Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 238859651
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|238859651 pleckstrin homology domain containing family A
member 4 isoform 1 [Homo sapiens]
(779 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|238859651 pleckstrin homology domain containing family A memb... 1607 0.0
gi|238859653 pleckstrin homology domain containing family A memb... 1132 0.0
gi|239047795 pleckstrin homology domain containing, family A mem... 176 6e-44
gi|219689123 pleckstrin homology domain containing, family A mem... 143 5e-34
gi|19923493 pleckstrin homology domain containing, family A memb... 143 5e-34
gi|37595548 phosphoinositol 3-phosphate-binding protein-3 [Homo ... 143 5e-34
gi|188497618 connector enhancer of kinase suppressor of Ras 1 [H... 67 8e-11
gi|24432056 hypothetical protein LOC144717 [Homo sapiens] 65 2e-10
gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo sa... 64 7e-10
gi|194733753 phosphoinositide-binding protein PIP3-E isoform 1 [... 63 1e-09
gi|194733747 phosphoinositide-binding protein PIP3-E isoform 1 [... 63 1e-09
gi|40354212 phosphoinositide-binding protein PIP3-E isoform 2 [H... 63 1e-09
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 61 3e-09
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 60 6e-09
gi|18959210 WIRE protein [Homo sapiens] 60 1e-08
gi|34013590 Rho GTPase activating protein 2 [Homo sapiens] 59 2e-08
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 58 4e-08
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 58 4e-08
gi|19924099 synapsin I isoform Ia [Homo sapiens] 56 1e-07
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 55 2e-07
gi|237757326 synaptojanin 1 isoform d [Homo sapiens] 55 2e-07
gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 55 2e-07
gi|237757312 synaptojanin 1 isoform c [Homo sapiens] 55 3e-07
gi|41393057 connector enhancer of kinase suppressor of Ras 2 [Ho... 55 3e-07
gi|110832843 TBP-associated factor 4 [Homo sapiens] 54 4e-07
gi|54860079 nadrin isoform 1 [Homo sapiens] 54 4e-07
gi|210032580 SET domain containing 1B [Homo sapiens] 54 4e-07
gi|157785645 SPEG complex locus [Homo sapiens] 54 4e-07
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 54 4e-07
gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2 pre... 54 4e-07
>gi|238859651 pleckstrin homology domain containing family A member
4 isoform 1 [Homo sapiens]
Length = 779
Score = 1607 bits (4161), Expect = 0.0
Identities = 779/779 (100%), Positives = 779/779 (100%)
Query: 1 MEGSRPRSSLSLASSASTISSLSSLSPKKPTRAVNKIHAFGKRGNALRRDPNLPVHIRGW 60
MEGSRPRSSLSLASSASTISSLSSLSPKKPTRAVNKIHAFGKRGNALRRDPNLPVHIRGW
Sbjct: 1 MEGSRPRSSLSLASSASTISSLSSLSPKKPTRAVNKIHAFGKRGNALRRDPNLPVHIRGW 60
Query: 61 LHKQDSSGLRLWKRRWFVLSGHCLFYYKDSREESVLGSVLLPSYNIRPDGPGAPRGRRFT 120
LHKQDSSGLRLWKRRWFVLSGHCLFYYKDSREESVLGSVLLPSYNIRPDGPGAPRGRRFT
Sbjct: 61 LHKQDSSGLRLWKRRWFVLSGHCLFYYKDSREESVLGSVLLPSYNIRPDGPGAPRGRRFT 120
Query: 121 FTAEHPGMRTYVLAADTLEDLRGWLRALGRASRAEGDDYGQPRSPARPQPGEGPGGPGGP 180
FTAEHPGMRTYVLAADTLEDLRGWLRALGRASRAEGDDYGQPRSPARPQPGEGPGGPGGP
Sbjct: 121 FTAEHPGMRTYVLAADTLEDLRGWLRALGRASRAEGDDYGQPRSPARPQPGEGPGGPGGP 180
Query: 181 PEVSRGEEGRISESPEVTRLSRGRGRPRLLTPSPTTDLHSGLQMRRARSPDLFTPLSRPP 240
PEVSRGEEGRISESPEVTRLSRGRGRPRLLTPSPTTDLHSGLQMRRARSPDLFTPLSRPP
Sbjct: 181 PEVSRGEEGRISESPEVTRLSRGRGRPRLLTPSPTTDLHSGLQMRRARSPDLFTPLSRPP 240
Query: 241 SPLSLPRPRSAPARRPPAPSGDTAPPARPHTPLSRIDVRPPLDWGPQRQTLSRPPTPRRG 300
SPLSLPRPRSAPARRPPAPSGDTAPPARPHTPLSRIDVRPPLDWGPQRQTLSRPPTPRRG
Sbjct: 241 SPLSLPRPRSAPARRPPAPSGDTAPPARPHTPLSRIDVRPPLDWGPQRQTLSRPPTPRRG 300
Query: 301 PPSEAGGGKPPRSPQHWSQEPRTQAHSGSPTYLQLPPRPPGTRASMVLLPGPPLESTFHQ 360
PPSEAGGGKPPRSPQHWSQEPRTQAHSGSPTYLQLPPRPPGTRASMVLLPGPPLESTFHQ
Sbjct: 301 PPSEAGGGKPPRSPQHWSQEPRTQAHSGSPTYLQLPPRPPGTRASMVLLPGPPLESTFHQ 360
Query: 361 SLETDTLLTKLCGQDRLLRRLQEEIDQKQEEKEQLEAALELTRQQLGQATREAGAPGRAW 420
SLETDTLLTKLCGQDRLLRRLQEEIDQKQEEKEQLEAALELTRQQLGQATREAGAPGRAW
Sbjct: 361 SLETDTLLTKLCGQDRLLRRLQEEIDQKQEEKEQLEAALELTRQQLGQATREAGAPGRAW 420
Query: 421 GRQRLLQDRLVSVRATLCHLTQERERVWDTYSGLEQELGTLRETLEYLLHLGSPQDRVSA 480
GRQRLLQDRLVSVRATLCHLTQERERVWDTYSGLEQELGTLRETLEYLLHLGSPQDRVSA
Sbjct: 421 GRQRLLQDRLVSVRATLCHLTQERERVWDTYSGLEQELGTLRETLEYLLHLGSPQDRVSA 480
Query: 481 QQQLWMVEDTLAGLGGPQKPPPHTEPDSPSPVLQGEESSERESLPESLELSSPRSPETDW 540
QQQLWMVEDTLAGLGGPQKPPPHTEPDSPSPVLQGEESSERESLPESLELSSPRSPETDW
Sbjct: 481 QQQLWMVEDTLAGLGGPQKPPPHTEPDSPSPVLQGEESSERESLPESLELSSPRSPETDW 540
Query: 541 GRPPGGDKDLASPHLGLGSPRVSRASSPEGRHLPSPQLGTKAPVARPRMSAQEQLERMRR 600
GRPPGGDKDLASPHLGLGSPRVSRASSPEGRHLPSPQLGTKAPVARPRMSAQEQLERMRR
Sbjct: 541 GRPPGGDKDLASPHLGLGSPRVSRASSPEGRHLPSPQLGTKAPVARPRMSAQEQLERMRR 600
Query: 601 NQECGRPFPRPTSPRLLTLGRTLSPARRQPDVEQRPVVGHSGAQKWLRSSGSWSSPRNTT 660
NQECGRPFPRPTSPRLLTLGRTLSPARRQPDVEQRPVVGHSGAQKWLRSSGSWSSPRNTT
Sbjct: 601 NQECGRPFPRPTSPRLLTLGRTLSPARRQPDVEQRPVVGHSGAQKWLRSSGSWSSPRNTT 660
Query: 661 PYLPTSEGHRERVLSLSQALATEASQWHRMMTGGNLDSQGDPLPGVPLPPSDPTRQETPP 720
PYLPTSEGHRERVLSLSQALATEASQWHRMMTGGNLDSQGDPLPGVPLPPSDPTRQETPP
Sbjct: 661 PYLPTSEGHRERVLSLSQALATEASQWHRMMTGGNLDSQGDPLPGVPLPPSDPTRQETPP 720
Query: 721 PRSPPVANSGSTGFSRRGSGRGGGPTPWGPAWDAGIAPPVLPQDEGAWPLRVTLLQSSF 779
PRSPPVANSGSTGFSRRGSGRGGGPTPWGPAWDAGIAPPVLPQDEGAWPLRVTLLQSSF
Sbjct: 721 PRSPPVANSGSTGFSRRGSGRGGGPTPWGPAWDAGIAPPVLPQDEGAWPLRVTLLQSSF 779
>gi|238859653 pleckstrin homology domain containing family A member
4 isoform 2 [Homo sapiens]
Length = 583
Score = 1132 bits (2929), Expect = 0.0
Identities = 564/612 (92%), Positives = 567/612 (92%), Gaps = 32/612 (5%)
Query: 1 MEGSRPRSSLSLASSASTISSLSSLSPKKPTRAVNKIHAFGKRGNALRRDPNLPVHIRGW 60
MEGSRPRSSLSLASSASTISSLSSLSPKKPTRAVNKIHAFGKRGNALRRDPNLPVHIRGW
Sbjct: 1 MEGSRPRSSLSLASSASTISSLSSLSPKKPTRAVNKIHAFGKRGNALRRDPNLPVHIRGW 60
Query: 61 LHKQDSSGLRLWKRRWFVLSGHCLFYYKDSREESVLGSVLLPSYNIRPDGPGAPRGRRFT 120
LHKQDSSGLRLWKRRWFVLSGHCLFYYKDSREESVLGSVLLPSYNIRPDGPGAPRGRRFT
Sbjct: 61 LHKQDSSGLRLWKRRWFVLSGHCLFYYKDSREESVLGSVLLPSYNIRPDGPGAPRGRRFT 120
Query: 121 FTAEHPGMRTYVLAADTLEDLRGWLRALGRASRAEGDDYGQPRSPARPQPGEGPGGPGGP 180
FTAEHPGMRTYVLAADTLEDLRGWLRALGRASRAEGDDYGQPRSPARPQPGEGPGGPGGP
Sbjct: 121 FTAEHPGMRTYVLAADTLEDLRGWLRALGRASRAEGDDYGQPRSPARPQPGEGPGGPGGP 180
Query: 181 PEVSRGEEGRISESPEVTRLSRGRGRPRLLTPSPTTDLHSGLQMRRARSPDLFTPLSRPP 240
PEVSRGEEGRISESPEVTRLSRGRGRPRLLTPSPTTDLHSGLQMRRARSPDLFTPLSRPP
Sbjct: 181 PEVSRGEEGRISESPEVTRLSRGRGRPRLLTPSPTTDLHSGLQMRRARSPDLFTPLSRPP 240
Query: 241 SPLSLPRPRSAPARRPPAPSGDTAPPARPHTPLSRIDVRPPLDWGPQRQTLSRPPTPRRG 300
SPLSLPRPRSAPARRPPAPSGDTAPPARPHTPLSRIDVRPPLDWGPQRQTLSRPPTPRRG
Sbjct: 241 SPLSLPRPRSAPARRPPAPSGDTAPPARPHTPLSRIDVRPPLDWGPQRQTLSRPPTPRRG 300
Query: 301 PPSEAGGGKPPRSPQHWSQEPRTQAHSGSPTYLQLPPRPPGTRASMVLLPGPPLESTFHQ 360
PPSEAGGGKPPRSPQHWSQEPRTQ PGPPLESTFHQ
Sbjct: 301 PPSEAGGGKPPRSPQHWSQEPRTQ-------------------------PGPPLESTFHQ 335
Query: 361 SLETDTLLTKLCGQDRLLRRLQEEIDQKQEEKEQLEAALELTRQQLGQATREAGAPGRAW 420
SLETDTLLTKLCGQDRLLRRLQEEIDQKQEEKEQLEAALELTRQQLGQATREAGAPGRAW
Sbjct: 336 SLETDTLLTKLCGQDRLLRRLQEEIDQKQEEKEQLEAALELTRQQLGQATREAGAPGRAW 395
Query: 421 GRQRLLQDRLVSVRATLCHLTQERERVWDTYSGLEQELGTLRETLEYLLHLGSPQDRVSA 480
GRQRLLQDRLVSVRATLCHLTQERERVWDTYSGLEQELGTLRETLEYLLHLGSPQDRVSA
Sbjct: 396 GRQRLLQDRLVSVRATLCHLTQERERVWDTYSGLEQELGTLRETLEYLLHLGSPQDRVSA 455
Query: 481 QQQLWMVEDTLAGLGGPQKPPPHTEPDSPSPVLQGEESSERESLPESLELSSPRSPETDW 540
QQQLWMVEDTLAGLGGPQKPPPHTEPDSPSPVLQGEESSERESLPESLELSSPRSPETDW
Sbjct: 456 QQQLWMVEDTLAGLGGPQKPPPHTEPDSPSPVLQGEESSERESLPESLELSSPRSPETDW 515
Query: 541 GRPPGGDKDLASPHLGLGSPRVSRASSPEGRHLPSPQLGTKAPVARPRMSAQEQLERMRR 600
GRPPGGDKDLASPHLGLGSPRVSRASSPEGRHLPSPQLGTK+ P L RR
Sbjct: 516 GRPPGGDKDLASPHLGLGSPRVSRASSPEGRHLPSPQLGTKSKEHHP------LLADFRR 569
Query: 601 NQECG-RPFPRP 611
+ G +P P P
Sbjct: 570 SPGAGSQPLPSP 581
>gi|239047795 pleckstrin homology domain containing, family A member
7 [Homo sapiens]
Length = 1121
Score = 176 bits (447), Expect = 6e-44
Identities = 127/365 (34%), Positives = 174/365 (47%), Gaps = 38/365 (10%)
Query: 5 RPRSSLSLASSASTISSLSSLSPKKPTRAVNKIHAFGKRGNALRRDPNLPVHIRGWLHKQ 64
RP S +S S+A T S+L + K ++ +K+H+FGKR A+RR+PN+PV +RGWLHKQ
Sbjct: 115 RPSSMVSETSTAGTASTLEAKPGPKIIKSSSKVHSFGKRDQAIRRNPNVPVVVRGWLHKQ 174
Query: 65 DSSGLRLWKRRWFVLSGHCLFYYKDSREESVLGSVLLPSYNIRPDGPGAPRGRRFTFTAE 124
DSSG+RLWKRRWFVL+ +CLFYYKDSREE+VLGS+ LPSY I P P R+++F A
Sbjct: 175 DSSGMRLWKRRWFVLADYCLFYYKDSREEAVLGSIPLPSYVISPVAPEDRISRKYSFKAV 234
Query: 125 H-------------------PGMRTYVLAADTLEDLRGWLRALGRASRAEGDDYGQPRSP 165
H GMRTY +ADT ED+ W+RA+ +A++ +
Sbjct: 235 HTGMRALIYNSSTAGSQAEQSGMRTYYFSADTQEDMNAWVRAMNQAAQV----LSRSSLK 290
Query: 166 ARPQPGEGPGGPGGPPEVSRGEEGRISESPEVTRLSRGRGRPRLLTPSPTTDLHSGLQMR 225
+ E P S E GR+ P TR RG ++ + G Q R
Sbjct: 291 RDMEKVERQAVPQANHTESCHECGRV--GPGHTRDCPHRGHDDIV--NFERQEQEGEQYR 346
Query: 226 RARSP-DLFTPLSRPPSPLSLPRPRSAPARRPPAPSGDTAPPARPHTPLSRIDVRPPLDW 284
R P + S+ SP S + P P G A P R + + P +
Sbjct: 347 SQRDPLEGKRDRSKARSPYSPAEEDALFMDLPTGPRGQQAQPQR-----AEKNGMLPASY 401
Query: 285 GPQRQT----LSRPPTPRRGPPSEAGGGKPPRSPQHWSQEPRTQAHSGSPTYLQLPPRPP 340
GP Q R PR P + +HW++ + + S P LP + P
Sbjct: 402 GPGEQNGTGGYQRAFPPRTNPEKHSQRKSNLAQVEHWARAQKGDSRS-LPLDQTLPRQGP 460
Query: 341 GTRAS 345
G S
Sbjct: 461 GQSLS 465
Score = 120 bits (301), Expect = 5e-27
Identities = 117/411 (28%), Positives = 169/411 (41%), Gaps = 44/411 (10%)
Query: 162 PRSPARPQPGEGPGGPGGPPEVS-----------RGEEGRISESPEVTRLSRGRGRPRLL 210
P+S P G P P + EE R V +L + R +
Sbjct: 474 PKSTRHPSGGSSPPPRNLPSDYKYAQDRASHLKMSSEERRAHRDGTVWQLYEWQQRQQFR 533
Query: 211 TPSPTTDLHSGLQMRRARSPDLFTPLSRPPSPLSLPRPRS---APARRPPAPSGDTAPPA 267
SPT + G SP+ FT R S L +PR S +P+ PP PP
Sbjct: 534 HGSPTAPICLG-------SPE-FTDQGRSRSMLEVPRSISVPPSPSDIPPPGPPRVFPPR 585
Query: 268 RPHTPLSRIDVRPPLDWGPQRQTLSRPPTPRRGPPSEAGGGKPPRSPQ------HWSQEP 321
RPHTP R+ V+PP +L P RG + RS H P
Sbjct: 586 RPHTPAERVTVKPPDQRRSVDISLGDSPRRARGHAVKNSSHVDRRSMPSMGYMTHTVSAP 645
Query: 322 RTQAHSGSPTYLQLPPRPPGTRASMV---LLPGPPLESTFHQSLETDTLLTKLCGQDRLL 378
S TYLQL M LL L+ +TD L+ C QDR+L
Sbjct: 646 SLHGKSADDTYLQLKKDLEYLDLKMTGRDLLKDRSLKPVKIAESDTDVKLSIFCEQDRVL 705
Query: 379 RRLQEEIDQKQEEKEQLEAALELTRQQLGQATREAGAPGRAWGRQRLLQDRLVSVRATLC 438
+ L+++I +E K+QLE+ LE+ +Q+ Q + + +Q+LLQ+ LV +RA L
Sbjct: 706 QDLEDKIRALKENKDQLESVLEVLHRQMEQYRDQPQHLEKIAYQQKLLQEDLVHIRAELS 765
Query: 439 HLTQERERVWDTYSGLEQELGTLRETL-EYLLHLGSPQDRVSAQQQLWMVEDTLAGLGGP 497
+ E E W+ Y LE ++ L++TL E Q++ Q+ LW +ED AGL
Sbjct: 766 RESTEMENAWNEYLKLENDVEQLKQTLQEQHRRAFFFQEKSQIQKDLWRIEDVTAGLSAN 825
Query: 498 QK-----------PPPHTEPDSPSPVLQGEESSERESLPESLELSSP-RSP 536
++ P T P P P + +SE + P+ +SP R+P
Sbjct: 826 KENFRILVESVKNPERKTVPLFPHPPVPSLSTSESKPPPQPSPPTSPVRTP 876
Score = 33.9 bits (76), Expect = 0.59
Identities = 33/100 (33%), Positives = 42/100 (42%), Gaps = 19/100 (19%)
Query: 230 PDLFTPLSRPPSPLSLPRPRSAPARRPPA----PSGDTAPPARPHTPLSRIDVRPPLDWG 285
P L T S+PP P P ++P R P P T P RPH P R V PL
Sbjct: 853 PSLSTSESKPPPQ---PSPPTSPVRTPLEVRLFPQLQTYVPYRPHPPQLR-KVTSPL--- 905
Query: 286 PQRQTLSRPPTPRRGPPSEAGGGKPPRSPQHWSQEPRTQA 325
Q T ++P PP +PP P+ +S E + A
Sbjct: 906 -QSPTKAKPKVEDEAPP------RPP-LPELYSPEDQPPA 937
>gi|219689123 pleckstrin homology domain containing, family A member
5 isoform 2 [Homo sapiens]
Length = 1105
Score = 143 bits (361), Expect = 5e-34
Identities = 69/147 (46%), Positives = 101/147 (68%), Gaps = 3/147 (2%)
Query: 5 RPRSSLSLASSASTIS--SLSSLSPK-KPTRAVNKIHAFGKRGNALRRDPNLPVHIRGWL 61
RP S ++ AS+ + S ++ +SP + +RA K+H FGKR N+++R+PN PV RGWL
Sbjct: 9 RPISMINEASNYNVTSDYAVHPMSPVGRTSRASKKVHNFGKRSNSIKRNPNAPVVRRGWL 68
Query: 62 HKQDSSGLRLWKRRWFVLSGHCLFYYKDSREESVLGSVLLPSYNIRPDGPGAPRGRRFTF 121
+KQDS+G++LWK+RWFVLS CLFYY+D +EE +LGS+LLPS+ I R++ F
Sbjct: 69 YKQDSTGMKLWKKRWFVLSDLCLFYYRDEKEEGILGSILLPSFQIALLTSEDHINRKYAF 128
Query: 122 TAEHPGMRTYVLAADTLEDLRGWLRAL 148
A HP MRTY DT +++ W++A+
Sbjct: 129 KAAHPNMRTYYFCTDTGKEMELWMKAM 155
Score = 68.6 bits (166), Expect = 2e-11
Identities = 44/142 (30%), Positives = 70/142 (49%), Gaps = 7/142 (4%)
Query: 360 QSLETDTLLTKLCGQDRLLRRLQEEIDQKQEEKEQLEAALELTRQQLGQATREAGAPGRA 419
+ ++ D L++LC QD+++ L+E++ Q +EK LE AL Q++ A
Sbjct: 562 EEVDIDAKLSRLCEQDKVVHALEEKLQQLHKEKYTLEQALLSASQEIEMHADNPAAIQTV 621
Query: 420 WGRQRLLQDRLVSVRATLCHLTQERERVWDTYSGLEQELGTLRETL-EYLLHLGSPQ--- 475
++ LQ+ L+S L T E ER W Y LE ++ R + E L HLG Q
Sbjct: 622 VLQRDDLQNGLLSTCRELSRATAELERAWREYDKLEYDVTVTRNQMQEQLDHLGEVQTES 681
Query: 476 ---DRVSAQQQLWMVEDTLAGL 494
R Q++LW ++D + GL
Sbjct: 682 AGIQRAQIQKELWRIQDVMEGL 703
Score = 30.4 bits (67), Expect = 6.6
Identities = 12/22 (54%), Positives = 18/22 (81%)
Query: 582 APVARPRMSAQEQLERMRRNQE 603
A RPRM+ +EQ+ER+RR+Q+
Sbjct: 882 AESTRPRMTVEEQMERIRRHQQ 903
>gi|19923493 pleckstrin homology domain containing, family A member
5 isoform 1 [Homo sapiens]
Length = 1116
Score = 143 bits (361), Expect = 5e-34
Identities = 69/147 (46%), Positives = 101/147 (68%), Gaps = 3/147 (2%)
Query: 5 RPRSSLSLASSASTIS--SLSSLSPK-KPTRAVNKIHAFGKRGNALRRDPNLPVHIRGWL 61
RP S ++ AS+ + S ++ +SP + +RA K+H FGKR N+++R+PN PV RGWL
Sbjct: 117 RPISMINEASNYNVTSDYAVHPMSPVGRTSRASKKVHNFGKRSNSIKRNPNAPVVRRGWL 176
Query: 62 HKQDSSGLRLWKRRWFVLSGHCLFYYKDSREESVLGSVLLPSYNIRPDGPGAPRGRRFTF 121
+KQDS+G++LWK+RWFVLS CLFYY+D +EE +LGS+LLPS+ I R++ F
Sbjct: 177 YKQDSTGMKLWKKRWFVLSDLCLFYYRDEKEEGILGSILLPSFQIALLTSEDHINRKYAF 236
Query: 122 TAEHPGMRTYVLAADTLEDLRGWLRAL 148
A HP MRTY DT +++ W++A+
Sbjct: 237 KAAHPNMRTYYFCTDTGKEMELWMKAM 263
Score = 77.4 bits (189), Expect = 5e-14
Identities = 73/285 (25%), Positives = 118/285 (41%), Gaps = 42/285 (14%)
Query: 360 QSLETDTLLTKLCGQDRLLRRLQEEIDQKQEEKEQLEAALELTRQQLGQATREAGAPGRA 419
+ ++ D L++LC QD+++ L+E++ Q +EK LE AL Q++ A
Sbjct: 631 EEVDIDAKLSRLCEQDKVVHALEEKLQQLHKEKYTLEQALLSASQEIEMHADNPAAIQTV 690
Query: 420 WGRQRLLQDRLVSVRATLCHLTQERERVWDTYSGLEQELGTLRETL-EYLLHLGSPQ--- 475
++ LQ+ L+S L T E ER W Y LE ++ R + E L HLG Q
Sbjct: 691 VLQRDDLQNGLLSTCRELSRATAELERAWREYDKLEYDVTVTRNQMQEQLDHLGEVQTES 750
Query: 476 ---DRVSAQQQLWMVEDTLAGLG---------------------------GPQKPPPHTE 505
R Q++LW ++D + GL GP +E
Sbjct: 751 AGIQRAQIQKELWRIQDVMEGLSKHKQQRGTTEIGMIGSKPFSTVKYKNEGPDYRLYKSE 810
Query: 506 PDSPSPVLQGEESSERESLPES-LELSSPRSPETDWG------RPPGGDKDLASPHLGLG 558
P+ + E + E +S P S +E S + G + P + + ++ L
Sbjct: 811 PELTTVAEVDESNGEEKSEPVSEIETSVVKGSHFPVGVVPPRAKSPTPESSTIASYVTLR 870
Query: 559 SPRVSRASSPEGRHLPSPQLGTKAPVARPRMSAQEQLERMRRNQE 603
+ E QL A RPRM+ +EQ+ER+RR+Q+
Sbjct: 871 KTKKMMDLRTERPRSAVEQL-CLAESTRPRMTVEEQMERIRRHQQ 914
>gi|37595548 phosphoinositol 3-phosphate-binding protein-3 [Homo
sapiens]
Length = 1048
Score = 143 bits (361), Expect = 5e-34
Identities = 103/317 (32%), Positives = 145/317 (45%), Gaps = 26/317 (8%)
Query: 3 GSRPRSSLSLASSASTISSLSSLSPK-KPTRAVNKIHAFGKRGNALRRDPNLPVHIRGWL 61
G RP ++ S + + +S + P + TR K AFGKR ++++R+PN PV GWL
Sbjct: 7 GKRPATTNSDIPNHNMVSEVPPERPSVRATRTARKAVAFGKRSHSMKRNPNAPVTKAGWL 66
Query: 62 HKQDSSGLRLWKRRWFVLSGHCLFYYKDSREESVLGSVLLPSYNIRPDGPGAPRGRRFTF 121
KQ SSG++ W +RWFVL CLFYYKD +EES+LGS+ L S+ + P R+ TF
Sbjct: 67 FKQASSGVKQWNKRWFVLVDRCLFYYKDEKEESILGSIPLLSFRVAAVQPSDNISRKHTF 126
Query: 122 TAEHPGMRTYVLAADTLEDLRGWLRALGRASRAEGDDYGQPRSPARPQPGEGPGGPGGPP 181
AEH G+RTY +A++ E+ W++A+G A+R + + A E P PP
Sbjct: 127 KAEHAGVRTYFFSAESPEEQEAWIQAMGEAARVQIPPAQKSVPQAVRHSHEKPDSENVPP 186
Query: 182 EVSRGEEGRIS-ESPEVTRLSRGRGRPRLLTPSPTTDLHSGLQMRRARSPDLFTPLSRPP 240
+ S PE +RG G R G + + R P+ PP
Sbjct: 187 SKHHQQPPHNSLPKPEPEAKTRGEGDGR------------GCE-KAERRPERPEVKKEPP 233
Query: 241 SPLSLPRPRSAPARRPPAPSGDTAPPARPHTPLSRIDVRPPLDWGPQRQTLSRP-PTPRR 299
+ PA PA + P P P P W Q + SRP T
Sbjct: 234 -----VKANGLPAGPEPASEPGSPYPEGPRVPGGGEQPAQPNGW--QYHSPSRPGSTAFP 286
Query: 300 GPPSEAGGGK---PPRS 313
E GG + PPR+
Sbjct: 287 SQDGETGGHRRSFPPRT 303
Score = 80.1 bits (196), Expect = 7e-15
Identities = 86/347 (24%), Positives = 138/347 (39%), Gaps = 37/347 (10%)
Query: 287 QRQTLSRPPTPRRGPPSEAGGGKPPRSPQHWSQEPRTQAHSGSPTYLQLPPRPPGT---- 342
Q ++ S P +P +G S A P RSP S + +LPPR
Sbjct: 450 QPRSHSVPRSPSQGSYSRARIYSPVRSP--------------SARFERLPPRSEDIYADP 495
Query: 343 -----RASMVLLPGPPLESTFHQSL--------ETDTLLTKLCGQDRLLRRLQEEIDQKQ 389
R S+ PP F SL +TD LL KLC Q++++R + Q +
Sbjct: 496 AAYVMRRSISSPKVPPYPEVFRDSLHTYKLNEQDTDKLLGKLCEQNKVVREQDRLVQQLR 555
Query: 390 EEKEQLEAALELTRQQLGQATREAGAPGRAWGRQRLLQDRLVSVRATLCHLTQERERVWD 449
EKE LE+AL T Q+L + P + ++ LQ++L+++R L T
Sbjct: 556 AEKESLESALMGTHQELEMFGSQPAYPEKLRHKKDSLQNQLINIRVELSQATTALTNSTI 615
Query: 450 TYSGLEQELGTLRETLEYLLHLGSPQDRVS--AQQQLWMVEDTLAGLGGPQKPPPHTEPD 507
Y LE E+ L + L L+L + + ++ Q+++W ++D + GL P T+
Sbjct: 616 EYEHLESEVSALHDDLWEQLNLDTQNEVLNRQIQKEIWRIQDVMEGL-RKNNPSRGTDTA 674
Query: 508 SPSPVLQGEESSERESLPESLELSSPRSPETDWGRPPGGDKDLASPHLGLGSPRVSRASS 567
L + S L +S SP + + G P G P+ + S
Sbjct: 675 KHRGGLGPSATYSSNSPASPLSSASLTSPLSPFSLVSGSQGSPTKP--GSNEPKANYEQS 732
Query: 568 PEGRHLPSPQLGTKAPVARPRMSAQEQLERMRRNQECGRPFPRPTSP 614
+ H P L T ++ + + E+ + G PR SP
Sbjct: 733 KKDPHQTLP-LDTPRDISLVPTRQEVEAEKQAALNKVGVVPPRTKSP 778
Score = 34.7 bits (78), Expect = 0.35
Identities = 60/249 (24%), Positives = 94/249 (37%), Gaps = 32/249 (12%)
Query: 493 GLGGPQKPPPHTEPDSPSPVLQGEESSERESLPES-------LELSSPRSPETDWGRPPG 545
GL ++P P + EE +R +S L P SP D P
Sbjct: 799 GLSSQERPKSAVFPGEGKVKMSVEEQIDRMRRHQSGSMREKRRSLQLPASPAPDPSPRPA 858
Query: 546 GDKDLASPHLGLGSPRVS------RASSPEGRHLPSPQLGTKAPVARPR-MSAQEQLERM 598
+ H + +S RA P G +P + +AR R M + Q +
Sbjct: 859 --YKVVRRHRSIHEVDISNLEAALRAEEPGGHAYETP----REEIARLRKMELEPQHYDV 912
Query: 599 RRNQECGRPFPRPTSPRLLTL--GRTLSPAR---RQPDVEQ-RPVVGHSGAQKW--LRSS 650
N+E P R + L LSP +Q VE+ + ++ S Q +
Sbjct: 913 DINKELSTPDKVLIPERYIDLEPDTPLSPEELKEKQKKVERIKTLIAKSSMQNVVPIGEG 972
Query: 651 GSWSSPRNTTPYLPTSEGHRERVLSLSQALATEASQWHRMMTGGNLDSQGDPLPGVPLPP 710
S P+++ L +E+ + +S ALATEAS+ RM++ P P PP
Sbjct: 973 DSVDVPQDSESQLQ----EQEKRIEISCALATEASRRGRMLSVQCATPSPPTSPASPAPP 1028
Query: 711 SDPTRQETP 719
++P E+P
Sbjct: 1029 ANPLSSESP 1037
>gi|188497618 connector enhancer of kinase suppressor of Ras 1 [Homo
sapiens]
Length = 713
Score = 66.6 bits (161), Expect = 8e-11
Identities = 61/212 (28%), Positives = 91/212 (42%), Gaps = 41/212 (19%)
Query: 59 GWLHKQDSSGLRL---WKRRWFVLSGHCLFYYKDSREESVLGSVLLPSYNIRPDGPGAPR 115
GWL + + G + W+RRWFVL GH L++Y+ ++E G + + +Y++ G +
Sbjct: 401 GWLLLRKAPGGFMGPRWRRRWFVLKGHTLYWYRQPQDEKAEGLINVSNYSLE---SGHDQ 457
Query: 116 GRRFTFTAEHPGMRTYVLAADTLEDLRGWLRAL----------GRA---------SRAEG 156
+++ F H + ++ AADTL DL W+R L GRA S E
Sbjct: 458 KKKYVFQLTHDVYKPFIFAADTLTDLSMWVRHLITCISKYQSPGRAPPPREEDCYSETEA 517
Query: 157 DD-------YGQPRSPARP-QPGEGPGGPGGPP--EVSRGEEGRISESPE-----VTRLS 201
+D + SPA+ P G P P R G +++S E + R
Sbjct: 518 EDPDDEAGSHSASPSPAQAGSPLHGDTSPAATPTQRSPRTSFGSLTDSSEEALEGMVRGL 577
Query: 202 RGRGRPRLLTPSP-TTDLHSGLQMRRARSPDL 232
R G L P P T + MRR R P L
Sbjct: 578 RQGGVSLLGQPQPLTQEQWRSSFMRRNRDPQL 609
>gi|24432056 hypothetical protein LOC144717 [Homo sapiens]
Length = 249
Score = 65.5 bits (158), Expect = 2e-10
Identities = 66/231 (28%), Positives = 91/231 (39%), Gaps = 39/231 (16%)
Query: 54 PVHIRGWLHKQDSSGLRLWKRRWFVLSGHCLFYYKDSREESVLGSVLLPSYNIRPDGPGA 113
PV G+L+K+ + RRWFVL G+ LFY++D+ +G ++L +
Sbjct: 17 PVDNAGFLYKKGGRHAA-YHRRWFVLRGNMLFYFEDAASREPVGVIILEGCTVEL----V 71
Query: 114 PRGRRFTFTAEHPG--MRTYVLAADTLEDLRGWLRALGRASRAEGDDYGQPRSPARPQPG 171
F F G RTYVLAA++ + + GW++AL RAS + R R
Sbjct: 72 EAAEEFAFAVRFAGTRARTYVLAAESQDAMEGWVKALSRAS------FDYLRLVVRELEQ 125
Query: 172 EGPGGPGGPPEVSRGEEGRISESPEVTRLSRGRGRPRLLTPSPTTDLHSGLQMRRARSPD 231
+ RG G P+ L P L P P+ + A +P
Sbjct: 126 Q--------LAAVRGGGGMALPQPQPQSLPLPPSLPSALAPVPS--------LPSAPAPV 169
Query: 232 LFTPLSRPPSPLSLPRPR-----SAPARRPPAPSGDTAPPAR----PHTPL 273
PL R PS L P+ S A P P PP R PH PL
Sbjct: 170 PALPLPRRPSALP-PKENGCAVWSTEATFRPGPEPPPPPPRRRASAPHGPL 219
Score = 35.0 bits (79), Expect = 0.27
Identities = 26/78 (33%), Positives = 30/78 (38%), Gaps = 3/78 (3%)
Query: 240 PSPLSLPRPRSAPARRPPAPSGDTAPPARPHTPL-SRIDVRPPLDWGPQRQTLSRP--PT 296
P P SLP P S P+ P PS +AP P PL R PP + G + P
Sbjct: 141 PQPQSLPLPPSLPSALAPVPSLPSAPAPVPALPLPRRPSALPPKENGCAVWSTEATFRPG 200
Query: 297 PRRGPPSEAGGGKPPRSP 314
P PP P P
Sbjct: 201 PEPPPPPPRRRASAPHGP 218
>gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo
sapiens]
Length = 748
Score = 63.5 bits (153), Expect = 7e-10
Identities = 36/103 (34%), Positives = 51/103 (49%), Gaps = 15/103 (14%)
Query: 59 GWLHKQDSSGLRLWKRRWFVLSGHCLFYYKDSREESVLGSVLLPSYNI-----RPDGPG- 112
GWL KQ ++ W RWFVL G L+Y+KD E LG++ LP + + PG
Sbjct: 24 GWLRKQGGF-VKTWHTRWFVLKGDQLYYFKDEDETKPLGTIFLPGNKVSEHPCNEENPGK 82
Query: 113 -----APRGRRFTFTAEHPGMRTYVLAADTLEDLRGWLRALGR 150
P G R TA H +Y+L A T D+ W++++ R
Sbjct: 83 FLFEVVPGGDRDRMTANH---ESYLLMASTQNDMEDWVKSIRR 122
>gi|194733753 phosphoinositide-binding protein PIP3-E isoform 1
[Homo sapiens]
Length = 438
Score = 62.8 bits (151), Expect = 1e-09
Identities = 46/189 (24%), Positives = 77/189 (40%), Gaps = 13/189 (6%)
Query: 58 RGWLHKQDSSGLRL---WKRRWFVLSGHCLFYYKDSREESVLGSVLLPSYNIRPDGPGAP 114
+GWL+K+ G L WK+ W +L G L++Y + E G V LP + + +
Sbjct: 46 QGWLYKKKEKGSFLSNKWKKFWVILKGSSLYWYSNQMAEKADGFVNLPDFTVE---RASE 102
Query: 115 RGRRFTFTAEHPGMRTYVLAADTLEDLRGWLRALGRA------SRAEGDDYGQPRSPARP 168
++ F HP ++T+ AA+ ++++ WL LG A + + + Y +
Sbjct: 103 CKKKHAFKISHPQIKTFYFAAENVQEMNVWLNKLGSAVIHQESTTKDEECYSESEQEDPE 162
Query: 169 QPGEGPGGPGGPPEVSRGEEGRISESPEVTRLSRGRGRPRLLTPSPTTDLHSGLQMRRAR 228
E P P S + S SP ++ S +P++ S L R
Sbjct: 163 IAAETPPPPHASQTQSLTAQQASSSSPSLSGTSYSFSSLENTVKTPSS-FPSSLSKERQS 221
Query: 229 SPDLFTPLS 237
PD LS
Sbjct: 222 LPDTVNSLS 230
>gi|194733747 phosphoinositide-binding protein PIP3-E isoform 1
[Homo sapiens]
Length = 438
Score = 62.8 bits (151), Expect = 1e-09
Identities = 46/189 (24%), Positives = 77/189 (40%), Gaps = 13/189 (6%)
Query: 58 RGWLHKQDSSGLRL---WKRRWFVLSGHCLFYYKDSREESVLGSVLLPSYNIRPDGPGAP 114
+GWL+K+ G L WK+ W +L G L++Y + E G V LP + + +
Sbjct: 46 QGWLYKKKEKGSFLSNKWKKFWVILKGSSLYWYSNQMAEKADGFVNLPDFTVE---RASE 102
Query: 115 RGRRFTFTAEHPGMRTYVLAADTLEDLRGWLRALGRA------SRAEGDDYGQPRSPARP 168
++ F HP ++T+ AA+ ++++ WL LG A + + + Y +
Sbjct: 103 CKKKHAFKISHPQIKTFYFAAENVQEMNVWLNKLGSAVIHQESTTKDEECYSESEQEDPE 162
Query: 169 QPGEGPGGPGGPPEVSRGEEGRISESPEVTRLSRGRGRPRLLTPSPTTDLHSGLQMRRAR 228
E P P S + S SP ++ S +P++ S L R
Sbjct: 163 IAAETPPPPHASQTQSLTAQQASSSSPSLSGTSYSFSSLENTVKTPSS-FPSSLSKERQS 221
Query: 229 SPDLFTPLS 237
PD LS
Sbjct: 222 LPDTVNSLS 230
>gi|40354212 phosphoinositide-binding protein PIP3-E isoform 2 [Homo
sapiens]
Length = 437
Score = 62.8 bits (151), Expect = 1e-09
Identities = 46/189 (24%), Positives = 77/189 (40%), Gaps = 13/189 (6%)
Query: 58 RGWLHKQDSSGLRL---WKRRWFVLSGHCLFYYKDSREESVLGSVLLPSYNIRPDGPGAP 114
+GWL+K+ G L WK+ W +L G L++Y + E G V LP + + +
Sbjct: 45 QGWLYKKKEKGSFLSNKWKKFWVILKGSSLYWYSNQMAEKADGFVNLPDFTVE---RASE 101
Query: 115 RGRRFTFTAEHPGMRTYVLAADTLEDLRGWLRALGRA------SRAEGDDYGQPRSPARP 168
++ F HP ++T+ AA+ ++++ WL LG A + + + Y +
Sbjct: 102 CKKKHAFKISHPQIKTFYFAAENVQEMNVWLNKLGSAVIHQESTTKDEECYSESEQEDPE 161
Query: 169 QPGEGPGGPGGPPEVSRGEEGRISESPEVTRLSRGRGRPRLLTPSPTTDLHSGLQMRRAR 228
E P P S + S SP ++ S +P++ S L R
Sbjct: 162 IAAETPPPPHASQTQSLTAQQASSSSPSLSGTSYSFSSLENTVKTPSS-FPSSLSKERQS 220
Query: 229 SPDLFTPLS 237
PD LS
Sbjct: 221 LPDTVNSLS 229
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 61.2 bits (147), Expect = 3e-09
Identities = 74/232 (31%), Positives = 84/232 (36%), Gaps = 48/232 (20%)
Query: 164 SPARPQPGEGPGGPGGPPEVSR----GEEGRISESPEVTRLSRGRGRPRL--------LT 211
SP P P E P P PPE SR EE S PE LSR L L+
Sbjct: 447 SPLSPPPEESPTSP--PPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLS 504
Query: 212 PSPTTDLHSGLQM-------RRARSPDLFTPLSRPP--SPLS--------LPRPRSAPAR 254
P P + S L+ SP L TPLS PP SPLS P P P
Sbjct: 505 PPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTS 564
Query: 255 RPPAPSGDTAPPARPHTPLSRIDVRPPLDWGPQRQTLSRP-------PTPRR---GPPSE 304
PP S + PP +P+S P+ P+ L P P P PP E
Sbjct: 565 PPPEASRLSPPP--EESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPE 622
Query: 305 AGGGKPPRSPQHWSQEPRTQAHSGSPTYLQLPPRPPGTRASMVLLPGPPLES 356
A PP S P S P +L P P +R L PP ES
Sbjct: 623 ASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSR-----LSPPPEES 669
Score = 53.9 bits (128), Expect = 6e-07
Identities = 138/568 (24%), Positives = 192/568 (33%), Gaps = 88/568 (15%)
Query: 164 SPARPQPGEGPGGPGGPPEVSRGEEGRISESPEVTRLSRGRGRPRLLTPSPTTDLHSGLQ 223
SP P E P P PPE E S PE +RLS + P + + +
Sbjct: 543 SPLSPPFEESPLSP--PPE-----ELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPE 595
Query: 224 MRRARSPDLFTPLSRPP--SPLSLPRPRSAPARRPPAPSGDTAPPAR-PHTPLSRIDVRP 280
R P +PLS PP SPLS P P ++ PP S + PP P +P +
Sbjct: 596 ASRLFPPFEESPLSPPPEESPLS-PPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLS 654
Query: 281 PLDWGPQRQTLSRPP--TPRRGPPSEAGGGKPPRSPQHWSQEPRTQAHSGSPTYLQLPPR 338
PL P LS PP +P PP E+ PP + + P + SP P
Sbjct: 655 PL---PVVSRLSPPPEESPLSPPPEESPTSPPPEASR---LSPPPEDSPTSPPPEDSPAS 708
Query: 339 PPGTRASMVLLPGPPLESTFHQSLETDTLLTKLCGQDRLLRRLQEEIDQKQEEKEQLEAA 398
PP + M L P ES E L + G R + + + EE A
Sbjct: 709 PPPEDSLMSL---PLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQA 765
Query: 399 LELTRQQLGQATREAGAPGRAWGRQRLLQDRLVSVRATLCHLTQERERVWDTYSGLEQEL 458
E + P ++ +S +A HL+ + E + + E L
Sbjct: 766 EEPHLSPQPEEPCLCAVP----------EEPHLSPQAEGPHLSPQPEELHLSPQTEEPHL 815
Query: 459 GTLRETLEYLLHLGSPQDRVSAQQQLWMVEDTLAGLGGPQKPPPHTEPDSPSPVLQGEES 518
+ E E L + +S Q + E L+ P+ H P+ P L S
Sbjct: 816 SPVPE--EPCLSPQPEESHLSPQSE----EPCLS----PRPEESHLSPELEKPPL----S 861
Query: 519 SERESLPESLELSSPRSPETDWGRPPGGDKDLASPHLGLGSPRVSRASSPEGRHLPSPQL 578
E PE E +PE PP G+ L+ LG P +S P P P+
Sbjct: 862 PRPEKPPE--EPGQCPAPEELPLFPPPGEPSLSPL---LGEPALSEPGEPP--LSPLPEE 914
Query: 579 GTKAPVARPRMSAQEQLERMRRNQECGRPFPRPTSPRLLTLGRTLSPARRQPDVEQRPVV 638
+P P +S Q P P P L + +P P E
Sbjct: 915 LPLSPSGEPSLSPQLMP-------------PDPLPPPLSPIITAAAPPALSPLGELEYPF 961
Query: 639 GHSGAQKWLRSSGSWSSPRNTTPYLPTSEGHRERVLSLSQALATEASQWHRMMTGGNLDS 698
G G ++P TP P E A T+ M+
Sbjct: 962 GAKGDSD---PESPLAAPILETPISPPPE-----------ANCTDPEPVPPMIL------ 1001
Query: 699 QGDPLPGVPLPPSDPTRQETPPPRSPPV 726
P PG P+ P+ P E PP+ P+
Sbjct: 1002 --PPSPGSPVGPASPILMEPLPPQCSPL 1027
Score = 42.7 bits (99), Expect = 0.001
Identities = 54/176 (30%), Positives = 69/176 (39%), Gaps = 42/176 (23%)
Query: 162 PRSPAR----PQPGEGPGGPGGPPEVSRGEEGRISES-PE-------------------- 196
P SPAR P+ GE G PGG +G EG+ ++ P+
Sbjct: 4820 PESPARAGTEPKKGEAEG-PGGK---EKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQLDI 4875
Query: 197 VTRLSRGRGRPRLLTPSPTTDLHSGLQMRRARSPDLFTPLSRPPSPLSLPRPRSAPARRP 256
++ L + P T T S L +R+ +P P S PPSPL+ P P S P
Sbjct: 4876 LSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEP-SPPPSPLA-PSPASPPTE-- 4931
Query: 257 PAPSGDTAPPARPHTPLSRIDVRPPLDWGPQRQTLSRPPTPRRGPPSEAGGGKPPR 312
P T P A P P PL P+ S P PR PP E +PPR
Sbjct: 4932 PLVELPTEPLAEPPVPSPL-----PLASSPE----SARPKPRARPPEEGEDSRPPR 4978
Score = 42.0 bits (97), Expect = 0.002
Identities = 68/241 (28%), Positives = 91/241 (37%), Gaps = 68/241 (28%)
Query: 157 DDYGQPRSP-----ARPQ-PGEGPGGPGGPPEVSRGEEGRISESPEVTRLSRGRGRPRLL 210
D + +PR P A P+ PG G GG P +S G ++ EV + G P
Sbjct: 2242 DPFLKPRCPSLDNLAVPESPGVG-GGKASEPLLSPPPFGESRKALEVKKEELGASSPSYG 2300
Query: 211 TP------SPTTDLH-SGLQMRRARSPDLF-TPLS---------------RP-------- 239
P SP++ H GL+++ +PD+F PL+ RP
Sbjct: 2301 PPNLGFVDSPSSGTHLGGLELK---TPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQA 2357
Query: 240 --PSPLSLP-------------RPRSAPARRPPAPSGDTAPPAR--PHTPLSRIDVRPPL 282
PSP S P +P P +PP P A P R P P SR+
Sbjct: 2358 LAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPA---- 2413
Query: 283 DWGPQRQTLSRPPTPRRGPPSEAGGGKP--PR--SPQHWSQEPRTQAHSGSPTYLQLPPR 338
PQ Q+ S+ P R +EA P PR SP +S+ P L PPR
Sbjct: 2414 --SPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPR 2471
Query: 339 P 339
P
Sbjct: 2472 P 2472
Score = 41.6 bits (96), Expect = 0.003
Identities = 42/120 (35%), Positives = 50/120 (41%), Gaps = 15/120 (12%)
Query: 235 PLSRPP--SPLSLPRPRSAPARRPPAPSGDTAPPAR-PHTPL------SRIDVRPPLDWG 285
PL PP SPLS P P +P PP S + PP P +PL SR PL
Sbjct: 439 PLLPPPEESPLS-PPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPP 497
Query: 286 PQRQTLSRPPTPRRGPPSEAGGGKPP-RSPQHWSQE----PRTQAHSGSPTYLQLPPRPP 340
P+ LS PP P E PP SP + E P +A SP + + P PP
Sbjct: 498 PEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPP 557
Score = 41.6 bits (96), Expect = 0.003
Identities = 60/222 (27%), Positives = 80/222 (36%), Gaps = 30/222 (13%)
Query: 153 RAEGDDYGQPRSPARPQPGEGPGGPGGPPEVSRGEEGRISESPEVTRLSRGRGRPRL--- 209
R+EG P RP+ P P + EE +S PE L P L
Sbjct: 737 RSEG-----PHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQ 791
Query: 210 -----LTPSPTTDLHSGLQMRRAR-SPDLFTPLSRPPSPLSLPRPRSAPARRPPAPSGDT 263
L+P P +LH Q SP P P S P+S P P
Sbjct: 792 AEGPHLSPQPE-ELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESH 850
Query: 264 APPARPHTPLSRIDVRPPLDWG----PQRQTLSRPP-----TPRRGPPSEAGGGKPPRSP 314
P PLS +PP + G P+ L PP +P G P+ + G+PP SP
Sbjct: 851 LSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSP 910
Query: 315 QHWSQEPRTQAHSGSPTYLQ--LPPRP-PGTRASMVLLPGPP 353
E + SG P+ +PP P P + ++ PP
Sbjct: 911 ---LPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPP 949
Score = 40.4 bits (93), Expect = 0.006
Identities = 51/213 (23%), Positives = 78/213 (36%), Gaps = 24/213 (11%)
Query: 226 RARSPDLFTPLSRPPSPLSLPRPRSA---PARRPPAPSGDTAPPARPHTPLSRIDVRPPL 282
R P P RPP PR A P +P G P +P P +
Sbjct: 3087 RGVEPGPLGPEERPPPAADASEPRLASVLPEVKPKVEEGGRHP-----SPCQFTIATPKV 3141
Query: 283 DWGPQRQTLS---RPPTPRRGPPSEAGGGKPPRSPQHWSQEPRTQAHSGSPTYLQLPPRP 339
+ P +L +P G G P S H +++ A G P +L P
Sbjct: 3142 EPAPAANSLGLGLKPGQSMMGSRDTRMGTGPFSSSGHTAEKASFGATGGPPAHLLTPSPL 3201
Query: 340 PGTRASMVL-----------LPGPPLESTFH-QSLETDTLLTKL-CGQDRLLRRLQEEID 386
G S +L LPG P S +E+ + ++L + LL ++E+
Sbjct: 3202 SGPGGSSLLEKFELESGALTLPGGPAASGDELDKMESSLVASELPLLIEDLLEHEKKELQ 3261
Query: 387 QKQEEKEQLEAALELTRQQLGQATREAGAPGRA 419
+KQ+ QL+ A + +QQ + A P +A
Sbjct: 3262 KKQQLSAQLQPAQQQQQQQQQHSLLSAPGPAQA 3294
Score = 39.3 bits (90), Expect = 0.014
Identities = 66/288 (22%), Positives = 119/288 (41%), Gaps = 61/288 (21%)
Query: 379 RRLQEEIDQKQEEKEQLEAALELTRQQLGQATREAGAPGRAWGRQRLLQDRLVSVRATLC 438
++LQ++ +Q++++QL+ +L +QQL Q ++ Q+L Q + ++
Sbjct: 3904 QQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQ----------QQLQQQQQQQLQQQQQ 3953
Query: 439 HLTQERERVWDTY--SGLEQELGTLRETLEYLLHLGSPQDRVSAQQQLWMVEDTLAGLGG 496
L Q++++ + +Q++G L ++ L SPQ QQQ + G G
Sbjct: 3954 QLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLL----SPQQ----QQQ----QQVALGPGM 4001
Query: 497 PQKPPPH-TEPDSPSPVLQGEESSERESLPESLELSSPRSPETDWGRPPGGDKDLASPHL 555
P KP H + P + P L E+ ++ ++ + P T G P L
Sbjct: 4002 PAKPLQHFSSPGALGPTLL-LTGKEQNTVDPAVSSEATEGPSTHQGGP-----------L 4049
Query: 556 GLGSPRVSRASSPEGRHLPSPQLGTKAPVARPRMSAQEQLERMRRNQECGRPFPRPTSPR 615
+G+ S A+ P +P +S QL ++ +P P+P+S +
Sbjct: 4050 AIGTTPESMATEP--------------GEVKPSLSGDSQLLLVQ-----PQPQPQPSSLQ 4090
Query: 616 LLTLGRTLSPARRQPDVEQRPVVGHSGAQKWLRSSGSWSSPRNTTPYL 663
L R P ++Q V G G SGS SS ++ P+L
Sbjct: 4091 LQPPLRL--PGQQQQQVSLLHTAG--GGSHGQLGSGS-SSEASSVPHL 4133
Score = 38.5 bits (88), Expect = 0.024
Identities = 72/264 (27%), Positives = 99/264 (37%), Gaps = 40/264 (15%)
Query: 165 PARPQP----GEGPGGPGGPPEVSRGE---EGRISESPEVTRLSRGRGRP-------RLL 210
P +P P G+G G G P V + +G ++++P++ LS + + R L
Sbjct: 4172 PPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQL 4231
Query: 211 TPSPTTDLHSGLQMRRARSPDLFTPLSRPPSPLSLPRPRSAPARRPPAPSGDTAPPARPH 270
S Q ++ L L P P P++ P + A PP P
Sbjct: 4232 QQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPA 4291
Query: 271 TPLSRIDVRPPLDWGPQRQTLSRPPTPRRGPPSEAGGGKPPRSPQHWSQEPRTQAHSGSP 330
P + P L GP PTP PPS P+ P+ SQ P S P
Sbjct: 4292 PP-GALSTGPVL--GPVH------PTP---PPSS------PQEPKRPSQLPSPS--SQLP 4331
Query: 331 TYLQLPPRPPGT-RASMVLLPGPPLESTFHQSLETDTLLTKLCGQDRLLRRLQEEIDQKQ 389
T QLPP PGT + L PP + + DTL +K G L E QK
Sbjct: 4332 TEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAE--TQKP 4389
Query: 390 EEKEQLEAALELTRQQLGQATREA 413
E+ + L+ Q GQ EA
Sbjct: 4390 EQSSLVPGHLD---QVNGQVVPEA 4410
Score = 38.1 bits (87), Expect = 0.032
Identities = 70/279 (25%), Positives = 90/279 (32%), Gaps = 24/279 (8%)
Query: 497 PQKPPPHTEPDSPSP----VLQGEESSERESLPESLELSSPRSPETDWGRPPGGDKDLAS 552
P PPP P SP P + E LPE+L LS P E+ PP
Sbjct: 448 PLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLE-ESPLSPPPEESPLSPP 506
Query: 553 PHLGLGSPRVSRASSPEGRHLPSPQLGT---KAPVARPRMSAQEQLERMRRNQECGRPFP 609
P SP SP PSP L T P A P E+ +E P
Sbjct: 507 PESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEE----LP 562
Query: 610 RPTSPRLLTLGRTLSPARRQPDVEQRPVVGHSGAQKWLR--SSGSWSSPRNTTPYLPTSE 667
P L + P E+ P+ A + S P +P P E
Sbjct: 563 TSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPE 622
Query: 668 GHRERVLSLSQALATEASQWHRMMTGGNLDSQGDPLPGVP--LPPSDPTRQETPPPRSPP 725
R ++ + M+ S+ PLP V PP + + PP SP
Sbjct: 623 ASRLSPPPEDSPMSPPPEE--SPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESP- 679
Query: 726 VANSGSTGFSRRGSGRGGGPTPWGPAWDAGIAPPVLPQD 764
S SR PT P D+ +PP P+D
Sbjct: 680 --TSPPPEASRLSPPPEDSPTS-PPPEDSPASPP--PED 713
Score = 37.4 bits (85), Expect = 0.054
Identities = 109/474 (22%), Positives = 164/474 (34%), Gaps = 91/474 (19%)
Query: 325 AHSGSPTYLQLPPRPPGTRASMVLLPGPPLESTFHQSLETDTLLTKLCGQDRLLRRLQEE 384
+HSG P +L +P G+ + + Q + +L Q +L ++ ++
Sbjct: 3882 SHSGQP---KLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQ-----QLQQQQQLQQQQLQQ 3933
Query: 385 IDQKQEEKEQLEAALELTRQQLGQATREAGAPGRAWGRQRLLQDRLVSVRATLCHLTQER 444
Q+Q+ ++Q + L+ +QQL Q ++ + +Q+ Q L++ TL Q++
Sbjct: 3934 QQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQ--QQQQQQMGLLNQSRTLLSPQQQQ 3991
Query: 445 ERVWDTYSGLE----QELGTLRETLEYLLHLGSPQDRVSAQQQLWMVEDTLAGLGGP--- 497
++ G+ Q + LL G Q+ V E GGP
Sbjct: 3992 QQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAI 4051
Query: 498 --QKPPPHTEPDSPSPVLQGEE-----SSERESLPESLELSSPRSPETDWGRPPGGDKDL 550
TEP P L G+ + + P SL+L P R PG +
Sbjct: 4052 GTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPL-------RLPGQQQQQ 4104
Query: 551 AS--------PHLGLGSPRVSRASS-PEGRHLPSPQLGTKAPVARPRMSAQEQ--LERMR 599
S H LGS S ASS P PS LG + + +Q LER
Sbjct: 4105 VSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPM 4164
Query: 600 RNQECGRPFPRPTSPRLLTLGRTLSPARRQPDVEQRPVVGHSGAQKWLRSSGSWSSPRNT 659
+N +P P+P G L + P V P VG AQ
Sbjct: 4165 QNNTGPQP-PKP--------GPVLQSGQGLPGVGIMPTVGQLRAQ--------------- 4200
Query: 660 TPYLPTSEGHRERVLSLSQALATEASQWHRMMTGGNLDSQGDPLPGVPLPPSDPTRQETP 719
+ VL+ + L + Q + + + Q L S RQ TP
Sbjct: 4201 ----------LQGVLAKNPQLRHLSPQQQQQLQALLMQRQ--------LQQSQAVRQ-TP 4241
Query: 720 PPRSPPVANSGSTGFSRRGSGRGGGPTP-WGPAWDAGI-----APPVLPQDEGA 767
P + P S G GG P P GP + G PP LP GA
Sbjct: 4242 PYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGA 4295
Score = 36.6 bits (83), Expect = 0.092
Identities = 73/288 (25%), Positives = 101/288 (35%), Gaps = 33/288 (11%)
Query: 157 DDYGQPRSPARPQPGEGPGGPGGPPEVSRGEEGRISESPEVTRLSRGRGRPRLLTPSPTT 216
D Y +P P+RPQ + PP E + S T L G G P L P
Sbjct: 2448 DPYSRP--PSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAG-GFPAALPAGPAG 2504
Query: 217 DLH----SGLQMRRARSPDLFTPLSRP-PSPLSLPRPRSAPARRPPAPSGDTAPPARPHT 271
+LH SG RSP + P P + P+ P+ +PP P P PH
Sbjct: 2505 ELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPP---PHG 2561
Query: 272 PLSRIDVRPPLDWGPQRQTLS------RPPTPRRGPPSEAGGGKPPRSPQHWSQEPRTQA 325
S P L PQ + P GP S + G SP A
Sbjct: 2562 INSHFGPGPTLG-KPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPA 2620
Query: 326 HSGSPTYLQLPPRPPGTRASMVLLPGPPLESTFHQSLETDTLLTKLCG-QDRLLRRLQEE 384
GS YL ++ S + P E + + +L G QD + L +
Sbjct: 2621 PDGSLPYLS----HGASQRSGITSPVEKREDP-GTGMGSSLATAELPGTQDPGMSGLSQT 2675
Query: 385 IDQKQEEKEQLEAAL-------ELTRQQLGQATREAGA--PGRAWGRQ 423
+KQ ++++L L RQ+ A AGA P +WG +
Sbjct: 2676 ELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAE 2723
Score = 35.4 bits (80), Expect = 0.20
Identities = 79/320 (24%), Positives = 111/320 (34%), Gaps = 47/320 (14%)
Query: 473 SPQDRVSAQQQLWMVEDTLAGLGGPQKPPPHTEPDSPSPVLQGEESSERESLPESLELSS 532
SP VS L +V + L P + P + P SP E+S PE S
Sbjct: 645 SPPPEVSRLSPLPVV----SRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSP 700
Query: 533 PRSPETDWGRPPGGDKDLA-----SPHLGL-GSPRVSRASSPEGRHL-PSPQLGTKAPVA 585
P PE PP D ++ SP L L P++ S EG HL P P+
Sbjct: 701 P--PEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRS--EGPHLSPRPE-------- 748
Query: 586 RPRMSAQEQLERMRRNQECGRPFPRPTSPRLLTLGRT--LSPARRQPDVEQRPVVGHSGA 643
P +S + + + E P+P P L + LSP P + +P H
Sbjct: 749 EPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSP 808
Query: 644 QKWLRSSGSWSSPRNTTPYL-PTSEGHRERVLSLSQALATEASQWHRMMTGGNLDSQGDP 702
Q + SP P L P E S L+ + H + + + P
Sbjct: 809 Q----TEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHL-----SPELEKPP 859
Query: 703 L-PGVPLPPSDPTRQETP---PPRSPPVANSGSTGFSRRGSGRGGGP--------TPWGP 750
L P PP +P + P P PP S S G P P P
Sbjct: 860 LSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSP 919
Query: 751 AWDAGIAPPVLPQDEGAWPL 770
+ + ++P ++P D PL
Sbjct: 920 SGEPSLSPQLMPPDPLPPPL 939
Score = 32.3 bits (72), Expect = 1.7
Identities = 40/162 (24%), Positives = 55/162 (33%), Gaps = 24/162 (14%)
Query: 160 GQPRSPARPQPGEGPGGPGGPPEVSRGEEGRISESPEVTRLSRGRGRPRLLTPSPTTDLH 219
G+P P P P E P P G P +S P ++ + P L SP +L
Sbjct: 904 GEP--PLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPAL---SPLGELE 958
Query: 220 SGLQMRRARSPD-------LFTPLSRPPSPLSLPRPRSAPARRPPAPSGDTAPPARPHTP 272
+ P+ L TP+S PP P PP+P P P +P
Sbjct: 959 YPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGS----PVGPASP 1014
Query: 273 LSRIDVRPPLDWGPQRQTLSRPPTPRRGPPSEAGGGKPPRSP 314
+ + P L P+ PPS+ PP P
Sbjct: 1015 ILMEPLPPQCS-----PLLQHSLVPQNSPPSQC---SPPALP 1048
Score = 30.4 bits (67), Expect = 6.6
Identities = 38/128 (29%), Positives = 45/128 (35%), Gaps = 16/128 (12%)
Query: 227 ARSPDLFTPLSRPPSPLSLPRPRSAPARRPPAPSG-DTAPPARPHTPLSRIDVRPPLDWG 285
A P +PL P LS P P APA + G DTAP P S +P
Sbjct: 1085 ALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGS----QPEPGQT 1140
Query: 286 PQRQTLSRPPTPRRGPPSEAGGGKPPRSPQHWSQEPRTQAHSGSPTYLQLPPRPPGTRAS 345
P +P P E P +P E + A GSP Q PR P
Sbjct: 1141 PGSLASELKGSPVLLDPEELA----PVTPMEVYPECKQTAGQGSPCEEQEEPRAP----- 1191
Query: 346 MVLLPGPP 353
+ P PP
Sbjct: 1192 --VAPTPP 1197
Score = 30.4 bits (67), Expect = 6.6
Identities = 36/119 (30%), Positives = 46/119 (38%), Gaps = 26/119 (21%)
Query: 239 PPSPLSLPRPRSAPARRPPAPSGDTAPPARPHTPLSRIDVRPPLDWGPQRQTLSRPPTPR 298
P PL PR +AP PP PS AP +PP+ L P
Sbjct: 2181 PAYPLE-PRFPTAPPTYPPYPSPTGAP------------AQPPM--------LGASSRPG 2219
Query: 299 RGPPSEAGGGKPPRSPQHW--SQEPRTQAHSGSPTYLQLPPRP--PGTRASMVLLPGPP 353
G P E PP +P+H + +P + S L +P P G +AS LL PP
Sbjct: 2220 AGQPGEF-HTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPP 2277
Score = 30.4 bits (67), Expect = 6.6
Identities = 48/206 (23%), Positives = 65/206 (31%), Gaps = 33/206 (16%)
Query: 160 GQPRSPARPQPGEGPGGPGGPPEVSRGEEGRISES----------PEVTRLSRGRGRPRL 209
G P QPGE P G P + PE + G+ L
Sbjct: 2213 GASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPL 2272
Query: 210 LTPSPTTDLHSGLQMRR----ARSPDLFTP-LSRPPSPLSLPRPRSAPARRPPAPSGDTA 264
L+P P + L++++ A SP P L SP S + P
Sbjct: 2273 LSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLT 2332
Query: 265 PPARPHTPLSRIDVRPPLDWGPQRQTLSRPPTPRRGPPSEAGGGKPPRSPQHWSQEPRTQ 324
P A P S P L PQ PP++A PP P + T
Sbjct: 2333 PRASQVEPQS-----PGLGLRPQEP-----------PPAQALAPSPPSHPDIFRPGSYTD 2376
Query: 325 AHSGSPTYLQLPPRPPGTRASMVLLP 350
++ P L P+PP + L P
Sbjct: 2377 PYAQPP--LTPRPQPPPPESCCALPP 2400
Score = 30.4 bits (67), Expect = 6.6
Identities = 50/213 (23%), Positives = 73/213 (34%), Gaps = 26/213 (12%)
Query: 453 GLEQELGTLRETLEYLLHLGSPQDRVSAQQQ----LWMVEDTLAGLGGPQKPPPHTEPDS 508
G+ +G LR L+ +L +S QQQ +++ L ++ PP+ EP +
Sbjct: 4189 GIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGT 4248
Query: 509 PSPVLQGEESSERESLPESLELSSPRS---PETDWGRPPGGDKDLASPHLGLGSPRVSRA 565
+ LQG + P+ P++ E G P G L +P L + V
Sbjct: 4249 QTSPLQGLLGCQ----PQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGP 4304
Query: 566 SSPEGRHLPSPQLGTKAPVARPRMSAQEQLERMRRNQECGRPFPRPTSPRLLTLGRTLSP 625
P PS K P P S+Q E G P P+ G TL P
Sbjct: 4305 VHPTPP--PSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQ---------GPTLEP 4353
Query: 626 ARRQPDVEQRPVVGHSGAQKWLRSSGSWSSPRN 658
P P + + G W P N
Sbjct: 4354 ----PPGRVSPAAAQLADTLFSKGLGPWDPPDN 4382
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 60.5 bits (145), Expect = 6e-09
Identities = 142/601 (23%), Positives = 205/601 (34%), Gaps = 69/601 (11%)
Query: 167 RPQPGEGPGGPGGPPEVSRGEEGRISESPEVTRLSRGRGRPRLLTPSPTTDLHSGLQMRR 226
+P+P P P P + S+ E+ + P S+ R R R +PS T RR
Sbjct: 249 KPEPIPEPKEPS-PEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTR------PRRR 301
Query: 227 ARSPDLFTPLSRPPSPLSLPRPRSAPARRPPAPSGDTAPPARPHTPLSRIDVRPPLDWGP 286
RS SR SP P PR P+ R P PP R S + R
Sbjct: 302 HRS------RSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASL 355
Query: 287 QRQTLSRPPTPRRGPPSEAGGGKPPRSPQHWSQEPRTQAHSGSPTYLQLPPRPPGTRASM 346
+ S + R PP KPP+ ++ R + S SP + P PP T
Sbjct: 356 SGSSSSSSSSRSRSPPK-----KPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPK 410
Query: 347 VLLPGPPLESTFHQSL-------ETDTLLTKLCGQDR------LLRRLQEEIDQKQEEKE 393
P +S + T +TK G ++ + + E+ + +E+K
Sbjct: 411 TRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKG 470
Query: 394 QLEAALELTRQQLGQATREAGAPGRAWGRQRLLQDRLVSVRATLCHLTQERERVWDTYSG 453
AA + + QQ Q R+ G +D R R + S
Sbjct: 471 GKMAAAD-SVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSA 529
Query: 454 LEQELGTLRETLEYLLHLGSPQDRVSAQQQLWMVEDTLAGLGGPQKPPPHTEPDSPSPVL 513
+ET SP + +++ P PP P SP P
Sbjct: 530 SPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTP-SPPP-R 587
Query: 514 QGEESSERESLPESLELSSPRSPETDWGRPPGGDKDLASPHLGLGSP----RVSRASSPE 569
+ S R S P S P+ PP K ASP SP RVS + P+
Sbjct: 588 RRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASP-----SPPPKRRVSHSPPPK 642
Query: 570 GRHLP-----SPQLGTK-APVARPRMSAQEQLERMRRNQECGRPFPR----PTSPRLLTL 619
R P SP L +K + P S +E + P PR +SP +
Sbjct: 643 QRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRR 702
Query: 620 GRTLSPARRQ-PDVEQRPV--VGHSGAQKWLRSSGSWSSPRNTTPYLPTSEGHRERVLSL 676
G + SP RRQ P RP+ V + K ++ + S P+ + R S
Sbjct: 703 GASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAAS-----------PSPQSVRRVSSSR 751
Query: 677 SQALATEASQWHRMMTGGNLDSQGDPLPGVPLPPSDPTRQETPPPRSPPVANSGSTGFSR 736
S + + E + + SQ P P + TP P SPP NS G +
Sbjct: 752 SVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSP-SPP-RNSDQEGGGK 809
Query: 737 R 737
+
Sbjct: 810 K 810
Score = 55.5 bits (132), Expect = 2e-07
Identities = 100/379 (26%), Positives = 137/379 (36%), Gaps = 68/379 (17%)
Query: 5 RPRSSLSLASSASTISSLSSLSP-KKP----------TRAVNKIHAFGKRGNALRRDPNL 53
R RSS SL+ S+S+ SS S SP KKP TR ++ + +R +
Sbjct: 348 RRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATP 407
Query: 54 PVHIRGWLHKQDSSGLRLWKRRWFVLSGHCLFYYKDSREESVLGSVLLPSYNIRPDGPG- 112
P R Q S+ R K R V G G V + + P
Sbjct: 408 PPKTRHSPTPQQSNRTR--KSRVSVSPGR------------TSGKVTKHKGTEKRESPSP 453
Query: 113 APRGRRFTFTAEHPGMRTYVLAADTLEDLRGWLRALGRASRAEG-----DDYGQPRSPAR 167
AP+ R+ + + AAD+++ R + R ++S G +D RS +
Sbjct: 454 APKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVK 513
Query: 168 -----------PQPGEGPGGPGGPPEVSRGEEGRISESPEVTRLSRGRG------RPRLL 210
P P E S R S SP TR R R R
Sbjct: 514 NGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTP 573
Query: 211 TPSPTTDLHSGLQMRRARSPDLFTP-LSRPPSPLSLPRPRSAPARRPPAPSGDTAPPARP 269
TP P S RR+ SP ++P + R SP P+ R+A PP +PP
Sbjct: 574 TPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPP--- 630
Query: 270 HTPLSRIDVRPPLDWGPQRQTLSRPPTPRRGP---PSEAGGGKPPRSPQHWSQEPRTQAH 326
P R+ PP P+++ S P T RR P G P RS + + H
Sbjct: 631 --PKRRVSHSPP----PKQR--SSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRH 682
Query: 327 SGSPTYLQLPPRPPGTRAS 345
S SP PR P T +S
Sbjct: 683 SPSPR-----PRAPQTSSS 696
Score = 42.0 bits (97), Expect = 0.002
Identities = 93/433 (21%), Positives = 150/433 (34%), Gaps = 72/433 (16%)
Query: 362 LETDTLLTKLCGQDRLLRRLQEEIDQKQEEKEQLEAALELTRQQLGQATREAGAPGRAWG 421
L+ + + + Q++L +++ D+ + +KE+ E++ E + R++ +P
Sbjct: 126 LKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRR 185
Query: 422 RQRLLQDRLVSVRATLCHLTQERERVWDTYSGLEQELGTLRETLEYLLHLGSPQDRVS-- 479
+ ++R S + H T+ R E E L P +V
Sbjct: 186 SSPVRRERKRSHSRSPRHRTKSRSP------------SPAPEKKEKTPELPEPSVKVKEP 233
Query: 480 AQQQLWMVEDTLAGLGGPQKPPPHTEPDSPSPVLQGEESSERE-----SLPESLELSSPR 534
+ Q+ D L KP P EP PSP ++ E+E S S S R
Sbjct: 234 SVQEATSTSDILK----VPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTR 289
Query: 535 SPETDWGRPPGGDKDLASPHLGLGSPRVSRASSPE----GRHLPSP--QLGTKAPVARPR 588
S RP + + + P R SP R +P P +++PV R R
Sbjct: 290 SRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRR 349
Query: 589 MS------AQEQLERMRRNQECGRPFPRPTSPRLLT--LGRTLSPARRQ----PDVEQRP 636
S + R +P R +SP T L + SP RR+ P P
Sbjct: 350 RSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPP 409
Query: 637 VVGHSGAQKWL-------------RSSGSWSSPRNTTPYLPTSEGHRERVLSLSQA---- 679
HS + R+SG + + T S + R + LS++
Sbjct: 410 KTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDK 469
Query: 680 ----LATEASQWHRMMTGGNLDSQGDPLPGVPLPPSDPTRQETPPPRSPPVANSGSTGFS 735
A ++ Q R N S D S + ++ P RS +G G
Sbjct: 470 GGKMAAADSVQQRRQYRRQNQQSSSD-------SGSSSSSEDERPKRSH--VKNGEVGRR 520
Query: 736 RRGS-GRGGGPTP 747
RR S R P+P
Sbjct: 521 RRHSPSRSASPSP 533
Score = 42.0 bits (97), Expect = 0.002
Identities = 50/185 (27%), Positives = 71/185 (38%), Gaps = 36/185 (19%)
Query: 163 RSPARPQPGEGPGGPGGPPEVSRGEEGRISESPEVTRLSRGRGRPRLLTPSPTTDLHSGL 222
R+ + P P + P PP+ R+S SP + R P SP+
Sbjct: 613 RTASPPPPPKRRASPSPPPK------RRVSHSPP----PKQRSSPVTKRRSPSLSS---- 658
Query: 223 QMRRARSPDLFTPLSRPPSPLSLPRPRSAPARRPPAPSGDTAPPARPHTPLSRIDVRPPL 282
+ R+ SP T +R P P R +P+ RP AP ++PP VR
Sbjct: 659 KHRKGSSPSRSTREARSPQP----NKRHSPSPRPRAPQTSSSPP----------PVRRGA 704
Query: 283 DWGPQRQTLSRPPT------PRRGPPSEAGGGKPPRSPQHWSQEPRTQAHSGSP-TYLQL 335
PQR+ P T R P + P SPQ + +++ SGSP +
Sbjct: 705 SSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASP-SPQSVRRVSSSRSVSGSPEPAAKK 763
Query: 336 PPRPP 340
PP PP
Sbjct: 764 PPAPP 768
Score = 35.0 bits (79), Expect = 0.27
Identities = 44/162 (27%), Positives = 58/162 (35%), Gaps = 42/162 (25%)
Query: 162 PRSPARPQPGEGPGGP---GGPPEVSRGEEG----RISESPE---VTRLSRGRGRPRLLT 211
P+ R P P P PP V RG R S SP + R+SR T
Sbjct: 676 PQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSR--------T 727
Query: 212 PSPTTDLHSGLQMRRARSPDLFTPLSRPPSPLSLPRPRSAPARRPPAPSGDTAPPARPHT 271
P P ++++A SP P S + RS PA APP+ +
Sbjct: 728 PEPK-------KIKKAASPS-------PQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQS 773
Query: 272 PLSRIDVRPPLDWGPQRQT-LSRPPTPRRGPP---SEAGGGK 309
P +W P ++ PTP PP + GGGK
Sbjct: 774 Q------SPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGK 809
Score = 33.5 bits (75), Expect = 0.78
Identities = 44/178 (24%), Positives = 60/178 (33%), Gaps = 16/178 (8%)
Query: 152 SRAEGDDYGQPRSPARPQPGEGPGGPGGPPEVSRGEEGRISESPEVTRLSRGRGRPRLLT 211
SR++ + RSP+ +P SR R SP R R PR +
Sbjct: 280 SRSKSRSRTRSRSPSHTRPRRRHRSR------SRSYSPRRRPSPRRRPSPRRRTPPRRMP 333
Query: 212 PSPTTDLHSGLQMRRARSPDLFTPLSRPPS-------PLSLPRPRSAPARRPPAPSGDTA 264
P P RR RS + S S P P+ S+P R+ S +
Sbjct: 334 PPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSAS 393
Query: 265 PPARPHTPLSRIDVRPPLDWGPQRQTLSRPPTPRRGPPSEAGGGKPPRSPQHWSQEPR 322
PP R H P P P Q +R R+ S + G + +H E R
Sbjct: 394 PPRRRHRPSPPATPPPKTRHSPTPQQSNR---TRKSRVSVSPGRTSGKVTKHKGTEKR 448
>gi|18959210 WIRE protein [Homo sapiens]
Length = 440
Score = 59.7 bits (143), Expect = 1e-08
Identities = 68/263 (25%), Positives = 100/263 (38%), Gaps = 44/263 (16%)
Query: 136 DTLEDLRGWLRALGRASRAEGDDYGQPRSPARPQPGEGPGGPGGPPEVSRGEEGRISESP 195
D + R L L R R D +P + + P PP G +P
Sbjct: 136 DDTDSSRASLPELPRMQRPSLPDLSRPNTTSSTGMKHSSSAPPPPPP---GRRANAPPTP 192
Query: 196 EVTRLSRGRG--RPRLLTPSPTTDLHSGLQMRRARSPDLFTPLSRPPSPLSLPR------ 247
S+ R + L P+P LH G + P P+ PPSP+++
Sbjct: 193 LPMHSSKAPAYNREKPLPPTPGQRLHPGRE-----GPPAPPPVKPPPSPVNIRTGPSGQS 247
Query: 248 --PRSAPARRPP-------APSGDTAP--PARPHT-------PLSRIDVRPPLDWGPQRQ 289
P P R+PP +P+ ++AP P R ++ P+ + PP P
Sbjct: 248 LAPPPPPYRQPPGVPNGPSSPTNESAPELPQRHNSLHRKTPGPVRGLAPPPPTSASPSLL 307
Query: 290 TLSRPPTPRRGPPSEAGGGKPPRSP--QHWSQE-----PRTQAHSGSPTYLQLPPRPPG- 341
+ +RPP P R PPS G PP P ++ +++ P + H P PP PP
Sbjct: 308 S-NRPPPPARDPPSR-GAAPPPPPPVIRNGARDAPPPPPPYRMHGSEPPSRGKPPPPPSR 365
Query: 342 TRASMVLLPGPPLESTFHQSLET 364
T A P PPL + S+ T
Sbjct: 366 TPAGPPPPPPPPLRNGHRDSITT 388
Score = 53.5 bits (127), Expect = 7e-07
Identities = 61/212 (28%), Positives = 80/212 (37%), Gaps = 31/212 (14%)
Query: 165 PARPQPGEGPGGPGGPPEVSRGEEGRISES-----PEVTRLSRGRGRPRLLTPSPTTDLH 219
PA P P P + G ++S PE+ R+ R P L P+ T+
Sbjct: 111 PALQIPSSRAAAPRPPVSAASGRPQDDTDSSRASLPELPRMQRP-SLPDLSRPNTTSSTG 169
Query: 220 SGLQMRRARSPDLFTPLSRPPSPLSLPRPRSAPARR----PPAPS-----GDTAPPARPH 270
P + PP+PL + ++ R PP P G PPA P
Sbjct: 170 MKHSSSAPPPPPPGRRANAPPTPLPMHSSKAPAYNREKPLPPTPGQRLHPGREGPPAPPP 229
Query: 271 T--PLSRIDVRPPLDWGPQRQTLSRPPTPRRGPPSEAGGGKPPRSPQHWSQEPRTQAHSG 328
P S +++R GP Q+L+ PP P R PP G P SP + S Q H+
Sbjct: 230 VKPPPSPVNIRT----GPSGQSLAPPPPPYRQPPGVPNG---PSSPTNESAPELPQRHNS 282
Query: 329 SPTYLQLPPR----PPGTRASMVLL---PGPP 353
P R PP T AS LL P PP
Sbjct: 283 LHRKTPGPVRGLAPPPPTSASPSLLSNRPPPP 314
Score = 46.6 bits (109), Expect = 9e-05
Identities = 65/228 (28%), Positives = 86/228 (37%), Gaps = 34/228 (14%)
Query: 159 YGQPRSPARPQPGEGPGG-----PGGPPEVSRGEEGRISESPEVTR-------LSRGRGR 206
YG + +P+ G GG P G + S G+ + +R +S GR
Sbjct: 74 YGSGGAALQPKGGLFQGGVLKLRPVGAKDGSENLAGKPALQIPSSRAAAPRPPVSAASGR 133
Query: 207 PRLLTPSPTTDLHSGLQMRRARSPDLFTPLSRPPSPLSLPRPRSAPARRPPAPSGDT-AP 265
P+ T S L +M+R PDL SRP + S S+ A PP P AP
Sbjct: 134 PQDDTDSSRASLPELPRMQRPSLPDL----SRPNTTSSTGMKHSSSAPPPPPPGRRANAP 189
Query: 266 PARPHTPLSRIDVRPPLDWGPQRQTLSRPPTP-------RRGPPSEAGGGKPPRSPQHWS 318
P TPL + P + PPTP R GPP+ KPP SP +
Sbjct: 190 P----TPLPMHSSKAPA----YNREKPLPPTPGQRLHPGREGPPAPPPV-KPPPSPVNIR 240
Query: 319 QEPRTQAHSGSPTYLQLPPRPPGTRASMVLLPGPPLESTFHQSLETDT 366
P Q+ + P + PP P +S P L H SL T
Sbjct: 241 TGPSGQSLAPPPPPYRQPPGVPNGPSSPTNESAPELPQR-HNSLHRKT 287
Score = 35.8 bits (81), Expect = 0.16
Identities = 73/299 (24%), Positives = 95/299 (31%), Gaps = 62/299 (20%)
Query: 495 GGPQKPPPHTEPDSPSPVL-------QGEESSERESLPESLELSSPRSPETDWGRPPGGD 547
G P P + +P P + Q + S R SLPE + P P+ P
Sbjct: 109 GKPALQIPSSRAAAPRPPVSAASGRPQDDTDSSRASLPELPRMQRPSLPDLS---RPNTT 165
Query: 548 KDLASPHLGLGSPRVSRASSPEGRHLPSPQLGTKAPVA-RPRMSAQEQLERMRRNQECGR 606
H P P P +KAP R + +R+ +E G
Sbjct: 166 SSTGMKHSSSAPPPPPPGRRANAPPTPLPMHSSKAPAYNREKPLPPTPGQRLHPGRE-GP 224
Query: 607 PFPRPTSP-------RLLTLGRTLSPARRQPDVEQRPVVGHSGAQKWLRSSGSWSSPRN- 658
P P P P R G++L+P P Q P V + SSP N
Sbjct: 225 PAPPPVKPPPSPVNIRTGPSGQSLAPP--PPPYRQPPGVPNGP-----------SSPTNE 271
Query: 659 TTPYLPTSEGHRER-----VLSLSQALATEASQWHRMMTGGNLDSQGDPLPGVPLPPS-D 712
+ P LP R V L+ T AS L P PP+ D
Sbjct: 272 SAPELPQRHNSLHRKTPGPVRGLAPPPPTSASP--------------SLLSNRPPPPARD 317
Query: 713 PTRQETPPPRSPPVANSGSTG-------FSRRGS--GRGGGPTPWGPAWDAGIAPPVLP 762
P + PP PPV +G+ + GS G P P AG PP P
Sbjct: 318 PPSRGAAPPPPPPVIRNGARDAPPPPPPYRMHGSEPPSRGKPPPPPSRTPAGPPPPPPP 376
Score = 33.1 bits (74), Expect = 1.0
Identities = 55/236 (23%), Positives = 72/236 (30%), Gaps = 75/236 (31%)
Query: 493 GLGGPQKPPPHTEPDSPSPVLQGEESSERESLPESLELSSPRSPETDWGRPPGGDKDLAS 552
G GP PPP P SP + G P L+ P P + +PPG +S
Sbjct: 220 GREGPPAPPPVKPPPSPVNIRTG---------PSGQSLAPPPPP---YRQPPGVPNGPSS 267
Query: 553 PHLGLGSPRVSRASSPEGRHLPSPQLGTKAPVARPRMSAQEQLERMRRNQECGRPFPRPT 612
P +P + + + R P P G P P SA L RP P
Sbjct: 268 P-TNESAPELPQRHNSLHRKTPGPVRGLAPP---PPTSASPSL-------LSNRPPPPAR 316
Query: 613 SPRLLTLGRTLSPARRQPDVEQRPVVGHSGAQKWLRSSGSWSSPRNTTPYLPTSEGHRER 672
P P+R PV+ +G+ +P PY
Sbjct: 317 DP----------PSRGAAPPPPPPVI----------RNGARDAPPPPPPY---------- 346
Query: 673 VLSLSQALATEASQWHRMMTGGNLDSQGDPLPGVPLPPSDPTRQETPPPRSPPVAN 728
M G S+G P P P+ P PPP PP+ N
Sbjct: 347 -----------------RMHGSEPPSRGKPPPPPSRTPAGP-----PPPPPPPLRN 380
>gi|34013590 Rho GTPase activating protein 2 [Homo sapiens]
Length = 698
Score = 58.9 bits (141), Expect = 2e-08
Identities = 52/155 (33%), Positives = 70/155 (45%), Gaps = 19/155 (12%)
Query: 25 LSPK--KPTRAVNKIHAFGKRGNALRRDPNL----PVHIRGWLHKQDSSGLRLWKRRWFV 78
LSPK + RA +K G++ + R P PV GWL KQ S ++ W++RWFV
Sbjct: 2 LSPKIRQARRARSKSLVMGEQSRSPGRMPCPHRLGPVLKAGWLKKQRSI-MKNWQQRWFV 60
Query: 79 LSGHCLFYYKDSREESVLGSVLLPSYNIR--PDGPGAPRGRRFTFTAEHPGMRTYV---- 132
L G LFYYKD E G + L + P GP P F + G R V
Sbjct: 61 LRGDQLFYYKDKDEIKPQGFISLQGTQVTELPPGPEDPGKHLFEISPGGAGEREKVPANP 120
Query: 133 ----LAADTLEDLRGWLRALGRASRAE--GDDYGQ 161
L A + D+ W++A+ R A G +GQ
Sbjct: 121 EALLLMASSQRDMEDWVQAIRRVIWAPLGGGIFGQ 155
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 57.8 bits (138), Expect = 4e-08
Identities = 60/199 (30%), Positives = 84/199 (42%), Gaps = 29/199 (14%)
Query: 149 GRASRAEGDDYGQPRSPARPQPGEGPGGPGGPPEVSRGEEGRISESPEVTRLSRGRGRPR 208
G SR+ G+P+ P PQ G P GP PP +G + + P+ G+P+
Sbjct: 145 GDKSRSPRSPPGKPQGPP-PQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPP---GKPQ 200
Query: 209 LLTPSPTTDLHSGLQMRRARSPDLFTPLSRPPSPLSLPRPRSAPARRP--PAPSGDTAP- 265
P P D + R ++SP P PP + P+ P +P P P G P
Sbjct: 201 --GPPPQGD-----KSRSSQSPP-GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQ 252
Query: 266 -PARPHTPLSRIDVRPPLDWGPQRQTLSRPPTPRRGPPSEAGG---GKPPRSPQHWSQEP 321
P P P PP G + Q+ PP +GPP + G G PP + + Q+P
Sbjct: 253 GPPPPGKPQG-----PPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGN-PQQP 306
Query: 322 RTQAHSGSPTYLQLPPRPP 340
+ +G P Q PPRPP
Sbjct: 307 QAPP-AGQP---QGPPRPP 321
Score = 53.9 bits (128), Expect = 6e-07
Identities = 58/220 (26%), Positives = 84/220 (38%), Gaps = 38/220 (17%)
Query: 155 EGDDYGQPRS-PARPQ--PGEGPGGPGGPPEVSRGEEGRISESPEVTRLSRGRGRPRLLT 211
+GD PRS P +PQ P +G P GPP +G + + G+P+
Sbjct: 83 QGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQ--G 140
Query: 212 PSPTTDLHSGLQMRRARSPDLFTPLSRPPSPLSLPRPRSAPARRPPAPSGDTAPP----A 267
P P D ++RSP +P +P P P+ + P PP P PP
Sbjct: 141 PPPQGD--------KSRSPR--SPPGKPQGP--PPQGGNQPQGPPPPPGKPQGPPPQGGK 188
Query: 268 RPHTPLSRIDVRPPLDWGPQRQTLSRPPTPRRGPPSEAGG---------GKPPRSPQHWS 318
+P P + P G + ++ PP +GPP + G GKP P
Sbjct: 189 KPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 248
Query: 319 QEPRTQAHSGSPTYLQLPPRPPGTRASMVLLP-----GPP 353
+P+ G P Q PP G+++ P GPP
Sbjct: 249 NKPQGPPPPGKP---QGPPAQGGSKSQSARSPPGKPQGPP 285
Score = 53.5 bits (127), Expect = 7e-07
Identities = 53/182 (29%), Positives = 70/182 (38%), Gaps = 38/182 (20%)
Query: 160 GQPRSPARPQPGEGPGGPGGPPEVSRGEEGRISESPEVTRLSRGRGRPRLLTPSPTTDLH 219
G P+ P+ PQ G P GP PP +G + P+ G+P+ P P D
Sbjct: 34 GNPQGPS-PQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPP---GKPQ--GPPPQGD-- 85
Query: 220 SGLQMRRARSPDLFTPLSRPPSPLSLPRPRSAPARRPPAPSGDTAPPARPHTPLSRIDVR 279
++RSP PP +P+ P + P G PP +P P
Sbjct: 86 ------KSRSP------RSPPG-----KPQGPPPQGGNQPQGPPPPPGKPQGP------- 121
Query: 280 PPLDWGPQRQTLSRPPTPRRGPPSEAGGGKPPRSPQHWSQEPRTQAHSGSPTYLQLPPRP 339
PP G R PP +GPP + + PRSP Q P Q + Q PP P
Sbjct: 122 PP--QGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQP----QGPPPP 175
Query: 340 PG 341
PG
Sbjct: 176 PG 177
Score = 52.8 bits (125), Expect = 1e-06
Identities = 44/157 (28%), Positives = 62/157 (39%), Gaps = 12/157 (7%)
Query: 162 PRSPARPQPGEGPGGPGGPPEVSRGEEGRISESPEVTRLS---RGRGRPRLLTPSPTTDL 218
P+ +PQ PG P GPP +G++ R S+SP +G +P+ P P
Sbjct: 184 PQGGKKPQGPPPPGKPQGPPP--QGDKSRSSQSPPGKPQGPPPQGGNQPQ--GPPPPPGK 239
Query: 219 HSGLQMRRARSPDLFTPLSRPPSPLSLPRPRSAPARRPPAPSGDTAPPARPHTPLSRIDV 278
G + P P +P P + +S AR PP P P +
Sbjct: 240 PQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGK-----PQGPPQQEGNNPQG 294
Query: 279 RPPLDWGPQRQTLSRPPTPRRGPPSEAGGGKPPRSPQ 315
PP G +Q + P +GPP GG+P R PQ
Sbjct: 295 PPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPPQ 331
Score = 48.1 bits (113), Expect = 3e-05
Identities = 67/275 (24%), Positives = 86/275 (31%), Gaps = 41/275 (14%)
Query: 497 PQKPPPHTEPDSPSPVLQGEESSERESLPESLELSSPRSPETDWGRPPGGDKDLASPHLG 556
PQ PPP +P P P QG++S S P + P+ G PP K P G
Sbjct: 68 PQGPPPPGKPQGPPP--QGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG 125
Query: 557 LGSPRVSRASSPEGRHLPSPQLGTKAPVARPRMSAQEQLERMRRNQECGRPFPRPTSPRL 616
P + P G+ P G K+ R + NQ G P P P P+
Sbjct: 126 GNRP---QGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPP-PPPGKPQ- 180
Query: 617 LTLGRTLSPARRQPDVEQRPVVGHSGAQKWLRSSGSWSSPRNTTPYLPTSEGHRERVLSL 676
P + Q P P P P +G + R
Sbjct: 181 -------GPPPQGGKKPQGP-------------------PPPGKPQGPPPQGDKSR---- 210
Query: 677 SQALATEASQWHRMMTGGNLDSQGDPLPGVPL--PPSDPTRQETPPPRSPPVANSGSTGF 734
+ + GGN P PG P PP + + PPP P + G
Sbjct: 211 -SSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP-QGPPAQGG 268
Query: 735 SRRGSGRGGGPTPWGPAWDAGIAPPVLPQDEGAWP 769
S+ S R P GP G P P G P
Sbjct: 269 SKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNP 303
Score = 44.7 bits (104), Expect = 3e-04
Identities = 40/144 (27%), Positives = 56/144 (38%), Gaps = 11/144 (7%)
Query: 497 PQKPPPHTEPDSPSPVLQGEESSERESLPESLELSSPRSPETDWGRPPGGDKDLASPHLG 556
PQ PPP +P P P QG++S +S P + P+ G PP K P G
Sbjct: 190 PQGPPPPGKPQGPPP--QGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG 247
Query: 557 LGSPR-VSRASSPEGRHLPSPQLGTKAPVARPRMSAQEQLERMRRNQECGRPFPRPTSPR 615
P+ P+G P Q G+K+ AR + + N G P P +P+
Sbjct: 248 GNKPQGPPPPGKPQG---PPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQ 304
Query: 616 LLTLGRTLSPARRQPDVEQRPVVG 639
+ +P QP RP G
Sbjct: 305 -----QPQAPPAGQPQGPPRPPQG 323
Score = 38.5 bits (88), Expect = 0.024
Identities = 32/107 (29%), Positives = 43/107 (40%), Gaps = 14/107 (13%)
Query: 236 LSRPPSP-LSLPRPRSAPARRPPAPSGDTAPPARPHTPLSRIDVRPPLDWGPQRQTLSRP 294
+S+ SP L P+ + P G PP +P P + +P GP P
Sbjct: 23 VSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQ---GPP------P 73
Query: 295 PTPRRGPPSEAGGGKPPRSPQHWSQEPRTQAHSGSPTYLQLPPRPPG 341
P +GPP + + PRSP Q P Q + Q PP PPG
Sbjct: 74 PGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQP----QGPPPPPG 116
Score = 32.0 bits (71), Expect = 2.3
Identities = 24/73 (32%), Positives = 28/73 (38%), Gaps = 7/73 (9%)
Query: 693 GGNLDSQGDPLPGVPL--PPSDPTRQETPP----PRSPPVANSGSTGFSRRGSGRGGGPT 746
GGN P PG P PP + + PP P+ PP S R G+ GP
Sbjct: 43 GGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRS-PRSPPGKPQGPP 101
Query: 747 PWGPAWDAGIAPP 759
P G G PP
Sbjct: 102 PQGGNQPQGPPPP 114
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 57.8 bits (138), Expect = 4e-08
Identities = 94/413 (22%), Positives = 150/413 (36%), Gaps = 53/413 (12%)
Query: 150 RASRAEGDDYGQPRSPARPQPGEGPGGPGGPPEVSRGEEGRISESPEVTRLSRGRG---R 206
R R + + G P +P R +P P + R E S L + +
Sbjct: 388 RGERRKPNAGGSP-APVRRRPEASPVQKKEKKDKERENEKEKSALARERSLKKRQSLPAS 446
Query: 207 PRLLTPSPTTDLHSGLQMRRARSPDLFTPLSRPPSPLSLPRPRSAPARRPPAPSGDTAPP 266
PR + T S R SP T RP SP P P +PP+P G TA P
Sbjct: 447 PRARLSASTASELSPKSKARPSSPS--TSWHRPASPCPSPGPGHTLPPKPPSPRGTTASP 504
Query: 267 ARPHTPLSRIDVRPPLDWGPQRQTLSRPPTPRRGPPSEAGGGKPPRSPQHWSQEPRTQAH 326
G R+ +P P + K S + S P + A
Sbjct: 505 K-----------------GRVRRKEEAKESPSAAGPEDKSQSKRRASNEKESAAPASPAP 547
Query: 327 SGSPTYLQLPP---RPPG---TRASMVL---LPGPPLESTFHQSLETD-----TLLTKLC 372
S +P+ PP +PP T A+++ P PP+ + + TD LL +
Sbjct: 548 SPAPSPTPAPPQKEQPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTTDREEATRLLAEKR 607
Query: 373 GQDRLLRRLQEEIDQKQEEKEQLEAALELTRQQLGQATREAGAPGR------------AW 420
Q R R +E+ + Q E+++ +L R+ +A REA A R
Sbjct: 608 RQAREQREREEQERRLQAERDKRMREEQLAREAEARAEREAEARRREEQEAREKAQAEQE 667
Query: 421 GRQRLLQDRLVSVRATLCHLTQERERVWDTYSGLEQELGTLRETLEYLLHLGSPQDRVSA 480
++RL + + + + ++R + EQE R+ LE ++ + R S
Sbjct: 668 EQERLQKQKEEAEARSREEAERQRLEREKHFQQQEQERQERRKRLEEIM----KRTRKSE 723
Query: 481 QQQLWMVEDTLAGLGGPQKPPPHTEPDSPSPVLQGEESSERESLPESLELSSP 533
+ +D+ P P ++ SP LQ E + E +P+ + S P
Sbjct: 724 VSETKQKQDSKEANANGSSPEPVKAVEARSPGLQKEAVQKEEPIPQEPQWSLP 776
Score = 38.5 bits (88), Expect = 0.024
Identities = 132/594 (22%), Positives = 196/594 (32%), Gaps = 121/594 (20%)
Query: 239 PPSPLSLPRPRSAPARRPPAPSG-------DTAPPARPHTPLSRIDVRPPLDWGPQRQTL 291
PP P P P P+ PP S DT P + T ++ + P P Q
Sbjct: 22 PPEPR--PSPEGDPSPPPPPMSALVPDTPPDTPPAMKNATSSKQLPLEPE---SPSGQVG 76
Query: 292 SRPPTPRRGPPSEAGGGKPPRSPQHWSQEPRTQAHSGSPTYLQLPPRPPGTRASMVLLPG 351
RP P+ PS + P P ++ R S P+ +P
Sbjct: 77 PRPAPPQEESPSSEAKSRGPTPPAMGPRDARPPRRSSQPSPTAVPAS-----------DS 125
Query: 352 PPLESTFHQSLETDTLLTKLCGQDRLLRRLQEEIDQKQEEKEQLEA--ALELTRQQLGQA 409
PP + K G+ L + ++++E + L A A+ L +++ +A
Sbjct: 126 PPTKQE-----------VKKAGERHKLAK-----ERREERAKYLAAKKAVWLEKEEKAKA 169
Query: 410 TREAGAPGRAWGRQRLLQDRLVSV--RATLCHLTQERERVWDTYSGLEQELGTLRETLEY 467
RE R R+RL + RL + RA L +ER+R Q+L +E E
Sbjct: 170 LREKQLQER---RRRLEEQRLKAEQRRAAL----EERQR---------QKLEKNKERYEA 213
Query: 468 LLHLGSPQDRVSAQQQLWMVEDTLAGLGGPQKP------------PPHTEP--------- 506
+ + +QQ W L K P H +
Sbjct: 214 AIQRSVKKTWAEIRQQRWSWAGALHHSSPGHKTSGSRCSVSAVNLPKHVDSIINKRLSKS 273
Query: 507 -----DSPSP----VLQGEESS--ERESLPESLELSSPRSPET--DWGRPPGGDKDLA-S 552
+SPS L ESS +R P L+ RS T GR G D
Sbjct: 274 SATLWNSPSRNRSLQLSAWESSIVDRLMTPTLSFLARSRSAVTLPRNGRDQGRGCDPGRG 333
Query: 553 PHLGLGSPRVSRASSPEGRHLPSPQLGTKAPVARPRMSAQEQLE--RMRRNQECGRPFPR 610
P G ++R P+ H PS PV PR ++ L + R+ P
Sbjct: 334 PTWGRAGASLARGPQPDRTH-PS----AAVPVC-PRSASASPLTPCSVTRSVHRCAPAGE 387
Query: 611 PTSPRLLTLGRTLSPARRQPDV------EQRPVVGHSGAQKWLRSSGSWSSPRNTTPYLP 664
R G + +P RR+P+ E++ + +K + R + P P
Sbjct: 388 RGERRKPNAGGSPAPVRRRPEASPVQKKEKKDKERENEKEKSALARERSLKKRQSLPASP 447
Query: 665 TSEGHRERVLSLSQAL----ATEASQWHRMMTGGNLDSQGDPLPGVPLPPSDPT------ 714
+ LS ++ ++ WHR + G LP P P T
Sbjct: 448 RARLSASTASELSPKSKARPSSPSTSWHRPASPCPSPGPGHTLPPKPPSPRGTTASPKGR 507
Query: 715 -RQETPPPRSPPVANSGSTGFS-RRGSGRGGGPTPWGPAWDAGIAP-PVLPQDE 765
R++ SP A S RR S P PA +P P PQ E
Sbjct: 508 VRRKEEAKESPSAAGPEDKSQSKRRASNEKESAAPASPAPSPAPSPTPAPPQKE 561
>gi|19924099 synapsin I isoform Ia [Homo sapiens]
Length = 705
Score = 55.8 bits (133), Expect = 1e-07
Identities = 69/239 (28%), Positives = 91/239 (38%), Gaps = 34/239 (14%)
Query: 162 PRSPARPQPGEGPGGPG------GPPEVSR----GEE-----GRISESPEVTRLSRGRGR 206
P + RP P GP PG GPP R G++ G + SP RL
Sbjct: 455 PPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSA 514
Query: 207 PR--LLTPSPTTDLHSGLQMRRARSPDLFTPLSRPPSPLSLPRPRSAP-ARRPPAPSGDT 263
P+ +P T G Q R P +RPP+ S R P A R + SG
Sbjct: 515 PQQPASQAAPPTQ-GQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPA 573
Query: 264 APPARPHTPLSRI----DVRPPLDWGPQRQTLSRPPTPRRGPPS--------EAGGGKP- 310
P A P + +PP GP RQ P PR GPP+ G+P
Sbjct: 574 PPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPK 633
Query: 311 PRSPQHWSQE--PRTQAHSGSPTYLQLPPRPPGTRASMVLLPGPPLESTFHQSLETDTL 367
P+ Q SQ+ P A +G P + QL T A + P PP S ++ +T+
Sbjct: 634 PQLAQKPSQDVPPPATAAAGGPPHPQLNKSQSLTNAFNLPEPAPPRPSLSQDEVKAETI 692
Score = 38.9 bits (89), Expect = 0.018
Identities = 68/260 (26%), Positives = 82/260 (31%), Gaps = 82/260 (31%)
Query: 492 AGLGGPQKPPPHTEPDSPSPVLQGEESSERESLPESLELSSPRSPETDWGRPPGGDKDLA 551
AG Q+PPP P P P Q + P PP G + L+
Sbjct: 453 AGPPAQQRPPPQGGPPQPGPGPQRQ------------------GPPLQQRPPPQGQQHLS 494
Query: 552 SPHLGLGSPRVSRASSPEGRHLPSPQLGTKAPVARPRMSAQEQLERMRRNQECGRPFPRP 611
GLG P A SP + LPSP + P ++ Q Q GR
Sbjct: 495 ----GLGPP----AGSPLPQRLPSPTSAPQQPASQAAPPTQGQ----------GR----- 531
Query: 612 TSPRLLTLGRTLSPARRQPDVEQRPVVGHSGAQKWLRSSGSWSSPRNTTPYLPTSEGHRE 671
+ RPV G GA R S S R P T
Sbjct: 532 ---------------------QSRPVAGGPGAPPAARPPASPSPQRQAGPPQAT------ 564
Query: 672 RVLSLSQALATEASQWHRMMTGGNLDSQGDPLPGVPLPPSDPTRQET---PPPRS-PPVA 727
R S+S +AS G QG P P P+ PTRQ + P PR+ PP
Sbjct: 565 RQTSVSGPAPPKASG----APPGGQQRQGPPQK--PPGPAGPTRQASQAGPVPRTGPPTT 618
Query: 728 NSGSTGFSRRGSGRGGGPTP 747
G G G P P
Sbjct: 619 QQPRPS----GPGPAGRPKP 634
Score = 38.9 bits (89), Expect = 0.018
Identities = 43/159 (27%), Positives = 59/159 (37%), Gaps = 25/159 (15%)
Query: 495 GGPQKPPPHTEPDSPSPVLQ-GEESSERESLPESLELSSPRSPETDWGRPPGGDKDLASP 553
GGP PP P SPSP Q G + R++ +S P P+ G PPGG + P
Sbjct: 538 GGPGAPPAARPPASPSPQRQAGPPQATRQT-----SVSGPAPPKAS-GAPPGGQQRQGPP 591
Query: 554 HLGLGSPRVSRASSPEGRHLPSPQLGT----------KAPVARPR----MSAQEQLERMR 599
G +R +S G P P+ G P RP+ + +
Sbjct: 592 QKPPGPAGPTRQASQAG---PVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPA 648
Query: 600 RNQECGRPFPRPTSPRLLTLGRTL-SPARRQPDVEQRPV 637
G P P+ + LT L PA +P + Q V
Sbjct: 649 TAAAGGPPHPQLNKSQSLTNAFNLPEPAPPRPSLSQDEV 687
Score = 33.5 bits (75), Expect = 0.78
Identities = 18/63 (28%), Positives = 22/63 (34%)
Query: 703 LPGVPLPPSDPTRQETPPPRSPPVANSGSTGFSRRGSGRGGGPTPWGPAWDAGIAPPVLP 762
L G+ P P Q P P S P + +G GR P GP PP P
Sbjct: 493 LSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASP 552
Query: 763 QDE 765
+
Sbjct: 553 SPQ 555
Score = 30.4 bits (67), Expect = 6.6
Identities = 54/203 (26%), Positives = 67/203 (33%), Gaps = 25/203 (12%)
Query: 565 ASSPEGRHLPSPQLGTKAPVARPRMSAQEQLERMRRNQECGRPFPRPTSPRLLTLGRTLS 624
AS G H +P +P A P L R Q G P + P+
Sbjct: 426 ASPGRGSHGQTP-----SPGALP-------LGRQTSQQPAGPPAQQRPPPQGGPPQPGPG 473
Query: 625 PARRQPDVEQRPVVGHSGAQKWLRSSGSWSSPRNTTPYLPTSEGHRERVLSLSQALATEA 684
P R+ P ++QRP G Q SP PTS + SQA
Sbjct: 474 PQRQGPPLQQRPPP--QGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPA----SQAAPPTQ 527
Query: 685 SQWH--RMMTGGNLDSQGDPLPGVPLP-----PSDPTRQETPPPRSPPVANSGSTGFSRR 737
Q R + GG P P P P TRQ + +PP A+ G +R
Sbjct: 528 GQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQR 587
Query: 738 GSGRGGGPTPWGPAWDAGIAPPV 760
P P GP A A PV
Sbjct: 588 QGPPQKPPGPAGPTRQASQAGPV 610
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 55.5 bits (132), Expect = 2e-07
Identities = 163/656 (24%), Positives = 221/656 (33%), Gaps = 120/656 (18%)
Query: 147 ALGRASRAEGDDYGQPRSP--ARPQPG-EGPGGPGGPPEVSRGEEGRISE-SPEVTRL-S 201
A+ R SRA G + G PR ARP+P EGP VS E +E SP R S
Sbjct: 175 AMARRSRAAGTEVGLPRPAPSARPRPPTEGPR-----KSVSSASEHSTTEPSPAARRRPS 229
Query: 202 RGRGRPRLLTPSPTTDLHSGLQMRRARSPDLFTPLSRPPSPLSLPRPRSAPARRPP---A 258
G G R + S ++ R+ TP R P+ S P+P+ A RPP
Sbjct: 230 AGGGLQRPASRSLSSSATPLSSPARSGPSARGTP--RAPAHPSQPKPKGLQALRPPQVTP 287
Query: 259 PSGDTAPPARPHTPLSRIDVRPPLDWGPQRQTLSRPPTPRRGPPSEAGGGKP---PRSPQ 315
P D AP PLS + P G + + P P PP A P P SP
Sbjct: 288 PRKDAAPAL---GPLSSSPLATPSPSGTKAR-----PVP---PPDNAATPLPATLPPSPP 336
Query: 316 HWSQEPRTQAHSGSPTYLQLPPRPPGTRASMV--LLPGPPLESTFHQSLETDTLLTKLCG 373
+ P +P LQ P PP T S + PP+++ SL+T
Sbjct: 337 LATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAP--PSLQT--------- 385
Query: 374 QDRLLRRLQEEIDQKQEEKEQLEAALELTRQQLGQATREAGAPGRAWGRQRLLQDRLVSV 433
+ +Q + + L L+ QAT G+P ++
Sbjct: 386 ----IPPIQVPHSLTSPSLQAPPSPLALSSL---QATTSLGSP---------------TL 423
Query: 434 RATLCHLTQERERVWDTYSGLEQELGTLRETLEYLLHLGSPQDRVSAQQQLWMVEDTLAG 493
+AT LT + + + + T P D Q A
Sbjct: 424 QATHSFLTMSPRQTQASLTSPSRPAST-------------PPDSPPLQ----------AP 460
Query: 494 LGGPQKPPPHTEPDSPSPVLQGEESSERESLPESLELSSPRSPETDWGRPP-GGDKDLAS 552
L P PP T L + SL SP++P + PP LA
Sbjct: 461 LSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAP 520
Query: 553 PHLGLGSPRVSRASSPEGRHLPS---PQLGT-KAPVARPRMSAQEQLERMRRNQECGRPF 608
P L +P S ++P +LPS P L T AP+ P + C P
Sbjct: 521 P--SLQTPPAS-LTTPPLENLPSLAPPPLQTASAPLTTPHL----------ETPPCPAPC 567
Query: 609 PRPTSPRLLTLGRTLSPARRQPDVEQRPVVGHSGAQKWLRS---SGSWSSPRNTTPYL-- 663
P P LT +P+ Q P S + L S S + P P L
Sbjct: 568 PLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLAL 627
Query: 664 -PTSEGHRERVLSLSQALATEASQWHRMMTGGNLDSQGDPLPGVPLPPSDPTRQETPPPR 722
P LAT + Q + L + P PPS P + PP
Sbjct: 628 PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSP------PPSPPVQAPFSPPA 681
Query: 723 SPPVANSGSTGFSRRGSGRGGGP--TPWGPAWDAGIAPPVLPQDEGAWPLRVTLLQ 776
SPPV+ S +T S+ P P P ++P P + PL LQ
Sbjct: 682 SPPVSPS-ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQ 736
Score = 50.8 bits (120), Expect = 5e-06
Identities = 44/154 (28%), Positives = 59/154 (38%), Gaps = 21/154 (13%)
Query: 209 LLTPSPTTDLHSGLQMRRAR-----SPDLFTPLSRPPSPLSLPRPRSAPARRPPAPSGDT 263
L TPSP + + +A SP + P S P SP P + P++ PP+ +
Sbjct: 645 LATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSA-TPPSQAPPSLAAPP 703
Query: 264 --APPARPHTPLSRIDVRPPLDWGPQRQT--LSRPPTPRRGPPSEAGGGKPPRSPQHWSQ 319
PP+ P +P PP P L PP+P PP PPR P +
Sbjct: 704 LQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAA 763
Query: 320 EPRTQAHSGSPTYLQLPPRPPGTRASMVLLPGPP 353
P LQ+PP PP + L PP
Sbjct: 764 PP-----------LQVPPSPPASLPMSPLAKPPP 786
Score = 50.1 bits (118), Expect = 8e-06
Identities = 58/205 (28%), Positives = 73/205 (35%), Gaps = 34/205 (16%)
Query: 162 PRSPARPQPGEGPGGPGGPPEVSRGEEGRISESPEVTRLSRGRGRPRLLTPSPTTDLHSG 221
P SP P E P PP + SP + L P L TP P
Sbjct: 572 PPSPLTTPPPETPSSIATPPP----QAPPALASPPLQGLPSPPLSP-LATPPPQAPPXLA 626
Query: 222 LQMRRAR-SPDLFTPLSRPPSPLSLPRPRS----------APARRPPAPSGDTAPPARPH 270
L +A SP P S P SPL+ P P++ AP PP+P AP + P
Sbjct: 627 LPPLQAPPSP----PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ-APFSPPA 681
Query: 271 TPLSRIDVRPPLDWGPQ--RQTLSRPPTPRRGPPSEAGGGKPPRSPQHWSQEPRTQAHSG 328
+P PP P L PP+P PP PP++P + P
Sbjct: 682 SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPP------- 734
Query: 329 SPTYLQLPPRPPGTRASMVLLPGPP 353
LQ+PP PP + PP
Sbjct: 735 ----LQVPPSPPASPPMSPSATPPP 755
Score = 50.1 bits (118), Expect = 8e-06
Identities = 66/213 (30%), Positives = 82/213 (38%), Gaps = 36/213 (16%)
Query: 162 PRSPARPQPGEGPGGPGGPP-EVSRGEEGRISESPEVTRLSRG----RGRPRLLTPSP-T 215
P SP+ P + P PP +V SP T + P + PSP
Sbjct: 684 PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPA 743
Query: 216 TDLHSGLQMRRARSPDLFT--PLSRPPSP-LSLPRPRSAPARRPPAPSGDTAPPARPHTP 272
+ S R P L PL PPSP SLP +P +PP APPA P
Sbjct: 744 SPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPM---SPLAKPPPQ----APPALATPP 796
Query: 273 LSRIDVRPPLDW---GPQRQTLSRPPTPRRGPPSEAGGGKPPRSPQHWSQEPRTQAHSGS 329
L + PP + P + S P +P PP +A PP Q P + S
Sbjct: 797 LQALP-SPPASFPGQAPFSPSASLPMSPLATPPPQA----PPVLAAPLLQVPPSPP--AS 849
Query: 330 PTYLQLPPRPP---------GTRASMVLLPGPP 353
PT LQ P RPP G R ++ L PGPP
Sbjct: 850 PT-LQAPRRPPTPGPDTSVSGPRLTLALAPGPP 881
Score = 47.4 bits (111), Expect = 5e-05
Identities = 60/200 (30%), Positives = 71/200 (35%), Gaps = 39/200 (19%)
Query: 162 PRSPARPQPGEGPGGPGGPP-EVSRGEEGRISESPEVTRLSRG----RGRPRLLTPSPTT 216
P SP+ P + P PP +V SP T R P + PSP
Sbjct: 715 PMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPA 774
Query: 217 DLH-SGLQMRRARSPDLFT--PLSRPPSPLSLPRPRSAPARRPPAPSGD-------TAPP 266
L S L ++P PL PSP P S P + P +PS T PP
Sbjct: 775 SLPMSPLAKPPPQAPPALATPPLQALPSP-----PASFPGQAPFSPSASLPMSPLATPPP 829
Query: 267 ARPHT---PLSRIDVRPPLDWGPQRQTLSRPPTPRRGPPSEAGG---------GKPP--- 311
P PL ++ PP P Q RPPTP GP + G G PP
Sbjct: 830 QAPPVLAAPLLQVPPSPPAS--PTLQAPRRPPTP--GPDTSVSGPRLTLALAPGPPPPPS 885
Query: 312 RSPQHWSQEPRTQAHSGSPT 331
RSP P HS S T
Sbjct: 886 RSPSSTLSGPDLAGHSSSAT 905
Score = 45.4 bits (106), Expect = 2e-04
Identities = 69/244 (28%), Positives = 88/244 (36%), Gaps = 37/244 (15%)
Query: 130 TYVLAADTLEDLRGWLRALGRASRAEGDDYGQPRS-PARPQPGEGPGG-PGGPPEVSRGE 187
T L + TL+ +L R ++A +P S P P + P P PP
Sbjct: 415 TTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPL----- 469
Query: 188 EGRISESPEVTRLSRG------RGRPRLLTPSPTTDLHSGLQMRRARSPDLFTP-LSRPP 240
+ S SP V+ LS + L + SP L S + L P L PP
Sbjct: 470 --QTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPP 527
Query: 241 SPLSLPRPRSAPARRPPAPSGDTAPPARPHTPLSRIDVRPPLDWGPQRQTLSRPPTPR-- 298
+ L+ P + P+ PP +AP PH PL P T P TP
Sbjct: 528 ASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSI 587
Query: 299 -----RGPPSEA-----GGGKPPRSPQHWSQEPRTQAHSGSPTYLQLPP--RPPGTRASM 346
+ PP+ A G PP SP P QA P L LPP PP AS
Sbjct: 588 ATPPPQAPPALASPPLQGLPSPPLSP---LATPPPQA----PPXLALPPLQAPPSPPASP 640
Query: 347 VLLP 350
L P
Sbjct: 641 PLSP 644
Score = 45.1 bits (105), Expect = 3e-04
Identities = 51/197 (25%), Positives = 65/197 (32%), Gaps = 37/197 (18%)
Query: 162 PRSPARPQPGEGPGGPGGPPEVSRGEEGRISESPEVTRLSRGRGRPRLLTPSPTTDLHSG 221
P SP P + P P P VS P + P + PSP
Sbjct: 664 PFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLA------APPLQVPPSP------- 710
Query: 222 LQMRRARSPDLFTPLSRPPSPLSLPRPRSAPARRPPA----PSGDTAPPARPH-TPLSRI 276
P S P SP + P P++ P P PS +PP P TP R+
Sbjct: 711 -------------PASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRV 757
Query: 277 DVRPPLDWGPQRQTLSRPPTPRRGPPSEAGGGKPPRSPQHWSQEPRTQAHSGSPTYLQLP 336
PPL P Q PP+P P PP++P + P S ++
Sbjct: 758 ---PPLLAAPPLQV---PPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQA 811
Query: 337 PRPPGTRASMVLLPGPP 353
P P M L PP
Sbjct: 812 PFSPSASLPMSPLATPP 828
Score = 37.4 bits (85), Expect = 0.054
Identities = 72/266 (27%), Positives = 89/266 (33%), Gaps = 57/266 (21%)
Query: 500 PPPHTEPDSPSPVLQGEESSERESLPESLELSSPRSPETDWGRPPGGDKDLASPHL-GLG 558
PPP P +P LQ S P SL +S P PP LA+P L L
Sbjct: 753 PPPRVPPLLAAPPLQVPPSP-----PASLPMSPLAKP------PPQAPPALATPPLQALP 801
Query: 559 SPRVS---RASSPEGRHLPSPQLGTKAPVARPRMSAQEQLERMRRNQECGRPFPRPTSPR 615
SP S +A LP L T P A P ++A L ++ P P SP
Sbjct: 802 SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAP--LLQV--------PPSPPASP- 850
Query: 616 LLTLGRTLSPARRQPDVEQRPVVGHSGAQKWLRSSGSWSSPRNTTPYL----PTSEGHRE 671
TL RR P P SG + L + P + +P P GH
Sbjct: 851 ------TLQAPRRPPT--PGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSS 902
Query: 672 RVLSLSQALATEASQWHRMMTGGNLDSQGDPLPGVPLPPSDPTRQETPPPRSPPVANSGS 731
S + L S G + P P L P P +PP+A G+
Sbjct: 903 SATSTPEELRGYDS-------GPEGGAAASPPPDAELAACHPAAWSRGP--APPLAFRGA 953
Query: 732 TGFSRRGSGRGGGPTPWGPAWDAGIA 757
G P PW PA G A
Sbjct: 954 PG----------APLPWPPATGPGSA 969
Score = 33.9 bits (76), Expect = 0.59
Identities = 50/217 (23%), Positives = 71/217 (32%), Gaps = 36/217 (16%)
Query: 559 SPRVSRASSPEGRHLPSPQLGTKAPVARPRMSAQEQLERMRRNQECGRPFPRPTSPRLLT 618
+P+ S S+ R P GT +P R A + R RP P PR
Sbjct: 150 APKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPR--- 206
Query: 619 LGRTLSPARRQPDVEQRPVVGHSGAQKWLRSSGSWSSPRNTTPYLPTSEGHRERVLSLSQ 678
+++S A E P P++ G +R S+
Sbjct: 207 --KSVSSASEHSTTEPSPAARRR----------------------PSAGGGLQR--PASR 240
Query: 679 ALATEASQWHRMMTGGNLDSQGDP-LPGVPLPPSDPTRQETPPPRSPPVANSGSTGFSRR 737
+L++ A+ G ++G P P P P Q PP+ P +
Sbjct: 241 SLSSSATPLSSPARSGP-SARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPL 299
Query: 738 GSGRGGGPTPWGPAWDAGIAPPVLPQDEGAWPLRVTL 774
S P+P G A PV P D A PL TL
Sbjct: 300 SSSPLATPSPSGTK-----ARPVPPPDNAATPLPATL 331
>gi|237757326 synaptojanin 1 isoform d [Homo sapiens]
Length = 1526
Score = 55.1 bits (131), Expect = 2e-07
Identities = 50/141 (35%), Positives = 67/141 (47%), Gaps = 17/141 (12%)
Query: 207 PRLLTPSPTTDLHSGLQMRRARSPDLFTPLSRPPSPLSLP-RPRSAPARRPPAPSGDTAP 265
P+ L PS ++ L + SP +S P P SLP RP AP+R P PS ++P
Sbjct: 1022 PQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVP-SLPIRPSRAPSRTPGPPSAQSSP 1080
Query: 266 -PARPHTPLSRIDVRPPLDWGPQRQTLSRP------PTPRRGPPSEAGGGKPPRSPQHWS 318
A+P TPL + D PL+ P+R RP P P + PP +G +P SPQ
Sbjct: 1081 IDAQPATPLPQKDPAQPLE--PKRPPPPRPVAPPTRPAPPQRPPPPSGRSQP--SPQAGL 1136
Query: 319 QEPRTQAHS-GSPTYLQLPPR 338
P +S PT +PPR
Sbjct: 1137 AGPGPAGYSTARPT---IPPR 1154
Score = 47.4 bits (111), Expect = 5e-05
Identities = 69/241 (28%), Positives = 83/241 (34%), Gaps = 48/241 (19%)
Query: 157 DDYG---QPRSPARPQPGEGPG---GPGGPPEVSRGEEGRISESPEVTRLSRGRGRPRLL 210
DDY + P QP G P P S + ISE P V L R
Sbjct: 1011 DDYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGP-VPSLPIRPSRAPSR 1069
Query: 211 TPSPTTDLHSGLQMRRAR---SPDLFTPLS--RPPSPLSLPRP-RSAPARRPPAPSGDTA 264
TP P + S + + A D PL RPP P + P R AP +RPP PSG +
Sbjct: 1070 TPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQ 1129
Query: 265 P----------PARPHTPLSRIDVRPPLDWGPQ---RQTLSRPPTPRRGPPSEAGGGK-- 309
P PA T I R + PQ R + R + SE G
Sbjct: 1130 PSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTF 1189
Query: 310 -----------PPRS----PQHWSQEPRTQA-----HSGSPTYLQLPPRPPGTRASMVLL 349
PP+S P QEP SG L+ PP+PP S L
Sbjct: 1190 LPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSL 1249
Query: 350 P 350
P
Sbjct: 1250 P 1250
Score = 35.0 bits (79), Expect = 0.27
Identities = 61/236 (25%), Positives = 86/236 (36%), Gaps = 19/236 (8%)
Query: 501 PPHTEPDSPSPVLQGEESSERESLPESLELSSPRSPETDWGRPPGGDKDLASPHLGLGSP 560
P H +P S S + SS R S +S +S P RP P SP
Sbjct: 1022 PQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPI-RPSRAPSRTPGPPSAQSSP 1080
Query: 561 RVSRASSPEGRHLPSPQLGTKAP-----VARPRMSAQEQLERMRRNQECGRPFPRPTSPR 615
++ ++P + P+ L K P VA P A Q R GR P P +
Sbjct: 1081 IDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQ----RPPPPSGRSQPSPQAGL 1136
Query: 616 LLTLGRTLSPARRQPDVEQRPVVGHSGAQKWLRSSGSWSSPRNTTPYLPTSEGHRERVLS 675
S AR P + R V S Q R+S +P + + TS+G
Sbjct: 1137 AGPGPAGYSTAR--PTIPPRAGV-ISAPQSHARASAGRLTPESQSKTSETSKGST----F 1189
Query: 676 LSQALATEASQWHRMMTGGNLDSQGDPLPGV--PLPPSDPTRQETPPPRSPPVANS 729
L + L +A+ + +PL V P+P S P PP+ PP + S
Sbjct: 1190 LPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRS 1245
Score = 35.0 bits (79), Expect = 0.27
Identities = 47/202 (23%), Positives = 73/202 (36%), Gaps = 26/202 (12%)
Query: 498 QKPPPHTEPDSPSPVLQGEESSERESLPESLELSSPRSPETDWGRPPGGDKDLASPHLGL 557
Q P +P +P P + E + P ++ P P PP + SP GL
Sbjct: 1077 QSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQAGL 1136
Query: 558 GSPRVSRASS------PEGRHLPSPQLGTKAPVARPRMSAQEQLERMRRNQECGRPFPRP 611
P + S+ P + +PQ +A R +Q + + P P
Sbjct: 1137 AGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTF---LPEP 1193
Query: 612 TSPRLLTLGRTL--SPARR--QPDVEQRPVVGHSGAQKWL----------RSSGSWSSPR 657
P+ ++ PA+R +P V + SG Q L RSS S S
Sbjct: 1194 LKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEA 1253
Query: 658 NTTPYLPT---SEGHRERVLSL 676
++ P + T S+G RE L +
Sbjct: 1254 SSQPQVKTNGISDGKRESPLKI 1275
>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
Length = 1094
Score = 55.1 bits (131), Expect = 2e-07
Identities = 63/234 (26%), Positives = 79/234 (33%), Gaps = 41/234 (17%)
Query: 149 GRASRAEGDDYGQPRSPAR-------PQPGEGPGGPGGPPEVSRGEEGRISESPEVTRLS 201
G ++G GQP S PQ G G G P G + I S +++
Sbjct: 429 GSTLSSKGGSEGQPESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLS--G 486
Query: 202 RGRGRPRLLTPSPTTDLHSGLQMRRARSPDLFTPLSRPPSPL-----SLPRPRS------ 250
R +L P P L R PD PL PP P LPRP +
Sbjct: 487 RSVSLRKLKRPPPPPRRTHSLHQRGLAVPD--GPLGLPPKPERKQQPQLPRPPTTGGSEG 544
Query: 251 ---APARRPPA--------PSGDTAPPARPHTPLSRIDVRPPLDWGPQRQTLSRPPTPRR 299
AP PA P G PP P LS P + Q T + PP
Sbjct: 545 AGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLS-----PSSGYSSQSGTPTLPPKGLA 599
Query: 300 GPPSEAGGGKPPRSPQHWSQEPRTQAHSGSPTYL---QLPPRPPGTRASMVLLP 350
GPP+ G +PP+ + S + S S T L P P +L P
Sbjct: 600 GPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTP 653
Score = 38.1 bits (87), Expect = 0.032
Identities = 58/212 (27%), Positives = 71/212 (33%), Gaps = 44/212 (20%)
Query: 156 GDDYGQPRSPARPQPGEGPGG------PGGP----PEVSRGEEGRISESPEVTRLSRGRG 205
GD + P P P P P P P P V G SP+
Sbjct: 655 GDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSP------- 707
Query: 206 RPRLLTPSPTTDLHSGLQMRRARSPDLFTPLSRPPSPLSLPRPRSAPARRPPAPSGDTAP 265
P+P T L + LQ SP + S PPSP P P ++P +
Sbjct: 708 ------PTPQTTL-TPLQ----ESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSA 756
Query: 266 PARPHTPLSRIDVRPPLDWGPQRQTLSRPPTPRRGPPSEAGGGKPPRSPQHWSQEPR--- 322
PL + PP P+ Q LS P PP EA P S P
Sbjct: 757 SETAEEPLQDPNWPPPPPPAPEEQDLSMADFP---PPEEAFFSVASPEPAGPSGSPELVS 813
Query: 323 -TQAHSGSPTYLQLPPRPPGTRASMVLLPGPP 353
A S S T LQ+ +PPG+ P PP
Sbjct: 814 SPAASSSSATALQI--QPPGS-------PDPP 836
Score = 34.3 bits (77), Expect = 0.46
Identities = 29/100 (29%), Positives = 39/100 (39%), Gaps = 5/100 (5%)
Query: 493 GLGGPQKPPPHTEPDSPSPV--LQGEESSERESLPESLELSSPRSPETDWGRP---PGGD 547
GL GP P +P P V L+ +S SL SS +P G P GD
Sbjct: 597 GLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGD 656
Query: 548 KDLASPHLGLGSPRVSRASSPEGRHLPSPQLGTKAPVARP 587
+ + PH + +P S P + +P L A V P
Sbjct: 657 RFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGP 696
Score = 33.9 bits (76), Expect = 0.59
Identities = 39/133 (29%), Positives = 50/133 (37%), Gaps = 23/133 (17%)
Query: 177 PGGPPEVSRGEEGRISESPEVTR---LSRGRGRPRLLTP-SPTT--DLHSGLQMRRARSP 230
P GPPE E R +SP T S+G + +L P SP T DL L
Sbjct: 952 PNGPPEA----EPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSIS 1007
Query: 231 DLFTPLSRPPSPLSLPRPRSAPARRPPA---PSGDTAPPARPHTPLSRIDVRPPLDWGPQ 287
+ RPP P+ +P PP PS PPA P P + PP + P
Sbjct: 1008 E-----QRPPQA-----PKKSPKAPPPVARKPSVGVPPPASPSYPRAEPLTAPPTNGLPH 1057
Query: 288 RQTLSRPPTPRRG 300
Q ++ G
Sbjct: 1058 TQDRTKRELAENG 1070
>gi|237757312 synaptojanin 1 isoform c [Homo sapiens]
Length = 1295
Score = 54.7 bits (130), Expect = 3e-07
Identities = 49/140 (35%), Positives = 66/140 (47%), Gaps = 20/140 (14%)
Query: 207 PRLLTPSPTTDLHSGLQMRRARSPDLFTPLSRPPSPLSLP-RPRSAPARRPPAPSGDTAP 265
P+ L PS ++ L + SP +S P P SLP RP AP+R P PS ++P
Sbjct: 1027 PQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVP-SLPIRPSRAPSRTPGPPSAQSSP 1085
Query: 266 -PARPHTPLSRIDVRPPLDWGPQRQTLSRPPTPRR-GPPSEAGGGKPPRSPQHWSQEPRT 323
A+P TPL + D PL+ RPP PR PP+ PP+ P P +
Sbjct: 1086 IDAQPATPLPQKDPAQPLE-------PKRPPPPRPVAPPTRPA---PPQRP-----PPPS 1130
Query: 324 QAHSGSPTYLQL-PPRPPGT 342
A S +PT + P+ PGT
Sbjct: 1131 GARSPAPTRKEFGAPKSPGT 1150
Score = 40.8 bits (94), Expect = 0.005
Identities = 72/267 (26%), Positives = 87/267 (32%), Gaps = 74/267 (27%)
Query: 157 DDYG---QPRSPARPQPGEGPG---GPGGPPEVSRGEEGRISESPEVTRLSRGRGRPRLL 210
DDY + P QP G P P S + ISE P V L R
Sbjct: 1016 DDYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGP-VPSLPIRPSRAPSR 1074
Query: 211 TPSPTTDLHSGLQMRRAR---SPDLFTPLS--RPPSPLSLPRP-RSAPARRPPAPSGDTA 264
TP P + S + + A D PL RPP P + P R AP +RPP PSG +
Sbjct: 1075 TPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARS 1134
Query: 265 P-PAR-----PHTP-------LSRIDVRPPLDW---GPQRQTLSRPPTPRRG-------- 300
P P R P +P + R P GP + +RP P R
Sbjct: 1135 PAPTRKEFGAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQS 1194
Query: 301 ---------------PPSEAGGGK-------------PPRS----PQHWSQEPRTQA--- 325
SE G PP+S P QEP
Sbjct: 1195 HARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAP 1254
Query: 326 --HSGSPTYLQLPPRPPGTRASMVLLP 350
SG L+ PP+PP S LP
Sbjct: 1255 MPQSGPQPNLETPPQPPPRSRSSHSLP 1281
Score = 33.9 bits (76), Expect = 0.59
Identities = 53/203 (26%), Positives = 66/203 (32%), Gaps = 37/203 (18%)
Query: 158 DYGQPRSPARPQPGEGPGGPGGPPEVSRGEEGRISESPEVTRLSRGRGRPRLLT------ 211
D QP P RP P P P R + SP TR G + T
Sbjct: 1098 DPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGAPKSPGTTRKDNIG 1157
Query: 212 ---PSPTTDL----HSGLQMRRARSPDLFTPLSRPPSPLSLPRPRSAPARRPPAPSGDTA 264
PSP L +G R P +S P S R++ R P T+
Sbjct: 1158 RSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQS-----HARASAGRLTPESQSKTS 1212
Query: 265 PPARPHT----PLSRIDVRPP-LDWGPQRQTLSRP------PTPRRGPPS--EAGGGKPP 311
++ T PL PP P Q L P P P+ GP E PP
Sbjct: 1213 ETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPP 1272
Query: 312 RS------PQHWSQEPRTQAHSG 328
RS P S +P+ + SG
Sbjct: 1273 RSRSSHSLPSEASSQPQQEQPSG 1295
Score = 32.3 bits (72), Expect = 1.7
Identities = 63/258 (24%), Positives = 88/258 (34%), Gaps = 37/258 (14%)
Query: 501 PPHTEPDSPSPVLQGEESSERESLPES----------LELSSPRSPETDWGRP------- 543
P H +P S S + SS R S +S L + R+P G P
Sbjct: 1027 PQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPI 1086
Query: 544 ------PGGDKDLASPHLGLGSPRVSRASSPEGR----HLPSPQLGTKAPVARPRMSAQE 593
P KD A P L P R +P R P P G ++P +
Sbjct: 1087 DAQPATPLPQKDPAQP-LEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGAP 1145
Query: 594 QLERMRRNQECGRPFPRPTSPRLLTLGRTLSPARRQPDVEQRPVVGHSGAQKWLRSSGSW 653
+ R GR P P + S AR P + R V S Q R+S
Sbjct: 1146 KSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTAR--PTIPPRAGV-ISAPQSHARASAGR 1202
Query: 654 SSPRNTTPYLPTSEGHRERVLSLSQALATEASQWHRMMTGGNLDSQGDPLPGV--PLPPS 711
+P + + TS+G L + L +A+ + +PL V P+P S
Sbjct: 1203 LTPESQSKTSETSKGST----FLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQS 1258
Query: 712 DPTRQETPPPRSPPVANS 729
P PP+ PP + S
Sbjct: 1259 GPQPNLETPPQPPPRSRS 1276
Score = 30.8 bits (68), Expect = 5.0
Identities = 29/125 (23%), Positives = 45/125 (36%), Gaps = 25/125 (20%)
Query: 497 PQKPPPHTEPDSPSPVLQGEESSERESLPESLELSSPRSPETDWGRPPGGDKDLASPHLG 556
PQ+PPP + SP+P + E +P+SP T R + SP G
Sbjct: 1123 PQRPPPPSGARSPAPTRK--------------EFGAPKSPGTT--RKDNIGRSQPSPQAG 1166
Query: 557 LGSPRVSRASS------PEGRHLPSPQLGTKAPVARPRMSAQEQLERMRRNQECGRPFPR 610
L P + S+ P + +PQ +A R +Q + + P
Sbjct: 1167 LAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTF---LPE 1223
Query: 611 PTSPR 615
P P+
Sbjct: 1224 PLKPQ 1228
>gi|41393057 connector enhancer of kinase suppressor of Ras 2 [Homo
sapiens]
Length = 1034
Score = 54.7 bits (130), Expect = 3e-07
Identities = 29/93 (31%), Positives = 50/93 (53%), Gaps = 6/93 (6%)
Query: 59 GWLHKQDSSGL---RLWKRRWFVLSGHCLFYYKDSREESVLGSVLLPSYNIRPDGPGAPR 115
GWL K+ + + WK+ WFVL L++Y + +E G + LP + I D R
Sbjct: 575 GWLWKKKDAKSYFSQKWKKYWFVLKDASLYWYINEEDEKAEGFISLPEFKI--DRASECR 632
Query: 116 GRRFTFTAEHPGMRTYVLAADTLEDLRGWLRAL 148
+++ F A HP ++++ AA+ L+D+ WL +
Sbjct: 633 -KKYAFKACHPKIKSFYFAAEHLDDMNRWLNRI 664
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 54.3 bits (129), Expect = 4e-07
Identities = 61/226 (26%), Positives = 85/226 (37%), Gaps = 49/226 (21%)
Query: 168 PQPGEGPGGPGGP--PEVSRGEEGRISE----SPEVTRLSRGRGRPRLLTPSPTTDLHSG 221
P PG GPG P GP + G ++ +P V+ ++ G P L P P
Sbjct: 180 PGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNG---PAALLPLPKPAAPGT 236
Query: 222 LQMRRARSPDLFTPLSRPPSPLSLPRPRSAPARRPPAPSGDTAPPARPHTPLSRIDVRPP 281
+ ++P F + PP+P + P P +APA PA APP P P
Sbjct: 237 V----IQTPP-FVGAAAPPAPAA-PSPPAAPAPAAPA----AAPPPPPPAPA-------- 278
Query: 282 LDWGPQRQTLSRPPTPRRGPPSEAGGGKPPRSPQHWSQ---EPRTQAHSGSPTYLQLPPR 338
TL+RPP GPP+ A PP + Q+ P +G P + P
Sbjct: 279 --------TLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPG 330
Query: 339 P--------PGTRA---SMVLLPGPPLESTFHQSLETDTLLTKLCG 373
P PG +A V+ PP T S T + + G
Sbjct: 331 PGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIG 376
Score = 36.2 bits (82), Expect = 0.12
Identities = 56/212 (26%), Positives = 79/212 (37%), Gaps = 28/212 (13%)
Query: 145 LRALGRASRAEGDDYGQPRSPARPQPGE-GPGGPGGPPEVSRGEEGRISESPEVTRLSRG 203
L A G AS A G A P P P PG P + +G G +++S LSR
Sbjct: 361 LAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQS-----LSR- 414
Query: 204 RGRPRLLTPSPTTDLHSGLQMRRARSPDLFTP-LSRPPSPLSLPRPRSAPARRPPAPSGD 262
TP+ TT SG+ R +P + P L +PP + + P S +
Sbjct: 415 -------TPTATT---SGI--RATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMVLVRSEN 462
Query: 263 TAPPARPHTPLSRIDVRPPLDWGPQRQTLSRPPTPRRGPPSEAGGGKPPRSPQHWSQ-EP 321
P L+++ + PQ RP TP PP + + P +P Q P
Sbjct: 463 GQLLMIPQQALAQMQAQAHAQ--PQTTMAPRPATPTSAPPVQISTVQAPGTPIIARQVTP 520
Query: 322 RTQAHSGSPTYLQLPP-----RPPGTRASMVL 348
T S + P R PG + +VL
Sbjct: 521 TTIIKQVSQAQTTVQPSATLQRSPGVQPQLVL 552
Score = 33.5 bits (75), Expect = 0.78
Identities = 51/184 (27%), Positives = 61/184 (33%), Gaps = 24/184 (13%)
Query: 171 GEGPGGPG-GPPEVSRGEEGRISESPEVTRLSRGRGRP-RLLTPSPTTDL---HSGLQMR 225
G G G GP + G G E P R G G P R PSP L
Sbjct: 65 GSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAA 124
Query: 226 RARSPDLFTPLSRPPSPLSLPRPRSAPARRPPAPSGDTAPPARPHTPLSRIDVRPPLDWG 285
+ R P P S +P + A PAP+G A PA P +R P G
Sbjct: 125 KLRPP----PEGSAGSCAPVPAAAAVAAGPEPAPAG-PAKPAGPAALAARAGPGPGPGPG 179
Query: 286 PQRQTLSRPPTPRRGPPSEAG-----GGKPPRSPQHWSQEPRTQAHSGSPTYLQLPPRP- 339
P P P G P+ G G H + P + P L P+P
Sbjct: 180 P-------GPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPA 232
Query: 340 -PGT 342
PGT
Sbjct: 233 APGT 236
Score = 32.0 bits (71), Expect = 2.3
Identities = 28/82 (34%), Positives = 32/82 (39%), Gaps = 11/82 (13%)
Query: 693 GGNLDSQGDPLPGVPLPPSDPTRQETPPP---RSPPVANSGSTGFSRRGSGRGGG--PTP 747
GG G P P PL P+ P PP R PP ++GS + G P P
Sbjct: 99 GGGPQRPGPPSPRRPLVPAGP----APPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAP 154
Query: 748 WGPAWDAGIAPPVLPQDEGAWP 769
GPA AG P L G P
Sbjct: 155 AGPAKPAG--PAALAARAGPGP 174
Score = 30.8 bits (68), Expect = 5.0
Identities = 69/311 (22%), Positives = 100/311 (32%), Gaps = 62/311 (19%)
Query: 162 PRSPARPQPGEGPGGPGGPPEVSRG--------EEGRISESPEVTRLSRG----RGRP-- 207
P PA PG P GPP + G +P + G G+P
Sbjct: 272 PPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGP 331
Query: 208 --RLLTPSPTTDLHSGLQMRRARSPDLFTPLSRPPSPL------------SLPRPRSAPA 253
P+P S ++ +A P T + P+ +LP P + P
Sbjct: 332 GAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPP 391
Query: 254 RRPPAPSGDTAPPARPHTPLSRIDVRPPLDWGPQRQTLS------RPPTPRRGPPSEAGG 307
P P+G P + P R TL+ R P P + P +
Sbjct: 392 PAPGTPTG--LPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNF 449
Query: 308 GKPP-----RS--------PQHWSQEPRTQAHSGSPTYLQLPPRP------PGTRASMVL 348
PP RS PQ + + QAH+ T + PRP P + S V
Sbjct: 450 QLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQT--TMAPRPATPTSAPPVQISTVQ 507
Query: 349 LPGPPLESTFHQSLETDTLLTKLCGQDRLLRRLQEEIDQKQEEKEQLEAALELTRQQLGQ 408
PG P+ + T T + K Q + + + + + QL LG
Sbjct: 508 APGTPIIA----RQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGT 563
Query: 409 ATR-EAGAPGR 418
AT + G P R
Sbjct: 564 ATAVQTGTPQR 574
>gi|54860079 nadrin isoform 1 [Homo sapiens]
Length = 881
Score = 54.3 bits (129), Expect = 4e-07
Identities = 60/218 (27%), Positives = 82/218 (37%), Gaps = 39/218 (17%)
Query: 161 QPRSPARPQPGEGPGGPGGPPEVSRGEE----GRISESPEVTRL--SRGRGRP------- 207
QP P P GP PP+ SR E G + S + S G G P
Sbjct: 524 QPPLPPTDGSTVVPAGPEPPPQSSRAESSSGGGTVPSSAGILEQGPSPGDGSPPKPKDPV 583
Query: 208 RLLTPSP---TTDLHSGLQMRRARSPDLFTPLSRP-----PSPLSLPRPRSAPARRPPAP 259
P+P + + SG +A + + +P PSP +L R PA PP P
Sbjct: 584 SAAVPAPGRNNSQIASGQNQPQAAAGSHQLSMGQPHNAAGPSPHTLRRAVKKPAPAPPKP 643
Query: 260 SGDTAPPARPHTPLSRIDVRPPLDWGPQRQTLSRPPTPRRGPPSEAGGGKPPRSPQHWSQ 319
PP P S + P P +PPT PP++ G +PP P SQ
Sbjct: 644 GNP--PPGHPGGQSSSGTSQHPPSLSP------KPPTRSPSPPTQHTG-QPPGQPSAPSQ 694
Query: 320 EPRTQAHSGSPTYLQLPPRPPGTRASMVLLPGPPLEST 357
+ +S S + +Q P PP P PP ++T
Sbjct: 695 LSAPRRYSSSLSPIQAPNHPP---------PQPPTQAT 723
Score = 49.3 bits (116), Expect = 1e-05
Identities = 57/222 (25%), Positives = 74/222 (33%), Gaps = 52/222 (23%)
Query: 160 GQPRSPARP----------QPGEGPGGPGGPPEVSRGEEGRISESPEVTRLSRGRGRPRL 209
GQP + A P +P P PG PP G + S LS +P
Sbjct: 616 GQPHNAAGPSPHTLRRAVKKPAPAPPKPGNPPPGHPGGQSSSGTSQHPPSLSP---KPPT 672
Query: 210 LTPSPTTDLHSGLQMRRARSPDLFTPLSRPPSPLSLPRPR---------SAPARRPPAPS 260
+PSP T H+G P +P +P L PR AP PP P
Sbjct: 673 RSPSPPTQ-HTG------------QPPGQPSAPSQLSAPRRYSSSLSPIQAPNHPPPQPP 719
Query: 261 GDTAP----------PARPHTPLSRIDVRPPLDWGPQRQT-LSRPPTPRRGP----PSEA 305
P P P S + P PQ T S PP ++ P P
Sbjct: 720 TQATPLMHTKPNSQGPPNPMALPSEHGLEQPSHTPPQTPTPPSTPPLGKQNPSLPAPQTL 779
Query: 306 GGGKPPRSPQHWS--QEPRTQAHSGSPTYLQLPPRPPGTRAS 345
GG P + H PR + + PP+PPG ++
Sbjct: 780 AGGNPETAQPHAGTLPRPRPVPKPRNRPSVPPPPQPPGVHSA 821
Score = 36.2 bits (82), Expect = 0.12
Identities = 61/270 (22%), Positives = 87/270 (32%), Gaps = 54/270 (20%)
Query: 493 GLGGPQKPPPHTEPDSPSPVLQGEESSERESLPES------LELSSPRS---PETDWGRP 543
G G P KP P+P + + ++ P++ L + P + P R
Sbjct: 572 GDGSPPKPKDPVSAAVPAPGRNNSQIASGQNQPQAAAGSHQLSMGQPHNAAGPSPHTLRR 631
Query: 544 PGGDKDLASPHLGLGSPRVSRASSPEGRHLPSPQLGTKAPVARPRMSAQEQLERMRRNQE 603
A P G P S G P L K P P Q
Sbjct: 632 AVKKPAPAPPKPGNPPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSPPTQHT--------- 682
Query: 604 CGRPFPRPTSPRLLTLGR----TLSPARR------QPDVEQRPVVGHSGAQKW------L 647
G+P +P++P L+ R +LSP + QP + P++ + L
Sbjct: 683 -GQPPGQPSAPSQLSAPRRYSSSLSPIQAPNHPPPQPPTQATPLMHTKPNSQGPPNPMAL 741
Query: 648 RSSGSWSSPRNTTPYLPTSE-----GHRERVLSLSQALATEASQWHRMMTGGNLDSQGDP 702
S P +T P PT G + L Q LA GGN ++
Sbjct: 742 PSEHGLEQPSHTPPQTPTPPSTPPLGKQNPSLPAPQTLA-----------GGNPETAQPH 790
Query: 703 LPGVPLP---PSDPTRQETPPPRSPPVANS 729
+P P P R PPP PP +S
Sbjct: 791 AGTLPRPRPVPKPRNRPSVPPPPQPPGVHS 820
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 54.3 bits (129), Expect = 4e-07
Identities = 75/275 (27%), Positives = 96/275 (34%), Gaps = 47/275 (17%)
Query: 107 RPDGPGAPRGRRFTFTAEHPGMRTYVLAADTLEDLRGWLRALGRASRAEGDDYGQPRSPA 166
RP P +P T A HP + LA D G +L ++ E
Sbjct: 1286 RPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTE----------- 1334
Query: 167 RPQPGEGPGGPGGPPEVSRGEEGRISESPEVTRLSRGRGRPRLLTPSPTTDLHSGLQMRR 226
P PGG P +S G G SP+V G P P+P+ L SG R
Sbjct: 1335 -----TVPATPGGEPPLSGGSSGLSLSSPQVP------GSP-FSYPAPSPSLSSGGLPRT 1382
Query: 227 ARSPDLFTP-LSRPPSPLSLPRPRSAPARRPPAPSGDTAPPARPHTPLS---RIDVRPPL 282
FTP S P PL LP P R SG A P T L + + PL
Sbjct: 1383 PGRDFSFTPTFSEPSGPLLLP-VCPLPTGRRDERSGPLASPVLLETGLPLPLPLPLPLPL 1441
Query: 283 DWGPQRQTLSRPPTP----------RRGPPSEAGGGKPPRSPQHWSQEPRTQAHSGSPTY 332
+ +R PTP PP + G+P RSP P + G
Sbjct: 1442 ALPAVLRAQARAPTPLPPLLPAPLASCPPPMKRKPGRPRRSP------PSMLSLDGP--- 1492
Query: 333 LQLPPRPPGTRASMVLLPGPPLESTFHQSLETDTL 367
L PP ++LLPG P F + + T+
Sbjct: 1493 LVRPPAGAALGRELLLLPGQPQTPVFPSTHDPRTV 1527
Score = 42.7 bits (99), Expect = 0.001
Identities = 49/175 (28%), Positives = 59/175 (33%), Gaps = 35/175 (20%)
Query: 162 PRSPARPQPGEGPGGPGGPP-----------EVSRGEEGRISESPEVTRLSRGRGRPRLL 210
P PA P E PG P GPP + G +SP L P
Sbjct: 436 PLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTLESSPAGPEKP 495
Query: 211 TPSPTTDLHSGLQMRRA-----RSPDLFTPLSRPPSPLSLPRPRSAP-----ARRPPAPS 260
S + + L+ +R R PD T L SP+S + +P P
Sbjct: 496 HDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQLSPLAPFGTNSQPGFR 555
Query: 261 GDTAPPARPH---------TPLSRIDVRPPLDWGPQRQTLSRPPTPRRGPPSEAG 306
G T P +RP TPL D LD G L P P GPP AG
Sbjct: 556 GPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLG-----LGPRPPPEPGPPDPAG 605
Score = 39.3 bits (90), Expect = 0.014
Identities = 49/185 (26%), Positives = 62/185 (33%), Gaps = 36/185 (19%)
Query: 167 RPQPGEGPGGPGG----PPEVSR---GEEGRISESPEVTRLSRGRGRPRLLTPSPTTDLH 219
RP P GP P G EV+ G+ SE + + S G P+ +
Sbjct: 593 RPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPIT 652
Query: 220 SGLQMRRARSPDLFTPLSRP---PSPLSLPRPRSAPARRPPAPSGDTAPPARPHTPLSRI 276
S P + TP + PS L+ P P PP P PP +P P+
Sbjct: 653 SA----DCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPP 708
Query: 277 DVRPPLDWGPQRQTLSRPPTPRRGPPSEAGGGKPPRSPQHWSQEPRTQAHSGSPTYLQLP 336
PP P ++ PP P PP G PP P LP
Sbjct: 709 LPPPPPPPPPAHPAVTVPPPPLPAPP-----GVPP-----------------PPILPPLP 746
Query: 337 PRPPG 341
P PPG
Sbjct: 747 PFPPG 751
Score = 37.7 bits (86), Expect = 0.041
Identities = 70/238 (29%), Positives = 83/238 (34%), Gaps = 59/238 (24%)
Query: 170 PGEGPGGPGGPP-EVSRGEEGRISESPEVTRLSRGRGRPRLLTPSPTT---DLHSGLQMR 225
P E P PP V E E PE LS+ LL+P P + L
Sbjct: 1200 PEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAM--LLSPEPPAKEVEARPPLSPE 1257
Query: 226 RARSPDLFTPLSRPPSPLSLPRPRSAP-----ARRPPAP---------SGDTAPPA---- 267
RA DL P P+ LP P P RPP+P S + PP
Sbjct: 1258 RAPEHDLEV---EPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAE 1314
Query: 268 --RPHTP-----LSRIDV----------RPPLDWGPQRQTLSRPPTP------RRGPPSE 304
PHTP L++ PPL G +LS P P PS
Sbjct: 1315 DHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSL 1374
Query: 305 AGGGKPPRSPQHWSQEPRTQAHSGSPTYLQLPPRPPGTR-------ASMVLL-PGPPL 354
+ GG P + +S P SG P L + P P G R AS VLL G PL
Sbjct: 1375 SSGGLPRTPGRDFSFTPTFSEPSG-PLLLPVCPLPTGRRDERSGPLASPVLLETGLPL 1431
Score = 35.0 bits (79), Expect = 0.27
Identities = 75/287 (26%), Positives = 95/287 (33%), Gaps = 68/287 (23%)
Query: 497 PQKPPPHTEPDSPSPVLQGEESSERESLPESL-------------ELSSPRSPETDWGRP 543
P PP P SP P + ++S PE L L+ +S ET
Sbjct: 1281 PLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTET-VPAT 1339
Query: 544 PGGDKDLA--SPHLGLGSPRVSRASSPEGRHLPSPQLG----------------TKAPVA 585
PGG+ L+ S L L SP+V SP PSP L T + +
Sbjct: 1340 PGGEPPLSGGSSGLSLSSPQV--PGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPS 1397
Query: 586 RPRMSAQEQLERMRRNQ-----------ECGRPFPRPTS-PRLLTLGRTLSPARRQPD-- 631
P + L RR++ E G P P P P L L L R P
Sbjct: 1398 GPLLLPVCPLPTGRRDERSGPLASPVLLETGLPLPLPLPLPLPLALPAVLRAQARAPTPL 1457
Query: 632 VEQRPVVGHSGAQKWLRSSGSWSSPRNTTPYLPTSEG-----------HRERVLSLSQAL 680
P S R G PR + P + + +G RE +L Q
Sbjct: 1458 PPLLPAPLASCPPPMKRKPG---RPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQ 1514
Query: 681 ATEASQWHRMMTGG-NLDSQGDPLPGVPLPPSDPTRQETPPPRSPPV 726
H T + + G P P PLPP P PPP PPV
Sbjct: 1515 TPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPP-----PPPPPPPV 1556
Score = 33.1 bits (74), Expect = 1.0
Identities = 35/140 (25%), Positives = 50/140 (35%), Gaps = 8/140 (5%)
Query: 226 RARSPDLFTPLSRPPSPLSLPRPRSAPARRP-PAPSGDTAPPARPHTPLSRIDVRPPLDW 284
+A+ D T PP + P P A P P PP T + R D
Sbjct: 369 KAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGAR---DS 425
Query: 285 GPQRQTLSRPPTPRRGPPSEAGGGKPPRSPQHWSQEPRTQAHSGSPTYLQLPPRPPGTRA 344
G R+ + PP P P ++ G PP P + + G PT+ P P +
Sbjct: 426 GEFRRAPAPPPLPPAEPLAKEKPGTPPGPP---PPDTNSMELGGRPTF-GWSPEPCDSPG 481
Query: 345 SMVLLPGPPLESTFHQSLET 364
+ L P H SL++
Sbjct: 482 TPTLESSPAGPEKPHDSLDS 501
Score = 32.7 bits (73), Expect = 1.3
Identities = 32/127 (25%), Positives = 44/127 (34%), Gaps = 14/127 (11%)
Query: 239 PPSPLSLPRPRSAPARRPPAPSGDTAPPARPHTPLSRIDVRPPLDWGPQRQTLSRPPTPR 298
P +P++ SA +P + A A P + + PP + P PP P
Sbjct: 647 PSAPIT-----SADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPL------PPPPP 695
Query: 299 RGPPSEAGGGKPPRSPQHWSQEPRTQAHSGSPTYLQLPPRPPGTRASMVLLPGPPLESTF 358
PP PP P P A + P L P PPG +L P PP
Sbjct: 696 PPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPL---PAPPGVPPPPILPPLPPFPPGL 752
Query: 359 HQSLETD 365
++ D
Sbjct: 753 FPVMQVD 759
Score = 31.6 bits (70), Expect = 3.0
Identities = 22/61 (36%), Positives = 25/61 (40%), Gaps = 16/61 (26%)
Query: 702 PLPGVPLPPSDPTRQETPPPRSPPVANSGSTGFSRRGSGRGGGPTPWGPAWDAGIAPPVL 761
P PG P+PP P PPP PP A+ T P P PA PP+L
Sbjct: 699 PQPGFPMPPPLP-----PPPPPPPPAHPAVT-----------VPPPPLPAPPGVPPPPIL 742
Query: 762 P 762
P
Sbjct: 743 P 743
Score = 31.2 bits (69), Expect = 3.9
Identities = 23/63 (36%), Positives = 29/63 (46%), Gaps = 6/63 (9%)
Query: 707 PLPPSDPTRQE---TPPPRSPPVANSGSTGFSRRGSGRGGGP--TPWGPAWDAGIAPPVL 761
PLPP++P +E TPP PP NS G R G P +P P ++ A P
Sbjct: 436 PLPPAEPLAKEKPGTPPGPPPPDTNSMELG-GRPTFGWSPEPCDSPGTPTLESSPAGPEK 494
Query: 762 PQD 764
P D
Sbjct: 495 PHD 497
>gi|157785645 SPEG complex locus [Homo sapiens]
Length = 3267
Score = 54.3 bits (129), Expect = 4e-07
Identities = 106/439 (24%), Positives = 147/439 (33%), Gaps = 110/439 (25%)
Query: 213 SPTTDLH-SGLQMRRARSPDLFTPLSRPPSPLSLPRPRSAPARRPPAPSGDTAPPARPHT 271
S +DL+ S + R R+ L +S P S L P P AP PP
Sbjct: 250 SVASDLYGSAFSLYRGRA--LSIHVSVPQSGLRREEPDLQPQLASEAPRRPAQPP----- 302
Query: 272 PLSRIDVRPPLDWGPQRQTLSRPPTPR---RGPPS-EAGGGKPPRSPQHWSQEP-----R 322
P + L PP+PR R PP A P SP +QEP
Sbjct: 303 --------------PSKSALLPPPSPRVGKRSPPGPPAQPAATPTSPHRRTQEPVLPEDT 348
Query: 323 TQAHSGSPTYLQLPPRPPGTRASMVLLPGPPLESTFHQSLETDTLLTKLCGQDRLLR--- 379
T P GT S P PL E L+ L RL+R
Sbjct: 349 TTEEKRGKKSKSSGPSLAGTAESR---PQTPLS-------EASGRLSALGRSPRLVRAGS 398
Query: 380 RLQEEIDQKQEEKEQLE------------------AALELTRQQL-------GQATREAG 414
R+ +++ +E + LE +LE + + G + E
Sbjct: 399 RILDKLQFFEERRRSLERSDSPPAPLRPWVPLRKARSLEQPKSERGAPWGTPGASQEELR 458
Query: 415 APGRAWGRQRLLQDRLVSVRATLCHLTQERERVWDTYSGLEQELGTLRETLEYLLHLGSP 474
APG R+RL Q + A+L T++R D QELG +R + S
Sbjct: 459 APGSVAERRRLFQQK----AASLDERTRQRSPASDLELRFAQELGRIRRST-------SR 507
Query: 475 QDRVSAQQQLWMVEDTLAGLGGPQKPPPHTEPDSPSPVLQGEESSERESLPESLELSSPR 534
++ V + + L P +PP + P +P + R P + + SP
Sbjct: 508 EELVRSHESLRATLQRAPSPREPGEPPLFSRPSTP--------KTSRAVSPAAAQPPSPS 559
Query: 535 SPETDWGRPPGGDKDLASPHLGLGSPRVSRASSPEGRHLPSPQLGTKAPVARPRMSAQEQ 594
S E PG + P R+ P GR P + P R Q
Sbjct: 560 SAE-----KPGDE------------PGRPRSRGPAGRTEPG-----EGPQQEVRRRDQFP 597
Query: 595 LERMRRNQECGRPFPRPTS 613
L R R QEC P P P +
Sbjct: 598 LTRSRAIQECRSPVPPPAA 616
Score = 49.3 bits (116), Expect = 1e-05
Identities = 80/326 (24%), Positives = 114/326 (34%), Gaps = 63/326 (19%)
Query: 4 SRPRSSLSLASSASTISSLSSLSPKKPTRAVNKIHAFGKRGNALRRDPNLPVHIRGWLHK 63
SRP++ LS AS + S + +R ++K+ F +R +L R + P +R W+
Sbjct: 371 SRPQTPLSEASGRLSALGRSPRLVRAGSRILDKLQFFEERRRSLERSDSPPAPLRPWVPL 430
Query: 64 QDSSGLRLWKRRWFVLSGHCLFYYKDSREESVLGSVLLPSYNIRPDGPGAPRGRRFTFTA 123
+ + L K S + G+ +R G A R R F A
Sbjct: 431 RKARSLEQPK----------------SERGAPWGTPGASQEELRAPGSVAERRRLFQQKA 474
Query: 124 EHPGMRTYVLAADTLEDLRGWLRALGRASRAEGDDY---GQPRSPARPQPGEGPGGPGGP 180
RT + + +LR + + LGR R+ + A Q P PG P
Sbjct: 475 ASLDERTRQRSPASDLELR-FAQELGRIRRSTSREELVRSHESLRATLQRAPSPREPGEP 533
Query: 181 PEVSRGEEGRISESPEVTRLSRGRGRPRLLTPSPTTDLHSGLQMRRARSPDLFTPLSRPP 240
P SR P+T S RA SP ++PP
Sbjct: 534 PLFSR----------------------------PSTPKTS-----RAVSP----AAAQPP 556
Query: 241 SPLSLPRPRSAPAR-RPPAPSGDTAPPARPHTPLSRIDVRPPLDWGPQRQTLSRPPTPRR 299
SP S +P P R R P+G T P P + R D P ++ S P P
Sbjct: 557 SPSSAEKPGDEPGRPRSRGPAGRTEPGEGPQQEVRRRDQFPLTRSRAIQECRSPVPPPAA 616
Query: 300 GPPSEAGGGKPPRSPQHWSQEPRTQA 325
PP P R +EP QA
Sbjct: 617 DPPEARTKAPPGR-----KREPPAQA 637
Score = 46.6 bits (109), Expect = 9e-05
Identities = 90/342 (26%), Positives = 124/342 (36%), Gaps = 81/342 (23%)
Query: 133 LAADTLEDLRGWLR--ALGRASRAEGDDYGQP--------RSPARPQPGEGPGG----PG 178
L LE L G R + RA+ +E + QP +S + Q P G G
Sbjct: 2087 LRGPLLESLGGRARDPRMARAASSEAAPHHQPPLENRGLQKSSSFSQGEAEPRGRHRRAG 2146
Query: 179 GPPEVSRGEEG--RISESPEVTRLSRGRGRPRLLTPSPTTDLHSGLQMRRARSPDLFTPL 236
P E+ G R+ ESP ++ LS + PS R +P TP
Sbjct: 2147 APLEIPVARLGARRLQESPSLSALSEAQ-------PSSPA---------RPSAPKPSTPK 2190
Query: 237 SRPPSPLSLPRPRSAPARRPPAPSGDTAPPARPHTPLSRIDVRPPLDWGPQR-QTLSRPP 295
S PS + P AP P P+ D AP RP P+ PP PQ QTL+ P
Sbjct: 2191 SAEPSATT---PSDAPQPPAPQPAQDKAPEPRPE-PVRASKPAPP----PQALQTLALPL 2242
Query: 296 T-----------------PRRGPPSEAGGGKP-------PRSPQHWSQEPRTQAHSGSPT 331
T P +GP + KP SP + E R + G P
Sbjct: 2243 TPYAQIIQSLQLSGHAQGPSQGPAAPPSEPKPHAAVFARVASPPPGAPEKRVPSAGGPPV 2302
Query: 332 YLQ------LPPRPPGTRASMV--LLPGPPLESTFHQSLETD-----TLLTKLCGQDRLL 378
+ +PPRP + +S + L E+ F +S E+ LL++ ++R
Sbjct: 2303 LAEKARVPTVPPRPGSSLSSSIENLESEAVFEAKFKRSRESPLSLGLRLLSRSRSEERGP 2362
Query: 379 RRLQEEID---QKQEEKEQLEAALELTRQQLGQATREAGAPG 417
R EE D + LE R + Q R G PG
Sbjct: 2363 FRGAEEEDGIYRPSPAGTPLELVRRPERSRSVQDLRAVGEPG 2404
Score = 42.4 bits (98), Expect = 0.002
Identities = 76/301 (25%), Positives = 100/301 (33%), Gaps = 77/301 (25%)
Query: 497 PQKPPPHTEPDSPSPVLQGEESSERESLPESLELSSPRSPETDWGRP-----PGGDKDLA 551
P++PPP S L SE E L E + P PE R P D+ L
Sbjct: 1909 PRRPPP-------SGGLSSSSDSEEEELEELPSVPRPLQPEFSGSRVSLTDIPTEDEALG 1961
Query: 552 SPHLGLGSP----RVSRASSPEGRHLPSPQLGTKAPVARPRMSAQEQLERMRRNQECGRP 607
+P G +P RA S + + PSP+ +P P A + +RR
Sbjct: 1962 TPETGAATPMDWQEQGRAPSQD-QEAPSPE-ALPSPGQEPAAGASPRRGELRRGSSAESA 2019
Query: 608 FPRPTSPRLLTLGRTLS-------PARRQPDV-EQRPVVGHSGA-----------QKWLR 648
PR PR LGR L P RR P R G G Q+ LR
Sbjct: 2020 LPR-AGPR--ELGRGLHKAASVELPQRRSPSPGATRLARGGLGEGEYAQRLQALRQRLLR 2076
Query: 649 SSGSWSSPRNTTPYLPTSEGHRERVLSLSQALATEASQWH------RMMTGGNLDSQGDP 702
L S G R R +++A ++EA+ H R + + SQG+
Sbjct: 2077 GGPEDGKVSGLRGPLLESLGGRARDPRMARAASSEAAPHHQPPLENRGLQKSSSFSQGEA 2136
Query: 703 LP-------GVPLP------------------------PSDPTRQETPPPRSPPVANSGS 731
P G PL PS P R P P +P A +
Sbjct: 2137 EPRGRHRRAGAPLEIPVARLGARRLQESPSLSALSEAQPSSPARPSAPKPSTPKSAEPSA 2196
Query: 732 T 732
T
Sbjct: 2197 T 2197
Score = 39.7 bits (91), Expect = 0.011
Identities = 61/263 (23%), Positives = 82/263 (31%), Gaps = 67/263 (25%)
Query: 153 RAEGDDYGQPRSPARPQPGEGPGGPG--------------------GPPEVSRGEEG--- 189
RA D P A P PG+ P GP E+ RG
Sbjct: 1978 RAPSQDQEAPSPEALPSPGQEPAAGASPRRGELRRGSSAESALPRAGPRELGRGLHKAAS 2037
Query: 190 -----RISESPEVTRLSRG------------RGRPRLLTPSPTTDLHSGLQ-------MR 225
R S SP TRL+RG R RLL P SGL+
Sbjct: 2038 VELPQRRSPSPGATRLARGGLGEGEYAQRLQALRQRLLRGGPEDGKVSGLRGPLLESLGG 2097
Query: 226 RARSPDLFTPLSRPPSPLSLPRPRSAPARRPPAPSGDTAPPARPH--------TPLSRID 277
RAR P + S +P P + ++ + S A P H P++R+
Sbjct: 2098 RARDPRMARAASSEAAPHHQPPLENRGLQKSSSFSQGEAEPRGRHRRAGAPLEIPVARLG 2157
Query: 278 VR-----PPLD-------WGPQRQTLSRPPTPRRGPPSEAGGGKPPRSPQHWSQEPRTQA 325
R P L P R + +P TP+ PS P+ P + +
Sbjct: 2158 ARRLQESPSLSALSEAQPSSPARPSAPKPSTPKSAEPSATTPSDAPQPPAPQPAQDKAPE 2217
Query: 326 HSGSPTYLQLPPRPPGTRASMVL 348
P P PP ++ L
Sbjct: 2218 PRPEPVRASKPAPPPQALQTLAL 2240
Score = 34.3 bits (77), Expect = 0.46
Identities = 28/97 (28%), Positives = 37/97 (38%), Gaps = 1/97 (1%)
Query: 162 PRSPARPQPGEGPGGPGGPPEVSRGEEGRISESPEVTRLSRGRGRPRLLTPSPTTDLHSG 221
PR PA+P P + P P V + P T S R + P TT
Sbjct: 295 PRRPAQPPPSKSALLPPPSPRVGKRSPPGPPAQPAATPTSPHRRTQEPVLPEDTTTEEKR 354
Query: 222 LQMRRARSPDLF-TPLSRPPSPLSLPRPRSAPARRPP 257
+ ++ P L T SRP +PLS R + R P
Sbjct: 355 GKKSKSSGPSLAGTAESRPQTPLSEASGRLSALGRSP 391
Score = 33.5 bits (75), Expect = 0.78
Identities = 76/285 (26%), Positives = 98/285 (34%), Gaps = 50/285 (17%)
Query: 493 GLGGPQKPP--PHTEPDSP-----SPVLQGEESSERESLPESLELSSPRSPETDWGRPPG 545
G P PP P P SP PVL E+++ E + + S P T RP
Sbjct: 317 GKRSPPGPPAQPAATPTSPHRRTQEPVLP-EDTTTEEKRGKKSKSSGPSLAGTAESRPQT 375
Query: 546 GDKDLASPHLGLG-SPRVSRASSPEGRHLPSPQLGTKAPVARPRMSAQEQLERMRRNQEC 604
+ + LG SPR+ RA S R L Q E RR+ E
Sbjct: 376 PLSEASGRLSALGRSPRLVRAGS---RILDKLQF----------------FEERRRSLER 416
Query: 605 GRPFPRPTSPRL-LTLGRTLSPARRQPDVEQRPVVGHSGA-QKWLRSSGSWSSPRNTTPY 662
P P P + L R+L QP E+ G GA Q+ LR+ GS + R
Sbjct: 417 SDSPPAPLRPWVPLRKARSLE----QPKSERGAPWGTPGASQEELRAPGSVAERRRLFQQ 472
Query: 663 LPTSEGHRERVLS----LSQALATEASQWHRMMTGGNLDSQGDPL------------PGV 706
S R R S L A E + R + L + L PG
Sbjct: 473 KAASLDERTRQRSPASDLELRFAQELGRIRRSTSREELVRSHESLRATLQRAPSPREPGE 532
Query: 707 PLPPSDPTRQETPPPRSPPVANSGSTGFSRRGSGRGGGPTPWGPA 751
P S P+ +T SP A S + + G P GPA
Sbjct: 533 PPLFSRPSTPKTSRAVSPAAAQPPSPSSAEKPGDEPGRPRSRGPA 577
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 54.3 bits (129), Expect = 4e-07
Identities = 62/220 (28%), Positives = 83/220 (37%), Gaps = 36/220 (16%)
Query: 155 EGDDYGQPRS-PARPQ--PGEGPGGPGGPPEVSRGEEGRISESPEVTRLSRGRGRPRLLT 211
+GD PRS P +PQ P +G P GPP +G + + G+P+
Sbjct: 104 QGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQ--G 161
Query: 212 PSPTTDLHSGLQMRRARSPDLFTPLSRPPSPLSLPRPRSAPARRP--PAPSGDTAP--PA 267
P P D S R +RSP P PP + P+ P +P P P G P P
Sbjct: 162 PPPQGDNKS----RSSRSPP-GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP 216
Query: 268 RPHTPLSRIDVRPPLDWGPQRQTLSRPPTPRRGPPSEAGG---------GKPPRSPQHWS 318
P P PP + Q+ PP +GPP + G GKP P
Sbjct: 217 PPGKPQG-----PPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 271
Query: 319 QEPRTQAHSGSPTYLQLPPRPPGTRASMVLLP-----GPP 353
+P+ G P Q PP G+++ P GPP
Sbjct: 272 NKPQGPPPPGKP---QGPPPQGGSKSRSSRSPPGKPQGPP 308
Score = 53.5 bits (127), Expect = 7e-07
Identities = 63/217 (29%), Positives = 82/217 (37%), Gaps = 39/217 (17%)
Query: 149 GRASRAEGDDYGQPRSPARPQPGEGPGGPGGPPEVSRGEEGRISESPEVTRLSRGRGRPR 208
G SR+ G+P+ P PQ G P GP PP +G + P+ G+P+
Sbjct: 105 GDKSRSPRSPPGKPQGPP-PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPP---GKPQ 160
Query: 209 LLTPSPTTDLHSGLQMRRARSPDLFTPLSRPPSPLSLPRPRSAPARRP--PAPSGDTAP- 265
P P D S R +RSP P PP + P+ P +P P P G P
Sbjct: 161 --GPPPQGDNKS----RSSRSPP-GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQ 213
Query: 266 ----PARPHTPLSRIDVR-------------PPLDWGPQRQTLSRPPTPRRGPPSEAG-- 306
P +P P + D + PP G Q Q PP +GPP + G
Sbjct: 214 GPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK 273
Query: 307 --GGKPPRSPQHWSQEPRTQAHSGSPTYLQLPPRPPG 341
G PP P Q P Q S S + P +P G
Sbjct: 274 PQGPPPPGKP----QGPPPQGGSKSRSSRSPPGKPQG 306
Score = 53.1 bits (126), Expect = 9e-07
Identities = 52/183 (28%), Positives = 70/183 (38%), Gaps = 18/183 (9%)
Query: 160 GQPRSPARPQPGEGPGGPGGPPEVSRGEEGRISESPEVTRLSRGRGRPRLLTPSPTTDLH 219
G+P+ P PQ G P GP PP +G + P+ G+P+ P P
Sbjct: 240 GKPQGPP-PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPP---GKPQ--GPPP----Q 289
Query: 220 SGLQMRRARSPDLFTPLSRPPSPLSLPRPRSAPARRP--PAPSGDTAPPARPHTPLSRID 277
G + R +RSP P PP + P+ P +P P P G P P P +
Sbjct: 290 GGSKSRSSRSPP-GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP--PPGKPQ 346
Query: 278 VRPPLDWGPQRQTLSRPPTPRRGPPSEAGGGKPPRSPQHWSQEPRTQAHSGSPTYLQLPP 337
PP R S P P+ P E + P P + + +G P Q PP
Sbjct: 347 GPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQP---QGPP 403
Query: 338 RPP 340
RPP
Sbjct: 404 RPP 406
Score = 51.2 bits (121), Expect = 4e-06
Identities = 67/270 (24%), Positives = 88/270 (32%), Gaps = 44/270 (16%)
Query: 497 PQKPPPHTEPDSPSPVLQGEESSERESLPESLELSSPRSPETDWGRPPGGDKDLASPHLG 556
PQ PPP +P P P QG++S S P + P+ G PP K P G
Sbjct: 89 PQGPPPPGKPQGPPP--QGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG 146
Query: 557 LGSPR-VSRASSPEGRHLPSPQLGTKAPVARPRMSAQEQLERMRRNQECGRPFPRPTSPR 615
P+ P+G P PQ K+ +R + NQ G P P P P+
Sbjct: 147 GNKPQGPPPPGKPQG---PPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPP-PPPGKPQ 202
Query: 616 LLTLGRTLSPARRQPDVEQRPVVGHSGAQKWLRSSGSWSSPRNTTPYLPTSEGHRERVLS 675
P + + Q P P P P +G +
Sbjct: 203 --------GPPPQGGNKPQGP-------------------PPPGKPQGPPPQGDNKS--- 232
Query: 676 LSQALATEASQWHRMMTGGNLDSQGDPLPGVPL--PPSDPTRQETPP----PRSPPVANS 729
A + GGN P PG P PP + + PP P+ PP
Sbjct: 233 -QSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGG 291
Query: 730 GSTGFSRRGSGRGGGPTPWGPAWDAGIAPP 759
+ SR G+ GP P G G PP
Sbjct: 292 SKSRSSRSPPGKPQGPPPQGGNQPQGPPPP 321
Score = 50.1 bits (118), Expect = 8e-06
Identities = 61/214 (28%), Positives = 80/214 (37%), Gaps = 39/214 (18%)
Query: 152 SRAEGDDYGQPRSPARPQPGEGPGGPGGPPEVSRGEEGRISESPEVTRLSRGRGRPRLLT 211
SR+ G+P+ P PQ G P GP PP +G + P+ G+P+
Sbjct: 170 SRSSRSPPGKPQGPP-PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPP---GKPQ--G 223
Query: 212 PSPTTDLHSGLQMRRARSPDLFTPLSRPPSPLSLPRPRSAPARRP--PAPSGDTAP---- 265
P P D S + ARSP P PP + P+ P +P P P G P
Sbjct: 224 PPPQGDNKS----QSARSPP-GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP 278
Query: 266 -PARPHTPLSRIDVR-------------PPLDWGPQRQTLSRPPTPRRGPPSEAG----G 307
P +P P + + PP G Q Q PP +GPP + G G
Sbjct: 279 PPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQG 338
Query: 308 GKPPRSPQHWSQEPRTQAHSGSPTYLQLPPRPPG 341
PP P Q P Q S S + P +P G
Sbjct: 339 PPPPGKP----QGPPPQGGSKSRSARSPPGKPQG 368
Score = 49.7 bits (117), Expect = 1e-05
Identities = 46/164 (28%), Positives = 61/164 (37%), Gaps = 16/164 (9%)
Query: 160 GQPRSPA-----RPQPGEGPGGPGGPPEVSRGEEGRISESPEVTRLS---RGRGRPRLLT 211
G+P+ P +PQ PG P GPP G + R S SP +G +P+
Sbjct: 261 GKPQGPPPQGGNKPQGPPPPGKPQGPPPQG-GSKSRSSRSPPGKPQGPPPQGGNQPQ--G 317
Query: 212 PSPTTDLHSGLQMRRARSPDLFTPLSRPPSPLSLPRPRSAPARRPPAPSGDTAPPARPHT 271
P P G + P P +P P +S AR PP P P
Sbjct: 318 PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGK-----PQGPPQQ 372
Query: 272 PLSRIDVRPPLDWGPQRQTLSRPPTPRRGPPSEAGGGKPPRSPQ 315
+ PP G +Q + P +GPP GG+P R PQ
Sbjct: 373 EGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPPQ 416
Score = 46.6 bits (109), Expect = 9e-05
Identities = 58/217 (26%), Positives = 77/217 (35%), Gaps = 41/217 (18%)
Query: 160 GQPRSPARPQPGEGPGGPGGPPEVSRGEEGRISESPEVTRLSRGR---------GRPRLL 210
G P+ A PQ G P GP PP +G + P+ G+ +P+
Sbjct: 34 GNPQG-APPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGP 92
Query: 211 TP--SPTTDLHSGLQMRRARSPDLFTPLSRPPSPLSLPRPRSAPARRP--PAPSGDT--- 263
P P G + R RSP P PP + P+ P +P P P G
Sbjct: 93 PPPGKPQGPPPQGDKSRSPRSPP-GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQ 151
Query: 264 --APPARPHTPLSRIDVR-------------PPLDWGPQRQTLSRPPTPRRGPPSEAG-- 306
PP +P P + D + PP G Q Q PP +GPP + G
Sbjct: 152 GPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK 211
Query: 307 --GGKPPRSPQHWSQEPRTQAHSGSPTYLQLPPRPPG 341
G PP P Q P Q + S + P +P G
Sbjct: 212 PQGPPPPGKP----QGPPPQGDNKSQSARSPPGKPQG 244
Score = 43.5 bits (101), Expect = 8e-04
Identities = 69/278 (24%), Positives = 83/278 (29%), Gaps = 44/278 (15%)
Query: 497 PQKPPPHTEPDSPSPVLQGEESSERESLPESLELSSPRSPETDWGRPPGGDKDLASPHLG 556
PQ PPP +P P P + S R S P + P+ G PP K P G
Sbjct: 150 PQGPPPPGKPQGPPPQGDNKSRSSR-SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG 208
Query: 557 LGSPR-VSRASSPEGRHLPSPQLGTKAPVARPRMSAQEQLERMRRNQECGRPFP--RPTS 613
P+ P+G P PQ K+ AR + NQ G P P +P
Sbjct: 209 GNKPQGPPPPGKPQG---PPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQG 265
Query: 614 PRLLTLGRTLSPARRQPDVEQRPVVGHSGAQKWLRSSGSWSSPRNTTPYLPTSEGHRERV 673
P + P P Q P G K S P+ P
Sbjct: 266 PPPQGGNKPQGPP--PPGKPQGPPP--QGGSKSRSSRSPPGKPQGPPPQ----------- 310
Query: 674 LSLSQALATEASQWHRMMTGGNLDSQGDPLPGVPL--PPSDPTRQETPPPRSPPVANSGS 731
GGN P PG P PP + + PPP P
Sbjct: 311 -------------------GGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQ 351
Query: 732 TGFSRRGSGRGGGPTPWGPAWDAGIAPPVLPQDEGAWP 769
G S+ S R P GP G P P G P
Sbjct: 352 GG-SKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNP 388
Score = 42.7 bits (99), Expect = 0.001
Identities = 40/144 (27%), Positives = 54/144 (37%), Gaps = 10/144 (6%)
Query: 497 PQKPPPHTEPDSPSPVLQGEESSERESLPESLELSSPRSPETDWGRPPGGDKDLASPHLG 556
PQ PPP +P P P G +S S P + P+ G PP K P G
Sbjct: 274 PQGPPPPGKPQGPPP-QGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG 332
Query: 557 LGSPR-VSRASSPEGRHLPSPQLGTKAPVARPRMSAQEQLERMRRNQECGRPFPRPTSPR 615
P+ P+G P PQ G+K+ AR + + N G P P +P+
Sbjct: 333 GNKPQGPPPPGKPQG---PPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQ 389
Query: 616 LLTLGRTLSPARRQPDVEQRPVVG 639
+ +P QP RP G
Sbjct: 390 -----QPQAPPAGQPQGPPRPPQG 408
Score = 42.0 bits (97), Expect = 0.002
Identities = 34/119 (28%), Positives = 47/119 (39%), Gaps = 17/119 (14%)
Query: 236 LSRPPSP-LSLPRPRSAPARRPPAPSGDTAPPARPHTPLSRIDVRP------------PL 282
+S+ SP L P+ AP + P G +PP +P P + +P P
Sbjct: 23 VSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP 82
Query: 283 DWGPQRQTLSRPPTPRRGPPSEAGGGKPPRSPQHWSQEPRTQAHSGSPTYLQLPPRPPG 341
G + PP +GPP + + PRSP Q P Q + Q PP PPG
Sbjct: 83 PQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQP----QGPPPPPG 137
Score = 32.0 bits (71), Expect = 2.3
Identities = 24/73 (32%), Positives = 28/73 (38%), Gaps = 7/73 (9%)
Query: 693 GGNLDSQGDPLPGVPL--PPSDPTRQETPP----PRSPPVANSGSTGFSRRGSGRGGGPT 746
GGN P PG P PP + + PP P+ PP S R G+ GP
Sbjct: 64 GGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRS-PRSPPGKPQGPP 122
Query: 747 PWGPAWDAGIAPP 759
P G G PP
Sbjct: 123 PQGGNQPQGPPPP 135
>gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2
preproprotein [Homo sapiens]
Length = 198
Score = 54.3 bits (129), Expect = 4e-07
Identities = 54/188 (28%), Positives = 76/188 (40%), Gaps = 40/188 (21%)
Query: 160 GQPRSPARPQPGEGPGGPGGPPEVSRGEEGRISESPEVTRLSRGRGRPRLLTPSPTTDLH 219
G P+ P+ PQ G P GP PP +G + P+ G+P+ P P D
Sbjct: 34 GNPQGPS-PQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPP---GKPQ--GPPPQGD-- 85
Query: 220 SGLQMRRARSPDLFTPLSRPPSPLSLPRPRSAPARRPPAPSGDTA----PPARPHTPLSR 275
++RSP PP P P+ + PP G+ PP +P P
Sbjct: 86 ------KSRSP------RSPPGKPQGPPPQGGKPQGPPPQGGNKPQGPPPPGKPQGP--- 130
Query: 276 IDVRPPLDWGPQRQTLSRPPTPRRGPPSEAGG---GKPPRSPQHWSQEPRTQAHSGSPTY 332
P G + Q+ PP +GPP + G G PP + + Q+P+ +G P
Sbjct: 131 -----PAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGN-PQQPQAPP-AGQP-- 181
Query: 333 LQLPPRPP 340
Q PPRPP
Sbjct: 182 -QGPPRPP 188
Score = 51.6 bits (122), Expect = 3e-06
Identities = 45/161 (27%), Positives = 62/161 (38%), Gaps = 22/161 (13%)
Query: 160 GQPRSPA-----RPQPGEGPGGPGGPPEVSRGEEGRISESPEVTRLSRGRGRPRLLTPSP 214
G+P+ P +PQ PG P GPP +G++ R SP G+P+ P P
Sbjct: 55 GKPQGPPPQGGNKPQGPPPPGKPQGPPP--QGDKSRSPRSPP--------GKPQ--GPPP 102
Query: 215 TTDLHSGLQMRRARSPDLFTPLSRPPSPLSLPRPRSAPARRPPAPSGDTAPPARPHTPLS 274
G + P P +P P + +S AR PP P P +
Sbjct: 103 QGGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGK-----PQGPPQQEGN 157
Query: 275 RIDVRPPLDWGPQRQTLSRPPTPRRGPPSEAGGGKPPRSPQ 315
PP G +Q + P +GPP GG+P R PQ
Sbjct: 158 NPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPPQ 198
Score = 42.0 bits (97), Expect = 0.002
Identities = 39/143 (27%), Positives = 55/143 (38%), Gaps = 20/143 (13%)
Query: 497 PQKPPPHTEPDSPSPVLQGEESSERESLPESLELSSPRSPETDWGRPPGGDKDLASPHLG 556
PQ PPP +P P P QG++S S P + P+ + P GG+K P G
Sbjct: 68 PQGPPPPGKPQGPPP--QGDKSRSPRSPPGKPQGPPPQGGKPQGPPPQGGNKPQGPPPPG 125
Query: 557 LGSPRVSRASSPEGRHLPSPQLGTKAPVARPRMSAQEQLERMRRNQECGRPFPRPTSPRL 616
P+G P Q G+K+ AR + + N G P P +P+
Sbjct: 126 ----------KPQG---PPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQ- 171
Query: 617 LTLGRTLSPARRQPDVEQRPVVG 639
+ +P QP RP G
Sbjct: 172 ----QPQAPPAGQPQGPPRPPQG 190
Score = 30.0 bits (66), Expect = 8.6
Identities = 23/67 (34%), Positives = 27/67 (40%), Gaps = 3/67 (4%)
Query: 693 GGNLDSQGDPLPGVPLPPSDPTRQETPPPRSPPVANSGSTGFSRRGSGRGGGPTPWGPAW 752
GGN QG P PG P P ++ RSPP G + G+ G P P G
Sbjct: 114 GGN-KPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPP--QQEGNNPQGPPPPAGGNP 170
Query: 753 DAGIAPP 759
APP
Sbjct: 171 QQPQAPP 177
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.133 0.412
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,592,725
Number of Sequences: 37866
Number of extensions: 3099645
Number of successful extensions: 30743
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 257
Number of HSP's successfully gapped in prelim test: 1901
Number of HSP's that attempted gapping in prelim test: 17938
Number of HSP's gapped (non-prelim): 11413
length of query: 779
length of database: 18,247,518
effective HSP length: 110
effective length of query: 669
effective length of database: 14,082,258
effective search space: 9421030602
effective search space used: 9421030602
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.