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Search of human proteins with 238624095
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|238624095 SET domain, bifurcated 2 isoform a [Homo sapiens]
(719 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|238624095 SET domain, bifurcated 2 isoform a [Homo sapiens] 1473 0.0
gi|238624099 SET domain, bifurcated 2 isoform b [Homo sapiens] 1442 0.0
gi|224177469 SET domain, bifurcated 1 isoform 2 [Homo sapiens] 241 2e-63
gi|224177467 SET domain, bifurcated 1 isoform 1 [Homo sapiens] 241 2e-63
gi|156142199 euchromatic histone-lysine N-methyltransferase 2 is... 92 2e-18
gi|156142197 euchromatic histone-lysine N-methyltransferase 2 is... 92 2e-18
gi|224465233 euchromatic histone-lysine N-methyltransferase 1 is... 92 2e-18
gi|194306650 SET domain and mariner transposase fusion [Homo sap... 75 2e-13
gi|4507321 suppressor of variegation 3-9 homolog 1 [Homo sapiens] 72 1e-12
gi|13375930 suppressor of variegation 3-9 homolog 2 [Homo sapiens] 66 1e-10
gi|210032580 SET domain containing 1B [Homo sapiens] 57 5e-08
gi|110349788 absent, small, or homeotic 1-like [Homo sapiens] 57 6e-08
gi|197313748 SET domain containing 2 [Homo sapiens] 57 8e-08
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 55 3e-07
gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [... 54 4e-07
gi|55741677 SET domain containing 1A [Homo sapiens] 54 5e-07
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 53 9e-07
gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo s... 53 9e-07
gi|19913358 Wolf-Hirschhorn syndrome candidate 1 protein isoform... 50 7e-06
gi|19913350 Wolf-Hirschhorn syndrome candidate 1 protein isoform... 50 7e-06
gi|19913348 Wolf-Hirschhorn syndrome candidate 1 protein isoform... 50 7e-06
gi|109633019 Wolf-Hirschhorn syndrome candidate 1 protein isofor... 50 7e-06
gi|19923202 enhancer of zeste homolog 1 [Homo sapiens] 50 1e-05
gi|27477095 nuclear receptor binding SET domain protein 1 isofor... 49 2e-05
gi|19923586 nuclear receptor binding SET domain protein 1 isofor... 49 2e-05
gi|23510384 enhancer of zeste 2 isoform b [Homo sapiens] 47 6e-05
gi|21361095 enhancer of zeste 2 isoform a [Homo sapiens] 47 6e-05
gi|13699811 WHSC1L1 protein isoform long [Homo sapiens] 46 1e-04
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo... 41 0.003
gi|91176325 bromodomain adjacent to zinc finger domain, 2A [Homo... 38 0.029
>gi|238624095 SET domain, bifurcated 2 isoform a [Homo sapiens]
Length = 719
Score = 1473 bits (3813), Expect = 0.0
Identities = 719/719 (100%), Positives = 719/719 (100%)
Query: 1 MGEKNGDAKTFWMELEDDGKVDFIFEQVQNVLQSLKQKIKDGSATNKEYIQAMILVNEAT 60
MGEKNGDAKTFWMELEDDGKVDFIFEQVQNVLQSLKQKIKDGSATNKEYIQAMILVNEAT
Sbjct: 1 MGEKNGDAKTFWMELEDDGKVDFIFEQVQNVLQSLKQKIKDGSATNKEYIQAMILVNEAT 60
Query: 61 IINSSTSIKGASQKEVNAQSSDPMPVTQKEQENKSNAFPSTSCENSFPEDCTFLTTENKE 120
IINSSTSIKGASQKEVNAQSSDPMPVTQKEQENKSNAFPSTSCENSFPEDCTFLTTENKE
Sbjct: 61 IINSSTSIKGASQKEVNAQSSDPMPVTQKEQENKSNAFPSTSCENSFPEDCTFLTTENKE 120
Query: 121 ILSLEDKVVDFREKDSSSNLSYQSHDCSGACLMKMPLNLKGENPLQLPIKCHFQRRHAKT 180
ILSLEDKVVDFREKDSSSNLSYQSHDCSGACLMKMPLNLKGENPLQLPIKCHFQRRHAKT
Sbjct: 121 ILSLEDKVVDFREKDSSSNLSYQSHDCSGACLMKMPLNLKGENPLQLPIKCHFQRRHAKT 180
Query: 181 NSHSSALHVSYKTPCGRSLRNVEEVFRYLLETECNFLFTDNFSFNTYVQLARNYPKQKEV 240
NSHSSALHVSYKTPCGRSLRNVEEVFRYLLETECNFLFTDNFSFNTYVQLARNYPKQKEV
Sbjct: 181 NSHSSALHVSYKTPCGRSLRNVEEVFRYLLETECNFLFTDNFSFNTYVQLARNYPKQKEV 240
Query: 241 VSDVDISNGVESVPISFCNEIDSRKLPQFKYRKTVWPRAYNLTNFSSMFTDSCDCSEGCI 300
VSDVDISNGVESVPISFCNEIDSRKLPQFKYRKTVWPRAYNLTNFSSMFTDSCDCSEGCI
Sbjct: 241 VSDVDISNGVESVPISFCNEIDSRKLPQFKYRKTVWPRAYNLTNFSSMFTDSCDCSEGCI 300
Query: 301 DITKCACLQLTARNAKTSPLSSDKITTGYKYKRLQRQIPTGIYECSLLCKCNRQLCQNRV 360
DITKCACLQLTARNAKTSPLSSDKITTGYKYKRLQRQIPTGIYECSLLCKCNRQLCQNRV
Sbjct: 301 DITKCACLQLTARNAKTSPLSSDKITTGYKYKRLQRQIPTGIYECSLLCKCNRQLCQNRV 360
Query: 361 VQHGPQVRLQVFKTEQKGWGVRCLDDIDRGTFVCIYSGRLLSRANTEKSYGIDENGRDEN 420
VQHGPQVRLQVFKTEQKGWGVRCLDDIDRGTFVCIYSGRLLSRANTEKSYGIDENGRDEN
Sbjct: 361 VQHGPQVRLQVFKTEQKGWGVRCLDDIDRGTFVCIYSGRLLSRANTEKSYGIDENGRDEN 420
Query: 421 TMKNIFSKKRKLEVACSDCEVEVLPLGLETHPRTAKTEKCPPKFSNNPKELTVETKYDNI 480
TMKNIFSKKRKLEVACSDCEVEVLPLGLETHPRTAKTEKCPPKFSNNPKELTVETKYDNI
Sbjct: 421 TMKNIFSKKRKLEVACSDCEVEVLPLGLETHPRTAKTEKCPPKFSNNPKELTVETKYDNI 480
Query: 481 SRIQYHSVIRDPESKTAIFQHNGKKMEFVSSESVTPEDNDGFKPPREHLNSKTKGAQKDS 540
SRIQYHSVIRDPESKTAIFQHNGKKMEFVSSESVTPEDNDGFKPPREHLNSKTKGAQKDS
Sbjct: 481 SRIQYHSVIRDPESKTAIFQHNGKKMEFVSSESVTPEDNDGFKPPREHLNSKTKGAQKDS 540
Query: 541 SSNHVDEFEDNLLIESDVIDITKYREETPPRSRCNQATTLDNQNIKKAIEVQIQKPQEGR 600
SSNHVDEFEDNLLIESDVIDITKYREETPPRSRCNQATTLDNQNIKKAIEVQIQKPQEGR
Sbjct: 541 SSNHVDEFEDNLLIESDVIDITKYREETPPRSRCNQATTLDNQNIKKAIEVQIQKPQEGR 600
Query: 601 STACQRQQVFCDEELLSETKNTSSDSLTKFNKGNVFLLDATKEGNVGRFLNHSCCPNLLV 660
STACQRQQVFCDEELLSETKNTSSDSLTKFNKGNVFLLDATKEGNVGRFLNHSCCPNLLV
Sbjct: 601 STACQRQQVFCDEELLSETKNTSSDSLTKFNKGNVFLLDATKEGNVGRFLNHSCCPNLLV 660
Query: 661 QNVFVETHNRNFPLVAFFTNRYVKARTELTWDYGYEAGTVPEKEIFCQCGVNKCRKKIL 719
QNVFVETHNRNFPLVAFFTNRYVKARTELTWDYGYEAGTVPEKEIFCQCGVNKCRKKIL
Sbjct: 661 QNVFVETHNRNFPLVAFFTNRYVKARTELTWDYGYEAGTVPEKEIFCQCGVNKCRKKIL 719
>gi|238624099 SET domain, bifurcated 2 isoform b [Homo sapiens]
Length = 707
Score = 1442 bits (3734), Expect = 0.0
Identities = 707/719 (98%), Positives = 707/719 (98%), Gaps = 12/719 (1%)
Query: 1 MGEKNGDAKTFWMELEDDGKVDFIFEQVQNVLQSLKQKIKDGSATNKEYIQAMILVNEAT 60
MGEKNGDAKTFWMELEDDGKVDFIFEQVQNVLQSLKQKIKDGSATNKEYIQAMILVNEAT
Sbjct: 1 MGEKNGDAKTFWMELEDDGKVDFIFEQVQNVLQSLKQKIKDGSATNKEYIQAMILVNEAT 60
Query: 61 IINSSTSIKGASQKEVNAQSSDPMPVTQKEQENKSNAFPSTSCENSFPEDCTFLTTENKE 120
IINSSTSIK DPMPVTQKEQENKSNAFPSTSCENSFPEDCTFLTTENKE
Sbjct: 61 IINSSTSIK------------DPMPVTQKEQENKSNAFPSTSCENSFPEDCTFLTTENKE 108
Query: 121 ILSLEDKVVDFREKDSSSNLSYQSHDCSGACLMKMPLNLKGENPLQLPIKCHFQRRHAKT 180
ILSLEDKVVDFREKDSSSNLSYQSHDCSGACLMKMPLNLKGENPLQLPIKCHFQRRHAKT
Sbjct: 109 ILSLEDKVVDFREKDSSSNLSYQSHDCSGACLMKMPLNLKGENPLQLPIKCHFQRRHAKT 168
Query: 181 NSHSSALHVSYKTPCGRSLRNVEEVFRYLLETECNFLFTDNFSFNTYVQLARNYPKQKEV 240
NSHSSALHVSYKTPCGRSLRNVEEVFRYLLETECNFLFTDNFSFNTYVQLARNYPKQKEV
Sbjct: 169 NSHSSALHVSYKTPCGRSLRNVEEVFRYLLETECNFLFTDNFSFNTYVQLARNYPKQKEV 228
Query: 241 VSDVDISNGVESVPISFCNEIDSRKLPQFKYRKTVWPRAYNLTNFSSMFTDSCDCSEGCI 300
VSDVDISNGVESVPISFCNEIDSRKLPQFKYRKTVWPRAYNLTNFSSMFTDSCDCSEGCI
Sbjct: 229 VSDVDISNGVESVPISFCNEIDSRKLPQFKYRKTVWPRAYNLTNFSSMFTDSCDCSEGCI 288
Query: 301 DITKCACLQLTARNAKTSPLSSDKITTGYKYKRLQRQIPTGIYECSLLCKCNRQLCQNRV 360
DITKCACLQLTARNAKTSPLSSDKITTGYKYKRLQRQIPTGIYECSLLCKCNRQLCQNRV
Sbjct: 289 DITKCACLQLTARNAKTSPLSSDKITTGYKYKRLQRQIPTGIYECSLLCKCNRQLCQNRV 348
Query: 361 VQHGPQVRLQVFKTEQKGWGVRCLDDIDRGTFVCIYSGRLLSRANTEKSYGIDENGRDEN 420
VQHGPQVRLQVFKTEQKGWGVRCLDDIDRGTFVCIYSGRLLSRANTEKSYGIDENGRDEN
Sbjct: 349 VQHGPQVRLQVFKTEQKGWGVRCLDDIDRGTFVCIYSGRLLSRANTEKSYGIDENGRDEN 408
Query: 421 TMKNIFSKKRKLEVACSDCEVEVLPLGLETHPRTAKTEKCPPKFSNNPKELTVETKYDNI 480
TMKNIFSKKRKLEVACSDCEVEVLPLGLETHPRTAKTEKCPPKFSNNPKELTVETKYDNI
Sbjct: 409 TMKNIFSKKRKLEVACSDCEVEVLPLGLETHPRTAKTEKCPPKFSNNPKELTVETKYDNI 468
Query: 481 SRIQYHSVIRDPESKTAIFQHNGKKMEFVSSESVTPEDNDGFKPPREHLNSKTKGAQKDS 540
SRIQYHSVIRDPESKTAIFQHNGKKMEFVSSESVTPEDNDGFKPPREHLNSKTKGAQKDS
Sbjct: 469 SRIQYHSVIRDPESKTAIFQHNGKKMEFVSSESVTPEDNDGFKPPREHLNSKTKGAQKDS 528
Query: 541 SSNHVDEFEDNLLIESDVIDITKYREETPPRSRCNQATTLDNQNIKKAIEVQIQKPQEGR 600
SSNHVDEFEDNLLIESDVIDITKYREETPPRSRCNQATTLDNQNIKKAIEVQIQKPQEGR
Sbjct: 529 SSNHVDEFEDNLLIESDVIDITKYREETPPRSRCNQATTLDNQNIKKAIEVQIQKPQEGR 588
Query: 601 STACQRQQVFCDEELLSETKNTSSDSLTKFNKGNVFLLDATKEGNVGRFLNHSCCPNLLV 660
STACQRQQVFCDEELLSETKNTSSDSLTKFNKGNVFLLDATKEGNVGRFLNHSCCPNLLV
Sbjct: 589 STACQRQQVFCDEELLSETKNTSSDSLTKFNKGNVFLLDATKEGNVGRFLNHSCCPNLLV 648
Query: 661 QNVFVETHNRNFPLVAFFTNRYVKARTELTWDYGYEAGTVPEKEIFCQCGVNKCRKKIL 719
QNVFVETHNRNFPLVAFFTNRYVKARTELTWDYGYEAGTVPEKEIFCQCGVNKCRKKIL
Sbjct: 649 QNVFVETHNRNFPLVAFFTNRYVKARTELTWDYGYEAGTVPEKEIFCQCGVNKCRKKIL 707
>gi|224177469 SET domain, bifurcated 1 isoform 2 [Homo sapiens]
Length = 1290
Score = 241 bits (614), Expect = 2e-63
Identities = 121/268 (45%), Positives = 165/268 (61%), Gaps = 5/268 (1%)
Query: 140 LSYQSHDCSGACLMKM-PLN---LKGENPLQLPIKCHFQRRHAKTN-SHSSALHVSYKTP 194
L Y H CS CL ++ P+ +G+NPL +P+ F+R A+ + HV YKTP
Sbjct: 571 LFYLPHVCSYTCLSRVRPMRNEQYRGKNPLLVPLLYDFRRMTARRRVNRKMGFHVIYKTP 630
Query: 195 CGRSLRNVEEVFRYLLETECNFLFTDNFSFNTYVQLARNYPKQKEVVSDVDISNGVESVP 254
CG LR ++E+ RYL ET C+FLF + F + YV + R + K +DI+ G E VP
Sbjct: 631 CGLCLRTMQEIERYLFETGCDFLFLEMFCLDPYVLVDRKFQPYKPFYYILDITYGKEDVP 690
Query: 255 ISFCNEIDSRKLPQFKYRKTVWPRAYNLTNFSSMFTDSCDCSEGCIDITKCACLQLTARN 314
+S NEID+ PQ Y K P N F CDC +GC D +KCAC QLT +
Sbjct: 691 LSCVNEIDTTPPPQVAYSKERIPGKGVFINTGPEFLVGCDCKDGCRDKSKCACHQLTIQA 750
Query: 315 AKTSPLSSDKITTGYKYKRLQRQIPTGIYECSLLCKCNRQLCQNRVVQHGPQVRLQVFKT 374
+P +GY+YKRL+ +PTG+YEC+ CKC+ +C NR+VQHG QVRLQ+FKT
Sbjct: 751 TACTPGGQINPNSGYQYKRLEECLPTGVYECNKRCKCDPNMCTNRLVQHGLQVRLQLFKT 810
Query: 375 EQKGWGVRCLDDIDRGTFVCIYSGRLLS 402
+ KGWG+RCLDDI +G+FVCIY+G++L+
Sbjct: 811 QNKGWGIRCLDDIAKGSFVCIYAGKILT 838
Score = 112 bits (279), Expect = 2e-24
Identities = 49/84 (58%), Positives = 65/84 (77%), Gaps = 1/84 (1%)
Query: 636 FLLDATKEGNVGRFLNHSCCPNLLVQNVFVETHNRNFPLVAFFTNRYVKARTELTWDYGY 695
+++DA EGN+GR+LNHSC PNL VQNVFV+TH+ FP VAFF ++ ++A TELTWDY Y
Sbjct: 1208 YIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASK-IRAGTELTWDYNY 1266
Query: 696 EAGTVPEKEIFCQCGVNKCRKKIL 719
E G+V KE+ C CG +CR ++L
Sbjct: 1267 EVGSVEGKELLCCCGAIECRGRLL 1290
>gi|224177467 SET domain, bifurcated 1 isoform 1 [Homo sapiens]
Length = 1291
Score = 241 bits (614), Expect = 2e-63
Identities = 121/268 (45%), Positives = 165/268 (61%), Gaps = 5/268 (1%)
Query: 140 LSYQSHDCSGACLMKM-PLN---LKGENPLQLPIKCHFQRRHAKTN-SHSSALHVSYKTP 194
L Y H CS CL ++ P+ +G+NPL +P+ F+R A+ + HV YKTP
Sbjct: 571 LFYLPHVCSYTCLSRVRPMRNEQYRGKNPLLVPLLYDFRRMTARRRVNRKMGFHVIYKTP 630
Query: 195 CGRSLRNVEEVFRYLLETECNFLFTDNFSFNTYVQLARNYPKQKEVVSDVDISNGVESVP 254
CG LR ++E+ RYL ET C+FLF + F + YV + R + K +DI+ G E VP
Sbjct: 631 CGLCLRTMQEIERYLFETGCDFLFLEMFCLDPYVLVDRKFQPYKPFYYILDITYGKEDVP 690
Query: 255 ISFCNEIDSRKLPQFKYRKTVWPRAYNLTNFSSMFTDSCDCSEGCIDITKCACLQLTARN 314
+S NEID+ PQ Y K P N F CDC +GC D +KCAC QLT +
Sbjct: 691 LSCVNEIDTTPPPQVAYSKERIPGKGVFINTGPEFLVGCDCKDGCRDKSKCACHQLTIQA 750
Query: 315 AKTSPLSSDKITTGYKYKRLQRQIPTGIYECSLLCKCNRQLCQNRVVQHGPQVRLQVFKT 374
+P +GY+YKRL+ +PTG+YEC+ CKC+ +C NR+VQHG QVRLQ+FKT
Sbjct: 751 TACTPGGQINPNSGYQYKRLEECLPTGVYECNKRCKCDPNMCTNRLVQHGLQVRLQLFKT 810
Query: 375 EQKGWGVRCLDDIDRGTFVCIYSGRLLS 402
+ KGWG+RCLDDI +G+FVCIY+G++L+
Sbjct: 811 QNKGWGIRCLDDIAKGSFVCIYAGKILT 838
Score = 115 bits (289), Expect = 1e-25
Identities = 49/84 (58%), Positives = 65/84 (77%)
Query: 636 FLLDATKEGNVGRFLNHSCCPNLLVQNVFVETHNRNFPLVAFFTNRYVKARTELTWDYGY 695
+++DA EGN+GR+LNHSC PNL VQNVFV+TH+ FP VAFF ++ ++A TELTWDY Y
Sbjct: 1208 YIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGTELTWDYNY 1267
Query: 696 EAGTVPEKEIFCQCGVNKCRKKIL 719
E G+V KE+ C CG +CR ++L
Sbjct: 1268 EVGSVEGKELLCCCGAIECRGRLL 1291
>gi|156142199 euchromatic histone-lysine N-methyltransferase 2 isoform
b [Homo sapiens]
Length = 1176
Score = 92.0 bits (227), Expect = 2e-18
Identities = 61/179 (34%), Positives = 89/179 (49%), Gaps = 15/179 (8%)
Query: 245 DISNGVESVPISFCNEIDSRKLPQ-FKYRKTVWPRAYNLTNFSSMFTDSCDCSEGCIDIT 303
D++ G E+VPI N +D P+ +KY + + + C C + C +
Sbjct: 891 DVARGYENVPIPCVNGVDGEPCPEDYKYISENCETSTMNIDRNITHLQHCTCVDDCSS-S 949
Query: 304 KCACLQLTARNAKTSPLSSDKITTGYKYKRLQRQIPTGIYECSLLCKCNRQLCQNRVVQH 363
C C QL+ R DK G + + P I+EC+ C C R C+NRVVQ
Sbjct: 950 NCLCGQLSIR------CWYDK--DGRLLQEFNKIEPPLIFECNQACSCWRN-CKNRVVQS 1000
Query: 364 GPQVRLQVFKTEQKGWGVRCLDDIDRGTFVCIYSGRLLSRANT----EKSYGIDENGRD 418
G +VRLQ+++T + GWGVR L I +GTF+C Y G L+S A + SY D + +D
Sbjct: 1001 GIKVRLQLYRTAKMGWGVRALQTIPQGTFICEYVGELISDAEADVREDDSYLFDLDNKD 1059
Score = 77.0 bits (188), Expect = 6e-14
Identities = 52/167 (31%), Positives = 82/167 (49%), Gaps = 18/167 (10%)
Query: 567 ETPPRSRCNQATTL----DNQNIKKAIEVQIQKPQEG------RSTACQRQQVFCDE--- 613
E P CNQA + N+ ++ I+V++Q + R+ Q F E
Sbjct: 976 EPPLIFECNQACSCWRNCKNRVVQSGIKVRLQLYRTAKMGWGVRALQTIPQGTFICEYVG 1035
Query: 614 ELLSETK-NTSSDSLTKFN----KGNVFLLDATKEGNVGRFLNHSCCPNLLVQNVFVETH 668
EL+S+ + + D F+ G V+ +DA GN+ RF+NH C PN++ VF+
Sbjct: 1036 ELISDAEADVREDDSYLFDLDNKDGEVYCIDARYYGNISRFINHLCDPNIIPVRVFMLHQ 1095
Query: 669 NRNFPLVAFFTNRYVKARTELTWDYGYEAGTVPEKEIFCQCGVNKCR 715
+ FP +AFF++R ++ EL +DYG + K CQCG KC+
Sbjct: 1096 DLRFPRIAFFSSRDIRTGEELGFDYGDRFWDIKSKYFTCQCGSEKCK 1142
>gi|156142197 euchromatic histone-lysine N-methyltransferase 2 isoform
a [Homo sapiens]
Length = 1210
Score = 92.0 bits (227), Expect = 2e-18
Identities = 61/179 (34%), Positives = 89/179 (49%), Gaps = 15/179 (8%)
Query: 245 DISNGVESVPISFCNEIDSRKLPQ-FKYRKTVWPRAYNLTNFSSMFTDSCDCSEGCIDIT 303
D++ G E+VPI N +D P+ +KY + + + C C + C +
Sbjct: 925 DVARGYENVPIPCVNGVDGEPCPEDYKYISENCETSTMNIDRNITHLQHCTCVDDCSS-S 983
Query: 304 KCACLQLTARNAKTSPLSSDKITTGYKYKRLQRQIPTGIYECSLLCKCNRQLCQNRVVQH 363
C C QL+ R DK G + + P I+EC+ C C R C+NRVVQ
Sbjct: 984 NCLCGQLSIR------CWYDK--DGRLLQEFNKIEPPLIFECNQACSCWRN-CKNRVVQS 1034
Query: 364 GPQVRLQVFKTEQKGWGVRCLDDIDRGTFVCIYSGRLLSRANT----EKSYGIDENGRD 418
G +VRLQ+++T + GWGVR L I +GTF+C Y G L+S A + SY D + +D
Sbjct: 1035 GIKVRLQLYRTAKMGWGVRALQTIPQGTFICEYVGELISDAEADVREDDSYLFDLDNKD 1093
Score = 77.0 bits (188), Expect = 6e-14
Identities = 52/167 (31%), Positives = 82/167 (49%), Gaps = 18/167 (10%)
Query: 567 ETPPRSRCNQATTL----DNQNIKKAIEVQIQKPQEG------RSTACQRQQVFCDE--- 613
E P CNQA + N+ ++ I+V++Q + R+ Q F E
Sbjct: 1010 EPPLIFECNQACSCWRNCKNRVVQSGIKVRLQLYRTAKMGWGVRALQTIPQGTFICEYVG 1069
Query: 614 ELLSETK-NTSSDSLTKFN----KGNVFLLDATKEGNVGRFLNHSCCPNLLVQNVFVETH 668
EL+S+ + + D F+ G V+ +DA GN+ RF+NH C PN++ VF+
Sbjct: 1070 ELISDAEADVREDDSYLFDLDNKDGEVYCIDARYYGNISRFINHLCDPNIIPVRVFMLHQ 1129
Query: 669 NRNFPLVAFFTNRYVKARTELTWDYGYEAGTVPEKEIFCQCGVNKCR 715
+ FP +AFF++R ++ EL +DYG + K CQCG KC+
Sbjct: 1130 DLRFPRIAFFSSRDIRTGEELGFDYGDRFWDIKSKYFTCQCGSEKCK 1176
>gi|224465233 euchromatic histone-lysine N-methyltransferase 1 isoform
1 [Homo sapiens]
Length = 1298
Score = 91.7 bits (226), Expect = 2e-18
Identities = 66/193 (34%), Positives = 90/193 (46%), Gaps = 15/193 (7%)
Query: 231 ARNYPKQKEVVSDVDISNGVESVPISFCNEIDSRKLPQ-FKYRKTVWPRAYNLTNFSSMF 289
A + P E + DI+ G E +PI N +DS P +KY + + +
Sbjct: 999 APDRPSPVERIVSRDIARGYERIPIPCVNAVDSEPCPSNYKYVSQNCVTSPMNIDRNITH 1058
Query: 290 TDSCDCSEGCIDITKCACLQLTARNAKTSPLSSDKITTGYKYKRLQRQIPTGIYECSLLC 349
C C + C + C C QL+ R DK G P I+EC+ C
Sbjct: 1059 LQYCVCIDDCSS-SNCMCGQLSMR------CWYDK--DGRLLPEFNMAEPPLIFECNHAC 1109
Query: 350 KCNRQLCQNRVVQHGPQVRLQVFKTEQKGWGVRCLDDIDRGTFVCIYSGRLLSRANT--- 406
C R C+NRVVQ+G + RLQ+++T GWGVR L DI GTFVC Y G L+S +
Sbjct: 1110 SCWRN-CRNRVVQNGLRARLQLYRTRDMGWGVRSLQDIPPGTFVCEYVGELISDSEADVR 1168
Query: 407 -EKSYGIDENGRD 418
E SY D + +D
Sbjct: 1169 EEDSYLFDLDNKD 1181
Score = 75.1 bits (183), Expect = 2e-13
Identities = 35/83 (42%), Positives = 49/83 (59%)
Query: 633 GNVFLLDATKEGNVGRFLNHSCCPNLLVQNVFVETHNRNFPLVAFFTNRYVKARTELTWD 692
G V+ +DA GNV RF+NH C PNL+ VF+ + FP +AFF+ R ++A +L +D
Sbjct: 1182 GEVYCIDARFYGNVSRFINHHCEPNLVPVRVFMAHQDLRFPRIAFFSTRLIEAGEQLGFD 1241
Query: 693 YGYEAGTVPEKEIFCQCGVNKCR 715
YG + K C+CG KCR
Sbjct: 1242 YGERFWDIKGKLFSCRCGSPKCR 1264
>gi|194306650 SET domain and mariner transposase fusion [Homo
sapiens]
Length = 684
Score = 75.1 bits (183), Expect = 2e-13
Identities = 41/104 (39%), Positives = 60/104 (57%), Gaps = 10/104 (9%)
Query: 305 CACLQLTARNAKTSPLSSDKITTGYKYKRLQRQIPTGIYECSLLCKCNRQLCQNRVVQHG 364
C+CL+ S L I +G KY ++EC++LC+C+ C+NRVVQ G
Sbjct: 87 CSCLRHGENYDDNSCLRD--IGSGGKYAE-------PVFECNVLCRCSDH-CRNRVVQKG 136
Query: 365 PQVRLQVFKTEQKGWGVRCLDDIDRGTFVCIYSGRLLSRANTEK 408
Q QVFKT +KGWG+R L+ I +G FVC Y+G +L + ++
Sbjct: 137 LQFHFQVFKTHKKGWGLRTLEFIPKGRFVCEYAGEVLGFSEVQR 180
Score = 48.9 bits (115), Expect = 2e-05
Identities = 34/88 (38%), Positives = 45/88 (51%), Gaps = 14/88 (15%)
Query: 638 LDATKEGNVGRFLNHSCCPNLLVQNVFVETHNRNFPLVAFFTNRYVKARTELTWDYG--Y 695
+D T GN+GRFLNHSC PNLL+ V +++ P +A F + + EL++DY Y
Sbjct: 210 VDPTYIGNIGRFLNHSCEPNLLMIPVRIDS---MVPKLALFAAKDIVPEEELSYDYSGRY 266
Query: 696 EAGTVPE-KEIF--------CQCGVNKC 714
TV E KE C CG C
Sbjct: 267 LNLTVSEDKERLDHGKLRKPCYCGAKSC 294
>gi|4507321 suppressor of variegation 3-9 homolog 1 [Homo sapiens]
Length = 412
Score = 72.4 bits (176), Expect = 1e-12
Identities = 38/104 (36%), Positives = 53/104 (50%), Gaps = 21/104 (20%)
Query: 634 NVFLLDATKEGNVGRFLNHSCCPNLLVQNVFVETHNRNFPLVAFFTNRYVKARTELTWDY 693
+V+ +DA GN+ F+NHSC PNL V NVF++ + P +AFF R ++A ELT+DY
Sbjct: 306 DVYTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIRAGEELTFDY 365
Query: 694 GYEAGTV-------------------PEK--EIFCQCGVNKCRK 716
+ V P+K I C+CG CRK
Sbjct: 366 NMQVDPVDMESTRMDSNFGLAGLPGSPKKRVRIECKCGTESCRK 409
Score = 58.5 bits (140), Expect = 2e-08
Identities = 31/77 (40%), Positives = 47/77 (61%), Gaps = 4/77 (5%)
Query: 333 RLQRQIPTGIYECSLLCKCNRQLCQNRVVQHGPQVRLQVFKTEQ-KGWGVRCLDDIDRGT 391
RL+ +P IYEC+ C+C C NRVVQ G + L +F+T+ +GWGVR L+ I + +
Sbjct: 212 RLRAGLP--IYECNSRCRCGYD-CPNRVVQKGIRYDLCIFRTDDGRGWGVRTLEKIRKNS 268
Query: 392 FVCIYSGRLLSRANTEK 408
FV Y G +++ E+
Sbjct: 269 FVMEYVGEIITSEEAER 285
>gi|13375930 suppressor of variegation 3-9 homolog 2 [Homo sapiens]
Length = 350
Score = 66.2 bits (160), Expect = 1e-10
Identities = 35/92 (38%), Positives = 49/92 (53%), Gaps = 12/92 (13%)
Query: 636 FLLDATKEGNVGRFLNHSCCPNLLVQNVFVETHNRNFPLVAFFTNRYVKARTELTWDYGY 695
F +DA + GNV F+NHSC PNL V NVF++ + P +A F+ R + A ELT+DY
Sbjct: 255 FTVDAARYGNVSHFVNHSCDPNLQVFNVFIDNLDTRLPRIALFSTRTINAGEELTFDYQM 314
Query: 696 E-AGTVPEKEI-----------FCQCGVNKCR 715
+ +G + I C+CG CR
Sbjct: 315 KGSGDISSDSIDHSPAKKRVRTVCKCGAVTCR 346
Score = 58.9 bits (141), Expect = 2e-08
Identities = 33/80 (41%), Positives = 46/80 (57%), Gaps = 4/80 (5%)
Query: 332 KRLQRQIPTG--IYECSLLCKCNRQLCQNRVVQHGPQVRLQVFKTEQ-KGWGVRCLDDID 388
K Q +IP G IYEC+ C+C C NR+VQ G Q L +F+T +GWGV+ L I
Sbjct: 154 KNQQIKIPPGTPIYECNSRCQCGPD-CPNRIVQKGTQYSLCIFRTSNGRGWGVKTLVKIK 212
Query: 389 RGTFVCIYSGRLLSRANTEK 408
R +FV Y G +++ E+
Sbjct: 213 RMSFVMEYVGEVITSEEAER 232
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 57.4 bits (137), Expect = 5e-08
Identities = 26/79 (32%), Positives = 45/79 (56%), Gaps = 7/79 (8%)
Query: 637 LLDATKEGNVGRFLNHSCCPNLLVQNVFVETHNRNFPLVAFFTNRYVKARTELTWDYGYE 696
++DATK GN RF+NHSC PN + + VE+ + + ++ +++ E+T+DY +
Sbjct: 1848 IIDATKCGNFARFINHSCNPNCYAKVITVESQKK----IVIYSKQHINVNEEITYDYKF- 1902
Query: 697 AGTVPEKEIFCQCGVNKCR 715
+ + +I C CG CR
Sbjct: 1903 --PIEDVKIPCLCGSENCR 1919
>gi|110349788 absent, small, or homeotic 1-like [Homo sapiens]
Length = 2964
Score = 57.0 bits (136), Expect = 6e-08
Identities = 31/85 (36%), Positives = 47/85 (55%), Gaps = 5/85 (5%)
Query: 631 NKGNVFLLDATKEGNVGRFLNHSCCPNLLVQNVFVETHNRNFPLVAFFTNRYVKARTELT 690
N + ++D+ + GN RF+NHSC PN +Q V R + + + + A TELT
Sbjct: 2197 NLDSGMVIDSYRMGNEARFINHSCDPNCEMQKWSVNGVYR----IGLYALKDMPAGTELT 2252
Query: 691 WDYGYEAGTVPEKEIFCQCGVNKCR 715
+DY + + V EK+ C+CG KCR
Sbjct: 2253 YDYNFHSFNV-EKQQLCKCGFEKCR 2276
Score = 48.1 bits (113), Expect = 3e-05
Identities = 22/60 (36%), Positives = 33/60 (55%), Gaps = 1/60 (1%)
Query: 344 ECSL-LCKCNRQLCQNRVVQHGPQVRLQVFKTEQKGWGVRCLDDIDRGTFVCIYSGRLLS 402
ECS C C Q C R+ +H L+ F+ E+KGWG+R + + G F+ Y G ++S
Sbjct: 2116 ECSPNTCPCGEQCCNQRIQRHEWVQCLERFRAEEKGWGIRTKEPLKAGQFIIEYLGEVVS 2175
>gi|197313748 SET domain containing 2 [Homo sapiens]
Length = 2564
Score = 56.6 bits (135), Expect = 8e-08
Identities = 33/80 (41%), Positives = 45/80 (56%), Gaps = 8/80 (10%)
Query: 637 LLDATKEGNVGRFLNHSCCPNLLVQNVFVETHNRNFPLVAFFTNRYVKARTELTWDYGYE 696
++DAT++GN RF+NHSC PN Q V R V FFT + V + +ELT+DY ++
Sbjct: 1614 IIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLR----VGFFTTKLVPSGSELTFDYQFQ 1669
Query: 697 A-GTVPEKEIFCQCGVNKCR 715
G +K C CG CR
Sbjct: 1670 RYGKEAQK---CFCGSANCR 1686
Score = 49.3 bits (116), Expect = 1e-05
Identities = 36/111 (32%), Positives = 50/111 (45%), Gaps = 19/111 (17%)
Query: 318 SPLSSDKITTGYKYKRLQRQIPTG--------IYECSLLCKCNRQLCQNRVVQHGPQVRL 369
+PLS D+ R Q +I G + ECS C N C NR Q +
Sbjct: 1502 TPLSKDE--------RAQGEIACGEDCLNRLLMIECSSRCP-NGDYCSNRRFQRKQHADV 1552
Query: 370 QVFKTEQKGWGVRCLDDIDRGTFVCIYSGRLLSRANTEKSYGIDENGRDEN 420
+V TE+KGWG+R D+ TFV Y G +L + E + E R++N
Sbjct: 1553 EVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLD--HKEFKARVKEYARNKN 1601
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 54.7 bits (130), Expect = 3e-07
Identities = 29/87 (33%), Positives = 42/87 (48%), Gaps = 5/87 (5%)
Query: 630 FNKGNVFLLDATKEGNVGRFLNHSCCPNLLVQNVFVETHNRNFPLVAFFTNRYVKARTEL 689
F + ++DAT GN RF+NHSC PN + + VE + F R + EL
Sbjct: 2631 FRMDDFDVVDATMHGNAARFINHSCEPNCFSRVIHVEGQKH----IVIFALRRILRGEEL 2686
Query: 690 TWDYGYEAGTVPEKEIFCQCGVNKCRK 716
T+DY + K + C CG +CR+
Sbjct: 2687 TYDYKFPIEDASNK-LPCNCGAKRCRR 2712
>gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [Homo
sapiens]
Length = 3969
Score = 54.3 bits (129), Expect = 4e-07
Identities = 28/80 (35%), Positives = 40/80 (50%), Gaps = 5/80 (6%)
Query: 637 LLDATKEGNVGRFLNHSCCPNLLVQNVFVETHNRNFPLVAFFTNRYVKARTELTWDYGYE 696
++DAT GN RF+NHSC PN + + ++ + F R + ELT+DY +
Sbjct: 3892 VVDATMHGNAARFINHSCEPNCYSRVINIDGQKH----IVIFAMRKIYRGEELTYDYKFP 3947
Query: 697 AGTVPEKEIFCQCGVNKCRK 716
K + C CG KCRK
Sbjct: 3948 IEDASNK-LPCNCGAKKCRK 3966
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 53.9 bits (128), Expect = 5e-07
Identities = 24/79 (30%), Positives = 44/79 (55%), Gaps = 7/79 (8%)
Query: 637 LLDATKEGNVGRFLNHSCCPNLLVQNVFVETHNRNFPLVAFFTNRYVKARTELTWDYGYE 696
++DATK GN+ RF+NH C PN + + +E+ + + ++ + + E+T+DY +
Sbjct: 1632 IIDATKCGNLARFINHCCTPNCYAKVITIESQKK----IVIYSKQPIGVDEEITYDYKF- 1686
Query: 697 AGTVPEKEIFCQCGVNKCR 715
+ + +I C CG CR
Sbjct: 1687 --PLEDNKIPCLCGTESCR 1703
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 53.1 bits (126), Expect = 9e-07
Identities = 32/111 (28%), Positives = 54/111 (48%), Gaps = 8/111 (7%)
Query: 606 RQQVFCDEELLSETKNTSSDSLTKFNKGNVFLLDATKEGNVGRFLNHSCCPNLLVQNVFV 665
R +V E + E +N + F N ++DAT G R++NHSC PN + + V
Sbjct: 5432 RNEVANRREKIYEEQNRG---IYMFRINNEHVIDATLTGGPARYINHSCAPNCVAEVVTF 5488
Query: 666 ETHNRNFPLVAFFTNRYVKARTELTWDYGYEAGTVPEKEIFCQCGVNKCRK 716
+ ++ + ++R + ELT+DY ++ + +I C CG CRK
Sbjct: 5489 DKEDK----IIIISSRRIPKGEELTYDYQFDFED-DQHKIPCHCGAWNCRK 5534
>gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo
sapiens]
Length = 4911
Score = 53.1 bits (126), Expect = 9e-07
Identities = 33/111 (29%), Positives = 56/111 (50%), Gaps = 8/111 (7%)
Query: 606 RQQVFCDEELLSETKNTSSDSLTKFNKGNVFLLDATKEGNVGRFLNHSCCPNLLVQNVFV 665
R +V +E L E++N + F N ++DAT G R++NHSC PN + + V
Sbjct: 4806 RNEVANRKEKLYESQNRG---VYMFRMDNDHVIDATLTGGPARYINHSCAPNCVAEVVTF 4862
Query: 666 ETHNRNFPLVAFFTNRYVKARTELTWDYGYEAGTVPEKEIFCQCGVNKCRK 716
E ++ + ++R ++ EL +DY ++ + +I C CG CRK
Sbjct: 4863 ERGHK----IIISSSRRIQKGEELCYDYKFDFED-DQHKIPCHCGAVNCRK 4908
>gi|19913358 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
[Homo sapiens]
Length = 1365
Score = 50.1 bits (118), Expect = 7e-06
Identities = 31/106 (29%), Positives = 51/106 (48%), Gaps = 9/106 (8%)
Query: 612 DEELLSETKNTSSDSLTKFNKGNVF---LLDATKEGNVGRFLNHSCCPNLLVQNVFVETH 668
+EE ++ K+ + +T F + ++DA +GN RF+NHSC PN V
Sbjct: 1099 EEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGD 1158
Query: 669 NRNFPLVAFFTNRYVKARTELTWDYGYEAGTVPEKEIFCQCGVNKC 714
R V F + A TELT++Y + + ++ C+CG + C
Sbjct: 1159 TR----VGLFAVCDIPAGTELTFNYNLDC--LGNEKTVCRCGASNC 1198
Score = 40.0 bits (92), Expect = 0.008
Identities = 36/138 (26%), Positives = 56/138 (40%), Gaps = 26/138 (18%)
Query: 264 RKLPQFKYRKTVWPRAYNLTNFSSMFTDSCDCSEGCIDITKCACLQLTARNAKTSPLSSD 323
RK P +K+ K P + + + D SE I KC C +D
Sbjct: 986 RKPPPYKHIKVNKP-------YGKVQIYTADISE----IPKCNCKP------------TD 1022
Query: 324 KITTGYKYKRLQRQIPTGIYECSLLCKCNRQLCQNRVVQHGPQVRLQVFKTEQKGWGVRC 383
+ G+ + L R + ++EC + CQN+ ++ KT+ KGWG+
Sbjct: 1023 ENPCGFDSECLNRML---MFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVA 1079
Query: 384 LDDIDRGTFVCIYSGRLL 401
DI +G FV Y G L+
Sbjct: 1080 KRDIRKGEFVNEYVGELI 1097
>gi|19913350 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
[Homo sapiens]
Length = 1365
Score = 50.1 bits (118), Expect = 7e-06
Identities = 31/106 (29%), Positives = 51/106 (48%), Gaps = 9/106 (8%)
Query: 612 DEELLSETKNTSSDSLTKFNKGNVF---LLDATKEGNVGRFLNHSCCPNLLVQNVFVETH 668
+EE ++ K+ + +T F + ++DA +GN RF+NHSC PN V
Sbjct: 1099 EEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGD 1158
Query: 669 NRNFPLVAFFTNRYVKARTELTWDYGYEAGTVPEKEIFCQCGVNKC 714
R V F + A TELT++Y + + ++ C+CG + C
Sbjct: 1159 TR----VGLFAVCDIPAGTELTFNYNLDC--LGNEKTVCRCGASNC 1198
Score = 40.0 bits (92), Expect = 0.008
Identities = 36/138 (26%), Positives = 56/138 (40%), Gaps = 26/138 (18%)
Query: 264 RKLPQFKYRKTVWPRAYNLTNFSSMFTDSCDCSEGCIDITKCACLQLTARNAKTSPLSSD 323
RK P +K+ K P + + + D SE I KC C +D
Sbjct: 986 RKPPPYKHIKVNKP-------YGKVQIYTADISE----IPKCNCKP------------TD 1022
Query: 324 KITTGYKYKRLQRQIPTGIYECSLLCKCNRQLCQNRVVQHGPQVRLQVFKTEQKGWGVRC 383
+ G+ + L R + ++EC + CQN+ ++ KT+ KGWG+
Sbjct: 1023 ENPCGFDSECLNRML---MFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVA 1079
Query: 384 LDDIDRGTFVCIYSGRLL 401
DI +G FV Y G L+
Sbjct: 1080 KRDIRKGEFVNEYVGELI 1097
>gi|19913348 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
[Homo sapiens]
Length = 1365
Score = 50.1 bits (118), Expect = 7e-06
Identities = 31/106 (29%), Positives = 51/106 (48%), Gaps = 9/106 (8%)
Query: 612 DEELLSETKNTSSDSLTKFNKGNVF---LLDATKEGNVGRFLNHSCCPNLLVQNVFVETH 668
+EE ++ K+ + +T F + ++DA +GN RF+NHSC PN V
Sbjct: 1099 EEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGD 1158
Query: 669 NRNFPLVAFFTNRYVKARTELTWDYGYEAGTVPEKEIFCQCGVNKC 714
R V F + A TELT++Y + + ++ C+CG + C
Sbjct: 1159 TR----VGLFAVCDIPAGTELTFNYNLDC--LGNEKTVCRCGASNC 1198
Score = 40.0 bits (92), Expect = 0.008
Identities = 36/138 (26%), Positives = 56/138 (40%), Gaps = 26/138 (18%)
Query: 264 RKLPQFKYRKTVWPRAYNLTNFSSMFTDSCDCSEGCIDITKCACLQLTARNAKTSPLSSD 323
RK P +K+ K P + + + D SE I KC C +D
Sbjct: 986 RKPPPYKHIKVNKP-------YGKVQIYTADISE----IPKCNCKP------------TD 1022
Query: 324 KITTGYKYKRLQRQIPTGIYECSLLCKCNRQLCQNRVVQHGPQVRLQVFKTEQKGWGVRC 383
+ G+ + L R + ++EC + CQN+ ++ KT+ KGWG+
Sbjct: 1023 ENPCGFDSECLNRML---MFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVA 1079
Query: 384 LDDIDRGTFVCIYSGRLL 401
DI +G FV Y G L+
Sbjct: 1080 KRDIRKGEFVNEYVGELI 1097
>gi|109633019 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
[Homo sapiens]
Length = 1365
Score = 50.1 bits (118), Expect = 7e-06
Identities = 31/106 (29%), Positives = 51/106 (48%), Gaps = 9/106 (8%)
Query: 612 DEELLSETKNTSSDSLTKFNKGNVF---LLDATKEGNVGRFLNHSCCPNLLVQNVFVETH 668
+EE ++ K+ + +T F + ++DA +GN RF+NHSC PN V
Sbjct: 1099 EEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGD 1158
Query: 669 NRNFPLVAFFTNRYVKARTELTWDYGYEAGTVPEKEIFCQCGVNKC 714
R V F + A TELT++Y + + ++ C+CG + C
Sbjct: 1159 TR----VGLFAVCDIPAGTELTFNYNLDC--LGNEKTVCRCGASNC 1198
Score = 40.0 bits (92), Expect = 0.008
Identities = 36/138 (26%), Positives = 56/138 (40%), Gaps = 26/138 (18%)
Query: 264 RKLPQFKYRKTVWPRAYNLTNFSSMFTDSCDCSEGCIDITKCACLQLTARNAKTSPLSSD 323
RK P +K+ K P + + + D SE I KC C +D
Sbjct: 986 RKPPPYKHIKVNKP-------YGKVQIYTADISE----IPKCNCKP------------TD 1022
Query: 324 KITTGYKYKRLQRQIPTGIYECSLLCKCNRQLCQNRVVQHGPQVRLQVFKTEQKGWGVRC 383
+ G+ + L R + ++EC + CQN+ ++ KT+ KGWG+
Sbjct: 1023 ENPCGFDSECLNRML---MFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVA 1079
Query: 384 LDDIDRGTFVCIYSGRLL 401
DI +G FV Y G L+
Sbjct: 1080 KRDIRKGEFVNEYVGELI 1097
>gi|19923202 enhancer of zeste homolog 1 [Homo sapiens]
Length = 747
Score = 49.7 bits (117), Expect = 1e-05
Identities = 27/66 (40%), Positives = 37/66 (56%), Gaps = 4/66 (6%)
Query: 630 FNKGNVFLLDATKEGNVGRFLNHSCCPNLLVQNVFVETHNRNFPLVAFFTNRYVKARTEL 689
FN N F++DAT++GN RF NHS PN + V V +R + F R ++A EL
Sbjct: 668 FNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHR----IGIFAKRAIQAGEEL 723
Query: 690 TWDYGY 695
+DY Y
Sbjct: 724 FFDYRY 729
Score = 33.9 bits (76), Expect = 0.54
Identities = 14/58 (24%), Positives = 28/58 (48%)
Query: 351 CNRQLCQNRVVQHGPQVRLQVFKTEQKGWGVRCLDDIDRGTFVCIYSGRLLSRANTEK 408
C C+N +Q G + L + ++ GWG + + + F+ Y G L+S+ ++
Sbjct: 597 CKVVSCKNCSIQRGLKKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADR 654
>gi|27477095 nuclear receptor binding SET domain protein 1 isoform a
[Homo sapiens]
Length = 2427
Score = 48.9 bits (115), Expect = 2e-05
Identities = 28/78 (35%), Positives = 38/78 (48%), Gaps = 6/78 (7%)
Query: 637 LLDATKEGNVGRFLNHSCCPNLLVQNVFVETHNRNFPLVAFFTNRYVKARTELTWDYGYE 696
++DA +GN RF+NH C PN Q V R V F +KA TELT++Y E
Sbjct: 1737 IIDAGPKGNYARFMNHCCQPNCETQKWSVNGDTR----VGLFALSDIKAGTELTFNYNLE 1792
Query: 697 AGTVPEKEIFCQCGVNKC 714
+ + C+CG C
Sbjct: 1793 C--LGNGKTVCKCGAPNC 1808
Score = 43.9 bits (102), Expect = 5e-04
Identities = 22/61 (36%), Positives = 34/61 (55%), Gaps = 2/61 (3%)
Query: 342 IYECS-LLCKCNRQLCQNRVVQHGPQVRLQVFKTEQKGWGVRCLDDIDRGTFVCIYSGRL 400
+YEC +C + CQN+ +++F+T Q+GWG+R DI +G FV Y G L
Sbjct: 1648 LYECHPTVCPAGGR-CQNQCFSKRQYPEVEIFRTLQRGWGLRTKTDIKKGEFVNEYVGEL 1706
Query: 401 L 401
+
Sbjct: 1707 I 1707
>gi|19923586 nuclear receptor binding SET domain protein 1 isoform b
[Homo sapiens]
Length = 2696
Score = 48.9 bits (115), Expect = 2e-05
Identities = 28/78 (35%), Positives = 38/78 (48%), Gaps = 6/78 (7%)
Query: 637 LLDATKEGNVGRFLNHSCCPNLLVQNVFVETHNRNFPLVAFFTNRYVKARTELTWDYGYE 696
++DA +GN RF+NH C PN Q V R V F +KA TELT++Y E
Sbjct: 2006 IIDAGPKGNYARFMNHCCQPNCETQKWSVNGDTR----VGLFALSDIKAGTELTFNYNLE 2061
Query: 697 AGTVPEKEIFCQCGVNKC 714
+ + C+CG C
Sbjct: 2062 C--LGNGKTVCKCGAPNC 2077
Score = 43.9 bits (102), Expect = 5e-04
Identities = 22/61 (36%), Positives = 34/61 (55%), Gaps = 2/61 (3%)
Query: 342 IYECS-LLCKCNRQLCQNRVVQHGPQVRLQVFKTEQKGWGVRCLDDIDRGTFVCIYSGRL 400
+YEC +C + CQN+ +++F+T Q+GWG+R DI +G FV Y G L
Sbjct: 1917 LYECHPTVCPAGGR-CQNQCFSKRQYPEVEIFRTLQRGWGLRTKTDIKKGEFVNEYVGEL 1975
Query: 401 L 401
+
Sbjct: 1976 I 1976
>gi|23510384 enhancer of zeste 2 isoform b [Homo sapiens]
Length = 707
Score = 47.0 bits (110), Expect = 6e-05
Identities = 25/66 (37%), Positives = 36/66 (54%), Gaps = 4/66 (6%)
Query: 630 FNKGNVFLLDATKEGNVGRFLNHSCCPNLLVQNVFVETHNRNFPLVAFFTNRYVKARTEL 689
FN N F++DAT++GN RF NHS PN + + V +R + F R ++ EL
Sbjct: 628 FNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHR----IGIFAKRAIQTGEEL 683
Query: 690 TWDYGY 695
+DY Y
Sbjct: 684 FFDYRY 689
Score = 35.4 bits (80), Expect = 0.19
Identities = 13/53 (24%), Positives = 28/53 (52%)
Query: 356 CQNRVVQHGPQVRLQVFKTEQKGWGVRCLDDIDRGTFVCIYSGRLLSRANTEK 408
C+N +Q G + L + ++ GWG+ D + + F+ Y G ++S+ ++
Sbjct: 562 CKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADR 614
>gi|21361095 enhancer of zeste 2 isoform a [Homo sapiens]
Length = 751
Score = 47.0 bits (110), Expect = 6e-05
Identities = 25/66 (37%), Positives = 36/66 (54%), Gaps = 4/66 (6%)
Query: 630 FNKGNVFLLDATKEGNVGRFLNHSCCPNLLVQNVFVETHNRNFPLVAFFTNRYVKARTEL 689
FN N F++DAT++GN RF NHS PN + + V +R + F R ++ EL
Sbjct: 672 FNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHR----IGIFAKRAIQTGEEL 727
Query: 690 TWDYGY 695
+DY Y
Sbjct: 728 FFDYRY 733
Score = 35.4 bits (80), Expect = 0.19
Identities = 13/53 (24%), Positives = 28/53 (52%)
Query: 356 CQNRVVQHGPQVRLQVFKTEQKGWGVRCLDDIDRGTFVCIYSGRLLSRANTEK 408
C+N +Q G + L + ++ GWG+ D + + F+ Y G ++S+ ++
Sbjct: 606 CKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADR 658
>gi|13699811 WHSC1L1 protein isoform long [Homo sapiens]
Length = 1437
Score = 45.8 bits (107), Expect = 1e-04
Identities = 33/106 (31%), Positives = 46/106 (43%), Gaps = 9/106 (8%)
Query: 612 DEELLSETKNTSSDSLTKFNKGNVF---LLDATKEGNVGRFLNHSCCPNLLVQNVFVETH 668
+EE K +S+T F V ++DA +GN RF+NHSC PN Q V
Sbjct: 1181 EEECRLRIKRAHENSVTNFYMLTVTKDRIIDAGPKGNYSRFMNHSCNPNCETQKWTVNGD 1240
Query: 669 NRNFPLVAFFTNRYVKARTELTWDYGYEAGTVPEKEIFCQCGVNKC 714
R V F + A ELT++Y + + C CG + C
Sbjct: 1241 VR----VGLFALCDIPAGMELTFNYNLDC--LGNGRTECHCGADNC 1280
Score = 38.5 bits (88), Expect = 0.022
Identities = 28/105 (26%), Positives = 46/105 (43%), Gaps = 7/105 (6%)
Query: 322 SDKITTGYKYKRLQRQIPTGIYECSLLCKCNRQLCQNRVVQHGPQVRLQVFKTEQKGWGV 381
+D+ G + + L R + YEC CQN+ ++ KTE++GWG+
Sbjct: 1103 ADENPCGLESECLNRMLQ---YECHPQVCPAGDRCQNQCFTKRLYPDAEIIKTERRGWGL 1159
Query: 382 RCLDDIDRGTFVCIYSGRLLSRANTEKSYGIDENGRDENTMKNIF 426
R I +G FV Y G L+ E+ + EN++ N +
Sbjct: 1160 RTKRSIKKGEFVNEYVGELID----EEECRLRIKRAHENSVTNFY 1200
>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
sapiens]
Length = 2168
Score = 41.2 bits (95), Expect = 0.003
Identities = 30/100 (30%), Positives = 46/100 (46%), Gaps = 6/100 (6%)
Query: 136 SSSNLSYQSHDCSGACLMKMPLNLKGENPLQLPIKCHFQRRHAKTNSHSSAL-HVSYKTP 194
SSS L+ H SG + + E L++P++ +QR N V+Y P
Sbjct: 721 SSSTLTSSPH--SGTSKRR---RVTDERELRIPLEYGWQRETRIRNFGGRLQGEVAYYAP 775
Query: 195 CGRSLRNVEEVFRYLLETECNFLFTDNFSFNTYVQLARNY 234
CG+ LR EV +YL + DNFSF+ +++ Y
Sbjct: 776 CGKKLRQYPEVIKYLSRNGIMDISRDNFSFSAKIRVGDFY 815
>gi|91176325 bromodomain adjacent to zinc finger domain, 2A [Homo
sapiens]
Length = 1905
Score = 38.1 bits (87), Expect = 0.029
Identities = 47/207 (22%), Positives = 80/207 (38%), Gaps = 25/207 (12%)
Query: 64 SSTSIKGASQKEVNAQSSDPMPVTQKE-----QENKSNAFPSTSCENSFPEDCTFLTTEN 118
+ST + A V+ SS +P E A P TS +FP + N
Sbjct: 457 ASTVVSPAVFSVVSPASSAVLPAVSLEVPLTASVTSPKASPVTSPAAAFPT----ASPAN 512
Query: 119 KEILSLEDKVVDFREKDSSSNLSYQSHDCSGACLMKMPLNLKGENPLQLPIKCHFQRR-H 177
K++ S + D E + S D M + ++LP++ ++R
Sbjct: 513 KDVSSFLETTADVEEITGEGLTASGSGDV-------MRRRIATPEEVRLPLQHGWRREVR 565
Query: 178 AKTNSHSSALHVSYKTPCGRSLRNVEEVFRYLLETECNFLFTDNFSFNTYVQLARNYPKQ 237
K SH Y PCG+ ++ EV +YL + + ++FSF+ + +
Sbjct: 566 IKKGSHRWQGETWYYGPCGKRMKQFPEVIKYLSRNVVHSVRREHFSFSPRMPVG------ 619
Query: 238 KEVVSDVDISNGVESVPISFCNEIDSR 264
+ + D G++ V +S EI SR
Sbjct: 620 -DFFEERDTPEGLQWVQLS-AEEIPSR 644
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.131 0.386
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,672,113
Number of Sequences: 37866
Number of extensions: 1222818
Number of successful extensions: 3420
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 34
Number of HSP's that attempted gapping in prelim test: 3328
Number of HSP's gapped (non-prelim): 108
length of query: 719
length of database: 18,247,518
effective HSP length: 110
effective length of query: 609
effective length of database: 14,082,258
effective search space: 8576095122
effective search space used: 8576095122
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.