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Search of human proteins with 237858677
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|237858677 neurofascin isoform 2 precursor [Homo sapiens]
(1189 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|237858677 neurofascin isoform 2 precursor [Homo sapiens] 2441 0.0
gi|237858679 neurofascin isoform 3 precursor [Homo sapiens] 2402 0.0
gi|89903008 neurofascin isoform 4 precursor [Homo sapiens] 2387 0.0
gi|237858675 neurofascin isoform 1 precursor [Homo sapiens] 1684 0.0
gi|237858682 neurofascin isoform 6 precursor [Homo sapiens] 1231 0.0
gi|237858680 neurofascin isoform 5 precursor [Homo sapiens] 1224 0.0
gi|81158224 neuronal cell adhesion molecule isoform B precursor ... 1219 0.0
gi|81158226 neuronal cell adhesion molecule isoform A precursor ... 1037 0.0
gi|27894376 cell adhesion molecule with homology to L1CAM precur... 819 0.0
gi|221316760 L1 cell adhesion molecule isoform 3 precursor [Homo... 723 0.0
gi|13435353 L1 cell adhesion molecule isoform 2 precursor [Homo ... 716 0.0
gi|4557707 L1 cell adhesion molecule isoform 1 precursor [Homo s... 716 0.0
gi|28373129 contactin 5 isoform short [Homo sapiens] 361 3e-99
gi|7657359 contactin 5 isoform long [Homo sapiens] 360 6e-99
gi|28373122 contactin 4 isoform a precursor [Homo sapiens] 357 4e-98
gi|4827022 contactin 2 precursor [Homo sapiens] 357 5e-98
gi|28373117 contactin 1 isoform 1 precursor [Homo sapiens] 357 5e-98
gi|28373119 contactin 1 isoform 2 precursor [Homo sapiens] 357 5e-98
gi|75709184 contactin 3 [Homo sapiens] 355 2e-97
gi|7657361 contactin 6 [Homo sapiens] 311 2e-84
gi|119220552 sidekick 1 [Homo sapiens] 256 7e-68
gi|28373126 contactin 4 isoform c precursor [Homo sapiens] 256 1e-67
gi|222352127 sidekick 2 [Homo sapiens] 234 4e-61
gi|157311649 neogenin homolog 1 [Homo sapiens] 216 1e-55
gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42... 209 1e-53
gi|110431348 deleted in colorectal carcinoma [Homo sapiens] 202 2e-51
gi|21359935 Down syndrome cell adhesion molecule like 1 [Homo sa... 202 2e-51
gi|193083163 roundabout, axon guidance receptor, homolog 2 isofo... 193 9e-49
gi|61888896 roundabout, axon guidance receptor, homolog 2 isofor... 193 9e-49
gi|19743806 roundabout 1 isoform b [Homo sapiens] 187 4e-47
>gi|237858677 neurofascin isoform 2 precursor [Homo sapiens]
Length = 1189
Score = 2441 bits (6327), Expect = 0.0
Identities = 1189/1189 (100%), Positives = 1189/1189 (100%)
Query: 1 MARQPPPPWVHAAFLLCLLSLGGAIEIPMDLTQPPTITKQSAKDHIVDPRDNILIECEAK 60
MARQPPPPWVHAAFLLCLLSLGGAIEIPMDLTQPPTITKQSAKDHIVDPRDNILIECEAK
Sbjct: 1 MARQPPPPWVHAAFLLCLLSLGGAIEIPMDLTQPPTITKQSAKDHIVDPRDNILIECEAK 60
Query: 61 GNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGT 120
GNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGT
Sbjct: 61 GNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGT 120
Query: 121 ALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQD 180
ALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQD
Sbjct: 121 ALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQD 180
Query: 181 KRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRN 240
KRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRN
Sbjct: 181 KRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRN 240
Query: 241 HPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPS 300
HPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPS
Sbjct: 241 HPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPS 300
Query: 301 DKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILA 360
DKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILA
Sbjct: 301 DKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILA 360
Query: 361 PGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCN 420
PGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCN
Sbjct: 361 PGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCN 420
Query: 421 TSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQ 480
TSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQ
Sbjct: 421 TSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQ 480
Query: 481 GSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPE 540
GSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPE
Sbjct: 481 GSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPE 540
Query: 541 DQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGS 600
DQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGS
Sbjct: 541 DQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGS 600
Query: 601 YTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERSVRLTWI 660
YTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERSVRLTWI
Sbjct: 601 YTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERSVRLTWI 660
Query: 661 PGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVG 720
PGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVG
Sbjct: 661 PGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVG 720
Query: 721 SSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRR 780
SSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRR
Sbjct: 721 SSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRR 780
Query: 781 RETREAWNNVTVWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDYPRAAP 840
RETREAWNNVTVWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDYPRAAP
Sbjct: 781 RETREAWNNVTVWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDYPRAAP 840
Query: 841 TEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQASFPGD 900
TEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQASFPGD
Sbjct: 841 TEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQASFPGD 900
Query: 901 RLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSETKEFTTPEGVPSAPRRFRVRQPNLETIN 960
RLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSETKEFTTPEGVPSAPRRFRVRQPNLETIN
Sbjct: 901 RLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSETKEFTTPEGVPSAPRRFRVRQPNLETIN 960
Query: 961 LEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSA 1020
LEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSA
Sbjct: 961 LEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSA 1020
Query: 1021 RTQVGSGEAVTEESPAPPNEATPTAAYTNNQADIATQGWFIGLMCAIALLVLILLIVCFI 1080
RTQVGSGEAVTEESPAPPNEATPTAAYTNNQADIATQGWFIGLMCAIALLVLILLIVCFI
Sbjct: 1021 RTQVGSGEAVTEESPAPPNEATPTAAYTNNQADIATQGWFIGLMCAIALLVLILLIVCFI 1080
Query: 1081 KRSRGGKYPVREKKDVPLGPEDPKEEDGSFDYSDEDNKPLQGSQTSLDGTIKQQESDDSL 1140
KRSRGGKYPVREKKDVPLGPEDPKEEDGSFDYSDEDNKPLQGSQTSLDGTIKQQESDDSL
Sbjct: 1081 KRSRGGKYPVREKKDVPLGPEDPKEEDGSFDYSDEDNKPLQGSQTSLDGTIKQQESDDSL 1140
Query: 1141 VDYGEGGEGQFNEDGSFIGQYTVKKDKEETEGNESSEATSPVNAIYSLA 1189
VDYGEGGEGQFNEDGSFIGQYTVKKDKEETEGNESSEATSPVNAIYSLA
Sbjct: 1141 VDYGEGGEGQFNEDGSFIGQYTVKKDKEETEGNESSEATSPVNAIYSLA 1189
>gi|237858679 neurofascin isoform 3 precursor [Homo sapiens]
Length = 1174
Score = 2402 bits (6226), Expect = 0.0
Identities = 1174/1189 (98%), Positives = 1174/1189 (98%), Gaps = 15/1189 (1%)
Query: 1 MARQPPPPWVHAAFLLCLLSLGGAIEIPMDLTQPPTITKQSAKDHIVDPRDNILIECEAK 60
MARQPPPPWVHAAFLLCLLSLGGAIEIPMDLTQPPTITKQSAKDHIVDPRDNILIECEAK
Sbjct: 1 MARQPPPPWVHAAFLLCLLSLGGAIEIPMDLTQPPTITKQSAKDHIVDPRDNILIECEAK 60
Query: 61 GNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGT 120
GNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGT
Sbjct: 61 GNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGT 120
Query: 121 ALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQD 180
ALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQD
Sbjct: 121 ALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQD 180
Query: 181 KRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRN 240
KRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRN
Sbjct: 181 KRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRN 240
Query: 241 HPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPS 300
HPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPS
Sbjct: 241 HPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPS 300
Query: 301 DKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILA 360
DKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILA
Sbjct: 301 DKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILA 360
Query: 361 PGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCN 420
PGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCN
Sbjct: 361 PGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCN 420
Query: 421 TSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQ 480
TSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQ
Sbjct: 421 TSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQ 480
Query: 481 GSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPE 540
GSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPE
Sbjct: 481 GSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPE 540
Query: 541 DQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGS 600
DQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGS
Sbjct: 541 DQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGS 600
Query: 601 YTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERSVRLTWI 660
YTCVASTELDQDLAKAYLTVL GRPDRPRDLELTDLAERSVRLTWI
Sbjct: 601 YTCVASTELDQDLAKAYLTVL---------------GRPDRPRDLELTDLAERSVRLTWI 645
Query: 661 PGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVG 720
PGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVG
Sbjct: 646 PGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVG 705
Query: 721 SSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRR 780
SSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRR
Sbjct: 706 SSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRR 765
Query: 781 RETREAWNNVTVWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDYPRAAP 840
RETREAWNNVTVWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDYPRAAP
Sbjct: 766 RETREAWNNVTVWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDYPRAAP 825
Query: 841 TEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQASFPGD 900
TEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQASFPGD
Sbjct: 826 TEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQASFPGD 885
Query: 901 RLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSETKEFTTPEGVPSAPRRFRVRQPNLETIN 960
RLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSETKEFTTPEGVPSAPRRFRVRQPNLETIN
Sbjct: 886 RLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSETKEFTTPEGVPSAPRRFRVRQPNLETIN 945
Query: 961 LEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSA 1020
LEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSA
Sbjct: 946 LEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSA 1005
Query: 1021 RTQVGSGEAVTEESPAPPNEATPTAAYTNNQADIATQGWFIGLMCAIALLVLILLIVCFI 1080
RTQVGSGEAVTEESPAPPNEATPTAAYTNNQADIATQGWFIGLMCAIALLVLILLIVCFI
Sbjct: 1006 RTQVGSGEAVTEESPAPPNEATPTAAYTNNQADIATQGWFIGLMCAIALLVLILLIVCFI 1065
Query: 1081 KRSRGGKYPVREKKDVPLGPEDPKEEDGSFDYSDEDNKPLQGSQTSLDGTIKQQESDDSL 1140
KRSRGGKYPVREKKDVPLGPEDPKEEDGSFDYSDEDNKPLQGSQTSLDGTIKQQESDDSL
Sbjct: 1066 KRSRGGKYPVREKKDVPLGPEDPKEEDGSFDYSDEDNKPLQGSQTSLDGTIKQQESDDSL 1125
Query: 1141 VDYGEGGEGQFNEDGSFIGQYTVKKDKEETEGNESSEATSPVNAIYSLA 1189
VDYGEGGEGQFNEDGSFIGQYTVKKDKEETEGNESSEATSPVNAIYSLA
Sbjct: 1126 VDYGEGGEGQFNEDGSFIGQYTVKKDKEETEGNESSEATSPVNAIYSLA 1174
>gi|89903008 neurofascin isoform 4 precursor [Homo sapiens]
Length = 1169
Score = 2387 bits (6185), Expect = 0.0
Identities = 1169/1189 (98%), Positives = 1169/1189 (98%), Gaps = 20/1189 (1%)
Query: 1 MARQPPPPWVHAAFLLCLLSLGGAIEIPMDLTQPPTITKQSAKDHIVDPRDNILIECEAK 60
MARQPPPPWVHAAFLLCLLSLGGAIEIPMDLTQPPTITKQSAKDHIVDPRDNILIECEAK
Sbjct: 1 MARQPPPPWVHAAFLLCLLSLGGAIEIPMDLTQPPTITKQSAKDHIVDPRDNILIECEAK 60
Query: 61 GNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGT 120
GNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGT
Sbjct: 61 GNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGT 120
Query: 121 ALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQD 180
ALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQD
Sbjct: 121 ALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQD 180
Query: 181 KRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRN 240
KRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRN
Sbjct: 181 KRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRN 240
Query: 241 HPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPS 300
HPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPS
Sbjct: 241 HPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPS 300
Query: 301 DKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILA 360
DKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILA
Sbjct: 301 DKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILA 360
Query: 361 PGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCN 420
PGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCN
Sbjct: 361 PGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCN 420
Query: 421 TSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQ 480
TSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQ
Sbjct: 421 TSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQ 480
Query: 481 GSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPE 540
GSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPE
Sbjct: 481 GSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPE 540
Query: 541 DQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGS 600
DQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGS
Sbjct: 541 DQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGS 600
Query: 601 YTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERSVRLTWI 660
YTCVASTELDQDLAKAYLTVL GRPDRPRDLELTDLAERSVRLTWI
Sbjct: 601 YTCVASTELDQDLAKAYLTVL---------------GRPDRPRDLELTDLAERSVRLTWI 645
Query: 661 PGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVG 720
PGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVG
Sbjct: 646 PGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVG 705
Query: 721 SSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRR 780
SSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRR
Sbjct: 706 SSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRR 765
Query: 781 RETREAWNNVTVWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDYPRAAP 840
RETREAWNNVTVWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDYPRAAP
Sbjct: 766 RETREAWNNVTVWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDYPRAAP 825
Query: 841 TEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQASFPGD 900
TEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQASFPGD
Sbjct: 826 TEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQASFPGD 885
Query: 901 RLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSETKEFTTPEGVPSAPRRFRVRQPNLETIN 960
RLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSETKEFTTPEGVPSAPRRFRVRQPNLETIN
Sbjct: 886 RLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSETKEFTTPEGVPSAPRRFRVRQPNLETIN 945
Query: 961 LEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSA 1020
LEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSA
Sbjct: 946 LEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSA 1005
Query: 1021 RTQVGSGEAVTEESPAPPNEATPTAAYTNNQADIATQGWFIGLMCAIALLVLILLIVCFI 1080
RTQVGSGEAVTEESPAPPNE AYTNNQADIATQGWFIGLMCAIALLVLILLIVCFI
Sbjct: 1006 RTQVGSGEAVTEESPAPPNE-----AYTNNQADIATQGWFIGLMCAIALLVLILLIVCFI 1060
Query: 1081 KRSRGGKYPVREKKDVPLGPEDPKEEDGSFDYSDEDNKPLQGSQTSLDGTIKQQESDDSL 1140
KRSRGGKYPVREKKDVPLGPEDPKEEDGSFDYSDEDNKPLQGSQTSLDGTIKQQESDDSL
Sbjct: 1061 KRSRGGKYPVREKKDVPLGPEDPKEEDGSFDYSDEDNKPLQGSQTSLDGTIKQQESDDSL 1120
Query: 1141 VDYGEGGEGQFNEDGSFIGQYTVKKDKEETEGNESSEATSPVNAIYSLA 1189
VDYGEGGEGQFNEDGSFIGQYTVKKDKEETEGNESSEATSPVNAIYSLA
Sbjct: 1121 VDYGEGGEGQFNEDGSFIGQYTVKKDKEETEGNESSEATSPVNAIYSLA 1169
>gi|237858675 neurofascin isoform 1 precursor [Homo sapiens]
Length = 1240
Score = 1684 bits (4361), Expect = 0.0
Identities = 844/953 (88%), Positives = 863/953 (90%), Gaps = 34/953 (3%)
Query: 1 MARQPPPPWVHAAFLLCLLSLGGAIEIPMD------LTQPPTITKQSAKDHIVDPRDNIL 54
MARQPPPPWVHAAFLLCLLSLGGAIEIPMD LTQPPTITKQSAKDHIVDPRDNIL
Sbjct: 1 MARQPPPPWVHAAFLLCLLSLGGAIEIPMDPSIQNELTQPPTITKQSAKDHIVDPRDNIL 60
Query: 55 IECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFA 114
IECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFA
Sbjct: 61 IECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFA 120
Query: 115 RNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSM 174
RNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSM
Sbjct: 121 RNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSM 180
Query: 175 EPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYN 234
EPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLT
Sbjct: 181 EPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTT---- 236
Query: 235 DSSLRNHPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKK 294
RGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKK
Sbjct: 237 -------------RGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKK 283
Query: 295 GGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEP 354
GGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEP
Sbjct: 284 GGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEP 343
Query: 355 KNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSR 414
KNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSR
Sbjct: 344 KNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSR 403
Query: 415 AVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLR 474
AVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLR
Sbjct: 404 AVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLR 463
Query: 475 WFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTR 534
WFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTR
Sbjct: 464 WFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTR 523
Query: 535 IYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVA 594
IYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVA
Sbjct: 524 IYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVA 583
Query: 595 ERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERS 654
ERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERS
Sbjct: 584 ERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERS 643
Query: 655 VRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVI 714
VRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVI
Sbjct: 644 VRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVI 703
Query: 715 AINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRY 774
AINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRY
Sbjct: 704 AINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRY 763
Query: 775 IVKWRRRETREAWNNVTVWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGED 834
IVKWRRRETREAWNNVTVWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGED
Sbjct: 764 IVKWRRRETREAWNNVTVWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGED 823
Query: 835 YPRAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQ 894
P +AP +VR N I+L+W+ + + G + Y Y + N K+
Sbjct: 824 LP-SAPRRFRVRQPNLETINLEWD--HPEHPNGIMIGYTLKY-----VAFNGTKVGKQIV 875
Query: 895 ASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSETKEFTTP--EGVPSA 945
+F ++ + V R P S Y+ + G G + T+E P E P+A
Sbjct: 876 ENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSG-EAVTEESPAPPNEATPTA 927
Score = 302 bits (773), Expect = 1e-81
Identities = 162/236 (68%), Positives = 176/236 (74%), Gaps = 15/236 (6%)
Query: 954 PNLETINLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSR 1013
PN + N+ W H P + ++Y+ N TK + P +Q TD
Sbjct: 1020 PNSKWANITWKHNFGPG---TDFVVEYIDSNHTKKTVPVKAQAQP------IQLTDLYPG 1070
Query: 1014 YRFTLSARTQVGSGEAVTEESPAPPNEATPTAAYTNNQADIATQGWFIGLMCAIALLVLI 1073
+TL ++ G + T + + AYTNNQADIATQGWFIGLMCAIALLVLI
Sbjct: 1071 MTYTLRVYSRDNEGISSTVIT------FMTSTAYTNNQADIATQGWFIGLMCAIALLVLI 1124
Query: 1074 LLIVCFIKRSRGGKYPVREKKDVPLGPEDPKEEDGSFDYSDEDNKPLQGSQTSLDGTIKQ 1133
LLIVCFIKRSRGGKYPVREKKDVPLGPEDPKEEDGSFDYSDEDNKPLQGSQTSLDGTIKQ
Sbjct: 1125 LLIVCFIKRSRGGKYPVREKKDVPLGPEDPKEEDGSFDYSDEDNKPLQGSQTSLDGTIKQ 1184
Query: 1134 QESDDSLVDYGEGGEGQFNEDGSFIGQYTVKKDKEETEGNESSEATSPVNAIYSLA 1189
QESDDSLVDYGEGGEGQFNEDGSFIGQYTVKKDKEETEGNESSEATSPVNAIYSLA
Sbjct: 1185 QESDDSLVDYGEGGEGQFNEDGSFIGQYTVKKDKEETEGNESSEATSPVNAIYSLA 1240
Score = 301 bits (771), Expect = 2e-81
Identities = 295/966 (30%), Positives = 434/966 (44%), Gaps = 115/966 (11%)
Query: 126 IRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSS-MEPITQDKRVS 184
I+ ++++ P K++ +V + ++C G P+P W +S I +D RVS
Sbjct: 33 IQNELTQPPTITKQSAKDHIVDPRDNILIECEAK-GNPAPSFHWTRNSRFFNIAKDPRVS 91
Query: 185 -QGHNGDL---YFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRN 240
+ +G L + S ++ + +Y C AR F + N L+V
Sbjct: 92 MRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALS--NRIRLQV------------- 136
Query: 241 HPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIAS-GVPTPDIAWYKKGGD-L 298
+ S ++P+ +V G L L+C G+P+P I W + +
Sbjct: 137 -------------SKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPI 183
Query: 299 PSDKAKFENFNKALRITNVSEED-SGEYFCLASNKMGSIRHTI----------------S 341
DK + N L +NV +D +Y C N HTI +
Sbjct: 184 TQDKRVSQGHNGDLYFSNVMLQDMQTDYSC---NARFHFTHTIQQKNPFTLKVLTTRGVA 240
Query: 342 VRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAG 401
R + Y + ++ G D L C A+G P P + W G L P+ +
Sbjct: 241 ERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDL----PSDKAKFEN 296
Query: 402 DTIIFRDTQISSR--AVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRT 459
R T +S Y C SN+ G + V V P + P+N ++
Sbjct: 297 FNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAP--GEDG 354
Query: 460 RLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEI-KMIRKEDQGIYTCVATNIL 518
RL C G+P PT++W NG+ N + G I + + + +Y C +N
Sbjct: 355 RLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEH 414
Query: 519 GKAENQVRLEVKDPTRIYRMPEDQVAR--RGTTVQLECRVKHDPSLKLTVSWLKDDEPLY 576
G + V D P +Q+ R +L+C P T+ W K+ +
Sbjct: 415 GYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIP--TLRWFKNGQGSN 472
Query: 577 I--GNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAAL 634
+ GN E+ SL I + + DQG YTCVA+ L KA V + PT R+ +
Sbjct: 473 LDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNIL----GKAENQVRLEVKDPT-RIYRM 527
Query: 635 PKGRPDRPR---DLELTDLAERSVRLT--WIPGDANNSPITDYV---VQFEEDQFQPGVW 686
P+ + R LE + S++LT W+ D P+ Y+ ++ E+D ++
Sbjct: 528 PEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDD---EPL--YIGNRMKKEDDSLT--IF 580
Query: 687 HDHSKYPGSVNS-AVLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDV 745
+ GS A L + + + ++ + P+ R P D+
Sbjct: 581 GVAERDQGSYTCVASTELDQDLAKAYLTVLADQ------ATPTNRLAALPKGRPDRPRDL 634
Query: 746 KGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETREA-WNNVTVW-GS-RYVVGQT 802
+ + ++ +TW P +A ++ P Y+V++ + + W++ + + GS V +
Sbjct: 635 ELTDLAERSVRLTWIPGDANNS--PITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRL 692
Query: 803 PVYVPYEIRVQAENDFGKGPE--PESVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWNRV 860
YV Y+ RV A N+ G P SG P + P +VK + + W +
Sbjct: 693 SPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAP-PESNPGDVKGEGTRKNNMEITWTPM 751
Query: 861 YSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLEMV 920
+ + G Y + R + + W + G R VV + Y Y++ +
Sbjct: 752 NATSAFGPNLRYIVKWRRRET--REAW-----NNVTVWGSRY--VVGQTPVYVPYEIRVQ 802
Query: 921 VVNGRGDGPRSETKEFTTPEGVPSAPRRFRVRQPNLETINLEWDHPEHPNGIMIGYTLKY 980
N G GP E+ + E +PSAPRRFRVRQPNLETINLEWDHPEHPNGIMIGYTLKY
Sbjct: 803 AENDFGKGPEPESVIGYSGEDLPSAPRRFRVRQPNLETINLEWDHPEHPNGIMIGYTLKY 862
Query: 981 VAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESPAPPNE 1040
VAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESPAPPNE
Sbjct: 863 VAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESPAPPNE 922
Query: 1041 ATPTAA 1046
ATPTAA
Sbjct: 923 ATPTAA 928
>gi|237858682 neurofascin isoform 6 precursor [Homo sapiens]
Length = 613
Score = 1231 bits (3184), Expect = 0.0
Identities = 603/623 (96%), Positives = 604/623 (96%), Gaps = 17/623 (2%)
Query: 1 MARQPPPPWVHAAFLLCLLSLGGAIEIPMDLTQPPTITKQSAKDHIVDPRDNILIECEAK 60
MARQPPPPWVHAAFLLCLLSLGGAIEIPMDLTQPPTITKQSAKDHIVDPRDNILIECEAK
Sbjct: 1 MARQPPPPWVHAAFLLCLLSLGGAIEIPMDLTQPPTITKQSAKDHIVDPRDNILIECEAK 60
Query: 61 GNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGT 120
GNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGT
Sbjct: 61 GNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGT 120
Query: 121 ALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQD 180
ALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQD
Sbjct: 121 ALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQD 180
Query: 181 KRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRN 240
KRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLT
Sbjct: 181 KRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTT---------- 230
Query: 241 HPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPS 300
RGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPS
Sbjct: 231 -------RGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPS 283
Query: 301 DKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILA 360
DKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILA
Sbjct: 284 DKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILA 343
Query: 361 PGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCN 420
PGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCN
Sbjct: 344 PGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCN 403
Query: 421 TSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQ 480
TSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQ
Sbjct: 404 TSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQ 463
Query: 481 GSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPE 540
GSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPE
Sbjct: 464 GSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPE 523
Query: 541 DQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGS 600
DQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGS
Sbjct: 524 DQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGS 583
Query: 601 YTCVASTELDQDLAKAYLTVLAD 623
YTCVASTELDQDLAKAYLTVL +
Sbjct: 584 YTCVASTELDQDLAKAYLTVLGN 606
>gi|237858680 neurofascin isoform 5 precursor [Homo sapiens]
Length = 619
Score = 1224 bits (3167), Expect = 0.0
Identities = 603/629 (95%), Positives = 604/629 (96%), Gaps = 23/629 (3%)
Query: 1 MARQPPPPWVHAAFLLCLLSLGGAIEIPMD------LTQPPTITKQSAKDHIVDPRDNIL 54
MARQPPPPWVHAAFLLCLLSLGGAIEIPMD LTQPPTITKQSAKDHIVDPRDNIL
Sbjct: 1 MARQPPPPWVHAAFLLCLLSLGGAIEIPMDPSIQNELTQPPTITKQSAKDHIVDPRDNIL 60
Query: 55 IECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFA 114
IECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFA
Sbjct: 61 IECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFA 120
Query: 115 RNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSM 174
RNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSM
Sbjct: 121 RNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSM 180
Query: 175 EPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYN 234
EPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLT
Sbjct: 181 EPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTT---- 236
Query: 235 DSSLRNHPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKK 294
RGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKK
Sbjct: 237 -------------RGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKK 283
Query: 295 GGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEP 354
GGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEP
Sbjct: 284 GGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEP 343
Query: 355 KNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSR 414
KNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSR
Sbjct: 344 KNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSR 403
Query: 415 AVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLR 474
AVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLR
Sbjct: 404 AVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLR 463
Query: 475 WFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTR 534
WFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTR
Sbjct: 464 WFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTR 523
Query: 535 IYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVA 594
IYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVA
Sbjct: 524 IYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVA 583
Query: 595 ERDQGSYTCVASTELDQDLAKAYLTVLAD 623
ERDQGSYTCVASTELDQDLAKAYLTVL +
Sbjct: 584 ERDQGSYTCVASTELDQDLAKAYLTVLGN 612
>gi|81158224 neuronal cell adhesion molecule isoform B precursor [Homo
sapiens]
Length = 1183
Score = 1219 bits (3153), Expect = 0.0
Identities = 607/1182 (51%), Positives = 815/1182 (68%), Gaps = 29/1182 (2%)
Query: 15 LLCLLSLGGAIEIPMDLTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSR 74
+L L + A+E+P+DL QPPTIT+QS KD+I+DPR+NI+I+CEAKG P PSF WTRN
Sbjct: 20 ILFLCQMISALEVPLDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGT 79
Query: 75 FFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSP 134
F+I KDP V+M+ +GTL+I+ S G+ E YEG YQC ARN+ G A+SN I ++ S+SP
Sbjct: 80 HFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSP 139
Query: 135 LWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFS 194
LW KE L+P+ +Q G L L C PP GLP P+IFWM +S + + Q +RVSQG NGDLYFS
Sbjct: 140 LWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFS 199
Query: 195 NVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRNHPD--MYSARGVAE 252
NV+ +D + DY C ARF+ T TIQQK P ++KV++ ND+ N D Y A+ E
Sbjct: 200 NVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRE 259
Query: 253 RTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKAL 312
R P+F+ P+G AS++ LRG L LECIA G+PTP I W K+ G LP ++ ++NF K L
Sbjct: 260 RPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTL 319
Query: 313 RITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRAN 372
+I +VSE DSG Y C+A N +G+I HTISVRVKAAPYW+ P+NL+L+PGEDG L+CRAN
Sbjct: 320 QIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRAN 379
Query: 373 GNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANA 432
GNPKP + W+ NG P++ AP +P+R++ GDTIIF + Q S AVYQCN SNE+GYLLANA
Sbjct: 380 GNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANA 439
Query: 433 FVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVY 492
FV+VL PPR+L+P N L +VI LDC FFGSP+PT+ WFK +GS L Y ++
Sbjct: 440 FVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLH 499
Query: 493 ENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQL 552
ENG+LEI + +K+ G YTCVA N LG A+N+V LE+KDPT I + PE V +RG+ V
Sbjct: 500 ENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSF 559
Query: 553 ECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQD 612
EC+VKHD +L LTV WLKD+ L R + D L + V++ D G+YTCVA+T LD
Sbjct: 560 ECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVADVSDDDSGTYTCVANTTLDSV 619
Query: 613 LAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERSVRLTWIPGDANNSPITDY 672
A A L+V+ P+ P DLELTD ++SV+L+W PGD NNSPIT +
Sbjct: 620 SASAVLSVV---------------DVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKF 664
Query: 673 VVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSERYR 732
++++E+ +PG+WH ++ G+ +A L+LSPYVNY FRV+A+N +G S PS SE+Y
Sbjct: 665 IIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYL 724
Query: 733 TSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETREAWNNVTV 792
T + P+ NP V+G G+ +N+ ITW P+N + GP L+Y V WR+++ + W +V V
Sbjct: 725 TKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSVVV 784
Query: 793 WG-SRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDYPRAAPTEVKVRVMNST 851
S+Y+V TP +VPY I+VQA ND G PEP V+G+SGED P AP V+V V+NST
Sbjct: 785 ANVSKYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNST 844
Query: 852 AISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQASFPGDRLRGVVSRLFP 911
+ W+ V +++G L+ YR YYW+ S K +++ +F G + G++ L P
Sbjct: 845 LAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEP 904
Query: 912 YSNYKLEMVVVNGRGDGPRSETKEFTTPEGVPSAPRRFRVRQPNLETINLEWDHPEHPNG 971
+S+Y L + VVNG+G+GP S + F TPEGVPSAP ++ P L+++ LEWD P HPNG
Sbjct: 905 FSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNG 964
Query: 972 IMIGYTLKYVAFNGT-KVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAV 1030
I+ YTLKY N T ++G + N+T++T++ + +RY+F A+T GSG +
Sbjct: 965 ILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQI 1024
Query: 1031 TEESPAPPNEATPTAAYTNNQADIATQGWFIGLMCAIALLVLILLIVCFIKRSRGGKYPV 1090
TEE+ +E A + Q DIATQGWFIGLMCA+ALL+LILLIVCFI+R++GGKYPV
Sbjct: 1025 TEEAVTTVDE-----AMASRQVDIATQGWFIGLMCAVALLILILLIVCFIRRNKGGKYPV 1079
Query: 1091 REKKDVPLGPE--DPKEEDGSF-DYSD-EDNKPL-QGSQTSLDGTIKQQESDDSLVDYGE 1145
+EK+D PE KE+DG+F +YSD ED+KPL +GS+T D T+K+++SDDSLVDYGE
Sbjct: 1080 KEKEDAHADPEIQPMKEDDGTFGEYSDAEDHKPLKKGSRTPSDRTVKKEDSDDSLVDYGE 1139
Query: 1146 GGEGQFNEDGSFIGQYTVKKDKEETEGNESSEATSPVNAIYS 1187
G GQFNEDGSFIGQY+ KK+KE EGNESSEA SPVNA+ S
Sbjct: 1140 GVNGQFNEDGSFIGQYSGKKEKEPAEGNESSEAPSPVNAMNS 1181
>gi|81158226 neuronal cell adhesion molecule isoform A precursor [Homo
sapiens]
Length = 1304
Score = 1037 bits (2681), Expect = 0.0
Identities = 511/1037 (49%), Positives = 698/1037 (67%), Gaps = 15/1037 (1%)
Query: 15 LLCLLSLGGAIEIPMD------LTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFH 68
+L L + A+E+P+D L QPPTIT+QS KD+I+DPR+NI+I+CEAKG P PSF
Sbjct: 20 ILFLCQMISALEVPLDPKLLEDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFS 79
Query: 69 WTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRL 128
WTRN F+I KDP V+M+ +GTL+I+ S G+ E YEG YQC ARN+ G A+SN I +
Sbjct: 80 WTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVV 139
Query: 129 QVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHN 188
+ S+SPLW KE L+P+ +Q G L L C PP GLP P+IFWM +S + + Q +RVSQG N
Sbjct: 140 RPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLN 199
Query: 189 GDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRNHPD--MYS 246
GDLYFSNV+ +D + DY C ARF+ T TIQQK P ++KV++ ND+ N D Y
Sbjct: 200 GDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYG 259
Query: 247 ARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFE 306
A+ ER P+F+ P+G AS++ LRG L LECIA G+PTP I W K+ G LP ++ ++
Sbjct: 260 AKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYK 319
Query: 307 NFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGR 366
NF K L+I +VSE DSG Y C+A N +G+I HTISVRVKAAPYW+ P+NL+L+PGEDG
Sbjct: 320 NFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGT 379
Query: 367 LVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHG 426
L+CRANGNPKP + W+ NG P++ AP +P+R++ GDTIIF + Q S AVYQCN SNE+G
Sbjct: 380 LICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYG 439
Query: 427 YLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDG 486
YLLANAFV+VL PPR+L+P N L +VI LDC FFGSP+PT+ WFK +GS L
Sbjct: 440 YLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHE 499
Query: 487 GNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARR 546
Y ++ENG+LEI + +K+ G YTCVA N LG A+N+V LE+KDPT I + PE V +R
Sbjct: 500 DIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQR 559
Query: 547 GTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCVAS 606
G+ V EC+VKHD +L LTV WLKD+ L R + D L + V++ D G+YTCVA+
Sbjct: 560 GSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVADVSDDDSGTYTCVAN 619
Query: 607 TELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERSVRLTWIPGDANN 666
T LD A A L+V+A TP A P+ P DLELTD ++SV+L+W PGD NN
Sbjct: 620 TTLDSVSASAVLSVVAPTPTP-----APVYDVPNPPFDLELTDQLDKSVQLSWTPGDDNN 674
Query: 667 SPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSL 726
SPIT +++++E+ +PG+WH ++ G+ +A L+LSPYVNY FRV+A+N +G S PS
Sbjct: 675 SPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSE 734
Query: 727 PSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETREA 786
SE+Y T + P+ NP V+G G+ +N+ ITW P+N + GP L+Y V WR+++ +
Sbjct: 735 ASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDE 794
Query: 787 WNNVTVWG-SRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDYPRAAPTEVKV 845
W +V V S+Y+V TP +VPY I+VQA ND G PEP V+G+SGED P AP V+V
Sbjct: 795 WTSVVVANVSKYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRV 854
Query: 846 RVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQASFPGDRLRGV 905
V+NST + W+ V +++G L+ YR YYW+ S K +++ +F G + G+
Sbjct: 855 NVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGM 914
Query: 906 VSRLFPYSNYKLEMVVVNGRGDGPRSETKEFTTPEGVPSAPRRFRVRQPNLETINLEWDH 965
+ L P+S+Y L + VVNG+G+GP S + F TPEGVPSAP ++ P L+++ LEWD
Sbjct: 915 LPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDP 974
Query: 966 PEHPNGIMIGYTLKYVAFNGT-KVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQV 1024
P HPNGI+ YTLKY N T ++G + N+T++T++ + +RY+F A+T
Sbjct: 975 PSHPNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSA 1034
Query: 1025 GSGEAVTEESPAPPNEA 1041
GSG +TEE+ +EA
Sbjct: 1035 GSGSQITEEAVTTVDEA 1051
Score = 283 bits (724), Expect = 7e-76
Identities = 338/1258 (26%), Positives = 522/1258 (41%), Gaps = 199/1258 (15%)
Query: 32 TQPPTITKQSAKDHIVDPRDNILIECEAK-GNPAPSFHWTRNSRFFNIAKDPRVSMRRRS 90
++ P TK+ + + ++++ C G P P W NS F + + RVS + +
Sbjct: 142 SRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNS-FQRLPQSERVS-QGLN 199
Query: 91 GTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQV-------------------- 130
G L + S PE+ +Y C+AR + + + V
Sbjct: 200 GDL---YFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTE 256
Query: 131 ---SKSP-------LWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQD 180
+KS L P+ N G L+L+C GLP+P+I+W + ++
Sbjct: 257 FYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAE-GLPTPIIYWAKED-GMLPKN 314
Query: 181 KRVSQGHNGDLYFSNVMLQDMQTDYSC---NARFHFTHTIQQKNPFTLKVLTNHPYNDSS 237
+ V + L +V D +Y C NA HTI +
Sbjct: 315 RTVYKNFEKTLQIIHVSEAD-SGNYQCIAKNALGAIHHTISVR----------------- 356
Query: 238 LRNHPDMYSARGVAERTPSFMYPQGTASSQMVLR-GMDLLLECIASGVPTPDIAWYKKGG 296
+ P ++ TA +VL G D L C A+G P P I+W G
Sbjct: 357 -------------VKAAPYWI----TAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGV 399
Query: 297 DL---PSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDE 353
+ P D ++ + + + +NV E S Y C ASN+ G + V V A P +
Sbjct: 400 PIEIAPDDPSRKIDGDTII-FSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILT 458
Query: 354 PKNLI--LAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQI 411
P N + + L C G+P PT++W G + + T+ Q
Sbjct: 459 PANTLYQVIANRPALLDCAFFGSPLPTIEWF-KGAKGSALHEDIYVLHENGTLEIPVAQK 517
Query: 412 SSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIP 471
S Y C N+ G + + D P + + + V + +C
Sbjct: 518 DSTGTYTCVARNKLGMAKNEVHLEIKD--PTWIVKQPEYAVVQRGSMVSFECKVKHDHTL 575
Query: 472 TLR--WFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEV 529
+L W K+ + L + L + + +D G YTCVA L L V
Sbjct: 576 SLTVLWLKDNR--ELPSDERFTVDKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSV 633
Query: 530 KDPTR----IYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLK-DDEPLYIGNRMKKE 584
PT +Y +P LE + D S++L SW DD I + +
Sbjct: 634 VAPTPTPAPVYDVPNPPF-------DLELTDQLDKSVQL--SWTPGDDNNSPITKFIIEY 684
Query: 585 DDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRD 644
+D++ G+ T V+ T Q A+ L+ + + + ++ K P +
Sbjct: 685 EDAMHKPGLWHHQ----TEVSGT---QTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASE 737
Query: 645 LELTDLAER---------------SVRLTWIP--GDANNSPITDYVVQFEE----DQFQP 683
LT +E ++ +TW P G +N P Y V + + D++
Sbjct: 738 QYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTS 797
Query: 684 GVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAP-PESNP 742
V + SKY V +V Y +V A+N++G + P+ SG P P
Sbjct: 798 VVVANVSKY------IVSGTPTFVPYLIKVQALNDMGFAPE--PAVVMGHSGEDLPMVAP 849
Query: 743 GDVKGEGTRKNNMEITWTPMNATSAFGPNLRY-IVKWR-----RRETREAWNNVTVWGSR 796
G+V+ E+ W P+ S G Y I W+ +R R + +
Sbjct: 850 GNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGS 909
Query: 797 YVVGQTPVYVP---YEIRVQAENDFGKGPEPESVIGYSGEDYPRAAPTEVKVRVMNSTAI 853
G P P Y + V+ N G+GP + + E P +AP+ +K+ ++
Sbjct: 910 KTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVP-SAPSSLKIVNPTLDSL 968
Query: 854 SLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQASFPGDRLRGVVSRLFPYS 913
+L+W+ G L EY Y +S + P ++ R + L +
Sbjct: 969 TLEWDP--PSHPNGILTEYTLKYQPINSTHE----LGPLVDLKIPANKTRWTLKNLNFST 1022
Query: 914 NYKLEMVVVNGRGDGPRSETKEFTTPEGVPSAPR-----RFRVRQPNLETI--------- 959
YK G G + + TT + P + + P + +
Sbjct: 1023 RYKFYFYAQTSAGSGSQITEEAVTTVDEAGILPPDVGAGKVQAVNPRISNLTAAAAETYA 1082
Query: 960 NLEWDH--PEHPNGIMIGYTLKY-VAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRF 1016
N+ W++ PEH N + ++Y VA + + K+IV +++ F ++ P + Y+
Sbjct: 1083 NISWEYEGPEHVN-----FYVEYGVAGSKEEWRKEIVNG---SRSFFGLKGLMPGTAYKV 1134
Query: 1017 TLSARTQVG--SGEAVTEESPAPPNEATPTAAYTNNQADIATQGWFIGLMCAIALLVLIL 1074
+ A G S E V E PA + Q DIATQGWFIGLMCA+ALL+LIL
Sbjct: 1135 RVGAVGDSGFVSSEDVFETGPA----------MASRQVDIATQGWFIGLMCAVALLILIL 1184
Query: 1075 LIVCFIKRSRGGKYPVREKKDVPLGPE--DPKEEDGSF-DYSD-EDNKPLQ-GSQTSLDG 1129
LIVCFI+R++GGKYPV+EK+D PE KE+DG+F +YSD ED+KPL+ GS+T D
Sbjct: 1185 LIVCFIRRNKGGKYPVKEKEDAHADPEIQPMKEDDGTFGEYSDAEDHKPLKKGSRTPSDR 1244
Query: 1130 TIKQQESDDSLVDYGEGGEGQFNEDGSFIGQYTVKKDKEETEGNESSEATSPVNAIYS 1187
T+K+++SDDSLVDYGEG GQFNEDGSFIGQY+ KK+KE EGNESSEA SPVNA+ S
Sbjct: 1245 TVKKEDSDDSLVDYGEGVNGQFNEDGSFIGQYSGKKEKEPAEGNESSEAPSPVNAMNS 1302
>gi|27894376 cell adhesion molecule with homology to L1CAM precursor
[Homo sapiens]
Length = 1224
Score = 819 bits (2115), Expect = 0.0
Identities = 478/1236 (38%), Positives = 661/1236 (53%), Gaps = 92/1236 (7%)
Query: 15 LLCLLSLGGAIEIPMDLTQPPTITKQSAKDHIVDPRDNIL-IECEAKGNPAPSFHWTRNS 73
+ LL AIEIP + Q PTI KQS K + P D IECEAKGNP P+F WT++
Sbjct: 15 MFLLLKFSKAIEIPSSVQQVPTIIKQS-KVQVAFPFDEYFQIECEAKGNPEPTFSWTKDG 73
Query: 74 RFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKS 133
F D R+ SGT I + G ++G+Y+CFA NK G A+S I V
Sbjct: 74 NPFYFT-DHRIIPSNNSGTFRIP--NEGHISHFQGKYRCFASNKLGIAMSEEIEFIVPSV 130
Query: 134 PLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYF 193
P +PKE +DP+ V+EG P+ L CNPP GLP I+WM+ +E I QD+RV GDLYF
Sbjct: 131 PKFPKEKIDPLEVEEGDPIVLPCNPPKGLPPLHIYWMNIELEHIEQDERVYMSQKGDLYF 190
Query: 194 SNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRNHPDMYSARGVAER 253
+NV +D + DY C A F TI QK P L V + NDSS A + +R
Sbjct: 191 ANVEEKDSRNDYCCFAAFPRLRTIVQKMPMKLTVNSLKHANDSSSSTEIGS-KANSIKQR 249
Query: 254 TPSFMYP---QGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNK 310
P + P G+ SS +L+G LLLEC A G+PTP + W K GGDLP + EN+ K
Sbjct: 250 KPKLLLPPTESGSESSITILKGEILLLECFAEGLPTPQVDWNKIGGDLPKGRETKENYGK 309
Query: 311 ALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCR 370
L+I NVS +D G Y C ASN +G+ H V V+ P W +P++ + + G +G L+C
Sbjct: 310 TLKIENVSYQDKGNYRCTASNFLGTATHDFHVIVEEPPRWTKKPQSAVYSTGSNGILLCE 369
Query: 371 ANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTII-----FRDTQISSRAVYQCNTSNEH 425
A G P+PT++W VNG P+ + P AGD + F + Q + AVYQC SN H
Sbjct: 370 AEGEPQPTIKWRVNGSPVDNHP------FAGDVVFPREISFTNLQPNHTAVYQCEASNVH 423
Query: 426 GYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLD 485
G +LANA + V+DV P + + + ++ L C FF SP + W K + L+
Sbjct: 424 GTILANANIDVVDVRPLIQTKDGENYATVVGYSAFLHCEFFASPEAVVSWQKVEEVKPLE 483
Query: 486 GGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVAR 545
G YH+YENG+L+I +ED G Y+C N +GK L++++ T++ P++
Sbjct: 484 GRRYHIYENGTLQINRTTEEDAGSYSCWVENAIGKTAVTANLDIRNATKLRVSPKNPRIP 543
Query: 546 RGTTVQLECRVKHDPSLK--LTVSWLKDDEPLYIGN----RMKKEDDSLTIFGVAERDQG 599
+ ++L C K D LK L +SW KD E I R+ + +LTI V DQG
Sbjct: 544 KLHMLELHCESKCDSHLKHSLKLSWSKDGEAFEINGTEDGRIIIDGANLTISNVTLEDQG 603
Query: 600 SYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERSVRLTW 659
Y C A T LD +TVL PD P +L L++ RSVRLTW
Sbjct: 604 IYCCSAHTALDSAADITQVTVL---------------DVPDPPENLHLSERQNRSVRLTW 648
Query: 660 IPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEV 719
G +NS I++Y+V+FE ++ +PG W + ++ G + +L L+P+V YQFRVIA+NEV
Sbjct: 649 EAGADHNSNISEYIVEFEGNKEEPGRWEELTRVQGKKTTVILPLAPFVRYQFRVIAVNEV 708
Query: 720 GSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWR 779
G S PS PS+ + T A P+ NP +++ + ++ M I W P+ + GP L Y V W+
Sbjct: 709 GRSQPSQPSDHHETPPAAPDRNPQNIRVQASQPKEMIIKWEPLKSMEQNGPGLEYRVTWK 768
Query: 780 RRETREAWNNVTVWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDYPRAA 839
+ W TV V VY PY+++VQA N G GP+P+SV YSGEDYP A
Sbjct: 769 PQGAPVEWEEETVTNHTLRVMTPAVYAPYDVKVQAINQLGSGPDPQSVTLYSGEDYPDTA 828
Query: 840 PTEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQASFPG 899
P V V+NST + + W+ V D V G+L+ Y+ +W+ SLL ++ F G
Sbjct: 829 PVIHGVDVINSTLVKVTWSTVPKDRVHGRLKGYQINWWKTKSLLDGRTHPKEVNILRFSG 888
Query: 900 DRLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSETKEFTTPEGVPSAPRRFRVRQPNLETI 959
R G+V L +S + L ++ N +G GP SE F TPEGVP P +V + + +T
Sbjct: 889 QRNSGMVPSLDAFSEFHLTVLAYNSKGAGPESEPYIFQTPEGVPEQPTFLKVIKVDKDTA 948
Query: 960 NLEWDHPEHPNGIMIGYTLKYVAFNGT-KVGK-QIVENFSPNQTKFTVQRTDPVSRYRFT 1017
L W P+ NG + GY L+Y N T ++G+ + +P++ + + + ++Y+F
Sbjct: 949 TLSWGLPKKLNGNLTGYLLQYQIINDTYEIGELNDINITTPSKPSWHLSNLNATTKYKFY 1008
Query: 1018 LSARTQVGSGEAVTEESPA---------------------PPNEATPTA----------- 1045
L A T G G+ +TEES P P A
Sbjct: 1009 LRACTSQGCGKPITEESSTLGEGSKGIGKISGVNLTQKTHPIEVFEPGAEHIVRLMTKNW 1068
Query: 1046 ----------------AYTNNQADIATQGWFIGLMCAIALLVLILLIVCFIKRSRGGKYP 1089
Y DI+TQGWFIGLMCAIALL L+LL VCF+KR+RGGKY
Sbjct: 1069 GDNDSIFQDVIETRGREYAGLYDDISTQGWFIGLMCAIALLTLLLLTVCFVKRNRGGKYS 1128
Query: 1090 VREKKDVPLGPEDPKEEDGSF-DYSDEDNKPLQGSQTSLDGTIKQQESDDSLVDYGEGGE 1148
V+EK+D+ PE +D +F +YSD D KPL+GS SL+ ++ ES DSLV+YGEG
Sbjct: 1129 VKEKEDLHPDPEIQSVKDETFGEYSDSDEKPLKGSLRSLNRDMQPTESADSLVEYGEGDH 1188
Query: 1149 GQFNEDGSFIGQYTVKKDKEETEGNESSEATSPVNA 1184
G F+EDGSFIG Y K+K E N SS AT P+ A
Sbjct: 1189 GLFSEDGSFIGAYAGSKEKGSVESNGSSTATFPLRA 1224
>gi|221316760 L1 cell adhesion molecule isoform 3 precursor [Homo
sapiens]
Length = 1248
Score = 723 bits (1867), Expect = 0.0
Identities = 393/1022 (38%), Positives = 556/1022 (54%), Gaps = 40/1022 (3%)
Query: 17 CLLSLGGAIEIPMDLTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFF 76
CLL I+IP +L +PP IT+QS + +V P D+I ++CEA G P F WTR+ F
Sbjct: 17 CLL-----IQIPEELMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHF 71
Query: 77 NIAKDPRVSMRR--RSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSP 134
++ V++ + SG+ I + + ++G Y+CFA NK GTA+S+ IRL +P
Sbjct: 72 KPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAP 131
Query: 135 LWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFS 194
WPKE + PV V+EG + L CNPPP I+WM+S + I QD+RV+ G NG+LYF+
Sbjct: 132 KWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYFA 191
Query: 195 NVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRNHPDMYSARGVAERT 254
NV+ D +DY C+A F T TI QK P L+V + + +R
Sbjct: 192 NVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATN-----------------SMIDRK 234
Query: 255 PSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRI 314
P ++P ++S + L+G L+LECIA G PTP I W + G +P+D+ ++N NK L++
Sbjct: 235 PRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQL 294
Query: 315 TNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGN 374
V EED GEY CLA N +GS RH V V+AAPYWL +P++ + PGE RL C+ G
Sbjct: 295 LKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGR 354
Query: 375 PKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFV 434
P+P V W +NG P++ + + +I + Q S V QC N HG LLANA++
Sbjct: 355 PQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYI 414
Query: 435 SVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYEN 494
V+ +P ++L+ NQ + + L C FG+P+P+++W + L + Y N
Sbjct: 415 YVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYAN 474
Query: 495 GSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLEC 554
G+L I+ ++ D G Y C+A N L+VKD T+I + P + ++G+ V C
Sbjct: 475 GTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTC 534
Query: 555 RVKHDPSLKLTVSWLKDDEPLY-IGNRMKK--EDDSLTIFGVAERDQGSYTCVASTELDQ 611
+ DPSL+ +++W D L +G+ K ED L I + DQG+Y+CVASTELD
Sbjct: 535 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDV 594
Query: 612 DLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERSVRLTWIPGDANNSPITD 671
++A L V+ P RL DL L L + VR++W P + +N+PI
Sbjct: 595 VESRAQLLVVGSPG-PVPRLVL---------SDLHL--LTQSQVRVSWSPAEDHNAPIEK 642
Query: 672 YVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSERY 731
Y ++FE+ + P W+ K PG+ S L+LSPYV+Y FRV AIN+ G PS SE
Sbjct: 643 YDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETV 702
Query: 732 RTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETREAWNNVT 791
T A PE NP DVKGEG NM ITW P+ P ++Y V+WR + TR W
Sbjct: 703 VTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQI 762
Query: 792 VWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDYPRAAPTEVKVRVMNST 851
V VV T +VPYEI+VQA N GKGPEP+ IGYSGEDYP+A P + ++NS+
Sbjct: 763 VSDPFLVVSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSS 822
Query: 852 AISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQASFPGDRLRGVVSRLFP 911
A+ ++W V V+G LR Y YWRE S K+ + P + ++S L P
Sbjct: 823 AVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRP 882
Query: 912 YSNYKLEMVVVNGRGDGPRSETKEFTTPEGVPSAPRRFRVRQPNLETINLEWDHPEHPNG 971
YS+Y LE+ NGRG GP SE F+TPEGVP P + + ++ L W P NG
Sbjct: 883 YSSYHLEVQAFNGRGSGPASEF-TFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNG 941
Query: 972 IMIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVT 1031
++ GY L Y + G+ P + P RYRF L A T+ G GEA+
Sbjct: 942 VLTGYVLSYHPLDEGGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIV 1001
Query: 1032 EE 1033
E
Sbjct: 1002 RE 1003
Score = 241 bits (615), Expect = 3e-63
Identities = 302/1202 (25%), Positives = 477/1202 (39%), Gaps = 115/1202 (9%)
Query: 26 EIPMDLTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVS 85
EI + P K++ K V+ +++++ C + P + NS+ +I +D RV+
Sbjct: 122 EIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVT 181
Query: 86 MRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNR----IRLQVSKSP------- 134
M + + + + +Y C A + + +R++ + S
Sbjct: 182 MGQNGNLYFANVLTS----DNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL 237
Query: 135 LWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFS 194
L+P + +V +G PL L+C G P+P I W+ S P+ D+ Q HN L
Sbjct: 238 LFPTNSSSHLVALQGQPLVLECIAE-GFPTPTIKWLRPS-GPMPADRVTYQNHNKTLQLL 295
Query: 195 NVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRNHPDMYSARGVAERT 254
V +D +Y C A ++SL + Y E
Sbjct: 296 KVGEED-DGEYRCLA-------------------------ENSLGSARHAYYV--TVEAA 327
Query: 255 PSFMY-PQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKG---GDLPSDKAKFENFNK 310
P +++ PQ S + G L+C G P P++ W G +L D+ K+
Sbjct: 328 PYWLHKPQ----SHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQ-KYRIQRG 382
Query: 311 ALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKN--LILAPGEDGRLV 368
AL ++NV D+ C A N+ G + + V P + N + G L+
Sbjct: 383 ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQTYMAVQGSTAYLL 442
Query: 369 CRANGNPKPTVQWMVNGEP--LQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHG 426
C+A G P P+VQW+ LQ P A T+ RD Q + Y C +N+
Sbjct: 443 CKAFGAPVPSVQWLDEDGTTVLQDERFFP---YANGTLGIRDLQANDTGRYFCLAANDQN 499
Query: 427 YLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQG-SNLD 485
+ A + V D PR+ + + F S P++ W +G+ L
Sbjct: 500 NVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELG 559
Query: 486 GGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRL-EVKDPTRIYRMPEDQVA 544
+ + E+G L I + DQG Y+CVA+ L E++ +L V P + R+ +
Sbjct: 560 DSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLH 619
Query: 545 RRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCV 604
Q + RV P+ K D ++ SL G +Q S T
Sbjct: 620 ---LLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSL---GKVPGNQTSTTLK 673
Query: 605 ASTELDQDLAKAYLTVLAD-QATPTNRLAALPKGRPDR-PRDLELTDLAERSVRLTWIPG 662
S + + + +P + P+ P++ P D++ ++ +TW P
Sbjct: 674 LSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPL 733
Query: 663 DAN--NSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVG 720
N+P Y VQ+ Q G W + + V S +V Y+ +V A+N G
Sbjct: 734 RWMDWNAPQVQYRVQWRP-QGTRGPWQE--QIVSDPFLVVSNTSTFVPYEIKVQAVNSQG 790
Query: 721 SSHPSLPSERYRTSGAP-PESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWR 779
P SG P++ P E + + + W P++ G Y V +
Sbjct: 791 KGPE--PQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYW 848
Query: 780 RRETREAWNNVTVWGSRYVV----------GQTPVYVPYEIRVQAENDFGKGPEPESVIG 829
R ++ + + VV G P Y Y + VQA N G+G P S
Sbjct: 849 REGSQRKHSKRHIHKDHVVVPANTTSVILSGLRP-YSSYHLEVQAFN--GRGSGPASEFT 905
Query: 830 YSGEDYPRAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVS 889
+S + P + + ++T++ L+W S G L Y Y K
Sbjct: 906 FSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHN--GVLTGYVLSYHPLDEGGKGQLSF 963
Query: 890 QKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSETKEFTTP-EGVPSAPRR 948
R P R + L P+ Y+ ++ G G + T G+
Sbjct: 964 NLRD----PELRTHNLTD-LSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDFGNI 1018
Query: 949 FRVRQPNLETINLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVENF-SPNQTKFTVQR 1007
N ++ W E + + + A K G + + S NQ+ +T
Sbjct: 1019 SATAGENYSVVS--WVPKEGQCNFR--FHILFKALGEEKGGASLSPQYVSYNQSSYTQWD 1074
Query: 1008 TDPVSRYRFTLSARTQVGSGEAVTEESPAPPNEATPTAAYTNNQADIATQGWFIGLMCAI 1067
P + Y L AV + T A AT+GWFIG + AI
Sbjct: 1075 LQPDTDYEIHLFKERMFRHQMAV---------KTNGTGRVRLPPAGFATEGWFIGFVSAI 1125
Query: 1068 ALLVLILLIVCFIKRSRGGKYPVREKKDVPLGPEDPKEEDGSF-DYSDEDNKPLQGSQTS 1126
LL+L+LLI+CFIKRS+GGKY V++K+D + E +D +F +YSD + K SQ S
Sbjct: 1126 ILLLLVLLILCFIKRSKGGKYSVKDKEDTQVDSEARPMKDETFGEYSDNEEKAFGSSQPS 1185
Query: 1127 LDGTIKQQESDDSLVDYGEGGEGQFNEDGSFIGQYTVKKDKEETEGNESSEATSPVNAIY 1186
L+G IK SDDSL DYG + QFNEDGSFIGQY+ KK+KE GN+SS ATSP+N
Sbjct: 1186 LNGDIKPLGSDDSLADYGGSVDVQFNEDGSFIGQYSGKKEKEAAGGNDSSGATSPINPAV 1245
Query: 1187 SL 1188
+L
Sbjct: 1246 AL 1247
>gi|13435353 L1 cell adhesion molecule isoform 2 precursor [Homo
sapiens]
Length = 1253
Score = 716 bits (1848), Expect = 0.0
Identities = 392/1027 (38%), Positives = 556/1027 (54%), Gaps = 45/1027 (4%)
Query: 17 CLLSLGGAIEIPMD-----LTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTR 71
CLL I+IP + + +PP IT+QS + +V P D+I ++CEA G P F WTR
Sbjct: 17 CLL-----IQIPEEYEGHHVMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTR 71
Query: 72 NSRFFNIAKDPRVSMRR--RSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQ 129
+ F ++ V++ + SG+ I + + ++G Y+CFA NK GTA+S+ IRL
Sbjct: 72 DGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLM 131
Query: 130 VSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNG 189
+P WPKE + PV V+EG + L CNPPP I+WM+S + I QD+RV+ G NG
Sbjct: 132 AEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNG 191
Query: 190 DLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRNHPDMYSARG 249
+LYF+NV+ D +DY C+A F T TI QK P L+V +
Sbjct: 192 NLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATN-----------------S 234
Query: 250 VAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFN 309
+ +R P ++P ++S + L+G L+LECIA G PTP I W + G +P+D+ ++N N
Sbjct: 235 MIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN 294
Query: 310 KALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVC 369
K L++ V EED GEY CLA N +GS RH V V+AAPYWL +P++ + PGE RL C
Sbjct: 295 KTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDC 354
Query: 370 RANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLL 429
+ G P+P V W +NG P++ + + +I + Q S V QC N HG LL
Sbjct: 355 QVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLL 414
Query: 430 ANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNY 489
ANA++ V+ +P ++L+ NQ + + L C FG+P+P+++W + L +
Sbjct: 415 ANAYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERF 474
Query: 490 HVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTT 549
Y NG+L I+ ++ D G Y C+A N L+VKD T+I + P + ++G+
Sbjct: 475 FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSR 534
Query: 550 VQLECRVKHDPSLKLTVSWLKDDEPLY-IGNRMKK--EDDSLTIFGVAERDQGSYTCVAS 606
V C+ DPSL+ +++W D L +G+ K ED L I + DQG+Y+CVAS
Sbjct: 535 VTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVAS 594
Query: 607 TELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERSVRLTWIPGDANN 666
TELD ++A L V+ P RL DL L L + VR++W P + +N
Sbjct: 595 TELDVVESRAQLLVVGSPG-PVPRLVL---------SDLHL--LTQSQVRVSWSPAEDHN 642
Query: 667 SPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSL 726
+PI Y ++FE+ + P W+ K PG+ S L+LSPYV+Y FRV AIN+ G PS
Sbjct: 643 APIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSP 702
Query: 727 PSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETREA 786
SE T A PE NP DVKGEG NM ITW P+ P ++Y V+WR + TR
Sbjct: 703 VSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGP 762
Query: 787 WNNVTVWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDYPRAAPTEVKVR 846
W V VV T +VPYEI+VQA N GKGPEP+ IGYSGEDYP+A P +
Sbjct: 763 WQEQIVSDPFLVVSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIE 822
Query: 847 VMNSTAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQASFPGDRLRGVV 906
++NS+A+ ++W V V+G LR Y YWRE S K+ + P + ++
Sbjct: 823 ILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVIL 882
Query: 907 SRLFPYSNYKLEMVVVNGRGDGPRSETKEFTTPEGVPSAPRRFRVRQPNLETINLEWDHP 966
S L PYS+Y LE+ NGRG GP SE F+TPEGVP P + + ++ L W P
Sbjct: 883 SGLRPYSSYHLEVQAFNGRGSGPASEF-TFSTPEGVPGHPEALHLECQSNTSLLLRWQPP 941
Query: 967 EHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGS 1026
NG++ GY L Y + G+ P + P RYRF L A T+ G
Sbjct: 942 LSHNGVLTGYVLSYHPLDEGGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGP 1001
Query: 1027 GEAVTEE 1033
GEA+ E
Sbjct: 1002 GEAIVRE 1008
Score = 241 bits (615), Expect = 3e-63
Identities = 302/1202 (25%), Positives = 477/1202 (39%), Gaps = 115/1202 (9%)
Query: 26 EIPMDLTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVS 85
EI + P K++ K V+ +++++ C + P + NS+ +I +D RV+
Sbjct: 127 EIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVT 186
Query: 86 MRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNR----IRLQVSKSP------- 134
M + + + + +Y C A + + +R++ + S
Sbjct: 187 MGQNGNLYFANVLTS----DNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL 242
Query: 135 LWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFS 194
L+P + +V +G PL L+C G P+P I W+ S P+ D+ Q HN L
Sbjct: 243 LFPTNSSSHLVALQGQPLVLECIAE-GFPTPTIKWLRPS-GPMPADRVTYQNHNKTLQLL 300
Query: 195 NVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRNHPDMYSARGVAERT 254
V +D +Y C A ++SL + Y E
Sbjct: 301 KVGEED-DGEYRCLA-------------------------ENSLGSARHAYYV--TVEAA 332
Query: 255 PSFMY-PQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKG---GDLPSDKAKFENFNK 310
P +++ PQ S + G L+C G P P++ W G +L D+ K+
Sbjct: 333 PYWLHKPQ----SHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQ-KYRIQRG 387
Query: 311 ALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKN--LILAPGEDGRLV 368
AL ++NV D+ C A N+ G + + V P + N + G L+
Sbjct: 388 ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQTYMAVQGSTAYLL 447
Query: 369 CRANGNPKPTVQWMVNGEP--LQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHG 426
C+A G P P+VQW+ LQ P A T+ RD Q + Y C +N+
Sbjct: 448 CKAFGAPVPSVQWLDEDGTTVLQDERFFP---YANGTLGIRDLQANDTGRYFCLAANDQN 504
Query: 427 YLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQG-SNLD 485
+ A + V D PR+ + + F S P++ W +G+ L
Sbjct: 505 NVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELG 564
Query: 486 GGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRL-EVKDPTRIYRMPEDQVA 544
+ + E+G L I + DQG Y+CVA+ L E++ +L V P + R+ +
Sbjct: 565 DSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLH 624
Query: 545 RRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCV 604
Q + RV P+ K D ++ SL G +Q S T
Sbjct: 625 ---LLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSL---GKVPGNQTSTTLK 678
Query: 605 ASTELDQDLAKAYLTVLAD-QATPTNRLAALPKGRPDR-PRDLELTDLAERSVRLTWIPG 662
S + + + +P + P+ P++ P D++ ++ +TW P
Sbjct: 679 LSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPL 738
Query: 663 DAN--NSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVG 720
N+P Y VQ+ Q G W + + V S +V Y+ +V A+N G
Sbjct: 739 RWMDWNAPQVQYRVQWRP-QGTRGPWQE--QIVSDPFLVVSNTSTFVPYEIKVQAVNSQG 795
Query: 721 SSHPSLPSERYRTSGAP-PESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWR 779
P SG P++ P E + + + W P++ G Y V +
Sbjct: 796 KGPE--PQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYW 853
Query: 780 RRETREAWNNVTVWGSRYVV----------GQTPVYVPYEIRVQAENDFGKGPEPESVIG 829
R ++ + + VV G P Y Y + VQA N G+G P S
Sbjct: 854 REGSQRKHSKRHIHKDHVVVPANTTSVILSGLRP-YSSYHLEVQAFN--GRGSGPASEFT 910
Query: 830 YSGEDYPRAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVS 889
+S + P + + ++T++ L+W S G L Y Y K
Sbjct: 911 FSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHN--GVLTGYVLSYHPLDEGGKGQLSF 968
Query: 890 QKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSETKEFTTP-EGVPSAPRR 948
R P R + L P+ Y+ ++ G G + T G+
Sbjct: 969 NLRD----PELRTHNLTD-LSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDFGNI 1023
Query: 949 FRVRQPNLETINLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVENF-SPNQTKFTVQR 1007
N ++ W E + + + A K G + + S NQ+ +T
Sbjct: 1024 SATAGENYSVVS--WVPKEGQCNFR--FHILFKALGEEKGGASLSPQYVSYNQSSYTQWD 1079
Query: 1008 TDPVSRYRFTLSARTQVGSGEAVTEESPAPPNEATPTAAYTNNQADIATQGWFIGLMCAI 1067
P + Y L AV + T A AT+GWFIG + AI
Sbjct: 1080 LQPDTDYEIHLFKERMFRHQMAV---------KTNGTGRVRLPPAGFATEGWFIGFVSAI 1130
Query: 1068 ALLVLILLIVCFIKRSRGGKYPVREKKDVPLGPEDPKEEDGSF-DYSDEDNKPLQGSQTS 1126
LL+L+LLI+CFIKRS+GGKY V++K+D + E +D +F +YSD + K SQ S
Sbjct: 1131 ILLLLVLLILCFIKRSKGGKYSVKDKEDTQVDSEARPMKDETFGEYSDNEEKAFGSSQPS 1190
Query: 1127 LDGTIKQQESDDSLVDYGEGGEGQFNEDGSFIGQYTVKKDKEETEGNESSEATSPVNAIY 1186
L+G IK SDDSL DYG + QFNEDGSFIGQY+ KK+KE GN+SS ATSP+N
Sbjct: 1191 LNGDIKPLGSDDSLADYGGSVDVQFNEDGSFIGQYSGKKEKEAAGGNDSSGATSPINPAV 1250
Query: 1187 SL 1188
+L
Sbjct: 1251 AL 1252
>gi|4557707 L1 cell adhesion molecule isoform 1 precursor [Homo
sapiens]
Length = 1257
Score = 716 bits (1848), Expect = 0.0
Identities = 392/1027 (38%), Positives = 556/1027 (54%), Gaps = 45/1027 (4%)
Query: 17 CLLSLGGAIEIPMD-----LTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTR 71
CLL I+IP + + +PP IT+QS + +V P D+I ++CEA G P F WTR
Sbjct: 17 CLL-----IQIPEEYEGHHVMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTR 71
Query: 72 NSRFFNIAKDPRVSMRR--RSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQ 129
+ F ++ V++ + SG+ I + + ++G Y+CFA NK GTA+S+ IRL
Sbjct: 72 DGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLM 131
Query: 130 VSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNG 189
+P WPKE + PV V+EG + L CNPPP I+WM+S + I QD+RV+ G NG
Sbjct: 132 AEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNG 191
Query: 190 DLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRNHPDMYSARG 249
+LYF+NV+ D +DY C+A F T TI QK P L+V +
Sbjct: 192 NLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATN-----------------S 234
Query: 250 VAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFN 309
+ +R P ++P ++S + L+G L+LECIA G PTP I W + G +P+D+ ++N N
Sbjct: 235 MIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN 294
Query: 310 KALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVC 369
K L++ V EED GEY CLA N +GS RH V V+AAPYWL +P++ + PGE RL C
Sbjct: 295 KTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDC 354
Query: 370 RANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLL 429
+ G P+P V W +NG P++ + + +I + Q S V QC N HG LL
Sbjct: 355 QVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLL 414
Query: 430 ANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNY 489
ANA++ V+ +P ++L+ NQ + + L C FG+P+P+++W + L +
Sbjct: 415 ANAYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERF 474
Query: 490 HVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTT 549
Y NG+L I+ ++ D G Y C+A N L+VKD T+I + P + ++G+
Sbjct: 475 FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSR 534
Query: 550 VQLECRVKHDPSLKLTVSWLKDDEPLY-IGNRMKK--EDDSLTIFGVAERDQGSYTCVAS 606
V C+ DPSL+ +++W D L +G+ K ED L I + DQG+Y+CVAS
Sbjct: 535 VTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVAS 594
Query: 607 TELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERSVRLTWIPGDANN 666
TELD ++A L V+ P RL DL L L + VR++W P + +N
Sbjct: 595 TELDVVESRAQLLVVGSPG-PVPRLVL---------SDLHL--LTQSQVRVSWSPAEDHN 642
Query: 667 SPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSL 726
+PI Y ++FE+ + P W+ K PG+ S L+LSPYV+Y FRV AIN+ G PS
Sbjct: 643 APIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSP 702
Query: 727 PSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETREA 786
SE T A PE NP DVKGEG NM ITW P+ P ++Y V+WR + TR
Sbjct: 703 VSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGP 762
Query: 787 WNNVTVWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDYPRAAPTEVKVR 846
W V VV T +VPYEI+VQA N GKGPEP+ IGYSGEDYP+A P +
Sbjct: 763 WQEQIVSDPFLVVSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIE 822
Query: 847 VMNSTAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQASFPGDRLRGVV 906
++NS+A+ ++W V V+G LR Y YWRE S K+ + P + ++
Sbjct: 823 ILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVIL 882
Query: 907 SRLFPYSNYKLEMVVVNGRGDGPRSETKEFTTPEGVPSAPRRFRVRQPNLETINLEWDHP 966
S L PYS+Y LE+ NGRG GP SE F+TPEGVP P + + ++ L W P
Sbjct: 883 SGLRPYSSYHLEVQAFNGRGSGPASEF-TFSTPEGVPGHPEALHLECQSNTSLLLRWQPP 941
Query: 967 EHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGS 1026
NG++ GY L Y + G+ P + P RYRF L A T+ G
Sbjct: 942 LSHNGVLTGYVLSYHPLDEGGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGP 1001
Query: 1027 GEAVTEE 1033
GEA+ E
Sbjct: 1002 GEAIVRE 1008
Score = 235 bits (600), Expect = 2e-61
Identities = 302/1206 (25%), Positives = 477/1206 (39%), Gaps = 119/1206 (9%)
Query: 26 EIPMDLTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVS 85
EI + P K++ K V+ +++++ C + P + NS+ +I +D RV+
Sbjct: 127 EIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVT 186
Query: 86 MRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNR----IRLQVSKSP------- 134
M + + + + +Y C A + + +R++ + S
Sbjct: 187 MGQNGNLYFANVLTS----DNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL 242
Query: 135 LWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFS 194
L+P + +V +G PL L+C G P+P I W+ S P+ D+ Q HN L
Sbjct: 243 LFPTNSSSHLVALQGQPLVLECIAE-GFPTPTIKWLRPS-GPMPADRVTYQNHNKTLQLL 300
Query: 195 NVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRNHPDMYSARGVAERT 254
V +D +Y C A ++SL + Y E
Sbjct: 301 KVGEED-DGEYRCLA-------------------------ENSLGSARHAYYV--TVEAA 332
Query: 255 PSFMY-PQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKG---GDLPSDKAKFENFNK 310
P +++ PQ S + G L+C G P P++ W G +L D+ K+
Sbjct: 333 PYWLHKPQ----SHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQ-KYRIQRG 387
Query: 311 ALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKN--LILAPGEDGRLV 368
AL ++NV D+ C A N+ G + + V P + N + G L+
Sbjct: 388 ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQTYMAVQGSTAYLL 447
Query: 369 CRANGNPKPTVQWMVNGEP--LQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHG 426
C+A G P P+VQW+ LQ P A T+ RD Q + Y C +N+
Sbjct: 448 CKAFGAPVPSVQWLDEDGTTVLQDERFFP---YANGTLGIRDLQANDTGRYFCLAANDQN 504
Query: 427 YLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQG-SNLD 485
+ A + V D PR+ + + F S P++ W +G+ L
Sbjct: 505 NVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELG 564
Query: 486 GGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRL-EVKDPTRIYRMPEDQVA 544
+ + E+G L I + DQG Y+CVA+ L E++ +L V P + R+ +
Sbjct: 565 DSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLH 624
Query: 545 RRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCV 604
Q + RV P+ K D ++ SL G +Q S T
Sbjct: 625 ---LLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSL---GKVPGNQTSTTLK 678
Query: 605 ASTELDQDLAKAYLTVLAD-QATPTNRLAALPKGRPDR-PRDLELTDLAERSVRLTWIPG 662
S + + + +P + P+ P++ P D++ ++ +TW P
Sbjct: 679 LSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPL 738
Query: 663 DAN--NSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVG 720
N+P Y VQ+ Q G W + + V S +V Y+ +V A+N G
Sbjct: 739 RWMDWNAPQVQYRVQWRP-QGTRGPWQE--QIVSDPFLVVSNTSTFVPYEIKVQAVNSQG 795
Query: 721 SSHPSLPSERYRTSGAP-PESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWR 779
P SG P++ P E + + + W P++ G Y V +
Sbjct: 796 KGPE--PQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYW 853
Query: 780 RRETREAWNNVTVWGSRYVV----------GQTPVYVPYEIRVQAENDFGKGPEPESVIG 829
R ++ + + VV G P Y Y + VQA N G+G P S
Sbjct: 854 REGSQRKHSKRHIHKDHVVVPANTTSVILSGLRP-YSSYHLEVQAFN--GRGSGPASEFT 910
Query: 830 YSGEDYPRAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVS 889
+S + P + + ++T++ L+W S G L Y Y K
Sbjct: 911 FSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHN--GVLTGYVLSYHPLDEGGKGQLSF 968
Query: 890 QKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSETKEFTTP-EGVPSAPRR 948
R P R + L P+ Y+ ++ G G + T G+
Sbjct: 969 NLRD----PELRTHNLTD-LSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDFGNI 1023
Query: 949 FRVRQPNLETINLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVENF-SPNQTKFTVQR 1007
N ++ W E + + + A K G + + S NQ+ +T
Sbjct: 1024 SATAGENYSVVS--WVPKEGQCNFR--FHILFKALGEEKGGASLSPQYVSYNQSSYTQWD 1079
Query: 1008 TDPVSRYRFTLSARTQVGSGEAVTEESPAPPNEATPTAAYTNNQADIATQGWFIGLMCAI 1067
P + Y L AV + T A AT+GWFIG + AI
Sbjct: 1080 LQPDTDYEIHLFKERMFRHQMAV---------KTNGTGRVRLPPAGFATEGWFIGFVSAI 1130
Query: 1068 ALLVLILLIVCFIKRSRGGKYPVREKKDVPLGPEDPKEEDGSF-DY----SDEDNKPLQG 1122
LL+L+LLI+CFIKRS+GGKY V++K+D + E +D +F +Y SD + K
Sbjct: 1131 ILLLLVLLILCFIKRSKGGKYSVKDKEDTQVDSEARPMKDETFGEYRSLESDNEEKAFGS 1190
Query: 1123 SQTSLDGTIKQQESDDSLVDYGEGGEGQFNEDGSFIGQYTVKKDKEETEGNESSEATSPV 1182
SQ SL+G IK SDDSL DYG + QFNEDGSFIGQY+ KK+KE GN+SS ATSP+
Sbjct: 1191 SQPSLNGDIKPLGSDDSLADYGGSVDVQFNEDGSFIGQYSGKKEKEAAGGNDSSGATSPI 1250
Query: 1183 NAIYSL 1188
N +L
Sbjct: 1251 NPAVAL 1256
>gi|28373129 contactin 5 isoform short [Homo sapiens]
Length = 1026
Score = 361 bits (926), Expect = 3e-99
Identities = 286/1003 (28%), Positives = 438/1003 (43%), Gaps = 99/1003 (9%)
Query: 9 WVHAAFLLCLLSLGGAIEIPMDLTQPPTITKQSAKDHIVDPRDN----ILIECEAKGNPA 64
W FL + L +++ Q P D I+ P D+ + + CE +GNP
Sbjct: 5 WKLMLFLSVTMCLSESVDYGPVFVQEP--------DDIIFPTDSDEKKVALNCEVRGNPV 56
Query: 65 PSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSN 124
PS+ W RN ++ D R S+ GT +I S + G YQC A N G+ LS
Sbjct: 57 PSYRWLRNGTEIDLESDYRYSLI--DGTFIISNPSEAKDS---GHYQCLATNTVGSILSR 111
Query: 125 RIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEP-ITQDKR- 182
LQ + + V V+EG + L C+PPP P + W+ + + +D R
Sbjct: 112 EATLQFAYLGNFSGRTRSAVSVREGQGVVLMCSPPPHSPEIIYSWVFNEFPSFVAEDSRR 171
Query: 183 -VSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRNH 241
+SQ G+LY S V D+ + Y C + T+ +VL+ P +LRN
Sbjct: 172 FISQ-ETGNLYISKVQTSDVGS-YICLVKNTVTNA---------RVLS--PPTPLTLRND 218
Query: 242 PDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSD 301
M G E +P ++ +G + +EC A G P P I W K G +PS
Sbjct: 219 GVM----GEYEPKIEVHFPFTVTAA----KGTTVKMECFALGNPVPTITWMKVNGYIPS- 269
Query: 302 KAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAP 361
KA+ L I NV +D+G Y C A N G ++V P+W+++ + L
Sbjct: 270 KARLRKSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYTYPHWVEKLNDTQLDS 329
Query: 362 GEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNT 421
G R C+A G P+PT +W+ NG PL P E+ ++ + S +YQC
Sbjct: 330 GSPLRWECKATGKPRPTYRWLKNGVPLS---PQSRVEMVNGVLMIHNVNQSDAGMYQCLA 386
Query: 422 SNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTR---LDCPFFGSPIPTLRWFKN 478
N++G + A+A + +L P NQL + I+ + + ++C GSP PT+ W K
Sbjct: 387 ENKYGAIYASAELKILASAPTFAL--NQLKKTIIVTKDQEVVIECKPQGSPKPTISW-KK 443
Query: 479 GQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRM 538
G + + + +GSL I K D+G Y C N+ G AE L VK+PTRI
Sbjct: 444 GDRAVRENKRIAILPDGSLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKEPTRIELT 503
Query: 539 PEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPL--------YIGNRMKKEDDSLTI 590
P+ G ++ L C+ HD SL +T W +P+ + R + L I
Sbjct: 504 PKRTELTVGESIVLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQASSADLMI 563
Query: 591 FGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDL 650
+ G Y C T D +A L V +G P P + + ++
Sbjct: 564 RNILLMHAGRYGCRVQTTADSVSDEAELLV---------------RGPPGPPGIVIVEEI 608
Query: 651 AERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYP----GSVNSAV-LRLSP 705
E + L+W P N+SPI+ Y +Q F G W P G + SA+ + L+P
Sbjct: 609 TESTATLSWSPAADNHSPISSYNLQ-ARSPFSLG-WQTVKTVPEIITGDMESAMAVDLNP 666
Query: 706 YVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNAT 765
+V Y+FRV+A N +G+ PS PS RT+ A P++ P +V G R++ + I W P++
Sbjct: 667 WVEYEFRVVATNPIGTGDPSTPSRMIRTNEAVPKTAPTNVSGRSGRRHELVIAWEPVSEE 726
Query: 766 SAFGPNLRYIVKWRRRETREAWNNVTVWGSR-----YVVGQTPVYVPYEIRVQAENDFGK 820
G YIV +R TR W V S Y P P+E++V N+ G
Sbjct: 727 FQNGEGFGYIVAFRPNGTR-GWKEKMVTSSEASKFIYRDESVPPLTPFEVKVGVYNNKGD 785
Query: 821 GPEPESVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRES 880
GP + V+ S E P AAPT+VK ++ + I + W + G+ + + YW++
Sbjct: 786 GPFSQIVVICSAEGEPSAAPTDVKATSVSVSEILVAWKHIKESL--GRPQGFEVGYWKDM 843
Query: 881 SLLKNLWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSETKEFTTPE 940
+ R SF +++ L + Y + NG G GP S TT +
Sbjct: 844 EQEDTAETVKTRGNESFV------ILTGLEGNTLYHFTVRAYNGAGYGPPSSEVSATTKK 897
Query: 941 GVPS-APRRFRVRQPNLETINLEWDH--PEHPNGIMIGYTLKY 980
PS AP R Q + ++L W+ P ++GY + Y
Sbjct: 898 SPPSQAPSNLRWEQQGSQ-VSLGWEPVIPLANESEVVGYKVFY 939
Score = 31.2 bits (69), Expect = 6.1
Identities = 27/111 (24%), Positives = 42/111 (37%), Gaps = 2/111 (1%)
Query: 941 GVPSAPRRFRVRQPNLETINLEWDHPEHPNGIMIGYTLKYVA-FN-GTKVGKQIVENFSP 998
G P P V + T L W + + Y L+ + F+ G + K + E +
Sbjct: 595 GPPGPPGIVIVEEITESTATLSWSPAADNHSPISSYNLQARSPFSLGWQTVKTVPEIITG 654
Query: 999 NQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESPAPPNEATPTAAYTN 1049
+ +P Y F + A +G+G+ T NEA P A TN
Sbjct: 655 DMESAMAVDLNPWVEYEFRVVATNPIGTGDPSTPSRMIRTNEAVPKTAPTN 705
>gi|7657359 contactin 5 isoform long [Homo sapiens]
Length = 1100
Score = 360 bits (923), Expect = 6e-99
Identities = 280/968 (28%), Positives = 428/968 (44%), Gaps = 91/968 (9%)
Query: 44 DHIVDPRDN----ILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRS 99
D I+ P D+ + + CE +GNP PS+ W RN ++ D R S+ GT +I S
Sbjct: 106 DDIIFPTDSDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLI--DGTFIISNPS 163
Query: 100 GGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPP 159
+ G YQC A N G+ LS LQ + + V V+EG + L C+PP
Sbjct: 164 EAKDS---GHYQCLATNTVGSILSREATLQFAYLGNFSGRTRSAVSVREGQGVVLMCSPP 220
Query: 160 PGLPSPVIFWMSSSMEP-ITQDKR--VSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHT 216
P P + W+ + + +D R +SQ G+LY S V D+ + Y C + T+
Sbjct: 221 PHSPEIIYSWVFNEFPSFVAEDSRRFISQ-ETGNLYISKVQTSDVGS-YICLVKNTVTNA 278
Query: 217 IQQKNPFTLKVLTNHPYNDSSLRNHPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLL 276
+VL+ P +LRN M G E +P ++ +G +
Sbjct: 279 ---------RVLS--PPTPLTLRNDGVM----GEYEPKIEVHFPFTVTAA----KGTTVK 319
Query: 277 LECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSI 336
+EC A G P P I W K G +PS KA+ L I NV +D+G Y C A N G
Sbjct: 320 MECFALGNPVPTITWMKVNGYIPS-KARLRKSQAVLEIPNVQLDDAGIYECRAENSRGKN 378
Query: 337 RHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPN 396
++V P+W+++ + L G R C+A G P+PT +W+ NG PL P
Sbjct: 379 SFRGQLQVYTYPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLS---PQSR 435
Query: 397 REVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILY 456
E+ ++ + S +YQC N++G + A+A + +L P NQL + I+
Sbjct: 436 VEMVNGVLMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFAL--NQLKKTIIV 493
Query: 457 NRTR---LDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCV 513
+ + ++C GSP PT+ W K G + + + +GSL I K D+G Y C
Sbjct: 494 TKDQEVVIECKPQGSPKPTISW-KKGDRAVRENKRIAILPDGSLRILNASKSDEGKYVCR 552
Query: 514 ATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDE 573
N+ G AE L VK+PTRI P+ G ++ L C+ HD SL +T W +
Sbjct: 553 GENVFGSAEIIASLSVKEPTRIELTPKRTELTVGESIVLNCKAIHDASLDVTFYWTLKGQ 612
Query: 574 PL--------YIGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLADQA 625
P+ + R + L I + G Y C T D +A L V
Sbjct: 613 PIDFEEEGGHFESIRAQASSADLMIRNILLMHAGRYGCRVQTTADSVSDEAELLV----- 667
Query: 626 TPTNRLAALPKGRPDRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGV 685
+G P P + + ++ E + L+W P N+SPI+ Y +Q F G
Sbjct: 668 ----------RGPPGPPGIVIVEEITESTATLSWSPAADNHSPISSYNLQ-ARSPFSLG- 715
Query: 686 WHDHSKYP----GSVNSAV-LRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPES 740
W P G + SA+ + L+P+V Y+FRV+A N +G+ PS PS RT+ A P++
Sbjct: 716 WQTVKTVPEIITGDMESAMAVDLNPWVEYEFRVVATNPIGTGDPSTPSRMIRTNEAVPKT 775
Query: 741 NPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETREAWNNVTVWGSR---- 796
P +V G R++ + I W P++ G YIV +R TR W V S
Sbjct: 776 APTNVSGRSGRRHELVIAWEPVSEEFQNGEGFGYIVAFRPNGTR-GWKEKMVTSSEASKF 834
Query: 797 -YVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDYPRAAPTEVKVRVMNSTAISL 855
Y P P+E++V N+ G GP + V+ S E P AAPT+VK ++ + I +
Sbjct: 835 IYRDESVPPLTPFEVKVGVYNNKGDGPFSQIVVICSAEGEPSAAPTDVKATSVSVSEILV 894
Query: 856 QWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQASFPGDRLRGVVSRLFPYSNY 915
W + G+ + + YW++ + R SF +++ L + Y
Sbjct: 895 AWKHIKESL--GRPQGFEVGYWKDMEQEDTAETVKTRGNESFV------ILTGLEGNTLY 946
Query: 916 KLEMVVVNGRGDGPRSETKEFTTPEGVPS-APRRFRVRQPNLETINLEWDH--PEHPNGI 972
+ NG G GP S TT + PS AP R Q + ++L W+ P
Sbjct: 947 HFTVRAYNGAGYGPPSSEVSATTKKSPPSQAPSNLRWEQQGSQ-VSLGWEPVIPLANESE 1005
Query: 973 MIGYTLKY 980
++GY + Y
Sbjct: 1006 VVGYKVFY 1013
Score = 58.5 bits (140), Expect = 4e-08
Identities = 65/321 (20%), Positives = 121/321 (37%), Gaps = 55/321 (17%)
Query: 40 QSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRS 99
+ D +D + EC+A G P P++ W +N + P+ + +G L+I
Sbjct: 394 EKLNDTQLDSGSPLRWECKATGKPRPTYRWLKN----GVPLSPQSRVEMVNGVLMIH--- 446
Query: 100 GGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENL-DPVVVQEGAPLTLQCNP 158
+ G YQC A NK+G ++ ++ +P + L ++V + + ++C
Sbjct: 447 -NVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIECK- 504
Query: 159 PPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQ 218
P G P P I W + ++KR++ +G L N D + Y C F
Sbjct: 505 PQGSPKPTISWKKGD-RAVRENKRIAILPDGSLRILNASKSD-EGKYVCRGENVF----- 557
Query: 219 QKNPFTLKVLTNHPYNDSSLRNHPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLE 278
++ ++ V E T + P+ T + G ++L
Sbjct: 558 ---------------------GSAEIIASLSVKEPTRIELTPKRTE----LTVGESIVLN 592
Query: 279 CIASGVPTPDIAWY-----------KKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFC 327
C A + D+ +Y ++GG S +A+ + + L I N+ +G Y C
Sbjct: 593 CKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQASSAD--LMIRNILLMHAGRYGC 650
Query: 328 LASNKMGSIRHTISVRVKAAP 348
S+ + V+ P
Sbjct: 651 RVQTTADSVSDEAELLVRGPP 671
Score = 43.9 bits (102), Expect = 0.001
Identities = 38/178 (21%), Positives = 76/178 (42%), Gaps = 21/178 (11%)
Query: 31 LTQPPTITKQSAKDHIVDPRDN-ILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRR 89
L PT K I+ +D ++IEC+ +G+P P+ W + R + ++ R+++
Sbjct: 476 LASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWKKGDR--AVRENKRIAILPD 533
Query: 90 SGTLVIDFRSGGRPEEYEGEYQCFARNKFGTA--LSNRIRLQVSKSPLWPKENLDPVVVQ 147
+++ + EG+Y C N FG+A +++ + ++ L PK +
Sbjct: 534 GSLRILN-----ASKSDEGKYVCRGENVFGSAEIIASLSVKEPTRIELTPKR----TELT 584
Query: 148 EGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKR-------VSQGHNGDLYFSNVML 198
G + L C V F+ + +PI ++ +Q + DL N++L
Sbjct: 585 VGESIVLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQASSADLMIRNILL 642
Score = 31.2 bits (69), Expect = 6.1
Identities = 27/111 (24%), Positives = 42/111 (37%), Gaps = 2/111 (1%)
Query: 941 GVPSAPRRFRVRQPNLETINLEWDHPEHPNGIMIGYTLKYVA-FN-GTKVGKQIVENFSP 998
G P P V + T L W + + Y L+ + F+ G + K + E +
Sbjct: 669 GPPGPPGIVIVEEITESTATLSWSPAADNHSPISSYNLQARSPFSLGWQTVKTVPEIITG 728
Query: 999 NQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESPAPPNEATPTAAYTN 1049
+ +P Y F + A +G+G+ T NEA P A TN
Sbjct: 729 DMESAMAVDLNPWVEYEFRVVATNPIGTGDPSTPSRMIRTNEAVPKTAPTN 779
>gi|28373122 contactin 4 isoform a precursor [Homo sapiens]
Length = 1026
Score = 357 bits (916), Expect = 4e-98
Identities = 283/986 (28%), Positives = 434/986 (44%), Gaps = 96/986 (9%)
Query: 8 PW---VHAAFLLCLLSLGGAIEIPMDLTQPPTITKQSAKDHIVDPRDNILIECEAKGNPA 64
PW V +F+LCL + P+ + +P + + + + CE KGNP
Sbjct: 4 PWELLVLQSFILCLAD-DSTLHGPIFIQEPSPVMFPLDSEE-----KKVKLNCEVKGNPK 57
Query: 65 PSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSN 124
P W N + D R S+ G+L+I+ + G YQC A N FGT +S
Sbjct: 58 PHIRWKLNGTDVDTGMDFRYSVVE--GSLLIN---NPNKTQDAGTYQCTATNSFGTIVSR 112
Query: 125 RIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVS 184
+LQ + + V V+ G + L C PPP W+ + ++R
Sbjct: 113 EAKLQFAYLDNFKTRTRSTVSVRRGQGMVLLCGPPPHSGELSYAWIFNEYPSYQDNRRFV 172
Query: 185 QGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNH----PYNDSSLRN 240
G+LY + V D+ +Y+C T+T+ TNH P LRN
Sbjct: 173 SQETGNLYIAKVEKSDVG-NYTCVV----TNTV-----------TNHKVLGPPTPLILRN 216
Query: 241 HPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPS 300
M G E +P+ ++ +G + LEC A G P P I W + G +
Sbjct: 217 DGVM----GEYEPKIEVQFPETVPTA----KGATVKLECFALGNPVPTIIWRRADGKPIA 268
Query: 301 DKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILA 360
KA+ N L I N +ED+G Y C+A N G + A P W+ + ++ +A
Sbjct: 269 RKARRHKSNGILEIPNFQQEDAGLYECVAENSRGKNVARGQLTFYAQPNWIQKINDIHVA 328
Query: 361 PGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCN 420
E+ C+ANG PKPT +W+ NGEPL + ++ T+ +S +YQC
Sbjct: 329 MEENVFWECKANGRPKPTYKWLKNGEPLLT---RDRIQIEQGTLNITIVNLSDAGMYQCL 385
Query: 421 TSNEHGYLLANAFVSVLDVPP---RMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFK 477
N+HG + +NA +SV+ V P R L R L++V ++C SP P W K
Sbjct: 386 AENKHGVIFSNAELSVIAVGPDFSRTLLKRVTLVKV--GGEVVIECKPKASPKPVYTW-K 442
Query: 478 NGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYR 537
G+ + + E+G+L I + K D G YTC+ATN G A + L VKDPTR+
Sbjct: 443 KGRDILKENERITISEDGNLRIINVTKSDAGSYTCIATNHFGTASSTGNLVVKDPTRVMV 502
Query: 538 MPEDQVARRGTTVQLECRVKHDPSLKLTVSW------LKDDEPLYIGNRMKKEDDS--LT 589
P G ++ L C+V HD SL + +W + D R+ +D + L
Sbjct: 503 PPSSMDVTVGESIVLPCQVTHDHSLDIVFTWSFNGHLIDFDRDGDHFERVGGQDSAGDLM 562
Query: 590 IFGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTD 649
I + + G Y C+ T +D+ A A L V +G P P + + +
Sbjct: 563 IRNIQLKHAGKYVCMVQTSVDRLSAAADLIV---------------RGPPGPPEAVTIDE 607
Query: 650 LAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVN-----SAVLRLS 704
+ + + +L+W PG N+SPIT YV+Q F G W S P ++ + V+ L+
Sbjct: 608 ITDTTAQLSWRPGPDNHSPITMYVIQ-ARTPFSVG-WQAVSTVPELIDGKTFTATVVGLN 665
Query: 705 PYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNA 764
P+V Y+FR +A N +G PS PSE+ RT A PE P +V G G K+ + ITW +
Sbjct: 666 PWVEYEFRTVAANVIGIGEPSRPSEKRRTEEALPEVTPANVSGGGGSKSELVITWETVPE 725
Query: 765 TSAFGPNLRYIVKWRRRETREAWNNVTVW----GSRYVVGQTPV--YVPYEIRVQAENDF 818
G Y+V + R + W +TV SRYV V + P+E++V N+
Sbjct: 726 ELQNGRGFGYVVAF-RPYGKMIW-MLTVLASADASRYVFRNESVHPFSPFEVKVGVFNNK 783
Query: 819 GKGPEPESVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWR 878
G+GP + + YS E+ P P + R +++T I + W +G+++ Y YWR
Sbjct: 784 GEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWASPLEKN-RGRIQGYEVKYWR 842
Query: 879 ESSLLKNLWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSETKEFTT 938
+N ++ G++ ++ L Y L + N G GP S T TT
Sbjct: 843 HEDKEEN------ARKIRTVGNQTSTKITNLKGSVLYHLAVKAYNSAGTGPSSATVNVTT 896
Query: 939 PEGVPSAPRRFRVRQPNLETINLEWD 964
+ PS P + + I L WD
Sbjct: 897 RKPPPSQPPGNIIWNSSDSKIILNWD 922
>gi|4827022 contactin 2 precursor [Homo sapiens]
Length = 1040
Score = 357 bits (915), Expect = 5e-98
Identities = 276/955 (28%), Positives = 420/955 (43%), Gaps = 83/955 (8%)
Query: 51 DNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEY 110
+ +L+ C A+ +P ++ W N + +P + G LVI + G Y
Sbjct: 55 EQVLLACRARASPPATYRWKMNGTEMKL--EPGSRHQLVGGNLVI---MNPTKAQDAGVY 109
Query: 111 QCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWM 170
QC A N GT +S L+ + KE DPV EG + L CNPP P W+
Sbjct: 110 QCLASNPVGTVVSREAILRFGFLQEFSKEERDPVKAHEGWGVMLPCNPPAHYPGLSYRWL 169
Query: 171 SSSMEPI--TQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVL 228
+ T + G+LY + D+ +YSC A H + K+ F+
Sbjct: 170 LNEFPNFIPTDGRHFVSQTTGNLYIARTNASDLG-NYSCLATSHMDFST--KSVFSKFAQ 226
Query: 229 TNHPYNDSSLRNHPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPD 288
N D+ L A + R P+ Y L G + LEC A G P P
Sbjct: 227 LNLAAEDTRL-------FAPSIKARFPAETY---------ALVGQQVTLECFAFGNPVPR 270
Query: 289 IAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVR--VKA 346
I W K G L ++ L+I +VS ED G Y C A N G R T+ R V+A
Sbjct: 271 IKWRKVDGSL---SPQWTTAEPTLQIPSVSFEDEGTYECEAENSKG--RDTVQGRIIVQA 325
Query: 347 APYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIF 406
P WL + G + R C A G P+PTV+W+ NGEPL S N +AGD + F
Sbjct: 326 QPEWLKVISDTEADIGSNLRWGCAAAGKPRPTVRWLRNGEPLASQ--NRVEVLAGD-LRF 382
Query: 407 RDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRM-LSPRNQLIRVILYNRTRLDCPF 465
+ +YQC N+HG + A+A ++V + P L+P +LI + C
Sbjct: 383 SKLSLEDSGMYQCVAENKHGTIYASAELAVQALAPDFRLNPVRRLIPAARGGEILIPCQP 442
Query: 466 FGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQV 525
+P + W K G ++ V +G+L I+ I + D+G YTC A N +GKA +
Sbjct: 443 RAAPKAVVLWSK-GTEILVNSSRVTVTPDGTLIIRNISRSDEGKYTCFAENFMGKANSTG 501
Query: 526 RLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPL--------YI 577
L V+D T+I P G + L+C HDP++ LT +W DD P+ Y
Sbjct: 502 ILSVRDATKITLAPSSADINLGDNLTLQCHASHDPTMDLTFTWTLDDFPIDFDKPGGHYR 561
Query: 578 GNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKG 637
+K+ LTI R G YTC+A T +D + + L +G
Sbjct: 562 RTNVKETIGDLTILNAQLRHGGKYTCMAQTVVD---------------SASKEATVLVRG 606
Query: 638 RPDRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSV- 696
P P + + D+ + +++L+W G N+SPI Y +Q G W P ++
Sbjct: 607 PPGPPGGVVVRDIGDTTIQLSWSRGFDNHSPIAKYTLQARTP--PAGKWKQVRTNPANIE 664
Query: 697 ----NSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRK 752
+ VL L+P+++Y+FRVIA N +G+ PS PS + RT A P P + G G
Sbjct: 665 GNAETAQVLGLTPWMDYEFRVIASNILGTGEPSGPSSKIRTREAAPSVAPSGLSGGGGAP 724
Query: 753 NNMEITWTPMNATSAFGPNLRYIVKWRRRETREAWNNVTVWGS---RYVVGQTPV--YVP 807
+ + WTPM+ G Y++ +RR+ + W V G+ +V V Y P
Sbjct: 725 GELIVNWTPMSREYQNGDGFGYLLSFRRQGSTH-WQTARVPGADAQYFVYSNESVRPYTP 783
Query: 808 YEIRVQAENDFGKGPEPESVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWNRVYSDTVQG 867
+E+++++ N G GPE + + YS E+ PR APT+V + ++S+ +++ W V D + G
Sbjct: 784 FEVKIRSYNRRGDGPESLTALVYSAEEEPRVAPTKVWAKGVSSSEMNVTWEPVQQD-MNG 842
Query: 868 QLREYRAYYWRESSLLKNLWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGD 927
L Y YW+ K + R R VS L P + Y + + N G
Sbjct: 843 ILLGYEIRYWKAGD--KEAAADRVRTAGLDTSAR----VSGLHPNTKYHVTVRAYNRAGT 896
Query: 928 GPRSETKEFTTPEGVPSAPRRFRVRQPNLETINLEWDH--PEHPNGIMIGYTLKY 980
GP S + TT + P P + +++++WD P + GY + Y
Sbjct: 897 GPASPSANATTMKPPPRRPPGNISWTFSSSSLSIKWDPVVPFRNESAVTGYKMLY 951
Score = 67.4 bits (163), Expect = 8e-11
Identities = 88/354 (24%), Positives = 124/354 (35%), Gaps = 76/354 (21%)
Query: 44 DHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRP 103
D D N+ C A G P P+ W RN +P S + R L D R
Sbjct: 335 DTEADIGSNLRWGCAAAGKPRPTVRWLRNG-------EPLAS-QNRVEVLAGDLRFSKLS 386
Query: 104 EEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPV----VVQEGAPLTLQCNPP 159
E G YQC A NK GT ++ +++ L P L+PV G + + C P
Sbjct: 387 LEDSGMYQCVAENKHGTIYAS---AELAVQALAPDFRLNPVRRLIPAARGGEILIPCQ-P 442
Query: 160 PGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQ 219
P V+ W S E + RV+ +G L N+ D + Y+C A
Sbjct: 443 RAAPKAVVLW-SKGTEILVNSSRVTVTPDGTLIIRNISRSD-EGKYTCFAE--------- 491
Query: 220 KNPFTLKVLTNHPYNDSSLRNHPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLEC 279
N N + S R + T + SS + G +L L+C
Sbjct: 492 --------------NFMGKANSTGILSVRDATKITLA-------PSSADINLGDNLTLQC 530
Query: 280 IASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSE------------EDSGEYFC 327
AS PT D+ + D P D F+ R TNV E G+Y C
Sbjct: 531 HASHDPTMDLTFTWTLDDFPID---FDKPGGHYRRTNVKETIGDLTILNAQLRHGGKYTC 587
Query: 328 LASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQW 381
+A + S +V V+ PG G +V R G+ + W
Sbjct: 588 MAQTVVDSASKEATVLVRG-------------PPGPPGGVVVRDIGDTTIQLSW 628
>gi|28373117 contactin 1 isoform 1 precursor [Homo sapiens]
Length = 1018
Score = 357 bits (915), Expect = 5e-98
Identities = 281/941 (29%), Positives = 413/941 (43%), Gaps = 102/941 (10%)
Query: 53 ILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYE--GEY 110
+ + C A+ +P P + W N+ ++ D R SM G LVI+ P++ + G Y
Sbjct: 61 VSLNCRARASPFPVYKWRMNNGDVDLTSD-RYSMV--GGNLVIN-----NPDKQKDAGIY 112
Query: 111 QCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIF-W 169
C A N +G S L +P E V V+EG + L C+PP P + + W
Sbjct: 113 YCLASNNYGMVRSTEATLSFGYLDPFPPEERPEVRVKEGKGMVLLCDPPYHFPDDLSYRW 172
Query: 170 MSSSMEP-ITQDKR--VSQGHNGDLYFSNVMLQDMQTDYSCNARF-HFTHTIQQK--NPF 223
+ + IT DKR VSQ NG+LY +NV D + +YSC T ++ K
Sbjct: 173 LLNEFPVFITMDKRRFVSQ-TNGNLYIANVEASD-KGNYSCFVSSPSITKSVFSKFIPLI 230
Query: 224 TLKVLTNHPYNDSSLRNHPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASG 283
+ T PY + D+Y+ L G ++ LEC A G
Sbjct: 231 PIPERTTKPYPADIVVQFKDVYA-----------------------LMGQNVTLECFALG 267
Query: 284 VPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVR 343
P PDI W K +PS A+ L+I N+ ED G Y C A N G +H +
Sbjct: 268 NPVPDIRWRKVLEPMPS-TAEISTSGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIY 326
Query: 344 VKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDT 403
V+A P W++ + + G D C A G P PT++W+ NG G+
Sbjct: 327 VQAFPEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRWLKNGYAYHK----------GEL 376
Query: 404 IIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRM-LSPRNQLIRVILYNRTRLD 462
++ D + +YQC N +G + ANA + +L + P ++P + I R ++
Sbjct: 377 RLY-DVTFENAGMYQCIAENTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIE 435
Query: 463 CPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAE 522
C +P P W K G ++ ++E+GSLEI I + D GIYTC A N GKA
Sbjct: 436 CKPKAAPKPKFSWSK-GTEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKAN 494
Query: 523 NQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSW--------LKDDEP 574
+ L + DPTRI P + G ++C DP+L LT W +
Sbjct: 495 STGTLVITDPTRIILAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVIDFNKENI 554
Query: 575 LYIGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAAL 634
Y N M + L I + G YTC A T +D A A L V
Sbjct: 555 HYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASADLVV-------------- 600
Query: 635 PKGRPDRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYP- 693
+G P P L + D+ SV LTW G N+SPI+ Y +Q + W D P
Sbjct: 601 -RGPPGPPGGLRIEDIRATSVALTWSRGSDNHSPISKYTIQTK--TILSDDWKDAKTDPP 657
Query: 694 ---GSVNSA-VLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEG 749
G++ +A + L P++ Y+FRV+A N +G PS+PS R +T GA P P DV G G
Sbjct: 658 IIEGNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGG 717
Query: 750 TRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETREAWNNVTVWG---SRYVVGQTPV-- 804
R + ITW P++ +G N YIV ++ + E W VTV RYV +
Sbjct: 718 GRNRELTITWAPLSREYHYGNNFGYIVAFKPFDGEE-WKKVTVTNPDTGRYVHKDETMSP 776
Query: 805 YVPYEIRVQAENDFGKGPEPESVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWNRVYSDT 864
++++V+A N+ G GP + S +D P APTEV V+V++S+ IS+ W V
Sbjct: 777 STAFQVKVKAFNNKGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHWEHVLEKI 836
Query: 865 VQGQLREYRAYYWRESSLLKNLWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNG 924
V+ Y A + +E + + SQ+ + L P + Y +E+ N
Sbjct: 837 VESYQIRYWAAHDKEEAANRVQVTSQEYSAR----------LENLLPDTQYFIEVGACNS 886
Query: 925 RGDGPRSETKEFTTPEGVPSAPRRFRVRQPNLETINLEWDH 965
G GP S+ E T + PS P R + + WDH
Sbjct: 887 AGCGPPSDMIEAFTKKAPPSQPPRIISSVRSGSRYIITWDH 927
Score = 68.2 bits (165), Expect = 5e-11
Identities = 92/403 (22%), Positives = 143/403 (35%), Gaps = 57/403 (14%)
Query: 25 IEIPMDLTQP-PTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPR 83
I IP T+P P KD N+ +EC A GNP P W + + P
Sbjct: 230 IPIPERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRK-----VLEPMPS 284
Query: 84 VSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDP 143
+ SG ++ F E EG Y+C A N G ++ R+ V P W E+++
Sbjct: 285 TAEISTSGAVLKIFNI---QLEDEGIYECEAENIRGKD-KHQARIYVQAFPEW-VEHIND 339
Query: 144 VVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQT 203
V G+ L C G P P I W+ K H G+L +V ++
Sbjct: 340 TEVDIGSDLYWPC-VATGKPIPTIRWL----------KNGYAYHKGELRLYDVTFENAGM 388
Query: 204 DYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRNHPDMYSARGVAERTPSFMYPQGT 263
Y C A + LK+L P E P
Sbjct: 389 -YQCIAENTYGAIYANAE---LKILALAP-----------------TFEMNP-------M 420
Query: 264 ASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSG 323
+ +G +++EC P P +W K L + + +L I N++ D G
Sbjct: 421 KKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEWLVNSSRILIWEDGSLEINNITRNDGG 480
Query: 324 EYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNP--KPTVQW 381
Y C A N G T ++ + + P N + GE+ + C A+ +P T W
Sbjct: 481 IYTCFAENNRGKANSTGTLVITDPTRIILAPINADITVGENATMQCAASFDPALDLTFVW 540
Query: 382 MVNGEPLQSAPPNPNRE-----VAGDTIIFRDTQISSRAVYQC 419
NG + N + + + ++ R+ Q+ Y C
Sbjct: 541 SFNGYVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTC 583
Score = 50.8 bits (120), Expect = 7e-06
Identities = 40/160 (25%), Positives = 69/160 (43%), Gaps = 8/160 (5%)
Query: 455 LYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVA 514
L + L+C SP P +W N +L Y + + +++D GIY C+A
Sbjct: 57 LEGKVSLNCRARASPFPVYKWRMNNGDVDLTSDRYSMVGGNLVINNPDKQKDAGIYYCLA 116
Query: 515 TNILG---KAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKD 571
+N G E + DP PE +V + G + L C + L+ WL +
Sbjct: 117 SNNYGMVRSTEATLSFGYLDPFPPEERPEVRV-KEGKGMVLLCDPPYHFPDDLSYRWLLN 175
Query: 572 DEPLYI----GNRMKKEDDSLTIFGVAERDQGSYTCVAST 607
+ P++I + + + +L I V D+G+Y+C S+
Sbjct: 176 EFPVFITMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSS 215
Score = 36.6 bits (83), Expect = 0.15
Identities = 42/214 (19%), Positives = 77/214 (35%), Gaps = 13/214 (6%)
Query: 836 PRAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQA 895
P P +++ + +T+++L W+R + Y + ++L + W K
Sbjct: 603 PPGPPGGLRIEDIRATSVALTWSRGSDNH-----SPISKYTIQTKTILSDDWKDAKTDPP 657
Query: 896 SFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDG-PRSETKEFTTPEGVPS-APRRFRVRQ 953
G+ L P+ Y+ +V N G G P + T P+ AP
Sbjct: 658 IIEGNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGG 717
Query: 954 PNLETINLEWD--HPEHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPV 1011
+ + W E+ G GY + + F+G + K V N + + P
Sbjct: 718 GRNRELTITWAPLSREYHYGNNFGYIVAFKPFDGEEWKKVTVTNPDTGRYVHKDETMSPS 777
Query: 1012 SRYRFTLSARTQVGSGE----AVTEESPAPPNEA 1041
+ ++ + A G G AV + P+EA
Sbjct: 778 TAFQVKVKAFNNKGDGPYSLVAVINSAQDAPSEA 811
>gi|28373119 contactin 1 isoform 2 precursor [Homo sapiens]
Length = 1007
Score = 357 bits (915), Expect = 5e-98
Identities = 281/941 (29%), Positives = 413/941 (43%), Gaps = 102/941 (10%)
Query: 53 ILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYE--GEY 110
+ + C A+ +P P + W N+ ++ D R SM G LVI+ P++ + G Y
Sbjct: 50 VSLNCRARASPFPVYKWRMNNGDVDLTSD-RYSMV--GGNLVIN-----NPDKQKDAGIY 101
Query: 111 QCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIF-W 169
C A N +G S L +P E V V+EG + L C+PP P + + W
Sbjct: 102 YCLASNNYGMVRSTEATLSFGYLDPFPPEERPEVRVKEGKGMVLLCDPPYHFPDDLSYRW 161
Query: 170 MSSSMEP-ITQDKR--VSQGHNGDLYFSNVMLQDMQTDYSCNARF-HFTHTIQQK--NPF 223
+ + IT DKR VSQ NG+LY +NV D + +YSC T ++ K
Sbjct: 162 LLNEFPVFITMDKRRFVSQ-TNGNLYIANVEASD-KGNYSCFVSSPSITKSVFSKFIPLI 219
Query: 224 TLKVLTNHPYNDSSLRNHPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASG 283
+ T PY + D+Y+ L G ++ LEC A G
Sbjct: 220 PIPERTTKPYPADIVVQFKDVYA-----------------------LMGQNVTLECFALG 256
Query: 284 VPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVR 343
P PDI W K +PS A+ L+I N+ ED G Y C A N G +H +
Sbjct: 257 NPVPDIRWRKVLEPMPS-TAEISTSGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIY 315
Query: 344 VKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDT 403
V+A P W++ + + G D C A G P PT++W+ NG G+
Sbjct: 316 VQAFPEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRWLKNGYAYHK----------GEL 365
Query: 404 IIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRM-LSPRNQLIRVILYNRTRLD 462
++ D + +YQC N +G + ANA + +L + P ++P + I R ++
Sbjct: 366 RLY-DVTFENAGMYQCIAENTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIE 424
Query: 463 CPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAE 522
C +P P W K G ++ ++E+GSLEI I + D GIYTC A N GKA
Sbjct: 425 CKPKAAPKPKFSWSK-GTEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKAN 483
Query: 523 NQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSW--------LKDDEP 574
+ L + DPTRI P + G ++C DP+L LT W +
Sbjct: 484 STGTLVITDPTRIILAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVIDFNKENI 543
Query: 575 LYIGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAAL 634
Y N M + L I + G YTC A T +D A A L V
Sbjct: 544 HYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASADLVV-------------- 589
Query: 635 PKGRPDRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYP- 693
+G P P L + D+ SV LTW G N+SPI+ Y +Q + W D P
Sbjct: 590 -RGPPGPPGGLRIEDIRATSVALTWSRGSDNHSPISKYTIQTK--TILSDDWKDAKTDPP 646
Query: 694 ---GSVNSA-VLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEG 749
G++ +A + L P++ Y+FRV+A N +G PS+PS R +T GA P P DV G G
Sbjct: 647 IIEGNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGG 706
Query: 750 TRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETREAWNNVTVWG---SRYVVGQTPV-- 804
R + ITW P++ +G N YIV ++ + E W VTV RYV +
Sbjct: 707 GRNRELTITWAPLSREYHYGNNFGYIVAFKPFDGEE-WKKVTVTNPDTGRYVHKDETMSP 765
Query: 805 YVPYEIRVQAENDFGKGPEPESVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWNRVYSDT 864
++++V+A N+ G GP + S +D P APTEV V+V++S+ IS+ W V
Sbjct: 766 STAFQVKVKAFNNKGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHWEHVLEKI 825
Query: 865 VQGQLREYRAYYWRESSLLKNLWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNG 924
V+ Y A + +E + + SQ+ + L P + Y +E+ N
Sbjct: 826 VESYQIRYWAAHDKEEAANRVQVTSQEYSAR----------LENLLPDTQYFIEVGACNS 875
Query: 925 RGDGPRSETKEFTTPEGVPSAPRRFRVRQPNLETINLEWDH 965
G GP S+ E T + PS P R + + WDH
Sbjct: 876 AGCGPPSDMIEAFTKKAPPSQPPRIISSVRSGSRYIITWDH 916
Score = 68.2 bits (165), Expect = 5e-11
Identities = 92/403 (22%), Positives = 143/403 (35%), Gaps = 57/403 (14%)
Query: 25 IEIPMDLTQP-PTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPR 83
I IP T+P P KD N+ +EC A GNP P W + + P
Sbjct: 219 IPIPERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRK-----VLEPMPS 273
Query: 84 VSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDP 143
+ SG ++ F E EG Y+C A N G ++ R+ V P W E+++
Sbjct: 274 TAEISTSGAVLKIFNI---QLEDEGIYECEAENIRGKD-KHQARIYVQAFPEW-VEHIND 328
Query: 144 VVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQT 203
V G+ L C G P P I W+ K H G+L +V ++
Sbjct: 329 TEVDIGSDLYWPC-VATGKPIPTIRWL----------KNGYAYHKGELRLYDVTFENAGM 377
Query: 204 DYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRNHPDMYSARGVAERTPSFMYPQGT 263
Y C A + LK+L P E P
Sbjct: 378 -YQCIAENTYGAIYANAE---LKILALAP-----------------TFEMNP-------M 409
Query: 264 ASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSG 323
+ +G +++EC P P +W K L + + +L I N++ D G
Sbjct: 410 KKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEWLVNSSRILIWEDGSLEINNITRNDGG 469
Query: 324 EYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNP--KPTVQW 381
Y C A N G T ++ + + P N + GE+ + C A+ +P T W
Sbjct: 470 IYTCFAENNRGKANSTGTLVITDPTRIILAPINADITVGENATMQCAASFDPALDLTFVW 529
Query: 382 MVNGEPLQSAPPNPNRE-----VAGDTIIFRDTQISSRAVYQC 419
NG + N + + + ++ R+ Q+ Y C
Sbjct: 530 SFNGYVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTC 572
Score = 50.8 bits (120), Expect = 7e-06
Identities = 40/160 (25%), Positives = 69/160 (43%), Gaps = 8/160 (5%)
Query: 455 LYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVA 514
L + L+C SP P +W N +L Y + + +++D GIY C+A
Sbjct: 46 LEGKVSLNCRARASPFPVYKWRMNNGDVDLTSDRYSMVGGNLVINNPDKQKDAGIYYCLA 105
Query: 515 TNILG---KAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKD 571
+N G E + DP PE +V + G + L C + L+ WL +
Sbjct: 106 SNNYGMVRSTEATLSFGYLDPFPPEERPEVRV-KEGKGMVLLCDPPYHFPDDLSYRWLLN 164
Query: 572 DEPLYI----GNRMKKEDDSLTIFGVAERDQGSYTCVAST 607
+ P++I + + + +L I V D+G+Y+C S+
Sbjct: 165 EFPVFITMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSS 204
Score = 36.6 bits (83), Expect = 0.15
Identities = 42/214 (19%), Positives = 77/214 (35%), Gaps = 13/214 (6%)
Query: 836 PRAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQA 895
P P +++ + +T+++L W+R + Y + ++L + W K
Sbjct: 592 PPGPPGGLRIEDIRATSVALTWSRGSDNH-----SPISKYTIQTKTILSDDWKDAKTDPP 646
Query: 896 SFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDG-PRSETKEFTTPEGVPS-APRRFRVRQ 953
G+ L P+ Y+ +V N G G P + T P+ AP
Sbjct: 647 IIEGNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGG 706
Query: 954 PNLETINLEWD--HPEHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPV 1011
+ + W E+ G GY + + F+G + K V N + + P
Sbjct: 707 GRNRELTITWAPLSREYHYGNNFGYIVAFKPFDGEEWKKVTVTNPDTGRYVHKDETMSPS 766
Query: 1012 SRYRFTLSARTQVGSGE----AVTEESPAPPNEA 1041
+ ++ + A G G AV + P+EA
Sbjct: 767 TAFQVKVKAFNNKGDGPYSLVAVINSAQDAPSEA 800
>gi|75709184 contactin 3 [Homo sapiens]
Length = 1028
Score = 355 bits (910), Expect = 2e-97
Identities = 274/990 (27%), Positives = 425/990 (42%), Gaps = 102/990 (10%)
Query: 8 PWVHAAFLLCLLSLGGAIEIPMDLTQPPTITKQSAKDHI-VDPRDN-ILIECEAKGNPAP 65
PW L + LGG + L Q P K+ + V D I + CEA+GNP+P
Sbjct: 4 PWKQLILLSFIGCLGGEL-----LLQGPVFIKEPSNSIFPVGSEDKKITLHCEARGNPSP 58
Query: 66 SFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNR 125
+ W N +++ + R + G LV+ G YQCFA N GT +S
Sbjct: 59 HYRWQLNGSDIDMSMEHRYKLN--GGNLVV---INPNRNWDTGTYQCFATNSLGTIVSRE 113
Query: 126 IRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQD--KRV 183
+LQ + + + V V+EG + L C PPP W+ + ++ +R
Sbjct: 114 AKLQFAYLENFKTKMRSTVSVREGQGVVLLCGPPPHSGELSYAWIFNEYPSFVEEDSRRF 173
Query: 184 SQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRNHPD 243
G LY S V D+ +Y+C T+ +P L + ++
Sbjct: 174 VSQETGHLYISKVEPSDVG-NYTCVVTSMVTNARVLGSPTPLVLRSD------------- 219
Query: 244 MYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKA 303
G E +P+ ++ +G + LEC A G P P I W + G S K
Sbjct: 220 --GVMGEYEPKIEVQFPETLPAA----KGSTVKLECFALGNPIPQINWRRSDGLPFSSKI 273
Query: 304 KFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGE 363
K F+ L I N +ED+G Y C+A N G + A P+W+ K++ +A +
Sbjct: 274 KLRKFSGVLEIPNFQQEDAGSYECIAENSRGKNVARGRLTYYAKPHWVQLIKDVEIAVED 333
Query: 364 DGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSN 423
CRA+G PKP+ +W+ NG L ++ + + ++ ++QC N
Sbjct: 334 SLYWECRASGKPKPSYRWLKNGAALVL---EERTQIENGALTISNLSVTDSGMFQCIAEN 390
Query: 424 EHGYLLANAFVSVL-DVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGS 482
+HG + ++A + V+ P +P +L++V + + LDC SP W K G S
Sbjct: 391 KHGLVYSSAELKVVASAPDFSKNPMKKLVQVQVGSLVSLDCKPRASPRALSSW-KKGDVS 449
Query: 483 NLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQ 542
+ + +G L+I + K D G YTC+A N GKA L V +PTRI P +
Sbjct: 450 VQEHERISLLNDGGLKIANVTKADAGTYTCMAENQFGKANGTTHLVVTEPTRITLAPSNM 509
Query: 543 VARRGTTVQLECRVKHDPSLKLTVSW--------LKDDEPLYIGNRMKKEDDS----LTI 590
G +V L C+V+HDP L + +W K D G+ +K S L I
Sbjct: 510 DVSVGESVILPCQVQHDPLLDIIFTWYFNGALADFKKD-----GSHFEKVGGSSSGDLMI 564
Query: 591 FGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDL 650
+ + G Y C+ T +D + A L V +G P P ++++ ++
Sbjct: 565 RNIQLKHSGKYVCMVQTGVDSVSSAADLIV---------------RGSPGPPENVKVDEI 609
Query: 651 AERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVN-----SAVLRLSP 705
+ + +L+W G N+SP+ Y +Q F G W + P ++ + V+ L+P
Sbjct: 610 TDTTAQLSWKEGKDNHSPVISYSIQ-ARTPFSVG-WQTVTTVPEVIDGKTHTATVVELNP 667
Query: 706 YVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNAT 765
+V Y+FRV+A N++G PSLPSE+ RT A PE P +V G G ++ + ITW P+
Sbjct: 668 WVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVPEVPPSEVNGGGGSRSELVITWDPVPEE 727
Query: 766 SAFGPNLRYIVKWRRRETREAWNNVTVWGSRYVVG-QTPVYV----------PYEIRVQA 814
G Y+V +R VT W V TP YV PYE++V
Sbjct: 728 LQNGEGFGYVVAFRPL-------GVTTWIQTVVTSPDTPRYVFRNESIVPYSPYEVKVGV 780
Query: 815 ENDFGKGPEPESVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRA 874
N+ G+GP +S E+ P AP++V ++S+ I + WN + G L Y
Sbjct: 781 YNNKGEGPFSPVTTVFSAEEEPTVAPSQVSANSLSSSEIEVSWNTIPWKLSNGHLLGYEV 840
Query: 875 YYWRESSLLKNLWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSETK 934
YW K S+ + + RLRG+ S L Y+ + N G GP S T
Sbjct: 841 RYWNGGG--KEESSSKMKVAGNETSARLRGLKSNLAYYTAVR----AYNSAGAGPFSATV 894
Query: 935 EFTTPEGVPSAPRRFRVRQPNLETINLEWD 964
TT + PS P V + L W+
Sbjct: 895 NVTTKKTPPSQPPGNVVWNATDTKVLLNWE 924
Score = 32.0 bits (71), Expect = 3.6
Identities = 27/107 (25%), Positives = 39/107 (36%), Gaps = 6/107 (5%)
Query: 941 GVPSAPRRFRVRQPNLETINLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIV----ENF 996
G P P +V + T L W + + +I Y+++ A VG Q V E
Sbjct: 596 GSPGPPENVKVDEITDTTAQLSWKEGKDNHSPVISYSIQ--ARTPFSVGWQTVTTVPEVI 653
Query: 997 SPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESPAPPNEATP 1043
TV +P Y F + A ++G GE EA P
Sbjct: 654 DGKTHTATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVP 700
>gi|7657361 contactin 6 [Homo sapiens]
Length = 1028
Score = 311 bits (798), Expect = 2e-84
Identities = 249/953 (26%), Positives = 403/953 (42%), Gaps = 75/953 (7%)
Query: 50 RDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGE 109
+ +++ C A G P+P + W +N + R G+L I+ ++ G
Sbjct: 43 KSEVILNCAANGYPSPHYRWKQNGTDIDFTMS--YHYRLDGGSLAIN---SPHTDQDIGM 97
Query: 110 YQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFW 169
YQC A N GT LS + +LQ + + + V V+EG + L C PPP W
Sbjct: 98 YQCLATNLLGTILSRKAKLQFAYIEDFETKTRSTVSVREGQGVVLLCGPPPHFGDLSYAW 157
Query: 170 MSSSMEPITQD--KRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKV 227
+ Q+ +R G+LY + V D+ +Y+C Q P L
Sbjct: 158 TFNDNPLYVQEDNRRFVSQETGNLYIAKVEPSDVG-NYTCFITNKEAQRSVQGPPTPLVQ 216
Query: 228 LTNHPYNDSSLRNHPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTP 287
T+ G E +P+ ++ + + LEC A G P P
Sbjct: 217 RTD---------------GVMGEYEPKIEVRFPETIQAA----KDSSVKLECFALGNPVP 257
Query: 288 DIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAA 347
DI+W + G K K+ L I N +ED G Y C+ASN G + A
Sbjct: 258 DISWRRLDGSPLPGKVKYSKSQAILEIPNFQQEDEGFYECIASNLRGRNLAKGQLIFYAP 317
Query: 348 PYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFR 407
P W + +N L+ ++ C+A+G P P W+ NGE L P ++ T+I
Sbjct: 318 PEWEQKIQNTHLSIYDNLLWECKASGKPNPWYTWLKNGERLN---PEERIQIENGTLIIT 374
Query: 408 DTQISSRAVYQCNTSNEHGYLLANAFVSVL-DVPPRMLSPRNQLIRVILYNRTRLDCPFF 466
+S VYQC N++ + ANA + VL P SP + V + + C
Sbjct: 375 MLNVSDSGVYQCAAENKYQIIYANAELRVLASAPDFSKSPVKKKSFVQVGGDIVIGCKPN 434
Query: 467 GSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVR 526
P + W K G + + E+GSL+I I + D G YTC+ATN G A+N
Sbjct: 435 AFPRAAISW-KRGTETLRQSKRIFLLEDGSLKIYNITRSDAGSYTCIATNQFGTAKNTGS 493
Query: 527 LEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMK---- 582
L VK+ T I P G ++ L C+V HDPS+++ W + + + + +
Sbjct: 494 LIVKERTVITVPPSKMDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFER 553
Query: 583 ---KEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRP 639
+ L I + G Y C T L+ L+ +AD + +G P
Sbjct: 554 IGGESVGDLMIRNIQLHHSGKYLCTVQTTLES------LSAVAD---------IIVRGPP 598
Query: 640 DRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYP-----G 694
P D+++ D++ + +L+W G NNSPI + +Q F G W + P
Sbjct: 599 GPPEDVQVEDISSTTSQLSWRAGPDNNSPIQIFTIQ-TRTPFSVG-WQAVATVPEILNGK 656
Query: 695 SVNSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNN 754
+ N+ V+ LSP+V Y+FRV+A N +G PS PSE RT + P P ++ G G ++
Sbjct: 657 TYNATVVGLSPWVEYEFRVVAGNSIGIGEPSEPSELLRTKASVPVVAPVNIHGGGGSRSE 716
Query: 755 MEITWTPMNATSAFGPNLRYIVKWRRRETREAWNN---VTVWGSRYVVGQTPV--YVPYE 809
+ ITW + G YI+ +R + W+ +V SR+V + P+E
Sbjct: 717 LVITWESIPEELQNGEGFGYIIMFRPVGS-TTWSKEKVSSVESSRFVYRNESIIPLSPFE 775
Query: 810 IRVQAENDFGKGPEPESVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQL 869
++V N+ G+G I YSGED P+ AP ++ +++ + + WN + + G++
Sbjct: 776 VKVGVYNNEGEGSLSTVTIVYSGEDEPQLAPRGTSLQSFSASEMEVSWNAIAWNRNTGRV 835
Query: 870 REYRAYYWRESSLLKNLWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDGP 929
Y YW + S K + + R + + G+ + +++ + N G GP
Sbjct: 836 LGYEVLYWTDDS--KESMIGKIRVSGNVTTKNITGLKANTIYFASVR----AYNTAGTGP 889
Query: 930 RSETKEFTTPEGVPSAPRRFRVRQPNLETINLEWDHPE--HPNGIMIGYTLKY 980
S TT + PS P + + L W+H + ++GY + Y
Sbjct: 890 SSPPVNVTTKKSPPSQPPANIAWKLTNSKLCLNWEHVKTMENESEVLGYKILY 942
Score = 78.6 bits (192), Expect = 3e-14
Identities = 101/424 (23%), Positives = 171/424 (40%), Gaps = 54/424 (12%)
Query: 23 GAIEIPMDLTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDP 82
G E +++ P TI Q+AKD ++ +EC A GNP P W R + P
Sbjct: 223 GEYEPKIEVRFPETI--QAAKD------SSVKLECFALGNPVPDISWRR------LDGSP 268
Query: 83 RVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLD 142
+ S + I +E EG Y+C A N G L+ + +L P W ++ +
Sbjct: 269 LPGKVKYSKSQAI-LEIPNFQQEDEGFYECIASNLRGRNLA-KGQLIFYAPPEW-EQKIQ 325
Query: 143 PVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQ 202
+ L +C G P+P W+ + E + ++R+ Q NG L + + + D
Sbjct: 326 NTHLSIYDNLLWECK-ASGKPNPWYTWLKNG-ERLNPEERI-QIENGTLIITMLNVSDSG 382
Query: 203 TDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRNHPDMYSARGVAERTPSFMYPQG 262
Y C A +N + + Y ++ LR V P F
Sbjct: 383 V-YQCAA----------ENKYQI------IYANAELR----------VLASAPDFS-KSP 414
Query: 263 TASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDS 322
V G D+++ C + P I+W + L K F + +L+I N++ D+
Sbjct: 415 VKKKSFVQVGGDIVIGCKPNAFPRAAISWKRGTETLRQSKRIFLLEDGSLKIYNITRSDA 474
Query: 323 GEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTV--Q 380
G Y C+A+N+ G+ ++T S+ VK P + + GE L C+ + +P V
Sbjct: 475 GSYTCIATNQFGTAKNTGSLIVKERTVITVPPSKMDVTVGESIVLPCQVSHDPSIEVVFV 534
Query: 381 WMVNGEPLQSAPPNPNRE-VAGDTI---IFRDTQISSRAVYQCNTSNEHGYLLANAFVSV 436
W NG+ + + E + G+++ + R+ Q+ Y C L A A + V
Sbjct: 535 WFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLHHSGKYLCTVQTTLESLSAVADIIV 594
Query: 437 LDVP 440
P
Sbjct: 595 RGPP 598
Score = 33.9 bits (76), Expect = 0.95
Identities = 44/231 (19%), Positives = 81/231 (35%), Gaps = 16/231 (6%)
Query: 836 PRAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQA 895
P P +V+V ++ST L W + Q+ + + + W +
Sbjct: 597 PPGPPEDVQVEDISSTTSQLSWRAGPDNNSPIQI-----FTIQTRTPFSVGWQAVATVPE 651
Query: 896 SFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSETKEFT-TPEGVPS-APRRFRVRQ 953
G V L P+ Y+ +V N G G SE E T VP AP
Sbjct: 652 ILNGKTYNATVVGLSPWVEYEFRVVAGNSIGIGEPSEPSELLRTKASVPVVAPVNIHGGG 711
Query: 954 PNLETINLEWDH--PEHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPV 1011
+ + + W+ E NG GY + + T K+ V + ++ + + P+
Sbjct: 712 GSRSELVITWESIPEELQNGEGFGYIIMFRPVGSTTWSKEKVSSVESSRFVYRNESIIPL 771
Query: 1012 SRYRFTLSARTQVGSGEAVT-------EESPAPPNEATPTAAYTNNQADIA 1055
S + + G G T E+ P T +++ ++ +++
Sbjct: 772 SPFEVKVGVYNNEGEGSLSTVTIVYSGEDEPQLAPRGTSLQSFSASEMEVS 822
>gi|119220552 sidekick 1 [Homo sapiens]
Length = 2213
Score = 256 bits (655), Expect = 7e-68
Identities = 241/951 (25%), Positives = 386/951 (40%), Gaps = 66/951 (6%)
Query: 108 GEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVI 167
G Y+C RN+ G L + +QV+ + + V Q G L P P P +
Sbjct: 165 GFYRCVVRNRMGALLQRKSEVQVAYMGSFMDTDQRKTVSQ-GRAAILNLLPITSYPRPQV 223
Query: 168 FWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKV 227
W + I ++ N V+L +D A ++ + +KN
Sbjct: 224 TWFREGHKIIPSNRIAITLEN-----QLVILATTTSD----AGAYYVQAVNEKNG----- 269
Query: 228 LTNHPYNDSSLRNHPDMYSARGVAER-TPSFMYPQGTASSQMVLRGMDLLLECIASGVPT 286
N +S H + G E P+ + P G S +V + LECIAS P
Sbjct: 270 -----ENKTSPFIHLSIARDVGTPETMAPTIVVPPGNRS--VVAGSSETTLECIASARPV 322
Query: 287 PDIA--WYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFC---LASNKMGSIRHTIS 341
D++ W + G + S +F + L I+N + D+G Y C L + R T
Sbjct: 323 EDLSVTWKRNGVRITSG---LHSFGRRLTISNPTSADTGPYVCEAALPGSAFEPARATAF 379
Query: 342 VRVKAAPYWLDEPKNLILAPGEDG-RLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREV- 399
+ + PY+ EP++ I A E+ + C+A G P PT+QW + + S NP +V
Sbjct: 380 LFIIEPPYFTAEPESRISAEVEETVDIGCQAMGVPLPTLQWYKDAISI-SRLQNPRYKVL 438
Query: 400 AGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRT 459
A + + + ++QC SNE G + + ++ V ++ P + + R V
Sbjct: 439 ASGGLRIQKLRPEDSGIFQCFASNEGGEIQTHTYLDVTNIAP-VFTQRPVDTTVTDGMTA 497
Query: 460 RLDCPFFGSPIPTLRWFKNGQ---GSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATN 516
L C G+P P + W + ++ + + E+G L+I + +D G YTC A N
Sbjct: 498 ILRCEVSGAPKPAITWKRENHILASGSVRIPRFMLLESGGLQIAPVFIQDAGNYTCYAAN 557
Query: 517 ILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDD---E 573
G L V + T I PED V +GTT L C HDP + L W KD+
Sbjct: 558 TEGSLNASATLTVWNRTSIVHPPEDHVVIKGTTATLHCGATHDPRVSLRYVWKKDNVALT 617
Query: 574 PLYIGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAA 633
P + ++D SL I D G Y+C +E D A L V+ +P N L +
Sbjct: 618 PSSTSRIVVEKDGSLLISQTWSGDIGDYSCEIVSEGGNDSRMARLEVIELPHSPQNLLVS 677
Query: 634 LPKGRPDRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYP 693
+V L+W+ NSPI Y+V+ E+ P H + P
Sbjct: 678 PNSSH-------------SHAVVLSWVRPFDGNSPILYYIVELSENN-SPWKVHLSNVGP 723
Query: 694 GSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKN 753
V L+P YQFRV A+NEVG S + R PP + P ++ G
Sbjct: 724 EMTGVTVSGLTPARTYQFRVCAVNEVGRGQYSAETSRLMLPEEPPSAPPKNIVASGRTNQ 783
Query: 754 NMEITWTPMNATSAFGPNLRYIVKWRRRETREAW--NNVTVWGSRY-VVGQTPVYVPYEI 810
++ + W P T G YI+++R + N+T Y +V ++ YEI
Sbjct: 784 SIMVQWQPPPETEHNGVLRGYILRYRLAGLPGEYQQRNITSPEVNYCLVTDLIIWTQYEI 843
Query: 811 RVQAENDFGKGPEPESVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQLR 870
+V A N G G +V Y+ + P A P V+ +NST I WN + G +
Sbjct: 844 QVAAYNGAGLGVFSRAVTEYTLQGVPTAPPQNVQTEAVNSTTIQFLWNPPPQQFINGINQ 903
Query: 871 EYRAYYWRESSLLKNLWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDGPR 930
Y+ W + V+ F G G ++ L ++ Y ++ GDGP
Sbjct: 904 GYKLLAWPADAPEA---VTVVTIAPDFHGVH-HGHITNLKKFTAYFTSVLCFTTPGDGPP 959
Query: 931 SETKEFTTPEGVPSAPRRFRVRQPNLETINLEWDHPEHPNGIMIGYTLKYVAFNGTKVGK 990
S + T E P A + ++ + W P NGI+ GY + + + +
Sbjct: 960 STPQLVWTQEDKPGAVGHLSFTEILDTSLKVSWQEPLEKNGIITGYQISWEVYG--RNDS 1017
Query: 991 QIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSG--EAVTEESPAPPN 1039
++ + ++ +Q ++ Y ++A T VG+G + T S PP+
Sbjct: 1018 RLTHTLNSTTHEYKIQGLSSLTTYTIDVAAVTAVGTGLVTSSTISSGVPPD 1068
Score = 132 bits (331), Expect = 3e-30
Identities = 108/427 (25%), Positives = 188/427 (44%), Gaps = 25/427 (5%)
Query: 632 AALPKGRPDRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEE----DQFQPGVWH 687
+ +P P P +L +++++ RS L + PG + I+ ++V+ + D+ + +
Sbjct: 1063 SGVPPDLPGAPSNLVISNISPRSATLQFRPGYDGKTSISRWIVEGQVGAIGDEEEWVTLY 1122
Query: 688 DHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKG 747
+ P + + L+PY +Y+FR+ +N VG S S S +T APP+ P V
Sbjct: 1123 EEENEPDAQMLEIPNLTPYTHYRFRMKQVNIVGPSPYSPSSRVIQTLQAPPDVAPTSVTV 1182
Query: 748 EGTRKNNMEITWTPMNATSAFG--PNLRYIVKWRRRETREAWNNVTVWGS---RYVVGQT 802
+ ++ + W P+ + G ++ Y +K+ R + + + V + + +
Sbjct: 1183 RTASETSLRLRWVPLPDSQYNGNPESVGYRIKYWRSDLQSSAVAQVVSDRLEREFTIEEL 1242
Query: 803 PVYVPYEIRVQAENDFGKGPEPESVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWNRVYS 862
++ YE+++QA N G GP E V G + E P AAP V ++ST I L W V
Sbjct: 1243 EEWMEYELQMQAFNAVGAGPWSEVVRGRTRESVPSAAPENVSAEAVSSTQILLTWTSVPE 1302
Query: 863 DTVQGQLREYRAYYWRESSLLKNLWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVV 922
G + Y+ + R L + R +++ L + Y+L+++
Sbjct: 1303 QDQNGLILGYKILF-RAKDL-----DPEPRSHIVRGNHTQSALLAGLRKFVLYELQVLAF 1356
Query: 923 NGRGDG-PRSETKEFTTPEGVPSAPRRFRVRQPNLETINLEWDHPEHPNGIMIGYTLKYV 981
G+G P + T + P P R + L ++ + W PE PNGI++GY + Y
Sbjct: 1357 TRIGNGVPSTPLILERTKDDAPGPPVRLVFPEVRLTSVRIVWQPPEEPNGIILGYQIAYR 1416
Query: 982 AFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAV--------TEE 1033
+ + VE +FT P S Y F LSA+T+ G GE + E
Sbjct: 1417 LASSSPHTFTTVE-VGATVRQFTATDLAPESAYIFRLSAKTRQGWGEPLEATVITTEKRE 1475
Query: 1034 SPAPPNE 1040
PAPP E
Sbjct: 1476 RPAPPRE 1482
Score = 126 bits (317), Expect = 1e-28
Identities = 112/437 (25%), Positives = 177/437 (40%), Gaps = 40/437 (9%)
Query: 638 RPDRPRDLEL--TDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGS 695
RP PR+L + ++ RS+RL W+PG SPI + +Q E G W +S
Sbjct: 1476 RPAPPRELLVPQAEVTARSLRLQWVPGSDGASPIRYFTMQVRE--LPRGEWQTYSSSISH 1533
Query: 696 VNSAVL--RLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKN 753
+A + RL P+ +Y+ R+ A N++G S S +E T P PG V +
Sbjct: 1534 EATACVVDRLRPFTSYKLRLKATNDIGDSDFSSETEAVTTLQDVPGEPPGSVSATPHTTS 1593
Query: 754 NMEITWTPMNATSAFGPNLRYIVKWRRRETREAWNN--------------VTVWGSRYVV 799
++ I W P S G Y + +R E +T S V
Sbjct: 1594 SVLIQWQPPRDESLNGLLQGYRIYYRELEYEAGSGTEAKTLKNPIALHAELTAQSSFKTV 1653
Query: 800 GQTPV-----------YVPYEIRVQAENDFGKGPEPESVIGYSGEDYPRAAPTEVKVRVM 848
+ Y YE+ + A N G+ P V + GE P AP V+V +
Sbjct: 1654 NSSSTSTMCELTHLKKYRRYEVIMTAYNIIGESPASAPVEVFVGEAAPAMAPQNVQVTPL 1713
Query: 849 NSTAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQASFPGDRLRGVVSR 908
++ + + W+ ++ G ++ Y+ YYW S +N K P RL+ + S
Sbjct: 1714 TASQLEVTWDPPPPESQNGNIQGYKIYYWEADS--QNETEKMKVLFLPEPVVRLKNLTS- 1770
Query: 909 LFPYSNYKLEMVVVNGRGDGPRSETKEFTTPEGVPSAPRRFRVRQPNLETINLEWDHPEH 968
++ Y + + N GDGP+S+ ++ T + P AP + T+N+ W P
Sbjct: 1771 ---HTKYLVSISAFNAAGDGPKSDPQQGRTHQAAPGAPSFLAFSEITSTTLNVSWGEPAA 1827
Query: 969 PNGIMIGYTLKYVAFNGTK-VGKQIVENFSPN-QTKFTVQRTDPVSRYRFTLSARTQVGS 1026
NGI+ GY + Y + V K + N Q V+ Y F + ART +
Sbjct: 1828 ANGILQGYRVVYEPLAPVQGVSKVVTVEVRGNWQRWLKVRDLTKGVTYFFRVQART-ITY 1886
Query: 1027 GEAVTEESPAPPNEATP 1043
G + A P E +P
Sbjct: 1887 GPELQANITAGPAEGSP 1903
Score = 111 bits (277), Expect = 5e-24
Identities = 229/1085 (21%), Positives = 405/1085 (37%), Gaps = 162/1085 (14%)
Query: 31 LTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRS 90
+ +PP T + + + + I C+A G P P+ W +++ + ++PR +
Sbjct: 382 IIEPPYFTAEPESRISAEVEETVDIGCQAMGVPLPTLQWYKDAISISRLQNPRYKVLASG 441
Query: 91 GTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGA 150
G + RPE+ G +QCFA N+ G ++ + +P++ + +D V +G
Sbjct: 442 GLRIQKL----RPED-SGIFQCFASNEGGEIQTHTYLDVTNIAPVFTQRPVD-TTVTDGM 495
Query: 151 PLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQG---HNGDLYFSNVMLQDMQTDYSC 207
L+C G P P I W + + R+ + +G L + V +QD +Y+C
Sbjct: 496 TAILRCE-VSGAPKPAITWKRENHILASGSVRIPRFMLLESGGLQIAPVFIQD-AGNYTC 553
Query: 208 NARFHFTHTIQQKN-PFTLKVLTNHPYNDSSLRNHPDMYSARGVAERTPSFMYPQGTASS 266
A +T N TL V +N +S+ + P+
Sbjct: 554 YA----ANTEGSLNASATLTV-----WNRTSIVHPPE----------------------D 582
Query: 267 QMVLRGMDLLLECIASGVPTPDIAWYKKGGDL---PSDKAKF-ENFNKALRITNVSEEDS 322
+V++G L C A+ P + + K ++ PS ++ + +L I+ D
Sbjct: 583 HVVIKGTTATLHCGATHDPRVSLRYVWKKDNVALTPSSTSRIVVEKDGSLLISQTWSGDI 642
Query: 323 GEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDG------RLVCRANGNPK 376
G+Y C ++ G+ + V P+ P+NL+++P V +GN
Sbjct: 643 GDYSCEIVSEGGNDSRMARLEVIELPH---SPQNLLVSPNSSHSHAVVLSWVRPFDGN-S 698
Query: 377 PTVQWMV----NGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTS--NEHGYLLA 430
P + ++V N P + N E+ G T+ + ++ YQ NE G
Sbjct: 699 PILYYIVELSENNSPWKVHLSNVGPEMTGVTV----SGLTPARTYQFRVCAVNEVGRGQY 754
Query: 431 NAFVSVLDVP--PRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGN 488
+A S L +P P P+N ++ RT P P + + + G
Sbjct: 755 SAETSRLMLPEEPPSAPPKN----IVASGRTNQSIMVQWQPPP------ETEHNGVLRGY 804
Query: 489 YHVYENGSL--EIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPT--RIYRMPEDQVA 544
Y L E + + C+ T+++ + ++++ + ++ +
Sbjct: 805 ILRYRLAGLPGEYQQRNITSPEVNYCLVTDLIIWTQYEIQVAAYNGAGLGVFSRAVTEYT 864
Query: 545 RRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKK----------EDDSLTIFGVA 594
+G V+ + T+ +L + P N + + +++T+ +A
Sbjct: 865 LQGVPTAPPQNVQTEAVNSTTIQFLWNPPPQQFINGINQGYKLLAWPADAPEAVTVVTIA 924
Query: 595 ERDQGSYTCVASTELDQDLAKAYLTVLADQATP------TNRLAALPKGRPDRPRDLELT 648
G + T L + A Y T + TP T +L + +P L T
Sbjct: 925 PDFHGVHH-GHITNLKKFTA--YFTSVLCFTTPGDGPPSTPQLVWTQEDKPGAVGHLSFT 981
Query: 649 DLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSA-----VLRL 703
++ + S++++W N IT Y + +E + S+ ++NS + L
Sbjct: 982 EILDTSLKVSWQEPLEKNGIITGYQISWEV------YGRNDSRLTHTLNSTTHEYKIQGL 1035
Query: 704 SPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMN 763
S Y V A+ VG+ L + +SG PP+ G N + +P +
Sbjct: 1036 SSLTTYTIDVAAVTAVGT---GLVTSSTISSGVPPDL-------PGAPSNLVISNISPRS 1085
Query: 764 ATSAFGPNL---RYIVKWRRRETREAWNNVTVWGSRYVVGQTP-----------VYVPYE 809
AT F P I +W A + W + Y P Y Y
Sbjct: 1086 ATLQFRPGYDGKTSISRWIVEGQVGAIGDEEEWVTLYEEENEPDAQMLEIPNLTPYTHYR 1145
Query: 810 IRVQAENDFGKGP-EPESVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQ 868
R++ N G P P S + + + P APT V VR + T++ L+W + G
Sbjct: 1146 FRMKQVNIVGPSPYSPSSRVIQTLQAPPDVAPTSVTVRTASETSLRLRWVPLPDSQYNGN 1205
Query: 869 LRE--YRAYYWRESSLLKNLWVSQKRQQASFPGDRLRG--VVSRLFPYSNYKLEMVVVNG 924
YR YWR Q A DRL + L + Y+L+M N
Sbjct: 1206 PESVGYRIKYWRSD--------LQSSAVAQVVSDRLEREFTIEELEEWMEYELQMQAFNA 1257
Query: 925 RGDGPRSETKEFTTPEGVPS-APRRFRVRQPNLETINLEWDH-PEH-PNGIMIGYTLKYV 981
G GP SE T E VPS AP + I L W PE NG+++GY + +
Sbjct: 1258 VGAGPWSEVVRGRTRESVPSAAPENVSAEAVSSTQILLTWTSVPEQDQNGLILGYKILFR 1317
Query: 982 AFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSG--------EAVTEE 1033
A + + + + Q+ V Y + A T++G+G E ++
Sbjct: 1318 AKDLDPEPRSHIVRGNHTQSALLAGLRKFV-LYELQVLAFTRIGNGVPSTPLILERTKDD 1376
Query: 1034 SPAPP 1038
+P PP
Sbjct: 1377 APGPP 1381
Score = 74.7 bits (182), Expect = 5e-13
Identities = 96/423 (22%), Positives = 164/423 (38%), Gaps = 47/423 (11%)
Query: 639 PDRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNS 698
P P L ++ SVR+ W P + N I Y + + P H+ V +
Sbjct: 1378 PGPPVRLVFPEVRLTSVRIVWQPPEEPNGIILGYQIAYRLASSSP-----HTFTTVEVGA 1432
Query: 699 AVLR-----LSPYVNYQFRVIAINEVGSSHP---SLPSERYRTSGAPPESNPGDVKGEGT 750
V + L+P Y FR+ A G P ++ + R APP V
Sbjct: 1433 TVRQFTATDLAPESAYIFRLSAKTRQGWGEPLEATVITTEKRERPAPPRELL--VPQAEV 1490
Query: 751 RKNNMEITWTPMNATSAFGPNLRYIVKWRRRETREAW----NNVTVWGSRYVVGQTPVYV 806
++ + W P + P +RY R R W ++++ + VV + +
Sbjct: 1491 TARSLRLQWVP--GSDGASP-IRYFTMQVRELPRGEWQTYSSSISHEATACVVDRLRPFT 1547
Query: 807 PYEIRVQAENDFGKGP---EPESVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWNRVYSD 863
Y++R++A ND G E E+V +D P P V ++++ +QW +
Sbjct: 1548 SYKLRLKATNDIGDSDFSSETEAVTTL--QDVPGEPPGSVSATPHTTSSVLIQWQPPRDE 1605
Query: 864 TVQGQLREYRAYY---------WRESSLLKN--LWVSQKRQQASFPGDRLRGV-----VS 907
++ G L+ YR YY E+ LKN ++ Q+SF ++
Sbjct: 1606 SLNGLLQGYRIYYRELEYEAGSGTEAKTLKNPIALHAELTAQSSFKTVNSSSTSTMCELT 1665
Query: 908 RLFPYSNYKLEMVVVNGRGDGPRSETKEFTTPEGVPS-APRRFRVRQPNLETINLEWD-- 964
L Y Y++ M N G+ P S E E P+ AP+ +V + + WD
Sbjct: 1666 HLKKYRRYEVIMTAYNIIGESPASAPVEVFVGEAAPAMAPQNVQVTPLTASQLEVTWDPP 1725
Query: 965 HPEHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQV 1024
PE NG + GY + Y + +++ F P + ++ ++Y ++SA
Sbjct: 1726 PPESQNGNIQGYKIYYWEADSQNETEKMKVLFLP-EPVVRLKNLTSHTKYLVSISAFNAA 1784
Query: 1025 GSG 1027
G G
Sbjct: 1785 GDG 1787
Score = 62.4 bits (150), Expect = 2e-09
Identities = 104/498 (20%), Positives = 189/498 (37%), Gaps = 52/498 (10%)
Query: 622 ADQATPTNRLAALPKGRPDRPRDLELTDLAERSVRLTWIP--GDANNSPITDYVVQFEED 679
+D ++ T + L + P + T SV + W P ++ N + Y + + E
Sbjct: 1562 SDFSSETEAVTTLQDVPGEPPGSVSATPHTTSSVLIQWQPPRDESLNGLLQGYRIYYREL 1621
Query: 680 QFQPGVWHD----------HSKYPG-----SVNSA-------VLRLSPYVNYQFRVIAIN 717
+++ G + H++ +VNS+ + L Y Y+ + A N
Sbjct: 1622 EYEAGSGTEAKTLKNPIALHAELTAQSSFKTVNSSSTSTMCELTHLKKYRRYEVIMTAYN 1681
Query: 718 EVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRY-IV 776
+G S S P E + AP + P +V+ + +E+TW P S G Y I
Sbjct: 1682 IIGESPASAPVEVFVGEAAPAMA-PQNVQVTPLTASQLEVTWDPPPPESQNGNIQGYKIY 1740
Query: 777 KWRRRETREAWNNVTVWGSRYVVGQTPV--YVPYEIRVQAENDFGKGPEPESVIGYSGED 834
W E ++ VV + + Y + + A N G GP+ + G + +
Sbjct: 1741 YWEADSQNETEKMKVLFLPEPVVRLKNLTSHTKYLVSISAFNAAGDGPKSDPQQGRTHQA 1800
Query: 835 YPRAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQ 894
P AP+ + + ST +++ W + G L+ YR Y L + K
Sbjct: 1801 AP-GAPSFLAFSEITSTTLNVSWGEPAA--ANGILQGYRVVY----EPLAPVQGVSKVVT 1853
Query: 895 ASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSETKEFTTP-EGVPSAPRRFRVRQ 953
G+ R + R V GP + P EG P +PR V +
Sbjct: 1854 VEVRGNWQRWLKVRDLTKGVTYFFRVQARTITYGPELQANITAGPAEGSPGSPRDVLVTK 1913
Query: 954 PNLETINLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSR 1013
E + L+W + GY ++ + + V++ + T +T+ D + +
Sbjct: 1914 SASE-LTLQWTEGHSGDTPTTGYVIE-ARPSDEGLWDMFVKDIPRSATSYTLS-LDKLRQ 1970
Query: 1014 ---YRFTLSARTQVGSGEAVTEESPAPPNEATPTAAYTNNQADIATQGWFIGLMCAIALL 1070
Y F + A + G GE P N +T +A +A + WF+ +M +L+
Sbjct: 1971 GVTYEFRVVAVNEAGYGE--------PSNPSTAVSAQV--EAPFYEEWWFLLVMALSSLI 2020
Query: 1071 VLILLIVCFIKRSRGGKY 1088
V++L++ + + KY
Sbjct: 2021 VILLVVFALVLHGQNKKY 2038
Score = 55.8 bits (133), Expect = 2e-07
Identities = 83/374 (22%), Positives = 140/374 (37%), Gaps = 32/374 (8%)
Query: 267 QMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYF 326
Q+ L G L+L C+A G + W + +L + ++++ I ++ + D+G Y
Sbjct: 114 QIHLEGNRLVLTCLAEGSWPLEFKWMRDDSELTTYSSEYKYI-----IPSLQKLDAGFYR 168
Query: 327 CLASNKMGS-IRHTISVRVKAAPYWLDEPKNLILAPGEDGRL-VCRANGNPKPTVQWMVN 384
C+ N+MG+ ++ V+V ++D + ++ G L + P+P V W
Sbjct: 169 CVVRNRMGALLQRKSEVQVAYMGSFMDTDQRKTVSQGRAAILNLLPITSYPRPQVTWFRE 228
Query: 385 GEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNE-HGYLLANAFVSVL------ 437
G + P N + ++ T S Y NE +G + F+ +
Sbjct: 229 GHKI--IPSNRIAITLENQLVILATTTSDAGAYYVQAVNEKNGENKTSPFIHLSIARDVG 286
Query: 438 ---DVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYEN 494
+ P ++ P V + T L+C P+ L G + G +
Sbjct: 287 TPETMAPTIVVPPGNRSVVAGSSETTLECIASARPVEDLSVTWKRNGVRITSGLHSF--G 344
Query: 495 GSLEIKMIRKEDQGIYTCVATNILGKAENQVR----LEVKDPTRIYRMPEDQV-ARRGTT 549
L I D G Y C A + G A R L + +P PE ++ A T
Sbjct: 345 RRLTISNPTSADTGPYVCEAA-LPGSAFEPARATAFLFIIEPPYFTAEPESRISAEVEET 403
Query: 550 VQLECRVKHDPSLKLTVSWLKDDEPL-YIGNRMKK--EDDSLTIFGVAERDQGSYTCVAS 606
V + C+ P T+ W KD + + N K L I + D G + C AS
Sbjct: 404 VDIGCQAMGVP--LPTLQWYKDAISISRLQNPRYKVLASGGLRIQKLRPEDSGIFQCFAS 461
Query: 607 TELDQDLAKAYLTV 620
E + YL V
Sbjct: 462 NEGGEIQTHTYLDV 475
Score = 35.4 bits (80), Expect = 0.33
Identities = 45/193 (23%), Positives = 72/193 (37%), Gaps = 16/193 (8%)
Query: 22 GGAIEIP--MDLTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFF--N 77
GG I+ +D+T + Q D V ++ CE G P P+ W R +
Sbjct: 464 GGEIQTHTYLDVTNIAPVFTQRPVDTTVTDGMTAILRCEVSGAPKPAITWKRENHILASG 523
Query: 78 IAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTA-LSNRIRLQVSKSPLW 136
+ PR + G + + G Y C+A N G+ S + + S +
Sbjct: 524 SVRIPRFMLLESGGLQIAPVFI-----QDAGNYTCYAANTEGSLNASATLTVWNRTSIVH 578
Query: 137 PKENLDPVVVQEGAPLTLQCNP--PPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFS 194
P E D VV+ +G TL C P + ++ + + R+ +G L S
Sbjct: 579 PPE--DHVVI-KGTTATLHCGATHDPRVSLRYVWKKDNVALTPSSTSRIVVEKDGSLLIS 635
Query: 195 NVMLQDMQTDYSC 207
D+ DYSC
Sbjct: 636 QTWSGDI-GDYSC 647
Score = 34.7 bits (78), Expect = 0.56
Identities = 30/111 (27%), Positives = 44/111 (39%), Gaps = 6/111 (5%)
Query: 942 VPSAPRRFRVRQPNLE---TINLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVENFSP 998
+P +P+ V PN + L W P N ++ Y ++ N K + N P
Sbjct: 667 LPHSPQNLLV-SPNSSHSHAVVLSWVRPFDGNSPILYYIVELSENNSP--WKVHLSNVGP 723
Query: 999 NQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESPAPPNEATPTAAYTN 1049
T TV P Y+F + A +VG G+ E S E P+A N
Sbjct: 724 EMTGVTVSGLTPARTYQFRVCAVNEVGRGQYSAETSRLMLPEEPPSAPPKN 774
>gi|28373126 contactin 4 isoform c precursor [Homo sapiens]
Length = 698
Score = 256 bits (653), Expect = 1e-67
Identities = 187/618 (30%), Positives = 286/618 (46%), Gaps = 54/618 (8%)
Query: 369 CRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYL 428
C+ANG PKPT +W+ NGEPL + ++ T+ +S +YQC N+HG +
Sbjct: 9 CKANGRPKPTYKWLKNGEPLLT---RDRIQIEQGTLNITIVNLSDAGMYQCLAENKHGVI 65
Query: 429 LANAFVSVLDVPP---RMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLD 485
+NA +SV+ V P R L R L++V ++C SP P W K G+ +
Sbjct: 66 FSNAELSVIAVGPDFSRTLLKRVTLVKV--GGEVVIECKPKASPKPVYTW-KKGRDILKE 122
Query: 486 GGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVAR 545
+ E+G+L I + K D G YTC+ATN G A + L VKDPTR+ P
Sbjct: 123 NERITISEDGNLRIINVTKSDAGSYTCIATNHFGTASSTGNLVVKDPTRVMVPPSSMDVT 182
Query: 546 RGTTVQLECRVKHDPSLKLTVSW------LKDDEPLYIGNRMKKEDDS--LTIFGVAERD 597
G ++ L C+V HD SL + +W + D R+ +D + L I + +
Sbjct: 183 VGESIVLPCQVTHDHSLDIVFTWSFNGHLIDFDRDGDHFERVGGQDSAGDLMIRNIQLKH 242
Query: 598 QGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERSVRL 657
G Y C+ T +D+ A A L V +G P P + + ++ + + +L
Sbjct: 243 AGKYVCMVQTSVDRLSAAADLIV---------------RGPPGPPEAVTIDEITDTTAQL 287
Query: 658 TWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVN-----SAVLRLSPYVNYQFR 712
+W PG N+SPIT YV+Q F G W S P ++ + V+ L+P+V Y+FR
Sbjct: 288 SWRPGPDNHSPITMYVIQ-ARTPFSVG-WQAVSTVPELIDGKTFTATVVGLNPWVEYEFR 345
Query: 713 VIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNL 772
+A N +G PS PSE+ RT A PE P +V G G K+ + ITW + G
Sbjct: 346 TVAANVIGIGEPSRPSEKRRTEEALPEVTPANVSGGGGSKSELVITWETVPEELQNGRGF 405
Query: 773 RYIVKWRRRETREAWNNVTVW----GSRYVVGQTPV--YVPYEIRVQAENDFGKGPEPES 826
Y+V + R + W +TV SRYV V + P+E++V N+ G+GP +
Sbjct: 406 GYVVAF-RPYGKMIW-MLTVLASADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPT 463
Query: 827 VIGYSGEDYPRAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNL 886
+ YS E+ P P + R +++T I + W +G+++ Y YWR +N
Sbjct: 464 TVVYSAEEEPTKPPASIFARSLSATDIEVFWASPLEKN-RGRIQGYEVKYWRHEDKEEN- 521
Query: 887 WVSQKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSETKEFTTPEGVPSAP 946
++ G++ ++ L Y L + N G GP S T TT + PS P
Sbjct: 522 -----ARKIRTVGNQTSTKITNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQP 576
Query: 947 RRFRVRQPNLETINLEWD 964
+ + I L WD
Sbjct: 577 PGNIIWNSSDSKIILNWD 594
Score = 84.3 bits (207), Expect = 6e-16
Identities = 151/697 (21%), Positives = 254/697 (36%), Gaps = 89/697 (12%)
Query: 278 ECIASGVPTPDIAWYKKGGDLPS-DKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSI 336
EC A+G P P W K G L + D+ + E L IT V+ D+G Y CLA NK G I
Sbjct: 8 ECKANGRPKPTYKWLKNGEPLLTRDRIQIEQ--GTLNITIVNLSDAGMYQCLAENKHGVI 65
Query: 337 RHTISVRVKAAPYWLDE---PKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPP 393
+ V A + ++ G + + C+ +PKP W G +
Sbjct: 66 FSNAELSVIAVGPDFSRTLLKRVTLVKVGGEVVIECKPKASPKPVYTWK-KGRDILKENE 124
Query: 394 NPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRV 453
G+ I T+ S Y C +N G + + V D P R++ P + + V
Sbjct: 125 RITISEDGNLRIINVTK-SDAGSYTCIATNHFGTASSTGNLVVKD-PTRVMVPPSSM-DV 181
Query: 454 ILYNRTRLDCPFF--GSPIPTLRWFKNGQGSNLDGGNYHVY------ENGSLEIKMIRKE 505
+ L C S W NG + D H G L I+ I+ +
Sbjct: 182 TVGESIVLPCQVTHDHSLDIVFTWSFNGHLIDFDRDGDHFERVGGQDSAGDLMIRNIQLK 241
Query: 506 DQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPE----DQVARRGTTVQLECRVKHDPS 561
G Y C+ + + L V+ P PE D++ TT QL R D
Sbjct: 242 HAGKYVCMVQTSVDRLSAAADLIVRGPP---GPPEAVTIDEIT--DTTAQLSWRPGPDNH 296
Query: 562 LKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVL 621
+T+ ++ P +G + + V E G L+ + + TV
Sbjct: 297 SPITMYVIQARTPFSVGWQ--------AVSTVPELIDGKTFTATVVGLNPWVEYEFRTVA 348
Query: 622 ADQATPTNRLAALPKGRPDRPRDLELTDLA---------------ERSVRLTW--IPGDA 664
A+ + G P RP + T+ A + + +TW +P +
Sbjct: 349 AN---------VIGIGEPSRPSEKRRTEEALPEVTPANVSGGGGSKSELVITWETVPEEL 399
Query: 665 NNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLR---LSPYVNYQFRVIAINEVGS 721
N YVV F + +W + V R + P+ ++ +V N G
Sbjct: 400 QNGRGFGYVVAFR--PYGKMIWMLTVLASADASRYVFRNESVHPFSPFEVKVGVFNNKGE 457
Query: 722 SHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITW-TPM--NATSAFGPNLRYIVKW 778
P P+ ++ P P + ++E+ W +P+ N G ++Y W
Sbjct: 458 G-PFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWASPLEKNRGRIQGYEVKY---W 513
Query: 779 RRRETREAWNNVTVWGSRYVVGQTPV--YVPYEIRVQAENDFGKGPEPESVIGYSGEDYP 836
R + E + G++ T + V Y + V+A N G GP +V + + P
Sbjct: 514 RHEDKEENARKIRTVGNQTSTKITNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPP 573
Query: 837 RAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYY-WRESSLLKNLWVSQKRQQA 895
P + + + + I L W++V + + +++ Y+ Y W S + ++ +
Sbjct: 574 SQPPGNI-IWNSSDSKIILNWDQVKALDNESEVKGYKVLYRWNRQSSTSVIETNKTSVEL 632
Query: 896 SFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSE 932
S P D +Y +E+ + GDG SE
Sbjct: 633 SLPFD------------EDYIIEIKPFSDGGDGSSSE 657
Score = 63.9 bits (154), Expect = 9e-10
Identities = 72/308 (23%), Positives = 119/308 (38%), Gaps = 51/308 (16%)
Query: 51 DNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEY 110
+N+ EC+A G P P++ W +N + R+ + + + + I S G Y
Sbjct: 3 ENVFWECKANGRPKPTYKWLKNGE--PLLTRDRIQIEQGTLNITIVNLSDA------GMY 54
Query: 111 QCFARNKFGTALSNRIRLQVSKSPLWPKENLDPV-VVQEGAPLTLQCNPPPGLPSPVIFW 169
QC A NK G SN ++ P + + L V +V+ G + ++C P P PV W
Sbjct: 55 QCLAENKHGVIFSNAELSVIAVGPDFSRTLLKRVTLVKVGGEVVIECKPKAS-PKPVYTW 113
Query: 170 MSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLT 229
+ + +++R++ +G+L NV D + Y+C + T
Sbjct: 114 -KKGRDILKENERITISEDGNLRIINVTKSDAGS-YTC-------------------IAT 152
Query: 230 NHPYNDSSLRNHPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDI 289
NH SS N V + M P SS V G ++L C + + DI
Sbjct: 153 NHFGTASSTGNL--------VVKDPTRVMVP---PSSMDVTVGESIVLPCQVTHDHSLDI 201
Query: 290 --AWYKKGG--DLPSDKAKFENFNKA-----LRITNVSEEDSGEYFCLASNKMGSIRHTI 340
W G D D FE L I N+ + +G+Y C+ + +
Sbjct: 202 VFTWSFNGHLIDFDRDGDHFERVGGQDSAGDLMIRNIQLKHAGKYVCMVQTSVDRLSAAA 261
Query: 341 SVRVKAAP 348
+ V+ P
Sbjct: 262 DLIVRGPP 269
Score = 53.9 bits (128), Expect = 9e-07
Identities = 47/182 (25%), Positives = 80/182 (43%), Gaps = 11/182 (6%)
Query: 268 MVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFE-NFNKALRITNVSEEDSGEYF 326
+V G ++++EC P P W KKG D+ + + + + LRI NV++ D+G Y
Sbjct: 90 LVKVGGEVVIECKPKASPKPVYTW-KKGRDILKENERITISEDGNLRIINVTKSDAGSYT 148
Query: 327 CLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTV--QWMVN 384
C+A+N G+ T ++ VK + P ++ + GE L C+ + + W N
Sbjct: 149 CIATNHFGTASSTGNLVVKDPTRVMVPPSSMDVTVGESIVLPCQVTHDHSLDIVFTWSFN 208
Query: 385 GEPLQSAPPNPN------REVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLD 438
G + + ++ AGD +I R+ Q+ Y C L A A + V
Sbjct: 209 GHLIDFDRDGDHFERVGGQDSAGDLMI-RNIQLKHAGKYVCMVQTSVDRLSAAADLIVRG 267
Query: 439 VP 440
P
Sbjct: 268 PP 269
>gi|222352127 sidekick 2 [Homo sapiens]
Length = 2172
Score = 234 bits (597), Expect = 4e-61
Identities = 247/1020 (24%), Positives = 402/1020 (39%), Gaps = 93/1020 (9%)
Query: 51 DNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEY 110
+ +++ C A+G+ F W N+R + S+ R +D + G Y
Sbjct: 42 NRLVLTCMAEGSWPLEFKWLHNNRELT-----KFSLEYRYMITSLD-------RTHAGFY 89
Query: 111 QCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWM 170
+C RN+ G L + +QV+ + +E V G ++ P P + W
Sbjct: 90 RCIVRNRMGALLQRQTEVQVAYMGSF-EEGEKHQSVSHGEAAVIRAPRIASFPQPQVTWF 148
Query: 171 SSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKN-------PF 223
+ I R++ L + + D A ++ + KN P
Sbjct: 149 RDGRK-IPPSSRIAITLENTLVILSTVAPD--------AGRYYVQAVNDKNGDNKTSQPI 199
Query: 224 TLKVLTNHPYNDSSLRNHPDMYSARGVAER-TPSFMYPQGTASSQMVLRGMDLLLECIAS 282
TL V + G A+ P+ + P S +V ++ LEC+A+
Sbjct: 200 TLTV-----------------ENVGGPADPIAPTIIIPPKNTS--VVAGTSEVTLECVAN 240
Query: 283 GVPTPD--IAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFC---LASNKMGSIR 337
P I W KK G L S + N+ L I N + D+G Y C L S+ + S+
Sbjct: 241 ARPLIKLHIIW-KKDGVLLS--GGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVV 297
Query: 338 HTISVRVKAAPYWLDEPKNLILAPGEDG-RLVCRANGNPKPTVQWMVNGEPLQSAPPNPN 396
+ V P ++ EP+ I A E + C+A G P P++ W + ++
Sbjct: 298 RGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRF 357
Query: 397 REVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILY 456
R+ + ++QC N G + + +++V + P + R L ++
Sbjct: 358 RQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNIT--RGPLDSTVID 415
Query: 457 NRTR-LDCPFFGSPIPTLRWFKNGQ---GSNLDGGNYHVYENGSLEIKMIRKEDQGIYTC 512
+ L C G+P P + W K + ++ + E+GSL I D G YTC
Sbjct: 416 GMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTC 475
Query: 513 VATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDD 572
+ATN G E L V TRI + P+DQ +GT + C V HDP + + W KD
Sbjct: 476 LATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDG 535
Query: 573 EPLYIGNRMK---KEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTN 629
L + + + SL I D G+YTC + D A+L
Sbjct: 536 ATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHL----------- 584
Query: 630 RLAALPKGRPDRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDH 689
R+ LP P+ P L+ + R++ LTW NSP+ Y+++ E+ P
Sbjct: 585 RVRQLPHA-PEHP-VATLSTVERRAINLTWTKPFDGNSPLIRYILEMSENN-APWTVLLA 641
Query: 690 SKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEG 749
S P + + V L P +YQFR+ A+N+VG S +ER PP + P +V G
Sbjct: 642 SVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASG 701
Query: 750 TRKNNMEITWTPMNATSAFGPNLRYIVKW--RRRETREAWNNVT-VWGSRYVVGQTPVYV 806
++ I W P + G YI+++ + N+T + ++ ++
Sbjct: 702 RTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWT 761
Query: 807 PYEIRVQAENDFGKGPEPESVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWNRVYSDTVQ 866
YEI V A N G G V ++ + P P V NST I WN +
Sbjct: 762 NYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFIN 821
Query: 867 GQLREYRAYYWRESSLLKNLWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRG 926
G + Y+ W + V+ + +F G VS L ++ Y ++ G
Sbjct: 822 GINQGYKLIAWEPE---QEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPG 878
Query: 927 DGPRSETKEFTTPEGVPSAPRRFRVRQPNLETINLEWDHPEHPNGIMIGYTLKYVAFNGT 986
DGPRS + T E VP + ++ + W P NGI+ GY + + +N T
Sbjct: 879 DGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGILTGYRISWEEYNRT 938
Query: 987 KVGKQIVENFSPNQT-KFTVQRTDPVSRYRFTLSARTQVGSGE--AVTEESPAPPNEATP 1043
V ++ PN T ++ V ++ Y ++A T G G+ A T S PP P
Sbjct: 939 NTR---VTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGP 995
Score = 142 bits (357), Expect = 2e-33
Identities = 111/435 (25%), Positives = 194/435 (44%), Gaps = 27/435 (6%)
Query: 624 QATPTNRLAALPKGRPDRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQP 683
Q + + + +P P P +L ++++ RSV L + PG + I+ ++V+ +
Sbjct: 978 QVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQFRPGYDGKTSISRWLVEAQVGVVGE 1037
Query: 684 GV-W---HDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPE 739
G W H S P + + V L+P+ Y FR+ +N VG+S PS PS + +T APP+
Sbjct: 1038 GEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPD 1097
Query: 740 SNPGDVKGEGTRKNNMEITWTPMNATSAFG--PNLRYIVKWRRRETREAWNNVTVWG--- 794
P +V + ++ + W P+ G ++ Y +K+ R + + V
Sbjct: 1098 MAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVE 1157
Query: 795 SRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDYPRAAPTEVKVRVMNSTAIS 854
Y + + Y ++VQA N G GP ++V+G + E P + PT V S+++
Sbjct: 1158 RDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSML 1217
Query: 855 LQWNRVYSDTVQGQLREYRAYY-WRESSLLKNLWVSQKRQQASFPGDRLRGVVSRLFPYS 913
++W+ V G + Y+ Y ++S W+ + S ++ L Y
Sbjct: 1218 VRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRS-------AQLTGLGKYV 1270
Query: 914 NYKLEMVVVNGRGDGPRSETKEF-TTPEGVPSAPRRFRVRQPNLETINLEWDHPEHPNGI 972
Y+++++ GDG S T + VP P + ++ L W P PNGI
Sbjct: 1271 LYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGI 1330
Query: 973 MIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEA--- 1029
++ Y + + N T VE +P+ ++T P S Y F ++A+T+ G GEA
Sbjct: 1331 ILAYQITH-RLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEA 1389
Query: 1030 --VTEES---PAPPN 1039
VT E P PP+
Sbjct: 1390 LVVTTEKRDRPQPPS 1404
Score = 137 bits (345), Expect = 6e-32
Identities = 117/440 (26%), Positives = 182/440 (41%), Gaps = 52/440 (11%)
Query: 639 PDRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNS 698
P RP ++ D+ RSV L+W PG SP+ Y +Q E G W HS S
Sbjct: 1403 PSRPM-VQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTRE--LPSGRWALHSASVSHNAS 1459
Query: 699 AVL--RLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNME 756
+ + RL P+ +Y+FRV A N++G S S SE T A P+ P + ++
Sbjct: 1460 SFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVL 1519
Query: 757 ITWTPMNATSAFGPNLRYIVKWR-------RRETREAWNNV-TVWG-------------- 794
I W P G L + +++R R T NN W
Sbjct: 1520 IRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRP 1579
Query: 795 --SRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDYPRAAPTEVKVRVMNSTA 852
++Y + + YEIR+ N G+GP + GE P AAP V V +T
Sbjct: 1580 SLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQ 1639
Query: 853 ISLQWNRVYSDTVQGQLREYRAYYWRE-----SSLLKNLWVSQKRQQASFPGDRLRGVVS 907
+ + W D+ G ++ Y+ Y+W + +K L++++ + +
Sbjct: 1640 LDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVK-----------LK 1688
Query: 908 RLFPYSNYKLEMVVVNGRGDGPRSETKEFTTPEGVPSAPRRFRVRQPNLETINLEWDHPE 967
L Y+ Y + + N GDGPRS + T + PSAP + + ++N+ W+ P+
Sbjct: 1689 NLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQ 1748
Query: 968 HPNGIMIGYTLKYVAFNG----TKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQ 1023
PNGI+ GY L Y + +K+ V+ SP K V+ YRF + A+T
Sbjct: 1749 FPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLK--VKDLAEGVTYRFRIRAKT- 1805
Query: 1024 VGSGEAVTEESPAPPNEATP 1043
G + P E P
Sbjct: 1806 FTYGPEIEANVTTGPGEGAP 1825
Score = 67.0 bits (162), Expect = 1e-10
Identities = 78/334 (23%), Positives = 127/334 (38%), Gaps = 47/334 (14%)
Query: 29 MDLTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRR 88
+ + +PP K+ + + + I C+AKG P PS W +++ + K R R
Sbjct: 302 LSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRN 361
Query: 89 RSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQE 148
G + SG P++ G +QCFARN G ++ S +P + LD V+ +
Sbjct: 362 DGGLQI----SGLVPDD-TGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVI-D 415
Query: 149 GAPLTLQCNPPPGLPSPVIFWMSSS---MEPITQDKRVSQGHNGDLYFSNVMLQDMQTDY 205
G + L C G P P I W Q R + +G L S + D T Y
Sbjct: 416 GMSVVLACE-TSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGT-Y 473
Query: 206 SCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRNHPDMYSARGVAERTPSFMYPQGTAS 265
+C A ++ R + + V RT PQ
Sbjct: 474 TCLA--------------------------TNSRGVDEASADLVVWARTRITKPPQ---- 503
Query: 266 SQMVLRGMDLLLECIASGVPTPDI--AWYKKGGDLPSD---KAKFENFNKALRITNVSEE 320
Q V++G + C + P I W K G L ++ + + + N +L I+
Sbjct: 504 DQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDR-NGSLHISQTWSG 562
Query: 321 DSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEP 354
D G Y C + G+ + +RV+ P+ + P
Sbjct: 563 DIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHP 596
Score = 64.7 bits (156), Expect = 5e-10
Identities = 82/375 (21%), Positives = 136/375 (36%), Gaps = 32/375 (8%)
Query: 266 SQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEY 325
+Q+ L G L+L C+A G + W +L ++ IT++ +G Y
Sbjct: 35 TQVHLEGNRLVLTCMAEGSWPLEFKWLHNNRELTKFSLEYRYM-----ITSLDRTHAGFY 89
Query: 326 FCLASNKMGS-IRHTISVRVKAAPYWLDEPKNLILAPGEDGRL-VCRANGNPKPTVQWMV 383
C+ N+MG+ ++ V+V + + K+ ++ GE + R P+P V W
Sbjct: 90 RCIVRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGEAAVIRAPRIASFPQPQVTWFR 149
Query: 384 NGEPLQSAPPNPNREVA-GDTIIFRDTQISSRAVYQCNTSNEHG----------YLLANA 432
+G + PP+ + +T++ T Y N+ + N
Sbjct: 150 DGRKI---PPSSRIAITLENTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTVENV 206
Query: 433 FVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVY 492
+ P ++ P V + L+C P+ L G L GG
Sbjct: 207 GGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLSGGISD-- 264
Query: 493 ENGSLEIKMIRKEDQGIYTCVATNILGKAENQVR---LEVKDPTRIYRMPEDQV-ARRGT 548
N L I D G Y C A + VR L V +P + + PE + A
Sbjct: 265 HNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEK 324
Query: 549 TVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMK---KEDDSLTIFGVAERDQGSYTCVA 605
V + C+ K P +T W KD + + + + D L I G+ D G + C A
Sbjct: 325 VVDIPCQAKGVPPPSIT--WYKDAAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFA 382
Query: 606 STELDQDLAKAYLTV 620
+ YL V
Sbjct: 383 RNAAGEVQTSTYLAV 397
Score = 59.7 bits (143), Expect = 2e-08
Identities = 89/433 (20%), Positives = 164/433 (37%), Gaps = 22/433 (5%)
Query: 627 PTNRLAALPKGRPDRPRDLELTDLAERSVRLTWIP---GDANNSPIT-DYVVQFEEDQFQ 682
P+ ++ L P ++ L +E S+ L W+P + N +P + Y +++
Sbjct: 1085 PSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGH 1144
Query: 683 PGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNP 742
+ + + L + Y+ +V A N +GS P + RT + P S P
Sbjct: 1145 GKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSG-PWSQTVVGRTRESVPSSGP 1203
Query: 743 GDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETREAWNNVTVWGSRYVVGQT 802
+V T ++M + W+ + G L Y V ++ +++ V G+ Q
Sbjct: 1204 TNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQL 1263
Query: 803 P---VYVPYEIRVQAENDFGKG-PEPESVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWN 858
YV YE++V A G G P ++ + +D P P + + +T++ L W
Sbjct: 1264 TGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVP-GPPMGILFPEVRTTSVRLIWQ 1322
Query: 859 RVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLE 918
+ G + Y+ + ++ V A + + L P S Y
Sbjct: 1323 PPAAPN--GIILAYQITHRLNTTTANTATVEVLAPSAR------QYTATGLKPESVYLFR 1374
Query: 919 MVVVNGRGDGPRSETKEFTTPE-GVPSAPRRFRVRQPNLE--TINLEWDHPEHPNGIMIG 975
+ +G G +E TT + P P R V+Q ++ ++ L W+ +
Sbjct: 1375 ITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGSDGLSPVRY 1434
Query: 976 YTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESP 1035
YT++ + + S N + F V R P + Y+F + A +G E E
Sbjct: 1435 YTIQTRELPSGRWALHSA-SVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESES 1493
Query: 1036 APPNEATPTAAYT 1048
+A P A T
Sbjct: 1494 LTTLQAAPDEAPT 1506
Score = 49.3 bits (116), Expect = 2e-05
Identities = 30/89 (33%), Positives = 42/89 (47%), Gaps = 6/89 (6%)
Query: 654 SVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWH----DHSKYPGSVNSAVLRLSPYVNY 709
++ + W GD PIT YV++ G+W D K S ++ L P V+Y
Sbjct: 1839 AIAIHWSSGDPGKGPITRYVIEARPSD--EGLWDILIKDIPKEVSSYTFSMDILKPGVSY 1896
Query: 710 QFRVIAINEVGSSHPSLPSERYRTSGAPP 738
FRVIA+N+ G PS PS+ A P
Sbjct: 1897 DFRVIAVNDYGFGTPSSPSQSVPAQKANP 1925
Score = 38.5 bits (88), Expect = 0.039
Identities = 30/107 (28%), Positives = 42/107 (39%), Gaps = 10/107 (9%)
Query: 959 INLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTL 1018
INL W P N +I Y L+ N ++ + P T TV+ P Y+F L
Sbjct: 608 INLTWTKPFDGNSPLIRYILEMSENNAPWT--VLLASVDPKATSVTVKGLVPARSYQFRL 665
Query: 1019 SARTQVGSGE--------AVTEESPAPPNEATPTAAYTNNQADIATQ 1057
A VG G+ ++ EE P P + + TN I Q
Sbjct: 666 CAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQ 712
>gi|157311649 neogenin homolog 1 [Homo sapiens]
Length = 1461
Score = 216 bits (550), Expect = 1e-55
Identities = 207/803 (25%), Positives = 343/803 (42%), Gaps = 64/803 (7%)
Query: 270 LRGMDLLLECIASGVPTPDIAWYKKGG--DLPSDKAKFENFNKALRITNV-----SEEDS 322
+RG ++L C A P+P I W K G +L SD + + +L I+NV ++ D
Sbjct: 65 VRGSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFISNVVHSKHNKPDE 124
Query: 323 GEYFCLAS-NKMGSI-RHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQ 380
G Y C+A+ +G+I T + V P + +P+ + G + L C N + P V+
Sbjct: 125 GYYQCVATVESLGTIISRTAKLIVAGLPRFTSQPEPSSVYAGNNAILNCEVNADLVPFVR 184
Query: 381 WMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVP 440
W N +PL + +G +I T+ +Y+C + ++ +
Sbjct: 185 WEQNRQPLL-LDDRVIKLPSGMLVISNATE-GDGGLYRCVVESGGPPKYSDEVELKVLPD 242
Query: 441 PRMLSPR------NQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVY-E 493
P ++S + L+RVI + L C G P PT++W KN + + + V
Sbjct: 243 PEVISDLVFLKQPSPLVRVIGQDVV-LPCVASGLPTPTIKWMKNEEALDTESSERLVLLA 301
Query: 494 NGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLE 553
GSLEI + ++D G Y C+A N E Q L V+ + P + A + E
Sbjct: 302 GGSLEISDVTEDDAGTYFCIADNGNETIEAQAELTVQAQPEFLKQPTNIYAHESMDIVFE 361
Query: 554 CRVKHDPSLKLTVSWLKDDEPLYIGNRMK-KEDDSLTIFGVAERDQGSYTCVASTELDQD 612
C V P+ TV W+K+ + + + K ++ +L + G+ + D+G Y C+A ++
Sbjct: 362 CEVTGKPTP--TVKWVKNGDMVIPSDYFKIVKEHNLQVLGLVKSDEGFYQCIAENDVGNA 419
Query: 613 LAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERSVRLTWIP--GDANNSPIT 670
A A L +L T L P PRD+ + ++ R ++LTW D + +T
Sbjct: 420 QAGAQLIILEHAPATTGPL-------PSAPRDVVASLVSTRFIKLTWRTPASDPHGDNLT 472
Query: 671 DYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSER 730
V +E + V +++ +PG + + L P Y FRV+A N+ GS S P
Sbjct: 473 YSVFYTKEGIARERV--ENTSHPGEMQVTIQNLMPATVYIFRVMAQNKHGSGESSAP--- 527
Query: 731 YRTSGAPPESNPG---DVKGEGTRKNNMEITW-TPMNATSAF-GPNLRYIVKWRRRETRE 785
R P PG +++ ++ +TW TP++ L Y+ K +E
Sbjct: 528 LRVETQPEVQLPGPAPNLRAYAASPTSITVTWETPVSGNGEIQNYKLYYMEKGTDKE--- 584
Query: 786 AWNNVTVWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDYPRAAPTEVKV 845
+V V Y + Y Y RV A N G G V + D P AAP + +
Sbjct: 585 --QDVDVSSHSYTINGLKKYTEYSFRVVAYNKHGPGVSTPDVAVRTLSDVPSAAPQNLSL 642
Query: 846 RVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQASFPGDRLRGV 905
V NS +I + W T GQ+ Y+ Y R++S ++ + G +L +
Sbjct: 643 EVRNSKSIMIHWQPPAPATQNGQITGYKIRY-RKASRKSDV------TETLVSGTQLSQL 695
Query: 906 VSRLFPYSNYKLEMVVVNGRGDGPRSETKEFTTPEG------VPSAPRRFRVRQPNLETI 959
+ L + Y + + G GP ++ T E VP P VR P + +I
Sbjct: 696 IEGLDRGTEYNFRVAALTINGTGPATDWLSAETFESDLDETRVPEVPSSLHVR-PLVTSI 754
Query: 960 NLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLS 1019
+ W PE+ N ++ GY + Y G+ + I ++ Q +T++ DP S Y TL
Sbjct: 755 VVSWTPPENQNIVVRGYAIGYGI--GSPHAQTIKVDY--KQRYYTIENLDPSSHYVITLK 810
Query: 1020 ARTQVGSGEAVTEESPAPPNEAT 1042
A VG G + E + P+ T
Sbjct: 811 AFNNVGEGIPLYESAVTRPHTDT 833
Score = 161 bits (408), Expect = 3e-39
Identities = 249/1111 (22%), Positives = 425/1111 (38%), Gaps = 153/1111 (13%)
Query: 6 PPPWVHAAFLLCLLSLGGAIEIPMDLTQPP--TITKQSAKDHIVDPRD-------NILIE 56
P W++ LL + G A Q P +I + +V+P D ++++
Sbjct: 14 PSFWLYCLLLLGRRAPGAAAARSGSAPQSPGASIRTFTPFYFLVEPVDTLSVRGSSVILN 73
Query: 57 CEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFAR- 115
C A P+P W ++ F N+ D R + + + + EG YQC A
Sbjct: 74 CSAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFISNVVHSKHNKPDEGYYQCVATV 133
Query: 116 NKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSME 175
GT +S +L V+ P + + +P V G L C L P + W + +
Sbjct: 134 ESLGTIISRTAKLIVAGLPRFTSQP-EPSSVYAGNNAILNCEVNADL-VPFVRW-EQNRQ 190
Query: 176 PITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYND 235
P+ D RV + +G L SN D Y C ++ P Y+D
Sbjct: 191 PLLLDDRVIKLPSGMLVISNATEGDGGL-YRC--------VVESGGP--------PKYSD 233
Query: 236 S-SLRNHPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYK- 293
L+ PD E ++ + + V+ G D++L C+ASG+PTP I W K
Sbjct: 234 EVELKVLPD-------PEVISDLVFLKQPSPLVRVI-GQDVVLPCVASGLPTPTIKWMKN 285
Query: 294 -KGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLD 352
+ D S + +L I++V+E+D+G YFC+A N +I + V+A P +L
Sbjct: 286 EEALDTESSERLVLLAGGSLEISDVTEDDAGTYFCIADNGNETIEAQAELTVQAQPEFLK 345
Query: 353 EPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQIS 412
+P N+ D C G P PTV+W+ NG+ + P + + V + S
Sbjct: 346 QPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMV--IPSDYFKIVKEHNLQVLGLVKS 403
Query: 413 SRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYN-----------RTRL 461
YQC N+ G A A + +L+ P P R ++ + RT
Sbjct: 404 DEGFYQCIAENDVGNAQAGAQLIILEHAPATTGPLPSAPRDVVASLVSTRFIKLTWRTPA 463
Query: 462 DCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKA 521
P + ++ + K G H E + I+ + I+ +A N G
Sbjct: 464 SDPHGDNLTYSVFYTKEGIARERVENTSHPGEM-QVTIQNLMPATVYIFRVMAQNKHGSG 522
Query: 522 ENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSW---------LKDD 572
E+ P R+ PE Q+ G L S +TV+W +++
Sbjct: 523 ESSA------PLRVETQPEVQLP--GPAPNLRAYAASPTS--ITVTWETPVSGNGEIQNY 572
Query: 573 EPLYIGNRMKKEDD------SLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLADQAT 626
+ Y+ KE D S TI G+ + + S+ VA + + +T
Sbjct: 573 KLYYMEKGTDKEQDVDVSSHSYTINGLKKYTEYSFRVVAYNKHGPGV-----------ST 621
Query: 627 PTNRLAALPKGRPDRPRDLELTDLAERSVRLTWIP--GDANNSPITDYVVQFEEDQFQPG 684
P + L P++L L +S+ + W P N IT Y +++ + +
Sbjct: 622 PDVAVRTLSDVPSAAPQNLSLEVRNSKSIMIHWQPPAPATQNGQITGYKIRYRKASRKSD 681
Query: 685 VWHDHSKYPGSVNSAVLR-LSPYVNYQFRVIA--INEVGSSHPSLPSERYRT----SGAP 737
V + G+ S ++ L Y FRV A IN G + L +E + + + P
Sbjct: 682 V--TETLVSGTQLSQLIEGLDRGTEYNFRVAALTINGTGPATDWLSAETFESDLDETRVP 739
Query: 738 PESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETREAWNNVTVWGSRY 797
+ V+ T ++ ++WTP + Y + + V Y
Sbjct: 740 EVPSSLHVRPLVT---SIVVSWTPPENQNIVVRG--YAIGYGIGSPHAQTIKVDYKQRYY 794
Query: 798 VVGQTPVYVPYEIRVQAENDFGKG-PEPESVIGYSGEDYPRAAPTEVKVRVMNS------ 850
+ Y I ++A N+ G+G P ES + P +EV + V+N+
Sbjct: 795 TIENLDPSSHYVITLKAFNNVGEGIPLYESAV-----TRPHTDTSEVDLFVINAPYTPVP 849
Query: 851 ------TAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQ-----QASFPG 899
+ +Q + + DT++ W ++SL K+ ++ R + + P
Sbjct: 850 DPTPMMPPVGVQASILSHDTIR--------ITWADNSLPKHQKITDSRYYTVRWKTNIPA 901
Query: 900 D---------RLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSETKEFTTPEGVPSAPRR-- 948
+ L +V+ L P + Y+ ++V GR S T TT E VP++P +
Sbjct: 902 NTKYKNANATTLSYLVTGLKPNTLYEFSVMVTKGRRSSTWSMTAHGTTFELVPTSPPKDV 961
Query: 949 -FRVRQPNLETINLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQR 1007
++ +TI + W P NG + GY + Y ++ ++E N+ +Q
Sbjct: 962 TVVSKEGKPKTIIVNWQPPSEANGKITGYIIYYSTDVNAEIHDWVIEPVVGNRLTHQIQE 1021
Query: 1008 TDPVSRYRFTLSARTQVGSG---EAVTEESP 1035
+ Y F + AR G G EAV +P
Sbjct: 1022 LTLDTPYYFKIQARNSKGMGPMSEAVQFRTP 1052
Score = 40.0 bits (92), Expect = 0.013
Identities = 66/329 (20%), Positives = 111/329 (33%), Gaps = 41/329 (12%)
Query: 639 PDRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSK-----YP 693
P+ P L + L S+ ++W P + N + Y + + G+ H++ Y
Sbjct: 739 PEVPSSLHVRPLVT-SIVVSWTPPENQNIVVRGYAIGY-------GIGSPHAQTIKVDYK 790
Query: 694 GSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTS-----------GAP----- 737
+ + L P +Y + A N VG P S R AP
Sbjct: 791 QRYYT-IENLDPSSHYVITLKAFNNVGEGIPLYESAVTRPHTDTSEVDLFVINAPYTPVP 849
Query: 738 ---PESNPGDVKGEGTRKNNMEITWTPMNATS--AFGPNLRYIVKWRRR-ETREAWNNVT 791
P P V+ + + ITW + + Y V+W+ + N
Sbjct: 850 DPTPMMPPVGVQASILSHDTIRITWADNSLPKHQKITDSRYYTVRWKTNIPANTKYKNAN 909
Query: 792 VWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDYPRAAPTEVKVRVMNST 851
Y+V YE V + G + E P + P +V V
Sbjct: 910 ATTLSYLVTGLKPNTLYEFSVMVTKGRRSSTWSMTAHGTTFELVPTSPPKDVTVVSKEGK 969
Query: 852 AISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQASFPGDRLRGVVSRLFP 911
++ N G++ Y YY + + + WV + G+RL + L
Sbjct: 970 PKTIIVNWQPPSEANGKITGYIIYYSTDVNAEIHDWVIEP-----VVGNRLTHQIQELTL 1024
Query: 912 YSNYKLEMVVVNGRGDGPRSETKEFTTPE 940
+ Y ++ N +G GP SE +F TP+
Sbjct: 1025 DTPYYFKIQARNSKGMGPMSEAVQFRTPK 1053
>gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42
precursor [Homo sapiens]
Length = 2012
Score = 209 bits (533), Expect = 1e-53
Identities = 259/1049 (24%), Positives = 412/1049 (39%), Gaps = 148/1049 (14%)
Query: 36 TITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVI 95
TI+ + K + + + C G W RN N K+ R++ L++
Sbjct: 317 TISPRKVKSSV---GSQVSLSCSVTGTEDQELSWYRNGEILNPGKNVRITGINHEN-LIM 372
Query: 96 DF--RSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPK--ENLDPVVVQEGAP 151
D +S G G YQCF R LS + +QV PK VV P
Sbjct: 373 DHMVKSDG------GAYQCFVRKD---KLSAQDYVQVVLEDGTPKIISAFSEKVVSPAEP 423
Query: 152 LTLQCNPPPGLPSPVIFWMSSSMEPITQ--DKRVSQ---GHNGDLYFSNVMLQDMQTD-- 204
++L CN G P P I W +PI + R+SQ + + N+ ++
Sbjct: 424 VSLMCNVK-GTPLPTITWTLDD-DPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGV 481
Query: 205 YSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRNHPDMYSARGVAERTPSFMYPQGTA 264
Y C A N + + +Y AR + R P+ + P
Sbjct: 482 YRCTAN-----------------------NSAGVV----LYQAR-INVRGPASIRPMKNI 513
Query: 265 SSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSD--KAKFENFNKALRITNVSEE-D 321
++ + G D + C G P I WYK LP + + FEN N L++++V +E D
Sbjct: 514 TA---IAGRDTYIHCRVIGYPYYSIKWYKNSNLLPFNHRQVAFEN-NGTLKLSDVQKEVD 569
Query: 322 SGEYFC-LASNKMGSIRHTISVRVKAAPYW--LDEPKNLILAPGEDGRLVCRANGNPKP- 377
GEY C + S ++ V VK P+ + P+ I G+ + C P
Sbjct: 570 EGEYTCNVLVQPQLSTSQSVHVTVKVPPFIQPFEFPRFSI---GQRVFIPCVVVSGDLPI 626
Query: 378 TVQWMVNGEPLQSAPPNPNREVAGDTIIFRDT-QISSRAV-----YQCNTSNEHGYLLAN 431
T+ W +G P+ + V D I F + +IS+ ++ Y C NE +
Sbjct: 627 TITWQKDGRPIPGS-----LGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQ 681
Query: 432 AFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLD------ 485
+ + V P ++ PR+Q I L+C G P+PT+ W K +G+ +
Sbjct: 682 SQLIVRVPPKFVVQPRDQ--DGIYGKAVILNCSAEGYPVPTIVW-KFSKGAGVPQFQPIA 738
Query: 486 -GGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGK-AENQVRLEVKDPTRIYRMPEDQV 543
G V NGSL IK + +ED G Y C +N +G + L VK P I P +
Sbjct: 739 LNGRIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTVKIPAMITSYPNTTL 798
Query: 544 ARRGTTVQLECRVKHDPSLKLTVSWLKDDEPL------YIGNRMKKEDD---SLTIFGVA 594
A +G ++ C + + V W K+D + Y+ + + ++ +L I
Sbjct: 799 ATQGQKKEMSCTAHGEKPI--IVRWEKEDRIINPEMARYLVSTKEVGEEVISTLQILPTV 856
Query: 595 ERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERS 654
D G ++C A +D LTV P P ++E+ D+ R+
Sbjct: 857 REDSGFFSCHAINSYGEDRGIIQLTVQ----------------EPPDPPEIEIKDVKART 900
Query: 655 VRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSA-VLRLSPYVNYQFRV 713
+ L W G NSPIT Y ++ + +NSA ++ + P Y R+
Sbjct: 901 ITLRWTMGFDGNSPITGYDIECKNKSDSWDSAQRTKDVSPQLNSATIIDIHPSSTYSIRM 960
Query: 714 IAINEVGSSHPSLPSERYRTSG-APPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNL 772
A N +G S PS +E T+ A P+ P +V E ++ +TW G
Sbjct: 961 YAKNRIGKSEPS--NELTITADEAAPDGPPQEVHLEPISSQSIRVTWKAPKKHLQNGIIR 1018
Query: 773 RYIVKWRRRET--REAWNNVTVWGSR----YVVGQTPVYVPYEIRVQAENDFGKGPEPES 826
Y + +R T +N ++V S Y + + Y + VQA N G GP +
Sbjct: 1019 GYQIGYREYSTGGNFQFNIISVDTSGDSEVYTLDNLNKFTQYGLVVQACNRAGTGPSSQE 1078
Query: 827 VIGYSGEDYPRAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWR-----ESS 881
+I + ED P P V+ + +IS+ W+ + + + G L+ +R YW E
Sbjct: 1079 IITTTLEDVPSYPPENVQAIATSPESISISWSTLSKEALNGILQGFRVIYWANLMDGELG 1138
Query: 882 LLKNLWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSETKEFTTPEG 941
+KN+ +Q P L G L Y+NY ++++ GDG RSE T E
Sbjct: 1139 EIKNITTTQ-------PSLELDG----LEKYTNYSIQVLAFTRAGDGVRSEQIFTRTKED 1187
Query: 942 VPSAPRRFRVRQPNLETINLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVE-NFSPNQ 1000
VP P + + + + W P NGI+ KY F I E SP+
Sbjct: 1188 VPGPPAGVKAAAASASMVFVSWLPPLKLNGII----RKYTVFCSHPYPTVISEFEASPDS 1243
Query: 1001 TKFTVQRTDPVSRYRFTLSARTQVGSGEA 1029
+ + +Y + A T G G +
Sbjct: 1244 FSYRIPNLSRNRQYSVWVVAVTSAGRGNS 1272
Score = 141 bits (355), Expect = 4e-33
Identities = 188/881 (21%), Positives = 332/881 (37%), Gaps = 105/881 (11%)
Query: 19 LSLGGAIEIPMDLTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNI 78
LS +++ ++ P I+ S K +V P + + + C KG P P+ WT +
Sbjct: 392 LSAQDYVQVVLEDGTPKIISAFSEK--VVSPAEPVSLMCNVKGTPLPTITWTLDDDPILK 449
Query: 79 AKDPRVSMRRRSGTLVIDFRSGGRPEEYEGE-YQCFARNKFGTALSN-RIRLQVSKSPLW 136
R+S S V+ + + + +G Y+C A N G L RI ++ S +
Sbjct: 450 GGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGPAS-IR 508
Query: 137 PKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNV 196
P +N+ + G + C G P I W +S ++V+ +NG L S+V
Sbjct: 509 PMKNITAIA---GRDTYIHCRVI-GYPYYSIKWYKNSNLLPFNHRQVAFENNGTLKLSDV 564
Query: 197 MLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRNHPDMYSARGVAERTPS 256
+ + +Y+CN + Q T+KV P
Sbjct: 565 QKEVDEGEYTCNVLVQPQLSTSQSVHVTVKV---------------------------PP 597
Query: 257 FMYPQGTASSQMVLRGMDLLLECIASGVPTP-DIAWYKKGGDLPSDKA-KFEN--FNKAL 312
F+ P + G + + C+ P I W K G +P +N F +L
Sbjct: 598 FIQPFEFPRFSI---GQRVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSL 654
Query: 313 RITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRAN 372
RI+N+S +G Y C+A N+ ++ H + V+ P ++ +P++ G+ L C A
Sbjct: 655 RISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQPRDQDGIYGKAVILNCSAE 714
Query: 373 GNPKPTVQWMVN---GEPLQSAPPNPNREV---AGDTIIFRDTQISSRAVYQCNTSNEHG 426
G P PT+ W + G P Q P N + + +++ + Y C SN+ G
Sbjct: 715 GYPVPTIVWKFSKGAGVP-QFQPIALNGRIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVG 773
Query: 427 YLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDG 486
++ + + +P + S N + + + C G +RW K + N +
Sbjct: 774 ADVSKSMYLTVKIPAMITSYPNTTL-ATQGQKKEMSCTAHGEKPIIVRWEKEDRIINPEM 832
Query: 487 GNYHVYEN-------GSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMP 539
Y V +L+I +ED G ++C A N G+ ++L V++P +
Sbjct: 833 ARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPPDPPEIE 892
Query: 540 EDQVARRGTTVQ---------------LECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKE 584
V R T++ +EC+ K D SW + ++
Sbjct: 893 IKDVKARTITLRWTMGFDGNSPITGYDIECKNKSD-------SWDSAQRTKDVSPQL--- 942
Query: 585 DDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRD 644
+S TI + S A + + LT+ AD+A P P++
Sbjct: 943 -NSATIIDIHPSSTYSIRMYAKNRIGKSEPSNELTITADEAAPDG-----------PPQE 990
Query: 645 LELTDLAERSVRLTWIPGDAN--NSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVL- 701
+ L ++ +S+R+TW + N I Y + + E + S +S V
Sbjct: 991 VHLEPISSQSIRVTWKAPKKHLQNGIIRGYQIGYREYSTGGNFQFNIISVDTSGDSEVYT 1050
Query: 702 --RLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITW 759
L+ + Y V A N G+ PS T P P +V+ T ++ I+W
Sbjct: 1051 LDNLNKFTQYGLVVQACNRAGTG-PSSQEIITTTLEDVPSYPPENVQAIATSPESISISW 1109
Query: 760 TPMNATSAFGPNLRY-IVKWRRRETREAW--NNVTVWGSRYVVGQTPVYVPYEIRVQAEN 816
+ ++ + G + ++ W E N+T + Y Y I+V A
Sbjct: 1110 STLSKEALNGILQGFRVIYWANLMDGELGEIKNITTTQPSLELDGLEKYTNYSIQVLAFT 1169
Query: 817 DFGKGPEPESVIGYSGEDYPRAAPTEVKVRVMNSTAISLQW 857
G G E + + ED P P VK +++ + + W
Sbjct: 1170 RAGDGVRSEQIFTRTKEDVP-GPPAGVKAAAASASMVFVSW 1209
Score = 113 bits (282), Expect = 1e-24
Identities = 135/573 (23%), Positives = 220/573 (38%), Gaps = 63/573 (10%)
Query: 54 LIECEAKGNPAPSFHW--TRNSRFFNIAKDPRVSMRRRSGTL-VIDFR-SGGRPEEYEGE 109
L+ C A G P + W +++ P + +GTL + F S ++
Sbjct: 43 LVPCPAAGIPPVTLRWYLATGEEIYDV---PGIRHVHPNGTLQIFPFPPSSFSTLIHDNT 99
Query: 110 YQCFARNKFGTALSNRIRLQ-VSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPS--PV 166
Y C A N G S + ++ V + P + ++ G +C P + + V
Sbjct: 100 YYCTAENPSGKIRSQDVHIKAVLREPYTVR--VEDQKTMRGNVAVFKCIIPSSVEAYITV 157
Query: 167 IFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLK 226
+ W ++ + R G LY +V +D +Y C R +T +Q N + +
Sbjct: 158 VSWEKDTVS-LVSGSRFLITSTGALYIKDVQNEDGLYNYRCITRHRYTGETRQSN--SAR 214
Query: 227 VLTNHPYNDSSLRNHPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPT 286
+ + P N + PS + + + G + L C A G P
Sbjct: 215 LFVSDPANSA------------------PSIL---DGFDHRKAMAGQRVELPCKALGHPE 253
Query: 287 PDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKA 346
PD W K L +F+ L I N+ DSG Y C SN+ G+ + + VK
Sbjct: 254 PDYRWLKDNMPLELS-GRFQKTVTGLLIENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQ 312
Query: 347 APYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAG---DT 403
P+ + + G L C G + W NGE L P N + G +
Sbjct: 313 PLKATISPRKVKSSVGSQVSLSCSVTGTEDQELSWYRNGEILN---PGKNVRITGINHEN 369
Query: 404 IIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVL--DVPPRMLSPRNQLIRVILYNRTRL 461
+I S YQC + L A +V V+ D P+++S ++ + V L
Sbjct: 370 LIMDHMVKSDGGAYQCFVRKDK--LSAQDYVQVVLEDGTPKIISAFSEKV-VSPAEPVSL 426
Query: 462 DCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYEN--------GSLEIKMIRKEDQGIYTCV 513
C G+P+PT+ W + L GG++ + + L I + D G+Y C
Sbjct: 427 MCNVKGTPLPTITWTLD-DDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCT 485
Query: 514 ATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDE 573
A N G Q R+ V+ P I R ++ A G + CRV P ++ W K+
Sbjct: 486 ANNSAGVVLYQARINVRGPASI-RPMKNITAIAGRDTYIHCRVIGYP--YYSIKWYKNSN 542
Query: 574 PLYIGNRMK--KEDDSLTIFGV-AERDQGSYTC 603
L +R + + +L + V E D+G YTC
Sbjct: 543 LLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTC 575
Score = 60.1 bits (144), Expect = 1e-08
Identities = 75/303 (24%), Positives = 119/303 (39%), Gaps = 34/303 (11%)
Query: 328 LASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLV-CRANGNPKPTVQW-MVNG 385
LA + S + S + ++ Y+++ ++ G LV C A G P T++W + G
Sbjct: 4 LALSLFQSFANVFSEDLHSSLYFVNASLQEVVFASTTGTLVPCPAAGIPPVTLRWYLATG 63
Query: 386 EPLQSAPPNPNREVAGDTIIFRDTQISSRAV-----YQCNTSNEHGYLLANAFVSVLDVP 440
E + P + G IF S + Y C N G + + DV
Sbjct: 64 EEIYDVPGIRHVHPNGTLQIFPFPPSSFSTLIHDNTYYCTAENPSGKIRSQ------DVH 117
Query: 441 PRMLSPRNQLIRVILYNRTRLDCPFFGSPIPT--------LRWFKNGQGSNLDGGNYHVY 492
+ + +RV R + F IP+ + W K+ S + G + +
Sbjct: 118 IKAVLREPYTVRVEDQKTMRGNVAVFKCIIPSSVEAYITVVSWEKDTV-SLVSGSRFLIT 176
Query: 493 ENGSLEIKMIRKEDQGIYT--CVATNILG---KAENQVRLEVKDPTR----IYRMPEDQV 543
G+L IK ++ ED G+Y C+ + + N RL V DP I + +
Sbjct: 177 STGALYIKDVQNED-GLYNYRCITRHRYTGETRQSNSARLFVSDPANSAPSILDGFDHRK 235
Query: 544 ARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTC 603
A G V+L C+ P + WLKD+ PL + R +K L I + D GSY C
Sbjct: 236 AMAGQRVELPCKALGHP--EPDYRWLKDNMPLELSGRFQKTVTGLLIENIRPSDSGSYVC 293
Query: 604 VAS 606
S
Sbjct: 294 EVS 296
Score = 58.2 bits (139), Expect = 5e-08
Identities = 58/215 (26%), Positives = 82/215 (38%), Gaps = 26/215 (12%)
Query: 530 KDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDE--PLYI---GNRMKKE 584
K P RI + L C+ DPS V W+KD P + G R
Sbjct: 1283 KAPARILTFSGTVTTPWMKDIVLPCKAVGDPSP--AVKWMKDSNGTPSLVTIDGRRSIFS 1340
Query: 585 DDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRD 644
+ S I V D G Y+C+A+ D L V PD+PR
Sbjct: 1341 NGSFIIRTVKAEDSGYYSCIANNNWGSDEIILNLQVQVP---------------PDQPR- 1384
Query: 645 LELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLS 704
L ++ S+ L+W+PGD S I Y++Q+ ED + W P + + L
Sbjct: 1385 LTVSKTTSSSITLSWLPGDNGGSSIRGYILQYSEDNSEQ--WGSFPISPSERSYRLENLK 1442
Query: 705 PYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPE 739
Y+F + A N VG S E +T G P+
Sbjct: 1443 CGTWYKFTLTAQNGVGPGRISEIIEA-KTLGKEPQ 1476
Score = 55.1 bits (131), Expect = 4e-07
Identities = 35/116 (30%), Positives = 53/116 (45%), Gaps = 21/116 (18%)
Query: 461 LDCPFFGSPIPTLRWFKNGQGS----NLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATN 516
L C G P P ++W K+ G+ +DG ++ NGS I+ ++ ED G Y+C+A N
Sbjct: 1305 LPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRR-SIFSNGSFIIRTVKAEDSGYYSCIANN 1363
Query: 517 ILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDD 572
G E + L+V ++P DQ V S +T+SWL D
Sbjct: 1364 NWGSDEIILNLQV-------QVPPDQP---------RLTVSKTTSSSITLSWLPGD 1403
Score = 49.3 bits (116), Expect = 2e-05
Identities = 29/86 (33%), Positives = 44/86 (51%), Gaps = 7/86 (8%)
Query: 274 DLLLECIASGVPTPDIAWYKKGGDLPS----DKAKFENFNKALRITNVSEEDSGEYFCLA 329
D++L C A G P+P + W K PS D + N + I V EDSG Y C+A
Sbjct: 1302 DIVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIA 1361
Query: 330 SNKMGSIRHTISVRVKAAPYWLDEPK 355
+N GS ++++V+ P D+P+
Sbjct: 1362 NNNWGSDEIILNLQVQVPP---DQPR 1384
Score = 35.4 bits (80), Expect = 0.33
Identities = 25/103 (24%), Positives = 39/103 (37%), Gaps = 8/103 (7%)
Query: 943 PSAPRRFRVRQPNLETINLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQTK 1002
P P ++ TI L W N + GY ++ + + Q ++ SP
Sbjct: 885 PPDPPEIEIKDVKARTITLRWTMGFDGNSPITGYDIECKNKSDSWDSAQRTKDVSPQLNS 944
Query: 1003 FTVQRTDPVSRYRFTLSARTQVGSGEAVTEESPAPPNEATPTA 1045
T+ P S Y + A+ ++G E P NE T TA
Sbjct: 945 ATIIDIHPSSTYSIRMYAKNRIGKSE--------PSNELTITA 979
Score = 35.4 bits (80), Expect = 0.33
Identities = 23/86 (26%), Positives = 40/86 (46%), Gaps = 3/86 (3%)
Query: 942 VPSAPRRFRVRQPNLETINLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQT 1001
VP R V + +I L W ++ + GY L+Y N + G + SP++
Sbjct: 1378 VPPDQPRLTVSKTTSSSITLSWLPGDNGGSSIRGYILQYSEDNSEQWGSFPI---SPSER 1434
Query: 1002 KFTVQRTDPVSRYRFTLSARTQVGSG 1027
+ ++ + Y+FTL+A+ VG G
Sbjct: 1435 SYRLENLKCGTWYKFTLTAQNGVGPG 1460
Score = 34.3 bits (77), Expect = 0.73
Identities = 23/81 (28%), Positives = 33/81 (40%), Gaps = 4/81 (4%)
Query: 367 LVCRANGNPKPTVQWM--VNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNE 424
L C+A G+P P V+WM NG P + + I R + Y C +N
Sbjct: 1305 LPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIANNN 1364
Query: 425 HG--YLLANAFVSVLDVPPRM 443
G ++ N V V PR+
Sbjct: 1365 WGSDEIILNLQVQVPPDQPRL 1385
Score = 32.3 bits (72), Expect = 2.8
Identities = 29/110 (26%), Positives = 48/110 (43%), Gaps = 16/110 (14%)
Query: 31 LTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFN--IAKDPRVSMRR 88
LT T+T KD I++ C+A G+P+P+ W ++S + D R S+
Sbjct: 1289 LTFSGTVTTPWMKD--------IVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFS 1340
Query: 89 RSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPK 138
++ ++ E G Y C A N +G+ + LQV P P+
Sbjct: 1341 NGSFIIRTVKA-----EDSGYYSCIANNNWGSD-EIILNLQVQVPPDQPR 1384
>gi|110431348 deleted in colorectal carcinoma [Homo sapiens]
Length = 1447
Score = 202 bits (513), Expect = 2e-51
Identities = 217/813 (26%), Positives = 328/813 (40%), Gaps = 74/813 (9%)
Query: 265 SSQMVLRGMDLLLECIAS---GVPTPDIAWYKKGGDLP--SDKAKFENFNKALRITNV-- 317
S + +RG ++LL+C A GVP I W K G L D+ K + N +L I N+
Sbjct: 47 SDAVTMRGGNVLLDCSAESDRGVPV--IKWKKDGIHLALGMDERKQQLSNGSLLIQNILH 104
Query: 318 ---SEEDSGEYFCLAS-NKMGSI-RHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRAN 372
+ D G Y C AS GSI T V V +L + +++ G+ L C
Sbjct: 105 SRHHKPDEGLYQCEASLGDSGSIISRTAKVAVAGPLRFLSQTESVTAFMGDTVLLKCEVI 164
Query: 373 GNPKPTVQWMVNGEPLQSAPPNPNREV--AGDTIIFRDTQISSRAVYQCNTSNEHGYLLA 430
G P PT+ W N + L P + V +G I R Q +Y+C+ N
Sbjct: 165 GEPMPTIHWQKNQQDLTPIPGDSRVVVLPSGALQISR-LQPGDIGIYRCSARNPASSRTG 223
Query: 431 N-AFVSVLDVPP--RMLS--PRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLD 485
N A V +L P R L R + I L+C G P P+ W + + L
Sbjct: 224 NEAEVRILSDPGLHRQLYFLQRPSNVVAIEGKDAVLECCVSGYPPPSFTWLRGEEVIQLR 283
Query: 486 GGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVAR 545
Y + +L I + +D G+YTCV T L V P P + A
Sbjct: 284 SKKYSLLGGSNLLISNVTDDDSGMYTCVVTYKNENISASAELTVLVPPWFLNHPSNLYAY 343
Query: 546 RGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDS-LTIFGVAERDQGSYTCV 604
++ EC V P TV+W+K+ + + + + S L I GV + D+G Y CV
Sbjct: 344 ESMDIEFECTVSGKP--VPTVNWMKNGDVVIPSDYFQIVGGSNLRILGVVKSDEGFYQCV 401
Query: 605 ASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERSVRLTWIPGDA 664
A E A L ++ A P++ + P PRD+ ++ R VRL+W P
Sbjct: 402 AENEAGNAQTSAQL-IVPKPAIPSSSVL------PSAPRDVVPVLVSSRFVRLSWRPPAE 454
Query: 665 NNSPITDYVVQF--EEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSS 722
I + V F E D + + ++ PGS+ V L P Y FRV+A NE G
Sbjct: 455 AKGNIQTFTVFFSREGDNRERAL---NTTQPGSLQLTVGNLKPEAMYTFRVVAYNEWG-- 509
Query: 723 HPSLPSERYRTSGAPPESNPGDV---KGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWR 779
P S+ + + P PG V + T ++ ITW P A GP Y +
Sbjct: 510 -PGESSQPIKVATQPELQVPGPVENLQAVSTSPTSILITWEP--PAYANGPVQGYRLFCT 566
Query: 780 RRETREAWNNVTVWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDYPRAA 839
T + N+ V G Y + + Y +R A N +G G + + + D P A
Sbjct: 567 EVSTGKE-QNIEVDGLSYKLEGLKKFTEYSLRFLAYNRYGPGVSTDDITVVTLSDVPSAP 625
Query: 840 PTEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQASFPG 899
P V + V+NS +I + W S T G + Y+ +++ +++ + +
Sbjct: 626 PQNVSLEVVNSRSIKVSWLPPPSGTQNGFITGYK---------IRHRKTTRRGEMETLEP 676
Query: 900 DRLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSETKEFTTPEG------VPSAPRRFRVRQ 953
+ L + + L S Y ++ + G GP S TPE VP P VR
Sbjct: 677 NNLWYLFTGLEKGSQYSFQVSAMTVNGTGPPSNWYTAETPENDLDESQVPDQPSSLHVR- 735
Query: 954 PNLETINLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVE--NFSPNQTKFTVQRTDPV 1011
P I + W P +PN ++ GY + Y VG E Q ++++R +
Sbjct: 736 PQTNCIIMSWTPPLNPNIVVRGYIIGY------GVGSPYAETVRVDSKQRYYSIERLESS 789
Query: 1012 SRYRFTLSARTQVGSG----EAVTEESPAPPNE 1040
S Y +L A G G E+ T S P +
Sbjct: 790 SHYVISLKAFNNAGEGVPLYESATTRSITDPTD 822
Score = 154 bits (390), Expect = 4e-37
Identities = 234/1050 (22%), Positives = 399/1050 (38%), Gaps = 148/1050 (14%)
Query: 52 NILIECEAKGNPA-PSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEY 110
N+L++C A+ + P W ++ + D R L+ + + EG Y
Sbjct: 56 NVLLDCSAESDRGVPVIKWKKDGIHLALGMDERKQQLSNGSLLIQNILHSRHHKPDEGLY 115
Query: 111 QCFAR-NKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFW 169
QC A G+ +S ++ V+ PL + V G + L+C G P P I W
Sbjct: 116 QCEASLGDSGSIISRTAKVAVA-GPLRFLSQTESVTAFMGDTVLLKCEVI-GEPMPTIHW 173
Query: 170 MSSSME--PITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKV 227
+ + PI D RV +G L S + D+ Y C+AR NP
Sbjct: 174 QKNQQDLTPIPGDSRVVVLPSGALQISRLQPGDIGI-YRCSAR----------NP----- 217
Query: 228 LTNHPYNDSSLRNHPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTP 287
++ N++ +R + S G+ + P S+ + + G D +LEC SG P P
Sbjct: 218 ASSRTGNEAEVR----ILSDPGLHRQLYFLQRP----SNVVAIEGKDAVLECCVSGYPPP 269
Query: 288 DIAWYKKGGDLPSDKAKFENFNKA-LRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKA 346
W + + K+ + L I+NV+++DSG Y C+ + K +I + + V
Sbjct: 270 SFTWLRGEEVIQLRSKKYSLLGGSNLLISNVTDDDSGMYTCVVTYKNENISASAELTVLV 329
Query: 347 APYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIF 406
P++L+ P NL D C +G P PTV WM NG+ + P + + V G +
Sbjct: 330 PPWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNGDVV--IPSDYFQIVGGSNLRI 387
Query: 407 RDTQISSRAVYQCNTSNEHGYLLANAFV----------SVLDVPPRMLSPRNQLIRVILY 456
S YQC NE G +A + SVL PR + P R +
Sbjct: 388 LGVVKSDEGFYQCVAENEAGNAQTSAQLIVPKPAIPSSSVLPSAPRDVVPVLVSSRFVRL 447
Query: 457 NRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYT--CVA 514
+ R G+ I T F + +G N + + + GSL++ + + + +YT VA
Sbjct: 448 S-WRPPAEAKGN-IQTFTVFFSREGDNRERA-LNTTQPGSLQLTVGNLKPEAMYTFRVVA 504
Query: 515 TNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEP 574
N G E+ P ++ PE QV G L+ V P+ + ++W + P
Sbjct: 505 YNEWGPGES------SQPIKVATQPELQVP--GPVENLQA-VSTSPT-SILITW---EPP 551
Query: 575 LY----------------IGNRMKKEDDSLT--IFGVAERDQGSYTCVASTELDQDLAKA 616
Y G E D L+ + G+ + + S +A ++
Sbjct: 552 AYANGPVQGYRLFCTEVSTGKEQNIEVDGLSYKLEGLKKFTEYSLRFLAYNRYGPGVSTD 611
Query: 617 YLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERSVRLTWI--PGDANNSPITDYVV 674
+TV+ P+ P+++ L + RS++++W+ P N IT Y +
Sbjct: 612 DITVVTLSDVPS-----------APPQNVSLEVVNSRSIKVSWLPPPSGTQNGFITGYKI 660
Query: 675 QFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPS------LPS 728
+ + + + + P ++ L Y F+V A+ G+ PS P
Sbjct: 661 RHRKTTRRGEM---ETLEPNNLWYLFTGLEKGSQYSFQVSAMTVNGTGPPSNWYTAETPE 717
Query: 729 ERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNL---RYIVKWRRRETRE 785
S P + + V+ + N + ++WTP PN+ YI+ +
Sbjct: 718 NDLDESQVPDQPSSLHVR---PQTNCIIMSWTP-----PLNPNIVVRGYIIGYGVGSPYA 769
Query: 786 AWNNVTVWGSRYVVGQTPVYVPYEIRVQAENDFGKG------------PEPESVIGYSG- 832
V Y + + Y I ++A N+ G+G +P + Y
Sbjct: 770 ETVRVDSKQRYYSIERLESSSHYVISLKAFNNAGEGVPLYESATTRSITDPTDPVDYYPL 829
Query: 833 -EDYPRAA---------PTEVKVRVMNSTAISLQW--NRVYSDTVQGQLREYRAYYWRES 880
+D+P + P V+ + A+ + W N V + ++R Y WR S
Sbjct: 830 LDDFPTSVPDLSTPMLPPVGVQAVALTHDAVRVSWADNSVPKNQKTSEVRLY-TVRWRTS 888
Query: 881 SLLKNLWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSETKEFTTPE 940
+ S+ S+ L+ P + Y+ ++V R S T TT E
Sbjct: 889 FSASAKYKSEDTTSLSYTATGLK-------PNTMYEFSVMVTKNRRSSTWSMTAHATTYE 941
Query: 941 GVP-SAPRRFRV--RQPNLETINLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVENFS 997
P SAP+ V R+ + + W P NG + Y L Y + I+E S
Sbjct: 942 AAPTSAPKDLTVITREGKPRAVIVSWQPPLEANGKITAYILFYTLDKNIPIDDWIMETIS 1001
Query: 998 PNQTKFTVQRTDPVSRYRFTLSARTQVGSG 1027
++ + + + Y F + AR G G
Sbjct: 1002 GDRLTHQIMDLNLDTMYYFRIQARNSKGVG 1031
Score = 77.4 bits (189), Expect = 7e-14
Identities = 80/292 (27%), Positives = 112/292 (38%), Gaps = 45/292 (15%)
Query: 51 DNILIECEAKGNPAPSFHWTRNSRFFN-IAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGE 109
D +L++CE G P P+ HW +N + I D RV + SG L I G G
Sbjct: 155 DTVLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRVVV-LPSGALQISRLQPGD----IGI 209
Query: 110 YQCFARNKFGTALSNRIRLQVSKSP-----LWPKENLDPVVVQEGAPLTLQCNPPPGLPS 164
Y+C ARN + N +++ P L+ + VV EG L+C G P
Sbjct: 210 YRCSARNPASSRTGNEAEVRILSDPGLHRQLYFLQRPSNVVAIEGKDAVLEC-CVSGYPP 268
Query: 165 PVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFT 224
P W+ + K+ S +L SNV D Y+C + I T
Sbjct: 269 PSFTWLRGEEVIQLRSKKYSLLGGSNLLISNV-TDDDSGMYTCVVTYK-NENISASAELT 326
Query: 225 LKVLTNHPYNDSSLRNHPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGV 284
+ V P+ NHP S+ MD+ EC SG
Sbjct: 327 VLV---PPW----FLNHP----------------------SNLYAYESMDIEFECTVSGK 357
Query: 285 PTPDIAWYKKGG-DLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGS 335
P P + W K G +PSD + LRI V + D G Y C+A N+ G+
Sbjct: 358 PVPTVNWMKNGDVVIPSDYFQIVG-GSNLRILGVVKSDEGFYQCVAENEAGN 408
Score = 33.9 bits (76), Expect = 0.95
Identities = 25/81 (30%), Positives = 37/81 (45%), Gaps = 9/81 (11%)
Query: 534 RIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKE---DDSLTI 590
R P D V RG V L+C + D + + + W KD L +G +K+ + SL I
Sbjct: 41 RFLSEPSDAVTMRGGNVLLDCSAESDRGVPV-IKWKKDGIHLALGMDERKQQLSNGSLLI 99
Query: 591 FGVA-----ERDQGSYTCVAS 606
+ + D+G Y C AS
Sbjct: 100 QNILHSRHHKPDEGLYQCEAS 120
Score = 33.5 bits (75), Expect = 1.2
Identities = 45/198 (22%), Positives = 80/198 (40%), Gaps = 17/198 (8%)
Query: 642 PRDLELTDLAERSVRLTW----IPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVN 697
P ++ L +VR++W +P + S + Y V++ + S+ S++
Sbjct: 847 PVGVQAVALTHDAVRVSWADNSVPKNQKTSEVRLYTVRWRTSFSASAKYK--SEDTTSLS 904
Query: 698 SAVLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGD---VKGEGTRKNN 754
L P Y+F V+ SS S+ + T A P S P D + EG +
Sbjct: 905 YTATGLKPNTMYEFSVMVTKNRRSSTWSMTAHA-TTYEAAPTSAPKDLTVITREG-KPRA 962
Query: 755 MEITWTPMNATSAFGPNLRYIVKWR--RRETREAWNNVTVWGSR--YVVGQTPVYVPYEI 810
+ ++W P A G YI+ + + + W T+ G R + + + Y
Sbjct: 963 VIVSWQP--PLEANGKITAYILFYTLDKNIPIDDWIMETISGDRLTHQIMDLNLDTMYYF 1020
Query: 811 RVQAENDFGKGPEPESVI 828
R+QA N G GP + ++
Sbjct: 1021 RIQARNSKGVGPLSDPIL 1038
>gi|21359935 Down syndrome cell adhesion molecule like 1 [Homo
sapiens]
Length = 2113
Score = 202 bits (513), Expect = 2e-51
Identities = 249/1055 (23%), Positives = 411/1055 (38%), Gaps = 133/1055 (12%)
Query: 36 TITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSG-TLV 94
T+T + K I +++ C G+P + W RN+ + D +S+R S TL+
Sbjct: 378 TLTPKKLKTGI---GSTVILSCALTGSPEFTIRWYRNTEL--VLPDEAISIRGLSNETLL 432
Query: 95 IDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTL 154
I + + G YQCFA K TA I +P + VV G +L
Sbjct: 433 IT----SAQKSHSGAYQCFATRKAQTAQDFAIIALEDGTPRIVS-SFSEKVVNPGEQFSL 487
Query: 155 QCNPPPGLPSPVIFWMSSSMEPITQD--KRVSQGHNGD---LYFSNVMLQDMQTD--YSC 207
C G P P + W EPI +D R +Q D + NV ++ Y C
Sbjct: 488 MC-AAKGAPPPTVTWALDD-EPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRC 545
Query: 208 NARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRNHPDMYSARGVAERTPSFMYPQGTASSQ 267
AR + + ++ ++R P + + R +
Sbjct: 546 TAR-----NLVGSAEYQARI---------NVRGPPSIRAMRNIT---------------- 575
Query: 268 MVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEE-DSGEYF 326
+ G D L+ C G P I WYK LP + + N L++T+V + D GEY
Sbjct: 576 -AVAGRDTLINCRVIGYPYYSIKWYKDALLLPDNHRQVVFENGTLKLTDVQKGMDEGEYL 634
Query: 327 C-LASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLV---CRANGNPKPT-VQW 381
C + SI ++ V VK P L +P P G+L+ C + P + W
Sbjct: 635 CSVLIQPQLSISQSVHVAVKVPP--LIQPFEF--PPASIGQLLYIPCVVSSGDMPIRITW 690
Query: 382 MVNGEPLQSAPPNPNREVAGDTIIFRD----TQISSRAV-----YQCNTSNEHGYLLANA 432
+G+ + S +G TI ++ QISS ++ Y C SN A A
Sbjct: 691 RKDGQVIISG--------SGVTIESKEFMSSLQISSVSLKHNGNYTCIASN------AAA 736
Query: 433 FVS-----VLDVPPR-MLSPRNQLIRVILYNRTR-LDCPFFGSPIPTLRWFKNGQGSNLD 485
VS ++ VPPR ++ P NQ +Y + L+C G P P + W K+ +GS
Sbjct: 737 TVSRERQLIVRVPPRFVVQPNNQ---DGIYGKAGVLNCSVDGYPPPKVMW-KHAKGSGNP 792
Query: 486 G--------GNYHVYENGSLEIKMIRKEDQGIYTCVATNILGK-AENQVRLEVKDPTRIY 536
G + N SL I+ + +ED G Y C A+N +G + L VK P I
Sbjct: 793 QQYHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIPAMIT 852
Query: 537 RMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAER 596
P +A +G +L C + + + + W K D + + D + + +A +
Sbjct: 853 SHPNTTIAIKGHAKELNCTARGERPI--IIRWEKGDTVI--------DPDRVMRYAIATK 902
Query: 597 DQGSYTCVASTEL---DQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAER 653
D G V++ +L D+ + + + L L P P +LE+ ++ R
Sbjct: 903 DNGDEV-VSTLKLKPADRGDSVFFSCHAINSYGEDRGLIQLTVQEPPDPPELEIREVKAR 961
Query: 654 SVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSA-VLRLSPYVNYQFR 712
S+ L W NS IT + ++++ ++N A ++ L P Y R
Sbjct: 962 SMNLRWTQRFDGNSIITGFDIEYKNKSDSWDFKQSTRNISPTINQANIVDLHPASVYSIR 1021
Query: 713 VIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNL 772
+ + N++G S PS T A P+ P DV + ++++TW G
Sbjct: 1022 MYSFNKIGRSEPS-KELTISTEEAAPDGPPMDVTLQPVTSQSIQVTWKAPKKELQNGVIR 1080
Query: 773 RYIVKWRRRETREAWN------NVTVWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPES 826
Y + +R T Y + + Y + VQA N G GP
Sbjct: 1081 GYQIGYRENSPGSNGQYSIVEMKATGDSEVYTLDNLKKFAQYGVVVQAFNRAGTGPSSSE 1140
Query: 827 VIGYSGEDYPRAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNL 886
+ + ED P P V+ + S + W+ T+ G L+ YR +W S +
Sbjct: 1141 INATTLEDVPSQPPENVRALSITSDVAVISWSEPPRSTLNGVLKGYRVIFW--SLYVDGE 1198
Query: 887 WVSQKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSETKEFTTPEGVPSAP 946
W + + LRG+ ++NY ++++ GDG RS T E VP P
Sbjct: 1199 WGEMQNITTTRERVELRGMEK----FTNYSVQVLAYTQAGDGVRSSVLYIQTKEDVPGPP 1254
Query: 947 RRFRVRQPNLETINLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQ 1006
+ + ++ + W P PNG++ YT+ + + G+ SP Q + +
Sbjct: 1255 AGIKAVPSSASSVVVSWLPPTKPNGVIRKYTI-FCSSPGSGQPAPSEYETSPEQLFYRIA 1313
Query: 1007 RTDPVSRYRFTLSARTQVGSGEAVTEESPAPPNEA 1041
+ +Y ++A T G G + + + P +A
Sbjct: 1314 HLNRGQQYLLWVAAVTSAGRGNSSEKVTIEPAGKA 1348
Score = 145 bits (365), Expect = 3e-34
Identities = 157/621 (25%), Positives = 257/621 (41%), Gaps = 58/621 (9%)
Query: 6 PPP---------WVHAAFLLCLLSLGGAIEIPMDLTQPPTITKQSAKDHIVDPRDNILIE 56
PPP W+ FLL L SL A P D+ S + +++
Sbjct: 50 PPPRRIGPLYGMWL-VTFLLLLDSLHKAR--PEDVGTSLYFVNDSLQQVTFSSSVGVVVP 106
Query: 57 CEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEY--EGEYQCFA 114
C A G+P+ + W + +I P + +GTL + S + + +Y C A
Sbjct: 107 CPAAGSPSAALRWYLATGD-DIYDVPHIRHVHANGTLQLYPFSPSAFNSFIHDNDYFCTA 165
Query: 115 RNKFGTALSNRIRLQ-VSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPS--PVIFWMS 171
N G S IR++ V + P + ++ G +C P + V+ W
Sbjct: 166 ENAAGKIRSPNIRVKAVFREPYTVR--VEDQRSMRGNVAVFKCLIPSSVQEYVSVVSWEK 223
Query: 172 SSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNH 231
++ I + R ++G LY S+V +D + Y C +T H
Sbjct: 224 DTVS-IIPEHRFFITYHGGLYISDVQKEDALSTYRC--------------------ITKH 262
Query: 232 PYNDSSLRNHPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAW 291
Y+ + +++ S AE P+ + SQ V G + L C ASG P P I W
Sbjct: 263 KYSGETRQSNGARLSVTDPAESIPTIL---DGFHSQEVWAGHTVELPCTASGYPIPAIRW 319
Query: 292 YKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWL 351
K G LP+D +++ L I+++ EDSG Y C +N GS T + V +
Sbjct: 320 LKDGRPLPAD-SRWTKRITGLTISDLRTEDSGTYICEVTNTFGSAEATGILMVIDPLHVT 378
Query: 352 DEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQI 411
PK L G L C G+P+ T++W N E + R ++ +T++ Q
Sbjct: 379 LTPKKLKTGIGSTVILSCALTGSPEFTIRWYRNTELVLPDEAISIRGLSNETLLITSAQK 438
Query: 412 SSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIP 471
S YQC + + A +++ D PR++S ++ + V + L C G+P P
Sbjct: 439 SHSGAYQCFATRKAQTAQDFAIIALEDGTPRIVSSFSEKV-VNPGEQFSLMCAAKGAPPP 497
Query: 472 TLRWFKNGQGSNLDGG---NYHVYENGS----LEIKMIRKEDQGIYTCVATNILGKAENQ 524
T+ W + + DG N + +G+ + + + D G+Y C A N++G AE Q
Sbjct: 498 TVTWALDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQ 557
Query: 525 VRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNR-MKK 583
R+ V+ P I R + A G + CRV P ++ W KD L +R +
Sbjct: 558 ARINVRGPPSI-RAMRNITAVAGRDTLINCRVIGYP--YYSIKWYKDALLLPDNHRQVVF 614
Query: 584 EDDSLTIFGVAE-RDQGSYTC 603
E+ +L + V + D+G Y C
Sbjct: 615 ENGTLKLTDVQKGMDEGEYLC 635
Score = 72.8 bits (177), Expect = 2e-12
Identities = 90/376 (23%), Positives = 147/376 (39%), Gaps = 33/376 (8%)
Query: 275 LLLECIASGVPTPDIAWYKKGGDLPSDKAKFENF--NKALRITNVSEE------DSGEYF 326
+++ C A+G P+ + WY GD D + N L++ S +YF
Sbjct: 103 VVVPCPAAGSPSAALRWYLATGDDIYDVPHIRHVHANGTLQLYPFSPSAFNSFIHDNDYF 162
Query: 327 CLASNKMGSIRHTISVRVKAA---PYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMV 383
C A N G IR ++RVKA PY + + G C + + V +
Sbjct: 163 CTAENAAGKIRSP-NIRVKAVFREPYTVRVEDQRSMR-GNVAVFKCLIPSSVQEYVSVVS 220
Query: 384 NGEPLQSAPPNPNREVA--GDTIIFRDTQISSRAVYQCNTSNEHGYLLAN---AFVSVLD 438
+ S P + G I + + + Y+C T +++ A +SV D
Sbjct: 221 WEKDTVSIIPEHRFFITYHGGLYISDVQKEDALSTYRCITKHKYSGETRQSNGARLSVTD 280
Query: 439 ----VPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYEN 494
+P + +Q V + L C G PIP +RW K+G+ L +
Sbjct: 281 PAESIPTILDGFHSQ--EVWAGHTVELPCTASGYPIPAIRWLKDGRP--LPADSRWTKRI 336
Query: 495 GSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLEC 554
L I +R ED G Y C TN G AE L V DP + P+ G+TV L C
Sbjct: 337 TGLTISDLRTEDSGTYICEVTNTFGSAEATGILMVIDPLHVTLTPKKLKTGIGSTVILSC 396
Query: 555 RVKHDPSLKLTVSWLKDDEPLYIGNRMK---KEDDSLTIFGVAERDQGSYTCVASTELDQ 611
+ P + T+ W ++ E + + +++L I + G+Y C A+ +
Sbjct: 397 ALTGSP--EFTIRWYRNTELVLPDEAISIRGLSNETLLITSAQKSHSGAYQCFATRK--A 452
Query: 612 DLAKAYLTVLADQATP 627
A+ + + + TP
Sbjct: 453 QTAQDFAIIALEDGTP 468
Score = 61.6 bits (148), Expect = 4e-09
Identities = 78/295 (26%), Positives = 121/295 (41%), Gaps = 32/295 (10%)
Query: 550 VQLECRVKHDPSLKLTVSWLKDDEPLYI-----GNRMKKEDDSLTIFGVAERDQGSYTCV 604
V+L C DP+ V W KD E I G+R+ + +L + V D G YTC
Sbjct: 1367 VRLPCNSVGDPAP--AVKWTKDSEDSAIPVSMDGHRLIHTNGTLLLRAVKAEDSGYYTCT 1424
Query: 605 ASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERSVRLTWIPGDA 664
A+ D T++ N L +P PD+PR L ++ + S+ LTWIPGD
Sbjct: 1425 ATNTGGFD------TIIV------NLLVQVP---PDQPR-LTVSKTSASSITLTWIPGDN 1468
Query: 665 NNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHP 724
S I +V+Q+ D + W D + + L Y+ ++ A N VGS
Sbjct: 1469 GGSSIRGFVLQYSVDNSEE--WKDVFISSSERSFKLDSLKCGTWYKVKLAAKNSVGSGRI 1526
Query: 725 SLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETR 784
S E +T G P + + T N+ + P ++++R + T
Sbjct: 1527 SEIIEA-KTHGREPSFSKD--QHLFTHINSTHARLNLQGWNNGGCPITAIVLEYRPKGT- 1582
Query: 785 EAWNNVTVWGSRYV-VGQTPVYVPYEIRVQAENDFGKGPEPE--SVIGYSGEDYP 836
AW + S V + + YE+R++A N G G E + + Y G P
Sbjct: 1583 WAWQGLRANSSGEVFLTELREATWYELRMRACNSAGCGNETAQFATLDYDGSTIP 1637
Score = 53.1 bits (126), Expect = 2e-06
Identities = 76/343 (22%), Positives = 132/343 (38%), Gaps = 48/343 (13%)
Query: 460 RLDCPFFGSPIPTLRWFKNGQGSNLD---GGNYHVYENGSLEIKMIRKEDQGIYTCVATN 516
RL C G P P ++W K+ + S + G+ ++ NG+L ++ ++ ED G YTC ATN
Sbjct: 1368 RLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNGTLLLRAVKAEDSGYYTCTATN 1427
Query: 517 ILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLY 576
G V L + ++P DQ V + +T++W+ D
Sbjct: 1428 TGGFDTIIVNL-------LVQVPPDQP---------RLTVSKTSASSITLTWIPGD---- 1467
Query: 577 IGNRMKKEDDSLTIFGVAERDQGSYTCVASTE----LDQDLAKAYLTV--LADQATPTNR 630
N + + V ++ ++S+E LD + V A + + R
Sbjct: 1468 --NGGSSIRGFVLQYSVDNSEEWKDVFISSSERSFKLDSLKCGTWYKVKLAAKNSVGSGR 1525
Query: 631 LAALPKGR-----PDRPRDLEL-TDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPG 684
++ + + + P +D L T + RL + PIT V+++ G
Sbjct: 1526 ISEIIEAKTHGREPSFSKDQHLFTHINSTHARLNLQGWNNGGCPITAIVLEYR----PKG 1581
Query: 685 VWHDHSKYPGSVNSAVL-RLSPYVNYQFRVIAINEVGSSHPS--LPSERYRTSGAPPESN 741
W S L L Y+ R+ A N G + + + Y S PP +
Sbjct: 1582 TWAWQGLRANSSGEVFLTELREATWYELRMRACNSAGCGNETAQFATLDYDGSTIPPIKS 1641
Query: 742 PGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETR 784
+GEG + P+ + G L +IV+ +R+E R
Sbjct: 1642 ---AQGEGDDVKKLFTIGCPV-ILATLGVALLFIVRKKRKEKR 1680
Score = 40.0 bits (92), Expect = 0.013
Identities = 30/108 (27%), Positives = 48/108 (44%), Gaps = 15/108 (13%)
Query: 260 PQGTASSQMVLRG--------MDLLLECIASGVPTPDIAWYKKGGD----LPSDKAKFEN 307
P G A ++++ G D+ L C + G P P + W K D + D + +
Sbjct: 1344 PAGKAPAKIISFGGTVTTPWMKDVRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIH 1403
Query: 308 FNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPK 355
N L + V EDSG Y C A+N G +++ V+ P D+P+
Sbjct: 1404 TNGTLLLRAVKAEDSGYYTCTATNTGGFDTIIVNLLVQVPP---DQPR 1448
Score = 36.2 bits (82), Expect = 0.19
Identities = 25/87 (28%), Positives = 41/87 (47%), Gaps = 8/87 (9%)
Query: 363 EDGRLVCRANGNPKPTVQWMVNGEPLQSAPP---NPNREV-AGDTIIFRDTQISSRAVYQ 418
+D RL C + G+P P V+W + E SA P + +R + T++ R + Y
Sbjct: 1365 KDVRLPCNSVGDPAPAVKWTKDSE--DSAIPVSMDGHRLIHTNGTLLLRAVKAEDSGYYT 1422
Query: 419 CNTSNEHGY--LLANAFVSVLDVPPRM 443
C +N G+ ++ N V V PR+
Sbjct: 1423 CTATNTGGFDTIIVNLLVQVPPDQPRL 1449
Score = 31.2 bits (69), Expect = 6.1
Identities = 33/138 (23%), Positives = 55/138 (39%), Gaps = 11/138 (7%)
Query: 942 VPSAPRRFRVRQPNLETINLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQT 1001
VP R V + + +I L W ++ + G+ L+Y N + + S ++
Sbjct: 1442 VPPDQPRLTVSKTSASSITLTWIPGDNGGSSIRGFVLQYSVDNSEEWKDVFI---SSSER 1498
Query: 1002 KFTVQRTDPVSRYRFTLSARTQVGSG------EAVTE-ESPAPPNEATPTAAYTNNQADI 1054
F + + Y+ L+A+ VGSG EA T P+ + + A +
Sbjct: 1499 SFKLDSLKCGTWYKVKLAAKNSVGSGRISEIIEAKTHGREPSFSKDQHLFTHINSTHARL 1558
Query: 1055 ATQGWFIGLMCAIALLVL 1072
QGW G C I +VL
Sbjct: 1559 NLQGWNNG-GCPITAIVL 1575
>gi|193083163 roundabout, axon guidance receptor, homolog 2 isoform
ROBO2a [Homo sapiens]
Length = 1394
Score = 193 bits (490), Expect = 9e-49
Identities = 218/862 (25%), Positives = 345/862 (40%), Gaps = 113/862 (13%)
Query: 127 RLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQG 186
RL+ P E+ V+V +G P TL C G P+P I W E + DK +
Sbjct: 39 RLRQEDFPPRIVEHPSDVIVSKGEPTTLNCKAE-GRPTPTIEWYKDG-ERVETDKDDPRS 96
Query: 187 H-----NGDLYFSNVM----LQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSS 237
H +G L+F ++ + + Y C AR + + + + +L D
Sbjct: 97 HRMLLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALL-----RDDF 151
Query: 238 LRNHPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIAS-GVPTPDIAWYKKGG 296
+N D+ +V G +LEC G P P I W K
Sbjct: 152 RQNPTDV-----------------------VVAAGEPAILECQPPRGHPEPTIYWKKDKV 188
Query: 297 DLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSI-RHTISVRVKAAPYWLDEPK 355
+ + + L I+N + D+G Y C+ +N +G + V P +L P
Sbjct: 189 RIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRRPI 248
Query: 356 NLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGD-TIIFRDTQISSR 414
N ++ E C+ G+P+PTV+W + L P ++ D T+ + T +
Sbjct: 249 NQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADL----PRGRYDIKDDYTLRIKKTMSTDE 304
Query: 415 AVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRT-RLDCPFFGSPIPTL 473
Y C N G + A+A ++V P ++ PR+Q ++ RT C G+P P +
Sbjct: 305 GTYMCIAENRVGKMEASATLTVRAPPQFVVRPRDQ---IVAQGRTVTFPCETKGNPQPAV 361
Query: 474 RWFKNGQGSNL-------DGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVR 526
W K G + L V G L I I++ D G Y C A + G + +
Sbjct: 362 FWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQ 421
Query: 527 LEVKD------PTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDE--PLYIG 578
LEV D P I + P +Q T L+C+ DP +SWLK+ P
Sbjct: 422 LEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLP--VISWLKEGFTFPGRDP 479
Query: 579 NRMKKEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNR--LAALPK 636
+E +L I + D G+YTCVA++ + A L V AT + L+ LP
Sbjct: 480 RATIQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLP- 538
Query: 637 GRPDRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSV 696
G P +P ++TD+ + SV L+W PG P + Y+++ Q W + + +
Sbjct: 539 GPPSKP---QVTDVTKNSVTLSWQPGTPGTLPASAYIIE-AFSQSVSNSWQTVANHVKTT 594
Query: 697 NSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPP----------ESNPGDVK 746
V L P Y F V AIN G S PS S+ RT P + GDV
Sbjct: 595 LYTVRGLRPNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVL 654
Query: 747 GEGTRKNN--------MEITWTPMNATSAFGPNLRYIVKWRR-RETREAWNNVTV---WG 794
R +N +++TWT ++ F R + + + +W N+
Sbjct: 655 ---VRLHNPVVLTPTTVQVTWT-VDRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTE 710
Query: 795 SRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDYPRAAPTEVKVRVM---NST 851
V+ V YEI+V+ + +G + ES + E+ P A P V V + NST
Sbjct: 711 RSAVLVNLKKGVTYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNST 770
Query: 852 AISLQWNRVYSDTVQGQLREYRAY-YWRESSLLKNLWVSQKRQQASFPGDRLRGVVSRLF 910
+IS+ W+ D G ++EY+ + E+ N V + ++ LF
Sbjct: 771 SISVSWDPPPPDHQNGIIQEYKIWCLGNETRFHINKTVDAAIRSV---------IIGGLF 821
Query: 911 PYSNYKLEMVVVNGRGDGPRSE 932
P Y++E+ G G +SE
Sbjct: 822 PGIQYRVEVAASTSAGVGVKSE 843
Score = 186 bits (471), Expect = 1e-46
Identities = 152/514 (29%), Positives = 218/514 (42%), Gaps = 52/514 (10%)
Query: 34 PPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRR--SG 91
PP I + + D IV + + C+A+G P P+ W ++ KD S R SG
Sbjct: 46 PPRIVEHPS-DVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSG 104
Query: 92 TLV-IDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGA 150
+L + G R + EG Y C ARN G A+S L+V+ ++N VVV G
Sbjct: 105 SLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGE 164
Query: 151 PLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNAR 210
P L+C PP G P P I+W + +++R+S G L SN D Y+C
Sbjct: 165 PAILECQPPRGHPEPTIYWKKDKVRIDDKEERISI-RGGKLMISNTRKSDAGM-YTC--- 219
Query: 211 FHFTHTIQQKNPFTLKVLTNHPYNDSSLRNHPDMYSARGVAERTPSFMYPQGTASSQMVL 270
V TN + D A P+F+ +Q+VL
Sbjct: 220 ----------------VGTN-------MVGERDSDPAELTVFERPTFL---RRPINQVVL 253
Query: 271 RGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLAS 330
+ C G P P + W K DLP + ++ + LRI D G Y C+A
Sbjct: 254 EEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKD-DYTLRIKKTMSTDEGTYMCIAE 312
Query: 331 NKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGE---- 386
N++G + + ++ V+A P ++ P++ I+A G C GNP+P V W G
Sbjct: 313 NRVGKMEASATLTVRAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLL 372
Query: 387 -PLQSAPPNPNREVA--GDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDV---- 439
P Q PN V+ GD I + Q S Y C G +LA A + V DV
Sbjct: 373 FPNQPQQPNSRCSVSPTGDLTI-TNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDR 431
Query: 440 -PPRML-SPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSL 497
PP +L P NQ + V L C G P+P + W K G + E G+L
Sbjct: 432 PPPIILQGPANQTLAV--DGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQGTL 489
Query: 498 EIKMIRKEDQGIYTCVATNILGKAENQVRLEVKD 531
+IK +R D G YTCVAT+ G+ L+V +
Sbjct: 490 QIKNLRISDTGTYTCVATSSSGETSWSAVLDVTE 523
Score = 161 bits (407), Expect = 4e-39
Identities = 222/894 (24%), Positives = 358/894 (40%), Gaps = 115/894 (12%)
Query: 265 SSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNV------- 317
S +V +G L C A G PTP I WYK G + +DK + L ++
Sbjct: 54 SDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVH 113
Query: 318 ---SEEDSGEYFCLASNKMG-SIRHTISVRVKAA-PYWLDEPKNLILAPGEDGRLVCRA- 371
S+ D G Y C+A N +G ++ S+ V + P ++++A GE L C+
Sbjct: 114 GRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPP 173
Query: 372 NGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLAN 431
G+P+PT+ W + ++ + G ++ +T+ S +Y C +N G ++
Sbjct: 174 RGHPEPTIYW--KKDKVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSD 231
Query: 432 -AFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYH 490
A ++V + P + P NQ+ V+ C G P PT+RW K+ ++L G Y
Sbjct: 232 PAELTVFERPTFLRRPINQV--VLEEEAVEFRCQVQGDPQPTVRWKKDD--ADLPRGRYD 287
Query: 491 VYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTV 550
+ ++ +L IK D+G Y C+A N +GK E L V+ P + P DQ+ +G TV
Sbjct: 288 IKDDYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQFVVRPRDQIVAQGRTV 347
Query: 551 QLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDS---------LTIFGVAERDQGSY 601
C K +P + V W K+ + ++ +S LTI + D G Y
Sbjct: 348 TFPCETKGNP--QPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYY 405
Query: 602 TCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERSVRL---T 658
C A T LAKA L V D T DRP + L A +++ +
Sbjct: 406 ICQALTVAGSILAKAQLEV-TDVLT-------------DRPPPIILQGPANQTLAVDGTA 451
Query: 659 WIPGDANNSPITDYVVQFEEDQFQ-PGVWHDHS-KYPGSVNSAVLRLSPYVNY------- 709
+ A P+ V+ + ++ F PG + + G++ LR+S Y
Sbjct: 452 LLKCKATGDPLP--VISWLKEGFTFPGRDPRATIQEQGTLQIKNLRISDTGTYTCVATSS 509
Query: 710 --QFRVIAINEVGSSHPSLPSERYRTSGAP-PESNPGDVKGEGTRKNNMEITWTPMNATS 766
+ A+ +V S ++ S+ Y S P P S P + KN++ ++W P T
Sbjct: 510 SGETSWSAVLDVTESGATI-SKNYDLSDLPGPPSKP---QVTDVTKNSVTLSWQP--GTP 563
Query: 767 AFGPNLRYIVKWRRRETREAWNNVT--VWGSRYVVGQTPVYVPYEIRVQAENDFG-KGPE 823
P YI++ + +W V V + Y V Y V+A N G P
Sbjct: 564 GTLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLRPNTIYLFMVRAINPQGLSDPS 623
Query: 824 PESVIGYSGEDYPRAAPTE----------VKVR-----VMNSTAISLQWNRVYSDTVQGQ 868
P S + + P A + V VR V+ T + + W D
Sbjct: 624 PMSDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNPVVLTPTTVQVTWT---VDRQPQF 680
Query: 869 LREYRAYYWRESSLLKNLWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDG 928
++ YR Y + S L S + A P +R V+ L Y++++ G
Sbjct: 681 IQGYRVMYRQTSGLQATS--SWQNLDAKVPTER-SAVLVNLKKGVTYEIKVRPYFNEFQG 737
Query: 929 PRSETKEFTTPEGVPSAPRR----FRVRQPNLETINLEWD--HPEHPNGIMIGYTLKYVA 982
SE+K T E PSAP + V N +I++ WD P+H NGI+ Y + +
Sbjct: 738 MDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPDHQNGIIQEYKIWCL- 796
Query: 983 FNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESPAP----- 1037
G + I + + P +YR ++A T G G + P P
Sbjct: 797 --GNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVG---VKSEPQPIIIGR 851
Query: 1038 PNEATPTA---AYTNNQADIATQGWF---IGLMCAIALLVLILLIVCFIKRSRG 1085
NE T + T D+ Q F IG C + L+ + + K+ +G
Sbjct: 852 RNEVVITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKKRKG 905
Score = 72.8 bits (177), Expect = 2e-12
Identities = 76/322 (23%), Positives = 124/322 (38%), Gaps = 57/322 (17%)
Query: 28 PMDLT--QPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSR-----FFNIAK 80
P +LT + PT ++ +++ + + C+ +G+P P+ W ++ ++I
Sbjct: 232 PAELTVFERPTFLRRPINQVVLE-EEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKD 290
Query: 81 DPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKEN 140
D + +++ T EG Y C A N+ G + L V P +
Sbjct: 291 DYTLRIKKTMST-------------DEGTYMCIAENRVG-KMEASATLTVRAPPQFVVRP 336
Query: 141 LDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSM-------EPITQDKRVSQGHNGDLYF 193
D +V Q G +T C G P P +FW +P + R S GDL
Sbjct: 337 RDQIVAQ-GRTVTFPCE-TKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTI 394
Query: 194 SNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRNHPDMYSARGVAER 253
+N+ D Y C A + + VLT+ P
Sbjct: 395 TNIQRSDAGY-YICQALTVAGSILAKAQLEVTDVLTDRP--------------------- 432
Query: 254 TPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPS-DKAKFENFNKAL 312
P + QG A+ + + G LL+C A+G P P I+W K+G P D L
Sbjct: 433 PPIIL--QGPANQTLAVDG-TALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQGTL 489
Query: 313 RITNVSEEDSGEYFCLASNKMG 334
+I N+ D+G Y C+A++ G
Sbjct: 490 QIKNLRISDTGTYTCVATSSSG 511
Score = 37.0 bits (84), Expect = 0.11
Identities = 34/139 (24%), Positives = 61/139 (43%), Gaps = 15/139 (10%)
Query: 12 AAFLLC-LLSLGGAI------EIPMDLT-QPPTITKQSAKDHIVDPRDNILIECEAKGNP 63
A + +C L++ G+I E+ LT +PP I Q + + L++C+A G+P
Sbjct: 402 AGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDP 461
Query: 64 APSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALS 123
P W + F +DPR +++ + + + R G Y C A + G
Sbjct: 462 LPVISWLKEGFTFP-GRDPRATIQEQGTLQIKNLRISD-----TGTYTCVATSSSGETSW 515
Query: 124 NRIRLQVSKSPLWPKENLD 142
+ + L V++S +N D
Sbjct: 516 SAV-LDVTESGATISKNYD 533
>gi|61888896 roundabout, axon guidance receptor, homolog 2 isoform
ROBO2b [Homo sapiens]
Length = 1378
Score = 193 bits (490), Expect = 9e-49
Identities = 218/862 (25%), Positives = 345/862 (40%), Gaps = 113/862 (13%)
Query: 127 RLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQG 186
RL+ P E+ V+V +G P TL C G P+P I W E + DK +
Sbjct: 23 RLRQEDFPPRIVEHPSDVIVSKGEPTTLNCKAE-GRPTPTIEWYKDG-ERVETDKDDPRS 80
Query: 187 H-----NGDLYFSNVM----LQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSS 237
H +G L+F ++ + + Y C AR + + + + +L D
Sbjct: 81 HRMLLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALL-----RDDF 135
Query: 238 LRNHPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIAS-GVPTPDIAWYKKGG 296
+N D+ +V G +LEC G P P I W K
Sbjct: 136 RQNPTDV-----------------------VVAAGEPAILECQPPRGHPEPTIYWKKDKV 172
Query: 297 DLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSI-RHTISVRVKAAPYWLDEPK 355
+ + + L I+N + D+G Y C+ +N +G + V P +L P
Sbjct: 173 RIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRRPI 232
Query: 356 NLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGD-TIIFRDTQISSR 414
N ++ E C+ G+P+PTV+W + L P ++ D T+ + T +
Sbjct: 233 NQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADL----PRGRYDIKDDYTLRIKKTMSTDE 288
Query: 415 AVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRT-RLDCPFFGSPIPTL 473
Y C N G + A+A ++V P ++ PR+Q ++ RT C G+P P +
Sbjct: 289 GTYMCIAENRVGKMEASATLTVRAPPQFVVRPRDQ---IVAQGRTVTFPCETKGNPQPAV 345
Query: 474 RWFKNGQGSNL-------DGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVR 526
W K G + L V G L I I++ D G Y C A + G + +
Sbjct: 346 FWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQ 405
Query: 527 LEVKD------PTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDE--PLYIG 578
LEV D P I + P +Q T L+C+ DP +SWLK+ P
Sbjct: 406 LEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLP--VISWLKEGFTFPGRDP 463
Query: 579 NRMKKEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNR--LAALPK 636
+E +L I + D G+YTCVA++ + A L V AT + L+ LP
Sbjct: 464 RATIQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLP- 522
Query: 637 GRPDRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSV 696
G P +P ++TD+ + SV L+W PG P + Y+++ Q W + + +
Sbjct: 523 GPPSKP---QVTDVTKNSVTLSWQPGTPGTLPASAYIIE-AFSQSVSNSWQTVANHVKTT 578
Query: 697 NSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPP----------ESNPGDVK 746
V L P Y F V AIN G S PS S+ RT P + GDV
Sbjct: 579 LYTVRGLRPNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVL 638
Query: 747 GEGTRKNN--------MEITWTPMNATSAFGPNLRYIVKWRR-RETREAWNNVTV---WG 794
R +N +++TWT ++ F R + + + +W N+
Sbjct: 639 ---VRLHNPVVLTPTTVQVTWT-VDRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTE 694
Query: 795 SRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDYPRAAPTEVKVRVM---NST 851
V+ V YEI+V+ + +G + ES + E+ P A P V V + NST
Sbjct: 695 RSAVLVNLKKGVTYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNST 754
Query: 852 AISLQWNRVYSDTVQGQLREYRAY-YWRESSLLKNLWVSQKRQQASFPGDRLRGVVSRLF 910
+IS+ W+ D G ++EY+ + E+ N V + ++ LF
Sbjct: 755 SISVSWDPPPPDHQNGIIQEYKIWCLGNETRFHINKTVDAAIRSV---------IIGGLF 805
Query: 911 PYSNYKLEMVVVNGRGDGPRSE 932
P Y++E+ G G +SE
Sbjct: 806 PGIQYRVEVAASTSAGVGVKSE 827
Score = 186 bits (471), Expect = 1e-46
Identities = 152/514 (29%), Positives = 218/514 (42%), Gaps = 52/514 (10%)
Query: 34 PPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRR--SG 91
PP I + + D IV + + C+A+G P P+ W ++ KD S R SG
Sbjct: 30 PPRIVEHPS-DVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSG 88
Query: 92 TLV-IDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGA 150
+L + G R + EG Y C ARN G A+S L+V+ ++N VVV G
Sbjct: 89 SLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGE 148
Query: 151 PLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNAR 210
P L+C PP G P P I+W + +++R+S G L SN D Y+C
Sbjct: 149 PAILECQPPRGHPEPTIYWKKDKVRIDDKEERISI-RGGKLMISNTRKSDAGM-YTC--- 203
Query: 211 FHFTHTIQQKNPFTLKVLTNHPYNDSSLRNHPDMYSARGVAERTPSFMYPQGTASSQMVL 270
V TN + D A P+F+ +Q+VL
Sbjct: 204 ----------------VGTN-------MVGERDSDPAELTVFERPTFL---RRPINQVVL 237
Query: 271 RGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLAS 330
+ C G P P + W K DLP + ++ + LRI D G Y C+A
Sbjct: 238 EEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKD-DYTLRIKKTMSTDEGTYMCIAE 296
Query: 331 NKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGE---- 386
N++G + + ++ V+A P ++ P++ I+A G C GNP+P V W G
Sbjct: 297 NRVGKMEASATLTVRAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLL 356
Query: 387 -PLQSAPPNPNREVA--GDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDV---- 439
P Q PN V+ GD I + Q S Y C G +LA A + V DV
Sbjct: 357 FPNQPQQPNSRCSVSPTGDLTI-TNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDR 415
Query: 440 -PPRML-SPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSL 497
PP +L P NQ + V L C G P+P + W K G + E G+L
Sbjct: 416 PPPIILQGPANQTLAV--DGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQGTL 473
Query: 498 EIKMIRKEDQGIYTCVATNILGKAENQVRLEVKD 531
+IK +R D G YTCVAT+ G+ L+V +
Sbjct: 474 QIKNLRISDTGTYTCVATSSSGETSWSAVLDVTE 507
Score = 161 bits (407), Expect = 4e-39
Identities = 222/894 (24%), Positives = 358/894 (40%), Gaps = 115/894 (12%)
Query: 265 SSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNV------- 317
S +V +G L C A G PTP I WYK G + +DK + L ++
Sbjct: 38 SDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVH 97
Query: 318 ---SEEDSGEYFCLASNKMG-SIRHTISVRVKAA-PYWLDEPKNLILAPGEDGRLVCRA- 371
S+ D G Y C+A N +G ++ S+ V + P ++++A GE L C+
Sbjct: 98 GRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPP 157
Query: 372 NGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLAN 431
G+P+PT+ W + ++ + G ++ +T+ S +Y C +N G ++
Sbjct: 158 RGHPEPTIYW--KKDKVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSD 215
Query: 432 -AFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYH 490
A ++V + P + P NQ+ V+ C G P PT+RW K+ ++L G Y
Sbjct: 216 PAELTVFERPTFLRRPINQV--VLEEEAVEFRCQVQGDPQPTVRWKKDD--ADLPRGRYD 271
Query: 491 VYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTV 550
+ ++ +L IK D+G Y C+A N +GK E L V+ P + P DQ+ +G TV
Sbjct: 272 IKDDYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQFVVRPRDQIVAQGRTV 331
Query: 551 QLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDS---------LTIFGVAERDQGSY 601
C K +P + V W K+ + ++ +S LTI + D G Y
Sbjct: 332 TFPCETKGNP--QPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYY 389
Query: 602 TCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERSVRL---T 658
C A T LAKA L V D T DRP + L A +++ +
Sbjct: 390 ICQALTVAGSILAKAQLEV-TDVLT-------------DRPPPIILQGPANQTLAVDGTA 435
Query: 659 WIPGDANNSPITDYVVQFEEDQFQ-PGVWHDHS-KYPGSVNSAVLRLSPYVNY------- 709
+ A P+ V+ + ++ F PG + + G++ LR+S Y
Sbjct: 436 LLKCKATGDPLP--VISWLKEGFTFPGRDPRATIQEQGTLQIKNLRISDTGTYTCVATSS 493
Query: 710 --QFRVIAINEVGSSHPSLPSERYRTSGAP-PESNPGDVKGEGTRKNNMEITWTPMNATS 766
+ A+ +V S ++ S+ Y S P P S P + KN++ ++W P T
Sbjct: 494 SGETSWSAVLDVTESGATI-SKNYDLSDLPGPPSKP---QVTDVTKNSVTLSWQP--GTP 547
Query: 767 AFGPNLRYIVKWRRRETREAWNNVT--VWGSRYVVGQTPVYVPYEIRVQAENDFG-KGPE 823
P YI++ + +W V V + Y V Y V+A N G P
Sbjct: 548 GTLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLRPNTIYLFMVRAINPQGLSDPS 607
Query: 824 PESVIGYSGEDYPRAAPTE----------VKVR-----VMNSTAISLQWNRVYSDTVQGQ 868
P S + + P A + V VR V+ T + + W D
Sbjct: 608 PMSDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNPVVLTPTTVQVTWT---VDRQPQF 664
Query: 869 LREYRAYYWRESSLLKNLWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDG 928
++ YR Y + S L S + A P +R V+ L Y++++ G
Sbjct: 665 IQGYRVMYRQTSGLQATS--SWQNLDAKVPTER-SAVLVNLKKGVTYEIKVRPYFNEFQG 721
Query: 929 PRSETKEFTTPEGVPSAPRR----FRVRQPNLETINLEWD--HPEHPNGIMIGYTLKYVA 982
SE+K T E PSAP + V N +I++ WD P+H NGI+ Y + +
Sbjct: 722 MDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPDHQNGIIQEYKIWCL- 780
Query: 983 FNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESPAP----- 1037
G + I + + P +YR ++A T G G + P P
Sbjct: 781 --GNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVG---VKSEPQPIIIGR 835
Query: 1038 PNEATPTA---AYTNNQADIATQGWF---IGLMCAIALLVLILLIVCFIKRSRG 1085
NE T + T D+ Q F IG C + L+ + + K+ +G
Sbjct: 836 RNEVVITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKKRKG 889
Score = 72.8 bits (177), Expect = 2e-12
Identities = 76/322 (23%), Positives = 124/322 (38%), Gaps = 57/322 (17%)
Query: 28 PMDLT--QPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSR-----FFNIAK 80
P +LT + PT ++ +++ + + C+ +G+P P+ W ++ ++I
Sbjct: 216 PAELTVFERPTFLRRPINQVVLE-EEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKD 274
Query: 81 DPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKEN 140
D + +++ T EG Y C A N+ G + L V P +
Sbjct: 275 DYTLRIKKTMST-------------DEGTYMCIAENRVG-KMEASATLTVRAPPQFVVRP 320
Query: 141 LDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSM-------EPITQDKRVSQGHNGDLYF 193
D +V Q G +T C G P P +FW +P + R S GDL
Sbjct: 321 RDQIVAQ-GRTVTFPCE-TKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTI 378
Query: 194 SNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRNHPDMYSARGVAER 253
+N+ D Y C A + + VLT+ P
Sbjct: 379 TNIQRSDAGY-YICQALTVAGSILAKAQLEVTDVLTDRP--------------------- 416
Query: 254 TPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPS-DKAKFENFNKAL 312
P + QG A+ + + G LL+C A+G P P I+W K+G P D L
Sbjct: 417 PPIIL--QGPANQTLAVDG-TALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQGTL 473
Query: 313 RITNVSEEDSGEYFCLASNKMG 334
+I N+ D+G Y C+A++ G
Sbjct: 474 QIKNLRISDTGTYTCVATSSSG 495
Score = 37.0 bits (84), Expect = 0.11
Identities = 34/139 (24%), Positives = 61/139 (43%), Gaps = 15/139 (10%)
Query: 12 AAFLLC-LLSLGGAI------EIPMDLT-QPPTITKQSAKDHIVDPRDNILIECEAKGNP 63
A + +C L++ G+I E+ LT +PP I Q + + L++C+A G+P
Sbjct: 386 AGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDP 445
Query: 64 APSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALS 123
P W + F +DPR +++ + + + R G Y C A + G
Sbjct: 446 LPVISWLKEGFTFP-GRDPRATIQEQGTLQIKNLRISD-----TGTYTCVATSSSGETSW 499
Query: 124 NRIRLQVSKSPLWPKENLD 142
+ + L V++S +N D
Sbjct: 500 SAV-LDVTESGATISKNYD 517
>gi|19743806 roundabout 1 isoform b [Homo sapiens]
Length = 1612
Score = 187 bits (476), Expect = 4e-47
Identities = 210/860 (24%), Positives = 326/860 (37%), Gaps = 108/860 (12%)
Query: 127 RLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQG 186
RL+ P E+ ++V +G P TL C G P+P I W E + DK +
Sbjct: 21 RLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAE-GRPTPTIEWYKGG-ERVETDKDDPRS 78
Query: 187 H-----NGDLYFSNVM----LQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSS 237
H +G L+F ++ + + Y C AR + + + +L +
Sbjct: 79 HRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRD------D 132
Query: 238 LRNHPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIAS-GVPTPDIAWYKKGG 296
R +P S MV G ++EC G P P I+W K G
Sbjct: 133 FRQNP----------------------SDVMVAVGEPAVMECQPPRGHPEPTISWKKDGS 170
Query: 297 DLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTIS-VRVKAAPYWLDEPK 355
L + L IT + D+G+Y C+ +N +G ++ + V P ++ P
Sbjct: 171 PLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPS 230
Query: 356 NLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGD-TIIFRDTQISSR 414
NL + + C A G+P PTV+W + L P E+ D T+ R
Sbjct: 231 NLAVTVDDSAEFKCEARGDPVPTVRWRKDDGEL----PKSRYEIRDDHTLKIRKVTAGDM 286
Query: 415 AVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLR 474
Y C N G A+A ++V + P ++ PR+Q+ V L C G+P P +
Sbjct: 287 GSYTCVAENMVGKAEASATLTVQEPPHFVVKPRDQV--VALGRTVTFQCEATGNPQPAIF 344
Query: 475 WFKNGQGSNL-------DGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRL 527
W + G + L + V + G L I +++ D G Y C N+ G + L
Sbjct: 345 WRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYL 404
Query: 528 EVKD------PTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYI-GNR 580
EV D P I + P +Q T L C P T+ W KD + +R
Sbjct: 405 EVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVP--TILWRKDGVLVSTQDSR 462
Query: 581 MKK-EDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRP 639
+K+ E+ L I D G YTC+AST + AY+ V P P
Sbjct: 463 IKQLENGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIP 522
Query: 640 DRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSA 699
P E+TD++ +V L+W P + + T Y+++ W ++ + SA
Sbjct: 523 SAPSKPEVTDVSRNTVTLSWQPNLNSGATPTSYIIE-AFSHASGSSWQTVAENVKTETSA 581
Query: 700 VLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNN----- 754
+ L P Y F V A N G S PS S+ +T P S D K N
Sbjct: 582 IKGLKPNAIYLFLVRAANAYGISDPSQISDPVKTQDVLPTSQGVDHKQVQRELGNAVLHL 641
Query: 755 ----------MEITWTPMNATSAFGPNLRYIVK----------WRRRETREAWNNVTVWG 794
+E+ WT ++ S + + + + W E R N
Sbjct: 642 HNPTVLSSSSIEVHWT-VDQQSQYIQGYKILYRPSGANHGESDWLVFEVRTPAKN----- 695
Query: 795 SRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDYPRAAPTEVKVRVM--NSTA 852
V+ V YEI+ + + +G + E + E+ P A P V V N TA
Sbjct: 696 -SVVIPDLRKGVNYEIKARPFFNEFQGADSEIKFAKTLEEAPSAPPQGVTVSKNDGNGTA 754
Query: 853 ISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQASFPGDRLRGVVSRLFPY 912
I + W DT G ++EY+ + L N ++ + G V+ L P
Sbjct: 755 ILVSWQPPPEDTQNGMVQEYKVW------CLGN--ETRYHINKTVDGSTFSVVIPFLVPG 806
Query: 913 SNYKLEMVVVNGRGDGPRSE 932
Y +E+ G G G +SE
Sbjct: 807 IRYSVEVAASTGAGSGVKSE 826
Score = 169 bits (429), Expect = 1e-41
Identities = 141/514 (27%), Positives = 222/514 (43%), Gaps = 52/514 (10%)
Query: 34 PPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRR--SG 91
PP I + + D IV + + C+A+G P P+ W + KD S R SG
Sbjct: 28 PPRIVEHPS-DLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSG 86
Query: 92 TLV-IDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGA 150
+L + G + EG Y C ARN G A+S+ L+V+ ++N V+V G
Sbjct: 87 SLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGE 146
Query: 151 PLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNAR 210
P ++C PP G P P I W +D+R++ G L + D Y C
Sbjct: 147 PAVMECQPPRGHPEPTISWKKDGSPLDDKDERITI-RGGKLMITYTRKSD-AGKYVCVG- 203
Query: 211 FHFTHTIQQKNPFTLKVLTNHPYNDSSLRNHPDMYSARGVAERTPSFMYPQGTASSQMVL 270
T+ + ++ ++ V ER PSF+ S+ V
Sbjct: 204 ---TNMVGERESEVAELT---------------------VLER-PSFV---KRPSNLAVT 235
Query: 271 RGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLAS 330
+C A G P P + W K G+LP + + + + L+I V+ D G Y C+A
Sbjct: 236 VDDSAEFKCEARGDPVPTVRWRKDDGELPKSRYEIRD-DHTLKIRKVTAGDMGSYTCVAE 294
Query: 331 NKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEP--- 387
N +G + ++ V+ P+++ +P++ ++A G C A GNP+P + W G
Sbjct: 295 NMVGKAEASATLTVQEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLL 354
Query: 388 LQSAPPNPNREVA----GDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDV---- 439
PP + + GD I + Q S Y C T N G ++ A++ V DV
Sbjct: 355 FSYQPPQSSSRFSVSQTGDLTI-TNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADR 413
Query: 440 PPRML--SPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSL 497
PP ++ P NQ + V L C GSP+PT+ W K+G + ENG L
Sbjct: 414 PPPVIRQGPVNQTVAV--DGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVL 471
Query: 498 EIKMIRKEDQGIYTCVATNILGKAENQVRLEVKD 531
+I+ + D G YTC+A+ G+A +EV++
Sbjct: 472 QIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQE 505
Score = 76.3 bits (186), Expect = 2e-13
Identities = 90/370 (24%), Positives = 141/370 (38%), Gaps = 60/370 (16%)
Query: 31 LTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRN-----SRFFNIAKDPRVS 85
L +P + + S VD D+ +CEA+G+P P+ W ++ + I D +
Sbjct: 220 LERPSFVKRPSNLAVTVD--DSAEFKCEARGDPVPTVRWRKDDGELPKSRYEIRDDHTLK 277
Query: 86 MRR-RSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPV 144
+R+ +G + G Y C A N G A ++ L V + P + + D V
Sbjct: 278 IRKVTAGDM--------------GSYTCVAENMVGKAEAS-ATLTVQEPPHFVVKPRDQV 322
Query: 145 VVQEGAPLTLQCNPPPGLPSPVIFW-------MSSSMEPITQDKRVSQGHNGDLYFSNVM 197
V G +T QC G P P IFW + S +P R S GDL +NV
Sbjct: 323 VAL-GRTVTFQCE-ATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQ 380
Query: 198 LQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRNHPDMYSARGVAERTPSF 257
D+ Y C TL V S+ + +A+R P
Sbjct: 381 RSDVGY-YICQ---------------TLNVA-------GSIITKAYLEVTDVIADRPPP- 416
Query: 258 MYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENF-NKALRITN 316
+ QG + + + G +L C+A+G P P I W K G + + ++ + N L+I
Sbjct: 417 VIRQGPVNQTVAVDG-TFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRY 475
Query: 317 VSEEDSGEYFCLASNKMGSIRHTISVRVK--AAPYWLDEPKNLILAPGEDGRLVCRANGN 374
D+G Y C+AS G + + V+ P P + L P +
Sbjct: 476 AKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSR 535
Query: 375 PKPTVQWMVN 384
T+ W N
Sbjct: 536 NTVTLSWQPN 545
Score = 31.2 bits (69), Expect = 6.1
Identities = 21/109 (19%), Positives = 39/109 (35%), Gaps = 2/109 (1%)
Query: 937 TTPEGVPSAPRRFRVRQPNLETINLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVENF 996
T P +PSAP + V + T+ L W + Y ++ + + + EN
Sbjct: 516 TDPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSGATPTSYIIEAFSHASGSSWQTVAENV 575
Query: 997 SPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESPAPPNEATPTA 1045
+ ++ P + Y F + A G + P + PT+
Sbjct: 576 KTETS--AIKGLKPNAIYLFLVRAANAYGISDPSQISDPVKTQDVLPTS 622
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.134 0.406
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,759,206
Number of Sequences: 37866
Number of extensions: 2618382
Number of successful extensions: 17211
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 300
Number of HSP's successfully gapped in prelim test: 235
Number of HSP's that attempted gapping in prelim test: 7081
Number of HSP's gapped (non-prelim): 5001
length of query: 1189
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1076
effective length of database: 13,968,660
effective search space: 15030278160
effective search space used: 15030278160
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.