Guide to the Human Genome
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Search of human proteins with 238231397

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|238231397 coiled-coil domain containing 12 [Homo sapiens]
         (179 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|238231397 coiled-coil domain containing 12 [Homo sapiens]          352   7e-98
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap...    52   3e-07
gi|221219020 NYD-SP11 protein [Homo sapiens]                           51   5e-07
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]             50   8e-07
gi|4503509 eukaryotic translation initiation factor 3, subunit 1...    49   2e-06
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa...    47   1e-05
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]            47   1e-05
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi...    44   7e-05
gi|102467235 inner centromere protein antigens 135/155kDa isofor...    44   7e-05
gi|102467242 inner centromere protein antigens 135/155kDa isofor...    44   7e-05
gi|12711674 UPF3 regulator of nonsense transcripts homolog B iso...    44   1e-04
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap...    43   2e-04
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap...    43   2e-04
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap...    43   2e-04
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi...    43   2e-04
gi|148746195 trichohyalin [Homo sapiens]                               43   2e-04
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li...    42   2e-04
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li...    42   2e-04
gi|154354979 myosin X [Homo sapiens]                                   42   2e-04
gi|104526627 triadin [Homo sapiens]                                    42   2e-04
gi|4505101 microtubule-associated protein 7 [Homo sapiens]             42   3e-04
gi|22027541 programmed cell death 7 [Homo sapiens]                     42   3e-04
gi|22758136 MAP7 domain containing 2 [Homo sapiens]                    42   3e-04
gi|41152097 DNA segment on chromosome X and Y (unique) 155 expre...    41   6e-04
gi|147903302 MAP7 domain containing 3 [Homo sapiens]                   41   6e-04
gi|117553580 adaptor-related protein complex 3, delta 1 subunit ...    40   8e-04
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa...    40   0.001
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]            40   0.001
gi|88759339 aster-associated protein [Homo sapiens]                    40   0.001
gi|149589021 doublecortin-like kinase 3 [Homo sapiens]                 40   0.001

>gi|238231397 coiled-coil domain containing 12 [Homo sapiens]
          Length = 179

 Score =  352 bits (904), Expect = 7e-98
 Identities = 179/179 (100%), Positives = 179/179 (100%)

Query: 1   MQDGRKGGAYAGKMEATTAGVGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREE 60
           MQDGRKGGAYAGKMEATTAGVGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREE
Sbjct: 1   MQDGRKGGAYAGKMEATTAGVGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREE 60

Query: 61  EEEGEKHRELRLRNYVPEDEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANL 120
           EEEGEKHRELRLRNYVPEDEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANL
Sbjct: 61  EEEGEKHRELRLRNYVPEDEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANL 120

Query: 121 APRKPDWDLKRDVAKKLEKLKKRTQRAIAELIRERLKGQEDSLASAVDAATEQKTCDSD 179
           APRKPDWDLKRDVAKKLEKLKKRTQRAIAELIRERLKGQEDSLASAVDAATEQKTCDSD
Sbjct: 121 APRKPDWDLKRDVAKKLEKLKKRTQRAIAELIRERLKGQEDSLASAVDAATEQKTCDSD 179


>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
           sapiens]
          Length = 570

 Score = 52.0 bits (123), Expect = 3e-07
 Identities = 38/157 (24%), Positives = 83/157 (52%), Gaps = 7/157 (4%)

Query: 23  RLEEEALRRKERLKALREKTGRKDKE---DGEPKTKHLREEEEEGEKHRELRLRNYVPED 79
           R +EE +RR+E +   +E+  R+ +E   + E K + L E+  E EK RE   +    E 
Sbjct: 312 REQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEK 371

Query: 80  -EDLKKRRVPQAKPVAVEEKVKEQLEAAK-PEPVIEEVDLANLAPRKPDWDLKRDVAKKL 137
             + +KR+  +AK    EEK++EQ E  +  E +++E +       +  W+ + ++ ++ 
Sbjct: 372 IREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQE 431

Query: 138 EKLKKRTQRAIAELIRERLKGQEDSLASAVDAATEQK 174
           EK++++ ++   +   ++++ QE+ +    +   EQ+
Sbjct: 432 EKMRRQEEKIREQ--EKKIREQEEKIREQEEMMQEQE 466



 Score = 44.7 bits (104), Expect = 4e-05
 Identities = 35/150 (23%), Positives = 75/150 (50%), Gaps = 5/150 (3%)

Query: 25  EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKK 84
           EE+  R++E+++   EK   ++++  E + K  R+EE   EK  ++R +  +  +++ K 
Sbjct: 287 EEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKI 346

Query: 85  RRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKKRT 144
           R + +   +  +EK++EQ E  + E  I E +       K  W  +  + ++ EK+  R 
Sbjct: 347 RELEE--KMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKM-WRQEEKIREQEEKI--RE 401

Query: 145 QRAIAELIRERLKGQEDSLASAVDAATEQK 174
           Q  + +   E++  QE+ +    +   EQ+
Sbjct: 402 QEEMMQEQEEKMGEQEEKMWEQEEEMQEQE 431



 Score = 40.4 bits (93), Expect = 8e-04
 Identities = 34/169 (20%), Positives = 77/169 (45%), Gaps = 11/169 (6%)

Query: 13  KMEATTAGVGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRL 72
           K +   A + R EE+   ++E+++   E    ++++ GE + K   +EEE  E+  ++R 
Sbjct: 377 KRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRR 436

Query: 73  RNYVPEDEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRD 132
           +         +K R  + K    EEK++EQ E  + +          +  ++     + +
Sbjct: 437 QE--------EKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEE 488

Query: 133 VAKKLEKLKKRTQRAIAELIRERLKGQEDSLASAVDAATEQ--KTCDSD 179
             ++ E+  +  ++ I E   E+++ QE+ +    +   EQ  K C+ +
Sbjct: 489 KMRRQEEKIREQEKKIREQ-EEKIREQEEMMQEQEEKMWEQEEKMCEQE 536



 Score = 39.3 bits (90), Expect = 0.002
 Identities = 36/146 (24%), Positives = 76/146 (52%), Gaps = 15/146 (10%)

Query: 25  EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEE-GEKHRELRLRNYVPEDEDLK 83
           +EE +RR+E     +EK  R+ +E    + + ++E+EE+ GE+  ++  +    ++++ K
Sbjct: 430 QEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEK 489

Query: 84  KRRVPQAKPVAVEEKVKEQ-LEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKK 142
            RR         EEK++EQ  +  + E  I E +       +  W+ +  + ++ EK+++
Sbjct: 490 MRR--------QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 541

Query: 143 RTQ--RAIAELIRE---RLKGQEDSL 163
           + +  R   E +RE   RL+ QE+ +
Sbjct: 542 QEEKMRRQEEKMREQEVRLRQQEEKM 567



 Score = 32.0 bits (71), Expect = 0.29
 Identities = 23/97 (23%), Positives = 48/97 (49%), Gaps = 8/97 (8%)

Query: 6   KGGAYAGKMEATTAGVGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGE 65
           K G   GKM    A +   EE+  R++E+++   +K   ++++  E +     +EE+  E
Sbjct: 468 KMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWE 527

Query: 66  KHRELRLRNYVPEDEDLKKRRVPQAKPVAVEEKVKEQ 102
           +  ++  +    ++++ K RR         EEK++EQ
Sbjct: 528 QEEKMCEQEEKMQEQEEKMRR--------QEEKMREQ 556


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score = 51.2 bits (121), Expect = 5e-07
 Identities = 39/140 (27%), Positives = 72/140 (51%), Gaps = 3/140 (2%)

Query: 26   EEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKKR 85
            E  L   E+ ++L  +   + +E+ E + + +REEEEE ++  E   +    E+E+ KK+
Sbjct: 2231 ESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKK 2290

Query: 86   RVPQAK-PVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKKRT 144
            +  + K  V  +E+V E+ E    E   E   L++    +    L+ +V ++ E LKK  
Sbjct: 2291 KKEKKKEEVQEKEEVFEEKEEIMSEE--ETESLSDEEEEEESCSLEEEVDREKEILKKEK 2348

Query: 145  QRAIAELIRERLKGQEDSLA 164
            Q  + E  R+ L+G+E  L+
Sbjct: 2349 QFKLQEQRRKSLRGRERVLS 2368



 Score = 32.7 bits (73), Expect = 0.17
 Identities = 44/175 (25%), Positives = 77/175 (44%), Gaps = 20/175 (11%)

Query: 2    QDGRKGGAYAGKMEATTAGVGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEE 61
            QD R+     GK         + EE   +R E+L    EK  +K K+  +   K  REEE
Sbjct: 1625 QDDREMAQAEGKF-------AQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEE 1677

Query: 62   EEGEKHREL-RLRNYVPEDEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANL 120
            +  +K  +L  ++N + +    K   +PQ      E+ +  Q +    E    E D+  L
Sbjct: 1678 KLAKKGGKLAEVKNILAQ----KVEELPQR-----EQNLDWQEKELAQELEELEWDMEEL 1728

Query: 121  APRKPDWDLKRDVAKKLEKLKKRTQRAIA-ELIRERLKGQEDSLASAVDAATEQK 174
            + ++   +L ++  K +E+ KK  +   A    RE+L  +E  LA   +   ++K
Sbjct: 1729 SWKEE--ELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEK 1781



 Score = 30.4 bits (67), Expect = 0.85
 Identities = 43/182 (23%), Positives = 80/182 (43%), Gaps = 25/182 (13%)

Query: 1    MQDGRKGGAYAGKMEATTAGVGRLEEEALRRKERLKALREK--------TGRK----DKE 48
            +Q+  K   +  KM      +GR  E+ + +K +L   RE+        T  K     K+
Sbjct: 1778 IQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKK 1837

Query: 49   DGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKKRRVPQAKPV-----AVEEKVKEQL 103
            +   + K+L +E+E+  + +E  L  Y  E     K+++ Q K        +  +V+E+L
Sbjct: 1838 NLAQEKKNLAQEKEKLAQRKENLL--YNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKL 1895

Query: 104  EAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKKRTQRAIAELI----RERLKGQ 159
               K   + ++  LA     K    ++  +AKK EKL +   +   E      ++RL+G+
Sbjct: 1896 TQEKETVIKKKEKLAE--TEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGE 1953

Query: 160  ED 161
             D
Sbjct: 1954 LD 1955



 Score = 29.3 bits (64), Expect = 1.9
 Identities = 39/163 (23%), Positives = 74/163 (45%), Gaps = 22/163 (13%)

Query: 25   EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHREL---RLRNYVPEDED 81
            +E+  + KE++    E+ GRK ++  E K K  ++ E       EL   ++  Y  ++  
Sbjct: 1781 KEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLA 1840

Query: 82   LKKRRVPQAKPVAVEEKV-----KEQLEAAKPE--PVIEEVDLANLAPRKPDWDL---KR 131
             +K+ + Q K    + K      KE+L  +K +   V  ++ + N    + +  L   K 
Sbjct: 1841 QEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKE 1900

Query: 132  DVAKKLEKLKKRTQRAIAELIRERLKGQEDSLASAVDAATEQK 174
             V KK EKL + T++ + ++        EDSLA   +   ++K
Sbjct: 1901 TVIKKKEKLAE-TEKKLVQV--------EDSLAKKQEKLAQEK 1934



 Score = 28.9 bits (63), Expect = 2.5
 Identities = 30/126 (23%), Positives = 60/126 (47%), Gaps = 14/126 (11%)

Query: 25   EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELR------LRNYVPE 78
            E+  ++ + +   +  K  R +K+  + + K  +EEE+  ++ R+L        + YV  
Sbjct: 1564 EQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKI 1623

Query: 79   DEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLK-RDVAKKL 137
             +D   R + QA+    +   KE+  A + E + +E +   LA ++     K   VA++ 
Sbjct: 1624 TQD--DREMAQAEGKFAQ---KEETLAQRGEKLSQEAE--KLAQKRKKLAKKWEKVAREE 1676

Query: 138  EKLKKR 143
            EKL K+
Sbjct: 1677 EKLAKK 1682


>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
          Length = 2817

 Score = 50.4 bits (119), Expect = 8e-07
 Identities = 42/161 (26%), Positives = 76/161 (47%), Gaps = 13/161 (8%)

Query: 23  RLEEEALRR-KERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRL---RNYVPE 78
           R+EE+      E+LK L EK G  +K   +P  + +RE E E E+ RE  L   +    E
Sbjct: 472 RMEEQRKAACAEKLKRLDEKLGILEK---QPSPEEIREREREKEREREKELEKEQEQERE 528

Query: 79  DEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLE 138
            E  K R   Q K   +E++ ++Q E  K     +E +L     ++ +    ++  K+ E
Sbjct: 529 KEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECE 588

Query: 139 KLKKRTQRAIAELIRERLKGQEDSLASAVDAATEQKTCDSD 179
             K+R      E + E+++ +E +L   V+    + +C+ +
Sbjct: 589 LEKER------EKLEEKIEPREPNLEPMVEKQESENSCNKE 623



 Score = 42.0 bits (97), Expect = 3e-04
 Identities = 45/170 (26%), Positives = 80/170 (47%), Gaps = 35/170 (20%)

Query: 1   MQDGRKGGAYAGKMEATTAGVGRLEE----EALRRKERLKAL-------------REKTG 43
           M++ RK  A A K++     +G LE+    E +R +ER K               REK  
Sbjct: 473 MEEQRKA-ACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKER 531

Query: 44  RKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKKRR---------VPQAKPVA 94
            KD+E  + K K L   E+E EK RE+       ++++L++++           Q K   
Sbjct: 532 EKDRERQQEKEKEL---EKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECE 588

Query: 95  VE---EKVKEQLEAAKP--EPVIEEVDLANLAPRKPDWDLKRDVAKKLEK 139
           +E   EK++E++E  +P  EP++E+ +  N   ++ +    R  + + EK
Sbjct: 589 LEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEK 638


>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
           theta, 150/170kDa [Homo sapiens]
          Length = 1382

 Score = 48.9 bits (115), Expect = 2e-06
 Identities = 41/137 (29%), Positives = 71/137 (51%), Gaps = 23/137 (16%)

Query: 31  RKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKKRRVPQA 90
           RKERL++L  +  +++ E  E + + +R+ EEE       RLR    E ++ +K R+ Q 
Sbjct: 578 RKERLESLNIQREKEELEQREAELQKVRKAEEE-------RLRQ---EAKEREKERILQE 627

Query: 91  KPVAVEEKVKEQLEAAKPEPV----IEEVDLANLAPRKPDWDLKRDVAKKLEKLKKRTQR 146
                ++ V+E+LE  K   +     +++D+ +L    PD+ + + V ++LEK KK  Q 
Sbjct: 628 HEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQV-EQLEKEKKELQ- 685

Query: 147 AIAELIRERLKGQEDSL 163
                  ERLK QE  +
Sbjct: 686 -------ERLKNQEKKI 695



 Score = 31.6 bits (70), Expect = 0.38
 Identities = 40/159 (25%), Positives = 67/159 (42%), Gaps = 30/159 (18%)

Query: 21  VGRLEEEALRRKERLKALREKTGRKDK--------------EDGEPKTKHLREEEEEG-- 64
           V +LE+E    +ERLK   +K    ++              E+   K   L E++EE   
Sbjct: 674 VEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERI 733

Query: 65  -----EKHRELRLRNYVP---EDEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVD 116
                E+ + L  +N +    ED DL   R+  A+    EEK+K+       E  + E  
Sbjct: 734 TTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQF------EERLAEER 787

Query: 117 LANLAPRKPDWDLKRDVAKKLEKLKKRTQRAIAELIRER 155
              L  RK     +R +    EK ++  +RA  ++++ER
Sbjct: 788 HNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKER 826



 Score = 30.0 bits (66), Expect = 1.1
 Identities = 29/108 (26%), Positives = 47/108 (43%), Gaps = 5/108 (4%)

Query: 23  RLEEEALRRKE--RLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDE 80
           RLEE   +RKE  R+   REK   +++E    + + L+E EE     R  R        E
Sbjct: 790 RLEERKRQRKEERRITYYREK---EEEEQRRAEEQMLKEREERERAERAKREEELREYQE 846

Query: 81  DLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWD 128
            +KK    + K    E +++E+    + E  + +  L+    R  D D
Sbjct: 847 RVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWGDRD 894



 Score = 28.1 bits (61), Expect = 4.2
 Identities = 25/93 (26%), Positives = 44/93 (47%), Gaps = 11/93 (11%)

Query: 23  RLEEEALRRKERLKALREKTGR------KDKEDGEPKTKHLREEEEEGEK----HRELRL 72
           RL EE   R E  K  R++  R      K++E+     + + +E EE E+     RE  L
Sbjct: 782 RLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEEL 841

Query: 73  RNYVPEDEDLKK-RRVPQAKPVAVEEKVKEQLE 104
           R Y    + L++  R  + + + +EE+ + + E
Sbjct: 842 REYQERVKKLEEVERKKRQRELEIEERERRREE 874



 Score = 27.3 bits (59), Expect = 7.2
 Identities = 21/78 (26%), Positives = 35/78 (44%), Gaps = 2/78 (2%)

Query: 15  EATTAGVGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEE--GEKHRELRL 72
           E   A   + EEE    +ER+K L E   +K + + E + +  R EEE   G+     + 
Sbjct: 828 ERERAERAKREEELREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLSRKD 887

Query: 73  RNYVPEDEDLKKRRVPQA 90
             +   D +   R+ P+A
Sbjct: 888 SRWGDRDSEGTWRKGPEA 905


>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 750

 Score = 46.6 bits (109), Expect = 1e-05
 Identities = 38/170 (22%), Positives = 83/170 (48%), Gaps = 9/170 (5%)

Query: 13  KMEATTAGVGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRL 72
           KM      + + EE+  R++E+++   EK  R+ +E    + + +RE+EE   +  ++  
Sbjct: 497 KMHEQEEKIRKQEEKVWRQEEKIREQEEKI-REQEEKMWRQEEKIREQEEMWREEEKMHE 555

Query: 73  RNYVPEDEDLKKRRVPQAKPVAVEEKVKEQLEAA-KPEPVIEEVDLANLAPRKPDWDLKR 131
           +  + E+E   KR+  + K    EEK++EQ E   + E  I E +       +  W  + 
Sbjct: 556 QEKIWEEE---KRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEE 612

Query: 132 DVAKKLEKLKKRTQRAIAELIRERLKGQEDSLASAVDAATEQ--KTCDSD 179
            + ++ EK++++ ++   +   E+++ QE+      +   EQ  K C+ +
Sbjct: 613 KIREQEEKIQEQEEKIREQ--EEKIREQEEMTQEQEEKMGEQEEKMCEQE 660



 Score = 39.7 bits (91), Expect = 0.001
 Identities = 36/156 (23%), Positives = 72/156 (46%), Gaps = 21/156 (13%)

Query: 25  EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKK 84
           EE+   ++E+++   EK  R+++   E + K  R+EE   EK  ++R +  +  +++ K 
Sbjct: 320 EEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM 379

Query: 85  RRVPQ------------AKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRD 132
           RR  +             + +  +EK++EQ E  + E  I E +       K  W  +  
Sbjct: 380 RRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKM-WRQEEK 438

Query: 133 VAKKLEKLKKRTQRA--------IAELIRERLKGQE 160
           + ++ EK++++ ++           E IRE  K QE
Sbjct: 439 IREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQE 474



 Score = 38.9 bits (89), Expect = 0.002
 Identities = 37/155 (23%), Positives = 77/155 (49%), Gaps = 19/155 (12%)

Query: 25  EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEE---------EGEKHRELRLRNY 75
           +EE +RR+E +   +E+  R+ +E    + K +RE+EE         E EK +E   + +
Sbjct: 375 KEEKMRRQEEMMWEKEEKIRELEEKMHEQEK-IREQEEKRQEEEKIREQEKRQEQEAKMW 433

Query: 76  VPED---EDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDL----ANLAPRKPDWD 128
             E+   E  +K R  + K    EEK+ EQ +  + E   E+ ++      +  ++  W 
Sbjct: 434 RQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWR 493

Query: 129 LKRDVAKKLEKLKKRTQRAIAELIRERLKGQEDSL 163
            K  + ++ EK++K+ ++   +   E+++ QE+ +
Sbjct: 494 QKEKMHEQEEKIRKQEEKVWRQ--EEKIREQEEKI 526



 Score = 38.1 bits (87), Expect = 0.004
 Identities = 35/144 (24%), Positives = 72/144 (50%), Gaps = 4/144 (2%)

Query: 23  RLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDL 82
           R EE+    +E+++   EK   ++++  E + K  R+EE   EK  ++R +  +  +++ 
Sbjct: 304 RQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 363

Query: 83  KKRRVPQAKPVAVEEKVKEQLEA--AKPEPVIEEVDLANLAPRKPDWDLKRDVAKKL-EK 139
           K RR  +      EEK++ Q E    K E + E  +  +   +  + + KR   +K+ E+
Sbjct: 364 KMRR-QEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ 422

Query: 140 LKKRTQRAIAELIRERLKGQEDSL 163
            K++ Q A      E+++ QE+ +
Sbjct: 423 EKRQEQEAKMWRQEEKIREQEEKI 446



 Score = 37.0 bits (84), Expect = 0.009
 Identities = 32/153 (20%), Positives = 73/153 (47%), Gaps = 8/153 (5%)

Query: 25  EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEE---EEGEKHRELRLRNYVPEDED 81
           E+E +  +E+ +   +K  R++++  E + K  R+EE   E+ EK +E   + +  E+  
Sbjct: 555 EQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEE-- 612

Query: 82  LKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLK 141
             K R  + K    EEK++EQ E  + +  + +     +  ++     + +  ++ E+  
Sbjct: 613 --KIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETM 670

Query: 142 KRTQRAIAELIRERLKGQEDSLASAVDAATEQK 174
            R +  I E   ++++ QE+ +    +   EQ+
Sbjct: 671 WRQEEKIREQ-EKKIREQEEKIREQEEMMQEQE 702



 Score = 36.6 bits (83), Expect = 0.012
 Identities = 29/157 (18%), Positives = 74/157 (47%), Gaps = 11/157 (7%)

Query: 25  EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKK 84
           E++  R++E+++   EK  R++++  E + K   +EE+  ++  ++R +    ++++ K 
Sbjct: 569 EDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKI 628

Query: 85  RRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKKRT 144
           R          EEK++EQ E  + +          +  ++     + +   + E+  +  
Sbjct: 629 REQ--------EEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQ 680

Query: 145 QRAIAELIRERLKGQEDSLASAVDAATEQ--KTCDSD 179
           ++ I E   E+++ QE+ +    +   EQ  K C+ +
Sbjct: 681 EKKIREQ-EEKIREQEEMMQEQEEKMWEQEEKMCEQE 716



 Score = 35.4 bits (80), Expect = 0.026
 Identities = 31/155 (20%), Positives = 78/155 (50%), Gaps = 4/155 (2%)

Query: 21  VGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDE 80
           V R EE+   ++E+ +   EK  +++++  E + K   +EE+  E+  ++R +  + +++
Sbjct: 586 VWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQ 645

Query: 81  DLKKRRVPQAKPVAVEEKVKEQLEAA-KPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEK 139
           + +K    + K    EEK++EQ E   + E  I E +       +   + +  + ++ EK
Sbjct: 646 E-EKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEK 704

Query: 140 LKKRTQRAIAELIRERLKGQEDSLASAVDAATEQK 174
           + ++ ++   +   E+++ QE+ +    +   EQ+
Sbjct: 705 MWEQEEKMCEQ--EEKMQEQEEKMRRQEEKMWEQE 737



 Score = 33.9 bits (76), Expect = 0.077
 Identities = 34/160 (21%), Positives = 70/160 (43%), Gaps = 12/160 (7%)

Query: 25  EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKK 84
           EEE  + +E +    EK   +++   + +  H +EE+   ++ +  R    + E E+  K
Sbjct: 468 EEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEE--K 525

Query: 85  RRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPD-----WDLKRDVAKKLEK 139
            R  + K    EEK++EQ E  + E  + E +      ++ +     W  +  + ++ EK
Sbjct: 526 IREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEK 585

Query: 140 L-----KKRTQRAIAELIRERLKGQEDSLASAVDAATEQK 174
           +     K R Q    +   E++  QE+ +    +   EQ+
Sbjct: 586 VWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQE 625



 Score = 32.0 bits (71), Expect = 0.29
 Identities = 30/153 (19%), Positives = 74/153 (48%), Gaps = 4/153 (2%)

Query: 23  RLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDL 82
           R EE+   ++E++    EK   ++++  E + K  ++EE+  E+  +++ +     +++ 
Sbjct: 574 RQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQE- 632

Query: 83  KKRRVPQAKPVAVEEKVKEQLE-AAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLK 141
           +K R  +      EEK+ EQ E   + E  ++E +       +   + ++ + ++ EK+ 
Sbjct: 633 EKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKI- 691

Query: 142 KRTQRAIAELIRERLKGQEDSLASAVDAATEQK 174
            R Q  + +   E++  QE+ +    +   EQ+
Sbjct: 692 -REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQE 723



 Score = 28.5 bits (62), Expect = 3.2
 Identities = 21/121 (17%), Positives = 58/121 (47%), Gaps = 1/121 (0%)

Query: 23  RLEEEALRRKERL-KALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDED 81
           R +EE +R +E + +   EK G ++++  E + K   +EE    +  ++R +     +++
Sbjct: 629 REQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQE 688

Query: 82  LKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLK 141
            K R   +      E+  +++ +  + E  ++E +       +  W+ +  + ++ EK++
Sbjct: 689 EKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 748

Query: 142 K 142
           +
Sbjct: 749 E 749


>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 245

 Score = 46.6 bits (109), Expect = 1e-05
 Identities = 40/141 (28%), Positives = 63/141 (44%), Gaps = 13/141 (9%)

Query: 26  EEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKKR 85
           +E   +++R K  +++ GR  KE  E + K  R+ EE  E+ R+   R    E ++ KKR
Sbjct: 107 KEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKR 166

Query: 86  RVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLK-----RDVAKKLEKL 140
              Q      E K KE+ E  K E         N   RK + + K     +   KK E+ 
Sbjct: 167 ERKQVGEKEEERKEKERKERKKRE--------RNRKERKKERERKERRERKKERKKKEER 218

Query: 141 KKRTQRAIAELIRERLKGQED 161
           KK  Q+      RE+ +G+ +
Sbjct: 219 KKERQKDRQTNWREKERGKRE 239



 Score = 44.3 bits (103), Expect = 6e-05
 Identities = 39/145 (26%), Positives = 70/145 (48%), Gaps = 14/145 (9%)

Query: 15  EATTAGVGRLEEEALRRKERL---KALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELR 71
           E  T   G+ E E+ R+KER    K  RE+   + +E G+ + K  R++EE   K R   
Sbjct: 44  EIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRRE 103

Query: 72  LRNYVPEDEDLKKRRVPQAK-PVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLK 130
             N   E+++ +K++  + +   + E K +E+ E  K E   E         RK +   +
Sbjct: 104 KENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKER-------ERKKE---E 153

Query: 131 RDVAKKLEKLKKRTQRAIAELIRER 155
           R+  ++ ++ KKR ++ + E   ER
Sbjct: 154 REKERERKERKKRERKQVGEKEEER 178



 Score = 37.7 bits (86), Expect = 0.005
 Identities = 31/130 (23%), Positives = 55/130 (42%), Gaps = 5/130 (3%)

Query: 13  KMEATTAGVGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRL 72
           K    T+  G+  E    RK   +  RE+   + +++ E K +  RE ++ GEK  E + 
Sbjct: 121 KERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERK- 179

Query: 73  RNYVPEDEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRD 132
                ++   +K+R    K    E + KE+ E  K     EE        R+ +W  K  
Sbjct: 180 ----EKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKER 235

Query: 133 VAKKLEKLKK 142
             ++ ++ KK
Sbjct: 236 GKRERKERKK 245



 Score = 33.9 bits (76), Expect = 0.077
 Identities = 32/137 (23%), Positives = 64/137 (46%), Gaps = 2/137 (1%)

Query: 25  EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKK 84
           E E   RKE  K  RE   +K++ + E K K  RE+E + E+ ++ +      E+ + KK
Sbjct: 42  EREIETRKEGKKE-RESERKKERRERE-KRKREREKERKRERGKKEKKGERKKEERERKK 99

Query: 85  RRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKKRT 144
           RR  +      E++ +++ E  +     +E         +   + K    KK E+ K+R 
Sbjct: 100 RRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERE 159

Query: 145 QRAIAELIRERLKGQED 161
           ++   +  R+++  +E+
Sbjct: 160 RKERKKRERKQVGEKEE 176


>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 123

 Score = 43.9 bits (102), Expect = 7e-05
 Identities = 23/67 (34%), Positives = 41/67 (61%), Gaps = 1/67 (1%)

Query: 25  EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKK 84
           EEE  +RK + K  +E+  R+++E+ E + K   EE+EEG + ++ + R    E+E+ KK
Sbjct: 56  EEEEKKRKRKRKKKKEEEEREEEEEEEEEEKE-EEEKEEGRRRKKKKKRRRKEEEEEKKK 114

Query: 85  RRVPQAK 91
           +R  + K
Sbjct: 115 KRRRKTK 121



 Score = 40.4 bits (93), Expect = 8e-04
 Identities = 31/122 (25%), Positives = 57/122 (46%), Gaps = 8/122 (6%)

Query: 25  EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKK 84
           E E     E  +   EK G++     + K K  R+E+E+ +K +E   R    E+E  +K
Sbjct: 9   ETEETEETEETEEEEEKEGKR-----KEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRK 63

Query: 85  RRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKKRT 144
           R+  + K     E+ +E+ E  K E   EE +      +K     K +  +K +K +++T
Sbjct: 64  RKRKKKKEEEEREEEEEEEEEEKEE---EEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120

Query: 145 QR 146
           ++
Sbjct: 121 KK 122



 Score = 35.0 bits (79), Expect = 0.034
 Identities = 27/116 (23%), Positives = 52/116 (44%)

Query: 40  EKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKKRRVPQAKPVAVEEKV 99
           +K  +K KE  E +     EEEEE E  R+ + +    E E  KK +  + +    EE+ 
Sbjct: 1   KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60

Query: 100 KEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKKRTQRAIAELIRER 155
           K + +  K +   E  +       + + + K +  ++ +K K+R +    E  ++R
Sbjct: 61  KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKR 116



 Score = 34.7 bits (78), Expect = 0.045
 Identities = 26/119 (21%), Positives = 54/119 (45%), Gaps = 1/119 (0%)

Query: 39  REKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKKRRVPQAKPVAVEEK 98
           ++K  +K+ E+ E +T+   EEEE+  K +E R      +++  K +   + K    EEK
Sbjct: 2   KKKKKKKETEETE-ETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60

Query: 99  VKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKKRTQRAIAELIRERLK 157
            +++    K E    E +       K + + +    +K +K ++R +    +  + R K
Sbjct: 61  KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRK 119


>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
           [Homo sapiens]
          Length = 918

 Score = 43.9 bits (102), Expect = 7e-05
 Identities = 37/153 (24%), Positives = 74/153 (48%), Gaps = 12/153 (7%)

Query: 23  RLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDL 82
           RL EE  ++K   K + E   R+ +E+   + + L++EEEE  +H+EL  +    E E L
Sbjct: 617 RLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEE-RRHQELLQKKKEEEQERL 675

Query: 83  KK---------RRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDL--KR 131
           +K         +R  + +     E+ + + E  + E   +E  LA    R+    L  +R
Sbjct: 676 RKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAER 735

Query: 132 DVAKKLEKLKKRTQRAIAELIRERLKGQEDSLA 164
           ++ ++ + L+ + ++   EL  ++ K ++  LA
Sbjct: 736 ELQEREKALRLQKEQLQRELEEKKKKEEQQRLA 768



 Score = 41.2 bits (95), Expect = 5e-04
 Identities = 39/148 (26%), Positives = 73/148 (49%), Gaps = 14/148 (9%)

Query: 27  EALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKKRR 86
           E LRRKE  + LR +   +DK     + K  REE       + L+ R  V + ++ KK++
Sbjct: 543 ENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREE----RLRKVLQARERVEQMKEEKKKQ 598

Query: 87  VPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRK-PDWDLKRDVAKKLEKLK---- 141
           + Q K   ++EK     E AK E + EE      A +K  + + +R   ++  +L+    
Sbjct: 599 IEQ-KFAQIDEKT----EKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQ 653

Query: 142 KRTQRAIAELIRERLKGQEDSLASAVDA 169
           +  +R   EL++++ + +++ L  A +A
Sbjct: 654 EEEERRHQELLQKKKEEEQERLRKAAEA 681



 Score = 35.0 bits (79), Expect = 0.034
 Identities = 42/170 (24%), Positives = 77/170 (45%), Gaps = 27/170 (15%)

Query: 19  AGVGRLEEEALRRKERLKALR-------------EKTGRKDKEDGEPKTKHLRE-----E 60
           A   ++EE   RRK+  +A R             ++  +K KE+ + + +   E     E
Sbjct: 627 AAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAE 686

Query: 61  EEEGEKHRELRLRNYVPEDEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANL 120
           + E E+  + R      E E  ++ R  Q + +A +E+ +EQ E  + E  ++E + A  
Sbjct: 687 QREQERREQERREQERREQERREQERREQERQLAEQERRREQ-ERLQAERELQEREKALR 745

Query: 121 APRKPDWDLKRDVAKKLEKLKKRTQRAIAELIRERLKGQEDSLASAVDAA 170
             ++    L+R++    EK KK  Q+ +AE  R+  + QE     A  A+
Sbjct: 746 LQKE---QLQRELE---EKKKKEEQQRLAE--RQLQEEQEKKAKEAAGAS 787



 Score = 31.2 bits (69), Expect = 0.50
 Identities = 37/172 (21%), Positives = 74/172 (43%), Gaps = 36/172 (20%)

Query: 23  RLEEEALRRKERL------------------KALREKTGRKDKEDGEPKTKHLREE---- 60
           RLEE  L+R+ERL                  K + +K  + D++  + K + L EE    
Sbjct: 566 RLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKK 625

Query: 61  --------EEEGEKHRE---LRLRNYVPEDEDLKKRRVPQAKPVAVEEKVKEQLEAAKPE 109
                   E E  + +E    RLR    E+E+ + + + Q K    +E++++  EA +  
Sbjct: 626 KAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKR-- 683

Query: 110 PVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKKRTQRAIAELIRERLKGQED 161
            + E+ +       + + + +    ++ E+ ++  Q A  E  RE+ + Q +
Sbjct: 684 -LAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAE 734



 Score = 30.0 bits (66), Expect = 1.1
 Identities = 26/81 (32%), Positives = 38/81 (46%), Gaps = 1/81 (1%)

Query: 25  EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKK 84
           E+E  R +ERL+A RE   R +K     K +  RE EE+ +K  + RL     ++E  KK
Sbjct: 721 EQERRREQERLQAERELQER-EKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKK 779

Query: 85  RRVPQAKPVAVEEKVKEQLEA 105
            +       A+   V  Q  A
Sbjct: 780 AKEAAGASKALNVTVDVQSPA 800


>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
           [Homo sapiens]
          Length = 914

 Score = 43.9 bits (102), Expect = 7e-05
 Identities = 37/153 (24%), Positives = 74/153 (48%), Gaps = 12/153 (7%)

Query: 23  RLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDL 82
           RL EE  ++K   K + E   R+ +E+   + + L++EEEE  +H+EL  +    E E L
Sbjct: 613 RLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEE-RRHQELLQKKKEEEQERL 671

Query: 83  KK---------RRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDL--KR 131
           +K         +R  + +     E+ + + E  + E   +E  LA    R+    L  +R
Sbjct: 672 RKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAER 731

Query: 132 DVAKKLEKLKKRTQRAIAELIRERLKGQEDSLA 164
           ++ ++ + L+ + ++   EL  ++ K ++  LA
Sbjct: 732 ELQEREKALRLQKEQLQRELEEKKKKEEQQRLA 764



 Score = 41.2 bits (95), Expect = 5e-04
 Identities = 39/148 (26%), Positives = 73/148 (49%), Gaps = 14/148 (9%)

Query: 27  EALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKKRR 86
           E LRRKE  + LR +   +DK     + K  REE       + L+ R  V + ++ KK++
Sbjct: 539 ENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREE----RLRKVLQARERVEQMKEEKKKQ 594

Query: 87  VPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRK-PDWDLKRDVAKKLEKLK---- 141
           + Q K   ++EK     E AK E + EE      A +K  + + +R   ++  +L+    
Sbjct: 595 IEQ-KFAQIDEKT----EKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQ 649

Query: 142 KRTQRAIAELIRERLKGQEDSLASAVDA 169
           +  +R   EL++++ + +++ L  A +A
Sbjct: 650 EEEERRHQELLQKKKEEEQERLRKAAEA 677



 Score = 35.0 bits (79), Expect = 0.034
 Identities = 42/170 (24%), Positives = 77/170 (45%), Gaps = 27/170 (15%)

Query: 19  AGVGRLEEEALRRKERLKALR-------------EKTGRKDKEDGEPKTKHLRE-----E 60
           A   ++EE   RRK+  +A R             ++  +K KE+ + + +   E     E
Sbjct: 623 AAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAE 682

Query: 61  EEEGEKHRELRLRNYVPEDEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANL 120
           + E E+  + R      E E  ++ R  Q + +A +E+ +EQ E  + E  ++E + A  
Sbjct: 683 QREQERREQERREQERREQERREQERREQERQLAEQERRREQ-ERLQAERELQEREKALR 741

Query: 121 APRKPDWDLKRDVAKKLEKLKKRTQRAIAELIRERLKGQEDSLASAVDAA 170
             ++    L+R++    EK KK  Q+ +AE  R+  + QE     A  A+
Sbjct: 742 LQKE---QLQRELE---EKKKKEEQQRLAE--RQLQEEQEKKAKEAAGAS 783



 Score = 31.2 bits (69), Expect = 0.50
 Identities = 37/172 (21%), Positives = 74/172 (43%), Gaps = 36/172 (20%)

Query: 23  RLEEEALRRKERL------------------KALREKTGRKDKEDGEPKTKHLREE---- 60
           RLEE  L+R+ERL                  K + +K  + D++  + K + L EE    
Sbjct: 562 RLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKK 621

Query: 61  --------EEEGEKHRE---LRLRNYVPEDEDLKKRRVPQAKPVAVEEKVKEQLEAAKPE 109
                   E E  + +E    RLR    E+E+ + + + Q K    +E++++  EA +  
Sbjct: 622 KAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKR-- 679

Query: 110 PVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKKRTQRAIAELIRERLKGQED 161
            + E+ +       + + + +    ++ E+ ++  Q A  E  RE+ + Q +
Sbjct: 680 -LAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAE 730



 Score = 30.0 bits (66), Expect = 1.1
 Identities = 26/81 (32%), Positives = 38/81 (46%), Gaps = 1/81 (1%)

Query: 25  EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKK 84
           E+E  R +ERL+A RE   R +K     K +  RE EE+ +K  + RL     ++E  KK
Sbjct: 717 EQERRREQERLQAERELQER-EKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKK 775

Query: 85  RRVPQAKPVAVEEKVKEQLEA 105
            +       A+   V  Q  A
Sbjct: 776 AKEAAGASKALNVTVDVQSPA 796


>gi|12711674 UPF3 regulator of nonsense transcripts homolog B
           isoform 2 [Homo sapiens]
          Length = 470

 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 39/153 (25%), Positives = 73/153 (47%), Gaps = 20/153 (13%)

Query: 25  EEEALRRK--ERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDL 82
           EEE  +RK  E+LK + ++   +DK   EPK K L++ E+  EK  + R +    + E+L
Sbjct: 238 EEEKRKRKDIEKLKKI-DRIPERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKLDKENL 296

Query: 83  KKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKK 142
              R    +   + ++   +L+  K              P++P+ +  RD  ++  + ++
Sbjct: 297 SDERA-SGQSCTLPKRSDSELKDEK--------------PKRPEDESGRDYREREREYER 341

Query: 143 RTQRAIAELIRERLKGQEDSLASAVDAATEQKT 175
             +R + E  RERLK QE+      +   ++KT
Sbjct: 342 DQERILRE--RERLKRQEEERRRQKERYEKEKT 372



 Score = 32.0 bits (71), Expect = 0.29
 Identities = 23/89 (25%), Positives = 46/89 (51%), Gaps = 11/89 (12%)

Query: 23  RLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDL 82
           R +E  LR +ERLK  R++  R+ +++   K K  + +EEE +K ++  LR+        
Sbjct: 341 RDQERILRERERLK--RQEEERRRQKERYEKEKTFKRKEEEMKKEKD-TLRD-------- 389

Query: 83  KKRRVPQAKPVAVEEKVKEQLEAAKPEPV 111
           K ++    + +   EK +++ E  K + +
Sbjct: 390 KGKKAESTESIGSSEKTEKKEEVVKRDRI 418


>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
           sapiens]
          Length = 1293

 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 35/138 (25%), Positives = 68/138 (49%), Gaps = 9/138 (6%)

Query: 23  RLEEEALRR-KERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDED 81
           R +EEALRR +E+  ALR +   ++++  E   + L E   E E+ R+        ++E 
Sbjct: 782 RKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRK--------QEEL 833

Query: 82  LKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLK 141
           L+K+    AK    EE+ + +LE  +     E   L +    +   +L+    K+L + +
Sbjct: 834 LRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQR 893

Query: 142 KRTQRAIAELIRERLKGQ 159
           ++ Q A+  L +++ + Q
Sbjct: 894 QQQQEALRRLQQQQQQQQ 911



 Score = 39.3 bits (90), Expect = 0.002
 Identities = 37/155 (23%), Positives = 75/155 (48%), Gaps = 18/155 (11%)

Query: 7   GGAYAGKMEATTAGVGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHL--REEEEEG 64
           G A     +   A   +LE+E  RR+  ++A RE+  RK +E+   + + +  R++EEE 
Sbjct: 714 GPALEQLQQLEKAKAAKLEQE--RREAEMRAKREEEERKRQEELRRQQEEILRRQQEEER 771

Query: 65  EKHRELRLRNYVPEDEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRK 124
           ++           E+E+L +R+  +A     E+++  + +  + E   +E  L  L  R+
Sbjct: 772 KRR----------EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERR 821

Query: 125 PDWDLKRDVAKKLEKLKKRTQRAIAELIRERLKGQ 159
            + + +R    K E+L ++ +   A+  RE  + Q
Sbjct: 822 REEEERR----KQEELLRKQEEEAAKWAREEEEAQ 852


>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
           sapiens]
          Length = 1320

 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 35/138 (25%), Positives = 68/138 (49%), Gaps = 9/138 (6%)

Query: 23  RLEEEALRR-KERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDED 81
           R +EEALRR +E+  ALR +   ++++  E   + L E   E E+ R+        ++E 
Sbjct: 809 RKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRK--------QEEL 860

Query: 82  LKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLK 141
           L+K+    AK    EE+ + +LE  +     E   L +    +   +L+    K+L + +
Sbjct: 861 LRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQR 920

Query: 142 KRTQRAIAELIRERLKGQ 159
           ++ Q A+  L +++ + Q
Sbjct: 921 QQQQEALRRLQQQQQQQQ 938



 Score = 39.3 bits (90), Expect = 0.002
 Identities = 37/155 (23%), Positives = 75/155 (48%), Gaps = 18/155 (11%)

Query: 7   GGAYAGKMEATTAGVGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHL--REEEEEG 64
           G A     +   A   +LE+E  RR+  ++A RE+  RK +E+   + + +  R++EEE 
Sbjct: 741 GPALEQLQQLEKAKAAKLEQE--RREAEMRAKREEEERKRQEELRRQQEEILRRQQEEER 798

Query: 65  EKHRELRLRNYVPEDEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRK 124
           ++           E+E+L +R+  +A     E+++  + +  + E   +E  L  L  R+
Sbjct: 799 KRR----------EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERR 848

Query: 125 PDWDLKRDVAKKLEKLKKRTQRAIAELIRERLKGQ 159
            + + +R    K E+L ++ +   A+  RE  + Q
Sbjct: 849 REEEERR----KQEELLRKQEEEAAKWAREEEEAQ 879


>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
           sapiens]
          Length = 1299

 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 35/138 (25%), Positives = 68/138 (49%), Gaps = 9/138 (6%)

Query: 23  RLEEEALRR-KERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDED 81
           R +EEALRR +E+  ALR +   ++++  E   + L E   E E+ R+        ++E 
Sbjct: 788 RKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRK--------QEEL 839

Query: 82  LKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLK 141
           L+K+    AK    EE+ + +LE  +     E   L +    +   +L+    K+L + +
Sbjct: 840 LRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQR 899

Query: 142 KRTQRAIAELIRERLKGQ 159
           ++ Q A+  L +++ + Q
Sbjct: 900 QQQQEALRRLQQQQQQQQ 917



 Score = 39.3 bits (90), Expect = 0.002
 Identities = 37/155 (23%), Positives = 75/155 (48%), Gaps = 18/155 (11%)

Query: 7   GGAYAGKMEATTAGVGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHL--REEEEEG 64
           G A     +   A   +LE+E  RR+  ++A RE+  RK +E+   + + +  R++EEE 
Sbjct: 720 GPALEQLQQLEKAKAAKLEQE--RREAEMRAKREEEERKRQEELRRQQEEILRRQQEEER 777

Query: 65  EKHRELRLRNYVPEDEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRK 124
           ++           E+E+L +R+  +A     E+++  + +  + E   +E  L  L  R+
Sbjct: 778 KRR----------EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERR 827

Query: 125 PDWDLKRDVAKKLEKLKKRTQRAIAELIRERLKGQ 159
            + + +R    K E+L ++ +   A+  RE  + Q
Sbjct: 828 REEEERR----KQEELLRKQEEEAAKWAREEEEAQ 858


>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
           sapiens]
          Length = 1299

 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 35/138 (25%), Positives = 68/138 (49%), Gaps = 9/138 (6%)

Query: 23  RLEEEALRR-KERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDED 81
           R +EEALRR +E+  ALR +   ++++  E   + L E   E E+ R+        ++E 
Sbjct: 788 RKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRK--------QEEL 839

Query: 82  LKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLK 141
           L+K+    AK    EE+ + +LE  +     E   L +    +   +L+    K+L + +
Sbjct: 840 LRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQR 899

Query: 142 KRTQRAIAELIRERLKGQ 159
           ++ Q A+  L +++ + Q
Sbjct: 900 QQQQEALRRLQQQQQQQQ 917



 Score = 39.3 bits (90), Expect = 0.002
 Identities = 37/155 (23%), Positives = 75/155 (48%), Gaps = 18/155 (11%)

Query: 7   GGAYAGKMEATTAGVGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHL--REEEEEG 64
           G A     +   A   +LE+E  RR+  ++A RE+  RK +E+   + + +  R++EEE 
Sbjct: 720 GPALEQLQQLEKAKAAKLEQE--RREAEMRAKREEEERKRQEELRRQQEEILRRQQEEER 777

Query: 65  EKHRELRLRNYVPEDEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRK 124
           ++           E+E+L +R+  +A     E+++  + +  + E   +E  L  L  R+
Sbjct: 778 KRR----------EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERR 827

Query: 125 PDWDLKRDVAKKLEKLKKRTQRAIAELIRERLKGQ 159
            + + +R    K E+L ++ +   A+  RE  + Q
Sbjct: 828 REEEERR----KQEELLRKQEEEAAKWAREEEEAQ 858


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 34/122 (27%), Positives = 58/122 (47%), Gaps = 4/122 (3%)

Query: 25   EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKK 84
            EEE L R+ER K  R++  R+ +E+ E + +  +   EE EK R   L     E+E+L++
Sbjct: 1119 EEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQ 1178

Query: 85   RRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKKRT 144
                + + +  EE+ K + E  +     EE+       R  D D + D+  + E  K+  
Sbjct: 1179 ----EEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENA 1234

Query: 145  QR 146
             R
Sbjct: 1235 VR 1236



 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 39/138 (28%), Positives = 68/138 (49%), Gaps = 21/138 (15%)

Query: 25   EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKK 84
            EE+ LRR+ER +  RE+  R      EP+ K L   EEE + HR+ R R ++ E++ L++
Sbjct: 1490 EEQQLRRQERDRKFREQELRSQ----EPERKFL---EEEQQLHRQQRQRKFLQEEQQLRR 1542

Query: 85   RRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKKRT 144
            +   Q +    + K +E+ +  +     EE  L+           +RD   +LE+ K R 
Sbjct: 1543 QERGQQRRQDRDRKFREEEQLRQER---EEQQLSR---------QERDRKFRLEEQKVRR 1590

Query: 145  QRAIAELI--RERLKGQE 160
            Q    + +   ++L+ QE
Sbjct: 1591 QEQERKFMEDEQQLRRQE 1608



 Score = 42.4 bits (98), Expect = 2e-04
 Identities = 35/152 (23%), Positives = 70/152 (46%), Gaps = 1/152 (0%)

Query: 23  RLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDL 82
           R EE+  R + R + L E+ G++ ++  + + + L E EE+ EK   L  R+    DE+L
Sbjct: 114 RQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEEL 173

Query: 83  KKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKK 142
            ++R  + +        +EQL++ K     E  D   L  R+     ++   +K ++ ++
Sbjct: 174 WRQR-QEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRE 232

Query: 143 RTQRAIAELIRERLKGQEDSLASAVDAATEQK 174
           R  R   E   +  + +E  L    +   E++
Sbjct: 233 RQDRVFQEEEEKEWRKRETVLRKEEEKLQEEE 264



 Score = 42.4 bits (98), Expect = 2e-04
 Identities = 35/136 (25%), Positives = 72/136 (52%), Gaps = 15/136 (11%)

Query: 25   EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKK 84
            +E+ LRR+E  + LR++  RK +ED     + L +E EE + HR+ R R ++ E+  L++
Sbjct: 1600 DEQQLRRQEGQQQLRQERDRKFRED-----EQLLQEREEQQLHRQERDRKFLEEEPQLRR 1654

Query: 85   RRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKKRT 144
            +   Q      + K +E+      E +++E +   L  R+ + D K    ++  + ++R 
Sbjct: 1655 QEREQQLRHDRDRKFREE------EQLLQEGEEQQL--RRQERDRKFREEEQQLRRQERE 1706

Query: 145  QRAIAELIRERLKGQE 160
            ++ + E   ++L+ QE
Sbjct: 1707 RKFLQE--EQQLRRQE 1720



 Score = 42.0 bits (97), Expect = 3e-04
 Identities = 37/152 (24%), Positives = 69/152 (45%), Gaps = 3/152 (1%)

Query: 25  EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKK 84
           EEE LR+ ER +  RE+   + ++    + + LR ++EE  + ++   R      E  ++
Sbjct: 274 EEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEE 333

Query: 85  RRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKKRT 144
           RR  Q +    EE+ ++QL   + E   E+         + +  L+R+   + E+  +R 
Sbjct: 334 RREQQLRR-EQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRRE 392

Query: 145 Q--RAIAELIRERLKGQEDSLASAVDAATEQK 174
           Q  R   +L RE+   +E  L        EQ+
Sbjct: 393 QQLRREQQLRREQQLRREQQLRREQQLRREQQ 424



 Score = 41.6 bits (96), Expect = 4e-04
 Identities = 34/139 (24%), Positives = 74/139 (53%), Gaps = 16/139 (11%)

Query: 26  EEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKK- 84
           E+ LRR+++L+  RE+  R+++E+   + KH +E  E+  K  +   R+++  +E+ ++ 
Sbjct: 410 EQQLRREQQLR--REQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERH 467

Query: 85  ---RRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLK 141
              RR  Q K    EE+ +  L+       +EE +      R+ +  L+R+  ++ E+  
Sbjct: 468 EQERRKQQLKRDQEEERRERWLK-------LEEEERREQQERR-EQQLRREQEERREQRL 519

Query: 142 KRTQRAIAELIRERLKGQE 160
           KR +    E +++RL+ ++
Sbjct: 520 KRQEE--EERLQQRLRSEQ 536



 Score = 41.6 bits (96), Expect = 4e-04
 Identities = 42/147 (28%), Positives = 73/147 (49%), Gaps = 21/147 (14%)

Query: 27  EALRRKERLKALREKTGRKD---------KEDGEPKTKHLREEEEEGEKHRELRLRNYVP 77
           E  RRK++LK  +E+  R+          +E  E + + LR E+EE    RE RL+    
Sbjct: 468 EQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEE---RREQRLKRQ-E 523

Query: 78  EDEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIE----EVDLANLAPRKPDWDLKRDV 133
           E+E L++R   + +    +E+ +EQL   + E  +E    E  L      + D  LKR+ 
Sbjct: 524 EEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREE 583

Query: 134 AKKLEKLKKRTQRAIAELIRERLKGQE 160
            ++ ++LK+  +    E + +RLK +E
Sbjct: 584 ERRQQRLKREQE----ERLEQRLKREE 606



 Score = 40.8 bits (94), Expect = 6e-04
 Identities = 39/169 (23%), Positives = 78/169 (46%), Gaps = 19/169 (11%)

Query: 25   EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKK 84
            EEE L R+E  K  R++  R+ +E+ E + +  +   EE EK R+ R R Y  E+E  ++
Sbjct: 1149 EEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQ 1208

Query: 85   RRVPQAKPVAVEEKVKEQLEAAKPEPV--------------IEEVDLANLAPRKPDWDLK 130
            +R  + +       +K Q E  K   V                +++ + L  R+   DL+
Sbjct: 1209 KRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQ 1268

Query: 131  RDVAKKLEKLKKRTQRAIAELIR-----ERLKGQEDSLASAVDAATEQK 174
              + ++ E+ +++ +R   +  R     E+L+ +E   A   D  ++++
Sbjct: 1269 HLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEE 1317



 Score = 39.7 bits (91), Expect = 0.001
 Identities = 28/136 (20%), Positives = 74/136 (54%), Gaps = 7/136 (5%)

Query: 27  EALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKKRR 86
           E   R+E+ +  RE+  R+++E  E + + LR E+EE  + ++LR      ++E+ ++++
Sbjct: 323 EQQERREQQEERREQQLRREQE--ERREQQLRREQEEERREQQLRRE----QEEERREQQ 376

Query: 87  VPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKKR-TQ 145
           + + + +  E++++ + +  + + +  E  L      + +  L+R+   + E+ ++R  Q
Sbjct: 377 LRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQ 436

Query: 146 RAIAELIRERLKGQED 161
           +   E   +RLK +++
Sbjct: 437 KHEQERREQRLKREQE 452



 Score = 39.3 bits (90), Expect = 0.002
 Identities = 33/145 (22%), Positives = 71/145 (48%), Gaps = 10/145 (6%)

Query: 25  EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKK 84
           +EE  R ++RL++  E+  R+++E+   +     EE+   ++ RE RL+    E  D   
Sbjct: 522 QEEEERLQQRLRS--EQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLL 579

Query: 85  RRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDL-----ANLAPRKPDWDLKRDVAKKLEK 139
           +R  + +   ++ + +E+LE       +E ++        L   +P+ + ++ + K  E+
Sbjct: 580 KREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQ 639

Query: 140 LKKRTQ---RAIAELIRERLKGQED 161
            ++R Q   R   E   +RLK +E+
Sbjct: 640 EERRQQQLRREQQERREQRLKREEE 664



 Score = 39.3 bits (90), Expect = 0.002
 Identities = 36/150 (24%), Positives = 75/150 (50%), Gaps = 19/150 (12%)

Query: 25   EEEALRRKERLKALREKTGRKDKED----GEPKTKHLREE-------EEEGEKHRELRLR 73
            EE  LRR+ER + LR    RK +E+     E + + LR +       EEE +  R+ R R
Sbjct: 1648 EEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERER 1707

Query: 74   NYVPEDEDLKKRRVPQAKPVAVEEKVK---EQLEAAKPEPVIEEVDLANLAPRKPDWDLK 130
             ++ E++ L+++ +   +    EE+++   EQ +  + E   + ++   L P + +  L+
Sbjct: 1708 KFLQEEQQLRRQEL--ERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLR 1765

Query: 131  RDVAKKLEKLKKRTQRAIAELIRERLKGQE 160
            R   ++ ++  +  ++   E   ++L+ QE
Sbjct: 1766 R---QERDRKFREEEQLRQEREEQQLRSQE 1792



 Score = 38.9 bits (89), Expect = 0.002
 Identities = 33/139 (23%), Positives = 69/139 (49%), Gaps = 9/139 (6%)

Query: 25  EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKK 84
           +++ LRR+++L+  +E+  R+ +E+     +  +E  E+ E+ RE +LR    E  + + 
Sbjct: 296 QQQRLRREQQLRRKQEEERREQQEE----RREQQERREQQEERREQQLRREQEERREQQL 351

Query: 85  RRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKKRT 144
           RR  Q +    ++  +EQ E  + + +  E  L      + +  L+R+   + E+  +R 
Sbjct: 352 RR-EQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 410

Query: 145 QRAIAELIRERLKGQEDSL 163
           Q    +L RE+   +E  L
Sbjct: 411 Q----QLRREQQLRREQQL 425



 Score = 38.9 bits (89), Expect = 0.002
 Identities = 36/147 (24%), Positives = 72/147 (48%), Gaps = 11/147 (7%)

Query: 25   EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDL-- 82
            EEE L R+ER K  R++  R+ ++D + + K  +   EE EK R         E+E+L  
Sbjct: 939  EEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQ 998

Query: 83   -------KKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAK 135
                   ++R   + +    + + K++L+  + + + EE +   L  R+  +  + ++ +
Sbjct: 999  EEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQ 1058

Query: 136  KLEKL--KKRTQRAIAELIRERLKGQE 160
            + E+L  ++R  R   EL R+  K +E
Sbjct: 1059 EEEQLLGEERETRRRQELERQYRKEEE 1085



 Score = 38.1 bits (87), Expect = 0.004
 Identities = 40/150 (26%), Positives = 68/150 (45%), Gaps = 11/150 (7%)

Query: 26  EEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEE----EGEKHRELRLRNYVPEDED 81
           E+  RR + LK   E+  ++ K + E + +   + EE    E E+ RE RL+   PE+E 
Sbjct: 570 EQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEE- 628

Query: 82  LKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKR--DVAKKLEK 139
              RR    K    EE+ ++QL   + E   + +       R  +  LKR  +  ++ ++
Sbjct: 629 ---RRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERL-EQRLKREHEEERREQE 684

Query: 140 LKKRTQRAIAELIRERLKGQEDSLASAVDA 169
           L +  Q    E I+ R+   +  L S  DA
Sbjct: 685 LAEEEQEQARERIKSRIPKWQWQLESEADA 714



 Score = 38.1 bits (87), Expect = 0.004
 Identities = 21/65 (32%), Positives = 39/65 (60%), Gaps = 3/65 (4%)

Query: 25   EEEALRRKERLKALREKTGRKDKEDGEPKTKHLRE---EEEEGEKHRELRLRNYVPEDED 81
            EE+ LR +ER + LR+   RK +E+ +  ++  R+    EEE +  R+ R R ++ E++ 
Sbjct: 1395 EEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQ 1454

Query: 82   LKKRR 86
            L++ R
Sbjct: 1455 LRQER 1459



 Score = 37.7 bits (86), Expect = 0.005
 Identities = 31/150 (20%), Positives = 74/150 (49%), Gaps = 22/150 (14%)

Query: 23  RLEEEALRRKERLKA----LREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPE 78
           R E++  RR+++L+      RE+  R+++E+ E + + LR E+EE  + ++LR    +  
Sbjct: 327 RREQQEERREQQLRREQEERREQQLRREQEE-ERREQQLRREQEEERREQQLRREQQLRR 385

Query: 79  DEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLE 138
           ++ L++           E++++ + +  + + +  E  L      + +  L+R+  ++  
Sbjct: 386 EQQLRR-----------EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERH 434

Query: 139 KLKKRTQRAIAELIRER------LKGQEDS 162
           + K   +R    L RE+      LK +E++
Sbjct: 435 EQKHEQERREQRLKREQEERRDWLKREEET 464



 Score = 37.7 bits (86), Expect = 0.005
 Identities = 37/150 (24%), Positives = 71/150 (47%), Gaps = 16/150 (10%)

Query: 25  EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKK 84
           EEE L+R+ER + L+E      +EDG  + +  R  +E+    R+ + R +  E+E  ++
Sbjct: 836 EEEQLQRRERAQQLQE------EEDGLQEDQERRRSQEQ---RRDQKWR-WQLEEERKRR 885

Query: 85  RRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKKRT 144
           R    AKP   E+  KEQ    + E  ++  +      ++ +   + +     E+L++  
Sbjct: 886 RHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREE-----EQLQQEE 940

Query: 145 QRAIAELIRERLKGQEDSLASAVDAATEQK 174
           ++ + E  RE+ + QE       D   +QK
Sbjct: 941 EQLLRE-EREKRRRQERERQYRKDKKLQQK 969



 Score = 37.4 bits (85), Expect = 0.007
 Identities = 40/151 (26%), Positives = 71/151 (47%), Gaps = 27/151 (17%)

Query: 25   EEEALRRKERLKALREKTGRKDKEDGEPKTKH---LREEEEEGEKHRELRLRNYVPE--- 78
            EEE L+R+ER K  R++  R+ +E+ + + +    LREE E  ++ R+ R R Y  +   
Sbjct: 909  EEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREERE--KRRRQERERQYRKDKKL 966

Query: 79   ---------DEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDL 129
                     +E  K+RR  + K    EE+++++ E    E   +         R+ +W+ 
Sbjct: 967  QQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKR--------RRQEWE- 1017

Query: 130  KRDVAKKLEKLKKRTQRAIAELIRERLKGQE 160
             R   KK E  ++  Q    E  + RL+ +E
Sbjct: 1018 -RQYRKKDELQQEEEQLLREEREKRRLQERE 1047



 Score = 37.0 bits (84), Expect = 0.009
 Identities = 35/133 (26%), Positives = 65/133 (48%), Gaps = 10/133 (7%)

Query: 25   EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKK 84
            EEE L R+E  K  R++  R+ +E+ E + +  +   EE EK R   L     E+E++++
Sbjct: 1089 EEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQ 1148

Query: 85   RRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKKRT 144
                Q      E++ +++LE    E   EE+       ++ +  L R+  +K  + ++R 
Sbjct: 1149 EE-EQLLREEPEKRRRQELERQYREE--EEL-------QQEEEQLLREEQEKRRQERERQ 1198

Query: 145  QRAIAELIRERLK 157
             R   EL R++ K
Sbjct: 1199 YREEEELQRQKRK 1211



 Score = 37.0 bits (84), Expect = 0.009
 Identities = 34/132 (25%), Positives = 67/132 (50%), Gaps = 22/132 (16%)

Query: 23   RLEEEALRRKERLKA-------LREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNY 75
            R EE+ +RR+ER +        LR++  RK +E+     + L +E EE + HR+ R R +
Sbjct: 1433 REEEQQVRRQERERKFLEEEQQLRQERHRKFREE-----EQLLQEREEQQLHRQERDRKF 1487

Query: 76   VPEDEDLKKRRVPQAKPVAVEEKVKEQ-LEAAKPE-PVIEEVDLANLAPRKPDWDLKRDV 133
            + E++ L+++          + K +EQ L + +PE   +EE    +   R+  +  +   
Sbjct: 1488 LEEEQQLRRQE--------RDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQ 1539

Query: 134  AKKLEKLKKRTQ 145
             ++ E+ ++R Q
Sbjct: 1540 LRRQERGQQRRQ 1551



 Score = 36.6 bits (83), Expect = 0.012
 Identities = 34/136 (25%), Positives = 68/136 (50%), Gaps = 15/136 (11%)

Query: 25  EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKK 84
           +EE LRR+E L+  R+  GR++K+  + + +  R  +EE EK  E R R  V   E+ K 
Sbjct: 206 DEEQLRRRELLELRRK--GREEKQQ-QRRERQDRVFQEEEEK--EWRKRETVLRKEEEKL 260

Query: 85  RRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKKRT 144
           +          EE+ + Q E  + E  + +++   L   + + + ++   ++ ++L+++ 
Sbjct: 261 Q----------EEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQ 310

Query: 145 QRAIAELIRERLKGQE 160
           +    E   ER + QE
Sbjct: 311 EEERREQQEERREQQE 326



 Score = 36.6 bits (83), Expect = 0.012
 Identities = 34/145 (23%), Positives = 68/145 (46%), Gaps = 10/145 (6%)

Query: 23  RLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHR---ELRLRNYVPED 79
           +LEEE   R+E+ +   ++  R+ +E  E + K   EEE   ++ R   +LR       +
Sbjct: 490 KLEEE--ERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERRE 547

Query: 80  EDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVD-----LANLAPRKPDWDLKRDVA 134
           + LK+    + +    E+++K + E  + + +  E +     L      + +  LKR+  
Sbjct: 548 QLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEV 607

Query: 135 KKLEKLKKRTQRAIAELIRERLKGQ 159
           ++LE+ ++R QR   E   E  + Q
Sbjct: 608 ERLEQEERREQRLKREEPEEERRQQ 632



 Score = 36.2 bits (82), Expect = 0.015
 Identities = 30/138 (21%), Positives = 67/138 (48%), Gaps = 3/138 (2%)

Query: 25  EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEK--HRELRLRNYVPEDEDL 82
           EEE    ++R   LR++  +  +E+ + + + L+EEEE+  K   +ELR      E +  
Sbjct: 240 EEEEKEWRKRETVLRKEEEKLQEEEPQ-RQRELQEEEEQLRKLERQELRRERQEEEQQQQ 298

Query: 83  KKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKK 142
           + RR  Q +    EE+ ++Q E  + +   E+ +       + + + +R+   + E+ ++
Sbjct: 299 RLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEE 358

Query: 143 RTQRAIAELIRERLKGQE 160
           R ++ +     E  + Q+
Sbjct: 359 RREQQLRREQEEERREQQ 376



 Score = 35.8 bits (81), Expect = 0.020
 Identities = 25/91 (27%), Positives = 49/91 (53%), Gaps = 9/91 (9%)

Query: 23   RLEEEALRRKERLKALREKTGRKDKEDGEPK---TKHLREEEEEGEKHRELRLRNYV--- 76
            R EE+ LRR+ER +   ++  +  +++ E K    + LR+E E+ +  R+ R R  +   
Sbjct: 1694 REEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEE 1753

Query: 77   ---PEDEDLKKRRVPQAKPVAVEEKVKEQLE 104
               PE E+ + RR  + +    EE+++++ E
Sbjct: 1754 QLRPEREEQQLRRQERDRKFREEEQLRQERE 1784



 Score = 33.5 bits (75), Expect = 0.100
 Identities = 44/173 (25%), Positives = 75/173 (43%), Gaps = 53/173 (30%)

Query: 23  RLEEEALRRKERLKALREKTGRKD---KEDGEPKTKHLREEEEEG--------------- 64
           RLE+E  RR++RLK  RE+  R+D   K + E + + L+ E+EE                
Sbjct: 557 RLEQE--RREQRLK--REQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQ 612

Query: 65  EKHRELRLRNYVPEDE---------------------DLKKRRVPQAKPVAVEEKVKEQL 103
           E+ RE RL+   PE+E                     + ++RR  + K    EE+++++L
Sbjct: 613 EERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRL 672

Query: 104 ------EAAKPEPVIEEVDLA--NLAPRKP--DWDLKRDVAKKLEKLKKRTQR 146
                 E  + E   EE + A   +  R P   W L+ +   +  K+  R ++
Sbjct: 673 KREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRK 725



 Score = 33.1 bits (74), Expect = 0.13
 Identities = 32/150 (21%), Positives = 75/150 (50%), Gaps = 15/150 (10%)

Query: 23  RLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDL 82
           R +EE    ++  +  RE+  ++++E+     K     EEE E+H + R +  +  D++ 
Sbjct: 427 REQEEERHEQKHEQERREQRLKREQEERRDWLK----REEETERHEQERRKQQLKRDQEE 482

Query: 83  KKR----RVPQAKPVAVEEKVKEQL----EAAKPEPVIEEVDLANLAPR-KPDWDLKRDV 133
           ++R    ++ + +    +E+ ++QL    E  + + +  + +   L  R + +  L+R+ 
Sbjct: 483 ERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQ 542

Query: 134 AKKLEKLKKRTQ--RAIAELIRERLKGQED 161
            ++ E+L KR +  R   E   +RLK +++
Sbjct: 543 EERREQLLKREEEKRLEQERREQRLKREQE 572



 Score = 31.6 bits (70), Expect = 0.38
 Identities = 35/151 (23%), Positives = 72/151 (47%), Gaps = 14/151 (9%)

Query: 25   EEEALRRKERLKAL---REKTGRKDKEDGEPKTKHLREEEE---EGEKHRELRLRNYVPE 78
            EEE L R+ER K     RE+  R+++E  + + + L EE E     E  R+ R    + +
Sbjct: 1029 EEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQ 1088

Query: 79   DEDLKKRRVPQAKPVAVEE---KVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAK 135
            +E+   R  P+ +     E   + +E+L+  + + + EE +       +  +  + +V +
Sbjct: 1089 EEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQ 1148

Query: 136  KLEKL-----KKRTQRAIAELIRERLKGQED 161
            + E+L     +KR ++ +    RE  + Q++
Sbjct: 1149 EEEQLLREEPEKRRRQELERQYREEEELQQE 1179



 Score = 30.8 bits (68), Expect = 0.65
 Identities = 27/77 (35%), Positives = 39/77 (50%), Gaps = 16/77 (20%)

Query: 25   EEEALRRKERLKALRE------KTGRKDKED------GEPKTKHLREEEEEGEKHRELRL 72
            EE+ LRR+ER +  RE      + GRK  E+       E + K L+EE++   + RE +L
Sbjct: 1349 EEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQL 1408

Query: 73   RNYVPEDEDLKKRRVPQ 89
            R    +D D K R   Q
Sbjct: 1409 R----QDRDRKFREEEQ 1421



 Score = 29.6 bits (65), Expect = 1.4
 Identities = 11/45 (24%), Positives = 29/45 (64%)

Query: 26   EEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHREL 70
            +E  RR+E+     E+  R+ + + + + +H+R +++E ++HR++
Sbjct: 1854 QEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQV 1898



 Score = 29.3 bits (64), Expect = 1.9
 Identities = 31/131 (23%), Positives = 62/131 (47%), Gaps = 22/131 (16%)

Query: 25  EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKK 84
           EE++ R ++RL A              P  +  RE +   E+ R+ R + ++PE+E+ ++
Sbjct: 774 EEKSERGRQRLSA-------------RPPLREQRERQLRAEE-RQQREQRFLPEEEEKEQ 819

Query: 85  RRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKKRT 144
           RR  +       E+ KE L+  + E  ++  + A     + D  L+ D  ++  + ++R 
Sbjct: 820 RRRQR------REREKE-LQFLEEEEQLQRRERAQQLQEEED-GLQEDQERRRSQEQRRD 871

Query: 145 QRAIAELIRER 155
           Q+   +L  ER
Sbjct: 872 QKWRWQLEEER 882



 Score = 28.9 bits (63), Expect = 2.5
 Identities = 30/143 (20%), Positives = 60/143 (41%), Gaps = 12/143 (8%)

Query: 30   RRKERLKALREKT--GRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKK--- 84
            R  E+ + L +     R+ ++D +      +E + E E+ R  +   + PE+E L++   
Sbjct: 1245 RENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQ 1304

Query: 85   -------RRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKL 137
                   R+  + K +  EE+ +++          EE  L      +P    +RD   + 
Sbjct: 1305 KEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFRE 1364

Query: 138  EKLKKRTQRAIAELIRERLKGQE 160
            E+L+ + Q        +RL+ QE
Sbjct: 1365 EELRHQEQGRKFLEEEQRLRRQE 1387



 Score = 27.7 bits (60), Expect = 5.5
 Identities = 26/84 (30%), Positives = 42/84 (50%), Gaps = 12/84 (14%)

Query: 20   GVGRLEEEALRRKERLKALREKTGR--KDKEDGEPKTKHLREE----EEEGEKHRELRLR 73
            G  R EEE L+ +E+ + LR++  R  + +E    + K  REE    +EE +K R+ R R
Sbjct: 1819 GKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERER 1878

Query: 74   NYVPE------DEDLKKRRVPQAK 91
                E       E+ + R+V + K
Sbjct: 1879 KLREEHIRRQQKEEQRHRQVGEIK 1902



 Score = 27.3 bits (59), Expect = 7.2
 Identities = 20/86 (23%), Positives = 42/86 (48%), Gaps = 1/86 (1%)

Query: 24  LEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLK 83
           L+E+  + ++ L+   E+  R+++E    + +  +  EEE  +  E +L     E    +
Sbjct: 895 LQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQ 954

Query: 84  KRRVPQAKPVAVEEKVKEQLEAAKPE 109
           +R     K   +++K +EQL   +PE
Sbjct: 955 ERERQYRKDKKLQQK-EEQLLGEEPE 979


>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 899

 Score = 42.4 bits (98), Expect = 2e-04
 Identities = 36/160 (22%), Positives = 84/160 (52%), Gaps = 12/160 (7%)

Query: 23  RLEEEALR-RKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDED 81
           R EEE +R ++E+++   EK   ++++  E + K   +EE+  E+  ++    +  E++ 
Sbjct: 599 REEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKM----WEQEEKM 654

Query: 82  LKKRRVPQAKPVAVE-EKVKEQLEAAKPEPVI---EEVDLANLAPRKPDWDLKRDVAKKL 137
            +++R+P+ K    E EK++EQ +  + E  I   E+++       K  WD ++   ++ 
Sbjct: 655 WEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEES 714

Query: 138 EKLKKRTQRAIAELIR---ERLKGQEDSLASAVDAATEQK 174
            + +++  R   E++R   E+++ QE+ +    +   EQ+
Sbjct: 715 MREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQE 754



 Score = 39.3 bits (90), Expect = 0.002
 Identities = 39/147 (26%), Positives = 76/147 (51%), Gaps = 10/147 (6%)

Query: 24  LEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEE----EEGEK--HRELRLRNYVP 77
           L+EE  R++E L+  +EK  RK +E    + + LRE+E    E+ EK   +E RLR    
Sbjct: 270 LQEEMWRQEEELRE-QEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEK 328

Query: 78  EDEDLKKRRVPQAKPVAVEEKVKEQLEAA-KPEPVIEEVDLANLAPRKPDWDLKRDVAKK 136
           E  + +K    Q +    EE+++EQ E   + E  + E +       +  W+ ++ + ++
Sbjct: 329 ELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQ 388

Query: 137 LEKLKKRTQRAIAELIRERLKGQEDSL 163
            +K++ + +R   +   ERL+ +E+ +
Sbjct: 389 EQKMRDQEERMWEQ--DERLREKEERM 413



 Score = 38.1 bits (87), Expect = 0.004
 Identities = 39/150 (26%), Positives = 75/150 (50%), Gaps = 13/150 (8%)

Query: 21  VGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEE-GEKHRELRLRNYVPED 79
           + + EE+  R++ERL+  +E   R+ +E    + K LRE+E+E  E+ +ELR +  + E 
Sbjct: 288 IRKQEEKMWRQEERLRE-QEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQ 346

Query: 80  EDLKKRRVPQAKPVAVEEKVKEQLEAA--------KPEPVIEEVDLANLAPRKPDWDLKR 131
           E+  + +  + K    EEK++EQ E          + E  + E +       +  W+   
Sbjct: 347 EEQMQEQ--EEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDE 404

Query: 132 DVAKKLEKLKKRTQR-AIAELIRERLKGQE 160
            + +K E+++++ +     E +RE  K QE
Sbjct: 405 RLREKEERMREQEKMWEQVEKMREEKKMQE 434



 Score = 36.2 bits (82), Expect = 0.015
 Identities = 33/141 (23%), Positives = 77/141 (54%), Gaps = 20/141 (14%)

Query: 23  RLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDL 82
           R +EE ++ +ER++  REK  R+++E        +RE+EE+ +K  E     +  E+++ 
Sbjct: 440 RDQEEKMQEEERIRE-REKKMREEEET-------MREQEEKMQKQEE---NMWEQEEKEW 488

Query: 83  KKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKK 142
           +++R+P+ K     EK+ EQ +  + E  I E +   +  ++  W  ++ + ++ EK+++
Sbjct: 489 QQQRLPEQK-----EKLWEQEKMQEQEEKIWEQE-EKIRDQEEMWGQEKKMWRQ-EKMRE 541

Query: 143 RTQRAIAELIRERLKGQEDSL 163
           +  +   +   E+++ QE  +
Sbjct: 542 QEDQMWEQ--EEKMRDQEQKM 560



 Score = 34.7 bits (78), Expect = 0.045
 Identities = 34/164 (20%), Positives = 76/164 (46%), Gaps = 16/164 (9%)

Query: 25  EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKK 84
           EEE +R +E+     E+T R+ +E  + + +++ E+EE  ++ ++ RL     +  + +K
Sbjct: 448 EEERIREREKKMREEEETMREQEEKMQKQEENMWEQEE--KEWQQQRLPEQKEKLWEQEK 505

Query: 85  RRVPQAKPVAVEEKVKEQLE-------------AAKPEPVIEEVDLANLAPRKPDWDLKR 131
            +  + K    EEK+++Q E               + E  + E +       +  WD + 
Sbjct: 506 MQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEE 565

Query: 132 DVAKKLEKLKKRTQRAIAEL-IRERLKGQEDSLASAVDAATEQK 174
            + KK ++ +K+T     ++   ER++ +E  +    +   EQ+
Sbjct: 566 RMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQE 609



 Score = 34.3 bits (77), Expect = 0.059
 Identities = 28/151 (18%), Positives = 68/151 (45%), Gaps = 4/151 (2%)

Query: 13  KMEATTAGVGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRL 72
           KM+     +   E+   + +E+ K   ++   +++E    + K +REEEE   +  E   
Sbjct: 678 KMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQ 737

Query: 73  RNYVPEDEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRD 132
                  E  ++    + K    EEK+ EQ    + +  + E +   +  ++  W+ +  
Sbjct: 738 EQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHE--KMQEQEKIWEQEEK 795

Query: 133 VAKKLEKLKKRTQRAIAELIRERLKGQEDSL 163
           +  + EK++ + ++   +   E+++GQE+ +
Sbjct: 796 MRDQEEKMRGQEEKMRGQ--EEKMRGQEEKM 824



 Score = 31.6 bits (70), Expect = 0.38
 Identities = 44/181 (24%), Positives = 84/181 (46%), Gaps = 29/181 (16%)

Query: 20  GVGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEE-----------EEGEKHR 68
           G  R +EE + R+E+    +EK  R+ +++   + K LRE+E           E+ EK R
Sbjct: 307 GKMREQEEKMWRQEKRLREQEKELREQEKELR-EQKELREQEEQMQEQEEKMWEQEEKMR 365

Query: 69  ELRLRNYVPED---EDLKKRRVPQAKPVAVEEKVKEQLEAAK--------PEPVIEEVDL 117
           E   + +  E+   E  K+ R  + K    EE++ EQ E  +         E + E+V+ 
Sbjct: 366 EQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEK 425

Query: 118 ANLAPRKPDWDLK-RDVAKKL---EKLKKRTQRAIAELIRERLKGQEDSLASAVDAATEQ 173
                +  + + K RD  +K+   E++++R ++   E   E ++ QE+ +    +   EQ
Sbjct: 426 MREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREE--EETMREQEEKMQKQEENMWEQ 483

Query: 174 K 174
           +
Sbjct: 484 E 484



 Score = 31.2 bits (69), Expect = 0.50
 Identities = 24/90 (26%), Positives = 46/90 (51%), Gaps = 10/90 (11%)

Query: 25  EEEALRRKERLKALREKTGRKDKEDGEPKT----KHLREEEEEGEKHRELRLRNYVPEDE 80
           +EE +R +E+    +E+   K  ++ E KT    + +REEE   E+ +++R    +  ++
Sbjct: 549 QEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQ 608

Query: 81  DLK------KRRVPQAKPVAVEEKVKEQLE 104
           + K      K +  + K    EEK++EQ E
Sbjct: 609 EEKMQEQEEKMQEQEEKMWEQEEKMQEQEE 638



 Score = 28.9 bits (63), Expect = 2.5
 Identities = 33/145 (22%), Positives = 71/145 (48%), Gaps = 18/145 (12%)

Query: 25  EEEALRRKERL----KALREKTGR-KDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPED 79
           EE+  R++ERL    K +RE+  + +D+E+   +      E+EE  + +E ++   V + 
Sbjct: 368 EEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQE-KMWEQVEKM 426

Query: 80  EDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEK 139
            + KK +  + K    EEK++E+    + E  + E +           +  R+  +K++K
Sbjct: 427 REEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEE-----------ETMREQEEKMQK 475

Query: 140 LKKRT-QRAIAELIRERLKGQEDSL 163
            ++   ++   E  ++RL  Q++ L
Sbjct: 476 QEENMWEQEEKEWQQQRLPEQKEKL 500


>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 828

 Score = 42.4 bits (98), Expect = 2e-04
 Identities = 39/147 (26%), Positives = 75/147 (51%), Gaps = 10/147 (6%)

Query: 24  LEEEALRRKERLKALREKTGRKDKEDGEPKTKHLRE------EEEEGEKHRELRLRNYVP 77
           L+EE  R++E L+  +EK  RK +E    + + LRE      E+EE  + +E RLR    
Sbjct: 232 LQEEMWRQEEELRE-QEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEK 290

Query: 78  EDEDLKKRRVPQAKPVAVEEKVKEQLEAA-KPEPVIEEVDLANLAPRKPDWDLKRDVAKK 136
           E  + +K    Q K    EE+++EQ E   + E  + E +       +  W+ ++ + ++
Sbjct: 291 ELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQ 350

Query: 137 LEKLKKRTQRAIAELIRERLKGQEDSL 163
            +K++ + +R   +   ERL+ +E+ +
Sbjct: 351 EQKMRDQEERMWEQ--DERLREKEERM 375



 Score = 38.1 bits (87), Expect = 0.004
 Identities = 33/147 (22%), Positives = 71/147 (48%), Gaps = 10/147 (6%)

Query: 25  EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKK 84
           +EE +R +++ +   +KT   D+E+   + + +RE E++  +  E+         E  +K
Sbjct: 532 QEEKMREEKKTQEQEKKTW--DQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEK 589

Query: 85  RRVPQAKPVAVEEKVKEQLEA--AKPEPVIEEVDLANLAPRKP-DWDLKRDVAKKLEKL- 140
            R  + K    EEK++EQ E    + E + E+ +   +  ++   W+ +  + ++ EK+ 
Sbjct: 590 MREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMW 649

Query: 141 ----KKRTQRAIAELIRERLKGQEDSL 163
               K R Q        E+++GQE+ +
Sbjct: 650 EQEEKMREQEEKMREQEEKMQGQEEKM 676



 Score = 37.7 bits (86), Expect = 0.005
 Identities = 34/155 (21%), Positives = 79/155 (50%), Gaps = 13/155 (8%)

Query: 23  RLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEE----EEGEKHRELRLRNYVPE 78
           RL E+  R +E+ K   ++   +++E    + K +REEE    E+ EK ++     +  E
Sbjct: 367 RLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQE 426

Query: 79  DEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLE 138
           +++ +++R+P+ K     EK+ EQ +  + E  I E +   +  ++  W  ++ + ++ E
Sbjct: 427 EKEWQQQRLPEQK-----EKLWEQEKMQEQEEKIWEQE-EKIRDQEEMWGQEKKMWRQ-E 479

Query: 139 KLKKRTQRAIAELIRERLKGQEDSLASAVDAATEQ 173
           K++++  +   +   E+++ QE  +    +   EQ
Sbjct: 480 KMREQEDQMWEQ--EEKMRDQEQKMWDQEERMWEQ 512



 Score = 37.4 bits (85), Expect = 0.007
 Identities = 34/153 (22%), Positives = 76/153 (49%), Gaps = 11/153 (7%)

Query: 23  RLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDL 82
           R +EE +R ++++    EK  R++K+  E + K   +EE+  E+ R       + E+E++
Sbjct: 517 REKEERMREQKKMWQQEEKM-REEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEM 575

Query: 83  KKRRVPQAKPVAVEEKVKEQLEAA-KPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLK 141
            + +  + K    EEK++EQ E   + E  ++E +       +  W+ +  + ++ E+ K
Sbjct: 576 MREQ--EEKMQEQEEKMREQEEKMWEQEEKMQEQE-------EKMWEQEEKMWEQEEEDK 626

Query: 142 KRTQRAIAELIRERLKGQEDSLASAVDAATEQK 174
            + Q  +     E+++ QE+ +    +   EQ+
Sbjct: 627 MQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQE 659



 Score = 36.6 bits (83), Expect = 0.012
 Identities = 34/162 (20%), Positives = 77/162 (47%), Gaps = 12/162 (7%)

Query: 23  RLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEE----EEGEKHRELRLRNYVPE 78
           ++ EE   +++  K   ++   +++E    + K +REEE    E+ EK +E   +    E
Sbjct: 535 KMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQE 594

Query: 79  D---EDLKKRRVPQAKPVAVEEKVKEQLEAAK---PEPVIEEVDLANLAPRKPDWDLKRD 132
           +   E  +K +  + K    EEK+ EQ E  K    E ++ E +       +  W+ +  
Sbjct: 595 EKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEK 654

Query: 133 VAKKLEKLKKRTQRAIAELIRERLKGQEDSLASAVDAATEQK 174
           + ++ EK++++ ++   +   E+++ QE+ +    +   EQ+
Sbjct: 655 MREQEEKMREQEEKMQGQ--EEKMREQEEKMQGQEEKMREQE 694



 Score = 33.9 bits (76), Expect = 0.077
 Identities = 41/168 (24%), Positives = 81/168 (48%), Gaps = 23/168 (13%)

Query: 20  GVGRLEEEALRRKE-RLKALREKTGRKDKEDGEPKTKHLREEE---------EEGEKHRE 69
           G  R +EE +RR+E RL+   ++   ++KE  E K    +EE+         E+ EK RE
Sbjct: 269 GKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMRE 328

Query: 70  LRLRNYVPED---EDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPD 126
              + +  E+   E  K+ R  + K    EE++ EQ E  + +   EE     +  ++  
Sbjct: 329 QEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREK---EE----RMREQEKM 381

Query: 127 WDLKRDVAKKLEKLKKRTQRAIAELIRERLKGQEDSLASAVDAATEQK 174
           W+ +  + ++ E++++R ++   E   E ++ QE+ +    +   EQ+
Sbjct: 382 WEQEEKMQEE-ERIREREKKMREE--EETMREQEEKMQKQEENMWEQE 426



 Score = 33.5 bits (75), Expect = 0.100
 Identities = 38/156 (24%), Positives = 73/156 (46%), Gaps = 24/156 (15%)

Query: 25  EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKK 84
           EEE +R +E+     E+T R+ +E  + + +++ E+EE+  + + L      PE    K+
Sbjct: 390 EEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRL------PEQ---KE 440

Query: 85  RRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDW------DLKRDVAKKLE 138
           +   Q K    EEK+ EQ E  + +   EE+        K  W      + +  + ++ E
Sbjct: 441 KLWEQEKMQEQEEKIWEQEEKIRDQ---EEM----WGQEKKMWRQEKMREQEDQMWEQEE 493

Query: 139 KLKKRTQRAIAELIRERLKGQEDSLASAVDAATEQK 174
           K++ + Q+   +   ER+  Q++ L    +   EQK
Sbjct: 494 KMRDQEQKMWDQ--EERMWEQDERLREKEERMREQK 527



 Score = 32.7 bits (73), Expect = 0.17
 Identities = 34/163 (20%), Positives = 72/163 (44%), Gaps = 3/163 (1%)

Query: 13  KMEATTAGVGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRL 72
           KM      +   EE+   ++E++    EK   +++ED   + + +  E+EE  + +E ++
Sbjct: 589 KMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKM 648

Query: 73  RNYVPE-DEDLKKRRVPQAKPVAVEEKVKEQLEAAK-PEPVIEEVDLANLAPRKPDWDLK 130
                +  E  +K R  + K    EEK++EQ E  +  E  + E +       +  W  +
Sbjct: 649 WEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQE 708

Query: 131 RDVAKKLEKL-KKRTQRAIAELIRERLKGQEDSLASAVDAATE 172
             +  + EK+  +   R   E IR++ +  ++ L    +  +E
Sbjct: 709 EKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEERCSE 751



 Score = 31.2 bits (69), Expect = 0.50
 Identities = 26/155 (16%), Positives = 75/155 (48%), Gaps = 5/155 (3%)

Query: 25  EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDE---- 80
           +EE +R +E+    +E+   +  E    K + +RE+++  ++  ++R      E E    
Sbjct: 491 QEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTW 550

Query: 81  DLKKRRVPQAKPVAVEEKVKEQLEAAK-PEPVIEEVDLANLAPRKPDWDLKRDVAKKLEK 139
           D +++   + +    E+K++E+ E  +  E  ++E +       +  W+ +  + ++ EK
Sbjct: 551 DQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEK 610

Query: 140 LKKRTQRAIAELIRERLKGQEDSLASAVDAATEQK 174
           + ++ ++   +   ++++ QE+ +    +   EQ+
Sbjct: 611 MWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQE 645



 Score = 27.3 bits (59), Expect = 7.2
 Identities = 31/140 (22%), Positives = 70/140 (50%), Gaps = 11/140 (7%)

Query: 25  EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEE-GEKHRELRLRNYVPEDEDLK 83
           +EE L  +E+    +E+  R  +E    + + LRE+EE   E+ +       + E+E ++
Sbjct: 336 QEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIR 395

Query: 84  KRRVPQAKPVAVEEKVKEQLE--AAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLK 141
           +R   + K    EE ++EQ E    + E + E+ +      R P+   +++   + EK++
Sbjct: 396 ER---EKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPE---QKEKLWEQEKMQ 449

Query: 142 KRTQRAIAELIRERLKGQED 161
           ++ ++   +   E+++ QE+
Sbjct: 450 EQEEKIWEQ--EEKIRDQEE 467


>gi|154354979 myosin X [Homo sapiens]
          Length = 2058

 Score = 42.4 bits (98), Expect = 2e-04
 Identities = 36/143 (25%), Positives = 67/143 (46%), Gaps = 7/143 (4%)

Query: 29  LRRKERLKALREKTGRKDKEDGEPKTKHLREEEE-EGEKHRELRLRNYVPEDEDLKKRRV 87
           + R+   + L EK  +++K+  E + K  REEEE E E+ R         E+E  K++ +
Sbjct: 803 IARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQEL 862

Query: 88  PQAKPVAVEEKVKEQLEAAKPEPVIEEV-----DLANLAPRKPDWDLKRDVAKKLEKLKK 142
              +    E ++  +LE  K    +EE+     ++ +L   K   +L    A  L+KL++
Sbjct: 863 EALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEA-SLQKLQE 921

Query: 143 RTQRAIAELIRERLKGQEDSLAS 165
           R  + +  L  E  +  ++ L S
Sbjct: 922 RRDQELRRLEEEACRAAQEFLES 944



 Score = 34.3 bits (77), Expect = 0.059
 Identities = 32/131 (24%), Positives = 63/131 (48%), Gaps = 5/131 (3%)

Query: 23  RLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLR-EEEEEGEKHRELRLRNYVPEDED 81
           R +EE  +++E  K  RE+  R+   + E +   LR ++EEE  K +EL       ++ +
Sbjct: 816 REQEEKKKQEEEEKKKREEEERE--RERERREAELRAQQEEETRKQQELEALQKSQKEAE 873

Query: 82  LKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLK 141
           L +    Q +   VEE ++ + E    + + E+ +L+           +RD  ++L +L+
Sbjct: 874 LTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRD--QELRRLE 931

Query: 142 KRTQRAIAELI 152
           +   RA  E +
Sbjct: 932 EEACRAAQEFL 942


>gi|104526627 triadin [Homo sapiens]
          Length = 729

 Score = 42.4 bits (98), Expect = 2e-04
 Identities = 36/135 (26%), Positives = 61/135 (45%), Gaps = 18/135 (13%)

Query: 22  GRLEEEALRRKERLKALREKTGR-----------KDKEDGEPKTKHLREEEEEGEKHREL 70
           G ++E  LR+KE  K   EK  +           K+KE G+ K +  +E+ E+   H+E 
Sbjct: 131 GEIDEPPLRKKEIHKDKTEKQEKPERKIQTKVTHKEKEKGKEKVRE-KEKPEKKATHKEK 189

Query: 71  RLRNYVPEDEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPV------IEEVDLANLAPRK 124
             +   PE + L K +         EEK K++++  K E V      ++EV      P++
Sbjct: 190 IEKKEKPETKTLAKEQKKAKTAEKSEEKTKKEVKGGKQEKVKQTAAKVKEVQKTPSKPKE 249

Query: 125 PDWDLKRDVAKKLEK 139
            +   K  V+K  +K
Sbjct: 250 KEDKEKAAVSKHEQK 264



 Score = 40.4 bits (93), Expect = 8e-04
 Identities = 36/156 (23%), Positives = 70/156 (44%), Gaps = 21/156 (13%)

Query: 12  GKMEATTAGVGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELR 71
           GK   T  G  ++  +A  +K+            +K++   KTK   E E+   K +E +
Sbjct: 353 GKASETKQGTVKIAAQAAAKKD------------EKKEDSKKTKKPAEVEQPKGKKQEKK 400

Query: 72  LRNYVPEDEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKR 131
            ++  P     K+  VP       +++VK + E AK E  I  V +    P K +    +
Sbjct: 401 EKHVEPAKSPKKEHSVPS------DKQVKAKTERAKEE--IGAVSIKKAVPGKKEEKTTK 452

Query: 132 DVAKKLEKLKKRTQRAIAELIRERLKGQEDSLASAV 167
            V +++ K K     +I +  +E +KG+E+ + +++
Sbjct: 453 TVEQEIRKEKSGKTSSILK-DKEPIKGKEEKVPASL 487



 Score = 30.4 bits (67), Expect = 0.85
 Identities = 39/163 (23%), Positives = 66/163 (40%), Gaps = 22/163 (13%)

Query: 26  EEALRRKERLKALREKTGRKDKED----GEPKTKHLREEEEEGEKHRELRLRNYVP-EDE 80
           E+A R      AL EK G K K +     E K K   + +++ EK   + +    P +  
Sbjct: 297 EQASRPTPASPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEKKEPGKAS 356

Query: 81  DLKKRRVPQAKPVAVE--------EKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRD 132
           + K+  V  A   A +        +K K+  E  +P+   +E    ++ P K     K  
Sbjct: 357 ETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQEKKEKHVEPAKS--PKKEH 414

Query: 133 VAKKLEKLKKRTQRAIAELIRERLKGQEDSLASAVDAATEQKT 175
                +++K +T+RA  E+          S+  AV    E+KT
Sbjct: 415 SVPSDKQVKAKTERAKEEI-------GAVSIKKAVPGKKEEKT 450


>gi|4505101 microtubule-associated protein 7 [Homo sapiens]
          Length = 749

 Score = 42.0 bits (97), Expect = 3e-04
 Identities = 37/163 (22%), Positives = 75/163 (46%), Gaps = 11/163 (6%)

Query: 17  TTAGVGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYV 76
           T+AG    EE      E+ +  RE+  ++++E         R E+EE E+ +   L   V
Sbjct: 469 TSAGTTDPEEATRLLAEKRRLAREQREKEERE---------RREQEELERQKREELAQRV 519

Query: 77  PEDEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLK-RDVAK 135
            E+   ++    +        + +EQL+    E  + E + A  A R+ + + + R+ A+
Sbjct: 520 AEERTTRREEESRRLEAEQAREKEEQLQRQAEERALREREEAERAQRQKEEEARVREEAE 579

Query: 136 KL-EKLKKRTQRAIAELIRERLKGQEDSLASAVDAATEQKTCD 177
           ++ ++ +K  QR   E +  + + +E    +    AT++KT D
Sbjct: 580 RVRQEREKHFQREEQERLERKKRLEEIMKRTRRTEATDKKTSD 622



 Score = 39.3 bits (90), Expect = 0.002
 Identities = 37/154 (24%), Positives = 70/154 (45%), Gaps = 20/154 (12%)

Query: 23  RLEEEALRRKER----LKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPE 78
           R E+E L R++R     +   E+T R+++E    + +  RE+EE+ ++  E R      E
Sbjct: 501 RREQEELERQKREELAQRVAEERTTRREEESRRLEAEQAREKEEQLQRQAEERALREREE 560

Query: 79  DEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLE 138
            E  ++++  +A+     E+V+++ E        E ++      RK          K+LE
Sbjct: 561 AERAQRQKEEEARVREEAERVRQEREKHFQREEQERLE------RK----------KRLE 604

Query: 139 KLKKRTQRAIAELIRERLKGQEDSLASAVDAATE 172
           ++ KRT+R  A   +   +   D    A+   TE
Sbjct: 605 EIMKRTRRTEATDKKTSDQRNGDIAKGALTGGTE 638



 Score = 26.9 bits (58), Expect = 9.4
 Identities = 14/47 (29%), Positives = 25/47 (53%)

Query: 23  RLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRE 69
           RLEE+  + + R  A+ EK  ++ +ED E     +R   E  +K ++
Sbjct: 109 RLEEQRQKEERRRAAVEEKRRQRLEEDKERHEAVVRRTMERSQKPKQ 155


>gi|22027541 programmed cell death 7 [Homo sapiens]
          Length = 485

 Score = 42.0 bits (97), Expect = 3e-04
 Identities = 39/123 (31%), Positives = 56/123 (45%), Gaps = 15/123 (12%)

Query: 33  ERLKALREKT----GRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKKRRVP 88
           ERL+ L +       R+  E    +   LRE   E E  RE      V  ++++ + RV 
Sbjct: 221 ERLQPLTQAAYVGEARRRLERVRRRRLRLRERAREREAEREAEAARAVEREQEIDRWRVK 280

Query: 89  QAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKR--DVAKKLEKLKKRTQR 146
             + V  EEK +EQ   A  + V+ EV       RK   D KR  D+ + LEKL+K  + 
Sbjct: 281 CVQEV--EEKKREQELKAAADGVLSEV-------RKKQADTKRMVDILRALEKLRKLRKE 331

Query: 147 AIA 149
           A A
Sbjct: 332 AAA 334


>gi|22758136 MAP7 domain containing 2 [Homo sapiens]
          Length = 732

 Score = 42.0 bits (97), Expect = 3e-04
 Identities = 36/154 (23%), Positives = 76/154 (49%), Gaps = 5/154 (3%)

Query: 23  RLEEEALRRKERLKALR-EKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDED 81
           RLE E L+RK   + LR E+  RK +E+ + + +  +++E E ++      +    E+  
Sbjct: 430 RLEREELKRKAEEERLRLEEEARKQEEERKRQEEEKKKQEGEEKRKAGEEAKRKAEEELL 489

Query: 82  LKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLK 141
           LK+++  + +  A+ EK KE  E  K   V E++ L            + +  K+++++ 
Sbjct: 490 LKEKQEQEKQEKAMIEKQKEAAE-TKAREVAEQMRLEREQIMLQIEQERLERKKRIDEIM 548

Query: 142 KRTQRAIAELIRERLKGQEDSLASAVDAATEQKT 175
           KRT+++    +  ++K ++  +        E+KT
Sbjct: 549 KRTRKSD---VPPQVKKEDPKVGVQPAVCVEKKT 579



 Score = 36.6 bits (83), Expect = 0.012
 Identities = 39/162 (24%), Positives = 74/162 (45%), Gaps = 14/162 (8%)

Query: 6   KGGAYAGKMEATTAGVGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGE 65
           +  A  GK  A T   G   +  L  K R   L+++   +++ + E + +  REE +   
Sbjct: 382 ENSAALGKPTAGTTDAGEAAK-ILAEKRRQARLQKEQEEQERVEKEEQDRLEREELKRKA 440

Query: 66  KHRELRLRNYVPEDEDLKKRRVPQAKPVAVEEKVKEQLEA---------AKPEPVIEEVD 116
           +   LRL     + E+ +KR+  + K    EEK K   EA          K +   E+ +
Sbjct: 441 EEERLRLEEEARKQEEERKRQEEEKKKQEGEEKRKAGEEAKRKAEEELLLKEKQEQEKQE 500

Query: 117 LANLAPRKPDWDLK-RDVAKKLEKLKKRTQRAIAELIRERLK 157
            A +  +K   + K R+VA   E+++   ++ + ++ +ERL+
Sbjct: 501 KAMIEKQKEAAETKAREVA---EQMRLEREQIMLQIEQERLE 539



 Score = 31.6 bits (70), Expect = 0.38
 Identities = 35/148 (23%), Positives = 63/148 (42%), Gaps = 10/148 (6%)

Query: 6   KGGAYAGKMEATTAGVGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGE 65
           K  A AG     +A +G+         E  K L EK  +   +  + + + + +EE++  
Sbjct: 372 KHAAAAGGKAENSAALGKPTAGTTDAGEAAKILAEKRRQARLQKEQEEQERVEKEEQDRL 431

Query: 66  KHRELRLRNYVPEDEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKP 125
           +  EL+ +    E+E L+     + +    EE+ K Q E  K +   E+      A RK 
Sbjct: 432 EREELKRK---AEEERLRLEEEARKQ----EEERKRQEEEKKKQEGEEKRKAGEEAKRKA 484

Query: 126 DWDL---KRDVAKKLEKLKKRTQRAIAE 150
           + +L   ++   +K EK     Q+  AE
Sbjct: 485 EEELLLKEKQEQEKQEKAMIEKQKEAAE 512


>gi|41152097 DNA segment on chromosome X and Y (unique) 155
           expressed sequence isoform 1 [Homo sapiens]
          Length = 695

 Score = 40.8 bits (94), Expect = 6e-04
 Identities = 41/177 (23%), Positives = 84/177 (47%), Gaps = 16/177 (9%)

Query: 1   MQDGRKGGAYAGKMEATTAGVGRLEEEALRRKE-------RLKALREKTGRKDKE----- 48
           M  G  G A A  ++ +      L + ++++++        L+  RE+  R++KE     
Sbjct: 240 MYKGEDGKAVACNIKVSFDSTKHLSDASIKKRQLERQKLQELEQQREEQKRREKEAEERQ 299

Query: 49  -DGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKKRRVPQAKPVAVEEK-VKEQLEAA 106
              E K K L E E E ++  +LR R     D +L++ +    K  A E+K ++E+++  
Sbjct: 300 RAEERKQKELEELERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLE 359

Query: 107 KPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKKRTQRAIAELIRERLKGQEDSL 163
           + + ++ + +L ++  R     L R  A KL + +++ ++   +   ER + QE  L
Sbjct: 360 ERKLLLAQRNLQSI--RLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAEL 414



 Score = 32.3 bits (72), Expect = 0.22
 Identities = 32/118 (27%), Positives = 58/118 (49%), Gaps = 13/118 (11%)

Query: 13  KMEATTAGVGRLEEEALRRKERLKALREKTGRKDKEDGE----PKTKHLREEEEEGEKHR 68
           K+E   A   +  +E ++ +ER   L ++  +  +   E     K   LRE+E++ EK  
Sbjct: 340 KLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQKEEK-- 397

Query: 69  ELRLRNYVPEDEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPD 126
            LRL+      +  ++RR+ +A+   VEE+ +  L   + E  + E  L+ L  +KPD
Sbjct: 398 -LRLQ------QQEERRRLQEAELRRVEEEKERALGLQRKERELRERLLSILLSKKPD 448


>gi|147903302 MAP7 domain containing 3 [Homo sapiens]
          Length = 876

 Score = 40.8 bits (94), Expect = 6e-04
 Identities = 40/141 (28%), Positives = 69/141 (48%), Gaps = 12/141 (8%)

Query: 11  AGKMEATTAGVGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHREL 70
           AG M A  A     E   L R++R K   E+   + ++    K+K + +E   G+    L
Sbjct: 591 AGIMNAEAATKILTELRRLAREQREKEEEERQREEMQQRVIKKSKDMAKEAVGGQAEDHL 650

Query: 71  RLRNYVPEDEDLKKR----RVPQAKPVAV-EEKVKEQLEAAKPEPVIEEVDLANLAPRKP 125
           +L++   ++E  KK+    +  Q  P+   + K+K Q EA K +   E + L NL  R  
Sbjct: 651 KLKDGQQQNETKKKKGWLDQEDQEAPLQKGDAKIKAQEEADKRKKEHERIMLQNLQER-- 708

Query: 126 DWDLKRDVAKKLEKLKKRTQR 146
              L+R   K++E++ KRT++
Sbjct: 709 ---LER--KKRIEEIMKRTRK 724


>gi|117553580 adaptor-related protein complex 3, delta 1 subunit
           isoform 2 [Homo sapiens]
          Length = 1153

 Score = 40.4 bits (93), Expect = 8e-04
 Identities = 48/166 (28%), Positives = 74/166 (44%), Gaps = 26/166 (15%)

Query: 23  RLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEG-------EKHRELRLRNY 75
           +LEEE   R++  K  R K  ++ ++ G+ +   L  E +E        +   E    N 
Sbjct: 726 KLEEERRHRQKLEKDKRRKKRKEKEKKGKRRHSSLPTESDEDIAPAQQVDIVTEEMPENA 785

Query: 76  VPEDEDLKKRRVPQA-------KPVAVEEKVKEQ----LEAAK-PEPVIEEVDLANLAPR 123
           +P DED K    P         KP+A  EK+  Q     E +K PE  +  V+  +  P+
Sbjct: 786 LPSDEDDKDPNDPYRALDIDLDKPLADSEKLPIQKHRNTETSKSPEKDVPMVEKKSKKPK 845

Query: 124 KPDWDLK---RDVAKKLEKLKKRTQRAIAELIR----ERLKGQEDS 162
           K +   K   RD  KK EK KK++ +   +  R    ER KG++ S
Sbjct: 846 KKEKKHKEKERDKEKKKEKEKKKSPKPKKKKHRKEKEERTKGKKKS 891



 Score = 28.9 bits (63), Expect = 2.5
 Identities = 33/153 (21%), Positives = 62/153 (40%), Gaps = 13/153 (8%)

Query: 30  RRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKKRRVPQ 89
           R  E  K+  +     +K+  +PK K  + +E+E +K ++             KK R  +
Sbjct: 822 RNTETSKSPEKDVPMVEKKSKKPKKKEKKHKEKERDKEKKKEKEKKKSPKPKKKKHRKEK 881

Query: 90  AKPVAVEEKVKEQ---LEAAKPEPVIEEVDLANLAPRKPDWDLKRD------VAKKLEKL 140
            +    ++K K+Q    E A  EPV          P +  + L  +             L
Sbjct: 882 EERTKGKKKSKKQPPGSEEAAGEPVQNGAPEEEQLPPESSYSLLAENSYVKMTCDIRGSL 941

Query: 141 KKRTQRAIAELIRER----LKGQEDSLASAVDA 169
           ++ +Q  +A ++  R    LKG E S+  +++A
Sbjct: 942 QEDSQVTVAIVLENRSSSILKGMELSVLDSLNA 974



 Score = 28.9 bits (63), Expect = 2.5
 Identities = 20/89 (22%), Positives = 43/89 (48%), Gaps = 10/89 (11%)

Query: 21  VGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDE 80
           V  +E+++ + K++ K  +EK   K+K+  + K K  + ++++  K +E          E
Sbjct: 834 VPMVEKKSKKPKKKEKKHKEKERDKEKKKEKEKKKSPKPKKKKHRKEKE----------E 883

Query: 81  DLKKRRVPQAKPVAVEEKVKEQLEAAKPE 109
             K ++  + +P   EE   E ++   PE
Sbjct: 884 RTKGKKKSKKQPPGSEEAAGEPVQNGAPE 912


>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 668

 Score = 40.0 bits (92), Expect = 0.001
 Identities = 30/150 (20%), Positives = 78/150 (52%), Gaps = 14/150 (9%)

Query: 23  RLEEEALRRKERLKALREKTGRKDK----EDGEPKTKHLREEEEEGEKH-----RELRLR 73
           RLEE    ++E+++ L EK   ++K    E+   + + +RE+E+  E+      +E ++R
Sbjct: 367 RLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIR 426

Query: 74  NYVPEDEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDV 133
               +  + +K+   Q + +  +EK++E+ +  + E +  + +   +  ++  W  K  +
Sbjct: 427 EQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEE--KIREQEEIWRQKEKM 484

Query: 134 AKKLEKLKKRTQRAIAELIRERLKGQEDSL 163
            ++ EK++K+ ++   +   E++  QE+ +
Sbjct: 485 HEQ-EKIRKQEEKVWRQ--EEKMHDQEEKI 511



 Score = 39.3 bits (90), Expect = 0.002
 Identities = 36/158 (22%), Positives = 73/158 (46%), Gaps = 21/158 (13%)

Query: 23  RLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDL 82
           R EE+    +E+++   EK   ++++  E + K  R+EE   EK  ++R +  +  +++ 
Sbjct: 304 RQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 363

Query: 83  KKRRVPQ------------AKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLK 130
           K RR+ +             + +  +EK++EQ E  + E  I E +       K  W  +
Sbjct: 364 KMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKM-WRQE 422

Query: 131 RDVAKKLEKLKKRTQRA--------IAELIRERLKGQE 160
             + ++ EK++++ ++           E IRE  K QE
Sbjct: 423 EKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQE 460



 Score = 38.9 bits (89), Expect = 0.002
 Identities = 28/135 (20%), Positives = 67/135 (49%), Gaps = 3/135 (2%)

Query: 13  KMEATTAGVGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRL 72
           KM      +   EE+  R++E+++   EK   ++++  E +     +EE+ GE+  +++ 
Sbjct: 503 KMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQE 562

Query: 73  RNYVPEDEDLKKRRVPQAKPVAVEEKVKEQLEAA-KPEPVIEEVDLANLAPRKPDWDLKR 131
           +  +   E+  K R  + K    +EK++EQ E   + E  I E +       +  W+ + 
Sbjct: 563 QEKMRRQEE--KIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEE 620

Query: 132 DVAKKLEKLKKRTQR 146
            + ++ EK++++ ++
Sbjct: 621 KMCEQEEKMQEQEEK 635



 Score = 35.0 bits (79), Expect = 0.034
 Identities = 31/154 (20%), Positives = 74/154 (48%), Gaps = 10/154 (6%)

Query: 21  VGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDE 80
           + + EE+  R++E++    EK   ++++    + K   +EE+  E+  ++R      E E
Sbjct: 490 IRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIR------EQE 543

Query: 81  DLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKL 140
           ++ + +  + K    EEK++EQ +  + E  I E +      ++   + +  + ++ EK+
Sbjct: 544 EMMQEQ--EEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKI 601

Query: 141 KKRTQRAIAELIRERLKGQEDSLASAVDAATEQK 174
             R Q  + +   E++  QE+ +    +   EQ+
Sbjct: 602 --REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQE 633



 Score = 29.6 bits (65), Expect = 1.4
 Identities = 31/150 (20%), Positives = 73/150 (48%), Gaps = 26/150 (17%)

Query: 23  RLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDL 82
           R +EE ++ +E      EK G ++ E  + + K  R+EE+  E+  ++R        E  
Sbjct: 540 REQEEMMQEQE------EKMGEQE-EKMQEQEKMRRQEEKIREQEEKIR--------EQK 584

Query: 83  KKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKK 142
           +K R  + K    EEK++EQ      E +++E +       +   + +  + ++ EK+++
Sbjct: 585 EKIREQEEKIWEQEEKIREQ------EEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRR 638

Query: 143 RTQRAIAELIR-----ERLKGQEDSLASAV 167
           + ++   + +R     E+++  ++ L +A+
Sbjct: 639 QEEKMWEQEVRLRQQEEKMQEHQEHLEAAI 668



 Score = 27.3 bits (59), Expect = 7.2
 Identities = 20/90 (22%), Positives = 42/90 (46%), Gaps = 8/90 (8%)

Query: 13  KMEATTAGVGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRL 72
           KM      +   EE+   +KE+++   EK   ++++  E +     +EE+  E+  ++  
Sbjct: 565 KMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCE 624

Query: 73  RNYVPEDEDLKKRRVPQAKPVAVEEKVKEQ 102
           +    ++++ K RR         EEK+ EQ
Sbjct: 625 QEEKMQEQEEKMRR--------QEEKMWEQ 646


>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 275

 Score = 40.0 bits (92), Expect = 0.001
 Identities = 41/148 (27%), Positives = 65/148 (43%), Gaps = 24/148 (16%)

Query: 30  RRKERLKALREKTGRKDKEDG--EPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKKRRV 87
           R KER K  +EK  R+ K+ G  E K K  R+E E   K R  R R         KKRR 
Sbjct: 90  REKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKR---------KKRRK 140

Query: 88  PQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKKRTQRA 147
            + +     EK + + E  + +             +K + + KR+  +K E+ K+R ++ 
Sbjct: 141 KKRRKERKREKERGKRERKRKK------------RKKEEREKKRERNRK-ERKKERERKE 187

Query: 148 IAELIRERLKGQEDSLASAVDAATEQKT 175
             E  +ER K +        D  T+++T
Sbjct: 188 RRERKKERKKERRKKKERKKDRKTDRQT 215



 Score = 38.1 bits (87), Expect = 0.004
 Identities = 34/139 (24%), Positives = 64/139 (46%), Gaps = 13/139 (9%)

Query: 23  RLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDL 82
           R  E    R+ER K  RE+   + +E G+ + K  ++ E   E+ R+ + R     ++  
Sbjct: 32  RESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKER-----EKQR 86

Query: 83  KKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKK 142
           K+RR  + +    E+K +E+ +  + E   ++         K   + KR   KK  K K+
Sbjct: 87  KERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKR---KKRRKKKR 143

Query: 143 RTQRAIAELIRERLKGQED 161
           R +R      RE+ +G+ +
Sbjct: 144 RKERK-----REKERGKRE 157



 Score = 35.8 bits (81), Expect = 0.020
 Identities = 32/133 (24%), Positives = 61/133 (45%), Gaps = 3/133 (2%)

Query: 26  EEALRRKERLKALREKTGRKDKEDGEPKT--KHLREEEEEGEKHRELRLRNYVPEDEDLK 83
           E   R++ER K  + + G+K+K+  + +   K    + +E EK R+ R      + +  K
Sbjct: 42  EREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEK 101

Query: 84  KRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAK-KLEKLKK 142
           K+R  + +     +K KE+ E  +      E        +K   + KR+  + K E+ +K
Sbjct: 102 KKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRK 161

Query: 143 RTQRAIAELIRER 155
           + ++   E  RER
Sbjct: 162 KRKKEEREKKRER 174



 Score = 32.3 bits (72), Expect = 0.22
 Identities = 26/88 (29%), Positives = 46/88 (52%), Gaps = 6/88 (6%)

Query: 22  GRLEEEALR-RKERLKALREKTGRKDKEDGEPK-TKHLREEEEEGEKHRELRLRNYVPED 79
           GR E +  + RKER +  +++  RK K+  + K  K  + E+E G++ R+ + R    + 
Sbjct: 110 GRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKR----KK 165

Query: 80  EDLKKRRVPQAKPVAVEEKVKEQLEAAK 107
           E+ +K+R    K    E + KE+ E  K
Sbjct: 166 EEREKKRERNRKERKKERERKERRERKK 193



 Score = 30.8 bits (68), Expect = 0.65
 Identities = 26/119 (21%), Positives = 57/119 (47%), Gaps = 9/119 (7%)

Query: 25  EEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKK 84
           E++   RK+R +  RE+  +K++++ E + K  RE + +  + ++ R      ++   ++
Sbjct: 100 EKKKRERKQRGR--RERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRE 157

Query: 85  RRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKKR 143
           R+  + K    E+K +   +  K E   +E        R+   + K++  KK E+ K R
Sbjct: 158 RKRKKRKKEEREKKRERNRKERKKERERKE-------RRERKKERKKERRKKKERKKDR 209


>gi|88759339 aster-associated protein [Homo sapiens]
          Length = 647

 Score = 40.0 bits (92), Expect = 0.001
 Identities = 39/151 (25%), Positives = 66/151 (43%), Gaps = 9/151 (5%)

Query: 26  EEALRRKERLKALREKTGRK--DKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLK 83
           EEAL   E  KA++EK  +K   K+  E K K   EEE    K   L+        E  K
Sbjct: 467 EEALASFEAWKAMKEKEAKKIAAKKRLEEKNKKKTEEENAARKGEALQ------AFEKWK 520

Query: 84  KRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKKR 143
           ++++   K    +E+  E+ +  K E  + E    NL   +  W+ K++   K ++ +K 
Sbjct: 521 EKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVE-KWNEKKEAFFKQKEKEKI 579

Query: 144 TQRAIAELIRERLKGQEDSLASAVDAATEQK 174
            ++   EL R   K ++    +  +   E K
Sbjct: 580 NEKRKEELKRAEKKDKDKQAINEYEKWLENK 610


>gi|149589021 doublecortin-like kinase 3 [Homo sapiens]
          Length = 648

 Score = 39.7 bits (91), Expect = 0.001
 Identities = 44/170 (25%), Positives = 75/170 (44%), Gaps = 18/170 (10%)

Query: 11  AGKMEATTAGVGRLEEEALR--RKERLKALREKTGR---KDKEDGEPKTKHLREEEEEGE 65
           A K +     V  + EE LR  +K+     R K G    ++ + G  K +  R EE+E E
Sbjct: 239 AAKAKKDLVEVLPVTEEGLREVKKDTRPMSRSKHGGWLLREHQAGFEKLRRTRGEEKEAE 298

Query: 66  KHRELRL----RNYVPEDEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLA 121
           K ++  +    R  + +D+  K  + P+ +P   EE   E+    KP P+   +  AN+ 
Sbjct: 299 KEKKPCMSGGRRMTLRDDQPAKLEKEPKTRP---EENKPERPSGRKPRPM--GIIAANVE 353

Query: 122 PRKPDWDLKRD----VAKKLEKLKKRTQRAIAELIRERLKGQEDSLASAV 167
                  +  D    V K+    + R   A+  + + RLKG+ED + S +
Sbjct: 354 KHYETGRVIGDGNFAVVKECRHRETRQAYAMKIIDKSRLKGKEDMVDSEI 403


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.307    0.128    0.342 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,271,167
Number of Sequences: 37866
Number of extensions: 378911
Number of successful extensions: 6059
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 280
Number of HSP's successfully gapped in prelim test: 546
Number of HSP's that attempted gapping in prelim test: 2980
Number of HSP's gapped (non-prelim): 2312
length of query: 179
length of database: 18,247,518
effective HSP length: 96
effective length of query: 83
effective length of database: 14,612,382
effective search space: 1212827706
effective search space used: 1212827706
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 58 (26.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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