BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|238231397 coiled-coil domain containing 12 [Homo sapiens] (179 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|238231397 coiled-coil domain containing 12 [Homo sapiens] 352 7e-98 gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 52 3e-07 gi|221219020 NYD-SP11 protein [Homo sapiens] 51 5e-07 gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 50 8e-07 gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 49 2e-06 gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 47 1e-05 gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 47 1e-05 gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 44 7e-05 gi|102467235 inner centromere protein antigens 135/155kDa isofor... 44 7e-05 gi|102467242 inner centromere protein antigens 135/155kDa isofor... 44 7e-05 gi|12711674 UPF3 regulator of nonsense transcripts homolog B iso... 44 1e-04 gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 43 2e-04 gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 43 2e-04 gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 43 2e-04 gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 43 2e-04 gi|148746195 trichohyalin [Homo sapiens] 43 2e-04 gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 42 2e-04 gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 42 2e-04 gi|154354979 myosin X [Homo sapiens] 42 2e-04 gi|104526627 triadin [Homo sapiens] 42 2e-04 gi|4505101 microtubule-associated protein 7 [Homo sapiens] 42 3e-04 gi|22027541 programmed cell death 7 [Homo sapiens] 42 3e-04 gi|22758136 MAP7 domain containing 2 [Homo sapiens] 42 3e-04 gi|41152097 DNA segment on chromosome X and Y (unique) 155 expre... 41 6e-04 gi|147903302 MAP7 domain containing 3 [Homo sapiens] 41 6e-04 gi|117553580 adaptor-related protein complex 3, delta 1 subunit ... 40 8e-04 gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 40 0.001 gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 40 0.001 gi|88759339 aster-associated protein [Homo sapiens] 40 0.001 gi|149589021 doublecortin-like kinase 3 [Homo sapiens] 40 0.001 >gi|238231397 coiled-coil domain containing 12 [Homo sapiens] Length = 179 Score = 352 bits (904), Expect = 7e-98 Identities = 179/179 (100%), Positives = 179/179 (100%) Query: 1 MQDGRKGGAYAGKMEATTAGVGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREE 60 MQDGRKGGAYAGKMEATTAGVGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREE Sbjct: 1 MQDGRKGGAYAGKMEATTAGVGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREE 60 Query: 61 EEEGEKHRELRLRNYVPEDEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANL 120 EEEGEKHRELRLRNYVPEDEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANL Sbjct: 61 EEEGEKHRELRLRNYVPEDEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANL 120 Query: 121 APRKPDWDLKRDVAKKLEKLKKRTQRAIAELIRERLKGQEDSLASAVDAATEQKTCDSD 179 APRKPDWDLKRDVAKKLEKLKKRTQRAIAELIRERLKGQEDSLASAVDAATEQKTCDSD Sbjct: 121 APRKPDWDLKRDVAKKLEKLKKRTQRAIAELIRERLKGQEDSLASAVDAATEQKTCDSD 179 >gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sapiens] Length = 570 Score = 52.0 bits (123), Expect = 3e-07 Identities = 38/157 (24%), Positives = 83/157 (52%), Gaps = 7/157 (4%) Query: 23 RLEEEALRRKERLKALREKTGRKDKE---DGEPKTKHLREEEEEGEKHRELRLRNYVPED 79 R +EE +RR+E + +E+ R+ +E + E K + L E+ E EK RE + E Sbjct: 312 REQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEK 371 Query: 80 -EDLKKRRVPQAKPVAVEEKVKEQLEAAK-PEPVIEEVDLANLAPRKPDWDLKRDVAKKL 137 + +KR+ +AK EEK++EQ E + E +++E + + W+ + ++ ++ Sbjct: 372 IREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQE 431 Query: 138 EKLKKRTQRAIAELIRERLKGQEDSLASAVDAATEQK 174 EK++++ ++ + ++++ QE+ + + EQ+ Sbjct: 432 EKMRRQEEKIREQ--EKKIREQEEKIREQEEMMQEQE 466 Score = 44.7 bits (104), Expect = 4e-05 Identities = 35/150 (23%), Positives = 75/150 (50%), Gaps = 5/150 (3%) Query: 25 EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKK 84 EE+ R++E+++ EK ++++ E + K R+EE EK ++R + + +++ K Sbjct: 287 EEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKI 346 Query: 85 RRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKKRT 144 R + + + +EK++EQ E + E I E + K W + + ++ EK+ R Sbjct: 347 RELEE--KMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKM-WRQEEKIREQEEKI--RE 401 Query: 145 QRAIAELIRERLKGQEDSLASAVDAATEQK 174 Q + + E++ QE+ + + EQ+ Sbjct: 402 QEEMMQEQEEKMGEQEEKMWEQEEEMQEQE 431 Score = 40.4 bits (93), Expect = 8e-04 Identities = 34/169 (20%), Positives = 77/169 (45%), Gaps = 11/169 (6%) Query: 13 KMEATTAGVGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRL 72 K + A + R EE+ ++E+++ E ++++ GE + K +EEE E+ ++R Sbjct: 377 KRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRR 436 Query: 73 RNYVPEDEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRD 132 + +K R + K EEK++EQ E + + + ++ + + Sbjct: 437 QE--------EKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEE 488 Query: 133 VAKKLEKLKKRTQRAIAELIRERLKGQEDSLASAVDAATEQ--KTCDSD 179 ++ E+ + ++ I E E+++ QE+ + + EQ K C+ + Sbjct: 489 KMRRQEEKIREQEKKIREQ-EEKIREQEEMMQEQEEKMWEQEEKMCEQE 536 Score = 39.3 bits (90), Expect = 0.002 Identities = 36/146 (24%), Positives = 76/146 (52%), Gaps = 15/146 (10%) Query: 25 EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEE-GEKHRELRLRNYVPEDEDLK 83 +EE +RR+E +EK R+ +E + + ++E+EE+ GE+ ++ + ++++ K Sbjct: 430 QEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEK 489 Query: 84 KRRVPQAKPVAVEEKVKEQ-LEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKK 142 RR EEK++EQ + + E I E + + W+ + + ++ EK+++ Sbjct: 490 MRR--------QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 541 Query: 143 RTQ--RAIAELIRE---RLKGQEDSL 163 + + R E +RE RL+ QE+ + Sbjct: 542 QEEKMRRQEEKMREQEVRLRQQEEKM 567 Score = 32.0 bits (71), Expect = 0.29 Identities = 23/97 (23%), Positives = 48/97 (49%), Gaps = 8/97 (8%) Query: 6 KGGAYAGKMEATTAGVGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGE 65 K G GKM A + EE+ R++E+++ +K ++++ E + +EE+ E Sbjct: 468 KMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWE 527 Query: 66 KHRELRLRNYVPEDEDLKKRRVPQAKPVAVEEKVKEQ 102 + ++ + ++++ K RR EEK++EQ Sbjct: 528 QEEKMCEQEEKMQEQEEKMRR--------QEEKMREQ 556 >gi|221219020 NYD-SP11 protein [Homo sapiens] Length = 2873 Score = 51.2 bits (121), Expect = 5e-07 Identities = 39/140 (27%), Positives = 72/140 (51%), Gaps = 3/140 (2%) Query: 26 EEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKKR 85 E L E+ ++L + + +E+ E + + +REEEEE ++ E + E+E+ KK+ Sbjct: 2231 ESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKK 2290 Query: 86 RVPQAK-PVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKKRT 144 + + K V +E+V E+ E E E L++ + L+ +V ++ E LKK Sbjct: 2291 KKEKKKEEVQEKEEVFEEKEEIMSEE--ETESLSDEEEEEESCSLEEEVDREKEILKKEK 2348 Query: 145 QRAIAELIRERLKGQEDSLA 164 Q + E R+ L+G+E L+ Sbjct: 2349 QFKLQEQRRKSLRGRERVLS 2368 Score = 32.7 bits (73), Expect = 0.17 Identities = 44/175 (25%), Positives = 77/175 (44%), Gaps = 20/175 (11%) Query: 2 QDGRKGGAYAGKMEATTAGVGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEE 61 QD R+ GK + EE +R E+L EK +K K+ + K REEE Sbjct: 1625 QDDREMAQAEGKF-------AQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEE 1677 Query: 62 EEGEKHREL-RLRNYVPEDEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANL 120 + +K +L ++N + + K +PQ E+ + Q + E E D+ L Sbjct: 1678 KLAKKGGKLAEVKNILAQ----KVEELPQR-----EQNLDWQEKELAQELEELEWDMEEL 1728 Query: 121 APRKPDWDLKRDVAKKLEKLKKRTQRAIA-ELIRERLKGQEDSLASAVDAATEQK 174 + ++ +L ++ K +E+ KK + A RE+L +E LA + ++K Sbjct: 1729 SWKEE--ELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEK 1781 Score = 30.4 bits (67), Expect = 0.85 Identities = 43/182 (23%), Positives = 80/182 (43%), Gaps = 25/182 (13%) Query: 1 MQDGRKGGAYAGKMEATTAGVGRLEEEALRRKERLKALREK--------TGRK----DKE 48 +Q+ K + KM +GR E+ + +K +L RE+ T K K+ Sbjct: 1778 IQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKK 1837 Query: 49 DGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKKRRVPQAKPV-----AVEEKVKEQL 103 + + K+L +E+E+ + +E L Y E K+++ Q K + +V+E+L Sbjct: 1838 NLAQEKKNLAQEKEKLAQRKENLL--YNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKL 1895 Query: 104 EAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKKRTQRAIAELI----RERLKGQ 159 K + ++ LA K ++ +AKK EKL + + E ++RL+G+ Sbjct: 1896 TQEKETVIKKKEKLAE--TEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGE 1953 Query: 160 ED 161 D Sbjct: 1954 LD 1955 Score = 29.3 bits (64), Expect = 1.9 Identities = 39/163 (23%), Positives = 74/163 (45%), Gaps = 22/163 (13%) Query: 25 EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHREL---RLRNYVPEDED 81 +E+ + KE++ E+ GRK ++ E K K ++ E EL ++ Y ++ Sbjct: 1781 KEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLA 1840 Query: 82 LKKRRVPQAKPVAVEEKV-----KEQLEAAKPE--PVIEEVDLANLAPRKPDWDL---KR 131 +K+ + Q K + K KE+L +K + V ++ + N + + L K Sbjct: 1841 QEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKE 1900 Query: 132 DVAKKLEKLKKRTQRAIAELIRERLKGQEDSLASAVDAATEQK 174 V KK EKL + T++ + ++ EDSLA + ++K Sbjct: 1901 TVIKKKEKLAE-TEKKLVQV--------EDSLAKKQEKLAQEK 1934 Score = 28.9 bits (63), Expect = 2.5 Identities = 30/126 (23%), Positives = 60/126 (47%), Gaps = 14/126 (11%) Query: 25 EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELR------LRNYVPE 78 E+ ++ + + + K R +K+ + + K +EEE+ ++ R+L + YV Sbjct: 1564 EQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKI 1623 Query: 79 DEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLK-RDVAKKL 137 +D R + QA+ + KE+ A + E + +E + LA ++ K VA++ Sbjct: 1624 TQD--DREMAQAEGKFAQ---KEETLAQRGEKLSQEAE--KLAQKRKKLAKKWEKVAREE 1676 Query: 138 EKLKKR 143 EKL K+ Sbjct: 1677 EKLAKK 1682 >gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] Length = 2817 Score = 50.4 bits (119), Expect = 8e-07 Identities = 42/161 (26%), Positives = 76/161 (47%), Gaps = 13/161 (8%) Query: 23 RLEEEALRR-KERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRL---RNYVPE 78 R+EE+ E+LK L EK G +K +P + +RE E E E+ RE L + E Sbjct: 472 RMEEQRKAACAEKLKRLDEKLGILEK---QPSPEEIREREREKEREREKELEKEQEQERE 528 Query: 79 DEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLE 138 E K R Q K +E++ ++Q E K +E +L ++ + ++ K+ E Sbjct: 529 KEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECE 588 Query: 139 KLKKRTQRAIAELIRERLKGQEDSLASAVDAATEQKTCDSD 179 K+R E + E+++ +E +L V+ + +C+ + Sbjct: 589 LEKER------EKLEEKIEPREPNLEPMVEKQESENSCNKE 623 Score = 42.0 bits (97), Expect = 3e-04 Identities = 45/170 (26%), Positives = 80/170 (47%), Gaps = 35/170 (20%) Query: 1 MQDGRKGGAYAGKMEATTAGVGRLEE----EALRRKERLKAL-------------REKTG 43 M++ RK A A K++ +G LE+ E +R +ER K REK Sbjct: 473 MEEQRKA-ACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKER 531 Query: 44 RKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKKRR---------VPQAKPVA 94 KD+E + K K L E+E EK RE+ ++++L++++ Q K Sbjct: 532 EKDRERQQEKEKEL---EKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECE 588 Query: 95 VE---EKVKEQLEAAKP--EPVIEEVDLANLAPRKPDWDLKRDVAKKLEK 139 +E EK++E++E +P EP++E+ + N ++ + R + + EK Sbjct: 589 LEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEK 638 >gi|4503509 eukaryotic translation initiation factor 3, subunit 10 theta, 150/170kDa [Homo sapiens] Length = 1382 Score = 48.9 bits (115), Expect = 2e-06 Identities = 41/137 (29%), Positives = 71/137 (51%), Gaps = 23/137 (16%) Query: 31 RKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKKRRVPQA 90 RKERL++L + +++ E E + + +R+ EEE RLR E ++ +K R+ Q Sbjct: 578 RKERLESLNIQREKEELEQREAELQKVRKAEEE-------RLRQ---EAKEREKERILQE 627 Query: 91 KPVAVEEKVKEQLEAAKPEPV----IEEVDLANLAPRKPDWDLKRDVAKKLEKLKKRTQR 146 ++ V+E+LE K + +++D+ +L PD+ + + V ++LEK KK Q Sbjct: 628 HEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQV-EQLEKEKKELQ- 685 Query: 147 AIAELIRERLKGQEDSL 163 ERLK QE + Sbjct: 686 -------ERLKNQEKKI 695 Score = 31.6 bits (70), Expect = 0.38 Identities = 40/159 (25%), Positives = 67/159 (42%), Gaps = 30/159 (18%) Query: 21 VGRLEEEALRRKERLKALREKTGRKDK--------------EDGEPKTKHLREEEEEG-- 64 V +LE+E +ERLK +K ++ E+ K L E++EE Sbjct: 674 VEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERI 733 Query: 65 -----EKHRELRLRNYVP---EDEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVD 116 E+ + L +N + ED DL R+ A+ EEK+K+ E + E Sbjct: 734 TTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQF------EERLAEER 787 Query: 117 LANLAPRKPDWDLKRDVAKKLEKLKKRTQRAIAELIRER 155 L RK +R + EK ++ +RA ++++ER Sbjct: 788 HNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKER 826 Score = 30.0 bits (66), Expect = 1.1 Identities = 29/108 (26%), Positives = 47/108 (43%), Gaps = 5/108 (4%) Query: 23 RLEEEALRRKE--RLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDE 80 RLEE +RKE R+ REK +++E + + L+E EE R R E Sbjct: 790 RLEERKRQRKEERRITYYREK---EEEEQRRAEEQMLKEREERERAERAKREEELREYQE 846 Query: 81 DLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWD 128 +KK + K E +++E+ + E + + L+ R D D Sbjct: 847 RVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWGDRD 894 Score = 28.1 bits (61), Expect = 4.2 Identities = 25/93 (26%), Positives = 44/93 (47%), Gaps = 11/93 (11%) Query: 23 RLEEEALRRKERLKALREKTGR------KDKEDGEPKTKHLREEEEEGEK----HRELRL 72 RL EE R E K R++ R K++E+ + + +E EE E+ RE L Sbjct: 782 RLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEEL 841 Query: 73 RNYVPEDEDLKK-RRVPQAKPVAVEEKVKEQLE 104 R Y + L++ R + + + +EE+ + + E Sbjct: 842 REYQERVKKLEEVERKKRQRELEIEERERRREE 874 Score = 27.3 bits (59), Expect = 7.2 Identities = 21/78 (26%), Positives = 35/78 (44%), Gaps = 2/78 (2%) Query: 15 EATTAGVGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEE--GEKHRELRL 72 E A + EEE +ER+K L E +K + + E + + R EEE G+ + Sbjct: 828 ERERAERAKREEELREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLSRKD 887 Query: 73 RNYVPEDEDLKKRRVPQA 90 + D + R+ P+A Sbjct: 888 SRWGDRDSEGTWRKGPEA 905 >gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 750 Score = 46.6 bits (109), Expect = 1e-05 Identities = 38/170 (22%), Positives = 83/170 (48%), Gaps = 9/170 (5%) Query: 13 KMEATTAGVGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRL 72 KM + + EE+ R++E+++ EK R+ +E + + +RE+EE + ++ Sbjct: 497 KMHEQEEKIRKQEEKVWRQEEKIREQEEKI-REQEEKMWRQEEKIREQEEMWREEEKMHE 555 Query: 73 RNYVPEDEDLKKRRVPQAKPVAVEEKVKEQLEAA-KPEPVIEEVDLANLAPRKPDWDLKR 131 + + E+E KR+ + K EEK++EQ E + E I E + + W + Sbjct: 556 QEKIWEEE---KRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEE 612 Query: 132 DVAKKLEKLKKRTQRAIAELIRERLKGQEDSLASAVDAATEQ--KTCDSD 179 + ++ EK++++ ++ + E+++ QE+ + EQ K C+ + Sbjct: 613 KIREQEEKIQEQEEKIREQ--EEKIREQEEMTQEQEEKMGEQEEKMCEQE 660 Score = 39.7 bits (91), Expect = 0.001 Identities = 36/156 (23%), Positives = 72/156 (46%), Gaps = 21/156 (13%) Query: 25 EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKK 84 EE+ ++E+++ EK R+++ E + K R+EE EK ++R + + +++ K Sbjct: 320 EEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM 379 Query: 85 RRVPQ------------AKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRD 132 RR + + + +EK++EQ E + E I E + K W + Sbjct: 380 RRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKM-WRQEEK 438 Query: 133 VAKKLEKLKKRTQRA--------IAELIRERLKGQE 160 + ++ EK++++ ++ E IRE K QE Sbjct: 439 IREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQE 474 Score = 38.9 bits (89), Expect = 0.002 Identities = 37/155 (23%), Positives = 77/155 (49%), Gaps = 19/155 (12%) Query: 25 EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEE---------EGEKHRELRLRNY 75 +EE +RR+E + +E+ R+ +E + K +RE+EE E EK +E + + Sbjct: 375 KEEKMRRQEEMMWEKEEKIRELEEKMHEQEK-IREQEEKRQEEEKIREQEKRQEQEAKMW 433 Query: 76 VPED---EDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDL----ANLAPRKPDWD 128 E+ E +K R + K EEK+ EQ + + E E+ ++ + ++ W Sbjct: 434 RQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWR 493 Query: 129 LKRDVAKKLEKLKKRTQRAIAELIRERLKGQEDSL 163 K + ++ EK++K+ ++ + E+++ QE+ + Sbjct: 494 QKEKMHEQEEKIRKQEEKVWRQ--EEKIREQEEKI 526 Score = 38.1 bits (87), Expect = 0.004 Identities = 35/144 (24%), Positives = 72/144 (50%), Gaps = 4/144 (2%) Query: 23 RLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDL 82 R EE+ +E+++ EK ++++ E + K R+EE EK ++R + + +++ Sbjct: 304 RQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 363 Query: 83 KKRRVPQAKPVAVEEKVKEQLEA--AKPEPVIEEVDLANLAPRKPDWDLKRDVAKKL-EK 139 K RR + EEK++ Q E K E + E + + + + + KR +K+ E+ Sbjct: 364 KMRR-QEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ 422 Query: 140 LKKRTQRAIAELIRERLKGQEDSL 163 K++ Q A E+++ QE+ + Sbjct: 423 EKRQEQEAKMWRQEEKIREQEEKI 446 Score = 37.0 bits (84), Expect = 0.009 Identities = 32/153 (20%), Positives = 73/153 (47%), Gaps = 8/153 (5%) Query: 25 EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEE---EEGEKHRELRLRNYVPEDED 81 E+E + +E+ + +K R++++ E + K R+EE E+ EK +E + + E+ Sbjct: 555 EQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEE-- 612 Query: 82 LKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLK 141 K R + K EEK++EQ E + + + + + ++ + + ++ E+ Sbjct: 613 --KIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETM 670 Query: 142 KRTQRAIAELIRERLKGQEDSLASAVDAATEQK 174 R + I E ++++ QE+ + + EQ+ Sbjct: 671 WRQEEKIREQ-EKKIREQEEKIREQEEMMQEQE 702 Score = 36.6 bits (83), Expect = 0.012 Identities = 29/157 (18%), Positives = 74/157 (47%), Gaps = 11/157 (7%) Query: 25 EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKK 84 E++ R++E+++ EK R++++ E + K +EE+ ++ ++R + ++++ K Sbjct: 569 EDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKI 628 Query: 85 RRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKKRT 144 R EEK++EQ E + + + ++ + + + E+ + Sbjct: 629 REQ--------EEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQ 680 Query: 145 QRAIAELIRERLKGQEDSLASAVDAATEQ--KTCDSD 179 ++ I E E+++ QE+ + + EQ K C+ + Sbjct: 681 EKKIREQ-EEKIREQEEMMQEQEEKMWEQEEKMCEQE 716 Score = 35.4 bits (80), Expect = 0.026 Identities = 31/155 (20%), Positives = 78/155 (50%), Gaps = 4/155 (2%) Query: 21 VGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDE 80 V R EE+ ++E+ + EK +++++ E + K +EE+ E+ ++R + + +++ Sbjct: 586 VWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQ 645 Query: 81 DLKKRRVPQAKPVAVEEKVKEQLEAA-KPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEK 139 + +K + K EEK++EQ E + E I E + + + + + ++ EK Sbjct: 646 E-EKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEK 704 Query: 140 LKKRTQRAIAELIRERLKGQEDSLASAVDAATEQK 174 + ++ ++ + E+++ QE+ + + EQ+ Sbjct: 705 MWEQEEKMCEQ--EEKMQEQEEKMRRQEEKMWEQE 737 Score = 33.9 bits (76), Expect = 0.077 Identities = 34/160 (21%), Positives = 70/160 (43%), Gaps = 12/160 (7%) Query: 25 EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKK 84 EEE + +E + EK +++ + + H +EE+ ++ + R + E E+ K Sbjct: 468 EEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEE--K 525 Query: 85 RRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPD-----WDLKRDVAKKLEK 139 R + K EEK++EQ E + E + E + ++ + W + + ++ EK Sbjct: 526 IREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEK 585 Query: 140 L-----KKRTQRAIAELIRERLKGQEDSLASAVDAATEQK 174 + K R Q + E++ QE+ + + EQ+ Sbjct: 586 VWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQE 625 Score = 32.0 bits (71), Expect = 0.29 Identities = 30/153 (19%), Positives = 74/153 (48%), Gaps = 4/153 (2%) Query: 23 RLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDL 82 R EE+ ++E++ EK ++++ E + K ++EE+ E+ +++ + +++ Sbjct: 574 RQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQE- 632 Query: 83 KKRRVPQAKPVAVEEKVKEQLE-AAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLK 141 +K R + EEK+ EQ E + E ++E + + + ++ + ++ EK+ Sbjct: 633 EKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKI- 691 Query: 142 KRTQRAIAELIRERLKGQEDSLASAVDAATEQK 174 R Q + + E++ QE+ + + EQ+ Sbjct: 692 -REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQE 723 Score = 28.5 bits (62), Expect = 3.2 Identities = 21/121 (17%), Positives = 58/121 (47%), Gaps = 1/121 (0%) Query: 23 RLEEEALRRKERL-KALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDED 81 R +EE +R +E + + EK G ++++ E + K +EE + ++R + +++ Sbjct: 629 REQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQE 688 Query: 82 LKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLK 141 K R + E+ +++ + + E ++E + + W+ + + ++ EK++ Sbjct: 689 EKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 748 Query: 142 K 142 + Sbjct: 749 E 749 >gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] Length = 245 Score = 46.6 bits (109), Expect = 1e-05 Identities = 40/141 (28%), Positives = 63/141 (44%), Gaps = 13/141 (9%) Query: 26 EEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKKR 85 +E +++R K +++ GR KE E + K R+ EE E+ R+ R E ++ KKR Sbjct: 107 KEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKR 166 Query: 86 RVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLK-----RDVAKKLEKL 140 Q E K KE+ E K E N RK + + K + KK E+ Sbjct: 167 ERKQVGEKEEERKEKERKERKKRE--------RNRKERKKERERKERRERKKERKKKEER 218 Query: 141 KKRTQRAIAELIRERLKGQED 161 KK Q+ RE+ +G+ + Sbjct: 219 KKERQKDRQTNWREKERGKRE 239 Score = 44.3 bits (103), Expect = 6e-05 Identities = 39/145 (26%), Positives = 70/145 (48%), Gaps = 14/145 (9%) Query: 15 EATTAGVGRLEEEALRRKERL---KALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELR 71 E T G+ E E+ R+KER K RE+ + +E G+ + K R++EE K R Sbjct: 44 EIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRRE 103 Query: 72 LRNYVPEDEDLKKRRVPQAK-PVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLK 130 N E+++ +K++ + + + E K +E+ E K E E RK + + Sbjct: 104 KENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKER-------ERKKE---E 153 Query: 131 RDVAKKLEKLKKRTQRAIAELIRER 155 R+ ++ ++ KKR ++ + E ER Sbjct: 154 REKERERKERKKRERKQVGEKEEER 178 Score = 37.7 bits (86), Expect = 0.005 Identities = 31/130 (23%), Positives = 55/130 (42%), Gaps = 5/130 (3%) Query: 13 KMEATTAGVGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRL 72 K T+ G+ E RK + RE+ + +++ E K + RE ++ GEK E + Sbjct: 121 KERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERK- 179 Query: 73 RNYVPEDEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRD 132 ++ +K+R K E + KE+ E K EE R+ +W K Sbjct: 180 ----EKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKER 235 Query: 133 VAKKLEKLKK 142 ++ ++ KK Sbjct: 236 GKRERKERKK 245 Score = 33.9 bits (76), Expect = 0.077 Identities = 32/137 (23%), Positives = 64/137 (46%), Gaps = 2/137 (1%) Query: 25 EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKK 84 E E RKE K RE +K++ + E K K RE+E + E+ ++ + E+ + KK Sbjct: 42 EREIETRKEGKKE-RESERKKERRERE-KRKREREKERKRERGKKEKKGERKKEERERKK 99 Query: 85 RRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKKRT 144 RR + E++ +++ E + +E + + K KK E+ K+R Sbjct: 100 RRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERE 159 Query: 145 QRAIAELIRERLKGQED 161 ++ + R+++ +E+ Sbjct: 160 RKERKKRERKQVGEKEE 176 >gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapiens] Length = 123 Score = 43.9 bits (102), Expect = 7e-05 Identities = 23/67 (34%), Positives = 41/67 (61%), Gaps = 1/67 (1%) Query: 25 EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKK 84 EEE +RK + K +E+ R+++E+ E + K EE+EEG + ++ + R E+E+ KK Sbjct: 56 EEEEKKRKRKRKKKKEEEEREEEEEEEEEEKE-EEEKEEGRRRKKKKKRRRKEEEEEKKK 114 Query: 85 RRVPQAK 91 +R + K Sbjct: 115 KRRRKTK 121 Score = 40.4 bits (93), Expect = 8e-04 Identities = 31/122 (25%), Positives = 57/122 (46%), Gaps = 8/122 (6%) Query: 25 EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKK 84 E E E + EK G++ + K K R+E+E+ +K +E R E+E +K Sbjct: 9 ETEETEETEETEEEEEKEGKR-----KEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRK 63 Query: 85 RRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKKRT 144 R+ + K E+ +E+ E K E EE + +K K + +K +K +++T Sbjct: 64 RKRKKKKEEEEREEEEEEEEEEKEE---EEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120 Query: 145 QR 146 ++ Sbjct: 121 KK 122 Score = 35.0 bits (79), Expect = 0.034 Identities = 27/116 (23%), Positives = 52/116 (44%) Query: 40 EKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKKRRVPQAKPVAVEEKV 99 +K +K KE E + EEEEE E R+ + + E E KK + + + EE+ Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 Query: 100 KEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKKRTQRAIAELIRER 155 K + + K + E + + + + K + ++ +K K+R + E ++R Sbjct: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKR 116 Score = 34.7 bits (78), Expect = 0.045 Identities = 26/119 (21%), Positives = 54/119 (45%), Gaps = 1/119 (0%) Query: 39 REKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKKRRVPQAKPVAVEEK 98 ++K +K+ E+ E +T+ EEEE+ K +E R +++ K + + K EEK Sbjct: 2 KKKKKKKETEETE-ETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60 Query: 99 VKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKKRTQRAIAELIRERLK 157 +++ K E E + K + + + +K +K ++R + + + R K Sbjct: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRK 119 >gi|102467235 inner centromere protein antigens 135/155kDa isoform 1 [Homo sapiens] Length = 918 Score = 43.9 bits (102), Expect = 7e-05 Identities = 37/153 (24%), Positives = 74/153 (48%), Gaps = 12/153 (7%) Query: 23 RLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDL 82 RL EE ++K K + E R+ +E+ + + L++EEEE +H+EL + E E L Sbjct: 617 RLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEE-RRHQELLQKKKEEEQERL 675 Query: 83 KK---------RRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDL--KR 131 +K +R + + E+ + + E + E +E LA R+ L +R Sbjct: 676 RKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAER 735 Query: 132 DVAKKLEKLKKRTQRAIAELIRERLKGQEDSLA 164 ++ ++ + L+ + ++ EL ++ K ++ LA Sbjct: 736 ELQEREKALRLQKEQLQRELEEKKKKEEQQRLA 768 Score = 41.2 bits (95), Expect = 5e-04 Identities = 39/148 (26%), Positives = 73/148 (49%), Gaps = 14/148 (9%) Query: 27 EALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKKRR 86 E LRRKE + LR + +DK + K REE + L+ R V + ++ KK++ Sbjct: 543 ENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREE----RLRKVLQARERVEQMKEEKKKQ 598 Query: 87 VPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRK-PDWDLKRDVAKKLEKLK---- 141 + Q K ++EK E AK E + EE A +K + + +R ++ +L+ Sbjct: 599 IEQ-KFAQIDEKT----EKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQ 653 Query: 142 KRTQRAIAELIRERLKGQEDSLASAVDA 169 + +R EL++++ + +++ L A +A Sbjct: 654 EEEERRHQELLQKKKEEEQERLRKAAEA 681 Score = 35.0 bits (79), Expect = 0.034 Identities = 42/170 (24%), Positives = 77/170 (45%), Gaps = 27/170 (15%) Query: 19 AGVGRLEEEALRRKERLKALR-------------EKTGRKDKEDGEPKTKHLRE-----E 60 A ++EE RRK+ +A R ++ +K KE+ + + + E E Sbjct: 627 AAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAE 686 Query: 61 EEEGEKHRELRLRNYVPEDEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANL 120 + E E+ + R E E ++ R Q + +A +E+ +EQ E + E ++E + A Sbjct: 687 QREQERREQERREQERREQERREQERREQERQLAEQERRREQ-ERLQAERELQEREKALR 745 Query: 121 APRKPDWDLKRDVAKKLEKLKKRTQRAIAELIRERLKGQEDSLASAVDAA 170 ++ L+R++ EK KK Q+ +AE R+ + QE A A+ Sbjct: 746 LQKE---QLQRELE---EKKKKEEQQRLAE--RQLQEEQEKKAKEAAGAS 787 Score = 31.2 bits (69), Expect = 0.50 Identities = 37/172 (21%), Positives = 74/172 (43%), Gaps = 36/172 (20%) Query: 23 RLEEEALRRKERL------------------KALREKTGRKDKEDGEPKTKHLREE---- 60 RLEE L+R+ERL K + +K + D++ + K + L EE Sbjct: 566 RLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKK 625 Query: 61 --------EEEGEKHRE---LRLRNYVPEDEDLKKRRVPQAKPVAVEEKVKEQLEAAKPE 109 E E + +E RLR E+E+ + + + Q K +E++++ EA + Sbjct: 626 KAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKR-- 683 Query: 110 PVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKKRTQRAIAELIRERLKGQED 161 + E+ + + + + + ++ E+ ++ Q A E RE+ + Q + Sbjct: 684 -LAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAE 734 Score = 30.0 bits (66), Expect = 1.1 Identities = 26/81 (32%), Positives = 38/81 (46%), Gaps = 1/81 (1%) Query: 25 EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKK 84 E+E R +ERL+A RE R +K K + RE EE+ +K + RL ++E KK Sbjct: 721 EQERRREQERLQAERELQER-EKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKK 779 Query: 85 RRVPQAKPVAVEEKVKEQLEA 105 + A+ V Q A Sbjct: 780 AKEAAGASKALNVTVDVQSPA 800 >gi|102467242 inner centromere protein antigens 135/155kDa isoform 2 [Homo sapiens] Length = 914 Score = 43.9 bits (102), Expect = 7e-05 Identities = 37/153 (24%), Positives = 74/153 (48%), Gaps = 12/153 (7%) Query: 23 RLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDL 82 RL EE ++K K + E R+ +E+ + + L++EEEE +H+EL + E E L Sbjct: 613 RLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEE-RRHQELLQKKKEEEQERL 671 Query: 83 KK---------RRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDL--KR 131 +K +R + + E+ + + E + E +E LA R+ L +R Sbjct: 672 RKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAER 731 Query: 132 DVAKKLEKLKKRTQRAIAELIRERLKGQEDSLA 164 ++ ++ + L+ + ++ EL ++ K ++ LA Sbjct: 732 ELQEREKALRLQKEQLQRELEEKKKKEEQQRLA 764 Score = 41.2 bits (95), Expect = 5e-04 Identities = 39/148 (26%), Positives = 73/148 (49%), Gaps = 14/148 (9%) Query: 27 EALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKKRR 86 E LRRKE + LR + +DK + K REE + L+ R V + ++ KK++ Sbjct: 539 ENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREE----RLRKVLQARERVEQMKEEKKKQ 594 Query: 87 VPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRK-PDWDLKRDVAKKLEKLK---- 141 + Q K ++EK E AK E + EE A +K + + +R ++ +L+ Sbjct: 595 IEQ-KFAQIDEKT----EKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQ 649 Query: 142 KRTQRAIAELIRERLKGQEDSLASAVDA 169 + +R EL++++ + +++ L A +A Sbjct: 650 EEEERRHQELLQKKKEEEQERLRKAAEA 677 Score = 35.0 bits (79), Expect = 0.034 Identities = 42/170 (24%), Positives = 77/170 (45%), Gaps = 27/170 (15%) Query: 19 AGVGRLEEEALRRKERLKALR-------------EKTGRKDKEDGEPKTKHLRE-----E 60 A ++EE RRK+ +A R ++ +K KE+ + + + E E Sbjct: 623 AAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAE 682 Query: 61 EEEGEKHRELRLRNYVPEDEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANL 120 + E E+ + R E E ++ R Q + +A +E+ +EQ E + E ++E + A Sbjct: 683 QREQERREQERREQERREQERREQERREQERQLAEQERRREQ-ERLQAERELQEREKALR 741 Query: 121 APRKPDWDLKRDVAKKLEKLKKRTQRAIAELIRERLKGQEDSLASAVDAA 170 ++ L+R++ EK KK Q+ +AE R+ + QE A A+ Sbjct: 742 LQKE---QLQRELE---EKKKKEEQQRLAE--RQLQEEQEKKAKEAAGAS 783 Score = 31.2 bits (69), Expect = 0.50 Identities = 37/172 (21%), Positives = 74/172 (43%), Gaps = 36/172 (20%) Query: 23 RLEEEALRRKERL------------------KALREKTGRKDKEDGEPKTKHLREE---- 60 RLEE L+R+ERL K + +K + D++ + K + L EE Sbjct: 562 RLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKK 621 Query: 61 --------EEEGEKHRE---LRLRNYVPEDEDLKKRRVPQAKPVAVEEKVKEQLEAAKPE 109 E E + +E RLR E+E+ + + + Q K +E++++ EA + Sbjct: 622 KAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKR-- 679 Query: 110 PVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKKRTQRAIAELIRERLKGQED 161 + E+ + + + + + ++ E+ ++ Q A E RE+ + Q + Sbjct: 680 -LAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAE 730 Score = 30.0 bits (66), Expect = 1.1 Identities = 26/81 (32%), Positives = 38/81 (46%), Gaps = 1/81 (1%) Query: 25 EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKK 84 E+E R +ERL+A RE R +K K + RE EE+ +K + RL ++E KK Sbjct: 717 EQERRREQERLQAERELQER-EKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKK 775 Query: 85 RRVPQAKPVAVEEKVKEQLEA 105 + A+ V Q A Sbjct: 776 AKEAAGASKALNVTVDVQSPA 796 >gi|12711674 UPF3 regulator of nonsense transcripts homolog B isoform 2 [Homo sapiens] Length = 470 Score = 43.5 bits (101), Expect = 1e-04 Identities = 39/153 (25%), Positives = 73/153 (47%), Gaps = 20/153 (13%) Query: 25 EEEALRRK--ERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDL 82 EEE +RK E+LK + ++ +DK EPK K L++ E+ EK + R + + E+L Sbjct: 238 EEEKRKRKDIEKLKKI-DRIPERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKLDKENL 296 Query: 83 KKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKK 142 R + + ++ +L+ K P++P+ + RD ++ + ++ Sbjct: 297 SDERA-SGQSCTLPKRSDSELKDEK--------------PKRPEDESGRDYREREREYER 341 Query: 143 RTQRAIAELIRERLKGQEDSLASAVDAATEQKT 175 +R + E RERLK QE+ + ++KT Sbjct: 342 DQERILRE--RERLKRQEEERRRQKERYEKEKT 372 Score = 32.0 bits (71), Expect = 0.29 Identities = 23/89 (25%), Positives = 46/89 (51%), Gaps = 11/89 (12%) Query: 23 RLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDL 82 R +E LR +ERLK R++ R+ +++ K K + +EEE +K ++ LR+ Sbjct: 341 RDQERILRERERLK--RQEEERRRQKERYEKEKTFKRKEEEMKKEKD-TLRD-------- 389 Query: 83 KKRRVPQAKPVAVEEKVKEQLEAAKPEPV 111 K ++ + + EK +++ E K + + Sbjct: 390 KGKKAESTESIGSSEKTEKKEEVVKRDRI 418 >gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sapiens] Length = 1293 Score = 42.7 bits (99), Expect = 2e-04 Identities = 35/138 (25%), Positives = 68/138 (49%), Gaps = 9/138 (6%) Query: 23 RLEEEALRR-KERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDED 81 R +EEALRR +E+ ALR + ++++ E + L E E E+ R+ ++E Sbjct: 782 RKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRK--------QEEL 833 Query: 82 LKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLK 141 L+K+ AK EE+ + +LE + E L + + +L+ K+L + + Sbjct: 834 LRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQR 893 Query: 142 KRTQRAIAELIRERLKGQ 159 ++ Q A+ L +++ + Q Sbjct: 894 QQQQEALRRLQQQQQQQQ 911 Score = 39.3 bits (90), Expect = 0.002 Identities = 37/155 (23%), Positives = 75/155 (48%), Gaps = 18/155 (11%) Query: 7 GGAYAGKMEATTAGVGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHL--REEEEEG 64 G A + A +LE+E RR+ ++A RE+ RK +E+ + + + R++EEE Sbjct: 714 GPALEQLQQLEKAKAAKLEQE--RREAEMRAKREEEERKRQEELRRQQEEILRRQQEEER 771 Query: 65 EKHRELRLRNYVPEDEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRK 124 ++ E+E+L +R+ +A E+++ + + + E +E L L R+ Sbjct: 772 KRR----------EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERR 821 Query: 125 PDWDLKRDVAKKLEKLKKRTQRAIAELIRERLKGQ 159 + + +R K E+L ++ + A+ RE + Q Sbjct: 822 REEEERR----KQEELLRKQEEEAAKWAREEEEAQ 852 >gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sapiens] Length = 1320 Score = 42.7 bits (99), Expect = 2e-04 Identities = 35/138 (25%), Positives = 68/138 (49%), Gaps = 9/138 (6%) Query: 23 RLEEEALRR-KERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDED 81 R +EEALRR +E+ ALR + ++++ E + L E E E+ R+ ++E Sbjct: 809 RKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRK--------QEEL 860 Query: 82 LKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLK 141 L+K+ AK EE+ + +LE + E L + + +L+ K+L + + Sbjct: 861 LRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQR 920 Query: 142 KRTQRAIAELIRERLKGQ 159 ++ Q A+ L +++ + Q Sbjct: 921 QQQQEALRRLQQQQQQQQ 938 Score = 39.3 bits (90), Expect = 0.002 Identities = 37/155 (23%), Positives = 75/155 (48%), Gaps = 18/155 (11%) Query: 7 GGAYAGKMEATTAGVGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHL--REEEEEG 64 G A + A +LE+E RR+ ++A RE+ RK +E+ + + + R++EEE Sbjct: 741 GPALEQLQQLEKAKAAKLEQE--RREAEMRAKREEEERKRQEELRRQQEEILRRQQEEER 798 Query: 65 EKHRELRLRNYVPEDEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRK 124 ++ E+E+L +R+ +A E+++ + + + E +E L L R+ Sbjct: 799 KRR----------EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERR 848 Query: 125 PDWDLKRDVAKKLEKLKKRTQRAIAELIRERLKGQ 159 + + +R K E+L ++ + A+ RE + Q Sbjct: 849 REEEERR----KQEELLRKQEEEAAKWAREEEEAQ 879 >gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sapiens] Length = 1299 Score = 42.7 bits (99), Expect = 2e-04 Identities = 35/138 (25%), Positives = 68/138 (49%), Gaps = 9/138 (6%) Query: 23 RLEEEALRR-KERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDED 81 R +EEALRR +E+ ALR + ++++ E + L E E E+ R+ ++E Sbjct: 788 RKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRK--------QEEL 839 Query: 82 LKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLK 141 L+K+ AK EE+ + +LE + E L + + +L+ K+L + + Sbjct: 840 LRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQR 899 Query: 142 KRTQRAIAELIRERLKGQ 159 ++ Q A+ L +++ + Q Sbjct: 900 QQQQEALRRLQQQQQQQQ 917 Score = 39.3 bits (90), Expect = 0.002 Identities = 37/155 (23%), Positives = 75/155 (48%), Gaps = 18/155 (11%) Query: 7 GGAYAGKMEATTAGVGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHL--REEEEEG 64 G A + A +LE+E RR+ ++A RE+ RK +E+ + + + R++EEE Sbjct: 720 GPALEQLQQLEKAKAAKLEQE--RREAEMRAKREEEERKRQEELRRQQEEILRRQQEEER 777 Query: 65 EKHRELRLRNYVPEDEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRK 124 ++ E+E+L +R+ +A E+++ + + + E +E L L R+ Sbjct: 778 KRR----------EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERR 827 Query: 125 PDWDLKRDVAKKLEKLKKRTQRAIAELIRERLKGQ 159 + + +R K E+L ++ + A+ RE + Q Sbjct: 828 REEEERR----KQEELLRKQEEEAAKWAREEEEAQ 858 >gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapiens] Length = 1299 Score = 42.7 bits (99), Expect = 2e-04 Identities = 35/138 (25%), Positives = 68/138 (49%), Gaps = 9/138 (6%) Query: 23 RLEEEALRR-KERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDED 81 R +EEALRR +E+ ALR + ++++ E + L E E E+ R+ ++E Sbjct: 788 RKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRK--------QEEL 839 Query: 82 LKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLK 141 L+K+ AK EE+ + +LE + E L + + +L+ K+L + + Sbjct: 840 LRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQR 899 Query: 142 KRTQRAIAELIRERLKGQ 159 ++ Q A+ L +++ + Q Sbjct: 900 QQQQEALRRLQQQQQQQQ 917 Score = 39.3 bits (90), Expect = 0.002 Identities = 37/155 (23%), Positives = 75/155 (48%), Gaps = 18/155 (11%) Query: 7 GGAYAGKMEATTAGVGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHL--REEEEEG 64 G A + A +LE+E RR+ ++A RE+ RK +E+ + + + R++EEE Sbjct: 720 GPALEQLQQLEKAKAAKLEQE--RREAEMRAKREEEERKRQEELRRQQEEILRRQQEEER 777 Query: 65 EKHRELRLRNYVPEDEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRK 124 ++ E+E+L +R+ +A E+++ + + + E +E L L R+ Sbjct: 778 KRR----------EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERR 827 Query: 125 PDWDLKRDVAKKLEKLKKRTQRAIAELIRERLKGQ 159 + + +R K E+L ++ + A+ RE + Q Sbjct: 828 REEEERR----KQEELLRKQEEEAAKWAREEEEAQ 858 >gi|148746195 trichohyalin [Homo sapiens] Length = 1943 Score = 42.7 bits (99), Expect = 2e-04 Identities = 34/122 (27%), Positives = 58/122 (47%), Gaps = 4/122 (3%) Query: 25 EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKK 84 EEE L R+ER K R++ R+ +E+ E + + + EE EK R L E+E+L++ Sbjct: 1119 EEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQ 1178 Query: 85 RRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKKRT 144 + + + EE+ K + E + EE+ R D D + D+ + E K+ Sbjct: 1179 ----EEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENA 1234 Query: 145 QR 146 R Sbjct: 1235 VR 1236 Score = 42.7 bits (99), Expect = 2e-04 Identities = 39/138 (28%), Positives = 68/138 (49%), Gaps = 21/138 (15%) Query: 25 EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKK 84 EE+ LRR+ER + RE+ R EP+ K L EEE + HR+ R R ++ E++ L++ Sbjct: 1490 EEQQLRRQERDRKFREQELRSQ----EPERKFL---EEEQQLHRQQRQRKFLQEEQQLRR 1542 Query: 85 RRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKKRT 144 + Q + + K +E+ + + EE L+ +RD +LE+ K R Sbjct: 1543 QERGQQRRQDRDRKFREEEQLRQER---EEQQLSR---------QERDRKFRLEEQKVRR 1590 Query: 145 QRAIAELI--RERLKGQE 160 Q + + ++L+ QE Sbjct: 1591 QEQERKFMEDEQQLRRQE 1608 Score = 42.4 bits (98), Expect = 2e-04 Identities = 35/152 (23%), Positives = 70/152 (46%), Gaps = 1/152 (0%) Query: 23 RLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDL 82 R EE+ R + R + L E+ G++ ++ + + + L E EE+ EK L R+ DE+L Sbjct: 114 RQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEEL 173 Query: 83 KKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKK 142 ++R + + +EQL++ K E D L R+ ++ +K ++ ++ Sbjct: 174 WRQR-QEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRE 232 Query: 143 RTQRAIAELIRERLKGQEDSLASAVDAATEQK 174 R R E + + +E L + E++ Sbjct: 233 RQDRVFQEEEEKEWRKRETVLRKEEEKLQEEE 264 Score = 42.4 bits (98), Expect = 2e-04 Identities = 35/136 (25%), Positives = 72/136 (52%), Gaps = 15/136 (11%) Query: 25 EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKK 84 +E+ LRR+E + LR++ RK +ED + L +E EE + HR+ R R ++ E+ L++ Sbjct: 1600 DEQQLRRQEGQQQLRQERDRKFRED-----EQLLQEREEQQLHRQERDRKFLEEEPQLRR 1654 Query: 85 RRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKKRT 144 + Q + K +E+ E +++E + L R+ + D K ++ + ++R Sbjct: 1655 QEREQQLRHDRDRKFREE------EQLLQEGEEQQL--RRQERDRKFREEEQQLRRQERE 1706 Query: 145 QRAIAELIRERLKGQE 160 ++ + E ++L+ QE Sbjct: 1707 RKFLQE--EQQLRRQE 1720 Score = 42.0 bits (97), Expect = 3e-04 Identities = 37/152 (24%), Positives = 69/152 (45%), Gaps = 3/152 (1%) Query: 25 EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKK 84 EEE LR+ ER + RE+ + ++ + + LR ++EE + ++ R E ++ Sbjct: 274 EEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEE 333 Query: 85 RRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKKRT 144 RR Q + EE+ ++QL + E E+ + + L+R+ + E+ +R Sbjct: 334 RREQQLRR-EQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRRE 392 Query: 145 Q--RAIAELIRERLKGQEDSLASAVDAATEQK 174 Q R +L RE+ +E L EQ+ Sbjct: 393 QQLRREQQLRREQQLRREQQLRREQQLRREQQ 424 Score = 41.6 bits (96), Expect = 4e-04 Identities = 34/139 (24%), Positives = 74/139 (53%), Gaps = 16/139 (11%) Query: 26 EEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKK- 84 E+ LRR+++L+ RE+ R+++E+ + KH +E E+ K + R+++ +E+ ++ Sbjct: 410 EQQLRREQQLR--REQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERH 467 Query: 85 ---RRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLK 141 RR Q K EE+ + L+ +EE + R+ + L+R+ ++ E+ Sbjct: 468 EQERRKQQLKRDQEEERRERWLK-------LEEEERREQQERR-EQQLRREQEERREQRL 519 Query: 142 KRTQRAIAELIRERLKGQE 160 KR + E +++RL+ ++ Sbjct: 520 KRQEE--EERLQQRLRSEQ 536 Score = 41.6 bits (96), Expect = 4e-04 Identities = 42/147 (28%), Positives = 73/147 (49%), Gaps = 21/147 (14%) Query: 27 EALRRKERLKALREKTGRKD---------KEDGEPKTKHLREEEEEGEKHRELRLRNYVP 77 E RRK++LK +E+ R+ +E E + + LR E+EE RE RL+ Sbjct: 468 EQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEE---RREQRLKRQ-E 523 Query: 78 EDEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIE----EVDLANLAPRKPDWDLKRDV 133 E+E L++R + + +E+ +EQL + E +E E L + D LKR+ Sbjct: 524 EEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREE 583 Query: 134 AKKLEKLKKRTQRAIAELIRERLKGQE 160 ++ ++LK+ + E + +RLK +E Sbjct: 584 ERRQQRLKREQE----ERLEQRLKREE 606 Score = 40.8 bits (94), Expect = 6e-04 Identities = 39/169 (23%), Positives = 78/169 (46%), Gaps = 19/169 (11%) Query: 25 EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKK 84 EEE L R+E K R++ R+ +E+ E + + + EE EK R+ R R Y E+E ++ Sbjct: 1149 EEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQ 1208 Query: 85 RRVPQAKPVAVEEKVKEQLEAAKPEPV--------------IEEVDLANLAPRKPDWDLK 130 +R + + +K Q E K V +++ + L R+ DL+ Sbjct: 1209 KRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQ 1268 Query: 131 RDVAKKLEKLKKRTQRAIAELIR-----ERLKGQEDSLASAVDAATEQK 174 + ++ E+ +++ +R + R E+L+ +E A D ++++ Sbjct: 1269 HLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEE 1317 Score = 39.7 bits (91), Expect = 0.001 Identities = 28/136 (20%), Positives = 74/136 (54%), Gaps = 7/136 (5%) Query: 27 EALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKKRR 86 E R+E+ + RE+ R+++E E + + LR E+EE + ++LR ++E+ ++++ Sbjct: 323 EQQERREQQEERREQQLRREQE--ERREQQLRREQEEERREQQLRRE----QEEERREQQ 376 Query: 87 VPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKKR-TQ 145 + + + + E++++ + + + + + E L + + L+R+ + E+ ++R Q Sbjct: 377 LRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQ 436 Query: 146 RAIAELIRERLKGQED 161 + E +RLK +++ Sbjct: 437 KHEQERREQRLKREQE 452 Score = 39.3 bits (90), Expect = 0.002 Identities = 33/145 (22%), Positives = 71/145 (48%), Gaps = 10/145 (6%) Query: 25 EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKK 84 +EE R ++RL++ E+ R+++E+ + EE+ ++ RE RL+ E D Sbjct: 522 QEEEERLQQRLRS--EQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLL 579 Query: 85 RRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDL-----ANLAPRKPDWDLKRDVAKKLEK 139 +R + + ++ + +E+LE +E ++ L +P+ + ++ + K E+ Sbjct: 580 KREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQ 639 Query: 140 LKKRTQ---RAIAELIRERLKGQED 161 ++R Q R E +RLK +E+ Sbjct: 640 EERRQQQLRREQQERREQRLKREEE 664 Score = 39.3 bits (90), Expect = 0.002 Identities = 36/150 (24%), Positives = 75/150 (50%), Gaps = 19/150 (12%) Query: 25 EEEALRRKERLKALREKTGRKDKED----GEPKTKHLREE-------EEEGEKHRELRLR 73 EE LRR+ER + LR RK +E+ E + + LR + EEE + R+ R R Sbjct: 1648 EEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERER 1707 Query: 74 NYVPEDEDLKKRRVPQAKPVAVEEKVK---EQLEAAKPEPVIEEVDLANLAPRKPDWDLK 130 ++ E++ L+++ + + EE+++ EQ + + E + ++ L P + + L+ Sbjct: 1708 KFLQEEQQLRRQEL--ERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLR 1765 Query: 131 RDVAKKLEKLKKRTQRAIAELIRERLKGQE 160 R ++ ++ + ++ E ++L+ QE Sbjct: 1766 R---QERDRKFREEEQLRQEREEQQLRSQE 1792 Score = 38.9 bits (89), Expect = 0.002 Identities = 33/139 (23%), Positives = 69/139 (49%), Gaps = 9/139 (6%) Query: 25 EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKK 84 +++ LRR+++L+ +E+ R+ +E+ + +E E+ E+ RE +LR E + + Sbjct: 296 QQQRLRREQQLRRKQEEERREQQEE----RREQQERREQQEERREQQLRREQEERREQQL 351 Query: 85 RRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKKRT 144 RR Q + ++ +EQ E + + + E L + + L+R+ + E+ +R Sbjct: 352 RR-EQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 410 Query: 145 QRAIAELIRERLKGQEDSL 163 Q +L RE+ +E L Sbjct: 411 Q----QLRREQQLRREQQL 425 Score = 38.9 bits (89), Expect = 0.002 Identities = 36/147 (24%), Positives = 72/147 (48%), Gaps = 11/147 (7%) Query: 25 EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDL-- 82 EEE L R+ER K R++ R+ ++D + + K + EE EK R E+E+L Sbjct: 939 EEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQ 998 Query: 83 -------KKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAK 135 ++R + + + + K++L+ + + + EE + L R+ + + ++ + Sbjct: 999 EEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQ 1058 Query: 136 KLEKL--KKRTQRAIAELIRERLKGQE 160 + E+L ++R R EL R+ K +E Sbjct: 1059 EEEQLLGEERETRRRQELERQYRKEEE 1085 Score = 38.1 bits (87), Expect = 0.004 Identities = 40/150 (26%), Positives = 68/150 (45%), Gaps = 11/150 (7%) Query: 26 EEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEE----EGEKHRELRLRNYVPEDED 81 E+ RR + LK E+ ++ K + E + + + EE E E+ RE RL+ PE+E Sbjct: 570 EQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEE- 628 Query: 82 LKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKR--DVAKKLEK 139 RR K EE+ ++QL + E + + R + LKR + ++ ++ Sbjct: 629 ---RRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERL-EQRLKREHEEERREQE 684 Query: 140 LKKRTQRAIAELIRERLKGQEDSLASAVDA 169 L + Q E I+ R+ + L S DA Sbjct: 685 LAEEEQEQARERIKSRIPKWQWQLESEADA 714 Score = 38.1 bits (87), Expect = 0.004 Identities = 21/65 (32%), Positives = 39/65 (60%), Gaps = 3/65 (4%) Query: 25 EEEALRRKERLKALREKTGRKDKEDGEPKTKHLRE---EEEEGEKHRELRLRNYVPEDED 81 EE+ LR +ER + LR+ RK +E+ + ++ R+ EEE + R+ R R ++ E++ Sbjct: 1395 EEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQ 1454 Query: 82 LKKRR 86 L++ R Sbjct: 1455 LRQER 1459 Score = 37.7 bits (86), Expect = 0.005 Identities = 31/150 (20%), Positives = 74/150 (49%), Gaps = 22/150 (14%) Query: 23 RLEEEALRRKERLKA----LREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPE 78 R E++ RR+++L+ RE+ R+++E+ E + + LR E+EE + ++LR + Sbjct: 327 RREQQEERREQQLRREQEERREQQLRREQEE-ERREQQLRREQEEERREQQLRREQQLRR 385 Query: 79 DEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLE 138 ++ L++ E++++ + + + + + E L + + L+R+ ++ Sbjct: 386 EQQLRR-----------EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERH 434 Query: 139 KLKKRTQRAIAELIRER------LKGQEDS 162 + K +R L RE+ LK +E++ Sbjct: 435 EQKHEQERREQRLKREQEERRDWLKREEET 464 Score = 37.7 bits (86), Expect = 0.005 Identities = 37/150 (24%), Positives = 71/150 (47%), Gaps = 16/150 (10%) Query: 25 EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKK 84 EEE L+R+ER + L+E +EDG + + R +E+ R+ + R + E+E ++ Sbjct: 836 EEEQLQRRERAQQLQE------EEDGLQEDQERRRSQEQ---RRDQKWR-WQLEEERKRR 885 Query: 85 RRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKKRT 144 R AKP E+ KEQ + E ++ + ++ + + + E+L++ Sbjct: 886 RHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREE-----EQLQQEE 940 Query: 145 QRAIAELIRERLKGQEDSLASAVDAATEQK 174 ++ + E RE+ + QE D +QK Sbjct: 941 EQLLRE-EREKRRRQERERQYRKDKKLQQK 969 Score = 37.4 bits (85), Expect = 0.007 Identities = 40/151 (26%), Positives = 71/151 (47%), Gaps = 27/151 (17%) Query: 25 EEEALRRKERLKALREKTGRKDKEDGEPKTKH---LREEEEEGEKHRELRLRNYVPE--- 78 EEE L+R+ER K R++ R+ +E+ + + + LREE E ++ R+ R R Y + Sbjct: 909 EEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREERE--KRRRQERERQYRKDKKL 966 Query: 79 ---------DEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDL 129 +E K+RR + K EE+++++ E E + R+ +W+ Sbjct: 967 QQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKR--------RRQEWE- 1017 Query: 130 KRDVAKKLEKLKKRTQRAIAELIRERLKGQE 160 R KK E ++ Q E + RL+ +E Sbjct: 1018 -RQYRKKDELQQEEEQLLREEREKRRLQERE 1047 Score = 37.0 bits (84), Expect = 0.009 Identities = 35/133 (26%), Positives = 65/133 (48%), Gaps = 10/133 (7%) Query: 25 EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKK 84 EEE L R+E K R++ R+ +E+ E + + + EE EK R L E+E++++ Sbjct: 1089 EEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQ 1148 Query: 85 RRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKKRT 144 Q E++ +++LE E EE+ ++ + L R+ +K + ++R Sbjct: 1149 EE-EQLLREEPEKRRRQELERQYREE--EEL-------QQEEEQLLREEQEKRRQERERQ 1198 Query: 145 QRAIAELIRERLK 157 R EL R++ K Sbjct: 1199 YREEEELQRQKRK 1211 Score = 37.0 bits (84), Expect = 0.009 Identities = 34/132 (25%), Positives = 67/132 (50%), Gaps = 22/132 (16%) Query: 23 RLEEEALRRKERLKA-------LREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNY 75 R EE+ +RR+ER + LR++ RK +E+ + L +E EE + HR+ R R + Sbjct: 1433 REEEQQVRRQERERKFLEEEQQLRQERHRKFREE-----EQLLQEREEQQLHRQERDRKF 1487 Query: 76 VPEDEDLKKRRVPQAKPVAVEEKVKEQ-LEAAKPE-PVIEEVDLANLAPRKPDWDLKRDV 133 + E++ L+++ + K +EQ L + +PE +EE + R+ + + Sbjct: 1488 LEEEQQLRRQE--------RDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQ 1539 Query: 134 AKKLEKLKKRTQ 145 ++ E+ ++R Q Sbjct: 1540 LRRQERGQQRRQ 1551 Score = 36.6 bits (83), Expect = 0.012 Identities = 34/136 (25%), Positives = 68/136 (50%), Gaps = 15/136 (11%) Query: 25 EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKK 84 +EE LRR+E L+ R+ GR++K+ + + + R +EE EK E R R V E+ K Sbjct: 206 DEEQLRRRELLELRRK--GREEKQQ-QRRERQDRVFQEEEEK--EWRKRETVLRKEEEKL 260 Query: 85 RRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKKRT 144 + EE+ + Q E + E + +++ L + + + ++ ++ ++L+++ Sbjct: 261 Q----------EEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQ 310 Query: 145 QRAIAELIRERLKGQE 160 + E ER + QE Sbjct: 311 EEERREQQEERREQQE 326 Score = 36.6 bits (83), Expect = 0.012 Identities = 34/145 (23%), Positives = 68/145 (46%), Gaps = 10/145 (6%) Query: 23 RLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHR---ELRLRNYVPED 79 +LEEE R+E+ + ++ R+ +E E + K EEE ++ R +LR + Sbjct: 490 KLEEE--ERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERRE 547 Query: 80 EDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVD-----LANLAPRKPDWDLKRDVA 134 + LK+ + + E+++K + E + + + E + L + + LKR+ Sbjct: 548 QLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEV 607 Query: 135 KKLEKLKKRTQRAIAELIRERLKGQ 159 ++LE+ ++R QR E E + Q Sbjct: 608 ERLEQEERREQRLKREEPEEERRQQ 632 Score = 36.2 bits (82), Expect = 0.015 Identities = 30/138 (21%), Positives = 67/138 (48%), Gaps = 3/138 (2%) Query: 25 EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEK--HRELRLRNYVPEDEDL 82 EEE ++R LR++ + +E+ + + + L+EEEE+ K +ELR E + Sbjct: 240 EEEEKEWRKRETVLRKEEEKLQEEEPQ-RQRELQEEEEQLRKLERQELRRERQEEEQQQQ 298 Query: 83 KKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKK 142 + RR Q + EE+ ++Q E + + E+ + + + + +R+ + E+ ++ Sbjct: 299 RLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEE 358 Query: 143 RTQRAIAELIRERLKGQE 160 R ++ + E + Q+ Sbjct: 359 RREQQLRREQEEERREQQ 376 Score = 35.8 bits (81), Expect = 0.020 Identities = 25/91 (27%), Positives = 49/91 (53%), Gaps = 9/91 (9%) Query: 23 RLEEEALRRKERLKALREKTGRKDKEDGEPK---TKHLREEEEEGEKHRELRLRNYV--- 76 R EE+ LRR+ER + ++ + +++ E K + LR+E E+ + R+ R R + Sbjct: 1694 REEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEE 1753 Query: 77 ---PEDEDLKKRRVPQAKPVAVEEKVKEQLE 104 PE E+ + RR + + EE+++++ E Sbjct: 1754 QLRPEREEQQLRRQERDRKFREEEQLRQERE 1784 Score = 33.5 bits (75), Expect = 0.100 Identities = 44/173 (25%), Positives = 75/173 (43%), Gaps = 53/173 (30%) Query: 23 RLEEEALRRKERLKALREKTGRKD---KEDGEPKTKHLREEEEEG--------------- 64 RLE+E RR++RLK RE+ R+D K + E + + L+ E+EE Sbjct: 557 RLEQE--RREQRLK--REQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQ 612 Query: 65 EKHRELRLRNYVPEDE---------------------DLKKRRVPQAKPVAVEEKVKEQL 103 E+ RE RL+ PE+E + ++RR + K EE+++++L Sbjct: 613 EERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRL 672 Query: 104 ------EAAKPEPVIEEVDLA--NLAPRKP--DWDLKRDVAKKLEKLKKRTQR 146 E + E EE + A + R P W L+ + + K+ R ++ Sbjct: 673 KREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRK 725 Score = 33.1 bits (74), Expect = 0.13 Identities = 32/150 (21%), Positives = 75/150 (50%), Gaps = 15/150 (10%) Query: 23 RLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDL 82 R +EE ++ + RE+ ++++E+ K EEE E+H + R + + D++ Sbjct: 427 REQEEERHEQKHEQERREQRLKREQEERRDWLK----REEETERHEQERRKQQLKRDQEE 482 Query: 83 KKR----RVPQAKPVAVEEKVKEQL----EAAKPEPVIEEVDLANLAPR-KPDWDLKRDV 133 ++R ++ + + +E+ ++QL E + + + + + L R + + L+R+ Sbjct: 483 ERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQ 542 Query: 134 AKKLEKLKKRTQ--RAIAELIRERLKGQED 161 ++ E+L KR + R E +RLK +++ Sbjct: 543 EERREQLLKREEEKRLEQERREQRLKREQE 572 Score = 31.6 bits (70), Expect = 0.38 Identities = 35/151 (23%), Positives = 72/151 (47%), Gaps = 14/151 (9%) Query: 25 EEEALRRKERLKAL---REKTGRKDKEDGEPKTKHLREEEE---EGEKHRELRLRNYVPE 78 EEE L R+ER K RE+ R+++E + + + L EE E E R+ R + + Sbjct: 1029 EEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQ 1088 Query: 79 DEDLKKRRVPQAKPVAVEE---KVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAK 135 +E+ R P+ + E + +E+L+ + + + EE + + + + +V + Sbjct: 1089 EEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQ 1148 Query: 136 KLEKL-----KKRTQRAIAELIRERLKGQED 161 + E+L +KR ++ + RE + Q++ Sbjct: 1149 EEEQLLREEPEKRRRQELERQYREEEELQQE 1179 Score = 30.8 bits (68), Expect = 0.65 Identities = 27/77 (35%), Positives = 39/77 (50%), Gaps = 16/77 (20%) Query: 25 EEEALRRKERLKALRE------KTGRKDKED------GEPKTKHLREEEEEGEKHRELRL 72 EE+ LRR+ER + RE + GRK E+ E + K L+EE++ + RE +L Sbjct: 1349 EEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQL 1408 Query: 73 RNYVPEDEDLKKRRVPQ 89 R +D D K R Q Sbjct: 1409 R----QDRDRKFREEEQ 1421 Score = 29.6 bits (65), Expect = 1.4 Identities = 11/45 (24%), Positives = 29/45 (64%) Query: 26 EEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHREL 70 +E RR+E+ E+ R+ + + + + +H+R +++E ++HR++ Sbjct: 1854 QEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQV 1898 Score = 29.3 bits (64), Expect = 1.9 Identities = 31/131 (23%), Positives = 62/131 (47%), Gaps = 22/131 (16%) Query: 25 EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKK 84 EE++ R ++RL A P + RE + E+ R+ R + ++PE+E+ ++ Sbjct: 774 EEKSERGRQRLSA-------------RPPLREQRERQLRAEE-RQQREQRFLPEEEEKEQ 819 Query: 85 RRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKKRT 144 RR + E+ KE L+ + E ++ + A + D L+ D ++ + ++R Sbjct: 820 RRRQR------REREKE-LQFLEEEEQLQRRERAQQLQEEED-GLQEDQERRRSQEQRRD 871 Query: 145 QRAIAELIRER 155 Q+ +L ER Sbjct: 872 QKWRWQLEEER 882 Score = 28.9 bits (63), Expect = 2.5 Identities = 30/143 (20%), Positives = 60/143 (41%), Gaps = 12/143 (8%) Query: 30 RRKERLKALREKT--GRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKK--- 84 R E+ + L + R+ ++D + +E + E E+ R + + PE+E L++ Sbjct: 1245 RENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQ 1304 Query: 85 -------RRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKL 137 R+ + K + EE+ +++ EE L +P +RD + Sbjct: 1305 KEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFRE 1364 Query: 138 EKLKKRTQRAIAELIRERLKGQE 160 E+L+ + Q +RL+ QE Sbjct: 1365 EELRHQEQGRKFLEEEQRLRRQE 1387 Score = 27.7 bits (60), Expect = 5.5 Identities = 26/84 (30%), Positives = 42/84 (50%), Gaps = 12/84 (14%) Query: 20 GVGRLEEEALRRKERLKALREKTGR--KDKEDGEPKTKHLREE----EEEGEKHRELRLR 73 G R EEE L+ +E+ + LR++ R + +E + K REE +EE +K R+ R R Sbjct: 1819 GKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERER 1878 Query: 74 NYVPE------DEDLKKRRVPQAK 91 E E+ + R+V + K Sbjct: 1879 KLREEHIRRQQKEEQRHRQVGEIK 1902 Score = 27.3 bits (59), Expect = 7.2 Identities = 20/86 (23%), Positives = 42/86 (48%), Gaps = 1/86 (1%) Query: 24 LEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLK 83 L+E+ + ++ L+ E+ R+++E + + + EEE + E +L E + Sbjct: 895 LQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQ 954 Query: 84 KRRVPQAKPVAVEEKVKEQLEAAKPE 109 +R K +++K +EQL +PE Sbjct: 955 ERERQYRKDKKLQQK-EEQLLGEEPE 979 >gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 899 Score = 42.4 bits (98), Expect = 2e-04 Identities = 36/160 (22%), Positives = 84/160 (52%), Gaps = 12/160 (7%) Query: 23 RLEEEALR-RKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDED 81 R EEE +R ++E+++ EK ++++ E + K +EE+ E+ ++ + E++ Sbjct: 599 REEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKM----WEQEEKM 654 Query: 82 LKKRRVPQAKPVAVE-EKVKEQLEAAKPEPVI---EEVDLANLAPRKPDWDLKRDVAKKL 137 +++R+P+ K E EK++EQ + + E I E+++ K WD ++ ++ Sbjct: 655 WEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEES 714 Query: 138 EKLKKRTQRAIAELIR---ERLKGQEDSLASAVDAATEQK 174 + +++ R E++R E+++ QE+ + + EQ+ Sbjct: 715 MREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQE 754 Score = 39.3 bits (90), Expect = 0.002 Identities = 39/147 (26%), Positives = 76/147 (51%), Gaps = 10/147 (6%) Query: 24 LEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEE----EEGEK--HRELRLRNYVP 77 L+EE R++E L+ +EK RK +E + + LRE+E E+ EK +E RLR Sbjct: 270 LQEEMWRQEEELRE-QEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEK 328 Query: 78 EDEDLKKRRVPQAKPVAVEEKVKEQLEAA-KPEPVIEEVDLANLAPRKPDWDLKRDVAKK 136 E + +K Q + EE+++EQ E + E + E + + W+ ++ + ++ Sbjct: 329 ELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQ 388 Query: 137 LEKLKKRTQRAIAELIRERLKGQEDSL 163 +K++ + +R + ERL+ +E+ + Sbjct: 389 EQKMRDQEERMWEQ--DERLREKEERM 413 Score = 38.1 bits (87), Expect = 0.004 Identities = 39/150 (26%), Positives = 75/150 (50%), Gaps = 13/150 (8%) Query: 21 VGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEE-GEKHRELRLRNYVPED 79 + + EE+ R++ERL+ +E R+ +E + K LRE+E+E E+ +ELR + + E Sbjct: 288 IRKQEEKMWRQEERLRE-QEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQ 346 Query: 80 EDLKKRRVPQAKPVAVEEKVKEQLEAA--------KPEPVIEEVDLANLAPRKPDWDLKR 131 E+ + + + K EEK++EQ E + E + E + + W+ Sbjct: 347 EEQMQEQ--EEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDE 404 Query: 132 DVAKKLEKLKKRTQR-AIAELIRERLKGQE 160 + +K E+++++ + E +RE K QE Sbjct: 405 RLREKEERMREQEKMWEQVEKMREEKKMQE 434 Score = 36.2 bits (82), Expect = 0.015 Identities = 33/141 (23%), Positives = 77/141 (54%), Gaps = 20/141 (14%) Query: 23 RLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDL 82 R +EE ++ +ER++ REK R+++E +RE+EE+ +K E + E+++ Sbjct: 440 RDQEEKMQEEERIRE-REKKMREEEET-------MREQEEKMQKQEE---NMWEQEEKEW 488 Query: 83 KKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKK 142 +++R+P+ K EK+ EQ + + E I E + + ++ W ++ + ++ EK+++ Sbjct: 489 QQQRLPEQK-----EKLWEQEKMQEQEEKIWEQE-EKIRDQEEMWGQEKKMWRQ-EKMRE 541 Query: 143 RTQRAIAELIRERLKGQEDSL 163 + + + E+++ QE + Sbjct: 542 QEDQMWEQ--EEKMRDQEQKM 560 Score = 34.7 bits (78), Expect = 0.045 Identities = 34/164 (20%), Positives = 76/164 (46%), Gaps = 16/164 (9%) Query: 25 EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKK 84 EEE +R +E+ E+T R+ +E + + +++ E+EE ++ ++ RL + + +K Sbjct: 448 EEERIREREKKMREEEETMREQEEKMQKQEENMWEQEE--KEWQQQRLPEQKEKLWEQEK 505 Query: 85 RRVPQAKPVAVEEKVKEQLE-------------AAKPEPVIEEVDLANLAPRKPDWDLKR 131 + + K EEK+++Q E + E + E + + WD + Sbjct: 506 MQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEE 565 Query: 132 DVAKKLEKLKKRTQRAIAEL-IRERLKGQEDSLASAVDAATEQK 174 + KK ++ +K+T ++ ER++ +E + + EQ+ Sbjct: 566 RMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQE 609 Score = 34.3 bits (77), Expect = 0.059 Identities = 28/151 (18%), Positives = 68/151 (45%), Gaps = 4/151 (2%) Query: 13 KMEATTAGVGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRL 72 KM+ + E+ + +E+ K ++ +++E + K +REEEE + E Sbjct: 678 KMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQ 737 Query: 73 RNYVPEDEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRD 132 E ++ + K EEK+ EQ + + + E + + ++ W+ + Sbjct: 738 EQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHE--KMQEQEKIWEQEEK 795 Query: 133 VAKKLEKLKKRTQRAIAELIRERLKGQEDSL 163 + + EK++ + ++ + E+++GQE+ + Sbjct: 796 MRDQEEKMRGQEEKMRGQ--EEKMRGQEEKM 824 Score = 31.6 bits (70), Expect = 0.38 Identities = 44/181 (24%), Positives = 84/181 (46%), Gaps = 29/181 (16%) Query: 20 GVGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEE-----------EEGEKHR 68 G R +EE + R+E+ +EK R+ +++ + K LRE+E E+ EK R Sbjct: 307 GKMREQEEKMWRQEKRLREQEKELREQEKELR-EQKELREQEEQMQEQEEKMWEQEEKMR 365 Query: 69 ELRLRNYVPED---EDLKKRRVPQAKPVAVEEKVKEQLEAAK--------PEPVIEEVDL 117 E + + E+ E K+ R + K EE++ EQ E + E + E+V+ Sbjct: 366 EQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEK 425 Query: 118 ANLAPRKPDWDLK-RDVAKKL---EKLKKRTQRAIAELIRERLKGQEDSLASAVDAATEQ 173 + + + K RD +K+ E++++R ++ E E ++ QE+ + + EQ Sbjct: 426 MREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREE--EETMREQEEKMQKQEENMWEQ 483 Query: 174 K 174 + Sbjct: 484 E 484 Score = 31.2 bits (69), Expect = 0.50 Identities = 24/90 (26%), Positives = 46/90 (51%), Gaps = 10/90 (11%) Query: 25 EEEALRRKERLKALREKTGRKDKEDGEPKT----KHLREEEEEGEKHRELRLRNYVPEDE 80 +EE +R +E+ +E+ K ++ E KT + +REEE E+ +++R + ++ Sbjct: 549 QEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQ 608 Query: 81 DLK------KRRVPQAKPVAVEEKVKEQLE 104 + K K + + K EEK++EQ E Sbjct: 609 EEKMQEQEEKMQEQEEKMWEQEEKMQEQEE 638 Score = 28.9 bits (63), Expect = 2.5 Identities = 33/145 (22%), Positives = 71/145 (48%), Gaps = 18/145 (12%) Query: 25 EEEALRRKERL----KALREKTGR-KDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPED 79 EE+ R++ERL K +RE+ + +D+E+ + E+EE + +E ++ V + Sbjct: 368 EEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQE-KMWEQVEKM 426 Query: 80 EDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEK 139 + KK + + K EEK++E+ + E + E + + R+ +K++K Sbjct: 427 REEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEE-----------ETMREQEEKMQK 475 Query: 140 LKKRT-QRAIAELIRERLKGQEDSL 163 ++ ++ E ++RL Q++ L Sbjct: 476 QEENMWEQEEKEWQQQRLPEQKEKL 500 >gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 828 Score = 42.4 bits (98), Expect = 2e-04 Identities = 39/147 (26%), Positives = 75/147 (51%), Gaps = 10/147 (6%) Query: 24 LEEEALRRKERLKALREKTGRKDKEDGEPKTKHLRE------EEEEGEKHRELRLRNYVP 77 L+EE R++E L+ +EK RK +E + + LRE E+EE + +E RLR Sbjct: 232 LQEEMWRQEEELRE-QEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEK 290 Query: 78 EDEDLKKRRVPQAKPVAVEEKVKEQLEAA-KPEPVIEEVDLANLAPRKPDWDLKRDVAKK 136 E + +K Q K EE+++EQ E + E + E + + W+ ++ + ++ Sbjct: 291 ELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQ 350 Query: 137 LEKLKKRTQRAIAELIRERLKGQEDSL 163 +K++ + +R + ERL+ +E+ + Sbjct: 351 EQKMRDQEERMWEQ--DERLREKEERM 375 Score = 38.1 bits (87), Expect = 0.004 Identities = 33/147 (22%), Positives = 71/147 (48%), Gaps = 10/147 (6%) Query: 25 EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKK 84 +EE +R +++ + +KT D+E+ + + +RE E++ + E+ E +K Sbjct: 532 QEEKMREEKKTQEQEKKTW--DQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEK 589 Query: 85 RRVPQAKPVAVEEKVKEQLEA--AKPEPVIEEVDLANLAPRKP-DWDLKRDVAKKLEKL- 140 R + K EEK++EQ E + E + E+ + + ++ W+ + + ++ EK+ Sbjct: 590 MREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMW 649 Query: 141 ----KKRTQRAIAELIRERLKGQEDSL 163 K R Q E+++GQE+ + Sbjct: 650 EQEEKMREQEEKMREQEEKMQGQEEKM 676 Score = 37.7 bits (86), Expect = 0.005 Identities = 34/155 (21%), Positives = 79/155 (50%), Gaps = 13/155 (8%) Query: 23 RLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEE----EEGEKHRELRLRNYVPE 78 RL E+ R +E+ K ++ +++E + K +REEE E+ EK ++ + E Sbjct: 367 RLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQE 426 Query: 79 DEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLE 138 +++ +++R+P+ K EK+ EQ + + E I E + + ++ W ++ + ++ E Sbjct: 427 EKEWQQQRLPEQK-----EKLWEQEKMQEQEEKIWEQE-EKIRDQEEMWGQEKKMWRQ-E 479 Query: 139 KLKKRTQRAIAELIRERLKGQEDSLASAVDAATEQ 173 K++++ + + E+++ QE + + EQ Sbjct: 480 KMREQEDQMWEQ--EEKMRDQEQKMWDQEERMWEQ 512 Score = 37.4 bits (85), Expect = 0.007 Identities = 34/153 (22%), Positives = 76/153 (49%), Gaps = 11/153 (7%) Query: 23 RLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDL 82 R +EE +R ++++ EK R++K+ E + K +EE+ E+ R + E+E++ Sbjct: 517 REKEERMREQKKMWQQEEKM-REEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEM 575 Query: 83 KKRRVPQAKPVAVEEKVKEQLEAA-KPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLK 141 + + + K EEK++EQ E + E ++E + + W+ + + ++ E+ K Sbjct: 576 MREQ--EEKMQEQEEKMREQEEKMWEQEEKMQEQE-------EKMWEQEEKMWEQEEEDK 626 Query: 142 KRTQRAIAELIRERLKGQEDSLASAVDAATEQK 174 + Q + E+++ QE+ + + EQ+ Sbjct: 627 MQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQE 659 Score = 36.6 bits (83), Expect = 0.012 Identities = 34/162 (20%), Positives = 77/162 (47%), Gaps = 12/162 (7%) Query: 23 RLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEE----EEGEKHRELRLRNYVPE 78 ++ EE +++ K ++ +++E + K +REEE E+ EK +E + E Sbjct: 535 KMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQE 594 Query: 79 D---EDLKKRRVPQAKPVAVEEKVKEQLEAAK---PEPVIEEVDLANLAPRKPDWDLKRD 132 + E +K + + K EEK+ EQ E K E ++ E + + W+ + Sbjct: 595 EKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEK 654 Query: 133 VAKKLEKLKKRTQRAIAELIRERLKGQEDSLASAVDAATEQK 174 + ++ EK++++ ++ + E+++ QE+ + + EQ+ Sbjct: 655 MREQEEKMREQEEKMQGQ--EEKMREQEEKMQGQEEKMREQE 694 Score = 33.9 bits (76), Expect = 0.077 Identities = 41/168 (24%), Positives = 81/168 (48%), Gaps = 23/168 (13%) Query: 20 GVGRLEEEALRRKE-RLKALREKTGRKDKEDGEPKTKHLREEE---------EEGEKHRE 69 G R +EE +RR+E RL+ ++ ++KE E K +EE+ E+ EK RE Sbjct: 269 GKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMRE 328 Query: 70 LRLRNYVPED---EDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPD 126 + + E+ E K+ R + K EE++ EQ E + + EE + ++ Sbjct: 329 QEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREK---EE----RMREQEKM 381 Query: 127 WDLKRDVAKKLEKLKKRTQRAIAELIRERLKGQEDSLASAVDAATEQK 174 W+ + + ++ E++++R ++ E E ++ QE+ + + EQ+ Sbjct: 382 WEQEEKMQEE-ERIREREKKMREE--EETMREQEEKMQKQEENMWEQE 426 Score = 33.5 bits (75), Expect = 0.100 Identities = 38/156 (24%), Positives = 73/156 (46%), Gaps = 24/156 (15%) Query: 25 EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKK 84 EEE +R +E+ E+T R+ +E + + +++ E+EE+ + + L PE K+ Sbjct: 390 EEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRL------PEQ---KE 440 Query: 85 RRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDW------DLKRDVAKKLE 138 + Q K EEK+ EQ E + + EE+ K W + + + ++ E Sbjct: 441 KLWEQEKMQEQEEKIWEQEEKIRDQ---EEM----WGQEKKMWRQEKMREQEDQMWEQEE 493 Query: 139 KLKKRTQRAIAELIRERLKGQEDSLASAVDAATEQK 174 K++ + Q+ + ER+ Q++ L + EQK Sbjct: 494 KMRDQEQKMWDQ--EERMWEQDERLREKEERMREQK 527 Score = 32.7 bits (73), Expect = 0.17 Identities = 34/163 (20%), Positives = 72/163 (44%), Gaps = 3/163 (1%) Query: 13 KMEATTAGVGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRL 72 KM + EE+ ++E++ EK +++ED + + + E+EE + +E ++ Sbjct: 589 KMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKM 648 Query: 73 RNYVPE-DEDLKKRRVPQAKPVAVEEKVKEQLEAAK-PEPVIEEVDLANLAPRKPDWDLK 130 + E +K R + K EEK++EQ E + E + E + + W + Sbjct: 649 WEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQE 708 Query: 131 RDVAKKLEKL-KKRTQRAIAELIRERLKGQEDSLASAVDAATE 172 + + EK+ + R E IR++ + ++ L + +E Sbjct: 709 EKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEERCSE 751 Score = 31.2 bits (69), Expect = 0.50 Identities = 26/155 (16%), Positives = 75/155 (48%), Gaps = 5/155 (3%) Query: 25 EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDE---- 80 +EE +R +E+ +E+ + E K + +RE+++ ++ ++R E E Sbjct: 491 QEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTW 550 Query: 81 DLKKRRVPQAKPVAVEEKVKEQLEAAK-PEPVIEEVDLANLAPRKPDWDLKRDVAKKLEK 139 D +++ + + E+K++E+ E + E ++E + + W+ + + ++ EK Sbjct: 551 DQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEK 610 Query: 140 LKKRTQRAIAELIRERLKGQEDSLASAVDAATEQK 174 + ++ ++ + ++++ QE+ + + EQ+ Sbjct: 611 MWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQE 645 Score = 27.3 bits (59), Expect = 7.2 Identities = 31/140 (22%), Positives = 70/140 (50%), Gaps = 11/140 (7%) Query: 25 EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEE-GEKHRELRLRNYVPEDEDLK 83 +EE L +E+ +E+ R +E + + LRE+EE E+ + + E+E ++ Sbjct: 336 QEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIR 395 Query: 84 KRRVPQAKPVAVEEKVKEQLE--AAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLK 141 +R + K EE ++EQ E + E + E+ + R P+ +++ + EK++ Sbjct: 396 ER---EKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPE---QKEKLWEQEKMQ 449 Query: 142 KRTQRAIAELIRERLKGQED 161 ++ ++ + E+++ QE+ Sbjct: 450 EQEEKIWEQ--EEKIRDQEE 467 >gi|154354979 myosin X [Homo sapiens] Length = 2058 Score = 42.4 bits (98), Expect = 2e-04 Identities = 36/143 (25%), Positives = 67/143 (46%), Gaps = 7/143 (4%) Query: 29 LRRKERLKALREKTGRKDKEDGEPKTKHLREEEE-EGEKHRELRLRNYVPEDEDLKKRRV 87 + R+ + L EK +++K+ E + K REEEE E E+ R E+E K++ + Sbjct: 803 IARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQEL 862 Query: 88 PQAKPVAVEEKVKEQLEAAKPEPVIEEV-----DLANLAPRKPDWDLKRDVAKKLEKLKK 142 + E ++ +LE K +EE+ ++ +L K +L A L+KL++ Sbjct: 863 EALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEA-SLQKLQE 921 Query: 143 RTQRAIAELIRERLKGQEDSLAS 165 R + + L E + ++ L S Sbjct: 922 RRDQELRRLEEEACRAAQEFLES 944 Score = 34.3 bits (77), Expect = 0.059 Identities = 32/131 (24%), Positives = 63/131 (48%), Gaps = 5/131 (3%) Query: 23 RLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLR-EEEEEGEKHRELRLRNYVPEDED 81 R +EE +++E K RE+ R+ + E + LR ++EEE K +EL ++ + Sbjct: 816 REQEEKKKQEEEEKKKREEEERE--RERERREAELRAQQEEETRKQQELEALQKSQKEAE 873 Query: 82 LKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLK 141 L + Q + VEE ++ + E + + E+ +L+ +RD ++L +L+ Sbjct: 874 LTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRD--QELRRLE 931 Query: 142 KRTQRAIAELI 152 + RA E + Sbjct: 932 EEACRAAQEFL 942 >gi|104526627 triadin [Homo sapiens] Length = 729 Score = 42.4 bits (98), Expect = 2e-04 Identities = 36/135 (26%), Positives = 61/135 (45%), Gaps = 18/135 (13%) Query: 22 GRLEEEALRRKERLKALREKTGR-----------KDKEDGEPKTKHLREEEEEGEKHREL 70 G ++E LR+KE K EK + K+KE G+ K + +E+ E+ H+E Sbjct: 131 GEIDEPPLRKKEIHKDKTEKQEKPERKIQTKVTHKEKEKGKEKVRE-KEKPEKKATHKEK 189 Query: 71 RLRNYVPEDEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPV------IEEVDLANLAPRK 124 + PE + L K + EEK K++++ K E V ++EV P++ Sbjct: 190 IEKKEKPETKTLAKEQKKAKTAEKSEEKTKKEVKGGKQEKVKQTAAKVKEVQKTPSKPKE 249 Query: 125 PDWDLKRDVAKKLEK 139 + K V+K +K Sbjct: 250 KEDKEKAAVSKHEQK 264 Score = 40.4 bits (93), Expect = 8e-04 Identities = 36/156 (23%), Positives = 70/156 (44%), Gaps = 21/156 (13%) Query: 12 GKMEATTAGVGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELR 71 GK T G ++ +A +K+ +K++ KTK E E+ K +E + Sbjct: 353 GKASETKQGTVKIAAQAAAKKD------------EKKEDSKKTKKPAEVEQPKGKKQEKK 400 Query: 72 LRNYVPEDEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKR 131 ++ P K+ VP +++VK + E AK E I V + P K + + Sbjct: 401 EKHVEPAKSPKKEHSVPS------DKQVKAKTERAKEE--IGAVSIKKAVPGKKEEKTTK 452 Query: 132 DVAKKLEKLKKRTQRAIAELIRERLKGQEDSLASAV 167 V +++ K K +I + +E +KG+E+ + +++ Sbjct: 453 TVEQEIRKEKSGKTSSILK-DKEPIKGKEEKVPASL 487 Score = 30.4 bits (67), Expect = 0.85 Identities = 39/163 (23%), Positives = 66/163 (40%), Gaps = 22/163 (13%) Query: 26 EEALRRKERLKALREKTGRKDKED----GEPKTKHLREEEEEGEKHRELRLRNYVP-EDE 80 E+A R AL EK G K K + E K K + +++ EK + + P + Sbjct: 297 EQASRPTPASPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEKKEPGKAS 356 Query: 81 DLKKRRVPQAKPVAVE--------EKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRD 132 + K+ V A A + +K K+ E +P+ +E ++ P K K Sbjct: 357 ETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQEKKEKHVEPAKS--PKKEH 414 Query: 133 VAKKLEKLKKRTQRAIAELIRERLKGQEDSLASAVDAATEQKT 175 +++K +T+RA E+ S+ AV E+KT Sbjct: 415 SVPSDKQVKAKTERAKEEI-------GAVSIKKAVPGKKEEKT 450 >gi|4505101 microtubule-associated protein 7 [Homo sapiens] Length = 749 Score = 42.0 bits (97), Expect = 3e-04 Identities = 37/163 (22%), Positives = 75/163 (46%), Gaps = 11/163 (6%) Query: 17 TTAGVGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYV 76 T+AG EE E+ + RE+ ++++E R E+EE E+ + L V Sbjct: 469 TSAGTTDPEEATRLLAEKRRLAREQREKEERE---------RREQEELERQKREELAQRV 519 Query: 77 PEDEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLK-RDVAK 135 E+ ++ + + +EQL+ E + E + A A R+ + + + R+ A+ Sbjct: 520 AEERTTRREEESRRLEAEQAREKEEQLQRQAEERALREREEAERAQRQKEEEARVREEAE 579 Query: 136 KL-EKLKKRTQRAIAELIRERLKGQEDSLASAVDAATEQKTCD 177 ++ ++ +K QR E + + + +E + AT++KT D Sbjct: 580 RVRQEREKHFQREEQERLERKKRLEEIMKRTRRTEATDKKTSD 622 Score = 39.3 bits (90), Expect = 0.002 Identities = 37/154 (24%), Positives = 70/154 (45%), Gaps = 20/154 (12%) Query: 23 RLEEEALRRKER----LKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPE 78 R E+E L R++R + E+T R+++E + + RE+EE+ ++ E R E Sbjct: 501 RREQEELERQKREELAQRVAEERTTRREEESRRLEAEQAREKEEQLQRQAEERALREREE 560 Query: 79 DEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLE 138 E ++++ +A+ E+V+++ E E ++ RK K+LE Sbjct: 561 AERAQRQKEEEARVREEAERVRQEREKHFQREEQERLE------RK----------KRLE 604 Query: 139 KLKKRTQRAIAELIRERLKGQEDSLASAVDAATE 172 ++ KRT+R A + + D A+ TE Sbjct: 605 EIMKRTRRTEATDKKTSDQRNGDIAKGALTGGTE 638 Score = 26.9 bits (58), Expect = 9.4 Identities = 14/47 (29%), Positives = 25/47 (53%) Query: 23 RLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRE 69 RLEE+ + + R A+ EK ++ +ED E +R E +K ++ Sbjct: 109 RLEEQRQKEERRRAAVEEKRRQRLEEDKERHEAVVRRTMERSQKPKQ 155 >gi|22027541 programmed cell death 7 [Homo sapiens] Length = 485 Score = 42.0 bits (97), Expect = 3e-04 Identities = 39/123 (31%), Positives = 56/123 (45%), Gaps = 15/123 (12%) Query: 33 ERLKALREKT----GRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKKRRVP 88 ERL+ L + R+ E + LRE E E RE V ++++ + RV Sbjct: 221 ERLQPLTQAAYVGEARRRLERVRRRRLRLRERAREREAEREAEAARAVEREQEIDRWRVK 280 Query: 89 QAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKR--DVAKKLEKLKKRTQR 146 + V EEK +EQ A + V+ EV RK D KR D+ + LEKL+K + Sbjct: 281 CVQEV--EEKKREQELKAAADGVLSEV-------RKKQADTKRMVDILRALEKLRKLRKE 331 Query: 147 AIA 149 A A Sbjct: 332 AAA 334 >gi|22758136 MAP7 domain containing 2 [Homo sapiens] Length = 732 Score = 42.0 bits (97), Expect = 3e-04 Identities = 36/154 (23%), Positives = 76/154 (49%), Gaps = 5/154 (3%) Query: 23 RLEEEALRRKERLKALR-EKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDED 81 RLE E L+RK + LR E+ RK +E+ + + + +++E E ++ + E+ Sbjct: 430 RLEREELKRKAEEERLRLEEEARKQEEERKRQEEEKKKQEGEEKRKAGEEAKRKAEEELL 489 Query: 82 LKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLK 141 LK+++ + + A+ EK KE E K V E++ L + + K+++++ Sbjct: 490 LKEKQEQEKQEKAMIEKQKEAAE-TKAREVAEQMRLEREQIMLQIEQERLERKKRIDEIM 548 Query: 142 KRTQRAIAELIRERLKGQEDSLASAVDAATEQKT 175 KRT+++ + ++K ++ + E+KT Sbjct: 549 KRTRKSD---VPPQVKKEDPKVGVQPAVCVEKKT 579 Score = 36.6 bits (83), Expect = 0.012 Identities = 39/162 (24%), Positives = 74/162 (45%), Gaps = 14/162 (8%) Query: 6 KGGAYAGKMEATTAGVGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGE 65 + A GK A T G + L K R L+++ +++ + E + + REE + Sbjct: 382 ENSAALGKPTAGTTDAGEAAK-ILAEKRRQARLQKEQEEQERVEKEEQDRLEREELKRKA 440 Query: 66 KHRELRLRNYVPEDEDLKKRRVPQAKPVAVEEKVKEQLEA---------AKPEPVIEEVD 116 + LRL + E+ +KR+ + K EEK K EA K + E+ + Sbjct: 441 EEERLRLEEEARKQEEERKRQEEEKKKQEGEEKRKAGEEAKRKAEEELLLKEKQEQEKQE 500 Query: 117 LANLAPRKPDWDLK-RDVAKKLEKLKKRTQRAIAELIRERLK 157 A + +K + K R+VA E+++ ++ + ++ +ERL+ Sbjct: 501 KAMIEKQKEAAETKAREVA---EQMRLEREQIMLQIEQERLE 539 Score = 31.6 bits (70), Expect = 0.38 Identities = 35/148 (23%), Positives = 63/148 (42%), Gaps = 10/148 (6%) Query: 6 KGGAYAGKMEATTAGVGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGE 65 K A AG +A +G+ E K L EK + + + + + + +EE++ Sbjct: 372 KHAAAAGGKAENSAALGKPTAGTTDAGEAAKILAEKRRQARLQKEQEEQERVEKEEQDRL 431 Query: 66 KHRELRLRNYVPEDEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKP 125 + EL+ + E+E L+ + + EE+ K Q E K + E+ A RK Sbjct: 432 EREELKRK---AEEERLRLEEEARKQ----EEERKRQEEEKKKQEGEEKRKAGEEAKRKA 484 Query: 126 DWDL---KRDVAKKLEKLKKRTQRAIAE 150 + +L ++ +K EK Q+ AE Sbjct: 485 EEELLLKEKQEQEKQEKAMIEKQKEAAE 512 >gi|41152097 DNA segment on chromosome X and Y (unique) 155 expressed sequence isoform 1 [Homo sapiens] Length = 695 Score = 40.8 bits (94), Expect = 6e-04 Identities = 41/177 (23%), Positives = 84/177 (47%), Gaps = 16/177 (9%) Query: 1 MQDGRKGGAYAGKMEATTAGVGRLEEEALRRKE-------RLKALREKTGRKDKE----- 48 M G G A A ++ + L + ++++++ L+ RE+ R++KE Sbjct: 240 MYKGEDGKAVACNIKVSFDSTKHLSDASIKKRQLERQKLQELEQQREEQKRREKEAEERQ 299 Query: 49 -DGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKKRRVPQAKPVAVEEK-VKEQLEAA 106 E K K L E E E ++ +LR R D +L++ + K A E+K ++E+++ Sbjct: 300 RAEERKQKELEELERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLE 359 Query: 107 KPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKKRTQRAIAELIRERLKGQEDSL 163 + + ++ + +L ++ R L R A KL + +++ ++ + ER + QE L Sbjct: 360 ERKLLLAQRNLQSI--RLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAEL 414 Score = 32.3 bits (72), Expect = 0.22 Identities = 32/118 (27%), Positives = 58/118 (49%), Gaps = 13/118 (11%) Query: 13 KMEATTAGVGRLEEEALRRKERLKALREKTGRKDKEDGE----PKTKHLREEEEEGEKHR 68 K+E A + +E ++ +ER L ++ + + E K LRE+E++ EK Sbjct: 340 KLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQKEEK-- 397 Query: 69 ELRLRNYVPEDEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPD 126 LRL+ + ++RR+ +A+ VEE+ + L + E + E L+ L +KPD Sbjct: 398 -LRLQ------QQEERRRLQEAELRRVEEEKERALGLQRKERELRERLLSILLSKKPD 448 >gi|147903302 MAP7 domain containing 3 [Homo sapiens] Length = 876 Score = 40.8 bits (94), Expect = 6e-04 Identities = 40/141 (28%), Positives = 69/141 (48%), Gaps = 12/141 (8%) Query: 11 AGKMEATTAGVGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHREL 70 AG M A A E L R++R K E+ + ++ K+K + +E G+ L Sbjct: 591 AGIMNAEAATKILTELRRLAREQREKEEEERQREEMQQRVIKKSKDMAKEAVGGQAEDHL 650 Query: 71 RLRNYVPEDEDLKKR----RVPQAKPVAV-EEKVKEQLEAAKPEPVIEEVDLANLAPRKP 125 +L++ ++E KK+ + Q P+ + K+K Q EA K + E + L NL R Sbjct: 651 KLKDGQQQNETKKKKGWLDQEDQEAPLQKGDAKIKAQEEADKRKKEHERIMLQNLQER-- 708 Query: 126 DWDLKRDVAKKLEKLKKRTQR 146 L+R K++E++ KRT++ Sbjct: 709 ---LER--KKRIEEIMKRTRK 724 >gi|117553580 adaptor-related protein complex 3, delta 1 subunit isoform 2 [Homo sapiens] Length = 1153 Score = 40.4 bits (93), Expect = 8e-04 Identities = 48/166 (28%), Positives = 74/166 (44%), Gaps = 26/166 (15%) Query: 23 RLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEG-------EKHRELRLRNY 75 +LEEE R++ K R K ++ ++ G+ + L E +E + E N Sbjct: 726 KLEEERRHRQKLEKDKRRKKRKEKEKKGKRRHSSLPTESDEDIAPAQQVDIVTEEMPENA 785 Query: 76 VPEDEDLKKRRVPQA-------KPVAVEEKVKEQ----LEAAK-PEPVIEEVDLANLAPR 123 +P DED K P KP+A EK+ Q E +K PE + V+ + P+ Sbjct: 786 LPSDEDDKDPNDPYRALDIDLDKPLADSEKLPIQKHRNTETSKSPEKDVPMVEKKSKKPK 845 Query: 124 KPDWDLK---RDVAKKLEKLKKRTQRAIAELIR----ERLKGQEDS 162 K + K RD KK EK KK++ + + R ER KG++ S Sbjct: 846 KKEKKHKEKERDKEKKKEKEKKKSPKPKKKKHRKEKEERTKGKKKS 891 Score = 28.9 bits (63), Expect = 2.5 Identities = 33/153 (21%), Positives = 62/153 (40%), Gaps = 13/153 (8%) Query: 30 RRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKKRRVPQ 89 R E K+ + +K+ +PK K + +E+E +K ++ KK R + Sbjct: 822 RNTETSKSPEKDVPMVEKKSKKPKKKEKKHKEKERDKEKKKEKEKKKSPKPKKKKHRKEK 881 Query: 90 AKPVAVEEKVKEQ---LEAAKPEPVIEEVDLANLAPRKPDWDLKRD------VAKKLEKL 140 + ++K K+Q E A EPV P + + L + L Sbjct: 882 EERTKGKKKSKKQPPGSEEAAGEPVQNGAPEEEQLPPESSYSLLAENSYVKMTCDIRGSL 941 Query: 141 KKRTQRAIAELIRER----LKGQEDSLASAVDA 169 ++ +Q +A ++ R LKG E S+ +++A Sbjct: 942 QEDSQVTVAIVLENRSSSILKGMELSVLDSLNA 974 Score = 28.9 bits (63), Expect = 2.5 Identities = 20/89 (22%), Positives = 43/89 (48%), Gaps = 10/89 (11%) Query: 21 VGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDE 80 V +E+++ + K++ K +EK K+K+ + K K + ++++ K +E E Sbjct: 834 VPMVEKKSKKPKKKEKKHKEKERDKEKKKEKEKKKSPKPKKKKHRKEKE----------E 883 Query: 81 DLKKRRVPQAKPVAVEEKVKEQLEAAKPE 109 K ++ + +P EE E ++ PE Sbjct: 884 RTKGKKKSKKQPPGSEEAAGEPVQNGAPE 912 >gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 668 Score = 40.0 bits (92), Expect = 0.001 Identities = 30/150 (20%), Positives = 78/150 (52%), Gaps = 14/150 (9%) Query: 23 RLEEEALRRKERLKALREKTGRKDK----EDGEPKTKHLREEEEEGEKH-----RELRLR 73 RLEE ++E+++ L EK ++K E+ + + +RE+E+ E+ +E ++R Sbjct: 367 RLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIR 426 Query: 74 NYVPEDEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDV 133 + + +K+ Q + + +EK++E+ + + E + + + + ++ W K + Sbjct: 427 EQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEE--KIREQEEIWRQKEKM 484 Query: 134 AKKLEKLKKRTQRAIAELIRERLKGQEDSL 163 ++ EK++K+ ++ + E++ QE+ + Sbjct: 485 HEQ-EKIRKQEEKVWRQ--EEKMHDQEEKI 511 Score = 39.3 bits (90), Expect = 0.002 Identities = 36/158 (22%), Positives = 73/158 (46%), Gaps = 21/158 (13%) Query: 23 RLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDL 82 R EE+ +E+++ EK ++++ E + K R+EE EK ++R + + +++ Sbjct: 304 RQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 363 Query: 83 KKRRVPQ------------AKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLK 130 K RR+ + + + +EK++EQ E + E I E + K W + Sbjct: 364 KMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKM-WRQE 422 Query: 131 RDVAKKLEKLKKRTQRA--------IAELIRERLKGQE 160 + ++ EK++++ ++ E IRE K QE Sbjct: 423 EKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQE 460 Score = 38.9 bits (89), Expect = 0.002 Identities = 28/135 (20%), Positives = 67/135 (49%), Gaps = 3/135 (2%) Query: 13 KMEATTAGVGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRL 72 KM + EE+ R++E+++ EK ++++ E + +EE+ GE+ +++ Sbjct: 503 KMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQE 562 Query: 73 RNYVPEDEDLKKRRVPQAKPVAVEEKVKEQLEAA-KPEPVIEEVDLANLAPRKPDWDLKR 131 + + E+ K R + K +EK++EQ E + E I E + + W+ + Sbjct: 563 QEKMRRQEE--KIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEE 620 Query: 132 DVAKKLEKLKKRTQR 146 + ++ EK++++ ++ Sbjct: 621 KMCEQEEKMQEQEEK 635 Score = 35.0 bits (79), Expect = 0.034 Identities = 31/154 (20%), Positives = 74/154 (48%), Gaps = 10/154 (6%) Query: 21 VGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDE 80 + + EE+ R++E++ EK ++++ + K +EE+ E+ ++R E E Sbjct: 490 IRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIR------EQE 543 Query: 81 DLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKL 140 ++ + + + K EEK++EQ + + E I E + ++ + + + ++ EK+ Sbjct: 544 EMMQEQ--EEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKI 601 Query: 141 KKRTQRAIAELIRERLKGQEDSLASAVDAATEQK 174 R Q + + E++ QE+ + + EQ+ Sbjct: 602 --REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQE 633 Score = 29.6 bits (65), Expect = 1.4 Identities = 31/150 (20%), Positives = 73/150 (48%), Gaps = 26/150 (17%) Query: 23 RLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDL 82 R +EE ++ +E EK G ++ E + + K R+EE+ E+ ++R E Sbjct: 540 REQEEMMQEQE------EKMGEQE-EKMQEQEKMRRQEEKIREQEEKIR--------EQK 584 Query: 83 KKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKK 142 +K R + K EEK++EQ E +++E + + + + + ++ EK+++ Sbjct: 585 EKIREQEEKIWEQEEKIREQ------EEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRR 638 Query: 143 RTQRAIAELIR-----ERLKGQEDSLASAV 167 + ++ + +R E+++ ++ L +A+ Sbjct: 639 QEEKMWEQEVRLRQQEEKMQEHQEHLEAAI 668 Score = 27.3 bits (59), Expect = 7.2 Identities = 20/90 (22%), Positives = 42/90 (46%), Gaps = 8/90 (8%) Query: 13 KMEATTAGVGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRL 72 KM + EE+ +KE+++ EK ++++ E + +EE+ E+ ++ Sbjct: 565 KMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCE 624 Query: 73 RNYVPEDEDLKKRRVPQAKPVAVEEKVKEQ 102 + ++++ K RR EEK+ EQ Sbjct: 625 QEEKMQEQEEKMRR--------QEEKMWEQ 646 >gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] Length = 275 Score = 40.0 bits (92), Expect = 0.001 Identities = 41/148 (27%), Positives = 65/148 (43%), Gaps = 24/148 (16%) Query: 30 RRKERLKALREKTGRKDKEDG--EPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKKRRV 87 R KER K +EK R+ K+ G E K K R+E E K R R R KKRR Sbjct: 90 REKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKR---------KKRRK 140 Query: 88 PQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKKRTQRA 147 + + EK + + E + + +K + + KR+ +K E+ K+R ++ Sbjct: 141 KKRRKERKREKERGKRERKRKK------------RKKEEREKKRERNRK-ERKKERERKE 187 Query: 148 IAELIRERLKGQEDSLASAVDAATEQKT 175 E +ER K + D T+++T Sbjct: 188 RRERKKERKKERRKKKERKKDRKTDRQT 215 Score = 38.1 bits (87), Expect = 0.004 Identities = 34/139 (24%), Positives = 64/139 (46%), Gaps = 13/139 (9%) Query: 23 RLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDL 82 R E R+ER K RE+ + +E G+ + K ++ E E+ R+ + R ++ Sbjct: 32 RESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKER-----EKQR 86 Query: 83 KKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKK 142 K+RR + + E+K +E+ + + E ++ K + KR KK K K+ Sbjct: 87 KERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKR---KKRRKKKR 143 Query: 143 RTQRAIAELIRERLKGQED 161 R +R RE+ +G+ + Sbjct: 144 RKERK-----REKERGKRE 157 Score = 35.8 bits (81), Expect = 0.020 Identities = 32/133 (24%), Positives = 61/133 (45%), Gaps = 3/133 (2%) Query: 26 EEALRRKERLKALREKTGRKDKEDGEPKT--KHLREEEEEGEKHRELRLRNYVPEDEDLK 83 E R++ER K + + G+K+K+ + + K + +E EK R+ R + + K Sbjct: 42 EREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEK 101 Query: 84 KRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAK-KLEKLKK 142 K+R + + +K KE+ E + E +K + KR+ + K E+ +K Sbjct: 102 KKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRK 161 Query: 143 RTQRAIAELIRER 155 + ++ E RER Sbjct: 162 KRKKEEREKKRER 174 Score = 32.3 bits (72), Expect = 0.22 Identities = 26/88 (29%), Positives = 46/88 (52%), Gaps = 6/88 (6%) Query: 22 GRLEEEALR-RKERLKALREKTGRKDKEDGEPK-TKHLREEEEEGEKHRELRLRNYVPED 79 GR E + + RKER + +++ RK K+ + K K + E+E G++ R+ + R + Sbjct: 110 GRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKR----KK 165 Query: 80 EDLKKRRVPQAKPVAVEEKVKEQLEAAK 107 E+ +K+R K E + KE+ E K Sbjct: 166 EEREKKRERNRKERKKERERKERRERKK 193 Score = 30.8 bits (68), Expect = 0.65 Identities = 26/119 (21%), Positives = 57/119 (47%), Gaps = 9/119 (7%) Query: 25 EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKK 84 E++ RK+R + RE+ +K++++ E + K RE + + + ++ R ++ ++ Sbjct: 100 EKKKRERKQRGR--RERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRE 157 Query: 85 RRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKKR 143 R+ + K E+K + + K E +E R+ + K++ KK E+ K R Sbjct: 158 RKRKKRKKEEREKKRERNRKERKKERERKE-------RRERKKERKKERRKKKERKKDR 209 >gi|88759339 aster-associated protein [Homo sapiens] Length = 647 Score = 40.0 bits (92), Expect = 0.001 Identities = 39/151 (25%), Positives = 66/151 (43%), Gaps = 9/151 (5%) Query: 26 EEALRRKERLKALREKTGRK--DKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLK 83 EEAL E KA++EK +K K+ E K K EEE K L+ E K Sbjct: 467 EEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKTEEENAARKGEALQ------AFEKWK 520 Query: 84 KRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKKR 143 ++++ K +E+ E+ + K E + E NL + W+ K++ K ++ +K Sbjct: 521 EKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVE-KWNEKKEAFFKQKEKEKI 579 Query: 144 TQRAIAELIRERLKGQEDSLASAVDAATEQK 174 ++ EL R K ++ + + E K Sbjct: 580 NEKRKEELKRAEKKDKDKQAINEYEKWLENK 610 >gi|149589021 doublecortin-like kinase 3 [Homo sapiens] Length = 648 Score = 39.7 bits (91), Expect = 0.001 Identities = 44/170 (25%), Positives = 75/170 (44%), Gaps = 18/170 (10%) Query: 11 AGKMEATTAGVGRLEEEALR--RKERLKALREKTGR---KDKEDGEPKTKHLREEEEEGE 65 A K + V + EE LR +K+ R K G ++ + G K + R EE+E E Sbjct: 239 AAKAKKDLVEVLPVTEEGLREVKKDTRPMSRSKHGGWLLREHQAGFEKLRRTRGEEKEAE 298 Query: 66 KHRELRL----RNYVPEDEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLA 121 K ++ + R + +D+ K + P+ +P EE E+ KP P+ + AN+ Sbjct: 299 KEKKPCMSGGRRMTLRDDQPAKLEKEPKTRP---EENKPERPSGRKPRPM--GIIAANVE 353 Query: 122 PRKPDWDLKRD----VAKKLEKLKKRTQRAIAELIRERLKGQEDSLASAV 167 + D V K+ + R A+ + + RLKG+ED + S + Sbjct: 354 KHYETGRVIGDGNFAVVKECRHRETRQAYAMKIIDKSRLKGKEDMVDSEI 403 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.307 0.128 0.342 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 7,271,167 Number of Sequences: 37866 Number of extensions: 378911 Number of successful extensions: 6059 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 280 Number of HSP's successfully gapped in prelim test: 546 Number of HSP's that attempted gapping in prelim test: 2980 Number of HSP's gapped (non-prelim): 2312 length of query: 179 length of database: 18,247,518 effective HSP length: 96 effective length of query: 83 effective length of database: 14,612,382 effective search space: 1212827706 effective search space used: 1212827706 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.6 bits) S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.