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Search of human proteins with 238550100
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|238550100 transmembrane channel-like 7 isoform b [Homo
sapiens]
(613 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|238550100 transmembrane channel-like 7 isoform b [Homo sapiens] 1234 0.0
gi|238550098 transmembrane channel-like 7 isoform a [Homo sapiens] 1234 0.0
gi|21389589 transmembrane channel-like 4 isoform 2 [Homo sapiens] 432 e-121
gi|223718080 transmembrane channel-like 4 isoform 1 [Homo sapiens] 432 e-121
gi|23943900 transmembrane channel-like 8 [Homo sapiens] 363 e-100
gi|21071070 transmembrane channel-like 1 [Homo sapiens] 229 6e-60
gi|157426860 transmembrane channel-like 5 isoform a [Homo sapiens] 228 1e-59
gi|31377679 transmembrane channel-like 5 isoform c [Homo sapiens] 228 1e-59
gi|94536852 transmembrane cochlear-expressed protein 2 [Homo sap... 213 5e-55
gi|157426862 transmembrane channel-like 5 isoform b [Homo sapiens] 202 1e-51
gi|187608784 transmembrane channel-like 6 [Homo sapiens] 194 3e-49
gi|187608791 transmembrane channel-like 6 [Homo sapiens] 194 3e-49
gi|122937502 transmembrane channel-like 3 [Homo sapiens] 146 5e-35
gi|18677729 relaxin/insulin-like family peptide receptor 2 [Homo... 38 0.024
gi|83700231 cytotoxic T-lymphocyte-associated protein 4 isoform ... 33 0.59
gi|21361212 cytotoxic T-lymphocyte-associated protein 4 isoform ... 33 0.59
gi|106067657 luteinizing hormone/choriogonadotropin receptor pre... 32 1.7
gi|24431958 solute carrier family 16, member 7 [Homo sapiens] 30 5.0
gi|21536376 ATP-binding cassette, sub-family A member 1 [Homo sa... 30 6.5
gi|4503175 chemokine (C-X-C motif) receptor 4 isoform b [Homo sa... 30 8.5
gi|56790927 chemokine (C-X-C motif) receptor 4 isoform a [Homo s... 30 8.5
>gi|238550100 transmembrane channel-like 7 isoform b [Homo sapiens]
Length = 613
Score = 1234 bits (3193), Expect = 0.0
Identities = 613/613 (100%), Positives = 613/613 (100%)
Query: 1 MKYLSEWDQWKRYSSKSWKRFLEKAREMTTHLELWREDIRSIEGKFGTGIQSYFSFLRFL 60
MKYLSEWDQWKRYSSKSWKRFLEKAREMTTHLELWREDIRSIEGKFGTGIQSYFSFLRFL
Sbjct: 1 MKYLSEWDQWKRYSSKSWKRFLEKAREMTTHLELWREDIRSIEGKFGTGIQSYFSFLRFL 60
Query: 61 VLLNLVIFLIIFMLVLLPVLLTKYKITNSSFVLIPFKDMDKQCTVYPVSSSGLIYFYSYI 120
VLLNLVIFLIIFMLVLLPVLLTKYKITNSSFVLIPFKDMDKQCTVYPVSSSGLIYFYSYI
Sbjct: 61 VLLNLVIFLIIFMLVLLPVLLTKYKITNSSFVLIPFKDMDKQCTVYPVSSSGLIYFYSYI 120
Query: 121 IDLLSGTGFLEETSLFYGHYTIDGVKFQNFTYDLPLAYLLSTIASLALSLLWIVKRSVEG 180
IDLLSGTGFLEETSLFYGHYTIDGVKFQNFTYDLPLAYLLSTIASLALSLLWIVKRSVEG
Sbjct: 121 IDLLSGTGFLEETSLFYGHYTIDGVKFQNFTYDLPLAYLLSTIASLALSLLWIVKRSVEG 180
Query: 181 FKINLIRSEEHFQSYCNKIFAGWDFCITNRSMADLKHSSLRYELRADLEEERMRQKIAER 240
FKINLIRSEEHFQSYCNKIFAGWDFCITNRSMADLKHSSLRYELRADLEEERMRQKIAER
Sbjct: 181 FKINLIRSEEHFQSYCNKIFAGWDFCITNRSMADLKHSSLRYELRADLEEERMRQKIAER 240
Query: 241 TSEETIRIYSLRLFLNCIVLAVLGACFYAIYVATVFSQEHMKKEIDKMVFGENLFILYLP 300
TSEETIRIYSLRLFLNCIVLAVLGACFYAIYVATVFSQEHMKKEIDKMVFGENLFILYLP
Sbjct: 241 TSEETIRIYSLRLFLNCIVLAVLGACFYAIYVATVFSQEHMKKEIDKMVFGENLFILYLP 300
Query: 301 SIVITLANFITPMIFAKIIRYEDYSPGFEIRLTILRCVFMRLATICVLVFTLGSKITSCD 360
SIVITLANFITPMIFAKIIRYEDYSPGFEIRLTILRCVFMRLATICVLVFTLGSKITSCD
Sbjct: 301 SIVITLANFITPMIFAKIIRYEDYSPGFEIRLTILRCVFMRLATICVLVFTLGSKITSCD 360
Query: 361 DDTCDLCGYNQKLYPCWETQVGQEMYKLMIFDFIIILAVTLFVDFPRKLLVTYCSSCKLI 420
DDTCDLCGYNQKLYPCWETQVGQEMYKLMIFDFIIILAVTLFVDFPRKLLVTYCSSCKLI
Sbjct: 361 DDTCDLCGYNQKLYPCWETQVGQEMYKLMIFDFIIILAVTLFVDFPRKLLVTYCSSCKLI 420
Query: 421 QCWGQQEFAIPDNVLGIVYGQTICWIGAFFSPLLPAIATLKFIIIFYVKEWSLLYTCRPS 480
QCWGQQEFAIPDNVLGIVYGQTICWIGAFFSPLLPAIATLKFIIIFYVKEWSLLYTCRPS
Sbjct: 421 QCWGQQEFAIPDNVLGIVYGQTICWIGAFFSPLLPAIATLKFIIIFYVKEWSLLYTCRPS 480
Query: 481 PRPFRASNSNFFFLLVLLIGLCLAIIPLTISISRIPSSKACGPFTNFNTTWEVIPKTVST 540
PRPFRASNSNFFFLLVLLIGLCLAIIPLTISISRIPSSKACGPFTNFNTTWEVIPKTVST
Sbjct: 481 PRPFRASNSNFFFLLVLLIGLCLAIIPLTISISRIPSSKACGPFTNFNTTWEVIPKTVST 540
Query: 541 FPSSLQSFIHGVTSEAFAVPFFMIICLIMFYFIALAGAHKRVVIQLREQLSLESRDKCYL 600
FPSSLQSFIHGVTSEAFAVPFFMIICLIMFYFIALAGAHKRVVIQLREQLSLESRDKCYL
Sbjct: 541 FPSSLQSFIHGVTSEAFAVPFFMIICLIMFYFIALAGAHKRVVIQLREQLSLESRDKCYL 600
Query: 601 IQKLTEAQRDMRN 613
IQKLTEAQRDMRN
Sbjct: 601 IQKLTEAQRDMRN 613
>gi|238550098 transmembrane channel-like 7 isoform a [Homo sapiens]
Length = 723
Score = 1234 bits (3193), Expect = 0.0
Identities = 613/613 (100%), Positives = 613/613 (100%)
Query: 1 MKYLSEWDQWKRYSSKSWKRFLEKAREMTTHLELWREDIRSIEGKFGTGIQSYFSFLRFL 60
MKYLSEWDQWKRYSSKSWKRFLEKAREMTTHLELWREDIRSIEGKFGTGIQSYFSFLRFL
Sbjct: 111 MKYLSEWDQWKRYSSKSWKRFLEKAREMTTHLELWREDIRSIEGKFGTGIQSYFSFLRFL 170
Query: 61 VLLNLVIFLIIFMLVLLPVLLTKYKITNSSFVLIPFKDMDKQCTVYPVSSSGLIYFYSYI 120
VLLNLVIFLIIFMLVLLPVLLTKYKITNSSFVLIPFKDMDKQCTVYPVSSSGLIYFYSYI
Sbjct: 171 VLLNLVIFLIIFMLVLLPVLLTKYKITNSSFVLIPFKDMDKQCTVYPVSSSGLIYFYSYI 230
Query: 121 IDLLSGTGFLEETSLFYGHYTIDGVKFQNFTYDLPLAYLLSTIASLALSLLWIVKRSVEG 180
IDLLSGTGFLEETSLFYGHYTIDGVKFQNFTYDLPLAYLLSTIASLALSLLWIVKRSVEG
Sbjct: 231 IDLLSGTGFLEETSLFYGHYTIDGVKFQNFTYDLPLAYLLSTIASLALSLLWIVKRSVEG 290
Query: 181 FKINLIRSEEHFQSYCNKIFAGWDFCITNRSMADLKHSSLRYELRADLEEERMRQKIAER 240
FKINLIRSEEHFQSYCNKIFAGWDFCITNRSMADLKHSSLRYELRADLEEERMRQKIAER
Sbjct: 291 FKINLIRSEEHFQSYCNKIFAGWDFCITNRSMADLKHSSLRYELRADLEEERMRQKIAER 350
Query: 241 TSEETIRIYSLRLFLNCIVLAVLGACFYAIYVATVFSQEHMKKEIDKMVFGENLFILYLP 300
TSEETIRIYSLRLFLNCIVLAVLGACFYAIYVATVFSQEHMKKEIDKMVFGENLFILYLP
Sbjct: 351 TSEETIRIYSLRLFLNCIVLAVLGACFYAIYVATVFSQEHMKKEIDKMVFGENLFILYLP 410
Query: 301 SIVITLANFITPMIFAKIIRYEDYSPGFEIRLTILRCVFMRLATICVLVFTLGSKITSCD 360
SIVITLANFITPMIFAKIIRYEDYSPGFEIRLTILRCVFMRLATICVLVFTLGSKITSCD
Sbjct: 411 SIVITLANFITPMIFAKIIRYEDYSPGFEIRLTILRCVFMRLATICVLVFTLGSKITSCD 470
Query: 361 DDTCDLCGYNQKLYPCWETQVGQEMYKLMIFDFIIILAVTLFVDFPRKLLVTYCSSCKLI 420
DDTCDLCGYNQKLYPCWETQVGQEMYKLMIFDFIIILAVTLFVDFPRKLLVTYCSSCKLI
Sbjct: 471 DDTCDLCGYNQKLYPCWETQVGQEMYKLMIFDFIIILAVTLFVDFPRKLLVTYCSSCKLI 530
Query: 421 QCWGQQEFAIPDNVLGIVYGQTICWIGAFFSPLLPAIATLKFIIIFYVKEWSLLYTCRPS 480
QCWGQQEFAIPDNVLGIVYGQTICWIGAFFSPLLPAIATLKFIIIFYVKEWSLLYTCRPS
Sbjct: 531 QCWGQQEFAIPDNVLGIVYGQTICWIGAFFSPLLPAIATLKFIIIFYVKEWSLLYTCRPS 590
Query: 481 PRPFRASNSNFFFLLVLLIGLCLAIIPLTISISRIPSSKACGPFTNFNTTWEVIPKTVST 540
PRPFRASNSNFFFLLVLLIGLCLAIIPLTISISRIPSSKACGPFTNFNTTWEVIPKTVST
Sbjct: 591 PRPFRASNSNFFFLLVLLIGLCLAIIPLTISISRIPSSKACGPFTNFNTTWEVIPKTVST 650
Query: 541 FPSSLQSFIHGVTSEAFAVPFFMIICLIMFYFIALAGAHKRVVIQLREQLSLESRDKCYL 600
FPSSLQSFIHGVTSEAFAVPFFMIICLIMFYFIALAGAHKRVVIQLREQLSLESRDKCYL
Sbjct: 651 FPSSLQSFIHGVTSEAFAVPFFMIICLIMFYFIALAGAHKRVVIQLREQLSLESRDKCYL 710
Query: 601 IQKLTEAQRDMRN 613
IQKLTEAQRDMRN
Sbjct: 711 IQKLTEAQRDMRN 723
>gi|21389589 transmembrane channel-like 4 isoform 2 [Homo sapiens]
Length = 706
Score = 432 bits (1112), Expect = e-121
Identities = 237/599 (39%), Positives = 359/599 (59%), Gaps = 22/599 (3%)
Query: 8 DQWKRYSSKSWKRFLEKAREMTTHLELWREDIRSIEGKFGTGIQSYFSFLRFLVLLNLVI 67
D+W R +S EK +E L+ W ++ I G+FG G +SYFS LRFL+LLN++
Sbjct: 116 DRWARLLRRS----KEKTKEGLRSLQPWAWTLKRIGGQFGAGTESYFSLLRFLLLLNVLA 171
Query: 68 FLIIFMLVLLPVLLTKYKITNSSFVLIPFKDMDKQCTVYPVSSSGLIYFYSYIIDLLSGT 127
+++ + LLP L + P D+ C Y S GL+ F + + +LLSG
Sbjct: 172 SVLMACMTLLPTWL------GGAPPGPPGPDISSPCGSYNPHSQGLVTFATQLFNLLSGE 225
Query: 128 GFLEETSLFYGHYTIDGVKFQNFTYDLPLAYLLSTIASLALSLLWIVKRSVEGFKINLIR 187
G+LE + LFYG Y L + YL A + LL I+ RSV G K L+
Sbjct: 226 GYLEWSPLFYGFYPPRP--------RLAVTYLCWAFAVGLICLLLILHRSVSGLKQTLLA 277
Query: 188 SEEHFQSYCNKIFAGWDFCITNRSMADLKHSSLRYELRADLEEERMRQKIAERTSEETIR 247
E SY +++F+ WDF + L+ + YEL+ +LEE +R++ A RT + R
Sbjct: 278 ESEALTSYSHRVFSAWDFGLCGDVHVRLRQRIILYELKVELEETVVRRQAAVRTLGQQAR 337
Query: 248 IYSLRLFLNCIVLAVLGACFYAIYVATVFSQEHMKKEIDKMVFGENLFILYLPSIVITLA 307
++ +R+ LN +V+A+LGA FY +Y AT + E + + + + L + YLPSI I
Sbjct: 338 VWLVRVLLNLLVVALLGAAFYGVYWATGCTVELQEMPLVQELPLLKLGVNYLPSIFIAGV 397
Query: 308 NFITPMIFAKIIRYEDYSPGFEIRLTILRCVFMRLATICVLVFTLGSKITSCDD---DTC 364
NF+ P +F I E Y+ +I +LR VF+RLA++ VL+F+L ++IT D + C
Sbjct: 398 NFVLPPVFKLIAPLEGYTRSRQIVFILLRTVFLRLASLVVLLFSLWNQITCGGDSEAEDC 457
Query: 365 DLCGYNQKLYPCWETQVGQEMYKLMIFDFIIILAVTLFVDFPRKLLVTYCSSCKLIQCWG 424
CGYN K PCWET +GQEMYKL++FD + +LAV L + FPRKLL C L + G
Sbjct: 458 KTCGYNYKQLPCWETVLGQEMYKLLLFDLLTVLAVALLIQFPRKLLCGLCPGA-LGRLAG 516
Query: 425 QQEFAIPDNVLGIVYGQTICWIGAFFSPLLPAIATLKFIIIFYVKEWSLLYTCRPSPRPF 484
QEF +PD VLG++Y QT+ W+G+FF PLLP + T+KF+++FY+K+ +L TC P+ R F
Sbjct: 517 TQEFQVPDEVLGLIYAQTVVWVGSFFCPLLPLLNTVKFLLLFYLKKLTLFSTCSPAARTF 576
Query: 485 RASNSNFFFLLVLLIGLCLAIIPLTISISRIPSSKACGPFTNFNTTWEVIPKTVSTFPSS 544
RAS +NFFF LVLL+GL ++ +PL SI IP SK CGPF ++ W IP+++S+ P +
Sbjct: 577 RASAANFFFPLVLLLGLAISSVPLLYSIFLIPPSKLCGPFRGQSSIWAQIPESISSLPET 636
Query: 545 LQSFIHGVTSEAFAVPFFMIICLIMFYFIALAGAHKRVVIQLREQLSLESRDKCYLIQK 603
Q+F+ + ++AFAVP +I ++M Y +ALA ++ R++ +L+ Q E+++K +L ++
Sbjct: 637 TQNFLFFLGTQAFAVPLLLISSILMAYTVALANSYGRLISELKRQRQTEAQNKVFLARR 695
>gi|223718080 transmembrane channel-like 4 isoform 1 [Homo sapiens]
Length = 712
Score = 432 bits (1112), Expect = e-121
Identities = 237/599 (39%), Positives = 359/599 (59%), Gaps = 22/599 (3%)
Query: 8 DQWKRYSSKSWKRFLEKAREMTTHLELWREDIRSIEGKFGTGIQSYFSFLRFLVLLNLVI 67
D+W R +S EK +E L+ W ++ I G+FG G +SYFS LRFL+LLN++
Sbjct: 122 DRWARLLRRS----KEKTKEGLRSLQPWAWTLKRIGGQFGAGTESYFSLLRFLLLLNVLA 177
Query: 68 FLIIFMLVLLPVLLTKYKITNSSFVLIPFKDMDKQCTVYPVSSSGLIYFYSYIIDLLSGT 127
+++ + LLP L + P D+ C Y S GL+ F + + +LLSG
Sbjct: 178 SVLMACMTLLPTWL------GGAPPGPPGPDISSPCGSYNPHSQGLVTFATQLFNLLSGE 231
Query: 128 GFLEETSLFYGHYTIDGVKFQNFTYDLPLAYLLSTIASLALSLLWIVKRSVEGFKINLIR 187
G+LE + LFYG Y L + YL A + LL I+ RSV G K L+
Sbjct: 232 GYLEWSPLFYGFYPPRP--------RLAVTYLCWAFAVGLICLLLILHRSVSGLKQTLLA 283
Query: 188 SEEHFQSYCNKIFAGWDFCITNRSMADLKHSSLRYELRADLEEERMRQKIAERTSEETIR 247
E SY +++F+ WDF + L+ + YEL+ +LEE +R++ A RT + R
Sbjct: 284 ESEALTSYSHRVFSAWDFGLCGDVHVRLRQRIILYELKVELEETVVRRQAAVRTLGQQAR 343
Query: 248 IYSLRLFLNCIVLAVLGACFYAIYVATVFSQEHMKKEIDKMVFGENLFILYLPSIVITLA 307
++ +R+ LN +V+A+LGA FY +Y AT + E + + + + L + YLPSI I
Sbjct: 344 VWLVRVLLNLLVVALLGAAFYGVYWATGCTVELQEMPLVQELPLLKLGVNYLPSIFIAGV 403
Query: 308 NFITPMIFAKIIRYEDYSPGFEIRLTILRCVFMRLATICVLVFTLGSKITSCDD---DTC 364
NF+ P +F I E Y+ +I +LR VF+RLA++ VL+F+L ++IT D + C
Sbjct: 404 NFVLPPVFKLIAPLEGYTRSRQIVFILLRTVFLRLASLVVLLFSLWNQITCGGDSEAEDC 463
Query: 365 DLCGYNQKLYPCWETQVGQEMYKLMIFDFIIILAVTLFVDFPRKLLVTYCSSCKLIQCWG 424
CGYN K PCWET +GQEMYKL++FD + +LAV L + FPRKLL C L + G
Sbjct: 464 KTCGYNYKQLPCWETVLGQEMYKLLLFDLLTVLAVALLIQFPRKLLCGLCPGA-LGRLAG 522
Query: 425 QQEFAIPDNVLGIVYGQTICWIGAFFSPLLPAIATLKFIIIFYVKEWSLLYTCRPSPRPF 484
QEF +PD VLG++Y QT+ W+G+FF PLLP + T+KF+++FY+K+ +L TC P+ R F
Sbjct: 523 TQEFQVPDEVLGLIYAQTVVWVGSFFCPLLPLLNTVKFLLLFYLKKLTLFSTCSPAARTF 582
Query: 485 RASNSNFFFLLVLLIGLCLAIIPLTISISRIPSSKACGPFTNFNTTWEVIPKTVSTFPSS 544
RAS +NFFF LVLL+GL ++ +PL SI IP SK CGPF ++ W IP+++S+ P +
Sbjct: 583 RASAANFFFPLVLLLGLAISSVPLLYSIFLIPPSKLCGPFRGQSSIWAQIPESISSLPET 642
Query: 545 LQSFIHGVTSEAFAVPFFMIICLIMFYFIALAGAHKRVVIQLREQLSLESRDKCYLIQK 603
Q+F+ + ++AFAVP +I ++M Y +ALA ++ R++ +L+ Q E+++K +L ++
Sbjct: 643 TQNFLFFLGTQAFAVPLLLISSILMAYTVALANSYGRLISELKRQRQTEAQNKVFLARR 701
>gi|23943900 transmembrane channel-like 8 [Homo sapiens]
Length = 726
Score = 363 bits (932), Expect = e-100
Identities = 215/607 (35%), Positives = 341/607 (56%), Gaps = 30/607 (4%)
Query: 7 WDQWKRYSSKSWKRFLEKAREMTTHLELWREDIRSIEGKFGTGIQSYFSFLRFLVLLNLV 66
W +W+R +R E A+ + L LW + I G FGTGI+SYF+FLRFL+LLNL+
Sbjct: 63 WQRWQRRRQTVERRLREAAQRLARGLGLWEGALYEIGGLFGTGIRSYFTFLRFLLLLNLL 122
Query: 67 IFLIIFMLVLLPVLLTKYKITNSSFVLIPFKDMDKQCTVYPVSSSGLIYFYSYIIDLLSG 126
L+ VLLP++ + P ++ QC S G++ F++ + +L+G
Sbjct: 123 SLLLTASFVLLPLVWLRPPDPG------PTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTG 176
Query: 127 TGFLEETSLFYGHYTIDGVKFQNFTYDLPLAYLLSTIASLALSLLWIVKRSVEGFKINLI 186
F T LFYG Y + + Y + LAYLLS +A L L ++R V+G +
Sbjct: 177 RAFTN-TYLFYGAYRVGPES--SSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTL 233
Query: 187 RSEEHFQSYCNKIFAGWDFCITNRSMADLKHSSLRYELRADLEEERMRQKIAERTSEETI 246
+ + K+F+ WDFCI + A +K + E + +LEE R Q + ++T +T
Sbjct: 234 LGQGYQAPLSAKVFSSWDFCIRVQEAATIKKHEISNEFKVELEEGRRFQLMQQQTRAQTA 293
Query: 247 RIYSLRLFLNCIVLAVLGACFYAIYVATVFSQEHMKKEIDKMVFGENLFIL--YLPSIVI 304
L +N + ++ AI+ AT +SQ++ + E+LF+L YLP VI
Sbjct: 294 CRLLSYLRVNVLNGLLVVGAISAIFWATKYSQDNKE---------ESLFLLLQYLPPGVI 344
Query: 305 TLANFITPMIFAKIIRYEDYSPGFEIRLTILRCVFMRLATICVLVFTLGSKITSC--DDD 362
L NF+ P++F +++ E+Y P E+ LT++ CV ++LA++ + +LG I D
Sbjct: 345 ALVNFLGPLLFTFLVQLENYPPNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKS 404
Query: 363 TCDLCGYNQKLYPCWETQVGQEMYKLMIFDFIIILAVTLFVDFPRKLLVTYCSSCKLIQC 422
+C+ GYN Y CWE VG+E+YKL IF+F++ +A V PR+LLV S +
Sbjct: 405 SCESYGYNVCDYQCWENSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSG----RF 460
Query: 423 WG---QQEFAIPDNVLGIVYGQTICWIGAFFSPLLPAIATLKFIIIFYVKEWSLLYTCRP 479
W ++EF +P NVL IV GQT+ W+G F+ PLLP + ++ + FY+K+++LL R
Sbjct: 461 WAWLEREEFLVPKNVLDIVAGQTVTWMGLFYCPLLPLLNSVFLFLTFYIKKYTLLKNSRA 520
Query: 480 SPRPFRASNSNFFFLLVLLIGLCLAIIPLTISISRIPSSKACGPFTNFNTTWEVIPKTVS 539
S RPFRAS+S FFF LVLL+GL LA +PL +S I SS CG FTN++ W+V+P+ V+
Sbjct: 521 SSRPFRASSSTFFFQLVLLLGLLLAAVPLGYVVSSIHSSWDCGLFTNYSAPWQVVPELVA 580
Query: 540 T-FPSSLQSFIHGVTSEAFAVPFFMIICLIMFYFIALAGAHKRVVIQLREQLSLESRDKC 598
P Q +H + S AF+ P +++ L++ ++ A+ R + +LR+QL + ++K
Sbjct: 581 LGLPPIGQRALHYLGSHAFSFPLLIMLSLVLTVCVSQTQANARAIHRLRKQLVWQVQEKW 640
Query: 599 YLIQKLT 605
+L++ L+
Sbjct: 641 HLVEDLS 647
>gi|21071070 transmembrane channel-like 1 [Homo sapiens]
Length = 760
Score = 229 bits (584), Expect = 6e-60
Identities = 168/645 (26%), Positives = 292/645 (45%), Gaps = 77/645 (11%)
Query: 7 WDQWKRYSSKSWKRFLEKAREMTTHLELWREDIRSIEGKFGTGIQSYFSFLRFLVLLNLV 66
W +K +K W +FL W I++IE +FG+ + SYF FLR++ +N+V
Sbjct: 142 WFAFKMMMAKKWAKFLRDFENFKAACVPWENKIKAIESQFGSSVASYFLFLRWMYGVNMV 201
Query: 67 IFLIIFMLVLLPVLLTKYKITNSSFVLIPFKDMDKQCTVYPVSSSGLIYFYSYIIDLLSG 126
+F++ F L++LP L + +P + ++ G++Y ++
Sbjct: 202 LFILTFSLIMLPEYLWGLPYGSLPRKTVP------RAEEASAANFGVLYDFN-------- 247
Query: 127 TGFLEETSLFYGHY----TIDGVKFQNFTYDLPLAYLLSTIASLALSLLWIVKRSVEGFK 182
G + + LFYG+Y TI + F+ LPL+Y L I + S L ++K +
Sbjct: 248 -GLAQYSVLFYGYYDNKRTIGWMNFR-----LPLSYFLVGIMCIGYSFLVVLKAMTKNIG 301
Query: 183 INLIRSEEHFQSYCNKIFAGWDFCITNRSMADLKHSSLRYELRADLEEERMRQKIAERTS 242
+ + F ++ K+F WD+ I N AD K +S+ + + EE+ A +
Sbjct: 302 DDGGGDDNTF-NFSWKVFTSWDYLIGNPETADNKFNSITMNFKEAITEEK-----AAQVE 355
Query: 243 EETIRIYSLRLFLNCIVLAVLGACFYAIYVATVFSQEHMKKEIDKMVFGENLFILYLPSI 302
E I LR N V LG Y I+ A SQE +++ D + + E + ++
Sbjct: 356 ENVHLIRFLRFLANFFVFLTLGGSGYLIFWAVKRSQEFAQQDPDTLGWWEKNEM----NM 411
Query: 303 VITLANFITPMIFAKIIRYEDYSPGFEIRLTILRCVFMRLATICVLVFTLGSKITSCDDD 362
V++L P +F EDY P ++ + R + L + V + L +I + ++
Sbjct: 412 VMSLLGMFCPTLFDLFAELEDYHPLIALKWLLGRIFALLLGNLYVFILALMDEINNKIEE 471
Query: 363 TCDLCGYNQKLY-------------------------------PCWETQVGQEMYKLMIF 391
L N L+ PCWET VGQE +L +
Sbjct: 472 E-KLVKANITLWEANMIKAYNASFSENSTGPPFFVHPADVPRGPCWETMVGQEFVRLTVS 530
Query: 392 DFIIILAVTLFVDFPRKLLVTYCSSCKLIQCWGQQ-------EFAIPDNVLGIVYGQTIC 444
D + L DF R V +C+ C CW + EF I NVL +++ Q +
Sbjct: 531 DVLTTYVTILIGDFLRACFVRFCNYC---WCWDLEYGYPSYTEFDISGNVLALIFNQGMI 587
Query: 445 WIGAFFSPLLPAIATLKFIIIFYVKEWSLLYTCRPSPRPFRASNSNFFFLLVLLIGLCLA 504
W+G+FF+P LP I L+ Y + W+++ P R F+AS SN F+L +LL+ L L+
Sbjct: 588 WMGSFFAPSLPGINILRLHTSMYFQCWAVMCCNVPEARVFKASRSNNFYLGMLLLILFLS 647
Query: 505 IIPLTISISRIPSSKACGPFTNFNTTWEVIPKTVS-TFPSSLQSFIHGVTSEAFAVPFFM 563
+P+ I +P S CGPF+ N +EVI +T+ FPS + + +++ + +
Sbjct: 648 TMPVLYMIVSLPPSFDCGPFSGKNRMFEVIGETLEHDFPSWMAKILRQLSNPGLVIAVIL 707
Query: 564 IICLIMFYFIALAGAHKRVVIQLREQLSLESRDKCYLIQKLTEAQ 608
++ L ++Y A A K + L++++ +++ + +K+ A+
Sbjct: 708 VMVLAIYYLNATAKGQKAANLDLKKKMKMQALENKMRNKKMAAAR 752
>gi|157426860 transmembrane channel-like 5 isoform a [Homo sapiens]
Length = 1006
Score = 228 bits (582), Expect = 1e-59
Identities = 166/604 (27%), Positives = 291/604 (48%), Gaps = 66/604 (10%)
Query: 15 SKSWKRFLEKAREMTTHLELWREDIRSIEGKFGTGIQSYFSFLRFLVLLNLVIFLIIFML 74
S++++R E+ + LW++ ++ I GKFGT + SYF+FLR+L+ N+ F++
Sbjct: 411 SRAYRRSKNSLSEILNSISLWQKTLKIIGGKFGTSVLSYFNFLRWLLKFNIFSFIL---- 466
Query: 75 VLLPVLLTKYKITNSSFVLIPFKDMDKQCTVYPVSSSGLIYFYSYIIDLLSGTGFLEETS 134
N SF++IP + K+ T+ +GL +F +G G+ +T
Sbjct: 467 -------------NFSFIIIPQFTVAKKNTL---QFTGLEFF--------TGVGYFRDTV 502
Query: 135 LFYGHYTIDGVKFQNF--TYDLPLAYLLSTIASLALSLLWIVKRSVEGFKINLIRSEEHF 192
++YG YT ++ N +Y++ LAY+ + A L ++ + F+ N I +
Sbjct: 503 MYYGFYTNSTIQHGNSGASYNMQLAYIFTIGACLTTCFFSLLFSMAKYFRNNFINPHIYS 562
Query: 193 QSYCNKIFAGWDFCITNRSMADLKHSSLRYELRADLEEERMRQKIAERTSEETIRIYSLR 252
IF WDF +T+ LK +L E+R +L E +RQ+ ++ T + + +S
Sbjct: 563 GGITKLIFC-WDFTVTHEKAVKLKQKNLSTEIRENLSE--LRQENSKLTFNQLLTRFSAY 619
Query: 253 LFLNCIVLAVLGACFYAIYVATVFSQEHMKKEIDKMVFGENLFILYLPSIVITLANFITP 312
+ + V AC A+Y ++ E +K + +L LP V++ N P
Sbjct: 620 MVAWVVSTGVAIACCAAVYYLAEYNLEFLKTHSNPGA------VLLLP-FVVSCINLAVP 672
Query: 313 MIFAKIIRYEDYS-PGFEIRLTILRCVFMRLATICVLVFTLGSKITSCDDDTCDLCGYNQ 371
I++ E Y P E+ + ++R +F++++ I +L + + + ++
Sbjct: 673 CIYSMFRLVERYEMPRHEVYVLLIRNIFLKISIIGILCYYWLNTVALSGEE--------- 723
Query: 372 KLYPCWETQVGQEMYKLMIFDFIIILAVTLFVDFPRKLLVTYCSSCKLIQCWGQQEFAIP 431
CWET +GQ++Y+L++ DF+ L + +F R+++ +LI G QEF I
Sbjct: 724 ----CWETLIGQDIYRLLLMDFVFSLVNSFLGEFLRRII-----GMQLITSLGLQEFDIA 774
Query: 432 DNVLGIVYGQTICWIGAFFSPLLPAIATLKFIIIFYVKEWSLLYTCRPSPRPFRASNSNF 491
NVL ++Y QT+ WIG FF PLLP I + I+FY K SL+ +P + +RAS
Sbjct: 775 RNVLELIYAQTLVWIGIFFCPLLPFIQMIMLFIMFYSKNISLMMNFQPPSKAWRASQMMT 834
Query: 492 FFLLVLLIGLCLAII-PLTISISRIPSSKACGPFTNFNTTWEVIPK---TVSTFPSSL-- 545
FF+ +L ++ L I+I R+ S CGPF I T+ST P L
Sbjct: 835 FFIFLLFFPSFTGVLCTLAITIWRLKPSADCGPFRGLPLFIHSIYSWIDTLSTRPGYLWV 894
Query: 546 -QSFIHGVTSEAFAVPFFMIICLIMFYFIALAGAHKRVVIQLREQLSLESRDKCYLIQKL 604
+ + + S F +I+ +I + + + K ++ L EQ+ E +DK +LI+KL
Sbjct: 895 VWIYRNLIGSVHFFFILTLIVLIITYLYWQITEGRKIMIRLLHEQIINEGKDKMFLIEKL 954
Query: 605 TEAQ 608
+ Q
Sbjct: 955 IKLQ 958
>gi|31377679 transmembrane channel-like 5 isoform c [Homo sapiens]
Length = 760
Score = 228 bits (582), Expect = 1e-59
Identities = 166/604 (27%), Positives = 291/604 (48%), Gaps = 66/604 (10%)
Query: 15 SKSWKRFLEKAREMTTHLELWREDIRSIEGKFGTGIQSYFSFLRFLVLLNLVIFLIIFML 74
S++++R E+ + LW++ ++ I GKFGT + SYF+FLR+L+ N+ F++
Sbjct: 165 SRAYRRSKNSLSEILNSISLWQKTLKIIGGKFGTSVLSYFNFLRWLLKFNIFSFIL---- 220
Query: 75 VLLPVLLTKYKITNSSFVLIPFKDMDKQCTVYPVSSSGLIYFYSYIIDLLSGTGFLEETS 134
N SF++IP + K+ T+ +GL +F +G G+ +T
Sbjct: 221 -------------NFSFIIIPQFTVAKKNTL---QFTGLEFF--------TGVGYFRDTV 256
Query: 135 LFYGHYTIDGVKFQNF--TYDLPLAYLLSTIASLALSLLWIVKRSVEGFKINLIRSEEHF 192
++YG YT ++ N +Y++ LAY+ + A L ++ + F+ N I +
Sbjct: 257 MYYGFYTNSTIQHGNSGASYNMQLAYIFTIGACLTTCFFSLLFSMAKYFRNNFINPHIYS 316
Query: 193 QSYCNKIFAGWDFCITNRSMADLKHSSLRYELRADLEEERMRQKIAERTSEETIRIYSLR 252
IF WDF +T+ LK +L E+R +L E +RQ+ ++ T + + +S
Sbjct: 317 GGITKLIFC-WDFTVTHEKAVKLKQKNLSTEIRENLSE--LRQENSKLTFNQLLTRFSAY 373
Query: 253 LFLNCIVLAVLGACFYAIYVATVFSQEHMKKEIDKMVFGENLFILYLPSIVITLANFITP 312
+ + V AC A+Y ++ E +K + +L LP V++ N P
Sbjct: 374 MVAWVVSTGVAIACCAAVYYLAEYNLEFLKTHSNPGA------VLLLP-FVVSCINLAVP 426
Query: 313 MIFAKIIRYEDYS-PGFEIRLTILRCVFMRLATICVLVFTLGSKITSCDDDTCDLCGYNQ 371
I++ E Y P E+ + ++R +F++++ I +L + + + ++
Sbjct: 427 CIYSMFRLVERYEMPRHEVYVLLIRNIFLKISIIGILCYYWLNTVALSGEE--------- 477
Query: 372 KLYPCWETQVGQEMYKLMIFDFIIILAVTLFVDFPRKLLVTYCSSCKLIQCWGQQEFAIP 431
CWET +GQ++Y+L++ DF+ L + +F R+++ +LI G QEF I
Sbjct: 478 ----CWETLIGQDIYRLLLMDFVFSLVNSFLGEFLRRII-----GMQLITSLGLQEFDIA 528
Query: 432 DNVLGIVYGQTICWIGAFFSPLLPAIATLKFIIIFYVKEWSLLYTCRPSPRPFRASNSNF 491
NVL ++Y QT+ WIG FF PLLP I + I+FY K SL+ +P + +RAS
Sbjct: 529 RNVLELIYAQTLVWIGIFFCPLLPFIQMIMLFIMFYSKNISLMMNFQPPSKAWRASQMMT 588
Query: 492 FFLLVLLIGLCLAII-PLTISISRIPSSKACGPFTNFNTTWEVIPK---TVSTFPSSL-- 545
FF+ +L ++ L I+I R+ S CGPF I T+ST P L
Sbjct: 589 FFIFLLFFPSFTGVLCTLAITIWRLKPSADCGPFRGLPLFIHSIYSWIDTLSTRPGYLWV 648
Query: 546 -QSFIHGVTSEAFAVPFFMIICLIMFYFIALAGAHKRVVIQLREQLSLESRDKCYLIQKL 604
+ + + S F +I+ +I + + + K ++ L EQ+ E +DK +LI+KL
Sbjct: 649 VWIYRNLIGSVHFFFILTLIVLIITYLYWQITEGRKIMIRLLHEQIINEGKDKMFLIEKL 708
Query: 605 TEAQ 608
+ Q
Sbjct: 709 IKLQ 712
>gi|94536852 transmembrane cochlear-expressed protein 2 [Homo
sapiens]
Length = 906
Score = 213 bits (541), Expect = 5e-55
Identities = 156/622 (25%), Positives = 288/622 (46%), Gaps = 74/622 (11%)
Query: 10 WKRYSSKSWKRFLEKAREMTTHLELWREDIRSIEGKFGTGIQSYFSFLRFLVLLNLVIFL 69
+K +K W +F T W I+ IE FG+ + SYF FLR++ +NLV+F
Sbjct: 209 YKMLMAKKWVKFKRDFDNFKTQCIPWEMKIKDIESHFGSSVASYFIFLRWMYGVNLVLFG 268
Query: 70 IIFMLVLLPVLLTKYKITNSSFVLIPFKDMDKQCTVYPVSSSGLIYFYSYIIDLLSGTGF 129
+IF LV++P +L + +P + +K +S + D G+
Sbjct: 269 LIFGLVIIPEVLMGMPYGSIPRKTVPRAEEEKAMD------------FSVLWDF---EGY 313
Query: 130 LEETSLFYGHY----TIDGVKFQNFTYDLPLAYLLSTIASLALSLLWIVKRSVEGFKINL 185
++ ++LFYG+Y TI ++ Y LP+AY + ++ SL+ +++ + +
Sbjct: 314 IKYSALFYGYYNNQRTIGWLR-----YRLPMAYFMVGVSVFGYSLIIVIRSMASNTQGST 368
Query: 186 IRSEEHFQSYCNKIFAGWDFCITNRSMADLKHSSLRYELRADLEEERMRQKIAERTSEET 245
E ++ K+F WD+ I N AD K++S+ + + +E+ E EE
Sbjct: 369 GEGESDNFTFSFKMFTSWDYLIGNSETADNKYASITTSFKESIVDEQ------ESNKEEN 422
Query: 246 IRIYS-LRLFLNCIVLAVLGACFYAIYVATVFSQEHMKKEIDKMVFGENLFILYLPSIVI 304
I + LR+ N +++ L Y IY SQ+ K + + IV+
Sbjct: 423 IHLTRFLRVLANFLIICCLCGSGYLIYFVVKRSQQFSKMQNVSWYERNEV------EIVM 476
Query: 305 TLANFITPMIFAKIIRYEDYSPGFEIRLTILRCVFMRLATICVLVFTLGSKI--TSCDDD 362
+L P +F I E+Y P ++ + R + L + + L + +++
Sbjct: 477 SLLGMFCPPLFETIAALENYHPRTGLKWQLGRIFALFLGNLYTFLLALMDDVHLKLANEE 536
Query: 363 TC------------DLCGYNQK-----LYP-------CWETQVGQEMYKLMIFDFIIILA 398
T + G+N+ L+P CWET VG E +L + D ++
Sbjct: 537 TIKNITHWTLFNYYNSSGWNESVPRPPLHPADVPRGSCWETAVGIEFMRLTVSDMLVTYI 596
Query: 399 VTLFVDFPRKLLVTYCSSCKLIQCWGQQ-------EFAIPDNVLGIVYGQTICWIGAFFS 451
L DF R V + + C CW + EF I NVLG+++ Q + W+G+F++
Sbjct: 597 TILLGDFLRACFVRFMNYC---WCWDLEAGFPSYAEFDISGNVLGLIFNQGMIWMGSFYA 653
Query: 452 PLLPAIATLKFIIIFYVKEWSLLYTCRPSPRPFRASNSNFFFLLVLLIGLCLAIIPLTIS 511
P L I L+ + Y + W+++ + P R F+AS SN F++ +LL+ L L+++P+ +
Sbjct: 654 PGLVGINVLRLLTSMYFQCWAVMSSNVPHERVFKASRSNNFYMGLLLLVLFLSLLPVAYT 713
Query: 512 ISRIPSSKACGPFTNFNTTWEVIPKTV-STFPSSLQSFIHGVTSEAFAVPFFMIICLIMF 570
I +P S CGPF+ N ++V+ +T+ + FP+ L + + +P +++ L ++
Sbjct: 714 IMSLPPSFDCGPFSGKNRMYDVLQETIENDFPTFLGKIFAFLANPGLIIPAILLMFLAIY 773
Query: 571 YFIALAGAHKRVVIQLREQLSL 592
Y +++ + R QLR+++ +
Sbjct: 774 YLNSVSKSLSRANAQLRKKIQV 795
>gi|157426862 transmembrane channel-like 5 isoform b [Homo sapiens]
Length = 948
Score = 202 bits (513), Expect = 1e-51
Identities = 140/505 (27%), Positives = 247/505 (48%), Gaps = 60/505 (11%)
Query: 15 SKSWKRFLEKAREMTTHLELWREDIRSIEGKFGTGIQSYFSFLRFLVLLNLVIFLIIFML 74
S++++R E+ + LW++ ++ I GKFGT + SYF+FLR+L+ N+ F++
Sbjct: 411 SRAYRRSKNSLSEILNSISLWQKTLKIIGGKFGTSVLSYFNFLRWLLKFNIFSFIL---- 466
Query: 75 VLLPVLLTKYKITNSSFVLIPFKDMDKQCTVYPVSSSGLIYFYSYIIDLLSGTGFLEETS 134
N SF++IP + K+ T+ +GL +F +G G+ +T
Sbjct: 467 -------------NFSFIIIPQFTVAKKNTL---QFTGLEFF--------TGVGYFRDTV 502
Query: 135 LFYGHYTIDGVKFQNF--TYDLPLAYLLSTIASLALSLLWIVKRSVEGFKINLIRSEEHF 192
++YG YT ++ N +Y++ LAY+ + A L ++ + F+ N I +
Sbjct: 503 MYYGFYTNSTIQHGNSGASYNMQLAYIFTIGACLTTCFFSLLFSMAKYFRNNFINPHIYS 562
Query: 193 QSYCNKIFAGWDFCITNRSMADLKHSSLRYELRADLEEERMRQKIAERTSEETIRIYSLR 252
IF WDF +T+ LK +L E+R +L E +RQ+ ++ T + + +S
Sbjct: 563 GGITKLIFC-WDFTVTHEKAVKLKQKNLSTEIRENLSE--LRQENSKLTFNQLLTRFSAY 619
Query: 253 LFLNCIVLAVLGACFYAIYVATVFSQEHMKKEIDKMVFGENLFILYLPSIVITLANFITP 312
+ + V AC A+Y ++ E +K + +L LP V++ N P
Sbjct: 620 MVAWVVSTGVAIACCAAVYYLAEYNLEFLKTHSNPGA------VLLLP-FVVSCINLAVP 672
Query: 313 MIFAKIIRYEDYS-PGFEIRLTILRCVFMRLATICVLVFTLGSKITSCDDDTCDLCGYNQ 371
I++ E Y P E+ + ++R +F++++ I +L + + + ++
Sbjct: 673 CIYSMFRLVERYEMPRHEVYVLLIRNIFLKISIIGILCYYWLNTVALSGEE--------- 723
Query: 372 KLYPCWETQVGQEMYKLMIFDFIIILAVTLFVDFPRKLLVTYCSSCKLIQCWGQQEFAIP 431
CWET +GQ++Y+L++ DF+ L + +F R+++ +LI G QEF I
Sbjct: 724 ----CWETLIGQDIYRLLLMDFVFSLVNSFLGEFLRRII-----GMQLITSLGLQEFDIA 774
Query: 432 DNVLGIVYGQTICWIGAFFSPLLPAIATLKFIIIFYVKEWSLLYTCRPSPRPFRASNSNF 491
NVL ++Y QT+ WIG FF PLLP I + I+FY K SL+ +P + +RAS
Sbjct: 775 RNVLELIYAQTLVWIGIFFCPLLPFIQMIMLFIMFYSKNISLMMNFQPPSKAWRASQMMT 834
Query: 492 FFLLVLLIGLCLAII-PLTISISRI 515
FF+ +L ++ L I+I RI
Sbjct: 835 FFIFLLFFPSFTGVLCTLAITIWRI 859
>gi|187608784 transmembrane channel-like 6 [Homo sapiens]
Length = 805
Score = 194 bits (492), Expect = 3e-49
Identities = 155/598 (25%), Positives = 275/598 (45%), Gaps = 84/598 (14%)
Query: 35 WREDIRSIEGKFGTGIQSYFSFLRFLVLLNLVIFLIIFMLVLLPVLLTKYKITNSSFVLI 94
WR ++ I G+FG+ + SYF FL+ L+ N ++ L++ ++ P + + + V
Sbjct: 230 WRYALKRIGGQFGSSVLSYFLFLKTLLAFNALLLLLLVAFIMGPQVAFPPALPGPAPV-- 287
Query: 95 PFKDMDKQCTVYPVSSSGLIYFYSYIIDLLSGTGFLEETSLFYGHYT-----------ID 143
CT ++LL+G G T ++YGHY+ +D
Sbjct: 288 --------CTG---------------LELLTGAGCFTHTVMYYGHYSNATLNQPCGSPLD 324
Query: 144 GV----KFQNFTYDLPLAYLLSTIASLALSLLWIVKRSVEGFKINLIRSEEHFQSYCNKI 199
G + Y++PLAYL + S ++ + +V F + R + +
Sbjct: 325 GSQCTPRVGGLPYNMPLAYLSTVGVSFFITCITLVYSMAHSFGESY-RVGSTSGIHAITV 383
Query: 200 FAGWDFCITNRSMADLKHSSLRYELRADLEEERMR---QKIAERTSEETIRIYSLRLFLN 256
F WD+ +T + + L+ ++R L+ L E ++R + + R + + L
Sbjct: 384 FCSWDYKVTQKRASRLQQDNIRTRLKELLAEWQLRHSPRSVCGRLRQAAV--------LG 435
Query: 257 CIVLAVLGACFYAIYVATVFSQEHMKKEIDKMVFGENLFILYLPSIVITLANFITPMIFA 316
+ L LG VFS+ ++ G+ +L LP +V+ L N P +
Sbjct: 436 LVWLLCLGTALGCAVAVHVFSEFMIQSP---EAAGQEAVLLVLP-LVVGLLNLGAPYLCR 491
Query: 317 KIIRYEDY-SPGFEIRLTILRCVFMRLATICVLVFT-LGSKITSCDDDTCDLCGYNQKLY 374
+ E + SP E+ + I R + ++LA + L + LG ++
Sbjct: 492 VLAALEPHDSPVLEVYVAICRNLILKLAILGTLCYHWLGRRVGVLQGQ------------ 539
Query: 375 PCWETQVGQEMYKLMIFDFIIILAVTLFVDFPRKLLVTYCSSCKLIQCWGQQEFAIPDNV 434
CWE VGQE+Y+ ++ DF+++L TLF + +++ S K ++ + EF I NV
Sbjct: 540 -CWEDFVGQELYRFLVMDFVLMLLDTLFGELVWRII-----SEKKLKRRRKPEFDIARNV 593
Query: 435 LGIVYGQTICWIGAFFSPLLPAIATLKFIIIFYVKEWSLLYTCRPSPRPFRASNSNFFFL 494
L ++YGQT+ W+G FSPLLPA+ +K +++FYVK+ SLL C+ RP+ AS+ + FL
Sbjct: 594 LELIYGQTLTWLGVLFSPLLPAVQIIKLLLVFYVKKTSLLANCQAPRRPWLASHMSTVFL 653
Query: 495 LVLLIGLCL-AIIPLTISISRIPSSKACGPFTNFNTTWEVIPKTVSTFPS-----SLQSF 548
+L L A + L ++ ++ S CGPF +T +E V + S +
Sbjct: 654 TLLCFPAFLGAAVFLCYAVWQVKPSSTCGPFRTLDTMYEAGRVWVRHLEAAGPRVSWLPW 713
Query: 549 IHGVTSEAFAVPFFM--IICLIMFYFIALAGAHKRVVIQLREQLSLESRDKCYLIQKL 604
+H E F + ++ +++ I + ++V+ L+EQ+S E DK +LI KL
Sbjct: 714 VHRYLMENTFFVFLVSALLLAVIYLNIQVVRGQRKVICLLKEQISNEGEDKIFLINKL 771
>gi|187608791 transmembrane channel-like 6 [Homo sapiens]
Length = 805
Score = 194 bits (492), Expect = 3e-49
Identities = 155/598 (25%), Positives = 275/598 (45%), Gaps = 84/598 (14%)
Query: 35 WREDIRSIEGKFGTGIQSYFSFLRFLVLLNLVIFLIIFMLVLLPVLLTKYKITNSSFVLI 94
WR ++ I G+FG+ + SYF FL+ L+ N ++ L++ ++ P + + + V
Sbjct: 230 WRYALKRIGGQFGSSVLSYFLFLKTLLAFNALLLLLLVAFIMGPQVAFPPALPGPAPV-- 287
Query: 95 PFKDMDKQCTVYPVSSSGLIYFYSYIIDLLSGTGFLEETSLFYGHYT-----------ID 143
CT ++LL+G G T ++YGHY+ +D
Sbjct: 288 --------CTG---------------LELLTGAGCFTHTVMYYGHYSNATLNQPCGSPLD 324
Query: 144 GV----KFQNFTYDLPLAYLLSTIASLALSLLWIVKRSVEGFKINLIRSEEHFQSYCNKI 199
G + Y++PLAYL + S ++ + +V F + R + +
Sbjct: 325 GSQCTPRVGGLPYNMPLAYLSTVGVSFFITCITLVYSMAHSFGESY-RVGSTSGIHAITV 383
Query: 200 FAGWDFCITNRSMADLKHSSLRYELRADLEEERMR---QKIAERTSEETIRIYSLRLFLN 256
F WD+ +T + + L+ ++R L+ L E ++R + + R + + L
Sbjct: 384 FCSWDYKVTQKRASRLQQDNIRTRLKELLAEWQLRHSPRSVCGRLRQAAV--------LG 435
Query: 257 CIVLAVLGACFYAIYVATVFSQEHMKKEIDKMVFGENLFILYLPSIVITLANFITPMIFA 316
+ L LG VFS+ ++ G+ +L LP +V+ L N P +
Sbjct: 436 LVWLLCLGTALGCAVAVHVFSEFMIQSP---EAAGQEAVLLVLP-LVVGLLNLGAPYLCR 491
Query: 317 KIIRYEDY-SPGFEIRLTILRCVFMRLATICVLVFT-LGSKITSCDDDTCDLCGYNQKLY 374
+ E + SP E+ + I R + ++LA + L + LG ++
Sbjct: 492 VLAALEPHDSPVLEVYVAICRNLILKLAILGTLCYHWLGRRVGVLQGQ------------ 539
Query: 375 PCWETQVGQEMYKLMIFDFIIILAVTLFVDFPRKLLVTYCSSCKLIQCWGQQEFAIPDNV 434
CWE VGQE+Y+ ++ DF+++L TLF + +++ S K ++ + EF I NV
Sbjct: 540 -CWEDFVGQELYRFLVMDFVLMLLDTLFGELVWRII-----SEKKLKRRRKPEFDIARNV 593
Query: 435 LGIVYGQTICWIGAFFSPLLPAIATLKFIIIFYVKEWSLLYTCRPSPRPFRASNSNFFFL 494
L ++YGQT+ W+G FSPLLPA+ +K +++FYVK+ SLL C+ RP+ AS+ + FL
Sbjct: 594 LELIYGQTLTWLGVLFSPLLPAVQIIKLLLVFYVKKTSLLANCQAPRRPWLASHMSTVFL 653
Query: 495 LVLLIGLCL-AIIPLTISISRIPSSKACGPFTNFNTTWEVIPKTVSTFPS-----SLQSF 548
+L L A + L ++ ++ S CGPF +T +E V + S +
Sbjct: 654 TLLCFPAFLGAAVFLCYAVWQVKPSSTCGPFRTLDTMYEAGRVWVRHLEAAGPRVSWLPW 713
Query: 549 IHGVTSEAFAVPFFM--IICLIMFYFIALAGAHKRVVIQLREQLSLESRDKCYLIQKL 604
+H E F + ++ +++ I + ++V+ L+EQ+S E DK +LI KL
Sbjct: 714 VHRYLMENTFFVFLVSALLLAVIYLNIQVVRGQRKVICLLKEQISNEGEDKIFLINKL 771
>gi|122937502 transmembrane channel-like 3 [Homo sapiens]
Length = 1100
Score = 146 bits (369), Expect = 5e-35
Identities = 85/231 (36%), Positives = 128/231 (55%), Gaps = 12/231 (5%)
Query: 376 CWETQVGQEMYKLMIFDFIIILAVTLFVDFPRKLLVTYCSSCKLIQCWGQQ-------EF 428
CWET VGQEM KL I D + +A L +DF R L V Y S CW + EF
Sbjct: 499 CWETYVGQEMLKLSIIDMLFTVASILLIDFFRGLFVRYLSD---YWCWDLESKFPEYGEF 555
Query: 429 AIPDNVLGIVYGQTICWIGAFFSPLLPAIATLKFIIIFYVKEWSLLYTCRPSPRPFRASN 488
I +NVL +VY Q + W+GAFFSP LPA LK I + Y++ W++L P + FRAS
Sbjct: 556 KIAENVLHLVYNQGMIWMGAFFSPCLPAFNVLKLIGLMYLRSWAVLTCNVPHQQVFRASR 615
Query: 489 SNFFFLLVLLIGLCLAIIPLTISISRIPSSKACGPFTNFNTTWEVIPKTVST-FPSSLQS 547
SN F+L +LL L L ++P +I R S CGPF+ ++++ +T+ FP S
Sbjct: 616 SNNFYLAMLLFMLFLCMLPTIFAIVRYKPSLNCGPFSGQEKIYDIVSETIEKDFPVWFGS 675
Query: 548 FIHGVTSEAFAVPFFMIICLIMFYFIALAGAHKRVVIQLREQL-SLESRDK 597
+ ++S +P +++ ++++Y ++A + K QL+ Q+ + S DK
Sbjct: 676 VVGHISSPVVILPAVLLLFMLIYYLQSIARSLKLSNHQLKMQIQNARSEDK 726
Score = 125 bits (314), Expect = 1e-28
Identities = 92/343 (26%), Positives = 155/343 (45%), Gaps = 30/343 (8%)
Query: 18 WKRFLEKAREMTTHLELWREDIRSIEGKFGTGIQSYFSFLRFLVLLNLVIFLIIFMLVLL 77
W++F A W I+ IE FG+G+ SYF FLR+L +N+V+ ++ +++
Sbjct: 106 WRKFARLACNFVVIFIPWEMRIKKIESHFGSGVASYFIFLRWLFGINIVLTIMTGAFIVI 165
Query: 78 PVLLTKYKITNSSFVLIPFKDMDKQCTVYPVSSSGLIYFYSYIIDLLSGTGFLEETSLFY 137
P L+ +++ IP + + + V S G G+L+ + LFY
Sbjct: 166 PELIAGQPFGSTARKTIPKEQVSSAQDLDTVWSLG---------------GYLQYSVLFY 210
Query: 138 GHYTIDGVKFQNFTYDLPLAYLLSTIASLALSLLWIVKRSVEGFKINLIRSEEHFQSYCN 197
G+Y + K Y LPLAY L +A A S + ++K+ + + +L + ++C
Sbjct: 211 GYYGRER-KIGRAGYRLPLAYFLVGMAVFAYSFIILLKKMAKNSRTSLASASNENYTFCW 269
Query: 198 KIFAGWDFCITNRSMADLKHSSLRYELRADLEEERMRQKIAERTSEETIRIYSLRLFLNC 257
++F WD+ I N A+ K +++ +R + EE+ ++K S+ LR+ N
Sbjct: 270 RVFCAWDYLIGNPEAAESKTAAIVNSIREAILEEQEKKK-----SKNLAVTICLRIIANI 324
Query: 258 IVLAVLGACFYAIYVATVFSQ--EHMKKEIDKMVFGENLFILYLPSIVITLANFITPMIF 315
+VL L Y IY SQ E KKE+ E S+V++L I P F
Sbjct: 325 LVLLSLAGSIYLIYFVVDRSQKLEQSKKELTLWEKNE-------VSVVVSLVTMIAPSAF 377
Query: 316 AKIIRYEDYSPGFEIRLTILRCVFMRLATICVLVFTLGSKITS 358
I E Y P +R + R + + L + L+ L K+ S
Sbjct: 378 DLIAALEMYHPRTTLRFQLARVLVLYLGNLYSLIIALLDKVNS 420
>gi|18677729 relaxin/insulin-like family peptide receptor 2 [Homo
sapiens]
Length = 754
Score = 38.1 bits (87), Expect = 0.024
Identities = 44/185 (23%), Positives = 76/185 (41%), Gaps = 30/185 (16%)
Query: 302 IVITLANFITPMIFAKII-RYEDYSPGFEIRLTILRCVFMRLATICVLVFTLGSKITSCD 360
+ + L ++T F I+ + + PG IL C++M I V+ F
Sbjct: 508 VSVLLLTYLTLEKFLVIVFPFSNIRPGKRQTSVILICIWMAGFLIAVIPFWN-------K 560
Query: 361 DDTCDLCGYNQKLYPCWETQ---VGQEMYKLMIFDFIIILA--------VTLFVDFPRKL 409
D + G N +P + Q +G + Y L IF + +LA +T+F +
Sbjct: 561 DYFGNFYGKNGVCFPLYYDQTEDIGSKGYSLGIFLGVNLLAFLIIVFSYITMFCSIQKTA 620
Query: 410 LVTYCSSCKLIQCWGQQEFAIPDNVLGIVYGQTICWIGAFFSPLLPAI------ATLKFI 463
L T ++ C+G+ E A+ + IV+ ICWI F +L +I
Sbjct: 621 LQT----TEVRNCFGR-EVAVANRFFFIVFSDAICWIPVFVVKILSLFRVEIPDTMTSWI 675
Query: 464 IIFYV 468
+IF++
Sbjct: 676 VIFFL 680
>gi|83700231 cytotoxic T-lymphocyte-associated protein 4 isoform b
precursor [Homo sapiens]
Length = 174
Score = 33.5 bits (75), Expect = 0.59
Identities = 15/65 (23%), Positives = 31/65 (47%), Gaps = 4/65 (6%)
Query: 300 PSIVITLANFITPMIFAKIIRYEDYSPGFEIRLTILRCVFMRLATICVLVFTLGSKITSC 359
P++V+ + I + Y E+R+T+LR ++ +C + +G+++T
Sbjct: 43 PAVVLASSRGIASFV----CEYASPGKATEVRVTVLRQADSQVTEVCAATYMMGNELTFL 98
Query: 360 DDDTC 364
DD C
Sbjct: 99 DDSIC 103
>gi|21361212 cytotoxic T-lymphocyte-associated protein 4 isoform a
precursor [Homo sapiens]
Length = 223
Score = 33.5 bits (75), Expect = 0.59
Identities = 15/65 (23%), Positives = 31/65 (47%), Gaps = 4/65 (6%)
Query: 300 PSIVITLANFITPMIFAKIIRYEDYSPGFEIRLTILRCVFMRLATICVLVFTLGSKITSC 359
P++V+ + I + Y E+R+T+LR ++ +C + +G+++T
Sbjct: 43 PAVVLASSRGIASFV----CEYASPGKATEVRVTVLRQADSQVTEVCAATYMMGNELTFL 98
Query: 360 DDDTC 364
DD C
Sbjct: 99 DDSIC 103
>gi|106067657 luteinizing hormone/choriogonadotropin receptor
precursor [Homo sapiens]
Length = 699
Score = 32.0 bits (71), Expect = 1.7
Identities = 22/80 (27%), Positives = 40/80 (50%), Gaps = 5/80 (6%)
Query: 54 FSFLRFLVLLNLVIFLIIFMLVLLPVLLTKYKITNSSFVLIPFKDMDKQCTVY-----PV 108
+ FLR L+ L ++ ++ M VL +L ++YK+T F++ D +Y V
Sbjct: 359 YDFLRVLIWLINILAIMGNMTVLFVLLTSRYKLTVPRFLMCNLSFADFCMGLYLLLIASV 418
Query: 109 SSSGLIYFYSYIIDLLSGTG 128
S +Y++ ID +G+G
Sbjct: 419 DSQTKGQYYNHAIDWQTGSG 438
>gi|24431958 solute carrier family 16, member 7 [Homo sapiens]
Length = 478
Score = 30.4 bits (67), Expect = 5.0
Identities = 20/67 (29%), Positives = 31/67 (46%), Gaps = 4/67 (5%)
Query: 279 EHMKKEIDKMVFGENLFILYLPSIVITLANFITPMIF----AKIIRYEDYSPGFEIRLTI 334
E + K +D +F F++YL VI F P+IF AK ++YS F + +
Sbjct: 231 EKVNKYLDFSLFKHRGFLIYLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAFLLSVMA 290
Query: 335 LRCVFMR 341
+F R
Sbjct: 291 FVDMFAR 297
>gi|21536376 ATP-binding cassette, sub-family A member 1 [Homo
sapiens]
Length = 2261
Score = 30.0 bits (66), Expect = 6.5
Identities = 30/127 (23%), Positives = 49/127 (38%), Gaps = 18/127 (14%)
Query: 442 TICWIGAFFSPLLPAIATLKFIIIFYVKEWSLLYTCRPSPRPFRASNSNFFFLLVLLIGL 501
+I W F S L+P + + +++ +K +LL P+ + F FL V +
Sbjct: 679 SILWFSWFISSLIPLLVSAGLLVVI-LKLGNLL--------PYSDPSVVFVFLSVFAVVT 729
Query: 502 CLAIIPLTISISRIPSSKACGPFTNFN--------TTW-EVIPKTVSTFPSSLQSFIHGV 552
L ++ SR + ACG F W + + T+ F S L G
Sbjct: 730 ILQCFLISTLFSRANLAAACGGIIYFTLYLPYVLCVAWQDYVGFTLKIFASLLSPVAFGF 789
Query: 553 TSEAFAV 559
E FA+
Sbjct: 790 GCEYFAL 796
>gi|4503175 chemokine (C-X-C motif) receptor 4 isoform b [Homo
sapiens]
Length = 352
Score = 29.6 bits (65), Expect = 8.5
Identities = 19/76 (25%), Positives = 40/76 (52%), Gaps = 8/76 (10%)
Query: 248 IYSLRLFLNCIVLAVLGACFYAIYVATVFSQEHMKKEIDKMVFGENLFILYLPSIVITLA 307
IY++ L+ + ++LA + Y V SQ K +K+V+ +++P++++T+
Sbjct: 115 IYTVNLYSSVLILAFISLDRYLAIVHATNSQRPRKLLAEKVVY----VGVWIPALLLTIP 170
Query: 308 NFITPMIFAKIIRYED 323
+F IFA + +D
Sbjct: 171 DF----IFANVSEADD 182
>gi|56790927 chemokine (C-X-C motif) receptor 4 isoform a [Homo
sapiens]
Length = 356
Score = 29.6 bits (65), Expect = 8.5
Identities = 19/76 (25%), Positives = 40/76 (52%), Gaps = 8/76 (10%)
Query: 248 IYSLRLFLNCIVLAVLGACFYAIYVATVFSQEHMKKEIDKMVFGENLFILYLPSIVITLA 307
IY++ L+ + ++LA + Y V SQ K +K+V+ +++P++++T+
Sbjct: 119 IYTVNLYSSVLILAFISLDRYLAIVHATNSQRPRKLLAEKVVY----VGVWIPALLLTIP 174
Query: 308 NFITPMIFAKIIRYED 323
+F IFA + +D
Sbjct: 175 DF----IFANVSEADD 186
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.330 0.143 0.444
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,187,774
Number of Sequences: 37866
Number of extensions: 887717
Number of successful extensions: 2770
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 2689
Number of HSP's gapped (non-prelim): 26
length of query: 613
length of database: 18,247,518
effective HSP length: 108
effective length of query: 505
effective length of database: 14,157,990
effective search space: 7149784950
effective search space used: 7149784950
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.