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Search of human proteins with 116089284
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|116089284 fibrous sheath interacting protein 1 [Homo
sapiens]
(581 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|116089284 fibrous sheath interacting protein 1 [Homo sapiens] 1136 0.0
gi|109659847 filamin A interacting protein 1-like isoform 3 [Hom... 69 2e-11
gi|109659849 filamin A interacting protein 1-like isoform 2 [Hom... 69 2e-11
gi|109659845 filamin A interacting protein 1-like isoform 1 [Hom... 69 2e-11
gi|71061468 centromere protein E [Homo sapiens] 62 1e-09
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 59 1e-08
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 59 2e-08
gi|41872583 Rho-associated, coiled-coil containing protein kinas... 56 8e-08
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 56 8e-08
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 55 1e-07
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 55 2e-07
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 54 5e-07
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 53 7e-07
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 53 7e-07
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 53 7e-07
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 53 7e-07
gi|46049114 M-phase phosphoprotein 1 [Homo sapiens] 53 7e-07
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 52 2e-06
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 51 3e-06
gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens] 51 3e-06
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 50 4e-06
gi|55770834 centromere protein F [Homo sapiens] 50 4e-06
gi|221219020 NYD-SP11 protein [Homo sapiens] 50 6e-06
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 50 7e-06
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 50 7e-06
gi|30794488 kinesin family member 27 [Homo sapiens] 50 7e-06
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 49 1e-05
gi|7705415 hook homolog 1 [Homo sapiens] 49 1e-05
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 49 1e-05
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 49 1e-05
>gi|116089284 fibrous sheath interacting protein 1 [Homo sapiens]
Length = 581
Score = 1136 bits (2938), Expect = 0.0
Identities = 581/581 (100%), Positives = 581/581 (100%)
Query: 1 MDIIKGNLDGISKPASNSRIRPGSRSSNASLEVLSTEPGSFKVDTASNLNSGKEDHSESS 60
MDIIKGNLDGISKPASNSRIRPGSRSSNASLEVLSTEPGSFKVDTASNLNSGKEDHSESS
Sbjct: 1 MDIIKGNLDGISKPASNSRIRPGSRSSNASLEVLSTEPGSFKVDTASNLNSGKEDHSESS 60
Query: 61 NTENRRTSNDDKQESCSEKIKLAEEGSDEDLDLVQHQIISECSDEPKLKELDSQLQDAIQ 120
NTENRRTSNDDKQESCSEKIKLAEEGSDEDLDLVQHQIISECSDEPKLKELDSQLQDAIQ
Sbjct: 61 NTENRRTSNDDKQESCSEKIKLAEEGSDEDLDLVQHQIISECSDEPKLKELDSQLQDAIQ 120
Query: 121 KMKKLDKILAKKQRREKEIKKQGLEMRIKLWEEIKSAKYSEAWQSKEEMENTKKFLSLTA 180
KMKKLDKILAKKQRREKEIKKQGLEMRIKLWEEIKSAKYSEAWQSKEEMENTKKFLSLTA
Sbjct: 121 KMKKLDKILAKKQRREKEIKKQGLEMRIKLWEEIKSAKYSEAWQSKEEMENTKKFLSLTA 180
Query: 181 VSEETVGPSHEEEDTFSSVFHTQIPPEEYEMQMQKLNKDFTCDVERNESLIKSGKKPFSN 240
VSEETVGPSHEEEDTFSSVFHTQIPPEEYEMQMQKLNKDFTCDVERNESLIKSGKKPFSN
Sbjct: 181 VSEETVGPSHEEEDTFSSVFHTQIPPEEYEMQMQKLNKDFTCDVERNESLIKSGKKPFSN 240
Query: 241 TEKIELRGKHNQDFIKRNIELAKESRNPVVMVDREKKRLVELLKDLDEKDSGLSSSEGDQ 300
TEKIELRGKHNQDFIKRNIELAKESRNPVVMVDREKKRLVELLKDLDEKDSGLSSSEGDQ
Sbjct: 241 TEKIELRGKHNQDFIKRNIELAKESRNPVVMVDREKKRLVELLKDLDEKDSGLSSSEGDQ 300
Query: 301 SGWVVPVKGYELAVTQHQQLAEIDIKLQELSAASPTISSFSPRLENRNNQKPDRDGERNM 360
SGWVVPVKGYELAVTQHQQLAEIDIKLQELSAASPTISSFSPRLENRNNQKPDRDGERNM
Sbjct: 301 SGWVVPVKGYELAVTQHQQLAEIDIKLQELSAASPTISSFSPRLENRNNQKPDRDGERNM 360
Query: 361 EVTPGEKILRNTKEQRDLHNRLREIDEKLKMMKENVLESTSCLSEEQLKCLLDECILKQK 420
EVTPGEKILRNTKEQRDLHNRLREIDEKLKMMKENVLESTSCLSEEQLKCLLDECILKQK
Sbjct: 361 EVTPGEKILRNTKEQRDLHNRLREIDEKLKMMKENVLESTSCLSEEQLKCLLDECILKQK 420
Query: 421 SIIKLSSERKKEDIEDVTPVFPQLSRSIISKLLNESETKVQKTEVEDADMLESEECEASK 480
SIIKLSSERKKEDIEDVTPVFPQLSRSIISKLLNESETKVQKTEVEDADMLESEECEASK
Sbjct: 421 SIIKLSSERKKEDIEDVTPVFPQLSRSIISKLLNESETKVQKTEVEDADMLESEECEASK 480
Query: 481 GYYLTKALTGHNMSEALVTEAENMKCLQFSKDVIISDTKDYFMSKTLGIGRLKRPSFLDD 540
GYYLTKALTGHNMSEALVTEAENMKCLQFSKDVIISDTKDYFMSKTLGIGRLKRPSFLDD
Sbjct: 481 GYYLTKALTGHNMSEALVTEAENMKCLQFSKDVIISDTKDYFMSKTLGIGRLKRPSFLDD 540
Query: 541 PLYGISVSLSSEDQHLKLSSPENTIADEQETKDAAEECKEP 581
PLYGISVSLSSEDQHLKLSSPENTIADEQETKDAAEECKEP
Sbjct: 541 PLYGISVSLSSEDQHLKLSSPENTIADEQETKDAAEECKEP 581
>gi|109659847 filamin A interacting protein 1-like isoform 3 [Homo
sapiens]
Length = 1133
Score = 68.6 bits (166), Expect = 2e-11
Identities = 96/470 (20%), Positives = 197/470 (41%), Gaps = 62/470 (13%)
Query: 51 SGKEDHSESSNTENRRTSNDDKQESCSEKIKLAEEGSDEDLDLVQHQIISECSDEPKLKE 110
+ KE H++ + E R + K ++++ +D D + ++ +E S +L++
Sbjct: 266 NAKETHTKLALAEARVQEEEQKATRLEKELQTQTTKFHQDQDTIMAKLTNEDSQNRQLQQ 325
Query: 111 LDSQLQDAIQKMKKLDKILAKKQRREKEIKKQGLEMRIKLWEEIKSAKYSEAWQSKEEME 170
+ L I ++++ ++ L K + ++IK E+I +Y A E E
Sbjct: 326 KLAALSRQIDELEETNRSLRKAEEELQDIK-----------EKISKGEYGNAGIMAEVEE 374
Query: 171 NTKKFLSLTAVSEETVGPSHEEEDTFSSVFHTQIPPEEYEMQMQKLNKDFTCDVERNESL 230
K+ L + EE + + D + + ++++++++KL+K + ++
Sbjct: 375 LRKRVLDMEGKDEELIKMEEQCRDLNKRLERETLQSKDFKLEVEKLSKRIMALEKLEDAF 434
Query: 231 IKSGKKPFSNTEKIELRGKHNQDFIKRNIELAKESRNPVVMVDREKKRLVELLKDLDEKD 290
KS ++ +S +K N+E + R + +E + L +K+L+ +
Sbjct: 435 NKSKQECYS---------------LKCNLE---KERMTTKQLSQELESLKVRIKELEAIE 476
Query: 291 SGLSSSEGDQSGWVVPVKGYELAV-----TQHQQLAEIDIKLQ----ELSAASPTISSFS 341
S L +E + +K + T ++L + + KLQ +L +++ +
Sbjct: 477 SRLEKTEFTLKEDLTKLKTLTVMFVDERKTMSEKLKKTEDKLQAASSQLQVEQNKVTTVT 536
Query: 342 PRL--ENRNNQKPDRDGERNMEVTPGEKILRNTKEQRDLHNRLREIDEK-------LKMM 392
+L E + K D E EK+ TKE+ DL N+L+ +EK + M+
Sbjct: 537 EKLIEETKRALKSKTDVE--------EKMYSVTKERDDLKNKLKAEEEKGNDLLSRVNML 588
Query: 393 KENVLESTSCLSEEQLKCLLDECILKQKSIIKLSSERKKEDIEDVTPVFPQLSRSIISKL 452
K N L+S + ++ LK L++ K + + + + KE ++V + +L K
Sbjct: 589 K-NRLQSLEAIEKDFLKNKLNQDSGKSTTALHQENNKIKELSQEVERLKLKL------KD 641
Query: 453 LNESETKVQKTEVEDADMLESEECEASKGYYLTKALTGHNMSEALVTEAE 502
+ E + KTE E + E K +L+K L M A AE
Sbjct: 642 MKAIEDDLMKTEDEYETLERRYANERDKAQFLSKELEHVKMELAKYKLAE 691
Score = 50.4 bits (119), Expect = 4e-06
Identities = 84/407 (20%), Positives = 172/407 (42%), Gaps = 36/407 (8%)
Query: 70 DDKQESCSEKIKLAEEGSDEDLDLVQHQIISECSDEPKLKELDSQLQDAIQKMKKLDKIL 129
D ++ +E K+ E+ + ++ +++E S + EL+ + + + M+K D+ +
Sbjct: 134 DIYEKPMNELDKVVEKHKESYRRILGQLLVAEKSRRQTILELEEEKRKHKEYMEKSDEFI 193
Query: 130 AKKQRREKEIKKQGLEMRIKLWEEIKSAKYSEAWQSKEEMENTKKFLSLTAVSEETV--- 186
++ + +KK ++ IK EE + K KEE+ K F + ++ +
Sbjct: 194 CLLEQECERLKKL-IDQEIKSQEEKEQEKEKRVTTLKEELTKLKSFALMVVDEQQRLTAQ 252
Query: 187 ----GPSHEEEDTFSSVFHTQIPPEEYEMQMQKLNKDFTCDVERNESLIKSGKKPFSNTE 242
+E T + HT++ E +Q ++ R E +++ F +
Sbjct: 253 LTLQRQKIQELTTNAKETHTKLALAEARVQEEEQK------ATRLEKELQTQTTKFHQDQ 306
Query: 243 KIELRGKHNQDFIKRNIE--LAKESR--NPVVMVDREKKRLVELLKDLDEKDSGLSSSEG 298
+ N+D R ++ LA SR + + +R ++ E L+D+ EK +S E
Sbjct: 307 DTIMAKLTNEDSQNRQLQQKLAALSRQIDELEETNRSLRKAEEELQDIKEK---ISKGEY 363
Query: 299 DQSGWVVPVKGYELAVTQHQQLAEIDIKLQELSAASPTISSFSPRLENRNNQKPDRDGER 358
+G + V+ EL +++ +++ K +EL + RLE Q D
Sbjct: 364 GNAGIMAEVE--EL----RKRVLDMEGKDEELIKMEEQCRDLNKRLERETLQSKD----F 413
Query: 359 NMEVTPGEKILRNTKEQRDLHNRLREIDEKLKMMKENVLESTSCLSE--EQLKCLLDECI 416
+EV K + ++ D N+ ++ LK E +T LS+ E LK + E
Sbjct: 414 KLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLEKERMTTKQLSQELESLKVRIKELE 473
Query: 417 LKQKSIIKLSSERKKE--DIEDVTPVFPQLSRSIISKLLNESETKVQ 461
+ + K K++ ++ +T +F R +S+ L ++E K+Q
Sbjct: 474 AIESRLEKTEFTLKEDLTKLKTLTVMFVD-ERKTMSEKLKKTEDKLQ 519
Score = 47.0 bits (110), Expect = 5e-05
Identities = 93/540 (17%), Positives = 217/540 (40%), Gaps = 51/540 (9%)
Query: 63 ENRRTSNDDKQESCSEKIKLAEEGSDEDLDLVQHQIISECSDEPKLKELDSQLQDAIQKM 122
E + + + E E I L E+ + L+ +I S+ E + ++ + L++ + K+
Sbjct: 176 EEEKRKHKEYMEKSDEFICLLEQECERLKKLIDQEIKSQEEKEQEKEKRVTTLKEELTKL 235
Query: 123 KKLDKILAKKQRREKEIKKQGLEMRIKLWEEIKSAKYSE---AWQSKEEMENTKKFLSLT 179
K ++ +Q+R + Q R K+ E +AK + A E +K L
Sbjct: 236 KSFALMVVDEQQR---LTAQLTLQRQKIQELTTNAKETHTKLALAEARVQEEEQKATRLE 292
Query: 180 AVSEETVGPSHEEEDT-FSSVFHTQIPPEEYEMQMQKLNKDFTCDVERNESLIKSGKKPF 238
+ H+++DT + + + + + ++ L++ E N SL K+ ++
Sbjct: 293 KELQTQTTKFHQDQDTIMAKLTNEDSQNRQLQQKLAALSRQIDELEETNRSLRKAEEELQ 352
Query: 239 SNTEKIELRGKHNQDFIKRNIELAKESRNPVVMVDREKKRLVELLKDLDEKDSGLSSSEG 298
EKI +G++ I +E ++ + D E ++ E +DL+++ +
Sbjct: 353 DIKEKIS-KGEYGNAGIMAEVEELRKRVLDMEGKDEELIKMEEQCRDLNKRLERETLQSK 411
Query: 299 D-------QSGWVVPVKGYELAVTQHQQ---------------LAEIDIKLQELSAASPT 336
D S ++ ++ E A + +Q ++ +L+ L
Sbjct: 412 DFKLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLEKERMTTKQLSQELESLKVRIKE 471
Query: 337 ISSFSPRLENRN-NQKPDRDGERNMEVTPGEKILRNTKEQRDLHNRLREIDEKLKMMKEN 395
+ + RLE K D + + V ++ +++ + ++L+ +L++ +
Sbjct: 472 LEAIESRLEKTEFTLKEDLTKLKTLTVMFVDERKTMSEKLKKTEDKLQAASSQLQVEQNK 531
Query: 396 VLESTSCLSEEQLKCLLDECILKQKSIIKLSSERKKEDIEDVTPVFPQLSRSIISKLLNE 455
V T L EE + L + +++K S ++++D+++ + ++S+ +N
Sbjct: 532 VTTVTEKLIEETKRALKSKTDVEEK---MYSVTKERDDLKNKLKAEEEKGNDLLSR-VNM 587
Query: 456 SETKVQKTEVEDADMLESEECEASKGYYLTKALTGHNMSEALVTEAENMKC----LQFSK 511
+ ++Q E + D L++ + G T +N + L E E +K ++ +
Sbjct: 588 LKNRLQSLEAIEKDFLKN-KLNQDSGKSTTALHQENNKIKELSQEVERLKLKLKDMKAIE 646
Query: 512 DVIISDTKDYFMSKTLGIGRLKRPSFLDDPLYGISVSLSSEDQHLKLSSPENTIADEQET 571
D ++ +Y + + F LS E +H+K+ + +A++ ET
Sbjct: 647 DDLMKTEDEYETLERRYANERDKAQF-----------LSKELEHVKMELAKYKLAEKTET 695
>gi|109659849 filamin A interacting protein 1-like isoform 2 [Homo
sapiens]
Length = 893
Score = 68.6 bits (166), Expect = 2e-11
Identities = 96/470 (20%), Positives = 197/470 (41%), Gaps = 62/470 (13%)
Query: 51 SGKEDHSESSNTENRRTSNDDKQESCSEKIKLAEEGSDEDLDLVQHQIISECSDEPKLKE 110
+ KE H++ + E R + K ++++ +D D + ++ +E S +L++
Sbjct: 26 NAKETHTKLALAEARVQEEEQKATRLEKELQTQTTKFHQDQDTIMAKLTNEDSQNRQLQQ 85
Query: 111 LDSQLQDAIQKMKKLDKILAKKQRREKEIKKQGLEMRIKLWEEIKSAKYSEAWQSKEEME 170
+ L I ++++ ++ L K + ++IK E+I +Y A E E
Sbjct: 86 KLAALSRQIDELEETNRSLRKAEEELQDIK-----------EKISKGEYGNAGIMAEVEE 134
Query: 171 NTKKFLSLTAVSEETVGPSHEEEDTFSSVFHTQIPPEEYEMQMQKLNKDFTCDVERNESL 230
K+ L + EE + + D + + ++++++++KL+K + ++
Sbjct: 135 LRKRVLDMEGKDEELIKMEEQCRDLNKRLERETLQSKDFKLEVEKLSKRIMALEKLEDAF 194
Query: 231 IKSGKKPFSNTEKIELRGKHNQDFIKRNIELAKESRNPVVMVDREKKRLVELLKDLDEKD 290
KS ++ +S +K N+E + R + +E + L +K+L+ +
Sbjct: 195 NKSKQECYS---------------LKCNLE---KERMTTKQLSQELESLKVRIKELEAIE 236
Query: 291 SGLSSSEGDQSGWVVPVKGYELAV-----TQHQQLAEIDIKLQ----ELSAASPTISSFS 341
S L +E + +K + T ++L + + KLQ +L +++ +
Sbjct: 237 SRLEKTEFTLKEDLTKLKTLTVMFVDERKTMSEKLKKTEDKLQAASSQLQVEQNKVTTVT 296
Query: 342 PRL--ENRNNQKPDRDGERNMEVTPGEKILRNTKEQRDLHNRLREIDEK-------LKMM 392
+L E + K D E EK+ TKE+ DL N+L+ +EK + M+
Sbjct: 297 EKLIEETKRALKSKTDVE--------EKMYSVTKERDDLKNKLKAEEEKGNDLLSRVNML 348
Query: 393 KENVLESTSCLSEEQLKCLLDECILKQKSIIKLSSERKKEDIEDVTPVFPQLSRSIISKL 452
K N L+S + ++ LK L++ K + + + + KE ++V + +L K
Sbjct: 349 K-NRLQSLEAIEKDFLKNKLNQDSGKSTTALHQENNKIKELSQEVERLKLKL------KD 401
Query: 453 LNESETKVQKTEVEDADMLESEECEASKGYYLTKALTGHNMSEALVTEAE 502
+ E + KTE E + E K +L+K L M A AE
Sbjct: 402 MKAIEDDLMKTEDEYETLERRYANERDKAQFLSKELEHVKMELAKYKLAE 451
>gi|109659845 filamin A interacting protein 1-like isoform 1 [Homo
sapiens]
Length = 1135
Score = 68.6 bits (166), Expect = 2e-11
Identities = 96/470 (20%), Positives = 197/470 (41%), Gaps = 62/470 (13%)
Query: 51 SGKEDHSESSNTENRRTSNDDKQESCSEKIKLAEEGSDEDLDLVQHQIISECSDEPKLKE 110
+ KE H++ + E R + K ++++ +D D + ++ +E S +L++
Sbjct: 266 NAKETHTKLALAEARVQEEEQKATRLEKELQTQTTKFHQDQDTIMAKLTNEDSQNRQLQQ 325
Query: 111 LDSQLQDAIQKMKKLDKILAKKQRREKEIKKQGLEMRIKLWEEIKSAKYSEAWQSKEEME 170
+ L I ++++ ++ L K + ++IK E+I +Y A E E
Sbjct: 326 KLAALSRQIDELEETNRSLRKAEEELQDIK-----------EKISKGEYGNAGIMAEVEE 374
Query: 171 NTKKFLSLTAVSEETVGPSHEEEDTFSSVFHTQIPPEEYEMQMQKLNKDFTCDVERNESL 230
K+ L + EE + + D + + ++++++++KL+K + ++
Sbjct: 375 LRKRVLDMEGKDEELIKMEEQCRDLNKRLERETLQSKDFKLEVEKLSKRIMALEKLEDAF 434
Query: 231 IKSGKKPFSNTEKIELRGKHNQDFIKRNIELAKESRNPVVMVDREKKRLVELLKDLDEKD 290
KS ++ +S +K N+E + R + +E + L +K+L+ +
Sbjct: 435 NKSKQECYS---------------LKCNLE---KERMTTKQLSQELESLKVRIKELEAIE 476
Query: 291 SGLSSSEGDQSGWVVPVKGYELAV-----TQHQQLAEIDIKLQ----ELSAASPTISSFS 341
S L +E + +K + T ++L + + KLQ +L +++ +
Sbjct: 477 SRLEKTEFTLKEDLTKLKTLTVMFVDERKTMSEKLKKTEDKLQAASSQLQVEQNKVTTVT 536
Query: 342 PRL--ENRNNQKPDRDGERNMEVTPGEKILRNTKEQRDLHNRLREIDEK-------LKMM 392
+L E + K D E EK+ TKE+ DL N+L+ +EK + M+
Sbjct: 537 EKLIEETKRALKSKTDVE--------EKMYSVTKERDDLKNKLKAEEEKGNDLLSRVNML 588
Query: 393 KENVLESTSCLSEEQLKCLLDECILKQKSIIKLSSERKKEDIEDVTPVFPQLSRSIISKL 452
K N L+S + ++ LK L++ K + + + + KE ++V + +L K
Sbjct: 589 K-NRLQSLEAIEKDFLKNKLNQDSGKSTTALHQENNKIKELSQEVERLKLKL------KD 641
Query: 453 LNESETKVQKTEVEDADMLESEECEASKGYYLTKALTGHNMSEALVTEAE 502
+ E + KTE E + E K +L+K L M A AE
Sbjct: 642 MKAIEDDLMKTEDEYETLERRYANERDKAQFLSKELEHVKMELAKYKLAE 691
Score = 50.4 bits (119), Expect = 4e-06
Identities = 84/407 (20%), Positives = 172/407 (42%), Gaps = 36/407 (8%)
Query: 70 DDKQESCSEKIKLAEEGSDEDLDLVQHQIISECSDEPKLKELDSQLQDAIQKMKKLDKIL 129
D ++ +E K+ E+ + ++ +++E S + EL+ + + + M+K D+ +
Sbjct: 134 DIYEKPMNELDKVVEKHKESYRRILGQLLVAEKSRRQTILELEEEKRKHKEYMEKSDEFI 193
Query: 130 AKKQRREKEIKKQGLEMRIKLWEEIKSAKYSEAWQSKEEMENTKKFLSLTAVSEETV--- 186
++ + +KK ++ IK EE + K KEE+ K F + ++ +
Sbjct: 194 CLLEQECERLKKL-IDQEIKSQEEKEQEKEKRVTTLKEELTKLKSFALMVVDEQQRLTAQ 252
Query: 187 ----GPSHEEEDTFSSVFHTQIPPEEYEMQMQKLNKDFTCDVERNESLIKSGKKPFSNTE 242
+E T + HT++ E +Q ++ R E +++ F +
Sbjct: 253 LTLQRQKIQELTTNAKETHTKLALAEARVQEEEQK------ATRLEKELQTQTTKFHQDQ 306
Query: 243 KIELRGKHNQDFIKRNIE--LAKESR--NPVVMVDREKKRLVELLKDLDEKDSGLSSSEG 298
+ N+D R ++ LA SR + + +R ++ E L+D+ EK +S E
Sbjct: 307 DTIMAKLTNEDSQNRQLQQKLAALSRQIDELEETNRSLRKAEEELQDIKEK---ISKGEY 363
Query: 299 DQSGWVVPVKGYELAVTQHQQLAEIDIKLQELSAASPTISSFSPRLENRNNQKPDRDGER 358
+G + V+ EL +++ +++ K +EL + RLE Q D
Sbjct: 364 GNAGIMAEVE--EL----RKRVLDMEGKDEELIKMEEQCRDLNKRLERETLQSKD----F 413
Query: 359 NMEVTPGEKILRNTKEQRDLHNRLREIDEKLKMMKENVLESTSCLSE--EQLKCLLDECI 416
+EV K + ++ D N+ ++ LK E +T LS+ E LK + E
Sbjct: 414 KLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLEKERMTTKQLSQELESLKVRIKELE 473
Query: 417 LKQKSIIKLSSERKKE--DIEDVTPVFPQLSRSIISKLLNESETKVQ 461
+ + K K++ ++ +T +F R +S+ L ++E K+Q
Sbjct: 474 AIESRLEKTEFTLKEDLTKLKTLTVMFVD-ERKTMSEKLKKTEDKLQ 519
Score = 47.0 bits (110), Expect = 5e-05
Identities = 93/540 (17%), Positives = 217/540 (40%), Gaps = 51/540 (9%)
Query: 63 ENRRTSNDDKQESCSEKIKLAEEGSDEDLDLVQHQIISECSDEPKLKELDSQLQDAIQKM 122
E + + + E E I L E+ + L+ +I S+ E + ++ + L++ + K+
Sbjct: 176 EEEKRKHKEYMEKSDEFICLLEQECERLKKLIDQEIKSQEEKEQEKEKRVTTLKEELTKL 235
Query: 123 KKLDKILAKKQRREKEIKKQGLEMRIKLWEEIKSAKYSE---AWQSKEEMENTKKFLSLT 179
K ++ +Q+R + Q R K+ E +AK + A E +K L
Sbjct: 236 KSFALMVVDEQQR---LTAQLTLQRQKIQELTTNAKETHTKLALAEARVQEEEQKATRLE 292
Query: 180 AVSEETVGPSHEEEDT-FSSVFHTQIPPEEYEMQMQKLNKDFTCDVERNESLIKSGKKPF 238
+ H+++DT + + + + + ++ L++ E N SL K+ ++
Sbjct: 293 KELQTQTTKFHQDQDTIMAKLTNEDSQNRQLQQKLAALSRQIDELEETNRSLRKAEEELQ 352
Query: 239 SNTEKIELRGKHNQDFIKRNIELAKESRNPVVMVDREKKRLVELLKDLDEKDSGLSSSEG 298
EKI +G++ I +E ++ + D E ++ E +DL+++ +
Sbjct: 353 DIKEKIS-KGEYGNAGIMAEVEELRKRVLDMEGKDEELIKMEEQCRDLNKRLERETLQSK 411
Query: 299 D-------QSGWVVPVKGYELAVTQHQQ---------------LAEIDIKLQELSAASPT 336
D S ++ ++ E A + +Q ++ +L+ L
Sbjct: 412 DFKLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLEKERMTTKQLSQELESLKVRIKE 471
Query: 337 ISSFSPRLENRN-NQKPDRDGERNMEVTPGEKILRNTKEQRDLHNRLREIDEKLKMMKEN 395
+ + RLE K D + + V ++ +++ + ++L+ +L++ +
Sbjct: 472 LEAIESRLEKTEFTLKEDLTKLKTLTVMFVDERKTMSEKLKKTEDKLQAASSQLQVEQNK 531
Query: 396 VLESTSCLSEEQLKCLLDECILKQKSIIKLSSERKKEDIEDVTPVFPQLSRSIISKLLNE 455
V T L EE + L + +++K S ++++D+++ + ++S+ +N
Sbjct: 532 VTTVTEKLIEETKRALKSKTDVEEK---MYSVTKERDDLKNKLKAEEEKGNDLLSR-VNM 587
Query: 456 SETKVQKTEVEDADMLESEECEASKGYYLTKALTGHNMSEALVTEAENMKC----LQFSK 511
+ ++Q E + D L++ + G T +N + L E E +K ++ +
Sbjct: 588 LKNRLQSLEAIEKDFLKN-KLNQDSGKSTTALHQENNKIKELSQEVERLKLKLKDMKAIE 646
Query: 512 DVIISDTKDYFMSKTLGIGRLKRPSFLDDPLYGISVSLSSEDQHLKLSSPENTIADEQET 571
D ++ +Y + + F LS E +H+K+ + +A++ ET
Sbjct: 647 DDLMKTEDEYETLERRYANERDKAQF-----------LSKELEHVKMELAKYKLAEKTET 695
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 62.0 bits (149), Expect = 1e-09
Identities = 115/566 (20%), Positives = 237/566 (41%), Gaps = 64/566 (11%)
Query: 49 LNSGKEDHSESSNTENRRTSNDDKQESCSEKIKLAEEGSDEDLDLVQHQIISECSDEPKL 108
+N +++ S+ + ND Q E + E+ + + + VQ ++ +
Sbjct: 1498 VNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHR 1557
Query: 109 KELDSQLQDAIQKMKKLDKILAKKQR------REKEIKKQGLEMRIKLWEEIKSAKYSEA 162
K DS LQ KM +L L + Q +EKE K+ E +++K
Sbjct: 1558 KAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKENTKEIV 1617
Query: 163 WQSKEEMENTKKFLSLTAVSEETVGPSHEEEDTFSSVFHTQIPPEEYEMQMQKL---NKD 219
+ KE E +FL +TAV +E ++ + H + E ++ ++ + N
Sbjct: 1618 AKMKESQEKEYQFLKMTAV--------NETQEKMCEIEHLKEQFETQKLNLENIETENIR 1669
Query: 220 FTCDVERNESLIKSGKKPFSNTEKIELRGKHNQDFIKRNI------ELAKESRNPVV-MV 272
T + N ++S K + +E K +D +K N+ +L K+ +V M
Sbjct: 1670 LTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIVHMH 1729
Query: 273 DREKKRLVELLKDL-DEKDSGLSSSEGDQSGWVVPVKGYELAVTQHQQLAEIDIKLQE-- 329
+E + ++ L+ + EK + +S+ + D +K +L + + ++A + +K Q+
Sbjct: 1730 LKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQET 1789
Query: 330 -------LSAASPTISSFSPRLENRNNQKPDRDGERNMEVTPGEKILRNTKEQRDLHNRL 382
+S + +S+ LEN N + E+ E+ E L K +D++
Sbjct: 1790 IDKLRGIVSEKTDKLSNMQKDLENSNAKLQ----EKIQELKANEHQLITLK--KDVNETQ 1843
Query: 383 REIDEKLKMMKENVLESTSCLSEEQLKCL-----LDECILKQKSIIKLSSERKKEDIEDV 437
+++ E ++ +K+ + + + LS+ +++ L L E + + KS++K +++++ V
Sbjct: 1844 KKVSE-MEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMK-----ERDNLRRV 1897
Query: 438 TPVFPQLSRSIISKLLNESETK---VQKTEVEDADMLESEECEASKGYYLTKALTGHNMS 494
+L R + + L E++ + +Q+ E++ A ML E E T +S
Sbjct: 1898 EETL-KLERDQLKESLQETKARDLEIQQ-ELKTARMLSKEHKE-------TVDKLREKIS 1948
Query: 495 EALVTEAENMKCLQFSKDVIISDTKDYFMSKTLGIGRLKRPSFLDDPLYGISVSLSSEDQ 554
E + ++ K L SKD + ++ K L + R+K + L + +
Sbjct: 1949 EKTIQISDIQKDLDKSKDELQKKIQE-LQKKELQLLRVKEDVNMSHKKINEMEQLKKQFE 2007
Query: 555 HLKLSSPENTIADEQETKDAAEECKE 580
LS + + Q TK E +E
Sbjct: 2008 AQNLSMQSVRMDNFQLTKKLHESLEE 2033
Score = 44.7 bits (104), Expect = 2e-04
Identities = 97/517 (18%), Positives = 212/517 (41%), Gaps = 63/517 (12%)
Query: 78 EKIKLAEEGSDEDLDLVQHQIISECSDEPKLKELDSQLQDAIQKMKKLDKILAKKQRREK 137
E+++L + + ++V + E +L +L + +K+K+ + L +KQ++
Sbjct: 1085 EELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLL 1144
Query: 138 EIKKQGLEMRIKLWEEIKSAKYSEAWQSKEEMENTKKFLSLTAVSEETVGPSHEEEDTFS 197
++++ EM+ K+ E E ++N K LT ET
Sbjct: 1145 NVQEEMSEMQKKINE-------------IENLKNELKNKELTLEHMET------------ 1179
Query: 198 SVFHTQIPPEEYEMQMQKLNKDF--TCDVERNESLIKSGKKPFSNTEKIELRGKHNQDFI 255
E E+ QKLN+++ + + ++K +K F TE+ LRG + ++
Sbjct: 1180 ---------ERLEL-AQKLNENYEEVKSITKERKVLKELQKSF-ETERDHLRG-YIREIE 1227
Query: 256 KRNIELAKESRNPVVMVDREKKRLVELLKDLDEKDSGLSSSEGDQSGWV-----VPVKGY 310
++ +E + + + ++ + EL + + EK + + +++ + +PV
Sbjct: 1228 ATGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHE 1287
Query: 311 ELAVTQH-QQLAEIDIKLQELSAASPTISSFSPRLENRNNQKPDRDGERNMEVTPGEKIL 369
E + + ++++E + EL + ++ R + R E+ E E+I
Sbjct: 1288 EQELLPNVKEVSETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQE--SQEEIK 1345
Query: 370 RNTKEQRDLHNRLREIDEKLKMMKENVLESTSCLSEEQLKCLLDECIL----KQKSIIKL 425
TKE+ +L ++ K +KE++ E+ + + E Q K E L K K+
Sbjct: 1346 SLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSK---QEQSLNMKEKDNETTKI 1402
Query: 426 SSERKKEDIEDVTPVFPQLSRSIISKLLNESETKVQKTEVEDADMLESEECEASKGYYLT 485
SE ++ +D + ++ +SK L ES +++ E D+ +E S+ L
Sbjct: 1403 VSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLK 1462
Query: 486 KALTGHNMSEALVTEAE--NMKCLQFSKDVIISDTKDYFMSKTLGIGRLKRPSFLDDPLY 543
+ + +++ L TE E C ++ I++ + K I +++ L
Sbjct: 1463 ENIK-EIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQK------QLE 1515
Query: 544 GISVSLSSEDQHLKLSSPENTIADEQETKDAAEECKE 580
I+ L ++ Q + + I E ++ E K+
Sbjct: 1516 AINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQ 1552
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 58.9 bits (141), Expect = 1e-08
Identities = 118/569 (20%), Positives = 224/569 (39%), Gaps = 103/569 (18%)
Query: 63 ENRRTSNDDKQESCSEKIKLAEEGSDEDLDLVQHQIISECSD-------EPKLKELDSQL 115
+ + T DK+ I+ E + E LD+ Q ++ S S+ KL+E S L
Sbjct: 651 QEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVL 710
Query: 116 QDAIQKMKK----------------LDKILAKK----QRREKEIKKQGLEMRIKLWEEIK 155
+D KMK+ +D I+ + QR EK +K Q ++ + L E K
Sbjct: 711 KDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDK 770
Query: 156 SAKYSEAWQSKEEMENTKKFLSLTAVSEETVGPSHEEEDTFSSVFHTQIPPEEYEMQMQK 215
K +A +EN + + + + + ++ S H Q + YE Q+ +
Sbjct: 771 HLKEHQA-----HVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQT--KAYEEQLAQ 823
Query: 216 LNKDFTCDVERNESLIKSGKKPFSNTEKIELRGKHNQDFIKRNIELAKESRNPVVMVDRE 275
L + D+E TE+I L K+ E+ + ++ +D
Sbjct: 824 LQQKLL-DLE---------------TERILLT--------KQVAEVEAQKKDVCTELDAH 859
Query: 276 KKRLVELLKDLDEKDSGLS-----------------SSEGDQSGWVVPVKGYELAVTQHQ 318
K ++ +L++ L++++S + + E +Q+ ++ K + +
Sbjct: 860 KIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREG 919
Query: 319 QLAEIDIKLQELSAASPTISSFSPRLENR-NNQKPD----RDGERNMEVTPGEKIL-RNT 372
Q EI+I Q+LSA +I + E + NQ+ + + M+ T +K+L +
Sbjct: 920 QKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEA 979
Query: 373 KEQRDLHNRLREIDEKLKMMKENVLESTSCLSEEQLKCLLDECILKQKSIIKLSSERKKE 432
K +++L N E+ +K K +LE S + + + + ++ +KE
Sbjct: 980 KLKKELENTALELSQKEKQFNAKMLEMAQANSAG-----ISDAVSRLET-------NQKE 1027
Query: 433 DIEDVTPVFPQLSRSIISKLLNESETKVQKTEVEDADMLESEECEASKGYYLTKALTGHN 492
IE +T V + +IS + E + Q E+++ ++ +E E K L
Sbjct: 1028 QIESLTEVHRRELNDVIS--IWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGC 1085
Query: 493 MSEALVTEAENMKCLQFSKDVIISDTKDYFMSKTLGIGRLKRPSFLDDPLYGISVSLSSE 552
E + E +K +D +++ ++ K+ + L + + L
Sbjct: 1086 EKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDE------TKLKAHLEKL 1139
Query: 553 DQHLKLSSPENTIADEQ--ETKDAAEECK 579
+ L S ENT EQ E K AEE K
Sbjct: 1140 EVDLNKSLKENTFLQEQLVELKMLAEEDK 1168
Score = 55.8 bits (133), Expect = 1e-07
Identities = 97/495 (19%), Positives = 199/495 (40%), Gaps = 82/495 (16%)
Query: 77 SEKIKLAEEGSDEDLDLVQHQIISECSDEPKLKELDSQLQDA------------IQKMKK 124
S K L S E L+ + + D P ++DS+ +D IQ++++
Sbjct: 88 SSKESLVRTSSRESLNRLDLDSSTASFDPPS--DMDSEAEDLVGNSDSLNKEQLIQRLRR 145
Query: 125 LDKILAKKQRREKEI---------KKQGLEMRIKLWEEIKSAKYSEAWQSKEEMENTKKF 175
+++ L+ + + E+ +K+ L+ + ++ + +E + + + KK
Sbjct: 146 MERSLSSYRGKYSELVTAYQMLQREKKKLQGILSQSQDKSLRRIAELREELQMDQQAKKH 205
Query: 176 LSLTAVSEETVGPSHEEEDTFSSVFHTQI------------------PPEEYEMQMQKLN 217
L +E S EE+D + SV TQ+ P + E Q +
Sbjct: 206 L------QEEFDASLEEKDQYISVLQTQVSLLKQRLRNGPMNVDVLKPLPQLEPQAEVFT 259
Query: 218 KDFTCDVERNESLIKSGKKPFSNTEKIELRGKHNQDFIKRNIELAKESRNPVVMVDREKK 277
K+ + + E +++ G E ++ R K ++ +KR E + + ++ EK+
Sbjct: 260 KEENPESD-GEPVVEDGTS-VKTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKE 317
Query: 278 RL----------VELLKDLD-EKDSGLSSSEGDQSGWVVPV---KGYELAVTQHQQLAEI 323
L +E +KDL + + L + D + + KG +A T+ Q +
Sbjct: 318 ALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETL 377
Query: 324 DIKLQELSAASPTISSFSPRLENRNNQKPDRDGERNMEVTPGEKILRNTKEQRDLHNRLR 383
++K +E++ I + + E QK + E+ EK L ++ + +L+
Sbjct: 378 EMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEEL---EKALSTAQKTEEARRKLK 434
Query: 384 -EIDEKLKMMKENVLESTSCLSEE----------QLKCLLDECILKQKSIIKLSSERKKE 432
E+DE++K +++ E L +E +K +E I K + + + RK++
Sbjct: 435 AEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQ 494
Query: 433 DIEDVTPVFPQLSRSIISKLLNESETKVQK--TEVEDADMLESEECEASKGYYLTKALTG 490
++ + + + L +S+++ K E E + L EE E K LT++
Sbjct: 495 ELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTES--- 551
Query: 491 HNMSEALVTEAENMK 505
N L EAE +
Sbjct: 552 ENKLRDLQQEAETYR 566
Score = 48.9 bits (115), Expect = 1e-05
Identities = 81/441 (18%), Positives = 183/441 (41%), Gaps = 50/441 (11%)
Query: 72 KQESCSEKIKLAEEGSDEDLDLVQHQIISECSDEPKLKELDSQLQDAIQKMKKLDKILAK 131
K E +K K+ ++ S+ + +L S ++ EL+ + +++ L+++L K
Sbjct: 1499 KGEMEDDKSKMEKKESNLETELK--------SQTARIMELEDHITQKTIEIESLNEVL-K 1549
Query: 132 KQRREKEIKKQGLEMRIKLWEEIKSAK--------------YSEAWQSKEEMENTKKFL- 176
++K+I+ + L +++ ++E+ K ++ + K E+E KK L
Sbjct: 1550 NYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELE 1609
Query: 177 --SLTAVSEETVGPSHEEEDTFSSVFHTQIPPEEYEMQMQKLNKDFTCDVERNESLIKSG 234
+L+ S+E + E+ S + E ++ + K +E E K G
Sbjct: 1610 HVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKG 1669
Query: 235 KKPFSNTEKIELRGKHNQ-DFIKRNIELAKESRNPVVMVDREKKRLVE------------ 281
+ + +L+ + + ++ ++ + S++ ++V R K +
Sbjct: 1670 TESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGC 1729
Query: 282 LLKDLDEKDSGLSSSEGDQSGWVVPV-KGYELAVTQHQQLA----EIDIKLQELSAASPT 336
+ K +EK S L + ++ + V + E V+ H ++ E IKL+ A
Sbjct: 1730 VQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHE 1789
Query: 337 ISSFSPRLENRNNQKPDRDGERNMEVTPGEKILRNTKEQRDLHNRLREIDEKLKMMKENV 396
S L+ +K + + E N + +++L N D+ K ++E
Sbjct: 1790 DQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLEN---VFDDVQKTLQEK- 1845
Query: 397 LESTSCLSEEQLKCLLDECILKQKSIIKLSSERKKEDIEDVTPVFPQLSRSIISKLLNES 456
E T + E+++K LD C+++QK + ++ E E + + R+ ++LL E+
Sbjct: 1846 -ELTCQILEQKIK-ELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELLEEN 1903
Query: 457 ETKVQKTEVEDADMLESEECE 477
+ K+ + +L + E +
Sbjct: 1904 TEEKSKSHLVQPKLLSNMEAQ 1924
Score = 45.4 bits (106), Expect = 1e-04
Identities = 91/492 (18%), Positives = 201/492 (40%), Gaps = 91/492 (18%)
Query: 54 EDHSESSNTENRRTSNDDKQESCSEKIKLAEEGSDEDLDLVQHQIISECSDEPKLKELDS 113
E E N E +T ++ I EG ++++++ ++ ++ E + L+
Sbjct: 889 ESKLEDGNKEQEQTKQILVEKE--NMILQMREGQKKEIEILTQKLSAK---EDSIHILNE 943
Query: 114 QLQDAIQKM-KKLDKILAKKQRREKEIKKQGLEMRIKLWEEIK-------------SAKY 159
+ + + KK++K+ K + ++ +KK+ L+ KL +E++ +AK
Sbjct: 944 EYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKM 1003
Query: 160 SEAWQ----------SKEEMENTKKFLSLTAVSEETVG--------PSHEEEDTFSSVFH 201
E Q S+ E ++ SLT V + +++ + +
Sbjct: 1004 LEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHE 1063
Query: 202 TQIPPEEYEM------------QMQKLNKDFTC--------DVERNE------------- 228
Q+ +E E+ + +++NK+ T D NE
Sbjct: 1064 IQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVN 1123
Query: 229 SLIKSGKKPFSNTEKIELRGKHNQDFIKRNIELAKESRNPVVMVDREKKRLVEL---LKD 285
SL + K ++ EK+E+ + +K N L ++ ++ + +K+++ EL LK
Sbjct: 1124 SLAQDETKLKAHLEKLEVDLNKS---LKENTFLQEQLVELKMLAEEDKRKVSELTSKLKT 1180
Query: 286 LDEKDSGLSSSEGDQSGWVVPVKGYELAVTQHQQLAEIDIKLQE----LSAASPTISSFS 341
DE+ L SS ++S + K E + ++DI ++ L A + + + S
Sbjct: 1181 TDEEFQSLKSSH-EKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKTNELINIS 1239
Query: 342 PRLENRNNQKPDRDGERNMEVTPGEKILRNTKEQRDLHNRLREIDEKLKMMKENVLESTS 401
N + R +V E +L T +L +LR++ E+ + + ++T
Sbjct: 1240 SSKTNAILSRISHCQHRTTKVK--EALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATH 1297
Query: 402 CLSEEQ-----LKCLLDECILKQKSIIKLSSERKKEDIED---VTPVFPQLSRSIISKLL 453
L E++ +K ++ + +++++ K +++ E +T + +LS +I + L
Sbjct: 1298 QLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTL 1357
Query: 454 NESETKVQKTEV 465
+ E K +K E+
Sbjct: 1358 MKEELKEKKVEI 1369
Score = 33.1 bits (74), Expect = 0.72
Identities = 43/200 (21%), Positives = 88/200 (44%), Gaps = 21/200 (10%)
Query: 49 LNSGKEDHSESSNTENRRTSNDDKQESC---------SEKIKLAEE--GSDEDLDLV--Q 95
L E+ S+S + + SN + Q + EK KL +E +DL ++ +
Sbjct: 1900 LEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKE 1959
Query: 96 HQ----IISECSDEPKLKELDSQLQDAIQKMKKLDKILAKKQRREKEIKKQGLEMRIKLW 151
HQ I+ + D+ + +++ + +D K K L ++ + K+Q LEM IK
Sbjct: 1960 HQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIK-- 2017
Query: 152 EEIKSAKYSEAWQSKEEMENTKKFLSLTAVSEETVGPSHEEEDTFSSVFHTQIPPE--EY 209
E I A+ EA + E T + L A ++ + + + + ++ + +
Sbjct: 2018 ETINKAQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDL 2077
Query: 210 EMQMQKLNKDFTCDVERNES 229
+ Q+++L K + +E+ E+
Sbjct: 2078 QTQLEELQKKYQQKLEQEEN 2097
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 58.5 bits (140), Expect = 2e-08
Identities = 78/397 (19%), Positives = 173/397 (43%), Gaps = 36/397 (9%)
Query: 63 ENRRTSNDDKQESCSEKIKLAEEGSDEDLDLVQHQIISECSDEPKLKELDSQL------Q 116
E + ++ EK++ EE E + ++ Q E K++EL+ ++ +
Sbjct: 348 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIR 407
Query: 117 DAIQKMKKLDKILAKKQRREKEIKKQGLEMRIKLWEEIKSAKYSEAWQSKEEMENTKKFL 176
+ +K ++ +KI +++R+E+E K E +I+ EE + + W+ +E++ +K
Sbjct: 408 EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIR 467
Query: 177 SLTAVSEE-----TVGPSHEEEDTFSSVFHTQIPPEEYEMQMQKLNKDFTCDVERNESLI 231
E+ HE+E+ + E+ Q +K+ + E+ E +
Sbjct: 468 EEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIR 527
Query: 232 KSGKKPFSNTEKI--------ELRGKHNQDFI----KRNIELAKESRNPVVMVDREKK-- 277
+ +K + EKI E H Q+ I KR + K R + ++E+K
Sbjct: 528 EQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVW 587
Query: 278 RLVELLKDLDEKDSGLSSSEGDQSGWVVPVKGYELAVTQHQQLAEIDIKLQELSAASPTI 337
R E +++ +EK E ++ W K E Q +++ E + K++E
Sbjct: 588 RQEEKIREQEEK-----RQEQEEKMW----KQEEKIREQEEKIQEQEEKIREQEEKIREQ 638
Query: 338 SSFSPRLENRNNQKPDRDGERNMEVTPGEKIL-RNTKEQRDLHNRLREIDEKLKMMKENV 396
+ E + ++ ++ E+ ++ E+ + R ++ R+ ++RE +EK++ +E +
Sbjct: 639 EEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMM 698
Query: 397 LESTSCLSEEQLK-CLLDECILKQKSIIKLSSERKKE 432
E + E++ K C +E + +Q+ ++ E+ E
Sbjct: 699 QEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWE 735
Score = 49.7 bits (117), Expect = 7e-06
Identities = 79/422 (18%), Positives = 174/422 (41%), Gaps = 48/422 (11%)
Query: 70 DDKQESCSEKIKLAEEGSDEDLDLVQHQIISECSDEPKLKELDSQLQDAIQKMKKLDKIL 129
++K + EKI+ EE E + ++ Q E K++ + + + +KM++ ++++
Sbjct: 313 EEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMM 372
Query: 130 AKKQ---RREKEI----KKQGLEMRIKLWEEIKSAKYSEAWQSKEEMENTKKFLSLTAVS 182
+K+ RR++E+ +++ E+ K+ E+ K + E Q +E++ +K A
Sbjct: 373 WEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKM 432
Query: 183 EETVGPSHEEEDTFSSVFHTQIPPEEYEMQMQKLNKDFTCDVERNESLIKSGKKPFSNTE 242
E+E+ EE + +K+ R E + ++ + E
Sbjct: 433 WRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKI---------REEEKRQEQEEMWRQEE 483
Query: 243 KIELRGKHNQDFIKRNIELAKESRNPVVMVDREKKRLVELLKDLDEKDSGLSSSEGDQSG 302
KI H Q+ I R E E + + + R E +++ +EK E ++
Sbjct: 484 KI-----HEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEK-----IREQEEKM 533
Query: 303 WVVPVKGYELAVTQHQQLAEIDIKLQELSAASPTISSFSPRLENRNNQKPDRDGERNMEV 362
W E + + +++ + K+ E I R E + + R E
Sbjct: 534 W-----RQEEKIREQEEMWREEEKMHE----QEKIWEEEKRQEQEDKMWRQEEKIREQE- 583
Query: 363 TPGEKILRNTKEQRDLHNRLREIDEKLKMMKENVLESTSCLSEEQLKCL-LDECILKQKS 421
EK+ R ++ R+ + +E +EK+ +E + E + E++ K +E I +Q+
Sbjct: 584 ---EKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEE 640
Query: 422 IIKLSSERKKEDIEDVTPVFPQLSRSIIS-----KLLNESETKVQKTEV---EDADMLES 473
+ + E+ E E + ++ + + + E E K+++ E E +M++
Sbjct: 641 MTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQE 700
Query: 474 EE 475
+E
Sbjct: 701 QE 702
Score = 35.8 bits (81), Expect = 0.11
Identities = 42/231 (18%), Positives = 99/231 (42%), Gaps = 4/231 (1%)
Query: 249 KHNQDFIKRNIELAKESRNPVVMVDREKKRLVELLKDLDEKDSGLSSSEGDQSGWVVPVK 308
++ ++ K L+ E + + K++ +L + L +S S + + ++
Sbjct: 193 RYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLE 252
Query: 309 GYELAVTQHQQLAEIDIKLQELSAASPTISSFSPRLE--NRNNQKPDRDGERNMEVTPG- 365
+L + Q Q AE D +EL + S + + E NR NQ+ + R E
Sbjct: 253 RAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEW 312
Query: 366 -EKILRNTKEQRDLHNRLREIDEKLKMMKENVLESTSCLSEEQLKCLLDECILKQKSIIK 424
EKI ++ R+ ++RE +EK++ +E + E + ++ E ++++ +
Sbjct: 313 EEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMM 372
Query: 425 LSSERKKEDIEDVTPVFPQLSRSIISKLLNESETKVQKTEVEDADMLESEE 475
E K E++ + R + K+ + + + Q+ + ++ + + +E
Sbjct: 373 WEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE 423
Score = 34.3 bits (77), Expect = 0.32
Identities = 21/113 (18%), Positives = 53/113 (46%), Gaps = 1/113 (0%)
Query: 53 KEDHSESSNTENRRTSNDDKQESCSEKIKLAEEGSDEDLDLVQHQIISECSDEPKLKELD 112
+E + E + ++K EK++ EE + ++ Q E K++E +
Sbjct: 636 REQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQE 695
Query: 113 SQLQDAIQKMKKLDKILAKKQRREKEIKKQGLEMRIKLWE-EIKSAKYSEAWQ 164
+Q+ +KM + ++ + +++ + +E +++ K+WE E++ + E Q
Sbjct: 696 EMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 748
>gi|41872583 Rho-associated, coiled-coil containing protein kinase 2
[Homo sapiens]
Length = 1388
Score = 56.2 bits (134), Expect = 8e-08
Identities = 80/428 (18%), Positives = 193/428 (45%), Gaps = 33/428 (7%)
Query: 55 DHSESSNTENRRTSNDDKQESCSEKIKLAEEGSDEDLDLVQHQIISEC-SDEPKLKELDS 113
D T++ ++ +++ + +K+ EE ++ + ++ +C S +L++
Sbjct: 424 DSPSCRETDSIQSRKNEESQEIQKKLYTLEEHLSNEMQ-AKEELEQKCKSVNTRLEKTAK 482
Query: 114 QLQDAIQKMKKLDKILAKKQRREKEIKKQGLEMRIKLWEEIKSAKYSE--AWQSKEEMEN 171
+L++ I K ++ L + +R + ++ + E + K E + E K+++E+
Sbjct: 483 ELEEEITLRKSVESALRQLEREKALLQHKNAEYQRKADHEADKKRNLENDVNSLKDQLED 542
Query: 172 TKKFLSLTAVSEETVGPSHEEEDTFSSVFHTQIPPEEYEMQMQKLNKDFTCDVERNESLI 231
KK + +S E V + D +++ T+ + +++K + + +++ ES
Sbjct: 543 LKKRNQNSQISTEKVNQLQRQLDETNALLRTE---SDTAARLRKTQAESSKQIQQLESNN 599
Query: 232 KS--GKKPFSNTEKIELRGKHNQDFIKRNIELAKESRNPVVMVDREKKRLVELLKDLDEK 289
+ K T K++L ++FI N++ A ES R++ E++ DL +
Sbjct: 600 RDLQDKNCLLETAKLKLE----KEFI--NLQSALESER------RDRTHGSEIINDLQGR 647
Query: 290 DSGLSSSEGDQSGWVVPVKGYELAVTQHQQLAEIDIKLQELSAASPTISSFSPRLENRNN 349
GL E D + + EL + +QL E L++ + ++ ++ ++
Sbjct: 648 ICGL---EEDLKNGKILLAKVEL---EKRQLQERFTDLEKEKSNMEIDMTYQLKVIQQSL 701
Query: 350 QKPDRDGERNM-EVTPGEKILRNTKEQRDLHNRLREIDEKLKMMKENVLESTSCLSEEQL 408
++ + + + + KI + +E + ++E+++KL + + + L E +
Sbjct: 702 EQEEAEHKATKARLADKNKIYESIEEAKS--EAMKEMEKKLLEERTLKQKVENLLLEAEK 759
Query: 409 KCLLDECILKQKSIIKLSSERKKEDI--EDVTPVFPQLSRSIISKLLNESETKVQKTEVE 466
+C L +C LKQ S K++ K++D+ EDV + ++ + + L +++ K+Q +V
Sbjct: 760 RCSLLDCDLKQ-SQQKINELLKQKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVN 818
Query: 467 DADMLESE 474
M E +
Sbjct: 819 TLKMSEKQ 826
Score = 47.4 bits (111), Expect = 4e-05
Identities = 86/379 (22%), Positives = 159/379 (41%), Gaps = 73/379 (19%)
Query: 67 TSNDDKQESCS-EKIKLAEEGSDEDLDLVQHQIISECSDEPKLKELDSQLQDAIQKMKKL 125
T ND K ++ +K++E+ ++ + H + + + E + EL + QDA +MK+L
Sbjct: 806 TQNDLKMQTQQVNTLKMSEKQLKQENN---HLMEMKMNLEKQNAELRKERQDADGQMKEL 862
Query: 126 DKILAKKQRREKEIKKQGLEMRIKLWEEIKSAKYSEAWQSKEEMENTKKFLSLTAVSEET 185
L +Q K Q E++ + E+ K K E Q K+E+++ + SL A E T
Sbjct: 863 QDQLEAEQYFSTLYKTQVRELKEECEEKTKLGK--ELQQKKQELQDERD--SLAAQLEIT 918
Query: 186 VGPSHEEEDTFSSVFHTQIPPEEY-EMQMQKLNKDFTCDVERNESLIKSGKKPFSNTEKI 244
+ + E+ I E+Y +++ +K+ K+ E
Sbjct: 919 LTKADSEQ------LARSIAEEQYSDLEKEKIMKEL---------------------EIK 951
Query: 245 ELRGKHNQDFIKRNIELAK-ESRNPVVMVD-----REKKRLVELLKDLDEKDSGLSSSEG 298
E+ +H Q+ +++ +A E N + D EK+ L LKD+ E+ S L E
Sbjct: 952 EMMARHKQELTEKDATIASLEETNRTLTSDVANLANEKEELNNKLKDVQEQLSRLKDEEI 1011
Query: 299 DQSGWVVPVKGYELAVTQHQQLAEIDIKLQELSAASPTISSFSPRLENRNNQKPDRDGER 358
+ +K A + Q L E +K Q ++ + E N ++P + G
Sbjct: 1012 SAAA----IK----AQFEKQLLTERTLKTQAVNKLA----------EIMNRKEPVKRGN- 1052
Query: 359 NMEVTPGEKILRNTKEQRDLHNRLREIDEKLKMMKENVLESTSCLSEEQLKCLLDECILK 418
+ R KE R LH L+ EKL + +++ L+E Q + + I
Sbjct: 1053 ------DTDVRRKEKENRKLHMELKSEREKL---TQQMIKYQKELNEMQAQIAEESQI-- 1101
Query: 419 QKSIIKLSSERKKEDIEDV 437
+ ++++ + K DIE +
Sbjct: 1102 -RIELQMTLDSKDSDIEQL 1119
Score = 34.3 bits (77), Expect = 0.32
Identities = 51/249 (20%), Positives = 96/249 (38%), Gaps = 30/249 (12%)
Query: 66 RTSNDDKQESCSEKIKLAEEGSDEDLDLVQHQIISECSDEPKLKELDSQLQDAIQKMKKL 125
+T + +E C EK KL +E + +L + E L + DS+ +L
Sbjct: 877 KTQVRELKEECEEKTKLGKELQQKKQELQDERDSLAAQLEITLTKADSE---------QL 927
Query: 126 DKILAKKQRREKEIKKQGLEMRIKLWEEIKSAKYSEAWQSKEEMENTKKFL-----SLTA 180
+ +A++Q + E +K E+ IK + +E + +E T + L +L
Sbjct: 928 ARSIAEEQYSDLEKEKIMKELEIKEMMARHKQELTEKDATIASLEETNRTLTSDVANLAN 987
Query: 181 VSEETVGPSHEEEDTFSSVFHTQIPPEEYEMQMQK-LNKDFTCDVERNESL--IKSGKKP 237
EE + ++ S + +I + Q +K L + T + L I + K+P
Sbjct: 988 EKEELNNKLKDVQEQLSRLKDEEISAAAIKAQFEKQLLTERTLKTQAVNKLAEIMNRKEP 1047
Query: 238 FSNTEKIELRGKHNQD-------------FIKRNIELAKESRNPVVMVDREKKRLVELLK 284
++R K ++ ++ I+ KE + E + +EL
Sbjct: 1048 VKRGNDTDVRRKEKENRKLHMELKSEREKLTQQMIKYQKELNEMQAQIAEESQIRIELQM 1107
Query: 285 DLDEKDSGL 293
LD KDS +
Sbjct: 1108 TLDSKDSDI 1116
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 56.2 bits (134), Expect = 8e-08
Identities = 71/369 (19%), Positives = 168/369 (45%), Gaps = 25/369 (6%)
Query: 53 KEDHSESSNTENRRTSNDDKQESCSEKIKLAEEGSDEDLDLVQHQIISECSDEPKLKELD 112
+E + + E R D++ E+++ E+ +++ + + + I E E K++E +
Sbjct: 348 REQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIRE--REKKMREEE 405
Query: 113 SQLQDAIQKMKKLDKILAKKQRREKEIKKQGL-EMRIKLWEEIKSAKYSEA-WQSKEEME 170
+++ +KM+K ++ + +++ EKE ++Q L E + KLWE+ K + E W+ +E++
Sbjct: 406 ETMREQEEKMQKQEENMWEQE--EKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIR 463
Query: 171 NTKKFLSLTAVSEETVGPSHEEEDTFSSVFHTQIPPEEYEMQMQKLNKDFTCDVER---N 227
+ ++ E+ + + + ++ + + E +M + ER
Sbjct: 464 DQEEMWG----QEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREK 519
Query: 228 ESLIKSGKKPFSNTEKIELRGKHNQDFIKRNIELAKESRNPVVMVDREKKRLVE--LLKD 285
E ++ KK + EK+ K Q+ K+ + ++ R M +REKK E ++++
Sbjct: 520 EERMREQKKMWQQEEKMR-EEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMRE 578
Query: 286 LDEK--DSGLSSSEGDQSGWVVPVKGYELAVTQHQQLAEIDIKL--QELSAASPTISSFS 341
+EK + E ++ W K E Q +++ E + K+ QE
Sbjct: 579 QEEKMQEQEEKMREQEEKMWEQEEKMQE----QEEKMWEQEEKMWEQEEEDKMQEQEEMM 634
Query: 342 PRLENRNNQKPDRDGERNMEVTPGEKILRNTKEQ-RDLHNRLREIDEKLKMMKENVLEST 400
E + ++ ++ E+ ++ E+ +R +E+ + ++RE +EK++ +E + E
Sbjct: 635 WEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQE 694
Query: 401 SCLSEEQLK 409
+ ++ K
Sbjct: 695 EKMRGQEEK 703
Score = 41.6 bits (96), Expect = 0.002
Identities = 70/401 (17%), Positives = 168/401 (41%), Gaps = 62/401 (15%)
Query: 81 KLAEEGSDEDLDLVQHQIISECSDEPKLKELDSQLQDAIQKMKKLDKILAKKQRREKEIK 140
+L +E L+L ++ I +E +LK+ +++LQ+ K++ + ++ Q KE+K
Sbjct: 163 ELTKERDALSLELYRNTITNE-----ELKKKNAELQE---KLRLAESEKSEIQLNVKELK 214
Query: 141 KQGLEMRIKLWEEIKSAKYSEAWQSKEEMENTKKFLSLTAVSEETVGPSHEEEDTFSSVF 200
++ + L + + E W+ +EE+ +K + EE + E +
Sbjct: 215 RKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKI---RKQEEKMWRQEER------LR 265
Query: 201 HTQIPPEEYEMQMQKLNKDFTCDVERNESLIKSGKKPFSNTEKIELRGKHNQDFIKRNIE 260
+ E E +M++ K + E ++ +K +K+ + + Q+ ++ E
Sbjct: 266 EQEGKMREQEEKMRRQEK----RLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWE 321
Query: 261 LAKESRNPVVMVDREKKRLVELLKDLDEKDSGLSSSEGDQSGWVVPVKGYELAVTQHQQL 320
++ R + R+++RL E K + E++ + Q +++
Sbjct: 322 QEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRD--------------------QEERM 361
Query: 321 AEIDIKLQELSAASPTISSFSPRLENRNNQKPDRDGERNMEVTPGEKILRNTKEQRDLHN 380
E D +L+E + ++ ++ E+ ++ E+I K+ R+
Sbjct: 362 WEQDERLRE---------------KEERMREQEKMWEQEEKMQEEERIREREKKMREEEE 406
Query: 381 RLREIDEKLKMMKENVLESTSCLSEEQLKCLLDECILKQKSIIKLSSE--RKKEDIEDVT 438
+RE +EK++ +EN+ E ++Q E + +Q+ + + + ++E I D
Sbjct: 407 TMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQE 466
Query: 439 PVFPQLSRSIISKLLNESETKV----QKTEVEDADMLESEE 475
++ Q + + + E E ++ +K ++ M + EE
Sbjct: 467 EMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEE 507
Score = 41.6 bits (96), Expect = 0.002
Identities = 83/440 (18%), Positives = 170/440 (38%), Gaps = 53/440 (12%)
Query: 63 ENRRTSNDDKQESCSEKIKLAEEGSDEDLDLVQHQIISECSDEPKLKELDSQLQD---AI 119
E + K EK+ EE E ++ Q E +L+E + +L++ +
Sbjct: 240 EEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKEL 299
Query: 120 QKMKKLDKILAKKQRREKEIKKQGLEMR----------IKLWEEIKSAKYSE-------- 161
++ KKL + + Q +E+++ +Q +MR +LWE+ K + E
Sbjct: 300 REQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEE 359
Query: 162 -AWQSKEEMENTKKFLSLTAVSEETVGPSHEEEDTFSSVFHTQIPPEEYEMQMQKLNKDF 220
W+ E + ++ + E EEE + E Q +K+ K
Sbjct: 360 RMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQE 419
Query: 221 TCDVERNESLIKSGKKPFSNTEKIELRGKHNQDFIKRNIELAKESRNPVVMVDREKK--- 277
E+ E + + P + E Q+ ++ E ++ R+ M +EKK
Sbjct: 420 ENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQE--EKIWEQEEKIRDQEEMWGQEKKMWR 477
Query: 278 --RLVELLKDLDEKDSGLSSSEGDQSGWVVPVKGYELAVTQHQQLAEIDIKLQELSAASP 335
++ E + E++ + E Q W Q +++ E D +L+E
Sbjct: 478 QEKMREQEDQMWEQEEKMRDQE--QKMW-----------DQEERMWEQDERLREKEERMR 524
Query: 336 TISSFSPRLENRNNQKPDRDGERNMEVTPGEKILRNTKEQRDLHNRLREIDEKLKMMKEN 395
+ E +K ++ E+ + E+ +R + R+ ++RE +E ++ +E
Sbjct: 525 EQKKMWQQEEKMREEKKTQEQEK--KTWDQEEKMREEERMREREKKMREEEEMMREQEEK 582
Query: 396 VLESTSCLSEEQLKCLLDECILKQKSIIKLSSERKKEDIEDVTPVFPQLSRSIISKLLNE 455
+ E + E++ K E ++++ E K + E+ + Q +++ E
Sbjct: 583 MQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQ------EEMMWE 636
Query: 456 SETKVQKTEVEDADMLESEE 475
E K+Q+ E + M E EE
Sbjct: 637 QEEKMQEQEEK---MWEQEE 653
Score = 40.0 bits (92), Expect = 0.006
Identities = 81/403 (20%), Positives = 172/403 (42%), Gaps = 60/403 (14%)
Query: 78 EKIKLAEEGSDEDLDLVQHQIISECSDEPKLKELDSQLQDAIQKMKKLDKILAKKQRREK 137
E++ EE E ++ Q E +L+E + ++++ +KM++ +K L + +EK
Sbjct: 234 EEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRL---REQEK 290
Query: 138 EIKKQGLEMRIKLWEEIKSAKYSEAWQSKEEMENTKKFLSLTAVSEETVGPSHEEEDTFS 197
E+++Q E+R E+ K + E Q +EE K + + E+ +EE +
Sbjct: 291 ELREQEKELR----EQKKLREQEEQMQEQEE----KMWEQEEKMREQEEKMWRQEERLW- 341
Query: 198 SVFHTQIPPEEYEMQMQKLNKDFTCDVERNESLIKSGKKPFSNTEKI---ELRGKHNQDF 254
E E QM+ E+ + + ++ + E++ E R + +
Sbjct: 342 ----------EQEKQMR----------EQEQKMRDQEERMWEQDERLREKEERMREQEKM 381
Query: 255 IKRNIELAKESRNPVVMVDREKK--RLVELLKDLDEKDSGLSSSEGDQSGWVVPVKGYEL 312
++ ++ +E R + +REKK E +++ +EK + +++ W K +
Sbjct: 382 WEQEEKMQEEER----IREREKKMREEEETMREQEEK-----MQKQEENMWEQEEKEW-- 430
Query: 313 AVTQHQQLAEIDIKLQELSAASPTISSFSPRLENRNNQKPDRDGERNMEVTPGEKILRNT 372
Q Q+L E KL E + E +Q+ E+ M EK+
Sbjct: 431 ---QQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKM--WRQEKMREQE 485
Query: 373 KEQRDLHNRLREIDEKLKMMKENVLESTSCLSEEQLKCLLDECILKQKSIIKLSSERKKE 432
+ + ++R+ ++K+ +E + E L E++ + + + +Q+ K+ E+K +
Sbjct: 486 DQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEE--KMREEKKTQ 543
Query: 433 DIEDVTPVFPQLSRSIISKLLNESETKVQKTEVEDADMLESEE 475
+ E T + Q + + + E E K+++ E+ M E EE
Sbjct: 544 EQEKKT--WDQEEKMREEERMREREKKMRE---EEEMMREQEE 581
Score = 38.1 bits (87), Expect = 0.022
Identities = 29/125 (23%), Positives = 59/125 (47%), Gaps = 3/125 (2%)
Query: 70 DDKQESCSEKIKLAEEGSDEDLDLVQHQIISECSDEPKLKELDSQLQDAIQKMKKLDKIL 129
+DK + E + EE E + + Q E K++E + ++Q +KM++ ++ +
Sbjct: 624 EDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKM 683
Query: 130 --AKKQRREKEIKKQGLEMRIKLWEEIKSAKYSEAWQSKEEMENTKKFLSLTAVSEETVG 187
+++ RE+E K +G E ++ EE + + W +E E ++ +E +
Sbjct: 684 QGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERL- 742
Query: 188 PSHEE 192
P HEE
Sbjct: 743 PEHEE 747
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 55.5 bits (132), Expect = 1e-07
Identities = 93/461 (20%), Positives = 195/461 (42%), Gaps = 78/461 (16%)
Query: 79 KIKLAEEGSDEDLDLVQHQIISECSDE----PKLKELDSQLQDAIQKMKKLDKILAKKQR 134
K++LA++ +E+L ++ E + + K++EL+SQ+ + + ++ K ++
Sbjct: 1075 KMQLAKK--EEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEK 1132
Query: 135 REKEIKKQGLEMRIKLWEEIKSAKYSEAWQSKEEMENTKKFLSLTAVSEETVGPSHEEED 194
+++++ ++ ++ +L + + S + +SK E E +++ + E +HE +
Sbjct: 1133 QKRDLGEELEALKTELEDTLDSTAAQQELRSKREQE-----VNILKKTLEEEAKTHEAQI 1187
Query: 195 TFSSVFHTQIPPEEYEMQMQKLNKDFTCDVERNESLIKSGKKPFSNTEKIELRGKHNQDF 254
H+Q E E Q K ++E+ + +++ + +N K+ L+GK + +
Sbjct: 1188 QEMRQKHSQAVEELAEQLEQ--TKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEH 1245
Query: 255 IKRNIE---------------LAKESRNPVVMVDREKKRLVELLKDLDEKDSGLSSSEGD 299
++ +E + E + V + E + LL D K S L+
Sbjct: 1246 KRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSA 1305
Query: 300 QSGWVVPVKGYELAVTQHQQLAEIDIKLQELSAASPTISSFSPRLENRNNQKPD------ 353
+ + EL +++Q + KL+++ +SF +LE K +
Sbjct: 1306 LESQLQDTQ--ELLQEENRQKLSLSTKLKQVEDEK---NSFREQLEEEEEAKHNLEKQIA 1360
Query: 354 ------RDGERNMEVTPG-----EKILRNTKEQRDLHNRLREIDEKLKMMKENVLESTSC 402
D ++ ME + G E++ R K Q+DL + +EK+ + LE T
Sbjct: 1361 TLHAQVADMKKKMEDSVGCLETAEEVKR--KLQKDLEGLSQRHEEKVAAYDK--LEKTKT 1416
Query: 403 LSEEQLKCLLDECILKQKSIIKLSSERKKEDIEDVTPVFPQLSRSIISKLLNESETKVQK 462
+++L LL + +++S L ++KK D +LL E +T +
Sbjct: 1417 RLQQELDDLLVDLDHQRQSACNLEKKQKKFD-----------------QLLAEEKT-ISA 1458
Query: 463 TEVEDADMLESEECEASKGYYLTKALT-GHNMSEALVTEAE 502
E+ D E+E E TKAL+ + EA+ +AE
Sbjct: 1459 KYAEERDRAEAEAREKE-----TKALSLARALEEAMEQKAE 1494
Score = 40.0 bits (92), Expect = 0.006
Identities = 91/466 (19%), Positives = 184/466 (39%), Gaps = 88/466 (18%)
Query: 58 ESSNTENRRTSNDDKQESCSEKIKLAEEGSDEDLDLVQHQIISECSDEPKLKELD----- 112
E N + +D K ++ E + +L+Q + + S KLK+++
Sbjct: 1281 ELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNS 1340
Query: 113 --SQLQDAIQKMKKLDKILAKKQRREKEIKKQ----------GLEMRIKLWEEIK--SAK 158
QL++ + L+K +A + ++KK+ E++ KL ++++ S +
Sbjct: 1341 FREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQR 1400
Query: 159 YSEAWQSKEEMENTKKFLSLTAVSEETVGPSHEEEDTFSSVFHTQIPPEEYEMQMQKLNK 218
+ E + +++E TK L E +D + H + + ++K K
Sbjct: 1401 HEEKVAAYDKLEKTKTRL------------QQELDDLLVDLDHQR----QSACNLEKKQK 1444
Query: 219 DFTCDVERNESLIKSGKKPFSNTEKIELRGKHNQDF-IKRNIELAKESRNPVVMVDREKK 277
F + E I + + + E R K + + R +E A E +K
Sbjct: 1445 KFD-QLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAME----------QKA 1493
Query: 278 RLVELLKDLDEKDSGLSSSEGDQSGWVVPVKGYELAVTQHQQLAEIDIKLQELSAASPTI 337
L L K + L SS+ D V ++ + A+ QQ+ E+ +L+EL
Sbjct: 1494 ELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRAL--EQQVEEMKTQLEEL------- 1544
Query: 338 SSFSPRLENRNNQKPDRDGERNMEVTPGEKILRNTKEQ--RDLHNRLREIDEKLKMMKEN 395
+ + D + +EV L+ K Q RDL R + +EK K +
Sbjct: 1545 ---------EDELQATEDAKLRLEVN-----LQAMKAQFERDLQGRDEQSEEKKKQLVRQ 1590
Query: 396 VLESTSCLSEEQLKCLLDECILKQKSIIKLSSERKKEDIEDVTPVFPQLSRSIISKLLNE 455
V E + L +E+ KQ+S+ + ++ + D++D+ + +K +E
Sbjct: 1591 VREMEAELEDER----------KQRSMAVAARKKLEMDLKDL-----EAHIDSANKNRDE 1635
Query: 456 SETKVQKTEVEDAD-MLESEECEASKGYYLTKALTGHNMSEALVTE 500
+ +++K + + D M E ++ AS+ L +A +++ E
Sbjct: 1636 AIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAE 1681
Score = 38.5 bits (88), Expect = 0.017
Identities = 99/476 (20%), Positives = 199/476 (41%), Gaps = 69/476 (14%)
Query: 31 LEVLSTEPGSFKVDTASNLNSGKEDHSESSNTENRRTSNDDKQESCSEKIKLAEEGSDED 90
+E L ++ + K+ L + E +E+ R T+ + E ++ E E+
Sbjct: 871 METLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVE---EE 927
Query: 91 LDLVQHQIISECSDEPKLKELDSQLQD--------------AIQKMKKL--DKILAKKQR 134
+ QH + + ++EL+ QL++ K+KKL ++I+ + Q
Sbjct: 928 EERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQN 987
Query: 135 REKEIKKQGLEMRI-----KLWEEIKSAKYSEAWQSKEEMENT----------KKFLSLT 179
+ +K+ LE RI L EE + +K ++K E T K+ L
Sbjct: 988 CKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELE 1047
Query: 180 AVSEETVGPSHEEEDTFSSVFHTQIPPEEYEMQMQKLNKDFTCDVERNESLIKSGKKPFS 239
+ G S + D + + Q E +MQ+ K ++ + R E ++ +K +
Sbjct: 1048 KTRRKLEGDSTDLSDQIAEL---QAQIAELKMQLAKKEEELQAALARVEE--EAAQKNMA 1102
Query: 240 NTEKIELRGKHNQDFIKRNIELAKESRNPVVMVDREKKRLVELLKDLDEKDSGLSSSEGD 299
+ EL + ++ ++ ++E + SRN R+ +E LK E + L S+
Sbjct: 1103 LKKIRELESQISE--LQEDLESERASRNKAEKQKRDLGEELEALK--TELEDTLDSTAAQ 1158
Query: 300 QSGWVVPVKGYELAVTQHQQLAEIDIKLQELSAASPTISSFSPRLENRNNQKPDRDGERN 359
Q EL + Q E++I + L + T + + +++Q + E+
Sbjct: 1159 Q----------ELRSKREQ---EVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQ- 1204
Query: 360 MEVTPGEKILRNTKEQRDLHNRLREIDEKLKMMKENVLESTSCLSEEQLKCLLDECILKQ 419
+E T K K ++ L N E+ ++K++ + + SE + K + E L++
Sbjct: 1205 LEQTKRVK-ANLEKAKQTLENERGELANEVKVLLQGKGD-----SEHKRKKV--EAQLQE 1256
Query: 420 KSIIKLSSERKKEDIED-VTPVFPQLSRSIISKLLNESETKVQKTEVEDADMLESE 474
+ ER + ++ D VT + Q+ ++ LL++S++K K +D LES+
Sbjct: 1257 LQVKFNEGERVRTELADKVTKL--QVELDNVTGLLSQSDSKSSKL-TKDFSALESQ 1309
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 55.1 bits (131), Expect = 2e-07
Identities = 98/494 (19%), Positives = 202/494 (40%), Gaps = 85/494 (17%)
Query: 26 SSNASLEVLSTEPGSFKVDTASNLNSGKEDHSESSNTENRRTSNDDKQ--ESCSEKIKLA 83
S LE+ S + + N +E + + E +++S K+ E+ ++K+A
Sbjct: 926 SHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQGELKIA 985
Query: 84 EEGSDEDLDLVQHQIISECSDEPKLKELDSQLQDAIQKMKKLDK------------ILAK 131
E + +Q Q+ + KE S LQ+ +K ++ K +LA
Sbjct: 986 VLQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQSDFYGRESELLAT 1045
Query: 132 KQRREKEIKKQGLEM------------RIKLWEEIKSAKYS-EAWQSKEEMENTKKFLSL 178
+Q + +K L + KL +E+K+AK + E +K+E + ++ +L
Sbjct: 1046 RQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQERCKAL 1105
Query: 179 TAVSEETVGPSHEEEDTFSSVFHTQIPPEEYEMQMQKLNKDFTCDVERNESLIKSGK--K 236
+ +E E + S + + E ++ KLN++ + I + K K
Sbjct: 1106 QDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLESIKEITNLKDAK 1165
Query: 237 PFSNTEKIELRGKHNQDFIKRNIELAKESRNPVVMVDREKKRLVELLKDLDEKDSGLSSS 296
+K+EL+GK D +K +E +E RN ++ D+ KK EL K+ EK++ L S
Sbjct: 1166 QLLIQQKLELQGK--ADSLKAAVE--QEKRNQQILKDQVKKEEEELKKEFIEKEAKLHSE 1221
Query: 297 EGDQSGWVVPVKGYELAVTQHQQLAEIDIKLQELSAASPTISSFSPRLENRNNQKPDRDG 356
+K E+ + +H++ +
Sbjct: 1222 ----------IKEKEVGMKKHEE----------------------------------NEA 1237
Query: 357 ERNMEVTP-GEKILRNTKEQRDLHNRLREIDEKLKMMKEN--VLESTSCLSEEQLKCLLD 413
+ M++T E + KE + R+ E++++ ++ VLE+T ++++ + LL+
Sbjct: 1238 KLTMQITALNENLGTVKKEWQSSQRRVSELEKQTDDLRGEIAVLEATVQNNQDERRALLE 1297
Query: 414 ECILKQKSIIKLSSE--RKKEDIEDVTPVFPQLSRSIISKLLNESETKVQKTEVEDADML 471
C+ + I KL ++ + +++ T +L R S + ++ + + ED ++
Sbjct: 1298 RCLKGEGEIEKLQTKVLELQRKLDNTTAAVQELGRENQSLQIKHTQA-LNRKWAEDNEVQ 1356
Query: 472 ESEECEASKGYYLT 485
C KG+ +T
Sbjct: 1357 NCMAC--GKGFSVT 1368
Score = 50.4 bits (119), Expect = 4e-06
Identities = 96/500 (19%), Positives = 207/500 (41%), Gaps = 70/500 (14%)
Query: 25 RSSNASLEVLSTEPGSFKVDTASNLNSGKEDHSESSNTENRRTSNDDKQESCSEKIKLAE 84
+ S ++ +L E + D + + +G+ + + + + + + ++ +EK+K
Sbjct: 533 QKSKENISLLEKE----REDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQS 588
Query: 85 EGSDEDLDLVQHQIISE-----------CSDEPKLKELDSQLQDAIQKMKKLDKILAKKQ 133
E + + + Q+ + S E + EL+SQL ++ +K+ +LD + K
Sbjct: 589 ESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQIKAKT 648
Query: 134 RREKEIKKQGLEMRIKLWEEIKSAKYSEAWQSKEEMENTKKFLSLTAVSEETVGPSHEEE 193
+ R L + +A+ + + +E + T + +TA ++ + E
Sbjct: 649 ELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLE 708
Query: 194 DTF----SSVFHTQIPPEEYEMQMQKLNKDFTCDVERNESLIKSGKKPFSNTEKIELRGK 249
+ EE E Q++KL D E ++ ++ +ELR
Sbjct: 709 SHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRAT 768
Query: 250 HNQDFIKRNIELAKESRNPVVMVDREKKRLVELLKD---LDEKDSGLSSSEGDQSGWVVP 306
+ + +E+ KE + + ++K +E +K E++ + + +
Sbjct: 769 E----LSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETK 824
Query: 307 VKGYEL------AVTQHQQL-AEIDIKLQELSAASPTISSFSPRLENRNNQKPDRDGERN 359
++ EL VT+ Q++ E + + ELS +S S L+N ++ + +
Sbjct: 825 IQHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGK 884
Query: 360 MEVTPGEKI-----------LRNT-KEQRDLHNRL---REIDEKLKM----MKENVLEST 400
+ EK + NT KEQ++L L +E +LK+ M+E ++++
Sbjct: 885 AAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQ 944
Query: 401 SCL-----SEEQLKCLLDECILKQKSIIKLSSERKKEDIEDVTPVFPQLSRSIISKLLNE 455
+ L E+QL+ ++E +K SSE+KK+ IE + +L +++ K E
Sbjct: 945 NTLKQNEKEEQQLQGNINE--------LKQSSEQKKKQIEALQ---GELKIAVLQK--TE 991
Query: 456 SETKVQKTEVEDADMLESEE 475
E K+Q+ + A L +E+
Sbjct: 992 LENKLQQQLTQAAQELAAEK 1011
Score = 46.6 bits (109), Expect = 6e-05
Identities = 92/444 (20%), Positives = 176/444 (39%), Gaps = 82/444 (18%)
Query: 69 NDDKQESCSEKIKLAEEGSDEDLDLVQHQIISECSDEPKLKELDSQLQDAIQKMKKLDKI 128
+D + S SE K ++G LDL E KEL QLQ ++ K K
Sbjct: 866 SDSLKNSKSEFEKENQKGKAAILDL-----------EKTCKELKHQLQVQMENTLKEQKE 914
Query: 129 LAKKQRREKEIKKQGLEMRIKLWEEIKSAKYSEAWQSKEEMENTKKFLSLTAVSEETVGP 188
L K +EKE Q L++ + +E + Q++ ++ +K
Sbjct: 915 LKKSLEKEKEASHQ-LKLELNSMQE-------QLIQAQNTLKQNEK-------------- 952
Query: 189 SHEEEDTFSSVFHTQIPPEEYEMQMQKLNKDFTCDVERNESLIKSGKKPFSNTEKIELRG 248
EE+ ++ + E+ + Q++ L G+ + +K EL
Sbjct: 953 --EEQQLQGNINELKQSSEQKKKQIEAL----------------QGELKIAVLQKTELEN 994
Query: 249 KHNQDFIKRNIELAKESRNPVVM---VDREKKRLVELLKDLDEKDSGLSSSEGDQSGWVV 305
K Q + ELA E V+ ++ ++ +L D ++S L ++ D
Sbjct: 995 KLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQSDFYGRESELLATRQDLKSVEE 1054
Query: 306 PVK-GYELAVTQHQQLAEIDIKLQELSAASPTISSFSPRLENRNNQKPDRDGERNMEVTP 364
+ E ++ Q+ + +QEL A T+ S + E + ++ + E +
Sbjct: 1055 KLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSL 1114
Query: 365 GEKILRNTK----EQRDLHNR----LREIDEKLKMMK-ENVLESTSCLSEEQLKCLLDEC 415
EK L N K E ++ R + +++E+LK K E++ E T+ +QL
Sbjct: 1115 KEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQL------- 1167
Query: 416 ILKQKSIIKLSSERKKEDIEDVTPVFPQLSRSIISKLLNESETKVQKTEVEDADMLESEE 475
+++QK ++ ++ K +E + ++ I+ + + E +++K +E L SE
Sbjct: 1168 LIQQKLELQGKADSLKAAVEQ-----EKRNQQILKDQVKKEEEELKKEFIEKEAKLHSEI 1222
Query: 476 CEASKGYYLTKALTGHNMSEALVT 499
E G + H +EA +T
Sbjct: 1223 KEKEVG------MKKHEENEAKLT 1240
Score = 43.9 bits (102), Expect = 4e-04
Identities = 77/437 (17%), Positives = 178/437 (40%), Gaps = 58/437 (13%)
Query: 107 KLKELDSQLQDAIQKMKKLDKILAKKQRREKEIKKQGLEMRIKLWEEIKSAKYSEAWQSK 166
KL E + QL +A ++K+ + L+ ++ +KE + L++++ EE K + + + +
Sbjct: 422 KLLETERQLGEAHGRLKE-QRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQ 480
Query: 167 EEMENTKK-FLSLTAVSEETVGPSHEEEDTFSSVFHTQIPPEEYEMQMQKLNKDFTCDVE 225
+++ TK+ A+ + T E ++ V QI ++ ++Q
Sbjct: 481 HQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLR-QIGDKDQKIQ------------- 526
Query: 226 RNESLIKSGKKPFSNTEKIELRGKHNQDFIKRNIELAKESRNPVVMVDREKKRLVELLKD 285
E+L++ K E I L K +D + I+ + + + + L E +
Sbjct: 527 NLEALLQKSK------ENISLLEKEREDLYAK-IQAGEGETAVLNQLQEKNHTLQEQVTQ 579
Query: 286 LDEKDSGLSSSEGDQSGWVVPVKGYELAVTQHQQLAEIDIKLQELSAASPTISSFSPRLE 345
L EK S S + H Q+ E L+ ++ + L
Sbjct: 580 LTEKLKNQSESHK------------QAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELN 627
Query: 346 NRNNQKPDRDGERNMEVTPGEKILRN-----TKEQRDLHNRL-------REIDEKLKMMK 393
++ N+ ++ + ++++ ++L + T ++ DL N L ++ ++L +
Sbjct: 628 SQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKIT 687
Query: 394 ENVLESTSCLSEEQLKCLLDECILKQKSIIKLSSERKKEDIE-----------DVTPVFP 442
+ + T+ L ++Q C E LK+ LS E+K E++E +V
Sbjct: 688 TQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKE 747
Query: 443 QLSRSIISKLLNESETKVQKTEVEDADMLESEECEASKGYYLTKALTGHNMSEALVTEAE 502
Q + + + ++ +++ TE+ +E E +++ K+ ++ + L + E
Sbjct: 748 QALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEE 807
Query: 503 NMKCLQFSKDVIISDTK 519
+ L+ + + +TK
Sbjct: 808 EKQILKQDFETLSQETK 824
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 53.5 bits (127), Expect = 5e-07
Identities = 71/380 (18%), Positives = 164/380 (43%), Gaps = 43/380 (11%)
Query: 70 DDKQESCSEKIKLAEEGSDEDLDLVQHQIISECSDEPKLKELDSQLQDAIQKMKKLDKIL 129
++K + EKI+ EE E + ++ Q E K++ + + + +KM++L++++
Sbjct: 313 EEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMM 372
Query: 130 AKKQRREKEIKKQGLEM-RIKLWEEIKSAKYSEAWQSKEEMENTKKFLSLTAVSEETVGP 188
+K+ + +E++++ E +I+ EE + + Q K + + K + + E+
Sbjct: 373 WEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKI 432
Query: 189 SHEEEDTF--SSVFHTQIPPEEYEMQMQKLNKDFTCDVERNESLIKSGKKPFSNTEKIEL 246
+E+ + H Q E E + ++ ++ R E I+ ++ + EK+
Sbjct: 433 REQEKKMWRQEEKIHEQEKIREEEKRQEQE------EMWRQEEKIREQEEIWRQKEKM-- 484
Query: 247 RGKHNQDFIKRNIELAKESRNPVVMVDREKK---------RLVELLKDLDEKDSGLSSSE 297
H Q+ I++ E K R M D+E+K R E +++ +EK
Sbjct: 485 ---HEQEKIRKQEE--KVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKI 539
Query: 298 GDQSGWVVPVKGYELAVTQHQQLAEIDIKLQELSAASPTISSFSPRLENRNNQKPDRDGE 357
+Q E+ Q +++ E + K+QE R E + ++ ++ E
Sbjct: 540 REQE---------EMMQEQEEKMGEQEEKMQEQEKMR--------RQEEKIREQEEKIRE 582
Query: 358 RNMEVTPGE-KILRNTKEQRDLHNRLREIDEKLKMMKENVLESTSCLSEEQLKCLLDECI 416
+ ++ E KI ++ R+ ++E +EK+ +E + E + E++ K E
Sbjct: 583 QKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK 642
Query: 417 LKQKSIIKLSSERKKEDIED 436
+ ++ + E K ++ ++
Sbjct: 643 MWEQEVRLRQQEEKMQEHQE 662
Score = 45.1 bits (105), Expect = 2e-04
Identities = 85/437 (19%), Positives = 180/437 (41%), Gaps = 93/437 (21%)
Query: 52 GKEDHSESSNTENRRTSND---DKQESCSEKIKLAEEGSDEDLDLVQHQIISECSDEPKL 108
GKE S S+ + + N+ + EK+ EE E + +Q Q E K+
Sbjct: 271 GKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQ-------EEKI 323
Query: 109 KELDSQLQDAIQKMKKLDKILAKKQ---RREKEIKKQGLEMRIKLWEEIKSAKYSEA--W 163
+E + ++++ +KM++ ++++ +K+ RR++E+ +WE+ + + E W
Sbjct: 324 REQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEM----------MWEKEEKMRRLEEMMW 373
Query: 164 QSKEEMENTKKFLSLTAVSEETVGPSHEEEDTFSSVFHTQIPPEEYEMQMQKLNKDFTCD 223
+ +E++ ++ + E EEE Q +E E +M + +
Sbjct: 374 EKEEKIRELEEKMHEQEKIREQEEKRQEEEK-----IREQEKRQEQEAKMWRQEEKIR-- 426
Query: 224 VERNESLIKSGKKPFSNTEKIELRGKHNQDFIKRNIELAKESRNPVVMVDREKKRLVELL 283
E+ E + + KK + EKI H Q+ I+ + EK++ E +
Sbjct: 427 -EQEEKIREQEKKMWRQEEKI-----HEQEKIR----------------EEEKRQEQEEM 464
Query: 284 KDLDEKDSGLSSSEGDQSGWVVPVKGYELAVTQHQQLAEID-IKLQELSAASPTISSFSP 342
+EK ++ E Q +++ E + I+ QE
Sbjct: 465 WRQEEK-----------------IREQEEIWRQKEKMHEQEKIRKQEEKVW--------- 498
Query: 343 RLENRNNQKPDRDGERNMEVTPGEKILRNTKEQRDLHNRLREIDEKLKMMKENVLESTSC 402
R E + + + ++ E+ EK+ R ++ R+ ++RE +EK++ +E + E
Sbjct: 499 RQEEKMHDQEEKIREQE------EKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEK 552
Query: 403 LSEEQLKCLLDECILKQKSIIKLSSERKKEDIEDVTPVFPQLSRSIISKLLNESETKVQK 462
+ E++ K E + +Q+ I+ E+ +E E + ++ + + E E +Q+
Sbjct: 553 MGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQ--EEKIREQEEMMQE 610
Query: 463 TE----VEDADMLESEE 475
E ++ M E EE
Sbjct: 611 QEEKMWEQEEKMCEQEE 627
Score = 42.0 bits (97), Expect = 0.002
Identities = 73/375 (19%), Positives = 152/375 (40%), Gaps = 41/375 (10%)
Query: 71 DKQESCSEKIKLAE-EGSDEDLDLVQHQIISECSDEPKLKELDSQLQ-DAIQKMKKLDKI 128
+K EK++L E E S+ L++ + + + KL QLQ +A K+L +
Sbjct: 221 EKNAKLQEKLQLVESEKSEIQLNVKE---LKRKLERAKLLLPQQQLQAEADHLGKELQSV 277
Query: 129 LAKKQRREKEIKKQGLEMRIKLWEEIKSAKYSEAWQSKEEMENTKKFLSLTAVSEETVGP 188
AK Q + +E + LW + + + W+ +E+++ ++ + EE +
Sbjct: 278 SAKLQAQVEENE---------LWNRLNQQQEEKMWRQEEKIQEWEEKIQ---EQEEKI-- 323
Query: 189 SHEEEDTFSSVFHTQIPPEEYEMQMQ-KLNKDFTCDVERNESLIKSGKKPFSNTEKI-EL 246
E+E+ EE + + K+ + E+ E + + + + EKI EL
Sbjct: 324 -REQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIREL 382
Query: 247 RGK-HNQDFIKRNIELAKESRNPVVMVDREKK-----RLVELLKDLDEKDSGLSSSEGDQ 300
K H Q+ I+ E +E R+++ R E +++ +EK E ++
Sbjct: 383 EEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEK-----IREQEK 437
Query: 301 SGWVVPVKGYELAVTQHQQLAEIDIKLQELSAASPTISSFSPRLENRNNQKPDRDGERNM 360
W K +E + ++ + ++ + E + Q+ R E
Sbjct: 438 KMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQE--- 494
Query: 361 EVTPGEKILRNTKEQRDLHNRLREIDEKLKMMKENVLESTSCLSEEQLKCLLDECILKQK 420
EK+ R ++ D ++RE +EK+ +E + E + E++ K E +++++
Sbjct: 495 -----EKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQ 549
Query: 421 SIIKLSSERKKEDIE 435
E K ++ E
Sbjct: 550 EEKMGEQEEKMQEQE 564
Score = 42.0 bits (97), Expect = 0.002
Identities = 23/116 (19%), Positives = 55/116 (47%), Gaps = 1/116 (0%)
Query: 54 EDHSESSNTENRRTSNDDKQESCSEKIKLAEEGSDEDLDLVQHQIISECSDEPKLKELDS 113
++ E + + +K EKI+ EE E + ++ Q E K++E +
Sbjct: 547 QEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEE 606
Query: 114 QLQDAIQKMKKLDKILAKKQRREKEIKKQGLEMRIKLWE-EIKSAKYSEAWQSKEE 168
+Q+ +KM + ++ + +++ + +E +++ K+WE E++ + E Q +E
Sbjct: 607 MMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 662
Score = 34.7 bits (78), Expect = 0.25
Identities = 38/229 (16%), Positives = 99/229 (43%), Gaps = 14/229 (6%)
Query: 249 KHNQDFIKRNIELAKESRNPVVMVDREKKRLVELLKDLDEKDSGLSSSEGDQSGWVVPVK 308
++ ++ K L+ E + + K++ +L + L +S S + + ++
Sbjct: 193 RYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLE 252
Query: 309 GYELAVTQHQQLAEIDIKLQELSAASPTISSFSPRLE--NRNNQKPDRDGERNMEVTPGE 366
+L + Q Q AE D +EL + S + + E NR NQ+ + E
Sbjct: 253 RAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQE------------E 300
Query: 367 KILRNTKEQRDLHNRLREIDEKLKMMKENVLESTSCLSEEQLKCLLDECILKQKSIIKLS 426
K+ R ++ ++ +++E +EK++ +E + E + ++ E ++++ +
Sbjct: 301 KMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE 360
Query: 427 SERKKEDIEDVTPVFPQLSRSIISKLLNESETKVQKTEVEDADMLESEE 475
E K +E++ + R + K+ + + + Q+ + ++ + + +E
Sbjct: 361 KEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE 409
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 53.1 bits (126), Expect = 7e-07
Identities = 110/527 (20%), Positives = 214/527 (40%), Gaps = 71/527 (13%)
Query: 44 DTASNLNSGKEDHSESSNTENRRTSNDDKQESCSEKIKLAEEGSDEDLDLVQHQIISECS 103
+ A NL K H + R ++K EK+K EG D H+ I++
Sbjct: 1020 EKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDF----HEQIADL- 1074
Query: 104 DEPKLKELDSQLQDAIQKMK----KLDKILAKKQRREKEIKKQGLEMRIK-LWEEIKSAK 158
+ ++ EL QL ++++ +LD +A+K K+I++ LE I L E++ S +
Sbjct: 1075 -QAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRE--LEGHISDLQEDLDSER 1131
Query: 159 YSEAWQSK------EEMENTKKFLSLTAVSEETVGPSHEEEDTFSSVFHTQIPPE--EYE 210
+ K EE+E K L T S T + + +V + E +E
Sbjct: 1132 AARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHE 1191
Query: 211 MQMQKLNKDFTCDVERNESLIKSGKKPFSNTEKIELRGKHNQDFIKRNIELAKESR---N 267
Q+Q++ + VE ++ K+ +N + K+ Q K N +LA E R
Sbjct: 1192 AQVQEMRQKHAQAVEELTEQLEQFKRAKANLD------KNKQTLEKENADLAGELRVLGQ 1245
Query: 268 PVVMVDREKKRLVELLKDLDEKDSG--------------LSSSEGDQSGWVVPVKGYELA 313
V+ +KK+L +++L K S L + +G + +G +
Sbjct: 1246 AKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIK 1305
Query: 314 VTQ-----HQQLAEIDIKLQELSAASPTISSFSPRLENRNNQKPDR-----DGERNME-- 361
+ + QL + LQE + +S+ +LE N D+ + ++N+E
Sbjct: 1306 LAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERH 1365
Query: 362 -VTPGEKILRNTKEQRDLHNRLREIDEKLKMMKENVLESTSCLSEEQLKCLLDECILKQK 420
T ++ + K+ +D + + ++E K ++ + T E K + + K K
Sbjct: 1366 ISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEE---KAAAYDKLEKTK 1422
Query: 421 SIIKLSSERKKEDIEDVTPVFPQLSRS--IISKLLNESETKVQKTEVEDADMLESEECEA 478
+ ++ + D+++ + L + +LL E E + ++ D E+E E
Sbjct: 1423 NRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAE-EKNISSKYADERDRAEAEAREK 1481
Query: 479 SKGYYLTKALTGHNMSEALVTEAENMKCLQFSKDVIISDTKDYFMSK 525
TKAL +++ AL E + L+ + ++ ++ +D SK
Sbjct: 1482 E-----TKAL---SLARALEEALEAKEELERTNKMLKAEMEDLVSSK 1520
Score = 35.4 bits (80), Expect = 0.15
Identities = 52/222 (23%), Positives = 93/222 (41%), Gaps = 29/222 (13%)
Query: 273 DREKKRLVELLKDLDEKDSGLSSSEGDQSGWVVPVKGYELAVTQHQQLAEIDIKLQELSA 332
+R++K EL K+L++K S L+ + E + + AE + L+A
Sbjct: 866 ERQQKAENEL-KELEQKHSQLTEEKNLLQ---------EQLQAETELYAEAEEMRVRLAA 915
Query: 333 ASPTISSFSPRLENRNNQKPDRDGERNMEVTPGEKILRNTKEQRDLHNRLREIDEKLKMM 392
+ +E R ++ DR + E + + + +EQ + R+ K+
Sbjct: 916 KKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQ-----KLQ 970
Query: 393 KENVLESTSCLSEEQLKCLLDECILKQKSIIKLSSERK--KEDIEDVTPVFPQLSRSI-- 448
E V +E ++K L DE ++ KLS ERK +E I D+T +
Sbjct: 971 LEKVT------AEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKN 1024
Query: 449 ISKLLNESETKVQKTEVEDADMLESEECEASKGYYLTKALTG 490
++KL N+ E+ + + EV L+ EE + L + L G
Sbjct: 1025 LTKLKNKHESMISELEVR----LKKEEKSRQELEKLKRKLEG 1062
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 53.1 bits (126), Expect = 7e-07
Identities = 110/527 (20%), Positives = 214/527 (40%), Gaps = 71/527 (13%)
Query: 44 DTASNLNSGKEDHSESSNTENRRTSNDDKQESCSEKIKLAEEGSDEDLDLVQHQIISECS 103
+ A NL K H + R ++K EK+K EG D H+ I++
Sbjct: 1027 EKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDF----HEQIADL- 1081
Query: 104 DEPKLKELDSQLQDAIQKMK----KLDKILAKKQRREKEIKKQGLEMRIK-LWEEIKSAK 158
+ ++ EL QL ++++ +LD +A+K K+I++ LE I L E++ S +
Sbjct: 1082 -QAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRE--LEGHISDLQEDLDSER 1138
Query: 159 YSEAWQSK------EEMENTKKFLSLTAVSEETVGPSHEEEDTFSSVFHTQIPPE--EYE 210
+ K EE+E K L T S T + + +V + E +E
Sbjct: 1139 AARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHE 1198
Query: 211 MQMQKLNKDFTCDVERNESLIKSGKKPFSNTEKIELRGKHNQDFIKRNIELAKESR---N 267
Q+Q++ + VE ++ K+ +N + K+ Q K N +LA E R
Sbjct: 1199 AQVQEMRQKHAQAVEELTEQLEQFKRAKANLD------KNKQTLEKENADLAGELRVLGQ 1252
Query: 268 PVVMVDREKKRLVELLKDLDEKDSG--------------LSSSEGDQSGWVVPVKGYELA 313
V+ +KK+L +++L K S L + +G + +G +
Sbjct: 1253 AKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIK 1312
Query: 314 VTQ-----HQQLAEIDIKLQELSAASPTISSFSPRLENRNNQKPDR-----DGERNME-- 361
+ + QL + LQE + +S+ +LE N D+ + ++N+E
Sbjct: 1313 LAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERH 1372
Query: 362 -VTPGEKILRNTKEQRDLHNRLREIDEKLKMMKENVLESTSCLSEEQLKCLLDECILKQK 420
T ++ + K+ +D + + ++E K ++ + T E K + + K K
Sbjct: 1373 ISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEE---KAAAYDKLEKTK 1429
Query: 421 SIIKLSSERKKEDIEDVTPVFPQLSRS--IISKLLNESETKVQKTEVEDADMLESEECEA 478
+ ++ + D+++ + L + +LL E E + ++ D E+E E
Sbjct: 1430 NRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAE-EKNISSKYADERDRAEAEAREK 1488
Query: 479 SKGYYLTKALTGHNMSEALVTEAENMKCLQFSKDVIISDTKDYFMSK 525
TKAL +++ AL E + L+ + ++ ++ +D SK
Sbjct: 1489 E-----TKAL---SLARALEEALEAKEELERTNKMLKAEMEDLVSSK 1527
Score = 35.4 bits (80), Expect = 0.15
Identities = 52/222 (23%), Positives = 93/222 (41%), Gaps = 29/222 (13%)
Query: 273 DREKKRLVELLKDLDEKDSGLSSSEGDQSGWVVPVKGYELAVTQHQQLAEIDIKLQELSA 332
+R++K EL K+L++K S L+ + E + + AE + L+A
Sbjct: 873 ERQQKAENEL-KELEQKHSQLTEEKNLLQ---------EQLQAETELYAEAEEMRVRLAA 922
Query: 333 ASPTISSFSPRLENRNNQKPDRDGERNMEVTPGEKILRNTKEQRDLHNRLREIDEKLKMM 392
+ +E R ++ DR + E + + + +EQ + R+ K+
Sbjct: 923 KKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQ-----KLQ 977
Query: 393 KENVLESTSCLSEEQLKCLLDECILKQKSIIKLSSERK--KEDIEDVTPVFPQLSRSI-- 448
E V +E ++K L DE ++ KLS ERK +E I D+T +
Sbjct: 978 LEKVT------AEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKN 1031
Query: 449 ISKLLNESETKVQKTEVEDADMLESEECEASKGYYLTKALTG 490
++KL N+ E+ + + EV L+ EE + L + L G
Sbjct: 1032 LTKLKNKHESMISELEVR----LKKEEKSRQELEKLKRKLEG 1069
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 53.1 bits (126), Expect = 7e-07
Identities = 110/527 (20%), Positives = 214/527 (40%), Gaps = 71/527 (13%)
Query: 44 DTASNLNSGKEDHSESSNTENRRTSNDDKQESCSEKIKLAEEGSDEDLDLVQHQIISECS 103
+ A NL K H + R ++K EK+K EG D H+ I++
Sbjct: 1027 EKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDF----HEQIADL- 1081
Query: 104 DEPKLKELDSQLQDAIQKMK----KLDKILAKKQRREKEIKKQGLEMRIK-LWEEIKSAK 158
+ ++ EL QL ++++ +LD +A+K K+I++ LE I L E++ S +
Sbjct: 1082 -QAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRE--LEGHISDLQEDLDSER 1138
Query: 159 YSEAWQSK------EEMENTKKFLSLTAVSEETVGPSHEEEDTFSSVFHTQIPPE--EYE 210
+ K EE+E K L T S T + + +V + E +E
Sbjct: 1139 AARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHE 1198
Query: 211 MQMQKLNKDFTCDVERNESLIKSGKKPFSNTEKIELRGKHNQDFIKRNIELAKESR---N 267
Q+Q++ + VE ++ K+ +N + K+ Q K N +LA E R
Sbjct: 1199 AQVQEMRQKHAQAVEELTEQLEQFKRAKANLD------KNKQTLEKENADLAGELRVLGQ 1252
Query: 268 PVVMVDREKKRLVELLKDLDEKDSG--------------LSSSEGDQSGWVVPVKGYELA 313
V+ +KK+L +++L K S L + +G + +G +
Sbjct: 1253 AKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIK 1312
Query: 314 VTQ-----HQQLAEIDIKLQELSAASPTISSFSPRLENRNNQKPDR-----DGERNME-- 361
+ + QL + LQE + +S+ +LE N D+ + ++N+E
Sbjct: 1313 LAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERH 1372
Query: 362 -VTPGEKILRNTKEQRDLHNRLREIDEKLKMMKENVLESTSCLSEEQLKCLLDECILKQK 420
T ++ + K+ +D + + ++E K ++ + T E K + + K K
Sbjct: 1373 ISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEE---KAAAYDKLEKTK 1429
Query: 421 SIIKLSSERKKEDIEDVTPVFPQLSRS--IISKLLNESETKVQKTEVEDADMLESEECEA 478
+ ++ + D+++ + L + +LL E E + ++ D E+E E
Sbjct: 1430 NRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAE-EKNISSKYADERDRAEAEAREK 1488
Query: 479 SKGYYLTKALTGHNMSEALVTEAENMKCLQFSKDVIISDTKDYFMSK 525
TKAL +++ AL E + L+ + ++ ++ +D SK
Sbjct: 1489 E-----TKAL---SLARALEEALEAKEELERTNKMLKAEMEDLVSSK 1527
Score = 35.4 bits (80), Expect = 0.15
Identities = 52/222 (23%), Positives = 93/222 (41%), Gaps = 29/222 (13%)
Query: 273 DREKKRLVELLKDLDEKDSGLSSSEGDQSGWVVPVKGYELAVTQHQQLAEIDIKLQELSA 332
+R++K EL K+L++K S L+ + E + + AE + L+A
Sbjct: 873 ERQQKAENEL-KELEQKHSQLTEEKNLLQ---------EQLQAETELYAEAEEMRVRLAA 922
Query: 333 ASPTISSFSPRLENRNNQKPDRDGERNMEVTPGEKILRNTKEQRDLHNRLREIDEKLKMM 392
+ +E R ++ DR + E + + + +EQ + R+ K+
Sbjct: 923 KKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQ-----KLQ 977
Query: 393 KENVLESTSCLSEEQLKCLLDECILKQKSIIKLSSERK--KEDIEDVTPVFPQLSRSI-- 448
E V +E ++K L DE ++ KLS ERK +E I D+T +
Sbjct: 978 LEKVT------AEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKN 1031
Query: 449 ISKLLNESETKVQKTEVEDADMLESEECEASKGYYLTKALTG 490
++KL N+ E+ + + EV L+ EE + L + L G
Sbjct: 1032 LTKLKNKHESMISELEVR----LKKEEKSRQELEKLKRKLEG 1069
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 53.1 bits (126), Expect = 7e-07
Identities = 110/527 (20%), Positives = 214/527 (40%), Gaps = 71/527 (13%)
Query: 44 DTASNLNSGKEDHSESSNTENRRTSNDDKQESCSEKIKLAEEGSDEDLDLVQHQIISECS 103
+ A NL K H + R ++K EK+K EG D H+ I++
Sbjct: 1020 EKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDF----HEQIADL- 1074
Query: 104 DEPKLKELDSQLQDAIQKMK----KLDKILAKKQRREKEIKKQGLEMRIK-LWEEIKSAK 158
+ ++ EL QL ++++ +LD +A+K K+I++ LE I L E++ S +
Sbjct: 1075 -QAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRE--LEGHISDLQEDLDSER 1131
Query: 159 YSEAWQSK------EEMENTKKFLSLTAVSEETVGPSHEEEDTFSSVFHTQIPPE--EYE 210
+ K EE+E K L T S T + + +V + E +E
Sbjct: 1132 AARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHE 1191
Query: 211 MQMQKLNKDFTCDVERNESLIKSGKKPFSNTEKIELRGKHNQDFIKRNIELAKESR---N 267
Q+Q++ + VE ++ K+ +N + K+ Q K N +LA E R
Sbjct: 1192 AQVQEMRQKHAQAVEELTEQLEQFKRAKANLD------KNKQTLEKENADLAGELRVLGQ 1245
Query: 268 PVVMVDREKKRLVELLKDLDEKDSG--------------LSSSEGDQSGWVVPVKGYELA 313
V+ +KK+L +++L K S L + +G + +G +
Sbjct: 1246 AKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIK 1305
Query: 314 VTQ-----HQQLAEIDIKLQELSAASPTISSFSPRLENRNNQKPDR-----DGERNME-- 361
+ + QL + LQE + +S+ +LE N D+ + ++N+E
Sbjct: 1306 LAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERH 1365
Query: 362 -VTPGEKILRNTKEQRDLHNRLREIDEKLKMMKENVLESTSCLSEEQLKCLLDECILKQK 420
T ++ + K+ +D + + ++E K ++ + T E K + + K K
Sbjct: 1366 ISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEE---KAAAYDKLEKTK 1422
Query: 421 SIIKLSSERKKEDIEDVTPVFPQLSRS--IISKLLNESETKVQKTEVEDADMLESEECEA 478
+ ++ + D+++ + L + +LL E E + ++ D E+E E
Sbjct: 1423 NRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAE-EKNISSKYADERDRAEAEAREK 1481
Query: 479 SKGYYLTKALTGHNMSEALVTEAENMKCLQFSKDVIISDTKDYFMSK 525
TKAL +++ AL E + L+ + ++ ++ +D SK
Sbjct: 1482 E-----TKAL---SLARALEEALEAKEELERTNKMLKAEMEDLVSSK 1520
Score = 35.4 bits (80), Expect = 0.15
Identities = 52/222 (23%), Positives = 93/222 (41%), Gaps = 29/222 (13%)
Query: 273 DREKKRLVELLKDLDEKDSGLSSSEGDQSGWVVPVKGYELAVTQHQQLAEIDIKLQELSA 332
+R++K EL K+L++K S L+ + E + + AE + L+A
Sbjct: 866 ERQQKAENEL-KELEQKHSQLTEEKNLLQ---------EQLQAETELYAEAEEMRVRLAA 915
Query: 333 ASPTISSFSPRLENRNNQKPDRDGERNMEVTPGEKILRNTKEQRDLHNRLREIDEKLKMM 392
+ +E R ++ DR + E + + + +EQ + R+ K+
Sbjct: 916 KKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQ-----KLQ 970
Query: 393 KENVLESTSCLSEEQLKCLLDECILKQKSIIKLSSERK--KEDIEDVTPVFPQLSRSI-- 448
E V +E ++K L DE ++ KLS ERK +E I D+T +
Sbjct: 971 LEKVT------AEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKN 1024
Query: 449 ISKLLNESETKVQKTEVEDADMLESEECEASKGYYLTKALTG 490
++KL N+ E+ + + EV L+ EE + L + L G
Sbjct: 1025 LTKLKNKHESMISELEVR----LKKEEKSRQELEKLKRKLEG 1062
>gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]
Length = 1780
Score = 53.1 bits (126), Expect = 7e-07
Identities = 89/434 (20%), Positives = 179/434 (41%), Gaps = 59/434 (13%)
Query: 77 SEKIKLAEEGSDEDLDLVQHQIISECSDEPKLKELDSQLQDAIQKMKKLDKILAKKQRRE 136
++K++ + E L + II + E LKE LQD+++ K L+ K+ + +
Sbjct: 1132 TQKVECSHSAKLEQDILEKESIILKL--ERNLKEFQEHLQDSVKNTKDLN---VKELKLK 1186
Query: 137 KEIKKQGLEMRIKLWEEIKSAKYSEAWQSKEEMENTKKFLSLTAVSEETVGPS-HEEEDT 195
+EI + L ++ + + K E +++E E K+ LS ++ + + +E+
Sbjct: 1187 EEITQ--LTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEED 1244
Query: 196 FSSVFHTQIPPEEYEMQMQKLNKDFTCDVERNESLIKSGKKPFSNTEKIELRGKHNQDFI 255
++ + ++ Q+QK V R+E + K + EK + + D
Sbjct: 1245 YADLKEKLTDAKKQIKQVQK-----EVSVMRDEDKLLRIK--INELEKKKNQCSQELDMK 1297
Query: 256 KRNIELAKESRNPVVMVDREKKRLVELLKDLDEKDSGLSSSEGDQSGWVVPVKGYELAVT 315
+R I+ KE N V+ ++ KDL+ K+ + E T
Sbjct: 1298 QRTIQQLKEQLNNQ-KVEEAIQQYERACKDLNVKEKIIEDMRMTLE---------EQEQT 1347
Query: 316 QHQQLAEIDIKLQELSAASPTISSFSPR---LENRNNQKPDRDGERNMEVTPGEKILRNT 372
Q +Q ++ KL+E+ + + + + LE +NNQ+ +++ E N +V
Sbjct: 1348 QVEQDQVLEAKLEEVERLATELEKWKEKCNDLETKNNQRSNKEHENNTDV---------L 1398
Query: 373 KEQRDLHNRLREIDEKLKMMKENVLESTSCLSEEQLKCLLDECILKQKSIIKLSSERKKE 432
+ +L + L+E ++K ++ LE L I + K + ++ K+
Sbjct: 1399 GKLTNLQDELQESEQKYNADRKKWLEEKMML------------ITQAKEAENIRNKEMKK 1446
Query: 433 DIEDVTPVFPQLSR-SIISKLLNESETKVQKTEVEDADMLESEECEASKGYYLTKALTGH 491
ED F Q + I++ L E ++ +QK E ++ + E + KAL
Sbjct: 1447 YAEDRERFFKQQNEMEILTAQLTEKDSDLQKWREERDQLVAALEIQ-------LKALISS 1499
Query: 492 NMSEALVTEAENMK 505
N+ + E E +K
Sbjct: 1500 NVQKD--NEIEQLK 1511
Score = 40.0 bits (92), Expect = 0.006
Identities = 102/464 (21%), Positives = 199/464 (42%), Gaps = 65/464 (14%)
Query: 53 KEDHSESSNTENR-RTSNDDKQESCSEKIKLAEEGS------DEDLDLVQHQIISECSDE 105
KE + N EN +S + E C E +K + + S ++ ++ +Q ++ +
Sbjct: 1000 KEYRIQEPNRENSFHSSIEAIWEECKEIVKASSKKSHQIEELEQQIEKLQAEVKGYKDEN 1059
Query: 106 PKLKELDSQLQDAIQKMKKLDKILAKKQRREKEIKKQGLEMRIKLWEEIKSAKYSEAWQS 165
+LKE + + QD + K K + L ++ + E + K L+++I+ E K A SE Q
Sbjct: 1060 NRLKEKEHKNQDDLLKEK---ETLIQQLKEELQEKNVTLDVQIQHVVEGKRA-LSELTQG 1115
Query: 166 KEEMENTKKFLSLTAVSEETVGPSHE---EEDTF---SSVFHTQIPPEEYEMQMQKLNKD 219
+ K L T + + V SH E+D S + + +E++ +Q K+
Sbjct: 1116 VTCYKAKIKELE-TILETQKVECSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKN 1174
Query: 220 FTCDVERNESLIKSGKKPFSNT-----------EKIELRGKHNQDFIKRNIELAKESRNP 268
T D+ E +K +N E+ E + + +K + A +R
Sbjct: 1175 -TKDLNVKELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELS-ASSARTQ 1232
Query: 269 VVMVDREKK---------RLVELLKDLDEKDSGLSSSEGDQSGWVVPVKGYELAVTQHQQ 319
+ D ++K +L + K + + +S + ++ +K EL ++Q
Sbjct: 1233 NLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDK--LLRIKINELEKKKNQC 1290
Query: 320 LAEIDIKLQELSAASPTISSFSPRLENRNNQKPDRDGERN-MEVTPGEKILRNTKEQRDL 378
E+D+K + TI +L N+ ++ + ER ++ EKI+ D+
Sbjct: 1291 SQELDMKQR-------TIQQLKEQLNNQKVEEAIQQYERACKDLNVKEKII------EDM 1337
Query: 379 HNRLREIDEKLKMMKENVLESTSCLSE-EQLKCLLDECILKQKSIIKLSSERKKEDIEDV 437
L E E+ ++ ++ VLE+ L E E+L L++ K + +++R ++ E+
Sbjct: 1338 RMTLEE-QEQTQVEQDQVLEAK--LEEVERLATELEKWKEKCNDLETKNNQRSNKEHENN 1394
Query: 438 TPVFPQLSRSIISKLLNESETKV---QKTEVEDADMLESEECEA 478
T V +L+ + L ESE K +K +E+ ML ++ EA
Sbjct: 1395 TDVLGKLTN--LQDELQESEQKYNADRKKWLEEKMMLITQAKEA 1436
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 51.6 bits (122), Expect = 2e-06
Identities = 96/473 (20%), Positives = 188/473 (39%), Gaps = 73/473 (15%)
Query: 69 NDDKQESCSEKIKLAEEGSDEDLDLVQHQI-------ISECSD-EPKLKELDSQLQDAIQ 120
N SC E +KLA EG ED + + +I I+E ++ + K KEL + + +Q
Sbjct: 1562 NQSLSSSC-ESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQ 1620
Query: 121 KMKKLDKILAKKQRREKEIK--KQGLEMRIKLWEEIKSAKYSEAWQSKEEMENTK----- 173
+ + + Q + ++ KQ L +++ E K + ++++EME K
Sbjct: 1621 SYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRK 1680
Query: 174 -------KFLSLTAVSEETVGPSHEEEDTFSSVFHTQIPP--------EEYEMQMQKLNK 218
K L L ++ H DT T + E +M+ + L+K
Sbjct: 1681 FAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSK 1740
Query: 219 DFTCDVERNESLIKSGKKPFSNTEKIELRGKHNQDFIKRNIELAKESRNPVVMVDREKKR 278
F + +SL + K ++ G ++ + N+E ++ N + + +
Sbjct: 1741 KFQSLMSEKDSLSEE-----VQDLKHQIEGNVSK---QANLEATEKHDNQTNVTEEGTQ- 1791
Query: 279 LVELLKDLDEKDSGLSSSEGDQSGWVVPVKGYELAVTQH-----------QQLAEIDIKL 327
+ + +E+DS S+ S V K AV++ QQ+ ++ ++
Sbjct: 1792 --SIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERI 1849
Query: 328 QELSAASPTISSFSPRLENRNN----QKPDRDGERNM---EVTPGEKILRNTKEQRDLHN 380
L FS LEN N Q +DGE M EVT + + +E+
Sbjct: 1850 AGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVT 1909
Query: 381 RLREIDEKLK-MMKENVLESTSCL-----------SEEQLKCLLDECILKQ-KSIIKLSS 427
+L+E E+ K ++E ++ + L ++ Q+K L E +K K +
Sbjct: 1910 KLKETAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELE 1969
Query: 428 ERKKEDIEDVTPVFPQLSRSIISKLLNESETKVQKTEVEDADMLESEECEASK 480
E K++ +++ T V ++ + + K+ + K+ ++ L E+ + K
Sbjct: 1970 EEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVK 2022
Score = 48.1 bits (113), Expect = 2e-05
Identities = 103/491 (20%), Positives = 198/491 (40%), Gaps = 66/491 (13%)
Query: 23 GSRSSNASLEVLSTEPGSFKVDTASNLNSGKEDHSESSNTENRRTSNDDKQESCSEKIKL 82
G+ S A+LE +TE K D +N+ + S TE + + + + +CSE +
Sbjct: 1765 GNVSKQANLE--ATE----KHDNQTNVTE-EGTQSIPGETEEQDSLSMSTRPTCSESVPS 1817
Query: 83 AEEGSDE-DLDLVQHQIISECSDE-PKLKELDSQLQDAIQKMKKLDKILAKKQRR----- 135
A+ + D H I+ + +LKE + L++ QK K+ + L ++
Sbjct: 1818 AKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQI 1877
Query: 136 ----------EKEIKKQGLEMRIKLWEEIKSAKYSEAWQSKEEMENTKKFLSLTAVSEET 185
++E+ K L + ++ EE+ + +E+ + ++ ++ A +
Sbjct: 1878 STKDGELKMLQEEVTKMNL-LNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGS 1936
Query: 186 VGPSHEEEDTFSSVFHTQIPPEEYEMQMQKLNKDFTCDVERNESLIKSGKKPFSNTEKIE 245
+G ++ V QI E E +M+ L K + E + L+K K S K
Sbjct: 1937 IGNYCQD------VTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEY 1990
Query: 246 LRGKHNQDFIKRNIELAKESRNPVVMVDREKKRLVELLKDLDEKDSGLSSSEGDQSGWVV 305
L N AKE + + +E K+L + EK S L +
Sbjct: 1991 LEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERT--------- 2041
Query: 306 PVKGYELAVTQHQQLAEIDIK-----LQELSAASPTISSFSPRLENR---------NNQK 351
VK E T+ Q+ EI + ++ A ++SF L++ +N K
Sbjct: 2042 -VKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLK 2100
Query: 352 PDRDGERNMEVTPGEKILRNTKEQRDLHNRLREIDEKLKMMKENVLESTSCLSEEQLKCL 411
++ + N E + ++ DL RL + +EK K+N+ E L E K
Sbjct: 2101 LKKELQSNKESVKSQM----KQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRRE--KVH 2154
Query: 412 LDECILKQKSIIKLSSERKKEDIEDVTPVFPQLS--RSIISKLLNESE---TKVQKTEVE 466
L+E I + + + + ++ E++ QL+ +S L ++ + + +K E +
Sbjct: 2155 LEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERK 2214
Query: 467 DADMLESEECE 477
+D ++S+E E
Sbjct: 2215 FSDAIQSKEEE 2225
Score = 46.6 bits (109), Expect = 6e-05
Identities = 95/453 (20%), Positives = 178/453 (39%), Gaps = 64/453 (14%)
Query: 107 KLKELDSQLQDAIQKMKKLDKILAKKQRREKEIKKQGLEMRIKLWEEIKSAKYSEAWQSK 166
K++EL L ++ K+D++L +K +R+ E +Q +E + + EI + + Q
Sbjct: 860 KVEELSQALSQKELEITKMDQLLLEK-KRDVETLQQTIEEKDQQVTEISFSMTEKMVQLN 918
Query: 167 EE-------MENTKKFLSLTAVSEETVGPSHEEEDTFSSVFHT---------QIPPEEYE 210
EE ++ K+ L+L + +EE EE++ SS QI EE +
Sbjct: 919 EEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQ 978
Query: 211 MQMQKLNKDFTCDVERNESLIKSGKKPFSNTEKIELRGKHNQDFIKRNIELAKESRNPVV 270
+ L K+ + ++ + + K+ ++E + +D K+ I L++ R V
Sbjct: 979 HEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVE 1038
Query: 271 MVDREKKRLVE-------------LLKDLDEKDSGLSSSEGDQSGWVVPVKGYELAVTQH 317
D+E K E L + + EK+ L D + + ++ V Q
Sbjct: 1039 E-DKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAEEQFQALVKQM 1097
Query: 318 QQLAE-----IDIKLQELSAASPTISSFSPRLENRNNQKPDRDG----ERNMEVTPG--- 365
Q + ID+ E+S I +L N D D + + ++P
Sbjct: 1098 NQTLQDKTNQIDLLQAEISENQAIIQ----KLITSNTDASDGDSVALVKETVVISPPCTG 1153
Query: 366 ----------EKILRNTKEQRDLHNRLREIDEKLKMMKENVLESTSCLSEEQLKCLLDEC 415
EKIL KE+ L +L+E K + + E L EE LK D+
Sbjct: 1154 SSEHWKPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREE-LKQQKDDY 1212
Query: 416 ILKQKSIIKLSSERKKEDIEDVTPVFPQLSRSIISKLLNESETKVQKTEVEDADMLESEE 475
Q+ E+ KE+ E++ QL + + + + Q+ LE
Sbjct: 1213 NRLQEQF----DEQSKEN-ENIGDQLRQLQIQVRESIDGKLPSTDQQESCSSTPGLEEPL 1267
Query: 476 CEASKGYYLTKALTGHNMSEALVTEAENMKCLQ 508
+A++ ++ T+ + N+ + +E+ LQ
Sbjct: 1268 FKATEQHH-TQPVLESNLCPDWPSHSEDASALQ 1299
Score = 45.1 bits (105), Expect = 2e-04
Identities = 91/461 (19%), Positives = 195/461 (42%), Gaps = 68/461 (14%)
Query: 103 SDEPKLKELDSQLQDAIQKM----KKLDKILAKKQRREKEIKKQGLEMRIKLWEEIKSAK 158
S E KE + QLQ+A Q+M +K+ K KQ++ E++++ +R ++ +AK
Sbjct: 1652 STEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTAK 1711
Query: 159 ------YSEAWQSKEEMEN--------TKKFLSL----TAVSEETVGPSHEEEDTFSSVF 200
S KEE+E +KKF SL ++SEE H+ E S
Sbjct: 1712 ECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQA 1771
Query: 201 HTQIPPEEYEMQ---MQKLNKDFTCDVERNESLIKSGKKPFSNTEKIELRGKHNQDFIKR 257
+ + E+++ Q ++ + + E +SL S + S + K + +
Sbjct: 1772 NLE-ATEKHDNQTNVTEEGTQSIPGETEEQDSLSMSTRPTCSESVP---SAKSANPAVSK 1827
Query: 258 NIELAKESRNPVVMVDREKKRLVELLKDLDEKDSGLSSSEGDQSGWV--VPVKGYELAVT 315
+ E N + +D+ K+R+ L ++ + + E +++ + + K EL +
Sbjct: 1828 DFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKML 1887
Query: 316 QHQQLAEIDIKLQELSAASPTISSFSPRLENRNNQKPDRDGERNMEVTPGEKILRNTKEQ 375
Q +++ ++++ Q++ ++ E + +R + E+ I ++
Sbjct: 1888 Q-EEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAEL--NGSIGNYCQDV 1944
Query: 376 RDLHNRLREIDEKLKMMKENVLESTSCLSEEQLKCLLDECILKQKSIIKLSSERKKEDIE 435
D + ++ ++K +K+ V E L EE+ + ++K+K+ K+ SE +KE +E
Sbjct: 1945 TDAQIKNELLESEMKNLKKCVSE----LEEEK------QQLVKEKT--KVESEIRKEYLE 1992
Query: 436 DVTPVFPQLSRSI----ISKLLNESETKVQKTEVE-------------DADMLESEECEA 478
+ + + +LL E + +V++ + + LE + E+
Sbjct: 1993 KIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTES 2052
Query: 479 SKGYYLTKALTGHNMSEALVTEAENMKCLQFSKDVIISDTK 519
K +TK N+++A V + + S V++ DT+
Sbjct: 2053 QKDLEITK----ENLAQA-VEHRKKAQAELASFKVLLDDTQ 2088
Score = 40.0 bits (92), Expect = 0.006
Identities = 97/473 (20%), Positives = 191/473 (40%), Gaps = 55/473 (11%)
Query: 24 SRSSNASLEVLSTEPGSFKVDTASNLNSGKEDHSESSNTENRRTSNDDKQESCSEKIKLA 83
SR S + VL G D E H ES N T QE E++ A
Sbjct: 3 SRLSGLANVVLHELSGDDDTDQNMRAPLDPELHQESDMEFNNTT-----QEDVQERLAYA 57
Query: 84 EEGSDEDLDLVQHQIISECSDEPKLKELDSQLQD----AIQKMKKLDKILAKKQRREKEI 139
E+ E D+++ + + +L++ D LQ+ A K+KKL K+ AK + +
Sbjct: 58 EQLVVELKDIIRQK-------DVQLQQKDEALQEERKAADNKIKKL-KLHAK--AKLTSL 107
Query: 140 KKQGLEMRIKLWEEIKSAKYSEAWQSKEEMENTKKFLSLTAVSEETVGPSHEEEDTFSSV 199
K EM+ + + + SE SK + +T++ + + + + +E++ S
Sbjct: 108 NKYIEEMKAQGGTVLPTEPQSEEQLSKHDKSSTEEEMEIEKIKHKL-----QEKEELIST 162
Query: 200 FHTQIPPEEYEMQMQKLNKDFTCDVERNESLIKSGKKPFSNTEKIELRGKHNQDFIKRNI 259
Q+ + E Q + + V + L K+ F +T + +L + + + +
Sbjct: 163 LQAQLTQAQAEQPAQS-STEMEEFVMMKQQL--QEKEEFISTLQAQL-SQTQAEQAAQQV 218
Query: 260 ELAKESRNPVVMVDREKKRLVELLKDLDEKDSGLSSSEGDQSGWVVPVKGYELAVTQHQQ 319
K++R V + L++L+ D + +E Q V+ K E + +
Sbjct: 219 VREKDARFE-TQVRLHEDELLQLVTQADVE------TEMQQKLRVLQRKLEEHEESLVGR 271
Query: 320 LAEIDIKLQELSAASPTISSFSPRLEN--------RNNQKPDRDGER----NMEVTPGEK 367
+D+ QEL+AA S +L+ RN + +R+ + ME+ E+
Sbjct: 272 AQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMELEVAER 331
Query: 368 ILRNTKEQRDLHNRLREIDEKLKMMKENVLESTSCLSEEQLKCLLDECILKQKSIIKLSS 427
L Q ++H+ L + ++ + E LES E++ K ++E K+ LS
Sbjct: 332 KLSFHNLQEEMHHLLEQFEQAGQAQAE--LESRYSALEQKHKAEMEE-----KTSHILSL 384
Query: 428 ERKKEDIEDVTPVFPQLSRSIISKLLNESETKVQKTEVEDADMLESEECEASK 480
++ ++++ + ++ NE + +T + D L+ + E S+
Sbjct: 385 QKTGQELQSACDALKDQNSKLLQD-KNEQAVQSAQTIQQLEDQLQQKSKEISQ 436
Score = 38.9 bits (89), Expect = 0.013
Identities = 72/335 (21%), Positives = 135/335 (40%), Gaps = 60/335 (17%)
Query: 109 KELDSQLQDAIQKMKKLDKILAKKQRREKEIKKQ--GLEMRIKLWEEIKSAKYSEAWQSK 166
KEL SQL++ LAK + K +K Q L ++ +E K Q +
Sbjct: 2287 KELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQE 2346
Query: 167 EEMENTKKFLSLTAVSEETVGPSHEEEDTFSSVFHTQIPPEEYEMQMQKLNKDFTCDVER 226
+++N+K S E + + +S H EE M+ QK+
Sbjct: 2347 ADIQNSK-------FSYEQLETDLQASRELTSRLH-----EEINMKEQKIIS-------- 2386
Query: 227 NESLIKSGKKPFSNTEKIELRGKHNQDFIKRNIELAKESRNPVVMVDREKK------RLV 280
+ SGK+ ELR +H+++ + L++E +V+ + KK +L+
Sbjct: 2387 ----LLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLM 2442
Query: 281 ELLKDLDEK--------DSGLSSSEGDQSGWVVPVKGYELAVTQHQQ-LAEIDIKLQELS 331
E LK + ++ DS + S Q+ V Y+ +H + E D +QE +
Sbjct: 2443 ETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAA 2502
Query: 332 AAS----PTISSFSPRLENRNNQKPDRDGE-------RNMEVTPGEKILR-----NTKEQ 375
A + I +++ N++ D E N +T + + ++
Sbjct: 2503 AENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQN 2562
Query: 376 RDLHNRLREIDEKLKMMK---ENVLESTSCLSEEQ 407
++L N+ +++EKLK + E++ S + L EE+
Sbjct: 2563 KELENKYAKLEEKLKESEEANEDLRRSFNALQEEK 2597
Score = 35.8 bits (81), Expect = 0.11
Identities = 103/525 (19%), Positives = 208/525 (39%), Gaps = 70/525 (13%)
Query: 105 EPKLKELDSQLQDAIQKMKKLDKILAKKQRREKEIKKQGLEMRIKLWEEIKSAKYSEAWQ 164
E + ++L +LQ+A+ K + K +K+R +E KQ + +L E+ Q
Sbjct: 1170 EKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDE-------Q 1222
Query: 165 SKEEMENTKKFLSLTAVSEETVG---PSHEEEDTFSSVFHTQIP----PEEYEMQ---MQ 214
SKE + L E++ PS +++++ SS + P E++ Q
Sbjct: 1223 SKENENIGDQLRQLQIQVRESIDGKLPSTDQQESCSSTPGLEEPLFKATEQHHTQPVLES 1282
Query: 215 KLNKDFTCDVERNESL--------IKSGKKPFSNTEKIELRGKHNQDFIKRNIELAKESR 266
L D+ E +L IK+ K EK+EL K + EL K+S
Sbjct: 1283 NLCPDWPSHSEDASALQGGTSVAQIKAQLKEI-EAEKVELELKVS----STTSELTKKSE 1337
Query: 267 NPVVMVDREKKRLVEL--LKDLDEKDSGLSSSEGDQSGWVVPVKGYELAVTQHQQLAEID 324
+ ++ K+ +E+ LK + + +E ++ +L + + L E+
Sbjct: 1338 EVFQLQEQINKQGLEIESLKTVSHE------AEVHAESLQQKLESSQLQIAGLEHLRELQ 1391
Query: 325 IKLQELSAASPTISSFSPRLENRNNQKPDRDGERNMEVTPGEKILRNTKEQRDLHNRLRE 384
KL EL L + ++K + E+ E +++ Q L + +E
Sbjct: 1392 PKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQ--LEMQAKE 1449
Query: 385 IDEKLKMMKENVLE--------STSCLSEEQLKCLLDECILKQKSIIKLSSERKKE---- 432
DE++K ++ + E +++Q++ L ++ +K +K + ++E
Sbjct: 1450 HDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLA 1509
Query: 433 ------------DIEDVTPVFPQLSRSIISKLLNESETKVQKTEVEDADMLESEECEASK 480
D+E + +++ +L E + + D +LE++ +S
Sbjct: 1510 RGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSL-SSS 1568
Query: 481 GYYLTKALTG-HNMSEALVTEAENMKCLQFSKDVIISDT-KDYFMSKTLGIGRLKRPSFL 538
L AL G E LV E E++K + ++ + K+ + + + S
Sbjct: 1569 CESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNE 1628
Query: 539 DDPLYGISVSLSSEDQHL--KLSSPE-NTIADEQETKDAAEECKE 580
+ + + ++ E Q L KL S E N E++ ++A +E +E
Sbjct: 1629 AERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEE 1673
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 51.2 bits (121), Expect = 3e-06
Identities = 77/421 (18%), Positives = 177/421 (42%), Gaps = 48/421 (11%)
Query: 54 EDHSESSNTENRRTSNDDKQESCSEKIKLAEEGSDEDLDLVQHQIISECSDEPKLKELDS 113
E + E + +++ E+++ EE E + + + + +E K++E +
Sbjct: 380 EQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQ--VEKMREEKKMQEQEK 437
Query: 114 QLQDAIQKMKKLDKILAK-KQRREKEIKKQGLEMRIKLWEEIKSAKYSEAWQSKEEMENT 172
+ +D +KM++ ++I + K+ RE+E + E +++ EE + + WQ + E
Sbjct: 438 KTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQK 497
Query: 173 KKFLSLTAVSEETVGPSHEEEDTFSSVFHTQIPPEEYEM-QMQKLNKDFTCDVERNESLI 231
+K + E+ +EE ++ +E +M + +K+ + E+ E +
Sbjct: 498 EKLWEQEKMQEQEEKIWEQEEKIRDQ---EEMWGQEKKMWRQEKMREQEDQMWEQEEKMR 554
Query: 232 KSGKKPFSNTEKIELRGKHNQDFIKRNIELAKESRNPVVMVDREKKRLVE--LLKDLDEK 289
+K + E++E K Q+ K+ + ++ R M +REKK E ++++ +EK
Sbjct: 555 DQEQKMWDQEERME---KKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEK 611
Query: 290 ----------------DSGLSSSEGDQSGWVVPVKGYELA---------------VTQHQ 318
+ E ++ W K +E + +H+
Sbjct: 612 MQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHE 671
Query: 319 QLAEIDIKLQELSAASPTISSFSPRLENRNNQKPDRDGERNME-VTPGEKILRNTKEQ-R 376
++ E + K+QE + + + + D++ R E + EK +R +E R
Sbjct: 672 KMQEQE-KMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMR 730
Query: 377 DLHNRLREIDEKLKMMKENVLESTSCLSEEQLKCLLDECILKQKSIIKLSSERKKEDIED 436
+ +++E +EK++ +E + E + E++ K + + +QK KL K ++ E
Sbjct: 731 EQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKE--KLWEHEKMQEQEK 788
Query: 437 V 437
+
Sbjct: 789 I 789
Score = 50.4 bits (119), Expect = 4e-06
Identities = 89/472 (18%), Positives = 192/472 (40%), Gaps = 46/472 (9%)
Query: 11 ISKPAS-NSRIRPGSRSSNASLEVLSTEPGSFKVDTASNLNSGKEDHSESSNTENRRTSN 69
+ P+S N + R S S PG K D A L+ E + ++
Sbjct: 133 LGTPSSFNLALSQAFRGSPLGCVSTSLIPGESK-DLAGRLHHSWHFAGELQRALSAVSTR 191
Query: 70 DDKQESCSEKIKLAEEGSDEDLDLVQHQIISECSDEPKLKELDSQLQDAIQKMKKLDKIL 129
K + E+ L +E L+L ++ I +E +LK+ +++LQ+ K+ +
Sbjct: 192 HKKADRYIEE--LTKERDALSLELYRNTITNE-----ELKKKNAELQE---KLPLAESEK 241
Query: 130 AKKQRREKEIKKQGLEMRIKLWEEIKSAKYSEAWQSKEEMENTKKFLSLTAVSEETVGPS 189
++ Q KE+K++ + L + + E W+ +EE+ +K + EE +
Sbjct: 242 SEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKI---RKQEEKMWRQ 298
Query: 190 HEEEDTFSSVFHTQIPPEEYEMQMQKLNKDFTCDVERNESLIKSGKKPFSNTEKIELRGK 249
E + + E E +M + K + E ++ +K +++ + +
Sbjct: 299 EER------LREQEGKMREQEEKMWRQEK----RLREQEKELREQEKELREQKELREQEE 348
Query: 250 HNQDFIKRNIELAKESRNPVVMVDREKKRLVELLKDLDEKDSGLSSSEGDQSGWVVPVKG 309
Q+ ++ E ++ R + R+++RL E K + E++ + E
Sbjct: 349 QMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQE------------ 396
Query: 310 YELAVTQHQQLAEIDIKLQELSAASPTISSFSPRLENRNNQKPDRDGERNMEVTPGEKIL 369
E Q ++L E + +++E + + + +K RD E M+ E+I
Sbjct: 397 -ERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQ--EEERIR 453
Query: 370 RNTKEQRDLHNRLREIDEKLKMMKENVLESTSCLSEEQLKCLLDECILKQKSIIKLSSE- 428
K+ R+ +RE +EK++ +EN+ E ++Q E + +Q+ + + +
Sbjct: 454 EREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKI 513
Query: 429 -RKKEDIEDVTPVFPQLSRSIISKLLNESETKV----QKTEVEDADMLESEE 475
++E I D ++ Q + + + E E ++ +K ++ M + EE
Sbjct: 514 WEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEE 565
Score = 48.9 bits (115), Expect = 1e-05
Identities = 79/432 (18%), Positives = 180/432 (41%), Gaps = 23/432 (5%)
Query: 53 KEDHSESSNTENRRTSNDDKQESCSEKIKLAEEGSDEDLDLVQHQIISECSDEPKLKELD 112
+E E + R + QE EK+ EE E + + Q E +++E +
Sbjct: 331 REQEKELREQKELREQEEQMQEQ-EEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQE 389
Query: 113 SQLQDAIQKMKKLDKILAKKQRREKEIKKQGLEMRIKLWEEIKSAKYSEAWQSKEE-MEN 171
+++D ++M + D+ L +K+ R +E +K ++ K+ EE K + + + +EE M+
Sbjct: 390 QKMRDQEERMWEQDERLREKEERMREQEKMWEQVE-KMREEKKMQEQEKKTRDQEEKMQE 448
Query: 172 TKKFLSLTAVSEETVGPSHEEEDTFSSVFHTQIPPEEYEMQMQKLNKDFTCDVERNESLI 231
++ E E+E+ EE E Q Q+L + + E +
Sbjct: 449 EERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKE-KLWEQEKMQ 507
Query: 232 KSGKKPFSNTEKI----ELRGKHNQDFIKRNIELAKESRNPVVMVDREKKRLVELLKDLD 287
+ +K + EKI E+ G+ + + + + ++ M ++E+K + K D
Sbjct: 508 EQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQ-----MWEQEEKMRDQEQKMWD 562
Query: 288 EKD-SGLSSSEGDQSGWVVPVKGYELAVTQHQQLAEIDIKLQELSAASPTISSFSPRLEN 346
+++ + E ++ W E + + +++ E + K++E E
Sbjct: 563 QEERMEKKTQEQEKKTW-----DQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEE 617
Query: 347 RNNQKPDRDGERNMEVTPGEKILRNTKEQRDLHNRLREIDEKLKMMKENVLESTSCLSEE 406
+ ++ ++ E+ ++ E+ + +E+ ++L KE + E +E
Sbjct: 618 KMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQE 677
Query: 407 QLKCLLDECILKQKSIIKLSSERKKEDIEDVTPVFPQLSRSIISKLLNESE---TKVQKT 463
+++ +E I +Q+ + K + E++K+ + + R K+ E E + +K
Sbjct: 678 KMQ-EQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKM 736
Query: 464 EVEDADMLESEE 475
+ ++ M E EE
Sbjct: 737 QEQEEKMQEQEE 748
Score = 44.7 bits (104), Expect = 2e-04
Identities = 62/366 (16%), Positives = 156/366 (42%), Gaps = 39/366 (10%)
Query: 78 EKIKLAEEGSDEDLDLVQHQIISECSDEPKLKELDSQLQDAIQKMKKLDKIL-------- 129
E++ EE E ++ Q E +L+E + ++++ +KM + +K L
Sbjct: 272 EEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELR 331
Query: 130 --AKKQRREKEIKKQGLEMR---IKLWEEIKSAKYSE--AWQSKEEM-ENTKKFLSLTAV 181
K+ R +KE+++Q +M+ K+WE+ + + E W+ +E + E K+
Sbjct: 332 EQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQK 391
Query: 182 SEETVGPSHEEEDTFSSVFHTQIPPEEYEMQMQKLNKDFTCDVERNESLIKSGKKPFSNT 241
+ E+++ E+ Q++K+ ++ ++ E + ++
Sbjct: 392 MRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREE--KKMQEQEKKTRDQEEKMQEE 449
Query: 242 EKIELRGK----HNQDFIKRNIELAKESRNPVVMVDRE--KKRLVELLKDLDEKDSGLSS 295
E+I R K + ++ ++ K+ N ++E ++RL E + L E++
Sbjct: 450 ERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQE---KM 506
Query: 296 SEGDQSGWVVPVK--------GYELAVTQHQQLAEIDIKL----QELSAASPTISSFSPR 343
E ++ W K G E + + +++ E + ++ +++ + R
Sbjct: 507 QEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEER 566
Query: 344 LENRNNQKPDRDGERNMEVTPGEKILRNTKEQRDLHNRLREIDEKLKMMKENVLESTSCL 403
+E + ++ + ++ ++ E++ K+ R+ +RE +EK++ +E + E +
Sbjct: 567 MEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKM 626
Query: 404 SEEQLK 409
E++ K
Sbjct: 627 WEQEEK 632
Score = 39.3 bits (90), Expect = 0.010
Identities = 23/122 (18%), Positives = 60/122 (49%), Gaps = 8/122 (6%)
Query: 53 KEDHSESSNTENRRTSNDDKQESCSEKIKLAEEGSDEDLDLVQHQIISECSDEPKLKELD 112
+++ E E + + D ++ E ++ E+ E+ ++++ Q E K++E +
Sbjct: 688 EQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQE 747
Query: 113 SQLQDAIQKMKKLDKILAKKQRREKEIKKQGLEMRIKLWEEIKSAKYSEAWQSKEEMENT 172
++ + +KM + ++ + ++QR E + KLWE K + + W+ +E+M +
Sbjct: 748 EEMWEQEEKMWEQEEKMWEQQRLP--------EQKEKLWEHEKMQEQEKIWEQEEKMRDQ 799
Query: 173 KK 174
++
Sbjct: 800 EE 801
Score = 34.3 bits (77), Expect = 0.32
Identities = 57/336 (16%), Positives = 140/336 (41%), Gaps = 63/336 (18%)
Query: 63 ENRRTSNDDKQESCSEKIKLAEEGSDEDLDLVQHQIISECSDEPKLKELDSQLQDAIQKM 122
E++ ++K +K+ EE ++ Q Q E K++E + ++++ +KM
Sbjct: 543 EDQMWEQEEKMRDQEQKMWDQEERMEKK---TQEQEKKTWDQEEKMRE-EERMREREKKM 598
Query: 123 KKLDKILAKKQRREKEIKKQGLEMRIKLWEEIKSAKYSEA--WQSKEEMENTKKFLSLTA 180
++ ++++ +++ + +E +++ E K+WE+ + + E W+ +E+M
Sbjct: 599 REEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWE--------- 649
Query: 181 VSEETVGPSHEEEDTFSSVFHTQIPPEEYEMQMQKLNKDFTCDVERNESLIKSGKKPFSN 240
EE + + ++ + E+ +MQ Q+ + + E+ E + +K +
Sbjct: 650 -QEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQE---EKIWEQEKMEKKTQEQEKKTWD 705
Query: 241 TEKIELRGKHNQDFIKRNIELAKESRNPVVMVDREKKRLVELLKDLDEKDSGLSSSEGDQ 300
EK+ ++ ++ E K+ R M+ +++++ E + + E++ + E +
Sbjct: 706 QEKMR-----EEESMR---EREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQE--E 755
Query: 301 SGWVVPVKGYELAVTQHQQLAEIDIKLQELSAASPTISSFSPRLENRNNQKPDRDGERNM 360
W K +E Q+L E KL E +
Sbjct: 756 KMWEQEEKMWE-----QQRLPEQKEKLWE-----------------------------HE 781
Query: 361 EVTPGEKILRNTKEQRDLHNRLREIDEKLKMMKENV 396
++ EKI ++ RD ++R +EK++ +E +
Sbjct: 782 KMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKM 817
Score = 33.1 bits (74), Expect = 0.72
Identities = 27/120 (22%), Positives = 60/120 (50%), Gaps = 3/120 (2%)
Query: 51 SGKEDHSESSNTENRRTSNDDKQESCSEKIKLAEEGSDEDLDLVQHQIISECSDEPKLKE 110
S +E + E ++K + EK++ EE E + + Q + ++ +L E
Sbjct: 714 SMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQE-EKMWEQQRLPE 772
Query: 111 LDSQLQDAIQKMKKLDKILAKKQR-REKEIKKQGLEMRIKLWEEIKSAKYSEAWQSKEEM 169
+L + +KM++ +KI ++++ R++E K +G E +++ EE + + W +E+M
Sbjct: 773 QKEKLWEH-EKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKM 831
>gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]
Length = 1417
Score = 51.2 bits (121), Expect = 3e-06
Identities = 108/454 (23%), Positives = 189/454 (41%), Gaps = 73/454 (16%)
Query: 53 KEDHSESSNTENRRTSNDDKQESCSEKIKLAEEGSDEDLDLVQHQIISECSDEPKLKELD 112
K+ H ES + R + K E E +K DE L +Q+Q+ E K+++LD
Sbjct: 801 KQHHLESLD----RLLTESKGEMKKENMK-----KDEALKALQNQVSEETI---KVRQLD 848
Query: 113 SQLQDAIQKMK-KLDKILAKKQRREKEIKKQGLEMRIKLWEEIKSAKYSEAWQSKEEMEN 171
S L+ +++ L+++ K++ EK++KK+ E+ L +E+K +S S++ +
Sbjct: 849 SALEICKEELVLHLNQLEGNKEKFEKQLKKKSEEVYC-LQKELKIKNHSLQETSEQNVIL 907
Query: 172 TKKFLSLTAVSEETVGPSHEEEDTFSSVFHTQIPPEEYEMQMQ------KLNK-DFTCDV 224
+ ++ + E EDT + + Q+ E E+Q Q KL K + C+
Sbjct: 908 QHTLQQQQQMLQQETIRNGELEDTQTKL-EKQVSKLEQELQKQRESSAEKLRKMEEKCES 966
Query: 225 ERNESLIKSGKKPFSNTEKIELRGKHNQDFIKRNIELAKESRNPVVMVDREKKRLVELLK 284
+E+ +K K IEL G Q +K ++ KE + + +K ++ L +
Sbjct: 967 AAHEADLKRQKV-------IELTGTARQ--VKIEMDQYKEE------LSKMEKEIMHLKR 1011
Query: 285 DLDEKDSGLSSSEG--DQSGWVVPVKGY---ELAVTQHQQLAEIDIKLQELSAASPTISS 339
D + K LS + DQ+ + K EL QH E+ LQ+ + +
Sbjct: 1012 DGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQN 1071
Query: 340 FSPRLENRNNQKPD-RDGERNMEVTPGEKILRNTKEQRDLHNRLREIDEKLKMMKENVLE 398
L++ Q + RD + +++ EK +DL LRE +++ K+ +LE
Sbjct: 1072 AHGELKSTLRQLQELRDVLQKAQLSLEEKYTTI----KDLTAELRECKMEIEDKKQELLE 1127
Query: 399 STSCLSEE--QLK------CLLDECILK-----QKSIIKLSSERKKEDIE---------- 435
L E +LK LD I + ++ IIKL +K ++E
Sbjct: 1128 MDQALKERNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIES 1187
Query: 436 ---DVTPVFPQLSRSIISKLLNESETKVQKTEVE 466
+ QL L NE E K E+E
Sbjct: 1188 LNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIE 1221
Score = 37.0 bits (84), Expect = 0.050
Identities = 117/596 (19%), Positives = 234/596 (39%), Gaps = 135/596 (22%)
Query: 2 DIIKGNLDGISKPASNSRIRPGSRSSNASLEVLSTEPGSFKVDTASNLNSGKED------ 55
+I++ NL K N R++ + LE+L + K + N+GKE
Sbjct: 389 EILERNLTNCEK--ENKRLQERCGLYKSELEILKEKLRQLKEEN----NNGKEKLRIMAV 442
Query: 56 -HSE--SSNTENRRT------SNDDKQESCSEKIKLAEEGSD---------EDLDLVQHQ 97
+SE + TE+R++ ++K E +K L E + E LDL Q +
Sbjct: 443 KNSEVMAQLTESRQSILKLESELENKDEILRDKFSLMNENRELKVRVAAQNERLDLCQQE 502
Query: 98 IISECSDEPKLKELDSQL------------------------QDAIQKMKKLDKILAKKQ 133
I S + L+++ SQL +D + +K++ +
Sbjct: 503 IESSRVELRSLEKIISQLPLKRELFGFKSYLSKYQMSSFSNKEDRCIGCCEANKLVISEL 562
Query: 134 RREKEIKKQGLEMRIKLWEEIKSAKYSEAWQSKEEMENTKKFLSLTAVSEETVGPSHEEE 193
R + IK+ ++ KL + + + S++ + + + + K SL +G E
Sbjct: 563 RIKLAIKEAEIQ---KLHANLTANQLSQSLITCNDSQESSKLSSL-ETEPVKLGGHQVAE 618
Query: 194 DTFSSVFHTQIPPEEYEMQMQKL-----------------NKDFTCDVERNESLIKSGKK 236
HT ++YE + Q+L N D ++ S + ++
Sbjct: 619 SVKDQNQHTM--NKQYEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQE 676
Query: 237 PF----SNTEKIELRGKHNQDFIKRNIELAKESRNPVVMVDREKKRLVELLKDLDEKDSG 292
SN+ K+E + + L K+ +V + EL ++L EK+
Sbjct: 677 ELLEKASNSSKLE---SEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEK 733
Query: 293 LSSSEGD-----QSGWVVPVKGYELAVTQHQQL--------AEIDIKLQELSAASPTISS 339
+ S E + + + K ++ + QH+++ A+++ K Q+ T+S
Sbjct: 734 IRSLETNINTEHEKICLAFEKAKKIHLEQHKEMEKQIERLEAQLEKKDQQFKEQEKTMSM 793
Query: 340 FSP-------RLENRNNQKPDRDGE---RNMEVTPGEKILRNTKEQRDLHNRLREIDEKL 389
LE+ + + GE NM+ K L+N + + ++R++D L
Sbjct: 794 LQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETI--KVRQLDSAL 851
Query: 390 KMMKE------NVLESTSCLSEEQLK-------CLLDECILK---------QKSIIKLSS 427
++ KE N LE E+QLK CL E +K Q I++ +
Sbjct: 852 EICKEELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTL 911
Query: 428 ERKKEDIEDVTPVFPQL--SRSIISKLLNESETKVQKTEVEDADMLE--SEECEAS 479
+++++ ++ T +L +++ + K +++ E ++QK A+ L E+CE++
Sbjct: 912 QQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCESA 967
Score = 35.8 bits (81), Expect = 0.11
Identities = 62/295 (21%), Positives = 114/295 (38%), Gaps = 60/295 (20%)
Query: 182 SEETVGPSHEEEDTFSSVFHTQIPPEEYEMQMQKL-----------NKDFTCDVERNESL 230
S + +EEE ++V + + E +Q L N D+ + R+E L
Sbjct: 123 SSDYYNKDNEEESLLANVASLRHELKITEWSLQSLGEELSSVSPSENSDYAPNPSRSEKL 182
Query: 231 IKSGK---------KPFSNTEKIELRGKHNQDFIKRNIELAKESRNPVVMVDREKKRLVE 281
I + P+ N KI + DF K+ + S PV D+E K L E
Sbjct: 183 ILDVQPSHPGLLNYSPYENVCKIS---GSSTDFQKKPRDKMFSSSAPV---DQEIKSLRE 236
Query: 282 LLKDLDEKDSGLSSSEGDQSGWVVPVKGYELAVTQHQQLAEIDIKLQELSAASPTISSFS 341
L L ++++ L + + + +TQ + + Q+ +A+ P +
Sbjct: 237 KLNKLRQQNACLVTQN---HSLMTKFESIHFELTQSRAKVSMLESAQQQAASVPILEEQI 293
Query: 342 PRLENRNNQKPDRDGERNMEVTPGEKILRNTKEQRDLHNRLREIDEKLKMMKENVLESTS 401
LE EV+ +K+LR E + KL+ ++ V+E
Sbjct: 294 INLE--------------AEVSAQDKVLR-------------EAENKLEQSQKMVIEKEQ 326
Query: 402 CLSEEQLKCL-LDECILKQKSIIKLSSERKKE---DIEDVTPVFPQLSRSIISKL 452
L E + +C+ L +L+Q K + ++ E + E+++ F Q + + KL
Sbjct: 327 SLQESKEECIKLKVDLLEQTKQGKRAERQRNEALYNAEELSKAFQQYKKKVAEKL 381
Score = 32.3 bits (72), Expect = 1.2
Identities = 47/242 (19%), Positives = 103/242 (42%), Gaps = 16/242 (6%)
Query: 120 QKMKKLDKILAKKQRREKEIKKQGLEMRIKLWEEIKSAKYSE--AWQSKEEMENTKKFLS 177
QK+ KL+ L K + KE KQ + KL + + E Q+++E+ KK +
Sbjct: 1162 QKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIE 1221
Query: 178 LTAV-SEETVGPSHEEEDTFSSVFHTQIP-PEEYEMQMQKLNKDFTCDVERNESLIKSGK 235
T +E E+E ++ + I +E + +++ T E +++ +
Sbjct: 1222 RTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQR 1281
Query: 236 KPFSNTEKIELRGKHNQDFIKRNIELAKESRNPVVMVDREKKRLVELLKDLDEKDSGLS- 294
+ + ++E + +++ LA+E V + R+ +K L + L
Sbjct: 1282 EIERLSSELEDMKQLSKEKDAHGNHLAEELGASKVREAHLEARMQAEIKKLSAEVESLKE 1341
Query: 295 -------SSEGDQSGWVVPVKGYELAVTQ-HQQLAEIDIKLQELSAASPTISSFSPRLEN 346
S + + + W + + +V Q ++QL + ++L+E A T+S+ ++++
Sbjct: 1342 AYHMEMISHQENHAKWKISADSQKSSVQQLNEQLEKAKLELEE---AQDTVSNLHQQVQD 1398
Query: 347 RN 348
RN
Sbjct: 1399 RN 1400
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 50.4 bits (119), Expect = 4e-06
Identities = 70/391 (17%), Positives = 163/391 (41%), Gaps = 64/391 (16%)
Query: 53 KEDHSESSNTENRRTSNDDKQESCSEKIKLAEEGSDEDLDLVQHQIISECSDEPKLKELD 112
+E + E + ++ EK++ EE E + ++ Q E K++EL+
Sbjct: 385 REQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELE 444
Query: 113 SQL------QDAIQKMKKLDKILAKKQRREKEIKKQGLEMRIKLWEEIKSAKYSEAWQSK 166
++ ++ +K ++ +KI +++R+E+E K E +I+ EE + + W+ +
Sbjct: 445 EKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQE 504
Query: 167 EEMENTKKFLSLTAVSEETVGPSHEEEDTFSSVFHTQIPPEEYEMQMQKLNKDFTCDVER 226
E++ +K + EE EE Q EE Q +K++ E+
Sbjct: 505 EKIHEQEK------IREEEKRQEQEEMWRQEEKIREQ---EEIWRQKEKIH-------EQ 548
Query: 227 NESLIKSGKKPFSNTEKIELRGKHNQDFIKRNIELAKESRNPVVMVDREKKRLVELLKDL 286
E + K +K + EK+ H+Q+ ++ R V R+++++ E + +
Sbjct: 549 EEKIRKQEEKMWRQEEKM-----HDQE---------EKIREQEEKVWRQEEKIREQEEKI 594
Query: 287 DEKDSGLSSSEGDQSGWVVPVKGYELAVTQHQQLAEIDIKLQELSAASPTISSFSPRLEN 346
E++ + E E+ Q +++ E + K+ E E
Sbjct: 595 REQEEKIREQE-------------EMTQEQEEKMGEQEEKMCE--------------QEE 627
Query: 347 RNNQKPDRDGERNMEVTPGEKILRNTKEQ-RDLHNRLREIDEKLKMMKENVLESTSCLSE 405
+ ++ ++ + ++ EK +R +E+ R+ ++E +EK+ +E + E + E
Sbjct: 628 KMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 687
Query: 406 EQLKCLLDECILKQKSIIKLSSERKKEDIED 436
++ K E + ++ + E K ++ ++
Sbjct: 688 QEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 718
Score = 41.6 bits (96), Expect = 0.002
Identities = 78/405 (19%), Positives = 169/405 (41%), Gaps = 60/405 (14%)
Query: 74 ESCSEKIKLAEEGSDEDLDLVQHQIISECSDEPKLKELDSQLQDAIQKMKKLDKILAKKQ 133
+S S K++ E ++ L Q Q E K++E + ++Q+ +K+++ ++ K
Sbjct: 336 QSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEE----KI 391
Query: 134 RREKEIKKQGLEMRIKLWEEIKSAKYSEA--WQSKEEMENTKKFLSLTAVSEETVGPSHE 191
R ++E ++ EM +WE+ + + E W+ +E+M EE + E
Sbjct: 392 REQEEKMRRQEEM---MWEKEEKMRRQEEMMWEKEEKMRR----------QEEMMWEKEE 438
Query: 192 EEDTFSSVFHTQIPPEEYEMQMQKLNKDFTCDVERNESLIKSGKKPFSNTEKIELRGKHN 251
+ H Q E E + Q+ K + E + K + EKI +
Sbjct: 439 KIRELEEKMHEQEKIREQEEKRQEEEK-----IREQEKRQEQEAKMWRQEEKI----REQ 489
Query: 252 QDFIKRNIELAKESRNPVVMVDREKKRLVELLKDLDEKDSGLSSSEGDQSGWVVPVKGYE 311
++ I+ E K R + ++EK R E ++ +E + W K +E
Sbjct: 490 EEKIREQEE--KMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHE 547
Query: 312 LAVTQHQQLAEIDIKLQELSAASPTISSFSPRLENRNNQKPDRDGERNMEVTPGEKILRN 371
Q +++ + + K+ R E + + + ++ E+ +V E+ +R
Sbjct: 548 ----QEEKIRKQEEKMW--------------RQEEKMHDQEEKIREQEEKVWRQEEKIRE 589
Query: 372 TKEQ-RDLHNRLREIDEKLKMMKENVLESTSCLSEEQLKCLLDECILKQKSIIKLSSERK 430
+E+ R+ ++RE +E + +E + E +E+ C +E + +Q+ ++ E+
Sbjct: 590 QEEKIREQEEKIREQEEMTQEQEEKMGE------QEEKMCEQEEKMQEQEEKMRRQEEKI 643
Query: 431 KEDIEDVTPVFPQLSRSIISKLLNESETKVQKTEVEDADMLESEE 475
+E + + ++ +++ E E K+ + E + M E EE
Sbjct: 644 REQEKKIREQEEKIREQ--EEMMQEQEEKMWEQEEK---MCEQEE 683
Score = 32.7 bits (73), Expect = 0.94
Identities = 38/229 (16%), Positives = 98/229 (42%), Gaps = 14/229 (6%)
Query: 249 KHNQDFIKRNIELAKESRNPVVMVDREKKRLVELLKDLDEKDSGLSSSEGDQSGWVVPVK 308
++ ++ K L+ E + + K++ +L + L +S S + + ++
Sbjct: 254 RYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLE 313
Query: 309 GYELAVTQHQQLAEIDIKLQELSAASPTISSFSPRLE--NRNNQKPDRDGERNMEVTPGE 366
+L + Q Q AE D +EL + S + + E NR NQ+ + E
Sbjct: 314 RAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQE------------E 361
Query: 367 KILRNTKEQRDLHNRLREIDEKLKMMKENVLESTSCLSEEQLKCLLDECILKQKSIIKLS 426
K+ R ++ ++ +++E +EK++ +E + E + ++ E ++++ +
Sbjct: 362 KMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE 421
Query: 427 SERKKEDIEDVTPVFPQLSRSIISKLLNESETKVQKTEVEDADMLESEE 475
E K E++ + R + K+ + + + Q+ + ++ + + +E
Sbjct: 422 KEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE 470
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 50.4 bits (119), Expect = 4e-06
Identities = 103/485 (21%), Positives = 208/485 (42%), Gaps = 57/485 (11%)
Query: 42 KVDTASNLNSGKEDHSESSNTENRRTSNDDKQESCSEKIKLAEEGSDEDLDLVQHQIISE 101
+V+T+ LNS E H++ S+ E+ + +S E+ LD+ +S
Sbjct: 1859 RVETSEGLNSDLEMHADKSSREDIGDNVAKVNDSWKERF----------LDVENE--LSR 1906
Query: 102 CSDEPKLKELDSQLQDAIQKMKKLDKILAKKQRREKEIKKQGLEMRIKLWEEIKSAKYSE 161
E E ++ +A ++ + +K+ +K K+ ++ + L EE+ S SE
Sbjct: 1907 IRSEKASIEHEALYLEADLEVVQTEKLCLEKDNENKQ------KVIVCLEEEL-SVVTSE 1959
Query: 162 AWQSKEEMEN-TKKFLSLTAVSEETVGPSHEEEDTFSSVFHTQIPPEEYEMQMQKLNKDF 220
Q + E++ +KK +L +SE+ + E E S H E + +L +
Sbjct: 1960 RNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTL 2019
Query: 221 TCDVERNESLIKSGKKPFSNTEKIELRGKHNQDFIKRNIELAKESRNPVVMVDREKKRLV 280
+ DV +E L K EK++ K +Q EL N + +++EK+ LV
Sbjct: 2020 SSDV--SELL----KDKTHLQEKLQSLEKDSQALSLTKCEL----ENQIAQLNKEKELLV 2069
Query: 281 ELLKDLDEKDSGLSSSEGDQSGWVVPVKGYELAVTQHQQLA-EIDIKLQELSAASPTISS 339
K+ + + LS S+ ++ + K E A+ + + A + +E+ I
Sbjct: 2070 ---KESESLQARLSESDYEK---LNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEK 2123
Query: 340 FSPRLENRNNQKPDRDGERNMEVTPGEKILRNTKEQRDLHNRLREIDEKLKMMKEN---- 395
R+E D ++ + + EK+ +E L +++ ++ +L+M +EN
Sbjct: 2124 LRVRIE--------ADEKKQLHI--AEKLKERERENDSLKDKVENLERELQMSEENQELV 2173
Query: 396 VLESTSCLSE-EQLKCLLDECILKQKSIIKLSSERKKEDIEDVTPVF--PQLSRSIISKL 452
+L++ + +E E LK ++E + + + +L + + E++T Q S + KL
Sbjct: 2174 ILDAENSKAEVETLKTQIEE-MARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKL 2232
Query: 453 LNESETKVQKTEVEDADMLESEECEASKGYYLTKALTGHNMSEALVTEAENMKCLQFSKD 512
L+ ++ ++ E E A++ EE + + + + AL + E MK + S D
Sbjct: 2233 LSSFKSLLE--EKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLD 2290
Query: 513 VIISD 517
I +
Sbjct: 2291 PPIEE 2295
Score = 46.2 bits (108), Expect = 8e-05
Identities = 75/401 (18%), Positives = 175/401 (43%), Gaps = 43/401 (10%)
Query: 53 KEDHSESSNTENRRT--SNDDKQESC-----------SEKIKLAEEGSDEDLDLV----Q 95
+E+H ++ E R D+K++ C ++ +K E + +L++ +
Sbjct: 2294 EEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQE 2353
Query: 96 HQIISECSDEPKLKELDSQLQDAIQKMKKLD----KILAKKQRREKEIKKQGLEMRIKLW 151
H + + + +++ L ++++ Q ++ L+ I ++K+ E++K+ + RI
Sbjct: 2354 HAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKE--QERISEL 2411
Query: 152 EEIKSAKYSEAWQSKEEMENTKKFLSLTAVSEETVGPSHEEEDTFSSVFHTQIPPEEYEM 211
E I S+ + Q KE+ + K S TA+ E + +E + + H E +
Sbjct: 2412 EIINSS-FENILQEKEQEKVQMKEKSSTAM--EMLQTQLKELNERVAALHND--QEACKA 2466
Query: 212 QMQKLNKDFTCDVERNESLIKSGKKPFSNTEKIELRGKHNQDFIKRNIELAKESRNPVVM 271
+ Q L+ C +E ++ + G N + Q + I+ ++ + +
Sbjct: 2467 KEQNLSSQVEC-LELEKAQLLQGLDEAKNNYIVL------QSSVNGLIQEVEDGKQKLEK 2519
Query: 272 VDREKKRLVELLKDLDEKDSGLSSSEGDQSGWVVPVKGYELAVTQHQQLAEIDIKLQELS 331
D E RL ++D ++ S LS EG+ W E + E++ K+Q L
Sbjct: 2520 KDEEISRLKNQIQDQEQLVSKLSQVEGEHQLW------KEQNLELRNLTVELEQKIQVLQ 2573
Query: 332 AASPTISSFSPRLENR-NNQKPDRDGERNMEVTPGEKILRNTKEQRDLHNRLREIDEKLK 390
+ + ++ L++ N + + + + +++ EK+ + T ++ +L + E+ +K
Sbjct: 2574 SKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTA 2633
Query: 391 MMKENVLESTSCLSEEQLKCLLDECILKQKSIIKLSSERKK 431
++E + + L+ E L+ LL+E + + +L+ E +
Sbjct: 2634 ELQEELSGEKNRLAGE-LQLLLEEIKSSKDQLKELTLENSE 2673
Score = 40.8 bits (94), Expect = 0.003
Identities = 68/401 (16%), Positives = 162/401 (40%), Gaps = 39/401 (9%)
Query: 53 KEDHSESSNTENRRTSNDDKQESCSEKIKLAEEGSDEDLDLVQHQIISECSDE--PKLKE 110
KE + + +R+ QE K +L +E H ++ D+ ++
Sbjct: 392 KEKEFQEELSRQQRSFQTLDQECIQMKARLTQELQQAKN---MHNVLQAELDKLTSVKQQ 448
Query: 111 LDSQLQDAIQKMKKLDKILAKKQRREKEIKKQGLEMRIK--LWEEIKSAKYSEAWQSKEE 168
L++ L++ QK+ + ++ Q +E E+++ EM+ + L + K E + E
Sbjct: 449 LENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAE 508
Query: 169 MENTKKFLSLTAVSEETVGPSHEEEDTFSSVFHTQIPPEEYEMQMQKLNKDFTCDVERNE 228
++N K+ L+ + E + + ++T +I +E + ++KL K D+E+
Sbjct: 509 LKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKL-KLAVADLEKQR 567
Query: 229 SLIKSGKKPFSNTEKIELRGKHNQDFIKRNIELAKESRNPVVMVDREKKRLVELLKD--- 285
+ + ++ R H + + + KES+ + ++ +KK EL ++
Sbjct: 568 D---------CSQDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEYEELKEEKTL 618
Query: 286 ----LDEKDSGLSSSEGDQSGWVVPVKGYELAV-TQHQQLAEIDIKLQELSAASPTISSF 340
E + L+ E ++ + E + TQ + E + +++ L +S
Sbjct: 619 FSCWKSENEKLLTQMESEKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVE 678
Query: 341 SPRLENRNNQKP---DRDGERNMEVTPGEKILRNTKEQRDLHN----------RLREIDE 387
L N + K + ME+ + + K Q+++ N ++ +++
Sbjct: 679 IRNLHNVLDSKSVEVETQKLAYMELQQKAE-FSDQKHQKEIENMCLKTSQLTGQVEDLEH 737
Query: 388 KLKMMKENVLESTSCLSEEQLKCLLDECILKQKSIIKLSSE 428
KL+++ +++ C + + +LK K +++E
Sbjct: 738 KLQLLSNEIMDKDRCYQDLHAEYESLRDLLKSKDASLVTNE 778
Score = 40.4 bits (93), Expect = 0.005
Identities = 71/288 (24%), Positives = 124/288 (43%), Gaps = 36/288 (12%)
Query: 25 RSSNASLE-VLSTEPGSFKVDTASNLNSGKEDHSESSNTENRRTSND-----DKQESCSE 78
+S NASL+ L S+K + + L K D N+ T+ + + E +
Sbjct: 2573 QSKNASLQDTLEVLQSSYK-NLENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQK 2631
Query: 79 KIKLAEEGSDE------DLDLVQHQIISECSDEPKL--------KELDSQLQDAIQKMKK 124
+L EE S E +L L+ +I S +L K LD +D ++K K
Sbjct: 2632 TAELQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGK 2691
Query: 125 LDKILAKKQRR--EKEIKKQGLEMRIKLWEEIKSAKYSEAWQSKEEMENTKKF-LSLTAV 181
+ + +A+ Q R E E K Q L + E++ Y E SKEE +++K + L
Sbjct: 2692 VREEIAEYQLRLHEAEKKHQALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKS 2751
Query: 182 SEETVGPS-HEEEDTFSSVFHTQIPPEEYEMQMQKLNKDFTCDVERNESLIKSGKKPFSN 240
S+E + S + T++ +Y Q++K N+ + + LIKS K+
Sbjct: 2752 SKEELNNSLKATTQILEELKKTKMDNLKYVNQLKKENERAQ---GKMKLLIKSCKQ--LE 2806
Query: 241 TEKIELRGKHNQDFIKRNIELAKESRNPVVMVDREKKRLVELLKDLDE 288
EK L+ + +Q ++ A+E + ++D + L +K+L E
Sbjct: 2807 EEKEILQKELSQ------LQAAQEKQKTGTVMDTKVDELTTEIKELKE 2848
Score = 40.0 bits (92), Expect = 0.006
Identities = 92/426 (21%), Positives = 187/426 (43%), Gaps = 57/426 (13%)
Query: 63 ENRRTSNDDKQESCSEKIKLAEEGSDEDLDLVQ-HQ-IISECSDE-PKLKELDSQLQDAI 119
E+++ N D Q+ C E +++ E + + Q HQ ++E S KL+E S Q+ +
Sbjct: 840 ESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFVAETSQRISKLQEDTSAHQNVV 899
Query: 120 QKMKKLDKILAKKQRREKEIKKQGLEMRIKLWEEIKSAKYSEAWQSKEEMENTKKFLSLT 179
+ L+ + +EKE+ Q L ++ E + A+ E +S +E++ K L L
Sbjct: 900 AET------LSALENKEKEL--QLLNDKV----ETEQAEIQELKKSNHLLEDSLKELQLL 947
Query: 180 AVSEETVGPSHEEEDTFSSVFHTQIPPEEYEMQMQK-----LNKDFTCDVERNESL---I 231
+ ET+ +E + S+ +I E K LN++ ++++ES I
Sbjct: 948 S---ETLSLEKKEMSSIISLNKREIEELTQENGTLKEINASLNQEKMNLIQKSESFANYI 1004
Query: 232 KSGKKPFSNTEKIELRGKHNQDFIKRNIELAKESRNPVVMVDREKKRLVELLKDLDEKDS 291
+K S EL ++ Q+ + ++ +E+ N + ++ K E L+ +
Sbjct: 1005 DEREKSIS-----ELSDQYKQEKLIL-LQRCEETGNAYEDLSQKYKAAQEKNSKLECLLN 1058
Query: 292 GLSSSEGDQSGWVVPVKGYELAVTQHQQ----LAEIDIKLQELSAASPTISSF--SPRLE 345
+S ++ + +K E +HQ+ LA + + Q L T+ S +
Sbjct: 1059 ECTSLCENRKNELEQLK--EAFAKEHQEFLTKLAFAEERNQNLMLELETVQQALRSEMTD 1116
Query: 346 NRNNQKPDRDGERNMEVTPGEKILRNTKEQRDLHNRLREIDEKLKMMK-----ENVLEST 400
N+NN K + G + +T E+ K Q+++++ L+E ++ +K+MK +N+
Sbjct: 1117 NQNNSKSEAGGLKQEIMTLKEE---QNKMQKEVNDLLQENEQLMKVMKTKHECQNLESEP 1173
Query: 401 SCLSEEQLKCLLDECILKQKSIIKLSSERKKEDIEDVTPVFPQLSRSIISKLLNESETKV 460
S ++ + ++C K ++ E K+ ++ QL +L E K+
Sbjct: 1174 IRNSVKERESERNQCNFKP----QMDLEVKEISLDSYNAQLVQL-----EAMLRNKELKL 1224
Query: 461 QKTEVE 466
Q++E E
Sbjct: 1225 QESEKE 1230
Score = 39.3 bits (90), Expect = 0.010
Identities = 84/483 (17%), Positives = 195/483 (40%), Gaps = 60/483 (12%)
Query: 1 MDIIKGNLDGISKPASNSRIRPGSRSSNASLEVLSTEPGSFKVDTASNLNSGKEDHSESS 60
++II + + I + +++ +SS A +E+L T+ A+ N + ++
Sbjct: 2411 LEIINSSFENILQEKEQEKVQMKEKSSTA-MEMLQTQLKELNERVAALHNDQEACKAKEQ 2469
Query: 61 NTENRRTSNDDKQESCSEKIKLAE-EGSDED------LDLVQHQIISECSD--------E 105
N + Q C E K +G DE L + +I E D +
Sbjct: 2470 NLSS--------QVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKD 2521
Query: 106 PKLKELDSQLQDAIQKMKKLDKILAKKQR-REKEIKKQGLEMRIKLWEEIKSAKYSEAWQ 164
++ L +Q+QD Q + KL ++ + Q +E+ ++ + L + ++ ++ +K +
Sbjct: 2522 EEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQD 2581
Query: 165 SKEEMENTKKFLSLTAVSEETVGPSHEEEDTFSSVFHTQIPPEEYEMQMQKLNKDFTCDV 224
+ E ++++ K L + S E+ + T++ E +EM +
Sbjct: 2582 TLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKT--------A 2633
Query: 225 ERNESLIKSGKKPFSNTEKIELRGKHNQDFIKRNIELAKESRNPVVMVDREKKRLVELL- 283
E E L + EK L G+ + I+ +K+ + + + E K+ ++ +
Sbjct: 2634 ELQEEL---------SGEKNRLAGE--LQLLLEEIKSSKDQLKELTLENSELKKSLDCMH 2682
Query: 284 KDLDEKDSGLSSSEGDQSGWVVPVKGYELAV---TQHQQLAEIDIKLQELSAASPTISSF 340
KD EK+ + + + + A+ T Q EI ++L++ +SS
Sbjct: 2683 KDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTNKQYEVEIQTYREKLTSKEECLSSQ 2742
Query: 341 SPRLENRNNQKPDRDGERNMEVTPGEKILRNTKEQRDLHNRLREIDEKLKMMKENVLEST 400
++ + K + + E++ + + N+L++ +E+ + + +++S
Sbjct: 2743 KLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSC 2802
Query: 401 SCLSEEQLKCLLDECILKQKSIIKLSSERKK------EDIEDVTPVFPQLSRSIISKLLN 454
L EE+ E + K+ S ++ + E++K ++++T +L ++ K
Sbjct: 2803 KQLEEEK------EILQKELSQLQAAQEKQKTGTVMDTKVDELTTEIKELKETLEEKTKE 2856
Query: 455 ESE 457
E
Sbjct: 2857 ADE 2859
Score = 35.4 bits (80), Expect = 0.15
Identities = 75/398 (18%), Positives = 167/398 (41%), Gaps = 56/398 (14%)
Query: 100 SECSDEPKLKELDSQLQDAIQKMKKLDKILAKKQRREKEIKKQGLEMRIKLWEEIKSAKY 159
+ CS E K+KE + + Q+ L+++QR + + ++ ++M+ +L +E++ AK
Sbjct: 381 ARCSLEQKIKEKEKEFQEE----------LSRQQRSFQTLDQECIQMKARLTQELQQAKN 430
Query: 160 SEAWQSKEEMENTKKFLSLTAVSEETVGPSHEEEDTFSSVFHTQIPPEEYEMQMQKLNKD 219
E + T L EE E F + +QI E M+++ K+
Sbjct: 431 MHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQA---SQIKENELRRSMEEMKKE 487
Query: 220 FTC----------DVERNESLIKSGKKPFSNTEKI--ELRGKH-NQDFIKRNIELAKESR 266
+V E+ +K+ K+ + ++ E++ K+ +Q+ + R+++ +
Sbjct: 488 NNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQ 547
Query: 267 NPVVMVDREKKRLVELLKDLDEKDSGLSSSEGDQSGWVVPVKGYELAVTQHQQ---LAEI 323
+ +++ K + +L K D L E + +L+ T+ + L+ +
Sbjct: 548 ENSLTLEKLKLAVADLEKQRDCSQDLLKKREHH-----IEQLNDKLSKTEKESKALLSAL 602
Query: 324 DIK---LQELSAASPTISSFSPRLENRNNQKPDRDGERNMEVTPGEKILRNTK-EQRDLH 379
++K +EL S + E Q ++ E L+ + + + +
Sbjct: 603 ELKKKEYEELKEEKTLFSCWKSENEKLLTQMESEKENLQSKINHLETCLKTQQIKSHEYN 662
Query: 380 NRLREIDEKLKMMK------ENVLESTSCLSEEQLKCLLDECILKQKSIIKLSSERKKED 433
R+R ++ + + NVL+S S E Q ++ L+QK+ + S ++ +++
Sbjct: 663 ERVRTLEMDRENLSVEIRNLHNVLDSKSVEVETQKLAYME---LQQKA--EFSDQKHQKE 717
Query: 434 IEDVTPVFPQLSRSIISKLLNESETKVQ--KTEVEDAD 469
IE++ L S ++ + + E K+Q E+ D D
Sbjct: 718 IENMC-----LKTSQLTGQVEDLEHKLQLLSNEIMDKD 750
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 50.1 bits (118), Expect = 6e-06
Identities = 96/478 (20%), Positives = 193/478 (40%), Gaps = 72/478 (15%)
Query: 53 KEDHSESSNTENRRTSNDDKQESCSEKIKLAEEG----------SDEDLDLVQHQIISEC 102
K +E + R ++++ E+ +LA+E + +D ++ Q +
Sbjct: 1580 KRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQ 1639
Query: 103 SDEP---KLKELDSQLQDAIQKMKKLDKILAKKQRREKEIKKQGLEMR------IKLWEE 153
+E + ++L + + QK KKL K K R E+++ K+G ++ + EE
Sbjct: 1640 KEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEE 1699
Query: 154 IKSAKYSEAWQSKE---EMENTKKFLSLTAVSEETVGPSHEEEDTFSSVFHTQIPPEEYE 210
+ + + WQ KE E+E + + + EE + + EE E
Sbjct: 1700 LPQREQNLDWQEKELAQELEELEWDMEELSWKEEEL--NQEEGKLVEEKKKLAEEEEALA 1757
Query: 211 MQMQKLNKDFTCDVERNESLIKSGKKPFSNTEKI----ELRGKHNQDFIKRNIELAK--- 263
Q +KL+++ T + E LI+ +K + EK+ E G+ + I++ ++LA+
Sbjct: 1758 WQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRE 1817
Query: 264 ------ESRNPVVMVDREKKRLVELLKDLDEKDSGLSSSEGDQSGWVVPVKGYELAVTQH 317
E M+ +KK L + K+L ++ L+ + + + E
Sbjct: 1818 RWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENL------LYNKERLTHSK 1871
Query: 318 QQLAEIDIKLQELSAASPTISSFSPRLENRNNQKPDRDGERNMEVTPGEKILRNTKEQRD 377
+QL ++ KL + ++E + Q E+ + EK+ K+
Sbjct: 1872 KQLVQVKNKL-------GMFNKILAQVEEKLTQ------EKETVIKKKEKLAETEKKLVQ 1918
Query: 378 LHNRLREIDEKLKMMKENV-LESTSCLSEEQLKCLLDECILKQKSIIKLSSERKKED--- 433
+ + L + EKL K + LE +++L+ LD I K++ + L +R E+
Sbjct: 1919 VEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELD--IAKEEKALNLEMKRLAEEKMR 1976
Query: 434 -IEDVTPV----FPQLSR-----SIISKLLNESETKVQKTEVEDADMLESEECEASKG 481
+E + P+ SR + +L + +K + + +L EE E +KG
Sbjct: 1977 LVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKILLHEDRILAMEESEIAKG 2034
Score = 46.6 bits (109), Expect = 6e-05
Identities = 83/405 (20%), Positives = 165/405 (40%), Gaps = 47/405 (11%)
Query: 49 LNSGKEDHS--ESSNTENRRTSNDDKQESCSEKIKLAEEGSDEDLDLVQHQIIS-ECSDE 105
L GKE S E+ T +R +QE K+ L +E + L + +I++ E S+
Sbjct: 1977 LVEGKETLSKGETPETSRQRKMTQVEQELFERKLSL-----EEKILLHEDRILAMEESEI 2031
Query: 106 PKLK-ELDSQLQDAIQKMKKLDKILAKKQRREKEIKKQGLEMRIKLWEEIKSAKYSEAWQ 164
K K E + +Q +KL K K ++ + + K+ ++ K+ + ++ E
Sbjct: 2032 AKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLN-KILKALQKLTRDERKL 2090
Query: 165 SKEEMENTKKFLSLTAVSEETVGPSHEEEDTFSSVFHTQIPPEEYEMQMQKLNKDFTCDV 224
++EE++ TK +L V E + + D I ++ + +L KD
Sbjct: 2091 TQEEIKMTKMKRALF-VKERRLSIEQSKLD---------IKEWDFSEKRSELTKDEKKLA 2140
Query: 225 ERNESLIKSGKKPFSNTEKI-----ELRGKHNQDFIKRNIELAKESRNPVVMVDREKKRL 279
+ L ++ + EK+ +L KH++ + E E + + R ++
Sbjct: 2141 RKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKR 2200
Query: 280 VELLKDLDEKDSGLSSSEGDQSGWVVPVKGYELAVTQHQQLAEIDIKLQELSAASPTISS 339
E + +K SS+ D+ V+ E + + L + +L++ + S
Sbjct: 2201 KEAKRG--DKPKEKFSSQVDE------VESEEHFSEEMESLLD---ELEKQESLSSEEEE 2249
Query: 340 FSPRLENRNNQKPDRDGERNMEVTPGE-----------KILRNTKEQRDLHNRLREIDEK 388
E R ++ + E E GE K + K++ ++ + +EK
Sbjct: 2250 EREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEK 2309
Query: 389 LKMMKENVLESTSCLSEEQLKCLLDECILKQKSIIKLSSERKKED 433
++M E ES S EE+ C L+E + ++K I+K + K ++
Sbjct: 2310 EEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQE 2354
Score = 38.1 bits (87), Expect = 0.022
Identities = 78/403 (19%), Positives = 173/403 (42%), Gaps = 44/403 (10%)
Query: 99 ISECSDEPKLKELDSQLQDAIQKMKKLDKILAKKQRREKEIKKQGLEMR------IKLWE 152
IS+ ++ ++ Q + A+QK +K+ KI + + E+++ ++ EM +K
Sbjct: 1387 ISKKEEKKTFQKSPKQGRKAVQKERKVGKIKREMTKEERDMSEEVEEMATLEEKVVKQEG 1446
Query: 153 EIKSAKYSEAWQS--------KEEMENTKKFLSLTAVSEETVGPSHEEEDTFSSVFHTQI 204
++ + + +WQ K+ T+K S A EE +EE+
Sbjct: 1447 KLVMIERTPSWQDWKKAWDEWKQVHGETRK--SWKAWKEEWEKRLLQEEEKLHQAGEKLS 1504
Query: 205 PPEEYEMQMQKLNKDFTCDVERNESLIKSGKKPFSNTEKIELRGKHNQDFIKRNIELAKE 264
P EE + +KL + V N KS ++ + + E++ L + +++ ++ ++ +E
Sbjct: 1505 PEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEE 1564
Query: 265 SRNPVVMVDREKKRLVELLKDLDEKDSGLSSSEGDQSGWVVPVKGYELAVTQHQQLAEID 324
R+ + + K + + EK + Q + + +LA + ++LA+
Sbjct: 1565 QRH---IQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLA-QEERKLAQAY 1620
Query: 325 IKL----QELSAASPTISSFSPRLENRN---NQKPDRDGERNMEVT--------PGEKIL 369
+K+ +E++ A + L R +Q+ ++ ++ ++ EK+
Sbjct: 1621 VKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLA 1680
Query: 370 RNTKEQRDLHNRLREIDEKLKMMKENV--LESTSCLSEEQLKCLLDECILKQKSII---- 423
+ + ++ N L + E+L ++N+ E E+L+ ++E K++ +
Sbjct: 1681 KKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEG 1740
Query: 424 KLSSERKK--EDIEDVTPVFPQLSRSIISKLLNESETKVQKTE 464
KL E+KK E+ E + +LS +KL E E +Q+ E
Sbjct: 1741 KLVEEKKKLAEEEEALAWQREKLSEE-ETKLAQEEELLIQEKE 1782
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 49.7 bits (117), Expect = 7e-06
Identities = 93/449 (20%), Positives = 191/449 (42%), Gaps = 63/449 (14%)
Query: 70 DDKQESCSEKIKLAEEGSDEDLDLVQHQIISECSD--EPKLKELDS------QLQDAIQK 121
D++ E I+L+EE + L + H S S P +K +S +L DA K
Sbjct: 202 DERDEHSETIIELSEER--DGLHFLPHASSSAQSPCGSPGMKRTESRQHLSVELADAKAK 259
Query: 122 MKKLDKILAKKQRREKEIKKQ--GLEMRIKLWEEIKSAKYSEAWQSKEEMENTKKFLSLT 179
+++L + L +K + + K++ +E+ +K ++ S+A ++ + L
Sbjct: 260 IRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDE------LD 313
Query: 180 AVSEETVGPSHEEEDTFSSVFHTQIPPEE-YEMQMQKLNKDFTCDVERNESLIKSGKKPF 238
A+ E+ V E + S + ++ E Y+ ++++L +D N+ L+++
Sbjct: 314 ALREKAVRVDKLESEV--SRYKERLHDIEFYKARVEELKED-------NQVLLETKTMLE 364
Query: 239 SNTEKIELRGKHNQDFIKRNIELAKESRNPVVMVDREKKRLVELLKD--LDEKDSGLSSS 296
E R + K N++L + + + D ++K++ EL+++ E S
Sbjct: 365 DQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMD 424
Query: 297 EGDQSGWVV------------PVK--GYELAVTQHQQLAEIDIKLQELSAASPTISSFSP 342
E GW + P K G+E+ +L +++++ Q L+ + +
Sbjct: 425 ESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVD 484
Query: 343 RLENRNNQKPDRDGERNMEVTPGEKILRN--TKEQRDLHN--RLREIDEKLKMMKENVLE 398
+E N K + + N ++ +IL N +E++ L N L + K K E +E
Sbjct: 485 SVEG-NASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIE 543
Query: 399 STSCLSEEQLKCL------LDECILKQKSIIKLSSERKKEDIEDVTPVFPQLSRSIISKL 452
+ SE Q+K L L++ + + ++S+E + +DIE I+ +
Sbjct: 544 TLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEK--------ENKILHES 595
Query: 453 LNESETKVQKTEVEDADMLESEECEASKG 481
+ E+ +K+ K E E + + E KG
Sbjct: 596 IKETSSKLSKIEFEKRQIKKELEHYKEKG 624
Score = 37.0 bits (84), Expect = 0.050
Identities = 103/510 (20%), Positives = 198/510 (38%), Gaps = 92/510 (18%)
Query: 1 MDIIKGNLDGISK-PASNSRIRPGSRSSNASLEVLSTEPGSFKVDTASNLNSGKEDHSES 59
+D ++GN I K N R+ + +E+L E K + N K+ E
Sbjct: 483 VDSVEGNASKILKMEKENQRL-------SKKVEILENEIVQEKQSLQNCQNLSKDLMKEK 535
Query: 60 SNTENRRTSNDDKQESCSEKIKLAEEGSDEDLDLVQH-QIISECSDEPKLKELDSQLQDA 118
+ E + + +E+ +IK+ E+ ++ V + S+ S E ++K+++ + +
Sbjct: 536 AQLEK---TIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKIL 592
Query: 119 IQKMKKLDKILAKKQRREKEIKKQGLEMRIKLWEEIKSAKYSEAWQSKEEMENTKKFLSL 178
+ +K+ L+K + +++IKK+ LE + E + + KE KK +L
Sbjct: 593 HESIKETSSKLSKIEFEKRQIKKE-LEHYKEKGERAEELENELHHLEKENELLQKKITNL 651
Query: 179 TAVSEETVGPSHEEE-------------DTFSSVF---------HTQIPPEEYEM----- 211
E+ E D+F ++ ++Q+ E E+
Sbjct: 652 KITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVE 711
Query: 212 ----------QMQKLNKDFTCDVERNESLIKSGKKPFSNTEKIELRGKHNQDFIKRNIEL 261
Q+Q NK+ + E+ + ++ K F TE++E+ D + ++
Sbjct: 712 SLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEV-SYQGLDIENQRLQK 770
Query: 262 AKESRNPVV------MVDRE------KKRLVEL---LKDLDEKDSGLSSSEGDQSGWVVP 306
E+ N + + D E +K L EL K L++ + S E + S
Sbjct: 771 TLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKD 830
Query: 307 VKGYELAVTQHQQLAEI--------DIKLQELSAASPTISS----------FSPRLENRN 348
K E + +Q AEI ++K+ L + T+S LE N
Sbjct: 831 KKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKEN 890
Query: 349 NQKPDRDG-ERNMEVTPGEKILRNTKEQRDLHNRLREID---EKLKMMKENVLESTSCLS 404
+ R + VT E ++ + + ++N L ++ EK+ + KE +L
Sbjct: 891 KELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTD 950
Query: 405 EEQLKCLLDECILKQKSIIKLSSERKKEDI 434
+ + K L K +S +K S E K+E I
Sbjct: 951 DSRYKLLES----KLESTLKKSLEIKEEKI 976
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 49.7 bits (117), Expect = 7e-06
Identities = 93/449 (20%), Positives = 191/449 (42%), Gaps = 63/449 (14%)
Query: 70 DDKQESCSEKIKLAEEGSDEDLDLVQHQIISECSD--EPKLKELDS------QLQDAIQK 121
D++ E I+L+EE + L + H S S P +K +S +L DA K
Sbjct: 202 DERDEHSETIIELSEER--DGLHFLPHASSSAQSPCGSPGMKRTESRQHLSVELADAKAK 259
Query: 122 MKKLDKILAKKQRREKEIKKQ--GLEMRIKLWEEIKSAKYSEAWQSKEEMENTKKFLSLT 179
+++L + L +K + + K++ +E+ +K ++ S+A ++ + L
Sbjct: 260 IRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDE------LD 313
Query: 180 AVSEETVGPSHEEEDTFSSVFHTQIPPEE-YEMQMQKLNKDFTCDVERNESLIKSGKKPF 238
A+ E+ V E + S + ++ E Y+ ++++L +D N+ L+++
Sbjct: 314 ALREKAVRVDKLESEV--SRYKERLHDIEFYKARVEELKED-------NQVLLETKTMLE 364
Query: 239 SNTEKIELRGKHNQDFIKRNIELAKESRNPVVMVDREKKRLVELLKD--LDEKDSGLSSS 296
E R + K N++L + + + D ++K++ EL+++ E S
Sbjct: 365 DQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMD 424
Query: 297 EGDQSGWVV------------PVK--GYELAVTQHQQLAEIDIKLQELSAASPTISSFSP 342
E GW + P K G+E+ +L +++++ Q L+ + +
Sbjct: 425 ESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVD 484
Query: 343 RLENRNNQKPDRDGERNMEVTPGEKILRN--TKEQRDLHN--RLREIDEKLKMMKENVLE 398
+E N K + + N ++ +IL N +E++ L N L + K K E +E
Sbjct: 485 SVEG-NASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIE 543
Query: 399 STSCLSEEQLKCL------LDECILKQKSIIKLSSERKKEDIEDVTPVFPQLSRSIISKL 452
+ SE Q+K L L++ + + ++S+E + +DIE I+ +
Sbjct: 544 TLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEK--------ENKILHES 595
Query: 453 LNESETKVQKTEVEDADMLESEECEASKG 481
+ E+ +K+ K E E + + E KG
Sbjct: 596 IKETSSKLSKIEFEKRQIKKELEHYKEKG 624
Score = 40.4 bits (93), Expect = 0.005
Identities = 85/448 (18%), Positives = 186/448 (41%), Gaps = 67/448 (14%)
Query: 32 EVLSTEPGSFKVDTASNLNSGKEDHSE--SSNTENRRTSNDDKQESCSEKIKLAEEGSDE 89
+ LS E G +K ++ L ++++ E T + +T +++ SEK+K + +
Sbjct: 867 KTLSKEIGIYK-ESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQ--MNN 923
Query: 90 DLDLVQHQIISECSDEPKLKELDSQLQDAIQKMKKLDKILAKKQRREKEIKKQGLEMRIK 149
DL+ + H++ ++ +L + D + ++ + KK KE K LE R++
Sbjct: 924 DLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARLE 983
Query: 150 LWEEIKSAKYSEAWQSKEEMENTKKFLSLTAVSEETVGPSHEEEDTFSSVFHTQIPPEEY 209
+S Y++ Q ++E++ KK + E + +EE S ++
Sbjct: 984 -----ESTNYNQ--QLRQELKTVKK-------NYEALKQRQDEERMVQSSPPISGEDNKW 1029
Query: 210 EMQMQKLN------KDFTCDVERNESLIKSGKKPF-SNTEKIELRGKHNQDFI------- 255
E + Q+ KD +VERN + +++ K+ + +++E + + Q I
Sbjct: 1030 ERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQT 1089
Query: 256 ---------------KRNIELAKESRNPVVMVDREKKRLVELLKDLDEKDSGLSSSEGDQ 300
K +E + + ++++ + L++ +E +S + E +
Sbjct: 1090 VSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLK 1149
Query: 301 SGWVVPVKGYELAVTQHQQLAEIDIKLQELSAASPTISSFSPRLENRNNQKPDRDGE--- 357
S + +K +E H++ A + + L + T+ S LE + DR +
Sbjct: 1150 SLYDSLIKDHEKLELLHERQAS---EYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLK 1206
Query: 358 RNMEVTPGEKILRNTKEQRDLHNRLREI-----------DEKLKMMKENVLESTSCL--S 404
+ ++ EK+L+ +E+ L N+ E +++L +L+ T L
Sbjct: 1207 QKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKETEVLQTD 1266
Query: 405 EEQLKCLLDECILKQKSIIKLSSERKKE 432
+ LK LL+ L+Q + S+ K++
Sbjct: 1267 HKNLKSLLNNSKLEQTRLEAEFSKLKEQ 1294
Score = 37.4 bits (85), Expect = 0.038
Identities = 95/521 (18%), Positives = 200/521 (38%), Gaps = 66/521 (12%)
Query: 1 MDIIKGNLDGISK-PASNSRIRPGSRSSNASLEVLSTEPGSFKVDTASNLNSGKEDHSES 59
+D ++GN I K N R+ + +E+L E K + N K+ E
Sbjct: 483 VDSVEGNASKILKMEKENQRL-------SKKVEILENEIVQEKQSLQNCQNLSKDLMKEK 535
Query: 60 SNTENRRTSNDDKQESCSEKIKLAEEGSDEDLDLVQH-QIISECSDEPKLKELDSQLQDA 118
+ E + + +E+ +IK+ E+ ++ V + S+ S E ++K+++ + +
Sbjct: 536 AQLEK---TIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKIL 592
Query: 119 IQKMKKLDKILAKKQRREKEIKKQGLEMRIKLWEEIKSAKYSEAWQSKEEMENTKKFLSL 178
+ +K+ L+K + +++IKK+ LE + E + + KE KK +L
Sbjct: 593 HESIKETSSKLSKIEFEKRQIKKE-LEHYKEKGERAEELENELHHLEKENELLQKKITNL 651
Query: 179 TAVSEETVGPSHEEE-------------DTFSSVF---------HTQIPPEEYEM----- 211
E+ E D+F ++ ++Q+ E E+
Sbjct: 652 KITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVE 711
Query: 212 ----------QMQKLNKDFTCDVERNESLIKSGKKPFSNTEKIELRGKHNQDFIKRNIEL 261
Q+Q NK+ + E+ + ++ K F TE++E+ D + ++
Sbjct: 712 SLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEV-SYQGLDIENQRLQK 770
Query: 262 AKESRNPVVM--------VDREKKRLVELLKDLDEKDSGLSSSEGDQSGWVVPVKGYELA 313
E+ N + ++ E + L + L++L L E + E
Sbjct: 771 TLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLE-- 828
Query: 314 VTQHQQLAEIDIKL-QELSAASPTISSFSPRLENRNNQKPDRDGERNMEVTPGEKILRNT 372
+QL + + +L Q+ T+ + ++ N + E + ++
Sbjct: 829 -KDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELE 887
Query: 373 KEQRDLHNRLREIDEKLKMMKENVLESTSCLSEEQLKCLLDECILKQKSIIKLSSERKKE 432
KE ++L R + L ++E+++ L +Q+ L++ + + I L+ ER
Sbjct: 888 KENKELVKRATIDIKTLVTLREDLVSEK--LKTQQMNNDLEK-LTHELEKIGLNKERLLH 944
Query: 433 DIEDVTPVFPQLSRSIISKLLNESETKVQKTEVEDADMLES 473
D + + L + S L E K +K +A + ES
Sbjct: 945 DEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEES 985
>gi|30794488 kinesin family member 27 [Homo sapiens]
Length = 1401
Score = 49.7 bits (117), Expect = 7e-06
Identities = 95/445 (21%), Positives = 182/445 (40%), Gaps = 48/445 (10%)
Query: 51 SGKEDHSESSNTENRRTSND---DKQESCSEKIKLAEEGSDEDLDLVQHQIISECSDEPK 107
S +D ++ S+ EN D + QE +K+K +E E ++ I+ E
Sbjct: 680 SDTQDETQKSDLENEDLKIDCLQESQELNLQKLKNSERILTEAKQKMRELTINIKMKEDL 739
Query: 108 LKELDSQLQDAIQKMK----------------KLDKILAKKQRREKEIKK-QGLEMRIKL 150
+KEL DA K K++ I +KQ +E E K + M++KL
Sbjct: 740 IKELIKTGNDAKSVSKQYSLKVTKLEHDAEQAKVELIETQKQLQELENKDLSDVAMKVKL 799
Query: 151 WEEIK---SAKYSEAWQSKEEMENTKKFLSLTAVSEETVGPSHEEEDTFSSVFHTQIPPE 207
+E + A +++ +++KK SL+ +E+ ++E E + + + +I +
Sbjct: 800 QKEFRKKMDAAKLRVQVLQKKQQDSKKLASLSIQNEKR---ANELEQSVDHMKYQKIQLQ 856
Query: 208 EYEMQMQKLNKDFTCDVERNESLIKSGKKPFSNTEKIELRGKHNQDFIKRNIELAKESRN 267
+ + K ++R++ IK + E ++ + +D N++ K S
Sbjct: 857 RKLREENEKRKQLDAVIKRDQQKIKEIQLKTGQEEGLKPKA---EDLDACNLKRRKGSFG 913
Query: 268 PV---VMVDREKKRLVELLKDLDEKDSGLSSSEGDQSGWVVPVKGYELAVTQHQQLAEID 324
+ +D +KK L E ++ + + L E D V E + + L
Sbjct: 914 SIDHLQKLDEQKKWLDEEVEKVLNQRQELEELEADLKKREAIVSKKEALLQEKSHLENKK 973
Query: 325 IK-LQELSAASPTISS----FSPRLENRNNQKPDRDGERNMEVTPGEKILRNTKEQRDLH 379
++ Q L+ S IS+ L +N Q E +++ ++L+ K+Q L
Sbjct: 974 LRSSQALNTDSLKISTRLNLLEQELSEKNVQLQTSTAEEKTKISEQVEVLQKEKDQ--LQ 1031
Query: 380 NRLREIDEKLKMMKENVLESTSCLSEEQLKCLLDECILKQKSIIKLSSERKKEDIEDVTP 439
R +DEKLK VL EE + L+E I ++ I+ +E + + +
Sbjct: 1032 KRRHNVDEKLK--NGRVLSP----EEEHVLFQLEEGIEALEAAIEYRNESIQNRQKSLRA 1085
Query: 440 VFPQLSR---SIISKLLNESETKVQ 461
F LSR +++ KL S +++
Sbjct: 1086 SFHNLSRGEANVLEKLACLSPVEIR 1110
Score = 38.5 bits (88), Expect = 0.017
Identities = 94/424 (22%), Positives = 161/424 (37%), Gaps = 68/424 (16%)
Query: 110 ELDSQLQDAIQKMKKLDKILAKKQRREKEIK-KQGLEMRIKLWEEIKSAKYSEAWQSKEE 168
+L +L++ +K K+LD ++ + Q++ KEI+ K G E +K A+ +A K
Sbjct: 854 QLQRKLREENEKRKQLDAVIKRDQQKIKEIQLKTGQEEGLK-----PKAEDLDACNLKRR 908
Query: 169 MENTKKFLSLTAVSEETVGPSHEEEDTFSSVFHTQIPPEEYEMQMQKLNKDFTCDVERNE 228
+ L + E+ E E + Q Q+L ++ D+++ E
Sbjct: 909 KGSFGSIDHLQKLDEQKKWLDEEVEKVLN--------------QRQEL-EELEADLKKRE 953
Query: 229 SLIKSGKKPFSNTEKIELRGKHNQDFIKRNIELAKESRNPVVMVDREKKRLVELLKDLDE 288
+++ KK EK L K + N + K S RL L ++L E
Sbjct: 954 AIV--SKKEALLQEKSHLENKKLRSSQALNTDSLKIS-----------TRLNLLEQELSE 1000
Query: 289 KDSGLSSSEGDQSGWVVPVKGYELAVTQHQQLAE----IDIKLQELSAASPTISSFSPRL 344
K+ L +S ++ + + E+ + QL + +D KL+ SP +L
Sbjct: 1001 KNVQLQTSTAEEKTKI--SEQVEVLQKEKDQLQKRRHNVDEKLKNGRVLSPEEEHVLFQL 1058
Query: 345 ENRNNQKPDRDGERNMEVTPGEKILRNTKEQRDLHNRLREIDEKLKMMKENVLESTSCLS 404
E RN + +K LR HN L + NVLE +CLS
Sbjct: 1059 EEGIEALEAAIEYRNESIQNRQKSLR-----ASFHN--------LSRGEANVLEKLACLS 1105
Query: 405 EEQLKCLLDECILKQKSIIKLSSERKKEDIEDVTPVFPQLSRSIISKLLNESETKVQKTE 464
+++ +L K ++ L +K+ + + L R + + L ES K +
Sbjct: 1106 PVEIRTILFRYFNK---VVNLREAERKQQLYNEEMKMKVLERDNMVREL-ESALDHLKLQ 1161
Query: 465 VEDADMLESEECEASKGYYL--TKALTGHNMSEALVTEAENMKCLQFSKDVIISDTKDYF 522
+ L+ +E E L K G + E T + K Q KD+ YF
Sbjct: 1162 CDRRLTLQQKEHEQKMQLLLHHFKEQDGEGIMETFKTYED--KIQQLEKDL-------YF 1212
Query: 523 MSKT 526
KT
Sbjct: 1213 YKKT 1216
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 49.3 bits (116), Expect = 1e-05
Identities = 99/493 (20%), Positives = 199/493 (40%), Gaps = 76/493 (15%)
Query: 53 KEDHSESSNTENRRTSNDDKQESCSE------KIKLAEEGSDEDLDLVQHQIISECSDEP 106
KE H+ + +N E+ ++ ++ A + + +DL + ++ S +
Sbjct: 967 KEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKS 1026
Query: 107 KLKELDSQLQDAIQKMKKLDKILAKKQRR-------------EKEIKKQGLEMRIKLWEE 153
KL++ L+ ++++ KKL L + +R+ + E KQ L+ R+K
Sbjct: 1027 KLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKK--- 1083
Query: 154 IKSAKYSEAWQSKEEMENT------KKFLSLTAVSEETVGPSHEEEDTFSSVFHTQIPPE 207
K +Y + QSK E E T KK L A EE E T + T+
Sbjct: 1084 -KDFEYCQL-QSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAK---TEKQRS 1138
Query: 208 EYEMQMQKLNKDFTCDVERNESLIKSGKKPFSNTEKIELRGKHNQDFIKRNIELAKESRN 267
+Y ++++L+ E L ++G + +IEL K +F+K +L + +
Sbjct: 1139 DYARELEELS----------ERLEEAGGV---TSTQIELNKKREAEFLKLRRDLEEATLQ 1185
Query: 268 PVVMVDREKKRLVELLKDLDEKDSGLSSSEGDQSGWVVPVKGYELAVTQHQQLAEIDIKL 327
MV +K+ + + +L E+ L + ++ +E +++
Sbjct: 1186 HEAMVAALRKKHADSVAELGEQIDNLQ----------------RVKQKLEKEKSEFKLEI 1229
Query: 328 QELSAASPTISSFSPRLENRNNQKPDRDGE---RNMEV--TPGEKILRNTKEQRDLHNRL 382
+LS++ ++S LE D+ E +N E+ + E + ++ Q +
Sbjct: 1230 DDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELS 1289
Query: 383 REIDEKLKMMKE--NVLESTSCLSEEQLKCLLDECILKQKSIIKLSSERKKEDIEDVTPV 440
R+++EK ++ + ++ + +EE + L +E K L S R D+
Sbjct: 1290 RQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYE 1349
Query: 441 FPQLSRSIISKLLNESETKVQ--KTEVEDADMLESEECEASKGYYLTKALTGHNMSEALV 498
Q ++ + + L+++ ++V +T+ E + +EE E +K K L
Sbjct: 1350 EEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAK-----KKLAQRLQDSEEQ 1404
Query: 499 TEAENMKCLQFSK 511
EA N KC K
Sbjct: 1405 VEAVNAKCASLEK 1417
Score = 36.6 bits (83), Expect = 0.065
Identities = 64/321 (19%), Positives = 132/321 (41%), Gaps = 43/321 (13%)
Query: 103 SDEPKLKELDSQLQDAIQKMKKLDKILAKKQRREKEIKKQGLEMRIKLWEEIKSAKYSEA 162
S + +LK+ L DA++ + L + LA +RR ++ + E+R L + ++ K +E
Sbjct: 1646 SVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAE- 1704
Query: 163 WQSKEEMENTKKFLSLTAVSEETVGPSHEEEDTFSSVFHTQIPPEEYEMQMQKLNKDFTC 222
+E ++ S E V H + +S+ HT+ E MQ+Q +D +
Sbjct: 1705 ---QELLD-----------SNERVQLLHTQN---TSLIHTKKKLETDLMQLQSEVEDASR 1747
Query: 223 DVERNESLIKSGKKPFSNTEKIELRGKHNQDF------IKRNIE-LAKESRNPV-----V 270
D E + KK ++ + K QD +K+N+E K+ ++ + +
Sbjct: 1748 DARNAE---EKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQL 1804
Query: 271 MVDREKKRLVELLKDLDEKDSGLSSSEGDQSGWVVPVKGYELAVTQHQQLAEID----IK 326
+ KK++ +L + E + L + + V ++ YE V + +E D ++
Sbjct: 1805 ALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLR 1864
Query: 327 LQELSAASPTISSFSPRLENRNNQKPDRDGERNMEVTPGEKILRNTKEQRDLHNRLREID 386
LQ+L + ++++ Q + D + N +T K +E + +
Sbjct: 1865 LQDL------VDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQV 1918
Query: 387 EKLKMMKENVLESTSCLSEEQ 407
KL+ + S + E +
Sbjct: 1919 NKLRAKTRDFTSSRMVVHESE 1939
>gi|7705415 hook homolog 1 [Homo sapiens]
Length = 728
Score = 49.3 bits (116), Expect = 1e-05
Identities = 91/436 (20%), Positives = 183/436 (41%), Gaps = 66/436 (15%)
Query: 63 ENRRTSNDDKQESCSEKIKLAEEGSDEDLDLVQHQIISECSDEPKLKELDSQLQDAIQKM 122
++ + S + E +EK+ + D+ +V + +L+E + +L+ A
Sbjct: 212 QDEKNSLVSENEMMNEKLDQLDGSFDDPNTVVAKKYFHAQLQLEQLQEENFRLEAAKDDY 271
Query: 123 K----KLDKILAKKQRREKEIKKQGLEMRIKLWEEIKSAK---------------YSEAW 163
+ +L+K L + Q R E+ E R L +EI + Y +
Sbjct: 272 RVHCEELEKQLIEFQHRNDELTSLAEETRA-LKDEIDVLRATSDKANKLESTVEIYRQKL 330
Query: 164 QSKEEMENTKKFLSLTAVSEETVGPSHEEEDTFSSVFHTQIPPEEYEMQMQKLNKDFTCD 223
Q ++ K L T + S EEE ++ TQ+ E Y+ Q+Q L+ + +
Sbjct: 331 QDLNDLRKQVKTLQETNMMYMHNTVSLEEELKKANAARTQL--ETYKRQVQDLHVKLSSE 388
Query: 224 VERNESLIKSGKKPFSNTEKIELRGKHNQDFIKRNIELAKESRNPVVMVDREKKRLVELL 283
+R ++L K+ EK E K + I++ L + + E+ R ++
Sbjct: 389 SKRADTLAFEMKRL---EEKHEALLKEKERLIEQRDTLKETN---------EELRCSQVQ 436
Query: 284 KD-LDEKDSGLSSSEGDQSGWVVPVKGYELAVT-QHQQLAEIDIKLQELSAASPTISSFS 341
+D L++ D+ + S + + ++PV+ E+ + QH+ ++LQ+ + + I
Sbjct: 437 QDHLNQTDASATKSYENLAAEIMPVEYREVFIRLQHENKM---LRLQQEGSENERIEELQ 493
Query: 342 PRLENRNNQKPDRDGERNMEVTPGEKILRNTKEQRDLHNRLREIDEKLKMMKENVLESTS 401
+LE ++ + + + EQR R+RE+ ++++ +++++ E S
Sbjct: 494 EQLEQKHRKMNELE-----------------TEQRLSKERIRELQQQIEDLQKSLQEQGS 536
Query: 402 CLSEEQLKCLLDECILKQKSIIKLSSE--RKKEDIEDVTPVFPQLSRSIISKLLNESETK 459
E L + + + ++ E +K+E IED+ P Q + I NE E
Sbjct: 537 KSEGESSSKLKQKLEAHMEKLTEVHEELQKKQELIEDLQPDINQNVQKI-----NELEAA 591
Query: 460 VQKTEVEDADMLESEE 475
+QK +D DM EE
Sbjct: 592 LQK---KDEDMKAMEE 604
Score = 38.9 bits (89), Expect = 0.013
Identities = 42/187 (22%), Positives = 80/187 (42%), Gaps = 9/187 (4%)
Query: 101 ECSDEPKLKELDSQLQDAIQKMKKLDKILAKKQRREKEIKKQGLEMRIKLWEEIKSAKYS 160
E S+ +++EL QL+ +KM +L+ + R +E+++Q +++ L E+ ++
Sbjct: 482 EGSENERIEELQEQLEQKHRKMNELETEQRLSKERIRELQQQIEDLQKSLQEQGSKSEGE 541
Query: 161 EAWQSKEEMENTKKFLSLTAVSEETVGPSHEEEDTFSSVFHTQIPPEEYEMQMQKLNKDF 220
+ + K+++E + LT V EE ED + E E +QK ++D
Sbjct: 542 SSSKLKQKLEAHME--KLTEVHEELQKKQELIEDLQPDINQNVQKINELEAALQKKDEDM 599
Query: 221 TCDVERNESLIKSGKK------PFSNTEKIELRGKHNQDFIK-RNIELAKESRNPVVMVD 273
ER + ++ + P N E+ Q K R IE+ + D
Sbjct: 600 KAMEERYKMYLEKARNVIKTLDPKLNPASAEIMLLRKQLAEKERRIEILESECKVAKFRD 659
Query: 274 REKKRLV 280
E+K +V
Sbjct: 660 YEEKLIV 666
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 49.3 bits (116), Expect = 1e-05
Identities = 96/488 (19%), Positives = 190/488 (38%), Gaps = 57/488 (11%)
Query: 15 ASNSRIRPGSRS-SNASLEVLSTEPGSFK--VDTASNLNSGKEDHSESSNT--ENRRTSN 69
AS +R SRS S S + L E G F+ + A+ L + E+ E+
Sbjct: 1769 ASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQR 1828
Query: 70 DDKQESCSEKI-------------KLAEEGSDEDLDLVQHQIISECSDEPKLKELDSQLQ 116
+ + +EK+ ++A + + + + ++ E +L+E +Q +
Sbjct: 1829 AEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK 1888
Query: 117 -DAIQKMKKLDKILAKKQRREKEIKKQGLEMRIKLWEEIKS--AKYSEAWQSKEEMENTK 173
D +++ +L K + R+K + + L R ++ EEI + A + +A K E+E
Sbjct: 1889 ADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELE--- 1945
Query: 174 KFLSLTAVSEETVGPSHEEEDTFSSVFHTQIPPEEYEMQMQKLNKDFTCDVERNESLIKS 233
L L + EDT S E+ E++ + + + R +
Sbjct: 1946 --LELGRIRSNA-------EDTLRS-------KEQAELEAARQRQLAAEEERRRREAEER 1989
Query: 234 GKKPFSNTEKIELRGKHNQDFIKRNIELAKESRNPVVMVDREKKRLVELLKDLDEKDSGL 293
+K + E+ + K + ++R +E+R ++E R ++L ++ +K
Sbjct: 1990 VQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQK---R 2046
Query: 294 SSSEGDQSGWVVPVKGYELAVTQHQQLAEIDIKLQELSAASPTISSFSPRLENRNNQKPD 353
+E + V K EL T Q+ + +D E AA + E Q
Sbjct: 2047 LQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRA----AEEAEEARVQAER 2102
Query: 354 RDGERNMEVTPGEKILRNTKEQRDLHNRLREIDEKLKMMKENVLESTSCLSEEQLKCLLD 413
+ +V E++ ++ +EQ + + EKL+ E E + +
Sbjct: 2103 EAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAE---------QEAARRAQAE 2153
Query: 414 ECILKQKSIIKLSSERKKEDIEDVTPVFPQLSRSIISKLLNESETKVQKTEV-EDADMLE 472
+ L+QK E+ K+ E Q+ + + + L ET QK + E+ L+
Sbjct: 2154 QAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLK 2213
Query: 473 SEECEASK 480
+E EA++
Sbjct: 2214 AEATEAAR 2221
Score = 43.9 bits (102), Expect = 4e-04
Identities = 76/434 (17%), Positives = 172/434 (39%), Gaps = 56/434 (12%)
Query: 5 KGNLDGISKPASNSRIRPGSRSSNASLEVLSTEPGSFKVDTASNLNSGKEDHSESSNTEN 64
K L+ ++ PA +++ GS S L T T+ + E E
Sbjct: 1290 KAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRME--EE 1347
Query: 65 RRTSNDDKQESCSEKIKLAEEGSDEDLDLVQHQIISECSDEPKLKELDSQLQDAIQKMKK 124
R + + E E++ E ++ L + ++ E + KEL ++Q+ + + ++
Sbjct: 1348 ERLAEQQRAEE-RERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREE 1406
Query: 125 LDKILAKKQRR--EKEIKKQGLEMRIKLWEEIKSAKYSEAWQSKEEMENTKKFLSLTAVS 182
+ A++Q+R ++E+++ ++ + + A+ +E + + E E L L A
Sbjct: 1407 A-AVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATE 1465
Query: 183 EETVGPSHEEEDTFSSVFHTQIPPEEYEMQMQKLNKDFTCDVERNESLIKSGKKPFSNTE 242
+ G E + + + + + + ++L + + +R
Sbjct: 1466 RQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQA------------ 1513
Query: 243 KIELRGKHNQDFIKRNIELAKESRNPVVMVDREKKRLVELLKDLDEKDSGLSSSEGDQSG 302
++EL + +K E A+E + R + L EL +E + L +E +++
Sbjct: 1514 EVELASR-----VKAEAEAAREKQ-------RALQALEELRLQAEEAERRLRQAEVERAR 1561
Query: 303 WVVPVKGYELAVTQHQQLAEIDIKLQELSAASPTISSFSPRLENRNNQKPDRDGERNMEV 362
V ++A+ Q+ AE +++ + S A T ER+++
Sbjct: 1562 QV------QVALETAQRSAEAELQSKRASFAEKTAQL-----------------ERSLQE 1598
Query: 363 TPGEKILRNTKEQRDLHNRLREIDEKLKMMKENVLESTSCLSEEQLKCLLD-ECILKQKS 421
+ +E+ + + + E+ + E LE + E L+ L E + +QKS
Sbjct: 1599 E--HVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKS 1656
Query: 422 IIKLSSERKKEDIE 435
+ + +E++KE+ E
Sbjct: 1657 LAQAEAEKQKEEAE 1670
Score = 32.7 bits (73), Expect = 0.94
Identities = 45/241 (18%), Positives = 107/241 (44%), Gaps = 33/241 (13%)
Query: 74 ESCSEKIKLAEEGSDEDLDLVQHQIISECSDEPKLKELDSQLQDAIQKMKKLDKILAKKQ 133
E EK+ E + E + LVQ L+ Q Q + ++L + +A+ +
Sbjct: 2411 EEIGEKLHRTELATQEKVTLVQ--------------TLEIQRQQSDHDAERLREAIAELE 2456
Query: 134 RREKEIKKQGLEMRIKLWEEIKSAKYSEAWQSKEEMENTKKFLSLTAVSEETVGPSHEEE 193
R +++++++ +++K EE+++ + + Q + ++ + FLS + +E+
Sbjct: 2457 REKEKLQQEAKLLQLKS-EEMQTVQQEQLLQETQALQ--QSFLSEKDSLLQRERFIEQEK 2513
Query: 194 DTFSSVFHTQIPP-----EEYEMQMQKLNKDFTCDVERNESLIKSGKKPFSNTEKIELRG 248
+F ++ EE + Q Q++ ++ + L+ S ++ + E
Sbjct: 2514 AKLEQLFQDEVAKAQQLREEQQRQQQQMEQE-------RQRLVASMEEARRRQHEAEEGV 2566
Query: 249 KHNQDFIKRNIELAKESRNPVVMVDREKKRLVELLKDLDEKD-SGLSSSEGDQSGWVVPV 307
+ Q+ ++ +L ++ R ++ E +RL E L+ L+E+ + L+ SE + V
Sbjct: 2567 RRKQEELQ---QLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAAT 2623
Query: 308 K 308
K
Sbjct: 2624 K 2624
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 49.3 bits (116), Expect = 1e-05
Identities = 96/488 (19%), Positives = 190/488 (38%), Gaps = 57/488 (11%)
Query: 15 ASNSRIRPGSRS-SNASLEVLSTEPGSFK--VDTASNLNSGKEDHSESSNT--ENRRTSN 69
AS +R SRS S S + L E G F+ + A+ L + E+ E+
Sbjct: 1773 ASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQR 1832
Query: 70 DDKQESCSEKI-------------KLAEEGSDEDLDLVQHQIISECSDEPKLKELDSQLQ 116
+ + +EK+ ++A + + + + ++ E +L+E +Q +
Sbjct: 1833 AEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHK 1892
Query: 117 -DAIQKMKKLDKILAKKQRREKEIKKQGLEMRIKLWEEIKS--AKYSEAWQSKEEMENTK 173
D +++ +L K + R+K + + L R ++ EEI + A + +A K E+E
Sbjct: 1893 ADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELE--- 1949
Query: 174 KFLSLTAVSEETVGPSHEEEDTFSSVFHTQIPPEEYEMQMQKLNKDFTCDVERNESLIKS 233
L L + EDT S E+ E++ + + + R +
Sbjct: 1950 --LELGRIRSNA-------EDTLRS-------KEQAELEAARQRQLAAEEERRRREAEER 1993
Query: 234 GKKPFSNTEKIELRGKHNQDFIKRNIELAKESRNPVVMVDREKKRLVELLKDLDEKDSGL 293
+K + E+ + K + ++R +E+R ++E R ++L ++ +K
Sbjct: 1994 VQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQK---R 2050
Query: 294 SSSEGDQSGWVVPVKGYELAVTQHQQLAEIDIKLQELSAASPTISSFSPRLENRNNQKPD 353
+E + V K EL T Q+ + +D E AA + E Q
Sbjct: 2051 LQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRA----AEEAEEARVQAER 2106
Query: 354 RDGERNMEVTPGEKILRNTKEQRDLHNRLREIDEKLKMMKENVLESTSCLSEEQLKCLLD 413
+ +V E++ ++ +EQ + + EKL+ E E + +
Sbjct: 2107 EAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAE---------QEAARRAQAE 2157
Query: 414 ECILKQKSIIKLSSERKKEDIEDVTPVFPQLSRSIISKLLNESETKVQKTEV-EDADMLE 472
+ L+QK E+ K+ E Q+ + + + L ET QK + E+ L+
Sbjct: 2158 QAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLK 2217
Query: 473 SEECEASK 480
+E EA++
Sbjct: 2218 AEATEAAR 2225
Score = 43.9 bits (102), Expect = 4e-04
Identities = 76/434 (17%), Positives = 172/434 (39%), Gaps = 56/434 (12%)
Query: 5 KGNLDGISKPASNSRIRPGSRSSNASLEVLSTEPGSFKVDTASNLNSGKEDHSESSNTEN 64
K L+ ++ PA +++ GS S L T T+ + E E
Sbjct: 1294 KAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRME--EE 1351
Query: 65 RRTSNDDKQESCSEKIKLAEEGSDEDLDLVQHQIISECSDEPKLKELDSQLQDAIQKMKK 124
R + + E E++ E ++ L + ++ E + KEL ++Q+ + + ++
Sbjct: 1352 ERLAEQQRAEE-RERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREE 1410
Query: 125 LDKILAKKQRR--EKEIKKQGLEMRIKLWEEIKSAKYSEAWQSKEEMENTKKFLSLTAVS 182
+ A++Q+R ++E+++ ++ + + A+ +E + + E E L L A
Sbjct: 1411 A-AVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATE 1469
Query: 183 EETVGPSHEEEDTFSSVFHTQIPPEEYEMQMQKLNKDFTCDVERNESLIKSGKKPFSNTE 242
+ G E + + + + + + ++L + + +R
Sbjct: 1470 RQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQA------------ 1517
Query: 243 KIELRGKHNQDFIKRNIELAKESRNPVVMVDREKKRLVELLKDLDEKDSGLSSSEGDQSG 302
++EL + +K E A+E + R + L EL +E + L +E +++
Sbjct: 1518 EVELASR-----VKAEAEAAREKQ-------RALQALEELRLQAEEAERRLRQAEVERAR 1565
Query: 303 WVVPVKGYELAVTQHQQLAEIDIKLQELSAASPTISSFSPRLENRNNQKPDRDGERNMEV 362
V ++A+ Q+ AE +++ + S A T ER+++
Sbjct: 1566 QV------QVALETAQRSAEAELQSKRASFAEKTAQL-----------------ERSLQE 1602
Query: 363 TPGEKILRNTKEQRDLHNRLREIDEKLKMMKENVLESTSCLSEEQLKCLLD-ECILKQKS 421
+ +E+ + + + E+ + E LE + E L+ L E + +QKS
Sbjct: 1603 E--HVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKS 1660
Query: 422 IIKLSSERKKEDIE 435
+ + +E++KE+ E
Sbjct: 1661 LAQAEAEKQKEEAE 1674
Score = 32.7 bits (73), Expect = 0.94
Identities = 45/241 (18%), Positives = 107/241 (44%), Gaps = 33/241 (13%)
Query: 74 ESCSEKIKLAEEGSDEDLDLVQHQIISECSDEPKLKELDSQLQDAIQKMKKLDKILAKKQ 133
E EK+ E + E + LVQ L+ Q Q + ++L + +A+ +
Sbjct: 2415 EEIGEKLHRTELATQEKVTLVQ--------------TLEIQRQQSDHDAERLREAIAELE 2460
Query: 134 RREKEIKKQGLEMRIKLWEEIKSAKYSEAWQSKEEMENTKKFLSLTAVSEETVGPSHEEE 193
R +++++++ +++K EE+++ + + Q + ++ + FLS + +E+
Sbjct: 2461 REKEKLQQEAKLLQLKS-EEMQTVQQEQLLQETQALQ--QSFLSEKDSLLQRERFIEQEK 2517
Query: 194 DTFSSVFHTQIPP-----EEYEMQMQKLNKDFTCDVERNESLIKSGKKPFSNTEKIELRG 248
+F ++ EE + Q Q++ ++ + L+ S ++ + E
Sbjct: 2518 AKLEQLFQDEVAKAQQLREEQQRQQQQMEQE-------RQRLVASMEEARRRQHEAEEGV 2570
Query: 249 KHNQDFIKRNIELAKESRNPVVMVDREKKRLVELLKDLDEKD-SGLSSSEGDQSGWVVPV 307
+ Q+ ++ +L ++ R ++ E +RL E L+ L+E+ + L+ SE + V
Sbjct: 2571 RRKQEELQ---QLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAAT 2627
Query: 308 K 308
K
Sbjct: 2628 K 2628
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.125 0.335
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,291,144
Number of Sequences: 37866
Number of extensions: 946283
Number of successful extensions: 6710
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 69
Number of HSP's successfully gapped in prelim test: 678
Number of HSP's that attempted gapping in prelim test: 5031
Number of HSP's gapped (non-prelim): 1847
length of query: 581
length of database: 18,247,518
effective HSP length: 108
effective length of query: 473
effective length of database: 14,157,990
effective search space: 6696729270
effective search space used: 6696729270
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.