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Search of human proteins with 23943928
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|23943928 hypothetical protein LOC140680 [Homo sapiens]
(363 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|23943928 hypothetical protein LOC140680 [Homo sapiens] 719 0.0
gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 55 1e-07
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 54 2e-07
gi|71061468 centromere protein E [Homo sapiens] 54 3e-07
gi|30089940 Golgi autoantigen, golgin subfamily a, 3 [Homo sapiens] 54 3e-07
gi|28460688 taxilin [Homo sapiens] 53 5e-07
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 52 6e-07
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 52 8e-07
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 52 8e-07
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 52 1e-06
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 52 1e-06
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 52 1e-06
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 52 1e-06
gi|8922940 gamma-taxilin [Homo sapiens] 51 1e-06
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 50 2e-06
gi|34878904 synaptonemal complex protein 1 [Homo sapiens] 50 4e-06
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 50 4e-06
gi|21735548 centrosomal protein 2 [Homo sapiens] 49 5e-06
gi|81295809 pericentrin [Homo sapiens] 49 5e-06
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 49 7e-06
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 49 9e-06
gi|148277064 cut-like homeobox 1 isoform a [Homo sapiens] 48 1e-05
gi|31652236 cut-like homeobox 1 isoform b [Homo sapiens] 48 1e-05
gi|55770834 centromere protein F [Homo sapiens] 48 1e-05
gi|50083279 centrosome protein 4 [Homo sapiens] 47 2e-05
gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens] 47 2e-05
gi|31652238 cut-like homeobox 1 isoform c [Homo sapiens] 47 3e-05
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 47 3e-05
gi|237858621 polyamine modulated factor 1 binding protein 1 isof... 47 3e-05
gi|237858619 polyamine modulated factor 1 binding protein 1 isof... 47 3e-05
>gi|23943928 hypothetical protein LOC140680 [Homo sapiens]
Length = 363
Score = 719 bits (1856), Expect = 0.0
Identities = 363/363 (100%), Positives = 363/363 (100%)
Query: 1 MAHVLQKPKHSGTHSIVQEFQVPDYVPWQQSKQETKPSTLPPVQQANSLHTSKMKTLTRV 60
MAHVLQKPKHSGTHSIVQEFQVPDYVPWQQSKQETKPSTLPPVQQANSLHTSKMKTLTRV
Sbjct: 1 MAHVLQKPKHSGTHSIVQEFQVPDYVPWQQSKQETKPSTLPPVQQANSLHTSKMKTLTRV 60
Query: 61 QPVFHFKPTTVVTSCQPKNPRELHRRRKLDPGKMHAKIWLMKTSLRSGRAALRELRSREN 120
QPVFHFKPTTVVTSCQPKNPRELHRRRKLDPGKMHAKIWLMKTSLRSGRAALRELRSREN
Sbjct: 61 QPVFHFKPTTVVTSCQPKNPRELHRRRKLDPGKMHAKIWLMKTSLRSGRAALRELRSREN 120
Query: 121 FLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRLQQLKSELQEWE 180
FLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRLQQLKSELQEWE
Sbjct: 121 FLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRLQQLKSELQEWE 180
Query: 181 EKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQISTLMRQLQQVKDSQ 240
EKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQISTLMRQLQQVKDSQ
Sbjct: 181 EKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQISTLMRQLQQVKDSQ 240
Query: 241 QDELDDLGEMRRKVLESLSDKIQKKKKKILSSVVAETQRPYEEALLQKMWESQDFLKCMQ 300
QDELDDLGEMRRKVLESLSDKIQKKKKKILSSVVAETQRPYEEALLQKMWESQDFLKCMQ
Sbjct: 241 QDELDDLGEMRRKVLESLSDKIQKKKKKILSSVVAETQRPYEEALLQKMWESQDFLKCMQ 300
Query: 301 RFREFIDQFEENMPVLRAEVEELQAQTREPREVIFEDVLLRRPKCTPDMDVILNIPVEEP 360
RFREFIDQFEENMPVLRAEVEELQAQTREPREVIFEDVLLRRPKCTPDMDVILNIPVEEP
Sbjct: 301 RFREFIDQFEENMPVLRAEVEELQAQTREPREVIFEDVLLRRPKCTPDMDVILNIPVEEP 360
Query: 361 LPF 363
LPF
Sbjct: 361 LPF 363
>gi|114155142 nuclear pore complex-associated protein TPR [Homo
sapiens]
Length = 2363
Score = 55.1 bits (131), Expect = 1e-07
Identities = 57/250 (22%), Positives = 116/250 (46%), Gaps = 47/250 (18%)
Query: 114 ELRSRENFLSKLNRELIETIQEMENSTTLHVRA---LLQQQDTLATIIDIL--------- 161
E+ R L+ +L++T ++++ T LH+ L Q +AT+ L
Sbjct: 858 EVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKEIATLKQHLSNMEVQVAS 917
Query: 162 ---------EYSNKKRLQQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLS 212
+ SNK+ + L S+L++ EE+ ++ L+++ + + +E+ Q V L
Sbjct: 918 QSSQRTGKGQPSNKEDVDDLVSQLRQTEEQ----VNDLKERLKTSTSNVEQYQAMVTSLE 973
Query: 213 TYMDHEYSI-----KSVQI---------STLMRQLQQVKDSQQDELDDLGEMRRKVLESL 258
++ E + K++++ + L ++L +V+ +Q+ DD +R+ +ES+
Sbjct: 974 ESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDD----KRRAIESM 1029
Query: 259 SDKIQKKKKKILSSVVAETQRPYEEALLQKMWESQDFLKCMQRFR---EFIDQFEENMPV 315
++ + KK LSSV E Q + A E Q C ++ + E +++E + +
Sbjct: 1030 EQQL-SELKKTLSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELML 1088
Query: 316 LRAEVEELQA 325
A+VE LQA
Sbjct: 1089 HAADVEALQA 1098
Score = 45.1 bits (105), Expect = 1e-04
Identities = 53/255 (20%), Positives = 116/255 (45%), Gaps = 42/255 (16%)
Query: 103 TSLRSGRAALRELRSRENFL----SKLNRELIETIQEMENSTTLHVRALLQQQDTLATII 158
T+L + + A R+ + + +K REL+ ++E ++A +Q +A++
Sbjct: 1056 TALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEA-----LQAAKEQVSKMASVR 1110
Query: 159 DILEYSNKKRLQQLKSELQEWEEKKK----------CKMSYLEQQAEQLNAKIEKTQEEV 208
LE + +K QL WEE+++ C+ LE+Q L+ +IEK ++V
Sbjct: 1111 QHLEETTQKAESQLLECKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKLSDKV 1170
Query: 209 ---------NFLSTYMDHEYSIKSVQISTLMRQLQQVKDSQQDELD----------DLGE 249
L+ + E + QI ++R +++ K+ + + E
Sbjct: 1171 VASVKEGVQGPLNVSLSEEGKSQE-QILEILRFIRREKEIAETRFEVAQVESLRYRQRVE 1229
Query: 250 MRRKVLESLSDKIQKKKKKILSSVVAETQRPYEEALLQKMWESQDFLKCMQRFREFIDQF 309
+ + L+ L D + +++K+ V A+T +EE L++K ++ + RE ++
Sbjct: 1230 LLERELQELQDSLNAEREKV--QVTAKTMAQHEE-LMKKTETMNVVMETNKMLREEKERL 1286
Query: 310 EENMPVLRAEVEELQ 324
E+++ ++A+V +L+
Sbjct: 1287 EQDLQQMQAKVRKLE 1301
Score = 37.0 bits (84), Expect = 0.028
Identities = 45/197 (22%), Positives = 80/197 (40%), Gaps = 31/197 (15%)
Query: 53 KMKTLTRVQPVFH-FKPTTVVTSCQPKNPRELHRRRKLDPGKMHAKIWLMKTSLRSGRAA 111
K+KT+T+V+ + +K Q E + D + H + M+ + A
Sbjct: 1427 KVKTITQVKKIGRRYKTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQELKETLNQA 1486
Query: 112 LRELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRLQQ 171
+ +S E+ + L + L E E N LQ+Q Q
Sbjct: 1487 ETKSKSLESQVENLQKTLSEKETEARN---------LQEQTV-----------------Q 1520
Query: 172 LKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQISTLMR 231
L+SEL + + + + EQ +Q+ K EKT++ + + + H +K Q++
Sbjct: 1521 LQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIAHLAGVKD-QLTKENE 1579
Query: 232 QLQQ---VKDSQQDELD 245
+L+Q D Q+DELD
Sbjct: 1580 ELKQRNGALDQQKDELD 1596
Score = 36.6 bits (83), Expect = 0.036
Identities = 52/257 (20%), Positives = 96/257 (37%), Gaps = 47/257 (18%)
Query: 113 RELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRLQQL 172
RE +S L KLN +L ++ + R + Q T K+ L+
Sbjct: 73 RECQSLRLELEKLNNQLKALTEKNKELEIAQDRNIAIQSQFTRT---------KEELEAE 123
Query: 173 KSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQISTLMRQ 232
K +L E+ ++ YL + ++LN K++++ L +D E V + ++
Sbjct: 124 KRDLIRTNERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLD-ELQASDVSVKYREKR 182
Query: 233 LQQVKD--------------SQQDELDDLGEMRRKVLESLSDKIQKKKKKILS------- 271
L+Q K+ ++ DEL LG + + L ++ KK+++
Sbjct: 183 LEQEKELLHSQNTWLNTELKTKTDELLALGREKGNEILELKCNLENKKEEVSRLEEQMNG 242
Query: 272 -SVVAETQRPYEEALLQKMWESQD---------------FLKCMQRFREFIDQFEENMPV 315
E + + E LL K+ E+++ +K ++ D E
Sbjct: 243 LKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNE 302
Query: 316 LRAEVEELQAQTREPRE 332
L VEEL +E E
Sbjct: 303 LTRAVEELHKLLKEAGE 319
Score = 36.6 bits (83), Expect = 0.036
Identities = 43/250 (17%), Positives = 101/250 (40%), Gaps = 20/250 (8%)
Query: 124 KLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRLQQLKSELQEWEEKK 183
++N+ L E ++E+E + ++ ++ + + L ++ +++++ LQE +K
Sbjct: 418 RINKYLDEIVKEVEAKAPI-LKRQREEYERAQKAVASLSVKLEQAMKEIQ-RLQEDTDKA 475
Query: 184 KCKMSYLEQQAEQLNAKIEKTQEEVNFL--------STYMDHEYSIKSVQISTLMRQLQQ 235
+ S LE+ ++ +++ +++ L ++ + + S IS+ + Q
Sbjct: 476 NKQSSVLERDNRRMEIQVKDLSQQIRVLLMELEEARGNHVIRDEEVSSADISSSSEVISQ 535
Query: 236 --VKDSQQDELDDLGEMRRKVLESLSDKIQKKKKKILSSVVAETQRPYEEALLQKMWESQ 293
V +EL + L L + ++++++ SS + E Q E AL E +
Sbjct: 536 HLVSYRNIEELQQQNQRLLVALRELGETREREEQETTSSKITELQLKLESALT----ELE 591
Query: 294 DFLKCMQRFREFIDQFEENMPVLRAEVEELQAQTREPREVIFEDVLL----RRPKCTPDM 349
K Q + +D + R + + +DV L +RP + +
Sbjct: 592 QLRKSRQHQMQLVDSIVRQRDMYRILLSQTTGVAIPLHASSLDDVSLASTPKRPSTSQTV 651
Query: 350 DVILNIPVEE 359
+PV E
Sbjct: 652 STPAPVPVIE 661
Score = 35.4 bits (80), Expect = 0.080
Identities = 55/269 (20%), Positives = 111/269 (41%), Gaps = 62/269 (23%)
Query: 115 LRSRENFLSKLNRELIETI---QEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRLQQ 171
L+ F ++L ++L+E QE+++ + ++ QQ L KK L
Sbjct: 994 LKESAEFQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSEL-----------KKTLSS 1042
Query: 172 LKSELQEWEEKKKCKMSYLEQQAE---QLNAKIEKTQEEVNFLSTYMDHEYSIKSVQ--- 225
+++E+QE ++ +S EQQA Q AKI + + + M H ++++Q
Sbjct: 1043 VQNEVQEALQRASTALSN-EQQARRDCQEQAKI-AVEAQNKYERELMLHAADVEALQAAK 1100
Query: 226 --------ISTLMRQLQQVKDSQQDELDDLGEMRRKVLES------------------LS 259
+ + + Q +SQ E E R ++L+ L
Sbjct: 1101 EQVSKMASVRQHLEETTQKAESQLLECKASWEERERMLKDEVSKCVCRCEDLEKQNRLLH 1160
Query: 260 DKIQKKKKKILSSVVAETQRPYEEALLQKMWESQ---DFLKCMQRFREFID--------- 307
D+I+K K+++SV Q P +L ++ + + L+ ++R +E +
Sbjct: 1161 DQIEKLSDKVVASVKEGVQGPLNVSLSEEGKSQEQILEILRFIRREKEIAETRFEVAQVE 1220
Query: 308 --QFEENMPVLRAEVEELQAQTREPREVI 334
++ + + +L E++ELQ RE +
Sbjct: 1221 SLRYRQRVELLERELQELQDSLNAEREKV 1249
Score = 33.1 bits (74), Expect = 0.40
Identities = 58/257 (22%), Positives = 112/257 (43%), Gaps = 57/257 (22%)
Query: 114 ELRSRENFLSKLNRE----LIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRL 169
EL+++ + L L RE ++E +EN V L +Q + L T SN+
Sbjct: 200 ELKTKTDELLALGREKGNEILELKCNLENKKE-EVSRLEEQMNGLKT-------SNEHLQ 251
Query: 170 QQLKSELQEWEEKKKCKMSYLEQQAEQLNAKI----------EKTQEEVNFLSTYMDHEY 219
+ ++ L + +E K+ + S E+ +LNA I + ++ + N L+ ++ +
Sbjct: 252 KHVEDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAVEELH 311
Query: 220 SI--------KSVQISTLMRQLQQVKDSQQDE-LDDLGEMRRKVLESLSDKIQKKKKK-- 268
+ K++Q L +++Q KD + E L+ +G + K LE+ +D + K+K
Sbjct: 312 KLLKEAGEANKAIQDHLL--EVEQSKDQMEKEMLEKIGRL-EKELENANDLLSATKRKGA 368
Query: 269 ILS-----------SVVAETQRP----------YEEALLQKMWESQDFLKCMQRFREFID 307
ILS + VA+ +P Y E Q + E + + + E +
Sbjct: 369 ILSEEELAAMSPTAAAVAKIVKPGMKLTELYNAYVETQDQLLLEKLENKRINKYLDEIVK 428
Query: 308 QFEENMPVLRAEVEELQ 324
+ E P+L+ + EE +
Sbjct: 429 EVEAKAPILKRQREEYE 445
Score = 30.4 bits (67), Expect = 2.6
Identities = 44/223 (19%), Positives = 94/223 (42%), Gaps = 33/223 (14%)
Query: 110 AALRELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRL 169
A + LR R+ + L REL QE+++S + T+A ++++ + +
Sbjct: 1217 AQVESLRYRQR-VELLEREL----QELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNV 1271
Query: 170 QQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQISTL 229
+++ EEK++ LEQ +Q+ AK+ K + ++ L + ++S
Sbjct: 1272 VMETNKMLR-EEKER-----LEQDLQQMQAKVRKLELDILPLQE--------ANAELSEK 1317
Query: 230 MRQLQQVKDSQQDELDDLGEMRRKVLESLSDKIQKKKKKILSSVVAETQRPYEEALLQKM 289
LQ K ++++ + ++ D ++ +K+LS T+R +Q++
Sbjct: 1318 SGMLQAEKKLLEEDVKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKR------IQQL 1371
Query: 290 WESQDFLKC--------MQRFREFIDQFEENMPVLRAEVEELQ 324
E LK + + I +E++ +R E E +Q
Sbjct: 1372 TEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQ 1414
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 54.3 bits (129), Expect = 2e-07
Identities = 57/246 (23%), Positives = 110/246 (44%), Gaps = 23/246 (9%)
Query: 110 AALRELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIID----ILEYSN 165
A+ +E RS L K+ E++ ++E + + D I + I E
Sbjct: 1473 ASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEK 1532
Query: 166 -KKRLQQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSV 224
KK+++Q KSELQ E+ + + + E KI + Q E+N + + +D + + K
Sbjct: 1533 IKKQVEQEKSELQAALEEAEASLEHEE-------GKILRIQLELNQVKSEVDRKIAEKDE 1585
Query: 225 QISTLMRQLQQVKDSQQDELD-------DLGEMRRKVLESLSD-KIQKKKKKILSSVVAE 276
+I + R ++ +S Q LD D +++K+ L++ +IQ +++
Sbjct: 1586 EIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALR 1645
Query: 277 TQRPYEEALLQKMWESQDFLKCMQRFREFIDQFEENMPVLRAEVEELQA---QTREPREV 333
R + L D L+ + +E + E +L+AE+EEL+A QT R++
Sbjct: 1646 NYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKI 1705
Query: 334 IFEDVL 339
+++L
Sbjct: 1706 AEQELL 1711
Score = 42.7 bits (99), Expect = 5e-04
Identities = 38/225 (16%), Positives = 96/225 (42%), Gaps = 15/225 (6%)
Query: 112 LRELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRLQQ 171
L + R N L EL T+++ E S + + LL + + + ++ L
Sbjct: 1675 LAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLL-----HTQNTSLIN 1729
Query: 172 LKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQISTLMR 231
K +L+ + + +M + Q+A K +K + ++ + E S + + +
Sbjct: 1730 TKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDT-SAHLERMKK 1788
Query: 232 QLQQVKDSQQDELDDLGEMRRKVLESLSDKIQKKKKKILSSVVAETQ---------RPYE 282
L+Q Q LD+ ++ K + K++ + +++ V +E + R +E
Sbjct: 1789 NLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHE 1848
Query: 283 EALLQKMWESQDFLKCMQRFREFIDQFEENMPVLRAEVEELQAQT 327
+ + +++++ K + R ++ +D+ + + + + EE + Q+
Sbjct: 1849 RKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQS 1893
Score = 35.0 bits (79), Expect = 0.10
Identities = 56/269 (20%), Positives = 109/269 (40%), Gaps = 50/269 (18%)
Query: 112 LRELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRLQQ 171
L E++++E +L +L ++ + + R L ++DTL + + + + +++++
Sbjct: 1260 LSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQL-DEKDTLVSQLSRGKQAFTQQIEE 1318
Query: 172 LKSELQEWEEKKKCKMSYL------------EQQAEQLNAKIE---------------KT 204
LK +L+E E K K +++ EQ E+ AK E +T
Sbjct: 1319 LKRQLEE-EIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRT 1377
Query: 205 QEEVNFLSTYMDHEYSIKSV------------QISTLMRQLQQVKDSQQDELDDL--GEM 250
+ E + + + E + K + ++ L++ K Q+E++DL
Sbjct: 1378 KYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVE 1437
Query: 251 RRKVLESLSDKIQKKKKKILS---SVVAETQRPYEEALLQKMWESQDFLKCMQRFREFID 307
R + DK Q+ KIL+ ET E + + S + K + E +D
Sbjct: 1438 RTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLD 1497
Query: 308 QFEENMPVLRAEVEELQAQTREPREVIFE 336
Q E L+ E + LQ + + E I E
Sbjct: 1498 QLE----TLKRENKNLQQEISDLTEQIAE 1522
Score = 30.8 bits (68), Expect = 2.0
Identities = 46/212 (21%), Positives = 95/212 (44%), Gaps = 37/212 (17%)
Query: 96 AKIWLMKTSLRSG-RAALRELRSRE---NFLSKLNRELIETIQEMENSTTLHVRALLQQQ 151
AK+ K +L+ + L +L++ E N L+K +L + + ++E S + + +
Sbjct: 994 AKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLE 1053
Query: 152 DTLATIIDILEYSNKKRL--QQLKSELQEWEEKKKCKMSYLEQQAE-------------- 195
+ L+ + + + + K +L E +KK+ +MS L+ + E
Sbjct: 1054 RAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIK 1113
Query: 196 QLNAKIEKTQEEVNFLSTYMDHEYSIKSVQISTLMRQLQQVKDSQQDELDDLGEMRRKVL 255
+L A+IE+ +EE I++ + S + Q+ S+ EL+++ E +
Sbjct: 1114 ELQARIEELEEE-------------IEAERASRAKAEKQRSDLSR--ELEEISERLEEAG 1158
Query: 256 ESLSDKIQKKKKKILSSVVAETQRPYEEALLQ 287
+ S +I+ KK+ + + +R EEA LQ
Sbjct: 1159 GATSAQIEMNKKR--EAEFQKMRRDLEEATLQ 1188
Score = 29.3 bits (64), Expect = 5.8
Identities = 28/174 (16%), Positives = 69/174 (39%), Gaps = 18/174 (10%)
Query: 167 KRLQQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQI 226
K LQ EL+E E ++ + E+Q L+ ++E+ E + + + +
Sbjct: 1113 KELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKRE 1172
Query: 227 STLMRQLQQVKDSQQDELDDLGEMRRKVLESLS------DKIQKKKKKILSSVVAETQRP 280
+ + + ++++ +R+K +S++ D +Q+ K+K+
Sbjct: 1173 AEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKL----------- 1221
Query: 281 YEEALLQKMWESQDFLKCMQRFREFIDQFEENMPVLRAEVEELQAQTREPREVI 334
E+ + E D M+ + E+ L ++ E++ + E + +I
Sbjct: 1222 -EKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLI 1274
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 53.5 bits (127), Expect = 3e-07
Identities = 54/240 (22%), Positives = 122/240 (50%), Gaps = 31/240 (12%)
Query: 105 LRSGRAALRELRSRENFLSKLNRELIETIQEMENSTTL---HVRALLQQQDTLATIIDIL 161
L+ + + ELR +S+ ++I T Q++E S T + L ++Q+ L + ++
Sbjct: 1244 LKEHQETIDELRRS---VSEKTAQIINT-QDLEKSHTKLQEEIPVLHEEQELLPNVKEVS 1299
Query: 162 EYSNKKRLQQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSI 221
E ++ + +L+ ++ K ++ +E + +LN K +++QEE+ L+ D+ +I
Sbjct: 1300 E--TQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTI 1357
Query: 222 KSVQISTLMRQLQQVKDSQQDELDDLGEMRRKVLESLSDKIQKKKKKILSSVVAETQ--R 279
K L + Q+K+ ++ L + E + K +SL+ K+K + +V+E + +
Sbjct: 1358 K----EALEVKHDQLKEHIRETLAKIQESQSKQEQSLN---MKEKDNETTKIVSEMEQFK 1410
Query: 280 PYEEALL----------QKMWESQDFLKCMQRFREFIDQFEENMPVLRAEVEELQAQTRE 329
P + ALL +++ ES D +K + + ++ + + +E VL++E ++L+ +E
Sbjct: 1411 PKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQE---VLQSESDQLKENIKE 1467
Score = 53.5 bits (127), Expect = 3e-07
Identities = 58/267 (21%), Positives = 123/267 (46%), Gaps = 44/267 (16%)
Query: 101 MKTSLRSGRAALRELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQ--QQDTLATII 158
+K +R A ++E +S++ LN ++E +N TT V + Q +D+ I
Sbjct: 1368 LKEHIRETLAKIQESQSKQE--QSLN------MKEKDNETTKIVSEMEQFKPKDSALLRI 1419
Query: 159 DILEYSNKKRLQQL----------KSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEV 208
+I KRLQ+ K +LQ +E + + L++ +++ AK +T+EE+
Sbjct: 1420 EIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEEL 1479
Query: 209 NFLSTYMDHE----------YSIKSVQISTLMRQLQQVKDSQQDELDDLGEMRR----KV 254
+ + S K +IST+ +QL+ + D Q+++ ++ E K
Sbjct: 1480 KVAHCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQ 1539
Query: 255 LESLSDKIQ-----KKKKKILSSVVAETQRPYEEALLQKMWESQDFLKCMQRFREFIDQF 309
+ + +K+ K+ +K S + + E L ++ ESQ+ ++ M + +E + +
Sbjct: 1540 ISEVQEKVNELKQFKEHRKAKDSALQSIESKMLE-LTNRLQESQEEIQIMIKEKEEMKRV 1598
Query: 310 EENMPV----LRAEVEELQAQTREPRE 332
+E + + L+ +E+ A+ +E +E
Sbjct: 1599 QEALQIERDQLKENTKEIVAKMKESQE 1625
Score = 49.3 bits (116), Expect = 5e-06
Identities = 51/242 (21%), Positives = 119/242 (49%), Gaps = 27/242 (11%)
Query: 113 RELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRLQQL 172
++++ + LSKL E + Q++ + ++++++++D L + + L K QL
Sbjct: 1854 KQIKDQSLTLSKLEIENLNLAQKLHENLE-EMKSVMKERDNLRRVEETL----KLERDQL 1908
Query: 173 KSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQISTLMRQ 232
K LQE K + ++Q+ + ++ +E V+ L + S K++QIS + +
Sbjct: 1909 KESLQE----TKARDLEIQQELKTARMLSKEHKETVDKLR----EKISEKTIQISDIQKD 1960
Query: 233 LQQVKDSQQDELDDLGEMRRKVL----------ESLSDKIQKKKKKILSSVVAETQRPYE 282
L + KD Q ++ +L + ++L + +++ Q KK+ ++ ++ R
Sbjct: 1961 LDKSKDELQKKIQELQKKELQLLRVKEDVNMSHKKINEMEQLKKQFEAQNLSMQSVRMDN 2020
Query: 283 EALLQKMWESQDFLKCMQRFREFIDQFEENMPVLR----AEVEELQAQTREPREVIFEDV 338
L +K+ ES + ++ + + R+ + + +E++ + R A + E+ A+ R+ +V E
Sbjct: 2021 FQLTKKLHESLEEIRIVAKERDELRRIKESLKMERDQFIATLREMIARDRQNHQVKPEKR 2080
Query: 339 LL 340
LL
Sbjct: 2081 LL 2082
Score = 41.2 bits (95), Expect = 0.001
Identities = 55/253 (21%), Positives = 107/253 (42%), Gaps = 26/253 (10%)
Query: 90 DPGKMHAKIWLMKTSLRSGRAALRELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQ 149
DP +M ++ +T + LRS L + +EL T ++MEN L+ L
Sbjct: 619 DPKQMKQTLFDAETVALDAKRESAFLRSENLELKEKMKELATTYKQMENDIQLYQSQLEA 678
Query: 150 QQDTLATIIDILEYSNKKRLQQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVN 209
++ ++ +K LQ +E+ + K+ +L KI Q+E+N
Sbjct: 679 KKK--------MQVDLEKELQSAFNEITKLTSLIDGKVPKDLLCNLELEGKITDLQKELN 730
Query: 210 FLSTYMDHEYSIKSVQISTLMRQLQQVKDSQQDELDDLGEMRRKVLESLSDK---IQKKK 266
K V+ + +R+ + + S+ L E RK ++ S++ I +K
Sbjct: 731 ------------KEVEENEALRE-EVILLSELKSLPSEVERLRKEIQDKSEELHIITSEK 777
Query: 267 KKILSSVVAETQRPYEEALLQKMWESQDFLKCMQRFREFIDQFEENMPVLRAEVEELQAQ 326
K+ S VV + R + LL+++ +++D L Q + DQ +N L + E+
Sbjct: 778 DKLFSEVVHKESR--VQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKM 835
Query: 327 TREPREVIFEDVL 339
E E + ++++
Sbjct: 836 VLEENERMNQEIV 848
Score = 41.2 bits (95), Expect = 0.001
Identities = 76/354 (21%), Positives = 149/354 (42%), Gaps = 65/354 (18%)
Query: 34 ETKPSTLPPVQQANSLHTSKMKTLTRVQPVFHFKPTTVVTSCQPKNPRELHRRRKLDPGK 93
E + STL V++ +L T K++ Q + K T + L R
Sbjct: 897 ENRDSTLQTVEREKTLITEKLQ-----QTLEEVKTLTQEKDDLKQLQESLQIERDQLKSD 951
Query: 94 MHAKIWLMKTSLRSGRAALRELRSRENFLSKLNRELIETIQE---MENSTT--------- 141
+H + + + R AL L+ + ++ L ++ E + ME +T
Sbjct: 952 IHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHMEENTGETKDEFQQK 1011
Query: 142 ---LHVRALLQQQDTLATIIDILEYSNKKRLQQLKSELQEWEEKKKCKMSYL---EQQAE 195
+ + L+ ++T D+ + ++ +++ S +QE E ++ S + EQ
Sbjct: 1012 MVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKT 1071
Query: 196 QLNAKIEKT---QEEVNFLSTYMDHEYSI----------KSVQIST-----------LMR 231
L IE T QEE+ L + + I K ++S L
Sbjct: 1072 DLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKE 1131
Query: 232 QLQQVKDSQQDEL---DDLGEMRRKV--LESLSDKIQKKKKKILSSVVAETQRPYEEALL 286
+ QQ+++ QQ L +++ EM++K+ +E+L +++ K K L+ ET+R L
Sbjct: 1132 KSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNEL---KNKELTLEHMETER---LELA 1185
Query: 287 QKMWESQDFLKCMQRFREFIDQ----FEENMPVLRAEVEELQA---QTREPREV 333
QK+ E+ + +K + + R+ + + FE LR + E++A QT+E ++
Sbjct: 1186 QKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKEELKI 1239
Score = 36.2 bits (82), Expect = 0.047
Identities = 44/217 (20%), Positives = 94/217 (43%), Gaps = 33/217 (15%)
Query: 115 LRSRENFLSKLNRELIETIQEMEN--STTLHVRALLQQQDTLATIIDILEYSNKKRLQQL 172
L+ + + KL + E E+ N H L+ QD + + + K Q+
Sbjct: 1730 LKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQET 1789
Query: 173 KSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQISTLMRQ 232
+L+ +K K+S +++ E NAK+++ +E+ Q+ TL +
Sbjct: 1790 IDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQEL-----------KANEHQLITLKK- 1837
Query: 233 LQQVKDSQQDELDDLGEMRRKVLESLSDKIQKKKKKILSSVVAETQRPYEEA-LLQKMWE 291
D+ E ++KV E +++ KK+I + ++ E L QK+ E
Sbjct: 1838 -------------DVNETQKKVSE-----MEQLKKQIKDQSLTLSKLEIENLNLAQKLHE 1879
Query: 292 SQDFLKCMQRFREFIDQFEENMPVLRAEVEELQAQTR 328
+ + +K + + R+ + + EE + + R +++E +T+
Sbjct: 1880 NLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETK 1916
Score = 35.4 bits (80), Expect = 0.080
Identities = 49/198 (24%), Positives = 86/198 (43%), Gaps = 37/198 (18%)
Query: 112 LRELRSRENFLSKLNRELIETIQEMENSTTLHV------RALLQQQDTL-ATIIDILEYS 164
L E+ ++ L+ T QE +N TLH+ + +L++ + + I+++ + +
Sbjct: 795 LEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEA 854
Query: 165 NK--KRLQQLKSEL----QEWEEKKKC---KMSYLEQQAEQLNAK--------------I 201
K L LK+EL QE +EK + +++ +EQ EQL +
Sbjct: 855 QKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLIT 914
Query: 202 EKTQEEVNFLSTYMDHEYSIKSVQISTLMRQLQQVKDSQQDELD---DLGEMRRKVLESL 258
EK Q+ + + T + +K +Q +L + Q+K D ++ D E R LESL
Sbjct: 915 EKLQQTLEEVKTLTQEKDDLKQLQ-ESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESL 973
Query: 259 ---SDKIQKKKKKILSSV 273
+ I K KI V
Sbjct: 974 KQHQETINTLKSKISEEV 991
>gi|30089940 Golgi autoantigen, golgin subfamily a, 3 [Homo sapiens]
Length = 1498
Score = 53.5 bits (127), Expect = 3e-07
Identities = 52/232 (22%), Positives = 115/232 (49%), Gaps = 33/232 (14%)
Query: 114 ELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRL---- 169
E R+ E LS+L+RE+ + Q M + H+++ +++D + T + L++ ++ +
Sbjct: 893 EKRTAEAELSRLHREVAQVRQHMADLEG-HLQSAQKERDEMETHLQSLQFDKEQMVAVTE 951
Query: 170 --QQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQIS 227
+ LK +++E +++ + ++ +Q+ +L + + Q+E M ++ +
Sbjct: 952 ANEALKKQIEELQQEARKAITEQKQKMRRLGSDLTSAQKE-------MKTKHKAYENAVG 1004
Query: 228 TLMRQLQQVKDSQQDELDDLGEMRRKVLES-----LSDKIQKKK-------------KKI 269
L R+LQ+ +++ +LG++R + S L ++IQ + +K
Sbjct: 1005 ILSRRLQEALAAKEAADAELGQLRAQGGSSDSSLALHERIQALEAELQAVSHSKTLLEKE 1064
Query: 270 LSSVVAETQRPYEEALLQKMWESQDFLKCMQRFREFIDQFEENMPVLRAEVE 321
L V+A T + EE+ +K+ E +D L+ + FR+ I + EE+ L E+E
Sbjct: 1065 LQEVIALTSQELEESR-EKVLELEDELQESRGFRKKIKRLEESNKKLALELE 1115
Score = 35.8 bits (81), Expect = 0.062
Identities = 50/240 (20%), Positives = 106/240 (44%), Gaps = 34/240 (14%)
Query: 113 RELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKR---L 169
R R + L + N++L ++ + T L Q L ILE + KR L
Sbjct: 1094 RGFRKKIKRLEESNKKLALELEHEKGKLT----GLGQSNAALREHNSILETALAKREADL 1149
Query: 170 QQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFL----------STYMDHEY 219
QL ++Q ++K+ + ++ + L A +EK +E+VN L + + +
Sbjct: 1150 VQLNLQVQAVLQRKEEEDRQMKHLVQALQASLEKEKEKVNSLKEQVAAAKVEAGHNRRHF 1209
Query: 220 SIKSVQISTLMRQLQ---QVKDSQQDELDDL----GEMRRKVLESLSDKIQKKKKKILSS 272
S+++S + ++LQ + Q E DDL G+ +++ + ++ + + + L
Sbjct: 1210 KAASLELSEVKKELQAKEHLVQKLQAEADDLQIREGKHSQEIAQFQAELAEARAQLQL-- 1267
Query: 273 VVAETQRPYEEALLQKMWESQDFLKCMQRFREFIDQFEENMPVLRAEVEELQAQTREPRE 332
Q+ +E L ++ +Q+ M+ + +DQ E + L+ +++ + Q R+ E
Sbjct: 1268 ----LQKQLDEQLSKQPVGNQE----MENLKWEVDQKEREIQSLKQQLDLTEQQGRKELE 1319
Score = 33.1 bits (74), Expect = 0.40
Identities = 56/256 (21%), Positives = 113/256 (44%), Gaps = 60/256 (23%)
Query: 115 LRSRENFLSKLNR---ELIETIQEMENSTTLHVRALLQQQDTLATIID---ILEYSNKKR 168
L+SRE L L EL + E++ ++DT+ + + ILE +
Sbjct: 733 LQSREQSLDALQTHYDELQARLGELQGEAA-------SREDTICLLQNEKIILEAA---- 781
Query: 169 LQQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQIST 228
LQ KS +E + + LE+ E+ + +EK +EE+ S ++H + +
Sbjct: 782 LQAAKSGKEELDRGAR----RLEEGTEETSETLEKLREELAIKSGQVEH----LQQETAA 833
Query: 229 LMRQLQQVKD----------------SQQDELDDLGEMRRKVLESLSDKIQKKKKKI--- 269
L +Q+Q++K+ + +D+L + RK L+S +++++ ++
Sbjct: 834 LKKQMQKIKEQFLQQKVMVEAYRRDATSKDQLISELKATRKRLDSELKELRQELMQVHGE 893
Query: 270 LSSVVAETQRPYEEA--LLQKMWESQDFLKCMQRFREFID------QFEENMPV------ 315
+ AE R + E + Q M + + L+ Q+ R+ ++ QF++ V
Sbjct: 894 KRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKERDEMETHLQSLQFDKEQMVAVTEAN 953
Query: 316 --LRAEVEELQAQTRE 329
L+ ++EELQ + R+
Sbjct: 954 EALKKQIEELQQEARK 969
Score = 32.0 bits (71), Expect = 0.89
Identities = 32/170 (18%), Positives = 79/170 (46%), Gaps = 12/170 (7%)
Query: 149 QQQDTLATIIDILEYSNKKRLQQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEV 208
Q+ + L +D ++ +Q LK +L E++ + ++ L+Q + + +++E QE++
Sbjct: 1284 QEMENLKWEVD----QKEREIQSLKQQLDLTEQQGRKELEGLQQLLQNVKSELEMAQEDL 1339
Query: 209 NFLST---YMDHEYSIKSVQISTLMRQLQQVK-DSQQDELDDLGEMRRKVLES-LSDKIQ 263
+ + + S + TL++Q QQ+K D ++ E + + S + I+
Sbjct: 1340 SMTQKDKFMLQAKVSELKNNMKTLLQQNQQLKLDLRRGAAKTRKEPKGEASSSNPATPIK 1399
Query: 264 KKKKKILSSVVAETQRPYEEALLQKMWESQDFLKCMQRFREFIDQFEENM 313
+ +S++ E RP + + ++ C+Q+ ++ +D + M
Sbjct: 1400 IPDCPVPASLLEELLRPPPAVSKEPL---KNLNSCLQQLKQEMDSLQRQM 1446
>gi|28460688 taxilin [Homo sapiens]
Length = 546
Score = 52.8 bits (125), Expect = 5e-07
Identities = 51/240 (21%), Positives = 111/240 (46%), Gaps = 16/240 (6%)
Query: 112 LRELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRLQQ 171
L E R+ + + L ++ + +QE ++ H +A+L + L ++ L+ N+ ++
Sbjct: 200 LEEHRNSQKQMKLLQKKQSQLVQEKDHLRGEHSKAVLARSK-LESLCRELQRHNRSLKEE 258
Query: 172 LKSELQEWEEKKKCKMSY-------LEQQAEQLNAKIEKTQEEVNFLSTYMD---HEYSI 221
+E EEK+K S+ ++ Q EQ N + K ++E L+ + +Y +
Sbjct: 259 GVQRAREEEEKRKEVTSHFQVTLNDIQLQMEQHNERNSKLRQENMELAERLKKLIEQYEL 318
Query: 222 KSVQISTLMRQLQQVKDSQQDELDDLGEMRRKVLESLSDKIQKKKKKILSSVVAETQRPY 281
+ I + + KD QQ +D + +++L+ ++ Q++K +L V E+QR
Sbjct: 319 REEHIDKVFKH----KDLQQQLVDAKLQQAQEMLKEAEERHQREKDFLLKEAV-ESQRMC 373
Query: 282 EEALLQKMWESQDFLKCMQRFREFIDQFEENMPVLRAEVEELQAQTREPREVIFEDVLLR 341
E Q+ Q ++F EF + ++ V +E++ T++ +++ E + R
Sbjct: 374 ELMKQQETHLKQQLALYTEKFEEFQNTLSKSSEVFTTFKQEMEKMTKKIKKLEKETTMYR 433
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 52.4 bits (124), Expect = 6e-07
Identities = 64/251 (25%), Positives = 113/251 (45%), Gaps = 33/251 (13%)
Query: 110 AALRELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEY--SNKK 167
A+L+E RS L KL E + ++E T L+Q+ I D+ E N K
Sbjct: 1470 ASLKESRSLSTELFKLKNAYEEALDQLE--TVKRENKNLEQE-----IADLTEQIAENGK 1522
Query: 168 RLQQLKSELQEWE-EKKKCKMSYLEQQA--EQLNAKIEKTQEEVNFLSTYMDHEYSIKSV 224
+ +L+ ++ E EK +++ E +A E AKI + Q E+ + + +D + + K
Sbjct: 1523 TIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDE 1582
Query: 225 QISTLMRQLQQVKDSQQDELDDLGEMRRKVLESLSDKIQKKKKKILSSV----------V 274
+I L R Q+ ++ Q LD R + + +++KK + L+ +
Sbjct: 1583 EIEQLKRNYQRTVETMQSALDAEVRSRNEAI-----RLKKKMEGDLNEIEIQLSHANRQA 1637
Query: 275 AETQ---RPYEEALLQKMWESQDFLKCMQRFREFIDQFEENMPVLRAEVEELQA---QTR 328
AET R + L D L+ + +E + E +L+AEVEEL+A QT
Sbjct: 1638 AETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTE 1697
Query: 329 EPREVIFEDVL 339
R++ +++L
Sbjct: 1698 RARKLAEQELL 1708
Score = 39.7 bits (91), Expect = 0.004
Identities = 53/261 (20%), Positives = 110/261 (42%), Gaps = 33/261 (12%)
Query: 101 MKTSLRSGRAALR-------ELRSRENFLSKLNRELIETIQEMEN------STTLHVRAL 147
+ +RS A+R +L E LS NR+ ET++ + + T LH+
Sbjct: 1602 LDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDA 1661
Query: 148 LQQQDTLATIIDILEYSNKKRLQQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEE 207
L+ Q+ L + I+E +R L++E++E + + E+ + ++ + E
Sbjct: 1662 LRGQEDLKEQLAIVE----RRANLLQAEVEEL----RATLEQTERARKLAEQELLDSNER 1713
Query: 208 VNFLSTYMDHEYSIKSVQISTLMRQLQQVKDSQQDELDDLGEMRRKVLES--LSDKIQKK 265
V L T K + LM+ +V+D+ +D + + ++ + ++ ++++++K+
Sbjct: 1714 VQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKE 1773
Query: 266 K---------KKILSSVVAETQRPYEEA-LLQKMWESQDFLKCMQRFREFIDQFEENMPV 315
+ KK L V + Q +EA L + K R RE + E
Sbjct: 1774 QDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKK 1833
Query: 316 LRAEVEELQAQTREPREVIFE 336
V+ L+ R +E+ ++
Sbjct: 1834 NTESVKGLRKYERRVKELTYQ 1854
Score = 37.7 bits (86), Expect = 0.016
Identities = 50/229 (21%), Positives = 96/229 (41%), Gaps = 26/229 (11%)
Query: 114 ELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRLQ--- 170
EL+ + +K L +Q + L ++Q+ A + L +N + Q
Sbjct: 1315 ELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRT 1374
Query: 171 -------QLKSELQEWEEKKKCKMSYLEQQAEQLNAK---IEKTQEEVNFLSTYMDHEYS 220
Q EL+E ++K ++ E+Q E +NAK +EKT++ + +
Sbjct: 1375 KYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRL---------QGE 1425
Query: 221 IKSVQIST-LMRQLQQVKDSQQDELDD-LGEMRRKVLESLSD-KIQKKKKKILSSVVAET 277
++ + + L D +Q D L E + K ES ++ + K+ + LS+ + +
Sbjct: 1426 VEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKL 1485
Query: 278 QRPYEEALLQKMWESQDFLKCMQRFREFIDQFEENMPVLRAEVEELQAQ 326
+ YEEAL Q ++ Q + +Q EN + E+E+ + Q
Sbjct: 1486 KNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIH-ELEKSRKQ 1533
Score = 37.0 bits (84), Expect = 0.028
Identities = 55/270 (20%), Positives = 111/270 (41%), Gaps = 57/270 (21%)
Query: 114 ELRSRENFLSKLNRELIETIQEMENSTTLHVRA----LLQQQDTL-----------ATII 158
EL E +L +L+ +QE +N L V+A LL ++ A I
Sbjct: 863 ELAKSEAKRKELEEKLVTLVQE-KNDLQLQVQAESENLLDAEERCDQLIKAKFQLEAKIK 921
Query: 159 DILEYSNKKRLQQLKSELQEWEEKKKCKMSYLEQQAEQLN---AKIEKTQEEVNFLSTYM 215
++ E + + +++ +EL + K + + S L++ + L AK+EK + +
Sbjct: 922 EVTERAEDE--EEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNL 979
Query: 216 DHEYSIKSVQISTLMRQLQQVKDSQQDELDDLGEMRRKV-------------LESLSDKI 262
E S I+ L R+ + ++++ Q LDDL KV +E L +
Sbjct: 980 TEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSL 1039
Query: 263 QKKKK----------------KILSSVVAETQRPYEEALLQKMWESQDFLKCMQRFREFI 306
+++KK K+ + + + ++ L + + +DF C + +
Sbjct: 1040 EQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQ--LDERLKKKDFEYCQLQSKVED 1097
Query: 307 DQ-----FEENMPVLRAEVEELQAQTREPR 331
+Q F++ + L+A +EEL+ + R
Sbjct: 1098 EQTLGLQFQKKIKELQARIEELEEEIEAER 1127
Score = 32.0 bits (71), Expect = 0.89
Identities = 72/314 (22%), Positives = 129/314 (41%), Gaps = 65/314 (20%)
Query: 86 RRKLDPGKMHAKIWL--MKTSLRS---GRAALREL-RSRENFLSKL---NRELIETIQEM 136
++KL+ K K+ + + +S+ S +A L ++ R+ E+ LS+ N E+ ++ E+
Sbjct: 1215 KQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSEL 1274
Query: 137 ENSTT-LHVRA--LLQQQDTLATIIDILEYSNKKRLQQ---LKSELQEWEEKKKCKMSYL 190
+ L A L +Q + +I+ L S + QQ LK +L+E E K K +++
Sbjct: 1275 TTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEE-ENKAKNALAHA 1333
Query: 191 ------------EQQAEQLNAKIE---------------KTQEEVNFLSTYMDHEYSIKS 223
EQ E+ K E +T+ E + + + E + K
Sbjct: 1334 LQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKK 1393
Query: 224 V------------QISTLMRQLQQVKDSQQDELDDL--GEMRRKVLESLSDKIQKKKKKI 269
+ ++ L++ K Q E++DL R L + DK Q+ K+
Sbjct: 1394 LAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKV 1453
Query: 270 LS---SVVAETQRPYEEALLQKMWESQDFLKCMQRFREFIDQFE----ENMPVLRAEVEE 322
L+ + E+Q E +L + S + K + E +DQ E EN L E+ +
Sbjct: 1454 LAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKN-LEQEIAD 1512
Query: 323 LQAQTREPREVIFE 336
L Q E + I E
Sbjct: 1513 LTEQIAENGKTIHE 1526
Score = 31.2 bits (69), Expect = 1.5
Identities = 48/221 (21%), Positives = 100/221 (45%), Gaps = 55/221 (24%)
Query: 96 AKIWLMKTSLRSG-RAALRELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTL 154
AK+ K +L+ + AL +L++ E+ ++ LN+ + Q++E+ + + L+Q+ L
Sbjct: 991 AKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVED-----LESSLEQEKKL 1045
Query: 155 ATIIDILEYSNKKRLQ-----------QLKSELQEWEEK-KKCKMSYLEQQAE------- 195
++ NK++L+ L+++ Q+ +E+ KK Y + Q++
Sbjct: 1046 RVDLE----RNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTL 1101
Query: 196 ---------QLNAKIEKTQEEVNFLSTYMDHEYSIKSVQISTLMRQLQQVKDSQQDELDD 246
+L A+IE+ +EE+ + +T + +Q D + EL++
Sbjct: 1102 GLQFQKKIKELQARIEELEEEI--------------EAERATRAKTEKQRSDYAR-ELEE 1146
Query: 247 LGEMRRKVLESLSDKIQKKKKKILSSVVAETQRPYEEALLQ 287
L E + S +I+ KK+ + + +R EEA LQ
Sbjct: 1147 LSERLEEAGGVTSTQIELNKKR--EAEFLKLRRDLEEATLQ 1185
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 52.0 bits (123), Expect = 8e-07
Identities = 57/246 (23%), Positives = 109/246 (44%), Gaps = 23/246 (9%)
Query: 110 AALRELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIID----ILEYSN 165
A+ +E RS L K+ E++ ++E + + D I + I E
Sbjct: 1475 ASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEK 1534
Query: 166 -KKRLQQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSV 224
KK+++Q K ELQ E+ + + + E KI + Q E+N + + +D + + K
Sbjct: 1535 IKKQVEQEKCELQAALEEAEASLEHEE-------GKILRIQLELNQVKSEVDRKIAEKDE 1587
Query: 225 QISTLMRQLQQVKDSQQDELD-------DLGEMRRKVLESLSD-KIQKKKKKILSSVVAE 276
+I L R ++ +S Q LD D +++K+ L++ +IQ +++
Sbjct: 1588 EIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALR 1647
Query: 277 TQRPYEEALLQKMWESQDFLKCMQRFREFIDQFEENMPVLRAEVEELQA---QTREPREV 333
R + L D L+ + +E + E +L+AE+EEL+A QT R++
Sbjct: 1648 NYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKI 1707
Query: 334 IFEDVL 339
+++L
Sbjct: 1708 AEQELL 1713
Score = 35.8 bits (81), Expect = 0.062
Identities = 38/180 (21%), Positives = 84/180 (46%), Gaps = 23/180 (12%)
Query: 167 KRLQQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYM---DHEYSIKS 223
K+ + L EW K+KC E+ +A++E +Q+E L T + + Y
Sbjct: 1450 KKQRNFDKILAEW--KQKC---------EETHAELEASQKEARSLGTELFKIKNAYEESL 1498
Query: 224 VQISTLMRQLQQVKDSQQDELDDLGEMRRKV--LESLSDKIQKKKKKILSSV-VAETQRP 280
Q+ TL R+ + ++ D + + E +++ LE + +++++K ++ +++ AE
Sbjct: 1499 DQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLE 1558
Query: 281 YEEALLQKMWESQDFLKC-----MQRFREFIDQFEEN-MPVLRAEVEELQAQTREPREVI 334
+EE + ++ + +K + E IDQ + N + ++ + L A+ R + I
Sbjct: 1559 HEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAI 1618
Score = 33.1 bits (74), Expect = 0.40
Identities = 46/241 (19%), Positives = 100/241 (41%), Gaps = 36/241 (14%)
Query: 112 LRELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRLQ- 170
+ EL+ + K L +Q + L ++Q++ A + L +N + Q
Sbjct: 1318 IEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQW 1377
Query: 171 ---------QLKSELQEWEEKKKCKMSYLEQQAEQLNAK---IEKTQEEVNFLSTYMDHE 218
Q EL+E ++K ++ E+ E +NAK +EKT++ +
Sbjct: 1378 RTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRL---------- 1427
Query: 219 YSIKSVQISTLMRQLQQVK------DSQQDELDD-LGEMRRKVLESLSD-KIQKKKKKIL 270
++ LM +++ D +Q D L E ++K E+ ++ + +K+ + L
Sbjct: 1428 ----QNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSL 1483
Query: 271 SSVVAETQRPYEEALLQKMWESQDFLKCMQRFREFIDQFEENMPVLRAEVEELQAQTREP 330
+ + + + YEE+L Q ++ Q + +Q E + E+E+++ Q +
Sbjct: 1484 GTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIH-ELEKIKKQVEQE 1542
Query: 331 R 331
+
Sbjct: 1543 K 1543
Score = 29.6 bits (65), Expect = 4.4
Identities = 45/212 (21%), Positives = 95/212 (44%), Gaps = 37/212 (17%)
Query: 96 AKIWLMKTSLRSG-RAALRELRSRE---NFLSKLNRELIETIQEMENSTTLHVRALLQQQ 151
AK+ K +L+ + L +L++ E N L+K +L + + ++E S + + +
Sbjct: 996 AKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLE 1055
Query: 152 DTLATIIDILEYSNKK--RLQQLKSELQEWEEKKKCKMSYLEQQAE-------------- 195
+ L+ + + ++ K +L E +KK+ ++S L+ + E
Sbjct: 1056 RAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIK 1115
Query: 196 QLNAKIEKTQEEVNFLSTYMDHEYSIKSVQISTLMRQLQQVKDSQQDELDDLGEMRRKVL 255
+L A+IE+ +EE I++ + S + Q+ S+ EL+++ E +
Sbjct: 1116 ELQARIEELEEE-------------IEAERASRAKAEKQRSDLSR--ELEEISERLEEAG 1160
Query: 256 ESLSDKIQKKKKKILSSVVAETQRPYEEALLQ 287
+ S +I+ KK+ + + +R EEA LQ
Sbjct: 1161 GATSAQIEMNKKR--EAEFQKMRRDLEEATLQ 1190
Score = 28.9 bits (63), Expect = 7.5
Identities = 28/174 (16%), Positives = 70/174 (40%), Gaps = 18/174 (10%)
Query: 167 KRLQQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQI 226
K LQ EL+E E ++ + E+Q L+ ++E+ E + + + +
Sbjct: 1115 KELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKRE 1174
Query: 227 STLMRQLQQVKDSQQDELDDLGEMRRKVLESLS------DKIQKKKKKILSSVVAETQRP 280
+ + + ++++ +R+K +S++ D +Q+ K+K+
Sbjct: 1175 AEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKL----------- 1223
Query: 281 YEEALLQKMWESQDFLKCMQRFREFIDQFEENMPVLRAEVEELQAQTREPREVI 334
E+ + E D ++ + E+ L ++ EL+++ E + +I
Sbjct: 1224 -EKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLI 1276
Score = 28.5 bits (62), Expect = 9.8
Identities = 27/107 (25%), Positives = 44/107 (41%), Gaps = 12/107 (11%)
Query: 102 KTSLRSGRAALRELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDIL 161
K ++ A +REL K N E ++ +++ E V+ L Q +
Sbjct: 1815 KKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHER----RVKELTYQTEE-------- 1862
Query: 162 EYSNKKRLQQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEV 208
+ N RLQ L +LQ + K + E+Q+ AK K Q E+
Sbjct: 1863 DRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHEL 1909
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 52.0 bits (123), Expect = 8e-07
Identities = 57/246 (23%), Positives = 109/246 (44%), Gaps = 23/246 (9%)
Query: 110 AALRELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIID----ILEYSN 165
A+ +E RS L K+ E++ ++E + + D I + I E
Sbjct: 1475 ASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEK 1534
Query: 166 -KKRLQQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSV 224
KK+++Q K ELQ E+ + + + E KI + Q E+N + + +D + + K
Sbjct: 1535 IKKQVEQEKCELQAALEEAEASLEHEE-------GKILRIQLELNQVKSEVDRKIAEKDE 1587
Query: 225 QISTLMRQLQQVKDSQQDELD-------DLGEMRRKVLESLSD-KIQKKKKKILSSVVAE 276
+I L R ++ +S Q LD D +++K+ L++ +IQ +++
Sbjct: 1588 EIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALR 1647
Query: 277 TQRPYEEALLQKMWESQDFLKCMQRFREFIDQFEENMPVLRAEVEELQA---QTREPREV 333
R + L D L+ + +E + E +L+AE+EEL+A QT R++
Sbjct: 1648 NYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKI 1707
Query: 334 IFEDVL 339
+++L
Sbjct: 1708 AEQELL 1713
Score = 35.8 bits (81), Expect = 0.062
Identities = 38/180 (21%), Positives = 84/180 (46%), Gaps = 23/180 (12%)
Query: 167 KRLQQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYM---DHEYSIKS 223
K+ + L EW K+KC E+ +A++E +Q+E L T + + Y
Sbjct: 1450 KKQRNFDKILAEW--KQKC---------EETHAELEASQKEARSLGTELFKIKNAYEESL 1498
Query: 224 VQISTLMRQLQQVKDSQQDELDDLGEMRRKV--LESLSDKIQKKKKKILSSV-VAETQRP 280
Q+ TL R+ + ++ D + + E +++ LE + +++++K ++ +++ AE
Sbjct: 1499 DQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLE 1558
Query: 281 YEEALLQKMWESQDFLKC-----MQRFREFIDQFEEN-MPVLRAEVEELQAQTREPREVI 334
+EE + ++ + +K + E IDQ + N + ++ + L A+ R + I
Sbjct: 1559 HEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAI 1618
Score = 33.1 bits (74), Expect = 0.40
Identities = 46/241 (19%), Positives = 100/241 (41%), Gaps = 36/241 (14%)
Query: 112 LRELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRLQ- 170
+ EL+ + K L +Q + L ++Q++ A + L +N + Q
Sbjct: 1318 IEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQW 1377
Query: 171 ---------QLKSELQEWEEKKKCKMSYLEQQAEQLNAK---IEKTQEEVNFLSTYMDHE 218
Q EL+E ++K ++ E+ E +NAK +EKT++ +
Sbjct: 1378 RTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRL---------- 1427
Query: 219 YSIKSVQISTLMRQLQQVK------DSQQDELDD-LGEMRRKVLESLSD-KIQKKKKKIL 270
++ LM +++ D +Q D L E ++K E+ ++ + +K+ + L
Sbjct: 1428 ----QNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSL 1483
Query: 271 SSVVAETQRPYEEALLQKMWESQDFLKCMQRFREFIDQFEENMPVLRAEVEELQAQTREP 330
+ + + + YEE+L Q ++ Q + +Q E + E+E+++ Q +
Sbjct: 1484 GTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIH-ELEKIKKQVEQE 1542
Query: 331 R 331
+
Sbjct: 1543 K 1543
Score = 29.6 bits (65), Expect = 4.4
Identities = 45/212 (21%), Positives = 95/212 (44%), Gaps = 37/212 (17%)
Query: 96 AKIWLMKTSLRSG-RAALRELRSRE---NFLSKLNRELIETIQEMENSTTLHVRALLQQQ 151
AK+ K +L+ + L +L++ E N L+K +L + + ++E S + + +
Sbjct: 996 AKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLE 1055
Query: 152 DTLATIIDILEYSNKK--RLQQLKSELQEWEEKKKCKMSYLEQQAE-------------- 195
+ L+ + + ++ K +L E +KK+ ++S L+ + E
Sbjct: 1056 RAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIK 1115
Query: 196 QLNAKIEKTQEEVNFLSTYMDHEYSIKSVQISTLMRQLQQVKDSQQDELDDLGEMRRKVL 255
+L A+IE+ +EE I++ + S + Q+ S+ EL+++ E +
Sbjct: 1116 ELQARIEELEEE-------------IEAERASRAKAEKQRSDLSR--ELEEISERLEEAG 1160
Query: 256 ESLSDKIQKKKKKILSSVVAETQRPYEEALLQ 287
+ S +I+ KK+ + + +R EEA LQ
Sbjct: 1161 GATSAQIEMNKKR--EAEFQKMRRDLEEATLQ 1190
Score = 28.9 bits (63), Expect = 7.5
Identities = 28/174 (16%), Positives = 70/174 (40%), Gaps = 18/174 (10%)
Query: 167 KRLQQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQI 226
K LQ EL+E E ++ + E+Q L+ ++E+ E + + + +
Sbjct: 1115 KELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKRE 1174
Query: 227 STLMRQLQQVKDSQQDELDDLGEMRRKVLESLS------DKIQKKKKKILSSVVAETQRP 280
+ + + ++++ +R+K +S++ D +Q+ K+K+
Sbjct: 1175 AEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKL----------- 1223
Query: 281 YEEALLQKMWESQDFLKCMQRFREFIDQFEENMPVLRAEVEELQAQTREPREVI 334
E+ + E D ++ + E+ L ++ EL+++ E + +I
Sbjct: 1224 -EKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLI 1276
Score = 28.5 bits (62), Expect = 9.8
Identities = 27/107 (25%), Positives = 44/107 (41%), Gaps = 12/107 (11%)
Query: 102 KTSLRSGRAALRELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDIL 161
K ++ A +REL K N E ++ +++ E V+ L Q +
Sbjct: 1815 KKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHER----RVKELTYQTEE-------- 1862
Query: 162 EYSNKKRLQQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEV 208
+ N RLQ L +LQ + K + E+Q+ AK K Q E+
Sbjct: 1863 DRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHEL 1909
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 51.6 bits (122), Expect = 1e-06
Identities = 54/276 (19%), Positives = 124/276 (44%), Gaps = 37/276 (13%)
Query: 93 KMHAKIWLMKTSL----RSGRAALRELRSRENFLSKLNRELIETIQEMENSTTLHVRALL 148
K ++ ++K +L RS A ++E+R + + E +E + + + + + L
Sbjct: 1171 KREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLE 1230
Query: 149 QQQDTLATIIDILEYSNKKRLQQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEV 208
++ LA + +L + K+ ++ K +L+ ++ + K S E+ +LN K+ K Q EV
Sbjct: 1231 KENADLAGELRVLGQA-KQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEV 1289
Query: 209 NFLSTYMDH---------------------------EYSIKSVQISTLMRQLQQVKDSQQ 241
++ ++ E + + + +ST +RQL++ ++S Q
Sbjct: 1290 ESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQ 1349
Query: 242 DELDDLGEMRRKV---LESLSDKIQKKKKKILSSVVAETQRPYEEALLQKMWESQDFLKC 298
D+LD+ E ++ + + +L+ ++ KKK+ A T EE + E ++ +
Sbjct: 1350 DQLDEEMEAKQNLERHISTLNIQLSDSKKKLQD--FASTVEALEEGKKRFQKEIENLTQQ 1407
Query: 299 MQRFREFIDQFEENMPVLRAEVEELQAQTREPREVI 334
+ D+ E+ L+ E+++L R+++
Sbjct: 1408 YEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLV 1443
Score = 47.0 bits (110), Expect = 3e-05
Identities = 55/271 (20%), Positives = 122/271 (45%), Gaps = 37/271 (13%)
Query: 84 HRRRKLDPGKMHAKIWLMKTSLRSGRAALRELRSRENFLSKLNRELIETIQEMENSTTLH 143
H+++KL+ A++ +++ G A EL + + L + + E E
Sbjct: 1252 HKKKKLE-----AQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKL 1306
Query: 144 VRALLQQQDTLATIIDILEYSNKKRLQQLKSELQEWEEKKKCKMSYLEQQAEQ------- 196
+ + L ++L+ +++L + ++L++ EE++ L+++ E
Sbjct: 1307 AKDVASLSSQLQDTQELLQEETRQKLN-VSTKLRQLEEERNSLQDQLDEEMEAKQNLERH 1365
Query: 197 ---LNAKIEKTQEEV-NFLSTYMDHEYSIKSVQ--ISTLMRQ----------LQQVKDSQ 240
LN ++ +++++ +F ST E K Q I L +Q L++ K+
Sbjct: 1366 ISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRL 1425
Query: 241 QDELDDLG---EMRRKVLESLSDKIQK-----KKKKILSSVVAETQRPYEEALLQKMWES 292
Q ELDDL + +R+++ +L K +K ++K +SS A+ + E +K ++
Sbjct: 1426 QQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKA 1485
Query: 293 QDFLKCMQRFREFIDQFEENMPVLRAEVEEL 323
+ ++ E ++ E +L+AE+E+L
Sbjct: 1486 LSLARALEEALEAKEELERTNKMLKAEMEDL 1516
Score = 43.5 bits (101), Expect = 3e-04
Identities = 49/233 (21%), Positives = 101/233 (43%), Gaps = 16/233 (6%)
Query: 114 ELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRLQQLK 173
EL+ + K EL E E ++S + LLQ+Q T + + RL K
Sbjct: 860 ELQKTKERQQKAENELKEL--EQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKK 917
Query: 174 SELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHE------YSIKSVQIS 227
EL+E + + ++ E + +QL A+ +K +++ L ++ E ++ V
Sbjct: 918 QELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAE 977
Query: 228 TLMRQLQQVKDSQQDELDDLGEMRRKVLESLSDKI-----QKKKKKILSSVVAETQRPYE 282
+++L+ D+ + L + R+ + E +SD +++K K L+ + + +
Sbjct: 978 AKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMIS 1037
Query: 283 E---ALLQKMWESQDFLKCMQRFREFIDQFEENMPVLRAEVEELQAQTREPRE 332
E L ++ Q+ K ++ F E + L+A++ EL+ Q + E
Sbjct: 1038 ELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEE 1090
Score = 38.9 bits (89), Expect = 0.007
Identities = 42/216 (19%), Positives = 88/216 (40%), Gaps = 15/216 (6%)
Query: 114 ELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRLQQLK 173
E R +E L R L E ++ E + + +D +++ D+ + N L++ K
Sbjct: 1477 EAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGK--NVHELEKSK 1534
Query: 174 SELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQISTLMRQL 233
L+ E+ K ++ LE + + + + + L + + + Q RQL
Sbjct: 1535 RALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQL 1594
Query: 234 QQVKDSQQDELDDLGEMRRKVLESLSDKIQKKKKKILSSVVAETQRPYEEALLQKMWESQ 293
Q+ + EL+D E +++ L + + K + K L + EEA+ Q
Sbjct: 1595 QRQLHEYETELED--ERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQ------ 1646
Query: 294 DFLKCMQRFREFIDQFEENMPVLRAEVEELQAQTRE 329
+++ + + F+ + RA +E+ A +E
Sbjct: 1647 -----LRKLQAQMKDFQRELEDARASRDEIFATAKE 1677
Score = 38.1 bits (87), Expect = 0.012
Identities = 45/257 (17%), Positives = 110/257 (42%), Gaps = 31/257 (12%)
Query: 93 KMHAKIWLMKTSLRSGRAALREL----RSRENFLSKLNRELIETIQEMENSTTLHVRALL 148
K+ A++ + L RA+ E+ + E L +L++ +++ + +A L
Sbjct: 1649 KLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADL 1708
Query: 149 QQQDTLATIIDILEYSNKKRLQQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEV 208
++++ + L N LQ+ + + + +++ LE++ E+ +E + V
Sbjct: 1709 EKEELAEELASSLSGRNA---------LQDEKRRLEARIAQLEEELEEEQGNMEAMSDRV 1759
Query: 209 NFLSTYMDHEYSIKSVQISTLMRQLQQVKDSQQDELDDLGEMRRKVLESLSDKIQKKKKK 268
+ + S +++T R Q +S + +L+ + R L + ++ K K
Sbjct: 1760 RKATQQAEQ----LSNELAT-ERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKS 1814
Query: 269 ILSSVVAETQRPYEE-------------ALLQKMWESQDFLKCMQRFREFIDQFEENMPV 315
++++ A+ + E+ +L QK + ++ L ++ R+ +Q++E
Sbjct: 1815 TIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEK 1874
Query: 316 LRAEVEELQAQTREPRE 332
A V++L+ Q E E
Sbjct: 1875 GNARVKQLKRQLEEAEE 1891
Score = 37.0 bits (84), Expect = 0.028
Identities = 45/249 (18%), Positives = 106/249 (42%), Gaps = 39/249 (15%)
Query: 113 RELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDIL---EYSNKKRL 169
+E + E +S L L E ++ +N T L + +++ + +++ E +++ L
Sbjct: 999 KERKLLEERISDLTTNLAEEEEKAKNLTKLK-----NKHESMISELEVRLKKEEKSRQEL 1053
Query: 170 QQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQISTL 229
++LK +L+ +++ L+ Q +L ++ K +EE+ +D E + K+ + +
Sbjct: 1054 EKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKI 1113
Query: 230 MRQLQQVKDSQQD-------------ELDDLGEMRRKVLESLSDKI------------QK 264
+ D Q+D + DLGE + L D + ++
Sbjct: 1114 RELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKRE 1173
Query: 265 KKKKILSSVVAETQRPYEEALLQKMWES-----QDFLKCMQRFREFIDQFEENMPVLRAE 319
++ +L + E R + EA +Q+M + ++ + +++F+ ++N L E
Sbjct: 1174 QEVTVLKKALDEETRSH-EAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKE 1232
Query: 320 VEELQAQTR 328
+L + R
Sbjct: 1233 NADLAGELR 1241
Score = 36.2 bits (82), Expect = 0.047
Identities = 37/175 (21%), Positives = 80/175 (45%), Gaps = 24/175 (13%)
Query: 101 MKTSLRSGRAALRELRSRENFLSKLNRELIETIQEMENST-----------TLHVRALLQ 149
+ L + R+ ++ S L + N+EL + EME + + L +
Sbjct: 1769 LSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEE 1828
Query: 150 QQDTLATIIDILEYSNKKRLQQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVN 209
Q + A S K++ ++LK L + E+++K Y ++QAE+ NA++++ + ++
Sbjct: 1829 QVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQY-KEQAEKGNARVKQLKRQL- 1886
Query: 210 FLSTYMDHEYSIKSVQISTLMRQLQQVKDSQQDELDDLGEMRRKVLESLSDKIQK 264
E +S +I+ R+LQ+ + DE + E + + +L K+++
Sbjct: 1887 -------EEAEEESQRINANRRKLQR----ELDEATESNEAMGREVNALKSKLRR 1930
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 51.6 bits (122), Expect = 1e-06
Identities = 54/276 (19%), Positives = 124/276 (44%), Gaps = 37/276 (13%)
Query: 93 KMHAKIWLMKTSL----RSGRAALRELRSRENFLSKLNRELIETIQEMENSTTLHVRALL 148
K ++ ++K +L RS A ++E+R + + E +E + + + + + L
Sbjct: 1178 KREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLE 1237
Query: 149 QQQDTLATIIDILEYSNKKRLQQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEV 208
++ LA + +L + K+ ++ K +L+ ++ + K S E+ +LN K+ K Q EV
Sbjct: 1238 KENADLAGELRVLGQA-KQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEV 1296
Query: 209 NFLSTYMDH---------------------------EYSIKSVQISTLMRQLQQVKDSQQ 241
++ ++ E + + + +ST +RQL++ ++S Q
Sbjct: 1297 ESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQ 1356
Query: 242 DELDDLGEMRRKV---LESLSDKIQKKKKKILSSVVAETQRPYEEALLQKMWESQDFLKC 298
D+LD+ E ++ + + +L+ ++ KKK+ A T EE + E ++ +
Sbjct: 1357 DQLDEEMEAKQNLERHISTLNIQLSDSKKKLQD--FASTVEALEEGKKRFQKEIENLTQQ 1414
Query: 299 MQRFREFIDQFEENMPVLRAEVEELQAQTREPREVI 334
+ D+ E+ L+ E+++L R+++
Sbjct: 1415 YEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLV 1450
Score = 47.0 bits (110), Expect = 3e-05
Identities = 55/271 (20%), Positives = 122/271 (45%), Gaps = 37/271 (13%)
Query: 84 HRRRKLDPGKMHAKIWLMKTSLRSGRAALRELRSRENFLSKLNRELIETIQEMENSTTLH 143
H+++KL+ A++ +++ G A EL + + L + + E E
Sbjct: 1259 HKKKKLE-----AQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKL 1313
Query: 144 VRALLQQQDTLATIIDILEYSNKKRLQQLKSELQEWEEKKKCKMSYLEQQAEQ------- 196
+ + L ++L+ +++L + ++L++ EE++ L+++ E
Sbjct: 1314 AKDVASLSSQLQDTQELLQEETRQKLN-VSTKLRQLEEERNSLQDQLDEEMEAKQNLERH 1372
Query: 197 ---LNAKIEKTQEEV-NFLSTYMDHEYSIKSVQ--ISTLMRQ----------LQQVKDSQ 240
LN ++ +++++ +F ST E K Q I L +Q L++ K+
Sbjct: 1373 ISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRL 1432
Query: 241 QDELDDLG---EMRRKVLESLSDKIQK-----KKKKILSSVVAETQRPYEEALLQKMWES 292
Q ELDDL + +R+++ +L K +K ++K +SS A+ + E +K ++
Sbjct: 1433 QQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKA 1492
Query: 293 QDFLKCMQRFREFIDQFEENMPVLRAEVEEL 323
+ ++ E ++ E +L+AE+E+L
Sbjct: 1493 LSLARALEEALEAKEELERTNKMLKAEMEDL 1523
Score = 43.5 bits (101), Expect = 3e-04
Identities = 49/233 (21%), Positives = 101/233 (43%), Gaps = 16/233 (6%)
Query: 114 ELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRLQQLK 173
EL+ + K EL E E ++S + LLQ+Q T + + RL K
Sbjct: 867 ELQKTKERQQKAENELKEL--EQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKK 924
Query: 174 SELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHE------YSIKSVQIS 227
EL+E + + ++ E + +QL A+ +K +++ L ++ E ++ V
Sbjct: 925 QELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAE 984
Query: 228 TLMRQLQQVKDSQQDELDDLGEMRRKVLESLSDKI-----QKKKKKILSSVVAETQRPYE 282
+++L+ D+ + L + R+ + E +SD +++K K L+ + + +
Sbjct: 985 AKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMIS 1044
Query: 283 E---ALLQKMWESQDFLKCMQRFREFIDQFEENMPVLRAEVEELQAQTREPRE 332
E L ++ Q+ K ++ F E + L+A++ EL+ Q + E
Sbjct: 1045 ELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEE 1097
Score = 38.9 bits (89), Expect = 0.007
Identities = 42/216 (19%), Positives = 88/216 (40%), Gaps = 15/216 (6%)
Query: 114 ELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRLQQLK 173
E R +E L R L E ++ E + + +D +++ D+ + N L++ K
Sbjct: 1484 EAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGK--NVHELEKSK 1541
Query: 174 SELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQISTLMRQL 233
L+ E+ K ++ LE + + + + + L + + + Q RQL
Sbjct: 1542 RALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQL 1601
Query: 234 QQVKDSQQDELDDLGEMRRKVLESLSDKIQKKKKKILSSVVAETQRPYEEALLQKMWESQ 293
Q+ + EL+D E +++ L + + K + K L + EEA+ Q
Sbjct: 1602 QRQLHEYETELED--ERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQ------ 1653
Query: 294 DFLKCMQRFREFIDQFEENMPVLRAEVEELQAQTRE 329
+++ + + F+ + RA +E+ A +E
Sbjct: 1654 -----LRKLQAQMKDFQRELEDARASRDEIFATAKE 1684
Score = 38.1 bits (87), Expect = 0.012
Identities = 45/257 (17%), Positives = 110/257 (42%), Gaps = 31/257 (12%)
Query: 93 KMHAKIWLMKTSLRSGRAALREL----RSRENFLSKLNRELIETIQEMENSTTLHVRALL 148
K+ A++ + L RA+ E+ + E L +L++ +++ + +A L
Sbjct: 1656 KLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADL 1715
Query: 149 QQQDTLATIIDILEYSNKKRLQQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEV 208
++++ + L N LQ+ + + + +++ LE++ E+ +E + V
Sbjct: 1716 EKEELAEELASSLSGRNA---------LQDEKRRLEARIAQLEEELEEEQGNMEAMSDRV 1766
Query: 209 NFLSTYMDHEYSIKSVQISTLMRQLQQVKDSQQDELDDLGEMRRKVLESLSDKIQKKKKK 268
+ + S +++T R Q +S + +L+ + R L + ++ K K
Sbjct: 1767 RKATQQAEQ----LSNELAT-ERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKS 1821
Query: 269 ILSSVVAETQRPYEE-------------ALLQKMWESQDFLKCMQRFREFIDQFEENMPV 315
++++ A+ + E+ +L QK + ++ L ++ R+ +Q++E
Sbjct: 1822 TIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEK 1881
Query: 316 LRAEVEELQAQTREPRE 332
A V++L+ Q E E
Sbjct: 1882 GNARVKQLKRQLEEAEE 1898
Score = 37.0 bits (84), Expect = 0.028
Identities = 45/249 (18%), Positives = 106/249 (42%), Gaps = 39/249 (15%)
Query: 113 RELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDIL---EYSNKKRL 169
+E + E +S L L E ++ +N T L + +++ + +++ E +++ L
Sbjct: 1006 KERKLLEERISDLTTNLAEEEEKAKNLTKLK-----NKHESMISELEVRLKKEEKSRQEL 1060
Query: 170 QQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQISTL 229
++LK +L+ +++ L+ Q +L ++ K +EE+ +D E + K+ + +
Sbjct: 1061 EKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKI 1120
Query: 230 MRQLQQVKDSQQD-------------ELDDLGEMRRKVLESLSDKI------------QK 264
+ D Q+D + DLGE + L D + ++
Sbjct: 1121 RELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKRE 1180
Query: 265 KKKKILSSVVAETQRPYEEALLQKMWES-----QDFLKCMQRFREFIDQFEENMPVLRAE 319
++ +L + E R + EA +Q+M + ++ + +++F+ ++N L E
Sbjct: 1181 QEVTVLKKALDEETRSH-EAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKE 1239
Query: 320 VEELQAQTR 328
+L + R
Sbjct: 1240 NADLAGELR 1248
Score = 36.2 bits (82), Expect = 0.047
Identities = 37/175 (21%), Positives = 80/175 (45%), Gaps = 24/175 (13%)
Query: 101 MKTSLRSGRAALRELRSRENFLSKLNRELIETIQEMENST-----------TLHVRALLQ 149
+ L + R+ ++ S L + N+EL + EME + + L +
Sbjct: 1776 LSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEE 1835
Query: 150 QQDTLATIIDILEYSNKKRLQQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVN 209
Q + A S K++ ++LK L + E+++K Y ++QAE+ NA++++ + ++
Sbjct: 1836 QVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQY-KEQAEKGNARVKQLKRQL- 1893
Query: 210 FLSTYMDHEYSIKSVQISTLMRQLQQVKDSQQDELDDLGEMRRKVLESLSDKIQK 264
E +S +I+ R+LQ+ + DE + E + + +L K+++
Sbjct: 1894 -------EEAEEESQRINANRRKLQR----ELDEATESNEAMGREVNALKSKLRR 1937
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 51.6 bits (122), Expect = 1e-06
Identities = 54/276 (19%), Positives = 124/276 (44%), Gaps = 37/276 (13%)
Query: 93 KMHAKIWLMKTSL----RSGRAALRELRSRENFLSKLNRELIETIQEMENSTTLHVRALL 148
K ++ ++K +L RS A ++E+R + + E +E + + + + + L
Sbjct: 1178 KREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLE 1237
Query: 149 QQQDTLATIIDILEYSNKKRLQQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEV 208
++ LA + +L + K+ ++ K +L+ ++ + K S E+ +LN K+ K Q EV
Sbjct: 1238 KENADLAGELRVLGQA-KQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEV 1296
Query: 209 NFLSTYMDH---------------------------EYSIKSVQISTLMRQLQQVKDSQQ 241
++ ++ E + + + +ST +RQL++ ++S Q
Sbjct: 1297 ESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQ 1356
Query: 242 DELDDLGEMRRKV---LESLSDKIQKKKKKILSSVVAETQRPYEEALLQKMWESQDFLKC 298
D+LD+ E ++ + + +L+ ++ KKK+ A T EE + E ++ +
Sbjct: 1357 DQLDEEMEAKQNLERHISTLNIQLSDSKKKLQD--FASTVEALEEGKKRFQKEIENLTQQ 1414
Query: 299 MQRFREFIDQFEENMPVLRAEVEELQAQTREPREVI 334
+ D+ E+ L+ E+++L R+++
Sbjct: 1415 YEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLV 1450
Score = 47.0 bits (110), Expect = 3e-05
Identities = 55/271 (20%), Positives = 122/271 (45%), Gaps = 37/271 (13%)
Query: 84 HRRRKLDPGKMHAKIWLMKTSLRSGRAALRELRSRENFLSKLNRELIETIQEMENSTTLH 143
H+++KL+ A++ +++ G A EL + + L + + E E
Sbjct: 1259 HKKKKLE-----AQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKL 1313
Query: 144 VRALLQQQDTLATIIDILEYSNKKRLQQLKSELQEWEEKKKCKMSYLEQQAEQ------- 196
+ + L ++L+ +++L + ++L++ EE++ L+++ E
Sbjct: 1314 AKDVASLSSQLQDTQELLQEETRQKLN-VSTKLRQLEEERNSLQDQLDEEMEAKQNLERH 1372
Query: 197 ---LNAKIEKTQEEV-NFLSTYMDHEYSIKSVQ--ISTLMRQ----------LQQVKDSQ 240
LN ++ +++++ +F ST E K Q I L +Q L++ K+
Sbjct: 1373 ISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRL 1432
Query: 241 QDELDDLG---EMRRKVLESLSDKIQK-----KKKKILSSVVAETQRPYEEALLQKMWES 292
Q ELDDL + +R+++ +L K +K ++K +SS A+ + E +K ++
Sbjct: 1433 QQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKA 1492
Query: 293 QDFLKCMQRFREFIDQFEENMPVLRAEVEEL 323
+ ++ E ++ E +L+AE+E+L
Sbjct: 1493 LSLARALEEALEAKEELERTNKMLKAEMEDL 1523
Score = 43.5 bits (101), Expect = 3e-04
Identities = 49/233 (21%), Positives = 101/233 (43%), Gaps = 16/233 (6%)
Query: 114 ELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRLQQLK 173
EL+ + K EL E E ++S + LLQ+Q T + + RL K
Sbjct: 867 ELQKTKERQQKAENELKEL--EQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKK 924
Query: 174 SELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHE------YSIKSVQIS 227
EL+E + + ++ E + +QL A+ +K +++ L ++ E ++ V
Sbjct: 925 QELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAE 984
Query: 228 TLMRQLQQVKDSQQDELDDLGEMRRKVLESLSDKI-----QKKKKKILSSVVAETQRPYE 282
+++L+ D+ + L + R+ + E +SD +++K K L+ + + +
Sbjct: 985 AKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMIS 1044
Query: 283 E---ALLQKMWESQDFLKCMQRFREFIDQFEENMPVLRAEVEELQAQTREPRE 332
E L ++ Q+ K ++ F E + L+A++ EL+ Q + E
Sbjct: 1045 ELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEE 1097
Score = 38.9 bits (89), Expect = 0.007
Identities = 42/216 (19%), Positives = 88/216 (40%), Gaps = 15/216 (6%)
Query: 114 ELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRLQQLK 173
E R +E L R L E ++ E + + +D +++ D+ + N L++ K
Sbjct: 1484 EAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGK--NVHELEKSK 1541
Query: 174 SELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQISTLMRQL 233
L+ E+ K ++ LE + + + + + L + + + Q RQL
Sbjct: 1542 RALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQL 1601
Query: 234 QQVKDSQQDELDDLGEMRRKVLESLSDKIQKKKKKILSSVVAETQRPYEEALLQKMWESQ 293
Q+ + EL+D E +++ L + + K + K L + EEA+ Q
Sbjct: 1602 QRQLHEYETELED--ERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQ------ 1653
Query: 294 DFLKCMQRFREFIDQFEENMPVLRAEVEELQAQTRE 329
+++ + + F+ + RA +E+ A +E
Sbjct: 1654 -----LRKLQAQMKDFQRELEDARASRDEIFATAKE 1684
Score = 38.1 bits (87), Expect = 0.012
Identities = 45/257 (17%), Positives = 110/257 (42%), Gaps = 31/257 (12%)
Query: 93 KMHAKIWLMKTSLRSGRAALREL----RSRENFLSKLNRELIETIQEMENSTTLHVRALL 148
K+ A++ + L RA+ E+ + E L +L++ +++ + +A L
Sbjct: 1656 KLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADL 1715
Query: 149 QQQDTLATIIDILEYSNKKRLQQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEV 208
++++ + L N LQ+ + + + +++ LE++ E+ +E + V
Sbjct: 1716 EKEELAEELASSLSGRNA---------LQDEKRRLEARIAQLEEELEEEQGNMEAMSDRV 1766
Query: 209 NFLSTYMDHEYSIKSVQISTLMRQLQQVKDSQQDELDDLGEMRRKVLESLSDKIQKKKKK 268
+ + S +++T R Q +S + +L+ + R L + ++ K K
Sbjct: 1767 RKATQQAEQ----LSNELAT-ERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKS 1821
Query: 269 ILSSVVAETQRPYEE-------------ALLQKMWESQDFLKCMQRFREFIDQFEENMPV 315
++++ A+ + E+ +L QK + ++ L ++ R+ +Q++E
Sbjct: 1822 TIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEK 1881
Query: 316 LRAEVEELQAQTREPRE 332
A V++L+ Q E E
Sbjct: 1882 GNARVKQLKRQLEEAEE 1898
Score = 37.0 bits (84), Expect = 0.028
Identities = 45/249 (18%), Positives = 106/249 (42%), Gaps = 39/249 (15%)
Query: 113 RELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDIL---EYSNKKRL 169
+E + E +S L L E ++ +N T L + +++ + +++ E +++ L
Sbjct: 1006 KERKLLEERISDLTTNLAEEEEKAKNLTKLK-----NKHESMISELEVRLKKEEKSRQEL 1060
Query: 170 QQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQISTL 229
++LK +L+ +++ L+ Q +L ++ K +EE+ +D E + K+ + +
Sbjct: 1061 EKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKI 1120
Query: 230 MRQLQQVKDSQQD-------------ELDDLGEMRRKVLESLSDKI------------QK 264
+ D Q+D + DLGE + L D + ++
Sbjct: 1121 RELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKRE 1180
Query: 265 KKKKILSSVVAETQRPYEEALLQKMWES-----QDFLKCMQRFREFIDQFEENMPVLRAE 319
++ +L + E R + EA +Q+M + ++ + +++F+ ++N L E
Sbjct: 1181 QEVTVLKKALDEETRSH-EAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKE 1239
Query: 320 VEELQAQTR 328
+L + R
Sbjct: 1240 NADLAGELR 1248
Score = 35.4 bits (80), Expect = 0.080
Identities = 37/174 (21%), Positives = 79/174 (45%), Gaps = 24/174 (13%)
Query: 101 MKTSLRSGRAALRELRSRENFLSKLNRELIETIQEMENST-----------TLHVRALLQ 149
+ L + R+ ++ S L + N+EL + EME + + L +
Sbjct: 1776 LSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEE 1835
Query: 150 QQDTLATIIDILEYSNKKRLQQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVN 209
Q + A S K++ ++LK L + E+++K Y ++QAE+ NA++++ + ++
Sbjct: 1836 QVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQY-KEQAEKGNARVKQLKRQL- 1893
Query: 210 FLSTYMDHEYSIKSVQISTLMRQLQQVKDSQQDELDDLGEMRRKVLESLSDKIQ 263
E +S +I+ R+LQ+ + DE + E + + +L K++
Sbjct: 1894 -------EEAEEESQRINANRRKLQR----ELDEATESNEAMGREVNALKSKLR 1936
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 51.6 bits (122), Expect = 1e-06
Identities = 54/276 (19%), Positives = 124/276 (44%), Gaps = 37/276 (13%)
Query: 93 KMHAKIWLMKTSL----RSGRAALRELRSRENFLSKLNRELIETIQEMENSTTLHVRALL 148
K ++ ++K +L RS A ++E+R + + E +E + + + + + L
Sbjct: 1171 KREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLE 1230
Query: 149 QQQDTLATIIDILEYSNKKRLQQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEV 208
++ LA + +L + K+ ++ K +L+ ++ + K S E+ +LN K+ K Q EV
Sbjct: 1231 KENADLAGELRVLGQA-KQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEV 1289
Query: 209 NFLSTYMDH---------------------------EYSIKSVQISTLMRQLQQVKDSQQ 241
++ ++ E + + + +ST +RQL++ ++S Q
Sbjct: 1290 ESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQ 1349
Query: 242 DELDDLGEMRRKV---LESLSDKIQKKKKKILSSVVAETQRPYEEALLQKMWESQDFLKC 298
D+LD+ E ++ + + +L+ ++ KKK+ A T EE + E ++ +
Sbjct: 1350 DQLDEEMEAKQNLERHISTLNIQLSDSKKKLQD--FASTVEALEEGKKRFQKEIENLTQQ 1407
Query: 299 MQRFREFIDQFEENMPVLRAEVEELQAQTREPREVI 334
+ D+ E+ L+ E+++L R+++
Sbjct: 1408 YEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLV 1443
Score = 47.0 bits (110), Expect = 3e-05
Identities = 55/271 (20%), Positives = 122/271 (45%), Gaps = 37/271 (13%)
Query: 84 HRRRKLDPGKMHAKIWLMKTSLRSGRAALRELRSRENFLSKLNRELIETIQEMENSTTLH 143
H+++KL+ A++ +++ G A EL + + L + + E E
Sbjct: 1252 HKKKKLE-----AQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKL 1306
Query: 144 VRALLQQQDTLATIIDILEYSNKKRLQQLKSELQEWEEKKKCKMSYLEQQAEQ------- 196
+ + L ++L+ +++L + ++L++ EE++ L+++ E
Sbjct: 1307 AKDVASLSSQLQDTQELLQEETRQKLN-VSTKLRQLEEERNSLQDQLDEEMEAKQNLERH 1365
Query: 197 ---LNAKIEKTQEEV-NFLSTYMDHEYSIKSVQ--ISTLMRQ----------LQQVKDSQ 240
LN ++ +++++ +F ST E K Q I L +Q L++ K+
Sbjct: 1366 ISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRL 1425
Query: 241 QDELDDLG---EMRRKVLESLSDKIQK-----KKKKILSSVVAETQRPYEEALLQKMWES 292
Q ELDDL + +R+++ +L K +K ++K +SS A+ + E +K ++
Sbjct: 1426 QQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKA 1485
Query: 293 QDFLKCMQRFREFIDQFEENMPVLRAEVEEL 323
+ ++ E ++ E +L+AE+E+L
Sbjct: 1486 LSLARALEEALEAKEELERTNKMLKAEMEDL 1516
Score = 43.5 bits (101), Expect = 3e-04
Identities = 49/233 (21%), Positives = 101/233 (43%), Gaps = 16/233 (6%)
Query: 114 ELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRLQQLK 173
EL+ + K EL E E ++S + LLQ+Q T + + RL K
Sbjct: 860 ELQKTKERQQKAENELKEL--EQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKK 917
Query: 174 SELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHE------YSIKSVQIS 227
EL+E + + ++ E + +QL A+ +K +++ L ++ E ++ V
Sbjct: 918 QELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAE 977
Query: 228 TLMRQLQQVKDSQQDELDDLGEMRRKVLESLSDKI-----QKKKKKILSSVVAETQRPYE 282
+++L+ D+ + L + R+ + E +SD +++K K L+ + + +
Sbjct: 978 AKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMIS 1037
Query: 283 E---ALLQKMWESQDFLKCMQRFREFIDQFEENMPVLRAEVEELQAQTREPRE 332
E L ++ Q+ K ++ F E + L+A++ EL+ Q + E
Sbjct: 1038 ELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEE 1090
Score = 38.9 bits (89), Expect = 0.007
Identities = 42/216 (19%), Positives = 88/216 (40%), Gaps = 15/216 (6%)
Query: 114 ELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRLQQLK 173
E R +E L R L E ++ E + + +D +++ D+ + N L++ K
Sbjct: 1477 EAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGK--NVHELEKSK 1534
Query: 174 SELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQISTLMRQL 233
L+ E+ K ++ LE + + + + + L + + + Q RQL
Sbjct: 1535 RALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQL 1594
Query: 234 QQVKDSQQDELDDLGEMRRKVLESLSDKIQKKKKKILSSVVAETQRPYEEALLQKMWESQ 293
Q+ + EL+D E +++ L + + K + K L + EEA+ Q
Sbjct: 1595 QRQLHEYETELED--ERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQ------ 1646
Query: 294 DFLKCMQRFREFIDQFEENMPVLRAEVEELQAQTRE 329
+++ + + F+ + RA +E+ A +E
Sbjct: 1647 -----LRKLQAQMKDFQRELEDARASRDEIFATAKE 1677
Score = 38.1 bits (87), Expect = 0.012
Identities = 45/257 (17%), Positives = 110/257 (42%), Gaps = 31/257 (12%)
Query: 93 KMHAKIWLMKTSLRSGRAALREL----RSRENFLSKLNRELIETIQEMENSTTLHVRALL 148
K+ A++ + L RA+ E+ + E L +L++ +++ + +A L
Sbjct: 1649 KLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADL 1708
Query: 149 QQQDTLATIIDILEYSNKKRLQQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEV 208
++++ + L N LQ+ + + + +++ LE++ E+ +E + V
Sbjct: 1709 EKEELAEELASSLSGRNA---------LQDEKRRLEARIAQLEEELEEEQGNMEAMSDRV 1759
Query: 209 NFLSTYMDHEYSIKSVQISTLMRQLQQVKDSQQDELDDLGEMRRKVLESLSDKIQKKKKK 268
+ + S +++T R Q +S + +L+ + R L + ++ K K
Sbjct: 1760 RKATQQAEQ----LSNELAT-ERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKS 1814
Query: 269 ILSSVVAETQRPYEE-------------ALLQKMWESQDFLKCMQRFREFIDQFEENMPV 315
++++ A+ + E+ +L QK + ++ L ++ R+ +Q++E
Sbjct: 1815 TIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEK 1874
Query: 316 LRAEVEELQAQTREPRE 332
A V++L+ Q E E
Sbjct: 1875 GNARVKQLKRQLEEAEE 1891
Score = 37.0 bits (84), Expect = 0.028
Identities = 45/249 (18%), Positives = 106/249 (42%), Gaps = 39/249 (15%)
Query: 113 RELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDIL---EYSNKKRL 169
+E + E +S L L E ++ +N T L + +++ + +++ E +++ L
Sbjct: 999 KERKLLEERISDLTTNLAEEEEKAKNLTKLK-----NKHESMISELEVRLKKEEKSRQEL 1053
Query: 170 QQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQISTL 229
++LK +L+ +++ L+ Q +L ++ K +EE+ +D E + K+ + +
Sbjct: 1054 EKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKI 1113
Query: 230 MRQLQQVKDSQQD-------------ELDDLGEMRRKVLESLSDKI------------QK 264
+ D Q+D + DLGE + L D + ++
Sbjct: 1114 RELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKRE 1173
Query: 265 KKKKILSSVVAETQRPYEEALLQKMWES-----QDFLKCMQRFREFIDQFEENMPVLRAE 319
++ +L + E R + EA +Q+M + ++ + +++F+ ++N L E
Sbjct: 1174 QEVTVLKKALDEETRSH-EAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKE 1232
Query: 320 VEELQAQTR 328
+L + R
Sbjct: 1233 NADLAGELR 1241
Score = 35.4 bits (80), Expect = 0.080
Identities = 37/174 (21%), Positives = 79/174 (45%), Gaps = 24/174 (13%)
Query: 101 MKTSLRSGRAALRELRSRENFLSKLNRELIETIQEMENST-----------TLHVRALLQ 149
+ L + R+ ++ S L + N+EL + EME + + L +
Sbjct: 1769 LSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEE 1828
Query: 150 QQDTLATIIDILEYSNKKRLQQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVN 209
Q + A S K++ ++LK L + E+++K Y ++QAE+ NA++++ + ++
Sbjct: 1829 QVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQY-KEQAEKGNARVKQLKRQL- 1886
Query: 210 FLSTYMDHEYSIKSVQISTLMRQLQQVKDSQQDELDDLGEMRRKVLESLSDKIQ 263
E +S +I+ R+LQ+ + DE + E + + +L K++
Sbjct: 1887 -------EEAEEESQRINANRRKLQR----ELDEATESNEAMGREVNALKSKLR 1929
>gi|8922940 gamma-taxilin [Homo sapiens]
Length = 528
Score = 51.2 bits (121), Expect = 1e-06
Identities = 46/240 (19%), Positives = 113/240 (47%), Gaps = 16/240 (6%)
Query: 112 LRELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRLQQ 171
L E RS + + L ++ + ++E + + H +A+L + L ++ L+ NK ++
Sbjct: 167 LEESRSVQKQMKILQKKQAQIVKEKVHLQSEHSKAILARSK-LESLCRELQRHNKTLKEE 225
Query: 172 LKSELQEWEEKKK-------CKMSYLEQQAEQL---NAKIEKTQEEVNFLSTYMDHEYSI 221
+ +E EE++K + ++ Q EQ NAK+ + E+ + +Y++
Sbjct: 226 NMQQAREEEERRKEATAHFQITLDEIQAQLEQHDIHNAKLRQENIELGEKLKKLIEQYAL 285
Query: 222 KSVQISTLMRQLQQVKDSQQDELDDLGEMRRKVLESLSDKIQKKKKKILSSVVAETQRPY 281
+ I + ++ K+ QQ +D + ++++ +K Q++++ +L E++ Y
Sbjct: 286 REEHIDKVFKR----KELQQQLVDAKLQQTTQLIKEADEKHQREREFLLKEAT-ESRHKY 340
Query: 282 EEALLQKMWESQDFLKCMQRFREFIDQFEENMPVLRAEVEELQAQTREPREVIFEDVLLR 341
E+ Q++ Q M +F EF ++ + +E++ T++ +++ E ++ R
Sbjct: 341 EQMKQQEVQLKQQLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIKKLEKETIIWR 400
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 50.4 bits (119), Expect = 2e-06
Identities = 62/271 (22%), Positives = 130/271 (47%), Gaps = 33/271 (12%)
Query: 84 HRRRKLDPG--KMHAKIW---LMKTSLRSGRAALR-ELRSRENFLSKLNRELIETIQEME 137
H+R+KLD ++HAK+ ++ L + L+ EL + L + ++ I+ ++
Sbjct: 1252 HKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAA 1311
Query: 138 N--STTLHVRALLQQQDTLATIIDILEYSNKKRLQQLKSELQEWEEKKKCKMSYLEQQAE 195
+ S + LLQ++ + S ++L++ K+ LQE +E+++ LE+Q
Sbjct: 1312 SLESQLQDTQELLQEETRQKLNLS----SRIRQLEEEKNSLQEQQEEEEEARKNLEKQVL 1367
Query: 196 QLNAKIEKTQEEV-NFLSTYMDHEYSIKSV------------QISTLMRQLQQVKDSQQD 242
L +++ T+++V + L T E + K + + + +L++ K+ Q
Sbjct: 1368 ALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQ 1427
Query: 243 ELDDLG---EMRRKVLESLSDKIQK-----KKKKILSSVVAETQRPYEEALLQKMWESQD 294
ELDDL + +R+V +L K +K ++K +S+ AE + E +K ++
Sbjct: 1428 ELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALS 1487
Query: 295 FLKCMQRFREFIDQFEENMPVLRAEVEELQA 325
+ ++ E ++FE LRA++E+L +
Sbjct: 1488 LARALEEALEAKEEFERQNKQLRADMEDLMS 1518
Score = 45.1 bits (105), Expect = 1e-04
Identities = 60/264 (22%), Positives = 111/264 (42%), Gaps = 45/264 (17%)
Query: 93 KMHAKIWLMKTSLRSGRAALREL----RSRENFLSKLNRELIETIQEMENSTTLHVRALL 148
K+ A++ + L RA+ E+ + E L L E+++ +E+ +S R
Sbjct: 1649 KLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERAR-RHAE 1707
Query: 149 QQQDTLATIIDILE------YSNKKRLQQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIE 202
Q++D LA I K+RL+ ++L+E E+++ M E LN +
Sbjct: 1708 QERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNM-------ELLNDRFR 1760
Query: 203 KTQEEVNFLSTYMDHEYSIKSVQISTLMRQLQQVKDSQQDELDDLGEMRRKVLESLSDKI 262
KT +V+ L+ + E R Q D+ + +L+ + + L+ L +
Sbjct: 1761 KTTLQVDTLNAELAAE------------RSAAQKSDNARQQLERQNKELKAKLQELEGAV 1808
Query: 263 QKKKKKILSSVVAETQRPYEEALLQKMWESQDFLKCMQRF--------------REFIDQ 308
+ K K +S++ A+ + EE L Q+ E K ++R R DQ
Sbjct: 1809 KSKFKATISALEAKIGQ-LEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQ 1867
Query: 309 FEENMPVLRAEVEELQAQTREPRE 332
++E M A +++L+ Q E E
Sbjct: 1868 YKEQMEKANARMKQLKRQLEEAEE 1891
Score = 41.6 bits (96), Expect = 0.001
Identities = 53/242 (21%), Positives = 105/242 (43%), Gaps = 39/242 (16%)
Query: 110 AALRELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRL 169
A E+R+R L+ +EL E + ++E+ +++++ I+ + KK++
Sbjct: 904 AEAEEMRAR---LAAKKQELEEILHDLESR--------VEEEEERNQILQ----NEKKKM 948
Query: 170 QQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDH------------ 217
Q +L+E ++++ L+ + AKI+K +EE+ L
Sbjct: 949 QAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRI 1008
Query: 218 -EYSIKSVQISTLMRQLQQVKDSQQDELDDLGEMRRKVLESLSDKIQKKKKKI------L 270
E S + + + L ++++ Q+ + DL E R K E +++K K+K+ L
Sbjct: 1009 AECSSQLAEEEEKAKNLAKIRNKQEVMISDL-EERLKKEEKTRQELEKAKRKLDGETTDL 1067
Query: 271 SSVVAETQRPYEEALLQKMWESQDFLKCMQRFREFIDQFEENMPVLRAEVEELQAQTREP 330
+AE Q +E LQ + ++ + R + + V+R ELQAQ E
Sbjct: 1068 QDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVR----ELQAQIAEL 1123
Query: 331 RE 332
+E
Sbjct: 1124 QE 1125
Score = 40.0 bits (92), Expect = 0.003
Identities = 63/304 (20%), Positives = 126/304 (41%), Gaps = 82/304 (26%)
Query: 110 AALRELRS-RENFLSKLNRELIET-------IQEMENSTTLHVRALLQQQDTLATIIDIL 161
AA +ELR+ RE +++L + L E IQ+M + L +Q + L
Sbjct: 1163 AAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANL 1222
Query: 162 EYSNKKRLQQLKSEL-------QEWEEKKKCKMSYLEQQAEQLNAKI------------- 201
E NK+ L+ EL Q+ + + + K L+ Q ++L+AK+
Sbjct: 1223 E-KNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEK 1281
Query: 202 -EKTQEEVNFLSTYMD---------------------------HEYSIKSVQISTLMRQL 233
K Q E++ +ST ++ E + + + +S+ +RQL
Sbjct: 1282 ASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQL 1341
Query: 234 QQVKDSQQDELDD------------------LGEMRRKVLESLS--DKIQKKKKKILSSV 273
++ K+S Q++ ++ L + ++KV + L + +++ KKK+L
Sbjct: 1342 EEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDA 1401
Query: 274 VAETQRPYEEALLQKMWESQDFLKCMQRFREFIDQFEENMPVLRAEVEELQAQTREPREV 333
A +QR E+AL E K R ++ +D ++ R L+ + ++ ++
Sbjct: 1402 EALSQRLEEKALAYDKLE-----KTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQL 1456
Query: 334 IFED 337
+ E+
Sbjct: 1457 LAEE 1460
Score = 35.0 bits (79), Expect = 0.10
Identities = 39/187 (20%), Positives = 82/187 (43%), Gaps = 14/187 (7%)
Query: 166 KKRLQQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQ 225
K++ +++ EL+E E K + + AEQL A+ E E + M + K +
Sbjct: 865 KEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAE-----AEEMRARLAAKKQE 919
Query: 226 ISTLMRQLQQVKDSQQDELDDLGEMRRKVL-------ESLSDKIQKKKKKILSSVVAETQ 278
+ ++ L+ + +++ L ++K+ E L ++ ++K L V AE +
Sbjct: 920 LEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAK 979
Query: 279 -RPYEEALLQKMWESQDFLKCMQRFREFIDQFEENMPVLRAEVEELQAQTREPREVIFED 337
+ EE +L ++ F+K + + I + + + + L A+ R +EV+ D
Sbjct: 980 IKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNL-AKIRNKQEVMISD 1038
Query: 338 VLLRRPK 344
+ R K
Sbjct: 1039 LEERLKK 1045
Score = 33.5 bits (75), Expect = 0.31
Identities = 31/160 (19%), Positives = 73/160 (45%), Gaps = 19/160 (11%)
Query: 101 MKTSLRSGRAALRELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDI 160
+ L + R+A ++ + L + N+EL +QE+E + +A + +
Sbjct: 1769 LNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEA------- 1821
Query: 161 LEYSNKKRLQQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYS 220
++ QL+ +L++ E K++ + L ++ E+ K+++ +V + D +Y
Sbjct: 1822 -------KIGQLEEQLEQ-EAKERAAANKLVRRTEK---KLKEIFMQVEDERRHAD-QYK 1869
Query: 221 IKSVQISTLMRQLQQVKDSQQDELDDLGEMRRKVLESLSD 260
+ + + M+QL++ + ++E RRK+ L D
Sbjct: 1870 EQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDD 1909
Score = 32.7 bits (73), Expect = 0.52
Identities = 37/193 (19%), Positives = 90/193 (46%), Gaps = 15/193 (7%)
Query: 112 LRELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKR--L 169
++E + E+ +++ + +L E ++ +N + + Q+ ++ + + L+ K R L
Sbjct: 998 IKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNK----QEVMISDLEERLKKEEKTRQEL 1053
Query: 170 QQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQISTL 229
++ K +L + +++ L+ Q ++L ++ K +EE+ D E K+ + +
Sbjct: 1054 EKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVV 1113
Query: 230 MRQLQQVKDSQQDELDDLGEMRR--KVLESLSDKIQKKKKKI---LSSVVAE----TQRP 280
Q+ + Q+D + + K LS++++ K ++ L + A+ T+R
Sbjct: 1114 RELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKRE 1173
Query: 281 YEEALLQKMWESQ 293
E A L+K E +
Sbjct: 1174 QEVAELKKALEEE 1186
>gi|34878904 synaptonemal complex protein 1 [Homo sapiens]
Length = 976
Score = 49.7 bits (117), Expect = 4e-06
Identities = 54/261 (20%), Positives = 115/261 (44%), Gaps = 39/261 (14%)
Query: 101 MKTSLRSGRAALRELRSRENFLSKLNRELIETIQEME----------NSTTLHVRALLQQ 150
+KT L + + EL S N LS N+EL + +M N+ +L+Q
Sbjct: 502 LKTELENEKLKNTELTSHCNKLSLENKELTQETSDMTLELKNQQEDINNNKKQEERMLKQ 561
Query: 151 QDTLATIIDILEYSNKKRLQQLKSELQEWEEKKKCKM-------SYLEQQAEQLNAKIEK 203
+ L E + L+ ++ EL++ ++ KCK+ + L +Q E N IE+
Sbjct: 562 IENLQE----TETQLRNELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEE 617
Query: 204 TQEEVNFL---STYMDHEYSIKSVQISTLMRQLQQVK-------DSQQDELDDLGEMRRK 253
Q+E L T + ++ ++++ L +L+ K D+ Q E++D
Sbjct: 618 LQQENKALKKKGTAESKQLNVYEIKVNKLELELESAKQKFGEITDTYQKEIEDKKISEEN 677
Query: 254 VLESLSDKIQKKKKKILSSVVAETQRPYEEALLQKMWESQDFL-KCMQRFREFIDQFEEN 312
+LE + +K K+++ + Q+ ++ K+ E + K ++ + I++ +
Sbjct: 678 LLEEV------EKAKVIADEAVKLQKEIDKRCQHKIAEMVALMEKHKHQYDKIIEERDSE 731
Query: 313 MPVLRAEVEELQAQTREPREV 333
+ + +++ +E Q+ R E+
Sbjct: 732 LGLYKSKEQE-QSSLRASLEI 751
Score = 33.5 bits (75), Expect = 0.31
Identities = 65/355 (18%), Positives = 145/355 (40%), Gaps = 54/355 (15%)
Query: 24 DYVPWQQSKQETKPSTLPPVQQANSL------HTSKMKTLTRVQPVFHFKPTTVV--TSC 75
DY Q +QE K +Q + L +KMK LT + K + T
Sbjct: 246 DYEKIQHLEQEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKVNQLEEKTKL 305
Query: 76 QPKNPRE-LHRRRKLDPGKMHAKIWLMKTSLRSGRAALRELRSRENFLSKLNRELIETIQ 134
Q +N ++ + ++ L K+ L + S+ + +A +L+ + +L E ++
Sbjct: 306 QSENLKQSIEKQHHLTKELEDIKVSLQR-SVSTQKALEEDLQIATKTICQLTEEKETQME 364
Query: 135 EMENSTTLHVRALLQQQDTLATIIDILEYSNKKRLQQLKSELQ----------------- 177
E + H + + + T+ ++ ++L + ++RL++ + +L+
Sbjct: 365 ESNKARAAHSFVVTEFETTVCSLEELLR-TEQQRLEKNEDQLKILTMELQKKSSELEEMT 423
Query: 178 --------EWEEKKKC-----KMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSV 224
E EE KK + Y +Q E++ +++ T++E+ L + E +
Sbjct: 424 KLTNNKEVELEELKKVLGEKETLLYENKQFEKIAEELKGTEQELIGLLQAREKEVHDLEI 483
Query: 225 QISTLMRQLQQVKDSQQDELDDL--GEMRRKVLESLSDKIQKKKKKI---LSSVVAETQR 279
Q++ + Q +D +L +++ L S +K+ + K++ S + E +
Sbjct: 484 QLTAITTSEQYYSKEVKDLKTELENEKLKNTELTSHCNKLSLENKELTQETSDMTLELKN 543
Query: 280 PYEEALLQKMWESQDFLKCMQRFREFIDQFEENMPVLRAEVEELQAQTREPREVI 334
E+ K E +R + I+ +E LR E+E ++ + ++ R+ +
Sbjct: 544 QQEDINNNKKQE--------ERMLKQIENLQETETQLRNELEYVREELKQKRDEV 590
Score = 30.0 bits (66), Expect = 3.4
Identities = 39/187 (20%), Positives = 85/187 (45%), Gaps = 16/187 (8%)
Query: 166 KKRLQQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQ 225
+K++ L ++ E E K K LE+ +++N EKT+ + L ++ ++ + + +
Sbjct: 265 EKQVSLLLIQITEKENKMKDLTFLLEESRDKVNQLEEKTKLQSENLKQSIEKQHHL-TKE 323
Query: 226 ISTLMRQLQQVKDSQQDELDDLGEMRRKVLESLSDK-----IQKKKKKILSSVVAE---T 277
+ + LQ+ +Q+ +DL + + + +K K + S VV E T
Sbjct: 324 LEDIKVSLQRSVSTQKALEEDLQIATKTICQLTEEKETQMEESNKARAAHSFVVTEFETT 383
Query: 278 QRPYEEAL---LQKMWESQDFLKC----MQRFREFIDQFEENMPVLRAEVEELQAQTREP 330
EE L Q++ +++D LK +Q+ +++ + E+EEL+ E
Sbjct: 384 VCSLEELLRTEQQRLEKNEDQLKILTMELQKKSSELEEMTKLTNNKEVELEELKKVLGEK 443
Query: 331 REVIFED 337
+++E+
Sbjct: 444 ETLLYEN 450
Score = 30.0 bits (66), Expect = 3.4
Identities = 24/85 (28%), Positives = 43/85 (50%), Gaps = 2/85 (2%)
Query: 122 LSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRLQQLKSELQ-EWE 180
+ K + + I+E ++ L+ ++ Q+Q +L ++I + K L +K +L+ E E
Sbjct: 714 MEKHKHQYDKIIEERDSELGLY-KSKEQEQSSLRASLEIELSNLKAELLSVKKQLEIERE 772
Query: 181 EKKKCKMSYLEQQAEQLNAKIEKTQ 205
EK+K K E A K +KTQ
Sbjct: 773 EKEKLKREAKENTATLKEKKDKKTQ 797
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 49.7 bits (117), Expect = 4e-06
Identities = 57/250 (22%), Positives = 113/250 (45%), Gaps = 20/250 (8%)
Query: 101 MKTSLRSGRAALRELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDI 160
++ S + R+ EL +N + + + +ET++ + + L +Q I
Sbjct: 1470 LEASQKESRSLSTELFKVKNVYEE-SLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHE 1528
Query: 161 LEYSNKKRLQQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYS 220
LE KK+++Q K E+Q E+ + + + E KI + Q E+N + + +D + +
Sbjct: 1529 LE-KIKKQVEQEKCEIQAALEEAEASLEHEE-------GKILRIQLELNQVKSEVDRKIA 1580
Query: 221 IKSVQISTLMRQLQQVKDSQQDELD-------DLGEMRRKVLESLSD-KIQKKKKKILSS 272
K +I L R +V ++ Q LD D +++K+ L++ +IQ L++
Sbjct: 1581 EKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAA 1640
Query: 273 VVAETQRPYEEALLQKMWESQDFLKCMQRFREFIDQFEENMPVLRAEVEELQA---QTRE 329
R + L + D L+ + +E + E +L+AE+EEL A QT
Sbjct: 1641 ESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTER 1700
Query: 330 PREVIFEDVL 339
R++ +++L
Sbjct: 1701 SRKIAEQELL 1710
Score = 40.4 bits (93), Expect = 0.002
Identities = 42/220 (19%), Positives = 102/220 (46%), Gaps = 5/220 (2%)
Query: 112 LRELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKR--L 169
+ +L + L + +++ ++ +Q E+ + +A + + + + LE K R L
Sbjct: 992 IAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDL 1051
Query: 170 QQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQISTL 229
++ K +L+ + + +E +QL+ K+EK + E++ L + ++ E +++ +Q+
Sbjct: 1052 ERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVE-IQLQKK 1110
Query: 230 MRQLQQVKDSQQDELDDLGEMRRKVLESLSDKIQKKKKKILSSVVAETQRPYEEALLQKM 289
+++LQ + +E++ R K + SD + ++ ++I + + L K
Sbjct: 1111 IKELQARIEELGEEIEAERASRAKAEKQRSD-LSRELEEISERLEEAGGATSAQVELNKK 1169
Query: 290 WESQDFLKCMQRFREFIDQFEENMPVLRAEVEELQAQTRE 329
E+ +F K + E Q E + LR + + A+ E
Sbjct: 1170 REA-EFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGE 1208
Score = 40.4 bits (93), Expect = 0.002
Identities = 35/219 (15%), Positives = 93/219 (42%), Gaps = 15/219 (6%)
Query: 118 RENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRLQQLKSELQ 177
R N L EL T+++ E S + + LL + + + ++ L K +L+
Sbjct: 1680 RANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLL-----HTQNTSLINTKKKLE 1734
Query: 178 EWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQISTLMRQLQQVK 237
+ + ++ + Q++ K +K + ++ + E S + + + L+Q
Sbjct: 1735 NDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDT-SAHLERMKKNLEQTV 1793
Query: 238 DSQQDELDDLGEMRRKVLESLSDKIQKKKKKILSSVVAETQ---------RPYEEALLQK 288
Q LD+ ++ K + K++ + +++ V E + R +E + +
Sbjct: 1794 KDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKEL 1853
Query: 289 MWESQDFLKCMQRFREFIDQFEENMPVLRAEVEELQAQT 327
+++++ K + R ++ +D+ + + + + EE + Q+
Sbjct: 1854 TYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQS 1892
Score = 38.1 bits (87), Expect = 0.012
Identities = 44/215 (20%), Positives = 105/215 (48%), Gaps = 35/215 (16%)
Query: 106 RSGRAALRELRSREN-----FLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDI 160
+ G+A L+ S+ N + +K + I+ +E+E + + LQ+ + ++
Sbjct: 1354 QEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKK-KLAQRLQEAEEHVEAVNA 1412
Query: 161 LEYSNKKRLQQLKSELQEWE-------------EKKKCK----MSYLEQQAEQLNAKIEK 203
S +K Q+L++E+++ +KK+ +S +Q+ E+ A++E
Sbjct: 1413 KCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEA 1472
Query: 204 TQEEVNFLSTYMDHEYSIKSV------QISTLMRQLQQVKDSQQDELDDLGEMRRKV--L 255
+Q+E LST + + +K+V Q+ TL R+ + ++ D + + E +++ L
Sbjct: 1473 SQKESRSLSTEL---FKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHEL 1529
Query: 256 ESLSDKIQKKKKKILSSV-VAETQRPYEEALLQKM 289
E + +++++K +I +++ AE +EE + ++
Sbjct: 1530 EKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRI 1564
Score = 37.0 bits (84), Expect = 0.028
Identities = 58/275 (21%), Positives = 110/275 (40%), Gaps = 50/275 (18%)
Query: 106 RSGRAALRELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSN 165
RS + EL+++E +L +L ++ + R L ++D L + + + ++
Sbjct: 1253 RSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQL-DEKDALVSQLSRSKQAS 1311
Query: 166 KKRLQQLKSELQEWEEKKKCKMSYL------------EQQAEQLNAKIE----------- 202
+++++LK +L+E E K K +++ EQ E+ K E
Sbjct: 1312 TQQIEELKHQLEE-ETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSE 1370
Query: 203 ----KTQEEVNFLSTYMDHEYSIKSV------------QISTLMRQLQQVKDSQQDELDD 246
+T+ E + + + E + K + ++ L++ K Q+E++D
Sbjct: 1371 VAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVED 1430
Query: 247 --LGEMRRKVLESLSDKIQKKKKKILS---SVVAETQRPYEEALLQKMWESQDFLKCMQR 301
L R + DK Q+ K+LS ETQ E + + S + K
Sbjct: 1431 LMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNV 1490
Query: 302 FREFIDQFEENMPVLRAEVEELQAQTREPREVIFE 336
+ E +DQ E LR E + LQ + + E I E
Sbjct: 1491 YEESLDQLE----TLRRENKNLQQEISDLTEQIAE 1521
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 49.3 bits (116), Expect = 5e-06
Identities = 51/253 (20%), Positives = 124/253 (49%), Gaps = 17/253 (6%)
Query: 108 GRAALRELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKK 167
G + + ++ + L+ L + L E +E+E ++ L +Q++ +++L KK
Sbjct: 1409 GELKVAQGKALQENLALLTQTLAEREEEVETLRG-QIQELEKQREMQKAALELLSLDLKK 1467
Query: 168 RLQQLKSELQEWEEKKKCK--MSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQ 225
R Q++ + ++ +E +KC+ + +L ++ K+ +E++ L + + ++ Q
Sbjct: 1468 RNQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQ 1527
Query: 226 ISTLMRQLQQVKDSQQDELDDLGEMRRKVLESLSDKIQKK------KKKILSSVVA--ET 277
+ L ++ Q + +SQ+ ++ DL + + LE L+ ++++ ++K++ + ET
Sbjct: 1528 LLELEKKDQMI-ESQRGQVQDL-KKQLVTLECLALELEENHHKMECQQKLIKELEGQRET 1585
Query: 278 QRPYEEALLQKMWESQDFLKCMQRFREFIDQFEENMPVLRAEVEELQAQTREPREVIFED 337
QR AL + ++ + +Q I E + VL E++E + + RE I E+
Sbjct: 1586 QR---VALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQI-EE 1641
Query: 338 VLLRRPKCTPDMD 350
+ ++ T D++
Sbjct: 1642 LQRQKEHLTQDLE 1654
Score = 45.4 bits (106), Expect = 8e-05
Identities = 52/252 (20%), Positives = 116/252 (46%), Gaps = 35/252 (13%)
Query: 93 KMHAKIWLMKTSLRSGRAALRELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQD 152
++H + +++ LR RA L+ + ++ REL++ +E + H++A + +
Sbjct: 1317 ELHETMASLQSRLR--RAELQRMEAQGE------RELLQAAKENLTAQVEHLQAAVVEAR 1368
Query: 153 TLATIIDILEYSNKKRLQQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLS 212
A+ ILE + LK + +E E +++ + L++Q E A+ + QE + L+
Sbjct: 1369 AQASAAGILEEDLRTARSALKLKNEEVESERE-RAQALQEQGELKVAQGKALQENLALLT 1427
Query: 213 TYMDHEYSIKSVQISTLMRQLQQVKDSQQDELDDLGEMRRKVLESLSDKIQKKKKKILSS 272
+ + + ++ TL Q+Q EL+ EM++ LE LS ++K+ +++
Sbjct: 1428 QTL----AEREEEVETLRGQIQ--------ELEKQREMQKAALELLSLDLKKRNQEV--- 1472
Query: 273 VVAETQRPYEEALLQKMWESQDFLKCMQRFREFIDQFEENMPVLRAEVEELQAQTREPRE 332
+ +++ E + ++ + + E+ + V R ++ EL+ + RE +
Sbjct: 1473 ----------DLQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQREQIRELE-KDRETQR 1521
Query: 333 VIFEDVLLRRPK 344
+ E LL K
Sbjct: 1522 NVLEHQLLELEK 1533
Score = 42.0 bits (97), Expect = 9e-04
Identities = 45/219 (20%), Positives = 86/219 (39%), Gaps = 24/219 (10%)
Query: 113 RELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRLQQL 172
+E + +E L++ +E ++E + + + ++A+ + + LA + L S K+ L+
Sbjct: 715 QEAKRQEEVLARAVQEKEALVRE-KAALEVRLQAVERDRQDLAEQLQGLS-SAKELLESS 772
Query: 173 KSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQISTLMRQ 232
E Q+ + LE Q + + E Q EV L +D E S + RQ
Sbjct: 773 LFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQ 832
Query: 233 LQQVKDSQQDELDDLGEMRRKVLESLSDKIQKKKKKILSSVVAETQRPYEEALLQKMWES 292
L Q + + L+ K + L +K +K++ W
Sbjct: 833 LAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERS----------------------WHQ 870
Query: 293 QDFLKCMQRFREFIDQFEENMPVLRAEVEELQAQTREPR 331
Q+ K ++ + E + + E+E +QAQ E R
Sbjct: 871 QELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEER 909
Score = 40.8 bits (94), Expect = 0.002
Identities = 49/279 (17%), Positives = 117/279 (41%), Gaps = 32/279 (11%)
Query: 75 CQPKNPRELHRRRKLDPGKMHAKIWLMKTSLRSGRAALRELRSRENFLSKLNRELIETIQ 134
CQ K +EL +R+ + ++ + +A ++ E+ + L REL E Q
Sbjct: 1571 CQQKLIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQ 1630
Query: 135 EMENSTTLHVRALLQQQDTLATIIDILEYSNKKRLQQLKSELQEWEEKKKCKMSYLEQQA 194
E+++ + L +Q++ L ++ + L K +Q E+++ + LE+
Sbjct: 1631 EVKSQRE-QIEELQRQKEHLTQDLE----RRDQELMLQKERIQVLEDQRTRQTKILEEDL 1685
Query: 195 EQLNAKIEKTQEEVNFLSTYMDHEY------------SIKSVQISTLMRQLQQVKDSQQD 242
EQ+ + + E+ M S++ +++ ++R ++ + QQ+
Sbjct: 1686 EQIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKL--ILRDKEKEVECQQE 1743
Query: 243 ELDDLGEMRRKVLESLSDKIQKKKKKILSSVVAETQRPYEEALLQKMWE---------SQ 293
+ +L E++ + L ++Q +K+ + + +QR E +LQ+ + Q
Sbjct: 1744 HIHELQELK----DQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQ 1799
Query: 294 DFLKCMQRFREFIDQFEENMPVLRAEVEELQAQTREPRE 332
+ + + Q ++ + L+ E ++ Q Q +E
Sbjct: 1800 SLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKE 1838
Score = 37.0 bits (84), Expect = 0.028
Identities = 54/226 (23%), Positives = 99/226 (43%), Gaps = 42/226 (18%)
Query: 125 LNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRLQQLKSELQE---WE- 180
L EL + E R L Q + T ++ + +++K + QL+ + ++ W
Sbjct: 811 LKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQ 870
Query: 181 ------------EKKKCKMSYLEQQAE----QLNAKIEKTQEEVNFLSTYMDHEYSIKSV 224
EK + +M EQQ E Q + E+TQ E ++ E S+
Sbjct: 871 QELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSL 930
Query: 225 QISTLMRQLQQVKDSQQDELDDLGEMRRKVLESLSDKIQKKKKK----ILSSVVAETQRP 280
+ TL++ +++ D+ Q L +R+ + K+QK K++ IL + + E QR
Sbjct: 931 -LETLLQTQKELADASQ----QLERLRQDM------KVQKLKEQETTGILQTQLQEAQRE 979
Query: 281 YEEALLQKMWESQDFLKCMQRFREFIDQFEENMPVLRAEVEELQAQ 326
+EA Q +D L +Q E ++ M L+ +VE+L++Q
Sbjct: 980 LKEAARQ----HRDDLAALQ--EESSSLLQDKMD-LQKQVEDLKSQ 1018
Score = 35.0 bits (79), Expect = 0.10
Identities = 42/225 (18%), Positives = 98/225 (43%), Gaps = 17/225 (7%)
Query: 115 LRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRLQQLKS 174
LR +E + + +E I +QE+++ ++ L ++ + ++ ++ + L+
Sbjct: 1731 LRDKEKEV-ECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLS----QREQEIVVLQQ 1785
Query: 175 ELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFL------STYMDHEYSIKSVQIST 228
+LQE E+ + K L+ Q ++ + + +E+ L + + K+ +
Sbjct: 1786 QLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQG 1845
Query: 229 LMRQLQQVKDSQQDELDDLGEMRRKVLESLSDKIQKKKKKILSSVVAETQ---RPYEEAL 285
+ Q + EL D E R++ E L+ ++ ++ + L V+ + + R E+AL
Sbjct: 1846 ALEQAHMTLKERHGELQDHKEQARRLEEELA--VEGRRVQALEEVLGDLRAESREQEKAL 1903
Query: 286 LQKMWE-SQDFLKCMQRFREFIDQFEENMPVLRAEVEELQAQTRE 329
L + ++ + R D + + VL+ +EL+A E
Sbjct: 1904 LALQQQCAEQAQEHEVETRALQDSWLQAQAVLKERDQELEALRAE 1948
Score = 32.3 bits (72), Expect = 0.68
Identities = 33/170 (19%), Positives = 76/170 (44%), Gaps = 20/170 (11%)
Query: 173 KSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLST----YMDHEYSI------K 222
K+ELQ+ + ++ ++Q E I+ +E V L T M+HE S+ +
Sbjct: 278 KAELQDRVTELSALLTQSQKQNEDYEKMIKALRETVEILETNHTELMEHEASLSRNAQEE 337
Query: 223 SVQISTLMRQLQQVKDSQQDEL------DDLGEMRRKVLESLSDKIQKKKKKILSSVVAE 276
+ + +++ + QV + D + ++ E+ + + K ++ SV+
Sbjct: 338 KLSLQQVIKDITQVMVEEGDNIAQGSGHENSLELDSSIFSQFDYQDADKALTLVRSVLTR 397
Query: 277 TQRPYEEALLQKMWESQDFLKCMQRFREFIDQFEENMPVLRAEVEELQAQ 326
++ ++ L Q++ Q+ + +Q+ DQ+EE LR +++L +
Sbjct: 398 RRQAVQD-LRQQLAGCQEAVNLLQQQH---DQWEEEGKALRQRLQKLTGE 443
Score = 30.4 bits (67), Expect = 2.6
Identities = 54/255 (21%), Positives = 102/255 (40%), Gaps = 39/255 (15%)
Query: 114 ELRSRENFLSKLNRELIETIQEMENSTT------LHVRALLQQQDTLATIIDILEYSNKK 167
E R +E L L ++ E QE E T L +A+L+++D + S++
Sbjct: 1895 ESREQEKALLALQQQCAEQAQEHEVETRALQDSWLQAQAVLKERDQELEALRAESQSSRH 1954
Query: 168 -------RLQQLKSELQEWEEKKKCKMSYLEQQAE----------QLNAKIEKTQEEVNF 210
R + L+ L + + K +L +QAE L A ++ Q
Sbjct: 1955 QEEAARARAEALQEALGKAHAALQGKEQHLLEQAELSRSLEASTATLQASLDACQAHSRQ 2014
Query: 211 LSTYM---DHEYSIKSVQISTLMRQLQQVKDSQQDELDDLGEMRRKVLESLSDKIQKKKK 267
L + + E + ++ ++QLQQ + +EL E + + +SL+ ++Q+
Sbjct: 2015 LEEALRIQEGEIQDQDLRYQEDVQQLQQALAQRDEELRHQQEREQLLEKSLAQRVQENMI 2074
Query: 268 KILSSVVAETQRPYEEALLQKMWESQDFLKCMQRFREFID----QFEENMPVL------- 316
+ ++ E + L Q + E Q L Q+ +E ++ Q N+ L
Sbjct: 2075 QEKQNLGQEREEEEIRGLHQSVRELQ--LTLAQKEQEILELRETQQRNNLEALPHSHKTS 2132
Query: 317 RAEVEELQAQTREPR 331
E + L+ + EPR
Sbjct: 2133 PMEEQSLKLDSLEPR 2147
Score = 28.5 bits (62), Expect = 9.8
Identities = 45/257 (17%), Positives = 106/257 (41%), Gaps = 36/257 (14%)
Query: 113 RELRSRENFLSKLNRELI---ETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRL 169
R++ LS+ +E++ + +QE L ++L Q D + + + L
Sbjct: 1764 RKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRD-QELEAL 1822
Query: 170 QQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEV---NFLSTYMDHEYSIKSVQI 226
QQ + + Q EE+ K K L+ EQ + +++ E+ + ++ E +++ ++
Sbjct: 1823 QQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRV 1882
Query: 227 STLMRQLQQVKDSQQDELDDLGEMRRKVLESLSD----------------KIQKKKKKIL 270
L L ++ +++ L ++++ E + + K++ + L
Sbjct: 1883 QALEEVLGDLRAESREQEKALLALQQQCAEQAQEHEVETRALQDSWLQAQAVLKERDQEL 1942
Query: 271 SSVVAETQ---------RPYEEALLQKMWESQDFLKCMQRF----REFIDQFEENMPVLR 317
++ AE+Q R EAL + + ++ L+ ++ E E + L+
Sbjct: 1943 EALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLEQAELSRSLEASTATLQ 2002
Query: 318 AEVEELQAQTREPREVI 334
A ++ QA +R+ E +
Sbjct: 2003 ASLDACQAHSRQLEEAL 2019
>gi|81295809 pericentrin [Homo sapiens]
Length = 3336
Score = 49.3 bits (116), Expect = 5e-06
Identities = 48/218 (22%), Positives = 103/218 (47%), Gaps = 29/218 (13%)
Query: 114 ELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRLQQLK 173
+L S+ + LN +L +M+NS T L++++T +I Y+ +++LK
Sbjct: 1668 DLESKNEEILHLNLKL-----DMQNSQTAVSLRELEEENTSLKVI----YTRSSEIEELK 1718
Query: 174 SELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQISTLMRQL 233
+ ++ +E +K ++ EQL+ IEK Q E++ + + + + Q +L +L
Sbjct: 1719 ATIENLQENQKRLQKEKAEEIEQLHEVIEKLQHELSLMGPVV---HEVSDSQAGSLQSEL 1775
Query: 234 QQVKDSQQDELDDLGEMRRKVLESLSDKIQKKKKKILSSVVAETQRPYEEAL--LQKMWE 291
G R + L+ + + K+ LS ++A+ +R + +AL LQ+ +
Sbjct: 1776 L---------CSQAGGPRGQALQG-ELEAALEAKEALSRLLADQERRHSQALEALQQRLQ 1825
Query: 292 SQDFLKCMQRFREFIDQFEENMPVLRAEVEELQAQTRE 329
+ +Q + + E N+ + AEVE++ ++ +E
Sbjct: 1826 GAEEAAELQ-----LAELERNVALREAEVEDMASRIQE 1858
Score = 43.1 bits (100), Expect = 4e-04
Identities = 63/266 (23%), Positives = 111/266 (41%), Gaps = 46/266 (17%)
Query: 102 KTSLRSGRAALRELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDT-LATIIDI 160
+T +R ++ L E R + +L+R L E QE+ L +R++L ++ L +
Sbjct: 2603 QTVVRDLKSDLCESRQKSE---QLSRSLCEVQQEV-----LQLRSMLSSKENELKAALQE 2654
Query: 161 LEYSNKKRLQQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYS 220
LE S + + + L+S+L+E + + + S + E+L A +E + + + L + HE +
Sbjct: 2655 LE-SEQGKGRALQSQLEEEQLRHLQRESQSAKALEELRASLETQRAQSSRLCVALKHEQT 2713
Query: 221 IKS---------------------VQISTLMRQLQQVKDSQQDELDDLGEMRRKVLESLS 259
K Q+S L + L K S+ EL + R + E LS
Sbjct: 2714 AKDNLQKELRIEHSRCEALLAQERSQLSELQKDLAAEK-SRTLELSEALRHERLLTEQLS 2772
Query: 260 DKIQK--------------KKKKILSSVVAETQRPYEEALLQKMWESQDFLKCMQRFREF 305
+ Q+ +K K S V + Q E+ Q + Q Q+ E
Sbjct: 2773 QRTQEACVHQDTQAHHALLQKLKEEKSRVVDLQAMLEKVQQQALHSQQQLEAEAQKHCEA 2832
Query: 306 IDQFEENMPVLRAEVEELQAQTREPR 331
+ + +E L++ VE L Q RE R
Sbjct: 2833 LRREKEVSATLKSTVEALHTQKRELR 2858
Score = 40.0 bits (92), Expect = 0.003
Identities = 58/235 (24%), Positives = 98/235 (41%), Gaps = 43/235 (18%)
Query: 108 GRAALRELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKK 167
G A + +RE L K +L + E ALL Q + ILE ++
Sbjct: 1393 GEATATDAEAREAALRKEVEDLTKEQSETRKQAEKDRSALLSQ-------MKILESELEE 1445
Query: 168 RLQQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQIS 227
+L Q + ++ E ++ LEQQ L+ + ++ ++ + +HE +I
Sbjct: 1446 QLSQHRGCAKQAEA-----VTALEQQVASLDKHLRNQRQFMDEQAAEREHEREEFQQEIQ 1500
Query: 228 TLMRQLQQV--------KDSQQDELDDLGEMRRKVLESLSDKIQKKKKKILSSVVAETQR 279
L QL+Q +DSQQ LD GE +E L K+++K +
Sbjct: 1501 RLEGQLRQAAKPQPWGPRDSQQAPLD--GE-----VELLQQKLREKLDE----------- 1542
Query: 280 PYEEALLQKMWESQDFLKCMQRFREFIDQFEENMPVLRAEVEELQAQTREPREVI 334
+ E +QK ES D MQ E I + EE +R +V +LQ + + + ++
Sbjct: 1543 -FNELAIQK--ESADRQVLMQ--EEEIKRLEEMNINIRKKVAQLQEEVEKQKNIV 1592
Score = 39.3 bits (90), Expect = 0.006
Identities = 56/242 (23%), Positives = 106/242 (43%), Gaps = 39/242 (16%)
Query: 101 MKTSLRSGRAALRELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQ--QQDTLATII 158
++ SL + A EL L K + ++EM NS ALLQ QQ L +
Sbjct: 250 LRLSLSNMHTAQLELTQAN--LQKEKETALTELREMLNSRRAQELALLQSRQQHELELLR 307
Query: 159 DILEYSNKKRLQQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHE 218
+ ++ + + E E +EK + +M + NA+I KT +E D E
Sbjct: 308 EQHAREKEEVVLRCGQEAAELKEKLQSEM--------EKNAQIVKTLKE--------DWE 351
Query: 219 YSIKSVQISTLMRQLQQVKDSQQDELD-----DLGEMRRKVLESLSDKIQKKKKKILSSV 273
S K + + L ++L S+ ++L +L E R ++ + DK Q ++
Sbjct: 352 -SEKDLCLENLRKELSAKHQSEMEDLQNQFQKELAEQRAELEKIFQDKNQAER------- 403
Query: 274 VAETQRPYEEALLQKMWES--QDFLKCMQ----RFREFIDQFEENMPVLRAEVEELQAQT 327
+ +A ++K+ E + +C++ +F+E + + + L+A E+L+AQ+
Sbjct: 404 ALRNLESHHQAAIEKLREDLQSEHGRCLEDLEFKFKESEKEKQLELENLQASYEDLKAQS 463
Query: 328 RE 329
+E
Sbjct: 464 QE 465
Score = 38.1 bits (87), Expect = 0.012
Identities = 49/233 (21%), Positives = 101/233 (43%), Gaps = 30/233 (12%)
Query: 114 ELRSRENFLSKLNRELIETIQEMENSTTLHVR-----ALLQQQDTLATIIDILEYSNKKR 168
+L + L +L + +I +++ + H+R +LL + L + + N+++
Sbjct: 2480 DLGGHSSLLERLEK-IIREQGDLQEKSLEHLRLPDRSSLLSEIQALRAQLRMTHLQNQEK 2538
Query: 169 LQQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIE--------------KTQEEVNFLSTY 214
LQ L++ L E + + L +Q E L K+E + QE+ N +
Sbjct: 2539 LQHLRTALTSAEARGSQQEHQLRRQVELLAYKVEQEKCIAGDLQKTLSEEQEKANSVQKL 2598
Query: 215 MDHEYSIKSVQISTLMRQLQQVKDSQQDELDDLGEMRRKVLESLSDKIQKKKKKILSSVV 274
+ E ++ + L L + + + L E++++VL+ S K+ + +
Sbjct: 2599 LAAEQTV----VRDLKSDLCESRQKSEQLSRSLCEVQQEVLQLRSMLSSKENELKAALQE 2654
Query: 275 AETQRPYEEALLQKMWESQDFLKCMQRFREFIDQFEENMPVLRAEVEELQAQT 327
E+++ AL ++ E Q L+ +QR + EE LRA +E +AQ+
Sbjct: 2655 LESEQGKGRALQSQLEEEQ--LRHLQRESQSAKALEE----LRASLETQRAQS 2701
Score = 36.2 bits (82), Expect = 0.047
Identities = 41/171 (23%), Positives = 79/171 (46%), Gaps = 10/171 (5%)
Query: 141 TLHVRALLQQQDTLATIIDILEYSNKKRLQQLKSELQEWEEKKKCKMSYLEQQAEQLNAK 200
T H L Q L I++L+ N+ +L+ E + ++ +K K + +E ++LN
Sbjct: 675 TEHKVQLSLLQTELKEEIELLKIENRNLYGKLQHETRLKDDLEKVKHNLIEDHQKELNNA 734
Query: 201 IEKTQ---EEVNFLST---YMDHEYSIKSVQISTLM-RQLQQVKDSQQDELDDLGEMRRK 253
+KT+ +E T M E ++ + TLM +L++ +S++ + + E+R
Sbjct: 735 KQKTELMKQEFQRKETDWKVMKEELQREAEEKLTLMLLELREKAESEKQTIINKFELREA 794
Query: 254 VLESLSDKIQKKKKKILSSVVAETQRPYEEALLQKMWESQDFLKCMQRFRE 304
+ L D ++ +IL + T++ L++ S D L C Q RE
Sbjct: 795 EMRQLQD---QQAAQILDLERSLTEQQGRLQQLEQDLTSDDALHCSQCGRE 842
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 48.9 bits (115), Expect = 7e-06
Identities = 54/224 (24%), Positives = 101/224 (45%), Gaps = 24/224 (10%)
Query: 113 RELRSRENFLSKLNRELI-----------ETIQEMENSTTLHVRALLQQQDTLATIIDIL 161
+E++ EN LS+ E I +T Q ME T+ + +QQ+ L + + +
Sbjct: 2408 KEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIK-KENIQQKAQLDSFVKSM 2466
Query: 162 EYSNKKRLQQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDH---- 217
R ++ + Q+ EE+ + +Q ++ A+ K +EE+ L ++MD
Sbjct: 2467 SSLQNDR-DRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSE 2525
Query: 218 --EYSIKSVQISTLMRQLQQVKDSQQDELDDLGEMRRKVLESLSDKIQKKKKKILSSVVA 275
+ + +Q + Q+ +KDSQQ +L ++ + K LE+ K+++K K+ S
Sbjct: 2526 NAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKE--SEEAN 2583
Query: 276 ETQRPYEEALLQKMWESQDFLKCMQRFREFIDQFEENMPVLRAE 319
E R AL + E QD K ++ + I Q + L+ E
Sbjct: 2584 EDLRRSFNALQE---EKQDLSKEIESLKVSISQLTRQVTALQEE 2624
Score = 42.7 bits (99), Expect = 5e-04
Identities = 54/227 (23%), Positives = 111/227 (48%), Gaps = 29/227 (12%)
Query: 130 IETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRLQQLKSELQEWEEKKKCKMSY 189
IE+++ + + +H +L Q+ ++ I LE+ + LQ ELQ+ KK+ +SY
Sbjct: 1353 IESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHL--RELQPKLDELQKLISKKEEDVSY 1410
Query: 190 LEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQISTLMRQLQQVKDSQQDELDDLGE 249
L Q + A + K Q E+ ++ E IK++ M+ + + +Q ++ +L E
Sbjct: 1411 LSGQLSEKEAALTKIQTEI------IEQEDLIKALHTQLEMQAKEHDERIKQLQV-ELCE 1463
Query: 250 MRRKVLESLSDKIQKKKKKILSSVVAETQRPYEEALLQK---MWESQDFLKCMQRFREFI 306
M++K E + ++ + K+ + QR + AL+ + + E++ + + R I
Sbjct: 1464 MKQKP-EEIGEESRAKQ---------QIQRKLQAALISRKEALKENKSLQEELSLARGTI 1513
Query: 307 DQFEENMPVLRAEVE-ELQAQTREPREVIFEDVLLR--RPKCTPDMD 350
++ +++ A+VE ++ AQ +E V+ LL+ R K +MD
Sbjct: 1514 ERLTKSL----ADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMD 1556
Score = 41.2 bits (95), Expect = 0.001
Identities = 59/267 (22%), Positives = 108/267 (40%), Gaps = 24/267 (8%)
Query: 76 QPKNPRELHRRRKLDPGKMHAKIWLMKTSLRSGRAALRELRSRENFLSKLNRELIE---- 131
+P+ E R ++ K+ A + K +L+ ++ EL + +L + L +
Sbjct: 1467 KPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQ 1526
Query: 132 -TIQEMENSTTLHVRALLQQQ-DTLATIIDILEYSNKKRLQQLKSELQEWEEKKKCKMSY 189
+ Q E T L ALLQ++ D L T +D N Q L S E K +
Sbjct: 1527 VSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLEN----QSLSSSC----ESLKLALEG 1578
Query: 190 LEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQISTLMRQLQQVKDSQQDELDDLGE 249
L + E+L +IE + ST ++ + L++ + V + E
Sbjct: 1579 LTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNE--------AE 1630
Query: 250 MRRKVLESLSDKIQKKKKKILSSVV--AETQRPYEEALLQKMWESQDFLKCMQRFREFID 307
+ V+E++ + Q+ K+ S+ ET++ +EA + + K + ++ I
Sbjct: 1631 RIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKIL 1690
Query: 308 QFEENMPVLRAEVEELQAQTREPREVI 334
+ EE LRAEV +E E +
Sbjct: 1691 ELEEENDRLRAEVHPAGDTAKECMETL 1717
Score = 40.0 bits (92), Expect = 0.003
Identities = 57/261 (21%), Positives = 109/261 (41%), Gaps = 27/261 (10%)
Query: 86 RRKLDPGKMHAKIWLMKTSLRSGRAALRELRSRENFLSKLNRELIETIQEMENSTTLHVR 145
R LDP ++H ++ + +++ R + +L EL + I++ +
Sbjct: 27 RAPLDP-ELH-----QESDMEFNNTTQEDVQERLAYAEQLVVELKDIIRQKDVQLQQKDE 80
Query: 146 ALLQQQDTLATIIDILEYSNKKRLQQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQ 205
AL +++ I L+ K +L L ++E + + + Q EQL+ K +K+
Sbjct: 81 ALQEERKAADNKIKKLKLHAKAKLTSLNKYIEEMKAQGGTVLPTEPQSEEQLS-KHDKSS 139
Query: 206 EEVNFLSTYMDHEYSIKSVQISTLMRQLQQVKDSQ----QDELDDLGEMRRKVLES---- 257
E + H+ K ISTL QL Q + Q E+++ M++++ E
Sbjct: 140 TEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEKEEFI 199
Query: 258 ---LSDKIQKKKKKILSSVVAETQ-------RPYEEALLQKMWESQDFLKCMQRFREFID 307
+ Q + ++ VV E R +E+ LLQ + ++ + Q+ R
Sbjct: 200 STLQAQLSQTQAEQAAQQVVREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQR 259
Query: 308 QFEENMPVL--RAEVEELQAQ 326
+ EE+ L RA+V +L Q
Sbjct: 260 KLEEHEESLVGRAQVVDLLQQ 280
Score = 37.0 bits (84), Expect = 0.028
Identities = 58/277 (20%), Positives = 123/277 (44%), Gaps = 42/277 (15%)
Query: 79 NPRELHRRRKLDPGKMHAKIWLMKTSLRSGRAALRELRSRENFLSKLNRELIETIQEMEN 138
N E R+R+LD A L+ + S E +S++ + L EL + +
Sbjct: 772 NLAEAERQRRLDYESQTAHDNLLTEQIHSLSI---EAKSKDVKIEVLQNELDDVQLQFSE 828
Query: 139 STTLHVRALLQQQDTLATIIDILEYSNKKRLQQLKSELQEWEE---KKKCKMSYLEQ--- 192
+TL +R+L Q + ++LE +R++ + S+++E + +K+ +++ ++Q
Sbjct: 829 QSTL-IRSLQSQLQNKES--EVLE--GAERVRHISSKVEELSQALSQKELEITKMDQLLL 883
Query: 193 ----QAEQLNAKIEKTQEEVNFLSTYM--------DHEYSIKSVQISTLMRQL------Q 234
E L IE+ ++V +S M + ++S+ V+I TL QL +
Sbjct: 884 EKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSL-GVEIKTLKEQLNLLSRAE 942
Query: 235 QVKDSQQDELDDLGEMRRKVLESLSDKIQKKKKK------ILSSVVAETQRPYEEALLQK 288
+ K Q +E +++ ++ + +S Q K++ +L + +R + AL+ +
Sbjct: 943 EAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINR 1002
Query: 289 MWESQDFLKCMQRFREFIDQFEENMPVL---RAEVEE 322
Q + + D+ ++ +P+ R EVEE
Sbjct: 1003 KELLQRVSRLEEELANLKDESKKEIPLSETERGEVEE 1039
Score = 37.0 bits (84), Expect = 0.028
Identities = 36/168 (21%), Positives = 80/168 (47%), Gaps = 15/168 (8%)
Query: 102 KTSLRSGRAALRELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDIL 161
+ L S + L + +S + N +L + +Q + S V++ ++Q+D + L
Sbjct: 2074 QAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKES----VKSQMKQKDE--DLERRL 2127
Query: 162 EYSNKKRLQQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSI 221
E + +K L++ K +QE + + + +LE+ ++ + K +EV L +D +
Sbjct: 2128 EQAEEKHLKE-KKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVT- 2185
Query: 222 KSVQISTLMRQLQQVKDSQQDELDDLGEMRRKVLESLSDKIQKKKKKI 269
Q++ + + ++D + +D+ + RK SD IQ K+++I
Sbjct: 2186 ---QLAAFTKSMSSLQDDRDRVIDEAKKWERK----FSDAIQSKEEEI 2226
Score = 36.6 bits (83), Expect = 0.036
Identities = 57/268 (21%), Positives = 116/268 (43%), Gaps = 40/268 (14%)
Query: 122 LSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRLQQLKSELQEWEE 181
L+K ++E ++ +QE +ST + A + +L D + KK ++ +Q EE
Sbjct: 2166 LNKKDKE-VQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEE 2224
Query: 182 K---KKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQISTLMRQLQQVKD 238
+ K+ S L+ Q Q++ +E+ + ++ L +H+ I + T ++ Q+V D
Sbjct: 2225 EIRLKEDNCSVLKDQLRQMSIHMEELKINISRL----EHDKQIWESKAQTEVQLQQKVCD 2280
Query: 239 SQQDE----LDDLGEMR-------------RKVLESLSDKIQ---------KKKKKILSS 272
+ Q E L L E R L+SL D++ K++K L
Sbjct: 2281 TLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEG 2340
Query: 273 VVAETQRPYEEALLQKMWESQDFLKC-MQRFREFIDQFEENMPVLRAEVEELQAQTREPR 331
++ + +EA +Q S + L+ +Q RE + E + + ++ L + E
Sbjct: 2341 IIRQ-----QEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLLSGKEEAI 2395
Query: 332 EVIFEDVLLRRPKCTPDMDVILNIPVEE 359
+V ++ + K +++ +L+ EE
Sbjct: 2396 QVAIAELRQQHDKEIKELENLLSQEEEE 2423
Score = 35.8 bits (81), Expect = 0.062
Identities = 40/168 (23%), Positives = 79/168 (47%), Gaps = 24/168 (14%)
Query: 104 SLRSGRAA-LRELRSRENFLSKLNRELIETIQEMENSTTLH---VRALLQQQDTLATIID 159
SL+S + A E + + L K L+++ + + N V A+ Q++ L +
Sbjct: 1592 SLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLR 1651
Query: 160 ILEYSNK---KRLQQLKSELQEWEEK-------KKCKMSYLEQQAEQLNAKI-------E 202
E + K K+LQ+ + E++E +EK K+ K+ LE++ ++L A++ +
Sbjct: 1652 STEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTAK 1711
Query: 203 KTQEEVNFLSTYMDHEYSIKSVQISTLMRQLQQV---KDSQQDELDDL 247
+ E + + M E ++ TL ++ Q + KDS +E+ DL
Sbjct: 1712 ECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDL 1759
Score = 35.4 bits (80), Expect = 0.080
Identities = 50/237 (21%), Positives = 104/237 (43%), Gaps = 31/237 (13%)
Query: 119 ENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTL---ATIIDILEY---SNKKRLQQL 172
+ L + + +ET EM+ + R L + +++L A ++D+L+ + ++R Q L
Sbjct: 235 DELLQLVTQADVET--EMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQIL 292
Query: 173 KSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQ--ISTLM 230
+LQ+ E + + +E + E+ +EK + EV + + S ++Q + L+
Sbjct: 293 SQQLQQMEAEHNTLRNTVETEREESKILLEKMELEV------AERKLSFHNLQEEMHHLL 346
Query: 231 RQLQQVKDSQQD--------ELDDLGEMRRKVLESLSDKIQKKKKKILSSVVAETQRPYE 282
Q +Q +Q + E EM K LS +QK +++ S+ + +
Sbjct: 347 EQFEQAGQAQAELESRYSALEQKHKAEMEEKTSHILS--LQKTGQELQSA--CDALKDQN 402
Query: 283 EALLQKMWESQDFLKCMQRFREFIDQFEENMPVLRAEVEELQAQTRE-PREVIFEDV 338
LLQ +++ ++ Q ++ DQ ++ + + L Q E + F DV
Sbjct: 403 SKLLQD--KNEQAVQSAQTIQQLEDQLQQKSKEISQFLNRLPLQQHETASQTSFPDV 457
Score = 35.0 bits (79), Expect = 0.10
Identities = 44/193 (22%), Positives = 88/193 (45%), Gaps = 13/193 (6%)
Query: 126 NRELIETIQEMENSTTLHVRALLQQQDTLATIIDIL-EYSNK-KRLQQLKSEL-----QE 178
N+EL+ ++E + L + + L ++ D L + SN ++ ++ K L Q+
Sbjct: 2286 NKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQ 2345
Query: 179 WEEKKKCKMSYLEQQAEQLNAKIEKTQ---EEVNFLSTYMDHEYSIKSVQISTLMRQLQQ 235
+ + K SY EQ L A E T EE+N + S K I + +L+Q
Sbjct: 2346 EADIQNSKFSY-EQLETDLQASRELTSRLHEEINMKEQKIISLLSGKEEAIQVAIAELRQ 2404
Query: 236 VKDSQQDELDDLGEMRRKVLESLSDKIQKKKKKILSSVVAETQRPYEEALLQKMWESQDF 295
D + EL++L + ++ E++ + + KK ++ + ET + ++ +Q+ + F
Sbjct: 2405 QHDKEIKELENL--LSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSF 2462
Query: 296 LKCMQRFREFIDQ 308
+K M + D+
Sbjct: 2463 VKSMSSLQNDRDR 2475
Score = 33.1 bits (74), Expect = 0.40
Identities = 22/80 (27%), Positives = 44/80 (55%), Gaps = 2/80 (2%)
Query: 166 KKRLQQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQ 225
+K +QL+ +LQE +K + +++ L ++++ +++ N L D E S ++
Sbjct: 1170 EKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFD-EQSKENEN 1228
Query: 226 ISTLMRQLQ-QVKDSQQDEL 244
I +RQLQ QV++S +L
Sbjct: 1229 IGDQLRQLQIQVRESIDGKL 1248
Score = 32.0 bits (71), Expect = 0.89
Identities = 37/189 (19%), Positives = 80/189 (42%), Gaps = 19/189 (10%)
Query: 100 LMKTSLRSGRAALRELRSRENFL--------SKLNRELIETIQ--EMENSTTLHVRALLQ 149
L+++ +++ + + EL + L S++ +E +E IQ + E H + L +
Sbjct: 1953 LLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQE 2012
Query: 150 -----QQDTLATIIDILEYSNK-KRLQQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEK 203
QQ+ D + Y K L++ L+ + + + + ++ Q +K
Sbjct: 2013 LLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKK 2072
Query: 204 TQEEVNFLSTYMDHEYSIKSVQIST---LMRQLQQVKDSQQDELDDLGEMRRKVLESLSD 260
Q E+ +D S + ++ L ++LQ K+S + ++ E + LE +
Sbjct: 2073 AQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEE 2132
Query: 261 KIQKKKKKI 269
K K+KK +
Sbjct: 2133 KHLKEKKNM 2141
Score = 29.6 bits (65), Expect = 4.4
Identities = 41/204 (20%), Positives = 83/204 (40%), Gaps = 18/204 (8%)
Query: 102 KTSLRSGRAALRELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDI- 160
+ L+ R L E + E L +++ +T+Q+ N L + + Q + +I
Sbjct: 1070 EVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSN 1129
Query: 161 LEYSNKKRLQQLKSEL----------QEWEEKKKCKMSYLEQQAEQLNAKI-EKTQEEVN 209
+ S+ + +K + + W+ + + K+ LE++ EQL K+ E
Sbjct: 1130 TDASDGDSVALVKETVVISPPCTGSSEHWKPELEEKILALEKEKEQLQKKLQEALTSRKA 1189
Query: 210 FLSTYMDHEYSIKS--VQISTLMRQLQQVKDSQQDELDDLGEMRR----KVLESLSDKIQ 263
L + E ++ Q +LQ+ D Q E +++G+ R +V ES+ K+
Sbjct: 1190 ILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESIDGKLP 1249
Query: 264 KKKKKILSSVVAETQRPYEEALLQ 287
++ S + P +A Q
Sbjct: 1250 STDQQESCSSTPGLEEPLFKATEQ 1273
Score = 28.5 bits (62), Expect = 9.8
Identities = 28/107 (26%), Positives = 49/107 (45%), Gaps = 16/107 (14%)
Query: 169 LQQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQIST 228
L++ S LQ ++ ++ L+QQ Q+N +I E++ L + EY K+
Sbjct: 2879 LKKAMSSLQNDRDRLLKELKNLQQQYLQINQEI----TELHPLKAQL-QEYQDKTKAFQI 2933
Query: 229 LMRQLQQVKDSQQDELDDL-----------GEMRRKVLESLSDKIQK 264
+ +L+Q S Q EL L M+ + L ++SDK Q+
Sbjct: 2934 MQEELRQENLSWQHELHQLRMEKSSWEIHERRMKEQYLMAISDKDQQ 2980
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 48.5 bits (114), Expect = 9e-06
Identities = 46/212 (21%), Positives = 97/212 (45%), Gaps = 21/212 (9%)
Query: 130 IETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRLQQLKSELQEWEEKKKCKMSY 189
+ +QE + HV +L Q + L ++ LE K L++ + LQE + K
Sbjct: 1108 LNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKE-NTFLQEQLVELKMLAEE 1166
Query: 190 LEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKS----------------VQISTLMRQL 233
+++ +L +K++ T EE F S HE S KS +Q+ ++
Sbjct: 1167 DKRKVSELTSKLKTTDEE--FQSLKSSHEKSNKSLEDKSLEFKKLSEELAIQLDICCKKT 1224
Query: 234 QQVKDSQQDELDDLGEMRRKVLESLSDKIQKKKKKILSSVVAETQRPYE-EALLQKMWES 292
+ + +++ +EL ++ + + S Q + K+ +++ +T E EA L+++ E
Sbjct: 1225 EALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEE 1284
Query: 293 QDFLK-CMQRFREFIDQFEENMPVLRAEVEEL 323
Q+ L Q+ +++ E + ++A++E L
Sbjct: 1285 QNTLNISFQQATHQLEEKENQIKSMKADIESL 1316
Score = 46.2 bits (108), Expect = 5e-05
Identities = 41/214 (19%), Positives = 101/214 (47%), Gaps = 14/214 (6%)
Query: 132 TIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRLQQLKSELQEWEEKKKCKMSYLE 191
T++E++ L + ++ + + + + L+ NK R LK E+++ + K + K S LE
Sbjct: 1459 TVKELQIQLELKSKEAYEKDEQINLLKEELDQQNK-RFDCLKGEMEDDKSKMEKKESNLE 1517
Query: 192 QQAEQLNAKIEKTQE-------EVNFLSTYMDHEYSIKSVQISTLMRQLQQVKDSQQDEL 244
+ + A+I + ++ E+ L+ + + K ++ L+++LQ ++ +++
Sbjct: 1518 TELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKD 1577
Query: 245 DDLGEMRRKVLE------SLSDKIQKKKKKILSSVVAETQRPYEEALLQKMWESQDFLKC 298
+ + E K+L S+ +++ KKK++ ++ + E L+ ES+ K
Sbjct: 1578 NRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKL 1637
Query: 299 MQRFREFIDQFEENMPVLRAEVEELQAQTREPRE 332
+ R+ + L +++EE + Q ++ E
Sbjct: 1638 AELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTE 1671
Score = 43.9 bits (102), Expect = 2e-04
Identities = 52/242 (21%), Positives = 101/242 (41%), Gaps = 37/242 (15%)
Query: 100 LMKTSLRSGRAALRELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIID 159
+MK S A L++L +E L++ +EL + +Q E ++ L++ + +
Sbjct: 469 VMKKSSEEQIAKLQKLHEKE--LARKEQELTKKLQTREREFQEQMKVALEKSQS-----E 521
Query: 160 ILEYSNKKRLQQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEY 219
L+ S +K QQ L+E E +KK ++ E + L + E + + L + ++
Sbjct: 522 YLKISQEKE-QQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSL 580
Query: 220 SIKSVQISTLMRQLQQVKDSQQDELDDLGEMRRKVLESL---SDKIQKKKKKILSSVVAE 276
Q L L+ K+ E+ + E + LESL D + +K ++L
Sbjct: 581 QENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVL------ 634
Query: 277 TQRPYEEALLQKMWESQDFLKCMQRFREFIDQFEENM-----PVLRAEVEELQAQTREPR 331
Q + M++ RE +Q +E + + +A +EE+ +T E
Sbjct: 635 ---------------KQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKL 679
Query: 332 EV 333
+V
Sbjct: 680 DV 681
Score = 43.5 bits (101), Expect = 3e-04
Identities = 63/272 (23%), Positives = 118/272 (43%), Gaps = 45/272 (16%)
Query: 65 HFKPTTVVTS----CQPKNPRELHRRRKLDPGKMHAKIWLMKTSLRSGRAALRELRSREN 120
H + T++TS Q + L K+ M K L+ T LR + + +L +
Sbjct: 305 HKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLI-TQLRDAKNLIEQLEQDKG 363
Query: 121 F-LSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRLQQLKSELQEW 179
+++ R++ ET+ EM+ +R+ ++Q T + R Q+ KSE +
Sbjct: 364 MVIAETKRQMHETL-EMKEEEIAQLRSRIKQMTT---------QGEELREQKEKSERAAF 413
Query: 180 EEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQIS------TLMRQL 233
EE +K + +KT+E L MD + IK+++ + +L ++L
Sbjct: 414 EELEKAL------------STAQKTEEARRKLKAEMDEQ--IKTIEKTSEEERISLQQEL 459
Query: 234 QQVKDSQQDELDDLGEMRRKVLESLSDKIQKKKKKILSSVVAETQRPYEEALLQKMWESQ 293
+VK D + E + L+ L +K +K++ L+ + +R ++E + + +SQ
Sbjct: 460 SRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQ 519
Query: 294 -DFLKCMQRFREFIDQFEENMPVLRAEVEELQ 324
++LK I Q +E L E ELQ
Sbjct: 520 SEYLK--------ISQEKEQQESLALEELELQ 543
Score = 43.1 bits (100), Expect = 4e-04
Identities = 60/268 (22%), Positives = 122/268 (45%), Gaps = 48/268 (17%)
Query: 109 RAALRELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKR 168
+ A ++ + EN + + EL +E+E+ L V++ +++ L + D LE + +
Sbjct: 1581 KEAEEKILTLENQVYSMKAELETKKKELEH-VNLSVKS---KEEELKALEDRLESESAAK 1636
Query: 169 LQQLKSE------------LQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMD 216
L +LK + L + EEK++ E +LN K+++ + EV+ L +
Sbjct: 1637 LAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLK 1696
Query: 217 HEYSIKSVQISTLM--RQLQQVKD-SQQDELDDLGEMRRKVLESLS--DKIQKKKKKILS 271
S++S Q TL+ R + V ++Q+E D G +++ E +S + +K+K+L
Sbjct: 1697 ---SVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQ 1753
Query: 272 SVVAETQR----------PYEEALLQ------KMWESQDFLKCMQRFREFIDQFEENMPV 315
V E + Y+E L++ K E Q + +Q E +++ + +
Sbjct: 1754 RVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQ---EELEEKNKKYSL 1810
Query: 316 LRAEVEELQA-----QTREPREVIFEDV 338
+ A+ E + Q ++ E +F+DV
Sbjct: 1811 IVAQHVEKEGGKNNIQAKQNLENVFDDV 1838
Score = 41.2 bits (95), Expect = 0.001
Identities = 46/246 (18%), Positives = 108/246 (43%), Gaps = 39/246 (15%)
Query: 114 ELRSRENFLSKLNRELIETIQEMENSTTLHVR----------------ALLQQQDTLATI 157
EL+ ++ +S L+++L + +++NS +L + LL Q L+
Sbjct: 1361 ELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSFK 1420
Query: 158 IDILEYSNKKRLQQL---KSELQEWEEKKKCKMSYLEQQAEQLNAKIE-------KTQEE 207
+D L L+Q+ ++ EW++K + + + + ++L ++E + E+
Sbjct: 1421 VDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQ 1480
Query: 208 VNFLSTYMDHEYSIKSVQISTLMRQLQQVKDSQQDELDDLGEMRRKVLESLSDKIQKKKK 267
+N L +D + + +++ + + +L +++E L D I +K
Sbjct: 1481 INLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIME-LEDHITQKTI 1539
Query: 268 KILSSVVAETQRPYEEALLQKMWESQDFLKCMQRFREF-------IDQFEENMPVLRAEV 320
+I S + E + Y + QK E ++ ++ +Q F+E + + EE + L +V
Sbjct: 1540 EIES--LNEVLKNYNQ---QKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQV 1594
Query: 321 EELQAQ 326
++A+
Sbjct: 1595 YSMKAE 1600
Score = 38.5 bits (88), Expect = 0.009
Identities = 51/235 (21%), Positives = 108/235 (45%), Gaps = 17/235 (7%)
Query: 110 AALRELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRL 169
A + ++ E L++L ++L++ ++ T V + Q+ + T +D + + +
Sbjct: 809 ATHEQTKAYEEQLAQLQQKLLD-LETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLM 867
Query: 170 QQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQ----EEVNFLSTYMDHEYSIKSVQ 225
QQL+ + E E+K K E + E N + E+T+ E+ N + E K ++
Sbjct: 868 QQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMI--LQMREGQKKEIE 925
Query: 226 ISTLMRQLQQVKDSQQDELDDLGEMRRKVLESLSDKIQKKKKKILSSVVAETQRPYEEAL 285
I T Q K+ L++ E + K E +K+++K K++ ++ + + +EA
Sbjct: 926 ILT---QKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETL--KKKLLDQEAK 980
Query: 286 LQKMWESQDFLKCMQRFREF----IDQFEENMPVLRAEVEELQAQTREPREVIFE 336
L+K E+ L+ Q+ ++F ++ + N + V L+ +E E + E
Sbjct: 981 LKKELEN-TALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTE 1034
Score = 35.4 bits (80), Expect = 0.080
Identities = 50/206 (24%), Positives = 90/206 (43%), Gaps = 15/206 (7%)
Query: 125 LNRE-LIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRLQQLKSELQEWEEKK 183
LN+E LI+ ++ ME S + + + L T +L+ KK+LQ + S+ Q+ K
Sbjct: 134 LNKEQLIQRLRRMERSLSSY----RGKYSELVTAYQMLQ-REKKKLQGILSQSQD---KS 185
Query: 184 KCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQISTLMRQLQQVKDSQQDE 243
+++ L ++ + + QEE + D S+ Q+S L ++L+ D
Sbjct: 186 LRRIAELREELQMDQQAKKHLQEEFDASLEEKDQYISVLQTQVSLLKQRLRN-GPMNVDV 244
Query: 244 LDDLGEMRRKVLESLSDKIQKKKKKILSSVVAETQRPYEEALLQKMWESQDFLKCMQRFR 303
L L ++ + + K + + V T E L Q++ ++ LK R +
Sbjct: 245 LKPLPQLEPQA--EVFTKEENPESDGEPVVEDGTSVKTLETLQQRVKRQENLLK---RCK 299
Query: 304 EFIDQFEENMPVLRAEVEELQAQTRE 329
E I +E +L +E E LQ Q E
Sbjct: 300 ETIQSHKEQCTLLTSEKEALQEQLDE 325
Score = 34.7 bits (78), Expect = 0.14
Identities = 40/168 (23%), Positives = 76/168 (45%), Gaps = 21/168 (12%)
Query: 115 LRSRENFLSKLNRELIETIQEMENSTTLHVRALLQ--QQDTLATIIDILEYSN--KKRLQ 170
+R L++ +EL TI+E N LL+ Q++T + I E + K+ +
Sbjct: 1998 MREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAK 2057
Query: 171 QLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQISTLM 230
+ + L EE+ K+ L+ Q E+L K ++ E+ + +V I L
Sbjct: 2058 RYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQ--------EENPGNDNVTIMELQ 2109
Query: 231 RQLQQ----VKDSQQDELDDLGEMRRKVLESLSDKIQKKKKKILSSVV 274
QL Q + DS+ E + R+ + +L D+++K +K + ++ V
Sbjct: 2110 TQLAQKTTLISDSKLKE-----QEFREQIHNLEDRLKKYEKNVYATTV 2152
Score = 32.3 bits (72), Expect = 0.68
Identities = 38/231 (16%), Positives = 96/231 (41%), Gaps = 17/231 (7%)
Query: 94 MHAKIWLMKTSLRSGRAALRELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDT 153
+ ++ L+K LR+G +N ++++ + ++E + + + D
Sbjct: 224 LQTQVSLLKQRLRNG---------------PMNVDVLKPLPQLEPQAEVFTKEENPESDG 268
Query: 154 LATIIDILEYSNKKRLQQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLST 213
+ D + LQQ + ++ K + ++Q L ++ E QE+++
Sbjct: 269 EPVVEDGTSVKTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQ 328
Query: 214 YMDHEYSIKSVQISTLMRQLQQVKDSQQDELDDLGEMRRKVLESLSDKIQKKKKKI--LS 271
++ + + + L+ QL+ K+ + D G + + + + ++ K+++I L
Sbjct: 329 ELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLR 388
Query: 272 SVVAETQRPYEEALLQKMWESQDFLKCMQRFREFIDQFEENMPVLRAEVEE 322
S + + EE QK + + +++ + EE L+AE++E
Sbjct: 389 SRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDE 439
>gi|148277064 cut-like homeobox 1 isoform a [Homo sapiens]
Length = 1505
Score = 48.1 bits (113), Expect = 1e-05
Identities = 46/209 (22%), Positives = 91/209 (43%), Gaps = 9/209 (4%)
Query: 122 LSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRLQ----QLKSELQ 177
L + N+E E ++ E + + + + TL + + +++LQ + + +LQ
Sbjct: 122 LEEYNKEFAE-VKNQEVTIKALKEKIREYEQTLKNQAETIALEKEQKLQNDFAEKERKLQ 180
Query: 178 EWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQISTLMRQLQ--- 234
E + K+ E + + L +EKT+ E+ L T D E + K+ +I +M L+
Sbjct: 181 ETQMSTTSKLEEAEHKVQSLQTALEKTRTELFDLKTKYDEETTAKADEIEMIMTDLERAN 240
Query: 235 QVKDSQQDELDDLGEMRRKVLESLSDKIQ-KKKKKILSSVVAETQRPYEEALLQKMWESQ 293
Q + Q E + L E SL Q +K + ++ T+ E L K E
Sbjct: 241 QRAEVAQREAETLREQLSSANHSLQLASQIQKAPDVEQAIEVLTRSSLEVELAAKEREIA 300
Query: 294 DFLKCMQRFREFIDQFEENMPVLRAEVEE 322
++ +QR + + + EN +++E+
Sbjct: 301 QLVEDVQRLQASLTKLRENSASQISQLEQ 329
>gi|31652236 cut-like homeobox 1 isoform b [Homo sapiens]
Length = 678
Score = 48.1 bits (113), Expect = 1e-05
Identities = 46/209 (22%), Positives = 91/209 (43%), Gaps = 9/209 (4%)
Query: 122 LSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRLQ----QLKSELQ 177
L + N+E E ++ E + + + + TL + + +++LQ + + +LQ
Sbjct: 133 LEEYNKEFAE-VKNQEVTIKALKEKIREYEQTLKNQAETIALEKEQKLQNDFAEKERKLQ 191
Query: 178 EWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQISTLMRQLQ--- 234
E + K+ E + + L +EKT+ E+ L T D E + K+ +I +M L+
Sbjct: 192 ETQMSTTSKLEEAEHKVQSLQTALEKTRTELFDLKTKYDEETTAKADEIEMIMTDLERAN 251
Query: 235 QVKDSQQDELDDLGEMRRKVLESLSDKIQ-KKKKKILSSVVAETQRPYEEALLQKMWESQ 293
Q + Q E + L E SL Q +K + ++ T+ E L K E
Sbjct: 252 QRAEVAQREAETLREQLSSANHSLQLASQIQKAPDVEQAIEVLTRSSLEVELAAKEREIA 311
Query: 294 DFLKCMQRFREFIDQFEENMPVLRAEVEE 322
++ +QR + + + EN +++E+
Sbjct: 312 QLVEDVQRLQASLTKLRENSASQISQLEQ 340
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 48.1 bits (113), Expect = 1e-05
Identities = 70/271 (25%), Positives = 125/271 (46%), Gaps = 34/271 (12%)
Query: 94 MHAKIWLMKTSLRSGRAALRELRSRENFLSKLNRELIETIQEMENSTTLH-----VRALL 148
+ A++ +K L + E++++ + R+L E I + ENS TL V L
Sbjct: 505 LEAELKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVADLE 564
Query: 149 QQQDTLATIIDILEYSNKKRLQQLKSELQEWEEKKKCKMSYLE-QQAEQLNAKIEKT--- 204
+Q+D ++ E+ ++QL +L + E++ K +S LE ++ E K EKT
Sbjct: 565 KQRDCSQDLLKKREH----HIEQLNDKLSKTEKESKALLSALELKKKEYEELKEEKTLFS 620
Query: 205 --QEEVNFLSTYMDHEYSIKSVQISTLMRQL--QQVKDSQQDELDDLGEMRRKVLESLSD 260
+ E L T M+ E +I+ L L QQ+K + +E EM R E+LS
Sbjct: 621 CWKSENEKLLTQMESEKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDR---ENLSV 677
Query: 261 KIQKKKKKILS-SVVAETQR-PYEEALLQKMWESQDFLKCMQRFREFIDQFEENMPVLRA 318
+I+ + S SV ETQ+ Y E LQ+ E D Q+ ++ I+ L
Sbjct: 678 EIRNLHNVLDSKSVEVETQKLAYME--LQQKAEFSD-----QKHQKEIENMCLKTSQLTG 730
Query: 319 EVEELQAQTREPREVIFEDVLLRRPKCTPDM 349
+VE+L+ + + + + ++ + +C D+
Sbjct: 731 QVEDLEHKLQ-----LLSNEIMDKDRCYQDL 756
Score = 37.4 bits (85), Expect = 0.021
Identities = 53/271 (19%), Positives = 108/271 (39%), Gaps = 81/271 (29%)
Query: 114 ELRSRENFLSKLNRELIET----IQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRL 169
EL ++ L++E I+ QE++ + +H L + D L ++
Sbjct: 399 ELSRQQRSFQTLDQECIQMKARLTQELQQAKNMH-NVLQAELDKLTSV-----------K 446
Query: 170 QQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEV----NFLSTYMD--------- 216
QQL++ L+E+++K C+ Q ++ ++ ++ EE+ N L ++ +
Sbjct: 447 QQLENNLEEFKQKL-CRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHL 505
Query: 217 ------------------HEYSIKSVQISTLMRQLQQVKDSQQDEL-------------- 244
E K+ T++R LQ+ + Q++ L
Sbjct: 506 EAELKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVADLEK 565
Query: 245 -----DDLGEMRRKVLESLSDKIQK--KKKKILSSVVAETQRPYEEALLQK----MWESQ 293
DL + R +E L+DK+ K K+ K L S + ++ YEE +K W+S+
Sbjct: 566 QRDCSQDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEYEELKEEKTLFSCWKSE 625
Query: 294 DFLKCMQRFREFIDQFEENMPVLRAEVEELQ 324
+ + + Q E L++++ L+
Sbjct: 626 N--------EKLLTQMESEKENLQSKINHLE 648
Score = 37.4 bits (85), Expect = 0.021
Identities = 58/319 (18%), Positives = 129/319 (40%), Gaps = 40/319 (12%)
Query: 29 QQSKQETKPSTLPPVQQANSLHTSKMKTLTRVQPVFHFKPTTVVTSCQPKNPRELHR--- 85
Q+ + T+ S PP+++ + L S K R++ + + + ++ +L +
Sbjct: 2279 QEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRV 2338
Query: 86 ---RRKLDPGKMHAKIWLMKTSLRSGRAAL--RELRSRENFLSKLNRELIETIQEMENST 140
R+L+ + + + ++ G ++ L L +++ E EN T
Sbjct: 2339 ENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLT 2398
Query: 141 TLHVRALLQQQDTLATIIDILEYSNKKRLQQLKSELQEWEEKKKCKMSYLEQQAEQLN-- 198
LQ++ + ++I+ S + LQ+ + E + +EK M L+ Q ++LN
Sbjct: 2399 NE-----LQKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNER 2453
Query: 199 -AKIEKTQEEVNFLSTYMDHEYSIKSVQISTLMRQLQQVKDSQ---QDELDDLGEMRRKV 254
A + QE + + ++ + L++ L + K++ Q ++ L
Sbjct: 2454 VAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGL------- 2506
Query: 255 LESLSDKIQKKKKKILSSVVAETQRPYEEALLQK---------MWESQDFLKCMQRFREF 305
++ + D QK +KK + Q +E L+ K +W+ Q+ R
Sbjct: 2507 IQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNL-----ELRNL 2561
Query: 306 IDQFEENMPVLRAEVEELQ 324
+ E+ + VL+++ LQ
Sbjct: 2562 TVELEQKIQVLQSKNASLQ 2580
Score = 34.7 bits (78), Expect = 0.14
Identities = 31/168 (18%), Positives = 71/168 (42%), Gaps = 22/168 (13%)
Query: 114 ELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRLQQLK 173
EL +E L+K EL+ T + + ++T + LE KK + L
Sbjct: 328 ELIEKEKVLNKCRDELVRTTAQYDQASTKYTA---------------LEQKLKKLTEDLS 372
Query: 174 SELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQISTLMRQL 233
+ Q E + ++++ ++ ++ + Q L D E +++ ++Q
Sbjct: 373 CQRQNAESARCSLEQKIKEKEKEFQEELSRQQRSFQTL----DQECIQMKARLTQELQQA 428
Query: 234 QQVKDSQQDELDDLGEMRRKV---LESLSDKIQKKKKKILSSVVAETQ 278
+ + + Q ELD L +++++ LE K+ + ++ +S + E +
Sbjct: 429 KNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENE 476
Score = 31.6 bits (70), Expect = 1.2
Identities = 54/273 (19%), Positives = 115/273 (42%), Gaps = 24/273 (8%)
Query: 30 QSKQETKPSTLPPVQQANSLHTSKMKTLTRVQPVFHFKPTTVVTSCQPKNPRELHRRRKL 89
+ E P +L P+ ++NS + TL+ + HF + LH +
Sbjct: 1371 EQPNEQHPVSLAPLDESNSY---EHLTLSDKEVQMHFAELQEKFLSLQSEHKILHDQHCQ 1427
Query: 90 DPGKMH----------AKIWLMKTSLRSGRAAL---RELRSRENFLSKLNRELIETIQEM 136
KM A+ ++ T+LR+ + L +L E + L+ + +
Sbjct: 1428 MSSKMSELQTYVDSLKAENLVLSTNLRNFQGDLVKEMQLGLEEGLVPSLSSSCVPDSSSL 1487
Query: 137 EN-STTLHVRALLQQQDTLATIIDI--LEYSNKKRLQQLK-SELQEWEEKKKCKMSYLEQ 192
+ + RALL+Q ++ + ++ +N+ + ++ S LQE +K S +
Sbjct: 1488 SSLGDSSFYRALLEQTGDMSLLSNLEGAVSANQCSVDEVFCSSLQEENLTRKETPSAPAK 1547
Query: 193 QAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQISTLMRQLQQVKDSQQDELDDLGEMRR 252
E+L + E ++ + L M+ + +K+ +I ++L+Q+ S++ ELD L +
Sbjct: 1548 GVEELESLCEVYRQSLEKLEEKMESQGIMKNKEI----QELEQLLSSERQELDCLRKQYL 1603
Query: 253 KVLESLSDKIQKKKKKILSSVVAETQRPYEEAL 285
E K+ ++ S + AE ++ + +L
Sbjct: 1604 SENEQWQQKLTSVTLEMESKLAAEKKQTEQLSL 1636
Score = 29.3 bits (64), Expect = 5.8
Identities = 20/69 (28%), Positives = 36/69 (52%), Gaps = 2/69 (2%)
Query: 231 RQLQQVKD--SQQDELDDLGEMRRKVLESLSDKIQKKKKKILSSVVAETQRPYEEALLQK 288
R LQ++++ Q D+L + R+ L+SL +QK+K+K+ + T E L +
Sbjct: 15 RALQKIQELEGQLDKLKKEKQQRQFQLDSLEAALQKQKQKVENEKTEGTNLKRENQRLME 74
Query: 289 MWESQDFLK 297
+ ES + K
Sbjct: 75 ICESLEKTK 83
Score = 28.9 bits (63), Expect = 7.5
Identities = 37/175 (21%), Positives = 73/175 (41%), Gaps = 35/175 (20%)
Query: 170 QQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQISTL 229
Q L+SE+ + + K + L+Q+ L + K Q+EVN L ++ Q+ +
Sbjct: 1108 QALRSEMTDNQNNSKSEAGGLKQEIMTLKEEQNKMQKEVNDLLQ--------ENEQLMKV 1159
Query: 230 MRQLQQVKDSQQDELDDLGEMRRKVLESLSDKIQKKKKKILSSVVAE-------TQRPYE 282
M+ + ++ + + + R V E S++ Q K + V E Q
Sbjct: 1160 MKTKHECQNLESEPI------RNSVKERESERNQCNFKPQMDLEVKEISLDSYNAQLVQL 1213
Query: 283 EALLQ----KMWESQDFLKCMQRFREFIDQFEENMPVLRAEVEELQAQTREPREV 333
EA+L+ K+ ES+ +C+Q + +R ++E Q + +E+
Sbjct: 1214 EAMLRNKELKLQESEKEKECLQ----------HELQTIRGDLETSNLQDMQSQEI 1258
Score = 28.5 bits (62), Expect = 9.8
Identities = 36/150 (24%), Positives = 72/150 (48%), Gaps = 12/150 (8%)
Query: 190 LEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQI--STLMRQLQQVKDSQQDELDDL 247
LE Q +Q+N+ ++K EE+ + ++ E +K+ Q+ S + Q++ Q+D
Sbjct: 839 LESQ-KQMNSDLQKQCEELVQIKGEIE-ENLMKAEQMHQSFVAETSQRISKLQEDT---- 892
Query: 248 GEMRRKVLESLSDKIQKKKKKILSSVVAETQRPYEEALLQKMWESQDFLKCMQRFREFID 307
+ V E+LS K+K+ L + ET++ + L + +D LK +Q E +
Sbjct: 893 SAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLS 952
Query: 308 QFEENMPVL----RAEVEELQAQTREPREV 333
++ M + + E+EEL + +E+
Sbjct: 953 LEKKEMSSIISLNKREIEELTQENGTLKEI 982
>gi|50083279 centrosome protein 4 [Homo sapiens]
Length = 1140
Score = 47.4 bits (111), Expect = 2e-05
Identities = 47/209 (22%), Positives = 93/209 (44%), Gaps = 7/209 (3%)
Query: 116 RSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRLQQLKSE 175
++ E ++ LN + ++ +Q+ +R L++ ++T+ + + L N+K Q+L
Sbjct: 264 KTNEKLIAHLNIQ-VDFLQQANKDLEKRIRELMETKETVTSEVVNLSNKNEKLCQELTEI 322
Query: 176 LQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQISTLMRQLQQ 235
Q ++ ++ K LE ++L E +E LS D E ++ +Q+ + Q+
Sbjct: 323 DQLAQQLERHKEEVLETADKELG---EAKKEIKRKLSEMQDLEETMAKLQLE--LNLCQK 377
Query: 236 VKDSQQDELDDLGEMRRKVLESLSDKIQKKKKKILSSVVAETQRPYEEALLQKMWESQDF 295
K+ DEL ++ V+ L + Q+ KK+ S V E Q E ++ +
Sbjct: 378 EKERLSDELLVKSDL-ETVVHQLEQEKQRLSKKVESFAVTERQLTLEVERMRLEHGIKRR 436
Query: 296 LKCMQRFREFIDQFEENMPVLRAEVEELQ 324
+ R F+ EE + E+E LQ
Sbjct: 437 DRSPSRLDTFLKGIEEERDYYKKELERLQ 465
Score = 37.7 bits (86), Expect = 0.016
Identities = 34/179 (18%), Positives = 88/179 (49%), Gaps = 9/179 (5%)
Query: 157 IIDILEYSNKKRLQQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMD 216
I D+L+ ++ R+Q+L+ E+ + +E K++ +E + +IE + E+ LS +D
Sbjct: 195 IADLLQVADN-RIQELQQEVHQLQE----KLAMMESGVRDYSKQIELREREIERLSVALD 249
Query: 217 HEYSIKSVQISTLMRQLQQVKDSQQDELDDLGEMRRKVLESLSDKIQKKKKKILSSVVAE 276
S + + + + +++ ++D L + K LE ++ + K+ + S VV
Sbjct: 250 GGRSPDVLSLESRNKTNEKLIAHLNIQVDFL-QQANKDLEKRIRELMETKETVTSEVVNL 308
Query: 277 TQRPYEEALLQKMWESQDFLKCMQRFR-EFIDQFEENMPVLRAEVEELQAQTREPREVI 334
+ + E L Q++ E + ++R + E ++ ++ + + E++ ++ ++ E +
Sbjct: 309 SNK--NEKLCQELTEIDQLAQQLERHKEEVLETADKELGEAKKEIKRKLSEMQDLEETM 365
Score = 35.8 bits (81), Expect = 0.062
Identities = 39/216 (18%), Positives = 92/216 (42%), Gaps = 20/216 (9%)
Query: 127 RELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRLQQLKSELQEWEEKKKCK 186
+ ++E ++ +V+ L ++D L+ +L ++ L L+ E +
Sbjct: 509 QRMLERFEKYMEDIQSNVKLLTAERDKLS----VLYNEAQEELSALRKESTQTTAPHNI- 563
Query: 187 MSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQISTLMRQLQQVK------DSQ 240
+S +E++ E + + + E L ++H + S L + ++ + +S+
Sbjct: 564 VSLMEKEKELALSDLRRIMAEKEALREKLEHIEEVSLFGKSELEKTIEHLTCVNHQLESE 623
Query: 241 QDELDDLGEMRRKVLESLSDKIQKKKKKILSSVVAETQRPYEEALLQKMWESQDFLKCMQ 300
+ EL + ++ +ESL +K++ + +K S V ++ E ++ Q
Sbjct: 624 KYELKSKVLIMKETIESLENKLKVQAQKF-SHVAGDSSHQKTEVNSLRIVNEQ------- 675
Query: 301 RFREFIDQFEENMPVLRAEVEELQAQTREPREVIFE 336
+ +D ++ + + R E+E QAQ + E I E
Sbjct: 676 -LQRSVDDYQHRLSIKRGELESAQAQIKILEEKIDE 710
Score = 33.1 bits (74), Expect = 0.40
Identities = 44/224 (19%), Positives = 92/224 (41%), Gaps = 37/224 (16%)
Query: 131 ETIQEMENSTTL------HVRALLQQQDTLATIIDILEYSNKKRLQQLKSELQEWE---E 181
ETI+ +EN + HV Q T + I+ ++ + + L E
Sbjct: 636 ETIESLENKLKVQAQKFSHVAGDSSHQKTEVNSLRIVNEQLQRSVDDYQHRLSIKRGELE 695
Query: 182 KKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQISTLMRQLQQVKDSQQ 241
+ ++ LE++ ++LN K+ EE + + K++ + + + KD Q
Sbjct: 696 SAQAQIKILEEKIDELNLKMTSQDEEAHVMK---------KTIGV------IDKEKDFLQ 740
Query: 242 DELDDLGEMRRKVLESLSDKIQK-KKKKILSSVVAETQRPYEEALLQKMWESQDFLKCMQ 300
+ +D+ E + E+L++K + + KI+ S + +E L+ + E + +
Sbjct: 741 ETVDEKTEKIANLQENLANKEKAVAQMKIMISECESSVNQLKETLVNRDREINSLRRQLD 800
Query: 301 RFREFIDQ--------FEENMPVLRAEVEELQAQTREPREVIFE 336
+ +D+ F+EN R ++L RE +E+ E
Sbjct: 801 AAHKELDEVGRSREIAFKEN----RRLQDDLATMARENQEISLE 840
>gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens]
Length = 898
Score = 47.4 bits (111), Expect = 2e-05
Identities = 59/252 (23%), Positives = 111/252 (44%), Gaps = 21/252 (8%)
Query: 78 KNPRELHRRRKLDPGKMH-AKIWLMKTSLRSGRAALRELRSRENFLSKLNRELIETIQEM 136
K E + K D +MH AKI ++ R+ + + ELR+ + L E + T E+
Sbjct: 460 KGELEKQMQEKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTKVKCLEDERLRTEDEL 519
Query: 137 E------NSTTLHVRALLQQQDTLATIIDILEYSNKKRLQQLKSE----------LQEWE 180
N ++ LL + T + + L+ K+ ++ LK E LQ+
Sbjct: 520 SKYKEIINRQKAEIQNLLDKVKTADQLQEQLQ-RGKQEIENLKEEVESLNSLINDLQKDI 578
Query: 181 EKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQISTLMRQLQQVKDSQ 240
E + + S L E+L +K + Q E N L + D + S Q+ + Q++Q +
Sbjct: 579 EGSRKRESELLLFTERLTSKNAQLQSESNSLQSQFD-KVSCSESQLQSQCEQMKQTNINL 637
Query: 241 QDELDDLGEMRRKVLESLSDKI--QKKKKKILSSVVAETQRPYEEALLQKMWESQDFLKC 298
+ L E+R++ +++L ++ ++ + K LS+ V E + + +D K
Sbjct: 638 ESRLLKEEELRKEEVQTLQAELACRQTEVKALSTQVEELKDELVTQRRKHASSIKDLTKQ 697
Query: 299 MQRFREFIDQFE 310
+Q+ R +DQ E
Sbjct: 698 LQQARRKLDQVE 709
Score = 45.1 bits (105), Expect = 1e-04
Identities = 46/259 (17%), Positives = 120/259 (46%), Gaps = 28/259 (10%)
Query: 109 RAALRELRSRENFLSKLNRE---LIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSN 165
R A +EL N + +L++E L + + E TT +R + + ++ + + + ++++
Sbjct: 337 RDANKELEKNTNKIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINSHVIKVKWAQ 396
Query: 166 KKRLQQLKSELQEWEEKKKC--KMSYLEQQAEQLNAK----IEKTQEEVNFLSTYMDHEY 219
K ++ S + ++ K+ K++ +++A+Q+ I+ QE S +D +
Sbjct: 397 NKLKAEMDSHKETKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKL 456
Query: 220 SIKSVQISTLM--------------RQLQQVKDSQQDELDDLGEMRRKVLESLSDKIQKK 265
+ ++ M ++L+ +K + ++ +D+L +R KV ++++ +
Sbjct: 457 RVTKGELEKQMQEKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTKVKCLEDERLRTE 516
Query: 266 KKKILSSVVAETQRPYEEALLQKMWESQDFLKCMQRFREFIDQFEENMPVLRAEVEELQ- 324
+ + Q+ + LL K+ + + +QR ++ I+ +E + L + + +LQ
Sbjct: 517 DELSKYKEIINRQKAEIQNLLDKVKTADQLQEQLQRGKQEIENLKEEVESLNSLINDLQK 576
Query: 325 ----AQTREPREVIFEDVL 339
++ RE ++F + L
Sbjct: 577 DIEGSRKRESELLLFTERL 595
>gi|31652238 cut-like homeobox 1 isoform c [Homo sapiens]
Length = 676
Score = 47.0 bits (110), Expect = 3e-05
Identities = 47/208 (22%), Positives = 91/208 (43%), Gaps = 9/208 (4%)
Query: 122 LSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRLQ----QLKSELQ 177
L + N+E E ++ E + + + + TL + + +++LQ + + +LQ
Sbjct: 133 LEEYNKEFAE-VKNQEVTIKALKEKIREYEQTLKNQAETIALEKEQKLQNDFAEKERKLQ 191
Query: 178 EWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQISTLMRQLQ--- 234
E + K+ E + + L +EKT+ E+ L T D E + K+ +I +M L+
Sbjct: 192 ETQMSTTSKLEEAEHKVQSLQTALEKTRTELFDLKTKYDEETTAKADEIEMIMTDLERAN 251
Query: 235 QVKDSQQDELDDLGEMRRKVLESLSDKIQKKKKKILSSVVAETQRPYEEALLQKMWESQD 294
Q + Q E + L E SL Q +K ++ V T+ E L K E
Sbjct: 252 QRAEVAQREAETLREQLSSANHSLQLASQIQKAPDVAIEVL-TRSSLEVELAAKEREIAQ 310
Query: 295 FLKCMQRFREFIDQFEENMPVLRAEVEE 322
++ +QR + + + EN +++E+
Sbjct: 311 LVEDVQRLQASLTKLRENSASQISQLEQ 338
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 47.0 bits (110), Expect = 3e-05
Identities = 72/308 (23%), Positives = 129/308 (41%), Gaps = 52/308 (16%)
Query: 78 KNPRELHRRRKLDPGKMHAKIWLMKTSLRSGRAALRELRSRENFLSK------------- 124
KN E H++ + + +H ++ K LR+ + + L + N L+
Sbjct: 585 KNQSESHKQAQEN---LHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLD 641
Query: 125 ----------LNRELIETIQ--EMENSTTLHVRALLQQQDTLATIIDILEYSNKK----- 167
L+ E +T Q +++N AL +Q L I L+ K
Sbjct: 642 IQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQDKQ 701
Query: 168 -RLQQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQI 226
QL+S L+E++EK LEQ+ E+L +I+K E + L E +++ +Q
Sbjct: 702 EHCSQLESHLKEYKEKYLS----LEQKTEELEGQIKKL--EADSLEVKASKEQALQDLQ- 754
Query: 227 STLMRQLQQVKDSQQDELDDLGEMRRKVLESLSDKIQKKKKKILSSVVAETQRPYEEALL 286
RQL + + EL EM ++++ S +QKK + + S T++ E+ +L
Sbjct: 755 --QQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQIL 812
Query: 287 QKMWESQDFLKCMQRFREFIDQFEENMPVLRAEVEELQAQTREPREVIFEDVLLRRPKCT 346
+ QDF Q E Q EE ++ V ELQ + + +E + ++ + K +
Sbjct: 813 K-----QDFETLSQ---ETKIQHEELNNRIQTTVTELQ-KVKMEKEALMTELSTVKDKLS 863
Query: 347 PDMDVILN 354
D + N
Sbjct: 864 KVSDSLKN 871
Score = 40.0 bits (92), Expect = 0.003
Identities = 64/264 (24%), Positives = 110/264 (41%), Gaps = 50/264 (18%)
Query: 112 LRELRSRENFLSKLNRELIETIQEMENSTTL-------------HVRALLQQQDTLATII 158
L++L+S N L++ N+ L E + + E T +++A L Q+D +
Sbjct: 290 LQKLKSSVNELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQL 349
Query: 159 DI-------------LEYSNK-KRLQQLKSELQEWEEKK---KCKMSYLEQQAEQLNAKI 201
+E S K + Q+LK EL E E K K + L+QQ E+
Sbjct: 350 QSRLSASETSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHG 409
Query: 202 EKTQEEVNFL-STYMDHEYSI----------KSVQISTLMRQLQQVKDSQQDELDDLGE- 249
+ Q E+N L S ++ E + + + LM + QQV D Q +L L E
Sbjct: 410 LQLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQL-KLSRLEEQ 468
Query: 250 MRRKVLESL-------SDKIQKKKKKILSSVVAETQRPYEEALLQKMWESQDFLKCMQRF 302
++ KV S K Q ++++ L R + L Q + + D + +Q
Sbjct: 469 LKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNL 528
Query: 303 REFIDQFEENMPVLRAEVEELQAQ 326
+ + +EN+ +L E E+L A+
Sbjct: 529 EALLQKSKENISLLEKEREDLYAK 552
Score = 35.8 bits (81), Expect = 0.062
Identities = 42/236 (17%), Positives = 101/236 (42%), Gaps = 10/236 (4%)
Query: 93 KMHAKIWLMKTSLRSGRAALRELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQD 152
+++ + L T L +E+ S + E +E+I++ + L Q +
Sbjct: 758 QLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFE 817
Query: 153 TLATIIDILEYSNKKRLQQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLS 212
TL+ I R+Q +ELQ+ + +K+ M+ L + K+ K + +
Sbjct: 818 TLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTEL----STVKDKLSKVSDSLKNSK 873
Query: 213 TYMDHEYSIKSVQISTLMRQLQQVKDSQQDELDDLGEMRRKVLESLSDKIQKKKKKILSS 272
+ + E I L + +++K Q ++++ + ++++ +SL +K+K S
Sbjct: 874 SEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSL------EKEKEASH 927
Query: 273 VVAETQRPYEEALLQKMWESQDFLKCMQRFREFIDQFEENMPVLRAEVEELQAQTR 328
+ +E L+Q + K Q+ + I++ +++ + ++E LQ + +
Sbjct: 928 QLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQGELK 983
Score = 34.7 bits (78), Expect = 0.14
Identities = 49/228 (21%), Positives = 100/228 (43%), Gaps = 28/228 (12%)
Query: 114 ELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDILEYSNKKRLQQLK 173
EL + L EL++ +E+ L + L+Q Q T++D + ++ ++LK
Sbjct: 199 ELNKEATVIQDLKTELLQR-PGIEDVAVLK-KELVQVQ----TLMDNMTLERERESEKLK 252
Query: 174 SELQEWEEKKKCKMSYLEQQA--EQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQISTLMR 231
E KK + Y +A QL +++ K +EV + Y+ +KS ++ L +
Sbjct: 253 DEC------KKLQSQYASSEATISQLRSELAKGPQEV---AVYVQELQKLKS-SVNELTQ 302
Query: 232 QLQQVKDSQQDELDDLGEMRRKVLESLSDKIQKKK------KKILSSVVAETQRPYEEAL 285
+ Q + ++ + D ++ K E + + KK +K L +++ E
Sbjct: 303 KNQTLTENLLKKEQDYTKLEEKHNE---ESVSKKNIQATLHQKDLDCQQLQSRLSASETS 359
Query: 286 LQKMW-ESQDFLKCMQRFREFIDQFEENMPVLRAEVEELQAQTREPRE 332
L ++ E + + Q+ +E + + E L+AE ++LQ Q E +
Sbjct: 360 LHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQ 407
Score = 34.3 bits (77), Expect = 0.18
Identities = 53/255 (20%), Positives = 109/255 (42%), Gaps = 32/255 (12%)
Query: 101 MKTSLRSGRAALRELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDI 160
M+ +L+ + + L + +L EL ++QE L+Q Q+TL
Sbjct: 905 MENTLKEQKELKKSLEKEKEASHQLKLEL-NSMQEQ----------LIQAQNTLK----- 948
Query: 161 LEYSNKKRLQQLKSELQEWEEKKKCKMSYLEQ-QAEQLNAKIEKTQEEVNFLS--TYMDH 217
N+K QQL+ + E ++ + K +E Q E A ++KT+ E T
Sbjct: 949 ---QNEKEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQ 1005
Query: 218 EYSIKSVQISTLMRQLQQVKDS-QQDELDDLGE-----MRRKVLESLSDKIQKKKKKILS 271
E + + +IS L ++ +++ +Q + D G R+ L+S+ +K+ ++ ++S
Sbjct: 1006 ELAAEKEKISVLQNNYEKSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLIS 1065
Query: 272 --SVVAETQRPYEEALLQKMWESQDFLKCMQRFREFIDQFEENMPVLRAEVEELQAQTRE 329
+ + + +E K QD K Q+ +E ++ + +EL + +
Sbjct: 1066 NRNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSK 1125
Query: 330 PREVIFEDVLLRRPK 344
E+ E++ R+ K
Sbjct: 1126 LAEI--EEIKCRQEK 1138
>gi|237858621 polyamine modulated factor 1 binding protein 1 isoform
b [Homo sapiens]
Length = 882
Score = 46.6 bits (109), Expect = 3e-05
Identities = 72/357 (20%), Positives = 138/357 (38%), Gaps = 43/357 (12%)
Query: 6 QKPKHSGTHSIVQEFQVPDYVPWQQSKQETKPSTLPPVQQ--------------ANSLHT 51
Q+P++ G HS V+ + P + Q Q+ V Q +N+L
Sbjct: 67 QEPENKGDHSKVRIYTSPCMIQEHQETQKRLSEVWQKVSQQDDLIQELRNKLACSNALVL 126
Query: 52 SKMKTLTRVQPVF------HFKPTTVVTSCQPKNPRELHRRRKLDPGKMHAKIWL----- 100
+ K L ++Q F H P + C+ H + + D +H + +
Sbjct: 127 EREKALIKLQADFASCTATHRYPPSSSEECEDIKKILKHLQEQKDSQCLHVEEYQNLVKD 186
Query: 101 ----MKTSLRSGRAALRELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLAT 156
++ R ++++ E L L E I+ + T+ ++ LQ+ T
Sbjct: 187 LRVELEAVSEQKRNIMKDMMKLELDLHGLREETSAHIERKDKDITI-LQCRLQELQLEFT 245
Query: 157 IIDILEYSNKKRLQQLKSELQEWEEK-KKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYM 215
L K LQ+ LQE E+K + + S L+++ E + T+ E+
Sbjct: 246 ETQKLTLKKDKFLQEKDEMLQELEKKLTQVQNSLLKKEKELEKQQCMATELEMTVKEAKQ 305
Query: 216 DHEYSIKSVQISTLMRQLQQVKDSQQDELDDLGEMRRKVLESLSDKIQKKKKKILSSVVA 275
D K + L ++Q++K+S L++ + R + + K++ + +
Sbjct: 306 DKS---KEAECKALQAEVQKLKNS----LEEAKQQERLAAQQAAQ--CKEEAALAGCHLE 356
Query: 276 ETQRPYEEALL---QKMWESQDFLKCMQRFREFIDQFEENMPVLRAEVEELQAQTRE 329
+TQR ++ LL QK Q+ + +Q ++ E+ R VEEL + E
Sbjct: 357 DTQRKLQKGLLLDKQKADTIQELQRELQMLQKESSMAEKEQTSNRKRVEELSLELSE 413
>gi|237858619 polyamine modulated factor 1 binding protein 1 isoform
a [Homo sapiens]
Length = 1007
Score = 46.6 bits (109), Expect = 3e-05
Identities = 72/357 (20%), Positives = 138/357 (38%), Gaps = 43/357 (12%)
Query: 6 QKPKHSGTHSIVQEFQVPDYVPWQQSKQETKPSTLPPVQQ--------------ANSLHT 51
Q+P++ G HS V+ + P + Q Q+ V Q +N+L
Sbjct: 212 QEPENKGDHSKVRIYTSPCMIQEHQETQKRLSEVWQKVSQQDDLIQELRNKLACSNALVL 271
Query: 52 SKMKTLTRVQPVF------HFKPTTVVTSCQPKNPRELHRRRKLDPGKMHAKIWL----- 100
+ K L ++Q F H P + C+ H + + D +H + +
Sbjct: 272 EREKALIKLQADFASCTATHRYPPSSSEECEDIKKILKHLQEQKDSQCLHVEEYQNLVKD 331
Query: 101 ----MKTSLRSGRAALRELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLAT 156
++ R ++++ E L L E I+ + T+ ++ LQ+ T
Sbjct: 332 LRVELEAVSEQKRNIMKDMMKLELDLHGLREETSAHIERKDKDITI-LQCRLQELQLEFT 390
Query: 157 IIDILEYSNKKRLQQLKSELQEWEEK-KKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYM 215
L K LQ+ LQE E+K + + S L+++ E + T+ E+
Sbjct: 391 ETQKLTLKKDKFLQEKDEMLQELEKKLTQVQNSLLKKEKELEKQQCMATELEMTVKEAKQ 450
Query: 216 DHEYSIKSVQISTLMRQLQQVKDSQQDELDDLGEMRRKVLESLSDKIQKKKKKILSSVVA 275
D K + L ++Q++K+S L++ + R + + K++ + +
Sbjct: 451 DKS---KEAECKALQAEVQKLKNS----LEEAKQQERLAAQQAAQ--CKEEAALAGCHLE 501
Query: 276 ETQRPYEEALL---QKMWESQDFLKCMQRFREFIDQFEENMPVLRAEVEELQAQTRE 329
+TQR ++ LL QK Q+ + +Q ++ E+ R VEEL + E
Sbjct: 502 DTQRKLQKGLLLDKQKADTIQELQRELQMLQKESSMAEKEQTSNRKRVEELSLELSE 558
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.129 0.360
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,262,942
Number of Sequences: 37866
Number of extensions: 569816
Number of successful extensions: 5769
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 111
Number of HSP's successfully gapped in prelim test: 734
Number of HSP's that attempted gapping in prelim test: 3887
Number of HSP's gapped (non-prelim): 2055
length of query: 363
length of database: 18,247,518
effective HSP length: 104
effective length of query: 259
effective length of database: 14,309,454
effective search space: 3706148586
effective search space used: 3706148586
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.