EEK + ++ R+++++++++ K ++ EK +E+EE Sbjct: 341 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 400 Query: 58 --EEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKK 115 EE ++++ K ++EE+ E+EEE +E++E+ ++E + R+++KK R +EE+ ++++ Sbjct: 401 EQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEE 460 Query: 116 RRRKTKKK 123 ++ ++K Sbjct: 461 MMQEQEEK 468 Score = 71.6 bits (174), Expect = 1e-13 Identities = 37/127 (29%), Positives = 85/127 (66%), Gaps = 5/127 (3%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEE--- 57 +++K +++E E+ E+ +EE +++EK +E ++ +++K +E E+++++EE Sbjct: 314 QEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIR 373 Query: 58 EEKKRKRKRKK--KKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKK 115 E++KR+ + K ++EE+ RE+EE+ E+E+ +E+EE +++K ++EE +E+++K Sbjct: 374 EQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEK 433 Query: 116 RRRKTKK 122 RR+ +K Sbjct: 434 MRRQEEK 440 Score = 71.6 bits (174), Expect = 1e-13 Identities = 34/124 (27%), Positives = 85/124 (68%), Gaps = 2/124 (1%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 ++++K +++ E+ E E+ E+E++ + +E+ ++++EK +++ K E+ + +E+E+ Sbjct: 429 EQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEE 488 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEE--EEKEEGRRRKKKKKRRRKEEEEEKKKKRRR 118 K +R+ +K +E+E++ E+EE+ E+EE +E+EE +++K ++E+ +E+++K RR Sbjct: 489 KMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRR 548 Query: 119 KTKK 122 + +K Sbjct: 549 QEEK 552 Score = 71.2 bits (173), Expect = 2e-13 Identities = 39/127 (30%), Positives = 85/127 (66%), Gaps = 5/127 (3%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKE---E 57 K ++++KK E+ E+ E EE +++ ++ +++ K E+E K + +E + R+++E E Sbjct: 440 KIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIRE 499 Query: 58 EEKKRKRKRKKKKEEEEREEEEEEEEEEKEEE--EKEEGRRRKKKKKRRRKEEEEEKKKK 115 +EKK + + +K +E+EE +E+EE+ E+EE+ E+EE + +++K RR++E+ E++ + Sbjct: 500 QEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVR 559 Query: 116 RRRKTKK 122 R++ +K Sbjct: 560 LRQQEEK 566 Score = 70.9 bits (172), Expect = 2e-13 Identities = 38/136 (27%), Positives = 85/136 (62%), Gaps = 17/136 (12%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEK-------------RKEKEKKKKTK 47 +++++K++E E+ E E+ +E+E K +++EK +E+ ++EK +++ K Sbjct: 360 REQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEK 419 Query: 48 ETEKRKEKEEEEKKRKRKRKKKKEEE----EREEEEEEEEEEKEEEEKEEGRRRKKKKKR 103 E+ +E +E+E+K +R+ +K +E+E E+EE+ E+EE +E+E++ G + K ++ Sbjct: 420 MWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQ 479 Query: 104 RRKEEEEEKKKKRRRK 119 K +E+E+K +R+ + Sbjct: 480 EAKMQEQEEKMRRQEE 495 Score = 68.9 bits (167), Expect = 9e-13 Identities = 36/128 (28%), Positives = 82/128 (64%), Gaps = 6/128 (4%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 ++++K ++ E+ +E EE E+E++ +R+E+ +++EK ++++ EK ++ E E+ Sbjct: 292 RQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEE 351 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEE------KEEGRRRKKKKKRRRKEEEEEKKK 114 K + K +++EE+R+EEE+ E+EK +E+ +EE R +++K R ++E +E+++ Sbjct: 352 KMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEE 411 Query: 115 KRRRKTKK 122 K + +K Sbjct: 412 KMGEQEEK 419 Score = 68.6 bits (166), Expect = 1e-12 Identities = 42/128 (32%), Positives = 79/128 (61%), Gaps = 12/128 (9%) Query: 7 KKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEE-EEKKRKRK 65 +KE + + E E+EEK + +EK E+ K +E+++K +E EK +E+E+ +E++ K Sbjct: 327 EKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMW 386 Query: 66 RKKKKEEEEREEEEEEEEEEKEEEEK-----------EEGRRRKKKKKRRRKEEEEEKKK 114 R+++K E+ E+ E+EE +E+EEK EE + +++K RR++E+ E++K Sbjct: 387 RQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEK 446 Query: 115 KRRRKTKK 122 K R + +K Sbjct: 447 KIREQEEK 454 Score = 66.6 bits (161), Expect = 4e-12 Identities = 37/126 (29%), Positives = 82/126 (65%), Gaps = 5/126 (3%) Query: 3 KKKKKKETEETEETEETEEE-EEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEK---EEE 58 +++++K + E+ +E EE+ +E+E K +E+ ++ R+++E + +E +R+E+ E+E Sbjct: 284 QQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKE 343 Query: 59 EKKRKRKRKKKKEEEEREEEEEEEEEEK-EEEEKEEGRRRKKKKKRRRKEEEEEKKKKRR 117 EK R+ + K ++E+ RE+EE+ +EEEK E+EK + + K ++ + E+EEK +++ Sbjct: 344 EKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQE 403 Query: 118 RKTKKK 123 +++ Sbjct: 404 EMMQEQ 409 Score = 65.9 bits (159), Expect = 8e-12 Identities = 33/117 (28%), Positives = 75/117 (64%), Gaps = 2/117 (1%) Query: 5 KKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEK--EKKKKTKETEKRKEKEEEEKKR 62 K + + EE E +++E++ R+E++ ++R+EK E+++K +E E++ ++EE Sbjct: 268 KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWE 327 Query: 63 KRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRK 119 K ++ +++EE E+EE+ E E++ E+E+ R +++K++ K E+EK++++ K Sbjct: 328 KEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK 384 Score = 65.1 bits (157), Expect = 1e-11 Identities = 29/115 (25%), Positives = 78/115 (67%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 +K +++++ +E EE + +EE+ +E + K +R+E+ ++++K ++ E EKEE+ + Sbjct: 288 EKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIR 347 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKK 115 + + K ++++ E+EE+ +EEE+ +E+E+++E + +++ + +E+EE+ +++ Sbjct: 348 ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQ 402 Score = 55.1 bits (131), Expect = 1e-08 Identities = 27/116 (23%), Positives = 68/116 (58%) Query: 8 KETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRK 67 KE + + + EE + R +++E++ ++++K + EK +E+EE+ ++++ K + Sbjct: 260 KELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMR 319 Query: 68 KKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123 +++E +EE+ +EE E++E+ R ++K + K E+E+K++ K +++ Sbjct: 320 RQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ 375 Score = 49.7 bits (117), Expect = 6e-07 Identities = 41/130 (31%), Positives = 77/130 (59%), Gaps = 13/130 (10%) Query: 1 KKKKKKKKETEETEETEETEEE-EEKEGKRKEKRK-----EKRKEKEKKKKTKETE---- 50 K+K K +E + E+E++E + KE KRK +R +++ + E KE + Sbjct: 208 KEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSA 267 Query: 51 KRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEE 110 K + + EE + R ++++E+ R+EE+ +E EEK +E++E + R++++K RR+EE Sbjct: 268 KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEE--KIREQEEKMRRQEEMM 325 Query: 111 -EKKKKRRRK 119 EK++K RR+ Sbjct: 326 WEKEEKMRRQ 335 Score = 49.3 bits (116), Expect = 7e-07 Identities = 30/122 (24%), Positives = 70/122 (57%), Gaps = 2/122 (1%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 K+ K+K + + ++ + E + GK E + K + + ++ + + +++EE+ Sbjct: 233 KELKRKLERAKLLLPQQQLQAEADHLGK--ELQSVSAKLQAQVEENELWNRLNQQQEEKM 290 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120 R+ ++ +++EE+ +E+EE+ E+E++ +EE K++K RR++E EK++K R Sbjct: 291 WRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELE 350 Query: 121 KK 122 +K Sbjct: 351 EK 352 Score = 39.7 bits (91), Expect = 6e-04 Identities = 36/143 (25%), Positives = 70/143 (48%), Gaps = 21/143 (14%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRK-EKEEEE 59 +KKK + E T+E + E + E+ KEK + ++K + E+EK + + +E Sbjct: 175 QKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKE 234 Query: 60 KKRKRKRKKK---------------KEEEEREEEEEEEEEEKE-----EEEKEEGRRRKK 99 KRK +R K KE + + + + EE E +++EE R++ Sbjct: 235 LKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQE 294 Query: 100 KKKRRRKEEEEEKKKKRRRKTKK 122 +K + R+E+ +E+++K R + +K Sbjct: 295 EKIQEREEKIQEQEEKIREQEEK 317 >gi|239745093 PREDICTED: hypothetical protein XP_002343359 [Homo sapiens] Length = 142 Score = 78.6 bits (192), Expect = 1e-15 Identities = 37/76 (48%), Positives = 56/76 (73%) Query: 37 RKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRR 96 RK + +++K +E ++R+EK EEK+R+ KR++K+EE+E EEEEEEEEEE+EEEE+EE Sbjct: 63 RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVS 122 Query: 97 RKKKKKRRRKEEEEEK 112 + R E EE++ Sbjct: 123 FSLATRERETETEEKR 138 Score = 73.9 bits (180), Expect = 3e-14 Identities = 37/81 (45%), Positives = 56/81 (69%), Gaps = 5/81 (6%) Query: 33 RKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKE 92 RK +R+E++++++ + EKR+E++ E KR+ K ++K+EEEE EEEEEEEEEE+EEEE Sbjct: 63 RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVS 122 Query: 93 EGRRRKKKKKRRRKEEEEEKK 113 R R+ E EEK+ Sbjct: 123 -----FSLATRERETETEEKR 138 Score = 69.7 bits (169), Expect = 5e-13 Identities = 34/76 (44%), Positives = 53/76 (69%), Gaps = 1/76 (1%) Query: 42 KKKKTKETEKRKEKEEEEKKRKRKRKK-KKEEEEREEEEEEEEEEKEEEEKEEGRRRKKK 100 +K + +E ++R+EK EEK+R+ KR++ K+ E+E E+EEEEEEEE+EEEE+EE + Sbjct: 63 RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVS 122 Query: 101 KKRRRKEEEEEKKKKR 116 +E E E ++KR Sbjct: 123 FSLATRERETETEEKR 138 Score = 68.2 bits (165), Expect = 2e-12 Identities = 36/90 (40%), Positives = 55/90 (61%), Gaps = 11/90 (12%) Query: 16 TEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEER 75 T + + +E +R+EKR+E+++ +EK+++ K EK +EKEEEE EEEE Sbjct: 60 TSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEE-----------EEEEE 108 Query: 76 EEEEEEEEEEKEEEEKEEGRRRKKKKKRRR 105 EEEEEEEEEE+E R R+ + + +R Sbjct: 109 EEEEEEEEEEEEVSFSLATRERETETEEKR 138 Score = 58.5 bits (140), Expect = 1e-09 Identities = 25/75 (33%), Positives = 50/75 (66%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 K +++++K EE E+ EE+ +EGKR+EK +EK +E+E++++ +E E+ +E+EE Sbjct: 64 KSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSF 123 Query: 61 KRKRKRKKKKEEEER 75 + ++ + EE+R Sbjct: 124 SLATRERETETEEKR 138 Score = 56.2 bits (134), Expect = 6e-09 Identities = 28/75 (37%), Positives = 49/75 (65%), Gaps = 1/75 (1%) Query: 5 KKKKETEETEETEETEEEEEKEGKRKE-KRKEKRKEKEKKKKTKETEKRKEKEEEEKKRK 63 +K + EE E+ EE+ +E KR+E KR+EK +EKE++++ +E E+ +E+EEEE++ Sbjct: 63 RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVS 122 Query: 64 RKRKKKKEEEEREEE 78 ++ E E EE+ Sbjct: 123 FSLATRERETETEEK 137 Score = 55.5 bits (132), Expect = 1e-08 Identities = 27/74 (36%), Positives = 47/74 (63%), Gaps = 1/74 (1%) Query: 49 TEKRKEKEEEEKKRKRKRKK-KKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKE 107 T RK + EEK+R+ KR++ K+ EE+R E + E+EE++EEE+EE +++++ +E Sbjct: 60 TSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEE 119 Query: 108 EEEEKKKKRRRKTK 121 E R R+T+ Sbjct: 120 EVSFSLATRERETE 133 Score = 52.4 bits (124), Expect = 9e-08 Identities = 19/57 (33%), Positives = 42/57 (73%) Query: 67 KKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123 +K + EE+ EE+ EE++ EE++ EG+RR+K++++ +EEEEE++++ + +++ Sbjct: 63 RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEE 119 Score = 52.0 bits (123), Expect = 1e-07 Identities = 21/58 (36%), Positives = 41/58 (70%) Query: 66 RKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123 RK ++ EE+R EE+ EE+ +EE+ +E RR K+++K +EEEEE++++ + +++ Sbjct: 63 RKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEE 120 Score = 47.0 bits (110), Expect = 4e-06 Identities = 23/70 (32%), Positives = 41/70 (58%), Gaps = 1/70 (1%) Query: 55 KEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRR-KKKKKRRRKEEEEEKK 113 KEE R + +R EE+ EE+ +EE+ +EE RR K+++K KEEEEE++ Sbjct: 47 KEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEE 106 Query: 114 KKRRRKTKKK 123 ++ + +++ Sbjct: 107 EEEEEEEEEE 116 Score = 42.0 bits (97), Expect = 1e-04 Identities = 17/75 (22%), Positives = 41/75 (54%) Query: 49 TEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEE 108 T +EE + + + EE+ EE++ EE++ E +RR+ K++ + +E+ Sbjct: 40 TNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEK 99 Query: 109 EEEKKKKRRRKTKKK 123 EEE++++ + +++ Sbjct: 100 EEEEEEEEEEEEEEE 114 >gi|27734775 hypothetical protein LOC286499 [Homo sapiens] Length = 248 Score = 78.2 bits (191), Expect = 1e-15 Identities = 41/140 (29%), Positives = 78/140 (55%), Gaps = 17/140 (12%) Query: 1 KKKKKKKKE---------TEETEETEETEEEEEKEGKRKEKRKEKR--------KEKEKK 43 +KKK+KKK ++ + + ++E+EE+K+GKR++K+K + E E + Sbjct: 93 RKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESE 152 Query: 44 KKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKR 103 K +K+K K+E EK++ + KK ++ +++ E E + EE + KKK++ Sbjct: 153 SKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRC 212 Query: 104 RRKEEEEEKKKKRRRKTKKK 123 +E+ +EK KK+++K KK Sbjct: 213 EEREQAKEKVKKKKKKQHKK 232 Score = 65.9 bits (159), Expect = 8e-12 Identities = 33/121 (27%), Positives = 68/121 (56%), Gaps = 4/121 (3%) Query: 3 KKKKKKETEETEETEETEEEEEKEGKRKEKRKEK-RKEKEKKKKTKETEKRKEKEEEEKK 61 K++KKK+ + ++ + E E E K K+K+K + E EK+K + K+++K + K Sbjct: 129 KRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDK 188 Query: 62 RKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTK 121 + E EE+ + ++++ EE+E+ + + KKKK+++ ++ +KKKK+ + Sbjct: 189 ---PLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKKKKSGSSH 245 Query: 122 K 122 K Sbjct: 246 K 246 Score = 65.1 bits (157), Expect = 1e-11 Identities = 37/122 (30%), Positives = 63/122 (51%), Gaps = 4/122 (3%) Query: 1 KKKKKKKKETEET-EETEETEEEEEKEGKRKEKRKEKR-KEKEKKKKTKETEKRKEKEEE 58 K + KKE E++ E+ E K+ +RK+KRK+K + + + + E+E Sbjct: 64 KMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDE 123 Query: 59 EKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRR 118 EKK+ ++RKKKK + + E E E KE +++KK K KE++ K+R+ Sbjct: 124 EKKQGKRRKKKKNRSYKSSQSSTHESESES--KESVKKKKKSKDETEKEKDVRSLSKKRK 181 Query: 119 KT 120 K+ Sbjct: 182 KS 183 Score = 64.3 bits (155), Expect = 2e-11 Identities = 41/123 (33%), Positives = 61/123 (49%), Gaps = 13/123 (10%) Query: 14 EETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKE-KEEEEKKRKRKRKKKKEE 72 EE ++ E ++ K + +EK E KK+ K EK E KKR+RK+K+KK+ Sbjct: 42 EEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKS 101 Query: 73 -----EEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRK-------EEEEEKKKKRRRKT 120 + + E+EEK++G+RRKKKK R K E E E K+ ++K Sbjct: 102 CRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKK 161 Query: 121 KKK 123 K K Sbjct: 162 KSK 164 Score = 41.2 bits (95), Expect = 2e-04 Identities = 28/100 (28%), Positives = 50/100 (50%), Gaps = 22/100 (22%) Query: 45 KTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEE---EEKEEGRRRKKKK 101 + + T + +K+ E KK K + EE+ E ++E E+ +E+ + ++R++KK Sbjct: 36 RPRPTWEEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKK 95 Query: 102 KRRRK-------------------EEEEEKKKKRRRKTKK 122 KR++K E+EEKK+ +RRK KK Sbjct: 96 KRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKK 135 >gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 750 Score = 77.8 bits (190), Expect = 2e-15 Identities = 36/123 (29%), Positives = 90/123 (73%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 +++K +++E + E+ E T+E+EEK G+++EK E+ ++ +++++T ++ K +E+E+K Sbjct: 624 QEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKK 683 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120 R+++ K +++EE +E+EE+ E++E+ ++E + +++++K RR+EE+ +++ R R+ Sbjct: 684 IREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQ 743 Query: 121 KKK 123 ++K Sbjct: 744 EEK 746 Score = 75.1 bits (183), Expect = 1e-14 Identities = 44/137 (32%), Positives = 88/137 (64%), Gaps = 15/137 (10%) Query: 1 KKKKKKKKET------EETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEK--- 51 K++K +++E E+ E EE E+EK +++EKR+E+ K +E++K+ ++ K Sbjct: 375 KEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWR 434 Query: 52 --RKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKR----RR 105 K +E+EEK R++++K ++EE+ E+E+ EEEK +E++E R+ +K ++ R+ Sbjct: 435 QEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQ 494 Query: 106 KEEEEEKKKKRRRKTKK 122 KE+ E+++K R++ +K Sbjct: 495 KEKMHEQEEKIRKQEEK 511 Score = 72.4 bits (176), Expect = 8e-14 Identities = 41/130 (31%), Positives = 89/130 (68%), Gaps = 8/130 (6%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEK---RKEKRKEKEKKKKTKETEKRKEKE- 56 +++K++++E + + E+ E+EEK +++EK ++EKR+E+E+K +E + R+++E Sbjct: 561 EEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEK 620 Query: 57 --EEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEE--EKEEGRRRKKKKKRRRKEEEEEK 112 E+E+K + + +K +E+EE +E+EE+ E+EE+ E+EE + +++ R++E+ E+ Sbjct: 621 IQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQ 680 Query: 113 KKKRRRKTKK 122 +KK R + +K Sbjct: 681 EKKIREQEEK 690 Score = 71.2 bits (173), Expect = 2e-13 Identities = 37/126 (29%), Positives = 87/126 (69%), Gaps = 5/126 (3%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKE--KEKKKKTKETEKRKEKE-- 56 +++++K++E E+ E E+ +E+E K +++EK +E+ ++ +++KK ++ EK E+E Sbjct: 407 REQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKI 466 Query: 57 -EEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKK 115 EEEK+++++ ++EE+ E+EE ++EK E++E+ R++++K R+ ++ E+++K Sbjct: 467 REEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKI 526 Query: 116 RRRKTK 121 R ++ K Sbjct: 527 REQEEK 532 Score = 71.2 bits (173), Expect = 2e-13 Identities = 35/124 (28%), Positives = 85/124 (68%), Gaps = 2/124 (1%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 K+++K +++ E+ +E EE E+E++ + +E+ ++++EK +++ K E+ ++ +E+E+ Sbjct: 609 KQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEE 668 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEE--EEKEEGRRRKKKKKRRRKEEEEEKKKKRRR 118 R+ +K +E+E++ E+EE+ E+EE +E+EE +++K ++E+ +E+++K RR Sbjct: 669 TMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRR 728 Query: 119 KTKK 122 + +K Sbjct: 729 QEEK 732 Score = 70.5 bits (171), Expect = 3e-13 Identities = 42/126 (33%), Positives = 83/126 (65%), Gaps = 6/126 (4%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61 ++++K++E EE EE E+E+ ++KEK E+ ++ K+++ ++ K +E+EEK Sbjct: 467 REEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKI 526 Query: 62 RKRKRKKKKEEEEREEEEE--EEEEEKEEEEK--EEGRRRKKKKKRRRKEEE--EEKKKK 115 R+++ K ++EE+ E+EE EEE+ E+EK EE +R++++ K R+EE+ E+++K Sbjct: 527 REQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKV 586 Query: 116 RRRKTK 121 R++ K Sbjct: 587 WRQEEK 592 Score = 70.5 bits (171), Expect = 3e-13 Identities = 41/136 (30%), Positives = 91/136 (66%), Gaps = 14/136 (10%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKE--KEKKKKTKETEKRKEKEE-- 57 ++++K E E+ E E+ +E+E+K +++EK +E+ ++ ++++K ++ EKR+E+EE Sbjct: 548 REEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKM 607 Query: 58 ---EEKKRKRKRKKKKEEEEREEEEE---EEEEEKEEEEKEEGRRRKKKKKRRRKEEEEE 111 EEK R+++ K +++EE+ E+EE E+EE +E+E++ G + +K ++ K +E+E Sbjct: 608 WKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQE 667 Query: 112 ----KKKKRRRKTKKK 123 +++++ R+ +KK Sbjct: 668 ETMWRQEEKIREQEKK 683 Score = 70.5 bits (171), Expect = 3e-13 Identities = 37/124 (29%), Positives = 88/124 (70%), Gaps = 2/124 (1%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEK-RKEKRKEKEKKKKTKETEKRKEKEEEE 59 +++K ++E + E+ E+ +E+EEK K++EK R+++ K +E+++K +E E+ K +E+EE Sbjct: 582 QEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEE-KIREQEE 640 Query: 60 KKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRK 119 ++++ K ++EE+ E+EE+ +E++E ++E + R+++KK R +EE+ ++++ ++ Sbjct: 641 MTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQE 700 Query: 120 TKKK 123 ++K Sbjct: 701 QEEK 704 Score = 70.1 bits (170), Expect = 4e-13 Identities = 44/139 (31%), Positives = 92/139 (66%), Gaps = 16/139 (11%) Query: 1 KKKKKKKKETEETEETEETEEEEEK---EGKRKEKR----KEKRKEKEKKKKTKETEKRK 53 ++ ++K E E+ E EE +EEEK + KR+E+ +++ K +E+++K +E EK+ Sbjct: 394 RELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKM 453 Query: 54 EKEEE---EKKRKRKRKKKKEEEE--REEEEEEEEEE----KEEEEKEEGRRRKKKKKRR 104 ++EE E+++ R+ +K++E+EE R+EE+ E+EE KE+ ++E + RK+++K Sbjct: 454 WRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVW 513 Query: 105 RKEEEEEKKKKRRRKTKKK 123 R+EE+ +++++ R+ ++K Sbjct: 514 RQEEKIREQEEKIREQEEK 532 Score = 69.7 bits (169), Expect = 5e-13 Identities = 37/127 (29%), Positives = 85/127 (66%), Gaps = 6/127 (4%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEK---RKEKEE 57 +++K ++E + E+ E+ E+EEK +++EK +E+ + +++K E EK ++++E Sbjct: 508 QEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQE 567 Query: 58 EEKKRKRKRKKKKEEEE---REEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKK 114 +E K R+ +K +E+EE R+EE+ E+EEK +E++E+ ++++K + + ++ +E+++K Sbjct: 568 QEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEK 627 Query: 115 KRRRKTK 121 R ++ K Sbjct: 628 IREQEEK 634 Score = 69.3 bits (168), Expect = 7e-13 Identities = 40/131 (30%), Positives = 82/131 (62%), Gaps = 8/131 (6%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKR-KEKRKEKEKKKKTKETEKRKEKEE-- 57 +++K +K+E + + E+ E+EEK +++EK +++ K +E+++ +E EK E+E+ Sbjct: 501 QEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIW 560 Query: 58 EEKKRKRKRKKKKEEEEREEEEEE-----EEEEKEEEEKEEGRRRKKKKKRRRKEEEEEK 112 EE+KR+ + K +EE+ E+EE EE+ +E+EEK + + K K+ + E+EEK Sbjct: 561 EEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEK 620 Query: 113 KKKRRRKTKKK 123 +++ K +++ Sbjct: 621 IQEQEEKIREQ 631 Score = 69.3 bits (168), Expect = 7e-13 Identities = 37/128 (28%), Positives = 87/128 (67%), Gaps = 6/128 (4%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEE--- 57 ++++K ++ E+ E EE EEEK ++++ +E+++++++ K ++ EK +E+EE Sbjct: 528 EQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVW 587 Query: 58 --EEKKRKRKRKKKKEEEEREEEEEEEEEEKEE-EEKEEGRRRKKKKKRRRKEEEEEKKK 114 EEK R+++ K++++EE+ ++EE+ E++E+ +E+EE R +++K R ++E +E+++ Sbjct: 588 RQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEE 647 Query: 115 KRRRKTKK 122 K + +K Sbjct: 648 KMGEQEEK 655 Score = 68.9 bits (167), Expect = 9e-13 Identities = 37/128 (28%), Positives = 86/128 (67%), Gaps = 6/128 (4%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEK---EKKKKTKETEKRKEKEEE 58 ++++K +E EE + +E + E++E R+++ K +R+E+ EK++K + E+ ++EE Sbjct: 304 RQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 363 Query: 59 EKKRKRKRKKKKEEEEREEEE---EEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKK 115 + +R+ + +KEE+ R +EE E+EE+ +E EEK + + ++++ +R+EEE+ ++++ Sbjct: 364 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE 423 Query: 116 RRRKTKKK 123 +R++ + K Sbjct: 424 KRQEQEAK 431 Score = 68.9 bits (167), Expect = 9e-13 Identities = 36/131 (27%), Positives = 88/131 (67%), Gaps = 8/131 (6%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKE---- 56 +K++K +++ E E EE E E++ +EK +E+ +++++++K +E EKR+E+E Sbjct: 374 EKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMW 433 Query: 57 -EEEKKRKRKRKKKKEEEE---REEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEK 112 +EEK R+++ K +++E++ +EE+ E+E+ +EEE+++E +++++ ++EE + Sbjct: 434 RQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWR 493 Query: 113 KKKRRRKTKKK 123 +K++ + ++K Sbjct: 494 QKEKMHEQEEK 504 Score = 68.9 bits (167), Expect = 9e-13 Identities = 38/122 (31%), Positives = 85/122 (69%), Gaps = 4/122 (3%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKR-KEKRKEKEKKKKTKETEKRKEKEEEE 59 +++K +++E + + E+ E+EEK +++EK K++ K +E+++K +E E+ K +E+EE Sbjct: 575 QEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEE-KIREQEE 633 Query: 60 KKRKRKRKKKKEEEEREEEEEE--EEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRR 117 K R+++ +++EE+ E+EE+ E+EEK +E++E R+++K + + K+ E+++K R Sbjct: 634 KIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIRE 693 Query: 118 RK 119 ++ Sbjct: 694 QE 695 Score = 67.8 bits (164), Expect = 2e-12 Identities = 44/141 (31%), Positives = 94/141 (66%), Gaps = 18/141 (12%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEK---RKEKRKEKEKK------KKTKETEK 51 ++++K ++ E + E+ E+EEK K++EK ++EK +E+E+K K ++ EK Sbjct: 480 RQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEK 539 Query: 52 RKEKEE--EEKKRKRKRKKKKEEEEREEEEE----EEEEEKEEEEK---EEGRRRKKKKK 102 +E+EE E+++ +++K EEE+R+E+E+ +EE+ +E+EEK +E + R++++K Sbjct: 540 IREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEK 599 Query: 103 RRRKEEEEEKKKKRRRKTKKK 123 R+ +EE+ K++++ R+ ++K Sbjct: 600 RQEQEEKMWKQEEKIREQEEK 620 Score = 67.4 bits (163), Expect = 3e-12 Identities = 35/130 (26%), Positives = 81/130 (62%), Gaps = 9/130 (6%) Query: 3 KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEK---------EKKKKTKETEKRK 53 ++K +++ E+ E EE E+E++ +R+E+ +++EK EK++K + E+ Sbjct: 313 EEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMM 372 Query: 54 EKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKK 113 ++EE+ +R+ + +KEE+ RE EE+ E+EK E++E+ + +K +++ +++E+E K Sbjct: 373 WEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKM 432 Query: 114 KKRRRKTKKK 123 ++ K +++ Sbjct: 433 WRQEEKIREQ 442 Score = 67.4 bits (163), Expect = 3e-12 Identities = 42/132 (31%), Positives = 86/132 (65%), Gaps = 10/132 (7%) Query: 2 KKKKKKKETEETEETEETEEEEEK---EGKRKEKRKEKRKEKEKKKKTKETEKRKE---K 55 ++++K +E EE EE E+EK E KR+E+ + +++EK ++ +E R+E + Sbjct: 535 RQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIR 594 Query: 56 EEEEKKRKRKRKKKKEEEE-REEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKE---EEEE 111 E+EEK+++++ K K+EE+ RE+EE+ +E+E++ E+EE R +++ + ++E E+EE Sbjct: 595 EQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEE 654 Query: 112 KKKKRRRKTKKK 123 K ++ K +++ Sbjct: 655 KMCEQEEKMQEQ 666 Score = 67.0 bits (162), Expect = 3e-12 Identities = 33/123 (26%), Positives = 81/123 (65%), Gaps = 1/123 (0%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 K++K +++E E+ E+ +EE +++EK +E ++ +++K +E E++++ EEE+ Sbjct: 361 KEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQ-EEEKI 419 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120 + + KR++++ + R+EE+ E+EEK E++++ R+++K + K EEEK++++ Sbjct: 420 REQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMW 479 Query: 121 KKK 123 +++ Sbjct: 480 RQE 482 Score = 66.6 bits (161), Expect = 4e-12 Identities = 36/126 (28%), Positives = 83/126 (65%), Gaps = 6/126 (4%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKE---KRKEKRKEKEKKKKTKETEKRKEKE-- 56 ++K +++E + E+ E+ E+EEK +++E +++EK + +E+ KE + R+++E Sbjct: 313 EEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMM 372 Query: 57 -EEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKK 115 E+E+K +R+ + E+EE+ E EE+ E+E+ ++E +R++++K R +++ +E++ K Sbjct: 373 WEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKM 432 Query: 116 RRRKTK 121 R++ K Sbjct: 433 WRQEEK 438 Score = 66.6 bits (161), Expect = 4e-12 Identities = 38/128 (29%), Positives = 81/128 (63%), Gaps = 9/128 (7%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEK----RKEKRKEKEKKKKTKETEKRKEKE 56 ++++K +++ E+ EE E+E++ +R+E+ ++EK + +E+ KE + R+++E Sbjct: 325 EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEE 384 Query: 57 ----EEEKKRKRKRKKKKEEEEREEEEEEEEEEK-EEEEKEEGRRRKKKKKRRRKEEEEE 111 +EEK R+ + K ++E+ RE+EE+ +EEEK E+EK + + K ++ + E+EE Sbjct: 385 MMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEE 444 Query: 112 KKKKRRRK 119 K +++ +K Sbjct: 445 KIREQEKK 452 Score = 66.6 bits (161), Expect = 4e-12 Identities = 35/117 (29%), Positives = 74/117 (63%) Query: 3 KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKR 62 ++++K +E EE +E+E+ +++EK E+ + +K+K E E++ K+EE+ R Sbjct: 455 RQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWR 514 Query: 63 KRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRK 119 + ++ +++EE+ RE+EE+ +E++ E+EE R ++K + K EEEK++++ K Sbjct: 515 QEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDK 571 Score = 66.2 bits (160), Expect = 6e-12 Identities = 39/130 (30%), Positives = 84/130 (64%), Gaps = 7/130 (5%) Query: 1 KKKKKKKKETEETEETEET-EEEEEKEGKRKEK---RKEKRKEKEKKKKTKETEKRKEKE 56 ++++K ++ E+ +E EE +E+EEK +++EK ++EK + +E+ KE + R+++E Sbjct: 297 QQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEE 356 Query: 57 ---EEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKK 113 E+E+K +R+ + E+EE+ +EE EKEE+ +E + +++K R +EE+ +++ Sbjct: 357 MMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEE 416 Query: 114 KKRRRKTKKK 123 +K R + K++ Sbjct: 417 EKIREQEKRQ 426 Score = 66.2 bits (160), Expect = 6e-12 Identities = 39/131 (29%), Positives = 87/131 (66%), Gaps = 12/131 (9%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEK-RKEKRKEKEKKKKTKETEKR---KEKE 56 K++K +++E E+ E+ +EE +++EK R+++ EK++K +E E++ +EK Sbjct: 347 KEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKI 406 Query: 57 EEEKKRKRKRKKKKEEEEREEEE----EEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEK 112 E+++++++ +K +E+E+R+E+E +EE+ +E+EEK R+++KK R+EE+ + Sbjct: 407 REQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEK----IREQEKKMWRQEEKIHE 462 Query: 113 KKKRRRKTKKK 123 ++K R + K++ Sbjct: 463 QEKIREEEKRQ 473 Score = 65.9 bits (159), Expect = 8e-12 Identities = 34/124 (27%), Positives = 80/124 (64%), Gaps = 3/124 (2%) Query: 1 KKKKKKKKETEETEETEETEE---EEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEE 57 K +++++ E+ E+ EE E+E++ +R+E+ +++EK ++++ EK ++ E Sbjct: 336 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRE 395 Query: 58 EEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRR 117 E+K + K +++EE+R+EEE+ E+EK +E++ + R+++K + + ++ E++KK R Sbjct: 396 LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWR 455 Query: 118 RKTK 121 ++ K Sbjct: 456 QEEK 459 Score = 65.9 bits (159), Expect = 8e-12 Identities = 38/126 (30%), Positives = 84/126 (66%), Gaps = 5/126 (3%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKR---KEKRKEKEKKKKTKETEKRKEK-- 55 +++ K ++ E+ E EE E+EK+ R+E++ +EK +E+EK+++ +E +++EK Sbjct: 427 EQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIH 486 Query: 56 EEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKK 115 E+EE R++++ ++EE+ R++EE+ +E++ E+EE R +++K R++E+ E+++ Sbjct: 487 EQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEM 546 Query: 116 RRRKTK 121 R + K Sbjct: 547 WREEEK 552 Score = 65.1 bits (157), Expect = 1e-11 Identities = 34/127 (26%), Positives = 85/127 (66%), Gaps = 4/127 (3%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEK-RKEKRKEKEKKKKTKETEKRKEKEEEE 59 +++K++++E + ++ E+ E+EEK +++EK R+++ K +E+++ T+E E++ ++EE+ Sbjct: 596 QEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEK 655 Query: 60 KKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKE---EEEEKKKKR 116 + ++ +++EE +EE+ E+EK+ E+EE R +++ + ++E E+EEK ++ Sbjct: 656 MCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQ 715 Query: 117 RRKTKKK 123 K +++ Sbjct: 716 EEKMQEQ 722 Score = 63.9 bits (154), Expect = 3e-11 Identities = 35/125 (28%), Positives = 79/125 (63%), Gaps = 3/125 (2%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 +K +++++ E EE +EE E + K +R+E+ ++++K ++ E EKEE+ + Sbjct: 335 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIR 394 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRR---RKKKKKRRRKEEEEEKKKKRR 117 + + K ++++ E+EE+ +EEE+ +E+E+++E R+++K R ++E+ E++KK Sbjct: 395 ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMW 454 Query: 118 RKTKK 122 R+ +K Sbjct: 455 RQEEK 459 Score = 63.5 bits (153), Expect = 4e-11 Identities = 36/120 (30%), Positives = 75/120 (62%), Gaps = 2/120 (1%) Query: 5 KKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEK--EKKKKTKETEKRKEKEEEEKKR 62 K + + EE E +++E++ R+E++ ++ +EK E+++K +E E++ ++EE+ +R Sbjct: 280 KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRR 339 Query: 63 KRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKK 122 + + +KEE+ R +EE E+E++ +EE K++K RR++E EK++K R +K Sbjct: 340 QEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEK 399 Score = 61.6 bits (148), Expect = 1e-10 Identities = 34/119 (28%), Positives = 76/119 (63%), Gaps = 1/119 (0%) Query: 6 KKKETEETEETEETEEEEEKEGKRKEK-RKEKRKEKEKKKKTKETEKRKEKEEEEKKRKR 64 +++E + + E+ +E EEK +++EK R+++ K +E+++K + E+ ++EE+ +R+ Sbjct: 296 QQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQE 355 Query: 65 KRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123 + +KEE+ R +EE E+E++ +EE K++K R +E+ E++K R ++ K++ Sbjct: 356 EMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQ 414 Score = 57.0 bits (136), Expect = 4e-09 Identities = 33/112 (29%), Positives = 69/112 (61%), Gaps = 1/112 (0%) Query: 8 KETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRK 67 KE + + + EE + R +++E++ ++++K + EK +E+EE+ ++++ K + Sbjct: 272 KELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIR 331 Query: 68 KKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRK 119 +++E+ R+EE E+EEK + EE K++K RR++E EK++K RR+ Sbjct: 332 EQEEKMRRQEEMMWEKEEKMRRQ-EEMMWEKEEKMRRQEEMMWEKEEKMRRQ 382 Score = 49.3 bits (116), Expect = 7e-07 Identities = 33/126 (26%), Positives = 72/126 (57%), Gaps = 9/126 (7%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 K+ K+K + + ++ + E + GK E + K + + ++ + + +++EE+ Sbjct: 245 KELKRKLERAKLLLPQQQLQAEADHLGK--ELQSVSAKLQAQVEENELWNRLNQQQEEKM 302 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRR-------KKKKKRRRKEEEEEKK 113 R+ ++ ++ EE+ +E+EE+ E+E++ E+EE RR K++K RR++E EK+ Sbjct: 303 WRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKE 362 Query: 114 KKRRRK 119 +K RR+ Sbjct: 363 EKMRRQ 368 Score = 48.5 bits (114), Expect = 1e-06 Identities = 39/138 (28%), Positives = 73/138 (52%), Gaps = 22/138 (15%) Query: 1 KKKKKKKKETEETEETEETEEE-EEKEGKRKEKR------------------KEKRKEKE 41 K+K K +E + E+E++E + KE KRK +R KE + Sbjct: 220 KEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSA 279 Query: 42 KKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKK 101 K + E + + ++++ K R+++K +E E+ +E+EE+ +E+EEK R +++K Sbjct: 280 KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEK---IREQEEK 336 Query: 102 KRRRKEEEEEKKKKRRRK 119 RR++E EK++K RR+ Sbjct: 337 MRRQEEMMWEKEEKMRRQ 354 Score = 38.1 bits (87), Expect = 0.002 Identities = 26/121 (21%), Positives = 62/121 (51%), Gaps = 1/121 (0%) Query: 4 KKKKKETEETEETEETEEEEEKEGKRKEKRK-EKRKEKEKKKKTKETEKRKEKEEEEKKR 62 K+K + +E + E+E+ E + ++ KRK E+ K +++ + KE + Sbjct: 220 KEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSA 279 Query: 63 KRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKK 122 K + + ++ E +++EE+ +EEK + K +++ + E+EEK +++ K ++ Sbjct: 280 KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRR 339 Query: 123 K 123 + Sbjct: 340 Q 340 >gi|52426743 cisplatin resistance-associated overexpressed protein [Homo sapiens] Length = 432 Score = 77.4 bits (189), Expect = 3e-15 Identities = 31/122 (25%), Positives = 71/122 (58%), Gaps = 1/122 (0%) Query: 3 KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKR 62 K+K +K TEE + E ++E+++ +R+++R+ +R+E+E+K++ +E E+ KE+ + ++R Sbjct: 231 KEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERR 290 Query: 63 KRKRKKKKEEEEREEEE-EEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTK 121 KR R + + + + K +E R R + ++R R + E+K + R + + Sbjct: 291 KRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDR 350 Query: 122 KK 123 ++ Sbjct: 351 RR 352 Score = 70.5 bits (171), Expect = 3e-13 Identities = 26/123 (21%), Positives = 64/123 (52%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 KK+K++++E E+ E E E E ++ + +E+ KE+ +++E++K+++ + + + + Sbjct: 248 KKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRR 307 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120 + + K+ ER + ++ E + R + + RRR + + K K R K+ Sbjct: 308 CSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKS 367 Query: 121 KKK 123 + + Sbjct: 368 RDR 370 Score = 68.2 bits (165), Expect = 2e-12 Identities = 30/101 (29%), Positives = 56/101 (55%) Query: 22 EEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEE 81 EE KE RK + R E+ KK+K + E+ KE+E E ++R+RKR++++EE E+E + Sbjct: 228 EELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDR 287 Query: 82 EEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKK 122 E ++ R ++ R ++ + + ++RRR + Sbjct: 288 ERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSR 328 Score = 65.9 bits (159), Expect = 8e-12 Identities = 28/124 (22%), Positives = 63/124 (50%), Gaps = 1/124 (0%) Query: 1 KKKKKKKKETEETEETEETEEEE-EKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEE 59 +++K++++E EE E EEEE EKE R +R+++ + + + + + + Sbjct: 256 EREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHK 315 Query: 60 KKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRK 119 + R R+R++ + + R + E K + RR K + ++ K + + +++ RK Sbjct: 316 RSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRK 375 Query: 120 TKKK 123 +K+K Sbjct: 376 SKEK 379 Score = 52.8 bits (125), Expect = 7e-08 Identities = 22/131 (16%), Positives = 63/131 (48%), Gaps = 9/131 (6%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEK---------EKKKKTKETEK 51 K+ + + + + T + + + K + +E+R+ + +++ E+K +++ ++ Sbjct: 291 KRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDR 350 Query: 52 RKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEE 111 R+ K + K K + K + E++R+ +E+E+ +++ + R+K+ + E +E Sbjct: 351 RRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKES 410 Query: 112 KKKKRRRKTKK 122 K T + Sbjct: 411 DTKNEVNGTSE 421 Score = 45.4 bits (106), Expect = 1e-05 Identities = 19/112 (16%), Positives = 47/112 (41%) Query: 3 KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKR 62 K+ + +E + + +RK + + + + + K + K + R + + E+ R Sbjct: 315 KRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDR 374 Query: 63 KRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKK 114 K K K+K+ ++++ + EK+ E+ + K E+ K + Sbjct: 375 KSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTSEDIKSE 426 Score = 40.0 bits (92), Expect = 4e-04 Identities = 17/85 (20%), Positives = 40/85 (47%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 + + +++ ++ + + + + ++E RK K KEKR +KK K + K+ E+ Sbjct: 346 RSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNT 405 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEE 85 + K K + E+ + E + + Sbjct: 406 ESKESDTKNEVNGTSEDIKSEGDTQ 430 Score = 33.9 bits (76), Expect = 0.032 Identities = 18/91 (19%), Positives = 40/91 (43%), Gaps = 4/91 (4%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKK----KKTKETEKRKEKE 56 ++K + + ++ + + + + R ++ K KEKEK+ KK+ +EK+ Sbjct: 340 ERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQ 399 Query: 57 EEEKKRKRKRKKKKEEEEREEEEEEEEEEKE 87 E+ + K K E E+ + E + + Sbjct: 400 SEDTNTESKESDTKNEVNGTSEDIKSEGDTQ 430 >gi|19923485 cisplatin resistance-associated overexpressed protein [Homo sapiens] Length = 432 Score = 77.4 bits (189), Expect = 3e-15 Identities = 31/122 (25%), Positives = 71/122 (58%), Gaps = 1/122 (0%) Query: 3 KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKR 62 K+K +K TEE + E ++E+++ +R+++R+ +R+E+E+K++ +E E+ KE+ + ++R Sbjct: 231 KEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERR 290 Query: 63 KRKRKKKKEEEEREEEE-EEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTK 121 KR R + + + + K +E R R + ++R R + E+K + R + + Sbjct: 291 KRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDR 350 Query: 122 KK 123 ++ Sbjct: 351 RR 352 Score = 70.5 bits (171), Expect = 3e-13 Identities = 26/123 (21%), Positives = 64/123 (52%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 KK+K++++E E+ E E E E ++ + +E+ KE+ +++E++K+++ + + + + Sbjct: 248 KKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRR 307 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120 + + K+ ER + ++ E + R + + RRR + + K K R K+ Sbjct: 308 CSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKS 367 Query: 121 KKK 123 + + Sbjct: 368 RDR 370 Score = 68.2 bits (165), Expect = 2e-12 Identities = 30/101 (29%), Positives = 56/101 (55%) Query: 22 EEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEE 81 EE KE RK + R E+ KK+K + E+ KE+E E ++R+RKR++++EE E+E + Sbjct: 228 EELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDR 287 Query: 82 EEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKK 122 E ++ R ++ R ++ + + ++RRR + Sbjct: 288 ERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSR 328 Score = 65.9 bits (159), Expect = 8e-12 Identities = 28/124 (22%), Positives = 63/124 (50%), Gaps = 1/124 (0%) Query: 1 KKKKKKKKETEETEETEETEEEE-EKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEE 59 +++K++++E EE E EEEE EKE R +R+++ + + + + + + Sbjct: 256 EREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHK 315 Query: 60 KKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRK 119 + R R+R++ + + R + E K + RR K + ++ K + + +++ RK Sbjct: 316 RSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRK 375 Query: 120 TKKK 123 +K+K Sbjct: 376 SKEK 379 Score = 52.8 bits (125), Expect = 7e-08 Identities = 22/131 (16%), Positives = 63/131 (48%), Gaps = 9/131 (6%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEK---------EKKKKTKETEK 51 K+ + + + + T + + + K + +E+R+ + +++ E+K +++ ++ Sbjct: 291 KRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDR 350 Query: 52 RKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEE 111 R+ K + K K + K + E++R+ +E+E+ +++ + R+K+ + E +E Sbjct: 351 RRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKES 410 Query: 112 KKKKRRRKTKK 122 K T + Sbjct: 411 DTKNEVNGTSE 421 Score = 45.4 bits (106), Expect = 1e-05 Identities = 19/112 (16%), Positives = 47/112 (41%) Query: 3 KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKR 62 K+ + +E + + +RK + + + + + K + K + R + + E+ R Sbjct: 315 KRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDR 374 Query: 63 KRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKK 114 K K K+K+ ++++ + EK+ E+ + K E+ K + Sbjct: 375 KSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTSEDIKSE 426 Score = 40.0 bits (92), Expect = 4e-04 Identities = 17/85 (20%), Positives = 40/85 (47%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 + + +++ ++ + + + + ++E RK K KEKR +KK K + K+ E+ Sbjct: 346 RSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNT 405 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEE 85 + K K + E+ + E + + Sbjct: 406 ESKESDTKNEVNGTSEDIKSEGDTQ 430 Score = 33.9 bits (76), Expect = 0.032 Identities = 18/91 (19%), Positives = 40/91 (43%), Gaps = 4/91 (4%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKK----KKTKETEKRKEKE 56 ++K + + ++ + + + + R ++ K KEKEK+ KK+ +EK+ Sbjct: 340 ERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQ 399 Query: 57 EEEKKRKRKRKKKKEEEEREEEEEEEEEEKE 87 E+ + K K E E+ + E + + Sbjct: 400 SEDTNTESKESDTKNEVNGTSEDIKSEGDTQ 430 >gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] Length = 2817 Score = 77.4 bits (189), Expect = 3e-15 Identities = 38/136 (27%), Positives = 93/136 (68%), Gaps = 13/136 (9%) Query: 1 KKKKKKKKETEE------TEETEETEEE----EEKEGKRKEKRKEKRKEKEKKKKTKETE 50 K+++++++ EE E+ + +E+ E++ + + +E+ KE+E++K+ ++ + Sbjct: 464 KRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQ 523 Query: 51 KRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEE 110 +++ ++E EK R+R+++K+KE E+ +E++ E E+E+++E+++E R+K+K+K +K +E+ Sbjct: 524 EQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQ 583 Query: 111 EKK---KKRRRKTKKK 123 EK+ +K R K ++K Sbjct: 584 EKECELEKEREKLEEK 599 Score = 77.0 bits (188), Expect = 3e-15 Identities = 36/130 (27%), Positives = 85/130 (65%), Gaps = 9/130 (6%) Query: 3 KKKKKKETEETEETEETEEEEEKEGKRKEKRK-----EKRKEKEKK----KKTKETEKRK 53 K+++++++E + E + E+E +R E+++ EK K ++K +K E+ + Sbjct: 446 KQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIR 505 Query: 54 EKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKK 113 E+E E+++ + K +K++E+ERE+E E++ E ++E+EKE + ++K+++ ++ ++E++K Sbjct: 506 EREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEK 565 Query: 114 KKRRRKTKKK 123 + R+K K+K Sbjct: 566 ELERQKEKEK 575 Score = 77.0 bits (188), Expect = 3e-15 Identities = 36/110 (32%), Positives = 75/110 (68%), Gaps = 1/110 (0%) Query: 5 KKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKR 64 +K+ EE E E +E E ++ KE+ +E+ KE+EK ++ ++ EK KE E+E++K++ Sbjct: 496 EKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRE-RQQEKEKELEKEQEKQRE 554 Query: 65 KRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKK 114 K++K+E+E+E E ++E+E++ ++ KE+ + + +K+R + EE+ E ++ Sbjct: 555 MEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPRE 604 Score = 75.5 bits (184), Expect = 1e-14 Identities = 35/112 (31%), Positives = 77/112 (68%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 +++++K++E E+ E E+ +E E++ K +E+++EK KE EK+++ + +++ K+E+EK Sbjct: 506 EREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEK 565 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEK 112 + +R+++K+KE ++ +E+E+E E EKE E+ EE ++ E++E + Sbjct: 566 ELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESE 617 Score = 75.5 bits (184), Expect = 1e-14 Identities = 39/115 (33%), Positives = 76/115 (66%), Gaps = 1/115 (0%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 +K+++++KE E+ +E E +E E+ +++EK KE KE+EK+++ E E+++EKE+E + Sbjct: 510 EKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQRE-MEKERKQEKEKELE 568 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKK 115 ++K K K+ ++ +E+E+E E E+E ++ EEK E R + ++E E K+ Sbjct: 569 RQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKE 623 Score = 74.7 bits (182), Expect = 2e-14 Identities = 38/120 (31%), Positives = 77/120 (64%), Gaps = 1/120 (0%) Query: 4 KKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRK 63 +++++E E E E +E+E++ K +EK +E+++EKEK+ + KE EK++E E+E K+ K Sbjct: 505 REREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELE-KEQEKQREMEKERKQEK 563 Query: 64 RKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123 K ++++E+E+E ++ +E+E++ E EKE + +K + R E +K++ K+ Sbjct: 564 EKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKE 623 Score = 72.4 bits (176), Expect = 8e-14 Identities = 32/109 (29%), Positives = 74/109 (67%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61 +K+ +E E E +E E E+E E +++++R+++R++ ++++ KE E KE+E++ + Sbjct: 496 EKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREM 555 Query: 62 RKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEE 110 K ++++K++E ER++E+E+E ++ +E+EKE ++++K + E E Sbjct: 556 EKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPRE 604 Score = 71.6 bits (174), Expect = 1e-13 Identities = 32/119 (26%), Positives = 79/119 (66%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 K+ +K E+ EE E E ++ + +EK EK +E+E++K+ ++ +R++++E+E Sbjct: 486 KRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKEL 545 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRK 119 +++++++++ E+E ++E+E+E E +KE+E++ + + ++K+ KE E+ ++K R+ Sbjct: 546 EKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPRE 604 Score = 70.9 bits (172), Expect = 2e-13 Identities = 34/121 (28%), Positives = 77/121 (63%), Gaps = 1/121 (0%) Query: 4 KKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKT-KETEKRKEKEEEEKKR 62 +K K+ E+ E+ EE + +EK +E+ KE EK+++ +E E+ K++E +++K Sbjct: 483 EKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKE 542 Query: 63 KRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKK 122 K K+++++ E E+E ++E+E++ E +KE+ + +K K++ ++ E E++++K K + Sbjct: 543 KELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEP 602 Query: 123 K 123 + Sbjct: 603 R 603 Score = 63.5 bits (153), Expect = 4e-11 Identities = 36/123 (29%), Positives = 77/123 (62%), Gaps = 5/123 (4%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 +++++++KE E+ E ++ +E+E ++ + K++ EK +++EK+ KE E++KEKE+E Sbjct: 522 EQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKE---KELERQKEKEKE-- 576 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120 +K K ++K+ E E+E E+ EE+ E E E +++ + KEEE ++ ++ Sbjct: 577 LQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRS 636 Query: 121 KKK 123 +K+ Sbjct: 637 EKE 639 Score = 63.2 bits (152), Expect = 5e-11 Identities = 34/124 (27%), Positives = 74/124 (59%), Gaps = 1/124 (0%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 K++ + E + +++E E RK + +E+R+ +E++K + ++ E+ Sbjct: 435 KQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGI 494 Query: 61 KRKRKRKKKKEEEEREEEEEEEEE-EKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRK 119 K+ ++ E ERE+E E E+E EKE+E++ E R K +++++ KE+E EK+++++R+ Sbjct: 495 LEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQRE 554 Query: 120 TKKK 123 +K+ Sbjct: 555 MEKE 558 Score = 60.8 bits (146), Expect = 2e-10 Identities = 38/121 (31%), Positives = 67/121 (55%), Gaps = 4/121 (3%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKE---KKKKTKETEKRKEKEE 57 +++++K+KE E+ +E + E+E K+ K KE ++K KEKE K++ KE E KE+E+ Sbjct: 536 ERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREK 595 Query: 58 -EEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKR 116 EEK R+ + E++E E +EE+ +++ R +K+ E E E + Sbjct: 596 LEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQP 655 Query: 117 R 117 R Sbjct: 656 R 656 Score = 38.9 bits (89), Expect = 0.001 Identities = 32/127 (25%), Positives = 68/127 (53%), Gaps = 6/127 (4%) Query: 1 KKKKKKKKETEETEETE-ETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEE 59 +++K+K+KE ++ +E E E E E+E+E K +EK + + E + +E+E KEEE Sbjct: 568 ERQKEKEKELQKMKEQEKECELEKERE-KLEEKIEPREPNLEPMVEKQESENSCNKEEEP 626 Query: 60 K-KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKK---RRRKEEEEEKKKK 115 R+ + +KE E E E + G ++ +K R ++++E+ K+++ Sbjct: 627 VFTRQDSNRSEKEATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQ 686 Query: 116 RRRKTKK 122 +++ ++ Sbjct: 687 WQQQQQQ 693 Score = 38.9 bits (89), Expect = 0.001 Identities = 27/103 (26%), Positives = 50/103 (48%), Gaps = 6/103 (5%) Query: 11 EETEETEETEEEEEKEG-KRKEKRKEKRKEKEKKKKTK-----ETEKRKEKEEEEKKRKR 64 + E E EE+ +KEG R + + K + K +T+ + +R+E + +R Sbjct: 955 DSKEPIERPEEKPKKEGFIRSSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSG 1014 Query: 65 KRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKE 107 KK + +EE E+ +E+E E+ EK + K +K +K+ Sbjct: 1015 PIKKPVLRDMKEEREQRKEKEGEKAEKVTEKVVVKPEKTEKKD 1057 Score = 36.6 bits (83), Expect = 0.005 Identities = 25/96 (26%), Positives = 45/96 (46%), Gaps = 7/96 (7%) Query: 35 EKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEG 94 E+ +EK KK+ + + + E+ K + R + R EE + + K+ Sbjct: 961 ERPEEKPKKEGFIRSSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPV 1020 Query: 95 RRRKKKKKRRRKEEEEEKKKK-------RRRKTKKK 123 R K+++ +RKE+E EK +K + KT+KK Sbjct: 1021 LRDMKEEREQRKEKEGEKAEKVTEKVVVKPEKTEKK 1056 Score = 35.0 bits (79), Expect = 0.014 Identities = 26/121 (21%), Positives = 46/121 (38%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61 +K+ + T++ +E E + R KE ++ + K ++ + E K Sbjct: 921 RKRSVSHGSNHTQKPDEQRSEPSAGIPKVTSRCIDSKEPIERPEEKPKKEGFIRSSEGPK 980 Query: 62 RKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTK 121 ++ K K E EE + KK R KEE E++K+K K + Sbjct: 981 PEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLRDMKEEREQRKEKEGEKAE 1040 Query: 122 K 122 K Sbjct: 1041 K 1041 Score = 32.0 bits (71), Expect = 0.12 Identities = 20/94 (21%), Positives = 49/94 (52%), Gaps = 2/94 (2%) Query: 2 KKKKKKKETEETEETEETEE--EEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEE 59 ++K KK+ + E + E+ + + E + + R+E+ + + + K+ + Sbjct: 964 EEKPKKEGFIRSSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLRD 1023 Query: 60 KKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEE 93 K +R+++K+KE E+ E+ E+ + E+ EK++ Sbjct: 1024 MKEEREQRKEKEGEKAEKVTEKVVVKPEKTEKKD 1057 Score = 29.6 bits (65), Expect = 0.60 Identities = 18/78 (23%), Positives = 37/78 (47%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 K +K K ++E + E+ R +R K+ + +E E+RKEKE E+ Sbjct: 980 KPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLRDMKEEREQRKEKEGEKA 1039 Query: 61 KRKRKRKKKKEEEEREEE 78 ++ ++ K E+ +++ Sbjct: 1040 EKVTEKVVVKPEKTEKKD 1057 Score = 29.6 bits (65), Expect = 0.60 Identities = 13/51 (25%), Positives = 28/51 (54%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEK 51 K+++++ ET+ E E+ +++ K K ++E+R E +K K + K Sbjct: 1256 KRRRQRGSETDTDSEIHESASDKDSLSKGKLPKREERPENKKPVKPHSSFK 1306 Score = 28.1 bits (61), Expect = 1.8 Identities = 14/64 (21%), Positives = 34/64 (53%), Gaps = 3/64 (4%) Query: 44 KKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKR 103 ++ +E+E R E + E KR+R++ E + + E E +++ +G+ K++++ Sbjct: 1237 RQREESETRSESSDFEVVPKRRRQR---GSETDTDSEIHESASDKDSLSKGKLPKREERP 1293 Query: 104 RRKE 107 K+ Sbjct: 1294 ENKK 1297 Score = 27.7 bits (60), Expect = 2.3 Identities = 11/38 (28%), Positives = 25/38 (65%) Query: 63 KRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKK 100 K+++K+ ++EE R++EE+ + ++ E+GR + K Sbjct: 1687 KKQQKRLQDEERRKKEEQVIQVWNKKNANEKGRSQTSK 1724 >gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 828 Score = 77.0 bits (188), Expect = 3e-15 Identities = 40/135 (29%), Positives = 90/135 (66%), Gaps = 12/135 (8%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETE------KRKE 54 +++KK ++ E+ E ++T+E+E+K ++EK +E+ + +E++KK +E E + K Sbjct: 524 REQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKM 583 Query: 55 KEEEEKKRKRKRKKKKEEEEREEEEEE--EEEEKEEEEKEEGRRRKKK----KKRRRKEE 108 +E+EEK R+++ K ++EE+ +E+EE+ E+EEK E++EE + ++++ ++ + +E Sbjct: 584 QEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQE 643 Query: 109 EEEKKKKRRRKTKKK 123 +EEK ++ K +++ Sbjct: 644 QEEKMWEQEEKMREQ 658 Score = 76.3 bits (186), Expect = 6e-15 Identities = 39/136 (28%), Positives = 88/136 (64%), Gaps = 15/136 (11%) Query: 1 KKKKKKKKETEET--EETEETEEEEEKEGKRKEK--RKEKRKEKEKKKKTKETEKRKEKE 56 ++++KK +E EE E+ E+ +E+EEK +++EK +E++ +++++K ++ EK E+E Sbjct: 563 REREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE 622 Query: 57 EEEKKRKRKRKKKKEEEEREEEE-----------EEEEEEKEEEEKEEGRRRKKKKKRRR 105 EE+K ++++ ++EE+ +E+E E+EE+ +E+EEK +G+ K +++ + Sbjct: 623 EEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEK 682 Query: 106 KEEEEEKKKKRRRKTK 121 + +EEK +++ K + Sbjct: 683 MQGQEEKMREQEEKMR 698 Score = 73.6 bits (179), Expect = 4e-14 Identities = 36/122 (29%), Positives = 79/122 (64%), Gaps = 2/122 (1%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61 ++++ ++ E E EE E++K +++EK +E++K +E++KKT + E++ +EE ++ Sbjct: 505 QEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMRE 564 Query: 62 RKRKRKKKKEEEEREEEEEEEEEEK--EEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRK 119 R++K ++++E +EE+ +E+EEK E+EEK + K +++ + E+EEK ++ + Sbjct: 565 REKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEE 624 Query: 120 TK 121 K Sbjct: 625 DK 626 Score = 73.2 bits (178), Expect = 5e-14 Identities = 35/127 (27%), Positives = 86/127 (67%), Gaps = 5/127 (3%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKE---- 56 +++K + +E + ++ E E++E+ +++E+ +E++K ++++K +E +K +E+E Sbjct: 491 QEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTW 550 Query: 57 -EEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKK 115 +EEK R+ +R +++E++ REEEE E+E++ +E+EE R +++K ++E+ +E+++K Sbjct: 551 DQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEK 610 Query: 116 RRRKTKK 122 + +K Sbjct: 611 MWEQEEK 617 Score = 72.8 bits (177), Expect = 6e-14 Identities = 37/119 (31%), Positives = 79/119 (66%), Gaps = 3/119 (2%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEK--EKKKKTKETEKRKEKEEE 58 +++KK +++ E+ +E EE E+E++ + +E++ +++E+ E++K+ +E E++ +EE Sbjct: 300 REQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEE 359 Query: 59 EKKRKRKRKKKKEEEEREEEEEEEEEEK-EEEEKEEGRRRKKKKKRRRKEEEEEKKKKR 116 + +R ++KEE RE+E+ E+EEK +EEE+ R +K +++ E+EEK +K+ Sbjct: 360 RMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQ 418 Score = 71.6 bits (174), Expect = 1e-13 Identities = 33/117 (28%), Positives = 74/117 (63%) Query: 3 KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKR 62 +++K +E E E E+ EEE+ + +E++ ++++EK ++++ K E+ ++ +E+E+K Sbjct: 552 QEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKM 611 Query: 63 KRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRK 119 + +K E+EE ++ +E+EE E+EEK + + K ++ + E+EEK +++ K Sbjct: 612 WEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEK 668 Score = 70.9 bits (172), Expect = 2e-13 Identities = 35/123 (28%), Positives = 85/123 (69%), Gaps = 1/123 (0%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 + ++++KK EE E E EE+ +++ ++ +++EK E+E+K + +E EK E+EE+ Sbjct: 561 RMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQE-EKMWEQEEKMW 619 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120 +++ + K +++EE E+EE+ +E++E+ ++E + R++++K R +EE+ + ++++ R+ Sbjct: 620 EQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQ 679 Query: 121 KKK 123 ++K Sbjct: 680 EEK 682 Score = 70.5 bits (171), Expect = 3e-13 Identities = 41/131 (31%), Positives = 86/131 (65%), Gaps = 9/131 (6%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKET---EKRKEKEE 57 K+ ++++KE E ++ E EE+ +++ ++ +++EK +E+E+K +E E+ K+ E Sbjct: 290 KELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMRE 349 Query: 58 EEKKRKRKRKKKKEEEER--EEEEEEEEEEK--EEEEK--EEGRRRKKKKKRRRKEEEEE 111 +E+K + + ++ E++ER E+EE E+EK E+EEK EE R R+++KK R +EE Sbjct: 350 QEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMR 409 Query: 112 KKKKRRRKTKK 122 +++++ +K ++ Sbjct: 410 EQEEKMQKQEE 420 Score = 70.5 bits (171), Expect = 3e-13 Identities = 36/125 (28%), Positives = 85/125 (68%), Gaps = 3/125 (2%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEK---RKEKRKEKEKKKKTKETEKRKEKEE 57 +++K +++E + E+ E+ E+EEK +++EK ++EK E+E++ K +E E+ ++E Sbjct: 579 QEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQE 638 Query: 58 EEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRR 117 E+ + + ++ ++EE+ RE+EE+ E+E++ + +EE R +++K + ++E+ E+++K R Sbjct: 639 EKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMR 698 Query: 118 RKTKK 122 + +K Sbjct: 699 GQEEK 703 Score = 69.7 bits (169), Expect = 5e-13 Identities = 34/126 (26%), Positives = 84/126 (66%), Gaps = 3/126 (2%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEK--EKKKKTKETEKRKEKEEE 58 ++++K+ +E E+ +E E E+K+ + +E++ ++++EK E+++K +E E++ ++EE Sbjct: 279 RRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEE 338 Query: 59 EKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKK-KRRRKEEEEEKKKKRR 117 + K+ +++E++ R++EE E+++ EKEE R ++K ++ K +EEE+ ++R Sbjct: 339 RLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIRERE 398 Query: 118 RKTKKK 123 +K +++ Sbjct: 399 KKMREE 404 Score = 68.9 bits (167), Expect = 9e-13 Identities = 40/151 (26%), Positives = 89/151 (58%), Gaps = 28/151 (18%) Query: 1 KKKKKKKKETEET--EETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEE- 57 ++++KK +E EET E+ E+ +++EE +++EK ++++ E+K+K E EK +E+EE Sbjct: 395 REREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEK 454 Query: 58 ----------------EEKKRKRKRKKKKEEEEREEEEEE---------EEEEKEEEEKE 92 +EKK R+ K +++E++ E+EE+ ++EE+ E+ E Sbjct: 455 IWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDE 514 Query: 93 EGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123 R ++++ + ++K ++E+K + +KT+++ Sbjct: 515 RLREKEERMREQKKMWQQEEKMREEKKTQEQ 545 Score = 68.6 bits (166), Expect = 1e-12 Identities = 37/123 (30%), Positives = 83/123 (67%), Gaps = 8/123 (6%) Query: 7 KKETEETEETEETEEEEEKEGKRKEKRKE---KRKEKEKKKKTKETEKRKEKEE--EEKK 61 ++E E E+ ++ ++EEK +++E+ +E K +E+E+K + +E R++++E E++K Sbjct: 238 RQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEK 297 Query: 62 RKRKRKKKKEEEEREEEEEE---EEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRR 118 R++KK +E+EE+ +E+EE E+EEK E++E+ R++++ + K+ E+++K R + Sbjct: 298 ELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQ 357 Query: 119 KTK 121 + + Sbjct: 358 EER 360 Score = 68.6 bits (166), Expect = 1e-12 Identities = 37/129 (28%), Positives = 85/129 (65%), Gaps = 6/129 (4%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKR-KEKRKE-KEKKKKTKETEKRKEKEEE 58 K+++K ++ E E E E+E++ +R+EKR +E+ KE +E++K+ +E +K +E+EE+ Sbjct: 252 KQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQ 311 Query: 59 ----EKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKK 114 E+K + +K +E+EE+ +EE E+E++ +E+ ++ + +++R +++E ++K Sbjct: 312 MQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREK 371 Query: 115 KRRRKTKKK 123 + R + ++K Sbjct: 372 EERMREQEK 380 Score = 68.6 bits (166), Expect = 1e-12 Identities = 37/128 (28%), Positives = 83/128 (64%), Gaps = 7/128 (5%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEK----RKEKEKKKKTKETEKRKEKE 56 ++K+++ +E E+ E EE +EEE+ +R++K +E+ R+++EK +K +E +E++ Sbjct: 369 REKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEK 428 Query: 57 EEEKKRKRKRKKKKEEEEREEEEEE---EEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKK 113 E +++R ++K+K E+E+ +E+EE E+EEK +++E + KK ++ + E+E++ Sbjct: 429 EWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQM 488 Query: 114 KKRRRKTK 121 ++ K + Sbjct: 489 WEQEEKMR 496 Score = 68.6 bits (166), Expect = 1e-12 Identities = 37/129 (28%), Positives = 80/129 (62%), Gaps = 6/129 (4%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEK-RKEKRKEKE-----KKKKTKETEKRKE 54 +++K +++E + E+ E+ ++EE G+ K+ R+EK +E+E +++K ++ E++ Sbjct: 444 EQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMW 503 Query: 55 KEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKK 114 +EE + +R ++KEE RE+++ ++EEK EEK+ + KK + K EEE+ + Sbjct: 504 DQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMR 563 Query: 115 KRRRKTKKK 123 +R +K +++ Sbjct: 564 EREKKMREE 572 Score = 67.8 bits (164), Expect = 2e-12 Identities = 36/128 (28%), Positives = 80/128 (62%), Gaps = 9/128 (7%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEK------RKEKRKEKEKKKKTKETEKRKE 54 K ++++K+ E+ +E E E+E ++ K +E+ ++EK E+E+K + +E + ++ Sbjct: 277 KMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQ 336 Query: 55 KE---EEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEE 111 +E E+EK+ + + +K +++EER E++E EKEE +E+ + ++++K + +E E Sbjct: 337 EERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIRE 396 Query: 112 KKKKRRRK 119 ++KK R + Sbjct: 397 REKKMREE 404 Score = 67.4 bits (163), Expect = 3e-12 Identities = 40/141 (28%), Positives = 89/141 (63%), Gaps = 18/141 (12%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEK--RKEKRKEKEKKKKTKETEKRKEKEE- 57 ++KK +++E + E+ E+ E+EEK +++EK R+E+R +++K+ ++ +K +++EE Sbjct: 301 EQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEER 360 Query: 58 ---------EEKKRKRKRKK------KKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKK 102 E+++R R+++K K +EEER E E++ E+EE +E+ + +K+++ Sbjct: 361 MWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEE 420 Query: 103 RRRKEEEEEKKKKRRRKTKKK 123 ++EE+E +++R + K+K Sbjct: 421 NMWEQEEKEWQQQRLPEQKEK 441 Score = 67.0 bits (162), Expect = 3e-12 Identities = 32/127 (25%), Positives = 86/127 (67%), Gaps = 4/127 (3%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 +++K +++E E+ +E E+E++ ++K+ R+++ + +E+++K E E++ ++EE+ Sbjct: 274 QEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKM 333 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRR----KEEEEEKKKKR 116 R+ +R ++E++ RE+E++ ++E+ E++E R K+++ R + ++EE+ ++++R Sbjct: 334 WRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEER 393 Query: 117 RRKTKKK 123 R+ +KK Sbjct: 394 IREREKK 400 Score = 66.2 bits (160), Expect = 6e-12 Identities = 34/121 (28%), Positives = 82/121 (67%), Gaps = 6/121 (4%) Query: 9 ETEETEETEETEEEEEKEGKRKEK---RKEKRKEKEKKKKTKETEKRKEKE---EEEKKR 62 + E + EE E+E+K K++EK ++E+ +E+E K + +E + R++++ E+EK+ Sbjct: 233 QEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKEL 292 Query: 63 KRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKK 122 + + K+ +E+++ E+EE+ +E++E+ ++E + R++++K R+EE +++K+ R+ ++ Sbjct: 293 REQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQ 352 Query: 123 K 123 K Sbjct: 353 K 353 Score = 66.2 bits (160), Expect = 6e-12 Identities = 28/121 (23%), Positives = 81/121 (66%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 ++K+ +++E + ++ E E++E+ +++E+ +E+ K E+++K +E E+ +E+E++ + Sbjct: 343 QEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMR 402 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120 + + ++++E+ +++EE E+EEKE +++ +++K ++ + +E+EEK ++ K Sbjct: 403 EEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKI 462 Query: 121 K 121 + Sbjct: 463 R 463 Score = 66.2 bits (160), Expect = 6e-12 Identities = 40/139 (28%), Positives = 84/139 (60%), Gaps = 16/139 (11%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKET---EKRKEKEE 57 ++++K +++ E+ E EE E+E+E K +E+ + +++EK ++ +E ++ K +E+ Sbjct: 599 EQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQ 658 Query: 58 EEKKRKRKRKKKKEEEEREEEEE----EEEEEKEEEEKEEGRRRKK---------KKKRR 104 EEK R+++ K + +EE+ E+EE +EE+ +E+EEK G+ K ++++ Sbjct: 659 EEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKM 718 Query: 105 RKEEEEEKKKKRRRKTKKK 123 +EE +K++R R K+K Sbjct: 719 WGQEEMREKEERIRDQKEK 737 Score = 65.9 bits (159), Expect = 8e-12 Identities = 34/118 (28%), Positives = 77/118 (65%), Gaps = 4/118 (3%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKE----E 57 ++++ ++ E+ E E+ +E+EEK +++EK +++ + ++KK EK +E+E E Sbjct: 431 QQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWE 490 Query: 58 EEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKK 115 +E+K + + +K ++EER E++E EKEE +E+ + ++++K R +++ +E++KK Sbjct: 491 QEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKK 548 Score = 65.5 bits (158), Expect = 1e-11 Identities = 31/121 (25%), Positives = 81/121 (66%), Gaps = 1/121 (0%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61 +++K +++ ++ E EE ++E++ +E+R ++ E+ ++K+ + E++K ++EEK Sbjct: 477 RQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKM 536 Query: 62 RKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTK 121 R+ K+ +++E++ ++EE+ EEE+ E+E+ R +++ R ++E+ +E+++K R + + Sbjct: 537 REEKKTQEQEKKTWDQEEKMREEER-MREREKKMREEEEMMREQEEKMQEQEEKMREQEE 595 Query: 122 K 122 K Sbjct: 596 K 596 Score = 65.1 bits (157), Expect = 1e-11 Identities = 32/121 (26%), Positives = 80/121 (66%), Gaps = 6/121 (4%) Query: 1 KKKKKKKKETEET--EETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEE 58 ++++ K +E EE E+ E+ +E+EEK +++EK +E+ ++ ++++ + ++ K +E+E Sbjct: 621 QEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQE 680 Query: 59 EKKRKRKRKKKKEEEEREEEEE----EEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKK 114 EK + ++ K +++EE+ +EE +EE+ +EEK G+ ++K+ R ++++E+ ++ Sbjct: 681 EKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQE 740 Query: 115 K 115 + Sbjct: 741 R 741 Score = 65.1 bits (157), Expect = 1e-11 Identities = 39/115 (33%), Positives = 73/115 (63%), Gaps = 6/115 (5%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEK---RKEKRKEKEKKKKTKETEKRKEKEE 57 +++K +++E + E+ E+ E+EEK +++EK ++EK +E+E+K + +E K +E+ Sbjct: 637 QEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQE---EKMREQ 693 Query: 58 EEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEK 112 EEK R ++ K +EE+ +EE+ ++E EKEE R +K+K + R E EE+ Sbjct: 694 EEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEER 748 Score = 64.7 bits (156), Expect = 2e-11 Identities = 38/129 (29%), Positives = 84/129 (65%), Gaps = 6/129 (4%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEK--RKEKR-KEKEKKKKTKETEKRKEKEE 57 ++KK +K+E + + E E+E K +++EK R+EKR +E+EK+ + +E E R++K+ Sbjct: 246 QEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKL 305 Query: 58 EEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEK---EEGRRRKKKKKRRRKEEEEEKKK 114 E++ + + +++K E+ E+ E+EE+ +EE+ +E + R++++K R +EE ++ Sbjct: 306 REQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQD 365 Query: 115 KRRRKTKKK 123 +R R+ +++ Sbjct: 366 ERLREKEER 374 Score = 64.7 bits (156), Expect = 2e-11 Identities = 40/127 (31%), Positives = 85/127 (66%), Gaps = 10/127 (7%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEK--EKKKKTKETEKRKEKEE- 57 ++++K ++ E E E+ E+E++ + +E+R ++ E+ EK+++ +E EK E+EE Sbjct: 328 EQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEK 387 Query: 58 -EEKKRKRKRKKKKEEEE---REEEEEEEEEEK---EEEEKEEGRRRKKKKKRRRKEEEE 110 +E++R R+R+KK EEE RE+EE+ +++E+ E+EEKE ++R ++K + E+E+ Sbjct: 388 MQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEK 447 Query: 111 EKKKKRR 117 ++++ + Sbjct: 448 MQEQEEK 454 Score = 64.3 bits (155), Expect = 2e-11 Identities = 33/128 (25%), Positives = 81/128 (63%), Gaps = 6/128 (4%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61 ++++ ++ E E EE E+EK +++EK +E+ + +E++KK +E E+ ++EE+ + Sbjct: 357 QEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQ 416 Query: 62 RKRKRKKKKEEEEREEEEEEEEEEK--EEEEKEEGRRRKKKKKRRRKEEEE----EKKKK 115 ++ + ++EE+E +++ E++EK E+E+ +E + +++ + +++EE EKK Sbjct: 417 KQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMW 476 Query: 116 RRRKTKKK 123 R+ K +++ Sbjct: 477 RQEKMREQ 484 Score = 63.5 bits (153), Expect = 4e-11 Identities = 37/119 (31%), Positives = 70/119 (58%), Gaps = 1/119 (0%) Query: 4 KKKKKETEETEETEETEEEEEKEGKRKEKRK-EKRKEKEKKKKTKETEKRKEKEEEEKKR 62 KKK E +E E+E+ E + ++ KRK E+ K + +T ++ ++EEE + Sbjct: 186 KKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELRE 245 Query: 63 KRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTK 121 + K+ +K+EE+ +EE E+E + E+EE RR++K+ R +++E E++K+ R + K Sbjct: 246 QEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKK 304 Score = 62.8 bits (151), Expect = 6e-11 Identities = 37/125 (29%), Positives = 82/125 (65%), Gaps = 13/125 (10%) Query: 1 KKKKKKKKETEETEETEETEEEEEK----EGKRKEKRKEKRKEKEKKKKTKETEKRKEKE 56 +++K +++E + E+ E+ +E+EEK E K E+ +E + +++++ ++ EK +E+E Sbjct: 586 QEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQE 645 Query: 57 E-----EEKKRKRKRKKKKEEEEREEEEEE-EEEEKEEEEKEEGRRRKKKKKRRRKEE-- 108 E EEK R+++ K +++EE+ + +EE+ E+E++ + +EE R +++K R ++E+ Sbjct: 646 EKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMW 705 Query: 109 -EEEK 112 +EEK Sbjct: 706 GQEEK 710 Score = 62.8 bits (151), Expect = 6e-11 Identities = 35/129 (27%), Positives = 79/129 (61%), Gaps = 8/129 (6%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKE----E 57 ++++K E EE ++ +E EE ++ ++ ++++EK E+E+K + +E + R+++E + Sbjct: 613 EQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQ 672 Query: 58 EEKKRKRKRKKKKEEEEREEEEE----EEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKK 113 EEK R+++ K + +EE+ E+EE +EE+ +EEK G+ K + +E+EE + Sbjct: 673 EEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIR 732 Query: 114 KKRRRKTKK 122 ++ + ++ Sbjct: 733 DQKEKMQER 741 Score = 57.4 bits (137), Expect = 3e-09 Identities = 29/122 (23%), Positives = 77/122 (63%), Gaps = 1/122 (0%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 K+ K+K + + +T +E+ +++E+ +E+ K+ K+++ ++ + +E+E K Sbjct: 211 KELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGK 270 Query: 61 KRKRKRKKKKEEEE-REEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRK 119 R+++ K +++E+ RE+E+E E+EKE E+++ R ++++ + + ++ E+++K R ++ Sbjct: 271 MREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQE 330 Query: 120 TK 121 K Sbjct: 331 EK 332 Score = 54.3 bits (129), Expect = 2e-08 Identities = 43/137 (31%), Positives = 75/137 (54%), Gaps = 16/137 (11%) Query: 3 KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRK-EKEEEEKK 61 KK + E T+E + E + E+ K+K E ++K + E+EK + + +E K Sbjct: 155 KKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELK 214 Query: 62 RKRKRKK----------KKEEEEREEEEEEEEEEK--EEEEK---EEGRRRKKKKKRRRK 106 RK +R K +EE R+EEE E+E+K ++EEK +E R R+++ K R + Sbjct: 215 RKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQ 274 Query: 107 EEEEEKKKKRRRKTKKK 123 EE+ +++KR R+ +K+ Sbjct: 275 EEKMRRQEKRLREQEKE 291 >gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] Length = 2454 Score = 77.0 bits (188), Expect = 3e-15 Identities = 46/149 (30%), Positives = 81/149 (54%), Gaps = 26/149 (17%) Query: 1 KKKKKKKKETEETEET--------EETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKR 52 K + ++K +E++E++ EE E E+++ R K+ E+ ++ ++ ++R Sbjct: 1329 KGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRR 1388 Query: 53 KEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEE------KEEGRRRKKKKK---- 102 + K +E+ + K ++EEEE+EEEEEEEEEE+EEEE K G+ RKK +K Sbjct: 1389 RIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKD 1448 Query: 103 --------RRRKEEEEEKKKKRRRKTKKK 123 KEEEE +K+ R+ +++ Sbjct: 1449 DKLRTETQNALKEEEERRKRIAERERERE 1477 Score = 65.9 bits (159), Expect = 8e-12 Identities = 31/122 (25%), Positives = 68/122 (55%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 K+ K + + +E++E+++ +E + + +++++ + + K E E+ + +++K Sbjct: 1326 KEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKK 1385 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120 KR+R + ++ E + EEEEEEKEEEE+EE ++++ + K +K+ RK Sbjct: 1386 KRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKI 1445 Query: 121 KK 122 K Sbjct: 1446 LK 1447 Score = 63.5 bits (153), Expect = 4e-11 Identities = 31/129 (24%), Positives = 72/129 (55%), Gaps = 7/129 (5%) Query: 1 KKKKKKKKETEETE-------ETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRK 53 ++KK K KE +E + +E++E+ + +E E+ E E+ + ++ + + + Sbjct: 1316 EEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELE 1375 Query: 54 EKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKK 113 E + K++K++R+ K +E+ E + EEE+EE+E+EE +++++ + ++ + Sbjct: 1376 ENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSP 1435 Query: 114 KKRRRKTKK 122 K R+K +K Sbjct: 1436 GKGRKKIRK 1444 Score = 59.3 bits (142), Expect = 7e-10 Identities = 29/123 (23%), Positives = 64/123 (52%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 K K K+ KE + + + E+ E ++ E+ E E +++ + +K + EE + Sbjct: 1319 KTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQ 1378 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120 + +++KK++ + +E+ E + EEEE+E+ +++++ +EE+E K K Sbjct: 1379 RSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKG 1438 Query: 121 KKK 123 +KK Sbjct: 1439 RKK 1441 Score = 58.9 bits (141), Expect = 9e-10 Identities = 35/130 (26%), Positives = 64/130 (49%), Gaps = 11/130 (8%) Query: 3 KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKET-------EKRKEK 55 KK+ K+ EE EE + + E + +K + + + + K T E++K K Sbjct: 1262 KKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTK 1321 Query: 56 EEEEKKRKRKRKKKKEEEEREEEEEEE----EEEKEEEEKEEGRRRKKKKKRRRKEEEEE 111 +E K+ K + ++K E+ E+ + +E EE E E+++ R R KK + + Sbjct: 1322 PKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSY 1381 Query: 112 KKKKRRRKTK 121 K+KK+RR+ K Sbjct: 1382 KQKKKRRRIK 1391 Score = 58.9 bits (141), Expect = 9e-10 Identities = 31/121 (25%), Positives = 67/121 (55%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 ++ K+KK+ + E++ E + + +E+ KE+ +E+E++++ +E ++ + + K Sbjct: 1378 QRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGK 1437 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120 RK+ RK K+++ R E + +EE+E ++ R R+++K R E E+ K T Sbjct: 1438 GRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIEDASPTKCPITT 1497 Query: 121 K 121 K Sbjct: 1498 K 1498 Score = 52.0 bits (123), Expect = 1e-07 Identities = 35/117 (29%), Positives = 59/117 (50%), Gaps = 10/117 (8%) Query: 3 KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKR 62 + K E EE E+ EE EEEEE+E + +++ + + + +KK ++ K ++K R Sbjct: 1399 ENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILK------DDKLR 1452 Query: 63 KRKRKKKKEEEERE----EEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKK 115 + KEEEER E E E E+ +E E E+ K + +E+E+ K+ Sbjct: 1453 TETQNALKEEEERRKRIAEREREREKLREVIEIEDASPTKCPITTKLVLDEDEETKE 1509 Score = 49.7 bits (117), Expect = 6e-07 Identities = 34/129 (26%), Positives = 60/129 (46%), Gaps = 14/129 (10%) Query: 8 KETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRK 67 K ++E +++E E+ KR K+ E+ E+ K +E + EE +K R R R Sbjct: 1243 KANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRL 1302 Query: 68 KKKEEEEREEEEEEEEEEKEEEEKE-EGRRRKKKKKRRRKE-------------EEEEKK 113 + + + E EE++ K +E KE +GR R+K ++ E E+++ Sbjct: 1303 LRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQ 1362 Query: 114 KKRRRKTKK 122 + R R KK Sbjct: 1363 RPRTRSAKK 1371 Score = 45.1 bits (105), Expect = 1e-05 Identities = 41/131 (31%), Positives = 65/131 (49%), Gaps = 12/131 (9%) Query: 4 KKKKKETEETEETEETEEEEEKEGKRKEKRK---------EKRKEKEKKKKTKETEKRKE 54 K++ + E + ET+E+ K K K +K EK +K++ +T E +K++ Sbjct: 889 KEQSFTSLEVRKVAETKEKS-KHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQS 947 Query: 55 KE-EEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKK 113 K+ EEKK+ KKK + E++ E + EK E +E K K+ + + EKK Sbjct: 948 KKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKK 1007 Query: 114 -KKRRRKTKKK 123 KK R KT KK Sbjct: 1008 SKKIRDKTSKK 1018 Score = 44.3 bits (103), Expect = 2e-05 Identities = 35/145 (24%), Positives = 70/145 (48%), Gaps = 22/145 (15%) Query: 1 KKKKKK-------KKETEETEETEETEEEEEKEGKR-KEKRKEKRKEKEKKKK----TKE 48 K KKK +K T + + + +E+++ K G +EK++ K K +K+ + + Sbjct: 1014 KTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSD 1073 Query: 49 TEKRKEKEE----EEKKRKR----KRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKK 100 TEK KE+ +K+ KR +R+ + +E + EE E+ +++K++ Sbjct: 1074 TEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQR 1133 Query: 101 KKRRRKE--EEEEKKKKRRRKTKKK 123 ++K +E+K+ R TK+K Sbjct: 1134 TSSKKKAVIVKEKKRNSLRTSTKRK 1158 Score = 43.5 bits (101), Expect = 4e-05 Identities = 32/134 (23%), Positives = 64/134 (47%), Gaps = 13/134 (9%) Query: 3 KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEE----- 57 KK + ET E ++ + + EEK+ K+K + E++ + + TEK E+EE Sbjct: 932 KKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFP 991 Query: 58 ---EEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGR-----RRKKKKKRRRKEEE 109 ++ K +KK ++ R++ ++++E + EK G+ + KK + Sbjct: 992 KGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGR 1051 Query: 110 EEKKKKRRRKTKKK 123 E+K+ K K+ +K Sbjct: 1052 EKKRCKLLGKSSRK 1065 Score = 38.5 bits (88), Expect = 0.001 Identities = 24/91 (26%), Positives = 45/91 (49%), Gaps = 3/91 (3%) Query: 5 KKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKR 64 KKK++T+ E+ + E EKE K K R K++ TK+ + ++++ +K Sbjct: 767 KKKRQTQS--ESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDN 824 Query: 65 K-RKKKKEEEEREEEEEEEEEEKEEEEKEEG 94 + K K +E ++ E ++E+E EG Sbjct: 825 QGHKNLKTSQEGSSDDAERKQERETFSSAEG 855 Score = 37.7 bits (86), Expect = 0.002 Identities = 43/179 (24%), Positives = 70/179 (39%), Gaps = 57/179 (31%) Query: 2 KKKKKKKETEETEETEETEEEEEKE-------GKRKEKRKEKRKEKEKKKKTKETEKRKE 54 KKK K E + ++ TE+ E+E G ++ K EK+ KK +T K+K+ Sbjct: 961 KKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKD 1020 Query: 55 K----------------EEEEKK-------RKRKRKKKKEEEEREEEEEEEEEEKEEEEK 91 + E+KK R++KR K + R+ ++ + ++ K Sbjct: 1021 ELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMK 1080 Query: 92 EEGRRRKKKK--------------KRRRKE-------------EEEEKKKKRRRKTKKK 123 E+G K+ KR KE E+ KKKK+R +KKK Sbjct: 1081 EDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKK 1139 Score = 37.0 bits (84), Expect = 0.004 Identities = 24/101 (23%), Positives = 43/101 (42%), Gaps = 1/101 (0%) Query: 3 KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKR 62 K+ K+ E E +E + E+ E KKKK + + K+K +EKKR Sbjct: 1089 KRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKR 1148 Query: 63 KRKR-KKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKK 102 R K+++ + + E+ ++ EG ++K K Sbjct: 1149 NSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIK 1189 Score = 35.4 bits (80), Expect = 0.011 Identities = 16/91 (17%), Positives = 40/91 (43%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61 ++++ T+E + + E ++ +K+K++ KKK EK++ K Sbjct: 1097 RERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTK 1156 Query: 62 RKRKRKKKKEEEEREEEEEEEEEEKEEEEKE 92 RK+ + E++++ E +E++ Sbjct: 1157 RKQADITSSSSSDIEDDDQNSIGEGSSDEQK 1187 Score = 35.0 bits (79), Expect = 0.014 Identities = 21/117 (17%), Positives = 54/117 (46%), Gaps = 9/117 (7%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKR--KEKRKEKEKKKKTKETEKRKEKEEE 58 K K+K+K T ++ + K+GK + +K+++ + + ++E KE + Sbjct: 738 KGKRKRKSSTSGSDF-------DTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSM 790 Query: 59 EKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKK 115 K + KK+ ++ + E+E+ ++ +G + K + ++ E K+++ Sbjct: 791 SKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQER 847 Score = 33.9 bits (76), Expect = 0.032 Identities = 31/127 (24%), Positives = 60/127 (47%), Gaps = 16/127 (12%) Query: 3 KKKKKKET----EETEETEETEEEEEKEGKRKEKRK------EKRKEKEKKKKTKETEKR 52 ++K+++ET E T + + T E +K++ +K KE+ + E K Sbjct: 842 ERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKV 901 Query: 53 KEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEK 112 E +E+ K K K KK ++ + E+ ++++ +E E+ KK+ +K EE+K Sbjct: 902 AETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDD------KKQSKKGTEEKK 955 Query: 113 KKKRRRK 119 K +K Sbjct: 956 KPSDFKK 962 Score = 33.5 bits (75), Expect = 0.042 Identities = 31/118 (26%), Positives = 58/118 (49%), Gaps = 10/118 (8%) Query: 1 KKKKK----KKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKE 56 ++KKK KKK + ++ E + + EK +R+E + K+ K T + EK K K+ Sbjct: 952 EEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEK-KSKK 1010 Query: 57 EEEKKRKRKRKKK--KEEEEREEEEEEEEEEKEEEEKEEGRRRKKKK---KRRRKEEE 109 +K K+K + E+ + + + E+K+ + GR +K+ K K RK ++ Sbjct: 1011 IRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQD 1068 Score = 33.1 bits (74), Expect = 0.054 Identities = 18/86 (20%), Positives = 41/86 (47%) Query: 34 KEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEE 93 K+ + ++++K T ++ +K + K +KK++ + E + E E+E + K Sbjct: 735 KDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIG 794 Query: 94 GRRRKKKKKRRRKEEEEEKKKKRRRK 119 R KK+ K+ + + +K +K Sbjct: 795 AARTTKKRIPNTKDFDSSEDEKHSKK 820 Score = 31.6 bits (70), Expect = 0.16 Identities = 22/99 (22%), Positives = 44/99 (44%), Gaps = 4/99 (4%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 K++ +TE+ E+ +K KR E R+ R+ K+ TKE + + E+ Sbjct: 1065 KRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRE--RRNLSSKRNTKEIQSGSSSSDAEE 1122 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKK 99 + +KKK + +++ +EK+ +RK+ Sbjct: 1123 SSEDNKKKK--QRTSSKKKAVIVKEKKRNSLRTSTKRKQ 1159 Score = 31.6 bits (70), Expect = 0.16 Identities = 16/91 (17%), Positives = 39/91 (42%), Gaps = 2/91 (2%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 ++ K+ T+E + + + EE K+K++R +KK + +KR K Sbjct: 1099 RRNLSSKRNTKEIQSGSSSSDAEESS--EDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTK 1156 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEK 91 +++ + ++++ E +E+K Sbjct: 1157 RKQADITSSSSSDIEDDDQNSIGEGSSDEQK 1187 Score = 31.6 bits (70), Expect = 0.16 Identities = 22/126 (17%), Positives = 52/126 (41%), Gaps = 13/126 (10%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEK-------------EKKKKTKE 48 K+K+ + + + E+ ++ EG E++ + E + +K Sbjct: 1156 KRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKS 1215 Query: 49 TEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEE 108 + ++++ + + KK EE + +E+ ++E EEG++R K+ + Sbjct: 1216 VPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGD 1275 Query: 109 EEEKKK 114 EE K + Sbjct: 1276 EEAKNQ 1281 Score = 30.8 bits (68), Expect = 0.27 Identities = 21/96 (21%), Positives = 40/96 (41%), Gaps = 1/96 (1%) Query: 15 ETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK-RKRKRKKKKEEE 73 E + E + KEK ++ K + K +TK + K E+K K + K +++ Sbjct: 372 EEDLNSEFRAMDAVNKEKNTKEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQV 431 Query: 74 EREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEE 109 + E + E++ K G KK ++ + E Sbjct: 432 DSEHMHQNVPTEEQRTNKSTGGEHKKSDRKEEPQYE 467 Score = 30.8 bits (68), Expect = 0.27 Identities = 22/96 (22%), Positives = 42/96 (43%), Gaps = 4/96 (4%) Query: 20 EEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEE----EKKRKRKRKKKKEEEER 75 EE+ E + + +++ KE K + E + K E+ EKK K + K ++ Sbjct: 372 EEDLNSEFRAMDAVNKEKNTKEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQV 431 Query: 76 EEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEE 111 + E + EE+ + + KK R++E + E Sbjct: 432 DSEHMHQNVPTEEQRTNKSTGGEHKKSDRKEEPQYE 467 Score = 30.0 bits (66), Expect = 0.46 Identities = 19/88 (21%), Positives = 43/88 (48%), Gaps = 5/88 (5%) Query: 6 KKKETEETEETEETEEEEEKEGKRK---EKRKEKRKEKEKKKKTKETEKRKEK--EEEEK 60 K+K T+E + + E + ++G++ EK+ + E + +K ++E + EE++ Sbjct: 387 KEKNTKEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPTEEQR 446 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEE 88 K + K+ + +EE + E E+ Sbjct: 447 TNKSTGGEHKKSDRKEEPQYEPANTSED 474 Score = 29.6 bits (65), Expect = 0.60 Identities = 24/116 (20%), Positives = 45/116 (38%), Gaps = 16/116 (13%) Query: 19 TEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEE 78 T ++++ + + + +K +E K E +E E+ +KR K + E Sbjct: 1219 TVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGK-----QNEENP 1273 Query: 79 EEEEEEEKEEEEKEEGRRRKKKKKRRRK-----------EEEEEKKKKRRRKTKKK 123 +EE + + E + KK + R + E EEKK K + + K Sbjct: 1274 GDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVK 1329 Score = 28.9 bits (63), Expect = 1.0 Identities = 19/87 (21%), Positives = 33/87 (37%), Gaps = 2/87 (2%) Query: 8 KETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRK-- 65 +E+EET + + E K++ T +EK K KRK Sbjct: 27 EESEETSSPPRLAMNQNTDKISGSGSNSDMMENSKEEGTSSSEKSKSSGSSRSKRKPSIV 86 Query: 66 RKKKKEEEEREEEEEEEEEEKEEEEKE 92 K + ++E+ ++E E+ E E Sbjct: 87 TKYVESDDEKPLDDETVNEDASNENSE 113 Score = 28.5 bits (62), Expect = 1.3 Identities = 22/113 (19%), Positives = 50/113 (44%), Gaps = 2/113 (1%) Query: 11 EETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKK 70 +E E E +K+ E R K+++ T +K KE+ + + K Sbjct: 845 QERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVR--KVA 902 Query: 71 EEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123 E +E+ + + + +K ++ + + KK + + E++KK+ ++ +KK Sbjct: 903 ETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKK 955 Score = 26.2 bits (56), Expect = 6.7 Identities = 12/49 (24%), Positives = 24/49 (48%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETE 50 K +K+ ++E + TEE+ + E +K RKE+ + + +E Sbjct: 425 KLSRKQVDSEHMHQNVPTEEQRTNKSTGGEHKKSDRKEEPQYEPANTSE 473 Score = 26.2 bits (56), Expect = 6.7 Identities = 19/119 (15%), Positives = 47/119 (39%), Gaps = 5/119 (4%) Query: 7 KKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKR 66 ++ TE T ++EE + K K+K ++K+K+ + + + K ++ + Sbjct: 627 RRPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSET 686 Query: 67 KKKKEEEER-----EEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120 + + + +E + + E K + + ++ K KR+RK+ Sbjct: 687 VDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKS 745 >gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] Length = 2492 Score = 77.0 bits (188), Expect = 3e-15 Identities = 46/149 (30%), Positives = 81/149 (54%), Gaps = 26/149 (17%) Query: 1 KKKKKKKKETEETEET--------EETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKR 52 K + ++K +E++E++ EE E E+++ R K+ E+ ++ ++ ++R Sbjct: 1367 KGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRR 1426 Query: 53 KEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEE------KEEGRRRKKKKK---- 102 + K +E+ + K ++EEEE+EEEEEEEEEE+EEEE K G+ RKK +K Sbjct: 1427 RIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKD 1486 Query: 103 --------RRRKEEEEEKKKKRRRKTKKK 123 KEEEE +K+ R+ +++ Sbjct: 1487 DKLRTETQNALKEEEERRKRIAERERERE 1515 Score = 65.9 bits (159), Expect = 8e-12 Identities = 31/122 (25%), Positives = 68/122 (55%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 K+ K + + +E++E+++ +E + + +++++ + + K E E+ + +++K Sbjct: 1364 KEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKK 1423 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120 KR+R + ++ E + EEEEEEKEEEE+EE ++++ + K +K+ RK Sbjct: 1424 KRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKI 1483 Query: 121 KK 122 K Sbjct: 1484 LK 1485 Score = 63.5 bits (153), Expect = 4e-11 Identities = 31/129 (24%), Positives = 72/129 (55%), Gaps = 7/129 (5%) Query: 1 KKKKKKKKETEETE-------ETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRK 53 ++KK K KE +E + +E++E+ + +E E+ E E+ + ++ + + + Sbjct: 1354 EEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELE 1413 Query: 54 EKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKK 113 E + K++K++R+ K +E+ E + EEE+EE+E+EE +++++ + ++ + Sbjct: 1414 ENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSP 1473 Query: 114 KKRRRKTKK 122 K R+K +K Sbjct: 1474 GKGRKKIRK 1482 Score = 59.3 bits (142), Expect = 7e-10 Identities = 29/123 (23%), Positives = 64/123 (52%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 K K K+ KE + + + E+ E ++ E+ E E +++ + +K + EE + Sbjct: 1357 KTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQ 1416 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120 + +++KK++ + +E+ E + EEEE+E+ +++++ +EE+E K K Sbjct: 1417 RSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKG 1476 Query: 121 KKK 123 +KK Sbjct: 1477 RKK 1479 Score = 58.9 bits (141), Expect = 9e-10 Identities = 35/130 (26%), Positives = 64/130 (49%), Gaps = 11/130 (8%) Query: 3 KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKET-------EKRKEK 55 KK+ K+ EE EE + + E + +K + + + + K T E++K K Sbjct: 1300 KKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTK 1359 Query: 56 EEEEKKRKRKRKKKKEEEEREEEEEEE----EEEKEEEEKEEGRRRKKKKKRRRKEEEEE 111 +E K+ K + ++K E+ E+ + +E EE E E+++ R R KK + + Sbjct: 1360 PKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSY 1419 Query: 112 KKKKRRRKTK 121 K+KK+RR+ K Sbjct: 1420 KQKKKRRRIK 1429 Score = 58.9 bits (141), Expect = 9e-10 Identities = 31/121 (25%), Positives = 67/121 (55%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 ++ K+KK+ + E++ E + + +E+ KE+ +E+E++++ +E ++ + + K Sbjct: 1416 QRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGK 1475 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120 RK+ RK K+++ R E + +EE+E ++ R R+++K R E E+ K T Sbjct: 1476 GRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIEDASPTKCPITT 1535 Query: 121 K 121 K Sbjct: 1536 K 1536 Score = 52.0 bits (123), Expect = 1e-07 Identities = 35/117 (29%), Positives = 59/117 (50%), Gaps = 10/117 (8%) Query: 3 KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKR 62 + K E EE E+ EE EEEEE+E + +++ + + + +KK ++ K ++K R Sbjct: 1437 ENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILK------DDKLR 1490 Query: 63 KRKRKKKKEEEERE----EEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKK 115 + KEEEER E E E E+ +E E E+ K + +E+E+ K+ Sbjct: 1491 TETQNALKEEEERRKRIAEREREREKLREVIEIEDASPTKCPITTKLVLDEDEETKE 1547 Score = 49.7 bits (117), Expect = 6e-07 Identities = 34/129 (26%), Positives = 60/129 (46%), Gaps = 14/129 (10%) Query: 8 KETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRK 67 K ++E +++E E+ KR K+ E+ E+ K +E + EE +K R R R Sbjct: 1281 KANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRL 1340 Query: 68 KKKEEEEREEEEEEEEEEKEEEEKE-EGRRRKKKKKRRRKE-------------EEEEKK 113 + + + E EE++ K +E KE +GR R+K ++ E E+++ Sbjct: 1341 LRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQ 1400 Query: 114 KKRRRKTKK 122 + R R KK Sbjct: 1401 RPRTRSAKK 1409 Score = 45.1 bits (105), Expect = 1e-05 Identities = 41/131 (31%), Positives = 65/131 (49%), Gaps = 12/131 (9%) Query: 4 KKKKKETEETEETEETEEEEEKEGKRKEKRK---------EKRKEKEKKKKTKETEKRKE 54 K++ + E + ET+E+ K K K +K EK +K++ +T E +K++ Sbjct: 927 KEQSFTSLEVRKVAETKEKS-KHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQS 985 Query: 55 KE-EEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKK 113 K+ EEKK+ KKK + E++ E + EK E +E K K+ + + EKK Sbjct: 986 KKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKK 1045 Query: 114 -KKRRRKTKKK 123 KK R KT KK Sbjct: 1046 SKKIRDKTSKK 1056 Score = 44.3 bits (103), Expect = 2e-05 Identities = 35/145 (24%), Positives = 70/145 (48%), Gaps = 22/145 (15%) Query: 1 KKKKKK-------KKETEETEETEETEEEEEKEGKR-KEKRKEKRKEKEKKKK----TKE 48 K KKK +K T + + + +E+++ K G +EK++ K K +K+ + + Sbjct: 1052 KTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSD 1111 Query: 49 TEKRKEKEE----EEKKRKR----KRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKK 100 TEK KE+ +K+ KR +R+ + +E + EE E+ +++K++ Sbjct: 1112 TEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQR 1171 Query: 101 KKRRRKE--EEEEKKKKRRRKTKKK 123 ++K +E+K+ R TK+K Sbjct: 1172 TSSKKKAVIVKEKKRNSLRTSTKRK 1196 Score = 43.5 bits (101), Expect = 4e-05 Identities = 32/134 (23%), Positives = 64/134 (47%), Gaps = 13/134 (9%) Query: 3 KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEE----- 57 KK + ET E ++ + + EEK+ K+K + E++ + + TEK E+EE Sbjct: 970 KKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFP 1029 Query: 58 ---EEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGR-----RRKKKKKRRRKEEE 109 ++ K +KK ++ R++ ++++E + EK G+ + KK + Sbjct: 1030 KGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGR 1089 Query: 110 EEKKKKRRRKTKKK 123 E+K+ K K+ +K Sbjct: 1090 EKKRCKLLGKSSRK 1103 Score = 38.5 bits (88), Expect = 0.001 Identities = 24/91 (26%), Positives = 45/91 (49%), Gaps = 3/91 (3%) Query: 5 KKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKR 64 KKK++T+ E+ + E EKE K K R K++ TK+ + ++++ +K Sbjct: 805 KKKRQTQS--ESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDN 862 Query: 65 K-RKKKKEEEEREEEEEEEEEEKEEEEKEEG 94 + K K +E ++ E ++E+E EG Sbjct: 863 QGHKNLKTSQEGSSDDAERKQERETFSSAEG 893 Score = 37.7 bits (86), Expect = 0.002 Identities = 43/179 (24%), Positives = 70/179 (39%), Gaps = 57/179 (31%) Query: 2 KKKKKKKETEETEETEETEEEEEKE-------GKRKEKRKEKRKEKEKKKKTKETEKRKE 54 KKK K E + ++ TE+ E+E G ++ K EK+ KK +T K+K+ Sbjct: 999 KKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKD 1058 Query: 55 K----------------EEEEKK-------RKRKRKKKKEEEEREEEEEEEEEEKEEEEK 91 + E+KK R++KR K + R+ ++ + ++ K Sbjct: 1059 ELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMK 1118 Query: 92 EEGRRRKKKK--------------KRRRKE-------------EEEEKKKKRRRKTKKK 123 E+G K+ KR KE E+ KKKK+R +KKK Sbjct: 1119 EDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKK 1177 Score = 37.0 bits (84), Expect = 0.004 Identities = 24/101 (23%), Positives = 43/101 (42%), Gaps = 1/101 (0%) Query: 3 KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKR 62 K+ K+ E E +E + E+ E KKKK + + K+K +EKKR Sbjct: 1127 KRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKR 1186 Query: 63 KRKR-KKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKK 102 R K+++ + + E+ ++ EG ++K K Sbjct: 1187 NSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIK 1227 Score = 35.4 bits (80), Expect = 0.011 Identities = 16/91 (17%), Positives = 40/91 (43%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61 ++++ T+E + + E ++ +K+K++ KKK EK++ K Sbjct: 1135 RERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTK 1194 Query: 62 RKRKRKKKKEEEEREEEEEEEEEEKEEEEKE 92 RK+ + E++++ E +E++ Sbjct: 1195 RKQADITSSSSSDIEDDDQNSIGEGSSDEQK 1225 Score = 35.0 bits (79), Expect = 0.014 Identities = 21/117 (17%), Positives = 54/117 (46%), Gaps = 9/117 (7%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKR--KEKRKEKEKKKKTKETEKRKEKEEE 58 K K+K+K T ++ + K+GK + +K+++ + + ++E KE + Sbjct: 776 KGKRKRKSSTSGSDF-------DTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSM 828 Query: 59 EKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKK 115 K + KK+ ++ + E+E+ ++ +G + K + ++ E K+++ Sbjct: 829 SKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQER 885 Score = 33.9 bits (76), Expect = 0.032 Identities = 31/127 (24%), Positives = 60/127 (47%), Gaps = 16/127 (12%) Query: 3 KKKKKKET----EETEETEETEEEEEKEGKRKEKRK------EKRKEKEKKKKTKETEKR 52 ++K+++ET E T + + T E +K++ +K KE+ + E K Sbjct: 880 ERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKV 939 Query: 53 KEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEK 112 E +E+ K K K KK ++ + E+ ++++ +E E+ KK+ +K EE+K Sbjct: 940 AETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDD------KKQSKKGTEEKK 993 Query: 113 KKKRRRK 119 K +K Sbjct: 994 KPSDFKK 1000 Score = 33.5 bits (75), Expect = 0.042 Identities = 31/118 (26%), Positives = 58/118 (49%), Gaps = 10/118 (8%) Query: 1 KKKKK----KKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKE 56 ++KKK KKK + ++ E + + EK +R+E + K+ K T + EK K K+ Sbjct: 990 EEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEK-KSKK 1048 Query: 57 EEEKKRKRKRKKK--KEEEEREEEEEEEEEEKEEEEKEEGRRRKKKK---KRRRKEEE 109 +K K+K + E+ + + + E+K+ + GR +K+ K K RK ++ Sbjct: 1049 IRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQD 1106 Score = 33.1 bits (74), Expect = 0.054 Identities = 18/86 (20%), Positives = 41/86 (47%) Query: 34 KEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEE 93 K+ + ++++K T ++ +K + K +KK++ + E + E E+E + K Sbjct: 773 KDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIG 832 Query: 94 GRRRKKKKKRRRKEEEEEKKKKRRRK 119 R KK+ K+ + + +K +K Sbjct: 833 AARTTKKRIPNTKDFDSSEDEKHSKK 858 Score = 31.6 bits (70), Expect = 0.16 Identities = 22/99 (22%), Positives = 44/99 (44%), Gaps = 4/99 (4%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 K++ +TE+ E+ +K KR E R+ R+ K+ TKE + + E+ Sbjct: 1103 KRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRE--RRNLSSKRNTKEIQSGSSSSDAEE 1160 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKK 99 + +KKK + +++ +EK+ +RK+ Sbjct: 1161 SSEDNKKKK--QRTSSKKKAVIVKEKKRNSLRTSTKRKQ 1197 Score = 31.6 bits (70), Expect = 0.16 Identities = 16/91 (17%), Positives = 39/91 (42%), Gaps = 2/91 (2%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 ++ K+ T+E + + + EE K+K++R +KK + +KR K Sbjct: 1137 RRNLSSKRNTKEIQSGSSSSDAEESS--EDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTK 1194 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEK 91 +++ + ++++ E +E+K Sbjct: 1195 RKQADITSSSSSDIEDDDQNSIGEGSSDEQK 1225 Score = 31.6 bits (70), Expect = 0.16 Identities = 22/126 (17%), Positives = 52/126 (41%), Gaps = 13/126 (10%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEK-------------EKKKKTKE 48 K+K+ + + + E+ ++ EG E++ + E + +K Sbjct: 1194 KRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKS 1253 Query: 49 TEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEE 108 + ++++ + + KK EE + +E+ ++E EEG++R K+ + Sbjct: 1254 VPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGD 1313 Query: 109 EEEKKK 114 EE K + Sbjct: 1314 EEAKNQ 1319 Score = 30.8 bits (68), Expect = 0.27 Identities = 21/96 (21%), Positives = 40/96 (41%), Gaps = 1/96 (1%) Query: 15 ETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK-RKRKRKKKKEEE 73 E + E + KEK ++ K + K +TK + K E+K K + K +++ Sbjct: 410 EEDLNSEFRAMDAVNKEKNTKEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQV 469 Query: 74 EREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEE 109 + E + E++ K G KK ++ + E Sbjct: 470 DSEHMHQNVPTEEQRTNKSTGGEHKKSDRKEEPQYE 505 Score = 30.8 bits (68), Expect = 0.27 Identities = 22/96 (22%), Positives = 42/96 (43%), Gaps = 4/96 (4%) Query: 20 EEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEE----EKKRKRKRKKKKEEEER 75 EE+ E + + +++ KE K + E + K E+ EKK K + K ++ Sbjct: 410 EEDLNSEFRAMDAVNKEKNTKEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQV 469 Query: 76 EEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEE 111 + E + EE+ + + KK R++E + E Sbjct: 470 DSEHMHQNVPTEEQRTNKSTGGEHKKSDRKEEPQYE 505 Score = 30.0 bits (66), Expect = 0.46 Identities = 19/88 (21%), Positives = 43/88 (48%), Gaps = 5/88 (5%) Query: 6 KKKETEETEETEETEEEEEKEGKRK---EKRKEKRKEKEKKKKTKETEKRKEK--EEEEK 60 K+K T+E + + E + ++G++ EK+ + E + +K ++E + EE++ Sbjct: 425 KEKNTKEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPTEEQR 484 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEE 88 K + K+ + +EE + E E+ Sbjct: 485 TNKSTGGEHKKSDRKEEPQYEPANTSED 512 Score = 29.6 bits (65), Expect = 0.60 Identities = 24/116 (20%), Positives = 45/116 (38%), Gaps = 16/116 (13%) Query: 19 TEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEE 78 T ++++ + + + +K +E K E +E E+ +KR K + E Sbjct: 1257 TVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGK-----QNEENP 1311 Query: 79 EEEEEEEKEEEEKEEGRRRKKKKKRRRK-----------EEEEEKKKKRRRKTKKK 123 +EE + + E + KK + R + E EEKK K + + K Sbjct: 1312 GDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVK 1367 Score = 28.9 bits (63), Expect = 1.0 Identities = 19/87 (21%), Positives = 33/87 (37%), Gaps = 2/87 (2%) Query: 8 KETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRK-- 65 +E+EET + + E K++ T +EK K KRK Sbjct: 27 EESEETSSPPRLAMNQNTDKISGSGSNSDMMENSKEEGTSSSEKSKSSGSSRSKRKPSIV 86 Query: 66 RKKKKEEEEREEEEEEEEEEKEEEEKE 92 K + ++E+ ++E E+ E E Sbjct: 87 TKYVESDDEKPLDDETVNEDASNENSE 113 Score = 28.5 bits (62), Expect = 1.3 Identities = 22/113 (19%), Positives = 50/113 (44%), Gaps = 2/113 (1%) Query: 11 EETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKK 70 +E E E +K+ E R K+++ T +K KE+ + + K Sbjct: 883 QERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVR--KVA 940 Query: 71 EEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123 E +E+ + + + +K ++ + + KK + + E++KK+ ++ +KK Sbjct: 941 ETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKK 993 Score = 26.2 bits (56), Expect = 6.7 Identities = 12/49 (24%), Positives = 24/49 (48%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETE 50 K +K+ ++E + TEE+ + E +K RKE+ + + +E Sbjct: 463 KLSRKQVDSEHMHQNVPTEEQRTNKSTGGEHKKSDRKEEPQYEPANTSE 511 Score = 26.2 bits (56), Expect = 6.7 Identities = 19/119 (15%), Positives = 47/119 (39%), Gaps = 5/119 (4%) Query: 7 KKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKR 66 ++ TE T ++EE + K K+K ++K+K+ + + + K ++ + Sbjct: 665 RRPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSET 724 Query: 67 KKKKEEEER-----EEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120 + + + +E + + E K + + ++ K KR+RK+ Sbjct: 725 VDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKS 783 >gi|239750213 PREDICTED: hypothetical protein [Homo sapiens] Length = 248 Score = 76.6 bits (187), Expect = 4e-15 Identities = 44/116 (37%), Positives = 72/116 (62%), Gaps = 6/116 (5%) Query: 8 KETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRK 67 +E ++ E+ EKE K RK+K +K+KKKKT T K+K+K +KK K K Sbjct: 2 QELDKGVAMEKVHVITEKESAWKRGRKKKTTKKKKKKKT--TMKKKKKTTTKKKTTTKTK 59 Query: 68 KKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123 K+ ++ +E+EKE+E+++E K+K+K + KE+E++KKKK+++K KKK Sbjct: 60 KRTTTTKKTTTTTTKEKEKEKEKEKE----KEKEKEKEKEKEKKKKKKKKKKKKKK 111 Score = 76.3 bits (186), Expect = 6e-15 Identities = 36/96 (37%), Positives = 68/96 (70%), Gaps = 1/96 (1%) Query: 19 TEEEEE-KEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREE 77 TE+E K G++K+ K+K+K+K KK K+T +K+ + KKR KK +E+ Sbjct: 17 TEKESAWKRGRKKKTTKKKKKKKTTMKKKKKTTTKKKTTTKTKKRTTTTKKTTTTTTKEK 76 Query: 78 EEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKK 113 E+E+E+E+++E+EKE+ + ++KKKK+++K+++++KK Sbjct: 77 EKEKEKEKEKEKEKEKEKEKEKKKKKKKKKKKKKKK 112 Score = 65.5 bits (158), Expect = 1e-11 Identities = 37/106 (34%), Positives = 66/106 (62%), Gaps = 14/106 (13%) Query: 2 KKKKKKKETEETEETEETEEEEEKEG-KRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 K+ +KKK T++ ++ + T ++++K K+K K K++ KK T T K KEKE Sbjct: 24 KRGRKKKTTKKKKKKKTTMKKKKKTTTKKKTTTKTKKRTTTTKKTTTTTTKEKEKE---- 79 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRK 106 KE+E+ +E+E+E+E+EKE+++K++ +++KKKKK K Sbjct: 80 ---------KEKEKEKEKEKEKEKEKEKKKKKKKKKKKKKKKLNAK 116 Score = 65.5 bits (158), Expect = 1e-11 Identities = 39/75 (52%), Positives = 52/75 (69%), Gaps = 9/75 (12%) Query: 1 KKKKK---KKKETEETEE-TEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKE 56 KKKKK KKK T +T++ T T++ K KEK KEK KEKEK+K EK KEKE Sbjct: 43 KKKKKTTTKKKTTTKTKKRTTTTKKTTTTTTKEKEKEKEKEKEKEKEK-----EKEKEKE 97 Query: 57 EEEKKRKRKRKKKKE 71 +++KK+K+K+KKKK+ Sbjct: 98 KKKKKKKKKKKKKKK 112 >gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 724 Score = 76.6 bits (187), Expect = 4e-15 Identities = 35/123 (28%), Positives = 89/123 (72%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 +++K +++E + E+ E T+E+EEK G+++EK E+ ++ +++++ ++ K +E+E+K Sbjct: 590 QEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKK 649 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120 R+++ K +++EE +E+EE+ E++E+ ++E + +++++K RR+EE+ +++ R R+ Sbjct: 650 IREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQ 709 Query: 121 KKK 123 ++K Sbjct: 710 EEK 712 Score = 75.1 bits (183), Expect = 1e-14 Identities = 44/137 (32%), Positives = 88/137 (64%), Gaps = 15/137 (10%) Query: 1 KKKKKKKKET------EETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEK--- 51 K++K +++E E+ E EE E+EK +++EKR+E+ K +E++K+ ++ K Sbjct: 422 KEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWR 481 Query: 52 --RKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKR----RR 105 K +E+EEK R+++ K ++EE+ E+E+ EEEK +E++E R+ +K +++ R+ Sbjct: 482 QEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQ 541 Query: 106 KEEEEEKKKKRRRKTKK 122 KE+ E+++K R++ +K Sbjct: 542 KEKIHEQEEKIRKQEEK 558 Score = 72.0 bits (175), Expect = 1e-13 Identities = 38/130 (29%), Positives = 90/130 (69%), Gaps = 7/130 (5%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEK---RKEKRKEKEKKKKTKET----EKRK 53 ++++K +++ E + E+ E+EEK K++EK ++EK ++E+K + +E ++ K Sbjct: 527 RQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEK 586 Query: 54 EKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKK 113 +E+EEK R+++ K +++EE +E+EE+ E++E+ ++E + +++++K RR+EE+ ++ Sbjct: 587 IREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQ 646 Query: 114 KKRRRKTKKK 123 +K+ R+ ++K Sbjct: 647 EKKIREQEEK 656 Score = 72.0 bits (175), Expect = 1e-13 Identities = 35/124 (28%), Positives = 85/124 (68%), Gaps = 2/124 (1%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 ++++K ++ E+ E EE E+E++ + +E+ ++++EK +++ K E+ ++ +E+E+ Sbjct: 575 EQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEE 634 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEE--EEKEEGRRRKKKKKRRRKEEEEEKKKKRRR 118 K +R+ +K +E+E++ E+EE+ E+EE +E+EE +++K ++E+ +E+++K RR Sbjct: 635 KMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRR 694 Query: 119 KTKK 122 + +K Sbjct: 695 QEEK 698 Score = 70.9 bits (172), Expect = 2e-13 Identities = 41/129 (31%), Positives = 85/129 (65%), Gaps = 8/129 (6%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEK--RKEKRKEKEKKKKTKETEKRKEKEE-- 57 ++++K++E EE EE E+E+ ++KEK +E++ K+++K ++ EK ++EE Sbjct: 514 REEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKI 573 Query: 58 --EEKKRKRKRKKKKEEEEREEEEEEEEEEKEE--EEKEEGRRRKKKKKRRRKEEEEEKK 113 +E+K R+ +K +E+EE+ E+EE+ E+EE +E+EE +++K ++E+ +E++ Sbjct: 574 REQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQE 633 Query: 114 KKRRRKTKK 122 +K RR+ +K Sbjct: 634 EKMRRQEEK 642 Score = 69.7 bits (169), Expect = 5e-13 Identities = 35/125 (28%), Positives = 82/125 (65%), Gaps = 3/125 (2%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEK---EKKKKTKETEKRKEKEEE 58 ++++K +E EE + +E + E++E R+++ K +R+E+ EK++K + E+ ++EE Sbjct: 365 RQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 424 Query: 59 EKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRR 118 + +R+ + +KEE+ RE EE+ E+EK E++E+ + +K +++ +++E+E K ++ Sbjct: 425 KMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEE 484 Query: 119 KTKKK 123 K +++ Sbjct: 485 KIREQ 489 Score = 68.9 bits (167), Expect = 9e-13 Identities = 41/127 (32%), Positives = 84/127 (66%), Gaps = 9/127 (7%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 +K++K +++ E E EE E E++ +EK +E+ +++++++K +E EKR +E+E Sbjct: 421 EKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKR---QEQEA 477 Query: 61 KRKRKRKKKKEEEEREEEEEE----EEEEKEEEEK--EEGRRRKKKKKRRRKEEEEEKKK 114 K R+ +K +E+EE+ E+EE +EE+ E+EK EE +R+++++ R++E+ E+++ Sbjct: 478 KMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEE 537 Query: 115 KRRRKTK 121 R+K K Sbjct: 538 IWRQKEK 544 Score = 68.6 bits (166), Expect = 1e-12 Identities = 34/123 (27%), Positives = 81/123 (65%), Gaps = 1/123 (0%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 K++K +++E E+ E+ +EE +++EK +E ++ +++K +E E++++ EEE+ Sbjct: 408 KEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQ-EEEKI 466 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120 + + KR++++ + R+EE+ E+EEK E++E+ R+++K + K EEEK++++ Sbjct: 467 REQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMW 526 Query: 121 KKK 123 +++ Sbjct: 527 RQE 529 Score = 68.6 bits (166), Expect = 1e-12 Identities = 39/145 (26%), Positives = 93/145 (64%), Gaps = 22/145 (15%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 +K++K ++ E+ E E+ E+EEK + ++ R+++++++++ K ++ EK +E+EE+ + Sbjct: 435 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 494 Query: 61 KRKRK----------RKKKKEEEEREEEEE---EEEEEKEEEE---------KEEGRRRK 98 +++ K ++K +EEE+R+E+EE +EE+ +E+EE ++E + RK Sbjct: 495 EQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRK 554 Query: 99 KKKKRRRKEEEEEKKKKRRRKTKKK 123 +++K R+EE+ ++++ R+ ++K Sbjct: 555 QEEKMWRQEEKMHDQEEKIREQEEK 579 Score = 68.6 bits (166), Expect = 1e-12 Identities = 36/128 (28%), Positives = 88/128 (68%), Gaps = 5/128 (3%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKR---KEKEKKKKTKETEKRKEK-- 55 +++++K +E EE +E + E+++ + +EKR+E+ +++EK ++ +E ++KEK Sbjct: 487 REQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIH 546 Query: 56 EEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKK 115 E+EEK RK++ K ++EE+ ++EE+ E++E+ ++E + R++++K R +EE+ ++++ Sbjct: 547 EQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEE 606 Query: 116 RRRKTKKK 123 ++ ++K Sbjct: 607 MTQEQEEK 614 Score = 68.6 bits (166), Expect = 1e-12 Identities = 51/148 (34%), Positives = 91/148 (61%), Gaps = 28/148 (18%) Query: 3 KKKKKKETEETEETEETEEEEEKEGKRKE--KRKEKRKEKEKKKKTKE------------ 48 +++K +E E+ +E EE +EEK +++E ++KEK E+E+K + +E Sbjct: 509 EQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHD 568 Query: 49 -TEKRKEKEE-----EEKKRKRKRKKKKEEEEREEEEE--EEEEEK--EEEEK----EEG 94 EK +E+EE EEK R+++ K +++EE+ E+EE +E+EEK E+EEK EE Sbjct: 569 QEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEK 628 Query: 95 RRRKKKKKRRRKEEEEEKKKKRRRKTKK 122 + +++K RR++E+ E++KK R + +K Sbjct: 629 MQEQEEKMRRQEEKIREQEKKIREQEEK 656 Score = 68.2 bits (165), Expect = 2e-12 Identities = 39/126 (30%), Positives = 80/126 (63%), Gaps = 8/126 (6%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKE---KRKEKRKEKEKKKKTKETEKRKEKE-- 56 ++K +++E + E+ E+ E+EEK +++E +++EK + +E+ KE + R+++E Sbjct: 374 EEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMM 433 Query: 57 --EEEKKRKRKRKKKKEEEEREEEEEEEEEEK-EEEEKEEGRRRKKKKKRRRKEEEEEKK 113 +EEK R+ + K ++E+ RE+EE+ +EEEK E+EK + + K ++ + E+EEK Sbjct: 434 WEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKI 493 Query: 114 KKRRRK 119 +++ K Sbjct: 494 REQEEK 499 Score = 68.2 bits (165), Expect = 2e-12 Identities = 45/147 (30%), Positives = 93/147 (63%), Gaps = 26/147 (17%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEK---RKEKRKEKEKK-----------KKT 46 +++++K++E E+ E E+ +E+E K +++EK ++EK +E+E+K +K Sbjct: 454 REQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKI 513 Query: 47 KETEKRKEKEE----EEKKRK-----RKRKKKKEEEEREEEEEEE---EEEKEEEEKEEG 94 +E EKR+E+EE EEK R+ R+++K E+EE+ ++EE+ +EEK +++E+ Sbjct: 514 REEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKI 573 Query: 95 RRRKKKKKRRRKEEEEEKKKKRRRKTK 121 R +++K R+ ++ E+++K R ++ K Sbjct: 574 REQEEKVWRQEEKIREQEEKIREQEEK 600 Score = 67.0 bits (162), Expect = 3e-12 Identities = 31/121 (25%), Positives = 79/121 (65%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 ++++K ++ E+ +E EE +E+E++ + +E++ +++EK ++++ EK ++ +E+ Sbjct: 358 QQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEE 417 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120 K +K + +EE E+EE+ E EE+ E+ + R++++KR+ +E+ E++K++ ++ Sbjct: 418 MMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEA 477 Query: 121 K 121 K Sbjct: 478 K 478 Score = 67.0 bits (162), Expect = 3e-12 Identities = 32/121 (26%), Positives = 80/121 (66%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 ++++K +++ E+ EE E+E++ +R+E+ +++EK ++++ EK ++ E E+ Sbjct: 386 EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEE 445 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120 K + K +++EE+R+EEE+ E+EK +E++ + R+++K + + ++ E+++K R++ Sbjct: 446 KMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEE 505 Query: 121 K 121 K Sbjct: 506 K 506 Score = 67.0 bits (162), Expect = 3e-12 Identities = 36/121 (29%), Positives = 78/121 (64%), Gaps = 1/121 (0%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61 ++++K E E+ E E+ +E+EE +++EK +E+ + +K+K E E++ K+EE+ Sbjct: 502 RQEEKIHEQEKIREEEKRQEQEEM-WRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMW 560 Query: 62 RKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTK 121 R+ ++ +EE+ RE+EE+ +E++ E+EE R +++K R ++E +E+++K + + Sbjct: 561 RQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEE 620 Query: 122 K 122 K Sbjct: 621 K 621 Score = 67.0 bits (162), Expect = 3e-12 Identities = 34/124 (27%), Positives = 87/124 (70%), Gaps = 2/124 (1%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKR-KEKRKEKEKKKKTKETEKRKEKEEEE 59 +++K +K+E + + E+ ++EEK +++EK +++ K +E+++K +E E+ K +E+EE Sbjct: 548 QEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEE-KIREQEE 606 Query: 60 KKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRK 119 ++++ K ++EE+ E+EE+ +E++E+ ++E + R+++KK R +EE+ ++++ ++ Sbjct: 607 MTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQE 666 Query: 120 TKKK 123 ++K Sbjct: 667 QEEK 670 Score = 66.6 bits (161), Expect = 4e-12 Identities = 32/124 (25%), Positives = 84/124 (67%), Gaps = 2/124 (1%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 K+++K ++ E+ + EE E+E++ R+E++ +++EK ++++ K E+ + +E+E+ Sbjct: 554 KQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEE 613 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEE--EEKKKKRRR 118 K + +K E+EE+ +E+EE+ +EE+ +E+ ++ ++++++ R++EE +E+++K Sbjct: 614 KMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWE 673 Query: 119 KTKK 122 + +K Sbjct: 674 QEEK 677 Score = 65.9 bits (159), Expect = 8e-12 Identities = 35/122 (28%), Positives = 83/122 (68%), Gaps = 4/122 (3%) Query: 6 KKKETEETEETEETEEEEEKEGKRKEK-RKEKRKEKEKKKKTKETEKRKEKEEEEKKRKR 64 +++E + + E+ +E EEK +++EK R+++ K +E+++K + E+ ++EE+ +R+ Sbjct: 357 QQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQE 416 Query: 65 KRKKKKEEEEREEEE---EEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTK 121 + +KEE+ R +EE E+EE+ +E EEK + + ++++ +R+EEE+ +++++R++ + Sbjct: 417 EMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE 476 Query: 122 KK 123 K Sbjct: 477 AK 478 Score = 65.5 bits (158), Expect = 1e-11 Identities = 33/121 (27%), Positives = 81/121 (66%), Gaps = 1/121 (0%) Query: 3 KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKR 62 +++++K + E+ +E EE+ +++ ++ +++EK +E+E+K + +E E EKEE+ +++ Sbjct: 357 QQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQE-EMMWEKEEKMRRQ 415 Query: 63 KRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKK 122 + +K+E+ R+EE E+EEK E +E+ ++K +++ K +EEEK +++ ++ ++ Sbjct: 416 EEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQ 475 Query: 123 K 123 + Sbjct: 476 E 476 Score = 65.1 bits (157), Expect = 1e-11 Identities = 35/126 (27%), Positives = 82/126 (65%), Gaps = 5/126 (3%) Query: 3 KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKR 62 ++K +++ E+ E EE E+E++ +R+E+ +++EK ++++ EK ++ +E+ Sbjct: 374 EEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMM 433 Query: 63 KRKRKKKKEEEEREEEEEE--EEEEKEEEE---KEEGRRRKKKKKRRRKEEEEEKKKKRR 117 K +K +E EE+ E+E+ E+EEK +EE +E+ +R++++ K R+EE+ +++++ Sbjct: 434 WEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKI 493 Query: 118 RKTKKK 123 R+ ++K Sbjct: 494 REQEEK 499 Score = 65.1 bits (157), Expect = 1e-11 Identities = 36/131 (27%), Positives = 82/131 (62%), Gaps = 8/131 (6%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEE--- 57 ++++K +++ E+ E EE +E++ +EK +E+ K +E+++ ++ EK +E+EE Sbjct: 481 RQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWR 540 Query: 58 -EEKKRKRKRKKKKEEEEREEEEE----EEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEK 112 +EK +++ K +K+EE+ +EE +EE+ +E+EEK + K +++ + E+EEK Sbjct: 541 QKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEK 600 Query: 113 KKKRRRKTKKK 123 +++ T+++ Sbjct: 601 IREQEEMTQEQ 611 Score = 65.1 bits (157), Expect = 1e-11 Identities = 35/127 (27%), Positives = 83/127 (65%), Gaps = 4/127 (3%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEK-RKEKRKEKEKKKKTKETEKRKEKEEEE 59 +++K +E + E+ E+ +EEK +++EK R+++ K +E+++ T+E E++ ++EE+ Sbjct: 562 QEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEK 621 Query: 60 KKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKE---EEEEKKKKR 116 + ++ +++EE+ R +EE+ E+EK+ E+EE R +++ + ++E E+EEK ++ Sbjct: 622 MCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQ 681 Query: 117 RRKTKKK 123 K +++ Sbjct: 682 EEKMQEQ 688 Score = 64.7 bits (156), Expect = 2e-11 Identities = 33/112 (29%), Positives = 78/112 (69%), Gaps = 2/112 (1%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEK-RKEKRKEKEKKKKTKETEKRKEKEEEE 59 +++K ++E + E+ E+ +E+EEK +++EK R++++K +E+++K +E E+ + E+EE Sbjct: 611 QEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQ-EQEE 669 Query: 60 KKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEE 111 K +++ K ++EE+ +E+EE+ ++E+ ++E R R++++K + +E E Sbjct: 670 KMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLE 721 Score = 62.4 bits (150), Expect = 8e-11 Identities = 34/121 (28%), Positives = 76/121 (62%), Gaps = 2/121 (1%) Query: 5 KKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEK--EKKKKTKETEKRKEKEEEEKKR 62 K + + EE E +++E++ R+E++ ++ +EK E+++K +E E++ ++EE+ +R Sbjct: 341 KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRR 400 Query: 63 KRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKK 122 + + +KEE+ R +EE E+E++ +EE K++K R +E+ E++K R ++ K+ Sbjct: 401 QEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKR 460 Query: 123 K 123 + Sbjct: 461 Q 461 Score = 55.1 bits (131), Expect = 1e-08 Identities = 33/115 (28%), Positives = 69/115 (60%), Gaps = 1/115 (0%) Query: 8 KETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRK 67 KE + + + EE + R +++E++ ++++K + EK +E+EE+ ++++ K + Sbjct: 333 KELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIR 392 Query: 68 KKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKK 122 +++E+ R+EE E+EEK + EE K++K RR++E EK++K R +K Sbjct: 393 EQEEKMRRQEEMMWEKEEKMRRQ-EEMMWEKEEKMRRQEEMMWEKEEKIRELEEK 446 Score = 49.3 bits (116), Expect = 7e-07 Identities = 33/126 (26%), Positives = 72/126 (57%), Gaps = 9/126 (7%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 K+ K+K + + ++ + E + GK E + K + + ++ + + +++EE+ Sbjct: 306 KELKRKLERAKLLLPQQQLQAEADHLGK--ELQSVSAKLQAQVEENELWNRLNQQQEEKM 363 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRR-------KKKKKRRRKEEEEEKK 113 R+ ++ ++ EE+ +E+EE+ E+E++ E+EE RR K++K RR++E EK+ Sbjct: 364 WRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKE 423 Query: 114 KKRRRK 119 +K RR+ Sbjct: 424 EKMRRQ 429 Score = 48.5 bits (114), Expect = 1e-06 Identities = 39/138 (28%), Positives = 73/138 (52%), Gaps = 22/138 (15%) Query: 1 KKKKKKKKETEETEETEETEEE-EEKEGKRKEKR------------------KEKRKEKE 41 K+K K +E + E+E++E + KE KRK +R KE + Sbjct: 281 KEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSA 340 Query: 42 KKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKK 101 K + E + + ++++ K R+++K +E E+ +E+EE+ +E+EEK R +++K Sbjct: 341 KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEK---IREQEEK 397 Query: 102 KRRRKEEEEEKKKKRRRK 119 RR++E EK++K RR+ Sbjct: 398 MRRQEEMMWEKEEKMRRQ 415 Score = 38.1 bits (87), Expect = 0.002 Identities = 26/121 (21%), Positives = 62/121 (51%), Gaps = 1/121 (0%) Query: 4 KKKKKETEETEETEETEEEEEKEGKRKEKRK-EKRKEKEKKKKTKETEKRKEKEEEEKKR 62 K+K + +E + E+E+ E + ++ KRK E+ K +++ + KE + Sbjct: 281 KEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSA 340 Query: 63 KRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKK 122 K + + ++ E +++EE+ +EEK + K +++ + E+EEK +++ K ++ Sbjct: 341 KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRR 400 Query: 123 K 123 + Sbjct: 401 Q 401 >gi|84043963 eukaryotic translation initiation factor 5B [Homo sapiens] Length = 1220 Score = 76.6 bits (187), Expect = 4e-15 Identities = 41/119 (34%), Positives = 75/119 (63%), Gaps = 3/119 (2%) Query: 8 KETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKK---TKETEKRKEKEEEEKKRKR 64 +E ET E + E +K+ K K+K+K +++EKEK+KK +K T K ++ + K + Sbjct: 296 EEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEE 355 Query: 65 KRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123 +R+K++EEE + EE E + KEEE E+ +R +KK+K + ++E +K+ K K++++ Sbjct: 356 ERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQRE 414 Score = 74.7 bits (182), Expect = 2e-14 Identities = 53/162 (32%), Positives = 90/162 (55%), Gaps = 40/162 (24%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEK---RKEKEKKKKTKET-------- 49 KK++++KK EE + + +E+EE E +K++ K+K RK +E+ K+K T Sbjct: 235 KKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPA 294 Query: 50 --EKRK------EKEEEEKKRKRKRKKKKEEEEREEEE--------------------EE 81 EK + + E +KK+K K+KKK E+EE+E+E+ EE Sbjct: 295 SEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEE 354 Query: 82 EEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123 EE +K EEE E +R ++ + +R++EE E++K+ R+K K+K Sbjct: 355 EERQKREEE-ERIKRLEELEAKRKEEERLEQEKRERKKQKEK 395 Score = 73.9 bits (180), Expect = 3e-14 Identities = 35/112 (31%), Positives = 74/112 (66%) Query: 10 TEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKK 69 +EE ET E++ + K+K+ +K+K+ EKE+K+K K+ K + ++ K K++ Sbjct: 295 SEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEE 354 Query: 70 KEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTK 121 +E ++REEEE + E+ E +++E R +++K+ R+K++E+E+K++ +++ K Sbjct: 355 EERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGK 406 Score = 70.5 bits (171), Expect = 3e-13 Identities = 45/142 (31%), Positives = 83/142 (58%), Gaps = 21/142 (14%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKE--KRKEKRKEKEKKKKTKETEK-RKEKEE 57 +K +KK ++ + E E+++ K K ++K ++KE+E+KK+ +E K RK KE+ Sbjct: 197 RKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEK 256 Query: 58 EEKKRKRKRKKKKEEEEREEEEEEEE-------------EEKEE-----EEKEEGRRRKK 99 EE + +K + K++E +R+ EEE + EEK E E+ EG ++KK Sbjct: 257 EELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKK 316 Query: 100 KKKRRRKEEEEEKKKKRRRKTK 121 KK+++ E+EE++K+K++ +K Sbjct: 317 DKKKKKGEKEEKEKEKKKGPSK 338 Score = 70.5 bits (171), Expect = 3e-13 Identities = 43/115 (37%), Positives = 72/115 (62%), Gaps = 10/115 (8%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 KKKK KKK+ E +EE+EKE K+ + + +E K KE E+R+++EEEE+ Sbjct: 313 KKKKDKKKKKGE-------KEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEER 365 Query: 61 -KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKK 114 KR + + K++EEER E+E+ E ++++E+E++E R KK+ K K + E + + Sbjct: 366 IKRLEELEAKRKEEERLEQEKRERKKQKEKERKE--RLKKEGKLLTKSQREARAR 418 Score = 60.5 bits (145), Expect = 3e-10 Identities = 42/136 (30%), Positives = 72/136 (52%), Gaps = 19/136 (13%) Query: 6 KKKETE---ETEETEETEEE--EEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 +K+ET E EE E+TE+ ++ E ++ EK + + + KE + +E+EEEE+ Sbjct: 482 EKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEE 541 Query: 61 KRKRKRKKKKEEE-EREEEEEEEEEEKEEEEKEEGRRRKKKKKR-------------RRK 106 + + ++++EEE E E E +EE+EK +EK+ G+ KK + R K Sbjct: 542 EEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTK 601 Query: 107 EEEEEKKKKRRRKTKK 122 EE K KRR + ++ Sbjct: 602 EERAYDKAKRRIEKRR 617 Score = 58.9 bits (141), Expect = 9e-10 Identities = 39/146 (26%), Positives = 76/146 (52%), Gaps = 26/146 (17%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61 K K ++ E +E E + +EEK RK K KE+ E KK ++K+ E +++ EEE K Sbjct: 224 KIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEEL-ETGKKDQSKQKESQRKFEEETVK 282 Query: 62 RK--------RKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRR-------- 105 K ++K E E++ E +++K++++K++G + +K+K++++ Sbjct: 283 SKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVK 342 Query: 106 ---------KEEEEEKKKKRRRKTKK 122 KEEEE +K++ + K+ Sbjct: 343 AMQEALAKLKEEEERQKREEEERIKR 368 Score = 58.2 bits (139), Expect = 2e-09 Identities = 38/136 (27%), Positives = 72/136 (52%), Gaps = 15/136 (11%) Query: 1 KKKKKKKKETEETEETEETEEEE-EKEG----------KRKEKRKEKRKEKEKKKKTKET 49 KKK+KKK++ +E + +E EE E +G K E +E+ K+KKKK ++ Sbjct: 44 KKKEKKKQDFDEDDILKELEELSLEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKG 103 Query: 50 EKR----KEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRR 105 +K+ + EE E K + +K K + E +++++ + +K +G+ +K KK Sbjct: 104 KKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDG 163 Query: 106 KEEEEEKKKKRRRKTK 121 EE+E+ KK + +++ Sbjct: 164 SEEDEDNSKKIKERSR 179 Score = 57.8 bits (138), Expect = 2e-09 Identities = 30/113 (26%), Positives = 57/113 (50%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 +K + K E E EE EEEEE+E + +E +E+ +E E + + E K +E++ Sbjct: 516 EKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDS 575 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKK 113 + +K KE E + +++ KEE ++ +RR +K++ + +K Sbjct: 576 GKTLDKKPSKEMSSDSEYDSDDDRTKEERAYDKAKRRIEKRRLEHSKNVNTEK 628 Score = 57.0 bits (136), Expect = 4e-09 Identities = 40/135 (29%), Positives = 71/135 (52%), Gaps = 13/135 (9%) Query: 1 KKKKKKKKETEET------------EETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTK- 47 K+K+KKK ++ T EE E + EEE+ KR E+ + KRKE+E+ ++ K Sbjct: 328 KEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKR 387 Query: 48 ETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKE 107 E +K+KEKE +E+ +K + K + E E + + + E + KKR E Sbjct: 388 ERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYE 447 Query: 108 EEEEKKKKRRRKTKK 122 +++ KK ++ ++K+ Sbjct: 448 DKKRKKIPQQLESKE 462 Score = 56.2 bits (134), Expect = 6e-09 Identities = 41/137 (29%), Positives = 70/137 (51%), Gaps = 25/137 (18%) Query: 3 KKKKKKETEETEETEETEEEEEKEGKRKEKRK---------------EKRKEKEKKKKTK 47 KK K K + ++ + +EE+E+ K KE+ + + RK ++K +K K Sbjct: 148 KKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNK 207 Query: 48 ---ETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEK-----EEEEKEEGRR--R 97 E E ++ K K +KK E++ERE ++ +EE+ K E+EE E G++ Sbjct: 208 PGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQS 267 Query: 98 KKKKKRRRKEEEEEKKK 114 K+K+ +R+ EEE K K Sbjct: 268 KQKESQRKFEEETVKSK 284 Score = 56.2 bits (134), Expect = 6e-09 Identities = 30/116 (25%), Positives = 64/116 (55%), Gaps = 1/116 (0%) Query: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61 +K + K E +E E EEEEE+E + +++ E+ +E+E + + E ++ EK +EK Sbjct: 516 EKVEGNKVHIEVKENPE-EEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKD 574 Query: 62 RKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRR 117 + KK +E + E + ++++ +EE+ + +++ +KRR + + +K R Sbjct: 575 SGKTLDKKPSKEMSSDSEYDSDDDRTKEERAYDKAKRRIEKRRLEHSKNVNTEKLR 630 Score = 55.8 bits (133), Expect = 8e-09 Identities = 38/121 (31%), Positives = 65/121 (53%), Gaps = 9/121 (7%) Query: 3 KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKR 62 K K+++E ++ EE E + EE E KRKE E+R E+EK+ E++K+KE+E K+R Sbjct: 350 KLKEEEERQKREEEERIKRLEELEAKRKE---EERLEQEKR------ERKKQKEKERKER 400 Query: 63 KRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKK 122 +K K + +RE E K + + K ++R E++K+KK ++ + Sbjct: 401 LKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLES 460 Query: 123 K 123 K Sbjct: 461 K 461 Score = 55.8 bits (133), Expect = 8e-09 Identities = 39/138 (28%), Positives = 72/138 (52%), Gaps = 16/138 (11%) Query: 2 KKKKKKKETEETEETEETEE-----EEEKEGKRKEKRKEKRKEKEKKKKTKE-------- 48 KK+KK + E++E E+ E E ++G +++ E E+++ T++ Sbjct: 449 KKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEA 508 Query: 49 --TEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKE-EGRRRKKKKKRRR 105 +++ EK E K ++ +EEEE EEEEEE+EE +EEEE+E E + ++ + Sbjct: 509 MASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEK 568 Query: 106 KEEEEEKKKKRRRKTKKK 123 +E++ K +K K+ Sbjct: 569 VSDEKDSGKTLDKKPSKE 586 Score = 53.9 bits (128), Expect = 3e-08 Identities = 37/125 (29%), Positives = 63/125 (50%), Gaps = 3/125 (2%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKE--KEEE 58 K+K K + T++ + + E E G KE+ +K K K+KK+K K+ + KE E Sbjct: 4 KQKNKSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKELE 63 Query: 59 EKKRKRKR-KKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRR 117 E + + K +E + E EEE +++K++G++ KK+ EE E K + Sbjct: 64 ELSLEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKS 123 Query: 118 RKTKK 122 +KT K Sbjct: 124 KKTAK 128 Score = 52.0 bits (123), Expect = 1e-07 Identities = 39/165 (23%), Positives = 76/165 (46%), Gaps = 42/165 (25%) Query: 1 KKKKKK-KKETEETEETEETEEEEEKEGKRKEKRKEK-----------------RKEKEK 42 K KKKK +K +++ + ++EE E+K+ K K+ K K +K K K Sbjct: 94 KDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGK 153 Query: 43 KKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEE--------------------- 81 +K+ + E++E+ K+ ++R + E +E +E Sbjct: 154 AQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIE 213 Query: 82 ---EEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123 E+++ + K +++ +KK+R RK+ +EEK K R+ K K++ Sbjct: 214 SGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEE 258 Score = 51.6 bits (122), Expect = 1e-07 Identities = 32/117 (27%), Positives = 67/117 (57%), Gaps = 6/117 (5%) Query: 1 KKKKKKKKETEETEETEETEEE-EEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEE 59 KK K++ + E +E++E + ++G++K ++ + E + + + + ++ Sbjct: 172 KKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQK 231 Query: 60 KKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRR-RKKKKKRRRKEEEEEKKKK 115 K K++R++KK R+EE+ + + KE+EE E G++ + K+K+ +RK EEE K K Sbjct: 232 KAEKKERERKK----RDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSK 284 Score = 50.1 bits (118), Expect = 4e-07 Identities = 29/110 (26%), Positives = 60/110 (54%), Gaps = 1/110 (0%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 ++K+++++ + EE E +EEE+ + K +RK K+KEKE+K++ K+ K K + E Sbjct: 357 RQKREEEERIKRLEELEAKRKEEERLEQEKRERK-KQKEKERKERLKKEGKLLTKSQREA 415 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEE 110 + + + K + + E ++ K+ E+ +R+K ++ KE E Sbjct: 416 RARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSE 465 Score = 45.1 bits (105), Expect = 1e-05 Identities = 32/137 (23%), Positives = 65/137 (47%), Gaps = 20/137 (14%) Query: 5 KKKKETEETEETEETEEEEEKEGKRKEKRKEKRK-----------EKEKKKKTKETEKRK 53 K +ET + TE EEE + K+K+ +K K++ +K+ K+K+T K K Sbjct: 73 KADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKD--SKSKKTAKPK 130 Query: 54 -------EKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRK 106 + +++ K +K K K ++ ++ + EE+E+ ++ KE R + Sbjct: 131 VEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDES 190 Query: 107 EEEEEKKKKRRRKTKKK 123 +E + +K +++ K K Sbjct: 191 DEFLQSRKGQKKNQKNK 207 Score = 45.1 bits (105), Expect = 1e-05 Identities = 27/123 (21%), Positives = 61/123 (49%), Gaps = 3/123 (2%) Query: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 K KK K + +++ + + EE+E K K KE+ + + E+++ + + +K Sbjct: 145 KLPKKAKGKAQKSNKKWDGSEEDEDNSK---KIKERSRINSSGESGDESDEFLQSRKGQK 201 Query: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120 K ++ + E E+++ + + ++K E + R++KK+ K + + K+K +T Sbjct: 202 KNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELET 261 Query: 121 KKK 123 KK Sbjct: 262 GKK 264 Score = 40.0 bits (92), Expect = 4e-04 Identities = 39/156 (25%), Positives = 66/156 (42%), Gaps = 41/156 (26%) Query: 1 KKKKKKKKETEETEETEE-----TEEEEEKEGK----------------RKEKRKEKRKE 39 K+++KK+KE E E ++ T+ + E + K+ +KR Sbjct: 386 KRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPI 445 Query: 40 KEKKKKTKETEKRKEKEEEEKKR--------KRKRKKKKEEEEREEEEEEEEEE------ 85 E KK+ K ++ + KE E ++ +K+E E EEEE+ E Sbjct: 446 YEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDD 505 Query: 86 ------KEEEEKEEGRRRKKKKKRRRKEEEEEKKKK 115 EE EK EG + + K +EEEEE++++ Sbjct: 506 WEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEE 541 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.280 0.108 0.245 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 7,091,867 Number of Sequences: 37866 Number of extensions: 652298 Number of successful extensions: 165086 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 3942 Number of HSP's successfully gapped in prelim test: 382 Number of HSP's that attempted gapping in prelim test: 3865 Number of HSP's gapped (non-prelim): 67237 length of query: 123 length of database: 18,247,518 effective HSP length: 89 effective length of query: 34 effective length of database: 14,877,444 effective search space: 505833096 effective search space used: 505833096 T: 11 A: 40 X1: 18 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 46 (21.8 bits) S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.