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Search of human proteins with 116174789
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|116174789 centrosome spindle pole associated protein 1
isoform a [Homo sapiens]
(1256 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|116174789 centrosome spindle pole associated protein 1 isofor... 2503 0.0
gi|116174778 centrosome spindle pole associated protein 1 isofor... 2419 0.0
gi|148746195 trichohyalin [Homo sapiens] 92 3e-18
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 84 1e-15
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 81 5e-15
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 78 5e-14
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 77 1e-13
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 76 2e-13
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 74 9e-13
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 73 2e-12
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 73 2e-12
gi|239735584 TRAF2 and NCK interacting kinase isoform 4 [Homo sa... 70 1e-11
gi|239735582 TRAF2 and NCK interacting kinase isoform 3 [Homo sa... 70 1e-11
gi|221219020 NYD-SP11 protein [Homo sapiens] 69 3e-11
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 69 4e-11
gi|4506467 radixin [Homo sapiens] 69 4e-11
gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo sa... 68 5e-11
gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo sa... 68 5e-11
gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo sa... 68 6e-11
gi|55741807 TRAF2 and NCK interacting kinase isoform 1 [Homo sap... 68 6e-11
gi|62244004 modulator of estrogen induced transcription isoform ... 67 8e-11
gi|63176611 modulator of estrogen induced transcription isoform ... 67 8e-11
gi|22035606 mitogen-activated protein kinase kinase kinase kinas... 67 1e-10
gi|22035602 mitogen-activated protein kinase kinase kinase kinas... 67 1e-10
gi|22035604 mitogen-activated protein kinase kinase kinase kinas... 67 1e-10
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 67 1e-10
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 67 1e-10
gi|120953300 leucine-rich repeats and IQ motif containing 1 isof... 66 2e-10
gi|120953243 leucine-rich repeats and IQ motif containing 1 isof... 66 2e-10
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 65 3e-10
>gi|116174789 centrosome spindle pole associated protein 1 isoform a
[Homo sapiens]
Length = 1256
Score = 2503 bits (6487), Expect = 0.0
Identities = 1256/1256 (100%), Positives = 1256/1256 (100%)
Query: 1 MLFPLQVAAVTSSVRDDPLEHCVSPRTRARSPEICKMADNLDEFIEEQKARLAEDKAELE 60
MLFPLQVAAVTSSVRDDPLEHCVSPRTRARSPEICKMADNLDEFIEEQKARLAEDKAELE
Sbjct: 1 MLFPLQVAAVTSSVRDDPLEHCVSPRTRARSPEICKMADNLDEFIEEQKARLAEDKAELE 60
Query: 61 SDPPYMEMKGKLSAKLSENSKILISMAKENIPPNSQQTRGSLGIDYGLSLPLGEDYERKK 120
SDPPYMEMKGKLSAKLSENSKILISMAKENIPPNSQQTRGSLGIDYGLSLPLGEDYERKK
Sbjct: 61 SDPPYMEMKGKLSAKLSENSKILISMAKENIPPNSQQTRGSLGIDYGLSLPLGEDYERKK 120
Query: 121 HKLKEELRQDYRRYLTQGITQGKRKKNFLSTSETDPSTLGVSLPIGERLSAKERLKLERN 180
HKLKEELRQDYRRYLTQGITQGKRKKNFLSTSETDPSTLGVSLPIGERLSAKERLKLERN
Sbjct: 121 HKLKEELRQDYRRYLTQGITQGKRKKNFLSTSETDPSTLGVSLPIGERLSAKERLKLERN 180
Query: 181 KEYNQFLRGKEESSEKFRQVEKSTEPKSQRNKKPIGQVKPDLTSQIQTSCENSEGPRKDV 240
KEYNQFLRGKEESSEKFRQVEKSTEPKSQRNKKPIGQVKPDLTSQIQTSCENSEGPRKDV
Sbjct: 181 KEYNQFLRGKEESSEKFRQVEKSTEPKSQRNKKPIGQVKPDLTSQIQTSCENSEGPRKDV 240
Query: 241 LTPSEAYEELLNQRRLEEDRYRQLDDEIELRNRRIIKKANEEVGISNLKHQRFASKAGIP 300
LTPSEAYEELLNQRRLEEDRYRQLDDEIELRNRRIIKKANEEVGISNLKHQRFASKAGIP
Sbjct: 241 LTPSEAYEELLNQRRLEEDRYRQLDDEIELRNRRIIKKANEEVGISNLKHQRFASKAGIP 300
Query: 301 DRRFHRFNEDRVFDRRYHRPDQDPEVSEEMDERFRYESDFDRRLSRVYTNDRMHRNKRGN 360
DRRFHRFNEDRVFDRRYHRPDQDPEVSEEMDERFRYESDFDRRLSRVYTNDRMHRNKRGN
Sbjct: 301 DRRFHRFNEDRVFDRRYHRPDQDPEVSEEMDERFRYESDFDRRLSRVYTNDRMHRNKRGN 360
Query: 361 MPPMEHDGDVIEQSNIRISSAENKSAPDNETSKSANQDTCSPFAGMLFGGEDRELIQRRK 420
MPPMEHDGDVIEQSNIRISSAENKSAPDNETSKSANQDTCSPFAGMLFGGEDRELIQRRK
Sbjct: 361 MPPMEHDGDVIEQSNIRISSAENKSAPDNETSKSANQDTCSPFAGMLFGGEDRELIQRRK 420
Query: 421 EKYRLELLEQMAEQQRNKRREKDLELRVAASGAQDPEKSPDRLKQFSVAPRHFEEMIPPE 480
EKYRLELLEQMAEQQRNKRREKDLELRVAASGAQDPEKSPDRLKQFSVAPRHFEEMIPPE
Sbjct: 421 EKYRLELLEQMAEQQRNKRREKDLELRVAASGAQDPEKSPDRLKQFSVAPRHFEEMIPPE 480
Query: 481 RPRIAFQTPLPPLSAPSVPPIPSVHPVPSQNEDLRSGLSSALGEMVSPRIAPLPPPPLLP 540
RPRIAFQTPLPPLSAPSVPPIPSVHPVPSQNEDLRSGLSSALGEMVSPRIAPLPPPPLLP
Sbjct: 481 RPRIAFQTPLPPLSAPSVPPIPSVHPVPSQNEDLRSGLSSALGEMVSPRIAPLPPPPLLP 540
Query: 541 PLATNYRTPYDDAYYFYGSRNTFDPSLAYYGSGMMGVQPAAYVSAPVTHQLAQPVVNTVG 600
PLATNYRTPYDDAYYFYGSRNTFDPSLAYYGSGMMGVQPAAYVSAPVTHQLAQPVVNTVG
Sbjct: 541 PLATNYRTPYDDAYYFYGSRNTFDPSLAYYGSGMMGVQPAAYVSAPVTHQLAQPVVNTVG 600
Query: 601 QNELKITSDQVINSGLIFEDKPKPSKQSLQSYQEALQQQIREREERRKKEREEKEEYEAK 660
QNELKITSDQVINSGLIFEDKPKPSKQSLQSYQEALQQQIREREERRKKEREEKEEYEAK
Sbjct: 601 QNELKITSDQVINSGLIFEDKPKPSKQSLQSYQEALQQQIREREERRKKEREEKEEYEAK 660
Query: 661 LEAEMRTYNPWGKGGGGAPLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLD 720
LEAEMRTYNPWGKGGGGAPLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLD
Sbjct: 661 LEAEMRTYNPWGKGGGGAPLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLD 720
Query: 721 PNLATSNAENLEDAANKSSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEE 780
PNLATSNAENLEDAANKSSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEE
Sbjct: 721 PNLATSNAENLEDAANKSSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEE 780
Query: 781 KKQREEAERERLRIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAE 840
KKQREEAERERLRIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAE
Sbjct: 781 KKQREEAERERLRIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAE 840
Query: 841 ERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPP 900
ERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPP
Sbjct: 841 ERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPP 900
Query: 901 SVDSIIRSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLRSEERRLQER 960
SVDSIIRSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLRSEERRLQER
Sbjct: 901 SVDSIIRSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLRSEERRLQER 960
Query: 961 LLHMDSDDEIPIRKKERNPMDIFDMARHRLQAPVRRQSPKGLDAATFQNVHDFNELKDRD 1020
LLHMDSDDEIPIRKKERNPMDIFDMARHRLQAPVRRQSPKGLDAATFQNVHDFNELKDRD
Sbjct: 961 LLHMDSDDEIPIRKKERNPMDIFDMARHRLQAPVRRQSPKGLDAATFQNVHDFNELKDRD 1020
Query: 1021 SETRVDLKFMYLDPPRDHHTLEIQQQALLREQQKRLNRIKMQEGAKVDLDAIPSAKVREQ 1080
SETRVDLKFMYLDPPRDHHTLEIQQQALLREQQKRLNRIKMQEGAKVDLDAIPSAKVREQ
Sbjct: 1021 SETRVDLKFMYLDPPRDHHTLEIQQQALLREQQKRLNRIKMQEGAKVDLDAIPSAKVREQ 1080
Query: 1081 RMPRDDTSDFLKNSLLESDSAFIGAYGETYPAIEDDVLPPPSQLPSARERRRNKWKGLDI 1140
RMPRDDTSDFLKNSLLESDSAFIGAYGETYPAIEDDVLPPPSQLPSARERRRNKWKGLDI
Sbjct: 1081 RMPRDDTSDFLKNSLLESDSAFIGAYGETYPAIEDDVLPPPSQLPSARERRRNKWKGLDI 1140
Query: 1141 DSSRPNVAPDGLSLKSISSVNVDELRVRNEERMRRLNEFHNKPINTDDESSLVDPDDIMK 1200
DSSRPNVAPDGLSLKSISSVNVDELRVRNEERMRRLNEFHNKPINTDDESSLVDPDDIMK
Sbjct: 1141 DSSRPNVAPDGLSLKSISSVNVDELRVRNEERMRRLNEFHNKPINTDDESSLVDPDDIMK 1200
Query: 1201 HIGDDGSNSVATEPWLRPGTSETLKRFMAEQLNQEQQQIPGKPGTFTWQGLSTAHG 1256
HIGDDGSNSVATEPWLRPGTSETLKRFMAEQLNQEQQQIPGKPGTFTWQGLSTAHG
Sbjct: 1201 HIGDDGSNSVATEPWLRPGTSETLKRFMAEQLNQEQQQIPGKPGTFTWQGLSTAHG 1256
>gi|116174778 centrosome spindle pole associated protein 1 isoform b
[Homo sapiens]
Length = 1221
Score = 2419 bits (6268), Expect = 0.0
Identities = 1221/1256 (97%), Positives = 1221/1256 (97%), Gaps = 35/1256 (2%)
Query: 1 MLFPLQVAAVTSSVRDDPLEHCVSPRTRARSPEICKMADNLDEFIEEQKARLAEDKAELE 60
MLFPLQVAAVTSSVRDDPLEHCVSPRTRARSPEICKMADNLDEFIEEQKARLAEDKAELE
Sbjct: 1 MLFPLQVAAVTSSVRDDPLEHCVSPRTRARSPEICKMADNLDEFIEEQKARLAEDKAELE 60
Query: 61 SDPPYMEMKGKLSAKLSENSKILISMAKENIPPNSQQTRGSLGIDYGLSLPLGEDYERKK 120
SDPPYMEMKGKLSAKLSENSKILISMAKENIPPNSQQTRGSLGIDYGLSLPLGEDYERKK
Sbjct: 61 SDPPYMEMKGKLSAKLSENSKILISMAKENIPPNSQQTRGSLGIDYGLSLPLGEDYERKK 120
Query: 121 HKLKEELRQDYRRYLTQGITQGKRKKNFLSTSETDPSTLGVSLPIGERLSAKERLKLERN 180
HKLKEELRQDYRRYLTQ ERLKLERN
Sbjct: 121 HKLKEELRQDYRRYLTQ-----------------------------------ERLKLERN 145
Query: 181 KEYNQFLRGKEESSEKFRQVEKSTEPKSQRNKKPIGQVKPDLTSQIQTSCENSEGPRKDV 240
KEYNQFLRGKEESSEKFRQVEKSTEPKSQRNKKPIGQVKPDLTSQIQTSCENSEGPRKDV
Sbjct: 146 KEYNQFLRGKEESSEKFRQVEKSTEPKSQRNKKPIGQVKPDLTSQIQTSCENSEGPRKDV 205
Query: 241 LTPSEAYEELLNQRRLEEDRYRQLDDEIELRNRRIIKKANEEVGISNLKHQRFASKAGIP 300
LTPSEAYEELLNQRRLEEDRYRQLDDEIELRNRRIIKKANEEVGISNLKHQRFASKAGIP
Sbjct: 206 LTPSEAYEELLNQRRLEEDRYRQLDDEIELRNRRIIKKANEEVGISNLKHQRFASKAGIP 265
Query: 301 DRRFHRFNEDRVFDRRYHRPDQDPEVSEEMDERFRYESDFDRRLSRVYTNDRMHRNKRGN 360
DRRFHRFNEDRVFDRRYHRPDQDPEVSEEMDERFRYESDFDRRLSRVYTNDRMHRNKRGN
Sbjct: 266 DRRFHRFNEDRVFDRRYHRPDQDPEVSEEMDERFRYESDFDRRLSRVYTNDRMHRNKRGN 325
Query: 361 MPPMEHDGDVIEQSNIRISSAENKSAPDNETSKSANQDTCSPFAGMLFGGEDRELIQRRK 420
MPPMEHDGDVIEQSNIRISSAENKSAPDNETSKSANQDTCSPFAGMLFGGEDRELIQRRK
Sbjct: 326 MPPMEHDGDVIEQSNIRISSAENKSAPDNETSKSANQDTCSPFAGMLFGGEDRELIQRRK 385
Query: 421 EKYRLELLEQMAEQQRNKRREKDLELRVAASGAQDPEKSPDRLKQFSVAPRHFEEMIPPE 480
EKYRLELLEQMAEQQRNKRREKDLELRVAASGAQDPEKSPDRLKQFSVAPRHFEEMIPPE
Sbjct: 386 EKYRLELLEQMAEQQRNKRREKDLELRVAASGAQDPEKSPDRLKQFSVAPRHFEEMIPPE 445
Query: 481 RPRIAFQTPLPPLSAPSVPPIPSVHPVPSQNEDLRSGLSSALGEMVSPRIAPLPPPPLLP 540
RPRIAFQTPLPPLSAPSVPPIPSVHPVPSQNEDLRSGLSSALGEMVSPRIAPLPPPPLLP
Sbjct: 446 RPRIAFQTPLPPLSAPSVPPIPSVHPVPSQNEDLRSGLSSALGEMVSPRIAPLPPPPLLP 505
Query: 541 PLATNYRTPYDDAYYFYGSRNTFDPSLAYYGSGMMGVQPAAYVSAPVTHQLAQPVVNTVG 600
PLATNYRTPYDDAYYFYGSRNTFDPSLAYYGSGMMGVQPAAYVSAPVTHQLAQPVVNTVG
Sbjct: 506 PLATNYRTPYDDAYYFYGSRNTFDPSLAYYGSGMMGVQPAAYVSAPVTHQLAQPVVNTVG 565
Query: 601 QNELKITSDQVINSGLIFEDKPKPSKQSLQSYQEALQQQIREREERRKKEREEKEEYEAK 660
QNELKITSDQVINSGLIFEDKPKPSKQSLQSYQEALQQQIREREERRKKEREEKEEYEAK
Sbjct: 566 QNELKITSDQVINSGLIFEDKPKPSKQSLQSYQEALQQQIREREERRKKEREEKEEYEAK 625
Query: 661 LEAEMRTYNPWGKGGGGAPLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLD 720
LEAEMRTYNPWGKGGGGAPLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLD
Sbjct: 626 LEAEMRTYNPWGKGGGGAPLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLD 685
Query: 721 PNLATSNAENLEDAANKSSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEE 780
PNLATSNAENLEDAANKSSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEE
Sbjct: 686 PNLATSNAENLEDAANKSSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEE 745
Query: 781 KKQREEAERERLRIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAE 840
KKQREEAERERLRIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAE
Sbjct: 746 KKQREEAERERLRIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAE 805
Query: 841 ERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPP 900
ERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPP
Sbjct: 806 ERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPP 865
Query: 901 SVDSIIRSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLRSEERRLQER 960
SVDSIIRSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLRSEERRLQER
Sbjct: 866 SVDSIIRSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLRSEERRLQER 925
Query: 961 LLHMDSDDEIPIRKKERNPMDIFDMARHRLQAPVRRQSPKGLDAATFQNVHDFNELKDRD 1020
LLHMDSDDEIPIRKKERNPMDIFDMARHRLQAPVRRQSPKGLDAATFQNVHDFNELKDRD
Sbjct: 926 LLHMDSDDEIPIRKKERNPMDIFDMARHRLQAPVRRQSPKGLDAATFQNVHDFNELKDRD 985
Query: 1021 SETRVDLKFMYLDPPRDHHTLEIQQQALLREQQKRLNRIKMQEGAKVDLDAIPSAKVREQ 1080
SETRVDLKFMYLDPPRDHHTLEIQQQALLREQQKRLNRIKMQEGAKVDLDAIPSAKVREQ
Sbjct: 986 SETRVDLKFMYLDPPRDHHTLEIQQQALLREQQKRLNRIKMQEGAKVDLDAIPSAKVREQ 1045
Query: 1081 RMPRDDTSDFLKNSLLESDSAFIGAYGETYPAIEDDVLPPPSQLPSARERRRNKWKGLDI 1140
RMPRDDTSDFLKNSLLESDSAFIGAYGETYPAIEDDVLPPPSQLPSARERRRNKWKGLDI
Sbjct: 1046 RMPRDDTSDFLKNSLLESDSAFIGAYGETYPAIEDDVLPPPSQLPSARERRRNKWKGLDI 1105
Query: 1141 DSSRPNVAPDGLSLKSISSVNVDELRVRNEERMRRLNEFHNKPINTDDESSLVDPDDIMK 1200
DSSRPNVAPDGLSLKSISSVNVDELRVRNEERMRRLNEFHNKPINTDDESSLVDPDDIMK
Sbjct: 1106 DSSRPNVAPDGLSLKSISSVNVDELRVRNEERMRRLNEFHNKPINTDDESSLVDPDDIMK 1165
Query: 1201 HIGDDGSNSVATEPWLRPGTSETLKRFMAEQLNQEQQQIPGKPGTFTWQGLSTAHG 1256
HIGDDGSNSVATEPWLRPGTSETLKRFMAEQLNQEQQQIPGKPGTFTWQGLSTAHG
Sbjct: 1166 HIGDDGSNSVATEPWLRPGTSETLKRFMAEQLNQEQQQIPGKPGTFTWQGLSTAHG 1221
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 92.0 bits (227), Expect = 3e-18
Identities = 110/478 (23%), Positives = 210/478 (43%), Gaps = 74/478 (15%)
Query: 633 QEALQQQIREREERRKKEREEKEEYEA-----KLEAEMRTYNPWGKGGGGAPLRDAKGNL 687
+E QQQ RER++R +E EEKE + K E +++ P + L++ +
Sbjct: 223 REEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQ----RELQEEE--- 275
Query: 688 ITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAANKSSGHMQTQSS 747
L ++ RQ + + + + R L E E+ + Q +
Sbjct: 276 -EQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEE- 333
Query: 748 PFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERRLAEQR 807
+L+ +Q+E + LR + EE+++ ++ RE+ E++ RR EQ+
Sbjct: 334 ---------RREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRR--EQQ 382
Query: 808 ARIQQEYEEEQEKKREKE--EEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYC 865
R +Q+ EQ+ +RE++ EQ+L+ E+ +R ++ ++E + ++++EEE++ + +
Sbjct: 383 LRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQER 442
Query: 866 ERDNLIGEETKH---MRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQSPP 922
L E+ + +++ Q + +L+R + R E R Q
Sbjct: 443 REQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQ-- 500
Query: 923 VPARKNQLRAEEEKKNVIMELSEMRKQLRSEERRLQERLLHMDSDDEIPIRKKERNPMDI 982
R+ QLR E+E++ E R + + EE RLQ+RL S+ ++ ++ER +
Sbjct: 501 -ERREQQLRREQEERR------EQRLKRQEEEERLQQRL---RSEQQLRREQEERREQLL 550
Query: 983 FDMARHRLQAPVRRQSPKGLDAATFQNVHDFNELKDRDSETRVDLKFMYLDPPRDHHTLE 1042
RL+ R Q K R+ E R D + E
Sbjct: 551 KREEEKRLEQERREQRLK------------------REQEERRDQLLKREE--------E 584
Query: 1043 IQQQALLREQQKRL-NRIKMQEGAKVDLDAIPSAKVREQRMPRDDTSDFLKNSLLESD 1099
+QQ L REQ++RL R+K +E ++ + + REQR+ R++ + + LL+S+
Sbjct: 585 RRQQRLKREQEERLEQRLKREE-----VERLEQEERREQRLKREEPEEERRQQLLKSE 637
Score = 82.0 bits (201), Expect = 3e-15
Identities = 120/576 (20%), Positives = 226/576 (39%), Gaps = 69/576 (11%)
Query: 619 EDKPKPSKQSLQSYQEALQQQIREREERRKKEREEKEEYEAKLEAEMRTYNPWGKGGGGA 678
E++ + ++ + QE +QQ RE++ ++E+EE+ E + + E E +
Sbjct: 311 EEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEE 370
Query: 679 PLRDAKGNLITDLNRMH--RQNIDAYHNPDARTYEDKRAVVSL--------DPNLATSNA 728
R+ + L R R+ R + R L + L
Sbjct: 371 ERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQE 430
Query: 729 ENLEDAANKSSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLR-----------FQ 777
E + ++ Q + + E + +QE K L+ +
Sbjct: 431 EERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLK 490
Query: 778 IEEKKQREEAERERLRIAEEKEERR-----LAEQRARIQQEYEEEQEKKREKEE--EQRL 830
+EE+++RE+ ER ++ E+EERR E+ R+QQ EQ+ +RE+EE EQ L
Sbjct: 491 LEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLL 550
Query: 831 KNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCER--------------DNLIGEETK 876
K EE RL +ER++ +R K+E+EE+ + L+ ER L EE +
Sbjct: 551 KREEEKRLEQERRE--QRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVE 608
Query: 877 HMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPARKNQLRAEEEK 936
+ Q L+ + + +R + S + + + R Q R+ +L+ EEE+
Sbjct: 609 RLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQ---ERREQRLKREEEE 665
Query: 937 KNVIMEL-----SEMRKQLRSEERRLQER----------LLHMDSDDEIPIRKKERNPMD 981
+ + L E R+Q +EE + Q R ++S+ + K P
Sbjct: 666 ERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRK 725
Query: 982 IFDMARHRLQAPVRRQSPKGLDAATFQNVHDFNELKDRDSETRVDLKFMY-LDPPRDHHT 1040
R + Q RR+ L + H + ++ E R D + + + +
Sbjct: 726 QEGQRRRQEQEEKRRRRESELQWQEEERAH----RQQQEEEQRRDFTWQWQAEEKSERGR 781
Query: 1041 LEIQQQALLREQQKRLNRIKMQEGAKVDLDAIPSAKVREQRMPRDDTSDFLKNSLLESDS 1100
+ + LREQ++R +++ +E + + +P + +EQR + + L E +
Sbjct: 782 QRLSARPPLREQRER--QLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQ 839
Query: 1101 AFIGAYGETYPAIEDDVLPPPSQLPSARERRRNKWK 1136
+ ED + + S +RR KW+
Sbjct: 840 LQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWR 875
Score = 79.7 bits (195), Expect = 2e-14
Identities = 110/537 (20%), Positives = 236/537 (43%), Gaps = 88/537 (16%)
Query: 619 EDKPKPSKQSLQSYQEALQQQIREREERRKKEREEKEEYEAKLEAEMRTYNPWGKGGGGA 678
+++ + +Q LQ +E LQ++ RE+ R+++ER+ +EE + + E E
Sbjct: 896 QEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQL------------ 943
Query: 679 PLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAANKS 738
LR+ + + RQ + + D + + + ++ +P + +
Sbjct: 944 -LREER-------EKRRRQERERQYRKDKKLQQKEEQLLGEEPE---KRRRQEREKKYRE 992
Query: 739 SGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEK 798
+Q + R E + ++++ ++ Q +K + ++ E + LR EE+
Sbjct: 993 EEELQQEEEQLLR--------EEREKRRRQEWER----QYRKKDELQQEEEQLLR--EER 1038
Query: 799 EERRLAEQRARIQQEYEEEQEKKR----EKEEEQRLKNEEHIRLAEERQKEAERKKKEEE 854
E+RRL E+ + ++E E +QE+++ E+E +R + E R EE Q+E E+ +EE
Sbjct: 1039 EKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEP 1098
Query: 855 EKYNLQ-LQHYC-ERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHE 912
EK Q + C E + L EE + +R+ + + +L+R + ++ E
Sbjct: 1099 EKRRRQERERQCREEEELQQEEEQLLREER------EKRRRQELERQYREEEEVQQ--EE 1150
Query: 913 SSMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQL--RSEERRLQERLLHMDSDDEI 970
+ R + P R+ +L + ++ EL + +QL +E+R QER ++E+
Sbjct: 1151 EQLLREE--PEKRRRQELERQYREEE---ELQQEEEQLLREEQEKRRQERERQYREEEEL 1205
Query: 971 PIRKKERNPMDIFDMARHRLQAPVRRQSP--------KGLDAATFQNVHDFNELKDRDSE 1022
+K+++ D + + Q +++ KG + F+ + D ++L+DR S+
Sbjct: 1206 QRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLED-SQLRDRQSQ 1264
Query: 1023 TRVDLKFM---YLDPPRDHHTLEIQQQALLREQQKRLNRIKMQEGAKVDLDAIPSAKVRE 1079
DL+ + + R+ QQ+ ++++L R + +E + D E
Sbjct: 1265 Q--DLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRD-----RKSQEE 1317
Query: 1080 QRMPRDDTSDFLKNSLLESDSAFIGAYGETYPAIEDDVLPPPSQLPSARERRRNKWK 1136
+++ R++ + K E+D F E+ +L + P R+ R K++
Sbjct: 1318 KQLLREEREE--KRRRQETDRKF---------REEEQLLQEREEQPLRRQERDRKFR 1363
Score = 77.0 bits (188), Expect = 1e-13
Identities = 102/496 (20%), Positives = 203/496 (40%), Gaps = 91/496 (18%)
Query: 633 QEALQQQIREREERRKKEREEKEEYEAKLEAEMRTYNPWGKGGGGAPLRDAKGNLITDLN 692
+ LQ Q ER R+++E E++ ++ + +AE ++ + PLR+ + L
Sbjct: 743 ESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRER---QLR 799
Query: 693 RMHRQNIDAYHNPDARTYEDKRA--------VVSLDPNLATSNAENLEDAANKSSGHMQT 744
RQ + P+ E +R + L+ E + + G +
Sbjct: 800 AEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQED 859
Query: 745 QSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQR------------EEAERERL 792
Q E + Q++ R+Q+EE+++R E+ +E+
Sbjct: 860 Q---------------ERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQ 904
Query: 793 RIAEEKEE--RRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKE----- 845
+ EE+EE R E+R R +QE + +E++ ++EEEQ L+ E R +ER+++
Sbjct: 905 LLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDK 964
Query: 846 --------------AERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNK 891
+R+++E E+KY + + E + L+ EE + R+ + +
Sbjct: 965 KLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQE-----WERQ 1019
Query: 892 IASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLR 951
K + + ++R E R Q R+ Q R EE EL + +QL
Sbjct: 1020 YRKKDELQQEEEQLLR---EEREKRRLQE-----RERQYREEE-------ELQQEEEQLL 1064
Query: 952 SEERRLQERLLHMDSDDEIPIRKKERNPMDIFDMARHRLQAPVRRQSPKGL-DAATFQNV 1010
EER + R + E RK+E + + R + R++ + + Q
Sbjct: 1065 GEERETRRR-----QELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQE 1119
Query: 1011 HDFNELKDRDSETRVDLKFMYLDPPRDHHTLEIQQQALLRE--QQKRLNRIKMQEGAKVD 1068
+ ++R+ R +L+ Y R+ ++ +++ LLRE +++R ++ Q + +
Sbjct: 1120 EEQLLREEREKRRRQELERQY----REEEEVQQEEEQLLREEPEKRRRQELERQYREEEE 1175
Query: 1069 LDAIPSAKVREQRMPR 1084
L +RE++ R
Sbjct: 1176 LQQEEEQLLREEQEKR 1191
Score = 75.9 bits (185), Expect = 2e-13
Identities = 137/645 (21%), Positives = 253/645 (39%), Gaps = 89/645 (13%)
Query: 619 EDKPKPSKQSLQSYQEAL---QQQIREREERRKKEREEKEEYEAKLEAEMRTYNPWGKGG 675
ED +QS Q Q L Q++ RE+E RR ++R+ E +LE E +
Sbjct: 1254 EDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKE------- 1306
Query: 676 GGAPLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAA 735
A RD K L R R+ D + E+++ L E
Sbjct: 1307 --AKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQ--------LLQEREEQPLRRQ 1356
Query: 736 NKSSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIA 795
+ + + +G F E E ++++QE + FL+ + + + Q E + + R
Sbjct: 1357 ERDRKFREEELRHQEQGRKFLEE--EQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDR 1414
Query: 796 EEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEE 855
+ +EE + ++ R ++ EEEQ+ +R++ E + L+ E+ +R R+ E + +E E
Sbjct: 1415 KFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQERE 1474
Query: 856 KYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSM 915
+ L H ERD EE + +R+ + ++ S Q P R F+ E
Sbjct: 1475 EQQL---HRQERDRKFLEEEQQLRRQERDRKFREQELRS--QEPE------RKFLEE--- 1520
Query: 916 SRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLRSEERRLQERLLHMDSDDEIPIRKK 975
+ QL ++ ++ + E ++R+Q R ++RR Q+R ++++ ++
Sbjct: 1521 -----------EQQLHRQQRQRKFLQEEQQLRRQERGQQRR-QDRDRKFREEEQL---RQ 1565
Query: 976 ERNPMDIFDMARHRL----QAPVRRQSPKGL---DAATFQNVHDFNELK-DRDSETRVDL 1027
ER + R R + VRRQ + D + +L+ +RD + R D
Sbjct: 1566 EREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDE 1625
Query: 1028 KFMYLDPPRDHHTLEIQQQAL---------LREQQKRLNRIKMQEGAKVDLDAIPSAKVR 1078
+ + + H E ++ L REQQ R +R + + L ++R
Sbjct: 1626 QLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLR 1685
Query: 1079 EQRMPRDDTSDFLKNSLLESDSAFIGAYGETYPAIEDDVLPPPSQLPSARE----RRRNK 1134
Q R + + E + F+ + + QL E RR+ +
Sbjct: 1686 RQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQER 1745
Query: 1135 W-KGLDIDSSRPNVAPDGLSLKSISSVNVDELRVRNEERMRRLNEFHNKPINTDDESSLV 1193
+ K L+ + RP +E ++R +ER R+ E + +E L
Sbjct: 1746 YRKILEEEQLRP---------------EREEQQLRRQERDRKFRE-EEQLRQEREEQQLR 1789
Query: 1194 DPDDIMKHIGDDGSNSVATEPWLRPGTSETLKRFMAEQLNQEQQQ 1238
+ K ++ E LRP + R+ EQL E+Q+
Sbjct: 1790 SQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQE 1834
Score = 68.9 bits (167), Expect = 3e-11
Identities = 94/441 (21%), Positives = 199/441 (45%), Gaps = 68/441 (15%)
Query: 636 LQQQIREREERRKKEREEKEEYEAKLEAEMRTYNPWGKGGGGAPLRDAKGNLITDLNRMH 695
L+++ + R+ER +K REE++ + + E ++ RD K + + ++
Sbjct: 1449 LEEEQQLRQERHRKFREEEQLLQEREEQQLHRQE-----------RDRK--FLEEEQQLR 1495
Query: 696 RQNIDA-YHNPDARTYEDKRAVVSLDPNLATSNAENLEDAANKSSGHMQTQSSPFARGNV 754
RQ D + + R+ E +R + + L H Q + F +
Sbjct: 1496 RQERDRKFREQELRSQEPERKFLEEEQQL-----------------HRQQRQRKFLQ--- 1535
Query: 755 FGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERRLAEQRARIQQEY 814
E Q+++QE + R Q ++K REE E+LR +E+EE++L+ Q R ++
Sbjct: 1536 -----EEQQLRRQE--RGQQRRQDRDRKFREE---EQLR--QEREEQQLSRQE-RDRKFR 1582
Query: 815 EEEQEKKREKEEEQRLKNEEHIRLAEERQK---EAERKKKEEEE---KYNLQLQHYCERD 868
EEQ+ +R+++E + +++E+ +R E +Q+ E +RK +E+E+ + Q H ERD
Sbjct: 1583 LEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERD 1642
Query: 869 NLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPARKN 928
EE +R+ L++ K + + +++ + + + +
Sbjct: 1643 RKFLEEEPQLRRQER-EQQLRHDRDRKFREE---EQLLQEGEEQQLRRQERDRKFREEEQ 1698
Query: 929 QLRAEEEKKNVIMELSEMRKQLRSEERRLQERLLHMDSDDEIPIRKKERNPMDIFDMARH 988
QLR +E ++ + E ++R+Q + R +E+L +++ +++ R ++ +
Sbjct: 1699 QLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPE 1758
Query: 989 RLQAPVRRQ--SPKGLDAATFQNVHDFNELKDRDS--------ETRVDLKFMYLDP-PRD 1037
R + +RRQ K + + + +L+ ++S + R + + L P RD
Sbjct: 1759 REEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRD 1818
Query: 1038 HHTLEIQQQALLREQQKRLNR 1058
++Q L EQ++RL +
Sbjct: 1819 GKYRWEEEQLQLEEQEQRLRQ 1839
Score = 68.6 bits (166), Expect = 4e-11
Identities = 113/559 (20%), Positives = 221/559 (39%), Gaps = 114/559 (20%)
Query: 616 LIFEDKPKPSKQSLQ-SYQEALQQQIREREERRKKEREEKEEYEAKLEAEMRTYNPWGKG 674
L+ E+ K +Q L+ Y+E ++++++ EE+ +E +EK E
Sbjct: 1153 LLREEPEKRRRQELERQYRE--EEELQQEEEQLLREEQEKRRQE---------------- 1194
Query: 675 GGGAPLRDAKGNLITDLNRMHRQNIDAYHNPDART-----YEDKRAVVSLDPNLATSNAE 729
R+ + +L R R+ Y + D R+ +E ++ D + E
Sbjct: 1195 ------RERQYREEEELQRQKRK--QRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRE 1246
Query: 730 NLEDAANKSSGHMQTQSSPFARGNVFGEP-------------------PTELQIKQQEL- 769
N E ++ + S ++ GE P E Q++++E
Sbjct: 1247 N-EQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQK 1305
Query: 770 -----------YKNFLRFQIEEKKQREEAE---RERLRIAEEKEE---------RRLAEQ 806
K LR + EEK++R+E + RE ++ +E+EE R+ E+
Sbjct: 1306 EAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREE 1365
Query: 807 RARIQQE----YEEEQEKKREKEEEQRLKNEEHIRLAEERQ---KEAERKKKEEEEKYNL 859
R Q++ EEEQ +R++ E + LK E+ +R E Q ++ +RK +EEE++ +
Sbjct: 1366 ELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSR 1425
Query: 860 QLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSV---DSII---------- 906
Q ERD EE + +R+ L+ + + +R + ++
Sbjct: 1426 Q-----ERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHR 1480
Query: 907 ----RSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLRSEERRLQERLL 962
R F+ E R Q R+ +LR++E ++ + E ++ +Q R + +E+ L
Sbjct: 1481 QERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQL 1540
Query: 963 HMDSDDEIPIRKKERNPMDIFDMARHRLQAPVRRQSPK---GLDAATFQNVHDFNELKDR 1019
+ + ++R + + + R + + RQ L+ + + +
Sbjct: 1541 RRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMED 1600
Query: 1020 DSETRVDLKFMYLDPPRDHHTLEIQQQALLREQQKRLNRIKMQEGAKVDLDAIPSAK--V 1077
+ + R L RD E +Q RE+Q ++ QE + L+ P +
Sbjct: 1601 EQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQ----QLHRQERDRKFLEEEPQLRRQE 1656
Query: 1078 REQRMPRDDTSDFLKNSLL 1096
REQ++ D F + L
Sbjct: 1657 REQQLRHDRDRKFREEEQL 1675
Score = 61.6 bits (148), Expect = 4e-09
Identities = 75/366 (20%), Positives = 152/366 (41%), Gaps = 31/366 (8%)
Query: 618 FEDKPKPSKQSLQSYQEALQQQIREREERRKKEREEKEEYEAKLEAEMRTYNPWGKGGGG 677
F ++ S++ + + E QQ R++R++K +E+++ + + R + K
Sbjct: 1503 FREQELRSQEPERKFLEEEQQL--HRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREE 1560
Query: 678 APLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAANK 737
LR + L+R R R E +R + + L +
Sbjct: 1561 EQLRQEREE--QQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQL----- 1613
Query: 738 SSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEE 797
Q + F + E Q+ +QE + FL + + ++Q E + R +
Sbjct: 1614 ----RQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKF 1669
Query: 798 KEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEE---RQKEAERKKKEEE 854
+EE +L ++ Q +E K RE+E++ R + E L EE R++E ERK +EEE
Sbjct: 1670 REEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEE 1729
Query: 855 EKYNLQLQHYCERDNLIGEET-KHMRQPSPIVPALQNKIASKLQRPPSV--DSIIRSFIH 911
QL+ E++ L +E + + + + P + + + +R + +R
Sbjct: 1730 -----QLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQERE 1784
Query: 912 ESSMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLRSEERRLQERLLHMDSDDEIP 971
E + +S + QLR E E++ ++R Q R + R +E L ++ ++
Sbjct: 1785 EQQLRSQESDRKFREEEQLRQEREEQ-------QLRPQQRDGKYRWEEEQLQLEEQEQRL 1837
Query: 972 IRKKER 977
++++R
Sbjct: 1838 RQERDR 1843
Score = 59.7 bits (143), Expect = 2e-08
Identities = 64/250 (25%), Positives = 110/250 (44%), Gaps = 24/250 (9%)
Query: 620 DKPKPSKQSLQSYQEALQQQIREREERRKKEREE----KEEYEAKL---EAEMRTYNPWG 672
D+ + ++ Q QE +QQ+R +E RK EE ++E E K E ++R
Sbjct: 1664 DRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELER 1723
Query: 673 KGGGGAPLRDAKGNLITDLNRMHRQNI--DAYHNPDARTYEDKRAVVSLDPNLATSNAEN 730
K LR T+ ++ RQ R +++ + + + E
Sbjct: 1724 KFREEEQLRQE-----TEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQ 1778
Query: 731 LEDAANKSSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFL----RFQIEEKKQREE 786
L + Q F + E Q++ Q+ + + Q+EE++QR
Sbjct: 1779 LRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLR 1838
Query: 787 AERERLRIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEA 846
ER+R AEE+ + E+ R +QE +E+E+KR +E E++L+ EEHIR +QKE
Sbjct: 1839 QERDRQYRAEEQFATQ--EKSRREEQELWQEEEQKRRQERERKLR-EEHIR---RQQKEE 1892
Query: 847 ERKKKEEEEK 856
+R ++ E K
Sbjct: 1893 QRHRQVGEIK 1902
Score = 59.3 bits (142), Expect = 2e-08
Identities = 84/409 (20%), Positives = 161/409 (39%), Gaps = 62/409 (15%)
Query: 706 DARTYEDKRAVVSLDPNLATSNAENLEDAANKSSGHMQTQSSPFARGNVFGEPPTEL--- 762
D R ED+R D L E+ + Q Q A G E L
Sbjct: 112 DRRQEEDQRRFEPRDRQLE-------EEPGQRRRQKRQEQERELAEGEEQSEKQERLEQR 164
Query: 763 --QIKQQELYKNFLRFQIEEKKQREEAE--------------------RERLRIAEEKEE 800
Q + +EL++ +Q E+++ EE + RE L + + E
Sbjct: 165 DRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGRE 224
Query: 801 RRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQ 860
+ ++R R + ++EE+EK+ K E K EE ++ EE Q++ E +EEEE+
Sbjct: 225 EKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQ-EEEPQRQREL--QEEEEQLRKL 281
Query: 861 LQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQS 920
+ R+ E+ + + + Q + + Q R E + +
Sbjct: 282 ERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRR 341
Query: 921 PPVPARKNQLRAEEEKKNVIMELSEMRKQLRSEERRLQERLLHMDSDDEIPIRKKERNPM 980
R+ QLR E+E++ +L +++ R E++ +E+ L + ++ ++ R
Sbjct: 342 EQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLR--REQQLRREQQLRREQ 399
Query: 981 DIFDMARHRLQAPVRRQSPKGLDAATFQNVHDFNELKDRDSETRVDLKFMYLDPPRDHHT 1040
+ + R + +RR+ Q + +L+ E R + K H
Sbjct: 400 QLRREQQLRREQQLRRE----------QQLRREQQLRREQEEERHEQK----------HE 439
Query: 1041 LEIQQQALLREQQKRLNRIKMQEGAKVDLDAIPSAKVREQRMPRDDTSD 1089
E ++Q L REQ++R + +K +E + + R+Q++ RD +
Sbjct: 440 QERREQRLKREQEERRDWLKREEETERH-----EQERRKQQLKRDQEEE 483
Score = 58.2 bits (139), Expect = 5e-08
Identities = 73/316 (23%), Positives = 133/316 (42%), Gaps = 41/316 (12%)
Query: 779 EEKKQREEAERERLRIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRL 838
EEK+ R + + L+ ++E++R E R R Q EE +++R+K +EQ + E
Sbjct: 97 EEKRARCDGKESLLQDRRQEEDQRRFEPRDR--QLEEEPGQRRRQKRQEQERELAEGEEQ 154
Query: 839 AEERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQR 898
+E++++ +R ++ +E+ Q Q + ER+ EE + LQ+ + +
Sbjct: 155 SEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQ-----------LQSCKGHETEE 203
Query: 899 PPSVDSIIRSFIHESSMSRAQSPPVPARKNQLRA--EEEKKNVIMELSEMRKQLRSEERR 956
P + + R + E + R+ Q R EEE+K E + LR EE +
Sbjct: 204 FPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEK----EWRKRETVLRKEEEK 259
Query: 957 LQERLLHMD---SDDEIPIRKKERNPMDIFDMARHRLQAPVRRQSPKGLDAATFQNVHDF 1013
LQE ++E +RK ER + + Q +RR+
Sbjct: 260 LQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQ--------------- 304
Query: 1014 NELKDRDSETRVDLKFMYLDPPRDHHTLEIQQQALLREQQKR----LNRIKMQEGAKVDL 1069
+ ++ E R + R E ++Q L REQ++R L R + +E + L
Sbjct: 305 QLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQL 364
Query: 1070 DAIPSAKVREQRMPRD 1085
+ REQ++ R+
Sbjct: 365 RREQEEERREQQLRRE 380
Score = 52.0 bits (123), Expect = 4e-06
Identities = 81/372 (21%), Positives = 158/372 (42%), Gaps = 63/372 (16%)
Query: 762 LQIKQQELYKNFLRFQIEEKKQREEA--ERERLRIAEEKE------------------ER 801
LQ ++QE ++ RF+ +++ EE R + R +E+E +
Sbjct: 110 LQDRRQE--EDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQ 167
Query: 802 RLAEQRARIQQEYEEEQEKKREKEEEQRLK--------NEEHIR---LAEERQKEAERKK 850
R E+ R +QE++E +E++ E+E+ Q K +EE +R L E R+K E K+
Sbjct: 168 RRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQ 227
Query: 851 KEEEEKYNLQLQ-----HYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSI 905
++ E+ + Q + +R+ ++ +E + +++ P + + + +
Sbjct: 228 QQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEP------QRQRELQEEEEQLRKL 281
Query: 906 IRSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLRSEERRLQERLLHMD 965
R + Q R+ QLR ++E E R++ + E R QER +
Sbjct: 282 ERQELRRERQEEEQQQQRLRREQQLRRKQE---------EERREQQEERREQQERREQQE 332
Query: 966 SDDEIPIRK--KERNPMDI-FDMARHRLQAPVRRQSPKGLDAATFQNVHDFNELKDRDSE 1022
E +R+ +ER + + R + +RR+ + Q + +L+ R+ +
Sbjct: 333 ERREQQLRREQEERREQQLRREQEEERREQQLRREQE---EERREQQLRREQQLR-REQQ 388
Query: 1023 TRVDLKFMYLDPPRDHHTLEIQQQALLREQQKRLNRIKMQEGAKVDLDAIPSAKVREQRM 1082
R + + R L +QQ L REQQ R + +E + + + REQR+
Sbjct: 389 LRREQQLRREQQLRREQQLRREQQ-LRREQQLRREQQLRREQEEERHEQKHEQERREQRL 447
Query: 1083 PR--DDTSDFLK 1092
R ++ D+LK
Sbjct: 448 KREQEERRDWLK 459
Score = 52.0 bits (123), Expect = 4e-06
Identities = 62/279 (22%), Positives = 116/279 (41%), Gaps = 23/279 (8%)
Query: 619 EDKPKPSKQSLQSYQEALQQQIREREERRKKEREEKEEYEAKLEAEMRTYNPWGKGGGGA 678
+++ + ++ Q QE +QQ+ +E RK EE + + E ++R
Sbjct: 1615 QERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQ 1674
Query: 679 PLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAEN-------L 731
L++ + L R R R E +R + + L E L
Sbjct: 1675 LLQEGEEQ---QLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQL 1731
Query: 732 EDAANKSSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNF-----LRFQIEEKKQREE 786
+ Q + E Q+++QE + F LR + EE++ R +
Sbjct: 1732 RQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQ 1791
Query: 787 AE----RERLRIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEER 842
RE ++ +E+EE++L Q+ + +EEEQ + E+E+ R + + R AEE+
Sbjct: 1792 ESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYR-AEEQ 1850
Query: 843 QKEAERKKKEEEEKYNLQLQ-HYCERDNLIGEETKHMRQ 880
E+ ++EE+E + + Q ER+ + EE H+R+
Sbjct: 1851 FATQEKSRREEQELWQEEEQKRRQERERKLREE--HIRR 1887
Score = 49.3 bits (116), Expect = 2e-05
Identities = 77/369 (20%), Positives = 153/369 (41%), Gaps = 41/369 (11%)
Query: 114 EDYERKKHKLK-----EELRQDYRRYLTQGITQGKRKKNFLSTSETDPSTLGVSLPIGER 168
E ER++ +LK E L+Q R Q +R++ L E E+
Sbjct: 510 EQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRL---------EQ 560
Query: 169 LSAKERLKLERNKEYNQFLRGKEESSEKFRQVEKSTEPKSQRNKKPIGQVKPDLTSQIQT 228
++RLK E+ + +Q L+ +EE ++ + E+ + + ++ + +++ + + +
Sbjct: 561 ERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRL 620
Query: 229 SCENSEGPRKDVLTPSEAYEELLNQ--RRLEEDRYRQL---DDEIELRNRRIIKKANEEV 283
E E R+ L SE EE Q RR +++R Q ++E E +R+ ++ EE
Sbjct: 621 KREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEER 680
Query: 284 GISNLKHQ-----RFASKAGIPDRRFHRFNE-DRVFDRRYHRPDQDP---EVSEEMDERF 334
L + R K+ IP ++ +E D + Y RP + E+ ++R
Sbjct: 681 REQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRR 740
Query: 335 RYESDF----DRRLSRVYTNDRMHRNKRGNMPPMEHDGDVIEQSNIRISSAENKSAPDNE 390
R ES+ + R R + R+ E ++ + R E +
Sbjct: 741 RRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRA 800
Query: 391 TSKSANQDTCSPFAGMLFGGEDRELIQRRKEKYRLEL-LEQMAEQQRNKRREKDLELRVA 449
+ + P E+ E QRR+++ E L+ + E+++ +RRE+ +L+
Sbjct: 801 EERQQREQRFLP--------EEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEE 852
Query: 450 ASGAQDPEK 458
G Q+ ++
Sbjct: 853 EDGLQEDQE 861
Score = 47.8 bits (112), Expect = 7e-05
Identities = 81/403 (20%), Positives = 165/403 (40%), Gaps = 49/403 (12%)
Query: 114 EDYERKKHKLKEELRQD-YRRYLTQGITQGKRKKNFLSTSETDPSTLGVSLPIGERLSAK 172
++ ERK + +++LRQ+ +R++ + +R++ L E D L +
Sbjct: 1442 QERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLE---------EEQ 1492
Query: 173 ERLKLERNKEYNQFLRGKEESSEKFRQVEKSTEPKSQRNKKPIGQVKPDLTSQIQTSCEN 232
+ + ER++++ + +E KF + E+ + QR +K + Q + L Q +
Sbjct: 1493 QLRRQERDRKFREQELRSQEPERKFLEEEQQLH-RQQRQRKFL-QEEQQLRRQERGQQRR 1550
Query: 233 SEGPRK----DVLTPSEAYEELLNQRR-----LEEDRYRQ-------LDDEIELRNRRII 276
+ RK + L ++L Q R LEE + R+ ++DE +LR +
Sbjct: 1551 QDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQ 1610
Query: 277 KKANEEVGISNLKHQRFASKAGIPDRRFHRFNEDRVF---DRRYHRPDQDPEVSEEMDER 333
++ +E + ++ + +++ HR DR F + + R +++ ++ + D +
Sbjct: 1611 QQLRQERDRKFREDEQLLQER--EEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRK 1668
Query: 334 FRYESDF----DRRLSRVYTNDRMHRNKRGNMPPMEHDGDVI-EQSNIRISSAENKSAPD 388
FR E + + R DR R + + E + + E+ +R E K +
Sbjct: 1669 FREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREE 1728
Query: 389 NETSKSANQDTCSPFAGMLFGGEDRELIQRRKE----------KYRLE-LLEQMAEQQRN 437
+ + Q+ E+ +L R+E K+R E L Q E+Q+
Sbjct: 1729 EQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQL 1788
Query: 438 KRREKDLELRVAASGAQDPEKSPDRLKQFSVAPRHFEEMIPPE 480
+ +E D + R Q+ E+ R +Q R EE + E
Sbjct: 1789 RSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLE 1831
Score = 46.6 bits (109), Expect = 1e-04
Identities = 85/437 (19%), Positives = 183/437 (41%), Gaps = 43/437 (9%)
Query: 46 EEQKARLAEDKAELESDPPYMEMKGKLSAKLSENSKILISMAKENIPPNSQQTRGSLGI- 104
EE+K + + E E + ++E + +L + E ++ L +E+ Q+ R S
Sbjct: 814 EEEKEQRRRQRREREKELQFLEEEEQLQRR--ERAQQL--QEEEDGLQEDQERRRSQEQR 869
Query: 105 -DYGLSLPLGEDYERKKHKL------KEELRQDYR--RYLTQGITQGKRKKNFLSTSETD 155
D L E+ +R++H L +E+LR++ + + + + + +R+K E
Sbjct: 870 RDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQ 929
Query: 156 PSTLGVSLPIGERLSAKERLKLERNKEYNQFLRGKE----------ESSEKFRQVEKSTE 205
E+L +ER K R + Q+ + K+ E EK R+ E+
Sbjct: 930 YREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQERE-- 987
Query: 206 PKSQRNKKPIGQVKPDLTSQIQTSCENSEGPR----KDVLTPSEAYEELLNQRRLEEDRY 261
K R ++ + Q + L + + E R KD L E E+LL + R ++
Sbjct: 988 -KKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEE--EQLLREER---EKR 1041
Query: 262 RQLDDEIELRNRRIIKKANEEVGISNLKHQRFASKAGIPDRRFHRFNEDRVFDRRYHRPD 321
R + E + R +++ E++ L +R + +R++ + E + + + R +
Sbjct: 1042 RLQERERQYREEEELQQEEEQL----LGEERETRRRQELERQYRKEEELQQEEEQLLREE 1097
Query: 322 QDPEVSEEMDERFRYESDFDRRLSRVYTNDRMHRNKRGNMPPMEHDGDVIEQSNIRISSA 381
+ +E + + R E + + ++ +R R +R + + + ++Q ++
Sbjct: 1098 PEKRRRQERERQCREEEELQQEEEQLLREEREKR-RRQELERQYREEEEVQQEEEQLLRE 1156
Query: 382 ENKSAPDNETSKSANQDTCSPFAGMLFGGEDRELIQRRKEKYRLELLEQMAEQQRNKRRE 441
E + E + ++ E++E +RR+E+ R E+ ++Q+ K+R
Sbjct: 1157 EPEKRRRQELERQYREEEELQQEEEQLLREEQE--KRRQERERQYREEEELQRQKRKQRY 1214
Query: 442 KDLELRVAASGAQDPEK 458
+D + R +PEK
Sbjct: 1215 RDEDQRSDLKWQWEPEK 1231
Score = 45.8 bits (107), Expect = 3e-04
Identities = 53/244 (21%), Positives = 105/244 (43%), Gaps = 47/244 (19%)
Query: 231 ENSEGPRKDVLTPSEAYEELLNQRRLEEDRYRQLD-------------DEIELRNRRIIK 277
E E R+D S+ ++LL + R E+ R ++ D +E LR + +
Sbjct: 1303 EQKEAKRRD--RKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDR 1360
Query: 278 KANEEVGISNLKHQRFASKAGIPDRRFHRFNEDRVF---DRRYHRPDQDPEVSEEMDERF 334
K EE L+HQ K ++R R +R F +++ +++ ++ ++ D +F
Sbjct: 1361 KFREE----ELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKF 1416
Query: 335 RYESDFDRRLSRVYTNDRMHRNKRGNMPPMEHDGDVIEQSNIRISSAENKSAPDNETSKS 394
R E +++LSR DR R E+ +R E K + + +
Sbjct: 1417 REE---EQQLSR-QERDRKFRE---------------EEQQVRRQERERKFLEEEQQLRQ 1457
Query: 395 ANQDTCSPFAGMLFGGEDRELIQRRKEKYRLELLEQMAEQQRNKRREKDLELRVAASGAQ 454
+L E+++L ++ +++ LE E+Q+ +R+E+D + R +Q
Sbjct: 1458 ERHRKFREEEQLLQEREEQQLHRQERDRKFLE------EEQQLRRQERDRKFREQELRSQ 1511
Query: 455 DPEK 458
+PE+
Sbjct: 1512 EPER 1515
Score = 43.9 bits (102), Expect = 0.001
Identities = 82/385 (21%), Positives = 153/385 (39%), Gaps = 55/385 (14%)
Query: 114 EDYERKKHKLK-EELRQDYRRYLTQGITQGKRKKNFLSTSETDPSTLGVSLPIGERLSAK 172
E ER++ +LK EE ++ R+ L + Q +R++ L + + + +R +
Sbjct: 611 EQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRL-----KREEEE 665
Query: 173 ERLKLERNKEYNQFLRGKE---ESSEKFRQVEKSTEPKSQRNKKPIGQVKPDLTSQIQTS 229
ERL+ +E+ + R +E E E+ R+ KS PK Q + + S++ +
Sbjct: 666 ERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQ---SKVYSR 722
Query: 230 CENSEGPRKDVLTPSEAYEELLNQRRLEEDR-YRQLDDEIELRNRRIIKKANEEVGISNL 288
EG R+ + + EE+R +RQ +E + R+ +A E+ S
Sbjct: 723 PRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEK---SER 779
Query: 289 KHQRFASKAGIPDRRFHRFNEDRVFDRRYHRPDQDPEVSEEMDERFRYESDFDRRLSRVY 348
QR +++ P R R + R +R+ PE EE ++R R + ++ L +
Sbjct: 780 GRQRLSAR---PPLREQRERQLRAEERQQREQRFLPE-EEEKEQRRRQRREREKELQFLE 835
Query: 349 TNDRMHRNKRGNMPPMEHDGDVIEQSNIRISSA------------ENKSAPDNETSKSAN 396
+++ R +R E DG +Q R E K +K A
Sbjct: 836 EEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPAL 895
Query: 397 QDTCSPFAGMLFGGEDR---------------------ELIQRRKEKYRLELLEQMAEQQ 435
Q+ +L E+ E +Q+ +E+ E E+ Q+
Sbjct: 896 QEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQE 955
Query: 436 RNK--RREKDLELRVAASGAQDPEK 458
R + R++K L+ + ++PEK
Sbjct: 956 RERQYRKDKKLQQKEEQLLGEEPEK 980
Score = 41.6 bits (96), Expect = 0.005
Identities = 69/370 (18%), Positives = 149/370 (40%), Gaps = 63/370 (17%)
Query: 117 ERKKHKLKEELRQDYRRYLTQGITQGKRKKNFLSTSETDPSTLGVSLPIGERLSAKERLK 176
ER++ +L + R R Q + + ++++ F+ D L R +++L+
Sbjct: 1566 EREEQQLSRQERDRKFRLEEQKVRRQEQERKFME----DEQQL-------RRQEGQQQLR 1614
Query: 177 LERNKEYN---QFLRGKEESSEKFRQVEKS---TEPKSQRNKKPIGQVKPDLTSQIQTSC 230
ER++++ Q L+ +EE ++ ++ EP+ +R ++ Q++ D + +
Sbjct: 1615 QERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQERE-QQLRHDRDRKFREEE 1673
Query: 231 ENSEGPRKDVLTPSEA---YEELLNQRRLEEDRYRQLDDEIELRNRRIIKKANEEVGISN 287
+ + + L E + E Q R +E + L +E +LR + + +K EE +
Sbjct: 1674 QLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQ 1733
Query: 288 LKHQRFASKAGIPDRRFHRFNEDRVFDRRYHRPDQDPEV--SEEMDERFRYESDF----D 341
Q RR R+ ++ + RP+++ + +E D +FR E +
Sbjct: 1734 ETEQEQL-------RRQERYR--KILEEEQLRPEREEQQLRRQERDRKFREEEQLRQERE 1784
Query: 342 RRLSRVYTNDRMHRNKRG--------NMPPMEHDGDVI-EQSNIRISSAENKSAPDNETS 392
+ R +DR R + + P + DG E+ +++ E + + +
Sbjct: 1785 EQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQ 1844
Query: 393 KSANQDTCSPFAGMLFGGEDRELIQRRKEKYRLELLEQMAEQQRNKRREKDLELRVAASG 452
A + + +EK R E E E+++ +R+E++ +LR
Sbjct: 1845 YRAEEQFAT------------------QEKSRREEQELWQEEEQKRRQERERKLREEHIR 1886
Query: 453 AQDPEKSPDR 462
Q E+ R
Sbjct: 1887 RQQKEEQRHR 1896
Score = 41.2 bits (95), Expect = 0.006
Identities = 57/304 (18%), Positives = 122/304 (40%), Gaps = 52/304 (17%)
Query: 46 EEQKARLAEDKAELESDPPYMEMKGKLSAKLSENSKILISMAKENIPPNSQQTRGSLGID 105
+EQ+ + ED+ +L +++ + K E+ ++L ++ + +Q R ++
Sbjct: 1591 QEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQL---HRQERDRKFLE 1647
Query: 106 YGLSLPLGEDYERKKHKLKEELRQDYRRYLTQGITQGKRKKNFLSTSETDPSTLGVSLPI 165
L E ++ +H + R++ + L +G Q R++
Sbjct: 1648 EEPQLRRQEREQQLRHDRDRKFREE-EQLLQEGEEQQLRRQE------------------ 1688
Query: 166 GERLSAKERLKLERNKEYNQFLR-----GKEESSEKFRQVEKSTEPKSQRNKKPIGQVKP 220
+R +E +L R + +FL+ ++E KFR+ E+ + Q + + +
Sbjct: 1689 RDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRK 1748
Query: 221 DLTSQIQTSCENSEGPRKDVLTPSEAYEELLNQRR----LEEDRYRQLDDEIELRNRRII 276
L ++ L P ++L Q R EE++ RQ +E +LR++
Sbjct: 1749 IL--------------EEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESD 1794
Query: 277 KKANEEVGISNLKHQRFASKAGIPDRRFHRFNEDRVFDRRYHRPDQDPEVSEEMDERFRY 336
+K EE L+ +R + R R + R + + +Q+ + +E D ++R
Sbjct: 1795 RKFREE---EQLRQEREEQQL----RPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRA 1847
Query: 337 ESDF 340
E F
Sbjct: 1848 EEQF 1851
Score = 41.2 bits (95), Expect = 0.006
Identities = 48/216 (22%), Positives = 94/216 (43%), Gaps = 26/216 (12%)
Query: 637 QQQIREREERRKKEREEKEEYEAKLEAEMRTYNPWGKGGGGAPLRDAKGNLITDLNRMHR 696
+QQ+R +E RK EE+ E + E ++R + K LR + + ++ R
Sbjct: 1713 EQQLRRQELERKFREEEQLRQETEQE-QLRRQERYRKILEEEQLRPER-----EEQQLRR 1766
Query: 697 QNIDAYHNPDARTYEDKRAVVSLDPNLATSNAEN-LEDAANKSSGHMQTQSSPFARGNVF 755
Q D + + +++ + L + ++ + + Q P R +
Sbjct: 1767 QERDRKFREEEQLRQERE-----EQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKY 1821
Query: 756 GEPPTELQIKQQEL---------YKNFLRFQIEEKKQREEAE--RERLRIAEEKEERRLA 804
+LQ+++QE Y+ +F +EK +REE E +E + ++ ER+L
Sbjct: 1822 RWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLR 1881
Query: 805 EQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAE 840
E+ R QQ +E+++ R+ E + + + H RL E
Sbjct: 1882 EEHIRRQQ---KEEQRHRQVGEIKSQEGKGHGRLLE 1914
Score = 39.3 bits (90), Expect = 0.024
Identities = 73/387 (18%), Positives = 148/387 (38%), Gaps = 37/387 (9%)
Query: 114 EDYERKKHKLKEELRQDYRRYLTQGITQGKRKKNFLSTSETDPSTLGVSLPIGERLSAKE 173
E ER++ +L+ E ++ R + + +R++ L + L ++L ++
Sbjct: 342 EQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQ--------QLRREQQLRREQ 393
Query: 174 RLKLERNKEYNQFLRGKEESSEKFRQVEKSTEPKSQRNKKPIGQVKPDLTSQIQTSCENS 233
+L+ E+ Q LR +E+ + +Q+ + + + ++ ++ Q + + E
Sbjct: 394 QLRREQQLRREQQLR-REQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQE 452
Query: 234 EGPRKDVLTPSEAYEELLNQRRLEEDRYRQLDDEIELRNRRIIKKANEEVGISNLKHQRF 293
E R+D L E E R +E R +QL + E R K EE + +
Sbjct: 453 E--RRDWLKREEETE-----RHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQ 505
Query: 294 ASKAGIPDRRFHRFNEDRVFDRRYHRPDQDPEVSEEMDERFRY--ESDFDRRLSRVYTND 351
+ +RR R +R R + ++ E +ER + + ++RL +
Sbjct: 506 QLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQ 565
Query: 352 RMHRNKRGNMPPMEHDGDVIEQSNIRISSAEN--KSAPDNETSKSANQDTCSPFAGMLFG 409
R+ R + + + Q ++ E + E + ++
Sbjct: 566 RLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEER---------- 615
Query: 410 GEDRELIQRRKEKYRLELL---EQMAEQQRNKRREKDLELRVAASGAQDPEKSPDRLKQF 466
E R + +E+ R +LL EQ +Q+ RRE+ ++ E+ RLK+
Sbjct: 616 REQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKRE 675
Query: 467 SVAPRHFEEMIPPE----RPRIAFQTP 489
R +E+ E R RI + P
Sbjct: 676 HEEERREQELAEEEQEQARERIKSRIP 702
Score = 38.9 bits (89), Expect = 0.031
Identities = 55/313 (17%), Positives = 134/313 (42%), Gaps = 22/313 (7%)
Query: 167 ERLSAKERLKLERNKEYNQFLRGKEESSEKFRQVEKSTEPKSQRNKKPIGQVKPDLTSQI 226
ER +ER + + + Q R +EE E+ + E+ E + Q+ ++ + + + +
Sbjct: 320 ERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRR 379
Query: 227 QTSCENSEGPRKDVLTPSEAYEELLNQRRLEEDRYRQLDDEIELRNRRIIKKANEEVGIS 286
+ + R++ E ++L +++L R +QL E +LR + +++ EE
Sbjct: 380 EQQLRREQQLRREQQLRRE--QQLRREQQLR--REQQLRREQQLRREQQLRREQEEER-H 434
Query: 287 NLKHQRFASKAGIPDRRFHRFNEDRVFDRRYHRPDQDPEVSEEMDERFRYESDFD----R 342
KH++ +RR R ++ R + + +++ E E+ + + + D +
Sbjct: 435 EQKHEQ--------ERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRE 486
Query: 343 RLSRVYTNDRMHRNKRGNMPPMEHDGDVIEQSNIRISSAENKSAPDNETSKSANQDTCSP 402
R ++ +R + +R + + + + ++ E + + + ++
Sbjct: 487 RWLKLEEEERREQQERREQ-QLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEER 545
Query: 403 FAGMLFGGEDRELIQRRKEKYRLELLEQMAEQQRNKRREKDLELRVAASGAQDPEKSPDR 462
+L E++ L Q R+E + L++ E++R++ +++ E R + E+ R
Sbjct: 546 REQLLKREEEKRLEQERRE----QRLKREQEERRDQLLKREEERRQQRLKREQEERLEQR 601
Query: 463 LKQFSVAPRHFEE 475
LK+ V EE
Sbjct: 602 LKREEVERLEQEE 614
Score = 37.4 bits (85), Expect = 0.091
Identities = 57/287 (19%), Positives = 107/287 (37%), Gaps = 59/287 (20%)
Query: 173 ERLKLERNKEYNQFLRGKEESSEKFRQVEKSTEPKS-----QRNKKPIGQVKPDLTSQIQ 227
+R + +R ++ + G+E+S ++ R ++ + + QR + + + Q+Q
Sbjct: 135 QRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQ 194
Query: 228 TSC---ENSEGPRKDVLTPSEAYE-------ELLNQRRLEEDRYRQLDDEIELRNRRIIK 277
SC E E P ++ L E E E QRR +DR Q ++E E R R +
Sbjct: 195 -SCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVL 253
Query: 278 KANEEVGISNLKHQRFASKAGIPDRRFHRFNEDRVFDRRYHRPDQDPEVSEEMDERFRYE 337
+ EE + E+ P + E+ EE +E+ R
Sbjct: 254 RKEEE-----------------------KLQEE--------EPQRQRELQEE-EEQLRKL 281
Query: 338 SDFDRRLSRVYTNDRMHRNKRGNMPPMEHDGDVIEQSNIRISSAENKSAPDNETSKSANQ 397
+ R R + R +R + + + EQ R E + + + +
Sbjct: 282 ERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRR 341
Query: 398 DTCSPFAGMLFGGEDRELIQRRKEKYRLELLEQMAEQQRNKRREKDL 444
+ E+R Q R+E+ +Q+ +Q +RRE+ L
Sbjct: 342 EQ-----------EERREQQLRREQEEERREQQLRREQEEERREQQL 377
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 83.6 bits (205), Expect = 1e-15
Identities = 76/360 (21%), Positives = 162/360 (45%), Gaps = 16/360 (4%)
Query: 619 EDKPKPSKQSLQSYQEALQQQ---IREREERRKKEREEKEEYEAKLEA-EMRTYNPWGKG 674
E+K + ++ +Q +E +++Q IRE+EE+ +++ E E E K+ E + K
Sbjct: 367 EEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM 426
Query: 675 GGGAPLRDAKGNLITDLN-RMH-----RQNIDAYHNPDARTYEDKRAVVSLDPNLATSNA 728
+ K I +L +MH R+ + + ++KR
Sbjct: 427 RRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKI 486
Query: 729 ENLEDAANKSSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEK--KQREE 786
E+ + M Q E E + +Q+E+++ + + +E+ +Q+E+
Sbjct: 487 REQEEKIREQEEKMWRQEEKIHEQEKIREE--EKRQEQEEMWRQEEKIREQEEIWRQKEK 544
Query: 787 AERERLRIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEA 846
+ +I +++E+ E++ Q+E EQE+K ++EE+ + EE IR EE+ +E
Sbjct: 545 IHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQ 604
Query: 847 ERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSII 906
E +E+EEK Q + CE++ + E+ + MR+ + + KI + ++ + ++
Sbjct: 605 EEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMM 664
Query: 907 RSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLRSEERRLQERLLHMDS 966
+ E M + + EE+ + ++ E +LR +E ++QE H+++
Sbjct: 665 QE--QEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEA 722
Score = 66.2 bits (160), Expect = 2e-10
Identities = 78/329 (23%), Positives = 145/329 (44%), Gaps = 48/329 (14%)
Query: 761 ELQIKQQELYKNFLRFQIEEKKQREEA---------ERERLRIAEEKEERRLAEQRARIQ 811
+ Q+++ EL+ N L Q EEK R+E + + +I E++E+ R E++ R Q
Sbjct: 343 QAQVEENELW-NRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQ 401
Query: 812 QEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCERDNLI 871
+E E+E+K ++EE + EE +R EE E E K +E EEK + E++ +
Sbjct: 402 EEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMH-------EQEKIR 454
Query: 872 GEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPARKNQLR 931
+E K + KI + +R + R + R Q + ++ ++
Sbjct: 455 EQEEKRQE---------EEKIREQEKRQEQEAKMWR----QEEKIREQEEKIREQEEKMW 501
Query: 932 AEEEKKNVIMELSEMRKQLRSEERRLQERLLHMDSDDEIPIRKKERNPMDIFDMARHRLQ 991
+EEK + ++ E K+ EE QE + + E R+KE+ H +
Sbjct: 502 RQEEKIHEQEKIREEEKRQEQEEMWRQEEKIR---EQEEIWRQKEK---------IHEQE 549
Query: 992 APVRRQSPKGLDAATFQNVHDFNELKDRDSETRVDLKFMYLDPPRDHHTLEIQQQALLRE 1051
+R+Q K + +HD E K R+ E +V + + R+ +Q+ +RE
Sbjct: 550 EKIRKQEEKMWRQE--EKMHD-QEEKIREQEEKV---WRQEEKIREQEEKIREQEEKIRE 603
Query: 1052 QQKRLNRIKMQEGAKVDLDAIPSAKVREQ 1080
Q++ + + G + + K++EQ
Sbjct: 604 QEEMTQEQEEKMGEQEEKMCEQEEKMQEQ 632
Score = 55.1 bits (131), Expect = 4e-07
Identities = 48/241 (19%), Positives = 109/241 (45%), Gaps = 27/241 (11%)
Query: 619 EDKPKPSKQSLQSYQEALQQQIREREERRKKEREEKEEYEAKLEAEMRTYNPWGKGGGGA 678
E+K + ++ + +E + +Q + REE +++E+EE E K+ + + K
Sbjct: 490 EEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEK----- 544
Query: 679 PLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAANKS 738
+ + + + +M RQ + H+ + + E + V + + + E
Sbjct: 545 -IHEQEEKIRKQEEKMWRQE-EKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIR 602
Query: 739 SGHMQTQSSPFARGNV---FGEPPTELQIKQQELYKNFLRFQIEEKKQREEAE--RERLR 793
TQ G E ++Q +++++ + + + +EKK RE+ E RE+
Sbjct: 603 EQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEE 662
Query: 794 IAEEKEER------RLAEQRARIQQEYEE---------EQEKKREKEEEQRLKNEEHIRL 838
+ +E+EE+ ++ EQ ++Q++ E+ EQE + ++EE+ +++EH+
Sbjct: 663 MMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEA 722
Query: 839 A 839
A
Sbjct: 723 A 723
Score = 47.4 bits (111), Expect = 9e-05
Identities = 81/451 (17%), Positives = 187/451 (41%), Gaps = 64/451 (14%)
Query: 42 DEFIEEQKARLAEDKAELESDPPYMEMKGKLSAKLSENSKILISMAKENIPPNSQQTRGS 101
DE ++E+ A+L E +ES+ +++ K + E +K+L +P Q
Sbjct: 277 DEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLL-------LPQQQLQAEAD 329
Query: 102 LGIDYGLSLPLGEDYERKKHKLKEELRQDYRRYLTQGITQGKRKKNFLSTSETDPSTLGV 161
LG++ + KL+ ++ ++ L + Q + +K + +
Sbjct: 330 ---------HLGKELQSVSAKLQAQVEEN---ELWNRLNQQQEEKMWRQEEKIQEWE--- 374
Query: 162 SLPIGERLSAKERLKLERNKEYNQFLRGKEESSEKFRQVEKSTEPKSQRNKKPIGQVKPD 221
E++ +E E+ +E + +R +EE + ++ E K +R ++ + + +
Sbjct: 375 -----EKIQEQE----EKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 425
Query: 222 LTSQIQTSCENSEGPRKDVLTPSEAYEELLNQRRL-EEDRYRQLDDEIELRNRRIIKKAN 280
+ Q + E E R E E++ Q ++ E++ RQ +++I + +R ++A
Sbjct: 426 MRRQEEMMWEKEEKIR-------ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK 478
Query: 281 EEVGISNLKHQRFASKAGIPDRRFHRFNEDRVFDRRYHRPDQDPEVSEEM---DERFRYE 337
++ Q K + + R E+++ ++ R ++ + EEM +E+ R +
Sbjct: 479 MWRQEEKIREQE--EKIREQEEKMWR-QEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQ 535
Query: 338 SDFDRRLSRVYTNDRMHRNKRGNM----PPMEHDGDVIEQSNIRISSAENKSAPDNETSK 393
+ R+ +++ + R + M M + I + ++ E K E +
Sbjct: 536 EEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIR 595
Query: 394 SANQDTCSPFAGMLFGGEDRELIQRRKEKYRLELLEQMAEQQRNKRREKDLELRVAASGA 453
+ E E+ Q ++EK E E+M EQ+ K +E++ ++R
Sbjct: 596 EQEEKI----------REQEEMTQEQEEKMG-EQEEKMCEQE-EKMQEQEEKMRRQEEKI 643
Query: 454 QDPEKSPDRLKQFSVAPRHFEEMIPPERPRI 484
++ EK ++++ R EEM+ + ++
Sbjct: 644 REQEK---KIREQEEKIREQEEMMQEQEEKM 671
Score = 41.6 bits (96), Expect = 0.005
Identities = 64/363 (17%), Positives = 141/363 (38%), Gaps = 17/363 (4%)
Query: 114 EDYERKKHKLKEELRQDYRRYLTQGITQGKRKKNFLSTSETDPSTLGVSLPIGERLSAKE 173
+++E K + +E++R+ + Q ++++ E + E++ +E
Sbjct: 371 QEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQE 430
Query: 174 RLKLERNKEYNQFLRGKEESSEKFR-QVEKSTEPKSQRNKKPIGQVKPDLTSQIQTSCEN 232
+ E+ ++ + L K EK R Q EK E + R ++ + + + Q + E
Sbjct: 431 EMMWEKEEKIRE-LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ 489
Query: 233 SEGPRKDVLTPSEAYEELLNQRRLEEDRYRQLDDEIELRNRRIIKKANEEVGISNLKHQR 292
E R+ E++ Q ++ E+ RQ +E+ + +I + EE+ K
Sbjct: 490 EEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKI--REQEEIWRQKEKIHE 547
Query: 293 FASKAGIPDRRFHRFNEDRVFDRRYHRPDQDPEVSEEMDERFRYESDFDRRLSRVYTNDR 352
K + + R E+++ D+ +Q+ +V + ++ E + ++ +
Sbjct: 548 QEEKIRKQEEKMWR-QEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEE 606
Query: 353 MHRNKRGNMPPMEHDGDVIEQSNIRISSAENKSAPDNETSKSANQDTCSPFAGMLFGGED 412
M + + M E + + EQ ++ E K E + + + E
Sbjct: 607 MTQEQEEKMG--EQEEKMCEQEE-KMQEQEEKMRRQEEKIREQEKKIREQEEKIR---EQ 660
Query: 413 RELIQRRKEKY------RLELLEQMAEQQRNKRREKDLELRVAASGAQDPEKSPDRLKQF 466
E++Q ++EK E E+M EQ+ RR+++ Q EK + +
Sbjct: 661 EEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHL 720
Query: 467 SVA 469
A
Sbjct: 721 EAA 723
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 81.3 bits (199), Expect = 5e-15
Identities = 82/366 (22%), Positives = 168/366 (45%), Gaps = 32/366 (8%)
Query: 626 KQSLQSYQEALQQQIREREERRKKEREEK-EEYEAKLEAEMRTYNPWGKGGGGAPLRDAK 684
++ ++ +E + +Q + RE+ K++ EEK E E + E E + + K +R+ +
Sbjct: 390 EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEK------IREQE 443
Query: 685 GNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAANKSSGHMQT 744
+ +M RQ + H + E+KR E E K H Q
Sbjct: 444 EKIREQEKKMWRQE-EKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQE 502
Query: 745 QSSPFARGNVFGEPPT----ELQIKQQE--LYKNFLRFQIEEKKQREEAE-RERLRIAEE 797
+ V+ + E +I++QE +++ + + +E+ REE + E+ +I EE
Sbjct: 503 EKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEE 562
Query: 798 -----------KEERRLAEQRARI--QQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQK 844
++E ++ EQ ++ Q+E EQE+KR+++EE+ K EE IR EE+ +
Sbjct: 563 EKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQ 622
Query: 845 EAERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDS 904
E E K +E+EEK Q + E++ +GE+ + M + +Q + + ++ +
Sbjct: 623 EQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQE---EKMQEQEETMWRQEEKIRE 679
Query: 905 IIRSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIME-LSEMRKQLRSEERRLQERLLH 963
+ + R Q + ++ ++ +EEK E + E +++R +E ++ E+ +
Sbjct: 680 QEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVR 739
Query: 964 MDSDDE 969
+ +E
Sbjct: 740 LRQQEE 745
Score = 75.9 bits (185), Expect = 2e-13
Identities = 68/343 (19%), Positives = 150/343 (43%), Gaps = 38/343 (11%)
Query: 619 EDKPKPSKQSLQSYQEALQQQIREREERRKKEREEKEEYEAKLEAEMRTYNPWGKGGGGA 678
E+K + ++ + +E + +Q + REE +++E+EE E K+ + +
Sbjct: 443 EEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWR--------- 493
Query: 679 PLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAE--NLEDAAN 736
+MH Q + + + + + + + + + E+
Sbjct: 494 -----------QKEKMHEQE-EKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIR 541
Query: 737 KSSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAE 796
+ + + + ++ E K+QE R + + ++Q E+ R+ +I E
Sbjct: 542 EQEEMWREEEKMHEQEKIWEEE------KRQEQEDKMWRQEEKIREQEEKVWRQEEKIRE 595
Query: 797 EKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEK 856
++E+R+ E++ Q+E EQE+K +++EE+ + EE IR EE +E E K E+EEK
Sbjct: 596 QEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEK 655
Query: 857 YNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMS 916
Q + E++ + + + +R+ + + KI + + + + + E M
Sbjct: 656 MCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEE--KMWEQEEKMC 713
Query: 917 RAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLRSEERRLQE 959
Q + ++ ++R +EEK + E +LR +E ++QE
Sbjct: 714 E-QEEKMQEQEEKMRRQEEK------MWEQEVRLRQQEEKMQE 749
Score = 69.3 bits (168), Expect = 2e-11
Identities = 79/337 (23%), Positives = 150/337 (44%), Gaps = 21/337 (6%)
Query: 761 ELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERRLAEQRARIQQEYEEEQEK 820
+ Q+++ EL+ N L Q EEK R+E E+++ EEK + + E++ R Q+E EQE+
Sbjct: 282 QAQVEENELW-NRLNQQQEEKMWRQE---EKIQEWEEKIQEQ--EEKIREQEEKIREQEE 335
Query: 821 KREKEEEQRLKNEEHIRLAEERQKEAERKKK-------EEEEKYNLQLQHYCERDNLIGE 873
K ++EE + EE +R EE E E K + E+EEK Q + E++ I E
Sbjct: 336 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRE 395
Query: 874 ETKHMRQPSPIVPALQNK-IASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPARKNQLRA 932
+ M + I + + K++ + R Q + ++ ++
Sbjct: 396 LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWR 455
Query: 933 EEEKKNVIMELSEMRKQLRSEERRLQERLLHMDSDDEIPIRKKERNPMDIFDMARHRLQA 992
+EEK + ++ E K+ EE QE +H + E R+KE+ M + + +
Sbjct: 456 QEEKIHEQEKIREEEKRQEQEEMWRQEEKIH---EQEEIWRQKEK--MHEQEEKIRKQEE 510
Query: 993 PVRRQSPKGLDAATFQNVHDFNELKDRDSETRVDLKFMYLDPPRDHHTLEIQQQALLREQ 1052
V RQ K + + + + E R E + + M+ + + H +I ++ +EQ
Sbjct: 511 KVWRQEEKIREQE--EKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQ 568
Query: 1053 QKRLNRIKMQEGAKVDLDAIPSAKVREQRMPRDDTSD 1089
+ ++ R + + + + K+REQ R + +
Sbjct: 569 EDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEE 605
Score = 60.5 bits (145), Expect = 1e-08
Identities = 77/380 (20%), Positives = 160/380 (42%), Gaps = 51/380 (13%)
Query: 597 NTVGQNELKITSDQVINSGLIFEDKPKPSKQSLQSYQEAL--------QQQIREREERRK 648
NT+ ELK + ++ + E + + +++ + L QQQ++ +
Sbjct: 212 NTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLG 271
Query: 649 KEREEKEEYEAKLEAEMRTYNPWGKGGGGAPLRDAKGNLITDLNRMHRQNIDAYHNPDAR 708
KE + AKL+A++ W NR+++Q + + +
Sbjct: 272 KELQS---VSAKLQAQVEENELW--------------------NRLNQQQEEKMWRQEEK 308
Query: 709 TYEDKRAVVSLDPNLATSNAE--NLEDAANKSSGHMQTQSSPFARGNVFGEPPTELQIKQ 766
E + + + + + E+ + M + R E +Q
Sbjct: 309 IQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQ 368
Query: 767 QELYKNFLRFQIEEKKQREEA----ERERLRIAEEK--EERRLAEQRARIQQEYEEEQEK 820
+E+ ++ EEK +R+E + E++R EEK E+ ++ EQ + Q+E + +++
Sbjct: 369 EEMM-----WEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE 423
Query: 821 KREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQ 880
KR+++E + + EE IR EE+ +E E+K +EEK + Q + E+ + RQ
Sbjct: 424 KRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEK--IHEQEKIREEEKRQEQEEMWRQ 481
Query: 881 PSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVI 940
I Q +I + ++ + IR E + R Q + ++ ++R +EEK
Sbjct: 482 EEKIHE--QEEIWRQKEKMHEQEEKIRK--QEEKVWR-QEEKIREQEEKIREQEEKMWRQ 536
Query: 941 MELSEMRKQLRSEERRLQER 960
E ++++ EE ++ E+
Sbjct: 537 EEKIREQEEMWREEEKMHEQ 556
Score = 38.5 bits (88), Expect = 0.041
Identities = 78/454 (17%), Positives = 175/454 (38%), Gaps = 59/454 (12%)
Query: 42 DEFIEEQKARLAEDKAELESDPPYMEMKGKLSAKLSENSKILISMAK-----ENIPPNSQ 96
DE ++E+ A+L E +ES+ +++ K + E +K+L+ + +++ Q
Sbjct: 216 DEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQ 275
Query: 97 QTRGSLGIDYGLSLPLG-----------------EDYERKKHKLKEELRQDYRRYLTQGI 139
L + +++E K + +E++R+ + Q
Sbjct: 276 SVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEE 335
Query: 140 TQGKRKKNFLSTSETDPSTLGVSLPIGERLSAKERL---KLERNKEYNQFLRGKEE---- 192
++++ E + E++ +E + K E+ + + + KEE
Sbjct: 336 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRE 395
Query: 193 ------SSEKFR-QVEKSTEPKSQRNKKPIGQVKPDLTSQIQTSCENSEGPRKDVLTPSE 245
EK R Q EK E + R ++ + + + Q + E E R+
Sbjct: 396 LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWR 455
Query: 246 AYEELLNQRRLEEDRYRQLDDEIELRNRRIIKKANEEVGISNLKHQRFASKAGIPDRRFH 305
E++ Q ++ E+ RQ +E+ + +I +E+ I K + + I
Sbjct: 456 QEEKIHEQEKIREEEKRQEQEEMWRQEEKI----HEQEEIWRQKEKMHEQEEKI------ 505
Query: 306 RFNEDRVFDRRYHRPDQDPEVSEEMDERFRYESDFDRRLSRVYTNDRMH-RNKRGNMPPM 364
R E++V+ + +Q+ ++ E+ ++ +R E + ++MH + K
Sbjct: 506 RKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKR 565
Query: 365 EHDGDVIEQSNIRISSAENKSAPDNETSKSANQDTCSPFAGMLFGGEDRELIQRRKEKYR 424
+ D + + +I E K E + + E E + +++EK R
Sbjct: 566 QEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKR----------QEQEEKMWKQEEKIR 615
Query: 425 LELLEQMAEQQRNKRREKDLELRVAASGAQDPEK 458
+ E+ ++Q K RE++ ++R Q+ E+
Sbjct: 616 EQ--EEKIQEQEEKIREQEEKIREQEEMTQEQEE 647
Score = 32.3 bits (72), Expect = 2.9
Identities = 33/173 (19%), Positives = 79/173 (45%), Gaps = 22/173 (12%)
Query: 818 QEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEETKH 877
Q+KK ++ E+ K + + L R + + KE+ K +LQ + I K
Sbjct: 187 QKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKE 246
Query: 878 MRQ---------PSPIVPALQNKIASKLQRPPSVDSIIRSFIHESS----MSRAQSPPVP 924
+++ P + A + + +LQ SV + +++ + E+ +++ Q +
Sbjct: 247 LKRKLERAKLLLPQQQLQAEADHLGKELQ---SVSAKLQAQVEENELWNRLNQQQEEKMW 303
Query: 925 ARKNQLRAEEEKKNVIMELSEMRKQLRSEERRLQERLLHMDSDDEIPIRKKER 977
++ +++ EEK + E +++R +E +++E+ M +E+ K+E+
Sbjct: 304 RQEEKIQEWEEK------IQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEK 350
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 78.2 bits (191), Expect = 5e-14
Identities = 121/539 (22%), Positives = 225/539 (41%), Gaps = 97/539 (17%)
Query: 619 EDKPKPSKQSLQSYQEALQQQIREREERRKKEREE--KEEYEAK-LEAEMRTY--NPWGK 673
E P + SL +Q E E K+E+ E +E YE + E ++Y N W
Sbjct: 120 EFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDW-- 177
Query: 674 GGGGAPLRDAKGNLITDLNRMHRQN------------IDAYHNPDARTYEDKRAVVSLDP 721
RDA+ N D + + ++ +++ V+SL
Sbjct: 178 -------RDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKN 230
Query: 722 NLATSNA----ENLEDAANKSSGHMQTQS-----SPFARGNVFGEPPTELQIKQ-QELYK 771
+S E E +++ S H + + + R + E ++ +Q +++
Sbjct: 231 GQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIAD 290
Query: 772 NFLRFQIEEK------KQREEAERERLRIAEEKEERRLAEQRARIQQEYEE--------E 817
R + EEK ++RE ERER+R +EE+R AE+R RI++E + +
Sbjct: 291 ERARIEAEEKAAAQERERREAEERERMR----EEEKRAAEERQRIKEEEKRAAEERQRIK 346
Query: 818 QEKKREKEEEQRLKNEEHIRLAEERQK---EAERKKKEEEEKYNLQLQHYCERDNLIGEE 874
+E+KR EE QR+K EE R AEERQ+ E E K K EE+K N QL EE
Sbjct: 347 EEEKRAAEERQRIKEEEK-RAAEERQRARAEEEEKAKVEEQKRNKQL-----------EE 394
Query: 875 TKHMRQPSPIV-PALQNKIASKL--QRPPSVDSIIRSFIHESSMSRAQSPPVPARKNQLR 931
KH Q + I ++ KI K ++ D + + + + + V A++ +L+
Sbjct: 395 KKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTK--VQAKREKLQ 452
Query: 932 AEE---EKKNVIMELSEMRKQLRSEERRLQER---LLHMDSDDEIPIRKKERNPMDIFDM 985
++ +K+ + E + K+ + E + +R + S + + K ++ + F
Sbjct: 453 EDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSR 512
Query: 986 ARHRLQAPVRR-------QSPKGLDAATFQ----NVHDFNELKDRDSETRVDLKFMYLDP 1034
R + ++ K L+ + +F +LK + E ++L+ L
Sbjct: 513 PGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELE--ELKK 570
Query: 1035 PRDHHTLEIQQQALLREQQKRLNRIKMQEGAKVDLDAI----PSAKVREQRMPRDDTSD 1089
R+ ++++ R+Q++ +++ +E + + I A + Q+MP D SD
Sbjct: 571 KREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSD 629
Score = 60.8 bits (146), Expect = 8e-09
Identities = 105/604 (17%), Positives = 237/604 (39%), Gaps = 86/604 (14%)
Query: 633 QEALQQQIREREERRKKEREEKEEYEAKLEAEMRTYNPWGKGGGGAPLRDAKGNLITDLN 692
+ A +++ R R+ER ++++EE+ + + E+ N + D + T
Sbjct: 36 EAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQN---------SVPDEEAKTTTTNT 86
Query: 693 RMHRQNIDAYHNPDARTYE--DKRAVVSL-----------DPNLATSNAENLEDAANKSS 739
++ + A+ AR E KR +L D +L+ + D A +
Sbjct: 87 QVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENET 146
Query: 740 GHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLR--IAEE 797
+ +S E T + Q+ +++ + E+K++ EE E + R I E
Sbjct: 147 TEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGEN 206
Query: 798 KEERRLAEQRARIQQE------YEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKK 851
+ E + E+ Q+E + + K+EE+R + + I + + E E K++
Sbjct: 207 QVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEI--SHHEKMEEEDKER 264
Query: 852 EEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIH 911
E E+ L+ + ER+ + E+ K + + A + A + +R + + R +
Sbjct: 265 AEAERARLEAE---ERERIKAEQDKKIADERARIEAEEKAAAQERERREAEE---RERMR 318
Query: 912 ESSMSRAQSPPVPARKNQLRAEEEKKNVIME---LSEMRKQLRSEERRLQERLLHMDSDD 968
E RA ++ + RA EE++ + E +E R++++ EE+R E +++
Sbjct: 319 EEE-KRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEE 377
Query: 969 EIPIRKKERNPMDIFDMARHRLQAPVRRQSPKGLDAATFQNVHDFNELKDRDSETRVDLK 1028
E + +E+ + +H +Q ++K E +++ K
Sbjct: 378 EEKAKVEEQKRNKQLEEKKHAMQE---------------------TKIKGEKVEQKIEGK 416
Query: 1029 FMYLDPPRDH--HTLEIQQQALLREQQKRLNRIKMQEGAKV-DLDAIPSAKVREQRMPRD 1085
++ ++ T +++Q + + + R K+QE + I K+++ + P++
Sbjct: 417 WVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKE 476
Query: 1086 D-----------------TSDFLKNSLLESDSAFIGAYGETYPAIEDDVLPPPSQLPSAR 1128
+ +F+ + L +++ F G ++ P +
Sbjct: 477 EVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRL 536
Query: 1129 E---RRRNKWKGLDIDSSRPNVAPDGLSLKSISSVNVDELRVRNEERMRRLNEFHNKPIN 1185
E RRR + + + + + L L+ + + +V EE RR E ++ +
Sbjct: 537 EELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLR 596
Query: 1186 TDDE 1189
++E
Sbjct: 597 EEEE 600
Score = 56.6 bits (135), Expect = 1e-07
Identities = 78/343 (22%), Positives = 149/343 (43%), Gaps = 37/343 (10%)
Query: 620 DKPKPSKQSLQSYQEALQQQIREREERRKKEREEKEEYEA-KLEAEMRTYNPWGKGGGGA 678
++ K + Q + E ++Q+I + KK +E+K + K + E + G
Sbjct: 393 EEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEK----------GT 442
Query: 679 PLRDAKGNLITDLNRMHRQNI-DAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAANK 737
++ + L D ++ I D D E+ ++ + ++N E +K
Sbjct: 443 KVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHK 502
Query: 738 SSGHMQTQSSPFARGNVF-----GEPPTELQIKQQELYKNFLRFQIEE----KKQREEAE 788
T S P R +V G P E + +EL + + EE K++++EA
Sbjct: 503 LKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAA 562
Query: 789 RERLRIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNE---EHIRLAEERQKE 845
E + +++EERR + +++ EE K RE+EE++RLK E AE+RQK
Sbjct: 563 LELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKM 622
Query: 846 AERKKKEEEEKY--------NLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQ 897
E ++++ + +L+++ E N +++ ++ S A+ +KI S+L+
Sbjct: 623 PEDGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQKSSGVK--STHQAAIVSKIDSRLE 680
Query: 898 RPPSVDSIIRSFIHESSMSRAQSPPVPAR-KNQLRAEEEKKNV 939
+ S +S + + A PVPA +++ EK NV
Sbjct: 681 QYTSAIEGTKS--AKPTKPAASDLPVPAEGVRNIKSMWEKGNV 721
Score = 48.5 bits (114), Expect = 4e-05
Identities = 82/438 (18%), Positives = 184/438 (42%), Gaps = 74/438 (16%)
Query: 593 QPVVNTVGQNELKITSDQV------------INSGLIFEDKPKPSKQSLQ-----SYQEA 635
+P ++G+N++++ ++ + +G I ++PK ++ Q S+ E
Sbjct: 197 KPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEK 256
Query: 636 LQQQIREREE--RRKKEREEKEEYEAKLEAEMRTYNPWGKGGGGAPLRDAKGNLITDLNR 693
++++ +ER E R + E EE+E +A+ + ++ + A ++ + + R
Sbjct: 257 MEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERER 316
Query: 694 MHRQNIDAYHNPDARTYEDKRAV-----VSLDPNLATSNAENLEDAANKSSGHMQTQSSP 748
M + A E+KRA + + A + +++ +++ Q +
Sbjct: 317 MREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARA- 375
Query: 749 FARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEK------EERR 802
E + ++++Q+ K Q+EEKK + + + E+K E++
Sbjct: 376 --------EEEEKAKVEEQKRNK-----QLEEKKHAMQETKIKGEKVEQKIEGKWVNEKK 422
Query: 803 LAE---QRARIQQEYEEEQEK---KREKEEEQR--LKNEEHIRLAEERQKEAERKKKEEE 854
E Q A ++++ EE+ K KREK +E + K EE + +E+ K+ +++ KEE
Sbjct: 423 AQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEE---IKDEKIKK-DKEPKEEV 478
Query: 855 EKYNLQLQHYCERDNLIGE----ETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFI 910
+ + + + + E + GE + KH + + + P V++ R +
Sbjct: 479 KSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKR--L 536
Query: 911 HESSMSRAQSPPVPARK------------NQLRAEEEKKNVIMELSEMRKQLRSEERRLQ 958
E R ++ K +L+ + E++ ++E E R++ +R+L+
Sbjct: 537 EELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLR 596
Query: 959 ERLLHMDSDDEIPIRKKE 976
E +EI R+ E
Sbjct: 597 EEEEKRRLKEEIERRRAE 614
Score = 42.0 bits (97), Expect = 0.004
Identities = 60/314 (19%), Positives = 124/314 (39%), Gaps = 37/314 (11%)
Query: 151 TSETDPSTLGVSLPIGERLSAKERLKLERNKEYNQFLRGKEESSEKFRQVEKSTEPKSQR 210
T+E+ T+ +SL G+ S + + + ER E+ S++ EK E +R
Sbjct: 216 TTESQEETVVMSLKNGQISSEEPKQEEER-----------EQGSDEISHHEKMEEEDKER 264
Query: 211 NKKPIGQVKPDLTSQIQTSCENSEGPRKDVLTPSEAYEELLNQRRLEEDRYRQLDDEIEL 270
+ +++ + +I+ + + + E +RR E+R R ++E
Sbjct: 265 AEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEE--- 321
Query: 271 RNRRIIKKANEEVGISNLKHQRFASKAGIPDRRFHRFNEDRVFDRRYHRPDQDPEVSEEM 330
K+A EE +K + K +R+ + E R + R +++ +EE
Sbjct: 322 ------KRAAEE--RQRIKEE---EKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEER 370
Query: 331 DERFRYESDFDRRLSRVYTNDRMHRNKRGNMPPMEHDGDVIEQSNIRISSAENKSAPDNE 390
+R R E + ++ + RNK+ +E ++++ I+ E K
Sbjct: 371 -QRARAEEEEKAKV------EEQKRNKQ-----LEEKKHAMQETKIKGEKVEQKIEGKWV 418
Query: 391 TSKSANQDTCSPFAGMLFGGEDRELIQRRKEKYRLELLEQMAEQQRNKRREKDLELRVAA 450
K A +D G E +Q ++EK + + E+ ++++ +KD E +
Sbjct: 419 NEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEV 478
Query: 451 SGAQDPEKSPDRLK 464
D +K +K
Sbjct: 479 KSFMDRKKGFTEVK 492
Score = 36.2 bits (82), Expect = 0.20
Identities = 67/341 (19%), Positives = 130/341 (38%), Gaps = 44/341 (12%)
Query: 168 RLSAKERLKLERNK-EYNQFLRGKEESSEKFRQVEKSTEPKSQRNKKPIGQVKPDLTSQI 226
R +E ++LE + Y + +EE++ + R+ + + ++ ++ +GQV T Q+
Sbjct: 11 RRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQV----TDQV 66
Query: 227 QTSCENS---------------EGPRKDVLTPSEAYEELLNQRRLEEDRYRQ-------L 264
+ + +NS EG + A E Q+RL+E RQ
Sbjct: 67 EVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTIT 126
Query: 265 DDEIELRNRRIIKKANEEVGISNLKHQRFASKAGIPDRRFHRFNEDRVFDRRYHRPD-QD 323
D + L +RR+ E + K ++ S+ + + E + Y + D +D
Sbjct: 127 DASLSLPSRRMQNDTAENE--TTEKEEKSESR-----QERYEIEETETVTKSYQKNDWRD 179
Query: 324 PEVSEEMDERFRYESDFDRRLSRVYTNDRMHRNKRGNMPPMEHDGDVIEQSNIRISSAEN 383
E +++ D+ E + + + N ++ + + V+ N +ISS E
Sbjct: 180 AEENKKEDKEKEEEEEEKPKRGSIGEN-QVEVMVEEKTTESQEETVVMSLKNGQISSEE- 237
Query: 384 KSAPDNETSKSANQDTCSPFAGMLFGGEDRELIQRRKEKYRLELLEQMAEQQRNKRREKD 443
P E + D S M E+ + + E+ RLE E+ + ++ D
Sbjct: 238 ---PKQEEEREQGSDEISHHEKM----EEEDKERAEAERARLEAEERERIKAEQDKKIAD 290
Query: 444 LELRVAASGAQDPEKSPDRLKQFSVAPRHFEEMIPPERPRI 484
R+ A ++ R + R E+ ER RI
Sbjct: 291 ERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRI 331
Score = 36.2 bits (82), Expect = 0.20
Identities = 75/438 (17%), Positives = 166/438 (37%), Gaps = 80/438 (18%)
Query: 42 DEFIEEQKARLAEDKAELESDPPYMEMKGKLSAKLSENSKILISMAKENIPPNSQQTRGS 101
DE +K EDK E++ +E + + K ++ KI A+ +
Sbjct: 249 DEISHHEKME-EEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAA----- 302
Query: 102 LGIDYGLSLPLGEDYERKKHKLKEELRQDYRRYLTQGITQGKRKKNFLSTSETDPSTLGV 161
++ ER++ + +E +R++ +R ++ + E +
Sbjct: 303 -----------AQERERREAEERERMREEEKR--------AAEERQRIKEEEKRAAEERQ 343
Query: 162 SLPIGERLSAKERLKLE----RNKEYNQFLRGKEESSEKFRQVEKSTEPKSQRNKKPIGQ 217
+ E+ +A+ER +++ R E Q R +EE K + +++ + + +++ +
Sbjct: 344 RIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETK 403
Query: 218 VKPDLTSQIQTSCENSEGPRKDVLTPSEAYEELLNQRRLEEDRYRQLDDEIELRNRRIIK 277
+K + Q EG + +N+++ +ED+ + ++K
Sbjct: 404 IKGEKVEQ------KIEG-------------KWVNEKKAQEDKLQTA----------VLK 434
Query: 278 KANEEVGIS-NLKHQRFAS------KAGIPDRRFHRFNEDR-----VFDRRYHRPDQDPE 325
K EE G K ++ K I D + + E + DR+ + +
Sbjct: 435 KQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQ 494
Query: 326 VSEEMDERFRY-ESDFDRRLSRVYTNDRMHRNKRGNMPPMEHDGDVIEQSNIRISSAENK 384
E M + ++ E+ F R R + K P G +E+ R E++
Sbjct: 495 NGEFMTHKLKHTENTFSRPGGRASVD-----TKEAEGAPQVEAGKRLEELRRRRGETESE 549
Query: 385 SAPDNETSKSANQDTCSPFAGMLFGGEDR-ELIQRRKEKYRLELLEQMAEQQRNKRREKD 443
+ E K Q+ + E+R ++++ +++ + E ++ ++ KRR K+
Sbjct: 550 ---EFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKE 606
Query: 444 LELRVAASGAQDPEKSPD 461
R A A+ +K P+
Sbjct: 607 EIERRRAEAAEKRQKMPE 624
Score = 35.0 bits (79), Expect = 0.45
Identities = 39/175 (22%), Positives = 78/175 (44%), Gaps = 28/175 (16%)
Query: 785 EEAERERLRIAEEKEERRLAEQRARIQQEYEEEQE-----KKREKEEEQRLKNEEHI--R 837
++ ER R +++EE RL +R Q+ ++E+E ++R ++E R K EE +
Sbjct: 2 DDFERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQ 61
Query: 838 LAEERQKEAERKKKEEEEK---YNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIAS 894
+ ++ + A+ +EE K N Q++ +E + + + Q ++
Sbjct: 62 VTDQVEVNAQNSVPDEEAKTTTTNTQVEG--------DDEAAFLERLARREERRQKRLQE 113
Query: 895 KLQRPPSVDSIIRSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQ 949
L+R D I ++S+S +P+R+ Q E + E SE R++
Sbjct: 114 ALERQKEFDPTIT----DASLS------LPSRRMQNDTAENETTEKEEKSESRQE 158
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 76.6 bits (187), Expect = 1e-13
Identities = 53/226 (23%), Positives = 115/226 (50%), Gaps = 11/226 (4%)
Query: 761 ELQIKQQE---LYKNFLRFQIEEKKQREEA----ERERLRIAEEK--EERRLAEQRARIQ 811
E +I++QE + + ++ EEK +R+E + E++R EEK E+ ++ EQ + Q
Sbjct: 308 EEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQ 367
Query: 812 QEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCERDNLI 871
+E + +++KR+++E + + EE IR EE+ +E E +E+EEK Q + E++ +
Sbjct: 368 EEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEM 427
Query: 872 GEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPARKNQLR 931
E+ + MR+ + + KI + ++ + +++ E M +
Sbjct: 428 QEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQE--QEEKMGEQEGKMCEQEAKMQE 485
Query: 932 AEEEKKNVIMELSEMRKQLRSEERRLQERLLHMDSDDEIPIRKKER 977
EE+ + ++ E K++R +E +++E+ M +E ++E+
Sbjct: 486 QEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEK 531
Score = 75.9 bits (185), Expect = 2e-13
Identities = 52/208 (25%), Positives = 112/208 (53%), Gaps = 6/208 (2%)
Query: 765 KQQELYKNFLRFQIEEKKQREEAE--RERLRIAEEKEERRLAEQRARIQQEYEEEQEKKR 822
+Q+E + + + +EK+Q +EA+ R+ +I E++E+ R E+ + Q+E EQE+K
Sbjct: 361 EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKM 420
Query: 823 EKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPS 882
++EE+ + EE +R EE+ +E E+K +E+EEK Q + E++ +GE+ M +
Sbjct: 421 WEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQE 480
Query: 883 PIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIME 942
+ + K+ + ++ + IR + R Q + ++ ++ +EEK E
Sbjct: 481 AKMQEQEEKMRRQEEKIREQEKKIR---EQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE 537
Query: 943 -LSEMRKQLRSEERRLQERLLHMDSDDE 969
+ E +++R +E +++E+ + + +E
Sbjct: 538 KMQEQEEKMRRQEEKMREQEVRLRQQEE 565
Score = 75.5 bits (184), Expect = 3e-13
Identities = 79/346 (22%), Positives = 148/346 (42%), Gaps = 68/346 (19%)
Query: 619 EDKPKPSKQSLQSYQEALQQQ---IREREERRKKEREEKEEYEAKLEAEMRTYNPWGKGG 675
E+K ++ +Q +E +Q+Q IRE+EE+ +++ E E E K+ + W K
Sbjct: 287 EEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMM--WEKEE 344
Query: 676 GGAPLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAA 735
L + +MH Q R E+KR E + +
Sbjct: 345 KIRELEE----------KMHEQE-------KIREQEEKR-----------QEEEKIRE-- 374
Query: 736 NKSSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIA 795
Q K+QE R Q E+ +++EE RE+ +
Sbjct: 375 ---------------------------QEKRQEQEAKMWR-QEEKIREQEEKIREQEEMM 406
Query: 796 EEKEERRLAEQRARIQQEYEE--EQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEE 853
+E+EE+ + EQ ++ ++ EE EQE+K ++EE+ + E+ IR EE+ +E E +E+
Sbjct: 407 QEQEEK-MGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQ 465
Query: 854 EEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHES 913
EEK Q CE++ + E+ + MR+ + + KI + ++ + +++ E
Sbjct: 466 EEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQE--QEE 523
Query: 914 SMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLRSEERRLQE 959
M + + EE+ + ++ E +LR +E ++QE
Sbjct: 524 KMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569
Score = 70.5 bits (171), Expect = 1e-11
Identities = 60/232 (25%), Positives = 117/232 (50%), Gaps = 20/232 (8%)
Query: 761 ELQIKQQELYKNFLRFQIEEKKQREE---AERERLRIAEEKEERRLAEQRARIQQEYEEE 817
+ Q+++ EL+ N L Q EEK R+E ERE +I E++E+ R E++ R Q+E E
Sbjct: 270 QAQVEENELW-NRLNQQQEEKMWRQEEKIQEREE-KIQEQEEKIREQEEKMRRQEEMMWE 327
Query: 818 QEKKREKEEEQRLKNEEHIRLAEERQ------KEAERKKKEEE-----EKYNLQLQHYCE 866
+E+K ++EE + EE IR EE+ +E E K++EEE EK Q
Sbjct: 328 KEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWR 387
Query: 867 RDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPAR 926
++ I E+ + +R+ ++ + K+ + ++ + ++ + R Q + +
Sbjct: 388 QEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQ---EQEEKMRRQEEKIREQ 444
Query: 927 KNQLRAEEEKKNVIME-LSEMRKQLRSEERRLQERLLHMDSDDEIPIRKKER 977
+ ++R +EEK E + E +++ +E ++ E+ M +E R++E+
Sbjct: 445 EKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEK 496
Score = 55.8 bits (133), Expect = 2e-07
Identities = 88/419 (21%), Positives = 170/419 (40%), Gaps = 49/419 (11%)
Query: 589 HQLAQPVVNTVGQNELKITSDQVINSGLIFED-------KPKPSKQSLQSYQEALQQQIR 641
H P V T + T + IN+G E P+ +++ +QEAL++++
Sbjct: 59 HPQTNPSVGTAASD----TKKKKINNGTNPETTTSGGCHSPEDEQKASHQHQEALRRELE 114
Query: 642 EREERRKKEREEKEEYEA----------KLEAEMRT-----YNPWGKGGGGAPLRDAKGN 686
+ + + +K E + +LE E R ++ W G L A
Sbjct: 115 AQVQTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAG---ELEQALSA 171
Query: 687 LITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAANKSSGHMQTQS 746
+ T + R + DA + E R ++ D L NA+ E S + Q
Sbjct: 172 VATQKKKADRYIEELTKERDALSLELYRNTIT-DEELKEKNAKLQEKLQLVESEKSEIQL 230
Query: 747 S------PFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEE 800
+ R + P +LQ + L K + K Q + E E +++E
Sbjct: 231 NVKELKRKLERAKLL-LPQQQLQAEADHLGKELQ--SVSAKLQAQVEENELWNRLNQQQE 287
Query: 801 RRLAEQRARIQQEYE--EEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYN 858
++ Q +IQ+ E +EQE+K ++EE+ + EE + EE+ + E E+EEK
Sbjct: 288 EKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIR 347
Query: 859 LQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRA 918
+ E++ + +E K + + + +K+ R + IR + R
Sbjct: 348 ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ---EEKIR---EQEEKIRE 401
Query: 919 QSPPVPARKNQLRAEEEKK-NVIMELSEMRKQLRSEERRLQERLLHMDSDDEIPIRKKE 976
Q + ++ ++ +EEK E+ E +++R +E +++E+ + +E IR++E
Sbjct: 402 QEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEE-KIREQE 459
Score = 47.0 bits (110), Expect = 1e-04
Identities = 72/353 (20%), Positives = 146/353 (41%), Gaps = 35/353 (9%)
Query: 99 RGSLGIDYGLSLPLGEDYERKKHKLKEELR--QDYRRYLTQGITQGKRK----KNFLSTS 152
R +L ++ + E+ + K KL+E+L+ + + + + + KRK K L
Sbjct: 190 RDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQ 249
Query: 153 E--TDPSTLGVSLPIGERLSAKERLKLERNKEYNQFLRGKEESSEKFRQVEKSTEPKSQR 210
+ + LG L + +SAK + ++E N+ +N+ + +EE + + + E K Q
Sbjct: 250 QLQAEADHLGKEL---QSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQE 306
Query: 211 NKKPIGQVKPDLTSQIQTSCENSEGPRKDVLTPSEAYEELLNQRRLEEDRYRQLDDEIEL 270
++ I + + + Q + E E R+ E E++ R LEE + Q E
Sbjct: 307 QEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKI---RELEEKMHEQ-----EK 358
Query: 271 RNRRIIKKANEEVGISNLKHQRFASKAGIPDRRFHRFNEDRVFDRRYHRPDQDPEVSEEM 330
+ K+ EE K Q +K + + R E+++ ++ +Q+ ++ E+
Sbjct: 359 IREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKI-REQEEKIREQEEMMQEQEEKMGEQE 417
Query: 331 DERFRYESDFDRRLSRVYTNDRMHRNKRGNMPPMEHDGDVIEQSNIRISSAENKSAPDNE 390
++ + E + + ++ + R E + + EQ +I E E
Sbjct: 418 EKMWEQEEEMQEQEEKMRRQEEKIR---------EQEKKIREQEE-KIREQEEMMQEQEE 467
Query: 391 TSKSANQDTCSPFAGMLFGGEDRELIQRRKEKYRLELLEQMAEQQRNKRREKD 443
C A M E E ++R++EK R + E+ +Q K RE++
Sbjct: 468 KMGEQEGKMCEQEAKM---QEQEEKMRRQEEKIREQ--EKKIREQEEKIREQE 515
Score = 37.4 bits (85), Expect = 0.091
Identities = 69/408 (16%), Positives = 157/408 (38%), Gaps = 66/408 (16%)
Query: 42 DEFIEEQKARLAEDKAELESDPPYMEMKGKLSAKLSENSKILISMAKENIPPNSQQTRGS 101
DE ++E+ A+L E +ES+ +++ K + E +K+L +P Q
Sbjct: 204 DEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLL-------LPQQQLQAEAD 256
Query: 102 LGIDYGLSLPLGEDYERKKHKLKEELRQDYRRYLTQGITQGKRKKNFLSTSETDPSTLGV 161
LG++ + KL+ ++ ++ L + Q + +K +
Sbjct: 257 ---------HLGKELQSVSAKLQAQVEEN---ELWNRLNQQQEEKMW------------- 291
Query: 162 SLPIGERLSAKERLKLERNKEYNQFLRGKEESSEKFRQVEKSTEPKSQRNKKPIGQVKPD 221
R K + + E+ +E + +R +EE + ++ E K +R ++ + + K +
Sbjct: 292 ------RQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE-KEE 344
Query: 222 LTSQIQTSCENSEGPRKDVLTPSEAYEELLNQRRLEEDRYRQLDDEIELRNRRIIKKANE 281
+++ E R E E+ + ++ E RQ + R I++ E
Sbjct: 345 KIRELEEKMHEQEKIR-------EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEE 397
Query: 282 EVGISNLKHQRFASKAGIPDRRFHRFNEDRVFDRRYHRPDQDPEVSEEMDERFRYESDFD 341
++ Q K G E++++++ +Q+ ++ + ++ E
Sbjct: 398 KIREQEEMMQEQEEKMG--------EQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIR 449
Query: 342 RRLSRVYTNDRMHRNKRGNMPPMEHDGDVIEQSNIRISSAENKSAPDNETSKSANQDTCS 401
+ ++ + M + + M E +G + EQ ++ E K E + +
Sbjct: 450 EQEEKIREQEEMMQEQEEKMG--EQEGKMCEQ-EAKMQEQEEKMRRQEEKIREQEKKIRE 506
Query: 402 PFAGMLFGGEDRELIQRRKEKY------RLELLEQMAEQQRNKRREKD 443
+ E E++Q ++EK E E+M EQ+ RR+++
Sbjct: 507 QEEKI---REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE 551
Score = 35.8 bits (81), Expect = 0.26
Identities = 42/250 (16%), Positives = 111/250 (44%), Gaps = 36/250 (14%)
Query: 818 QEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEETKH 877
Q+KK ++ E+ K + + L R + + KE+ K +LQ + I K
Sbjct: 175 QKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKE 234
Query: 878 MRQ---------PSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPARKN 928
+++ P + A + + +LQ SV + +++ + E+ + N
Sbjct: 235 LKRKLERAKLLLPQQQLQAEADHLGKELQ---SVSAKLQAQVEENELW-----------N 280
Query: 929 QLRAEEEKKNVIME--LSEMRKQLRSEERRLQERLLHMDSDDEIPIRKKERNPMDIFDMA 986
+L ++E+K E + E ++++ +E +++E+ M +E+ K+E+ M
Sbjct: 281 RLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEK-------MR 333
Query: 987 RHRLQAPVRRQSPKGLDAATFQNVHDFNELKDRDSETRVDLKFMYLDPPRDHHTLEIQQQ 1046
R + + + L+ + +H+ ++++++ + + + K + ++ +Q+
Sbjct: 334 RQEEMMWEKEEKIRELE----EKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 389
Query: 1047 ALLREQQKRL 1056
+REQ++++
Sbjct: 390 EKIREQEEKI 399
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 76.3 bits (186), Expect = 2e-13
Identities = 81/357 (22%), Positives = 161/357 (45%), Gaps = 40/357 (11%)
Query: 619 EDKPKPSKQSLQSYQEALQQQIREREERRKK-EREEKEEYEAKL---EAEMRTYNP-WG- 672
E+K + ++++ +E QQ R E++ K E+E+ +E E K+ E ++R WG
Sbjct: 412 EEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQ 471
Query: 673 --KGGGGAPLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAEN 730
K +R+ + + +M Q + + +D+R
Sbjct: 472 EKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERL-------------RE 518
Query: 731 LEDAANKSSGHMQTQSSPFARGNVFGEPPTELQIK----QQELYKNFLRFQIEEKKQREE 786
E+ + Q + + E T+ Q K Q+E + R + EKK REE
Sbjct: 519 KEERMREQKKMWQQEEK------MREEKKTQEQEKKTWDQEEKMREEERMREREKKMREE 572
Query: 787 AERERLRIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEA 846
E R E++E+ + E++ R Q+E EQE+K +++EE+ + EE + EE K
Sbjct: 573 EEMMR----EQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQ 628
Query: 847 ERKKK--EEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDS 904
E+++ E+EEK Q + E++ + E+ + MR+ + + K+ + ++ +
Sbjct: 629 EQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEE 688
Query: 905 IIRSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLRSEERRLQERL 961
+R + R Q + ++ ++ +EEK E+ E +++R ++ ++QERL
Sbjct: 689 KMRE---QEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERL 742
Score = 74.7 bits (182), Expect = 5e-13
Identities = 88/381 (23%), Positives = 163/381 (42%), Gaps = 46/381 (12%)
Query: 622 PKPSKQSLQSYQEALQQQIREREERRKKEREEKEEYEAKLEAEMRTYNPWGKGGGGAPLR 681
P+ K++ +QEAL+++I ++ + +K E E L + G G +
Sbjct: 69 PEDEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGES-K 127
Query: 682 DAKGNL------ITDLNRMHRQNIDAYHNPDARTYED---KRAVVSLD--------PNLA 724
D G L +L R + +H R E+ +R +SL+ L
Sbjct: 128 DLAGRLHHSWHFAGELQRA-LSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELK 186
Query: 725 TSNAENLEDA--ANKSSGHMQTQSSPFARG---NVFGEPPTELQIKQQELYKNFLRFQIE 779
NAE E A +Q R F P + Q+E+++ + +
Sbjct: 187 KKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQ 246
Query: 780 EKKQREEAE---RERLRIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHI 836
EKK R++ E R+ R+ E++ + R E++ R Q++ EQEK+ +E+E+ L+ ++ +
Sbjct: 247 EKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKEL-REQEKELREQKKL 305
Query: 837 RLAEERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKL 896
R EE+ +E E K E+EEK Q + ++ + E+ K MR+ + K+ +
Sbjct: 306 REQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQ-------EQKMRDQE 358
Query: 897 QRPPSVDSIIRSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLRSEERR 956
+R D +R E M + ++ +EEK + E K++R EE
Sbjct: 359 ERMWEQDERLRE--KEERM---------REQEKMWEQEEKMQEEERIREREKKMREEEET 407
Query: 957 LQERLLHMDSDDEIPIRKKER 977
++E+ M +E ++E+
Sbjct: 408 MREQEEKMQKQEENMWEQEEK 428
Score = 71.6 bits (174), Expect = 4e-12
Identities = 53/223 (23%), Positives = 114/223 (51%), Gaps = 14/223 (6%)
Query: 757 EPPTELQIKQQELYKNFLRFQIEEKKQREEAER-----ERLRIAEEK---EERRLAEQRA 808
E +++ +++++++ R + +E K RE+ E+ +RLR E++ +E+ L EQ+
Sbjct: 245 EQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKK 304
Query: 809 -RIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCER 867
R Q+E +EQE+K ++EE+ + EE + EER E E++ +E+E+K Q + E+
Sbjct: 305 LREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQ 364
Query: 868 DNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPARK 927
D + E+ + MR+ + + K+Q + + E R Q + ++
Sbjct: 365 DERLREKEERMREQEKMW-----EQEEKMQEEERIREREKKMREEEETMREQEEKMQKQE 419
Query: 928 NQLRAEEEKKNVIMELSEMRKQLRSEERRLQERLLHMDSDDEI 970
+ +EEK+ L E +++L +E+ ++ + +++I
Sbjct: 420 ENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKI 462
Score = 70.1 bits (170), Expect = 1e-11
Identities = 72/376 (19%), Positives = 177/376 (47%), Gaps = 40/376 (10%)
Query: 619 EDKPKPSKQSLQSYQEALQQQ---IREREERRKKEREEKEEYEAKLEAEMRTYNPWGKGG 675
E + + +Q ++ +E + +Q +RE+EER + E+E+ E E K++ E R K
Sbjct: 344 EKQMREQEQKMRDQEERMWEQDERLREKEERMR-EQEKMWEQEEKMQEEERIREREKK-- 400
Query: 676 GGAPLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAA 735
+R+ + + +M +Q + + + + ++ +R + + E+
Sbjct: 401 ----MREEEETMREQEEKMQKQEENMWEQEE-KEWQQQRLPEQKEKLWEQEKMQEQEEKI 455
Query: 736 NKSSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAER-----E 790
+ ++ Q + + +++ ++ ++++ + + +E+K ++ ER E
Sbjct: 456 WEQEEKIRDQEEMWGQEKKMWRQE-KMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDE 514
Query: 791 RLRIAEEK--EERRLAEQRARIQQEYE-EEQEKK------REKEEEQRLKNEEHIRLAEE 841
RLR EE+ E++++ +Q ++++E + +EQEKK + +EEE+ + E+ +R EE
Sbjct: 515 RLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEE 574
Query: 842 RQKEAERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPS 901
+E E K +E+EEK Q + E++ + E+ + M + + + K+Q
Sbjct: 575 MMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE--KMWEQEEEDKMQEQEE 632
Query: 902 VDSIIRSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLRSEERRLQERL 961
+ + + Q + ++ ++R +EEK + E ++++ +E +++E+
Sbjct: 633 M------MWEQEEKMQEQEEKMWEQEEKMREQEEK------MREQEEKMQGQEEKMREQE 680
Query: 962 LHMDSDDEIPIRKKER 977
M +E ++E+
Sbjct: 681 EKMQGQEEKMREQEEK 696
Score = 59.7 bits (143), Expect = 2e-08
Identities = 61/274 (22%), Positives = 129/274 (47%), Gaps = 31/274 (11%)
Query: 619 EDKPKPSKQSLQSYQEALQQQ---IREREERRKKER-----EEKEEYEAKL-EAEMRTYN 669
E+K + +Q + +E + +Q +RE+EER ++++ EEK E K E E +T++
Sbjct: 492 EEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWD 551
Query: 670 PWGKGGGGAPLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAE 729
K +R+ + + + M R+ + + + E + + + + +
Sbjct: 552 QEEKMREEERMREREKKMREE-EEMMREQEEKMQEQEEKMREQEEKMWEQEEKM-----Q 605
Query: 730 NLEDAANKSSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAER 789
E+ + M Q E ++Q +++ +++ + Q +E+K E+ E+
Sbjct: 606 EQEEKMWEQEEKMWEQ-----------EEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEK 654
Query: 790 ERLRIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERK 849
R E++E+ R E++ + Q+E EQE+K + +EE+ + EE +R EE+ E K
Sbjct: 655 MR----EQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEK 710
Query: 850 KKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSP 883
+EEK Q + E++ I ++ + M++ P
Sbjct: 711 MWGQEEKMWGQ-EEMREKEERIRDQKEKMQERLP 743
Score = 42.0 bits (97), Expect = 0.004
Identities = 59/279 (21%), Positives = 117/279 (41%), Gaps = 37/279 (13%)
Query: 167 ERLSAKERLKLERNKEYNQFLRGKEESSEKFRQVEKSTEPKSQRNKKPIGQVKPDLTSQI 226
ERL KE E+ K + Q + +EE E+ R+ EK K + ++ + + + + Q
Sbjct: 366 ERLREKEERMREQEKMWEQEEKMQEE--ERIREREK----KMREEEETMREQEEKMQKQE 419
Query: 227 QTSCENSEGPRKDVLTPSEAYEELLNQRRLEEDRYRQLDDEIELRNRRIIKKANEEVGIS 286
+ E E + P E E+L Q +++E + + E ++R++ EE+
Sbjct: 420 ENMWEQEEKEWQQQRLP-EQKEKLWEQEKMQEQEEKIWEQEEKIRDQ-------EEMWGQ 471
Query: 287 NLKHQRFASKAGIPDRRFHRFNEDRVFDRRYHRPDQDPEVSEEMDERFRYESDFDRRLSR 346
K R D+ + + E+++ D+ DQ+ + E+ DER R + + R +
Sbjct: 472 EKKMWRQEKMREQEDQMWEQ--EEKMRDQEQKMWDQEERMWEQ-DERLREKEERMREQKK 528
Query: 347 VYTNDRMHRNKRGNMPPMEHDGDVIE--QSNIRISSAENKSAPDNETSKSANQDTCSPFA 404
++ + R ++ + D E + R+ E K + E +
Sbjct: 529 MWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMR----------- 577
Query: 405 GMLFGGEDRELIQRRKEKYRLELLEQMAEQQRNKRREKD 443
E E +Q ++EK R E E+M EQ+ + +++
Sbjct: 578 ------EQEEKMQEQEEKMR-EQEEKMWEQEEKMQEQEE 609
Score = 40.0 bits (92), Expect = 0.014
Identities = 57/286 (19%), Positives = 116/286 (40%), Gaps = 21/286 (7%)
Query: 167 ERLSAKERLKLERNKEYNQFLRGKEESSEKFRQVEKST-EPKSQRNKKPIGQVKPDLTSQ 225
E+L E K E + R E + QV+ +T + + R ++ + + + + Q
Sbjct: 194 EKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQ 253
Query: 226 IQTSCENSEGPRKDVLTPSEAYEELLNQ-RRLEEDRYRQLDDEIELRNRRIIKKANEEVG 284
+ E R+ E E++ Q +RL E + E ELR ++ +++ E++
Sbjct: 254 EEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQ 313
Query: 285 ISNLKHQRFASKAGIPDRRFHRFNEDRVFDRRYHRPDQDPEVSEEMDERFRYESDFDRRL 344
K K + + R E+R++++ +Q+ ++ ++ +
Sbjct: 314 EQEEKMWEQEEKMREQEEKMWR-QEERLWEQEKQMREQEQKMRDQEE------------- 359
Query: 345 SRVYTNDRMHRNKRGNMPPMEHDGDVIE--QSNIRISSAENKSAPDNETSKSANQDTCSP 402
R++ D R K M E + E Q RI E K + ET + +
Sbjct: 360 -RMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQ 418
Query: 403 FAGMLFGGEDRELIQRRKEKYRLELLEQ-MAEQQRNKRREKDLELR 447
M + E++E Q+R + + +L EQ ++Q K E++ ++R
Sbjct: 419 EENM-WEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIR 463
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 73.9 bits (180), Expect = 9e-13
Identities = 82/374 (21%), Positives = 171/374 (45%), Gaps = 32/374 (8%)
Query: 619 EDKPKPSKQSLQSYQEALQQQ---IREREERRKKEREE---KEEYEAKLEAEMRTYNP-- 670
E+K ++ +Q ++E +Q+Q IRE+EE+ +++ E+ +EE + E +MR
Sbjct: 299 EEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMM 358
Query: 671 WGKGGGGAPLRDA---KGNLITDLN-RMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATS 726
W K L + K I +L +MH Q + + + E+++ +
Sbjct: 359 WEKEEKMRRLEEMMWEKEEKIRELEEKMHEQ--EKIREQEEKRQEEEKIREQEKRQEQEA 416
Query: 727 NAENLEDAANKSSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREE 786
E+ + ++ Q R +++ +++ + + Q E+ +++EE
Sbjct: 417 KMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEE 476
Query: 787 AERERLRIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEA 846
R++ ++ E+E+ R E++ Q+E +QE+K ++EE+ + EE IR EE+ +E
Sbjct: 477 IWRQKEKM-HEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQ 535
Query: 847 ERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPI------VPALQNKIASKLQRPP 900
E K +E+EE Q + E++ + E+ K RQ I + + KI + ++
Sbjct: 536 EEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIW 595
Query: 901 SVDSIIRSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIME--------LSEMRKQLRS 952
+ IR + M + Q + ++ ++ +EEK E + E +LR
Sbjct: 596 EQEEKIR---EQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQ 652
Query: 953 EERRLQERLLHMDS 966
+E ++QE H+++
Sbjct: 653 QEEKMQEHQEHLEA 666
Score = 63.9 bits (154), Expect = 9e-10
Identities = 82/335 (24%), Positives = 150/335 (44%), Gaps = 55/335 (16%)
Query: 761 ELQIKQQELYKNFLRFQIEEKKQREEA---------ERERLRIAEEKEERRLAEQRARIQ 811
+ Q+++ EL+ N L Q EEK R+E + + +I E++E+ R E++ R Q
Sbjct: 282 QAQVEENELW-NRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQ 340
Query: 812 QEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCERDNLI 871
+E E+E+K ++EE + EE +R EE E E K +E EEK + E++ +
Sbjct: 341 EEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMH-------EQEKIR 393
Query: 872 GEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPARKNQLR 931
+E K + KI + +R + R + R Q + ++ ++
Sbjct: 394 EQEEKRQE---------EEKIREQEKRQEQEAKMWR----QEEKIREQEEKIREQEKKMW 440
Query: 932 AEEEKKNVIMELSEMRKQLRSEERRLQERLLHMDSDDEIPIRKKERNPMDIFDMARHRLQ 991
+EEK + ++ E K+ EE QE + + E R+KE+ H Q
Sbjct: 441 RQEEKIHEQEKIREEEKRQEQEEMWRQEEKIR---EQEEIWRQKEK---------MHE-Q 487
Query: 992 APVRRQSPKGLDAATFQNVHDFNELKDRDSETRVDLKFMYL----DPPRDHHTLEIQQQA 1047
+R+Q K + +HD E K R+ E ++ + + + R+ +Q+
Sbjct: 488 EKIRKQEEKVWRQE--EKMHD-QEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEE 544
Query: 1048 LLREQQKRL--NRIKMQEGAKVDLDAIPSAKVREQ 1080
+++EQ++++ KMQE K+ K+REQ
Sbjct: 545 MMQEQEEKMGEQEEKMQEQEKMRRQ---EEKIREQ 576
Score = 45.4 bits (106), Expect = 3e-04
Identities = 83/466 (17%), Positives = 177/466 (37%), Gaps = 52/466 (11%)
Query: 42 DEFIEEQKARLAEDKAELESDPPYMEMKGKLSAKLSENSKILISMAK-----ENIPPNSQ 96
DE ++E+ A+L E +ES+ +++ K + E +K+L+ + +++ Q
Sbjct: 216 DEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQ 275
Query: 97 QTRGSLGI---DYGLSLPLGEDYERKKHKLKEELRQDYRRYLTQGITQGKRKKNFLSTSE 153
L + L L + E K + +E++++ + Q ++++ E
Sbjct: 276 SVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEE 335
Query: 154 TDPSTLGVSLPIGERLSAKERLKLERNKEYNQFLRGKEESSEKFRQVE---------KST 204
+ E++ +E + E+ ++ + E EK R++E +
Sbjct: 336 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQ 395
Query: 205 EPKSQRNKKPIGQVK-----PDLTSQIQTSCENSEGPRKDVLTPSEAYEELLNQRRLEED 259
E K Q +K Q K + Q + E E R+ E++ Q ++ E+
Sbjct: 396 EEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREE 455
Query: 260 RYRQLDDEIELRNRRIIKKANEEVGISNLKHQRFASKAGIPDRRFHRFNEDRVFDRRYHR 319
RQ +E+ + +I + EE+ + K + ++ R E++V+ +
Sbjct: 456 EKRQEQEEMWRQEEKI--REQEEI---------WRQKEKMHEQEKIRKQEEKVWRQEEKM 504
Query: 320 PDQDPEVSEEMDERFRYESDFDRRLSRVYTNDRMHRNKRGNMPPM-----EHDGDVIEQS 374
DQ+ ++ E+ ++ +R E + ++ + R + M E + + EQ
Sbjct: 505 HDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQE 564
Query: 375 NIR-----ISSAENKSAPDNETSKSANQDTCSPFAGMLFGGEDRELIQRRKEKY------ 423
+R I E K E + + + E E++Q ++EK
Sbjct: 565 KMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKI---REQEEMMQEQEEKMWEQEEK 621
Query: 424 RLELLEQMAEQQRNKRREKDLELRVAASGAQDPEKSPDRLKQFSVA 469
E E+M EQ+ RR+++ Q EK + + A
Sbjct: 622 MCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAA 667
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 72.8 bits (177), Expect = 2e-12
Identities = 67/365 (18%), Positives = 163/365 (44%), Gaps = 16/365 (4%)
Query: 619 EDKPKPSKQSLQSYQEALQQQIREREERRKKEREEKE--EYEAKLEAEMRTYNPWGKGGG 676
+D+ K+ QE + +Q+ + E +K + +EK+ + E K++ E R K
Sbjct: 402 QDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKK--- 458
Query: 677 GAPLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAAN 736
+R+ + + +M +Q + + + + ++ +R + + E+
Sbjct: 459 ---MREEEETMREQEEKMQKQEENMWEQEE-KEWQQQRLPEQKEKLWEQEKMQEQEEKIW 514
Query: 737 KSSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAE 796
+ ++ Q + + +++ ++ ++++ + + +E+K ++ ER + E
Sbjct: 515 EQEEKIRDQEEMWGQEKKMWRQE-KMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQE 573
Query: 797 EKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEK 856
++++ E++ R ++E E+EKK +EEE + EE ++ EE+ +E E K E+EEK
Sbjct: 574 QEKKTWDQEEKMR-EEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEK 632
Query: 857 YNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKI--ASKLQRPPSVDSIIRSFIHESS 914
Q + E++ + E+ + M + + P + K+ K+Q + +
Sbjct: 633 MQEQEEKMWEQEEKMWEQEEKMWEQQRL-PEQKEKLWEHEKMQEQEKMQEQEEKIWEQEK 691
Query: 915 MSRAQSPPVPARKNQ--LRAEEEKKNVIMELSEMRKQLRSEERRLQERLLHMDSDDEIPI 972
M + +Q +R EE + ++ E + +R +E ++QE+ M +E
Sbjct: 692 MEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMW 751
Query: 973 RKKER 977
++E+
Sbjct: 752 EQEEK 756
Score = 71.6 bits (174), Expect = 4e-12
Identities = 56/230 (24%), Positives = 111/230 (48%), Gaps = 16/230 (6%)
Query: 758 PPTELQIKQQELYKNFLRFQIEEKKQREEAER-----ERLR-----IAEEKEERRLAEQR 807
P + Q+E+++ + +EKK R++ E+ ERLR + E++E+ E+R
Sbjct: 263 PQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKR 322
Query: 808 ARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCER 867
R Q++ EQEK+ +++E R + EE ++ EE+ E E K +E+EEK Q + E+
Sbjct: 323 LREQEKELREQEKELREQKELR-EQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQ 381
Query: 868 DNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPARK 927
+ + E+ + MR + ++ K +R + + E + + ++
Sbjct: 382 EKQMREQEQKMRDQEERMWEQDERLREKEERMREQEK-----MWEQVEKMREEKKMQEQE 436
Query: 928 NQLRAEEEKKNVIMELSEMRKQLRSEERRLQERLLHMDSDDEIPIRKKER 977
+ R +EEK + E K++R EE ++E+ M +E ++E+
Sbjct: 437 KKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEK 486
Score = 70.5 bits (171), Expect = 1e-11
Identities = 84/374 (22%), Positives = 158/374 (42%), Gaps = 42/374 (11%)
Query: 619 EDKPKPSKQSLQSYQEALQQQ--IREREERRKKEREEKEEYEAKLEAEMRTYNPWGKGGG 676
E K + ++ + +E +Q++ IRERE++ ++E E E E K++ + N W
Sbjct: 429 EKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEE--NMW----- 481
Query: 677 GAPLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAAN 736
+ R+ Q + + E+K E + D
Sbjct: 482 ------EQEEKEWQQQRLPEQKEKLWEQEKMQEQEEK----------IWEQEEKIRDQEE 525
Query: 737 K--SSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRF----QIEEKK--QREEAE 788
M Q + + E +++ ++Q+++ R Q +EKK +EE
Sbjct: 526 MWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKM 585
Query: 789 RERLRIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAER 848
RE R+ E +++ R E+ R Q+E +EQE+K +++EE+ + EE ++ EE+ E E
Sbjct: 586 REEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEE 645
Query: 849 KKKEEEEKYNLQLQHYCERDNL-----IGEETKHMRQPSPIVPALQNKIASKLQRPPSVD 903
K E+EEK Q + +++ L + E+ K Q I Q K+ K Q
Sbjct: 646 KMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWE--QEKMEKKTQEQEKKT 703
Query: 904 SIIRSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIME-LSEMRKQLRSEERRLQERLL 962
E SM R + + + +R +EEK E + E +++ +E ++ E+
Sbjct: 704 WDQEKMREEESM-REREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEE 762
Query: 963 HMDSDDEIPIRKKE 976
M +P +K++
Sbjct: 763 KMWEQQRLPEQKEK 776
Score = 65.9 bits (159), Expect = 2e-10
Identities = 81/448 (18%), Positives = 192/448 (42%), Gaps = 38/448 (8%)
Query: 619 EDKPKPSKQSLQSYQEALQQQIREREERRKKEREEKEEYEAKLEAEMRTYNPWGKGGGGA 678
++K ++ L+ +E +Q+Q + E+ +K RE++E+ + E W +
Sbjct: 333 QEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEE------RLWEQ---EK 383
Query: 679 PLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAANKS 738
+R+ + + RM Q+ + + R E ++ ++ + E
Sbjct: 384 QMREQEQKMRDQEERMWEQD-ERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQ 442
Query: 739 SGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEK 798
MQ + R E ++ +++++ K Q E ++EE E ++ R+ E+K
Sbjct: 443 EEKMQEEERIREREKKMREEEETMREQEEKMQK-----QEENMWEQEEKEWQQQRLPEQK 497
Query: 799 EERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYN 858
E+ E+ +++ E++EK R++EE + +E +E+ +E E + E+EEK
Sbjct: 498 EKLWEQEKMQEQEEKIWEQEEKIRDQEE---MWGQEKKMWRQEKMREQEDQMWEQEEKMR 554
Query: 859 LQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRA 918
Q Q +++ + ++T+ + + K++ + + E M R
Sbjct: 555 DQEQKMWDQEERMEKKTQEQEKKT-------WDQEEKMREEERMREREKKMREEEEMMRE 607
Query: 919 QSPPVPARKNQLRAEEEKK-NVIMELSEMRKQLRSEERRLQERLLHMDSDDEIPIRKKER 977
Q + ++ +++ +EEK ++ E +++ +E ++ E+ M +P +K++
Sbjct: 608 QEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEK- 666
Query: 978 NPMDIFDMARHRLQAPVRRQSPKGLDAATFQNVHDFNELKDRDSETRVDLKFMYLDPPRD 1037
+++ + + Q ++ Q K + + E K D E K + R+
Sbjct: 667 ----LWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQE-----KMREEESMRE 717
Query: 1038 HHTLEIQQQALLREQQKRL--NRIKMQE 1063
+++ ++REQ++++ KMQE
Sbjct: 718 REKKMREEEEMMREQEEKMQEQEEKMQE 745
Score = 64.3 bits (155), Expect = 7e-10
Identities = 71/326 (21%), Positives = 144/326 (44%), Gaps = 59/326 (18%)
Query: 768 ELYKNFL--------RFQIEEKKQREEAERERLRIAEEKEERRLAE--------QRARIQ 811
ELY+N + +++EK E+E+ +++ ++ +R+L Q +Q
Sbjct: 212 ELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQ 271
Query: 812 QEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCERDNLI 871
+E ++E+ RE+E++ R K EE + EER +E E K +E+EEK Q + E++ +
Sbjct: 272 EEMWRQEEELREQEKKIR-KQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKEL 330
Query: 872 GEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPARKNQLR 931
E+ K +R+ + + + Q + ++ ++R
Sbjct: 331 REQEKELREQ-------------------------KELREQEEQMQEQEEKMWEQEEKMR 365
Query: 932 AEEEKK-NVIMELSEMRKQLRSEERRLQERLLHMDSDDEIPIRKKERNPMDIFDM----A 986
+EEK L E KQ+R +E++++++ M DE +R+KE + M
Sbjct: 366 EQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDE-RLREKEERMREQEKMWEQVE 424
Query: 987 RHRLQAPVRRQSPKGLDAATFQNVHDFNELKDRDSETRVDLKFMYLDPPR---------D 1037
+ R + ++ Q K D + + + +++R+ + R + + M + +
Sbjct: 425 KMREEKKMQEQEKKTRDQE--EKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWE 482
Query: 1038 HHTLEIQQQALLREQQKRLNRIKMQE 1063
E QQQ L +++K + KMQE
Sbjct: 483 QEEKEWQQQRLPEQKEKLWEQEKMQE 508
Score = 64.3 bits (155), Expect = 7e-10
Identities = 70/364 (19%), Positives = 157/364 (43%), Gaps = 37/364 (10%)
Query: 619 EDKPKPSKQSLQSYQEALQQQIREREERRKKEREEKEEYEAKLEAEMRTYNPWGKGGGGA 678
E+K + +Q + +E ++++ +E+E++ + E+ E E E E +
Sbjct: 550 EEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKK------------ 597
Query: 679 PLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAANKS 738
+R+ + + +M Q + + + +E + + + + E E +
Sbjct: 598 -MREEEEMMREQEEKMQEQE-EKMQEQEEKMWEQEEKMQEQEEKMW----EQEEKMWEQE 651
Query: 739 SGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAER----ERLRI 794
+ Q P + ++ + Q K QE + + EKK +E+ ++ E++R
Sbjct: 652 EKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMR- 710
Query: 795 AEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEE- 853
E+E R E++ R ++E EQE+K +++EE+ + EE + EE+ E E K E+
Sbjct: 711 --EEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQ 768
Query: 854 ---EEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFI 910
E+K L + I E+ + MR + + K+ + ++ + + +
Sbjct: 769 RLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEE--KMWG 826
Query: 911 HESSMSRAQSPPVPARKNQLRAEEEKKNVIME-----LSEMRKQLRSEERRLQERLLHMD 965
E M Q + ++ ++ +EEK M+ + E +++R +E +++E+ M
Sbjct: 827 QEEKM-WGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMR 885
Query: 966 SDDE 969
+E
Sbjct: 886 GQEE 889
Score = 62.0 bits (149), Expect = 3e-09
Identities = 79/381 (20%), Positives = 163/381 (42%), Gaps = 66/381 (17%)
Query: 630 QSYQEALQQQI-REREERRKKEREEKEEYEAKLEAEMRTYNPWGKGGGGAPLRDAKGNLI 688
Q LQ+++ R+ EE R++E++ +++ E E R LR+ +G +
Sbjct: 264 QVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEER-------------LREQEGKMR 310
Query: 689 TDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAANKSSGHMQTQSSP 748
+M RQ + R E ++ + + L ++ + + +
Sbjct: 311 EQEEKMWRQ--------EKRLREQEKELREQEKELREQ-----KELREQEEQMQEQEEKM 357
Query: 749 FARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAER-----ERLRIAEEK----- 798
+ + E ++ +++ L++ + + +E+K R++ ER ERLR EE+
Sbjct: 358 WEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQE 417
Query: 799 ----------EERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEH-IRLAEERQKEAE 847
EE+++ EQ + + + E+ QE++R +E E++++ EE +R EE+ ++ E
Sbjct: 418 KMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQE 477
Query: 848 RKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIR 907
E+EEK Q Q E+ + E+ K Q I + KI + + + R
Sbjct: 478 ENMWEQEEK-EWQQQRLPEQKEKLWEQEKMQEQEEKIWEQ-EEKIRDQEEMWGQEKKMWR 535
Query: 908 SFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLRS-----------EERR 956
R Q + ++ ++R +E+K E E + Q + EE R
Sbjct: 536 -----QEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEER 590
Query: 957 LQERLLHMDSDDEIPIRKKER 977
++ER M ++E+ ++E+
Sbjct: 591 MREREKKMREEEEMMREQEEK 611
Score = 49.7 bits (117), Expect = 2e-05
Identities = 52/245 (21%), Positives = 111/245 (45%), Gaps = 25/245 (10%)
Query: 626 KQSLQSYQEALQQQIREREERRKKEREEKEEYEAKLEAEMRTYNPWGKGGGGAPLRDAKG 685
+Q L +E L + + +E+ + +E+EEK + K+E +T K +R+ +
Sbjct: 657 QQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEK--KTQEQEKKTWDQEKMREEES 714
Query: 686 NLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAANKSSGHMQTQ 745
+ + + R+ + + + E + + + + E E + + Q
Sbjct: 715 --MREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMW----EQEEKMWEQEEKMWEQQ 768
Query: 746 SSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAER-----ERLRIAEEK-- 798
P + ++ E +Q+++++ + + +E+K R + E+ E++R EEK
Sbjct: 769 RLPEQKEKLWEH---EKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMW 825
Query: 799 --EERRLAEQRARIQQE-----YEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKK 851
EE+ ++ QE EE+ E+K + +EE+ + EE +R EE+ +E E K +
Sbjct: 826 GQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMR 885
Query: 852 EEEEK 856
+EEK
Sbjct: 886 GQEEK 890
Score = 46.2 bits (108), Expect = 2e-04
Identities = 57/302 (18%), Positives = 129/302 (42%), Gaps = 50/302 (16%)
Query: 619 EDKPKPSKQSLQSYQEALQQQ---IREREERRKKEREEKEEYEAKL-EAEMRTYNPWGKG 674
E K + ++ ++ +E +Q+Q ++E+EE+ ++ E+ +E E K+ E E + + K
Sbjct: 595 EKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKM 654
Query: 675 GGGAPLRDAKGNL-----ITDLNRMHRQNIDAYHNP--DARTYEDKRAVVSLDPNLATSN 727
L + K L + + +M Q + + +T E ++ + +
Sbjct: 655 WEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEES 714
Query: 728 AENLEDAANKSSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKK----Q 783
E + M+ Q E ++Q +++E+++ + +E+K Q
Sbjct: 715 MREREKKMREEEEMMREQEEKMQ------EQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQ 768
Query: 784 REEAERERL----------RIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNE 833
R ++E+L +I E++E+ R E++ R Q+E QE+K +EE+ E
Sbjct: 769 RLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQE 828
Query: 834 EHI-------------------RLAEERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEE 874
E + ++ E+ Q + E+ +++EE+ + + + + + G+E
Sbjct: 829 EKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQE 888
Query: 875 TK 876
K
Sbjct: 889 EK 890
Score = 39.3 bits (90), Expect = 0.024
Identities = 54/303 (17%), Positives = 126/303 (41%), Gaps = 16/303 (5%)
Query: 167 ERLSAKERLKLERNKEYNQFLRGKEESSEKFRQVEKSTEPKSQR--NKKPIGQVKPDLTS 224
ERL KE E+ K + Q + +EE +K ++ EK T + ++ ++ I + + +
Sbjct: 404 ERLREKEERMREQEKMWEQVEKMREE--KKMQEQEKKTRDQEEKMQEEERIREREKKMRE 461
Query: 225 QIQTSCENSEGPRKDVLTPSEAYEELLNQRRLEEDRYRQLDDEIELRNRRIIKKANEEVG 284
+ +T E E +K E E+ Q+RL E + + + E I + E++
Sbjct: 462 EEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKI- 520
Query: 285 ISNLKHQRFASKAGIPDRRFHRFNEDRVFDRRYHRPDQDPEVSEEMDERFRYESDFDRRL 344
+ + + + + + R ED+++++ DQ+ ++ ++ + + + +++
Sbjct: 521 --RDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKT 578
Query: 345 SRVYTNDRMHRNKRGNMPPMEHDGDVIEQSNIRISSAENKSAP------DNETSKSANQD 398
R R M + +++ + ++ E K + E ++
Sbjct: 579 WDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEE 638
Query: 399 TCSPFAGMLFGGEDRELIQRR--KEKYRLELLEQMAEQQR-NKRREKDLELRVAASGAQD 455
++ E++ Q+R ++K +L E+M EQ++ ++ EK E Q+
Sbjct: 639 KMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQE 698
Query: 456 PEK 458
EK
Sbjct: 699 QEK 701
Score = 31.2 bits (69), Expect = 6.5
Identities = 55/310 (17%), Positives = 124/310 (40%), Gaps = 27/310 (8%)
Query: 175 LKLERNKEYNQFLRGKEESSEKFRQVEKSTEPKSQRNKKPIGQVKPD---LTSQIQTSCE 231
L+L RN N+ L+ K ++ + +S + + Q N K + + L Q+QT+
Sbjct: 211 LELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTL 270
Query: 232 NSEGPRKDVLTPSEAYEELLNQRRLEEDRYRQLDDEIELRNRRIIKKANEEVGISNLKHQ 291
E R++ E E+ R+ EE +RQ E LR + + EE K
Sbjct: 271 QEEMWRQE----EELREQEKKIRKQEEKMWRQ---EERLREQEGKMREQEEKMWRQEKRL 323
Query: 292 RFASKAGIPDRRFHRFNEDRVFDRRYHRPDQDPEVSEEMDERFRYESDFDRRLSRVYTND 351
R K + ++ + + ++ +Q+ ++ E+ ++ E R+ R++ +
Sbjct: 324 REQEKE-LREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQE 382
Query: 352 RMHRNKRGNMPPMEHDGDVIEQSNIRISSAENKSAPDNETSKSANQDTCSPFAGMLFGGE 411
+ R + M E + + + + R+ E + + + + E
Sbjct: 383 KQMREQEQKMRDQE---ERMWEQDERLREKEERMREQEKMWEQVEKMR-----------E 428
Query: 412 DRELIQRRKEKYRLELLEQMAEQQRNKRREKDLELRVAASGAQDPEKSPDRLKQFSVAPR 471
++++ ++ K+ E E+M E++R + REK + Q+ + + +
Sbjct: 429 EKKMQEQEKKTRDQE--EKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEK 486
Query: 472 HFEEMIPPER 481
+++ PE+
Sbjct: 487 EWQQQRLPEQ 496
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 72.8 bits (177), Expect = 2e-12
Identities = 67/344 (19%), Positives = 155/344 (45%), Gaps = 29/344 (8%)
Query: 639 QIREREERRKKEREEKEEYEAKL-EAEMRTYNPWGKGGGGAPLRDAKGNLITDLNRMHRQ 697
Q+RE+E + +++ + E E ++ E E + G+ +R+ +G + ++ Q
Sbjct: 116 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ------VREQEGQVREQEGQVREQ 169
Query: 698 NIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAANKSSGHMQTQSSPFARGNVFGE 757
+ + E + V + + + E Q Q G
Sbjct: 170 E-GQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGE---- 224
Query: 758 PPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEK----EERRLAEQRARIQQE 813
E Q+++QE Q+++++++ + + E++R EE+ EE+ ++ ++Q+
Sbjct: 225 --QEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQK 282
Query: 814 YEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCERDNLIGE 873
+ EQE++ ++EEQ + EE +R EE+ +E E + +E+EE+ Q + E+ + E
Sbjct: 283 EQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWE 342
Query: 874 ETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPARKNQLRAE 933
+ + M + + ++ + ++ + +R + R Q + ++ Q+R +
Sbjct: 343 QKEQMWKQ-------EEQMGEQEEQMQKQEEQVRK---QEEQMRKQEEQMRKQEEQMRKQ 392
Query: 934 EEKKNVIME-LSEMRKQLRSEERRLQERLLHMDSDDEIPIRKKE 976
EE+ E + E ++Q+R +E ++ E+ M +E +KE
Sbjct: 393 EEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
Score = 60.1 bits (144), Expect = 1e-08
Identities = 51/266 (19%), Positives = 120/266 (45%), Gaps = 48/266 (18%)
Query: 619 EDKPKPSKQSLQSYQEAL---QQQIREREERRKKEREEKEEYEAKLEAEMRTYNPWGKGG 675
E++ ++ +Q +E + ++Q+R++EE+ ++ E+ ++ E +++ +
Sbjct: 205 EEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQE---------- 254
Query: 676 GGAPLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAA 735
+M +Q + ++++ + + E+
Sbjct: 255 ----------------EQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQM 298
Query: 736 NKSSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEK-KQREEAERERLRI 794
+ M+ Q E Q+++QE +R Q E+ KQ E+ ++ ++
Sbjct: 299 REQEEQMREQ---------------EEQMREQE---EQMREQEEQMGKQEEQMWEQKEQM 340
Query: 795 AEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEE 854
E+KE+ E++ Q+E ++QE++ K+EEQ K EE +R EE+ ++ E + E++
Sbjct: 341 WEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQK 400
Query: 855 EKYNLQLQHYCERDNLIGEETKHMRQ 880
E+ Q + E++ +GE+ + MR+
Sbjct: 401 EQMGEQKEQMREQEEQMGEQKEQMRK 426
Score = 51.2 bits (121), Expect = 6e-06
Identities = 64/415 (15%), Positives = 167/415 (40%), Gaps = 13/415 (3%)
Query: 777 QIEEKKQREEAERERLRIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEE-H 835
+++E+ Q E E+ +++ ++ +R+L + + QE + +++ + +E+E +++ +E
Sbjct: 15 ELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVREQEGQ 74
Query: 836 IRLAEERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASK 895
+R E + +E E + +E+E + Q E++ + E+ +R+ V + ++ +
Sbjct: 75 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 134
Query: 896 LQRPPSVDSIIR----SFIHESSMSRAQSPPVPARKNQLRAEE----EKKNVIME----L 943
+ + +R + R Q V ++ Q+R +E E++ + E +
Sbjct: 135 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQM 194
Query: 944 SEMRKQLRSEERRLQERLLHMDSDDEIPIRKKERNPMDIFDMARHRLQAPVRRQSPKGLD 1003
E Q+ +E ++ E+ M +E ++E+ M Q + + + +
Sbjct: 195 GEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQE 254
Query: 1004 AATFQNVHDFNELKDRDSETRVDLKFMYLDPPRDHHTLEIQQQALLREQQKRLNRIKMQE 1063
+ E +++ E + ++ T E ++Q +E+Q R +M+E
Sbjct: 255 EQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMRE 314
Query: 1064 GAKVDLDAIPSAKVREQRMPRDDTSDFLKNSLLESDSAFIGAYGETYPAIEDDVLPPPSQ 1123
+ + +E++M + + + +G E E+ V Q
Sbjct: 315 QEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQ 374
Query: 1124 LPSARERRRNKWKGLDIDSSRPNVAPDGLSLKSISSVNVDELRVRNEERMRRLNE 1178
+ E+ R + + + + + + + +E +E+MR+ E
Sbjct: 375 MRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEE 429
Score = 50.8 bits (120), Expect = 8e-06
Identities = 51/310 (16%), Positives = 130/310 (41%), Gaps = 32/310 (10%)
Query: 759 PTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERRLAEQRARIQQEYEEEQ 818
P E Q+++QE + ++Q + + ++ E++ + R E + R Q+ EQ
Sbjct: 49 PQEGQVREQE---------GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 99
Query: 819 EKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEETKHM 878
E + ++E Q + E +R E + +E E + +E+E + Q E++ + E+ +
Sbjct: 100 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 159
Query: 879 RQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPARKNQLRAEEEKKN 938
R+ V + ++ + + + +R E M + + EE+ +
Sbjct: 160 REQEGQVREQEGQVREQEGQVREQEGQVRE--QEGQMGEQEGQMGEQEEQMGEQEEQMQK 217
Query: 939 VIMELSEMRKQLRSEERRLQERLLHMDSDD------EIPIRKKERNPMDIFDMARHRLQA 992
++ E +Q+R +E ++ E+ + + E +RK+E + + R + +
Sbjct: 218 QEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQ 277
Query: 993 PVRRQSPKGLDAATFQNVHDFNELKDRDSETRVDLKFMYLDPPRDHHTLEIQQQALLREQ 1052
++++ + T + E +++ E ++ +Q+ +REQ
Sbjct: 278 MLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMR---------------EQEEQMREQ 322
Query: 1053 QKRLNRIKMQ 1062
++++ + + Q
Sbjct: 323 EEQMGKQEEQ 332
Score = 50.4 bits (119), Expect = 1e-05
Identities = 42/256 (16%), Positives = 111/256 (43%), Gaps = 54/256 (21%)
Query: 619 EDKPKPSKQSLQSYQEALQQQIREREERRKKEREEKEEYEAKLEAEMRTYNPWGKGGGGA 678
E++ ++ +Q +E Q++++EE+ +K+ E+ E E +
Sbjct: 233 EEQMGEQEEQVQKQEE----QVQKQEEQMRKQEEQMREQEEQ------------------ 270
Query: 679 PLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAANKS 738
+R+ + ++ + ++ R E++ E+ +
Sbjct: 271 -MREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQ--------------MREQEEQMREQ 315
Query: 739 SGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEK 798
M+ Q G+ ++ +++++++ Q+E+ ++ ++ E++
Sbjct: 316 EEQMREQEEQ------MGKQEEQMWEQKEQMWE-----------QKEQMWKQEEQMGEQE 358
Query: 799 EERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYN 858
E+ + E++ R Q+E +QE++ K+EEQ K EE + +E+ E + + +E+EE+
Sbjct: 359 EQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMG 418
Query: 859 LQLQHYCERDNLIGEE 874
Q + +++ +GE+
Sbjct: 419 EQKEQMRKQEEHMGEQ 434
Score = 49.7 bits (117), Expect = 2e-05
Identities = 53/311 (17%), Positives = 135/311 (43%), Gaps = 17/311 (5%)
Query: 760 TELQIKQQELYKNFLRFQI------EEKKQREEAERERLRIAEEKEERRLAEQRARIQQE 813
+E+Q+ +EL + +I + ++Q + + ++ E++ + R E + R Q+
Sbjct: 28 SEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 87
Query: 814 YEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCERDNLIGE 873
EQE + ++E Q + E +R E + +E E + +E+E + Q E++ + E
Sbjct: 88 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 147
Query: 874 ETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPARKNQLRAE 933
+ +R+ V + ++ + + + +R + R Q + ++ Q+ +
Sbjct: 148 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVR---EQEGQVREQEGQMGEQEGQMGEQ 204
Query: 934 EEKKNVIMELSEMRKQLRSEERRLQERLLHMDSDDEIPIRKKERNPMDIFDMARHRLQAP 993
EE ++ E +Q++ +E ++ E+ M +E ++E+ + + Q
Sbjct: 205 EE------QMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQ-- 256
Query: 994 VRRQSPKGLDAATFQNVHDFNELKDRDSETRVDLKFMYLDPPRDHHTLEIQQQALLREQQ 1053
+R+Q + + + LK ++ + + + R+ +Q+ +REQ+
Sbjct: 257 MRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQE 316
Query: 1054 KRLNRIKMQEG 1064
+++ + Q G
Sbjct: 317 EQMREQEEQMG 327
Score = 32.3 bits (72), Expect = 2.9
Identities = 28/181 (15%), Positives = 85/181 (46%), Gaps = 6/181 (3%)
Query: 165 IGERLSAKERLKLERNKEYNQFLRGKEESSEKFRQVEKSTEPKSQRNKKPIGQVKPDLTS 224
+GE+ ++ + + ++ Q + +E+ E+ QV+K E + Q+ ++ + + + +
Sbjct: 208 MGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQ-EEQVQKQEEQMRKQEEQMRE 266
Query: 225 QIQTSCENSEG--PRKDVLTPSEAYEELLNQRRLEEDRYRQLDDEIELRNRRIIKKANEE 282
Q + E E +K+ E E Q R +E++ R+ ++++ + + +++ E+
Sbjct: 267 QEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQ-MREQEEQ 325
Query: 283 VGISNLKHQRFASKAGIPDRRFHRFNEDRVFDRRYHRPDQDPEVSEEMDERFRYESDFDR 342
+G + Q + K + +++ + ++ + + + E + +E+ R + + R
Sbjct: 326 MG--KQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMR 383
Query: 343 R 343
+
Sbjct: 384 K 384
>gi|239735584 TRAF2 and NCK interacting kinase isoform 4 [Homo
sapiens]
Length = 1323
Score = 70.1 bits (170), Expect = 1e-11
Identities = 51/193 (26%), Positives = 91/193 (47%), Gaps = 23/193 (11%)
Query: 753 NVFGEPPTELQIK-QQELYKNFLRFQIEEKKQREEAERERL------------------- 792
N GEP + L + + L ++FLR Q+ K++ E R++L
Sbjct: 333 NDSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQ 392
Query: 793 -RIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKK 851
RI E+KE+RR E++ R ++E ++QE+++ + E++++ EE R AE Q+ ++ +
Sbjct: 393 KRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYKRKQLE 452
Query: 852 EEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIH 911
E+ + LQ Q ERD L+ +H RQ V + P + +
Sbjct: 453 EQRQAERLQRQLKQERDYLV--SLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEVEE 510
Query: 912 ESSMSRAQSPPVP 924
S ++R SP +P
Sbjct: 511 RSRLNRQSSPAMP 523
Score = 44.3 bits (103), Expect = 7e-04
Identities = 68/310 (21%), Positives = 121/310 (39%), Gaps = 47/310 (15%)
Query: 743 QTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERR 802
Q PF R + P E Q++ Q K+ + +++ +++E E E EE+EE
Sbjct: 282 QLMKHPFIR-----DQPNERQVRIQ--LKDHIDRTKKKRGEKDETEYEYSGSEEEEEEND 334
Query: 803 LAEQRA---------------RIQQEYEEEQEK-KREKEEEQRLKNEEHIR-LAEERQKE 845
E + R+Q +E E +R++ E+Q+ +NEEH R L ERQK
Sbjct: 335 SGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKR 394
Query: 846 AE-----RKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASK-LQRP 899
E R++ EE+++ +L+ ER+ E + R+ + + K L+
Sbjct: 395 IEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYKRKQLEEQ 454
Query: 900 PSVDSIIRSFIHES----SMSRAQSPPVPARKNQL------RAEEEKKNVIMELSEMRKQ 949
+ + R E S+ + P K L + EK E+ E +
Sbjct: 455 RQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEVEERSRL 514
Query: 950 LRSEERRLQERLLHMDSDDEIPIRKKERNPMDIFDMARHRLQAPVRRQSP-------KGL 1002
R + ++ + SD +P R + + + + PV Q P +G
Sbjct: 515 NRQSSPAMPHKVANRISDPNLPPRSESFSISGVQPARTPPMLRPVDPQIPHLVAVKSQGP 574
Query: 1003 DAATFQNVHD 1012
Q+VH+
Sbjct: 575 ALTASQSVHE 584
Score = 32.3 bits (72), Expect = 2.9
Identities = 13/48 (27%), Positives = 29/48 (60%)
Query: 617 IFEDKPKPSKQSLQSYQEALQQQIREREERRKKEREEKEEYEAKLEAE 664
+ ++ K ++ + + +QQ RE+E R+++ERE++ YE ++ E
Sbjct: 387 LLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRRE 434
Score = 31.6 bits (70), Expect = 5.0
Identities = 90/434 (20%), Positives = 162/434 (37%), Gaps = 56/434 (12%)
Query: 412 DRELIQRRKEKYRLELLEQMAEQQRNKRREKDLEL-RVAASGAQDPEKSPDRLKQ---FS 467
++EL ++++ + R EQM ++ +R E + E R + E+ +LKQ +
Sbjct: 412 EKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYKRKQLEEQRQAERLQRQLKQERDYL 471
Query: 468 VAPRH-FEEMIPPERPRIAFQTPLPPLSAPSVPPIPSVHPVPSQNEDLRSGLSSALGEMV 526
V+ +H +E P E+ PL PS P ++ + RS L+ +
Sbjct: 472 VSLQHQRQEQRPVEK---------KPLYHYKEGMSPSEKPAWAKEVEERSRLNRQSSPAM 522
Query: 527 SPRIAPLPPPPLLPPLATNYRTPYDDAYYFYGSRNTFDPSLAYYGSGMMGVQPAAYVSAP 586
++A P LPP + ++ DP + + + + Q A ++
Sbjct: 523 PHKVANRISDPNLPPRSESFSISGVQPARTPPMLRPVDPQIPHLVA--VKSQGPALTASQ 580
Query: 587 VTHQLAQPVVNTVG-QNELKITSDQV----INSGLIFEDKPKPSKQSLQSYQEALQQQIR 641
H+ QP G Q L +TS +V NS E+ P P++
Sbjct: 581 SVHE--QPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTR--------------I 624
Query: 642 EREERRKKEREEKEEYEAKLEAEMRTYNPWGKGGGGAPLRDAKGNLITDLNRMHRQNIDA 701
E+ +R R+E E+ K+ + +P +++ GN R+ Q I A
Sbjct: 625 EKFDRSSWLRQE-EDIPPKVPQRTTSISP------ALARKNSPGNGSALGPRLGSQPIRA 677
Query: 702 YHNPDARTYEDKRAVVSLDPNLATSNAENLEDAANKSSGHMQTQSSPFARGNVFGEPPTE 761
NPD R E + P TS+ + + S Q S P ++
Sbjct: 678 -SNPDLRRTEP----ILESPLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVR 732
Query: 762 LQIKQQ---ELYKNFLRFQIEEKKQ--REEAERERLRIAEEKEERRLAEQRARIQQ--EY 814
K + L + + EE + R + +A+E E R+ E +++ +Y
Sbjct: 733 ANSKSEGSPVLPHEPAKVKPEESRDITRPSRPADLTALAKELRELRIEETNRPMKKVTDY 792
Query: 815 EEEQEKKREKEEEQ 828
E+ EEE+
Sbjct: 793 SSSSEESESSEEEE 806
>gi|239735582 TRAF2 and NCK interacting kinase isoform 3 [Homo
sapiens]
Length = 1331
Score = 70.1 bits (170), Expect = 1e-11
Identities = 51/193 (26%), Positives = 91/193 (47%), Gaps = 23/193 (11%)
Query: 753 NVFGEPPTELQIK-QQELYKNFLRFQIEEKKQREEAERERL------------------- 792
N GEP + L + + L ++FLR Q+ K++ E R++L
Sbjct: 333 NDSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQ 392
Query: 793 -RIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKK 851
RI E+KE+RR E++ R ++E ++QE+++ + E++++ EE R AE Q+ ++ +
Sbjct: 393 KRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYKRKQLE 452
Query: 852 EEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIH 911
E+ + LQ Q ERD L+ +H RQ V + P + +
Sbjct: 453 EQRQAERLQRQLKQERDYLV--SLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEVEE 510
Query: 912 ESSMSRAQSPPVP 924
S ++R SP +P
Sbjct: 511 RSRLNRQSSPAMP 523
Score = 44.3 bits (103), Expect = 7e-04
Identities = 68/310 (21%), Positives = 121/310 (39%), Gaps = 47/310 (15%)
Query: 743 QTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERR 802
Q PF R + P E Q++ Q K+ + +++ +++E E E EE+EE
Sbjct: 282 QLMKHPFIR-----DQPNERQVRIQ--LKDHIDRTKKKRGEKDETEYEYSGSEEEEEEND 334
Query: 803 LAEQRA---------------RIQQEYEEEQEK-KREKEEEQRLKNEEHIR-LAEERQKE 845
E + R+Q +E E +R++ E+Q+ +NEEH R L ERQK
Sbjct: 335 SGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKR 394
Query: 846 AE-----RKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASK-LQRP 899
E R++ EE+++ +L+ ER+ E + R+ + + K L+
Sbjct: 395 IEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYKRKQLEEQ 454
Query: 900 PSVDSIIRSFIHES----SMSRAQSPPVPARKNQL------RAEEEKKNVIMELSEMRKQ 949
+ + R E S+ + P K L + EK E+ E +
Sbjct: 455 RQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEVEERSRL 514
Query: 950 LRSEERRLQERLLHMDSDDEIPIRKKERNPMDIFDMARHRLQAPVRRQSP-------KGL 1002
R + ++ + SD +P R + + + + PV Q P +G
Sbjct: 515 NRQSSPAMPHKVANRISDPNLPPRSESFSISGVQPARTPPMLRPVDPQIPHLVAVKSQGP 574
Query: 1003 DAATFQNVHD 1012
Q+VH+
Sbjct: 575 ALTASQSVHE 584
Score = 32.3 bits (72), Expect = 2.9
Identities = 13/48 (27%), Positives = 29/48 (60%)
Query: 617 IFEDKPKPSKQSLQSYQEALQQQIREREERRKKEREEKEEYEAKLEAE 664
+ ++ K ++ + + +QQ RE+E R+++ERE++ YE ++ E
Sbjct: 387 LLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRRE 434
Score = 31.6 bits (70), Expect = 5.0
Identities = 82/431 (19%), Positives = 165/431 (38%), Gaps = 42/431 (9%)
Query: 412 DRELIQRRKEKYRLELLEQMAEQQRNKRREKDLEL-RVAASGAQDPEKSPDRLKQ---FS 467
++EL ++++ + R EQM ++ +R E + E R + E+ +LKQ +
Sbjct: 412 EKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYKRKQLEEQRQAERLQRQLKQERDYL 471
Query: 468 VAPRH-FEEMIPPERPRIAFQTPLPPLSAPSVPPIPSVHPVPSQNEDLRSGLSSALGEMV 526
V+ +H +E P E+ PL PS P ++ + RS L+ +
Sbjct: 472 VSLQHQRQEQRPVEK---------KPLYHYKEGMSPSEKPAWAKEVEERSRLNRQSSPAM 522
Query: 527 SPRIAPLPPPPLLPPLATNYRTPYDDAYYFYGSRNTFDPSLAYYGSGMMGVQPAAYVSAP 586
++A P LPP + ++ DP + + + + Q A ++
Sbjct: 523 PHKVANRISDPNLPPRSESFSISGVQPARTPPMLRPVDPQIPHLVA--VKSQGPALTASQ 580
Query: 587 VTHQLAQPVVNTVG-QNELKITSDQV----INSGLIFEDKPKPSKQSLQSYQEALQQQIR 641
H+ QP G Q L +TS +V NS E+ P P++ ++ + + +R
Sbjct: 581 SVHE--QPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTR--IEKFDRS--SWLR 634
Query: 642 EREERRKKEREEKEEYEAKLEAEMRTYNPWGKGG--GGAPLRDAKGNLITDLNRMHRQNI 699
+ E+ K + L + N G G P+R + +L R+
Sbjct: 635 QEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDL--------RRTE 686
Query: 700 DAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAANKSSGHMQTQSSPFARGNVFGEPP 759
+P RT + S + +S + + SS + +++ + G+ P
Sbjct: 687 PILESPLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPV-LPH 745
Query: 760 TELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERRLAEQRARIQQ--EYEEE 817
++K +E + ++ + + +A+E E R+ E +++ +Y
Sbjct: 746 EPAKVKPEE--SRDITRPSRPASYKKAIDEDLTALAKELRELRIEETNRPMKKVTDYSSS 803
Query: 818 QEKKREKEEEQ 828
E+ EEE+
Sbjct: 804 SEESESSEEEE 814
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 68.9 bits (167), Expect = 3e-11
Identities = 54/203 (26%), Positives = 97/203 (47%), Gaps = 31/203 (15%)
Query: 761 ELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERRLAEQ--RARIQQEYEEEQ 818
E++ EL K EE+++ EE ERE + EE+EER+ E+ ++++E EE++
Sbjct: 2229 EMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKK 2288
Query: 819 EKKREKEEEQRLKNEEHIRLAEE--RQKEAERKKKEEEEKYNLQLQHYCERDNLIGEETK 876
+KK+EK++E+ + EE EE ++E E EEEE+ + L+ +R+ I ++ K
Sbjct: 2289 KKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEK 2348
Query: 877 HMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIH-------------------ESSMSR 917
+ LQ + L+ V SI+R H +++
Sbjct: 2349 QFK--------LQEQRRKSLRGRERVLSILRGVPHGKGRAIRLGVLKSPLKKLMSTALEM 2400
Query: 918 AQSPPVPARKNQLRAEEEKKNVI 940
+ PVP + Q+ E++K V+
Sbjct: 2401 KEKTPVPVPEKQISWEDKKATVV 2423
Score = 58.5 bits (140), Expect = 4e-08
Identities = 60/286 (20%), Positives = 124/286 (43%), Gaps = 28/286 (9%)
Query: 600 GQNELKITSDQVINSGLIFEDKPKPSKQSLQSYQEALQQQIREREERRKKEREEK----E 655
GQ +L S ++I +P + L++ Q+ + + + +E K + ++ +
Sbjct: 2048 GQRKLAKASRKLIKKRESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVK 2107
Query: 656 EYEAKLEAEMRTYNPWGKGGGGAPLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRA 715
E +E W + + L D ++ R+ N R +
Sbjct: 2108 ERRLSIEQSKLDIKEWD-------FSEKRSELTKDEKKLARKQ-RKLANKMRRMINKEEK 2159
Query: 716 VVSLDPNLATSNAENLEDAANKSSGHMQTQSSPFARGN-------VFGEPPTELQIKQQE 768
+ + LA ++E + D + G + + PF + G+ P E Q +
Sbjct: 2160 MTEEESKLARKHSEVILDD-EEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVD 2218
Query: 769 LYKNFLRFQIEEKKQREEAERERLRIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQ 828
++ F E + +E E++ +EE+EER E+R + EEE+ K+ E+ EE+
Sbjct: 2219 EVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEK 2278
Query: 829 RLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEE 874
+++ EE E+++K+ E+KK+E +EK + + E++ ++ EE
Sbjct: 2279 QVEKEEE----EKKKKKKEKKKEEVQEKEEV----FEEKEEIMSEE 2316
Score = 52.8 bits (125), Expect = 2e-06
Identities = 82/353 (23%), Positives = 151/353 (42%), Gaps = 44/353 (12%)
Query: 625 SKQSLQSYQEALQQQIREREERRKKEREEKEEYEAKLEAEMRTYNPWGKGGGGAPLRDAK 684
SK Q Y++ + + EE +E EEKE+ + + ++ + W + + A+
Sbjct: 1531 SKSKEQQYKDEEEVTL---EEEVSREGEEKEQQVTEEQRHIQEEHKWAR----IHRKRAR 1583
Query: 685 GNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLED---AANKSSGH 741
+ Q + + +++R + + LA + + +D A
Sbjct: 1584 A------EKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKF 1637
Query: 742 MQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREE----AERERLRIAEE 797
Q + + RG + +L K+++L K + + EE+K ++ AE + + +A++
Sbjct: 1638 AQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNI-LAQK 1696
Query: 798 KEERRLAEQRARIQQ-EYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEK 856
EE EQ Q+ E +E E+ EE K EE L +E K E KKK EE+
Sbjct: 1697 VEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEE---LNQEEGKLVEEKKKLAEEE 1753
Query: 857 YNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSII---RSFIHES 913
L Q R+ L EETK + Q ++ + K+A ++ P + + R + E
Sbjct: 1754 EALAWQ----REKLSEEETK-LAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEK 1808
Query: 914 SMSRAQSPPVPARKNQLRAEEE--KKNVIM----ELSEMRKQLRSEERRLQER 960
M AQ R+ + + EE K +I+ L++ +K L E+ +L +R
Sbjct: 1809 KMKLAQK-----RERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQR 1856
Score = 49.7 bits (117), Expect = 2e-05
Identities = 51/255 (20%), Positives = 111/255 (43%), Gaps = 29/255 (11%)
Query: 757 EPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERRLAEQRARIQQEYEE 816
E E + K+Q++ + Q E K R +R R +EER+LA++ ++ QE +
Sbjct: 1549 EVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQ 1608
Query: 817 EQEKKRE---------KEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCER 867
+++R+ +++ + + E EE + K +E EK + + ++
Sbjct: 1609 LAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKK 1668
Query: 868 DNLIGEETKHMRQPSPIVPALQNKIASKL----QRPPSVDSIIRSFIHESSMSRAQSPPV 923
+ E + + + + ++N +A K+ QR ++D + E +
Sbjct: 1669 WEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEEL 1728
Query: 924 PARKNQLRAE-----EEKKNVIMELSEMRKQLRSEERRLQERLLHMDSDDEIPIRKKERN 978
++ +L E EEKK +L+E + L + +L E + ++E+ I++KE+
Sbjct: 1729 SWKEEELNQEEGKLVEEKK----KLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEK- 1783
Query: 979 PMDIFDMARHRLQAP 993
+A+H+ + P
Sbjct: 1784 ------LAQHKEKMP 1792
Score = 48.1 bits (113), Expect = 5e-05
Identities = 57/245 (23%), Positives = 114/245 (46%), Gaps = 38/245 (15%)
Query: 767 QELYKNFLRFQIEEKKQREEAE----RERLRIAEEKEERRLAEQ-------------RAR 809
+++++N L + +E++ ++E E E R EEKE++ EQ R R
Sbjct: 1522 KQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKR 1581
Query: 810 IQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEA---------ERKKKEEEEKYNLQ 860
+ E + QE+++ +EE++L EE +LA+E +K A +R+ + E K+ +
Sbjct: 1582 ARAEKKRAQEERKLAQEEEKLAQEER-QLAQEERKLAQAYVKITQDDREMAQAEGKFAQK 1640
Query: 861 LQHYCERDNLIGEETKHMRQPS-------PIVPALQNKIASKLQRPPSVDSIIRSFIHES 913
+ +R + +E + + Q V + K+A K + V +I+ + E
Sbjct: 1641 EETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEEL 1700
Query: 914 SMSRAQSPPVPARKNQLRAE-EEKKNVIMELSEMRKQLRSEERRLQERLLHMDSDDEIPI 972
R Q+ + ++ +L E EE + + ELS ++L EE +L E + ++E
Sbjct: 1701 P-QREQN--LDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALA 1757
Query: 973 RKKER 977
++E+
Sbjct: 1758 WQREK 1762
Score = 47.0 bits (110), Expect = 1e-04
Identities = 50/195 (25%), Positives = 84/195 (43%), Gaps = 55/195 (28%)
Query: 779 EEKKQREEAERERLRIAEEK---EERRLAEQRARIQQEYEEEQEKK-REKEEEQRLKNEE 834
EE ++R E E+L A EK EE L E + +E+++ E K +EQ+ K+EE
Sbjct: 1483 EEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEE 1542
Query: 835 HIRLAEERQKEAERKKKE-EEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIA 893
+ L EE +E E K+++ EE+ ++Q +H R
Sbjct: 1543 EVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWAR-------------------------- 1576
Query: 894 SKLQRPPSVDSIIRSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLRSE 953
IH RA++ A++ + A+EE+K L++ +QL E
Sbjct: 1577 ----------------IHR---KRARAEKKRAQEERKLAQEEEK-----LAQEERQLAQE 1612
Query: 954 ERRLQERLLHMDSDD 968
ER+L + + + DD
Sbjct: 1613 ERKLAQAYVKITQDD 1627
Score = 43.5 bits (101), Expect = 0.001
Identities = 57/270 (21%), Positives = 113/270 (41%), Gaps = 44/270 (16%)
Query: 753 NVFGEPPTELQIKQQEL--YKNFLRFQIEEKK--------QREEAERERLRIAEEKEERR 802
N+ + EL ++Q L + L ++EE + + EE +E ++ EEK++
Sbjct: 1691 NILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLA 1750
Query: 803 LAEQRARIQQEYEEEQEKKREKEEEQRLKN------------EEHIRLAEERQKEAERKK 850
E+ Q+E E+E K +EEE ++ EE RL +R++ E+K
Sbjct: 1751 EEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKM 1810
Query: 851 K--EEEEKYNLQLQHYC-------ERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPS 901
K ++ E++ ++ ++ NL E+ ++ + +N + +K + S
Sbjct: 1811 KLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHS 1870
Query: 902 VDSIIR---------SFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLRS 952
+++ + + Q +K + AE EKK V +E S +KQ
Sbjct: 1871 KKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQ--- 1927
Query: 953 EERRLQERLLHMDSDDEIPIRKKERNPMDI 982
E+ QE++ + +K+ R +DI
Sbjct: 1928 -EKLAQEKMKLALEKAMVQGKKRLRGELDI 1956
Score = 41.6 bits (96), Expect = 0.005
Identities = 102/535 (19%), Positives = 224/535 (41%), Gaps = 67/535 (12%)
Query: 599 VGQNELKITSDQVINSGLIFEDKPKPS--KQSLQSYQEALQQQIREREERRKKEREEKEE 656
+ + E K+ ++ L+ ++K K + K+ + +E L ++ + E++ K +++E
Sbjct: 1763 LSEEETKLAQEEE----LLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRER 1818
Query: 657 YEAKLEA----EMRTYNPWGKGGGGAPLRDAKGNLITDLNRMHRQNIDAYHNPDARTYED 712
+ +E +M Y L K NL + ++ ++ + +N + T+
Sbjct: 1819 WINSMEELTKNKMILYQKKN-------LAQEKKNLAQEKEKLAQRKENLLYNKERLTHS- 1870
Query: 713 KRAVVSLDPNLATSN---AENLEDAANKSSGHMQTQSSPFARGNVFGEPPTELQIKQQEL 769
K+ +V + L N A+ E + ++ + + L KQ++L
Sbjct: 1871 KKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKL 1930
Query: 770 YKNFLRFQIEEKK-QREEAERERLRIAEEKEE-------RRLAEQRARIQQEYE-----E 816
+ ++ +E+ Q ++ R L IA KEE +RLAE++ R+ + E E
Sbjct: 1931 AQEKMKLALEKAMVQGKKRLRGELDIA--KEEKALNLEMKRLAEEKMRLVEGKETLSKGE 1988
Query: 817 EQEKKREKEE--------EQRLKNEEHIRLAEER---QKEAERKKKEEEEKYNLQLQHYC 865
E R+++ E++L EE I L E+R +E+E K + E + + +
Sbjct: 1989 TPETSRQRKMTQVEQELFERKLSLEEKILLHEDRILAMEESEIAKGKLE--FTRGQRIFV 2046
Query: 866 ERDNLIGEETKHM---RQPSPIVPALQNKIASKLQRPPSVD-SIIRSFIHESSMSRAQSP 921
+ + + ++ + R+ PA NKI LQ+ + + + I + M RA
Sbjct: 2047 QGQRKLAKASRKLIKKRESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRA--- 2103
Query: 922 PVPARKNQLRAEEEKKNV-IMELSEMRKQLRSEERRLQERLLHMDSDDEIPIRKKERNPM 980
+ ++ +L E+ K ++ + SE R +L +E++L + + + I K+E+
Sbjct: 2104 -LFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTE 2162
Query: 981 DIFDMARHRLQAPVRRQSPKGLDAATFQNVHDF-----NELKDRDSETRVDLKF-MYLDP 1034
+ +AR + + + G++ + V F + K+ + KF +D
Sbjct: 2163 EESKLARKHSEVILDDEEEGGIEE---EEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDE 2219
Query: 1035 PRDHHTLEIQQQALLREQQKRLNRIKMQEGAKVDLDAIPSAKVREQRMPRDDTSD 1089
+ ++LL E +K+ + +E + + + +VRE+ R + +
Sbjct: 2220 VESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEE 2274
Score = 32.3 bits (72), Expect = 2.9
Identities = 44/185 (23%), Positives = 78/185 (42%), Gaps = 19/185 (10%)
Query: 117 ERKKHKLKEELRQDY-RRYLTQGITQGKRKKNFLSTSET--DPSTLGVSLPIGERLSAKE 173
+R+ K KE R D + + + + + +++F E+ D SL E +E
Sbjct: 2194 KRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREE 2253
Query: 174 RLKLERNKEYNQFLRGKEESSEKFRQVEKSTEPKSQRNKKPIGQVKPDLTSQIQTSCENS 233
+ E + + KEE + +QVEK E K ++ K + K + + + E
Sbjct: 2254 EEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKK----EKKKEEVQEKEEVFEEK 2309
Query: 234 EGPRKDVLTPSEAYEELLNQRRLEEDRYRQLDDEIELRNRRIIKKANEEVGISNLKHQRF 293
E + T S + EE EE+ L++E++ R + I+KK + L+ QR
Sbjct: 2310 EEIMSEEETESLSDEE-------EEEESCSLEEEVD-REKEILKKEKQ----FKLQEQRR 2357
Query: 294 ASKAG 298
S G
Sbjct: 2358 KSLRG 2362
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 68.6 bits (166), Expect = 4e-11
Identities = 62/263 (23%), Positives = 122/263 (46%), Gaps = 16/263 (6%)
Query: 720 DPNLATSNAENLEDAANKSSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIE 779
+P S E L+D N H++ + R + +++ ++ R Q E
Sbjct: 151 EPPAGPSKVEQLQDETN----HLRKELESVGR-------QLQAEVENNQMLSLLNRRQEE 199
Query: 780 EKKQREEAERERLRIAEEKEERRLA-EQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRL 838
+++EE RE+ E+EER E+R R Q+E EQE++ ++EE+ ++EE +
Sbjct: 200 RLREQEERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQEERLREHEERLCE 259
Query: 839 AEERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQR 898
EER E E + +E+EE+ + Q + CE++ + E+ + + + + + ++ + +R
Sbjct: 260 QEERLCEQEERLREQEERLHEQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEER 319
Query: 899 PPSVDSIIRSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIME--LSEMRKQLRSEERR 956
+ + R + + R EE+++ + E L E+ + L E R
Sbjct: 320 LREQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLEEVEELLEQERLR 379
Query: 957 LQ-ERLLHMDSDDEIP-IRKKER 977
Q ERL ++ E+ +R+ ER
Sbjct: 380 QQDERLWQQETLQELERLRELER 402
Score = 45.8 bits (107), Expect = 3e-04
Identities = 83/401 (20%), Positives = 148/401 (36%), Gaps = 42/401 (10%)
Query: 540 PPLATN--YRTPYDDAYYFYGSRNTFDPSLAYYGSGMMGVQPAAYVSAPVTHQLAQPVVN 597
P AT+ Y +P D A YG +L S + A S+ + QL + + +
Sbjct: 55 PDTATSGGYHSPGDSATGIYGEGRASSTTLEDLESQYQELAVALDSSSAIISQLTENINS 114
Query: 598 TV--GQNELKITSDQVINSGLIFEDKPKPSKQSLQSYQEALQQQIREREERRKKEREEKE 655
V + E K V G + + L A ++ + ++ R+E E
Sbjct: 115 LVRTSKEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELE 174
Query: 656 EYEAKLEAEMRTYNPWGKGGGGAPLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRA 715
+L+AE+ L + + + R+ + + R E +
Sbjct: 175 SVGRQLQAEVENNQMLSL------LNRRQEERLREQEERLREQEERLREQEERLCEQEER 228
Query: 716 VVSLDPNLATSNAENLEDAANKSSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLR 775
+ + L E L + + H + R E L+ +++ L++ R
Sbjct: 229 LREQEERLREQE-ERLCEQEERLREHEERLCEQEER---LCEQEERLREQEERLHEQEER 284
Query: 776 FQIEEKKQREEAER-----ERLRIAEEK---EERRLAEQRARIQQ--------------- 812
+E++ RE+ ER ERLR EE+ +E RL EQ R+ +
Sbjct: 285 LCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEKLPGQERLLEEVE 344
Query: 813 ---EYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCERDN 869
E E QE++ E +RL E L +ER ++ + + ++E L+ ER
Sbjct: 345 KLLEQERRQEEQERLLERERLLEEVEELLEQERLRQQDERLWQQETLQELERLRELERML 404
Query: 870 LIGEETKHMRQPSPI--VPALQNKIASKLQRPPSVDSIIRS 908
+G E + ++ P L N+ S LQ V + +S
Sbjct: 405 ELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELKKS 445
Score = 32.3 bits (72), Expect = 2.9
Identities = 61/301 (20%), Positives = 119/301 (39%), Gaps = 26/301 (8%)
Query: 78 ENSKILISMAKENIPPNSQQTRGSLGIDYGLSLPLGEDYERKKHKLKEELRQDYRRYLTQ 137
++S +IS ENI + ++ + L LG + K++ E L + ++
Sbjct: 99 DSSSAIISQLTENINSLVRTSKEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSK 158
Query: 138 GITQGKRKKNFLSTS-ETDPSTLGVSLPIGERLSAKERLKLERNKEYNQFLRGKEE---- 192
+ Q + + N L E+ L + + LS R + ER +E + LR +EE
Sbjct: 159 -VEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLRE 217
Query: 193 -------SSEKFRQVEKSTEPKSQR---NKKPIGQVKPDLTSQIQTSCENSEGPRKDVLT 242
E+ R+ E+ + +R ++ + + + L Q + CE E R+
Sbjct: 218 QEERLCEQEERLREQEERLREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEER 277
Query: 243 PSEAYEELLNQ-RRLEEDRYRQLDDEIELRNRRIIKKANEEVGISNLKHQRFASKAGIPD 301
E E L Q RL E R + E LR + ++ E+ + +R + +P
Sbjct: 278 LHEQEERLCEQEERLREQEERLCEQEERLREQE--ERLCEQEERLREQEERLCEQEKLPG 335
Query: 302 RRFHRFNEDRVFDRRYHRPDQD-----PEVSEEMDERFRYE--SDFDRRLSRVYTNDRMH 354
+ +++ ++ + +Q+ + EE++E E D RL + T +
Sbjct: 336 QERLLEEVEKLLEQERRQEEQERLLERERLLEEVEELLEQERLRQQDERLWQQETLQELE 395
Query: 355 R 355
R
Sbjct: 396 R 396
>gi|4506467 radixin [Homo sapiens]
Length = 583
Score = 68.6 bits (166), Expect = 4e-11
Identities = 71/255 (27%), Positives = 113/255 (44%), Gaps = 59/255 (23%)
Query: 763 QIKQQELYKNFLRFQIE-EKKQREEAERERLRIAEEKEE-----RRLAEQRARIQQEYEE 816
Q ++++ K R Q+E EKK+RE AE+E+ RI EKEE +++ EQ + Q+E EE
Sbjct: 308 QAREEKHQKQLERAQLENEKKKREIAEKEKERIEREKEELMERLKQIEEQTIKAQKELEE 367
Query: 817 E--------QEKKREKEEEQRL----------------------KNEEHI--RLAEERQK 844
+ QE+KR KEE +RL KN+E + LAE K
Sbjct: 368 QTRKALELDQERKRAKEEAERLEKERRAAEEAKSAIAKQAADQMKNQEQLAAELAEFTAK 427
Query: 845 EA---ERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQ----------PSPIVPALQNK 891
A E KKK+EEE Q + + +++L E+TK + P P++P +N+
Sbjct: 428 IALLEEAKKKKEEEATEWQHKAFAAQEDL--EKTKEELKTVMSAPPPPPPPPVIPPTENE 485
Query: 892 IASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLR 951
+ + +E M+ R + + E K + LS Q R
Sbjct: 486 HDEHDENNAEASA---ELSNEGVMNHRSE---EERVTETQKNERVKKQLQALSSELAQAR 539
Query: 952 SEERRLQERLLHMDS 966
E ++ Q +LH ++
Sbjct: 540 DETKKTQNDVLHAEN 554
Score = 37.4 bits (85), Expect = 0.091
Identities = 20/73 (27%), Positives = 46/73 (63%), Gaps = 4/73 (5%)
Query: 786 EAERERLRIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNE--EHIRLAEERQ 843
E ++ + + EEK +++L +RA+++ E ++ + ++EKE +R K E E ++ EE+
Sbjct: 301 EVQQMKAQAREEKHQKQL--ERAQLENEKKKREIAEKEKERIEREKEELMERLKQIEEQT 358
Query: 844 KEAERKKKEEEEK 856
+A+++ +E+ K
Sbjct: 359 IKAQKELEEQTRK 371
Score = 32.7 bits (73), Expect = 2.2
Identities = 18/54 (33%), Positives = 31/54 (57%), Gaps = 1/54 (1%)
Query: 801 RRLAEQRARIQQEYEEEQEKKREKE-EEQRLKNEEHIRLAEERQKEAERKKKEE 853
RR +QQ + +E+K +K+ E +L+NE+ R E++KE ++KEE
Sbjct: 293 RRRKPDTIEVQQMKAQAREEKHQKQLERAQLENEKKKREIAEKEKERIEREKEE 346
Score = 30.8 bits (68), Expect = 8.5
Identities = 35/158 (22%), Positives = 64/158 (40%), Gaps = 18/158 (11%)
Query: 156 PSTLGVSLPIGERLSAKERLKLER-------------NKEYNQFLRGKEESSEKFRQVEK 202
P T+ V + K + +LER KE + R KEE E+ +Q+E+
Sbjct: 297 PDTIEVQQMKAQAREEKHQKQLERAQLENEKKKREIAEKEKERIEREKEELMERLKQIEE 356
Query: 203 STEPKSQRNKKPIGQVKPDLTSQIQTSCENSEGPRKDVLTPSEAYEELLNQRRLEEDRYR 262
T K+Q+ + + +L + + + E +E K+ EA + Q +
Sbjct: 357 QT-IKAQKELEEQTRKALELDQERKRAKEEAERLEKERRAAEEAKSAIAKQAADQMKNQE 415
Query: 263 QLDDEIELRNRRII----KKANEEVGISNLKHQRFASK 296
QL E+ +I K +E + +H+ FA++
Sbjct: 416 QLAAELAEFTAKIALLEEAKKKKEEEATEWQHKAFAAQ 453
>gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo
sapiens]
Length = 1268
Score = 68.2 bits (165), Expect = 5e-11
Identities = 44/149 (29%), Positives = 78/149 (52%), Gaps = 23/149 (15%)
Query: 753 NVFGEPPTELQIK-QQELYKNFLRFQIEEKKQREEAERERL------------------- 792
N GEP + L + + L ++FLR Q+ K++ E R++L
Sbjct: 333 NDSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQ 392
Query: 793 -RIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKK 851
RI E+KE+RR E++ R ++E ++QE+++ + E++++ EE R AE Q+ ++ +
Sbjct: 393 KRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYKRKQLE 452
Query: 852 EEEEKYNLQLQHYCERDNLIGEETKHMRQ 880
E+ + LQ Q ERD L+ +H RQ
Sbjct: 453 EQRQAERLQRQLKQERDYLV--SLQHQRQ 479
Score = 52.4 bits (124), Expect = 3e-06
Identities = 74/350 (21%), Positives = 138/350 (39%), Gaps = 58/350 (16%)
Query: 612 INSGLIFEDKPKPSKQSLQSY--------QEALQQQIREREERRKKEREEKEE--YEAKL 661
I S L+ +P+ + L + + ++ Q+++ +R KK+R EK+E YE
Sbjct: 266 IESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRIQLKDHIDRTKKKRGEKDETEYEYSG 325
Query: 662 EAEMRTYNPWGKGGGGAPLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDP 721
E N G+ L + L D R+ N
Sbjct: 326 SEEEEEENDSGEPSSILNL-PGESTLRRDFLRLQLAN----------------------- 361
Query: 722 NLATSNAENLEDAANKSSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEK 781
+ +A + Q + + + + E ++ +Q+E + Q EK
Sbjct: 362 -------KERSEALRRQQLEQQQRENEEHKRQLLAERQKRIE-EQKEQRRRLEEQQRREK 413
Query: 782 KQREEAERERLRIAEEKEERRLAEQRARIQQEYEEEQ-EKKREKEEEQRLKNEEHIRLAE 840
+ R++ ERE+ R EE+ R +RA +QEY+ +Q E++R+ E QR +E L
Sbjct: 414 ELRKQQEREQRRHYEEQMRREEERRRAEHEQEYKRKQLEEQRQAERLQRQLKQERDYLVS 473
Query: 841 ERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEETKHM---RQPSPIVPALQN------K 891
+ + E++ E++ Y+ + +E H+ + P + A Q+ K
Sbjct: 474 LQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEIPHLVAVKSQGPALTASQSVHEQPTK 533
Query: 892 IASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPA------RKNQLRAEEE 935
S Q +V S ++S +++PP+P R + LR EE+
Sbjct: 534 GLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSSWLRQEED 583
Score = 42.4 bits (98), Expect = 0.003
Identities = 63/266 (23%), Positives = 107/266 (40%), Gaps = 89/266 (33%)
Query: 743 QTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERR 802
Q PF R + P E Q++ Q K+ + +++ +++E E E EE+EE
Sbjct: 282 QLMKHPFIR-----DQPNERQVRIQ--LKDHIDRTKKKRGEKDETEYEYSGSEEEEEEND 334
Query: 803 LAEQRA---------------RIQQEYEEEQEK-KREKEEEQRLKNEEHIR-LAEERQKE 845
E + R+Q +E E +R++ E+Q+ +NEEH R L ERQK
Sbjct: 335 SGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKR 394
Query: 846 AERKKK-----EEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPP 900
E +K+ EE+++ +L+ ER E+ +H +
Sbjct: 395 IEEQKEQRRRLEEQQRREKELRKQQER-----EQRRHYEE-------------------- 429
Query: 901 SVDSIIRSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLRSEERRLQER 960
Q+R EEE++ E RKQL EE+R ER
Sbjct: 430 ----------------------------QMRREEERRRAEHEQEYKRKQL--EEQRQAER 459
Query: 961 L---LHMDSDDEIPI--RKKERNPMD 981
L L + D + + +++E+ P++
Sbjct: 460 LQRQLKQERDYLVSLQHQRQEQRPVE 485
>gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo
sapiens]
Length = 1276
Score = 68.2 bits (165), Expect = 5e-11
Identities = 44/149 (29%), Positives = 78/149 (52%), Gaps = 23/149 (15%)
Query: 753 NVFGEPPTELQIK-QQELYKNFLRFQIEEKKQREEAERERL------------------- 792
N GEP + L + + L ++FLR Q+ K++ E R++L
Sbjct: 333 NDSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQ 392
Query: 793 -RIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKK 851
RI E+KE+RR E++ R ++E ++QE+++ + E++++ EE R AE Q+ ++ +
Sbjct: 393 KRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYKRKQLE 452
Query: 852 EEEEKYNLQLQHYCERDNLIGEETKHMRQ 880
E+ + LQ Q ERD L+ +H RQ
Sbjct: 453 EQRQAERLQRQLKQERDYLV--SLQHQRQ 479
Score = 52.4 bits (124), Expect = 3e-06
Identities = 74/350 (21%), Positives = 138/350 (39%), Gaps = 58/350 (16%)
Query: 612 INSGLIFEDKPKPSKQSLQSY--------QEALQQQIREREERRKKEREEKEE--YEAKL 661
I S L+ +P+ + L + + ++ Q+++ +R KK+R EK+E YE
Sbjct: 266 IESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRIQLKDHIDRTKKKRGEKDETEYEYSG 325
Query: 662 EAEMRTYNPWGKGGGGAPLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDP 721
E N G+ L + L D R+ N
Sbjct: 326 SEEEEEENDSGEPSSILNL-PGESTLRRDFLRLQLAN----------------------- 361
Query: 722 NLATSNAENLEDAANKSSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEK 781
+ +A + Q + + + + E ++ +Q+E + Q EK
Sbjct: 362 -------KERSEALRRQQLEQQQRENEEHKRQLLAERQKRIE-EQKEQRRRLEEQQRREK 413
Query: 782 KQREEAERERLRIAEEKEERRLAEQRARIQQEYEEEQ-EKKREKEEEQRLKNEEHIRLAE 840
+ R++ ERE+ R EE+ R +RA +QEY+ +Q E++R+ E QR +E L
Sbjct: 414 ELRKQQEREQRRHYEEQMRREEERRRAEHEQEYKRKQLEEQRQAERLQRQLKQERDYLVS 473
Query: 841 ERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEETKHM---RQPSPIVPALQN------K 891
+ + E++ E++ Y+ + +E H+ + P + A Q+ K
Sbjct: 474 LQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEIPHLVAVKSQGPALTASQSVHEQPTK 533
Query: 892 IASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPA------RKNQLRAEEE 935
S Q +V S ++S +++PP+P R + LR EE+
Sbjct: 534 GLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSSWLRQEED 583
Score = 42.4 bits (98), Expect = 0.003
Identities = 63/266 (23%), Positives = 107/266 (40%), Gaps = 89/266 (33%)
Query: 743 QTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERR 802
Q PF R + P E Q++ Q K+ + +++ +++E E E EE+EE
Sbjct: 282 QLMKHPFIR-----DQPNERQVRIQ--LKDHIDRTKKKRGEKDETEYEYSGSEEEEEEND 334
Query: 803 LAEQRA---------------RIQQEYEEEQEK-KREKEEEQRLKNEEHIR-LAEERQKE 845
E + R+Q +E E +R++ E+Q+ +NEEH R L ERQK
Sbjct: 335 SGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKR 394
Query: 846 AERKKK-----EEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPP 900
E +K+ EE+++ +L+ ER E+ +H +
Sbjct: 395 IEEQKEQRRRLEEQQRREKELRKQQER-----EQRRHYEE-------------------- 429
Query: 901 SVDSIIRSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLRSEERRLQER 960
Q+R EEE++ E RKQL EE+R ER
Sbjct: 430 ----------------------------QMRREEERRRAEHEQEYKRKQL--EEQRQAER 459
Query: 961 L---LHMDSDDEIPI--RKKERNPMD 981
L L + D + + +++E+ P++
Sbjct: 460 LQRQLKQERDYLVSLQHQRQEQRPVE 485
>gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo
sapiens]
Length = 1352
Score = 67.8 bits (164), Expect = 6e-11
Identities = 64/292 (21%), Positives = 123/292 (42%), Gaps = 43/292 (14%)
Query: 753 NVFGEPPTELQIK-QQELYKNFLRFQIEEKKQREEAERERL------------------- 792
N GEP + L + + L ++FLR Q+ K++ E R++L
Sbjct: 333 NDSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQ 392
Query: 793 -RIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKK 851
RI E+KE+RR E++ R ++E ++QE+++ + E++++ EE R AE Q+ R+ +
Sbjct: 393 KRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYIRRQLE 452
Query: 852 EEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIH 911
EE+ + + Q L+ E + + + + A +LQR + R ++
Sbjct: 453 EEQRQLEILQQQLLHEQALLLEYKRKQLE--------EQRQAERLQRQLKQE---RDYLV 501
Query: 912 ESSMSRAQSPPVPARK----NQLRAEEEKKNVIMELSEMRKQLRSEERRLQERLLHMDSD 967
R + PV + + + EK E+ E + R + ++ + SD
Sbjct: 502 SLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEVEERSRLNRQSSPAMPHKVANRISD 561
Query: 968 DEIPIRKKERNPMDIFDMARHRLQAPVRRQSP-------KGLDAATFQNVHD 1012
+P R + + + + PV Q P +G Q+VH+
Sbjct: 562 PNLPPRSESFSISGVQPARTPPMLRPVDPQIPHLVAVKSQGPALTASQSVHE 613
Score = 46.6 bits (109), Expect = 1e-04
Identities = 59/246 (23%), Positives = 99/246 (40%), Gaps = 85/246 (34%)
Query: 743 QTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERR 802
Q PF R + P E Q++ Q K+ + +++ +++E E E EE+EE
Sbjct: 282 QLMKHPFIR-----DQPNERQVRIQ--LKDHIDRTKKKRGEKDETEYEYSGSEEEEEEND 334
Query: 803 LAEQRA---------------RIQQEYEEEQEK-KREKEEEQRLKNEEHIR-LAEERQKE 845
E + R+Q +E E +R++ E+Q+ +NEEH R L ERQK
Sbjct: 335 SGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKR 394
Query: 846 AE-----RKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPP 900
E R++ EE+++ +L+ ER E+ +H +
Sbjct: 395 IEEQKEQRRRLEEQQRREKELRKQQER-----EQRRHYEE-------------------- 429
Query: 901 SVDSIIRSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLRSEERR---L 957
Q+R EEE++ E +R+QL E+R+ L
Sbjct: 430 ----------------------------QMRREEERRRAEHEQEYIRRQLEEEQRQLEIL 461
Query: 958 QERLLH 963
Q++LLH
Sbjct: 462 QQQLLH 467
Score = 32.3 bits (72), Expect = 2.9
Identities = 13/48 (27%), Positives = 29/48 (60%)
Query: 617 IFEDKPKPSKQSLQSYQEALQQQIREREERRKKEREEKEEYEAKLEAE 664
+ ++ K ++ + + +QQ RE+E R+++ERE++ YE ++ E
Sbjct: 387 LLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRRE 434
>gi|55741807 TRAF2 and NCK interacting kinase isoform 1 [Homo sapiens]
Length = 1360
Score = 67.8 bits (164), Expect = 6e-11
Identities = 64/292 (21%), Positives = 123/292 (42%), Gaps = 43/292 (14%)
Query: 753 NVFGEPPTELQIK-QQELYKNFLRFQIEEKKQREEAERERL------------------- 792
N GEP + L + + L ++FLR Q+ K++ E R++L
Sbjct: 333 NDSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQ 392
Query: 793 -RIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKK 851
RI E+KE+RR E++ R ++E ++QE+++ + E++++ EE R AE Q+ R+ +
Sbjct: 393 KRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYIRRQLE 452
Query: 852 EEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIH 911
EE+ + + Q L+ E + + + + A +LQR + R ++
Sbjct: 453 EEQRQLEILQQQLLHEQALLLEYKRKQLE--------EQRQAERLQRQLKQE---RDYLV 501
Query: 912 ESSMSRAQSPPVPARK----NQLRAEEEKKNVIMELSEMRKQLRSEERRLQERLLHMDSD 967
R + PV + + + EK E+ E + R + ++ + SD
Sbjct: 502 SLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEVEERSRLNRQSSPAMPHKVANRISD 561
Query: 968 DEIPIRKKERNPMDIFDMARHRLQAPVRRQSP-------KGLDAATFQNVHD 1012
+P R + + + + PV Q P +G Q+VH+
Sbjct: 562 PNLPPRSESFSISGVQPARTPPMLRPVDPQIPHLVAVKSQGPALTASQSVHE 613
Score = 46.6 bits (109), Expect = 1e-04
Identities = 59/246 (23%), Positives = 99/246 (40%), Gaps = 85/246 (34%)
Query: 743 QTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERR 802
Q PF R + P E Q++ Q K+ + +++ +++E E E EE+EE
Sbjct: 282 QLMKHPFIR-----DQPNERQVRIQ--LKDHIDRTKKKRGEKDETEYEYSGSEEEEEEND 334
Query: 803 LAEQRA---------------RIQQEYEEEQEK-KREKEEEQRLKNEEHIR-LAEERQKE 845
E + R+Q +E E +R++ E+Q+ +NEEH R L ERQK
Sbjct: 335 SGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKR 394
Query: 846 AE-----RKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPP 900
E R++ EE+++ +L+ ER E+ +H +
Sbjct: 395 IEEQKEQRRRLEEQQRREKELRKQQER-----EQRRHYEE-------------------- 429
Query: 901 SVDSIIRSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLRSEERR---L 957
Q+R EEE++ E +R+QL E+R+ L
Sbjct: 430 ----------------------------QMRREEERRRAEHEQEYIRRQLEEEQRQLEIL 461
Query: 958 QERLLH 963
Q++LLH
Sbjct: 462 QQQLLH 467
Score = 32.3 bits (72), Expect = 2.9
Identities = 13/48 (27%), Positives = 29/48 (60%)
Query: 617 IFEDKPKPSKQSLQSYQEALQQQIREREERRKKEREEKEEYEAKLEAE 664
+ ++ K ++ + + +QQ RE+E R+++ERE++ YE ++ E
Sbjct: 387 LLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRRE 434
>gi|62244004 modulator of estrogen induced transcription isoform b
[Homo sapiens]
Length = 1016
Score = 67.4 bits (163), Expect = 8e-11
Identities = 57/169 (33%), Positives = 91/169 (53%), Gaps = 22/169 (13%)
Query: 763 QIKQQELYKNFLRFQI----------EEKKQREEAERERLRIAEEKEER-RLAEQRARIQ 811
++K+Q L ++ +RF+ E +RE ERER+RI E+EER RL +R R++
Sbjct: 591 KMKEQRLREHLVRFERLRRAMELRRRREIAERERRERERIRIIREREERERLQRERERLE 650
Query: 812 QEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCERDNLI 871
E Q+ +RE+ E +RL+ E IR+ +ER+KEAER +E EE Q Q E+
Sbjct: 651 IE---RQKLERERMERERLERER-IRIEQERRKEAERIAREREELRRQQQQLRYEQ---- 702
Query: 872 GEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQS 920
E+ +++P + + S+ + S+D+ R F H S SR Q+
Sbjct: 703 -EKRNSLKRPRDVDHRRDDPYWSE-NKKLSLDTDAR-FGHGSDYSRQQN 748
Score = 41.6 bits (96), Expect = 0.005
Identities = 38/144 (26%), Positives = 69/144 (47%), Gaps = 22/144 (15%)
Query: 780 EKKQREEAERERLRIAEEKEERRLAE-----QRARIQQEYEEEQE-KKREKEEEQRLK-- 831
+KK+ ++ R+ + E+ +E+RL E +R R E +E +RE+ E +R++
Sbjct: 574 DKKRDKDYRRKEILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAERERRERERIRII 633
Query: 832 --NEEHIRLAEERQK-EAERKKKE---------EEEKYNLQLQHYCERDNLIGEETKHMR 879
EE RL ER++ E ER+K E E E+ ++ + E + + E + R
Sbjct: 634 REREERERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIAREREELRR 693
Query: 880 QPSPIVPALQNKIASKLQRPPSVD 903
Q + + + + L+RP VD
Sbjct: 694 QQQQL--RYEQEKRNSLKRPRDVD 715
Score = 37.7 bits (86), Expect = 0.070
Identities = 99/499 (19%), Positives = 178/499 (35%), Gaps = 74/499 (14%)
Query: 751 RGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERRLAEQRARI 810
R + G+ + ++K K + E+ R +++ K + + ++ R
Sbjct: 429 RTELHGQLISVEKVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRS 488
Query: 811 QQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCERDNL 870
++ E+++ K +K E + KN+ A + E+ +K +E++ + H D
Sbjct: 489 SEKSEKKESKDTKKIEGKDEKNDNG---ASGQTSESIKKSEEKKRISSKSPGHMVILDQT 545
Query: 871 IGEETKHMRQPSPIVPALQNKI--ASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPARKN 928
G+ + R+ KI SK + S+D + R + P K
Sbjct: 546 KGDHCRPSRR------GRYEKIHGRSKEKERASLDK-----KRDKDYRRKEILPFEKMKE 594
Query: 929 QLRAEE----EKKNVIMELSEMRKQLRSEERRLQERLLHMDSDDEIPIRKKERNPMDIFD 984
Q E E+ MEL R+++ ERR +ER+ + +ER +
Sbjct: 595 QRLREHLVRFERLRRAMEL-RRRREIAERERRERERIRII----------REREERERLQ 643
Query: 985 MARHRLQAPVRRQSPKGLDAATFQNVHDFNELKDRDSETRVDLKFMYLDPPRDHHTLEIQ 1044
R RL+ ++ + ++ + E + R R+ R+ L Q
Sbjct: 644 RERERLEIERQKLERERMERERLERERIRIEQERRKEAERI---------AREREELRRQ 694
Query: 1045 QQALLREQQKRLNRIKMQEGAKVDLDAIPSAKVREQRMPRDDTSDFLKNSLLESDSAFIG 1104
QQ L EQ+KR N +K D+D R D + +N L D+
Sbjct: 695 QQQLRYEQEKR-NSLKRPR----DVD------------HRRDDPYWSENKKLSLDTDARF 737
Query: 1105 AYGETYPAIEDDV----------LPPPSQLPSARERRRNKWKG-LDIDSSRPNVAPDGLS 1153
+G Y ++ P S + S+ RR+++ G + +RP + S
Sbjct: 738 GHGSDYSRQQNRFNDFDHRERGRFPESSAVQSSSFERRDRFVGQSEGKKARPTARREDPS 797
Query: 1154 LKSISSVNVDELRVRNEERMRRLNEFHNKPINTD-DESSLV---DPDDIM--KHIGDDGS 1207
+ D R L E + + + DE V D DI +H + G
Sbjct: 798 FERYPKNFSDSRRNEPPPPRNELRESDRREVRGERDERRTVIIHDRPDITHPRHPREAGP 857
Query: 1208 NSVATEPWLRPGTSETLKR 1226
N W G+ T KR
Sbjct: 858 NPSRPTSWKSEGSMSTDKR 876
>gi|63176611 modulator of estrogen induced transcription isoform a
[Homo sapiens]
Length = 1034
Score = 67.4 bits (163), Expect = 8e-11
Identities = 57/169 (33%), Positives = 91/169 (53%), Gaps = 22/169 (13%)
Query: 763 QIKQQELYKNFLRFQI----------EEKKQREEAERERLRIAEEKEER-RLAEQRARIQ 811
++K+Q L ++ +RF+ E +RE ERER+RI E+EER RL +R R++
Sbjct: 609 KMKEQRLREHLVRFERLRRAMELRRRREIAERERRERERIRIIREREERERLQRERERLE 668
Query: 812 QEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCERDNLI 871
E Q+ +RE+ E +RL+ E IR+ +ER+KEAER +E EE Q Q E+
Sbjct: 669 IE---RQKLERERMERERLERER-IRIEQERRKEAERIAREREELRRQQQQLRYEQ---- 720
Query: 872 GEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQS 920
E+ +++P + + S+ + S+D+ R F H S SR Q+
Sbjct: 721 -EKRNSLKRPRDVDHRRDDPYWSE-NKKLSLDTDAR-FGHGSDYSRQQN 766
Score = 41.6 bits (96), Expect = 0.005
Identities = 38/144 (26%), Positives = 69/144 (47%), Gaps = 22/144 (15%)
Query: 780 EKKQREEAERERLRIAEEKEERRLAE-----QRARIQQEYEEEQE-KKREKEEEQRLK-- 831
+KK+ ++ R+ + E+ +E+RL E +R R E +E +RE+ E +R++
Sbjct: 592 DKKRDKDYRRKEILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAERERRERERIRII 651
Query: 832 --NEEHIRLAEERQK-EAERKKKE---------EEEKYNLQLQHYCERDNLIGEETKHMR 879
EE RL ER++ E ER+K E E E+ ++ + E + + E + R
Sbjct: 652 REREERERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIAREREELRR 711
Query: 880 QPSPIVPALQNKIASKLQRPPSVD 903
Q + + + + L+RP VD
Sbjct: 712 QQQQL--RYEQEKRNSLKRPRDVD 733
Score = 37.7 bits (86), Expect = 0.070
Identities = 99/499 (19%), Positives = 178/499 (35%), Gaps = 74/499 (14%)
Query: 751 RGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERRLAEQRARI 810
R + G+ + ++K K + E+ R +++ K + + ++ R
Sbjct: 447 RTELHGQLISVEKVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRS 506
Query: 811 QQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCERDNL 870
++ E+++ K +K E + KN+ A + E+ +K +E++ + H D
Sbjct: 507 SEKSEKKESKDTKKIEGKDEKNDNG---ASGQTSESIKKSEEKKRISSKSPGHMVILDQT 563
Query: 871 IGEETKHMRQPSPIVPALQNKI--ASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPARKN 928
G+ + R+ KI SK + S+D + R + P K
Sbjct: 564 KGDHCRPSRR------GRYEKIHGRSKEKERASLDK-----KRDKDYRRKEILPFEKMKE 612
Query: 929 QLRAEE----EKKNVIMELSEMRKQLRSEERRLQERLLHMDSDDEIPIRKKERNPMDIFD 984
Q E E+ MEL R+++ ERR +ER+ + +ER +
Sbjct: 613 QRLREHLVRFERLRRAMEL-RRRREIAERERRERERIRII----------REREERERLQ 661
Query: 985 MARHRLQAPVRRQSPKGLDAATFQNVHDFNELKDRDSETRVDLKFMYLDPPRDHHTLEIQ 1044
R RL+ ++ + ++ + E + R R+ R+ L Q
Sbjct: 662 RERERLEIERQKLERERMERERLERERIRIEQERRKEAERI---------AREREELRRQ 712
Query: 1045 QQALLREQQKRLNRIKMQEGAKVDLDAIPSAKVREQRMPRDDTSDFLKNSLLESDSAFIG 1104
QQ L EQ+KR N +K D+D R D + +N L D+
Sbjct: 713 QQQLRYEQEKR-NSLKRPR----DVD------------HRRDDPYWSENKKLSLDTDARF 755
Query: 1105 AYGETYPAIEDDV----------LPPPSQLPSARERRRNKWKG-LDIDSSRPNVAPDGLS 1153
+G Y ++ P S + S+ RR+++ G + +RP + S
Sbjct: 756 GHGSDYSRQQNRFNDFDHRERGRFPESSAVQSSSFERRDRFVGQSEGKKARPTARREDPS 815
Query: 1154 LKSISSVNVDELRVRNEERMRRLNEFHNKPINTD-DESSLV---DPDDIM--KHIGDDGS 1207
+ D R L E + + + DE V D DI +H + G
Sbjct: 816 FERYPKNFSDSRRNEPPPPRNELRESDRREVRGERDERRTVIIHDRPDITHPRHPREAGP 875
Query: 1208 NSVATEPWLRPGTSETLKR 1226
N W G+ T KR
Sbjct: 876 NPSRPTSWKSEGSMSTDKR 894
>gi|22035606 mitogen-activated protein kinase kinase kinase kinase 4
isoform 3 [Homo sapiens]
Length = 1212
Score = 67.0 bits (162), Expect = 1e-10
Identities = 49/145 (33%), Positives = 82/145 (56%), Gaps = 25/145 (17%)
Query: 756 GEPPTELQIK-QQELYKNFLRFQIEEKKQREEA-------ERERLRIAEEKEERRLAEQR 807
GEP + + + + L ++FLR Q +E K+R EA + ++LR EE + + LAE++
Sbjct: 338 GEPSSIVNVPGESTLRRDFLRLQ-QENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQ 396
Query: 808 ARIQQEYEE----------EQEKKREKEEEQRLKNEEHIRLAEE---RQKEAERKKKEEE 854
RI+Q+ E+ E+E +R++E EQR + +E R EE R+KE E +++ EE
Sbjct: 397 KRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEE 456
Query: 855 EKYNLQL-QHYCERDNLIGEETKHM 878
EK ++ Q Y R + EE +H+
Sbjct: 457 EKRRVEREQEYIRRQ--LEEEQRHL 479
Score = 65.9 bits (159), Expect = 2e-10
Identities = 63/199 (31%), Positives = 97/199 (48%), Gaps = 41/199 (20%)
Query: 761 ELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERRLAEQRARIQQEYE----E 816
E Q+++QE YK L + E+++R E ++E+ R EE++ R E+ AR QQE E E
Sbjct: 378 EQQLREQEEYKRQL---LAERQKRIEQQKEQRRRLEEQQRR---EREARRQQEREQRRRE 431
Query: 817 EQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKK------EEEEKY--NLQLQHYCERD 868
++EK+R +E E+R K EE R AEE ++ ER+++ EEE+++ LQ Q E+
Sbjct: 432 QEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQA 491
Query: 869 NLIGEETK----HMRQPSPIVPALQNKIAS-----------KLQRPPSVDSIIRSFIHES 913
L+ + + H +QP P P + S R V+ R H S
Sbjct: 492 MLLHDHRRPHPQHSQQPPP--PQQERSKPSFHAPEPKAHYEPADRAREVEDRFRKTNHSS 549
Query: 914 ------SMSRAQSPPVPAR 926
R PPVP+R
Sbjct: 550 PEAQSKQTGRVLEPPVPSR 568
Score = 41.6 bits (96), Expect = 0.005
Identities = 50/215 (23%), Positives = 85/215 (39%), Gaps = 56/215 (26%)
Query: 779 EEKKQREEAERERLRIAEEKEERRLAEQRARIQQEYEEEQEKKREKE--EEQRLKNEEHI 836
EE+++ E E E I E L R+QQE +E E R ++ +EQ+L+ +E
Sbjct: 328 EEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEY 387
Query: 837 RLAEERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKL 896
+ RQ AER+K+ E++K E+ + E+ + R+
Sbjct: 388 K----RQLLAERQKRIEQQK---------EQRRRLEEQQRRERE---------------- 418
Query: 897 QRPPSVDSIIRSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLRSEERR 956
+R Q + Q R E+E+K + EL RK+ E RR
Sbjct: 419 -------------------ARRQQ-----EREQRRREQEEKRRLEELERRRKE-EEERRR 453
Query: 957 LQERLLHMDSDDEIPIRKKERNPMDIFDMARHRLQ 991
+E ++ + E R+ E + + + LQ
Sbjct: 454 AEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQ 488
Score = 36.2 bits (82), Expect = 0.20
Identities = 44/200 (22%), Positives = 90/200 (45%), Gaps = 28/200 (14%)
Query: 93 PNSQQTRGSLGIDYGLSLPLGEDYERKKHKLKEELRQDYRRYLTQGITQGKRKKNFLSTS 152
PN +Q R + L D RKK K+E +Y + + ++ +
Sbjct: 293 PNERQVR--------IQLKDHIDRTRKKRGEKDETEYEY--------SGSEEEEEEVPEQ 336
Query: 153 ETDPSTLGVSLPIGERLSAKERLKLER-NKEYNQFLRGKE--------ESSEKFRQVEKS 203
E +PS++ V++P GE ++ L+L++ NKE ++ LR ++ E E RQ+
Sbjct: 337 EGEPSSI-VNVP-GESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAE 394
Query: 204 TEPKSQRNKKPIGQVKPDLTSQIQTSCENSEGPRKDVLTPSEAYEELLNQRRLEEDRYRQ 263
+ + ++ K+ +++ + + + R+ EEL +R+ EE+R R
Sbjct: 395 RQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRA 454
Query: 264 LDDEIEL-RNRRIIKKANEE 282
+++ + R + I++ EE
Sbjct: 455 EEEKRRVEREQEYIRRQLEE 474
Score = 33.9 bits (76), Expect = 1.0
Identities = 54/247 (21%), Positives = 102/247 (41%), Gaps = 31/247 (12%)
Query: 758 PPTELQIKQQELYKNFLRF----QIEEKKQREEAER--ERLRIAEEKEERRLAEQRARIQ 811
PP L+ K+ K F F ++ QR E+ + I ++ ER++ R +++
Sbjct: 249 PPPRLKSKKWS--KKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQV---RIQLK 303
Query: 812 QEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCERDNL- 870
+ ++K+ EK+E E +EE ++E ++ E N+ + RD L
Sbjct: 304 DHIDRTRKKRGEKDE-----TEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLR 358
Query: 871 IGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPARKNQL 930
+ +E K + AL+ + + Q+ + R + E + + +K Q
Sbjct: 359 LQQENKERSE------ALRRQQLLQEQQLREQEEYKRQLLAE------RQKRIEQQKEQR 406
Query: 931 RAEEEKKNVIMELSEMRKQLRSEERRLQERLLHMDSDDEIPIRKKERNPMDIFDMARHRL 990
R EE++ E R+Q R + RR QE ++ + ++ER + R
Sbjct: 407 RRLEEQQR--REREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVERE 464
Query: 991 QAPVRRQ 997
Q +RRQ
Sbjct: 465 QEYIRRQ 471
Score = 31.2 bits (69), Expect = 6.5
Identities = 24/89 (26%), Positives = 43/89 (48%), Gaps = 16/89 (17%)
Query: 587 VTHQLAQP--VVNTVGQNELKITSDQVINSGLIFEDKPKPSKQSLQSYQEALQQQIRERE 644
V Q +P +VN G++ L+ L + + K ++L+ Q +QQ+RE+E
Sbjct: 333 VPEQEGEPSSIVNVPGESTLR-------RDFLRLQQENKERSEALRRQQLLQEQQLREQE 385
Query: 645 E-------RRKKEREEKEEYEAKLEAEMR 666
E R+K E+++E +LE + R
Sbjct: 386 EYKRQLLAERQKRIEQQKEQRRRLEEQQR 414
Score = 30.8 bits (68), Expect = 8.5
Identities = 17/49 (34%), Positives = 28/49 (57%), Gaps = 1/49 (2%)
Query: 617 IFEDKPKPSKQSLQSYQEALQQQIREREERRKKEREE-KEEYEAKLEAE 664
+ ++ K +Q + + +QQ RERE RR++ERE+ + E E K E
Sbjct: 391 LLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLE 439
>gi|22035602 mitogen-activated protein kinase kinase kinase kinase 4
isoform 1 [Homo sapiens]
Length = 1166
Score = 67.0 bits (162), Expect = 1e-10
Identities = 49/145 (33%), Positives = 82/145 (56%), Gaps = 25/145 (17%)
Query: 756 GEPPTELQIK-QQELYKNFLRFQIEEKKQREEA-------ERERLRIAEEKEERRLAEQR 807
GEP + + + + L ++FLR Q +E K+R EA + ++LR EE + + LAE++
Sbjct: 338 GEPSSIVNVPGESTLRRDFLRLQ-QENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQ 396
Query: 808 ARIQQEYEE----------EQEKKREKEEEQRLKNEEHIRLAEE---RQKEAERKKKEEE 854
RI+Q+ E+ E+E +R++E EQR + +E R EE R+KE E +++ EE
Sbjct: 397 KRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEE 456
Query: 855 EKYNLQL-QHYCERDNLIGEETKHM 878
EK ++ Q Y R + EE +H+
Sbjct: 457 EKRRVEREQEYIRRQ--LEEEQRHL 479
Score = 65.1 bits (157), Expect = 4e-10
Identities = 50/139 (35%), Positives = 81/139 (58%), Gaps = 22/139 (15%)
Query: 761 ELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERRLAEQRARIQQEYE----E 816
E Q+++QE YK L + E+++R E ++E+ R EE++ R E+ AR QQE E E
Sbjct: 378 EQQLREQEEYKRQL---LAERQKRIEQQKEQRRRLEEQQRR---EREARRQQEREQRRRE 431
Query: 817 EQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKK------EEEEKY--NLQLQHYCERD 868
++EK+R +E E+R K EE R AEE ++ ER+++ EEE+++ LQ Q E+
Sbjct: 432 QEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQA 491
Query: 869 NLIGEETK----HMRQPSP 883
L+ + + H +QP P
Sbjct: 492 MLLHDHRRPHPQHSQQPPP 510
Score = 51.6 bits (122), Expect = 5e-06
Identities = 49/184 (26%), Positives = 82/184 (44%), Gaps = 35/184 (19%)
Query: 779 EEKKQREEAERERLRIAEEKEERRLAEQRARIQQEYEEEQEKKREKE--EEQRLKNEEHI 836
EE+++ E E E I E L R+QQE +E E R ++ +EQ+L+ +E
Sbjct: 328 EEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEY 387
Query: 837 R--LAEERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIAS 894
+ L ERQK E++K E++ L+ Q ER+ +E + R+ + +
Sbjct: 388 KRQLLAERQKRIEQQK---EQRRRLEEQQRREREARRQQEREQRRREQE-----EKRRLE 439
Query: 895 KLQRPPSVDSIIRSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLRSEE 954
+L+R + + + RAEEEK+ V E +R+QL E+
Sbjct: 440 ELERRRKEE-----------------------EERRRAEEEKRRVEREQEYIRRQLEEEQ 476
Query: 955 RRLQ 958
R L+
Sbjct: 477 RHLE 480
Score = 36.2 bits (82), Expect = 0.20
Identities = 44/200 (22%), Positives = 90/200 (45%), Gaps = 28/200 (14%)
Query: 93 PNSQQTRGSLGIDYGLSLPLGEDYERKKHKLKEELRQDYRRYLTQGITQGKRKKNFLSTS 152
PN +Q R + L D RKK K+E +Y + + ++ +
Sbjct: 293 PNERQVR--------IQLKDHIDRTRKKRGEKDETEYEY--------SGSEEEEEEVPEQ 336
Query: 153 ETDPSTLGVSLPIGERLSAKERLKLER-NKEYNQFLRGKE--------ESSEKFRQVEKS 203
E +PS++ V++P GE ++ L+L++ NKE ++ LR ++ E E RQ+
Sbjct: 337 EGEPSSI-VNVP-GESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAE 394
Query: 204 TEPKSQRNKKPIGQVKPDLTSQIQTSCENSEGPRKDVLTPSEAYEELLNQRRLEEDRYRQ 263
+ + ++ K+ +++ + + + R+ EEL +R+ EE+R R
Sbjct: 395 RQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRA 454
Query: 264 LDDEIEL-RNRRIIKKANEE 282
+++ + R + I++ EE
Sbjct: 455 EEEKRRVEREQEYIRRQLEE 474
Score = 31.2 bits (69), Expect = 6.5
Identities = 24/89 (26%), Positives = 43/89 (48%), Gaps = 16/89 (17%)
Query: 587 VTHQLAQP--VVNTVGQNELKITSDQVINSGLIFEDKPKPSKQSLQSYQEALQQQIRERE 644
V Q +P +VN G++ L+ L + + K ++L+ Q +QQ+RE+E
Sbjct: 333 VPEQEGEPSSIVNVPGESTLR-------RDFLRLQQENKERSEALRRQQLLQEQQLREQE 385
Query: 645 E-------RRKKEREEKEEYEAKLEAEMR 666
E R+K E+++E +LE + R
Sbjct: 386 EYKRQLLAERQKRIEQQKEQRRRLEEQQR 414
Score = 30.8 bits (68), Expect = 8.5
Identities = 17/49 (34%), Positives = 28/49 (57%), Gaps = 1/49 (2%)
Query: 617 IFEDKPKPSKQSLQSYQEALQQQIREREERRKKEREE-KEEYEAKLEAE 664
+ ++ K +Q + + +QQ RERE RR++ERE+ + E E K E
Sbjct: 391 LLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLE 439
>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
isoform 2 [Homo sapiens]
Length = 1320
Score = 67.0 bits (162), Expect = 1e-10
Identities = 49/145 (33%), Positives = 82/145 (56%), Gaps = 25/145 (17%)
Query: 756 GEPPTELQIK-QQELYKNFLRFQIEEKKQREEA-------ERERLRIAEEKEERRLAEQR 807
GEP + + + + L ++FLR Q +E K+R EA + ++LR EE + + LAE++
Sbjct: 338 GEPSSIVNVPGESTLRRDFLRLQ-QENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQ 396
Query: 808 ARIQQEYEE----------EQEKKREKEEEQRLKNEEHIRLAEE---RQKEAERKKKEEE 854
RI+Q+ E+ E+E +R++E EQR + +E R EE R+KE E +++ EE
Sbjct: 397 KRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEE 456
Query: 855 EKYNLQL-QHYCERDNLIGEETKHM 878
EK ++ Q Y R + EE +H+
Sbjct: 457 EKRRVEREQEYIRRQ--LEEEQRHL 479
Score = 62.4 bits (150), Expect = 3e-09
Identities = 57/183 (31%), Positives = 96/183 (52%), Gaps = 31/183 (16%)
Query: 761 ELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERRLAEQRARIQQEYE----E 816
E Q+++QE YK L + E+++R E ++E+ R EE++ R E+ AR QQE E E
Sbjct: 378 EQQLREQEEYKRQL---LAERQKRIEQQKEQRRRLEEQQRR---EREARRQQEREQRRRE 431
Query: 817 EQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKK------EEEEKY--NLQLQHYCERD 868
++EK+R +E E+R K EE R AEE ++ ER+++ EEE+++ LQ Q E+
Sbjct: 432 QEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQA 491
Query: 869 NLIGEETKHMRQPSPIVPALQNKIASKLQRP-PSVDSIIRSFIHESSM---SRAQSPPVP 924
L+ + M +++ A +LQR + + S H+ +Q PP P
Sbjct: 492 MLLECRWREME---------EHRQAERLQRQLQQEQAYLLSLQHDHRRPHPQHSQQPPPP 542
Query: 925 ARK 927
++
Sbjct: 543 QQE 545
Score = 58.5 bits (140), Expect = 4e-08
Identities = 77/329 (23%), Positives = 138/329 (41%), Gaps = 53/329 (16%)
Query: 630 QSYQEALQQQIREREERRKKEREEKE--EYEAKLEAEMRTYNPWGKGGGGAPLR-DAKGN 686
Q + ++ Q+++ +R +K+R EK+ EYE E P +G + + +
Sbjct: 292 QPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGEST 351
Query: 687 LITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAANKSSGHMQTQS 746
L D R+ ++N + R+ +R + + L + A + Q +
Sbjct: 352 LRRDFLRLQQENKE-------RSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKE 404
Query: 747 SPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERRLAEQ 806
R + + E + ++Q+ + R Q EEK++ EE ER R EE+E RR E+
Sbjct: 405 Q---RRRLEEQQRREREARRQQEREQRRREQ-EEKRRLEELERRR---KEEEERRRAEEE 457
Query: 807 RARIQQEYE------EEQEKKREKEEEQRLKNEEHI------RLAEERQKEAERKKKEEE 854
+ R+++E E EE+++ E ++Q L+ + + + E RQ E +++ ++E
Sbjct: 458 KRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQAMLLECRWREMEEHRQAERLQRQLQQE 517
Query: 855 EKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIAS-----------KLQRPPSVD 903
+ Y L LQH R + +H +QP P P + S R V+
Sbjct: 518 QAYLLSLQHDHRRPH-----PQHSQQPPP--PQQERSKPSFHAPEPKAHYEPADRAREVE 570
Query: 904 SIIRSFIHES------SMSRAQSPPVPAR 926
R H S R PPVP+R
Sbjct: 571 DRFRKTNHSSPEAQSKQTGRVLEPPVPSR 599
Score = 51.6 bits (122), Expect = 5e-06
Identities = 49/184 (26%), Positives = 82/184 (44%), Gaps = 35/184 (19%)
Query: 779 EEKKQREEAERERLRIAEEKEERRLAEQRARIQQEYEEEQEKKREKE--EEQRLKNEEHI 836
EE+++ E E E I E L R+QQE +E E R ++ +EQ+L+ +E
Sbjct: 328 EEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEY 387
Query: 837 R--LAEERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIAS 894
+ L ERQK E++K E++ L+ Q ER+ +E + R+ + +
Sbjct: 388 KRQLLAERQKRIEQQK---EQRRRLEEQQRREREARRQQEREQRRREQE-----EKRRLE 439
Query: 895 KLQRPPSVDSIIRSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLRSEE 954
+L+R + + + RAEEEK+ V E +R+QL E+
Sbjct: 440 ELERRRKEE-----------------------EERRRAEEEKRRVEREQEYIRRQLEEEQ 476
Query: 955 RRLQ 958
R L+
Sbjct: 477 RHLE 480
Score = 40.4 bits (93), Expect = 0.011
Identities = 84/424 (19%), Positives = 165/424 (38%), Gaps = 76/424 (17%)
Query: 587 VTHQLAQP--VVNTVGQNELKITSDQVINSGLIFEDKPKPSKQSLQSYQEALQQQIRERE 644
V Q +P +VN G++ L+ L + + K ++L+ Q +QQ+RE+E
Sbjct: 333 VPEQEGEPSSIVNVPGESTLR-------RDFLRLQQENKERSEALRRQQLLQEQQLREQE 385
Query: 645 E-------RRKKEREEKEEYEAKLEAEMRTYNPWGKGGGGAPLRDAKGNLITDLNRMHRQ 697
E R+K E+++E +LE + R R+A+ + R
Sbjct: 386 EYKRQLLAERQKRIEQQKEQRRRLEEQQRRE------------REARRQQEREQRR---- 429
Query: 698 NIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAANKSSGHMQTQSSPFARGNVFGE 757
R E+KR + L+ E A + ++ + R E
Sbjct: 430 ----------REQEEKRRLEELE---RRRKEEEERRRAEEEKRRVEREQEYIRR--QLEE 474
Query: 758 PPTELQIKQQELYKN---FLRFQIEEKKQREEAERERLRIAEEK--------EERRLAEQ 806
L++ QQ+L + L + E ++ +AER + ++ +E+ + RR Q
Sbjct: 475 EQRHLEVLQQQLLQEQAMLLECRWREMEEHRQAERLQRQLQQEQAYLLSLQHDHRRPHPQ 534
Query: 807 RARIQQEYEEEQEKKREKEEEQRLKNE--EHIRLAEERQKEAERKKKEEEEKYNLQLQHY 864
++ ++E+ K E + E + R E+R ++ E + K Q
Sbjct: 535 HSQQPPPPQQERSKPSFHAPEPKAHYEPADRAREVEDRFRKTNHSSPEAQSK---QTGRV 591
Query: 865 CERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQSPPVP 924
E E+ + PALQ ++Q S + +++ + S S + S P P
Sbjct: 592 LEPPVPSRSESFSNGNSESVHPALQRPAEPQVQW--SHLASLKNNVSPVSRSHSFSDPSP 649
Query: 925 A-RKNQLRAEE----EKKNVIMELSEMRKQLRSEERRLQERLLHMDSDD---EIPIRKKE 976
+ LR+++ + V+ + S+ + + ++ R DSD+ +P+R
Sbjct: 650 KFAHHHLRSQDPCPPSRSEVLSQSSDSKSEAPDPTQKAWSR---SDSDEVPPRVPVRTTS 706
Query: 977 RNPM 980
R+P+
Sbjct: 707 RSPV 710
Score = 39.7 bits (91), Expect = 0.018
Identities = 52/243 (21%), Positives = 107/243 (44%), Gaps = 30/243 (12%)
Query: 93 PNSQQTRGSLGIDYGLSLPLGEDYERKKHKLKEELRQDYRRYLTQGITQGKRKKNFLSTS 152
PN +Q R + L D RKK K+E +Y + + ++ +
Sbjct: 293 PNERQVR--------IQLKDHIDRTRKKRGEKDETEYEY--------SGSEEEEEEVPEQ 336
Query: 153 ETDPSTLGVSLPIGERLSAKERLKLER-NKEYNQFLRGKE--------ESSEKFRQVEKS 203
E +PS++ V++P GE ++ L+L++ NKE ++ LR ++ E E RQ+
Sbjct: 337 EGEPSSI-VNVP-GESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAE 394
Query: 204 TEPKSQRNKKPIGQVKPDLTSQIQTSCENSEGPRKDVLTPSEAYEELLNQRRLEEDRYRQ 263
+ + ++ K+ +++ + + + R+ EEL +R+ EE+R R
Sbjct: 395 RQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRA 454
Query: 264 LDDEIEL-RNRRIIKKANEEV--GISNLKHQRFASKAGIPDRRFHRFNEDRVFDRRYHRP 320
+++ + R + I++ EE + L+ Q +A + + R+ E R +R +
Sbjct: 455 EEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQAMLLECRWREMEEHRQAERLQRQL 514
Query: 321 DQD 323
Q+
Sbjct: 515 QQE 517
Score = 33.9 bits (76), Expect = 1.0
Identities = 54/247 (21%), Positives = 102/247 (41%), Gaps = 31/247 (12%)
Query: 758 PPTELQIKQQELYKNFLRF----QIEEKKQREEAER--ERLRIAEEKEERRLAEQRARIQ 811
PP L+ K+ K F F ++ QR E+ + I ++ ER++ R +++
Sbjct: 249 PPPRLKSKKWS--KKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQV---RIQLK 303
Query: 812 QEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCERDNL- 870
+ ++K+ EK+E E +EE ++E ++ E N+ + RD L
Sbjct: 304 DHIDRTRKKRGEKDE-----TEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLR 358
Query: 871 IGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPARKNQL 930
+ +E K + AL+ + + Q+ + R + E + + +K Q
Sbjct: 359 LQQENKERSE------ALRRQQLLQEQQLREQEEYKRQLLAE------RQKRIEQQKEQR 406
Query: 931 RAEEEKKNVIMELSEMRKQLRSEERRLQERLLHMDSDDEIPIRKKERNPMDIFDMARHRL 990
R EE++ E R+Q R + RR QE ++ + ++ER + R
Sbjct: 407 RRLEEQQR--REREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVERE 464
Query: 991 QAPVRRQ 997
Q +RRQ
Sbjct: 465 QEYIRRQ 471
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 66.6 bits (161), Expect = 1e-10
Identities = 65/295 (22%), Positives = 137/295 (46%), Gaps = 38/295 (12%)
Query: 619 EDKPKPSKQSLQSYQEALQQQ---IREREERRKKEREEKEEYEAKL-EAEMRTYNPWGKG 674
E+K ++ +Q +E + +Q IRE+EE+ ++ E+ E E K+ E E + + K
Sbjct: 296 EEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEK- 354
Query: 675 GGGAPLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDA 734
+R+ + + +M RQ + D + E + + + E + +
Sbjct: 355 -----IREQEEKIREQEEKMWRQE-EKIREQDEKIQEQEEEMWRQE--------EKIREQ 400
Query: 735 ANKSSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRI 794
K M Q E +++ +++E+++ +I E ++ + + E+LR
Sbjct: 401 EEKRQEKMWRQEKKMR------EQDEKIREQEEEMWRQ--EEKIRELEEMMQDQEEKLRE 452
Query: 795 AEEK---EERRLAEQRARIQQEYEEEQEKKRE--------KEEEQRLKNEEHIRLAEERQ 843
EEK EE ++ EQ +IQ++ E+ QE++ + K+EE+ + EE + EE+
Sbjct: 453 VEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKM 512
Query: 844 KEAERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQR 898
E E K +E+EEK Q + E++ + ++ + M++ + L+ ++ Q+
Sbjct: 513 WEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQK 567
Score = 64.7 bits (156), Expect = 5e-10
Identities = 83/362 (22%), Positives = 147/362 (40%), Gaps = 52/362 (14%)
Query: 648 KKEREEKEEYEAKLEAEMRTYNPWGKGGGGAPLRDAKGNLITD-LNRMHRQNIDAY---- 702
KK +E+ E + PW + G + + +L+ + L+ H + Y
Sbjct: 136 KKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKL 195
Query: 703 -HNPDARTYEDKRAVVSLDPNLATSNAENLEDAANKSSGHMQTQSS------PFARGNVF 755
DA + E R ++ D L NAE E S + Q + R +
Sbjct: 196 TKERDAPSLELYRNTIT-DEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLL 254
Query: 756 GEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERRLAEQRARIQQEYE 815
P +LQ++ L K + K Q + E E + +++E ++ Q +IQ++ E
Sbjct: 255 -LPQQQLQVEADRLGKELQ--SVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEE 311
Query: 816 E--EQEKKREKEEEQRLKNEEHIR--------------LAEERQKEAERKKKEEEEKYNL 859
+ EQE K ++EE+ + EE + EE+ +E E K +E+EEK
Sbjct: 312 KMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWR 371
Query: 860 QLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQ 919
Q + E+D I E+ + M + + + K K+ R + R Q
Sbjct: 372 QEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWR-------------QEKKMREQ 418
Query: 920 SPPVPARKNQLRAEEEKKNVIMELSEM----RKQLRSEERRLQERLLHMDSDDEIPIRKK 975
+ ++ ++ +EEK I EL EM ++LR E ++QE M +E R++
Sbjct: 419 DEKIREQEEEMWRQEEK---IRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQE 475
Query: 976 ER 977
E+
Sbjct: 476 EK 477
Score = 62.0 bits (149), Expect = 3e-09
Identities = 68/344 (19%), Positives = 141/344 (40%), Gaps = 67/344 (19%)
Query: 627 QSLQSYQEALQQQIRE----------REERRKKEREEKEEYEAKL-EAEMRTYNPWGKGG 675
+ LQS LQ Q+ E +EE+ ++ E+ +E E K+ E E++
Sbjct: 269 KELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELK--------- 319
Query: 676 GGAPLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAA 735
+R+ + + +MH Q R EDK E + +
Sbjct: 320 ----IREQEEKMWRQEEKMHEQE------EKIREQEDKM----------WRQEEKIREQE 359
Query: 736 NKSSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIA 795
K + + + + E ++Q +++E+++ + + +E+K++E+ R+ ++
Sbjct: 360 EKIR---EQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMR 416
Query: 796 EEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEE 855
E+ E+ R E+ Q+E E E+ + +EE+ + EE ++ EE+ +E E K + +EE
Sbjct: 417 EQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEE 476
Query: 856 KYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSM 915
K Q + ++ L+ +E K Q + + E M
Sbjct: 477 KIQEQEEKTWRQEKLLKQEEKIWEQEE------------------------KMWRQEEKM 512
Query: 916 SRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLRSEERRLQE 959
+ + R EE+ + + L + ++++ +E RLQE
Sbjct: 513 WEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQE 556
Score = 52.0 bits (123), Expect = 4e-06
Identities = 64/290 (22%), Positives = 138/290 (47%), Gaps = 23/290 (7%)
Query: 617 IFEDKPKPSKQSLQSYQEALQQQIREREERRKKEREEKEEYEAKL-EAEMRTYNPWGKGG 675
I E + K +Q + +++ +++IRE+E++ ++ E+ E E K+ E E + + K
Sbjct: 320 IREQEEKMWRQEEKMHEQ--EEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEK-- 375
Query: 676 GGAPLRDAKGNLITDLNRMHRQNIDAYHNPDART---YEDKRAVVSLDPNLATSNAE--N 730
+R+ + M RQ + R + ++ + D + E
Sbjct: 376 ----IREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWR 431
Query: 731 LEDAANKSSGHMQTQSSPFAR-GNVFGEPPTELQIKQQELYKNFLRFQIEEKK--QREEA 787
E+ + MQ Q E ++Q +++++ + + Q +E+K ++E+
Sbjct: 432 QEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKL 491
Query: 788 ERERLRIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRL--AEERQKE 845
++ +I E++E+ E++ Q+E +EQE+K +++EE +++ E+ +RL EE+ +E
Sbjct: 492 LKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEE-KMR-EQEVRLWQQEEKMQE 549
Query: 846 AERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASK 895
E + +E EE+ +L E G E+ R P+ + P LQ ++ S+
Sbjct: 550 QEVRLQELEERLG-KLGQKAELLGGAGRESGSQRLPT-LTPILQVELKSQ 597
Score = 35.0 bits (79), Expect = 0.45
Identities = 69/366 (18%), Positives = 155/366 (42%), Gaps = 41/366 (11%)
Query: 114 EDYERKKHKLKEELR--QDYRRYLTQGITQGKRKKNFLSTS------ETDPSTLGVSLPI 165
E+ + K +L+E+LR + + + + KRK + + LG L
Sbjct: 214 EELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKEL-- 271
Query: 166 GERLSAKERLKLERNKEYNQFLRGKEESSEKFRQVEK--STEPKSQRNKKPIGQVKPDLT 223
+ +SAK + ++E N+ +N L +++ + +RQ EK E K + I + + +
Sbjct: 272 -QSVSAKLQAQVEENELWN--LLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMW 328
Query: 224 SQIQTSCENSEGPRKDVLTPSEAYEELLNQRRLEEDRYRQLDDEIELRNRRIIKKANEEV 283
Q + E E R+ E++ R +E++ R+ ++++ R I++ +E+
Sbjct: 329 RQEEKMHEQEEKIREQEDKMWRQEEKI----REQEEKIREQEEKM-WRQEEKIREQDEK- 382
Query: 284 GISNLKHQRFASKAGIPDRRFHRFNEDRVFDRRYHRPDQDPEVSEEMDERFRYESDFDRR 343
I + + + + I ++ R +++++ + +QD ++ E+ +E +R E
Sbjct: 383 -IQEQEEEMWRQEEKIREQEEKR--QEKMWRQEKKMREQDEKIREQEEEMWRQEEKIREL 439
Query: 344 LSRVYTNDRMHRNKRGNMPP----MEHDGDVIEQSNIRISSAENKSAPDNETSKSAN--- 396
+ + R M M+ + I++ +I E K+ + K
Sbjct: 440 EEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIW 499
Query: 397 --QDTCSPFAGMLFGGEDR-----ELIQRRKEKYR---LELLEQMAEQQRNKRREKDLEL 446
++ ++ E++ E +QR++EK R + L +Q + Q + R ++LE
Sbjct: 500 EQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEE 559
Query: 447 RVAASG 452
R+ G
Sbjct: 560 RLGKLG 565
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 66.6 bits (161), Expect = 1e-10
Identities = 65/295 (22%), Positives = 137/295 (46%), Gaps = 38/295 (12%)
Query: 619 EDKPKPSKQSLQSYQEALQQQ---IREREERRKKEREEKEEYEAKL-EAEMRTYNPWGKG 674
E+K ++ +Q +E + +Q IRE+EE+ ++ E+ E E K+ E E + + K
Sbjct: 296 EEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEK- 354
Query: 675 GGGAPLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDA 734
+R+ + + +M RQ + D + E + + + E + +
Sbjct: 355 -----IREQEEKIREQEEKMWRQE-EKIREQDEKIQEQEEEMWRQE--------EKIREQ 400
Query: 735 ANKSSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRI 794
K M Q E +++ +++E+++ +I E ++ + + E+LR
Sbjct: 401 EEKRQEKMWRQEKKMR------EQDEKIREQEEEMWRQ--EEKIRELEEMMQDQEEKLRE 452
Query: 795 AEEK---EERRLAEQRARIQQEYEEEQEKKRE--------KEEEQRLKNEEHIRLAEERQ 843
EEK EE ++ EQ +IQ++ E+ QE++ + K+EE+ + EE + EE+
Sbjct: 453 VEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKM 512
Query: 844 KEAERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQR 898
E E K +E+EEK Q + E++ + ++ + M++ + L+ ++ Q+
Sbjct: 513 WEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQK 567
Score = 64.7 bits (156), Expect = 5e-10
Identities = 83/362 (22%), Positives = 147/362 (40%), Gaps = 52/362 (14%)
Query: 648 KKEREEKEEYEAKLEAEMRTYNPWGKGGGGAPLRDAKGNLITD-LNRMHRQNIDAY---- 702
KK +E+ E + PW + G + + +L+ + L+ H + Y
Sbjct: 136 KKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKL 195
Query: 703 -HNPDARTYEDKRAVVSLDPNLATSNAENLEDAANKSSGHMQTQSS------PFARGNVF 755
DA + E R ++ D L NAE E S + Q + R +
Sbjct: 196 TKERDALSLELYRNTIT-DEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLL 254
Query: 756 GEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERRLAEQRARIQQEYE 815
P +LQ++ L K + K Q + E E + +++E ++ Q +IQ++ E
Sbjct: 255 -LPQQQLQVEADRLGKELQ--SVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEE 311
Query: 816 E--EQEKKREKEEEQRLKNEEHIR--------------LAEERQKEAERKKKEEEEKYNL 859
+ EQE K ++EE+ + EE + EE+ +E E K +E+EEK
Sbjct: 312 KMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWR 371
Query: 860 QLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQ 919
Q + E+D I E+ + M + + + K K+ R + R Q
Sbjct: 372 QEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWR-------------QEKKMREQ 418
Query: 920 SPPVPARKNQLRAEEEKKNVIMELSEM----RKQLRSEERRLQERLLHMDSDDEIPIRKK 975
+ ++ ++ +EEK I EL EM ++LR E ++QE M +E R++
Sbjct: 419 DEKIREQEEEMWRQEEK---IRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQE 475
Query: 976 ER 977
E+
Sbjct: 476 EK 477
Score = 62.0 bits (149), Expect = 3e-09
Identities = 68/344 (19%), Positives = 141/344 (40%), Gaps = 67/344 (19%)
Query: 627 QSLQSYQEALQQQIRE----------REERRKKEREEKEEYEAKL-EAEMRTYNPWGKGG 675
+ LQS LQ Q+ E +EE+ ++ E+ +E E K+ E E++
Sbjct: 269 KELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELK--------- 319
Query: 676 GGAPLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAA 735
+R+ + + +MH Q R EDK E + +
Sbjct: 320 ----IREQEEKMWRQEEKMHEQE------EKIREQEDKM----------WRQEEKIREQE 359
Query: 736 NKSSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIA 795
K + + + + E ++Q +++E+++ + + +E+K++E+ R+ ++
Sbjct: 360 EKIR---EQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMR 416
Query: 796 EEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEE 855
E+ E+ R E+ Q+E E E+ + +EE+ + EE ++ EE+ +E E K + +EE
Sbjct: 417 EQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEE 476
Query: 856 KYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSM 915
K Q + ++ L+ +E K Q + + E M
Sbjct: 477 KIQEQEEKTWRQEKLLKQEEKIWEQEE------------------------KMWRQEEKM 512
Query: 916 SRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLRSEERRLQE 959
+ + R EE+ + + L + ++++ +E RLQE
Sbjct: 513 WEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQE 556
Score = 52.0 bits (123), Expect = 4e-06
Identities = 64/290 (22%), Positives = 138/290 (47%), Gaps = 23/290 (7%)
Query: 617 IFEDKPKPSKQSLQSYQEALQQQIREREERRKKEREEKEEYEAKL-EAEMRTYNPWGKGG 675
I E + K +Q + +++ +++IRE+E++ ++ E+ E E K+ E E + + K
Sbjct: 320 IREQEEKMWRQEEKMHEQ--EEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEK-- 375
Query: 676 GGAPLRDAKGNLITDLNRMHRQNIDAYHNPDART---YEDKRAVVSLDPNLATSNAE--N 730
+R+ + M RQ + R + ++ + D + E
Sbjct: 376 ----IREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWR 431
Query: 731 LEDAANKSSGHMQTQSSPFAR-GNVFGEPPTELQIKQQELYKNFLRFQIEEKK--QREEA 787
E+ + MQ Q E ++Q +++++ + + Q +E+K ++E+
Sbjct: 432 QEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKL 491
Query: 788 ERERLRIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRL--AEERQKE 845
++ +I E++E+ E++ Q+E +EQE+K +++EE +++ E+ +RL EE+ +E
Sbjct: 492 LKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEE-KMR-EQEVRLWQQEEKMQE 549
Query: 846 AERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASK 895
E + +E EE+ +L E G E+ R P+ + P LQ ++ S+
Sbjct: 550 QEVRLQELEERLG-KLGQKAELLGGAGRESGSQRLPT-LTPILQVELKSQ 597
Score = 35.8 bits (81), Expect = 0.26
Identities = 71/381 (18%), Positives = 161/381 (42%), Gaps = 41/381 (10%)
Query: 99 RGSLGIDYGLSLPLGEDYERKKHKLKEELR--QDYRRYLTQGITQGKRKKNFLSTS---- 152
R +L ++ + E+ + K +L+E+LR + + + + KRK
Sbjct: 199 RDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQ 258
Query: 153 --ETDPSTLGVSLPIGERLSAKERLKLERNKEYNQFLRGKEESSEKFRQVEK--STEPKS 208
+ + LG L + +SAK + ++E N+ +N L +++ + +RQ EK E K
Sbjct: 259 QLQVEADRLGKEL---QSVSAKLQAQVEENELWN--LLNQQQEEKMWRQEEKIQEQEEKM 313
Query: 209 QRNKKPIGQVKPDLTSQIQTSCENSEGPRKDVLTPSEAYEELLNQRRLEEDRYRQLDDEI 268
+ I + + + Q + E E R+ E++ R +E++ R+ ++++
Sbjct: 314 CEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKI----REQEEKIREQEEKM 369
Query: 269 ELRNRRIIKKANEEVGISNLKHQRFASKAGIPDRRFHRFNEDRVFDRRYHRPDQDPEVSE 328
R I++ +E+ I + + + + I ++ R +++++ + +QD ++ E
Sbjct: 370 -WRQEEKIREQDEK--IQEQEEEMWRQEEKIREQEEKR--QEKMWRQEKKMREQDEKIRE 424
Query: 329 EMDERFRYESDFDRRLSRVYTNDRMHRNKRGNMPP----MEHDGDVIEQSNIRISSAENK 384
+ +E +R E + + R M M+ + I++ +I E K
Sbjct: 425 QEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEK 484
Query: 385 SAPDNETSKSAN-----QDTCSPFAGMLFGGEDR-----ELIQRRKEKYR---LELLEQM 431
+ + K ++ ++ E++ E +QR++EK R + L +Q
Sbjct: 485 TWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQE 544
Query: 432 AEQQRNKRREKDLELRVAASG 452
+ Q + R ++LE R+ G
Sbjct: 545 EKMQEQEVRLQELEERLGKLG 565
>gi|120953300 leucine-rich repeats and IQ motif containing 1 isoform
1 [Homo sapiens]
Length = 1722
Score = 66.2 bits (160), Expect = 2e-10
Identities = 66/231 (28%), Positives = 114/231 (49%), Gaps = 31/231 (13%)
Query: 772 NFLRFQIEEK-KQREEAERERLRIAEEKEERRLAEQRARIQQEYEEEQEK--------KR 822
NF ++EEK +Q EA +E+ + E+KE++ L QR R +++++EE+EK K
Sbjct: 157 NFGYCEVEEKCRQSFEAWQEKQKELEDKEKQTLKAQRDREEKQFQEEEEKRHCWMKQFKV 216
Query: 823 EKEEEQRLKNEEHIRLAEERQKE----AERKKKEEEEKYNLQLQHYCERDNLIGEETKHM 878
EK++ + ++ +E ++ +E KE E+ K+ EE NL LQ ER ++ K
Sbjct: 217 EKKKLENIQKQEQDKMNDELYKEEKIWKEKFKQHEEYIRNLHLQMEEERTRFKDQQEKEK 276
Query: 879 RQPSPIVPALQNKIASKLQRP-------PSVDSIIRSFIHESSMSRAQSPPVPARKNQLR 931
+ QN A K+Q II+ I ES +AQ K + +
Sbjct: 277 NS----LLKQQNNAAVKIQAKYKAFVAYQKYGPIIKEQI-ESKKRKAQEWKEKEAKIRQK 331
Query: 932 AEEEKKNVIME--LSEMRKQLRSEERRLQERLLHMDSDDEIPIRKKERNPM 980
EE +K + E + E RK+ + EER+ +E+ + +++ I K+ER +
Sbjct: 332 EEENRKRLEEEQRIKEERKKQKEEERKRREK----EYEEKKNIVKQEREQL 378
Score = 62.4 bits (150), Expect = 3e-09
Identities = 46/146 (31%), Positives = 75/146 (51%), Gaps = 31/146 (21%)
Query: 763 QIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERRLA------------------ 804
+ KQ E Y L Q+EE++ R + ++E+ + + K++ A
Sbjct: 246 KFKQHEEYIRNLHLQMEEERTRFKDQQEKEKNSLLKQQNNAAVKIQAKYKAFVAYQKYGP 305
Query: 805 ------EQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAE----RKKKEEE 854
E + R QE++E++ K R+KEEE R + EE R+ EER+K+ E R++KE E
Sbjct: 306 IIKEQIESKKRKAQEWKEKEAKIRQKEEENRKRLEEEQRIKEERKKQKEEERKRREKEYE 365
Query: 855 EKYNLQLQHYCERDNLIGEETKHMRQ 880
EK N+ Q ER+ LI +E +R+
Sbjct: 366 EKKNIVKQ---EREQLISKEKIILRE 388
Score = 48.1 bits (113), Expect = 5e-05
Identities = 103/538 (19%), Positives = 214/538 (39%), Gaps = 91/538 (16%)
Query: 593 QPVVNTVGQNELKITSDQVINSGLIFEDKPKPSKQSLQSYQEALQQQIREREERRKKERE 652
+P + + +E + D IN G + + + +QS +++QE Q+++ ++E++ K +
Sbjct: 137 EPSPHDLPMDEHVLPDDADINFG--YCEVEEKCRQSFEAWQEK-QKELEDKEKQTLKAQR 193
Query: 653 EKEEYEAKLEAEMRTYNPWGKGGGGAPLRDAKGNLITDLNRMHRQNIDAYHNPDARTYED 712
++EE + + E E R + W K + + ++ + + ++ + + +++
Sbjct: 194 DREEKQFQEEEEKR--HCWMKQF------KVEKKKLENIQKQEQDKMNDELYKEEKIWKE 245
Query: 713 K-RAVVSLDPNLATSNAEN---LEDAANKSSGHMQTQSSPFARGNVFGEPPTELQIKQQE 768
K + NL E +D K + Q + A +K Q
Sbjct: 246 KFKQHEEYIRNLHLQMEEERTRFKDQQEKEKNSLLKQQNNAA-------------VKIQA 292
Query: 769 LYKNFLRFQ---------IEEKKQREEAERERLRIAEEKEE--RRLAEQRARIQQEY--- 814
YK F+ +Q IE KK++ + +E+ +KEE R+ E+ RI++E
Sbjct: 293 KYKAFVAYQKYGPIIKEQIESKKRKAQEWKEKEAKIRQKEEENRKRLEEEQRIKEERKKQ 352
Query: 815 EEEQEKKREKE----------EEQRLKNEEHIRLAEERQKE---AERKKKEEEEKYNLQL 861
+EE+ K+REKE E ++L ++E I L E+ ++ + KK +L L
Sbjct: 353 KEEERKRREKEYEEKKNIVKQEREQLISKEKIILREDASQQLIISSALKKSGYNNKHLSL 412
Query: 862 QHYCE-----RDNLIGEETK-------------HMRQPSPIVPALQNKIASKLQRPPSVD 903
+ NL+ E +K +M++ L+ I KL+ S
Sbjct: 413 EDISNDKGDIAKNLVDENSKKQEDVLLWLVEESNMKENVDRQTILKESIQVKLKESISSQ 472
Query: 904 SIIRSFIHESSMSRAQSPPVPAR--KNQLRAEEEKKNVIMELSEMRKQLRSEERRLQERL 961
+I+ F E K + + E + S+++ L+ E+ LQE
Sbjct: 473 TILADFKMEEKNENLAKKRCSEELVKQERKYENTDNKTELGNSDLKGNLK-EQFPLQE-- 529
Query: 962 LHMDSDDEIPIRKKERNP-------------MDIFDMARHRLQAPVRRQSPKGLDAATFQ 1008
L D+ E I K N +I ++ + Q ++ K + +
Sbjct: 530 LKSDAQKEEKIMKHVINENTGQKTQIILGHNQEISEVKTNEEQKIIKDNQQKKIQKVEKE 589
Query: 1009 NVHDFNELKDRDSETRVDLKFMYLDPPRDHHTLEIQQQALLREQQKRLNRIKMQEGAK 1066
+ + N L +D +T V ++ ++++ +L+E++ +++E K
Sbjct: 590 EIQEQNGLLYKDKDTLVISVKQRSLSLTSENSKDVRENVILQEKEIYSKSKEIEENPK 647
>gi|120953243 leucine-rich repeats and IQ motif containing 1 isoform
2 [Homo sapiens]
Length = 1336
Score = 66.2 bits (160), Expect = 2e-10
Identities = 66/231 (28%), Positives = 114/231 (49%), Gaps = 31/231 (13%)
Query: 772 NFLRFQIEEK-KQREEAERERLRIAEEKEERRLAEQRARIQQEYEEEQEK--------KR 822
NF ++EEK +Q EA +E+ + E+KE++ L QR R +++++EE+EK K
Sbjct: 157 NFGYCEVEEKCRQSFEAWQEKQKELEDKEKQTLKAQRDREEKQFQEEEEKRHCWMKQFKV 216
Query: 823 EKEEEQRLKNEEHIRLAEERQKE----AERKKKEEEEKYNLQLQHYCERDNLIGEETKHM 878
EK++ + ++ +E ++ +E KE E+ K+ EE NL LQ ER ++ K
Sbjct: 217 EKKKLENIQKQEQDKMNDELYKEEKIWKEKFKQHEEYIRNLHLQMEEERTRFKDQQEKEK 276
Query: 879 RQPSPIVPALQNKIASKLQRP-------PSVDSIIRSFIHESSMSRAQSPPVPARKNQLR 931
+ QN A K+Q II+ I ES +AQ K + +
Sbjct: 277 NS----LLKQQNNAAVKIQAKYKAFVAYQKYGPIIKEQI-ESKKRKAQEWKEKEAKIRQK 331
Query: 932 AEEEKKNVIME--LSEMRKQLRSEERRLQERLLHMDSDDEIPIRKKERNPM 980
EE +K + E + E RK+ + EER+ +E+ + +++ I K+ER +
Sbjct: 332 EEENRKRLEEEQRIKEERKKQKEEERKRREK----EYEEKKNIVKQEREQL 378
Score = 62.4 bits (150), Expect = 3e-09
Identities = 46/146 (31%), Positives = 75/146 (51%), Gaps = 31/146 (21%)
Query: 763 QIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERRLA------------------ 804
+ KQ E Y L Q+EE++ R + ++E+ + + K++ A
Sbjct: 246 KFKQHEEYIRNLHLQMEEERTRFKDQQEKEKNSLLKQQNNAAVKIQAKYKAFVAYQKYGP 305
Query: 805 ------EQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAE----RKKKEEE 854
E + R QE++E++ K R+KEEE R + EE R+ EER+K+ E R++KE E
Sbjct: 306 IIKEQIESKKRKAQEWKEKEAKIRQKEEENRKRLEEEQRIKEERKKQKEEERKRREKEYE 365
Query: 855 EKYNLQLQHYCERDNLIGEETKHMRQ 880
EK N+ Q ER+ LI +E +R+
Sbjct: 366 EKKNIVKQ---EREQLISKEKIILRE 388
Score = 48.1 bits (113), Expect = 5e-05
Identities = 103/538 (19%), Positives = 214/538 (39%), Gaps = 91/538 (16%)
Query: 593 QPVVNTVGQNELKITSDQVINSGLIFEDKPKPSKQSLQSYQEALQQQIREREERRKKERE 652
+P + + +E + D IN G + + + +QS +++QE Q+++ ++E++ K +
Sbjct: 137 EPSPHDLPMDEHVLPDDADINFG--YCEVEEKCRQSFEAWQEK-QKELEDKEKQTLKAQR 193
Query: 653 EKEEYEAKLEAEMRTYNPWGKGGGGAPLRDAKGNLITDLNRMHRQNIDAYHNPDARTYED 712
++EE + + E E R + W K + + ++ + + ++ + + +++
Sbjct: 194 DREEKQFQEEEEKR--HCWMKQF------KVEKKKLENIQKQEQDKMNDELYKEEKIWKE 245
Query: 713 K-RAVVSLDPNLATSNAEN---LEDAANKSSGHMQTQSSPFARGNVFGEPPTELQIKQQE 768
K + NL E +D K + Q + A +K Q
Sbjct: 246 KFKQHEEYIRNLHLQMEEERTRFKDQQEKEKNSLLKQQNNAA-------------VKIQA 292
Query: 769 LYKNFLRFQ---------IEEKKQREEAERERLRIAEEKEE--RRLAEQRARIQQEY--- 814
YK F+ +Q IE KK++ + +E+ +KEE R+ E+ RI++E
Sbjct: 293 KYKAFVAYQKYGPIIKEQIESKKRKAQEWKEKEAKIRQKEEENRKRLEEEQRIKEERKKQ 352
Query: 815 EEEQEKKREKE----------EEQRLKNEEHIRLAEERQKE---AERKKKEEEEKYNLQL 861
+EE+ K+REKE E ++L ++E I L E+ ++ + KK +L L
Sbjct: 353 KEEERKRREKEYEEKKNIVKQEREQLISKEKIILREDASQQLIISSALKKSGYNNKHLSL 412
Query: 862 QHYCE-----RDNLIGEETK-------------HMRQPSPIVPALQNKIASKLQRPPSVD 903
+ NL+ E +K +M++ L+ I KL+ S
Sbjct: 413 EDISNDKGDIAKNLVDENSKKQEDVLLWLVEESNMKENVDRQTILKESIQVKLKESISSQ 472
Query: 904 SIIRSFIHESSMSRAQSPPVPAR--KNQLRAEEEKKNVIMELSEMRKQLRSEERRLQERL 961
+I+ F E K + + E + S+++ L+ E+ LQE
Sbjct: 473 TILADFKMEEKNENLAKKRCSEELVKQERKYENTDNKTELGNSDLKGNLK-EQFPLQE-- 529
Query: 962 LHMDSDDEIPIRKKERNP-------------MDIFDMARHRLQAPVRRQSPKGLDAATFQ 1008
L D+ E I K N +I ++ + Q ++ K + +
Sbjct: 530 LKSDAQKEEKIMKHVINENTGQKTQIILGHNQEISEVKTNEEQKIIKDNQQKKIQKVEKE 589
Query: 1009 NVHDFNELKDRDSETRVDLKFMYLDPPRDHHTLEIQQQALLREQQKRLNRIKMQEGAK 1066
+ + N L +D +T V ++ ++++ +L+E++ +++E K
Sbjct: 590 EIQEQNGLLYKDKDTLVISVKQRSLSLTSENSKDVRENVILQEKEIYSKSKEIEENPK 647
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 65.5 bits (158), Expect = 3e-10
Identities = 54/230 (23%), Positives = 110/230 (47%), Gaps = 24/230 (10%)
Query: 766 QQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERRLAE---QRARIQQEYEEEQEKKR 822
Q+E + R + E++K+ E ER+R R +EK++R+ E +R R ++E E++++++R
Sbjct: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90
Query: 823 EKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPS 882
EKE +R K E+ R ++R + +KKKE +E+ ER+N E K +
Sbjct: 91 EKERRKR-KKEKKKRERKQRGRRERKKKKERKER---------ERENKQRRERKRKK--- 137
Query: 883 PIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIME 942
+ K + +R + R + + + + + E E+K
Sbjct: 138 ------RRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRER 191
Query: 943 LSEMRKQLRSEERRLQERLLHMDSDDEI--PIRKKERNPMDIFDMARHRL 990
E +K+ R ++ R ++R +D ++ P+R+ N + + + R+R+
Sbjct: 192 KKERKKERRKKKERKKDRKTDRQTDSQVFRPLRESAFNRVTVTGVFRYRI 241
Score = 49.3 bits (116), Expect = 2e-05
Identities = 30/95 (31%), Positives = 59/95 (62%), Gaps = 3/95 (3%)
Query: 765 KQQELYKNFLRFQIEEKKQREE-AERERLRIAEEKEERRLAEQRARIQQEYEEEQEKKRE 823
K++E K R + E +KQR+E E+ER + +EK++R ++ R +++ +E +E++RE
Sbjct: 67 KKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERE 126
Query: 824 KEE--EQRLKNEEHIRLAEERQKEAERKKKEEEEK 856
++ E++ K + +ER++E ER K+E + K
Sbjct: 127 NKQRRERKRKKRRKKKRRKERKREKERGKRERKRK 161
Score = 49.3 bits (116), Expect = 2e-05
Identities = 27/107 (25%), Positives = 66/107 (61%), Gaps = 1/107 (0%)
Query: 761 ELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERRLAEQRARIQQEYEEEQEK 820
E + K++E K + +E+++R++ +++R R + ER+ ++R ++E ++ +E+
Sbjct: 74 ERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRER 133
Query: 821 KREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCER 867
KR+K +++ + +E R E ++E +RKK+++EE+ + ++ ER
Sbjct: 134 KRKKRRKKK-RRKERKREKERGKRERKRKKRKKEEREKKRERNRKER 179
Score = 47.8 bits (112), Expect = 7e-05
Identities = 28/94 (29%), Positives = 56/94 (59%), Gaps = 3/94 (3%)
Query: 765 KQQELYKNFLRFQIEEKKQREEAERERL--RIAEEKEERRLAEQRARIQQEYEEEQEKKR 822
+++E K + E+KQR ER++ R E+E ++ E++ + +++ + +E+KR
Sbjct: 90 REKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKR 149
Query: 823 EKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEK 856
EKE +R + + R EER+K+ ER +KE +++
Sbjct: 150 EKERGKRERKRKK-RKKEEREKKRERNRKERKKE 182
Score = 44.7 bits (104), Expect = 6e-04
Identities = 47/215 (21%), Positives = 95/215 (44%), Gaps = 32/215 (14%)
Query: 642 EREERRKKEREEKEEYEAKLEAEMRTYNPWGKGGGGAPLRDAKGNLITDLNRMHRQNIDA 701
+RE RKKER E+E+ + + E E + GK + +G R+ +
Sbjct: 31 QRESERKKERREREKRKREREKERKRER--GKKEKKKRKKRERGK------ERERKRKER 82
Query: 702 YHNPDARTYEDKRAVVSLDPNLATSNAENLEDAANKSSGHMQTQSSPFARGNVFGEPPTE 761
R +++R + + K G + + R E
Sbjct: 83 EKQRKERREKERR-----------KRKKEKKKRERKQRGRRERKKKK-ERKERERENKQR 130
Query: 762 LQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERRLAEQRARIQQEYEEEQEKK 821
+ K+++ K R + + +K+R + ER+R + +KEER +R R +++ E E++++
Sbjct: 131 RERKRKKRRKKKRRKERKREKERGKRERKRKK--RKKEEREKKRERNRKERKKERERKER 188
Query: 822 REKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEK 856
RE+++E++ +ER+K+ ERKK + ++
Sbjct: 189 RERKKERK----------KERRKKKERKKDRKTDR 213
Score = 37.0 bits (84), Expect = 0.12
Identities = 37/199 (18%), Positives = 81/199 (40%), Gaps = 5/199 (2%)
Query: 815 EEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCERDNLIGE- 873
+ E E+K+E+ E ++ K E ER K+ E+KK+++ E+ + + ER+ E
Sbjct: 31 QRESERKKERREREKRKREREKERKRERGKK-EKKKRKKRERGKERERKRKEREKQRKER 89
Query: 874 ETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPARKNQLRAE 933
K R+ + K + +R + R + R + RK + R E
Sbjct: 90 REKERRKRKKEKKKRERKQRGRRERKKKKE---RKERERENKQRRERKRKKRRKKKRRKE 146
Query: 934 EEKKNVIMELSEMRKQLRSEERRLQERLLHMDSDDEIPIRKKERNPMDIFDMARHRLQAP 993
+++ + RK+ + EER + + E +++ + R + +
Sbjct: 147 RKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERK 206
Query: 994 VRRQSPKGLDAATFQNVHD 1012
R++ + D+ F+ + +
Sbjct: 207 KDRKTDRQTDSQVFRPLRE 225
Score = 36.6 bits (83), Expect = 0.15
Identities = 50/234 (21%), Positives = 96/234 (41%), Gaps = 30/234 (12%)
Query: 625 SKQSLQSYQEALQQQIREREERRKKEREEKEEYEAKLEAEMRTYNPWGKGGGGAPLRDAK 684
SK Q E +++ RERE+R+++ +E++ K E + R GK R+ K
Sbjct: 26 SKPCTQRESERKKER-REREKRKREREKERKRERGKKEKKKRKKRERGKE------RERK 78
Query: 685 GNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAANKSSGHMQT 744
+ R+ + + E K+ E + K
Sbjct: 79 RKEREKQRKERREKERRKRKKEKKKRERKQR----------GRRERKKKKERKERERENK 128
Query: 745 QSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERRLA 804
Q R + + + +++E K + + +K++RE+ +RER R E K+ER
Sbjct: 129 QRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREK-KRERNR-KERKKER--- 183
Query: 805 EQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYN 858
E +E +E+K+E+++E+R K E +RQ +++ + E +N
Sbjct: 184 --------ERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRESAFN 229
Score = 34.7 bits (78), Expect = 0.59
Identities = 47/206 (22%), Positives = 77/206 (37%), Gaps = 29/206 (14%)
Query: 117 ERKKHKLKEELRQDYR---RYLTQGITQGKRKKNFLSTSETDPSTLGVSLPIGERLSA-- 171
ERKK + + E R+ R R +G + K++K E + ER
Sbjct: 35 ERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKER 94
Query: 172 ----KERLKLERNKEYNQFLRGKEESSEKFRQVEKSTEPKSQRNKKPIGQVKPDLTSQIQ 227
KE+ K ER + RG+ E +K + E+ E K +R +K + K + +
Sbjct: 95 RKRKKEKKKRERKQ------RGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERK 148
Query: 228 TSCENSEGPRKDVLTPSEAYEELLNQRRLEEDRYRQLDDEIELRNRRIIKKANEEVGISN 287
E + RK E E+ + R E + R+ + E + R
Sbjct: 149 REKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKER------------- 195
Query: 288 LKHQRFASKAGIPDRRFHRFNEDRVF 313
K +R K DR+ R + +VF
Sbjct: 196 -KKERRKKKERKKDRKTDRQTDSQVF 220
Score = 34.3 bits (77), Expect = 0.77
Identities = 39/193 (20%), Positives = 76/193 (39%), Gaps = 9/193 (4%)
Query: 161 VSLPIGERLSAKERLKLERNKEYNQFLRGKEESSEKFRQVEKSTEPKSQRNKKPIGQVKP 220
+S P +R S +++ + ER K ++ EK R+ E+ + K +R K+ G+ +
Sbjct: 25 ISKPCTQRESERKKERREREK--------RKREREKERKRERGKKEKKKRKKRERGKERE 76
Query: 221 DLTSQIQTSC-ENSEGPRKDVLTPSEAYEELLNQRRLEEDRYRQLDDEIELRNRRIIKKA 279
+ + E E R+ + E RR + + + + E E + RR K+
Sbjct: 77 RKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRK 136
Query: 280 NEEVGISNLKHQRFASKAGIPDRRFHRFNEDRVFDRRYHRPDQDPEVSEEMDERFRYESD 339
+ +R + +R R E+R R +R ++ E + + E
Sbjct: 137 KRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERK 196
Query: 340 FDRRLSRVYTNDR 352
+RR + DR
Sbjct: 197 KERRKKKERKKDR 209
Score = 30.8 bits (68), Expect = 8.5
Identities = 19/71 (26%), Positives = 39/71 (54%), Gaps = 5/71 (7%)
Query: 619 EDKPKPSKQSLQSYQEALQQQIREREERRKKEREEKEEYEAKLEAEMRTYNPWGKGGGGA 678
E + K + + +E +++ RER++ RKKER +K+E + + + +T + +
Sbjct: 167 EREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVFR----- 221
Query: 679 PLRDAKGNLIT 689
PLR++ N +T
Sbjct: 222 PLRESAFNRVT 232
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.130 0.363
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 52,000,161
Number of Sequences: 37866
Number of extensions: 2778887
Number of successful extensions: 58620
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 798
Number of HSP's successfully gapped in prelim test: 1191
Number of HSP's that attempted gapping in prelim test: 17592
Number of HSP's gapped (non-prelim): 17528
length of query: 1256
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1142
effective length of database: 13,930,794
effective search space: 15908966748
effective search space used: 15908966748
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.